10033 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 10033 R-BTA-9026967 https://reactome.org/PathwayBrowser/#/R-BTA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Bos taurus 10033 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 10033 R-CFA-9026967 https://reactome.org/PathwayBrowser/#/R-CFA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Canis familiaris 10033 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 10033 R-DME-9026967 https://reactome.org/PathwayBrowser/#/R-DME-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Drosophila melanogaster 10033 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 10033 R-HSA-9026967 https://reactome.org/PathwayBrowser/#/R-HSA-9026967 VKORC1 inhibitors binds VKORC1 dimer TAS Homo sapiens 10033 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 10033 R-MMU-9026967 https://reactome.org/PathwayBrowser/#/R-MMU-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Mus musculus 10033 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 10033 R-RNO-9026967 https://reactome.org/PathwayBrowser/#/R-RNO-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Rattus norvegicus 10033 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 10033 R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa 10033 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 10033 R-XTR-9026967 https://reactome.org/PathwayBrowser/#/R-XTR-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Xenopus tropicalis 10036 R-BTA-5696424 https://reactome.org/PathwayBrowser/#/R-BTA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Bos taurus 10036 R-CEL-5696424 https://reactome.org/PathwayBrowser/#/R-CEL-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Caenorhabditis elegans 10036 R-CFA-5696424 https://reactome.org/PathwayBrowser/#/R-CFA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Canis familiaris 10036 R-DDI-5696424 https://reactome.org/PathwayBrowser/#/R-DDI-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Dictyostelium discoideum 10036 R-DME-5696424 https://reactome.org/PathwayBrowser/#/R-DME-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Drosophila melanogaster 10036 R-DRE-5696424 https://reactome.org/PathwayBrowser/#/R-DRE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Danio rerio 10036 R-GGA-5696424 https://reactome.org/PathwayBrowser/#/R-GGA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Gallus gallus 10036 R-HSA-5696424 https://reactome.org/PathwayBrowser/#/R-HSA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters TAS Homo sapiens 10036 R-MMU-5696424 https://reactome.org/PathwayBrowser/#/R-MMU-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Mus musculus 10036 R-RNO-5696424 https://reactome.org/PathwayBrowser/#/R-RNO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Rattus norvegicus 10036 R-SCE-5696424 https://reactome.org/PathwayBrowser/#/R-SCE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Saccharomyces cerevisiae 10036 R-SPO-5696424 https://reactome.org/PathwayBrowser/#/R-SPO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Schizosaccharomyces pombe 10036 R-XTR-5696424 https://reactome.org/PathwayBrowser/#/R-XTR-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Xenopus tropicalis 10055 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 10055 R-BTA-9611721 https://reactome.org/PathwayBrowser/#/R-BTA-9611721 β1-agonists bind ADRB1 IEA Bos taurus 10055 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 10055 R-DME-9611721 https://reactome.org/PathwayBrowser/#/R-DME-9611721 β1-agonists bind ADRB1 IEA Drosophila melanogaster 10055 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 10055 R-DRE-9611721 https://reactome.org/PathwayBrowser/#/R-DRE-9611721 β1-agonists bind ADRB1 IEA Danio rerio 10055 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 10055 R-GGA-9611721 https://reactome.org/PathwayBrowser/#/R-GGA-9611721 β1-agonists bind ADRB1 IEA Gallus gallus 10055 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 10055 R-HSA-9611721 https://reactome.org/PathwayBrowser/#/R-HSA-9611721 β1-agonists bind ADRB1 TAS Homo sapiens 10055 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 10055 R-MMU-9611721 https://reactome.org/PathwayBrowser/#/R-MMU-9611721 β1-agonists bind ADRB1 IEA Mus musculus 10055 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 10055 R-RNO-9611721 https://reactome.org/PathwayBrowser/#/R-RNO-9611721 β1-agonists bind ADRB1 IEA Rattus norvegicus 10055 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 10055 R-SSC-9611721 https://reactome.org/PathwayBrowser/#/R-SSC-9611721 β1-agonists bind ADRB1 IEA Sus scrofa 10055 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 10055 R-XTR-9611721 https://reactome.org/PathwayBrowser/#/R-XTR-9611721 β1-agonists bind ADRB1 IEA Xenopus tropicalis 10093 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 10093 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 10093 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 10093 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 10093 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 10093 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 10093 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 10093 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 10093 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 10093 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 10093 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 10093 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 10093 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 10093 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 10093 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 10093 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 10093 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 10093 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 10093 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 10093 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 10093 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 10093 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 10093 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 10093 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 10093 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 10093 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 10093 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 10093 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 10093 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 10093 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 10093 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 10093 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 10093 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 10093 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 10093 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 10093 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 10093 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 10093 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 10093 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 10093 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 10093 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 10093 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 10119 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 10119 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 10119 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 10119 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 10119 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 10119 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 10119 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 10119 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 10119 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 10119 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 10119 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 10119 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 10119 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 10119 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 10119 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 10119 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 10119 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 10119 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 10119 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 10119 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 10119 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 10119 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 10119 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 10119 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 10119 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 10119 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 10119 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 10119 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 101278 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 101278 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 101278 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 101278 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 101278 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 101278 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 101278 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 101278 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 101278 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 101278 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 103854 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 103854 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 103854 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 103854 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 103854 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 103854 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 103854 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 103854 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 103854 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 103854 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 103854 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 103854 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 103854 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 103854 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 103854 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 103854 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 103854 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 103854 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 103854 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 103854 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 103854 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 103854 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 104011 R-BTA-561041 https://reactome.org/PathwayBrowser/#/R-BTA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Bos taurus 104011 R-CEL-561041 https://reactome.org/PathwayBrowser/#/R-CEL-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Caenorhabditis elegans 104011 R-CFA-561041 https://reactome.org/PathwayBrowser/#/R-CFA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Canis familiaris 104011 R-DME-561041 https://reactome.org/PathwayBrowser/#/R-DME-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Drosophila melanogaster 104011 R-DRE-561041 https://reactome.org/PathwayBrowser/#/R-DRE-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Danio rerio 104011 R-GGA-561041 https://reactome.org/PathwayBrowser/#/R-GGA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Gallus gallus 104011 R-HSA-561041 https://reactome.org/PathwayBrowser/#/R-HSA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids TAS Homo sapiens 104011 R-MMU-561041 https://reactome.org/PathwayBrowser/#/R-MMU-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Mus musculus 104011 R-RNO-561041 https://reactome.org/PathwayBrowser/#/R-RNO-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Rattus norvegicus 104011 R-SSC-561041 https://reactome.org/PathwayBrowser/#/R-SSC-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Sus scrofa 104011 R-XTR-561041 https://reactome.org/PathwayBrowser/#/R-XTR-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Xenopus tropicalis 104023 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 104023 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 104023 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 104023 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 104023 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 104023 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 104023 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 104023 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 104023 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 104023 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 104023 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 104023 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 104023 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 104023 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 104023 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 104023 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 104023 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 104023 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 104023 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 104023 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 10545 R-BTA-140359 https://reactome.org/PathwayBrowser/#/R-BTA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Bos taurus 10545 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 10545 R-BTA-917805 https://reactome.org/PathwayBrowser/#/R-BTA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Bos taurus 10545 R-CEL-917805 https://reactome.org/PathwayBrowser/#/R-CEL-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Caenorhabditis elegans 10545 R-CFA-140359 https://reactome.org/PathwayBrowser/#/R-CFA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Canis familiaris 10545 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 10545 R-CFA-917805 https://reactome.org/PathwayBrowser/#/R-CFA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Canis familiaris 10545 R-DME-917805 https://reactome.org/PathwayBrowser/#/R-DME-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Drosophila melanogaster 10545 R-DRE-140359 https://reactome.org/PathwayBrowser/#/R-DRE-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Danio rerio 10545 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 10545 R-DRE-917805 https://reactome.org/PathwayBrowser/#/R-DRE-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Danio rerio 10545 R-GGA-140359 https://reactome.org/PathwayBrowser/#/R-GGA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Gallus gallus 10545 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 10545 R-GGA-917805 https://reactome.org/PathwayBrowser/#/R-GGA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Gallus gallus 10545 R-HSA-140359 https://reactome.org/PathwayBrowser/#/R-HSA-140359 PGG2 is reduced to PGH2 by PTGS1 TAS Homo sapiens 10545 R-HSA-1497824 https://reactome.org/PathwayBrowser/#/R-HSA-1497824 BH4 is oxidised to the BH3 radical during the eNOS catalytic cycle TAS Homo sapiens 10545 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 10545 R-HSA-3785704 https://reactome.org/PathwayBrowser/#/R-HSA-3785704 DSB inducing agents induce double strand DNA breaks TAS Homo sapiens 10545 R-HSA-917805 https://reactome.org/PathwayBrowser/#/R-HSA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ TAS Homo sapiens 10545 R-MMU-140359 https://reactome.org/PathwayBrowser/#/R-MMU-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Mus musculus 10545 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 10545 R-MMU-917805 https://reactome.org/PathwayBrowser/#/R-MMU-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Mus musculus 10545 R-MTU-879266 https://reactome.org/PathwayBrowser/#/R-MTU-879266 mycothiol is oxidized to mycothione TAS Mycobacterium tuberculosis 10545 R-RNO-140359 https://reactome.org/PathwayBrowser/#/R-RNO-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Rattus norvegicus 10545 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 10545 R-RNO-917805 https://reactome.org/PathwayBrowser/#/R-RNO-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Rattus norvegicus 10545 R-SSC-140359 https://reactome.org/PathwayBrowser/#/R-SSC-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Sus scrofa 10545 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 10545 R-SSC-917805 https://reactome.org/PathwayBrowser/#/R-SSC-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Sus scrofa 10545 R-XTR-140359 https://reactome.org/PathwayBrowser/#/R-XTR-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Xenopus tropicalis 10545 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 10545 R-XTR-917805 https://reactome.org/PathwayBrowser/#/R-XTR-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Xenopus tropicalis 10668 R-HSA-5696807 https://reactome.org/PathwayBrowser/#/R-HSA-5696807 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696810 https://reactome.org/PathwayBrowser/#/R-HSA-5696810 RNase P cleaves the 5' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696813 https://reactome.org/PathwayBrowser/#/R-HSA-5696813 TSEN complex cleaves the intron from pre-tRNA TAS Homo sapiens 10668 R-HSA-5696815 https://reactome.org/PathwayBrowser/#/R-HSA-5696815 ELAC2 cleaves the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696816 https://reactome.org/PathwayBrowser/#/R-HSA-5696816 tRNA ligase complex ligates tRNA exons TAS Homo sapiens 10668 R-HSA-6782388 https://reactome.org/PathwayBrowser/#/R-HSA-6782388 NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) IEA Homo sapiens 10668 R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6786583 https://reactome.org/PathwayBrowser/#/R-HSA-6786583 PUS7 transforms uridine to pseudouridine in tRNAs IEA Homo sapiens 10668 R-HSA-6786854 https://reactome.org/PathwayBrowser/#/R-HSA-6786854 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript TAS Homo sapiens 10668 R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-9836585 https://reactome.org/PathwayBrowser/#/R-HSA-9836585 SUPV3L1:PNPT1 hydrolyzes mitochondrial RNA to yield 4-5 nucleotide oligoribonucleotides TAS Homo sapiens 10668 R-HSA-9836927 https://reactome.org/PathwayBrowser/#/R-HSA-9836927 SUPV3L1 unwinds double-stranded mitochondiral RNA TAS Homo sapiens 10668 R-SCE-6786558 https://reactome.org/PathwayBrowser/#/R-SCE-6786558 PUS7 transforms uridine to pseudouridine at nucleotide 13 of tRNA TAS Saccharomyces cerevisiae 10668 R-SCE-6790166 https://reactome.org/PathwayBrowser/#/R-SCE-6790166 PUS1 transforms uridine residues to pseudouridine in unspliced tRNA(Ile,Tyr) TAS Saccharomyces cerevisiae 10668 R-SCE-6790189 https://reactome.org/PathwayBrowser/#/R-SCE-6790189 NCL1 (TRM4) methylates cytidine-34 of unspliced tRNA(Leu) yielding 5-methylcytidine-34 TAS Saccharomyces cerevisiae 10723 R-BTA-109998 https://reactome.org/PathwayBrowser/#/R-BTA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Bos taurus 10723 R-BTA-77344 https://reactome.org/PathwayBrowser/#/R-BTA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Bos taurus 10723 R-BTA-77345 https://reactome.org/PathwayBrowser/#/R-BTA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Bos taurus 10723 R-BTA-8952873 https://reactome.org/PathwayBrowser/#/R-BTA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Bos taurus 10723 R-CEL-77344 https://reactome.org/PathwayBrowser/#/R-CEL-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Caenorhabditis elegans 10723 R-CEL-77345 https://reactome.org/PathwayBrowser/#/R-CEL-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 10723 R-CEL-8952873 https://reactome.org/PathwayBrowser/#/R-CEL-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Caenorhabditis elegans 10723 R-CFA-109998 https://reactome.org/PathwayBrowser/#/R-CFA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Canis familiaris 10723 R-CFA-77344 https://reactome.org/PathwayBrowser/#/R-CFA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Canis familiaris 10723 R-CFA-77345 https://reactome.org/PathwayBrowser/#/R-CFA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Canis familiaris 10723 R-CFA-8952873 https://reactome.org/PathwayBrowser/#/R-CFA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Canis familiaris 10723 R-DDI-77344 https://reactome.org/PathwayBrowser/#/R-DDI-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Dictyostelium discoideum 10723 R-DDI-8952873 https://reactome.org/PathwayBrowser/#/R-DDI-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Dictyostelium discoideum 10723 R-DME-109998 https://reactome.org/PathwayBrowser/#/R-DME-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Drosophila melanogaster 10723 R-DME-77344 https://reactome.org/PathwayBrowser/#/R-DME-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Drosophila melanogaster 10723 R-DME-77345 https://reactome.org/PathwayBrowser/#/R-DME-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 10723 R-DME-8952873 https://reactome.org/PathwayBrowser/#/R-DME-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Drosophila melanogaster 10723 R-DRE-8952873 https://reactome.org/PathwayBrowser/#/R-DRE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Danio rerio 10723 R-GGA-109998 https://reactome.org/PathwayBrowser/#/R-GGA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Gallus gallus 10723 R-GGA-77345 https://reactome.org/PathwayBrowser/#/R-GGA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Gallus gallus 10723 R-GGA-8952873 https://reactome.org/PathwayBrowser/#/R-GGA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Gallus gallus 10723 R-HSA-109998 https://reactome.org/PathwayBrowser/#/R-HSA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA TAS Homo sapiens 10723 R-HSA-77344 https://reactome.org/PathwayBrowser/#/R-HSA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA TAS Homo sapiens 10723 R-HSA-77345 https://reactome.org/PathwayBrowser/#/R-HSA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 TAS Homo sapiens 10723 R-HSA-8952873 https://reactome.org/PathwayBrowser/#/R-HSA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA TAS Homo sapiens 10723 R-MMU-109998 https://reactome.org/PathwayBrowser/#/R-MMU-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Mus musculus 10723 R-MMU-77344 https://reactome.org/PathwayBrowser/#/R-MMU-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Mus musculus 10723 R-MMU-77345 https://reactome.org/PathwayBrowser/#/R-MMU-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Mus musculus 10723 R-MMU-8952873 https://reactome.org/PathwayBrowser/#/R-MMU-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Mus musculus 10723 R-RNO-109998 https://reactome.org/PathwayBrowser/#/R-RNO-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Rattus norvegicus 10723 R-RNO-77344 https://reactome.org/PathwayBrowser/#/R-RNO-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Rattus norvegicus 10723 R-RNO-77345 https://reactome.org/PathwayBrowser/#/R-RNO-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 10723 R-RNO-8952873 https://reactome.org/PathwayBrowser/#/R-RNO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Rattus norvegicus 10723 R-SCE-8952873 https://reactome.org/PathwayBrowser/#/R-SCE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Saccharomyces cerevisiae 10723 R-SPO-8952873 https://reactome.org/PathwayBrowser/#/R-SPO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Schizosaccharomyces pombe 10723 R-SSC-109998 https://reactome.org/PathwayBrowser/#/R-SSC-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Sus scrofa 10723 R-SSC-77344 https://reactome.org/PathwayBrowser/#/R-SSC-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Sus scrofa 10723 R-SSC-77345 https://reactome.org/PathwayBrowser/#/R-SSC-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Sus scrofa 10723 R-SSC-8952873 https://reactome.org/PathwayBrowser/#/R-SSC-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Sus scrofa 10723 R-XTR-109998 https://reactome.org/PathwayBrowser/#/R-XTR-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Xenopus tropicalis 10723 R-XTR-77344 https://reactome.org/PathwayBrowser/#/R-XTR-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Xenopus tropicalis 10723 R-XTR-8952873 https://reactome.org/PathwayBrowser/#/R-XTR-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Xenopus tropicalis 10983 R-BTA-5696457 https://reactome.org/PathwayBrowser/#/R-BTA-5696457 BDH2 dehydrogenates 3HBA IEA Bos taurus 10983 R-CFA-5696457 https://reactome.org/PathwayBrowser/#/R-CFA-5696457 BDH2 dehydrogenates 3HBA IEA Canis familiaris 10983 R-DRE-5696457 https://reactome.org/PathwayBrowser/#/R-DRE-5696457 BDH2 dehydrogenates 3HBA IEA Danio rerio 10983 R-GGA-5696457 https://reactome.org/PathwayBrowser/#/R-GGA-5696457 BDH2 dehydrogenates 3HBA IEA Gallus gallus 10983 R-HSA-5696457 https://reactome.org/PathwayBrowser/#/R-HSA-5696457 BDH2 dehydrogenates 3HBA TAS Homo sapiens 10983 R-MMU-5696457 https://reactome.org/PathwayBrowser/#/R-MMU-5696457 BDH2 dehydrogenates 3HBA IEA Mus musculus 10983 R-RNO-5696457 https://reactome.org/PathwayBrowser/#/R-RNO-5696457 BDH2 dehydrogenates 3HBA IEA Rattus norvegicus 10983 R-SSC-5696457 https://reactome.org/PathwayBrowser/#/R-SSC-5696457 BDH2 dehydrogenates 3HBA IEA Sus scrofa 10986 R-BTA-196753 https://reactome.org/PathwayBrowser/#/R-BTA-196753 2xPPCS ligates PPanK with Cys IEA Bos taurus 10986 R-BTA-196857 https://reactome.org/PathwayBrowser/#/R-BTA-196857 PANK2 phosphorylates PanK IEA Bos taurus 10986 R-BTA-199203 https://reactome.org/PathwayBrowser/#/R-BTA-199203 PANK1/3 phosphorylate PanK IEA Bos taurus 10986 R-CEL-196753 https://reactome.org/PathwayBrowser/#/R-CEL-196753 2xPPCS ligates PPanK with Cys IEA Caenorhabditis elegans 10986 R-CFA-196753 https://reactome.org/PathwayBrowser/#/R-CFA-196753 2xPPCS ligates PPanK with Cys IEA Canis familiaris 10986 R-CFA-196857 https://reactome.org/PathwayBrowser/#/R-CFA-196857 PANK2 phosphorylates PanK IEA Canis familiaris 10986 R-CFA-199203 https://reactome.org/PathwayBrowser/#/R-CFA-199203 PANK1/3 phosphorylate PanK IEA Canis familiaris 10986 R-DDI-196753 https://reactome.org/PathwayBrowser/#/R-DDI-196753 2xPPCS ligates PPanK with Cys IEA Dictyostelium discoideum 10986 R-DME-196753 https://reactome.org/PathwayBrowser/#/R-DME-196753 2xPPCS ligates PPanK with Cys IEA Drosophila melanogaster 10986 R-DME-196857 https://reactome.org/PathwayBrowser/#/R-DME-196857 PANK2 phosphorylates PanK IEA Drosophila melanogaster 10986 R-DME-199203 https://reactome.org/PathwayBrowser/#/R-DME-199203 PANK1/3 phosphorylate PanK IEA Drosophila melanogaster 10986 R-DRE-196753 https://reactome.org/PathwayBrowser/#/R-DRE-196753 2xPPCS ligates PPanK with Cys IEA Danio rerio 10986 R-DRE-199203 https://reactome.org/PathwayBrowser/#/R-DRE-199203 PANK1/3 phosphorylate PanK IEA Danio rerio 10986 R-GGA-196753 https://reactome.org/PathwayBrowser/#/R-GGA-196753 2xPPCS ligates PPanK with Cys IEA Gallus gallus 10986 R-GGA-196857 https://reactome.org/PathwayBrowser/#/R-GGA-196857 PANK2 phosphorylates PanK IEA Gallus gallus 10986 R-GGA-199203 https://reactome.org/PathwayBrowser/#/R-GGA-199203 PANK1/3 phosphorylate PanK IEA Gallus gallus 10986 R-HSA-196753 https://reactome.org/PathwayBrowser/#/R-HSA-196753 2xPPCS ligates PPanK with Cys TAS Homo sapiens 10986 R-HSA-196857 https://reactome.org/PathwayBrowser/#/R-HSA-196857 PANK2 phosphorylates PanK TAS Homo sapiens 10986 R-HSA-199203 https://reactome.org/PathwayBrowser/#/R-HSA-199203 PANK1/3 phosphorylate PanK TAS Homo sapiens 10986 R-MMU-196753 https://reactome.org/PathwayBrowser/#/R-MMU-196753 2xPPCS ligates PPanK with Cys IEA Mus musculus 10986 R-MMU-196857 https://reactome.org/PathwayBrowser/#/R-MMU-196857 PANK2 phosphorylates PanK IEA Mus musculus 10986 R-MMU-199203 https://reactome.org/PathwayBrowser/#/R-MMU-199203 PANK1/3 phosphorylate PanK IEA Mus musculus 10986 R-PFA-196753 https://reactome.org/PathwayBrowser/#/R-PFA-196753 2xPPCS ligates PPanK with Cys IEA Plasmodium falciparum 10986 R-RNO-196753 https://reactome.org/PathwayBrowser/#/R-RNO-196753 2xPPCS ligates PPanK with Cys IEA Rattus norvegicus 10986 R-RNO-196857 https://reactome.org/PathwayBrowser/#/R-RNO-196857 PANK2 phosphorylates PanK IEA Rattus norvegicus 10986 R-RNO-199203 https://reactome.org/PathwayBrowser/#/R-RNO-199203 PANK1/3 phosphorylate PanK IEA Rattus norvegicus 10986 R-SCE-196753 https://reactome.org/PathwayBrowser/#/R-SCE-196753 2xPPCS ligates PPanK with Cys IEA Saccharomyces cerevisiae 10986 R-SPO-196753 https://reactome.org/PathwayBrowser/#/R-SPO-196753 2xPPCS ligates PPanK with Cys IEA Schizosaccharomyces pombe 10986 R-SSC-196753 https://reactome.org/PathwayBrowser/#/R-SSC-196753 2xPPCS ligates PPanK with Cys IEA Sus scrofa 10986 R-SSC-196857 https://reactome.org/PathwayBrowser/#/R-SSC-196857 PANK2 phosphorylates PanK IEA Sus scrofa 10986 R-SSC-199203 https://reactome.org/PathwayBrowser/#/R-SSC-199203 PANK1/3 phosphorylate PanK IEA Sus scrofa 10986 R-XTR-196753 https://reactome.org/PathwayBrowser/#/R-XTR-196753 2xPPCS ligates PPanK with Cys IEA Xenopus tropicalis 10986 R-XTR-196857 https://reactome.org/PathwayBrowser/#/R-XTR-196857 PANK2 phosphorylates PanK IEA Xenopus tropicalis 1109 R-SCE-2164813 https://reactome.org/PathwayBrowser/#/R-SCE-2164813 HMPhOH is hydroxylated to MDMQ6H2 by HMPhOH monooxygenase TAS Saccharomyces cerevisiae 1109 R-SCE-2164816 https://reactome.org/PathwayBrowser/#/R-SCE-2164816 MHHB is decarboxylated to HMPhOH by MHHB decarboxylase TAS Saccharomyces cerevisiae 11230 R-BTA-5694485 https://reactome.org/PathwayBrowser/#/R-BTA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Bos taurus 11230 R-CEL-5694485 https://reactome.org/PathwayBrowser/#/R-CEL-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Caenorhabditis elegans 11230 R-CFA-5694485 https://reactome.org/PathwayBrowser/#/R-CFA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Canis familiaris 11230 R-DDI-5694485 https://reactome.org/PathwayBrowser/#/R-DDI-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Dictyostelium discoideum 11230 R-DME-5694485 https://reactome.org/PathwayBrowser/#/R-DME-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Drosophila melanogaster 11230 R-DRE-5694485 https://reactome.org/PathwayBrowser/#/R-DRE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Danio rerio 11230 R-GGA-5694485 https://reactome.org/PathwayBrowser/#/R-GGA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Gallus gallus 11230 R-HSA-5694485 https://reactome.org/PathwayBrowser/#/R-HSA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC TAS Homo sapiens 11230 R-MMU-5694485 https://reactome.org/PathwayBrowser/#/R-MMU-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Mus musculus 11230 R-RNO-5694485 https://reactome.org/PathwayBrowser/#/R-RNO-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Rattus norvegicus 11230 R-SCE-5694485 https://reactome.org/PathwayBrowser/#/R-SCE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Saccharomyces cerevisiae 11230 R-SSC-5694485 https://reactome.org/PathwayBrowser/#/R-SSC-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Sus scrofa 11230 R-XTR-5694485 https://reactome.org/PathwayBrowser/#/R-XTR-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Xenopus tropicalis 114785 R-HSA-1220610 https://reactome.org/PathwayBrowser/#/R-HSA-1220610 Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants TAS Homo sapiens 116962 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 116962 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 116962 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 116962 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 116962 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 116962 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 116962 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 116962 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 116962 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 116962 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 116962 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 116962 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 116962 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 116962 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 116962 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 116962 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 116962 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 116962 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 116962 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 116962 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 116962 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 116962 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 116962 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 116962 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 116962 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 116962 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 116962 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 116962 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 116962 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 116962 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 116962 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 116962 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 116962 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 11750 R-BTA-114553 https://reactome.org/PathwayBrowser/#/R-BTA-114553 Activation of conventional Protein Kinase C IEA Bos taurus 11750 R-BTA-114683 https://reactome.org/PathwayBrowser/#/R-BTA-114683 Phosphorylation of Platelet Sec-1 IEA Bos taurus 11750 R-BTA-114684 https://reactome.org/PathwayBrowser/#/R-BTA-114684 Phosphorylation of Syntaxin-4 IEA Bos taurus 11750 R-BTA-1168373 https://reactome.org/PathwayBrowser/#/R-BTA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Bos taurus 11750 R-BTA-1168635 https://reactome.org/PathwayBrowser/#/R-BTA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Bos taurus 11750 R-BTA-1482636 https://reactome.org/PathwayBrowser/#/R-BTA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Bos taurus 11750 R-BTA-1482691 https://reactome.org/PathwayBrowser/#/R-BTA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Bos taurus 11750 R-BTA-1482771 https://reactome.org/PathwayBrowser/#/R-BTA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Bos taurus 11750 R-BTA-1482776 https://reactome.org/PathwayBrowser/#/R-BTA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Bos taurus 11750 R-BTA-1482897 https://reactome.org/PathwayBrowser/#/R-BTA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Bos taurus 11750 R-BTA-1483089 https://reactome.org/PathwayBrowser/#/R-BTA-1483089 PE is converted to PS by PTDSS2 IEA Bos taurus 11750 R-BTA-1483186 https://reactome.org/PathwayBrowser/#/R-BTA-1483186 PC is converted to PS by PTDSS1 IEA Bos taurus 11750 R-BTA-1602374 https://reactome.org/PathwayBrowser/#/R-BTA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Bos taurus 11750 R-BTA-2197770 https://reactome.org/PathwayBrowser/#/R-BTA-2197770 STAB1 (FEEL-1) binds ligands IEA Bos taurus 11750 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 11750 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 11750 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 11750 R-BTA-2247513 https://reactome.org/PathwayBrowser/#/R-BTA-2247513 STAB1:ligand is endocytosed IEA Bos taurus 11750 R-BTA-416639 https://reactome.org/PathwayBrowser/#/R-BTA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Bos taurus 11750 R-BTA-421007 https://reactome.org/PathwayBrowser/#/R-BTA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Bos taurus 11750 R-BTA-5138432 https://reactome.org/PathwayBrowser/#/R-BTA-5138432 DVL2 is phosphorylated by PKC IEA Bos taurus 11750 R-BTA-5696358 https://reactome.org/PathwayBrowser/#/R-BTA-5696358 TREM,CD300 binds lipids IEA Bos taurus 11750 R-BTA-8867876 https://reactome.org/PathwayBrowser/#/R-BTA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Bos taurus 11750 R-BTA-939763 https://reactome.org/PathwayBrowser/#/R-BTA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Bos taurus 11750 R-BTA-947591 https://reactome.org/PathwayBrowser/#/R-BTA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Bos taurus 11750 R-CEL-114553 https://reactome.org/PathwayBrowser/#/R-CEL-114553 Activation of conventional Protein Kinase C IEA Caenorhabditis elegans 11750 R-CEL-114683 https://reactome.org/PathwayBrowser/#/R-CEL-114683 Phosphorylation of Platelet Sec-1 IEA Caenorhabditis elegans 11750 R-CEL-114684 https://reactome.org/PathwayBrowser/#/R-CEL-114684 Phosphorylation of Syntaxin-4 IEA Caenorhabditis elegans 11750 R-CEL-1168373 https://reactome.org/PathwayBrowser/#/R-CEL-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Caenorhabditis elegans 11750 R-CEL-1482636 https://reactome.org/PathwayBrowser/#/R-CEL-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Caenorhabditis elegans 11750 R-CEL-1482691 https://reactome.org/PathwayBrowser/#/R-CEL-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Caenorhabditis elegans 11750 R-CEL-1482776 https://reactome.org/PathwayBrowser/#/R-CEL-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Caenorhabditis elegans 11750 R-CEL-1483186 https://reactome.org/PathwayBrowser/#/R-CEL-1483186 PC is converted to PS by PTDSS1 IEA Caenorhabditis elegans 11750 R-CEL-1602374 https://reactome.org/PathwayBrowser/#/R-CEL-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Caenorhabditis elegans 11750 R-CEL-5138432 https://reactome.org/PathwayBrowser/#/R-CEL-5138432 DVL2 is phosphorylated by PKC IEA Caenorhabditis elegans 11750 R-CEL-8867876 https://reactome.org/PathwayBrowser/#/R-CEL-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Caenorhabditis elegans 11750 R-CEL-939763 https://reactome.org/PathwayBrowser/#/R-CEL-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Caenorhabditis elegans 11750 R-CEL-947591 https://reactome.org/PathwayBrowser/#/R-CEL-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Caenorhabditis elegans 11750 R-CFA-114553 https://reactome.org/PathwayBrowser/#/R-CFA-114553 Activation of conventional Protein Kinase C IEA Canis familiaris 11750 R-CFA-114683 https://reactome.org/PathwayBrowser/#/R-CFA-114683 Phosphorylation of Platelet Sec-1 IEA Canis familiaris 11750 R-CFA-114684 https://reactome.org/PathwayBrowser/#/R-CFA-114684 Phosphorylation of Syntaxin-4 IEA Canis familiaris 11750 R-CFA-1168373 https://reactome.org/PathwayBrowser/#/R-CFA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Canis familiaris 11750 R-CFA-1168635 https://reactome.org/PathwayBrowser/#/R-CFA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Canis familiaris 11750 R-CFA-1482636 https://reactome.org/PathwayBrowser/#/R-CFA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Canis familiaris 11750 R-CFA-1482691 https://reactome.org/PathwayBrowser/#/R-CFA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Canis familiaris 11750 R-CFA-1482771 https://reactome.org/PathwayBrowser/#/R-CFA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Canis familiaris 11750 R-CFA-1482897 https://reactome.org/PathwayBrowser/#/R-CFA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Canis familiaris 11750 R-CFA-1483089 https://reactome.org/PathwayBrowser/#/R-CFA-1483089 PE is converted to PS by PTDSS2 IEA Canis familiaris 11750 R-CFA-1483186 https://reactome.org/PathwayBrowser/#/R-CFA-1483186 PC is converted to PS by PTDSS1 IEA Canis familiaris 11750 R-CFA-1602374 https://reactome.org/PathwayBrowser/#/R-CFA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Canis familiaris 11750 R-CFA-2197770 https://reactome.org/PathwayBrowser/#/R-CFA-2197770 STAB1 (FEEL-1) binds ligands IEA Canis familiaris 11750 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 11750 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 11750 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 11750 R-CFA-2247513 https://reactome.org/PathwayBrowser/#/R-CFA-2247513 STAB1:ligand is endocytosed IEA Canis familiaris 11750 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 11750 R-CFA-416639 https://reactome.org/PathwayBrowser/#/R-CFA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Canis familiaris 11750 R-CFA-421007 https://reactome.org/PathwayBrowser/#/R-CFA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Canis familiaris 11750 R-CFA-5138432 https://reactome.org/PathwayBrowser/#/R-CFA-5138432 DVL2 is phosphorylated by PKC IEA Canis familiaris 11750 R-CFA-5696358 https://reactome.org/PathwayBrowser/#/R-CFA-5696358 TREM,CD300 binds lipids IEA Canis familiaris 11750 R-CFA-8867876 https://reactome.org/PathwayBrowser/#/R-CFA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Canis familiaris 11750 R-CFA-8869425 https://reactome.org/PathwayBrowser/#/R-CFA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Canis familiaris 11750 R-CFA-8934446 https://reactome.org/PathwayBrowser/#/R-CFA-8934446 Activated PKC phosphorylates SHC1 IEA Canis familiaris 11750 R-CFA-939763 https://reactome.org/PathwayBrowser/#/R-CFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Canis familiaris 11750 R-CFA-947591 https://reactome.org/PathwayBrowser/#/R-CFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Canis familiaris 11750 R-DDI-114553 https://reactome.org/PathwayBrowser/#/R-DDI-114553 Activation of conventional Protein Kinase C IEA Dictyostelium discoideum 11750 R-DDI-114683 https://reactome.org/PathwayBrowser/#/R-DDI-114683 Phosphorylation of Platelet Sec-1 IEA Dictyostelium discoideum 11750 R-DDI-114684 https://reactome.org/PathwayBrowser/#/R-DDI-114684 Phosphorylation of Syntaxin-4 IEA Dictyostelium discoideum 11750 R-DDI-1168373 https://reactome.org/PathwayBrowser/#/R-DDI-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Dictyostelium discoideum 11750 R-DDI-1482636 https://reactome.org/PathwayBrowser/#/R-DDI-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Dictyostelium discoideum 11750 R-DDI-1482691 https://reactome.org/PathwayBrowser/#/R-DDI-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Dictyostelium discoideum 11750 R-DDI-1483089 https://reactome.org/PathwayBrowser/#/R-DDI-1483089 PE is converted to PS by PTDSS2 IEA Dictyostelium discoideum 11750 R-DDI-1483186 https://reactome.org/PathwayBrowser/#/R-DDI-1483186 PC is converted to PS by PTDSS1 IEA Dictyostelium discoideum 11750 R-DDI-8867876 https://reactome.org/PathwayBrowser/#/R-DDI-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Dictyostelium discoideum 11750 R-DDI-939763 https://reactome.org/PathwayBrowser/#/R-DDI-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Dictyostelium discoideum 11750 R-DDI-947591 https://reactome.org/PathwayBrowser/#/R-DDI-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Dictyostelium discoideum 11750 R-DME-114553 https://reactome.org/PathwayBrowser/#/R-DME-114553 Activation of conventional Protein Kinase C IEA Drosophila melanogaster 11750 R-DME-114683 https://reactome.org/PathwayBrowser/#/R-DME-114683 Phosphorylation of Platelet Sec-1 IEA Drosophila melanogaster 11750 R-DME-114684 https://reactome.org/PathwayBrowser/#/R-DME-114684 Phosphorylation of Syntaxin-4 IEA Drosophila melanogaster 11750 R-DME-1168373 https://reactome.org/PathwayBrowser/#/R-DME-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Drosophila melanogaster 11750 R-DME-1482636 https://reactome.org/PathwayBrowser/#/R-DME-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Drosophila melanogaster 11750 R-DME-1482691 https://reactome.org/PathwayBrowser/#/R-DME-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Drosophila melanogaster 11750 R-DME-1482776 https://reactome.org/PathwayBrowser/#/R-DME-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Drosophila melanogaster 11750 R-DME-1483186 https://reactome.org/PathwayBrowser/#/R-DME-1483186 PC is converted to PS by PTDSS1 IEA Drosophila melanogaster 11750 R-DME-1602374 https://reactome.org/PathwayBrowser/#/R-DME-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Drosophila melanogaster 11750 R-DME-416639 https://reactome.org/PathwayBrowser/#/R-DME-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Drosophila melanogaster 11750 R-DME-421007 https://reactome.org/PathwayBrowser/#/R-DME-421007 Endocytosis of Ca impermeable AMPA receptors IEA Drosophila melanogaster 11750 R-DME-8867876 https://reactome.org/PathwayBrowser/#/R-DME-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Drosophila melanogaster 11750 R-DME-8869425 https://reactome.org/PathwayBrowser/#/R-DME-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Drosophila melanogaster 11750 R-DME-8934446 https://reactome.org/PathwayBrowser/#/R-DME-8934446 Activated PKC phosphorylates SHC1 IEA Drosophila melanogaster 11750 R-DME-939763 https://reactome.org/PathwayBrowser/#/R-DME-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Drosophila melanogaster 11750 R-DME-947591 https://reactome.org/PathwayBrowser/#/R-DME-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Drosophila melanogaster 11750 R-DRE-114553 https://reactome.org/PathwayBrowser/#/R-DRE-114553 Activation of conventional Protein Kinase C IEA Danio rerio 11750 R-DRE-114684 https://reactome.org/PathwayBrowser/#/R-DRE-114684 Phosphorylation of Syntaxin-4 IEA Danio rerio 11750 R-DRE-1168373 https://reactome.org/PathwayBrowser/#/R-DRE-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Danio rerio 11750 R-DRE-1482771 https://reactome.org/PathwayBrowser/#/R-DRE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Danio rerio 11750 R-DRE-1482897 https://reactome.org/PathwayBrowser/#/R-DRE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Danio rerio 11750 R-DRE-1483089 https://reactome.org/PathwayBrowser/#/R-DRE-1483089 PE is converted to PS by PTDSS2 IEA Danio rerio 11750 R-DRE-1483186 https://reactome.org/PathwayBrowser/#/R-DRE-1483186 PC is converted to PS by PTDSS1 IEA Danio rerio 11750 R-DRE-1602374 https://reactome.org/PathwayBrowser/#/R-DRE-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Danio rerio 11750 R-DRE-2197770 https://reactome.org/PathwayBrowser/#/R-DRE-2197770 STAB1 (FEEL-1) binds ligands IEA Danio rerio 11750 R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 11750 R-DRE-2247513 https://reactome.org/PathwayBrowser/#/R-DRE-2247513 STAB1:ligand is endocytosed IEA Danio rerio 11750 R-DRE-5696358 https://reactome.org/PathwayBrowser/#/R-DRE-5696358 TREM,CD300 binds lipids IEA Danio rerio 11750 R-DRE-8869425 https://reactome.org/PathwayBrowser/#/R-DRE-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Danio rerio 11750 R-DRE-939763 https://reactome.org/PathwayBrowser/#/R-DRE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Danio rerio 11750 R-DRE-947591 https://reactome.org/PathwayBrowser/#/R-DRE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Danio rerio 11750 R-GGA-114553 https://reactome.org/PathwayBrowser/#/R-GGA-114553 Activation of conventional Protein Kinase C IEA Gallus gallus 11750 R-GGA-114683 https://reactome.org/PathwayBrowser/#/R-GGA-114683 Phosphorylation of Platelet Sec-1 IEA Gallus gallus 11750 R-GGA-1168373 https://reactome.org/PathwayBrowser/#/R-GGA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Gallus gallus 11750 R-GGA-1168635 https://reactome.org/PathwayBrowser/#/R-GGA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Gallus gallus 11750 R-GGA-1482636 https://reactome.org/PathwayBrowser/#/R-GGA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus 11750 R-GGA-1482691 https://reactome.org/PathwayBrowser/#/R-GGA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus 11750 R-GGA-1482771 https://reactome.org/PathwayBrowser/#/R-GGA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Gallus gallus 11750 R-GGA-1482776 https://reactome.org/PathwayBrowser/#/R-GGA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Gallus gallus 11750 R-GGA-1482897 https://reactome.org/PathwayBrowser/#/R-GGA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Gallus gallus 11750 R-GGA-1483089 https://reactome.org/PathwayBrowser/#/R-GGA-1483089 PE is converted to PS by PTDSS2 IEA Gallus gallus 11750 R-GGA-1483186 https://reactome.org/PathwayBrowser/#/R-GGA-1483186 PC is converted to PS by PTDSS1 IEA Gallus gallus 11750 R-GGA-1602374 https://reactome.org/PathwayBrowser/#/R-GGA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Gallus gallus 11750 R-GGA-2197770 https://reactome.org/PathwayBrowser/#/R-GGA-2197770 STAB1 (FEEL-1) binds ligands IEA Gallus gallus 11750 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 11750 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 11750 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 11750 R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus 11750 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 11750 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus 11750 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus 11750 R-GGA-5696358 https://reactome.org/PathwayBrowser/#/R-GGA-5696358 TREM,CD300 binds lipids IEA Gallus gallus 11750 R-GGA-8867876 https://reactome.org/PathwayBrowser/#/R-GGA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Gallus gallus 11750 R-GGA-8869425 https://reactome.org/PathwayBrowser/#/R-GGA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Gallus gallus 11750 R-GGA-8934446 https://reactome.org/PathwayBrowser/#/R-GGA-8934446 Activated PKC phosphorylates SHC1 IEA Gallus gallus 11750 R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus 11750 R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus 11750 R-HSA-114553 https://reactome.org/PathwayBrowser/#/R-HSA-114553 Activation of conventional Protein Kinase C TAS Homo sapiens 11750 R-HSA-114683 https://reactome.org/PathwayBrowser/#/R-HSA-114683 Phosphorylation of Platelet Sec-1 TAS Homo sapiens 11750 R-HSA-114684 https://reactome.org/PathwayBrowser/#/R-HSA-114684 Phosphorylation of Syntaxin-4 TAS Homo sapiens 11750 R-HSA-1168373 https://reactome.org/PathwayBrowser/#/R-HSA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine TAS Homo sapiens 11750 R-HSA-1168635 https://reactome.org/PathwayBrowser/#/R-HSA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 TAS Homo sapiens 11750 R-HSA-1482636 https://reactome.org/PathwayBrowser/#/R-HSA-1482636 1-acyl LPS is acylated to PS by LPSAT TAS Homo sapiens 11750 R-HSA-1482691 https://reactome.org/PathwayBrowser/#/R-HSA-1482691 2-acyl LPS is acylated to PS by LPSAT TAS Homo sapiens 11750 R-HSA-1482771 https://reactome.org/PathwayBrowser/#/R-HSA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] TAS Homo sapiens 11750 R-HSA-1482776 https://reactome.org/PathwayBrowser/#/R-HSA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A TAS Homo sapiens 11750 R-HSA-1482897 https://reactome.org/PathwayBrowser/#/R-HSA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] TAS Homo sapiens 11750 R-HSA-1483089 https://reactome.org/PathwayBrowser/#/R-HSA-1483089 PE is converted to PS by PTDSS2 TAS Homo sapiens 11750 R-HSA-1483170 https://reactome.org/PathwayBrowser/#/R-HSA-1483170 PS transports from the ER membrane to the IM membrane IEA Homo sapiens 11750 R-HSA-1483186 https://reactome.org/PathwayBrowser/#/R-HSA-1483186 PC is converted to PS by PTDSS1 TAS Homo sapiens 11750 R-HSA-1483212 https://reactome.org/PathwayBrowser/#/R-HSA-1483212 PS is decarboxylated to PE by PISD IEA Homo sapiens 11750 R-HSA-1602374 https://reactome.org/PathwayBrowser/#/R-HSA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] TAS Homo sapiens 11750 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 11750 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 11750 R-HSA-2197770 https://reactome.org/PathwayBrowser/#/R-HSA-2197770 STAB1 (FEEL-1) binds ligands TAS Homo sapiens 11750 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 11750 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 11750 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 11750 R-HSA-2247513 https://reactome.org/PathwayBrowser/#/R-HSA-2247513 STAB1:ligand is endocytosed TAS Homo sapiens 11750 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 11750 R-HSA-416639 https://reactome.org/PathwayBrowser/#/R-HSA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites TAS Homo sapiens 11750 R-HSA-421007 https://reactome.org/PathwayBrowser/#/R-HSA-421007 Endocytosis of Ca impermeable AMPA receptors TAS Homo sapiens 11750 R-HSA-4332390 https://reactome.org/PathwayBrowser/#/R-HSA-4332390 Translocation and activation of PKC alpha in response to WNT signaling IEA Homo sapiens 11750 R-HSA-5138432 https://reactome.org/PathwayBrowser/#/R-HSA-5138432 DVL2 is phosphorylated by PKC TAS Homo sapiens 11750 R-HSA-5696358 https://reactome.org/PathwayBrowser/#/R-HSA-5696358 TREM,CD300 binds lipids TAS Homo sapiens 11750 R-HSA-751040 https://reactome.org/PathwayBrowser/#/R-HSA-751040 PKC phosphorylates G alpha (z) IEA Homo sapiens 11750 R-HSA-8867876 https://reactome.org/PathwayBrowser/#/R-HSA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane TAS Homo sapiens 11750 R-HSA-8869425 https://reactome.org/PathwayBrowser/#/R-HSA-8869425 PLA1A hydrolyses PS to 2-acyl LPS TAS Homo sapiens 11750 R-HSA-8934446 https://reactome.org/PathwayBrowser/#/R-HSA-8934446 Activated PKC phosphorylates SHC1 TAS Homo sapiens 11750 R-HSA-8982703 https://reactome.org/PathwayBrowser/#/R-HSA-8982703 PKC binds active G alpha (z) IEA Homo sapiens 11750 R-HSA-8982709 https://reactome.org/PathwayBrowser/#/R-HSA-8982709 G-alpha(z):PKC dissociates to give phosphorylated G alpha (z) IEA Homo sapiens 11750 R-HSA-939763 https://reactome.org/PathwayBrowser/#/R-HSA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane TAS Homo sapiens 11750 R-HSA-947591 https://reactome.org/PathwayBrowser/#/R-HSA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane TAS Homo sapiens 11750 R-MMU-114553 https://reactome.org/PathwayBrowser/#/R-MMU-114553 Activation of conventional Protein Kinase C IEA Mus musculus 11750 R-MMU-114683 https://reactome.org/PathwayBrowser/#/R-MMU-114683 Phosphorylation of Platelet Sec-1 IEA Mus musculus 11750 R-MMU-114684 https://reactome.org/PathwayBrowser/#/R-MMU-114684 Phosphorylation of Syntaxin-4 IEA Mus musculus 11750 R-MMU-1168373 https://reactome.org/PathwayBrowser/#/R-MMU-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Mus musculus 11750 R-MMU-1168635 https://reactome.org/PathwayBrowser/#/R-MMU-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Mus musculus 11750 R-MMU-1482636 https://reactome.org/PathwayBrowser/#/R-MMU-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Mus musculus 11750 R-MMU-1482691 https://reactome.org/PathwayBrowser/#/R-MMU-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Mus musculus 11750 R-MMU-1482771 https://reactome.org/PathwayBrowser/#/R-MMU-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Mus musculus 11750 R-MMU-1482776 https://reactome.org/PathwayBrowser/#/R-MMU-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Mus musculus 11750 R-MMU-1482897 https://reactome.org/PathwayBrowser/#/R-MMU-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Mus musculus 11750 R-MMU-1483089 https://reactome.org/PathwayBrowser/#/R-MMU-1483089 PE is converted to PS by PTDSS2 IEA Mus musculus 11750 R-MMU-1483186 https://reactome.org/PathwayBrowser/#/R-MMU-1483186 PC is converted to PS by PTDSS1 IEA Mus musculus 11750 R-MMU-1602374 https://reactome.org/PathwayBrowser/#/R-MMU-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Mus musculus 11750 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 11750 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 11750 R-MMU-2197770 https://reactome.org/PathwayBrowser/#/R-MMU-2197770 STAB1 (FEEL-1) binds ligands IEA Mus musculus 11750 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 11750 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 11750 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 11750 R-MMU-2247513 https://reactome.org/PathwayBrowser/#/R-MMU-2247513 STAB1:ligand is endocytosed IEA Mus musculus 11750 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 11750 R-MMU-416639 https://reactome.org/PathwayBrowser/#/R-MMU-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Mus musculus 11750 R-MMU-421007 https://reactome.org/PathwayBrowser/#/R-MMU-421007 Endocytosis of Ca impermeable AMPA receptors IEA Mus musculus 11750 R-MMU-5138432 https://reactome.org/PathwayBrowser/#/R-MMU-5138432 DVL2 is phosphorylated by PKC IEA Mus musculus 11750 R-MMU-5696358 https://reactome.org/PathwayBrowser/#/R-MMU-5696358 TREM,CD300 binds lipids IEA Mus musculus 11750 R-MMU-8867876 https://reactome.org/PathwayBrowser/#/R-MMU-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Mus musculus 11750 R-MMU-8869425 https://reactome.org/PathwayBrowser/#/R-MMU-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Mus musculus 11750 R-MMU-8934446 https://reactome.org/PathwayBrowser/#/R-MMU-8934446 Activated PKC phosphorylates SHC1 IEA Mus musculus 11750 R-MMU-939763 https://reactome.org/PathwayBrowser/#/R-MMU-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Mus musculus 11750 R-MMU-947591 https://reactome.org/PathwayBrowser/#/R-MMU-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Mus musculus 11750 R-NUL-804924 https://reactome.org/PathwayBrowser/#/R-NUL-804924 PKC (cow) phosphorylates G alpha z (rat) TAS Bos taurus 11750 R-NUL-8982704 https://reactome.org/PathwayBrowser/#/R-NUL-8982704 PKC (cow) binds G alpha z (rat) TAS Bos taurus 11750 R-NUL-8982712 https://reactome.org/PathwayBrowser/#/R-NUL-8982712 Gz(rat):PKC(cow) dissociates to give phosphorylated G alpha (z) TAS Bos taurus 11750 R-PFA-1482636 https://reactome.org/PathwayBrowser/#/R-PFA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Plasmodium falciparum 11750 R-PFA-1482691 https://reactome.org/PathwayBrowser/#/R-PFA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Plasmodium falciparum 11750 R-PFA-1483089 https://reactome.org/PathwayBrowser/#/R-PFA-1483089 PE is converted to PS by PTDSS2 IEA Plasmodium falciparum 11750 R-PFA-1483186 https://reactome.org/PathwayBrowser/#/R-PFA-1483186 PC is converted to PS by PTDSS1 IEA Plasmodium falciparum 11750 R-PFA-939763 https://reactome.org/PathwayBrowser/#/R-PFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Plasmodium falciparum 11750 R-PFA-947591 https://reactome.org/PathwayBrowser/#/R-PFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Plasmodium falciparum 11750 R-RNO-114553 https://reactome.org/PathwayBrowser/#/R-RNO-114553 Activation of conventional Protein Kinase C IEA Rattus norvegicus 11750 R-RNO-114683 https://reactome.org/PathwayBrowser/#/R-RNO-114683 Phosphorylation of Platelet Sec-1 IEA Rattus norvegicus 11750 R-RNO-114684 https://reactome.org/PathwayBrowser/#/R-RNO-114684 Phosphorylation of Syntaxin-4 IEA Rattus norvegicus 11750 R-RNO-1168373 https://reactome.org/PathwayBrowser/#/R-RNO-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Rattus norvegicus 11750 R-RNO-1168635 https://reactome.org/PathwayBrowser/#/R-RNO-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Rattus norvegicus 11750 R-RNO-1482636 https://reactome.org/PathwayBrowser/#/R-RNO-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Rattus norvegicus 11750 R-RNO-1482691 https://reactome.org/PathwayBrowser/#/R-RNO-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Rattus norvegicus 11750 R-RNO-1482771 https://reactome.org/PathwayBrowser/#/R-RNO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Rattus norvegicus 11750 R-RNO-1482776 https://reactome.org/PathwayBrowser/#/R-RNO-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Rattus norvegicus 11750 R-RNO-1482897 https://reactome.org/PathwayBrowser/#/R-RNO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Rattus norvegicus 11750 R-RNO-1483078 https://reactome.org/PathwayBrowser/#/R-RNO-1483078 PS transports from the ER membrane to the IM membrane TAS Rattus norvegicus 11750 R-RNO-1483089 https://reactome.org/PathwayBrowser/#/R-RNO-1483089 PE is converted to PS by PTDSS2 IEA Rattus norvegicus 11750 R-RNO-1483118 https://reactome.org/PathwayBrowser/#/R-RNO-1483118 PS is decarboxylated to PE by Pisd TAS Rattus norvegicus 11750 R-RNO-1483186 https://reactome.org/PathwayBrowser/#/R-RNO-1483186 PC is converted to PS by PTDSS1 IEA Rattus norvegicus 11750 R-RNO-1602374 https://reactome.org/PathwayBrowser/#/R-RNO-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Rattus norvegicus 11750 R-RNO-2197770 https://reactome.org/PathwayBrowser/#/R-RNO-2197770 STAB1 (FEEL-1) binds ligands IEA Rattus norvegicus 11750 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 11750 R-RNO-2247513 https://reactome.org/PathwayBrowser/#/R-RNO-2247513 STAB1:ligand is endocytosed IEA Rattus norvegicus 11750 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 11750 R-RNO-416639 https://reactome.org/PathwayBrowser/#/R-RNO-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Rattus norvegicus 11750 R-RNO-421007 https://reactome.org/PathwayBrowser/#/R-RNO-421007 Endocytosis of Ca impermeable AMPA receptors IEA Rattus norvegicus 11750 R-RNO-5138432 https://reactome.org/PathwayBrowser/#/R-RNO-5138432 DVL2 is phosphorylated by PKC IEA Rattus norvegicus 11750 R-RNO-5696358 https://reactome.org/PathwayBrowser/#/R-RNO-5696358 TREM,CD300 binds lipids IEA Rattus norvegicus 11750 R-RNO-8867876 https://reactome.org/PathwayBrowser/#/R-RNO-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Rattus norvegicus 11750 R-RNO-8869425 https://reactome.org/PathwayBrowser/#/R-RNO-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Rattus norvegicus 11750 R-RNO-8934446 https://reactome.org/PathwayBrowser/#/R-RNO-8934446 Activated PKC phosphorylates SHC1 IEA Rattus norvegicus 11750 R-RNO-939763 https://reactome.org/PathwayBrowser/#/R-RNO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Rattus norvegicus 11750 R-RNO-947591 https://reactome.org/PathwayBrowser/#/R-RNO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Rattus norvegicus 11750 R-SCE-114553 https://reactome.org/PathwayBrowser/#/R-SCE-114553 Activation of conventional Protein Kinase C IEA Saccharomyces cerevisiae 11750 R-SCE-114683 https://reactome.org/PathwayBrowser/#/R-SCE-114683 Phosphorylation of Platelet Sec-1 IEA Saccharomyces cerevisiae 11750 R-SCE-114684 https://reactome.org/PathwayBrowser/#/R-SCE-114684 Phosphorylation of Syntaxin-4 IEA Saccharomyces cerevisiae 11750 R-SCE-1168373 https://reactome.org/PathwayBrowser/#/R-SCE-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Saccharomyces cerevisiae 11750 R-SCE-1482636 https://reactome.org/PathwayBrowser/#/R-SCE-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Saccharomyces cerevisiae 11750 R-SCE-1482691 https://reactome.org/PathwayBrowser/#/R-SCE-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Saccharomyces cerevisiae 11750 R-SCE-1482771 https://reactome.org/PathwayBrowser/#/R-SCE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Saccharomyces cerevisiae 11750 R-SCE-1482897 https://reactome.org/PathwayBrowser/#/R-SCE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Saccharomyces cerevisiae 11750 R-SCE-8867876 https://reactome.org/PathwayBrowser/#/R-SCE-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Saccharomyces cerevisiae 11750 R-SCE-939763 https://reactome.org/PathwayBrowser/#/R-SCE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Saccharomyces cerevisiae 11750 R-SCE-947591 https://reactome.org/PathwayBrowser/#/R-SCE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Saccharomyces cerevisiae 11750 R-SPO-114553 https://reactome.org/PathwayBrowser/#/R-SPO-114553 Activation of conventional Protein Kinase C IEA Schizosaccharomyces pombe 11750 R-SPO-114683 https://reactome.org/PathwayBrowser/#/R-SPO-114683 Phosphorylation of Platelet Sec-1 IEA Schizosaccharomyces pombe 11750 R-SPO-114684 https://reactome.org/PathwayBrowser/#/R-SPO-114684 Phosphorylation of Syntaxin-4 IEA Schizosaccharomyces pombe 11750 R-SPO-1168373 https://reactome.org/PathwayBrowser/#/R-SPO-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Schizosaccharomyces pombe 11750 R-SPO-1482636 https://reactome.org/PathwayBrowser/#/R-SPO-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Schizosaccharomyces pombe 11750 R-SPO-1482691 https://reactome.org/PathwayBrowser/#/R-SPO-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Schizosaccharomyces pombe 11750 R-SPO-1482771 https://reactome.org/PathwayBrowser/#/R-SPO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Schizosaccharomyces pombe 11750 R-SPO-1482897 https://reactome.org/PathwayBrowser/#/R-SPO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Schizosaccharomyces pombe 11750 R-SPO-8867876 https://reactome.org/PathwayBrowser/#/R-SPO-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Schizosaccharomyces pombe 11750 R-SPO-939763 https://reactome.org/PathwayBrowser/#/R-SPO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Schizosaccharomyces pombe 11750 R-SPO-947591 https://reactome.org/PathwayBrowser/#/R-SPO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Schizosaccharomyces pombe 11750 R-SSC-114553 https://reactome.org/PathwayBrowser/#/R-SSC-114553 Activation of conventional Protein Kinase C IEA Sus scrofa 11750 R-SSC-114683 https://reactome.org/PathwayBrowser/#/R-SSC-114683 Phosphorylation of Platelet Sec-1 IEA Sus scrofa 11750 R-SSC-114684 https://reactome.org/PathwayBrowser/#/R-SSC-114684 Phosphorylation of Syntaxin-4 IEA Sus scrofa 11750 R-SSC-1482636 https://reactome.org/PathwayBrowser/#/R-SSC-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa 11750 R-SSC-1482691 https://reactome.org/PathwayBrowser/#/R-SSC-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa 11750 R-SSC-1482771 https://reactome.org/PathwayBrowser/#/R-SSC-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Sus scrofa 11750 R-SSC-1482776 https://reactome.org/PathwayBrowser/#/R-SSC-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Sus scrofa 11750 R-SSC-1482897 https://reactome.org/PathwayBrowser/#/R-SSC-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Sus scrofa 11750 R-SSC-1483089 https://reactome.org/PathwayBrowser/#/R-SSC-1483089 PE is converted to PS by PTDSS2 IEA Sus scrofa 11750 R-SSC-1483186 https://reactome.org/PathwayBrowser/#/R-SSC-1483186 PC is converted to PS by PTDSS1 IEA Sus scrofa 11750 R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa 11750 R-SSC-2197770 https://reactome.org/PathwayBrowser/#/R-SSC-2197770 STAB1 (FEEL-1) binds ligands IEA Sus scrofa 11750 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 11750 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 11750 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 11750 R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa 11750 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 11750 R-SSC-416639 https://reactome.org/PathwayBrowser/#/R-SSC-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Sus scrofa 11750 R-SSC-421007 https://reactome.org/PathwayBrowser/#/R-SSC-421007 Endocytosis of Ca impermeable AMPA receptors IEA Sus scrofa 11750 R-SSC-5138432 https://reactome.org/PathwayBrowser/#/R-SSC-5138432 DVL2 is phosphorylated by PKC IEA Sus scrofa 11750 R-SSC-5696358 https://reactome.org/PathwayBrowser/#/R-SSC-5696358 TREM,CD300 binds lipids IEA Sus scrofa 11750 R-SSC-8867876 https://reactome.org/PathwayBrowser/#/R-SSC-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Sus scrofa 11750 R-SSC-8869425 https://reactome.org/PathwayBrowser/#/R-SSC-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Sus scrofa 11750 R-SSC-8934446 https://reactome.org/PathwayBrowser/#/R-SSC-8934446 Activated PKC phosphorylates SHC1 IEA Sus scrofa 11750 R-SSC-939763 https://reactome.org/PathwayBrowser/#/R-SSC-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Sus scrofa 11750 R-SSC-947591 https://reactome.org/PathwayBrowser/#/R-SSC-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Sus scrofa 11750 R-XLA-4332392 https://reactome.org/PathwayBrowser/#/R-XLA-4332392 translocation of Xenopus prkca to plasma membrane TAS Xenopus laevis 11750 R-XTR-114553 https://reactome.org/PathwayBrowser/#/R-XTR-114553 Activation of conventional Protein Kinase C IEA Xenopus tropicalis 11750 R-XTR-114683 https://reactome.org/PathwayBrowser/#/R-XTR-114683 Phosphorylation of Platelet Sec-1 IEA Xenopus tropicalis 11750 R-XTR-114684 https://reactome.org/PathwayBrowser/#/R-XTR-114684 Phosphorylation of Syntaxin-4 IEA Xenopus tropicalis 11750 R-XTR-1168373 https://reactome.org/PathwayBrowser/#/R-XTR-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Xenopus tropicalis 11750 R-XTR-1168635 https://reactome.org/PathwayBrowser/#/R-XTR-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Xenopus tropicalis 11750 R-XTR-1482636 https://reactome.org/PathwayBrowser/#/R-XTR-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Xenopus tropicalis 11750 R-XTR-1482691 https://reactome.org/PathwayBrowser/#/R-XTR-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Xenopus tropicalis 11750 R-XTR-1482771 https://reactome.org/PathwayBrowser/#/R-XTR-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Xenopus tropicalis 11750 R-XTR-1482776 https://reactome.org/PathwayBrowser/#/R-XTR-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Xenopus tropicalis 11750 R-XTR-1482897 https://reactome.org/PathwayBrowser/#/R-XTR-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Xenopus tropicalis 11750 R-XTR-1483089 https://reactome.org/PathwayBrowser/#/R-XTR-1483089 PE is converted to PS by PTDSS2 IEA Xenopus tropicalis 11750 R-XTR-1483186 https://reactome.org/PathwayBrowser/#/R-XTR-1483186 PC is converted to PS by PTDSS1 IEA Xenopus tropicalis 11750 R-XTR-1602374 https://reactome.org/PathwayBrowser/#/R-XTR-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Xenopus tropicalis 11750 R-XTR-5138432 https://reactome.org/PathwayBrowser/#/R-XTR-5138432 DVL2 is phosphorylated by PKC IEA Xenopus tropicalis 11750 R-XTR-5696358 https://reactome.org/PathwayBrowser/#/R-XTR-5696358 TREM,CD300 binds lipids IEA Xenopus tropicalis 11750 R-XTR-8867876 https://reactome.org/PathwayBrowser/#/R-XTR-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Xenopus tropicalis 11750 R-XTR-939763 https://reactome.org/PathwayBrowser/#/R-XTR-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Xenopus tropicalis 11750 R-XTR-947591 https://reactome.org/PathwayBrowser/#/R-XTR-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Xenopus tropicalis 11805 R-BTA-508473 https://reactome.org/PathwayBrowser/#/R-BTA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Bos taurus 11805 R-BTA-70881 https://reactome.org/PathwayBrowser/#/R-BTA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Bos taurus 11805 R-BTA-70885 https://reactome.org/PathwayBrowser/#/R-BTA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Bos taurus 11805 R-CEL-508473 https://reactome.org/PathwayBrowser/#/R-CEL-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Caenorhabditis elegans 11805 R-CEL-70881 https://reactome.org/PathwayBrowser/#/R-CEL-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Caenorhabditis elegans 11805 R-CEL-70885 https://reactome.org/PathwayBrowser/#/R-CEL-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Caenorhabditis elegans 11805 R-CFA-508473 https://reactome.org/PathwayBrowser/#/R-CFA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Canis familiaris 11805 R-CFA-70881 https://reactome.org/PathwayBrowser/#/R-CFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Canis familiaris 11805 R-CFA-70885 https://reactome.org/PathwayBrowser/#/R-CFA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Canis familiaris 11805 R-DDI-508473 https://reactome.org/PathwayBrowser/#/R-DDI-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Dictyostelium discoideum 11805 R-DDI-70881 https://reactome.org/PathwayBrowser/#/R-DDI-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Dictyostelium discoideum 11805 R-DDI-70885 https://reactome.org/PathwayBrowser/#/R-DDI-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Dictyostelium discoideum 11805 R-DME-508473 https://reactome.org/PathwayBrowser/#/R-DME-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Drosophila melanogaster 11805 R-DME-70881 https://reactome.org/PathwayBrowser/#/R-DME-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Drosophila melanogaster 11805 R-DME-70885 https://reactome.org/PathwayBrowser/#/R-DME-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Drosophila melanogaster 11805 R-DRE-508473 https://reactome.org/PathwayBrowser/#/R-DRE-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Danio rerio 11805 R-DRE-70881 https://reactome.org/PathwayBrowser/#/R-DRE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Danio rerio 11805 R-DRE-70885 https://reactome.org/PathwayBrowser/#/R-DRE-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Danio rerio 11805 R-GGA-508473 https://reactome.org/PathwayBrowser/#/R-GGA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Gallus gallus 11805 R-GGA-70881 https://reactome.org/PathwayBrowser/#/R-GGA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Gallus gallus 11805 R-GGA-70885 https://reactome.org/PathwayBrowser/#/R-GGA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Gallus gallus 11805 R-HSA-508473 https://reactome.org/PathwayBrowser/#/R-HSA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ TAS Homo sapiens 11805 R-HSA-70881 https://reactome.org/PathwayBrowser/#/R-HSA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA TAS Homo sapiens 11805 R-HSA-70885 https://reactome.org/PathwayBrowser/#/R-HSA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ TAS Homo sapiens 11805 R-MMU-508473 https://reactome.org/PathwayBrowser/#/R-MMU-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Mus musculus 11805 R-MMU-70881 https://reactome.org/PathwayBrowser/#/R-MMU-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Mus musculus 11805 R-MMU-70885 https://reactome.org/PathwayBrowser/#/R-MMU-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Mus musculus 11805 R-PFA-70881 https://reactome.org/PathwayBrowser/#/R-PFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Plasmodium falciparum 11805 R-RNO-508473 https://reactome.org/PathwayBrowser/#/R-RNO-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Rattus norvegicus 11805 R-RNO-70881 https://reactome.org/PathwayBrowser/#/R-RNO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Rattus norvegicus 11805 R-RNO-70885 https://reactome.org/PathwayBrowser/#/R-RNO-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Rattus norvegicus 11805 R-SCE-70881 https://reactome.org/PathwayBrowser/#/R-SCE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Saccharomyces cerevisiae 11805 R-SPO-70881 https://reactome.org/PathwayBrowser/#/R-SPO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Schizosaccharomyces pombe 11805 R-SSC-508473 https://reactome.org/PathwayBrowser/#/R-SSC-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Sus scrofa 11805 R-SSC-70881 https://reactome.org/PathwayBrowser/#/R-SSC-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Sus scrofa 11805 R-SSC-70885 https://reactome.org/PathwayBrowser/#/R-SSC-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Sus scrofa 11805 R-XTR-508473 https://reactome.org/PathwayBrowser/#/R-XTR-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Xenopus tropicalis 11805 R-XTR-70885 https://reactome.org/PathwayBrowser/#/R-XTR-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Xenopus tropicalis 11851 R-BTA-508179 https://reactome.org/PathwayBrowser/#/R-BTA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Bos taurus 11851 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 11851 R-BTA-70724 https://reactome.org/PathwayBrowser/#/R-BTA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Bos taurus 11851 R-CEL-508179 https://reactome.org/PathwayBrowser/#/R-CEL-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Caenorhabditis elegans 11851 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 11851 R-CEL-70724 https://reactome.org/PathwayBrowser/#/R-CEL-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Caenorhabditis elegans 11851 R-CFA-508179 https://reactome.org/PathwayBrowser/#/R-CFA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Canis familiaris 11851 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 11851 R-CFA-70724 https://reactome.org/PathwayBrowser/#/R-CFA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Canis familiaris 11851 R-DDI-508179 https://reactome.org/PathwayBrowser/#/R-DDI-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Dictyostelium discoideum 11851 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 11851 R-DDI-70724 https://reactome.org/PathwayBrowser/#/R-DDI-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Dictyostelium discoideum 11851 R-DME-508179 https://reactome.org/PathwayBrowser/#/R-DME-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Drosophila melanogaster 11851 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 11851 R-DME-70724 https://reactome.org/PathwayBrowser/#/R-DME-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Drosophila melanogaster 11851 R-DRE-508179 https://reactome.org/PathwayBrowser/#/R-DRE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Danio rerio 11851 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 11851 R-DRE-70724 https://reactome.org/PathwayBrowser/#/R-DRE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Danio rerio 11851 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 11851 R-HSA-508179 https://reactome.org/PathwayBrowser/#/R-HSA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] TAS Homo sapiens 11851 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 11851 R-HSA-70724 https://reactome.org/PathwayBrowser/#/R-HSA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] TAS Homo sapiens 11851 R-MMU-508179 https://reactome.org/PathwayBrowser/#/R-MMU-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Mus musculus 11851 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 11851 R-MMU-70724 https://reactome.org/PathwayBrowser/#/R-MMU-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Mus musculus 11851 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 11851 R-RNO-508179 https://reactome.org/PathwayBrowser/#/R-RNO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Rattus norvegicus 11851 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 11851 R-RNO-70724 https://reactome.org/PathwayBrowser/#/R-RNO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Rattus norvegicus 11851 R-SCE-508179 https://reactome.org/PathwayBrowser/#/R-SCE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Saccharomyces cerevisiae 11851 R-SCE-70724 https://reactome.org/PathwayBrowser/#/R-SCE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Saccharomyces cerevisiae 11851 R-SPO-508179 https://reactome.org/PathwayBrowser/#/R-SPO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Schizosaccharomyces pombe 11851 R-SPO-70724 https://reactome.org/PathwayBrowser/#/R-SPO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Schizosaccharomyces pombe 11851 R-SSC-508179 https://reactome.org/PathwayBrowser/#/R-SSC-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Sus scrofa 11851 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 11851 R-SSC-70724 https://reactome.org/PathwayBrowser/#/R-SSC-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Sus scrofa 11851 R-XTR-508179 https://reactome.org/PathwayBrowser/#/R-XTR-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Xenopus tropicalis 11851 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 11851 R-XTR-70724 https://reactome.org/PathwayBrowser/#/R-XTR-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Xenopus tropicalis 11892 R-BTA-73589 https://reactome.org/PathwayBrowser/#/R-BTA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Bos taurus 11892 R-BTA-73591 https://reactome.org/PathwayBrowser/#/R-BTA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Bos taurus 11892 R-CEL-73589 https://reactome.org/PathwayBrowser/#/R-CEL-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Caenorhabditis elegans 11892 R-CEL-73591 https://reactome.org/PathwayBrowser/#/R-CEL-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Caenorhabditis elegans 11892 R-CFA-73589 https://reactome.org/PathwayBrowser/#/R-CFA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Canis familiaris 11892 R-CFA-73591 https://reactome.org/PathwayBrowser/#/R-CFA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Canis familiaris 11892 R-DDI-73589 https://reactome.org/PathwayBrowser/#/R-DDI-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Dictyostelium discoideum 11892 R-DDI-73591 https://reactome.org/PathwayBrowser/#/R-DDI-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Dictyostelium discoideum 11892 R-DME-73589 https://reactome.org/PathwayBrowser/#/R-DME-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Drosophila melanogaster 11892 R-DME-73591 https://reactome.org/PathwayBrowser/#/R-DME-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Drosophila melanogaster 11892 R-DRE-73589 https://reactome.org/PathwayBrowser/#/R-DRE-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Danio rerio 11892 R-DRE-73591 https://reactome.org/PathwayBrowser/#/R-DRE-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Danio rerio 11892 R-GGA-73589 https://reactome.org/PathwayBrowser/#/R-GGA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Gallus gallus 11892 R-GGA-73591 https://reactome.org/PathwayBrowser/#/R-GGA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Gallus gallus 11892 R-HSA-73589 https://reactome.org/PathwayBrowser/#/R-HSA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate TAS Homo sapiens 11892 R-HSA-73591 https://reactome.org/PathwayBrowser/#/R-HSA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 TAS Homo sapiens 11892 R-MMU-73589 https://reactome.org/PathwayBrowser/#/R-MMU-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Mus musculus 11892 R-MMU-73591 https://reactome.org/PathwayBrowser/#/R-MMU-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Mus musculus 11892 R-RNO-73589 https://reactome.org/PathwayBrowser/#/R-RNO-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Rattus norvegicus 11892 R-RNO-73591 https://reactome.org/PathwayBrowser/#/R-RNO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Rattus norvegicus 11892 R-SPO-73591 https://reactome.org/PathwayBrowser/#/R-SPO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Schizosaccharomyces pombe 11892 R-SSC-73589 https://reactome.org/PathwayBrowser/#/R-SSC-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Sus scrofa 11892 R-SSC-73591 https://reactome.org/PathwayBrowser/#/R-SSC-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Sus scrofa 12071 R-BTA-5693977 https://reactome.org/PathwayBrowser/#/R-BTA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Bos taurus 12071 R-BTA-5694137 https://reactome.org/PathwayBrowser/#/R-BTA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Bos taurus 12071 R-BTA-6801328 https://reactome.org/PathwayBrowser/#/R-BTA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Bos taurus 12071 R-CEL-5693977 https://reactome.org/PathwayBrowser/#/R-CEL-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Caenorhabditis elegans 12071 R-CFA-5693977 https://reactome.org/PathwayBrowser/#/R-CFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Canis familiaris 12071 R-CFA-5694137 https://reactome.org/PathwayBrowser/#/R-CFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Canis familiaris 12071 R-CFA-6801328 https://reactome.org/PathwayBrowser/#/R-CFA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Canis familiaris 12071 R-DDI-5693977 https://reactome.org/PathwayBrowser/#/R-DDI-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Dictyostelium discoideum 12071 R-DDI-5694137 https://reactome.org/PathwayBrowser/#/R-DDI-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Dictyostelium discoideum 12071 R-DDI-6801328 https://reactome.org/PathwayBrowser/#/R-DDI-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Dictyostelium discoideum 12071 R-DME-5693977 https://reactome.org/PathwayBrowser/#/R-DME-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Drosophila melanogaster 12071 R-DME-6801328 https://reactome.org/PathwayBrowser/#/R-DME-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Drosophila melanogaster 12071 R-DRE-5693977 https://reactome.org/PathwayBrowser/#/R-DRE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Danio rerio 12071 R-DRE-5694137 https://reactome.org/PathwayBrowser/#/R-DRE-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Danio rerio 12071 R-DRE-6801328 https://reactome.org/PathwayBrowser/#/R-DRE-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Danio rerio 12071 R-GGA-6801328 https://reactome.org/PathwayBrowser/#/R-GGA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Gallus gallus 12071 R-HSA-5693977 https://reactome.org/PathwayBrowser/#/R-HSA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF TAS Homo sapiens 12071 R-HSA-5694137 https://reactome.org/PathwayBrowser/#/R-HSA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser TAS Homo sapiens 12071 R-HSA-6801328 https://reactome.org/PathwayBrowser/#/R-HSA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF TAS Homo sapiens 12071 R-MMU-5693977 https://reactome.org/PathwayBrowser/#/R-MMU-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Mus musculus 12071 R-MMU-5694137 https://reactome.org/PathwayBrowser/#/R-MMU-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Mus musculus 12071 R-MMU-6801328 https://reactome.org/PathwayBrowser/#/R-MMU-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Mus musculus 12071 R-PFA-5693977 https://reactome.org/PathwayBrowser/#/R-PFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Plasmodium falciparum 12071 R-PFA-5694137 https://reactome.org/PathwayBrowser/#/R-PFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Plasmodium falciparum 12071 R-PFA-6801328 https://reactome.org/PathwayBrowser/#/R-PFA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Plasmodium falciparum 12071 R-RNO-5693977 https://reactome.org/PathwayBrowser/#/R-RNO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Rattus norvegicus 12071 R-RNO-5694137 https://reactome.org/PathwayBrowser/#/R-RNO-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Rattus norvegicus 12071 R-RNO-6801328 https://reactome.org/PathwayBrowser/#/R-RNO-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Rattus norvegicus 12071 R-SCE-5693977 https://reactome.org/PathwayBrowser/#/R-SCE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Saccharomyces cerevisiae 12071 R-SCE-6801328 https://reactome.org/PathwayBrowser/#/R-SCE-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Saccharomyces cerevisiae 12071 R-SPO-5693977 https://reactome.org/PathwayBrowser/#/R-SPO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Schizosaccharomyces pombe 12071 R-SPO-6801328 https://reactome.org/PathwayBrowser/#/R-SPO-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Schizosaccharomyces pombe 12071 R-SSC-5693977 https://reactome.org/PathwayBrowser/#/R-SSC-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Sus scrofa 12071 R-SSC-5694137 https://reactome.org/PathwayBrowser/#/R-SSC-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Sus scrofa 12071 R-SSC-6801328 https://reactome.org/PathwayBrowser/#/R-SSC-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Sus scrofa 12071 R-XTR-5693977 https://reactome.org/PathwayBrowser/#/R-XTR-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Xenopus tropicalis 12071 R-XTR-5694137 https://reactome.org/PathwayBrowser/#/R-XTR-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Xenopus tropicalis 12071 R-XTR-6801328 https://reactome.org/PathwayBrowser/#/R-XTR-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Xenopus tropicalis 12387 R-BTA-6787533 https://reactome.org/PathwayBrowser/#/R-BTA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Bos taurus 12387 R-BTA-6787540 https://reactome.org/PathwayBrowser/#/R-BTA-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Bos taurus 12387 R-CEL-6787533 https://reactome.org/PathwayBrowser/#/R-CEL-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Caenorhabditis elegans 12387 R-CEL-6787540 https://reactome.org/PathwayBrowser/#/R-CEL-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Caenorhabditis elegans 12387 R-CFA-6787533 https://reactome.org/PathwayBrowser/#/R-CFA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Canis familiaris 12387 R-CFA-6787540 https://reactome.org/PathwayBrowser/#/R-CFA-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Canis familiaris 12387 R-DDI-6787533 https://reactome.org/PathwayBrowser/#/R-DDI-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Dictyostelium discoideum 12387 R-DDI-6787540 https://reactome.org/PathwayBrowser/#/R-DDI-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Dictyostelium discoideum 12387 R-GGA-6787533 https://reactome.org/PathwayBrowser/#/R-GGA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Gallus gallus 12387 R-HSA-6787533 https://reactome.org/PathwayBrowser/#/R-HSA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc TAS Homo sapiens 12387 R-HSA-6787540 https://reactome.org/PathwayBrowser/#/R-HSA-6787540 FUK phosphorylates beta-Fuc to Fuc1P TAS Homo sapiens 12387 R-MMU-6787533 https://reactome.org/PathwayBrowser/#/R-MMU-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Mus musculus 12387 R-MMU-6787540 https://reactome.org/PathwayBrowser/#/R-MMU-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Mus musculus 12387 R-RNO-6787533 https://reactome.org/PathwayBrowser/#/R-RNO-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Rattus norvegicus 12387 R-RNO-6787540 https://reactome.org/PathwayBrowser/#/R-RNO-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Rattus norvegicus 12387 R-SSC-6787533 https://reactome.org/PathwayBrowser/#/R-SSC-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Sus scrofa 12387 R-SSC-6787540 https://reactome.org/PathwayBrowser/#/R-SSC-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Sus scrofa 12387 R-XTR-6787533 https://reactome.org/PathwayBrowser/#/R-XTR-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Xenopus tropicalis 12387 R-XTR-6787540 https://reactome.org/PathwayBrowser/#/R-XTR-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Xenopus tropicalis 125616 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 125616 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 125616 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 128769 R-BTA-191382 https://reactome.org/PathwayBrowser/#/R-BTA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Bos taurus 128769 R-BTA-191414 https://reactome.org/PathwayBrowser/#/R-BTA-191414 MVD decarboxylates MVA5PP to IPPP IEA Bos taurus 128769 R-BTA-2162253 https://reactome.org/PathwayBrowser/#/R-BTA-2162253 PDSS1,2 ligates FPP to IPPP IEA Bos taurus 128769 R-BTA-4419978 https://reactome.org/PathwayBrowser/#/R-BTA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Bos taurus 128769 R-BTA-9717830 https://reactome.org/PathwayBrowser/#/R-BTA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Bos taurus 128769 R-BTA-9717834 https://reactome.org/PathwayBrowser/#/R-BTA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Bos taurus 128769 R-CEL-191303 https://reactome.org/PathwayBrowser/#/R-CEL-191303 FDPS dimer transfers IPPP to GPP IEA Caenorhabditis elegans 128769 R-CEL-191322 https://reactome.org/PathwayBrowser/#/R-CEL-191322 FDPS dimer transfers IPPP to DMAPP IEA Caenorhabditis elegans 128769 R-CEL-191382 https://reactome.org/PathwayBrowser/#/R-CEL-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Caenorhabditis elegans 128769 R-CEL-191414 https://reactome.org/PathwayBrowser/#/R-CEL-191414 MVD decarboxylates MVA5PP to IPPP IEA Caenorhabditis elegans 128769 R-CEL-4419978 https://reactome.org/PathwayBrowser/#/R-CEL-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Caenorhabditis elegans 128769 R-CFA-191303 https://reactome.org/PathwayBrowser/#/R-CFA-191303 FDPS dimer transfers IPPP to GPP IEA Canis familiaris 128769 R-CFA-191322 https://reactome.org/PathwayBrowser/#/R-CFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Canis familiaris 128769 R-CFA-191382 https://reactome.org/PathwayBrowser/#/R-CFA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Canis familiaris 128769 R-CFA-191414 https://reactome.org/PathwayBrowser/#/R-CFA-191414 MVD decarboxylates MVA5PP to IPPP IEA Canis familiaris 128769 R-CFA-2162253 https://reactome.org/PathwayBrowser/#/R-CFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Canis familiaris 128769 R-CFA-4419978 https://reactome.org/PathwayBrowser/#/R-CFA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Canis familiaris 128769 R-CFA-9717830 https://reactome.org/PathwayBrowser/#/R-CFA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Canis familiaris 128769 R-CFA-9717834 https://reactome.org/PathwayBrowser/#/R-CFA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Canis familiaris 128769 R-DDI-191303 https://reactome.org/PathwayBrowser/#/R-DDI-191303 FDPS dimer transfers IPPP to GPP IEA Dictyostelium discoideum 128769 R-DDI-191322 https://reactome.org/PathwayBrowser/#/R-DDI-191322 FDPS dimer transfers IPPP to DMAPP IEA Dictyostelium discoideum 128769 R-DDI-191382 https://reactome.org/PathwayBrowser/#/R-DDI-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Dictyostelium discoideum 128769 R-DDI-191414 https://reactome.org/PathwayBrowser/#/R-DDI-191414 MVD decarboxylates MVA5PP to IPPP IEA Dictyostelium discoideum 128769 R-DDI-2162253 https://reactome.org/PathwayBrowser/#/R-DDI-2162253 PDSS1,2 ligates FPP to IPPP IEA Dictyostelium discoideum 128769 R-DDI-4419978 https://reactome.org/PathwayBrowser/#/R-DDI-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Dictyostelium discoideum 128769 R-DDI-9717830 https://reactome.org/PathwayBrowser/#/R-DDI-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Dictyostelium discoideum 128769 R-DDI-9717834 https://reactome.org/PathwayBrowser/#/R-DDI-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Dictyostelium discoideum 128769 R-DME-191303 https://reactome.org/PathwayBrowser/#/R-DME-191303 FDPS dimer transfers IPPP to GPP IEA Drosophila melanogaster 128769 R-DME-191322 https://reactome.org/PathwayBrowser/#/R-DME-191322 FDPS dimer transfers IPPP to DMAPP IEA Drosophila melanogaster 128769 R-DME-191382 https://reactome.org/PathwayBrowser/#/R-DME-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Drosophila melanogaster 128769 R-DME-191414 https://reactome.org/PathwayBrowser/#/R-DME-191414 MVD decarboxylates MVA5PP to IPPP IEA Drosophila melanogaster 128769 R-DME-2162253 https://reactome.org/PathwayBrowser/#/R-DME-2162253 PDSS1,2 ligates FPP to IPPP IEA Drosophila melanogaster 128769 R-DME-4419978 https://reactome.org/PathwayBrowser/#/R-DME-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Drosophila melanogaster 128769 R-DME-9717830 https://reactome.org/PathwayBrowser/#/R-DME-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Drosophila melanogaster 128769 R-DME-9717834 https://reactome.org/PathwayBrowser/#/R-DME-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Drosophila melanogaster 128769 R-DRE-191303 https://reactome.org/PathwayBrowser/#/R-DRE-191303 FDPS dimer transfers IPPP to GPP IEA Danio rerio 128769 R-DRE-191322 https://reactome.org/PathwayBrowser/#/R-DRE-191322 FDPS dimer transfers IPPP to DMAPP IEA Danio rerio 128769 R-DRE-191414 https://reactome.org/PathwayBrowser/#/R-DRE-191414 MVD decarboxylates MVA5PP to IPPP IEA Danio rerio 128769 R-DRE-2162253 https://reactome.org/PathwayBrowser/#/R-DRE-2162253 PDSS1,2 ligates FPP to IPPP IEA Danio rerio 128769 R-DRE-4419978 https://reactome.org/PathwayBrowser/#/R-DRE-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Danio rerio 128769 R-GGA-191303 https://reactome.org/PathwayBrowser/#/R-GGA-191303 FDPS dimer transfers IPPP to GPP IEA Gallus gallus 128769 R-GGA-191322 https://reactome.org/PathwayBrowser/#/R-GGA-191322 FDPS dimer transfers IPPP to DMAPP IEA Gallus gallus 128769 R-GGA-191382 https://reactome.org/PathwayBrowser/#/R-GGA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Gallus gallus 128769 R-GGA-191414 https://reactome.org/PathwayBrowser/#/R-GGA-191414 MVD decarboxylates MVA5PP to IPPP IEA Gallus gallus 128769 R-GGA-2162253 https://reactome.org/PathwayBrowser/#/R-GGA-2162253 PDSS1,2 ligates FPP to IPPP IEA Gallus gallus 128769 R-GGA-4419978 https://reactome.org/PathwayBrowser/#/R-GGA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Gallus gallus 128769 R-GGA-9717830 https://reactome.org/PathwayBrowser/#/R-GGA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Gallus gallus 128769 R-GGA-9717834 https://reactome.org/PathwayBrowser/#/R-GGA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Gallus gallus 128769 R-HSA-191303 https://reactome.org/PathwayBrowser/#/R-HSA-191303 FDPS dimer transfers IPPP to GPP TAS Homo sapiens 128769 R-HSA-191322 https://reactome.org/PathwayBrowser/#/R-HSA-191322 FDPS dimer transfers IPPP to DMAPP TAS Homo sapiens 128769 R-HSA-191382 https://reactome.org/PathwayBrowser/#/R-HSA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate TAS Homo sapiens 128769 R-HSA-191414 https://reactome.org/PathwayBrowser/#/R-HSA-191414 MVD decarboxylates MVA5PP to IPPP TAS Homo sapiens 128769 R-HSA-2162253 https://reactome.org/PathwayBrowser/#/R-HSA-2162253 PDSS1,2 ligates FPP to IPPP TAS Homo sapiens 128769 R-HSA-4419978 https://reactome.org/PathwayBrowser/#/R-HSA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP TAS Homo sapiens 128769 R-HSA-4755545 https://reactome.org/PathwayBrowser/#/R-HSA-4755545 Defective DHDDS does not elongate E,E-FPP TAS Homo sapiens 128769 R-HSA-9717830 https://reactome.org/PathwayBrowser/#/R-HSA-9717830 GGPS1 hexamer transfers IPPP to GPP TAS Homo sapiens 128769 R-HSA-9717834 https://reactome.org/PathwayBrowser/#/R-HSA-9717834 GGPS1 hexamer transfers IPPP to DMAPP TAS Homo sapiens 128769 R-MMU-191303 https://reactome.org/PathwayBrowser/#/R-MMU-191303 FDPS dimer transfers IPPP to GPP IEA Mus musculus 128769 R-MMU-191322 https://reactome.org/PathwayBrowser/#/R-MMU-191322 FDPS dimer transfers IPPP to DMAPP IEA Mus musculus 128769 R-MMU-191382 https://reactome.org/PathwayBrowser/#/R-MMU-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Mus musculus 128769 R-MMU-191414 https://reactome.org/PathwayBrowser/#/R-MMU-191414 MVD decarboxylates MVA5PP to IPPP IEA Mus musculus 128769 R-MMU-2162253 https://reactome.org/PathwayBrowser/#/R-MMU-2162253 PDSS1,2 ligates FPP to IPPP IEA Mus musculus 128769 R-MMU-4419978 https://reactome.org/PathwayBrowser/#/R-MMU-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Mus musculus 128769 R-MMU-9717830 https://reactome.org/PathwayBrowser/#/R-MMU-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Mus musculus 128769 R-MMU-9717834 https://reactome.org/PathwayBrowser/#/R-MMU-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Mus musculus 128769 R-PFA-191303 https://reactome.org/PathwayBrowser/#/R-PFA-191303 FDPS dimer transfers IPPP to GPP IEA Plasmodium falciparum 128769 R-PFA-191322 https://reactome.org/PathwayBrowser/#/R-PFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Plasmodium falciparum 128769 R-PFA-2162253 https://reactome.org/PathwayBrowser/#/R-PFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Plasmodium falciparum 128769 R-RNO-191303 https://reactome.org/PathwayBrowser/#/R-RNO-191303 FDPS dimer transfers IPPP to GPP IEA Rattus norvegicus 128769 R-RNO-191322 https://reactome.org/PathwayBrowser/#/R-RNO-191322 FDPS dimer transfers IPPP to DMAPP IEA Rattus norvegicus 128769 R-RNO-191382 https://reactome.org/PathwayBrowser/#/R-RNO-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Rattus norvegicus 128769 R-RNO-191414 https://reactome.org/PathwayBrowser/#/R-RNO-191414 MVD decarboxylates MVA5PP to IPPP IEA Rattus norvegicus 128769 R-RNO-2162253 https://reactome.org/PathwayBrowser/#/R-RNO-2162253 PDSS1,2 ligates FPP to IPPP IEA Rattus norvegicus 128769 R-RNO-4419978 https://reactome.org/PathwayBrowser/#/R-RNO-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Rattus norvegicus 128769 R-RNO-9717830 https://reactome.org/PathwayBrowser/#/R-RNO-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Rattus norvegicus 128769 R-RNO-9717834 https://reactome.org/PathwayBrowser/#/R-RNO-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Rattus norvegicus 128769 R-SCE-191303 https://reactome.org/PathwayBrowser/#/R-SCE-191303 FDPS dimer transfers IPPP to GPP IEA Saccharomyces cerevisiae 128769 R-SCE-191322 https://reactome.org/PathwayBrowser/#/R-SCE-191322 FDPS dimer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 128769 R-SCE-191382 https://reactome.org/PathwayBrowser/#/R-SCE-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Saccharomyces cerevisiae 128769 R-SCE-191414 https://reactome.org/PathwayBrowser/#/R-SCE-191414 MVD decarboxylates MVA5PP to IPPP IEA Saccharomyces cerevisiae 128769 R-SCE-2162253 https://reactome.org/PathwayBrowser/#/R-SCE-2162253 PDSS1,2 ligates FPP to IPPP IEA Saccharomyces cerevisiae 128769 R-SCE-4419978 https://reactome.org/PathwayBrowser/#/R-SCE-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Saccharomyces cerevisiae 128769 R-SCE-9717830 https://reactome.org/PathwayBrowser/#/R-SCE-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Saccharomyces cerevisiae 128769 R-SCE-9717834 https://reactome.org/PathwayBrowser/#/R-SCE-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 128769 R-SPO-191303 https://reactome.org/PathwayBrowser/#/R-SPO-191303 FDPS dimer transfers IPPP to GPP IEA Schizosaccharomyces pombe 128769 R-SPO-191322 https://reactome.org/PathwayBrowser/#/R-SPO-191322 FDPS dimer transfers IPPP to DMAPP IEA Schizosaccharomyces pombe 128769 R-SPO-191382 https://reactome.org/PathwayBrowser/#/R-SPO-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Schizosaccharomyces pombe 128769 R-SPO-191414 https://reactome.org/PathwayBrowser/#/R-SPO-191414 MVD decarboxylates MVA5PP to IPPP IEA Schizosaccharomyces pombe 128769 R-SPO-2162253 https://reactome.org/PathwayBrowser/#/R-SPO-2162253 PDSS1,2 ligates FPP to IPPP IEA Schizosaccharomyces pombe 128769 R-SPO-4419978 https://reactome.org/PathwayBrowser/#/R-SPO-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Schizosaccharomyces pombe 128769 R-SSC-191303 https://reactome.org/PathwayBrowser/#/R-SSC-191303 FDPS dimer transfers IPPP to GPP IEA Sus scrofa 128769 R-SSC-191322 https://reactome.org/PathwayBrowser/#/R-SSC-191322 FDPS dimer transfers IPPP to DMAPP IEA Sus scrofa 128769 R-SSC-191382 https://reactome.org/PathwayBrowser/#/R-SSC-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Sus scrofa 128769 R-SSC-191414 https://reactome.org/PathwayBrowser/#/R-SSC-191414 MVD decarboxylates MVA5PP to IPPP IEA Sus scrofa 128769 R-SSC-2162253 https://reactome.org/PathwayBrowser/#/R-SSC-2162253 PDSS1,2 ligates FPP to IPPP IEA Sus scrofa 128769 R-SSC-4419978 https://reactome.org/PathwayBrowser/#/R-SSC-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Sus scrofa 128769 R-SSC-9717830 https://reactome.org/PathwayBrowser/#/R-SSC-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Sus scrofa 128769 R-SSC-9717834 https://reactome.org/PathwayBrowser/#/R-SSC-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Sus scrofa 128769 R-XTR-191382 https://reactome.org/PathwayBrowser/#/R-XTR-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Xenopus tropicalis 128769 R-XTR-191414 https://reactome.org/PathwayBrowser/#/R-XTR-191414 MVD decarboxylates MVA5PP to IPPP IEA Xenopus tropicalis 128769 R-XTR-2162253 https://reactome.org/PathwayBrowser/#/R-XTR-2162253 PDSS1,2 ligates FPP to IPPP IEA Xenopus tropicalis 128769 R-XTR-9717830 https://reactome.org/PathwayBrowser/#/R-XTR-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Xenopus tropicalis 128769 R-XTR-9717834 https://reactome.org/PathwayBrowser/#/R-XTR-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Xenopus tropicalis 1294 R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 1294 R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 1294 R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 1294 R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 1294 R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 1294 R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 1294 R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 1294 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 1294 R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 1294 R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 1294 R-HSA-5580269 https://reactome.org/PathwayBrowser/#/R-HSA-5580269 Defective CYP11A1 does not cleave 20a,22b-DHCHOL TAS Homo sapiens 1294 R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 1294 R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 1294 R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 1294 R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 1294 R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 1294 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 1294 R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 1294 R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 1301 R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 1301 R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 1301 R-BTA-4720432 https://reactome.org/PathwayBrowser/#/R-BTA-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Bos taurus 1301 R-BTA-4720446 https://reactome.org/PathwayBrowser/#/R-BTA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Bos taurus 1301 R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 1301 R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 1301 R-DME-4720432 https://reactome.org/PathwayBrowser/#/R-DME-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Drosophila melanogaster 1301 R-DME-4720446 https://reactome.org/PathwayBrowser/#/R-DME-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Drosophila melanogaster 1301 R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 1301 R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 1301 R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 1301 R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 1301 R-GGA-4720446 https://reactome.org/PathwayBrowser/#/R-GGA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Gallus gallus 1301 R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 1301 R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 1301 R-HSA-4720432 https://reactome.org/PathwayBrowser/#/R-HSA-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 TAS Homo sapiens 1301 R-HSA-4720446 https://reactome.org/PathwayBrowser/#/R-HSA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 TAS Homo sapiens 1301 R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 1301 R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 1301 R-MMU-4720432 https://reactome.org/PathwayBrowser/#/R-MMU-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Mus musculus 1301 R-MMU-4720446 https://reactome.org/PathwayBrowser/#/R-MMU-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Mus musculus 1301 R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 1301 R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 1301 R-RNO-4720432 https://reactome.org/PathwayBrowser/#/R-RNO-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Rattus norvegicus 1301 R-RNO-4720446 https://reactome.org/PathwayBrowser/#/R-RNO-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Rattus norvegicus 1301 R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 1301 R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 1301 R-SSC-4720432 https://reactome.org/PathwayBrowser/#/R-SSC-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Sus scrofa 1301 R-SSC-4720446 https://reactome.org/PathwayBrowser/#/R-SSC-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Sus scrofa 1301 R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 1301 R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 13115 R-BTA-5661256 https://reactome.org/PathwayBrowser/#/R-BTA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Bos taurus 13115 R-BTA-5661290 https://reactome.org/PathwayBrowser/#/R-BTA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Bos taurus 13115 R-CEL-5661256 https://reactome.org/PathwayBrowser/#/R-CEL-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Caenorhabditis elegans 13115 R-CEL-5661290 https://reactome.org/PathwayBrowser/#/R-CEL-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Caenorhabditis elegans 13115 R-CFA-5661256 https://reactome.org/PathwayBrowser/#/R-CFA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Canis familiaris 13115 R-CFA-5661290 https://reactome.org/PathwayBrowser/#/R-CFA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Canis familiaris 13115 R-DDI-5661256 https://reactome.org/PathwayBrowser/#/R-DDI-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Dictyostelium discoideum 13115 R-DME-5661256 https://reactome.org/PathwayBrowser/#/R-DME-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Drosophila melanogaster 13115 R-DME-5661290 https://reactome.org/PathwayBrowser/#/R-DME-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Drosophila melanogaster 13115 R-DRE-5661256 https://reactome.org/PathwayBrowser/#/R-DRE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Danio rerio 13115 R-DRE-5661290 https://reactome.org/PathwayBrowser/#/R-DRE-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Danio rerio 13115 R-GGA-5661256 https://reactome.org/PathwayBrowser/#/R-GGA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Gallus gallus 13115 R-GGA-5661290 https://reactome.org/PathwayBrowser/#/R-GGA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Gallus gallus 13115 R-HSA-5661256 https://reactome.org/PathwayBrowser/#/R-HSA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate TAS Homo sapiens 13115 R-HSA-5661290 https://reactome.org/PathwayBrowser/#/R-HSA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate TAS Homo sapiens 13115 R-MMU-5661256 https://reactome.org/PathwayBrowser/#/R-MMU-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Mus musculus 13115 R-MMU-5661290 https://reactome.org/PathwayBrowser/#/R-MMU-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Mus musculus 13115 R-RNO-5661256 https://reactome.org/PathwayBrowser/#/R-RNO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Rattus norvegicus 13115 R-RNO-5661290 https://reactome.org/PathwayBrowser/#/R-RNO-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Rattus norvegicus 13115 R-SCE-5661256 https://reactome.org/PathwayBrowser/#/R-SCE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Saccharomyces cerevisiae 13115 R-SPO-5661256 https://reactome.org/PathwayBrowser/#/R-SPO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Schizosaccharomyces pombe 13115 R-SSC-5661256 https://reactome.org/PathwayBrowser/#/R-SSC-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Sus scrofa 13115 R-SSC-5661290 https://reactome.org/PathwayBrowser/#/R-SSC-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Sus scrofa 13115 R-XTR-5661256 https://reactome.org/PathwayBrowser/#/R-XTR-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Xenopus tropicalis 13115 R-XTR-5661290 https://reactome.org/PathwayBrowser/#/R-XTR-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Xenopus tropicalis 131617 R-BTA-9023968 https://reactome.org/PathwayBrowser/#/R-BTA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Bos taurus 131617 R-CFA-9023968 https://reactome.org/PathwayBrowser/#/R-CFA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Canis familiaris 131617 R-DME-9023968 https://reactome.org/PathwayBrowser/#/R-DME-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Drosophila melanogaster 131617 R-DRE-9023968 https://reactome.org/PathwayBrowser/#/R-DRE-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Danio rerio 131617 R-GGA-9023968 https://reactome.org/PathwayBrowser/#/R-GGA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Gallus gallus 131617 R-HSA-9023968 https://reactome.org/PathwayBrowser/#/R-HSA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 TAS Homo sapiens 131617 R-MMU-9023968 https://reactome.org/PathwayBrowser/#/R-MMU-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Mus musculus 131617 R-RNO-9023968 https://reactome.org/PathwayBrowser/#/R-RNO-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Rattus norvegicus 131617 R-SSC-9023968 https://reactome.org/PathwayBrowser/#/R-SSC-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Sus scrofa 131617 R-XTR-9023968 https://reactome.org/PathwayBrowser/#/R-XTR-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Xenopus tropicalis 13166 R-HSA-2408509 https://reactome.org/PathwayBrowser/#/R-HSA-2408509 Sec-tRNA(Sec) binds to EEFSEC:GTP IEA Homo sapiens 13166 R-HSA-2408529 https://reactome.org/PathwayBrowser/#/R-HSA-2408529 Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome IEA Homo sapiens 13166 R-HSA-2408555 https://reactome.org/PathwayBrowser/#/R-HSA-2408555 Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer TAS Homo sapiens 13166 R-HSA-5333615 https://reactome.org/PathwayBrowser/#/R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC IEA Homo sapiens 13166 R-MMU-2408515 https://reactome.org/PathwayBrowser/#/R-MMU-2408515 Sec-tRNA(Sec) binds to Eefsec:GTP TAS Mus musculus 13166 R-RNO-2408535 https://reactome.org/PathwayBrowser/#/R-RNO-2408535 Sec-tRNA(Sec):Eefsec:GTP binds to Rpl30 TAS Rattus norvegicus 13166 R-RNO-5333610 https://reactome.org/PathwayBrowser/#/R-RNO-5333610 Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec-tRNA(Sec):Eefsec:GTP is hydrolysed to Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec and Eefsec:GDP by Eefsec TAS Rattus norvegicus 13170 R-HSA-2408507 https://reactome.org/PathwayBrowser/#/R-HSA-2408507 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK IEA Homo sapiens 13170 R-HSA-2408526 https://reactome.org/PathwayBrowser/#/R-HSA-2408526 tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer TAS Homo sapiens 13170 R-MMU-2408505 https://reactome.org/PathwayBrowser/#/R-MMU-2408505 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by Pstk TAS Mus musculus 131727 R-HSA-1222526 https://reactome.org/PathwayBrowser/#/R-HSA-1222526 AhpC reduces peroxidated lipids TAS Homo sapiens 131825 R-HSA-6789114 https://reactome.org/PathwayBrowser/#/R-HSA-6789114 Hydroxyl radical reacts with the base and sugar moiety of DNA TAS Homo sapiens 131882 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 13193 R-BTA-2995334 https://reactome.org/PathwayBrowser/#/R-BTA-2995334 COX15 transforms heme O to heme A IEA Bos taurus 13193 R-BTA-6797961 https://reactome.org/PathwayBrowser/#/R-BTA-6797961 CHDH oxidises Cho to BETALD IEA Bos taurus 13193 R-CEL-2995334 https://reactome.org/PathwayBrowser/#/R-CEL-2995334 COX15 transforms heme O to heme A IEA Caenorhabditis elegans 13193 R-CEL-6797961 https://reactome.org/PathwayBrowser/#/R-CEL-6797961 CHDH oxidises Cho to BETALD IEA Caenorhabditis elegans 13193 R-CFA-2995334 https://reactome.org/PathwayBrowser/#/R-CFA-2995334 COX15 transforms heme O to heme A IEA Canis familiaris 13193 R-CFA-6797961 https://reactome.org/PathwayBrowser/#/R-CFA-6797961 CHDH oxidises Cho to BETALD IEA Canis familiaris 13193 R-DDI-2995334 https://reactome.org/PathwayBrowser/#/R-DDI-2995334 COX15 transforms heme O to heme A IEA Dictyostelium discoideum 13193 R-DDI-6797961 https://reactome.org/PathwayBrowser/#/R-DDI-6797961 CHDH oxidises Cho to BETALD IEA Dictyostelium discoideum 13193 R-DME-2995334 https://reactome.org/PathwayBrowser/#/R-DME-2995334 COX15 transforms heme O to heme A IEA Drosophila melanogaster 13193 R-DME-6797961 https://reactome.org/PathwayBrowser/#/R-DME-6797961 CHDH oxidises Cho to BETALD IEA Drosophila melanogaster 13193 R-GGA-2995334 https://reactome.org/PathwayBrowser/#/R-GGA-2995334 COX15 transforms heme O to heme A IEA Gallus gallus 13193 R-GGA-6797961 https://reactome.org/PathwayBrowser/#/R-GGA-6797961 CHDH oxidises Cho to BETALD IEA Gallus gallus 13193 R-HSA-2995334 https://reactome.org/PathwayBrowser/#/R-HSA-2995334 COX15 transforms heme O to heme A TAS Homo sapiens 13193 R-HSA-6797961 https://reactome.org/PathwayBrowser/#/R-HSA-6797961 CHDH oxidises Cho to BETALD TAS Homo sapiens 13193 R-MMU-2995334 https://reactome.org/PathwayBrowser/#/R-MMU-2995334 COX15 transforms heme O to heme A IEA Mus musculus 13193 R-MMU-6797961 https://reactome.org/PathwayBrowser/#/R-MMU-6797961 CHDH oxidises Cho to BETALD IEA Mus musculus 13193 R-PFA-2995334 https://reactome.org/PathwayBrowser/#/R-PFA-2995334 COX15 transforms heme O to heme A IEA Plasmodium falciparum 13193 R-RNO-2995334 https://reactome.org/PathwayBrowser/#/R-RNO-2995334 COX15 transforms heme O to heme A IEA Rattus norvegicus 13193 R-RNO-6797961 https://reactome.org/PathwayBrowser/#/R-RNO-6797961 CHDH oxidises Cho to BETALD IEA Rattus norvegicus 13193 R-SCE-2995334 https://reactome.org/PathwayBrowser/#/R-SCE-2995334 COX15 transforms heme O to heme A IEA Saccharomyces cerevisiae 13193 R-SPO-2995334 https://reactome.org/PathwayBrowser/#/R-SPO-2995334 COX15 transforms heme O to heme A IEA Schizosaccharomyces pombe 13193 R-SSC-2995334 https://reactome.org/PathwayBrowser/#/R-SSC-2995334 COX15 transforms heme O to heme A IEA Sus scrofa 13193 R-SSC-6797961 https://reactome.org/PathwayBrowser/#/R-SSC-6797961 CHDH oxidises Cho to BETALD IEA Sus scrofa 13193 R-XTR-2995334 https://reactome.org/PathwayBrowser/#/R-XTR-2995334 COX15 transforms heme O to heme A IEA Xenopus tropicalis 132041 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 132041 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 132041 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 132041 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 132041 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 132041 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 132041 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 132041 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 132041 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 132041 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 132041 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 132041 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 132041 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 132041 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 132041 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 132041 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 132041 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 132041 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 132041 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 132041 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 132041 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 132041 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 132041 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 132041 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 132041 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 132041 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 132041 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 132041 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 132041 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 132041 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 132041 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 132041 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 132041 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 132228 R-BTA-9024983 https://reactome.org/PathwayBrowser/#/R-BTA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Bos taurus 132228 R-BTA-9024993 https://reactome.org/PathwayBrowser/#/R-BTA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Bos taurus 132228 R-BTA-9026777 https://reactome.org/PathwayBrowser/#/R-BTA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Bos taurus 132228 R-BTA-9026780 https://reactome.org/PathwayBrowser/#/R-BTA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Bos taurus 132228 R-CFA-9024983 https://reactome.org/PathwayBrowser/#/R-CFA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Canis familiaris 132228 R-CFA-9024993 https://reactome.org/PathwayBrowser/#/R-CFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Canis familiaris 132228 R-CFA-9026777 https://reactome.org/PathwayBrowser/#/R-CFA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Canis familiaris 132228 R-CFA-9026780 https://reactome.org/PathwayBrowser/#/R-CFA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Canis familiaris 132228 R-DDI-9024983 https://reactome.org/PathwayBrowser/#/R-DDI-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Dictyostelium discoideum 132228 R-DDI-9024993 https://reactome.org/PathwayBrowser/#/R-DDI-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Dictyostelium discoideum 132228 R-DDI-9026780 https://reactome.org/PathwayBrowser/#/R-DDI-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Dictyostelium discoideum 132228 R-DRE-9024983 https://reactome.org/PathwayBrowser/#/R-DRE-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Danio rerio 132228 R-DRE-9024993 https://reactome.org/PathwayBrowser/#/R-DRE-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Danio rerio 132228 R-DRE-9026777 https://reactome.org/PathwayBrowser/#/R-DRE-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Danio rerio 132228 R-GGA-9024993 https://reactome.org/PathwayBrowser/#/R-GGA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Gallus gallus 132228 R-GGA-9026777 https://reactome.org/PathwayBrowser/#/R-GGA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Gallus gallus 132228 R-GGA-9026780 https://reactome.org/PathwayBrowser/#/R-GGA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Gallus gallus 132228 R-HSA-9024973 https://reactome.org/PathwayBrowser/#/R-HSA-9024973 Epoxide hydrolase hydrolyses 13(S),14(S)-epoxy-DHA to MaR1 TAS Homo sapiens 132228 R-HSA-9024983 https://reactome.org/PathwayBrowser/#/R-HSA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA TAS Homo sapiens 132228 R-HSA-9024993 https://reactome.org/PathwayBrowser/#/R-HSA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 TAS Homo sapiens 132228 R-HSA-9026544 https://reactome.org/PathwayBrowser/#/R-HSA-9026544 Non-enzymatic hydrolysis hydrolyses 13(S),14(S)-epoxy-DHA to 7-epi-MaR1 TAS Homo sapiens 132228 R-HSA-9026777 https://reactome.org/PathwayBrowser/#/R-HSA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 TAS Homo sapiens 132228 R-HSA-9026780 https://reactome.org/PathwayBrowser/#/R-HSA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 TAS Homo sapiens 132228 R-MMU-9024983 https://reactome.org/PathwayBrowser/#/R-MMU-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Mus musculus 132228 R-MMU-9024993 https://reactome.org/PathwayBrowser/#/R-MMU-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Mus musculus 132228 R-MMU-9026777 https://reactome.org/PathwayBrowser/#/R-MMU-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Mus musculus 132228 R-MMU-9026780 https://reactome.org/PathwayBrowser/#/R-MMU-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Mus musculus 132228 R-PFA-9024993 https://reactome.org/PathwayBrowser/#/R-PFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Plasmodium falciparum 132228 R-RNO-9024983 https://reactome.org/PathwayBrowser/#/R-RNO-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Rattus norvegicus 132228 R-RNO-9024993 https://reactome.org/PathwayBrowser/#/R-RNO-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Rattus norvegicus 132228 R-RNO-9026777 https://reactome.org/PathwayBrowser/#/R-RNO-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Rattus norvegicus 132228 R-RNO-9026780 https://reactome.org/PathwayBrowser/#/R-RNO-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Rattus norvegicus 132228 R-SSC-9024983 https://reactome.org/PathwayBrowser/#/R-SSC-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Sus scrofa 132228 R-SSC-9024993 https://reactome.org/PathwayBrowser/#/R-SSC-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Sus scrofa 132228 R-SSC-9026777 https://reactome.org/PathwayBrowser/#/R-SSC-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Sus scrofa 132228 R-SSC-9026780 https://reactome.org/PathwayBrowser/#/R-SSC-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Sus scrofa 132228 R-XTR-9024993 https://reactome.org/PathwayBrowser/#/R-XTR-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Xenopus tropicalis 132228 R-XTR-9026777 https://reactome.org/PathwayBrowser/#/R-XTR-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Xenopus tropicalis 132228 R-XTR-9026780 https://reactome.org/PathwayBrowser/#/R-XTR-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Xenopus tropicalis 132797 R-BTA-9024766 https://reactome.org/PathwayBrowser/#/R-BTA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Bos taurus 132797 R-CFA-9024766 https://reactome.org/PathwayBrowser/#/R-CFA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Canis familiaris 132797 R-DME-9024766 https://reactome.org/PathwayBrowser/#/R-DME-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Drosophila melanogaster 132797 R-DRE-9024766 https://reactome.org/PathwayBrowser/#/R-DRE-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Danio rerio 132797 R-GGA-9024766 https://reactome.org/PathwayBrowser/#/R-GGA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Gallus gallus 132797 R-HSA-9024766 https://reactome.org/PathwayBrowser/#/R-HSA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 TAS Homo sapiens 132797 R-MMU-9024766 https://reactome.org/PathwayBrowser/#/R-MMU-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Mus musculus 132797 R-RNO-9024766 https://reactome.org/PathwayBrowser/#/R-RNO-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Rattus norvegicus 132797 R-SSC-9024766 https://reactome.org/PathwayBrowser/#/R-SSC-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Sus scrofa 132797 R-XTR-9024766 https://reactome.org/PathwayBrowser/#/R-XTR-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Xenopus tropicalis 132800 R-BTA-9024766 https://reactome.org/PathwayBrowser/#/R-BTA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Bos taurus 132800 R-CFA-9024766 https://reactome.org/PathwayBrowser/#/R-CFA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Canis familiaris 132800 R-DME-9024766 https://reactome.org/PathwayBrowser/#/R-DME-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Drosophila melanogaster 132800 R-DRE-9024766 https://reactome.org/PathwayBrowser/#/R-DRE-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Danio rerio 132800 R-GGA-9024766 https://reactome.org/PathwayBrowser/#/R-GGA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Gallus gallus 132800 R-HSA-9024766 https://reactome.org/PathwayBrowser/#/R-HSA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 TAS Homo sapiens 132800 R-MMU-9024766 https://reactome.org/PathwayBrowser/#/R-MMU-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Mus musculus 132800 R-RNO-9024766 https://reactome.org/PathwayBrowser/#/R-RNO-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Rattus norvegicus 132800 R-SSC-9024766 https://reactome.org/PathwayBrowser/#/R-SSC-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Sus scrofa 132800 R-XTR-9024766 https://reactome.org/PathwayBrowser/#/R-XTR-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Xenopus tropicalis 132801 R-BTA-9018858 https://reactome.org/PathwayBrowser/#/R-BTA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Bos taurus 132801 R-BTA-9018868 https://reactome.org/PathwayBrowser/#/R-BTA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Bos taurus 132801 R-BTA-9020610 https://reactome.org/PathwayBrowser/#/R-BTA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Bos taurus 132801 R-CEL-9018868 https://reactome.org/PathwayBrowser/#/R-CEL-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Caenorhabditis elegans 132801 R-CFA-9018858 https://reactome.org/PathwayBrowser/#/R-CFA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Canis familiaris 132801 R-CFA-9018868 https://reactome.org/PathwayBrowser/#/R-CFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Canis familiaris 132801 R-CFA-9020610 https://reactome.org/PathwayBrowser/#/R-CFA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Canis familiaris 132801 R-DDI-9018858 https://reactome.org/PathwayBrowser/#/R-DDI-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Dictyostelium discoideum 132801 R-DDI-9020610 https://reactome.org/PathwayBrowser/#/R-DDI-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Dictyostelium discoideum 132801 R-DRE-9018858 https://reactome.org/PathwayBrowser/#/R-DRE-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Danio rerio 132801 R-DRE-9020610 https://reactome.org/PathwayBrowser/#/R-DRE-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Danio rerio 132801 R-GGA-9018858 https://reactome.org/PathwayBrowser/#/R-GGA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Gallus gallus 132801 R-GGA-9018868 https://reactome.org/PathwayBrowser/#/R-GGA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Gallus gallus 132801 R-HSA-9018858 https://reactome.org/PathwayBrowser/#/R-HSA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE TAS Homo sapiens 132801 R-HSA-9018868 https://reactome.org/PathwayBrowser/#/R-HSA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE TAS Homo sapiens 132801 R-HSA-9020610 https://reactome.org/PathwayBrowser/#/R-HSA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 TAS Homo sapiens 132801 R-MMU-9018858 https://reactome.org/PathwayBrowser/#/R-MMU-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Mus musculus 132801 R-MMU-9018868 https://reactome.org/PathwayBrowser/#/R-MMU-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Mus musculus 132801 R-MMU-9020610 https://reactome.org/PathwayBrowser/#/R-MMU-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Mus musculus 132801 R-PFA-9018868 https://reactome.org/PathwayBrowser/#/R-PFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Plasmodium falciparum 132801 R-RNO-9018858 https://reactome.org/PathwayBrowser/#/R-RNO-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Rattus norvegicus 132801 R-RNO-9018868 https://reactome.org/PathwayBrowser/#/R-RNO-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Rattus norvegicus 132801 R-RNO-9020610 https://reactome.org/PathwayBrowser/#/R-RNO-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Rattus norvegicus 132801 R-SSC-9018858 https://reactome.org/PathwayBrowser/#/R-SSC-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Sus scrofa 132801 R-SSC-9018868 https://reactome.org/PathwayBrowser/#/R-SSC-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Sus scrofa 132801 R-SSC-9020610 https://reactome.org/PathwayBrowser/#/R-SSC-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Sus scrofa 132801 R-XTR-9018858 https://reactome.org/PathwayBrowser/#/R-XTR-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Xenopus tropicalis 132802 R-BTA-9018858 https://reactome.org/PathwayBrowser/#/R-BTA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Bos taurus 132802 R-BTA-9018859 https://reactome.org/PathwayBrowser/#/R-BTA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Bos taurus 132802 R-CFA-9018858 https://reactome.org/PathwayBrowser/#/R-CFA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Canis familiaris 132802 R-CFA-9018859 https://reactome.org/PathwayBrowser/#/R-CFA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Canis familiaris 132802 R-DDI-9018858 https://reactome.org/PathwayBrowser/#/R-DDI-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Dictyostelium discoideum 132802 R-DDI-9018859 https://reactome.org/PathwayBrowser/#/R-DDI-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Dictyostelium discoideum 132802 R-DRE-9018858 https://reactome.org/PathwayBrowser/#/R-DRE-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Danio rerio 132802 R-DRE-9018859 https://reactome.org/PathwayBrowser/#/R-DRE-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Danio rerio 132802 R-GGA-9018858 https://reactome.org/PathwayBrowser/#/R-GGA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Gallus gallus 132802 R-GGA-9018859 https://reactome.org/PathwayBrowser/#/R-GGA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Gallus gallus 132802 R-HSA-9018858 https://reactome.org/PathwayBrowser/#/R-HSA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE TAS Homo sapiens 132802 R-HSA-9018859 https://reactome.org/PathwayBrowser/#/R-HSA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE TAS Homo sapiens 132802 R-HSA-9018867 https://reactome.org/PathwayBrowser/#/R-HSA-9018867 5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2 TAS Homo sapiens 132802 R-MMU-9018858 https://reactome.org/PathwayBrowser/#/R-MMU-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Mus musculus 132802 R-MMU-9018859 https://reactome.org/PathwayBrowser/#/R-MMU-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Mus musculus 132802 R-RNO-9018858 https://reactome.org/PathwayBrowser/#/R-RNO-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Rattus norvegicus 132802 R-RNO-9018859 https://reactome.org/PathwayBrowser/#/R-RNO-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Rattus norvegicus 132802 R-SSC-9018858 https://reactome.org/PathwayBrowser/#/R-SSC-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Sus scrofa 132802 R-SSC-9018859 https://reactome.org/PathwayBrowser/#/R-SSC-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Sus scrofa 132802 R-XTR-9018858 https://reactome.org/PathwayBrowser/#/R-XTR-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Xenopus tropicalis 132802 R-XTR-9018859 https://reactome.org/PathwayBrowser/#/R-XTR-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Xenopus tropicalis 132873 R-BTA-8932633 https://reactome.org/PathwayBrowser/#/R-BTA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Bos taurus 132873 R-CEL-8932633 https://reactome.org/PathwayBrowser/#/R-CEL-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Caenorhabditis elegans 132873 R-CFA-8932633 https://reactome.org/PathwayBrowser/#/R-CFA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Canis familiaris 132873 R-DRE-8932633 https://reactome.org/PathwayBrowser/#/R-DRE-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Danio rerio 132873 R-GGA-8932633 https://reactome.org/PathwayBrowser/#/R-GGA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Gallus gallus 132873 R-HSA-8932633 https://reactome.org/PathwayBrowser/#/R-HSA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE TAS Homo sapiens 132873 R-MMU-8932633 https://reactome.org/PathwayBrowser/#/R-MMU-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Mus musculus 132873 R-RNO-8932633 https://reactome.org/PathwayBrowser/#/R-RNO-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Rattus norvegicus 132873 R-SSC-8932633 https://reactome.org/PathwayBrowser/#/R-SSC-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Sus scrofa 132873 R-XTR-8932633 https://reactome.org/PathwayBrowser/#/R-XTR-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Xenopus tropicalis 132908 R-BTA-9018863 https://reactome.org/PathwayBrowser/#/R-BTA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Bos taurus 132908 R-BTA-9018894 https://reactome.org/PathwayBrowser/#/R-BTA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Bos taurus 132908 R-CFA-9018863 https://reactome.org/PathwayBrowser/#/R-CFA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Canis familiaris 132908 R-CFA-9018894 https://reactome.org/PathwayBrowser/#/R-CFA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Canis familiaris 132908 R-DDI-9018863 https://reactome.org/PathwayBrowser/#/R-DDI-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Dictyostelium discoideum 132908 R-DDI-9018894 https://reactome.org/PathwayBrowser/#/R-DDI-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Dictyostelium discoideum 132908 R-DRE-9018863 https://reactome.org/PathwayBrowser/#/R-DRE-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Danio rerio 132908 R-DRE-9018894 https://reactome.org/PathwayBrowser/#/R-DRE-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Danio rerio 132908 R-GGA-9018863 https://reactome.org/PathwayBrowser/#/R-GGA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Gallus gallus 132908 R-GGA-9018894 https://reactome.org/PathwayBrowser/#/R-GGA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Gallus gallus 132908 R-HSA-9018863 https://reactome.org/PathwayBrowser/#/R-HSA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE TAS Homo sapiens 132908 R-HSA-9018894 https://reactome.org/PathwayBrowser/#/R-HSA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE TAS Homo sapiens 132908 R-HSA-9018901 https://reactome.org/PathwayBrowser/#/R-HSA-9018901 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HpEPE to 18(R)-RvE2 TAS Homo sapiens 132908 R-MMU-9018863 https://reactome.org/PathwayBrowser/#/R-MMU-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Mus musculus 132908 R-MMU-9018894 https://reactome.org/PathwayBrowser/#/R-MMU-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Mus musculus 132908 R-RNO-9018863 https://reactome.org/PathwayBrowser/#/R-RNO-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Rattus norvegicus 132908 R-RNO-9018894 https://reactome.org/PathwayBrowser/#/R-RNO-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Rattus norvegicus 132908 R-SSC-9018863 https://reactome.org/PathwayBrowser/#/R-SSC-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Sus scrofa 132908 R-SSC-9018894 https://reactome.org/PathwayBrowser/#/R-SSC-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Sus scrofa 132908 R-XTR-9018863 https://reactome.org/PathwayBrowser/#/R-XTR-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Xenopus tropicalis 132908 R-XTR-9018894 https://reactome.org/PathwayBrowser/#/R-XTR-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Xenopus tropicalis 132962 R-BTA-158546 https://reactome.org/PathwayBrowser/#/R-BTA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Bos taurus 132962 R-BTA-9753278 https://reactome.org/PathwayBrowser/#/R-BTA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 132962 R-BTA-9753283 https://reactome.org/PathwayBrowser/#/R-BTA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 132962 R-CEL-158546 https://reactome.org/PathwayBrowser/#/R-CEL-158546 UGTs glucuronate APAP to APAP-GlcA IEA Caenorhabditis elegans 132962 R-CEL-9753278 https://reactome.org/PathwayBrowser/#/R-CEL-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 132962 R-CEL-9753283 https://reactome.org/PathwayBrowser/#/R-CEL-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 132962 R-CFA-158546 https://reactome.org/PathwayBrowser/#/R-CFA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Canis familiaris 132962 R-CFA-9753278 https://reactome.org/PathwayBrowser/#/R-CFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 132962 R-CFA-9753283 https://reactome.org/PathwayBrowser/#/R-CFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 132962 R-DDI-158546 https://reactome.org/PathwayBrowser/#/R-DDI-158546 UGTs glucuronate APAP to APAP-GlcA IEA Dictyostelium discoideum 132962 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 132962 R-DDI-9753278 https://reactome.org/PathwayBrowser/#/R-DDI-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 132962 R-DDI-9753283 https://reactome.org/PathwayBrowser/#/R-DDI-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 132962 R-DME-158546 https://reactome.org/PathwayBrowser/#/R-DME-158546 UGTs glucuronate APAP to APAP-GlcA IEA Drosophila melanogaster 132962 R-DME-9753278 https://reactome.org/PathwayBrowser/#/R-DME-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 132962 R-DME-9753283 https://reactome.org/PathwayBrowser/#/R-DME-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 132962 R-DRE-158546 https://reactome.org/PathwayBrowser/#/R-DRE-158546 UGTs glucuronate APAP to APAP-GlcA IEA Danio rerio 132962 R-DRE-9753278 https://reactome.org/PathwayBrowser/#/R-DRE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 132962 R-DRE-9753283 https://reactome.org/PathwayBrowser/#/R-DRE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 132962 R-GGA-158546 https://reactome.org/PathwayBrowser/#/R-GGA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Gallus gallus 132962 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 132962 R-GGA-9753278 https://reactome.org/PathwayBrowser/#/R-GGA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 132962 R-GGA-9753283 https://reactome.org/PathwayBrowser/#/R-GGA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 132962 R-HSA-158546 https://reactome.org/PathwayBrowser/#/R-HSA-158546 UGTs glucuronate APAP to APAP-GlcA TAS Homo sapiens 132962 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 132962 R-HSA-9753278 https://reactome.org/PathwayBrowser/#/R-HSA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 132962 R-HSA-9753283 https://reactome.org/PathwayBrowser/#/R-HSA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 132962 R-MMU-158546 https://reactome.org/PathwayBrowser/#/R-MMU-158546 UGTs glucuronate APAP to APAP-GlcA IEA Mus musculus 132962 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 132962 R-MMU-9753278 https://reactome.org/PathwayBrowser/#/R-MMU-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 132962 R-MMU-9753283 https://reactome.org/PathwayBrowser/#/R-MMU-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 132962 R-PFA-9753278 https://reactome.org/PathwayBrowser/#/R-PFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 132962 R-PFA-9753283 https://reactome.org/PathwayBrowser/#/R-PFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 132962 R-RNO-158546 https://reactome.org/PathwayBrowser/#/R-RNO-158546 UGTs glucuronate APAP to APAP-GlcA IEA Rattus norvegicus 132962 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 132962 R-RNO-9753278 https://reactome.org/PathwayBrowser/#/R-RNO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 132962 R-RNO-9753283 https://reactome.org/PathwayBrowser/#/R-RNO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 132962 R-SCE-9753278 https://reactome.org/PathwayBrowser/#/R-SCE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 132962 R-SCE-9753283 https://reactome.org/PathwayBrowser/#/R-SCE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 132962 R-SPO-9753278 https://reactome.org/PathwayBrowser/#/R-SPO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 132962 R-SPO-9753283 https://reactome.org/PathwayBrowser/#/R-SPO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 132962 R-SSC-158546 https://reactome.org/PathwayBrowser/#/R-SSC-158546 UGTs glucuronate APAP to APAP-GlcA IEA Sus scrofa 132962 R-SSC-9753278 https://reactome.org/PathwayBrowser/#/R-SSC-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 132962 R-SSC-9753283 https://reactome.org/PathwayBrowser/#/R-SSC-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 132962 R-XTR-9753278 https://reactome.org/PathwayBrowser/#/R-XTR-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 132962 R-XTR-9753283 https://reactome.org/PathwayBrowser/#/R-XTR-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 132986 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 132986 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 132986 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 132986 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 132986 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 132986 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 132986 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 132986 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 132986 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 132986 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 132986 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 132986 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 132986 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 132986 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 132986 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 132986 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 132986 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 132986 R-HSA-9665304 https://reactome.org/PathwayBrowser/#/R-HSA-9665304 ERBB2 T862A does not bind sapitinib TAS Homo sapiens 132986 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 132986 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 132986 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 132986 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 132986 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 132986 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 133015 R-BTA-5617138 https://reactome.org/PathwayBrowser/#/R-BTA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Bos taurus 133015 R-BTA-9638090 https://reactome.org/PathwayBrowser/#/R-BTA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Bos taurus 133015 R-CFA-5617138 https://reactome.org/PathwayBrowser/#/R-CFA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Canis familiaris 133015 R-CFA-9638090 https://reactome.org/PathwayBrowser/#/R-CFA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Canis familiaris 133015 R-DRE-5617138 https://reactome.org/PathwayBrowser/#/R-DRE-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Danio rerio 133015 R-DRE-9638090 https://reactome.org/PathwayBrowser/#/R-DRE-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Danio rerio 133015 R-HSA-5617138 https://reactome.org/PathwayBrowser/#/R-HSA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA TAS Homo sapiens 133015 R-HSA-9638090 https://reactome.org/PathwayBrowser/#/R-HSA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA TAS Homo sapiens 133015 R-MMU-5617138 https://reactome.org/PathwayBrowser/#/R-MMU-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Mus musculus 133015 R-MMU-9638090 https://reactome.org/PathwayBrowser/#/R-MMU-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Mus musculus 133015 R-RNO-5617138 https://reactome.org/PathwayBrowser/#/R-RNO-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Rattus norvegicus 133015 R-RNO-9638090 https://reactome.org/PathwayBrowser/#/R-RNO-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Rattus norvegicus 133015 R-SSC-5617138 https://reactome.org/PathwayBrowser/#/R-SSC-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Sus scrofa 133015 R-SSC-9638090 https://reactome.org/PathwayBrowser/#/R-SSC-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Sus scrofa 133015 R-XTR-5617138 https://reactome.org/PathwayBrowser/#/R-XTR-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Xenopus tropicalis 133015 R-XTR-9638090 https://reactome.org/PathwayBrowser/#/R-XTR-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Xenopus tropicalis 133066 R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 133066 R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 133066 R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 133066 R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 133066 R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 133066 R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 133066 R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 133066 R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 133066 R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 133066 R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 133066 R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 133066 R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 133066 R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 133066 R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 133066 R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 133067 R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 133067 R-BTA-9753632 https://reactome.org/PathwayBrowser/#/R-BTA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Bos taurus 133067 R-BTA-9753676 https://reactome.org/PathwayBrowser/#/R-BTA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Bos taurus 133067 R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 133067 R-CEL-9753632 https://reactome.org/PathwayBrowser/#/R-CEL-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Caenorhabditis elegans 133067 R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 133067 R-CFA-9753632 https://reactome.org/PathwayBrowser/#/R-CFA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Canis familiaris 133067 R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 133067 R-DDI-9753632 https://reactome.org/PathwayBrowser/#/R-DDI-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Dictyostelium discoideum 133067 R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 133067 R-DME-9753632 https://reactome.org/PathwayBrowser/#/R-DME-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Drosophila melanogaster 133067 R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 133067 R-DRE-9753632 https://reactome.org/PathwayBrowser/#/R-DRE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Danio rerio 133067 R-DRE-9753676 https://reactome.org/PathwayBrowser/#/R-DRE-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Danio rerio 133067 R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 133067 R-GGA-9753632 https://reactome.org/PathwayBrowser/#/R-GGA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Gallus gallus 133067 R-GGA-9753676 https://reactome.org/PathwayBrowser/#/R-GGA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Gallus gallus 133067 R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 133067 R-HSA-9753632 https://reactome.org/PathwayBrowser/#/R-HSA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly TAS Homo sapiens 133067 R-HSA-9753676 https://reactome.org/PathwayBrowser/#/R-HSA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer TAS Homo sapiens 133067 R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 133067 R-MMU-9753632 https://reactome.org/PathwayBrowser/#/R-MMU-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Mus musculus 133067 R-MMU-9753676 https://reactome.org/PathwayBrowser/#/R-MMU-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Mus musculus 133067 R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 133067 R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 133067 R-RNO-9753632 https://reactome.org/PathwayBrowser/#/R-RNO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Rattus norvegicus 133067 R-RNO-9753676 https://reactome.org/PathwayBrowser/#/R-RNO-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Rattus norvegicus 133067 R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 133067 R-SCE-9753632 https://reactome.org/PathwayBrowser/#/R-SCE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Saccharomyces cerevisiae 133067 R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 133067 R-SPO-9753632 https://reactome.org/PathwayBrowser/#/R-SPO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Schizosaccharomyces pombe 133067 R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 133067 R-SSC-9753632 https://reactome.org/PathwayBrowser/#/R-SSC-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Sus scrofa 133067 R-SSC-9753676 https://reactome.org/PathwayBrowser/#/R-SSC-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Sus scrofa 133067 R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 133067 R-XTR-9753632 https://reactome.org/PathwayBrowser/#/R-XTR-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Xenopus tropicalis 133202 R-BTA-8938073 https://reactome.org/PathwayBrowser/#/R-BTA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Bos taurus 133202 R-CFA-8938073 https://reactome.org/PathwayBrowser/#/R-CFA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Canis familiaris 133202 R-DDI-8938073 https://reactome.org/PathwayBrowser/#/R-DDI-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Dictyostelium discoideum 133202 R-DME-8938073 https://reactome.org/PathwayBrowser/#/R-DME-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Drosophila melanogaster 133202 R-DRE-8938073 https://reactome.org/PathwayBrowser/#/R-DRE-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Danio rerio 133202 R-GGA-8938073 https://reactome.org/PathwayBrowser/#/R-GGA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Gallus gallus 133202 R-HSA-8938073 https://reactome.org/PathwayBrowser/#/R-HSA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) TAS Homo sapiens 133202 R-MMU-8938073 https://reactome.org/PathwayBrowser/#/R-MMU-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Mus musculus 133202 R-RNO-8938073 https://reactome.org/PathwayBrowser/#/R-RNO-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Rattus norvegicus 133202 R-SSC-8938073 https://reactome.org/PathwayBrowser/#/R-SSC-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Sus scrofa 133202 R-XTR-8938073 https://reactome.org/PathwayBrowser/#/R-XTR-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Xenopus tropicalis 133203 R-BTA-8938073 https://reactome.org/PathwayBrowser/#/R-BTA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Bos taurus 133203 R-CFA-8938073 https://reactome.org/PathwayBrowser/#/R-CFA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Canis familiaris 133203 R-DDI-8938073 https://reactome.org/PathwayBrowser/#/R-DDI-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Dictyostelium discoideum 133203 R-DME-8938073 https://reactome.org/PathwayBrowser/#/R-DME-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Drosophila melanogaster 133203 R-DRE-8938073 https://reactome.org/PathwayBrowser/#/R-DRE-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Danio rerio 133203 R-GGA-8938073 https://reactome.org/PathwayBrowser/#/R-GGA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Gallus gallus 133203 R-HSA-8938073 https://reactome.org/PathwayBrowser/#/R-HSA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) TAS Homo sapiens 133203 R-MMU-8938073 https://reactome.org/PathwayBrowser/#/R-MMU-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Mus musculus 133203 R-RNO-8938073 https://reactome.org/PathwayBrowser/#/R-RNO-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Rattus norvegicus 133203 R-SSC-8938073 https://reactome.org/PathwayBrowser/#/R-SSC-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Sus scrofa 133203 R-XTR-8938073 https://reactome.org/PathwayBrowser/#/R-XTR-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Xenopus tropicalis 133334 R-BTA-9833777 https://reactome.org/PathwayBrowser/#/R-BTA-9833777 PKR binds activating host RNA IEA Bos taurus 133334 R-CEL-9833777 https://reactome.org/PathwayBrowser/#/R-CEL-9833777 PKR binds activating host RNA IEA Caenorhabditis elegans 133334 R-CFA-9833777 https://reactome.org/PathwayBrowser/#/R-CFA-9833777 PKR binds activating host RNA IEA Canis familiaris 133334 R-DME-9833777 https://reactome.org/PathwayBrowser/#/R-DME-9833777 PKR binds activating host RNA IEA Drosophila melanogaster 133334 R-DRE-9833777 https://reactome.org/PathwayBrowser/#/R-DRE-9833777 PKR binds activating host RNA IEA Danio rerio 133334 R-GGA-9833777 https://reactome.org/PathwayBrowser/#/R-GGA-9833777 PKR binds activating host RNA IEA Gallus gallus 133334 R-HSA-9833723 https://reactome.org/PathwayBrowser/#/R-HSA-9833723 PKR forms a dimer TAS Homo sapiens 133334 R-HSA-9833777 https://reactome.org/PathwayBrowser/#/R-HSA-9833777 PKR binds activating host RNA TAS Homo sapiens 133334 R-MMU-9833777 https://reactome.org/PathwayBrowser/#/R-MMU-9833777 PKR binds activating host RNA IEA Mus musculus 133334 R-RNO-9833777 https://reactome.org/PathwayBrowser/#/R-RNO-9833777 PKR binds activating host RNA IEA Rattus norvegicus 133334 R-SSC-9833777 https://reactome.org/PathwayBrowser/#/R-SSC-9833777 PKR binds activating host RNA IEA Sus scrofa 133334 R-XTR-9833777 https://reactome.org/PathwayBrowser/#/R-XTR-9833777 PKR binds activating host RNA IEA Xenopus tropicalis 133435 R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 133435 R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 133435 R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 133435 R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 133435 R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 133435 R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 133435 R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 133435 R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 133435 R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 133435 R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 133435 R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 133435 R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 133435 R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 133435 R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 133435 R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 133438 R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 133438 R-BTA-9753676 https://reactome.org/PathwayBrowser/#/R-BTA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Bos taurus 133438 R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 133438 R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 133438 R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 133438 R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 133438 R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 133438 R-DRE-9753676 https://reactome.org/PathwayBrowser/#/R-DRE-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Danio rerio 133438 R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 133438 R-GGA-9753676 https://reactome.org/PathwayBrowser/#/R-GGA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Gallus gallus 133438 R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 133438 R-HSA-9753676 https://reactome.org/PathwayBrowser/#/R-HSA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer TAS Homo sapiens 133438 R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 133438 R-MMU-9753676 https://reactome.org/PathwayBrowser/#/R-MMU-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Mus musculus 133438 R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 133438 R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 133438 R-RNO-9753676 https://reactome.org/PathwayBrowser/#/R-RNO-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Rattus norvegicus 133438 R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 133438 R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 133438 R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 133438 R-SSC-9753676 https://reactome.org/PathwayBrowser/#/R-SSC-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Sus scrofa 133438 R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 133667 R-CFA-8941701 https://reactome.org/PathwayBrowser/#/R-CFA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Canis familiaris 133667 R-DDI-8941701 https://reactome.org/PathwayBrowser/#/R-DDI-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Dictyostelium discoideum 133667 R-GGA-8941701 https://reactome.org/PathwayBrowser/#/R-GGA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Gallus gallus 133667 R-HSA-8941701 https://reactome.org/PathwayBrowser/#/R-HSA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN TAS Homo sapiens 133667 R-MMU-8941701 https://reactome.org/PathwayBrowser/#/R-MMU-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Mus musculus 133667 R-RNO-8941701 https://reactome.org/PathwayBrowser/#/R-RNO-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Rattus norvegicus 133817 R-BTA-8937419 https://reactome.org/PathwayBrowser/#/R-BTA-8937419 CBR3 reduces DOX to DOXOL IEA Bos taurus 133817 R-CFA-8937419 https://reactome.org/PathwayBrowser/#/R-CFA-8937419 CBR3 reduces DOX to DOXOL IEA Canis familiaris 133817 R-DRE-8937419 https://reactome.org/PathwayBrowser/#/R-DRE-8937419 CBR3 reduces DOX to DOXOL IEA Danio rerio 133817 R-GGA-8937419 https://reactome.org/PathwayBrowser/#/R-GGA-8937419 CBR3 reduces DOX to DOXOL IEA Gallus gallus 133817 R-HSA-8937419 https://reactome.org/PathwayBrowser/#/R-HSA-8937419 CBR3 reduces DOX to DOXOL TAS Homo sapiens 133817 R-MMU-8937419 https://reactome.org/PathwayBrowser/#/R-MMU-8937419 CBR3 reduces DOX to DOXOL IEA Mus musculus 133817 R-RNO-8937419 https://reactome.org/PathwayBrowser/#/R-RNO-8937419 CBR3 reduces DOX to DOXOL IEA Rattus norvegicus 133817 R-SSC-8937419 https://reactome.org/PathwayBrowser/#/R-SSC-8937419 CBR3 reduces DOX to DOXOL IEA Sus scrofa 133817 R-XTR-8937419 https://reactome.org/PathwayBrowser/#/R-XTR-8937419 CBR3 reduces DOX to DOXOL IEA Xenopus tropicalis 133907 R-BTA-8855490 https://reactome.org/PathwayBrowser/#/R-BTA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Bos taurus 133907 R-CEL-8855490 https://reactome.org/PathwayBrowser/#/R-CEL-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Caenorhabditis elegans 133907 R-CFA-8855490 https://reactome.org/PathwayBrowser/#/R-CFA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Canis familiaris 133907 R-DDI-8855490 https://reactome.org/PathwayBrowser/#/R-DDI-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Dictyostelium discoideum 133907 R-DME-8855490 https://reactome.org/PathwayBrowser/#/R-DME-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Drosophila melanogaster 133907 R-GGA-8855490 https://reactome.org/PathwayBrowser/#/R-GGA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Gallus gallus 133907 R-HSA-8855490 https://reactome.org/PathwayBrowser/#/R-HSA-8855490 Lactoperoxidase (LPO) produces OSCN- TAS Homo sapiens 133907 R-HSA-8941411 https://reactome.org/PathwayBrowser/#/R-HSA-8941411 OSCN- reacts with Cys residues TAS Homo sapiens 133907 R-MMU-8855490 https://reactome.org/PathwayBrowser/#/R-MMU-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Mus musculus 133907 R-RNO-8855490 https://reactome.org/PathwayBrowser/#/R-RNO-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Rattus norvegicus 133907 R-SSC-8855490 https://reactome.org/PathwayBrowser/#/R-SSC-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Sus scrofa 133940 R-BTA-176588 https://reactome.org/PathwayBrowser/#/R-BTA-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Bos taurus 133940 R-DME-176588 https://reactome.org/PathwayBrowser/#/R-DME-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Drosophila melanogaster 133940 R-DRE-176588 https://reactome.org/PathwayBrowser/#/R-DRE-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Danio rerio 133940 R-GGA-176588 https://reactome.org/PathwayBrowser/#/R-GGA-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Gallus gallus 133940 R-HSA-176588 https://reactome.org/PathwayBrowser/#/R-HSA-176588 lithocholate + PAPS => lithocholate sulfate + PAP TAS Homo sapiens 133940 R-MMU-176588 https://reactome.org/PathwayBrowser/#/R-MMU-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Mus musculus 133940 R-RNO-176588 https://reactome.org/PathwayBrowser/#/R-RNO-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Rattus norvegicus 133940 R-SSC-176588 https://reactome.org/PathwayBrowser/#/R-SSC-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Sus scrofa 133940 R-XTR-176588 https://reactome.org/PathwayBrowser/#/R-XTR-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Xenopus tropicalis 133969 R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 133969 R-HSA-9681314 https://reactome.org/PathwayBrowser/#/R-HSA-9681314 Replication transcription complex binds SARS-CoV-1 genomic RNA TAS Homo sapiens 133969 R-HSA-9681651 https://reactome.org/PathwayBrowser/#/R-HSA-9681651 nsp8 generates RNA primers TAS Homo sapiens 133969 R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 133969 R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 133969 R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 133969 R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 133969 R-HSA-9682603 https://reactome.org/PathwayBrowser/#/R-HSA-9682603 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 133969 R-HSA-9682695 https://reactome.org/PathwayBrowser/#/R-HSA-9682695 nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template TAS Homo sapiens 133969 R-HSA-9683618 https://reactome.org/PathwayBrowser/#/R-HSA-9683618 mRNA3 is translated to protein 3a TAS Homo sapiens 133969 R-HSA-9683622 https://reactome.org/PathwayBrowser/#/R-HSA-9683622 mRNA5 is translated to protein M TAS Homo sapiens 133969 R-HSA-9683624 https://reactome.org/PathwayBrowser/#/R-HSA-9683624 mRNA2 is translated to Spike TAS Homo sapiens 133969 R-HSA-9683656 https://reactome.org/PathwayBrowser/#/R-HSA-9683656 mRNA4 is translated to protein E TAS Homo sapiens 133969 R-HSA-9683735 https://reactome.org/PathwayBrowser/#/R-HSA-9683735 mRNA9 is translated to Nucleoprotein TAS Homo sapiens 133969 R-HSA-9684030 https://reactome.org/PathwayBrowser/#/R-HSA-9684030 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 133969 R-HSA-9684032 https://reactome.org/PathwayBrowser/#/R-HSA-9684032 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 133969 R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 133969 R-HSA-9684229 https://reactome.org/PathwayBrowser/#/R-HSA-9684229 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 133969 R-HSA-9684234 https://reactome.org/PathwayBrowser/#/R-HSA-9684234 Encapsidation of SARS coronavirus genomic RNA TAS Homo sapiens 133969 R-HSA-9684238 https://reactome.org/PathwayBrowser/#/R-HSA-9684238 E and N are recruited to the M lattice TAS Homo sapiens 133969 R-HSA-9684241 https://reactome.org/PathwayBrowser/#/R-HSA-9684241 Recruitment of Spike trimer to assembling virion TAS Homo sapiens 133969 R-HSA-9684277 https://reactome.org/PathwayBrowser/#/R-HSA-9684277 mRNA1 is translated to pp1ab TAS Homo sapiens 133969 R-HSA-9684301 https://reactome.org/PathwayBrowser/#/R-HSA-9684301 mRNA1 is translated to pp1a TAS Homo sapiens 133969 R-HSA-9685519 https://reactome.org/PathwayBrowser/#/R-HSA-9685519 Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) TAS Homo sapiens 133969 R-HSA-9685531 https://reactome.org/PathwayBrowser/#/R-HSA-9685531 SARS virus buds into ERGIC lumen TAS Homo sapiens 133969 R-HSA-9685597 https://reactome.org/PathwayBrowser/#/R-HSA-9685597 RTC binds SARS-CoV-1 genomic RNA complement (minus strand) TAS Homo sapiens 133969 R-HSA-9685639 https://reactome.org/PathwayBrowser/#/R-HSA-9685639 Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching TAS Homo sapiens 133969 R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-HSA-9686174 https://reactome.org/PathwayBrowser/#/R-HSA-9686174 Accessory proteins are recruited to the maturing virion TAS Homo sapiens 133969 R-HSA-9687384 https://reactome.org/PathwayBrowser/#/R-HSA-9687384 SARS-CoV-1 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 133969 R-HSA-9687388 https://reactome.org/PathwayBrowser/#/R-HSA-9687388 SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 133969 R-HSA-9693589 https://reactome.org/PathwayBrowser/#/R-HSA-9693589 SARS-CoV-1 dsRNA intermediates bind DDX58 TAS Homo sapiens 133969 R-HSA-9693590 https://reactome.org/PathwayBrowser/#/R-HSA-9693590 SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC IEA Homo sapiens 133969 R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 133969 R-HSA-9694274 https://reactome.org/PathwayBrowser/#/R-HSA-9694274 mRNA1 is translated to pp1ab IEA Homo sapiens 133969 R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 133969 R-HSA-9694280 https://reactome.org/PathwayBrowser/#/R-HSA-9694280 mRNA4 is translated to protein E TAS Homo sapiens 133969 R-HSA-9694281 https://reactome.org/PathwayBrowser/#/R-HSA-9694281 Encapsidation of SARS coronavirus genomic RNA IEA Homo sapiens 133969 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 133969 R-HSA-9694334 https://reactome.org/PathwayBrowser/#/R-HSA-9694334 mRNA1 is translated to pp1a IEA Homo sapiens 133969 R-HSA-9694344 https://reactome.org/PathwayBrowser/#/R-HSA-9694344 Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching IEA Homo sapiens 133969 R-HSA-9694370 https://reactome.org/PathwayBrowser/#/R-HSA-9694370 mRNA9a is translated to Nucleoprotein TAS Homo sapiens 133969 R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 133969 R-HSA-9694444 https://reactome.org/PathwayBrowser/#/R-HSA-9694444 E and N are recruited to the M lattice IEA Homo sapiens 133969 R-HSA-9694447 https://reactome.org/PathwayBrowser/#/R-HSA-9694447 mRNA2 is translated to Spike TAS Homo sapiens 133969 R-HSA-9694454 https://reactome.org/PathwayBrowser/#/R-HSA-9694454 Replication transcription complex binds SARS-CoV-2 genomic RNA TAS Homo sapiens 133969 R-HSA-9694455 https://reactome.org/PathwayBrowser/#/R-HSA-9694455 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 133969 R-HSA-9694471 https://reactome.org/PathwayBrowser/#/R-HSA-9694471 Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) TAS Homo sapiens 133969 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-HSA-9694495 https://reactome.org/PathwayBrowser/#/R-HSA-9694495 RTC binds SARS-CoV-2 genomic RNA complement (minus strand) IEA Homo sapiens 133969 R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 133969 R-HSA-9694528 https://reactome.org/PathwayBrowser/#/R-HSA-9694528 Accessory proteins are recruited to the maturing virion IEA Homo sapiens 133969 R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 133969 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 133969 R-HSA-9694553 https://reactome.org/PathwayBrowser/#/R-HSA-9694553 Recruitment of Spike trimer to assembling virion IEA Homo sapiens 133969 R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 133969 R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 133969 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 133969 R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 133969 R-HSA-9694633 https://reactome.org/PathwayBrowser/#/R-HSA-9694633 SARS virus buds into ERGIC lumen IEA Homo sapiens 133969 R-HSA-9694641 https://reactome.org/PathwayBrowser/#/R-HSA-9694641 Viral release IEA Homo sapiens 133969 R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 133969 R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 133969 R-HSA-9694677 https://reactome.org/PathwayBrowser/#/R-HSA-9694677 ZCRB1 binds 5'UTR of SARS-CoV-2 genomic RNA IEA Homo sapiens 133969 R-HSA-9694681 https://reactome.org/PathwayBrowser/#/R-HSA-9694681 mRNA5 is translated to protein M TAS Homo sapiens 133969 R-HSA-9694689 https://reactome.org/PathwayBrowser/#/R-HSA-9694689 Fusion and Release of SARS-CoV-2 Nucleocapsid IEA Homo sapiens 133969 R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 133969 R-HSA-9694723 https://reactome.org/PathwayBrowser/#/R-HSA-9694723 Uncoating of SARS-CoV-2 Genome IEA Homo sapiens 133969 R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 133969 R-HSA-9694794 https://reactome.org/PathwayBrowser/#/R-HSA-9694794 mRNA3 is translated to protein 3a TAS Homo sapiens 133969 R-HSA-9697423 https://reactome.org/PathwayBrowser/#/R-HSA-9697423 Endocytosis of SARS-CoV-2 Virion IEA Homo sapiens 133969 R-HSA-9698988 https://reactome.org/PathwayBrowser/#/R-HSA-9698988 Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid TAS Homo sapiens 133969 R-HSA-9699007 https://reactome.org/PathwayBrowser/#/R-HSA-9699007 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 133969 R-HSA-9705961 https://reactome.org/PathwayBrowser/#/R-HSA-9705961 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 133969 R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 133969 R-HSA-9727292 https://reactome.org/PathwayBrowser/#/R-HSA-9727292 mRNA6 is translated to protein 6 TAS Homo sapiens 133969 R-HSA-9727297 https://reactome.org/PathwayBrowser/#/R-HSA-9727297 mRNA7 is translated to protein 7a TAS Homo sapiens 133969 R-HSA-9727303 https://reactome.org/PathwayBrowser/#/R-HSA-9727303 mRNA9 is translated to protein 9b TAS Homo sapiens 133969 R-HSA-9727305 https://reactome.org/PathwayBrowser/#/R-HSA-9727305 mRNA8 is translated to protein 8 TAS Homo sapiens 133969 R-HSA-9754745 https://reactome.org/PathwayBrowser/#/R-HSA-9754745 IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 133969 R-HSA-9755252 https://reactome.org/PathwayBrowser/#/R-HSA-9755252 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 133969 R-HSA-9755258 https://reactome.org/PathwayBrowser/#/R-HSA-9755258 DDX58 binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 133969 R-HSA-9755368 https://reactome.org/PathwayBrowser/#/R-HSA-9755368 TLR2:TLR1 binds SARS-CoV-2 E pentamer TAS Homo sapiens 133969 R-HSA-9756574 https://reactome.org/PathwayBrowser/#/R-HSA-9756574 SARS-CoV-2 S binds SFTPD 12mer TAS Homo sapiens 133969 R-HSA-9759709 https://reactome.org/PathwayBrowser/#/R-HSA-9759709 CNBP binds SARS-CoV-2 G-rich RNA TAS Homo sapiens 133969 R-HSA-9760510 https://reactome.org/PathwayBrowser/#/R-HSA-9760510 LARP1 binds SARS-CoV-2 RNA TAS Homo sapiens 133969 R-HSA-9769949 https://reactome.org/PathwayBrowser/#/R-HSA-9769949 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage TAS Homo sapiens 133969 R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 133977 R-BTA-176054 https://reactome.org/PathwayBrowser/#/R-BTA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Bos taurus 133977 R-BTA-3301943 https://reactome.org/PathwayBrowser/#/R-BTA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Bos taurus 133977 R-CEL-176054 https://reactome.org/PathwayBrowser/#/R-CEL-176054 GST dimers conjugate GSH with cytosolic substrates IEA Caenorhabditis elegans 133977 R-CEL-3301943 https://reactome.org/PathwayBrowser/#/R-CEL-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Caenorhabditis elegans 133977 R-CFA-176054 https://reactome.org/PathwayBrowser/#/R-CFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Canis familiaris 133977 R-CFA-3301943 https://reactome.org/PathwayBrowser/#/R-CFA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Canis familiaris 133977 R-DDI-176054 https://reactome.org/PathwayBrowser/#/R-DDI-176054 GST dimers conjugate GSH with cytosolic substrates IEA Dictyostelium discoideum 133977 R-DME-176054 https://reactome.org/PathwayBrowser/#/R-DME-176054 GST dimers conjugate GSH with cytosolic substrates IEA Drosophila melanogaster 133977 R-DRE-176054 https://reactome.org/PathwayBrowser/#/R-DRE-176054 GST dimers conjugate GSH with cytosolic substrates IEA Danio rerio 133977 R-DRE-3301943 https://reactome.org/PathwayBrowser/#/R-DRE-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Danio rerio 133977 R-GGA-176054 https://reactome.org/PathwayBrowser/#/R-GGA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Gallus gallus 133977 R-GGA-3301943 https://reactome.org/PathwayBrowser/#/R-GGA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Gallus gallus 133977 R-HSA-176054 https://reactome.org/PathwayBrowser/#/R-HSA-176054 GST dimers conjugate GSH with cytosolic substrates TAS Homo sapiens 133977 R-HSA-3301943 https://reactome.org/PathwayBrowser/#/R-HSA-3301943 GSTK1 dimer transfers GS from GSH to CDNB TAS Homo sapiens 133977 R-MMU-176054 https://reactome.org/PathwayBrowser/#/R-MMU-176054 GST dimers conjugate GSH with cytosolic substrates IEA Mus musculus 133977 R-MMU-3301943 https://reactome.org/PathwayBrowser/#/R-MMU-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Mus musculus 133977 R-PFA-176054 https://reactome.org/PathwayBrowser/#/R-PFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Plasmodium falciparum 133977 R-RNO-176054 https://reactome.org/PathwayBrowser/#/R-RNO-176054 GST dimers conjugate GSH with cytosolic substrates IEA Rattus norvegicus 133977 R-RNO-3301943 https://reactome.org/PathwayBrowser/#/R-RNO-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Rattus norvegicus 133977 R-SSC-176054 https://reactome.org/PathwayBrowser/#/R-SSC-176054 GST dimers conjugate GSH with cytosolic substrates IEA Sus scrofa 133977 R-SSC-3301943 https://reactome.org/PathwayBrowser/#/R-SSC-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Sus scrofa 133977 R-XTR-176054 https://reactome.org/PathwayBrowser/#/R-XTR-176054 GST dimers conjugate GSH with cytosolic substrates IEA Xenopus tropicalis 134020 R-BTA-9673053 https://reactome.org/PathwayBrowser/#/R-BTA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Bos taurus 134020 R-BTA-9673054 https://reactome.org/PathwayBrowser/#/R-BTA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Bos taurus 134020 R-CFA-9673053 https://reactome.org/PathwayBrowser/#/R-CFA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Canis familiaris 134020 R-CFA-9673054 https://reactome.org/PathwayBrowser/#/R-CFA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Canis familiaris 134020 R-DDI-9673053 https://reactome.org/PathwayBrowser/#/R-DDI-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Dictyostelium discoideum 134020 R-DDI-9673054 https://reactome.org/PathwayBrowser/#/R-DDI-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Dictyostelium discoideum 134020 R-DRE-9673053 https://reactome.org/PathwayBrowser/#/R-DRE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Danio rerio 134020 R-DRE-9673054 https://reactome.org/PathwayBrowser/#/R-DRE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Danio rerio 134020 R-GGA-9673053 https://reactome.org/PathwayBrowser/#/R-GGA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Gallus gallus 134020 R-GGA-9673054 https://reactome.org/PathwayBrowser/#/R-GGA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Gallus gallus 134020 R-HSA-9673053 https://reactome.org/PathwayBrowser/#/R-HSA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe TAS Homo sapiens 134020 R-HSA-9673054 https://reactome.org/PathwayBrowser/#/R-HSA-9673054 PM20D1 hydrolyzes oleoyl-phe TAS Homo sapiens 134020 R-MMU-9673053 https://reactome.org/PathwayBrowser/#/R-MMU-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Mus musculus 134020 R-MMU-9673054 https://reactome.org/PathwayBrowser/#/R-MMU-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Mus musculus 134020 R-RNO-9673053 https://reactome.org/PathwayBrowser/#/R-RNO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Rattus norvegicus 134020 R-RNO-9673054 https://reactome.org/PathwayBrowser/#/R-RNO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Rattus norvegicus 134020 R-SCE-9673053 https://reactome.org/PathwayBrowser/#/R-SCE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Saccharomyces cerevisiae 134020 R-SCE-9673054 https://reactome.org/PathwayBrowser/#/R-SCE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Saccharomyces cerevisiae 134020 R-SPO-9673053 https://reactome.org/PathwayBrowser/#/R-SPO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Schizosaccharomyces pombe 134020 R-SPO-9673054 https://reactome.org/PathwayBrowser/#/R-SPO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Schizosaccharomyces pombe 134020 R-SSC-9673053 https://reactome.org/PathwayBrowser/#/R-SSC-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Sus scrofa 134020 R-SSC-9673054 https://reactome.org/PathwayBrowser/#/R-SSC-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Sus scrofa 134020 R-XTR-9673053 https://reactome.org/PathwayBrowser/#/R-XTR-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Xenopus tropicalis 134020 R-XTR-9673054 https://reactome.org/PathwayBrowser/#/R-XTR-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Xenopus tropicalis 134117 R-BTA-8952137 https://reactome.org/PathwayBrowser/#/R-BTA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Bos taurus 134117 R-CEL-8952137 https://reactome.org/PathwayBrowser/#/R-CEL-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Caenorhabditis elegans 134117 R-CFA-8952137 https://reactome.org/PathwayBrowser/#/R-CFA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Canis familiaris 134117 R-DDI-8952137 https://reactome.org/PathwayBrowser/#/R-DDI-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Dictyostelium discoideum 134117 R-DME-8952137 https://reactome.org/PathwayBrowser/#/R-DME-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Drosophila melanogaster 134117 R-DRE-8952137 https://reactome.org/PathwayBrowser/#/R-DRE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Danio rerio 134117 R-GGA-8952137 https://reactome.org/PathwayBrowser/#/R-GGA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Gallus gallus 134117 R-HSA-8952137 https://reactome.org/PathwayBrowser/#/R-HSA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate TAS Homo sapiens 134117 R-MMU-8952137 https://reactome.org/PathwayBrowser/#/R-MMU-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Mus musculus 134117 R-RNO-8952137 https://reactome.org/PathwayBrowser/#/R-RNO-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Rattus norvegicus 134117 R-SCE-8952137 https://reactome.org/PathwayBrowser/#/R-SCE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Saccharomyces cerevisiae 134117 R-SSC-8952137 https://reactome.org/PathwayBrowser/#/R-SSC-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Sus scrofa 134117 R-XTR-8952137 https://reactome.org/PathwayBrowser/#/R-XTR-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Xenopus tropicalis 134401 R-MTU-868657 https://reactome.org/PathwayBrowser/#/R-MTU-868657 Glucanotrehalose is hydrolyzed to 1,4-alpha-glucan and trehalose TAS Mycobacterium tuberculosis 134401 R-MTU-868658 https://reactome.org/PathwayBrowser/#/R-MTU-868658 1,4-alpha-glucan is converted to glucanotrehalose TAS Mycobacterium tuberculosis 134407 R-BTA-9028255 https://reactome.org/PathwayBrowser/#/R-BTA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Bos taurus 134407 R-CFA-9028255 https://reactome.org/PathwayBrowser/#/R-CFA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Canis familiaris 134407 R-DRE-9028255 https://reactome.org/PathwayBrowser/#/R-DRE-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Danio rerio 134407 R-GGA-9028255 https://reactome.org/PathwayBrowser/#/R-GGA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Gallus gallus 134407 R-HSA-9028255 https://reactome.org/PathwayBrowser/#/R-HSA-9028255 PTGS2 dimer oxidises EPA to PGH3 TAS Homo sapiens 134407 R-HSA-9028273 https://reactome.org/PathwayBrowser/#/R-HSA-9028273 PGH3 spontaneously dehydrates to PGJ3 TAS Homo sapiens 134407 R-MMU-9028255 https://reactome.org/PathwayBrowser/#/R-MMU-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Mus musculus 134407 R-RNO-9028255 https://reactome.org/PathwayBrowser/#/R-RNO-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Rattus norvegicus 134407 R-SSC-9028255 https://reactome.org/PathwayBrowser/#/R-SSC-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Sus scrofa 134407 R-XTR-9028255 https://reactome.org/PathwayBrowser/#/R-XTR-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Xenopus tropicalis 135010 R-BTA-9629679 https://reactome.org/PathwayBrowser/#/R-BTA-9629679 PDE3A inhibitors bind PDE3A IEA Bos taurus 135010 R-CEL-9629679 https://reactome.org/PathwayBrowser/#/R-CEL-9629679 PDE3A inhibitors bind PDE3A IEA Caenorhabditis elegans 135010 R-CFA-9629679 https://reactome.org/PathwayBrowser/#/R-CFA-9629679 PDE3A inhibitors bind PDE3A IEA Canis familiaris 135010 R-DDI-9629679 https://reactome.org/PathwayBrowser/#/R-DDI-9629679 PDE3A inhibitors bind PDE3A IEA Dictyostelium discoideum 135010 R-GGA-9629679 https://reactome.org/PathwayBrowser/#/R-GGA-9629679 PDE3A inhibitors bind PDE3A IEA Gallus gallus 135010 R-HSA-9629679 https://reactome.org/PathwayBrowser/#/R-HSA-9629679 PDE3A inhibitors bind PDE3A TAS Homo sapiens 135010 R-MMU-9629679 https://reactome.org/PathwayBrowser/#/R-MMU-9629679 PDE3A inhibitors bind PDE3A IEA Mus musculus 135010 R-PFA-9629679 https://reactome.org/PathwayBrowser/#/R-PFA-9629679 PDE3A inhibitors bind PDE3A IEA Plasmodium falciparum 135010 R-RNO-9629679 https://reactome.org/PathwayBrowser/#/R-RNO-9629679 PDE3A inhibitors bind PDE3A IEA Rattus norvegicus 135010 R-SSC-9629679 https://reactome.org/PathwayBrowser/#/R-SSC-9629679 PDE3A inhibitors bind PDE3A IEA Sus scrofa 135123 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 135123 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 135123 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 135123 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 135123 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 135123 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 135123 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 135123 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 135123 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 135123 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 135123 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 135123 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 135123 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 135123 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 135123 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 135123 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 135123 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 135123 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 135123 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 135123 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 135123 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 135123 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 135123 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 135123 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 135123 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 135123 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 135123 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 135123 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 135123 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 135123 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 135123 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 135123 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 135123 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 135123 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 135123 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 135123 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 135123 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 135349 R-BTA-9650858 https://reactome.org/PathwayBrowser/#/R-BTA-9650858 Meglitinides bind ABCC8 IEA Bos taurus 135349 R-CFA-9650858 https://reactome.org/PathwayBrowser/#/R-CFA-9650858 Meglitinides bind ABCC8 IEA Canis familiaris 135349 R-DME-9650858 https://reactome.org/PathwayBrowser/#/R-DME-9650858 Meglitinides bind ABCC8 IEA Drosophila melanogaster 135349 R-GGA-9650858 https://reactome.org/PathwayBrowser/#/R-GGA-9650858 Meglitinides bind ABCC8 IEA Gallus gallus 135349 R-HSA-9650858 https://reactome.org/PathwayBrowser/#/R-HSA-9650858 Meglitinides bind ABCC8 TAS Homo sapiens 135349 R-MMU-9650858 https://reactome.org/PathwayBrowser/#/R-MMU-9650858 Meglitinides bind ABCC8 IEA Mus musculus 135349 R-RNO-9650858 https://reactome.org/PathwayBrowser/#/R-RNO-9650858 Meglitinides bind ABCC8 IEA Rattus norvegicus 135349 R-SSC-9650858 https://reactome.org/PathwayBrowser/#/R-SSC-9650858 Meglitinides bind ABCC8 IEA Sus scrofa 135349 R-XTR-9650858 https://reactome.org/PathwayBrowser/#/R-XTR-9650858 Meglitinides bind ABCC8 IEA Xenopus tropicalis 135359 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 135359 R-BTA-9611721 https://reactome.org/PathwayBrowser/#/R-BTA-9611721 β1-agonists bind ADRB1 IEA Bos taurus 135359 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 135359 R-DME-9611721 https://reactome.org/PathwayBrowser/#/R-DME-9611721 β1-agonists bind ADRB1 IEA Drosophila melanogaster 135359 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 135359 R-DRE-9611721 https://reactome.org/PathwayBrowser/#/R-DRE-9611721 β1-agonists bind ADRB1 IEA Danio rerio 135359 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 135359 R-GGA-9611721 https://reactome.org/PathwayBrowser/#/R-GGA-9611721 β1-agonists bind ADRB1 IEA Gallus gallus 135359 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 135359 R-HSA-9611721 https://reactome.org/PathwayBrowser/#/R-HSA-9611721 β1-agonists bind ADRB1 TAS Homo sapiens 135359 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 135359 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 135359 R-MMU-9611721 https://reactome.org/PathwayBrowser/#/R-MMU-9611721 β1-agonists bind ADRB1 IEA Mus musculus 135359 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 135359 R-RNO-9611721 https://reactome.org/PathwayBrowser/#/R-RNO-9611721 β1-agonists bind ADRB1 IEA Rattus norvegicus 135359 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 135359 R-SSC-9611721 https://reactome.org/PathwayBrowser/#/R-SSC-9611721 β1-agonists bind ADRB1 IEA Sus scrofa 135359 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 135359 R-XTR-9611721 https://reactome.org/PathwayBrowser/#/R-XTR-9611721 β1-agonists bind ADRB1 IEA Xenopus tropicalis 135361 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 135361 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 135361 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 135361 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 135361 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 135361 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 135361 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 135361 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 135361 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 135361 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 135361 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 135377 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 135377 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 135377 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 135377 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 135377 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 135377 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 135377 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 135377 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 135377 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 135377 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 135377 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 135377 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 135377 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 135377 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 135377 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 135377 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 135377 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 135377 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 135377 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 135377 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 135377 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 135377 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 135377 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 135377 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 135377 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 135377 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 135377 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 135377 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 135377 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 135377 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 135377 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 135377 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 135377 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 135377 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 135377 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 135377 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 135377 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 135566 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 135566 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 135566 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 135566 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 135566 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 135566 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 135566 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 135566 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 135566 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 135566 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 135566 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 135566 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 135566 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 135566 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 135566 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 135566 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 135566 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 135566 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 135566 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 135566 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 135566 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 135566 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 135654 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 135654 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 135654 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 135654 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 135654 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 135654 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 135654 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 135654 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 135654 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 135654 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 135654 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 135654 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 135720 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 135720 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 135720 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 135720 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 135720 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 135720 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 135720 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 135720 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 135720 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 135720 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 135720 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 135720 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 135720 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 135720 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 135720 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 135720 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 135720 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 135720 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 135720 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 135720 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 135720 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 135720 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 135738 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 135738 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 135738 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 135738 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 135738 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 135738 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 135738 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 135738 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 135738 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 135738 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 135741 R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 135741 R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 135741 R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 135741 R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 135741 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 135741 R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 135741 R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 135741 R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 135741 R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 135741 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 135741 R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 135756 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 135756 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 135756 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 135756 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 135756 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 135756 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 135756 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 135756 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 135756 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 135756 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 135756 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 135756 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 136113 R-BTA-9020273 https://reactome.org/PathwayBrowser/#/R-BTA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Bos taurus 136113 R-BTA-9020275 https://reactome.org/PathwayBrowser/#/R-BTA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Bos taurus 136113 R-BTA-9024872 https://reactome.org/PathwayBrowser/#/R-BTA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Bos taurus 136113 R-BTA-9024881 https://reactome.org/PathwayBrowser/#/R-BTA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Bos taurus 136113 R-CEL-9020273 https://reactome.org/PathwayBrowser/#/R-CEL-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Caenorhabditis elegans 136113 R-CFA-9020273 https://reactome.org/PathwayBrowser/#/R-CFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Canis familiaris 136113 R-CFA-9020275 https://reactome.org/PathwayBrowser/#/R-CFA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Canis familiaris 136113 R-CFA-9024872 https://reactome.org/PathwayBrowser/#/R-CFA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Canis familiaris 136113 R-CFA-9024881 https://reactome.org/PathwayBrowser/#/R-CFA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Canis familiaris 136113 R-DDI-9020275 https://reactome.org/PathwayBrowser/#/R-DDI-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Dictyostelium discoideum 136113 R-DDI-9024872 https://reactome.org/PathwayBrowser/#/R-DDI-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Dictyostelium discoideum 136113 R-DDI-9024881 https://reactome.org/PathwayBrowser/#/R-DDI-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Dictyostelium discoideum 136113 R-DRE-9020275 https://reactome.org/PathwayBrowser/#/R-DRE-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Danio rerio 136113 R-DRE-9024872 https://reactome.org/PathwayBrowser/#/R-DRE-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Danio rerio 136113 R-DRE-9024881 https://reactome.org/PathwayBrowser/#/R-DRE-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Danio rerio 136113 R-GGA-9020273 https://reactome.org/PathwayBrowser/#/R-GGA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Gallus gallus 136113 R-HSA-9020273 https://reactome.org/PathwayBrowser/#/R-HSA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA TAS Homo sapiens 136113 R-HSA-9020275 https://reactome.org/PathwayBrowser/#/R-HSA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA TAS Homo sapiens 136113 R-HSA-9024872 https://reactome.org/PathwayBrowser/#/R-HSA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX TAS Homo sapiens 136113 R-HSA-9024881 https://reactome.org/PathwayBrowser/#/R-HSA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA TAS Homo sapiens 136113 R-HSA-9026918 https://reactome.org/PathwayBrowser/#/R-HSA-9026918 Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA TAS Homo sapiens 136113 R-MMU-9020273 https://reactome.org/PathwayBrowser/#/R-MMU-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Mus musculus 136113 R-MMU-9020275 https://reactome.org/PathwayBrowser/#/R-MMU-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Mus musculus 136113 R-MMU-9024872 https://reactome.org/PathwayBrowser/#/R-MMU-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Mus musculus 136113 R-MMU-9024881 https://reactome.org/PathwayBrowser/#/R-MMU-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Mus musculus 136113 R-PFA-9020273 https://reactome.org/PathwayBrowser/#/R-PFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Plasmodium falciparum 136113 R-RNO-9020273 https://reactome.org/PathwayBrowser/#/R-RNO-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Rattus norvegicus 136113 R-RNO-9020275 https://reactome.org/PathwayBrowser/#/R-RNO-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Rattus norvegicus 136113 R-RNO-9024872 https://reactome.org/PathwayBrowser/#/R-RNO-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Rattus norvegicus 136113 R-RNO-9024881 https://reactome.org/PathwayBrowser/#/R-RNO-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Rattus norvegicus 136113 R-SSC-9020273 https://reactome.org/PathwayBrowser/#/R-SSC-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Sus scrofa 136113 R-SSC-9020275 https://reactome.org/PathwayBrowser/#/R-SSC-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Sus scrofa 136113 R-SSC-9024872 https://reactome.org/PathwayBrowser/#/R-SSC-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Sus scrofa 136113 R-SSC-9024881 https://reactome.org/PathwayBrowser/#/R-SSC-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Sus scrofa 136352 R-BTA-9027607 https://reactome.org/PathwayBrowser/#/R-BTA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Bos taurus 136352 R-CFA-9027607 https://reactome.org/PathwayBrowser/#/R-CFA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Canis familiaris 136352 R-DRE-9027607 https://reactome.org/PathwayBrowser/#/R-DRE-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Danio rerio 136352 R-GGA-9027607 https://reactome.org/PathwayBrowser/#/R-GGA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Gallus gallus 136352 R-HSA-9027600 https://reactome.org/PathwayBrowser/#/R-HSA-9027600 Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3 TAS Homo sapiens 136352 R-HSA-9027607 https://reactome.org/PathwayBrowser/#/R-HSA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 TAS Homo sapiens 136352 R-MMU-9027607 https://reactome.org/PathwayBrowser/#/R-MMU-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Mus musculus 136352 R-RNO-9027607 https://reactome.org/PathwayBrowser/#/R-RNO-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Rattus norvegicus 136352 R-SSC-9027607 https://reactome.org/PathwayBrowser/#/R-SSC-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Sus scrofa 136352 R-XTR-9027607 https://reactome.org/PathwayBrowser/#/R-XTR-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Xenopus tropicalis 136579 R-BTA-176609 https://reactome.org/PathwayBrowser/#/R-BTA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Bos taurus 136579 R-CFA-176609 https://reactome.org/PathwayBrowser/#/R-CFA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Canis familiaris 136579 R-DME-176609 https://reactome.org/PathwayBrowser/#/R-DME-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Drosophila melanogaster 136579 R-DRE-176609 https://reactome.org/PathwayBrowser/#/R-DRE-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Danio rerio 136579 R-GGA-176609 https://reactome.org/PathwayBrowser/#/R-GGA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Gallus gallus 136579 R-HSA-176609 https://reactome.org/PathwayBrowser/#/R-HSA-176609 cholesterol + PAPS => cholesterol sulfate + PAP TAS Homo sapiens 136579 R-MMU-176609 https://reactome.org/PathwayBrowser/#/R-MMU-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Mus musculus 136579 R-RNO-176609 https://reactome.org/PathwayBrowser/#/R-RNO-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Rattus norvegicus 136579 R-SSC-176609 https://reactome.org/PathwayBrowser/#/R-SSC-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Sus scrofa 136579 R-XTR-176609 https://reactome.org/PathwayBrowser/#/R-XTR-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Xenopus tropicalis 136721 R-HSA-9670149 https://reactome.org/PathwayBrowser/#/R-HSA-9670149 TERRA transcription TAS Homo sapiens 136806 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 136806 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 136806 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 136806 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 136806 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 136806 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 136806 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 136806 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 136806 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 136806 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 137011 R-BTA-9026405 https://reactome.org/PathwayBrowser/#/R-BTA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Bos taurus 137011 R-CFA-9026405 https://reactome.org/PathwayBrowser/#/R-CFA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Canis familiaris 137011 R-DDI-9026405 https://reactome.org/PathwayBrowser/#/R-DDI-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Dictyostelium discoideum 137011 R-DRE-9026405 https://reactome.org/PathwayBrowser/#/R-DRE-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Danio rerio 137011 R-GGA-9026405 https://reactome.org/PathwayBrowser/#/R-GGA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Gallus gallus 137011 R-HSA-9026405 https://reactome.org/PathwayBrowser/#/R-HSA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 TAS Homo sapiens 137011 R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 137011 R-MMU-9026405 https://reactome.org/PathwayBrowser/#/R-MMU-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Mus musculus 137011 R-RNO-9026405 https://reactome.org/PathwayBrowser/#/R-RNO-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Rattus norvegicus 137011 R-SSC-9026405 https://reactome.org/PathwayBrowser/#/R-SSC-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Sus scrofa 137011 R-XTR-9026405 https://reactome.org/PathwayBrowser/#/R-XTR-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Xenopus tropicalis 137018 R-BTA-9026405 https://reactome.org/PathwayBrowser/#/R-BTA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Bos taurus 137018 R-CFA-9026405 https://reactome.org/PathwayBrowser/#/R-CFA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Canis familiaris 137018 R-DDI-9026405 https://reactome.org/PathwayBrowser/#/R-DDI-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Dictyostelium discoideum 137018 R-DRE-9026405 https://reactome.org/PathwayBrowser/#/R-DRE-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Danio rerio 137018 R-GGA-9026405 https://reactome.org/PathwayBrowser/#/R-GGA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Gallus gallus 137018 R-HSA-9026405 https://reactome.org/PathwayBrowser/#/R-HSA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 TAS Homo sapiens 137018 R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 137018 R-MMU-9026405 https://reactome.org/PathwayBrowser/#/R-MMU-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Mus musculus 137018 R-RNO-9026405 https://reactome.org/PathwayBrowser/#/R-RNO-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Rattus norvegicus 137018 R-SSC-9026405 https://reactome.org/PathwayBrowser/#/R-SSC-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Sus scrofa 137018 R-XTR-9026405 https://reactome.org/PathwayBrowser/#/R-XTR-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Xenopus tropicalis 137019 R-BTA-9026405 https://reactome.org/PathwayBrowser/#/R-BTA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Bos taurus 137019 R-CFA-9026405 https://reactome.org/PathwayBrowser/#/R-CFA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Canis familiaris 137019 R-DDI-9026405 https://reactome.org/PathwayBrowser/#/R-DDI-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Dictyostelium discoideum 137019 R-DRE-9026405 https://reactome.org/PathwayBrowser/#/R-DRE-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Danio rerio 137019 R-GGA-9026405 https://reactome.org/PathwayBrowser/#/R-GGA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Gallus gallus 137019 R-HSA-9026405 https://reactome.org/PathwayBrowser/#/R-HSA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 TAS Homo sapiens 137019 R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 137019 R-MMU-9026405 https://reactome.org/PathwayBrowser/#/R-MMU-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Mus musculus 137019 R-RNO-9026405 https://reactome.org/PathwayBrowser/#/R-RNO-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Rattus norvegicus 137019 R-SSC-9026405 https://reactome.org/PathwayBrowser/#/R-SSC-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Sus scrofa 137019 R-XTR-9026405 https://reactome.org/PathwayBrowser/#/R-XTR-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Xenopus tropicalis 137020 R-BTA-9026405 https://reactome.org/PathwayBrowser/#/R-BTA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Bos taurus 137020 R-CFA-9026405 https://reactome.org/PathwayBrowser/#/R-CFA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Canis familiaris 137020 R-DDI-9026405 https://reactome.org/PathwayBrowser/#/R-DDI-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Dictyostelium discoideum 137020 R-DRE-9026405 https://reactome.org/PathwayBrowser/#/R-DRE-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Danio rerio 137020 R-GGA-9026405 https://reactome.org/PathwayBrowser/#/R-GGA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Gallus gallus 137020 R-HSA-9026405 https://reactome.org/PathwayBrowser/#/R-HSA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 TAS Homo sapiens 137020 R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 137020 R-MMU-9026405 https://reactome.org/PathwayBrowser/#/R-MMU-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Mus musculus 137020 R-RNO-9026405 https://reactome.org/PathwayBrowser/#/R-RNO-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Rattus norvegicus 137020 R-SSC-9026405 https://reactome.org/PathwayBrowser/#/R-SSC-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Sus scrofa 137020 R-XTR-9026405 https://reactome.org/PathwayBrowser/#/R-XTR-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Xenopus tropicalis 137034 R-HSA-9018867 https://reactome.org/PathwayBrowser/#/R-HSA-9018867 5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2 TAS Homo sapiens 137034 R-HSA-9023980 https://reactome.org/PathwayBrowser/#/R-HSA-9023980 18(S)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 137038 R-BTA-8862700 https://reactome.org/PathwayBrowser/#/R-BTA-8862700 CMKLR1 binds Resolvin E1 IEA Bos taurus 137038 R-BTA-9018862 https://reactome.org/PathwayBrowser/#/R-BTA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Bos taurus 137038 R-BTA-9023968 https://reactome.org/PathwayBrowser/#/R-BTA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Bos taurus 137038 R-CEL-9018862 https://reactome.org/PathwayBrowser/#/R-CEL-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Caenorhabditis elegans 137038 R-CFA-8862700 https://reactome.org/PathwayBrowser/#/R-CFA-8862700 CMKLR1 binds Resolvin E1 IEA Canis familiaris 137038 R-CFA-9018862 https://reactome.org/PathwayBrowser/#/R-CFA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Canis familiaris 137038 R-CFA-9023968 https://reactome.org/PathwayBrowser/#/R-CFA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Canis familiaris 137038 R-DDI-9018862 https://reactome.org/PathwayBrowser/#/R-DDI-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Dictyostelium discoideum 137038 R-DME-9018862 https://reactome.org/PathwayBrowser/#/R-DME-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Drosophila melanogaster 137038 R-DME-9023968 https://reactome.org/PathwayBrowser/#/R-DME-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Drosophila melanogaster 137038 R-DRE-9018862 https://reactome.org/PathwayBrowser/#/R-DRE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Danio rerio 137038 R-DRE-9023968 https://reactome.org/PathwayBrowser/#/R-DRE-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Danio rerio 137038 R-GGA-8862700 https://reactome.org/PathwayBrowser/#/R-GGA-8862700 CMKLR1 binds Resolvin E1 IEA Gallus gallus 137038 R-GGA-9018862 https://reactome.org/PathwayBrowser/#/R-GGA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Gallus gallus 137038 R-GGA-9023968 https://reactome.org/PathwayBrowser/#/R-GGA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Gallus gallus 137038 R-HSA-8862700 https://reactome.org/PathwayBrowser/#/R-HSA-8862700 CMKLR1 binds Resolvin E1 TAS Homo sapiens 137038 R-HSA-9018862 https://reactome.org/PathwayBrowser/#/R-HSA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 TAS Homo sapiens 137038 R-HSA-9023968 https://reactome.org/PathwayBrowser/#/R-HSA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 TAS Homo sapiens 137038 R-HSA-9023980 https://reactome.org/PathwayBrowser/#/R-HSA-9023980 18(S)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 137038 R-MMU-8862700 https://reactome.org/PathwayBrowser/#/R-MMU-8862700 CMKLR1 binds Resolvin E1 IEA Mus musculus 137038 R-MMU-9018862 https://reactome.org/PathwayBrowser/#/R-MMU-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Mus musculus 137038 R-MMU-9023968 https://reactome.org/PathwayBrowser/#/R-MMU-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Mus musculus 137038 R-RNO-8862700 https://reactome.org/PathwayBrowser/#/R-RNO-8862700 CMKLR1 binds Resolvin E1 IEA Rattus norvegicus 137038 R-RNO-9018862 https://reactome.org/PathwayBrowser/#/R-RNO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Rattus norvegicus 137038 R-RNO-9023968 https://reactome.org/PathwayBrowser/#/R-RNO-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Rattus norvegicus 137038 R-SCE-9018862 https://reactome.org/PathwayBrowser/#/R-SCE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Saccharomyces cerevisiae 137038 R-SPO-9018862 https://reactome.org/PathwayBrowser/#/R-SPO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Schizosaccharomyces pombe 137038 R-SSC-8862700 https://reactome.org/PathwayBrowser/#/R-SSC-8862700 CMKLR1 binds Resolvin E1 IEA Sus scrofa 137038 R-SSC-9018862 https://reactome.org/PathwayBrowser/#/R-SSC-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Sus scrofa 137038 R-SSC-9023968 https://reactome.org/PathwayBrowser/#/R-SSC-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Sus scrofa 137038 R-XTR-8862700 https://reactome.org/PathwayBrowser/#/R-XTR-8862700 CMKLR1 binds Resolvin E1 IEA Xenopus tropicalis 137038 R-XTR-9018862 https://reactome.org/PathwayBrowser/#/R-XTR-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Xenopus tropicalis 137038 R-XTR-9023968 https://reactome.org/PathwayBrowser/#/R-XTR-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Xenopus tropicalis 13705 R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 13705 R-BTA-5694494 https://reactome.org/PathwayBrowser/#/R-BTA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Bos taurus 13705 R-BTA-5696457 https://reactome.org/PathwayBrowser/#/R-BTA-5696457 BDH2 dehydrogenates 3HBA IEA Bos taurus 13705 R-BTA-6788597 https://reactome.org/PathwayBrowser/#/R-BTA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Bos taurus 13705 R-BTA-71181 https://reactome.org/PathwayBrowser/#/R-BTA-71181 FAH cleaves 4FAA IEA Bos taurus 13705 R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 13705 R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 13705 R-CEL-5694494 https://reactome.org/PathwayBrowser/#/R-CEL-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Caenorhabditis elegans 13705 R-CEL-6788597 https://reactome.org/PathwayBrowser/#/R-CEL-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Caenorhabditis elegans 13705 R-CEL-71181 https://reactome.org/PathwayBrowser/#/R-CEL-71181 FAH cleaves 4FAA IEA Caenorhabditis elegans 13705 R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 13705 R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 13705 R-CFA-5696457 https://reactome.org/PathwayBrowser/#/R-CFA-5696457 BDH2 dehydrogenates 3HBA IEA Canis familiaris 13705 R-CFA-6788597 https://reactome.org/PathwayBrowser/#/R-CFA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Canis familiaris 13705 R-CFA-71181 https://reactome.org/PathwayBrowser/#/R-CFA-71181 FAH cleaves 4FAA IEA Canis familiaris 13705 R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 13705 R-DDI-6788597 https://reactome.org/PathwayBrowser/#/R-DDI-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Dictyostelium discoideum 13705 R-DDI-71181 https://reactome.org/PathwayBrowser/#/R-DDI-71181 FAH cleaves 4FAA IEA Dictyostelium discoideum 13705 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 13705 R-DME-6788597 https://reactome.org/PathwayBrowser/#/R-DME-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Drosophila melanogaster 13705 R-DME-71181 https://reactome.org/PathwayBrowser/#/R-DME-71181 FAH cleaves 4FAA IEA Drosophila melanogaster 13705 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 13705 R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 13705 R-DRE-5694494 https://reactome.org/PathwayBrowser/#/R-DRE-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Danio rerio 13705 R-DRE-5696457 https://reactome.org/PathwayBrowser/#/R-DRE-5696457 BDH2 dehydrogenates 3HBA IEA Danio rerio 13705 R-DRE-6788597 https://reactome.org/PathwayBrowser/#/R-DRE-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Danio rerio 13705 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 13705 R-GGA-5694494 https://reactome.org/PathwayBrowser/#/R-GGA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Gallus gallus 13705 R-GGA-5696457 https://reactome.org/PathwayBrowser/#/R-GGA-5696457 BDH2 dehydrogenates 3HBA IEA Gallus gallus 13705 R-GGA-6788597 https://reactome.org/PathwayBrowser/#/R-GGA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Gallus gallus 13705 R-GGA-71181 https://reactome.org/PathwayBrowser/#/R-GGA-71181 FAH cleaves 4FAA IEA Gallus gallus 13705 R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 13705 R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13705 R-HSA-5694494 https://reactome.org/PathwayBrowser/#/R-HSA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA TAS Homo sapiens 13705 R-HSA-5696457 https://reactome.org/PathwayBrowser/#/R-HSA-5696457 BDH2 dehydrogenates 3HBA TAS Homo sapiens 13705 R-HSA-6788597 https://reactome.org/PathwayBrowser/#/R-HSA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA TAS Homo sapiens 13705 R-HSA-71181 https://reactome.org/PathwayBrowser/#/R-HSA-71181 FAH cleaves 4FAA TAS Homo sapiens 13705 R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13705 R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 13705 R-MMU-5694494 https://reactome.org/PathwayBrowser/#/R-MMU-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Mus musculus 13705 R-MMU-5696457 https://reactome.org/PathwayBrowser/#/R-MMU-5696457 BDH2 dehydrogenates 3HBA IEA Mus musculus 13705 R-MMU-6788597 https://reactome.org/PathwayBrowser/#/R-MMU-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Mus musculus 13705 R-MMU-71181 https://reactome.org/PathwayBrowser/#/R-MMU-71181 FAH cleaves 4FAA IEA Mus musculus 13705 R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 13705 R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 13705 R-RNO-5694494 https://reactome.org/PathwayBrowser/#/R-RNO-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Rattus norvegicus 13705 R-RNO-5696457 https://reactome.org/PathwayBrowser/#/R-RNO-5696457 BDH2 dehydrogenates 3HBA IEA Rattus norvegicus 13705 R-RNO-6788597 https://reactome.org/PathwayBrowser/#/R-RNO-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Rattus norvegicus 13705 R-RNO-71181 https://reactome.org/PathwayBrowser/#/R-RNO-71181 FAH cleaves 4FAA IEA Rattus norvegicus 13705 R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 13705 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 13705 R-SSC-5694494 https://reactome.org/PathwayBrowser/#/R-SSC-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Sus scrofa 13705 R-SSC-5696457 https://reactome.org/PathwayBrowser/#/R-SSC-5696457 BDH2 dehydrogenates 3HBA IEA Sus scrofa 13705 R-SSC-6788597 https://reactome.org/PathwayBrowser/#/R-SSC-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Sus scrofa 13705 R-SSC-71181 https://reactome.org/PathwayBrowser/#/R-SSC-71181 FAH cleaves 4FAA IEA Sus scrofa 13705 R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 13705 R-XTR-5694494 https://reactome.org/PathwayBrowser/#/R-XTR-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Xenopus tropicalis 13705 R-XTR-6788597 https://reactome.org/PathwayBrowser/#/R-XTR-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Xenopus tropicalis 13705 R-XTR-71181 https://reactome.org/PathwayBrowser/#/R-XTR-71181 FAH cleaves 4FAA IEA Xenopus tropicalis 13705 R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 13719 R-BTA-2314678 https://reactome.org/PathwayBrowser/#/R-BTA-2314678 ASA- acetylates PTGS1 IEA Bos taurus 13719 R-BTA-2314686 https://reactome.org/PathwayBrowser/#/R-BTA-2314686 ASA- acetylates PTGS2 IEA Bos taurus 13719 R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 13719 R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 13719 R-BTA-9749583 https://reactome.org/PathwayBrowser/#/R-BTA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Bos taurus 13719 R-BTA-9749590 https://reactome.org/PathwayBrowser/#/R-BTA-9749590 ASA- acetylates ALB IEA Bos taurus 13719 R-BTA-9749607 https://reactome.org/PathwayBrowser/#/R-BTA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Bos taurus 13719 R-BTA-9749609 https://reactome.org/PathwayBrowser/#/R-BTA-9749609 BCHE hydrolyzes ASA- IEA Bos taurus 13719 R-BTA-9749647 https://reactome.org/PathwayBrowser/#/R-BTA-9749647 CES2 hydrolyzes ASA- IEA Bos taurus 13719 R-BTA-9749792 https://reactome.org/PathwayBrowser/#/R-BTA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Bos taurus 13719 R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 13719 R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 13719 R-CEL-9749583 https://reactome.org/PathwayBrowser/#/R-CEL-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Caenorhabditis elegans 13719 R-CEL-9749607 https://reactome.org/PathwayBrowser/#/R-CEL-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Caenorhabditis elegans 13719 R-CEL-9749609 https://reactome.org/PathwayBrowser/#/R-CEL-9749609 BCHE hydrolyzes ASA- IEA Caenorhabditis elegans 13719 R-CEL-9749647 https://reactome.org/PathwayBrowser/#/R-CEL-9749647 CES2 hydrolyzes ASA- IEA Caenorhabditis elegans 13719 R-CEL-9749792 https://reactome.org/PathwayBrowser/#/R-CEL-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Caenorhabditis elegans 13719 R-CFA-2314678 https://reactome.org/PathwayBrowser/#/R-CFA-2314678 ASA- acetylates PTGS1 IEA Canis familiaris 13719 R-CFA-2314686 https://reactome.org/PathwayBrowser/#/R-CFA-2314686 ASA- acetylates PTGS2 IEA Canis familiaris 13719 R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 13719 R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 13719 R-CFA-9749590 https://reactome.org/PathwayBrowser/#/R-CFA-9749590 ASA- acetylates ALB IEA Canis familiaris 13719 R-CFA-9749607 https://reactome.org/PathwayBrowser/#/R-CFA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Canis familiaris 13719 R-CFA-9749609 https://reactome.org/PathwayBrowser/#/R-CFA-9749609 BCHE hydrolyzes ASA- IEA Canis familiaris 13719 R-CFA-9749647 https://reactome.org/PathwayBrowser/#/R-CFA-9749647 CES2 hydrolyzes ASA- IEA Canis familiaris 13719 R-CFA-9749792 https://reactome.org/PathwayBrowser/#/R-CFA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Canis familiaris 13719 R-DDI-9749647 https://reactome.org/PathwayBrowser/#/R-DDI-9749647 CES2 hydrolyzes ASA- IEA Dictyostelium discoideum 13719 R-DDI-9749792 https://reactome.org/PathwayBrowser/#/R-DDI-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Dictyostelium discoideum 13719 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 13719 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 13719 R-DME-9749583 https://reactome.org/PathwayBrowser/#/R-DME-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Drosophila melanogaster 13719 R-DME-9749607 https://reactome.org/PathwayBrowser/#/R-DME-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Drosophila melanogaster 13719 R-DME-9749609 https://reactome.org/PathwayBrowser/#/R-DME-9749609 BCHE hydrolyzes ASA- IEA Drosophila melanogaster 13719 R-DME-9749647 https://reactome.org/PathwayBrowser/#/R-DME-9749647 CES2 hydrolyzes ASA- IEA Drosophila melanogaster 13719 R-DME-9749792 https://reactome.org/PathwayBrowser/#/R-DME-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Drosophila melanogaster 13719 R-DRE-2314678 https://reactome.org/PathwayBrowser/#/R-DRE-2314678 ASA- acetylates PTGS1 IEA Danio rerio 13719 R-DRE-2314686 https://reactome.org/PathwayBrowser/#/R-DRE-2314686 ASA- acetylates PTGS2 IEA Danio rerio 13719 R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 13719 R-DRE-9749583 https://reactome.org/PathwayBrowser/#/R-DRE-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Danio rerio 13719 R-DRE-9749607 https://reactome.org/PathwayBrowser/#/R-DRE-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Danio rerio 13719 R-DRE-9749647 https://reactome.org/PathwayBrowser/#/R-DRE-9749647 CES2 hydrolyzes ASA- IEA Danio rerio 13719 R-DRE-9749792 https://reactome.org/PathwayBrowser/#/R-DRE-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Danio rerio 13719 R-GGA-2314678 https://reactome.org/PathwayBrowser/#/R-GGA-2314678 ASA- acetylates PTGS1 IEA Gallus gallus 13719 R-GGA-2314686 https://reactome.org/PathwayBrowser/#/R-GGA-2314686 ASA- acetylates PTGS2 IEA Gallus gallus 13719 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 13719 R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 13719 R-GGA-9749583 https://reactome.org/PathwayBrowser/#/R-GGA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Gallus gallus 13719 R-GGA-9749590 https://reactome.org/PathwayBrowser/#/R-GGA-9749590 ASA- acetylates ALB IEA Gallus gallus 13719 R-GGA-9749607 https://reactome.org/PathwayBrowser/#/R-GGA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Gallus gallus 13719 R-GGA-9749609 https://reactome.org/PathwayBrowser/#/R-GGA-9749609 BCHE hydrolyzes ASA- IEA Gallus gallus 13719 R-GGA-9749647 https://reactome.org/PathwayBrowser/#/R-GGA-9749647 CES2 hydrolyzes ASA- IEA Gallus gallus 13719 R-GGA-9749792 https://reactome.org/PathwayBrowser/#/R-GGA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Gallus gallus 13719 R-HSA-2314678 https://reactome.org/PathwayBrowser/#/R-HSA-2314678 ASA- acetylates PTGS1 TAS Homo sapiens 13719 R-HSA-2314686 https://reactome.org/PathwayBrowser/#/R-HSA-2314686 ASA- acetylates PTGS2 TAS Homo sapiens 13719 R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13719 R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13719 R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13719 R-HSA-9749583 https://reactome.org/PathwayBrowser/#/R-HSA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes TAS Homo sapiens 13719 R-HSA-9749590 https://reactome.org/PathwayBrowser/#/R-HSA-9749590 ASA- acetylates ALB TAS Homo sapiens 13719 R-HSA-9749607 https://reactome.org/PathwayBrowser/#/R-HSA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells TAS Homo sapiens 13719 R-HSA-9749609 https://reactome.org/PathwayBrowser/#/R-HSA-9749609 BCHE hydrolyzes ASA- TAS Homo sapiens 13719 R-HSA-9749647 https://reactome.org/PathwayBrowser/#/R-HSA-9749647 CES2 hydrolyzes ASA- TAS Homo sapiens 13719 R-HSA-9749792 https://reactome.org/PathwayBrowser/#/R-HSA-9749792 CES1,CES2 hydrolyze ASA- to ST TAS Homo sapiens 13719 R-HSA-9757434 https://reactome.org/PathwayBrowser/#/R-HSA-9757434 Acetylsalicylic acid dissolves TAS Homo sapiens 13719 R-HSA-9757438 https://reactome.org/PathwayBrowser/#/R-HSA-9757438 ASA- translocates from cytosol to ER lumen of GI cells TAS Homo sapiens 13719 R-HSA-9757441 https://reactome.org/PathwayBrowser/#/R-HSA-9757441 ASA- (GI) translocates from cytosol to extracellular region TAS Homo sapiens 13719 R-HSA-9757451 https://reactome.org/PathwayBrowser/#/R-HSA-9757451 ASA-,ST translocate from cytosol to ER lumen of hepatocytes TAS Homo sapiens 13719 R-MMU-2314678 https://reactome.org/PathwayBrowser/#/R-MMU-2314678 ASA- acetylates PTGS1 IEA Mus musculus 13719 R-MMU-2314686 https://reactome.org/PathwayBrowser/#/R-MMU-2314686 ASA- acetylates PTGS2 IEA Mus musculus 13719 R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 13719 R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 13719 R-MMU-9749583 https://reactome.org/PathwayBrowser/#/R-MMU-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Mus musculus 13719 R-MMU-9749590 https://reactome.org/PathwayBrowser/#/R-MMU-9749590 ASA- acetylates ALB IEA Mus musculus 13719 R-MMU-9749607 https://reactome.org/PathwayBrowser/#/R-MMU-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Mus musculus 13719 R-MMU-9749609 https://reactome.org/PathwayBrowser/#/R-MMU-9749609 BCHE hydrolyzes ASA- IEA Mus musculus 13719 R-MMU-9749647 https://reactome.org/PathwayBrowser/#/R-MMU-9749647 CES2 hydrolyzes ASA- IEA Mus musculus 13719 R-MMU-9749792 https://reactome.org/PathwayBrowser/#/R-MMU-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Mus musculus 13719 R-RNO-2314678 https://reactome.org/PathwayBrowser/#/R-RNO-2314678 ASA- acetylates PTGS1 IEA Rattus norvegicus 13719 R-RNO-2314686 https://reactome.org/PathwayBrowser/#/R-RNO-2314686 ASA- acetylates PTGS2 IEA Rattus norvegicus 13719 R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 13719 R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 13719 R-RNO-9749583 https://reactome.org/PathwayBrowser/#/R-RNO-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Rattus norvegicus 13719 R-RNO-9749590 https://reactome.org/PathwayBrowser/#/R-RNO-9749590 ASA- acetylates ALB IEA Rattus norvegicus 13719 R-RNO-9749607 https://reactome.org/PathwayBrowser/#/R-RNO-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Rattus norvegicus 13719 R-RNO-9749609 https://reactome.org/PathwayBrowser/#/R-RNO-9749609 BCHE hydrolyzes ASA- IEA Rattus norvegicus 13719 R-RNO-9749647 https://reactome.org/PathwayBrowser/#/R-RNO-9749647 CES2 hydrolyzes ASA- IEA Rattus norvegicus 13719 R-RNO-9749792 https://reactome.org/PathwayBrowser/#/R-RNO-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Rattus norvegicus 13719 R-SSC-2314678 https://reactome.org/PathwayBrowser/#/R-SSC-2314678 ASA- acetylates PTGS1 IEA Sus scrofa 13719 R-SSC-2314686 https://reactome.org/PathwayBrowser/#/R-SSC-2314686 ASA- acetylates PTGS2 IEA Sus scrofa 13719 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 13719 R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 13719 R-SSC-9749583 https://reactome.org/PathwayBrowser/#/R-SSC-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Sus scrofa 13719 R-SSC-9749590 https://reactome.org/PathwayBrowser/#/R-SSC-9749590 ASA- acetylates ALB IEA Sus scrofa 13719 R-SSC-9749607 https://reactome.org/PathwayBrowser/#/R-SSC-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Sus scrofa 13719 R-SSC-9749792 https://reactome.org/PathwayBrowser/#/R-SSC-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Sus scrofa 13719 R-XTR-2314678 https://reactome.org/PathwayBrowser/#/R-XTR-2314678 ASA- acetylates PTGS1 IEA Xenopus tropicalis 13719 R-XTR-2314686 https://reactome.org/PathwayBrowser/#/R-XTR-2314686 ASA- acetylates PTGS2 IEA Xenopus tropicalis 13719 R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 13719 R-XTR-9749590 https://reactome.org/PathwayBrowser/#/R-XTR-9749590 ASA- acetylates ALB IEA Xenopus tropicalis 13719 R-XTR-9749607 https://reactome.org/PathwayBrowser/#/R-XTR-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Xenopus tropicalis 13719 R-XTR-9749609 https://reactome.org/PathwayBrowser/#/R-XTR-9749609 BCHE hydrolyzes ASA- IEA Xenopus tropicalis 13719 R-XTR-9749792 https://reactome.org/PathwayBrowser/#/R-XTR-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Xenopus tropicalis 137218 R-HSA-110238 https://reactome.org/PathwayBrowser/#/R-HSA-110238 MPG glycosylase mediated recognition and binding of 3-methyladenine TAS Homo sapiens 137218 R-HSA-110248 https://reactome.org/PathwayBrowser/#/R-HSA-110248 Cleavage of 3-methyladenine by MPG glycosylase TAS Homo sapiens 137218 R-HSA-9730736 https://reactome.org/PathwayBrowser/#/R-HSA-9730736 Monofunctional chemotherapeutic alkylating drugs produce 3-methyladenine in dsDNA IEA Homo sapiens 137346 R-BTA-9027043 https://reactome.org/PathwayBrowser/#/R-BTA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Bos taurus 137346 R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 137346 R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans 137346 R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 137346 R-CFA-9027043 https://reactome.org/PathwayBrowser/#/R-CFA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Canis familiaris 137346 R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 137346 R-DDI-9027043 https://reactome.org/PathwayBrowser/#/R-DDI-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Dictyostelium discoideum 137346 R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 137346 R-DME-9027043 https://reactome.org/PathwayBrowser/#/R-DME-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Drosophila melanogaster 137346 R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 137346 R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio 137346 R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 137346 R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus 137346 R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 137346 R-HSA-9027043 https://reactome.org/PathwayBrowser/#/R-HSA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA TAS Homo sapiens 137346 R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 137346 R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 137346 R-MMU-9027043 https://reactome.org/PathwayBrowser/#/R-MMU-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Mus musculus 137346 R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 137346 R-RNO-9027043 https://reactome.org/PathwayBrowser/#/R-RNO-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Rattus norvegicus 137346 R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 137346 R-SSC-9027043 https://reactome.org/PathwayBrowser/#/R-SSC-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Sus scrofa 137346 R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 137346 R-XTR-9027043 https://reactome.org/PathwayBrowser/#/R-XTR-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Xenopus tropicalis 137346 R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 137347 R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 137347 R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 137347 R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 137347 R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 137347 R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 137347 R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 137347 R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 137347 R-HSA-9027033 https://reactome.org/PathwayBrowser/#/R-HSA-9027033 Hydroperoxy reducatase reduces 14(S)-Hp-DHA to 14(S)-HDHA TAS Homo sapiens 137347 R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 137347 R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 137347 R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 137347 R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 137347 R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 137347 R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 137349 R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 137349 R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 137350 R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 137350 R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 137354 R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 137354 R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 137354 R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 137354 R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 137354 R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 137354 R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 137354 R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 137354 R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 137354 R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 137354 R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 137354 R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 137354 R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 137354 R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 137360 R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 137360 R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 137360 R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 137360 R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 137360 R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 137360 R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 137360 R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 137360 R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 137360 R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 137360 R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 137360 R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 137360 R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 137360 R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 137361 R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 137361 R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 137361 R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 137361 R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 137361 R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 137361 R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 137361 R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 137361 R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 137361 R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 137361 R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 137361 R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 137361 R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 137361 R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 137368 R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 137368 R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 137368 R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 137368 R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 137368 R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 137368 R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 137368 R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 137368 R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 137368 R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 137368 R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 137368 R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 137368 R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 137368 R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 137376 R-MTU-9635428 https://reactome.org/PathwayBrowser/#/R-MTU-9635428 FadD26, FadD28 transfer LCFA adenylate ester to Pks5 TAS Mycobacterium tuberculosis 137376 R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 137376 R-MTU-9635480 https://reactome.org/PathwayBrowser/#/R-MTU-9635480 FadD26, FadD28 transfer adenylyl group to a LCFA TAS Mycobacterium tuberculosis 137981 R-BTA-73806 https://reactome.org/PathwayBrowser/#/R-BTA-73806 AIR + CO2 => CAIR IEA Bos taurus 137981 R-BTA-73810 https://reactome.org/PathwayBrowser/#/R-BTA-73810 FGAM + ATP => AIR + ADP + Pi IEA Bos taurus 137981 R-CEL-73806 https://reactome.org/PathwayBrowser/#/R-CEL-73806 AIR + CO2 => CAIR IEA Caenorhabditis elegans 137981 R-CEL-73810 https://reactome.org/PathwayBrowser/#/R-CEL-73810 FGAM + ATP => AIR + ADP + Pi IEA Caenorhabditis elegans 137981 R-CFA-73806 https://reactome.org/PathwayBrowser/#/R-CFA-73806 AIR + CO2 => CAIR IEA Canis familiaris 137981 R-CFA-73810 https://reactome.org/PathwayBrowser/#/R-CFA-73810 FGAM + ATP => AIR + ADP + Pi IEA Canis familiaris 137981 R-DDI-73810 https://reactome.org/PathwayBrowser/#/R-DDI-73810 FGAM + ATP => AIR + ADP + Pi IEA Dictyostelium discoideum 137981 R-DME-73806 https://reactome.org/PathwayBrowser/#/R-DME-73806 AIR + CO2 => CAIR IEA Drosophila melanogaster 137981 R-DME-73810 https://reactome.org/PathwayBrowser/#/R-DME-73810 FGAM + ATP => AIR + ADP + Pi IEA Drosophila melanogaster 137981 R-DRE-73806 https://reactome.org/PathwayBrowser/#/R-DRE-73806 AIR + CO2 => CAIR IEA Danio rerio 137981 R-DRE-73810 https://reactome.org/PathwayBrowser/#/R-DRE-73810 FGAM + ATP => AIR + ADP + Pi IEA Danio rerio 137981 R-GGA-419157 https://reactome.org/PathwayBrowser/#/R-GGA-419157 5'-phosphoribosylformylglycinamidine (FGAM) + ATP => 5'-phosphoribosyl-5-aminoimidazole (AIR) + ADP + orthophosphate TAS Gallus gallus 137981 R-GGA-419214 https://reactome.org/PathwayBrowser/#/R-GGA-419214 5'-phosphoribosyl-5-aminoimidazole (AIR) + CO2 <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) TAS Gallus gallus 137981 R-GGA-73806 https://reactome.org/PathwayBrowser/#/R-GGA-73806 AIR + CO2 => CAIR IEA Gallus gallus 137981 R-GGA-73810 https://reactome.org/PathwayBrowser/#/R-GGA-73810 FGAM + ATP => AIR + ADP + Pi IEA Gallus gallus 137981 R-HSA-73806 https://reactome.org/PathwayBrowser/#/R-HSA-73806 AIR + CO2 => CAIR TAS Homo sapiens 137981 R-HSA-73810 https://reactome.org/PathwayBrowser/#/R-HSA-73810 FGAM + ATP => AIR + ADP + Pi TAS Homo sapiens 137981 R-MMU-73806 https://reactome.org/PathwayBrowser/#/R-MMU-73806 AIR + CO2 => CAIR IEA Mus musculus 137981 R-MMU-73810 https://reactome.org/PathwayBrowser/#/R-MMU-73810 FGAM + ATP => AIR + ADP + Pi IEA Mus musculus 137981 R-RNO-73806 https://reactome.org/PathwayBrowser/#/R-RNO-73806 AIR + CO2 => CAIR IEA Rattus norvegicus 137981 R-RNO-73810 https://reactome.org/PathwayBrowser/#/R-RNO-73810 FGAM + ATP => AIR + ADP + Pi IEA Rattus norvegicus 137981 R-SCE-73810 https://reactome.org/PathwayBrowser/#/R-SCE-73810 FGAM + ATP => AIR + ADP + Pi IEA Saccharomyces cerevisiae 137981 R-SPO-73810 https://reactome.org/PathwayBrowser/#/R-SPO-73810 FGAM + ATP => AIR + ADP + Pi IEA Schizosaccharomyces pombe 137981 R-SSC-73806 https://reactome.org/PathwayBrowser/#/R-SSC-73806 AIR + CO2 => CAIR IEA Sus scrofa 137981 R-SSC-73810 https://reactome.org/PathwayBrowser/#/R-SSC-73810 FGAM + ATP => AIR + ADP + Pi IEA Sus scrofa 137981 R-XTR-73806 https://reactome.org/PathwayBrowser/#/R-XTR-73806 AIR + CO2 => CAIR IEA Xenopus tropicalis 137981 R-XTR-73810 https://reactome.org/PathwayBrowser/#/R-XTR-73810 FGAM + ATP => AIR + ADP + Pi IEA Xenopus tropicalis 138170 R-BTA-9013533 https://reactome.org/PathwayBrowser/#/R-BTA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Bos taurus 138170 R-CEL-9013533 https://reactome.org/PathwayBrowser/#/R-CEL-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Caenorhabditis elegans 138170 R-CFA-9013533 https://reactome.org/PathwayBrowser/#/R-CFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Canis familiaris 138170 R-DDI-9013533 https://reactome.org/PathwayBrowser/#/R-DDI-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Dictyostelium discoideum 138170 R-DRE-9013533 https://reactome.org/PathwayBrowser/#/R-DRE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Danio rerio 138170 R-GGA-9013533 https://reactome.org/PathwayBrowser/#/R-GGA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Gallus gallus 138170 R-HSA-9013533 https://reactome.org/PathwayBrowser/#/R-HSA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN TAS Homo sapiens 138170 R-MMU-9013533 https://reactome.org/PathwayBrowser/#/R-MMU-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Mus musculus 138170 R-PFA-9013533 https://reactome.org/PathwayBrowser/#/R-PFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Plasmodium falciparum 138170 R-RNO-9013533 https://reactome.org/PathwayBrowser/#/R-RNO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Rattus norvegicus 138170 R-SCE-9013533 https://reactome.org/PathwayBrowser/#/R-SCE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Saccharomyces cerevisiae 138170 R-SPO-9013533 https://reactome.org/PathwayBrowser/#/R-SPO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Schizosaccharomyces pombe 138170 R-SSC-9013533 https://reactome.org/PathwayBrowser/#/R-SSC-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Sus scrofa 138170 R-XTR-9013533 https://reactome.org/PathwayBrowser/#/R-XTR-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Xenopus tropicalis 138179 R-BTA-9020252 https://reactome.org/PathwayBrowser/#/R-BTA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Bos taurus 138179 R-CEL-9020252 https://reactome.org/PathwayBrowser/#/R-CEL-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Caenorhabditis elegans 138179 R-CFA-9020252 https://reactome.org/PathwayBrowser/#/R-CFA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Canis familiaris 138179 R-DDI-9020252 https://reactome.org/PathwayBrowser/#/R-DDI-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Dictyostelium discoideum 138179 R-DME-9020252 https://reactome.org/PathwayBrowser/#/R-DME-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Drosophila melanogaster 138179 R-DRE-9020252 https://reactome.org/PathwayBrowser/#/R-DRE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Danio rerio 138179 R-GGA-9020252 https://reactome.org/PathwayBrowser/#/R-GGA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Gallus gallus 138179 R-HSA-9020252 https://reactome.org/PathwayBrowser/#/R-HSA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 TAS Homo sapiens 138179 R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138179 R-MMU-9020252 https://reactome.org/PathwayBrowser/#/R-MMU-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Mus musculus 138179 R-RNO-9020252 https://reactome.org/PathwayBrowser/#/R-RNO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Rattus norvegicus 138179 R-SCE-9020252 https://reactome.org/PathwayBrowser/#/R-SCE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Saccharomyces cerevisiae 138179 R-SPO-9020252 https://reactome.org/PathwayBrowser/#/R-SPO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Schizosaccharomyces pombe 138179 R-SSC-9020252 https://reactome.org/PathwayBrowser/#/R-SSC-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Sus scrofa 138179 R-XTR-9020252 https://reactome.org/PathwayBrowser/#/R-XTR-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Xenopus tropicalis 138202 R-BTA-9026777 https://reactome.org/PathwayBrowser/#/R-BTA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Bos taurus 138202 R-BTA-9026780 https://reactome.org/PathwayBrowser/#/R-BTA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Bos taurus 138202 R-CFA-9026777 https://reactome.org/PathwayBrowser/#/R-CFA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Canis familiaris 138202 R-CFA-9026780 https://reactome.org/PathwayBrowser/#/R-CFA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Canis familiaris 138202 R-DDI-9026780 https://reactome.org/PathwayBrowser/#/R-DDI-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Dictyostelium discoideum 138202 R-DRE-9026777 https://reactome.org/PathwayBrowser/#/R-DRE-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Danio rerio 138202 R-GGA-9026777 https://reactome.org/PathwayBrowser/#/R-GGA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Gallus gallus 138202 R-GGA-9026780 https://reactome.org/PathwayBrowser/#/R-GGA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Gallus gallus 138202 R-HSA-9026757 https://reactome.org/PathwayBrowser/#/R-HSA-9026757 GGT hydrolyses MCTR1 to MCTR2 TAS Homo sapiens 138202 R-HSA-9026777 https://reactome.org/PathwayBrowser/#/R-HSA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 TAS Homo sapiens 138202 R-HSA-9026780 https://reactome.org/PathwayBrowser/#/R-HSA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 TAS Homo sapiens 138202 R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 138202 R-MMU-9026777 https://reactome.org/PathwayBrowser/#/R-MMU-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Mus musculus 138202 R-MMU-9026780 https://reactome.org/PathwayBrowser/#/R-MMU-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Mus musculus 138202 R-RNO-9026777 https://reactome.org/PathwayBrowser/#/R-RNO-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Rattus norvegicus 138202 R-RNO-9026780 https://reactome.org/PathwayBrowser/#/R-RNO-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Rattus norvegicus 138202 R-SSC-9026777 https://reactome.org/PathwayBrowser/#/R-SSC-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Sus scrofa 138202 R-SSC-9026780 https://reactome.org/PathwayBrowser/#/R-SSC-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Sus scrofa 138202 R-XTR-9026777 https://reactome.org/PathwayBrowser/#/R-XTR-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Xenopus tropicalis 138202 R-XTR-9026780 https://reactome.org/PathwayBrowser/#/R-XTR-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Xenopus tropicalis 138206 R-HSA-9026757 https://reactome.org/PathwayBrowser/#/R-HSA-9026757 GGT hydrolyses MCTR1 to MCTR2 TAS Homo sapiens 138206 R-HSA-9026771 https://reactome.org/PathwayBrowser/#/R-HSA-9026771 DPEP hydrolyses MCTR2 to MCTR3 TAS Homo sapiens 138206 R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 138209 R-HSA-9026771 https://reactome.org/PathwayBrowser/#/R-HSA-9026771 DPEP hydrolyses MCTR2 to MCTR3 TAS Homo sapiens 138209 R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 138248 R-BTA-9024993 https://reactome.org/PathwayBrowser/#/R-BTA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Bos taurus 138248 R-CFA-9024993 https://reactome.org/PathwayBrowser/#/R-CFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Canis familiaris 138248 R-DDI-9024993 https://reactome.org/PathwayBrowser/#/R-DDI-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Dictyostelium discoideum 138248 R-DRE-9024993 https://reactome.org/PathwayBrowser/#/R-DRE-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Danio rerio 138248 R-GGA-9024993 https://reactome.org/PathwayBrowser/#/R-GGA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Gallus gallus 138248 R-HSA-9024993 https://reactome.org/PathwayBrowser/#/R-HSA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 TAS Homo sapiens 138248 R-HSA-9031802 https://reactome.org/PathwayBrowser/#/R-HSA-9031802 Maresins translocate from cytosol to extracellular region TAS Homo sapiens 138248 R-MMU-9024993 https://reactome.org/PathwayBrowser/#/R-MMU-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Mus musculus 138248 R-PFA-9024993 https://reactome.org/PathwayBrowser/#/R-PFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Plasmodium falciparum 138248 R-RNO-9024993 https://reactome.org/PathwayBrowser/#/R-RNO-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Rattus norvegicus 138248 R-SSC-9024993 https://reactome.org/PathwayBrowser/#/R-SSC-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Sus scrofa 138248 R-XTR-9024993 https://reactome.org/PathwayBrowser/#/R-XTR-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Xenopus tropicalis 138249 R-HSA-9024973 https://reactome.org/PathwayBrowser/#/R-HSA-9024973 Epoxide hydrolase hydrolyses 13(S),14(S)-epoxy-DHA to MaR1 TAS Homo sapiens 138249 R-HSA-9031802 https://reactome.org/PathwayBrowser/#/R-HSA-9031802 Maresins translocate from cytosol to extracellular region TAS Homo sapiens 138387 R-BTA-9018868 https://reactome.org/PathwayBrowser/#/R-BTA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Bos taurus 138387 R-BTA-9018880 https://reactome.org/PathwayBrowser/#/R-BTA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Bos taurus 138387 R-CEL-9018868 https://reactome.org/PathwayBrowser/#/R-CEL-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Caenorhabditis elegans 138387 R-CFA-9018868 https://reactome.org/PathwayBrowser/#/R-CFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Canis familiaris 138387 R-CFA-9018880 https://reactome.org/PathwayBrowser/#/R-CFA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Canis familiaris 138387 R-DRE-9018880 https://reactome.org/PathwayBrowser/#/R-DRE-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Danio rerio 138387 R-GGA-9018868 https://reactome.org/PathwayBrowser/#/R-GGA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Gallus gallus 138387 R-GGA-9018880 https://reactome.org/PathwayBrowser/#/R-GGA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Gallus gallus 138387 R-HSA-9018868 https://reactome.org/PathwayBrowser/#/R-HSA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE TAS Homo sapiens 138387 R-HSA-9018874 https://reactome.org/PathwayBrowser/#/R-HSA-9018874 CYP monooxygenates EPA to 18(S)-HpEPE TAS Homo sapiens 138387 R-HSA-9018880 https://reactome.org/PathwayBrowser/#/R-HSA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE TAS Homo sapiens 138387 R-MMU-9018868 https://reactome.org/PathwayBrowser/#/R-MMU-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Mus musculus 138387 R-MMU-9018880 https://reactome.org/PathwayBrowser/#/R-MMU-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Mus musculus 138387 R-PFA-9018868 https://reactome.org/PathwayBrowser/#/R-PFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Plasmodium falciparum 138387 R-RNO-9018868 https://reactome.org/PathwayBrowser/#/R-RNO-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Rattus norvegicus 138387 R-RNO-9018880 https://reactome.org/PathwayBrowser/#/R-RNO-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Rattus norvegicus 138387 R-SSC-9018868 https://reactome.org/PathwayBrowser/#/R-SSC-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Sus scrofa 138387 R-SSC-9018880 https://reactome.org/PathwayBrowser/#/R-SSC-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Sus scrofa 138387 R-XTR-9018880 https://reactome.org/PathwayBrowser/#/R-XTR-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Xenopus tropicalis 138412 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 138412 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 138412 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 138412 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 138412 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 138412 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 138412 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 138412 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 138412 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 138412 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 138477 R-BTA-9020610 https://reactome.org/PathwayBrowser/#/R-BTA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Bos taurus 138477 R-CFA-9020610 https://reactome.org/PathwayBrowser/#/R-CFA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Canis familiaris 138477 R-DDI-9020610 https://reactome.org/PathwayBrowser/#/R-DDI-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Dictyostelium discoideum 138477 R-DRE-9020610 https://reactome.org/PathwayBrowser/#/R-DRE-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Danio rerio 138477 R-HSA-9020610 https://reactome.org/PathwayBrowser/#/R-HSA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 TAS Homo sapiens 138477 R-HSA-9023980 https://reactome.org/PathwayBrowser/#/R-HSA-9023980 18(S)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 138477 R-MMU-9020610 https://reactome.org/PathwayBrowser/#/R-MMU-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Mus musculus 138477 R-RNO-9020610 https://reactome.org/PathwayBrowser/#/R-RNO-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Rattus norvegicus 138477 R-SSC-9020610 https://reactome.org/PathwayBrowser/#/R-SSC-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Sus scrofa 138490 R-BTA-9018859 https://reactome.org/PathwayBrowser/#/R-BTA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Bos taurus 138490 R-BTA-9018862 https://reactome.org/PathwayBrowser/#/R-BTA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Bos taurus 138490 R-CEL-9018862 https://reactome.org/PathwayBrowser/#/R-CEL-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Caenorhabditis elegans 138490 R-CFA-9018859 https://reactome.org/PathwayBrowser/#/R-CFA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Canis familiaris 138490 R-CFA-9018862 https://reactome.org/PathwayBrowser/#/R-CFA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Canis familiaris 138490 R-DDI-9018859 https://reactome.org/PathwayBrowser/#/R-DDI-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Dictyostelium discoideum 138490 R-DDI-9018862 https://reactome.org/PathwayBrowser/#/R-DDI-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Dictyostelium discoideum 138490 R-DME-9018862 https://reactome.org/PathwayBrowser/#/R-DME-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Drosophila melanogaster 138490 R-DRE-9018859 https://reactome.org/PathwayBrowser/#/R-DRE-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Danio rerio 138490 R-DRE-9018862 https://reactome.org/PathwayBrowser/#/R-DRE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Danio rerio 138490 R-GGA-9018859 https://reactome.org/PathwayBrowser/#/R-GGA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Gallus gallus 138490 R-GGA-9018862 https://reactome.org/PathwayBrowser/#/R-GGA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Gallus gallus 138490 R-HSA-9018859 https://reactome.org/PathwayBrowser/#/R-HSA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE TAS Homo sapiens 138490 R-HSA-9018862 https://reactome.org/PathwayBrowser/#/R-HSA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 TAS Homo sapiens 138490 R-MMU-9018859 https://reactome.org/PathwayBrowser/#/R-MMU-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Mus musculus 138490 R-MMU-9018862 https://reactome.org/PathwayBrowser/#/R-MMU-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Mus musculus 138490 R-RNO-9018859 https://reactome.org/PathwayBrowser/#/R-RNO-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Rattus norvegicus 138490 R-RNO-9018862 https://reactome.org/PathwayBrowser/#/R-RNO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Rattus norvegicus 138490 R-SCE-9018862 https://reactome.org/PathwayBrowser/#/R-SCE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Saccharomyces cerevisiae 138490 R-SPO-9018862 https://reactome.org/PathwayBrowser/#/R-SPO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Schizosaccharomyces pombe 138490 R-SSC-9018859 https://reactome.org/PathwayBrowser/#/R-SSC-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Sus scrofa 138490 R-SSC-9018862 https://reactome.org/PathwayBrowser/#/R-SSC-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Sus scrofa 138490 R-XTR-9018859 https://reactome.org/PathwayBrowser/#/R-XTR-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Xenopus tropicalis 138490 R-XTR-9018862 https://reactome.org/PathwayBrowser/#/R-XTR-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Xenopus tropicalis 138542 R-BTA-9018907 https://reactome.org/PathwayBrowser/#/R-BTA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Bos taurus 138542 R-CFA-9018907 https://reactome.org/PathwayBrowser/#/R-CFA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Canis familiaris 138542 R-DDI-9018907 https://reactome.org/PathwayBrowser/#/R-DDI-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Dictyostelium discoideum 138542 R-DRE-9018907 https://reactome.org/PathwayBrowser/#/R-DRE-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Danio rerio 138542 R-HSA-9018907 https://reactome.org/PathwayBrowser/#/R-HSA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 TAS Homo sapiens 138542 R-HSA-9023983 https://reactome.org/PathwayBrowser/#/R-HSA-9023983 18(R)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 138542 R-MMU-9018907 https://reactome.org/PathwayBrowser/#/R-MMU-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Mus musculus 138542 R-RNO-9018907 https://reactome.org/PathwayBrowser/#/R-RNO-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Rattus norvegicus 138542 R-SSC-9018907 https://reactome.org/PathwayBrowser/#/R-SSC-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Sus scrofa 138563 R-BTA-9018877 https://reactome.org/PathwayBrowser/#/R-BTA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Bos taurus 138563 R-BTA-9018894 https://reactome.org/PathwayBrowser/#/R-BTA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Bos taurus 138563 R-CEL-9018877 https://reactome.org/PathwayBrowser/#/R-CEL-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Caenorhabditis elegans 138563 R-CFA-9018877 https://reactome.org/PathwayBrowser/#/R-CFA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Canis familiaris 138563 R-CFA-9018894 https://reactome.org/PathwayBrowser/#/R-CFA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Canis familiaris 138563 R-DDI-9018877 https://reactome.org/PathwayBrowser/#/R-DDI-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Dictyostelium discoideum 138563 R-DDI-9018894 https://reactome.org/PathwayBrowser/#/R-DDI-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Dictyostelium discoideum 138563 R-DME-9018877 https://reactome.org/PathwayBrowser/#/R-DME-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Drosophila melanogaster 138563 R-DRE-9018877 https://reactome.org/PathwayBrowser/#/R-DRE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Danio rerio 138563 R-DRE-9018894 https://reactome.org/PathwayBrowser/#/R-DRE-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Danio rerio 138563 R-GGA-9018877 https://reactome.org/PathwayBrowser/#/R-GGA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Gallus gallus 138563 R-GGA-9018894 https://reactome.org/PathwayBrowser/#/R-GGA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Gallus gallus 138563 R-HSA-9018877 https://reactome.org/PathwayBrowser/#/R-HSA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 TAS Homo sapiens 138563 R-HSA-9018894 https://reactome.org/PathwayBrowser/#/R-HSA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE TAS Homo sapiens 138563 R-MMU-9018877 https://reactome.org/PathwayBrowser/#/R-MMU-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Mus musculus 138563 R-MMU-9018894 https://reactome.org/PathwayBrowser/#/R-MMU-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Mus musculus 138563 R-RNO-9018877 https://reactome.org/PathwayBrowser/#/R-RNO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Rattus norvegicus 138563 R-RNO-9018894 https://reactome.org/PathwayBrowser/#/R-RNO-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Rattus norvegicus 138563 R-SCE-9018877 https://reactome.org/PathwayBrowser/#/R-SCE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Saccharomyces cerevisiae 138563 R-SPO-9018877 https://reactome.org/PathwayBrowser/#/R-SPO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Schizosaccharomyces pombe 138563 R-SSC-9018877 https://reactome.org/PathwayBrowser/#/R-SSC-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Sus scrofa 138563 R-SSC-9018894 https://reactome.org/PathwayBrowser/#/R-SSC-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Sus scrofa 138563 R-XTR-9018877 https://reactome.org/PathwayBrowser/#/R-XTR-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Xenopus tropicalis 138563 R-XTR-9018894 https://reactome.org/PathwayBrowser/#/R-XTR-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Xenopus tropicalis 138565 R-BTA-9018880 https://reactome.org/PathwayBrowser/#/R-BTA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Bos taurus 138565 R-BTA-9018895 https://reactome.org/PathwayBrowser/#/R-BTA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Bos taurus 138565 R-CEL-9018895 https://reactome.org/PathwayBrowser/#/R-CEL-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Caenorhabditis elegans 138565 R-CFA-9018880 https://reactome.org/PathwayBrowser/#/R-CFA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Canis familiaris 138565 R-CFA-9018895 https://reactome.org/PathwayBrowser/#/R-CFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Canis familiaris 138565 R-DRE-9018880 https://reactome.org/PathwayBrowser/#/R-DRE-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Danio rerio 138565 R-GGA-9018880 https://reactome.org/PathwayBrowser/#/R-GGA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Gallus gallus 138565 R-GGA-9018895 https://reactome.org/PathwayBrowser/#/R-GGA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Gallus gallus 138565 R-HSA-9018880 https://reactome.org/PathwayBrowser/#/R-HSA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE TAS Homo sapiens 138565 R-HSA-9018895 https://reactome.org/PathwayBrowser/#/R-HSA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE TAS Homo sapiens 138565 R-MMU-9018880 https://reactome.org/PathwayBrowser/#/R-MMU-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Mus musculus 138565 R-MMU-9018895 https://reactome.org/PathwayBrowser/#/R-MMU-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Mus musculus 138565 R-PFA-9018895 https://reactome.org/PathwayBrowser/#/R-PFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Plasmodium falciparum 138565 R-RNO-9018880 https://reactome.org/PathwayBrowser/#/R-RNO-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Rattus norvegicus 138565 R-RNO-9018895 https://reactome.org/PathwayBrowser/#/R-RNO-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Rattus norvegicus 138565 R-SSC-9018880 https://reactome.org/PathwayBrowser/#/R-SSC-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Sus scrofa 138565 R-SSC-9018895 https://reactome.org/PathwayBrowser/#/R-SSC-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Sus scrofa 138565 R-XTR-9018880 https://reactome.org/PathwayBrowser/#/R-XTR-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Xenopus tropicalis 138590 R-BTA-9020261 https://reactome.org/PathwayBrowser/#/R-BTA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Bos taurus 138590 R-BTA-9020262 https://reactome.org/PathwayBrowser/#/R-BTA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Bos taurus 138590 R-BTA-9020271 https://reactome.org/PathwayBrowser/#/R-BTA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Bos taurus 138590 R-CEL-9020271 https://reactome.org/PathwayBrowser/#/R-CEL-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Caenorhabditis elegans 138590 R-CFA-9020261 https://reactome.org/PathwayBrowser/#/R-CFA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Canis familiaris 138590 R-CFA-9020262 https://reactome.org/PathwayBrowser/#/R-CFA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Canis familiaris 138590 R-CFA-9020271 https://reactome.org/PathwayBrowser/#/R-CFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Canis familiaris 138590 R-DDI-9020262 https://reactome.org/PathwayBrowser/#/R-DDI-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Dictyostelium discoideum 138590 R-DRE-9020261 https://reactome.org/PathwayBrowser/#/R-DRE-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Danio rerio 138590 R-DRE-9020262 https://reactome.org/PathwayBrowser/#/R-DRE-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Danio rerio 138590 R-GGA-9020261 https://reactome.org/PathwayBrowser/#/R-GGA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Gallus gallus 138590 R-GGA-9020271 https://reactome.org/PathwayBrowser/#/R-GGA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Gallus gallus 138590 R-HSA-9020261 https://reactome.org/PathwayBrowser/#/R-HSA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA TAS Homo sapiens 138590 R-HSA-9020262 https://reactome.org/PathwayBrowser/#/R-HSA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA TAS Homo sapiens 138590 R-HSA-9020271 https://reactome.org/PathwayBrowser/#/R-HSA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA TAS Homo sapiens 138590 R-MMU-9020261 https://reactome.org/PathwayBrowser/#/R-MMU-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Mus musculus 138590 R-MMU-9020262 https://reactome.org/PathwayBrowser/#/R-MMU-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Mus musculus 138590 R-MMU-9020271 https://reactome.org/PathwayBrowser/#/R-MMU-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Mus musculus 138590 R-PFA-9020271 https://reactome.org/PathwayBrowser/#/R-PFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Plasmodium falciparum 138590 R-RNO-9020261 https://reactome.org/PathwayBrowser/#/R-RNO-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Rattus norvegicus 138590 R-RNO-9020262 https://reactome.org/PathwayBrowser/#/R-RNO-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Rattus norvegicus 138590 R-RNO-9020271 https://reactome.org/PathwayBrowser/#/R-RNO-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Rattus norvegicus 138590 R-SSC-9020261 https://reactome.org/PathwayBrowser/#/R-SSC-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Sus scrofa 138590 R-SSC-9020262 https://reactome.org/PathwayBrowser/#/R-SSC-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Sus scrofa 138590 R-SSC-9020271 https://reactome.org/PathwayBrowser/#/R-SSC-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Sus scrofa 138590 R-XTR-9020261 https://reactome.org/PathwayBrowser/#/R-XTR-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Xenopus tropicalis 138601 R-BTA-9020259 https://reactome.org/PathwayBrowser/#/R-BTA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Bos taurus 138601 R-BTA-9020278 https://reactome.org/PathwayBrowser/#/R-BTA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Bos taurus 138601 R-CFA-9020259 https://reactome.org/PathwayBrowser/#/R-CFA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Canis familiaris 138601 R-CFA-9020278 https://reactome.org/PathwayBrowser/#/R-CFA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Canis familiaris 138601 R-DDI-9020259 https://reactome.org/PathwayBrowser/#/R-DDI-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Dictyostelium discoideum 138601 R-DDI-9020278 https://reactome.org/PathwayBrowser/#/R-DDI-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Dictyostelium discoideum 138601 R-DRE-9020259 https://reactome.org/PathwayBrowser/#/R-DRE-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Danio rerio 138601 R-DRE-9020278 https://reactome.org/PathwayBrowser/#/R-DRE-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Danio rerio 138601 R-GGA-9020259 https://reactome.org/PathwayBrowser/#/R-GGA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Gallus gallus 138601 R-GGA-9020278 https://reactome.org/PathwayBrowser/#/R-GGA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Gallus gallus 138601 R-HSA-9020259 https://reactome.org/PathwayBrowser/#/R-HSA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA TAS Homo sapiens 138601 R-HSA-9020278 https://reactome.org/PathwayBrowser/#/R-HSA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA TAS Homo sapiens 138601 R-HSA-9024624 https://reactome.org/PathwayBrowser/#/R-HSA-9024624 Hydroperoxy reductase reduces 4(S)-Hp-17(R)-HDHA to AT-RvD6 TAS Homo sapiens 138601 R-MMU-9020259 https://reactome.org/PathwayBrowser/#/R-MMU-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Mus musculus 138601 R-MMU-9020278 https://reactome.org/PathwayBrowser/#/R-MMU-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Mus musculus 138601 R-RNO-9020259 https://reactome.org/PathwayBrowser/#/R-RNO-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Rattus norvegicus 138601 R-RNO-9020278 https://reactome.org/PathwayBrowser/#/R-RNO-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Rattus norvegicus 138601 R-SSC-9020259 https://reactome.org/PathwayBrowser/#/R-SSC-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Sus scrofa 138601 R-SSC-9020278 https://reactome.org/PathwayBrowser/#/R-SSC-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Sus scrofa 138601 R-XTR-9020259 https://reactome.org/PathwayBrowser/#/R-XTR-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Xenopus tropicalis 138601 R-XTR-9020278 https://reactome.org/PathwayBrowser/#/R-XTR-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Xenopus tropicalis 138602 R-BTA-9020251 https://reactome.org/PathwayBrowser/#/R-BTA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Bos taurus 138602 R-BTA-9020256 https://reactome.org/PathwayBrowser/#/R-BTA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Bos taurus 138602 R-CFA-9020251 https://reactome.org/PathwayBrowser/#/R-CFA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Canis familiaris 138602 R-CFA-9020256 https://reactome.org/PathwayBrowser/#/R-CFA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Canis familiaris 138602 R-DDI-9020251 https://reactome.org/PathwayBrowser/#/R-DDI-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Dictyostelium discoideum 138602 R-DDI-9020256 https://reactome.org/PathwayBrowser/#/R-DDI-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Dictyostelium discoideum 138602 R-DRE-9020251 https://reactome.org/PathwayBrowser/#/R-DRE-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Danio rerio 138602 R-DRE-9020256 https://reactome.org/PathwayBrowser/#/R-DRE-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Danio rerio 138602 R-GGA-9020251 https://reactome.org/PathwayBrowser/#/R-GGA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Gallus gallus 138602 R-GGA-9020256 https://reactome.org/PathwayBrowser/#/R-GGA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Gallus gallus 138602 R-HSA-9020251 https://reactome.org/PathwayBrowser/#/R-HSA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA TAS Homo sapiens 138602 R-HSA-9020256 https://reactome.org/PathwayBrowser/#/R-HSA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA TAS Homo sapiens 138602 R-HSA-9024630 https://reactome.org/PathwayBrowser/#/R-HSA-9024630 Hydroperoxy reductase reduces 7(S)-Hp-17(R)-HDHA to AT-RvD5 TAS Homo sapiens 138602 R-MMU-9020251 https://reactome.org/PathwayBrowser/#/R-MMU-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Mus musculus 138602 R-MMU-9020256 https://reactome.org/PathwayBrowser/#/R-MMU-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Mus musculus 138602 R-RNO-9020251 https://reactome.org/PathwayBrowser/#/R-RNO-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Rattus norvegicus 138602 R-RNO-9020256 https://reactome.org/PathwayBrowser/#/R-RNO-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Rattus norvegicus 138602 R-SSC-9020251 https://reactome.org/PathwayBrowser/#/R-SSC-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Sus scrofa 138602 R-SSC-9020256 https://reactome.org/PathwayBrowser/#/R-SSC-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Sus scrofa 138602 R-XTR-9020251 https://reactome.org/PathwayBrowser/#/R-XTR-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Xenopus tropicalis 138602 R-XTR-9020256 https://reactome.org/PathwayBrowser/#/R-XTR-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Xenopus tropicalis 138612 R-BTA-9020270 https://reactome.org/PathwayBrowser/#/R-BTA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Bos taurus 138612 R-BTA-9020278 https://reactome.org/PathwayBrowser/#/R-BTA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Bos taurus 138612 R-CEL-9020270 https://reactome.org/PathwayBrowser/#/R-CEL-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Caenorhabditis elegans 138612 R-CFA-9020270 https://reactome.org/PathwayBrowser/#/R-CFA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Canis familiaris 138612 R-CFA-9020278 https://reactome.org/PathwayBrowser/#/R-CFA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Canis familiaris 138612 R-DDI-9020270 https://reactome.org/PathwayBrowser/#/R-DDI-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Dictyostelium discoideum 138612 R-DDI-9020278 https://reactome.org/PathwayBrowser/#/R-DDI-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Dictyostelium discoideum 138612 R-DME-9020270 https://reactome.org/PathwayBrowser/#/R-DME-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Drosophila melanogaster 138612 R-DRE-9020270 https://reactome.org/PathwayBrowser/#/R-DRE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Danio rerio 138612 R-DRE-9020278 https://reactome.org/PathwayBrowser/#/R-DRE-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Danio rerio 138612 R-GGA-9020270 https://reactome.org/PathwayBrowser/#/R-GGA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Gallus gallus 138612 R-GGA-9020278 https://reactome.org/PathwayBrowser/#/R-GGA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Gallus gallus 138612 R-HSA-9020270 https://reactome.org/PathwayBrowser/#/R-HSA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 TAS Homo sapiens 138612 R-HSA-9020278 https://reactome.org/PathwayBrowser/#/R-HSA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA TAS Homo sapiens 138612 R-MMU-9020270 https://reactome.org/PathwayBrowser/#/R-MMU-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Mus musculus 138612 R-MMU-9020278 https://reactome.org/PathwayBrowser/#/R-MMU-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Mus musculus 138612 R-RNO-9020270 https://reactome.org/PathwayBrowser/#/R-RNO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Rattus norvegicus 138612 R-RNO-9020278 https://reactome.org/PathwayBrowser/#/R-RNO-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Rattus norvegicus 138612 R-SCE-9020270 https://reactome.org/PathwayBrowser/#/R-SCE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Saccharomyces cerevisiae 138612 R-SPO-9020270 https://reactome.org/PathwayBrowser/#/R-SPO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Schizosaccharomyces pombe 138612 R-SSC-9020270 https://reactome.org/PathwayBrowser/#/R-SSC-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Sus scrofa 138612 R-SSC-9020278 https://reactome.org/PathwayBrowser/#/R-SSC-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Sus scrofa 138612 R-XTR-9020270 https://reactome.org/PathwayBrowser/#/R-XTR-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Xenopus tropicalis 138612 R-XTR-9020278 https://reactome.org/PathwayBrowser/#/R-XTR-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Xenopus tropicalis 138613 R-BTA-9020252 https://reactome.org/PathwayBrowser/#/R-BTA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Bos taurus 138613 R-BTA-9020256 https://reactome.org/PathwayBrowser/#/R-BTA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Bos taurus 138613 R-CEL-9020252 https://reactome.org/PathwayBrowser/#/R-CEL-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Caenorhabditis elegans 138613 R-CFA-9020252 https://reactome.org/PathwayBrowser/#/R-CFA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Canis familiaris 138613 R-CFA-9020256 https://reactome.org/PathwayBrowser/#/R-CFA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Canis familiaris 138613 R-DDI-9020252 https://reactome.org/PathwayBrowser/#/R-DDI-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Dictyostelium discoideum 138613 R-DDI-9020256 https://reactome.org/PathwayBrowser/#/R-DDI-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Dictyostelium discoideum 138613 R-DME-9020252 https://reactome.org/PathwayBrowser/#/R-DME-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Drosophila melanogaster 138613 R-DRE-9020252 https://reactome.org/PathwayBrowser/#/R-DRE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Danio rerio 138613 R-DRE-9020256 https://reactome.org/PathwayBrowser/#/R-DRE-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Danio rerio 138613 R-GGA-9020252 https://reactome.org/PathwayBrowser/#/R-GGA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Gallus gallus 138613 R-GGA-9020256 https://reactome.org/PathwayBrowser/#/R-GGA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Gallus gallus 138613 R-HSA-9020252 https://reactome.org/PathwayBrowser/#/R-HSA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 TAS Homo sapiens 138613 R-HSA-9020256 https://reactome.org/PathwayBrowser/#/R-HSA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA TAS Homo sapiens 138613 R-MMU-9020252 https://reactome.org/PathwayBrowser/#/R-MMU-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Mus musculus 138613 R-MMU-9020256 https://reactome.org/PathwayBrowser/#/R-MMU-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Mus musculus 138613 R-RNO-9020252 https://reactome.org/PathwayBrowser/#/R-RNO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Rattus norvegicus 138613 R-RNO-9020256 https://reactome.org/PathwayBrowser/#/R-RNO-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Rattus norvegicus 138613 R-SCE-9020252 https://reactome.org/PathwayBrowser/#/R-SCE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Saccharomyces cerevisiae 138613 R-SPO-9020252 https://reactome.org/PathwayBrowser/#/R-SPO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Schizosaccharomyces pombe 138613 R-SSC-9020252 https://reactome.org/PathwayBrowser/#/R-SSC-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Sus scrofa 138613 R-SSC-9020256 https://reactome.org/PathwayBrowser/#/R-SSC-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Sus scrofa 138613 R-XTR-9020252 https://reactome.org/PathwayBrowser/#/R-XTR-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Xenopus tropicalis 138613 R-XTR-9020256 https://reactome.org/PathwayBrowser/#/R-XTR-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Xenopus tropicalis 138614 R-BTA-9020252 https://reactome.org/PathwayBrowser/#/R-BTA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Bos taurus 138614 R-CEL-9020252 https://reactome.org/PathwayBrowser/#/R-CEL-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Caenorhabditis elegans 138614 R-CFA-9020252 https://reactome.org/PathwayBrowser/#/R-CFA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Canis familiaris 138614 R-DDI-9020252 https://reactome.org/PathwayBrowser/#/R-DDI-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Dictyostelium discoideum 138614 R-DME-9020252 https://reactome.org/PathwayBrowser/#/R-DME-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Drosophila melanogaster 138614 R-DRE-9020252 https://reactome.org/PathwayBrowser/#/R-DRE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Danio rerio 138614 R-GGA-9020252 https://reactome.org/PathwayBrowser/#/R-GGA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Gallus gallus 138614 R-HSA-9020252 https://reactome.org/PathwayBrowser/#/R-HSA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 TAS Homo sapiens 138614 R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138614 R-MMU-9020252 https://reactome.org/PathwayBrowser/#/R-MMU-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Mus musculus 138614 R-RNO-9020252 https://reactome.org/PathwayBrowser/#/R-RNO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Rattus norvegicus 138614 R-SCE-9020252 https://reactome.org/PathwayBrowser/#/R-SCE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Saccharomyces cerevisiae 138614 R-SPO-9020252 https://reactome.org/PathwayBrowser/#/R-SPO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Schizosaccharomyces pombe 138614 R-SSC-9020252 https://reactome.org/PathwayBrowser/#/R-SSC-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Sus scrofa 138614 R-XTR-9020252 https://reactome.org/PathwayBrowser/#/R-XTR-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Xenopus tropicalis 138615 R-BTA-9020270 https://reactome.org/PathwayBrowser/#/R-BTA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Bos taurus 138615 R-CEL-9020270 https://reactome.org/PathwayBrowser/#/R-CEL-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Caenorhabditis elegans 138615 R-CFA-9020270 https://reactome.org/PathwayBrowser/#/R-CFA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Canis familiaris 138615 R-DDI-9020270 https://reactome.org/PathwayBrowser/#/R-DDI-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Dictyostelium discoideum 138615 R-DME-9020270 https://reactome.org/PathwayBrowser/#/R-DME-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Drosophila melanogaster 138615 R-DRE-9020270 https://reactome.org/PathwayBrowser/#/R-DRE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Danio rerio 138615 R-GGA-9020270 https://reactome.org/PathwayBrowser/#/R-GGA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Gallus gallus 138615 R-HSA-9020270 https://reactome.org/PathwayBrowser/#/R-HSA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 TAS Homo sapiens 138615 R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138615 R-MMU-9020270 https://reactome.org/PathwayBrowser/#/R-MMU-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Mus musculus 138615 R-RNO-9020270 https://reactome.org/PathwayBrowser/#/R-RNO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Rattus norvegicus 138615 R-SCE-9020270 https://reactome.org/PathwayBrowser/#/R-SCE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Saccharomyces cerevisiae 138615 R-SPO-9020270 https://reactome.org/PathwayBrowser/#/R-SPO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Schizosaccharomyces pombe 138615 R-SSC-9020270 https://reactome.org/PathwayBrowser/#/R-SSC-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Sus scrofa 138615 R-XTR-9020270 https://reactome.org/PathwayBrowser/#/R-XTR-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Xenopus tropicalis 138616 R-BTA-9020270 https://reactome.org/PathwayBrowser/#/R-BTA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Bos taurus 138616 R-CEL-9020270 https://reactome.org/PathwayBrowser/#/R-CEL-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Caenorhabditis elegans 138616 R-CFA-9020270 https://reactome.org/PathwayBrowser/#/R-CFA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Canis familiaris 138616 R-DDI-9020270 https://reactome.org/PathwayBrowser/#/R-DDI-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Dictyostelium discoideum 138616 R-DME-9020270 https://reactome.org/PathwayBrowser/#/R-DME-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Drosophila melanogaster 138616 R-DRE-9020270 https://reactome.org/PathwayBrowser/#/R-DRE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Danio rerio 138616 R-GGA-9020270 https://reactome.org/PathwayBrowser/#/R-GGA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Gallus gallus 138616 R-HSA-9020270 https://reactome.org/PathwayBrowser/#/R-HSA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 TAS Homo sapiens 138616 R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138616 R-MMU-9020270 https://reactome.org/PathwayBrowser/#/R-MMU-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Mus musculus 138616 R-RNO-9020270 https://reactome.org/PathwayBrowser/#/R-RNO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Rattus norvegicus 138616 R-SCE-9020270 https://reactome.org/PathwayBrowser/#/R-SCE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Saccharomyces cerevisiae 138616 R-SPO-9020270 https://reactome.org/PathwayBrowser/#/R-SPO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Schizosaccharomyces pombe 138616 R-SSC-9020270 https://reactome.org/PathwayBrowser/#/R-SSC-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Sus scrofa 138616 R-XTR-9020270 https://reactome.org/PathwayBrowser/#/R-XTR-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Xenopus tropicalis 138617 R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138617 R-HSA-9024630 https://reactome.org/PathwayBrowser/#/R-HSA-9024630 Hydroperoxy reductase reduces 7(S)-Hp-17(R)-HDHA to AT-RvD5 TAS Homo sapiens 138618 R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138618 R-HSA-9024624 https://reactome.org/PathwayBrowser/#/R-HSA-9024624 Hydroperoxy reductase reduces 4(S)-Hp-17(R)-HDHA to AT-RvD6 TAS Homo sapiens 138640 R-BTA-9020264 https://reactome.org/PathwayBrowser/#/R-BTA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Bos taurus 138640 R-BTA-9020273 https://reactome.org/PathwayBrowser/#/R-BTA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Bos taurus 138640 R-BTA-9020282 https://reactome.org/PathwayBrowser/#/R-BTA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Bos taurus 138640 R-CEL-9020273 https://reactome.org/PathwayBrowser/#/R-CEL-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Caenorhabditis elegans 138640 R-CFA-9020264 https://reactome.org/PathwayBrowser/#/R-CFA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Canis familiaris 138640 R-CFA-9020273 https://reactome.org/PathwayBrowser/#/R-CFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Canis familiaris 138640 R-CFA-9020282 https://reactome.org/PathwayBrowser/#/R-CFA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Canis familiaris 138640 R-DDI-9020264 https://reactome.org/PathwayBrowser/#/R-DDI-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Dictyostelium discoideum 138640 R-DDI-9020282 https://reactome.org/PathwayBrowser/#/R-DDI-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Dictyostelium discoideum 138640 R-DRE-9020264 https://reactome.org/PathwayBrowser/#/R-DRE-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Danio rerio 138640 R-DRE-9020282 https://reactome.org/PathwayBrowser/#/R-DRE-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Danio rerio 138640 R-GGA-9020264 https://reactome.org/PathwayBrowser/#/R-GGA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Gallus gallus 138640 R-GGA-9020273 https://reactome.org/PathwayBrowser/#/R-GGA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Gallus gallus 138640 R-GGA-9020282 https://reactome.org/PathwayBrowser/#/R-GGA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Gallus gallus 138640 R-HSA-9020264 https://reactome.org/PathwayBrowser/#/R-HSA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA TAS Homo sapiens 138640 R-HSA-9020273 https://reactome.org/PathwayBrowser/#/R-HSA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA TAS Homo sapiens 138640 R-HSA-9020282 https://reactome.org/PathwayBrowser/#/R-HSA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA TAS Homo sapiens 138640 R-MMU-9020264 https://reactome.org/PathwayBrowser/#/R-MMU-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Mus musculus 138640 R-MMU-9020273 https://reactome.org/PathwayBrowser/#/R-MMU-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Mus musculus 138640 R-MMU-9020282 https://reactome.org/PathwayBrowser/#/R-MMU-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Mus musculus 138640 R-PFA-9020273 https://reactome.org/PathwayBrowser/#/R-PFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Plasmodium falciparum 138640 R-RNO-9020264 https://reactome.org/PathwayBrowser/#/R-RNO-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Rattus norvegicus 138640 R-RNO-9020273 https://reactome.org/PathwayBrowser/#/R-RNO-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Rattus norvegicus 138640 R-RNO-9020282 https://reactome.org/PathwayBrowser/#/R-RNO-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Rattus norvegicus 138640 R-SSC-9020264 https://reactome.org/PathwayBrowser/#/R-SSC-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Sus scrofa 138640 R-SSC-9020273 https://reactome.org/PathwayBrowser/#/R-SSC-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Sus scrofa 138640 R-SSC-9020282 https://reactome.org/PathwayBrowser/#/R-SSC-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Sus scrofa 138640 R-XTR-9020264 https://reactome.org/PathwayBrowser/#/R-XTR-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Xenopus tropicalis 138640 R-XTR-9020282 https://reactome.org/PathwayBrowser/#/R-XTR-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Xenopus tropicalis 138641 R-BTA-9020264 https://reactome.org/PathwayBrowser/#/R-BTA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Bos taurus 138641 R-BTA-9020277 https://reactome.org/PathwayBrowser/#/R-BTA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Bos taurus 138641 R-CFA-9020264 https://reactome.org/PathwayBrowser/#/R-CFA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Canis familiaris 138641 R-CFA-9020277 https://reactome.org/PathwayBrowser/#/R-CFA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Canis familiaris 138641 R-DDI-9020264 https://reactome.org/PathwayBrowser/#/R-DDI-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Dictyostelium discoideum 138641 R-DDI-9020277 https://reactome.org/PathwayBrowser/#/R-DDI-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Dictyostelium discoideum 138641 R-DRE-9020264 https://reactome.org/PathwayBrowser/#/R-DRE-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Danio rerio 138641 R-DRE-9020277 https://reactome.org/PathwayBrowser/#/R-DRE-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Danio rerio 138641 R-GGA-9020264 https://reactome.org/PathwayBrowser/#/R-GGA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Gallus gallus 138641 R-GGA-9020277 https://reactome.org/PathwayBrowser/#/R-GGA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Gallus gallus 138641 R-HSA-9020249 https://reactome.org/PathwayBrowser/#/R-HSA-9020249 Hydroperoxy reductase reduces 4(S)-Hp-17(S)-HDHA to RvD6 TAS Homo sapiens 138641 R-HSA-9020264 https://reactome.org/PathwayBrowser/#/R-HSA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA TAS Homo sapiens 138641 R-HSA-9020277 https://reactome.org/PathwayBrowser/#/R-HSA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA TAS Homo sapiens 138641 R-MMU-9020264 https://reactome.org/PathwayBrowser/#/R-MMU-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Mus musculus 138641 R-MMU-9020277 https://reactome.org/PathwayBrowser/#/R-MMU-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Mus musculus 138641 R-RNO-9020264 https://reactome.org/PathwayBrowser/#/R-RNO-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Rattus norvegicus 138641 R-RNO-9020277 https://reactome.org/PathwayBrowser/#/R-RNO-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Rattus norvegicus 138641 R-SSC-9020264 https://reactome.org/PathwayBrowser/#/R-SSC-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Sus scrofa 138641 R-SSC-9020277 https://reactome.org/PathwayBrowser/#/R-SSC-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Sus scrofa 138641 R-XTR-9020264 https://reactome.org/PathwayBrowser/#/R-XTR-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Xenopus tropicalis 138641 R-XTR-9020277 https://reactome.org/PathwayBrowser/#/R-XTR-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Xenopus tropicalis 138642 R-BTA-9020255 https://reactome.org/PathwayBrowser/#/R-BTA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Bos taurus 138642 R-BTA-9020282 https://reactome.org/PathwayBrowser/#/R-BTA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Bos taurus 138642 R-CFA-9020255 https://reactome.org/PathwayBrowser/#/R-CFA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Canis familiaris 138642 R-CFA-9020282 https://reactome.org/PathwayBrowser/#/R-CFA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Canis familiaris 138642 R-DDI-9020255 https://reactome.org/PathwayBrowser/#/R-DDI-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Dictyostelium discoideum 138642 R-DDI-9020282 https://reactome.org/PathwayBrowser/#/R-DDI-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Dictyostelium discoideum 138642 R-DRE-9020255 https://reactome.org/PathwayBrowser/#/R-DRE-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Danio rerio 138642 R-DRE-9020282 https://reactome.org/PathwayBrowser/#/R-DRE-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Danio rerio 138642 R-GGA-9020255 https://reactome.org/PathwayBrowser/#/R-GGA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Gallus gallus 138642 R-GGA-9020282 https://reactome.org/PathwayBrowser/#/R-GGA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Gallus gallus 138642 R-HSA-9020255 https://reactome.org/PathwayBrowser/#/R-HSA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA TAS Homo sapiens 138642 R-HSA-9020260 https://reactome.org/PathwayBrowser/#/R-HSA-9020260 Hydroperoxy reducatse reduces 7(S)-Hp-17(S)-HDHA to RvD5 TAS Homo sapiens 138642 R-HSA-9020282 https://reactome.org/PathwayBrowser/#/R-HSA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA TAS Homo sapiens 138642 R-MMU-9020255 https://reactome.org/PathwayBrowser/#/R-MMU-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Mus musculus 138642 R-MMU-9020282 https://reactome.org/PathwayBrowser/#/R-MMU-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Mus musculus 138642 R-RNO-9020255 https://reactome.org/PathwayBrowser/#/R-RNO-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Rattus norvegicus 138642 R-RNO-9020282 https://reactome.org/PathwayBrowser/#/R-RNO-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Rattus norvegicus 138642 R-SSC-9020255 https://reactome.org/PathwayBrowser/#/R-SSC-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Sus scrofa 138642 R-SSC-9020282 https://reactome.org/PathwayBrowser/#/R-SSC-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Sus scrofa 138642 R-XTR-9020255 https://reactome.org/PathwayBrowser/#/R-XTR-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Xenopus tropicalis 138642 R-XTR-9020282 https://reactome.org/PathwayBrowser/#/R-XTR-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Xenopus tropicalis 138643 R-HSA-9020249 https://reactome.org/PathwayBrowser/#/R-HSA-9020249 Hydroperoxy reductase reduces 4(S)-Hp-17(S)-HDHA to RvD6 TAS Homo sapiens 138643 R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138645 R-HSA-9020260 https://reactome.org/PathwayBrowser/#/R-HSA-9020260 Hydroperoxy reducatse reduces 7(S)-Hp-17(S)-HDHA to RvD5 TAS Homo sapiens 138645 R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138646 R-BTA-9020255 https://reactome.org/PathwayBrowser/#/R-BTA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Bos taurus 138646 R-BTA-9020258 https://reactome.org/PathwayBrowser/#/R-BTA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Bos taurus 138646 R-BTA-9026911 https://reactome.org/PathwayBrowser/#/R-BTA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Bos taurus 138646 R-CEL-9020258 https://reactome.org/PathwayBrowser/#/R-CEL-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Caenorhabditis elegans 138646 R-CFA-9020255 https://reactome.org/PathwayBrowser/#/R-CFA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Canis familiaris 138646 R-CFA-9020258 https://reactome.org/PathwayBrowser/#/R-CFA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Canis familiaris 138646 R-CFA-9026911 https://reactome.org/PathwayBrowser/#/R-CFA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Canis familiaris 138646 R-DDI-9020255 https://reactome.org/PathwayBrowser/#/R-DDI-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Dictyostelium discoideum 138646 R-DDI-9020258 https://reactome.org/PathwayBrowser/#/R-DDI-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Dictyostelium discoideum 138646 R-DDI-9026911 https://reactome.org/PathwayBrowser/#/R-DDI-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Dictyostelium discoideum 138646 R-DME-9020258 https://reactome.org/PathwayBrowser/#/R-DME-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Drosophila melanogaster 138646 R-DRE-9020255 https://reactome.org/PathwayBrowser/#/R-DRE-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Danio rerio 138646 R-DRE-9020258 https://reactome.org/PathwayBrowser/#/R-DRE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Danio rerio 138646 R-GGA-9020255 https://reactome.org/PathwayBrowser/#/R-GGA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Gallus gallus 138646 R-GGA-9020258 https://reactome.org/PathwayBrowser/#/R-GGA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Gallus gallus 138646 R-GGA-9026911 https://reactome.org/PathwayBrowser/#/R-GGA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Gallus gallus 138646 R-HSA-9020255 https://reactome.org/PathwayBrowser/#/R-HSA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA TAS Homo sapiens 138646 R-HSA-9020258 https://reactome.org/PathwayBrowser/#/R-HSA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 TAS Homo sapiens 138646 R-HSA-9026911 https://reactome.org/PathwayBrowser/#/R-HSA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 TAS Homo sapiens 138646 R-HSA-9026917 https://reactome.org/PathwayBrowser/#/R-HSA-9026917 Lipoxygenase dehydrogenates 7(S),17(S)-diHp-DHA to 7S(8)-epoxy-17(S)-HDHA TAS Homo sapiens 138646 R-MMU-9020255 https://reactome.org/PathwayBrowser/#/R-MMU-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Mus musculus 138646 R-MMU-9020258 https://reactome.org/PathwayBrowser/#/R-MMU-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Mus musculus 138646 R-MMU-9026911 https://reactome.org/PathwayBrowser/#/R-MMU-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Mus musculus 138646 R-RNO-9020255 https://reactome.org/PathwayBrowser/#/R-RNO-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Rattus norvegicus 138646 R-RNO-9020258 https://reactome.org/PathwayBrowser/#/R-RNO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Rattus norvegicus 138646 R-RNO-9026911 https://reactome.org/PathwayBrowser/#/R-RNO-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Rattus norvegicus 138646 R-SCE-9020258 https://reactome.org/PathwayBrowser/#/R-SCE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Saccharomyces cerevisiae 138646 R-SPO-9020258 https://reactome.org/PathwayBrowser/#/R-SPO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Schizosaccharomyces pombe 138646 R-SSC-9020255 https://reactome.org/PathwayBrowser/#/R-SSC-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Sus scrofa 138646 R-SSC-9020258 https://reactome.org/PathwayBrowser/#/R-SSC-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Sus scrofa 138646 R-SSC-9026911 https://reactome.org/PathwayBrowser/#/R-SSC-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Sus scrofa 138646 R-XTR-9020255 https://reactome.org/PathwayBrowser/#/R-XTR-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Xenopus tropicalis 138646 R-XTR-9020258 https://reactome.org/PathwayBrowser/#/R-XTR-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Xenopus tropicalis 138646 R-XTR-9026911 https://reactome.org/PathwayBrowser/#/R-XTR-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Xenopus tropicalis 138647 R-BTA-9020253 https://reactome.org/PathwayBrowser/#/R-BTA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Bos taurus 138647 R-BTA-9020277 https://reactome.org/PathwayBrowser/#/R-BTA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Bos taurus 138647 R-CEL-9020253 https://reactome.org/PathwayBrowser/#/R-CEL-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Caenorhabditis elegans 138647 R-CFA-9020253 https://reactome.org/PathwayBrowser/#/R-CFA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Canis familiaris 138647 R-CFA-9020277 https://reactome.org/PathwayBrowser/#/R-CFA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Canis familiaris 138647 R-DDI-9020253 https://reactome.org/PathwayBrowser/#/R-DDI-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Dictyostelium discoideum 138647 R-DDI-9020277 https://reactome.org/PathwayBrowser/#/R-DDI-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Dictyostelium discoideum 138647 R-DME-9020253 https://reactome.org/PathwayBrowser/#/R-DME-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Drosophila melanogaster 138647 R-DRE-9020253 https://reactome.org/PathwayBrowser/#/R-DRE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Danio rerio 138647 R-DRE-9020277 https://reactome.org/PathwayBrowser/#/R-DRE-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Danio rerio 138647 R-GGA-9020253 https://reactome.org/PathwayBrowser/#/R-GGA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Gallus gallus 138647 R-GGA-9020277 https://reactome.org/PathwayBrowser/#/R-GGA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Gallus gallus 138647 R-HSA-9020253 https://reactome.org/PathwayBrowser/#/R-HSA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 TAS Homo sapiens 138647 R-HSA-9020277 https://reactome.org/PathwayBrowser/#/R-HSA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA TAS Homo sapiens 138647 R-MMU-9020253 https://reactome.org/PathwayBrowser/#/R-MMU-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Mus musculus 138647 R-MMU-9020277 https://reactome.org/PathwayBrowser/#/R-MMU-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Mus musculus 138647 R-RNO-9020253 https://reactome.org/PathwayBrowser/#/R-RNO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Rattus norvegicus 138647 R-RNO-9020277 https://reactome.org/PathwayBrowser/#/R-RNO-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Rattus norvegicus 138647 R-SCE-9020253 https://reactome.org/PathwayBrowser/#/R-SCE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Saccharomyces cerevisiae 138647 R-SPO-9020253 https://reactome.org/PathwayBrowser/#/R-SPO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Schizosaccharomyces pombe 138647 R-SSC-9020253 https://reactome.org/PathwayBrowser/#/R-SSC-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Sus scrofa 138647 R-SSC-9020277 https://reactome.org/PathwayBrowser/#/R-SSC-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Sus scrofa 138647 R-XTR-9020253 https://reactome.org/PathwayBrowser/#/R-XTR-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Xenopus tropicalis 138647 R-XTR-9020277 https://reactome.org/PathwayBrowser/#/R-XTR-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Xenopus tropicalis 138648 R-BTA-9020253 https://reactome.org/PathwayBrowser/#/R-BTA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Bos taurus 138648 R-CEL-9020253 https://reactome.org/PathwayBrowser/#/R-CEL-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Caenorhabditis elegans 138648 R-CFA-9020253 https://reactome.org/PathwayBrowser/#/R-CFA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Canis familiaris 138648 R-DDI-9020253 https://reactome.org/PathwayBrowser/#/R-DDI-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Dictyostelium discoideum 138648 R-DME-9020253 https://reactome.org/PathwayBrowser/#/R-DME-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Drosophila melanogaster 138648 R-DRE-9020253 https://reactome.org/PathwayBrowser/#/R-DRE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Danio rerio 138648 R-GGA-9020253 https://reactome.org/PathwayBrowser/#/R-GGA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Gallus gallus 138648 R-HSA-9020253 https://reactome.org/PathwayBrowser/#/R-HSA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 TAS Homo sapiens 138648 R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138648 R-MMU-9020253 https://reactome.org/PathwayBrowser/#/R-MMU-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Mus musculus 138648 R-RNO-9020253 https://reactome.org/PathwayBrowser/#/R-RNO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Rattus norvegicus 138648 R-SCE-9020253 https://reactome.org/PathwayBrowser/#/R-SCE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Saccharomyces cerevisiae 138648 R-SPO-9020253 https://reactome.org/PathwayBrowser/#/R-SPO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Schizosaccharomyces pombe 138648 R-SSC-9020253 https://reactome.org/PathwayBrowser/#/R-SSC-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Sus scrofa 138648 R-XTR-9020253 https://reactome.org/PathwayBrowser/#/R-XTR-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Xenopus tropicalis 138649 R-BTA-9020253 https://reactome.org/PathwayBrowser/#/R-BTA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Bos taurus 138649 R-CEL-9020253 https://reactome.org/PathwayBrowser/#/R-CEL-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Caenorhabditis elegans 138649 R-CFA-9020253 https://reactome.org/PathwayBrowser/#/R-CFA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Canis familiaris 138649 R-DDI-9020253 https://reactome.org/PathwayBrowser/#/R-DDI-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Dictyostelium discoideum 138649 R-DME-9020253 https://reactome.org/PathwayBrowser/#/R-DME-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Drosophila melanogaster 138649 R-DRE-9020253 https://reactome.org/PathwayBrowser/#/R-DRE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Danio rerio 138649 R-GGA-9020253 https://reactome.org/PathwayBrowser/#/R-GGA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Gallus gallus 138649 R-HSA-9020253 https://reactome.org/PathwayBrowser/#/R-HSA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 TAS Homo sapiens 138649 R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138649 R-MMU-9020253 https://reactome.org/PathwayBrowser/#/R-MMU-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Mus musculus 138649 R-RNO-9020253 https://reactome.org/PathwayBrowser/#/R-RNO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Rattus norvegicus 138649 R-SCE-9020253 https://reactome.org/PathwayBrowser/#/R-SCE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Saccharomyces cerevisiae 138649 R-SPO-9020253 https://reactome.org/PathwayBrowser/#/R-SPO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Schizosaccharomyces pombe 138649 R-SSC-9020253 https://reactome.org/PathwayBrowser/#/R-SSC-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Sus scrofa 138649 R-XTR-9020253 https://reactome.org/PathwayBrowser/#/R-XTR-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Xenopus tropicalis 138653 R-BTA-9024872 https://reactome.org/PathwayBrowser/#/R-BTA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Bos taurus 138653 R-CFA-9024872 https://reactome.org/PathwayBrowser/#/R-CFA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Canis familiaris 138653 R-DDI-9024872 https://reactome.org/PathwayBrowser/#/R-DDI-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Dictyostelium discoideum 138653 R-DRE-9024872 https://reactome.org/PathwayBrowser/#/R-DRE-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Danio rerio 138653 R-HSA-9024872 https://reactome.org/PathwayBrowser/#/R-HSA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX TAS Homo sapiens 138653 R-HSA-9031807 https://reactome.org/PathwayBrowser/#/R-HSA-9031807 Protectins translocate from cytosol to extracellular region TAS Homo sapiens 138653 R-MMU-9024872 https://reactome.org/PathwayBrowser/#/R-MMU-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Mus musculus 138653 R-RNO-9024872 https://reactome.org/PathwayBrowser/#/R-RNO-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Rattus norvegicus 138653 R-SSC-9024872 https://reactome.org/PathwayBrowser/#/R-SSC-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Sus scrofa 138655 R-BTA-9024890 https://reactome.org/PathwayBrowser/#/R-BTA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Bos taurus 138655 R-BTA-9037761 https://reactome.org/PathwayBrowser/#/R-BTA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Bos taurus 138655 R-CEL-9024890 https://reactome.org/PathwayBrowser/#/R-CEL-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Caenorhabditis elegans 138655 R-CFA-9024890 https://reactome.org/PathwayBrowser/#/R-CFA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Canis familiaris 138655 R-DDI-9024890 https://reactome.org/PathwayBrowser/#/R-DDI-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Dictyostelium discoideum 138655 R-DME-9024890 https://reactome.org/PathwayBrowser/#/R-DME-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Drosophila melanogaster 138655 R-DRE-9024890 https://reactome.org/PathwayBrowser/#/R-DRE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Danio rerio 138655 R-DRE-9037761 https://reactome.org/PathwayBrowser/#/R-DRE-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Danio rerio 138655 R-GGA-9024890 https://reactome.org/PathwayBrowser/#/R-GGA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Gallus gallus 138655 R-GGA-9037761 https://reactome.org/PathwayBrowser/#/R-GGA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Gallus gallus 138655 R-HSA-9024890 https://reactome.org/PathwayBrowser/#/R-HSA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 TAS Homo sapiens 138655 R-HSA-9031807 https://reactome.org/PathwayBrowser/#/R-HSA-9031807 Protectins translocate from cytosol to extracellular region TAS Homo sapiens 138655 R-HSA-9037761 https://reactome.org/PathwayBrowser/#/R-HSA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 TAS Homo sapiens 138655 R-MMU-9024890 https://reactome.org/PathwayBrowser/#/R-MMU-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Mus musculus 138655 R-MMU-9037761 https://reactome.org/PathwayBrowser/#/R-MMU-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Mus musculus 138655 R-RNO-9024890 https://reactome.org/PathwayBrowser/#/R-RNO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Rattus norvegicus 138655 R-RNO-9037761 https://reactome.org/PathwayBrowser/#/R-RNO-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Rattus norvegicus 138655 R-SCE-9024890 https://reactome.org/PathwayBrowser/#/R-SCE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Saccharomyces cerevisiae 138655 R-SPO-9024890 https://reactome.org/PathwayBrowser/#/R-SPO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Schizosaccharomyces pombe 138655 R-SSC-9024890 https://reactome.org/PathwayBrowser/#/R-SSC-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Sus scrofa 138655 R-SSC-9037761 https://reactome.org/PathwayBrowser/#/R-SSC-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Sus scrofa 138655 R-XTR-9024890 https://reactome.org/PathwayBrowser/#/R-XTR-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Xenopus tropicalis 138673 R-BTA-9025152 https://reactome.org/PathwayBrowser/#/R-BTA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Bos taurus 138673 R-CFA-9025152 https://reactome.org/PathwayBrowser/#/R-CFA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Canis familiaris 138673 R-DDI-9025152 https://reactome.org/PathwayBrowser/#/R-DDI-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Dictyostelium discoideum 138673 R-DRE-9025152 https://reactome.org/PathwayBrowser/#/R-DRE-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Danio rerio 138673 R-HSA-9025152 https://reactome.org/PathwayBrowser/#/R-HSA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 TAS Homo sapiens 138673 R-HSA-9031884 https://reactome.org/PathwayBrowser/#/R-HSA-9031884 DPAn-6 SPMs translocate from cytosol to extracellular region TAS Homo sapiens 138673 R-MMU-9025152 https://reactome.org/PathwayBrowser/#/R-MMU-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Mus musculus 138673 R-RNO-9025152 https://reactome.org/PathwayBrowser/#/R-RNO-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Rattus norvegicus 138673 R-SSC-9025152 https://reactome.org/PathwayBrowser/#/R-SSC-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Sus scrofa 138674 R-BTA-9025152 https://reactome.org/PathwayBrowser/#/R-BTA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Bos taurus 138674 R-CFA-9025152 https://reactome.org/PathwayBrowser/#/R-CFA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Canis familiaris 138674 R-DDI-9025152 https://reactome.org/PathwayBrowser/#/R-DDI-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Dictyostelium discoideum 138674 R-DRE-9025152 https://reactome.org/PathwayBrowser/#/R-DRE-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Danio rerio 138674 R-HSA-9025152 https://reactome.org/PathwayBrowser/#/R-HSA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 TAS Homo sapiens 138674 R-HSA-9031884 https://reactome.org/PathwayBrowser/#/R-HSA-9031884 DPAn-6 SPMs translocate from cytosol to extracellular region TAS Homo sapiens 138674 R-MMU-9025152 https://reactome.org/PathwayBrowser/#/R-MMU-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Mus musculus 138674 R-RNO-9025152 https://reactome.org/PathwayBrowser/#/R-RNO-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Rattus norvegicus 138674 R-SSC-9025152 https://reactome.org/PathwayBrowser/#/R-SSC-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Sus scrofa 138881 R-BTA-70333 https://reactome.org/PathwayBrowser/#/R-BTA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Bos taurus 138881 R-BTA-70342 https://reactome.org/PathwayBrowser/#/R-BTA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Bos taurus 138881 R-CEL-70342 https://reactome.org/PathwayBrowser/#/R-CEL-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Caenorhabditis elegans 138881 R-CFA-70342 https://reactome.org/PathwayBrowser/#/R-CFA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Canis familiaris 138881 R-DDI-70333 https://reactome.org/PathwayBrowser/#/R-DDI-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Dictyostelium discoideum 138881 R-DDI-70342 https://reactome.org/PathwayBrowser/#/R-DDI-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Dictyostelium discoideum 138881 R-DME-70333 https://reactome.org/PathwayBrowser/#/R-DME-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Drosophila melanogaster 138881 R-DME-70342 https://reactome.org/PathwayBrowser/#/R-DME-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Drosophila melanogaster 138881 R-DRE-70342 https://reactome.org/PathwayBrowser/#/R-DRE-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Danio rerio 138881 R-GGA-70333 https://reactome.org/PathwayBrowser/#/R-GGA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Gallus gallus 138881 R-GGA-70342 https://reactome.org/PathwayBrowser/#/R-GGA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Gallus gallus 138881 R-HSA-70333 https://reactome.org/PathwayBrowser/#/R-HSA-70333 KHK dimer phosphorylates Fru to Fru 1-P TAS Homo sapiens 138881 R-HSA-70342 https://reactome.org/PathwayBrowser/#/R-HSA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP TAS Homo sapiens 138881 R-MMU-70333 https://reactome.org/PathwayBrowser/#/R-MMU-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Mus musculus 138881 R-MMU-70342 https://reactome.org/PathwayBrowser/#/R-MMU-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Mus musculus 138881 R-PFA-70342 https://reactome.org/PathwayBrowser/#/R-PFA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Plasmodium falciparum 138881 R-RNO-70333 https://reactome.org/PathwayBrowser/#/R-RNO-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Rattus norvegicus 138881 R-RNO-70342 https://reactome.org/PathwayBrowser/#/R-RNO-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Rattus norvegicus 138881 R-SSC-70333 https://reactome.org/PathwayBrowser/#/R-SSC-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Sus scrofa 138881 R-SSC-70342 https://reactome.org/PathwayBrowser/#/R-SSC-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Sus scrofa 138881 R-XTR-70342 https://reactome.org/PathwayBrowser/#/R-XTR-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Xenopus tropicalis 139048 R-BTA-428185 https://reactome.org/PathwayBrowser/#/R-BTA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Bos taurus 139048 R-BTA-428259 https://reactome.org/PathwayBrowser/#/R-BTA-428259 DEGS1 dehydrogenates dihydroceramide IEA Bos taurus 139048 R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 139048 R-CEL-428185 https://reactome.org/PathwayBrowser/#/R-CEL-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Caenorhabditis elegans 139048 R-CEL-428259 https://reactome.org/PathwayBrowser/#/R-CEL-428259 DEGS1 dehydrogenates dihydroceramide IEA Caenorhabditis elegans 139048 R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 139048 R-CFA-428185 https://reactome.org/PathwayBrowser/#/R-CFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Canis familiaris 139048 R-CFA-428259 https://reactome.org/PathwayBrowser/#/R-CFA-428259 DEGS1 dehydrogenates dihydroceramide IEA Canis familiaris 139048 R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 139048 R-DDI-428185 https://reactome.org/PathwayBrowser/#/R-DDI-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Dictyostelium discoideum 139048 R-DDI-428259 https://reactome.org/PathwayBrowser/#/R-DDI-428259 DEGS1 dehydrogenates dihydroceramide IEA Dictyostelium discoideum 139048 R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 139048 R-DME-428185 https://reactome.org/PathwayBrowser/#/R-DME-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Drosophila melanogaster 139048 R-DME-428259 https://reactome.org/PathwayBrowser/#/R-DME-428259 DEGS1 dehydrogenates dihydroceramide IEA Drosophila melanogaster 139048 R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 139048 R-DRE-428185 https://reactome.org/PathwayBrowser/#/R-DRE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Danio rerio 139048 R-DRE-428259 https://reactome.org/PathwayBrowser/#/R-DRE-428259 DEGS1 dehydrogenates dihydroceramide IEA Danio rerio 139048 R-GGA-428185 https://reactome.org/PathwayBrowser/#/R-GGA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Gallus gallus 139048 R-GGA-428259 https://reactome.org/PathwayBrowser/#/R-GGA-428259 DEGS1 dehydrogenates dihydroceramide IEA Gallus gallus 139048 R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 139048 R-GGA-433592 https://reactome.org/PathwayBrowser/#/R-GGA-433592 sphinganine + stearyl-CoA => dihydroceramide + CoASH IEA Gallus gallus 139048 R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 139048 R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 139048 R-HSA-428185 https://reactome.org/PathwayBrowser/#/R-HSA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid TAS Homo sapiens 139048 R-HSA-428259 https://reactome.org/PathwayBrowser/#/R-HSA-428259 DEGS1 dehydrogenates dihydroceramide TAS Homo sapiens 139048 R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 139048 R-MMU-428185 https://reactome.org/PathwayBrowser/#/R-MMU-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Mus musculus 139048 R-MMU-428259 https://reactome.org/PathwayBrowser/#/R-MMU-428259 DEGS1 dehydrogenates dihydroceramide IEA Mus musculus 139048 R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 139048 R-PFA-428185 https://reactome.org/PathwayBrowser/#/R-PFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Plasmodium falciparum 139048 R-RNO-428185 https://reactome.org/PathwayBrowser/#/R-RNO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Rattus norvegicus 139048 R-RNO-428259 https://reactome.org/PathwayBrowser/#/R-RNO-428259 DEGS1 dehydrogenates dihydroceramide IEA Rattus norvegicus 139048 R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 139048 R-SCE-428185 https://reactome.org/PathwayBrowser/#/R-SCE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Saccharomyces cerevisiae 139048 R-SPO-428185 https://reactome.org/PathwayBrowser/#/R-SPO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Schizosaccharomyces pombe 139048 R-SPO-428259 https://reactome.org/PathwayBrowser/#/R-SPO-428259 DEGS1 dehydrogenates dihydroceramide IEA Schizosaccharomyces pombe 139048 R-SPO-428260 https://reactome.org/PathwayBrowser/#/R-SPO-428260 DEGS2 oxygenates dihydroceramide IEA Schizosaccharomyces pombe 139048 R-SSC-428185 https://reactome.org/PathwayBrowser/#/R-SSC-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Sus scrofa 139048 R-SSC-428259 https://reactome.org/PathwayBrowser/#/R-SSC-428259 DEGS1 dehydrogenates dihydroceramide IEA Sus scrofa 139048 R-SSC-428260 https://reactome.org/PathwayBrowser/#/R-SSC-428260 DEGS2 oxygenates dihydroceramide IEA Sus scrofa 139048 R-XTR-428185 https://reactome.org/PathwayBrowser/#/R-XTR-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Xenopus tropicalis 139048 R-XTR-428259 https://reactome.org/PathwayBrowser/#/R-XTR-428259 DEGS1 dehydrogenates dihydroceramide IEA Xenopus tropicalis 139048 R-XTR-428260 https://reactome.org/PathwayBrowser/#/R-XTR-428260 DEGS2 oxygenates dihydroceramide IEA Xenopus tropicalis 139051 R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 139051 R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 139051 R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 139051 R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 139051 R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 139051 R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 139051 R-GGA-433578 https://reactome.org/PathwayBrowser/#/R-GGA-433578 phytoceramide + H2O => stearate + phytosphingosine IEA Gallus gallus 139051 R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 139051 R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 139051 R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 139051 R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 139051 R-SPO-428260 https://reactome.org/PathwayBrowser/#/R-SPO-428260 DEGS2 oxygenates dihydroceramide IEA Schizosaccharomyces pombe 139051 R-SSC-428260 https://reactome.org/PathwayBrowser/#/R-SSC-428260 DEGS2 oxygenates dihydroceramide IEA Sus scrofa 139051 R-XTR-428260 https://reactome.org/PathwayBrowser/#/R-XTR-428260 DEGS2 oxygenates dihydroceramide IEA Xenopus tropicalis 139150 R-BTA-9840884 https://reactome.org/PathwayBrowser/#/R-BTA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Bos taurus 139150 R-CEL-9840884 https://reactome.org/PathwayBrowser/#/R-CEL-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Caenorhabditis elegans 139150 R-CFA-9840884 https://reactome.org/PathwayBrowser/#/R-CFA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Canis familiaris 139150 R-HSA-9840884 https://reactome.org/PathwayBrowser/#/R-HSA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 TAS Homo sapiens 139150 R-MMU-9840884 https://reactome.org/PathwayBrowser/#/R-MMU-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Mus musculus 139150 R-RNO-9840884 https://reactome.org/PathwayBrowser/#/R-RNO-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Rattus norvegicus 139150 R-SSC-9840884 https://reactome.org/PathwayBrowser/#/R-SSC-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Sus scrofa 139350 R-BTA-9033949 https://reactome.org/PathwayBrowser/#/R-BTA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Bos taurus 139350 R-BTA-9603984 https://reactome.org/PathwayBrowser/#/R-BTA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Bos taurus 139350 R-BTA-9605600 https://reactome.org/PathwayBrowser/#/R-BTA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Bos taurus 139350 R-CEL-9033949 https://reactome.org/PathwayBrowser/#/R-CEL-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Caenorhabditis elegans 139350 R-CEL-9603984 https://reactome.org/PathwayBrowser/#/R-CEL-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Caenorhabditis elegans 139350 R-CFA-9603984 https://reactome.org/PathwayBrowser/#/R-CFA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Canis familiaris 139350 R-CFA-9605600 https://reactome.org/PathwayBrowser/#/R-CFA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Canis familiaris 139350 R-DDI-9603984 https://reactome.org/PathwayBrowser/#/R-DDI-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Dictyostelium discoideum 139350 R-DME-9603984 https://reactome.org/PathwayBrowser/#/R-DME-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Drosophila melanogaster 139350 R-DRE-9603984 https://reactome.org/PathwayBrowser/#/R-DRE-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Danio rerio 139350 R-DRE-9605600 https://reactome.org/PathwayBrowser/#/R-DRE-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Danio rerio 139350 R-GGA-9603984 https://reactome.org/PathwayBrowser/#/R-GGA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Gallus gallus 139350 R-GGA-9605600 https://reactome.org/PathwayBrowser/#/R-GGA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Gallus gallus 139350 R-HSA-9033949 https://reactome.org/PathwayBrowser/#/R-HSA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC TAS Homo sapiens 139350 R-HSA-9603984 https://reactome.org/PathwayBrowser/#/R-HSA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX TAS Homo sapiens 139350 R-HSA-9605600 https://reactome.org/PathwayBrowser/#/R-HSA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG TAS Homo sapiens 139350 R-MMU-9033949 https://reactome.org/PathwayBrowser/#/R-MMU-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Mus musculus 139350 R-MMU-9603984 https://reactome.org/PathwayBrowser/#/R-MMU-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Mus musculus 139350 R-MMU-9605600 https://reactome.org/PathwayBrowser/#/R-MMU-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Mus musculus 139350 R-RNO-9033949 https://reactome.org/PathwayBrowser/#/R-RNO-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Rattus norvegicus 139350 R-RNO-9603984 https://reactome.org/PathwayBrowser/#/R-RNO-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Rattus norvegicus 139350 R-RNO-9605600 https://reactome.org/PathwayBrowser/#/R-RNO-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Rattus norvegicus 139350 R-SSC-9033949 https://reactome.org/PathwayBrowser/#/R-SSC-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Sus scrofa 139350 R-SSC-9603984 https://reactome.org/PathwayBrowser/#/R-SSC-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Sus scrofa 139350 R-SSC-9605600 https://reactome.org/PathwayBrowser/#/R-SSC-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Sus scrofa 139350 R-XTR-9033949 https://reactome.org/PathwayBrowser/#/R-XTR-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Xenopus tropicalis 139350 R-XTR-9603984 https://reactome.org/PathwayBrowser/#/R-XTR-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Xenopus tropicalis 139350 R-XTR-9605600 https://reactome.org/PathwayBrowser/#/R-XTR-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Xenopus tropicalis 139351 R-BTA-9033949 https://reactome.org/PathwayBrowser/#/R-BTA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Bos taurus 139351 R-BTA-9033959 https://reactome.org/PathwayBrowser/#/R-BTA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Bos taurus 139351 R-BTA-9033961 https://reactome.org/PathwayBrowser/#/R-BTA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Bos taurus 139351 R-CEL-9033949 https://reactome.org/PathwayBrowser/#/R-CEL-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Caenorhabditis elegans 139351 R-CFA-9033959 https://reactome.org/PathwayBrowser/#/R-CFA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Canis familiaris 139351 R-CFA-9033961 https://reactome.org/PathwayBrowser/#/R-CFA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Canis familiaris 139351 R-DRE-9033959 https://reactome.org/PathwayBrowser/#/R-DRE-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Danio rerio 139351 R-DRE-9033961 https://reactome.org/PathwayBrowser/#/R-DRE-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Danio rerio 139351 R-HSA-9033949 https://reactome.org/PathwayBrowser/#/R-HSA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC TAS Homo sapiens 139351 R-HSA-9033959 https://reactome.org/PathwayBrowser/#/R-HSA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC TAS Homo sapiens 139351 R-HSA-9033961 https://reactome.org/PathwayBrowser/#/R-HSA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC TAS Homo sapiens 139351 R-MMU-9033949 https://reactome.org/PathwayBrowser/#/R-MMU-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Mus musculus 139351 R-MMU-9033959 https://reactome.org/PathwayBrowser/#/R-MMU-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Mus musculus 139351 R-MMU-9033961 https://reactome.org/PathwayBrowser/#/R-MMU-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Mus musculus 139351 R-RNO-9033949 https://reactome.org/PathwayBrowser/#/R-RNO-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Rattus norvegicus 139351 R-RNO-9033959 https://reactome.org/PathwayBrowser/#/R-RNO-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Rattus norvegicus 139351 R-RNO-9033961 https://reactome.org/PathwayBrowser/#/R-RNO-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Rattus norvegicus 139351 R-SSC-9033949 https://reactome.org/PathwayBrowser/#/R-SSC-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Sus scrofa 139351 R-XTR-9033949 https://reactome.org/PathwayBrowser/#/R-XTR-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Xenopus tropicalis 139351 R-XTR-9033959 https://reactome.org/PathwayBrowser/#/R-XTR-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Xenopus tropicalis 139351 R-XTR-9033961 https://reactome.org/PathwayBrowser/#/R-XTR-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Xenopus tropicalis 139352 R-BTA-9033959 https://reactome.org/PathwayBrowser/#/R-BTA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Bos taurus 139352 R-CFA-9033959 https://reactome.org/PathwayBrowser/#/R-CFA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Canis familiaris 139352 R-DRE-9033959 https://reactome.org/PathwayBrowser/#/R-DRE-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Danio rerio 139352 R-HSA-9033959 https://reactome.org/PathwayBrowser/#/R-HSA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC TAS Homo sapiens 139352 R-MMU-9033959 https://reactome.org/PathwayBrowser/#/R-MMU-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Mus musculus 139352 R-RNO-9033959 https://reactome.org/PathwayBrowser/#/R-RNO-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Rattus norvegicus 139352 R-XTR-9033959 https://reactome.org/PathwayBrowser/#/R-XTR-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Xenopus tropicalis 139353 R-BTA-9033961 https://reactome.org/PathwayBrowser/#/R-BTA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Bos taurus 139353 R-CFA-9033961 https://reactome.org/PathwayBrowser/#/R-CFA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Canis familiaris 139353 R-DRE-9033961 https://reactome.org/PathwayBrowser/#/R-DRE-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Danio rerio 139353 R-HSA-9033961 https://reactome.org/PathwayBrowser/#/R-HSA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC TAS Homo sapiens 139353 R-MMU-9033961 https://reactome.org/PathwayBrowser/#/R-MMU-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Mus musculus 139353 R-RNO-9033961 https://reactome.org/PathwayBrowser/#/R-RNO-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Rattus norvegicus 139353 R-XTR-9033961 https://reactome.org/PathwayBrowser/#/R-XTR-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Xenopus tropicalis 140162 R-BTA-9036987 https://reactome.org/PathwayBrowser/#/R-BTA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Bos taurus 140162 R-BTA-9603986 https://reactome.org/PathwayBrowser/#/R-BTA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Bos taurus 140162 R-BTA-9603987 https://reactome.org/PathwayBrowser/#/R-BTA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Bos taurus 140162 R-BTA-9603989 https://reactome.org/PathwayBrowser/#/R-BTA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Bos taurus 140162 R-CEL-9036987 https://reactome.org/PathwayBrowser/#/R-CEL-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Caenorhabditis elegans 140162 R-CEL-9603986 https://reactome.org/PathwayBrowser/#/R-CEL-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Caenorhabditis elegans 140162 R-CEL-9603989 https://reactome.org/PathwayBrowser/#/R-CEL-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Caenorhabditis elegans 140162 R-CFA-9036987 https://reactome.org/PathwayBrowser/#/R-CFA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Canis familiaris 140162 R-CFA-9603986 https://reactome.org/PathwayBrowser/#/R-CFA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Canis familiaris 140162 R-CFA-9603987 https://reactome.org/PathwayBrowser/#/R-CFA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Canis familiaris 140162 R-CFA-9603989 https://reactome.org/PathwayBrowser/#/R-CFA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Canis familiaris 140162 R-DDI-9603986 https://reactome.org/PathwayBrowser/#/R-DDI-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Dictyostelium discoideum 140162 R-DME-9603986 https://reactome.org/PathwayBrowser/#/R-DME-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Drosophila melanogaster 140162 R-DME-9603989 https://reactome.org/PathwayBrowser/#/R-DME-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Drosophila melanogaster 140162 R-DRE-9603989 https://reactome.org/PathwayBrowser/#/R-DRE-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Danio rerio 140162 R-GGA-9603987 https://reactome.org/PathwayBrowser/#/R-GGA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Gallus gallus 140162 R-GGA-9603989 https://reactome.org/PathwayBrowser/#/R-GGA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Gallus gallus 140162 R-HSA-9036987 https://reactome.org/PathwayBrowser/#/R-HSA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec TAS Homo sapiens 140162 R-HSA-9603986 https://reactome.org/PathwayBrowser/#/R-HSA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA TAS Homo sapiens 140162 R-HSA-9603987 https://reactome.org/PathwayBrowser/#/R-HSA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG TAS Homo sapiens 140162 R-HSA-9603989 https://reactome.org/PathwayBrowser/#/R-HSA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain TAS Homo sapiens 140162 R-MMU-9036987 https://reactome.org/PathwayBrowser/#/R-MMU-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Mus musculus 140162 R-MMU-9603987 https://reactome.org/PathwayBrowser/#/R-MMU-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Mus musculus 140162 R-MMU-9603989 https://reactome.org/PathwayBrowser/#/R-MMU-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Mus musculus 140162 R-RNO-9036987 https://reactome.org/PathwayBrowser/#/R-RNO-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Rattus norvegicus 140162 R-RNO-9603987 https://reactome.org/PathwayBrowser/#/R-RNO-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Rattus norvegicus 140162 R-RNO-9603989 https://reactome.org/PathwayBrowser/#/R-RNO-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Rattus norvegicus 140162 R-SSC-9036987 https://reactome.org/PathwayBrowser/#/R-SSC-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Sus scrofa 140162 R-SSC-9603986 https://reactome.org/PathwayBrowser/#/R-SSC-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Sus scrofa 140162 R-SSC-9603987 https://reactome.org/PathwayBrowser/#/R-SSC-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Sus scrofa 140162 R-SSC-9603989 https://reactome.org/PathwayBrowser/#/R-SSC-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Sus scrofa 140162 R-XTR-9036987 https://reactome.org/PathwayBrowser/#/R-XTR-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Xenopus tropicalis 140162 R-XTR-9603986 https://reactome.org/PathwayBrowser/#/R-XTR-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Xenopus tropicalis 140162 R-XTR-9603987 https://reactome.org/PathwayBrowser/#/R-XTR-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Xenopus tropicalis 140162 R-XTR-9603989 https://reactome.org/PathwayBrowser/#/R-XTR-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Xenopus tropicalis 140180 R-BTA-9034042 https://reactome.org/PathwayBrowser/#/R-BTA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Bos taurus 140180 R-BTA-9034053 https://reactome.org/PathwayBrowser/#/R-BTA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Bos taurus 140180 R-BTA-9036987 https://reactome.org/PathwayBrowser/#/R-BTA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Bos taurus 140180 R-CEL-9036987 https://reactome.org/PathwayBrowser/#/R-CEL-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Caenorhabditis elegans 140180 R-CFA-9034042 https://reactome.org/PathwayBrowser/#/R-CFA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Canis familiaris 140180 R-CFA-9034053 https://reactome.org/PathwayBrowser/#/R-CFA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Canis familiaris 140180 R-CFA-9036987 https://reactome.org/PathwayBrowser/#/R-CFA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Canis familiaris 140180 R-DRE-9034042 https://reactome.org/PathwayBrowser/#/R-DRE-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Danio rerio 140180 R-DRE-9034053 https://reactome.org/PathwayBrowser/#/R-DRE-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Danio rerio 140180 R-HSA-9034042 https://reactome.org/PathwayBrowser/#/R-HSA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec TAS Homo sapiens 140180 R-HSA-9034053 https://reactome.org/PathwayBrowser/#/R-HSA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen TAS Homo sapiens 140180 R-HSA-9036987 https://reactome.org/PathwayBrowser/#/R-HSA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec TAS Homo sapiens 140180 R-HSA-9037612 https://reactome.org/PathwayBrowser/#/R-HSA-9037612 H antigen-sec translocates from Golgi lumen to extracellular region TAS Homo sapiens 140180 R-MMU-9034042 https://reactome.org/PathwayBrowser/#/R-MMU-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Mus musculus 140180 R-MMU-9034053 https://reactome.org/PathwayBrowser/#/R-MMU-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Mus musculus 140180 R-MMU-9036987 https://reactome.org/PathwayBrowser/#/R-MMU-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Mus musculus 140180 R-RNO-9034042 https://reactome.org/PathwayBrowser/#/R-RNO-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Rattus norvegicus 140180 R-RNO-9034053 https://reactome.org/PathwayBrowser/#/R-RNO-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Rattus norvegicus 140180 R-RNO-9036987 https://reactome.org/PathwayBrowser/#/R-RNO-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Rattus norvegicus 140180 R-SSC-9036987 https://reactome.org/PathwayBrowser/#/R-SSC-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Sus scrofa 140180 R-XTR-9034042 https://reactome.org/PathwayBrowser/#/R-XTR-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Xenopus tropicalis 140180 R-XTR-9034053 https://reactome.org/PathwayBrowser/#/R-XTR-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Xenopus tropicalis 140180 R-XTR-9036987 https://reactome.org/PathwayBrowser/#/R-XTR-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Xenopus tropicalis 140186 R-BTA-9034042 https://reactome.org/PathwayBrowser/#/R-BTA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Bos taurus 140186 R-CFA-9034042 https://reactome.org/PathwayBrowser/#/R-CFA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Canis familiaris 140186 R-DRE-9034042 https://reactome.org/PathwayBrowser/#/R-DRE-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Danio rerio 140186 R-HSA-9034042 https://reactome.org/PathwayBrowser/#/R-HSA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec TAS Homo sapiens 140186 R-MMU-9034042 https://reactome.org/PathwayBrowser/#/R-MMU-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Mus musculus 140186 R-RNO-9034042 https://reactome.org/PathwayBrowser/#/R-RNO-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Rattus norvegicus 140186 R-XTR-9034042 https://reactome.org/PathwayBrowser/#/R-XTR-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Xenopus tropicalis 140187 R-BTA-9034053 https://reactome.org/PathwayBrowser/#/R-BTA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Bos taurus 140187 R-CFA-9034053 https://reactome.org/PathwayBrowser/#/R-CFA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Canis familiaris 140187 R-DRE-9034053 https://reactome.org/PathwayBrowser/#/R-DRE-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Danio rerio 140187 R-HSA-9034053 https://reactome.org/PathwayBrowser/#/R-HSA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen TAS Homo sapiens 140187 R-MMU-9034053 https://reactome.org/PathwayBrowser/#/R-MMU-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Mus musculus 140187 R-RNO-9034053 https://reactome.org/PathwayBrowser/#/R-RNO-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Rattus norvegicus 140187 R-XTR-9034053 https://reactome.org/PathwayBrowser/#/R-XTR-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Xenopus tropicalis 140192 R-BTA-9020257 https://reactome.org/PathwayBrowser/#/R-BTA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Bos taurus 140192 R-BTA-9020262 https://reactome.org/PathwayBrowser/#/R-BTA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Bos taurus 140192 R-CEL-9020257 https://reactome.org/PathwayBrowser/#/R-CEL-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Caenorhabditis elegans 140192 R-CFA-9020257 https://reactome.org/PathwayBrowser/#/R-CFA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Canis familiaris 140192 R-CFA-9020262 https://reactome.org/PathwayBrowser/#/R-CFA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Canis familiaris 140192 R-DDI-9020257 https://reactome.org/PathwayBrowser/#/R-DDI-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Dictyostelium discoideum 140192 R-DDI-9020262 https://reactome.org/PathwayBrowser/#/R-DDI-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Dictyostelium discoideum 140192 R-DME-9020257 https://reactome.org/PathwayBrowser/#/R-DME-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Drosophila melanogaster 140192 R-DRE-9020257 https://reactome.org/PathwayBrowser/#/R-DRE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Danio rerio 140192 R-DRE-9020262 https://reactome.org/PathwayBrowser/#/R-DRE-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Danio rerio 140192 R-GGA-9020257 https://reactome.org/PathwayBrowser/#/R-GGA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Gallus gallus 140192 R-HSA-9020257 https://reactome.org/PathwayBrowser/#/R-HSA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 TAS Homo sapiens 140192 R-HSA-9020262 https://reactome.org/PathwayBrowser/#/R-HSA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA TAS Homo sapiens 140192 R-MMU-9020257 https://reactome.org/PathwayBrowser/#/R-MMU-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Mus musculus 140192 R-MMU-9020262 https://reactome.org/PathwayBrowser/#/R-MMU-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Mus musculus 140192 R-RNO-9020257 https://reactome.org/PathwayBrowser/#/R-RNO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Rattus norvegicus 140192 R-RNO-9020262 https://reactome.org/PathwayBrowser/#/R-RNO-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Rattus norvegicus 140192 R-SCE-9020257 https://reactome.org/PathwayBrowser/#/R-SCE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Saccharomyces cerevisiae 140192 R-SPO-9020257 https://reactome.org/PathwayBrowser/#/R-SPO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Schizosaccharomyces pombe 140192 R-SSC-9020257 https://reactome.org/PathwayBrowser/#/R-SSC-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Sus scrofa 140192 R-SSC-9020262 https://reactome.org/PathwayBrowser/#/R-SSC-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Sus scrofa 140192 R-XTR-9020257 https://reactome.org/PathwayBrowser/#/R-XTR-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Xenopus tropicalis 140193 R-HSA-9025007 https://reactome.org/PathwayBrowser/#/R-HSA-9025007 Hydroperoxy reductase reduces 7(S),14(S)-diHp-DHA to 7-epi-MaR1 TAS Homo sapiens 140193 R-HSA-9026544 https://reactome.org/PathwayBrowser/#/R-HSA-9026544 Non-enzymatic hydrolysis hydrolyses 13(S),14(S)-epoxy-DHA to 7-epi-MaR1 TAS Homo sapiens 140193 R-HSA-9031802 https://reactome.org/PathwayBrowser/#/R-HSA-9031802 Maresins translocate from cytosol to extracellular region TAS Homo sapiens 140196 R-BTA-9024997 https://reactome.org/PathwayBrowser/#/R-BTA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Bos taurus 140196 R-CFA-9024997 https://reactome.org/PathwayBrowser/#/R-CFA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Canis familiaris 140196 R-DDI-9024997 https://reactome.org/PathwayBrowser/#/R-DDI-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Dictyostelium discoideum 140196 R-DRE-9024997 https://reactome.org/PathwayBrowser/#/R-DRE-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Danio rerio 140196 R-GGA-9024997 https://reactome.org/PathwayBrowser/#/R-GGA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Gallus gallus 140196 R-HSA-9024997 https://reactome.org/PathwayBrowser/#/R-HSA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA TAS Homo sapiens 140196 R-HSA-9025007 https://reactome.org/PathwayBrowser/#/R-HSA-9025007 Hydroperoxy reductase reduces 7(S),14(S)-diHp-DHA to 7-epi-MaR1 TAS Homo sapiens 140196 R-MMU-9024997 https://reactome.org/PathwayBrowser/#/R-MMU-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Mus musculus 140196 R-RNO-9024997 https://reactome.org/PathwayBrowser/#/R-RNO-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Rattus norvegicus 140196 R-SSC-9024997 https://reactome.org/PathwayBrowser/#/R-SSC-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Sus scrofa 140196 R-XTR-9024997 https://reactome.org/PathwayBrowser/#/R-XTR-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Xenopus tropicalis 140200 R-BTA-9026007 https://reactome.org/PathwayBrowser/#/R-BTA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Bos taurus 140200 R-CFA-9026007 https://reactome.org/PathwayBrowser/#/R-CFA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Canis familiaris 140200 R-DDI-9026007 https://reactome.org/PathwayBrowser/#/R-DDI-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Dictyostelium discoideum 140200 R-DRE-9026007 https://reactome.org/PathwayBrowser/#/R-DRE-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Danio rerio 140200 R-HSA-9025998 https://reactome.org/PathwayBrowser/#/R-HSA-9025998 Epoxide hydrolase hydrolyses 13,14-epoxy-DPAn-3 to MaR1n-3 DPA or MaR2n-3 DPA TAS Homo sapiens 140200 R-HSA-9026007 https://reactome.org/PathwayBrowser/#/R-HSA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 TAS Homo sapiens 140200 R-MMU-9026007 https://reactome.org/PathwayBrowser/#/R-MMU-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Mus musculus 140200 R-RNO-9026007 https://reactome.org/PathwayBrowser/#/R-RNO-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Rattus norvegicus 140200 R-SSC-9026007 https://reactome.org/PathwayBrowser/#/R-SSC-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Sus scrofa 140202 R-BTA-9020257 https://reactome.org/PathwayBrowser/#/R-BTA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Bos taurus 140202 R-CEL-9020257 https://reactome.org/PathwayBrowser/#/R-CEL-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Caenorhabditis elegans 140202 R-CFA-9020257 https://reactome.org/PathwayBrowser/#/R-CFA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Canis familiaris 140202 R-DDI-9020257 https://reactome.org/PathwayBrowser/#/R-DDI-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Dictyostelium discoideum 140202 R-DME-9020257 https://reactome.org/PathwayBrowser/#/R-DME-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Drosophila melanogaster 140202 R-DRE-9020257 https://reactome.org/PathwayBrowser/#/R-DRE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Danio rerio 140202 R-GGA-9020257 https://reactome.org/PathwayBrowser/#/R-GGA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Gallus gallus 140202 R-HSA-9020257 https://reactome.org/PathwayBrowser/#/R-HSA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 TAS Homo sapiens 140202 R-HSA-9031807 https://reactome.org/PathwayBrowser/#/R-HSA-9031807 Protectins translocate from cytosol to extracellular region TAS Homo sapiens 140202 R-MMU-9020257 https://reactome.org/PathwayBrowser/#/R-MMU-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Mus musculus 140202 R-RNO-9020257 https://reactome.org/PathwayBrowser/#/R-RNO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Rattus norvegicus 140202 R-SCE-9020257 https://reactome.org/PathwayBrowser/#/R-SCE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Saccharomyces cerevisiae 140202 R-SPO-9020257 https://reactome.org/PathwayBrowser/#/R-SPO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Schizosaccharomyces pombe 140202 R-SSC-9020257 https://reactome.org/PathwayBrowser/#/R-SSC-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Sus scrofa 140202 R-XTR-9020257 https://reactome.org/PathwayBrowser/#/R-XTR-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Xenopus tropicalis 140204 R-HSA-9027531 https://reactome.org/PathwayBrowser/#/R-HSA-9027531 Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA TAS Homo sapiens 140204 R-HSA-9032315 https://reactome.org/PathwayBrowser/#/R-HSA-9032315 oxo-DHAs translocate from cytosol to extracellular region TAS Homo sapiens 140205 R-HSA-9027598 https://reactome.org/PathwayBrowser/#/R-HSA-9027598 Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3 TAS Homo sapiens 140205 R-HSA-9032323 https://reactome.org/PathwayBrowser/#/R-HSA-9032323 oxo-DPAn-3s translocate from cytosol to extracellular region TAS Homo sapiens 140218 R-BTA-9025957 https://reactome.org/PathwayBrowser/#/R-BTA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Bos taurus 140218 R-CFA-9025957 https://reactome.org/PathwayBrowser/#/R-CFA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Canis familiaris 140218 R-DDI-9025957 https://reactome.org/PathwayBrowser/#/R-DDI-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Dictyostelium discoideum 140218 R-DRE-9025957 https://reactome.org/PathwayBrowser/#/R-DRE-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Danio rerio 140218 R-HSA-9025957 https://reactome.org/PathwayBrowser/#/R-HSA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 TAS Homo sapiens 140218 R-HSA-9031884 https://reactome.org/PathwayBrowser/#/R-HSA-9031884 DPAn-6 SPMs translocate from cytosol to extracellular region TAS Homo sapiens 140218 R-MMU-9025957 https://reactome.org/PathwayBrowser/#/R-MMU-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Mus musculus 140218 R-RNO-9025957 https://reactome.org/PathwayBrowser/#/R-RNO-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Rattus norvegicus 140218 R-SSC-9025957 https://reactome.org/PathwayBrowser/#/R-SSC-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Sus scrofa 140220 R-BTA-9020274 https://reactome.org/PathwayBrowser/#/R-BTA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Bos taurus 140220 R-BTA-9024983 https://reactome.org/PathwayBrowser/#/R-BTA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Bos taurus 140220 R-BTA-9024997 https://reactome.org/PathwayBrowser/#/R-BTA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Bos taurus 140220 R-BTA-9026007 https://reactome.org/PathwayBrowser/#/R-BTA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Bos taurus 140220 R-CFA-9020274 https://reactome.org/PathwayBrowser/#/R-CFA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Canis familiaris 140220 R-CFA-9024983 https://reactome.org/PathwayBrowser/#/R-CFA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Canis familiaris 140220 R-CFA-9024997 https://reactome.org/PathwayBrowser/#/R-CFA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Canis familiaris 140220 R-CFA-9026007 https://reactome.org/PathwayBrowser/#/R-CFA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Canis familiaris 140220 R-DDI-9020274 https://reactome.org/PathwayBrowser/#/R-DDI-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Dictyostelium discoideum 140220 R-DDI-9024983 https://reactome.org/PathwayBrowser/#/R-DDI-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Dictyostelium discoideum 140220 R-DDI-9024997 https://reactome.org/PathwayBrowser/#/R-DDI-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Dictyostelium discoideum 140220 R-DDI-9026007 https://reactome.org/PathwayBrowser/#/R-DDI-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Dictyostelium discoideum 140220 R-DRE-9020274 https://reactome.org/PathwayBrowser/#/R-DRE-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Danio rerio 140220 R-DRE-9024983 https://reactome.org/PathwayBrowser/#/R-DRE-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Danio rerio 140220 R-DRE-9024997 https://reactome.org/PathwayBrowser/#/R-DRE-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Danio rerio 140220 R-DRE-9026007 https://reactome.org/PathwayBrowser/#/R-DRE-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Danio rerio 140220 R-GGA-9024997 https://reactome.org/PathwayBrowser/#/R-GGA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Gallus gallus 140220 R-HSA-9020274 https://reactome.org/PathwayBrowser/#/R-HSA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA TAS Homo sapiens 140220 R-HSA-9024983 https://reactome.org/PathwayBrowser/#/R-HSA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA TAS Homo sapiens 140220 R-HSA-9024997 https://reactome.org/PathwayBrowser/#/R-HSA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA TAS Homo sapiens 140220 R-HSA-9026007 https://reactome.org/PathwayBrowser/#/R-HSA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 TAS Homo sapiens 140220 R-HSA-9027033 https://reactome.org/PathwayBrowser/#/R-HSA-9027033 Hydroperoxy reducatase reduces 14(S)-Hp-DHA to 14(S)-HDHA TAS Homo sapiens 140220 R-MMU-9020274 https://reactome.org/PathwayBrowser/#/R-MMU-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Mus musculus 140220 R-MMU-9024983 https://reactome.org/PathwayBrowser/#/R-MMU-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Mus musculus 140220 R-MMU-9024997 https://reactome.org/PathwayBrowser/#/R-MMU-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Mus musculus 140220 R-MMU-9026007 https://reactome.org/PathwayBrowser/#/R-MMU-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Mus musculus 140220 R-RNO-9020274 https://reactome.org/PathwayBrowser/#/R-RNO-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Rattus norvegicus 140220 R-RNO-9024983 https://reactome.org/PathwayBrowser/#/R-RNO-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Rattus norvegicus 140220 R-RNO-9024997 https://reactome.org/PathwayBrowser/#/R-RNO-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Rattus norvegicus 140220 R-RNO-9026007 https://reactome.org/PathwayBrowser/#/R-RNO-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Rattus norvegicus 140220 R-SSC-9020274 https://reactome.org/PathwayBrowser/#/R-SSC-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Sus scrofa 140220 R-SSC-9024983 https://reactome.org/PathwayBrowser/#/R-SSC-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Sus scrofa 140220 R-SSC-9024997 https://reactome.org/PathwayBrowser/#/R-SSC-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Sus scrofa 140220 R-SSC-9026007 https://reactome.org/PathwayBrowser/#/R-SSC-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Sus scrofa 140220 R-XTR-9024997 https://reactome.org/PathwayBrowser/#/R-XTR-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Xenopus tropicalis 140222 R-BTA-9026005 https://reactome.org/PathwayBrowser/#/R-BTA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Bos taurus 140222 R-BTA-9026006 https://reactome.org/PathwayBrowser/#/R-BTA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Bos taurus 140222 R-CFA-9026005 https://reactome.org/PathwayBrowser/#/R-CFA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Canis familiaris 140222 R-CFA-9026006 https://reactome.org/PathwayBrowser/#/R-CFA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Canis familiaris 140222 R-DDI-9026005 https://reactome.org/PathwayBrowser/#/R-DDI-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Dictyostelium discoideum 140222 R-DDI-9026006 https://reactome.org/PathwayBrowser/#/R-DDI-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Dictyostelium discoideum 140222 R-DRE-9026005 https://reactome.org/PathwayBrowser/#/R-DRE-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Danio rerio 140222 R-DRE-9026006 https://reactome.org/PathwayBrowser/#/R-DRE-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Danio rerio 140222 R-GGA-9026005 https://reactome.org/PathwayBrowser/#/R-GGA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Gallus gallus 140222 R-HSA-9026005 https://reactome.org/PathwayBrowser/#/R-HSA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA TAS Homo sapiens 140222 R-HSA-9026006 https://reactome.org/PathwayBrowser/#/R-HSA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 TAS Homo sapiens 140222 R-MMU-9026005 https://reactome.org/PathwayBrowser/#/R-MMU-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Mus musculus 140222 R-MMU-9026006 https://reactome.org/PathwayBrowser/#/R-MMU-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Mus musculus 140222 R-RNO-9026005 https://reactome.org/PathwayBrowser/#/R-RNO-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Rattus norvegicus 140222 R-RNO-9026006 https://reactome.org/PathwayBrowser/#/R-RNO-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Rattus norvegicus 140222 R-SSC-9026005 https://reactome.org/PathwayBrowser/#/R-SSC-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Sus scrofa 140222 R-SSC-9026006 https://reactome.org/PathwayBrowser/#/R-SSC-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Sus scrofa 140222 R-XTR-9026005 https://reactome.org/PathwayBrowser/#/R-XTR-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Xenopus tropicalis 140223 R-HSA-9028260 https://reactome.org/PathwayBrowser/#/R-HSA-9028260 δ12-PGJ3 spontaneously dehydrates to 15d-PGJ3 TAS Homo sapiens 140223 R-HSA-9032327 https://reactome.org/PathwayBrowser/#/R-HSA-9032327 5-oxo-EPA, 15d-PGJ3 translocate from cytosol to extracellular region TAS Homo sapiens 140224 R-BTA-9025999 https://reactome.org/PathwayBrowser/#/R-BTA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Bos taurus 140224 R-CFA-9025999 https://reactome.org/PathwayBrowser/#/R-CFA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Canis familiaris 140224 R-DDI-9025999 https://reactome.org/PathwayBrowser/#/R-DDI-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Dictyostelium discoideum 140224 R-DRE-9025999 https://reactome.org/PathwayBrowser/#/R-DRE-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Danio rerio 140224 R-GGA-9025999 https://reactome.org/PathwayBrowser/#/R-GGA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Gallus gallus 140224 R-HSA-9025999 https://reactome.org/PathwayBrowser/#/R-HSA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 TAS Homo sapiens 140224 R-HSA-9026000 https://reactome.org/PathwayBrowser/#/R-HSA-9026000 Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA TAS Homo sapiens 140224 R-MMU-9025999 https://reactome.org/PathwayBrowser/#/R-MMU-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Mus musculus 140224 R-RNO-9025999 https://reactome.org/PathwayBrowser/#/R-RNO-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Rattus norvegicus 140224 R-SSC-9025999 https://reactome.org/PathwayBrowser/#/R-SSC-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Sus scrofa 140224 R-XTR-9025999 https://reactome.org/PathwayBrowser/#/R-XTR-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Xenopus tropicalis 140225 R-BTA-9024881 https://reactome.org/PathwayBrowser/#/R-BTA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Bos taurus 140225 R-BTA-9024890 https://reactome.org/PathwayBrowser/#/R-BTA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Bos taurus 140225 R-CEL-9024890 https://reactome.org/PathwayBrowser/#/R-CEL-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Caenorhabditis elegans 140225 R-CFA-9024881 https://reactome.org/PathwayBrowser/#/R-CFA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Canis familiaris 140225 R-CFA-9024890 https://reactome.org/PathwayBrowser/#/R-CFA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Canis familiaris 140225 R-DDI-9024881 https://reactome.org/PathwayBrowser/#/R-DDI-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Dictyostelium discoideum 140225 R-DDI-9024890 https://reactome.org/PathwayBrowser/#/R-DDI-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Dictyostelium discoideum 140225 R-DME-9024890 https://reactome.org/PathwayBrowser/#/R-DME-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Drosophila melanogaster 140225 R-DRE-9024881 https://reactome.org/PathwayBrowser/#/R-DRE-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Danio rerio 140225 R-DRE-9024890 https://reactome.org/PathwayBrowser/#/R-DRE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Danio rerio 140225 R-GGA-9024890 https://reactome.org/PathwayBrowser/#/R-GGA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Gallus gallus 140225 R-HSA-9024881 https://reactome.org/PathwayBrowser/#/R-HSA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA TAS Homo sapiens 140225 R-HSA-9024890 https://reactome.org/PathwayBrowser/#/R-HSA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 TAS Homo sapiens 140225 R-HSA-9026901 https://reactome.org/PathwayBrowser/#/R-HSA-9026901 GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1 TAS Homo sapiens 140225 R-MMU-9024881 https://reactome.org/PathwayBrowser/#/R-MMU-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Mus musculus 140225 R-MMU-9024890 https://reactome.org/PathwayBrowser/#/R-MMU-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Mus musculus 140225 R-RNO-9024881 https://reactome.org/PathwayBrowser/#/R-RNO-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Rattus norvegicus 140225 R-RNO-9024890 https://reactome.org/PathwayBrowser/#/R-RNO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Rattus norvegicus 140225 R-SCE-9024890 https://reactome.org/PathwayBrowser/#/R-SCE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Saccharomyces cerevisiae 140225 R-SPO-9024890 https://reactome.org/PathwayBrowser/#/R-SPO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Schizosaccharomyces pombe 140225 R-SSC-9024881 https://reactome.org/PathwayBrowser/#/R-SSC-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Sus scrofa 140225 R-SSC-9024890 https://reactome.org/PathwayBrowser/#/R-SSC-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Sus scrofa 140225 R-XTR-9024890 https://reactome.org/PathwayBrowser/#/R-XTR-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Xenopus tropicalis 140226 R-BTA-9025996 https://reactome.org/PathwayBrowser/#/R-BTA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Bos taurus 140226 R-BTA-9025999 https://reactome.org/PathwayBrowser/#/R-BTA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Bos taurus 140226 R-BTA-9026003 https://reactome.org/PathwayBrowser/#/R-BTA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Bos taurus 140226 R-CFA-9025996 https://reactome.org/PathwayBrowser/#/R-CFA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Canis familiaris 140226 R-CFA-9025999 https://reactome.org/PathwayBrowser/#/R-CFA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Canis familiaris 140226 R-CFA-9026003 https://reactome.org/PathwayBrowser/#/R-CFA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Canis familiaris 140226 R-DDI-9025996 https://reactome.org/PathwayBrowser/#/R-DDI-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Dictyostelium discoideum 140226 R-DDI-9025999 https://reactome.org/PathwayBrowser/#/R-DDI-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Dictyostelium discoideum 140226 R-DDI-9026003 https://reactome.org/PathwayBrowser/#/R-DDI-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Dictyostelium discoideum 140226 R-DRE-9025996 https://reactome.org/PathwayBrowser/#/R-DRE-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Danio rerio 140226 R-DRE-9025999 https://reactome.org/PathwayBrowser/#/R-DRE-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Danio rerio 140226 R-DRE-9026003 https://reactome.org/PathwayBrowser/#/R-DRE-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Danio rerio 140226 R-GGA-9025996 https://reactome.org/PathwayBrowser/#/R-GGA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Gallus gallus 140226 R-GGA-9025999 https://reactome.org/PathwayBrowser/#/R-GGA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Gallus gallus 140226 R-HSA-9025996 https://reactome.org/PathwayBrowser/#/R-HSA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 TAS Homo sapiens 140226 R-HSA-9025999 https://reactome.org/PathwayBrowser/#/R-HSA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 TAS Homo sapiens 140226 R-HSA-9026003 https://reactome.org/PathwayBrowser/#/R-HSA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 TAS Homo sapiens 140226 R-MMU-9025996 https://reactome.org/PathwayBrowser/#/R-MMU-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Mus musculus 140226 R-MMU-9025999 https://reactome.org/PathwayBrowser/#/R-MMU-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Mus musculus 140226 R-MMU-9026003 https://reactome.org/PathwayBrowser/#/R-MMU-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Mus musculus 140226 R-RNO-9025996 https://reactome.org/PathwayBrowser/#/R-RNO-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Rattus norvegicus 140226 R-RNO-9025999 https://reactome.org/PathwayBrowser/#/R-RNO-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Rattus norvegicus 140226 R-RNO-9026003 https://reactome.org/PathwayBrowser/#/R-RNO-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Rattus norvegicus 140226 R-SSC-9025996 https://reactome.org/PathwayBrowser/#/R-SSC-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Sus scrofa 140226 R-SSC-9025999 https://reactome.org/PathwayBrowser/#/R-SSC-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Sus scrofa 140226 R-SSC-9026003 https://reactome.org/PathwayBrowser/#/R-SSC-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Sus scrofa 140226 R-XTR-9025996 https://reactome.org/PathwayBrowser/#/R-XTR-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Xenopus tropicalis 140226 R-XTR-9025999 https://reactome.org/PathwayBrowser/#/R-XTR-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Xenopus tropicalis 140234 R-BTA-9025995 https://reactome.org/PathwayBrowser/#/R-BTA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Bos taurus 140234 R-CFA-9025995 https://reactome.org/PathwayBrowser/#/R-CFA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Canis familiaris 140234 R-DDI-9025995 https://reactome.org/PathwayBrowser/#/R-DDI-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Dictyostelium discoideum 140234 R-DRE-9025995 https://reactome.org/PathwayBrowser/#/R-DRE-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Danio rerio 140234 R-GGA-9025995 https://reactome.org/PathwayBrowser/#/R-GGA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Gallus gallus 140234 R-HSA-9025995 https://reactome.org/PathwayBrowser/#/R-HSA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 TAS Homo sapiens 140234 R-HSA-9026008 https://reactome.org/PathwayBrowser/#/R-HSA-9026008 Epoxide hydrolase hydrolyses 7,8-epoxy-HDPAn-3 to RvD1n-3DPA or RvD2n-3DPA TAS Homo sapiens 140234 R-MMU-9025995 https://reactome.org/PathwayBrowser/#/R-MMU-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Mus musculus 140234 R-RNO-9025995 https://reactome.org/PathwayBrowser/#/R-RNO-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Rattus norvegicus 140234 R-SSC-9025995 https://reactome.org/PathwayBrowser/#/R-SSC-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Sus scrofa 140234 R-XTR-9025995 https://reactome.org/PathwayBrowser/#/R-XTR-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Xenopus tropicalis 140238 R-HSA-9027562 https://reactome.org/PathwayBrowser/#/R-HSA-9027562 Dehydrogenase dehydrogenates 17-HDHA to 17-oxo-DHA TAS Homo sapiens 140238 R-HSA-9032315 https://reactome.org/PathwayBrowser/#/R-HSA-9032315 oxo-DHAs translocate from cytosol to extracellular region TAS Homo sapiens 140239 R-HSA-9027600 https://reactome.org/PathwayBrowser/#/R-HSA-9027600 Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3 TAS Homo sapiens 140239 R-HSA-9032323 https://reactome.org/PathwayBrowser/#/R-HSA-9032323 oxo-DPAn-3s translocate from cytosol to extracellular region TAS Homo sapiens 140243 R-BTA-9037761 https://reactome.org/PathwayBrowser/#/R-BTA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Bos taurus 140243 R-DRE-9037761 https://reactome.org/PathwayBrowser/#/R-DRE-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Danio rerio 140243 R-GGA-9037761 https://reactome.org/PathwayBrowser/#/R-GGA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Gallus gallus 140243 R-HSA-9031807 https://reactome.org/PathwayBrowser/#/R-HSA-9031807 Protectins translocate from cytosol to extracellular region TAS Homo sapiens 140243 R-HSA-9037761 https://reactome.org/PathwayBrowser/#/R-HSA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 TAS Homo sapiens 140243 R-MMU-9037761 https://reactome.org/PathwayBrowser/#/R-MMU-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Mus musculus 140243 R-RNO-9037761 https://reactome.org/PathwayBrowser/#/R-RNO-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Rattus norvegicus 140243 R-SSC-9037761 https://reactome.org/PathwayBrowser/#/R-SSC-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Sus scrofa 140244 R-HSA-9027632 https://reactome.org/PathwayBrowser/#/R-HSA-9027632 5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA TAS Homo sapiens 140244 R-HSA-9032327 https://reactome.org/PathwayBrowser/#/R-HSA-9032327 5-oxo-EPA, 15d-PGJ3 translocate from cytosol to extracellular region TAS Homo sapiens 140245 R-HSA-9026917 https://reactome.org/PathwayBrowser/#/R-HSA-9026917 Lipoxygenase dehydrogenates 7(S),17(S)-diHp-DHA to 7S(8)-epoxy-17(S)-HDHA TAS Homo sapiens 140245 R-HSA-9026918 https://reactome.org/PathwayBrowser/#/R-HSA-9026918 Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA TAS Homo sapiens 140248 R-BTA-9025995 https://reactome.org/PathwayBrowser/#/R-BTA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Bos taurus 140248 R-BTA-9025996 https://reactome.org/PathwayBrowser/#/R-BTA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Bos taurus 140248 R-CFA-9025995 https://reactome.org/PathwayBrowser/#/R-CFA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Canis familiaris 140248 R-CFA-9025996 https://reactome.org/PathwayBrowser/#/R-CFA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Canis familiaris 140248 R-DDI-9025995 https://reactome.org/PathwayBrowser/#/R-DDI-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Dictyostelium discoideum 140248 R-DDI-9025996 https://reactome.org/PathwayBrowser/#/R-DDI-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Dictyostelium discoideum 140248 R-DRE-9025995 https://reactome.org/PathwayBrowser/#/R-DRE-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Danio rerio 140248 R-DRE-9025996 https://reactome.org/PathwayBrowser/#/R-DRE-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Danio rerio 140248 R-GGA-9025995 https://reactome.org/PathwayBrowser/#/R-GGA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Gallus gallus 140248 R-GGA-9025996 https://reactome.org/PathwayBrowser/#/R-GGA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Gallus gallus 140248 R-HSA-9025995 https://reactome.org/PathwayBrowser/#/R-HSA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 TAS Homo sapiens 140248 R-HSA-9025996 https://reactome.org/PathwayBrowser/#/R-HSA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 TAS Homo sapiens 140248 R-HSA-9026001 https://reactome.org/PathwayBrowser/#/R-HSA-9026001 Hydroperoxy reductase reduces 7,17-diHp-DPAn-3 to RvD5n-3DPA TAS Homo sapiens 140248 R-MMU-9025995 https://reactome.org/PathwayBrowser/#/R-MMU-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Mus musculus 140248 R-MMU-9025996 https://reactome.org/PathwayBrowser/#/R-MMU-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Mus musculus 140248 R-RNO-9025995 https://reactome.org/PathwayBrowser/#/R-RNO-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Rattus norvegicus 140248 R-RNO-9025996 https://reactome.org/PathwayBrowser/#/R-RNO-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Rattus norvegicus 140248 R-SSC-9025995 https://reactome.org/PathwayBrowser/#/R-SSC-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Sus scrofa 140248 R-SSC-9025996 https://reactome.org/PathwayBrowser/#/R-SSC-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Sus scrofa 140248 R-XTR-9025995 https://reactome.org/PathwayBrowser/#/R-XTR-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Xenopus tropicalis 140248 R-XTR-9025996 https://reactome.org/PathwayBrowser/#/R-XTR-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Xenopus tropicalis 140250 R-BTA-9027633 https://reactome.org/PathwayBrowser/#/R-BTA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Bos taurus 140250 R-CFA-9027633 https://reactome.org/PathwayBrowser/#/R-CFA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Canis familiaris 140250 R-DDI-9027633 https://reactome.org/PathwayBrowser/#/R-DDI-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Dictyostelium discoideum 140250 R-DRE-9027633 https://reactome.org/PathwayBrowser/#/R-DRE-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Danio rerio 140250 R-GGA-9027633 https://reactome.org/PathwayBrowser/#/R-GGA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Gallus gallus 140250 R-HSA-9027625 https://reactome.org/PathwayBrowser/#/R-HSA-9027625 5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3 TAS Homo sapiens 140250 R-HSA-9027633 https://reactome.org/PathwayBrowser/#/R-HSA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 TAS Homo sapiens 140250 R-MMU-9027633 https://reactome.org/PathwayBrowser/#/R-MMU-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Mus musculus 140250 R-RNO-9027633 https://reactome.org/PathwayBrowser/#/R-RNO-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Rattus norvegicus 140250 R-SSC-9027633 https://reactome.org/PathwayBrowser/#/R-SSC-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Sus scrofa 140250 R-XTR-9027633 https://reactome.org/PathwayBrowser/#/R-XTR-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Xenopus tropicalis 140252 R-HSA-9027631 https://reactome.org/PathwayBrowser/#/R-HSA-9027631 5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA TAS Homo sapiens 140252 R-HSA-9032315 https://reactome.org/PathwayBrowser/#/R-HSA-9032315 oxo-DHAs translocate from cytosol to extracellular region TAS Homo sapiens 140253 R-HSA-9027625 https://reactome.org/PathwayBrowser/#/R-HSA-9027625 5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3 TAS Homo sapiens 140253 R-HSA-9032323 https://reactome.org/PathwayBrowser/#/R-HSA-9032323 oxo-DPAn-3s translocate from cytosol to extracellular region TAS Homo sapiens 140256 R-HSA-9025998 https://reactome.org/PathwayBrowser/#/R-HSA-9025998 Epoxide hydrolase hydrolyses 13,14-epoxy-DPAn-3 to MaR1n-3 DPA or MaR2n-3 DPA TAS Homo sapiens 140256 R-HSA-9031894 https://reactome.org/PathwayBrowser/#/R-HSA-9031894 DPAn-3 maresins translocate from cytosol to extracellular region TAS Homo sapiens 140257 R-HSA-9025998 https://reactome.org/PathwayBrowser/#/R-HSA-9025998 Epoxide hydrolase hydrolyses 13,14-epoxy-DPAn-3 to MaR1n-3 DPA or MaR2n-3 DPA TAS Homo sapiens 140257 R-HSA-9031894 https://reactome.org/PathwayBrowser/#/R-HSA-9031894 DPAn-3 maresins translocate from cytosol to extracellular region TAS Homo sapiens 140258 R-BTA-9026005 https://reactome.org/PathwayBrowser/#/R-BTA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Bos taurus 140258 R-CFA-9026005 https://reactome.org/PathwayBrowser/#/R-CFA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Canis familiaris 140258 R-DDI-9026005 https://reactome.org/PathwayBrowser/#/R-DDI-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Dictyostelium discoideum 140258 R-DRE-9026005 https://reactome.org/PathwayBrowser/#/R-DRE-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Danio rerio 140258 R-GGA-9026005 https://reactome.org/PathwayBrowser/#/R-GGA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Gallus gallus 140258 R-HSA-9026005 https://reactome.org/PathwayBrowser/#/R-HSA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA TAS Homo sapiens 140258 R-HSA-9031894 https://reactome.org/PathwayBrowser/#/R-HSA-9031894 DPAn-3 maresins translocate from cytosol to extracellular region TAS Homo sapiens 140258 R-MMU-9026005 https://reactome.org/PathwayBrowser/#/R-MMU-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Mus musculus 140258 R-RNO-9026005 https://reactome.org/PathwayBrowser/#/R-RNO-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Rattus norvegicus 140258 R-SSC-9026005 https://reactome.org/PathwayBrowser/#/R-SSC-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Sus scrofa 140258 R-XTR-9026005 https://reactome.org/PathwayBrowser/#/R-XTR-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Xenopus tropicalis 140262 R-HSA-9026901 https://reactome.org/PathwayBrowser/#/R-HSA-9026901 GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1 TAS Homo sapiens 140262 R-HSA-9026912 https://reactome.org/PathwayBrowser/#/R-HSA-9026912 GGT hydrolyses PCTR1 to PCTR2 TAS Homo sapiens 140262 R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140263 R-HSA-9026907 https://reactome.org/PathwayBrowser/#/R-HSA-9026907 GGT hydrolyses PCTR2 to PCTR3 TAS Homo sapiens 140263 R-HSA-9026912 https://reactome.org/PathwayBrowser/#/R-HSA-9026912 GGT hydrolyses PCTR1 to PCTR2 TAS Homo sapiens 140263 R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140264 R-HSA-9026907 https://reactome.org/PathwayBrowser/#/R-HSA-9026907 GGT hydrolyses PCTR2 to PCTR3 TAS Homo sapiens 140264 R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140265 R-HSA-9026000 https://reactome.org/PathwayBrowser/#/R-HSA-9026000 Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA TAS Homo sapiens 140265 R-HSA-9031896 https://reactome.org/PathwayBrowser/#/R-HSA-9031896 PD1n-3, PD2n-3 translocate from cytosol to extracellular region TAS Homo sapiens 140266 R-HSA-9026000 https://reactome.org/PathwayBrowser/#/R-HSA-9026000 Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA TAS Homo sapiens 140266 R-HSA-9031896 https://reactome.org/PathwayBrowser/#/R-HSA-9031896 PD1n-3, PD2n-3 translocate from cytosol to extracellular region TAS Homo sapiens 140267 R-HSA-9028263 https://reactome.org/PathwayBrowser/#/R-HSA-9028263 PGJ3 isomerises to δ12-PGJ3 TAS Homo sapiens 140267 R-HSA-9028273 https://reactome.org/PathwayBrowser/#/R-HSA-9028273 PGH3 spontaneously dehydrates to PGJ3 TAS Homo sapiens 140268 R-BTA-9026911 https://reactome.org/PathwayBrowser/#/R-BTA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Bos taurus 140268 R-CFA-9026911 https://reactome.org/PathwayBrowser/#/R-CFA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Canis familiaris 140268 R-DDI-9026911 https://reactome.org/PathwayBrowser/#/R-DDI-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Dictyostelium discoideum 140268 R-GGA-9026911 https://reactome.org/PathwayBrowser/#/R-GGA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Gallus gallus 140268 R-HSA-9026911 https://reactome.org/PathwayBrowser/#/R-HSA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 TAS Homo sapiens 140268 R-HSA-9026927 https://reactome.org/PathwayBrowser/#/R-HSA-9026927 GGT hydrolyses RCTR1 to RCTR2 TAS Homo sapiens 140268 R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140268 R-MMU-9026911 https://reactome.org/PathwayBrowser/#/R-MMU-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Mus musculus 140268 R-RNO-9026911 https://reactome.org/PathwayBrowser/#/R-RNO-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Rattus norvegicus 140268 R-SSC-9026911 https://reactome.org/PathwayBrowser/#/R-SSC-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Sus scrofa 140268 R-XTR-9026911 https://reactome.org/PathwayBrowser/#/R-XTR-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Xenopus tropicalis 140269 R-HSA-9026916 https://reactome.org/PathwayBrowser/#/R-HSA-9026916 GGT hydrolyses RCTR2 to RCTR3 TAS Homo sapiens 140269 R-HSA-9026927 https://reactome.org/PathwayBrowser/#/R-HSA-9026927 GGT hydrolyses RCTR1 to RCTR2 TAS Homo sapiens 140269 R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140270 R-HSA-9026916 https://reactome.org/PathwayBrowser/#/R-HSA-9026916 GGT hydrolyses RCTR2 to RCTR3 TAS Homo sapiens 140270 R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140271 R-HSA-9026008 https://reactome.org/PathwayBrowser/#/R-HSA-9026008 Epoxide hydrolase hydrolyses 7,8-epoxy-HDPAn-3 to RvD1n-3DPA or RvD2n-3DPA TAS Homo sapiens 140271 R-HSA-9031881 https://reactome.org/PathwayBrowser/#/R-HSA-9031881 DPAn-3 resolvins translocate from cytosol to extracellular region TAS Homo sapiens 140272 R-HSA-9026008 https://reactome.org/PathwayBrowser/#/R-HSA-9026008 Epoxide hydrolase hydrolyses 7,8-epoxy-HDPAn-3 to RvD1n-3DPA or RvD2n-3DPA TAS Homo sapiens 140272 R-HSA-9031881 https://reactome.org/PathwayBrowser/#/R-HSA-9031881 DPAn-3 resolvins translocate from cytosol to extracellular region TAS Homo sapiens 140273 R-HSA-9026001 https://reactome.org/PathwayBrowser/#/R-HSA-9026001 Hydroperoxy reductase reduces 7,17-diHp-DPAn-3 to RvD5n-3DPA TAS Homo sapiens 140273 R-HSA-9031881 https://reactome.org/PathwayBrowser/#/R-HSA-9031881 DPAn-3 resolvins translocate from cytosol to extracellular region TAS Homo sapiens 140274 R-HSA-9028260 https://reactome.org/PathwayBrowser/#/R-HSA-9028260 δ12-PGJ3 spontaneously dehydrates to 15d-PGJ3 TAS Homo sapiens 140274 R-HSA-9028263 https://reactome.org/PathwayBrowser/#/R-HSA-9028263 PGJ3 isomerises to δ12-PGJ3 TAS Homo sapiens 140296 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 140296 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 140296 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 140296 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 140296 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 140296 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 140296 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 140296 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 140296 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 140296 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 140296 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 140296 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 140296 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 140296 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 140296 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 140296 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 140296 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 140296 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 140296 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 140296 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 140296 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 140296 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 140296 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 140296 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 140296 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 140296 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 140296 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 140296 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 140296 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 140296 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 140296 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 140296 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 140296 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 140372 R-BTA-1855165 https://reactome.org/PathwayBrowser/#/R-BTA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 140372 R-BTA-2023973 https://reactome.org/PathwayBrowser/#/R-BTA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 140372 R-CEL-1855165 https://reactome.org/PathwayBrowser/#/R-CEL-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 140372 R-CEL-2023973 https://reactome.org/PathwayBrowser/#/R-CEL-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 140372 R-CFA-1855165 https://reactome.org/PathwayBrowser/#/R-CFA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 140372 R-CFA-2023973 https://reactome.org/PathwayBrowser/#/R-CFA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 140372 R-DDI-1855165 https://reactome.org/PathwayBrowser/#/R-DDI-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 140372 R-DDI-2023973 https://reactome.org/PathwayBrowser/#/R-DDI-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 140372 R-DME-1855165 https://reactome.org/PathwayBrowser/#/R-DME-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 140372 R-DME-2023973 https://reactome.org/PathwayBrowser/#/R-DME-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 140372 R-DRE-1855165 https://reactome.org/PathwayBrowser/#/R-DRE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 140372 R-DRE-2023973 https://reactome.org/PathwayBrowser/#/R-DRE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 140372 R-GGA-1855165 https://reactome.org/PathwayBrowser/#/R-GGA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 140372 R-GGA-2023973 https://reactome.org/PathwayBrowser/#/R-GGA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 140372 R-HSA-1855165 https://reactome.org/PathwayBrowser/#/R-HSA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 140372 R-HSA-1855220 https://reactome.org/PathwayBrowser/#/R-HSA-1855220 (PP)2-IP4 transports from the nucleus to the cytosol TAS Homo sapiens 140372 R-HSA-2023973 https://reactome.org/PathwayBrowser/#/R-HSA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 140372 R-MMU-1855165 https://reactome.org/PathwayBrowser/#/R-MMU-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 140372 R-MMU-2023973 https://reactome.org/PathwayBrowser/#/R-MMU-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 140372 R-RNO-1855165 https://reactome.org/PathwayBrowser/#/R-RNO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 140372 R-RNO-2023973 https://reactome.org/PathwayBrowser/#/R-RNO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 140372 R-SCE-1855165 https://reactome.org/PathwayBrowser/#/R-SCE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 140372 R-SCE-2023973 https://reactome.org/PathwayBrowser/#/R-SCE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 140372 R-SPO-1855165 https://reactome.org/PathwayBrowser/#/R-SPO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 140372 R-SPO-2023973 https://reactome.org/PathwayBrowser/#/R-SPO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 140372 R-SSC-1855165 https://reactome.org/PathwayBrowser/#/R-SSC-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 140372 R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 140372 R-XTR-1855165 https://reactome.org/PathwayBrowser/#/R-XTR-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 140372 R-XTR-2023973 https://reactome.org/PathwayBrowser/#/R-XTR-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 140374 R-BTA-2023971 https://reactome.org/PathwayBrowser/#/R-BTA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 140374 R-BTA-2023973 https://reactome.org/PathwayBrowser/#/R-BTA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 140374 R-CEL-2023971 https://reactome.org/PathwayBrowser/#/R-CEL-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 140374 R-CEL-2023973 https://reactome.org/PathwayBrowser/#/R-CEL-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 140374 R-CFA-2023971 https://reactome.org/PathwayBrowser/#/R-CFA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 140374 R-CFA-2023973 https://reactome.org/PathwayBrowser/#/R-CFA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 140374 R-DDI-2023971 https://reactome.org/PathwayBrowser/#/R-DDI-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 140374 R-DDI-2023973 https://reactome.org/PathwayBrowser/#/R-DDI-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 140374 R-DME-2023971 https://reactome.org/PathwayBrowser/#/R-DME-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 140374 R-DME-2023973 https://reactome.org/PathwayBrowser/#/R-DME-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 140374 R-DRE-2023971 https://reactome.org/PathwayBrowser/#/R-DRE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 140374 R-DRE-2023973 https://reactome.org/PathwayBrowser/#/R-DRE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 140374 R-GGA-2023971 https://reactome.org/PathwayBrowser/#/R-GGA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 140374 R-GGA-2023973 https://reactome.org/PathwayBrowser/#/R-GGA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 140374 R-HSA-1855212 https://reactome.org/PathwayBrowser/#/R-HSA-1855212 1/3-PP-IP5 transports from the cytosol to the nucleus TAS Homo sapiens 140374 R-HSA-2023971 https://reactome.org/PathwayBrowser/#/R-HSA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 140374 R-HSA-2023973 https://reactome.org/PathwayBrowser/#/R-HSA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 140374 R-MMU-2023971 https://reactome.org/PathwayBrowser/#/R-MMU-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 140374 R-MMU-2023973 https://reactome.org/PathwayBrowser/#/R-MMU-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 140374 R-RNO-2023971 https://reactome.org/PathwayBrowser/#/R-RNO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 140374 R-RNO-2023973 https://reactome.org/PathwayBrowser/#/R-RNO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 140374 R-SCE-2023971 https://reactome.org/PathwayBrowser/#/R-SCE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 140374 R-SCE-2023973 https://reactome.org/PathwayBrowser/#/R-SCE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 140374 R-SPO-2023971 https://reactome.org/PathwayBrowser/#/R-SPO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 140374 R-SPO-2023973 https://reactome.org/PathwayBrowser/#/R-SPO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 140374 R-SSC-2023971 https://reactome.org/PathwayBrowser/#/R-SSC-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 140374 R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 140374 R-XTR-2023971 https://reactome.org/PathwayBrowser/#/R-XTR-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 140374 R-XTR-2023973 https://reactome.org/PathwayBrowser/#/R-XTR-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 140420 R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 140420 R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 140420 R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 140420 R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 140420 R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 140420 R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 140420 R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 140420 R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 140420 R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 140420 R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 140420 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 140420 R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 140420 R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 140420 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 140420 R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 140420 R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 140420 R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 140420 R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 140420 R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 140420 R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 140420 R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 140420 R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 140420 R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 140420 R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 140420 R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 140420 R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 140420 R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 140420 R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 140420 R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 140420 R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 140421 R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 140421 R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 140421 R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 140421 R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 140421 R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 140421 R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 140421 R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 140421 R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 140421 R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 140421 R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 140421 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 140421 R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 140421 R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 140421 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 140421 R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 140421 R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 140421 R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 140421 R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 140421 R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 140421 R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 140421 R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 140421 R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 140421 R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 140421 R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 140421 R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 140421 R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 140421 R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 140421 R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 140421 R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 140421 R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 140427 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 140427 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 140427 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 140427 R-BTA-9603302 https://reactome.org/PathwayBrowser/#/R-BTA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Bos taurus 140427 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 140427 R-CFA-9603302 https://reactome.org/PathwayBrowser/#/R-CFA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Canis familiaris 140427 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 140427 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 140427 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 140427 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 140427 R-GGA-9603302 https://reactome.org/PathwayBrowser/#/R-GGA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Gallus gallus 140427 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 140427 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 140427 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 140427 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 140427 R-HSA-9603302 https://reactome.org/PathwayBrowser/#/R-HSA-9603302 Factor IIa inhibitors (peptide) binds IIa TAS Homo sapiens 140427 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 140427 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 140427 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 140427 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 140427 R-MMU-9603302 https://reactome.org/PathwayBrowser/#/R-MMU-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Mus musculus 140427 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 140427 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 140427 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 140427 R-RNO-9603302 https://reactome.org/PathwayBrowser/#/R-RNO-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Rattus norvegicus 140427 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 140427 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 140427 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 140427 R-SSC-9603302 https://reactome.org/PathwayBrowser/#/R-SSC-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Sus scrofa 140427 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 140427 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 140427 R-XTR-9603302 https://reactome.org/PathwayBrowser/#/R-XTR-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Xenopus tropicalis 140472 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 140472 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 140472 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 140472 R-BTA-9015379 https://reactome.org/PathwayBrowser/#/R-BTA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Bos taurus 140472 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 140472 R-CFA-9015379 https://reactome.org/PathwayBrowser/#/R-CFA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Canis familiaris 140472 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 140472 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 140472 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 140472 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 140472 R-GGA-9015379 https://reactome.org/PathwayBrowser/#/R-GGA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Gallus gallus 140472 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 140472 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 140472 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 140472 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 140472 R-HSA-9015379 https://reactome.org/PathwayBrowser/#/R-HSA-9015379 Factor IIa inhibitors (compounds) binds IIa TAS Homo sapiens 140472 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 140472 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 140472 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 140472 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 140472 R-MMU-9015379 https://reactome.org/PathwayBrowser/#/R-MMU-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Mus musculus 140472 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 140472 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 140472 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 140472 R-RNO-9015379 https://reactome.org/PathwayBrowser/#/R-RNO-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Rattus norvegicus 140472 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 140472 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 140472 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 140472 R-SSC-9015379 https://reactome.org/PathwayBrowser/#/R-SSC-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Sus scrofa 140472 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 140472 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 140472 R-XTR-9015379 https://reactome.org/PathwayBrowser/#/R-XTR-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Xenopus tropicalis 140785 R-BTA-3000074 https://reactome.org/PathwayBrowser/#/R-BTA-3000074 TCN2 binds RCbl in the circulation IEA Bos taurus 140785 R-BTA-3000103 https://reactome.org/PathwayBrowser/#/R-BTA-3000103 CUBN:AMN binds CBLIF:RCbl IEA Bos taurus 140785 R-BTA-3000112 https://reactome.org/PathwayBrowser/#/R-BTA-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Bos taurus 140785 R-BTA-3000120 https://reactome.org/PathwayBrowser/#/R-BTA-3000120 CBLIF binds RCbl IEA Bos taurus 140785 R-BTA-3000122 https://reactome.org/PathwayBrowser/#/R-BTA-3000122 CD320 binds extracellular TCN2:RCbl IEA Bos taurus 140785 R-BTA-3000137 https://reactome.org/PathwayBrowser/#/R-BTA-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome IEA Bos taurus 140785 R-BTA-3095889 https://reactome.org/PathwayBrowser/#/R-BTA-3095889 MMACHC dealkylates RCbl IEA Bos taurus 140785 R-BTA-3095901 https://reactome.org/PathwayBrowser/#/R-BTA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Bos taurus 140785 R-BTA-3132753 https://reactome.org/PathwayBrowser/#/R-BTA-3132753 Pancreatic proteases degrade TCN1:RCbl IEA Bos taurus 140785 R-BTA-3132759 https://reactome.org/PathwayBrowser/#/R-BTA-3132759 TCN1 binds RCbl IEA Bos taurus 140785 R-BTA-5223313 https://reactome.org/PathwayBrowser/#/R-BTA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Bos taurus 140785 R-BTA-9759202 https://reactome.org/PathwayBrowser/#/R-BTA-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Bos taurus 140785 R-BTA-9759206 https://reactome.org/PathwayBrowser/#/R-BTA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Bos taurus 140785 R-BTA-9759209 https://reactome.org/PathwayBrowser/#/R-BTA-9759209 LRP2 binds extracellular TCN2:RCbl IEA Bos taurus 140785 R-CEL-3095889 https://reactome.org/PathwayBrowser/#/R-CEL-3095889 MMACHC dealkylates RCbl IEA Caenorhabditis elegans 140785 R-CEL-3095901 https://reactome.org/PathwayBrowser/#/R-CEL-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Caenorhabditis elegans 140785 R-CFA-3000074 https://reactome.org/PathwayBrowser/#/R-CFA-3000074 TCN2 binds RCbl in the circulation IEA Canis familiaris 140785 R-CFA-3000112 https://reactome.org/PathwayBrowser/#/R-CFA-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Canis familiaris 140785 R-CFA-3000120 https://reactome.org/PathwayBrowser/#/R-CFA-3000120 CBLIF binds RCbl IEA Canis familiaris 140785 R-CFA-3000122 https://reactome.org/PathwayBrowser/#/R-CFA-3000122 CD320 binds extracellular TCN2:RCbl IEA Canis familiaris 140785 R-CFA-3095889 https://reactome.org/PathwayBrowser/#/R-CFA-3095889 MMACHC dealkylates RCbl IEA Canis familiaris 140785 R-CFA-3095901 https://reactome.org/PathwayBrowser/#/R-CFA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Canis familiaris 140785 R-CFA-3132753 https://reactome.org/PathwayBrowser/#/R-CFA-3132753 Pancreatic proteases degrade TCN1:RCbl IEA Canis familiaris 140785 R-CFA-3132759 https://reactome.org/PathwayBrowser/#/R-CFA-3132759 TCN1 binds RCbl IEA Canis familiaris 140785 R-CFA-5223313 https://reactome.org/PathwayBrowser/#/R-CFA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Canis familiaris 140785 R-CFA-9759202 https://reactome.org/PathwayBrowser/#/R-CFA-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Canis familiaris 140785 R-CFA-9759206 https://reactome.org/PathwayBrowser/#/R-CFA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Canis familiaris 140785 R-CFA-9759209 https://reactome.org/PathwayBrowser/#/R-CFA-9759209 LRP2 binds extracellular TCN2:RCbl IEA Canis familiaris 140785 R-DDI-3095889 https://reactome.org/PathwayBrowser/#/R-DDI-3095889 MMACHC dealkylates RCbl IEA Dictyostelium discoideum 140785 R-DDI-3095901 https://reactome.org/PathwayBrowser/#/R-DDI-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Dictyostelium discoideum 140785 R-DDI-5223313 https://reactome.org/PathwayBrowser/#/R-DDI-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Dictyostelium discoideum 140785 R-DDI-9759206 https://reactome.org/PathwayBrowser/#/R-DDI-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Dictyostelium discoideum 140785 R-DME-3000074 https://reactome.org/PathwayBrowser/#/R-DME-3000074 TCN2 binds RCbl in the circulation IEA Drosophila melanogaster 140785 R-DME-3000103 https://reactome.org/PathwayBrowser/#/R-DME-3000103 CUBN:AMN binds CBLIF:RCbl IEA Drosophila melanogaster 140785 R-DME-3000112 https://reactome.org/PathwayBrowser/#/R-DME-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Drosophila melanogaster 140785 R-DME-3000120 https://reactome.org/PathwayBrowser/#/R-DME-3000120 CBLIF binds RCbl IEA Drosophila melanogaster 140785 R-DME-3000122 https://reactome.org/PathwayBrowser/#/R-DME-3000122 CD320 binds extracellular TCN2:RCbl IEA Drosophila melanogaster 140785 R-DME-3000137 https://reactome.org/PathwayBrowser/#/R-DME-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome IEA Drosophila melanogaster 140785 R-DME-3095901 https://reactome.org/PathwayBrowser/#/R-DME-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Drosophila melanogaster 140785 R-DME-3132759 https://reactome.org/PathwayBrowser/#/R-DME-3132759 TCN1 binds RCbl IEA Drosophila melanogaster 140785 R-DRE-3095889 https://reactome.org/PathwayBrowser/#/R-DRE-3095889 MMACHC dealkylates RCbl IEA Danio rerio 140785 R-GGA-3000074 https://reactome.org/PathwayBrowser/#/R-GGA-3000074 TCN2 binds RCbl in the circulation IEA Gallus gallus 140785 R-GGA-3095889 https://reactome.org/PathwayBrowser/#/R-GGA-3095889 MMACHC dealkylates RCbl IEA Gallus gallus 140785 R-GGA-3095901 https://reactome.org/PathwayBrowser/#/R-GGA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Gallus gallus 140785 R-GGA-5223313 https://reactome.org/PathwayBrowser/#/R-GGA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Gallus gallus 140785 R-GGA-9759206 https://reactome.org/PathwayBrowser/#/R-GGA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Gallus gallus 140785 R-HSA-3000074 https://reactome.org/PathwayBrowser/#/R-HSA-3000074 TCN2 binds RCbl in the circulation TAS Homo sapiens 140785 R-HSA-3000103 https://reactome.org/PathwayBrowser/#/R-HSA-3000103 CUBN:AMN binds CBLIF:RCbl TAS Homo sapiens 140785 R-HSA-3000112 https://reactome.org/PathwayBrowser/#/R-HSA-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome TAS Homo sapiens 140785 R-HSA-3000120 https://reactome.org/PathwayBrowser/#/R-HSA-3000120 CBLIF binds RCbl TAS Homo sapiens 140785 R-HSA-3000122 https://reactome.org/PathwayBrowser/#/R-HSA-3000122 CD320 binds extracellular TCN2:RCbl TAS Homo sapiens 140785 R-HSA-3000137 https://reactome.org/PathwayBrowser/#/R-HSA-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome TAS Homo sapiens 140785 R-HSA-3000243 https://reactome.org/PathwayBrowser/#/R-HSA-3000243 Unknown lysosomal protease degrades CBLIF:RCbl to release Cbl TAS Homo sapiens 140785 R-HSA-3000263 https://reactome.org/PathwayBrowser/#/R-HSA-3000263 TCN2:RCbl is degraded to release RCbl TAS Homo sapiens 140785 R-HSA-3095889 https://reactome.org/PathwayBrowser/#/R-HSA-3095889 MMACHC dealkylates RCbl TAS Homo sapiens 140785 R-HSA-3095901 https://reactome.org/PathwayBrowser/#/R-HSA-3095901 ABCC1 transports cytosolic RCbl to extracellular region TAS Homo sapiens 140785 R-HSA-3132753 https://reactome.org/PathwayBrowser/#/R-HSA-3132753 Pancreatic proteases degrade TCN1:RCbl TAS Homo sapiens 140785 R-HSA-3132759 https://reactome.org/PathwayBrowser/#/R-HSA-3132759 TCN1 binds RCbl TAS Homo sapiens 140785 R-HSA-3296462 https://reactome.org/PathwayBrowser/#/R-HSA-3296462 Defective CUBN does not transport GIF:Cbl TAS Homo sapiens 140785 R-HSA-3296477 https://reactome.org/PathwayBrowser/#/R-HSA-3296477 Defective AMN does not transport GIF:Cbl TAS Homo sapiens 140785 R-HSA-5223313 https://reactome.org/PathwayBrowser/#/R-HSA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) TAS Homo sapiens 140785 R-HSA-9759202 https://reactome.org/PathwayBrowser/#/R-HSA-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome TAS Homo sapiens 140785 R-HSA-9759206 https://reactome.org/PathwayBrowser/#/R-HSA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol TAS Homo sapiens 140785 R-HSA-9759209 https://reactome.org/PathwayBrowser/#/R-HSA-9759209 LRP2 binds extracellular TCN2:RCbl TAS Homo sapiens 140785 R-MMU-3000074 https://reactome.org/PathwayBrowser/#/R-MMU-3000074 TCN2 binds RCbl in the circulation IEA Mus musculus 140785 R-MMU-3000112 https://reactome.org/PathwayBrowser/#/R-MMU-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Mus musculus 140785 R-MMU-3000120 https://reactome.org/PathwayBrowser/#/R-MMU-3000120 CBLIF binds RCbl IEA Mus musculus 140785 R-MMU-3000122 https://reactome.org/PathwayBrowser/#/R-MMU-3000122 CD320 binds extracellular TCN2:RCbl IEA Mus musculus 140785 R-MMU-3095889 https://reactome.org/PathwayBrowser/#/R-MMU-3095889 MMACHC dealkylates RCbl IEA Mus musculus 140785 R-MMU-3095901 https://reactome.org/PathwayBrowser/#/R-MMU-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Mus musculus 140785 R-MMU-5223313 https://reactome.org/PathwayBrowser/#/R-MMU-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Mus musculus 140785 R-MMU-9759202 https://reactome.org/PathwayBrowser/#/R-MMU-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Mus musculus 140785 R-MMU-9759206 https://reactome.org/PathwayBrowser/#/R-MMU-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Mus musculus 140785 R-MMU-9759209 https://reactome.org/PathwayBrowser/#/R-MMU-9759209 LRP2 binds extracellular TCN2:RCbl IEA Mus musculus 140785 R-RNO-3000074 https://reactome.org/PathwayBrowser/#/R-RNO-3000074 TCN2 binds RCbl in the circulation IEA Rattus norvegicus 140785 R-RNO-3000103 https://reactome.org/PathwayBrowser/#/R-RNO-3000103 CUBN:AMN binds CBLIF:RCbl IEA Rattus norvegicus 140785 R-RNO-3000112 https://reactome.org/PathwayBrowser/#/R-RNO-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Rattus norvegicus 140785 R-RNO-3000120 https://reactome.org/PathwayBrowser/#/R-RNO-3000120 CBLIF binds RCbl IEA Rattus norvegicus 140785 R-RNO-3000122 https://reactome.org/PathwayBrowser/#/R-RNO-3000122 CD320 binds extracellular TCN2:RCbl IEA Rattus norvegicus 140785 R-RNO-3000137 https://reactome.org/PathwayBrowser/#/R-RNO-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome IEA Rattus norvegicus 140785 R-RNO-3095889 https://reactome.org/PathwayBrowser/#/R-RNO-3095889 MMACHC dealkylates RCbl IEA Rattus norvegicus 140785 R-RNO-3095901 https://reactome.org/PathwayBrowser/#/R-RNO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Rattus norvegicus 140785 R-RNO-9759202 https://reactome.org/PathwayBrowser/#/R-RNO-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Rattus norvegicus 140785 R-RNO-9759209 https://reactome.org/PathwayBrowser/#/R-RNO-9759209 LRP2 binds extracellular TCN2:RCbl IEA Rattus norvegicus 140785 R-SCE-3095901 https://reactome.org/PathwayBrowser/#/R-SCE-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Saccharomyces cerevisiae 140785 R-SPO-3095901 https://reactome.org/PathwayBrowser/#/R-SPO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Schizosaccharomyces pombe 140785 R-SSC-3000074 https://reactome.org/PathwayBrowser/#/R-SSC-3000074 TCN2 binds RCbl in the circulation IEA Sus scrofa 140785 R-SSC-3000112 https://reactome.org/PathwayBrowser/#/R-SSC-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Sus scrofa 140785 R-SSC-3000120 https://reactome.org/PathwayBrowser/#/R-SSC-3000120 CBLIF binds RCbl IEA Sus scrofa 140785 R-SSC-3000122 https://reactome.org/PathwayBrowser/#/R-SSC-3000122 CD320 binds extracellular TCN2:RCbl IEA Sus scrofa 140785 R-SSC-3095889 https://reactome.org/PathwayBrowser/#/R-SSC-3095889 MMACHC dealkylates RCbl IEA Sus scrofa 140785 R-SSC-3095901 https://reactome.org/PathwayBrowser/#/R-SSC-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Sus scrofa 140785 R-SSC-3132753 https://reactome.org/PathwayBrowser/#/R-SSC-3132753 Pancreatic proteases degrade TCN1:RCbl IEA Sus scrofa 140785 R-SSC-3132759 https://reactome.org/PathwayBrowser/#/R-SSC-3132759 TCN1 binds RCbl IEA Sus scrofa 140785 R-SSC-5223313 https://reactome.org/PathwayBrowser/#/R-SSC-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Sus scrofa 140785 R-SSC-9759206 https://reactome.org/PathwayBrowser/#/R-SSC-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Sus scrofa 140785 R-XTR-3000074 https://reactome.org/PathwayBrowser/#/R-XTR-3000074 TCN2 binds RCbl in the circulation IEA Xenopus tropicalis 140785 R-XTR-3000120 https://reactome.org/PathwayBrowser/#/R-XTR-3000120 CBLIF binds RCbl IEA Xenopus tropicalis 140785 R-XTR-3095889 https://reactome.org/PathwayBrowser/#/R-XTR-3095889 MMACHC dealkylates RCbl IEA Xenopus tropicalis 140785 R-XTR-3095901 https://reactome.org/PathwayBrowser/#/R-XTR-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Xenopus tropicalis 140785 R-XTR-3132753 https://reactome.org/PathwayBrowser/#/R-XTR-3132753 Pancreatic proteases degrade TCN1:RCbl IEA Xenopus tropicalis 140785 R-XTR-3132759 https://reactome.org/PathwayBrowser/#/R-XTR-3132759 TCN1 binds RCbl IEA Xenopus tropicalis 140876 R-BTA-9603989 https://reactome.org/PathwayBrowser/#/R-BTA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Bos taurus 140876 R-CEL-9603989 https://reactome.org/PathwayBrowser/#/R-CEL-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Caenorhabditis elegans 140876 R-CFA-9603989 https://reactome.org/PathwayBrowser/#/R-CFA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Canis familiaris 140876 R-DME-9603989 https://reactome.org/PathwayBrowser/#/R-DME-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Drosophila melanogaster 140876 R-DRE-9603989 https://reactome.org/PathwayBrowser/#/R-DRE-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Danio rerio 140876 R-GGA-9603989 https://reactome.org/PathwayBrowser/#/R-GGA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Gallus gallus 140876 R-HSA-9603989 https://reactome.org/PathwayBrowser/#/R-HSA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain TAS Homo sapiens 140876 R-MMU-9603989 https://reactome.org/PathwayBrowser/#/R-MMU-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Mus musculus 140876 R-RNO-9603989 https://reactome.org/PathwayBrowser/#/R-RNO-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Rattus norvegicus 140876 R-SSC-9603989 https://reactome.org/PathwayBrowser/#/R-SSC-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Sus scrofa 140876 R-XTR-9603989 https://reactome.org/PathwayBrowser/#/R-XTR-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Xenopus tropicalis 140911 R-BTA-9603983 https://reactome.org/PathwayBrowser/#/R-BTA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Bos taurus 140911 R-BTA-9603984 https://reactome.org/PathwayBrowser/#/R-BTA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Bos taurus 140911 R-CEL-9603983 https://reactome.org/PathwayBrowser/#/R-CEL-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Caenorhabditis elegans 140911 R-CEL-9603984 https://reactome.org/PathwayBrowser/#/R-CEL-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Caenorhabditis elegans 140911 R-CFA-9603983 https://reactome.org/PathwayBrowser/#/R-CFA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Canis familiaris 140911 R-CFA-9603984 https://reactome.org/PathwayBrowser/#/R-CFA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Canis familiaris 140911 R-DDI-9603984 https://reactome.org/PathwayBrowser/#/R-DDI-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Dictyostelium discoideum 140911 R-DME-9603984 https://reactome.org/PathwayBrowser/#/R-DME-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Drosophila melanogaster 140911 R-DRE-9603984 https://reactome.org/PathwayBrowser/#/R-DRE-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Danio rerio 140911 R-GGA-9603984 https://reactome.org/PathwayBrowser/#/R-GGA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Gallus gallus 140911 R-HSA-9603983 https://reactome.org/PathwayBrowser/#/R-HSA-9603983 FUT2 transfers Fuc to LeX to form LeY TAS Homo sapiens 140911 R-HSA-9603984 https://reactome.org/PathwayBrowser/#/R-HSA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX TAS Homo sapiens 140911 R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 140911 R-MMU-9603983 https://reactome.org/PathwayBrowser/#/R-MMU-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Mus musculus 140911 R-MMU-9603984 https://reactome.org/PathwayBrowser/#/R-MMU-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Mus musculus 140911 R-RNO-9603983 https://reactome.org/PathwayBrowser/#/R-RNO-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Rattus norvegicus 140911 R-RNO-9603984 https://reactome.org/PathwayBrowser/#/R-RNO-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Rattus norvegicus 140911 R-SSC-9603983 https://reactome.org/PathwayBrowser/#/R-SSC-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Sus scrofa 140911 R-SSC-9603984 https://reactome.org/PathwayBrowser/#/R-SSC-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Sus scrofa 140911 R-XTR-9603983 https://reactome.org/PathwayBrowser/#/R-XTR-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Xenopus tropicalis 140911 R-XTR-9603984 https://reactome.org/PathwayBrowser/#/R-XTR-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Xenopus tropicalis 140912 R-BTA-9603983 https://reactome.org/PathwayBrowser/#/R-BTA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Bos taurus 140912 R-CEL-9603983 https://reactome.org/PathwayBrowser/#/R-CEL-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Caenorhabditis elegans 140912 R-CFA-9603983 https://reactome.org/PathwayBrowser/#/R-CFA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Canis familiaris 140912 R-HSA-9603983 https://reactome.org/PathwayBrowser/#/R-HSA-9603983 FUT2 transfers Fuc to LeX to form LeY TAS Homo sapiens 140912 R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 140912 R-MMU-9603983 https://reactome.org/PathwayBrowser/#/R-MMU-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Mus musculus 140912 R-RNO-9603983 https://reactome.org/PathwayBrowser/#/R-RNO-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Rattus norvegicus 140912 R-SSC-9603983 https://reactome.org/PathwayBrowser/#/R-SSC-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Sus scrofa 140912 R-XTR-9603983 https://reactome.org/PathwayBrowser/#/R-XTR-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Xenopus tropicalis 140915 R-BTA-9605644 https://reactome.org/PathwayBrowser/#/R-BTA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Bos taurus 140915 R-CEL-9605644 https://reactome.org/PathwayBrowser/#/R-CEL-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Caenorhabditis elegans 140915 R-CFA-9605644 https://reactome.org/PathwayBrowser/#/R-CFA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Canis familiaris 140915 R-DDI-9605644 https://reactome.org/PathwayBrowser/#/R-DDI-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Dictyostelium discoideum 140915 R-DME-9605644 https://reactome.org/PathwayBrowser/#/R-DME-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Drosophila melanogaster 140915 R-HSA-9605644 https://reactome.org/PathwayBrowser/#/R-HSA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA TAS Homo sapiens 140915 R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 140915 R-SSC-9605644 https://reactome.org/PathwayBrowser/#/R-SSC-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Sus scrofa 140915 R-XTR-9605644 https://reactome.org/PathwayBrowser/#/R-XTR-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Xenopus tropicalis 140917 R-BTA-9603987 https://reactome.org/PathwayBrowser/#/R-BTA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Bos taurus 140917 R-BTA-9603991 https://reactome.org/PathwayBrowser/#/R-BTA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Bos taurus 140917 R-BTA-9605609 https://reactome.org/PathwayBrowser/#/R-BTA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Bos taurus 140917 R-CEL-9605609 https://reactome.org/PathwayBrowser/#/R-CEL-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Caenorhabditis elegans 140917 R-CFA-9603987 https://reactome.org/PathwayBrowser/#/R-CFA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Canis familiaris 140917 R-CFA-9603991 https://reactome.org/PathwayBrowser/#/R-CFA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Canis familiaris 140917 R-CFA-9605609 https://reactome.org/PathwayBrowser/#/R-CFA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Canis familiaris 140917 R-DDI-9605609 https://reactome.org/PathwayBrowser/#/R-DDI-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Dictyostelium discoideum 140917 R-DME-9605609 https://reactome.org/PathwayBrowser/#/R-DME-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Drosophila melanogaster 140917 R-GGA-9603987 https://reactome.org/PathwayBrowser/#/R-GGA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Gallus gallus 140917 R-GGA-9603991 https://reactome.org/PathwayBrowser/#/R-GGA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Gallus gallus 140917 R-HSA-9603987 https://reactome.org/PathwayBrowser/#/R-HSA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG TAS Homo sapiens 140917 R-HSA-9603991 https://reactome.org/PathwayBrowser/#/R-HSA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG TAS Homo sapiens 140917 R-HSA-9605609 https://reactome.org/PathwayBrowser/#/R-HSA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA TAS Homo sapiens 140917 R-MMU-9603987 https://reactome.org/PathwayBrowser/#/R-MMU-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Mus musculus 140917 R-MMU-9603991 https://reactome.org/PathwayBrowser/#/R-MMU-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Mus musculus 140917 R-RNO-9603987 https://reactome.org/PathwayBrowser/#/R-RNO-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Rattus norvegicus 140917 R-RNO-9603991 https://reactome.org/PathwayBrowser/#/R-RNO-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Rattus norvegicus 140917 R-SSC-9603987 https://reactome.org/PathwayBrowser/#/R-SSC-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Sus scrofa 140917 R-SSC-9603991 https://reactome.org/PathwayBrowser/#/R-SSC-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Sus scrofa 140917 R-SSC-9605609 https://reactome.org/PathwayBrowser/#/R-SSC-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Sus scrofa 140917 R-XTR-9603987 https://reactome.org/PathwayBrowser/#/R-XTR-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Xenopus tropicalis 140917 R-XTR-9603991 https://reactome.org/PathwayBrowser/#/R-XTR-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Xenopus tropicalis 140917 R-XTR-9605609 https://reactome.org/PathwayBrowser/#/R-XTR-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Xenopus tropicalis 140918 R-BTA-9605600 https://reactome.org/PathwayBrowser/#/R-BTA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Bos taurus 140918 R-BTA-9605682 https://reactome.org/PathwayBrowser/#/R-BTA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Bos taurus 140918 R-BTA-9605700 https://reactome.org/PathwayBrowser/#/R-BTA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Bos taurus 140918 R-CEL-9605682 https://reactome.org/PathwayBrowser/#/R-CEL-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Caenorhabditis elegans 140918 R-CFA-9605600 https://reactome.org/PathwayBrowser/#/R-CFA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Canis familiaris 140918 R-CFA-9605682 https://reactome.org/PathwayBrowser/#/R-CFA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Canis familiaris 140918 R-CFA-9605700 https://reactome.org/PathwayBrowser/#/R-CFA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Canis familiaris 140918 R-DDI-9605682 https://reactome.org/PathwayBrowser/#/R-DDI-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Dictyostelium discoideum 140918 R-DME-9605682 https://reactome.org/PathwayBrowser/#/R-DME-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Drosophila melanogaster 140918 R-DRE-9605600 https://reactome.org/PathwayBrowser/#/R-DRE-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Danio rerio 140918 R-DRE-9605682 https://reactome.org/PathwayBrowser/#/R-DRE-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Danio rerio 140918 R-GGA-9605600 https://reactome.org/PathwayBrowser/#/R-GGA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Gallus gallus 140918 R-GGA-9605682 https://reactome.org/PathwayBrowser/#/R-GGA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Gallus gallus 140918 R-HSA-9605600 https://reactome.org/PathwayBrowser/#/R-HSA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG TAS Homo sapiens 140918 R-HSA-9605682 https://reactome.org/PathwayBrowser/#/R-HSA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX TAS Homo sapiens 140918 R-HSA-9605700 https://reactome.org/PathwayBrowser/#/R-HSA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda TAS Homo sapiens 140918 R-MMU-9605600 https://reactome.org/PathwayBrowser/#/R-MMU-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Mus musculus 140918 R-MMU-9605682 https://reactome.org/PathwayBrowser/#/R-MMU-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Mus musculus 140918 R-MMU-9605700 https://reactome.org/PathwayBrowser/#/R-MMU-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Mus musculus 140918 R-RNO-9605600 https://reactome.org/PathwayBrowser/#/R-RNO-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Rattus norvegicus 140918 R-RNO-9605682 https://reactome.org/PathwayBrowser/#/R-RNO-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Rattus norvegicus 140918 R-RNO-9605700 https://reactome.org/PathwayBrowser/#/R-RNO-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Rattus norvegicus 140918 R-SSC-9605600 https://reactome.org/PathwayBrowser/#/R-SSC-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Sus scrofa 140918 R-SSC-9605682 https://reactome.org/PathwayBrowser/#/R-SSC-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Sus scrofa 140918 R-SSC-9605700 https://reactome.org/PathwayBrowser/#/R-SSC-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Sus scrofa 140918 R-XTR-9605600 https://reactome.org/PathwayBrowser/#/R-XTR-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Xenopus tropicalis 140918 R-XTR-9605682 https://reactome.org/PathwayBrowser/#/R-XTR-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Xenopus tropicalis 140918 R-XTR-9605700 https://reactome.org/PathwayBrowser/#/R-XTR-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Xenopus tropicalis 140919 R-BTA-9603991 https://reactome.org/PathwayBrowser/#/R-BTA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Bos taurus 140919 R-BTA-9605644 https://reactome.org/PathwayBrowser/#/R-BTA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Bos taurus 140919 R-CEL-9605644 https://reactome.org/PathwayBrowser/#/R-CEL-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Caenorhabditis elegans 140919 R-CFA-9603991 https://reactome.org/PathwayBrowser/#/R-CFA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Canis familiaris 140919 R-CFA-9605644 https://reactome.org/PathwayBrowser/#/R-CFA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Canis familiaris 140919 R-DDI-9605644 https://reactome.org/PathwayBrowser/#/R-DDI-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Dictyostelium discoideum 140919 R-DME-9605644 https://reactome.org/PathwayBrowser/#/R-DME-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Drosophila melanogaster 140919 R-GGA-9603991 https://reactome.org/PathwayBrowser/#/R-GGA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Gallus gallus 140919 R-HSA-9603991 https://reactome.org/PathwayBrowser/#/R-HSA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG TAS Homo sapiens 140919 R-HSA-9605644 https://reactome.org/PathwayBrowser/#/R-HSA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA TAS Homo sapiens 140919 R-MMU-9603991 https://reactome.org/PathwayBrowser/#/R-MMU-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Mus musculus 140919 R-RNO-9603991 https://reactome.org/PathwayBrowser/#/R-RNO-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Rattus norvegicus 140919 R-SSC-9603991 https://reactome.org/PathwayBrowser/#/R-SSC-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Sus scrofa 140919 R-SSC-9605644 https://reactome.org/PathwayBrowser/#/R-SSC-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Sus scrofa 140919 R-XTR-9603991 https://reactome.org/PathwayBrowser/#/R-XTR-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Xenopus tropicalis 140919 R-XTR-9605644 https://reactome.org/PathwayBrowser/#/R-XTR-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Xenopus tropicalis 141346 R-BTA-9611839 https://reactome.org/PathwayBrowser/#/R-BTA-9611839 β3-agonists bind ADRB3 IEA Bos taurus 141346 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 141346 R-CFA-9611839 https://reactome.org/PathwayBrowser/#/R-CFA-9611839 β3-agonists bind ADRB3 IEA Canis familiaris 141346 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 141346 R-DME-9611839 https://reactome.org/PathwayBrowser/#/R-DME-9611839 β3-agonists bind ADRB3 IEA Drosophila melanogaster 141346 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 141346 R-GGA-9611839 https://reactome.org/PathwayBrowser/#/R-GGA-9611839 β3-agonists bind ADRB3 IEA Gallus gallus 141346 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 141346 R-HSA-9611839 https://reactome.org/PathwayBrowser/#/R-HSA-9611839 β3-agonists bind ADRB3 TAS Homo sapiens 141346 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 141346 R-MMU-9611839 https://reactome.org/PathwayBrowser/#/R-MMU-9611839 β3-agonists bind ADRB3 IEA Mus musculus 141346 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 141346 R-RNO-9611839 https://reactome.org/PathwayBrowser/#/R-RNO-9611839 β3-agonists bind ADRB3 IEA Rattus norvegicus 141346 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 141346 R-SSC-9611839 https://reactome.org/PathwayBrowser/#/R-SSC-9611839 β3-agonists bind ADRB3 IEA Sus scrofa 141346 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 141499 R-BTA-71241 https://reactome.org/PathwayBrowser/#/R-BTA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Bos taurus 141499 R-BTA-71249 https://reactome.org/PathwayBrowser/#/R-BTA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Bos taurus 141499 R-CEL-71241 https://reactome.org/PathwayBrowser/#/R-CEL-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Caenorhabditis elegans 141499 R-CEL-71249 https://reactome.org/PathwayBrowser/#/R-CEL-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Caenorhabditis elegans 141499 R-CFA-71241 https://reactome.org/PathwayBrowser/#/R-CFA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Canis familiaris 141499 R-CFA-71249 https://reactome.org/PathwayBrowser/#/R-CFA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Canis familiaris 141499 R-DDI-71249 https://reactome.org/PathwayBrowser/#/R-DDI-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Dictyostelium discoideum 141499 R-DME-71241 https://reactome.org/PathwayBrowser/#/R-DME-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Drosophila melanogaster 141499 R-DME-71249 https://reactome.org/PathwayBrowser/#/R-DME-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Drosophila melanogaster 141499 R-DRE-71249 https://reactome.org/PathwayBrowser/#/R-DRE-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Danio rerio 141499 R-GGA-71241 https://reactome.org/PathwayBrowser/#/R-GGA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Gallus gallus 141499 R-GGA-71249 https://reactome.org/PathwayBrowser/#/R-GGA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Gallus gallus 141499 R-HSA-71241 https://reactome.org/PathwayBrowser/#/R-HSA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA TAS Homo sapiens 141499 R-HSA-71249 https://reactome.org/PathwayBrowser/#/R-HSA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly TAS Homo sapiens 141499 R-HSA-8949413 https://reactome.org/PathwayBrowser/#/R-HSA-8949413 HTMLYS translocates from the mitochondrial matrix to the cytosol TAS Homo sapiens 141499 R-MMU-71241 https://reactome.org/PathwayBrowser/#/R-MMU-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Mus musculus 141499 R-MMU-71249 https://reactome.org/PathwayBrowser/#/R-MMU-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Mus musculus 141499 R-PFA-71249 https://reactome.org/PathwayBrowser/#/R-PFA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Plasmodium falciparum 141499 R-RNO-71241 https://reactome.org/PathwayBrowser/#/R-RNO-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Rattus norvegicus 141499 R-RNO-71249 https://reactome.org/PathwayBrowser/#/R-RNO-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Rattus norvegicus 141499 R-SSC-71241 https://reactome.org/PathwayBrowser/#/R-SSC-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Sus scrofa 141499 R-SSC-71249 https://reactome.org/PathwayBrowser/#/R-SSC-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Sus scrofa 141499 R-XTR-71241 https://reactome.org/PathwayBrowser/#/R-XTR-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Xenopus tropicalis 141499 R-XTR-71249 https://reactome.org/PathwayBrowser/#/R-XTR-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Xenopus tropicalis 141520 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 141520 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 141520 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 141520 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 141520 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 141520 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 141520 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 141520 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 141520 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 141520 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 141520 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 141520 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 141520 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 141520 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 141520 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 141520 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 141520 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 141520 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 141520 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 141520 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 141520 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 141520 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 141520 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 141520 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 141520 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 141520 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 141520 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 141520 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 141520 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 141520 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 141520 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 141520 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 141520 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 141521 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 141521 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 141521 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 141521 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 141521 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 141521 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 141521 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 141521 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 141521 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 141521 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 141521 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 141521 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 141521 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 141521 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 141521 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 141521 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 141521 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 141521 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 141521 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 141521 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 141521 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 141521 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 141521 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 141521 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 141521 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 141521 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 141521 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 141521 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 141521 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 141521 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 141521 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 141521 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 141521 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 141522 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 141522 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 141522 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 141522 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 141522 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 141522 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 141522 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 141522 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 141522 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 141522 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 141522 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 141522 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 141522 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 141522 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 141522 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 141522 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 141522 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 141522 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 141522 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 141522 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 141522 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 141522 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 141522 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 141522 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 141522 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 141522 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 141522 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 141522 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 141522 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 141522 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 141522 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 141522 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 141522 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 141552 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(34-41) binds to AGTR1 IEA Bos taurus 141552 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGRT1 IEA Bos taurus 141552 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(34-41) binds to AGTR1 IEA Caenorhabditis elegans 141552 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGRT1 IEA Caenorhabditis elegans 141552 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(34-41) binds to AGTR1 IEA Canis familiaris 141552 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGRT1 IEA Canis familiaris 141552 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(34-41) binds to AGTR1 IEA Drosophila melanogaster 141552 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGRT1 IEA Drosophila melanogaster 141552 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(34-41) binds to AGTR1 IEA Danio rerio 141552 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGRT1 IEA Danio rerio 141552 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(34-41) binds to AGTR1 IEA Gallus gallus 141552 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGRT1 IEA Gallus gallus 141552 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(34-41) binds to AGTR1 TAS Homo sapiens 141552 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGRT1 TAS Homo sapiens 141552 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(34-41) binds to AGTR1 IEA Mus musculus 141552 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGRT1 IEA Mus musculus 141552 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(34-41) binds to AGTR1 IEA Rattus norvegicus 141552 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGRT1 IEA Rattus norvegicus 141552 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(34-41) binds to AGTR1 IEA Sus scrofa 141552 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGRT1 IEA Sus scrofa 141634 R-HSA-1500761 https://reactome.org/PathwayBrowser/#/R-HSA-1500761 Nitrogen dioxide is reduced to NO by F420 TAS Homo sapiens 141634 R-HSA-1500781 https://reactome.org/PathwayBrowser/#/R-HSA-1500781 Fgd1 reactivates F420 TAS Homo sapiens 141635 R-HSA-1500761 https://reactome.org/PathwayBrowser/#/R-HSA-1500761 Nitrogen dioxide is reduced to NO by F420 TAS Homo sapiens 141635 R-HSA-1500781 https://reactome.org/PathwayBrowser/#/R-HSA-1500781 Fgd1 reactivates F420 TAS Homo sapiens 141969 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 141969 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 141969 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 141969 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 141969 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 141969 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 141969 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 141969 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 141969 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 141969 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 141969 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 141969 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 141969 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 141969 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 141969 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 141969 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 141969 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 141969 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 141969 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 141969 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 141969 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 142077 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 142077 R-BTA-9611751 https://reactome.org/PathwayBrowser/#/R-BTA-9611751 β1,2-agonists bind ADRB1,2 IEA Bos taurus 142077 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 142077 R-CFA-9611751 https://reactome.org/PathwayBrowser/#/R-CFA-9611751 β1,2-agonists bind ADRB1,2 IEA Canis familiaris 142077 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 142077 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 142077 R-DME-9611751 https://reactome.org/PathwayBrowser/#/R-DME-9611751 β1,2-agonists bind ADRB1,2 IEA Drosophila melanogaster 142077 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 142077 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 142077 R-DRE-9611751 https://reactome.org/PathwayBrowser/#/R-DRE-9611751 β1,2-agonists bind ADRB1,2 IEA Danio rerio 142077 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 142077 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 142077 R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus 142077 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 142077 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 142077 R-HSA-9611751 https://reactome.org/PathwayBrowser/#/R-HSA-9611751 β1,2-agonists bind ADRB1,2 TAS Homo sapiens 142077 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 142077 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 142077 R-MMU-9611751 https://reactome.org/PathwayBrowser/#/R-MMU-9611751 β1,2-agonists bind ADRB1,2 IEA Mus musculus 142077 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 142077 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 142077 R-RNO-9611751 https://reactome.org/PathwayBrowser/#/R-RNO-9611751 β1,2-agonists bind ADRB1,2 IEA Rattus norvegicus 142077 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 142077 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 142077 R-SSC-9611751 https://reactome.org/PathwayBrowser/#/R-SSC-9611751 β1,2-agonists bind ADRB1,2 IEA Sus scrofa 142077 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 142077 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 142077 R-XTR-9611751 https://reactome.org/PathwayBrowser/#/R-XTR-9611751 β1,2-agonists bind ADRB1,2 IEA Xenopus tropicalis 142077 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 142418 R-BTA-9611839 https://reactome.org/PathwayBrowser/#/R-BTA-9611839 β3-agonists bind ADRB3 IEA Bos taurus 142418 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 142418 R-CFA-9611839 https://reactome.org/PathwayBrowser/#/R-CFA-9611839 β3-agonists bind ADRB3 IEA Canis familiaris 142418 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 142418 R-DME-9611839 https://reactome.org/PathwayBrowser/#/R-DME-9611839 β3-agonists bind ADRB3 IEA Drosophila melanogaster 142418 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 142418 R-GGA-9611839 https://reactome.org/PathwayBrowser/#/R-GGA-9611839 β3-agonists bind ADRB3 IEA Gallus gallus 142418 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 142418 R-HSA-9611839 https://reactome.org/PathwayBrowser/#/R-HSA-9611839 β3-agonists bind ADRB3 TAS Homo sapiens 142418 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 142418 R-MMU-9611839 https://reactome.org/PathwayBrowser/#/R-MMU-9611839 β3-agonists bind ADRB3 IEA Mus musculus 142418 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 142418 R-RNO-9611839 https://reactome.org/PathwayBrowser/#/R-RNO-9611839 β3-agonists bind ADRB3 IEA Rattus norvegicus 142418 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 142418 R-SSC-9611839 https://reactome.org/PathwayBrowser/#/R-SSC-9611839 β3-agonists bind ADRB3 IEA Sus scrofa 142418 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 142430 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 142430 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 142430 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 142430 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 142430 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 142430 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 142430 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 142430 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 142430 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 142430 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 142431 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 142431 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 142431 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 142431 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 142431 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 142431 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 142431 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 142431 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 142431 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 142431 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 142432 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 142432 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 142432 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 142432 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 142432 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 142432 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 142432 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 142432 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 142432 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 142432 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 142433 R-BTA-9621179 https://reactome.org/PathwayBrowser/#/R-BTA-9621179 Cinaciguat binds sGC:NO IEA Bos taurus 142433 R-CFA-9621179 https://reactome.org/PathwayBrowser/#/R-CFA-9621179 Cinaciguat binds sGC:NO IEA Canis familiaris 142433 R-DME-9621179 https://reactome.org/PathwayBrowser/#/R-DME-9621179 Cinaciguat binds sGC:NO IEA Drosophila melanogaster 142433 R-DRE-9621179 https://reactome.org/PathwayBrowser/#/R-DRE-9621179 Cinaciguat binds sGC:NO IEA Danio rerio 142433 R-GGA-9621179 https://reactome.org/PathwayBrowser/#/R-GGA-9621179 Cinaciguat binds sGC:NO IEA Gallus gallus 142433 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 142433 R-HSA-9621179 https://reactome.org/PathwayBrowser/#/R-HSA-9621179 Cinaciguat binds sGC:NO TAS Homo sapiens 142433 R-MMU-9621179 https://reactome.org/PathwayBrowser/#/R-MMU-9621179 Cinaciguat binds sGC:NO IEA Mus musculus 142433 R-RNO-9621179 https://reactome.org/PathwayBrowser/#/R-RNO-9621179 Cinaciguat binds sGC:NO IEA Rattus norvegicus 142433 R-SSC-9621179 https://reactome.org/PathwayBrowser/#/R-SSC-9621179 Cinaciguat binds sGC:NO IEA Sus scrofa 142435 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 142435 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 142435 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 142435 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 142435 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 142435 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 142435 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 142435 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 142435 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 142435 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 142437 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 142437 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 142437 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 142437 R-BTA-9603302 https://reactome.org/PathwayBrowser/#/R-BTA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Bos taurus 142437 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 142437 R-CFA-9603302 https://reactome.org/PathwayBrowser/#/R-CFA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Canis familiaris 142437 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 142437 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 142437 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 142437 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 142437 R-GGA-9603302 https://reactome.org/PathwayBrowser/#/R-GGA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Gallus gallus 142437 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 142437 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 142437 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 142437 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 142437 R-HSA-9603302 https://reactome.org/PathwayBrowser/#/R-HSA-9603302 Factor IIa inhibitors (peptide) binds IIa TAS Homo sapiens 142437 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 142437 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 142437 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 142437 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 142437 R-MMU-9603302 https://reactome.org/PathwayBrowser/#/R-MMU-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Mus musculus 142437 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 142437 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 142437 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 142437 R-RNO-9603302 https://reactome.org/PathwayBrowser/#/R-RNO-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Rattus norvegicus 142437 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 142437 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 142437 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 142437 R-SSC-9603302 https://reactome.org/PathwayBrowser/#/R-SSC-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Sus scrofa 142437 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 142437 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 142437 R-XTR-9603302 https://reactome.org/PathwayBrowser/#/R-XTR-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Xenopus tropicalis 142452 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 142452 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 142452 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 142452 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 142452 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 142452 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 142452 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 142452 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 142452 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 142452 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 142452 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 142452 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 142452 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 142452 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 142452 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 142452 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 142452 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 142452 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 142452 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 142452 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 142452 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 142452 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 142614 R-BTA-9629216 https://reactome.org/PathwayBrowser/#/R-BTA-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Bos taurus 142614 R-BTA-9629470 https://reactome.org/PathwayBrowser/#/R-BTA-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Bos taurus 142614 R-CFA-9629216 https://reactome.org/PathwayBrowser/#/R-CFA-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Canis familiaris 142614 R-CFA-9629470 https://reactome.org/PathwayBrowser/#/R-CFA-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Canis familiaris 142614 R-GGA-9629470 https://reactome.org/PathwayBrowser/#/R-GGA-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Gallus gallus 142614 R-HSA-9629216 https://reactome.org/PathwayBrowser/#/R-HSA-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA TAS Homo sapiens 142614 R-HSA-9629470 https://reactome.org/PathwayBrowser/#/R-HSA-9629470 NEIL3 cleaves 5-guanidinohydantoin TAS Homo sapiens 142614 R-MMU-9629216 https://reactome.org/PathwayBrowser/#/R-MMU-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Mus musculus 142614 R-MMU-9629470 https://reactome.org/PathwayBrowser/#/R-MMU-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Mus musculus 142614 R-RNO-9629216 https://reactome.org/PathwayBrowser/#/R-RNO-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Rattus norvegicus 142614 R-RNO-9629470 https://reactome.org/PathwayBrowser/#/R-RNO-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Rattus norvegicus 142614 R-SSC-9629216 https://reactome.org/PathwayBrowser/#/R-SSC-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Sus scrofa 142614 R-SSC-9629470 https://reactome.org/PathwayBrowser/#/R-SSC-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Sus scrofa 142614 R-XTR-9629216 https://reactome.org/PathwayBrowser/#/R-XTR-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Xenopus tropicalis 142614 R-XTR-9629470 https://reactome.org/PathwayBrowser/#/R-XTR-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Xenopus tropicalis 142623 R-BTA-9629492 https://reactome.org/PathwayBrowser/#/R-BTA-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Bos taurus 142623 R-CFA-9629492 https://reactome.org/PathwayBrowser/#/R-CFA-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Canis familiaris 142623 R-GGA-9629492 https://reactome.org/PathwayBrowser/#/R-GGA-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Gallus gallus 142623 R-HSA-9629483 https://reactome.org/PathwayBrowser/#/R-HSA-9629483 NEIL3 cleaves spiroiminodihydantoin from damaged telomeric DNA IEA Homo sapiens 142623 R-HSA-9629492 https://reactome.org/PathwayBrowser/#/R-HSA-9629492 NEIL3 cleaves spiroiminodihydantoin TAS Homo sapiens 142623 R-MMU-9629485 https://reactome.org/PathwayBrowser/#/R-MMU-9629485 Neil3 cleaves spirominodihydantoin from telomeric DNA oligomer TAS Mus musculus 142623 R-MMU-9629492 https://reactome.org/PathwayBrowser/#/R-MMU-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Mus musculus 142623 R-RNO-9629492 https://reactome.org/PathwayBrowser/#/R-RNO-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Rattus norvegicus 142623 R-SSC-9629492 https://reactome.org/PathwayBrowser/#/R-SSC-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Sus scrofa 142623 R-XTR-9629492 https://reactome.org/PathwayBrowser/#/R-XTR-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Xenopus tropicalis 142773 R-BTA-9008258 https://reactome.org/PathwayBrowser/#/R-BTA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Bos taurus 142773 R-BTA-9008270 https://reactome.org/PathwayBrowser/#/R-BTA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Bos taurus 142773 R-BTA-9008271 https://reactome.org/PathwayBrowser/#/R-BTA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Bos taurus 142773 R-BTA-9008285 https://reactome.org/PathwayBrowser/#/R-BTA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Bos taurus 142773 R-BTA-9009526 https://reactome.org/PathwayBrowser/#/R-BTA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 142773 R-BTA-9009533 https://reactome.org/PathwayBrowser/#/R-BTA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Bos taurus 142773 R-BTA-9009536 https://reactome.org/PathwayBrowser/#/R-BTA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Bos taurus 142773 R-BTA-9009541 https://reactome.org/PathwayBrowser/#/R-BTA-9009541 ESR1 binds to TFF1 gene promoter IEA Bos taurus 142773 R-BTA-9023860 https://reactome.org/PathwayBrowser/#/R-BTA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Bos taurus 142773 R-BTA-9023861 https://reactome.org/PathwayBrowser/#/R-BTA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 142773 R-BTA-9023884 https://reactome.org/PathwayBrowser/#/R-BTA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Bos taurus 142773 R-CFA-9008258 https://reactome.org/PathwayBrowser/#/R-CFA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Canis familiaris 142773 R-CFA-9008270 https://reactome.org/PathwayBrowser/#/R-CFA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Canis familiaris 142773 R-CFA-9008271 https://reactome.org/PathwayBrowser/#/R-CFA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Canis familiaris 142773 R-CFA-9008285 https://reactome.org/PathwayBrowser/#/R-CFA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Canis familiaris 142773 R-CFA-9009526 https://reactome.org/PathwayBrowser/#/R-CFA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 142773 R-CFA-9009533 https://reactome.org/PathwayBrowser/#/R-CFA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Canis familiaris 142773 R-CFA-9009536 https://reactome.org/PathwayBrowser/#/R-CFA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Canis familiaris 142773 R-CFA-9009541 https://reactome.org/PathwayBrowser/#/R-CFA-9009541 ESR1 binds to TFF1 gene promoter IEA Canis familiaris 142773 R-CFA-9023860 https://reactome.org/PathwayBrowser/#/R-CFA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Canis familiaris 142773 R-CFA-9023861 https://reactome.org/PathwayBrowser/#/R-CFA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 142773 R-CFA-9023884 https://reactome.org/PathwayBrowser/#/R-CFA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Canis familiaris 142773 R-DDI-9023860 https://reactome.org/PathwayBrowser/#/R-DDI-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Dictyostelium discoideum 142773 R-DME-9008258 https://reactome.org/PathwayBrowser/#/R-DME-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Drosophila melanogaster 142773 R-DME-9008270 https://reactome.org/PathwayBrowser/#/R-DME-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Drosophila melanogaster 142773 R-DME-9008285 https://reactome.org/PathwayBrowser/#/R-DME-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Drosophila melanogaster 142773 R-DME-9009526 https://reactome.org/PathwayBrowser/#/R-DME-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 142773 R-DME-9009533 https://reactome.org/PathwayBrowser/#/R-DME-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Drosophila melanogaster 142773 R-DME-9009536 https://reactome.org/PathwayBrowser/#/R-DME-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Drosophila melanogaster 142773 R-DME-9009541 https://reactome.org/PathwayBrowser/#/R-DME-9009541 ESR1 binds to TFF1 gene promoter IEA Drosophila melanogaster 142773 R-DME-9023860 https://reactome.org/PathwayBrowser/#/R-DME-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Drosophila melanogaster 142773 R-DME-9023861 https://reactome.org/PathwayBrowser/#/R-DME-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 142773 R-DME-9023884 https://reactome.org/PathwayBrowser/#/R-DME-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Drosophila melanogaster 142773 R-DRE-9009526 https://reactome.org/PathwayBrowser/#/R-DRE-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Danio rerio 142773 R-DRE-9009533 https://reactome.org/PathwayBrowser/#/R-DRE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Danio rerio 142773 R-DRE-9009541 https://reactome.org/PathwayBrowser/#/R-DRE-9009541 ESR1 binds to TFF1 gene promoter IEA Danio rerio 142773 R-DRE-9023860 https://reactome.org/PathwayBrowser/#/R-DRE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Danio rerio 142773 R-GGA-9008258 https://reactome.org/PathwayBrowser/#/R-GGA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Gallus gallus 142773 R-GGA-9008270 https://reactome.org/PathwayBrowser/#/R-GGA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Gallus gallus 142773 R-GGA-9008285 https://reactome.org/PathwayBrowser/#/R-GGA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Gallus gallus 142773 R-GGA-9009533 https://reactome.org/PathwayBrowser/#/R-GGA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Gallus gallus 142773 R-GGA-9009536 https://reactome.org/PathwayBrowser/#/R-GGA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Gallus gallus 142773 R-GGA-9009541 https://reactome.org/PathwayBrowser/#/R-GGA-9009541 ESR1 binds to TFF1 gene promoter IEA Gallus gallus 142773 R-GGA-9023860 https://reactome.org/PathwayBrowser/#/R-GGA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Gallus gallus 142773 R-GGA-9023884 https://reactome.org/PathwayBrowser/#/R-GGA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Gallus gallus 142773 R-HSA-9008258 https://reactome.org/PathwayBrowser/#/R-HSA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene TAS Homo sapiens 142773 R-HSA-9008267 https://reactome.org/PathwayBrowser/#/R-HSA-9008267 ESR1 binds to TGFA gene promoter TAS Homo sapiens 142773 R-HSA-9008270 https://reactome.org/PathwayBrowser/#/R-HSA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene TAS Homo sapiens 142773 R-HSA-9008271 https://reactome.org/PathwayBrowser/#/R-HSA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter TAS Homo sapiens 142773 R-HSA-9008285 https://reactome.org/PathwayBrowser/#/R-HSA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 TAS Homo sapiens 142773 R-HSA-9008315 https://reactome.org/PathwayBrowser/#/R-HSA-9008315 TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen TAS Homo sapiens 142773 R-HSA-9009526 https://reactome.org/PathwayBrowser/#/R-HSA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 142773 R-HSA-9009533 https://reactome.org/PathwayBrowser/#/R-HSA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter TAS Homo sapiens 142773 R-HSA-9009536 https://reactome.org/PathwayBrowser/#/R-HSA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter TAS Homo sapiens 142773 R-HSA-9009541 https://reactome.org/PathwayBrowser/#/R-HSA-9009541 ESR1 binds to TFF1 gene promoter TAS Homo sapiens 142773 R-HSA-9023859 https://reactome.org/PathwayBrowser/#/R-HSA-9023859 Estrogen-responsive TFF1 gene expression TAS Homo sapiens 142773 R-HSA-9023860 https://reactome.org/PathwayBrowser/#/R-HSA-9023860 Histone acetyltransferases are recruited to the TFF1 gene TAS Homo sapiens 142773 R-HSA-9023861 https://reactome.org/PathwayBrowser/#/R-HSA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 142773 R-HSA-9023884 https://reactome.org/PathwayBrowser/#/R-HSA-9023884 NCOA1 recruits EP300 to TGFA promoter TAS Homo sapiens 142773 R-MMU-9008258 https://reactome.org/PathwayBrowser/#/R-MMU-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Mus musculus 142773 R-MMU-9008270 https://reactome.org/PathwayBrowser/#/R-MMU-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Mus musculus 142773 R-MMU-9008271 https://reactome.org/PathwayBrowser/#/R-MMU-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Mus musculus 142773 R-MMU-9008285 https://reactome.org/PathwayBrowser/#/R-MMU-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Mus musculus 142773 R-MMU-9009526 https://reactome.org/PathwayBrowser/#/R-MMU-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 142773 R-MMU-9009533 https://reactome.org/PathwayBrowser/#/R-MMU-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Mus musculus 142773 R-MMU-9009536 https://reactome.org/PathwayBrowser/#/R-MMU-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Mus musculus 142773 R-MMU-9009541 https://reactome.org/PathwayBrowser/#/R-MMU-9009541 ESR1 binds to TFF1 gene promoter IEA Mus musculus 142773 R-MMU-9023860 https://reactome.org/PathwayBrowser/#/R-MMU-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Mus musculus 142773 R-MMU-9023861 https://reactome.org/PathwayBrowser/#/R-MMU-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 142773 R-MMU-9023884 https://reactome.org/PathwayBrowser/#/R-MMU-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Mus musculus 142773 R-RNO-9008258 https://reactome.org/PathwayBrowser/#/R-RNO-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Rattus norvegicus 142773 R-RNO-9008270 https://reactome.org/PathwayBrowser/#/R-RNO-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Rattus norvegicus 142773 R-RNO-9008271 https://reactome.org/PathwayBrowser/#/R-RNO-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Rattus norvegicus 142773 R-RNO-9008285 https://reactome.org/PathwayBrowser/#/R-RNO-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Rattus norvegicus 142773 R-RNO-9009526 https://reactome.org/PathwayBrowser/#/R-RNO-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 142773 R-RNO-9009533 https://reactome.org/PathwayBrowser/#/R-RNO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Rattus norvegicus 142773 R-RNO-9009536 https://reactome.org/PathwayBrowser/#/R-RNO-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Rattus norvegicus 142773 R-RNO-9009541 https://reactome.org/PathwayBrowser/#/R-RNO-9009541 ESR1 binds to TFF1 gene promoter IEA Rattus norvegicus 142773 R-RNO-9023860 https://reactome.org/PathwayBrowser/#/R-RNO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Rattus norvegicus 142773 R-RNO-9023861 https://reactome.org/PathwayBrowser/#/R-RNO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 142773 R-RNO-9023884 https://reactome.org/PathwayBrowser/#/R-RNO-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Rattus norvegicus 142773 R-SCE-9009533 https://reactome.org/PathwayBrowser/#/R-SCE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Saccharomyces cerevisiae 142773 R-SCE-9023860 https://reactome.org/PathwayBrowser/#/R-SCE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Saccharomyces cerevisiae 142773 R-SCE-9023861 https://reactome.org/PathwayBrowser/#/R-SCE-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Saccharomyces cerevisiae 142773 R-SPO-9009533 https://reactome.org/PathwayBrowser/#/R-SPO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Schizosaccharomyces pombe 142773 R-SPO-9023860 https://reactome.org/PathwayBrowser/#/R-SPO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Schizosaccharomyces pombe 142773 R-SPO-9023861 https://reactome.org/PathwayBrowser/#/R-SPO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Schizosaccharomyces pombe 142773 R-SSC-9008258 https://reactome.org/PathwayBrowser/#/R-SSC-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Sus scrofa 142773 R-SSC-9008270 https://reactome.org/PathwayBrowser/#/R-SSC-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Sus scrofa 142773 R-SSC-9008271 https://reactome.org/PathwayBrowser/#/R-SSC-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Sus scrofa 142773 R-SSC-9008285 https://reactome.org/PathwayBrowser/#/R-SSC-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Sus scrofa 142773 R-SSC-9009526 https://reactome.org/PathwayBrowser/#/R-SSC-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 142773 R-SSC-9009536 https://reactome.org/PathwayBrowser/#/R-SSC-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Sus scrofa 142773 R-SSC-9009541 https://reactome.org/PathwayBrowser/#/R-SSC-9009541 ESR1 binds to TFF1 gene promoter IEA Sus scrofa 142773 R-SSC-9023860 https://reactome.org/PathwayBrowser/#/R-SSC-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Sus scrofa 142773 R-SSC-9023861 https://reactome.org/PathwayBrowser/#/R-SSC-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 142773 R-SSC-9023884 https://reactome.org/PathwayBrowser/#/R-SSC-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Sus scrofa 142773 R-XTR-9008258 https://reactome.org/PathwayBrowser/#/R-XTR-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Xenopus tropicalis 142773 R-XTR-9008285 https://reactome.org/PathwayBrowser/#/R-XTR-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Xenopus tropicalis 142773 R-XTR-9023860 https://reactome.org/PathwayBrowser/#/R-XTR-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Xenopus tropicalis 142774 R-HSA-6788974 https://reactome.org/PathwayBrowser/#/R-HSA-6788974 Hypochlorous acid and nitrite react to nitryl chloride (NO2Cl) TAS Homo sapiens 142774 R-HSA-6789185 https://reactome.org/PathwayBrowser/#/R-HSA-6789185 Chloride ion and N-acyl group react to chloramide TAS Homo sapiens 142774 R-HSA-6789218 https://reactome.org/PathwayBrowser/#/R-HSA-6789218 Hypochlorous acid (HOCl) reacts with unsaturated lipid to form lipid chlorohydrins TAS Homo sapiens 142968 R-HSA-9697064 https://reactome.org/PathwayBrowser/#/R-HSA-9697064 lprG binds to LAM,LM TAS Homo sapiens 142968 R-HSA-9697070 https://reactome.org/PathwayBrowser/#/R-HSA-9697070 lprG dissociates from LAM,LM TAS Homo sapiens 142968 R-HSA-9697077 https://reactome.org/PathwayBrowser/#/R-HSA-9697077 Rv1410c transports lprG:LM,LAM from cytosol to the cell wall TAS Homo sapiens 143082 R-MTU-9635440 https://reactome.org/PathwayBrowser/#/R-MTU-9635440 PapA5 transforms mycocerosyl to PDIM TAS Mycobacterium tuberculosis 143082 R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 143085 R-MTU-9635440 https://reactome.org/PathwayBrowser/#/R-MTU-9635440 PapA5 transforms mycocerosyl to PDIM TAS Mycobacterium tuberculosis 143085 R-MTU-9637589 https://reactome.org/PathwayBrowser/#/R-MTU-9637589 MmpL7 transports PDIM from the cytosol to the cell wall TAS Mycobacterium tuberculosis 143554 R-BTA-2395873 https://reactome.org/PathwayBrowser/#/R-BTA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Bos taurus 143554 R-CEL-2395873 https://reactome.org/PathwayBrowser/#/R-CEL-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Caenorhabditis elegans 143554 R-CFA-2395873 https://reactome.org/PathwayBrowser/#/R-CFA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Canis familiaris 143554 R-DME-2395873 https://reactome.org/PathwayBrowser/#/R-DME-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Drosophila melanogaster 143554 R-DRE-2395873 https://reactome.org/PathwayBrowser/#/R-DRE-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Danio rerio 143554 R-HSA-2395873 https://reactome.org/PathwayBrowser/#/R-HSA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP TAS Homo sapiens 143554 R-MMU-2395873 https://reactome.org/PathwayBrowser/#/R-MMU-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Mus musculus 143554 R-RNO-2395873 https://reactome.org/PathwayBrowser/#/R-RNO-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Rattus norvegicus 143554 R-SSC-2395873 https://reactome.org/PathwayBrowser/#/R-SSC-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Sus scrofa 143554 R-XTR-2395873 https://reactome.org/PathwayBrowser/#/R-XTR-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Xenopus tropicalis 143594 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 143594 R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 143594 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 143594 R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 143594 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 143594 R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 143594 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 143594 R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 143594 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 143594 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 143594 R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 143594 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 143594 R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 143594 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 143594 R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 143594 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 143594 R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 143594 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 143594 R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 143788 R-BTA-73813 https://reactome.org/PathwayBrowser/#/R-BTA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Bos taurus 143788 R-BTA-73814 https://reactome.org/PathwayBrowser/#/R-BTA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Bos taurus 143788 R-CEL-73813 https://reactome.org/PathwayBrowser/#/R-CEL-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Caenorhabditis elegans 143788 R-CEL-73814 https://reactome.org/PathwayBrowser/#/R-CEL-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Caenorhabditis elegans 143788 R-CFA-73813 https://reactome.org/PathwayBrowser/#/R-CFA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Canis familiaris 143788 R-CFA-73814 https://reactome.org/PathwayBrowser/#/R-CFA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Canis familiaris 143788 R-DDI-73813 https://reactome.org/PathwayBrowser/#/R-DDI-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Dictyostelium discoideum 143788 R-DDI-73814 https://reactome.org/PathwayBrowser/#/R-DDI-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Dictyostelium discoideum 143788 R-DME-73813 https://reactome.org/PathwayBrowser/#/R-DME-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Drosophila melanogaster 143788 R-DME-73814 https://reactome.org/PathwayBrowser/#/R-DME-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Drosophila melanogaster 143788 R-DRE-73813 https://reactome.org/PathwayBrowser/#/R-DRE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Danio rerio 143788 R-DRE-73814 https://reactome.org/PathwayBrowser/#/R-DRE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Danio rerio 143788 R-GGA-419145 https://reactome.org/PathwayBrowser/#/R-GGA-419145 5-phosphoribosylglycinamide (GAR) + 10-formyl-tetrahydrofolate => 5'-phosphoribosylformylglycinamide (FGAR) + tetrahydrofolate TAS Gallus gallus 143788 R-GGA-419153 https://reactome.org/PathwayBrowser/#/R-GGA-419153 5-phosphoribosylamine + glycine + ATP <=> 5-phosphoribosylglycinamide (GAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 143788 R-GGA-73813 https://reactome.org/PathwayBrowser/#/R-GGA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Gallus gallus 143788 R-GGA-73814 https://reactome.org/PathwayBrowser/#/R-GGA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Gallus gallus 143788 R-HSA-73813 https://reactome.org/PathwayBrowser/#/R-HSA-73813 GAR + 10-Formyl-THF => FGAR + THF TAS Homo sapiens 143788 R-HSA-73814 https://reactome.org/PathwayBrowser/#/R-HSA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi TAS Homo sapiens 143788 R-MMU-73813 https://reactome.org/PathwayBrowser/#/R-MMU-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Mus musculus 143788 R-MMU-73814 https://reactome.org/PathwayBrowser/#/R-MMU-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Mus musculus 143788 R-RNO-73813 https://reactome.org/PathwayBrowser/#/R-RNO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Rattus norvegicus 143788 R-RNO-73814 https://reactome.org/PathwayBrowser/#/R-RNO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Rattus norvegicus 143788 R-SCE-73813 https://reactome.org/PathwayBrowser/#/R-SCE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Saccharomyces cerevisiae 143788 R-SCE-73814 https://reactome.org/PathwayBrowser/#/R-SCE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Saccharomyces cerevisiae 143788 R-SPO-73813 https://reactome.org/PathwayBrowser/#/R-SPO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Schizosaccharomyces pombe 143788 R-SPO-73814 https://reactome.org/PathwayBrowser/#/R-SPO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Schizosaccharomyces pombe 143788 R-SSC-73813 https://reactome.org/PathwayBrowser/#/R-SSC-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Sus scrofa 143788 R-SSC-73814 https://reactome.org/PathwayBrowser/#/R-SSC-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Sus scrofa 143788 R-XTR-73813 https://reactome.org/PathwayBrowser/#/R-XTR-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Xenopus tropicalis 143788 R-XTR-73814 https://reactome.org/PathwayBrowser/#/R-XTR-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Xenopus tropicalis 143976 R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 143976 R-HSA-9681314 https://reactome.org/PathwayBrowser/#/R-HSA-9681314 Replication transcription complex binds SARS-CoV-1 genomic RNA TAS Homo sapiens 143976 R-HSA-9681651 https://reactome.org/PathwayBrowser/#/R-HSA-9681651 nsp8 generates RNA primers TAS Homo sapiens 143976 R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 143976 R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 143976 R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 143976 R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 143976 R-HSA-9682603 https://reactome.org/PathwayBrowser/#/R-HSA-9682603 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 143976 R-HSA-9682695 https://reactome.org/PathwayBrowser/#/R-HSA-9682695 nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template TAS Homo sapiens 143976 R-HSA-9683618 https://reactome.org/PathwayBrowser/#/R-HSA-9683618 mRNA3 is translated to protein 3a TAS Homo sapiens 143976 R-HSA-9683622 https://reactome.org/PathwayBrowser/#/R-HSA-9683622 mRNA5 is translated to protein M TAS Homo sapiens 143976 R-HSA-9683624 https://reactome.org/PathwayBrowser/#/R-HSA-9683624 mRNA2 is translated to Spike TAS Homo sapiens 143976 R-HSA-9683656 https://reactome.org/PathwayBrowser/#/R-HSA-9683656 mRNA4 is translated to protein E TAS Homo sapiens 143976 R-HSA-9683735 https://reactome.org/PathwayBrowser/#/R-HSA-9683735 mRNA9 is translated to Nucleoprotein TAS Homo sapiens 143976 R-HSA-9684030 https://reactome.org/PathwayBrowser/#/R-HSA-9684030 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 143976 R-HSA-9684032 https://reactome.org/PathwayBrowser/#/R-HSA-9684032 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 143976 R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 143976 R-HSA-9684229 https://reactome.org/PathwayBrowser/#/R-HSA-9684229 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 143976 R-HSA-9684234 https://reactome.org/PathwayBrowser/#/R-HSA-9684234 Encapsidation of SARS coronavirus genomic RNA TAS Homo sapiens 143976 R-HSA-9684238 https://reactome.org/PathwayBrowser/#/R-HSA-9684238 E and N are recruited to the M lattice TAS Homo sapiens 143976 R-HSA-9684241 https://reactome.org/PathwayBrowser/#/R-HSA-9684241 Recruitment of Spike trimer to assembling virion TAS Homo sapiens 143976 R-HSA-9684277 https://reactome.org/PathwayBrowser/#/R-HSA-9684277 mRNA1 is translated to pp1ab TAS Homo sapiens 143976 R-HSA-9684301 https://reactome.org/PathwayBrowser/#/R-HSA-9684301 mRNA1 is translated to pp1a TAS Homo sapiens 143976 R-HSA-9685519 https://reactome.org/PathwayBrowser/#/R-HSA-9685519 Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) TAS Homo sapiens 143976 R-HSA-9685531 https://reactome.org/PathwayBrowser/#/R-HSA-9685531 SARS virus buds into ERGIC lumen TAS Homo sapiens 143976 R-HSA-9685597 https://reactome.org/PathwayBrowser/#/R-HSA-9685597 RTC binds SARS-CoV-1 genomic RNA complement (minus strand) TAS Homo sapiens 143976 R-HSA-9685639 https://reactome.org/PathwayBrowser/#/R-HSA-9685639 Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching TAS Homo sapiens 143976 R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-HSA-9686174 https://reactome.org/PathwayBrowser/#/R-HSA-9686174 Accessory proteins are recruited to the maturing virion TAS Homo sapiens 143976 R-HSA-9687384 https://reactome.org/PathwayBrowser/#/R-HSA-9687384 SARS-CoV-1 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 143976 R-HSA-9687388 https://reactome.org/PathwayBrowser/#/R-HSA-9687388 SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 143976 R-HSA-9693589 https://reactome.org/PathwayBrowser/#/R-HSA-9693589 SARS-CoV-1 dsRNA intermediates bind DDX58 TAS Homo sapiens 143976 R-HSA-9693590 https://reactome.org/PathwayBrowser/#/R-HSA-9693590 SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC IEA Homo sapiens 143976 R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 143976 R-HSA-9694274 https://reactome.org/PathwayBrowser/#/R-HSA-9694274 mRNA1 is translated to pp1ab IEA Homo sapiens 143976 R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 143976 R-HSA-9694280 https://reactome.org/PathwayBrowser/#/R-HSA-9694280 mRNA4 is translated to protein E TAS Homo sapiens 143976 R-HSA-9694281 https://reactome.org/PathwayBrowser/#/R-HSA-9694281 Encapsidation of SARS coronavirus genomic RNA IEA Homo sapiens 143976 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 143976 R-HSA-9694334 https://reactome.org/PathwayBrowser/#/R-HSA-9694334 mRNA1 is translated to pp1a IEA Homo sapiens 143976 R-HSA-9694344 https://reactome.org/PathwayBrowser/#/R-HSA-9694344 Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching IEA Homo sapiens 143976 R-HSA-9694370 https://reactome.org/PathwayBrowser/#/R-HSA-9694370 mRNA9a is translated to Nucleoprotein TAS Homo sapiens 143976 R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 143976 R-HSA-9694444 https://reactome.org/PathwayBrowser/#/R-HSA-9694444 E and N are recruited to the M lattice IEA Homo sapiens 143976 R-HSA-9694447 https://reactome.org/PathwayBrowser/#/R-HSA-9694447 mRNA2 is translated to Spike TAS Homo sapiens 143976 R-HSA-9694454 https://reactome.org/PathwayBrowser/#/R-HSA-9694454 Replication transcription complex binds SARS-CoV-2 genomic RNA TAS Homo sapiens 143976 R-HSA-9694455 https://reactome.org/PathwayBrowser/#/R-HSA-9694455 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 143976 R-HSA-9694471 https://reactome.org/PathwayBrowser/#/R-HSA-9694471 Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) TAS Homo sapiens 143976 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-HSA-9694495 https://reactome.org/PathwayBrowser/#/R-HSA-9694495 RTC binds SARS-CoV-2 genomic RNA complement (minus strand) IEA Homo sapiens 143976 R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 143976 R-HSA-9694528 https://reactome.org/PathwayBrowser/#/R-HSA-9694528 Accessory proteins are recruited to the maturing virion IEA Homo sapiens 143976 R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 143976 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 143976 R-HSA-9694553 https://reactome.org/PathwayBrowser/#/R-HSA-9694553 Recruitment of Spike trimer to assembling virion IEA Homo sapiens 143976 R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 143976 R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 143976 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 143976 R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 143976 R-HSA-9694633 https://reactome.org/PathwayBrowser/#/R-HSA-9694633 SARS virus buds into ERGIC lumen IEA Homo sapiens 143976 R-HSA-9694641 https://reactome.org/PathwayBrowser/#/R-HSA-9694641 Viral release IEA Homo sapiens 143976 R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 143976 R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 143976 R-HSA-9694677 https://reactome.org/PathwayBrowser/#/R-HSA-9694677 ZCRB1 binds 5'UTR of SARS-CoV-2 genomic RNA IEA Homo sapiens 143976 R-HSA-9694681 https://reactome.org/PathwayBrowser/#/R-HSA-9694681 mRNA5 is translated to protein M TAS Homo sapiens 143976 R-HSA-9694689 https://reactome.org/PathwayBrowser/#/R-HSA-9694689 Fusion and Release of SARS-CoV-2 Nucleocapsid IEA Homo sapiens 143976 R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 143976 R-HSA-9694723 https://reactome.org/PathwayBrowser/#/R-HSA-9694723 Uncoating of SARS-CoV-2 Genome IEA Homo sapiens 143976 R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 143976 R-HSA-9694794 https://reactome.org/PathwayBrowser/#/R-HSA-9694794 mRNA3 is translated to protein 3a TAS Homo sapiens 143976 R-HSA-9697423 https://reactome.org/PathwayBrowser/#/R-HSA-9697423 Endocytosis of SARS-CoV-2 Virion IEA Homo sapiens 143976 R-HSA-9698988 https://reactome.org/PathwayBrowser/#/R-HSA-9698988 Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid TAS Homo sapiens 143976 R-HSA-9699007 https://reactome.org/PathwayBrowser/#/R-HSA-9699007 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 143976 R-HSA-9705961 https://reactome.org/PathwayBrowser/#/R-HSA-9705961 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 143976 R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 143976 R-HSA-9727292 https://reactome.org/PathwayBrowser/#/R-HSA-9727292 mRNA6 is translated to protein 6 TAS Homo sapiens 143976 R-HSA-9727297 https://reactome.org/PathwayBrowser/#/R-HSA-9727297 mRNA7 is translated to protein 7a TAS Homo sapiens 143976 R-HSA-9727303 https://reactome.org/PathwayBrowser/#/R-HSA-9727303 mRNA9 is translated to protein 9b TAS Homo sapiens 143976 R-HSA-9727305 https://reactome.org/PathwayBrowser/#/R-HSA-9727305 mRNA8 is translated to protein 8 TAS Homo sapiens 143976 R-HSA-9754745 https://reactome.org/PathwayBrowser/#/R-HSA-9754745 IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 143976 R-HSA-9755252 https://reactome.org/PathwayBrowser/#/R-HSA-9755252 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 143976 R-HSA-9755258 https://reactome.org/PathwayBrowser/#/R-HSA-9755258 DDX58 binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 143976 R-HSA-9755368 https://reactome.org/PathwayBrowser/#/R-HSA-9755368 TLR2:TLR1 binds SARS-CoV-2 E pentamer TAS Homo sapiens 143976 R-HSA-9756574 https://reactome.org/PathwayBrowser/#/R-HSA-9756574 SARS-CoV-2 S binds SFTPD 12mer TAS Homo sapiens 143976 R-HSA-9759709 https://reactome.org/PathwayBrowser/#/R-HSA-9759709 CNBP binds SARS-CoV-2 G-rich RNA TAS Homo sapiens 143976 R-HSA-9760510 https://reactome.org/PathwayBrowser/#/R-HSA-9760510 LARP1 binds SARS-CoV-2 RNA TAS Homo sapiens 143976 R-HSA-9769949 https://reactome.org/PathwayBrowser/#/R-HSA-9769949 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage TAS Homo sapiens 143976 R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 144353 R-BTA-9693324 https://reactome.org/PathwayBrowser/#/R-BTA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Bos taurus 144353 R-CFA-9693324 https://reactome.org/PathwayBrowser/#/R-CFA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Canis familiaris 144353 R-GGA-9693324 https://reactome.org/PathwayBrowser/#/R-GGA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Gallus gallus 144353 R-HSA-9693324 https://reactome.org/PathwayBrowser/#/R-HSA-9693324 Disulfiram covalently modifies Cys191 in GSDMD TAS Homo sapiens 144353 R-MMU-9693324 https://reactome.org/PathwayBrowser/#/R-MMU-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Mus musculus 144353 R-RNO-9693324 https://reactome.org/PathwayBrowser/#/R-RNO-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Rattus norvegicus 144353 R-SSC-9693324 https://reactome.org/PathwayBrowser/#/R-SSC-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Sus scrofa 144842 R-BTA-2161187 https://reactome.org/PathwayBrowser/#/R-BTA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Bos taurus 144842 R-BTA-9731632 https://reactome.org/PathwayBrowser/#/R-BTA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Bos taurus 144842 R-CEL-2161187 https://reactome.org/PathwayBrowser/#/R-CEL-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Caenorhabditis elegans 144842 R-CFA-2161187 https://reactome.org/PathwayBrowser/#/R-CFA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Canis familiaris 144842 R-CFA-9731632 https://reactome.org/PathwayBrowser/#/R-CFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Canis familiaris 144842 R-DME-2161187 https://reactome.org/PathwayBrowser/#/R-DME-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Drosophila melanogaster 144842 R-DRE-2161187 https://reactome.org/PathwayBrowser/#/R-DRE-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Danio rerio 144842 R-DRE-9731632 https://reactome.org/PathwayBrowser/#/R-DRE-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Danio rerio 144842 R-GGA-2161187 https://reactome.org/PathwayBrowser/#/R-GGA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Gallus gallus 144842 R-GGA-9731632 https://reactome.org/PathwayBrowser/#/R-GGA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Gallus gallus 144842 R-HSA-2161187 https://reactome.org/PathwayBrowser/#/R-HSA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine TAS Homo sapiens 144842 R-HSA-9731632 https://reactome.org/PathwayBrowser/#/R-HSA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP TAS Homo sapiens 144842 R-MMU-2161187 https://reactome.org/PathwayBrowser/#/R-MMU-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Mus musculus 144842 R-MMU-9731632 https://reactome.org/PathwayBrowser/#/R-MMU-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Mus musculus 144842 R-PFA-9731632 https://reactome.org/PathwayBrowser/#/R-PFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Plasmodium falciparum 144842 R-RNO-9731632 https://reactome.org/PathwayBrowser/#/R-RNO-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Rattus norvegicus 144842 R-SSC-2161187 https://reactome.org/PathwayBrowser/#/R-SSC-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Sus scrofa 144842 R-SSC-9731632 https://reactome.org/PathwayBrowser/#/R-SSC-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Sus scrofa 144842 R-XTR-2161187 https://reactome.org/PathwayBrowser/#/R-XTR-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Xenopus tropicalis 144842 R-XTR-9731632 https://reactome.org/PathwayBrowser/#/R-XTR-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Xenopus tropicalis 145373 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 145373 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 145373 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 145373 R-HSA-9695831 https://reactome.org/PathwayBrowser/#/R-HSA-9695831 FLT3 binds type II TKI TAS Homo sapiens 145373 R-HSA-9702510 https://reactome.org/PathwayBrowser/#/R-HSA-9702510 FLT mutants bind type II TKIs TAS Homo sapiens 145373 R-HSA-9702607 https://reactome.org/PathwayBrowser/#/R-HSA-9702607 pexidartinib-resistant FLT3 mutants don't bind pexidartinib TAS Homo sapiens 145373 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 145373 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 145694 R-BTA-2395873 https://reactome.org/PathwayBrowser/#/R-BTA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Bos taurus 145694 R-CEL-2395873 https://reactome.org/PathwayBrowser/#/R-CEL-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Caenorhabditis elegans 145694 R-CFA-2395873 https://reactome.org/PathwayBrowser/#/R-CFA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Canis familiaris 145694 R-DME-2395873 https://reactome.org/PathwayBrowser/#/R-DME-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Drosophila melanogaster 145694 R-DRE-2395873 https://reactome.org/PathwayBrowser/#/R-DRE-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Danio rerio 145694 R-HSA-2395873 https://reactome.org/PathwayBrowser/#/R-HSA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP TAS Homo sapiens 145694 R-MMU-2395873 https://reactome.org/PathwayBrowser/#/R-MMU-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Mus musculus 145694 R-RNO-2395873 https://reactome.org/PathwayBrowser/#/R-RNO-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Rattus norvegicus 145694 R-SSC-2395873 https://reactome.org/PathwayBrowser/#/R-SSC-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Sus scrofa 145694 R-XTR-2395873 https://reactome.org/PathwayBrowser/#/R-XTR-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Xenopus tropicalis 14597 R-BTA-5696213 https://reactome.org/PathwayBrowser/#/R-BTA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Bos taurus 14597 R-BTA-5696230 https://reactome.org/PathwayBrowser/#/R-BTA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Bos taurus 14597 R-CEL-5696230 https://reactome.org/PathwayBrowser/#/R-CEL-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Caenorhabditis elegans 14597 R-CFA-5696230 https://reactome.org/PathwayBrowser/#/R-CFA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Canis familiaris 14597 R-DME-5696230 https://reactome.org/PathwayBrowser/#/R-DME-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Drosophila melanogaster 14597 R-DRE-5696213 https://reactome.org/PathwayBrowser/#/R-DRE-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Danio rerio 14597 R-DRE-5696230 https://reactome.org/PathwayBrowser/#/R-DRE-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Danio rerio 14597 R-GGA-5696213 https://reactome.org/PathwayBrowser/#/R-GGA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Gallus gallus 14597 R-GGA-5696230 https://reactome.org/PathwayBrowser/#/R-GGA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Gallus gallus 14597 R-HSA-5696213 https://reactome.org/PathwayBrowser/#/R-HSA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite TAS Homo sapiens 14597 R-HSA-5696230 https://reactome.org/PathwayBrowser/#/R-HSA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite TAS Homo sapiens 14597 R-MMU-5696213 https://reactome.org/PathwayBrowser/#/R-MMU-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Mus musculus 14597 R-MMU-5696230 https://reactome.org/PathwayBrowser/#/R-MMU-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Mus musculus 14597 R-RNO-5696213 https://reactome.org/PathwayBrowser/#/R-RNO-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Rattus norvegicus 14597 R-RNO-5696230 https://reactome.org/PathwayBrowser/#/R-RNO-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Rattus norvegicus 14597 R-SSC-5696213 https://reactome.org/PathwayBrowser/#/R-SSC-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Sus scrofa 14597 R-SSC-5696230 https://reactome.org/PathwayBrowser/#/R-SSC-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Sus scrofa 14597 R-XTR-5696213 https://reactome.org/PathwayBrowser/#/R-XTR-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Xenopus tropicalis 14597 R-XTR-5696230 https://reactome.org/PathwayBrowser/#/R-XTR-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Xenopus tropicalis 14649 R-BTA-8869627 https://reactome.org/PathwayBrowser/#/R-BTA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Bos taurus 14649 R-BTA-8869633 https://reactome.org/PathwayBrowser/#/R-BTA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Bos taurus 14649 R-BTA-8939959 https://reactome.org/PathwayBrowser/#/R-BTA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Bos taurus 14649 R-BTA-8940070 https://reactome.org/PathwayBrowser/#/R-BTA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Bos taurus 14649 R-BTA-8940074 https://reactome.org/PathwayBrowser/#/R-BTA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Bos taurus 14649 R-CEL-8939959 https://reactome.org/PathwayBrowser/#/R-CEL-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Caenorhabditis elegans 14649 R-CFA-8869633 https://reactome.org/PathwayBrowser/#/R-CFA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Canis familiaris 14649 R-CFA-8939959 https://reactome.org/PathwayBrowser/#/R-CFA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Canis familiaris 14649 R-CFA-8940070 https://reactome.org/PathwayBrowser/#/R-CFA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Canis familiaris 14649 R-CFA-8940074 https://reactome.org/PathwayBrowser/#/R-CFA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Canis familiaris 14649 R-DDI-8869627 https://reactome.org/PathwayBrowser/#/R-DDI-8869627 NMRK2 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 14649 R-DDI-8869633 https://reactome.org/PathwayBrowser/#/R-DDI-8869633 NMRK1 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 14649 R-DDI-8939959 https://reactome.org/PathwayBrowser/#/R-DDI-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Dictyostelium discoideum 14649 R-DME-8869627 https://reactome.org/PathwayBrowser/#/R-DME-8869627 NMRK2 phosphorylates NR to yield NMN IEA Drosophila melanogaster 14649 R-DME-8869633 https://reactome.org/PathwayBrowser/#/R-DME-8869633 NMRK1 phosphorylates NR to yield NMN IEA Drosophila melanogaster 14649 R-DME-8939959 https://reactome.org/PathwayBrowser/#/R-DME-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Drosophila melanogaster 14649 R-DME-8940070 https://reactome.org/PathwayBrowser/#/R-DME-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Drosophila melanogaster 14649 R-DME-8940074 https://reactome.org/PathwayBrowser/#/R-DME-8940074 NT5E:Zn2+ hydrolyses NMN IEA Drosophila melanogaster 14649 R-DRE-8869627 https://reactome.org/PathwayBrowser/#/R-DRE-8869627 NMRK2 phosphorylates NR to yield NMN IEA Danio rerio 14649 R-DRE-8939959 https://reactome.org/PathwayBrowser/#/R-DRE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Danio rerio 14649 R-DRE-8940070 https://reactome.org/PathwayBrowser/#/R-DRE-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Danio rerio 14649 R-DRE-8940074 https://reactome.org/PathwayBrowser/#/R-DRE-8940074 NT5E:Zn2+ hydrolyses NMN IEA Danio rerio 14649 R-GGA-8869627 https://reactome.org/PathwayBrowser/#/R-GGA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Gallus gallus 14649 R-GGA-8869633 https://reactome.org/PathwayBrowser/#/R-GGA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Gallus gallus 14649 R-GGA-8939959 https://reactome.org/PathwayBrowser/#/R-GGA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Gallus gallus 14649 R-GGA-8940070 https://reactome.org/PathwayBrowser/#/R-GGA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Gallus gallus 14649 R-GGA-8940074 https://reactome.org/PathwayBrowser/#/R-GGA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Gallus gallus 14649 R-HSA-8869627 https://reactome.org/PathwayBrowser/#/R-HSA-8869627 NMRK2 phosphorylates NR to yield NMN TAS Homo sapiens 14649 R-HSA-8869633 https://reactome.org/PathwayBrowser/#/R-HSA-8869633 NMRK1 phosphorylates NR to yield NMN TAS Homo sapiens 14649 R-HSA-8939959 https://reactome.org/PathwayBrowser/#/R-HSA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ TAS Homo sapiens 14649 R-HSA-8940070 https://reactome.org/PathwayBrowser/#/R-HSA-8940070 NT5E:Zn2+ hydrolyses NAD+ TAS Homo sapiens 14649 R-HSA-8940074 https://reactome.org/PathwayBrowser/#/R-HSA-8940074 NT5E:Zn2+ hydrolyses NMN TAS Homo sapiens 14649 R-MMU-8869627 https://reactome.org/PathwayBrowser/#/R-MMU-8869627 NMRK2 phosphorylates NR to yield NMN IEA Mus musculus 14649 R-MMU-8869633 https://reactome.org/PathwayBrowser/#/R-MMU-8869633 NMRK1 phosphorylates NR to yield NMN IEA Mus musculus 14649 R-MMU-8939959 https://reactome.org/PathwayBrowser/#/R-MMU-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Mus musculus 14649 R-MMU-8940070 https://reactome.org/PathwayBrowser/#/R-MMU-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Mus musculus 14649 R-MMU-8940074 https://reactome.org/PathwayBrowser/#/R-MMU-8940074 NT5E:Zn2+ hydrolyses NMN IEA Mus musculus 14649 R-RNO-8869633 https://reactome.org/PathwayBrowser/#/R-RNO-8869633 NMRK1 phosphorylates NR to yield NMN IEA Rattus norvegicus 14649 R-RNO-8939959 https://reactome.org/PathwayBrowser/#/R-RNO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Rattus norvegicus 14649 R-RNO-8940070 https://reactome.org/PathwayBrowser/#/R-RNO-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Rattus norvegicus 14649 R-RNO-8940074 https://reactome.org/PathwayBrowser/#/R-RNO-8940074 NT5E:Zn2+ hydrolyses NMN IEA Rattus norvegicus 14649 R-SCE-8939959 https://reactome.org/PathwayBrowser/#/R-SCE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Saccharomyces cerevisiae 14649 R-SPO-8939959 https://reactome.org/PathwayBrowser/#/R-SPO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Schizosaccharomyces pombe 14649 R-SSC-8869627 https://reactome.org/PathwayBrowser/#/R-SSC-8869627 NMRK2 phosphorylates NR to yield NMN IEA Sus scrofa 14649 R-SSC-8869633 https://reactome.org/PathwayBrowser/#/R-SSC-8869633 NMRK1 phosphorylates NR to yield NMN IEA Sus scrofa 14649 R-SSC-8939959 https://reactome.org/PathwayBrowser/#/R-SSC-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Sus scrofa 14649 R-SSC-8940070 https://reactome.org/PathwayBrowser/#/R-SSC-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Sus scrofa 14649 R-SSC-8940074 https://reactome.org/PathwayBrowser/#/R-SSC-8940074 NT5E:Zn2+ hydrolyses NMN IEA Sus scrofa 14649 R-XTR-8940070 https://reactome.org/PathwayBrowser/#/R-XTR-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Xenopus tropicalis 14649 R-XTR-8940074 https://reactome.org/PathwayBrowser/#/R-XTR-8940074 NT5E:Zn2+ hydrolyses NMN IEA Xenopus tropicalis 147286 R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 147286 R-BTA-73813 https://reactome.org/PathwayBrowser/#/R-BTA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Bos taurus 147286 R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 147286 R-CEL-73813 https://reactome.org/PathwayBrowser/#/R-CEL-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Caenorhabditis elegans 147286 R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 147286 R-CFA-73813 https://reactome.org/PathwayBrowser/#/R-CFA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Canis familiaris 147286 R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 147286 R-DDI-73813 https://reactome.org/PathwayBrowser/#/R-DDI-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Dictyostelium discoideum 147286 R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 147286 R-DME-73813 https://reactome.org/PathwayBrowser/#/R-DME-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Drosophila melanogaster 147286 R-DRE-73813 https://reactome.org/PathwayBrowser/#/R-DRE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Danio rerio 147286 R-GGA-419144 https://reactome.org/PathwayBrowser/#/R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate TAS Gallus gallus 147286 R-GGA-419145 https://reactome.org/PathwayBrowser/#/R-GGA-419145 5-phosphoribosylglycinamide (GAR) + 10-formyl-tetrahydrofolate => 5'-phosphoribosylformylglycinamide (FGAR) + tetrahydrofolate TAS Gallus gallus 147286 R-GGA-73813 https://reactome.org/PathwayBrowser/#/R-GGA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Gallus gallus 147286 R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 147286 R-HSA-73813 https://reactome.org/PathwayBrowser/#/R-HSA-73813 GAR + 10-Formyl-THF => FGAR + THF TAS Homo sapiens 147286 R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 147286 R-MMU-73813 https://reactome.org/PathwayBrowser/#/R-MMU-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Mus musculus 147286 R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 147286 R-RNO-73813 https://reactome.org/PathwayBrowser/#/R-RNO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Rattus norvegicus 147286 R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 147286 R-SCE-73813 https://reactome.org/PathwayBrowser/#/R-SCE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Saccharomyces cerevisiae 147286 R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 147286 R-SPO-73813 https://reactome.org/PathwayBrowser/#/R-SPO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Schizosaccharomyces pombe 147286 R-SSC-73813 https://reactome.org/PathwayBrowser/#/R-SSC-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Sus scrofa 147286 R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 147286 R-XTR-73813 https://reactome.org/PathwayBrowser/#/R-XTR-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Xenopus tropicalis 147287 R-BTA-73810 https://reactome.org/PathwayBrowser/#/R-BTA-73810 FGAM + ATP => AIR + ADP + Pi IEA Bos taurus 147287 R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 147287 R-CEL-73810 https://reactome.org/PathwayBrowser/#/R-CEL-73810 FGAM + ATP => AIR + ADP + Pi IEA Caenorhabditis elegans 147287 R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 147287 R-CFA-73810 https://reactome.org/PathwayBrowser/#/R-CFA-73810 FGAM + ATP => AIR + ADP + Pi IEA Canis familiaris 147287 R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 147287 R-DDI-73810 https://reactome.org/PathwayBrowser/#/R-DDI-73810 FGAM + ATP => AIR + ADP + Pi IEA Dictyostelium discoideum 147287 R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 147287 R-DME-73810 https://reactome.org/PathwayBrowser/#/R-DME-73810 FGAM + ATP => AIR + ADP + Pi IEA Drosophila melanogaster 147287 R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 147287 R-DRE-73810 https://reactome.org/PathwayBrowser/#/R-DRE-73810 FGAM + ATP => AIR + ADP + Pi IEA Danio rerio 147287 R-GGA-419144 https://reactome.org/PathwayBrowser/#/R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate TAS Gallus gallus 147287 R-GGA-419157 https://reactome.org/PathwayBrowser/#/R-GGA-419157 5'-phosphoribosylformylglycinamidine (FGAM) + ATP => 5'-phosphoribosyl-5-aminoimidazole (AIR) + ADP + orthophosphate TAS Gallus gallus 147287 R-GGA-73810 https://reactome.org/PathwayBrowser/#/R-GGA-73810 FGAM + ATP => AIR + ADP + Pi IEA Gallus gallus 147287 R-HSA-73810 https://reactome.org/PathwayBrowser/#/R-HSA-73810 FGAM + ATP => AIR + ADP + Pi TAS Homo sapiens 147287 R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 147287 R-MMU-73810 https://reactome.org/PathwayBrowser/#/R-MMU-73810 FGAM + ATP => AIR + ADP + Pi IEA Mus musculus 147287 R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 147287 R-RNO-73810 https://reactome.org/PathwayBrowser/#/R-RNO-73810 FGAM + ATP => AIR + ADP + Pi IEA Rattus norvegicus 147287 R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 147287 R-SCE-73810 https://reactome.org/PathwayBrowser/#/R-SCE-73810 FGAM + ATP => AIR + ADP + Pi IEA Saccharomyces cerevisiae 147287 R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 147287 R-SPO-73810 https://reactome.org/PathwayBrowser/#/R-SPO-73810 FGAM + ATP => AIR + ADP + Pi IEA Schizosaccharomyces pombe 147287 R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 147287 R-SSC-73810 https://reactome.org/PathwayBrowser/#/R-SSC-73810 FGAM + ATP => AIR + ADP + Pi IEA Sus scrofa 147287 R-XTR-73810 https://reactome.org/PathwayBrowser/#/R-XTR-73810 FGAM + ATP => AIR + ADP + Pi IEA Xenopus tropicalis 147287 R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 147411 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 147411 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 147411 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 149484 R-HSA-9683467 https://reactome.org/PathwayBrowser/#/R-HSA-9683467 CQ, HCQ are protonated to CQ2+, HCQ2+ TAS Homo sapiens 14949 R-BTA-5693967 https://reactome.org/PathwayBrowser/#/R-BTA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Bos taurus 14949 R-BTA-5693977 https://reactome.org/PathwayBrowser/#/R-BTA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Bos taurus 14949 R-CEL-5693967 https://reactome.org/PathwayBrowser/#/R-CEL-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Caenorhabditis elegans 14949 R-CEL-5693977 https://reactome.org/PathwayBrowser/#/R-CEL-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Caenorhabditis elegans 14949 R-CFA-5693967 https://reactome.org/PathwayBrowser/#/R-CFA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Canis familiaris 14949 R-CFA-5693977 https://reactome.org/PathwayBrowser/#/R-CFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Canis familiaris 14949 R-DDI-5693967 https://reactome.org/PathwayBrowser/#/R-DDI-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Dictyostelium discoideum 14949 R-DDI-5693977 https://reactome.org/PathwayBrowser/#/R-DDI-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Dictyostelium discoideum 14949 R-DME-5693967 https://reactome.org/PathwayBrowser/#/R-DME-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Drosophila melanogaster 14949 R-DME-5693977 https://reactome.org/PathwayBrowser/#/R-DME-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Drosophila melanogaster 14949 R-DRE-5693967 https://reactome.org/PathwayBrowser/#/R-DRE-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Danio rerio 14949 R-DRE-5693977 https://reactome.org/PathwayBrowser/#/R-DRE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Danio rerio 14949 R-GGA-5693967 https://reactome.org/PathwayBrowser/#/R-GGA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Gallus gallus 14949 R-HSA-5693967 https://reactome.org/PathwayBrowser/#/R-HSA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly TAS Homo sapiens 14949 R-HSA-5693977 https://reactome.org/PathwayBrowser/#/R-HSA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF TAS Homo sapiens 14949 R-MMU-5693967 https://reactome.org/PathwayBrowser/#/R-MMU-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Mus musculus 14949 R-MMU-5693977 https://reactome.org/PathwayBrowser/#/R-MMU-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Mus musculus 14949 R-PFA-5693977 https://reactome.org/PathwayBrowser/#/R-PFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Plasmodium falciparum 14949 R-RNO-5693967 https://reactome.org/PathwayBrowser/#/R-RNO-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Rattus norvegicus 14949 R-RNO-5693977 https://reactome.org/PathwayBrowser/#/R-RNO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Rattus norvegicus 14949 R-SCE-5693967 https://reactome.org/PathwayBrowser/#/R-SCE-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Saccharomyces cerevisiae 14949 R-SCE-5693977 https://reactome.org/PathwayBrowser/#/R-SCE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Saccharomyces cerevisiae 14949 R-SPO-5693967 https://reactome.org/PathwayBrowser/#/R-SPO-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Schizosaccharomyces pombe 14949 R-SPO-5693977 https://reactome.org/PathwayBrowser/#/R-SPO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Schizosaccharomyces pombe 14949 R-SSC-5693967 https://reactome.org/PathwayBrowser/#/R-SSC-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Sus scrofa 14949 R-SSC-5693977 https://reactome.org/PathwayBrowser/#/R-SSC-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Sus scrofa 14949 R-XTR-5693977 https://reactome.org/PathwayBrowser/#/R-XTR-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Xenopus tropicalis 149564 R-HSA-9683467 https://reactome.org/PathwayBrowser/#/R-HSA-9683467 CQ, HCQ are protonated to CQ2+, HCQ2+ TAS Homo sapiens 15138 R-MTU-936590 https://reactome.org/PathwayBrowser/#/R-MTU-936590 sulfur transfer to carrier protein TAS Mycobacterium tuberculosis 15138 R-MTU-936642 https://reactome.org/PathwayBrowser/#/R-MTU-936642 deacetylation of O-acetylserine and sulfhydrylation using CysK1 TAS Mycobacterium tuberculosis 15138 R-MTU-936703 https://reactome.org/PathwayBrowser/#/R-MTU-936703 sulfite is reduced to sulfide TAS Mycobacterium tuberculosis 15138 R-MTU-936745 https://reactome.org/PathwayBrowser/#/R-MTU-936745 deacetylation of O-acetylserine and sulfhydrylation using CysK2 TAS Mycobacterium tuberculosis 15266 R-BTA-1474184 https://reactome.org/PathwayBrowser/#/R-BTA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Bos taurus 15266 R-BTA-3159253 https://reactome.org/PathwayBrowser/#/R-BTA-3159253 MMAB adenosylates cob(I)alamin IEA Bos taurus 15266 R-CEL-1474184 https://reactome.org/PathwayBrowser/#/R-CEL-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Caenorhabditis elegans 15266 R-CEL-3159253 https://reactome.org/PathwayBrowser/#/R-CEL-3159253 MMAB adenosylates cob(I)alamin IEA Caenorhabditis elegans 15266 R-CFA-3159253 https://reactome.org/PathwayBrowser/#/R-CFA-3159253 MMAB adenosylates cob(I)alamin IEA Canis familiaris 15266 R-DDI-1474184 https://reactome.org/PathwayBrowser/#/R-DDI-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Dictyostelium discoideum 15266 R-DDI-3159253 https://reactome.org/PathwayBrowser/#/R-DDI-3159253 MMAB adenosylates cob(I)alamin IEA Dictyostelium discoideum 15266 R-DME-1474184 https://reactome.org/PathwayBrowser/#/R-DME-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Drosophila melanogaster 15266 R-DRE-1474184 https://reactome.org/PathwayBrowser/#/R-DRE-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Danio rerio 15266 R-GGA-1474184 https://reactome.org/PathwayBrowser/#/R-GGA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Gallus gallus 15266 R-GGA-3159253 https://reactome.org/PathwayBrowser/#/R-GGA-3159253 MMAB adenosylates cob(I)alamin IEA Gallus gallus 15266 R-HSA-1474184 https://reactome.org/PathwayBrowser/#/R-HSA-1474184 DHNTP is dephosphorylated by PTPS to PTHP TAS Homo sapiens 15266 R-HSA-3159253 https://reactome.org/PathwayBrowser/#/R-HSA-3159253 MMAB adenosylates cob(I)alamin TAS Homo sapiens 15266 R-MMU-1474184 https://reactome.org/PathwayBrowser/#/R-MMU-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Mus musculus 15266 R-MMU-3159253 https://reactome.org/PathwayBrowser/#/R-MMU-3159253 MMAB adenosylates cob(I)alamin IEA Mus musculus 15266 R-PFA-1474184 https://reactome.org/PathwayBrowser/#/R-PFA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Plasmodium falciparum 15266 R-RNO-1474184 https://reactome.org/PathwayBrowser/#/R-RNO-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Rattus norvegicus 15266 R-RNO-3159253 https://reactome.org/PathwayBrowser/#/R-RNO-3159253 MMAB adenosylates cob(I)alamin IEA Rattus norvegicus 15266 R-SSC-1474184 https://reactome.org/PathwayBrowser/#/R-SSC-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Sus scrofa 15266 R-SSC-3159253 https://reactome.org/PathwayBrowser/#/R-SSC-3159253 MMAB adenosylates cob(I)alamin IEA Sus scrofa 15266 R-XTR-1474184 https://reactome.org/PathwayBrowser/#/R-XTR-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Xenopus tropicalis 15266 R-XTR-3159253 https://reactome.org/PathwayBrowser/#/R-XTR-3159253 MMAB adenosylates cob(I)alamin IEA Xenopus tropicalis 15343 R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 15343 R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 15343 R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 15343 R-BTA-5696091 https://reactome.org/PathwayBrowser/#/R-BTA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Bos taurus 15343 R-BTA-5696415 https://reactome.org/PathwayBrowser/#/R-BTA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Bos taurus 15343 R-BTA-6787321 https://reactome.org/PathwayBrowser/#/R-BTA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Bos taurus 15343 R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 15343 R-BTA-71707 https://reactome.org/PathwayBrowser/#/R-BTA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Bos taurus 15343 R-BTA-71723 https://reactome.org/PathwayBrowser/#/R-BTA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Bos taurus 15343 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 15343 R-CEL-5696091 https://reactome.org/PathwayBrowser/#/R-CEL-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Caenorhabditis elegans 15343 R-CEL-5696415 https://reactome.org/PathwayBrowser/#/R-CEL-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Caenorhabditis elegans 15343 R-CEL-6787321 https://reactome.org/PathwayBrowser/#/R-CEL-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Caenorhabditis elegans 15343 R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 15343 R-CEL-71707 https://reactome.org/PathwayBrowser/#/R-CEL-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Caenorhabditis elegans 15343 R-CEL-71723 https://reactome.org/PathwayBrowser/#/R-CEL-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Caenorhabditis elegans 15343 R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 15343 R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 15343 R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 15343 R-CFA-5696091 https://reactome.org/PathwayBrowser/#/R-CFA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Canis familiaris 15343 R-CFA-5696415 https://reactome.org/PathwayBrowser/#/R-CFA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Canis familiaris 15343 R-CFA-6787321 https://reactome.org/PathwayBrowser/#/R-CFA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Canis familiaris 15343 R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 15343 R-CFA-71707 https://reactome.org/PathwayBrowser/#/R-CFA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Canis familiaris 15343 R-CFA-71723 https://reactome.org/PathwayBrowser/#/R-CFA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Canis familiaris 15343 R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 15343 R-DDI-5696091 https://reactome.org/PathwayBrowser/#/R-DDI-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Dictyostelium discoideum 15343 R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 15343 R-DDI-71707 https://reactome.org/PathwayBrowser/#/R-DDI-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Dictyostelium discoideum 15343 R-DDI-71723 https://reactome.org/PathwayBrowser/#/R-DDI-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Dictyostelium discoideum 15343 R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 15343 R-DME-5696091 https://reactome.org/PathwayBrowser/#/R-DME-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Drosophila melanogaster 15343 R-DME-5696415 https://reactome.org/PathwayBrowser/#/R-DME-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Drosophila melanogaster 15343 R-DME-6787321 https://reactome.org/PathwayBrowser/#/R-DME-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Drosophila melanogaster 15343 R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 15343 R-DME-71707 https://reactome.org/PathwayBrowser/#/R-DME-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Drosophila melanogaster 15343 R-DME-71723 https://reactome.org/PathwayBrowser/#/R-DME-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Drosophila melanogaster 15343 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 15343 R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 15343 R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 15343 R-DRE-5696091 https://reactome.org/PathwayBrowser/#/R-DRE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Danio rerio 15343 R-DRE-5696415 https://reactome.org/PathwayBrowser/#/R-DRE-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Danio rerio 15343 R-DRE-6787321 https://reactome.org/PathwayBrowser/#/R-DRE-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Danio rerio 15343 R-DRE-71707 https://reactome.org/PathwayBrowser/#/R-DRE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Danio rerio 15343 R-DRE-71723 https://reactome.org/PathwayBrowser/#/R-DRE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Danio rerio 15343 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 15343 R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 15343 R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 15343 R-GGA-353356 https://reactome.org/PathwayBrowser/#/R-GGA-353356 Reversal of Alkylation Damage By DNA Dioxygenases TAS Gallus gallus 15343 R-GGA-5696415 https://reactome.org/PathwayBrowser/#/R-GGA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Gallus gallus 15343 R-GGA-6787321 https://reactome.org/PathwayBrowser/#/R-GGA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Gallus gallus 15343 R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 15343 R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus 15343 R-GGA-71723 https://reactome.org/PathwayBrowser/#/R-GGA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Gallus gallus 15343 R-HSA-112121 https://reactome.org/PathwayBrowser/#/R-HSA-112121 Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 TAS Homo sapiens 15343 R-HSA-112125 https://reactome.org/PathwayBrowser/#/R-HSA-112125 Oxidative dealkylation of 1-EtA damaged DNA by ABH3 TAS Homo sapiens 15343 R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 15343 R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 15343 R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 15343 R-HSA-449872 https://reactome.org/PathwayBrowser/#/R-HSA-449872 acetaldehyde [cytosolic] => acetaldehyde [mitochondrial] TAS Homo sapiens 15343 R-HSA-5696091 https://reactome.org/PathwayBrowser/#/R-HSA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH TAS Homo sapiens 15343 R-HSA-5696415 https://reactome.org/PathwayBrowser/#/R-HSA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA TAS Homo sapiens 15343 R-HSA-6787321 https://reactome.org/PathwayBrowser/#/R-HSA-6787321 DERA cleaves dR5P to GA3P and CH3CHO TAS Homo sapiens 15343 R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 15343 R-HSA-71707 https://reactome.org/PathwayBrowser/#/R-HSA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ TAS Homo sapiens 15343 R-HSA-71723 https://reactome.org/PathwayBrowser/#/R-HSA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] TAS Homo sapiens 15343 R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 15343 R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 15343 R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 15343 R-MMU-5696091 https://reactome.org/PathwayBrowser/#/R-MMU-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Mus musculus 15343 R-MMU-5696415 https://reactome.org/PathwayBrowser/#/R-MMU-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Mus musculus 15343 R-MMU-6787321 https://reactome.org/PathwayBrowser/#/R-MMU-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Mus musculus 15343 R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 15343 R-MMU-71707 https://reactome.org/PathwayBrowser/#/R-MMU-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Mus musculus 15343 R-MMU-71723 https://reactome.org/PathwayBrowser/#/R-MMU-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Mus musculus 15343 R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 15343 R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 15343 R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 15343 R-RNO-5696091 https://reactome.org/PathwayBrowser/#/R-RNO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Rattus norvegicus 15343 R-RNO-5696415 https://reactome.org/PathwayBrowser/#/R-RNO-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Rattus norvegicus 15343 R-RNO-6787321 https://reactome.org/PathwayBrowser/#/R-RNO-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Rattus norvegicus 15343 R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 15343 R-RNO-71707 https://reactome.org/PathwayBrowser/#/R-RNO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Rattus norvegicus 15343 R-RNO-71723 https://reactome.org/PathwayBrowser/#/R-RNO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Rattus norvegicus 15343 R-SCE-5696091 https://reactome.org/PathwayBrowser/#/R-SCE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Saccharomyces cerevisiae 15343 R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 15343 R-SCE-71707 https://reactome.org/PathwayBrowser/#/R-SCE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Saccharomyces cerevisiae 15343 R-SCE-71723 https://reactome.org/PathwayBrowser/#/R-SCE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Saccharomyces cerevisiae 15343 R-SPO-5696091 https://reactome.org/PathwayBrowser/#/R-SPO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Schizosaccharomyces pombe 15343 R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 15343 R-SPO-71707 https://reactome.org/PathwayBrowser/#/R-SPO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Schizosaccharomyces pombe 15343 R-SPO-71723 https://reactome.org/PathwayBrowser/#/R-SPO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Schizosaccharomyces pombe 15343 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 15343 R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 15343 R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 15343 R-SSC-5696091 https://reactome.org/PathwayBrowser/#/R-SSC-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Sus scrofa 15343 R-SSC-5696415 https://reactome.org/PathwayBrowser/#/R-SSC-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Sus scrofa 15343 R-SSC-6787321 https://reactome.org/PathwayBrowser/#/R-SSC-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Sus scrofa 15343 R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 15343 R-SSC-71707 https://reactome.org/PathwayBrowser/#/R-SSC-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Sus scrofa 15343 R-SSC-71723 https://reactome.org/PathwayBrowser/#/R-SSC-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Sus scrofa 15343 R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 15343 R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 15343 R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 15343 R-XTR-5696091 https://reactome.org/PathwayBrowser/#/R-XTR-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Xenopus tropicalis 15343 R-XTR-5696415 https://reactome.org/PathwayBrowser/#/R-XTR-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Xenopus tropicalis 15343 R-XTR-6787321 https://reactome.org/PathwayBrowser/#/R-XTR-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Xenopus tropicalis 15343 R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 15343 R-XTR-71707 https://reactome.org/PathwayBrowser/#/R-XTR-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Xenopus tropicalis 15343 R-XTR-71723 https://reactome.org/PathwayBrowser/#/R-XTR-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Xenopus tropicalis 15344 R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15344 R-BTA-73912 https://reactome.org/PathwayBrowser/#/R-BTA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Bos taurus 15344 R-BTA-73920 https://reactome.org/PathwayBrowser/#/R-BTA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Bos taurus 15344 R-BTA-74177 https://reactome.org/PathwayBrowser/#/R-BTA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Bos taurus 15344 R-BTA-74180 https://reactome.org/PathwayBrowser/#/R-BTA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Bos taurus 15344 R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15344 R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15344 R-CEL-74177 https://reactome.org/PathwayBrowser/#/R-CEL-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Caenorhabditis elegans 15344 R-CEL-74180 https://reactome.org/PathwayBrowser/#/R-CEL-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Caenorhabditis elegans 15344 R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15344 R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15344 R-CFA-73912 https://reactome.org/PathwayBrowser/#/R-CFA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Canis familiaris 15344 R-CFA-73920 https://reactome.org/PathwayBrowser/#/R-CFA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Canis familiaris 15344 R-CFA-74177 https://reactome.org/PathwayBrowser/#/R-CFA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Canis familiaris 15344 R-CFA-74180 https://reactome.org/PathwayBrowser/#/R-CFA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Canis familiaris 15344 R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15344 R-DDI-74177 https://reactome.org/PathwayBrowser/#/R-DDI-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Dictyostelium discoideum 15344 R-DDI-74180 https://reactome.org/PathwayBrowser/#/R-DDI-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Dictyostelium discoideum 15344 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15344 R-DME-73912 https://reactome.org/PathwayBrowser/#/R-DME-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Drosophila melanogaster 15344 R-DME-73920 https://reactome.org/PathwayBrowser/#/R-DME-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Drosophila melanogaster 15344 R-DME-74177 https://reactome.org/PathwayBrowser/#/R-DME-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Drosophila melanogaster 15344 R-DME-74180 https://reactome.org/PathwayBrowser/#/R-DME-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Drosophila melanogaster 15344 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15344 R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 15344 R-DRE-73912 https://reactome.org/PathwayBrowser/#/R-DRE-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Danio rerio 15344 R-DRE-73920 https://reactome.org/PathwayBrowser/#/R-DRE-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Danio rerio 15344 R-DRE-74177 https://reactome.org/PathwayBrowser/#/R-DRE-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Danio rerio 15344 R-DRE-74180 https://reactome.org/PathwayBrowser/#/R-DRE-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Danio rerio 15344 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15344 R-GGA-73912 https://reactome.org/PathwayBrowser/#/R-GGA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Gallus gallus 15344 R-GGA-73920 https://reactome.org/PathwayBrowser/#/R-GGA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Gallus gallus 15344 R-GGA-74177 https://reactome.org/PathwayBrowser/#/R-GGA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Gallus gallus 15344 R-GGA-74180 https://reactome.org/PathwayBrowser/#/R-GGA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Gallus gallus 15344 R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15344 R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15344 R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15344 R-HSA-73912 https://reactome.org/PathwayBrowser/#/R-HSA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ TAS Homo sapiens 15344 R-HSA-73920 https://reactome.org/PathwayBrowser/#/R-HSA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ TAS Homo sapiens 15344 R-HSA-74177 https://reactome.org/PathwayBrowser/#/R-HSA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA TAS Homo sapiens 15344 R-HSA-74180 https://reactome.org/PathwayBrowser/#/R-HSA-74180 HMG CoA => acetoacetic acid + acetyl CoA TAS Homo sapiens 15344 R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15344 R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15344 R-MMU-73912 https://reactome.org/PathwayBrowser/#/R-MMU-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Mus musculus 15344 R-MMU-73920 https://reactome.org/PathwayBrowser/#/R-MMU-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Mus musculus 15344 R-MMU-74177 https://reactome.org/PathwayBrowser/#/R-MMU-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Mus musculus 15344 R-MMU-74180 https://reactome.org/PathwayBrowser/#/R-MMU-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Mus musculus 15344 R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15344 R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15344 R-RNO-73912 https://reactome.org/PathwayBrowser/#/R-RNO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Rattus norvegicus 15344 R-RNO-73920 https://reactome.org/PathwayBrowser/#/R-RNO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Rattus norvegicus 15344 R-RNO-74177 https://reactome.org/PathwayBrowser/#/R-RNO-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Rattus norvegicus 15344 R-RNO-74180 https://reactome.org/PathwayBrowser/#/R-RNO-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Rattus norvegicus 15344 R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15344 R-SPO-73912 https://reactome.org/PathwayBrowser/#/R-SPO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Schizosaccharomyces pombe 15344 R-SPO-73920 https://reactome.org/PathwayBrowser/#/R-SPO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Schizosaccharomyces pombe 15344 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15344 R-SSC-73912 https://reactome.org/PathwayBrowser/#/R-SSC-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Sus scrofa 15344 R-SSC-73920 https://reactome.org/PathwayBrowser/#/R-SSC-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Sus scrofa 15344 R-SSC-74177 https://reactome.org/PathwayBrowser/#/R-SSC-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Sus scrofa 15344 R-SSC-74180 https://reactome.org/PathwayBrowser/#/R-SSC-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Sus scrofa 15344 R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15344 R-XTR-73912 https://reactome.org/PathwayBrowser/#/R-XTR-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Xenopus tropicalis 15344 R-XTR-73920 https://reactome.org/PathwayBrowser/#/R-XTR-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Xenopus tropicalis 15344 R-XTR-74177 https://reactome.org/PathwayBrowser/#/R-XTR-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Xenopus tropicalis 15344 R-XTR-74180 https://reactome.org/PathwayBrowser/#/R-XTR-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Xenopus tropicalis 15344 R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15354 R-BTA-1483004 https://reactome.org/PathwayBrowser/#/R-BTA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Bos taurus 15354 R-BTA-1483159 https://reactome.org/PathwayBrowser/#/R-BTA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Bos taurus 15354 R-BTA-1483182 https://reactome.org/PathwayBrowser/#/R-BTA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Bos taurus 15354 R-BTA-1483186 https://reactome.org/PathwayBrowser/#/R-BTA-1483186 PC is converted to PS by PTDSS1 IEA Bos taurus 15354 R-BTA-2029471 https://reactome.org/PathwayBrowser/#/R-BTA-2029471 Hydrolysis of PC to PA by PLD IEA Bos taurus 15354 R-BTA-264622 https://reactome.org/PathwayBrowser/#/R-BTA-264622 Cho is acetylated to AcCho by CHAT IEA Bos taurus 15354 R-BTA-429594 https://reactome.org/PathwayBrowser/#/R-BTA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 15354 R-BTA-444433 https://reactome.org/PathwayBrowser/#/R-BTA-444433 Cho transports from the extracellular space to the cytosol IEA Bos taurus 15354 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 15354 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 15354 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 15354 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 15354 R-BTA-6797956 https://reactome.org/PathwayBrowser/#/R-BTA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Bos taurus 15354 R-BTA-6797961 https://reactome.org/PathwayBrowser/#/R-BTA-6797961 CHDH oxidises Cho to BETALD IEA Bos taurus 15354 R-CEL-1483004 https://reactome.org/PathwayBrowser/#/R-CEL-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Caenorhabditis elegans 15354 R-CEL-1483182 https://reactome.org/PathwayBrowser/#/R-CEL-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Caenorhabditis elegans 15354 R-CEL-1483186 https://reactome.org/PathwayBrowser/#/R-CEL-1483186 PC is converted to PS by PTDSS1 IEA Caenorhabditis elegans 15354 R-CEL-2029471 https://reactome.org/PathwayBrowser/#/R-CEL-2029471 Hydrolysis of PC to PA by PLD IEA Caenorhabditis elegans 15354 R-CEL-264622 https://reactome.org/PathwayBrowser/#/R-CEL-264622 Cho is acetylated to AcCho by CHAT IEA Caenorhabditis elegans 15354 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 15354 R-CEL-429594 https://reactome.org/PathwayBrowser/#/R-CEL-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 15354 R-CEL-444433 https://reactome.org/PathwayBrowser/#/R-CEL-444433 Cho transports from the extracellular space to the cytosol IEA Caenorhabditis elegans 15354 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 15354 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 15354 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 15354 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 15354 R-CEL-6797961 https://reactome.org/PathwayBrowser/#/R-CEL-6797961 CHDH oxidises Cho to BETALD IEA Caenorhabditis elegans 15354 R-CFA-1483004 https://reactome.org/PathwayBrowser/#/R-CFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Canis familiaris 15354 R-CFA-1483159 https://reactome.org/PathwayBrowser/#/R-CFA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Canis familiaris 15354 R-CFA-1483182 https://reactome.org/PathwayBrowser/#/R-CFA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Canis familiaris 15354 R-CFA-1483186 https://reactome.org/PathwayBrowser/#/R-CFA-1483186 PC is converted to PS by PTDSS1 IEA Canis familiaris 15354 R-CFA-2029471 https://reactome.org/PathwayBrowser/#/R-CFA-2029471 Hydrolysis of PC to PA by PLD IEA Canis familiaris 15354 R-CFA-264622 https://reactome.org/PathwayBrowser/#/R-CFA-264622 Cho is acetylated to AcCho by CHAT IEA Canis familiaris 15354 R-CFA-429594 https://reactome.org/PathwayBrowser/#/R-CFA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 15354 R-CFA-444433 https://reactome.org/PathwayBrowser/#/R-CFA-444433 Cho transports from the extracellular space to the cytosol IEA Canis familiaris 15354 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 15354 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 15354 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 15354 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 15354 R-CFA-6797956 https://reactome.org/PathwayBrowser/#/R-CFA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Canis familiaris 15354 R-CFA-6797961 https://reactome.org/PathwayBrowser/#/R-CFA-6797961 CHDH oxidises Cho to BETALD IEA Canis familiaris 15354 R-DDI-1483182 https://reactome.org/PathwayBrowser/#/R-DDI-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Dictyostelium discoideum 15354 R-DDI-1483186 https://reactome.org/PathwayBrowser/#/R-DDI-1483186 PC is converted to PS by PTDSS1 IEA Dictyostelium discoideum 15354 R-DDI-2029471 https://reactome.org/PathwayBrowser/#/R-DDI-2029471 Hydrolysis of PC to PA by PLD IEA Dictyostelium discoideum 15354 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 15354 R-DDI-444433 https://reactome.org/PathwayBrowser/#/R-DDI-444433 Cho transports from the extracellular space to the cytosol IEA Dictyostelium discoideum 15354 R-DDI-6797956 https://reactome.org/PathwayBrowser/#/R-DDI-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Dictyostelium discoideum 15354 R-DDI-6797961 https://reactome.org/PathwayBrowser/#/R-DDI-6797961 CHDH oxidises Cho to BETALD IEA Dictyostelium discoideum 15354 R-DME-1483004 https://reactome.org/PathwayBrowser/#/R-DME-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Drosophila melanogaster 15354 R-DME-1483159 https://reactome.org/PathwayBrowser/#/R-DME-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Drosophila melanogaster 15354 R-DME-1483182 https://reactome.org/PathwayBrowser/#/R-DME-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Drosophila melanogaster 15354 R-DME-1483186 https://reactome.org/PathwayBrowser/#/R-DME-1483186 PC is converted to PS by PTDSS1 IEA Drosophila melanogaster 15354 R-DME-2029471 https://reactome.org/PathwayBrowser/#/R-DME-2029471 Hydrolysis of PC to PA by PLD IEA Drosophila melanogaster 15354 R-DME-264622 https://reactome.org/PathwayBrowser/#/R-DME-264622 Cho is acetylated to AcCho by CHAT IEA Drosophila melanogaster 15354 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 15354 R-DME-429594 https://reactome.org/PathwayBrowser/#/R-DME-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 15354 R-DME-444433 https://reactome.org/PathwayBrowser/#/R-DME-444433 Cho transports from the extracellular space to the cytosol IEA Drosophila melanogaster 15354 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 15354 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 15354 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 15354 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 15354 R-DME-6797956 https://reactome.org/PathwayBrowser/#/R-DME-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Drosophila melanogaster 15354 R-DME-6797961 https://reactome.org/PathwayBrowser/#/R-DME-6797961 CHDH oxidises Cho to BETALD IEA Drosophila melanogaster 15354 R-DRE-1483004 https://reactome.org/PathwayBrowser/#/R-DRE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Danio rerio 15354 R-DRE-1483159 https://reactome.org/PathwayBrowser/#/R-DRE-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Danio rerio 15354 R-DRE-1483186 https://reactome.org/PathwayBrowser/#/R-DRE-1483186 PC is converted to PS by PTDSS1 IEA Danio rerio 15354 R-DRE-264622 https://reactome.org/PathwayBrowser/#/R-DRE-264622 Cho is acetylated to AcCho by CHAT IEA Danio rerio 15354 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 15354 R-DRE-444433 https://reactome.org/PathwayBrowser/#/R-DRE-444433 Cho transports from the extracellular space to the cytosol IEA Danio rerio 15354 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 15354 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 15354 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 15354 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 15354 R-GGA-1483004 https://reactome.org/PathwayBrowser/#/R-GGA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Gallus gallus 15354 R-GGA-1483159 https://reactome.org/PathwayBrowser/#/R-GGA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Gallus gallus 15354 R-GGA-1483182 https://reactome.org/PathwayBrowser/#/R-GGA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Gallus gallus 15354 R-GGA-1483186 https://reactome.org/PathwayBrowser/#/R-GGA-1483186 PC is converted to PS by PTDSS1 IEA Gallus gallus 15354 R-GGA-264622 https://reactome.org/PathwayBrowser/#/R-GGA-264622 Cho is acetylated to AcCho by CHAT IEA Gallus gallus 15354 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 15354 R-GGA-429594 https://reactome.org/PathwayBrowser/#/R-GGA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 15354 R-GGA-444433 https://reactome.org/PathwayBrowser/#/R-GGA-444433 Cho transports from the extracellular space to the cytosol IEA Gallus gallus 15354 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 15354 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 15354 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 15354 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 15354 R-GGA-6797956 https://reactome.org/PathwayBrowser/#/R-GGA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Gallus gallus 15354 R-GGA-6797961 https://reactome.org/PathwayBrowser/#/R-GGA-6797961 CHDH oxidises Cho to BETALD IEA Gallus gallus 15354 R-HSA-1483004 https://reactome.org/PathwayBrowser/#/R-HSA-1483004 Cho is phosphorylated to PCho by CHK dimer TAS Homo sapiens 15354 R-HSA-1483116 https://reactome.org/PathwayBrowser/#/R-HSA-1483116 GPCho is hydrolyzed to Cho and G3P by GPCPD1 IEA Homo sapiens 15354 R-HSA-1483142 https://reactome.org/PathwayBrowser/#/R-HSA-1483142 PC is transphosphatidylated to PG by PLD1-4/6 IEA Homo sapiens 15354 R-HSA-1483159 https://reactome.org/PathwayBrowser/#/R-HSA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 TAS Homo sapiens 15354 R-HSA-1483182 https://reactome.org/PathwayBrowser/#/R-HSA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 TAS Homo sapiens 15354 R-HSA-1483186 https://reactome.org/PathwayBrowser/#/R-HSA-1483186 PC is converted to PS by PTDSS1 TAS Homo sapiens 15354 R-HSA-2029471 https://reactome.org/PathwayBrowser/#/R-HSA-2029471 Hydrolysis of PC to PA by PLD TAS Homo sapiens 15354 R-HSA-264622 https://reactome.org/PathwayBrowser/#/R-HSA-264622 Cho is acetylated to AcCho by CHAT TAS Homo sapiens 15354 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 15354 R-HSA-429594 https://reactome.org/PathwayBrowser/#/R-HSA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 15354 R-HSA-444433 https://reactome.org/PathwayBrowser/#/R-HSA-444433 Cho transports from the extracellular space to the cytosol TAS Homo sapiens 15354 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 15354 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 15354 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 15354 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 15354 R-HSA-5658483 https://reactome.org/PathwayBrowser/#/R-HSA-5658483 Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 15354 R-HSA-6797956 https://reactome.org/PathwayBrowser/#/R-HSA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix TAS Homo sapiens 15354 R-HSA-6797961 https://reactome.org/PathwayBrowser/#/R-HSA-6797961 CHDH oxidises Cho to BETALD TAS Homo sapiens 15354 R-HSA-6814132 https://reactome.org/PathwayBrowser/#/R-HSA-6814132 GDPD5 hydrolyzes GPCho IEA Homo sapiens 15354 R-MMU-1483004 https://reactome.org/PathwayBrowser/#/R-MMU-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Mus musculus 15354 R-MMU-1483112 https://reactome.org/PathwayBrowser/#/R-MMU-1483112 GPCho is hydrolyzed to Cho and G3P by Gpcpd1 TAS Mus musculus 15354 R-MMU-1483159 https://reactome.org/PathwayBrowser/#/R-MMU-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Mus musculus 15354 R-MMU-1483172 https://reactome.org/PathwayBrowser/#/R-MMU-1483172 PC is transphosphatidylated to PG by Pld1-4/6 TAS Mus musculus 15354 R-MMU-1483182 https://reactome.org/PathwayBrowser/#/R-MMU-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Mus musculus 15354 R-MMU-1483186 https://reactome.org/PathwayBrowser/#/R-MMU-1483186 PC is converted to PS by PTDSS1 IEA Mus musculus 15354 R-MMU-2029471 https://reactome.org/PathwayBrowser/#/R-MMU-2029471 Hydrolysis of PC to PA by PLD IEA Mus musculus 15354 R-MMU-264622 https://reactome.org/PathwayBrowser/#/R-MMU-264622 Cho is acetylated to AcCho by CHAT IEA Mus musculus 15354 R-MMU-429594 https://reactome.org/PathwayBrowser/#/R-MMU-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 15354 R-MMU-444433 https://reactome.org/PathwayBrowser/#/R-MMU-444433 Cho transports from the extracellular space to the cytosol IEA Mus musculus 15354 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 15354 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 15354 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 15354 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 15354 R-MMU-6797956 https://reactome.org/PathwayBrowser/#/R-MMU-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Mus musculus 15354 R-MMU-6797961 https://reactome.org/PathwayBrowser/#/R-MMU-6797961 CHDH oxidises Cho to BETALD IEA Mus musculus 15354 R-MMU-6814137 https://reactome.org/PathwayBrowser/#/R-MMU-6814137 Gdpd5 hydrolyzes GPCho TAS Mus musculus 15354 R-PFA-1483004 https://reactome.org/PathwayBrowser/#/R-PFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Plasmodium falciparum 15354 R-PFA-1483186 https://reactome.org/PathwayBrowser/#/R-PFA-1483186 PC is converted to PS by PTDSS1 IEA Plasmodium falciparum 15354 R-PFA-444433 https://reactome.org/PathwayBrowser/#/R-PFA-444433 Cho transports from the extracellular space to the cytosol IEA Plasmodium falciparum 15354 R-PFA-6797956 https://reactome.org/PathwayBrowser/#/R-PFA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Plasmodium falciparum 15354 R-RNO-1483004 https://reactome.org/PathwayBrowser/#/R-RNO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Rattus norvegicus 15354 R-RNO-1483159 https://reactome.org/PathwayBrowser/#/R-RNO-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Rattus norvegicus 15354 R-RNO-1483182 https://reactome.org/PathwayBrowser/#/R-RNO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Rattus norvegicus 15354 R-RNO-1483186 https://reactome.org/PathwayBrowser/#/R-RNO-1483186 PC is converted to PS by PTDSS1 IEA Rattus norvegicus 15354 R-RNO-2029471 https://reactome.org/PathwayBrowser/#/R-RNO-2029471 Hydrolysis of PC to PA by PLD IEA Rattus norvegicus 15354 R-RNO-264622 https://reactome.org/PathwayBrowser/#/R-RNO-264622 Cho is acetylated to AcCho by CHAT IEA Rattus norvegicus 15354 R-RNO-429594 https://reactome.org/PathwayBrowser/#/R-RNO-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 15354 R-RNO-444433 https://reactome.org/PathwayBrowser/#/R-RNO-444433 Cho transports from the extracellular space to the cytosol IEA Rattus norvegicus 15354 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 15354 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 15354 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 15354 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 15354 R-RNO-6797956 https://reactome.org/PathwayBrowser/#/R-RNO-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Rattus norvegicus 15354 R-RNO-6797961 https://reactome.org/PathwayBrowser/#/R-RNO-6797961 CHDH oxidises Cho to BETALD IEA Rattus norvegicus 15354 R-SCE-1483004 https://reactome.org/PathwayBrowser/#/R-SCE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Saccharomyces cerevisiae 15354 R-SCE-1483182 https://reactome.org/PathwayBrowser/#/R-SCE-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Saccharomyces cerevisiae 15354 R-SCE-2029471 https://reactome.org/PathwayBrowser/#/R-SCE-2029471 Hydrolysis of PC to PA by PLD IEA Saccharomyces cerevisiae 15354 R-SPO-1483004 https://reactome.org/PathwayBrowser/#/R-SPO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Schizosaccharomyces pombe 15354 R-SPO-1483182 https://reactome.org/PathwayBrowser/#/R-SPO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Schizosaccharomyces pombe 15354 R-SPO-2029471 https://reactome.org/PathwayBrowser/#/R-SPO-2029471 Hydrolysis of PC to PA by PLD IEA Schizosaccharomyces pombe 15354 R-SSC-1483004 https://reactome.org/PathwayBrowser/#/R-SSC-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Sus scrofa 15354 R-SSC-1483159 https://reactome.org/PathwayBrowser/#/R-SSC-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Sus scrofa 15354 R-SSC-1483182 https://reactome.org/PathwayBrowser/#/R-SSC-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Sus scrofa 15354 R-SSC-1483186 https://reactome.org/PathwayBrowser/#/R-SSC-1483186 PC is converted to PS by PTDSS1 IEA Sus scrofa 15354 R-SSC-2029471 https://reactome.org/PathwayBrowser/#/R-SSC-2029471 Hydrolysis of PC to PA by PLD IEA Sus scrofa 15354 R-SSC-264622 https://reactome.org/PathwayBrowser/#/R-SSC-264622 Cho is acetylated to AcCho by CHAT IEA Sus scrofa 15354 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 15354 R-SSC-429594 https://reactome.org/PathwayBrowser/#/R-SSC-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 15354 R-SSC-444433 https://reactome.org/PathwayBrowser/#/R-SSC-444433 Cho transports from the extracellular space to the cytosol IEA Sus scrofa 15354 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 15354 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 15354 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 15354 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 15354 R-SSC-6797956 https://reactome.org/PathwayBrowser/#/R-SSC-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Sus scrofa 15354 R-SSC-6797961 https://reactome.org/PathwayBrowser/#/R-SSC-6797961 CHDH oxidises Cho to BETALD IEA Sus scrofa 15354 R-XTR-1483004 https://reactome.org/PathwayBrowser/#/R-XTR-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Xenopus tropicalis 15354 R-XTR-1483159 https://reactome.org/PathwayBrowser/#/R-XTR-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Xenopus tropicalis 15354 R-XTR-1483182 https://reactome.org/PathwayBrowser/#/R-XTR-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Xenopus tropicalis 15354 R-XTR-1483186 https://reactome.org/PathwayBrowser/#/R-XTR-1483186 PC is converted to PS by PTDSS1 IEA Xenopus tropicalis 15354 R-XTR-2029471 https://reactome.org/PathwayBrowser/#/R-XTR-2029471 Hydrolysis of PC to PA by PLD IEA Xenopus tropicalis 15354 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 15354 R-XTR-429594 https://reactome.org/PathwayBrowser/#/R-XTR-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 15354 R-XTR-444433 https://reactome.org/PathwayBrowser/#/R-XTR-444433 Cho transports from the extracellular space to the cytosol IEA Xenopus tropicalis 15354 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 15354 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 15354 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 15354 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 15354 R-XTR-6797956 https://reactome.org/PathwayBrowser/#/R-XTR-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Xenopus tropicalis 15355 R-BTA-264615 https://reactome.org/PathwayBrowser/#/R-BTA-264615 Loading of acetylcholine in synaptic vesicles IEA Bos taurus 15355 R-BTA-264622 https://reactome.org/PathwayBrowser/#/R-BTA-264622 Cho is acetylated to AcCho by CHAT IEA Bos taurus 15355 R-BTA-372505 https://reactome.org/PathwayBrowser/#/R-BTA-372505 Acetylcholine synaptic vesicle docking and priming IEA Bos taurus 15355 R-BTA-372529 https://reactome.org/PathwayBrowser/#/R-BTA-372529 Release of acetylcholine at the synapse IEA Bos taurus 15355 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15355 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 15355 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 15355 R-BTA-390649 https://reactome.org/PathwayBrowser/#/R-BTA-390649 CHRM1,3,5 bind acetylcholine IEA Bos taurus 15355 R-BTA-390673 https://reactome.org/PathwayBrowser/#/R-BTA-390673 CHRM2,4 bind acetylcholine IEA Bos taurus 15355 R-BTA-622325 https://reactome.org/PathwayBrowser/#/R-BTA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 15355 R-BTA-622326 https://reactome.org/PathwayBrowser/#/R-BTA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Bos taurus 15355 R-BTA-629588 https://reactome.org/PathwayBrowser/#/R-BTA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Bos taurus 15355 R-BTA-629595 https://reactome.org/PathwayBrowser/#/R-BTA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 15355 R-BTA-629596 https://reactome.org/PathwayBrowser/#/R-BTA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 15355 R-BTA-629599 https://reactome.org/PathwayBrowser/#/R-BTA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Bos taurus 15355 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15355 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15355 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 15355 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 15355 R-CEL-264615 https://reactome.org/PathwayBrowser/#/R-CEL-264615 Loading of acetylcholine in synaptic vesicles IEA Caenorhabditis elegans 15355 R-CEL-264622 https://reactome.org/PathwayBrowser/#/R-CEL-264622 Cho is acetylated to AcCho by CHAT IEA Caenorhabditis elegans 15355 R-CEL-372505 https://reactome.org/PathwayBrowser/#/R-CEL-372505 Acetylcholine synaptic vesicle docking and priming IEA Caenorhabditis elegans 15355 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 15355 R-CEL-372529 https://reactome.org/PathwayBrowser/#/R-CEL-372529 Release of acetylcholine at the synapse IEA Caenorhabditis elegans 15355 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 15355 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 15355 R-CEL-390649 https://reactome.org/PathwayBrowser/#/R-CEL-390649 CHRM1,3,5 bind acetylcholine IEA Caenorhabditis elegans 15355 R-CEL-390673 https://reactome.org/PathwayBrowser/#/R-CEL-390673 CHRM2,4 bind acetylcholine IEA Caenorhabditis elegans 15355 R-CEL-622325 https://reactome.org/PathwayBrowser/#/R-CEL-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 15355 R-CEL-622326 https://reactome.org/PathwayBrowser/#/R-CEL-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Caenorhabditis elegans 15355 R-CEL-629588 https://reactome.org/PathwayBrowser/#/R-CEL-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Caenorhabditis elegans 15355 R-CEL-629595 https://reactome.org/PathwayBrowser/#/R-CEL-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 15355 R-CEL-629596 https://reactome.org/PathwayBrowser/#/R-CEL-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 15355 R-CEL-629599 https://reactome.org/PathwayBrowser/#/R-CEL-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Caenorhabditis elegans 15355 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 15355 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15355 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 15355 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 15355 R-CFA-264615 https://reactome.org/PathwayBrowser/#/R-CFA-264615 Loading of acetylcholine in synaptic vesicles IEA Canis familiaris 15355 R-CFA-264622 https://reactome.org/PathwayBrowser/#/R-CFA-264622 Cho is acetylated to AcCho by CHAT IEA Canis familiaris 15355 R-CFA-372505 https://reactome.org/PathwayBrowser/#/R-CFA-372505 Acetylcholine synaptic vesicle docking and priming IEA Canis familiaris 15355 R-CFA-372529 https://reactome.org/PathwayBrowser/#/R-CFA-372529 Release of acetylcholine at the synapse IEA Canis familiaris 15355 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15355 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 15355 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 15355 R-CFA-390649 https://reactome.org/PathwayBrowser/#/R-CFA-390649 CHRM1,3,5 bind acetylcholine IEA Canis familiaris 15355 R-CFA-390673 https://reactome.org/PathwayBrowser/#/R-CFA-390673 CHRM2,4 bind acetylcholine IEA Canis familiaris 15355 R-CFA-622325 https://reactome.org/PathwayBrowser/#/R-CFA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 15355 R-CFA-622326 https://reactome.org/PathwayBrowser/#/R-CFA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Canis familiaris 15355 R-CFA-629588 https://reactome.org/PathwayBrowser/#/R-CFA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Canis familiaris 15355 R-CFA-629595 https://reactome.org/PathwayBrowser/#/R-CFA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 15355 R-CFA-629596 https://reactome.org/PathwayBrowser/#/R-CFA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 15355 R-CFA-629599 https://reactome.org/PathwayBrowser/#/R-CFA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Canis familiaris 15355 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15355 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15355 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 15355 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 15355 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 15355 R-DME-264615 https://reactome.org/PathwayBrowser/#/R-DME-264615 Loading of acetylcholine in synaptic vesicles IEA Drosophila melanogaster 15355 R-DME-264622 https://reactome.org/PathwayBrowser/#/R-DME-264622 Cho is acetylated to AcCho by CHAT IEA Drosophila melanogaster 15355 R-DME-372505 https://reactome.org/PathwayBrowser/#/R-DME-372505 Acetylcholine synaptic vesicle docking and priming IEA Drosophila melanogaster 15355 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 15355 R-DME-372529 https://reactome.org/PathwayBrowser/#/R-DME-372529 Release of acetylcholine at the synapse IEA Drosophila melanogaster 15355 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 15355 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 15355 R-DME-390649 https://reactome.org/PathwayBrowser/#/R-DME-390649 CHRM1,3,5 bind acetylcholine IEA Drosophila melanogaster 15355 R-DME-390673 https://reactome.org/PathwayBrowser/#/R-DME-390673 CHRM2,4 bind acetylcholine IEA Drosophila melanogaster 15355 R-DME-622325 https://reactome.org/PathwayBrowser/#/R-DME-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 15355 R-DME-622326 https://reactome.org/PathwayBrowser/#/R-DME-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Drosophila melanogaster 15355 R-DME-629588 https://reactome.org/PathwayBrowser/#/R-DME-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Drosophila melanogaster 15355 R-DME-629595 https://reactome.org/PathwayBrowser/#/R-DME-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 15355 R-DME-629596 https://reactome.org/PathwayBrowser/#/R-DME-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 15355 R-DME-629599 https://reactome.org/PathwayBrowser/#/R-DME-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Drosophila melanogaster 15355 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 15355 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15355 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 15355 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 15355 R-DRE-264615 https://reactome.org/PathwayBrowser/#/R-DRE-264615 Loading of acetylcholine in synaptic vesicles IEA Danio rerio 15355 R-DRE-264622 https://reactome.org/PathwayBrowser/#/R-DRE-264622 Cho is acetylated to AcCho by CHAT IEA Danio rerio 15355 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 15355 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 15355 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 15355 R-DRE-390649 https://reactome.org/PathwayBrowser/#/R-DRE-390649 CHRM1,3,5 bind acetylcholine IEA Danio rerio 15355 R-DRE-390673 https://reactome.org/PathwayBrowser/#/R-DRE-390673 CHRM2,4 bind acetylcholine IEA Danio rerio 15355 R-DRE-622326 https://reactome.org/PathwayBrowser/#/R-DRE-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Danio rerio 15355 R-DRE-629595 https://reactome.org/PathwayBrowser/#/R-DRE-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Danio rerio 15355 R-DRE-629596 https://reactome.org/PathwayBrowser/#/R-DRE-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Danio rerio 15355 R-DRE-629599 https://reactome.org/PathwayBrowser/#/R-DRE-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Danio rerio 15355 R-GGA-264615 https://reactome.org/PathwayBrowser/#/R-GGA-264615 Loading of acetylcholine in synaptic vesicles IEA Gallus gallus 15355 R-GGA-264622 https://reactome.org/PathwayBrowser/#/R-GGA-264622 Cho is acetylated to AcCho by CHAT IEA Gallus gallus 15355 R-GGA-372505 https://reactome.org/PathwayBrowser/#/R-GGA-372505 Acetylcholine synaptic vesicle docking and priming IEA Gallus gallus 15355 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 15355 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 15355 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 15355 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 15355 R-GGA-390649 https://reactome.org/PathwayBrowser/#/R-GGA-390649 CHRM1,3,5 bind acetylcholine IEA Gallus gallus 15355 R-GGA-390673 https://reactome.org/PathwayBrowser/#/R-GGA-390673 CHRM2,4 bind acetylcholine IEA Gallus gallus 15355 R-GGA-622325 https://reactome.org/PathwayBrowser/#/R-GGA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 15355 R-GGA-622326 https://reactome.org/PathwayBrowser/#/R-GGA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Gallus gallus 15355 R-GGA-629588 https://reactome.org/PathwayBrowser/#/R-GGA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Gallus gallus 15355 R-GGA-629595 https://reactome.org/PathwayBrowser/#/R-GGA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 15355 R-GGA-629596 https://reactome.org/PathwayBrowser/#/R-GGA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 15355 R-GGA-629599 https://reactome.org/PathwayBrowser/#/R-GGA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Gallus gallus 15355 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 15355 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15355 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 15355 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 15355 R-HSA-264615 https://reactome.org/PathwayBrowser/#/R-HSA-264615 Loading of acetylcholine in synaptic vesicles TAS Homo sapiens 15355 R-HSA-264622 https://reactome.org/PathwayBrowser/#/R-HSA-264622 Cho is acetylated to AcCho by CHAT TAS Homo sapiens 15355 R-HSA-372505 https://reactome.org/PathwayBrowser/#/R-HSA-372505 Acetylcholine synaptic vesicle docking and priming TAS Homo sapiens 15355 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 15355 R-HSA-372529 https://reactome.org/PathwayBrowser/#/R-HSA-372529 Release of acetylcholine at the synapse TAS Homo sapiens 15355 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15355 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 15355 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 15355 R-HSA-390649 https://reactome.org/PathwayBrowser/#/R-HSA-390649 CHRM1,3,5 bind acetylcholine TAS Homo sapiens 15355 R-HSA-390673 https://reactome.org/PathwayBrowser/#/R-HSA-390673 CHRM2,4 bind acetylcholine TAS Homo sapiens 15355 R-HSA-399995 https://reactome.org/PathwayBrowser/#/R-HSA-399995 Muscarinic Acetylcholine Receptor M3 activates Gq IEA Homo sapiens 15355 R-HSA-400012 https://reactome.org/PathwayBrowser/#/R-HSA-400012 Acetylcholine binds Muscarinic Acetylcholine Receptor M3 IEA Homo sapiens 15355 R-HSA-622325 https://reactome.org/PathwayBrowser/#/R-HSA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 15355 R-HSA-622326 https://reactome.org/PathwayBrowser/#/R-HSA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors TAS Homo sapiens 15355 R-HSA-629588 https://reactome.org/PathwayBrowser/#/R-HSA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors TAS Homo sapiens 15355 R-HSA-629595 https://reactome.org/PathwayBrowser/#/R-HSA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 15355 R-HSA-629596 https://reactome.org/PathwayBrowser/#/R-HSA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 15355 R-HSA-629599 https://reactome.org/PathwayBrowser/#/R-HSA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors TAS Homo sapiens 15355 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15355 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15355 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 15355 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 15355 R-HSA-9663736 https://reactome.org/PathwayBrowser/#/R-HSA-9663736 CHRNA9:CHRNA10 binds acetylcholine IEA Homo sapiens 15355 R-HSA-9663785 https://reactome.org/PathwayBrowser/#/R-HSA-9663785 CHRNA9:CHRNA10:AcCho transports Ca2+ from the extracellular region to the cytosol IEA Homo sapiens 15355 R-MMU-264615 https://reactome.org/PathwayBrowser/#/R-MMU-264615 Loading of acetylcholine in synaptic vesicles IEA Mus musculus 15355 R-MMU-264622 https://reactome.org/PathwayBrowser/#/R-MMU-264622 Cho is acetylated to AcCho by CHAT IEA Mus musculus 15355 R-MMU-372505 https://reactome.org/PathwayBrowser/#/R-MMU-372505 Acetylcholine synaptic vesicle docking and priming IEA Mus musculus 15355 R-MMU-372529 https://reactome.org/PathwayBrowser/#/R-MMU-372529 Release of acetylcholine at the synapse IEA Mus musculus 15355 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15355 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 15355 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 15355 R-MMU-390649 https://reactome.org/PathwayBrowser/#/R-MMU-390649 CHRM1,3,5 bind acetylcholine IEA Mus musculus 15355 R-MMU-390673 https://reactome.org/PathwayBrowser/#/R-MMU-390673 CHRM2,4 bind acetylcholine IEA Mus musculus 15355 R-MMU-426547 https://reactome.org/PathwayBrowser/#/R-MMU-426547 Activation of Gq by Muscarinic Acetylcholine Receptor M3 TAS Mus musculus 15355 R-MMU-426560 https://reactome.org/PathwayBrowser/#/R-MMU-426560 Binding of Acetylcholine by Muscarinic Acetylcholine Receptor M3 TAS Mus musculus 15355 R-MMU-622325 https://reactome.org/PathwayBrowser/#/R-MMU-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 15355 R-MMU-622326 https://reactome.org/PathwayBrowser/#/R-MMU-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Mus musculus 15355 R-MMU-629588 https://reactome.org/PathwayBrowser/#/R-MMU-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Mus musculus 15355 R-MMU-629595 https://reactome.org/PathwayBrowser/#/R-MMU-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 15355 R-MMU-629596 https://reactome.org/PathwayBrowser/#/R-MMU-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 15355 R-MMU-629599 https://reactome.org/PathwayBrowser/#/R-MMU-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Mus musculus 15355 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15355 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15355 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 15355 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 15355 R-RNO-264615 https://reactome.org/PathwayBrowser/#/R-RNO-264615 Loading of acetylcholine in synaptic vesicles IEA Rattus norvegicus 15355 R-RNO-264622 https://reactome.org/PathwayBrowser/#/R-RNO-264622 Cho is acetylated to AcCho by CHAT IEA Rattus norvegicus 15355 R-RNO-372505 https://reactome.org/PathwayBrowser/#/R-RNO-372505 Acetylcholine synaptic vesicle docking and priming IEA Rattus norvegicus 15355 R-RNO-372529 https://reactome.org/PathwayBrowser/#/R-RNO-372529 Release of acetylcholine at the synapse IEA Rattus norvegicus 15355 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15355 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 15355 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 15355 R-RNO-390649 https://reactome.org/PathwayBrowser/#/R-RNO-390649 CHRM1,3,5 bind acetylcholine IEA Rattus norvegicus 15355 R-RNO-390673 https://reactome.org/PathwayBrowser/#/R-RNO-390673 CHRM2,4 bind acetylcholine IEA Rattus norvegicus 15355 R-RNO-622325 https://reactome.org/PathwayBrowser/#/R-RNO-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 15355 R-RNO-622326 https://reactome.org/PathwayBrowser/#/R-RNO-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Rattus norvegicus 15355 R-RNO-629588 https://reactome.org/PathwayBrowser/#/R-RNO-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Rattus norvegicus 15355 R-RNO-629595 https://reactome.org/PathwayBrowser/#/R-RNO-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 15355 R-RNO-629596 https://reactome.org/PathwayBrowser/#/R-RNO-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 15355 R-RNO-629599 https://reactome.org/PathwayBrowser/#/R-RNO-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Rattus norvegicus 15355 R-RNO-9667850 https://reactome.org/PathwayBrowser/#/R-RNO-9667850 Chrna9:Chrna10:AcCho transports calcium ions from the extracellular region to the cytosol TAS Rattus norvegicus 15355 R-RNO-9667857 https://reactome.org/PathwayBrowser/#/R-RNO-9667857 Chrna9:Chrna10 binds acetylcholine (AcCho) TAS Rattus norvegicus 15355 R-SSC-264615 https://reactome.org/PathwayBrowser/#/R-SSC-264615 Loading of acetylcholine in synaptic vesicles IEA Sus scrofa 15355 R-SSC-264622 https://reactome.org/PathwayBrowser/#/R-SSC-264622 Cho is acetylated to AcCho by CHAT IEA Sus scrofa 15355 R-SSC-372505 https://reactome.org/PathwayBrowser/#/R-SSC-372505 Acetylcholine synaptic vesicle docking and priming IEA Sus scrofa 15355 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 15355 R-SSC-372529 https://reactome.org/PathwayBrowser/#/R-SSC-372529 Release of acetylcholine at the synapse IEA Sus scrofa 15355 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15355 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 15355 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 15355 R-SSC-390649 https://reactome.org/PathwayBrowser/#/R-SSC-390649 CHRM1,3,5 bind acetylcholine IEA Sus scrofa 15355 R-SSC-390673 https://reactome.org/PathwayBrowser/#/R-SSC-390673 CHRM2,4 bind acetylcholine IEA Sus scrofa 15355 R-SSC-622326 https://reactome.org/PathwayBrowser/#/R-SSC-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Sus scrofa 15355 R-SSC-629595 https://reactome.org/PathwayBrowser/#/R-SSC-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa 15355 R-SSC-629596 https://reactome.org/PathwayBrowser/#/R-SSC-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa 15355 R-SSC-629599 https://reactome.org/PathwayBrowser/#/R-SSC-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Sus scrofa 15355 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15355 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15355 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 15355 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 15355 R-XTR-264615 https://reactome.org/PathwayBrowser/#/R-XTR-264615 Loading of acetylcholine in synaptic vesicles IEA Xenopus tropicalis 15355 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 15355 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 15355 R-XTR-383313 https://reactome.org/PathwayBrowser/#/R-XTR-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Xenopus tropicalis 15355 R-XTR-390649 https://reactome.org/PathwayBrowser/#/R-XTR-390649 CHRM1,3,5 bind acetylcholine IEA Xenopus tropicalis 15355 R-XTR-390673 https://reactome.org/PathwayBrowser/#/R-XTR-390673 CHRM2,4 bind acetylcholine IEA Xenopus tropicalis 15355 R-XTR-622325 https://reactome.org/PathwayBrowser/#/R-XTR-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 15355 R-XTR-622326 https://reactome.org/PathwayBrowser/#/R-XTR-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Xenopus tropicalis 15355 R-XTR-629588 https://reactome.org/PathwayBrowser/#/R-XTR-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Xenopus tropicalis 15355 R-XTR-629595 https://reactome.org/PathwayBrowser/#/R-XTR-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 15355 R-XTR-629596 https://reactome.org/PathwayBrowser/#/R-XTR-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 15355 R-XTR-629599 https://reactome.org/PathwayBrowser/#/R-XTR-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Xenopus tropicalis 15355 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 15355 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15355 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 15355 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 15361 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 15361 R-BTA-389684 https://reactome.org/PathwayBrowser/#/R-BTA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Bos taurus 15361 R-BTA-4085217 https://reactome.org/PathwayBrowser/#/R-BTA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Bos taurus 15361 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Bos taurus 15361 R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15361 R-BTA-507749 https://reactome.org/PathwayBrowser/#/R-BTA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Bos taurus 15361 R-BTA-507775 https://reactome.org/PathwayBrowser/#/R-BTA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Bos taurus 15361 R-BTA-6784423 https://reactome.org/PathwayBrowser/#/R-BTA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Bos taurus 15361 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 15361 R-BTA-70510 https://reactome.org/PathwayBrowser/#/R-BTA-70510 LDH tetramer oxidises LACT to PYR IEA Bos taurus 15361 R-BTA-70523 https://reactome.org/PathwayBrowser/#/R-BTA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Bos taurus 15361 R-BTA-70524 https://reactome.org/PathwayBrowser/#/R-BTA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Bos taurus 15361 R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 15361 R-BTA-71849 https://reactome.org/PathwayBrowser/#/R-BTA-71849 LDH tetramer reduces PYR to LACT IEA Bos taurus 15361 R-BTA-8876312 https://reactome.org/PathwayBrowser/#/R-BTA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Bos taurus 15361 R-BTA-893593 https://reactome.org/PathwayBrowser/#/R-BTA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Bos taurus 15361 R-BTA-893596 https://reactome.org/PathwayBrowser/#/R-BTA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Bos taurus 15361 R-BTA-893616 https://reactome.org/PathwayBrowser/#/R-BTA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Bos taurus 15361 R-BTA-9012016 https://reactome.org/PathwayBrowser/#/R-BTA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Bos taurus 15361 R-BTA-9012036 https://reactome.org/PathwayBrowser/#/R-BTA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Bos taurus 15361 R-BTA-9012268 https://reactome.org/PathwayBrowser/#/R-BTA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Bos taurus 15361 R-BTA-9012349 https://reactome.org/PathwayBrowser/#/R-BTA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Bos taurus 15361 R-BTA-9012374 https://reactome.org/PathwayBrowser/#/R-BTA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Bos taurus 15361 R-BTA-9012721 https://reactome.org/PathwayBrowser/#/R-BTA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Bos taurus 15361 R-BTA-9013471 https://reactome.org/PathwayBrowser/#/R-BTA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Bos taurus 15361 R-BTA-9013533 https://reactome.org/PathwayBrowser/#/R-BTA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Bos taurus 15361 R-BTA-9014741 https://reactome.org/PathwayBrowser/#/R-BTA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Bos taurus 15361 R-BTA-9034539 https://reactome.org/PathwayBrowser/#/R-BTA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Bos taurus 15361 R-BTA-9034756 https://reactome.org/PathwayBrowser/#/R-BTA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Bos taurus 15361 R-BTA-904864 https://reactome.org/PathwayBrowser/#/R-BTA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Bos taurus 15361 R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15361 R-BTA-9861660 https://reactome.org/PathwayBrowser/#/R-BTA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Bos taurus 15361 R-BTA-9861734 https://reactome.org/PathwayBrowser/#/R-BTA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Bos taurus 15361 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 15361 R-CEL-389684 https://reactome.org/PathwayBrowser/#/R-CEL-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Caenorhabditis elegans 15361 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-CEL-507749 https://reactome.org/PathwayBrowser/#/R-CEL-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Caenorhabditis elegans 15361 R-CEL-507775 https://reactome.org/PathwayBrowser/#/R-CEL-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Caenorhabditis elegans 15361 R-CEL-6807826 https://reactome.org/PathwayBrowser/#/R-CEL-6807826 LDHAL6B reduces PYR to LACT IEA Caenorhabditis elegans 15361 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 15361 R-CEL-70510 https://reactome.org/PathwayBrowser/#/R-CEL-70510 LDH tetramer oxidises LACT to PYR IEA Caenorhabditis elegans 15361 R-CEL-70523 https://reactome.org/PathwayBrowser/#/R-CEL-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Caenorhabditis elegans 15361 R-CEL-70524 https://reactome.org/PathwayBrowser/#/R-CEL-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Caenorhabditis elegans 15361 R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 15361 R-CEL-71849 https://reactome.org/PathwayBrowser/#/R-CEL-71849 LDH tetramer reduces PYR to LACT IEA Caenorhabditis elegans 15361 R-CEL-8876312 https://reactome.org/PathwayBrowser/#/R-CEL-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-CEL-893593 https://reactome.org/PathwayBrowser/#/R-CEL-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Caenorhabditis elegans 15361 R-CEL-893596 https://reactome.org/PathwayBrowser/#/R-CEL-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Caenorhabditis elegans 15361 R-CEL-893616 https://reactome.org/PathwayBrowser/#/R-CEL-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Caenorhabditis elegans 15361 R-CEL-9012016 https://reactome.org/PathwayBrowser/#/R-CEL-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Caenorhabditis elegans 15361 R-CEL-9012036 https://reactome.org/PathwayBrowser/#/R-CEL-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 15361 R-CEL-9012268 https://reactome.org/PathwayBrowser/#/R-CEL-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 15361 R-CEL-9012349 https://reactome.org/PathwayBrowser/#/R-CEL-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 15361 R-CEL-9012374 https://reactome.org/PathwayBrowser/#/R-CEL-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Caenorhabditis elegans 15361 R-CEL-9012721 https://reactome.org/PathwayBrowser/#/R-CEL-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Caenorhabditis elegans 15361 R-CEL-9013471 https://reactome.org/PathwayBrowser/#/R-CEL-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Caenorhabditis elegans 15361 R-CEL-9013533 https://reactome.org/PathwayBrowser/#/R-CEL-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Caenorhabditis elegans 15361 R-CEL-9014741 https://reactome.org/PathwayBrowser/#/R-CEL-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Caenorhabditis elegans 15361 R-CEL-9034539 https://reactome.org/PathwayBrowser/#/R-CEL-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Caenorhabditis elegans 15361 R-CEL-9034756 https://reactome.org/PathwayBrowser/#/R-CEL-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Caenorhabditis elegans 15361 R-CEL-904864 https://reactome.org/PathwayBrowser/#/R-CEL-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Caenorhabditis elegans 15361 R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-CEL-9861660 https://reactome.org/PathwayBrowser/#/R-CEL-9861660 ME1 tetramer decarboxylates OA to PYR IEA Caenorhabditis elegans 15361 R-CEL-9861734 https://reactome.org/PathwayBrowser/#/R-CEL-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Caenorhabditis elegans 15361 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 15361 R-CFA-389684 https://reactome.org/PathwayBrowser/#/R-CFA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Canis familiaris 15361 R-CFA-4085217 https://reactome.org/PathwayBrowser/#/R-CFA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Canis familiaris 15361 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Canis familiaris 15361 R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15361 R-CFA-507749 https://reactome.org/PathwayBrowser/#/R-CFA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Canis familiaris 15361 R-CFA-507775 https://reactome.org/PathwayBrowser/#/R-CFA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Canis familiaris 15361 R-CFA-6784423 https://reactome.org/PathwayBrowser/#/R-CFA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Canis familiaris 15361 R-CFA-6807826 https://reactome.org/PathwayBrowser/#/R-CFA-6807826 LDHAL6B reduces PYR to LACT IEA Canis familiaris 15361 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 15361 R-CFA-70510 https://reactome.org/PathwayBrowser/#/R-CFA-70510 LDH tetramer oxidises LACT to PYR IEA Canis familiaris 15361 R-CFA-70523 https://reactome.org/PathwayBrowser/#/R-CFA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Canis familiaris 15361 R-CFA-70524 https://reactome.org/PathwayBrowser/#/R-CFA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Canis familiaris 15361 R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 15361 R-CFA-71849 https://reactome.org/PathwayBrowser/#/R-CFA-71849 LDH tetramer reduces PYR to LACT IEA Canis familiaris 15361 R-CFA-8876312 https://reactome.org/PathwayBrowser/#/R-CFA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Canis familiaris 15361 R-CFA-893593 https://reactome.org/PathwayBrowser/#/R-CFA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Canis familiaris 15361 R-CFA-893596 https://reactome.org/PathwayBrowser/#/R-CFA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Canis familiaris 15361 R-CFA-893616 https://reactome.org/PathwayBrowser/#/R-CFA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Canis familiaris 15361 R-CFA-9012016 https://reactome.org/PathwayBrowser/#/R-CFA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Canis familiaris 15361 R-CFA-9012036 https://reactome.org/PathwayBrowser/#/R-CFA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Canis familiaris 15361 R-CFA-9012268 https://reactome.org/PathwayBrowser/#/R-CFA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Canis familiaris 15361 R-CFA-9012349 https://reactome.org/PathwayBrowser/#/R-CFA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Canis familiaris 15361 R-CFA-9012374 https://reactome.org/PathwayBrowser/#/R-CFA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Canis familiaris 15361 R-CFA-9012721 https://reactome.org/PathwayBrowser/#/R-CFA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Canis familiaris 15361 R-CFA-9013471 https://reactome.org/PathwayBrowser/#/R-CFA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Canis familiaris 15361 R-CFA-9013533 https://reactome.org/PathwayBrowser/#/R-CFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Canis familiaris 15361 R-CFA-9014741 https://reactome.org/PathwayBrowser/#/R-CFA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Canis familiaris 15361 R-CFA-9034539 https://reactome.org/PathwayBrowser/#/R-CFA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Canis familiaris 15361 R-CFA-9034756 https://reactome.org/PathwayBrowser/#/R-CFA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Canis familiaris 15361 R-CFA-904864 https://reactome.org/PathwayBrowser/#/R-CFA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Canis familiaris 15361 R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15361 R-CFA-9861660 https://reactome.org/PathwayBrowser/#/R-CFA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Canis familiaris 15361 R-CFA-9861734 https://reactome.org/PathwayBrowser/#/R-CFA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Canis familiaris 15361 R-DDI-389684 https://reactome.org/PathwayBrowser/#/R-DDI-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Dictyostelium discoideum 15361 R-DDI-507749 https://reactome.org/PathwayBrowser/#/R-DDI-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Dictyostelium discoideum 15361 R-DDI-507775 https://reactome.org/PathwayBrowser/#/R-DDI-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Dictyostelium discoideum 15361 R-DDI-70523 https://reactome.org/PathwayBrowser/#/R-DDI-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Dictyostelium discoideum 15361 R-DDI-70524 https://reactome.org/PathwayBrowser/#/R-DDI-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Dictyostelium discoideum 15361 R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 15361 R-DDI-893593 https://reactome.org/PathwayBrowser/#/R-DDI-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Dictyostelium discoideum 15361 R-DDI-893596 https://reactome.org/PathwayBrowser/#/R-DDI-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Dictyostelium discoideum 15361 R-DDI-893616 https://reactome.org/PathwayBrowser/#/R-DDI-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Dictyostelium discoideum 15361 R-DDI-9012016 https://reactome.org/PathwayBrowser/#/R-DDI-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Dictyostelium discoideum 15361 R-DDI-9012374 https://reactome.org/PathwayBrowser/#/R-DDI-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Dictyostelium discoideum 15361 R-DDI-9012721 https://reactome.org/PathwayBrowser/#/R-DDI-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Dictyostelium discoideum 15361 R-DDI-9013471 https://reactome.org/PathwayBrowser/#/R-DDI-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Dictyostelium discoideum 15361 R-DDI-9013533 https://reactome.org/PathwayBrowser/#/R-DDI-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Dictyostelium discoideum 15361 R-DDI-9014741 https://reactome.org/PathwayBrowser/#/R-DDI-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Dictyostelium discoideum 15361 R-DDI-9034539 https://reactome.org/PathwayBrowser/#/R-DDI-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Dictyostelium discoideum 15361 R-DDI-9034756 https://reactome.org/PathwayBrowser/#/R-DDI-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Dictyostelium discoideum 15361 R-DDI-9861734 https://reactome.org/PathwayBrowser/#/R-DDI-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Dictyostelium discoideum 15361 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 15361 R-DME-389684 https://reactome.org/PathwayBrowser/#/R-DME-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Drosophila melanogaster 15361 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-DME-507749 https://reactome.org/PathwayBrowser/#/R-DME-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Drosophila melanogaster 15361 R-DME-507775 https://reactome.org/PathwayBrowser/#/R-DME-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Drosophila melanogaster 15361 R-DME-6807826 https://reactome.org/PathwayBrowser/#/R-DME-6807826 LDHAL6B reduces PYR to LACT IEA Drosophila melanogaster 15361 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 15361 R-DME-70510 https://reactome.org/PathwayBrowser/#/R-DME-70510 LDH tetramer oxidises LACT to PYR IEA Drosophila melanogaster 15361 R-DME-70523 https://reactome.org/PathwayBrowser/#/R-DME-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Drosophila melanogaster 15361 R-DME-70524 https://reactome.org/PathwayBrowser/#/R-DME-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Drosophila melanogaster 15361 R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 15361 R-DME-71849 https://reactome.org/PathwayBrowser/#/R-DME-71849 LDH tetramer reduces PYR to LACT IEA Drosophila melanogaster 15361 R-DME-8876312 https://reactome.org/PathwayBrowser/#/R-DME-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-DME-893593 https://reactome.org/PathwayBrowser/#/R-DME-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Drosophila melanogaster 15361 R-DME-893596 https://reactome.org/PathwayBrowser/#/R-DME-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Drosophila melanogaster 15361 R-DME-893616 https://reactome.org/PathwayBrowser/#/R-DME-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Drosophila melanogaster 15361 R-DME-9012016 https://reactome.org/PathwayBrowser/#/R-DME-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Drosophila melanogaster 15361 R-DME-9012036 https://reactome.org/PathwayBrowser/#/R-DME-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 15361 R-DME-9012268 https://reactome.org/PathwayBrowser/#/R-DME-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 15361 R-DME-9012349 https://reactome.org/PathwayBrowser/#/R-DME-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 15361 R-DME-9012374 https://reactome.org/PathwayBrowser/#/R-DME-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Drosophila melanogaster 15361 R-DME-904864 https://reactome.org/PathwayBrowser/#/R-DME-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Drosophila melanogaster 15361 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-DME-9861660 https://reactome.org/PathwayBrowser/#/R-DME-9861660 ME1 tetramer decarboxylates OA to PYR IEA Drosophila melanogaster 15361 R-DME-9861734 https://reactome.org/PathwayBrowser/#/R-DME-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Drosophila melanogaster 15361 R-DRE-389684 https://reactome.org/PathwayBrowser/#/R-DRE-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Danio rerio 15361 R-DRE-4085217 https://reactome.org/PathwayBrowser/#/R-DRE-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Danio rerio 15361 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Danio rerio 15361 R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 15361 R-DRE-6784423 https://reactome.org/PathwayBrowser/#/R-DRE-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Danio rerio 15361 R-DRE-6807826 https://reactome.org/PathwayBrowser/#/R-DRE-6807826 LDHAL6B reduces PYR to LACT IEA Danio rerio 15361 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 15361 R-DRE-70510 https://reactome.org/PathwayBrowser/#/R-DRE-70510 LDH tetramer oxidises LACT to PYR IEA Danio rerio 15361 R-DRE-70523 https://reactome.org/PathwayBrowser/#/R-DRE-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Danio rerio 15361 R-DRE-70524 https://reactome.org/PathwayBrowser/#/R-DRE-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Danio rerio 15361 R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 15361 R-DRE-71849 https://reactome.org/PathwayBrowser/#/R-DRE-71849 LDH tetramer reduces PYR to LACT IEA Danio rerio 15361 R-DRE-8876312 https://reactome.org/PathwayBrowser/#/R-DRE-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Danio rerio 15361 R-DRE-893593 https://reactome.org/PathwayBrowser/#/R-DRE-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Danio rerio 15361 R-DRE-893596 https://reactome.org/PathwayBrowser/#/R-DRE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Danio rerio 15361 R-DRE-893616 https://reactome.org/PathwayBrowser/#/R-DRE-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Danio rerio 15361 R-DRE-9012016 https://reactome.org/PathwayBrowser/#/R-DRE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Danio rerio 15361 R-DRE-9012036 https://reactome.org/PathwayBrowser/#/R-DRE-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Danio rerio 15361 R-DRE-9012268 https://reactome.org/PathwayBrowser/#/R-DRE-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Danio rerio 15361 R-DRE-9012349 https://reactome.org/PathwayBrowser/#/R-DRE-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Danio rerio 15361 R-DRE-9012374 https://reactome.org/PathwayBrowser/#/R-DRE-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Danio rerio 15361 R-DRE-9012721 https://reactome.org/PathwayBrowser/#/R-DRE-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Danio rerio 15361 R-DRE-9013471 https://reactome.org/PathwayBrowser/#/R-DRE-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Danio rerio 15361 R-DRE-9013533 https://reactome.org/PathwayBrowser/#/R-DRE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Danio rerio 15361 R-DRE-9034756 https://reactome.org/PathwayBrowser/#/R-DRE-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Danio rerio 15361 R-DRE-904864 https://reactome.org/PathwayBrowser/#/R-DRE-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Danio rerio 15361 R-DRE-9861660 https://reactome.org/PathwayBrowser/#/R-DRE-9861660 ME1 tetramer decarboxylates OA to PYR IEA Danio rerio 15361 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 15361 R-GGA-353056 https://reactome.org/PathwayBrowser/#/R-GGA-353056 phosphoenolpyruvate + ADP => pyruvate + ATP TAS Gallus gallus 15361 R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 15361 R-GGA-372359 https://reactome.org/PathwayBrowser/#/R-GGA-372359 pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] IEA Gallus gallus 15361 R-GGA-372903 https://reactome.org/PathwayBrowser/#/R-GGA-372903 lactate + NAD+ <=> pyruvate + NADH + H+ TAS Gallus gallus 15361 R-GGA-372910 https://reactome.org/PathwayBrowser/#/R-GGA-372910 pyruvate + NADH + H+ <=> lactate + NAD+ TAS Gallus gallus 15361 R-GGA-373177 https://reactome.org/PathwayBrowser/#/R-GGA-373177 pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ TAS Gallus gallus 15361 R-GGA-389684 https://reactome.org/PathwayBrowser/#/R-GGA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Gallus gallus 15361 R-GGA-4085217 https://reactome.org/PathwayBrowser/#/R-GGA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Gallus gallus 15361 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Gallus gallus 15361 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15361 R-GGA-507749 https://reactome.org/PathwayBrowser/#/R-GGA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Gallus gallus 15361 R-GGA-507775 https://reactome.org/PathwayBrowser/#/R-GGA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Gallus gallus 15361 R-GGA-6784423 https://reactome.org/PathwayBrowser/#/R-GGA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Gallus gallus 15361 R-GGA-6807826 https://reactome.org/PathwayBrowser/#/R-GGA-6807826 LDHAL6B reduces PYR to LACT IEA Gallus gallus 15361 R-GGA-70510 https://reactome.org/PathwayBrowser/#/R-GGA-70510 LDH tetramer oxidises LACT to PYR IEA Gallus gallus 15361 R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 15361 R-GGA-71849 https://reactome.org/PathwayBrowser/#/R-GGA-71849 LDH tetramer reduces PYR to LACT IEA Gallus gallus 15361 R-GGA-8876312 https://reactome.org/PathwayBrowser/#/R-GGA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Gallus gallus 15361 R-GGA-893593 https://reactome.org/PathwayBrowser/#/R-GGA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Gallus gallus 15361 R-GGA-893596 https://reactome.org/PathwayBrowser/#/R-GGA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Gallus gallus 15361 R-GGA-893616 https://reactome.org/PathwayBrowser/#/R-GGA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Gallus gallus 15361 R-GGA-9012016 https://reactome.org/PathwayBrowser/#/R-GGA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Gallus gallus 15361 R-GGA-9012036 https://reactome.org/PathwayBrowser/#/R-GGA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Gallus gallus 15361 R-GGA-9012349 https://reactome.org/PathwayBrowser/#/R-GGA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Gallus gallus 15361 R-GGA-9012374 https://reactome.org/PathwayBrowser/#/R-GGA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Gallus gallus 15361 R-GGA-9012721 https://reactome.org/PathwayBrowser/#/R-GGA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Gallus gallus 15361 R-GGA-9013471 https://reactome.org/PathwayBrowser/#/R-GGA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Gallus gallus 15361 R-GGA-9013533 https://reactome.org/PathwayBrowser/#/R-GGA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Gallus gallus 15361 R-GGA-9014741 https://reactome.org/PathwayBrowser/#/R-GGA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Gallus gallus 15361 R-GGA-9034539 https://reactome.org/PathwayBrowser/#/R-GGA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Gallus gallus 15361 R-GGA-9034756 https://reactome.org/PathwayBrowser/#/R-GGA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Gallus gallus 15361 R-GGA-904864 https://reactome.org/PathwayBrowser/#/R-GGA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Gallus gallus 15361 R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15361 R-GGA-9861660 https://reactome.org/PathwayBrowser/#/R-GGA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Gallus gallus 15361 R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus 15361 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 15361 R-HSA-2408539 https://reactome.org/PathwayBrowser/#/R-HSA-2408539 MeSec is hydrolysed to MeSeH by PXLP-K212-CTH IEA Homo sapiens 15361 R-HSA-372342 https://reactome.org/PathwayBrowser/#/R-HSA-372342 MPC1:MPC2 imports PYR, H+ to mitochondrial matrix IEA Homo sapiens 15361 R-HSA-389684 https://reactome.org/PathwayBrowser/#/R-HSA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] TAS Homo sapiens 15361 R-HSA-4085217 https://reactome.org/PathwayBrowser/#/R-HSA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate TAS Homo sapiens 15361 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol TAS Homo sapiens 15361 R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15361 R-HSA-507749 https://reactome.org/PathwayBrowser/#/R-HSA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala TAS Homo sapiens 15361 R-HSA-507775 https://reactome.org/PathwayBrowser/#/R-HSA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR TAS Homo sapiens 15361 R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15361 R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 15361 R-HSA-6784423 https://reactome.org/PathwayBrowser/#/R-HSA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate TAS Homo sapiens 15361 R-HSA-6807826 https://reactome.org/PathwayBrowser/#/R-HSA-6807826 LDHAL6B reduces PYR to LACT TAS Homo sapiens 15361 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 15361 R-HSA-70510 https://reactome.org/PathwayBrowser/#/R-HSA-70510 LDH tetramer oxidises LACT to PYR TAS Homo sapiens 15361 R-HSA-70523 https://reactome.org/PathwayBrowser/#/R-HSA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR TAS Homo sapiens 15361 R-HSA-70524 https://reactome.org/PathwayBrowser/#/R-HSA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala TAS Homo sapiens 15361 R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 15361 R-HSA-71849 https://reactome.org/PathwayBrowser/#/R-HSA-71849 LDH tetramer reduces PYR to LACT TAS Homo sapiens 15361 R-HSA-8876312 https://reactome.org/PathwayBrowser/#/R-HSA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol TAS Homo sapiens 15361 R-HSA-893593 https://reactome.org/PathwayBrowser/#/R-HSA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine TAS Homo sapiens 15361 R-HSA-893596 https://reactome.org/PathwayBrowser/#/R-HSA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu TAS Homo sapiens 15361 R-HSA-893616 https://reactome.org/PathwayBrowser/#/R-HSA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine TAS Homo sapiens 15361 R-HSA-901097 https://reactome.org/PathwayBrowser/#/R-HSA-901097 kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2] IEA Homo sapiens 15361 R-HSA-9012016 https://reactome.org/PathwayBrowser/#/R-HSA-9012016 FAHD1 dimer hydrolyses OA to PYR TAS Homo sapiens 15361 R-HSA-9012036 https://reactome.org/PathwayBrowser/#/R-HSA-9012036 ME1 tetramer decarboxylates MAL to PYR TAS Homo sapiens 15361 R-HSA-9012268 https://reactome.org/PathwayBrowser/#/R-HSA-9012268 ME2 tetramer decarboxylates MAL to PYR TAS Homo sapiens 15361 R-HSA-9012349 https://reactome.org/PathwayBrowser/#/R-HSA-9012349 ME3 tetramer decarboxylates MAL to PYR TAS Homo sapiens 15361 R-HSA-9012374 https://reactome.org/PathwayBrowser/#/R-HSA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space TAS Homo sapiens 15361 R-HSA-9012721 https://reactome.org/PathwayBrowser/#/R-HSA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR TAS Homo sapiens 15361 R-HSA-9013471 https://reactome.org/PathwayBrowser/#/R-HSA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN TAS Homo sapiens 15361 R-HSA-9013533 https://reactome.org/PathwayBrowser/#/R-HSA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN TAS Homo sapiens 15361 R-HSA-9014741 https://reactome.org/PathwayBrowser/#/R-HSA-9014741 PXLP-K56-SRR dimer deaminates D-Ser TAS Homo sapiens 15361 R-HSA-9034539 https://reactome.org/PathwayBrowser/#/R-HSA-9034539 PXLP-K56-SRR dimer deaminates L-Ser TAS Homo sapiens 15361 R-HSA-9034756 https://reactome.org/PathwayBrowser/#/R-HSA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST TAS Homo sapiens 15361 R-HSA-904864 https://reactome.org/PathwayBrowser/#/R-HSA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate TAS Homo sapiens 15361 R-HSA-909776 https://reactome.org/PathwayBrowser/#/R-HSA-909776 beta-alanine + pyruvate => 3-oxopropanoate + alanine IEA Homo sapiens 15361 R-HSA-909780 https://reactome.org/PathwayBrowser/#/R-HSA-909780 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine IEA Homo sapiens 15361 R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15361 R-HSA-9861595 https://reactome.org/PathwayBrowser/#/R-HSA-9861595 Cytosolic H2O2 decarboxylates PYR to acetate TAS Homo sapiens 15361 R-HSA-9861660 https://reactome.org/PathwayBrowser/#/R-HSA-9861660 ME1 tetramer decarboxylates OA to PYR TAS Homo sapiens 15361 R-HSA-9861734 https://reactome.org/PathwayBrowser/#/R-HSA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT TAS Homo sapiens 15361 R-HSA-9861745 https://reactome.org/PathwayBrowser/#/R-HSA-9861745 Mitochondrial H2O2 decarboxylates PYR to acetate TAS Homo sapiens 15361 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 15361 R-MMU-389684 https://reactome.org/PathwayBrowser/#/R-MMU-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Mus musculus 15361 R-MMU-4085217 https://reactome.org/PathwayBrowser/#/R-MMU-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Mus musculus 15361 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Mus musculus 15361 R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15361 R-MMU-507749 https://reactome.org/PathwayBrowser/#/R-MMU-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Mus musculus 15361 R-MMU-507775 https://reactome.org/PathwayBrowser/#/R-MMU-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Mus musculus 15361 R-MMU-6784423 https://reactome.org/PathwayBrowser/#/R-MMU-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Mus musculus 15361 R-MMU-6807826 https://reactome.org/PathwayBrowser/#/R-MMU-6807826 LDHAL6B reduces PYR to LACT IEA Mus musculus 15361 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 15361 R-MMU-70510 https://reactome.org/PathwayBrowser/#/R-MMU-70510 LDH tetramer oxidises LACT to PYR IEA Mus musculus 15361 R-MMU-70523 https://reactome.org/PathwayBrowser/#/R-MMU-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Mus musculus 15361 R-MMU-70524 https://reactome.org/PathwayBrowser/#/R-MMU-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Mus musculus 15361 R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 15361 R-MMU-71849 https://reactome.org/PathwayBrowser/#/R-MMU-71849 LDH tetramer reduces PYR to LACT IEA Mus musculus 15361 R-MMU-8876312 https://reactome.org/PathwayBrowser/#/R-MMU-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Mus musculus 15361 R-MMU-893593 https://reactome.org/PathwayBrowser/#/R-MMU-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Mus musculus 15361 R-MMU-893596 https://reactome.org/PathwayBrowser/#/R-MMU-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Mus musculus 15361 R-MMU-893616 https://reactome.org/PathwayBrowser/#/R-MMU-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Mus musculus 15361 R-MMU-9012016 https://reactome.org/PathwayBrowser/#/R-MMU-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Mus musculus 15361 R-MMU-9012036 https://reactome.org/PathwayBrowser/#/R-MMU-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Mus musculus 15361 R-MMU-9012268 https://reactome.org/PathwayBrowser/#/R-MMU-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Mus musculus 15361 R-MMU-9012349 https://reactome.org/PathwayBrowser/#/R-MMU-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Mus musculus 15361 R-MMU-9012374 https://reactome.org/PathwayBrowser/#/R-MMU-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Mus musculus 15361 R-MMU-9012721 https://reactome.org/PathwayBrowser/#/R-MMU-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Mus musculus 15361 R-MMU-9013471 https://reactome.org/PathwayBrowser/#/R-MMU-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Mus musculus 15361 R-MMU-9013533 https://reactome.org/PathwayBrowser/#/R-MMU-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Mus musculus 15361 R-MMU-9014741 https://reactome.org/PathwayBrowser/#/R-MMU-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Mus musculus 15361 R-MMU-9034539 https://reactome.org/PathwayBrowser/#/R-MMU-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Mus musculus 15361 R-MMU-9034756 https://reactome.org/PathwayBrowser/#/R-MMU-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Mus musculus 15361 R-MMU-904864 https://reactome.org/PathwayBrowser/#/R-MMU-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Mus musculus 15361 R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15361 R-MMU-9861660 https://reactome.org/PathwayBrowser/#/R-MMU-9861660 ME1 tetramer decarboxylates OA to PYR IEA Mus musculus 15361 R-MMU-9861734 https://reactome.org/PathwayBrowser/#/R-MMU-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Mus musculus 15361 R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 15361 R-PFA-9012374 https://reactome.org/PathwayBrowser/#/R-PFA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Plasmodium falciparum 15361 R-PFA-9012721 https://reactome.org/PathwayBrowser/#/R-PFA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Plasmodium falciparum 15361 R-PFA-9013471 https://reactome.org/PathwayBrowser/#/R-PFA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Plasmodium falciparum 15361 R-PFA-9013533 https://reactome.org/PathwayBrowser/#/R-PFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Plasmodium falciparum 15361 R-PFA-9034756 https://reactome.org/PathwayBrowser/#/R-PFA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Plasmodium falciparum 15361 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 15361 R-RNO-2408538 https://reactome.org/PathwayBrowser/#/R-RNO-2408538 MeSec is hydrolysed to MeSeH by PXLP-K211-Cth TAS Rattus norvegicus 15361 R-RNO-372347 https://reactome.org/PathwayBrowser/#/R-RNO-372347 Cytosolic PYR is transported to the mitochondrial matrix TAS Rattus norvegicus 15361 R-RNO-389684 https://reactome.org/PathwayBrowser/#/R-RNO-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Rattus norvegicus 15361 R-RNO-4085217 https://reactome.org/PathwayBrowser/#/R-RNO-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Rattus norvegicus 15361 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Rattus norvegicus 15361 R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15361 R-RNO-507749 https://reactome.org/PathwayBrowser/#/R-RNO-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Rattus norvegicus 15361 R-RNO-507775 https://reactome.org/PathwayBrowser/#/R-RNO-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Rattus norvegicus 15361 R-RNO-6784423 https://reactome.org/PathwayBrowser/#/R-RNO-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Rattus norvegicus 15361 R-RNO-6807826 https://reactome.org/PathwayBrowser/#/R-RNO-6807826 LDHAL6B reduces PYR to LACT IEA Rattus norvegicus 15361 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 15361 R-RNO-70510 https://reactome.org/PathwayBrowser/#/R-RNO-70510 LDH tetramer oxidises LACT to PYR IEA Rattus norvegicus 15361 R-RNO-70523 https://reactome.org/PathwayBrowser/#/R-RNO-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Rattus norvegicus 15361 R-RNO-70524 https://reactome.org/PathwayBrowser/#/R-RNO-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Rattus norvegicus 15361 R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 15361 R-RNO-71849 https://reactome.org/PathwayBrowser/#/R-RNO-71849 LDH tetramer reduces PYR to LACT IEA Rattus norvegicus 15361 R-RNO-8876312 https://reactome.org/PathwayBrowser/#/R-RNO-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Rattus norvegicus 15361 R-RNO-893593 https://reactome.org/PathwayBrowser/#/R-RNO-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Rattus norvegicus 15361 R-RNO-893596 https://reactome.org/PathwayBrowser/#/R-RNO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Rattus norvegicus 15361 R-RNO-893616 https://reactome.org/PathwayBrowser/#/R-RNO-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Rattus norvegicus 15361 R-RNO-9012016 https://reactome.org/PathwayBrowser/#/R-RNO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Rattus norvegicus 15361 R-RNO-9012036 https://reactome.org/PathwayBrowser/#/R-RNO-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 15361 R-RNO-9012268 https://reactome.org/PathwayBrowser/#/R-RNO-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 15361 R-RNO-9012349 https://reactome.org/PathwayBrowser/#/R-RNO-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 15361 R-RNO-9012374 https://reactome.org/PathwayBrowser/#/R-RNO-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Rattus norvegicus 15361 R-RNO-9012721 https://reactome.org/PathwayBrowser/#/R-RNO-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Rattus norvegicus 15361 R-RNO-9013471 https://reactome.org/PathwayBrowser/#/R-RNO-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Rattus norvegicus 15361 R-RNO-9013533 https://reactome.org/PathwayBrowser/#/R-RNO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Rattus norvegicus 15361 R-RNO-9014741 https://reactome.org/PathwayBrowser/#/R-RNO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Rattus norvegicus 15361 R-RNO-9034539 https://reactome.org/PathwayBrowser/#/R-RNO-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Rattus norvegicus 15361 R-RNO-9034756 https://reactome.org/PathwayBrowser/#/R-RNO-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Rattus norvegicus 15361 R-RNO-904864 https://reactome.org/PathwayBrowser/#/R-RNO-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Rattus norvegicus 15361 R-RNO-909762 https://reactome.org/PathwayBrowser/#/R-RNO-909762 beta-alanine + pyruvate => 3-oxopropanoate + alanine TAS Rattus norvegicus 15361 R-RNO-909775 https://reactome.org/PathwayBrowser/#/R-RNO-909775 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine TAS Rattus norvegicus 15361 R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15361 R-RNO-9861660 https://reactome.org/PathwayBrowser/#/R-RNO-9861660 ME1 tetramer decarboxylates OA to PYR IEA Rattus norvegicus 15361 R-RNO-9861734 https://reactome.org/PathwayBrowser/#/R-RNO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Rattus norvegicus 15361 R-SCE-507749 https://reactome.org/PathwayBrowser/#/R-SCE-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Saccharomyces cerevisiae 15361 R-SCE-507775 https://reactome.org/PathwayBrowser/#/R-SCE-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Saccharomyces cerevisiae 15361 R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 15361 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 15361 R-SCE-70523 https://reactome.org/PathwayBrowser/#/R-SCE-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Saccharomyces cerevisiae 15361 R-SCE-70524 https://reactome.org/PathwayBrowser/#/R-SCE-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Saccharomyces cerevisiae 15361 R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 15361 R-SCE-893593 https://reactome.org/PathwayBrowser/#/R-SCE-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Saccharomyces cerevisiae 15361 R-SCE-893596 https://reactome.org/PathwayBrowser/#/R-SCE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Saccharomyces cerevisiae 15361 R-SCE-893616 https://reactome.org/PathwayBrowser/#/R-SCE-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Saccharomyces cerevisiae 15361 R-SCE-9012016 https://reactome.org/PathwayBrowser/#/R-SCE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Saccharomyces cerevisiae 15361 R-SCE-9012374 https://reactome.org/PathwayBrowser/#/R-SCE-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Saccharomyces cerevisiae 15361 R-SCE-9012721 https://reactome.org/PathwayBrowser/#/R-SCE-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Saccharomyces cerevisiae 15361 R-SCE-9013471 https://reactome.org/PathwayBrowser/#/R-SCE-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Saccharomyces cerevisiae 15361 R-SCE-9013533 https://reactome.org/PathwayBrowser/#/R-SCE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Saccharomyces cerevisiae 15361 R-SCE-9014741 https://reactome.org/PathwayBrowser/#/R-SCE-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Saccharomyces cerevisiae 15361 R-SCE-9034539 https://reactome.org/PathwayBrowser/#/R-SCE-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Saccharomyces cerevisiae 15361 R-SCE-9034756 https://reactome.org/PathwayBrowser/#/R-SCE-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Saccharomyces cerevisiae 15361 R-SCE-9861734 https://reactome.org/PathwayBrowser/#/R-SCE-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Saccharomyces cerevisiae 15361 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 15361 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 15361 R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 15361 R-SPO-893593 https://reactome.org/PathwayBrowser/#/R-SPO-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Schizosaccharomyces pombe 15361 R-SPO-893596 https://reactome.org/PathwayBrowser/#/R-SPO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Schizosaccharomyces pombe 15361 R-SPO-893616 https://reactome.org/PathwayBrowser/#/R-SPO-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Schizosaccharomyces pombe 15361 R-SPO-9012016 https://reactome.org/PathwayBrowser/#/R-SPO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Schizosaccharomyces pombe 15361 R-SPO-9012374 https://reactome.org/PathwayBrowser/#/R-SPO-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Schizosaccharomyces pombe 15361 R-SPO-9012721 https://reactome.org/PathwayBrowser/#/R-SPO-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Schizosaccharomyces pombe 15361 R-SPO-9013471 https://reactome.org/PathwayBrowser/#/R-SPO-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Schizosaccharomyces pombe 15361 R-SPO-9013533 https://reactome.org/PathwayBrowser/#/R-SPO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Schizosaccharomyces pombe 15361 R-SPO-9014741 https://reactome.org/PathwayBrowser/#/R-SPO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Schizosaccharomyces pombe 15361 R-SPO-9034539 https://reactome.org/PathwayBrowser/#/R-SPO-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Schizosaccharomyces pombe 15361 R-SPO-9034756 https://reactome.org/PathwayBrowser/#/R-SPO-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Schizosaccharomyces pombe 15361 R-SPO-904864 https://reactome.org/PathwayBrowser/#/R-SPO-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Schizosaccharomyces pombe 15361 R-SPO-9861734 https://reactome.org/PathwayBrowser/#/R-SPO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Schizosaccharomyces pombe 15361 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 15361 R-SSC-389684 https://reactome.org/PathwayBrowser/#/R-SSC-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Sus scrofa 15361 R-SSC-4085217 https://reactome.org/PathwayBrowser/#/R-SSC-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Sus scrofa 15361 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Sus scrofa 15361 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15361 R-SSC-507749 https://reactome.org/PathwayBrowser/#/R-SSC-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Sus scrofa 15361 R-SSC-507775 https://reactome.org/PathwayBrowser/#/R-SSC-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Sus scrofa 15361 R-SSC-6784423 https://reactome.org/PathwayBrowser/#/R-SSC-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Sus scrofa 15361 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 15361 R-SSC-70510 https://reactome.org/PathwayBrowser/#/R-SSC-70510 LDH tetramer oxidises LACT to PYR IEA Sus scrofa 15361 R-SSC-70523 https://reactome.org/PathwayBrowser/#/R-SSC-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Sus scrofa 15361 R-SSC-70524 https://reactome.org/PathwayBrowser/#/R-SSC-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Sus scrofa 15361 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 15361 R-SSC-71849 https://reactome.org/PathwayBrowser/#/R-SSC-71849 LDH tetramer reduces PYR to LACT IEA Sus scrofa 15361 R-SSC-8876312 https://reactome.org/PathwayBrowser/#/R-SSC-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Sus scrofa 15361 R-SSC-893593 https://reactome.org/PathwayBrowser/#/R-SSC-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Sus scrofa 15361 R-SSC-893596 https://reactome.org/PathwayBrowser/#/R-SSC-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Sus scrofa 15361 R-SSC-893616 https://reactome.org/PathwayBrowser/#/R-SSC-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Sus scrofa 15361 R-SSC-9012016 https://reactome.org/PathwayBrowser/#/R-SSC-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Sus scrofa 15361 R-SSC-9012036 https://reactome.org/PathwayBrowser/#/R-SSC-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Sus scrofa 15361 R-SSC-9012268 https://reactome.org/PathwayBrowser/#/R-SSC-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Sus scrofa 15361 R-SSC-9012349 https://reactome.org/PathwayBrowser/#/R-SSC-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Sus scrofa 15361 R-SSC-9012374 https://reactome.org/PathwayBrowser/#/R-SSC-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Sus scrofa 15361 R-SSC-9012721 https://reactome.org/PathwayBrowser/#/R-SSC-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Sus scrofa 15361 R-SSC-9013471 https://reactome.org/PathwayBrowser/#/R-SSC-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Sus scrofa 15361 R-SSC-9013533 https://reactome.org/PathwayBrowser/#/R-SSC-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Sus scrofa 15361 R-SSC-9014741 https://reactome.org/PathwayBrowser/#/R-SSC-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Sus scrofa 15361 R-SSC-9034539 https://reactome.org/PathwayBrowser/#/R-SSC-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Sus scrofa 15361 R-SSC-9034756 https://reactome.org/PathwayBrowser/#/R-SSC-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Sus scrofa 15361 R-SSC-904864 https://reactome.org/PathwayBrowser/#/R-SSC-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Sus scrofa 15361 R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15361 R-SSC-9861660 https://reactome.org/PathwayBrowser/#/R-SSC-9861660 ME1 tetramer decarboxylates OA to PYR IEA Sus scrofa 15361 R-SSC-9861734 https://reactome.org/PathwayBrowser/#/R-SSC-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Sus scrofa 15361 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 15361 R-XTR-389684 https://reactome.org/PathwayBrowser/#/R-XTR-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Xenopus tropicalis 15361 R-XTR-4085217 https://reactome.org/PathwayBrowser/#/R-XTR-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Xenopus tropicalis 15361 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Xenopus tropicalis 15361 R-XTR-507749 https://reactome.org/PathwayBrowser/#/R-XTR-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Xenopus tropicalis 15361 R-XTR-507775 https://reactome.org/PathwayBrowser/#/R-XTR-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Xenopus tropicalis 15361 R-XTR-6784423 https://reactome.org/PathwayBrowser/#/R-XTR-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Xenopus tropicalis 15361 R-XTR-6807826 https://reactome.org/PathwayBrowser/#/R-XTR-6807826 LDHAL6B reduces PYR to LACT IEA Xenopus tropicalis 15361 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 15361 R-XTR-70510 https://reactome.org/PathwayBrowser/#/R-XTR-70510 LDH tetramer oxidises LACT to PYR IEA Xenopus tropicalis 15361 R-XTR-70523 https://reactome.org/PathwayBrowser/#/R-XTR-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Xenopus tropicalis 15361 R-XTR-70524 https://reactome.org/PathwayBrowser/#/R-XTR-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Xenopus tropicalis 15361 R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 15361 R-XTR-71849 https://reactome.org/PathwayBrowser/#/R-XTR-71849 LDH tetramer reduces PYR to LACT IEA Xenopus tropicalis 15361 R-XTR-8876312 https://reactome.org/PathwayBrowser/#/R-XTR-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Xenopus tropicalis 15361 R-XTR-893593 https://reactome.org/PathwayBrowser/#/R-XTR-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Xenopus tropicalis 15361 R-XTR-893596 https://reactome.org/PathwayBrowser/#/R-XTR-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Xenopus tropicalis 15361 R-XTR-893616 https://reactome.org/PathwayBrowser/#/R-XTR-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Xenopus tropicalis 15361 R-XTR-9012016 https://reactome.org/PathwayBrowser/#/R-XTR-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Xenopus tropicalis 15361 R-XTR-9012268 https://reactome.org/PathwayBrowser/#/R-XTR-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 15361 R-XTR-9012349 https://reactome.org/PathwayBrowser/#/R-XTR-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 15361 R-XTR-9012374 https://reactome.org/PathwayBrowser/#/R-XTR-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Xenopus tropicalis 15361 R-XTR-9012721 https://reactome.org/PathwayBrowser/#/R-XTR-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Xenopus tropicalis 15361 R-XTR-9013471 https://reactome.org/PathwayBrowser/#/R-XTR-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Xenopus tropicalis 15361 R-XTR-9013533 https://reactome.org/PathwayBrowser/#/R-XTR-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Xenopus tropicalis 15361 R-XTR-9014741 https://reactome.org/PathwayBrowser/#/R-XTR-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Xenopus tropicalis 15361 R-XTR-9034539 https://reactome.org/PathwayBrowser/#/R-XTR-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Xenopus tropicalis 15361 R-XTR-9034756 https://reactome.org/PathwayBrowser/#/R-XTR-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Xenopus tropicalis 15361 R-XTR-904864 https://reactome.org/PathwayBrowser/#/R-XTR-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Xenopus tropicalis 15361 R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15361 R-XTR-9861734 https://reactome.org/PathwayBrowser/#/R-XTR-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Xenopus tropicalis 15365 R-BTA-9649963 https://reactome.org/PathwayBrowser/#/R-BTA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Bos taurus 15365 R-CEL-9649963 https://reactome.org/PathwayBrowser/#/R-CEL-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Caenorhabditis elegans 15365 R-CFA-9649963 https://reactome.org/PathwayBrowser/#/R-CFA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Canis familiaris 15365 R-DME-9649963 https://reactome.org/PathwayBrowser/#/R-DME-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Drosophila melanogaster 15365 R-DRE-9649963 https://reactome.org/PathwayBrowser/#/R-DRE-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Danio rerio 15365 R-GGA-9649963 https://reactome.org/PathwayBrowser/#/R-GGA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Gallus gallus 15365 R-HSA-9649963 https://reactome.org/PathwayBrowser/#/R-HSA-9649963 ASIC3 channel blockers bind ASIC3 trimer TAS Homo sapiens 15365 R-HSA-9757434 https://reactome.org/PathwayBrowser/#/R-HSA-9757434 Acetylsalicylic acid dissolves TAS Homo sapiens 15365 R-MMU-9649963 https://reactome.org/PathwayBrowser/#/R-MMU-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Mus musculus 15365 R-RNO-9649963 https://reactome.org/PathwayBrowser/#/R-RNO-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Rattus norvegicus 15365 R-SSC-9649963 https://reactome.org/PathwayBrowser/#/R-SSC-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Sus scrofa 15365 R-XTR-9649963 https://reactome.org/PathwayBrowser/#/R-XTR-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Xenopus tropicalis 15366 R-BTA-162857 https://reactome.org/PathwayBrowser/#/R-BTA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Bos taurus 15366 R-BTA-2022887 https://reactome.org/PathwayBrowser/#/R-BTA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Bos taurus 15366 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15366 R-BTA-390304 https://reactome.org/PathwayBrowser/#/R-BTA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Bos taurus 15366 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Bos taurus 15366 R-BTA-444047 https://reactome.org/PathwayBrowser/#/R-BTA-444047 Receptor FFAR3 binds carboxylates IEA Bos taurus 15366 R-BTA-444171 https://reactome.org/PathwayBrowser/#/R-BTA-444171 Receptor FFAR2 binds carboxylates IEA Bos taurus 15366 R-BTA-5433074 https://reactome.org/PathwayBrowser/#/R-BTA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Bos taurus 15366 R-BTA-5691507 https://reactome.org/PathwayBrowser/#/R-BTA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Bos taurus 15366 R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 15366 R-BTA-71735 https://reactome.org/PathwayBrowser/#/R-BTA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Bos taurus 15366 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15366 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15366 R-BTA-8869206 https://reactome.org/PathwayBrowser/#/R-BTA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Bos taurus 15366 R-BTA-9701565 https://reactome.org/PathwayBrowser/#/R-BTA-9701565 HDACs deacetylate p-STAT3 dimers IEA Bos taurus 15366 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 15366 R-CEL-162857 https://reactome.org/PathwayBrowser/#/R-CEL-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Caenorhabditis elegans 15366 R-CEL-2022887 https://reactome.org/PathwayBrowser/#/R-CEL-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Caenorhabditis elegans 15366 R-CEL-390304 https://reactome.org/PathwayBrowser/#/R-CEL-390304 acetyl-CoA + H2O => acetate + CoASH IEA Caenorhabditis elegans 15366 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Caenorhabditis elegans 15366 R-CEL-5433074 https://reactome.org/PathwayBrowser/#/R-CEL-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Caenorhabditis elegans 15366 R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 15366 R-CEL-71735 https://reactome.org/PathwayBrowser/#/R-CEL-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Caenorhabditis elegans 15366 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15366 R-CEL-8869206 https://reactome.org/PathwayBrowser/#/R-CEL-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Caenorhabditis elegans 15366 R-CEL-9701565 https://reactome.org/PathwayBrowser/#/R-CEL-9701565 HDACs deacetylate p-STAT3 dimers IEA Caenorhabditis elegans 15366 R-CFA-162857 https://reactome.org/PathwayBrowser/#/R-CFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Canis familiaris 15366 R-CFA-2022887 https://reactome.org/PathwayBrowser/#/R-CFA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Canis familiaris 15366 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15366 R-CFA-390304 https://reactome.org/PathwayBrowser/#/R-CFA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Canis familiaris 15366 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Canis familiaris 15366 R-CFA-444047 https://reactome.org/PathwayBrowser/#/R-CFA-444047 Receptor FFAR3 binds carboxylates IEA Canis familiaris 15366 R-CFA-444171 https://reactome.org/PathwayBrowser/#/R-CFA-444171 Receptor FFAR2 binds carboxylates IEA Canis familiaris 15366 R-CFA-5433074 https://reactome.org/PathwayBrowser/#/R-CFA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Canis familiaris 15366 R-CFA-5691507 https://reactome.org/PathwayBrowser/#/R-CFA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Canis familiaris 15366 R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 15366 R-CFA-71735 https://reactome.org/PathwayBrowser/#/R-CFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Canis familiaris 15366 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15366 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15366 R-CFA-8869206 https://reactome.org/PathwayBrowser/#/R-CFA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Canis familiaris 15366 R-CFA-9701565 https://reactome.org/PathwayBrowser/#/R-CFA-9701565 HDACs deacetylate p-STAT3 dimers IEA Canis familiaris 15366 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 15366 R-DDI-162857 https://reactome.org/PathwayBrowser/#/R-DDI-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Dictyostelium discoideum 15366 R-DDI-5433074 https://reactome.org/PathwayBrowser/#/R-DDI-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Dictyostelium discoideum 15366 R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 15366 R-DDI-71735 https://reactome.org/PathwayBrowser/#/R-DDI-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Dictyostelium discoideum 15366 R-DDI-9701565 https://reactome.org/PathwayBrowser/#/R-DDI-9701565 HDACs deacetylate p-STAT3 dimers IEA Dictyostelium discoideum 15366 R-DME-162857 https://reactome.org/PathwayBrowser/#/R-DME-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Drosophila melanogaster 15366 R-DME-2022887 https://reactome.org/PathwayBrowser/#/R-DME-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Drosophila melanogaster 15366 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Drosophila melanogaster 15366 R-DME-5433074 https://reactome.org/PathwayBrowser/#/R-DME-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Drosophila melanogaster 15366 R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 15366 R-DME-71735 https://reactome.org/PathwayBrowser/#/R-DME-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Drosophila melanogaster 15366 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15366 R-DME-8952069 https://reactome.org/PathwayBrowser/#/R-DME-8952069 HDAC4 deacetylates RUNX3 IEA Drosophila melanogaster 15366 R-DME-9701565 https://reactome.org/PathwayBrowser/#/R-DME-9701565 HDACs deacetylate p-STAT3 dimers IEA Drosophila melanogaster 15366 R-DRE-2022887 https://reactome.org/PathwayBrowser/#/R-DRE-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Danio rerio 15366 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 15366 R-DRE-390304 https://reactome.org/PathwayBrowser/#/R-DRE-390304 acetyl-CoA + H2O => acetate + CoASH IEA Danio rerio 15366 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Danio rerio 15366 R-DRE-444047 https://reactome.org/PathwayBrowser/#/R-DRE-444047 Receptor FFAR3 binds carboxylates IEA Danio rerio 15366 R-DRE-444171 https://reactome.org/PathwayBrowser/#/R-DRE-444171 Receptor FFAR2 binds carboxylates IEA Danio rerio 15366 R-DRE-5691507 https://reactome.org/PathwayBrowser/#/R-DRE-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Danio rerio 15366 R-DRE-9638046 https://reactome.org/PathwayBrowser/#/R-DRE-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Danio rerio 15366 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 15366 R-GGA-162857 https://reactome.org/PathwayBrowser/#/R-GGA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Gallus gallus 15366 R-GGA-2022887 https://reactome.org/PathwayBrowser/#/R-GGA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Gallus gallus 15366 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 15366 R-GGA-390304 https://reactome.org/PathwayBrowser/#/R-GGA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Gallus gallus 15366 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Gallus gallus 15366 R-GGA-444171 https://reactome.org/PathwayBrowser/#/R-GGA-444171 Receptor FFAR2 binds carboxylates IEA Gallus gallus 15366 R-GGA-5433074 https://reactome.org/PathwayBrowser/#/R-GGA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Gallus gallus 15366 R-GGA-5691507 https://reactome.org/PathwayBrowser/#/R-GGA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Gallus gallus 15366 R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 15366 R-GGA-71735 https://reactome.org/PathwayBrowser/#/R-GGA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Gallus gallus 15366 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 15366 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15366 R-GGA-8869206 https://reactome.org/PathwayBrowser/#/R-GGA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Gallus gallus 15366 R-GGA-9701565 https://reactome.org/PathwayBrowser/#/R-GGA-9701565 HDACs deacetylate p-STAT3 dimers IEA Gallus gallus 15366 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 15366 R-HSA-162857 https://reactome.org/PathwayBrowser/#/R-HSA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate TAS Homo sapiens 15366 R-HSA-2022887 https://reactome.org/PathwayBrowser/#/R-HSA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan TAS Homo sapiens 15366 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15366 R-HSA-390304 https://reactome.org/PathwayBrowser/#/R-HSA-390304 acetyl-CoA + H2O => acetate + CoASH TAS Homo sapiens 15366 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol TAS Homo sapiens 15366 R-HSA-433672 https://reactome.org/PathwayBrowser/#/R-HSA-433672 NoRC:HDAC:DNMT deacetylates histone H4 and methylates histone H3 IEA Homo sapiens 15366 R-HSA-444047 https://reactome.org/PathwayBrowser/#/R-HSA-444047 Receptor FFAR3 binds carboxylates TAS Homo sapiens 15366 R-HSA-444171 https://reactome.org/PathwayBrowser/#/R-HSA-444171 Receptor FFAR2 binds carboxylates TAS Homo sapiens 15366 R-HSA-5433074 https://reactome.org/PathwayBrowser/#/R-HSA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 15366 R-HSA-5691507 https://reactome.org/PathwayBrowser/#/R-HSA-5691507 ASPA deacetylates NAA to acetate and L-aspartate TAS Homo sapiens 15366 R-HSA-5693092 https://reactome.org/PathwayBrowser/#/R-HSA-5693092 Unknown deacetylase deacetylates 7K-BACE1(46-501) TAS Homo sapiens 15366 R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 15366 R-HSA-71735 https://reactome.org/PathwayBrowser/#/R-HSA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] TAS Homo sapiens 15366 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15366 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15366 R-HSA-8869206 https://reactome.org/PathwayBrowser/#/R-HSA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate TAS Homo sapiens 15366 R-HSA-8952069 https://reactome.org/PathwayBrowser/#/R-HSA-8952069 HDAC4 deacetylates RUNX3 TAS Homo sapiens 15366 R-HSA-9638046 https://reactome.org/PathwayBrowser/#/R-HSA-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 15366 R-HSA-9701565 https://reactome.org/PathwayBrowser/#/R-HSA-9701565 HDACs deacetylate p-STAT3 dimers TAS Homo sapiens 15366 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 15366 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 15366 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 15366 R-HSA-9737111 https://reactome.org/PathwayBrowser/#/R-HSA-9737111 Protonated weak acid translocates across the plasma membrane IEA Homo sapiens 15366 R-MMU-162857 https://reactome.org/PathwayBrowser/#/R-MMU-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Mus musculus 15366 R-MMU-2022887 https://reactome.org/PathwayBrowser/#/R-MMU-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Mus musculus 15366 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15366 R-MMU-390304 https://reactome.org/PathwayBrowser/#/R-MMU-390304 acetyl-CoA + H2O => acetate + CoASH IEA Mus musculus 15366 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Mus musculus 15366 R-MMU-444047 https://reactome.org/PathwayBrowser/#/R-MMU-444047 Receptor FFAR3 binds carboxylates IEA Mus musculus 15366 R-MMU-444171 https://reactome.org/PathwayBrowser/#/R-MMU-444171 Receptor FFAR2 binds carboxylates IEA Mus musculus 15366 R-MMU-5433074 https://reactome.org/PathwayBrowser/#/R-MMU-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 15366 R-MMU-5691507 https://reactome.org/PathwayBrowser/#/R-MMU-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Mus musculus 15366 R-MMU-573376 https://reactome.org/PathwayBrowser/#/R-MMU-573376 NoRC:intergenic spacer:Hdac:Dnmt complex deacetylates histone H4 and dimethylates lysine-9 of histone H3 in main promoter of the rRNA gene TAS Mus musculus 15366 R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 15366 R-MMU-71735 https://reactome.org/PathwayBrowser/#/R-MMU-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Mus musculus 15366 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15366 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15366 R-MMU-8869206 https://reactome.org/PathwayBrowser/#/R-MMU-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Mus musculus 15366 R-MMU-9638046 https://reactome.org/PathwayBrowser/#/R-MMU-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 15366 R-MMU-9701565 https://reactome.org/PathwayBrowser/#/R-MMU-9701565 HDACs deacetylate p-STAT3 dimers IEA Mus musculus 15366 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 15366 R-MMU-9750040 https://reactome.org/PathwayBrowser/#/R-MMU-9750040 Protonated weak acid translocates across the plasma membrane TAS Mus musculus 15366 R-MTU-879327 https://reactome.org/PathwayBrowser/#/R-MTU-879327 acetylglucosamine-inositol is deacetylated by Mca TAS Mycobacterium tuberculosis 15366 R-MTU-936642 https://reactome.org/PathwayBrowser/#/R-MTU-936642 deacetylation of O-acetylserine and sulfhydrylation using CysK1 TAS Mycobacterium tuberculosis 15366 R-MTU-936745 https://reactome.org/PathwayBrowser/#/R-MTU-936745 deacetylation of O-acetylserine and sulfhydrylation using CysK2 TAS Mycobacterium tuberculosis 15366 R-PFA-162857 https://reactome.org/PathwayBrowser/#/R-PFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Plasmodium falciparum 15366 R-PFA-71735 https://reactome.org/PathwayBrowser/#/R-PFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Plasmodium falciparum 15366 R-RNO-162857 https://reactome.org/PathwayBrowser/#/R-RNO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Rattus norvegicus 15366 R-RNO-2022887 https://reactome.org/PathwayBrowser/#/R-RNO-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Rattus norvegicus 15366 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15366 R-RNO-390304 https://reactome.org/PathwayBrowser/#/R-RNO-390304 acetyl-CoA + H2O => acetate + CoASH IEA Rattus norvegicus 15366 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Rattus norvegicus 15366 R-RNO-444047 https://reactome.org/PathwayBrowser/#/R-RNO-444047 Receptor FFAR3 binds carboxylates IEA Rattus norvegicus 15366 R-RNO-444171 https://reactome.org/PathwayBrowser/#/R-RNO-444171 Receptor FFAR2 binds carboxylates IEA Rattus norvegicus 15366 R-RNO-5433074 https://reactome.org/PathwayBrowser/#/R-RNO-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 15366 R-RNO-5691507 https://reactome.org/PathwayBrowser/#/R-RNO-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Rattus norvegicus 15366 R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 15366 R-RNO-71735 https://reactome.org/PathwayBrowser/#/R-RNO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Rattus norvegicus 15366 R-RNO-8869206 https://reactome.org/PathwayBrowser/#/R-RNO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Rattus norvegicus 15366 R-RNO-9638046 https://reactome.org/PathwayBrowser/#/R-RNO-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 15366 R-RNO-9701565 https://reactome.org/PathwayBrowser/#/R-RNO-9701565 HDACs deacetylate p-STAT3 dimers IEA Rattus norvegicus 15366 R-RNO-9749957 https://reactome.org/PathwayBrowser/#/R-RNO-9749957 Protonated weak acid translocates across the plasma membrane TAS Rattus norvegicus 15366 R-SCE-162857 https://reactome.org/PathwayBrowser/#/R-SCE-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Saccharomyces cerevisiae 15366 R-SCE-390304 https://reactome.org/PathwayBrowser/#/R-SCE-390304 acetyl-CoA + H2O => acetate + CoASH IEA Saccharomyces cerevisiae 15366 R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 15366 R-SCE-71735 https://reactome.org/PathwayBrowser/#/R-SCE-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Saccharomyces cerevisiae 15366 R-SPO-162857 https://reactome.org/PathwayBrowser/#/R-SPO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Schizosaccharomyces pombe 15366 R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 15366 R-SPO-71735 https://reactome.org/PathwayBrowser/#/R-SPO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Schizosaccharomyces pombe 15366 R-SPO-8869206 https://reactome.org/PathwayBrowser/#/R-SPO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Schizosaccharomyces pombe 15366 R-SSC-162857 https://reactome.org/PathwayBrowser/#/R-SSC-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Sus scrofa 15366 R-SSC-2022887 https://reactome.org/PathwayBrowser/#/R-SSC-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Sus scrofa 15366 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15366 R-SSC-390304 https://reactome.org/PathwayBrowser/#/R-SSC-390304 acetyl-CoA + H2O => acetate + CoASH IEA Sus scrofa 15366 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Sus scrofa 15366 R-SSC-444047 https://reactome.org/PathwayBrowser/#/R-SSC-444047 Receptor FFAR3 binds carboxylates IEA Sus scrofa 15366 R-SSC-444171 https://reactome.org/PathwayBrowser/#/R-SSC-444171 Receptor FFAR2 binds carboxylates IEA Sus scrofa 15366 R-SSC-5433074 https://reactome.org/PathwayBrowser/#/R-SSC-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Sus scrofa 15366 R-SSC-5691507 https://reactome.org/PathwayBrowser/#/R-SSC-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Sus scrofa 15366 R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 15366 R-SSC-71735 https://reactome.org/PathwayBrowser/#/R-SSC-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Sus scrofa 15366 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15366 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15366 R-SSC-8869206 https://reactome.org/PathwayBrowser/#/R-SSC-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Sus scrofa 15366 R-SSC-9701565 https://reactome.org/PathwayBrowser/#/R-SSC-9701565 HDACs deacetylate p-STAT3 dimers IEA Sus scrofa 15366 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 15366 R-XTR-162857 https://reactome.org/PathwayBrowser/#/R-XTR-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Xenopus tropicalis 15366 R-XTR-2022887 https://reactome.org/PathwayBrowser/#/R-XTR-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Xenopus tropicalis 15366 R-XTR-390304 https://reactome.org/PathwayBrowser/#/R-XTR-390304 acetyl-CoA + H2O => acetate + CoASH IEA Xenopus tropicalis 15366 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Xenopus tropicalis 15366 R-XTR-444171 https://reactome.org/PathwayBrowser/#/R-XTR-444171 Receptor FFAR2 binds carboxylates IEA Xenopus tropicalis 15366 R-XTR-5433074 https://reactome.org/PathwayBrowser/#/R-XTR-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 15366 R-XTR-5691507 https://reactome.org/PathwayBrowser/#/R-XTR-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Xenopus tropicalis 15366 R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 15366 R-XTR-71735 https://reactome.org/PathwayBrowser/#/R-XTR-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Xenopus tropicalis 15366 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 15366 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15366 R-XTR-8869206 https://reactome.org/PathwayBrowser/#/R-XTR-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Xenopus tropicalis 15366 R-XTR-9638046 https://reactome.org/PathwayBrowser/#/R-XTR-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 15366 R-XTR-9701565 https://reactome.org/PathwayBrowser/#/R-XTR-9701565 HDACs deacetylate p-STAT3 dimers IEA Xenopus tropicalis 15367 R-BTA-200406 https://reactome.org/PathwayBrowser/#/R-BTA-200406 CPT1A,B transfers PALM to CAR IEA Bos taurus 15367 R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 15367 R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 15367 R-BTA-5246478 https://reactome.org/PathwayBrowser/#/R-BTA-5246478 APOM binds retinoids IEA Bos taurus 15367 R-BTA-5334827 https://reactome.org/PathwayBrowser/#/R-BTA-5334827 SUMO-CRABP2 binds atRA IEA Bos taurus 15367 R-BTA-5334854 https://reactome.org/PathwayBrowser/#/R-BTA-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Bos taurus 15367 R-BTA-5362522 https://reactome.org/PathwayBrowser/#/R-BTA-5362522 ALDHs oxidise atRAL to atRA IEA Bos taurus 15367 R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 15367 R-BTA-5422942 https://reactome.org/PathwayBrowser/#/R-BTA-5422942 RXRA:PPARD binds FABP5:atRA IEA Bos taurus 15367 R-BTA-5622129 https://reactome.org/PathwayBrowser/#/R-BTA-5622129 FABP5 binds atRA IEA Bos taurus 15367 R-BTA-5622134 https://reactome.org/PathwayBrowser/#/R-BTA-5622134 CRABP1 binds atRA IEA Bos taurus 15367 R-BTA-5633256 https://reactome.org/PathwayBrowser/#/R-BTA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Bos taurus 15367 R-BTA-5634100 https://reactome.org/PathwayBrowser/#/R-BTA-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Bos taurus 15367 R-BTA-5634103 https://reactome.org/PathwayBrowser/#/R-BTA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Bos taurus 15367 R-BTA-5634104 https://reactome.org/PathwayBrowser/#/R-BTA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Bos taurus 15367 R-BTA-8869568 https://reactome.org/PathwayBrowser/#/R-BTA-8869568 NPM1 binds TFAP2A homodimer IEA Bos taurus 15367 R-BTA-9617067 https://reactome.org/PathwayBrowser/#/R-BTA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Bos taurus 15367 R-CEL-200406 https://reactome.org/PathwayBrowser/#/R-CEL-200406 CPT1A,B transfers PALM to CAR IEA Caenorhabditis elegans 15367 R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 15367 R-CEL-5334827 https://reactome.org/PathwayBrowser/#/R-CEL-5334827 SUMO-CRABP2 binds atRA IEA Caenorhabditis elegans 15367 R-CEL-5334854 https://reactome.org/PathwayBrowser/#/R-CEL-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Caenorhabditis elegans 15367 R-CEL-5362522 https://reactome.org/PathwayBrowser/#/R-CEL-5362522 ALDHs oxidise atRAL to atRA IEA Caenorhabditis elegans 15367 R-CEL-5422942 https://reactome.org/PathwayBrowser/#/R-CEL-5422942 RXRA:PPARD binds FABP5:atRA IEA Caenorhabditis elegans 15367 R-CEL-5622129 https://reactome.org/PathwayBrowser/#/R-CEL-5622129 FABP5 binds atRA IEA Caenorhabditis elegans 15367 R-CEL-5622134 https://reactome.org/PathwayBrowser/#/R-CEL-5622134 CRABP1 binds atRA IEA Caenorhabditis elegans 15367 R-CEL-5633256 https://reactome.org/PathwayBrowser/#/R-CEL-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Caenorhabditis elegans 15367 R-CEL-5634100 https://reactome.org/PathwayBrowser/#/R-CEL-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Caenorhabditis elegans 15367 R-CEL-5634103 https://reactome.org/PathwayBrowser/#/R-CEL-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Caenorhabditis elegans 15367 R-CEL-5634104 https://reactome.org/PathwayBrowser/#/R-CEL-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Caenorhabditis elegans 15367 R-CEL-9617067 https://reactome.org/PathwayBrowser/#/R-CEL-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Caenorhabditis elegans 15367 R-CFA-200406 https://reactome.org/PathwayBrowser/#/R-CFA-200406 CPT1A,B transfers PALM to CAR IEA Canis familiaris 15367 R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 15367 R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 15367 R-CFA-5246478 https://reactome.org/PathwayBrowser/#/R-CFA-5246478 APOM binds retinoids IEA Canis familiaris 15367 R-CFA-5334827 https://reactome.org/PathwayBrowser/#/R-CFA-5334827 SUMO-CRABP2 binds atRA IEA Canis familiaris 15367 R-CFA-5334854 https://reactome.org/PathwayBrowser/#/R-CFA-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Canis familiaris 15367 R-CFA-5362522 https://reactome.org/PathwayBrowser/#/R-CFA-5362522 ALDHs oxidise atRAL to atRA IEA Canis familiaris 15367 R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 15367 R-CFA-5422942 https://reactome.org/PathwayBrowser/#/R-CFA-5422942 RXRA:PPARD binds FABP5:atRA IEA Canis familiaris 15367 R-CFA-5622129 https://reactome.org/PathwayBrowser/#/R-CFA-5622129 FABP5 binds atRA IEA Canis familiaris 15367 R-CFA-5622134 https://reactome.org/PathwayBrowser/#/R-CFA-5622134 CRABP1 binds atRA IEA Canis familiaris 15367 R-CFA-5633256 https://reactome.org/PathwayBrowser/#/R-CFA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Canis familiaris 15367 R-CFA-5634100 https://reactome.org/PathwayBrowser/#/R-CFA-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Canis familiaris 15367 R-CFA-5634103 https://reactome.org/PathwayBrowser/#/R-CFA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Canis familiaris 15367 R-CFA-5634104 https://reactome.org/PathwayBrowser/#/R-CFA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Canis familiaris 15367 R-CFA-8869568 https://reactome.org/PathwayBrowser/#/R-CFA-8869568 NPM1 binds TFAP2A homodimer IEA Canis familiaris 15367 R-CFA-9617067 https://reactome.org/PathwayBrowser/#/R-CFA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Canis familiaris 15367 R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 15367 R-DDI-5362522 https://reactome.org/PathwayBrowser/#/R-DDI-5362522 ALDHs oxidise atRAL to atRA IEA Dictyostelium discoideum 15367 R-DME-200406 https://reactome.org/PathwayBrowser/#/R-DME-200406 CPT1A,B transfers PALM to CAR IEA Drosophila melanogaster 15367 R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 15367 R-DME-5334827 https://reactome.org/PathwayBrowser/#/R-DME-5334827 SUMO-CRABP2 binds atRA IEA Drosophila melanogaster 15367 R-DME-5334854 https://reactome.org/PathwayBrowser/#/R-DME-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Drosophila melanogaster 15367 R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster 15367 R-DME-5622134 https://reactome.org/PathwayBrowser/#/R-DME-5622134 CRABP1 binds atRA IEA Drosophila melanogaster 15367 R-DME-5634103 https://reactome.org/PathwayBrowser/#/R-DME-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Drosophila melanogaster 15367 R-DME-5634104 https://reactome.org/PathwayBrowser/#/R-DME-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Drosophila melanogaster 15367 R-DME-8869568 https://reactome.org/PathwayBrowser/#/R-DME-8869568 NPM1 binds TFAP2A homodimer IEA Drosophila melanogaster 15367 R-DME-9617067 https://reactome.org/PathwayBrowser/#/R-DME-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Drosophila melanogaster 15367 R-DRE-200406 https://reactome.org/PathwayBrowser/#/R-DRE-200406 CPT1A,B transfers PALM to CAR IEA Danio rerio 15367 R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 15367 R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 15367 R-DRE-5334827 https://reactome.org/PathwayBrowser/#/R-DRE-5334827 SUMO-CRABP2 binds atRA IEA Danio rerio 15367 R-DRE-5334854 https://reactome.org/PathwayBrowser/#/R-DRE-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Danio rerio 15367 R-DRE-5362522 https://reactome.org/PathwayBrowser/#/R-DRE-5362522 ALDHs oxidise atRAL to atRA IEA Danio rerio 15367 R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 15367 R-DRE-5622134 https://reactome.org/PathwayBrowser/#/R-DRE-5622134 CRABP1 binds atRA IEA Danio rerio 15367 R-DRE-5634103 https://reactome.org/PathwayBrowser/#/R-DRE-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Danio rerio 15367 R-DRE-5634104 https://reactome.org/PathwayBrowser/#/R-DRE-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Danio rerio 15367 R-DRE-9617067 https://reactome.org/PathwayBrowser/#/R-DRE-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Danio rerio 15367 R-GGA-200406 https://reactome.org/PathwayBrowser/#/R-GGA-200406 CPT1A,B transfers PALM to CAR IEA Gallus gallus 15367 R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 15367 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 15367 R-GGA-5334827 https://reactome.org/PathwayBrowser/#/R-GGA-5334827 SUMO-CRABP2 binds atRA IEA Gallus gallus 15367 R-GGA-5334854 https://reactome.org/PathwayBrowser/#/R-GGA-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Gallus gallus 15367 R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus 15367 R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 15367 R-GGA-5422942 https://reactome.org/PathwayBrowser/#/R-GGA-5422942 RXRA:PPARD binds FABP5:atRA IEA Gallus gallus 15367 R-GGA-5622129 https://reactome.org/PathwayBrowser/#/R-GGA-5622129 FABP5 binds atRA IEA Gallus gallus 15367 R-GGA-5622134 https://reactome.org/PathwayBrowser/#/R-GGA-5622134 CRABP1 binds atRA IEA Gallus gallus 15367 R-GGA-5633256 https://reactome.org/PathwayBrowser/#/R-GGA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Gallus gallus 15367 R-GGA-5634100 https://reactome.org/PathwayBrowser/#/R-GGA-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Gallus gallus 15367 R-GGA-5634103 https://reactome.org/PathwayBrowser/#/R-GGA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Gallus gallus 15367 R-GGA-5634104 https://reactome.org/PathwayBrowser/#/R-GGA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Gallus gallus 15367 R-GGA-8869568 https://reactome.org/PathwayBrowser/#/R-GGA-8869568 NPM1 binds TFAP2A homodimer IEA Gallus gallus 15367 R-GGA-9617067 https://reactome.org/PathwayBrowser/#/R-GGA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Gallus gallus 15367 R-HSA-200406 https://reactome.org/PathwayBrowser/#/R-HSA-200406 CPT1A,B transfers PALM to CAR TAS Homo sapiens 15367 R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 15367 R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 15367 R-HSA-5246478 https://reactome.org/PathwayBrowser/#/R-HSA-5246478 APOM binds retinoids TAS Homo sapiens 15367 R-HSA-5334827 https://reactome.org/PathwayBrowser/#/R-HSA-5334827 SUMO-CRABP2 binds atRA TAS Homo sapiens 15367 R-HSA-5334854 https://reactome.org/PathwayBrowser/#/R-HSA-5334854 RAR:RXR binds SUMO-CRABP2:atRA TAS Homo sapiens 15367 R-HSA-5362522 https://reactome.org/PathwayBrowser/#/R-HSA-5362522 ALDHs oxidise atRAL to atRA TAS Homo sapiens 15367 R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 15367 R-HSA-5422942 https://reactome.org/PathwayBrowser/#/R-HSA-5422942 RXRA:PPARD binds FABP5:atRA TAS Homo sapiens 15367 R-HSA-5602063 https://reactome.org/PathwayBrowser/#/R-HSA-5602063 Defective CYP26B1 does not 4-hydroxylate atRA TAS Homo sapiens 15367 R-HSA-5617431 https://reactome.org/PathwayBrowser/#/R-HSA-5617431 Retinoic acid activates HOXA1 chromatin IEA Homo sapiens 15367 R-HSA-5617445 https://reactome.org/PathwayBrowser/#/R-HSA-5617445 HOXD1 chromatin is activated IEA Homo sapiens 15367 R-HSA-5617452 https://reactome.org/PathwayBrowser/#/R-HSA-5617452 Retinoic acid activates HOXB1 chromatin IEA Homo sapiens 15367 R-HSA-5617454 https://reactome.org/PathwayBrowser/#/R-HSA-5617454 HOXB1 gene is transcribed IEA Homo sapiens 15367 R-HSA-5617471 https://reactome.org/PathwayBrowser/#/R-HSA-5617471 HOXA1 gene is transcribed IEA Homo sapiens 15367 R-HSA-5617650 https://reactome.org/PathwayBrowser/#/R-HSA-5617650 HOXD3 chromatin is activated IEA Homo sapiens 15367 R-HSA-5617859 https://reactome.org/PathwayBrowser/#/R-HSA-5617859 Retinoic acid activates HOXB4 chromatin IEA Homo sapiens 15367 R-HSA-5617862 https://reactome.org/PathwayBrowser/#/R-HSA-5617862 Retinoic acid activates HOXA4 chromatin IEA Homo sapiens 15367 R-HSA-5617867 https://reactome.org/PathwayBrowser/#/R-HSA-5617867 HOXB4 gene is transcribed IEA Homo sapiens 15367 R-HSA-5617874 https://reactome.org/PathwayBrowser/#/R-HSA-5617874 HOXD4 gene is transcribed IEA Homo sapiens 15367 R-HSA-5617877 https://reactome.org/PathwayBrowser/#/R-HSA-5617877 HOXA4 gene is transcribed IEA Homo sapiens 15367 R-HSA-5617896 https://reactome.org/PathwayBrowser/#/R-HSA-5617896 Retinoic acid activates HOXD4 chromatin IEA Homo sapiens 15367 R-HSA-5622129 https://reactome.org/PathwayBrowser/#/R-HSA-5622129 FABP5 binds atRA TAS Homo sapiens 15367 R-HSA-5622134 https://reactome.org/PathwayBrowser/#/R-HSA-5622134 CRABP1 binds atRA TAS Homo sapiens 15367 R-HSA-5633256 https://reactome.org/PathwayBrowser/#/R-HSA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm TAS Homo sapiens 15367 R-HSA-5634100 https://reactome.org/PathwayBrowser/#/R-HSA-5634100 FABP5 dissociates from RXRA:PPARD:atRA TAS Homo sapiens 15367 R-HSA-5634103 https://reactome.org/PathwayBrowser/#/R-HSA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR TAS Homo sapiens 15367 R-HSA-5634104 https://reactome.org/PathwayBrowser/#/R-HSA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus TAS Homo sapiens 15367 R-HSA-5693644 https://reactome.org/PathwayBrowser/#/R-HSA-5693644 HOXB1 maintains activation of HOXB1 chromatin IEA Homo sapiens 15367 R-HSA-6810139 https://reactome.org/PathwayBrowser/#/R-HSA-6810139 HOXA2 chromatin is activated IEA Homo sapiens 15367 R-HSA-6810159 https://reactome.org/PathwayBrowser/#/R-HSA-6810159 HOXB2 chromatin is activated IEA Homo sapiens 15367 R-HSA-8869568 https://reactome.org/PathwayBrowser/#/R-HSA-8869568 NPM1 binds TFAP2A homodimer TAS Homo sapiens 15367 R-HSA-9617067 https://reactome.org/PathwayBrowser/#/R-HSA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene TAS Homo sapiens 15367 R-HSA-9634433 https://reactome.org/PathwayBrowser/#/R-HSA-9634433 CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid IEA Homo sapiens 15367 R-HSA-9727359 https://reactome.org/PathwayBrowser/#/R-HSA-9727359 Keratinocyte of spinosum layer differentiates into keratinocyte of granulosum layer in interfollicular epidermis TAS Homo sapiens 15367 R-HSA-9761166 https://reactome.org/PathwayBrowser/#/R-HSA-9761166 Expression of LHX1 in intermediate mesoderm IEA Homo sapiens 15367 R-HSA-9761170 https://reactome.org/PathwayBrowser/#/R-HSA-9761170 Expression of PAX2 in intermediate mesoderm IEA Homo sapiens 15367 R-HSA-9761173 https://reactome.org/PathwayBrowser/#/R-HSA-9761173 Expression of PAX8 in intermediate mesoderm IEA Homo sapiens 15367 R-HSA-9761186 https://reactome.org/PathwayBrowser/#/R-HSA-9761186 Expression of OSR1 in intermediate mesoderm IEA Homo sapiens 15367 R-HSA-9830480 https://reactome.org/PathwayBrowser/#/R-HSA-9830480 Expression of RET in the nephric duct IEA Homo sapiens 15367 R-MMU-200406 https://reactome.org/PathwayBrowser/#/R-MMU-200406 CPT1A,B transfers PALM to CAR IEA Mus musculus 15367 R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 15367 R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 15367 R-MMU-5246478 https://reactome.org/PathwayBrowser/#/R-MMU-5246478 APOM binds retinoids IEA Mus musculus 15367 R-MMU-5334827 https://reactome.org/PathwayBrowser/#/R-MMU-5334827 SUMO-CRABP2 binds atRA IEA Mus musculus 15367 R-MMU-5334854 https://reactome.org/PathwayBrowser/#/R-MMU-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Mus musculus 15367 R-MMU-5362522 https://reactome.org/PathwayBrowser/#/R-MMU-5362522 ALDHs oxidise atRAL to atRA IEA Mus musculus 15367 R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 15367 R-MMU-5422942 https://reactome.org/PathwayBrowser/#/R-MMU-5422942 RXRA:PPARD binds FABP5:atRA IEA Mus musculus 15367 R-MMU-5617960 https://reactome.org/PathwayBrowser/#/R-MMU-5617960 Retinoic acid activates Hoxb1 chromatin TAS Mus musculus 15367 R-MMU-5617972 https://reactome.org/PathwayBrowser/#/R-MMU-5617972 Hoxb1 gene is transcribed TAS Mus musculus 15367 R-MMU-5617990 https://reactome.org/PathwayBrowser/#/R-MMU-5617990 Retinoic acid activates Hoxa1 chromatin TAS Mus musculus 15367 R-MMU-5617999 https://reactome.org/PathwayBrowser/#/R-MMU-5617999 Hoxa1 gene is transcribed TAS Mus musculus 15367 R-MMU-5619411 https://reactome.org/PathwayBrowser/#/R-MMU-5619411 Retinoic acid activates Hoxb4 chromatin TAS Mus musculus 15367 R-MMU-5619414 https://reactome.org/PathwayBrowser/#/R-MMU-5619414 Hoxa4 gene is transcribed TAS Mus musculus 15367 R-MMU-5619417 https://reactome.org/PathwayBrowser/#/R-MMU-5619417 Hoxb4 gene is transcribed TAS Mus musculus 15367 R-MMU-5619421 https://reactome.org/PathwayBrowser/#/R-MMU-5619421 Hoxd4 gene is transcribed TAS Mus musculus 15367 R-MMU-5619434 https://reactome.org/PathwayBrowser/#/R-MMU-5619434 Retinoic acid activates Hoxa4 chromatin TAS Mus musculus 15367 R-MMU-5619441 https://reactome.org/PathwayBrowser/#/R-MMU-5619441 Retinoic acid activates Hoxd4 chromatin TAS Mus musculus 15367 R-MMU-5622129 https://reactome.org/PathwayBrowser/#/R-MMU-5622129 FABP5 binds atRA IEA Mus musculus 15367 R-MMU-5622134 https://reactome.org/PathwayBrowser/#/R-MMU-5622134 CRABP1 binds atRA IEA Mus musculus 15367 R-MMU-5633256 https://reactome.org/PathwayBrowser/#/R-MMU-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Mus musculus 15367 R-MMU-5634100 https://reactome.org/PathwayBrowser/#/R-MMU-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Mus musculus 15367 R-MMU-5634103 https://reactome.org/PathwayBrowser/#/R-MMU-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Mus musculus 15367 R-MMU-5634104 https://reactome.org/PathwayBrowser/#/R-MMU-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Mus musculus 15367 R-MMU-5693628 https://reactome.org/PathwayBrowser/#/R-MMU-5693628 Hoxb1 maintains activation of Hoxb1 chromatin TAS Mus musculus 15367 R-MMU-8869568 https://reactome.org/PathwayBrowser/#/R-MMU-8869568 NPM1 binds TFAP2A homodimer IEA Mus musculus 15367 R-MMU-9617067 https://reactome.org/PathwayBrowser/#/R-MMU-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Mus musculus 15367 R-MMU-9761177 https://reactome.org/PathwayBrowser/#/R-MMU-9761177 Expression of Pax2 in intermediate mesoderm TAS Mus musculus 15367 R-MMU-9761192 https://reactome.org/PathwayBrowser/#/R-MMU-9761192 Expression of Pax8 in intermediate mesoderm TAS Mus musculus 15367 R-MMU-9766551 https://reactome.org/PathwayBrowser/#/R-MMU-9766551 Expression of Osr1 in intermediate mesoderm TAS Mus musculus 15367 R-RNO-200406 https://reactome.org/PathwayBrowser/#/R-RNO-200406 CPT1A,B transfers PALM to CAR IEA Rattus norvegicus 15367 R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 15367 R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 15367 R-RNO-5246478 https://reactome.org/PathwayBrowser/#/R-RNO-5246478 APOM binds retinoids IEA Rattus norvegicus 15367 R-RNO-5334827 https://reactome.org/PathwayBrowser/#/R-RNO-5334827 SUMO-CRABP2 binds atRA IEA Rattus norvegicus 15367 R-RNO-5334854 https://reactome.org/PathwayBrowser/#/R-RNO-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Rattus norvegicus 15367 R-RNO-5362522 https://reactome.org/PathwayBrowser/#/R-RNO-5362522 ALDHs oxidise atRAL to atRA IEA Rattus norvegicus 15367 R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 15367 R-RNO-5422942 https://reactome.org/PathwayBrowser/#/R-RNO-5422942 RXRA:PPARD binds FABP5:atRA IEA Rattus norvegicus 15367 R-RNO-5622129 https://reactome.org/PathwayBrowser/#/R-RNO-5622129 FABP5 binds atRA IEA Rattus norvegicus 15367 R-RNO-5622134 https://reactome.org/PathwayBrowser/#/R-RNO-5622134 CRABP1 binds atRA IEA Rattus norvegicus 15367 R-RNO-5633256 https://reactome.org/PathwayBrowser/#/R-RNO-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Rattus norvegicus 15367 R-RNO-5634100 https://reactome.org/PathwayBrowser/#/R-RNO-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Rattus norvegicus 15367 R-RNO-5634103 https://reactome.org/PathwayBrowser/#/R-RNO-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Rattus norvegicus 15367 R-RNO-5634104 https://reactome.org/PathwayBrowser/#/R-RNO-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Rattus norvegicus 15367 R-RNO-8869568 https://reactome.org/PathwayBrowser/#/R-RNO-8869568 NPM1 binds TFAP2A homodimer IEA Rattus norvegicus 15367 R-RNO-9617067 https://reactome.org/PathwayBrowser/#/R-RNO-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Rattus norvegicus 15367 R-SCE-5362522 https://reactome.org/PathwayBrowser/#/R-SCE-5362522 ALDHs oxidise atRAL to atRA IEA Saccharomyces cerevisiae 15367 R-SPO-5362522 https://reactome.org/PathwayBrowser/#/R-SPO-5362522 ALDHs oxidise atRAL to atRA IEA Schizosaccharomyces pombe 15367 R-SSC-200406 https://reactome.org/PathwayBrowser/#/R-SSC-200406 CPT1A,B transfers PALM to CAR IEA Sus scrofa 15367 R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 15367 R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 15367 R-SSC-5246478 https://reactome.org/PathwayBrowser/#/R-SSC-5246478 APOM binds retinoids IEA Sus scrofa 15367 R-SSC-5334827 https://reactome.org/PathwayBrowser/#/R-SSC-5334827 SUMO-CRABP2 binds atRA IEA Sus scrofa 15367 R-SSC-5334854 https://reactome.org/PathwayBrowser/#/R-SSC-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Sus scrofa 15367 R-SSC-5362522 https://reactome.org/PathwayBrowser/#/R-SSC-5362522 ALDHs oxidise atRAL to atRA IEA Sus scrofa 15367 R-SSC-5362525 https://reactome.org/PathwayBrowser/#/R-SSC-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Sus scrofa 15367 R-SSC-5422942 https://reactome.org/PathwayBrowser/#/R-SSC-5422942 RXRA:PPARD binds FABP5:atRA IEA Sus scrofa 15367 R-SSC-5622129 https://reactome.org/PathwayBrowser/#/R-SSC-5622129 FABP5 binds atRA IEA Sus scrofa 15367 R-SSC-5622134 https://reactome.org/PathwayBrowser/#/R-SSC-5622134 CRABP1 binds atRA IEA Sus scrofa 15367 R-SSC-5633256 https://reactome.org/PathwayBrowser/#/R-SSC-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Sus scrofa 15367 R-SSC-5634100 https://reactome.org/PathwayBrowser/#/R-SSC-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Sus scrofa 15367 R-SSC-5634103 https://reactome.org/PathwayBrowser/#/R-SSC-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Sus scrofa 15367 R-SSC-5634104 https://reactome.org/PathwayBrowser/#/R-SSC-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Sus scrofa 15367 R-SSC-8869568 https://reactome.org/PathwayBrowser/#/R-SSC-8869568 NPM1 binds TFAP2A homodimer IEA Sus scrofa 15367 R-SSC-9617067 https://reactome.org/PathwayBrowser/#/R-SSC-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Sus scrofa 15367 R-XTR-200406 https://reactome.org/PathwayBrowser/#/R-XTR-200406 CPT1A,B transfers PALM to CAR IEA Xenopus tropicalis 15367 R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 15367 R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 15367 R-XTR-5246478 https://reactome.org/PathwayBrowser/#/R-XTR-5246478 APOM binds retinoids IEA Xenopus tropicalis 15367 R-XTR-5334827 https://reactome.org/PathwayBrowser/#/R-XTR-5334827 SUMO-CRABP2 binds atRA IEA Xenopus tropicalis 15367 R-XTR-5362522 https://reactome.org/PathwayBrowser/#/R-XTR-5362522 ALDHs oxidise atRAL to atRA IEA Xenopus tropicalis 15367 R-XTR-5362525 https://reactome.org/PathwayBrowser/#/R-XTR-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Xenopus tropicalis 15367 R-XTR-5422942 https://reactome.org/PathwayBrowser/#/R-XTR-5422942 RXRA:PPARD binds FABP5:atRA IEA Xenopus tropicalis 15367 R-XTR-5622129 https://reactome.org/PathwayBrowser/#/R-XTR-5622129 FABP5 binds atRA IEA Xenopus tropicalis 15367 R-XTR-5622134 https://reactome.org/PathwayBrowser/#/R-XTR-5622134 CRABP1 binds atRA IEA Xenopus tropicalis 15367 R-XTR-5633256 https://reactome.org/PathwayBrowser/#/R-XTR-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Xenopus tropicalis 15367 R-XTR-5634100 https://reactome.org/PathwayBrowser/#/R-XTR-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Xenopus tropicalis 15367 R-XTR-5634104 https://reactome.org/PathwayBrowser/#/R-XTR-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Xenopus tropicalis 15367 R-XTR-8869568 https://reactome.org/PathwayBrowser/#/R-XTR-8869568 NPM1 binds TFAP2A homodimer IEA Xenopus tropicalis 15371 R-BTA-389995 https://reactome.org/PathwayBrowser/#/R-BTA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Bos taurus 15371 R-BTA-390224 https://reactome.org/PathwayBrowser/#/R-BTA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Bos taurus 15371 R-CEL-389995 https://reactome.org/PathwayBrowser/#/R-CEL-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Caenorhabditis elegans 15371 R-CFA-389995 https://reactome.org/PathwayBrowser/#/R-CFA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Canis familiaris 15371 R-CFA-390224 https://reactome.org/PathwayBrowser/#/R-CFA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Canis familiaris 15371 R-DDI-389995 https://reactome.org/PathwayBrowser/#/R-DDI-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Dictyostelium discoideum 15371 R-DME-389995 https://reactome.org/PathwayBrowser/#/R-DME-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Drosophila melanogaster 15371 R-DME-390224 https://reactome.org/PathwayBrowser/#/R-DME-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Drosophila melanogaster 15371 R-DRE-390224 https://reactome.org/PathwayBrowser/#/R-DRE-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Danio rerio 15371 R-GGA-389995 https://reactome.org/PathwayBrowser/#/R-GGA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Gallus gallus 15371 R-GGA-390224 https://reactome.org/PathwayBrowser/#/R-GGA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Gallus gallus 15371 R-HSA-389995 https://reactome.org/PathwayBrowser/#/R-HSA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ TAS Homo sapiens 15371 R-HSA-390224 https://reactome.org/PathwayBrowser/#/R-HSA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA TAS Homo sapiens 15371 R-MMU-389995 https://reactome.org/PathwayBrowser/#/R-MMU-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Mus musculus 15371 R-MMU-390224 https://reactome.org/PathwayBrowser/#/R-MMU-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Mus musculus 15371 R-RNO-389995 https://reactome.org/PathwayBrowser/#/R-RNO-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Rattus norvegicus 15371 R-RNO-390224 https://reactome.org/PathwayBrowser/#/R-RNO-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Rattus norvegicus 15372 R-BTA-1474146 https://reactome.org/PathwayBrowser/#/R-BTA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Bos taurus 15372 R-BTA-1475414 https://reactome.org/PathwayBrowser/#/R-BTA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Bos taurus 15372 R-BTA-1497784 https://reactome.org/PathwayBrowser/#/R-BTA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Bos taurus 15372 R-BTA-1497796 https://reactome.org/PathwayBrowser/#/R-BTA-1497796 BH2 binding can lead to eNOS uncoupling IEA Bos taurus 15372 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 15372 R-BTA-202111 https://reactome.org/PathwayBrowser/#/R-BTA-202111 AKT1 phosphorylates eNOS IEA Bos taurus 15372 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 15372 R-BTA-202132 https://reactome.org/PathwayBrowser/#/R-BTA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Bos taurus 15372 R-BTA-203613 https://reactome.org/PathwayBrowser/#/R-BTA-203613 depalmitoylation of eNOS IEA Bos taurus 15372 R-BTA-203625 https://reactome.org/PathwayBrowser/#/R-BTA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Bos taurus 15372 R-BTA-203680 https://reactome.org/PathwayBrowser/#/R-BTA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Bos taurus 15372 R-BTA-209823 https://reactome.org/PathwayBrowser/#/R-BTA-209823 Tyrosine is hydroxylated to dopa IEA Bos taurus 15372 R-BTA-209828 https://reactome.org/PathwayBrowser/#/R-BTA-209828 Tryptophan is hydroxylated IEA Bos taurus 15372 R-BTA-5696119 https://reactome.org/PathwayBrowser/#/R-BTA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Bos taurus 15372 R-BTA-71118 https://reactome.org/PathwayBrowser/#/R-BTA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Bos taurus 15372 R-BTA-71130 https://reactome.org/PathwayBrowser/#/R-BTA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Bos taurus 15372 R-CEL-1474146 https://reactome.org/PathwayBrowser/#/R-CEL-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Caenorhabditis elegans 15372 R-CEL-1497784 https://reactome.org/PathwayBrowser/#/R-CEL-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Caenorhabditis elegans 15372 R-CEL-1497796 https://reactome.org/PathwayBrowser/#/R-CEL-1497796 BH2 binding can lead to eNOS uncoupling IEA Caenorhabditis elegans 15372 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 15372 R-CEL-202111 https://reactome.org/PathwayBrowser/#/R-CEL-202111 AKT1 phosphorylates eNOS IEA Caenorhabditis elegans 15372 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 15372 R-CEL-209823 https://reactome.org/PathwayBrowser/#/R-CEL-209823 Tyrosine is hydroxylated to dopa IEA Caenorhabditis elegans 15372 R-CEL-209828 https://reactome.org/PathwayBrowser/#/R-CEL-209828 Tryptophan is hydroxylated IEA Caenorhabditis elegans 15372 R-CEL-5696119 https://reactome.org/PathwayBrowser/#/R-CEL-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Caenorhabditis elegans 15372 R-CEL-71118 https://reactome.org/PathwayBrowser/#/R-CEL-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Caenorhabditis elegans 15372 R-CEL-71130 https://reactome.org/PathwayBrowser/#/R-CEL-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Caenorhabditis elegans 15372 R-CFA-1474146 https://reactome.org/PathwayBrowser/#/R-CFA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Canis familiaris 15372 R-CFA-1475414 https://reactome.org/PathwayBrowser/#/R-CFA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Canis familiaris 15372 R-CFA-203625 https://reactome.org/PathwayBrowser/#/R-CFA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Canis familiaris 15372 R-CFA-209823 https://reactome.org/PathwayBrowser/#/R-CFA-209823 Tyrosine is hydroxylated to dopa IEA Canis familiaris 15372 R-CFA-209828 https://reactome.org/PathwayBrowser/#/R-CFA-209828 Tryptophan is hydroxylated IEA Canis familiaris 15372 R-CFA-5696119 https://reactome.org/PathwayBrowser/#/R-CFA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Canis familiaris 15372 R-CFA-71118 https://reactome.org/PathwayBrowser/#/R-CFA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Canis familiaris 15372 R-CFA-71130 https://reactome.org/PathwayBrowser/#/R-CFA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Canis familiaris 15372 R-DDI-1474146 https://reactome.org/PathwayBrowser/#/R-DDI-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Dictyostelium discoideum 15372 R-DDI-1475414 https://reactome.org/PathwayBrowser/#/R-DDI-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Dictyostelium discoideum 15372 R-DDI-1497784 https://reactome.org/PathwayBrowser/#/R-DDI-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Dictyostelium discoideum 15372 R-DDI-1497796 https://reactome.org/PathwayBrowser/#/R-DDI-1497796 BH2 binding can lead to eNOS uncoupling IEA Dictyostelium discoideum 15372 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 15372 R-DDI-202111 https://reactome.org/PathwayBrowser/#/R-DDI-202111 AKT1 phosphorylates eNOS IEA Dictyostelium discoideum 15372 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 15372 R-DDI-202132 https://reactome.org/PathwayBrowser/#/R-DDI-202132 depalmitoylated eNOS translocates from plasma membrane IEA Dictyostelium discoideum 15372 R-DDI-203613 https://reactome.org/PathwayBrowser/#/R-DDI-203613 depalmitoylation of eNOS IEA Dictyostelium discoideum 15372 R-DDI-203680 https://reactome.org/PathwayBrowser/#/R-DDI-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Dictyostelium discoideum 15372 R-DDI-209823 https://reactome.org/PathwayBrowser/#/R-DDI-209823 Tyrosine is hydroxylated to dopa IEA Dictyostelium discoideum 15372 R-DDI-209828 https://reactome.org/PathwayBrowser/#/R-DDI-209828 Tryptophan is hydroxylated IEA Dictyostelium discoideum 15372 R-DDI-5696119 https://reactome.org/PathwayBrowser/#/R-DDI-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Dictyostelium discoideum 15372 R-DDI-71118 https://reactome.org/PathwayBrowser/#/R-DDI-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Dictyostelium discoideum 15372 R-DDI-71130 https://reactome.org/PathwayBrowser/#/R-DDI-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Dictyostelium discoideum 15372 R-DME-1474146 https://reactome.org/PathwayBrowser/#/R-DME-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Drosophila melanogaster 15372 R-DME-1475414 https://reactome.org/PathwayBrowser/#/R-DME-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Drosophila melanogaster 15372 R-DME-1497784 https://reactome.org/PathwayBrowser/#/R-DME-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Drosophila melanogaster 15372 R-DME-1497796 https://reactome.org/PathwayBrowser/#/R-DME-1497796 BH2 binding can lead to eNOS uncoupling IEA Drosophila melanogaster 15372 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 15372 R-DME-202111 https://reactome.org/PathwayBrowser/#/R-DME-202111 AKT1 phosphorylates eNOS IEA Drosophila melanogaster 15372 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 15372 R-DME-202132 https://reactome.org/PathwayBrowser/#/R-DME-202132 depalmitoylated eNOS translocates from plasma membrane IEA Drosophila melanogaster 15372 R-DME-203613 https://reactome.org/PathwayBrowser/#/R-DME-203613 depalmitoylation of eNOS IEA Drosophila melanogaster 15372 R-DME-203680 https://reactome.org/PathwayBrowser/#/R-DME-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Drosophila melanogaster 15372 R-DME-209823 https://reactome.org/PathwayBrowser/#/R-DME-209823 Tyrosine is hydroxylated to dopa IEA Drosophila melanogaster 15372 R-DME-209828 https://reactome.org/PathwayBrowser/#/R-DME-209828 Tryptophan is hydroxylated IEA Drosophila melanogaster 15372 R-DME-71118 https://reactome.org/PathwayBrowser/#/R-DME-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Drosophila melanogaster 15372 R-DME-71130 https://reactome.org/PathwayBrowser/#/R-DME-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Drosophila melanogaster 15372 R-DRE-1475414 https://reactome.org/PathwayBrowser/#/R-DRE-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Danio rerio 15372 R-DRE-203625 https://reactome.org/PathwayBrowser/#/R-DRE-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Danio rerio 15372 R-DRE-209823 https://reactome.org/PathwayBrowser/#/R-DRE-209823 Tyrosine is hydroxylated to dopa IEA Danio rerio 15372 R-DRE-209828 https://reactome.org/PathwayBrowser/#/R-DRE-209828 Tryptophan is hydroxylated IEA Danio rerio 15372 R-DRE-5696119 https://reactome.org/PathwayBrowser/#/R-DRE-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Danio rerio 15372 R-DRE-71118 https://reactome.org/PathwayBrowser/#/R-DRE-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Danio rerio 15372 R-DRE-71130 https://reactome.org/PathwayBrowser/#/R-DRE-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Danio rerio 15372 R-GGA-1474146 https://reactome.org/PathwayBrowser/#/R-GGA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Gallus gallus 15372 R-GGA-1475414 https://reactome.org/PathwayBrowser/#/R-GGA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Gallus gallus 15372 R-GGA-1497784 https://reactome.org/PathwayBrowser/#/R-GGA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Gallus gallus 15372 R-GGA-1497796 https://reactome.org/PathwayBrowser/#/R-GGA-1497796 BH2 binding can lead to eNOS uncoupling IEA Gallus gallus 15372 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 15372 R-GGA-202111 https://reactome.org/PathwayBrowser/#/R-GGA-202111 AKT1 phosphorylates eNOS IEA Gallus gallus 15372 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 15372 R-GGA-202132 https://reactome.org/PathwayBrowser/#/R-GGA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Gallus gallus 15372 R-GGA-203613 https://reactome.org/PathwayBrowser/#/R-GGA-203613 depalmitoylation of eNOS IEA Gallus gallus 15372 R-GGA-203625 https://reactome.org/PathwayBrowser/#/R-GGA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Gallus gallus 15372 R-GGA-209823 https://reactome.org/PathwayBrowser/#/R-GGA-209823 Tyrosine is hydroxylated to dopa IEA Gallus gallus 15372 R-GGA-209828 https://reactome.org/PathwayBrowser/#/R-GGA-209828 Tryptophan is hydroxylated IEA Gallus gallus 15372 R-GGA-5696119 https://reactome.org/PathwayBrowser/#/R-GGA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Gallus gallus 15372 R-GGA-71118 https://reactome.org/PathwayBrowser/#/R-GGA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Gallus gallus 15372 R-GGA-71130 https://reactome.org/PathwayBrowser/#/R-GGA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Gallus gallus 15372 R-HSA-1474146 https://reactome.org/PathwayBrowser/#/R-HSA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate TAS Homo sapiens 15372 R-HSA-1475414 https://reactome.org/PathwayBrowser/#/R-HSA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) TAS Homo sapiens 15372 R-HSA-1497784 https://reactome.org/PathwayBrowser/#/R-HSA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle TAS Homo sapiens 15372 R-HSA-1497794 https://reactome.org/PathwayBrowser/#/R-HSA-1497794 Salvage - BH2 is reduced to BH4 by DHFR IEA Homo sapiens 15372 R-HSA-1497796 https://reactome.org/PathwayBrowser/#/R-HSA-1497796 BH2 binding can lead to eNOS uncoupling TAS Homo sapiens 15372 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 15372 R-HSA-1497824 https://reactome.org/PathwayBrowser/#/R-HSA-1497824 BH4 is oxidised to the BH3 radical during the eNOS catalytic cycle TAS Homo sapiens 15372 R-HSA-1497855 https://reactome.org/PathwayBrowser/#/R-HSA-1497855 Ascorbate can reduce the BH3 radical back to BH4 TAS Homo sapiens 15372 R-HSA-1497866 https://reactome.org/PathwayBrowser/#/R-HSA-1497866 Peroxynitrite can oxidise BH4 to the BH3 radical TAS Homo sapiens 15372 R-HSA-1497883 https://reactome.org/PathwayBrowser/#/R-HSA-1497883 Ferrous iron reduces the BH3 radical back to BH4 TAS Homo sapiens 15372 R-HSA-202111 https://reactome.org/PathwayBrowser/#/R-HSA-202111 AKT1 phosphorylates eNOS TAS Homo sapiens 15372 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 15372 R-HSA-202132 https://reactome.org/PathwayBrowser/#/R-HSA-202132 depalmitoylated eNOS translocates from plasma membrane TAS Homo sapiens 15372 R-HSA-203613 https://reactome.org/PathwayBrowser/#/R-HSA-203613 depalmitoylation of eNOS TAS Homo sapiens 15372 R-HSA-203625 https://reactome.org/PathwayBrowser/#/R-HSA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane TAS Homo sapiens 15372 R-HSA-203680 https://reactome.org/PathwayBrowser/#/R-HSA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments TAS Homo sapiens 15372 R-HSA-209823 https://reactome.org/PathwayBrowser/#/R-HSA-209823 Tyrosine is hydroxylated to dopa TAS Homo sapiens 15372 R-HSA-209828 https://reactome.org/PathwayBrowser/#/R-HSA-209828 Tryptophan is hydroxylated TAS Homo sapiens 15372 R-HSA-5649483 https://reactome.org/PathwayBrowser/#/R-HSA-5649483 Defective PAH does not hydroxylate L-Phe to L-Tyr TAS Homo sapiens 15372 R-HSA-5696119 https://reactome.org/PathwayBrowser/#/R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol TAS Homo sapiens 15372 R-HSA-71118 https://reactome.org/PathwayBrowser/#/R-HSA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr TAS Homo sapiens 15372 R-HSA-71130 https://reactome.org/PathwayBrowser/#/R-HSA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ TAS Homo sapiens 15372 R-MMU-1474146 https://reactome.org/PathwayBrowser/#/R-MMU-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Mus musculus 15372 R-MMU-1475414 https://reactome.org/PathwayBrowser/#/R-MMU-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Mus musculus 15372 R-MMU-1497770 https://reactome.org/PathwayBrowser/#/R-MMU-1497770 Salvage - BH2 is reduced to BH4 by Dhfr TAS Mus musculus 15372 R-MMU-1497784 https://reactome.org/PathwayBrowser/#/R-MMU-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Mus musculus 15372 R-MMU-1497796 https://reactome.org/PathwayBrowser/#/R-MMU-1497796 BH2 binding can lead to eNOS uncoupling IEA Mus musculus 15372 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 15372 R-MMU-202111 https://reactome.org/PathwayBrowser/#/R-MMU-202111 AKT1 phosphorylates eNOS IEA Mus musculus 15372 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 15372 R-MMU-202132 https://reactome.org/PathwayBrowser/#/R-MMU-202132 depalmitoylated eNOS translocates from plasma membrane IEA Mus musculus 15372 R-MMU-203613 https://reactome.org/PathwayBrowser/#/R-MMU-203613 depalmitoylation of eNOS IEA Mus musculus 15372 R-MMU-203625 https://reactome.org/PathwayBrowser/#/R-MMU-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Mus musculus 15372 R-MMU-203680 https://reactome.org/PathwayBrowser/#/R-MMU-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Mus musculus 15372 R-MMU-209823 https://reactome.org/PathwayBrowser/#/R-MMU-209823 Tyrosine is hydroxylated to dopa IEA Mus musculus 15372 R-MMU-209828 https://reactome.org/PathwayBrowser/#/R-MMU-209828 Tryptophan is hydroxylated IEA Mus musculus 15372 R-MMU-5696119 https://reactome.org/PathwayBrowser/#/R-MMU-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Mus musculus 15372 R-MMU-71118 https://reactome.org/PathwayBrowser/#/R-MMU-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Mus musculus 15372 R-MMU-71130 https://reactome.org/PathwayBrowser/#/R-MMU-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Mus musculus 15372 R-PFA-1497784 https://reactome.org/PathwayBrowser/#/R-PFA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Plasmodium falciparum 15372 R-PFA-1497796 https://reactome.org/PathwayBrowser/#/R-PFA-1497796 BH2 binding can lead to eNOS uncoupling IEA Plasmodium falciparum 15372 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 15372 R-PFA-202111 https://reactome.org/PathwayBrowser/#/R-PFA-202111 AKT1 phosphorylates eNOS IEA Plasmodium falciparum 15372 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 15372 R-PFA-202132 https://reactome.org/PathwayBrowser/#/R-PFA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Plasmodium falciparum 15372 R-PFA-203680 https://reactome.org/PathwayBrowser/#/R-PFA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Plasmodium falciparum 15372 R-RNO-1474146 https://reactome.org/PathwayBrowser/#/R-RNO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Rattus norvegicus 15372 R-RNO-1475414 https://reactome.org/PathwayBrowser/#/R-RNO-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Rattus norvegicus 15372 R-RNO-1497784 https://reactome.org/PathwayBrowser/#/R-RNO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Rattus norvegicus 15372 R-RNO-1497796 https://reactome.org/PathwayBrowser/#/R-RNO-1497796 BH2 binding can lead to eNOS uncoupling IEA Rattus norvegicus 15372 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 15372 R-RNO-202111 https://reactome.org/PathwayBrowser/#/R-RNO-202111 AKT1 phosphorylates eNOS IEA Rattus norvegicus 15372 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 15372 R-RNO-202132 https://reactome.org/PathwayBrowser/#/R-RNO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Rattus norvegicus 15372 R-RNO-203613 https://reactome.org/PathwayBrowser/#/R-RNO-203613 depalmitoylation of eNOS IEA Rattus norvegicus 15372 R-RNO-203625 https://reactome.org/PathwayBrowser/#/R-RNO-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Rattus norvegicus 15372 R-RNO-203680 https://reactome.org/PathwayBrowser/#/R-RNO-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Rattus norvegicus 15372 R-RNO-209823 https://reactome.org/PathwayBrowser/#/R-RNO-209823 Tyrosine is hydroxylated to dopa IEA Rattus norvegicus 15372 R-RNO-209828 https://reactome.org/PathwayBrowser/#/R-RNO-209828 Tryptophan is hydroxylated IEA Rattus norvegicus 15372 R-RNO-5696119 https://reactome.org/PathwayBrowser/#/R-RNO-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Rattus norvegicus 15372 R-RNO-71118 https://reactome.org/PathwayBrowser/#/R-RNO-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Rattus norvegicus 15372 R-RNO-71130 https://reactome.org/PathwayBrowser/#/R-RNO-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Rattus norvegicus 15372 R-SCE-1474146 https://reactome.org/PathwayBrowser/#/R-SCE-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Saccharomyces cerevisiae 15372 R-SCE-1497784 https://reactome.org/PathwayBrowser/#/R-SCE-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Saccharomyces cerevisiae 15372 R-SCE-1497796 https://reactome.org/PathwayBrowser/#/R-SCE-1497796 BH2 binding can lead to eNOS uncoupling IEA Saccharomyces cerevisiae 15372 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 15372 R-SCE-202111 https://reactome.org/PathwayBrowser/#/R-SCE-202111 AKT1 phosphorylates eNOS IEA Saccharomyces cerevisiae 15372 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 15372 R-SCE-202132 https://reactome.org/PathwayBrowser/#/R-SCE-202132 depalmitoylated eNOS translocates from plasma membrane IEA Saccharomyces cerevisiae 15372 R-SCE-203613 https://reactome.org/PathwayBrowser/#/R-SCE-203613 depalmitoylation of eNOS IEA Saccharomyces cerevisiae 15372 R-SPO-1474146 https://reactome.org/PathwayBrowser/#/R-SPO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Schizosaccharomyces pombe 15372 R-SPO-1497784 https://reactome.org/PathwayBrowser/#/R-SPO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Schizosaccharomyces pombe 15372 R-SPO-1497796 https://reactome.org/PathwayBrowser/#/R-SPO-1497796 BH2 binding can lead to eNOS uncoupling IEA Schizosaccharomyces pombe 15372 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 15372 R-SPO-202111 https://reactome.org/PathwayBrowser/#/R-SPO-202111 AKT1 phosphorylates eNOS IEA Schizosaccharomyces pombe 15372 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 15372 R-SPO-202132 https://reactome.org/PathwayBrowser/#/R-SPO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Schizosaccharomyces pombe 15372 R-SPO-203613 https://reactome.org/PathwayBrowser/#/R-SPO-203613 depalmitoylation of eNOS IEA Schizosaccharomyces pombe 15372 R-SSC-1474146 https://reactome.org/PathwayBrowser/#/R-SSC-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Sus scrofa 15372 R-SSC-1475414 https://reactome.org/PathwayBrowser/#/R-SSC-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Sus scrofa 15372 R-SSC-1497784 https://reactome.org/PathwayBrowser/#/R-SSC-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Sus scrofa 15372 R-SSC-1497796 https://reactome.org/PathwayBrowser/#/R-SSC-1497796 BH2 binding can lead to eNOS uncoupling IEA Sus scrofa 15372 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 15372 R-SSC-202111 https://reactome.org/PathwayBrowser/#/R-SSC-202111 AKT1 phosphorylates eNOS IEA Sus scrofa 15372 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 15372 R-SSC-202132 https://reactome.org/PathwayBrowser/#/R-SSC-202132 depalmitoylated eNOS translocates from plasma membrane IEA Sus scrofa 15372 R-SSC-203613 https://reactome.org/PathwayBrowser/#/R-SSC-203613 depalmitoylation of eNOS IEA Sus scrofa 15372 R-SSC-203625 https://reactome.org/PathwayBrowser/#/R-SSC-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Sus scrofa 15372 R-SSC-203680 https://reactome.org/PathwayBrowser/#/R-SSC-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Sus scrofa 15372 R-SSC-209823 https://reactome.org/PathwayBrowser/#/R-SSC-209823 Tyrosine is hydroxylated to dopa IEA Sus scrofa 15372 R-SSC-209828 https://reactome.org/PathwayBrowser/#/R-SSC-209828 Tryptophan is hydroxylated IEA Sus scrofa 15372 R-SSC-5696119 https://reactome.org/PathwayBrowser/#/R-SSC-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Sus scrofa 15372 R-SSC-71118 https://reactome.org/PathwayBrowser/#/R-SSC-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Sus scrofa 15372 R-SSC-71130 https://reactome.org/PathwayBrowser/#/R-SSC-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Sus scrofa 15372 R-XTR-1474146 https://reactome.org/PathwayBrowser/#/R-XTR-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Xenopus tropicalis 15372 R-XTR-1475414 https://reactome.org/PathwayBrowser/#/R-XTR-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Xenopus tropicalis 15372 R-XTR-209823 https://reactome.org/PathwayBrowser/#/R-XTR-209823 Tyrosine is hydroxylated to dopa IEA Xenopus tropicalis 15372 R-XTR-5696119 https://reactome.org/PathwayBrowser/#/R-XTR-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Xenopus tropicalis 15372 R-XTR-71118 https://reactome.org/PathwayBrowser/#/R-XTR-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Xenopus tropicalis 15372 R-XTR-71130 https://reactome.org/PathwayBrowser/#/R-XTR-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Xenopus tropicalis 15374 R-BTA-209823 https://reactome.org/PathwayBrowser/#/R-BTA-209823 Tyrosine is hydroxylated to dopa IEA Bos taurus 15374 R-BTA-209828 https://reactome.org/PathwayBrowser/#/R-BTA-209828 Tryptophan is hydroxylated IEA Bos taurus 15374 R-BTA-71118 https://reactome.org/PathwayBrowser/#/R-BTA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Bos taurus 15374 R-BTA-71146 https://reactome.org/PathwayBrowser/#/R-BTA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Bos taurus 15374 R-CEL-209823 https://reactome.org/PathwayBrowser/#/R-CEL-209823 Tyrosine is hydroxylated to dopa IEA Caenorhabditis elegans 15374 R-CEL-209828 https://reactome.org/PathwayBrowser/#/R-CEL-209828 Tryptophan is hydroxylated IEA Caenorhabditis elegans 15374 R-CEL-71118 https://reactome.org/PathwayBrowser/#/R-CEL-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Caenorhabditis elegans 15374 R-CEL-71146 https://reactome.org/PathwayBrowser/#/R-CEL-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Caenorhabditis elegans 15374 R-CFA-209823 https://reactome.org/PathwayBrowser/#/R-CFA-209823 Tyrosine is hydroxylated to dopa IEA Canis familiaris 15374 R-CFA-209828 https://reactome.org/PathwayBrowser/#/R-CFA-209828 Tryptophan is hydroxylated IEA Canis familiaris 15374 R-CFA-71118 https://reactome.org/PathwayBrowser/#/R-CFA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Canis familiaris 15374 R-CFA-71146 https://reactome.org/PathwayBrowser/#/R-CFA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Canis familiaris 15374 R-DDI-209823 https://reactome.org/PathwayBrowser/#/R-DDI-209823 Tyrosine is hydroxylated to dopa IEA Dictyostelium discoideum 15374 R-DDI-209828 https://reactome.org/PathwayBrowser/#/R-DDI-209828 Tryptophan is hydroxylated IEA Dictyostelium discoideum 15374 R-DDI-71118 https://reactome.org/PathwayBrowser/#/R-DDI-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Dictyostelium discoideum 15374 R-DDI-71146 https://reactome.org/PathwayBrowser/#/R-DDI-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Dictyostelium discoideum 15374 R-DME-209823 https://reactome.org/PathwayBrowser/#/R-DME-209823 Tyrosine is hydroxylated to dopa IEA Drosophila melanogaster 15374 R-DME-209828 https://reactome.org/PathwayBrowser/#/R-DME-209828 Tryptophan is hydroxylated IEA Drosophila melanogaster 15374 R-DME-71118 https://reactome.org/PathwayBrowser/#/R-DME-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Drosophila melanogaster 15374 R-DME-71146 https://reactome.org/PathwayBrowser/#/R-DME-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Drosophila melanogaster 15374 R-DRE-209823 https://reactome.org/PathwayBrowser/#/R-DRE-209823 Tyrosine is hydroxylated to dopa IEA Danio rerio 15374 R-DRE-209828 https://reactome.org/PathwayBrowser/#/R-DRE-209828 Tryptophan is hydroxylated IEA Danio rerio 15374 R-DRE-71118 https://reactome.org/PathwayBrowser/#/R-DRE-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Danio rerio 15374 R-DRE-71146 https://reactome.org/PathwayBrowser/#/R-DRE-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Danio rerio 15374 R-GGA-209823 https://reactome.org/PathwayBrowser/#/R-GGA-209823 Tyrosine is hydroxylated to dopa IEA Gallus gallus 15374 R-GGA-209828 https://reactome.org/PathwayBrowser/#/R-GGA-209828 Tryptophan is hydroxylated IEA Gallus gallus 15374 R-GGA-71118 https://reactome.org/PathwayBrowser/#/R-GGA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Gallus gallus 15374 R-GGA-71146 https://reactome.org/PathwayBrowser/#/R-GGA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Gallus gallus 15374 R-HSA-209823 https://reactome.org/PathwayBrowser/#/R-HSA-209823 Tyrosine is hydroxylated to dopa TAS Homo sapiens 15374 R-HSA-209828 https://reactome.org/PathwayBrowser/#/R-HSA-209828 Tryptophan is hydroxylated TAS Homo sapiens 15374 R-HSA-71118 https://reactome.org/PathwayBrowser/#/R-HSA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr TAS Homo sapiens 15374 R-HSA-71146 https://reactome.org/PathwayBrowser/#/R-HSA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O TAS Homo sapiens 15374 R-MMU-209823 https://reactome.org/PathwayBrowser/#/R-MMU-209823 Tyrosine is hydroxylated to dopa IEA Mus musculus 15374 R-MMU-209828 https://reactome.org/PathwayBrowser/#/R-MMU-209828 Tryptophan is hydroxylated IEA Mus musculus 15374 R-MMU-71118 https://reactome.org/PathwayBrowser/#/R-MMU-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Mus musculus 15374 R-MMU-71146 https://reactome.org/PathwayBrowser/#/R-MMU-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Mus musculus 15374 R-PFA-71146 https://reactome.org/PathwayBrowser/#/R-PFA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Plasmodium falciparum 15374 R-RNO-209823 https://reactome.org/PathwayBrowser/#/R-RNO-209823 Tyrosine is hydroxylated to dopa IEA Rattus norvegicus 15374 R-RNO-209828 https://reactome.org/PathwayBrowser/#/R-RNO-209828 Tryptophan is hydroxylated IEA Rattus norvegicus 15374 R-RNO-71118 https://reactome.org/PathwayBrowser/#/R-RNO-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Rattus norvegicus 15374 R-RNO-71146 https://reactome.org/PathwayBrowser/#/R-RNO-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Rattus norvegicus 15374 R-SCE-71146 https://reactome.org/PathwayBrowser/#/R-SCE-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Saccharomyces cerevisiae 15374 R-SPO-71146 https://reactome.org/PathwayBrowser/#/R-SPO-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Schizosaccharomyces pombe 15374 R-SSC-209823 https://reactome.org/PathwayBrowser/#/R-SSC-209823 Tyrosine is hydroxylated to dopa IEA Sus scrofa 15374 R-SSC-209828 https://reactome.org/PathwayBrowser/#/R-SSC-209828 Tryptophan is hydroxylated IEA Sus scrofa 15374 R-SSC-71118 https://reactome.org/PathwayBrowser/#/R-SSC-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Sus scrofa 15374 R-SSC-71146 https://reactome.org/PathwayBrowser/#/R-SSC-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Sus scrofa 15374 R-XTR-209823 https://reactome.org/PathwayBrowser/#/R-XTR-209823 Tyrosine is hydroxylated to dopa IEA Xenopus tropicalis 15374 R-XTR-71118 https://reactome.org/PathwayBrowser/#/R-XTR-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Xenopus tropicalis 15374 R-XTR-71146 https://reactome.org/PathwayBrowser/#/R-XTR-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Xenopus tropicalis 15375 R-BTA-1497796 https://reactome.org/PathwayBrowser/#/R-BTA-1497796 BH2 binding can lead to eNOS uncoupling IEA Bos taurus 15375 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 15375 R-BTA-1497869 https://reactome.org/PathwayBrowser/#/R-BTA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Bos taurus 15375 R-BTA-5696119 https://reactome.org/PathwayBrowser/#/R-BTA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Bos taurus 15375 R-CEL-1497796 https://reactome.org/PathwayBrowser/#/R-CEL-1497796 BH2 binding can lead to eNOS uncoupling IEA Caenorhabditis elegans 15375 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 15375 R-CEL-5696119 https://reactome.org/PathwayBrowser/#/R-CEL-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Caenorhabditis elegans 15375 R-CFA-1497869 https://reactome.org/PathwayBrowser/#/R-CFA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Canis familiaris 15375 R-CFA-5696119 https://reactome.org/PathwayBrowser/#/R-CFA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Canis familiaris 15375 R-DDI-1497796 https://reactome.org/PathwayBrowser/#/R-DDI-1497796 BH2 binding can lead to eNOS uncoupling IEA Dictyostelium discoideum 15375 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 15375 R-DDI-1497869 https://reactome.org/PathwayBrowser/#/R-DDI-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Dictyostelium discoideum 15375 R-DDI-5696119 https://reactome.org/PathwayBrowser/#/R-DDI-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Dictyostelium discoideum 15375 R-DME-1497796 https://reactome.org/PathwayBrowser/#/R-DME-1497796 BH2 binding can lead to eNOS uncoupling IEA Drosophila melanogaster 15375 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 15375 R-DME-1497869 https://reactome.org/PathwayBrowser/#/R-DME-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Drosophila melanogaster 15375 R-DRE-1497869 https://reactome.org/PathwayBrowser/#/R-DRE-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Danio rerio 15375 R-DRE-5696119 https://reactome.org/PathwayBrowser/#/R-DRE-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Danio rerio 15375 R-GGA-1497796 https://reactome.org/PathwayBrowser/#/R-GGA-1497796 BH2 binding can lead to eNOS uncoupling IEA Gallus gallus 15375 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 15375 R-GGA-1497869 https://reactome.org/PathwayBrowser/#/R-GGA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Gallus gallus 15375 R-GGA-5696119 https://reactome.org/PathwayBrowser/#/R-GGA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Gallus gallus 15375 R-HSA-1497794 https://reactome.org/PathwayBrowser/#/R-HSA-1497794 Salvage - BH2 is reduced to BH4 by DHFR IEA Homo sapiens 15375 R-HSA-1497796 https://reactome.org/PathwayBrowser/#/R-HSA-1497796 BH2 binding can lead to eNOS uncoupling TAS Homo sapiens 15375 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 15375 R-HSA-1497863 https://reactome.org/PathwayBrowser/#/R-HSA-1497863 The BH3 radical can decay to dihydrobiopterin (BH2) TAS Homo sapiens 15375 R-HSA-1497869 https://reactome.org/PathwayBrowser/#/R-HSA-1497869 Salvage - Sepiapterin is reduced to BH2 TAS Homo sapiens 15375 R-HSA-5696119 https://reactome.org/PathwayBrowser/#/R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol TAS Homo sapiens 15375 R-MMU-1497770 https://reactome.org/PathwayBrowser/#/R-MMU-1497770 Salvage - BH2 is reduced to BH4 by Dhfr TAS Mus musculus 15375 R-MMU-1497796 https://reactome.org/PathwayBrowser/#/R-MMU-1497796 BH2 binding can lead to eNOS uncoupling IEA Mus musculus 15375 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 15375 R-MMU-1497869 https://reactome.org/PathwayBrowser/#/R-MMU-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Mus musculus 15375 R-MMU-5696119 https://reactome.org/PathwayBrowser/#/R-MMU-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Mus musculus 15375 R-PFA-1497796 https://reactome.org/PathwayBrowser/#/R-PFA-1497796 BH2 binding can lead to eNOS uncoupling IEA Plasmodium falciparum 15375 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 15375 R-RNO-1497796 https://reactome.org/PathwayBrowser/#/R-RNO-1497796 BH2 binding can lead to eNOS uncoupling IEA Rattus norvegicus 15375 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 15375 R-RNO-1497869 https://reactome.org/PathwayBrowser/#/R-RNO-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Rattus norvegicus 15375 R-RNO-5696119 https://reactome.org/PathwayBrowser/#/R-RNO-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Rattus norvegicus 15375 R-SCE-1497796 https://reactome.org/PathwayBrowser/#/R-SCE-1497796 BH2 binding can lead to eNOS uncoupling IEA Saccharomyces cerevisiae 15375 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 15375 R-SPO-1497796 https://reactome.org/PathwayBrowser/#/R-SPO-1497796 BH2 binding can lead to eNOS uncoupling IEA Schizosaccharomyces pombe 15375 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 15375 R-SSC-1497796 https://reactome.org/PathwayBrowser/#/R-SSC-1497796 BH2 binding can lead to eNOS uncoupling IEA Sus scrofa 15375 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 15375 R-SSC-1497869 https://reactome.org/PathwayBrowser/#/R-SSC-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Sus scrofa 15375 R-SSC-5696119 https://reactome.org/PathwayBrowser/#/R-SSC-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Sus scrofa 15375 R-XTR-1497869 https://reactome.org/PathwayBrowser/#/R-XTR-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Xenopus tropicalis 15375 R-XTR-5696119 https://reactome.org/PathwayBrowser/#/R-XTR-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Xenopus tropicalis 15377 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 15377 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 15377 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 15377 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 15377 R-BTA-109415 https://reactome.org/PathwayBrowser/#/R-BTA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Bos taurus 15377 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 15377 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 15377 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 15377 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 15377 R-BTA-111742 https://reactome.org/PathwayBrowser/#/R-BTA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 15377 R-BTA-111751 https://reactome.org/PathwayBrowser/#/R-BTA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 15377 R-BTA-111804 https://reactome.org/PathwayBrowser/#/R-BTA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 15377 R-BTA-111879 https://reactome.org/PathwayBrowser/#/R-BTA-111879 PIP2 hydrolysis IEA Bos taurus 15377 R-BTA-111883 https://reactome.org/PathwayBrowser/#/R-BTA-111883 Hydrolysis of phosphatidylcholine IEA Bos taurus 15377 R-BTA-111955 https://reactome.org/PathwayBrowser/#/R-BTA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Bos taurus 15377 R-BTA-111962 https://reactome.org/PathwayBrowser/#/R-BTA-111962 PDE4A,C,D hydrolyse cAMP IEA Bos taurus 15377 R-BTA-112037 https://reactome.org/PathwayBrowser/#/R-BTA-112037 Inactivation of PLC beta IEA Bos taurus 15377 R-BTA-113503 https://reactome.org/PathwayBrowser/#/R-BTA-113503 PP2A mediated localization of RB1 protein in chromatin IEA Bos taurus 15377 R-BTA-1169192 https://reactome.org/PathwayBrowser/#/R-BTA-1169192 PTP1B dephosphorylates GHR IEA Bos taurus 15377 R-BTA-1183128 https://reactome.org/PathwayBrowser/#/R-BTA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Bos taurus 15377 R-BTA-1237045 https://reactome.org/PathwayBrowser/#/R-BTA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Bos taurus 15377 R-BTA-1237047 https://reactome.org/PathwayBrowser/#/R-BTA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Bos taurus 15377 R-BTA-1237059 https://reactome.org/PathwayBrowser/#/R-BTA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Bos taurus 15377 R-BTA-1237081 https://reactome.org/PathwayBrowser/#/R-BTA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Bos taurus 15377 R-BTA-1237129 https://reactome.org/PathwayBrowser/#/R-BTA-1237129 Acireductone is created IEA Bos taurus 15377 R-BTA-1247910 https://reactome.org/PathwayBrowser/#/R-BTA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Bos taurus 15377 R-BTA-1247935 https://reactome.org/PathwayBrowser/#/R-BTA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Bos taurus 15377 R-BTA-1363274 https://reactome.org/PathwayBrowser/#/R-BTA-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Bos taurus 15377 R-BTA-1363276 https://reactome.org/PathwayBrowser/#/R-BTA-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Bos taurus 15377 R-BTA-1369065 https://reactome.org/PathwayBrowser/#/R-BTA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Bos taurus 15377 R-BTA-139906 https://reactome.org/PathwayBrowser/#/R-BTA-139906 Activation of BAD by calcineurin IEA Bos taurus 15377 R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 15377 R-BTA-140359 https://reactome.org/PathwayBrowser/#/R-BTA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Bos taurus 15377 R-BTA-141186 https://reactome.org/PathwayBrowser/#/R-BTA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Bos taurus 15377 R-BTA-141200 https://reactome.org/PathwayBrowser/#/R-BTA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Bos taurus 15377 R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus 15377 R-BTA-141341 https://reactome.org/PathwayBrowser/#/R-BTA-141341 SMOX-3 oxidises SPN to SPM IEA Bos taurus 15377 R-BTA-141348 https://reactome.org/PathwayBrowser/#/R-BTA-141348 PAO:FAD oxidises NASPM to PTCN IEA Bos taurus 15377 R-BTA-141351 https://reactome.org/PathwayBrowser/#/R-BTA-141351 PAOX:FAD oxidises NASPN to SPM IEA Bos taurus 15377 R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 15377 R-BTA-1454916 https://reactome.org/PathwayBrowser/#/R-BTA-1454916 The ABCC family mediates organic anion transport IEA Bos taurus 15377 R-BTA-1454928 https://reactome.org/PathwayBrowser/#/R-BTA-1454928 ABCG4 may mediate cholesterol efflux IEA Bos taurus 15377 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 15377 R-BTA-1467466 https://reactome.org/PathwayBrowser/#/R-BTA-1467466 ABCA4 mediates atRAL transport IEA Bos taurus 15377 R-BTA-1474146 https://reactome.org/PathwayBrowser/#/R-BTA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Bos taurus 15377 R-BTA-1475017 https://reactome.org/PathwayBrowser/#/R-BTA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Bos taurus 15377 R-BTA-1475022 https://reactome.org/PathwayBrowser/#/R-BTA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Bos taurus 15377 R-BTA-1475025 https://reactome.org/PathwayBrowser/#/R-BTA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Bos taurus 15377 R-BTA-1475026 https://reactome.org/PathwayBrowser/#/R-BTA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Bos taurus 15377 R-BTA-1475028 https://reactome.org/PathwayBrowser/#/R-BTA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Bos taurus 15377 R-BTA-1475032 https://reactome.org/PathwayBrowser/#/R-BTA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Bos taurus 15377 R-BTA-1475435 https://reactome.org/PathwayBrowser/#/R-BTA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Bos taurus 15377 R-BTA-1475436 https://reactome.org/PathwayBrowser/#/R-BTA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Bos taurus 15377 R-BTA-1482543 https://reactome.org/PathwayBrowser/#/R-BTA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Bos taurus 15377 R-BTA-1482604 https://reactome.org/PathwayBrowser/#/R-BTA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Bos taurus 15377 R-BTA-1482612 https://reactome.org/PathwayBrowser/#/R-BTA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 15377 R-BTA-1482656 https://reactome.org/PathwayBrowser/#/R-BTA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Bos taurus 15377 R-BTA-1482679 https://reactome.org/PathwayBrowser/#/R-BTA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Bos taurus 15377 R-BTA-1482685 https://reactome.org/PathwayBrowser/#/R-BTA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 15377 R-BTA-1482745 https://reactome.org/PathwayBrowser/#/R-BTA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Bos taurus 15377 R-BTA-1482759 https://reactome.org/PathwayBrowser/#/R-BTA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Bos taurus 15377 R-BTA-1482771 https://reactome.org/PathwayBrowser/#/R-BTA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Bos taurus 15377 R-BTA-1482776 https://reactome.org/PathwayBrowser/#/R-BTA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Bos taurus 15377 R-BTA-1482777 https://reactome.org/PathwayBrowser/#/R-BTA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Bos taurus 15377 R-BTA-1482811 https://reactome.org/PathwayBrowser/#/R-BTA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Bos taurus 15377 R-BTA-1482816 https://reactome.org/PathwayBrowser/#/R-BTA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Bos taurus 15377 R-BTA-1482825 https://reactome.org/PathwayBrowser/#/R-BTA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Bos taurus 15377 R-BTA-1482828 https://reactome.org/PathwayBrowser/#/R-BTA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Bos taurus 15377 R-BTA-1482847 https://reactome.org/PathwayBrowser/#/R-BTA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Bos taurus 15377 R-BTA-1482856 https://reactome.org/PathwayBrowser/#/R-BTA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Bos taurus 15377 R-BTA-1482862 https://reactome.org/PathwayBrowser/#/R-BTA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Bos taurus 15377 R-BTA-1482868 https://reactome.org/PathwayBrowser/#/R-BTA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Bos taurus 15377 R-BTA-1482884 https://reactome.org/PathwayBrowser/#/R-BTA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Bos taurus 15377 R-BTA-1482887 https://reactome.org/PathwayBrowser/#/R-BTA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Bos taurus 15377 R-BTA-1482897 https://reactome.org/PathwayBrowser/#/R-BTA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Bos taurus 15377 R-BTA-1482900 https://reactome.org/PathwayBrowser/#/R-BTA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Bos taurus 15377 R-BTA-1482907 https://reactome.org/PathwayBrowser/#/R-BTA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Bos taurus 15377 R-BTA-1482920 https://reactome.org/PathwayBrowser/#/R-BTA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Bos taurus 15377 R-BTA-1482932 https://reactome.org/PathwayBrowser/#/R-BTA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Bos taurus 15377 R-BTA-1483096 https://reactome.org/PathwayBrowser/#/R-BTA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Bos taurus 15377 R-BTA-1483159 https://reactome.org/PathwayBrowser/#/R-BTA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Bos taurus 15377 R-BTA-1483182 https://reactome.org/PathwayBrowser/#/R-BTA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Bos taurus 15377 R-BTA-1483203 https://reactome.org/PathwayBrowser/#/R-BTA-1483203 PA is dephosphorylated to DAG by LPIN IEA Bos taurus 15377 R-BTA-156526 https://reactome.org/PathwayBrowser/#/R-BTA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Bos taurus 15377 R-BTA-159425 https://reactome.org/PathwayBrowser/#/R-BTA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 15377 R-BTA-159752 https://reactome.org/PathwayBrowser/#/R-BTA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Bos taurus 15377 R-BTA-159761 https://reactome.org/PathwayBrowser/#/R-BTA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Bos taurus 15377 R-BTA-159795 https://reactome.org/PathwayBrowser/#/R-BTA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Bos taurus 15377 R-BTA-159803 https://reactome.org/PathwayBrowser/#/R-BTA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Bos taurus 15377 R-BTA-159819 https://reactome.org/PathwayBrowser/#/R-BTA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Bos taurus 15377 R-BTA-159826 https://reactome.org/PathwayBrowser/#/R-BTA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Bos taurus 15377 R-BTA-1602368 https://reactome.org/PathwayBrowser/#/R-BTA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Bos taurus 15377 R-BTA-1602374 https://reactome.org/PathwayBrowser/#/R-BTA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Bos taurus 15377 R-BTA-1602377 https://reactome.org/PathwayBrowser/#/R-BTA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Bos taurus 15377 R-BTA-1602398 https://reactome.org/PathwayBrowser/#/R-BTA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Bos taurus 15377 R-BTA-1602399 https://reactome.org/PathwayBrowser/#/R-BTA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Bos taurus 15377 R-BTA-1602417 https://reactome.org/PathwayBrowser/#/R-BTA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Bos taurus 15377 R-BTA-1602446 https://reactome.org/PathwayBrowser/#/R-BTA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Bos taurus 15377 R-BTA-1605591 https://reactome.org/PathwayBrowser/#/R-BTA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Bos taurus 15377 R-BTA-1605595 https://reactome.org/PathwayBrowser/#/R-BTA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Bos taurus 15377 R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus 15377 R-BTA-1605632 https://reactome.org/PathwayBrowser/#/R-BTA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Bos taurus 15377 R-BTA-1605723 https://reactome.org/PathwayBrowser/#/R-BTA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Bos taurus 15377 R-BTA-1605724 https://reactome.org/PathwayBrowser/#/R-BTA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Bos taurus 15377 R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus 15377 R-BTA-1605768 https://reactome.org/PathwayBrowser/#/R-BTA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Bos taurus 15377 R-BTA-1605797 https://reactome.org/PathwayBrowser/#/R-BTA-1605797 SMPD1 hydrolyzes SPHM IEA Bos taurus 15377 R-BTA-1606273 https://reactome.org/PathwayBrowser/#/R-BTA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Bos taurus 15377 R-BTA-1606288 https://reactome.org/PathwayBrowser/#/R-BTA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Bos taurus 15377 R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus 15377 R-BTA-1606564 https://reactome.org/PathwayBrowser/#/R-BTA-1606564 GALC hydrolyzes GalCer IEA Bos taurus 15377 R-BTA-1606583 https://reactome.org/PathwayBrowser/#/R-BTA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Bos taurus 15377 R-BTA-1606602 https://reactome.org/PathwayBrowser/#/R-BTA-1606602 ASAH1 hydrolyzes ceramide IEA Bos taurus 15377 R-BTA-1606789 https://reactome.org/PathwayBrowser/#/R-BTA-1606789 ARSB hydrolyses DS IEA Bos taurus 15377 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 15377 R-BTA-1606839 https://reactome.org/PathwayBrowser/#/R-BTA-1606839 ARSC hydrolyzes steroid sulfates IEA Bos taurus 15377 R-BTA-1614524 https://reactome.org/PathwayBrowser/#/R-BTA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Bos taurus 15377 R-BTA-1614544 https://reactome.org/PathwayBrowser/#/R-BTA-1614544 Sulfite is oxidized to sulfate IEA Bos taurus 15377 R-BTA-1614583 https://reactome.org/PathwayBrowser/#/R-BTA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Bos taurus 15377 R-BTA-1614605 https://reactome.org/PathwayBrowser/#/R-BTA-1614605 Persulfide sulfur is dioxygenated IEA Bos taurus 15377 R-BTA-1614614 https://reactome.org/PathwayBrowser/#/R-BTA-1614614 Cysteine is degraded to serine and H2S IEA Bos taurus 15377 R-BTA-1614631 https://reactome.org/PathwayBrowser/#/R-BTA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Bos taurus 15377 R-BTA-162425 https://reactome.org/PathwayBrowser/#/R-BTA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Bos taurus 15377 R-BTA-162729 https://reactome.org/PathwayBrowser/#/R-BTA-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Bos taurus 15377 R-BTA-162857 https://reactome.org/PathwayBrowser/#/R-BTA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Bos taurus 15377 R-BTA-1630304 https://reactome.org/PathwayBrowser/#/R-BTA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Bos taurus 15377 R-BTA-1630306 https://reactome.org/PathwayBrowser/#/R-BTA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Bos taurus 15377 R-BTA-163120 https://reactome.org/PathwayBrowser/#/R-BTA-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Bos taurus 15377 R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 15377 R-BTA-1638032 https://reactome.org/PathwayBrowser/#/R-BTA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Bos taurus 15377 R-BTA-1638053 https://reactome.org/PathwayBrowser/#/R-BTA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Bos taurus 15377 R-BTA-163820 https://reactome.org/PathwayBrowser/#/R-BTA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Bos taurus 15377 R-BTA-1638821 https://reactome.org/PathwayBrowser/#/R-BTA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Bos taurus 15377 R-BTA-1640164 https://reactome.org/PathwayBrowser/#/R-BTA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Bos taurus 15377 R-BTA-164832 https://reactome.org/PathwayBrowser/#/R-BTA-164832 ATPase synthesizes ATP IEA Bos taurus 15377 R-BTA-1655453 https://reactome.org/PathwayBrowser/#/R-BTA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Bos taurus 15377 R-BTA-1667005 https://reactome.org/PathwayBrowser/#/R-BTA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Bos taurus 15377 R-BTA-1675795 https://reactome.org/PathwayBrowser/#/R-BTA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Bos taurus 15377 R-BTA-1675824 https://reactome.org/PathwayBrowser/#/R-BTA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Bos taurus 15377 R-BTA-1675836 https://reactome.org/PathwayBrowser/#/R-BTA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Bos taurus 15377 R-BTA-1675949 https://reactome.org/PathwayBrowser/#/R-BTA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Bos taurus 15377 R-BTA-1675988 https://reactome.org/PathwayBrowser/#/R-BTA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Bos taurus 15377 R-BTA-1675994 https://reactome.org/PathwayBrowser/#/R-BTA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Bos taurus 15377 R-BTA-1676005 https://reactome.org/PathwayBrowser/#/R-BTA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Bos taurus 15377 R-BTA-1676020 https://reactome.org/PathwayBrowser/#/R-BTA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Bos taurus 15377 R-BTA-1676065 https://reactome.org/PathwayBrowser/#/R-BTA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Bos taurus 15377 R-BTA-1676105 https://reactome.org/PathwayBrowser/#/R-BTA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Bos taurus 15377 R-BTA-1676114 https://reactome.org/PathwayBrowser/#/R-BTA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Bos taurus 15377 R-BTA-1676124 https://reactome.org/PathwayBrowser/#/R-BTA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Bos taurus 15377 R-BTA-1676141 https://reactome.org/PathwayBrowser/#/R-BTA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Bos taurus 15377 R-BTA-1676149 https://reactome.org/PathwayBrowser/#/R-BTA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Bos taurus 15377 R-BTA-1676162 https://reactome.org/PathwayBrowser/#/R-BTA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Bos taurus 15377 R-BTA-1676164 https://reactome.org/PathwayBrowser/#/R-BTA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Bos taurus 15377 R-BTA-1676174 https://reactome.org/PathwayBrowser/#/R-BTA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Bos taurus 15377 R-BTA-1676177 https://reactome.org/PathwayBrowser/#/R-BTA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Bos taurus 15377 R-BTA-1676203 https://reactome.org/PathwayBrowser/#/R-BTA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Bos taurus 15377 R-BTA-1676204 https://reactome.org/PathwayBrowser/#/R-BTA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Bos taurus 15377 R-BTA-1678650 https://reactome.org/PathwayBrowser/#/R-BTA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Bos taurus 15377 R-BTA-1678708 https://reactome.org/PathwayBrowser/#/R-BTA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Bos taurus 15377 R-BTA-1678716 https://reactome.org/PathwayBrowser/#/R-BTA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Bos taurus 15377 R-BTA-1678742 https://reactome.org/PathwayBrowser/#/R-BTA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Bos taurus 15377 R-BTA-1678854 https://reactome.org/PathwayBrowser/#/R-BTA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Bos taurus 15377 R-BTA-170153 https://reactome.org/PathwayBrowser/#/R-BTA-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Bos taurus 15377 R-BTA-170158 https://reactome.org/PathwayBrowser/#/R-BTA-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Bos taurus 15377 R-BTA-170161 https://reactome.org/PathwayBrowser/#/R-BTA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Bos taurus 15377 R-BTA-173597 https://reactome.org/PathwayBrowser/#/R-BTA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Bos taurus 15377 R-BTA-173739 https://reactome.org/PathwayBrowser/#/R-BTA-173739 Spontaneous hydrolysis of C3 thioester IEA Bos taurus 15377 R-BTA-174110 https://reactome.org/PathwayBrowser/#/R-BTA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Bos taurus 15377 R-BTA-174124 https://reactome.org/PathwayBrowser/#/R-BTA-174124 Dephosphorylation of phospho-Cdh1 IEA Bos taurus 15377 R-BTA-174391 https://reactome.org/PathwayBrowser/#/R-BTA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Bos taurus 15377 R-BTA-174401 https://reactome.org/PathwayBrowser/#/R-BTA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Bos taurus 15377 R-BTA-174438 https://reactome.org/PathwayBrowser/#/R-BTA-174438 Formation of the Flap Intermediate on the C-strand IEA Bos taurus 15377 R-BTA-174439 https://reactome.org/PathwayBrowser/#/R-BTA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Bos taurus 15377 R-BTA-176606 https://reactome.org/PathwayBrowser/#/R-BTA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Bos taurus 15377 R-BTA-177923 https://reactome.org/PathwayBrowser/#/R-BTA-177923 Sustained activation of SRC kinase by SHP2 IEA Bos taurus 15377 R-BTA-177924 https://reactome.org/PathwayBrowser/#/R-BTA-177924 Dephosphorylation of Gab1 by SHP2 IEA Bos taurus 15377 R-BTA-177926 https://reactome.org/PathwayBrowser/#/R-BTA-177926 Dephosphorylation of PAG by SHP2 IEA Bos taurus 15377 R-BTA-177935 https://reactome.org/PathwayBrowser/#/R-BTA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Bos taurus 15377 R-BTA-1793182 https://reactome.org/PathwayBrowser/#/R-BTA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Bos taurus 15377 R-BTA-1793186 https://reactome.org/PathwayBrowser/#/R-BTA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Bos taurus 15377 R-BTA-1793207 https://reactome.org/PathwayBrowser/#/R-BTA-1793207 ARSB hydrolyses C4S/C6S chains IEA Bos taurus 15377 R-BTA-1793209 https://reactome.org/PathwayBrowser/#/R-BTA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Bos taurus 15377 R-BTA-1855154 https://reactome.org/PathwayBrowser/#/R-BTA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 15377 R-BTA-1855159 https://reactome.org/PathwayBrowser/#/R-BTA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Bos taurus 15377 R-BTA-1855163 https://reactome.org/PathwayBrowser/#/R-BTA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Bos taurus 15377 R-BTA-1855165 https://reactome.org/PathwayBrowser/#/R-BTA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 15377 R-BTA-1855166 https://reactome.org/PathwayBrowser/#/R-BTA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Bos taurus 15377 R-BTA-1855171 https://reactome.org/PathwayBrowser/#/R-BTA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Bos taurus 15377 R-BTA-1855174 https://reactome.org/PathwayBrowser/#/R-BTA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Bos taurus 15377 R-BTA-1855177 https://reactome.org/PathwayBrowser/#/R-BTA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Bos taurus 15377 R-BTA-1855180 https://reactome.org/PathwayBrowser/#/R-BTA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Bos taurus 15377 R-BTA-1855198 https://reactome.org/PathwayBrowser/#/R-BTA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 15377 R-BTA-1855200 https://reactome.org/PathwayBrowser/#/R-BTA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Bos taurus 15377 R-BTA-1855202 https://reactome.org/PathwayBrowser/#/R-BTA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Bos taurus 15377 R-BTA-1855205 https://reactome.org/PathwayBrowser/#/R-BTA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Bos taurus 15377 R-BTA-1855208 https://reactome.org/PathwayBrowser/#/R-BTA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Bos taurus 15377 R-BTA-1855210 https://reactome.org/PathwayBrowser/#/R-BTA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 15377 R-BTA-1855211 https://reactome.org/PathwayBrowser/#/R-BTA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 15377 R-BTA-1855213 https://reactome.org/PathwayBrowser/#/R-BTA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Bos taurus 15377 R-BTA-1855214 https://reactome.org/PathwayBrowser/#/R-BTA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Bos taurus 15377 R-BTA-1855218 https://reactome.org/PathwayBrowser/#/R-BTA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Bos taurus 15377 R-BTA-1855219 https://reactome.org/PathwayBrowser/#/R-BTA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Bos taurus 15377 R-BTA-1855221 https://reactome.org/PathwayBrowser/#/R-BTA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Bos taurus 15377 R-BTA-1855222 https://reactome.org/PathwayBrowser/#/R-BTA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Bos taurus 15377 R-BTA-1855225 https://reactome.org/PathwayBrowser/#/R-BTA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Bos taurus 15377 R-BTA-1855232 https://reactome.org/PathwayBrowser/#/R-BTA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Bos taurus 15377 R-BTA-1861788 https://reactome.org/PathwayBrowser/#/R-BTA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Bos taurus 15377 R-BTA-1861789 https://reactome.org/PathwayBrowser/#/R-BTA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Bos taurus 15377 R-BTA-188979 https://reactome.org/PathwayBrowser/#/R-BTA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Bos taurus 15377 R-BTA-189053 https://reactome.org/PathwayBrowser/#/R-BTA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Bos taurus 15377 R-BTA-189062 https://reactome.org/PathwayBrowser/#/R-BTA-189062 lactose + H2O => D-glucose + D-galactose IEA Bos taurus 15377 R-BTA-189069 https://reactome.org/PathwayBrowser/#/R-BTA-189069 sucrose + H2O => glucose + fructose IEA Bos taurus 15377 R-BTA-189102 https://reactome.org/PathwayBrowser/#/R-BTA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Bos taurus 15377 R-BTA-189398 https://reactome.org/PathwayBrowser/#/R-BTA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Bos taurus 15377 R-BTA-189406 https://reactome.org/PathwayBrowser/#/R-BTA-189406 4 PBGs bind to form HMB IEA Bos taurus 15377 R-BTA-189421 https://reactome.org/PathwayBrowser/#/R-BTA-189421 CPO transforms COPRO3 to PPGEN9 IEA Bos taurus 15377 R-BTA-189439 https://reactome.org/PathwayBrowser/#/R-BTA-189439 ALAD condenses 2 dALAs to form PBG IEA Bos taurus 15377 R-BTA-189488 https://reactome.org/PathwayBrowser/#/R-BTA-189488 UROS transforms HMB to URO3 IEA Bos taurus 15377 R-BTA-191101 https://reactome.org/PathwayBrowser/#/R-BTA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Bos taurus 15377 R-BTA-191108 https://reactome.org/PathwayBrowser/#/R-BTA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Bos taurus 15377 R-BTA-191114 https://reactome.org/PathwayBrowser/#/R-BTA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Bos taurus 15377 R-BTA-191116 https://reactome.org/PathwayBrowser/#/R-BTA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Bos taurus 15377 R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 15377 R-BTA-191323 https://reactome.org/PathwayBrowser/#/R-BTA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Bos taurus 15377 R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 15377 R-BTA-191999 https://reactome.org/PathwayBrowser/#/R-BTA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Bos taurus 15377 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 15377 R-BTA-192054 https://reactome.org/PathwayBrowser/#/R-BTA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Bos taurus 15377 R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 15377 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 15377 R-BTA-192123 https://reactome.org/PathwayBrowser/#/R-BTA-192123 CYP27A1 27-hydroxylates CHOL IEA Bos taurus 15377 R-BTA-192178 https://reactome.org/PathwayBrowser/#/R-BTA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Bos taurus 15377 R-BTA-192331 https://reactome.org/PathwayBrowser/#/R-BTA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Bos taurus 15377 R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 15377 R-BTA-192422 https://reactome.org/PathwayBrowser/#/R-BTA-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Bos taurus 15377 R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 15377 R-BTA-192430 https://reactome.org/PathwayBrowser/#/R-BTA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 15377 R-BTA-192434 https://reactome.org/PathwayBrowser/#/R-BTA-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Bos taurus 15377 R-BTA-192475 https://reactome.org/PathwayBrowser/#/R-BTA-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Bos taurus 15377 R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 15377 R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 15377 R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 15377 R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 15377 R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 15377 R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 15377 R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 15377 R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 15377 R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 15377 R-BTA-193362 https://reactome.org/PathwayBrowser/#/R-BTA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Bos taurus 15377 R-BTA-193385 https://reactome.org/PathwayBrowser/#/R-BTA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Bos taurus 15377 R-BTA-193393 https://reactome.org/PathwayBrowser/#/R-BTA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Bos taurus 15377 R-BTA-193460 https://reactome.org/PathwayBrowser/#/R-BTA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Bos taurus 15377 R-BTA-193535 https://reactome.org/PathwayBrowser/#/R-BTA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Bos taurus 15377 R-BTA-193711 https://reactome.org/PathwayBrowser/#/R-BTA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 15377 R-BTA-193713 https://reactome.org/PathwayBrowser/#/R-BTA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Bos taurus 15377 R-BTA-193719 https://reactome.org/PathwayBrowser/#/R-BTA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 15377 R-BTA-193727 https://reactome.org/PathwayBrowser/#/R-BTA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 15377 R-BTA-193737 https://reactome.org/PathwayBrowser/#/R-BTA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Bos taurus 15377 R-BTA-193743 https://reactome.org/PathwayBrowser/#/R-BTA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 15377 R-BTA-193766 https://reactome.org/PathwayBrowser/#/R-BTA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 15377 R-BTA-193780 https://reactome.org/PathwayBrowser/#/R-BTA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Bos taurus 15377 R-BTA-193787 https://reactome.org/PathwayBrowser/#/R-BTA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Bos taurus 15377 R-BTA-193792 https://reactome.org/PathwayBrowser/#/R-BTA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Bos taurus 15377 R-BTA-193964 https://reactome.org/PathwayBrowser/#/R-BTA-193964 CYP21A2 21-hydroxylates PROG IEA Bos taurus 15377 R-BTA-193965 https://reactome.org/PathwayBrowser/#/R-BTA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Bos taurus 15377 R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 15377 R-BTA-193995 https://reactome.org/PathwayBrowser/#/R-BTA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Bos taurus 15377 R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 15377 R-BTA-194017 https://reactome.org/PathwayBrowser/#/R-BTA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Bos taurus 15377 R-BTA-194641 https://reactome.org/PathwayBrowser/#/R-BTA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15377 R-BTA-194669 https://reactome.org/PathwayBrowser/#/R-BTA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15377 R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 15377 R-BTA-195664 https://reactome.org/PathwayBrowser/#/R-BTA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Bos taurus 15377 R-BTA-196950 https://reactome.org/PathwayBrowser/#/R-BTA-196950 2xTRAP hydrolyzes FMN to RIB IEA Bos taurus 15377 R-BTA-196955 https://reactome.org/PathwayBrowser/#/R-BTA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Bos taurus 15377 R-BTA-197271 https://reactome.org/PathwayBrowser/#/R-BTA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Bos taurus 15377 R-BTA-199456 https://reactome.org/PathwayBrowser/#/R-BTA-199456 PTEN dephosphorylates PIP3 IEA Bos taurus 15377 R-BTA-199959 https://reactome.org/PathwayBrowser/#/R-BTA-199959 ERKs are inactivated by protein phosphatase 2A IEA Bos taurus 15377 R-BTA-2002466 https://reactome.org/PathwayBrowser/#/R-BTA-2002466 Formation of allysine by LOX IEA Bos taurus 15377 R-BTA-200661 https://reactome.org/PathwayBrowser/#/R-BTA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Bos taurus 15377 R-BTA-200740 https://reactome.org/PathwayBrowser/#/R-BTA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Bos taurus 15377 R-BTA-201035 https://reactome.org/PathwayBrowser/#/R-BTA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Bos taurus 15377 R-BTA-201790 https://reactome.org/PathwayBrowser/#/R-BTA-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Bos taurus 15377 R-BTA-202214 https://reactome.org/PathwayBrowser/#/R-BTA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Bos taurus 15377 R-BTA-2022368 https://reactome.org/PathwayBrowser/#/R-BTA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Bos taurus 15377 R-BTA-202237 https://reactome.org/PathwayBrowser/#/R-BTA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Bos taurus 15377 R-BTA-2022378 https://reactome.org/PathwayBrowser/#/R-BTA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Bos taurus 15377 R-BTA-2022379 https://reactome.org/PathwayBrowser/#/R-BTA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Bos taurus 15377 R-BTA-2022381 https://reactome.org/PathwayBrowser/#/R-BTA-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 15377 R-BTA-2022383 https://reactome.org/PathwayBrowser/#/R-BTA-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 15377 R-BTA-2022396 https://reactome.org/PathwayBrowser/#/R-BTA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Bos taurus 15377 R-BTA-2022398 https://reactome.org/PathwayBrowser/#/R-BTA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Bos taurus 15377 R-BTA-2022399 https://reactome.org/PathwayBrowser/#/R-BTA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Bos taurus 15377 R-BTA-2022403 https://reactome.org/PathwayBrowser/#/R-BTA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Bos taurus 15377 R-BTA-2022405 https://reactome.org/PathwayBrowser/#/R-BTA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 15377 R-BTA-2022411 https://reactome.org/PathwayBrowser/#/R-BTA-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 15377 R-BTA-2022412 https://reactome.org/PathwayBrowser/#/R-BTA-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Bos taurus 15377 R-BTA-2022887 https://reactome.org/PathwayBrowser/#/R-BTA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Bos taurus 15377 R-BTA-2023971 https://reactome.org/PathwayBrowser/#/R-BTA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 15377 R-BTA-2023973 https://reactome.org/PathwayBrowser/#/R-BTA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 15377 R-BTA-202407 https://reactome.org/PathwayBrowser/#/R-BTA-202407 PLC-gamma1 hydrolyses PIP2 IEA Bos taurus 15377 R-BTA-2028294 https://reactome.org/PathwayBrowser/#/R-BTA-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Bos taurus 15377 R-BTA-2029468 https://reactome.org/PathwayBrowser/#/R-BTA-2029468 Conversion of PA into DAG by PAP-1 IEA Bos taurus 15377 R-BTA-2029471 https://reactome.org/PathwayBrowser/#/R-BTA-2029471 Hydrolysis of PC to PA by PLD IEA Bos taurus 15377 R-BTA-2029475 https://reactome.org/PathwayBrowser/#/R-BTA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Bos taurus 15377 R-BTA-203797 https://reactome.org/PathwayBrowser/#/R-BTA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Bos taurus 15377 R-BTA-204169 https://reactome.org/PathwayBrowser/#/R-BTA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Bos taurus 15377 R-BTA-2046083 https://reactome.org/PathwayBrowser/#/R-BTA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Bos taurus 15377 R-BTA-2046084 https://reactome.org/PathwayBrowser/#/R-BTA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Bos taurus 15377 R-BTA-2046088 https://reactome.org/PathwayBrowser/#/R-BTA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Bos taurus 15377 R-BTA-2046089 https://reactome.org/PathwayBrowser/#/R-BTA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Bos taurus 15377 R-BTA-2046090 https://reactome.org/PathwayBrowser/#/R-BTA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 15377 R-BTA-2046092 https://reactome.org/PathwayBrowser/#/R-BTA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Bos taurus 15377 R-BTA-2046094 https://reactome.org/PathwayBrowser/#/R-BTA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Bos taurus 15377 R-BTA-2046095 https://reactome.org/PathwayBrowser/#/R-BTA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Bos taurus 15377 R-BTA-2046096 https://reactome.org/PathwayBrowser/#/R-BTA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Bos taurus 15377 R-BTA-2046097 https://reactome.org/PathwayBrowser/#/R-BTA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 15377 R-BTA-2046100 https://reactome.org/PathwayBrowser/#/R-BTA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Bos taurus 15377 R-BTA-204662 https://reactome.org/PathwayBrowser/#/R-BTA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Bos taurus 15377 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 15377 R-BTA-2065357 https://reactome.org/PathwayBrowser/#/R-BTA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Bos taurus 15377 R-BTA-2066778 https://reactome.org/PathwayBrowser/#/R-BTA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Bos taurus 15377 R-BTA-2066779 https://reactome.org/PathwayBrowser/#/R-BTA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Bos taurus 15377 R-BTA-2090037 https://reactome.org/PathwayBrowser/#/R-BTA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Bos taurus 15377 R-BTA-2090038 https://reactome.org/PathwayBrowser/#/R-BTA-2090038 NAGLU hydrolyses heparan chain(2) IEA Bos taurus 15377 R-BTA-2090043 https://reactome.org/PathwayBrowser/#/R-BTA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Bos taurus 15377 R-BTA-2090079 https://reactome.org/PathwayBrowser/#/R-BTA-2090079 GLB1 hydrolyses linker chain(2) IEA Bos taurus 15377 R-BTA-209055 https://reactome.org/PathwayBrowser/#/R-BTA-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Bos taurus 15377 R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 15377 R-BTA-209845 https://reactome.org/PathwayBrowser/#/R-BTA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Bos taurus 15377 R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 15377 R-BTA-209891 https://reactome.org/PathwayBrowser/#/R-BTA-209891 Dopamine is oxidised to noradrenaline IEA Bos taurus 15377 R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 15377 R-BTA-2105001 https://reactome.org/PathwayBrowser/#/R-BTA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Bos taurus 15377 R-BTA-211873 https://reactome.org/PathwayBrowser/#/R-BTA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Bos taurus 15377 R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 15377 R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 15377 R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 15377 R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 15377 R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 15377 R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 15377 R-BTA-211923 https://reactome.org/PathwayBrowser/#/R-BTA-211923 CYP26C1 4-hydroxylates 9cRA IEA Bos taurus 15377 R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 15377 R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 15377 R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 15377 R-BTA-211950 https://reactome.org/PathwayBrowser/#/R-BTA-211950 CYP24A1 24-hydroxylates CTL IEA Bos taurus 15377 R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 15377 R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 15377 R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 15377 R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 15377 R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 15377 R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 15377 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 15377 R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 15377 R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 15377 R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 15377 R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 15377 R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 15377 R-BTA-2130725 https://reactome.org/PathwayBrowser/#/R-BTA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Bos taurus 15377 R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 15377 R-BTA-2160492 https://reactome.org/PathwayBrowser/#/R-BTA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Bos taurus 15377 R-BTA-2160874 https://reactome.org/PathwayBrowser/#/R-BTA-2160874 HYAL1 hydrolyses (HA)50 IEA Bos taurus 15377 R-BTA-2161187 https://reactome.org/PathwayBrowser/#/R-BTA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Bos taurus 15377 R-BTA-2161195 https://reactome.org/PathwayBrowser/#/R-BTA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Bos taurus 15377 R-BTA-2161745 https://reactome.org/PathwayBrowser/#/R-BTA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Bos taurus 15377 R-BTA-2161792 https://reactome.org/PathwayBrowser/#/R-BTA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Bos taurus 15377 R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Bos taurus 15377 R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 15377 R-BTA-2161890 https://reactome.org/PathwayBrowser/#/R-BTA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Bos taurus 15377 R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Bos taurus 15377 R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 15377 R-BTA-2161951 https://reactome.org/PathwayBrowser/#/R-BTA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Bos taurus 15377 R-BTA-2161959 https://reactome.org/PathwayBrowser/#/R-BTA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Bos taurus 15377 R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Bos taurus 15377 R-BTA-2161999 https://reactome.org/PathwayBrowser/#/R-BTA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Bos taurus 15377 R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 15377 R-BTA-2162225 https://reactome.org/PathwayBrowser/#/R-BTA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Bos taurus 15377 R-BTA-2162226 https://reactome.org/PathwayBrowser/#/R-BTA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Bos taurus 15377 R-BTA-2162227 https://reactome.org/PathwayBrowser/#/R-BTA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Bos taurus 15377 R-BTA-216723 https://reactome.org/PathwayBrowser/#/R-BTA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Bos taurus 15377 R-BTA-216757 https://reactome.org/PathwayBrowser/#/R-BTA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Bos taurus 15377 R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 15377 R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 15377 R-BTA-2187401 https://reactome.org/PathwayBrowser/#/R-BTA-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Bos taurus 15377 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 15377 R-BTA-2393939 https://reactome.org/PathwayBrowser/#/R-BTA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 15377 R-BTA-2393954 https://reactome.org/PathwayBrowser/#/R-BTA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 15377 R-BTA-2395340 https://reactome.org/PathwayBrowser/#/R-BTA-2395340 Formation of hydroxyallysine by LOX IEA Bos taurus 15377 R-BTA-2395818 https://reactome.org/PathwayBrowser/#/R-BTA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Bos taurus 15377 R-BTA-2395849 https://reactome.org/PathwayBrowser/#/R-BTA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 15377 R-BTA-2395869 https://reactome.org/PathwayBrowser/#/R-BTA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 15377 R-BTA-2395872 https://reactome.org/PathwayBrowser/#/R-BTA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Bos taurus 15377 R-BTA-2395873 https://reactome.org/PathwayBrowser/#/R-BTA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Bos taurus 15377 R-BTA-2395876 https://reactome.org/PathwayBrowser/#/R-BTA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 15377 R-BTA-2395879 https://reactome.org/PathwayBrowser/#/R-BTA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 15377 R-BTA-2395965 https://reactome.org/PathwayBrowser/#/R-BTA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Bos taurus 15377 R-BTA-2408527 https://reactome.org/PathwayBrowser/#/R-BTA-2408527 SeO3(2-) is reduced to H2Se by TXNRD1 TAS Bos taurus 15377 R-BTA-2408551 https://reactome.org/PathwayBrowser/#/R-BTA-2408551 SeMet is converted to AdoSeMet by MAT IEA Bos taurus 15377 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 15377 R-BTA-2454118 https://reactome.org/PathwayBrowser/#/R-BTA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Bos taurus 15377 R-BTA-2465924 https://reactome.org/PathwayBrowser/#/R-BTA-2465924 OPN1LW binds 11cRAL IEA Bos taurus 15377 R-BTA-2466085 https://reactome.org/PathwayBrowser/#/R-BTA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Bos taurus 15377 R-BTA-2466767 https://reactome.org/PathwayBrowser/#/R-BTA-2466767 NRPE is a substrate for Abca4 TAS Bos taurus 15377 R-BTA-2509793 https://reactome.org/PathwayBrowser/#/R-BTA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Bos taurus 15377 R-BTA-2509816 https://reactome.org/PathwayBrowser/#/R-BTA-2509816 NUDT16 hydrolyses IDP to IMP IEA Bos taurus 15377 R-BTA-2509827 https://reactome.org/PathwayBrowser/#/R-BTA-2509827 ITPA hydrolyses ITP to IMP IEA Bos taurus 15377 R-BTA-2509831 https://reactome.org/PathwayBrowser/#/R-BTA-2509831 ITPA hydrolyses XTP to XMP IEA Bos taurus 15377 R-BTA-2509838 https://reactome.org/PathwayBrowser/#/R-BTA-2509838 ITPA hydrolyses dITP to dIMP IEA Bos taurus 15377 R-BTA-2529015 https://reactome.org/PathwayBrowser/#/R-BTA-2529015 Dephosphorylation of CK2-modified condensin I IEA Bos taurus 15377 R-BTA-2584246 https://reactome.org/PathwayBrowser/#/R-BTA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Bos taurus 15377 R-BTA-2632521 https://reactome.org/PathwayBrowser/#/R-BTA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Bos taurus 15377 R-BTA-265783 https://reactome.org/PathwayBrowser/#/R-BTA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Bos taurus 15377 R-BTA-266012 https://reactome.org/PathwayBrowser/#/R-BTA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Bos taurus 15377 R-BTA-266046 https://reactome.org/PathwayBrowser/#/R-BTA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Bos taurus 15377 R-BTA-266051 https://reactome.org/PathwayBrowser/#/R-BTA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Bos taurus 15377 R-BTA-266072 https://reactome.org/PathwayBrowser/#/R-BTA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Bos taurus 15377 R-BTA-266082 https://reactome.org/PathwayBrowser/#/R-BTA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Bos taurus 15377 R-BTA-2730847 https://reactome.org/PathwayBrowser/#/R-BTA-2730847 Hydrolysis of PIP2 by PLCG IEA Bos taurus 15377 R-BTA-2730849 https://reactome.org/PathwayBrowser/#/R-BTA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Bos taurus 15377 R-BTA-2855047 https://reactome.org/PathwayBrowser/#/R-BTA-2855047 Hydrolysis of internal thioester in C4b IEA Bos taurus 15377 R-BTA-2995330 https://reactome.org/PathwayBrowser/#/R-BTA-2995330 COX10 transforms heme to heme O IEA Bos taurus 15377 R-BTA-2995334 https://reactome.org/PathwayBrowser/#/R-BTA-2995334 COX15 transforms heme O to heme A IEA Bos taurus 15377 R-BTA-2995388 https://reactome.org/PathwayBrowser/#/R-BTA-2995388 PP2A dephosphorylates BANF1 IEA Bos taurus 15377 R-BTA-3002811 https://reactome.org/PathwayBrowser/#/R-BTA-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Bos taurus 15377 R-BTA-3095901 https://reactome.org/PathwayBrowser/#/R-BTA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Bos taurus 15377 R-BTA-3204311 https://reactome.org/PathwayBrowser/#/R-BTA-3204311 AOX1 oxidises PXL to PDXate IEA Bos taurus 15377 R-BTA-3215295 https://reactome.org/PathwayBrowser/#/R-BTA-3215295 USP7 deubiquitinates MDM2 IEA Bos taurus 15377 R-BTA-3215310 https://reactome.org/PathwayBrowser/#/R-BTA-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Bos taurus 15377 R-BTA-3247569 https://reactome.org/PathwayBrowser/#/R-BTA-3247569 PADI4 deiminates Histones IEA Bos taurus 15377 R-BTA-3262512 https://reactome.org/PathwayBrowser/#/R-BTA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Bos taurus 15377 R-BTA-3266566 https://reactome.org/PathwayBrowser/#/R-BTA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Bos taurus 15377 R-BTA-3322995 https://reactome.org/PathwayBrowser/#/R-BTA-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Bos taurus 15377 R-BTA-3323013 https://reactome.org/PathwayBrowser/#/R-BTA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 15377 R-BTA-3341296 https://reactome.org/PathwayBrowser/#/R-BTA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Bos taurus 15377 R-BTA-3341343 https://reactome.org/PathwayBrowser/#/R-BTA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Bos taurus 15377 R-BTA-3341397 https://reactome.org/PathwayBrowser/#/R-BTA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 15377 R-BTA-3343700 https://reactome.org/PathwayBrowser/#/R-BTA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 15377 R-BTA-3371467 https://reactome.org/PathwayBrowser/#/R-BTA-3371467 SIRT1 deacetylates HSF1 IEA Bos taurus 15377 R-BTA-350604 https://reactome.org/PathwayBrowser/#/R-BTA-350604 Agmatine + H2O <=> putrescine + urea IEA Bos taurus 15377 R-BTA-350901 https://reactome.org/PathwayBrowser/#/R-BTA-350901 Iodide is organified IEA Bos taurus 15377 R-BTA-3640872 https://reactome.org/PathwayBrowser/#/R-BTA-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Bos taurus 15377 R-BTA-3697882 https://reactome.org/PathwayBrowser/#/R-BTA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Bos taurus 15377 R-BTA-3697894 https://reactome.org/PathwayBrowser/#/R-BTA-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Bos taurus 15377 R-BTA-374909 https://reactome.org/PathwayBrowser/#/R-BTA-374909 Catabolism of Noradrenaline IEA Bos taurus 15377 R-BTA-3769447 https://reactome.org/PathwayBrowser/#/R-BTA-3769447 HDAC1:2-containing complex deacetylate histones IEA Bos taurus 15377 R-BTA-377643 https://reactome.org/PathwayBrowser/#/R-BTA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Bos taurus 15377 R-BTA-3777129 https://reactome.org/PathwayBrowser/#/R-BTA-3777129 HDAC3 containing complexes deacetylate histone IEA Bos taurus 15377 R-BTA-3781011 https://reactome.org/PathwayBrowser/#/R-BTA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Bos taurus 15377 R-BTA-3781018 https://reactome.org/PathwayBrowser/#/R-BTA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Bos taurus 15377 R-BTA-3782637 https://reactome.org/PathwayBrowser/#/R-BTA-3782637 HDAC8 deacetylates histones IEA Bos taurus 15377 R-BTA-3782655 https://reactome.org/PathwayBrowser/#/R-BTA-3782655 HDAC10 deacetylates histone IEA Bos taurus 15377 R-BTA-379382 https://reactome.org/PathwayBrowser/#/R-BTA-379382 MAOA:FAD deaminates DA to DOPAC IEA Bos taurus 15377 R-BTA-379395 https://reactome.org/PathwayBrowser/#/R-BTA-379395 MAOA:FAD deaminates 3MT to HVA IEA Bos taurus 15377 R-BTA-380949 https://reactome.org/PathwayBrowser/#/R-BTA-380949 AMPK is dephosphorylated IEA Bos taurus 15377 R-BTA-382560 https://reactome.org/PathwayBrowser/#/R-BTA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Bos taurus 15377 R-BTA-382575 https://reactome.org/PathwayBrowser/#/R-BTA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Bos taurus 15377 R-BTA-383190 https://reactome.org/PathwayBrowser/#/R-BTA-383190 HCO3- transport through ion channel IEA Bos taurus 15377 R-BTA-389821 https://reactome.org/PathwayBrowser/#/R-BTA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Bos taurus 15377 R-BTA-389862 https://reactome.org/PathwayBrowser/#/R-BTA-389862 Conversion of glyoxylate to oxalate IEA Bos taurus 15377 R-BTA-389986 https://reactome.org/PathwayBrowser/#/R-BTA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Bos taurus 15377 R-BTA-390252 https://reactome.org/PathwayBrowser/#/R-BTA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Bos taurus 15377 R-BTA-390304 https://reactome.org/PathwayBrowser/#/R-BTA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Bos taurus 15377 R-BTA-399998 https://reactome.org/PathwayBrowser/#/R-BTA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Bos taurus 15377 R-BTA-4084976 https://reactome.org/PathwayBrowser/#/R-BTA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Bos taurus 15377 R-BTA-4084989 https://reactome.org/PathwayBrowser/#/R-BTA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Bos taurus 15377 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 15377 R-BTA-4084999 https://reactome.org/PathwayBrowser/#/R-BTA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 15377 R-BTA-4085021 https://reactome.org/PathwayBrowser/#/R-BTA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Bos taurus 15377 R-BTA-4085029 https://reactome.org/PathwayBrowser/#/R-BTA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 15377 R-BTA-4086392 https://reactome.org/PathwayBrowser/#/R-BTA-4086392 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 15377 R-BTA-4088141 https://reactome.org/PathwayBrowser/#/R-BTA-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Bos taurus 15377 R-BTA-4093339 https://reactome.org/PathwayBrowser/#/R-BTA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Bos taurus 15377 R-BTA-416559 https://reactome.org/PathwayBrowser/#/R-BTA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Bos taurus 15377 R-BTA-418553 https://reactome.org/PathwayBrowser/#/R-BTA-418553 cAMP degradation by Phosphodiesterases IEA Bos taurus 15377 R-BTA-426043 https://reactome.org/PathwayBrowser/#/R-BTA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Bos taurus 15377 R-BTA-428205 https://reactome.org/PathwayBrowser/#/R-BTA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Bos taurus 15377 R-BTA-428231 https://reactome.org/PathwayBrowser/#/R-BTA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Bos taurus 15377 R-BTA-428259 https://reactome.org/PathwayBrowser/#/R-BTA-428259 DEGS1 dehydrogenates dihydroceramide IEA Bos taurus 15377 R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 15377 R-BTA-428262 https://reactome.org/PathwayBrowser/#/R-BTA-428262 ACER3 hydrolyzes phytoceramide IEA Bos taurus 15377 R-BTA-428664 https://reactome.org/PathwayBrowser/#/R-BTA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Bos taurus 15377 R-BTA-428690 https://reactome.org/PathwayBrowser/#/R-BTA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Bos taurus 15377 R-BTA-428696 https://reactome.org/PathwayBrowser/#/R-BTA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Bos taurus 15377 R-BTA-429157 https://reactome.org/PathwayBrowser/#/R-BTA-429157 ABCC4 accumulation of dense granule contents IEA Bos taurus 15377 R-BTA-429730 https://reactome.org/PathwayBrowser/#/R-BTA-429730 PPM1L dephosphorylates multiphospho-CERT1-2 IEA Bos taurus 15377 R-BTA-429860 https://reactome.org/PathwayBrowser/#/R-BTA-429860 DCP1-DCP2 complex decaps mRNA IEA Bos taurus 15377 R-BTA-429955 https://reactome.org/PathwayBrowser/#/R-BTA-429955 CCR4-NOT complex deadenylates mRNA IEA Bos taurus 15377 R-BTA-429961 https://reactome.org/PathwayBrowser/#/R-BTA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Bos taurus 15377 R-BTA-429992 https://reactome.org/PathwayBrowser/#/R-BTA-429992 PARN deadenylates mRNA IEA Bos taurus 15377 R-BTA-430021 https://reactome.org/PathwayBrowser/#/R-BTA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Bos taurus 15377 R-BTA-430028 https://reactome.org/PathwayBrowser/#/R-BTA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Bos taurus 15377 R-BTA-432010 https://reactome.org/PathwayBrowser/#/R-BTA-432010 Aquaporin-1 passively transports water into cell IEA Bos taurus 15377 R-BTA-432054 https://reactome.org/PathwayBrowser/#/R-BTA-432054 Aquaporin-1 passively transports water out of cell IEA Bos taurus 15377 R-BTA-432065 https://reactome.org/PathwayBrowser/#/R-BTA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Bos taurus 15377 R-BTA-432067 https://reactome.org/PathwayBrowser/#/R-BTA-432067 Aquaporin-4 passively transports water out of cell IEA Bos taurus 15377 R-BTA-4419948 https://reactome.org/PathwayBrowser/#/R-BTA-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Bos taurus 15377 R-BTA-445714 https://reactome.org/PathwayBrowser/#/R-BTA-445714 Aquaporin-3 passively transports water out of cell IEA Bos taurus 15377 R-BTA-446200 https://reactome.org/PathwayBrowser/#/R-BTA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Bos taurus 15377 R-BTA-449937 https://reactome.org/PathwayBrowser/#/R-BTA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Bos taurus 15377 R-BTA-452036 https://reactome.org/PathwayBrowser/#/R-BTA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Bos taurus 15377 R-BTA-4551451 https://reactome.org/PathwayBrowser/#/R-BTA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Bos taurus 15377 R-BTA-4641236 https://reactome.org/PathwayBrowser/#/R-BTA-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Bos taurus 15377 R-BTA-504054 https://reactome.org/PathwayBrowser/#/R-BTA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Bos taurus 15377 R-BTA-507868 https://reactome.org/PathwayBrowser/#/R-BTA-507868 Aquaporins passively transport water into cells IEA Bos taurus 15377 R-BTA-507870 https://reactome.org/PathwayBrowser/#/R-BTA-507870 Aquaporins passively transport water out of cells IEA Bos taurus 15377 R-BTA-508308 https://reactome.org/PathwayBrowser/#/R-BTA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Bos taurus 15377 R-BTA-5221130 https://reactome.org/PathwayBrowser/#/R-BTA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Bos taurus 15377 R-BTA-5223313 https://reactome.org/PathwayBrowser/#/R-BTA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Bos taurus 15377 R-BTA-5223317 https://reactome.org/PathwayBrowser/#/R-BTA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Bos taurus 15377 R-BTA-5251955 https://reactome.org/PathwayBrowser/#/R-BTA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Bos taurus 15377 R-BTA-5251959 https://reactome.org/PathwayBrowser/#/R-BTA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Bos taurus 15377 R-BTA-5251989 https://reactome.org/PathwayBrowser/#/R-BTA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Bos taurus 15377 R-BTA-5263614 https://reactome.org/PathwayBrowser/#/R-BTA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Bos taurus 15377 R-BTA-5263616 https://reactome.org/PathwayBrowser/#/R-BTA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Bos taurus 15377 R-BTA-5362459 https://reactome.org/PathwayBrowser/#/R-BTA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Bos taurus 15377 R-BTA-5362522 https://reactome.org/PathwayBrowser/#/R-BTA-5362522 ALDHs oxidise atRAL to atRA IEA Bos taurus 15377 R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 15377 R-BTA-5423647 https://reactome.org/PathwayBrowser/#/R-BTA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Bos taurus 15377 R-BTA-5423664 https://reactome.org/PathwayBrowser/#/R-BTA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Bos taurus 15377 R-BTA-5423672 https://reactome.org/PathwayBrowser/#/R-BTA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Bos taurus 15377 R-BTA-5423678 https://reactome.org/PathwayBrowser/#/R-BTA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Bos taurus 15377 R-BTA-5433072 https://reactome.org/PathwayBrowser/#/R-BTA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Bos taurus 15377 R-BTA-5433074 https://reactome.org/PathwayBrowser/#/R-BTA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Bos taurus 15377 R-BTA-548843 https://reactome.org/PathwayBrowser/#/R-BTA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Bos taurus 15377 R-BTA-5602295 https://reactome.org/PathwayBrowser/#/R-BTA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Bos taurus 15377 R-BTA-5603114 https://reactome.org/PathwayBrowser/#/R-BTA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Bos taurus 15377 R-BTA-5607735 https://reactome.org/PathwayBrowser/#/R-BTA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Bos taurus 15377 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 15377 R-BTA-5623513 https://reactome.org/PathwayBrowser/#/R-BTA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Bos taurus 15377 R-BTA-5628905 https://reactome.org/PathwayBrowser/#/R-BTA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Bos taurus 15377 R-BTA-5631885 https://reactome.org/PathwayBrowser/#/R-BTA-5631885 PRDX1 overoxidizes IEA Bos taurus 15377 R-BTA-5649705 https://reactome.org/PathwayBrowser/#/R-BTA-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Bos taurus 15377 R-BTA-5651828 https://reactome.org/PathwayBrowser/#/R-BTA-5651828 PARG dePARylates PARP1,PARP2 IEA Bos taurus 15377 R-BTA-5653786 https://reactome.org/PathwayBrowser/#/R-BTA-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Bos taurus 15377 R-BTA-5659861 https://reactome.org/PathwayBrowser/#/R-BTA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Bos taurus 15377 R-BTA-5662692 https://reactome.org/PathwayBrowser/#/R-BTA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Bos taurus 15377 R-BTA-5665809 https://reactome.org/PathwayBrowser/#/R-BTA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Bos taurus 15377 R-BTA-5672957 https://reactome.org/PathwayBrowser/#/R-BTA-5672957 PP2A dephosphorylates KSR1 IEA Bos taurus 15377 R-BTA-5672961 https://reactome.org/PathwayBrowser/#/R-BTA-5672961 PP2A dephosphorylates inactive RAFs IEA Bos taurus 15377 R-BTA-5675373 https://reactome.org/PathwayBrowser/#/R-BTA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Bos taurus 15377 R-BTA-5675376 https://reactome.org/PathwayBrowser/#/R-BTA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Bos taurus 15377 R-BTA-5675431 https://reactome.org/PathwayBrowser/#/R-BTA-5675431 PP2A dephosphorylates RAF1 IEA Bos taurus 15377 R-BTA-5675433 https://reactome.org/PathwayBrowser/#/R-BTA-5675433 PP5 dephosphorylates RAF1 S338 IEA Bos taurus 15377 R-BTA-5676637 https://reactome.org/PathwayBrowser/#/R-BTA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Bos taurus 15377 R-BTA-5678327 https://reactome.org/PathwayBrowser/#/R-BTA-5678327 MIOX oxidises Ins to GlcA IEA Bos taurus 15377 R-BTA-5678706 https://reactome.org/PathwayBrowser/#/R-BTA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Bos taurus 15377 R-BTA-5678863 https://reactome.org/PathwayBrowser/#/R-BTA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Bos taurus 15377 R-BTA-5679041 https://reactome.org/PathwayBrowser/#/R-BTA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 15377 R-BTA-5682285 https://reactome.org/PathwayBrowser/#/R-BTA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Bos taurus 15377 R-BTA-5683405 https://reactome.org/PathwayBrowser/#/R-BTA-5683405 PPP5C dephosphorylates TP53BP1 IEA Bos taurus 15377 R-BTA-5683714 https://reactome.org/PathwayBrowser/#/R-BTA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Bos taurus 15377 R-BTA-5683967 https://reactome.org/PathwayBrowser/#/R-BTA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Bos taurus 15377 R-BTA-5684864 https://reactome.org/PathwayBrowser/#/R-BTA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Bos taurus 15377 R-BTA-5685902 https://reactome.org/PathwayBrowser/#/R-BTA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Bos taurus 15377 R-BTA-5685994 https://reactome.org/PathwayBrowser/#/R-BTA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Bos taurus 15377 R-BTA-5687464 https://reactome.org/PathwayBrowser/#/R-BTA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Bos taurus 15377 R-BTA-5687664 https://reactome.org/PathwayBrowser/#/R-BTA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Bos taurus 15377 R-BTA-5687758 https://reactome.org/PathwayBrowser/#/R-BTA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Bos taurus 15377 R-BTA-5688797 https://reactome.org/PathwayBrowser/#/R-BTA-5688797 ATXN3 family cleave Ub chains IEA Bos taurus 15377 R-BTA-5688837 https://reactome.org/PathwayBrowser/#/R-BTA-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Bos taurus 15377 R-BTA-5689000 https://reactome.org/PathwayBrowser/#/R-BTA-5689000 AADAC deacetylates PHEN IEA Bos taurus 15377 R-BTA-5689950 https://reactome.org/PathwayBrowser/#/R-BTA-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Bos taurus 15377 R-BTA-5689973 https://reactome.org/PathwayBrowser/#/R-BTA-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Bos taurus 15377 R-BTA-5690042 https://reactome.org/PathwayBrowser/#/R-BTA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 15377 R-BTA-5690043 https://reactome.org/PathwayBrowser/#/R-BTA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 15377 R-BTA-5690046 https://reactome.org/PathwayBrowser/#/R-BTA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Bos taurus 15377 R-BTA-5690066 https://reactome.org/PathwayBrowser/#/R-BTA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 15377 R-BTA-5690080 https://reactome.org/PathwayBrowser/#/R-BTA-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Bos taurus 15377 R-BTA-5690152 https://reactome.org/PathwayBrowser/#/R-BTA-5690152 USP5 cleaves polyubiquitin IEA Bos taurus 15377 R-BTA-5690157 https://reactome.org/PathwayBrowser/#/R-BTA-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Bos taurus 15377 R-BTA-5690159 https://reactome.org/PathwayBrowser/#/R-BTA-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Bos taurus 15377 R-BTA-5690196 https://reactome.org/PathwayBrowser/#/R-BTA-5690196 USP8 deubiquitinates RNF128 IEA Bos taurus 15377 R-BTA-5690319 https://reactome.org/PathwayBrowser/#/R-BTA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Bos taurus 15377 R-BTA-5690517 https://reactome.org/PathwayBrowser/#/R-BTA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Bos taurus 15377 R-BTA-5690565 https://reactome.org/PathwayBrowser/#/R-BTA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Bos taurus 15377 R-BTA-5690759 https://reactome.org/PathwayBrowser/#/R-BTA-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Bos taurus 15377 R-BTA-5690790 https://reactome.org/PathwayBrowser/#/R-BTA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Bos taurus 15377 R-BTA-5690808 https://reactome.org/PathwayBrowser/#/R-BTA-5690808 UCHL3, SENP8 cleave NEDD8 IEA Bos taurus 15377 R-BTA-5690856 https://reactome.org/PathwayBrowser/#/R-BTA-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Bos taurus 15377 R-BTA-5690870 https://reactome.org/PathwayBrowser/#/R-BTA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Bos taurus 15377 R-BTA-5691381 https://reactome.org/PathwayBrowser/#/R-BTA-5691381 MYSM1 deubiquitinates Histone H2A IEA Bos taurus 15377 R-BTA-5691411 https://reactome.org/PathwayBrowser/#/R-BTA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Bos taurus 15377 R-BTA-5691439 https://reactome.org/PathwayBrowser/#/R-BTA-5691439 BRISC complex deubiquitinates NLRP3 IEA Bos taurus 15377 R-BTA-5691507 https://reactome.org/PathwayBrowser/#/R-BTA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Bos taurus 15377 R-BTA-5691512 https://reactome.org/PathwayBrowser/#/R-BTA-5691512 APEH hydrolyses NAc-Ser-protein IEA Bos taurus 15377 R-BTA-5692261 https://reactome.org/PathwayBrowser/#/R-BTA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Bos taurus 15377 R-BTA-5692283 https://reactome.org/PathwayBrowser/#/R-BTA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Bos taurus 15377 R-BTA-5692462 https://reactome.org/PathwayBrowser/#/R-BTA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Bos taurus 15377 R-BTA-5692480 https://reactome.org/PathwayBrowser/#/R-BTA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Bos taurus 15377 R-BTA-5692754 https://reactome.org/PathwayBrowser/#/R-BTA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Bos taurus 15377 R-BTA-5693153 https://reactome.org/PathwayBrowser/#/R-BTA-5693153 PPM1K dephosphorylates p-BCKDH IEA Bos taurus 15377 R-BTA-5693346 https://reactome.org/PathwayBrowser/#/R-BTA-5693346 CECRI deaminates Ade-Rib to Ino IEA Bos taurus 15377 R-BTA-5693373 https://reactome.org/PathwayBrowser/#/R-BTA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Bos taurus 15377 R-BTA-5693608 https://reactome.org/PathwayBrowser/#/R-BTA-5693608 Initial resection of double-strand break ends IEA Bos taurus 15377 R-BTA-5693691 https://reactome.org/PathwayBrowser/#/R-BTA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Bos taurus 15377 R-BTA-5693724 https://reactome.org/PathwayBrowser/#/R-BTA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Bos taurus 15377 R-BTA-5693742 https://reactome.org/PathwayBrowser/#/R-BTA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Bos taurus 15377 R-BTA-5693761 https://reactome.org/PathwayBrowser/#/R-BTA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Bos taurus 15377 R-BTA-5693807 https://reactome.org/PathwayBrowser/#/R-BTA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Bos taurus 15377 R-BTA-5694077 https://reactome.org/PathwayBrowser/#/R-BTA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Bos taurus 15377 R-BTA-5694109 https://reactome.org/PathwayBrowser/#/R-BTA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Bos taurus 15377 R-BTA-5694126 https://reactome.org/PathwayBrowser/#/R-BTA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Bos taurus 15377 R-BTA-5694137 https://reactome.org/PathwayBrowser/#/R-BTA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Bos taurus 15377 R-BTA-5694421 https://reactome.org/PathwayBrowser/#/R-BTA-5694421 PP6 dephosphorylates SEC24 IEA Bos taurus 15377 R-BTA-5694462 https://reactome.org/PathwayBrowser/#/R-BTA-5694462 ABHD6,12 hydrolyse 3AG IEA Bos taurus 15377 R-BTA-5694485 https://reactome.org/PathwayBrowser/#/R-BTA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Bos taurus 15377 R-BTA-5694563 https://reactome.org/PathwayBrowser/#/R-BTA-5694563 ABHD10 hydrolyses MPAG IEA Bos taurus 15377 R-BTA-5694583 https://reactome.org/PathwayBrowser/#/R-BTA-5694583 ABHD4 hydrolyses NAPE IEA Bos taurus 15377 R-BTA-5695964 https://reactome.org/PathwayBrowser/#/R-BTA-5695964 ABHD14B hydrolyses PNPB IEA Bos taurus 15377 R-BTA-5696049 https://reactome.org/PathwayBrowser/#/R-BTA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 15377 R-BTA-5696080 https://reactome.org/PathwayBrowser/#/R-BTA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Bos taurus 15377 R-BTA-5696091 https://reactome.org/PathwayBrowser/#/R-BTA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Bos taurus 15377 R-BTA-5696101 https://reactome.org/PathwayBrowser/#/R-BTA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Bos taurus 15377 R-BTA-5696119 https://reactome.org/PathwayBrowser/#/R-BTA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Bos taurus 15377 R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 15377 R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 15377 R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 15377 R-BTA-5696197 https://reactome.org/PathwayBrowser/#/R-BTA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Bos taurus 15377 R-BTA-5696230 https://reactome.org/PathwayBrowser/#/R-BTA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Bos taurus 15377 R-BTA-5696365 https://reactome.org/PathwayBrowser/#/R-BTA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Bos taurus 15377 R-BTA-5696408 https://reactome.org/PathwayBrowser/#/R-BTA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Bos taurus 15377 R-BTA-5696415 https://reactome.org/PathwayBrowser/#/R-BTA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Bos taurus 15377 R-BTA-5696465 https://reactome.org/PathwayBrowser/#/R-BTA-5696465 USP45 deubiquitinates ERCC1 IEA Bos taurus 15377 R-BTA-5696534 https://reactome.org/PathwayBrowser/#/R-BTA-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Bos taurus 15377 R-BTA-5696564 https://reactome.org/PathwayBrowser/#/R-BTA-5696564 USP25 deubiquitinates DDX58 IEA Bos taurus 15377 R-BTA-5696600 https://reactome.org/PathwayBrowser/#/R-BTA-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Bos taurus 15377 R-BTA-5696605 https://reactome.org/PathwayBrowser/#/R-BTA-5696605 USP12, USP26 deubiquitinate AR IEA Bos taurus 15377 R-BTA-5696627 https://reactome.org/PathwayBrowser/#/R-BTA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Bos taurus 15377 R-BTA-5696872 https://reactome.org/PathwayBrowser/#/R-BTA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Bos taurus 15377 R-BTA-5696914 https://reactome.org/PathwayBrowser/#/R-BTA-5696914 USP28 deubiquitinates CLSPN and MYC IEA Bos taurus 15377 R-BTA-5696945 https://reactome.org/PathwayBrowser/#/R-BTA-5696945 USP33 deubiquitinates CCP110,ARRB IEA Bos taurus 15377 R-BTA-5696947 https://reactome.org/PathwayBrowser/#/R-BTA-5696947 USP47 deubiquitinates POLB IEA Bos taurus 15377 R-BTA-5696958 https://reactome.org/PathwayBrowser/#/R-BTA-5696958 USP44 deubiquitinates CDC20 IEA Bos taurus 15377 R-BTA-5696960 https://reactome.org/PathwayBrowser/#/R-BTA-5696960 USP49 deubiquitinates H2B IEA Bos taurus 15377 R-BTA-5696968 https://reactome.org/PathwayBrowser/#/R-BTA-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Bos taurus 15377 R-BTA-5696997 https://reactome.org/PathwayBrowser/#/R-BTA-5696997 USP24 deubiquitinates DDB2 IEA Bos taurus 15377 R-BTA-5697009 https://reactome.org/PathwayBrowser/#/R-BTA-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Bos taurus 15377 R-BTA-6781764 https://reactome.org/PathwayBrowser/#/R-BTA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Bos taurus 15377 R-BTA-6781779 https://reactome.org/PathwayBrowser/#/R-BTA-6781779 USP13 deubiquitinates BECN1,USP10 IEA Bos taurus 15377 R-BTA-6781814 https://reactome.org/PathwayBrowser/#/R-BTA-6781814 USP19 deubiquitinates RNF123 IEA Bos taurus 15377 R-BTA-6781897 https://reactome.org/PathwayBrowser/#/R-BTA-6781897 USP11 deubiquitinates NFKBIA IEA Bos taurus 15377 R-BTA-6782069 https://reactome.org/PathwayBrowser/#/R-BTA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Bos taurus 15377 R-BTA-6782628 https://reactome.org/PathwayBrowser/#/R-BTA-6782628 USP8 deubiquitinates STAM2:HGS IEA Bos taurus 15377 R-BTA-6782820 https://reactome.org/PathwayBrowser/#/R-BTA-6782820 USP17 deubiquitinates SUDS3 IEA Bos taurus 15377 R-BTA-6783177 https://reactome.org/PathwayBrowser/#/R-BTA-6783177 USP21 deubiquitinates GATA3,IL33 IEA Bos taurus 15377 R-BTA-6783221 https://reactome.org/PathwayBrowser/#/R-BTA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Bos taurus 15377 R-BTA-6784959 https://reactome.org/PathwayBrowser/#/R-BTA-6784959 BPHL hydrolyses VACV to ACV IEA Bos taurus 15377 R-BTA-6786190 https://reactome.org/PathwayBrowser/#/R-BTA-6786190 CMBL hydrolyses OM to OLMS IEA Bos taurus 15377 R-BTA-6786239 https://reactome.org/PathwayBrowser/#/R-BTA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Bos taurus 15377 R-BTA-6786421 https://reactome.org/PathwayBrowser/#/R-BTA-6786421 CHIA hydrolyses chitin IEA Bos taurus 15377 R-BTA-6786650 https://reactome.org/PathwayBrowser/#/R-BTA-6786650 DDHD1,2 hydrolyse PA IEA Bos taurus 15377 R-BTA-6787632 https://reactome.org/PathwayBrowser/#/R-BTA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Bos taurus 15377 R-BTA-6788295 https://reactome.org/PathwayBrowser/#/R-BTA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Bos taurus 15377 R-BTA-6788912 https://reactome.org/PathwayBrowser/#/R-BTA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Bos taurus 15377 R-BTA-6789031 https://reactome.org/PathwayBrowser/#/R-BTA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 15377 R-BTA-6789126 https://reactome.org/PathwayBrowser/#/R-BTA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 15377 R-BTA-6789310 https://reactome.org/PathwayBrowser/#/R-BTA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Bos taurus 15377 R-BTA-6792445 https://reactome.org/PathwayBrowser/#/R-BTA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Bos taurus 15377 R-BTA-6792863 https://reactome.org/PathwayBrowser/#/R-BTA-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Bos taurus 15377 R-BTA-6797627 https://reactome.org/PathwayBrowser/#/R-BTA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Bos taurus 15377 R-BTA-6797630 https://reactome.org/PathwayBrowser/#/R-BTA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Bos taurus 15377 R-BTA-6797653 https://reactome.org/PathwayBrowser/#/R-BTA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Bos taurus 15377 R-BTA-6797913 https://reactome.org/PathwayBrowser/#/R-BTA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Bos taurus 15377 R-BTA-6797955 https://reactome.org/PathwayBrowser/#/R-BTA-6797955 ALDH7A1 oxidises BETALD to BET IEA Bos taurus 15377 R-BTA-6799545 https://reactome.org/PathwayBrowser/#/R-BTA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Bos taurus 15377 R-BTA-6799581 https://reactome.org/PathwayBrowser/#/R-BTA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Bos taurus 15377 R-BTA-6799604 https://reactome.org/PathwayBrowser/#/R-BTA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Bos taurus 15377 R-BTA-6799695 https://reactome.org/PathwayBrowser/#/R-BTA-6799695 GPX5,6 reduce H2O2 to H2O IEA Bos taurus 15377 R-BTA-6799977 https://reactome.org/PathwayBrowser/#/R-BTA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Bos taurus 15377 R-BTA-6800198 https://reactome.org/PathwayBrowser/#/R-BTA-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Bos taurus 15377 R-BTA-6800200 https://reactome.org/PathwayBrowser/#/R-BTA-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Bos taurus 15377 R-BTA-6800299 https://reactome.org/PathwayBrowser/#/R-BTA-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Bos taurus 15377 R-BTA-6801462 https://reactome.org/PathwayBrowser/#/R-BTA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Bos taurus 15377 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 15377 R-BTA-6803789 https://reactome.org/PathwayBrowser/#/R-BTA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Bos taurus 15377 R-BTA-6805650 https://reactome.org/PathwayBrowser/#/R-BTA-6805650 MTA2-NuRD complex deacetylates TP53 IEA Bos taurus 15377 R-BTA-6807008 https://reactome.org/PathwayBrowser/#/R-BTA-6807008 PTPRJ dephosphorylates MET IEA Bos taurus 15377 R-BTA-6807027 https://reactome.org/PathwayBrowser/#/R-BTA-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Bos taurus 15377 R-BTA-6807053 https://reactome.org/PathwayBrowser/#/R-BTA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Bos taurus 15377 R-BTA-6807118 https://reactome.org/PathwayBrowser/#/R-BTA-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Bos taurus 15377 R-BTA-6807206 https://reactome.org/PathwayBrowser/#/R-BTA-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Bos taurus 15377 R-BTA-6807214 https://reactome.org/PathwayBrowser/#/R-BTA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Bos taurus 15377 R-BTA-6808464 https://reactome.org/PathwayBrowser/#/R-BTA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Bos taurus 15377 R-BTA-6808487 https://reactome.org/PathwayBrowser/#/R-BTA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 15377 R-BTA-6808496 https://reactome.org/PathwayBrowser/#/R-BTA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 15377 R-BTA-6809263 https://reactome.org/PathwayBrowser/#/R-BTA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Bos taurus 15377 R-BTA-6809287 https://reactome.org/PathwayBrowser/#/R-BTA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Bos taurus 15377 R-BTA-6809320 https://reactome.org/PathwayBrowser/#/R-BTA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Bos taurus 15377 R-BTA-6809325 https://reactome.org/PathwayBrowser/#/R-BTA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Bos taurus 15377 R-BTA-6809720 https://reactome.org/PathwayBrowser/#/R-BTA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Bos taurus 15377 R-BTA-6809777 https://reactome.org/PathwayBrowser/#/R-BTA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Bos taurus 15377 R-BTA-6809778 https://reactome.org/PathwayBrowser/#/R-BTA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Bos taurus 15377 R-BTA-6810076 https://reactome.org/PathwayBrowser/#/R-BTA-6810076 DDO oxidizes D-Asp to OA IEA Bos taurus 15377 R-BTA-6810410 https://reactome.org/PathwayBrowser/#/R-BTA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Bos taurus 15377 R-BTA-6810464 https://reactome.org/PathwayBrowser/#/R-BTA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Bos taurus 15377 R-BTA-6810472 https://reactome.org/PathwayBrowser/#/R-BTA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Bos taurus 15377 R-BTA-6810474 https://reactome.org/PathwayBrowser/#/R-BTA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Bos taurus 15377 R-BTA-6813720 https://reactome.org/PathwayBrowser/#/R-BTA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Bos taurus 15377 R-BTA-6813740 https://reactome.org/PathwayBrowser/#/R-BTA-6813740 GDE1 hydrolyzes GroPIns IEA Bos taurus 15377 R-BTA-6813749 https://reactome.org/PathwayBrowser/#/R-BTA-6813749 ALDH1A1 oxidises GA to DGA IEA Bos taurus 15377 R-BTA-6814254 https://reactome.org/PathwayBrowser/#/R-BTA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Bos taurus 15377 R-BTA-6814797 https://reactome.org/PathwayBrowser/#/R-BTA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Bos taurus 15377 R-BTA-69199 https://reactome.org/PathwayBrowser/#/R-BTA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Bos taurus 15377 R-BTA-70262 https://reactome.org/PathwayBrowser/#/R-BTA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Bos taurus 15377 R-BTA-70479 https://reactome.org/PathwayBrowser/#/R-BTA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Bos taurus 15377 R-BTA-70494 https://reactome.org/PathwayBrowser/#/R-BTA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Bos taurus 15377 R-BTA-70569 https://reactome.org/PathwayBrowser/#/R-BTA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Bos taurus 15377 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Bos taurus 15377 R-BTA-70599 https://reactome.org/PathwayBrowser/#/R-BTA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Bos taurus 15377 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Bos taurus 15377 R-BTA-70609 https://reactome.org/PathwayBrowser/#/R-BTA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Bos taurus 15377 R-BTA-70679 https://reactome.org/PathwayBrowser/#/R-BTA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Bos taurus 15377 R-BTA-70785 https://reactome.org/PathwayBrowser/#/R-BTA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Bos taurus 15377 R-BTA-70870 https://reactome.org/PathwayBrowser/#/R-BTA-70870 ECHS1 hydrates methacrylyl-CoA IEA Bos taurus 15377 R-BTA-70881 https://reactome.org/PathwayBrowser/#/R-BTA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Bos taurus 15377 R-BTA-70903 https://reactome.org/PathwayBrowser/#/R-BTA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Bos taurus 15377 R-BTA-70906 https://reactome.org/PathwayBrowser/#/R-BTA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Bos taurus 15377 R-BTA-70938 https://reactome.org/PathwayBrowser/#/R-BTA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Bos taurus 15377 R-BTA-70940 https://reactome.org/PathwayBrowser/#/R-BTA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Bos taurus 15377 R-BTA-70941 https://reactome.org/PathwayBrowser/#/R-BTA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Bos taurus 15377 R-BTA-70975 https://reactome.org/PathwayBrowser/#/R-BTA-70975 CS acetylates OA to citrate IEA Bos taurus 15377 R-BTA-70982 https://reactome.org/PathwayBrowser/#/R-BTA-70982 FH tetramer hydrates fumarate to L-malate IEA Bos taurus 15377 R-BTA-71146 https://reactome.org/PathwayBrowser/#/R-BTA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Bos taurus 15377 R-BTA-71181 https://reactome.org/PathwayBrowser/#/R-BTA-71181 FAH cleaves 4FAA IEA Bos taurus 15377 R-BTA-71200 https://reactome.org/PathwayBrowser/#/R-BTA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Bos taurus 15377 R-BTA-71217 https://reactome.org/PathwayBrowser/#/R-BTA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Bos taurus 15377 R-BTA-71260 https://reactome.org/PathwayBrowser/#/R-BTA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Bos taurus 15377 R-BTA-71296 https://reactome.org/PathwayBrowser/#/R-BTA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Bos taurus 15377 R-BTA-71660 https://reactome.org/PathwayBrowser/#/R-BTA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Bos taurus 15377 R-BTA-71676 https://reactome.org/PathwayBrowser/#/R-BTA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Bos taurus 15377 R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 15377 R-BTA-71723 https://reactome.org/PathwayBrowser/#/R-BTA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Bos taurus 15377 R-BTA-71732 https://reactome.org/PathwayBrowser/#/R-BTA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Bos taurus 15377 R-BTA-71825 https://reactome.org/PathwayBrowser/#/R-BTA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Bos taurus 15377 R-BTA-73571 https://reactome.org/PathwayBrowser/#/R-BTA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Bos taurus 15377 R-BTA-73577 https://reactome.org/PathwayBrowser/#/R-BTA-73577 CAD hexamer transforms L-Gln to CAP IEA Bos taurus 15377 R-BTA-73589 https://reactome.org/PathwayBrowser/#/R-BTA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Bos taurus 15377 R-BTA-73591 https://reactome.org/PathwayBrowser/#/R-BTA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Bos taurus 15377 R-BTA-73596 https://reactome.org/PathwayBrowser/#/R-BTA-73596 dCMP + H2O => dUMP + NH4+ IEA Bos taurus 15377 R-BTA-73608 https://reactome.org/PathwayBrowser/#/R-BTA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Bos taurus 15377 R-BTA-73618 https://reactome.org/PathwayBrowser/#/R-BTA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Bos taurus 15377 R-BTA-73620 https://reactome.org/PathwayBrowser/#/R-BTA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Bos taurus 15377 R-BTA-73647 https://reactome.org/PathwayBrowser/#/R-BTA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Bos taurus 15377 R-BTA-73666 https://reactome.org/PathwayBrowser/#/R-BTA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Bos taurus 15377 R-BTA-73792 https://reactome.org/PathwayBrowser/#/R-BTA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Bos taurus 15377 R-BTA-73794 https://reactome.org/PathwayBrowser/#/R-BTA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Bos taurus 15377 R-BTA-73797 https://reactome.org/PathwayBrowser/#/R-BTA-73797 FAICAR => IMP + H2O IEA Bos taurus 15377 R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 15377 R-BTA-73815 https://reactome.org/PathwayBrowser/#/R-BTA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Bos taurus 15377 R-BTA-74059 https://reactome.org/PathwayBrowser/#/R-BTA-74059 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 15377 R-BTA-74241 https://reactome.org/PathwayBrowser/#/R-BTA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Bos taurus 15377 R-BTA-74247 https://reactome.org/PathwayBrowser/#/R-BTA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Bos taurus 15377 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 15377 R-BTA-74255 https://reactome.org/PathwayBrowser/#/R-BTA-74255 Guanine + H2O => Xanthine + NH4+ IEA Bos taurus 15377 R-BTA-74258 https://reactome.org/PathwayBrowser/#/R-BTA-74258 XDH oxidizes xanthine to form urate IEA Bos taurus 15377 R-BTA-74733 https://reactome.org/PathwayBrowser/#/R-BTA-74733 Insulin receptor de-phosphorylation IEA Bos taurus 15377 R-BTA-74948 https://reactome.org/PathwayBrowser/#/R-BTA-74948 PP2A dephosphorylates p-RHO to RHO IEA Bos taurus 15377 R-BTA-75872 https://reactome.org/PathwayBrowser/#/R-BTA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Bos taurus 15377 R-BTA-75899 https://reactome.org/PathwayBrowser/#/R-BTA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Bos taurus 15377 R-BTA-76031 https://reactome.org/PathwayBrowser/#/R-BTA-76031 2 H2O2 => O2 + 2 H2O IEA Bos taurus 15377 R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 15377 R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 15377 R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 15377 R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 15377 R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 15377 R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 15377 R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 15377 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 15377 R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 15377 R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 15377 R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 15377 R-BTA-76590 https://reactome.org/PathwayBrowser/#/R-BTA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Bos taurus 15377 R-BTA-77256 https://reactome.org/PathwayBrowser/#/R-BTA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Bos taurus 15377 R-BTA-77277 https://reactome.org/PathwayBrowser/#/R-BTA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Bos taurus 15377 R-BTA-77301 https://reactome.org/PathwayBrowser/#/R-BTA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Bos taurus 15377 R-BTA-77314 https://reactome.org/PathwayBrowser/#/R-BTA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Bos taurus 15377 R-BTA-77325 https://reactome.org/PathwayBrowser/#/R-BTA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Bos taurus 15377 R-BTA-77333 https://reactome.org/PathwayBrowser/#/R-BTA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Bos taurus 15377 R-BTA-77344 https://reactome.org/PathwayBrowser/#/R-BTA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Bos taurus 15377 R-BTA-77614 https://reactome.org/PathwayBrowser/#/R-BTA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Bos taurus 15377 R-BTA-77615 https://reactome.org/PathwayBrowser/#/R-BTA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Bos taurus 15377 R-BTA-83677 https://reactome.org/PathwayBrowser/#/R-BTA-83677 C4 deamination of cytidine IEA Bos taurus 15377 R-BTA-870437 https://reactome.org/PathwayBrowser/#/R-BTA-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Bos taurus 15377 R-BTA-8847579 https://reactome.org/PathwayBrowser/#/R-BTA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Bos taurus 15377 R-BTA-8848053 https://reactome.org/PathwayBrowser/#/R-BTA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Bos taurus 15377 R-BTA-8848215 https://reactome.org/PathwayBrowser/#/R-BTA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Bos taurus 15377 R-BTA-8848338 https://reactome.org/PathwayBrowser/#/R-BTA-8848338 PNPLA4 hydrolyzes TAG IEA Bos taurus 15377 R-BTA-8848355 https://reactome.org/PathwayBrowser/#/R-BTA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Bos taurus 15377 R-BTA-8848484 https://reactome.org/PathwayBrowser/#/R-BTA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Bos taurus 15377 R-BTA-8849435 https://reactome.org/PathwayBrowser/#/R-BTA-8849435 PTPN1 dephosphorylates PTK6 IEA Bos taurus 15377 R-BTA-8849857 https://reactome.org/PathwayBrowser/#/R-BTA-8849857 KLK5 cleaves and activates CELA2 IEA Bos taurus 15377 R-BTA-8849969 https://reactome.org/PathwayBrowser/#/R-BTA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Bos taurus 15377 R-BTA-8850594 https://reactome.org/PathwayBrowser/#/R-BTA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Bos taurus 15377 R-BTA-8850831 https://reactome.org/PathwayBrowser/#/R-BTA-8850831 KLK5 cleaves and activates KLK8 IEA Bos taurus 15377 R-BTA-8850846 https://reactome.org/PathwayBrowser/#/R-BTA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-BTA-8850854 https://reactome.org/PathwayBrowser/#/R-BTA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-BTA-8851110 https://reactome.org/PathwayBrowser/#/R-BTA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-BTA-8851129 https://reactome.org/PathwayBrowser/#/R-BTA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-BTA-8852200 https://reactome.org/PathwayBrowser/#/R-BTA-8852200 Inactivation of LCK by PTPN22 IEA Bos taurus 15377 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 15377 R-BTA-8853686 https://reactome.org/PathwayBrowser/#/R-BTA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Bos taurus 15377 R-BTA-8854173 https://reactome.org/PathwayBrowser/#/R-BTA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Bos taurus 15377 R-BTA-8854255 https://reactome.org/PathwayBrowser/#/R-BTA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Bos taurus 15377 R-BTA-8854329 https://reactome.org/PathwayBrowser/#/R-BTA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Bos taurus 15377 R-BTA-8854604 https://reactome.org/PathwayBrowser/#/R-BTA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Bos taurus 15377 R-BTA-8854612 https://reactome.org/PathwayBrowser/#/R-BTA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Bos taurus 15377 R-BTA-8855381 https://reactome.org/PathwayBrowser/#/R-BTA-8855381 PTPN22 dephosphorylates ZAP70 IEA Bos taurus 15377 R-BTA-8855490 https://reactome.org/PathwayBrowser/#/R-BTA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Bos taurus 15377 R-BTA-8855825 https://reactome.org/PathwayBrowser/#/R-BTA-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Bos taurus 15377 R-BTA-8856951 https://reactome.org/PathwayBrowser/#/R-BTA-8856951 PP2A demethylation by PPME1 IEA Bos taurus 15377 R-BTA-8862184 https://reactome.org/PathwayBrowser/#/R-BTA-8862184 USP48 cleaves polyubiquitin IEA Bos taurus 15377 R-BTA-8862320 https://reactome.org/PathwayBrowser/#/R-BTA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Bos taurus 15377 R-BTA-8863804 https://reactome.org/PathwayBrowser/#/R-BTA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Bos taurus 15377 R-BTA-8864036 https://reactome.org/PathwayBrowser/#/R-BTA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Bos taurus 15377 R-BTA-8864125 https://reactome.org/PathwayBrowser/#/R-BTA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Bos taurus 15377 R-BTA-8865667 https://reactome.org/PathwayBrowser/#/R-BTA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Bos taurus 15377 R-BTA-8866405 https://reactome.org/PathwayBrowser/#/R-BTA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 15377 R-BTA-8866542 https://reactome.org/PathwayBrowser/#/R-BTA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Bos taurus 15377 R-BTA-8866601 https://reactome.org/PathwayBrowser/#/R-BTA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Bos taurus 15377 R-BTA-8867047 https://reactome.org/PathwayBrowser/#/R-BTA-8867047 PTPN3 dephosphorylates EPS15 IEA Bos taurus 15377 R-BTA-8867344 https://reactome.org/PathwayBrowser/#/R-BTA-8867344 OMA1 hydrolyses OPA1 IEA Bos taurus 15377 R-BTA-8867658 https://reactome.org/PathwayBrowser/#/R-BTA-8867658 PTPN3 dephosphorylates MAPK12 IEA Bos taurus 15377 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 15377 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 15377 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 15377 R-BTA-8869206 https://reactome.org/PathwayBrowser/#/R-BTA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Bos taurus 15377 R-BTA-8869456 https://reactome.org/PathwayBrowser/#/R-BTA-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Bos taurus 15377 R-BTA-8869506 https://reactome.org/PathwayBrowser/#/R-BTA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Bos taurus 15377 R-BTA-8870346 https://reactome.org/PathwayBrowser/#/R-BTA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Bos taurus 15377 R-BTA-8874435 https://reactome.org/PathwayBrowser/#/R-BTA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Bos taurus 15377 R-BTA-8875443 https://reactome.org/PathwayBrowser/#/R-BTA-8875443 USP8 deubiquitinates LRIG1 IEA Bos taurus 15377 R-BTA-8878581 https://reactome.org/PathwayBrowser/#/R-BTA-8878581 TYRP1 oxidises DHICA to IQCA IEA Bos taurus 15377 R-BTA-8878654 https://reactome.org/PathwayBrowser/#/R-BTA-8878654 ACP6 hydrolyses MYS-LPA IEA Bos taurus 15377 R-BTA-8878787 https://reactome.org/PathwayBrowser/#/R-BTA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Bos taurus 15377 R-BTA-888548 https://reactome.org/PathwayBrowser/#/R-BTA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Bos taurus 15377 R-BTA-8932633 https://reactome.org/PathwayBrowser/#/R-BTA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Bos taurus 15377 R-BTA-8933328 https://reactome.org/PathwayBrowser/#/R-BTA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Bos taurus 15377 R-BTA-8933635 https://reactome.org/PathwayBrowser/#/R-BTA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Bos taurus 15377 R-BTA-8936442 https://reactome.org/PathwayBrowser/#/R-BTA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Bos taurus 15377 R-BTA-8937442 https://reactome.org/PathwayBrowser/#/R-BTA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Bos taurus 15377 R-BTA-8937767 https://reactome.org/PathwayBrowser/#/R-BTA-8937767 PTPN11 dephosphorylates RUNX1 IEA Bos taurus 15377 R-BTA-8938076 https://reactome.org/PathwayBrowser/#/R-BTA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Bos taurus 15377 R-BTA-8940070 https://reactome.org/PathwayBrowser/#/R-BTA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Bos taurus 15377 R-BTA-8940074 https://reactome.org/PathwayBrowser/#/R-BTA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Bos taurus 15377 R-BTA-8940388 https://reactome.org/PathwayBrowser/#/R-BTA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Bos taurus 15377 R-BTA-8943279 https://reactome.org/PathwayBrowser/#/R-BTA-8943279 GGT dimers hydrolyse GSH IEA Bos taurus 15377 R-BTA-8952137 https://reactome.org/PathwayBrowser/#/R-BTA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Bos taurus 15377 R-BTA-8952251 https://reactome.org/PathwayBrowser/#/R-BTA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Bos taurus 15377 R-BTA-8952903 https://reactome.org/PathwayBrowser/#/R-BTA-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Bos taurus 15377 R-BTA-8953339 https://reactome.org/PathwayBrowser/#/R-BTA-8953339 DNPH1 hydrolyses dGMP IEA Bos taurus 15377 R-BTA-8953499 https://reactome.org/PathwayBrowser/#/R-BTA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Bos taurus 15377 R-BTA-8954398 https://reactome.org/PathwayBrowser/#/R-BTA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Bos taurus 15377 R-BTA-8955817 https://reactome.org/PathwayBrowser/#/R-BTA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Bos taurus 15377 R-BTA-8979996 https://reactome.org/PathwayBrowser/#/R-BTA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Bos taurus 15377 R-BTA-8980228 https://reactome.org/PathwayBrowser/#/R-BTA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Bos taurus 15377 R-BTA-8981637 https://reactome.org/PathwayBrowser/#/R-BTA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Bos taurus 15377 R-BTA-8985594 https://reactome.org/PathwayBrowser/#/R-BTA-8985594 MYO9B inactivates RHOA IEA Bos taurus 15377 R-BTA-8986083 https://reactome.org/PathwayBrowser/#/R-BTA-8986083 USP33 deubiquitinates ROBO1 IEA Bos taurus 15377 R-BTA-9008822 https://reactome.org/PathwayBrowser/#/R-BTA-9008822 PPM1D dephosphorylates RUNX2 IEA Bos taurus 15377 R-BTA-9009950 https://reactome.org/PathwayBrowser/#/R-BTA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Bos taurus 15377 R-BTA-9013111 https://reactome.org/PathwayBrowser/#/R-BTA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Bos taurus 15377 R-BTA-9013144 https://reactome.org/PathwayBrowser/#/R-BTA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Bos taurus 15377 R-BTA-9013161 https://reactome.org/PathwayBrowser/#/R-BTA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Bos taurus 15377 R-BTA-9013437 https://reactome.org/PathwayBrowser/#/R-BTA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Bos taurus 15377 R-BTA-9014295 https://reactome.org/PathwayBrowser/#/R-BTA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Bos taurus 15377 R-BTA-9014434 https://reactome.org/PathwayBrowser/#/R-BTA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Bos taurus 15377 R-BTA-9014627 https://reactome.org/PathwayBrowser/#/R-BTA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Bos taurus 15377 R-BTA-9014741 https://reactome.org/PathwayBrowser/#/R-BTA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Bos taurus 15377 R-BTA-9017488 https://reactome.org/PathwayBrowser/#/R-BTA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Bos taurus 15377 R-BTA-9018745 https://reactome.org/PathwayBrowser/#/R-BTA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Bos taurus 15377 R-BTA-9018806 https://reactome.org/PathwayBrowser/#/R-BTA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Bos taurus 15377 R-BTA-9018814 https://reactome.org/PathwayBrowser/#/R-BTA-9018814 RHOT1 hydrolyzes GTP IEA Bos taurus 15377 R-BTA-9018826 https://reactome.org/PathwayBrowser/#/R-BTA-9018826 RHOT2 hydrolyzes GTP IEA Bos taurus 15377 R-BTA-9018862 https://reactome.org/PathwayBrowser/#/R-BTA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Bos taurus 15377 R-BTA-9018868 https://reactome.org/PathwayBrowser/#/R-BTA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Bos taurus 15377 R-BTA-9018877 https://reactome.org/PathwayBrowser/#/R-BTA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Bos taurus 15377 R-BTA-9018895 https://reactome.org/PathwayBrowser/#/R-BTA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Bos taurus 15377 R-BTA-9020252 https://reactome.org/PathwayBrowser/#/R-BTA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Bos taurus 15377 R-BTA-9020253 https://reactome.org/PathwayBrowser/#/R-BTA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Bos taurus 15377 R-BTA-9020257 https://reactome.org/PathwayBrowser/#/R-BTA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Bos taurus 15377 R-BTA-9020258 https://reactome.org/PathwayBrowser/#/R-BTA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Bos taurus 15377 R-BTA-9020270 https://reactome.org/PathwayBrowser/#/R-BTA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Bos taurus 15377 R-BTA-9020271 https://reactome.org/PathwayBrowser/#/R-BTA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Bos taurus 15377 R-BTA-9020273 https://reactome.org/PathwayBrowser/#/R-BTA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Bos taurus 15377 R-BTA-9024890 https://reactome.org/PathwayBrowser/#/R-BTA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Bos taurus 15377 R-BTA-9027043 https://reactome.org/PathwayBrowser/#/R-BTA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Bos taurus 15377 R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 15377 R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 15377 R-BTA-9033491 https://reactome.org/PathwayBrowser/#/R-BTA-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Bos taurus 15377 R-BTA-9033520 https://reactome.org/PathwayBrowser/#/R-BTA-9033520 TYSND1 cleaves TYSND1 IEA Bos taurus 15377 R-BTA-9034539 https://reactome.org/PathwayBrowser/#/R-BTA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Bos taurus 15377 R-BTA-9036727 https://reactome.org/PathwayBrowser/#/R-BTA-9036727 GAA hydrolyzes lysosomal glycogen IEA Bos taurus 15377 R-BTA-9037761 https://reactome.org/PathwayBrowser/#/R-BTA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Bos taurus 15377 R-BTA-917841 https://reactome.org/PathwayBrowser/#/R-BTA-917841 Acidification of Tf:TfR1 containing endosome IEA Bos taurus 15377 R-BTA-917891 https://reactome.org/PathwayBrowser/#/R-BTA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Bos taurus 15377 R-BTA-917933 https://reactome.org/PathwayBrowser/#/R-BTA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Bos taurus 15377 R-BTA-917979 https://reactome.org/PathwayBrowser/#/R-BTA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Bos taurus 15377 R-BTA-936883 https://reactome.org/PathwayBrowser/#/R-BTA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Bos taurus 15377 R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 15377 R-BTA-937311 https://reactome.org/PathwayBrowser/#/R-BTA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Bos taurus 15377 R-BTA-939763 https://reactome.org/PathwayBrowser/#/R-BTA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Bos taurus 15377 R-BTA-947531 https://reactome.org/PathwayBrowser/#/R-BTA-947531 Molybdenum ion transfer onto molybdopterin IEA Bos taurus 15377 R-BTA-947535 https://reactome.org/PathwayBrowser/#/R-BTA-947535 Cyclisation of GTP to precursor Z IEA Bos taurus 15377 R-BTA-947591 https://reactome.org/PathwayBrowser/#/R-BTA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Bos taurus 15377 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 15377 R-BTA-9620103 https://reactome.org/PathwayBrowser/#/R-BTA-9620103 ALDH2 transforms GTN to NO IEA Bos taurus 15377 R-BTA-9624893 https://reactome.org/PathwayBrowser/#/R-BTA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Bos taurus 15377 R-BTA-9629675 https://reactome.org/PathwayBrowser/#/R-BTA-9629675 PDE3A hydrolyses cAMP to AMP IEA Bos taurus 15377 R-BTA-9635739 https://reactome.org/PathwayBrowser/#/R-BTA-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Bos taurus 15377 R-BTA-9638075 https://reactome.org/PathwayBrowser/#/R-BTA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Bos taurus 15377 R-BTA-9638076 https://reactome.org/PathwayBrowser/#/R-BTA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Bos taurus 15377 R-BTA-9638078 https://reactome.org/PathwayBrowser/#/R-BTA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Bos taurus 15377 R-BTA-9638120 https://reactome.org/PathwayBrowser/#/R-BTA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 15377 R-BTA-9644869 https://reactome.org/PathwayBrowser/#/R-BTA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Bos taurus 15377 R-BTA-9647994 https://reactome.org/PathwayBrowser/#/R-BTA-9647994 RAS proteins are depalmitoylated IEA Bos taurus 15377 R-BTA-965067 https://reactome.org/PathwayBrowser/#/R-BTA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Bos taurus 15377 R-BTA-965079 https://reactome.org/PathwayBrowser/#/R-BTA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Bos taurus 15377 R-BTA-9653514 https://reactome.org/PathwayBrowser/#/R-BTA-9653514 USP17L2 deubiquitinates RCE1 IEA Bos taurus 15377 R-BTA-9656891 https://reactome.org/PathwayBrowser/#/R-BTA-9656891 OPN1SW binds 11cRAL IEA Bos taurus 15377 R-BTA-9656893 https://reactome.org/PathwayBrowser/#/R-BTA-9656893 OPN1MW binds 11cRAL IEA Bos taurus 15377 R-BTA-9658445 https://reactome.org/PathwayBrowser/#/R-BTA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Bos taurus 15377 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 15377 R-BTA-9661417 https://reactome.org/PathwayBrowser/#/R-BTA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 15377 R-BTA-9667952 https://reactome.org/PathwayBrowser/#/R-BTA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Bos taurus 15377 R-BTA-9668419 https://reactome.org/PathwayBrowser/#/R-BTA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Bos taurus 15377 R-BTA-9673053 https://reactome.org/PathwayBrowser/#/R-BTA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Bos taurus 15377 R-BTA-9673054 https://reactome.org/PathwayBrowser/#/R-BTA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Bos taurus 15377 R-BTA-9674127 https://reactome.org/PathwayBrowser/#/R-BTA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Bos taurus 15377 R-BTA-9686524 https://reactome.org/PathwayBrowser/#/R-BTA-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Bos taurus 15377 R-BTA-9693282 https://reactome.org/PathwayBrowser/#/R-BTA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Bos taurus 15377 R-BTA-9698408 https://reactome.org/PathwayBrowser/#/R-BTA-9698408 PTPRJ dephosphorylates active FLT3 IEA Bos taurus 15377 R-BTA-9700200 https://reactome.org/PathwayBrowser/#/R-BTA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Bos taurus 15377 R-BTA-9701507 https://reactome.org/PathwayBrowser/#/R-BTA-9701507 PTPN6 dephosphorylates JAK3 IEA Bos taurus 15377 R-BTA-9701565 https://reactome.org/PathwayBrowser/#/R-BTA-9701565 HDACs deacetylate p-STAT3 dimers IEA Bos taurus 15377 R-BTA-9705507 https://reactome.org/PathwayBrowser/#/R-BTA-9705507 PDE3B hydrolyses cAMP to AMP IEA Bos taurus 15377 R-BTA-9706399 https://reactome.org/PathwayBrowser/#/R-BTA-9706399 RHOBTB3 hydrolyzes ATP IEA Bos taurus 15377 R-BTA-9708261 https://reactome.org/PathwayBrowser/#/R-BTA-9708261 PDE4A hydrolyses cAMP to AMP IEA Bos taurus 15377 R-BTA-9709360 https://reactome.org/PathwayBrowser/#/R-BTA-9709360 H2O2 reduces MetHb IEA Bos taurus 15377 R-BTA-9727198 https://reactome.org/PathwayBrowser/#/R-BTA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Bos taurus 15377 R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 15377 R-BTA-9727349 https://reactome.org/PathwayBrowser/#/R-BTA-9727349 XDH dehydrogenates xanthine to form urate IEA Bos taurus 15377 R-BTA-9727567 https://reactome.org/PathwayBrowser/#/R-BTA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Bos taurus 15377 R-BTA-9731228 https://reactome.org/PathwayBrowser/#/R-BTA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Bos taurus 15377 R-BTA-9731590 https://reactome.org/PathwayBrowser/#/R-BTA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Bos taurus 15377 R-BTA-9731613 https://reactome.org/PathwayBrowser/#/R-BTA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Bos taurus 15377 R-BTA-9731632 https://reactome.org/PathwayBrowser/#/R-BTA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Bos taurus 15377 R-BTA-9731661 https://reactome.org/PathwayBrowser/#/R-BTA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Bos taurus 15377 R-BTA-9748945 https://reactome.org/PathwayBrowser/#/R-BTA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Bos taurus 15377 R-BTA-9748957 https://reactome.org/PathwayBrowser/#/R-BTA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Bos taurus 15377 R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 15377 R-BTA-9749609 https://reactome.org/PathwayBrowser/#/R-BTA-9749609 BCHE hydrolyzes ASA- IEA Bos taurus 15377 R-BTA-9749647 https://reactome.org/PathwayBrowser/#/R-BTA-9749647 CES2 hydrolyzes ASA- IEA Bos taurus 15377 R-BTA-9749792 https://reactome.org/PathwayBrowser/#/R-BTA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Bos taurus 15377 R-BTA-9749986 https://reactome.org/PathwayBrowser/#/R-BTA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Bos taurus 15377 R-BTA-9750016 https://reactome.org/PathwayBrowser/#/R-BTA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Bos taurus 15377 R-BTA-9750546 https://reactome.org/PathwayBrowser/#/R-BTA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 15377 R-BTA-9750555 https://reactome.org/PathwayBrowser/#/R-BTA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Bos taurus 15377 R-BTA-9750617 https://reactome.org/PathwayBrowser/#/R-BTA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 15377 R-BTA-9750656 https://reactome.org/PathwayBrowser/#/R-BTA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Bos taurus 15377 R-BTA-9750942 https://reactome.org/PathwayBrowser/#/R-BTA-9750942 USP14 deubiquitinates NLRC5 IEA Bos taurus 15377 R-BTA-9753278 https://reactome.org/PathwayBrowser/#/R-BTA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 15377 R-BTA-9753280 https://reactome.org/PathwayBrowser/#/R-BTA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Bos taurus 15377 R-BTA-9753283 https://reactome.org/PathwayBrowser/#/R-BTA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 15377 R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 15377 R-BTA-9753285 https://reactome.org/PathwayBrowser/#/R-BTA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Bos taurus 15377 R-BTA-9753632 https://reactome.org/PathwayBrowser/#/R-BTA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Bos taurus 15377 R-BTA-9753634 https://reactome.org/PathwayBrowser/#/R-BTA-9753634 GGT dimers hydrolyse APAP-SG IEA Bos taurus 15377 R-BTA-9753944 https://reactome.org/PathwayBrowser/#/R-BTA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Bos taurus 15377 R-BTA-9754964 https://reactome.org/PathwayBrowser/#/R-BTA-9754964 ADA deamidates RBV IEA Bos taurus 15377 R-BTA-9755030 https://reactome.org/PathwayBrowser/#/R-BTA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Bos taurus 15377 R-BTA-9755078 https://reactome.org/PathwayBrowser/#/R-BTA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Bos taurus 15377 R-BTA-975593 https://reactome.org/PathwayBrowser/#/R-BTA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Bos taurus 15377 R-BTA-975594 https://reactome.org/PathwayBrowser/#/R-BTA-975594 PLB1 hydrolyses RPALM to atROL IEA Bos taurus 15377 R-BTA-9756138 https://reactome.org/PathwayBrowser/#/R-BTA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Bos taurus 15377 R-BTA-9756162 https://reactome.org/PathwayBrowser/#/R-BTA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Bos taurus 15377 R-BTA-9756169 https://reactome.org/PathwayBrowser/#/R-BTA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Bos taurus 15377 R-BTA-9756177 https://reactome.org/PathwayBrowser/#/R-BTA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Bos taurus 15377 R-BTA-9756180 https://reactome.org/PathwayBrowser/#/R-BTA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Bos taurus 15377 R-BTA-9758674 https://reactome.org/PathwayBrowser/#/R-BTA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Bos taurus 15377 R-BTA-9759206 https://reactome.org/PathwayBrowser/#/R-BTA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Bos taurus 15377 R-BTA-9759454 https://reactome.org/PathwayBrowser/#/R-BTA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Bos taurus 15377 R-BTA-9759461 https://reactome.org/PathwayBrowser/#/R-BTA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Bos taurus 15377 R-BTA-977324 https://reactome.org/PathwayBrowser/#/R-BTA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Bos taurus 15377 R-BTA-9794120 https://reactome.org/PathwayBrowser/#/R-BTA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Bos taurus 15377 R-BTA-9794572 https://reactome.org/PathwayBrowser/#/R-BTA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Bos taurus 15377 R-BTA-983144 https://reactome.org/PathwayBrowser/#/R-BTA-983144 Transport of Antigen peptide in to ER IEA Bos taurus 15377 R-BTA-983422 https://reactome.org/PathwayBrowser/#/R-BTA-983422 Disassembly of COPII coated vesicle IEA Bos taurus 15377 R-BTA-9837419 https://reactome.org/PathwayBrowser/#/R-BTA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Bos taurus 15377 R-BTA-9838004 https://reactome.org/PathwayBrowser/#/R-BTA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Bos taurus 15377 R-BTA-9838081 https://reactome.org/PathwayBrowser/#/R-BTA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Bos taurus 15377 R-BTA-9838289 https://reactome.org/PathwayBrowser/#/R-BTA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Bos taurus 15377 R-BTA-9839059 https://reactome.org/PathwayBrowser/#/R-BTA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Bos taurus 15377 R-BTA-9839072 https://reactome.org/PathwayBrowser/#/R-BTA-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Bos taurus 15377 R-BTA-9839105 https://reactome.org/PathwayBrowser/#/R-BTA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Bos taurus 15377 R-BTA-9839110 https://reactome.org/PathwayBrowser/#/R-BTA-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Bos taurus 15377 R-BTA-9839113 https://reactome.org/PathwayBrowser/#/R-BTA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Bos taurus 15377 R-BTA-9840408 https://reactome.org/PathwayBrowser/#/R-BTA-9840408 OMA1 cleaves DELE1 IEA Bos taurus 15377 R-BTA-9840795 https://reactome.org/PathwayBrowser/#/R-BTA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Bos taurus 15377 R-BTA-9840833 https://reactome.org/PathwayBrowser/#/R-BTA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Bos taurus 15377 R-BTA-9840884 https://reactome.org/PathwayBrowser/#/R-BTA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Bos taurus 15377 R-BTA-9840949 https://reactome.org/PathwayBrowser/#/R-BTA-9840949 ARSA removes sulfate from SM3 IEA Bos taurus 15377 R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 15377 R-BTA-9843721 https://reactome.org/PathwayBrowser/#/R-BTA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Bos taurus 15377 R-BTA-9853385 https://reactome.org/PathwayBrowser/#/R-BTA-9853385 PPP1CC dephosphorylates PLK1 IEA Bos taurus 15377 R-BTA-9861626 https://reactome.org/PathwayBrowser/#/R-BTA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Bos taurus 15377 R-BTA-9861725 https://reactome.org/PathwayBrowser/#/R-BTA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Bos taurus 15377 R-BTA-997309 https://reactome.org/PathwayBrowser/#/R-BTA-997309 Dephosphorylation of STAT1 by SHP2 IEA Bos taurus 15377 R-BTA-997311 https://reactome.org/PathwayBrowser/#/R-BTA-997311 Dephosphorylation of TYK2 by PTP1B IEA Bos taurus 15377 R-BTA-997314 https://reactome.org/PathwayBrowser/#/R-BTA-997314 Dephosphorylation of JAK1 by SHP1 IEA Bos taurus 15377 R-BTA-997326 https://reactome.org/PathwayBrowser/#/R-BTA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Bos taurus 15377 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 15377 R-CEL-111742 https://reactome.org/PathwayBrowser/#/R-CEL-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 15377 R-CEL-111751 https://reactome.org/PathwayBrowser/#/R-CEL-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 15377 R-CEL-111804 https://reactome.org/PathwayBrowser/#/R-CEL-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 15377 R-CEL-111879 https://reactome.org/PathwayBrowser/#/R-CEL-111879 PIP2 hydrolysis IEA Caenorhabditis elegans 15377 R-CEL-111955 https://reactome.org/PathwayBrowser/#/R-CEL-111955 cAMP hydrolysis by Cam-PDE 1 IEA Caenorhabditis elegans 15377 R-CEL-111962 https://reactome.org/PathwayBrowser/#/R-CEL-111962 PDE4A,C,D hydrolyse cAMP IEA Caenorhabditis elegans 15377 R-CEL-112037 https://reactome.org/PathwayBrowser/#/R-CEL-112037 Inactivation of PLC beta IEA Caenorhabditis elegans 15377 R-CEL-1237045 https://reactome.org/PathwayBrowser/#/R-CEL-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Caenorhabditis elegans 15377 R-CEL-1237047 https://reactome.org/PathwayBrowser/#/R-CEL-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Caenorhabditis elegans 15377 R-CEL-1237059 https://reactome.org/PathwayBrowser/#/R-CEL-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Caenorhabditis elegans 15377 R-CEL-1237081 https://reactome.org/PathwayBrowser/#/R-CEL-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Caenorhabditis elegans 15377 R-CEL-1237129 https://reactome.org/PathwayBrowser/#/R-CEL-1237129 Acireductone is created IEA Caenorhabditis elegans 15377 R-CEL-1247910 https://reactome.org/PathwayBrowser/#/R-CEL-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Caenorhabditis elegans 15377 R-CEL-1247935 https://reactome.org/PathwayBrowser/#/R-CEL-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Caenorhabditis elegans 15377 R-CEL-1363274 https://reactome.org/PathwayBrowser/#/R-CEL-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Caenorhabditis elegans 15377 R-CEL-1363276 https://reactome.org/PathwayBrowser/#/R-CEL-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Caenorhabditis elegans 15377 R-CEL-1369065 https://reactome.org/PathwayBrowser/#/R-CEL-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Caenorhabditis elegans 15377 R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 15377 R-CEL-141348 https://reactome.org/PathwayBrowser/#/R-CEL-141348 PAO:FAD oxidises NASPM to PTCN IEA Caenorhabditis elegans 15377 R-CEL-141351 https://reactome.org/PathwayBrowser/#/R-CEL-141351 PAOX:FAD oxidises NASPN to SPM IEA Caenorhabditis elegans 15377 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 15377 R-CEL-1454916 https://reactome.org/PathwayBrowser/#/R-CEL-1454916 The ABCC family mediates organic anion transport IEA Caenorhabditis elegans 15377 R-CEL-1467466 https://reactome.org/PathwayBrowser/#/R-CEL-1467466 ABCA4 mediates atRAL transport IEA Caenorhabditis elegans 15377 R-CEL-1474146 https://reactome.org/PathwayBrowser/#/R-CEL-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Caenorhabditis elegans 15377 R-CEL-1475017 https://reactome.org/PathwayBrowser/#/R-CEL-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Caenorhabditis elegans 15377 R-CEL-1475022 https://reactome.org/PathwayBrowser/#/R-CEL-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Caenorhabditis elegans 15377 R-CEL-1475025 https://reactome.org/PathwayBrowser/#/R-CEL-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Caenorhabditis elegans 15377 R-CEL-1475026 https://reactome.org/PathwayBrowser/#/R-CEL-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Caenorhabditis elegans 15377 R-CEL-1475028 https://reactome.org/PathwayBrowser/#/R-CEL-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Caenorhabditis elegans 15377 R-CEL-1475032 https://reactome.org/PathwayBrowser/#/R-CEL-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Caenorhabditis elegans 15377 R-CEL-1475435 https://reactome.org/PathwayBrowser/#/R-CEL-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Caenorhabditis elegans 15377 R-CEL-1475436 https://reactome.org/PathwayBrowser/#/R-CEL-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Caenorhabditis elegans 15377 R-CEL-1482604 https://reactome.org/PathwayBrowser/#/R-CEL-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Caenorhabditis elegans 15377 R-CEL-1482656 https://reactome.org/PathwayBrowser/#/R-CEL-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Caenorhabditis elegans 15377 R-CEL-1482679 https://reactome.org/PathwayBrowser/#/R-CEL-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Caenorhabditis elegans 15377 R-CEL-1482776 https://reactome.org/PathwayBrowser/#/R-CEL-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Caenorhabditis elegans 15377 R-CEL-1482777 https://reactome.org/PathwayBrowser/#/R-CEL-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Caenorhabditis elegans 15377 R-CEL-1482811 https://reactome.org/PathwayBrowser/#/R-CEL-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Caenorhabditis elegans 15377 R-CEL-1482816 https://reactome.org/PathwayBrowser/#/R-CEL-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Caenorhabditis elegans 15377 R-CEL-1482856 https://reactome.org/PathwayBrowser/#/R-CEL-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Caenorhabditis elegans 15377 R-CEL-1482868 https://reactome.org/PathwayBrowser/#/R-CEL-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Caenorhabditis elegans 15377 R-CEL-1482884 https://reactome.org/PathwayBrowser/#/R-CEL-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Caenorhabditis elegans 15377 R-CEL-1482887 https://reactome.org/PathwayBrowser/#/R-CEL-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Caenorhabditis elegans 15377 R-CEL-1482900 https://reactome.org/PathwayBrowser/#/R-CEL-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Caenorhabditis elegans 15377 R-CEL-1482907 https://reactome.org/PathwayBrowser/#/R-CEL-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Caenorhabditis elegans 15377 R-CEL-1483182 https://reactome.org/PathwayBrowser/#/R-CEL-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Caenorhabditis elegans 15377 R-CEL-1483203 https://reactome.org/PathwayBrowser/#/R-CEL-1483203 PA is dephosphorylated to DAG by LPIN IEA Caenorhabditis elegans 15377 R-CEL-156526 https://reactome.org/PathwayBrowser/#/R-CEL-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Caenorhabditis elegans 15377 R-CEL-159425 https://reactome.org/PathwayBrowser/#/R-CEL-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 15377 R-CEL-1602368 https://reactome.org/PathwayBrowser/#/R-CEL-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Caenorhabditis elegans 15377 R-CEL-1602374 https://reactome.org/PathwayBrowser/#/R-CEL-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Caenorhabditis elegans 15377 R-CEL-1602377 https://reactome.org/PathwayBrowser/#/R-CEL-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Caenorhabditis elegans 15377 R-CEL-1602398 https://reactome.org/PathwayBrowser/#/R-CEL-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Caenorhabditis elegans 15377 R-CEL-1602399 https://reactome.org/PathwayBrowser/#/R-CEL-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Caenorhabditis elegans 15377 R-CEL-1602417 https://reactome.org/PathwayBrowser/#/R-CEL-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Caenorhabditis elegans 15377 R-CEL-1602446 https://reactome.org/PathwayBrowser/#/R-CEL-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Caenorhabditis elegans 15377 R-CEL-1605591 https://reactome.org/PathwayBrowser/#/R-CEL-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Caenorhabditis elegans 15377 R-CEL-1605595 https://reactome.org/PathwayBrowser/#/R-CEL-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Caenorhabditis elegans 15377 R-CEL-1605624 https://reactome.org/PathwayBrowser/#/R-CEL-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Caenorhabditis elegans 15377 R-CEL-1605632 https://reactome.org/PathwayBrowser/#/R-CEL-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Caenorhabditis elegans 15377 R-CEL-1605736 https://reactome.org/PathwayBrowser/#/R-CEL-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Caenorhabditis elegans 15377 R-CEL-1605797 https://reactome.org/PathwayBrowser/#/R-CEL-1605797 SMPD1 hydrolyzes SPHM IEA Caenorhabditis elegans 15377 R-CEL-1606273 https://reactome.org/PathwayBrowser/#/R-CEL-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Caenorhabditis elegans 15377 R-CEL-1606288 https://reactome.org/PathwayBrowser/#/R-CEL-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Caenorhabditis elegans 15377 R-CEL-1606312 https://reactome.org/PathwayBrowser/#/R-CEL-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Caenorhabditis elegans 15377 R-CEL-1606564 https://reactome.org/PathwayBrowser/#/R-CEL-1606564 GALC hydrolyzes GalCer IEA Caenorhabditis elegans 15377 R-CEL-1606602 https://reactome.org/PathwayBrowser/#/R-CEL-1606602 ASAH1 hydrolyzes ceramide IEA Caenorhabditis elegans 15377 R-CEL-1606789 https://reactome.org/PathwayBrowser/#/R-CEL-1606789 ARSB hydrolyses DS IEA Caenorhabditis elegans 15377 R-CEL-1614524 https://reactome.org/PathwayBrowser/#/R-CEL-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Caenorhabditis elegans 15377 R-CEL-1614544 https://reactome.org/PathwayBrowser/#/R-CEL-1614544 Sulfite is oxidized to sulfate IEA Caenorhabditis elegans 15377 R-CEL-1614583 https://reactome.org/PathwayBrowser/#/R-CEL-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Caenorhabditis elegans 15377 R-CEL-1614605 https://reactome.org/PathwayBrowser/#/R-CEL-1614605 Persulfide sulfur is dioxygenated IEA Caenorhabditis elegans 15377 R-CEL-1614614 https://reactome.org/PathwayBrowser/#/R-CEL-1614614 Cysteine is degraded to serine and H2S IEA Caenorhabditis elegans 15377 R-CEL-1614631 https://reactome.org/PathwayBrowser/#/R-CEL-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Caenorhabditis elegans 15377 R-CEL-162425 https://reactome.org/PathwayBrowser/#/R-CEL-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Caenorhabditis elegans 15377 R-CEL-162857 https://reactome.org/PathwayBrowser/#/R-CEL-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Caenorhabditis elegans 15377 R-CEL-1630306 https://reactome.org/PathwayBrowser/#/R-CEL-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Caenorhabditis elegans 15377 R-CEL-1638053 https://reactome.org/PathwayBrowser/#/R-CEL-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Caenorhabditis elegans 15377 R-CEL-1640164 https://reactome.org/PathwayBrowser/#/R-CEL-1640164 ENPP7 hydrolyzes sphingomyelin IEA Caenorhabditis elegans 15377 R-CEL-164832 https://reactome.org/PathwayBrowser/#/R-CEL-164832 ATPase synthesizes ATP IEA Caenorhabditis elegans 15377 R-CEL-1655453 https://reactome.org/PathwayBrowser/#/R-CEL-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Caenorhabditis elegans 15377 R-CEL-1675795 https://reactome.org/PathwayBrowser/#/R-CEL-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Caenorhabditis elegans 15377 R-CEL-1675824 https://reactome.org/PathwayBrowser/#/R-CEL-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Caenorhabditis elegans 15377 R-CEL-1675836 https://reactome.org/PathwayBrowser/#/R-CEL-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1675949 https://reactome.org/PathwayBrowser/#/R-CEL-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1675988 https://reactome.org/PathwayBrowser/#/R-CEL-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1675994 https://reactome.org/PathwayBrowser/#/R-CEL-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1676065 https://reactome.org/PathwayBrowser/#/R-CEL-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Caenorhabditis elegans 15377 R-CEL-1676105 https://reactome.org/PathwayBrowser/#/R-CEL-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Caenorhabditis elegans 15377 R-CEL-1676114 https://reactome.org/PathwayBrowser/#/R-CEL-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Caenorhabditis elegans 15377 R-CEL-1676124 https://reactome.org/PathwayBrowser/#/R-CEL-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Caenorhabditis elegans 15377 R-CEL-1676141 https://reactome.org/PathwayBrowser/#/R-CEL-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Caenorhabditis elegans 15377 R-CEL-1676149 https://reactome.org/PathwayBrowser/#/R-CEL-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1676162 https://reactome.org/PathwayBrowser/#/R-CEL-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Caenorhabditis elegans 15377 R-CEL-1676164 https://reactome.org/PathwayBrowser/#/R-CEL-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1676177 https://reactome.org/PathwayBrowser/#/R-CEL-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1676203 https://reactome.org/PathwayBrowser/#/R-CEL-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1678742 https://reactome.org/PathwayBrowser/#/R-CEL-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Caenorhabditis elegans 15377 R-CEL-1678854 https://reactome.org/PathwayBrowser/#/R-CEL-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Caenorhabditis elegans 15377 R-CEL-170153 https://reactome.org/PathwayBrowser/#/R-CEL-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Caenorhabditis elegans 15377 R-CEL-170158 https://reactome.org/PathwayBrowser/#/R-CEL-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Caenorhabditis elegans 15377 R-CEL-170161 https://reactome.org/PathwayBrowser/#/R-CEL-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Caenorhabditis elegans 15377 R-CEL-173597 https://reactome.org/PathwayBrowser/#/R-CEL-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Caenorhabditis elegans 15377 R-CEL-174110 https://reactome.org/PathwayBrowser/#/R-CEL-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Caenorhabditis elegans 15377 R-CEL-174401 https://reactome.org/PathwayBrowser/#/R-CEL-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Caenorhabditis elegans 15377 R-CEL-176606 https://reactome.org/PathwayBrowser/#/R-CEL-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Caenorhabditis elegans 15377 R-CEL-1793207 https://reactome.org/PathwayBrowser/#/R-CEL-1793207 ARSB hydrolyses C4S/C6S chains IEA Caenorhabditis elegans 15377 R-CEL-1793209 https://reactome.org/PathwayBrowser/#/R-CEL-1793209 HYAL1 hydrolyses Chondroitin chains IEA Caenorhabditis elegans 15377 R-CEL-1855154 https://reactome.org/PathwayBrowser/#/R-CEL-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-1855165 https://reactome.org/PathwayBrowser/#/R-CEL-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-1855166 https://reactome.org/PathwayBrowser/#/R-CEL-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-1855174 https://reactome.org/PathwayBrowser/#/R-CEL-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-1855177 https://reactome.org/PathwayBrowser/#/R-CEL-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1855180 https://reactome.org/PathwayBrowser/#/R-CEL-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-1855198 https://reactome.org/PathwayBrowser/#/R-CEL-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-1855202 https://reactome.org/PathwayBrowser/#/R-CEL-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-1855205 https://reactome.org/PathwayBrowser/#/R-CEL-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-1855210 https://reactome.org/PathwayBrowser/#/R-CEL-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-1855211 https://reactome.org/PathwayBrowser/#/R-CEL-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-1855213 https://reactome.org/PathwayBrowser/#/R-CEL-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1855214 https://reactome.org/PathwayBrowser/#/R-CEL-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Caenorhabditis elegans 15377 R-CEL-1855218 https://reactome.org/PathwayBrowser/#/R-CEL-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-1855221 https://reactome.org/PathwayBrowser/#/R-CEL-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1855222 https://reactome.org/PathwayBrowser/#/R-CEL-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-1861788 https://reactome.org/PathwayBrowser/#/R-CEL-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Caenorhabditis elegans 15377 R-CEL-1861789 https://reactome.org/PathwayBrowser/#/R-CEL-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Caenorhabditis elegans 15377 R-CEL-188979 https://reactome.org/PathwayBrowser/#/R-CEL-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Caenorhabditis elegans 15377 R-CEL-189053 https://reactome.org/PathwayBrowser/#/R-CEL-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Caenorhabditis elegans 15377 R-CEL-189062 https://reactome.org/PathwayBrowser/#/R-CEL-189062 lactose + H2O => D-glucose + D-galactose IEA Caenorhabditis elegans 15377 R-CEL-189069 https://reactome.org/PathwayBrowser/#/R-CEL-189069 sucrose + H2O => glucose + fructose IEA Caenorhabditis elegans 15377 R-CEL-189102 https://reactome.org/PathwayBrowser/#/R-CEL-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Caenorhabditis elegans 15377 R-CEL-191101 https://reactome.org/PathwayBrowser/#/R-CEL-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 15377 R-CEL-191108 https://reactome.org/PathwayBrowser/#/R-CEL-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 15377 R-CEL-191114 https://reactome.org/PathwayBrowser/#/R-CEL-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Caenorhabditis elegans 15377 R-CEL-191116 https://reactome.org/PathwayBrowser/#/R-CEL-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Caenorhabditis elegans 15377 R-CEL-191323 https://reactome.org/PathwayBrowser/#/R-CEL-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Caenorhabditis elegans 15377 R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 15377 R-CEL-192331 https://reactome.org/PathwayBrowser/#/R-CEL-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 15377 R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 15377 R-CEL-192430 https://reactome.org/PathwayBrowser/#/R-CEL-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 15377 R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 15377 R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 15377 R-CEL-193385 https://reactome.org/PathwayBrowser/#/R-CEL-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Caenorhabditis elegans 15377 R-CEL-193535 https://reactome.org/PathwayBrowser/#/R-CEL-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-193711 https://reactome.org/PathwayBrowser/#/R-CEL-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 15377 R-CEL-193727 https://reactome.org/PathwayBrowser/#/R-CEL-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 15377 R-CEL-193743 https://reactome.org/PathwayBrowser/#/R-CEL-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 15377 R-CEL-193766 https://reactome.org/PathwayBrowser/#/R-CEL-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 15377 R-CEL-196950 https://reactome.org/PathwayBrowser/#/R-CEL-196950 2xTRAP hydrolyzes FMN to RIB IEA Caenorhabditis elegans 15377 R-CEL-196955 https://reactome.org/PathwayBrowser/#/R-CEL-196955 2xENPP1 hydrolyzes FAD to FMN IEA Caenorhabditis elegans 15377 R-CEL-197271 https://reactome.org/PathwayBrowser/#/R-CEL-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Caenorhabditis elegans 15377 R-CEL-199456 https://reactome.org/PathwayBrowser/#/R-CEL-199456 PTEN dephosphorylates PIP3 IEA Caenorhabditis elegans 15377 R-CEL-199959 https://reactome.org/PathwayBrowser/#/R-CEL-199959 ERKs are inactivated by protein phosphatase 2A IEA Caenorhabditis elegans 15377 R-CEL-200661 https://reactome.org/PathwayBrowser/#/R-CEL-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Caenorhabditis elegans 15377 R-CEL-200740 https://reactome.org/PathwayBrowser/#/R-CEL-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Caenorhabditis elegans 15377 R-CEL-201035 https://reactome.org/PathwayBrowser/#/R-CEL-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Caenorhabditis elegans 15377 R-CEL-2022368 https://reactome.org/PathwayBrowser/#/R-CEL-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Caenorhabditis elegans 15377 R-CEL-2022381 https://reactome.org/PathwayBrowser/#/R-CEL-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 15377 R-CEL-2022396 https://reactome.org/PathwayBrowser/#/R-CEL-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Caenorhabditis elegans 15377 R-CEL-2022398 https://reactome.org/PathwayBrowser/#/R-CEL-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Caenorhabditis elegans 15377 R-CEL-2022399 https://reactome.org/PathwayBrowser/#/R-CEL-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Caenorhabditis elegans 15377 R-CEL-2022403 https://reactome.org/PathwayBrowser/#/R-CEL-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Caenorhabditis elegans 15377 R-CEL-2022405 https://reactome.org/PathwayBrowser/#/R-CEL-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 15377 R-CEL-2022412 https://reactome.org/PathwayBrowser/#/R-CEL-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Caenorhabditis elegans 15377 R-CEL-2022887 https://reactome.org/PathwayBrowser/#/R-CEL-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Caenorhabditis elegans 15377 R-CEL-2023971 https://reactome.org/PathwayBrowser/#/R-CEL-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-2023973 https://reactome.org/PathwayBrowser/#/R-CEL-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-2028294 https://reactome.org/PathwayBrowser/#/R-CEL-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Caenorhabditis elegans 15377 R-CEL-2029471 https://reactome.org/PathwayBrowser/#/R-CEL-2029471 Hydrolysis of PC to PA by PLD IEA Caenorhabditis elegans 15377 R-CEL-2029475 https://reactome.org/PathwayBrowser/#/R-CEL-2029475 Production of AA by iPLA2 upon FCGR activation IEA Caenorhabditis elegans 15377 R-CEL-203797 https://reactome.org/PathwayBrowser/#/R-CEL-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Caenorhabditis elegans 15377 R-CEL-204169 https://reactome.org/PathwayBrowser/#/R-CEL-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Caenorhabditis elegans 15377 R-CEL-2046084 https://reactome.org/PathwayBrowser/#/R-CEL-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-2046088 https://reactome.org/PathwayBrowser/#/R-CEL-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-2046089 https://reactome.org/PathwayBrowser/#/R-CEL-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-2046092 https://reactome.org/PathwayBrowser/#/R-CEL-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-2046094 https://reactome.org/PathwayBrowser/#/R-CEL-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-2046096 https://reactome.org/PathwayBrowser/#/R-CEL-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-2046097 https://reactome.org/PathwayBrowser/#/R-CEL-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-204662 https://reactome.org/PathwayBrowser/#/R-CEL-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Caenorhabditis elegans 15377 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 15377 R-CEL-2065357 https://reactome.org/PathwayBrowser/#/R-CEL-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Caenorhabditis elegans 15377 R-CEL-2066778 https://reactome.org/PathwayBrowser/#/R-CEL-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-2066779 https://reactome.org/PathwayBrowser/#/R-CEL-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Caenorhabditis elegans 15377 R-CEL-2090038 https://reactome.org/PathwayBrowser/#/R-CEL-2090038 NAGLU hydrolyses heparan chain(2) IEA Caenorhabditis elegans 15377 R-CEL-2090079 https://reactome.org/PathwayBrowser/#/R-CEL-2090079 GLB1 hydrolyses linker chain(2) IEA Caenorhabditis elegans 15377 R-CEL-209055 https://reactome.org/PathwayBrowser/#/R-CEL-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Caenorhabditis elegans 15377 R-CEL-209845 https://reactome.org/PathwayBrowser/#/R-CEL-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Caenorhabditis elegans 15377 R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 15377 R-CEL-2105001 https://reactome.org/PathwayBrowser/#/R-CEL-2105001 HEXA cleaves the terminal GalNAc from DS IEA Caenorhabditis elegans 15377 R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 15377 R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 15377 R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 15377 R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 15377 R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 15377 R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 15377 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 15377 R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 15377 R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 15377 R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 15377 R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 15377 R-CEL-2160874 https://reactome.org/PathwayBrowser/#/R-CEL-2160874 HYAL1 hydrolyses (HA)50 IEA Caenorhabditis elegans 15377 R-CEL-2161187 https://reactome.org/PathwayBrowser/#/R-CEL-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Caenorhabditis elegans 15377 R-CEL-2161195 https://reactome.org/PathwayBrowser/#/R-CEL-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Caenorhabditis elegans 15377 R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 15377 R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans 15377 R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Caenorhabditis elegans 15377 R-CEL-2161959 https://reactome.org/PathwayBrowser/#/R-CEL-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Caenorhabditis elegans 15377 R-CEL-2161999 https://reactome.org/PathwayBrowser/#/R-CEL-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Caenorhabditis elegans 15377 R-CEL-2162225 https://reactome.org/PathwayBrowser/#/R-CEL-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Caenorhabditis elegans 15377 R-CEL-2162226 https://reactome.org/PathwayBrowser/#/R-CEL-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Caenorhabditis elegans 15377 R-CEL-2162227 https://reactome.org/PathwayBrowser/#/R-CEL-2162227 GUSB tetramer hydrolyses (HA)2 IEA Caenorhabditis elegans 15377 R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 15377 R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 15377 R-CEL-2393939 https://reactome.org/PathwayBrowser/#/R-CEL-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 15377 R-CEL-2393954 https://reactome.org/PathwayBrowser/#/R-CEL-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 15377 R-CEL-2395873 https://reactome.org/PathwayBrowser/#/R-CEL-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Caenorhabditis elegans 15377 R-CEL-2395879 https://reactome.org/PathwayBrowser/#/R-CEL-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Caenorhabditis elegans 15377 R-CEL-2395965 https://reactome.org/PathwayBrowser/#/R-CEL-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Caenorhabditis elegans 15377 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 15377 R-CEL-2454118 https://reactome.org/PathwayBrowser/#/R-CEL-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Caenorhabditis elegans 15377 R-CEL-2465924 https://reactome.org/PathwayBrowser/#/R-CEL-2465924 OPN1LW binds 11cRAL IEA Caenorhabditis elegans 15377 R-CEL-2466085 https://reactome.org/PathwayBrowser/#/R-CEL-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Caenorhabditis elegans 15377 R-CEL-2509827 https://reactome.org/PathwayBrowser/#/R-CEL-2509827 ITPA hydrolyses ITP to IMP IEA Caenorhabditis elegans 15377 R-CEL-2509831 https://reactome.org/PathwayBrowser/#/R-CEL-2509831 ITPA hydrolyses XTP to XMP IEA Caenorhabditis elegans 15377 R-CEL-2509838 https://reactome.org/PathwayBrowser/#/R-CEL-2509838 ITPA hydrolyses dITP to dIMP IEA Caenorhabditis elegans 15377 R-CEL-2632521 https://reactome.org/PathwayBrowser/#/R-CEL-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Caenorhabditis elegans 15377 R-CEL-265783 https://reactome.org/PathwayBrowser/#/R-CEL-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-CEL-266046 https://reactome.org/PathwayBrowser/#/R-CEL-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Caenorhabditis elegans 15377 R-CEL-266072 https://reactome.org/PathwayBrowser/#/R-CEL-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Caenorhabditis elegans 15377 R-CEL-2995330 https://reactome.org/PathwayBrowser/#/R-CEL-2995330 COX10 transforms heme to heme O IEA Caenorhabditis elegans 15377 R-CEL-2995334 https://reactome.org/PathwayBrowser/#/R-CEL-2995334 COX15 transforms heme O to heme A IEA Caenorhabditis elegans 15377 R-CEL-2995388 https://reactome.org/PathwayBrowser/#/R-CEL-2995388 PP2A dephosphorylates BANF1 IEA Caenorhabditis elegans 15377 R-CEL-3002811 https://reactome.org/PathwayBrowser/#/R-CEL-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Caenorhabditis elegans 15377 R-CEL-3095901 https://reactome.org/PathwayBrowser/#/R-CEL-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Caenorhabditis elegans 15377 R-CEL-3204311 https://reactome.org/PathwayBrowser/#/R-CEL-3204311 AOX1 oxidises PXL to PDXate IEA Caenorhabditis elegans 15377 R-CEL-3322995 https://reactome.org/PathwayBrowser/#/R-CEL-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Caenorhabditis elegans 15377 R-CEL-3341343 https://reactome.org/PathwayBrowser/#/R-CEL-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Caenorhabditis elegans 15377 R-CEL-3341397 https://reactome.org/PathwayBrowser/#/R-CEL-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Caenorhabditis elegans 15377 R-CEL-3343700 https://reactome.org/PathwayBrowser/#/R-CEL-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Caenorhabditis elegans 15377 R-CEL-350901 https://reactome.org/PathwayBrowser/#/R-CEL-350901 Iodide is organified IEA Caenorhabditis elegans 15377 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 15377 R-CEL-3781011 https://reactome.org/PathwayBrowser/#/R-CEL-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Caenorhabditis elegans 15377 R-CEL-3781018 https://reactome.org/PathwayBrowser/#/R-CEL-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Caenorhabditis elegans 15377 R-CEL-380949 https://reactome.org/PathwayBrowser/#/R-CEL-380949 AMPK is dephosphorylated IEA Caenorhabditis elegans 15377 R-CEL-382560 https://reactome.org/PathwayBrowser/#/R-CEL-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Caenorhabditis elegans 15377 R-CEL-382575 https://reactome.org/PathwayBrowser/#/R-CEL-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Caenorhabditis elegans 15377 R-CEL-383190 https://reactome.org/PathwayBrowser/#/R-CEL-383190 HCO3- transport through ion channel IEA Caenorhabditis elegans 15377 R-CEL-389821 https://reactome.org/PathwayBrowser/#/R-CEL-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Caenorhabditis elegans 15377 R-CEL-389862 https://reactome.org/PathwayBrowser/#/R-CEL-389862 Conversion of glyoxylate to oxalate IEA Caenorhabditis elegans 15377 R-CEL-389986 https://reactome.org/PathwayBrowser/#/R-CEL-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-390252 https://reactome.org/PathwayBrowser/#/R-CEL-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-390304 https://reactome.org/PathwayBrowser/#/R-CEL-390304 acetyl-CoA + H2O => acetate + CoASH IEA Caenorhabditis elegans 15377 R-CEL-390329 https://reactome.org/PathwayBrowser/#/R-CEL-390329 Dephosphorylation of AKT by PP2A IEA Caenorhabditis elegans 15377 R-CEL-4093339 https://reactome.org/PathwayBrowser/#/R-CEL-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Caenorhabditis elegans 15377 R-CEL-416559 https://reactome.org/PathwayBrowser/#/R-CEL-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Caenorhabditis elegans 15377 R-CEL-418553 https://reactome.org/PathwayBrowser/#/R-CEL-418553 cAMP degradation by Phosphodiesterases IEA Caenorhabditis elegans 15377 R-CEL-428205 https://reactome.org/PathwayBrowser/#/R-CEL-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Caenorhabditis elegans 15377 R-CEL-428231 https://reactome.org/PathwayBrowser/#/R-CEL-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Caenorhabditis elegans 15377 R-CEL-428259 https://reactome.org/PathwayBrowser/#/R-CEL-428259 DEGS1 dehydrogenates dihydroceramide IEA Caenorhabditis elegans 15377 R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 15377 R-CEL-428690 https://reactome.org/PathwayBrowser/#/R-CEL-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Caenorhabditis elegans 15377 R-CEL-428696 https://reactome.org/PathwayBrowser/#/R-CEL-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Caenorhabditis elegans 15377 R-CEL-429157 https://reactome.org/PathwayBrowser/#/R-CEL-429157 ABCC4 accumulation of dense granule contents IEA Caenorhabditis elegans 15377 R-CEL-429860 https://reactome.org/PathwayBrowser/#/R-CEL-429860 DCP1-DCP2 complex decaps mRNA IEA Caenorhabditis elegans 15377 R-CEL-429961 https://reactome.org/PathwayBrowser/#/R-CEL-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Caenorhabditis elegans 15377 R-CEL-430028 https://reactome.org/PathwayBrowser/#/R-CEL-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Caenorhabditis elegans 15377 R-CEL-4419948 https://reactome.org/PathwayBrowser/#/R-CEL-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Caenorhabditis elegans 15377 R-CEL-445714 https://reactome.org/PathwayBrowser/#/R-CEL-445714 Aquaporin-3 passively transports water out of cell IEA Caenorhabditis elegans 15377 R-CEL-449937 https://reactome.org/PathwayBrowser/#/R-CEL-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Caenorhabditis elegans 15377 R-CEL-452036 https://reactome.org/PathwayBrowser/#/R-CEL-452036 arginine + H2O => ornithine + urea [ARG2] IEA Caenorhabditis elegans 15377 R-CEL-504054 https://reactome.org/PathwayBrowser/#/R-CEL-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Caenorhabditis elegans 15377 R-CEL-507868 https://reactome.org/PathwayBrowser/#/R-CEL-507868 Aquaporins passively transport water into cells IEA Caenorhabditis elegans 15377 R-CEL-507870 https://reactome.org/PathwayBrowser/#/R-CEL-507870 Aquaporins passively transport water out of cells IEA Caenorhabditis elegans 15377 R-CEL-508308 https://reactome.org/PathwayBrowser/#/R-CEL-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Caenorhabditis elegans 15377 R-CEL-5221130 https://reactome.org/PathwayBrowser/#/R-CEL-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Caenorhabditis elegans 15377 R-CEL-5223317 https://reactome.org/PathwayBrowser/#/R-CEL-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 15377 R-CEL-5251955 https://reactome.org/PathwayBrowser/#/R-CEL-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Caenorhabditis elegans 15377 R-CEL-5251959 https://reactome.org/PathwayBrowser/#/R-CEL-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Caenorhabditis elegans 15377 R-CEL-5251989 https://reactome.org/PathwayBrowser/#/R-CEL-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Caenorhabditis elegans 15377 R-CEL-5263614 https://reactome.org/PathwayBrowser/#/R-CEL-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Caenorhabditis elegans 15377 R-CEL-5263616 https://reactome.org/PathwayBrowser/#/R-CEL-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Caenorhabditis elegans 15377 R-CEL-5362522 https://reactome.org/PathwayBrowser/#/R-CEL-5362522 ALDHs oxidise atRAL to atRA IEA Caenorhabditis elegans 15377 R-CEL-5423647 https://reactome.org/PathwayBrowser/#/R-CEL-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Caenorhabditis elegans 15377 R-CEL-5433072 https://reactome.org/PathwayBrowser/#/R-CEL-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Caenorhabditis elegans 15377 R-CEL-5433074 https://reactome.org/PathwayBrowser/#/R-CEL-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Caenorhabditis elegans 15377 R-CEL-548843 https://reactome.org/PathwayBrowser/#/R-CEL-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Caenorhabditis elegans 15377 R-CEL-5631885 https://reactome.org/PathwayBrowser/#/R-CEL-5631885 PRDX1 overoxidizes IEA Caenorhabditis elegans 15377 R-CEL-5659861 https://reactome.org/PathwayBrowser/#/R-CEL-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 15377 R-CEL-5662692 https://reactome.org/PathwayBrowser/#/R-CEL-5662692 Dopa is oxidized to dopaquinone by TYR IEA Caenorhabditis elegans 15377 R-CEL-5672957 https://reactome.org/PathwayBrowser/#/R-CEL-5672957 PP2A dephosphorylates KSR1 IEA Caenorhabditis elegans 15377 R-CEL-5672961 https://reactome.org/PathwayBrowser/#/R-CEL-5672961 PP2A dephosphorylates inactive RAFs IEA Caenorhabditis elegans 15377 R-CEL-5675376 https://reactome.org/PathwayBrowser/#/R-CEL-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Caenorhabditis elegans 15377 R-CEL-5675431 https://reactome.org/PathwayBrowser/#/R-CEL-5675431 PP2A dephosphorylates RAF1 IEA Caenorhabditis elegans 15377 R-CEL-5675433 https://reactome.org/PathwayBrowser/#/R-CEL-5675433 PP5 dephosphorylates RAF1 S338 IEA Caenorhabditis elegans 15377 R-CEL-5676637 https://reactome.org/PathwayBrowser/#/R-CEL-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Caenorhabditis elegans 15377 R-CEL-5678327 https://reactome.org/PathwayBrowser/#/R-CEL-5678327 MIOX oxidises Ins to GlcA IEA Caenorhabditis elegans 15377 R-CEL-5678863 https://reactome.org/PathwayBrowser/#/R-CEL-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-CEL-5679041 https://reactome.org/PathwayBrowser/#/R-CEL-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-CEL-5682285 https://reactome.org/PathwayBrowser/#/R-CEL-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-CEL-5683714 https://reactome.org/PathwayBrowser/#/R-CEL-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Caenorhabditis elegans 15377 R-CEL-5684864 https://reactome.org/PathwayBrowser/#/R-CEL-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Caenorhabditis elegans 15377 R-CEL-5687464 https://reactome.org/PathwayBrowser/#/R-CEL-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Caenorhabditis elegans 15377 R-CEL-5687664 https://reactome.org/PathwayBrowser/#/R-CEL-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Caenorhabditis elegans 15377 R-CEL-5688797 https://reactome.org/PathwayBrowser/#/R-CEL-5688797 ATXN3 family cleave Ub chains IEA Caenorhabditis elegans 15377 R-CEL-5689000 https://reactome.org/PathwayBrowser/#/R-CEL-5689000 AADAC deacetylates PHEN IEA Caenorhabditis elegans 15377 R-CEL-5689950 https://reactome.org/PathwayBrowser/#/R-CEL-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Caenorhabditis elegans 15377 R-CEL-5690042 https://reactome.org/PathwayBrowser/#/R-CEL-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 15377 R-CEL-5690043 https://reactome.org/PathwayBrowser/#/R-CEL-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 15377 R-CEL-5690066 https://reactome.org/PathwayBrowser/#/R-CEL-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 15377 R-CEL-5690157 https://reactome.org/PathwayBrowser/#/R-CEL-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Caenorhabditis elegans 15377 R-CEL-5690159 https://reactome.org/PathwayBrowser/#/R-CEL-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Caenorhabditis elegans 15377 R-CEL-5690319 https://reactome.org/PathwayBrowser/#/R-CEL-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Caenorhabditis elegans 15377 R-CEL-5690517 https://reactome.org/PathwayBrowser/#/R-CEL-5690517 PPT1 hydrolyses palmitoylated proteins IEA Caenorhabditis elegans 15377 R-CEL-5690565 https://reactome.org/PathwayBrowser/#/R-CEL-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15377 R-CEL-5690808 https://reactome.org/PathwayBrowser/#/R-CEL-5690808 UCHL3, SENP8 cleave NEDD8 IEA Caenorhabditis elegans 15377 R-CEL-5691381 https://reactome.org/PathwayBrowser/#/R-CEL-5691381 MYSM1 deubiquitinates Histone H2A IEA Caenorhabditis elegans 15377 R-CEL-5691512 https://reactome.org/PathwayBrowser/#/R-CEL-5691512 APEH hydrolyses NAc-Ser-protein IEA Caenorhabditis elegans 15377 R-CEL-5692261 https://reactome.org/PathwayBrowser/#/R-CEL-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Caenorhabditis elegans 15377 R-CEL-5692283 https://reactome.org/PathwayBrowser/#/R-CEL-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Caenorhabditis elegans 15377 R-CEL-5692462 https://reactome.org/PathwayBrowser/#/R-CEL-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Caenorhabditis elegans 15377 R-CEL-5692754 https://reactome.org/PathwayBrowser/#/R-CEL-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Caenorhabditis elegans 15377 R-CEL-5693691 https://reactome.org/PathwayBrowser/#/R-CEL-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Caenorhabditis elegans 15377 R-CEL-5693724 https://reactome.org/PathwayBrowser/#/R-CEL-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Caenorhabditis elegans 15377 R-CEL-5693742 https://reactome.org/PathwayBrowser/#/R-CEL-5693742 FAAH hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 15377 R-CEL-5693751 https://reactome.org/PathwayBrowser/#/R-CEL-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 15377 R-CEL-5693761 https://reactome.org/PathwayBrowser/#/R-CEL-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Caenorhabditis elegans 15377 R-CEL-5693807 https://reactome.org/PathwayBrowser/#/R-CEL-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Caenorhabditis elegans 15377 R-CEL-5694077 https://reactome.org/PathwayBrowser/#/R-CEL-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Caenorhabditis elegans 15377 R-CEL-5694126 https://reactome.org/PathwayBrowser/#/R-CEL-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Caenorhabditis elegans 15377 R-CEL-5694462 https://reactome.org/PathwayBrowser/#/R-CEL-5694462 ABHD6,12 hydrolyse 3AG IEA Caenorhabditis elegans 15377 R-CEL-5694485 https://reactome.org/PathwayBrowser/#/R-CEL-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Caenorhabditis elegans 15377 R-CEL-5694583 https://reactome.org/PathwayBrowser/#/R-CEL-5694583 ABHD4 hydrolyses NAPE IEA Caenorhabditis elegans 15377 R-CEL-5695964 https://reactome.org/PathwayBrowser/#/R-CEL-5695964 ABHD14B hydrolyses PNPB IEA Caenorhabditis elegans 15377 R-CEL-5696080 https://reactome.org/PathwayBrowser/#/R-CEL-5696080 ALDH3B1 oxidises HXAL to PALM IEA Caenorhabditis elegans 15377 R-CEL-5696091 https://reactome.org/PathwayBrowser/#/R-CEL-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Caenorhabditis elegans 15377 R-CEL-5696101 https://reactome.org/PathwayBrowser/#/R-CEL-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Caenorhabditis elegans 15377 R-CEL-5696119 https://reactome.org/PathwayBrowser/#/R-CEL-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Caenorhabditis elegans 15377 R-CEL-5696197 https://reactome.org/PathwayBrowser/#/R-CEL-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Caenorhabditis elegans 15377 R-CEL-5696230 https://reactome.org/PathwayBrowser/#/R-CEL-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Caenorhabditis elegans 15377 R-CEL-5696408 https://reactome.org/PathwayBrowser/#/R-CEL-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Caenorhabditis elegans 15377 R-CEL-5696415 https://reactome.org/PathwayBrowser/#/R-CEL-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Caenorhabditis elegans 15377 R-CEL-5696564 https://reactome.org/PathwayBrowser/#/R-CEL-5696564 USP25 deubiquitinates DDX58 IEA Caenorhabditis elegans 15377 R-CEL-5696600 https://reactome.org/PathwayBrowser/#/R-CEL-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Caenorhabditis elegans 15377 R-CEL-5696605 https://reactome.org/PathwayBrowser/#/R-CEL-5696605 USP12, USP26 deubiquitinate AR IEA Caenorhabditis elegans 15377 R-CEL-5696627 https://reactome.org/PathwayBrowser/#/R-CEL-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Caenorhabditis elegans 15377 R-CEL-5696872 https://reactome.org/PathwayBrowser/#/R-CEL-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Caenorhabditis elegans 15377 R-CEL-5696958 https://reactome.org/PathwayBrowser/#/R-CEL-5696958 USP44 deubiquitinates CDC20 IEA Caenorhabditis elegans 15377 R-CEL-5697009 https://reactome.org/PathwayBrowser/#/R-CEL-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Caenorhabditis elegans 15377 R-CEL-6781764 https://reactome.org/PathwayBrowser/#/R-CEL-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Caenorhabditis elegans 15377 R-CEL-6782069 https://reactome.org/PathwayBrowser/#/R-CEL-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Caenorhabditis elegans 15377 R-CEL-6783221 https://reactome.org/PathwayBrowser/#/R-CEL-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Caenorhabditis elegans 15377 R-CEL-6784959 https://reactome.org/PathwayBrowser/#/R-CEL-6784959 BPHL hydrolyses VACV to ACV IEA Caenorhabditis elegans 15377 R-CEL-6786239 https://reactome.org/PathwayBrowser/#/R-CEL-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Caenorhabditis elegans 15377 R-CEL-6786652 https://reactome.org/PathwayBrowser/#/R-CEL-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Caenorhabditis elegans 15377 R-CEL-6787632 https://reactome.org/PathwayBrowser/#/R-CEL-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Caenorhabditis elegans 15377 R-CEL-6788295 https://reactome.org/PathwayBrowser/#/R-CEL-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Caenorhabditis elegans 15377 R-CEL-6788912 https://reactome.org/PathwayBrowser/#/R-CEL-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Caenorhabditis elegans 15377 R-CEL-6789031 https://reactome.org/PathwayBrowser/#/R-CEL-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 15377 R-CEL-6789126 https://reactome.org/PathwayBrowser/#/R-CEL-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 15377 R-CEL-6797627 https://reactome.org/PathwayBrowser/#/R-CEL-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Caenorhabditis elegans 15377 R-CEL-6797630 https://reactome.org/PathwayBrowser/#/R-CEL-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Caenorhabditis elegans 15377 R-CEL-6797653 https://reactome.org/PathwayBrowser/#/R-CEL-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Caenorhabditis elegans 15377 R-CEL-6797955 https://reactome.org/PathwayBrowser/#/R-CEL-6797955 ALDH7A1 oxidises BETALD to BET IEA Caenorhabditis elegans 15377 R-CEL-6799581 https://reactome.org/PathwayBrowser/#/R-CEL-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Caenorhabditis elegans 15377 R-CEL-6799604 https://reactome.org/PathwayBrowser/#/R-CEL-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Caenorhabditis elegans 15377 R-CEL-6799695 https://reactome.org/PathwayBrowser/#/R-CEL-6799695 GPX5,6 reduce H2O2 to H2O IEA Caenorhabditis elegans 15377 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 15377 R-CEL-6803789 https://reactome.org/PathwayBrowser/#/R-CEL-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Caenorhabditis elegans 15377 R-CEL-6805650 https://reactome.org/PathwayBrowser/#/R-CEL-6805650 MTA2-NuRD complex deacetylates TP53 IEA Caenorhabditis elegans 15377 R-CEL-6807008 https://reactome.org/PathwayBrowser/#/R-CEL-6807008 PTPRJ dephosphorylates MET IEA Caenorhabditis elegans 15377 R-CEL-6807118 https://reactome.org/PathwayBrowser/#/R-CEL-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Caenorhabditis elegans 15377 R-CEL-6807206 https://reactome.org/PathwayBrowser/#/R-CEL-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Caenorhabditis elegans 15377 R-CEL-6808464 https://reactome.org/PathwayBrowser/#/R-CEL-6808464 ALDH3B2 oxidises HXAL to PALM IEA Caenorhabditis elegans 15377 R-CEL-6808487 https://reactome.org/PathwayBrowser/#/R-CEL-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 15377 R-CEL-6808496 https://reactome.org/PathwayBrowser/#/R-CEL-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 15377 R-CEL-6809263 https://reactome.org/PathwayBrowser/#/R-CEL-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-6809287 https://reactome.org/PathwayBrowser/#/R-CEL-6809287 NUDT12 hydrolyses NADH to NMNH IEA Caenorhabditis elegans 15377 R-CEL-6809320 https://reactome.org/PathwayBrowser/#/R-CEL-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-6809325 https://reactome.org/PathwayBrowser/#/R-CEL-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-6809720 https://reactome.org/PathwayBrowser/#/R-CEL-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Caenorhabditis elegans 15377 R-CEL-6809777 https://reactome.org/PathwayBrowser/#/R-CEL-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Caenorhabditis elegans 15377 R-CEL-6809778 https://reactome.org/PathwayBrowser/#/R-CEL-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Caenorhabditis elegans 15377 R-CEL-6810076 https://reactome.org/PathwayBrowser/#/R-CEL-6810076 DDO oxidizes D-Asp to OA IEA Caenorhabditis elegans 15377 R-CEL-6810410 https://reactome.org/PathwayBrowser/#/R-CEL-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Caenorhabditis elegans 15377 R-CEL-6810464 https://reactome.org/PathwayBrowser/#/R-CEL-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Caenorhabditis elegans 15377 R-CEL-6810474 https://reactome.org/PathwayBrowser/#/R-CEL-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Caenorhabditis elegans 15377 R-CEL-6811504 https://reactome.org/PathwayBrowser/#/R-CEL-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Caenorhabditis elegans 15377 R-CEL-6813720 https://reactome.org/PathwayBrowser/#/R-CEL-6813720 NCEH1 hydrolyzes cholesterol esters IEA Caenorhabditis elegans 15377 R-CEL-6813740 https://reactome.org/PathwayBrowser/#/R-CEL-6813740 GDE1 hydrolyzes GroPIns IEA Caenorhabditis elegans 15377 R-CEL-6813749 https://reactome.org/PathwayBrowser/#/R-CEL-6813749 ALDH1A1 oxidises GA to DGA IEA Caenorhabditis elegans 15377 R-CEL-6814254 https://reactome.org/PathwayBrowser/#/R-CEL-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Caenorhabditis elegans 15377 R-CEL-6814797 https://reactome.org/PathwayBrowser/#/R-CEL-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Caenorhabditis elegans 15377 R-CEL-69199 https://reactome.org/PathwayBrowser/#/R-CEL-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Caenorhabditis elegans 15377 R-CEL-70262 https://reactome.org/PathwayBrowser/#/R-CEL-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Caenorhabditis elegans 15377 R-CEL-70479 https://reactome.org/PathwayBrowser/#/R-CEL-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Caenorhabditis elegans 15377 R-CEL-70494 https://reactome.org/PathwayBrowser/#/R-CEL-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Caenorhabditis elegans 15377 R-CEL-70569 https://reactome.org/PathwayBrowser/#/R-CEL-70569 arginine + H2O => ornithine + urea [ARG1] IEA Caenorhabditis elegans 15377 R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Caenorhabditis elegans 15377 R-CEL-70599 https://reactome.org/PathwayBrowser/#/R-CEL-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Caenorhabditis elegans 15377 R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Caenorhabditis elegans 15377 R-CEL-70609 https://reactome.org/PathwayBrowser/#/R-CEL-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Caenorhabditis elegans 15377 R-CEL-70785 https://reactome.org/PathwayBrowser/#/R-CEL-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Caenorhabditis elegans 15377 R-CEL-70870 https://reactome.org/PathwayBrowser/#/R-CEL-70870 ECHS1 hydrates methacrylyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-70881 https://reactome.org/PathwayBrowser/#/R-CEL-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Caenorhabditis elegans 15377 R-CEL-70903 https://reactome.org/PathwayBrowser/#/R-CEL-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Caenorhabditis elegans 15377 R-CEL-70906 https://reactome.org/PathwayBrowser/#/R-CEL-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Caenorhabditis elegans 15377 R-CEL-70938 https://reactome.org/PathwayBrowser/#/R-CEL-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Caenorhabditis elegans 15377 R-CEL-70940 https://reactome.org/PathwayBrowser/#/R-CEL-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Caenorhabditis elegans 15377 R-CEL-70941 https://reactome.org/PathwayBrowser/#/R-CEL-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Caenorhabditis elegans 15377 R-CEL-70975 https://reactome.org/PathwayBrowser/#/R-CEL-70975 CS acetylates OA to citrate IEA Caenorhabditis elegans 15377 R-CEL-70982 https://reactome.org/PathwayBrowser/#/R-CEL-70982 FH tetramer hydrates fumarate to L-malate IEA Caenorhabditis elegans 15377 R-CEL-71146 https://reactome.org/PathwayBrowser/#/R-CEL-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Caenorhabditis elegans 15377 R-CEL-71181 https://reactome.org/PathwayBrowser/#/R-CEL-71181 FAH cleaves 4FAA IEA Caenorhabditis elegans 15377 R-CEL-71200 https://reactome.org/PathwayBrowser/#/R-CEL-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Caenorhabditis elegans 15377 R-CEL-71217 https://reactome.org/PathwayBrowser/#/R-CEL-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Caenorhabditis elegans 15377 R-CEL-71260 https://reactome.org/PathwayBrowser/#/R-CEL-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Caenorhabditis elegans 15377 R-CEL-71296 https://reactome.org/PathwayBrowser/#/R-CEL-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Caenorhabditis elegans 15377 R-CEL-71660 https://reactome.org/PathwayBrowser/#/R-CEL-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Caenorhabditis elegans 15377 R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 15377 R-CEL-71723 https://reactome.org/PathwayBrowser/#/R-CEL-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Caenorhabditis elegans 15377 R-CEL-71732 https://reactome.org/PathwayBrowser/#/R-CEL-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Caenorhabditis elegans 15377 R-CEL-73571 https://reactome.org/PathwayBrowser/#/R-CEL-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Caenorhabditis elegans 15377 R-CEL-73577 https://reactome.org/PathwayBrowser/#/R-CEL-73577 CAD hexamer transforms L-Gln to CAP IEA Caenorhabditis elegans 15377 R-CEL-73589 https://reactome.org/PathwayBrowser/#/R-CEL-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Caenorhabditis elegans 15377 R-CEL-73591 https://reactome.org/PathwayBrowser/#/R-CEL-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Caenorhabditis elegans 15377 R-CEL-73608 https://reactome.org/PathwayBrowser/#/R-CEL-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Caenorhabditis elegans 15377 R-CEL-73618 https://reactome.org/PathwayBrowser/#/R-CEL-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Caenorhabditis elegans 15377 R-CEL-73620 https://reactome.org/PathwayBrowser/#/R-CEL-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Caenorhabditis elegans 15377 R-CEL-73647 https://reactome.org/PathwayBrowser/#/R-CEL-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Caenorhabditis elegans 15377 R-CEL-73666 https://reactome.org/PathwayBrowser/#/R-CEL-73666 dUTP + H2O => dUMP + pyrophosphate IEA Caenorhabditis elegans 15377 R-CEL-73792 https://reactome.org/PathwayBrowser/#/R-CEL-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Caenorhabditis elegans 15377 R-CEL-73794 https://reactome.org/PathwayBrowser/#/R-CEL-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Caenorhabditis elegans 15377 R-CEL-73797 https://reactome.org/PathwayBrowser/#/R-CEL-73797 FAICAR => IMP + H2O IEA Caenorhabditis elegans 15377 R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 15377 R-CEL-73815 https://reactome.org/PathwayBrowser/#/R-CEL-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Caenorhabditis elegans 15377 R-CEL-74241 https://reactome.org/PathwayBrowser/#/R-CEL-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Caenorhabditis elegans 15377 R-CEL-74247 https://reactome.org/PathwayBrowser/#/R-CEL-74247 XDH oxidizes hypoxanthine to form xanthine IEA Caenorhabditis elegans 15377 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 15377 R-CEL-74258 https://reactome.org/PathwayBrowser/#/R-CEL-74258 XDH oxidizes xanthine to form urate IEA Caenorhabditis elegans 15377 R-CEL-74948 https://reactome.org/PathwayBrowser/#/R-CEL-74948 PP2A dephosphorylates p-RHO to RHO IEA Caenorhabditis elegans 15377 R-CEL-75872 https://reactome.org/PathwayBrowser/#/R-CEL-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Caenorhabditis elegans 15377 R-CEL-75899 https://reactome.org/PathwayBrowser/#/R-CEL-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Caenorhabditis elegans 15377 R-CEL-76031 https://reactome.org/PathwayBrowser/#/R-CEL-76031 2 H2O2 => O2 + 2 H2O IEA Caenorhabditis elegans 15377 R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 15377 R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 15377 R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 15377 R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 15377 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 15377 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 15377 R-CEL-76590 https://reactome.org/PathwayBrowser/#/R-CEL-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Caenorhabditis elegans 15377 R-CEL-77256 https://reactome.org/PathwayBrowser/#/R-CEL-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-77277 https://reactome.org/PathwayBrowser/#/R-CEL-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-77301 https://reactome.org/PathwayBrowser/#/R-CEL-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-77314 https://reactome.org/PathwayBrowser/#/R-CEL-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-77325 https://reactome.org/PathwayBrowser/#/R-CEL-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-77333 https://reactome.org/PathwayBrowser/#/R-CEL-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-77344 https://reactome.org/PathwayBrowser/#/R-CEL-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Caenorhabditis elegans 15377 R-CEL-77615 https://reactome.org/PathwayBrowser/#/R-CEL-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Caenorhabditis elegans 15377 R-CEL-870437 https://reactome.org/PathwayBrowser/#/R-CEL-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Caenorhabditis elegans 15377 R-CEL-8847579 https://reactome.org/PathwayBrowser/#/R-CEL-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15377 R-CEL-8848339 https://reactome.org/PathwayBrowser/#/R-CEL-8848339 PNPLA5 hydrolyzes TAG IEA Caenorhabditis elegans 15377 R-CEL-8848484 https://reactome.org/PathwayBrowser/#/R-CEL-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Caenorhabditis elegans 15377 R-CEL-8849969 https://reactome.org/PathwayBrowser/#/R-CEL-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Caenorhabditis elegans 15377 R-CEL-8850594 https://reactome.org/PathwayBrowser/#/R-CEL-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Caenorhabditis elegans 15377 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15377 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 15377 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15377 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15377 R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 15377 R-CEL-8853686 https://reactome.org/PathwayBrowser/#/R-CEL-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Caenorhabditis elegans 15377 R-CEL-8854173 https://reactome.org/PathwayBrowser/#/R-CEL-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Caenorhabditis elegans 15377 R-CEL-8854255 https://reactome.org/PathwayBrowser/#/R-CEL-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 15377 R-CEL-8854329 https://reactome.org/PathwayBrowser/#/R-CEL-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 15377 R-CEL-8854612 https://reactome.org/PathwayBrowser/#/R-CEL-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Caenorhabditis elegans 15377 R-CEL-8855490 https://reactome.org/PathwayBrowser/#/R-CEL-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Caenorhabditis elegans 15377 R-CEL-8856951 https://reactome.org/PathwayBrowser/#/R-CEL-8856951 PP2A demethylation by PPME1 IEA Caenorhabditis elegans 15377 R-CEL-8864125 https://reactome.org/PathwayBrowser/#/R-CEL-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Caenorhabditis elegans 15377 R-CEL-8866405 https://reactome.org/PathwayBrowser/#/R-CEL-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 15377 R-CEL-8866542 https://reactome.org/PathwayBrowser/#/R-CEL-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Caenorhabditis elegans 15377 R-CEL-8866601 https://reactome.org/PathwayBrowser/#/R-CEL-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Caenorhabditis elegans 15377 R-CEL-8867047 https://reactome.org/PathwayBrowser/#/R-CEL-8867047 PTPN3 dephosphorylates EPS15 IEA Caenorhabditis elegans 15377 R-CEL-8867658 https://reactome.org/PathwayBrowser/#/R-CEL-8867658 PTPN3 dephosphorylates MAPK12 IEA Caenorhabditis elegans 15377 R-CEL-8868648 https://reactome.org/PathwayBrowser/#/R-CEL-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Caenorhabditis elegans 15377 R-CEL-8868658 https://reactome.org/PathwayBrowser/#/R-CEL-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Caenorhabditis elegans 15377 R-CEL-8868661 https://reactome.org/PathwayBrowser/#/R-CEL-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Caenorhabditis elegans 15377 R-CEL-8869206 https://reactome.org/PathwayBrowser/#/R-CEL-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Caenorhabditis elegans 15377 R-CEL-8874435 https://reactome.org/PathwayBrowser/#/R-CEL-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Caenorhabditis elegans 15377 R-CEL-8878581 https://reactome.org/PathwayBrowser/#/R-CEL-8878581 TYRP1 oxidises DHICA to IQCA IEA Caenorhabditis elegans 15377 R-CEL-8878654 https://reactome.org/PathwayBrowser/#/R-CEL-8878654 ACP6 hydrolyses MYS-LPA IEA Caenorhabditis elegans 15377 R-CEL-888548 https://reactome.org/PathwayBrowser/#/R-CEL-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Caenorhabditis elegans 15377 R-CEL-8932633 https://reactome.org/PathwayBrowser/#/R-CEL-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Caenorhabditis elegans 15377 R-CEL-8933635 https://reactome.org/PathwayBrowser/#/R-CEL-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Caenorhabditis elegans 15377 R-CEL-8936442 https://reactome.org/PathwayBrowser/#/R-CEL-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Caenorhabditis elegans 15377 R-CEL-8937442 https://reactome.org/PathwayBrowser/#/R-CEL-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Caenorhabditis elegans 15377 R-CEL-8943279 https://reactome.org/PathwayBrowser/#/R-CEL-8943279 GGT dimers hydrolyse GSH IEA Caenorhabditis elegans 15377 R-CEL-8952137 https://reactome.org/PathwayBrowser/#/R-CEL-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Caenorhabditis elegans 15377 R-CEL-8952251 https://reactome.org/PathwayBrowser/#/R-CEL-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Caenorhabditis elegans 15377 R-CEL-8953499 https://reactome.org/PathwayBrowser/#/R-CEL-8953499 IMPAD1 hydrolyses PAP to AMP IEA Caenorhabditis elegans 15377 R-CEL-8955817 https://reactome.org/PathwayBrowser/#/R-CEL-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Caenorhabditis elegans 15377 R-CEL-8959510 https://reactome.org/PathwayBrowser/#/R-CEL-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Caenorhabditis elegans 15377 R-CEL-8981637 https://reactome.org/PathwayBrowser/#/R-CEL-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Caenorhabditis elegans 15377 R-CEL-8985594 https://reactome.org/PathwayBrowser/#/R-CEL-8985594 MYO9B inactivates RHOA IEA Caenorhabditis elegans 15377 R-CEL-9008822 https://reactome.org/PathwayBrowser/#/R-CEL-9008822 PPM1D dephosphorylates RUNX2 IEA Caenorhabditis elegans 15377 R-CEL-9009950 https://reactome.org/PathwayBrowser/#/R-CEL-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Caenorhabditis elegans 15377 R-CEL-9013022 https://reactome.org/PathwayBrowser/#/R-CEL-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Caenorhabditis elegans 15377 R-CEL-9013144 https://reactome.org/PathwayBrowser/#/R-CEL-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Caenorhabditis elegans 15377 R-CEL-9013161 https://reactome.org/PathwayBrowser/#/R-CEL-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Caenorhabditis elegans 15377 R-CEL-9013437 https://reactome.org/PathwayBrowser/#/R-CEL-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Caenorhabditis elegans 15377 R-CEL-9014295 https://reactome.org/PathwayBrowser/#/R-CEL-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Caenorhabditis elegans 15377 R-CEL-9014434 https://reactome.org/PathwayBrowser/#/R-CEL-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Caenorhabditis elegans 15377 R-CEL-9014741 https://reactome.org/PathwayBrowser/#/R-CEL-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Caenorhabditis elegans 15377 R-CEL-9017488 https://reactome.org/PathwayBrowser/#/R-CEL-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Caenorhabditis elegans 15377 R-CEL-9018745 https://reactome.org/PathwayBrowser/#/R-CEL-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Caenorhabditis elegans 15377 R-CEL-9018806 https://reactome.org/PathwayBrowser/#/R-CEL-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Caenorhabditis elegans 15377 R-CEL-9018814 https://reactome.org/PathwayBrowser/#/R-CEL-9018814 RHOT1 hydrolyzes GTP IEA Caenorhabditis elegans 15377 R-CEL-9018826 https://reactome.org/PathwayBrowser/#/R-CEL-9018826 RHOT2 hydrolyzes GTP IEA Caenorhabditis elegans 15377 R-CEL-9018862 https://reactome.org/PathwayBrowser/#/R-CEL-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Caenorhabditis elegans 15377 R-CEL-9018868 https://reactome.org/PathwayBrowser/#/R-CEL-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Caenorhabditis elegans 15377 R-CEL-9018877 https://reactome.org/PathwayBrowser/#/R-CEL-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Caenorhabditis elegans 15377 R-CEL-9018895 https://reactome.org/PathwayBrowser/#/R-CEL-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Caenorhabditis elegans 15377 R-CEL-9020252 https://reactome.org/PathwayBrowser/#/R-CEL-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Caenorhabditis elegans 15377 R-CEL-9020253 https://reactome.org/PathwayBrowser/#/R-CEL-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Caenorhabditis elegans 15377 R-CEL-9020257 https://reactome.org/PathwayBrowser/#/R-CEL-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Caenorhabditis elegans 15377 R-CEL-9020258 https://reactome.org/PathwayBrowser/#/R-CEL-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Caenorhabditis elegans 15377 R-CEL-9020270 https://reactome.org/PathwayBrowser/#/R-CEL-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Caenorhabditis elegans 15377 R-CEL-9020271 https://reactome.org/PathwayBrowser/#/R-CEL-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Caenorhabditis elegans 15377 R-CEL-9020273 https://reactome.org/PathwayBrowser/#/R-CEL-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Caenorhabditis elegans 15377 R-CEL-9024890 https://reactome.org/PathwayBrowser/#/R-CEL-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Caenorhabditis elegans 15377 R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans 15377 R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 15377 R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 15377 R-CEL-9033491 https://reactome.org/PathwayBrowser/#/R-CEL-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Caenorhabditis elegans 15377 R-CEL-9034539 https://reactome.org/PathwayBrowser/#/R-CEL-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Caenorhabditis elegans 15377 R-CEL-917841 https://reactome.org/PathwayBrowser/#/R-CEL-917841 Acidification of Tf:TfR1 containing endosome IEA Caenorhabditis elegans 15377 R-CEL-917979 https://reactome.org/PathwayBrowser/#/R-CEL-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-CEL-936883 https://reactome.org/PathwayBrowser/#/R-CEL-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Caenorhabditis elegans 15377 R-CEL-936895 https://reactome.org/PathwayBrowser/#/R-CEL-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Caenorhabditis elegans 15377 R-CEL-939763 https://reactome.org/PathwayBrowser/#/R-CEL-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-947531 https://reactome.org/PathwayBrowser/#/R-CEL-947531 Molybdenum ion transfer onto molybdopterin IEA Caenorhabditis elegans 15377 R-CEL-947535 https://reactome.org/PathwayBrowser/#/R-CEL-947535 Cyclisation of GTP to precursor Z IEA Caenorhabditis elegans 15377 R-CEL-947591 https://reactome.org/PathwayBrowser/#/R-CEL-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Caenorhabditis elegans 15377 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 15377 R-CEL-9620103 https://reactome.org/PathwayBrowser/#/R-CEL-9620103 ALDH2 transforms GTN to NO IEA Caenorhabditis elegans 15377 R-CEL-9624893 https://reactome.org/PathwayBrowser/#/R-CEL-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Caenorhabditis elegans 15377 R-CEL-9629675 https://reactome.org/PathwayBrowser/#/R-CEL-9629675 PDE3A hydrolyses cAMP to AMP IEA Caenorhabditis elegans 15377 R-CEL-9638075 https://reactome.org/PathwayBrowser/#/R-CEL-9638075 HEXB cleaves the terminal GalNAc from DS IEA Caenorhabditis elegans 15377 R-CEL-9638076 https://reactome.org/PathwayBrowser/#/R-CEL-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Caenorhabditis elegans 15377 R-CEL-9638078 https://reactome.org/PathwayBrowser/#/R-CEL-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Caenorhabditis elegans 15377 R-CEL-9644869 https://reactome.org/PathwayBrowser/#/R-CEL-9644869 p-S54-PDE4B hydrolyses cAMP IEA Caenorhabditis elegans 15377 R-CEL-9647994 https://reactome.org/PathwayBrowser/#/R-CEL-9647994 RAS proteins are depalmitoylated IEA Caenorhabditis elegans 15377 R-CEL-965079 https://reactome.org/PathwayBrowser/#/R-CEL-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Caenorhabditis elegans 15377 R-CEL-9653514 https://reactome.org/PathwayBrowser/#/R-CEL-9653514 USP17L2 deubiquitinates RCE1 IEA Caenorhabditis elegans 15377 R-CEL-9656891 https://reactome.org/PathwayBrowser/#/R-CEL-9656891 OPN1SW binds 11cRAL IEA Caenorhabditis elegans 15377 R-CEL-9656893 https://reactome.org/PathwayBrowser/#/R-CEL-9656893 OPN1MW binds 11cRAL IEA Caenorhabditis elegans 15377 R-CEL-9658445 https://reactome.org/PathwayBrowser/#/R-CEL-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Caenorhabditis elegans 15377 R-CEL-9661417 https://reactome.org/PathwayBrowser/#/R-CEL-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-CEL-9693282 https://reactome.org/PathwayBrowser/#/R-CEL-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Caenorhabditis elegans 15377 R-CEL-9701565 https://reactome.org/PathwayBrowser/#/R-CEL-9701565 HDACs deacetylate p-STAT3 dimers IEA Caenorhabditis elegans 15377 R-CEL-9705507 https://reactome.org/PathwayBrowser/#/R-CEL-9705507 PDE3B hydrolyses cAMP to AMP IEA Caenorhabditis elegans 15377 R-CEL-9706399 https://reactome.org/PathwayBrowser/#/R-CEL-9706399 RHOBTB3 hydrolyzes ATP IEA Caenorhabditis elegans 15377 R-CEL-9708261 https://reactome.org/PathwayBrowser/#/R-CEL-9708261 PDE4A hydrolyses cAMP to AMP IEA Caenorhabditis elegans 15377 R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 15377 R-CEL-9727349 https://reactome.org/PathwayBrowser/#/R-CEL-9727349 XDH dehydrogenates xanthine to form urate IEA Caenorhabditis elegans 15377 R-CEL-9727567 https://reactome.org/PathwayBrowser/#/R-CEL-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Caenorhabditis elegans 15377 R-CEL-9731661 https://reactome.org/PathwayBrowser/#/R-CEL-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Caenorhabditis elegans 15377 R-CEL-9748945 https://reactome.org/PathwayBrowser/#/R-CEL-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Caenorhabditis elegans 15377 R-CEL-9748957 https://reactome.org/PathwayBrowser/#/R-CEL-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Caenorhabditis elegans 15377 R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 15377 R-CEL-9749609 https://reactome.org/PathwayBrowser/#/R-CEL-9749609 BCHE hydrolyzes ASA- IEA Caenorhabditis elegans 15377 R-CEL-9749647 https://reactome.org/PathwayBrowser/#/R-CEL-9749647 CES2 hydrolyzes ASA- IEA Caenorhabditis elegans 15377 R-CEL-9749792 https://reactome.org/PathwayBrowser/#/R-CEL-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Caenorhabditis elegans 15377 R-CEL-9749986 https://reactome.org/PathwayBrowser/#/R-CEL-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Caenorhabditis elegans 15377 R-CEL-9750016 https://reactome.org/PathwayBrowser/#/R-CEL-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Caenorhabditis elegans 15377 R-CEL-9750546 https://reactome.org/PathwayBrowser/#/R-CEL-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-CEL-9750617 https://reactome.org/PathwayBrowser/#/R-CEL-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-CEL-9750656 https://reactome.org/PathwayBrowser/#/R-CEL-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Caenorhabditis elegans 15377 R-CEL-9753278 https://reactome.org/PathwayBrowser/#/R-CEL-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 15377 R-CEL-9753280 https://reactome.org/PathwayBrowser/#/R-CEL-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Caenorhabditis elegans 15377 R-CEL-9753283 https://reactome.org/PathwayBrowser/#/R-CEL-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 15377 R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans 15377 R-CEL-9753632 https://reactome.org/PathwayBrowser/#/R-CEL-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Caenorhabditis elegans 15377 R-CEL-9753634 https://reactome.org/PathwayBrowser/#/R-CEL-9753634 GGT dimers hydrolyse APAP-SG IEA Caenorhabditis elegans 15377 R-CEL-9753944 https://reactome.org/PathwayBrowser/#/R-CEL-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Caenorhabditis elegans 15377 R-CEL-9754964 https://reactome.org/PathwayBrowser/#/R-CEL-9754964 ADA deamidates RBV IEA Caenorhabditis elegans 15377 R-CEL-9755030 https://reactome.org/PathwayBrowser/#/R-CEL-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Caenorhabditis elegans 15377 R-CEL-9755078 https://reactome.org/PathwayBrowser/#/R-CEL-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Caenorhabditis elegans 15377 R-CEL-975594 https://reactome.org/PathwayBrowser/#/R-CEL-975594 PLB1 hydrolyses RPALM to atROL IEA Caenorhabditis elegans 15377 R-CEL-9756177 https://reactome.org/PathwayBrowser/#/R-CEL-9756177 PON1,3 hydrolyse ATVL to ATV IEA Caenorhabditis elegans 15377 R-CEL-977324 https://reactome.org/PathwayBrowser/#/R-CEL-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Caenorhabditis elegans 15377 R-CEL-9794120 https://reactome.org/PathwayBrowser/#/R-CEL-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Caenorhabditis elegans 15377 R-CEL-9794572 https://reactome.org/PathwayBrowser/#/R-CEL-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Caenorhabditis elegans 15377 R-CEL-983144 https://reactome.org/PathwayBrowser/#/R-CEL-983144 Transport of Antigen peptide in to ER IEA Caenorhabditis elegans 15377 R-CEL-9837419 https://reactome.org/PathwayBrowser/#/R-CEL-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Caenorhabditis elegans 15377 R-CEL-9838004 https://reactome.org/PathwayBrowser/#/R-CEL-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Caenorhabditis elegans 15377 R-CEL-9838081 https://reactome.org/PathwayBrowser/#/R-CEL-9838081 LONP1 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 15377 R-CEL-9838289 https://reactome.org/PathwayBrowser/#/R-CEL-9838289 CLPXP degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 15377 R-CEL-9839059 https://reactome.org/PathwayBrowser/#/R-CEL-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Caenorhabditis elegans 15377 R-CEL-9839105 https://reactome.org/PathwayBrowser/#/R-CEL-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 15377 R-CEL-9839113 https://reactome.org/PathwayBrowser/#/R-CEL-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Caenorhabditis elegans 15377 R-CEL-9840795 https://reactome.org/PathwayBrowser/#/R-CEL-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Caenorhabditis elegans 15377 R-CEL-9840833 https://reactome.org/PathwayBrowser/#/R-CEL-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Caenorhabditis elegans 15377 R-CEL-9840884 https://reactome.org/PathwayBrowser/#/R-CEL-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Caenorhabditis elegans 15377 R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 15377 R-CEL-9843721 https://reactome.org/PathwayBrowser/#/R-CEL-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Caenorhabditis elegans 15377 R-CEL-9853385 https://reactome.org/PathwayBrowser/#/R-CEL-9853385 PPP1CC dephosphorylates PLK1 IEA Caenorhabditis elegans 15377 R-CEL-9861626 https://reactome.org/PathwayBrowser/#/R-CEL-9861626 SIRT4 cleaves lipoyl from DLAT IEA Caenorhabditis elegans 15377 R-CEL-9861725 https://reactome.org/PathwayBrowser/#/R-CEL-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Caenorhabditis elegans 15377 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 15377 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 15377 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 15377 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 15377 R-CFA-109415 https://reactome.org/PathwayBrowser/#/R-CFA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Canis familiaris 15377 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 15377 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 15377 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 15377 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 15377 R-CFA-111742 https://reactome.org/PathwayBrowser/#/R-CFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 15377 R-CFA-111751 https://reactome.org/PathwayBrowser/#/R-CFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 15377 R-CFA-111804 https://reactome.org/PathwayBrowser/#/R-CFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 15377 R-CFA-111879 https://reactome.org/PathwayBrowser/#/R-CFA-111879 PIP2 hydrolysis IEA Canis familiaris 15377 R-CFA-111883 https://reactome.org/PathwayBrowser/#/R-CFA-111883 Hydrolysis of phosphatidylcholine IEA Canis familiaris 15377 R-CFA-111955 https://reactome.org/PathwayBrowser/#/R-CFA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Canis familiaris 15377 R-CFA-111962 https://reactome.org/PathwayBrowser/#/R-CFA-111962 PDE4A,C,D hydrolyse cAMP IEA Canis familiaris 15377 R-CFA-112037 https://reactome.org/PathwayBrowser/#/R-CFA-112037 Inactivation of PLC beta IEA Canis familiaris 15377 R-CFA-113503 https://reactome.org/PathwayBrowser/#/R-CFA-113503 PP2A mediated localization of RB1 protein in chromatin IEA Canis familiaris 15377 R-CFA-1169192 https://reactome.org/PathwayBrowser/#/R-CFA-1169192 PTP1B dephosphorylates GHR IEA Canis familiaris 15377 R-CFA-1183128 https://reactome.org/PathwayBrowser/#/R-CFA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Canis familiaris 15377 R-CFA-1237045 https://reactome.org/PathwayBrowser/#/R-CFA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Canis familiaris 15377 R-CFA-1237047 https://reactome.org/PathwayBrowser/#/R-CFA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Canis familiaris 15377 R-CFA-1237059 https://reactome.org/PathwayBrowser/#/R-CFA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Canis familiaris 15377 R-CFA-1237081 https://reactome.org/PathwayBrowser/#/R-CFA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Canis familiaris 15377 R-CFA-1237129 https://reactome.org/PathwayBrowser/#/R-CFA-1237129 Acireductone is created IEA Canis familiaris 15377 R-CFA-1247910 https://reactome.org/PathwayBrowser/#/R-CFA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Canis familiaris 15377 R-CFA-1247935 https://reactome.org/PathwayBrowser/#/R-CFA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Canis familiaris 15377 R-CFA-1363274 https://reactome.org/PathwayBrowser/#/R-CFA-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Canis familiaris 15377 R-CFA-1363276 https://reactome.org/PathwayBrowser/#/R-CFA-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Canis familiaris 15377 R-CFA-1369065 https://reactome.org/PathwayBrowser/#/R-CFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Canis familiaris 15377 R-CFA-139906 https://reactome.org/PathwayBrowser/#/R-CFA-139906 Activation of BAD by calcineurin IEA Canis familiaris 15377 R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 15377 R-CFA-140359 https://reactome.org/PathwayBrowser/#/R-CFA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Canis familiaris 15377 R-CFA-141186 https://reactome.org/PathwayBrowser/#/R-CFA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Canis familiaris 15377 R-CFA-141200 https://reactome.org/PathwayBrowser/#/R-CFA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Canis familiaris 15377 R-CFA-141202 https://reactome.org/PathwayBrowser/#/R-CFA-141202 MAOB:FAD oxidatively deaminates TYR IEA Canis familiaris 15377 R-CFA-141341 https://reactome.org/PathwayBrowser/#/R-CFA-141341 SMOX-3 oxidises SPN to SPM IEA Canis familiaris 15377 R-CFA-141348 https://reactome.org/PathwayBrowser/#/R-CFA-141348 PAO:FAD oxidises NASPM to PTCN IEA Canis familiaris 15377 R-CFA-141351 https://reactome.org/PathwayBrowser/#/R-CFA-141351 PAOX:FAD oxidises NASPN to SPM IEA Canis familiaris 15377 R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 15377 R-CFA-1454916 https://reactome.org/PathwayBrowser/#/R-CFA-1454916 The ABCC family mediates organic anion transport IEA Canis familiaris 15377 R-CFA-1454928 https://reactome.org/PathwayBrowser/#/R-CFA-1454928 ABCG4 may mediate cholesterol efflux IEA Canis familiaris 15377 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 15377 R-CFA-1467466 https://reactome.org/PathwayBrowser/#/R-CFA-1467466 ABCA4 mediates atRAL transport IEA Canis familiaris 15377 R-CFA-1474146 https://reactome.org/PathwayBrowser/#/R-CFA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Canis familiaris 15377 R-CFA-1475017 https://reactome.org/PathwayBrowser/#/R-CFA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Canis familiaris 15377 R-CFA-1475022 https://reactome.org/PathwayBrowser/#/R-CFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Canis familiaris 15377 R-CFA-1475025 https://reactome.org/PathwayBrowser/#/R-CFA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Canis familiaris 15377 R-CFA-1475026 https://reactome.org/PathwayBrowser/#/R-CFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Canis familiaris 15377 R-CFA-1475028 https://reactome.org/PathwayBrowser/#/R-CFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Canis familiaris 15377 R-CFA-1475032 https://reactome.org/PathwayBrowser/#/R-CFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Canis familiaris 15377 R-CFA-1475435 https://reactome.org/PathwayBrowser/#/R-CFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Canis familiaris 15377 R-CFA-1475436 https://reactome.org/PathwayBrowser/#/R-CFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Canis familiaris 15377 R-CFA-1482543 https://reactome.org/PathwayBrowser/#/R-CFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Canis familiaris 15377 R-CFA-1482604 https://reactome.org/PathwayBrowser/#/R-CFA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Canis familiaris 15377 R-CFA-1482612 https://reactome.org/PathwayBrowser/#/R-CFA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 15377 R-CFA-1482656 https://reactome.org/PathwayBrowser/#/R-CFA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Canis familiaris 15377 R-CFA-1482685 https://reactome.org/PathwayBrowser/#/R-CFA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 15377 R-CFA-1482745 https://reactome.org/PathwayBrowser/#/R-CFA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Canis familiaris 15377 R-CFA-1482759 https://reactome.org/PathwayBrowser/#/R-CFA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Canis familiaris 15377 R-CFA-1482771 https://reactome.org/PathwayBrowser/#/R-CFA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Canis familiaris 15377 R-CFA-1482777 https://reactome.org/PathwayBrowser/#/R-CFA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Canis familiaris 15377 R-CFA-1482811 https://reactome.org/PathwayBrowser/#/R-CFA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Canis familiaris 15377 R-CFA-1482816 https://reactome.org/PathwayBrowser/#/R-CFA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Canis familiaris 15377 R-CFA-1482825 https://reactome.org/PathwayBrowser/#/R-CFA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Canis familiaris 15377 R-CFA-1482828 https://reactome.org/PathwayBrowser/#/R-CFA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Canis familiaris 15377 R-CFA-1482847 https://reactome.org/PathwayBrowser/#/R-CFA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Canis familiaris 15377 R-CFA-1482856 https://reactome.org/PathwayBrowser/#/R-CFA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Canis familiaris 15377 R-CFA-1482862 https://reactome.org/PathwayBrowser/#/R-CFA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Canis familiaris 15377 R-CFA-1482884 https://reactome.org/PathwayBrowser/#/R-CFA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Canis familiaris 15377 R-CFA-1482887 https://reactome.org/PathwayBrowser/#/R-CFA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Canis familiaris 15377 R-CFA-1482897 https://reactome.org/PathwayBrowser/#/R-CFA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Canis familiaris 15377 R-CFA-1482900 https://reactome.org/PathwayBrowser/#/R-CFA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Canis familiaris 15377 R-CFA-1482920 https://reactome.org/PathwayBrowser/#/R-CFA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Canis familiaris 15377 R-CFA-1482932 https://reactome.org/PathwayBrowser/#/R-CFA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Canis familiaris 15377 R-CFA-1483096 https://reactome.org/PathwayBrowser/#/R-CFA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Canis familiaris 15377 R-CFA-1483159 https://reactome.org/PathwayBrowser/#/R-CFA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Canis familiaris 15377 R-CFA-1483182 https://reactome.org/PathwayBrowser/#/R-CFA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Canis familiaris 15377 R-CFA-1483203 https://reactome.org/PathwayBrowser/#/R-CFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Canis familiaris 15377 R-CFA-156526 https://reactome.org/PathwayBrowser/#/R-CFA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Canis familiaris 15377 R-CFA-159425 https://reactome.org/PathwayBrowser/#/R-CFA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 15377 R-CFA-159752 https://reactome.org/PathwayBrowser/#/R-CFA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Canis familiaris 15377 R-CFA-159761 https://reactome.org/PathwayBrowser/#/R-CFA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Canis familiaris 15377 R-CFA-159795 https://reactome.org/PathwayBrowser/#/R-CFA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Canis familiaris 15377 R-CFA-159803 https://reactome.org/PathwayBrowser/#/R-CFA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Canis familiaris 15377 R-CFA-159819 https://reactome.org/PathwayBrowser/#/R-CFA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Canis familiaris 15377 R-CFA-159826 https://reactome.org/PathwayBrowser/#/R-CFA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Canis familiaris 15377 R-CFA-1602368 https://reactome.org/PathwayBrowser/#/R-CFA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Canis familiaris 15377 R-CFA-1602374 https://reactome.org/PathwayBrowser/#/R-CFA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Canis familiaris 15377 R-CFA-1602377 https://reactome.org/PathwayBrowser/#/R-CFA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Canis familiaris 15377 R-CFA-1602398 https://reactome.org/PathwayBrowser/#/R-CFA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Canis familiaris 15377 R-CFA-1602399 https://reactome.org/PathwayBrowser/#/R-CFA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Canis familiaris 15377 R-CFA-1602417 https://reactome.org/PathwayBrowser/#/R-CFA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Canis familiaris 15377 R-CFA-1602446 https://reactome.org/PathwayBrowser/#/R-CFA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Canis familiaris 15377 R-CFA-1605591 https://reactome.org/PathwayBrowser/#/R-CFA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Canis familiaris 15377 R-CFA-1605595 https://reactome.org/PathwayBrowser/#/R-CFA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Canis familiaris 15377 R-CFA-1605624 https://reactome.org/PathwayBrowser/#/R-CFA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Canis familiaris 15377 R-CFA-1605632 https://reactome.org/PathwayBrowser/#/R-CFA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Canis familiaris 15377 R-CFA-1605723 https://reactome.org/PathwayBrowser/#/R-CFA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Canis familiaris 15377 R-CFA-1605724 https://reactome.org/PathwayBrowser/#/R-CFA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Canis familiaris 15377 R-CFA-1605736 https://reactome.org/PathwayBrowser/#/R-CFA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Canis familiaris 15377 R-CFA-1605768 https://reactome.org/PathwayBrowser/#/R-CFA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Canis familiaris 15377 R-CFA-1605797 https://reactome.org/PathwayBrowser/#/R-CFA-1605797 SMPD1 hydrolyzes SPHM IEA Canis familiaris 15377 R-CFA-1606273 https://reactome.org/PathwayBrowser/#/R-CFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Canis familiaris 15377 R-CFA-1606288 https://reactome.org/PathwayBrowser/#/R-CFA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Canis familiaris 15377 R-CFA-1606312 https://reactome.org/PathwayBrowser/#/R-CFA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Canis familiaris 15377 R-CFA-1606564 https://reactome.org/PathwayBrowser/#/R-CFA-1606564 GALC hydrolyzes GalCer IEA Canis familiaris 15377 R-CFA-1606583 https://reactome.org/PathwayBrowser/#/R-CFA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Canis familiaris 15377 R-CFA-1606602 https://reactome.org/PathwayBrowser/#/R-CFA-1606602 ASAH1 hydrolyzes ceramide IEA Canis familiaris 15377 R-CFA-1606789 https://reactome.org/PathwayBrowser/#/R-CFA-1606789 ARSB hydrolyses DS IEA Canis familiaris 15377 R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 15377 R-CFA-1606839 https://reactome.org/PathwayBrowser/#/R-CFA-1606839 ARSC hydrolyzes steroid sulfates IEA Canis familiaris 15377 R-CFA-1614524 https://reactome.org/PathwayBrowser/#/R-CFA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Canis familiaris 15377 R-CFA-1614544 https://reactome.org/PathwayBrowser/#/R-CFA-1614544 Sulfite is oxidized to sulfate IEA Canis familiaris 15377 R-CFA-1614583 https://reactome.org/PathwayBrowser/#/R-CFA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Canis familiaris 15377 R-CFA-1614605 https://reactome.org/PathwayBrowser/#/R-CFA-1614605 Persulfide sulfur is dioxygenated IEA Canis familiaris 15377 R-CFA-1614614 https://reactome.org/PathwayBrowser/#/R-CFA-1614614 Cysteine is degraded to serine and H2S IEA Canis familiaris 15377 R-CFA-1614631 https://reactome.org/PathwayBrowser/#/R-CFA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Canis familiaris 15377 R-CFA-162425 https://reactome.org/PathwayBrowser/#/R-CFA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Canis familiaris 15377 R-CFA-162729 https://reactome.org/PathwayBrowser/#/R-CFA-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Canis familiaris 15377 R-CFA-162857 https://reactome.org/PathwayBrowser/#/R-CFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Canis familiaris 15377 R-CFA-1630304 https://reactome.org/PathwayBrowser/#/R-CFA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Canis familiaris 15377 R-CFA-1630306 https://reactome.org/PathwayBrowser/#/R-CFA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Canis familiaris 15377 R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 15377 R-CFA-1638032 https://reactome.org/PathwayBrowser/#/R-CFA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Canis familiaris 15377 R-CFA-1638053 https://reactome.org/PathwayBrowser/#/R-CFA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Canis familiaris 15377 R-CFA-1638821 https://reactome.org/PathwayBrowser/#/R-CFA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Canis familiaris 15377 R-CFA-1640164 https://reactome.org/PathwayBrowser/#/R-CFA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Canis familiaris 15377 R-CFA-164832 https://reactome.org/PathwayBrowser/#/R-CFA-164832 ATPase synthesizes ATP IEA Canis familiaris 15377 R-CFA-1655453 https://reactome.org/PathwayBrowser/#/R-CFA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Canis familiaris 15377 R-CFA-1667005 https://reactome.org/PathwayBrowser/#/R-CFA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Canis familiaris 15377 R-CFA-1675795 https://reactome.org/PathwayBrowser/#/R-CFA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Canis familiaris 15377 R-CFA-1675824 https://reactome.org/PathwayBrowser/#/R-CFA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Canis familiaris 15377 R-CFA-1675836 https://reactome.org/PathwayBrowser/#/R-CFA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Canis familiaris 15377 R-CFA-1675949 https://reactome.org/PathwayBrowser/#/R-CFA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Canis familiaris 15377 R-CFA-1675988 https://reactome.org/PathwayBrowser/#/R-CFA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Canis familiaris 15377 R-CFA-1675994 https://reactome.org/PathwayBrowser/#/R-CFA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Canis familiaris 15377 R-CFA-1676005 https://reactome.org/PathwayBrowser/#/R-CFA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Canis familiaris 15377 R-CFA-1676020 https://reactome.org/PathwayBrowser/#/R-CFA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Canis familiaris 15377 R-CFA-1676065 https://reactome.org/PathwayBrowser/#/R-CFA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Canis familiaris 15377 R-CFA-1676105 https://reactome.org/PathwayBrowser/#/R-CFA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Canis familiaris 15377 R-CFA-1676114 https://reactome.org/PathwayBrowser/#/R-CFA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Canis familiaris 15377 R-CFA-1676124 https://reactome.org/PathwayBrowser/#/R-CFA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Canis familiaris 15377 R-CFA-1676141 https://reactome.org/PathwayBrowser/#/R-CFA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Canis familiaris 15377 R-CFA-1676149 https://reactome.org/PathwayBrowser/#/R-CFA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Canis familiaris 15377 R-CFA-1676162 https://reactome.org/PathwayBrowser/#/R-CFA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Canis familiaris 15377 R-CFA-1676164 https://reactome.org/PathwayBrowser/#/R-CFA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Canis familiaris 15377 R-CFA-1676174 https://reactome.org/PathwayBrowser/#/R-CFA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Canis familiaris 15377 R-CFA-1676177 https://reactome.org/PathwayBrowser/#/R-CFA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Canis familiaris 15377 R-CFA-1676203 https://reactome.org/PathwayBrowser/#/R-CFA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Canis familiaris 15377 R-CFA-1676204 https://reactome.org/PathwayBrowser/#/R-CFA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Canis familiaris 15377 R-CFA-1678650 https://reactome.org/PathwayBrowser/#/R-CFA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Canis familiaris 15377 R-CFA-1678708 https://reactome.org/PathwayBrowser/#/R-CFA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Canis familiaris 15377 R-CFA-1678716 https://reactome.org/PathwayBrowser/#/R-CFA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Canis familiaris 15377 R-CFA-1678742 https://reactome.org/PathwayBrowser/#/R-CFA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Canis familiaris 15377 R-CFA-1678854 https://reactome.org/PathwayBrowser/#/R-CFA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Canis familiaris 15377 R-CFA-170153 https://reactome.org/PathwayBrowser/#/R-CFA-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Canis familiaris 15377 R-CFA-170158 https://reactome.org/PathwayBrowser/#/R-CFA-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Canis familiaris 15377 R-CFA-170161 https://reactome.org/PathwayBrowser/#/R-CFA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Canis familiaris 15377 R-CFA-173597 https://reactome.org/PathwayBrowser/#/R-CFA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Canis familiaris 15377 R-CFA-173739 https://reactome.org/PathwayBrowser/#/R-CFA-173739 Spontaneous hydrolysis of C3 thioester IEA Canis familiaris 15377 R-CFA-174110 https://reactome.org/PathwayBrowser/#/R-CFA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Canis familiaris 15377 R-CFA-174124 https://reactome.org/PathwayBrowser/#/R-CFA-174124 Dephosphorylation of phospho-Cdh1 IEA Canis familiaris 15377 R-CFA-174391 https://reactome.org/PathwayBrowser/#/R-CFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Canis familiaris 15377 R-CFA-174401 https://reactome.org/PathwayBrowser/#/R-CFA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Canis familiaris 15377 R-CFA-174438 https://reactome.org/PathwayBrowser/#/R-CFA-174438 Formation of the Flap Intermediate on the C-strand IEA Canis familiaris 15377 R-CFA-174439 https://reactome.org/PathwayBrowser/#/R-CFA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Canis familiaris 15377 R-CFA-176606 https://reactome.org/PathwayBrowser/#/R-CFA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Canis familiaris 15377 R-CFA-177923 https://reactome.org/PathwayBrowser/#/R-CFA-177923 Sustained activation of SRC kinase by SHP2 IEA Canis familiaris 15377 R-CFA-177924 https://reactome.org/PathwayBrowser/#/R-CFA-177924 Dephosphorylation of Gab1 by SHP2 IEA Canis familiaris 15377 R-CFA-177926 https://reactome.org/PathwayBrowser/#/R-CFA-177926 Dephosphorylation of PAG by SHP2 IEA Canis familiaris 15377 R-CFA-177935 https://reactome.org/PathwayBrowser/#/R-CFA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Canis familiaris 15377 R-CFA-1793182 https://reactome.org/PathwayBrowser/#/R-CFA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Canis familiaris 15377 R-CFA-1793186 https://reactome.org/PathwayBrowser/#/R-CFA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Canis familiaris 15377 R-CFA-1793207 https://reactome.org/PathwayBrowser/#/R-CFA-1793207 ARSB hydrolyses C4S/C6S chains IEA Canis familiaris 15377 R-CFA-1793209 https://reactome.org/PathwayBrowser/#/R-CFA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Canis familiaris 15377 R-CFA-1855154 https://reactome.org/PathwayBrowser/#/R-CFA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 15377 R-CFA-1855159 https://reactome.org/PathwayBrowser/#/R-CFA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Canis familiaris 15377 R-CFA-1855163 https://reactome.org/PathwayBrowser/#/R-CFA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Canis familiaris 15377 R-CFA-1855165 https://reactome.org/PathwayBrowser/#/R-CFA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 15377 R-CFA-1855166 https://reactome.org/PathwayBrowser/#/R-CFA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Canis familiaris 15377 R-CFA-1855171 https://reactome.org/PathwayBrowser/#/R-CFA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Canis familiaris 15377 R-CFA-1855174 https://reactome.org/PathwayBrowser/#/R-CFA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Canis familiaris 15377 R-CFA-1855177 https://reactome.org/PathwayBrowser/#/R-CFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Canis familiaris 15377 R-CFA-1855180 https://reactome.org/PathwayBrowser/#/R-CFA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Canis familiaris 15377 R-CFA-1855198 https://reactome.org/PathwayBrowser/#/R-CFA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 15377 R-CFA-1855200 https://reactome.org/PathwayBrowser/#/R-CFA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Canis familiaris 15377 R-CFA-1855202 https://reactome.org/PathwayBrowser/#/R-CFA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Canis familiaris 15377 R-CFA-1855205 https://reactome.org/PathwayBrowser/#/R-CFA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Canis familiaris 15377 R-CFA-1855208 https://reactome.org/PathwayBrowser/#/R-CFA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Canis familiaris 15377 R-CFA-1855210 https://reactome.org/PathwayBrowser/#/R-CFA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 15377 R-CFA-1855211 https://reactome.org/PathwayBrowser/#/R-CFA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 15377 R-CFA-1855213 https://reactome.org/PathwayBrowser/#/R-CFA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Canis familiaris 15377 R-CFA-1855214 https://reactome.org/PathwayBrowser/#/R-CFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Canis familiaris 15377 R-CFA-1855218 https://reactome.org/PathwayBrowser/#/R-CFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Canis familiaris 15377 R-CFA-1855219 https://reactome.org/PathwayBrowser/#/R-CFA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 15377 R-CFA-1855221 https://reactome.org/PathwayBrowser/#/R-CFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Canis familiaris 15377 R-CFA-1855222 https://reactome.org/PathwayBrowser/#/R-CFA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Canis familiaris 15377 R-CFA-1855225 https://reactome.org/PathwayBrowser/#/R-CFA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Canis familiaris 15377 R-CFA-1855232 https://reactome.org/PathwayBrowser/#/R-CFA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Canis familiaris 15377 R-CFA-1861788 https://reactome.org/PathwayBrowser/#/R-CFA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Canis familiaris 15377 R-CFA-1861789 https://reactome.org/PathwayBrowser/#/R-CFA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Canis familiaris 15377 R-CFA-188979 https://reactome.org/PathwayBrowser/#/R-CFA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Canis familiaris 15377 R-CFA-189053 https://reactome.org/PathwayBrowser/#/R-CFA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Canis familiaris 15377 R-CFA-189062 https://reactome.org/PathwayBrowser/#/R-CFA-189062 lactose + H2O => D-glucose + D-galactose IEA Canis familiaris 15377 R-CFA-189069 https://reactome.org/PathwayBrowser/#/R-CFA-189069 sucrose + H2O => glucose + fructose IEA Canis familiaris 15377 R-CFA-189102 https://reactome.org/PathwayBrowser/#/R-CFA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Canis familiaris 15377 R-CFA-189398 https://reactome.org/PathwayBrowser/#/R-CFA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Canis familiaris 15377 R-CFA-189406 https://reactome.org/PathwayBrowser/#/R-CFA-189406 4 PBGs bind to form HMB IEA Canis familiaris 15377 R-CFA-189421 https://reactome.org/PathwayBrowser/#/R-CFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Canis familiaris 15377 R-CFA-189439 https://reactome.org/PathwayBrowser/#/R-CFA-189439 ALAD condenses 2 dALAs to form PBG IEA Canis familiaris 15377 R-CFA-189488 https://reactome.org/PathwayBrowser/#/R-CFA-189488 UROS transforms HMB to URO3 IEA Canis familiaris 15377 R-CFA-191101 https://reactome.org/PathwayBrowser/#/R-CFA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Canis familiaris 15377 R-CFA-191108 https://reactome.org/PathwayBrowser/#/R-CFA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Canis familiaris 15377 R-CFA-191114 https://reactome.org/PathwayBrowser/#/R-CFA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Canis familiaris 15377 R-CFA-191116 https://reactome.org/PathwayBrowser/#/R-CFA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Canis familiaris 15377 R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 15377 R-CFA-191323 https://reactome.org/PathwayBrowser/#/R-CFA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Canis familiaris 15377 R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 15377 R-CFA-191999 https://reactome.org/PathwayBrowser/#/R-CFA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Canis familiaris 15377 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 15377 R-CFA-192054 https://reactome.org/PathwayBrowser/#/R-CFA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Canis familiaris 15377 R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 15377 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 15377 R-CFA-192123 https://reactome.org/PathwayBrowser/#/R-CFA-192123 CYP27A1 27-hydroxylates CHOL IEA Canis familiaris 15377 R-CFA-192157 https://reactome.org/PathwayBrowser/#/R-CFA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Canis familiaris 15377 R-CFA-192178 https://reactome.org/PathwayBrowser/#/R-CFA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Canis familiaris 15377 R-CFA-192331 https://reactome.org/PathwayBrowser/#/R-CFA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Canis familiaris 15377 R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 15377 R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 15377 R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 15377 R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 15377 R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 15377 R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 15377 R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 15377 R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 15377 R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 15377 R-CFA-193362 https://reactome.org/PathwayBrowser/#/R-CFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Canis familiaris 15377 R-CFA-193385 https://reactome.org/PathwayBrowser/#/R-CFA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Canis familiaris 15377 R-CFA-193393 https://reactome.org/PathwayBrowser/#/R-CFA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Canis familiaris 15377 R-CFA-193460 https://reactome.org/PathwayBrowser/#/R-CFA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Canis familiaris 15377 R-CFA-193535 https://reactome.org/PathwayBrowser/#/R-CFA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Canis familiaris 15377 R-CFA-193709 https://reactome.org/PathwayBrowser/#/R-CFA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Canis familiaris 15377 R-CFA-193711 https://reactome.org/PathwayBrowser/#/R-CFA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 15377 R-CFA-193713 https://reactome.org/PathwayBrowser/#/R-CFA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Canis familiaris 15377 R-CFA-193719 https://reactome.org/PathwayBrowser/#/R-CFA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 15377 R-CFA-193727 https://reactome.org/PathwayBrowser/#/R-CFA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 15377 R-CFA-193737 https://reactome.org/PathwayBrowser/#/R-CFA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Canis familiaris 15377 R-CFA-193743 https://reactome.org/PathwayBrowser/#/R-CFA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 15377 R-CFA-193766 https://reactome.org/PathwayBrowser/#/R-CFA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 15377 R-CFA-193780 https://reactome.org/PathwayBrowser/#/R-CFA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Canis familiaris 15377 R-CFA-193787 https://reactome.org/PathwayBrowser/#/R-CFA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Canis familiaris 15377 R-CFA-193792 https://reactome.org/PathwayBrowser/#/R-CFA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Canis familiaris 15377 R-CFA-193845 https://reactome.org/PathwayBrowser/#/R-CFA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Canis familiaris 15377 R-CFA-193964 https://reactome.org/PathwayBrowser/#/R-CFA-193964 CYP21A2 21-hydroxylates PROG IEA Canis familiaris 15377 R-CFA-193965 https://reactome.org/PathwayBrowser/#/R-CFA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Canis familiaris 15377 R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 15377 R-CFA-193995 https://reactome.org/PathwayBrowser/#/R-CFA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Canis familiaris 15377 R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 15377 R-CFA-194017 https://reactome.org/PathwayBrowser/#/R-CFA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Canis familiaris 15377 R-CFA-194641 https://reactome.org/PathwayBrowser/#/R-CFA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15377 R-CFA-194669 https://reactome.org/PathwayBrowser/#/R-CFA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15377 R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 15377 R-CFA-195664 https://reactome.org/PathwayBrowser/#/R-CFA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Canis familiaris 15377 R-CFA-196950 https://reactome.org/PathwayBrowser/#/R-CFA-196950 2xTRAP hydrolyzes FMN to RIB IEA Canis familiaris 15377 R-CFA-196955 https://reactome.org/PathwayBrowser/#/R-CFA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Canis familiaris 15377 R-CFA-197271 https://reactome.org/PathwayBrowser/#/R-CFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Canis familiaris 15377 R-CFA-199456 https://reactome.org/PathwayBrowser/#/R-CFA-199456 PTEN dephosphorylates PIP3 IEA Canis familiaris 15377 R-CFA-199959 https://reactome.org/PathwayBrowser/#/R-CFA-199959 ERKs are inactivated by protein phosphatase 2A IEA Canis familiaris 15377 R-CFA-2002466 https://reactome.org/PathwayBrowser/#/R-CFA-2002466 Formation of allysine by LOX IEA Canis familiaris 15377 R-CFA-200661 https://reactome.org/PathwayBrowser/#/R-CFA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Canis familiaris 15377 R-CFA-200740 https://reactome.org/PathwayBrowser/#/R-CFA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Canis familiaris 15377 R-CFA-201035 https://reactome.org/PathwayBrowser/#/R-CFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Canis familiaris 15377 R-CFA-201790 https://reactome.org/PathwayBrowser/#/R-CFA-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Canis familiaris 15377 R-CFA-202214 https://reactome.org/PathwayBrowser/#/R-CFA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Canis familiaris 15377 R-CFA-2022368 https://reactome.org/PathwayBrowser/#/R-CFA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Canis familiaris 15377 R-CFA-202237 https://reactome.org/PathwayBrowser/#/R-CFA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Canis familiaris 15377 R-CFA-2022378 https://reactome.org/PathwayBrowser/#/R-CFA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Canis familiaris 15377 R-CFA-2022379 https://reactome.org/PathwayBrowser/#/R-CFA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Canis familiaris 15377 R-CFA-2022381 https://reactome.org/PathwayBrowser/#/R-CFA-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 15377 R-CFA-2022383 https://reactome.org/PathwayBrowser/#/R-CFA-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 15377 R-CFA-2022396 https://reactome.org/PathwayBrowser/#/R-CFA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Canis familiaris 15377 R-CFA-2022398 https://reactome.org/PathwayBrowser/#/R-CFA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Canis familiaris 15377 R-CFA-2022399 https://reactome.org/PathwayBrowser/#/R-CFA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Canis familiaris 15377 R-CFA-2022403 https://reactome.org/PathwayBrowser/#/R-CFA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Canis familiaris 15377 R-CFA-2022405 https://reactome.org/PathwayBrowser/#/R-CFA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 15377 R-CFA-2022411 https://reactome.org/PathwayBrowser/#/R-CFA-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 15377 R-CFA-2022412 https://reactome.org/PathwayBrowser/#/R-CFA-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Canis familiaris 15377 R-CFA-2022887 https://reactome.org/PathwayBrowser/#/R-CFA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Canis familiaris 15377 R-CFA-2023971 https://reactome.org/PathwayBrowser/#/R-CFA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 15377 R-CFA-2023973 https://reactome.org/PathwayBrowser/#/R-CFA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 15377 R-CFA-202407 https://reactome.org/PathwayBrowser/#/R-CFA-202407 PLC-gamma1 hydrolyses PIP2 IEA Canis familiaris 15377 R-CFA-2028294 https://reactome.org/PathwayBrowser/#/R-CFA-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Canis familiaris 15377 R-CFA-2029468 https://reactome.org/PathwayBrowser/#/R-CFA-2029468 Conversion of PA into DAG by PAP-1 IEA Canis familiaris 15377 R-CFA-2029471 https://reactome.org/PathwayBrowser/#/R-CFA-2029471 Hydrolysis of PC to PA by PLD IEA Canis familiaris 15377 R-CFA-2029475 https://reactome.org/PathwayBrowser/#/R-CFA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Canis familiaris 15377 R-CFA-203797 https://reactome.org/PathwayBrowser/#/R-CFA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Canis familiaris 15377 R-CFA-204169 https://reactome.org/PathwayBrowser/#/R-CFA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Canis familiaris 15377 R-CFA-2046083 https://reactome.org/PathwayBrowser/#/R-CFA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Canis familiaris 15377 R-CFA-2046084 https://reactome.org/PathwayBrowser/#/R-CFA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Canis familiaris 15377 R-CFA-2046088 https://reactome.org/PathwayBrowser/#/R-CFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Canis familiaris 15377 R-CFA-2046089 https://reactome.org/PathwayBrowser/#/R-CFA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Canis familiaris 15377 R-CFA-2046090 https://reactome.org/PathwayBrowser/#/R-CFA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 15377 R-CFA-2046092 https://reactome.org/PathwayBrowser/#/R-CFA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Canis familiaris 15377 R-CFA-2046094 https://reactome.org/PathwayBrowser/#/R-CFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Canis familiaris 15377 R-CFA-2046095 https://reactome.org/PathwayBrowser/#/R-CFA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Canis familiaris 15377 R-CFA-2046096 https://reactome.org/PathwayBrowser/#/R-CFA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Canis familiaris 15377 R-CFA-2046097 https://reactome.org/PathwayBrowser/#/R-CFA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 15377 R-CFA-2046100 https://reactome.org/PathwayBrowser/#/R-CFA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Canis familiaris 15377 R-CFA-204662 https://reactome.org/PathwayBrowser/#/R-CFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Canis familiaris 15377 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 15377 R-CFA-2065357 https://reactome.org/PathwayBrowser/#/R-CFA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Canis familiaris 15377 R-CFA-2066778 https://reactome.org/PathwayBrowser/#/R-CFA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Canis familiaris 15377 R-CFA-2066779 https://reactome.org/PathwayBrowser/#/R-CFA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Canis familiaris 15377 R-CFA-2090037 https://reactome.org/PathwayBrowser/#/R-CFA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Canis familiaris 15377 R-CFA-2090038 https://reactome.org/PathwayBrowser/#/R-CFA-2090038 NAGLU hydrolyses heparan chain(2) IEA Canis familiaris 15377 R-CFA-2090043 https://reactome.org/PathwayBrowser/#/R-CFA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Canis familiaris 15377 R-CFA-2090079 https://reactome.org/PathwayBrowser/#/R-CFA-2090079 GLB1 hydrolyses linker chain(2) IEA Canis familiaris 15377 R-CFA-209055 https://reactome.org/PathwayBrowser/#/R-CFA-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Canis familiaris 15377 R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 15377 R-CFA-209845 https://reactome.org/PathwayBrowser/#/R-CFA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Canis familiaris 15377 R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 15377 R-CFA-209891 https://reactome.org/PathwayBrowser/#/R-CFA-209891 Dopamine is oxidised to noradrenaline IEA Canis familiaris 15377 R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 15377 R-CFA-2105001 https://reactome.org/PathwayBrowser/#/R-CFA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Canis familiaris 15377 R-CFA-211873 https://reactome.org/PathwayBrowser/#/R-CFA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Canis familiaris 15377 R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 15377 R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 15377 R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 15377 R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 15377 R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 15377 R-CFA-211923 https://reactome.org/PathwayBrowser/#/R-CFA-211923 CYP26C1 4-hydroxylates 9cRA IEA Canis familiaris 15377 R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 15377 R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 15377 R-CFA-211950 https://reactome.org/PathwayBrowser/#/R-CFA-211950 CYP24A1 24-hydroxylates CTL IEA Canis familiaris 15377 R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 15377 R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 15377 R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 15377 R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 15377 R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 15377 R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 15377 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 15377 R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 15377 R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 15377 R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 15377 R-CFA-2130725 https://reactome.org/PathwayBrowser/#/R-CFA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Canis familiaris 15377 R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 15377 R-CFA-2160492 https://reactome.org/PathwayBrowser/#/R-CFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Canis familiaris 15377 R-CFA-2160874 https://reactome.org/PathwayBrowser/#/R-CFA-2160874 HYAL1 hydrolyses (HA)50 IEA Canis familiaris 15377 R-CFA-2161187 https://reactome.org/PathwayBrowser/#/R-CFA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Canis familiaris 15377 R-CFA-2161195 https://reactome.org/PathwayBrowser/#/R-CFA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Canis familiaris 15377 R-CFA-2161745 https://reactome.org/PathwayBrowser/#/R-CFA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15377 R-CFA-2161791 https://reactome.org/PathwayBrowser/#/R-CFA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Canis familiaris 15377 R-CFA-2161792 https://reactome.org/PathwayBrowser/#/R-CFA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15377 R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Canis familiaris 15377 R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 15377 R-CFA-2161890 https://reactome.org/PathwayBrowser/#/R-CFA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Canis familiaris 15377 R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Canis familiaris 15377 R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 15377 R-CFA-2161951 https://reactome.org/PathwayBrowser/#/R-CFA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Canis familiaris 15377 R-CFA-2161959 https://reactome.org/PathwayBrowser/#/R-CFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Canis familiaris 15377 R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Canis familiaris 15377 R-CFA-2161999 https://reactome.org/PathwayBrowser/#/R-CFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Canis familiaris 15377 R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 15377 R-CFA-2162225 https://reactome.org/PathwayBrowser/#/R-CFA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Canis familiaris 15377 R-CFA-2162226 https://reactome.org/PathwayBrowser/#/R-CFA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Canis familiaris 15377 R-CFA-2162227 https://reactome.org/PathwayBrowser/#/R-CFA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Canis familiaris 15377 R-CFA-216723 https://reactome.org/PathwayBrowser/#/R-CFA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Canis familiaris 15377 R-CFA-216757 https://reactome.org/PathwayBrowser/#/R-CFA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Canis familiaris 15377 R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 15377 R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 15377 R-CFA-2187401 https://reactome.org/PathwayBrowser/#/R-CFA-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Canis familiaris 15377 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 15377 R-CFA-2393939 https://reactome.org/PathwayBrowser/#/R-CFA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 15377 R-CFA-2393954 https://reactome.org/PathwayBrowser/#/R-CFA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 15377 R-CFA-2395340 https://reactome.org/PathwayBrowser/#/R-CFA-2395340 Formation of hydroxyallysine by LOX IEA Canis familiaris 15377 R-CFA-2395818 https://reactome.org/PathwayBrowser/#/R-CFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Canis familiaris 15377 R-CFA-2395849 https://reactome.org/PathwayBrowser/#/R-CFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 15377 R-CFA-2395869 https://reactome.org/PathwayBrowser/#/R-CFA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 15377 R-CFA-2395872 https://reactome.org/PathwayBrowser/#/R-CFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Canis familiaris 15377 R-CFA-2395873 https://reactome.org/PathwayBrowser/#/R-CFA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Canis familiaris 15377 R-CFA-2395876 https://reactome.org/PathwayBrowser/#/R-CFA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 15377 R-CFA-2395879 https://reactome.org/PathwayBrowser/#/R-CFA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 15377 R-CFA-2395965 https://reactome.org/PathwayBrowser/#/R-CFA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Canis familiaris 15377 R-CFA-2408551 https://reactome.org/PathwayBrowser/#/R-CFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Canis familiaris 15377 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 15377 R-CFA-2454118 https://reactome.org/PathwayBrowser/#/R-CFA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Canis familiaris 15377 R-CFA-2465924 https://reactome.org/PathwayBrowser/#/R-CFA-2465924 OPN1LW binds 11cRAL IEA Canis familiaris 15377 R-CFA-2466085 https://reactome.org/PathwayBrowser/#/R-CFA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Canis familiaris 15377 R-CFA-2509793 https://reactome.org/PathwayBrowser/#/R-CFA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Canis familiaris 15377 R-CFA-2509816 https://reactome.org/PathwayBrowser/#/R-CFA-2509816 NUDT16 hydrolyses IDP to IMP IEA Canis familiaris 15377 R-CFA-2509827 https://reactome.org/PathwayBrowser/#/R-CFA-2509827 ITPA hydrolyses ITP to IMP IEA Canis familiaris 15377 R-CFA-2509831 https://reactome.org/PathwayBrowser/#/R-CFA-2509831 ITPA hydrolyses XTP to XMP IEA Canis familiaris 15377 R-CFA-2509838 https://reactome.org/PathwayBrowser/#/R-CFA-2509838 ITPA hydrolyses dITP to dIMP IEA Canis familiaris 15377 R-CFA-2529015 https://reactome.org/PathwayBrowser/#/R-CFA-2529015 Dephosphorylation of CK2-modified condensin I IEA Canis familiaris 15377 R-CFA-2584246 https://reactome.org/PathwayBrowser/#/R-CFA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Canis familiaris 15377 R-CFA-2632521 https://reactome.org/PathwayBrowser/#/R-CFA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Canis familiaris 15377 R-CFA-265783 https://reactome.org/PathwayBrowser/#/R-CFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Canis familiaris 15377 R-CFA-266012 https://reactome.org/PathwayBrowser/#/R-CFA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Canis familiaris 15377 R-CFA-266046 https://reactome.org/PathwayBrowser/#/R-CFA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Canis familiaris 15377 R-CFA-266051 https://reactome.org/PathwayBrowser/#/R-CFA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Canis familiaris 15377 R-CFA-266072 https://reactome.org/PathwayBrowser/#/R-CFA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Canis familiaris 15377 R-CFA-266082 https://reactome.org/PathwayBrowser/#/R-CFA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Canis familiaris 15377 R-CFA-2730847 https://reactome.org/PathwayBrowser/#/R-CFA-2730847 Hydrolysis of PIP2 by PLCG IEA Canis familiaris 15377 R-CFA-2730849 https://reactome.org/PathwayBrowser/#/R-CFA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Canis familiaris 15377 R-CFA-2855047 https://reactome.org/PathwayBrowser/#/R-CFA-2855047 Hydrolysis of internal thioester in C4b IEA Canis familiaris 15377 R-CFA-2995330 https://reactome.org/PathwayBrowser/#/R-CFA-2995330 COX10 transforms heme to heme O IEA Canis familiaris 15377 R-CFA-2995334 https://reactome.org/PathwayBrowser/#/R-CFA-2995334 COX15 transforms heme O to heme A IEA Canis familiaris 15377 R-CFA-2995388 https://reactome.org/PathwayBrowser/#/R-CFA-2995388 PP2A dephosphorylates BANF1 IEA Canis familiaris 15377 R-CFA-3002811 https://reactome.org/PathwayBrowser/#/R-CFA-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Canis familiaris 15377 R-CFA-3095901 https://reactome.org/PathwayBrowser/#/R-CFA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Canis familiaris 15377 R-CFA-3215295 https://reactome.org/PathwayBrowser/#/R-CFA-3215295 USP7 deubiquitinates MDM2 IEA Canis familiaris 15377 R-CFA-3215310 https://reactome.org/PathwayBrowser/#/R-CFA-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Canis familiaris 15377 R-CFA-3247569 https://reactome.org/PathwayBrowser/#/R-CFA-3247569 PADI4 deiminates Histones IEA Canis familiaris 15377 R-CFA-3262512 https://reactome.org/PathwayBrowser/#/R-CFA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Canis familiaris 15377 R-CFA-3266566 https://reactome.org/PathwayBrowser/#/R-CFA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Canis familiaris 15377 R-CFA-3323013 https://reactome.org/PathwayBrowser/#/R-CFA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 15377 R-CFA-3341277 https://reactome.org/PathwayBrowser/#/R-CFA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 15377 R-CFA-3341296 https://reactome.org/PathwayBrowser/#/R-CFA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Canis familiaris 15377 R-CFA-3341343 https://reactome.org/PathwayBrowser/#/R-CFA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Canis familiaris 15377 R-CFA-3343700 https://reactome.org/PathwayBrowser/#/R-CFA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 15377 R-CFA-3371467 https://reactome.org/PathwayBrowser/#/R-CFA-3371467 SIRT1 deacetylates HSF1 IEA Canis familiaris 15377 R-CFA-350604 https://reactome.org/PathwayBrowser/#/R-CFA-350604 Agmatine + H2O <=> putrescine + urea IEA Canis familiaris 15377 R-CFA-350901 https://reactome.org/PathwayBrowser/#/R-CFA-350901 Iodide is organified IEA Canis familiaris 15377 R-CFA-3640872 https://reactome.org/PathwayBrowser/#/R-CFA-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Canis familiaris 15377 R-CFA-3697882 https://reactome.org/PathwayBrowser/#/R-CFA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Canis familiaris 15377 R-CFA-374909 https://reactome.org/PathwayBrowser/#/R-CFA-374909 Catabolism of Noradrenaline IEA Canis familiaris 15377 R-CFA-3769447 https://reactome.org/PathwayBrowser/#/R-CFA-3769447 HDAC1:2-containing complex deacetylate histones IEA Canis familiaris 15377 R-CFA-377643 https://reactome.org/PathwayBrowser/#/R-CFA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Canis familiaris 15377 R-CFA-3777129 https://reactome.org/PathwayBrowser/#/R-CFA-3777129 HDAC3 containing complexes deacetylate histone IEA Canis familiaris 15377 R-CFA-3781011 https://reactome.org/PathwayBrowser/#/R-CFA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Canis familiaris 15377 R-CFA-3781018 https://reactome.org/PathwayBrowser/#/R-CFA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Canis familiaris 15377 R-CFA-3782637 https://reactome.org/PathwayBrowser/#/R-CFA-3782637 HDAC8 deacetylates histones IEA Canis familiaris 15377 R-CFA-3782655 https://reactome.org/PathwayBrowser/#/R-CFA-3782655 HDAC10 deacetylates histone IEA Canis familiaris 15377 R-CFA-379382 https://reactome.org/PathwayBrowser/#/R-CFA-379382 MAOA:FAD deaminates DA to DOPAC IEA Canis familiaris 15377 R-CFA-379395 https://reactome.org/PathwayBrowser/#/R-CFA-379395 MAOA:FAD deaminates 3MT to HVA IEA Canis familiaris 15377 R-CFA-380949 https://reactome.org/PathwayBrowser/#/R-CFA-380949 AMPK is dephosphorylated IEA Canis familiaris 15377 R-CFA-382553 https://reactome.org/PathwayBrowser/#/R-CFA-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Canis familiaris 15377 R-CFA-382560 https://reactome.org/PathwayBrowser/#/R-CFA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Canis familiaris 15377 R-CFA-382575 https://reactome.org/PathwayBrowser/#/R-CFA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Canis familiaris 15377 R-CFA-383190 https://reactome.org/PathwayBrowser/#/R-CFA-383190 HCO3- transport through ion channel IEA Canis familiaris 15377 R-CFA-389821 https://reactome.org/PathwayBrowser/#/R-CFA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Canis familiaris 15377 R-CFA-389862 https://reactome.org/PathwayBrowser/#/R-CFA-389862 Conversion of glyoxylate to oxalate IEA Canis familiaris 15377 R-CFA-389986 https://reactome.org/PathwayBrowser/#/R-CFA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Canis familiaris 15377 R-CFA-390252 https://reactome.org/PathwayBrowser/#/R-CFA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Canis familiaris 15377 R-CFA-390304 https://reactome.org/PathwayBrowser/#/R-CFA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Canis familiaris 15377 R-CFA-399998 https://reactome.org/PathwayBrowser/#/R-CFA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Canis familiaris 15377 R-CFA-4084976 https://reactome.org/PathwayBrowser/#/R-CFA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Canis familiaris 15377 R-CFA-4084989 https://reactome.org/PathwayBrowser/#/R-CFA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Canis familiaris 15377 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 15377 R-CFA-4084999 https://reactome.org/PathwayBrowser/#/R-CFA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 15377 R-CFA-4085021 https://reactome.org/PathwayBrowser/#/R-CFA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Canis familiaris 15377 R-CFA-4085029 https://reactome.org/PathwayBrowser/#/R-CFA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 15377 R-CFA-4086392 https://reactome.org/PathwayBrowser/#/R-CFA-4086392 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 15377 R-CFA-4088141 https://reactome.org/PathwayBrowser/#/R-CFA-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Canis familiaris 15377 R-CFA-4093339 https://reactome.org/PathwayBrowser/#/R-CFA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Canis familiaris 15377 R-CFA-416559 https://reactome.org/PathwayBrowser/#/R-CFA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Canis familiaris 15377 R-CFA-418553 https://reactome.org/PathwayBrowser/#/R-CFA-418553 cAMP degradation by Phosphodiesterases IEA Canis familiaris 15377 R-CFA-426043 https://reactome.org/PathwayBrowser/#/R-CFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Canis familiaris 15377 R-CFA-428205 https://reactome.org/PathwayBrowser/#/R-CFA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Canis familiaris 15377 R-CFA-428231 https://reactome.org/PathwayBrowser/#/R-CFA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Canis familiaris 15377 R-CFA-428259 https://reactome.org/PathwayBrowser/#/R-CFA-428259 DEGS1 dehydrogenates dihydroceramide IEA Canis familiaris 15377 R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 15377 R-CFA-428262 https://reactome.org/PathwayBrowser/#/R-CFA-428262 ACER3 hydrolyzes phytoceramide IEA Canis familiaris 15377 R-CFA-428664 https://reactome.org/PathwayBrowser/#/R-CFA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Canis familiaris 15377 R-CFA-428690 https://reactome.org/PathwayBrowser/#/R-CFA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Canis familiaris 15377 R-CFA-428696 https://reactome.org/PathwayBrowser/#/R-CFA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Canis familiaris 15377 R-CFA-429157 https://reactome.org/PathwayBrowser/#/R-CFA-429157 ABCC4 accumulation of dense granule contents IEA Canis familiaris 15377 R-CFA-429860 https://reactome.org/PathwayBrowser/#/R-CFA-429860 DCP1-DCP2 complex decaps mRNA IEA Canis familiaris 15377 R-CFA-429955 https://reactome.org/PathwayBrowser/#/R-CFA-429955 CCR4-NOT complex deadenylates mRNA IEA Canis familiaris 15377 R-CFA-429961 https://reactome.org/PathwayBrowser/#/R-CFA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Canis familiaris 15377 R-CFA-429992 https://reactome.org/PathwayBrowser/#/R-CFA-429992 PARN deadenylates mRNA IEA Canis familiaris 15377 R-CFA-430021 https://reactome.org/PathwayBrowser/#/R-CFA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Canis familiaris 15377 R-CFA-430028 https://reactome.org/PathwayBrowser/#/R-CFA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Canis familiaris 15377 R-CFA-432010 https://reactome.org/PathwayBrowser/#/R-CFA-432010 Aquaporin-1 passively transports water into cell IEA Canis familiaris 15377 R-CFA-432054 https://reactome.org/PathwayBrowser/#/R-CFA-432054 Aquaporin-1 passively transports water out of cell IEA Canis familiaris 15377 R-CFA-432065 https://reactome.org/PathwayBrowser/#/R-CFA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Canis familiaris 15377 R-CFA-432067 https://reactome.org/PathwayBrowser/#/R-CFA-432067 Aquaporin-4 passively transports water out of cell IEA Canis familiaris 15377 R-CFA-4419948 https://reactome.org/PathwayBrowser/#/R-CFA-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Canis familiaris 15377 R-CFA-445714 https://reactome.org/PathwayBrowser/#/R-CFA-445714 Aquaporin-3 passively transports water out of cell IEA Canis familiaris 15377 R-CFA-446200 https://reactome.org/PathwayBrowser/#/R-CFA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Canis familiaris 15377 R-CFA-449937 https://reactome.org/PathwayBrowser/#/R-CFA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Canis familiaris 15377 R-CFA-452036 https://reactome.org/PathwayBrowser/#/R-CFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Canis familiaris 15377 R-CFA-4551451 https://reactome.org/PathwayBrowser/#/R-CFA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Canis familiaris 15377 R-CFA-504054 https://reactome.org/PathwayBrowser/#/R-CFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Canis familiaris 15377 R-CFA-507868 https://reactome.org/PathwayBrowser/#/R-CFA-507868 Aquaporins passively transport water into cells IEA Canis familiaris 15377 R-CFA-507870 https://reactome.org/PathwayBrowser/#/R-CFA-507870 Aquaporins passively transport water out of cells IEA Canis familiaris 15377 R-CFA-508308 https://reactome.org/PathwayBrowser/#/R-CFA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Canis familiaris 15377 R-CFA-5221130 https://reactome.org/PathwayBrowser/#/R-CFA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Canis familiaris 15377 R-CFA-5223313 https://reactome.org/PathwayBrowser/#/R-CFA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Canis familiaris 15377 R-CFA-5223317 https://reactome.org/PathwayBrowser/#/R-CFA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Canis familiaris 15377 R-CFA-5251955 https://reactome.org/PathwayBrowser/#/R-CFA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Canis familiaris 15377 R-CFA-5251959 https://reactome.org/PathwayBrowser/#/R-CFA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Canis familiaris 15377 R-CFA-5251989 https://reactome.org/PathwayBrowser/#/R-CFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Canis familiaris 15377 R-CFA-5362459 https://reactome.org/PathwayBrowser/#/R-CFA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Canis familiaris 15377 R-CFA-5362522 https://reactome.org/PathwayBrowser/#/R-CFA-5362522 ALDHs oxidise atRAL to atRA IEA Canis familiaris 15377 R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 15377 R-CFA-5423647 https://reactome.org/PathwayBrowser/#/R-CFA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Canis familiaris 15377 R-CFA-5423664 https://reactome.org/PathwayBrowser/#/R-CFA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Canis familiaris 15377 R-CFA-5423672 https://reactome.org/PathwayBrowser/#/R-CFA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Canis familiaris 15377 R-CFA-5433072 https://reactome.org/PathwayBrowser/#/R-CFA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Canis familiaris 15377 R-CFA-5433074 https://reactome.org/PathwayBrowser/#/R-CFA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Canis familiaris 15377 R-CFA-548843 https://reactome.org/PathwayBrowser/#/R-CFA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Canis familiaris 15377 R-CFA-5602295 https://reactome.org/PathwayBrowser/#/R-CFA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Canis familiaris 15377 R-CFA-5603114 https://reactome.org/PathwayBrowser/#/R-CFA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Canis familiaris 15377 R-CFA-5607735 https://reactome.org/PathwayBrowser/#/R-CFA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Canis familiaris 15377 R-CFA-5623513 https://reactome.org/PathwayBrowser/#/R-CFA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Canis familiaris 15377 R-CFA-5628905 https://reactome.org/PathwayBrowser/#/R-CFA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Canis familiaris 15377 R-CFA-5631885 https://reactome.org/PathwayBrowser/#/R-CFA-5631885 PRDX1 overoxidizes IEA Canis familiaris 15377 R-CFA-5649705 https://reactome.org/PathwayBrowser/#/R-CFA-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Canis familiaris 15377 R-CFA-5653770 https://reactome.org/PathwayBrowser/#/R-CFA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Canis familiaris 15377 R-CFA-5653786 https://reactome.org/PathwayBrowser/#/R-CFA-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Canis familiaris 15377 R-CFA-5659861 https://reactome.org/PathwayBrowser/#/R-CFA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Canis familiaris 15377 R-CFA-5662692 https://reactome.org/PathwayBrowser/#/R-CFA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Canis familiaris 15377 R-CFA-5665809 https://reactome.org/PathwayBrowser/#/R-CFA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Canis familiaris 15377 R-CFA-5675373 https://reactome.org/PathwayBrowser/#/R-CFA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Canis familiaris 15377 R-CFA-5675376 https://reactome.org/PathwayBrowser/#/R-CFA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Canis familiaris 15377 R-CFA-5675431 https://reactome.org/PathwayBrowser/#/R-CFA-5675431 PP2A dephosphorylates RAF1 IEA Canis familiaris 15377 R-CFA-5675433 https://reactome.org/PathwayBrowser/#/R-CFA-5675433 PP5 dephosphorylates RAF1 S338 IEA Canis familiaris 15377 R-CFA-5676637 https://reactome.org/PathwayBrowser/#/R-CFA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Canis familiaris 15377 R-CFA-5678327 https://reactome.org/PathwayBrowser/#/R-CFA-5678327 MIOX oxidises Ins to GlcA IEA Canis familiaris 15377 R-CFA-5678706 https://reactome.org/PathwayBrowser/#/R-CFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Canis familiaris 15377 R-CFA-5678863 https://reactome.org/PathwayBrowser/#/R-CFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Canis familiaris 15377 R-CFA-5679041 https://reactome.org/PathwayBrowser/#/R-CFA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 15377 R-CFA-5682285 https://reactome.org/PathwayBrowser/#/R-CFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Canis familiaris 15377 R-CFA-5683405 https://reactome.org/PathwayBrowser/#/R-CFA-5683405 PPP5C dephosphorylates TP53BP1 IEA Canis familiaris 15377 R-CFA-5683714 https://reactome.org/PathwayBrowser/#/R-CFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Canis familiaris 15377 R-CFA-5683967 https://reactome.org/PathwayBrowser/#/R-CFA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Canis familiaris 15377 R-CFA-5684864 https://reactome.org/PathwayBrowser/#/R-CFA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Canis familiaris 15377 R-CFA-5685902 https://reactome.org/PathwayBrowser/#/R-CFA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Canis familiaris 15377 R-CFA-5685994 https://reactome.org/PathwayBrowser/#/R-CFA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Canis familiaris 15377 R-CFA-5687464 https://reactome.org/PathwayBrowser/#/R-CFA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Canis familiaris 15377 R-CFA-5687664 https://reactome.org/PathwayBrowser/#/R-CFA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Canis familiaris 15377 R-CFA-5687758 https://reactome.org/PathwayBrowser/#/R-CFA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Canis familiaris 15377 R-CFA-5688797 https://reactome.org/PathwayBrowser/#/R-CFA-5688797 ATXN3 family cleave Ub chains IEA Canis familiaris 15377 R-CFA-5688837 https://reactome.org/PathwayBrowser/#/R-CFA-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Canis familiaris 15377 R-CFA-5689000 https://reactome.org/PathwayBrowser/#/R-CFA-5689000 AADAC deacetylates PHEN IEA Canis familiaris 15377 R-CFA-5689950 https://reactome.org/PathwayBrowser/#/R-CFA-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Canis familiaris 15377 R-CFA-5689972 https://reactome.org/PathwayBrowser/#/R-CFA-5689972 USP2 deubiquitinates MDM2,MDM4 IEA Canis familiaris 15377 R-CFA-5689973 https://reactome.org/PathwayBrowser/#/R-CFA-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Canis familiaris 15377 R-CFA-5690042 https://reactome.org/PathwayBrowser/#/R-CFA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 15377 R-CFA-5690043 https://reactome.org/PathwayBrowser/#/R-CFA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 15377 R-CFA-5690046 https://reactome.org/PathwayBrowser/#/R-CFA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Canis familiaris 15377 R-CFA-5690066 https://reactome.org/PathwayBrowser/#/R-CFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 15377 R-CFA-5690080 https://reactome.org/PathwayBrowser/#/R-CFA-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Canis familiaris 15377 R-CFA-5690152 https://reactome.org/PathwayBrowser/#/R-CFA-5690152 USP5 cleaves polyubiquitin IEA Canis familiaris 15377 R-CFA-5690157 https://reactome.org/PathwayBrowser/#/R-CFA-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Canis familiaris 15377 R-CFA-5690159 https://reactome.org/PathwayBrowser/#/R-CFA-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Canis familiaris 15377 R-CFA-5690196 https://reactome.org/PathwayBrowser/#/R-CFA-5690196 USP8 deubiquitinates RNF128 IEA Canis familiaris 15377 R-CFA-5690319 https://reactome.org/PathwayBrowser/#/R-CFA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Canis familiaris 15377 R-CFA-5690517 https://reactome.org/PathwayBrowser/#/R-CFA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Canis familiaris 15377 R-CFA-5690565 https://reactome.org/PathwayBrowser/#/R-CFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15377 R-CFA-5690759 https://reactome.org/PathwayBrowser/#/R-CFA-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Canis familiaris 15377 R-CFA-5690790 https://reactome.org/PathwayBrowser/#/R-CFA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Canis familiaris 15377 R-CFA-5690808 https://reactome.org/PathwayBrowser/#/R-CFA-5690808 UCHL3, SENP8 cleave NEDD8 IEA Canis familiaris 15377 R-CFA-5690856 https://reactome.org/PathwayBrowser/#/R-CFA-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Canis familiaris 15377 R-CFA-5690870 https://reactome.org/PathwayBrowser/#/R-CFA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Canis familiaris 15377 R-CFA-5691381 https://reactome.org/PathwayBrowser/#/R-CFA-5691381 MYSM1 deubiquitinates Histone H2A IEA Canis familiaris 15377 R-CFA-5691411 https://reactome.org/PathwayBrowser/#/R-CFA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Canis familiaris 15377 R-CFA-5691439 https://reactome.org/PathwayBrowser/#/R-CFA-5691439 BRISC complex deubiquitinates NLRP3 IEA Canis familiaris 15377 R-CFA-5691507 https://reactome.org/PathwayBrowser/#/R-CFA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Canis familiaris 15377 R-CFA-5691512 https://reactome.org/PathwayBrowser/#/R-CFA-5691512 APEH hydrolyses NAc-Ser-protein IEA Canis familiaris 15377 R-CFA-5692261 https://reactome.org/PathwayBrowser/#/R-CFA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Canis familiaris 15377 R-CFA-5692283 https://reactome.org/PathwayBrowser/#/R-CFA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Canis familiaris 15377 R-CFA-5692462 https://reactome.org/PathwayBrowser/#/R-CFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Canis familiaris 15377 R-CFA-5692480 https://reactome.org/PathwayBrowser/#/R-CFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Canis familiaris 15377 R-CFA-5692754 https://reactome.org/PathwayBrowser/#/R-CFA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Canis familiaris 15377 R-CFA-5693153 https://reactome.org/PathwayBrowser/#/R-CFA-5693153 PPM1K dephosphorylates p-BCKDH IEA Canis familiaris 15377 R-CFA-5693373 https://reactome.org/PathwayBrowser/#/R-CFA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Canis familiaris 15377 R-CFA-5693608 https://reactome.org/PathwayBrowser/#/R-CFA-5693608 Initial resection of double-strand break ends IEA Canis familiaris 15377 R-CFA-5693691 https://reactome.org/PathwayBrowser/#/R-CFA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Canis familiaris 15377 R-CFA-5693724 https://reactome.org/PathwayBrowser/#/R-CFA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Canis familiaris 15377 R-CFA-5693742 https://reactome.org/PathwayBrowser/#/R-CFA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Canis familiaris 15377 R-CFA-5693761 https://reactome.org/PathwayBrowser/#/R-CFA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Canis familiaris 15377 R-CFA-5693807 https://reactome.org/PathwayBrowser/#/R-CFA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Canis familiaris 15377 R-CFA-5694077 https://reactome.org/PathwayBrowser/#/R-CFA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Canis familiaris 15377 R-CFA-5694109 https://reactome.org/PathwayBrowser/#/R-CFA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Canis familiaris 15377 R-CFA-5694126 https://reactome.org/PathwayBrowser/#/R-CFA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Canis familiaris 15377 R-CFA-5694137 https://reactome.org/PathwayBrowser/#/R-CFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Canis familiaris 15377 R-CFA-5694421 https://reactome.org/PathwayBrowser/#/R-CFA-5694421 PP6 dephosphorylates SEC24 IEA Canis familiaris 15377 R-CFA-5694462 https://reactome.org/PathwayBrowser/#/R-CFA-5694462 ABHD6,12 hydrolyse 3AG IEA Canis familiaris 15377 R-CFA-5694485 https://reactome.org/PathwayBrowser/#/R-CFA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Canis familiaris 15377 R-CFA-5694563 https://reactome.org/PathwayBrowser/#/R-CFA-5694563 ABHD10 hydrolyses MPAG IEA Canis familiaris 15377 R-CFA-5694583 https://reactome.org/PathwayBrowser/#/R-CFA-5694583 ABHD4 hydrolyses NAPE IEA Canis familiaris 15377 R-CFA-5695964 https://reactome.org/PathwayBrowser/#/R-CFA-5695964 ABHD14B hydrolyses PNPB IEA Canis familiaris 15377 R-CFA-5696049 https://reactome.org/PathwayBrowser/#/R-CFA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 15377 R-CFA-5696080 https://reactome.org/PathwayBrowser/#/R-CFA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Canis familiaris 15377 R-CFA-5696091 https://reactome.org/PathwayBrowser/#/R-CFA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Canis familiaris 15377 R-CFA-5696101 https://reactome.org/PathwayBrowser/#/R-CFA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Canis familiaris 15377 R-CFA-5696119 https://reactome.org/PathwayBrowser/#/R-CFA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Canis familiaris 15377 R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 15377 R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 15377 R-CFA-5696197 https://reactome.org/PathwayBrowser/#/R-CFA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Canis familiaris 15377 R-CFA-5696230 https://reactome.org/PathwayBrowser/#/R-CFA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Canis familiaris 15377 R-CFA-5696365 https://reactome.org/PathwayBrowser/#/R-CFA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Canis familiaris 15377 R-CFA-5696408 https://reactome.org/PathwayBrowser/#/R-CFA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Canis familiaris 15377 R-CFA-5696415 https://reactome.org/PathwayBrowser/#/R-CFA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Canis familiaris 15377 R-CFA-5696534 https://reactome.org/PathwayBrowser/#/R-CFA-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Canis familiaris 15377 R-CFA-5696600 https://reactome.org/PathwayBrowser/#/R-CFA-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Canis familiaris 15377 R-CFA-5696605 https://reactome.org/PathwayBrowser/#/R-CFA-5696605 USP12, USP26 deubiquitinate AR IEA Canis familiaris 15377 R-CFA-5696627 https://reactome.org/PathwayBrowser/#/R-CFA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Canis familiaris 15377 R-CFA-5696872 https://reactome.org/PathwayBrowser/#/R-CFA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Canis familiaris 15377 R-CFA-5696914 https://reactome.org/PathwayBrowser/#/R-CFA-5696914 USP28 deubiquitinates CLSPN and MYC IEA Canis familiaris 15377 R-CFA-5696945 https://reactome.org/PathwayBrowser/#/R-CFA-5696945 USP33 deubiquitinates CCP110,ARRB IEA Canis familiaris 15377 R-CFA-5696947 https://reactome.org/PathwayBrowser/#/R-CFA-5696947 USP47 deubiquitinates POLB IEA Canis familiaris 15377 R-CFA-5696958 https://reactome.org/PathwayBrowser/#/R-CFA-5696958 USP44 deubiquitinates CDC20 IEA Canis familiaris 15377 R-CFA-5696960 https://reactome.org/PathwayBrowser/#/R-CFA-5696960 USP49 deubiquitinates H2B IEA Canis familiaris 15377 R-CFA-5696968 https://reactome.org/PathwayBrowser/#/R-CFA-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Canis familiaris 15377 R-CFA-5697009 https://reactome.org/PathwayBrowser/#/R-CFA-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Canis familiaris 15377 R-CFA-6781764 https://reactome.org/PathwayBrowser/#/R-CFA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Canis familiaris 15377 R-CFA-6781779 https://reactome.org/PathwayBrowser/#/R-CFA-6781779 USP13 deubiquitinates BECN1,USP10 IEA Canis familiaris 15377 R-CFA-6781814 https://reactome.org/PathwayBrowser/#/R-CFA-6781814 USP19 deubiquitinates RNF123 IEA Canis familiaris 15377 R-CFA-6781897 https://reactome.org/PathwayBrowser/#/R-CFA-6781897 USP11 deubiquitinates NFKBIA IEA Canis familiaris 15377 R-CFA-6782069 https://reactome.org/PathwayBrowser/#/R-CFA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Canis familiaris 15377 R-CFA-6782106 https://reactome.org/PathwayBrowser/#/R-CFA-6782106 USP10 deubiquitinates SNX3, CFTR IEA Canis familiaris 15377 R-CFA-6782628 https://reactome.org/PathwayBrowser/#/R-CFA-6782628 USP8 deubiquitinates STAM2:HGS IEA Canis familiaris 15377 R-CFA-6782820 https://reactome.org/PathwayBrowser/#/R-CFA-6782820 USP17 deubiquitinates SUDS3 IEA Canis familiaris 15377 R-CFA-6783177 https://reactome.org/PathwayBrowser/#/R-CFA-6783177 USP21 deubiquitinates GATA3,IL33 IEA Canis familiaris 15377 R-CFA-6783221 https://reactome.org/PathwayBrowser/#/R-CFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Canis familiaris 15377 R-CFA-6784959 https://reactome.org/PathwayBrowser/#/R-CFA-6784959 BPHL hydrolyses VACV to ACV IEA Canis familiaris 15377 R-CFA-6786190 https://reactome.org/PathwayBrowser/#/R-CFA-6786190 CMBL hydrolyses OM to OLMS IEA Canis familiaris 15377 R-CFA-6786239 https://reactome.org/PathwayBrowser/#/R-CFA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Canis familiaris 15377 R-CFA-6786421 https://reactome.org/PathwayBrowser/#/R-CFA-6786421 CHIA hydrolyses chitin IEA Canis familiaris 15377 R-CFA-6786650 https://reactome.org/PathwayBrowser/#/R-CFA-6786650 DDHD1,2 hydrolyse PA IEA Canis familiaris 15377 R-CFA-6787632 https://reactome.org/PathwayBrowser/#/R-CFA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Canis familiaris 15377 R-CFA-6788295 https://reactome.org/PathwayBrowser/#/R-CFA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Canis familiaris 15377 R-CFA-6788912 https://reactome.org/PathwayBrowser/#/R-CFA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Canis familiaris 15377 R-CFA-6789031 https://reactome.org/PathwayBrowser/#/R-CFA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 15377 R-CFA-6789126 https://reactome.org/PathwayBrowser/#/R-CFA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 15377 R-CFA-6789310 https://reactome.org/PathwayBrowser/#/R-CFA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Canis familiaris 15377 R-CFA-6792445 https://reactome.org/PathwayBrowser/#/R-CFA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Canis familiaris 15377 R-CFA-6792863 https://reactome.org/PathwayBrowser/#/R-CFA-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Canis familiaris 15377 R-CFA-6797627 https://reactome.org/PathwayBrowser/#/R-CFA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Canis familiaris 15377 R-CFA-6797630 https://reactome.org/PathwayBrowser/#/R-CFA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Canis familiaris 15377 R-CFA-6797653 https://reactome.org/PathwayBrowser/#/R-CFA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Canis familiaris 15377 R-CFA-6797913 https://reactome.org/PathwayBrowser/#/R-CFA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Canis familiaris 15377 R-CFA-6797955 https://reactome.org/PathwayBrowser/#/R-CFA-6797955 ALDH7A1 oxidises BETALD to BET IEA Canis familiaris 15377 R-CFA-6799545 https://reactome.org/PathwayBrowser/#/R-CFA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Canis familiaris 15377 R-CFA-6799604 https://reactome.org/PathwayBrowser/#/R-CFA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Canis familiaris 15377 R-CFA-6799695 https://reactome.org/PathwayBrowser/#/R-CFA-6799695 GPX5,6 reduce H2O2 to H2O IEA Canis familiaris 15377 R-CFA-6799977 https://reactome.org/PathwayBrowser/#/R-CFA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Canis familiaris 15377 R-CFA-6800198 https://reactome.org/PathwayBrowser/#/R-CFA-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Canis familiaris 15377 R-CFA-6800200 https://reactome.org/PathwayBrowser/#/R-CFA-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Canis familiaris 15377 R-CFA-6800299 https://reactome.org/PathwayBrowser/#/R-CFA-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Canis familiaris 15377 R-CFA-6801462 https://reactome.org/PathwayBrowser/#/R-CFA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Canis familiaris 15377 R-CFA-6803545 https://reactome.org/PathwayBrowser/#/R-CFA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Canis familiaris 15377 R-CFA-6803789 https://reactome.org/PathwayBrowser/#/R-CFA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Canis familiaris 15377 R-CFA-6805650 https://reactome.org/PathwayBrowser/#/R-CFA-6805650 MTA2-NuRD complex deacetylates TP53 IEA Canis familiaris 15377 R-CFA-6807008 https://reactome.org/PathwayBrowser/#/R-CFA-6807008 PTPRJ dephosphorylates MET IEA Canis familiaris 15377 R-CFA-6807027 https://reactome.org/PathwayBrowser/#/R-CFA-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Canis familiaris 15377 R-CFA-6807053 https://reactome.org/PathwayBrowser/#/R-CFA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Canis familiaris 15377 R-CFA-6807118 https://reactome.org/PathwayBrowser/#/R-CFA-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Canis familiaris 15377 R-CFA-6807206 https://reactome.org/PathwayBrowser/#/R-CFA-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Canis familiaris 15377 R-CFA-6807214 https://reactome.org/PathwayBrowser/#/R-CFA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Canis familiaris 15377 R-CFA-6808464 https://reactome.org/PathwayBrowser/#/R-CFA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Canis familiaris 15377 R-CFA-6808487 https://reactome.org/PathwayBrowser/#/R-CFA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 15377 R-CFA-6808496 https://reactome.org/PathwayBrowser/#/R-CFA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 15377 R-CFA-6809263 https://reactome.org/PathwayBrowser/#/R-CFA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Canis familiaris 15377 R-CFA-6809287 https://reactome.org/PathwayBrowser/#/R-CFA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Canis familiaris 15377 R-CFA-6809320 https://reactome.org/PathwayBrowser/#/R-CFA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Canis familiaris 15377 R-CFA-6809325 https://reactome.org/PathwayBrowser/#/R-CFA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Canis familiaris 15377 R-CFA-6809720 https://reactome.org/PathwayBrowser/#/R-CFA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Canis familiaris 15377 R-CFA-6809777 https://reactome.org/PathwayBrowser/#/R-CFA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Canis familiaris 15377 R-CFA-6809778 https://reactome.org/PathwayBrowser/#/R-CFA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Canis familiaris 15377 R-CFA-6810076 https://reactome.org/PathwayBrowser/#/R-CFA-6810076 DDO oxidizes D-Asp to OA IEA Canis familiaris 15377 R-CFA-6810410 https://reactome.org/PathwayBrowser/#/R-CFA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Canis familiaris 15377 R-CFA-6810472 https://reactome.org/PathwayBrowser/#/R-CFA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Canis familiaris 15377 R-CFA-6810474 https://reactome.org/PathwayBrowser/#/R-CFA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Canis familiaris 15377 R-CFA-6813720 https://reactome.org/PathwayBrowser/#/R-CFA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Canis familiaris 15377 R-CFA-6813740 https://reactome.org/PathwayBrowser/#/R-CFA-6813740 GDE1 hydrolyzes GroPIns IEA Canis familiaris 15377 R-CFA-6813749 https://reactome.org/PathwayBrowser/#/R-CFA-6813749 ALDH1A1 oxidises GA to DGA IEA Canis familiaris 15377 R-CFA-6814254 https://reactome.org/PathwayBrowser/#/R-CFA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Canis familiaris 15377 R-CFA-6814797 https://reactome.org/PathwayBrowser/#/R-CFA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Canis familiaris 15377 R-CFA-69199 https://reactome.org/PathwayBrowser/#/R-CFA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Canis familiaris 15377 R-CFA-70262 https://reactome.org/PathwayBrowser/#/R-CFA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Canis familiaris 15377 R-CFA-70479 https://reactome.org/PathwayBrowser/#/R-CFA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Canis familiaris 15377 R-CFA-70494 https://reactome.org/PathwayBrowser/#/R-CFA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Canis familiaris 15377 R-CFA-70569 https://reactome.org/PathwayBrowser/#/R-CFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Canis familiaris 15377 R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Canis familiaris 15377 R-CFA-70599 https://reactome.org/PathwayBrowser/#/R-CFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Canis familiaris 15377 R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Canis familiaris 15377 R-CFA-70609 https://reactome.org/PathwayBrowser/#/R-CFA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Canis familiaris 15377 R-CFA-70679 https://reactome.org/PathwayBrowser/#/R-CFA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Canis familiaris 15377 R-CFA-70785 https://reactome.org/PathwayBrowser/#/R-CFA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Canis familiaris 15377 R-CFA-70870 https://reactome.org/PathwayBrowser/#/R-CFA-70870 ECHS1 hydrates methacrylyl-CoA IEA Canis familiaris 15377 R-CFA-70881 https://reactome.org/PathwayBrowser/#/R-CFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Canis familiaris 15377 R-CFA-70903 https://reactome.org/PathwayBrowser/#/R-CFA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Canis familiaris 15377 R-CFA-70906 https://reactome.org/PathwayBrowser/#/R-CFA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Canis familiaris 15377 R-CFA-70938 https://reactome.org/PathwayBrowser/#/R-CFA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Canis familiaris 15377 R-CFA-70940 https://reactome.org/PathwayBrowser/#/R-CFA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Canis familiaris 15377 R-CFA-70941 https://reactome.org/PathwayBrowser/#/R-CFA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Canis familiaris 15377 R-CFA-70975 https://reactome.org/PathwayBrowser/#/R-CFA-70975 CS acetylates OA to citrate IEA Canis familiaris 15377 R-CFA-70982 https://reactome.org/PathwayBrowser/#/R-CFA-70982 FH tetramer hydrates fumarate to L-malate IEA Canis familiaris 15377 R-CFA-71146 https://reactome.org/PathwayBrowser/#/R-CFA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Canis familiaris 15377 R-CFA-71181 https://reactome.org/PathwayBrowser/#/R-CFA-71181 FAH cleaves 4FAA IEA Canis familiaris 15377 R-CFA-71200 https://reactome.org/PathwayBrowser/#/R-CFA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Canis familiaris 15377 R-CFA-71217 https://reactome.org/PathwayBrowser/#/R-CFA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Canis familiaris 15377 R-CFA-71260 https://reactome.org/PathwayBrowser/#/R-CFA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Canis familiaris 15377 R-CFA-71296 https://reactome.org/PathwayBrowser/#/R-CFA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Canis familiaris 15377 R-CFA-71660 https://reactome.org/PathwayBrowser/#/R-CFA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Canis familiaris 15377 R-CFA-71676 https://reactome.org/PathwayBrowser/#/R-CFA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Canis familiaris 15377 R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 15377 R-CFA-71723 https://reactome.org/PathwayBrowser/#/R-CFA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Canis familiaris 15377 R-CFA-71732 https://reactome.org/PathwayBrowser/#/R-CFA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Canis familiaris 15377 R-CFA-71825 https://reactome.org/PathwayBrowser/#/R-CFA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Canis familiaris 15377 R-CFA-73571 https://reactome.org/PathwayBrowser/#/R-CFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Canis familiaris 15377 R-CFA-73577 https://reactome.org/PathwayBrowser/#/R-CFA-73577 CAD hexamer transforms L-Gln to CAP IEA Canis familiaris 15377 R-CFA-73589 https://reactome.org/PathwayBrowser/#/R-CFA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Canis familiaris 15377 R-CFA-73591 https://reactome.org/PathwayBrowser/#/R-CFA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Canis familiaris 15377 R-CFA-73596 https://reactome.org/PathwayBrowser/#/R-CFA-73596 dCMP + H2O => dUMP + NH4+ IEA Canis familiaris 15377 R-CFA-73608 https://reactome.org/PathwayBrowser/#/R-CFA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Canis familiaris 15377 R-CFA-73618 https://reactome.org/PathwayBrowser/#/R-CFA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Canis familiaris 15377 R-CFA-73620 https://reactome.org/PathwayBrowser/#/R-CFA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Canis familiaris 15377 R-CFA-73647 https://reactome.org/PathwayBrowser/#/R-CFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Canis familiaris 15377 R-CFA-73666 https://reactome.org/PathwayBrowser/#/R-CFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Canis familiaris 15377 R-CFA-73792 https://reactome.org/PathwayBrowser/#/R-CFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Canis familiaris 15377 R-CFA-73794 https://reactome.org/PathwayBrowser/#/R-CFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Canis familiaris 15377 R-CFA-73797 https://reactome.org/PathwayBrowser/#/R-CFA-73797 FAICAR => IMP + H2O IEA Canis familiaris 15377 R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 15377 R-CFA-73815 https://reactome.org/PathwayBrowser/#/R-CFA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Canis familiaris 15377 R-CFA-74059 https://reactome.org/PathwayBrowser/#/R-CFA-74059 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 15377 R-CFA-74241 https://reactome.org/PathwayBrowser/#/R-CFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Canis familiaris 15377 R-CFA-74247 https://reactome.org/PathwayBrowser/#/R-CFA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Canis familiaris 15377 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 15377 R-CFA-74255 https://reactome.org/PathwayBrowser/#/R-CFA-74255 Guanine + H2O => Xanthine + NH4+ IEA Canis familiaris 15377 R-CFA-74258 https://reactome.org/PathwayBrowser/#/R-CFA-74258 XDH oxidizes xanthine to form urate IEA Canis familiaris 15377 R-CFA-74733 https://reactome.org/PathwayBrowser/#/R-CFA-74733 Insulin receptor de-phosphorylation IEA Canis familiaris 15377 R-CFA-74948 https://reactome.org/PathwayBrowser/#/R-CFA-74948 PP2A dephosphorylates p-RHO to RHO IEA Canis familiaris 15377 R-CFA-75872 https://reactome.org/PathwayBrowser/#/R-CFA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Canis familiaris 15377 R-CFA-75899 https://reactome.org/PathwayBrowser/#/R-CFA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Canis familiaris 15377 R-CFA-76031 https://reactome.org/PathwayBrowser/#/R-CFA-76031 2 H2O2 => O2 + 2 H2O IEA Canis familiaris 15377 R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 15377 R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 15377 R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 15377 R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 15377 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 15377 R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 15377 R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 15377 R-CFA-76590 https://reactome.org/PathwayBrowser/#/R-CFA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Canis familiaris 15377 R-CFA-77256 https://reactome.org/PathwayBrowser/#/R-CFA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Canis familiaris 15377 R-CFA-77277 https://reactome.org/PathwayBrowser/#/R-CFA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Canis familiaris 15377 R-CFA-77301 https://reactome.org/PathwayBrowser/#/R-CFA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Canis familiaris 15377 R-CFA-77314 https://reactome.org/PathwayBrowser/#/R-CFA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Canis familiaris 15377 R-CFA-77325 https://reactome.org/PathwayBrowser/#/R-CFA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Canis familiaris 15377 R-CFA-77333 https://reactome.org/PathwayBrowser/#/R-CFA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Canis familiaris 15377 R-CFA-77344 https://reactome.org/PathwayBrowser/#/R-CFA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Canis familiaris 15377 R-CFA-77614 https://reactome.org/PathwayBrowser/#/R-CFA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Canis familiaris 15377 R-CFA-77615 https://reactome.org/PathwayBrowser/#/R-CFA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Canis familiaris 15377 R-CFA-83677 https://reactome.org/PathwayBrowser/#/R-CFA-83677 C4 deamination of cytidine IEA Canis familiaris 15377 R-CFA-8847579 https://reactome.org/PathwayBrowser/#/R-CFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15377 R-CFA-8848053 https://reactome.org/PathwayBrowser/#/R-CFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Canis familiaris 15377 R-CFA-8848215 https://reactome.org/PathwayBrowser/#/R-CFA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Canis familiaris 15377 R-CFA-8848338 https://reactome.org/PathwayBrowser/#/R-CFA-8848338 PNPLA4 hydrolyzes TAG IEA Canis familiaris 15377 R-CFA-8848339 https://reactome.org/PathwayBrowser/#/R-CFA-8848339 PNPLA5 hydrolyzes TAG IEA Canis familiaris 15377 R-CFA-8848355 https://reactome.org/PathwayBrowser/#/R-CFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Canis familiaris 15377 R-CFA-8848484 https://reactome.org/PathwayBrowser/#/R-CFA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Canis familiaris 15377 R-CFA-8849969 https://reactome.org/PathwayBrowser/#/R-CFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Canis familiaris 15377 R-CFA-8850594 https://reactome.org/PathwayBrowser/#/R-CFA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Canis familiaris 15377 R-CFA-8850846 https://reactome.org/PathwayBrowser/#/R-CFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-CFA-8850854 https://reactome.org/PathwayBrowser/#/R-CFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-CFA-8851110 https://reactome.org/PathwayBrowser/#/R-CFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-CFA-8851129 https://reactome.org/PathwayBrowser/#/R-CFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-CFA-8852200 https://reactome.org/PathwayBrowser/#/R-CFA-8852200 Inactivation of LCK by PTPN22 IEA Canis familiaris 15377 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 15377 R-CFA-8853686 https://reactome.org/PathwayBrowser/#/R-CFA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Canis familiaris 15377 R-CFA-8854173 https://reactome.org/PathwayBrowser/#/R-CFA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Canis familiaris 15377 R-CFA-8854255 https://reactome.org/PathwayBrowser/#/R-CFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 15377 R-CFA-8854329 https://reactome.org/PathwayBrowser/#/R-CFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 15377 R-CFA-8854604 https://reactome.org/PathwayBrowser/#/R-CFA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Canis familiaris 15377 R-CFA-8854612 https://reactome.org/PathwayBrowser/#/R-CFA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Canis familiaris 15377 R-CFA-8855381 https://reactome.org/PathwayBrowser/#/R-CFA-8855381 PTPN22 dephosphorylates ZAP70 IEA Canis familiaris 15377 R-CFA-8855490 https://reactome.org/PathwayBrowser/#/R-CFA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Canis familiaris 15377 R-CFA-8855825 https://reactome.org/PathwayBrowser/#/R-CFA-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Canis familiaris 15377 R-CFA-8856951 https://reactome.org/PathwayBrowser/#/R-CFA-8856951 PP2A demethylation by PPME1 IEA Canis familiaris 15377 R-CFA-8862184 https://reactome.org/PathwayBrowser/#/R-CFA-8862184 USP48 cleaves polyubiquitin IEA Canis familiaris 15377 R-CFA-8862320 https://reactome.org/PathwayBrowser/#/R-CFA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Canis familiaris 15377 R-CFA-8863804 https://reactome.org/PathwayBrowser/#/R-CFA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Canis familiaris 15377 R-CFA-8864029 https://reactome.org/PathwayBrowser/#/R-CFA-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Canis familiaris 15377 R-CFA-8864036 https://reactome.org/PathwayBrowser/#/R-CFA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Canis familiaris 15377 R-CFA-8864125 https://reactome.org/PathwayBrowser/#/R-CFA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Canis familiaris 15377 R-CFA-8865667 https://reactome.org/PathwayBrowser/#/R-CFA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Canis familiaris 15377 R-CFA-8866405 https://reactome.org/PathwayBrowser/#/R-CFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 15377 R-CFA-8866542 https://reactome.org/PathwayBrowser/#/R-CFA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Canis familiaris 15377 R-CFA-8866601 https://reactome.org/PathwayBrowser/#/R-CFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Canis familiaris 15377 R-CFA-8867047 https://reactome.org/PathwayBrowser/#/R-CFA-8867047 PTPN3 dephosphorylates EPS15 IEA Canis familiaris 15377 R-CFA-8867344 https://reactome.org/PathwayBrowser/#/R-CFA-8867344 OMA1 hydrolyses OPA1 IEA Canis familiaris 15377 R-CFA-8867658 https://reactome.org/PathwayBrowser/#/R-CFA-8867658 PTPN3 dephosphorylates MAPK12 IEA Canis familiaris 15377 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 15377 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 15377 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 15377 R-CFA-8869206 https://reactome.org/PathwayBrowser/#/R-CFA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Canis familiaris 15377 R-CFA-8869425 https://reactome.org/PathwayBrowser/#/R-CFA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Canis familiaris 15377 R-CFA-8869456 https://reactome.org/PathwayBrowser/#/R-CFA-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Canis familiaris 15377 R-CFA-8869506 https://reactome.org/PathwayBrowser/#/R-CFA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Canis familiaris 15377 R-CFA-8870346 https://reactome.org/PathwayBrowser/#/R-CFA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Canis familiaris 15377 R-CFA-8874435 https://reactome.org/PathwayBrowser/#/R-CFA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Canis familiaris 15377 R-CFA-8875443 https://reactome.org/PathwayBrowser/#/R-CFA-8875443 USP8 deubiquitinates LRIG1 IEA Canis familiaris 15377 R-CFA-8878581 https://reactome.org/PathwayBrowser/#/R-CFA-8878581 TYRP1 oxidises DHICA to IQCA IEA Canis familiaris 15377 R-CFA-8878654 https://reactome.org/PathwayBrowser/#/R-CFA-8878654 ACP6 hydrolyses MYS-LPA IEA Canis familiaris 15377 R-CFA-8878787 https://reactome.org/PathwayBrowser/#/R-CFA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Canis familiaris 15377 R-CFA-888548 https://reactome.org/PathwayBrowser/#/R-CFA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Canis familiaris 15377 R-CFA-8932633 https://reactome.org/PathwayBrowser/#/R-CFA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Canis familiaris 15377 R-CFA-8933328 https://reactome.org/PathwayBrowser/#/R-CFA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Canis familiaris 15377 R-CFA-8933635 https://reactome.org/PathwayBrowser/#/R-CFA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Canis familiaris 15377 R-CFA-8936442 https://reactome.org/PathwayBrowser/#/R-CFA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Canis familiaris 15377 R-CFA-8937767 https://reactome.org/PathwayBrowser/#/R-CFA-8937767 PTPN11 dephosphorylates RUNX1 IEA Canis familiaris 15377 R-CFA-8938076 https://reactome.org/PathwayBrowser/#/R-CFA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Canis familiaris 15377 R-CFA-8940070 https://reactome.org/PathwayBrowser/#/R-CFA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Canis familiaris 15377 R-CFA-8940074 https://reactome.org/PathwayBrowser/#/R-CFA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Canis familiaris 15377 R-CFA-8940388 https://reactome.org/PathwayBrowser/#/R-CFA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Canis familiaris 15377 R-CFA-8943279 https://reactome.org/PathwayBrowser/#/R-CFA-8943279 GGT dimers hydrolyse GSH IEA Canis familiaris 15377 R-CFA-8952137 https://reactome.org/PathwayBrowser/#/R-CFA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Canis familiaris 15377 R-CFA-8952251 https://reactome.org/PathwayBrowser/#/R-CFA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Canis familiaris 15377 R-CFA-8953339 https://reactome.org/PathwayBrowser/#/R-CFA-8953339 DNPH1 hydrolyses dGMP IEA Canis familiaris 15377 R-CFA-8953499 https://reactome.org/PathwayBrowser/#/R-CFA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Canis familiaris 15377 R-CFA-8954398 https://reactome.org/PathwayBrowser/#/R-CFA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Canis familiaris 15377 R-CFA-8955817 https://reactome.org/PathwayBrowser/#/R-CFA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Canis familiaris 15377 R-CFA-8957389 https://reactome.org/PathwayBrowser/#/R-CFA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Canis familiaris 15377 R-CFA-8959510 https://reactome.org/PathwayBrowser/#/R-CFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Canis familiaris 15377 R-CFA-8979996 https://reactome.org/PathwayBrowser/#/R-CFA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Canis familiaris 15377 R-CFA-8980228 https://reactome.org/PathwayBrowser/#/R-CFA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Canis familiaris 15377 R-CFA-8981637 https://reactome.org/PathwayBrowser/#/R-CFA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Canis familiaris 15377 R-CFA-8985594 https://reactome.org/PathwayBrowser/#/R-CFA-8985594 MYO9B inactivates RHOA IEA Canis familiaris 15377 R-CFA-9008822 https://reactome.org/PathwayBrowser/#/R-CFA-9008822 PPM1D dephosphorylates RUNX2 IEA Canis familiaris 15377 R-CFA-9009950 https://reactome.org/PathwayBrowser/#/R-CFA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Canis familiaris 15377 R-CFA-9013022 https://reactome.org/PathwayBrowser/#/R-CFA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Canis familiaris 15377 R-CFA-9013111 https://reactome.org/PathwayBrowser/#/R-CFA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Canis familiaris 15377 R-CFA-9013144 https://reactome.org/PathwayBrowser/#/R-CFA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Canis familiaris 15377 R-CFA-9013161 https://reactome.org/PathwayBrowser/#/R-CFA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Canis familiaris 15377 R-CFA-9013437 https://reactome.org/PathwayBrowser/#/R-CFA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Canis familiaris 15377 R-CFA-9014295 https://reactome.org/PathwayBrowser/#/R-CFA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Canis familiaris 15377 R-CFA-9014434 https://reactome.org/PathwayBrowser/#/R-CFA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Canis familiaris 15377 R-CFA-9014627 https://reactome.org/PathwayBrowser/#/R-CFA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Canis familiaris 15377 R-CFA-9014741 https://reactome.org/PathwayBrowser/#/R-CFA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Canis familiaris 15377 R-CFA-9017488 https://reactome.org/PathwayBrowser/#/R-CFA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Canis familiaris 15377 R-CFA-9018745 https://reactome.org/PathwayBrowser/#/R-CFA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Canis familiaris 15377 R-CFA-9018806 https://reactome.org/PathwayBrowser/#/R-CFA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Canis familiaris 15377 R-CFA-9018814 https://reactome.org/PathwayBrowser/#/R-CFA-9018814 RHOT1 hydrolyzes GTP IEA Canis familiaris 15377 R-CFA-9018862 https://reactome.org/PathwayBrowser/#/R-CFA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Canis familiaris 15377 R-CFA-9018868 https://reactome.org/PathwayBrowser/#/R-CFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Canis familiaris 15377 R-CFA-9018877 https://reactome.org/PathwayBrowser/#/R-CFA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Canis familiaris 15377 R-CFA-9018895 https://reactome.org/PathwayBrowser/#/R-CFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Canis familiaris 15377 R-CFA-9020252 https://reactome.org/PathwayBrowser/#/R-CFA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Canis familiaris 15377 R-CFA-9020253 https://reactome.org/PathwayBrowser/#/R-CFA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Canis familiaris 15377 R-CFA-9020257 https://reactome.org/PathwayBrowser/#/R-CFA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Canis familiaris 15377 R-CFA-9020258 https://reactome.org/PathwayBrowser/#/R-CFA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Canis familiaris 15377 R-CFA-9020270 https://reactome.org/PathwayBrowser/#/R-CFA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Canis familiaris 15377 R-CFA-9020271 https://reactome.org/PathwayBrowser/#/R-CFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Canis familiaris 15377 R-CFA-9020273 https://reactome.org/PathwayBrowser/#/R-CFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Canis familiaris 15377 R-CFA-9024890 https://reactome.org/PathwayBrowser/#/R-CFA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Canis familiaris 15377 R-CFA-9027043 https://reactome.org/PathwayBrowser/#/R-CFA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Canis familiaris 15377 R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 15377 R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 15377 R-CFA-9033520 https://reactome.org/PathwayBrowser/#/R-CFA-9033520 TYSND1 cleaves TYSND1 IEA Canis familiaris 15377 R-CFA-9034539 https://reactome.org/PathwayBrowser/#/R-CFA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Canis familiaris 15377 R-CFA-9036727 https://reactome.org/PathwayBrowser/#/R-CFA-9036727 GAA hydrolyzes lysosomal glycogen IEA Canis familiaris 15377 R-CFA-917841 https://reactome.org/PathwayBrowser/#/R-CFA-917841 Acidification of Tf:TfR1 containing endosome IEA Canis familiaris 15377 R-CFA-917891 https://reactome.org/PathwayBrowser/#/R-CFA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Canis familiaris 15377 R-CFA-917933 https://reactome.org/PathwayBrowser/#/R-CFA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Canis familiaris 15377 R-CFA-917979 https://reactome.org/PathwayBrowser/#/R-CFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Canis familiaris 15377 R-CFA-936802 https://reactome.org/PathwayBrowser/#/R-CFA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Canis familiaris 15377 R-CFA-936883 https://reactome.org/PathwayBrowser/#/R-CFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Canis familiaris 15377 R-CFA-936895 https://reactome.org/PathwayBrowser/#/R-CFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Canis familiaris 15377 R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 15377 R-CFA-937311 https://reactome.org/PathwayBrowser/#/R-CFA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Canis familiaris 15377 R-CFA-939763 https://reactome.org/PathwayBrowser/#/R-CFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Canis familiaris 15377 R-CFA-947531 https://reactome.org/PathwayBrowser/#/R-CFA-947531 Molybdenum ion transfer onto molybdopterin IEA Canis familiaris 15377 R-CFA-947535 https://reactome.org/PathwayBrowser/#/R-CFA-947535 Cyclisation of GTP to precursor Z IEA Canis familiaris 15377 R-CFA-947591 https://reactome.org/PathwayBrowser/#/R-CFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Canis familiaris 15377 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 15377 R-CFA-9620103 https://reactome.org/PathwayBrowser/#/R-CFA-9620103 ALDH2 transforms GTN to NO IEA Canis familiaris 15377 R-CFA-9624893 https://reactome.org/PathwayBrowser/#/R-CFA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Canis familiaris 15377 R-CFA-9629675 https://reactome.org/PathwayBrowser/#/R-CFA-9629675 PDE3A hydrolyses cAMP to AMP IEA Canis familiaris 15377 R-CFA-9638075 https://reactome.org/PathwayBrowser/#/R-CFA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Canis familiaris 15377 R-CFA-9638076 https://reactome.org/PathwayBrowser/#/R-CFA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Canis familiaris 15377 R-CFA-9638078 https://reactome.org/PathwayBrowser/#/R-CFA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Canis familiaris 15377 R-CFA-9638120 https://reactome.org/PathwayBrowser/#/R-CFA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 15377 R-CFA-9644869 https://reactome.org/PathwayBrowser/#/R-CFA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Canis familiaris 15377 R-CFA-9647994 https://reactome.org/PathwayBrowser/#/R-CFA-9647994 RAS proteins are depalmitoylated IEA Canis familiaris 15377 R-CFA-965067 https://reactome.org/PathwayBrowser/#/R-CFA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Canis familiaris 15377 R-CFA-965079 https://reactome.org/PathwayBrowser/#/R-CFA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Canis familiaris 15377 R-CFA-9653514 https://reactome.org/PathwayBrowser/#/R-CFA-9653514 USP17L2 deubiquitinates RCE1 IEA Canis familiaris 15377 R-CFA-9656891 https://reactome.org/PathwayBrowser/#/R-CFA-9656891 OPN1SW binds 11cRAL IEA Canis familiaris 15377 R-CFA-9656893 https://reactome.org/PathwayBrowser/#/R-CFA-9656893 OPN1MW binds 11cRAL IEA Canis familiaris 15377 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 15377 R-CFA-9661417 https://reactome.org/PathwayBrowser/#/R-CFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 15377 R-CFA-9667952 https://reactome.org/PathwayBrowser/#/R-CFA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Canis familiaris 15377 R-CFA-9668419 https://reactome.org/PathwayBrowser/#/R-CFA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Canis familiaris 15377 R-CFA-9673053 https://reactome.org/PathwayBrowser/#/R-CFA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Canis familiaris 15377 R-CFA-9673054 https://reactome.org/PathwayBrowser/#/R-CFA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Canis familiaris 15377 R-CFA-9674127 https://reactome.org/PathwayBrowser/#/R-CFA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Canis familiaris 15377 R-CFA-9686524 https://reactome.org/PathwayBrowser/#/R-CFA-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Canis familiaris 15377 R-CFA-9693282 https://reactome.org/PathwayBrowser/#/R-CFA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Canis familiaris 15377 R-CFA-9698408 https://reactome.org/PathwayBrowser/#/R-CFA-9698408 PTPRJ dephosphorylates active FLT3 IEA Canis familiaris 15377 R-CFA-9700200 https://reactome.org/PathwayBrowser/#/R-CFA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Canis familiaris 15377 R-CFA-9701507 https://reactome.org/PathwayBrowser/#/R-CFA-9701507 PTPN6 dephosphorylates JAK3 IEA Canis familiaris 15377 R-CFA-9701565 https://reactome.org/PathwayBrowser/#/R-CFA-9701565 HDACs deacetylate p-STAT3 dimers IEA Canis familiaris 15377 R-CFA-9705507 https://reactome.org/PathwayBrowser/#/R-CFA-9705507 PDE3B hydrolyses cAMP to AMP IEA Canis familiaris 15377 R-CFA-9706399 https://reactome.org/PathwayBrowser/#/R-CFA-9706399 RHOBTB3 hydrolyzes ATP IEA Canis familiaris 15377 R-CFA-9708261 https://reactome.org/PathwayBrowser/#/R-CFA-9708261 PDE4A hydrolyses cAMP to AMP IEA Canis familiaris 15377 R-CFA-9709360 https://reactome.org/PathwayBrowser/#/R-CFA-9709360 H2O2 reduces MetHb IEA Canis familiaris 15377 R-CFA-9727198 https://reactome.org/PathwayBrowser/#/R-CFA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Canis familiaris 15377 R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 15377 R-CFA-9727349 https://reactome.org/PathwayBrowser/#/R-CFA-9727349 XDH dehydrogenates xanthine to form urate IEA Canis familiaris 15377 R-CFA-9727567 https://reactome.org/PathwayBrowser/#/R-CFA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Canis familiaris 15377 R-CFA-9731228 https://reactome.org/PathwayBrowser/#/R-CFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Canis familiaris 15377 R-CFA-9731590 https://reactome.org/PathwayBrowser/#/R-CFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Canis familiaris 15377 R-CFA-9731613 https://reactome.org/PathwayBrowser/#/R-CFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Canis familiaris 15377 R-CFA-9731632 https://reactome.org/PathwayBrowser/#/R-CFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Canis familiaris 15377 R-CFA-9731661 https://reactome.org/PathwayBrowser/#/R-CFA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Canis familiaris 15377 R-CFA-9748945 https://reactome.org/PathwayBrowser/#/R-CFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Canis familiaris 15377 R-CFA-9748957 https://reactome.org/PathwayBrowser/#/R-CFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Canis familiaris 15377 R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 15377 R-CFA-9749609 https://reactome.org/PathwayBrowser/#/R-CFA-9749609 BCHE hydrolyzes ASA- IEA Canis familiaris 15377 R-CFA-9749647 https://reactome.org/PathwayBrowser/#/R-CFA-9749647 CES2 hydrolyzes ASA- IEA Canis familiaris 15377 R-CFA-9749792 https://reactome.org/PathwayBrowser/#/R-CFA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Canis familiaris 15377 R-CFA-9749986 https://reactome.org/PathwayBrowser/#/R-CFA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Canis familiaris 15377 R-CFA-9750016 https://reactome.org/PathwayBrowser/#/R-CFA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Canis familiaris 15377 R-CFA-9750546 https://reactome.org/PathwayBrowser/#/R-CFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 15377 R-CFA-9750555 https://reactome.org/PathwayBrowser/#/R-CFA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Canis familiaris 15377 R-CFA-9750617 https://reactome.org/PathwayBrowser/#/R-CFA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 15377 R-CFA-9750656 https://reactome.org/PathwayBrowser/#/R-CFA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Canis familiaris 15377 R-CFA-9750942 https://reactome.org/PathwayBrowser/#/R-CFA-9750942 USP14 deubiquitinates NLRC5 IEA Canis familiaris 15377 R-CFA-9753278 https://reactome.org/PathwayBrowser/#/R-CFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 15377 R-CFA-9753280 https://reactome.org/PathwayBrowser/#/R-CFA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Canis familiaris 15377 R-CFA-9753283 https://reactome.org/PathwayBrowser/#/R-CFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 15377 R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 15377 R-CFA-9753285 https://reactome.org/PathwayBrowser/#/R-CFA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Canis familiaris 15377 R-CFA-9753632 https://reactome.org/PathwayBrowser/#/R-CFA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Canis familiaris 15377 R-CFA-9753634 https://reactome.org/PathwayBrowser/#/R-CFA-9753634 GGT dimers hydrolyse APAP-SG IEA Canis familiaris 15377 R-CFA-9753944 https://reactome.org/PathwayBrowser/#/R-CFA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Canis familiaris 15377 R-CFA-9754964 https://reactome.org/PathwayBrowser/#/R-CFA-9754964 ADA deamidates RBV IEA Canis familiaris 15377 R-CFA-9755030 https://reactome.org/PathwayBrowser/#/R-CFA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Canis familiaris 15377 R-CFA-9755078 https://reactome.org/PathwayBrowser/#/R-CFA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Canis familiaris 15377 R-CFA-975594 https://reactome.org/PathwayBrowser/#/R-CFA-975594 PLB1 hydrolyses RPALM to atROL IEA Canis familiaris 15377 R-CFA-9756138 https://reactome.org/PathwayBrowser/#/R-CFA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Canis familiaris 15377 R-CFA-9756162 https://reactome.org/PathwayBrowser/#/R-CFA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Canis familiaris 15377 R-CFA-9756169 https://reactome.org/PathwayBrowser/#/R-CFA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Canis familiaris 15377 R-CFA-9756177 https://reactome.org/PathwayBrowser/#/R-CFA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Canis familiaris 15377 R-CFA-9756180 https://reactome.org/PathwayBrowser/#/R-CFA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Canis familiaris 15377 R-CFA-9758674 https://reactome.org/PathwayBrowser/#/R-CFA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Canis familiaris 15377 R-CFA-9759206 https://reactome.org/PathwayBrowser/#/R-CFA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Canis familiaris 15377 R-CFA-9759454 https://reactome.org/PathwayBrowser/#/R-CFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Canis familiaris 15377 R-CFA-9759461 https://reactome.org/PathwayBrowser/#/R-CFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Canis familiaris 15377 R-CFA-977324 https://reactome.org/PathwayBrowser/#/R-CFA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Canis familiaris 15377 R-CFA-9794120 https://reactome.org/PathwayBrowser/#/R-CFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Canis familiaris 15377 R-CFA-9794572 https://reactome.org/PathwayBrowser/#/R-CFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Canis familiaris 15377 R-CFA-983422 https://reactome.org/PathwayBrowser/#/R-CFA-983422 Disassembly of COPII coated vesicle IEA Canis familiaris 15377 R-CFA-9837419 https://reactome.org/PathwayBrowser/#/R-CFA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Canis familiaris 15377 R-CFA-9838004 https://reactome.org/PathwayBrowser/#/R-CFA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Canis familiaris 15377 R-CFA-9838081 https://reactome.org/PathwayBrowser/#/R-CFA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Canis familiaris 15377 R-CFA-9838289 https://reactome.org/PathwayBrowser/#/R-CFA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Canis familiaris 15377 R-CFA-9839059 https://reactome.org/PathwayBrowser/#/R-CFA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Canis familiaris 15377 R-CFA-9839072 https://reactome.org/PathwayBrowser/#/R-CFA-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Canis familiaris 15377 R-CFA-9839105 https://reactome.org/PathwayBrowser/#/R-CFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Canis familiaris 15377 R-CFA-9839110 https://reactome.org/PathwayBrowser/#/R-CFA-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Canis familiaris 15377 R-CFA-9839113 https://reactome.org/PathwayBrowser/#/R-CFA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Canis familiaris 15377 R-CFA-9840408 https://reactome.org/PathwayBrowser/#/R-CFA-9840408 OMA1 cleaves DELE1 IEA Canis familiaris 15377 R-CFA-9840795 https://reactome.org/PathwayBrowser/#/R-CFA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Canis familiaris 15377 R-CFA-9840833 https://reactome.org/PathwayBrowser/#/R-CFA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Canis familiaris 15377 R-CFA-9840884 https://reactome.org/PathwayBrowser/#/R-CFA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Canis familiaris 15377 R-CFA-9840949 https://reactome.org/PathwayBrowser/#/R-CFA-9840949 ARSA removes sulfate from SM3 IEA Canis familiaris 15377 R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 15377 R-CFA-9843721 https://reactome.org/PathwayBrowser/#/R-CFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Canis familiaris 15377 R-CFA-9853385 https://reactome.org/PathwayBrowser/#/R-CFA-9853385 PPP1CC dephosphorylates PLK1 IEA Canis familiaris 15377 R-CFA-9861626 https://reactome.org/PathwayBrowser/#/R-CFA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Canis familiaris 15377 R-CFA-9861725 https://reactome.org/PathwayBrowser/#/R-CFA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Canis familiaris 15377 R-CFA-997309 https://reactome.org/PathwayBrowser/#/R-CFA-997309 Dephosphorylation of STAT1 by SHP2 IEA Canis familiaris 15377 R-CFA-997311 https://reactome.org/PathwayBrowser/#/R-CFA-997311 Dephosphorylation of TYK2 by PTP1B IEA Canis familiaris 15377 R-CFA-997314 https://reactome.org/PathwayBrowser/#/R-CFA-997314 Dephosphorylation of JAK1 by SHP1 IEA Canis familiaris 15377 R-CFA-997326 https://reactome.org/PathwayBrowser/#/R-CFA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Canis familiaris 15377 R-DDI-111751 https://reactome.org/PathwayBrowser/#/R-DDI-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 15377 R-DDI-111804 https://reactome.org/PathwayBrowser/#/R-DDI-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 15377 R-DDI-111879 https://reactome.org/PathwayBrowser/#/R-DDI-111879 PIP2 hydrolysis IEA Dictyostelium discoideum 15377 R-DDI-111955 https://reactome.org/PathwayBrowser/#/R-DDI-111955 cAMP hydrolysis by Cam-PDE 1 IEA Dictyostelium discoideum 15377 R-DDI-111962 https://reactome.org/PathwayBrowser/#/R-DDI-111962 PDE4A,C,D hydrolyse cAMP IEA Dictyostelium discoideum 15377 R-DDI-112037 https://reactome.org/PathwayBrowser/#/R-DDI-112037 Inactivation of PLC beta IEA Dictyostelium discoideum 15377 R-DDI-113503 https://reactome.org/PathwayBrowser/#/R-DDI-113503 PP2A mediated localization of RB1 protein in chromatin IEA Dictyostelium discoideum 15377 R-DDI-1237129 https://reactome.org/PathwayBrowser/#/R-DDI-1237129 Acireductone is created IEA Dictyostelium discoideum 15377 R-DDI-1247910 https://reactome.org/PathwayBrowser/#/R-DDI-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Dictyostelium discoideum 15377 R-DDI-1247935 https://reactome.org/PathwayBrowser/#/R-DDI-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Dictyostelium discoideum 15377 R-DDI-1363274 https://reactome.org/PathwayBrowser/#/R-DDI-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Dictyostelium discoideum 15377 R-DDI-1363276 https://reactome.org/PathwayBrowser/#/R-DDI-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Dictyostelium discoideum 15377 R-DDI-1369028 https://reactome.org/PathwayBrowser/#/R-DDI-1369028 ABCAs mediate lipid efflux IEA Dictyostelium discoideum 15377 R-DDI-1369052 https://reactome.org/PathwayBrowser/#/R-DDI-1369052 ABCAs mediate lipid influx IEA Dictyostelium discoideum 15377 R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 15377 R-DDI-141186 https://reactome.org/PathwayBrowser/#/R-DDI-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Dictyostelium discoideum 15377 R-DDI-141200 https://reactome.org/PathwayBrowser/#/R-DDI-141200 MAOB:FAD oxidatively deaminates of PEA IEA Dictyostelium discoideum 15377 R-DDI-141202 https://reactome.org/PathwayBrowser/#/R-DDI-141202 MAOB:FAD oxidatively deaminates TYR IEA Dictyostelium discoideum 15377 R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 15377 R-DDI-1454916 https://reactome.org/PathwayBrowser/#/R-DDI-1454916 The ABCC family mediates organic anion transport IEA Dictyostelium discoideum 15377 R-DDI-1454928 https://reactome.org/PathwayBrowser/#/R-DDI-1454928 ABCG4 may mediate cholesterol efflux IEA Dictyostelium discoideum 15377 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-1467466 https://reactome.org/PathwayBrowser/#/R-DDI-1467466 ABCA4 mediates atRAL transport IEA Dictyostelium discoideum 15377 R-DDI-1474146 https://reactome.org/PathwayBrowser/#/R-DDI-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Dictyostelium discoideum 15377 R-DDI-1482543 https://reactome.org/PathwayBrowser/#/R-DDI-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Dictyostelium discoideum 15377 R-DDI-1482612 https://reactome.org/PathwayBrowser/#/R-DDI-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Dictyostelium discoideum 15377 R-DDI-1482685 https://reactome.org/PathwayBrowser/#/R-DDI-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Dictyostelium discoideum 15377 R-DDI-1482816 https://reactome.org/PathwayBrowser/#/R-DDI-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Dictyostelium discoideum 15377 R-DDI-1482825 https://reactome.org/PathwayBrowser/#/R-DDI-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Dictyostelium discoideum 15377 R-DDI-1482856 https://reactome.org/PathwayBrowser/#/R-DDI-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Dictyostelium discoideum 15377 R-DDI-1482884 https://reactome.org/PathwayBrowser/#/R-DDI-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Dictyostelium discoideum 15377 R-DDI-1482887 https://reactome.org/PathwayBrowser/#/R-DDI-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Dictyostelium discoideum 15377 R-DDI-1483182 https://reactome.org/PathwayBrowser/#/R-DDI-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Dictyostelium discoideum 15377 R-DDI-1483203 https://reactome.org/PathwayBrowser/#/R-DDI-1483203 PA is dephosphorylated to DAG by LPIN IEA Dictyostelium discoideum 15377 R-DDI-156526 https://reactome.org/PathwayBrowser/#/R-DDI-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Dictyostelium discoideum 15377 R-DDI-1605624 https://reactome.org/PathwayBrowser/#/R-DDI-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Dictyostelium discoideum 15377 R-DDI-1605632 https://reactome.org/PathwayBrowser/#/R-DDI-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Dictyostelium discoideum 15377 R-DDI-1605736 https://reactome.org/PathwayBrowser/#/R-DDI-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Dictyostelium discoideum 15377 R-DDI-1605797 https://reactome.org/PathwayBrowser/#/R-DDI-1605797 SMPD1 hydrolyzes SPHM IEA Dictyostelium discoideum 15377 R-DDI-1606273 https://reactome.org/PathwayBrowser/#/R-DDI-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Dictyostelium discoideum 15377 R-DDI-1606312 https://reactome.org/PathwayBrowser/#/R-DDI-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Dictyostelium discoideum 15377 R-DDI-1606583 https://reactome.org/PathwayBrowser/#/R-DDI-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Dictyostelium discoideum 15377 R-DDI-1614524 https://reactome.org/PathwayBrowser/#/R-DDI-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Dictyostelium discoideum 15377 R-DDI-1614544 https://reactome.org/PathwayBrowser/#/R-DDI-1614544 Sulfite is oxidized to sulfate IEA Dictyostelium discoideum 15377 R-DDI-1614583 https://reactome.org/PathwayBrowser/#/R-DDI-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Dictyostelium discoideum 15377 R-DDI-1614614 https://reactome.org/PathwayBrowser/#/R-DDI-1614614 Cysteine is degraded to serine and H2S IEA Dictyostelium discoideum 15377 R-DDI-1614631 https://reactome.org/PathwayBrowser/#/R-DDI-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Dictyostelium discoideum 15377 R-DDI-162425 https://reactome.org/PathwayBrowser/#/R-DDI-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Dictyostelium discoideum 15377 R-DDI-162857 https://reactome.org/PathwayBrowser/#/R-DDI-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Dictyostelium discoideum 15377 R-DDI-1630306 https://reactome.org/PathwayBrowser/#/R-DDI-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Dictyostelium discoideum 15377 R-DDI-1638053 https://reactome.org/PathwayBrowser/#/R-DDI-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Dictyostelium discoideum 15377 R-DDI-1640164 https://reactome.org/PathwayBrowser/#/R-DDI-1640164 ENPP7 hydrolyzes sphingomyelin IEA Dictyostelium discoideum 15377 R-DDI-1655453 https://reactome.org/PathwayBrowser/#/R-DDI-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Dictyostelium discoideum 15377 R-DDI-1675795 https://reactome.org/PathwayBrowser/#/R-DDI-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Dictyostelium discoideum 15377 R-DDI-1675824 https://reactome.org/PathwayBrowser/#/R-DDI-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Dictyostelium discoideum 15377 R-DDI-1675836 https://reactome.org/PathwayBrowser/#/R-DDI-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-1675949 https://reactome.org/PathwayBrowser/#/R-DDI-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-1675988 https://reactome.org/PathwayBrowser/#/R-DDI-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-1675994 https://reactome.org/PathwayBrowser/#/R-DDI-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-1676065 https://reactome.org/PathwayBrowser/#/R-DDI-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Dictyostelium discoideum 15377 R-DDI-1676105 https://reactome.org/PathwayBrowser/#/R-DDI-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Dictyostelium discoideum 15377 R-DDI-1676114 https://reactome.org/PathwayBrowser/#/R-DDI-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Dictyostelium discoideum 15377 R-DDI-1676124 https://reactome.org/PathwayBrowser/#/R-DDI-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Dictyostelium discoideum 15377 R-DDI-1676141 https://reactome.org/PathwayBrowser/#/R-DDI-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Dictyostelium discoideum 15377 R-DDI-1676149 https://reactome.org/PathwayBrowser/#/R-DDI-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-1676177 https://reactome.org/PathwayBrowser/#/R-DDI-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-1676203 https://reactome.org/PathwayBrowser/#/R-DDI-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-1676204 https://reactome.org/PathwayBrowser/#/R-DDI-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Dictyostelium discoideum 15377 R-DDI-1678716 https://reactome.org/PathwayBrowser/#/R-DDI-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Dictyostelium discoideum 15377 R-DDI-1678742 https://reactome.org/PathwayBrowser/#/R-DDI-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Dictyostelium discoideum 15377 R-DDI-174391 https://reactome.org/PathwayBrowser/#/R-DDI-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Dictyostelium discoideum 15377 R-DDI-174401 https://reactome.org/PathwayBrowser/#/R-DDI-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Dictyostelium discoideum 15377 R-DDI-176606 https://reactome.org/PathwayBrowser/#/R-DDI-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Dictyostelium discoideum 15377 R-DDI-1793186 https://reactome.org/PathwayBrowser/#/R-DDI-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Dictyostelium discoideum 15377 R-DDI-1855154 https://reactome.org/PathwayBrowser/#/R-DDI-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855159 https://reactome.org/PathwayBrowser/#/R-DDI-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855163 https://reactome.org/PathwayBrowser/#/R-DDI-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 15377 R-DDI-1855165 https://reactome.org/PathwayBrowser/#/R-DDI-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855166 https://reactome.org/PathwayBrowser/#/R-DDI-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855171 https://reactome.org/PathwayBrowser/#/R-DDI-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855174 https://reactome.org/PathwayBrowser/#/R-DDI-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855177 https://reactome.org/PathwayBrowser/#/R-DDI-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-1855198 https://reactome.org/PathwayBrowser/#/R-DDI-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855200 https://reactome.org/PathwayBrowser/#/R-DDI-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 15377 R-DDI-1855205 https://reactome.org/PathwayBrowser/#/R-DDI-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855208 https://reactome.org/PathwayBrowser/#/R-DDI-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855210 https://reactome.org/PathwayBrowser/#/R-DDI-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855211 https://reactome.org/PathwayBrowser/#/R-DDI-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855213 https://reactome.org/PathwayBrowser/#/R-DDI-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-1855214 https://reactome.org/PathwayBrowser/#/R-DDI-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Dictyostelium discoideum 15377 R-DDI-1855218 https://reactome.org/PathwayBrowser/#/R-DDI-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855219 https://reactome.org/PathwayBrowser/#/R-DDI-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1855221 https://reactome.org/PathwayBrowser/#/R-DDI-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-1855222 https://reactome.org/PathwayBrowser/#/R-DDI-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-1855225 https://reactome.org/PathwayBrowser/#/R-DDI-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 15377 R-DDI-1855232 https://reactome.org/PathwayBrowser/#/R-DDI-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-1861788 https://reactome.org/PathwayBrowser/#/R-DDI-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Dictyostelium discoideum 15377 R-DDI-189053 https://reactome.org/PathwayBrowser/#/R-DDI-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Dictyostelium discoideum 15377 R-DDI-189069 https://reactome.org/PathwayBrowser/#/R-DDI-189069 sucrose + H2O => glucose + fructose IEA Dictyostelium discoideum 15377 R-DDI-189102 https://reactome.org/PathwayBrowser/#/R-DDI-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Dictyostelium discoideum 15377 R-DDI-189421 https://reactome.org/PathwayBrowser/#/R-DDI-189421 CPO transforms COPRO3 to PPGEN9 IEA Dictyostelium discoideum 15377 R-DDI-189439 https://reactome.org/PathwayBrowser/#/R-DDI-189439 ALAD condenses 2 dALAs to form PBG IEA Dictyostelium discoideum 15377 R-DDI-189488 https://reactome.org/PathwayBrowser/#/R-DDI-189488 UROS transforms HMB to URO3 IEA Dictyostelium discoideum 15377 R-DDI-191101 https://reactome.org/PathwayBrowser/#/R-DDI-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 15377 R-DDI-191108 https://reactome.org/PathwayBrowser/#/R-DDI-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 15377 R-DDI-191116 https://reactome.org/PathwayBrowser/#/R-DDI-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Dictyostelium discoideum 15377 R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 15377 R-DDI-191323 https://reactome.org/PathwayBrowser/#/R-DDI-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Dictyostelium discoideum 15377 R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 15377 R-DDI-192331 https://reactome.org/PathwayBrowser/#/R-DDI-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-193362 https://reactome.org/PathwayBrowser/#/R-DDI-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-193535 https://reactome.org/PathwayBrowser/#/R-DDI-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-193964 https://reactome.org/PathwayBrowser/#/R-DDI-193964 CYP21A2 21-hydroxylates PROG IEA Dictyostelium discoideum 15377 R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 15377 R-DDI-194641 https://reactome.org/PathwayBrowser/#/R-DDI-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15377 R-DDI-194669 https://reactome.org/PathwayBrowser/#/R-DDI-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15377 R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 15377 R-DDI-196955 https://reactome.org/PathwayBrowser/#/R-DDI-196955 2xENPP1 hydrolyzes FAD to FMN IEA Dictyostelium discoideum 15377 R-DDI-197271 https://reactome.org/PathwayBrowser/#/R-DDI-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Dictyostelium discoideum 15377 R-DDI-199456 https://reactome.org/PathwayBrowser/#/R-DDI-199456 PTEN dephosphorylates PIP3 IEA Dictyostelium discoideum 15377 R-DDI-199959 https://reactome.org/PathwayBrowser/#/R-DDI-199959 ERKs are inactivated by protein phosphatase 2A IEA Dictyostelium discoideum 15377 R-DDI-200661 https://reactome.org/PathwayBrowser/#/R-DDI-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Dictyostelium discoideum 15377 R-DDI-200740 https://reactome.org/PathwayBrowser/#/R-DDI-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Dictyostelium discoideum 15377 R-DDI-201035 https://reactome.org/PathwayBrowser/#/R-DDI-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Dictyostelium discoideum 15377 R-DDI-2023971 https://reactome.org/PathwayBrowser/#/R-DDI-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-2023973 https://reactome.org/PathwayBrowser/#/R-DDI-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-202407 https://reactome.org/PathwayBrowser/#/R-DDI-202407 PLC-gamma1 hydrolyses PIP2 IEA Dictyostelium discoideum 15377 R-DDI-2029468 https://reactome.org/PathwayBrowser/#/R-DDI-2029468 Conversion of PA into DAG by PAP-1 IEA Dictyostelium discoideum 15377 R-DDI-2029471 https://reactome.org/PathwayBrowser/#/R-DDI-2029471 Hydrolysis of PC to PA by PLD IEA Dictyostelium discoideum 15377 R-DDI-203797 https://reactome.org/PathwayBrowser/#/R-DDI-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Dictyostelium discoideum 15377 R-DDI-2046083 https://reactome.org/PathwayBrowser/#/R-DDI-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-2046088 https://reactome.org/PathwayBrowser/#/R-DDI-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-2046090 https://reactome.org/PathwayBrowser/#/R-DDI-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-2046094 https://reactome.org/PathwayBrowser/#/R-DDI-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-2046095 https://reactome.org/PathwayBrowser/#/R-DDI-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-2046100 https://reactome.org/PathwayBrowser/#/R-DDI-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-204662 https://reactome.org/PathwayBrowser/#/R-DDI-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Dictyostelium discoideum 15377 R-DDI-2066778 https://reactome.org/PathwayBrowser/#/R-DDI-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-2090037 https://reactome.org/PathwayBrowser/#/R-DDI-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Dictyostelium discoideum 15377 R-DDI-2090038 https://reactome.org/PathwayBrowser/#/R-DDI-2090038 NAGLU hydrolyses heparan chain(2) IEA Dictyostelium discoideum 15377 R-DDI-2090079 https://reactome.org/PathwayBrowser/#/R-DDI-2090079 GLB1 hydrolyses linker chain(2) IEA Dictyostelium discoideum 15377 R-DDI-209845 https://reactome.org/PathwayBrowser/#/R-DDI-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Dictyostelium discoideum 15377 R-DDI-209973 https://reactome.org/PathwayBrowser/#/R-DDI-209973 Tyrosine is diiodinated IEA Dictyostelium discoideum 15377 R-DDI-2105001 https://reactome.org/PathwayBrowser/#/R-DDI-2105001 HEXA cleaves the terminal GalNAc from DS IEA Dictyostelium discoideum 15377 R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 15377 R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 15377 R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 15377 R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 15377 R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 15377 R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 15377 R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 15377 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 15377 R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 15377 R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 15377 R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 15377 R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 15377 R-DDI-2160492 https://reactome.org/PathwayBrowser/#/R-DDI-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Dictyostelium discoideum 15377 R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 15377 R-DDI-2161890 https://reactome.org/PathwayBrowser/#/R-DDI-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Dictyostelium discoideum 15377 R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Dictyostelium discoideum 15377 R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 15377 R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Dictyostelium discoideum 15377 R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 15377 R-DDI-2162225 https://reactome.org/PathwayBrowser/#/R-DDI-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Dictyostelium discoideum 15377 R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 15377 R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 15377 R-DDI-2393939 https://reactome.org/PathwayBrowser/#/R-DDI-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Dictyostelium discoideum 15377 R-DDI-2408551 https://reactome.org/PathwayBrowser/#/R-DDI-2408551 SeMet is converted to AdoSeMet by MAT IEA Dictyostelium discoideum 15377 R-DDI-2509827 https://reactome.org/PathwayBrowser/#/R-DDI-2509827 ITPA hydrolyses ITP to IMP IEA Dictyostelium discoideum 15377 R-DDI-2509831 https://reactome.org/PathwayBrowser/#/R-DDI-2509831 ITPA hydrolyses XTP to XMP IEA Dictyostelium discoideum 15377 R-DDI-2509838 https://reactome.org/PathwayBrowser/#/R-DDI-2509838 ITPA hydrolyses dITP to dIMP IEA Dictyostelium discoideum 15377 R-DDI-2529015 https://reactome.org/PathwayBrowser/#/R-DDI-2529015 Dephosphorylation of CK2-modified condensin I IEA Dictyostelium discoideum 15377 R-DDI-265783 https://reactome.org/PathwayBrowser/#/R-DDI-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-266051 https://reactome.org/PathwayBrowser/#/R-DDI-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Dictyostelium discoideum 15377 R-DDI-266072 https://reactome.org/PathwayBrowser/#/R-DDI-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Dictyostelium discoideum 15377 R-DDI-266082 https://reactome.org/PathwayBrowser/#/R-DDI-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Dictyostelium discoideum 15377 R-DDI-2995330 https://reactome.org/PathwayBrowser/#/R-DDI-2995330 COX10 transforms heme to heme O IEA Dictyostelium discoideum 15377 R-DDI-2995334 https://reactome.org/PathwayBrowser/#/R-DDI-2995334 COX15 transforms heme O to heme A IEA Dictyostelium discoideum 15377 R-DDI-3095901 https://reactome.org/PathwayBrowser/#/R-DDI-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-3204311 https://reactome.org/PathwayBrowser/#/R-DDI-3204311 AOX1 oxidises PXL to PDXate IEA Dictyostelium discoideum 15377 R-DDI-3322995 https://reactome.org/PathwayBrowser/#/R-DDI-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Dictyostelium discoideum 15377 R-DDI-3341343 https://reactome.org/PathwayBrowser/#/R-DDI-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Dictyostelium discoideum 15377 R-DDI-3343700 https://reactome.org/PathwayBrowser/#/R-DDI-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Dictyostelium discoideum 15377 R-DDI-350901 https://reactome.org/PathwayBrowser/#/R-DDI-350901 Iodide is organified IEA Dictyostelium discoideum 15377 R-DDI-3697882 https://reactome.org/PathwayBrowser/#/R-DDI-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Dictyostelium discoideum 15377 R-DDI-3697894 https://reactome.org/PathwayBrowser/#/R-DDI-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Dictyostelium discoideum 15377 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 15377 R-DDI-374909 https://reactome.org/PathwayBrowser/#/R-DDI-374909 Catabolism of Noradrenaline IEA Dictyostelium discoideum 15377 R-DDI-3769447 https://reactome.org/PathwayBrowser/#/R-DDI-3769447 HDAC1:2-containing complex deacetylate histones IEA Dictyostelium discoideum 15377 R-DDI-3782637 https://reactome.org/PathwayBrowser/#/R-DDI-3782637 HDAC8 deacetylates histones IEA Dictyostelium discoideum 15377 R-DDI-3782655 https://reactome.org/PathwayBrowser/#/R-DDI-3782655 HDAC10 deacetylates histone IEA Dictyostelium discoideum 15377 R-DDI-379382 https://reactome.org/PathwayBrowser/#/R-DDI-379382 MAOA:FAD deaminates DA to DOPAC IEA Dictyostelium discoideum 15377 R-DDI-379395 https://reactome.org/PathwayBrowser/#/R-DDI-379395 MAOA:FAD deaminates 3MT to HVA IEA Dictyostelium discoideum 15377 R-DDI-382560 https://reactome.org/PathwayBrowser/#/R-DDI-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Dictyostelium discoideum 15377 R-DDI-382575 https://reactome.org/PathwayBrowser/#/R-DDI-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Dictyostelium discoideum 15377 R-DDI-383190 https://reactome.org/PathwayBrowser/#/R-DDI-383190 HCO3- transport through ion channel IEA Dictyostelium discoideum 15377 R-DDI-389821 https://reactome.org/PathwayBrowser/#/R-DDI-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Dictyostelium discoideum 15377 R-DDI-389862 https://reactome.org/PathwayBrowser/#/R-DDI-389862 Conversion of glyoxylate to oxalate IEA Dictyostelium discoideum 15377 R-DDI-389986 https://reactome.org/PathwayBrowser/#/R-DDI-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-390252 https://reactome.org/PathwayBrowser/#/R-DDI-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-390329 https://reactome.org/PathwayBrowser/#/R-DDI-390329 Dephosphorylation of AKT by PP2A IEA Dictyostelium discoideum 15377 R-DDI-399998 https://reactome.org/PathwayBrowser/#/R-DDI-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Dictyostelium discoideum 15377 R-DDI-418553 https://reactome.org/PathwayBrowser/#/R-DDI-418553 cAMP degradation by Phosphodiesterases IEA Dictyostelium discoideum 15377 R-DDI-426043 https://reactome.org/PathwayBrowser/#/R-DDI-426043 2-AG hydrolysis to arachidonate by MAGL IEA Dictyostelium discoideum 15377 R-DDI-428259 https://reactome.org/PathwayBrowser/#/R-DDI-428259 DEGS1 dehydrogenates dihydroceramide IEA Dictyostelium discoideum 15377 R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 15377 R-DDI-428262 https://reactome.org/PathwayBrowser/#/R-DDI-428262 ACER3 hydrolyzes phytoceramide IEA Dictyostelium discoideum 15377 R-DDI-428664 https://reactome.org/PathwayBrowser/#/R-DDI-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Dictyostelium discoideum 15377 R-DDI-428690 https://reactome.org/PathwayBrowser/#/R-DDI-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Dictyostelium discoideum 15377 R-DDI-428696 https://reactome.org/PathwayBrowser/#/R-DDI-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Dictyostelium discoideum 15377 R-DDI-429157 https://reactome.org/PathwayBrowser/#/R-DDI-429157 ABCC4 accumulation of dense granule contents IEA Dictyostelium discoideum 15377 R-DDI-429860 https://reactome.org/PathwayBrowser/#/R-DDI-429860 DCP1-DCP2 complex decaps mRNA IEA Dictyostelium discoideum 15377 R-DDI-430028 https://reactome.org/PathwayBrowser/#/R-DDI-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Dictyostelium discoideum 15377 R-DDI-432010 https://reactome.org/PathwayBrowser/#/R-DDI-432010 Aquaporin-1 passively transports water into cell IEA Dictyostelium discoideum 15377 R-DDI-432054 https://reactome.org/PathwayBrowser/#/R-DDI-432054 Aquaporin-1 passively transports water out of cell IEA Dictyostelium discoideum 15377 R-DDI-432065 https://reactome.org/PathwayBrowser/#/R-DDI-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Dictyostelium discoideum 15377 R-DDI-432067 https://reactome.org/PathwayBrowser/#/R-DDI-432067 Aquaporin-4 passively transports water out of cell IEA Dictyostelium discoideum 15377 R-DDI-446200 https://reactome.org/PathwayBrowser/#/R-DDI-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Dictyostelium discoideum 15377 R-DDI-449937 https://reactome.org/PathwayBrowser/#/R-DDI-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Dictyostelium discoideum 15377 R-DDI-452036 https://reactome.org/PathwayBrowser/#/R-DDI-452036 arginine + H2O => ornithine + urea [ARG2] IEA Dictyostelium discoideum 15377 R-DDI-504054 https://reactome.org/PathwayBrowser/#/R-DDI-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Dictyostelium discoideum 15377 R-DDI-507868 https://reactome.org/PathwayBrowser/#/R-DDI-507868 Aquaporins passively transport water into cells IEA Dictyostelium discoideum 15377 R-DDI-507870 https://reactome.org/PathwayBrowser/#/R-DDI-507870 Aquaporins passively transport water out of cells IEA Dictyostelium discoideum 15377 R-DDI-508308 https://reactome.org/PathwayBrowser/#/R-DDI-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Dictyostelium discoideum 15377 R-DDI-5221130 https://reactome.org/PathwayBrowser/#/R-DDI-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Dictyostelium discoideum 15377 R-DDI-5223313 https://reactome.org/PathwayBrowser/#/R-DDI-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Dictyostelium discoideum 15377 R-DDI-5251955 https://reactome.org/PathwayBrowser/#/R-DDI-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Dictyostelium discoideum 15377 R-DDI-5251959 https://reactome.org/PathwayBrowser/#/R-DDI-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Dictyostelium discoideum 15377 R-DDI-5251989 https://reactome.org/PathwayBrowser/#/R-DDI-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Dictyostelium discoideum 15377 R-DDI-5362522 https://reactome.org/PathwayBrowser/#/R-DDI-5362522 ALDHs oxidise atRAL to atRA IEA Dictyostelium discoideum 15377 R-DDI-5423647 https://reactome.org/PathwayBrowser/#/R-DDI-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Dictyostelium discoideum 15377 R-DDI-5433074 https://reactome.org/PathwayBrowser/#/R-DDI-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Dictyostelium discoideum 15377 R-DDI-5603114 https://reactome.org/PathwayBrowser/#/R-DDI-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Dictyostelium discoideum 15377 R-DDI-5607735 https://reactome.org/PathwayBrowser/#/R-DDI-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Dictyostelium discoideum 15377 R-DDI-5631885 https://reactome.org/PathwayBrowser/#/R-DDI-5631885 PRDX1 overoxidizes IEA Dictyostelium discoideum 15377 R-DDI-5649705 https://reactome.org/PathwayBrowser/#/R-DDI-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Dictyostelium discoideum 15377 R-DDI-5651828 https://reactome.org/PathwayBrowser/#/R-DDI-5651828 PARG dePARylates PARP1,PARP2 IEA Dictyostelium discoideum 15377 R-DDI-5659861 https://reactome.org/PathwayBrowser/#/R-DDI-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 15377 R-DDI-5662692 https://reactome.org/PathwayBrowser/#/R-DDI-5662692 Dopa is oxidized to dopaquinone by TYR IEA Dictyostelium discoideum 15377 R-DDI-5675373 https://reactome.org/PathwayBrowser/#/R-DDI-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Dictyostelium discoideum 15377 R-DDI-5675376 https://reactome.org/PathwayBrowser/#/R-DDI-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Dictyostelium discoideum 15377 R-DDI-5676637 https://reactome.org/PathwayBrowser/#/R-DDI-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Dictyostelium discoideum 15377 R-DDI-5678327 https://reactome.org/PathwayBrowser/#/R-DDI-5678327 MIOX oxidises Ins to GlcA IEA Dictyostelium discoideum 15377 R-DDI-5678706 https://reactome.org/PathwayBrowser/#/R-DDI-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-5678863 https://reactome.org/PathwayBrowser/#/R-DDI-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-5679041 https://reactome.org/PathwayBrowser/#/R-DDI-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-5682285 https://reactome.org/PathwayBrowser/#/R-DDI-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-5683405 https://reactome.org/PathwayBrowser/#/R-DDI-5683405 PPP5C dephosphorylates TP53BP1 IEA Dictyostelium discoideum 15377 R-DDI-5683714 https://reactome.org/PathwayBrowser/#/R-DDI-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Dictyostelium discoideum 15377 R-DDI-5684864 https://reactome.org/PathwayBrowser/#/R-DDI-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Dictyostelium discoideum 15377 R-DDI-5688797 https://reactome.org/PathwayBrowser/#/R-DDI-5688797 ATXN3 family cleave Ub chains IEA Dictyostelium discoideum 15377 R-DDI-5689000 https://reactome.org/PathwayBrowser/#/R-DDI-5689000 AADAC deacetylates PHEN IEA Dictyostelium discoideum 15377 R-DDI-5689950 https://reactome.org/PathwayBrowser/#/R-DDI-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Dictyostelium discoideum 15377 R-DDI-5690043 https://reactome.org/PathwayBrowser/#/R-DDI-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 15377 R-DDI-5690046 https://reactome.org/PathwayBrowser/#/R-DDI-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Dictyostelium discoideum 15377 R-DDI-5690066 https://reactome.org/PathwayBrowser/#/R-DDI-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 15377 R-DDI-5690080 https://reactome.org/PathwayBrowser/#/R-DDI-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Dictyostelium discoideum 15377 R-DDI-5690152 https://reactome.org/PathwayBrowser/#/R-DDI-5690152 USP5 cleaves polyubiquitin IEA Dictyostelium discoideum 15377 R-DDI-5690157 https://reactome.org/PathwayBrowser/#/R-DDI-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Dictyostelium discoideum 15377 R-DDI-5690159 https://reactome.org/PathwayBrowser/#/R-DDI-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Dictyostelium discoideum 15377 R-DDI-5690319 https://reactome.org/PathwayBrowser/#/R-DDI-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Dictyostelium discoideum 15377 R-DDI-5690517 https://reactome.org/PathwayBrowser/#/R-DDI-5690517 PPT1 hydrolyses palmitoylated proteins IEA Dictyostelium discoideum 15377 R-DDI-5690565 https://reactome.org/PathwayBrowser/#/R-DDI-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15377 R-DDI-5690808 https://reactome.org/PathwayBrowser/#/R-DDI-5690808 UCHL3, SENP8 cleave NEDD8 IEA Dictyostelium discoideum 15377 R-DDI-5691381 https://reactome.org/PathwayBrowser/#/R-DDI-5691381 MYSM1 deubiquitinates Histone H2A IEA Dictyostelium discoideum 15377 R-DDI-5691512 https://reactome.org/PathwayBrowser/#/R-DDI-5691512 APEH hydrolyses NAc-Ser-protein IEA Dictyostelium discoideum 15377 R-DDI-5692261 https://reactome.org/PathwayBrowser/#/R-DDI-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Dictyostelium discoideum 15377 R-DDI-5692283 https://reactome.org/PathwayBrowser/#/R-DDI-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Dictyostelium discoideum 15377 R-DDI-5692462 https://reactome.org/PathwayBrowser/#/R-DDI-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Dictyostelium discoideum 15377 R-DDI-5692480 https://reactome.org/PathwayBrowser/#/R-DDI-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Dictyostelium discoideum 15377 R-DDI-5693346 https://reactome.org/PathwayBrowser/#/R-DDI-5693346 CECRI deaminates Ade-Rib to Ino IEA Dictyostelium discoideum 15377 R-DDI-5693691 https://reactome.org/PathwayBrowser/#/R-DDI-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Dictyostelium discoideum 15377 R-DDI-5693724 https://reactome.org/PathwayBrowser/#/R-DDI-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Dictyostelium discoideum 15377 R-DDI-5693761 https://reactome.org/PathwayBrowser/#/R-DDI-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Dictyostelium discoideum 15377 R-DDI-5693807 https://reactome.org/PathwayBrowser/#/R-DDI-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Dictyostelium discoideum 15377 R-DDI-5694137 https://reactome.org/PathwayBrowser/#/R-DDI-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Dictyostelium discoideum 15377 R-DDI-5694421 https://reactome.org/PathwayBrowser/#/R-DDI-5694421 PP6 dephosphorylates SEC24 IEA Dictyostelium discoideum 15377 R-DDI-5694485 https://reactome.org/PathwayBrowser/#/R-DDI-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Dictyostelium discoideum 15377 R-DDI-5696080 https://reactome.org/PathwayBrowser/#/R-DDI-5696080 ALDH3B1 oxidises HXAL to PALM IEA Dictyostelium discoideum 15377 R-DDI-5696091 https://reactome.org/PathwayBrowser/#/R-DDI-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Dictyostelium discoideum 15377 R-DDI-5696101 https://reactome.org/PathwayBrowser/#/R-DDI-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Dictyostelium discoideum 15377 R-DDI-5696119 https://reactome.org/PathwayBrowser/#/R-DDI-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Dictyostelium discoideum 15377 R-DDI-5696564 https://reactome.org/PathwayBrowser/#/R-DDI-5696564 USP25 deubiquitinates DDX58 IEA Dictyostelium discoideum 15377 R-DDI-5696600 https://reactome.org/PathwayBrowser/#/R-DDI-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Dictyostelium discoideum 15377 R-DDI-5696605 https://reactome.org/PathwayBrowser/#/R-DDI-5696605 USP12, USP26 deubiquitinate AR IEA Dictyostelium discoideum 15377 R-DDI-5696958 https://reactome.org/PathwayBrowser/#/R-DDI-5696958 USP44 deubiquitinates CDC20 IEA Dictyostelium discoideum 15377 R-DDI-5696960 https://reactome.org/PathwayBrowser/#/R-DDI-5696960 USP49 deubiquitinates H2B IEA Dictyostelium discoideum 15377 R-DDI-6781779 https://reactome.org/PathwayBrowser/#/R-DDI-6781779 USP13 deubiquitinates BECN1,USP10 IEA Dictyostelium discoideum 15377 R-DDI-6781814 https://reactome.org/PathwayBrowser/#/R-DDI-6781814 USP19 deubiquitinates RNF123 IEA Dictyostelium discoideum 15377 R-DDI-6782069 https://reactome.org/PathwayBrowser/#/R-DDI-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Dictyostelium discoideum 15377 R-DDI-6782820 https://reactome.org/PathwayBrowser/#/R-DDI-6782820 USP17 deubiquitinates SUDS3 IEA Dictyostelium discoideum 15377 R-DDI-6783177 https://reactome.org/PathwayBrowser/#/R-DDI-6783177 USP21 deubiquitinates GATA3,IL33 IEA Dictyostelium discoideum 15377 R-DDI-6783221 https://reactome.org/PathwayBrowser/#/R-DDI-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Dictyostelium discoideum 15377 R-DDI-6786650 https://reactome.org/PathwayBrowser/#/R-DDI-6786650 DDHD1,2 hydrolyse PA IEA Dictyostelium discoideum 15377 R-DDI-6787632 https://reactome.org/PathwayBrowser/#/R-DDI-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Dictyostelium discoideum 15377 R-DDI-6789031 https://reactome.org/PathwayBrowser/#/R-DDI-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 15377 R-DDI-6789126 https://reactome.org/PathwayBrowser/#/R-DDI-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 15377 R-DDI-6789310 https://reactome.org/PathwayBrowser/#/R-DDI-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Dictyostelium discoideum 15377 R-DDI-6797627 https://reactome.org/PathwayBrowser/#/R-DDI-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Dictyostelium discoideum 15377 R-DDI-6797630 https://reactome.org/PathwayBrowser/#/R-DDI-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Dictyostelium discoideum 15377 R-DDI-6797955 https://reactome.org/PathwayBrowser/#/R-DDI-6797955 ALDH7A1 oxidises BETALD to BET IEA Dictyostelium discoideum 15377 R-DDI-6799545 https://reactome.org/PathwayBrowser/#/R-DDI-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Dictyostelium discoideum 15377 R-DDI-6799581 https://reactome.org/PathwayBrowser/#/R-DDI-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Dictyostelium discoideum 15377 R-DDI-6799604 https://reactome.org/PathwayBrowser/#/R-DDI-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Dictyostelium discoideum 15377 R-DDI-6801462 https://reactome.org/PathwayBrowser/#/R-DDI-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Dictyostelium discoideum 15377 R-DDI-6807118 https://reactome.org/PathwayBrowser/#/R-DDI-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Dictyostelium discoideum 15377 R-DDI-6807206 https://reactome.org/PathwayBrowser/#/R-DDI-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Dictyostelium discoideum 15377 R-DDI-6808464 https://reactome.org/PathwayBrowser/#/R-DDI-6808464 ALDH3B2 oxidises HXAL to PALM IEA Dictyostelium discoideum 15377 R-DDI-6809287 https://reactome.org/PathwayBrowser/#/R-DDI-6809287 NUDT12 hydrolyses NADH to NMNH IEA Dictyostelium discoideum 15377 R-DDI-6809320 https://reactome.org/PathwayBrowser/#/R-DDI-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-6809325 https://reactome.org/PathwayBrowser/#/R-DDI-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-6809720 https://reactome.org/PathwayBrowser/#/R-DDI-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Dictyostelium discoideum 15377 R-DDI-6809777 https://reactome.org/PathwayBrowser/#/R-DDI-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Dictyostelium discoideum 15377 R-DDI-6809778 https://reactome.org/PathwayBrowser/#/R-DDI-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Dictyostelium discoideum 15377 R-DDI-6810076 https://reactome.org/PathwayBrowser/#/R-DDI-6810076 DDO oxidizes D-Asp to OA IEA Dictyostelium discoideum 15377 R-DDI-6810474 https://reactome.org/PathwayBrowser/#/R-DDI-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Dictyostelium discoideum 15377 R-DDI-6811504 https://reactome.org/PathwayBrowser/#/R-DDI-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Dictyostelium discoideum 15377 R-DDI-6813720 https://reactome.org/PathwayBrowser/#/R-DDI-6813720 NCEH1 hydrolyzes cholesterol esters IEA Dictyostelium discoideum 15377 R-DDI-6813749 https://reactome.org/PathwayBrowser/#/R-DDI-6813749 ALDH1A1 oxidises GA to DGA IEA Dictyostelium discoideum 15377 R-DDI-6814797 https://reactome.org/PathwayBrowser/#/R-DDI-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Dictyostelium discoideum 15377 R-DDI-70262 https://reactome.org/PathwayBrowser/#/R-DDI-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Dictyostelium discoideum 15377 R-DDI-70479 https://reactome.org/PathwayBrowser/#/R-DDI-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Dictyostelium discoideum 15377 R-DDI-70494 https://reactome.org/PathwayBrowser/#/R-DDI-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Dictyostelium discoideum 15377 R-DDI-70569 https://reactome.org/PathwayBrowser/#/R-DDI-70569 arginine + H2O => ornithine + urea [ARG1] IEA Dictyostelium discoideum 15377 R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Dictyostelium discoideum 15377 R-DDI-70599 https://reactome.org/PathwayBrowser/#/R-DDI-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Dictyostelium discoideum 15377 R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Dictyostelium discoideum 15377 R-DDI-70785 https://reactome.org/PathwayBrowser/#/R-DDI-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Dictyostelium discoideum 15377 R-DDI-70870 https://reactome.org/PathwayBrowser/#/R-DDI-70870 ECHS1 hydrates methacrylyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-70881 https://reactome.org/PathwayBrowser/#/R-DDI-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Dictyostelium discoideum 15377 R-DDI-70903 https://reactome.org/PathwayBrowser/#/R-DDI-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Dictyostelium discoideum 15377 R-DDI-70906 https://reactome.org/PathwayBrowser/#/R-DDI-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Dictyostelium discoideum 15377 R-DDI-70938 https://reactome.org/PathwayBrowser/#/R-DDI-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Dictyostelium discoideum 15377 R-DDI-70940 https://reactome.org/PathwayBrowser/#/R-DDI-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Dictyostelium discoideum 15377 R-DDI-70941 https://reactome.org/PathwayBrowser/#/R-DDI-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Dictyostelium discoideum 15377 R-DDI-70975 https://reactome.org/PathwayBrowser/#/R-DDI-70975 CS acetylates OA to citrate IEA Dictyostelium discoideum 15377 R-DDI-70982 https://reactome.org/PathwayBrowser/#/R-DDI-70982 FH tetramer hydrates fumarate to L-malate IEA Dictyostelium discoideum 15377 R-DDI-71146 https://reactome.org/PathwayBrowser/#/R-DDI-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Dictyostelium discoideum 15377 R-DDI-71181 https://reactome.org/PathwayBrowser/#/R-DDI-71181 FAH cleaves 4FAA IEA Dictyostelium discoideum 15377 R-DDI-71200 https://reactome.org/PathwayBrowser/#/R-DDI-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Dictyostelium discoideum 15377 R-DDI-71217 https://reactome.org/PathwayBrowser/#/R-DDI-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Dictyostelium discoideum 15377 R-DDI-71296 https://reactome.org/PathwayBrowser/#/R-DDI-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Dictyostelium discoideum 15377 R-DDI-71660 https://reactome.org/PathwayBrowser/#/R-DDI-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Dictyostelium discoideum 15377 R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 15377 R-DDI-71723 https://reactome.org/PathwayBrowser/#/R-DDI-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Dictyostelium discoideum 15377 R-DDI-71732 https://reactome.org/PathwayBrowser/#/R-DDI-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Dictyostelium discoideum 15377 R-DDI-73571 https://reactome.org/PathwayBrowser/#/R-DDI-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Dictyostelium discoideum 15377 R-DDI-73577 https://reactome.org/PathwayBrowser/#/R-DDI-73577 CAD hexamer transforms L-Gln to CAP IEA Dictyostelium discoideum 15377 R-DDI-73589 https://reactome.org/PathwayBrowser/#/R-DDI-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Dictyostelium discoideum 15377 R-DDI-73591 https://reactome.org/PathwayBrowser/#/R-DDI-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Dictyostelium discoideum 15377 R-DDI-73608 https://reactome.org/PathwayBrowser/#/R-DDI-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Dictyostelium discoideum 15377 R-DDI-73618 https://reactome.org/PathwayBrowser/#/R-DDI-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Dictyostelium discoideum 15377 R-DDI-73620 https://reactome.org/PathwayBrowser/#/R-DDI-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Dictyostelium discoideum 15377 R-DDI-73647 https://reactome.org/PathwayBrowser/#/R-DDI-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Dictyostelium discoideum 15377 R-DDI-73666 https://reactome.org/PathwayBrowser/#/R-DDI-73666 dUTP + H2O => dUMP + pyrophosphate IEA Dictyostelium discoideum 15377 R-DDI-73792 https://reactome.org/PathwayBrowser/#/R-DDI-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Dictyostelium discoideum 15377 R-DDI-73794 https://reactome.org/PathwayBrowser/#/R-DDI-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Dictyostelium discoideum 15377 R-DDI-73797 https://reactome.org/PathwayBrowser/#/R-DDI-73797 FAICAR => IMP + H2O IEA Dictyostelium discoideum 15377 R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 15377 R-DDI-74241 https://reactome.org/PathwayBrowser/#/R-DDI-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Dictyostelium discoideum 15377 R-DDI-74247 https://reactome.org/PathwayBrowser/#/R-DDI-74247 XDH oxidizes hypoxanthine to form xanthine IEA Dictyostelium discoideum 15377 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 15377 R-DDI-74255 https://reactome.org/PathwayBrowser/#/R-DDI-74255 Guanine + H2O => Xanthine + NH4+ IEA Dictyostelium discoideum 15377 R-DDI-74258 https://reactome.org/PathwayBrowser/#/R-DDI-74258 XDH oxidizes xanthine to form urate IEA Dictyostelium discoideum 15377 R-DDI-75872 https://reactome.org/PathwayBrowser/#/R-DDI-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Dictyostelium discoideum 15377 R-DDI-75899 https://reactome.org/PathwayBrowser/#/R-DDI-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Dictyostelium discoideum 15377 R-DDI-76031 https://reactome.org/PathwayBrowser/#/R-DDI-76031 2 H2O2 => O2 + 2 H2O IEA Dictyostelium discoideum 15377 R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 15377 R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 15377 R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 15377 R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 15377 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 15377 R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 15377 R-DDI-76590 https://reactome.org/PathwayBrowser/#/R-DDI-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Dictyostelium discoideum 15377 R-DDI-77256 https://reactome.org/PathwayBrowser/#/R-DDI-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-77314 https://reactome.org/PathwayBrowser/#/R-DDI-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-77325 https://reactome.org/PathwayBrowser/#/R-DDI-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-77333 https://reactome.org/PathwayBrowser/#/R-DDI-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-77344 https://reactome.org/PathwayBrowser/#/R-DDI-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Dictyostelium discoideum 15377 R-DDI-8847579 https://reactome.org/PathwayBrowser/#/R-DDI-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15377 R-DDI-8848053 https://reactome.org/PathwayBrowser/#/R-DDI-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Dictyostelium discoideum 15377 R-DDI-8848215 https://reactome.org/PathwayBrowser/#/R-DDI-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Dictyostelium discoideum 15377 R-DDI-8849969 https://reactome.org/PathwayBrowser/#/R-DDI-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Dictyostelium discoideum 15377 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 15377 R-DDI-8853686 https://reactome.org/PathwayBrowser/#/R-DDI-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Dictyostelium discoideum 15377 R-DDI-8854173 https://reactome.org/PathwayBrowser/#/R-DDI-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Dictyostelium discoideum 15377 R-DDI-8854255 https://reactome.org/PathwayBrowser/#/R-DDI-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 15377 R-DDI-8854329 https://reactome.org/PathwayBrowser/#/R-DDI-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 15377 R-DDI-8854604 https://reactome.org/PathwayBrowser/#/R-DDI-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Dictyostelium discoideum 15377 R-DDI-8854612 https://reactome.org/PathwayBrowser/#/R-DDI-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Dictyostelium discoideum 15377 R-DDI-8855490 https://reactome.org/PathwayBrowser/#/R-DDI-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Dictyostelium discoideum 15377 R-DDI-8856951 https://reactome.org/PathwayBrowser/#/R-DDI-8856951 PP2A demethylation by PPME1 IEA Dictyostelium discoideum 15377 R-DDI-8862320 https://reactome.org/PathwayBrowser/#/R-DDI-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Dictyostelium discoideum 15377 R-DDI-8866601 https://reactome.org/PathwayBrowser/#/R-DDI-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Dictyostelium discoideum 15377 R-DDI-8867344 https://reactome.org/PathwayBrowser/#/R-DDI-8867344 OMA1 hydrolyses OPA1 IEA Dictyostelium discoideum 15377 R-DDI-8874435 https://reactome.org/PathwayBrowser/#/R-DDI-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Dictyostelium discoideum 15377 R-DDI-8878581 https://reactome.org/PathwayBrowser/#/R-DDI-8878581 TYRP1 oxidises DHICA to IQCA IEA Dictyostelium discoideum 15377 R-DDI-8878654 https://reactome.org/PathwayBrowser/#/R-DDI-8878654 ACP6 hydrolyses MYS-LPA IEA Dictyostelium discoideum 15377 R-DDI-8933635 https://reactome.org/PathwayBrowser/#/R-DDI-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Dictyostelium discoideum 15377 R-DDI-8936442 https://reactome.org/PathwayBrowser/#/R-DDI-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Dictyostelium discoideum 15377 R-DDI-8937442 https://reactome.org/PathwayBrowser/#/R-DDI-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Dictyostelium discoideum 15377 R-DDI-8940388 https://reactome.org/PathwayBrowser/#/R-DDI-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Dictyostelium discoideum 15377 R-DDI-8952137 https://reactome.org/PathwayBrowser/#/R-DDI-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Dictyostelium discoideum 15377 R-DDI-8953499 https://reactome.org/PathwayBrowser/#/R-DDI-8953499 IMPAD1 hydrolyses PAP to AMP IEA Dictyostelium discoideum 15377 R-DDI-8954398 https://reactome.org/PathwayBrowser/#/R-DDI-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Dictyostelium discoideum 15377 R-DDI-8955817 https://reactome.org/PathwayBrowser/#/R-DDI-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Dictyostelium discoideum 15377 R-DDI-8957389 https://reactome.org/PathwayBrowser/#/R-DDI-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Dictyostelium discoideum 15377 R-DDI-8959510 https://reactome.org/PathwayBrowser/#/R-DDI-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Dictyostelium discoideum 15377 R-DDI-8979996 https://reactome.org/PathwayBrowser/#/R-DDI-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Dictyostelium discoideum 15377 R-DDI-9013144 https://reactome.org/PathwayBrowser/#/R-DDI-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Dictyostelium discoideum 15377 R-DDI-9013161 https://reactome.org/PathwayBrowser/#/R-DDI-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Dictyostelium discoideum 15377 R-DDI-9014295 https://reactome.org/PathwayBrowser/#/R-DDI-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Dictyostelium discoideum 15377 R-DDI-9014627 https://reactome.org/PathwayBrowser/#/R-DDI-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Dictyostelium discoideum 15377 R-DDI-9014741 https://reactome.org/PathwayBrowser/#/R-DDI-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Dictyostelium discoideum 15377 R-DDI-9017488 https://reactome.org/PathwayBrowser/#/R-DDI-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Dictyostelium discoideum 15377 R-DDI-9018745 https://reactome.org/PathwayBrowser/#/R-DDI-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Dictyostelium discoideum 15377 R-DDI-9018806 https://reactome.org/PathwayBrowser/#/R-DDI-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Dictyostelium discoideum 15377 R-DDI-9018814 https://reactome.org/PathwayBrowser/#/R-DDI-9018814 RHOT1 hydrolyzes GTP IEA Dictyostelium discoideum 15377 R-DDI-9018826 https://reactome.org/PathwayBrowser/#/R-DDI-9018826 RHOT2 hydrolyzes GTP IEA Dictyostelium discoideum 15377 R-DDI-9018862 https://reactome.org/PathwayBrowser/#/R-DDI-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Dictyostelium discoideum 15377 R-DDI-9018877 https://reactome.org/PathwayBrowser/#/R-DDI-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Dictyostelium discoideum 15377 R-DDI-9020252 https://reactome.org/PathwayBrowser/#/R-DDI-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Dictyostelium discoideum 15377 R-DDI-9020253 https://reactome.org/PathwayBrowser/#/R-DDI-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Dictyostelium discoideum 15377 R-DDI-9020257 https://reactome.org/PathwayBrowser/#/R-DDI-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Dictyostelium discoideum 15377 R-DDI-9020258 https://reactome.org/PathwayBrowser/#/R-DDI-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Dictyostelium discoideum 15377 R-DDI-9020270 https://reactome.org/PathwayBrowser/#/R-DDI-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Dictyostelium discoideum 15377 R-DDI-9024890 https://reactome.org/PathwayBrowser/#/R-DDI-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Dictyostelium discoideum 15377 R-DDI-9027043 https://reactome.org/PathwayBrowser/#/R-DDI-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Dictyostelium discoideum 15377 R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 15377 R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 15377 R-DDI-9033491 https://reactome.org/PathwayBrowser/#/R-DDI-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Dictyostelium discoideum 15377 R-DDI-9033520 https://reactome.org/PathwayBrowser/#/R-DDI-9033520 TYSND1 cleaves TYSND1 IEA Dictyostelium discoideum 15377 R-DDI-9034539 https://reactome.org/PathwayBrowser/#/R-DDI-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Dictyostelium discoideum 15377 R-DDI-9036727 https://reactome.org/PathwayBrowser/#/R-DDI-9036727 GAA hydrolyzes lysosomal glycogen IEA Dictyostelium discoideum 15377 R-DDI-917841 https://reactome.org/PathwayBrowser/#/R-DDI-917841 Acidification of Tf:TfR1 containing endosome IEA Dictyostelium discoideum 15377 R-DDI-917979 https://reactome.org/PathwayBrowser/#/R-DDI-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-936895 https://reactome.org/PathwayBrowser/#/R-DDI-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Dictyostelium discoideum 15377 R-DDI-939763 https://reactome.org/PathwayBrowser/#/R-DDI-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-947531 https://reactome.org/PathwayBrowser/#/R-DDI-947531 Molybdenum ion transfer onto molybdopterin IEA Dictyostelium discoideum 15377 R-DDI-947535 https://reactome.org/PathwayBrowser/#/R-DDI-947535 Cyclisation of GTP to precursor Z IEA Dictyostelium discoideum 15377 R-DDI-947591 https://reactome.org/PathwayBrowser/#/R-DDI-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Dictyostelium discoideum 15377 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 15377 R-DDI-9620103 https://reactome.org/PathwayBrowser/#/R-DDI-9620103 ALDH2 transforms GTN to NO IEA Dictyostelium discoideum 15377 R-DDI-9629675 https://reactome.org/PathwayBrowser/#/R-DDI-9629675 PDE3A hydrolyses cAMP to AMP IEA Dictyostelium discoideum 15377 R-DDI-9635739 https://reactome.org/PathwayBrowser/#/R-DDI-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Dictyostelium discoideum 15377 R-DDI-9638075 https://reactome.org/PathwayBrowser/#/R-DDI-9638075 HEXB cleaves the terminal GalNAc from DS IEA Dictyostelium discoideum 15377 R-DDI-9638076 https://reactome.org/PathwayBrowser/#/R-DDI-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Dictyostelium discoideum 15377 R-DDI-9638078 https://reactome.org/PathwayBrowser/#/R-DDI-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Dictyostelium discoideum 15377 R-DDI-9644869 https://reactome.org/PathwayBrowser/#/R-DDI-9644869 p-S54-PDE4B hydrolyses cAMP IEA Dictyostelium discoideum 15377 R-DDI-965079 https://reactome.org/PathwayBrowser/#/R-DDI-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Dictyostelium discoideum 15377 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 15377 R-DDI-9661417 https://reactome.org/PathwayBrowser/#/R-DDI-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-9668419 https://reactome.org/PathwayBrowser/#/R-DDI-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Dictyostelium discoideum 15377 R-DDI-9673053 https://reactome.org/PathwayBrowser/#/R-DDI-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Dictyostelium discoideum 15377 R-DDI-9673054 https://reactome.org/PathwayBrowser/#/R-DDI-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Dictyostelium discoideum 15377 R-DDI-9701565 https://reactome.org/PathwayBrowser/#/R-DDI-9701565 HDACs deacetylate p-STAT3 dimers IEA Dictyostelium discoideum 15377 R-DDI-9705507 https://reactome.org/PathwayBrowser/#/R-DDI-9705507 PDE3B hydrolyses cAMP to AMP IEA Dictyostelium discoideum 15377 R-DDI-9706399 https://reactome.org/PathwayBrowser/#/R-DDI-9706399 RHOBTB3 hydrolyzes ATP IEA Dictyostelium discoideum 15377 R-DDI-9708261 https://reactome.org/PathwayBrowser/#/R-DDI-9708261 PDE4A hydrolyses cAMP to AMP IEA Dictyostelium discoideum 15377 R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 15377 R-DDI-9727349 https://reactome.org/PathwayBrowser/#/R-DDI-9727349 XDH dehydrogenates xanthine to form urate IEA Dictyostelium discoideum 15377 R-DDI-9727567 https://reactome.org/PathwayBrowser/#/R-DDI-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Dictyostelium discoideum 15377 R-DDI-9748945 https://reactome.org/PathwayBrowser/#/R-DDI-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Dictyostelium discoideum 15377 R-DDI-9748957 https://reactome.org/PathwayBrowser/#/R-DDI-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Dictyostelium discoideum 15377 R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 15377 R-DDI-9749647 https://reactome.org/PathwayBrowser/#/R-DDI-9749647 CES2 hydrolyzes ASA- IEA Dictyostelium discoideum 15377 R-DDI-9749792 https://reactome.org/PathwayBrowser/#/R-DDI-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Dictyostelium discoideum 15377 R-DDI-9749986 https://reactome.org/PathwayBrowser/#/R-DDI-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Dictyostelium discoideum 15377 R-DDI-9750016 https://reactome.org/PathwayBrowser/#/R-DDI-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Dictyostelium discoideum 15377 R-DDI-9750546 https://reactome.org/PathwayBrowser/#/R-DDI-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-9750656 https://reactome.org/PathwayBrowser/#/R-DDI-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Dictyostelium discoideum 15377 R-DDI-9750942 https://reactome.org/PathwayBrowser/#/R-DDI-9750942 USP14 deubiquitinates NLRC5 IEA Dictyostelium discoideum 15377 R-DDI-9753278 https://reactome.org/PathwayBrowser/#/R-DDI-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 15377 R-DDI-9753280 https://reactome.org/PathwayBrowser/#/R-DDI-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Dictyostelium discoideum 15377 R-DDI-9753283 https://reactome.org/PathwayBrowser/#/R-DDI-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 15377 R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-9753285 https://reactome.org/PathwayBrowser/#/R-DDI-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Dictyostelium discoideum 15377 R-DDI-9753632 https://reactome.org/PathwayBrowser/#/R-DDI-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Dictyostelium discoideum 15377 R-DDI-9753944 https://reactome.org/PathwayBrowser/#/R-DDI-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Dictyostelium discoideum 15377 R-DDI-9754964 https://reactome.org/PathwayBrowser/#/R-DDI-9754964 ADA deamidates RBV IEA Dictyostelium discoideum 15377 R-DDI-9755030 https://reactome.org/PathwayBrowser/#/R-DDI-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Dictyostelium discoideum 15377 R-DDI-9755078 https://reactome.org/PathwayBrowser/#/R-DDI-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Dictyostelium discoideum 15377 R-DDI-9759206 https://reactome.org/PathwayBrowser/#/R-DDI-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Dictyostelium discoideum 15377 R-DDI-9759454 https://reactome.org/PathwayBrowser/#/R-DDI-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Dictyostelium discoideum 15377 R-DDI-9759461 https://reactome.org/PathwayBrowser/#/R-DDI-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Dictyostelium discoideum 15377 R-DDI-977324 https://reactome.org/PathwayBrowser/#/R-DDI-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Dictyostelium discoideum 15377 R-DDI-9794120 https://reactome.org/PathwayBrowser/#/R-DDI-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Dictyostelium discoideum 15377 R-DDI-9794572 https://reactome.org/PathwayBrowser/#/R-DDI-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Dictyostelium discoideum 15377 R-DDI-9837419 https://reactome.org/PathwayBrowser/#/R-DDI-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Dictyostelium discoideum 15377 R-DDI-9838004 https://reactome.org/PathwayBrowser/#/R-DDI-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Dictyostelium discoideum 15377 R-DDI-9838081 https://reactome.org/PathwayBrowser/#/R-DDI-9838081 LONP1 degrades mitochondrial matrix proteins IEA Dictyostelium discoideum 15377 R-DDI-9839105 https://reactome.org/PathwayBrowser/#/R-DDI-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Dictyostelium discoideum 15377 R-DDI-9839113 https://reactome.org/PathwayBrowser/#/R-DDI-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Dictyostelium discoideum 15377 R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 15377 R-DDI-9843721 https://reactome.org/PathwayBrowser/#/R-DDI-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Dictyostelium discoideum 15377 R-DDI-9853385 https://reactome.org/PathwayBrowser/#/R-DDI-9853385 PPP1CC dephosphorylates PLK1 IEA Dictyostelium discoideum 15377 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 15377 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 15377 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 15377 R-DME-111751 https://reactome.org/PathwayBrowser/#/R-DME-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 15377 R-DME-111804 https://reactome.org/PathwayBrowser/#/R-DME-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 15377 R-DME-111879 https://reactome.org/PathwayBrowser/#/R-DME-111879 PIP2 hydrolysis IEA Drosophila melanogaster 15377 R-DME-111955 https://reactome.org/PathwayBrowser/#/R-DME-111955 cAMP hydrolysis by Cam-PDE 1 IEA Drosophila melanogaster 15377 R-DME-111962 https://reactome.org/PathwayBrowser/#/R-DME-111962 PDE4A,C,D hydrolyse cAMP IEA Drosophila melanogaster 15377 R-DME-112037 https://reactome.org/PathwayBrowser/#/R-DME-112037 Inactivation of PLC beta IEA Drosophila melanogaster 15377 R-DME-1237045 https://reactome.org/PathwayBrowser/#/R-DME-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Drosophila melanogaster 15377 R-DME-1237047 https://reactome.org/PathwayBrowser/#/R-DME-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Drosophila melanogaster 15377 R-DME-1237059 https://reactome.org/PathwayBrowser/#/R-DME-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Drosophila melanogaster 15377 R-DME-1237081 https://reactome.org/PathwayBrowser/#/R-DME-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Drosophila melanogaster 15377 R-DME-1237129 https://reactome.org/PathwayBrowser/#/R-DME-1237129 Acireductone is created IEA Drosophila melanogaster 15377 R-DME-1247910 https://reactome.org/PathwayBrowser/#/R-DME-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Drosophila melanogaster 15377 R-DME-1247935 https://reactome.org/PathwayBrowser/#/R-DME-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Drosophila melanogaster 15377 R-DME-1363274 https://reactome.org/PathwayBrowser/#/R-DME-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Drosophila melanogaster 15377 R-DME-1363276 https://reactome.org/PathwayBrowser/#/R-DME-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Drosophila melanogaster 15377 R-DME-1369065 https://reactome.org/PathwayBrowser/#/R-DME-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Drosophila melanogaster 15377 R-DME-141341 https://reactome.org/PathwayBrowser/#/R-DME-141341 SMOX-3 oxidises SPN to SPM IEA Drosophila melanogaster 15377 R-DME-141348 https://reactome.org/PathwayBrowser/#/R-DME-141348 PAO:FAD oxidises NASPM to PTCN IEA Drosophila melanogaster 15377 R-DME-141351 https://reactome.org/PathwayBrowser/#/R-DME-141351 PAOX:FAD oxidises NASPN to SPM IEA Drosophila melanogaster 15377 R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 15377 R-DME-1454916 https://reactome.org/PathwayBrowser/#/R-DME-1454916 The ABCC family mediates organic anion transport IEA Drosophila melanogaster 15377 R-DME-1454928 https://reactome.org/PathwayBrowser/#/R-DME-1454928 ABCG4 may mediate cholesterol efflux IEA Drosophila melanogaster 15377 R-DME-1467466 https://reactome.org/PathwayBrowser/#/R-DME-1467466 ABCA4 mediates atRAL transport IEA Drosophila melanogaster 15377 R-DME-1474146 https://reactome.org/PathwayBrowser/#/R-DME-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Drosophila melanogaster 15377 R-DME-1475017 https://reactome.org/PathwayBrowser/#/R-DME-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Drosophila melanogaster 15377 R-DME-1475022 https://reactome.org/PathwayBrowser/#/R-DME-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Drosophila melanogaster 15377 R-DME-1475025 https://reactome.org/PathwayBrowser/#/R-DME-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Drosophila melanogaster 15377 R-DME-1475026 https://reactome.org/PathwayBrowser/#/R-DME-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Drosophila melanogaster 15377 R-DME-1475028 https://reactome.org/PathwayBrowser/#/R-DME-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Drosophila melanogaster 15377 R-DME-1475032 https://reactome.org/PathwayBrowser/#/R-DME-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Drosophila melanogaster 15377 R-DME-1475435 https://reactome.org/PathwayBrowser/#/R-DME-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Drosophila melanogaster 15377 R-DME-1475436 https://reactome.org/PathwayBrowser/#/R-DME-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Drosophila melanogaster 15377 R-DME-1482604 https://reactome.org/PathwayBrowser/#/R-DME-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Drosophila melanogaster 15377 R-DME-1482656 https://reactome.org/PathwayBrowser/#/R-DME-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Drosophila melanogaster 15377 R-DME-1482679 https://reactome.org/PathwayBrowser/#/R-DME-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Drosophila melanogaster 15377 R-DME-1482776 https://reactome.org/PathwayBrowser/#/R-DME-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Drosophila melanogaster 15377 R-DME-1482777 https://reactome.org/PathwayBrowser/#/R-DME-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Drosophila melanogaster 15377 R-DME-1482811 https://reactome.org/PathwayBrowser/#/R-DME-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Drosophila melanogaster 15377 R-DME-1482816 https://reactome.org/PathwayBrowser/#/R-DME-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Drosophila melanogaster 15377 R-DME-1482856 https://reactome.org/PathwayBrowser/#/R-DME-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Drosophila melanogaster 15377 R-DME-1482868 https://reactome.org/PathwayBrowser/#/R-DME-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Drosophila melanogaster 15377 R-DME-1482884 https://reactome.org/PathwayBrowser/#/R-DME-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Drosophila melanogaster 15377 R-DME-1482887 https://reactome.org/PathwayBrowser/#/R-DME-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Drosophila melanogaster 15377 R-DME-1482900 https://reactome.org/PathwayBrowser/#/R-DME-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Drosophila melanogaster 15377 R-DME-1482907 https://reactome.org/PathwayBrowser/#/R-DME-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Drosophila melanogaster 15377 R-DME-1483096 https://reactome.org/PathwayBrowser/#/R-DME-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Drosophila melanogaster 15377 R-DME-1483159 https://reactome.org/PathwayBrowser/#/R-DME-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Drosophila melanogaster 15377 R-DME-1483182 https://reactome.org/PathwayBrowser/#/R-DME-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Drosophila melanogaster 15377 R-DME-1483203 https://reactome.org/PathwayBrowser/#/R-DME-1483203 PA is dephosphorylated to DAG by LPIN IEA Drosophila melanogaster 15377 R-DME-156526 https://reactome.org/PathwayBrowser/#/R-DME-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Drosophila melanogaster 15377 R-DME-159425 https://reactome.org/PathwayBrowser/#/R-DME-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 15377 R-DME-1602368 https://reactome.org/PathwayBrowser/#/R-DME-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Drosophila melanogaster 15377 R-DME-1602374 https://reactome.org/PathwayBrowser/#/R-DME-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Drosophila melanogaster 15377 R-DME-1602377 https://reactome.org/PathwayBrowser/#/R-DME-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Drosophila melanogaster 15377 R-DME-1602398 https://reactome.org/PathwayBrowser/#/R-DME-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Drosophila melanogaster 15377 R-DME-1602399 https://reactome.org/PathwayBrowser/#/R-DME-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Drosophila melanogaster 15377 R-DME-1602417 https://reactome.org/PathwayBrowser/#/R-DME-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Drosophila melanogaster 15377 R-DME-1602446 https://reactome.org/PathwayBrowser/#/R-DME-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Drosophila melanogaster 15377 R-DME-1605591 https://reactome.org/PathwayBrowser/#/R-DME-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Drosophila melanogaster 15377 R-DME-1605624 https://reactome.org/PathwayBrowser/#/R-DME-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Drosophila melanogaster 15377 R-DME-1605632 https://reactome.org/PathwayBrowser/#/R-DME-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Drosophila melanogaster 15377 R-DME-1605797 https://reactome.org/PathwayBrowser/#/R-DME-1605797 SMPD1 hydrolyzes SPHM IEA Drosophila melanogaster 15377 R-DME-1606273 https://reactome.org/PathwayBrowser/#/R-DME-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Drosophila melanogaster 15377 R-DME-1606288 https://reactome.org/PathwayBrowser/#/R-DME-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Drosophila melanogaster 15377 R-DME-1606312 https://reactome.org/PathwayBrowser/#/R-DME-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Drosophila melanogaster 15377 R-DME-1606583 https://reactome.org/PathwayBrowser/#/R-DME-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Drosophila melanogaster 15377 R-DME-1614524 https://reactome.org/PathwayBrowser/#/R-DME-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Drosophila melanogaster 15377 R-DME-1614544 https://reactome.org/PathwayBrowser/#/R-DME-1614544 Sulfite is oxidized to sulfate IEA Drosophila melanogaster 15377 R-DME-1614583 https://reactome.org/PathwayBrowser/#/R-DME-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Drosophila melanogaster 15377 R-DME-1614605 https://reactome.org/PathwayBrowser/#/R-DME-1614605 Persulfide sulfur is dioxygenated IEA Drosophila melanogaster 15377 R-DME-1614614 https://reactome.org/PathwayBrowser/#/R-DME-1614614 Cysteine is degraded to serine and H2S IEA Drosophila melanogaster 15377 R-DME-1614631 https://reactome.org/PathwayBrowser/#/R-DME-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Drosophila melanogaster 15377 R-DME-162857 https://reactome.org/PathwayBrowser/#/R-DME-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Drosophila melanogaster 15377 R-DME-1630306 https://reactome.org/PathwayBrowser/#/R-DME-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Drosophila melanogaster 15377 R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 15377 R-DME-1638032 https://reactome.org/PathwayBrowser/#/R-DME-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Drosophila melanogaster 15377 R-DME-1638053 https://reactome.org/PathwayBrowser/#/R-DME-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Drosophila melanogaster 15377 R-DME-164832 https://reactome.org/PathwayBrowser/#/R-DME-164832 ATPase synthesizes ATP IEA Drosophila melanogaster 15377 R-DME-1667005 https://reactome.org/PathwayBrowser/#/R-DME-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Drosophila melanogaster 15377 R-DME-1675795 https://reactome.org/PathwayBrowser/#/R-DME-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Drosophila melanogaster 15377 R-DME-1675824 https://reactome.org/PathwayBrowser/#/R-DME-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Drosophila melanogaster 15377 R-DME-1675836 https://reactome.org/PathwayBrowser/#/R-DME-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1675949 https://reactome.org/PathwayBrowser/#/R-DME-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1675988 https://reactome.org/PathwayBrowser/#/R-DME-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1675994 https://reactome.org/PathwayBrowser/#/R-DME-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1676065 https://reactome.org/PathwayBrowser/#/R-DME-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Drosophila melanogaster 15377 R-DME-1676105 https://reactome.org/PathwayBrowser/#/R-DME-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Drosophila melanogaster 15377 R-DME-1676114 https://reactome.org/PathwayBrowser/#/R-DME-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Drosophila melanogaster 15377 R-DME-1676124 https://reactome.org/PathwayBrowser/#/R-DME-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Drosophila melanogaster 15377 R-DME-1676141 https://reactome.org/PathwayBrowser/#/R-DME-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Drosophila melanogaster 15377 R-DME-1676149 https://reactome.org/PathwayBrowser/#/R-DME-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1676162 https://reactome.org/PathwayBrowser/#/R-DME-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Drosophila melanogaster 15377 R-DME-1676164 https://reactome.org/PathwayBrowser/#/R-DME-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1676177 https://reactome.org/PathwayBrowser/#/R-DME-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1676203 https://reactome.org/PathwayBrowser/#/R-DME-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1678650 https://reactome.org/PathwayBrowser/#/R-DME-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Drosophila melanogaster 15377 R-DME-1678708 https://reactome.org/PathwayBrowser/#/R-DME-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Drosophila melanogaster 15377 R-DME-1678716 https://reactome.org/PathwayBrowser/#/R-DME-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Drosophila melanogaster 15377 R-DME-1678742 https://reactome.org/PathwayBrowser/#/R-DME-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Drosophila melanogaster 15377 R-DME-1678854 https://reactome.org/PathwayBrowser/#/R-DME-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Drosophila melanogaster 15377 R-DME-170153 https://reactome.org/PathwayBrowser/#/R-DME-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Drosophila melanogaster 15377 R-DME-170158 https://reactome.org/PathwayBrowser/#/R-DME-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Drosophila melanogaster 15377 R-DME-170161 https://reactome.org/PathwayBrowser/#/R-DME-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Drosophila melanogaster 15377 R-DME-173597 https://reactome.org/PathwayBrowser/#/R-DME-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Drosophila melanogaster 15377 R-DME-174110 https://reactome.org/PathwayBrowser/#/R-DME-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Drosophila melanogaster 15377 R-DME-174124 https://reactome.org/PathwayBrowser/#/R-DME-174124 Dephosphorylation of phospho-Cdh1 IEA Drosophila melanogaster 15377 R-DME-174401 https://reactome.org/PathwayBrowser/#/R-DME-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Drosophila melanogaster 15377 R-DME-176606 https://reactome.org/PathwayBrowser/#/R-DME-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Drosophila melanogaster 15377 R-DME-177923 https://reactome.org/PathwayBrowser/#/R-DME-177923 Sustained activation of SRC kinase by SHP2 IEA Drosophila melanogaster 15377 R-DME-177924 https://reactome.org/PathwayBrowser/#/R-DME-177924 Dephosphorylation of Gab1 by SHP2 IEA Drosophila melanogaster 15377 R-DME-177935 https://reactome.org/PathwayBrowser/#/R-DME-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Drosophila melanogaster 15377 R-DME-1793182 https://reactome.org/PathwayBrowser/#/R-DME-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Drosophila melanogaster 15377 R-DME-1793186 https://reactome.org/PathwayBrowser/#/R-DME-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Drosophila melanogaster 15377 R-DME-1855154 https://reactome.org/PathwayBrowser/#/R-DME-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855165 https://reactome.org/PathwayBrowser/#/R-DME-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855166 https://reactome.org/PathwayBrowser/#/R-DME-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855174 https://reactome.org/PathwayBrowser/#/R-DME-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855177 https://reactome.org/PathwayBrowser/#/R-DME-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1855180 https://reactome.org/PathwayBrowser/#/R-DME-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855198 https://reactome.org/PathwayBrowser/#/R-DME-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855202 https://reactome.org/PathwayBrowser/#/R-DME-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855205 https://reactome.org/PathwayBrowser/#/R-DME-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855208 https://reactome.org/PathwayBrowser/#/R-DME-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855210 https://reactome.org/PathwayBrowser/#/R-DME-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855211 https://reactome.org/PathwayBrowser/#/R-DME-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855213 https://reactome.org/PathwayBrowser/#/R-DME-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1855214 https://reactome.org/PathwayBrowser/#/R-DME-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Drosophila melanogaster 15377 R-DME-1855218 https://reactome.org/PathwayBrowser/#/R-DME-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Drosophila melanogaster 15377 R-DME-1855221 https://reactome.org/PathwayBrowser/#/R-DME-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1855222 https://reactome.org/PathwayBrowser/#/R-DME-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-1855232 https://reactome.org/PathwayBrowser/#/R-DME-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Drosophila melanogaster 15377 R-DME-1861788 https://reactome.org/PathwayBrowser/#/R-DME-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Drosophila melanogaster 15377 R-DME-1861789 https://reactome.org/PathwayBrowser/#/R-DME-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Drosophila melanogaster 15377 R-DME-188979 https://reactome.org/PathwayBrowser/#/R-DME-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Drosophila melanogaster 15377 R-DME-189062 https://reactome.org/PathwayBrowser/#/R-DME-189062 lactose + H2O => D-glucose + D-galactose IEA Drosophila melanogaster 15377 R-DME-189398 https://reactome.org/PathwayBrowser/#/R-DME-189398 HMOX1 dimer, HMOX2 cleave heme IEA Drosophila melanogaster 15377 R-DME-189406 https://reactome.org/PathwayBrowser/#/R-DME-189406 4 PBGs bind to form HMB IEA Drosophila melanogaster 15377 R-DME-189421 https://reactome.org/PathwayBrowser/#/R-DME-189421 CPO transforms COPRO3 to PPGEN9 IEA Drosophila melanogaster 15377 R-DME-189439 https://reactome.org/PathwayBrowser/#/R-DME-189439 ALAD condenses 2 dALAs to form PBG IEA Drosophila melanogaster 15377 R-DME-189488 https://reactome.org/PathwayBrowser/#/R-DME-189488 UROS transforms HMB to URO3 IEA Drosophila melanogaster 15377 R-DME-191114 https://reactome.org/PathwayBrowser/#/R-DME-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Drosophila melanogaster 15377 R-DME-191323 https://reactome.org/PathwayBrowser/#/R-DME-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Drosophila melanogaster 15377 R-DME-192331 https://reactome.org/PathwayBrowser/#/R-DME-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Drosophila melanogaster 15377 R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 15377 R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 15377 R-DME-192430 https://reactome.org/PathwayBrowser/#/R-DME-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 15377 R-DME-192475 https://reactome.org/PathwayBrowser/#/R-DME-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Drosophila melanogaster 15377 R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 15377 R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 15377 R-DME-193535 https://reactome.org/PathwayBrowser/#/R-DME-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Drosophila melanogaster 15377 R-DME-193711 https://reactome.org/PathwayBrowser/#/R-DME-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 15377 R-DME-193727 https://reactome.org/PathwayBrowser/#/R-DME-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 15377 R-DME-193743 https://reactome.org/PathwayBrowser/#/R-DME-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 15377 R-DME-193766 https://reactome.org/PathwayBrowser/#/R-DME-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 15377 R-DME-197271 https://reactome.org/PathwayBrowser/#/R-DME-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Drosophila melanogaster 15377 R-DME-199425 https://reactome.org/PathwayBrowser/#/R-DME-199425 PHLPP dephosphorylates S473 in AKT IEA Drosophila melanogaster 15377 R-DME-199456 https://reactome.org/PathwayBrowser/#/R-DME-199456 PTEN dephosphorylates PIP3 IEA Drosophila melanogaster 15377 R-DME-199959 https://reactome.org/PathwayBrowser/#/R-DME-199959 ERKs are inactivated by protein phosphatase 2A IEA Drosophila melanogaster 15377 R-DME-200661 https://reactome.org/PathwayBrowser/#/R-DME-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Drosophila melanogaster 15377 R-DME-200740 https://reactome.org/PathwayBrowser/#/R-DME-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Drosophila melanogaster 15377 R-DME-201035 https://reactome.org/PathwayBrowser/#/R-DME-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Drosophila melanogaster 15377 R-DME-2022368 https://reactome.org/PathwayBrowser/#/R-DME-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Drosophila melanogaster 15377 R-DME-2022396 https://reactome.org/PathwayBrowser/#/R-DME-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Drosophila melanogaster 15377 R-DME-2022398 https://reactome.org/PathwayBrowser/#/R-DME-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Drosophila melanogaster 15377 R-DME-2022399 https://reactome.org/PathwayBrowser/#/R-DME-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Drosophila melanogaster 15377 R-DME-2022403 https://reactome.org/PathwayBrowser/#/R-DME-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Drosophila melanogaster 15377 R-DME-2022405 https://reactome.org/PathwayBrowser/#/R-DME-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 15377 R-DME-2022412 https://reactome.org/PathwayBrowser/#/R-DME-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Drosophila melanogaster 15377 R-DME-2022887 https://reactome.org/PathwayBrowser/#/R-DME-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Drosophila melanogaster 15377 R-DME-2023971 https://reactome.org/PathwayBrowser/#/R-DME-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 15377 R-DME-2023973 https://reactome.org/PathwayBrowser/#/R-DME-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 15377 R-DME-202407 https://reactome.org/PathwayBrowser/#/R-DME-202407 PLC-gamma1 hydrolyses PIP2 IEA Drosophila melanogaster 15377 R-DME-2028294 https://reactome.org/PathwayBrowser/#/R-DME-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Drosophila melanogaster 15377 R-DME-2029468 https://reactome.org/PathwayBrowser/#/R-DME-2029468 Conversion of PA into DAG by PAP-1 IEA Drosophila melanogaster 15377 R-DME-2029471 https://reactome.org/PathwayBrowser/#/R-DME-2029471 Hydrolysis of PC to PA by PLD IEA Drosophila melanogaster 15377 R-DME-2029475 https://reactome.org/PathwayBrowser/#/R-DME-2029475 Production of AA by iPLA2 upon FCGR activation IEA Drosophila melanogaster 15377 R-DME-203797 https://reactome.org/PathwayBrowser/#/R-DME-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Drosophila melanogaster 15377 R-DME-204169 https://reactome.org/PathwayBrowser/#/R-DME-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Drosophila melanogaster 15377 R-DME-2046083 https://reactome.org/PathwayBrowser/#/R-DME-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Drosophila melanogaster 15377 R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster 15377 R-DME-2046090 https://reactome.org/PathwayBrowser/#/R-DME-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Drosophila melanogaster 15377 R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster 15377 R-DME-2046095 https://reactome.org/PathwayBrowser/#/R-DME-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Drosophila melanogaster 15377 R-DME-2046100 https://reactome.org/PathwayBrowser/#/R-DME-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Drosophila melanogaster 15377 R-DME-204662 https://reactome.org/PathwayBrowser/#/R-DME-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Drosophila melanogaster 15377 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 15377 R-DME-2065357 https://reactome.org/PathwayBrowser/#/R-DME-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Drosophila melanogaster 15377 R-DME-2066778 https://reactome.org/PathwayBrowser/#/R-DME-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Drosophila melanogaster 15377 R-DME-2090037 https://reactome.org/PathwayBrowser/#/R-DME-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Drosophila melanogaster 15377 R-DME-2090038 https://reactome.org/PathwayBrowser/#/R-DME-2090038 NAGLU hydrolyses heparan chain(2) IEA Drosophila melanogaster 15377 R-DME-2090043 https://reactome.org/PathwayBrowser/#/R-DME-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Drosophila melanogaster 15377 R-DME-2090079 https://reactome.org/PathwayBrowser/#/R-DME-2090079 GLB1 hydrolyses linker chain(2) IEA Drosophila melanogaster 15377 R-DME-209055 https://reactome.org/PathwayBrowser/#/R-DME-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Drosophila melanogaster 15377 R-DME-209845 https://reactome.org/PathwayBrowser/#/R-DME-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Drosophila melanogaster 15377 R-DME-209891 https://reactome.org/PathwayBrowser/#/R-DME-209891 Dopamine is oxidised to noradrenaline IEA Drosophila melanogaster 15377 R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 15377 R-DME-2105001 https://reactome.org/PathwayBrowser/#/R-DME-2105001 HEXA cleaves the terminal GalNAc from DS IEA Drosophila melanogaster 15377 R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 15377 R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 15377 R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 15377 R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 15377 R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 15377 R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 15377 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 15377 R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 15377 R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 15377 R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 15377 R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 15377 R-DME-2161187 https://reactome.org/PathwayBrowser/#/R-DME-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Drosophila melanogaster 15377 R-DME-2161195 https://reactome.org/PathwayBrowser/#/R-DME-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Drosophila melanogaster 15377 R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 15377 R-DME-2161890 https://reactome.org/PathwayBrowser/#/R-DME-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Drosophila melanogaster 15377 R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Drosophila melanogaster 15377 R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 15377 R-DME-2162225 https://reactome.org/PathwayBrowser/#/R-DME-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Drosophila melanogaster 15377 R-DME-2162226 https://reactome.org/PathwayBrowser/#/R-DME-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Drosophila melanogaster 15377 R-DME-2162227 https://reactome.org/PathwayBrowser/#/R-DME-2162227 GUSB tetramer hydrolyses (HA)2 IEA Drosophila melanogaster 15377 R-DME-2187401 https://reactome.org/PathwayBrowser/#/R-DME-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Drosophila melanogaster 15377 R-DME-2393954 https://reactome.org/PathwayBrowser/#/R-DME-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Drosophila melanogaster 15377 R-DME-2395873 https://reactome.org/PathwayBrowser/#/R-DME-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Drosophila melanogaster 15377 R-DME-2395879 https://reactome.org/PathwayBrowser/#/R-DME-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Drosophila melanogaster 15377 R-DME-2395965 https://reactome.org/PathwayBrowser/#/R-DME-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Drosophila melanogaster 15377 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 15377 R-DME-2509827 https://reactome.org/PathwayBrowser/#/R-DME-2509827 ITPA hydrolyses ITP to IMP IEA Drosophila melanogaster 15377 R-DME-2509831 https://reactome.org/PathwayBrowser/#/R-DME-2509831 ITPA hydrolyses XTP to XMP IEA Drosophila melanogaster 15377 R-DME-2509838 https://reactome.org/PathwayBrowser/#/R-DME-2509838 ITPA hydrolyses dITP to dIMP IEA Drosophila melanogaster 15377 R-DME-2529015 https://reactome.org/PathwayBrowser/#/R-DME-2529015 Dephosphorylation of CK2-modified condensin I IEA Drosophila melanogaster 15377 R-DME-265783 https://reactome.org/PathwayBrowser/#/R-DME-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-DME-266012 https://reactome.org/PathwayBrowser/#/R-DME-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Drosophila melanogaster 15377 R-DME-266046 https://reactome.org/PathwayBrowser/#/R-DME-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Drosophila melanogaster 15377 R-DME-266072 https://reactome.org/PathwayBrowser/#/R-DME-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Drosophila melanogaster 15377 R-DME-266082 https://reactome.org/PathwayBrowser/#/R-DME-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Drosophila melanogaster 15377 R-DME-2730847 https://reactome.org/PathwayBrowser/#/R-DME-2730847 Hydrolysis of PIP2 by PLCG IEA Drosophila melanogaster 15377 R-DME-2730849 https://reactome.org/PathwayBrowser/#/R-DME-2730849 Calcineurin binds and dephosphorylates NFAT IEA Drosophila melanogaster 15377 R-DME-2995330 https://reactome.org/PathwayBrowser/#/R-DME-2995330 COX10 transforms heme to heme O IEA Drosophila melanogaster 15377 R-DME-2995334 https://reactome.org/PathwayBrowser/#/R-DME-2995334 COX15 transforms heme O to heme A IEA Drosophila melanogaster 15377 R-DME-2995388 https://reactome.org/PathwayBrowser/#/R-DME-2995388 PP2A dephosphorylates BANF1 IEA Drosophila melanogaster 15377 R-DME-3002811 https://reactome.org/PathwayBrowser/#/R-DME-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Drosophila melanogaster 15377 R-DME-3095901 https://reactome.org/PathwayBrowser/#/R-DME-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Drosophila melanogaster 15377 R-DME-3204311 https://reactome.org/PathwayBrowser/#/R-DME-3204311 AOX1 oxidises PXL to PDXate IEA Drosophila melanogaster 15377 R-DME-3215310 https://reactome.org/PathwayBrowser/#/R-DME-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Drosophila melanogaster 15377 R-DME-3262512 https://reactome.org/PathwayBrowser/#/R-DME-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Drosophila melanogaster 15377 R-DME-3266566 https://reactome.org/PathwayBrowser/#/R-DME-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Drosophila melanogaster 15377 R-DME-3322995 https://reactome.org/PathwayBrowser/#/R-DME-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Drosophila melanogaster 15377 R-DME-3341343 https://reactome.org/PathwayBrowser/#/R-DME-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Drosophila melanogaster 15377 R-DME-350901 https://reactome.org/PathwayBrowser/#/R-DME-350901 Iodide is organified IEA Drosophila melanogaster 15377 R-DME-3697882 https://reactome.org/PathwayBrowser/#/R-DME-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Drosophila melanogaster 15377 R-DME-3697894 https://reactome.org/PathwayBrowser/#/R-DME-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Drosophila melanogaster 15377 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 15377 R-DME-3769447 https://reactome.org/PathwayBrowser/#/R-DME-3769447 HDAC1:2-containing complex deacetylate histones IEA Drosophila melanogaster 15377 R-DME-377643 https://reactome.org/PathwayBrowser/#/R-DME-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Drosophila melanogaster 15377 R-DME-3777129 https://reactome.org/PathwayBrowser/#/R-DME-3777129 HDAC3 containing complexes deacetylate histone IEA Drosophila melanogaster 15377 R-DME-3781011 https://reactome.org/PathwayBrowser/#/R-DME-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Drosophila melanogaster 15377 R-DME-3781018 https://reactome.org/PathwayBrowser/#/R-DME-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Drosophila melanogaster 15377 R-DME-3782655 https://reactome.org/PathwayBrowser/#/R-DME-3782655 HDAC10 deacetylates histone IEA Drosophila melanogaster 15377 R-DME-380949 https://reactome.org/PathwayBrowser/#/R-DME-380949 AMPK is dephosphorylated IEA Drosophila melanogaster 15377 R-DME-382560 https://reactome.org/PathwayBrowser/#/R-DME-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Drosophila melanogaster 15377 R-DME-382575 https://reactome.org/PathwayBrowser/#/R-DME-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Drosophila melanogaster 15377 R-DME-383190 https://reactome.org/PathwayBrowser/#/R-DME-383190 HCO3- transport through ion channel IEA Drosophila melanogaster 15377 R-DME-389821 https://reactome.org/PathwayBrowser/#/R-DME-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Drosophila melanogaster 15377 R-DME-389862 https://reactome.org/PathwayBrowser/#/R-DME-389862 Conversion of glyoxylate to oxalate IEA Drosophila melanogaster 15377 R-DME-389986 https://reactome.org/PathwayBrowser/#/R-DME-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Drosophila melanogaster 15377 R-DME-390252 https://reactome.org/PathwayBrowser/#/R-DME-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Drosophila melanogaster 15377 R-DME-390329 https://reactome.org/PathwayBrowser/#/R-DME-390329 Dephosphorylation of AKT by PP2A IEA Drosophila melanogaster 15377 R-DME-399998 https://reactome.org/PathwayBrowser/#/R-DME-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Drosophila melanogaster 15377 R-DME-4084976 https://reactome.org/PathwayBrowser/#/R-DME-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Drosophila melanogaster 15377 R-DME-4084989 https://reactome.org/PathwayBrowser/#/R-DME-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Drosophila melanogaster 15377 R-DME-4093339 https://reactome.org/PathwayBrowser/#/R-DME-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Drosophila melanogaster 15377 R-DME-418553 https://reactome.org/PathwayBrowser/#/R-DME-418553 cAMP degradation by Phosphodiesterases IEA Drosophila melanogaster 15377 R-DME-428205 https://reactome.org/PathwayBrowser/#/R-DME-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Drosophila melanogaster 15377 R-DME-428231 https://reactome.org/PathwayBrowser/#/R-DME-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Drosophila melanogaster 15377 R-DME-428259 https://reactome.org/PathwayBrowser/#/R-DME-428259 DEGS1 dehydrogenates dihydroceramide IEA Drosophila melanogaster 15377 R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 15377 R-DME-428690 https://reactome.org/PathwayBrowser/#/R-DME-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Drosophila melanogaster 15377 R-DME-428696 https://reactome.org/PathwayBrowser/#/R-DME-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Drosophila melanogaster 15377 R-DME-429157 https://reactome.org/PathwayBrowser/#/R-DME-429157 ABCC4 accumulation of dense granule contents IEA Drosophila melanogaster 15377 R-DME-429730 https://reactome.org/PathwayBrowser/#/R-DME-429730 PPM1L dephosphorylates multiphospho-CERT1-2 IEA Drosophila melanogaster 15377 R-DME-429860 https://reactome.org/PathwayBrowser/#/R-DME-429860 DCP1-DCP2 complex decaps mRNA IEA Drosophila melanogaster 15377 R-DME-429961 https://reactome.org/PathwayBrowser/#/R-DME-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Drosophila melanogaster 15377 R-DME-430028 https://reactome.org/PathwayBrowser/#/R-DME-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Drosophila melanogaster 15377 R-DME-432010 https://reactome.org/PathwayBrowser/#/R-DME-432010 Aquaporin-1 passively transports water into cell IEA Drosophila melanogaster 15377 R-DME-432054 https://reactome.org/PathwayBrowser/#/R-DME-432054 Aquaporin-1 passively transports water out of cell IEA Drosophila melanogaster 15377 R-DME-432065 https://reactome.org/PathwayBrowser/#/R-DME-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Drosophila melanogaster 15377 R-DME-432067 https://reactome.org/PathwayBrowser/#/R-DME-432067 Aquaporin-4 passively transports water out of cell IEA Drosophila melanogaster 15377 R-DME-4419948 https://reactome.org/PathwayBrowser/#/R-DME-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Drosophila melanogaster 15377 R-DME-449937 https://reactome.org/PathwayBrowser/#/R-DME-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Drosophila melanogaster 15377 R-DME-452036 https://reactome.org/PathwayBrowser/#/R-DME-452036 arginine + H2O => ornithine + urea [ARG2] IEA Drosophila melanogaster 15377 R-DME-4551451 https://reactome.org/PathwayBrowser/#/R-DME-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Drosophila melanogaster 15377 R-DME-504054 https://reactome.org/PathwayBrowser/#/R-DME-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Drosophila melanogaster 15377 R-DME-507868 https://reactome.org/PathwayBrowser/#/R-DME-507868 Aquaporins passively transport water into cells IEA Drosophila melanogaster 15377 R-DME-507870 https://reactome.org/PathwayBrowser/#/R-DME-507870 Aquaporins passively transport water out of cells IEA Drosophila melanogaster 15377 R-DME-508308 https://reactome.org/PathwayBrowser/#/R-DME-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Drosophila melanogaster 15377 R-DME-5221130 https://reactome.org/PathwayBrowser/#/R-DME-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Drosophila melanogaster 15377 R-DME-5251989 https://reactome.org/PathwayBrowser/#/R-DME-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Drosophila melanogaster 15377 R-DME-5362459 https://reactome.org/PathwayBrowser/#/R-DME-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Drosophila melanogaster 15377 R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster 15377 R-DME-5423647 https://reactome.org/PathwayBrowser/#/R-DME-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Drosophila melanogaster 15377 R-DME-5433072 https://reactome.org/PathwayBrowser/#/R-DME-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Drosophila melanogaster 15377 R-DME-5433074 https://reactome.org/PathwayBrowser/#/R-DME-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Drosophila melanogaster 15377 R-DME-548843 https://reactome.org/PathwayBrowser/#/R-DME-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Drosophila melanogaster 15377 R-DME-5607735 https://reactome.org/PathwayBrowser/#/R-DME-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Drosophila melanogaster 15377 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 15377 R-DME-5623513 https://reactome.org/PathwayBrowser/#/R-DME-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Drosophila melanogaster 15377 R-DME-5631885 https://reactome.org/PathwayBrowser/#/R-DME-5631885 PRDX1 overoxidizes IEA Drosophila melanogaster 15377 R-DME-5651828 https://reactome.org/PathwayBrowser/#/R-DME-5651828 PARG dePARylates PARP1,PARP2 IEA Drosophila melanogaster 15377 R-DME-5653786 https://reactome.org/PathwayBrowser/#/R-DME-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Drosophila melanogaster 15377 R-DME-5672957 https://reactome.org/PathwayBrowser/#/R-DME-5672957 PP2A dephosphorylates KSR1 IEA Drosophila melanogaster 15377 R-DME-5672961 https://reactome.org/PathwayBrowser/#/R-DME-5672961 PP2A dephosphorylates inactive RAFs IEA Drosophila melanogaster 15377 R-DME-5675376 https://reactome.org/PathwayBrowser/#/R-DME-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Drosophila melanogaster 15377 R-DME-5675431 https://reactome.org/PathwayBrowser/#/R-DME-5675431 PP2A dephosphorylates RAF1 IEA Drosophila melanogaster 15377 R-DME-5675433 https://reactome.org/PathwayBrowser/#/R-DME-5675433 PP5 dephosphorylates RAF1 S338 IEA Drosophila melanogaster 15377 R-DME-5676637 https://reactome.org/PathwayBrowser/#/R-DME-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Drosophila melanogaster 15377 R-DME-5678327 https://reactome.org/PathwayBrowser/#/R-DME-5678327 MIOX oxidises Ins to GlcA IEA Drosophila melanogaster 15377 R-DME-5678863 https://reactome.org/PathwayBrowser/#/R-DME-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-DME-5679041 https://reactome.org/PathwayBrowser/#/R-DME-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-DME-5682285 https://reactome.org/PathwayBrowser/#/R-DME-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-DME-5683714 https://reactome.org/PathwayBrowser/#/R-DME-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Drosophila melanogaster 15377 R-DME-5683967 https://reactome.org/PathwayBrowser/#/R-DME-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Drosophila melanogaster 15377 R-DME-5684864 https://reactome.org/PathwayBrowser/#/R-DME-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Drosophila melanogaster 15377 R-DME-5687464 https://reactome.org/PathwayBrowser/#/R-DME-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Drosophila melanogaster 15377 R-DME-5687664 https://reactome.org/PathwayBrowser/#/R-DME-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Drosophila melanogaster 15377 R-DME-5687758 https://reactome.org/PathwayBrowser/#/R-DME-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Drosophila melanogaster 15377 R-DME-5688797 https://reactome.org/PathwayBrowser/#/R-DME-5688797 ATXN3 family cleave Ub chains IEA Drosophila melanogaster 15377 R-DME-5689950 https://reactome.org/PathwayBrowser/#/R-DME-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Drosophila melanogaster 15377 R-DME-5689973 https://reactome.org/PathwayBrowser/#/R-DME-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Drosophila melanogaster 15377 R-DME-5690043 https://reactome.org/PathwayBrowser/#/R-DME-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 15377 R-DME-5690046 https://reactome.org/PathwayBrowser/#/R-DME-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Drosophila melanogaster 15377 R-DME-5690066 https://reactome.org/PathwayBrowser/#/R-DME-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 15377 R-DME-5690080 https://reactome.org/PathwayBrowser/#/R-DME-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Drosophila melanogaster 15377 R-DME-5690152 https://reactome.org/PathwayBrowser/#/R-DME-5690152 USP5 cleaves polyubiquitin IEA Drosophila melanogaster 15377 R-DME-5690157 https://reactome.org/PathwayBrowser/#/R-DME-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Drosophila melanogaster 15377 R-DME-5690159 https://reactome.org/PathwayBrowser/#/R-DME-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Drosophila melanogaster 15377 R-DME-5690196 https://reactome.org/PathwayBrowser/#/R-DME-5690196 USP8 deubiquitinates RNF128 IEA Drosophila melanogaster 15377 R-DME-5690319 https://reactome.org/PathwayBrowser/#/R-DME-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Drosophila melanogaster 15377 R-DME-5690517 https://reactome.org/PathwayBrowser/#/R-DME-5690517 PPT1 hydrolyses palmitoylated proteins IEA Drosophila melanogaster 15377 R-DME-5690565 https://reactome.org/PathwayBrowser/#/R-DME-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15377 R-DME-5690759 https://reactome.org/PathwayBrowser/#/R-DME-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Drosophila melanogaster 15377 R-DME-5690790 https://reactome.org/PathwayBrowser/#/R-DME-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Drosophila melanogaster 15377 R-DME-5690808 https://reactome.org/PathwayBrowser/#/R-DME-5690808 UCHL3, SENP8 cleave NEDD8 IEA Drosophila melanogaster 15377 R-DME-5690856 https://reactome.org/PathwayBrowser/#/R-DME-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Drosophila melanogaster 15377 R-DME-5690870 https://reactome.org/PathwayBrowser/#/R-DME-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Drosophila melanogaster 15377 R-DME-5691381 https://reactome.org/PathwayBrowser/#/R-DME-5691381 MYSM1 deubiquitinates Histone H2A IEA Drosophila melanogaster 15377 R-DME-5692261 https://reactome.org/PathwayBrowser/#/R-DME-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Drosophila melanogaster 15377 R-DME-5692283 https://reactome.org/PathwayBrowser/#/R-DME-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Drosophila melanogaster 15377 R-DME-5692462 https://reactome.org/PathwayBrowser/#/R-DME-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Drosophila melanogaster 15377 R-DME-5693346 https://reactome.org/PathwayBrowser/#/R-DME-5693346 CECRI deaminates Ade-Rib to Ino IEA Drosophila melanogaster 15377 R-DME-5693373 https://reactome.org/PathwayBrowser/#/R-DME-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Drosophila melanogaster 15377 R-DME-5693691 https://reactome.org/PathwayBrowser/#/R-DME-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Drosophila melanogaster 15377 R-DME-5693724 https://reactome.org/PathwayBrowser/#/R-DME-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Drosophila melanogaster 15377 R-DME-5693751 https://reactome.org/PathwayBrowser/#/R-DME-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Drosophila melanogaster 15377 R-DME-5693761 https://reactome.org/PathwayBrowser/#/R-DME-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Drosophila melanogaster 15377 R-DME-5693807 https://reactome.org/PathwayBrowser/#/R-DME-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Drosophila melanogaster 15377 R-DME-5694077 https://reactome.org/PathwayBrowser/#/R-DME-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Drosophila melanogaster 15377 R-DME-5694109 https://reactome.org/PathwayBrowser/#/R-DME-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Drosophila melanogaster 15377 R-DME-5694126 https://reactome.org/PathwayBrowser/#/R-DME-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Drosophila melanogaster 15377 R-DME-5694462 https://reactome.org/PathwayBrowser/#/R-DME-5694462 ABHD6,12 hydrolyse 3AG IEA Drosophila melanogaster 15377 R-DME-5694485 https://reactome.org/PathwayBrowser/#/R-DME-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Drosophila melanogaster 15377 R-DME-5694583 https://reactome.org/PathwayBrowser/#/R-DME-5694583 ABHD4 hydrolyses NAPE IEA Drosophila melanogaster 15377 R-DME-5696080 https://reactome.org/PathwayBrowser/#/R-DME-5696080 ALDH3B1 oxidises HXAL to PALM IEA Drosophila melanogaster 15377 R-DME-5696091 https://reactome.org/PathwayBrowser/#/R-DME-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Drosophila melanogaster 15377 R-DME-5696197 https://reactome.org/PathwayBrowser/#/R-DME-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Drosophila melanogaster 15377 R-DME-5696230 https://reactome.org/PathwayBrowser/#/R-DME-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Drosophila melanogaster 15377 R-DME-5696365 https://reactome.org/PathwayBrowser/#/R-DME-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Drosophila melanogaster 15377 R-DME-5696408 https://reactome.org/PathwayBrowser/#/R-DME-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Drosophila melanogaster 15377 R-DME-5696415 https://reactome.org/PathwayBrowser/#/R-DME-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Drosophila melanogaster 15377 R-DME-5696600 https://reactome.org/PathwayBrowser/#/R-DME-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Drosophila melanogaster 15377 R-DME-5696605 https://reactome.org/PathwayBrowser/#/R-DME-5696605 USP12, USP26 deubiquitinate AR IEA Drosophila melanogaster 15377 R-DME-5696627 https://reactome.org/PathwayBrowser/#/R-DME-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Drosophila melanogaster 15377 R-DME-5696872 https://reactome.org/PathwayBrowser/#/R-DME-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Drosophila melanogaster 15377 R-DME-5696945 https://reactome.org/PathwayBrowser/#/R-DME-5696945 USP33 deubiquitinates CCP110,ARRB IEA Drosophila melanogaster 15377 R-DME-5696968 https://reactome.org/PathwayBrowser/#/R-DME-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Drosophila melanogaster 15377 R-DME-5697009 https://reactome.org/PathwayBrowser/#/R-DME-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Drosophila melanogaster 15377 R-DME-6781764 https://reactome.org/PathwayBrowser/#/R-DME-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Drosophila melanogaster 15377 R-DME-6781779 https://reactome.org/PathwayBrowser/#/R-DME-6781779 USP13 deubiquitinates BECN1,USP10 IEA Drosophila melanogaster 15377 R-DME-6782069 https://reactome.org/PathwayBrowser/#/R-DME-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Drosophila melanogaster 15377 R-DME-6782628 https://reactome.org/PathwayBrowser/#/R-DME-6782628 USP8 deubiquitinates STAM2:HGS IEA Drosophila melanogaster 15377 R-DME-6782820 https://reactome.org/PathwayBrowser/#/R-DME-6782820 USP17 deubiquitinates SUDS3 IEA Drosophila melanogaster 15377 R-DME-6783177 https://reactome.org/PathwayBrowser/#/R-DME-6783177 USP21 deubiquitinates GATA3,IL33 IEA Drosophila melanogaster 15377 R-DME-6783221 https://reactome.org/PathwayBrowser/#/R-DME-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Drosophila melanogaster 15377 R-DME-6784959 https://reactome.org/PathwayBrowser/#/R-DME-6784959 BPHL hydrolyses VACV to ACV IEA Drosophila melanogaster 15377 R-DME-6786239 https://reactome.org/PathwayBrowser/#/R-DME-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Drosophila melanogaster 15377 R-DME-6786421 https://reactome.org/PathwayBrowser/#/R-DME-6786421 CHIA hydrolyses chitin IEA Drosophila melanogaster 15377 R-DME-6786652 https://reactome.org/PathwayBrowser/#/R-DME-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Drosophila melanogaster 15377 R-DME-6787632 https://reactome.org/PathwayBrowser/#/R-DME-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Drosophila melanogaster 15377 R-DME-6788295 https://reactome.org/PathwayBrowser/#/R-DME-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Drosophila melanogaster 15377 R-DME-6789031 https://reactome.org/PathwayBrowser/#/R-DME-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 15377 R-DME-6789126 https://reactome.org/PathwayBrowser/#/R-DME-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 15377 R-DME-6792445 https://reactome.org/PathwayBrowser/#/R-DME-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Drosophila melanogaster 15377 R-DME-6797627 https://reactome.org/PathwayBrowser/#/R-DME-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Drosophila melanogaster 15377 R-DME-6797913 https://reactome.org/PathwayBrowser/#/R-DME-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Drosophila melanogaster 15377 R-DME-6797955 https://reactome.org/PathwayBrowser/#/R-DME-6797955 ALDH7A1 oxidises BETALD to BET IEA Drosophila melanogaster 15377 R-DME-6799581 https://reactome.org/PathwayBrowser/#/R-DME-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Drosophila melanogaster 15377 R-DME-6799604 https://reactome.org/PathwayBrowser/#/R-DME-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Drosophila melanogaster 15377 R-DME-6799977 https://reactome.org/PathwayBrowser/#/R-DME-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Drosophila melanogaster 15377 R-DME-6801462 https://reactome.org/PathwayBrowser/#/R-DME-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Drosophila melanogaster 15377 R-DME-6803789 https://reactome.org/PathwayBrowser/#/R-DME-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Drosophila melanogaster 15377 R-DME-6805650 https://reactome.org/PathwayBrowser/#/R-DME-6805650 MTA2-NuRD complex deacetylates TP53 IEA Drosophila melanogaster 15377 R-DME-6807118 https://reactome.org/PathwayBrowser/#/R-DME-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Drosophila melanogaster 15377 R-DME-6807206 https://reactome.org/PathwayBrowser/#/R-DME-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Drosophila melanogaster 15377 R-DME-6808464 https://reactome.org/PathwayBrowser/#/R-DME-6808464 ALDH3B2 oxidises HXAL to PALM IEA Drosophila melanogaster 15377 R-DME-6808487 https://reactome.org/PathwayBrowser/#/R-DME-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 15377 R-DME-6808496 https://reactome.org/PathwayBrowser/#/R-DME-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 15377 R-DME-6809320 https://reactome.org/PathwayBrowser/#/R-DME-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-6809325 https://reactome.org/PathwayBrowser/#/R-DME-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Drosophila melanogaster 15377 R-DME-6809720 https://reactome.org/PathwayBrowser/#/R-DME-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Drosophila melanogaster 15377 R-DME-6809777 https://reactome.org/PathwayBrowser/#/R-DME-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Drosophila melanogaster 15377 R-DME-6809778 https://reactome.org/PathwayBrowser/#/R-DME-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Drosophila melanogaster 15377 R-DME-6810076 https://reactome.org/PathwayBrowser/#/R-DME-6810076 DDO oxidizes D-Asp to OA IEA Drosophila melanogaster 15377 R-DME-6810410 https://reactome.org/PathwayBrowser/#/R-DME-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Drosophila melanogaster 15377 R-DME-6810464 https://reactome.org/PathwayBrowser/#/R-DME-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Drosophila melanogaster 15377 R-DME-6810474 https://reactome.org/PathwayBrowser/#/R-DME-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Drosophila melanogaster 15377 R-DME-6811504 https://reactome.org/PathwayBrowser/#/R-DME-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Drosophila melanogaster 15377 R-DME-6813740 https://reactome.org/PathwayBrowser/#/R-DME-6813740 GDE1 hydrolyzes GroPIns IEA Drosophila melanogaster 15377 R-DME-6813749 https://reactome.org/PathwayBrowser/#/R-DME-6813749 ALDH1A1 oxidises GA to DGA IEA Drosophila melanogaster 15377 R-DME-6814254 https://reactome.org/PathwayBrowser/#/R-DME-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Drosophila melanogaster 15377 R-DME-69199 https://reactome.org/PathwayBrowser/#/R-DME-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Drosophila melanogaster 15377 R-DME-70262 https://reactome.org/PathwayBrowser/#/R-DME-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Drosophila melanogaster 15377 R-DME-70479 https://reactome.org/PathwayBrowser/#/R-DME-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Drosophila melanogaster 15377 R-DME-70494 https://reactome.org/PathwayBrowser/#/R-DME-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Drosophila melanogaster 15377 R-DME-70569 https://reactome.org/PathwayBrowser/#/R-DME-70569 arginine + H2O => ornithine + urea [ARG1] IEA Drosophila melanogaster 15377 R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Drosophila melanogaster 15377 R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Drosophila melanogaster 15377 R-DME-70609 https://reactome.org/PathwayBrowser/#/R-DME-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Drosophila melanogaster 15377 R-DME-70785 https://reactome.org/PathwayBrowser/#/R-DME-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Drosophila melanogaster 15377 R-DME-70870 https://reactome.org/PathwayBrowser/#/R-DME-70870 ECHS1 hydrates methacrylyl-CoA IEA Drosophila melanogaster 15377 R-DME-70881 https://reactome.org/PathwayBrowser/#/R-DME-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Drosophila melanogaster 15377 R-DME-70938 https://reactome.org/PathwayBrowser/#/R-DME-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Drosophila melanogaster 15377 R-DME-70940 https://reactome.org/PathwayBrowser/#/R-DME-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Drosophila melanogaster 15377 R-DME-70941 https://reactome.org/PathwayBrowser/#/R-DME-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Drosophila melanogaster 15377 R-DME-70975 https://reactome.org/PathwayBrowser/#/R-DME-70975 CS acetylates OA to citrate IEA Drosophila melanogaster 15377 R-DME-70982 https://reactome.org/PathwayBrowser/#/R-DME-70982 FH tetramer hydrates fumarate to L-malate IEA Drosophila melanogaster 15377 R-DME-71146 https://reactome.org/PathwayBrowser/#/R-DME-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Drosophila melanogaster 15377 R-DME-71181 https://reactome.org/PathwayBrowser/#/R-DME-71181 FAH cleaves 4FAA IEA Drosophila melanogaster 15377 R-DME-71200 https://reactome.org/PathwayBrowser/#/R-DME-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Drosophila melanogaster 15377 R-DME-71296 https://reactome.org/PathwayBrowser/#/R-DME-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Drosophila melanogaster 15377 R-DME-71660 https://reactome.org/PathwayBrowser/#/R-DME-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Drosophila melanogaster 15377 R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 15377 R-DME-71723 https://reactome.org/PathwayBrowser/#/R-DME-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Drosophila melanogaster 15377 R-DME-71732 https://reactome.org/PathwayBrowser/#/R-DME-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Drosophila melanogaster 15377 R-DME-71825 https://reactome.org/PathwayBrowser/#/R-DME-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Drosophila melanogaster 15377 R-DME-73571 https://reactome.org/PathwayBrowser/#/R-DME-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Drosophila melanogaster 15377 R-DME-73577 https://reactome.org/PathwayBrowser/#/R-DME-73577 CAD hexamer transforms L-Gln to CAP IEA Drosophila melanogaster 15377 R-DME-73589 https://reactome.org/PathwayBrowser/#/R-DME-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Drosophila melanogaster 15377 R-DME-73591 https://reactome.org/PathwayBrowser/#/R-DME-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Drosophila melanogaster 15377 R-DME-73608 https://reactome.org/PathwayBrowser/#/R-DME-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Drosophila melanogaster 15377 R-DME-73618 https://reactome.org/PathwayBrowser/#/R-DME-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Drosophila melanogaster 15377 R-DME-73620 https://reactome.org/PathwayBrowser/#/R-DME-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Drosophila melanogaster 15377 R-DME-73647 https://reactome.org/PathwayBrowser/#/R-DME-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Drosophila melanogaster 15377 R-DME-73666 https://reactome.org/PathwayBrowser/#/R-DME-73666 dUTP + H2O => dUMP + pyrophosphate IEA Drosophila melanogaster 15377 R-DME-73792 https://reactome.org/PathwayBrowser/#/R-DME-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Drosophila melanogaster 15377 R-DME-73794 https://reactome.org/PathwayBrowser/#/R-DME-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Drosophila melanogaster 15377 R-DME-73797 https://reactome.org/PathwayBrowser/#/R-DME-73797 FAICAR => IMP + H2O IEA Drosophila melanogaster 15377 R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 15377 R-DME-73815 https://reactome.org/PathwayBrowser/#/R-DME-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Drosophila melanogaster 15377 R-DME-74247 https://reactome.org/PathwayBrowser/#/R-DME-74247 XDH oxidizes hypoxanthine to form xanthine IEA Drosophila melanogaster 15377 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 15377 R-DME-74255 https://reactome.org/PathwayBrowser/#/R-DME-74255 Guanine + H2O => Xanthine + NH4+ IEA Drosophila melanogaster 15377 R-DME-74258 https://reactome.org/PathwayBrowser/#/R-DME-74258 XDH oxidizes xanthine to form urate IEA Drosophila melanogaster 15377 R-DME-74733 https://reactome.org/PathwayBrowser/#/R-DME-74733 Insulin receptor de-phosphorylation IEA Drosophila melanogaster 15377 R-DME-75872 https://reactome.org/PathwayBrowser/#/R-DME-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Drosophila melanogaster 15377 R-DME-75899 https://reactome.org/PathwayBrowser/#/R-DME-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Drosophila melanogaster 15377 R-DME-76031 https://reactome.org/PathwayBrowser/#/R-DME-76031 2 H2O2 => O2 + 2 H2O IEA Drosophila melanogaster 15377 R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 15377 R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 15377 R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 15377 R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 15377 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 15377 R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 15377 R-DME-76590 https://reactome.org/PathwayBrowser/#/R-DME-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Drosophila melanogaster 15377 R-DME-77256 https://reactome.org/PathwayBrowser/#/R-DME-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Drosophila melanogaster 15377 R-DME-77277 https://reactome.org/PathwayBrowser/#/R-DME-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Drosophila melanogaster 15377 R-DME-77301 https://reactome.org/PathwayBrowser/#/R-DME-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Drosophila melanogaster 15377 R-DME-77314 https://reactome.org/PathwayBrowser/#/R-DME-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Drosophila melanogaster 15377 R-DME-77325 https://reactome.org/PathwayBrowser/#/R-DME-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Drosophila melanogaster 15377 R-DME-77333 https://reactome.org/PathwayBrowser/#/R-DME-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Drosophila melanogaster 15377 R-DME-77344 https://reactome.org/PathwayBrowser/#/R-DME-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Drosophila melanogaster 15377 R-DME-77615 https://reactome.org/PathwayBrowser/#/R-DME-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Drosophila melanogaster 15377 R-DME-870437 https://reactome.org/PathwayBrowser/#/R-DME-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Drosophila melanogaster 15377 R-DME-8847579 https://reactome.org/PathwayBrowser/#/R-DME-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15377 R-DME-8848215 https://reactome.org/PathwayBrowser/#/R-DME-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Drosophila melanogaster 15377 R-DME-8848339 https://reactome.org/PathwayBrowser/#/R-DME-8848339 PNPLA5 hydrolyzes TAG IEA Drosophila melanogaster 15377 R-DME-8848484 https://reactome.org/PathwayBrowser/#/R-DME-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Drosophila melanogaster 15377 R-DME-8849969 https://reactome.org/PathwayBrowser/#/R-DME-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Drosophila melanogaster 15377 R-DME-8850594 https://reactome.org/PathwayBrowser/#/R-DME-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Drosophila melanogaster 15377 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 15377 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 15377 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 15377 R-DME-8853686 https://reactome.org/PathwayBrowser/#/R-DME-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Drosophila melanogaster 15377 R-DME-8854173 https://reactome.org/PathwayBrowser/#/R-DME-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Drosophila melanogaster 15377 R-DME-8854255 https://reactome.org/PathwayBrowser/#/R-DME-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 15377 R-DME-8854329 https://reactome.org/PathwayBrowser/#/R-DME-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 15377 R-DME-8854604 https://reactome.org/PathwayBrowser/#/R-DME-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Drosophila melanogaster 15377 R-DME-8855490 https://reactome.org/PathwayBrowser/#/R-DME-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Drosophila melanogaster 15377 R-DME-8856951 https://reactome.org/PathwayBrowser/#/R-DME-8856951 PP2A demethylation by PPME1 IEA Drosophila melanogaster 15377 R-DME-8862320 https://reactome.org/PathwayBrowser/#/R-DME-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Drosophila melanogaster 15377 R-DME-8864125 https://reactome.org/PathwayBrowser/#/R-DME-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Drosophila melanogaster 15377 R-DME-8866601 https://reactome.org/PathwayBrowser/#/R-DME-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Drosophila melanogaster 15377 R-DME-8867047 https://reactome.org/PathwayBrowser/#/R-DME-8867047 PTPN3 dephosphorylates EPS15 IEA Drosophila melanogaster 15377 R-DME-8867658 https://reactome.org/PathwayBrowser/#/R-DME-8867658 PTPN3 dephosphorylates MAPK12 IEA Drosophila melanogaster 15377 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster 15377 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster 15377 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster 15377 R-DME-8869425 https://reactome.org/PathwayBrowser/#/R-DME-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Drosophila melanogaster 15377 R-DME-8869506 https://reactome.org/PathwayBrowser/#/R-DME-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Drosophila melanogaster 15377 R-DME-8874435 https://reactome.org/PathwayBrowser/#/R-DME-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Drosophila melanogaster 15377 R-DME-8878787 https://reactome.org/PathwayBrowser/#/R-DME-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Drosophila melanogaster 15377 R-DME-888548 https://reactome.org/PathwayBrowser/#/R-DME-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Drosophila melanogaster 15377 R-DME-8933635 https://reactome.org/PathwayBrowser/#/R-DME-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Drosophila melanogaster 15377 R-DME-8936442 https://reactome.org/PathwayBrowser/#/R-DME-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Drosophila melanogaster 15377 R-DME-8937442 https://reactome.org/PathwayBrowser/#/R-DME-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Drosophila melanogaster 15377 R-DME-8940070 https://reactome.org/PathwayBrowser/#/R-DME-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Drosophila melanogaster 15377 R-DME-8940074 https://reactome.org/PathwayBrowser/#/R-DME-8940074 NT5E:Zn2+ hydrolyses NMN IEA Drosophila melanogaster 15377 R-DME-8943279 https://reactome.org/PathwayBrowser/#/R-DME-8943279 GGT dimers hydrolyse GSH IEA Drosophila melanogaster 15377 R-DME-8952069 https://reactome.org/PathwayBrowser/#/R-DME-8952069 HDAC4 deacetylates RUNX3 IEA Drosophila melanogaster 15377 R-DME-8952137 https://reactome.org/PathwayBrowser/#/R-DME-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Drosophila melanogaster 15377 R-DME-8952251 https://reactome.org/PathwayBrowser/#/R-DME-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Drosophila melanogaster 15377 R-DME-8953499 https://reactome.org/PathwayBrowser/#/R-DME-8953499 IMPAD1 hydrolyses PAP to AMP IEA Drosophila melanogaster 15377 R-DME-8954398 https://reactome.org/PathwayBrowser/#/R-DME-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Drosophila melanogaster 15377 R-DME-8955817 https://reactome.org/PathwayBrowser/#/R-DME-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Drosophila melanogaster 15377 R-DME-8957389 https://reactome.org/PathwayBrowser/#/R-DME-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Drosophila melanogaster 15377 R-DME-8959510 https://reactome.org/PathwayBrowser/#/R-DME-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Drosophila melanogaster 15377 R-DME-8980228 https://reactome.org/PathwayBrowser/#/R-DME-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Drosophila melanogaster 15377 R-DME-8981637 https://reactome.org/PathwayBrowser/#/R-DME-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Drosophila melanogaster 15377 R-DME-8986083 https://reactome.org/PathwayBrowser/#/R-DME-8986083 USP33 deubiquitinates ROBO1 IEA Drosophila melanogaster 15377 R-DME-9008822 https://reactome.org/PathwayBrowser/#/R-DME-9008822 PPM1D dephosphorylates RUNX2 IEA Drosophila melanogaster 15377 R-DME-9009950 https://reactome.org/PathwayBrowser/#/R-DME-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Drosophila melanogaster 15377 R-DME-9013022 https://reactome.org/PathwayBrowser/#/R-DME-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Drosophila melanogaster 15377 R-DME-9013144 https://reactome.org/PathwayBrowser/#/R-DME-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Drosophila melanogaster 15377 R-DME-9013161 https://reactome.org/PathwayBrowser/#/R-DME-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Drosophila melanogaster 15377 R-DME-9013437 https://reactome.org/PathwayBrowser/#/R-DME-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Drosophila melanogaster 15377 R-DME-9014295 https://reactome.org/PathwayBrowser/#/R-DME-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Drosophila melanogaster 15377 R-DME-9014434 https://reactome.org/PathwayBrowser/#/R-DME-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Drosophila melanogaster 15377 R-DME-9017488 https://reactome.org/PathwayBrowser/#/R-DME-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Drosophila melanogaster 15377 R-DME-9018745 https://reactome.org/PathwayBrowser/#/R-DME-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Drosophila melanogaster 15377 R-DME-9018806 https://reactome.org/PathwayBrowser/#/R-DME-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Drosophila melanogaster 15377 R-DME-9018814 https://reactome.org/PathwayBrowser/#/R-DME-9018814 RHOT1 hydrolyzes GTP IEA Drosophila melanogaster 15377 R-DME-9018826 https://reactome.org/PathwayBrowser/#/R-DME-9018826 RHOT2 hydrolyzes GTP IEA Drosophila melanogaster 15377 R-DME-9018862 https://reactome.org/PathwayBrowser/#/R-DME-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Drosophila melanogaster 15377 R-DME-9018877 https://reactome.org/PathwayBrowser/#/R-DME-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Drosophila melanogaster 15377 R-DME-9020252 https://reactome.org/PathwayBrowser/#/R-DME-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Drosophila melanogaster 15377 R-DME-9020253 https://reactome.org/PathwayBrowser/#/R-DME-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Drosophila melanogaster 15377 R-DME-9020257 https://reactome.org/PathwayBrowser/#/R-DME-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Drosophila melanogaster 15377 R-DME-9020258 https://reactome.org/PathwayBrowser/#/R-DME-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Drosophila melanogaster 15377 R-DME-9020270 https://reactome.org/PathwayBrowser/#/R-DME-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Drosophila melanogaster 15377 R-DME-9024890 https://reactome.org/PathwayBrowser/#/R-DME-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Drosophila melanogaster 15377 R-DME-9027043 https://reactome.org/PathwayBrowser/#/R-DME-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Drosophila melanogaster 15377 R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 15377 R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 15377 R-DME-9033491 https://reactome.org/PathwayBrowser/#/R-DME-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Drosophila melanogaster 15377 R-DME-9033520 https://reactome.org/PathwayBrowser/#/R-DME-9033520 TYSND1 cleaves TYSND1 IEA Drosophila melanogaster 15377 R-DME-917841 https://reactome.org/PathwayBrowser/#/R-DME-917841 Acidification of Tf:TfR1 containing endosome IEA Drosophila melanogaster 15377 R-DME-917979 https://reactome.org/PathwayBrowser/#/R-DME-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-DME-936883 https://reactome.org/PathwayBrowser/#/R-DME-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Drosophila melanogaster 15377 R-DME-936895 https://reactome.org/PathwayBrowser/#/R-DME-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Drosophila melanogaster 15377 R-DME-939763 https://reactome.org/PathwayBrowser/#/R-DME-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Drosophila melanogaster 15377 R-DME-947531 https://reactome.org/PathwayBrowser/#/R-DME-947531 Molybdenum ion transfer onto molybdopterin IEA Drosophila melanogaster 15377 R-DME-947535 https://reactome.org/PathwayBrowser/#/R-DME-947535 Cyclisation of GTP to precursor Z IEA Drosophila melanogaster 15377 R-DME-947591 https://reactome.org/PathwayBrowser/#/R-DME-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Drosophila melanogaster 15377 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 15377 R-DME-9620103 https://reactome.org/PathwayBrowser/#/R-DME-9620103 ALDH2 transforms GTN to NO IEA Drosophila melanogaster 15377 R-DME-9624893 https://reactome.org/PathwayBrowser/#/R-DME-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Drosophila melanogaster 15377 R-DME-9635739 https://reactome.org/PathwayBrowser/#/R-DME-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Drosophila melanogaster 15377 R-DME-9638075 https://reactome.org/PathwayBrowser/#/R-DME-9638075 HEXB cleaves the terminal GalNAc from DS IEA Drosophila melanogaster 15377 R-DME-9638076 https://reactome.org/PathwayBrowser/#/R-DME-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Drosophila melanogaster 15377 R-DME-9638078 https://reactome.org/PathwayBrowser/#/R-DME-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Drosophila melanogaster 15377 R-DME-9644869 https://reactome.org/PathwayBrowser/#/R-DME-9644869 p-S54-PDE4B hydrolyses cAMP IEA Drosophila melanogaster 15377 R-DME-9647994 https://reactome.org/PathwayBrowser/#/R-DME-9647994 RAS proteins are depalmitoylated IEA Drosophila melanogaster 15377 R-DME-965079 https://reactome.org/PathwayBrowser/#/R-DME-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Drosophila melanogaster 15377 R-DME-9653514 https://reactome.org/PathwayBrowser/#/R-DME-9653514 USP17L2 deubiquitinates RCE1 IEA Drosophila melanogaster 15377 R-DME-9661417 https://reactome.org/PathwayBrowser/#/R-DME-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-DME-9667952 https://reactome.org/PathwayBrowser/#/R-DME-9667952 ANKLE2 is deacetylated by SIRT2 IEA Drosophila melanogaster 15377 R-DME-9674127 https://reactome.org/PathwayBrowser/#/R-DME-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Drosophila melanogaster 15377 R-DME-9693282 https://reactome.org/PathwayBrowser/#/R-DME-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Drosophila melanogaster 15377 R-DME-9701565 https://reactome.org/PathwayBrowser/#/R-DME-9701565 HDACs deacetylate p-STAT3 dimers IEA Drosophila melanogaster 15377 R-DME-9706399 https://reactome.org/PathwayBrowser/#/R-DME-9706399 RHOBTB3 hydrolyzes ATP IEA Drosophila melanogaster 15377 R-DME-9708261 https://reactome.org/PathwayBrowser/#/R-DME-9708261 PDE4A hydrolyses cAMP to AMP IEA Drosophila melanogaster 15377 R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 15377 R-DME-9727349 https://reactome.org/PathwayBrowser/#/R-DME-9727349 XDH dehydrogenates xanthine to form urate IEA Drosophila melanogaster 15377 R-DME-9727567 https://reactome.org/PathwayBrowser/#/R-DME-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Drosophila melanogaster 15377 R-DME-9731661 https://reactome.org/PathwayBrowser/#/R-DME-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Drosophila melanogaster 15377 R-DME-9748945 https://reactome.org/PathwayBrowser/#/R-DME-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Drosophila melanogaster 15377 R-DME-9748957 https://reactome.org/PathwayBrowser/#/R-DME-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Drosophila melanogaster 15377 R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 15377 R-DME-9749609 https://reactome.org/PathwayBrowser/#/R-DME-9749609 BCHE hydrolyzes ASA- IEA Drosophila melanogaster 15377 R-DME-9749647 https://reactome.org/PathwayBrowser/#/R-DME-9749647 CES2 hydrolyzes ASA- IEA Drosophila melanogaster 15377 R-DME-9749792 https://reactome.org/PathwayBrowser/#/R-DME-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Drosophila melanogaster 15377 R-DME-9749986 https://reactome.org/PathwayBrowser/#/R-DME-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Drosophila melanogaster 15377 R-DME-9750016 https://reactome.org/PathwayBrowser/#/R-DME-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Drosophila melanogaster 15377 R-DME-9750546 https://reactome.org/PathwayBrowser/#/R-DME-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-DME-9750656 https://reactome.org/PathwayBrowser/#/R-DME-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Drosophila melanogaster 15377 R-DME-9753278 https://reactome.org/PathwayBrowser/#/R-DME-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 15377 R-DME-9753280 https://reactome.org/PathwayBrowser/#/R-DME-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Drosophila melanogaster 15377 R-DME-9753283 https://reactome.org/PathwayBrowser/#/R-DME-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 15377 R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-DME-9753285 https://reactome.org/PathwayBrowser/#/R-DME-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Drosophila melanogaster 15377 R-DME-9753632 https://reactome.org/PathwayBrowser/#/R-DME-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Drosophila melanogaster 15377 R-DME-9753634 https://reactome.org/PathwayBrowser/#/R-DME-9753634 GGT dimers hydrolyse APAP-SG IEA Drosophila melanogaster 15377 R-DME-9753944 https://reactome.org/PathwayBrowser/#/R-DME-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Drosophila melanogaster 15377 R-DME-9755030 https://reactome.org/PathwayBrowser/#/R-DME-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Drosophila melanogaster 15377 R-DME-9755078 https://reactome.org/PathwayBrowser/#/R-DME-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Drosophila melanogaster 15377 R-DME-975594 https://reactome.org/PathwayBrowser/#/R-DME-975594 PLB1 hydrolyses RPALM to atROL IEA Drosophila melanogaster 15377 R-DME-977324 https://reactome.org/PathwayBrowser/#/R-DME-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Drosophila melanogaster 15377 R-DME-9794120 https://reactome.org/PathwayBrowser/#/R-DME-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Drosophila melanogaster 15377 R-DME-9794572 https://reactome.org/PathwayBrowser/#/R-DME-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Drosophila melanogaster 15377 R-DME-9838004 https://reactome.org/PathwayBrowser/#/R-DME-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Drosophila melanogaster 15377 R-DME-9838081 https://reactome.org/PathwayBrowser/#/R-DME-9838081 LONP1 degrades mitochondrial matrix proteins IEA Drosophila melanogaster 15377 R-DME-9838289 https://reactome.org/PathwayBrowser/#/R-DME-9838289 CLPXP degrades mitochondrial matrix proteins IEA Drosophila melanogaster 15377 R-DME-9839059 https://reactome.org/PathwayBrowser/#/R-DME-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Drosophila melanogaster 15377 R-DME-9839072 https://reactome.org/PathwayBrowser/#/R-DME-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Drosophila melanogaster 15377 R-DME-9839105 https://reactome.org/PathwayBrowser/#/R-DME-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Drosophila melanogaster 15377 R-DME-9839110 https://reactome.org/PathwayBrowser/#/R-DME-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Drosophila melanogaster 15377 R-DME-9839113 https://reactome.org/PathwayBrowser/#/R-DME-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Drosophila melanogaster 15377 R-DME-9843721 https://reactome.org/PathwayBrowser/#/R-DME-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Drosophila melanogaster 15377 R-DME-9853385 https://reactome.org/PathwayBrowser/#/R-DME-9853385 PPP1CC dephosphorylates PLK1 IEA Drosophila melanogaster 15377 R-DME-9861626 https://reactome.org/PathwayBrowser/#/R-DME-9861626 SIRT4 cleaves lipoyl from DLAT IEA Drosophila melanogaster 15377 R-DME-9861725 https://reactome.org/PathwayBrowser/#/R-DME-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Drosophila melanogaster 15377 R-DME-997326 https://reactome.org/PathwayBrowser/#/R-DME-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Drosophila melanogaster 15377 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 15377 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 15377 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 15377 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 15377 R-DRE-109415 https://reactome.org/PathwayBrowser/#/R-DRE-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Danio rerio 15377 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 15377 R-DRE-111742 https://reactome.org/PathwayBrowser/#/R-DRE-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 15377 R-DRE-111751 https://reactome.org/PathwayBrowser/#/R-DRE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 15377 R-DRE-111804 https://reactome.org/PathwayBrowser/#/R-DRE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 15377 R-DRE-111883 https://reactome.org/PathwayBrowser/#/R-DRE-111883 Hydrolysis of phosphatidylcholine IEA Danio rerio 15377 R-DRE-113503 https://reactome.org/PathwayBrowser/#/R-DRE-113503 PP2A mediated localization of RB1 protein in chromatin IEA Danio rerio 15377 R-DRE-1169192 https://reactome.org/PathwayBrowser/#/R-DRE-1169192 PTP1B dephosphorylates GHR IEA Danio rerio 15377 R-DRE-1237047 https://reactome.org/PathwayBrowser/#/R-DRE-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Danio rerio 15377 R-DRE-1237059 https://reactome.org/PathwayBrowser/#/R-DRE-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Danio rerio 15377 R-DRE-1237129 https://reactome.org/PathwayBrowser/#/R-DRE-1237129 Acireductone is created IEA Danio rerio 15377 R-DRE-1247910 https://reactome.org/PathwayBrowser/#/R-DRE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Danio rerio 15377 R-DRE-1247935 https://reactome.org/PathwayBrowser/#/R-DRE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Danio rerio 15377 R-DRE-1363274 https://reactome.org/PathwayBrowser/#/R-DRE-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Danio rerio 15377 R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 15377 R-DRE-140359 https://reactome.org/PathwayBrowser/#/R-DRE-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Danio rerio 15377 R-DRE-141200 https://reactome.org/PathwayBrowser/#/R-DRE-141200 MAOB:FAD oxidatively deaminates of PEA IEA Danio rerio 15377 R-DRE-141202 https://reactome.org/PathwayBrowser/#/R-DRE-141202 MAOB:FAD oxidatively deaminates TYR IEA Danio rerio 15377 R-DRE-141348 https://reactome.org/PathwayBrowser/#/R-DRE-141348 PAO:FAD oxidises NASPM to PTCN IEA Danio rerio 15377 R-DRE-141351 https://reactome.org/PathwayBrowser/#/R-DRE-141351 PAOX:FAD oxidises NASPN to SPM IEA Danio rerio 15377 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 15377 R-DRE-1454916 https://reactome.org/PathwayBrowser/#/R-DRE-1454916 The ABCC family mediates organic anion transport IEA Danio rerio 15377 R-DRE-1454928 https://reactome.org/PathwayBrowser/#/R-DRE-1454928 ABCG4 may mediate cholesterol efflux IEA Danio rerio 15377 R-DRE-1475017 https://reactome.org/PathwayBrowser/#/R-DRE-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Danio rerio 15377 R-DRE-1475022 https://reactome.org/PathwayBrowser/#/R-DRE-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Danio rerio 15377 R-DRE-1475025 https://reactome.org/PathwayBrowser/#/R-DRE-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Danio rerio 15377 R-DRE-1475026 https://reactome.org/PathwayBrowser/#/R-DRE-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Danio rerio 15377 R-DRE-1475028 https://reactome.org/PathwayBrowser/#/R-DRE-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Danio rerio 15377 R-DRE-1475032 https://reactome.org/PathwayBrowser/#/R-DRE-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Danio rerio 15377 R-DRE-1475435 https://reactome.org/PathwayBrowser/#/R-DRE-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Danio rerio 15377 R-DRE-1475436 https://reactome.org/PathwayBrowser/#/R-DRE-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Danio rerio 15377 R-DRE-1482543 https://reactome.org/PathwayBrowser/#/R-DRE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Danio rerio 15377 R-DRE-1482545 https://reactome.org/PathwayBrowser/#/R-DRE-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Danio rerio 15377 R-DRE-1482571 https://reactome.org/PathwayBrowser/#/R-DRE-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Danio rerio 15377 R-DRE-1482604 https://reactome.org/PathwayBrowser/#/R-DRE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Danio rerio 15377 R-DRE-1482612 https://reactome.org/PathwayBrowser/#/R-DRE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 15377 R-DRE-1482629 https://reactome.org/PathwayBrowser/#/R-DRE-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Danio rerio 15377 R-DRE-1482656 https://reactome.org/PathwayBrowser/#/R-DRE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Danio rerio 15377 R-DRE-1482685 https://reactome.org/PathwayBrowser/#/R-DRE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 15377 R-DRE-1482696 https://reactome.org/PathwayBrowser/#/R-DRE-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Danio rerio 15377 R-DRE-1482759 https://reactome.org/PathwayBrowser/#/R-DRE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Danio rerio 15377 R-DRE-1482771 https://reactome.org/PathwayBrowser/#/R-DRE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Danio rerio 15377 R-DRE-1482777 https://reactome.org/PathwayBrowser/#/R-DRE-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Danio rerio 15377 R-DRE-1482811 https://reactome.org/PathwayBrowser/#/R-DRE-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Danio rerio 15377 R-DRE-1482816 https://reactome.org/PathwayBrowser/#/R-DRE-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Danio rerio 15377 R-DRE-1482825 https://reactome.org/PathwayBrowser/#/R-DRE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Danio rerio 15377 R-DRE-1482827 https://reactome.org/PathwayBrowser/#/R-DRE-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Danio rerio 15377 R-DRE-1482828 https://reactome.org/PathwayBrowser/#/R-DRE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Danio rerio 15377 R-DRE-1482856 https://reactome.org/PathwayBrowser/#/R-DRE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Danio rerio 15377 R-DRE-1482862 https://reactome.org/PathwayBrowser/#/R-DRE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Danio rerio 15377 R-DRE-1482868 https://reactome.org/PathwayBrowser/#/R-DRE-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Danio rerio 15377 R-DRE-1482884 https://reactome.org/PathwayBrowser/#/R-DRE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Danio rerio 15377 R-DRE-1482892 https://reactome.org/PathwayBrowser/#/R-DRE-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Danio rerio 15377 R-DRE-1482897 https://reactome.org/PathwayBrowser/#/R-DRE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Danio rerio 15377 R-DRE-1482900 https://reactome.org/PathwayBrowser/#/R-DRE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Danio rerio 15377 R-DRE-1483096 https://reactome.org/PathwayBrowser/#/R-DRE-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Danio rerio 15377 R-DRE-1483159 https://reactome.org/PathwayBrowser/#/R-DRE-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Danio rerio 15377 R-DRE-1483203 https://reactome.org/PathwayBrowser/#/R-DRE-1483203 PA is dephosphorylated to DAG by LPIN IEA Danio rerio 15377 R-DRE-156526 https://reactome.org/PathwayBrowser/#/R-DRE-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Danio rerio 15377 R-DRE-159425 https://reactome.org/PathwayBrowser/#/R-DRE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 15377 R-DRE-1602368 https://reactome.org/PathwayBrowser/#/R-DRE-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Danio rerio 15377 R-DRE-1602374 https://reactome.org/PathwayBrowser/#/R-DRE-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Danio rerio 15377 R-DRE-1602377 https://reactome.org/PathwayBrowser/#/R-DRE-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Danio rerio 15377 R-DRE-1602398 https://reactome.org/PathwayBrowser/#/R-DRE-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Danio rerio 15377 R-DRE-1602417 https://reactome.org/PathwayBrowser/#/R-DRE-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Danio rerio 15377 R-DRE-1602446 https://reactome.org/PathwayBrowser/#/R-DRE-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Danio rerio 15377 R-DRE-1605723 https://reactome.org/PathwayBrowser/#/R-DRE-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Danio rerio 15377 R-DRE-1605768 https://reactome.org/PathwayBrowser/#/R-DRE-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Danio rerio 15377 R-DRE-1606273 https://reactome.org/PathwayBrowser/#/R-DRE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Danio rerio 15377 R-DRE-1606288 https://reactome.org/PathwayBrowser/#/R-DRE-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Danio rerio 15377 R-DRE-1606583 https://reactome.org/PathwayBrowser/#/R-DRE-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Danio rerio 15377 R-DRE-1614524 https://reactome.org/PathwayBrowser/#/R-DRE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Danio rerio 15377 R-DRE-1614583 https://reactome.org/PathwayBrowser/#/R-DRE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Danio rerio 15377 R-DRE-1614605 https://reactome.org/PathwayBrowser/#/R-DRE-1614605 Persulfide sulfur is dioxygenated IEA Danio rerio 15377 R-DRE-1614614 https://reactome.org/PathwayBrowser/#/R-DRE-1614614 Cysteine is degraded to serine and H2S IEA Danio rerio 15377 R-DRE-1614631 https://reactome.org/PathwayBrowser/#/R-DRE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Danio rerio 15377 R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 15377 R-DRE-1638032 https://reactome.org/PathwayBrowser/#/R-DRE-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Danio rerio 15377 R-DRE-164832 https://reactome.org/PathwayBrowser/#/R-DRE-164832 ATPase synthesizes ATP IEA Danio rerio 15377 R-DRE-1655453 https://reactome.org/PathwayBrowser/#/R-DRE-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Danio rerio 15377 R-DRE-1667005 https://reactome.org/PathwayBrowser/#/R-DRE-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Danio rerio 15377 R-DRE-1675795 https://reactome.org/PathwayBrowser/#/R-DRE-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Danio rerio 15377 R-DRE-1675949 https://reactome.org/PathwayBrowser/#/R-DRE-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Danio rerio 15377 R-DRE-1675994 https://reactome.org/PathwayBrowser/#/R-DRE-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Danio rerio 15377 R-DRE-1676065 https://reactome.org/PathwayBrowser/#/R-DRE-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Danio rerio 15377 R-DRE-1676105 https://reactome.org/PathwayBrowser/#/R-DRE-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Danio rerio 15377 R-DRE-1676114 https://reactome.org/PathwayBrowser/#/R-DRE-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Danio rerio 15377 R-DRE-1676124 https://reactome.org/PathwayBrowser/#/R-DRE-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Danio rerio 15377 R-DRE-1676141 https://reactome.org/PathwayBrowser/#/R-DRE-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Danio rerio 15377 R-DRE-1676149 https://reactome.org/PathwayBrowser/#/R-DRE-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Danio rerio 15377 R-DRE-1676162 https://reactome.org/PathwayBrowser/#/R-DRE-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Danio rerio 15377 R-DRE-1676164 https://reactome.org/PathwayBrowser/#/R-DRE-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Danio rerio 15377 R-DRE-1676203 https://reactome.org/PathwayBrowser/#/R-DRE-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Danio rerio 15377 R-DRE-1676204 https://reactome.org/PathwayBrowser/#/R-DRE-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Danio rerio 15377 R-DRE-1678650 https://reactome.org/PathwayBrowser/#/R-DRE-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Danio rerio 15377 R-DRE-173597 https://reactome.org/PathwayBrowser/#/R-DRE-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Danio rerio 15377 R-DRE-173739 https://reactome.org/PathwayBrowser/#/R-DRE-173739 Spontaneous hydrolysis of C3 thioester IEA Danio rerio 15377 R-DRE-174124 https://reactome.org/PathwayBrowser/#/R-DRE-174124 Dephosphorylation of phospho-Cdh1 IEA Danio rerio 15377 R-DRE-174391 https://reactome.org/PathwayBrowser/#/R-DRE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Danio rerio 15377 R-DRE-174401 https://reactome.org/PathwayBrowser/#/R-DRE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Danio rerio 15377 R-DRE-1793182 https://reactome.org/PathwayBrowser/#/R-DRE-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Danio rerio 15377 R-DRE-1793209 https://reactome.org/PathwayBrowser/#/R-DRE-1793209 HYAL1 hydrolyses Chondroitin chains IEA Danio rerio 15377 R-DRE-1855154 https://reactome.org/PathwayBrowser/#/R-DRE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 15377 R-DRE-1855159 https://reactome.org/PathwayBrowser/#/R-DRE-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Danio rerio 15377 R-DRE-1855163 https://reactome.org/PathwayBrowser/#/R-DRE-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Danio rerio 15377 R-DRE-1855165 https://reactome.org/PathwayBrowser/#/R-DRE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 15377 R-DRE-1855166 https://reactome.org/PathwayBrowser/#/R-DRE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Danio rerio 15377 R-DRE-1855171 https://reactome.org/PathwayBrowser/#/R-DRE-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Danio rerio 15377 R-DRE-1855180 https://reactome.org/PathwayBrowser/#/R-DRE-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Danio rerio 15377 R-DRE-1855198 https://reactome.org/PathwayBrowser/#/R-DRE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 15377 R-DRE-1855200 https://reactome.org/PathwayBrowser/#/R-DRE-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Danio rerio 15377 R-DRE-1855202 https://reactome.org/PathwayBrowser/#/R-DRE-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Danio rerio 15377 R-DRE-1855205 https://reactome.org/PathwayBrowser/#/R-DRE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Danio rerio 15377 R-DRE-1855210 https://reactome.org/PathwayBrowser/#/R-DRE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 15377 R-DRE-1855211 https://reactome.org/PathwayBrowser/#/R-DRE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 15377 R-DRE-1855218 https://reactome.org/PathwayBrowser/#/R-DRE-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Danio rerio 15377 R-DRE-1855219 https://reactome.org/PathwayBrowser/#/R-DRE-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Danio rerio 15377 R-DRE-1855221 https://reactome.org/PathwayBrowser/#/R-DRE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Danio rerio 15377 R-DRE-1855222 https://reactome.org/PathwayBrowser/#/R-DRE-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Danio rerio 15377 R-DRE-1855225 https://reactome.org/PathwayBrowser/#/R-DRE-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Danio rerio 15377 R-DRE-1861788 https://reactome.org/PathwayBrowser/#/R-DRE-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Danio rerio 15377 R-DRE-1861789 https://reactome.org/PathwayBrowser/#/R-DRE-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Danio rerio 15377 R-DRE-188979 https://reactome.org/PathwayBrowser/#/R-DRE-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Danio rerio 15377 R-DRE-189398 https://reactome.org/PathwayBrowser/#/R-DRE-189398 HMOX1 dimer, HMOX2 cleave heme IEA Danio rerio 15377 R-DRE-189421 https://reactome.org/PathwayBrowser/#/R-DRE-189421 CPO transforms COPRO3 to PPGEN9 IEA Danio rerio 15377 R-DRE-189439 https://reactome.org/PathwayBrowser/#/R-DRE-189439 ALAD condenses 2 dALAs to form PBG IEA Danio rerio 15377 R-DRE-189488 https://reactome.org/PathwayBrowser/#/R-DRE-189488 UROS transforms HMB to URO3 IEA Danio rerio 15377 R-DRE-191114 https://reactome.org/PathwayBrowser/#/R-DRE-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Danio rerio 15377 R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 15377 R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 15377 R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 15377 R-DRE-192157 https://reactome.org/PathwayBrowser/#/R-DRE-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Danio rerio 15377 R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 15377 R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 15377 R-DRE-192430 https://reactome.org/PathwayBrowser/#/R-DRE-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 15377 R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 15377 R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 15377 R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 15377 R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 15377 R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 15377 R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 15377 R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 15377 R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 15377 R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 15377 R-DRE-193385 https://reactome.org/PathwayBrowser/#/R-DRE-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Danio rerio 15377 R-DRE-193709 https://reactome.org/PathwayBrowser/#/R-DRE-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Danio rerio 15377 R-DRE-193711 https://reactome.org/PathwayBrowser/#/R-DRE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 15377 R-DRE-193766 https://reactome.org/PathwayBrowser/#/R-DRE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 15377 R-DRE-193845 https://reactome.org/PathwayBrowser/#/R-DRE-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Danio rerio 15377 R-DRE-194641 https://reactome.org/PathwayBrowser/#/R-DRE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15377 R-DRE-194669 https://reactome.org/PathwayBrowser/#/R-DRE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15377 R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 15377 R-DRE-195664 https://reactome.org/PathwayBrowser/#/R-DRE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Danio rerio 15377 R-DRE-196950 https://reactome.org/PathwayBrowser/#/R-DRE-196950 2xTRAP hydrolyzes FMN to RIB IEA Danio rerio 15377 R-DRE-196955 https://reactome.org/PathwayBrowser/#/R-DRE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Danio rerio 15377 R-DRE-197271 https://reactome.org/PathwayBrowser/#/R-DRE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Danio rerio 15377 R-DRE-199456 https://reactome.org/PathwayBrowser/#/R-DRE-199456 PTEN dephosphorylates PIP3 IEA Danio rerio 15377 R-DRE-199959 https://reactome.org/PathwayBrowser/#/R-DRE-199959 ERKs are inactivated by protein phosphatase 2A IEA Danio rerio 15377 R-DRE-2002466 https://reactome.org/PathwayBrowser/#/R-DRE-2002466 Formation of allysine by LOX IEA Danio rerio 15377 R-DRE-200661 https://reactome.org/PathwayBrowser/#/R-DRE-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio 15377 R-DRE-200740 https://reactome.org/PathwayBrowser/#/R-DRE-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Danio rerio 15377 R-DRE-201035 https://reactome.org/PathwayBrowser/#/R-DRE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Danio rerio 15377 R-DRE-2022381 https://reactome.org/PathwayBrowser/#/R-DRE-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Danio rerio 15377 R-DRE-2022412 https://reactome.org/PathwayBrowser/#/R-DRE-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Danio rerio 15377 R-DRE-2022887 https://reactome.org/PathwayBrowser/#/R-DRE-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Danio rerio 15377 R-DRE-2023971 https://reactome.org/PathwayBrowser/#/R-DRE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 15377 R-DRE-2023973 https://reactome.org/PathwayBrowser/#/R-DRE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 15377 R-DRE-202407 https://reactome.org/PathwayBrowser/#/R-DRE-202407 PLC-gamma1 hydrolyses PIP2 IEA Danio rerio 15377 R-DRE-2028294 https://reactome.org/PathwayBrowser/#/R-DRE-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Danio rerio 15377 R-DRE-203797 https://reactome.org/PathwayBrowser/#/R-DRE-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Danio rerio 15377 R-DRE-2046083 https://reactome.org/PathwayBrowser/#/R-DRE-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Danio rerio 15377 R-DRE-2046084 https://reactome.org/PathwayBrowser/#/R-DRE-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Danio rerio 15377 R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio 15377 R-DRE-2046090 https://reactome.org/PathwayBrowser/#/R-DRE-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 15377 R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio 15377 R-DRE-2046095 https://reactome.org/PathwayBrowser/#/R-DRE-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Danio rerio 15377 R-DRE-2046096 https://reactome.org/PathwayBrowser/#/R-DRE-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Danio rerio 15377 R-DRE-2046097 https://reactome.org/PathwayBrowser/#/R-DRE-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 15377 R-DRE-2046100 https://reactome.org/PathwayBrowser/#/R-DRE-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Danio rerio 15377 R-DRE-204662 https://reactome.org/PathwayBrowser/#/R-DRE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Danio rerio 15377 R-DRE-2066779 https://reactome.org/PathwayBrowser/#/R-DRE-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Danio rerio 15377 R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 15377 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 15377 R-DRE-209891 https://reactome.org/PathwayBrowser/#/R-DRE-209891 Dopamine is oxidised to noradrenaline IEA Danio rerio 15377 R-DRE-211873 https://reactome.org/PathwayBrowser/#/R-DRE-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Danio rerio 15377 R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 15377 R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 15377 R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 15377 R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 15377 R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 15377 R-DRE-211923 https://reactome.org/PathwayBrowser/#/R-DRE-211923 CYP26C1 4-hydroxylates 9cRA IEA Danio rerio 15377 R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 15377 R-DRE-211950 https://reactome.org/PathwayBrowser/#/R-DRE-211950 CYP24A1 24-hydroxylates CTL IEA Danio rerio 15377 R-DRE-211951 https://reactome.org/PathwayBrowser/#/R-DRE-211951 CYP1B1 4-hydroxylates EST17b IEA Danio rerio 15377 R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 15377 R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 15377 R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 15377 R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 15377 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 15377 R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 15377 R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 15377 R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 15377 R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 15377 R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 15377 R-DRE-2160874 https://reactome.org/PathwayBrowser/#/R-DRE-2160874 HYAL1 hydrolyses (HA)50 IEA Danio rerio 15377 R-DRE-2161187 https://reactome.org/PathwayBrowser/#/R-DRE-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Danio rerio 15377 R-DRE-2161195 https://reactome.org/PathwayBrowser/#/R-DRE-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Danio rerio 15377 R-DRE-2161745 https://reactome.org/PathwayBrowser/#/R-DRE-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Danio rerio 15377 R-DRE-2161792 https://reactome.org/PathwayBrowser/#/R-DRE-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Danio rerio 15377 R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Danio rerio 15377 R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 15377 R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio 15377 R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Danio rerio 15377 R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 15377 R-DRE-2161951 https://reactome.org/PathwayBrowser/#/R-DRE-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Danio rerio 15377 R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Danio rerio 15377 R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 15377 R-DRE-216723 https://reactome.org/PathwayBrowser/#/R-DRE-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Danio rerio 15377 R-DRE-216757 https://reactome.org/PathwayBrowser/#/R-DRE-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Danio rerio 15377 R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 15377 R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 15377 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 15377 R-DRE-2393939 https://reactome.org/PathwayBrowser/#/R-DRE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 15377 R-DRE-2395340 https://reactome.org/PathwayBrowser/#/R-DRE-2395340 Formation of hydroxyallysine by LOX IEA Danio rerio 15377 R-DRE-2395818 https://reactome.org/PathwayBrowser/#/R-DRE-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Danio rerio 15377 R-DRE-2395849 https://reactome.org/PathwayBrowser/#/R-DRE-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Danio rerio 15377 R-DRE-2395872 https://reactome.org/PathwayBrowser/#/R-DRE-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Danio rerio 15377 R-DRE-2395873 https://reactome.org/PathwayBrowser/#/R-DRE-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Danio rerio 15377 R-DRE-2395879 https://reactome.org/PathwayBrowser/#/R-DRE-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Danio rerio 15377 R-DRE-2395965 https://reactome.org/PathwayBrowser/#/R-DRE-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Danio rerio 15377 R-DRE-2408551 https://reactome.org/PathwayBrowser/#/R-DRE-2408551 SeMet is converted to AdoSeMet by MAT IEA Danio rerio 15377 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 15377 R-DRE-2454118 https://reactome.org/PathwayBrowser/#/R-DRE-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Danio rerio 15377 R-DRE-2465924 https://reactome.org/PathwayBrowser/#/R-DRE-2465924 OPN1LW binds 11cRAL IEA Danio rerio 15377 R-DRE-2466085 https://reactome.org/PathwayBrowser/#/R-DRE-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Danio rerio 15377 R-DRE-2509793 https://reactome.org/PathwayBrowser/#/R-DRE-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Danio rerio 15377 R-DRE-2509816 https://reactome.org/PathwayBrowser/#/R-DRE-2509816 NUDT16 hydrolyses IDP to IMP IEA Danio rerio 15377 R-DRE-2509827 https://reactome.org/PathwayBrowser/#/R-DRE-2509827 ITPA hydrolyses ITP to IMP IEA Danio rerio 15377 R-DRE-2509831 https://reactome.org/PathwayBrowser/#/R-DRE-2509831 ITPA hydrolyses XTP to XMP IEA Danio rerio 15377 R-DRE-2509838 https://reactome.org/PathwayBrowser/#/R-DRE-2509838 ITPA hydrolyses dITP to dIMP IEA Danio rerio 15377 R-DRE-2632521 https://reactome.org/PathwayBrowser/#/R-DRE-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Danio rerio 15377 R-DRE-266072 https://reactome.org/PathwayBrowser/#/R-DRE-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Danio rerio 15377 R-DRE-266082 https://reactome.org/PathwayBrowser/#/R-DRE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Danio rerio 15377 R-DRE-2995388 https://reactome.org/PathwayBrowser/#/R-DRE-2995388 PP2A dephosphorylates BANF1 IEA Danio rerio 15377 R-DRE-3002811 https://reactome.org/PathwayBrowser/#/R-DRE-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Danio rerio 15377 R-DRE-3204311 https://reactome.org/PathwayBrowser/#/R-DRE-3204311 AOX1 oxidises PXL to PDXate IEA Danio rerio 15377 R-DRE-3262512 https://reactome.org/PathwayBrowser/#/R-DRE-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Danio rerio 15377 R-DRE-3322995 https://reactome.org/PathwayBrowser/#/R-DRE-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Danio rerio 15377 R-DRE-3341296 https://reactome.org/PathwayBrowser/#/R-DRE-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Danio rerio 15377 R-DRE-3341343 https://reactome.org/PathwayBrowser/#/R-DRE-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Danio rerio 15377 R-DRE-3343700 https://reactome.org/PathwayBrowser/#/R-DRE-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Danio rerio 15377 R-DRE-350604 https://reactome.org/PathwayBrowser/#/R-DRE-350604 Agmatine + H2O <=> putrescine + urea IEA Danio rerio 15377 R-DRE-3697882 https://reactome.org/PathwayBrowser/#/R-DRE-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Danio rerio 15377 R-DRE-3697894 https://reactome.org/PathwayBrowser/#/R-DRE-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Danio rerio 15377 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 15377 R-DRE-3781018 https://reactome.org/PathwayBrowser/#/R-DRE-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Danio rerio 15377 R-DRE-3782637 https://reactome.org/PathwayBrowser/#/R-DRE-3782637 HDAC8 deacetylates histones IEA Danio rerio 15377 R-DRE-3782655 https://reactome.org/PathwayBrowser/#/R-DRE-3782655 HDAC10 deacetylates histone IEA Danio rerio 15377 R-DRE-382560 https://reactome.org/PathwayBrowser/#/R-DRE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Danio rerio 15377 R-DRE-382575 https://reactome.org/PathwayBrowser/#/R-DRE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Danio rerio 15377 R-DRE-383190 https://reactome.org/PathwayBrowser/#/R-DRE-383190 HCO3- transport through ion channel IEA Danio rerio 15377 R-DRE-389821 https://reactome.org/PathwayBrowser/#/R-DRE-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Danio rerio 15377 R-DRE-389862 https://reactome.org/PathwayBrowser/#/R-DRE-389862 Conversion of glyoxylate to oxalate IEA Danio rerio 15377 R-DRE-390304 https://reactome.org/PathwayBrowser/#/R-DRE-390304 acetyl-CoA + H2O => acetate + CoASH IEA Danio rerio 15377 R-DRE-4084976 https://reactome.org/PathwayBrowser/#/R-DRE-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Danio rerio 15377 R-DRE-4084989 https://reactome.org/PathwayBrowser/#/R-DRE-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Danio rerio 15377 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 15377 R-DRE-4085021 https://reactome.org/PathwayBrowser/#/R-DRE-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Danio rerio 15377 R-DRE-4085029 https://reactome.org/PathwayBrowser/#/R-DRE-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 15377 R-DRE-4088141 https://reactome.org/PathwayBrowser/#/R-DRE-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Danio rerio 15377 R-DRE-4093339 https://reactome.org/PathwayBrowser/#/R-DRE-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Danio rerio 15377 R-DRE-416559 https://reactome.org/PathwayBrowser/#/R-DRE-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Danio rerio 15377 R-DRE-418553 https://reactome.org/PathwayBrowser/#/R-DRE-418553 cAMP degradation by Phosphodiesterases IEA Danio rerio 15377 R-DRE-426043 https://reactome.org/PathwayBrowser/#/R-DRE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Danio rerio 15377 R-DRE-428231 https://reactome.org/PathwayBrowser/#/R-DRE-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Danio rerio 15377 R-DRE-428259 https://reactome.org/PathwayBrowser/#/R-DRE-428259 DEGS1 dehydrogenates dihydroceramide IEA Danio rerio 15377 R-DRE-428696 https://reactome.org/PathwayBrowser/#/R-DRE-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Danio rerio 15377 R-DRE-429157 https://reactome.org/PathwayBrowser/#/R-DRE-429157 ABCC4 accumulation of dense granule contents IEA Danio rerio 15377 R-DRE-429730 https://reactome.org/PathwayBrowser/#/R-DRE-429730 PPM1L dephosphorylates multiphospho-CERT1-2 IEA Danio rerio 15377 R-DRE-429860 https://reactome.org/PathwayBrowser/#/R-DRE-429860 DCP1-DCP2 complex decaps mRNA IEA Danio rerio 15377 R-DRE-432010 https://reactome.org/PathwayBrowser/#/R-DRE-432010 Aquaporin-1 passively transports water into cell IEA Danio rerio 15377 R-DRE-432054 https://reactome.org/PathwayBrowser/#/R-DRE-432054 Aquaporin-1 passively transports water out of cell IEA Danio rerio 15377 R-DRE-432065 https://reactome.org/PathwayBrowser/#/R-DRE-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Danio rerio 15377 R-DRE-445714 https://reactome.org/PathwayBrowser/#/R-DRE-445714 Aquaporin-3 passively transports water out of cell IEA Danio rerio 15377 R-DRE-446200 https://reactome.org/PathwayBrowser/#/R-DRE-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Danio rerio 15377 R-DRE-449937 https://reactome.org/PathwayBrowser/#/R-DRE-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Danio rerio 15377 R-DRE-452036 https://reactome.org/PathwayBrowser/#/R-DRE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Danio rerio 15377 R-DRE-504054 https://reactome.org/PathwayBrowser/#/R-DRE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Danio rerio 15377 R-DRE-507868 https://reactome.org/PathwayBrowser/#/R-DRE-507868 Aquaporins passively transport water into cells IEA Danio rerio 15377 R-DRE-507870 https://reactome.org/PathwayBrowser/#/R-DRE-507870 Aquaporins passively transport water out of cells IEA Danio rerio 15377 R-DRE-5223317 https://reactome.org/PathwayBrowser/#/R-DRE-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Danio rerio 15377 R-DRE-5251955 https://reactome.org/PathwayBrowser/#/R-DRE-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Danio rerio 15377 R-DRE-5251959 https://reactome.org/PathwayBrowser/#/R-DRE-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Danio rerio 15377 R-DRE-5362459 https://reactome.org/PathwayBrowser/#/R-DRE-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Danio rerio 15377 R-DRE-5362522 https://reactome.org/PathwayBrowser/#/R-DRE-5362522 ALDHs oxidise atRAL to atRA IEA Danio rerio 15377 R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 15377 R-DRE-5423647 https://reactome.org/PathwayBrowser/#/R-DRE-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Danio rerio 15377 R-DRE-5423664 https://reactome.org/PathwayBrowser/#/R-DRE-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Danio rerio 15377 R-DRE-5423672 https://reactome.org/PathwayBrowser/#/R-DRE-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Danio rerio 15377 R-DRE-5423678 https://reactome.org/PathwayBrowser/#/R-DRE-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Danio rerio 15377 R-DRE-548843 https://reactome.org/PathwayBrowser/#/R-DRE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Danio rerio 15377 R-DRE-5602295 https://reactome.org/PathwayBrowser/#/R-DRE-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Danio rerio 15377 R-DRE-5603114 https://reactome.org/PathwayBrowser/#/R-DRE-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Danio rerio 15377 R-DRE-5623513 https://reactome.org/PathwayBrowser/#/R-DRE-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Danio rerio 15377 R-DRE-5628905 https://reactome.org/PathwayBrowser/#/R-DRE-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Danio rerio 15377 R-DRE-5631885 https://reactome.org/PathwayBrowser/#/R-DRE-5631885 PRDX1 overoxidizes IEA Danio rerio 15377 R-DRE-5649705 https://reactome.org/PathwayBrowser/#/R-DRE-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Danio rerio 15377 R-DRE-5665809 https://reactome.org/PathwayBrowser/#/R-DRE-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Danio rerio 15377 R-DRE-5675373 https://reactome.org/PathwayBrowser/#/R-DRE-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Danio rerio 15377 R-DRE-5675376 https://reactome.org/PathwayBrowser/#/R-DRE-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Danio rerio 15377 R-DRE-5676637 https://reactome.org/PathwayBrowser/#/R-DRE-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Danio rerio 15377 R-DRE-5678327 https://reactome.org/PathwayBrowser/#/R-DRE-5678327 MIOX oxidises Ins to GlcA IEA Danio rerio 15377 R-DRE-5678863 https://reactome.org/PathwayBrowser/#/R-DRE-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Danio rerio 15377 R-DRE-5679041 https://reactome.org/PathwayBrowser/#/R-DRE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Danio rerio 15377 R-DRE-5687758 https://reactome.org/PathwayBrowser/#/R-DRE-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Danio rerio 15377 R-DRE-5688797 https://reactome.org/PathwayBrowser/#/R-DRE-5688797 ATXN3 family cleave Ub chains IEA Danio rerio 15377 R-DRE-5689973 https://reactome.org/PathwayBrowser/#/R-DRE-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Danio rerio 15377 R-DRE-5690042 https://reactome.org/PathwayBrowser/#/R-DRE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 15377 R-DRE-5690046 https://reactome.org/PathwayBrowser/#/R-DRE-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Danio rerio 15377 R-DRE-5690066 https://reactome.org/PathwayBrowser/#/R-DRE-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 15377 R-DRE-5690080 https://reactome.org/PathwayBrowser/#/R-DRE-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Danio rerio 15377 R-DRE-5690152 https://reactome.org/PathwayBrowser/#/R-DRE-5690152 USP5 cleaves polyubiquitin IEA Danio rerio 15377 R-DRE-5690157 https://reactome.org/PathwayBrowser/#/R-DRE-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Danio rerio 15377 R-DRE-5690319 https://reactome.org/PathwayBrowser/#/R-DRE-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Danio rerio 15377 R-DRE-5690517 https://reactome.org/PathwayBrowser/#/R-DRE-5690517 PPT1 hydrolyses palmitoylated proteins IEA Danio rerio 15377 R-DRE-5690565 https://reactome.org/PathwayBrowser/#/R-DRE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Danio rerio 15377 R-DRE-5690808 https://reactome.org/PathwayBrowser/#/R-DRE-5690808 UCHL3, SENP8 cleave NEDD8 IEA Danio rerio 15377 R-DRE-5690870 https://reactome.org/PathwayBrowser/#/R-DRE-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Danio rerio 15377 R-DRE-5691381 https://reactome.org/PathwayBrowser/#/R-DRE-5691381 MYSM1 deubiquitinates Histone H2A IEA Danio rerio 15377 R-DRE-5691507 https://reactome.org/PathwayBrowser/#/R-DRE-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Danio rerio 15377 R-DRE-5692261 https://reactome.org/PathwayBrowser/#/R-DRE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Danio rerio 15377 R-DRE-5692283 https://reactome.org/PathwayBrowser/#/R-DRE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Danio rerio 15377 R-DRE-5692480 https://reactome.org/PathwayBrowser/#/R-DRE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Danio rerio 15377 R-DRE-5692754 https://reactome.org/PathwayBrowser/#/R-DRE-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Danio rerio 15377 R-DRE-5693346 https://reactome.org/PathwayBrowser/#/R-DRE-5693346 CECRI deaminates Ade-Rib to Ino IEA Danio rerio 15377 R-DRE-5693691 https://reactome.org/PathwayBrowser/#/R-DRE-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Danio rerio 15377 R-DRE-5693724 https://reactome.org/PathwayBrowser/#/R-DRE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Danio rerio 15377 R-DRE-5693751 https://reactome.org/PathwayBrowser/#/R-DRE-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Danio rerio 15377 R-DRE-5693807 https://reactome.org/PathwayBrowser/#/R-DRE-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Danio rerio 15377 R-DRE-5694109 https://reactome.org/PathwayBrowser/#/R-DRE-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Danio rerio 15377 R-DRE-5694137 https://reactome.org/PathwayBrowser/#/R-DRE-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Danio rerio 15377 R-DRE-5694462 https://reactome.org/PathwayBrowser/#/R-DRE-5694462 ABHD6,12 hydrolyse 3AG IEA Danio rerio 15377 R-DRE-5694485 https://reactome.org/PathwayBrowser/#/R-DRE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Danio rerio 15377 R-DRE-5695964 https://reactome.org/PathwayBrowser/#/R-DRE-5695964 ABHD14B hydrolyses PNPB IEA Danio rerio 15377 R-DRE-5696049 https://reactome.org/PathwayBrowser/#/R-DRE-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 15377 R-DRE-5696080 https://reactome.org/PathwayBrowser/#/R-DRE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Danio rerio 15377 R-DRE-5696091 https://reactome.org/PathwayBrowser/#/R-DRE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Danio rerio 15377 R-DRE-5696101 https://reactome.org/PathwayBrowser/#/R-DRE-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Danio rerio 15377 R-DRE-5696119 https://reactome.org/PathwayBrowser/#/R-DRE-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Danio rerio 15377 R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 15377 R-DRE-5696197 https://reactome.org/PathwayBrowser/#/R-DRE-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Danio rerio 15377 R-DRE-5696230 https://reactome.org/PathwayBrowser/#/R-DRE-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Danio rerio 15377 R-DRE-5696365 https://reactome.org/PathwayBrowser/#/R-DRE-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Danio rerio 15377 R-DRE-5696408 https://reactome.org/PathwayBrowser/#/R-DRE-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Danio rerio 15377 R-DRE-5696415 https://reactome.org/PathwayBrowser/#/R-DRE-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Danio rerio 15377 R-DRE-5696465 https://reactome.org/PathwayBrowser/#/R-DRE-5696465 USP45 deubiquitinates ERCC1 IEA Danio rerio 15377 R-DRE-5696600 https://reactome.org/PathwayBrowser/#/R-DRE-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Danio rerio 15377 R-DRE-5696605 https://reactome.org/PathwayBrowser/#/R-DRE-5696605 USP12, USP26 deubiquitinate AR IEA Danio rerio 15377 R-DRE-5696627 https://reactome.org/PathwayBrowser/#/R-DRE-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Danio rerio 15377 R-DRE-5696872 https://reactome.org/PathwayBrowser/#/R-DRE-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Danio rerio 15377 R-DRE-5696958 https://reactome.org/PathwayBrowser/#/R-DRE-5696958 USP44 deubiquitinates CDC20 IEA Danio rerio 15377 R-DRE-5696960 https://reactome.org/PathwayBrowser/#/R-DRE-5696960 USP49 deubiquitinates H2B IEA Danio rerio 15377 R-DRE-5696968 https://reactome.org/PathwayBrowser/#/R-DRE-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Danio rerio 15377 R-DRE-5697009 https://reactome.org/PathwayBrowser/#/R-DRE-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Danio rerio 15377 R-DRE-6781764 https://reactome.org/PathwayBrowser/#/R-DRE-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Danio rerio 15377 R-DRE-6781779 https://reactome.org/PathwayBrowser/#/R-DRE-6781779 USP13 deubiquitinates BECN1,USP10 IEA Danio rerio 15377 R-DRE-6782069 https://reactome.org/PathwayBrowser/#/R-DRE-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Danio rerio 15377 R-DRE-6782820 https://reactome.org/PathwayBrowser/#/R-DRE-6782820 USP17 deubiquitinates SUDS3 IEA Danio rerio 15377 R-DRE-6783221 https://reactome.org/PathwayBrowser/#/R-DRE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Danio rerio 15377 R-DRE-6786190 https://reactome.org/PathwayBrowser/#/R-DRE-6786190 CMBL hydrolyses OM to OLMS IEA Danio rerio 15377 R-DRE-6786239 https://reactome.org/PathwayBrowser/#/R-DRE-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Danio rerio 15377 R-DRE-6786652 https://reactome.org/PathwayBrowser/#/R-DRE-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Danio rerio 15377 R-DRE-6788295 https://reactome.org/PathwayBrowser/#/R-DRE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Danio rerio 15377 R-DRE-6788912 https://reactome.org/PathwayBrowser/#/R-DRE-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Danio rerio 15377 R-DRE-6789310 https://reactome.org/PathwayBrowser/#/R-DRE-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Danio rerio 15377 R-DRE-6792445 https://reactome.org/PathwayBrowser/#/R-DRE-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Danio rerio 15377 R-DRE-6797913 https://reactome.org/PathwayBrowser/#/R-DRE-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Danio rerio 15377 R-DRE-6797955 https://reactome.org/PathwayBrowser/#/R-DRE-6797955 ALDH7A1 oxidises BETALD to BET IEA Danio rerio 15377 R-DRE-6799604 https://reactome.org/PathwayBrowser/#/R-DRE-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Danio rerio 15377 R-DRE-6799695 https://reactome.org/PathwayBrowser/#/R-DRE-6799695 GPX5,6 reduce H2O2 to H2O IEA Danio rerio 15377 R-DRE-6799977 https://reactome.org/PathwayBrowser/#/R-DRE-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Danio rerio 15377 R-DRE-6800198 https://reactome.org/PathwayBrowser/#/R-DRE-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Danio rerio 15377 R-DRE-6801462 https://reactome.org/PathwayBrowser/#/R-DRE-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Danio rerio 15377 R-DRE-6803545 https://reactome.org/PathwayBrowser/#/R-DRE-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Danio rerio 15377 R-DRE-6803789 https://reactome.org/PathwayBrowser/#/R-DRE-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Danio rerio 15377 R-DRE-6807053 https://reactome.org/PathwayBrowser/#/R-DRE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Danio rerio 15377 R-DRE-6807206 https://reactome.org/PathwayBrowser/#/R-DRE-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Danio rerio 15377 R-DRE-6808464 https://reactome.org/PathwayBrowser/#/R-DRE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Danio rerio 15377 R-DRE-6808496 https://reactome.org/PathwayBrowser/#/R-DRE-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Danio rerio 15377 R-DRE-6809263 https://reactome.org/PathwayBrowser/#/R-DRE-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Danio rerio 15377 R-DRE-6809287 https://reactome.org/PathwayBrowser/#/R-DRE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Danio rerio 15377 R-DRE-6809320 https://reactome.org/PathwayBrowser/#/R-DRE-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Danio rerio 15377 R-DRE-6809325 https://reactome.org/PathwayBrowser/#/R-DRE-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Danio rerio 15377 R-DRE-6809720 https://reactome.org/PathwayBrowser/#/R-DRE-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Danio rerio 15377 R-DRE-6810410 https://reactome.org/PathwayBrowser/#/R-DRE-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Danio rerio 15377 R-DRE-6810464 https://reactome.org/PathwayBrowser/#/R-DRE-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Danio rerio 15377 R-DRE-6810474 https://reactome.org/PathwayBrowser/#/R-DRE-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Danio rerio 15377 R-DRE-6811504 https://reactome.org/PathwayBrowser/#/R-DRE-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Danio rerio 15377 R-DRE-6813720 https://reactome.org/PathwayBrowser/#/R-DRE-6813720 NCEH1 hydrolyzes cholesterol esters IEA Danio rerio 15377 R-DRE-6813740 https://reactome.org/PathwayBrowser/#/R-DRE-6813740 GDE1 hydrolyzes GroPIns IEA Danio rerio 15377 R-DRE-6814797 https://reactome.org/PathwayBrowser/#/R-DRE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Danio rerio 15377 R-DRE-70479 https://reactome.org/PathwayBrowser/#/R-DRE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Danio rerio 15377 R-DRE-70494 https://reactome.org/PathwayBrowser/#/R-DRE-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Danio rerio 15377 R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Danio rerio 15377 R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Danio rerio 15377 R-DRE-70609 https://reactome.org/PathwayBrowser/#/R-DRE-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Danio rerio 15377 R-DRE-70679 https://reactome.org/PathwayBrowser/#/R-DRE-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Danio rerio 15377 R-DRE-70881 https://reactome.org/PathwayBrowser/#/R-DRE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Danio rerio 15377 R-DRE-70903 https://reactome.org/PathwayBrowser/#/R-DRE-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Danio rerio 15377 R-DRE-70906 https://reactome.org/PathwayBrowser/#/R-DRE-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Danio rerio 15377 R-DRE-70938 https://reactome.org/PathwayBrowser/#/R-DRE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Danio rerio 15377 R-DRE-70940 https://reactome.org/PathwayBrowser/#/R-DRE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Danio rerio 15377 R-DRE-70941 https://reactome.org/PathwayBrowser/#/R-DRE-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Danio rerio 15377 R-DRE-70975 https://reactome.org/PathwayBrowser/#/R-DRE-70975 CS acetylates OA to citrate IEA Danio rerio 15377 R-DRE-70982 https://reactome.org/PathwayBrowser/#/R-DRE-70982 FH tetramer hydrates fumarate to L-malate IEA Danio rerio 15377 R-DRE-71146 https://reactome.org/PathwayBrowser/#/R-DRE-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Danio rerio 15377 R-DRE-71200 https://reactome.org/PathwayBrowser/#/R-DRE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Danio rerio 15377 R-DRE-71260 https://reactome.org/PathwayBrowser/#/R-DRE-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Danio rerio 15377 R-DRE-71660 https://reactome.org/PathwayBrowser/#/R-DRE-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Danio rerio 15377 R-DRE-71723 https://reactome.org/PathwayBrowser/#/R-DRE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Danio rerio 15377 R-DRE-71732 https://reactome.org/PathwayBrowser/#/R-DRE-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Danio rerio 15377 R-DRE-73589 https://reactome.org/PathwayBrowser/#/R-DRE-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Danio rerio 15377 R-DRE-73591 https://reactome.org/PathwayBrowser/#/R-DRE-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Danio rerio 15377 R-DRE-73596 https://reactome.org/PathwayBrowser/#/R-DRE-73596 dCMP + H2O => dUMP + NH4+ IEA Danio rerio 15377 R-DRE-73608 https://reactome.org/PathwayBrowser/#/R-DRE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Danio rerio 15377 R-DRE-73618 https://reactome.org/PathwayBrowser/#/R-DRE-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Danio rerio 15377 R-DRE-73620 https://reactome.org/PathwayBrowser/#/R-DRE-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Danio rerio 15377 R-DRE-73647 https://reactome.org/PathwayBrowser/#/R-DRE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Danio rerio 15377 R-DRE-73666 https://reactome.org/PathwayBrowser/#/R-DRE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Danio rerio 15377 R-DRE-73794 https://reactome.org/PathwayBrowser/#/R-DRE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Danio rerio 15377 R-DRE-73797 https://reactome.org/PathwayBrowser/#/R-DRE-73797 FAICAR => IMP + H2O IEA Danio rerio 15377 R-DRE-73815 https://reactome.org/PathwayBrowser/#/R-DRE-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Danio rerio 15377 R-DRE-74241 https://reactome.org/PathwayBrowser/#/R-DRE-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Danio rerio 15377 R-DRE-74255 https://reactome.org/PathwayBrowser/#/R-DRE-74255 Guanine + H2O => Xanthine + NH4+ IEA Danio rerio 15377 R-DRE-75872 https://reactome.org/PathwayBrowser/#/R-DRE-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Danio rerio 15377 R-DRE-76031 https://reactome.org/PathwayBrowser/#/R-DRE-76031 2 H2O2 => O2 + 2 H2O IEA Danio rerio 15377 R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 15377 R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 15377 R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 15377 R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 15377 R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 15377 R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 15377 R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 15377 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 15377 R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 15377 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 15377 R-DRE-76590 https://reactome.org/PathwayBrowser/#/R-DRE-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Danio rerio 15377 R-DRE-77277 https://reactome.org/PathwayBrowser/#/R-DRE-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Danio rerio 15377 R-DRE-77301 https://reactome.org/PathwayBrowser/#/R-DRE-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Danio rerio 15377 R-DRE-8848215 https://reactome.org/PathwayBrowser/#/R-DRE-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Danio rerio 15377 R-DRE-8848339 https://reactome.org/PathwayBrowser/#/R-DRE-8848339 PNPLA5 hydrolyzes TAG IEA Danio rerio 15377 R-DRE-8848484 https://reactome.org/PathwayBrowser/#/R-DRE-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Danio rerio 15377 R-DRE-8849969 https://reactome.org/PathwayBrowser/#/R-DRE-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Danio rerio 15377 R-DRE-8850594 https://reactome.org/PathwayBrowser/#/R-DRE-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Danio rerio 15377 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 15377 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 15377 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 15377 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 15377 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 15377 R-DRE-8854173 https://reactome.org/PathwayBrowser/#/R-DRE-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Danio rerio 15377 R-DRE-8854255 https://reactome.org/PathwayBrowser/#/R-DRE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Danio rerio 15377 R-DRE-8854329 https://reactome.org/PathwayBrowser/#/R-DRE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Danio rerio 15377 R-DRE-8854604 https://reactome.org/PathwayBrowser/#/R-DRE-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Danio rerio 15377 R-DRE-8854612 https://reactome.org/PathwayBrowser/#/R-DRE-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Danio rerio 15377 R-DRE-8856951 https://reactome.org/PathwayBrowser/#/R-DRE-8856951 PP2A demethylation by PPME1 IEA Danio rerio 15377 R-DRE-8862320 https://reactome.org/PathwayBrowser/#/R-DRE-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Danio rerio 15377 R-DRE-8863804 https://reactome.org/PathwayBrowser/#/R-DRE-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Danio rerio 15377 R-DRE-8864036 https://reactome.org/PathwayBrowser/#/R-DRE-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Danio rerio 15377 R-DRE-8864125 https://reactome.org/PathwayBrowser/#/R-DRE-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Danio rerio 15377 R-DRE-8866405 https://reactome.org/PathwayBrowser/#/R-DRE-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 15377 R-DRE-8866601 https://reactome.org/PathwayBrowser/#/R-DRE-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Danio rerio 15377 R-DRE-8867344 https://reactome.org/PathwayBrowser/#/R-DRE-8867344 OMA1 hydrolyses OPA1 IEA Danio rerio 15377 R-DRE-8869425 https://reactome.org/PathwayBrowser/#/R-DRE-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Danio rerio 15377 R-DRE-8869506 https://reactome.org/PathwayBrowser/#/R-DRE-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Danio rerio 15377 R-DRE-8874435 https://reactome.org/PathwayBrowser/#/R-DRE-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Danio rerio 15377 R-DRE-8878581 https://reactome.org/PathwayBrowser/#/R-DRE-8878581 TYRP1 oxidises DHICA to IQCA IEA Danio rerio 15377 R-DRE-8878654 https://reactome.org/PathwayBrowser/#/R-DRE-8878654 ACP6 hydrolyses MYS-LPA IEA Danio rerio 15377 R-DRE-8878787 https://reactome.org/PathwayBrowser/#/R-DRE-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Danio rerio 15377 R-DRE-8932633 https://reactome.org/PathwayBrowser/#/R-DRE-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Danio rerio 15377 R-DRE-8933328 https://reactome.org/PathwayBrowser/#/R-DRE-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Danio rerio 15377 R-DRE-8936442 https://reactome.org/PathwayBrowser/#/R-DRE-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Danio rerio 15377 R-DRE-8937442 https://reactome.org/PathwayBrowser/#/R-DRE-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Danio rerio 15377 R-DRE-8940070 https://reactome.org/PathwayBrowser/#/R-DRE-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Danio rerio 15377 R-DRE-8940074 https://reactome.org/PathwayBrowser/#/R-DRE-8940074 NT5E:Zn2+ hydrolyses NMN IEA Danio rerio 15377 R-DRE-8952137 https://reactome.org/PathwayBrowser/#/R-DRE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Danio rerio 15377 R-DRE-8952903 https://reactome.org/PathwayBrowser/#/R-DRE-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Danio rerio 15377 R-DRE-8953339 https://reactome.org/PathwayBrowser/#/R-DRE-8953339 DNPH1 hydrolyses dGMP IEA Danio rerio 15377 R-DRE-8953499 https://reactome.org/PathwayBrowser/#/R-DRE-8953499 IMPAD1 hydrolyses PAP to AMP IEA Danio rerio 15377 R-DRE-8954398 https://reactome.org/PathwayBrowser/#/R-DRE-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Danio rerio 15377 R-DRE-8959510 https://reactome.org/PathwayBrowser/#/R-DRE-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Danio rerio 15377 R-DRE-8980228 https://reactome.org/PathwayBrowser/#/R-DRE-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Danio rerio 15377 R-DRE-8981637 https://reactome.org/PathwayBrowser/#/R-DRE-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Danio rerio 15377 R-DRE-9013144 https://reactome.org/PathwayBrowser/#/R-DRE-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Danio rerio 15377 R-DRE-9013161 https://reactome.org/PathwayBrowser/#/R-DRE-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Danio rerio 15377 R-DRE-9013437 https://reactome.org/PathwayBrowser/#/R-DRE-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Danio rerio 15377 R-DRE-9014295 https://reactome.org/PathwayBrowser/#/R-DRE-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Danio rerio 15377 R-DRE-9014434 https://reactome.org/PathwayBrowser/#/R-DRE-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Danio rerio 15377 R-DRE-9018745 https://reactome.org/PathwayBrowser/#/R-DRE-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Danio rerio 15377 R-DRE-9018806 https://reactome.org/PathwayBrowser/#/R-DRE-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Danio rerio 15377 R-DRE-9018814 https://reactome.org/PathwayBrowser/#/R-DRE-9018814 RHOT1 hydrolyzes GTP IEA Danio rerio 15377 R-DRE-9018826 https://reactome.org/PathwayBrowser/#/R-DRE-9018826 RHOT2 hydrolyzes GTP IEA Danio rerio 15377 R-DRE-9018862 https://reactome.org/PathwayBrowser/#/R-DRE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Danio rerio 15377 R-DRE-9018877 https://reactome.org/PathwayBrowser/#/R-DRE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Danio rerio 15377 R-DRE-9020252 https://reactome.org/PathwayBrowser/#/R-DRE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Danio rerio 15377 R-DRE-9020253 https://reactome.org/PathwayBrowser/#/R-DRE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Danio rerio 15377 R-DRE-9020257 https://reactome.org/PathwayBrowser/#/R-DRE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Danio rerio 15377 R-DRE-9020258 https://reactome.org/PathwayBrowser/#/R-DRE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Danio rerio 15377 R-DRE-9020270 https://reactome.org/PathwayBrowser/#/R-DRE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Danio rerio 15377 R-DRE-9024890 https://reactome.org/PathwayBrowser/#/R-DRE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Danio rerio 15377 R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio 15377 R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 15377 R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 15377 R-DRE-9033520 https://reactome.org/PathwayBrowser/#/R-DRE-9033520 TYSND1 cleaves TYSND1 IEA Danio rerio 15377 R-DRE-9037761 https://reactome.org/PathwayBrowser/#/R-DRE-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Danio rerio 15377 R-DRE-917841 https://reactome.org/PathwayBrowser/#/R-DRE-917841 Acidification of Tf:TfR1 containing endosome IEA Danio rerio 15377 R-DRE-917891 https://reactome.org/PathwayBrowser/#/R-DRE-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Danio rerio 15377 R-DRE-936802 https://reactome.org/PathwayBrowser/#/R-DRE-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Danio rerio 15377 R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 15377 R-DRE-939763 https://reactome.org/PathwayBrowser/#/R-DRE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Danio rerio 15377 R-DRE-947591 https://reactome.org/PathwayBrowser/#/R-DRE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Danio rerio 15377 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 15377 R-DRE-9620103 https://reactome.org/PathwayBrowser/#/R-DRE-9620103 ALDH2 transforms GTN to NO IEA Danio rerio 15377 R-DRE-9624893 https://reactome.org/PathwayBrowser/#/R-DRE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Danio rerio 15377 R-DRE-9638046 https://reactome.org/PathwayBrowser/#/R-DRE-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Danio rerio 15377 R-DRE-9647994 https://reactome.org/PathwayBrowser/#/R-DRE-9647994 RAS proteins are depalmitoylated IEA Danio rerio 15377 R-DRE-9656891 https://reactome.org/PathwayBrowser/#/R-DRE-9656891 OPN1SW binds 11cRAL IEA Danio rerio 15377 R-DRE-9656893 https://reactome.org/PathwayBrowser/#/R-DRE-9656893 OPN1MW binds 11cRAL IEA Danio rerio 15377 R-DRE-9658445 https://reactome.org/PathwayBrowser/#/R-DRE-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Danio rerio 15377 R-DRE-9667952 https://reactome.org/PathwayBrowser/#/R-DRE-9667952 ANKLE2 is deacetylated by SIRT2 IEA Danio rerio 15377 R-DRE-9673053 https://reactome.org/PathwayBrowser/#/R-DRE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Danio rerio 15377 R-DRE-9673054 https://reactome.org/PathwayBrowser/#/R-DRE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Danio rerio 15377 R-DRE-9693282 https://reactome.org/PathwayBrowser/#/R-DRE-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Danio rerio 15377 R-DRE-9709360 https://reactome.org/PathwayBrowser/#/R-DRE-9709360 H2O2 reduces MetHb IEA Danio rerio 15377 R-DRE-9727567 https://reactome.org/PathwayBrowser/#/R-DRE-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Danio rerio 15377 R-DRE-9731228 https://reactome.org/PathwayBrowser/#/R-DRE-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Danio rerio 15377 R-DRE-9731590 https://reactome.org/PathwayBrowser/#/R-DRE-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Danio rerio 15377 R-DRE-9731613 https://reactome.org/PathwayBrowser/#/R-DRE-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Danio rerio 15377 R-DRE-9731632 https://reactome.org/PathwayBrowser/#/R-DRE-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Danio rerio 15377 R-DRE-9731661 https://reactome.org/PathwayBrowser/#/R-DRE-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Danio rerio 15377 R-DRE-9748945 https://reactome.org/PathwayBrowser/#/R-DRE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Danio rerio 15377 R-DRE-9749647 https://reactome.org/PathwayBrowser/#/R-DRE-9749647 CES2 hydrolyzes ASA- IEA Danio rerio 15377 R-DRE-9749792 https://reactome.org/PathwayBrowser/#/R-DRE-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Danio rerio 15377 R-DRE-9749986 https://reactome.org/PathwayBrowser/#/R-DRE-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Danio rerio 15377 R-DRE-9750016 https://reactome.org/PathwayBrowser/#/R-DRE-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Danio rerio 15377 R-DRE-9750546 https://reactome.org/PathwayBrowser/#/R-DRE-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 15377 R-DRE-9750617 https://reactome.org/PathwayBrowser/#/R-DRE-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 15377 R-DRE-9750656 https://reactome.org/PathwayBrowser/#/R-DRE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Danio rerio 15377 R-DRE-9753278 https://reactome.org/PathwayBrowser/#/R-DRE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 15377 R-DRE-9753280 https://reactome.org/PathwayBrowser/#/R-DRE-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Danio rerio 15377 R-DRE-9753283 https://reactome.org/PathwayBrowser/#/R-DRE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 15377 R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 15377 R-DRE-9753285 https://reactome.org/PathwayBrowser/#/R-DRE-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Danio rerio 15377 R-DRE-9753632 https://reactome.org/PathwayBrowser/#/R-DRE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Danio rerio 15377 R-DRE-9754964 https://reactome.org/PathwayBrowser/#/R-DRE-9754964 ADA deamidates RBV IEA Danio rerio 15377 R-DRE-9755030 https://reactome.org/PathwayBrowser/#/R-DRE-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Danio rerio 15377 R-DRE-9756138 https://reactome.org/PathwayBrowser/#/R-DRE-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Danio rerio 15377 R-DRE-9756162 https://reactome.org/PathwayBrowser/#/R-DRE-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Danio rerio 15377 R-DRE-9756169 https://reactome.org/PathwayBrowser/#/R-DRE-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Danio rerio 15377 R-DRE-9756177 https://reactome.org/PathwayBrowser/#/R-DRE-9756177 PON1,3 hydrolyse ATVL to ATV IEA Danio rerio 15377 R-DRE-9756180 https://reactome.org/PathwayBrowser/#/R-DRE-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Danio rerio 15377 R-DRE-9758674 https://reactome.org/PathwayBrowser/#/R-DRE-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Danio rerio 15377 R-DRE-977324 https://reactome.org/PathwayBrowser/#/R-DRE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Danio rerio 15377 R-DRE-9839105 https://reactome.org/PathwayBrowser/#/R-DRE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Danio rerio 15377 R-DRE-9839113 https://reactome.org/PathwayBrowser/#/R-DRE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Danio rerio 15377 R-DRE-9840408 https://reactome.org/PathwayBrowser/#/R-DRE-9840408 OMA1 cleaves DELE1 IEA Danio rerio 15377 R-DRE-9861626 https://reactome.org/PathwayBrowser/#/R-DRE-9861626 SIRT4 cleaves lipoyl from DLAT IEA Danio rerio 15377 R-DRE-9861725 https://reactome.org/PathwayBrowser/#/R-DRE-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Danio rerio 15377 R-DRE-997326 https://reactome.org/PathwayBrowser/#/R-DRE-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Danio rerio 15377 R-FCA-164926 https://reactome.org/PathwayBrowser/#/R-FCA-164926 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ TAS Felis catus 15377 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 15377 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 15377 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 15377 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 15377 R-GGA-109415 https://reactome.org/PathwayBrowser/#/R-GGA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Gallus gallus 15377 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 15377 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 15377 R-GGA-111879 https://reactome.org/PathwayBrowser/#/R-GGA-111879 PIP2 hydrolysis IEA Gallus gallus 15377 R-GGA-111883 https://reactome.org/PathwayBrowser/#/R-GGA-111883 Hydrolysis of phosphatidylcholine IEA Gallus gallus 15377 R-GGA-111955 https://reactome.org/PathwayBrowser/#/R-GGA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Gallus gallus 15377 R-GGA-111962 https://reactome.org/PathwayBrowser/#/R-GGA-111962 PDE4A,C,D hydrolyse cAMP IEA Gallus gallus 15377 R-GGA-112037 https://reactome.org/PathwayBrowser/#/R-GGA-112037 Inactivation of PLC beta IEA Gallus gallus 15377 R-GGA-1169192 https://reactome.org/PathwayBrowser/#/R-GGA-1169192 PTP1B dephosphorylates GHR IEA Gallus gallus 15377 R-GGA-1183128 https://reactome.org/PathwayBrowser/#/R-GGA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Gallus gallus 15377 R-GGA-1237045 https://reactome.org/PathwayBrowser/#/R-GGA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Gallus gallus 15377 R-GGA-1237047 https://reactome.org/PathwayBrowser/#/R-GGA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Gallus gallus 15377 R-GGA-1237059 https://reactome.org/PathwayBrowser/#/R-GGA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Gallus gallus 15377 R-GGA-1237081 https://reactome.org/PathwayBrowser/#/R-GGA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Gallus gallus 15377 R-GGA-1237129 https://reactome.org/PathwayBrowser/#/R-GGA-1237129 Acireductone is created IEA Gallus gallus 15377 R-GGA-1247910 https://reactome.org/PathwayBrowser/#/R-GGA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Gallus gallus 15377 R-GGA-1369028 https://reactome.org/PathwayBrowser/#/R-GGA-1369028 ABCAs mediate lipid efflux IEA Gallus gallus 15377 R-GGA-1369052 https://reactome.org/PathwayBrowser/#/R-GGA-1369052 ABCAs mediate lipid influx IEA Gallus gallus 15377 R-GGA-1369065 https://reactome.org/PathwayBrowser/#/R-GGA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Gallus gallus 15377 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 15377 R-GGA-140359 https://reactome.org/PathwayBrowser/#/R-GGA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Gallus gallus 15377 R-GGA-141186 https://reactome.org/PathwayBrowser/#/R-GGA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Gallus gallus 15377 R-GGA-141200 https://reactome.org/PathwayBrowser/#/R-GGA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Gallus gallus 15377 R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus 15377 R-GGA-141341 https://reactome.org/PathwayBrowser/#/R-GGA-141341 SMOX-3 oxidises SPN to SPM IEA Gallus gallus 15377 R-GGA-141348 https://reactome.org/PathwayBrowser/#/R-GGA-141348 PAO:FAD oxidises NASPM to PTCN IEA Gallus gallus 15377 R-GGA-141351 https://reactome.org/PathwayBrowser/#/R-GGA-141351 PAOX:FAD oxidises NASPN to SPM IEA Gallus gallus 15377 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 15377 R-GGA-1454916 https://reactome.org/PathwayBrowser/#/R-GGA-1454916 The ABCC family mediates organic anion transport IEA Gallus gallus 15377 R-GGA-1454928 https://reactome.org/PathwayBrowser/#/R-GGA-1454928 ABCG4 may mediate cholesterol efflux IEA Gallus gallus 15377 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 15377 R-GGA-1467466 https://reactome.org/PathwayBrowser/#/R-GGA-1467466 ABCA4 mediates atRAL transport IEA Gallus gallus 15377 R-GGA-1474146 https://reactome.org/PathwayBrowser/#/R-GGA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Gallus gallus 15377 R-GGA-1475017 https://reactome.org/PathwayBrowser/#/R-GGA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Gallus gallus 15377 R-GGA-1475022 https://reactome.org/PathwayBrowser/#/R-GGA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Gallus gallus 15377 R-GGA-1475025 https://reactome.org/PathwayBrowser/#/R-GGA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Gallus gallus 15377 R-GGA-1475026 https://reactome.org/PathwayBrowser/#/R-GGA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Gallus gallus 15377 R-GGA-1475028 https://reactome.org/PathwayBrowser/#/R-GGA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Gallus gallus 15377 R-GGA-1475032 https://reactome.org/PathwayBrowser/#/R-GGA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Gallus gallus 15377 R-GGA-1475435 https://reactome.org/PathwayBrowser/#/R-GGA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Gallus gallus 15377 R-GGA-1475436 https://reactome.org/PathwayBrowser/#/R-GGA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Gallus gallus 15377 R-GGA-1482543 https://reactome.org/PathwayBrowser/#/R-GGA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Gallus gallus 15377 R-GGA-1482604 https://reactome.org/PathwayBrowser/#/R-GGA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Gallus gallus 15377 R-GGA-1482612 https://reactome.org/PathwayBrowser/#/R-GGA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 15377 R-GGA-1482656 https://reactome.org/PathwayBrowser/#/R-GGA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Gallus gallus 15377 R-GGA-1482679 https://reactome.org/PathwayBrowser/#/R-GGA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Gallus gallus 15377 R-GGA-1482685 https://reactome.org/PathwayBrowser/#/R-GGA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 15377 R-GGA-1482745 https://reactome.org/PathwayBrowser/#/R-GGA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Gallus gallus 15377 R-GGA-1482759 https://reactome.org/PathwayBrowser/#/R-GGA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Gallus gallus 15377 R-GGA-1482771 https://reactome.org/PathwayBrowser/#/R-GGA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Gallus gallus 15377 R-GGA-1482776 https://reactome.org/PathwayBrowser/#/R-GGA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Gallus gallus 15377 R-GGA-1482777 https://reactome.org/PathwayBrowser/#/R-GGA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Gallus gallus 15377 R-GGA-1482811 https://reactome.org/PathwayBrowser/#/R-GGA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Gallus gallus 15377 R-GGA-1482816 https://reactome.org/PathwayBrowser/#/R-GGA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Gallus gallus 15377 R-GGA-1482825 https://reactome.org/PathwayBrowser/#/R-GGA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Gallus gallus 15377 R-GGA-1482828 https://reactome.org/PathwayBrowser/#/R-GGA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Gallus gallus 15377 R-GGA-1482847 https://reactome.org/PathwayBrowser/#/R-GGA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Gallus gallus 15377 R-GGA-1482856 https://reactome.org/PathwayBrowser/#/R-GGA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Gallus gallus 15377 R-GGA-1482862 https://reactome.org/PathwayBrowser/#/R-GGA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Gallus gallus 15377 R-GGA-1482868 https://reactome.org/PathwayBrowser/#/R-GGA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Gallus gallus 15377 R-GGA-1482884 https://reactome.org/PathwayBrowser/#/R-GGA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Gallus gallus 15377 R-GGA-1482887 https://reactome.org/PathwayBrowser/#/R-GGA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Gallus gallus 15377 R-GGA-1482897 https://reactome.org/PathwayBrowser/#/R-GGA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Gallus gallus 15377 R-GGA-1482900 https://reactome.org/PathwayBrowser/#/R-GGA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Gallus gallus 15377 R-GGA-1482907 https://reactome.org/PathwayBrowser/#/R-GGA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Gallus gallus 15377 R-GGA-1482920 https://reactome.org/PathwayBrowser/#/R-GGA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Gallus gallus 15377 R-GGA-1482932 https://reactome.org/PathwayBrowser/#/R-GGA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Gallus gallus 15377 R-GGA-1483096 https://reactome.org/PathwayBrowser/#/R-GGA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Gallus gallus 15377 R-GGA-1483159 https://reactome.org/PathwayBrowser/#/R-GGA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Gallus gallus 15377 R-GGA-1483182 https://reactome.org/PathwayBrowser/#/R-GGA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Gallus gallus 15377 R-GGA-1483203 https://reactome.org/PathwayBrowser/#/R-GGA-1483203 PA is dephosphorylated to DAG by LPIN IEA Gallus gallus 15377 R-GGA-156526 https://reactome.org/PathwayBrowser/#/R-GGA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Gallus gallus 15377 R-GGA-159425 https://reactome.org/PathwayBrowser/#/R-GGA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 15377 R-GGA-1602368 https://reactome.org/PathwayBrowser/#/R-GGA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Gallus gallus 15377 R-GGA-1602374 https://reactome.org/PathwayBrowser/#/R-GGA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Gallus gallus 15377 R-GGA-1602377 https://reactome.org/PathwayBrowser/#/R-GGA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Gallus gallus 15377 R-GGA-1602398 https://reactome.org/PathwayBrowser/#/R-GGA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Gallus gallus 15377 R-GGA-1602399 https://reactome.org/PathwayBrowser/#/R-GGA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Gallus gallus 15377 R-GGA-1602417 https://reactome.org/PathwayBrowser/#/R-GGA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Gallus gallus 15377 R-GGA-1602446 https://reactome.org/PathwayBrowser/#/R-GGA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Gallus gallus 15377 R-GGA-1605591 https://reactome.org/PathwayBrowser/#/R-GGA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Gallus gallus 15377 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus 15377 R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus 15377 R-GGA-1605723 https://reactome.org/PathwayBrowser/#/R-GGA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Gallus gallus 15377 R-GGA-1605724 https://reactome.org/PathwayBrowser/#/R-GGA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Gallus gallus 15377 R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus 15377 R-GGA-1605768 https://reactome.org/PathwayBrowser/#/R-GGA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Gallus gallus 15377 R-GGA-1605797 https://reactome.org/PathwayBrowser/#/R-GGA-1605797 SMPD1 hydrolyzes SPHM IEA Gallus gallus 15377 R-GGA-1606273 https://reactome.org/PathwayBrowser/#/R-GGA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Gallus gallus 15377 R-GGA-1606288 https://reactome.org/PathwayBrowser/#/R-GGA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Gallus gallus 15377 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus 15377 R-GGA-1606564 https://reactome.org/PathwayBrowser/#/R-GGA-1606564 GALC hydrolyzes GalCer IEA Gallus gallus 15377 R-GGA-1606583 https://reactome.org/PathwayBrowser/#/R-GGA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Gallus gallus 15377 R-GGA-1606602 https://reactome.org/PathwayBrowser/#/R-GGA-1606602 ASAH1 hydrolyzes ceramide IEA Gallus gallus 15377 R-GGA-1606789 https://reactome.org/PathwayBrowser/#/R-GGA-1606789 ARSB hydrolyses DS IEA Gallus gallus 15377 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 15377 R-GGA-1606839 https://reactome.org/PathwayBrowser/#/R-GGA-1606839 ARSC hydrolyzes steroid sulfates IEA Gallus gallus 15377 R-GGA-1614524 https://reactome.org/PathwayBrowser/#/R-GGA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Gallus gallus 15377 R-GGA-1614544 https://reactome.org/PathwayBrowser/#/R-GGA-1614544 Sulfite is oxidized to sulfate IEA Gallus gallus 15377 R-GGA-1614583 https://reactome.org/PathwayBrowser/#/R-GGA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Gallus gallus 15377 R-GGA-1614614 https://reactome.org/PathwayBrowser/#/R-GGA-1614614 Cysteine is degraded to serine and H2S IEA Gallus gallus 15377 R-GGA-1614631 https://reactome.org/PathwayBrowser/#/R-GGA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Gallus gallus 15377 R-GGA-162425 https://reactome.org/PathwayBrowser/#/R-GGA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Gallus gallus 15377 R-GGA-162857 https://reactome.org/PathwayBrowser/#/R-GGA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Gallus gallus 15377 R-GGA-1630304 https://reactome.org/PathwayBrowser/#/R-GGA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Gallus gallus 15377 R-GGA-1630306 https://reactome.org/PathwayBrowser/#/R-GGA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Gallus gallus 15377 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 15377 R-GGA-1638032 https://reactome.org/PathwayBrowser/#/R-GGA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Gallus gallus 15377 R-GGA-1638053 https://reactome.org/PathwayBrowser/#/R-GGA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Gallus gallus 15377 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus 15377 R-GGA-1640164 https://reactome.org/PathwayBrowser/#/R-GGA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Gallus gallus 15377 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus 15377 R-GGA-1667005 https://reactome.org/PathwayBrowser/#/R-GGA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Gallus gallus 15377 R-GGA-1675795 https://reactome.org/PathwayBrowser/#/R-GGA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Gallus gallus 15377 R-GGA-1675824 https://reactome.org/PathwayBrowser/#/R-GGA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Gallus gallus 15377 R-GGA-1675836 https://reactome.org/PathwayBrowser/#/R-GGA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Gallus gallus 15377 R-GGA-1675949 https://reactome.org/PathwayBrowser/#/R-GGA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Gallus gallus 15377 R-GGA-1675988 https://reactome.org/PathwayBrowser/#/R-GGA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Gallus gallus 15377 R-GGA-1675994 https://reactome.org/PathwayBrowser/#/R-GGA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Gallus gallus 15377 R-GGA-1676005 https://reactome.org/PathwayBrowser/#/R-GGA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Gallus gallus 15377 R-GGA-1676020 https://reactome.org/PathwayBrowser/#/R-GGA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Gallus gallus 15377 R-GGA-1676065 https://reactome.org/PathwayBrowser/#/R-GGA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Gallus gallus 15377 R-GGA-1676105 https://reactome.org/PathwayBrowser/#/R-GGA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Gallus gallus 15377 R-GGA-1676114 https://reactome.org/PathwayBrowser/#/R-GGA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Gallus gallus 15377 R-GGA-1676124 https://reactome.org/PathwayBrowser/#/R-GGA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Gallus gallus 15377 R-GGA-1676141 https://reactome.org/PathwayBrowser/#/R-GGA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Gallus gallus 15377 R-GGA-1676149 https://reactome.org/PathwayBrowser/#/R-GGA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Gallus gallus 15377 R-GGA-1676162 https://reactome.org/PathwayBrowser/#/R-GGA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Gallus gallus 15377 R-GGA-1676164 https://reactome.org/PathwayBrowser/#/R-GGA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Gallus gallus 15377 R-GGA-1676174 https://reactome.org/PathwayBrowser/#/R-GGA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Gallus gallus 15377 R-GGA-1676177 https://reactome.org/PathwayBrowser/#/R-GGA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Gallus gallus 15377 R-GGA-1676203 https://reactome.org/PathwayBrowser/#/R-GGA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Gallus gallus 15377 R-GGA-1676204 https://reactome.org/PathwayBrowser/#/R-GGA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Gallus gallus 15377 R-GGA-1678650 https://reactome.org/PathwayBrowser/#/R-GGA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Gallus gallus 15377 R-GGA-1678708 https://reactome.org/PathwayBrowser/#/R-GGA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Gallus gallus 15377 R-GGA-1678716 https://reactome.org/PathwayBrowser/#/R-GGA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Gallus gallus 15377 R-GGA-1678742 https://reactome.org/PathwayBrowser/#/R-GGA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Gallus gallus 15377 R-GGA-1678854 https://reactome.org/PathwayBrowser/#/R-GGA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Gallus gallus 15377 R-GGA-170158 https://reactome.org/PathwayBrowser/#/R-GGA-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Gallus gallus 15377 R-GGA-170161 https://reactome.org/PathwayBrowser/#/R-GGA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Gallus gallus 15377 R-GGA-173597 https://reactome.org/PathwayBrowser/#/R-GGA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Gallus gallus 15377 R-GGA-173739 https://reactome.org/PathwayBrowser/#/R-GGA-173739 Spontaneous hydrolysis of C3 thioester IEA Gallus gallus 15377 R-GGA-174110 https://reactome.org/PathwayBrowser/#/R-GGA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Gallus gallus 15377 R-GGA-174124 https://reactome.org/PathwayBrowser/#/R-GGA-174124 Dephosphorylation of phospho-Cdh1 IEA Gallus gallus 15377 R-GGA-174391 https://reactome.org/PathwayBrowser/#/R-GGA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Gallus gallus 15377 R-GGA-174401 https://reactome.org/PathwayBrowser/#/R-GGA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Gallus gallus 15377 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus 15377 R-GGA-176606 https://reactome.org/PathwayBrowser/#/R-GGA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Gallus gallus 15377 R-GGA-177923 https://reactome.org/PathwayBrowser/#/R-GGA-177923 Sustained activation of SRC kinase by SHP2 IEA Gallus gallus 15377 R-GGA-177924 https://reactome.org/PathwayBrowser/#/R-GGA-177924 Dephosphorylation of Gab1 by SHP2 IEA Gallus gallus 15377 R-GGA-177926 https://reactome.org/PathwayBrowser/#/R-GGA-177926 Dephosphorylation of PAG by SHP2 IEA Gallus gallus 15377 R-GGA-177935 https://reactome.org/PathwayBrowser/#/R-GGA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Gallus gallus 15377 R-GGA-1793182 https://reactome.org/PathwayBrowser/#/R-GGA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Gallus gallus 15377 R-GGA-1793186 https://reactome.org/PathwayBrowser/#/R-GGA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Gallus gallus 15377 R-GGA-1793207 https://reactome.org/PathwayBrowser/#/R-GGA-1793207 ARSB hydrolyses C4S/C6S chains IEA Gallus gallus 15377 R-GGA-1793209 https://reactome.org/PathwayBrowser/#/R-GGA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Gallus gallus 15377 R-GGA-1855154 https://reactome.org/PathwayBrowser/#/R-GGA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 15377 R-GGA-1855159 https://reactome.org/PathwayBrowser/#/R-GGA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Gallus gallus 15377 R-GGA-1855163 https://reactome.org/PathwayBrowser/#/R-GGA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Gallus gallus 15377 R-GGA-1855165 https://reactome.org/PathwayBrowser/#/R-GGA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 15377 R-GGA-1855166 https://reactome.org/PathwayBrowser/#/R-GGA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Gallus gallus 15377 R-GGA-1855171 https://reactome.org/PathwayBrowser/#/R-GGA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Gallus gallus 15377 R-GGA-1855174 https://reactome.org/PathwayBrowser/#/R-GGA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Gallus gallus 15377 R-GGA-1855177 https://reactome.org/PathwayBrowser/#/R-GGA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Gallus gallus 15377 R-GGA-1855180 https://reactome.org/PathwayBrowser/#/R-GGA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Gallus gallus 15377 R-GGA-1855198 https://reactome.org/PathwayBrowser/#/R-GGA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 15377 R-GGA-1855200 https://reactome.org/PathwayBrowser/#/R-GGA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Gallus gallus 15377 R-GGA-1855202 https://reactome.org/PathwayBrowser/#/R-GGA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Gallus gallus 15377 R-GGA-1855205 https://reactome.org/PathwayBrowser/#/R-GGA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Gallus gallus 15377 R-GGA-1855208 https://reactome.org/PathwayBrowser/#/R-GGA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Gallus gallus 15377 R-GGA-1855210 https://reactome.org/PathwayBrowser/#/R-GGA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 15377 R-GGA-1855211 https://reactome.org/PathwayBrowser/#/R-GGA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 15377 R-GGA-1855213 https://reactome.org/PathwayBrowser/#/R-GGA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Gallus gallus 15377 R-GGA-1855214 https://reactome.org/PathwayBrowser/#/R-GGA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Gallus gallus 15377 R-GGA-1855218 https://reactome.org/PathwayBrowser/#/R-GGA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Gallus gallus 15377 R-GGA-1855219 https://reactome.org/PathwayBrowser/#/R-GGA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 15377 R-GGA-1855221 https://reactome.org/PathwayBrowser/#/R-GGA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Gallus gallus 15377 R-GGA-1855222 https://reactome.org/PathwayBrowser/#/R-GGA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Gallus gallus 15377 R-GGA-1855225 https://reactome.org/PathwayBrowser/#/R-GGA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Gallus gallus 15377 R-GGA-1855232 https://reactome.org/PathwayBrowser/#/R-GGA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Gallus gallus 15377 R-GGA-1861788 https://reactome.org/PathwayBrowser/#/R-GGA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Gallus gallus 15377 R-GGA-187632 https://reactome.org/PathwayBrowser/#/R-GGA-187632 arginine + H2O => ornithine + urea TAS Gallus gallus 15377 R-GGA-188979 https://reactome.org/PathwayBrowser/#/R-GGA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Gallus gallus 15377 R-GGA-189053 https://reactome.org/PathwayBrowser/#/R-GGA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Gallus gallus 15377 R-GGA-189062 https://reactome.org/PathwayBrowser/#/R-GGA-189062 lactose + H2O => D-glucose + D-galactose IEA Gallus gallus 15377 R-GGA-189069 https://reactome.org/PathwayBrowser/#/R-GGA-189069 sucrose + H2O => glucose + fructose IEA Gallus gallus 15377 R-GGA-189102 https://reactome.org/PathwayBrowser/#/R-GGA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Gallus gallus 15377 R-GGA-189398 https://reactome.org/PathwayBrowser/#/R-GGA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Gallus gallus 15377 R-GGA-189406 https://reactome.org/PathwayBrowser/#/R-GGA-189406 4 PBGs bind to form HMB IEA Gallus gallus 15377 R-GGA-189421 https://reactome.org/PathwayBrowser/#/R-GGA-189421 CPO transforms COPRO3 to PPGEN9 IEA Gallus gallus 15377 R-GGA-189439 https://reactome.org/PathwayBrowser/#/R-GGA-189439 ALAD condenses 2 dALAs to form PBG IEA Gallus gallus 15377 R-GGA-189488 https://reactome.org/PathwayBrowser/#/R-GGA-189488 UROS transforms HMB to URO3 IEA Gallus gallus 15377 R-GGA-191101 https://reactome.org/PathwayBrowser/#/R-GGA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Gallus gallus 15377 R-GGA-191108 https://reactome.org/PathwayBrowser/#/R-GGA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus 15377 R-GGA-191114 https://reactome.org/PathwayBrowser/#/R-GGA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Gallus gallus 15377 R-GGA-191116 https://reactome.org/PathwayBrowser/#/R-GGA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Gallus gallus 15377 R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 15377 R-GGA-191323 https://reactome.org/PathwayBrowser/#/R-GGA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Gallus gallus 15377 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 15377 R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 15377 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 15377 R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 15377 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 15377 R-GGA-192178 https://reactome.org/PathwayBrowser/#/R-GGA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Gallus gallus 15377 R-GGA-192331 https://reactome.org/PathwayBrowser/#/R-GGA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Gallus gallus 15377 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 15377 R-GGA-192422 https://reactome.org/PathwayBrowser/#/R-GGA-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Gallus gallus 15377 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 15377 R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 15377 R-GGA-192434 https://reactome.org/PathwayBrowser/#/R-GGA-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Gallus gallus 15377 R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 15377 R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 15377 R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 15377 R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 15377 R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 15377 R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 15377 R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 15377 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 15377 R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 15377 R-GGA-193362 https://reactome.org/PathwayBrowser/#/R-GGA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Gallus gallus 15377 R-GGA-193385 https://reactome.org/PathwayBrowser/#/R-GGA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Gallus gallus 15377 R-GGA-193535 https://reactome.org/PathwayBrowser/#/R-GGA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Gallus gallus 15377 R-GGA-193711 https://reactome.org/PathwayBrowser/#/R-GGA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 15377 R-GGA-193727 https://reactome.org/PathwayBrowser/#/R-GGA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 15377 R-GGA-193743 https://reactome.org/PathwayBrowser/#/R-GGA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 15377 R-GGA-193766 https://reactome.org/PathwayBrowser/#/R-GGA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 15377 R-GGA-193964 https://reactome.org/PathwayBrowser/#/R-GGA-193964 CYP21A2 21-hydroxylates PROG IEA Gallus gallus 15377 R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 15377 R-GGA-194641 https://reactome.org/PathwayBrowser/#/R-GGA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15377 R-GGA-194669 https://reactome.org/PathwayBrowser/#/R-GGA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15377 R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 15377 R-GGA-195664 https://reactome.org/PathwayBrowser/#/R-GGA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Gallus gallus 15377 R-GGA-196950 https://reactome.org/PathwayBrowser/#/R-GGA-196950 2xTRAP hydrolyzes FMN to RIB IEA Gallus gallus 15377 R-GGA-197271 https://reactome.org/PathwayBrowser/#/R-GGA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Gallus gallus 15377 R-GGA-199425 https://reactome.org/PathwayBrowser/#/R-GGA-199425 PHLPP dephosphorylates S473 in AKT IEA Gallus gallus 15377 R-GGA-199456 https://reactome.org/PathwayBrowser/#/R-GGA-199456 PTEN dephosphorylates PIP3 IEA Gallus gallus 15377 R-GGA-2002466 https://reactome.org/PathwayBrowser/#/R-GGA-2002466 Formation of allysine by LOX IEA Gallus gallus 15377 R-GGA-200661 https://reactome.org/PathwayBrowser/#/R-GGA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Gallus gallus 15377 R-GGA-200740 https://reactome.org/PathwayBrowser/#/R-GGA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Gallus gallus 15377 R-GGA-201035 https://reactome.org/PathwayBrowser/#/R-GGA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Gallus gallus 15377 R-GGA-202214 https://reactome.org/PathwayBrowser/#/R-GGA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Gallus gallus 15377 R-GGA-2022368 https://reactome.org/PathwayBrowser/#/R-GGA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Gallus gallus 15377 R-GGA-202237 https://reactome.org/PathwayBrowser/#/R-GGA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Gallus gallus 15377 R-GGA-2022378 https://reactome.org/PathwayBrowser/#/R-GGA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Gallus gallus 15377 R-GGA-2022379 https://reactome.org/PathwayBrowser/#/R-GGA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Gallus gallus 15377 R-GGA-2022381 https://reactome.org/PathwayBrowser/#/R-GGA-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 15377 R-GGA-2022383 https://reactome.org/PathwayBrowser/#/R-GGA-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 15377 R-GGA-2022396 https://reactome.org/PathwayBrowser/#/R-GGA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Gallus gallus 15377 R-GGA-2022398 https://reactome.org/PathwayBrowser/#/R-GGA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Gallus gallus 15377 R-GGA-2022399 https://reactome.org/PathwayBrowser/#/R-GGA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Gallus gallus 15377 R-GGA-2022403 https://reactome.org/PathwayBrowser/#/R-GGA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Gallus gallus 15377 R-GGA-2022405 https://reactome.org/PathwayBrowser/#/R-GGA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 15377 R-GGA-2022411 https://reactome.org/PathwayBrowser/#/R-GGA-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 15377 R-GGA-2022412 https://reactome.org/PathwayBrowser/#/R-GGA-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Gallus gallus 15377 R-GGA-2022887 https://reactome.org/PathwayBrowser/#/R-GGA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Gallus gallus 15377 R-GGA-2023971 https://reactome.org/PathwayBrowser/#/R-GGA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 15377 R-GGA-2023973 https://reactome.org/PathwayBrowser/#/R-GGA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 15377 R-GGA-202407 https://reactome.org/PathwayBrowser/#/R-GGA-202407 PLC-gamma1 hydrolyses PIP2 IEA Gallus gallus 15377 R-GGA-2029468 https://reactome.org/PathwayBrowser/#/R-GGA-2029468 Conversion of PA into DAG by PAP-1 IEA Gallus gallus 15377 R-GGA-2029475 https://reactome.org/PathwayBrowser/#/R-GGA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Gallus gallus 15377 R-GGA-203797 https://reactome.org/PathwayBrowser/#/R-GGA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Gallus gallus 15377 R-GGA-204169 https://reactome.org/PathwayBrowser/#/R-GGA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Gallus gallus 15377 R-GGA-2046083 https://reactome.org/PathwayBrowser/#/R-GGA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Gallus gallus 15377 R-GGA-2046084 https://reactome.org/PathwayBrowser/#/R-GGA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Gallus gallus 15377 R-GGA-2046088 https://reactome.org/PathwayBrowser/#/R-GGA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Gallus gallus 15377 R-GGA-2046089 https://reactome.org/PathwayBrowser/#/R-GGA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Gallus gallus 15377 R-GGA-2046090 https://reactome.org/PathwayBrowser/#/R-GGA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 15377 R-GGA-2046092 https://reactome.org/PathwayBrowser/#/R-GGA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Gallus gallus 15377 R-GGA-2046094 https://reactome.org/PathwayBrowser/#/R-GGA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Gallus gallus 15377 R-GGA-2046095 https://reactome.org/PathwayBrowser/#/R-GGA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Gallus gallus 15377 R-GGA-2046096 https://reactome.org/PathwayBrowser/#/R-GGA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Gallus gallus 15377 R-GGA-2046097 https://reactome.org/PathwayBrowser/#/R-GGA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 15377 R-GGA-2046100 https://reactome.org/PathwayBrowser/#/R-GGA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Gallus gallus 15377 R-GGA-204662 https://reactome.org/PathwayBrowser/#/R-GGA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Gallus gallus 15377 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 15377 R-GGA-2065357 https://reactome.org/PathwayBrowser/#/R-GGA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Gallus gallus 15377 R-GGA-2066778 https://reactome.org/PathwayBrowser/#/R-GGA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Gallus gallus 15377 R-GGA-2066779 https://reactome.org/PathwayBrowser/#/R-GGA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Gallus gallus 15377 R-GGA-2090037 https://reactome.org/PathwayBrowser/#/R-GGA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Gallus gallus 15377 R-GGA-2090038 https://reactome.org/PathwayBrowser/#/R-GGA-2090038 NAGLU hydrolyses heparan chain(2) IEA Gallus gallus 15377 R-GGA-2090043 https://reactome.org/PathwayBrowser/#/R-GGA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Gallus gallus 15377 R-GGA-2090079 https://reactome.org/PathwayBrowser/#/R-GGA-2090079 GLB1 hydrolyses linker chain(2) IEA Gallus gallus 15377 R-GGA-209845 https://reactome.org/PathwayBrowser/#/R-GGA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Gallus gallus 15377 R-GGA-209891 https://reactome.org/PathwayBrowser/#/R-GGA-209891 Dopamine is oxidised to noradrenaline IEA Gallus gallus 15377 R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 15377 R-GGA-2105001 https://reactome.org/PathwayBrowser/#/R-GGA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Gallus gallus 15377 R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 15377 R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 15377 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 15377 R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus 15377 R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 15377 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 15377 R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 15377 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 15377 R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 15377 R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 15377 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 15377 R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 15377 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 15377 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 15377 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 15377 R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 15377 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 15377 R-GGA-2130725 https://reactome.org/PathwayBrowser/#/R-GGA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Gallus gallus 15377 R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 15377 R-GGA-2132047 https://reactome.org/PathwayBrowser/#/R-GGA-2132047 Spontaneous hydrolysis of an internal thioester bond in complement factor C3 TAS Gallus gallus 15377 R-GGA-2160874 https://reactome.org/PathwayBrowser/#/R-GGA-2160874 HYAL1 hydrolyses (HA)50 IEA Gallus gallus 15377 R-GGA-2161187 https://reactome.org/PathwayBrowser/#/R-GGA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Gallus gallus 15377 R-GGA-2161195 https://reactome.org/PathwayBrowser/#/R-GGA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Gallus gallus 15377 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Gallus gallus 15377 R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 15377 R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus 15377 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Gallus gallus 15377 R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 15377 R-GGA-2161951 https://reactome.org/PathwayBrowser/#/R-GGA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Gallus gallus 15377 R-GGA-2161959 https://reactome.org/PathwayBrowser/#/R-GGA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Gallus gallus 15377 R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Gallus gallus 15377 R-GGA-2161999 https://reactome.org/PathwayBrowser/#/R-GGA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Gallus gallus 15377 R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 15377 R-GGA-2162225 https://reactome.org/PathwayBrowser/#/R-GGA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Gallus gallus 15377 R-GGA-2162226 https://reactome.org/PathwayBrowser/#/R-GGA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Gallus gallus 15377 R-GGA-2162227 https://reactome.org/PathwayBrowser/#/R-GGA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Gallus gallus 15377 R-GGA-216723 https://reactome.org/PathwayBrowser/#/R-GGA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Gallus gallus 15377 R-GGA-216757 https://reactome.org/PathwayBrowser/#/R-GGA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Gallus gallus 15377 R-GGA-2187401 https://reactome.org/PathwayBrowser/#/R-GGA-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Gallus gallus 15377 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 15377 R-GGA-2393939 https://reactome.org/PathwayBrowser/#/R-GGA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 15377 R-GGA-2393954 https://reactome.org/PathwayBrowser/#/R-GGA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 15377 R-GGA-2395340 https://reactome.org/PathwayBrowser/#/R-GGA-2395340 Formation of hydroxyallysine by LOX IEA Gallus gallus 15377 R-GGA-2395818 https://reactome.org/PathwayBrowser/#/R-GGA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Gallus gallus 15377 R-GGA-2395849 https://reactome.org/PathwayBrowser/#/R-GGA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 15377 R-GGA-2395869 https://reactome.org/PathwayBrowser/#/R-GGA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 15377 R-GGA-2395872 https://reactome.org/PathwayBrowser/#/R-GGA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Gallus gallus 15377 R-GGA-2395876 https://reactome.org/PathwayBrowser/#/R-GGA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Gallus gallus 15377 R-GGA-2408551 https://reactome.org/PathwayBrowser/#/R-GGA-2408551 SeMet is converted to AdoSeMet by MAT IEA Gallus gallus 15377 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 15377 R-GGA-2454118 https://reactome.org/PathwayBrowser/#/R-GGA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Gallus gallus 15377 R-GGA-2465924 https://reactome.org/PathwayBrowser/#/R-GGA-2465924 OPN1LW binds 11cRAL IEA Gallus gallus 15377 R-GGA-2465974 https://reactome.org/PathwayBrowser/#/R-GGA-2465974 An REH hydrolyses 11cRE to 11cROL TAS Gallus gallus 15377 R-GGA-2466085 https://reactome.org/PathwayBrowser/#/R-GGA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Gallus gallus 15377 R-GGA-2509827 https://reactome.org/PathwayBrowser/#/R-GGA-2509827 ITPA hydrolyses ITP to IMP IEA Gallus gallus 15377 R-GGA-2509831 https://reactome.org/PathwayBrowser/#/R-GGA-2509831 ITPA hydrolyses XTP to XMP IEA Gallus gallus 15377 R-GGA-2509838 https://reactome.org/PathwayBrowser/#/R-GGA-2509838 ITPA hydrolyses dITP to dIMP IEA Gallus gallus 15377 R-GGA-2529015 https://reactome.org/PathwayBrowser/#/R-GGA-2529015 Dephosphorylation of CK2-modified condensin I IEA Gallus gallus 15377 R-GGA-2632521 https://reactome.org/PathwayBrowser/#/R-GGA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Gallus gallus 15377 R-GGA-265783 https://reactome.org/PathwayBrowser/#/R-GGA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Gallus gallus 15377 R-GGA-266012 https://reactome.org/PathwayBrowser/#/R-GGA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Gallus gallus 15377 R-GGA-266046 https://reactome.org/PathwayBrowser/#/R-GGA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Gallus gallus 15377 R-GGA-266051 https://reactome.org/PathwayBrowser/#/R-GGA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Gallus gallus 15377 R-GGA-266072 https://reactome.org/PathwayBrowser/#/R-GGA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Gallus gallus 15377 R-GGA-266082 https://reactome.org/PathwayBrowser/#/R-GGA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Gallus gallus 15377 R-GGA-2730847 https://reactome.org/PathwayBrowser/#/R-GGA-2730847 Hydrolysis of PIP2 by PLCG IEA Gallus gallus 15377 R-GGA-2730849 https://reactome.org/PathwayBrowser/#/R-GGA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Gallus gallus 15377 R-GGA-2855047 https://reactome.org/PathwayBrowser/#/R-GGA-2855047 Hydrolysis of internal thioester in C4b IEA Gallus gallus 15377 R-GGA-2859050 https://reactome.org/PathwayBrowser/#/R-GGA-2859050 Hydrolysis of C4b IEA Gallus gallus 15377 R-GGA-2995330 https://reactome.org/PathwayBrowser/#/R-GGA-2995330 COX10 transforms heme to heme O IEA Gallus gallus 15377 R-GGA-2995334 https://reactome.org/PathwayBrowser/#/R-GGA-2995334 COX15 transforms heme O to heme A IEA Gallus gallus 15377 R-GGA-2995388 https://reactome.org/PathwayBrowser/#/R-GGA-2995388 PP2A dephosphorylates BANF1 IEA Gallus gallus 15377 R-GGA-3002811 https://reactome.org/PathwayBrowser/#/R-GGA-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Gallus gallus 15377 R-GGA-3095901 https://reactome.org/PathwayBrowser/#/R-GGA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Gallus gallus 15377 R-GGA-3204311 https://reactome.org/PathwayBrowser/#/R-GGA-3204311 AOX1 oxidises PXL to PDXate IEA Gallus gallus 15377 R-GGA-3262512 https://reactome.org/PathwayBrowser/#/R-GGA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Gallus gallus 15377 R-GGA-3266566 https://reactome.org/PathwayBrowser/#/R-GGA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Gallus gallus 15377 R-GGA-3322995 https://reactome.org/PathwayBrowser/#/R-GGA-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Gallus gallus 15377 R-GGA-3341277 https://reactome.org/PathwayBrowser/#/R-GGA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Gallus gallus 15377 R-GGA-3341296 https://reactome.org/PathwayBrowser/#/R-GGA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Gallus gallus 15377 R-GGA-3341343 https://reactome.org/PathwayBrowser/#/R-GGA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Gallus gallus 15377 R-GGA-3341397 https://reactome.org/PathwayBrowser/#/R-GGA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Gallus gallus 15377 R-GGA-3371467 https://reactome.org/PathwayBrowser/#/R-GGA-3371467 SIRT1 deacetylates HSF1 IEA Gallus gallus 15377 R-GGA-350604 https://reactome.org/PathwayBrowser/#/R-GGA-350604 Agmatine + H2O <=> putrescine + urea IEA Gallus gallus 15377 R-GGA-350901 https://reactome.org/PathwayBrowser/#/R-GGA-350901 Iodide is organified IEA Gallus gallus 15377 R-GGA-352981 https://reactome.org/PathwayBrowser/#/R-GGA-352981 phosphoenolpyruvate + H2O <=> 2-phosphoglycerate TAS Gallus gallus 15377 R-GGA-353044 https://reactome.org/PathwayBrowser/#/R-GGA-353044 2-phosphoglycerate <=> phosphoenolpyruvate + H2O TAS Gallus gallus 15377 R-GGA-353058 https://reactome.org/PathwayBrowser/#/R-GGA-353058 glucose 6-phosphate + H2O => glucose + phosphate IEA Gallus gallus 15377 R-GGA-3640872 https://reactome.org/PathwayBrowser/#/R-GGA-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Gallus gallus 15377 R-GGA-372388 https://reactome.org/PathwayBrowser/#/R-GGA-372388 fructose 1,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate TAS Gallus gallus 15377 R-GGA-372425 https://reactome.org/PathwayBrowser/#/R-GGA-372425 fructose 2,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate TAS Gallus gallus 15377 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 15377 R-GGA-373006 https://reactome.org/PathwayBrowser/#/R-GGA-373006 acetyl-CoA + H2O + oxaloacetate => citrate + CoA TAS Gallus gallus 15377 R-GGA-373141 https://reactome.org/PathwayBrowser/#/R-GGA-373141 malate <=> fumarate + H2O TAS Gallus gallus 15377 R-GGA-373145 https://reactome.org/PathwayBrowser/#/R-GGA-373145 fumarate + H2O <=> malate IEA Gallus gallus 15377 R-GGA-374909 https://reactome.org/PathwayBrowser/#/R-GGA-374909 Catabolism of Noradrenaline IEA Gallus gallus 15377 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus 15377 R-GGA-377643 https://reactome.org/PathwayBrowser/#/R-GGA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Gallus gallus 15377 R-GGA-3777129 https://reactome.org/PathwayBrowser/#/R-GGA-3777129 HDAC3 containing complexes deacetylate histone IEA Gallus gallus 15377 R-GGA-3781011 https://reactome.org/PathwayBrowser/#/R-GGA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Gallus gallus 15377 R-GGA-3781018 https://reactome.org/PathwayBrowser/#/R-GGA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Gallus gallus 15377 R-GGA-3782637 https://reactome.org/PathwayBrowser/#/R-GGA-3782637 HDAC8 deacetylates histones IEA Gallus gallus 15377 R-GGA-3782655 https://reactome.org/PathwayBrowser/#/R-GGA-3782655 HDAC10 deacetylates histone IEA Gallus gallus 15377 R-GGA-379382 https://reactome.org/PathwayBrowser/#/R-GGA-379382 MAOA:FAD deaminates DA to DOPAC IEA Gallus gallus 15377 R-GGA-379395 https://reactome.org/PathwayBrowser/#/R-GGA-379395 MAOA:FAD deaminates 3MT to HVA IEA Gallus gallus 15377 R-GGA-380949 https://reactome.org/PathwayBrowser/#/R-GGA-380949 AMPK is dephosphorylated IEA Gallus gallus 15377 R-GGA-382560 https://reactome.org/PathwayBrowser/#/R-GGA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Gallus gallus 15377 R-GGA-382575 https://reactome.org/PathwayBrowser/#/R-GGA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Gallus gallus 15377 R-GGA-383190 https://reactome.org/PathwayBrowser/#/R-GGA-383190 HCO3- transport through ion channel IEA Gallus gallus 15377 R-GGA-389821 https://reactome.org/PathwayBrowser/#/R-GGA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Gallus gallus 15377 R-GGA-389862 https://reactome.org/PathwayBrowser/#/R-GGA-389862 Conversion of glyoxylate to oxalate IEA Gallus gallus 15377 R-GGA-389986 https://reactome.org/PathwayBrowser/#/R-GGA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Gallus gallus 15377 R-GGA-390252 https://reactome.org/PathwayBrowser/#/R-GGA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Gallus gallus 15377 R-GGA-390304 https://reactome.org/PathwayBrowser/#/R-GGA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Gallus gallus 15377 R-GGA-399998 https://reactome.org/PathwayBrowser/#/R-GGA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Gallus gallus 15377 R-GGA-4084976 https://reactome.org/PathwayBrowser/#/R-GGA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Gallus gallus 15377 R-GGA-4084989 https://reactome.org/PathwayBrowser/#/R-GGA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Gallus gallus 15377 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 15377 R-GGA-4085021 https://reactome.org/PathwayBrowser/#/R-GGA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Gallus gallus 15377 R-GGA-4085029 https://reactome.org/PathwayBrowser/#/R-GGA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 15377 R-GGA-4086392 https://reactome.org/PathwayBrowser/#/R-GGA-4086392 PDE6 hydrolyses cGMP to GMP IEA Gallus gallus 15377 R-GGA-4093339 https://reactome.org/PathwayBrowser/#/R-GGA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Gallus gallus 15377 R-GGA-416559 https://reactome.org/PathwayBrowser/#/R-GGA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Gallus gallus 15377 R-GGA-418553 https://reactome.org/PathwayBrowser/#/R-GGA-418553 cAMP degradation by Phosphodiesterases IEA Gallus gallus 15377 R-GGA-419144 https://reactome.org/PathwayBrowser/#/R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate TAS Gallus gallus 15377 R-GGA-419152 https://reactome.org/PathwayBrowser/#/R-GGA-419152 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate TAS Gallus gallus 15377 R-GGA-419253 https://reactome.org/PathwayBrowser/#/R-GGA-419253 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) <=> inosine 5'-monophosphate + H2O TAS Gallus gallus 15377 R-GGA-419440 https://reactome.org/PathwayBrowser/#/R-GGA-419440 L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate IEA Gallus gallus 15377 R-GGA-419465 https://reactome.org/PathwayBrowser/#/R-GGA-419465 N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O IEA Gallus gallus 15377 R-GGA-421158 https://reactome.org/PathwayBrowser/#/R-GGA-421158 xanthine + H2O + NAD+ => urate + NADH + H+ TAS Gallus gallus 15377 R-GGA-421161 https://reactome.org/PathwayBrowser/#/R-GGA-421161 hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ TAS Gallus gallus 15377 R-GGA-421179 https://reactome.org/PathwayBrowser/#/R-GGA-421179 inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate IEA Gallus gallus 15377 R-GGA-421218 https://reactome.org/PathwayBrowser/#/R-GGA-421218 xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate IEA Gallus gallus 15377 R-GGA-421222 https://reactome.org/PathwayBrowser/#/R-GGA-421222 inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ IEA Gallus gallus 15377 R-GGA-421439 https://reactome.org/PathwayBrowser/#/R-GGA-421439 4 porphobilinogen + H2O => hydroxymethylbilane + 4 NH3 IEA Gallus gallus 15377 R-GGA-421452 https://reactome.org/PathwayBrowser/#/R-GGA-421452 2 protoporphyrinogen IX + 3 O2 => 2 protoporphyrin IX + 6 H2O IEA Gallus gallus 15377 R-GGA-421471 https://reactome.org/PathwayBrowser/#/R-GGA-421471 hydroxymethylbilane => uroporphyrinogen I + H2O IEA Gallus gallus 15377 R-GGA-421472 https://reactome.org/PathwayBrowser/#/R-GGA-421472 2 delta-aminolevulinate => porphobilinogen + 2 H2O IEA Gallus gallus 15377 R-GGA-421482 https://reactome.org/PathwayBrowser/#/R-GGA-421482 hydroxymethylbilane => uroporphyrinogen III + H2O IEA Gallus gallus 15377 R-GGA-426043 https://reactome.org/PathwayBrowser/#/R-GGA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Gallus gallus 15377 R-GGA-428205 https://reactome.org/PathwayBrowser/#/R-GGA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Gallus gallus 15377 R-GGA-428231 https://reactome.org/PathwayBrowser/#/R-GGA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Gallus gallus 15377 R-GGA-428259 https://reactome.org/PathwayBrowser/#/R-GGA-428259 DEGS1 dehydrogenates dihydroceramide IEA Gallus gallus 15377 R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 15377 R-GGA-428262 https://reactome.org/PathwayBrowser/#/R-GGA-428262 ACER3 hydrolyzes phytoceramide IEA Gallus gallus 15377 R-GGA-428664 https://reactome.org/PathwayBrowser/#/R-GGA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Gallus gallus 15377 R-GGA-428690 https://reactome.org/PathwayBrowser/#/R-GGA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Gallus gallus 15377 R-GGA-428696 https://reactome.org/PathwayBrowser/#/R-GGA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Gallus gallus 15377 R-GGA-429157 https://reactome.org/PathwayBrowser/#/R-GGA-429157 ABCC4 accumulation of dense granule contents IEA Gallus gallus 15377 R-GGA-429860 https://reactome.org/PathwayBrowser/#/R-GGA-429860 DCP1-DCP2 complex decaps mRNA IEA Gallus gallus 15377 R-GGA-429955 https://reactome.org/PathwayBrowser/#/R-GGA-429955 CCR4-NOT complex deadenylates mRNA IEA Gallus gallus 15377 R-GGA-429961 https://reactome.org/PathwayBrowser/#/R-GGA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Gallus gallus 15377 R-GGA-429992 https://reactome.org/PathwayBrowser/#/R-GGA-429992 PARN deadenylates mRNA IEA Gallus gallus 15377 R-GGA-430021 https://reactome.org/PathwayBrowser/#/R-GGA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Gallus gallus 15377 R-GGA-430028 https://reactome.org/PathwayBrowser/#/R-GGA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Gallus gallus 15377 R-GGA-432010 https://reactome.org/PathwayBrowser/#/R-GGA-432010 Aquaporin-1 passively transports water into cell IEA Gallus gallus 15377 R-GGA-432054 https://reactome.org/PathwayBrowser/#/R-GGA-432054 Aquaporin-1 passively transports water out of cell IEA Gallus gallus 15377 R-GGA-432065 https://reactome.org/PathwayBrowser/#/R-GGA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Gallus gallus 15377 R-GGA-432067 https://reactome.org/PathwayBrowser/#/R-GGA-432067 Aquaporin-4 passively transports water out of cell IEA Gallus gallus 15377 R-GGA-433578 https://reactome.org/PathwayBrowser/#/R-GGA-433578 phytoceramide + H2O => stearate + phytosphingosine IEA Gallus gallus 15377 R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 15377 R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 15377 R-GGA-433608 https://reactome.org/PathwayBrowser/#/R-GGA-433608 ceramide + H2O => stearate + sphingosine [endoplasmic reticulum] IEA Gallus gallus 15377 R-GGA-445714 https://reactome.org/PathwayBrowser/#/R-GGA-445714 Aquaporin-3 passively transports water out of cell IEA Gallus gallus 15377 R-GGA-446200 https://reactome.org/PathwayBrowser/#/R-GGA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Gallus gallus 15377 R-GGA-449937 https://reactome.org/PathwayBrowser/#/R-GGA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Gallus gallus 15377 R-GGA-452036 https://reactome.org/PathwayBrowser/#/R-GGA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Gallus gallus 15377 R-GGA-4551451 https://reactome.org/PathwayBrowser/#/R-GGA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Gallus gallus 15377 R-GGA-4641236 https://reactome.org/PathwayBrowser/#/R-GGA-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Gallus gallus 15377 R-GGA-504054 https://reactome.org/PathwayBrowser/#/R-GGA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Gallus gallus 15377 R-GGA-507868 https://reactome.org/PathwayBrowser/#/R-GGA-507868 Aquaporins passively transport water into cells IEA Gallus gallus 15377 R-GGA-507870 https://reactome.org/PathwayBrowser/#/R-GGA-507870 Aquaporins passively transport water out of cells IEA Gallus gallus 15377 R-GGA-508308 https://reactome.org/PathwayBrowser/#/R-GGA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Gallus gallus 15377 R-GGA-5221130 https://reactome.org/PathwayBrowser/#/R-GGA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Gallus gallus 15377 R-GGA-5223313 https://reactome.org/PathwayBrowser/#/R-GGA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Gallus gallus 15377 R-GGA-5223317 https://reactome.org/PathwayBrowser/#/R-GGA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Gallus gallus 15377 R-GGA-5251989 https://reactome.org/PathwayBrowser/#/R-GGA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Gallus gallus 15377 R-GGA-5263614 https://reactome.org/PathwayBrowser/#/R-GGA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Gallus gallus 15377 R-GGA-5263616 https://reactome.org/PathwayBrowser/#/R-GGA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Gallus gallus 15377 R-GGA-5362459 https://reactome.org/PathwayBrowser/#/R-GGA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Gallus gallus 15377 R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus 15377 R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 15377 R-GGA-5423664 https://reactome.org/PathwayBrowser/#/R-GGA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Gallus gallus 15377 R-GGA-5423672 https://reactome.org/PathwayBrowser/#/R-GGA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Gallus gallus 15377 R-GGA-5423678 https://reactome.org/PathwayBrowser/#/R-GGA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Gallus gallus 15377 R-GGA-5433072 https://reactome.org/PathwayBrowser/#/R-GGA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Gallus gallus 15377 R-GGA-5433074 https://reactome.org/PathwayBrowser/#/R-GGA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Gallus gallus 15377 R-GGA-548843 https://reactome.org/PathwayBrowser/#/R-GGA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Gallus gallus 15377 R-GGA-5603114 https://reactome.org/PathwayBrowser/#/R-GGA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Gallus gallus 15377 R-GGA-5607735 https://reactome.org/PathwayBrowser/#/R-GGA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Gallus gallus 15377 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 15377 R-GGA-5623513 https://reactome.org/PathwayBrowser/#/R-GGA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Gallus gallus 15377 R-GGA-5628905 https://reactome.org/PathwayBrowser/#/R-GGA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Gallus gallus 15377 R-GGA-5631885 https://reactome.org/PathwayBrowser/#/R-GGA-5631885 PRDX1 overoxidizes IEA Gallus gallus 15377 R-GGA-5651828 https://reactome.org/PathwayBrowser/#/R-GGA-5651828 PARG dePARylates PARP1,PARP2 IEA Gallus gallus 15377 R-GGA-5653770 https://reactome.org/PathwayBrowser/#/R-GGA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Gallus gallus 15377 R-GGA-5659861 https://reactome.org/PathwayBrowser/#/R-GGA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus 15377 R-GGA-5662692 https://reactome.org/PathwayBrowser/#/R-GGA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Gallus gallus 15377 R-GGA-5675373 https://reactome.org/PathwayBrowser/#/R-GGA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Gallus gallus 15377 R-GGA-5675376 https://reactome.org/PathwayBrowser/#/R-GGA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Gallus gallus 15377 R-GGA-5676637 https://reactome.org/PathwayBrowser/#/R-GGA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Gallus gallus 15377 R-GGA-5678327 https://reactome.org/PathwayBrowser/#/R-GGA-5678327 MIOX oxidises Ins to GlcA IEA Gallus gallus 15377 R-GGA-5678706 https://reactome.org/PathwayBrowser/#/R-GGA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Gallus gallus 15377 R-GGA-5678863 https://reactome.org/PathwayBrowser/#/R-GGA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Gallus gallus 15377 R-GGA-5679041 https://reactome.org/PathwayBrowser/#/R-GGA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Gallus gallus 15377 R-GGA-5682285 https://reactome.org/PathwayBrowser/#/R-GGA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Gallus gallus 15377 R-GGA-5683714 https://reactome.org/PathwayBrowser/#/R-GGA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Gallus gallus 15377 R-GGA-5683967 https://reactome.org/PathwayBrowser/#/R-GGA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Gallus gallus 15377 R-GGA-5684864 https://reactome.org/PathwayBrowser/#/R-GGA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Gallus gallus 15377 R-GGA-5685902 https://reactome.org/PathwayBrowser/#/R-GGA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Gallus gallus 15377 R-GGA-5685994 https://reactome.org/PathwayBrowser/#/R-GGA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Gallus gallus 15377 R-GGA-5687464 https://reactome.org/PathwayBrowser/#/R-GGA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Gallus gallus 15377 R-GGA-5687664 https://reactome.org/PathwayBrowser/#/R-GGA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Gallus gallus 15377 R-GGA-5687758 https://reactome.org/PathwayBrowser/#/R-GGA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Gallus gallus 15377 R-GGA-5688797 https://reactome.org/PathwayBrowser/#/R-GGA-5688797 ATXN3 family cleave Ub chains IEA Gallus gallus 15377 R-GGA-5688837 https://reactome.org/PathwayBrowser/#/R-GGA-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Gallus gallus 15377 R-GGA-5689000 https://reactome.org/PathwayBrowser/#/R-GGA-5689000 AADAC deacetylates PHEN IEA Gallus gallus 15377 R-GGA-5689950 https://reactome.org/PathwayBrowser/#/R-GGA-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Gallus gallus 15377 R-GGA-5690042 https://reactome.org/PathwayBrowser/#/R-GGA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 15377 R-GGA-5690043 https://reactome.org/PathwayBrowser/#/R-GGA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 15377 R-GGA-5690066 https://reactome.org/PathwayBrowser/#/R-GGA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 15377 R-GGA-5690152 https://reactome.org/PathwayBrowser/#/R-GGA-5690152 USP5 cleaves polyubiquitin IEA Gallus gallus 15377 R-GGA-5690157 https://reactome.org/PathwayBrowser/#/R-GGA-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Gallus gallus 15377 R-GGA-5690196 https://reactome.org/PathwayBrowser/#/R-GGA-5690196 USP8 deubiquitinates RNF128 IEA Gallus gallus 15377 R-GGA-5690319 https://reactome.org/PathwayBrowser/#/R-GGA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Gallus gallus 15377 R-GGA-5690517 https://reactome.org/PathwayBrowser/#/R-GGA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Gallus gallus 15377 R-GGA-5690565 https://reactome.org/PathwayBrowser/#/R-GGA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15377 R-GGA-5690790 https://reactome.org/PathwayBrowser/#/R-GGA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Gallus gallus 15377 R-GGA-5690808 https://reactome.org/PathwayBrowser/#/R-GGA-5690808 UCHL3, SENP8 cleave NEDD8 IEA Gallus gallus 15377 R-GGA-5690856 https://reactome.org/PathwayBrowser/#/R-GGA-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Gallus gallus 15377 R-GGA-5690870 https://reactome.org/PathwayBrowser/#/R-GGA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Gallus gallus 15377 R-GGA-5691381 https://reactome.org/PathwayBrowser/#/R-GGA-5691381 MYSM1 deubiquitinates Histone H2A IEA Gallus gallus 15377 R-GGA-5691411 https://reactome.org/PathwayBrowser/#/R-GGA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Gallus gallus 15377 R-GGA-5691439 https://reactome.org/PathwayBrowser/#/R-GGA-5691439 BRISC complex deubiquitinates NLRP3 IEA Gallus gallus 15377 R-GGA-5691507 https://reactome.org/PathwayBrowser/#/R-GGA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Gallus gallus 15377 R-GGA-5691512 https://reactome.org/PathwayBrowser/#/R-GGA-5691512 APEH hydrolyses NAc-Ser-protein IEA Gallus gallus 15377 R-GGA-5692261 https://reactome.org/PathwayBrowser/#/R-GGA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Gallus gallus 15377 R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus 15377 R-GGA-5692462 https://reactome.org/PathwayBrowser/#/R-GGA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Gallus gallus 15377 R-GGA-5692480 https://reactome.org/PathwayBrowser/#/R-GGA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Gallus gallus 15377 R-GGA-5692754 https://reactome.org/PathwayBrowser/#/R-GGA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Gallus gallus 15377 R-GGA-5693153 https://reactome.org/PathwayBrowser/#/R-GGA-5693153 PPM1K dephosphorylates p-BCKDH IEA Gallus gallus 15377 R-GGA-5693346 https://reactome.org/PathwayBrowser/#/R-GGA-5693346 CECRI deaminates Ade-Rib to Ino IEA Gallus gallus 15377 R-GGA-5693373 https://reactome.org/PathwayBrowser/#/R-GGA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Gallus gallus 15377 R-GGA-5693608 https://reactome.org/PathwayBrowser/#/R-GGA-5693608 Initial resection of double-strand break ends IEA Gallus gallus 15377 R-GGA-5693691 https://reactome.org/PathwayBrowser/#/R-GGA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Gallus gallus 15377 R-GGA-5693724 https://reactome.org/PathwayBrowser/#/R-GGA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Gallus gallus 15377 R-GGA-5693742 https://reactome.org/PathwayBrowser/#/R-GGA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Gallus gallus 15377 R-GGA-5693751 https://reactome.org/PathwayBrowser/#/R-GGA-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Gallus gallus 15377 R-GGA-5693761 https://reactome.org/PathwayBrowser/#/R-GGA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Gallus gallus 15377 R-GGA-5693807 https://reactome.org/PathwayBrowser/#/R-GGA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Gallus gallus 15377 R-GGA-5694077 https://reactome.org/PathwayBrowser/#/R-GGA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Gallus gallus 15377 R-GGA-5694109 https://reactome.org/PathwayBrowser/#/R-GGA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Gallus gallus 15377 R-GGA-5694126 https://reactome.org/PathwayBrowser/#/R-GGA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Gallus gallus 15377 R-GGA-5694421 https://reactome.org/PathwayBrowser/#/R-GGA-5694421 PP6 dephosphorylates SEC24 IEA Gallus gallus 15377 R-GGA-5694462 https://reactome.org/PathwayBrowser/#/R-GGA-5694462 ABHD6,12 hydrolyse 3AG IEA Gallus gallus 15377 R-GGA-5694485 https://reactome.org/PathwayBrowser/#/R-GGA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Gallus gallus 15377 R-GGA-5694563 https://reactome.org/PathwayBrowser/#/R-GGA-5694563 ABHD10 hydrolyses MPAG IEA Gallus gallus 15377 R-GGA-5695964 https://reactome.org/PathwayBrowser/#/R-GGA-5695964 ABHD14B hydrolyses PNPB IEA Gallus gallus 15377 R-GGA-5696049 https://reactome.org/PathwayBrowser/#/R-GGA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 15377 R-GGA-5696080 https://reactome.org/PathwayBrowser/#/R-GGA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Gallus gallus 15377 R-GGA-5696101 https://reactome.org/PathwayBrowser/#/R-GGA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Gallus gallus 15377 R-GGA-5696119 https://reactome.org/PathwayBrowser/#/R-GGA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Gallus gallus 15377 R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 15377 R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 15377 R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 15377 R-GGA-5696197 https://reactome.org/PathwayBrowser/#/R-GGA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Gallus gallus 15377 R-GGA-5696230 https://reactome.org/PathwayBrowser/#/R-GGA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Gallus gallus 15377 R-GGA-5696365 https://reactome.org/PathwayBrowser/#/R-GGA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Gallus gallus 15377 R-GGA-5696408 https://reactome.org/PathwayBrowser/#/R-GGA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Gallus gallus 15377 R-GGA-5696415 https://reactome.org/PathwayBrowser/#/R-GGA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Gallus gallus 15377 R-GGA-5696534 https://reactome.org/PathwayBrowser/#/R-GGA-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Gallus gallus 15377 R-GGA-5696605 https://reactome.org/PathwayBrowser/#/R-GGA-5696605 USP12, USP26 deubiquitinate AR IEA Gallus gallus 15377 R-GGA-5696627 https://reactome.org/PathwayBrowser/#/R-GGA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Gallus gallus 15377 R-GGA-5696872 https://reactome.org/PathwayBrowser/#/R-GGA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Gallus gallus 15377 R-GGA-5696914 https://reactome.org/PathwayBrowser/#/R-GGA-5696914 USP28 deubiquitinates CLSPN and MYC IEA Gallus gallus 15377 R-GGA-5696945 https://reactome.org/PathwayBrowser/#/R-GGA-5696945 USP33 deubiquitinates CCP110,ARRB IEA Gallus gallus 15377 R-GGA-5696958 https://reactome.org/PathwayBrowser/#/R-GGA-5696958 USP44 deubiquitinates CDC20 IEA Gallus gallus 15377 R-GGA-5696960 https://reactome.org/PathwayBrowser/#/R-GGA-5696960 USP49 deubiquitinates H2B IEA Gallus gallus 15377 R-GGA-5696968 https://reactome.org/PathwayBrowser/#/R-GGA-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Gallus gallus 15377 R-GGA-5696997 https://reactome.org/PathwayBrowser/#/R-GGA-5696997 USP24 deubiquitinates DDB2 IEA Gallus gallus 15377 R-GGA-5697009 https://reactome.org/PathwayBrowser/#/R-GGA-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Gallus gallus 15377 R-GGA-6781764 https://reactome.org/PathwayBrowser/#/R-GGA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Gallus gallus 15377 R-GGA-6781779 https://reactome.org/PathwayBrowser/#/R-GGA-6781779 USP13 deubiquitinates BECN1,USP10 IEA Gallus gallus 15377 R-GGA-6781814 https://reactome.org/PathwayBrowser/#/R-GGA-6781814 USP19 deubiquitinates RNF123 IEA Gallus gallus 15377 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus 15377 R-GGA-6782106 https://reactome.org/PathwayBrowser/#/R-GGA-6782106 USP10 deubiquitinates SNX3, CFTR IEA Gallus gallus 15377 R-GGA-6782628 https://reactome.org/PathwayBrowser/#/R-GGA-6782628 USP8 deubiquitinates STAM2:HGS IEA Gallus gallus 15377 R-GGA-6783221 https://reactome.org/PathwayBrowser/#/R-GGA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Gallus gallus 15377 R-GGA-6784959 https://reactome.org/PathwayBrowser/#/R-GGA-6784959 BPHL hydrolyses VACV to ACV IEA Gallus gallus 15377 R-GGA-6786190 https://reactome.org/PathwayBrowser/#/R-GGA-6786190 CMBL hydrolyses OM to OLMS IEA Gallus gallus 15377 R-GGA-6786239 https://reactome.org/PathwayBrowser/#/R-GGA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Gallus gallus 15377 R-GGA-6786421 https://reactome.org/PathwayBrowser/#/R-GGA-6786421 CHIA hydrolyses chitin IEA Gallus gallus 15377 R-GGA-6786650 https://reactome.org/PathwayBrowser/#/R-GGA-6786650 DDHD1,2 hydrolyse PA IEA Gallus gallus 15377 R-GGA-6787632 https://reactome.org/PathwayBrowser/#/R-GGA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Gallus gallus 15377 R-GGA-6788295 https://reactome.org/PathwayBrowser/#/R-GGA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Gallus gallus 15377 R-GGA-6788912 https://reactome.org/PathwayBrowser/#/R-GGA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Gallus gallus 15377 R-GGA-6789031 https://reactome.org/PathwayBrowser/#/R-GGA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 15377 R-GGA-6789126 https://reactome.org/PathwayBrowser/#/R-GGA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 15377 R-GGA-6789310 https://reactome.org/PathwayBrowser/#/R-GGA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Gallus gallus 15377 R-GGA-6792445 https://reactome.org/PathwayBrowser/#/R-GGA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Gallus gallus 15377 R-GGA-6797627 https://reactome.org/PathwayBrowser/#/R-GGA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Gallus gallus 15377 R-GGA-6797630 https://reactome.org/PathwayBrowser/#/R-GGA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Gallus gallus 15377 R-GGA-6797653 https://reactome.org/PathwayBrowser/#/R-GGA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Gallus gallus 15377 R-GGA-6797913 https://reactome.org/PathwayBrowser/#/R-GGA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Gallus gallus 15377 R-GGA-6797955 https://reactome.org/PathwayBrowser/#/R-GGA-6797955 ALDH7A1 oxidises BETALD to BET IEA Gallus gallus 15377 R-GGA-6799545 https://reactome.org/PathwayBrowser/#/R-GGA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Gallus gallus 15377 R-GGA-6799581 https://reactome.org/PathwayBrowser/#/R-GGA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Gallus gallus 15377 R-GGA-6799604 https://reactome.org/PathwayBrowser/#/R-GGA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Gallus gallus 15377 R-GGA-6799977 https://reactome.org/PathwayBrowser/#/R-GGA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Gallus gallus 15377 R-GGA-6800299 https://reactome.org/PathwayBrowser/#/R-GGA-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Gallus gallus 15377 R-GGA-6801462 https://reactome.org/PathwayBrowser/#/R-GGA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Gallus gallus 15377 R-GGA-6803545 https://reactome.org/PathwayBrowser/#/R-GGA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Gallus gallus 15377 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 15377 R-GGA-6803789 https://reactome.org/PathwayBrowser/#/R-GGA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Gallus gallus 15377 R-GGA-6807008 https://reactome.org/PathwayBrowser/#/R-GGA-6807008 PTPRJ dephosphorylates MET IEA Gallus gallus 15377 R-GGA-6807027 https://reactome.org/PathwayBrowser/#/R-GGA-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Gallus gallus 15377 R-GGA-6807053 https://reactome.org/PathwayBrowser/#/R-GGA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Gallus gallus 15377 R-GGA-6807118 https://reactome.org/PathwayBrowser/#/R-GGA-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Gallus gallus 15377 R-GGA-6807206 https://reactome.org/PathwayBrowser/#/R-GGA-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Gallus gallus 15377 R-GGA-6808464 https://reactome.org/PathwayBrowser/#/R-GGA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Gallus gallus 15377 R-GGA-6808487 https://reactome.org/PathwayBrowser/#/R-GGA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Gallus gallus 15377 R-GGA-6809263 https://reactome.org/PathwayBrowser/#/R-GGA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Gallus gallus 15377 R-GGA-6809287 https://reactome.org/PathwayBrowser/#/R-GGA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Gallus gallus 15377 R-GGA-6809320 https://reactome.org/PathwayBrowser/#/R-GGA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Gallus gallus 15377 R-GGA-6809325 https://reactome.org/PathwayBrowser/#/R-GGA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Gallus gallus 15377 R-GGA-6809720 https://reactome.org/PathwayBrowser/#/R-GGA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Gallus gallus 15377 R-GGA-6809777 https://reactome.org/PathwayBrowser/#/R-GGA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Gallus gallus 15377 R-GGA-6809778 https://reactome.org/PathwayBrowser/#/R-GGA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Gallus gallus 15377 R-GGA-6810076 https://reactome.org/PathwayBrowser/#/R-GGA-6810076 DDO oxidizes D-Asp to OA IEA Gallus gallus 15377 R-GGA-6810464 https://reactome.org/PathwayBrowser/#/R-GGA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Gallus gallus 15377 R-GGA-6810472 https://reactome.org/PathwayBrowser/#/R-GGA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Gallus gallus 15377 R-GGA-6810474 https://reactome.org/PathwayBrowser/#/R-GGA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Gallus gallus 15377 R-GGA-6813720 https://reactome.org/PathwayBrowser/#/R-GGA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Gallus gallus 15377 R-GGA-6813740 https://reactome.org/PathwayBrowser/#/R-GGA-6813740 GDE1 hydrolyzes GroPIns IEA Gallus gallus 15377 R-GGA-6813749 https://reactome.org/PathwayBrowser/#/R-GGA-6813749 ALDH1A1 oxidises GA to DGA IEA Gallus gallus 15377 R-GGA-6814254 https://reactome.org/PathwayBrowser/#/R-GGA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Gallus gallus 15377 R-GGA-6814797 https://reactome.org/PathwayBrowser/#/R-GGA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Gallus gallus 15377 R-GGA-69199 https://reactome.org/PathwayBrowser/#/R-GGA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Gallus gallus 15377 R-GGA-70262 https://reactome.org/PathwayBrowser/#/R-GGA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Gallus gallus 15377 R-GGA-70479 https://reactome.org/PathwayBrowser/#/R-GGA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Gallus gallus 15377 R-GGA-70494 https://reactome.org/PathwayBrowser/#/R-GGA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Gallus gallus 15377 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Gallus gallus 15377 R-GGA-70599 https://reactome.org/PathwayBrowser/#/R-GGA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Gallus gallus 15377 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Gallus gallus 15377 R-GGA-70609 https://reactome.org/PathwayBrowser/#/R-GGA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Gallus gallus 15377 R-GGA-70679 https://reactome.org/PathwayBrowser/#/R-GGA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Gallus gallus 15377 R-GGA-70785 https://reactome.org/PathwayBrowser/#/R-GGA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Gallus gallus 15377 R-GGA-70881 https://reactome.org/PathwayBrowser/#/R-GGA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Gallus gallus 15377 R-GGA-70903 https://reactome.org/PathwayBrowser/#/R-GGA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Gallus gallus 15377 R-GGA-70906 https://reactome.org/PathwayBrowser/#/R-GGA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Gallus gallus 15377 R-GGA-70938 https://reactome.org/PathwayBrowser/#/R-GGA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Gallus gallus 15377 R-GGA-70940 https://reactome.org/PathwayBrowser/#/R-GGA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Gallus gallus 15377 R-GGA-70941 https://reactome.org/PathwayBrowser/#/R-GGA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Gallus gallus 15377 R-GGA-70975 https://reactome.org/PathwayBrowser/#/R-GGA-70975 CS acetylates OA to citrate IEA Gallus gallus 15377 R-GGA-70982 https://reactome.org/PathwayBrowser/#/R-GGA-70982 FH tetramer hydrates fumarate to L-malate IEA Gallus gallus 15377 R-GGA-71146 https://reactome.org/PathwayBrowser/#/R-GGA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Gallus gallus 15377 R-GGA-71181 https://reactome.org/PathwayBrowser/#/R-GGA-71181 FAH cleaves 4FAA IEA Gallus gallus 15377 R-GGA-71200 https://reactome.org/PathwayBrowser/#/R-GGA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Gallus gallus 15377 R-GGA-71217 https://reactome.org/PathwayBrowser/#/R-GGA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Gallus gallus 15377 R-GGA-71260 https://reactome.org/PathwayBrowser/#/R-GGA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Gallus gallus 15377 R-GGA-71296 https://reactome.org/PathwayBrowser/#/R-GGA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Gallus gallus 15377 R-GGA-71660 https://reactome.org/PathwayBrowser/#/R-GGA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Gallus gallus 15377 R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 15377 R-GGA-71723 https://reactome.org/PathwayBrowser/#/R-GGA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Gallus gallus 15377 R-GGA-71732 https://reactome.org/PathwayBrowser/#/R-GGA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Gallus gallus 15377 R-GGA-71825 https://reactome.org/PathwayBrowser/#/R-GGA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Gallus gallus 15377 R-GGA-73589 https://reactome.org/PathwayBrowser/#/R-GGA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Gallus gallus 15377 R-GGA-73591 https://reactome.org/PathwayBrowser/#/R-GGA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Gallus gallus 15377 R-GGA-73596 https://reactome.org/PathwayBrowser/#/R-GGA-73596 dCMP + H2O => dUMP + NH4+ IEA Gallus gallus 15377 R-GGA-73608 https://reactome.org/PathwayBrowser/#/R-GGA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Gallus gallus 15377 R-GGA-73618 https://reactome.org/PathwayBrowser/#/R-GGA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Gallus gallus 15377 R-GGA-73620 https://reactome.org/PathwayBrowser/#/R-GGA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Gallus gallus 15377 R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus 15377 R-GGA-73666 https://reactome.org/PathwayBrowser/#/R-GGA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Gallus gallus 15377 R-GGA-73792 https://reactome.org/PathwayBrowser/#/R-GGA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Gallus gallus 15377 R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus 15377 R-GGA-73797 https://reactome.org/PathwayBrowser/#/R-GGA-73797 FAICAR => IMP + H2O IEA Gallus gallus 15377 R-GGA-73815 https://reactome.org/PathwayBrowser/#/R-GGA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Gallus gallus 15377 R-GGA-74241 https://reactome.org/PathwayBrowser/#/R-GGA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Gallus gallus 15377 R-GGA-74247 https://reactome.org/PathwayBrowser/#/R-GGA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Gallus gallus 15377 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 15377 R-GGA-74255 https://reactome.org/PathwayBrowser/#/R-GGA-74255 Guanine + H2O => Xanthine + NH4+ IEA Gallus gallus 15377 R-GGA-74258 https://reactome.org/PathwayBrowser/#/R-GGA-74258 XDH oxidizes xanthine to form urate IEA Gallus gallus 15377 R-GGA-74733 https://reactome.org/PathwayBrowser/#/R-GGA-74733 Insulin receptor de-phosphorylation IEA Gallus gallus 15377 R-GGA-74948 https://reactome.org/PathwayBrowser/#/R-GGA-74948 PP2A dephosphorylates p-RHO to RHO IEA Gallus gallus 15377 R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Gallus gallus 15377 R-GGA-75899 https://reactome.org/PathwayBrowser/#/R-GGA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Gallus gallus 15377 R-GGA-76031 https://reactome.org/PathwayBrowser/#/R-GGA-76031 2 H2O2 => O2 + 2 H2O IEA Gallus gallus 15377 R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 15377 R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 15377 R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 15377 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 15377 R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 15377 R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 15377 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 15377 R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 15377 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 15377 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 15377 R-GGA-76590 https://reactome.org/PathwayBrowser/#/R-GGA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Gallus gallus 15377 R-GGA-77277 https://reactome.org/PathwayBrowser/#/R-GGA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Gallus gallus 15377 R-GGA-77301 https://reactome.org/PathwayBrowser/#/R-GGA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Gallus gallus 15377 R-GGA-77614 https://reactome.org/PathwayBrowser/#/R-GGA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Gallus gallus 15377 R-GGA-8847579 https://reactome.org/PathwayBrowser/#/R-GGA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15377 R-GGA-8848053 https://reactome.org/PathwayBrowser/#/R-GGA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Gallus gallus 15377 R-GGA-8848215 https://reactome.org/PathwayBrowser/#/R-GGA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Gallus gallus 15377 R-GGA-8848338 https://reactome.org/PathwayBrowser/#/R-GGA-8848338 PNPLA4 hydrolyzes TAG IEA Gallus gallus 15377 R-GGA-8848339 https://reactome.org/PathwayBrowser/#/R-GGA-8848339 PNPLA5 hydrolyzes TAG IEA Gallus gallus 15377 R-GGA-8848355 https://reactome.org/PathwayBrowser/#/R-GGA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Gallus gallus 15377 R-GGA-8848484 https://reactome.org/PathwayBrowser/#/R-GGA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Gallus gallus 15377 R-GGA-8849969 https://reactome.org/PathwayBrowser/#/R-GGA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Gallus gallus 15377 R-GGA-8850594 https://reactome.org/PathwayBrowser/#/R-GGA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Gallus gallus 15377 R-GGA-8850846 https://reactome.org/PathwayBrowser/#/R-GGA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-GGA-8850854 https://reactome.org/PathwayBrowser/#/R-GGA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-GGA-8851110 https://reactome.org/PathwayBrowser/#/R-GGA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-GGA-8851129 https://reactome.org/PathwayBrowser/#/R-GGA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-GGA-8852200 https://reactome.org/PathwayBrowser/#/R-GGA-8852200 Inactivation of LCK by PTPN22 IEA Gallus gallus 15377 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 15377 R-GGA-8854173 https://reactome.org/PathwayBrowser/#/R-GGA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Gallus gallus 15377 R-GGA-8854255 https://reactome.org/PathwayBrowser/#/R-GGA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 15377 R-GGA-8854329 https://reactome.org/PathwayBrowser/#/R-GGA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 15377 R-GGA-8854604 https://reactome.org/PathwayBrowser/#/R-GGA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Gallus gallus 15377 R-GGA-8854612 https://reactome.org/PathwayBrowser/#/R-GGA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Gallus gallus 15377 R-GGA-8855381 https://reactome.org/PathwayBrowser/#/R-GGA-8855381 PTPN22 dephosphorylates ZAP70 IEA Gallus gallus 15377 R-GGA-8855490 https://reactome.org/PathwayBrowser/#/R-GGA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Gallus gallus 15377 R-GGA-8855825 https://reactome.org/PathwayBrowser/#/R-GGA-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Gallus gallus 15377 R-GGA-8862184 https://reactome.org/PathwayBrowser/#/R-GGA-8862184 USP48 cleaves polyubiquitin IEA Gallus gallus 15377 R-GGA-8862320 https://reactome.org/PathwayBrowser/#/R-GGA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Gallus gallus 15377 R-GGA-8863804 https://reactome.org/PathwayBrowser/#/R-GGA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Gallus gallus 15377 R-GGA-8864029 https://reactome.org/PathwayBrowser/#/R-GGA-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Gallus gallus 15377 R-GGA-8864036 https://reactome.org/PathwayBrowser/#/R-GGA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Gallus gallus 15377 R-GGA-8864125 https://reactome.org/PathwayBrowser/#/R-GGA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Gallus gallus 15377 R-GGA-8865667 https://reactome.org/PathwayBrowser/#/R-GGA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Gallus gallus 15377 R-GGA-8866542 https://reactome.org/PathwayBrowser/#/R-GGA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Gallus gallus 15377 R-GGA-8866601 https://reactome.org/PathwayBrowser/#/R-GGA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Gallus gallus 15377 R-GGA-8867047 https://reactome.org/PathwayBrowser/#/R-GGA-8867047 PTPN3 dephosphorylates EPS15 IEA Gallus gallus 15377 R-GGA-8867344 https://reactome.org/PathwayBrowser/#/R-GGA-8867344 OMA1 hydrolyses OPA1 IEA Gallus gallus 15377 R-GGA-8867658 https://reactome.org/PathwayBrowser/#/R-GGA-8867658 PTPN3 dephosphorylates MAPK12 IEA Gallus gallus 15377 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus 15377 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus 15377 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus 15377 R-GGA-8869206 https://reactome.org/PathwayBrowser/#/R-GGA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Gallus gallus 15377 R-GGA-8869425 https://reactome.org/PathwayBrowser/#/R-GGA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Gallus gallus 15377 R-GGA-8869456 https://reactome.org/PathwayBrowser/#/R-GGA-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Gallus gallus 15377 R-GGA-8869506 https://reactome.org/PathwayBrowser/#/R-GGA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Gallus gallus 15377 R-GGA-8870346 https://reactome.org/PathwayBrowser/#/R-GGA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Gallus gallus 15377 R-GGA-8875443 https://reactome.org/PathwayBrowser/#/R-GGA-8875443 USP8 deubiquitinates LRIG1 IEA Gallus gallus 15377 R-GGA-8878581 https://reactome.org/PathwayBrowser/#/R-GGA-8878581 TYRP1 oxidises DHICA to IQCA IEA Gallus gallus 15377 R-GGA-8878654 https://reactome.org/PathwayBrowser/#/R-GGA-8878654 ACP6 hydrolyses MYS-LPA IEA Gallus gallus 15377 R-GGA-8878787 https://reactome.org/PathwayBrowser/#/R-GGA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Gallus gallus 15377 R-GGA-888548 https://reactome.org/PathwayBrowser/#/R-GGA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Gallus gallus 15377 R-GGA-8932633 https://reactome.org/PathwayBrowser/#/R-GGA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Gallus gallus 15377 R-GGA-8933328 https://reactome.org/PathwayBrowser/#/R-GGA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Gallus gallus 15377 R-GGA-8933635 https://reactome.org/PathwayBrowser/#/R-GGA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Gallus gallus 15377 R-GGA-8936442 https://reactome.org/PathwayBrowser/#/R-GGA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Gallus gallus 15377 R-GGA-8937442 https://reactome.org/PathwayBrowser/#/R-GGA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Gallus gallus 15377 R-GGA-8937767 https://reactome.org/PathwayBrowser/#/R-GGA-8937767 PTPN11 dephosphorylates RUNX1 IEA Gallus gallus 15377 R-GGA-8938076 https://reactome.org/PathwayBrowser/#/R-GGA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Gallus gallus 15377 R-GGA-8940070 https://reactome.org/PathwayBrowser/#/R-GGA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Gallus gallus 15377 R-GGA-8940074 https://reactome.org/PathwayBrowser/#/R-GGA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Gallus gallus 15377 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus 15377 R-GGA-8943279 https://reactome.org/PathwayBrowser/#/R-GGA-8943279 GGT dimers hydrolyse GSH IEA Gallus gallus 15377 R-GGA-8952137 https://reactome.org/PathwayBrowser/#/R-GGA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Gallus gallus 15377 R-GGA-8952251 https://reactome.org/PathwayBrowser/#/R-GGA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Gallus gallus 15377 R-GGA-8952903 https://reactome.org/PathwayBrowser/#/R-GGA-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Gallus gallus 15377 R-GGA-8954398 https://reactome.org/PathwayBrowser/#/R-GGA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Gallus gallus 15377 R-GGA-8957389 https://reactome.org/PathwayBrowser/#/R-GGA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Gallus gallus 15377 R-GGA-8980228 https://reactome.org/PathwayBrowser/#/R-GGA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Gallus gallus 15377 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus 15377 R-GGA-8985594 https://reactome.org/PathwayBrowser/#/R-GGA-8985594 MYO9B inactivates RHOA IEA Gallus gallus 15377 R-GGA-9008822 https://reactome.org/PathwayBrowser/#/R-GGA-9008822 PPM1D dephosphorylates RUNX2 IEA Gallus gallus 15377 R-GGA-9009950 https://reactome.org/PathwayBrowser/#/R-GGA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Gallus gallus 15377 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus 15377 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus 15377 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus 15377 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus 15377 R-GGA-9013437 https://reactome.org/PathwayBrowser/#/R-GGA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Gallus gallus 15377 R-GGA-9014295 https://reactome.org/PathwayBrowser/#/R-GGA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Gallus gallus 15377 R-GGA-9014434 https://reactome.org/PathwayBrowser/#/R-GGA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Gallus gallus 15377 R-GGA-9014627 https://reactome.org/PathwayBrowser/#/R-GGA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Gallus gallus 15377 R-GGA-9014741 https://reactome.org/PathwayBrowser/#/R-GGA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Gallus gallus 15377 R-GGA-9017488 https://reactome.org/PathwayBrowser/#/R-GGA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Gallus gallus 15377 R-GGA-9018745 https://reactome.org/PathwayBrowser/#/R-GGA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Gallus gallus 15377 R-GGA-9018806 https://reactome.org/PathwayBrowser/#/R-GGA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Gallus gallus 15377 R-GGA-9018814 https://reactome.org/PathwayBrowser/#/R-GGA-9018814 RHOT1 hydrolyzes GTP IEA Gallus gallus 15377 R-GGA-9018826 https://reactome.org/PathwayBrowser/#/R-GGA-9018826 RHOT2 hydrolyzes GTP IEA Gallus gallus 15377 R-GGA-9018862 https://reactome.org/PathwayBrowser/#/R-GGA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Gallus gallus 15377 R-GGA-9018868 https://reactome.org/PathwayBrowser/#/R-GGA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Gallus gallus 15377 R-GGA-9018877 https://reactome.org/PathwayBrowser/#/R-GGA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Gallus gallus 15377 R-GGA-9018895 https://reactome.org/PathwayBrowser/#/R-GGA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Gallus gallus 15377 R-GGA-9020252 https://reactome.org/PathwayBrowser/#/R-GGA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Gallus gallus 15377 R-GGA-9020253 https://reactome.org/PathwayBrowser/#/R-GGA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Gallus gallus 15377 R-GGA-9020257 https://reactome.org/PathwayBrowser/#/R-GGA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Gallus gallus 15377 R-GGA-9020258 https://reactome.org/PathwayBrowser/#/R-GGA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Gallus gallus 15377 R-GGA-9020270 https://reactome.org/PathwayBrowser/#/R-GGA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Gallus gallus 15377 R-GGA-9020271 https://reactome.org/PathwayBrowser/#/R-GGA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Gallus gallus 15377 R-GGA-9020273 https://reactome.org/PathwayBrowser/#/R-GGA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Gallus gallus 15377 R-GGA-9024890 https://reactome.org/PathwayBrowser/#/R-GGA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Gallus gallus 15377 R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus 15377 R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 15377 R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 15377 R-GGA-9033491 https://reactome.org/PathwayBrowser/#/R-GGA-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Gallus gallus 15377 R-GGA-9033520 https://reactome.org/PathwayBrowser/#/R-GGA-9033520 TYSND1 cleaves TYSND1 IEA Gallus gallus 15377 R-GGA-9034539 https://reactome.org/PathwayBrowser/#/R-GGA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Gallus gallus 15377 R-GGA-9037761 https://reactome.org/PathwayBrowser/#/R-GGA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Gallus gallus 15377 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus 15377 R-GGA-917891 https://reactome.org/PathwayBrowser/#/R-GGA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Gallus gallus 15377 R-GGA-917933 https://reactome.org/PathwayBrowser/#/R-GGA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Gallus gallus 15377 R-GGA-936802 https://reactome.org/PathwayBrowser/#/R-GGA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Gallus gallus 15377 R-GGA-936883 https://reactome.org/PathwayBrowser/#/R-GGA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Gallus gallus 15377 R-GGA-936895 https://reactome.org/PathwayBrowser/#/R-GGA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Gallus gallus 15377 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 15377 R-GGA-937311 https://reactome.org/PathwayBrowser/#/R-GGA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Gallus gallus 15377 R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus 15377 R-GGA-947531 https://reactome.org/PathwayBrowser/#/R-GGA-947531 Molybdenum ion transfer onto molybdopterin IEA Gallus gallus 15377 R-GGA-947535 https://reactome.org/PathwayBrowser/#/R-GGA-947535 Cyclisation of GTP to precursor Z IEA Gallus gallus 15377 R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus 15377 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 15377 R-GGA-9620103 https://reactome.org/PathwayBrowser/#/R-GGA-9620103 ALDH2 transforms GTN to NO IEA Gallus gallus 15377 R-GGA-9624893 https://reactome.org/PathwayBrowser/#/R-GGA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Gallus gallus 15377 R-GGA-9629675 https://reactome.org/PathwayBrowser/#/R-GGA-9629675 PDE3A hydrolyses cAMP to AMP IEA Gallus gallus 15377 R-GGA-9638075 https://reactome.org/PathwayBrowser/#/R-GGA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Gallus gallus 15377 R-GGA-9638076 https://reactome.org/PathwayBrowser/#/R-GGA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Gallus gallus 15377 R-GGA-9638078 https://reactome.org/PathwayBrowser/#/R-GGA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Gallus gallus 15377 R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus 15377 R-GGA-9644869 https://reactome.org/PathwayBrowser/#/R-GGA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Gallus gallus 15377 R-GGA-9647994 https://reactome.org/PathwayBrowser/#/R-GGA-9647994 RAS proteins are depalmitoylated IEA Gallus gallus 15377 R-GGA-965079 https://reactome.org/PathwayBrowser/#/R-GGA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Gallus gallus 15377 R-GGA-9656893 https://reactome.org/PathwayBrowser/#/R-GGA-9656893 OPN1MW binds 11cRAL IEA Gallus gallus 15377 R-GGA-9658445 https://reactome.org/PathwayBrowser/#/R-GGA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Gallus gallus 15377 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 15377 R-GGA-9667952 https://reactome.org/PathwayBrowser/#/R-GGA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Gallus gallus 15377 R-GGA-9673053 https://reactome.org/PathwayBrowser/#/R-GGA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Gallus gallus 15377 R-GGA-9673054 https://reactome.org/PathwayBrowser/#/R-GGA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Gallus gallus 15377 R-GGA-9674127 https://reactome.org/PathwayBrowser/#/R-GGA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Gallus gallus 15377 R-GGA-9693282 https://reactome.org/PathwayBrowser/#/R-GGA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Gallus gallus 15377 R-GGA-9700200 https://reactome.org/PathwayBrowser/#/R-GGA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Gallus gallus 15377 R-GGA-9701565 https://reactome.org/PathwayBrowser/#/R-GGA-9701565 HDACs deacetylate p-STAT3 dimers IEA Gallus gallus 15377 R-GGA-9705507 https://reactome.org/PathwayBrowser/#/R-GGA-9705507 PDE3B hydrolyses cAMP to AMP IEA Gallus gallus 15377 R-GGA-9706399 https://reactome.org/PathwayBrowser/#/R-GGA-9706399 RHOBTB3 hydrolyzes ATP IEA Gallus gallus 15377 R-GGA-9709360 https://reactome.org/PathwayBrowser/#/R-GGA-9709360 H2O2 reduces MetHb IEA Gallus gallus 15377 R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 15377 R-GGA-9727349 https://reactome.org/PathwayBrowser/#/R-GGA-9727349 XDH dehydrogenates xanthine to form urate IEA Gallus gallus 15377 R-GGA-9727567 https://reactome.org/PathwayBrowser/#/R-GGA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Gallus gallus 15377 R-GGA-9731228 https://reactome.org/PathwayBrowser/#/R-GGA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Gallus gallus 15377 R-GGA-9731590 https://reactome.org/PathwayBrowser/#/R-GGA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Gallus gallus 15377 R-GGA-9731613 https://reactome.org/PathwayBrowser/#/R-GGA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Gallus gallus 15377 R-GGA-9731632 https://reactome.org/PathwayBrowser/#/R-GGA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Gallus gallus 15377 R-GGA-9731661 https://reactome.org/PathwayBrowser/#/R-GGA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Gallus gallus 15377 R-GGA-9748945 https://reactome.org/PathwayBrowser/#/R-GGA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Gallus gallus 15377 R-GGA-9748957 https://reactome.org/PathwayBrowser/#/R-GGA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Gallus gallus 15377 R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 15377 R-GGA-9749609 https://reactome.org/PathwayBrowser/#/R-GGA-9749609 BCHE hydrolyzes ASA- IEA Gallus gallus 15377 R-GGA-9749647 https://reactome.org/PathwayBrowser/#/R-GGA-9749647 CES2 hydrolyzes ASA- IEA Gallus gallus 15377 R-GGA-9749792 https://reactome.org/PathwayBrowser/#/R-GGA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Gallus gallus 15377 R-GGA-9749986 https://reactome.org/PathwayBrowser/#/R-GGA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Gallus gallus 15377 R-GGA-9750016 https://reactome.org/PathwayBrowser/#/R-GGA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Gallus gallus 15377 R-GGA-9750546 https://reactome.org/PathwayBrowser/#/R-GGA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 15377 R-GGA-9750555 https://reactome.org/PathwayBrowser/#/R-GGA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Gallus gallus 15377 R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 15377 R-GGA-9750656 https://reactome.org/PathwayBrowser/#/R-GGA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Gallus gallus 15377 R-GGA-9750942 https://reactome.org/PathwayBrowser/#/R-GGA-9750942 USP14 deubiquitinates NLRC5 IEA Gallus gallus 15377 R-GGA-9753278 https://reactome.org/PathwayBrowser/#/R-GGA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 15377 R-GGA-9753280 https://reactome.org/PathwayBrowser/#/R-GGA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Gallus gallus 15377 R-GGA-9753283 https://reactome.org/PathwayBrowser/#/R-GGA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 15377 R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 15377 R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus 15377 R-GGA-9753632 https://reactome.org/PathwayBrowser/#/R-GGA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Gallus gallus 15377 R-GGA-9753634 https://reactome.org/PathwayBrowser/#/R-GGA-9753634 GGT dimers hydrolyse APAP-SG IEA Gallus gallus 15377 R-GGA-9753944 https://reactome.org/PathwayBrowser/#/R-GGA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Gallus gallus 15377 R-GGA-9754964 https://reactome.org/PathwayBrowser/#/R-GGA-9754964 ADA deamidates RBV IEA Gallus gallus 15377 R-GGA-9755030 https://reactome.org/PathwayBrowser/#/R-GGA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Gallus gallus 15377 R-GGA-9755078 https://reactome.org/PathwayBrowser/#/R-GGA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Gallus gallus 15377 R-GGA-975593 https://reactome.org/PathwayBrowser/#/R-GGA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Gallus gallus 15377 R-GGA-975594 https://reactome.org/PathwayBrowser/#/R-GGA-975594 PLB1 hydrolyses RPALM to atROL IEA Gallus gallus 15377 R-GGA-9756138 https://reactome.org/PathwayBrowser/#/R-GGA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Gallus gallus 15377 R-GGA-9756162 https://reactome.org/PathwayBrowser/#/R-GGA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Gallus gallus 15377 R-GGA-9756169 https://reactome.org/PathwayBrowser/#/R-GGA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Gallus gallus 15377 R-GGA-9756177 https://reactome.org/PathwayBrowser/#/R-GGA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Gallus gallus 15377 R-GGA-9756180 https://reactome.org/PathwayBrowser/#/R-GGA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Gallus gallus 15377 R-GGA-9758674 https://reactome.org/PathwayBrowser/#/R-GGA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Gallus gallus 15377 R-GGA-9759206 https://reactome.org/PathwayBrowser/#/R-GGA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Gallus gallus 15377 R-GGA-9759454 https://reactome.org/PathwayBrowser/#/R-GGA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Gallus gallus 15377 R-GGA-9759461 https://reactome.org/PathwayBrowser/#/R-GGA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Gallus gallus 15377 R-GGA-977324 https://reactome.org/PathwayBrowser/#/R-GGA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Gallus gallus 15377 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus 15377 R-GGA-9837419 https://reactome.org/PathwayBrowser/#/R-GGA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Gallus gallus 15377 R-GGA-9838004 https://reactome.org/PathwayBrowser/#/R-GGA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Gallus gallus 15377 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus 15377 R-GGA-9839059 https://reactome.org/PathwayBrowser/#/R-GGA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Gallus gallus 15377 R-GGA-9839105 https://reactome.org/PathwayBrowser/#/R-GGA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Gallus gallus 15377 R-GGA-9839113 https://reactome.org/PathwayBrowser/#/R-GGA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Gallus gallus 15377 R-GGA-9840949 https://reactome.org/PathwayBrowser/#/R-GGA-9840949 ARSA removes sulfate from SM3 IEA Gallus gallus 15377 R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 15377 R-GGA-9843721 https://reactome.org/PathwayBrowser/#/R-GGA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Gallus gallus 15377 R-GGA-9853385 https://reactome.org/PathwayBrowser/#/R-GGA-9853385 PPP1CC dephosphorylates PLK1 IEA Gallus gallus 15377 R-GGA-9861626 https://reactome.org/PathwayBrowser/#/R-GGA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Gallus gallus 15377 R-GGA-9861725 https://reactome.org/PathwayBrowser/#/R-GGA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Gallus gallus 15377 R-GGA-997309 https://reactome.org/PathwayBrowser/#/R-GGA-997309 Dephosphorylation of STAT1 by SHP2 IEA Gallus gallus 15377 R-GGA-997311 https://reactome.org/PathwayBrowser/#/R-GGA-997311 Dephosphorylation of TYK2 by PTP1B IEA Gallus gallus 15377 R-GGA-997314 https://reactome.org/PathwayBrowser/#/R-GGA-997314 Dephosphorylation of JAK1 by SHP1 IEA Gallus gallus 15377 R-GGA-997326 https://reactome.org/PathwayBrowser/#/R-GGA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Gallus gallus 15377 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 15377 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 15377 R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 15377 R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 15377 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 15377 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 15377 R-HSA-109415 https://reactome.org/PathwayBrowser/#/R-HSA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] TAS Homo sapiens 15377 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 15377 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 15377 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 15377 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 15377 R-HSA-111742 https://reactome.org/PathwayBrowser/#/R-HSA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 15377 R-HSA-111751 https://reactome.org/PathwayBrowser/#/R-HSA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 15377 R-HSA-111804 https://reactome.org/PathwayBrowser/#/R-HSA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 15377 R-HSA-111879 https://reactome.org/PathwayBrowser/#/R-HSA-111879 PIP2 hydrolysis TAS Homo sapiens 15377 R-HSA-111883 https://reactome.org/PathwayBrowser/#/R-HSA-111883 Hydrolysis of phosphatidylcholine TAS Homo sapiens 15377 R-HSA-111955 https://reactome.org/PathwayBrowser/#/R-HSA-111955 cAMP hydrolysis by Cam-PDE 1 TAS Homo sapiens 15377 R-HSA-111962 https://reactome.org/PathwayBrowser/#/R-HSA-111962 PDE4A,C,D hydrolyse cAMP TAS Homo sapiens 15377 R-HSA-112037 https://reactome.org/PathwayBrowser/#/R-HSA-112037 Inactivation of PLC beta TAS Homo sapiens 15377 R-HSA-113503 https://reactome.org/PathwayBrowser/#/R-HSA-113503 PP2A mediated localization of RB1 protein in chromatin TAS Homo sapiens 15377 R-HSA-1169192 https://reactome.org/PathwayBrowser/#/R-HSA-1169192 PTP1B dephosphorylates GHR TAS Homo sapiens 15377 R-HSA-1169210 https://reactome.org/PathwayBrowser/#/R-HSA-1169210 PTP1B dephosphorylates JAK2 IEA Homo sapiens 15377 R-HSA-1183128 https://reactome.org/PathwayBrowser/#/R-HSA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins TAS Homo sapiens 15377 R-HSA-1222346 https://reactome.org/PathwayBrowser/#/R-HSA-1222346 AhpC reduces H2O2 TAS Homo sapiens 15377 R-HSA-1222431 https://reactome.org/PathwayBrowser/#/R-HSA-1222431 Peroxynitrite is reduced to nitrite by AhpC TAS Homo sapiens 15377 R-HSA-1222526 https://reactome.org/PathwayBrowser/#/R-HSA-1222526 AhpC reduces peroxidated lipids TAS Homo sapiens 15377 R-HSA-1222583 https://reactome.org/PathwayBrowser/#/R-HSA-1222583 MscR reduces nitrosomycothiol to ammonia TAS Homo sapiens 15377 R-HSA-1222704 https://reactome.org/PathwayBrowser/#/R-HSA-1222704 KatG reduces H2O2 TAS Homo sapiens 15377 R-HSA-1222755 https://reactome.org/PathwayBrowser/#/R-HSA-1222755 Peroxynitrite is reduced to nitrite by Tpx TAS Homo sapiens 15377 R-HSA-1236949 https://reactome.org/PathwayBrowser/#/R-HSA-1236949 Translocation of antigenic peptides back to phagosomes via TAP IEA Homo sapiens 15377 R-HSA-1237045 https://reactome.org/PathwayBrowser/#/R-HSA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton TAS Homo sapiens 15377 R-HSA-1237047 https://reactome.org/PathwayBrowser/#/R-HSA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- TAS Homo sapiens 15377 R-HSA-1237059 https://reactome.org/PathwayBrowser/#/R-HSA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 TAS Homo sapiens 15377 R-HSA-1237081 https://reactome.org/PathwayBrowser/#/R-HSA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide TAS Homo sapiens 15377 R-HSA-1237129 https://reactome.org/PathwayBrowser/#/R-HSA-1237129 Acireductone is created TAS Homo sapiens 15377 R-HSA-1237140 https://reactome.org/PathwayBrowser/#/R-HSA-1237140 Dehydration of methylthio-ribulose-P IEA Homo sapiens 15377 R-HSA-1247910 https://reactome.org/PathwayBrowser/#/R-HSA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly TAS Homo sapiens 15377 R-HSA-1247935 https://reactome.org/PathwayBrowser/#/R-HSA-1247935 OPLAH hydrolyses OPRO to L-Glu TAS Homo sapiens 15377 R-HSA-1299476 https://reactome.org/PathwayBrowser/#/R-HSA-1299476 MPP cleaves targeting peptide (presequence) of inner membrane precursors IEA Homo sapiens 15377 R-HSA-1299478 https://reactome.org/PathwayBrowser/#/R-HSA-1299478 MPP cleaves targeting peptide (presequence) of matrix precursors IEA Homo sapiens 15377 R-HSA-1363274 https://reactome.org/PathwayBrowser/#/R-HSA-1363274 Dephosphorylation of p107 (RBL1) by PP2A TAS Homo sapiens 15377 R-HSA-1363276 https://reactome.org/PathwayBrowser/#/R-HSA-1363276 Dephosphorylation of p130 (RBL2) by PP2A TAS Homo sapiens 15377 R-HSA-1369028 https://reactome.org/PathwayBrowser/#/R-HSA-1369028 ABCAs mediate lipid efflux TAS Homo sapiens 15377 R-HSA-1369052 https://reactome.org/PathwayBrowser/#/R-HSA-1369052 ABCAs mediate lipid influx TAS Homo sapiens 15377 R-HSA-1369065 https://reactome.org/PathwayBrowser/#/R-HSA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix TAS Homo sapiens 15377 R-HSA-139906 https://reactome.org/PathwayBrowser/#/R-HSA-139906 Activation of BAD by calcineurin TAS Homo sapiens 15377 R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 15377 R-HSA-140359 https://reactome.org/PathwayBrowser/#/R-HSA-140359 PGG2 is reduced to PGH2 by PTGS1 TAS Homo sapiens 15377 R-HSA-141186 https://reactome.org/PathwayBrowser/#/R-HSA-141186 MAOA:FAD oxidatively deaminates of 5HT TAS Homo sapiens 15377 R-HSA-141200 https://reactome.org/PathwayBrowser/#/R-HSA-141200 MAOB:FAD oxidatively deaminates of PEA TAS Homo sapiens 15377 R-HSA-141202 https://reactome.org/PathwayBrowser/#/R-HSA-141202 MAOB:FAD oxidatively deaminates TYR TAS Homo sapiens 15377 R-HSA-141341 https://reactome.org/PathwayBrowser/#/R-HSA-141341 SMOX-3 oxidises SPN to SPM TAS Homo sapiens 15377 R-HSA-141348 https://reactome.org/PathwayBrowser/#/R-HSA-141348 PAO:FAD oxidises NASPM to PTCN TAS Homo sapiens 15377 R-HSA-141351 https://reactome.org/PathwayBrowser/#/R-HSA-141351 PAOX:FAD oxidises NASPN to SPM TAS Homo sapiens 15377 R-HSA-141673 https://reactome.org/PathwayBrowser/#/R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex IEA Homo sapiens 15377 R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 15377 R-HSA-1454916 https://reactome.org/PathwayBrowser/#/R-HSA-1454916 The ABCC family mediates organic anion transport TAS Homo sapiens 15377 R-HSA-1454928 https://reactome.org/PathwayBrowser/#/R-HSA-1454928 ABCG4 may mediate cholesterol efflux TAS Homo sapiens 15377 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-1467466 https://reactome.org/PathwayBrowser/#/R-HSA-1467466 ABCA4 mediates atRAL transport TAS Homo sapiens 15377 R-HSA-1474146 https://reactome.org/PathwayBrowser/#/R-HSA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate TAS Homo sapiens 15377 R-HSA-1475017 https://reactome.org/PathwayBrowser/#/R-HSA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) TAS Homo sapiens 15377 R-HSA-1475022 https://reactome.org/PathwayBrowser/#/R-HSA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) TAS Homo sapiens 15377 R-HSA-1475025 https://reactome.org/PathwayBrowser/#/R-HSA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) TAS Homo sapiens 15377 R-HSA-1475026 https://reactome.org/PathwayBrowser/#/R-HSA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) TAS Homo sapiens 15377 R-HSA-1475028 https://reactome.org/PathwayBrowser/#/R-HSA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) TAS Homo sapiens 15377 R-HSA-1475032 https://reactome.org/PathwayBrowser/#/R-HSA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) TAS Homo sapiens 15377 R-HSA-1475435 https://reactome.org/PathwayBrowser/#/R-HSA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- TAS Homo sapiens 15377 R-HSA-1475436 https://reactome.org/PathwayBrowser/#/R-HSA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 TAS Homo sapiens 15377 R-HSA-1482543 https://reactome.org/PathwayBrowser/#/R-HSA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL TAS Homo sapiens 15377 R-HSA-1482545 https://reactome.org/PathwayBrowser/#/R-HSA-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C TAS Homo sapiens 15377 R-HSA-1482571 https://reactome.org/PathwayBrowser/#/R-HSA-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C TAS Homo sapiens 15377 R-HSA-1482604 https://reactome.org/PathwayBrowser/#/R-HSA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) TAS Homo sapiens 15377 R-HSA-1482612 https://reactome.org/PathwayBrowser/#/R-HSA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 15377 R-HSA-1482629 https://reactome.org/PathwayBrowser/#/R-HSA-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C TAS Homo sapiens 15377 R-HSA-1482656 https://reactome.org/PathwayBrowser/#/R-HSA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] TAS Homo sapiens 15377 R-HSA-1482679 https://reactome.org/PathwayBrowser/#/R-HSA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A TAS Homo sapiens 15377 R-HSA-1482685 https://reactome.org/PathwayBrowser/#/R-HSA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 15377 R-HSA-1482696 https://reactome.org/PathwayBrowser/#/R-HSA-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C TAS Homo sapiens 15377 R-HSA-1482745 https://reactome.org/PathwayBrowser/#/R-HSA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) TAS Homo sapiens 15377 R-HSA-1482759 https://reactome.org/PathwayBrowser/#/R-HSA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) TAS Homo sapiens 15377 R-HSA-1482771 https://reactome.org/PathwayBrowser/#/R-HSA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] TAS Homo sapiens 15377 R-HSA-1482776 https://reactome.org/PathwayBrowser/#/R-HSA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A TAS Homo sapiens 15377 R-HSA-1482777 https://reactome.org/PathwayBrowser/#/R-HSA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 TAS Homo sapiens 15377 R-HSA-1482778 https://reactome.org/PathwayBrowser/#/R-HSA-1482778 CL is hydrolyzed to MLCL by PLA2G6 (IM) IEA Homo sapiens 15377 R-HSA-1482811 https://reactome.org/PathwayBrowser/#/R-HSA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 TAS Homo sapiens 15377 R-HSA-1482816 https://reactome.org/PathwayBrowser/#/R-HSA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] TAS Homo sapiens 15377 R-HSA-1482825 https://reactome.org/PathwayBrowser/#/R-HSA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] TAS Homo sapiens 15377 R-HSA-1482827 https://reactome.org/PathwayBrowser/#/R-HSA-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C TAS Homo sapiens 15377 R-HSA-1482828 https://reactome.org/PathwayBrowser/#/R-HSA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] TAS Homo sapiens 15377 R-HSA-1482847 https://reactome.org/PathwayBrowser/#/R-HSA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) TAS Homo sapiens 15377 R-HSA-1482856 https://reactome.org/PathwayBrowser/#/R-HSA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] TAS Homo sapiens 15377 R-HSA-1482862 https://reactome.org/PathwayBrowser/#/R-HSA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] TAS Homo sapiens 15377 R-HSA-1482868 https://reactome.org/PathwayBrowser/#/R-HSA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] TAS Homo sapiens 15377 R-HSA-1482884 https://reactome.org/PathwayBrowser/#/R-HSA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] TAS Homo sapiens 15377 R-HSA-1482887 https://reactome.org/PathwayBrowser/#/R-HSA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] TAS Homo sapiens 15377 R-HSA-1482892 https://reactome.org/PathwayBrowser/#/R-HSA-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C TAS Homo sapiens 15377 R-HSA-1482897 https://reactome.org/PathwayBrowser/#/R-HSA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] TAS Homo sapiens 15377 R-HSA-1482900 https://reactome.org/PathwayBrowser/#/R-HSA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] TAS Homo sapiens 15377 R-HSA-1482907 https://reactome.org/PathwayBrowser/#/R-HSA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A TAS Homo sapiens 15377 R-HSA-1482920 https://reactome.org/PathwayBrowser/#/R-HSA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] TAS Homo sapiens 15377 R-HSA-1482932 https://reactome.org/PathwayBrowser/#/R-HSA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] TAS Homo sapiens 15377 R-HSA-1483096 https://reactome.org/PathwayBrowser/#/R-HSA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 TAS Homo sapiens 15377 R-HSA-1483107 https://reactome.org/PathwayBrowser/#/R-HSA-1483107 GPETA is hydrolyzed to ETA and G3P by GPCPD1 IEA Homo sapiens 15377 R-HSA-1483116 https://reactome.org/PathwayBrowser/#/R-HSA-1483116 GPCho is hydrolyzed to Cho and G3P by GPCPD1 IEA Homo sapiens 15377 R-HSA-1483159 https://reactome.org/PathwayBrowser/#/R-HSA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 TAS Homo sapiens 15377 R-HSA-1483182 https://reactome.org/PathwayBrowser/#/R-HSA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 TAS Homo sapiens 15377 R-HSA-1483197 https://reactome.org/PathwayBrowser/#/R-HSA-1483197 PTPMT1 dephosphorylates PGP to PG IEA Homo sapiens 15377 R-HSA-1483203 https://reactome.org/PathwayBrowser/#/R-HSA-1483203 PA is dephosphorylated to DAG by LPIN TAS Homo sapiens 15377 R-HSA-1500761 https://reactome.org/PathwayBrowser/#/R-HSA-1500761 Nitrogen dioxide is reduced to NO by F420 TAS Homo sapiens 15377 R-HSA-1500804 https://reactome.org/PathwayBrowser/#/R-HSA-1500804 Peroxynitrite is reduced by AhpE TAS Homo sapiens 15377 R-HSA-1562603 https://reactome.org/PathwayBrowser/#/R-HSA-1562603 BfrB stores iron TAS Homo sapiens 15377 R-HSA-1562604 https://reactome.org/PathwayBrowser/#/R-HSA-1562604 BfrA stores iron TAS Homo sapiens 15377 R-HSA-156526 https://reactome.org/PathwayBrowser/#/R-HSA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO TAS Homo sapiens 15377 R-HSA-159425 https://reactome.org/PathwayBrowser/#/R-HSA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 15377 R-HSA-159752 https://reactome.org/PathwayBrowser/#/R-HSA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) TAS Homo sapiens 15377 R-HSA-159761 https://reactome.org/PathwayBrowser/#/R-HSA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) TAS Homo sapiens 15377 R-HSA-159795 https://reactome.org/PathwayBrowser/#/R-HSA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) TAS Homo sapiens 15377 R-HSA-159803 https://reactome.org/PathwayBrowser/#/R-HSA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) TAS Homo sapiens 15377 R-HSA-159819 https://reactome.org/PathwayBrowser/#/R-HSA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) TAS Homo sapiens 15377 R-HSA-159826 https://reactome.org/PathwayBrowser/#/R-HSA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) TAS Homo sapiens 15377 R-HSA-1602368 https://reactome.org/PathwayBrowser/#/R-HSA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] TAS Homo sapiens 15377 R-HSA-1602374 https://reactome.org/PathwayBrowser/#/R-HSA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] TAS Homo sapiens 15377 R-HSA-1602377 https://reactome.org/PathwayBrowser/#/R-HSA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] TAS Homo sapiens 15377 R-HSA-1602398 https://reactome.org/PathwayBrowser/#/R-HSA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] TAS Homo sapiens 15377 R-HSA-1602399 https://reactome.org/PathwayBrowser/#/R-HSA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 TAS Homo sapiens 15377 R-HSA-1602417 https://reactome.org/PathwayBrowser/#/R-HSA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] TAS Homo sapiens 15377 R-HSA-1602446 https://reactome.org/PathwayBrowser/#/R-HSA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] TAS Homo sapiens 15377 R-HSA-1605591 https://reactome.org/PathwayBrowser/#/R-HSA-1605591 GBA1:SAPC hydrolyzes GlcCer TAS Homo sapiens 15377 R-HSA-1605595 https://reactome.org/PathwayBrowser/#/R-HSA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 TAS Homo sapiens 15377 R-HSA-1605624 https://reactome.org/PathwayBrowser/#/R-HSA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 TAS Homo sapiens 15377 R-HSA-1605632 https://reactome.org/PathwayBrowser/#/R-HSA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE TAS Homo sapiens 15377 R-HSA-1605723 https://reactome.org/PathwayBrowser/#/R-HSA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) TAS Homo sapiens 15377 R-HSA-1605724 https://reactome.org/PathwayBrowser/#/R-HSA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE TAS Homo sapiens 15377 R-HSA-1605736 https://reactome.org/PathwayBrowser/#/R-HSA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE TAS Homo sapiens 15377 R-HSA-1605768 https://reactome.org/PathwayBrowser/#/R-HSA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) TAS Homo sapiens 15377 R-HSA-1605797 https://reactome.org/PathwayBrowser/#/R-HSA-1605797 SMPD1 hydrolyzes SPHM TAS Homo sapiens 15377 R-HSA-1606273 https://reactome.org/PathwayBrowser/#/R-HSA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) TAS Homo sapiens 15377 R-HSA-1606288 https://reactome.org/PathwayBrowser/#/R-HSA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) TAS Homo sapiens 15377 R-HSA-1606312 https://reactome.org/PathwayBrowser/#/R-HSA-1606312 GLB1 hydrolyzes SapB/C:LacCer TAS Homo sapiens 15377 R-HSA-1606564 https://reactome.org/PathwayBrowser/#/R-HSA-1606564 GALC hydrolyzes GalCer TAS Homo sapiens 15377 R-HSA-1606583 https://reactome.org/PathwayBrowser/#/R-HSA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) TAS Homo sapiens 15377 R-HSA-1606602 https://reactome.org/PathwayBrowser/#/R-HSA-1606602 ASAH1 hydrolyzes ceramide TAS Homo sapiens 15377 R-HSA-1606789 https://reactome.org/PathwayBrowser/#/R-HSA-1606789 ARSB hydrolyses DS TAS Homo sapiens 15377 R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 15377 R-HSA-1606839 https://reactome.org/PathwayBrowser/#/R-HSA-1606839 ARSC hydrolyzes steroid sulfates TAS Homo sapiens 15377 R-HSA-1614524 https://reactome.org/PathwayBrowser/#/R-HSA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine TAS Homo sapiens 15377 R-HSA-1614544 https://reactome.org/PathwayBrowser/#/R-HSA-1614544 Sulfite is oxidized to sulfate TAS Homo sapiens 15377 R-HSA-1614583 https://reactome.org/PathwayBrowser/#/R-HSA-1614583 PXLP-K212-CTH cleaves L-Cystathionine TAS Homo sapiens 15377 R-HSA-1614605 https://reactome.org/PathwayBrowser/#/R-HSA-1614605 Persulfide sulfur is dioxygenated TAS Homo sapiens 15377 R-HSA-1614614 https://reactome.org/PathwayBrowser/#/R-HSA-1614614 Cysteine is degraded to serine and H2S TAS Homo sapiens 15377 R-HSA-1614631 https://reactome.org/PathwayBrowser/#/R-HSA-1614631 Homocysteine is degraded to oxobutanoate and H2S TAS Homo sapiens 15377 R-HSA-162425 https://reactome.org/PathwayBrowser/#/R-HSA-162425 p-S295-PDE3B hydrolyses cAMP to AMP TAS Homo sapiens 15377 R-HSA-162729 https://reactome.org/PathwayBrowser/#/R-HSA-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid TAS Homo sapiens 15377 R-HSA-162857 https://reactome.org/PathwayBrowser/#/R-HSA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate TAS Homo sapiens 15377 R-HSA-1630304 https://reactome.org/PathwayBrowser/#/R-HSA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate TAS Homo sapiens 15377 R-HSA-1630306 https://reactome.org/PathwayBrowser/#/R-HSA-1630306 GLB1 hydrolyses a glycosaminoglycan TAS Homo sapiens 15377 R-HSA-163120 https://reactome.org/PathwayBrowser/#/R-HSA-163120 Disassociation of Telomerase RNP and the Chromosome End TAS Homo sapiens 15377 R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 15377 R-HSA-163402 https://reactome.org/PathwayBrowser/#/R-HSA-163402 diacylglycerol + H2O -> 2-acylglycerol + fatty acid IEA Homo sapiens 15377 R-HSA-163432 https://reactome.org/PathwayBrowser/#/R-HSA-163432 cholesterol ester + H2O -> cholesterol + fatty acid IEA Homo sapiens 15377 R-HSA-163489 https://reactome.org/PathwayBrowser/#/R-HSA-163489 phosphorylated HSL + H2O -> HSL + orthophosphate IEA Homo sapiens 15377 R-HSA-163551 https://reactome.org/PathwayBrowser/#/R-HSA-163551 triacylglycerol + H2O -> diacylglycerol + fatty acid IEA Homo sapiens 15377 R-HSA-163568 https://reactome.org/PathwayBrowser/#/R-HSA-163568 phosphorylated perilipin + H2O -> perilipin + orthophosphate IEA Homo sapiens 15377 R-HSA-163595 https://reactome.org/PathwayBrowser/#/R-HSA-163595 2-acylglycerol + H2O -> glycerol + fatty acid IEA Homo sapiens 15377 R-HSA-163750 https://reactome.org/PathwayBrowser/#/R-HSA-163750 Dephosphorylation of phosphoPFKFB1 by PP2A complex IEA Homo sapiens 15377 R-HSA-1638032 https://reactome.org/PathwayBrowser/#/R-HSA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate TAS Homo sapiens 15377 R-HSA-1638053 https://reactome.org/PathwayBrowser/#/R-HSA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate TAS Homo sapiens 15377 R-HSA-163810 https://reactome.org/PathwayBrowser/#/R-HSA-163810 GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6) IEA Homo sapiens 15377 R-HSA-163820 https://reactome.org/PathwayBrowser/#/R-HSA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) TAS Homo sapiens 15377 R-HSA-1638821 https://reactome.org/PathwayBrowser/#/R-HSA-1638821 PP2A-B56 dephosphorylates centromeric cohesin TAS Homo sapiens 15377 R-HSA-1640164 https://reactome.org/PathwayBrowser/#/R-HSA-1640164 ENPP7 hydrolyzes sphingomyelin TAS Homo sapiens 15377 R-HSA-164832 https://reactome.org/PathwayBrowser/#/R-HSA-164832 ATPase synthesizes ATP TAS Homo sapiens 15377 R-HSA-1655453 https://reactome.org/PathwayBrowser/#/R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU TAS Homo sapiens 15377 R-HSA-1667005 https://reactome.org/PathwayBrowser/#/R-HSA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) TAS Homo sapiens 15377 R-HSA-1675795 https://reactome.org/PathwayBrowser/#/R-HSA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane TAS Homo sapiens 15377 R-HSA-1675824 https://reactome.org/PathwayBrowser/#/R-HSA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane TAS Homo sapiens 15377 R-HSA-1675836 https://reactome.org/PathwayBrowser/#/R-HSA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane TAS Homo sapiens 15377 R-HSA-1675949 https://reactome.org/PathwayBrowser/#/R-HSA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane TAS Homo sapiens 15377 R-HSA-1675988 https://reactome.org/PathwayBrowser/#/R-HSA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane TAS Homo sapiens 15377 R-HSA-1675994 https://reactome.org/PathwayBrowser/#/R-HSA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane TAS Homo sapiens 15377 R-HSA-1676005 https://reactome.org/PathwayBrowser/#/R-HSA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane TAS Homo sapiens 15377 R-HSA-1676020 https://reactome.org/PathwayBrowser/#/R-HSA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane TAS Homo sapiens 15377 R-HSA-1676065 https://reactome.org/PathwayBrowser/#/R-HSA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane TAS Homo sapiens 15377 R-HSA-1676105 https://reactome.org/PathwayBrowser/#/R-HSA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane TAS Homo sapiens 15377 R-HSA-1676114 https://reactome.org/PathwayBrowser/#/R-HSA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane TAS Homo sapiens 15377 R-HSA-1676124 https://reactome.org/PathwayBrowser/#/R-HSA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane TAS Homo sapiens 15377 R-HSA-1676141 https://reactome.org/PathwayBrowser/#/R-HSA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane TAS Homo sapiens 15377 R-HSA-1676149 https://reactome.org/PathwayBrowser/#/R-HSA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane TAS Homo sapiens 15377 R-HSA-1676162 https://reactome.org/PathwayBrowser/#/R-HSA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane TAS Homo sapiens 15377 R-HSA-1676164 https://reactome.org/PathwayBrowser/#/R-HSA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane TAS Homo sapiens 15377 R-HSA-1676174 https://reactome.org/PathwayBrowser/#/R-HSA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane TAS Homo sapiens 15377 R-HSA-1676177 https://reactome.org/PathwayBrowser/#/R-HSA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane TAS Homo sapiens 15377 R-HSA-1676203 https://reactome.org/PathwayBrowser/#/R-HSA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane TAS Homo sapiens 15377 R-HSA-1676204 https://reactome.org/PathwayBrowser/#/R-HSA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane TAS Homo sapiens 15377 R-HSA-167686 https://reactome.org/PathwayBrowser/#/R-HSA-167686 Active PLCG1 hydrolyses PIP2 IEA Homo sapiens 15377 R-HSA-1678650 https://reactome.org/PathwayBrowser/#/R-HSA-1678650 IDS hydrolyses Heparan sulfate chain(5) TAS Homo sapiens 15377 R-HSA-1678708 https://reactome.org/PathwayBrowser/#/R-HSA-1678708 SGSH hydrolyses Heparan sulfate chain(2) TAS Homo sapiens 15377 R-HSA-1678716 https://reactome.org/PathwayBrowser/#/R-HSA-1678716 IDUA hydrolyses Heparan sulfate chain(1) TAS Homo sapiens 15377 R-HSA-1678742 https://reactome.org/PathwayBrowser/#/R-HSA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) TAS Homo sapiens 15377 R-HSA-1678854 https://reactome.org/PathwayBrowser/#/R-HSA-1678854 GUSB tetramer hydrolyses CS/HS precursor TAS Homo sapiens 15377 R-HSA-170153 https://reactome.org/PathwayBrowser/#/R-HSA-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases TAS Homo sapiens 15377 R-HSA-170158 https://reactome.org/PathwayBrowser/#/R-HSA-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes TAS Homo sapiens 15377 R-HSA-170161 https://reactome.org/PathwayBrowser/#/R-HSA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B TAS Homo sapiens 15377 R-HSA-173597 https://reactome.org/PathwayBrowser/#/R-HSA-173597 UDP-glucose is oxidised to UDP-glucuronate TAS Homo sapiens 15377 R-HSA-173739 https://reactome.org/PathwayBrowser/#/R-HSA-173739 Spontaneous hydrolysis of C3 thioester TAS Homo sapiens 15377 R-HSA-174110 https://reactome.org/PathwayBrowser/#/R-HSA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 TAS Homo sapiens 15377 R-HSA-174124 https://reactome.org/PathwayBrowser/#/R-HSA-174124 Dephosphorylation of phospho-Cdh1 TAS Homo sapiens 15377 R-HSA-174391 https://reactome.org/PathwayBrowser/#/R-HSA-174391 MAT1A multimers transfer Ado from ATP to L-Met TAS Homo sapiens 15377 R-HSA-174401 https://reactome.org/PathwayBrowser/#/R-HSA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy TAS Homo sapiens 15377 R-HSA-174438 https://reactome.org/PathwayBrowser/#/R-HSA-174438 Formation of the Flap Intermediate on the C-strand TAS Homo sapiens 15377 R-HSA-174439 https://reactome.org/PathwayBrowser/#/R-HSA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere TAS Homo sapiens 15377 R-HSA-176606 https://reactome.org/PathwayBrowser/#/R-HSA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate TAS Homo sapiens 15377 R-HSA-177501 https://reactome.org/PathwayBrowser/#/R-HSA-177501 Endocytosis (internalization) of clathrin-coated vesicle IEA Homo sapiens 15377 R-HSA-177923 https://reactome.org/PathwayBrowser/#/R-HSA-177923 Sustained activation of SRC kinase by SHP2 TAS Homo sapiens 15377 R-HSA-177924 https://reactome.org/PathwayBrowser/#/R-HSA-177924 Dephosphorylation of Gab1 by SHP2 TAS Homo sapiens 15377 R-HSA-177926 https://reactome.org/PathwayBrowser/#/R-HSA-177926 Dephosphorylation of PAG by SHP2 TAS Homo sapiens 15377 R-HSA-177935 https://reactome.org/PathwayBrowser/#/R-HSA-177935 SHP2 dephosphorylates Tyr 992 on EGFR TAS Homo sapiens 15377 R-HSA-178178 https://reactome.org/PathwayBrowser/#/R-HSA-178178 PP1 dephosphorylates TGFBR1 IEA Homo sapiens 15377 R-HSA-1793176 https://reactome.org/PathwayBrowser/#/R-HSA-1793176 DS is cleaved from its proteoglycan TAS Homo sapiens 15377 R-HSA-1793182 https://reactome.org/PathwayBrowser/#/R-HSA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) TAS Homo sapiens 15377 R-HSA-1793186 https://reactome.org/PathwayBrowser/#/R-HSA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS TAS Homo sapiens 15377 R-HSA-1793207 https://reactome.org/PathwayBrowser/#/R-HSA-1793207 ARSB hydrolyses C4S/C6S chains TAS Homo sapiens 15377 R-HSA-1793209 https://reactome.org/PathwayBrowser/#/R-HSA-1793209 HYAL1 hydrolyses Chondroitin chains TAS Homo sapiens 15377 R-HSA-1793217 https://reactome.org/PathwayBrowser/#/R-HSA-1793217 Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase TAS Homo sapiens 15377 R-HSA-180632 https://reactome.org/PathwayBrowser/#/R-HSA-180632 Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand TAS Homo sapiens 15377 R-HSA-1855154 https://reactome.org/PathwayBrowser/#/R-HSA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 15377 R-HSA-1855159 https://reactome.org/PathwayBrowser/#/R-HSA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol TAS Homo sapiens 15377 R-HSA-1855163 https://reactome.org/PathwayBrowser/#/R-HSA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen TAS Homo sapiens 15377 R-HSA-1855165 https://reactome.org/PathwayBrowser/#/R-HSA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 15377 R-HSA-1855166 https://reactome.org/PathwayBrowser/#/R-HSA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol TAS Homo sapiens 15377 R-HSA-1855171 https://reactome.org/PathwayBrowser/#/R-HSA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol TAS Homo sapiens 15377 R-HSA-1855174 https://reactome.org/PathwayBrowser/#/R-HSA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol TAS Homo sapiens 15377 R-HSA-1855177 https://reactome.org/PathwayBrowser/#/R-HSA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane TAS Homo sapiens 15377 R-HSA-1855180 https://reactome.org/PathwayBrowser/#/R-HSA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol TAS Homo sapiens 15377 R-HSA-1855198 https://reactome.org/PathwayBrowser/#/R-HSA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 15377 R-HSA-1855200 https://reactome.org/PathwayBrowser/#/R-HSA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen TAS Homo sapiens 15377 R-HSA-1855202 https://reactome.org/PathwayBrowser/#/R-HSA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol TAS Homo sapiens 15377 R-HSA-1855205 https://reactome.org/PathwayBrowser/#/R-HSA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol TAS Homo sapiens 15377 R-HSA-1855208 https://reactome.org/PathwayBrowser/#/R-HSA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol TAS Homo sapiens 15377 R-HSA-1855210 https://reactome.org/PathwayBrowser/#/R-HSA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 15377 R-HSA-1855211 https://reactome.org/PathwayBrowser/#/R-HSA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 15377 R-HSA-1855213 https://reactome.org/PathwayBrowser/#/R-HSA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane TAS Homo sapiens 15377 R-HSA-1855214 https://reactome.org/PathwayBrowser/#/R-HSA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane TAS Homo sapiens 15377 R-HSA-1855218 https://reactome.org/PathwayBrowser/#/R-HSA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol TAS Homo sapiens 15377 R-HSA-1855219 https://reactome.org/PathwayBrowser/#/R-HSA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 15377 R-HSA-1855221 https://reactome.org/PathwayBrowser/#/R-HSA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane TAS Homo sapiens 15377 R-HSA-1855222 https://reactome.org/PathwayBrowser/#/R-HSA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane TAS Homo sapiens 15377 R-HSA-1855225 https://reactome.org/PathwayBrowser/#/R-HSA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen TAS Homo sapiens 15377 R-HSA-1855232 https://reactome.org/PathwayBrowser/#/R-HSA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol TAS Homo sapiens 15377 R-HSA-1861788 https://reactome.org/PathwayBrowser/#/R-HSA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) TAS Homo sapiens 15377 R-HSA-1861789 https://reactome.org/PathwayBrowser/#/R-HSA-1861789 GBA3 hydrolyzes GlcCer (cytosol) TAS Homo sapiens 15377 R-HSA-188979 https://reactome.org/PathwayBrowser/#/R-HSA-188979 Digestion of linear starch (amylose) by extracellular amylase TAS Homo sapiens 15377 R-HSA-188985 https://reactome.org/PathwayBrowser/#/R-HSA-188985 trehalose + H2O => 2 D-glucose IEA Homo sapiens 15377 R-HSA-189053 https://reactome.org/PathwayBrowser/#/R-HSA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose TAS Homo sapiens 15377 R-HSA-189062 https://reactome.org/PathwayBrowser/#/R-HSA-189062 lactose + H2O => D-glucose + D-galactose TAS Homo sapiens 15377 R-HSA-189069 https://reactome.org/PathwayBrowser/#/R-HSA-189069 sucrose + H2O => glucose + fructose TAS Homo sapiens 15377 R-HSA-189102 https://reactome.org/PathwayBrowser/#/R-HSA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) TAS Homo sapiens 15377 R-HSA-189398 https://reactome.org/PathwayBrowser/#/R-HSA-189398 HMOX1 dimer, HMOX2 cleave heme TAS Homo sapiens 15377 R-HSA-189406 https://reactome.org/PathwayBrowser/#/R-HSA-189406 4 PBGs bind to form HMB TAS Homo sapiens 15377 R-HSA-189421 https://reactome.org/PathwayBrowser/#/R-HSA-189421 CPO transforms COPRO3 to PPGEN9 TAS Homo sapiens 15377 R-HSA-189439 https://reactome.org/PathwayBrowser/#/R-HSA-189439 ALAD condenses 2 dALAs to form PBG TAS Homo sapiens 15377 R-HSA-189488 https://reactome.org/PathwayBrowser/#/R-HSA-189488 UROS transforms HMB to URO3 TAS Homo sapiens 15377 R-HSA-190168 https://reactome.org/PathwayBrowser/#/R-HSA-190168 HMBL spontaneously transforms to URO1 TAS Homo sapiens 15377 R-HSA-191101 https://reactome.org/PathwayBrowser/#/R-HSA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) TAS Homo sapiens 15377 R-HSA-191108 https://reactome.org/PathwayBrowser/#/R-HSA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) TAS Homo sapiens 15377 R-HSA-191114 https://reactome.org/PathwayBrowser/#/R-HSA-191114 Digestion of branched starch (amylopectin) by extracellular amylase TAS Homo sapiens 15377 R-HSA-191116 https://reactome.org/PathwayBrowser/#/R-HSA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) TAS Homo sapiens 15377 R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 15377 R-HSA-191323 https://reactome.org/PathwayBrowser/#/R-HSA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA TAS Homo sapiens 15377 R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 15377 R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 15377 R-HSA-191999 https://reactome.org/PathwayBrowser/#/R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol TAS Homo sapiens 15377 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 15377 R-HSA-192054 https://reactome.org/PathwayBrowser/#/R-HSA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) TAS Homo sapiens 15377 R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 15377 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 15377 R-HSA-192123 https://reactome.org/PathwayBrowser/#/R-HSA-192123 CYP27A1 27-hydroxylates CHOL TAS Homo sapiens 15377 R-HSA-192157 https://reactome.org/PathwayBrowser/#/R-HSA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE TAS Homo sapiens 15377 R-HSA-192178 https://reactome.org/PathwayBrowser/#/R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL TAS Homo sapiens 15377 R-HSA-192331 https://reactome.org/PathwayBrowser/#/R-HSA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA TAS Homo sapiens 15377 R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 15377 R-HSA-192422 https://reactome.org/PathwayBrowser/#/R-HSA-192422 Digestion of triacylglycerols by extracellular PTL:colipase TAS Homo sapiens 15377 R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 15377 R-HSA-192430 https://reactome.org/PathwayBrowser/#/R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 15377 R-HSA-192434 https://reactome.org/PathwayBrowser/#/R-HSA-192434 Digestion of diacylglycerols by extracellular PTL:colipase TAS Homo sapiens 15377 R-HSA-192475 https://reactome.org/PathwayBrowser/#/R-HSA-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 TAS Homo sapiens 15377 R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 15377 R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 15377 R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 15377 R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 15377 R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 15377 R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 15377 R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 15377 R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 15377 R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 15377 R-HSA-193362 https://reactome.org/PathwayBrowser/#/R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-193385 https://reactome.org/PathwayBrowser/#/R-HSA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH TAS Homo sapiens 15377 R-HSA-193393 https://reactome.org/PathwayBrowser/#/R-HSA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol TAS Homo sapiens 15377 R-HSA-193460 https://reactome.org/PathwayBrowser/#/R-HSA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) TAS Homo sapiens 15377 R-HSA-193535 https://reactome.org/PathwayBrowser/#/R-HSA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA TAS Homo sapiens 15377 R-HSA-193706 https://reactome.org/PathwayBrowser/#/R-HSA-193706 Production of ceramide which can activate JNK and other targets IEA Homo sapiens 15377 R-HSA-193709 https://reactome.org/PathwayBrowser/#/R-HSA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL TAS Homo sapiens 15377 R-HSA-193711 https://reactome.org/PathwayBrowser/#/R-HSA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 15377 R-HSA-193713 https://reactome.org/PathwayBrowser/#/R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) TAS Homo sapiens 15377 R-HSA-193719 https://reactome.org/PathwayBrowser/#/R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 15377 R-HSA-193727 https://reactome.org/PathwayBrowser/#/R-HSA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 15377 R-HSA-193737 https://reactome.org/PathwayBrowser/#/R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) TAS Homo sapiens 15377 R-HSA-193743 https://reactome.org/PathwayBrowser/#/R-HSA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 15377 R-HSA-193766 https://reactome.org/PathwayBrowser/#/R-HSA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 15377 R-HSA-193780 https://reactome.org/PathwayBrowser/#/R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al TAS Homo sapiens 15377 R-HSA-193787 https://reactome.org/PathwayBrowser/#/R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol TAS Homo sapiens 15377 R-HSA-193792 https://reactome.org/PathwayBrowser/#/R-HSA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 15377 R-HSA-193845 https://reactome.org/PathwayBrowser/#/R-HSA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE TAS Homo sapiens 15377 R-HSA-193964 https://reactome.org/PathwayBrowser/#/R-HSA-193964 CYP21A2 21-hydroxylates PROG TAS Homo sapiens 15377 R-HSA-193965 https://reactome.org/PathwayBrowser/#/R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO TAS Homo sapiens 15377 R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 15377 R-HSA-193995 https://reactome.org/PathwayBrowser/#/R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST TAS Homo sapiens 15377 R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 15377 R-HSA-194017 https://reactome.org/PathwayBrowser/#/R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST TAS Homo sapiens 15377 R-HSA-194641 https://reactome.org/PathwayBrowser/#/R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15377 R-HSA-194669 https://reactome.org/PathwayBrowser/#/R-HSA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15377 R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 15377 R-HSA-195664 https://reactome.org/PathwayBrowser/#/R-HSA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol TAS Homo sapiens 15377 R-HSA-196950 https://reactome.org/PathwayBrowser/#/R-HSA-196950 2xTRAP hydrolyzes FMN to RIB TAS Homo sapiens 15377 R-HSA-196955 https://reactome.org/PathwayBrowser/#/R-HSA-196955 2xENPP1 hydrolyzes FAD to FMN TAS Homo sapiens 15377 R-HSA-197187 https://reactome.org/PathwayBrowser/#/R-HSA-197187 ACS transforms to QUIN non-enzymatically TAS Homo sapiens 15377 R-HSA-197271 https://reactome.org/PathwayBrowser/#/R-HSA-197271 NADSYN1 hexamer amidates NAAD to NAD+ TAS Homo sapiens 15377 R-HSA-199425 https://reactome.org/PathwayBrowser/#/R-HSA-199425 PHLPP dephosphorylates S473 in AKT TAS Homo sapiens 15377 R-HSA-199456 https://reactome.org/PathwayBrowser/#/R-HSA-199456 PTEN dephosphorylates PIP3 TAS Homo sapiens 15377 R-HSA-199959 https://reactome.org/PathwayBrowser/#/R-HSA-199959 ERKs are inactivated by protein phosphatase 2A TAS Homo sapiens 15377 R-HSA-2002466 https://reactome.org/PathwayBrowser/#/R-HSA-2002466 Formation of allysine by LOX TAS Homo sapiens 15377 R-HSA-200661 https://reactome.org/PathwayBrowser/#/R-HSA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG TAS Homo sapiens 15377 R-HSA-200740 https://reactome.org/PathwayBrowser/#/R-HSA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate TAS Homo sapiens 15377 R-HSA-201035 https://reactome.org/PathwayBrowser/#/R-HSA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA TAS Homo sapiens 15377 R-HSA-201787 https://reactome.org/PathwayBrowser/#/R-HSA-201787 PPP3 complex dephosphorylates DARPP-32 on Thr34 IEA Homo sapiens 15377 R-HSA-201790 https://reactome.org/PathwayBrowser/#/R-HSA-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A TAS Homo sapiens 15377 R-HSA-202214 https://reactome.org/PathwayBrowser/#/R-HSA-202214 Dephosphorylation of Lck-pY505 by CD45 TAS Homo sapiens 15377 R-HSA-2022368 https://reactome.org/PathwayBrowser/#/R-HSA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) TAS Homo sapiens 15377 R-HSA-202237 https://reactome.org/PathwayBrowser/#/R-HSA-202237 Hydrolysis of PIP3 to PI(3,4)P2 TAS Homo sapiens 15377 R-HSA-2022378 https://reactome.org/PathwayBrowser/#/R-HSA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) TAS Homo sapiens 15377 R-HSA-2022379 https://reactome.org/PathwayBrowser/#/R-HSA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) TAS Homo sapiens 15377 R-HSA-2022381 https://reactome.org/PathwayBrowser/#/R-HSA-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 15377 R-HSA-2022383 https://reactome.org/PathwayBrowser/#/R-HSA-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 15377 R-HSA-2022393 https://reactome.org/PathwayBrowser/#/R-HSA-2022393 ANPEP:Zn2+ hydrolyzes Angiotensin-(2-8) to Angiotensin-(3-8) IEA Homo sapiens 15377 R-HSA-2022396 https://reactome.org/PathwayBrowser/#/R-HSA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) TAS Homo sapiens 15377 R-HSA-2022398 https://reactome.org/PathwayBrowser/#/R-HSA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) TAS Homo sapiens 15377 R-HSA-2022399 https://reactome.org/PathwayBrowser/#/R-HSA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) TAS Homo sapiens 15377 R-HSA-2022403 https://reactome.org/PathwayBrowser/#/R-HSA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) TAS Homo sapiens 15377 R-HSA-2022405 https://reactome.org/PathwayBrowser/#/R-HSA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 15377 R-HSA-2022411 https://reactome.org/PathwayBrowser/#/R-HSA-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 15377 R-HSA-2022412 https://reactome.org/PathwayBrowser/#/R-HSA-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) TAS Homo sapiens 15377 R-HSA-2022887 https://reactome.org/PathwayBrowser/#/R-HSA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan TAS Homo sapiens 15377 R-HSA-2023971 https://reactome.org/PathwayBrowser/#/R-HSA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 15377 R-HSA-2023973 https://reactome.org/PathwayBrowser/#/R-HSA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 15377 R-HSA-202407 https://reactome.org/PathwayBrowser/#/R-HSA-202407 PLC-gamma1 hydrolyses PIP2 TAS Homo sapiens 15377 R-HSA-2028294 https://reactome.org/PathwayBrowser/#/R-HSA-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) TAS Homo sapiens 15377 R-HSA-2029468 https://reactome.org/PathwayBrowser/#/R-HSA-2029468 Conversion of PA into DAG by PAP-1 TAS Homo sapiens 15377 R-HSA-2029471 https://reactome.org/PathwayBrowser/#/R-HSA-2029471 Hydrolysis of PC to PA by PLD TAS Homo sapiens 15377 R-HSA-2029475 https://reactome.org/PathwayBrowser/#/R-HSA-2029475 Production of AA by iPLA2 upon FCGR activation TAS Homo sapiens 15377 R-HSA-203797 https://reactome.org/PathwayBrowser/#/R-HSA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) TAS Homo sapiens 15377 R-HSA-204169 https://reactome.org/PathwayBrowser/#/R-HSA-204169 PDP1,2 dephosphorylate p-lipo-PDH TAS Homo sapiens 15377 R-HSA-2046083 https://reactome.org/PathwayBrowser/#/R-HSA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA TAS Homo sapiens 15377 R-HSA-2046084 https://reactome.org/PathwayBrowser/#/R-HSA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA TAS Homo sapiens 15377 R-HSA-2046088 https://reactome.org/PathwayBrowser/#/R-HSA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA TAS Homo sapiens 15377 R-HSA-2046089 https://reactome.org/PathwayBrowser/#/R-HSA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA TAS Homo sapiens 15377 R-HSA-2046090 https://reactome.org/PathwayBrowser/#/R-HSA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 15377 R-HSA-2046092 https://reactome.org/PathwayBrowser/#/R-HSA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA TAS Homo sapiens 15377 R-HSA-2046094 https://reactome.org/PathwayBrowser/#/R-HSA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA TAS Homo sapiens 15377 R-HSA-2046095 https://reactome.org/PathwayBrowser/#/R-HSA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA TAS Homo sapiens 15377 R-HSA-2046096 https://reactome.org/PathwayBrowser/#/R-HSA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA TAS Homo sapiens 15377 R-HSA-2046097 https://reactome.org/PathwayBrowser/#/R-HSA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 15377 R-HSA-2046099 https://reactome.org/PathwayBrowser/#/R-HSA-2046099 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA IEA Homo sapiens 15377 R-HSA-2046100 https://reactome.org/PathwayBrowser/#/R-HSA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA TAS Homo sapiens 15377 R-HSA-204662 https://reactome.org/PathwayBrowser/#/R-HSA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A TAS Homo sapiens 15377 R-HSA-2065233 https://reactome.org/PathwayBrowser/#/R-HSA-2065233 CS is cleaved from its proteoglycan TAS Homo sapiens 15377 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 15377 R-HSA-2065357 https://reactome.org/PathwayBrowser/#/R-HSA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) TAS Homo sapiens 15377 R-HSA-2066778 https://reactome.org/PathwayBrowser/#/R-HSA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA TAS Homo sapiens 15377 R-HSA-2066779 https://reactome.org/PathwayBrowser/#/R-HSA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) TAS Homo sapiens 15377 R-HSA-2090037 https://reactome.org/PathwayBrowser/#/R-HSA-2090037 IDUA hydrolyses Heparan sulfate chain(6) TAS Homo sapiens 15377 R-HSA-2090038 https://reactome.org/PathwayBrowser/#/R-HSA-2090038 NAGLU hydrolyses heparan chain(2) TAS Homo sapiens 15377 R-HSA-2090043 https://reactome.org/PathwayBrowser/#/R-HSA-2090043 SGSH hydrolyses Heparan sulfate chain(7) TAS Homo sapiens 15377 R-HSA-2090079 https://reactome.org/PathwayBrowser/#/R-HSA-2090079 GLB1 hydrolyses linker chain(2) TAS Homo sapiens 15377 R-HSA-209055 https://reactome.org/PathwayBrowser/#/R-HSA-209055 PPM1A dephosphorylates nuclear SMAD2/3 TAS Homo sapiens 15377 R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 15377 R-HSA-209845 https://reactome.org/PathwayBrowser/#/R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D TAS Homo sapiens 15377 R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 15377 R-HSA-209891 https://reactome.org/PathwayBrowser/#/R-HSA-209891 Dopamine is oxidised to noradrenaline TAS Homo sapiens 15377 R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 15377 R-HSA-2105001 https://reactome.org/PathwayBrowser/#/R-HSA-2105001 HEXA cleaves the terminal GalNAc from DS TAS Homo sapiens 15377 R-HSA-211873 https://reactome.org/PathwayBrowser/#/R-HSA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 TAS Homo sapiens 15377 R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 15377 R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 15377 R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 15377 R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 15377 R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 15377 R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 15377 R-HSA-211923 https://reactome.org/PathwayBrowser/#/R-HSA-211923 CYP26C1 4-hydroxylates 9cRA TAS Homo sapiens 15377 R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 15377 R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 15377 R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 15377 R-HSA-211950 https://reactome.org/PathwayBrowser/#/R-HSA-211950 CYP24A1 24-hydroxylates CTL TAS Homo sapiens 15377 R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 15377 R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 15377 R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 15377 R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 15377 R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 15377 R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 15377 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 15377 R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 15377 R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 15377 R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 15377 R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 15377 R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 15377 R-HSA-2130725 https://reactome.org/PathwayBrowser/#/R-HSA-2130725 Internalization of MHC II:Ii clathrin coated vesicle TAS Homo sapiens 15377 R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 15377 R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 15377 R-HSA-2160492 https://reactome.org/PathwayBrowser/#/R-HSA-2160492 IL4I1:FAD oxidises L-Phe to kPPV TAS Homo sapiens 15377 R-HSA-2160874 https://reactome.org/PathwayBrowser/#/R-HSA-2160874 HYAL1 hydrolyses (HA)50 TAS Homo sapiens 15377 R-HSA-2161187 https://reactome.org/PathwayBrowser/#/R-HSA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine TAS Homo sapiens 15377 R-HSA-2161195 https://reactome.org/PathwayBrowser/#/R-HSA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine TAS Homo sapiens 15377 R-HSA-2161506 https://reactome.org/PathwayBrowser/#/R-HSA-2161506 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 15377 R-HSA-2161538 https://reactome.org/PathwayBrowser/#/R-HSA-2161538 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 15377 R-HSA-2161588 https://reactome.org/PathwayBrowser/#/R-HSA-2161588 Delta12-PGJ2 is dehydrated to 15d-PGJ2 TAS Homo sapiens 15377 R-HSA-2161619 https://reactome.org/PathwayBrowser/#/R-HSA-2161619 PGI2 is hydrolysed to 6k-PGF1a TAS Homo sapiens 15377 R-HSA-2161659 https://reactome.org/PathwayBrowser/#/R-HSA-2161659 PGE2 is dehydrated to PGA2 TAS Homo sapiens 15377 R-HSA-2161668 https://reactome.org/PathwayBrowser/#/R-HSA-2161668 PGA2 is dehydrated to 15d-PGA2 IEA Homo sapiens 15377 R-HSA-2161673 https://reactome.org/PathwayBrowser/#/R-HSA-2161673 PGD2 is dehydrated to 15d-PGD2 TAS Homo sapiens 15377 R-HSA-2161733 https://reactome.org/PathwayBrowser/#/R-HSA-2161733 PGD2 is dehydrated to PGJ2 TAS Homo sapiens 15377 R-HSA-2161745 https://reactome.org/PathwayBrowser/#/R-HSA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15377 R-HSA-2161791 https://reactome.org/PathwayBrowser/#/R-HSA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 TAS Homo sapiens 15377 R-HSA-2161792 https://reactome.org/PathwayBrowser/#/R-HSA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15377 R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) TAS Homo sapiens 15377 R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 15377 R-HSA-2161868 https://reactome.org/PathwayBrowser/#/R-HSA-2161868 EXD4 is converted to EXE4 by DPEP TAS Homo sapiens 15377 R-HSA-2161890 https://reactome.org/PathwayBrowser/#/R-HSA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) TAS Homo sapiens 15377 R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) TAS Homo sapiens 15377 R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 15377 R-HSA-2161946 https://reactome.org/PathwayBrowser/#/R-HSA-2161946 5S-HpETE is reduced to 5S-HETE by GPX1/2/4 IEA Homo sapiens 15377 R-HSA-2161949 https://reactome.org/PathwayBrowser/#/R-HSA-2161949 HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH TAS Homo sapiens 15377 R-HSA-2161951 https://reactome.org/PathwayBrowser/#/R-HSA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 TAS Homo sapiens 15377 R-HSA-2161959 https://reactome.org/PathwayBrowser/#/R-HSA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 TAS Homo sapiens 15377 R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 TAS Homo sapiens 15377 R-HSA-2161962 https://reactome.org/PathwayBrowser/#/R-HSA-2161962 LTA4 is hydrolysed to 6t-/6t,12epi-LTB4 TAS Homo sapiens 15377 R-HSA-2161979 https://reactome.org/PathwayBrowser/#/R-HSA-2161979 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH TAS Homo sapiens 15377 R-HSA-2161999 https://reactome.org/PathwayBrowser/#/R-HSA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 TAS Homo sapiens 15377 R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB IEA Homo sapiens 15377 R-HSA-2162191 https://reactome.org/PathwayBrowser/#/R-HSA-2162191 Unknown enzyme hydroxylates DMPhOH IEA Homo sapiens 15377 R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 15377 R-HSA-2162225 https://reactome.org/PathwayBrowser/#/R-HSA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments TAS Homo sapiens 15377 R-HSA-2162226 https://reactome.org/PathwayBrowser/#/R-HSA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc TAS Homo sapiens 15377 R-HSA-2162227 https://reactome.org/PathwayBrowser/#/R-HSA-2162227 GUSB tetramer hydrolyses (HA)2 TAS Homo sapiens 15377 R-HSA-216723 https://reactome.org/PathwayBrowser/#/R-HSA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 15377 R-HSA-216757 https://reactome.org/PathwayBrowser/#/R-HSA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane TAS Homo sapiens 15377 R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 15377 R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 15377 R-HSA-2179291 https://reactome.org/PathwayBrowser/#/R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 IEA Homo sapiens 15377 R-HSA-2187401 https://reactome.org/PathwayBrowser/#/R-HSA-2187401 MTMR4 dephosphorylates SMAD2/3 TAS Homo sapiens 15377 R-HSA-2206299 https://reactome.org/PathwayBrowser/#/R-HSA-2206299 Defective IDUA does not hydrolyse Heparan sulfate chain(6) TAS Homo sapiens 15377 R-HSA-2262743 https://reactome.org/PathwayBrowser/#/R-HSA-2262743 Defective IDS does not hydrolyse dermatan sulfate (Chebi:63517 chain) TAS Homo sapiens 15377 R-HSA-2263444 https://reactome.org/PathwayBrowser/#/R-HSA-2263444 Defective SGSH does not hydrolyse Heparan sulfate chain(7) TAS Homo sapiens 15377 R-HSA-2263490 https://reactome.org/PathwayBrowser/#/R-HSA-2263490 Defective GALNS does not hydrolyse sulfate from Gal6S in keratan sulfate TAS Homo sapiens 15377 R-HSA-2263495 https://reactome.org/PathwayBrowser/#/R-HSA-2263495 Defective GNS does not hydrolyse 6-sulfate from GlcNAc6S TAS Homo sapiens 15377 R-HSA-2263496 https://reactome.org/PathwayBrowser/#/R-HSA-2263496 Defective NAGLU does not hydrolyse Heparan sulfate chain(4) TAS Homo sapiens 15377 R-HSA-2265534 https://reactome.org/PathwayBrowser/#/R-HSA-2265534 Defective GLB1 does not hydrolyse a glycosaminoglycan TAS Homo sapiens 15377 R-HSA-2282889 https://reactome.org/PathwayBrowser/#/R-HSA-2282889 Defective ARSB does not hydrolyse C4S/C6S chains TAS Homo sapiens 15377 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 15377 R-HSA-2317387 https://reactome.org/PathwayBrowser/#/R-HSA-2317387 PTEN cancer mutants do not dephosphorylate PIP3 TAS Homo sapiens 15377 R-HSA-2318373 https://reactome.org/PathwayBrowser/#/R-HSA-2318373 Defective GUSB does not hydrolyse (HA)2 TAS Homo sapiens 15377 R-HSA-2318585 https://reactome.org/PathwayBrowser/#/R-HSA-2318585 Defective HYAL1 does not hydrolyse Chondroitin chains TAS Homo sapiens 15377 R-HSA-2393939 https://reactome.org/PathwayBrowser/#/R-HSA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 15377 R-HSA-2393954 https://reactome.org/PathwayBrowser/#/R-HSA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 15377 R-HSA-2395340 https://reactome.org/PathwayBrowser/#/R-HSA-2395340 Formation of hydroxyallysine by LOX TAS Homo sapiens 15377 R-HSA-2395818 https://reactome.org/PathwayBrowser/#/R-HSA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP TAS Homo sapiens 15377 R-HSA-2395849 https://reactome.org/PathwayBrowser/#/R-HSA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 15377 R-HSA-2395869 https://reactome.org/PathwayBrowser/#/R-HSA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 15377 R-HSA-2395872 https://reactome.org/PathwayBrowser/#/R-HSA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP TAS Homo sapiens 15377 R-HSA-2395873 https://reactome.org/PathwayBrowser/#/R-HSA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP TAS Homo sapiens 15377 R-HSA-2395876 https://reactome.org/PathwayBrowser/#/R-HSA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 15377 R-HSA-2395879 https://reactome.org/PathwayBrowser/#/R-HSA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 15377 R-HSA-2395965 https://reactome.org/PathwayBrowser/#/R-HSA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP TAS Homo sapiens 15377 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 15377 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 15377 R-HSA-2408530 https://reactome.org/PathwayBrowser/#/R-HSA-2408530 MeSeH is hydrolysed to H2Se by methylselenol demethylase IEA Homo sapiens 15377 R-HSA-2408532 https://reactome.org/PathwayBrowser/#/R-HSA-2408532 AdeSeHCys is hydrolysed to SeHCys by AHCY IEA Homo sapiens 15377 R-HSA-2408537 https://reactome.org/PathwayBrowser/#/R-HSA-2408537 Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH IEA Homo sapiens 15377 R-HSA-2408539 https://reactome.org/PathwayBrowser/#/R-HSA-2408539 MeSec is hydrolysed to MeSeH by PXLP-K212-CTH IEA Homo sapiens 15377 R-HSA-2408543 https://reactome.org/PathwayBrowser/#/R-HSA-2408543 SeCysta is hydrolysed to Sec by PXLP-K212-CTH IEA Homo sapiens 15377 R-HSA-2408548 https://reactome.org/PathwayBrowser/#/R-HSA-2408548 PAPSe is reduced to SeO3(2-) by PAPSe reductase IEA Homo sapiens 15377 R-HSA-2408551 https://reactome.org/PathwayBrowser/#/R-HSA-2408551 SeMet is converted to AdoSeMet by MAT TAS Homo sapiens 15377 R-HSA-2408555 https://reactome.org/PathwayBrowser/#/R-HSA-2408555 Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer TAS Homo sapiens 15377 R-HSA-2408556 https://reactome.org/PathwayBrowser/#/R-HSA-2408556 SeO3(2-) combines with GSH to form GSSeSG and GSSG IEA Homo sapiens 15377 R-HSA-2408558 https://reactome.org/PathwayBrowser/#/R-HSA-2408558 SeO3(2-) is reduced to H2Se by TXNRD1 IEA Homo sapiens 15377 R-HSA-2408559 https://reactome.org/PathwayBrowser/#/R-HSA-2408559 SeHCys and Ser are dehydrated into SeCysta by CBS IEA Homo sapiens 15377 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 15377 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 15377 R-HSA-2454118 https://reactome.org/PathwayBrowser/#/R-HSA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO TAS Homo sapiens 15377 R-HSA-2465924 https://reactome.org/PathwayBrowser/#/R-HSA-2465924 OPN1LW binds 11cRAL TAS Homo sapiens 15377 R-HSA-2465941 https://reactome.org/PathwayBrowser/#/R-HSA-2465941 A REH hydrolyses 11cRE to 11cROL IEA Homo sapiens 15377 R-HSA-2466085 https://reactome.org/PathwayBrowser/#/R-HSA-2466085 at-retinyl is hydrolysed from R* to release atRAL TAS Homo sapiens 15377 R-HSA-2466749 https://reactome.org/PathwayBrowser/#/R-HSA-2466749 ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol IEA Homo sapiens 15377 R-HSA-2466764 https://reactome.org/PathwayBrowser/#/R-HSA-2466764 NRPE condenses with atRAL to form A2PE TAS Homo sapiens 15377 R-HSA-2466802 https://reactome.org/PathwayBrowser/#/R-HSA-2466802 Defective ABCA4 does not transport NRPE from disc membranes TAS Homo sapiens 15377 R-HSA-2466831 https://reactome.org/PathwayBrowser/#/R-HSA-2466831 A2PE hydrolyses to A2E TAS Homo sapiens 15377 R-HSA-2509793 https://reactome.org/PathwayBrowser/#/R-HSA-2509793 NUDT16 hydrolyses dIDP to dIMP TAS Homo sapiens 15377 R-HSA-2509816 https://reactome.org/PathwayBrowser/#/R-HSA-2509816 NUDT16 hydrolyses IDP to IMP TAS Homo sapiens 15377 R-HSA-2509827 https://reactome.org/PathwayBrowser/#/R-HSA-2509827 ITPA hydrolyses ITP to IMP TAS Homo sapiens 15377 R-HSA-2509831 https://reactome.org/PathwayBrowser/#/R-HSA-2509831 ITPA hydrolyses XTP to XMP TAS Homo sapiens 15377 R-HSA-2509838 https://reactome.org/PathwayBrowser/#/R-HSA-2509838 ITPA hydrolyses dITP to dIMP TAS Homo sapiens 15377 R-HSA-2529015 https://reactome.org/PathwayBrowser/#/R-HSA-2529015 Dephosphorylation of CK2-modified condensin I TAS Homo sapiens 15377 R-HSA-2584246 https://reactome.org/PathwayBrowser/#/R-HSA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP TAS Homo sapiens 15377 R-HSA-2632521 https://reactome.org/PathwayBrowser/#/R-HSA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL TAS Homo sapiens 15377 R-HSA-265783 https://reactome.org/PathwayBrowser/#/R-HSA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-266012 https://reactome.org/PathwayBrowser/#/R-HSA-266012 LTD4 is converted to LTE4 by DPEP1/2 TAS Homo sapiens 15377 R-HSA-266046 https://reactome.org/PathwayBrowser/#/R-HSA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 TAS Homo sapiens 15377 R-HSA-266051 https://reactome.org/PathwayBrowser/#/R-HSA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 TAS Homo sapiens 15377 R-HSA-266072 https://reactome.org/PathwayBrowser/#/R-HSA-266072 LTA4 is hydolysed to LTB4 by LTA4H TAS Homo sapiens 15377 R-HSA-266082 https://reactome.org/PathwayBrowser/#/R-HSA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface TAS Homo sapiens 15377 R-HSA-2730847 https://reactome.org/PathwayBrowser/#/R-HSA-2730847 Hydrolysis of PIP2 by PLCG TAS Homo sapiens 15377 R-HSA-2730849 https://reactome.org/PathwayBrowser/#/R-HSA-2730849 Calcineurin binds and dephosphorylates NFAT TAS Homo sapiens 15377 R-HSA-2855047 https://reactome.org/PathwayBrowser/#/R-HSA-2855047 Hydrolysis of internal thioester in C4b TAS Homo sapiens 15377 R-HSA-2995330 https://reactome.org/PathwayBrowser/#/R-HSA-2995330 COX10 transforms heme to heme O TAS Homo sapiens 15377 R-HSA-2995334 https://reactome.org/PathwayBrowser/#/R-HSA-2995334 COX15 transforms heme O to heme A TAS Homo sapiens 15377 R-HSA-2995388 https://reactome.org/PathwayBrowser/#/R-HSA-2995388 PP2A dephosphorylates BANF1 TAS Homo sapiens 15377 R-HSA-3002811 https://reactome.org/PathwayBrowser/#/R-HSA-3002811 Myosin phosphatase dephosphorylates PLK1 TAS Homo sapiens 15377 R-HSA-3095901 https://reactome.org/PathwayBrowser/#/R-HSA-3095901 ABCC1 transports cytosolic RCbl to extracellular region TAS Homo sapiens 15377 R-HSA-3204311 https://reactome.org/PathwayBrowser/#/R-HSA-3204311 AOX1 oxidises PXL to PDXate TAS Homo sapiens 15377 R-HSA-3215295 https://reactome.org/PathwayBrowser/#/R-HSA-3215295 USP7 deubiquitinates MDM2 TAS Homo sapiens 15377 R-HSA-3215310 https://reactome.org/PathwayBrowser/#/R-HSA-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 TAS Homo sapiens 15377 R-HSA-3245943 https://reactome.org/PathwayBrowser/#/R-HSA-3245943 Viral DNA cleavage by TREX1 TAS Homo sapiens 15377 R-HSA-3247569 https://reactome.org/PathwayBrowser/#/R-HSA-3247569 PADI4 deiminates Histones TAS Homo sapiens 15377 R-HSA-3262512 https://reactome.org/PathwayBrowser/#/R-HSA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) TAS Homo sapiens 15377 R-HSA-3266566 https://reactome.org/PathwayBrowser/#/R-HSA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) TAS Homo sapiens 15377 R-HSA-3274540 https://reactome.org/PathwayBrowser/#/R-HSA-3274540 Defective G6PC does not hydrolyze glucose 6-phosphate TAS Homo sapiens 15377 R-HSA-3282876 https://reactome.org/PathwayBrowser/#/R-HSA-3282876 Defective G6PC3 does not hydrolyze glucose 6-phosphate TAS Homo sapiens 15377 R-HSA-3322995 https://reactome.org/PathwayBrowser/#/R-HSA-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O TAS Homo sapiens 15377 R-HSA-3323013 https://reactome.org/PathwayBrowser/#/R-HSA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 15377 R-HSA-3341277 https://reactome.org/PathwayBrowser/#/R-HSA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 15377 R-HSA-3341296 https://reactome.org/PathwayBrowser/#/R-HSA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) TAS Homo sapiens 15377 R-HSA-3341343 https://reactome.org/PathwayBrowser/#/R-HSA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O TAS Homo sapiens 15377 R-HSA-3341397 https://reactome.org/PathwayBrowser/#/R-HSA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 15377 R-HSA-3343700 https://reactome.org/PathwayBrowser/#/R-HSA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 15377 R-HSA-3371467 https://reactome.org/PathwayBrowser/#/R-HSA-3371467 SIRT1 deacetylates HSF1 TAS Homo sapiens 15377 R-HSA-350604 https://reactome.org/PathwayBrowser/#/R-HSA-350604 Agmatine + H2O <=> putrescine + urea TAS Homo sapiens 15377 R-HSA-350901 https://reactome.org/PathwayBrowser/#/R-HSA-350901 Iodide is organified TAS Homo sapiens 15377 R-HSA-3640872 https://reactome.org/PathwayBrowser/#/R-HSA-3640872 USP34 deubiquitinates AXIN1,AXIN2 TAS Homo sapiens 15377 R-HSA-3656259 https://reactome.org/PathwayBrowser/#/R-HSA-3656259 Defective HEXA does not cleave the terminal GalNAc from DS TAS Homo sapiens 15377 R-HSA-3662344 https://reactome.org/PathwayBrowser/#/R-HSA-3662344 Defective HEXB does not cleave the terminal GalNAc from DS TAS Homo sapiens 15377 R-HSA-3697838 https://reactome.org/PathwayBrowser/#/R-HSA-3697838 ATP7A transfers Cu from ATOX1 to SOD3 IEA Homo sapiens 15377 R-HSA-3697882 https://reactome.org/PathwayBrowser/#/R-HSA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN TAS Homo sapiens 15377 R-HSA-3697894 https://reactome.org/PathwayBrowser/#/R-HSA-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 TAS Homo sapiens 15377 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 15377 R-HSA-374909 https://reactome.org/PathwayBrowser/#/R-HSA-374909 Catabolism of Noradrenaline TAS Homo sapiens 15377 R-HSA-3769447 https://reactome.org/PathwayBrowser/#/R-HSA-3769447 HDAC1:2-containing complex deacetylate histones TAS Homo sapiens 15377 R-HSA-377643 https://reactome.org/PathwayBrowser/#/R-HSA-377643 Dephosphorylation of inactive SRC by PTPB1 TAS Homo sapiens 15377 R-HSA-3777129 https://reactome.org/PathwayBrowser/#/R-HSA-3777129 HDAC3 containing complexes deacetylate histone TAS Homo sapiens 15377 R-HSA-3781011 https://reactome.org/PathwayBrowser/#/R-HSA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 TAS Homo sapiens 15377 R-HSA-3781018 https://reactome.org/PathwayBrowser/#/R-HSA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 TAS Homo sapiens 15377 R-HSA-3782637 https://reactome.org/PathwayBrowser/#/R-HSA-3782637 HDAC8 deacetylates histones TAS Homo sapiens 15377 R-HSA-3782655 https://reactome.org/PathwayBrowser/#/R-HSA-3782655 HDAC10 deacetylates histone TAS Homo sapiens 15377 R-HSA-3791349 https://reactome.org/PathwayBrowser/#/R-HSA-3791349 Defective EPM2A does not dephosphorylate phosphoglycogen (type 2A disease) TAS Homo sapiens 15377 R-HSA-379382 https://reactome.org/PathwayBrowser/#/R-HSA-379382 MAOA:FAD deaminates DA to DOPAC TAS Homo sapiens 15377 R-HSA-379395 https://reactome.org/PathwayBrowser/#/R-HSA-379395 MAOA:FAD deaminates 3MT to HVA TAS Homo sapiens 15377 R-HSA-380949 https://reactome.org/PathwayBrowser/#/R-HSA-380949 AMPK is dephosphorylated TAS Homo sapiens 15377 R-HSA-382553 https://reactome.org/PathwayBrowser/#/R-HSA-382553 ABCA7:Apo1A-mediated phospholipid efflux TAS Homo sapiens 15377 R-HSA-382560 https://reactome.org/PathwayBrowser/#/R-HSA-382560 ABC7, mABC1 and mABC2 mediate heme transport TAS Homo sapiens 15377 R-HSA-382575 https://reactome.org/PathwayBrowser/#/R-HSA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix TAS Homo sapiens 15377 R-HSA-383190 https://reactome.org/PathwayBrowser/#/R-HSA-383190 HCO3- transport through ion channel TAS Homo sapiens 15377 R-HSA-389580 https://reactome.org/PathwayBrowser/#/R-HSA-389580 formyl-CoA + H2O => formate + CoASH TAS Homo sapiens 15377 R-HSA-389821 https://reactome.org/PathwayBrowser/#/R-HSA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ TAS Homo sapiens 15377 R-HSA-389862 https://reactome.org/PathwayBrowser/#/R-HSA-389862 Conversion of glyoxylate to oxalate TAS Homo sapiens 15377 R-HSA-389986 https://reactome.org/PathwayBrowser/#/R-HSA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA TAS Homo sapiens 15377 R-HSA-390252 https://reactome.org/PathwayBrowser/#/R-HSA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA TAS Homo sapiens 15377 R-HSA-390276 https://reactome.org/PathwayBrowser/#/R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA TAS Homo sapiens 15377 R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA TAS Homo sapiens 15377 R-HSA-390304 https://reactome.org/PathwayBrowser/#/R-HSA-390304 acetyl-CoA + H2O => acetate + CoASH TAS Homo sapiens 15377 R-HSA-390329 https://reactome.org/PathwayBrowser/#/R-HSA-390329 Dephosphorylation of AKT by PP2A TAS Homo sapiens 15377 R-HSA-399998 https://reactome.org/PathwayBrowser/#/R-HSA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate TAS Homo sapiens 15377 R-HSA-4084976 https://reactome.org/PathwayBrowser/#/R-HSA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P TAS Homo sapiens 15377 R-HSA-4084989 https://reactome.org/PathwayBrowser/#/R-HSA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac TAS Homo sapiens 15377 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 15377 R-HSA-4084999 https://reactome.org/PathwayBrowser/#/R-HSA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 15377 R-HSA-4085021 https://reactome.org/PathwayBrowser/#/R-HSA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP TAS Homo sapiens 15377 R-HSA-4085029 https://reactome.org/PathwayBrowser/#/R-HSA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 15377 R-HSA-4086392 https://reactome.org/PathwayBrowser/#/R-HSA-4086392 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 15377 R-HSA-4088141 https://reactome.org/PathwayBrowser/#/R-HSA-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 TAS Homo sapiens 15377 R-HSA-4088338 https://reactome.org/PathwayBrowser/#/R-HSA-4088338 Defective GNE does not hydrolyse UDP-GlcNAc TAS Homo sapiens 15377 R-HSA-4093339 https://reactome.org/PathwayBrowser/#/R-HSA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it TAS Homo sapiens 15377 R-HSA-416559 https://reactome.org/PathwayBrowser/#/R-HSA-416559 Inactivation of Rho-GTP by p190RhoGAP TAS Homo sapiens 15377 R-HSA-418553 https://reactome.org/PathwayBrowser/#/R-HSA-418553 cAMP degradation by Phosphodiesterases TAS Homo sapiens 15377 R-HSA-419232 https://reactome.org/PathwayBrowser/#/R-HSA-419232 Myosin phosphatase dephosphorylates myosin regulatory light chain IEA Homo sapiens 15377 R-HSA-426043 https://reactome.org/PathwayBrowser/#/R-HSA-426043 2-AG hydrolysis to arachidonate by MAGL TAS Homo sapiens 15377 R-HSA-428205 https://reactome.org/PathwayBrowser/#/R-HSA-428205 ACER2 hydrolyzes ceramide (Golgi) TAS Homo sapiens 15377 R-HSA-428231 https://reactome.org/PathwayBrowser/#/R-HSA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) TAS Homo sapiens 15377 R-HSA-428259 https://reactome.org/PathwayBrowser/#/R-HSA-428259 DEGS1 dehydrogenates dihydroceramide TAS Homo sapiens 15377 R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 15377 R-HSA-428262 https://reactome.org/PathwayBrowser/#/R-HSA-428262 ACER3 hydrolyzes phytoceramide TAS Homo sapiens 15377 R-HSA-428522 https://reactome.org/PathwayBrowser/#/R-HSA-428522 Inactivation of RAC1 IEA Homo sapiens 15377 R-HSA-428533 https://reactome.org/PathwayBrowser/#/R-HSA-428533 Inactivation of CDC42 IEA Homo sapiens 15377 R-HSA-428664 https://reactome.org/PathwayBrowser/#/R-HSA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates TAS Homo sapiens 15377 R-HSA-428690 https://reactome.org/PathwayBrowser/#/R-HSA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate TAS Homo sapiens 15377 R-HSA-428696 https://reactome.org/PathwayBrowser/#/R-HSA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate TAS Homo sapiens 15377 R-HSA-429157 https://reactome.org/PathwayBrowser/#/R-HSA-429157 ABCC4 accumulation of dense granule contents TAS Homo sapiens 15377 R-HSA-429730 https://reactome.org/PathwayBrowser/#/R-HSA-429730 PPM1L dephosphorylates multiphospho-CERT1-2 TAS Homo sapiens 15377 R-HSA-429845 https://reactome.org/PathwayBrowser/#/R-HSA-429845 5' to 3' exoribonuclease hydrolyzes decapped mRNA IEA Homo sapiens 15377 R-HSA-429860 https://reactome.org/PathwayBrowser/#/R-HSA-429860 DCP1-DCP2 complex decaps mRNA TAS Homo sapiens 15377 R-HSA-429955 https://reactome.org/PathwayBrowser/#/R-HSA-429955 CCR4-NOT complex deadenylates mRNA TAS Homo sapiens 15377 R-HSA-429961 https://reactome.org/PathwayBrowser/#/R-HSA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA TAS Homo sapiens 15377 R-HSA-429992 https://reactome.org/PathwayBrowser/#/R-HSA-429992 PARN deadenylates mRNA TAS Homo sapiens 15377 R-HSA-430021 https://reactome.org/PathwayBrowser/#/R-HSA-430021 PAN2-PAN3 complex partially deadenylates mRNA TAS Homo sapiens 15377 R-HSA-430028 https://reactome.org/PathwayBrowser/#/R-HSA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion TAS Homo sapiens 15377 R-HSA-432010 https://reactome.org/PathwayBrowser/#/R-HSA-432010 Aquaporin-1 passively transports water into cell TAS Homo sapiens 15377 R-HSA-432054 https://reactome.org/PathwayBrowser/#/R-HSA-432054 Aquaporin-1 passively transports water out of cell TAS Homo sapiens 15377 R-HSA-432065 https://reactome.org/PathwayBrowser/#/R-HSA-432065 p-S256-Aquaporin-2 passively transports water into cell TAS Homo sapiens 15377 R-HSA-432067 https://reactome.org/PathwayBrowser/#/R-HSA-432067 Aquaporin-4 passively transports water out of cell TAS Homo sapiens 15377 R-HSA-4341669 https://reactome.org/PathwayBrowser/#/R-HSA-4341669 Defective NEU1 does not hydrolyse Neu5Ac from glycoconjugates TAS Homo sapiens 15377 R-HSA-4419948 https://reactome.org/PathwayBrowser/#/R-HSA-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN TAS Homo sapiens 15377 R-HSA-4419986 https://reactome.org/PathwayBrowser/#/R-HSA-4419986 Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL TAS Homo sapiens 15377 R-HSA-443894 https://reactome.org/PathwayBrowser/#/R-HSA-443894 TXA2 is hydrolysed to TXB2 TAS Homo sapiens 15377 R-HSA-445714 https://reactome.org/PathwayBrowser/#/R-HSA-445714 Aquaporin-3 passively transports water out of cell TAS Homo sapiens 15377 R-HSA-446200 https://reactome.org/PathwayBrowser/#/R-HSA-446200 DOLPP1 dephosphorylates DOLDP to DOLP TAS Homo sapiens 15377 R-HSA-449937 https://reactome.org/PathwayBrowser/#/R-HSA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] TAS Homo sapiens 15377 R-HSA-452036 https://reactome.org/PathwayBrowser/#/R-HSA-452036 arginine + H2O => ornithine + urea [ARG2] TAS Homo sapiens 15377 R-HSA-4551451 https://reactome.org/PathwayBrowser/#/R-HSA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling TAS Homo sapiens 15377 R-HSA-4641236 https://reactome.org/PathwayBrowser/#/R-HSA-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling TAS Homo sapiens 15377 R-HSA-4793949 https://reactome.org/PathwayBrowser/#/R-HSA-4793949 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (a branch) TAS Homo sapiens 15377 R-HSA-504054 https://reactome.org/PathwayBrowser/#/R-HSA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] TAS Homo sapiens 15377 R-HSA-507868 https://reactome.org/PathwayBrowser/#/R-HSA-507868 Aquaporins passively transport water into cells TAS Homo sapiens 15377 R-HSA-507870 https://reactome.org/PathwayBrowser/#/R-HSA-507870 Aquaporins passively transport water out of cells TAS Homo sapiens 15377 R-HSA-508308 https://reactome.org/PathwayBrowser/#/R-HSA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] TAS Homo sapiens 15377 R-HSA-5220990 https://reactome.org/PathwayBrowser/#/R-HSA-5220990 TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine IEA Homo sapiens 15377 R-HSA-5221130 https://reactome.org/PathwayBrowser/#/R-HSA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol TAS Homo sapiens 15377 R-HSA-5223313 https://reactome.org/PathwayBrowser/#/R-HSA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) TAS Homo sapiens 15377 R-HSA-5223317 https://reactome.org/PathwayBrowser/#/R-HSA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen TAS Homo sapiens 15377 R-HSA-5251955 https://reactome.org/PathwayBrowser/#/R-HSA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm TAS Homo sapiens 15377 R-HSA-5251959 https://reactome.org/PathwayBrowser/#/R-HSA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol TAS Homo sapiens 15377 R-HSA-5251989 https://reactome.org/PathwayBrowser/#/R-HSA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol TAS Homo sapiens 15377 R-HSA-5263614 https://reactome.org/PathwayBrowser/#/R-HSA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 TAS Homo sapiens 15377 R-HSA-5263616 https://reactome.org/PathwayBrowser/#/R-HSA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 TAS Homo sapiens 15377 R-HSA-5333609 https://reactome.org/PathwayBrowser/#/R-HSA-5333609 MeSebGalNac is hydrolysed to MeSeH and bGalNac IEA Homo sapiens 15377 R-HSA-5333615 https://reactome.org/PathwayBrowser/#/R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC IEA Homo sapiens 15377 R-HSA-5362459 https://reactome.org/PathwayBrowser/#/R-HSA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol TAS Homo sapiens 15377 R-HSA-5362522 https://reactome.org/PathwayBrowser/#/R-HSA-5362522 ALDHs oxidise atRAL to atRA TAS Homo sapiens 15377 R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 15377 R-HSA-5387389 https://reactome.org/PathwayBrowser/#/R-HSA-5387389 Hh processing variants are translocated to the cytosol in a VCP-dependent manner TAS Homo sapiens 15377 R-HSA-5423647 https://reactome.org/PathwayBrowser/#/R-HSA-5423647 CYP2A13 oxidises AFM1 to AFM1E TAS Homo sapiens 15377 R-HSA-5423656 https://reactome.org/PathwayBrowser/#/R-HSA-5423656 AFXBO hydrolyses non-enzymatically to AFBDHD TAS Homo sapiens 15377 R-HSA-5423664 https://reactome.org/PathwayBrowser/#/R-HSA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 TAS Homo sapiens 15377 R-HSA-5423672 https://reactome.org/PathwayBrowser/#/R-HSA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO TAS Homo sapiens 15377 R-HSA-5423678 https://reactome.org/PathwayBrowser/#/R-HSA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 TAS Homo sapiens 15377 R-HSA-5423694 https://reactome.org/PathwayBrowser/#/R-HSA-5423694 AFBDHD hydrolyses non-enzymatically to AFBDHO TAS Homo sapiens 15377 R-HSA-5433072 https://reactome.org/PathwayBrowser/#/R-HSA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG TAS Homo sapiens 15377 R-HSA-5433074 https://reactome.org/PathwayBrowser/#/R-HSA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 15377 R-HSA-548843 https://reactome.org/PathwayBrowser/#/R-HSA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA TAS Homo sapiens 15377 R-HSA-5579081 https://reactome.org/PathwayBrowser/#/R-HSA-5579081 Defective ACY1 does not hydrolyse mercapturic acids TAS Homo sapiens 15377 R-HSA-5579084 https://reactome.org/PathwayBrowser/#/R-HSA-5579084 Defective AHCY does not hydrolyse AdoHcy TAS Homo sapiens 15377 R-HSA-5602295 https://reactome.org/PathwayBrowser/#/R-HSA-5602295 CYP4F22 20-hydroxylates TrXA3 TAS Homo sapiens 15377 R-HSA-5602984 https://reactome.org/PathwayBrowser/#/R-HSA-5602984 Defective GGT1 does not hydrolyse glutamate from AFXBO-SG, AFNBO-SG TAS Homo sapiens 15377 R-HSA-5603087 https://reactome.org/PathwayBrowser/#/R-HSA-5603087 Defective MAT1A does not transfer Ado from ATP to L-Met TAS Homo sapiens 15377 R-HSA-5603108 https://reactome.org/PathwayBrowser/#/R-HSA-5603108 Defective MAOA does not oxidatively deaminate 5HT TAS Homo sapiens 15377 R-HSA-5603114 https://reactome.org/PathwayBrowser/#/R-HSA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met TAS Homo sapiens 15377 R-HSA-5603208 https://reactome.org/PathwayBrowser/#/R-HSA-5603208 Defective OPLAH does not hydrolyse OPRO TAS Homo sapiens 15377 R-HSA-5607735 https://reactome.org/PathwayBrowser/#/R-HSA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 TAS Homo sapiens 15377 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 15377 R-HSA-5623513 https://reactome.org/PathwayBrowser/#/R-HSA-5623513 ASAP1 stimulates GTPase activity of ARF4 TAS Homo sapiens 15377 R-HSA-5628905 https://reactome.org/PathwayBrowser/#/R-HSA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate TAS Homo sapiens 15377 R-HSA-5631885 https://reactome.org/PathwayBrowser/#/R-HSA-5631885 PRDX1 overoxidizes TAS Homo sapiens 15377 R-HSA-5649705 https://reactome.org/PathwayBrowser/#/R-HSA-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) TAS Homo sapiens 15377 R-HSA-5651828 https://reactome.org/PathwayBrowser/#/R-HSA-5651828 PARG dePARylates PARP1,PARP2 TAS Homo sapiens 15377 R-HSA-5653770 https://reactome.org/PathwayBrowser/#/R-HSA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA TAS Homo sapiens 15377 R-HSA-5653786 https://reactome.org/PathwayBrowser/#/R-HSA-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA TAS Homo sapiens 15377 R-HSA-5655955 https://reactome.org/PathwayBrowser/#/R-HSA-5655955 OLAH hydrolyzes decanoyl-FASN dimer to DECA and FASN dimer IEA Homo sapiens 15377 R-HSA-5658001 https://reactome.org/PathwayBrowser/#/R-HSA-5658001 Defective LCT does not hydrolyze Lac TAS Homo sapiens 15377 R-HSA-5659861 https://reactome.org/PathwayBrowser/#/R-HSA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) TAS Homo sapiens 15377 R-HSA-5659879 https://reactome.org/PathwayBrowser/#/R-HSA-5659879 Defective SI does not hydrolyze iMal IEA Homo sapiens 15377 R-HSA-5659899 https://reactome.org/PathwayBrowser/#/R-HSA-5659899 Defective SI does not hydrolyze maltotriose IEA Homo sapiens 15377 R-HSA-5659922 https://reactome.org/PathwayBrowser/#/R-HSA-5659922 Defective SI does not hydrolyze Mal TAS Homo sapiens 15377 R-HSA-5659926 https://reactome.org/PathwayBrowser/#/R-HSA-5659926 Defective SI does not hydrolyze Suc IEA Homo sapiens 15377 R-HSA-5662692 https://reactome.org/PathwayBrowser/#/R-HSA-5662692 Dopa is oxidized to dopaquinone by TYR TAS Homo sapiens 15377 R-HSA-5665809 https://reactome.org/PathwayBrowser/#/R-HSA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments TAS Homo sapiens 15377 R-HSA-5672957 https://reactome.org/PathwayBrowser/#/R-HSA-5672957 PP2A dephosphorylates KSR1 TAS Homo sapiens 15377 R-HSA-5672961 https://reactome.org/PathwayBrowser/#/R-HSA-5672961 PP2A dephosphorylates inactive RAFs TAS Homo sapiens 15377 R-HSA-5675373 https://reactome.org/PathwayBrowser/#/R-HSA-5675373 Nuclear DUSPs dephosphorylate MAPKs TAS Homo sapiens 15377 R-HSA-5675376 https://reactome.org/PathwayBrowser/#/R-HSA-5675376 Cytosolic DUSPs dephosphorylate MAPKs TAS Homo sapiens 15377 R-HSA-5675431 https://reactome.org/PathwayBrowser/#/R-HSA-5675431 PP2A dephosphorylates RAF1 TAS Homo sapiens 15377 R-HSA-5675433 https://reactome.org/PathwayBrowser/#/R-HSA-5675433 PP5 dephosphorylates RAF1 S338 TAS Homo sapiens 15377 R-HSA-5676637 https://reactome.org/PathwayBrowser/#/R-HSA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA TAS Homo sapiens 15377 R-HSA-5676912 https://reactome.org/PathwayBrowser/#/R-HSA-5676912 Methionine is oxidised to methionine sulfoxide TAS Homo sapiens 15377 R-HSA-5676926 https://reactome.org/PathwayBrowser/#/R-HSA-5676926 Methionine sulfoxide is oxidised to methionine sulfone TAS Homo sapiens 15377 R-HSA-5678327 https://reactome.org/PathwayBrowser/#/R-HSA-5678327 MIOX oxidises Ins to GlcA TAS Homo sapiens 15377 R-HSA-5678517 https://reactome.org/PathwayBrowser/#/R-HSA-5678517 Defective ABCB11 does not transport bile salts from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-5678706 https://reactome.org/PathwayBrowser/#/R-HSA-5678706 ABCB4 transports PC from plasma membrane to extracellular region TAS Homo sapiens 15377 R-HSA-5678749 https://reactome.org/PathwayBrowser/#/R-HSA-5678749 Defective ABCB4 does not transport PC from plasma membrane to extracellular region TAS Homo sapiens 15377 R-HSA-5678822 https://reactome.org/PathwayBrowser/#/R-HSA-5678822 Defective CFTR does not transport Cl- from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-5678863 https://reactome.org/PathwayBrowser/#/R-HSA-5678863 CFTR transports Cl- from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-5678992 https://reactome.org/PathwayBrowser/#/R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-5679031 https://reactome.org/PathwayBrowser/#/R-HSA-5679031 Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-5679041 https://reactome.org/PathwayBrowser/#/R-HSA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-5679101 https://reactome.org/PathwayBrowser/#/R-HSA-5679101 Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-5679145 https://reactome.org/PathwayBrowser/#/R-HSA-5679145 Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-5682111 https://reactome.org/PathwayBrowser/#/R-HSA-5682111 Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 15377 R-HSA-5682285 https://reactome.org/PathwayBrowser/#/R-HSA-5682285 ABCA12 transports lipids from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-5682311 https://reactome.org/PathwayBrowser/#/R-HSA-5682311 Defective ABCA12 does not transport lipids from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-5683325 https://reactome.org/PathwayBrowser/#/R-HSA-5683325 Defective ABCD4:LMBRD1 does not transport Cbl from lysosomal lumen to cytosol TAS Homo sapiens 15377 R-HSA-5683355 https://reactome.org/PathwayBrowser/#/R-HSA-5683355 Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix TAS Homo sapiens 15377 R-HSA-5683405 https://reactome.org/PathwayBrowser/#/R-HSA-5683405 PPP5C dephosphorylates TP53BP1 TAS Homo sapiens 15377 R-HSA-5683672 https://reactome.org/PathwayBrowser/#/R-HSA-5683672 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body TAS Homo sapiens 15377 R-HSA-5683714 https://reactome.org/PathwayBrowser/#/R-HSA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body TAS Homo sapiens 15377 R-HSA-5683967 https://reactome.org/PathwayBrowser/#/R-HSA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX TAS Homo sapiens 15377 R-HSA-5684043 https://reactome.org/PathwayBrowser/#/R-HSA-5684043 Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix TAS Homo sapiens 15377 R-HSA-5684864 https://reactome.org/PathwayBrowser/#/R-HSA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB TAS Homo sapiens 15377 R-HSA-5685902 https://reactome.org/PathwayBrowser/#/R-HSA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC TAS Homo sapiens 15377 R-HSA-5685994 https://reactome.org/PathwayBrowser/#/R-HSA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 TAS Homo sapiens 15377 R-HSA-5686410 https://reactome.org/PathwayBrowser/#/R-HSA-5686410 BLM mediates dissolution of double Holliday junction TAS Homo sapiens 15377 R-HSA-5687464 https://reactome.org/PathwayBrowser/#/R-HSA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ TAS Homo sapiens 15377 R-HSA-5687664 https://reactome.org/PathwayBrowser/#/R-HSA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ TAS Homo sapiens 15377 R-HSA-5687758 https://reactome.org/PathwayBrowser/#/R-HSA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 TAS Homo sapiens 15377 R-HSA-5688397 https://reactome.org/PathwayBrowser/#/R-HSA-5688397 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body TAS Homo sapiens 15377 R-HSA-5688797 https://reactome.org/PathwayBrowser/#/R-HSA-5688797 ATXN3 family cleave Ub chains TAS Homo sapiens 15377 R-HSA-5688837 https://reactome.org/PathwayBrowser/#/R-HSA-5688837 ATXN3 deubiquitinates polyUb-PARK2 TAS Homo sapiens 15377 R-HSA-5689000 https://reactome.org/PathwayBrowser/#/R-HSA-5689000 AADAC deacetylates PHEN TAS Homo sapiens 15377 R-HSA-5689950 https://reactome.org/PathwayBrowser/#/R-HSA-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN TAS Homo sapiens 15377 R-HSA-5689972 https://reactome.org/PathwayBrowser/#/R-HSA-5689972 USP2 deubiquitinates MDM2,MDM4 TAS Homo sapiens 15377 R-HSA-5689973 https://reactome.org/PathwayBrowser/#/R-HSA-5689973 USP10,USP24,USP42 deubiquitinate TP53 TAS Homo sapiens 15377 R-HSA-5690042 https://reactome.org/PathwayBrowser/#/R-HSA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 15377 R-HSA-5690043 https://reactome.org/PathwayBrowser/#/R-HSA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 15377 R-HSA-5690046 https://reactome.org/PathwayBrowser/#/R-HSA-5690046 PPT2 hydrolyses PALMCoA to PALM TAS Homo sapiens 15377 R-HSA-5690066 https://reactome.org/PathwayBrowser/#/R-HSA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 15377 R-HSA-5690080 https://reactome.org/PathwayBrowser/#/R-HSA-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B TAS Homo sapiens 15377 R-HSA-5690152 https://reactome.org/PathwayBrowser/#/R-HSA-5690152 USP5 cleaves polyubiquitin TAS Homo sapiens 15377 R-HSA-5690157 https://reactome.org/PathwayBrowser/#/R-HSA-5690157 USP16,USP21 deubiquitinate Histone H2A TAS Homo sapiens 15377 R-HSA-5690159 https://reactome.org/PathwayBrowser/#/R-HSA-5690159 USP21 deubiquitinates RIPK1,DDX58 TAS Homo sapiens 15377 R-HSA-5690196 https://reactome.org/PathwayBrowser/#/R-HSA-5690196 USP8 deubiquitinates RNF128 TAS Homo sapiens 15377 R-HSA-5690319 https://reactome.org/PathwayBrowser/#/R-HSA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts TAS Homo sapiens 15377 R-HSA-5690340 https://reactome.org/PathwayBrowser/#/R-HSA-5690340 Defective ABCC6 does not transport organic anion from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-5690517 https://reactome.org/PathwayBrowser/#/R-HSA-5690517 PPT1 hydrolyses palmitoylated proteins TAS Homo sapiens 15377 R-HSA-5690565 https://reactome.org/PathwayBrowser/#/R-HSA-5690565 SCD desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15377 R-HSA-5690759 https://reactome.org/PathwayBrowser/#/R-HSA-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 TAS Homo sapiens 15377 R-HSA-5690790 https://reactome.org/PathwayBrowser/#/R-HSA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex TAS Homo sapiens 15377 R-HSA-5690808 https://reactome.org/PathwayBrowser/#/R-HSA-5690808 UCHL3, SENP8 cleave NEDD8 TAS Homo sapiens 15377 R-HSA-5690856 https://reactome.org/PathwayBrowser/#/R-HSA-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 TAS Homo sapiens 15377 R-HSA-5690870 https://reactome.org/PathwayBrowser/#/R-HSA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 TAS Homo sapiens 15377 R-HSA-5691381 https://reactome.org/PathwayBrowser/#/R-HSA-5691381 MYSM1 deubiquitinates Histone H2A TAS Homo sapiens 15377 R-HSA-5691411 https://reactome.org/PathwayBrowser/#/R-HSA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A TAS Homo sapiens 15377 R-HSA-5691439 https://reactome.org/PathwayBrowser/#/R-HSA-5691439 BRISC complex deubiquitinates NLRP3 TAS Homo sapiens 15377 R-HSA-5691507 https://reactome.org/PathwayBrowser/#/R-HSA-5691507 ASPA deacetylates NAA to acetate and L-aspartate TAS Homo sapiens 15377 R-HSA-5691512 https://reactome.org/PathwayBrowser/#/R-HSA-5691512 APEH hydrolyses NAc-Ser-protein TAS Homo sapiens 15377 R-HSA-5692261 https://reactome.org/PathwayBrowser/#/R-HSA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM TAS Homo sapiens 15377 R-HSA-5692283 https://reactome.org/PathwayBrowser/#/R-HSA-5692283 ALD3A1 oxidises 4HPCP to CXPA TAS Homo sapiens 15377 R-HSA-5692462 https://reactome.org/PathwayBrowser/#/R-HSA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen TAS Homo sapiens 15377 R-HSA-5692480 https://reactome.org/PathwayBrowser/#/R-HSA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen TAS Homo sapiens 15377 R-HSA-5692754 https://reactome.org/PathwayBrowser/#/R-HSA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 TAS Homo sapiens 15377 R-HSA-5693092 https://reactome.org/PathwayBrowser/#/R-HSA-5693092 Unknown deacetylase deacetylates 7K-BACE1(46-501) TAS Homo sapiens 15377 R-HSA-5693153 https://reactome.org/PathwayBrowser/#/R-HSA-5693153 PPM1K dephosphorylates p-BCKDH TAS Homo sapiens 15377 R-HSA-5693346 https://reactome.org/PathwayBrowser/#/R-HSA-5693346 CECRI deaminates Ade-Rib to Ino TAS Homo sapiens 15377 R-HSA-5693373 https://reactome.org/PathwayBrowser/#/R-HSA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit TAS Homo sapiens 15377 R-HSA-5693589 https://reactome.org/PathwayBrowser/#/R-HSA-5693589 D-loop dissociation and strand annealing TAS Homo sapiens 15377 R-HSA-5693608 https://reactome.org/PathwayBrowser/#/R-HSA-5693608 Initial resection of double-strand break ends TAS Homo sapiens 15377 R-HSA-5693691 https://reactome.org/PathwayBrowser/#/R-HSA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG TAS Homo sapiens 15377 R-HSA-5693724 https://reactome.org/PathwayBrowser/#/R-HSA-5693724 ESD dimer hydrolyses S-FGSH to GSH TAS Homo sapiens 15377 R-HSA-5693742 https://reactome.org/PathwayBrowser/#/R-HSA-5693742 FAAH hydrolyses AEA to AA and ETA TAS Homo sapiens 15377 R-HSA-5693751 https://reactome.org/PathwayBrowser/#/R-HSA-5693751 FAAH2 hydrolyses AEA to AA and ETA TAS Homo sapiens 15377 R-HSA-5693761 https://reactome.org/PathwayBrowser/#/R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids TAS Homo sapiens 15377 R-HSA-5693807 https://reactome.org/PathwayBrowser/#/R-HSA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc TAS Homo sapiens 15377 R-HSA-5694077 https://reactome.org/PathwayBrowser/#/R-HSA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD TAS Homo sapiens 15377 R-HSA-5694109 https://reactome.org/PathwayBrowser/#/R-HSA-5694109 LIPC dimer hydrolyses TAG to DAG and FA TAS Homo sapiens 15377 R-HSA-5694126 https://reactome.org/PathwayBrowser/#/R-HSA-5694126 NT5C3B hydrolyses 7MGP to 7MG TAS Homo sapiens 15377 R-HSA-5694137 https://reactome.org/PathwayBrowser/#/R-HSA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser TAS Homo sapiens 15377 R-HSA-5694421 https://reactome.org/PathwayBrowser/#/R-HSA-5694421 PP6 dephosphorylates SEC24 TAS Homo sapiens 15377 R-HSA-5694462 https://reactome.org/PathwayBrowser/#/R-HSA-5694462 ABHD6,12 hydrolyse 3AG TAS Homo sapiens 15377 R-HSA-5694485 https://reactome.org/PathwayBrowser/#/R-HSA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC TAS Homo sapiens 15377 R-HSA-5694563 https://reactome.org/PathwayBrowser/#/R-HSA-5694563 ABHD10 hydrolyses MPAG TAS Homo sapiens 15377 R-HSA-5694583 https://reactome.org/PathwayBrowser/#/R-HSA-5694583 ABHD4 hydrolyses NAPE TAS Homo sapiens 15377 R-HSA-5695964 https://reactome.org/PathwayBrowser/#/R-HSA-5695964 ABHD14B hydrolyses PNPB TAS Homo sapiens 15377 R-HSA-5696049 https://reactome.org/PathwayBrowser/#/R-HSA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 15377 R-HSA-5696080 https://reactome.org/PathwayBrowser/#/R-HSA-5696080 ALDH3B1 oxidises HXAL to PALM TAS Homo sapiens 15377 R-HSA-5696091 https://reactome.org/PathwayBrowser/#/R-HSA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH TAS Homo sapiens 15377 R-HSA-5696101 https://reactome.org/PathwayBrowser/#/R-HSA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA TAS Homo sapiens 15377 R-HSA-5696119 https://reactome.org/PathwayBrowser/#/R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol TAS Homo sapiens 15377 R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 15377 R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 15377 R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 15377 R-HSA-5696197 https://reactome.org/PathwayBrowser/#/R-HSA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP TAS Homo sapiens 15377 R-HSA-5696230 https://reactome.org/PathwayBrowser/#/R-HSA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite TAS Homo sapiens 15377 R-HSA-5696365 https://reactome.org/PathwayBrowser/#/R-HSA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe TAS Homo sapiens 15377 R-HSA-5696408 https://reactome.org/PathwayBrowser/#/R-HSA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL TAS Homo sapiens 15377 R-HSA-5696415 https://reactome.org/PathwayBrowser/#/R-HSA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA TAS Homo sapiens 15377 R-HSA-5696465 https://reactome.org/PathwayBrowser/#/R-HSA-5696465 USP45 deubiquitinates ERCC1 TAS Homo sapiens 15377 R-HSA-5696534 https://reactome.org/PathwayBrowser/#/R-HSA-5696534 USP18 deubiquitinates TAK1:TAB1 TAS Homo sapiens 15377 R-HSA-5696564 https://reactome.org/PathwayBrowser/#/R-HSA-5696564 USP25 deubiquitinates DDX58 TAS Homo sapiens 15377 R-HSA-5696600 https://reactome.org/PathwayBrowser/#/R-HSA-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 TAS Homo sapiens 15377 R-HSA-5696605 https://reactome.org/PathwayBrowser/#/R-HSA-5696605 USP12, USP26 deubiquitinate AR TAS Homo sapiens 15377 R-HSA-5696627 https://reactome.org/PathwayBrowser/#/R-HSA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG TAS Homo sapiens 15377 R-HSA-5696872 https://reactome.org/PathwayBrowser/#/R-HSA-5696872 USP30 deubiquitinates Ub-MOM proteins TAS Homo sapiens 15377 R-HSA-5696914 https://reactome.org/PathwayBrowser/#/R-HSA-5696914 USP28 deubiquitinates CLSPN and MYC TAS Homo sapiens 15377 R-HSA-5696945 https://reactome.org/PathwayBrowser/#/R-HSA-5696945 USP33 deubiquitinates CCP110,ARRB TAS Homo sapiens 15377 R-HSA-5696947 https://reactome.org/PathwayBrowser/#/R-HSA-5696947 USP47 deubiquitinates POLB TAS Homo sapiens 15377 R-HSA-5696958 https://reactome.org/PathwayBrowser/#/R-HSA-5696958 USP44 deubiquitinates CDC20 TAS Homo sapiens 15377 R-HSA-5696960 https://reactome.org/PathwayBrowser/#/R-HSA-5696960 USP49 deubiquitinates H2B TAS Homo sapiens 15377 R-HSA-5696968 https://reactome.org/PathwayBrowser/#/R-HSA-5696968 USP20, USP33 deubiquitinate ADRB2 TAS Homo sapiens 15377 R-HSA-5696997 https://reactome.org/PathwayBrowser/#/R-HSA-5696997 USP24 deubiquitinates DDB2 TAS Homo sapiens 15377 R-HSA-5697009 https://reactome.org/PathwayBrowser/#/R-HSA-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 TAS Homo sapiens 15377 R-HSA-622382 https://reactome.org/PathwayBrowser/#/R-HSA-622382 PIP2 hydrolysis IEA Homo sapiens 15377 R-HSA-6781764 https://reactome.org/PathwayBrowser/#/R-HSA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 TAS Homo sapiens 15377 R-HSA-6781779 https://reactome.org/PathwayBrowser/#/R-HSA-6781779 USP13 deubiquitinates BECN1,USP10 TAS Homo sapiens 15377 R-HSA-6781814 https://reactome.org/PathwayBrowser/#/R-HSA-6781814 USP19 deubiquitinates RNF123 TAS Homo sapiens 15377 R-HSA-6781897 https://reactome.org/PathwayBrowser/#/R-HSA-6781897 USP11 deubiquitinates NFKBIA TAS Homo sapiens 15377 R-HSA-6782069 https://reactome.org/PathwayBrowser/#/R-HSA-6782069 UVSSA:USP7 deubiquitinates ERCC6 TAS Homo sapiens 15377 R-HSA-6782106 https://reactome.org/PathwayBrowser/#/R-HSA-6782106 USP10 deubiquitinates SNX3, CFTR TAS Homo sapiens 15377 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 15377 R-HSA-6782336 https://reactome.org/PathwayBrowser/#/R-HSA-6782336 ADAT1 deaminates adenosine-37 in tRNA(Ala) IEA Homo sapiens 15377 R-HSA-6782628 https://reactome.org/PathwayBrowser/#/R-HSA-6782628 USP8 deubiquitinates STAM2:HGS TAS Homo sapiens 15377 R-HSA-6782685 https://reactome.org/PathwayBrowser/#/R-HSA-6782685 EDEM1,3 hydrolyse (GlcNAc)2 (Man)8b to (GlcNAc)2 (Man)5 TAS Homo sapiens 15377 R-HSA-6782820 https://reactome.org/PathwayBrowser/#/R-HSA-6782820 USP17 deubiquitinates SUDS3 TAS Homo sapiens 15377 R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 15377 R-HSA-6783177 https://reactome.org/PathwayBrowser/#/R-HSA-6783177 USP21 deubiquitinates GATA3,IL33 TAS Homo sapiens 15377 R-HSA-6783221 https://reactome.org/PathwayBrowser/#/R-HSA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT TAS Homo sapiens 15377 R-HSA-6784402 https://reactome.org/PathwayBrowser/#/R-HSA-6784402 Spontaneous hydrolysis of 1-pyrroline-3-hydroxy-5-carboxylate to 4-OH-L-glutamate semialdehyde TAS Homo sapiens 15377 R-HSA-6784959 https://reactome.org/PathwayBrowser/#/R-HSA-6784959 BPHL hydrolyses VACV to ACV TAS Homo sapiens 15377 R-HSA-6786190 https://reactome.org/PathwayBrowser/#/R-HSA-6786190 CMBL hydrolyses OM to OLMS TAS Homo sapiens 15377 R-HSA-6786239 https://reactome.org/PathwayBrowser/#/R-HSA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE TAS Homo sapiens 15377 R-HSA-6786257 https://reactome.org/PathwayBrowser/#/R-HSA-6786257 DCTPP1 hydrolyses 5idCTP IEA Homo sapiens 15377 R-HSA-6786421 https://reactome.org/PathwayBrowser/#/R-HSA-6786421 CHIA hydrolyses chitin TAS Homo sapiens 15377 R-HSA-6786650 https://reactome.org/PathwayBrowser/#/R-HSA-6786650 DDHD1,2 hydrolyse PA TAS Homo sapiens 15377 R-HSA-6786652 https://reactome.org/PathwayBrowser/#/R-HSA-6786652 CHIT1 hydrolyses CHIT to 3xADGP TAS Homo sapiens 15377 R-HSA-6787632 https://reactome.org/PathwayBrowser/#/R-HSA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan TAS Homo sapiens 15377 R-HSA-6788295 https://reactome.org/PathwayBrowser/#/R-HSA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP TAS Homo sapiens 15377 R-HSA-6788912 https://reactome.org/PathwayBrowser/#/R-HSA-6788912 LHPP:Mg2+ dimer hydrolyses PPi TAS Homo sapiens 15377 R-HSA-6788974 https://reactome.org/PathwayBrowser/#/R-HSA-6788974 Hypochlorous acid and nitrite react to nitryl chloride (NO2Cl) TAS Homo sapiens 15377 R-HSA-6789031 https://reactome.org/PathwayBrowser/#/R-HSA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 15377 R-HSA-6789042 https://reactome.org/PathwayBrowser/#/R-HSA-6789042 Hydroxyl-initiated lipid peroxidation TAS Homo sapiens 15377 R-HSA-6789114 https://reactome.org/PathwayBrowser/#/R-HSA-6789114 Hydroxyl radical reacts with the base and sugar moiety of DNA TAS Homo sapiens 15377 R-HSA-6789126 https://reactome.org/PathwayBrowser/#/R-HSA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 15377 R-HSA-6789185 https://reactome.org/PathwayBrowser/#/R-HSA-6789185 Chloride ion and N-acyl group react to chloramide TAS Homo sapiens 15377 R-HSA-6789218 https://reactome.org/PathwayBrowser/#/R-HSA-6789218 Hypochlorous acid (HOCl) reacts with unsaturated lipid to form lipid chlorohydrins TAS Homo sapiens 15377 R-HSA-6789310 https://reactome.org/PathwayBrowser/#/R-HSA-6789310 LIPs hydrolyse TG to DAG and RCOOH TAS Homo sapiens 15377 R-HSA-6792445 https://reactome.org/PathwayBrowser/#/R-HSA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA TAS Homo sapiens 15377 R-HSA-6792863 https://reactome.org/PathwayBrowser/#/R-HSA-6792863 PP2A-PP2R5C dephosphorylates MDM2 TAS Homo sapiens 15377 R-HSA-6797627 https://reactome.org/PathwayBrowser/#/R-HSA-6797627 ASPG hydrolyses L-Asn to L-Asp TAS Homo sapiens 15377 R-HSA-6797630 https://reactome.org/PathwayBrowser/#/R-HSA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA TAS Homo sapiens 15377 R-HSA-6797653 https://reactome.org/PathwayBrowser/#/R-HSA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC TAS Homo sapiens 15377 R-HSA-6797913 https://reactome.org/PathwayBrowser/#/R-HSA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly TAS Homo sapiens 15377 R-HSA-6797955 https://reactome.org/PathwayBrowser/#/R-HSA-6797955 ALDH7A1 oxidises BETALD to BET TAS Homo sapiens 15377 R-HSA-6799545 https://reactome.org/PathwayBrowser/#/R-HSA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 TAS Homo sapiens 15377 R-HSA-6799581 https://reactome.org/PathwayBrowser/#/R-HSA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man TAS Homo sapiens 15377 R-HSA-6799604 https://reactome.org/PathwayBrowser/#/R-HSA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P TAS Homo sapiens 15377 R-HSA-6799695 https://reactome.org/PathwayBrowser/#/R-HSA-6799695 GPX5,6 reduce H2O2 to H2O TAS Homo sapiens 15377 R-HSA-6799977 https://reactome.org/PathwayBrowser/#/R-HSA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan TAS Homo sapiens 15377 R-HSA-6800198 https://reactome.org/PathwayBrowser/#/R-HSA-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer TAS Homo sapiens 15377 R-HSA-6800200 https://reactome.org/PathwayBrowser/#/R-HSA-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer TAS Homo sapiens 15377 R-HSA-6800299 https://reactome.org/PathwayBrowser/#/R-HSA-6800299 HGFAC cleaves pro-HGF to form HGF dimer TAS Homo sapiens 15377 R-HSA-6801462 https://reactome.org/PathwayBrowser/#/R-HSA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF TAS Homo sapiens 15377 R-HSA-6803545 https://reactome.org/PathwayBrowser/#/R-HSA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen TAS Homo sapiens 15377 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 15377 R-HSA-6803789 https://reactome.org/PathwayBrowser/#/R-HSA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA TAS Homo sapiens 15377 R-HSA-6803999 https://reactome.org/PathwayBrowser/#/R-HSA-6803999 HNO2 produces N2O3 TAS Homo sapiens 15377 R-HSA-6805650 https://reactome.org/PathwayBrowser/#/R-HSA-6805650 MTA2-NuRD complex deacetylates TP53 TAS Homo sapiens 15377 R-HSA-6807008 https://reactome.org/PathwayBrowser/#/R-HSA-6807008 PTPRJ dephosphorylates MET TAS Homo sapiens 15377 R-HSA-6807027 https://reactome.org/PathwayBrowser/#/R-HSA-6807027 PTPN1 and PTPN2 dephosphorylate MET TAS Homo sapiens 15377 R-HSA-6807053 https://reactome.org/PathwayBrowser/#/R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL TAS Homo sapiens 15377 R-HSA-6807118 https://reactome.org/PathwayBrowser/#/R-HSA-6807118 USP7 deubiquitinates monoubiquitinated PTEN TAS Homo sapiens 15377 R-HSA-6807206 https://reactome.org/PathwayBrowser/#/R-HSA-6807206 USP13 and OTUD3 deubiquitinate PTEN TAS Homo sapiens 15377 R-HSA-6807214 https://reactome.org/PathwayBrowser/#/R-HSA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) TAS Homo sapiens 15377 R-HSA-6808464 https://reactome.org/PathwayBrowser/#/R-HSA-6808464 ALDH3B2 oxidises HXAL to PALM TAS Homo sapiens 15377 R-HSA-6808487 https://reactome.org/PathwayBrowser/#/R-HSA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 15377 R-HSA-6808496 https://reactome.org/PathwayBrowser/#/R-HSA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 15377 R-HSA-6809263 https://reactome.org/PathwayBrowser/#/R-HSA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA TAS Homo sapiens 15377 R-HSA-6809287 https://reactome.org/PathwayBrowser/#/R-HSA-6809287 NUDT12 hydrolyses NADH to NMNH TAS Homo sapiens 15377 R-HSA-6809320 https://reactome.org/PathwayBrowser/#/R-HSA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane TAS Homo sapiens 15377 R-HSA-6809325 https://reactome.org/PathwayBrowser/#/R-HSA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane TAS Homo sapiens 15377 R-HSA-6809354 https://reactome.org/PathwayBrowser/#/R-HSA-6809354 NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT IEA Homo sapiens 15377 R-HSA-6809561 https://reactome.org/PathwayBrowser/#/R-HSA-6809561 I(1,3)P2 is dephosphorylated into I1P by MTMR7 IEA Homo sapiens 15377 R-HSA-6809565 https://reactome.org/PathwayBrowser/#/R-HSA-6809565 I(1,3)P2 is dephosphorylated into I1P by MTMR7:MTMR9 IEA Homo sapiens 15377 R-HSA-6809720 https://reactome.org/PathwayBrowser/#/R-HSA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 TAS Homo sapiens 15377 R-HSA-6809777 https://reactome.org/PathwayBrowser/#/R-HSA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 TAS Homo sapiens 15377 R-HSA-6809778 https://reactome.org/PathwayBrowser/#/R-HSA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 TAS Homo sapiens 15377 R-HSA-6809944 https://reactome.org/PathwayBrowser/#/R-HSA-6809944 PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane IEA Homo sapiens 15377 R-HSA-6809975 https://reactome.org/PathwayBrowser/#/R-HSA-6809975 PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane IEA Homo sapiens 15377 R-HSA-6810076 https://reactome.org/PathwayBrowser/#/R-HSA-6810076 DDO oxidizes D-Asp to OA TAS Homo sapiens 15377 R-HSA-6810410 https://reactome.org/PathwayBrowser/#/R-HSA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus TAS Homo sapiens 15377 R-HSA-6810464 https://reactome.org/PathwayBrowser/#/R-HSA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP TAS Homo sapiens 15377 R-HSA-6810472 https://reactome.org/PathwayBrowser/#/R-HSA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP TAS Homo sapiens 15377 R-HSA-6810474 https://reactome.org/PathwayBrowser/#/R-HSA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT TAS Homo sapiens 15377 R-HSA-6811504 https://reactome.org/PathwayBrowser/#/R-HSA-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma TAS Homo sapiens 15377 R-HSA-6813720 https://reactome.org/PathwayBrowser/#/R-HSA-6813720 NCEH1 hydrolyzes cholesterol esters TAS Homo sapiens 15377 R-HSA-6813740 https://reactome.org/PathwayBrowser/#/R-HSA-6813740 GDE1 hydrolyzes GroPIns TAS Homo sapiens 15377 R-HSA-6813749 https://reactome.org/PathwayBrowser/#/R-HSA-6813749 ALDH1A1 oxidises GA to DGA TAS Homo sapiens 15377 R-HSA-6814132 https://reactome.org/PathwayBrowser/#/R-HSA-6814132 GDPD5 hydrolyzes GPCho IEA Homo sapiens 15377 R-HSA-6814254 https://reactome.org/PathwayBrowser/#/R-HSA-6814254 PNPLA6 hydrolyzes LysoPtdCho TAS Homo sapiens 15377 R-HSA-6814766 https://reactome.org/PathwayBrowser/#/R-HSA-6814766 GDPD1 hydrolyzes LysoPtdCho IEA Homo sapiens 15377 R-HSA-6814778 https://reactome.org/PathwayBrowser/#/R-HSA-6814778 GDPD3 hydrolyzes LysoPtdCho IEA Homo sapiens 15377 R-HSA-6814797 https://reactome.org/PathwayBrowser/#/R-HSA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine TAS Homo sapiens 15377 R-HSA-69199 https://reactome.org/PathwayBrowser/#/R-HSA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A TAS Homo sapiens 15377 R-HSA-70262 https://reactome.org/PathwayBrowser/#/R-HSA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate TAS Homo sapiens 15377 R-HSA-70479 https://reactome.org/PathwayBrowser/#/R-HSA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P TAS Homo sapiens 15377 R-HSA-70494 https://reactome.org/PathwayBrowser/#/R-HSA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG TAS Homo sapiens 15377 R-HSA-70569 https://reactome.org/PathwayBrowser/#/R-HSA-70569 arginine + H2O => ornithine + urea [ARG1] TAS Homo sapiens 15377 R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] TAS Homo sapiens 15377 R-HSA-70599 https://reactome.org/PathwayBrowser/#/R-HSA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] TAS Homo sapiens 15377 R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] TAS Homo sapiens 15377 R-HSA-70609 https://reactome.org/PathwayBrowser/#/R-HSA-70609 glutamine + H2O => glutamate + NH4+ [GLS] TAS Homo sapiens 15377 R-HSA-70655 https://reactome.org/PathwayBrowser/#/R-HSA-70655 L-glutamate gamma-semialdehyde <=> L-1-pyrroline-5-carboxylate TAS Homo sapiens 15377 R-HSA-70667 https://reactome.org/PathwayBrowser/#/R-HSA-70667 1PYR-5COOH spontaneously hydrolyses to L-GluSS TAS Homo sapiens 15377 R-HSA-70679 https://reactome.org/PathwayBrowser/#/R-HSA-70679 ALDH4A1 oxidises L-GluSS to Glu TAS Homo sapiens 15377 R-HSA-70785 https://reactome.org/PathwayBrowser/#/R-HSA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA TAS Homo sapiens 15377 R-HSA-70830 https://reactome.org/PathwayBrowser/#/R-HSA-70830 tiglyl-CoA + H2O <=> alpha-methyl-beta-hydroxybutyryl-CoA TAS Homo sapiens 15377 R-HSA-70870 https://reactome.org/PathwayBrowser/#/R-HSA-70870 ECHS1 hydrates methacrylyl-CoA TAS Homo sapiens 15377 R-HSA-70881 https://reactome.org/PathwayBrowser/#/R-HSA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA TAS Homo sapiens 15377 R-HSA-70903 https://reactome.org/PathwayBrowser/#/R-HSA-70903 urocanate + H2O => 4-imidazolone-5-propionate TAS Homo sapiens 15377 R-HSA-70906 https://reactome.org/PathwayBrowser/#/R-HSA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ TAS Homo sapiens 15377 R-HSA-70938 https://reactome.org/PathwayBrowser/#/R-HSA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O TAS Homo sapiens 15377 R-HSA-70940 https://reactome.org/PathwayBrowser/#/R-HSA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ TAS Homo sapiens 15377 R-HSA-70941 https://reactome.org/PathwayBrowser/#/R-HSA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ TAS Homo sapiens 15377 R-HSA-70975 https://reactome.org/PathwayBrowser/#/R-HSA-70975 CS acetylates OA to citrate TAS Homo sapiens 15377 R-HSA-70982 https://reactome.org/PathwayBrowser/#/R-HSA-70982 FH tetramer hydrates fumarate to L-malate TAS Homo sapiens 15377 R-HSA-71146 https://reactome.org/PathwayBrowser/#/R-HSA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O TAS Homo sapiens 15377 R-HSA-71181 https://reactome.org/PathwayBrowser/#/R-HSA-71181 FAH cleaves 4FAA TAS Homo sapiens 15377 R-HSA-71189 https://reactome.org/PathwayBrowser/#/R-HSA-71189 AFMID hydrolyses NFK to L-KYN IEA Homo sapiens 15377 R-HSA-71200 https://reactome.org/PathwayBrowser/#/R-HSA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O TAS Homo sapiens 15377 R-HSA-71217 https://reactome.org/PathwayBrowser/#/R-HSA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine TAS Homo sapiens 15377 R-HSA-71239 https://reactome.org/PathwayBrowser/#/R-HSA-71239 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ IEA Homo sapiens 15377 R-HSA-71260 https://reactome.org/PathwayBrowser/#/R-HSA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT TAS Homo sapiens 15377 R-HSA-71287 https://reactome.org/PathwayBrowser/#/R-HSA-71287 phosphocreatine + H2O => creatinine + orthophosphate TAS Homo sapiens 15377 R-HSA-71296 https://reactome.org/PathwayBrowser/#/R-HSA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate TAS Homo sapiens 15377 R-HSA-71660 https://reactome.org/PathwayBrowser/#/R-HSA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O TAS Homo sapiens 15377 R-HSA-71676 https://reactome.org/PathwayBrowser/#/R-HSA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O TAS Homo sapiens 15377 R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 15377 R-HSA-71723 https://reactome.org/PathwayBrowser/#/R-HSA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] TAS Homo sapiens 15377 R-HSA-71732 https://reactome.org/PathwayBrowser/#/R-HSA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate TAS Homo sapiens 15377 R-HSA-71825 https://reactome.org/PathwayBrowser/#/R-HSA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) TAS Homo sapiens 15377 R-HSA-73571 https://reactome.org/PathwayBrowser/#/R-HSA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO TAS Homo sapiens 15377 R-HSA-73577 https://reactome.org/PathwayBrowser/#/R-HSA-73577 CAD hexamer transforms L-Gln to CAP TAS Homo sapiens 15377 R-HSA-73589 https://reactome.org/PathwayBrowser/#/R-HSA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate TAS Homo sapiens 15377 R-HSA-73591 https://reactome.org/PathwayBrowser/#/R-HSA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 TAS Homo sapiens 15377 R-HSA-73596 https://reactome.org/PathwayBrowser/#/R-HSA-73596 dCMP + H2O => dUMP + NH4+ TAS Homo sapiens 15377 R-HSA-73608 https://reactome.org/PathwayBrowser/#/R-HSA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) TAS Homo sapiens 15377 R-HSA-73618 https://reactome.org/PathwayBrowser/#/R-HSA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate TAS Homo sapiens 15377 R-HSA-73620 https://reactome.org/PathwayBrowser/#/R-HSA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 TAS Homo sapiens 15377 R-HSA-73647 https://reactome.org/PathwayBrowser/#/R-HSA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] TAS Homo sapiens 15377 R-HSA-73666 https://reactome.org/PathwayBrowser/#/R-HSA-73666 dUTP + H2O => dUMP + pyrophosphate TAS Homo sapiens 15377 R-HSA-73792 https://reactome.org/PathwayBrowser/#/R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate TAS Homo sapiens 15377 R-HSA-73794 https://reactome.org/PathwayBrowser/#/R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] TAS Homo sapiens 15377 R-HSA-73797 https://reactome.org/PathwayBrowser/#/R-HSA-73797 FAICAR => IMP + H2O TAS Homo sapiens 15377 R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 15377 R-HSA-73815 https://reactome.org/PathwayBrowser/#/R-HSA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate TAS Homo sapiens 15377 R-HSA-74059 https://reactome.org/PathwayBrowser/#/R-HSA-74059 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 15377 R-HSA-74241 https://reactome.org/PathwayBrowser/#/R-HSA-74241 ADA catalyzes the deamination of (deoxy)adenosine TAS Homo sapiens 15377 R-HSA-74247 https://reactome.org/PathwayBrowser/#/R-HSA-74247 XDH oxidizes hypoxanthine to form xanthine TAS Homo sapiens 15377 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 15377 R-HSA-74255 https://reactome.org/PathwayBrowser/#/R-HSA-74255 Guanine + H2O => Xanthine + NH4+ TAS Homo sapiens 15377 R-HSA-74258 https://reactome.org/PathwayBrowser/#/R-HSA-74258 XDH oxidizes xanthine to form urate TAS Homo sapiens 15377 R-HSA-74733 https://reactome.org/PathwayBrowser/#/R-HSA-74733 Insulin receptor de-phosphorylation TAS Homo sapiens 15377 R-HSA-74948 https://reactome.org/PathwayBrowser/#/R-HSA-74948 PP2A dephosphorylates p-RHO to RHO TAS Homo sapiens 15377 R-HSA-75872 https://reactome.org/PathwayBrowser/#/R-HSA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O TAS Homo sapiens 15377 R-HSA-75899 https://reactome.org/PathwayBrowser/#/R-HSA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate TAS Homo sapiens 15377 R-HSA-76031 https://reactome.org/PathwayBrowser/#/R-HSA-76031 2 H2O2 => O2 + 2 H2O TAS Homo sapiens 15377 R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 15377 R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 15377 R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 15377 R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 15377 R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 15377 R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 15377 R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 15377 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 15377 R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 15377 R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 15377 R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 15377 R-HSA-76590 https://reactome.org/PathwayBrowser/#/R-HSA-76590 AMP + H2O => IMP + NH4+ (AMPD) TAS Homo sapiens 15377 R-HSA-77256 https://reactome.org/PathwayBrowser/#/R-HSA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA TAS Homo sapiens 15377 R-HSA-77277 https://reactome.org/PathwayBrowser/#/R-HSA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA TAS Homo sapiens 15377 R-HSA-77301 https://reactome.org/PathwayBrowser/#/R-HSA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA TAS Homo sapiens 15377 R-HSA-77314 https://reactome.org/PathwayBrowser/#/R-HSA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA TAS Homo sapiens 15377 R-HSA-77325 https://reactome.org/PathwayBrowser/#/R-HSA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA TAS Homo sapiens 15377 R-HSA-77333 https://reactome.org/PathwayBrowser/#/R-HSA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA TAS Homo sapiens 15377 R-HSA-77344 https://reactome.org/PathwayBrowser/#/R-HSA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA TAS Homo sapiens 15377 R-HSA-77614 https://reactome.org/PathwayBrowser/#/R-HSA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) TAS Homo sapiens 15377 R-HSA-77615 https://reactome.org/PathwayBrowser/#/R-HSA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) TAS Homo sapiens 15377 R-HSA-83677 https://reactome.org/PathwayBrowser/#/R-HSA-83677 C4 deamination of cytidine TAS Homo sapiens 15377 R-HSA-870437 https://reactome.org/PathwayBrowser/#/R-HSA-870437 USP9X (FAM) deubiquitinates SMAD4 TAS Homo sapiens 15377 R-HSA-877308 https://reactome.org/PathwayBrowser/#/R-HSA-877308 Dephosphorylation of JAKs by PTPs IEA Homo sapiens 15377 R-HSA-8847579 https://reactome.org/PathwayBrowser/#/R-HSA-8847579 SCD5 desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15377 R-HSA-8847912 https://reactome.org/PathwayBrowser/#/R-HSA-8847912 PNPLA7 hydrolyzes LysoPtdCho IEA Homo sapiens 15377 R-HSA-8848053 https://reactome.org/PathwayBrowser/#/R-HSA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol TAS Homo sapiens 15377 R-HSA-8848215 https://reactome.org/PathwayBrowser/#/R-HSA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA TAS Homo sapiens 15377 R-HSA-8848338 https://reactome.org/PathwayBrowser/#/R-HSA-8848338 PNPLA4 hydrolyzes TAG TAS Homo sapiens 15377 R-HSA-8848339 https://reactome.org/PathwayBrowser/#/R-HSA-8848339 PNPLA5 hydrolyzes TAG TAS Homo sapiens 15377 R-HSA-8848355 https://reactome.org/PathwayBrowser/#/R-HSA-8848355 PNPLA4 hydrolyzes retinyl palmitate TAS Homo sapiens 15377 R-HSA-8848484 https://reactome.org/PathwayBrowser/#/R-HSA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane TAS Homo sapiens 15377 R-HSA-8849435 https://reactome.org/PathwayBrowser/#/R-HSA-8849435 PTPN1 dephosphorylates PTK6 TAS Homo sapiens 15377 R-HSA-8849826 https://reactome.org/PathwayBrowser/#/R-HSA-8849826 ST14 hydrolyzes and activates KLK5 IEA Homo sapiens 15377 R-HSA-8849857 https://reactome.org/PathwayBrowser/#/R-HSA-8849857 KLK5 cleaves and activates CELA2 TAS Homo sapiens 15377 R-HSA-8849969 https://reactome.org/PathwayBrowser/#/R-HSA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane TAS Homo sapiens 15377 R-HSA-8850594 https://reactome.org/PathwayBrowser/#/R-HSA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins TAS Homo sapiens 15377 R-HSA-8850831 https://reactome.org/PathwayBrowser/#/R-HSA-8850831 KLK5 cleaves and activates KLK8 TAS Homo sapiens 15377 R-HSA-8850846 https://reactome.org/PathwayBrowser/#/R-HSA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-HSA-8850854 https://reactome.org/PathwayBrowser/#/R-HSA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-HSA-8851110 https://reactome.org/PathwayBrowser/#/R-HSA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-HSA-8851129 https://reactome.org/PathwayBrowser/#/R-HSA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-HSA-8852200 https://reactome.org/PathwayBrowser/#/R-HSA-8852200 Inactivation of LCK by PTPN22 TAS Homo sapiens 15377 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 15377 R-HSA-8853686 https://reactome.org/PathwayBrowser/#/R-HSA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 TAS Homo sapiens 15377 R-HSA-8854173 https://reactome.org/PathwayBrowser/#/R-HSA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 TAS Homo sapiens 15377 R-HSA-8854255 https://reactome.org/PathwayBrowser/#/R-HSA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 15377 R-HSA-8854329 https://reactome.org/PathwayBrowser/#/R-HSA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 15377 R-HSA-8854604 https://reactome.org/PathwayBrowser/#/R-HSA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A TAS Homo sapiens 15377 R-HSA-8854612 https://reactome.org/PathwayBrowser/#/R-HSA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B TAS Homo sapiens 15377 R-HSA-8855381 https://reactome.org/PathwayBrowser/#/R-HSA-8855381 PTPN22 dephosphorylates ZAP70 TAS Homo sapiens 15377 R-HSA-8855490 https://reactome.org/PathwayBrowser/#/R-HSA-8855490 Lactoperoxidase (LPO) produces OSCN- TAS Homo sapiens 15377 R-HSA-8855825 https://reactome.org/PathwayBrowser/#/R-HSA-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) TAS Homo sapiens 15377 R-HSA-8856951 https://reactome.org/PathwayBrowser/#/R-HSA-8856951 PP2A demethylation by PPME1 TAS Homo sapiens 15377 R-HSA-8862184 https://reactome.org/PathwayBrowser/#/R-HSA-8862184 USP48 cleaves polyubiquitin TAS Homo sapiens 15377 R-HSA-8862320 https://reactome.org/PathwayBrowser/#/R-HSA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall TAS Homo sapiens 15377 R-HSA-8863012 https://reactome.org/PathwayBrowser/#/R-HSA-8863012 Calpain cleaves p35 to p25 IEA Homo sapiens 15377 R-HSA-8863804 https://reactome.org/PathwayBrowser/#/R-HSA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 TAS Homo sapiens 15377 R-HSA-8864029 https://reactome.org/PathwayBrowser/#/R-HSA-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) TAS Homo sapiens 15377 R-HSA-8864036 https://reactome.org/PathwayBrowser/#/R-HSA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 TAS Homo sapiens 15377 R-HSA-8864125 https://reactome.org/PathwayBrowser/#/R-HSA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 TAS Homo sapiens 15377 R-HSA-8865667 https://reactome.org/PathwayBrowser/#/R-HSA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids TAS Homo sapiens 15377 R-HSA-8866105 https://reactome.org/PathwayBrowser/#/R-HSA-8866105 CCPs deglutamylate tubulin IEA Homo sapiens 15377 R-HSA-8866405 https://reactome.org/PathwayBrowser/#/R-HSA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 15377 R-HSA-8866542 https://reactome.org/PathwayBrowser/#/R-HSA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol TAS Homo sapiens 15377 R-HSA-8866601 https://reactome.org/PathwayBrowser/#/R-HSA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate TAS Homo sapiens 15377 R-HSA-8866854 https://reactome.org/PathwayBrowser/#/R-HSA-8866854 VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol TAS Homo sapiens 15377 R-HSA-8867047 https://reactome.org/PathwayBrowser/#/R-HSA-8867047 PTPN3 dephosphorylates EPS15 TAS Homo sapiens 15377 R-HSA-8867344 https://reactome.org/PathwayBrowser/#/R-HSA-8867344 OMA1 hydrolyses OPA1 TAS Homo sapiens 15377 R-HSA-8867658 https://reactome.org/PathwayBrowser/#/R-HSA-8867658 PTPN3 dephosphorylates MAPK12 TAS Homo sapiens 15377 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 15377 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 15377 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 15377 R-HSA-8869206 https://reactome.org/PathwayBrowser/#/R-HSA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate TAS Homo sapiens 15377 R-HSA-8869425 https://reactome.org/PathwayBrowser/#/R-HSA-8869425 PLA1A hydrolyses PS to 2-acyl LPS TAS Homo sapiens 15377 R-HSA-8869456 https://reactome.org/PathwayBrowser/#/R-HSA-8869456 USP4 deubiquitinate TRAF2,TRAF6 TAS Homo sapiens 15377 R-HSA-8869506 https://reactome.org/PathwayBrowser/#/R-HSA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 TAS Homo sapiens 15377 R-HSA-8870346 https://reactome.org/PathwayBrowser/#/R-HSA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose TAS Homo sapiens 15377 R-HSA-8874435 https://reactome.org/PathwayBrowser/#/R-HSA-8874435 THEM86B hydrolyses PMCHO, PMETAM TAS Homo sapiens 15377 R-HSA-8875443 https://reactome.org/PathwayBrowser/#/R-HSA-8875443 USP8 deubiquitinates LRIG1 TAS Homo sapiens 15377 R-HSA-8878581 https://reactome.org/PathwayBrowser/#/R-HSA-8878581 TYRP1 oxidises DHICA to IQCA TAS Homo sapiens 15377 R-HSA-8878654 https://reactome.org/PathwayBrowser/#/R-HSA-8878654 ACP6 hydrolyses MYS-LPA TAS Homo sapiens 15377 R-HSA-8878787 https://reactome.org/PathwayBrowser/#/R-HSA-8878787 ALPI dimer hydrolyses phosphate monoesters TAS Homo sapiens 15377 R-HSA-888548 https://reactome.org/PathwayBrowser/#/R-HSA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA TAS Homo sapiens 15377 R-HSA-8932633 https://reactome.org/PathwayBrowser/#/R-HSA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE TAS Homo sapiens 15377 R-HSA-8933328 https://reactome.org/PathwayBrowser/#/R-HSA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 TAS Homo sapiens 15377 R-HSA-8933635 https://reactome.org/PathwayBrowser/#/R-HSA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide TAS Homo sapiens 15377 R-HSA-893597 https://reactome.org/PathwayBrowser/#/R-HSA-893597 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [mitochondrial] TAS Homo sapiens 15377 R-HSA-893609 https://reactome.org/PathwayBrowser/#/R-HSA-893609 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [cytosolic] TAS Homo sapiens 15377 R-HSA-8936442 https://reactome.org/PathwayBrowser/#/R-HSA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds TAS Homo sapiens 15377 R-HSA-8937442 https://reactome.org/PathwayBrowser/#/R-HSA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) TAS Homo sapiens 15377 R-HSA-8937767 https://reactome.org/PathwayBrowser/#/R-HSA-8937767 PTPN11 dephosphorylates RUNX1 TAS Homo sapiens 15377 R-HSA-8938076 https://reactome.org/PathwayBrowser/#/R-HSA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose TAS Homo sapiens 15377 R-HSA-8938314 https://reactome.org/PathwayBrowser/#/R-HSA-8938314 ENPPs hydrolyse CoA-SH to PPANT, PAP TAS Homo sapiens 15377 R-HSA-8940070 https://reactome.org/PathwayBrowser/#/R-HSA-8940070 NT5E:Zn2+ hydrolyses NAD+ TAS Homo sapiens 15377 R-HSA-8940074 https://reactome.org/PathwayBrowser/#/R-HSA-8940074 NT5E:Zn2+ hydrolyses NMN TAS Homo sapiens 15377 R-HSA-8940388 https://reactome.org/PathwayBrowser/#/R-HSA-8940388 GPLD1 hydrolyses GPI-anchors from proteins TAS Homo sapiens 15377 R-HSA-8941411 https://reactome.org/PathwayBrowser/#/R-HSA-8941411 OSCN- reacts with Cys residues TAS Homo sapiens 15377 R-HSA-8943279 https://reactome.org/PathwayBrowser/#/R-HSA-8943279 GGT dimers hydrolyse GSH TAS Homo sapiens 15377 R-HSA-8952069 https://reactome.org/PathwayBrowser/#/R-HSA-8952069 HDAC4 deacetylates RUNX3 TAS Homo sapiens 15377 R-HSA-8952137 https://reactome.org/PathwayBrowser/#/R-HSA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate TAS Homo sapiens 15377 R-HSA-8952251 https://reactome.org/PathwayBrowser/#/R-HSA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) TAS Homo sapiens 15377 R-HSA-8952903 https://reactome.org/PathwayBrowser/#/R-HSA-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) TAS Homo sapiens 15377 R-HSA-8953339 https://reactome.org/PathwayBrowser/#/R-HSA-8953339 DNPH1 hydrolyses dGMP TAS Homo sapiens 15377 R-HSA-8953499 https://reactome.org/PathwayBrowser/#/R-HSA-8953499 IMPAD1 hydrolyses PAP to AMP TAS Homo sapiens 15377 R-HSA-8954398 https://reactome.org/PathwayBrowser/#/R-HSA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG TAS Homo sapiens 15377 R-HSA-8955712 https://reactome.org/PathwayBrowser/#/R-HSA-8955712 SVBP:VASH1,VASH2 hydrolyzes the terminal L-Tyr residue from alphaY-beta tubulin dimer IEA Homo sapiens 15377 R-HSA-8955794 https://reactome.org/PathwayBrowser/#/R-HSA-8955794 PGP:Mg2+ dimer hydrolyses 3PG to glycerol IEA Homo sapiens 15377 R-HSA-8955817 https://reactome.org/PathwayBrowser/#/R-HSA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH TAS Homo sapiens 15377 R-HSA-8957389 https://reactome.org/PathwayBrowser/#/R-HSA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA TAS Homo sapiens 15377 R-HSA-8959510 https://reactome.org/PathwayBrowser/#/R-HSA-8959510 SEPHS2 phosphorylates H2Se to form SELP TAS Homo sapiens 15377 R-HSA-8979996 https://reactome.org/PathwayBrowser/#/R-HSA-8979996 LIPs hydrolyze TG to DAG and LCFA TAS Homo sapiens 15377 R-HSA-8980228 https://reactome.org/PathwayBrowser/#/R-HSA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA TAS Homo sapiens 15377 R-HSA-8981637 https://reactome.org/PathwayBrowser/#/R-HSA-8981637 RHOA GAPs stimulate RHOA GTPase activity TAS Homo sapiens 15377 R-HSA-8985594 https://reactome.org/PathwayBrowser/#/R-HSA-8985594 MYO9B inactivates RHOA TAS Homo sapiens 15377 R-HSA-8986083 https://reactome.org/PathwayBrowser/#/R-HSA-8986083 USP33 deubiquitinates ROBO1 TAS Homo sapiens 15377 R-HSA-9008822 https://reactome.org/PathwayBrowser/#/R-HSA-9008822 PPM1D dephosphorylates RUNX2 TAS Homo sapiens 15377 R-HSA-9009950 https://reactome.org/PathwayBrowser/#/R-HSA-9009950 PDE12 cleaves 2'-5' oligoadenylates TAS Homo sapiens 15377 R-HSA-901024 https://reactome.org/PathwayBrowser/#/R-HSA-901024 MAN1B1 hydrolyses 1,2-linked mannose (a branch) TAS Homo sapiens 15377 R-HSA-901036 https://reactome.org/PathwayBrowser/#/R-HSA-901036 MAN1B1 hydrolyses a second 1,2-linked mannose (a branch) TAS Homo sapiens 15377 R-HSA-901039 https://reactome.org/PathwayBrowser/#/R-HSA-901039 MAN1B1 hydrolyses 1,2-linked mannose (c branch) TAS Homo sapiens 15377 R-HSA-901074 https://reactome.org/PathwayBrowser/#/R-HSA-901074 MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch) TAS Homo sapiens 15377 R-HSA-9013022 https://reactome.org/PathwayBrowser/#/R-HSA-9013022 RHOB GAPs stimulate RHOB GTPase activity TAS Homo sapiens 15377 R-HSA-9013111 https://reactome.org/PathwayBrowser/#/R-HSA-9013111 RHOC GAPs stimulate RHOC GTPase activity TAS Homo sapiens 15377 R-HSA-9013144 https://reactome.org/PathwayBrowser/#/R-HSA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity TAS Homo sapiens 15377 R-HSA-9013161 https://reactome.org/PathwayBrowser/#/R-HSA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity TAS Homo sapiens 15377 R-HSA-9013437 https://reactome.org/PathwayBrowser/#/R-HSA-9013437 RHOD GAPs stimulate RHOD GTPase activity TAS Homo sapiens 15377 R-HSA-9014295 https://reactome.org/PathwayBrowser/#/R-HSA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity TAS Homo sapiens 15377 R-HSA-9014434 https://reactome.org/PathwayBrowser/#/R-HSA-9014434 RHOG GAPs stimulate RHOG GTPase activity TAS Homo sapiens 15377 R-HSA-9014627 https://reactome.org/PathwayBrowser/#/R-HSA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA TAS Homo sapiens 15377 R-HSA-9014741 https://reactome.org/PathwayBrowser/#/R-HSA-9014741 PXLP-K56-SRR dimer deaminates D-Ser TAS Homo sapiens 15377 R-HSA-9017488 https://reactome.org/PathwayBrowser/#/R-HSA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity TAS Homo sapiens 15377 R-HSA-9018745 https://reactome.org/PathwayBrowser/#/R-HSA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity TAS Homo sapiens 15377 R-HSA-9018806 https://reactome.org/PathwayBrowser/#/R-HSA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity TAS Homo sapiens 15377 R-HSA-9018814 https://reactome.org/PathwayBrowser/#/R-HSA-9018814 RHOT1 hydrolyzes GTP TAS Homo sapiens 15377 R-HSA-9018826 https://reactome.org/PathwayBrowser/#/R-HSA-9018826 RHOT2 hydrolyzes GTP TAS Homo sapiens 15377 R-HSA-9018862 https://reactome.org/PathwayBrowser/#/R-HSA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 TAS Homo sapiens 15377 R-HSA-9018868 https://reactome.org/PathwayBrowser/#/R-HSA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE TAS Homo sapiens 15377 R-HSA-9018877 https://reactome.org/PathwayBrowser/#/R-HSA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 TAS Homo sapiens 15377 R-HSA-9018895 https://reactome.org/PathwayBrowser/#/R-HSA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE TAS Homo sapiens 15377 R-HSA-9020252 https://reactome.org/PathwayBrowser/#/R-HSA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 TAS Homo sapiens 15377 R-HSA-9020253 https://reactome.org/PathwayBrowser/#/R-HSA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 TAS Homo sapiens 15377 R-HSA-9020257 https://reactome.org/PathwayBrowser/#/R-HSA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 TAS Homo sapiens 15377 R-HSA-9020258 https://reactome.org/PathwayBrowser/#/R-HSA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 TAS Homo sapiens 15377 R-HSA-9020270 https://reactome.org/PathwayBrowser/#/R-HSA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 TAS Homo sapiens 15377 R-HSA-9020271 https://reactome.org/PathwayBrowser/#/R-HSA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA TAS Homo sapiens 15377 R-HSA-9020273 https://reactome.org/PathwayBrowser/#/R-HSA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA TAS Homo sapiens 15377 R-HSA-9023159 https://reactome.org/PathwayBrowser/#/R-HSA-9023159 Carboxypeptidase E hydrolyzes Insulin(57-89) to yield C-peptide (Insulin(57-87)) IEA Homo sapiens 15377 R-HSA-9023163 https://reactome.org/PathwayBrowser/#/R-HSA-9023163 Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54) IEA Homo sapiens 15377 R-HSA-9023178 https://reactome.org/PathwayBrowser/#/R-HSA-9023178 PCSK2 cleaves Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) IEA Homo sapiens 15377 R-HSA-9023196 https://reactome.org/PathwayBrowser/#/R-HSA-9023196 PCSK1 cleaves proinsulin to yield Insulin(25-56) and Insulin(57-110) IEA Homo sapiens 15377 R-HSA-9024890 https://reactome.org/PathwayBrowser/#/R-HSA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 TAS Homo sapiens 15377 R-HSA-9024973 https://reactome.org/PathwayBrowser/#/R-HSA-9024973 Epoxide hydrolase hydrolyses 13(S),14(S)-epoxy-DHA to MaR1 TAS Homo sapiens 15377 R-HSA-9025998 https://reactome.org/PathwayBrowser/#/R-HSA-9025998 Epoxide hydrolase hydrolyses 13,14-epoxy-DPAn-3 to MaR1n-3 DPA or MaR2n-3 DPA TAS Homo sapiens 15377 R-HSA-9026000 https://reactome.org/PathwayBrowser/#/R-HSA-9026000 Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA TAS Homo sapiens 15377 R-HSA-9026008 https://reactome.org/PathwayBrowser/#/R-HSA-9026008 Epoxide hydrolase hydrolyses 7,8-epoxy-HDPAn-3 to RvD1n-3DPA or RvD2n-3DPA TAS Homo sapiens 15377 R-HSA-9026544 https://reactome.org/PathwayBrowser/#/R-HSA-9026544 Non-enzymatic hydrolysis hydrolyses 13(S),14(S)-epoxy-DHA to 7-epi-MaR1 TAS Homo sapiens 15377 R-HSA-9026757 https://reactome.org/PathwayBrowser/#/R-HSA-9026757 GGT hydrolyses MCTR1 to MCTR2 TAS Homo sapiens 15377 R-HSA-9026771 https://reactome.org/PathwayBrowser/#/R-HSA-9026771 DPEP hydrolyses MCTR2 to MCTR3 TAS Homo sapiens 15377 R-HSA-9026907 https://reactome.org/PathwayBrowser/#/R-HSA-9026907 GGT hydrolyses PCTR2 to PCTR3 TAS Homo sapiens 15377 R-HSA-9026912 https://reactome.org/PathwayBrowser/#/R-HSA-9026912 GGT hydrolyses PCTR1 to PCTR2 TAS Homo sapiens 15377 R-HSA-9026916 https://reactome.org/PathwayBrowser/#/R-HSA-9026916 GGT hydrolyses RCTR2 to RCTR3 TAS Homo sapiens 15377 R-HSA-9026927 https://reactome.org/PathwayBrowser/#/R-HSA-9026927 GGT hydrolyses RCTR1 to RCTR2 TAS Homo sapiens 15377 R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 15377 R-HSA-9027043 https://reactome.org/PathwayBrowser/#/R-HSA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA TAS Homo sapiens 15377 R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 15377 R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 15377 R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 15377 R-HSA-9027670 https://reactome.org/PathwayBrowser/#/R-HSA-9027670 ESTG binding induces ESR depalmitoylation TAS Homo sapiens 15377 R-HSA-9028260 https://reactome.org/PathwayBrowser/#/R-HSA-9028260 δ12-PGJ3 spontaneously dehydrates to 15d-PGJ3 TAS Homo sapiens 15377 R-HSA-9028273 https://reactome.org/PathwayBrowser/#/R-HSA-9028273 PGH3 spontaneously dehydrates to PGJ3 TAS Homo sapiens 15377 R-HSA-9032478 https://reactome.org/PathwayBrowser/#/R-HSA-9032478 EPOR-associated PLCG hydrolyzes 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate IEA Homo sapiens 15377 R-HSA-9033478 https://reactome.org/PathwayBrowser/#/R-HSA-9033478 USP9X hydrolyzes Ub:PEX5S yielding PEX5S and Ubiquitin IEA Homo sapiens 15377 R-HSA-9033490 https://reactome.org/PathwayBrowser/#/R-HSA-9033490 TYSND1 cleaves PHYH IEA Homo sapiens 15377 R-HSA-9033491 https://reactome.org/PathwayBrowser/#/R-HSA-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin TAS Homo sapiens 15377 R-HSA-9033506 https://reactome.org/PathwayBrowser/#/R-HSA-9033506 TYSND1 cleaves AGPS IEA Homo sapiens 15377 R-HSA-9033515 https://reactome.org/PathwayBrowser/#/R-HSA-9033515 TYSND1 cleaves ACOX1 IEA Homo sapiens 15377 R-HSA-9033520 https://reactome.org/PathwayBrowser/#/R-HSA-9033520 TYSND1 cleaves TYSND1 TAS Homo sapiens 15377 R-HSA-9033524 https://reactome.org/PathwayBrowser/#/R-HSA-9033524 TYSND1 cleaves SCP2 IEA Homo sapiens 15377 R-HSA-9033529 https://reactome.org/PathwayBrowser/#/R-HSA-9033529 TYSND1 cleaves ACAA1 IEA Homo sapiens 15377 R-HSA-9033530 https://reactome.org/PathwayBrowser/#/R-HSA-9033530 TYSND1 cleaves HSD17B4 IEA Homo sapiens 15377 R-HSA-9034539 https://reactome.org/PathwayBrowser/#/R-HSA-9034539 PXLP-K56-SRR dimer deaminates L-Ser TAS Homo sapiens 15377 R-HSA-9035966 https://reactome.org/PathwayBrowser/#/R-HSA-9035966 Defective GGT1 does not hydrolyse GSH TAS Homo sapiens 15377 R-HSA-9035976 https://reactome.org/PathwayBrowser/#/R-HSA-9035976 Defective HEXA does not cleave the terminall GalNAc from small HA fragments TAS Homo sapiens 15377 R-HSA-9035978 https://reactome.org/PathwayBrowser/#/R-HSA-9035978 Defective HEXA does not cleave the terminal GalNAc from keratan sulfate TAS Homo sapiens 15377 R-HSA-9035982 https://reactome.org/PathwayBrowser/#/R-HSA-9035982 Defective HEXB does not cleave the terminal GalNAc from HA fragments TAS Homo sapiens 15377 R-HSA-9035983 https://reactome.org/PathwayBrowser/#/R-HSA-9035983 Defective HEXB does not cleave the terminal GalNAc from keratan sulfate TAS Homo sapiens 15377 R-HSA-9036008 https://reactome.org/PathwayBrowser/#/R-HSA-9036008 Defective MAN1B1 does not hydrolyse a second 1,2-linked mannose (a branch) TAS Homo sapiens 15377 R-HSA-9036011 https://reactome.org/PathwayBrowser/#/R-HSA-9036011 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (b branch) TAS Homo sapiens 15377 R-HSA-9036012 https://reactome.org/PathwayBrowser/#/R-HSA-9036012 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (c branch) TAS Homo sapiens 15377 R-HSA-9036037 https://reactome.org/PathwayBrowser/#/R-HSA-9036037 Defective IDUA does not hydrolyse Heparan sulfate chain(1) TAS Homo sapiens 15377 R-HSA-9036041 https://reactome.org/PathwayBrowser/#/R-HSA-9036041 Defective IDUA does not hydrolyse the unsulfated alpha-L-iduronosidic link in DS TAS Homo sapiens 15377 R-HSA-9036046 https://reactome.org/PathwayBrowser/#/R-HSA-9036046 Defective IDS does not hydrolyse Heparan sulfate chain(5) TAS Homo sapiens 15377 R-HSA-9036050 https://reactome.org/PathwayBrowser/#/R-HSA-9036050 Defective SGSH does not hydrolyse Heparan sulfate chain(2) TAS Homo sapiens 15377 R-HSA-9036052 https://reactome.org/PathwayBrowser/#/R-HSA-9036052 Defective NAGLU does not hydrolyse heparan chain(2) TAS Homo sapiens 15377 R-HSA-9036061 https://reactome.org/PathwayBrowser/#/R-HSA-9036061 Defective GLB1 does not hydrolyse linker chain(2) TAS Homo sapiens 15377 R-HSA-9036065 https://reactome.org/PathwayBrowser/#/R-HSA-9036065 Defective ARSB does not hydrolyse DS TAS Homo sapiens 15377 R-HSA-9036068 https://reactome.org/PathwayBrowser/#/R-HSA-9036068 Defective GUSB does not hydrolyse GlcA-β1,3-GlcNAc TAS Homo sapiens 15377 R-HSA-9036070 https://reactome.org/PathwayBrowser/#/R-HSA-9036070 Defective GUSB does not hydrolyse CS/HS precursor TAS Homo sapiens 15377 R-HSA-9036077 https://reactome.org/PathwayBrowser/#/R-HSA-9036077 Defective HYAL1 does not hydrolyse (HA)50 TAS Homo sapiens 15377 R-HSA-9036727 https://reactome.org/PathwayBrowser/#/R-HSA-9036727 GAA hydrolyzes lysosomal glycogen TAS Homo sapiens 15377 R-HSA-9036729 https://reactome.org/PathwayBrowser/#/R-HSA-9036729 Defective GAA does not hydrolyze lysosomal glycogen TAS Homo sapiens 15377 R-HSA-9037761 https://reactome.org/PathwayBrowser/#/R-HSA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 TAS Homo sapiens 15377 R-HSA-917841 https://reactome.org/PathwayBrowser/#/R-HSA-917841 Acidification of Tf:TfR1 containing endosome TAS Homo sapiens 15377 R-HSA-917891 https://reactome.org/PathwayBrowser/#/R-HSA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ TAS Homo sapiens 15377 R-HSA-917933 https://reactome.org/PathwayBrowser/#/R-HSA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ TAS Homo sapiens 15377 R-HSA-917979 https://reactome.org/PathwayBrowser/#/R-HSA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-936381 https://reactome.org/PathwayBrowser/#/R-HSA-936381 OTUD5 deubiquitinates TRAF3 TAS Homo sapiens 15377 R-HSA-936802 https://reactome.org/PathwayBrowser/#/R-HSA-936802 ATP7A transports cytosolic Cu2+ to extracellular region TAS Homo sapiens 15377 R-HSA-936883 https://reactome.org/PathwayBrowser/#/R-HSA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen TAS Homo sapiens 15377 R-HSA-936895 https://reactome.org/PathwayBrowser/#/R-HSA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen TAS Homo sapiens 15377 R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 15377 R-HSA-937311 https://reactome.org/PathwayBrowser/#/R-HSA-937311 ATP12A:ATP4B exchanges K+ for H+ TAS Homo sapiens 15377 R-HSA-939763 https://reactome.org/PathwayBrowser/#/R-HSA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane TAS Homo sapiens 15377 R-HSA-947531 https://reactome.org/PathwayBrowser/#/R-HSA-947531 Molybdenum ion transfer onto molybdopterin TAS Homo sapiens 15377 R-HSA-947535 https://reactome.org/PathwayBrowser/#/R-HSA-947535 Cyclisation of GTP to precursor Z TAS Homo sapiens 15377 R-HSA-947541 https://reactome.org/PathwayBrowser/#/R-HSA-947541 Sulfhydrylation and ring cleavage of precursor Z TAS Homo sapiens 15377 R-HSA-947591 https://reactome.org/PathwayBrowser/#/R-HSA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane TAS Homo sapiens 15377 R-HSA-9603719 https://reactome.org/PathwayBrowser/#/R-HSA-9603719 Protein tyrosine phosphatases dephosphorylate NTRK3 IEA Homo sapiens 15377 R-HSA-9615042 https://reactome.org/PathwayBrowser/#/R-HSA-9615042 Viral 2',5'-PDE cleaves 2'-5' oligoadenylates TAS Homo sapiens 15377 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 15377 R-HSA-9619430 https://reactome.org/PathwayBrowser/#/R-HSA-9619430 PPM1E dephosphorylates CAMK4 IEA Homo sapiens 15377 R-HSA-9619449 https://reactome.org/PathwayBrowser/#/R-HSA-9619449 PPM1F dephosphorylates p-T286-CaMKII IEA Homo sapiens 15377 R-HSA-9619467 https://reactome.org/PathwayBrowser/#/R-HSA-9619467 PPM1F dephosphorylates CAMK1 IEA Homo sapiens 15377 R-HSA-9620103 https://reactome.org/PathwayBrowser/#/R-HSA-9620103 ALDH2 transforms GTN to NO TAS Homo sapiens 15377 R-HSA-9624893 https://reactome.org/PathwayBrowser/#/R-HSA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes TAS Homo sapiens 15377 R-HSA-9625540 https://reactome.org/PathwayBrowser/#/R-HSA-9625540 Cys-sulfenyl chloride is converted to Cys-sulfenic acid TAS Homo sapiens 15377 R-HSA-9625548 https://reactome.org/PathwayBrowser/#/R-HSA-9625548 Hypochlorous acid (HOCL) oxidizes Cys residues to form Cys-sulfenyl chloride TAS Homo sapiens 15377 R-HSA-9625904 https://reactome.org/PathwayBrowser/#/R-HSA-9625904 Hypochlorous acid (HOCL) reacts with Lys residue to form Lys-monochloramine TAS Homo sapiens 15377 R-HSA-9625913 https://reactome.org/PathwayBrowser/#/R-HSA-9625913 Hypochlorous acid (HOCL) reacts with Lys-monochloramine TAS Homo sapiens 15377 R-HSA-9626753 https://reactome.org/PathwayBrowser/#/R-HSA-9626753 H2O2 oxidizes Cys residues to form Cys-sulfenic acid TAS Homo sapiens 15377 R-HSA-9629675 https://reactome.org/PathwayBrowser/#/R-HSA-9629675 PDE3A hydrolyses cAMP to AMP TAS Homo sapiens 15377 R-HSA-9635461 https://reactome.org/PathwayBrowser/#/R-HSA-9635461 PtpA dephosphorylates GSK3A TAS Homo sapiens 15377 R-HSA-9635739 https://reactome.org/PathwayBrowser/#/R-HSA-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs TAS Homo sapiens 15377 R-HSA-9636439 https://reactome.org/PathwayBrowser/#/R-HSA-9636439 PtpA:Ub dephosphorylates p-Y133-VPS33B TAS Homo sapiens 15377 R-HSA-9636457 https://reactome.org/PathwayBrowser/#/R-HSA-9636457 SapM dephosphorylates PI3P TAS Homo sapiens 15377 R-HSA-9636684 https://reactome.org/PathwayBrowser/#/R-HSA-9636684 ndkA dephosphorylates RAB5A:GTP,RAB7A:GTP TAS Homo sapiens 15377 R-HSA-9637699 https://reactome.org/PathwayBrowser/#/R-HSA-9637699 CpnT hydrolyses NAD+ TAS Homo sapiens 15377 R-HSA-9638046 https://reactome.org/PathwayBrowser/#/R-HSA-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 15377 R-HSA-9638075 https://reactome.org/PathwayBrowser/#/R-HSA-9638075 HEXB cleaves the terminal GalNAc from DS TAS Homo sapiens 15377 R-HSA-9638076 https://reactome.org/PathwayBrowser/#/R-HSA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments TAS Homo sapiens 15377 R-HSA-9638078 https://reactome.org/PathwayBrowser/#/R-HSA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate TAS Homo sapiens 15377 R-HSA-9638120 https://reactome.org/PathwayBrowser/#/R-HSA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 15377 R-HSA-9640307 https://reactome.org/PathwayBrowser/#/R-HSA-9640307 DeHA hydrolyses to 2,3-DKG TAS Homo sapiens 15377 R-HSA-9640316 https://reactome.org/PathwayBrowser/#/R-HSA-9640316 DeHA hydrolyses to threonate and oxalate TAS Homo sapiens 15377 R-HSA-9640321 https://reactome.org/PathwayBrowser/#/R-HSA-9640321 2,3-DKG hydrolyses to ERU and oxalate TAS Homo sapiens 15377 R-HSA-9644869 https://reactome.org/PathwayBrowser/#/R-HSA-9644869 p-S54-PDE4B hydrolyses cAMP TAS Homo sapiens 15377 R-HSA-9647994 https://reactome.org/PathwayBrowser/#/R-HSA-9647994 RAS proteins are depalmitoylated TAS Homo sapiens 15377 R-HSA-965067 https://reactome.org/PathwayBrowser/#/R-HSA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP TAS Homo sapiens 15377 R-HSA-965079 https://reactome.org/PathwayBrowser/#/R-HSA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP TAS Homo sapiens 15377 R-HSA-9652816 https://reactome.org/PathwayBrowser/#/R-HSA-9652816 Constitutively active MAPK1 mutants are not dephosphorylated by DUSPs TAS Homo sapiens 15377 R-HSA-9653514 https://reactome.org/PathwayBrowser/#/R-HSA-9653514 USP17L2 deubiquitinates RCE1 TAS Homo sapiens 15377 R-HSA-9656891 https://reactome.org/PathwayBrowser/#/R-HSA-9656891 OPN1SW binds 11cRAL TAS Homo sapiens 15377 R-HSA-9656893 https://reactome.org/PathwayBrowser/#/R-HSA-9656893 OPN1MW binds 11cRAL TAS Homo sapiens 15377 R-HSA-9658445 https://reactome.org/PathwayBrowser/#/R-HSA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs TAS Homo sapiens 15377 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 15377 R-HSA-9660536 https://reactome.org/PathwayBrowser/#/R-HSA-9660536 SHOC2 M173I disrupts the SHOC2:MRAS:PP1 complex TAS Homo sapiens 15377 R-HSA-9660538 https://reactome.org/PathwayBrowser/#/R-HSA-9660538 Mutant MRAS:SHOC2:PPP1CC complexes dephosphorylate inactive RAFs TAS Homo sapiens 15377 R-HSA-9661417 https://reactome.org/PathwayBrowser/#/R-HSA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-9661820 https://reactome.org/PathwayBrowser/#/R-HSA-9661820 Bacterial GUSB hydrolyses BDG to BIL TAS Homo sapiens 15377 R-HSA-9667952 https://reactome.org/PathwayBrowser/#/R-HSA-9667952 ANKLE2 is deacetylated by SIRT2 TAS Homo sapiens 15377 R-HSA-9668415 https://reactome.org/PathwayBrowser/#/R-HSA-9668415 VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope TAS Homo sapiens 15377 R-HSA-9668419 https://reactome.org/PathwayBrowser/#/R-HSA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites TAS Homo sapiens 15377 R-HSA-9673053 https://reactome.org/PathwayBrowser/#/R-HSA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe TAS Homo sapiens 15377 R-HSA-9673054 https://reactome.org/PathwayBrowser/#/R-HSA-9673054 PM20D1 hydrolyzes oleoyl-phe TAS Homo sapiens 15377 R-HSA-9674127 https://reactome.org/PathwayBrowser/#/R-HSA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 TAS Homo sapiens 15377 R-HSA-9680388 https://reactome.org/PathwayBrowser/#/R-HSA-9680388 CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine IEA Homo sapiens 15377 R-HSA-9682603 https://reactome.org/PathwayBrowser/#/R-HSA-9682603 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 15377 R-HSA-9683663 https://reactome.org/PathwayBrowser/#/R-HSA-9683663 N-glycan trimming of Spike TAS Homo sapiens 15377 R-HSA-9684016 https://reactome.org/PathwayBrowser/#/R-HSA-9684016 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 15377 R-HSA-9684017 https://reactome.org/PathwayBrowser/#/R-HSA-9684017 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 15377 R-HSA-9684018 https://reactome.org/PathwayBrowser/#/R-HSA-9684018 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 15377 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 15377 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 15377 R-HSA-9684321 https://reactome.org/PathwayBrowser/#/R-HSA-9684321 nsp3 cleaves nsp1-4 TAS Homo sapiens 15377 R-HSA-9684336 https://reactome.org/PathwayBrowser/#/R-HSA-9684336 nsp1-4 cleaves itself TAS Homo sapiens 15377 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 15377 R-HSA-9684351 https://reactome.org/PathwayBrowser/#/R-HSA-9684351 pp1a cleaves itself TAS Homo sapiens 15377 R-HSA-9684352 https://reactome.org/PathwayBrowser/#/R-HSA-9684352 nsp3-4 cleaves itself TAS Homo sapiens 15377 R-HSA-9686524 https://reactome.org/PathwayBrowser/#/R-HSA-9686524 PP6-PPP6R3 dephosphorylates TERF2 TAS Homo sapiens 15377 R-HSA-9693282 https://reactome.org/PathwayBrowser/#/R-HSA-9693282 RHOF GAPs stimulate RHOF GTPase activity TAS Homo sapiens 15377 R-HSA-9694338 https://reactome.org/PathwayBrowser/#/R-HSA-9694338 nsp1-4 cleaves itself IEA Homo sapiens 15377 R-HSA-9694364 https://reactome.org/PathwayBrowser/#/R-HSA-9694364 N-glycan glucose trimming of Spike TAS Homo sapiens 15377 R-HSA-9694377 https://reactome.org/PathwayBrowser/#/R-HSA-9694377 pp1a cleaves itself TAS Homo sapiens 15377 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 15377 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 15377 R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 15377 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 15377 R-HSA-9694601 https://reactome.org/PathwayBrowser/#/R-HSA-9694601 nsp3-4 cleaves itself IEA Homo sapiens 15377 R-HSA-9694625 https://reactome.org/PathwayBrowser/#/R-HSA-9694625 nsp3 cleaves nsp1-4 TAS Homo sapiens 15377 R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 15377 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 15377 R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 15377 R-HSA-9698408 https://reactome.org/PathwayBrowser/#/R-HSA-9698408 PTPRJ dephosphorylates active FLT3 TAS Homo sapiens 15377 R-HSA-9700200 https://reactome.org/PathwayBrowser/#/R-HSA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers TAS Homo sapiens 15377 R-HSA-9701507 https://reactome.org/PathwayBrowser/#/R-HSA-9701507 PTPN6 dephosphorylates JAK3 TAS Homo sapiens 15377 R-HSA-9701565 https://reactome.org/PathwayBrowser/#/R-HSA-9701565 HDACs deacetylate p-STAT3 dimers TAS Homo sapiens 15377 R-HSA-9705507 https://reactome.org/PathwayBrowser/#/R-HSA-9705507 PDE3B hydrolyses cAMP to AMP TAS Homo sapiens 15377 R-HSA-9706399 https://reactome.org/PathwayBrowser/#/R-HSA-9706399 RHOBTB3 hydrolyzes ATP TAS Homo sapiens 15377 R-HSA-9708261 https://reactome.org/PathwayBrowser/#/R-HSA-9708261 PDE4A hydrolyses cAMP to AMP TAS Homo sapiens 15377 R-HSA-9709360 https://reactome.org/PathwayBrowser/#/R-HSA-9709360 H2O2 reduces MetHb TAS Homo sapiens 15377 R-HSA-9717205 https://reactome.org/PathwayBrowser/#/R-HSA-9717205 GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG IEA Homo sapiens 15377 R-HSA-9727198 https://reactome.org/PathwayBrowser/#/R-HSA-9727198 ATP4A:ATP4B exchanges K+ for H+ TAS Homo sapiens 15377 R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 15377 R-HSA-9727349 https://reactome.org/PathwayBrowser/#/R-HSA-9727349 XDH dehydrogenates xanthine to form urate TAS Homo sapiens 15377 R-HSA-9727567 https://reactome.org/PathwayBrowser/#/R-HSA-9727567 CES1 hydrolyses sacubitril to sacubitrilat TAS Homo sapiens 15377 R-HSA-9729704 https://reactome.org/PathwayBrowser/#/R-HSA-9729704 SARS-CoV-2 3CLpro dimer cleaves TAB1 TAS Homo sapiens 15377 R-HSA-9729725 https://reactome.org/PathwayBrowser/#/R-HSA-9729725 SARS-CoV-2 nsp3 deISGylates ISGylated IRF3 TAS Homo sapiens 15377 R-HSA-9729730 https://reactome.org/PathwayBrowser/#/R-HSA-9729730 SARS-CoV-2 nsp3 cleaves IRF3 TAS Homo sapiens 15377 R-HSA-9729741 https://reactome.org/PathwayBrowser/#/R-HSA-9729741 SARS-CoV-2 3CLpro dimer cleaves NLRP12 TAS Homo sapiens 15377 R-HSA-9731228 https://reactome.org/PathwayBrowser/#/R-HSA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP TAS Homo sapiens 15377 R-HSA-9731590 https://reactome.org/PathwayBrowser/#/R-HSA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP TAS Homo sapiens 15377 R-HSA-9731613 https://reactome.org/PathwayBrowser/#/R-HSA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP TAS Homo sapiens 15377 R-HSA-9731632 https://reactome.org/PathwayBrowser/#/R-HSA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP TAS Homo sapiens 15377 R-HSA-9731661 https://reactome.org/PathwayBrowser/#/R-HSA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine TAS Homo sapiens 15377 R-HSA-9734745 https://reactome.org/PathwayBrowser/#/R-HSA-9734745 Defective ADA does not deaminate (deoxy)adenosine TAS Homo sapiens 15377 R-HSA-9748945 https://reactome.org/PathwayBrowser/#/R-HSA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP TAS Homo sapiens 15377 R-HSA-9748957 https://reactome.org/PathwayBrowser/#/R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP TAS Homo sapiens 15377 R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 15377 R-HSA-9749609 https://reactome.org/PathwayBrowser/#/R-HSA-9749609 BCHE hydrolyzes ASA- TAS Homo sapiens 15377 R-HSA-9749647 https://reactome.org/PathwayBrowser/#/R-HSA-9749647 CES2 hydrolyzes ASA- TAS Homo sapiens 15377 R-HSA-9749792 https://reactome.org/PathwayBrowser/#/R-HSA-9749792 CES1,CES2 hydrolyze ASA- to ST TAS Homo sapiens 15377 R-HSA-9749986 https://reactome.org/PathwayBrowser/#/R-HSA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA TAS Homo sapiens 15377 R-HSA-9750016 https://reactome.org/PathwayBrowser/#/R-HSA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA TAS Homo sapiens 15377 R-HSA-9750546 https://reactome.org/PathwayBrowser/#/R-HSA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-9750555 https://reactome.org/PathwayBrowser/#/R-HSA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP TAS Homo sapiens 15377 R-HSA-9750617 https://reactome.org/PathwayBrowser/#/R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-9750656 https://reactome.org/PathwayBrowser/#/R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells TAS Homo sapiens 15377 R-HSA-9750942 https://reactome.org/PathwayBrowser/#/R-HSA-9750942 USP14 deubiquitinates NLRC5 TAS Homo sapiens 15377 R-HSA-9753278 https://reactome.org/PathwayBrowser/#/R-HSA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 15377 R-HSA-9753280 https://reactome.org/PathwayBrowser/#/R-HSA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG TAS Homo sapiens 15377 R-HSA-9753283 https://reactome.org/PathwayBrowser/#/R-HSA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 15377 R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 15377 R-HSA-9753285 https://reactome.org/PathwayBrowser/#/R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI TAS Homo sapiens 15377 R-HSA-9753632 https://reactome.org/PathwayBrowser/#/R-HSA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly TAS Homo sapiens 15377 R-HSA-9753634 https://reactome.org/PathwayBrowser/#/R-HSA-9753634 GGT dimers hydrolyse APAP-SG TAS Homo sapiens 15377 R-HSA-9753944 https://reactome.org/PathwayBrowser/#/R-HSA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys TAS Homo sapiens 15377 R-HSA-9754964 https://reactome.org/PathwayBrowser/#/R-HSA-9754964 ADA deamidates RBV TAS Homo sapiens 15377 R-HSA-9755030 https://reactome.org/PathwayBrowser/#/R-HSA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP TAS Homo sapiens 15377 R-HSA-9755078 https://reactome.org/PathwayBrowser/#/R-HSA-9755078 NT5C2 tetramer dephosphorylates RBV-MP TAS Homo sapiens 15377 R-HSA-9755244 https://reactome.org/PathwayBrowser/#/R-HSA-9755244 SARS-CoV-2 nsp3 deISGylates ISGylated IFIH1 TAS Homo sapiens 15377 R-HSA-975593 https://reactome.org/PathwayBrowser/#/R-HSA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM TAS Homo sapiens 15377 R-HSA-975594 https://reactome.org/PathwayBrowser/#/R-HSA-975594 PLB1 hydrolyses RPALM to atROL TAS Homo sapiens 15377 R-HSA-9756136 https://reactome.org/PathwayBrowser/#/R-HSA-9756136 PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV IEA Homo sapiens 15377 R-HSA-9756138 https://reactome.org/PathwayBrowser/#/R-HSA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL TAS Homo sapiens 15377 R-HSA-9756150 https://reactome.org/PathwayBrowser/#/R-HSA-9756150 PON1,3 hydrolyse 4-OH-ATVL to 4-OH-ATV IEA Homo sapiens 15377 R-HSA-9756162 https://reactome.org/PathwayBrowser/#/R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV TAS Homo sapiens 15377 R-HSA-9756169 https://reactome.org/PathwayBrowser/#/R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV TAS Homo sapiens 15377 R-HSA-9756177 https://reactome.org/PathwayBrowser/#/R-HSA-9756177 PON1,3 hydrolyse ATVL to ATV TAS Homo sapiens 15377 R-HSA-9756180 https://reactome.org/PathwayBrowser/#/R-HSA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL TAS Homo sapiens 15377 R-HSA-9757434 https://reactome.org/PathwayBrowser/#/R-HSA-9757434 Acetylsalicylic acid dissolves TAS Homo sapiens 15377 R-HSA-9758674 https://reactome.org/PathwayBrowser/#/R-HSA-9758674 CYP3A4 oxidizes PREDN,PREDL TAS Homo sapiens 15377 R-HSA-9759206 https://reactome.org/PathwayBrowser/#/R-HSA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol TAS Homo sapiens 15377 R-HSA-9759454 https://reactome.org/PathwayBrowser/#/R-HSA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells TAS Homo sapiens 15377 R-HSA-9759461 https://reactome.org/PathwayBrowser/#/R-HSA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells TAS Homo sapiens 15377 R-HSA-977324 https://reactome.org/PathwayBrowser/#/R-HSA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser TAS Homo sapiens 15377 R-HSA-9794120 https://reactome.org/PathwayBrowser/#/R-HSA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space TAS Homo sapiens 15377 R-HSA-9794572 https://reactome.org/PathwayBrowser/#/R-HSA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space TAS Homo sapiens 15377 R-HSA-9794840 https://reactome.org/PathwayBrowser/#/R-HSA-9794840 Cipro is oxidized to oxo-Cipro TAS Homo sapiens 15377 R-HSA-9817513 https://reactome.org/PathwayBrowser/#/R-HSA-9817513 AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine IEA Homo sapiens 15377 R-HSA-9820842 https://reactome.org/PathwayBrowser/#/R-HSA-9820842 AGO2:endosiRNA hydrolyzes maternal mRNA in the zygote IEA Homo sapiens 15377 R-HSA-9822311 https://reactome.org/PathwayBrowser/#/R-HSA-9822311 CCR4-NOT deadenylates mRNA in CCR4-NOT:BTG4:PABPN1L:mRNP IEA Homo sapiens 15377 R-HSA-9822335 https://reactome.org/PathwayBrowser/#/R-HSA-9822335 CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA IEA Homo sapiens 15377 R-HSA-9822437 https://reactome.org/PathwayBrowser/#/R-HSA-9822437 DIS3L2 hydrolyzes uridylated mRNA IEA Homo sapiens 15377 R-HSA-9830848 https://reactome.org/PathwayBrowser/#/R-HSA-9830848 L protein acts as a cap N7 methyltransferase to modify RSV mRNAs TAS Homo sapiens 15377 R-HSA-983144 https://reactome.org/PathwayBrowser/#/R-HSA-983144 Transport of Antigen peptide in to ER TAS Homo sapiens 15377 R-HSA-9831948 https://reactome.org/PathwayBrowser/#/R-HSA-9831948 P:PP1 dephosphorylates M2-1 TAS Homo sapiens 15377 R-HSA-983422 https://reactome.org/PathwayBrowser/#/R-HSA-983422 Disassembly of COPII coated vesicle TAS Homo sapiens 15377 R-HSA-9836585 https://reactome.org/PathwayBrowser/#/R-HSA-9836585 SUPV3L1:PNPT1 hydrolyzes mitochondrial RNA to yield 4-5 nucleotide oligoribonucleotides TAS Homo sapiens 15377 R-HSA-9836822 https://reactome.org/PathwayBrowser/#/R-HSA-9836822 REXO2 hydrolyzes 4-5 nucleotide RNAs to ribonucleotides TAS Homo sapiens 15377 R-HSA-9837354 https://reactome.org/PathwayBrowser/#/R-HSA-9837354 NUDT8 hydrolyzes CoA-SH to PPANT IEA Homo sapiens 15377 R-HSA-9837419 https://reactome.org/PathwayBrowser/#/R-HSA-9837419 PANK4 hydrolyzes PPANT to pantetheine TAS Homo sapiens 15377 R-HSA-9838004 https://reactome.org/PathwayBrowser/#/R-HSA-9838004 LONP1 degrades mitochondrial inner membrane proteins TAS Homo sapiens 15377 R-HSA-9838081 https://reactome.org/PathwayBrowser/#/R-HSA-9838081 LONP1 degrades mitochondrial matrix proteins TAS Homo sapiens 15377 R-HSA-9838289 https://reactome.org/PathwayBrowser/#/R-HSA-9838289 CLPXP degrades mitochondrial matrix proteins TAS Homo sapiens 15377 R-HSA-9839059 https://reactome.org/PathwayBrowser/#/R-HSA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) TAS Homo sapiens 15377 R-HSA-9839072 https://reactome.org/PathwayBrowser/#/R-HSA-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) TAS Homo sapiens 15377 R-HSA-9839105 https://reactome.org/PathwayBrowser/#/R-HSA-9839105 AFG3L2 degrades mitochondrial matrix proteins TAS Homo sapiens 15377 R-HSA-9839110 https://reactome.org/PathwayBrowser/#/R-HSA-9839110 HTRA2 degrades NDUFA13 (GRIM-19) TAS Homo sapiens 15377 R-HSA-9839113 https://reactome.org/PathwayBrowser/#/R-HSA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins TAS Homo sapiens 15377 R-HSA-9839146 https://reactome.org/PathwayBrowser/#/R-HSA-9839146 YME1L1 degrades mitochondrial inner membrane proteins IEA Homo sapiens 15377 R-HSA-9839751 https://reactome.org/PathwayBrowser/#/R-HSA-9839751 YME1L1 degrades mitochondrial intermembrane space proteins IEA Homo sapiens 15377 R-HSA-9840408 https://reactome.org/PathwayBrowser/#/R-HSA-9840408 OMA1 cleaves DELE1 TAS Homo sapiens 15377 R-HSA-9840795 https://reactome.org/PathwayBrowser/#/R-HSA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 TAS Homo sapiens 15377 R-HSA-9840833 https://reactome.org/PathwayBrowser/#/R-HSA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer TAS Homo sapiens 15377 R-HSA-9840884 https://reactome.org/PathwayBrowser/#/R-HSA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 TAS Homo sapiens 15377 R-HSA-9840949 https://reactome.org/PathwayBrowser/#/R-HSA-9840949 ARSA removes sulfate from SM3 TAS Homo sapiens 15377 R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 15377 R-HSA-9843721 https://reactome.org/PathwayBrowser/#/R-HSA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region TAS Homo sapiens 15377 R-HSA-9853385 https://reactome.org/PathwayBrowser/#/R-HSA-9853385 PPP1CC dephosphorylates PLK1 TAS Homo sapiens 15377 R-HSA-9861595 https://reactome.org/PathwayBrowser/#/R-HSA-9861595 Cytosolic H2O2 decarboxylates PYR to acetate TAS Homo sapiens 15377 R-HSA-9861626 https://reactome.org/PathwayBrowser/#/R-HSA-9861626 SIRT4 cleaves lipoyl from DLAT TAS Homo sapiens 15377 R-HSA-9861725 https://reactome.org/PathwayBrowser/#/R-HSA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 TAS Homo sapiens 15377 R-HSA-9861745 https://reactome.org/PathwayBrowser/#/R-HSA-9861745 Mitochondrial H2O2 decarboxylates PYR to acetate TAS Homo sapiens 15377 R-HSA-9863531 https://reactome.org/PathwayBrowser/#/R-HSA-9863531 GS-MCA spontaneously hydrolyzes TAS Homo sapiens 15377 R-HSA-997309 https://reactome.org/PathwayBrowser/#/R-HSA-997309 Dephosphorylation of STAT1 by SHP2 TAS Homo sapiens 15377 R-HSA-997311 https://reactome.org/PathwayBrowser/#/R-HSA-997311 Dephosphorylation of TYK2 by PTP1B TAS Homo sapiens 15377 R-HSA-997314 https://reactome.org/PathwayBrowser/#/R-HSA-997314 Dephosphorylation of JAK1 by SHP1 TAS Homo sapiens 15377 R-HSA-997326 https://reactome.org/PathwayBrowser/#/R-HSA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP TAS Homo sapiens 15377 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 15377 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 15377 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 15377 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 15377 R-MMU-109415 https://reactome.org/PathwayBrowser/#/R-MMU-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Mus musculus 15377 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 15377 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 15377 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 15377 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 15377 R-MMU-111742 https://reactome.org/PathwayBrowser/#/R-MMU-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 15377 R-MMU-111751 https://reactome.org/PathwayBrowser/#/R-MMU-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 15377 R-MMU-111804 https://reactome.org/PathwayBrowser/#/R-MMU-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 15377 R-MMU-111879 https://reactome.org/PathwayBrowser/#/R-MMU-111879 PIP2 hydrolysis IEA Mus musculus 15377 R-MMU-111883 https://reactome.org/PathwayBrowser/#/R-MMU-111883 Hydrolysis of phosphatidylcholine IEA Mus musculus 15377 R-MMU-111955 https://reactome.org/PathwayBrowser/#/R-MMU-111955 cAMP hydrolysis by Cam-PDE 1 IEA Mus musculus 15377 R-MMU-111962 https://reactome.org/PathwayBrowser/#/R-MMU-111962 PDE4A,C,D hydrolyse cAMP IEA Mus musculus 15377 R-MMU-112037 https://reactome.org/PathwayBrowser/#/R-MMU-112037 Inactivation of PLC beta IEA Mus musculus 15377 R-MMU-113503 https://reactome.org/PathwayBrowser/#/R-MMU-113503 PP2A mediated localization of RB1 protein in chromatin IEA Mus musculus 15377 R-MMU-1169192 https://reactome.org/PathwayBrowser/#/R-MMU-1169192 PTP1B dephosphorylates GHR IEA Mus musculus 15377 R-MMU-1183128 https://reactome.org/PathwayBrowser/#/R-MMU-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Mus musculus 15377 R-MMU-1237045 https://reactome.org/PathwayBrowser/#/R-MMU-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Mus musculus 15377 R-MMU-1237047 https://reactome.org/PathwayBrowser/#/R-MMU-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Mus musculus 15377 R-MMU-1237059 https://reactome.org/PathwayBrowser/#/R-MMU-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Mus musculus 15377 R-MMU-1237081 https://reactome.org/PathwayBrowser/#/R-MMU-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Mus musculus 15377 R-MMU-1237129 https://reactome.org/PathwayBrowser/#/R-MMU-1237129 Acireductone is created IEA Mus musculus 15377 R-MMU-1247910 https://reactome.org/PathwayBrowser/#/R-MMU-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Mus musculus 15377 R-MMU-1247935 https://reactome.org/PathwayBrowser/#/R-MMU-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Mus musculus 15377 R-MMU-1363274 https://reactome.org/PathwayBrowser/#/R-MMU-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Mus musculus 15377 R-MMU-1363276 https://reactome.org/PathwayBrowser/#/R-MMU-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Mus musculus 15377 R-MMU-1369028 https://reactome.org/PathwayBrowser/#/R-MMU-1369028 ABCAs mediate lipid efflux IEA Mus musculus 15377 R-MMU-1369052 https://reactome.org/PathwayBrowser/#/R-MMU-1369052 ABCAs mediate lipid influx IEA Mus musculus 15377 R-MMU-1369065 https://reactome.org/PathwayBrowser/#/R-MMU-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Mus musculus 15377 R-MMU-139906 https://reactome.org/PathwayBrowser/#/R-MMU-139906 Activation of BAD by calcineurin IEA Mus musculus 15377 R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 15377 R-MMU-140359 https://reactome.org/PathwayBrowser/#/R-MMU-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Mus musculus 15377 R-MMU-141186 https://reactome.org/PathwayBrowser/#/R-MMU-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Mus musculus 15377 R-MMU-141200 https://reactome.org/PathwayBrowser/#/R-MMU-141200 MAOB:FAD oxidatively deaminates of PEA IEA Mus musculus 15377 R-MMU-141202 https://reactome.org/PathwayBrowser/#/R-MMU-141202 MAOB:FAD oxidatively deaminates TYR IEA Mus musculus 15377 R-MMU-141341 https://reactome.org/PathwayBrowser/#/R-MMU-141341 SMOX-3 oxidises SPN to SPM IEA Mus musculus 15377 R-MMU-141348 https://reactome.org/PathwayBrowser/#/R-MMU-141348 PAO:FAD oxidises NASPM to PTCN IEA Mus musculus 15377 R-MMU-141351 https://reactome.org/PathwayBrowser/#/R-MMU-141351 PAOX:FAD oxidises NASPN to SPM IEA Mus musculus 15377 R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 15377 R-MMU-1454916 https://reactome.org/PathwayBrowser/#/R-MMU-1454916 The ABCC family mediates organic anion transport IEA Mus musculus 15377 R-MMU-1454928 https://reactome.org/PathwayBrowser/#/R-MMU-1454928 ABCG4 may mediate cholesterol efflux IEA Mus musculus 15377 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 15377 R-MMU-1467466 https://reactome.org/PathwayBrowser/#/R-MMU-1467466 ABCA4 mediates atRAL transport IEA Mus musculus 15377 R-MMU-1474146 https://reactome.org/PathwayBrowser/#/R-MMU-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Mus musculus 15377 R-MMU-1475017 https://reactome.org/PathwayBrowser/#/R-MMU-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Mus musculus 15377 R-MMU-1475022 https://reactome.org/PathwayBrowser/#/R-MMU-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Mus musculus 15377 R-MMU-1475025 https://reactome.org/PathwayBrowser/#/R-MMU-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Mus musculus 15377 R-MMU-1475026 https://reactome.org/PathwayBrowser/#/R-MMU-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Mus musculus 15377 R-MMU-1475028 https://reactome.org/PathwayBrowser/#/R-MMU-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Mus musculus 15377 R-MMU-1475032 https://reactome.org/PathwayBrowser/#/R-MMU-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Mus musculus 15377 R-MMU-1475435 https://reactome.org/PathwayBrowser/#/R-MMU-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Mus musculus 15377 R-MMU-1475436 https://reactome.org/PathwayBrowser/#/R-MMU-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Mus musculus 15377 R-MMU-1482543 https://reactome.org/PathwayBrowser/#/R-MMU-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Mus musculus 15377 R-MMU-1482545 https://reactome.org/PathwayBrowser/#/R-MMU-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Mus musculus 15377 R-MMU-1482571 https://reactome.org/PathwayBrowser/#/R-MMU-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Mus musculus 15377 R-MMU-1482604 https://reactome.org/PathwayBrowser/#/R-MMU-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Mus musculus 15377 R-MMU-1482612 https://reactome.org/PathwayBrowser/#/R-MMU-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 15377 R-MMU-1482629 https://reactome.org/PathwayBrowser/#/R-MMU-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Mus musculus 15377 R-MMU-1482656 https://reactome.org/PathwayBrowser/#/R-MMU-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Mus musculus 15377 R-MMU-1482679 https://reactome.org/PathwayBrowser/#/R-MMU-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Mus musculus 15377 R-MMU-1482685 https://reactome.org/PathwayBrowser/#/R-MMU-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 15377 R-MMU-1482696 https://reactome.org/PathwayBrowser/#/R-MMU-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Mus musculus 15377 R-MMU-1482745 https://reactome.org/PathwayBrowser/#/R-MMU-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Mus musculus 15377 R-MMU-1482759 https://reactome.org/PathwayBrowser/#/R-MMU-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Mus musculus 15377 R-MMU-1482771 https://reactome.org/PathwayBrowser/#/R-MMU-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Mus musculus 15377 R-MMU-1482776 https://reactome.org/PathwayBrowser/#/R-MMU-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Mus musculus 15377 R-MMU-1482777 https://reactome.org/PathwayBrowser/#/R-MMU-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Mus musculus 15377 R-MMU-1482811 https://reactome.org/PathwayBrowser/#/R-MMU-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Mus musculus 15377 R-MMU-1482816 https://reactome.org/PathwayBrowser/#/R-MMU-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Mus musculus 15377 R-MMU-1482825 https://reactome.org/PathwayBrowser/#/R-MMU-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Mus musculus 15377 R-MMU-1482827 https://reactome.org/PathwayBrowser/#/R-MMU-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Mus musculus 15377 R-MMU-1482828 https://reactome.org/PathwayBrowser/#/R-MMU-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Mus musculus 15377 R-MMU-1482847 https://reactome.org/PathwayBrowser/#/R-MMU-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Mus musculus 15377 R-MMU-1482856 https://reactome.org/PathwayBrowser/#/R-MMU-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Mus musculus 15377 R-MMU-1482862 https://reactome.org/PathwayBrowser/#/R-MMU-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Mus musculus 15377 R-MMU-1482868 https://reactome.org/PathwayBrowser/#/R-MMU-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Mus musculus 15377 R-MMU-1482884 https://reactome.org/PathwayBrowser/#/R-MMU-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Mus musculus 15377 R-MMU-1482887 https://reactome.org/PathwayBrowser/#/R-MMU-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Mus musculus 15377 R-MMU-1482892 https://reactome.org/PathwayBrowser/#/R-MMU-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Mus musculus 15377 R-MMU-1482897 https://reactome.org/PathwayBrowser/#/R-MMU-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Mus musculus 15377 R-MMU-1482900 https://reactome.org/PathwayBrowser/#/R-MMU-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Mus musculus 15377 R-MMU-1482907 https://reactome.org/PathwayBrowser/#/R-MMU-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Mus musculus 15377 R-MMU-1482920 https://reactome.org/PathwayBrowser/#/R-MMU-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Mus musculus 15377 R-MMU-1482932 https://reactome.org/PathwayBrowser/#/R-MMU-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Mus musculus 15377 R-MMU-1483096 https://reactome.org/PathwayBrowser/#/R-MMU-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Mus musculus 15377 R-MMU-1483112 https://reactome.org/PathwayBrowser/#/R-MMU-1483112 GPCho is hydrolyzed to Cho and G3P by Gpcpd1 TAS Mus musculus 15377 R-MMU-1483159 https://reactome.org/PathwayBrowser/#/R-MMU-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Mus musculus 15377 R-MMU-1483182 https://reactome.org/PathwayBrowser/#/R-MMU-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Mus musculus 15377 R-MMU-1483203 https://reactome.org/PathwayBrowser/#/R-MMU-1483203 PA is dephosphorylated to DAG by LPIN IEA Mus musculus 15377 R-MMU-1483231 https://reactome.org/PathwayBrowser/#/R-MMU-1483231 GPETA is hydrolyzed to ETA and G3P by Gpcpd1 TAS Mus musculus 15377 R-MMU-156526 https://reactome.org/PathwayBrowser/#/R-MMU-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Mus musculus 15377 R-MMU-159425 https://reactome.org/PathwayBrowser/#/R-MMU-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 15377 R-MMU-159752 https://reactome.org/PathwayBrowser/#/R-MMU-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Mus musculus 15377 R-MMU-159761 https://reactome.org/PathwayBrowser/#/R-MMU-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Mus musculus 15377 R-MMU-159795 https://reactome.org/PathwayBrowser/#/R-MMU-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Mus musculus 15377 R-MMU-159803 https://reactome.org/PathwayBrowser/#/R-MMU-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Mus musculus 15377 R-MMU-159819 https://reactome.org/PathwayBrowser/#/R-MMU-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Mus musculus 15377 R-MMU-159826 https://reactome.org/PathwayBrowser/#/R-MMU-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Mus musculus 15377 R-MMU-1602368 https://reactome.org/PathwayBrowser/#/R-MMU-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Mus musculus 15377 R-MMU-1602374 https://reactome.org/PathwayBrowser/#/R-MMU-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Mus musculus 15377 R-MMU-1602377 https://reactome.org/PathwayBrowser/#/R-MMU-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Mus musculus 15377 R-MMU-1602398 https://reactome.org/PathwayBrowser/#/R-MMU-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Mus musculus 15377 R-MMU-1602399 https://reactome.org/PathwayBrowser/#/R-MMU-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Mus musculus 15377 R-MMU-1602417 https://reactome.org/PathwayBrowser/#/R-MMU-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Mus musculus 15377 R-MMU-1602446 https://reactome.org/PathwayBrowser/#/R-MMU-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Mus musculus 15377 R-MMU-1605591 https://reactome.org/PathwayBrowser/#/R-MMU-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Mus musculus 15377 R-MMU-1605595 https://reactome.org/PathwayBrowser/#/R-MMU-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Mus musculus 15377 R-MMU-1605624 https://reactome.org/PathwayBrowser/#/R-MMU-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Mus musculus 15377 R-MMU-1605632 https://reactome.org/PathwayBrowser/#/R-MMU-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Mus musculus 15377 R-MMU-1605723 https://reactome.org/PathwayBrowser/#/R-MMU-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Mus musculus 15377 R-MMU-1605724 https://reactome.org/PathwayBrowser/#/R-MMU-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Mus musculus 15377 R-MMU-1605736 https://reactome.org/PathwayBrowser/#/R-MMU-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Mus musculus 15377 R-MMU-1605768 https://reactome.org/PathwayBrowser/#/R-MMU-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Mus musculus 15377 R-MMU-1605797 https://reactome.org/PathwayBrowser/#/R-MMU-1605797 SMPD1 hydrolyzes SPHM IEA Mus musculus 15377 R-MMU-1606273 https://reactome.org/PathwayBrowser/#/R-MMU-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Mus musculus 15377 R-MMU-1606288 https://reactome.org/PathwayBrowser/#/R-MMU-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Mus musculus 15377 R-MMU-1606312 https://reactome.org/PathwayBrowser/#/R-MMU-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Mus musculus 15377 R-MMU-1606564 https://reactome.org/PathwayBrowser/#/R-MMU-1606564 GALC hydrolyzes GalCer IEA Mus musculus 15377 R-MMU-1606583 https://reactome.org/PathwayBrowser/#/R-MMU-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Mus musculus 15377 R-MMU-1606602 https://reactome.org/PathwayBrowser/#/R-MMU-1606602 ASAH1 hydrolyzes ceramide IEA Mus musculus 15377 R-MMU-1606789 https://reactome.org/PathwayBrowser/#/R-MMU-1606789 ARSB hydrolyses DS IEA Mus musculus 15377 R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 15377 R-MMU-1606839 https://reactome.org/PathwayBrowser/#/R-MMU-1606839 ARSC hydrolyzes steroid sulfates IEA Mus musculus 15377 R-MMU-1614524 https://reactome.org/PathwayBrowser/#/R-MMU-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Mus musculus 15377 R-MMU-1614544 https://reactome.org/PathwayBrowser/#/R-MMU-1614544 Sulfite is oxidized to sulfate IEA Mus musculus 15377 R-MMU-1614583 https://reactome.org/PathwayBrowser/#/R-MMU-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Mus musculus 15377 R-MMU-1614605 https://reactome.org/PathwayBrowser/#/R-MMU-1614605 Persulfide sulfur is dioxygenated IEA Mus musculus 15377 R-MMU-1614614 https://reactome.org/PathwayBrowser/#/R-MMU-1614614 Cysteine is degraded to serine and H2S IEA Mus musculus 15377 R-MMU-1614631 https://reactome.org/PathwayBrowser/#/R-MMU-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Mus musculus 15377 R-MMU-162425 https://reactome.org/PathwayBrowser/#/R-MMU-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Mus musculus 15377 R-MMU-162729 https://reactome.org/PathwayBrowser/#/R-MMU-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Mus musculus 15377 R-MMU-162857 https://reactome.org/PathwayBrowser/#/R-MMU-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Mus musculus 15377 R-MMU-1630304 https://reactome.org/PathwayBrowser/#/R-MMU-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Mus musculus 15377 R-MMU-1630306 https://reactome.org/PathwayBrowser/#/R-MMU-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Mus musculus 15377 R-MMU-163120 https://reactome.org/PathwayBrowser/#/R-MMU-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Mus musculus 15377 R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 15377 R-MMU-1638032 https://reactome.org/PathwayBrowser/#/R-MMU-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Mus musculus 15377 R-MMU-1638053 https://reactome.org/PathwayBrowser/#/R-MMU-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Mus musculus 15377 R-MMU-163820 https://reactome.org/PathwayBrowser/#/R-MMU-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Mus musculus 15377 R-MMU-1638821 https://reactome.org/PathwayBrowser/#/R-MMU-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Mus musculus 15377 R-MMU-1640164 https://reactome.org/PathwayBrowser/#/R-MMU-1640164 ENPP7 hydrolyzes sphingomyelin IEA Mus musculus 15377 R-MMU-164832 https://reactome.org/PathwayBrowser/#/R-MMU-164832 ATPase synthesizes ATP IEA Mus musculus 15377 R-MMU-1655453 https://reactome.org/PathwayBrowser/#/R-MMU-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Mus musculus 15377 R-MMU-1667005 https://reactome.org/PathwayBrowser/#/R-MMU-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Mus musculus 15377 R-MMU-1675795 https://reactome.org/PathwayBrowser/#/R-MMU-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Mus musculus 15377 R-MMU-1675824 https://reactome.org/PathwayBrowser/#/R-MMU-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Mus musculus 15377 R-MMU-1675836 https://reactome.org/PathwayBrowser/#/R-MMU-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Mus musculus 15377 R-MMU-1675949 https://reactome.org/PathwayBrowser/#/R-MMU-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Mus musculus 15377 R-MMU-1675988 https://reactome.org/PathwayBrowser/#/R-MMU-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Mus musculus 15377 R-MMU-1675994 https://reactome.org/PathwayBrowser/#/R-MMU-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Mus musculus 15377 R-MMU-1676005 https://reactome.org/PathwayBrowser/#/R-MMU-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Mus musculus 15377 R-MMU-1676020 https://reactome.org/PathwayBrowser/#/R-MMU-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Mus musculus 15377 R-MMU-1676065 https://reactome.org/PathwayBrowser/#/R-MMU-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Mus musculus 15377 R-MMU-1676105 https://reactome.org/PathwayBrowser/#/R-MMU-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Mus musculus 15377 R-MMU-1676114 https://reactome.org/PathwayBrowser/#/R-MMU-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Mus musculus 15377 R-MMU-1676124 https://reactome.org/PathwayBrowser/#/R-MMU-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Mus musculus 15377 R-MMU-1676141 https://reactome.org/PathwayBrowser/#/R-MMU-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Mus musculus 15377 R-MMU-1676149 https://reactome.org/PathwayBrowser/#/R-MMU-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Mus musculus 15377 R-MMU-1676162 https://reactome.org/PathwayBrowser/#/R-MMU-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Mus musculus 15377 R-MMU-1676164 https://reactome.org/PathwayBrowser/#/R-MMU-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Mus musculus 15377 R-MMU-1676174 https://reactome.org/PathwayBrowser/#/R-MMU-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Mus musculus 15377 R-MMU-1676177 https://reactome.org/PathwayBrowser/#/R-MMU-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Mus musculus 15377 R-MMU-1676203 https://reactome.org/PathwayBrowser/#/R-MMU-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Mus musculus 15377 R-MMU-1676204 https://reactome.org/PathwayBrowser/#/R-MMU-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Mus musculus 15377 R-MMU-1678650 https://reactome.org/PathwayBrowser/#/R-MMU-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Mus musculus 15377 R-MMU-1678708 https://reactome.org/PathwayBrowser/#/R-MMU-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Mus musculus 15377 R-MMU-1678716 https://reactome.org/PathwayBrowser/#/R-MMU-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Mus musculus 15377 R-MMU-1678742 https://reactome.org/PathwayBrowser/#/R-MMU-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Mus musculus 15377 R-MMU-1678854 https://reactome.org/PathwayBrowser/#/R-MMU-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Mus musculus 15377 R-MMU-170153 https://reactome.org/PathwayBrowser/#/R-MMU-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Mus musculus 15377 R-MMU-170158 https://reactome.org/PathwayBrowser/#/R-MMU-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Mus musculus 15377 R-MMU-170161 https://reactome.org/PathwayBrowser/#/R-MMU-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Mus musculus 15377 R-MMU-173597 https://reactome.org/PathwayBrowser/#/R-MMU-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Mus musculus 15377 R-MMU-173739 https://reactome.org/PathwayBrowser/#/R-MMU-173739 Spontaneous hydrolysis of C3 thioester IEA Mus musculus 15377 R-MMU-174110 https://reactome.org/PathwayBrowser/#/R-MMU-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Mus musculus 15377 R-MMU-174124 https://reactome.org/PathwayBrowser/#/R-MMU-174124 Dephosphorylation of phospho-Cdh1 IEA Mus musculus 15377 R-MMU-174391 https://reactome.org/PathwayBrowser/#/R-MMU-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Mus musculus 15377 R-MMU-174401 https://reactome.org/PathwayBrowser/#/R-MMU-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Mus musculus 15377 R-MMU-174438 https://reactome.org/PathwayBrowser/#/R-MMU-174438 Formation of the Flap Intermediate on the C-strand IEA Mus musculus 15377 R-MMU-174439 https://reactome.org/PathwayBrowser/#/R-MMU-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Mus musculus 15377 R-MMU-176606 https://reactome.org/PathwayBrowser/#/R-MMU-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Mus musculus 15377 R-MMU-177923 https://reactome.org/PathwayBrowser/#/R-MMU-177923 Sustained activation of SRC kinase by SHP2 IEA Mus musculus 15377 R-MMU-177924 https://reactome.org/PathwayBrowser/#/R-MMU-177924 Dephosphorylation of Gab1 by SHP2 IEA Mus musculus 15377 R-MMU-177926 https://reactome.org/PathwayBrowser/#/R-MMU-177926 Dephosphorylation of PAG by SHP2 IEA Mus musculus 15377 R-MMU-177935 https://reactome.org/PathwayBrowser/#/R-MMU-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Mus musculus 15377 R-MMU-1793182 https://reactome.org/PathwayBrowser/#/R-MMU-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Mus musculus 15377 R-MMU-1793186 https://reactome.org/PathwayBrowser/#/R-MMU-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Mus musculus 15377 R-MMU-1793207 https://reactome.org/PathwayBrowser/#/R-MMU-1793207 ARSB hydrolyses C4S/C6S chains IEA Mus musculus 15377 R-MMU-1793209 https://reactome.org/PathwayBrowser/#/R-MMU-1793209 HYAL1 hydrolyses Chondroitin chains IEA Mus musculus 15377 R-MMU-1855154 https://reactome.org/PathwayBrowser/#/R-MMU-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 15377 R-MMU-1855159 https://reactome.org/PathwayBrowser/#/R-MMU-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Mus musculus 15377 R-MMU-1855163 https://reactome.org/PathwayBrowser/#/R-MMU-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Mus musculus 15377 R-MMU-1855165 https://reactome.org/PathwayBrowser/#/R-MMU-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 15377 R-MMU-1855166 https://reactome.org/PathwayBrowser/#/R-MMU-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Mus musculus 15377 R-MMU-1855171 https://reactome.org/PathwayBrowser/#/R-MMU-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Mus musculus 15377 R-MMU-1855174 https://reactome.org/PathwayBrowser/#/R-MMU-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Mus musculus 15377 R-MMU-1855177 https://reactome.org/PathwayBrowser/#/R-MMU-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Mus musculus 15377 R-MMU-1855180 https://reactome.org/PathwayBrowser/#/R-MMU-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Mus musculus 15377 R-MMU-1855198 https://reactome.org/PathwayBrowser/#/R-MMU-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 15377 R-MMU-1855200 https://reactome.org/PathwayBrowser/#/R-MMU-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Mus musculus 15377 R-MMU-1855202 https://reactome.org/PathwayBrowser/#/R-MMU-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Mus musculus 15377 R-MMU-1855205 https://reactome.org/PathwayBrowser/#/R-MMU-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Mus musculus 15377 R-MMU-1855208 https://reactome.org/PathwayBrowser/#/R-MMU-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Mus musculus 15377 R-MMU-1855210 https://reactome.org/PathwayBrowser/#/R-MMU-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 15377 R-MMU-1855211 https://reactome.org/PathwayBrowser/#/R-MMU-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 15377 R-MMU-1855213 https://reactome.org/PathwayBrowser/#/R-MMU-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Mus musculus 15377 R-MMU-1855214 https://reactome.org/PathwayBrowser/#/R-MMU-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Mus musculus 15377 R-MMU-1855218 https://reactome.org/PathwayBrowser/#/R-MMU-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Mus musculus 15377 R-MMU-1855219 https://reactome.org/PathwayBrowser/#/R-MMU-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Mus musculus 15377 R-MMU-1855221 https://reactome.org/PathwayBrowser/#/R-MMU-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Mus musculus 15377 R-MMU-1855222 https://reactome.org/PathwayBrowser/#/R-MMU-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Mus musculus 15377 R-MMU-1855225 https://reactome.org/PathwayBrowser/#/R-MMU-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Mus musculus 15377 R-MMU-1855232 https://reactome.org/PathwayBrowser/#/R-MMU-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Mus musculus 15377 R-MMU-1861788 https://reactome.org/PathwayBrowser/#/R-MMU-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Mus musculus 15377 R-MMU-188979 https://reactome.org/PathwayBrowser/#/R-MMU-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Mus musculus 15377 R-MMU-189053 https://reactome.org/PathwayBrowser/#/R-MMU-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Mus musculus 15377 R-MMU-189062 https://reactome.org/PathwayBrowser/#/R-MMU-189062 lactose + H2O => D-glucose + D-galactose IEA Mus musculus 15377 R-MMU-189069 https://reactome.org/PathwayBrowser/#/R-MMU-189069 sucrose + H2O => glucose + fructose IEA Mus musculus 15377 R-MMU-189102 https://reactome.org/PathwayBrowser/#/R-MMU-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Mus musculus 15377 R-MMU-189398 https://reactome.org/PathwayBrowser/#/R-MMU-189398 HMOX1 dimer, HMOX2 cleave heme IEA Mus musculus 15377 R-MMU-189406 https://reactome.org/PathwayBrowser/#/R-MMU-189406 4 PBGs bind to form HMB IEA Mus musculus 15377 R-MMU-189421 https://reactome.org/PathwayBrowser/#/R-MMU-189421 CPO transforms COPRO3 to PPGEN9 IEA Mus musculus 15377 R-MMU-189439 https://reactome.org/PathwayBrowser/#/R-MMU-189439 ALAD condenses 2 dALAs to form PBG IEA Mus musculus 15377 R-MMU-189488 https://reactome.org/PathwayBrowser/#/R-MMU-189488 UROS transforms HMB to URO3 IEA Mus musculus 15377 R-MMU-191101 https://reactome.org/PathwayBrowser/#/R-MMU-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Mus musculus 15377 R-MMU-191108 https://reactome.org/PathwayBrowser/#/R-MMU-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Mus musculus 15377 R-MMU-191114 https://reactome.org/PathwayBrowser/#/R-MMU-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Mus musculus 15377 R-MMU-191116 https://reactome.org/PathwayBrowser/#/R-MMU-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Mus musculus 15377 R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 15377 R-MMU-191323 https://reactome.org/PathwayBrowser/#/R-MMU-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Mus musculus 15377 R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 15377 R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 15377 R-MMU-191999 https://reactome.org/PathwayBrowser/#/R-MMU-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Mus musculus 15377 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 15377 R-MMU-192054 https://reactome.org/PathwayBrowser/#/R-MMU-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Mus musculus 15377 R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 15377 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 15377 R-MMU-192123 https://reactome.org/PathwayBrowser/#/R-MMU-192123 CYP27A1 27-hydroxylates CHOL IEA Mus musculus 15377 R-MMU-192157 https://reactome.org/PathwayBrowser/#/R-MMU-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Mus musculus 15377 R-MMU-192178 https://reactome.org/PathwayBrowser/#/R-MMU-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Mus musculus 15377 R-MMU-192331 https://reactome.org/PathwayBrowser/#/R-MMU-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Mus musculus 15377 R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 15377 R-MMU-192422 https://reactome.org/PathwayBrowser/#/R-MMU-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Mus musculus 15377 R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 15377 R-MMU-192430 https://reactome.org/PathwayBrowser/#/R-MMU-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 15377 R-MMU-192434 https://reactome.org/PathwayBrowser/#/R-MMU-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Mus musculus 15377 R-MMU-192475 https://reactome.org/PathwayBrowser/#/R-MMU-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Mus musculus 15377 R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 15377 R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 15377 R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 15377 R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 15377 R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 15377 R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 15377 R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 15377 R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 15377 R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 15377 R-MMU-193362 https://reactome.org/PathwayBrowser/#/R-MMU-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Mus musculus 15377 R-MMU-193385 https://reactome.org/PathwayBrowser/#/R-MMU-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Mus musculus 15377 R-MMU-193393 https://reactome.org/PathwayBrowser/#/R-MMU-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Mus musculus 15377 R-MMU-193460 https://reactome.org/PathwayBrowser/#/R-MMU-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Mus musculus 15377 R-MMU-193535 https://reactome.org/PathwayBrowser/#/R-MMU-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Mus musculus 15377 R-MMU-193709 https://reactome.org/PathwayBrowser/#/R-MMU-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Mus musculus 15377 R-MMU-193711 https://reactome.org/PathwayBrowser/#/R-MMU-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 15377 R-MMU-193713 https://reactome.org/PathwayBrowser/#/R-MMU-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Mus musculus 15377 R-MMU-193719 https://reactome.org/PathwayBrowser/#/R-MMU-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 15377 R-MMU-193727 https://reactome.org/PathwayBrowser/#/R-MMU-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 15377 R-MMU-193737 https://reactome.org/PathwayBrowser/#/R-MMU-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Mus musculus 15377 R-MMU-193743 https://reactome.org/PathwayBrowser/#/R-MMU-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 15377 R-MMU-193766 https://reactome.org/PathwayBrowser/#/R-MMU-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 15377 R-MMU-193780 https://reactome.org/PathwayBrowser/#/R-MMU-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Mus musculus 15377 R-MMU-193787 https://reactome.org/PathwayBrowser/#/R-MMU-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Mus musculus 15377 R-MMU-193792 https://reactome.org/PathwayBrowser/#/R-MMU-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Mus musculus 15377 R-MMU-193845 https://reactome.org/PathwayBrowser/#/R-MMU-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Mus musculus 15377 R-MMU-193964 https://reactome.org/PathwayBrowser/#/R-MMU-193964 CYP21A2 21-hydroxylates PROG IEA Mus musculus 15377 R-MMU-193965 https://reactome.org/PathwayBrowser/#/R-MMU-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Mus musculus 15377 R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 15377 R-MMU-193995 https://reactome.org/PathwayBrowser/#/R-MMU-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Mus musculus 15377 R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 15377 R-MMU-194017 https://reactome.org/PathwayBrowser/#/R-MMU-194017 CYP11B2 oxidises 11DCORST to CORST IEA Mus musculus 15377 R-MMU-194641 https://reactome.org/PathwayBrowser/#/R-MMU-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15377 R-MMU-194669 https://reactome.org/PathwayBrowser/#/R-MMU-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15377 R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 15377 R-MMU-195664 https://reactome.org/PathwayBrowser/#/R-MMU-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Mus musculus 15377 R-MMU-196950 https://reactome.org/PathwayBrowser/#/R-MMU-196950 2xTRAP hydrolyzes FMN to RIB IEA Mus musculus 15377 R-MMU-196955 https://reactome.org/PathwayBrowser/#/R-MMU-196955 2xENPP1 hydrolyzes FAD to FMN IEA Mus musculus 15377 R-MMU-197271 https://reactome.org/PathwayBrowser/#/R-MMU-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Mus musculus 15377 R-MMU-199425 https://reactome.org/PathwayBrowser/#/R-MMU-199425 PHLPP dephosphorylates S473 in AKT IEA Mus musculus 15377 R-MMU-199456 https://reactome.org/PathwayBrowser/#/R-MMU-199456 PTEN dephosphorylates PIP3 IEA Mus musculus 15377 R-MMU-199959 https://reactome.org/PathwayBrowser/#/R-MMU-199959 ERKs are inactivated by protein phosphatase 2A IEA Mus musculus 15377 R-MMU-2002466 https://reactome.org/PathwayBrowser/#/R-MMU-2002466 Formation of allysine by LOX IEA Mus musculus 15377 R-MMU-200661 https://reactome.org/PathwayBrowser/#/R-MMU-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Mus musculus 15377 R-MMU-200740 https://reactome.org/PathwayBrowser/#/R-MMU-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Mus musculus 15377 R-MMU-201035 https://reactome.org/PathwayBrowser/#/R-MMU-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Mus musculus 15377 R-MMU-201790 https://reactome.org/PathwayBrowser/#/R-MMU-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Mus musculus 15377 R-MMU-202214 https://reactome.org/PathwayBrowser/#/R-MMU-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Mus musculus 15377 R-MMU-2022368 https://reactome.org/PathwayBrowser/#/R-MMU-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Mus musculus 15377 R-MMU-202237 https://reactome.org/PathwayBrowser/#/R-MMU-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Mus musculus 15377 R-MMU-2022378 https://reactome.org/PathwayBrowser/#/R-MMU-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Mus musculus 15377 R-MMU-2022379 https://reactome.org/PathwayBrowser/#/R-MMU-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Mus musculus 15377 R-MMU-2022381 https://reactome.org/PathwayBrowser/#/R-MMU-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 15377 R-MMU-2022383 https://reactome.org/PathwayBrowser/#/R-MMU-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 15377 R-MMU-2022396 https://reactome.org/PathwayBrowser/#/R-MMU-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Mus musculus 15377 R-MMU-2022398 https://reactome.org/PathwayBrowser/#/R-MMU-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Mus musculus 15377 R-MMU-2022399 https://reactome.org/PathwayBrowser/#/R-MMU-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Mus musculus 15377 R-MMU-2022403 https://reactome.org/PathwayBrowser/#/R-MMU-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Mus musculus 15377 R-MMU-2022405 https://reactome.org/PathwayBrowser/#/R-MMU-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 15377 R-MMU-2022411 https://reactome.org/PathwayBrowser/#/R-MMU-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 15377 R-MMU-2022412 https://reactome.org/PathwayBrowser/#/R-MMU-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Mus musculus 15377 R-MMU-2022887 https://reactome.org/PathwayBrowser/#/R-MMU-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Mus musculus 15377 R-MMU-2023971 https://reactome.org/PathwayBrowser/#/R-MMU-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 15377 R-MMU-2023973 https://reactome.org/PathwayBrowser/#/R-MMU-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 15377 R-MMU-202407 https://reactome.org/PathwayBrowser/#/R-MMU-202407 PLC-gamma1 hydrolyses PIP2 IEA Mus musculus 15377 R-MMU-2028294 https://reactome.org/PathwayBrowser/#/R-MMU-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Mus musculus 15377 R-MMU-2029468 https://reactome.org/PathwayBrowser/#/R-MMU-2029468 Conversion of PA into DAG by PAP-1 IEA Mus musculus 15377 R-MMU-2029471 https://reactome.org/PathwayBrowser/#/R-MMU-2029471 Hydrolysis of PC to PA by PLD IEA Mus musculus 15377 R-MMU-2029475 https://reactome.org/PathwayBrowser/#/R-MMU-2029475 Production of AA by iPLA2 upon FCGR activation IEA Mus musculus 15377 R-MMU-203797 https://reactome.org/PathwayBrowser/#/R-MMU-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Mus musculus 15377 R-MMU-204169 https://reactome.org/PathwayBrowser/#/R-MMU-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Mus musculus 15377 R-MMU-2046083 https://reactome.org/PathwayBrowser/#/R-MMU-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Mus musculus 15377 R-MMU-2046084 https://reactome.org/PathwayBrowser/#/R-MMU-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Mus musculus 15377 R-MMU-2046088 https://reactome.org/PathwayBrowser/#/R-MMU-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Mus musculus 15377 R-MMU-2046089 https://reactome.org/PathwayBrowser/#/R-MMU-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Mus musculus 15377 R-MMU-2046090 https://reactome.org/PathwayBrowser/#/R-MMU-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 15377 R-MMU-2046092 https://reactome.org/PathwayBrowser/#/R-MMU-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Mus musculus 15377 R-MMU-2046094 https://reactome.org/PathwayBrowser/#/R-MMU-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Mus musculus 15377 R-MMU-2046095 https://reactome.org/PathwayBrowser/#/R-MMU-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Mus musculus 15377 R-MMU-2046096 https://reactome.org/PathwayBrowser/#/R-MMU-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Mus musculus 15377 R-MMU-2046097 https://reactome.org/PathwayBrowser/#/R-MMU-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 15377 R-MMU-2046100 https://reactome.org/PathwayBrowser/#/R-MMU-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Mus musculus 15377 R-MMU-204662 https://reactome.org/PathwayBrowser/#/R-MMU-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Mus musculus 15377 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 15377 R-MMU-2065357 https://reactome.org/PathwayBrowser/#/R-MMU-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Mus musculus 15377 R-MMU-2066778 https://reactome.org/PathwayBrowser/#/R-MMU-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Mus musculus 15377 R-MMU-2066779 https://reactome.org/PathwayBrowser/#/R-MMU-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Mus musculus 15377 R-MMU-2090037 https://reactome.org/PathwayBrowser/#/R-MMU-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Mus musculus 15377 R-MMU-2090038 https://reactome.org/PathwayBrowser/#/R-MMU-2090038 NAGLU hydrolyses heparan chain(2) IEA Mus musculus 15377 R-MMU-2090043 https://reactome.org/PathwayBrowser/#/R-MMU-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Mus musculus 15377 R-MMU-2090079 https://reactome.org/PathwayBrowser/#/R-MMU-2090079 GLB1 hydrolyses linker chain(2) IEA Mus musculus 15377 R-MMU-209055 https://reactome.org/PathwayBrowser/#/R-MMU-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Mus musculus 15377 R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 15377 R-MMU-209845 https://reactome.org/PathwayBrowser/#/R-MMU-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Mus musculus 15377 R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 15377 R-MMU-209891 https://reactome.org/PathwayBrowser/#/R-MMU-209891 Dopamine is oxidised to noradrenaline IEA Mus musculus 15377 R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 15377 R-MMU-2105001 https://reactome.org/PathwayBrowser/#/R-MMU-2105001 HEXA cleaves the terminal GalNAc from DS IEA Mus musculus 15377 R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus 15377 R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 15377 R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 15377 R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 15377 R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 15377 R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 15377 R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 15377 R-MMU-211923 https://reactome.org/PathwayBrowser/#/R-MMU-211923 CYP26C1 4-hydroxylates 9cRA IEA Mus musculus 15377 R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 15377 R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 15377 R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 15377 R-MMU-211950 https://reactome.org/PathwayBrowser/#/R-MMU-211950 CYP24A1 24-hydroxylates CTL IEA Mus musculus 15377 R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 15377 R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 15377 R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 15377 R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 15377 R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 15377 R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 15377 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 15377 R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 15377 R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 15377 R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 15377 R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 15377 R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 15377 R-MMU-2130725 https://reactome.org/PathwayBrowser/#/R-MMU-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Mus musculus 15377 R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 15377 R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 15377 R-MMU-2160492 https://reactome.org/PathwayBrowser/#/R-MMU-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Mus musculus 15377 R-MMU-2160874 https://reactome.org/PathwayBrowser/#/R-MMU-2160874 HYAL1 hydrolyses (HA)50 IEA Mus musculus 15377 R-MMU-2161187 https://reactome.org/PathwayBrowser/#/R-MMU-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Mus musculus 15377 R-MMU-2161195 https://reactome.org/PathwayBrowser/#/R-MMU-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Mus musculus 15377 R-MMU-2161526 https://reactome.org/PathwayBrowser/#/R-MMU-2161526 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 15377 R-MMU-2161533 https://reactome.org/PathwayBrowser/#/R-MMU-2161533 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 15377 R-MMU-2161646 https://reactome.org/PathwayBrowser/#/R-MMU-2161646 PGA2 is dehydrated to 15d-PGA2 TAS Mus musculus 15377 R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus 15377 R-MMU-2161791 https://reactome.org/PathwayBrowser/#/R-MMU-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Mus musculus 15377 R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus 15377 R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Mus musculus 15377 R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 15377 R-MMU-2161890 https://reactome.org/PathwayBrowser/#/R-MMU-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Mus musculus 15377 R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Mus musculus 15377 R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 15377 R-MMU-2161951 https://reactome.org/PathwayBrowser/#/R-MMU-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Mus musculus 15377 R-MMU-2161959 https://reactome.org/PathwayBrowser/#/R-MMU-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Mus musculus 15377 R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Mus musculus 15377 R-MMU-2161999 https://reactome.org/PathwayBrowser/#/R-MMU-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Mus musculus 15377 R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 15377 R-MMU-2162225 https://reactome.org/PathwayBrowser/#/R-MMU-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Mus musculus 15377 R-MMU-2162226 https://reactome.org/PathwayBrowser/#/R-MMU-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Mus musculus 15377 R-MMU-2162227 https://reactome.org/PathwayBrowser/#/R-MMU-2162227 GUSB tetramer hydrolyses (HA)2 IEA Mus musculus 15377 R-MMU-216723 https://reactome.org/PathwayBrowser/#/R-MMU-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Mus musculus 15377 R-MMU-216757 https://reactome.org/PathwayBrowser/#/R-MMU-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Mus musculus 15377 R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 15377 R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 15377 R-MMU-2187401 https://reactome.org/PathwayBrowser/#/R-MMU-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Mus musculus 15377 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 15377 R-MMU-2393939 https://reactome.org/PathwayBrowser/#/R-MMU-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 15377 R-MMU-2393954 https://reactome.org/PathwayBrowser/#/R-MMU-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 15377 R-MMU-2395340 https://reactome.org/PathwayBrowser/#/R-MMU-2395340 Formation of hydroxyallysine by LOX IEA Mus musculus 15377 R-MMU-2395818 https://reactome.org/PathwayBrowser/#/R-MMU-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Mus musculus 15377 R-MMU-2395849 https://reactome.org/PathwayBrowser/#/R-MMU-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 15377 R-MMU-2395869 https://reactome.org/PathwayBrowser/#/R-MMU-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 15377 R-MMU-2395872 https://reactome.org/PathwayBrowser/#/R-MMU-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Mus musculus 15377 R-MMU-2395873 https://reactome.org/PathwayBrowser/#/R-MMU-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Mus musculus 15377 R-MMU-2395876 https://reactome.org/PathwayBrowser/#/R-MMU-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 15377 R-MMU-2395879 https://reactome.org/PathwayBrowser/#/R-MMU-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 15377 R-MMU-2395965 https://reactome.org/PathwayBrowser/#/R-MMU-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Mus musculus 15377 R-MMU-2408528 https://reactome.org/PathwayBrowser/#/R-MMU-2408528 Excess SeMet is cleaved into MeSeH by PXLP-K211-Cth TAS Mus musculus 15377 R-MMU-2408551 https://reactome.org/PathwayBrowser/#/R-MMU-2408551 SeMet is converted to AdoSeMet by MAT IEA Mus musculus 15377 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 15377 R-MMU-2454118 https://reactome.org/PathwayBrowser/#/R-MMU-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Mus musculus 15377 R-MMU-2465924 https://reactome.org/PathwayBrowser/#/R-MMU-2465924 OPN1LW binds 11cRAL IEA Mus musculus 15377 R-MMU-2466085 https://reactome.org/PathwayBrowser/#/R-MMU-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Mus musculus 15377 R-MMU-2509793 https://reactome.org/PathwayBrowser/#/R-MMU-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Mus musculus 15377 R-MMU-2509816 https://reactome.org/PathwayBrowser/#/R-MMU-2509816 NUDT16 hydrolyses IDP to IMP IEA Mus musculus 15377 R-MMU-2509827 https://reactome.org/PathwayBrowser/#/R-MMU-2509827 ITPA hydrolyses ITP to IMP IEA Mus musculus 15377 R-MMU-2509831 https://reactome.org/PathwayBrowser/#/R-MMU-2509831 ITPA hydrolyses XTP to XMP IEA Mus musculus 15377 R-MMU-2509838 https://reactome.org/PathwayBrowser/#/R-MMU-2509838 ITPA hydrolyses dITP to dIMP IEA Mus musculus 15377 R-MMU-2529015 https://reactome.org/PathwayBrowser/#/R-MMU-2529015 Dephosphorylation of CK2-modified condensin I IEA Mus musculus 15377 R-MMU-2584246 https://reactome.org/PathwayBrowser/#/R-MMU-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Mus musculus 15377 R-MMU-2632521 https://reactome.org/PathwayBrowser/#/R-MMU-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Mus musculus 15377 R-MMU-265783 https://reactome.org/PathwayBrowser/#/R-MMU-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Mus musculus 15377 R-MMU-266012 https://reactome.org/PathwayBrowser/#/R-MMU-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Mus musculus 15377 R-MMU-266046 https://reactome.org/PathwayBrowser/#/R-MMU-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Mus musculus 15377 R-MMU-266051 https://reactome.org/PathwayBrowser/#/R-MMU-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Mus musculus 15377 R-MMU-266072 https://reactome.org/PathwayBrowser/#/R-MMU-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Mus musculus 15377 R-MMU-266082 https://reactome.org/PathwayBrowser/#/R-MMU-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Mus musculus 15377 R-MMU-2730847 https://reactome.org/PathwayBrowser/#/R-MMU-2730847 Hydrolysis of PIP2 by PLCG IEA Mus musculus 15377 R-MMU-2730849 https://reactome.org/PathwayBrowser/#/R-MMU-2730849 Calcineurin binds and dephosphorylates NFAT IEA Mus musculus 15377 R-MMU-2855047 https://reactome.org/PathwayBrowser/#/R-MMU-2855047 Hydrolysis of internal thioester in C4b IEA Mus musculus 15377 R-MMU-2995330 https://reactome.org/PathwayBrowser/#/R-MMU-2995330 COX10 transforms heme to heme O IEA Mus musculus 15377 R-MMU-2995334 https://reactome.org/PathwayBrowser/#/R-MMU-2995334 COX15 transforms heme O to heme A IEA Mus musculus 15377 R-MMU-2995388 https://reactome.org/PathwayBrowser/#/R-MMU-2995388 PP2A dephosphorylates BANF1 IEA Mus musculus 15377 R-MMU-3002811 https://reactome.org/PathwayBrowser/#/R-MMU-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Mus musculus 15377 R-MMU-3095901 https://reactome.org/PathwayBrowser/#/R-MMU-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Mus musculus 15377 R-MMU-3204311 https://reactome.org/PathwayBrowser/#/R-MMU-3204311 AOX1 oxidises PXL to PDXate IEA Mus musculus 15377 R-MMU-3215295 https://reactome.org/PathwayBrowser/#/R-MMU-3215295 USP7 deubiquitinates MDM2 IEA Mus musculus 15377 R-MMU-3215310 https://reactome.org/PathwayBrowser/#/R-MMU-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Mus musculus 15377 R-MMU-3247569 https://reactome.org/PathwayBrowser/#/R-MMU-3247569 PADI4 deiminates Histones IEA Mus musculus 15377 R-MMU-3262512 https://reactome.org/PathwayBrowser/#/R-MMU-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Mus musculus 15377 R-MMU-3266566 https://reactome.org/PathwayBrowser/#/R-MMU-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Mus musculus 15377 R-MMU-3322995 https://reactome.org/PathwayBrowser/#/R-MMU-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Mus musculus 15377 R-MMU-3323013 https://reactome.org/PathwayBrowser/#/R-MMU-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 15377 R-MMU-3341277 https://reactome.org/PathwayBrowser/#/R-MMU-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 15377 R-MMU-3341296 https://reactome.org/PathwayBrowser/#/R-MMU-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Mus musculus 15377 R-MMU-3341343 https://reactome.org/PathwayBrowser/#/R-MMU-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Mus musculus 15377 R-MMU-3341397 https://reactome.org/PathwayBrowser/#/R-MMU-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 15377 R-MMU-3343700 https://reactome.org/PathwayBrowser/#/R-MMU-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 15377 R-MMU-3371467 https://reactome.org/PathwayBrowser/#/R-MMU-3371467 SIRT1 deacetylates HSF1 IEA Mus musculus 15377 R-MMU-3446785 https://reactome.org/PathwayBrowser/#/R-MMU-3446785 Ptpmt1 dephosphorylates PGP to PG TAS Mus musculus 15377 R-MMU-350604 https://reactome.org/PathwayBrowser/#/R-MMU-350604 Agmatine + H2O <=> putrescine + urea IEA Mus musculus 15377 R-MMU-350901 https://reactome.org/PathwayBrowser/#/R-MMU-350901 Iodide is organified IEA Mus musculus 15377 R-MMU-3640872 https://reactome.org/PathwayBrowser/#/R-MMU-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Mus musculus 15377 R-MMU-3697882 https://reactome.org/PathwayBrowser/#/R-MMU-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Mus musculus 15377 R-MMU-3697894 https://reactome.org/PathwayBrowser/#/R-MMU-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Mus musculus 15377 R-MMU-3697899 https://reactome.org/PathwayBrowser/#/R-MMU-3697899 Atp7a transfers Cu from Atox1 to Sod3 TAS Mus musculus 15377 R-MMU-374909 https://reactome.org/PathwayBrowser/#/R-MMU-374909 Catabolism of Noradrenaline IEA Mus musculus 15377 R-MMU-3769447 https://reactome.org/PathwayBrowser/#/R-MMU-3769447 HDAC1:2-containing complex deacetylate histones IEA Mus musculus 15377 R-MMU-377643 https://reactome.org/PathwayBrowser/#/R-MMU-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Mus musculus 15377 R-MMU-3777129 https://reactome.org/PathwayBrowser/#/R-MMU-3777129 HDAC3 containing complexes deacetylate histone IEA Mus musculus 15377 R-MMU-3781018 https://reactome.org/PathwayBrowser/#/R-MMU-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Mus musculus 15377 R-MMU-3782637 https://reactome.org/PathwayBrowser/#/R-MMU-3782637 HDAC8 deacetylates histones IEA Mus musculus 15377 R-MMU-3782655 https://reactome.org/PathwayBrowser/#/R-MMU-3782655 HDAC10 deacetylates histone IEA Mus musculus 15377 R-MMU-379382 https://reactome.org/PathwayBrowser/#/R-MMU-379382 MAOA:FAD deaminates DA to DOPAC IEA Mus musculus 15377 R-MMU-379395 https://reactome.org/PathwayBrowser/#/R-MMU-379395 MAOA:FAD deaminates 3MT to HVA IEA Mus musculus 15377 R-MMU-380949 https://reactome.org/PathwayBrowser/#/R-MMU-380949 AMPK is dephosphorylated IEA Mus musculus 15377 R-MMU-382553 https://reactome.org/PathwayBrowser/#/R-MMU-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Mus musculus 15377 R-MMU-382560 https://reactome.org/PathwayBrowser/#/R-MMU-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Mus musculus 15377 R-MMU-382575 https://reactome.org/PathwayBrowser/#/R-MMU-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Mus musculus 15377 R-MMU-383190 https://reactome.org/PathwayBrowser/#/R-MMU-383190 HCO3- transport through ion channel IEA Mus musculus 15377 R-MMU-389821 https://reactome.org/PathwayBrowser/#/R-MMU-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Mus musculus 15377 R-MMU-389862 https://reactome.org/PathwayBrowser/#/R-MMU-389862 Conversion of glyoxylate to oxalate IEA Mus musculus 15377 R-MMU-389986 https://reactome.org/PathwayBrowser/#/R-MMU-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Mus musculus 15377 R-MMU-390252 https://reactome.org/PathwayBrowser/#/R-MMU-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Mus musculus 15377 R-MMU-390304 https://reactome.org/PathwayBrowser/#/R-MMU-390304 acetyl-CoA + H2O => acetate + CoASH IEA Mus musculus 15377 R-MMU-390329 https://reactome.org/PathwayBrowser/#/R-MMU-390329 Dephosphorylation of AKT by PP2A IEA Mus musculus 15377 R-MMU-399998 https://reactome.org/PathwayBrowser/#/R-MMU-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Mus musculus 15377 R-MMU-4084976 https://reactome.org/PathwayBrowser/#/R-MMU-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Mus musculus 15377 R-MMU-4084989 https://reactome.org/PathwayBrowser/#/R-MMU-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Mus musculus 15377 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 15377 R-MMU-4084999 https://reactome.org/PathwayBrowser/#/R-MMU-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 15377 R-MMU-4085021 https://reactome.org/PathwayBrowser/#/R-MMU-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Mus musculus 15377 R-MMU-4085029 https://reactome.org/PathwayBrowser/#/R-MMU-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 15377 R-MMU-4086392 https://reactome.org/PathwayBrowser/#/R-MMU-4086392 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 15377 R-MMU-4088141 https://reactome.org/PathwayBrowser/#/R-MMU-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Mus musculus 15377 R-MMU-4093339 https://reactome.org/PathwayBrowser/#/R-MMU-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Mus musculus 15377 R-MMU-416559 https://reactome.org/PathwayBrowser/#/R-MMU-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Mus musculus 15377 R-MMU-418553 https://reactome.org/PathwayBrowser/#/R-MMU-418553 cAMP degradation by Phosphodiesterases IEA Mus musculus 15377 R-MMU-426043 https://reactome.org/PathwayBrowser/#/R-MMU-426043 2-AG hydrolysis to arachidonate by MAGL IEA Mus musculus 15377 R-MMU-428205 https://reactome.org/PathwayBrowser/#/R-MMU-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Mus musculus 15377 R-MMU-428231 https://reactome.org/PathwayBrowser/#/R-MMU-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Mus musculus 15377 R-MMU-428259 https://reactome.org/PathwayBrowser/#/R-MMU-428259 DEGS1 dehydrogenates dihydroceramide IEA Mus musculus 15377 R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 15377 R-MMU-428262 https://reactome.org/PathwayBrowser/#/R-MMU-428262 ACER3 hydrolyzes phytoceramide IEA Mus musculus 15377 R-MMU-428664 https://reactome.org/PathwayBrowser/#/R-MMU-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Mus musculus 15377 R-MMU-428690 https://reactome.org/PathwayBrowser/#/R-MMU-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Mus musculus 15377 R-MMU-428696 https://reactome.org/PathwayBrowser/#/R-MMU-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Mus musculus 15377 R-MMU-429157 https://reactome.org/PathwayBrowser/#/R-MMU-429157 ABCC4 accumulation of dense granule contents IEA Mus musculus 15377 R-MMU-429860 https://reactome.org/PathwayBrowser/#/R-MMU-429860 DCP1-DCP2 complex decaps mRNA IEA Mus musculus 15377 R-MMU-429955 https://reactome.org/PathwayBrowser/#/R-MMU-429955 CCR4-NOT complex deadenylates mRNA IEA Mus musculus 15377 R-MMU-429961 https://reactome.org/PathwayBrowser/#/R-MMU-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Mus musculus 15377 R-MMU-429992 https://reactome.org/PathwayBrowser/#/R-MMU-429992 PARN deadenylates mRNA IEA Mus musculus 15377 R-MMU-430021 https://reactome.org/PathwayBrowser/#/R-MMU-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Mus musculus 15377 R-MMU-430028 https://reactome.org/PathwayBrowser/#/R-MMU-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Mus musculus 15377 R-MMU-432010 https://reactome.org/PathwayBrowser/#/R-MMU-432010 Aquaporin-1 passively transports water into cell IEA Mus musculus 15377 R-MMU-432054 https://reactome.org/PathwayBrowser/#/R-MMU-432054 Aquaporin-1 passively transports water out of cell IEA Mus musculus 15377 R-MMU-432065 https://reactome.org/PathwayBrowser/#/R-MMU-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Mus musculus 15377 R-MMU-432067 https://reactome.org/PathwayBrowser/#/R-MMU-432067 Aquaporin-4 passively transports water out of cell IEA Mus musculus 15377 R-MMU-4419948 https://reactome.org/PathwayBrowser/#/R-MMU-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Mus musculus 15377 R-MMU-445714 https://reactome.org/PathwayBrowser/#/R-MMU-445714 Aquaporin-3 passively transports water out of cell IEA Mus musculus 15377 R-MMU-446200 https://reactome.org/PathwayBrowser/#/R-MMU-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Mus musculus 15377 R-MMU-449937 https://reactome.org/PathwayBrowser/#/R-MMU-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Mus musculus 15377 R-MMU-452036 https://reactome.org/PathwayBrowser/#/R-MMU-452036 arginine + H2O => ornithine + urea [ARG2] IEA Mus musculus 15377 R-MMU-4551451 https://reactome.org/PathwayBrowser/#/R-MMU-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Mus musculus 15377 R-MMU-4641236 https://reactome.org/PathwayBrowser/#/R-MMU-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Mus musculus 15377 R-MMU-504054 https://reactome.org/PathwayBrowser/#/R-MMU-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Mus musculus 15377 R-MMU-507868 https://reactome.org/PathwayBrowser/#/R-MMU-507868 Aquaporins passively transport water into cells IEA Mus musculus 15377 R-MMU-507870 https://reactome.org/PathwayBrowser/#/R-MMU-507870 Aquaporins passively transport water out of cells IEA Mus musculus 15377 R-MMU-508308 https://reactome.org/PathwayBrowser/#/R-MMU-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Mus musculus 15377 R-MMU-5221130 https://reactome.org/PathwayBrowser/#/R-MMU-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Mus musculus 15377 R-MMU-5223313 https://reactome.org/PathwayBrowser/#/R-MMU-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Mus musculus 15377 R-MMU-5223317 https://reactome.org/PathwayBrowser/#/R-MMU-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Mus musculus 15377 R-MMU-5251955 https://reactome.org/PathwayBrowser/#/R-MMU-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Mus musculus 15377 R-MMU-5251959 https://reactome.org/PathwayBrowser/#/R-MMU-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Mus musculus 15377 R-MMU-5251989 https://reactome.org/PathwayBrowser/#/R-MMU-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Mus musculus 15377 R-MMU-5263614 https://reactome.org/PathwayBrowser/#/R-MMU-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Mus musculus 15377 R-MMU-5263616 https://reactome.org/PathwayBrowser/#/R-MMU-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Mus musculus 15377 R-MMU-5362459 https://reactome.org/PathwayBrowser/#/R-MMU-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Mus musculus 15377 R-MMU-5362522 https://reactome.org/PathwayBrowser/#/R-MMU-5362522 ALDHs oxidise atRAL to atRA IEA Mus musculus 15377 R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 15377 R-MMU-5423647 https://reactome.org/PathwayBrowser/#/R-MMU-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Mus musculus 15377 R-MMU-5423664 https://reactome.org/PathwayBrowser/#/R-MMU-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Mus musculus 15377 R-MMU-5423672 https://reactome.org/PathwayBrowser/#/R-MMU-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Mus musculus 15377 R-MMU-5423678 https://reactome.org/PathwayBrowser/#/R-MMU-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Mus musculus 15377 R-MMU-5433072 https://reactome.org/PathwayBrowser/#/R-MMU-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Mus musculus 15377 R-MMU-5433074 https://reactome.org/PathwayBrowser/#/R-MMU-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 15377 R-MMU-548843 https://reactome.org/PathwayBrowser/#/R-MMU-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Mus musculus 15377 R-MMU-5602295 https://reactome.org/PathwayBrowser/#/R-MMU-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Mus musculus 15377 R-MMU-5603114 https://reactome.org/PathwayBrowser/#/R-MMU-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Mus musculus 15377 R-MMU-5607735 https://reactome.org/PathwayBrowser/#/R-MMU-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Mus musculus 15377 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 15377 R-MMU-5623513 https://reactome.org/PathwayBrowser/#/R-MMU-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Mus musculus 15377 R-MMU-5628905 https://reactome.org/PathwayBrowser/#/R-MMU-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Mus musculus 15377 R-MMU-5631885 https://reactome.org/PathwayBrowser/#/R-MMU-5631885 PRDX1 overoxidizes IEA Mus musculus 15377 R-MMU-5649705 https://reactome.org/PathwayBrowser/#/R-MMU-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Mus musculus 15377 R-MMU-5651828 https://reactome.org/PathwayBrowser/#/R-MMU-5651828 PARG dePARylates PARP1,PARP2 IEA Mus musculus 15377 R-MMU-5653770 https://reactome.org/PathwayBrowser/#/R-MMU-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Mus musculus 15377 R-MMU-5653786 https://reactome.org/PathwayBrowser/#/R-MMU-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Mus musculus 15377 R-MMU-5659861 https://reactome.org/PathwayBrowser/#/R-MMU-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Mus musculus 15377 R-MMU-5662692 https://reactome.org/PathwayBrowser/#/R-MMU-5662692 Dopa is oxidized to dopaquinone by TYR IEA Mus musculus 15377 R-MMU-5665809 https://reactome.org/PathwayBrowser/#/R-MMU-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Mus musculus 15377 R-MMU-5672957 https://reactome.org/PathwayBrowser/#/R-MMU-5672957 PP2A dephosphorylates KSR1 IEA Mus musculus 15377 R-MMU-5672961 https://reactome.org/PathwayBrowser/#/R-MMU-5672961 PP2A dephosphorylates inactive RAFs IEA Mus musculus 15377 R-MMU-5675373 https://reactome.org/PathwayBrowser/#/R-MMU-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Mus musculus 15377 R-MMU-5675376 https://reactome.org/PathwayBrowser/#/R-MMU-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Mus musculus 15377 R-MMU-5675431 https://reactome.org/PathwayBrowser/#/R-MMU-5675431 PP2A dephosphorylates RAF1 IEA Mus musculus 15377 R-MMU-5675433 https://reactome.org/PathwayBrowser/#/R-MMU-5675433 PP5 dephosphorylates RAF1 S338 IEA Mus musculus 15377 R-MMU-5676637 https://reactome.org/PathwayBrowser/#/R-MMU-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Mus musculus 15377 R-MMU-5678327 https://reactome.org/PathwayBrowser/#/R-MMU-5678327 MIOX oxidises Ins to GlcA IEA Mus musculus 15377 R-MMU-5678706 https://reactome.org/PathwayBrowser/#/R-MMU-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Mus musculus 15377 R-MMU-5678863 https://reactome.org/PathwayBrowser/#/R-MMU-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Mus musculus 15377 R-MMU-5679041 https://reactome.org/PathwayBrowser/#/R-MMU-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 15377 R-MMU-5682285 https://reactome.org/PathwayBrowser/#/R-MMU-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Mus musculus 15377 R-MMU-5683405 https://reactome.org/PathwayBrowser/#/R-MMU-5683405 PPP5C dephosphorylates TP53BP1 IEA Mus musculus 15377 R-MMU-5683714 https://reactome.org/PathwayBrowser/#/R-MMU-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Mus musculus 15377 R-MMU-5683967 https://reactome.org/PathwayBrowser/#/R-MMU-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Mus musculus 15377 R-MMU-5684864 https://reactome.org/PathwayBrowser/#/R-MMU-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Mus musculus 15377 R-MMU-5685902 https://reactome.org/PathwayBrowser/#/R-MMU-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Mus musculus 15377 R-MMU-5685994 https://reactome.org/PathwayBrowser/#/R-MMU-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Mus musculus 15377 R-MMU-5687464 https://reactome.org/PathwayBrowser/#/R-MMU-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Mus musculus 15377 R-MMU-5687664 https://reactome.org/PathwayBrowser/#/R-MMU-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Mus musculus 15377 R-MMU-5687758 https://reactome.org/PathwayBrowser/#/R-MMU-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Mus musculus 15377 R-MMU-5688797 https://reactome.org/PathwayBrowser/#/R-MMU-5688797 ATXN3 family cleave Ub chains IEA Mus musculus 15377 R-MMU-5688837 https://reactome.org/PathwayBrowser/#/R-MMU-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Mus musculus 15377 R-MMU-5689000 https://reactome.org/PathwayBrowser/#/R-MMU-5689000 AADAC deacetylates PHEN IEA Mus musculus 15377 R-MMU-5689950 https://reactome.org/PathwayBrowser/#/R-MMU-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Mus musculus 15377 R-MMU-5689972 https://reactome.org/PathwayBrowser/#/R-MMU-5689972 USP2 deubiquitinates MDM2,MDM4 IEA Mus musculus 15377 R-MMU-5689973 https://reactome.org/PathwayBrowser/#/R-MMU-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Mus musculus 15377 R-MMU-5690042 https://reactome.org/PathwayBrowser/#/R-MMU-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 15377 R-MMU-5690043 https://reactome.org/PathwayBrowser/#/R-MMU-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 15377 R-MMU-5690046 https://reactome.org/PathwayBrowser/#/R-MMU-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Mus musculus 15377 R-MMU-5690066 https://reactome.org/PathwayBrowser/#/R-MMU-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 15377 R-MMU-5690080 https://reactome.org/PathwayBrowser/#/R-MMU-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Mus musculus 15377 R-MMU-5690152 https://reactome.org/PathwayBrowser/#/R-MMU-5690152 USP5 cleaves polyubiquitin IEA Mus musculus 15377 R-MMU-5690157 https://reactome.org/PathwayBrowser/#/R-MMU-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Mus musculus 15377 R-MMU-5690159 https://reactome.org/PathwayBrowser/#/R-MMU-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Mus musculus 15377 R-MMU-5690196 https://reactome.org/PathwayBrowser/#/R-MMU-5690196 USP8 deubiquitinates RNF128 IEA Mus musculus 15377 R-MMU-5690319 https://reactome.org/PathwayBrowser/#/R-MMU-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Mus musculus 15377 R-MMU-5690517 https://reactome.org/PathwayBrowser/#/R-MMU-5690517 PPT1 hydrolyses palmitoylated proteins IEA Mus musculus 15377 R-MMU-5690565 https://reactome.org/PathwayBrowser/#/R-MMU-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Mus musculus 15377 R-MMU-5690759 https://reactome.org/PathwayBrowser/#/R-MMU-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Mus musculus 15377 R-MMU-5690790 https://reactome.org/PathwayBrowser/#/R-MMU-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Mus musculus 15377 R-MMU-5690808 https://reactome.org/PathwayBrowser/#/R-MMU-5690808 UCHL3, SENP8 cleave NEDD8 IEA Mus musculus 15377 R-MMU-5690856 https://reactome.org/PathwayBrowser/#/R-MMU-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Mus musculus 15377 R-MMU-5690870 https://reactome.org/PathwayBrowser/#/R-MMU-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Mus musculus 15377 R-MMU-5691381 https://reactome.org/PathwayBrowser/#/R-MMU-5691381 MYSM1 deubiquitinates Histone H2A IEA Mus musculus 15377 R-MMU-5691411 https://reactome.org/PathwayBrowser/#/R-MMU-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Mus musculus 15377 R-MMU-5691439 https://reactome.org/PathwayBrowser/#/R-MMU-5691439 BRISC complex deubiquitinates NLRP3 IEA Mus musculus 15377 R-MMU-5691507 https://reactome.org/PathwayBrowser/#/R-MMU-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Mus musculus 15377 R-MMU-5691512 https://reactome.org/PathwayBrowser/#/R-MMU-5691512 APEH hydrolyses NAc-Ser-protein IEA Mus musculus 15377 R-MMU-5692261 https://reactome.org/PathwayBrowser/#/R-MMU-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Mus musculus 15377 R-MMU-5692283 https://reactome.org/PathwayBrowser/#/R-MMU-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Mus musculus 15377 R-MMU-5692462 https://reactome.org/PathwayBrowser/#/R-MMU-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Mus musculus 15377 R-MMU-5692480 https://reactome.org/PathwayBrowser/#/R-MMU-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Mus musculus 15377 R-MMU-5692754 https://reactome.org/PathwayBrowser/#/R-MMU-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Mus musculus 15377 R-MMU-5693153 https://reactome.org/PathwayBrowser/#/R-MMU-5693153 PPM1K dephosphorylates p-BCKDH IEA Mus musculus 15377 R-MMU-5693373 https://reactome.org/PathwayBrowser/#/R-MMU-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Mus musculus 15377 R-MMU-5693608 https://reactome.org/PathwayBrowser/#/R-MMU-5693608 Initial resection of double-strand break ends IEA Mus musculus 15377 R-MMU-5693691 https://reactome.org/PathwayBrowser/#/R-MMU-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Mus musculus 15377 R-MMU-5693724 https://reactome.org/PathwayBrowser/#/R-MMU-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Mus musculus 15377 R-MMU-5693742 https://reactome.org/PathwayBrowser/#/R-MMU-5693742 FAAH hydrolyses AEA to AA and ETA IEA Mus musculus 15377 R-MMU-5693761 https://reactome.org/PathwayBrowser/#/R-MMU-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Mus musculus 15377 R-MMU-5693807 https://reactome.org/PathwayBrowser/#/R-MMU-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Mus musculus 15377 R-MMU-5694077 https://reactome.org/PathwayBrowser/#/R-MMU-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Mus musculus 15377 R-MMU-5694109 https://reactome.org/PathwayBrowser/#/R-MMU-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Mus musculus 15377 R-MMU-5694126 https://reactome.org/PathwayBrowser/#/R-MMU-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Mus musculus 15377 R-MMU-5694137 https://reactome.org/PathwayBrowser/#/R-MMU-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Mus musculus 15377 R-MMU-5694421 https://reactome.org/PathwayBrowser/#/R-MMU-5694421 PP6 dephosphorylates SEC24 IEA Mus musculus 15377 R-MMU-5694462 https://reactome.org/PathwayBrowser/#/R-MMU-5694462 ABHD6,12 hydrolyse 3AG IEA Mus musculus 15377 R-MMU-5694485 https://reactome.org/PathwayBrowser/#/R-MMU-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Mus musculus 15377 R-MMU-5694563 https://reactome.org/PathwayBrowser/#/R-MMU-5694563 ABHD10 hydrolyses MPAG IEA Mus musculus 15377 R-MMU-5694583 https://reactome.org/PathwayBrowser/#/R-MMU-5694583 ABHD4 hydrolyses NAPE IEA Mus musculus 15377 R-MMU-5695964 https://reactome.org/PathwayBrowser/#/R-MMU-5695964 ABHD14B hydrolyses PNPB IEA Mus musculus 15377 R-MMU-5696049 https://reactome.org/PathwayBrowser/#/R-MMU-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 15377 R-MMU-5696080 https://reactome.org/PathwayBrowser/#/R-MMU-5696080 ALDH3B1 oxidises HXAL to PALM IEA Mus musculus 15377 R-MMU-5696091 https://reactome.org/PathwayBrowser/#/R-MMU-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Mus musculus 15377 R-MMU-5696101 https://reactome.org/PathwayBrowser/#/R-MMU-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Mus musculus 15377 R-MMU-5696119 https://reactome.org/PathwayBrowser/#/R-MMU-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Mus musculus 15377 R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 15377 R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 15377 R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 15377 R-MMU-5696197 https://reactome.org/PathwayBrowser/#/R-MMU-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Mus musculus 15377 R-MMU-5696230 https://reactome.org/PathwayBrowser/#/R-MMU-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Mus musculus 15377 R-MMU-5696365 https://reactome.org/PathwayBrowser/#/R-MMU-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Mus musculus 15377 R-MMU-5696408 https://reactome.org/PathwayBrowser/#/R-MMU-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Mus musculus 15377 R-MMU-5696415 https://reactome.org/PathwayBrowser/#/R-MMU-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Mus musculus 15377 R-MMU-5696465 https://reactome.org/PathwayBrowser/#/R-MMU-5696465 USP45 deubiquitinates ERCC1 IEA Mus musculus 15377 R-MMU-5696534 https://reactome.org/PathwayBrowser/#/R-MMU-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Mus musculus 15377 R-MMU-5696564 https://reactome.org/PathwayBrowser/#/R-MMU-5696564 USP25 deubiquitinates DDX58 IEA Mus musculus 15377 R-MMU-5696600 https://reactome.org/PathwayBrowser/#/R-MMU-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Mus musculus 15377 R-MMU-5696605 https://reactome.org/PathwayBrowser/#/R-MMU-5696605 USP12, USP26 deubiquitinate AR IEA Mus musculus 15377 R-MMU-5696627 https://reactome.org/PathwayBrowser/#/R-MMU-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Mus musculus 15377 R-MMU-5696872 https://reactome.org/PathwayBrowser/#/R-MMU-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Mus musculus 15377 R-MMU-5696914 https://reactome.org/PathwayBrowser/#/R-MMU-5696914 USP28 deubiquitinates CLSPN and MYC IEA Mus musculus 15377 R-MMU-5696945 https://reactome.org/PathwayBrowser/#/R-MMU-5696945 USP33 deubiquitinates CCP110,ARRB IEA Mus musculus 15377 R-MMU-5696947 https://reactome.org/PathwayBrowser/#/R-MMU-5696947 USP47 deubiquitinates POLB IEA Mus musculus 15377 R-MMU-5696958 https://reactome.org/PathwayBrowser/#/R-MMU-5696958 USP44 deubiquitinates CDC20 IEA Mus musculus 15377 R-MMU-5696968 https://reactome.org/PathwayBrowser/#/R-MMU-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Mus musculus 15377 R-MMU-5696997 https://reactome.org/PathwayBrowser/#/R-MMU-5696997 USP24 deubiquitinates DDB2 IEA Mus musculus 15377 R-MMU-5697009 https://reactome.org/PathwayBrowser/#/R-MMU-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Mus musculus 15377 R-MMU-6781764 https://reactome.org/PathwayBrowser/#/R-MMU-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Mus musculus 15377 R-MMU-6781779 https://reactome.org/PathwayBrowser/#/R-MMU-6781779 USP13 deubiquitinates BECN1,USP10 IEA Mus musculus 15377 R-MMU-6781814 https://reactome.org/PathwayBrowser/#/R-MMU-6781814 USP19 deubiquitinates RNF123 IEA Mus musculus 15377 R-MMU-6781897 https://reactome.org/PathwayBrowser/#/R-MMU-6781897 USP11 deubiquitinates NFKBIA IEA Mus musculus 15377 R-MMU-6782069 https://reactome.org/PathwayBrowser/#/R-MMU-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Mus musculus 15377 R-MMU-6782106 https://reactome.org/PathwayBrowser/#/R-MMU-6782106 USP10 deubiquitinates SNX3, CFTR IEA Mus musculus 15377 R-MMU-6782628 https://reactome.org/PathwayBrowser/#/R-MMU-6782628 USP8 deubiquitinates STAM2:HGS IEA Mus musculus 15377 R-MMU-6782820 https://reactome.org/PathwayBrowser/#/R-MMU-6782820 USP17 deubiquitinates SUDS3 IEA Mus musculus 15377 R-MMU-6783177 https://reactome.org/PathwayBrowser/#/R-MMU-6783177 USP21 deubiquitinates GATA3,IL33 IEA Mus musculus 15377 R-MMU-6783221 https://reactome.org/PathwayBrowser/#/R-MMU-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Mus musculus 15377 R-MMU-6784959 https://reactome.org/PathwayBrowser/#/R-MMU-6784959 BPHL hydrolyses VACV to ACV IEA Mus musculus 15377 R-MMU-6786190 https://reactome.org/PathwayBrowser/#/R-MMU-6786190 CMBL hydrolyses OM to OLMS IEA Mus musculus 15377 R-MMU-6786239 https://reactome.org/PathwayBrowser/#/R-MMU-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Mus musculus 15377 R-MMU-6786295 https://reactome.org/PathwayBrowser/#/R-MMU-6786295 Dctpp1 hydrolyses 5idCTP TAS Mus musculus 15377 R-MMU-6786421 https://reactome.org/PathwayBrowser/#/R-MMU-6786421 CHIA hydrolyses chitin IEA Mus musculus 15377 R-MMU-6786650 https://reactome.org/PathwayBrowser/#/R-MMU-6786650 DDHD1,2 hydrolyse PA IEA Mus musculus 15377 R-MMU-6786652 https://reactome.org/PathwayBrowser/#/R-MMU-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Mus musculus 15377 R-MMU-6787632 https://reactome.org/PathwayBrowser/#/R-MMU-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Mus musculus 15377 R-MMU-6788295 https://reactome.org/PathwayBrowser/#/R-MMU-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Mus musculus 15377 R-MMU-6788912 https://reactome.org/PathwayBrowser/#/R-MMU-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Mus musculus 15377 R-MMU-6789031 https://reactome.org/PathwayBrowser/#/R-MMU-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 15377 R-MMU-6789126 https://reactome.org/PathwayBrowser/#/R-MMU-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 15377 R-MMU-6789310 https://reactome.org/PathwayBrowser/#/R-MMU-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Mus musculus 15377 R-MMU-6792445 https://reactome.org/PathwayBrowser/#/R-MMU-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Mus musculus 15377 R-MMU-6792863 https://reactome.org/PathwayBrowser/#/R-MMU-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Mus musculus 15377 R-MMU-6797627 https://reactome.org/PathwayBrowser/#/R-MMU-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Mus musculus 15377 R-MMU-6797630 https://reactome.org/PathwayBrowser/#/R-MMU-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Mus musculus 15377 R-MMU-6797653 https://reactome.org/PathwayBrowser/#/R-MMU-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Mus musculus 15377 R-MMU-6797913 https://reactome.org/PathwayBrowser/#/R-MMU-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Mus musculus 15377 R-MMU-6797955 https://reactome.org/PathwayBrowser/#/R-MMU-6797955 ALDH7A1 oxidises BETALD to BET IEA Mus musculus 15377 R-MMU-6799545 https://reactome.org/PathwayBrowser/#/R-MMU-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Mus musculus 15377 R-MMU-6799581 https://reactome.org/PathwayBrowser/#/R-MMU-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Mus musculus 15377 R-MMU-6799604 https://reactome.org/PathwayBrowser/#/R-MMU-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Mus musculus 15377 R-MMU-6799695 https://reactome.org/PathwayBrowser/#/R-MMU-6799695 GPX5,6 reduce H2O2 to H2O IEA Mus musculus 15377 R-MMU-6799977 https://reactome.org/PathwayBrowser/#/R-MMU-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Mus musculus 15377 R-MMU-6800198 https://reactome.org/PathwayBrowser/#/R-MMU-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Mus musculus 15377 R-MMU-6800200 https://reactome.org/PathwayBrowser/#/R-MMU-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Mus musculus 15377 R-MMU-6800299 https://reactome.org/PathwayBrowser/#/R-MMU-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Mus musculus 15377 R-MMU-6801462 https://reactome.org/PathwayBrowser/#/R-MMU-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Mus musculus 15377 R-MMU-6803545 https://reactome.org/PathwayBrowser/#/R-MMU-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Mus musculus 15377 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 15377 R-MMU-6803789 https://reactome.org/PathwayBrowser/#/R-MMU-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Mus musculus 15377 R-MMU-6805650 https://reactome.org/PathwayBrowser/#/R-MMU-6805650 MTA2-NuRD complex deacetylates TP53 IEA Mus musculus 15377 R-MMU-6807008 https://reactome.org/PathwayBrowser/#/R-MMU-6807008 PTPRJ dephosphorylates MET IEA Mus musculus 15377 R-MMU-6807027 https://reactome.org/PathwayBrowser/#/R-MMU-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Mus musculus 15377 R-MMU-6807053 https://reactome.org/PathwayBrowser/#/R-MMU-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Mus musculus 15377 R-MMU-6807118 https://reactome.org/PathwayBrowser/#/R-MMU-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Mus musculus 15377 R-MMU-6807206 https://reactome.org/PathwayBrowser/#/R-MMU-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Mus musculus 15377 R-MMU-6807214 https://reactome.org/PathwayBrowser/#/R-MMU-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Mus musculus 15377 R-MMU-6808464 https://reactome.org/PathwayBrowser/#/R-MMU-6808464 ALDH3B2 oxidises HXAL to PALM IEA Mus musculus 15377 R-MMU-6808487 https://reactome.org/PathwayBrowser/#/R-MMU-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 15377 R-MMU-6808496 https://reactome.org/PathwayBrowser/#/R-MMU-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 15377 R-MMU-6809263 https://reactome.org/PathwayBrowser/#/R-MMU-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Mus musculus 15377 R-MMU-6809287 https://reactome.org/PathwayBrowser/#/R-MMU-6809287 NUDT12 hydrolyses NADH to NMNH IEA Mus musculus 15377 R-MMU-6809320 https://reactome.org/PathwayBrowser/#/R-MMU-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Mus musculus 15377 R-MMU-6809325 https://reactome.org/PathwayBrowser/#/R-MMU-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Mus musculus 15377 R-MMU-6809624 https://reactome.org/PathwayBrowser/#/R-MMU-6809624 I(1,3)P2 is dephosphorylated into I1P by Mtmr7 TAS Mus musculus 15377 R-MMU-6809627 https://reactome.org/PathwayBrowser/#/R-MMU-6809627 I(1,3)P2 is dephosphorylated into I1P by Mtmr7:Mtmr9 TAS Mus musculus 15377 R-MMU-6809720 https://reactome.org/PathwayBrowser/#/R-MMU-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Mus musculus 15377 R-MMU-6809777 https://reactome.org/PathwayBrowser/#/R-MMU-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Mus musculus 15377 R-MMU-6809778 https://reactome.org/PathwayBrowser/#/R-MMU-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Mus musculus 15377 R-MMU-6809945 https://reactome.org/PathwayBrowser/#/R-MMU-6809945 PI(3,5)P2 is dephosphorylated to PI5P by the Mtmr2:Sbf2 tetramer at the plasma membrane TAS Mus musculus 15377 R-MMU-6809977 https://reactome.org/PathwayBrowser/#/R-MMU-6809977 PI3P is dephosphorylated to PI by the Mtmr2:Sbf2 tetramer at the plasma membrane TAS Mus musculus 15377 R-MMU-6810076 https://reactome.org/PathwayBrowser/#/R-MMU-6810076 DDO oxidizes D-Asp to OA IEA Mus musculus 15377 R-MMU-6810410 https://reactome.org/PathwayBrowser/#/R-MMU-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Mus musculus 15377 R-MMU-6810452 https://reactome.org/PathwayBrowser/#/R-MMU-6810452 Nudt7 hydrolyses CoA-SH to 3',5'-ADP and PPANT TAS Mus musculus 15377 R-MMU-6810464 https://reactome.org/PathwayBrowser/#/R-MMU-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Mus musculus 15377 R-MMU-6810472 https://reactome.org/PathwayBrowser/#/R-MMU-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Mus musculus 15377 R-MMU-6810474 https://reactome.org/PathwayBrowser/#/R-MMU-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Mus musculus 15377 R-MMU-6811504 https://reactome.org/PathwayBrowser/#/R-MMU-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Mus musculus 15377 R-MMU-6813720 https://reactome.org/PathwayBrowser/#/R-MMU-6813720 NCEH1 hydrolyzes cholesterol esters IEA Mus musculus 15377 R-MMU-6813740 https://reactome.org/PathwayBrowser/#/R-MMU-6813740 GDE1 hydrolyzes GroPIns IEA Mus musculus 15377 R-MMU-6813749 https://reactome.org/PathwayBrowser/#/R-MMU-6813749 ALDH1A1 oxidises GA to DGA IEA Mus musculus 15377 R-MMU-6814137 https://reactome.org/PathwayBrowser/#/R-MMU-6814137 Gdpd5 hydrolyzes GPCho TAS Mus musculus 15377 R-MMU-6814254 https://reactome.org/PathwayBrowser/#/R-MMU-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Mus musculus 15377 R-MMU-6814797 https://reactome.org/PathwayBrowser/#/R-MMU-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Mus musculus 15377 R-MMU-69199 https://reactome.org/PathwayBrowser/#/R-MMU-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Mus musculus 15377 R-MMU-70262 https://reactome.org/PathwayBrowser/#/R-MMU-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Mus musculus 15377 R-MMU-70479 https://reactome.org/PathwayBrowser/#/R-MMU-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Mus musculus 15377 R-MMU-70494 https://reactome.org/PathwayBrowser/#/R-MMU-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Mus musculus 15377 R-MMU-70569 https://reactome.org/PathwayBrowser/#/R-MMU-70569 arginine + H2O => ornithine + urea [ARG1] IEA Mus musculus 15377 R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Mus musculus 15377 R-MMU-70599 https://reactome.org/PathwayBrowser/#/R-MMU-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Mus musculus 15377 R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Mus musculus 15377 R-MMU-70609 https://reactome.org/PathwayBrowser/#/R-MMU-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Mus musculus 15377 R-MMU-70679 https://reactome.org/PathwayBrowser/#/R-MMU-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Mus musculus 15377 R-MMU-70785 https://reactome.org/PathwayBrowser/#/R-MMU-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Mus musculus 15377 R-MMU-70870 https://reactome.org/PathwayBrowser/#/R-MMU-70870 ECHS1 hydrates methacrylyl-CoA IEA Mus musculus 15377 R-MMU-70881 https://reactome.org/PathwayBrowser/#/R-MMU-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Mus musculus 15377 R-MMU-70903 https://reactome.org/PathwayBrowser/#/R-MMU-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Mus musculus 15377 R-MMU-70906 https://reactome.org/PathwayBrowser/#/R-MMU-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Mus musculus 15377 R-MMU-70938 https://reactome.org/PathwayBrowser/#/R-MMU-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Mus musculus 15377 R-MMU-70940 https://reactome.org/PathwayBrowser/#/R-MMU-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Mus musculus 15377 R-MMU-70941 https://reactome.org/PathwayBrowser/#/R-MMU-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Mus musculus 15377 R-MMU-70975 https://reactome.org/PathwayBrowser/#/R-MMU-70975 CS acetylates OA to citrate IEA Mus musculus 15377 R-MMU-70982 https://reactome.org/PathwayBrowser/#/R-MMU-70982 FH tetramer hydrates fumarate to L-malate IEA Mus musculus 15377 R-MMU-71146 https://reactome.org/PathwayBrowser/#/R-MMU-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Mus musculus 15377 R-MMU-71181 https://reactome.org/PathwayBrowser/#/R-MMU-71181 FAH cleaves 4FAA IEA Mus musculus 15377 R-MMU-71196 https://reactome.org/PathwayBrowser/#/R-MMU-71196 N-formylkynurenine + H2O => kynurenine + formate [mouse] TAS Mus musculus 15377 R-MMU-71200 https://reactome.org/PathwayBrowser/#/R-MMU-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Mus musculus 15377 R-MMU-71217 https://reactome.org/PathwayBrowser/#/R-MMU-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Mus musculus 15377 R-MMU-71260 https://reactome.org/PathwayBrowser/#/R-MMU-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Mus musculus 15377 R-MMU-71296 https://reactome.org/PathwayBrowser/#/R-MMU-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Mus musculus 15377 R-MMU-71660 https://reactome.org/PathwayBrowser/#/R-MMU-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Mus musculus 15377 R-MMU-71676 https://reactome.org/PathwayBrowser/#/R-MMU-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Mus musculus 15377 R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 15377 R-MMU-71723 https://reactome.org/PathwayBrowser/#/R-MMU-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Mus musculus 15377 R-MMU-71732 https://reactome.org/PathwayBrowser/#/R-MMU-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Mus musculus 15377 R-MMU-71825 https://reactome.org/PathwayBrowser/#/R-MMU-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Mus musculus 15377 R-MMU-73571 https://reactome.org/PathwayBrowser/#/R-MMU-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Mus musculus 15377 R-MMU-73577 https://reactome.org/PathwayBrowser/#/R-MMU-73577 CAD hexamer transforms L-Gln to CAP IEA Mus musculus 15377 R-MMU-73589 https://reactome.org/PathwayBrowser/#/R-MMU-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Mus musculus 15377 R-MMU-73591 https://reactome.org/PathwayBrowser/#/R-MMU-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Mus musculus 15377 R-MMU-73596 https://reactome.org/PathwayBrowser/#/R-MMU-73596 dCMP + H2O => dUMP + NH4+ IEA Mus musculus 15377 R-MMU-73608 https://reactome.org/PathwayBrowser/#/R-MMU-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Mus musculus 15377 R-MMU-73618 https://reactome.org/PathwayBrowser/#/R-MMU-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Mus musculus 15377 R-MMU-73620 https://reactome.org/PathwayBrowser/#/R-MMU-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Mus musculus 15377 R-MMU-73647 https://reactome.org/PathwayBrowser/#/R-MMU-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Mus musculus 15377 R-MMU-73666 https://reactome.org/PathwayBrowser/#/R-MMU-73666 dUTP + H2O => dUMP + pyrophosphate IEA Mus musculus 15377 R-MMU-73792 https://reactome.org/PathwayBrowser/#/R-MMU-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Mus musculus 15377 R-MMU-73794 https://reactome.org/PathwayBrowser/#/R-MMU-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Mus musculus 15377 R-MMU-73797 https://reactome.org/PathwayBrowser/#/R-MMU-73797 FAICAR => IMP + H2O IEA Mus musculus 15377 R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 15377 R-MMU-73815 https://reactome.org/PathwayBrowser/#/R-MMU-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Mus musculus 15377 R-MMU-74059 https://reactome.org/PathwayBrowser/#/R-MMU-74059 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 15377 R-MMU-74241 https://reactome.org/PathwayBrowser/#/R-MMU-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Mus musculus 15377 R-MMU-74247 https://reactome.org/PathwayBrowser/#/R-MMU-74247 XDH oxidizes hypoxanthine to form xanthine IEA Mus musculus 15377 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 15377 R-MMU-74255 https://reactome.org/PathwayBrowser/#/R-MMU-74255 Guanine + H2O => Xanthine + NH4+ IEA Mus musculus 15377 R-MMU-74258 https://reactome.org/PathwayBrowser/#/R-MMU-74258 XDH oxidizes xanthine to form urate IEA Mus musculus 15377 R-MMU-74733 https://reactome.org/PathwayBrowser/#/R-MMU-74733 Insulin receptor de-phosphorylation IEA Mus musculus 15377 R-MMU-74948 https://reactome.org/PathwayBrowser/#/R-MMU-74948 PP2A dephosphorylates p-RHO to RHO IEA Mus musculus 15377 R-MMU-75872 https://reactome.org/PathwayBrowser/#/R-MMU-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Mus musculus 15377 R-MMU-75899 https://reactome.org/PathwayBrowser/#/R-MMU-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Mus musculus 15377 R-MMU-76031 https://reactome.org/PathwayBrowser/#/R-MMU-76031 2 H2O2 => O2 + 2 H2O IEA Mus musculus 15377 R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 15377 R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 15377 R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 15377 R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 15377 R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 15377 R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 15377 R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 15377 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 15377 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 15377 R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 15377 R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 15377 R-MMU-76590 https://reactome.org/PathwayBrowser/#/R-MMU-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Mus musculus 15377 R-MMU-77256 https://reactome.org/PathwayBrowser/#/R-MMU-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Mus musculus 15377 R-MMU-77277 https://reactome.org/PathwayBrowser/#/R-MMU-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Mus musculus 15377 R-MMU-77301 https://reactome.org/PathwayBrowser/#/R-MMU-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Mus musculus 15377 R-MMU-77314 https://reactome.org/PathwayBrowser/#/R-MMU-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Mus musculus 15377 R-MMU-77325 https://reactome.org/PathwayBrowser/#/R-MMU-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Mus musculus 15377 R-MMU-77333 https://reactome.org/PathwayBrowser/#/R-MMU-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Mus musculus 15377 R-MMU-77344 https://reactome.org/PathwayBrowser/#/R-MMU-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Mus musculus 15377 R-MMU-77614 https://reactome.org/PathwayBrowser/#/R-MMU-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Mus musculus 15377 R-MMU-77615 https://reactome.org/PathwayBrowser/#/R-MMU-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Mus musculus 15377 R-MMU-83677 https://reactome.org/PathwayBrowser/#/R-MMU-83677 C4 deamination of cytidine IEA Mus musculus 15377 R-MMU-870437 https://reactome.org/PathwayBrowser/#/R-MMU-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Mus musculus 15377 R-MMU-877301 https://reactome.org/PathwayBrowser/#/R-MMU-877301 Dephosphorylation of Jaks by Ptps TAS Mus musculus 15377 R-MMU-8847424 https://reactome.org/PathwayBrowser/#/R-MMU-8847424 Gdpd1 hydrolyzes LysoPtdCho TAS Mus musculus 15377 R-MMU-8847427 https://reactome.org/PathwayBrowser/#/R-MMU-8847427 Gdpd3 hydrolyzes LysoPtdCho TAS Mus musculus 15377 R-MMU-8847904 https://reactome.org/PathwayBrowser/#/R-MMU-8847904 Pnpla7 hydrolyzes LysoPtdCho TAS Mus musculus 15377 R-MMU-8848053 https://reactome.org/PathwayBrowser/#/R-MMU-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Mus musculus 15377 R-MMU-8848215 https://reactome.org/PathwayBrowser/#/R-MMU-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Mus musculus 15377 R-MMU-8848339 https://reactome.org/PathwayBrowser/#/R-MMU-8848339 PNPLA5 hydrolyzes TAG IEA Mus musculus 15377 R-MMU-8848484 https://reactome.org/PathwayBrowser/#/R-MMU-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Mus musculus 15377 R-MMU-8849435 https://reactome.org/PathwayBrowser/#/R-MMU-8849435 PTPN1 dephosphorylates PTK6 IEA Mus musculus 15377 R-MMU-8849847 https://reactome.org/PathwayBrowser/#/R-MMU-8849847 St14 hydrolyzes and activates Klk5 TAS Mus musculus 15377 R-MMU-8849857 https://reactome.org/PathwayBrowser/#/R-MMU-8849857 KLK5 cleaves and activates CELA2 IEA Mus musculus 15377 R-MMU-8849969 https://reactome.org/PathwayBrowser/#/R-MMU-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Mus musculus 15377 R-MMU-8850594 https://reactome.org/PathwayBrowser/#/R-MMU-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Mus musculus 15377 R-MMU-8850831 https://reactome.org/PathwayBrowser/#/R-MMU-8850831 KLK5 cleaves and activates KLK8 IEA Mus musculus 15377 R-MMU-8850846 https://reactome.org/PathwayBrowser/#/R-MMU-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-MMU-8850854 https://reactome.org/PathwayBrowser/#/R-MMU-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-MMU-8851110 https://reactome.org/PathwayBrowser/#/R-MMU-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-MMU-8851129 https://reactome.org/PathwayBrowser/#/R-MMU-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-MMU-8852200 https://reactome.org/PathwayBrowser/#/R-MMU-8852200 Inactivation of LCK by PTPN22 IEA Mus musculus 15377 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 15377 R-MMU-8853686 https://reactome.org/PathwayBrowser/#/R-MMU-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Mus musculus 15377 R-MMU-8854173 https://reactome.org/PathwayBrowser/#/R-MMU-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Mus musculus 15377 R-MMU-8854255 https://reactome.org/PathwayBrowser/#/R-MMU-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Mus musculus 15377 R-MMU-8854329 https://reactome.org/PathwayBrowser/#/R-MMU-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Mus musculus 15377 R-MMU-8854604 https://reactome.org/PathwayBrowser/#/R-MMU-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Mus musculus 15377 R-MMU-8854612 https://reactome.org/PathwayBrowser/#/R-MMU-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Mus musculus 15377 R-MMU-8855381 https://reactome.org/PathwayBrowser/#/R-MMU-8855381 PTPN22 dephosphorylates ZAP70 IEA Mus musculus 15377 R-MMU-8855490 https://reactome.org/PathwayBrowser/#/R-MMU-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Mus musculus 15377 R-MMU-8855825 https://reactome.org/PathwayBrowser/#/R-MMU-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Mus musculus 15377 R-MMU-8856951 https://reactome.org/PathwayBrowser/#/R-MMU-8856951 PP2A demethylation by PPME1 IEA Mus musculus 15377 R-MMU-8862184 https://reactome.org/PathwayBrowser/#/R-MMU-8862184 USP48 cleaves polyubiquitin IEA Mus musculus 15377 R-MMU-8862320 https://reactome.org/PathwayBrowser/#/R-MMU-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Mus musculus 15377 R-MMU-8863416 https://reactome.org/PathwayBrowser/#/R-MMU-8863416 Calpain 1 or Calpain 2 cleaves Cdk5r1 (p35) TAS Mus musculus 15377 R-MMU-8863804 https://reactome.org/PathwayBrowser/#/R-MMU-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Mus musculus 15377 R-MMU-8864029 https://reactome.org/PathwayBrowser/#/R-MMU-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Mus musculus 15377 R-MMU-8864036 https://reactome.org/PathwayBrowser/#/R-MMU-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Mus musculus 15377 R-MMU-8864125 https://reactome.org/PathwayBrowser/#/R-MMU-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Mus musculus 15377 R-MMU-8865667 https://reactome.org/PathwayBrowser/#/R-MMU-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Mus musculus 15377 R-MMU-8866405 https://reactome.org/PathwayBrowser/#/R-MMU-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 15377 R-MMU-8866542 https://reactome.org/PathwayBrowser/#/R-MMU-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Mus musculus 15377 R-MMU-8866601 https://reactome.org/PathwayBrowser/#/R-MMU-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Mus musculus 15377 R-MMU-8867047 https://reactome.org/PathwayBrowser/#/R-MMU-8867047 PTPN3 dephosphorylates EPS15 IEA Mus musculus 15377 R-MMU-8867344 https://reactome.org/PathwayBrowser/#/R-MMU-8867344 OMA1 hydrolyses OPA1 IEA Mus musculus 15377 R-MMU-8867658 https://reactome.org/PathwayBrowser/#/R-MMU-8867658 PTPN3 dephosphorylates MAPK12 IEA Mus musculus 15377 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 15377 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 15377 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 15377 R-MMU-8869206 https://reactome.org/PathwayBrowser/#/R-MMU-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Mus musculus 15377 R-MMU-8869425 https://reactome.org/PathwayBrowser/#/R-MMU-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Mus musculus 15377 R-MMU-8869456 https://reactome.org/PathwayBrowser/#/R-MMU-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Mus musculus 15377 R-MMU-8869506 https://reactome.org/PathwayBrowser/#/R-MMU-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Mus musculus 15377 R-MMU-8870346 https://reactome.org/PathwayBrowser/#/R-MMU-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Mus musculus 15377 R-MMU-8874435 https://reactome.org/PathwayBrowser/#/R-MMU-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Mus musculus 15377 R-MMU-8875443 https://reactome.org/PathwayBrowser/#/R-MMU-8875443 USP8 deubiquitinates LRIG1 IEA Mus musculus 15377 R-MMU-8878581 https://reactome.org/PathwayBrowser/#/R-MMU-8878581 TYRP1 oxidises DHICA to IQCA IEA Mus musculus 15377 R-MMU-8878654 https://reactome.org/PathwayBrowser/#/R-MMU-8878654 ACP6 hydrolyses MYS-LPA IEA Mus musculus 15377 R-MMU-8878787 https://reactome.org/PathwayBrowser/#/R-MMU-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Mus musculus 15377 R-MMU-888548 https://reactome.org/PathwayBrowser/#/R-MMU-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Mus musculus 15377 R-MMU-8932633 https://reactome.org/PathwayBrowser/#/R-MMU-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Mus musculus 15377 R-MMU-8933328 https://reactome.org/PathwayBrowser/#/R-MMU-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Mus musculus 15377 R-MMU-8933635 https://reactome.org/PathwayBrowser/#/R-MMU-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Mus musculus 15377 R-MMU-8936442 https://reactome.org/PathwayBrowser/#/R-MMU-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Mus musculus 15377 R-MMU-8937442 https://reactome.org/PathwayBrowser/#/R-MMU-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Mus musculus 15377 R-MMU-8937767 https://reactome.org/PathwayBrowser/#/R-MMU-8937767 PTPN11 dephosphorylates RUNX1 IEA Mus musculus 15377 R-MMU-8938076 https://reactome.org/PathwayBrowser/#/R-MMU-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Mus musculus 15377 R-MMU-8940070 https://reactome.org/PathwayBrowser/#/R-MMU-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Mus musculus 15377 R-MMU-8940074 https://reactome.org/PathwayBrowser/#/R-MMU-8940074 NT5E:Zn2+ hydrolyses NMN IEA Mus musculus 15377 R-MMU-8940388 https://reactome.org/PathwayBrowser/#/R-MMU-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Mus musculus 15377 R-MMU-8943279 https://reactome.org/PathwayBrowser/#/R-MMU-8943279 GGT dimers hydrolyse GSH IEA Mus musculus 15377 R-MMU-8952137 https://reactome.org/PathwayBrowser/#/R-MMU-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Mus musculus 15377 R-MMU-8952251 https://reactome.org/PathwayBrowser/#/R-MMU-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Mus musculus 15377 R-MMU-8952903 https://reactome.org/PathwayBrowser/#/R-MMU-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Mus musculus 15377 R-MMU-8953339 https://reactome.org/PathwayBrowser/#/R-MMU-8953339 DNPH1 hydrolyses dGMP IEA Mus musculus 15377 R-MMU-8953499 https://reactome.org/PathwayBrowser/#/R-MMU-8953499 IMPAD1 hydrolyses PAP to AMP IEA Mus musculus 15377 R-MMU-8954398 https://reactome.org/PathwayBrowser/#/R-MMU-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Mus musculus 15377 R-MMU-8955817 https://reactome.org/PathwayBrowser/#/R-MMU-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Mus musculus 15377 R-MMU-8959510 https://reactome.org/PathwayBrowser/#/R-MMU-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Mus musculus 15377 R-MMU-8979996 https://reactome.org/PathwayBrowser/#/R-MMU-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Mus musculus 15377 R-MMU-8980228 https://reactome.org/PathwayBrowser/#/R-MMU-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Mus musculus 15377 R-MMU-8981637 https://reactome.org/PathwayBrowser/#/R-MMU-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Mus musculus 15377 R-MMU-8985594 https://reactome.org/PathwayBrowser/#/R-MMU-8985594 MYO9B inactivates RHOA IEA Mus musculus 15377 R-MMU-8986083 https://reactome.org/PathwayBrowser/#/R-MMU-8986083 USP33 deubiquitinates ROBO1 IEA Mus musculus 15377 R-MMU-9008822 https://reactome.org/PathwayBrowser/#/R-MMU-9008822 PPM1D dephosphorylates RUNX2 IEA Mus musculus 15377 R-MMU-9009950 https://reactome.org/PathwayBrowser/#/R-MMU-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Mus musculus 15377 R-MMU-9013022 https://reactome.org/PathwayBrowser/#/R-MMU-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Mus musculus 15377 R-MMU-9013111 https://reactome.org/PathwayBrowser/#/R-MMU-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Mus musculus 15377 R-MMU-9013144 https://reactome.org/PathwayBrowser/#/R-MMU-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Mus musculus 15377 R-MMU-9013161 https://reactome.org/PathwayBrowser/#/R-MMU-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Mus musculus 15377 R-MMU-9013437 https://reactome.org/PathwayBrowser/#/R-MMU-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Mus musculus 15377 R-MMU-9014295 https://reactome.org/PathwayBrowser/#/R-MMU-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Mus musculus 15377 R-MMU-9014434 https://reactome.org/PathwayBrowser/#/R-MMU-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Mus musculus 15377 R-MMU-9014627 https://reactome.org/PathwayBrowser/#/R-MMU-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Mus musculus 15377 R-MMU-9014741 https://reactome.org/PathwayBrowser/#/R-MMU-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Mus musculus 15377 R-MMU-9017488 https://reactome.org/PathwayBrowser/#/R-MMU-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Mus musculus 15377 R-MMU-9018745 https://reactome.org/PathwayBrowser/#/R-MMU-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Mus musculus 15377 R-MMU-9018806 https://reactome.org/PathwayBrowser/#/R-MMU-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Mus musculus 15377 R-MMU-9018814 https://reactome.org/PathwayBrowser/#/R-MMU-9018814 RHOT1 hydrolyzes GTP IEA Mus musculus 15377 R-MMU-9018826 https://reactome.org/PathwayBrowser/#/R-MMU-9018826 RHOT2 hydrolyzes GTP IEA Mus musculus 15377 R-MMU-9018862 https://reactome.org/PathwayBrowser/#/R-MMU-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Mus musculus 15377 R-MMU-9018868 https://reactome.org/PathwayBrowser/#/R-MMU-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Mus musculus 15377 R-MMU-9018877 https://reactome.org/PathwayBrowser/#/R-MMU-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Mus musculus 15377 R-MMU-9018895 https://reactome.org/PathwayBrowser/#/R-MMU-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Mus musculus 15377 R-MMU-9020252 https://reactome.org/PathwayBrowser/#/R-MMU-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Mus musculus 15377 R-MMU-9020253 https://reactome.org/PathwayBrowser/#/R-MMU-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Mus musculus 15377 R-MMU-9020257 https://reactome.org/PathwayBrowser/#/R-MMU-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Mus musculus 15377 R-MMU-9020258 https://reactome.org/PathwayBrowser/#/R-MMU-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Mus musculus 15377 R-MMU-9020270 https://reactome.org/PathwayBrowser/#/R-MMU-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Mus musculus 15377 R-MMU-9020271 https://reactome.org/PathwayBrowser/#/R-MMU-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Mus musculus 15377 R-MMU-9020273 https://reactome.org/PathwayBrowser/#/R-MMU-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Mus musculus 15377 R-MMU-9024890 https://reactome.org/PathwayBrowser/#/R-MMU-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Mus musculus 15377 R-MMU-9027043 https://reactome.org/PathwayBrowser/#/R-MMU-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Mus musculus 15377 R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 15377 R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 15377 R-MMU-9032476 https://reactome.org/PathwayBrowser/#/R-MMU-9032476 Epor-associated Plcg hydrolyzes 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate TAS Mus musculus 15377 R-MMU-9033491 https://reactome.org/PathwayBrowser/#/R-MMU-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Mus musculus 15377 R-MMU-9033520 https://reactome.org/PathwayBrowser/#/R-MMU-9033520 TYSND1 cleaves TYSND1 IEA Mus musculus 15377 R-MMU-9033995 https://reactome.org/PathwayBrowser/#/R-MMU-9033995 Tysnd1 cleaves Agps TAS Mus musculus 15377 R-MMU-9034001 https://reactome.org/PathwayBrowser/#/R-MMU-9034001 Tysnd1 cleaves Phyh TAS Mus musculus 15377 R-MMU-9034335 https://reactome.org/PathwayBrowser/#/R-MMU-9034335 Tysnd1 cleaves Scp2 TAS Mus musculus 15377 R-MMU-9034351 https://reactome.org/PathwayBrowser/#/R-MMU-9034351 Tysnd1 cleaves Hsd17b4 TAS Mus musculus 15377 R-MMU-9034356 https://reactome.org/PathwayBrowser/#/R-MMU-9034356 Tysnd1 cleaves Acaa1a TAS Mus musculus 15377 R-MMU-9034539 https://reactome.org/PathwayBrowser/#/R-MMU-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Mus musculus 15377 R-MMU-9036727 https://reactome.org/PathwayBrowser/#/R-MMU-9036727 GAA hydrolyzes lysosomal glycogen IEA Mus musculus 15377 R-MMU-9037761 https://reactome.org/PathwayBrowser/#/R-MMU-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Mus musculus 15377 R-MMU-917841 https://reactome.org/PathwayBrowser/#/R-MMU-917841 Acidification of Tf:TfR1 containing endosome IEA Mus musculus 15377 R-MMU-917891 https://reactome.org/PathwayBrowser/#/R-MMU-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Mus musculus 15377 R-MMU-917933 https://reactome.org/PathwayBrowser/#/R-MMU-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Mus musculus 15377 R-MMU-917979 https://reactome.org/PathwayBrowser/#/R-MMU-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Mus musculus 15377 R-MMU-936802 https://reactome.org/PathwayBrowser/#/R-MMU-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Mus musculus 15377 R-MMU-936883 https://reactome.org/PathwayBrowser/#/R-MMU-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Mus musculus 15377 R-MMU-936895 https://reactome.org/PathwayBrowser/#/R-MMU-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Mus musculus 15377 R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 15377 R-MMU-937311 https://reactome.org/PathwayBrowser/#/R-MMU-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Mus musculus 15377 R-MMU-939763 https://reactome.org/PathwayBrowser/#/R-MMU-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Mus musculus 15377 R-MMU-947531 https://reactome.org/PathwayBrowser/#/R-MMU-947531 Molybdenum ion transfer onto molybdopterin IEA Mus musculus 15377 R-MMU-947535 https://reactome.org/PathwayBrowser/#/R-MMU-947535 Cyclisation of GTP to precursor Z IEA Mus musculus 15377 R-MMU-947591 https://reactome.org/PathwayBrowser/#/R-MMU-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Mus musculus 15377 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 15377 R-MMU-9620103 https://reactome.org/PathwayBrowser/#/R-MMU-9620103 ALDH2 transforms GTN to NO IEA Mus musculus 15377 R-MMU-9624893 https://reactome.org/PathwayBrowser/#/R-MMU-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Mus musculus 15377 R-MMU-9629675 https://reactome.org/PathwayBrowser/#/R-MMU-9629675 PDE3A hydrolyses cAMP to AMP IEA Mus musculus 15377 R-MMU-9635739 https://reactome.org/PathwayBrowser/#/R-MMU-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Mus musculus 15377 R-MMU-9638046 https://reactome.org/PathwayBrowser/#/R-MMU-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 15377 R-MMU-9638075 https://reactome.org/PathwayBrowser/#/R-MMU-9638075 HEXB cleaves the terminal GalNAc from DS IEA Mus musculus 15377 R-MMU-9638076 https://reactome.org/PathwayBrowser/#/R-MMU-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Mus musculus 15377 R-MMU-9638078 https://reactome.org/PathwayBrowser/#/R-MMU-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Mus musculus 15377 R-MMU-9638120 https://reactome.org/PathwayBrowser/#/R-MMU-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 15377 R-MMU-9644869 https://reactome.org/PathwayBrowser/#/R-MMU-9644869 p-S54-PDE4B hydrolyses cAMP IEA Mus musculus 15377 R-MMU-9647994 https://reactome.org/PathwayBrowser/#/R-MMU-9647994 RAS proteins are depalmitoylated IEA Mus musculus 15377 R-MMU-965067 https://reactome.org/PathwayBrowser/#/R-MMU-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Mus musculus 15377 R-MMU-965079 https://reactome.org/PathwayBrowser/#/R-MMU-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Mus musculus 15377 R-MMU-9653514 https://reactome.org/PathwayBrowser/#/R-MMU-9653514 USP17L2 deubiquitinates RCE1 IEA Mus musculus 15377 R-MMU-9656891 https://reactome.org/PathwayBrowser/#/R-MMU-9656891 OPN1SW binds 11cRAL IEA Mus musculus 15377 R-MMU-9656893 https://reactome.org/PathwayBrowser/#/R-MMU-9656893 OPN1MW binds 11cRAL IEA Mus musculus 15377 R-MMU-9658445 https://reactome.org/PathwayBrowser/#/R-MMU-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Mus musculus 15377 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 15377 R-MMU-9661417 https://reactome.org/PathwayBrowser/#/R-MMU-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 15377 R-MMU-9667952 https://reactome.org/PathwayBrowser/#/R-MMU-9667952 ANKLE2 is deacetylated by SIRT2 IEA Mus musculus 15377 R-MMU-9668419 https://reactome.org/PathwayBrowser/#/R-MMU-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Mus musculus 15377 R-MMU-9673053 https://reactome.org/PathwayBrowser/#/R-MMU-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Mus musculus 15377 R-MMU-9673054 https://reactome.org/PathwayBrowser/#/R-MMU-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Mus musculus 15377 R-MMU-9674127 https://reactome.org/PathwayBrowser/#/R-MMU-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Mus musculus 15377 R-MMU-9682158 https://reactome.org/PathwayBrowser/#/R-MMU-9682158 Csf1r-associated Plcg2 hydrolyzes phosphatidylcholine yielding choline phosphate and 1,2-diacylglycerol TAS Mus musculus 15377 R-MMU-9686524 https://reactome.org/PathwayBrowser/#/R-MMU-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Mus musculus 15377 R-MMU-9693282 https://reactome.org/PathwayBrowser/#/R-MMU-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Mus musculus 15377 R-MMU-9698408 https://reactome.org/PathwayBrowser/#/R-MMU-9698408 PTPRJ dephosphorylates active FLT3 IEA Mus musculus 15377 R-MMU-9700200 https://reactome.org/PathwayBrowser/#/R-MMU-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Mus musculus 15377 R-MMU-9701507 https://reactome.org/PathwayBrowser/#/R-MMU-9701507 PTPN6 dephosphorylates JAK3 IEA Mus musculus 15377 R-MMU-9701565 https://reactome.org/PathwayBrowser/#/R-MMU-9701565 HDACs deacetylate p-STAT3 dimers IEA Mus musculus 15377 R-MMU-9705507 https://reactome.org/PathwayBrowser/#/R-MMU-9705507 PDE3B hydrolyses cAMP to AMP IEA Mus musculus 15377 R-MMU-9706399 https://reactome.org/PathwayBrowser/#/R-MMU-9706399 RHOBTB3 hydrolyzes ATP IEA Mus musculus 15377 R-MMU-9708261 https://reactome.org/PathwayBrowser/#/R-MMU-9708261 PDE4A hydrolyses cAMP to AMP IEA Mus musculus 15377 R-MMU-9709360 https://reactome.org/PathwayBrowser/#/R-MMU-9709360 H2O2 reduces MetHb IEA Mus musculus 15377 R-MMU-9727198 https://reactome.org/PathwayBrowser/#/R-MMU-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Mus musculus 15377 R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 15377 R-MMU-9727349 https://reactome.org/PathwayBrowser/#/R-MMU-9727349 XDH dehydrogenates xanthine to form urate IEA Mus musculus 15377 R-MMU-9727567 https://reactome.org/PathwayBrowser/#/R-MMU-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Mus musculus 15377 R-MMU-9731228 https://reactome.org/PathwayBrowser/#/R-MMU-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Mus musculus 15377 R-MMU-9731590 https://reactome.org/PathwayBrowser/#/R-MMU-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Mus musculus 15377 R-MMU-9731613 https://reactome.org/PathwayBrowser/#/R-MMU-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Mus musculus 15377 R-MMU-9731632 https://reactome.org/PathwayBrowser/#/R-MMU-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Mus musculus 15377 R-MMU-9731661 https://reactome.org/PathwayBrowser/#/R-MMU-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Mus musculus 15377 R-MMU-9748945 https://reactome.org/PathwayBrowser/#/R-MMU-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Mus musculus 15377 R-MMU-9748957 https://reactome.org/PathwayBrowser/#/R-MMU-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Mus musculus 15377 R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 15377 R-MMU-9749609 https://reactome.org/PathwayBrowser/#/R-MMU-9749609 BCHE hydrolyzes ASA- IEA Mus musculus 15377 R-MMU-9749647 https://reactome.org/PathwayBrowser/#/R-MMU-9749647 CES2 hydrolyzes ASA- IEA Mus musculus 15377 R-MMU-9749792 https://reactome.org/PathwayBrowser/#/R-MMU-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Mus musculus 15377 R-MMU-9749986 https://reactome.org/PathwayBrowser/#/R-MMU-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Mus musculus 15377 R-MMU-9750016 https://reactome.org/PathwayBrowser/#/R-MMU-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Mus musculus 15377 R-MMU-9750546 https://reactome.org/PathwayBrowser/#/R-MMU-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 15377 R-MMU-9750555 https://reactome.org/PathwayBrowser/#/R-MMU-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Mus musculus 15377 R-MMU-9750617 https://reactome.org/PathwayBrowser/#/R-MMU-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 15377 R-MMU-9750656 https://reactome.org/PathwayBrowser/#/R-MMU-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Mus musculus 15377 R-MMU-9750942 https://reactome.org/PathwayBrowser/#/R-MMU-9750942 USP14 deubiquitinates NLRC5 IEA Mus musculus 15377 R-MMU-9753278 https://reactome.org/PathwayBrowser/#/R-MMU-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 15377 R-MMU-9753280 https://reactome.org/PathwayBrowser/#/R-MMU-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Mus musculus 15377 R-MMU-9753283 https://reactome.org/PathwayBrowser/#/R-MMU-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 15377 R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 15377 R-MMU-9753285 https://reactome.org/PathwayBrowser/#/R-MMU-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Mus musculus 15377 R-MMU-9753632 https://reactome.org/PathwayBrowser/#/R-MMU-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Mus musculus 15377 R-MMU-9753634 https://reactome.org/PathwayBrowser/#/R-MMU-9753634 GGT dimers hydrolyse APAP-SG IEA Mus musculus 15377 R-MMU-9753944 https://reactome.org/PathwayBrowser/#/R-MMU-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Mus musculus 15377 R-MMU-9754964 https://reactome.org/PathwayBrowser/#/R-MMU-9754964 ADA deamidates RBV IEA Mus musculus 15377 R-MMU-9755030 https://reactome.org/PathwayBrowser/#/R-MMU-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Mus musculus 15377 R-MMU-9755078 https://reactome.org/PathwayBrowser/#/R-MMU-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Mus musculus 15377 R-MMU-975593 https://reactome.org/PathwayBrowser/#/R-MMU-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Mus musculus 15377 R-MMU-975594 https://reactome.org/PathwayBrowser/#/R-MMU-975594 PLB1 hydrolyses RPALM to atROL IEA Mus musculus 15377 R-MMU-9756138 https://reactome.org/PathwayBrowser/#/R-MMU-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Mus musculus 15377 R-MMU-9756162 https://reactome.org/PathwayBrowser/#/R-MMU-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Mus musculus 15377 R-MMU-9756169 https://reactome.org/PathwayBrowser/#/R-MMU-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Mus musculus 15377 R-MMU-9756177 https://reactome.org/PathwayBrowser/#/R-MMU-9756177 PON1,3 hydrolyse ATVL to ATV IEA Mus musculus 15377 R-MMU-9756180 https://reactome.org/PathwayBrowser/#/R-MMU-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Mus musculus 15377 R-MMU-9758674 https://reactome.org/PathwayBrowser/#/R-MMU-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Mus musculus 15377 R-MMU-9759206 https://reactome.org/PathwayBrowser/#/R-MMU-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Mus musculus 15377 R-MMU-9759454 https://reactome.org/PathwayBrowser/#/R-MMU-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Mus musculus 15377 R-MMU-9759461 https://reactome.org/PathwayBrowser/#/R-MMU-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Mus musculus 15377 R-MMU-977324 https://reactome.org/PathwayBrowser/#/R-MMU-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Mus musculus 15377 R-MMU-9794120 https://reactome.org/PathwayBrowser/#/R-MMU-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Mus musculus 15377 R-MMU-9794572 https://reactome.org/PathwayBrowser/#/R-MMU-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Mus musculus 15377 R-MMU-983144 https://reactome.org/PathwayBrowser/#/R-MMU-983144 Transport of Antigen peptide in to ER IEA Mus musculus 15377 R-MMU-983422 https://reactome.org/PathwayBrowser/#/R-MMU-983422 Disassembly of COPII coated vesicle IEA Mus musculus 15377 R-MMU-9837342 https://reactome.org/PathwayBrowser/#/R-MMU-9837342 Nudt8 hydrolyzes CoA-SH to PPANT TAS Mus musculus 15377 R-MMU-9837419 https://reactome.org/PathwayBrowser/#/R-MMU-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Mus musculus 15377 R-MMU-9838004 https://reactome.org/PathwayBrowser/#/R-MMU-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Mus musculus 15377 R-MMU-9838081 https://reactome.org/PathwayBrowser/#/R-MMU-9838081 LONP1 degrades mitochondrial matrix proteins IEA Mus musculus 15377 R-MMU-9838289 https://reactome.org/PathwayBrowser/#/R-MMU-9838289 CLPXP degrades mitochondrial matrix proteins IEA Mus musculus 15377 R-MMU-9839059 https://reactome.org/PathwayBrowser/#/R-MMU-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Mus musculus 15377 R-MMU-9839072 https://reactome.org/PathwayBrowser/#/R-MMU-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Mus musculus 15377 R-MMU-9839105 https://reactome.org/PathwayBrowser/#/R-MMU-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Mus musculus 15377 R-MMU-9839110 https://reactome.org/PathwayBrowser/#/R-MMU-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Mus musculus 15377 R-MMU-9839113 https://reactome.org/PathwayBrowser/#/R-MMU-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Mus musculus 15377 R-MMU-9840408 https://reactome.org/PathwayBrowser/#/R-MMU-9840408 OMA1 cleaves DELE1 IEA Mus musculus 15377 R-MMU-9840795 https://reactome.org/PathwayBrowser/#/R-MMU-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Mus musculus 15377 R-MMU-9840833 https://reactome.org/PathwayBrowser/#/R-MMU-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Mus musculus 15377 R-MMU-9840884 https://reactome.org/PathwayBrowser/#/R-MMU-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Mus musculus 15377 R-MMU-9840949 https://reactome.org/PathwayBrowser/#/R-MMU-9840949 ARSA removes sulfate from SM3 IEA Mus musculus 15377 R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 15377 R-MMU-9843721 https://reactome.org/PathwayBrowser/#/R-MMU-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Mus musculus 15377 R-MMU-9853385 https://reactome.org/PathwayBrowser/#/R-MMU-9853385 PPP1CC dephosphorylates PLK1 IEA Mus musculus 15377 R-MMU-9861626 https://reactome.org/PathwayBrowser/#/R-MMU-9861626 SIRT4 cleaves lipoyl from DLAT IEA Mus musculus 15377 R-MMU-9861725 https://reactome.org/PathwayBrowser/#/R-MMU-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Mus musculus 15377 R-MMU-997309 https://reactome.org/PathwayBrowser/#/R-MMU-997309 Dephosphorylation of STAT1 by SHP2 IEA Mus musculus 15377 R-MMU-997311 https://reactome.org/PathwayBrowser/#/R-MMU-997311 Dephosphorylation of TYK2 by PTP1B IEA Mus musculus 15377 R-MMU-997314 https://reactome.org/PathwayBrowser/#/R-MMU-997314 Dephosphorylation of JAK1 by SHP1 IEA Mus musculus 15377 R-MMU-997326 https://reactome.org/PathwayBrowser/#/R-MMU-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Mus musculus 15377 R-MTU-868608 https://reactome.org/PathwayBrowser/#/R-MTU-868608 Trehalose-6-phosphate is hydrolyzed to trehalose TAS Mycobacterium tuberculosis 15377 R-MTU-868657 https://reactome.org/PathwayBrowser/#/R-MTU-868657 Glucanotrehalose is hydrolyzed to 1,4-alpha-glucan and trehalose TAS Mycobacterium tuberculosis 15377 R-MTU-879274 https://reactome.org/PathwayBrowser/#/R-MTU-879274 acetylglucosamine-inositol-phosphate is dephosphorylated TAS Mycobacterium tuberculosis 15377 R-MTU-879281 https://reactome.org/PathwayBrowser/#/R-MTU-879281 mycothiol is cleaved to acetylcysteine and glucosaminylinositol TAS Mycobacterium tuberculosis 15377 R-MTU-879293 https://reactome.org/PathwayBrowser/#/R-MTU-879293 formylmycothiol hydrolyzes into mycothiol and formate TAS Mycobacterium tuberculosis 15377 R-MTU-879298 https://reactome.org/PathwayBrowser/#/R-MTU-879298 acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate TAS Mycobacterium tuberculosis 15377 R-MTU-879311 https://reactome.org/PathwayBrowser/#/R-MTU-879311 mycothiol S-conjugate is cleaved into mercapturic acid and GlcN-Ins TAS Mycobacterium tuberculosis 15377 R-MTU-879327 https://reactome.org/PathwayBrowser/#/R-MTU-879327 acetylglucosamine-inositol is deacetylated by Mca TAS Mycobacterium tuberculosis 15377 R-MTU-936583 https://reactome.org/PathwayBrowser/#/R-MTU-936583 APS is phosphorylated to PAPS TAS Mycobacterium tuberculosis 15377 R-MTU-936631 https://reactome.org/PathwayBrowser/#/R-MTU-936631 sulfate uptake in the cytosol TAS Mycobacterium tuberculosis 15377 R-MTU-936659 https://reactome.org/PathwayBrowser/#/R-MTU-936659 PAPS is dephosphorylated to APS TAS Mycobacterium tuberculosis 15377 R-MTU-936703 https://reactome.org/PathwayBrowser/#/R-MTU-936703 sulfite is reduced to sulfide TAS Mycobacterium tuberculosis 15377 R-MTU-936747 https://reactome.org/PathwayBrowser/#/R-MTU-936747 cleavage of L-cysteine from carrier protein TAS Mycobacterium tuberculosis 15377 R-MTU-937192 https://reactome.org/PathwayBrowser/#/R-MTU-937192 Cysteine from cystathionine and vice versa TAS Mycobacterium tuberculosis 15377 R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 15377 R-MTU-964851 https://reactome.org/PathwayBrowser/#/R-MTU-964851 Dehydratation of DHQ yields DHS TAS Mycobacterium tuberculosis 15377 R-MTU-964912 https://reactome.org/PathwayBrowser/#/R-MTU-964912 DHAP from Ery4P and PEP TAS Mycobacterium tuberculosis 15377 R-NUL-1236944 https://reactome.org/PathwayBrowser/#/R-NUL-1236944 Translocation of antigenic peptides back to phagosomes via TAP TAS Gallus gallus 15377 R-NUL-2167872 https://reactome.org/PathwayBrowser/#/R-NUL-2167872 PP1CC dephosphorylates TGFBR1 TAS Homo sapiens 15377 R-NUL-2179313 https://reactome.org/PathwayBrowser/#/R-NUL-2179313 Uchl5 deubiquitinates TGFBR1 TAS Homo sapiens 15377 R-NUL-8955728 https://reactome.org/PathwayBrowser/#/R-NUL-8955728 TTCP hydrolyzes the terminal L-Tyr residue from alpha-tubulin TAS Bos taurus 15377 R-NUL-9023165 https://reactome.org/PathwayBrowser/#/R-NUL-9023165 Pcsk1 (rat) cleaves human proinsulin to yield Insulin(25-56) and Insulin(57-110) TAS Homo sapiens 15377 R-NUL-9023166 https://reactome.org/PathwayBrowser/#/R-NUL-9023166 Carboxypeptidase E (rat Carboxypeptidase H) cleaves Insulin(25-56) to yield Insulin(25-54) TAS Homo sapiens 15377 R-NUL-9023180 https://reactome.org/PathwayBrowser/#/R-NUL-9023180 Pcsk2 (rat) cleaves human Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) TAS Homo sapiens 15377 R-NUL-9034341 https://reactome.org/PathwayBrowser/#/R-NUL-9034341 Tysnd1 cleaves Acox1 TAS Mus musculus 15377 R-NUL-9603754 https://reactome.org/PathwayBrowser/#/R-NUL-9603754 PTPRS dephosphorylates Ntrk3 TAS Gallus gallus 15377 R-NUL-9603766 https://reactome.org/PathwayBrowser/#/R-NUL-9603766 PTPRO dephosphorylate NTRK3 TAS Gallus gallus 15377 R-NUL-9717576 https://reactome.org/PathwayBrowser/#/R-NUL-9717576 Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG TAS Bos taurus 15377 R-OCU-189019 https://reactome.org/PathwayBrowser/#/R-OCU-189019 trehalose + H2O => 2 D-glucose TAS Oryctolagus cuniculus 15377 R-OCU-2161896 https://reactome.org/PathwayBrowser/#/R-OCU-2161896 5S-HpETE is reduced to 5S-HETE by GPX1 TAS Oryctolagus cuniculus 15377 R-PFA-111742 https://reactome.org/PathwayBrowser/#/R-PFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 15377 R-PFA-111751 https://reactome.org/PathwayBrowser/#/R-PFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 15377 R-PFA-111804 https://reactome.org/PathwayBrowser/#/R-PFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 15377 R-PFA-111955 https://reactome.org/PathwayBrowser/#/R-PFA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Plasmodium falciparum 15377 R-PFA-111962 https://reactome.org/PathwayBrowser/#/R-PFA-111962 PDE4A,C,D hydrolyse cAMP IEA Plasmodium falciparum 15377 R-PFA-1369028 https://reactome.org/PathwayBrowser/#/R-PFA-1369028 ABCAs mediate lipid efflux IEA Plasmodium falciparum 15377 R-PFA-1369052 https://reactome.org/PathwayBrowser/#/R-PFA-1369052 ABCAs mediate lipid influx IEA Plasmodium falciparum 15377 R-PFA-1369065 https://reactome.org/PathwayBrowser/#/R-PFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Plasmodium falciparum 15377 R-PFA-1454916 https://reactome.org/PathwayBrowser/#/R-PFA-1454916 The ABCC family mediates organic anion transport IEA Plasmodium falciparum 15377 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-PFA-1467466 https://reactome.org/PathwayBrowser/#/R-PFA-1467466 ABCA4 mediates atRAL transport IEA Plasmodium falciparum 15377 R-PFA-1475022 https://reactome.org/PathwayBrowser/#/R-PFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Plasmodium falciparum 15377 R-PFA-1475026 https://reactome.org/PathwayBrowser/#/R-PFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Plasmodium falciparum 15377 R-PFA-1475028 https://reactome.org/PathwayBrowser/#/R-PFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Plasmodium falciparum 15377 R-PFA-1475032 https://reactome.org/PathwayBrowser/#/R-PFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Plasmodium falciparum 15377 R-PFA-1475435 https://reactome.org/PathwayBrowser/#/R-PFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Plasmodium falciparum 15377 R-PFA-1475436 https://reactome.org/PathwayBrowser/#/R-PFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Plasmodium falciparum 15377 R-PFA-1482543 https://reactome.org/PathwayBrowser/#/R-PFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Plasmodium falciparum 15377 R-PFA-1482777 https://reactome.org/PathwayBrowser/#/R-PFA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Plasmodium falciparum 15377 R-PFA-1482811 https://reactome.org/PathwayBrowser/#/R-PFA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Plasmodium falciparum 15377 R-PFA-1483203 https://reactome.org/PathwayBrowser/#/R-PFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Plasmodium falciparum 15377 R-PFA-1606273 https://reactome.org/PathwayBrowser/#/R-PFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Plasmodium falciparum 15377 R-PFA-162425 https://reactome.org/PathwayBrowser/#/R-PFA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Plasmodium falciparum 15377 R-PFA-162857 https://reactome.org/PathwayBrowser/#/R-PFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Plasmodium falciparum 15377 R-PFA-1675824 https://reactome.org/PathwayBrowser/#/R-PFA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Plasmodium falciparum 15377 R-PFA-1675836 https://reactome.org/PathwayBrowser/#/R-PFA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-1675949 https://reactome.org/PathwayBrowser/#/R-PFA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-1675988 https://reactome.org/PathwayBrowser/#/R-PFA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-1675994 https://reactome.org/PathwayBrowser/#/R-PFA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-1676114 https://reactome.org/PathwayBrowser/#/R-PFA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Plasmodium falciparum 15377 R-PFA-1676124 https://reactome.org/PathwayBrowser/#/R-PFA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Plasmodium falciparum 15377 R-PFA-1676177 https://reactome.org/PathwayBrowser/#/R-PFA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-1676203 https://reactome.org/PathwayBrowser/#/R-PFA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-174391 https://reactome.org/PathwayBrowser/#/R-PFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Plasmodium falciparum 15377 R-PFA-1855174 https://reactome.org/PathwayBrowser/#/R-PFA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Plasmodium falciparum 15377 R-PFA-1855177 https://reactome.org/PathwayBrowser/#/R-PFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-1855213 https://reactome.org/PathwayBrowser/#/R-PFA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-1855214 https://reactome.org/PathwayBrowser/#/R-PFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Plasmodium falciparum 15377 R-PFA-1855218 https://reactome.org/PathwayBrowser/#/R-PFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Plasmodium falciparum 15377 R-PFA-1855221 https://reactome.org/PathwayBrowser/#/R-PFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-1855222 https://reactome.org/PathwayBrowser/#/R-PFA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-189406 https://reactome.org/PathwayBrowser/#/R-PFA-189406 4 PBGs bind to form HMB IEA Plasmodium falciparum 15377 R-PFA-189421 https://reactome.org/PathwayBrowser/#/R-PFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Plasmodium falciparum 15377 R-PFA-189439 https://reactome.org/PathwayBrowser/#/R-PFA-189439 ALAD condenses 2 dALAs to form PBG IEA Plasmodium falciparum 15377 R-PFA-193362 https://reactome.org/PathwayBrowser/#/R-PFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-PFA-196950 https://reactome.org/PathwayBrowser/#/R-PFA-196950 2xTRAP hydrolyzes FMN to RIB IEA Plasmodium falciparum 15377 R-PFA-197271 https://reactome.org/PathwayBrowser/#/R-PFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Plasmodium falciparum 15377 R-PFA-200661 https://reactome.org/PathwayBrowser/#/R-PFA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Plasmodium falciparum 15377 R-PFA-200740 https://reactome.org/PathwayBrowser/#/R-PFA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Plasmodium falciparum 15377 R-PFA-201035 https://reactome.org/PathwayBrowser/#/R-PFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Plasmodium falciparum 15377 R-PFA-202407 https://reactome.org/PathwayBrowser/#/R-PFA-202407 PLC-gamma1 hydrolyses PIP2 IEA Plasmodium falciparum 15377 R-PFA-203797 https://reactome.org/PathwayBrowser/#/R-PFA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Plasmodium falciparum 15377 R-PFA-2046088 https://reactome.org/PathwayBrowser/#/R-PFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Plasmodium falciparum 15377 R-PFA-2046094 https://reactome.org/PathwayBrowser/#/R-PFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Plasmodium falciparum 15377 R-PFA-204662 https://reactome.org/PathwayBrowser/#/R-PFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Plasmodium falciparum 15377 R-PFA-2160492 https://reactome.org/PathwayBrowser/#/R-PFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Plasmodium falciparum 15377 R-PFA-2161959 https://reactome.org/PathwayBrowser/#/R-PFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Plasmodium falciparum 15377 R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Plasmodium falciparum 15377 R-PFA-2161999 https://reactome.org/PathwayBrowser/#/R-PFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Plasmodium falciparum 15377 R-PFA-2395818 https://reactome.org/PathwayBrowser/#/R-PFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Plasmodium falciparum 15377 R-PFA-2395849 https://reactome.org/PathwayBrowser/#/R-PFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Plasmodium falciparum 15377 R-PFA-2395872 https://reactome.org/PathwayBrowser/#/R-PFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Plasmodium falciparum 15377 R-PFA-2408551 https://reactome.org/PathwayBrowser/#/R-PFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Plasmodium falciparum 15377 R-PFA-2509827 https://reactome.org/PathwayBrowser/#/R-PFA-2509827 ITPA hydrolyses ITP to IMP IEA Plasmodium falciparum 15377 R-PFA-2509831 https://reactome.org/PathwayBrowser/#/R-PFA-2509831 ITPA hydrolyses XTP to XMP IEA Plasmodium falciparum 15377 R-PFA-2509838 https://reactome.org/PathwayBrowser/#/R-PFA-2509838 ITPA hydrolyses dITP to dIMP IEA Plasmodium falciparum 15377 R-PFA-2529015 https://reactome.org/PathwayBrowser/#/R-PFA-2529015 Dephosphorylation of CK2-modified condensin I IEA Plasmodium falciparum 15377 R-PFA-265783 https://reactome.org/PathwayBrowser/#/R-PFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-PFA-2995330 https://reactome.org/PathwayBrowser/#/R-PFA-2995330 COX10 transforms heme to heme O IEA Plasmodium falciparum 15377 R-PFA-2995334 https://reactome.org/PathwayBrowser/#/R-PFA-2995334 COX15 transforms heme O to heme A IEA Plasmodium falciparum 15377 R-PFA-3341296 https://reactome.org/PathwayBrowser/#/R-PFA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Plasmodium falciparum 15377 R-PFA-3341343 https://reactome.org/PathwayBrowser/#/R-PFA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Plasmodium falciparum 15377 R-PFA-3343700 https://reactome.org/PathwayBrowser/#/R-PFA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Plasmodium falciparum 15377 R-PFA-3697882 https://reactome.org/PathwayBrowser/#/R-PFA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Plasmodium falciparum 15377 R-PFA-3782637 https://reactome.org/PathwayBrowser/#/R-PFA-3782637 HDAC8 deacetylates histones IEA Plasmodium falciparum 15377 R-PFA-3782655 https://reactome.org/PathwayBrowser/#/R-PFA-3782655 HDAC10 deacetylates histone IEA Plasmodium falciparum 15377 R-PFA-383190 https://reactome.org/PathwayBrowser/#/R-PFA-383190 HCO3- transport through ion channel IEA Plasmodium falciparum 15377 R-PFA-418553 https://reactome.org/PathwayBrowser/#/R-PFA-418553 cAMP degradation by Phosphodiesterases IEA Plasmodium falciparum 15377 R-PFA-426043 https://reactome.org/PathwayBrowser/#/R-PFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Plasmodium falciparum 15377 R-PFA-429157 https://reactome.org/PathwayBrowser/#/R-PFA-429157 ABCC4 accumulation of dense granule contents IEA Plasmodium falciparum 15377 R-PFA-429860 https://reactome.org/PathwayBrowser/#/R-PFA-429860 DCP1-DCP2 complex decaps mRNA IEA Plasmodium falciparum 15377 R-PFA-432010 https://reactome.org/PathwayBrowser/#/R-PFA-432010 Aquaporin-1 passively transports water into cell IEA Plasmodium falciparum 15377 R-PFA-432054 https://reactome.org/PathwayBrowser/#/R-PFA-432054 Aquaporin-1 passively transports water out of cell IEA Plasmodium falciparum 15377 R-PFA-432065 https://reactome.org/PathwayBrowser/#/R-PFA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Plasmodium falciparum 15377 R-PFA-432067 https://reactome.org/PathwayBrowser/#/R-PFA-432067 Aquaporin-4 passively transports water out of cell IEA Plasmodium falciparum 15377 R-PFA-445714 https://reactome.org/PathwayBrowser/#/R-PFA-445714 Aquaporin-3 passively transports water out of cell IEA Plasmodium falciparum 15377 R-PFA-449937 https://reactome.org/PathwayBrowser/#/R-PFA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Plasmodium falciparum 15377 R-PFA-452036 https://reactome.org/PathwayBrowser/#/R-PFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Plasmodium falciparum 15377 R-PFA-504054 https://reactome.org/PathwayBrowser/#/R-PFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Plasmodium falciparum 15377 R-PFA-507868 https://reactome.org/PathwayBrowser/#/R-PFA-507868 Aquaporins passively transport water into cells IEA Plasmodium falciparum 15377 R-PFA-507870 https://reactome.org/PathwayBrowser/#/R-PFA-507870 Aquaporins passively transport water out of cells IEA Plasmodium falciparum 15377 R-PFA-5221130 https://reactome.org/PathwayBrowser/#/R-PFA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Plasmodium falciparum 15377 R-PFA-5251959 https://reactome.org/PathwayBrowser/#/R-PFA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Plasmodium falciparum 15377 R-PFA-5251989 https://reactome.org/PathwayBrowser/#/R-PFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Plasmodium falciparum 15377 R-PFA-5263614 https://reactome.org/PathwayBrowser/#/R-PFA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Plasmodium falciparum 15377 R-PFA-5263616 https://reactome.org/PathwayBrowser/#/R-PFA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Plasmodium falciparum 15377 R-PFA-5607735 https://reactome.org/PathwayBrowser/#/R-PFA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Plasmodium falciparum 15377 R-PFA-5653786 https://reactome.org/PathwayBrowser/#/R-PFA-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Plasmodium falciparum 15377 R-PFA-5675373 https://reactome.org/PathwayBrowser/#/R-PFA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Plasmodium falciparum 15377 R-PFA-5675376 https://reactome.org/PathwayBrowser/#/R-PFA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Plasmodium falciparum 15377 R-PFA-5675433 https://reactome.org/PathwayBrowser/#/R-PFA-5675433 PP5 dephosphorylates RAF1 S338 IEA Plasmodium falciparum 15377 R-PFA-5676637 https://reactome.org/PathwayBrowser/#/R-PFA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Plasmodium falciparum 15377 R-PFA-5678706 https://reactome.org/PathwayBrowser/#/R-PFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Plasmodium falciparum 15377 R-PFA-5678863 https://reactome.org/PathwayBrowser/#/R-PFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-PFA-5682285 https://reactome.org/PathwayBrowser/#/R-PFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-PFA-5683714 https://reactome.org/PathwayBrowser/#/R-PFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Plasmodium falciparum 15377 R-PFA-5688797 https://reactome.org/PathwayBrowser/#/R-PFA-5688797 ATXN3 family cleave Ub chains IEA Plasmodium falciparum 15377 R-PFA-5688837 https://reactome.org/PathwayBrowser/#/R-PFA-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Plasmodium falciparum 15377 R-PFA-5690066 https://reactome.org/PathwayBrowser/#/R-PFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Plasmodium falciparum 15377 R-PFA-5690319 https://reactome.org/PathwayBrowser/#/R-PFA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Plasmodium falciparum 15377 R-PFA-5690565 https://reactome.org/PathwayBrowser/#/R-PFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15377 R-PFA-5690808 https://reactome.org/PathwayBrowser/#/R-PFA-5690808 UCHL3, SENP8 cleave NEDD8 IEA Plasmodium falciparum 15377 R-PFA-5691512 https://reactome.org/PathwayBrowser/#/R-PFA-5691512 APEH hydrolyses NAc-Ser-protein IEA Plasmodium falciparum 15377 R-PFA-5692462 https://reactome.org/PathwayBrowser/#/R-PFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Plasmodium falciparum 15377 R-PFA-5692480 https://reactome.org/PathwayBrowser/#/R-PFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Plasmodium falciparum 15377 R-PFA-5694137 https://reactome.org/PathwayBrowser/#/R-PFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Plasmodium falciparum 15377 R-PFA-5696197 https://reactome.org/PathwayBrowser/#/R-PFA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Plasmodium falciparum 15377 R-PFA-5696627 https://reactome.org/PathwayBrowser/#/R-PFA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Plasmodium falciparum 15377 R-PFA-6783221 https://reactome.org/PathwayBrowser/#/R-PFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Plasmodium falciparum 15377 R-PFA-6786421 https://reactome.org/PathwayBrowser/#/R-PFA-6786421 CHIA hydrolyses chitin IEA Plasmodium falciparum 15377 R-PFA-6786650 https://reactome.org/PathwayBrowser/#/R-PFA-6786650 DDHD1,2 hydrolyse PA IEA Plasmodium falciparum 15377 R-PFA-6786652 https://reactome.org/PathwayBrowser/#/R-PFA-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Plasmodium falciparum 15377 R-PFA-6787632 https://reactome.org/PathwayBrowser/#/R-PFA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Plasmodium falciparum 15377 R-PFA-6789310 https://reactome.org/PathwayBrowser/#/R-PFA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Plasmodium falciparum 15377 R-PFA-6801462 https://reactome.org/PathwayBrowser/#/R-PFA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Plasmodium falciparum 15377 R-PFA-70494 https://reactome.org/PathwayBrowser/#/R-PFA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Plasmodium falciparum 15377 R-PFA-70569 https://reactome.org/PathwayBrowser/#/R-PFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Plasmodium falciparum 15377 R-PFA-70599 https://reactome.org/PathwayBrowser/#/R-PFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Plasmodium falciparum 15377 R-PFA-70785 https://reactome.org/PathwayBrowser/#/R-PFA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Plasmodium falciparum 15377 R-PFA-70881 https://reactome.org/PathwayBrowser/#/R-PFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Plasmodium falciparum 15377 R-PFA-70975 https://reactome.org/PathwayBrowser/#/R-PFA-70975 CS acetylates OA to citrate IEA Plasmodium falciparum 15377 R-PFA-71146 https://reactome.org/PathwayBrowser/#/R-PFA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Plasmodium falciparum 15377 R-PFA-71660 https://reactome.org/PathwayBrowser/#/R-PFA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Plasmodium falciparum 15377 R-PFA-71732 https://reactome.org/PathwayBrowser/#/R-PFA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Plasmodium falciparum 15377 R-PFA-73571 https://reactome.org/PathwayBrowser/#/R-PFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Plasmodium falciparum 15377 R-PFA-73577 https://reactome.org/PathwayBrowser/#/R-PFA-73577 CAD hexamer transforms L-Gln to CAP IEA Plasmodium falciparum 15377 R-PFA-73647 https://reactome.org/PathwayBrowser/#/R-PFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Plasmodium falciparum 15377 R-PFA-73666 https://reactome.org/PathwayBrowser/#/R-PFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Plasmodium falciparum 15377 R-PFA-73792 https://reactome.org/PathwayBrowser/#/R-PFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Plasmodium falciparum 15377 R-PFA-73794 https://reactome.org/PathwayBrowser/#/R-PFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Plasmodium falciparum 15377 R-PFA-74241 https://reactome.org/PathwayBrowser/#/R-PFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Plasmodium falciparum 15377 R-PFA-75899 https://reactome.org/PathwayBrowser/#/R-PFA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Plasmodium falciparum 15377 R-PFA-76590 https://reactome.org/PathwayBrowser/#/R-PFA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Plasmodium falciparum 15377 R-PFA-8847579 https://reactome.org/PathwayBrowser/#/R-PFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15377 R-PFA-8848053 https://reactome.org/PathwayBrowser/#/R-PFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Plasmodium falciparum 15377 R-PFA-8848215 https://reactome.org/PathwayBrowser/#/R-PFA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Plasmodium falciparum 15377 R-PFA-8848338 https://reactome.org/PathwayBrowser/#/R-PFA-8848338 PNPLA4 hydrolyzes TAG IEA Plasmodium falciparum 15377 R-PFA-8848339 https://reactome.org/PathwayBrowser/#/R-PFA-8848339 PNPLA5 hydrolyzes TAG IEA Plasmodium falciparum 15377 R-PFA-8848355 https://reactome.org/PathwayBrowser/#/R-PFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Plasmodium falciparum 15377 R-PFA-8849969 https://reactome.org/PathwayBrowser/#/R-PFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Plasmodium falciparum 15377 R-PFA-8850846 https://reactome.org/PathwayBrowser/#/R-PFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15377 R-PFA-8850854 https://reactome.org/PathwayBrowser/#/R-PFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15377 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15377 R-PFA-8851110 https://reactome.org/PathwayBrowser/#/R-PFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15377 R-PFA-8851129 https://reactome.org/PathwayBrowser/#/R-PFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15377 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15377 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15377 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15377 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15377 R-PFA-8854255 https://reactome.org/PathwayBrowser/#/R-PFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 15377 R-PFA-8854329 https://reactome.org/PathwayBrowser/#/R-PFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 15377 R-PFA-8866405 https://reactome.org/PathwayBrowser/#/R-PFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 15377 R-PFA-8866601 https://reactome.org/PathwayBrowser/#/R-PFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Plasmodium falciparum 15377 R-PFA-8959510 https://reactome.org/PathwayBrowser/#/R-PFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Plasmodium falciparum 15377 R-PFA-8979996 https://reactome.org/PathwayBrowser/#/R-PFA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Plasmodium falciparum 15377 R-PFA-9018868 https://reactome.org/PathwayBrowser/#/R-PFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Plasmodium falciparum 15377 R-PFA-9018895 https://reactome.org/PathwayBrowser/#/R-PFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Plasmodium falciparum 15377 R-PFA-9020271 https://reactome.org/PathwayBrowser/#/R-PFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Plasmodium falciparum 15377 R-PFA-9020273 https://reactome.org/PathwayBrowser/#/R-PFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Plasmodium falciparum 15377 R-PFA-917841 https://reactome.org/PathwayBrowser/#/R-PFA-917841 Acidification of Tf:TfR1 containing endosome IEA Plasmodium falciparum 15377 R-PFA-917979 https://reactome.org/PathwayBrowser/#/R-PFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-PFA-936883 https://reactome.org/PathwayBrowser/#/R-PFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Plasmodium falciparum 15377 R-PFA-936895 https://reactome.org/PathwayBrowser/#/R-PFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Plasmodium falciparum 15377 R-PFA-939763 https://reactome.org/PathwayBrowser/#/R-PFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-947591 https://reactome.org/PathwayBrowser/#/R-PFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Plasmodium falciparum 15377 R-PFA-9629675 https://reactome.org/PathwayBrowser/#/R-PFA-9629675 PDE3A hydrolyses cAMP to AMP IEA Plasmodium falciparum 15377 R-PFA-9644869 https://reactome.org/PathwayBrowser/#/R-PFA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Plasmodium falciparum 15377 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 15377 R-PFA-9661417 https://reactome.org/PathwayBrowser/#/R-PFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-PFA-9705507 https://reactome.org/PathwayBrowser/#/R-PFA-9705507 PDE3B hydrolyses cAMP to AMP IEA Plasmodium falciparum 15377 R-PFA-9708261 https://reactome.org/PathwayBrowser/#/R-PFA-9708261 PDE4A hydrolyses cAMP to AMP IEA Plasmodium falciparum 15377 R-PFA-9731228 https://reactome.org/PathwayBrowser/#/R-PFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Plasmodium falciparum 15377 R-PFA-9731590 https://reactome.org/PathwayBrowser/#/R-PFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Plasmodium falciparum 15377 R-PFA-9731613 https://reactome.org/PathwayBrowser/#/R-PFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Plasmodium falciparum 15377 R-PFA-9731632 https://reactome.org/PathwayBrowser/#/R-PFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Plasmodium falciparum 15377 R-PFA-9748945 https://reactome.org/PathwayBrowser/#/R-PFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Plasmodium falciparum 15377 R-PFA-9748957 https://reactome.org/PathwayBrowser/#/R-PFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Plasmodium falciparum 15377 R-PFA-9750546 https://reactome.org/PathwayBrowser/#/R-PFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-PFA-9753278 https://reactome.org/PathwayBrowser/#/R-PFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 15377 R-PFA-9753280 https://reactome.org/PathwayBrowser/#/R-PFA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Plasmodium falciparum 15377 R-PFA-9753283 https://reactome.org/PathwayBrowser/#/R-PFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 15377 R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-PFA-9754964 https://reactome.org/PathwayBrowser/#/R-PFA-9754964 ADA deamidates RBV IEA Plasmodium falciparum 15377 R-PFA-9755030 https://reactome.org/PathwayBrowser/#/R-PFA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Plasmodium falciparum 15377 R-PFA-9759454 https://reactome.org/PathwayBrowser/#/R-PFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Plasmodium falciparum 15377 R-PFA-9759461 https://reactome.org/PathwayBrowser/#/R-PFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Plasmodium falciparum 15377 R-PFA-9794120 https://reactome.org/PathwayBrowser/#/R-PFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Plasmodium falciparum 15377 R-PFA-9794572 https://reactome.org/PathwayBrowser/#/R-PFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Plasmodium falciparum 15377 R-PFA-9837419 https://reactome.org/PathwayBrowser/#/R-PFA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Plasmodium falciparum 15377 R-PFA-9839105 https://reactome.org/PathwayBrowser/#/R-PFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Plasmodium falciparum 15377 R-PFA-9843721 https://reactome.org/PathwayBrowser/#/R-PFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Plasmodium falciparum 15377 R-PFA-9853385 https://reactome.org/PathwayBrowser/#/R-PFA-9853385 PPP1CC dephosphorylates PLK1 IEA Plasmodium falciparum 15377 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 15377 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 15377 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 15377 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 15377 R-RNO-109415 https://reactome.org/PathwayBrowser/#/R-RNO-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Rattus norvegicus 15377 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 15377 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 15377 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 15377 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 15377 R-RNO-111742 https://reactome.org/PathwayBrowser/#/R-RNO-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 15377 R-RNO-111751 https://reactome.org/PathwayBrowser/#/R-RNO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 15377 R-RNO-111804 https://reactome.org/PathwayBrowser/#/R-RNO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 15377 R-RNO-111879 https://reactome.org/PathwayBrowser/#/R-RNO-111879 PIP2 hydrolysis IEA Rattus norvegicus 15377 R-RNO-111883 https://reactome.org/PathwayBrowser/#/R-RNO-111883 Hydrolysis of phosphatidylcholine IEA Rattus norvegicus 15377 R-RNO-111955 https://reactome.org/PathwayBrowser/#/R-RNO-111955 cAMP hydrolysis by Cam-PDE 1 IEA Rattus norvegicus 15377 R-RNO-111962 https://reactome.org/PathwayBrowser/#/R-RNO-111962 PDE4A,C,D hydrolyse cAMP IEA Rattus norvegicus 15377 R-RNO-112037 https://reactome.org/PathwayBrowser/#/R-RNO-112037 Inactivation of PLC beta IEA Rattus norvegicus 15377 R-RNO-113503 https://reactome.org/PathwayBrowser/#/R-RNO-113503 PP2A mediated localization of RB1 protein in chromatin IEA Rattus norvegicus 15377 R-RNO-1169192 https://reactome.org/PathwayBrowser/#/R-RNO-1169192 PTP1B dephosphorylates GHR IEA Rattus norvegicus 15377 R-RNO-1183128 https://reactome.org/PathwayBrowser/#/R-RNO-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Rattus norvegicus 15377 R-RNO-1237045 https://reactome.org/PathwayBrowser/#/R-RNO-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Rattus norvegicus 15377 R-RNO-1237047 https://reactome.org/PathwayBrowser/#/R-RNO-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Rattus norvegicus 15377 R-RNO-1237059 https://reactome.org/PathwayBrowser/#/R-RNO-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Rattus norvegicus 15377 R-RNO-1237081 https://reactome.org/PathwayBrowser/#/R-RNO-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Rattus norvegicus 15377 R-RNO-1237129 https://reactome.org/PathwayBrowser/#/R-RNO-1237129 Acireductone is created IEA Rattus norvegicus 15377 R-RNO-1247910 https://reactome.org/PathwayBrowser/#/R-RNO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Rattus norvegicus 15377 R-RNO-1247935 https://reactome.org/PathwayBrowser/#/R-RNO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Rattus norvegicus 15377 R-RNO-1363274 https://reactome.org/PathwayBrowser/#/R-RNO-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Rattus norvegicus 15377 R-RNO-1363276 https://reactome.org/PathwayBrowser/#/R-RNO-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Rattus norvegicus 15377 R-RNO-1369028 https://reactome.org/PathwayBrowser/#/R-RNO-1369028 ABCAs mediate lipid efflux IEA Rattus norvegicus 15377 R-RNO-1369052 https://reactome.org/PathwayBrowser/#/R-RNO-1369052 ABCAs mediate lipid influx IEA Rattus norvegicus 15377 R-RNO-1369065 https://reactome.org/PathwayBrowser/#/R-RNO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Rattus norvegicus 15377 R-RNO-139906 https://reactome.org/PathwayBrowser/#/R-RNO-139906 Activation of BAD by calcineurin IEA Rattus norvegicus 15377 R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 15377 R-RNO-140359 https://reactome.org/PathwayBrowser/#/R-RNO-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Rattus norvegicus 15377 R-RNO-141186 https://reactome.org/PathwayBrowser/#/R-RNO-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Rattus norvegicus 15377 R-RNO-141200 https://reactome.org/PathwayBrowser/#/R-RNO-141200 MAOB:FAD oxidatively deaminates of PEA IEA Rattus norvegicus 15377 R-RNO-141202 https://reactome.org/PathwayBrowser/#/R-RNO-141202 MAOB:FAD oxidatively deaminates TYR IEA Rattus norvegicus 15377 R-RNO-141341 https://reactome.org/PathwayBrowser/#/R-RNO-141341 SMOX-3 oxidises SPN to SPM IEA Rattus norvegicus 15377 R-RNO-141348 https://reactome.org/PathwayBrowser/#/R-RNO-141348 PAO:FAD oxidises NASPM to PTCN IEA Rattus norvegicus 15377 R-RNO-141351 https://reactome.org/PathwayBrowser/#/R-RNO-141351 PAOX:FAD oxidises NASPN to SPM IEA Rattus norvegicus 15377 R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 15377 R-RNO-1454916 https://reactome.org/PathwayBrowser/#/R-RNO-1454916 The ABCC family mediates organic anion transport IEA Rattus norvegicus 15377 R-RNO-1454928 https://reactome.org/PathwayBrowser/#/R-RNO-1454928 ABCG4 may mediate cholesterol efflux IEA Rattus norvegicus 15377 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 15377 R-RNO-1474146 https://reactome.org/PathwayBrowser/#/R-RNO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Rattus norvegicus 15377 R-RNO-1475017 https://reactome.org/PathwayBrowser/#/R-RNO-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Rattus norvegicus 15377 R-RNO-1475022 https://reactome.org/PathwayBrowser/#/R-RNO-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Rattus norvegicus 15377 R-RNO-1475025 https://reactome.org/PathwayBrowser/#/R-RNO-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Rattus norvegicus 15377 R-RNO-1475026 https://reactome.org/PathwayBrowser/#/R-RNO-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Rattus norvegicus 15377 R-RNO-1475028 https://reactome.org/PathwayBrowser/#/R-RNO-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Rattus norvegicus 15377 R-RNO-1475032 https://reactome.org/PathwayBrowser/#/R-RNO-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Rattus norvegicus 15377 R-RNO-1475435 https://reactome.org/PathwayBrowser/#/R-RNO-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Rattus norvegicus 15377 R-RNO-1475436 https://reactome.org/PathwayBrowser/#/R-RNO-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Rattus norvegicus 15377 R-RNO-1482543 https://reactome.org/PathwayBrowser/#/R-RNO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Rattus norvegicus 15377 R-RNO-1482545 https://reactome.org/PathwayBrowser/#/R-RNO-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Rattus norvegicus 15377 R-RNO-1482571 https://reactome.org/PathwayBrowser/#/R-RNO-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Rattus norvegicus 15377 R-RNO-1482604 https://reactome.org/PathwayBrowser/#/R-RNO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Rattus norvegicus 15377 R-RNO-1482612 https://reactome.org/PathwayBrowser/#/R-RNO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 15377 R-RNO-1482629 https://reactome.org/PathwayBrowser/#/R-RNO-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Rattus norvegicus 15377 R-RNO-1482656 https://reactome.org/PathwayBrowser/#/R-RNO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Rattus norvegicus 15377 R-RNO-1482679 https://reactome.org/PathwayBrowser/#/R-RNO-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Rattus norvegicus 15377 R-RNO-1482685 https://reactome.org/PathwayBrowser/#/R-RNO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 15377 R-RNO-1482696 https://reactome.org/PathwayBrowser/#/R-RNO-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Rattus norvegicus 15377 R-RNO-1482745 https://reactome.org/PathwayBrowser/#/R-RNO-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Rattus norvegicus 15377 R-RNO-1482759 https://reactome.org/PathwayBrowser/#/R-RNO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Rattus norvegicus 15377 R-RNO-1482771 https://reactome.org/PathwayBrowser/#/R-RNO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Rattus norvegicus 15377 R-RNO-1482776 https://reactome.org/PathwayBrowser/#/R-RNO-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Rattus norvegicus 15377 R-RNO-1482777 https://reactome.org/PathwayBrowser/#/R-RNO-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Rattus norvegicus 15377 R-RNO-1482811 https://reactome.org/PathwayBrowser/#/R-RNO-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Rattus norvegicus 15377 R-RNO-1482816 https://reactome.org/PathwayBrowser/#/R-RNO-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Rattus norvegicus 15377 R-RNO-1482825 https://reactome.org/PathwayBrowser/#/R-RNO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Rattus norvegicus 15377 R-RNO-1482827 https://reactome.org/PathwayBrowser/#/R-RNO-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Rattus norvegicus 15377 R-RNO-1482828 https://reactome.org/PathwayBrowser/#/R-RNO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Rattus norvegicus 15377 R-RNO-1482836 https://reactome.org/PathwayBrowser/#/R-RNO-1482836 CL is hydrolyzed to MLCL by Pla2g6 (IM) TAS Rattus norvegicus 15377 R-RNO-1482847 https://reactome.org/PathwayBrowser/#/R-RNO-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Rattus norvegicus 15377 R-RNO-1482856 https://reactome.org/PathwayBrowser/#/R-RNO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Rattus norvegicus 15377 R-RNO-1482862 https://reactome.org/PathwayBrowser/#/R-RNO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Rattus norvegicus 15377 R-RNO-1482868 https://reactome.org/PathwayBrowser/#/R-RNO-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Rattus norvegicus 15377 R-RNO-1482884 https://reactome.org/PathwayBrowser/#/R-RNO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Rattus norvegicus 15377 R-RNO-1482887 https://reactome.org/PathwayBrowser/#/R-RNO-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Rattus norvegicus 15377 R-RNO-1482892 https://reactome.org/PathwayBrowser/#/R-RNO-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Rattus norvegicus 15377 R-RNO-1482897 https://reactome.org/PathwayBrowser/#/R-RNO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Rattus norvegicus 15377 R-RNO-1482900 https://reactome.org/PathwayBrowser/#/R-RNO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Rattus norvegicus 15377 R-RNO-1482907 https://reactome.org/PathwayBrowser/#/R-RNO-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Rattus norvegicus 15377 R-RNO-1482920 https://reactome.org/PathwayBrowser/#/R-RNO-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Rattus norvegicus 15377 R-RNO-1482932 https://reactome.org/PathwayBrowser/#/R-RNO-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Rattus norvegicus 15377 R-RNO-1483096 https://reactome.org/PathwayBrowser/#/R-RNO-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Rattus norvegicus 15377 R-RNO-1483159 https://reactome.org/PathwayBrowser/#/R-RNO-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Rattus norvegicus 15377 R-RNO-1483182 https://reactome.org/PathwayBrowser/#/R-RNO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Rattus norvegicus 15377 R-RNO-1483203 https://reactome.org/PathwayBrowser/#/R-RNO-1483203 PA is dephosphorylated to DAG by LPIN IEA Rattus norvegicus 15377 R-RNO-156526 https://reactome.org/PathwayBrowser/#/R-RNO-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15377 R-RNO-159425 https://reactome.org/PathwayBrowser/#/R-RNO-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 15377 R-RNO-159752 https://reactome.org/PathwayBrowser/#/R-RNO-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Rattus norvegicus 15377 R-RNO-159761 https://reactome.org/PathwayBrowser/#/R-RNO-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Rattus norvegicus 15377 R-RNO-159795 https://reactome.org/PathwayBrowser/#/R-RNO-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Rattus norvegicus 15377 R-RNO-159803 https://reactome.org/PathwayBrowser/#/R-RNO-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Rattus norvegicus 15377 R-RNO-159819 https://reactome.org/PathwayBrowser/#/R-RNO-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Rattus norvegicus 15377 R-RNO-159826 https://reactome.org/PathwayBrowser/#/R-RNO-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Rattus norvegicus 15377 R-RNO-1602368 https://reactome.org/PathwayBrowser/#/R-RNO-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Rattus norvegicus 15377 R-RNO-1602374 https://reactome.org/PathwayBrowser/#/R-RNO-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Rattus norvegicus 15377 R-RNO-1602377 https://reactome.org/PathwayBrowser/#/R-RNO-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Rattus norvegicus 15377 R-RNO-1602398 https://reactome.org/PathwayBrowser/#/R-RNO-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Rattus norvegicus 15377 R-RNO-1602399 https://reactome.org/PathwayBrowser/#/R-RNO-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Rattus norvegicus 15377 R-RNO-1602417 https://reactome.org/PathwayBrowser/#/R-RNO-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Rattus norvegicus 15377 R-RNO-1602446 https://reactome.org/PathwayBrowser/#/R-RNO-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Rattus norvegicus 15377 R-RNO-1605591 https://reactome.org/PathwayBrowser/#/R-RNO-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Rattus norvegicus 15377 R-RNO-1605595 https://reactome.org/PathwayBrowser/#/R-RNO-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Rattus norvegicus 15377 R-RNO-1605624 https://reactome.org/PathwayBrowser/#/R-RNO-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Rattus norvegicus 15377 R-RNO-1605632 https://reactome.org/PathwayBrowser/#/R-RNO-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Rattus norvegicus 15377 R-RNO-1605723 https://reactome.org/PathwayBrowser/#/R-RNO-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Rattus norvegicus 15377 R-RNO-1605724 https://reactome.org/PathwayBrowser/#/R-RNO-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Rattus norvegicus 15377 R-RNO-1605736 https://reactome.org/PathwayBrowser/#/R-RNO-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Rattus norvegicus 15377 R-RNO-1605768 https://reactome.org/PathwayBrowser/#/R-RNO-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Rattus norvegicus 15377 R-RNO-1605797 https://reactome.org/PathwayBrowser/#/R-RNO-1605797 SMPD1 hydrolyzes SPHM IEA Rattus norvegicus 15377 R-RNO-1606273 https://reactome.org/PathwayBrowser/#/R-RNO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Rattus norvegicus 15377 R-RNO-1606288 https://reactome.org/PathwayBrowser/#/R-RNO-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Rattus norvegicus 15377 R-RNO-1606312 https://reactome.org/PathwayBrowser/#/R-RNO-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Rattus norvegicus 15377 R-RNO-1606564 https://reactome.org/PathwayBrowser/#/R-RNO-1606564 GALC hydrolyzes GalCer IEA Rattus norvegicus 15377 R-RNO-1606583 https://reactome.org/PathwayBrowser/#/R-RNO-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Rattus norvegicus 15377 R-RNO-1606602 https://reactome.org/PathwayBrowser/#/R-RNO-1606602 ASAH1 hydrolyzes ceramide IEA Rattus norvegicus 15377 R-RNO-1606789 https://reactome.org/PathwayBrowser/#/R-RNO-1606789 ARSB hydrolyses DS IEA Rattus norvegicus 15377 R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 15377 R-RNO-1606839 https://reactome.org/PathwayBrowser/#/R-RNO-1606839 ARSC hydrolyzes steroid sulfates IEA Rattus norvegicus 15377 R-RNO-1614524 https://reactome.org/PathwayBrowser/#/R-RNO-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Rattus norvegicus 15377 R-RNO-1614544 https://reactome.org/PathwayBrowser/#/R-RNO-1614544 Sulfite is oxidized to sulfate IEA Rattus norvegicus 15377 R-RNO-1614583 https://reactome.org/PathwayBrowser/#/R-RNO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Rattus norvegicus 15377 R-RNO-1614605 https://reactome.org/PathwayBrowser/#/R-RNO-1614605 Persulfide sulfur is dioxygenated IEA Rattus norvegicus 15377 R-RNO-1614614 https://reactome.org/PathwayBrowser/#/R-RNO-1614614 Cysteine is degraded to serine and H2S IEA Rattus norvegicus 15377 R-RNO-1614631 https://reactome.org/PathwayBrowser/#/R-RNO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Rattus norvegicus 15377 R-RNO-162425 https://reactome.org/PathwayBrowser/#/R-RNO-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Rattus norvegicus 15377 R-RNO-162729 https://reactome.org/PathwayBrowser/#/R-RNO-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Rattus norvegicus 15377 R-RNO-162857 https://reactome.org/PathwayBrowser/#/R-RNO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Rattus norvegicus 15377 R-RNO-1630304 https://reactome.org/PathwayBrowser/#/R-RNO-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Rattus norvegicus 15377 R-RNO-1630306 https://reactome.org/PathwayBrowser/#/R-RNO-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Rattus norvegicus 15377 R-RNO-163120 https://reactome.org/PathwayBrowser/#/R-RNO-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Rattus norvegicus 15377 R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 15377 R-RNO-163398 https://reactome.org/PathwayBrowser/#/R-RNO-163398 phosphorylated HSL + H2O -> HSL + orthophosphate TAS Rattus norvegicus 15377 R-RNO-163407 https://reactome.org/PathwayBrowser/#/R-RNO-163407 cholesterol ester + H2O -> cholesterol + fatty acid TAS Rattus norvegicus 15377 R-RNO-163439 https://reactome.org/PathwayBrowser/#/R-RNO-163439 2-acylglycerol + H2O -> glycerol + fatty acid TAS Rattus norvegicus 15377 R-RNO-163440 https://reactome.org/PathwayBrowser/#/R-RNO-163440 diacylglycerol + H2O -> 2-acylglycerol + fatty acid TAS Rattus norvegicus 15377 R-RNO-163515 https://reactome.org/PathwayBrowser/#/R-RNO-163515 triacylglycerol + H2O -> diacylglycerol + fatty acid TAS Rattus norvegicus 15377 R-RNO-163609 https://reactome.org/PathwayBrowser/#/R-RNO-163609 phosphorylated perilipin + H2O -> perilipin + orthophosphate TAS Rattus norvegicus 15377 R-RNO-1638032 https://reactome.org/PathwayBrowser/#/R-RNO-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Rattus norvegicus 15377 R-RNO-1638053 https://reactome.org/PathwayBrowser/#/R-RNO-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Rattus norvegicus 15377 R-RNO-163820 https://reactome.org/PathwayBrowser/#/R-RNO-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Rattus norvegicus 15377 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus 15377 R-RNO-1640164 https://reactome.org/PathwayBrowser/#/R-RNO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Rattus norvegicus 15377 R-RNO-164832 https://reactome.org/PathwayBrowser/#/R-RNO-164832 ATPase synthesizes ATP IEA Rattus norvegicus 15377 R-RNO-1655453 https://reactome.org/PathwayBrowser/#/R-RNO-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Rattus norvegicus 15377 R-RNO-1667005 https://reactome.org/PathwayBrowser/#/R-RNO-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Rattus norvegicus 15377 R-RNO-1675795 https://reactome.org/PathwayBrowser/#/R-RNO-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Rattus norvegicus 15377 R-RNO-1675824 https://reactome.org/PathwayBrowser/#/R-RNO-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Rattus norvegicus 15377 R-RNO-1675836 https://reactome.org/PathwayBrowser/#/R-RNO-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1675949 https://reactome.org/PathwayBrowser/#/R-RNO-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1675988 https://reactome.org/PathwayBrowser/#/R-RNO-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1675994 https://reactome.org/PathwayBrowser/#/R-RNO-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1676005 https://reactome.org/PathwayBrowser/#/R-RNO-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Rattus norvegicus 15377 R-RNO-1676020 https://reactome.org/PathwayBrowser/#/R-RNO-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Rattus norvegicus 15377 R-RNO-1676065 https://reactome.org/PathwayBrowser/#/R-RNO-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Rattus norvegicus 15377 R-RNO-1676105 https://reactome.org/PathwayBrowser/#/R-RNO-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Rattus norvegicus 15377 R-RNO-1676114 https://reactome.org/PathwayBrowser/#/R-RNO-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Rattus norvegicus 15377 R-RNO-1676124 https://reactome.org/PathwayBrowser/#/R-RNO-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Rattus norvegicus 15377 R-RNO-1676141 https://reactome.org/PathwayBrowser/#/R-RNO-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Rattus norvegicus 15377 R-RNO-1676149 https://reactome.org/PathwayBrowser/#/R-RNO-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1676162 https://reactome.org/PathwayBrowser/#/R-RNO-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Rattus norvegicus 15377 R-RNO-1676164 https://reactome.org/PathwayBrowser/#/R-RNO-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1676174 https://reactome.org/PathwayBrowser/#/R-RNO-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Rattus norvegicus 15377 R-RNO-1676177 https://reactome.org/PathwayBrowser/#/R-RNO-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1676203 https://reactome.org/PathwayBrowser/#/R-RNO-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1676204 https://reactome.org/PathwayBrowser/#/R-RNO-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Rattus norvegicus 15377 R-RNO-1678650 https://reactome.org/PathwayBrowser/#/R-RNO-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Rattus norvegicus 15377 R-RNO-1678708 https://reactome.org/PathwayBrowser/#/R-RNO-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Rattus norvegicus 15377 R-RNO-1678716 https://reactome.org/PathwayBrowser/#/R-RNO-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Rattus norvegicus 15377 R-RNO-1678742 https://reactome.org/PathwayBrowser/#/R-RNO-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Rattus norvegicus 15377 R-RNO-1678854 https://reactome.org/PathwayBrowser/#/R-RNO-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Rattus norvegicus 15377 R-RNO-170153 https://reactome.org/PathwayBrowser/#/R-RNO-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Rattus norvegicus 15377 R-RNO-170158 https://reactome.org/PathwayBrowser/#/R-RNO-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Rattus norvegicus 15377 R-RNO-170161 https://reactome.org/PathwayBrowser/#/R-RNO-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Rattus norvegicus 15377 R-RNO-173597 https://reactome.org/PathwayBrowser/#/R-RNO-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Rattus norvegicus 15377 R-RNO-173739 https://reactome.org/PathwayBrowser/#/R-RNO-173739 Spontaneous hydrolysis of C3 thioester IEA Rattus norvegicus 15377 R-RNO-174110 https://reactome.org/PathwayBrowser/#/R-RNO-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Rattus norvegicus 15377 R-RNO-174124 https://reactome.org/PathwayBrowser/#/R-RNO-174124 Dephosphorylation of phospho-Cdh1 IEA Rattus norvegicus 15377 R-RNO-174391 https://reactome.org/PathwayBrowser/#/R-RNO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Rattus norvegicus 15377 R-RNO-174401 https://reactome.org/PathwayBrowser/#/R-RNO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Rattus norvegicus 15377 R-RNO-174438 https://reactome.org/PathwayBrowser/#/R-RNO-174438 Formation of the Flap Intermediate on the C-strand IEA Rattus norvegicus 15377 R-RNO-174439 https://reactome.org/PathwayBrowser/#/R-RNO-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Rattus norvegicus 15377 R-RNO-176606 https://reactome.org/PathwayBrowser/#/R-RNO-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Rattus norvegicus 15377 R-RNO-177923 https://reactome.org/PathwayBrowser/#/R-RNO-177923 Sustained activation of SRC kinase by SHP2 IEA Rattus norvegicus 15377 R-RNO-177924 https://reactome.org/PathwayBrowser/#/R-RNO-177924 Dephosphorylation of Gab1 by SHP2 IEA Rattus norvegicus 15377 R-RNO-177926 https://reactome.org/PathwayBrowser/#/R-RNO-177926 Dephosphorylation of PAG by SHP2 IEA Rattus norvegicus 15377 R-RNO-177935 https://reactome.org/PathwayBrowser/#/R-RNO-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Rattus norvegicus 15377 R-RNO-1793182 https://reactome.org/PathwayBrowser/#/R-RNO-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Rattus norvegicus 15377 R-RNO-1793186 https://reactome.org/PathwayBrowser/#/R-RNO-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Rattus norvegicus 15377 R-RNO-1793207 https://reactome.org/PathwayBrowser/#/R-RNO-1793207 ARSB hydrolyses C4S/C6S chains IEA Rattus norvegicus 15377 R-RNO-1793209 https://reactome.org/PathwayBrowser/#/R-RNO-1793209 HYAL1 hydrolyses Chondroitin chains IEA Rattus norvegicus 15377 R-RNO-182041 https://reactome.org/PathwayBrowser/#/R-RNO-182041 Endocytosis of clathrin-coated vesicle TAS Rattus norvegicus 15377 R-RNO-182061 https://reactome.org/PathwayBrowser/#/R-RNO-182061 Active Plcg1 hydrolyses PIP2 TAS Rattus norvegicus 15377 R-RNO-1855154 https://reactome.org/PathwayBrowser/#/R-RNO-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855159 https://reactome.org/PathwayBrowser/#/R-RNO-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855163 https://reactome.org/PathwayBrowser/#/R-RNO-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Rattus norvegicus 15377 R-RNO-1855165 https://reactome.org/PathwayBrowser/#/R-RNO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855166 https://reactome.org/PathwayBrowser/#/R-RNO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855171 https://reactome.org/PathwayBrowser/#/R-RNO-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855174 https://reactome.org/PathwayBrowser/#/R-RNO-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855177 https://reactome.org/PathwayBrowser/#/R-RNO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1855180 https://reactome.org/PathwayBrowser/#/R-RNO-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855198 https://reactome.org/PathwayBrowser/#/R-RNO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855200 https://reactome.org/PathwayBrowser/#/R-RNO-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Rattus norvegicus 15377 R-RNO-1855202 https://reactome.org/PathwayBrowser/#/R-RNO-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855205 https://reactome.org/PathwayBrowser/#/R-RNO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855208 https://reactome.org/PathwayBrowser/#/R-RNO-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855210 https://reactome.org/PathwayBrowser/#/R-RNO-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855211 https://reactome.org/PathwayBrowser/#/R-RNO-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855213 https://reactome.org/PathwayBrowser/#/R-RNO-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1855214 https://reactome.org/PathwayBrowser/#/R-RNO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Rattus norvegicus 15377 R-RNO-1855218 https://reactome.org/PathwayBrowser/#/R-RNO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855219 https://reactome.org/PathwayBrowser/#/R-RNO-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 15377 R-RNO-1855221 https://reactome.org/PathwayBrowser/#/R-RNO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1855222 https://reactome.org/PathwayBrowser/#/R-RNO-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-1855225 https://reactome.org/PathwayBrowser/#/R-RNO-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Rattus norvegicus 15377 R-RNO-1855232 https://reactome.org/PathwayBrowser/#/R-RNO-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Rattus norvegicus 15377 R-RNO-1861788 https://reactome.org/PathwayBrowser/#/R-RNO-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Rattus norvegicus 15377 R-RNO-1861789 https://reactome.org/PathwayBrowser/#/R-RNO-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Rattus norvegicus 15377 R-RNO-188979 https://reactome.org/PathwayBrowser/#/R-RNO-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Rattus norvegicus 15377 R-RNO-189053 https://reactome.org/PathwayBrowser/#/R-RNO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Rattus norvegicus 15377 R-RNO-189062 https://reactome.org/PathwayBrowser/#/R-RNO-189062 lactose + H2O => D-glucose + D-galactose IEA Rattus norvegicus 15377 R-RNO-189069 https://reactome.org/PathwayBrowser/#/R-RNO-189069 sucrose + H2O => glucose + fructose IEA Rattus norvegicus 15377 R-RNO-189398 https://reactome.org/PathwayBrowser/#/R-RNO-189398 HMOX1 dimer, HMOX2 cleave heme IEA Rattus norvegicus 15377 R-RNO-189406 https://reactome.org/PathwayBrowser/#/R-RNO-189406 4 PBGs bind to form HMB IEA Rattus norvegicus 15377 R-RNO-189421 https://reactome.org/PathwayBrowser/#/R-RNO-189421 CPO transforms COPRO3 to PPGEN9 IEA Rattus norvegicus 15377 R-RNO-189439 https://reactome.org/PathwayBrowser/#/R-RNO-189439 ALAD condenses 2 dALAs to form PBG IEA Rattus norvegicus 15377 R-RNO-189488 https://reactome.org/PathwayBrowser/#/R-RNO-189488 UROS transforms HMB to URO3 IEA Rattus norvegicus 15377 R-RNO-191101 https://reactome.org/PathwayBrowser/#/R-RNO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 15377 R-RNO-191108 https://reactome.org/PathwayBrowser/#/R-RNO-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 15377 R-RNO-191114 https://reactome.org/PathwayBrowser/#/R-RNO-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Rattus norvegicus 15377 R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 15377 R-RNO-191323 https://reactome.org/PathwayBrowser/#/R-RNO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Rattus norvegicus 15377 R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 15377 R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 15377 R-RNO-191999 https://reactome.org/PathwayBrowser/#/R-RNO-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Rattus norvegicus 15377 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 15377 R-RNO-192054 https://reactome.org/PathwayBrowser/#/R-RNO-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Rattus norvegicus 15377 R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 15377 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 15377 R-RNO-192123 https://reactome.org/PathwayBrowser/#/R-RNO-192123 CYP27A1 27-hydroxylates CHOL IEA Rattus norvegicus 15377 R-RNO-192157 https://reactome.org/PathwayBrowser/#/R-RNO-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Rattus norvegicus 15377 R-RNO-192178 https://reactome.org/PathwayBrowser/#/R-RNO-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Rattus norvegicus 15377 R-RNO-192331 https://reactome.org/PathwayBrowser/#/R-RNO-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 15377 R-RNO-192422 https://reactome.org/PathwayBrowser/#/R-RNO-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Rattus norvegicus 15377 R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 15377 R-RNO-192430 https://reactome.org/PathwayBrowser/#/R-RNO-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 15377 R-RNO-192434 https://reactome.org/PathwayBrowser/#/R-RNO-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Rattus norvegicus 15377 R-RNO-192475 https://reactome.org/PathwayBrowser/#/R-RNO-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Rattus norvegicus 15377 R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 15377 R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 15377 R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 15377 R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 15377 R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 15377 R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 15377 R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 15377 R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 15377 R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 15377 R-RNO-193362 https://reactome.org/PathwayBrowser/#/R-RNO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 15377 R-RNO-193385 https://reactome.org/PathwayBrowser/#/R-RNO-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Rattus norvegicus 15377 R-RNO-193393 https://reactome.org/PathwayBrowser/#/R-RNO-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Rattus norvegicus 15377 R-RNO-193460 https://reactome.org/PathwayBrowser/#/R-RNO-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Rattus norvegicus 15377 R-RNO-193535 https://reactome.org/PathwayBrowser/#/R-RNO-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-193709 https://reactome.org/PathwayBrowser/#/R-RNO-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Rattus norvegicus 15377 R-RNO-193711 https://reactome.org/PathwayBrowser/#/R-RNO-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 15377 R-RNO-193713 https://reactome.org/PathwayBrowser/#/R-RNO-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Rattus norvegicus 15377 R-RNO-193719 https://reactome.org/PathwayBrowser/#/R-RNO-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15377 R-RNO-193727 https://reactome.org/PathwayBrowser/#/R-RNO-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 15377 R-RNO-193737 https://reactome.org/PathwayBrowser/#/R-RNO-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Rattus norvegicus 15377 R-RNO-193743 https://reactome.org/PathwayBrowser/#/R-RNO-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 15377 R-RNO-193766 https://reactome.org/PathwayBrowser/#/R-RNO-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 15377 R-RNO-193780 https://reactome.org/PathwayBrowser/#/R-RNO-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15377 R-RNO-193787 https://reactome.org/PathwayBrowser/#/R-RNO-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Rattus norvegicus 15377 R-RNO-193792 https://reactome.org/PathwayBrowser/#/R-RNO-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Rattus norvegicus 15377 R-RNO-193845 https://reactome.org/PathwayBrowser/#/R-RNO-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Rattus norvegicus 15377 R-RNO-193964 https://reactome.org/PathwayBrowser/#/R-RNO-193964 CYP21A2 21-hydroxylates PROG IEA Rattus norvegicus 15377 R-RNO-193965 https://reactome.org/PathwayBrowser/#/R-RNO-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Rattus norvegicus 15377 R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 15377 R-RNO-193995 https://reactome.org/PathwayBrowser/#/R-RNO-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Rattus norvegicus 15377 R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 15377 R-RNO-194017 https://reactome.org/PathwayBrowser/#/R-RNO-194017 CYP11B2 oxidises 11DCORST to CORST IEA Rattus norvegicus 15377 R-RNO-194641 https://reactome.org/PathwayBrowser/#/R-RNO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15377 R-RNO-194669 https://reactome.org/PathwayBrowser/#/R-RNO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15377 R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 15377 R-RNO-195664 https://reactome.org/PathwayBrowser/#/R-RNO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Rattus norvegicus 15377 R-RNO-196950 https://reactome.org/PathwayBrowser/#/R-RNO-196950 2xTRAP hydrolyzes FMN to RIB IEA Rattus norvegicus 15377 R-RNO-196955 https://reactome.org/PathwayBrowser/#/R-RNO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Rattus norvegicus 15377 R-RNO-197271 https://reactome.org/PathwayBrowser/#/R-RNO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Rattus norvegicus 15377 R-RNO-199425 https://reactome.org/PathwayBrowser/#/R-RNO-199425 PHLPP dephosphorylates S473 in AKT IEA Rattus norvegicus 15377 R-RNO-199456 https://reactome.org/PathwayBrowser/#/R-RNO-199456 PTEN dephosphorylates PIP3 IEA Rattus norvegicus 15377 R-RNO-199959 https://reactome.org/PathwayBrowser/#/R-RNO-199959 ERKs are inactivated by protein phosphatase 2A IEA Rattus norvegicus 15377 R-RNO-2002466 https://reactome.org/PathwayBrowser/#/R-RNO-2002466 Formation of allysine by LOX IEA Rattus norvegicus 15377 R-RNO-200661 https://reactome.org/PathwayBrowser/#/R-RNO-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Rattus norvegicus 15377 R-RNO-200740 https://reactome.org/PathwayBrowser/#/R-RNO-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Rattus norvegicus 15377 R-RNO-201035 https://reactome.org/PathwayBrowser/#/R-RNO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Rattus norvegicus 15377 R-RNO-201760 https://reactome.org/PathwayBrowser/#/R-RNO-201760 Ppp3 complex dephosphorylates DARPP-32 on T34 TAS Rattus norvegicus 15377 R-RNO-201790 https://reactome.org/PathwayBrowser/#/R-RNO-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Rattus norvegicus 15377 R-RNO-202214 https://reactome.org/PathwayBrowser/#/R-RNO-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Rattus norvegicus 15377 R-RNO-2022368 https://reactome.org/PathwayBrowser/#/R-RNO-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Rattus norvegicus 15377 R-RNO-202237 https://reactome.org/PathwayBrowser/#/R-RNO-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Rattus norvegicus 15377 R-RNO-2022378 https://reactome.org/PathwayBrowser/#/R-RNO-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Rattus norvegicus 15377 R-RNO-2022379 https://reactome.org/PathwayBrowser/#/R-RNO-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Rattus norvegicus 15377 R-RNO-2022381 https://reactome.org/PathwayBrowser/#/R-RNO-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 15377 R-RNO-2022383 https://reactome.org/PathwayBrowser/#/R-RNO-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 15377 R-RNO-2022396 https://reactome.org/PathwayBrowser/#/R-RNO-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Rattus norvegicus 15377 R-RNO-2022398 https://reactome.org/PathwayBrowser/#/R-RNO-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Rattus norvegicus 15377 R-RNO-2022399 https://reactome.org/PathwayBrowser/#/R-RNO-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Rattus norvegicus 15377 R-RNO-2022403 https://reactome.org/PathwayBrowser/#/R-RNO-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Rattus norvegicus 15377 R-RNO-2022405 https://reactome.org/PathwayBrowser/#/R-RNO-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 15377 R-RNO-2022411 https://reactome.org/PathwayBrowser/#/R-RNO-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 15377 R-RNO-2022412 https://reactome.org/PathwayBrowser/#/R-RNO-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Rattus norvegicus 15377 R-RNO-2022887 https://reactome.org/PathwayBrowser/#/R-RNO-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Rattus norvegicus 15377 R-RNO-2023971 https://reactome.org/PathwayBrowser/#/R-RNO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 15377 R-RNO-2023973 https://reactome.org/PathwayBrowser/#/R-RNO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 15377 R-RNO-202407 https://reactome.org/PathwayBrowser/#/R-RNO-202407 PLC-gamma1 hydrolyses PIP2 IEA Rattus norvegicus 15377 R-RNO-2028294 https://reactome.org/PathwayBrowser/#/R-RNO-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Rattus norvegicus 15377 R-RNO-2029468 https://reactome.org/PathwayBrowser/#/R-RNO-2029468 Conversion of PA into DAG by PAP-1 IEA Rattus norvegicus 15377 R-RNO-2029471 https://reactome.org/PathwayBrowser/#/R-RNO-2029471 Hydrolysis of PC to PA by PLD IEA Rattus norvegicus 15377 R-RNO-2029475 https://reactome.org/PathwayBrowser/#/R-RNO-2029475 Production of AA by iPLA2 upon FCGR activation IEA Rattus norvegicus 15377 R-RNO-203797 https://reactome.org/PathwayBrowser/#/R-RNO-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Rattus norvegicus 15377 R-RNO-204169 https://reactome.org/PathwayBrowser/#/R-RNO-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Rattus norvegicus 15377 R-RNO-2046083 https://reactome.org/PathwayBrowser/#/R-RNO-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Rattus norvegicus 15377 R-RNO-2046084 https://reactome.org/PathwayBrowser/#/R-RNO-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Rattus norvegicus 15377 R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus 15377 R-RNO-2046089 https://reactome.org/PathwayBrowser/#/R-RNO-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Rattus norvegicus 15377 R-RNO-2046090 https://reactome.org/PathwayBrowser/#/R-RNO-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 15377 R-RNO-2046091 https://reactome.org/PathwayBrowser/#/R-RNO-2046091 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA TAS Rattus norvegicus 15377 R-RNO-2046092 https://reactome.org/PathwayBrowser/#/R-RNO-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Rattus norvegicus 15377 R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus 15377 R-RNO-2046095 https://reactome.org/PathwayBrowser/#/R-RNO-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Rattus norvegicus 15377 R-RNO-2046096 https://reactome.org/PathwayBrowser/#/R-RNO-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Rattus norvegicus 15377 R-RNO-2046097 https://reactome.org/PathwayBrowser/#/R-RNO-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 15377 R-RNO-2046100 https://reactome.org/PathwayBrowser/#/R-RNO-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Rattus norvegicus 15377 R-RNO-204662 https://reactome.org/PathwayBrowser/#/R-RNO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Rattus norvegicus 15377 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 15377 R-RNO-2065357 https://reactome.org/PathwayBrowser/#/R-RNO-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Rattus norvegicus 15377 R-RNO-2066778 https://reactome.org/PathwayBrowser/#/R-RNO-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Rattus norvegicus 15377 R-RNO-2066779 https://reactome.org/PathwayBrowser/#/R-RNO-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Rattus norvegicus 15377 R-RNO-2090037 https://reactome.org/PathwayBrowser/#/R-RNO-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Rattus norvegicus 15377 R-RNO-2090038 https://reactome.org/PathwayBrowser/#/R-RNO-2090038 NAGLU hydrolyses heparan chain(2) IEA Rattus norvegicus 15377 R-RNO-2090043 https://reactome.org/PathwayBrowser/#/R-RNO-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Rattus norvegicus 15377 R-RNO-2090079 https://reactome.org/PathwayBrowser/#/R-RNO-2090079 GLB1 hydrolyses linker chain(2) IEA Rattus norvegicus 15377 R-RNO-209055 https://reactome.org/PathwayBrowser/#/R-RNO-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Rattus norvegicus 15377 R-RNO-209562 https://reactome.org/PathwayBrowser/#/R-RNO-209562 Production of ceramide which can activate JNK and other targets TAS Rattus norvegicus 15377 R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 15377 R-RNO-209845 https://reactome.org/PathwayBrowser/#/R-RNO-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Rattus norvegicus 15377 R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 15377 R-RNO-209891 https://reactome.org/PathwayBrowser/#/R-RNO-209891 Dopamine is oxidised to noradrenaline IEA Rattus norvegicus 15377 R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 15377 R-RNO-2105001 https://reactome.org/PathwayBrowser/#/R-RNO-2105001 HEXA cleaves the terminal GalNAc from DS IEA Rattus norvegicus 15377 R-RNO-211873 https://reactome.org/PathwayBrowser/#/R-RNO-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Rattus norvegicus 15377 R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 15377 R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 15377 R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 15377 R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 15377 R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 15377 R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 15377 R-RNO-211923 https://reactome.org/PathwayBrowser/#/R-RNO-211923 CYP26C1 4-hydroxylates 9cRA IEA Rattus norvegicus 15377 R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 15377 R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 15377 R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 15377 R-RNO-211950 https://reactome.org/PathwayBrowser/#/R-RNO-211950 CYP24A1 24-hydroxylates CTL IEA Rattus norvegicus 15377 R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 15377 R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 15377 R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 15377 R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 15377 R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 15377 R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 15377 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 15377 R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 15377 R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 15377 R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 15377 R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 15377 R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 15377 R-RNO-2130725 https://reactome.org/PathwayBrowser/#/R-RNO-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Rattus norvegicus 15377 R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15377 R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 15377 R-RNO-2160492 https://reactome.org/PathwayBrowser/#/R-RNO-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Rattus norvegicus 15377 R-RNO-2160874 https://reactome.org/PathwayBrowser/#/R-RNO-2160874 HYAL1 hydrolyses (HA)50 IEA Rattus norvegicus 15377 R-RNO-2161745 https://reactome.org/PathwayBrowser/#/R-RNO-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15377 R-RNO-2161791 https://reactome.org/PathwayBrowser/#/R-RNO-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Rattus norvegicus 15377 R-RNO-2161792 https://reactome.org/PathwayBrowser/#/R-RNO-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15377 R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Rattus norvegicus 15377 R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 15377 R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus 15377 R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Rattus norvegicus 15377 R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 15377 R-RNO-2161951 https://reactome.org/PathwayBrowser/#/R-RNO-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Rattus norvegicus 15377 R-RNO-2161959 https://reactome.org/PathwayBrowser/#/R-RNO-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Rattus norvegicus 15377 R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Rattus norvegicus 15377 R-RNO-2161999 https://reactome.org/PathwayBrowser/#/R-RNO-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Rattus norvegicus 15377 R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 15377 R-RNO-2162225 https://reactome.org/PathwayBrowser/#/R-RNO-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Rattus norvegicus 15377 R-RNO-2162226 https://reactome.org/PathwayBrowser/#/R-RNO-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Rattus norvegicus 15377 R-RNO-2162227 https://reactome.org/PathwayBrowser/#/R-RNO-2162227 GUSB tetramer hydrolyses (HA)2 IEA Rattus norvegicus 15377 R-RNO-216723 https://reactome.org/PathwayBrowser/#/R-RNO-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 15377 R-RNO-216757 https://reactome.org/PathwayBrowser/#/R-RNO-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 15377 R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 15377 R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 15377 R-RNO-2187401 https://reactome.org/PathwayBrowser/#/R-RNO-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Rattus norvegicus 15377 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 15377 R-RNO-2393939 https://reactome.org/PathwayBrowser/#/R-RNO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 15377 R-RNO-2393954 https://reactome.org/PathwayBrowser/#/R-RNO-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 15377 R-RNO-2395340 https://reactome.org/PathwayBrowser/#/R-RNO-2395340 Formation of hydroxyallysine by LOX IEA Rattus norvegicus 15377 R-RNO-2395818 https://reactome.org/PathwayBrowser/#/R-RNO-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Rattus norvegicus 15377 R-RNO-2395849 https://reactome.org/PathwayBrowser/#/R-RNO-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 15377 R-RNO-2395869 https://reactome.org/PathwayBrowser/#/R-RNO-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 15377 R-RNO-2395872 https://reactome.org/PathwayBrowser/#/R-RNO-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Rattus norvegicus 15377 R-RNO-2395873 https://reactome.org/PathwayBrowser/#/R-RNO-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Rattus norvegicus 15377 R-RNO-2395876 https://reactome.org/PathwayBrowser/#/R-RNO-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 15377 R-RNO-2395879 https://reactome.org/PathwayBrowser/#/R-RNO-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 15377 R-RNO-2395965 https://reactome.org/PathwayBrowser/#/R-RNO-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Rattus norvegicus 15377 R-RNO-2408502 https://reactome.org/PathwayBrowser/#/R-RNO-2408502 SeCysta is hydrolysed to Sec by PXLP-K211-Cth TAS Rattus norvegicus 15377 R-RNO-2408512 https://reactome.org/PathwayBrowser/#/R-RNO-2408512 AdeSeHCys is hydrolysed to SeHCys by Ahcy TAS Rattus norvegicus 15377 R-RNO-2408521 https://reactome.org/PathwayBrowser/#/R-RNO-2408521 MeSeH is hydrolysed to H2Se by methylselenol demethylase TAS Rattus norvegicus 15377 R-RNO-2408533 https://reactome.org/PathwayBrowser/#/R-RNO-2408533 SeHCys and Ser are dehydrated into SeCysta by Cbs TAS Rattus norvegicus 15377 R-RNO-2408538 https://reactome.org/PathwayBrowser/#/R-RNO-2408538 MeSec is hydrolysed to MeSeH by PXLP-K211-Cth TAS Rattus norvegicus 15377 R-RNO-2408551 https://reactome.org/PathwayBrowser/#/R-RNO-2408551 SeMet is converted to AdoSeMet by MAT IEA Rattus norvegicus 15377 R-RNO-2408553 https://reactome.org/PathwayBrowser/#/R-RNO-2408553 SeO3(2-) combines with GSH to form GSSeSG and GSSG TAS Rattus norvegicus 15377 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 15377 R-RNO-2454118 https://reactome.org/PathwayBrowser/#/R-RNO-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Rattus norvegicus 15377 R-RNO-2465924 https://reactome.org/PathwayBrowser/#/R-RNO-2465924 OPN1LW binds 11cRAL IEA Rattus norvegicus 15377 R-RNO-2466085 https://reactome.org/PathwayBrowser/#/R-RNO-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Rattus norvegicus 15377 R-RNO-2509793 https://reactome.org/PathwayBrowser/#/R-RNO-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Rattus norvegicus 15377 R-RNO-2509816 https://reactome.org/PathwayBrowser/#/R-RNO-2509816 NUDT16 hydrolyses IDP to IMP IEA Rattus norvegicus 15377 R-RNO-2509827 https://reactome.org/PathwayBrowser/#/R-RNO-2509827 ITPA hydrolyses ITP to IMP IEA Rattus norvegicus 15377 R-RNO-2509831 https://reactome.org/PathwayBrowser/#/R-RNO-2509831 ITPA hydrolyses XTP to XMP IEA Rattus norvegicus 15377 R-RNO-2509838 https://reactome.org/PathwayBrowser/#/R-RNO-2509838 ITPA hydrolyses dITP to dIMP IEA Rattus norvegicus 15377 R-RNO-2529015 https://reactome.org/PathwayBrowser/#/R-RNO-2529015 Dephosphorylation of CK2-modified condensin I IEA Rattus norvegicus 15377 R-RNO-2584246 https://reactome.org/PathwayBrowser/#/R-RNO-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Rattus norvegicus 15377 R-RNO-2632521 https://reactome.org/PathwayBrowser/#/R-RNO-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Rattus norvegicus 15377 R-RNO-265783 https://reactome.org/PathwayBrowser/#/R-RNO-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Rattus norvegicus 15377 R-RNO-266012 https://reactome.org/PathwayBrowser/#/R-RNO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Rattus norvegicus 15377 R-RNO-266046 https://reactome.org/PathwayBrowser/#/R-RNO-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Rattus norvegicus 15377 R-RNO-266051 https://reactome.org/PathwayBrowser/#/R-RNO-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Rattus norvegicus 15377 R-RNO-266072 https://reactome.org/PathwayBrowser/#/R-RNO-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Rattus norvegicus 15377 R-RNO-266082 https://reactome.org/PathwayBrowser/#/R-RNO-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Rattus norvegicus 15377 R-RNO-2730847 https://reactome.org/PathwayBrowser/#/R-RNO-2730847 Hydrolysis of PIP2 by PLCG IEA Rattus norvegicus 15377 R-RNO-2730849 https://reactome.org/PathwayBrowser/#/R-RNO-2730849 Calcineurin binds and dephosphorylates NFAT IEA Rattus norvegicus 15377 R-RNO-2855047 https://reactome.org/PathwayBrowser/#/R-RNO-2855047 Hydrolysis of internal thioester in C4b IEA Rattus norvegicus 15377 R-RNO-2995330 https://reactome.org/PathwayBrowser/#/R-RNO-2995330 COX10 transforms heme to heme O IEA Rattus norvegicus 15377 R-RNO-2995334 https://reactome.org/PathwayBrowser/#/R-RNO-2995334 COX15 transforms heme O to heme A IEA Rattus norvegicus 15377 R-RNO-2995388 https://reactome.org/PathwayBrowser/#/R-RNO-2995388 PP2A dephosphorylates BANF1 IEA Rattus norvegicus 15377 R-RNO-3002811 https://reactome.org/PathwayBrowser/#/R-RNO-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Rattus norvegicus 15377 R-RNO-3095901 https://reactome.org/PathwayBrowser/#/R-RNO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Rattus norvegicus 15377 R-RNO-3204311 https://reactome.org/PathwayBrowser/#/R-RNO-3204311 AOX1 oxidises PXL to PDXate IEA Rattus norvegicus 15377 R-RNO-3215295 https://reactome.org/PathwayBrowser/#/R-RNO-3215295 USP7 deubiquitinates MDM2 IEA Rattus norvegicus 15377 R-RNO-3215310 https://reactome.org/PathwayBrowser/#/R-RNO-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Rattus norvegicus 15377 R-RNO-3247569 https://reactome.org/PathwayBrowser/#/R-RNO-3247569 PADI4 deiminates Histones IEA Rattus norvegicus 15377 R-RNO-3262512 https://reactome.org/PathwayBrowser/#/R-RNO-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Rattus norvegicus 15377 R-RNO-3322995 https://reactome.org/PathwayBrowser/#/R-RNO-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Rattus norvegicus 15377 R-RNO-3323013 https://reactome.org/PathwayBrowser/#/R-RNO-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 15377 R-RNO-3341277 https://reactome.org/PathwayBrowser/#/R-RNO-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 15377 R-RNO-3341296 https://reactome.org/PathwayBrowser/#/R-RNO-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Rattus norvegicus 15377 R-RNO-3341343 https://reactome.org/PathwayBrowser/#/R-RNO-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Rattus norvegicus 15377 R-RNO-3341397 https://reactome.org/PathwayBrowser/#/R-RNO-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 15377 R-RNO-3343700 https://reactome.org/PathwayBrowser/#/R-RNO-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 15377 R-RNO-3371467 https://reactome.org/PathwayBrowser/#/R-RNO-3371467 SIRT1 deacetylates HSF1 IEA Rattus norvegicus 15377 R-RNO-350604 https://reactome.org/PathwayBrowser/#/R-RNO-350604 Agmatine + H2O <=> putrescine + urea IEA Rattus norvegicus 15377 R-RNO-350901 https://reactome.org/PathwayBrowser/#/R-RNO-350901 Iodide is organified IEA Rattus norvegicus 15377 R-RNO-3640872 https://reactome.org/PathwayBrowser/#/R-RNO-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Rattus norvegicus 15377 R-RNO-3697882 https://reactome.org/PathwayBrowser/#/R-RNO-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Rattus norvegicus 15377 R-RNO-3697894 https://reactome.org/PathwayBrowser/#/R-RNO-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Rattus norvegicus 15377 R-RNO-374909 https://reactome.org/PathwayBrowser/#/R-RNO-374909 Catabolism of Noradrenaline IEA Rattus norvegicus 15377 R-RNO-377643 https://reactome.org/PathwayBrowser/#/R-RNO-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Rattus norvegicus 15377 R-RNO-3781018 https://reactome.org/PathwayBrowser/#/R-RNO-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Rattus norvegicus 15377 R-RNO-379382 https://reactome.org/PathwayBrowser/#/R-RNO-379382 MAOA:FAD deaminates DA to DOPAC IEA Rattus norvegicus 15377 R-RNO-379395 https://reactome.org/PathwayBrowser/#/R-RNO-379395 MAOA:FAD deaminates 3MT to HVA IEA Rattus norvegicus 15377 R-RNO-380949 https://reactome.org/PathwayBrowser/#/R-RNO-380949 AMPK is dephosphorylated IEA Rattus norvegicus 15377 R-RNO-382553 https://reactome.org/PathwayBrowser/#/R-RNO-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Rattus norvegicus 15377 R-RNO-382560 https://reactome.org/PathwayBrowser/#/R-RNO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Rattus norvegicus 15377 R-RNO-382575 https://reactome.org/PathwayBrowser/#/R-RNO-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Rattus norvegicus 15377 R-RNO-383190 https://reactome.org/PathwayBrowser/#/R-RNO-383190 HCO3- transport through ion channel IEA Rattus norvegicus 15377 R-RNO-389821 https://reactome.org/PathwayBrowser/#/R-RNO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Rattus norvegicus 15377 R-RNO-389862 https://reactome.org/PathwayBrowser/#/R-RNO-389862 Conversion of glyoxylate to oxalate IEA Rattus norvegicus 15377 R-RNO-389986 https://reactome.org/PathwayBrowser/#/R-RNO-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-390252 https://reactome.org/PathwayBrowser/#/R-RNO-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-390304 https://reactome.org/PathwayBrowser/#/R-RNO-390304 acetyl-CoA + H2O => acetate + CoASH IEA Rattus norvegicus 15377 R-RNO-390329 https://reactome.org/PathwayBrowser/#/R-RNO-390329 Dephosphorylation of AKT by PP2A IEA Rattus norvegicus 15377 R-RNO-399998 https://reactome.org/PathwayBrowser/#/R-RNO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Rattus norvegicus 15377 R-RNO-4084976 https://reactome.org/PathwayBrowser/#/R-RNO-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Rattus norvegicus 15377 R-RNO-4084989 https://reactome.org/PathwayBrowser/#/R-RNO-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Rattus norvegicus 15377 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 15377 R-RNO-4084999 https://reactome.org/PathwayBrowser/#/R-RNO-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 15377 R-RNO-4085021 https://reactome.org/PathwayBrowser/#/R-RNO-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Rattus norvegicus 15377 R-RNO-4085029 https://reactome.org/PathwayBrowser/#/R-RNO-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 15377 R-RNO-4086392 https://reactome.org/PathwayBrowser/#/R-RNO-4086392 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 15377 R-RNO-4088141 https://reactome.org/PathwayBrowser/#/R-RNO-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Rattus norvegicus 15377 R-RNO-4093339 https://reactome.org/PathwayBrowser/#/R-RNO-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Rattus norvegicus 15377 R-RNO-416559 https://reactome.org/PathwayBrowser/#/R-RNO-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Rattus norvegicus 15377 R-RNO-418553 https://reactome.org/PathwayBrowser/#/R-RNO-418553 cAMP degradation by Phosphodiesterases IEA Rattus norvegicus 15377 R-RNO-426043 https://reactome.org/PathwayBrowser/#/R-RNO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Rattus norvegicus 15377 R-RNO-428205 https://reactome.org/PathwayBrowser/#/R-RNO-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Rattus norvegicus 15377 R-RNO-428231 https://reactome.org/PathwayBrowser/#/R-RNO-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Rattus norvegicus 15377 R-RNO-428259 https://reactome.org/PathwayBrowser/#/R-RNO-428259 DEGS1 dehydrogenates dihydroceramide IEA Rattus norvegicus 15377 R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 15377 R-RNO-428262 https://reactome.org/PathwayBrowser/#/R-RNO-428262 ACER3 hydrolyzes phytoceramide IEA Rattus norvegicus 15377 R-RNO-428664 https://reactome.org/PathwayBrowser/#/R-RNO-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Rattus norvegicus 15377 R-RNO-428690 https://reactome.org/PathwayBrowser/#/R-RNO-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Rattus norvegicus 15377 R-RNO-428696 https://reactome.org/PathwayBrowser/#/R-RNO-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Rattus norvegicus 15377 R-RNO-429157 https://reactome.org/PathwayBrowser/#/R-RNO-429157 ABCC4 accumulation of dense granule contents IEA Rattus norvegicus 15377 R-RNO-429860 https://reactome.org/PathwayBrowser/#/R-RNO-429860 DCP1-DCP2 complex decaps mRNA IEA Rattus norvegicus 15377 R-RNO-429961 https://reactome.org/PathwayBrowser/#/R-RNO-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Rattus norvegicus 15377 R-RNO-430021 https://reactome.org/PathwayBrowser/#/R-RNO-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Rattus norvegicus 15377 R-RNO-430028 https://reactome.org/PathwayBrowser/#/R-RNO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Rattus norvegicus 15377 R-RNO-432010 https://reactome.org/PathwayBrowser/#/R-RNO-432010 Aquaporin-1 passively transports water into cell IEA Rattus norvegicus 15377 R-RNO-432054 https://reactome.org/PathwayBrowser/#/R-RNO-432054 Aquaporin-1 passively transports water out of cell IEA Rattus norvegicus 15377 R-RNO-432065 https://reactome.org/PathwayBrowser/#/R-RNO-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Rattus norvegicus 15377 R-RNO-432067 https://reactome.org/PathwayBrowser/#/R-RNO-432067 Aquaporin-4 passively transports water out of cell IEA Rattus norvegicus 15377 R-RNO-4419948 https://reactome.org/PathwayBrowser/#/R-RNO-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Rattus norvegicus 15377 R-RNO-445714 https://reactome.org/PathwayBrowser/#/R-RNO-445714 Aquaporin-3 passively transports water out of cell IEA Rattus norvegicus 15377 R-RNO-446200 https://reactome.org/PathwayBrowser/#/R-RNO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Rattus norvegicus 15377 R-RNO-449937 https://reactome.org/PathwayBrowser/#/R-RNO-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Rattus norvegicus 15377 R-RNO-452036 https://reactome.org/PathwayBrowser/#/R-RNO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Rattus norvegicus 15377 R-RNO-4551451 https://reactome.org/PathwayBrowser/#/R-RNO-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Rattus norvegicus 15377 R-RNO-4641236 https://reactome.org/PathwayBrowser/#/R-RNO-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Rattus norvegicus 15377 R-RNO-504054 https://reactome.org/PathwayBrowser/#/R-RNO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Rattus norvegicus 15377 R-RNO-507868 https://reactome.org/PathwayBrowser/#/R-RNO-507868 Aquaporins passively transport water into cells IEA Rattus norvegicus 15377 R-RNO-507870 https://reactome.org/PathwayBrowser/#/R-RNO-507870 Aquaporins passively transport water out of cells IEA Rattus norvegicus 15377 R-RNO-508308 https://reactome.org/PathwayBrowser/#/R-RNO-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Rattus norvegicus 15377 R-RNO-5221130 https://reactome.org/PathwayBrowser/#/R-RNO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Rattus norvegicus 15377 R-RNO-5223317 https://reactome.org/PathwayBrowser/#/R-RNO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Rattus norvegicus 15377 R-RNO-5251955 https://reactome.org/PathwayBrowser/#/R-RNO-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Rattus norvegicus 15377 R-RNO-5251959 https://reactome.org/PathwayBrowser/#/R-RNO-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Rattus norvegicus 15377 R-RNO-5251989 https://reactome.org/PathwayBrowser/#/R-RNO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Rattus norvegicus 15377 R-RNO-5263614 https://reactome.org/PathwayBrowser/#/R-RNO-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Rattus norvegicus 15377 R-RNO-5263616 https://reactome.org/PathwayBrowser/#/R-RNO-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Rattus norvegicus 15377 R-RNO-5333610 https://reactome.org/PathwayBrowser/#/R-RNO-5333610 Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec-tRNA(Sec):Eefsec:GTP is hydrolysed to Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec and Eefsec:GDP by Eefsec TAS Rattus norvegicus 15377 R-RNO-5333611 https://reactome.org/PathwayBrowser/#/R-RNO-5333611 MeSebGalNac is hydrolysed to MeSeH and bGalNac TAS Rattus norvegicus 15377 R-RNO-5362459 https://reactome.org/PathwayBrowser/#/R-RNO-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Rattus norvegicus 15377 R-RNO-5362522 https://reactome.org/PathwayBrowser/#/R-RNO-5362522 ALDHs oxidise atRAL to atRA IEA Rattus norvegicus 15377 R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 15377 R-RNO-5423647 https://reactome.org/PathwayBrowser/#/R-RNO-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Rattus norvegicus 15377 R-RNO-5423664 https://reactome.org/PathwayBrowser/#/R-RNO-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Rattus norvegicus 15377 R-RNO-5423672 https://reactome.org/PathwayBrowser/#/R-RNO-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Rattus norvegicus 15377 R-RNO-5423678 https://reactome.org/PathwayBrowser/#/R-RNO-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Rattus norvegicus 15377 R-RNO-5433072 https://reactome.org/PathwayBrowser/#/R-RNO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Rattus norvegicus 15377 R-RNO-5433074 https://reactome.org/PathwayBrowser/#/R-RNO-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 15377 R-RNO-548843 https://reactome.org/PathwayBrowser/#/R-RNO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Rattus norvegicus 15377 R-RNO-5603114 https://reactome.org/PathwayBrowser/#/R-RNO-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Rattus norvegicus 15377 R-RNO-5607735 https://reactome.org/PathwayBrowser/#/R-RNO-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Rattus norvegicus 15377 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 15377 R-RNO-5623513 https://reactome.org/PathwayBrowser/#/R-RNO-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Rattus norvegicus 15377 R-RNO-5628905 https://reactome.org/PathwayBrowser/#/R-RNO-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Rattus norvegicus 15377 R-RNO-5631885 https://reactome.org/PathwayBrowser/#/R-RNO-5631885 PRDX1 overoxidizes IEA Rattus norvegicus 15377 R-RNO-5649705 https://reactome.org/PathwayBrowser/#/R-RNO-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Rattus norvegicus 15377 R-RNO-5651828 https://reactome.org/PathwayBrowser/#/R-RNO-5651828 PARG dePARylates PARP1,PARP2 IEA Rattus norvegicus 15377 R-RNO-5653770 https://reactome.org/PathwayBrowser/#/R-RNO-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Rattus norvegicus 15377 R-RNO-5653786 https://reactome.org/PathwayBrowser/#/R-RNO-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Rattus norvegicus 15377 R-RNO-5655945 https://reactome.org/PathwayBrowser/#/R-RNO-5655945 Olah hydrolyzes decanoyl-Fasn dimer to decanoate and Fasn dimer TAS Rattus norvegicus 15377 R-RNO-5659861 https://reactome.org/PathwayBrowser/#/R-RNO-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 15377 R-RNO-5662692 https://reactome.org/PathwayBrowser/#/R-RNO-5662692 Dopa is oxidized to dopaquinone by TYR IEA Rattus norvegicus 15377 R-RNO-5665809 https://reactome.org/PathwayBrowser/#/R-RNO-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Rattus norvegicus 15377 R-RNO-5672957 https://reactome.org/PathwayBrowser/#/R-RNO-5672957 PP2A dephosphorylates KSR1 IEA Rattus norvegicus 15377 R-RNO-5672961 https://reactome.org/PathwayBrowser/#/R-RNO-5672961 PP2A dephosphorylates inactive RAFs IEA Rattus norvegicus 15377 R-RNO-5675373 https://reactome.org/PathwayBrowser/#/R-RNO-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Rattus norvegicus 15377 R-RNO-5675376 https://reactome.org/PathwayBrowser/#/R-RNO-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Rattus norvegicus 15377 R-RNO-5675431 https://reactome.org/PathwayBrowser/#/R-RNO-5675431 PP2A dephosphorylates RAF1 IEA Rattus norvegicus 15377 R-RNO-5675433 https://reactome.org/PathwayBrowser/#/R-RNO-5675433 PP5 dephosphorylates RAF1 S338 IEA Rattus norvegicus 15377 R-RNO-5676637 https://reactome.org/PathwayBrowser/#/R-RNO-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Rattus norvegicus 15377 R-RNO-5678327 https://reactome.org/PathwayBrowser/#/R-RNO-5678327 MIOX oxidises Ins to GlcA IEA Rattus norvegicus 15377 R-RNO-5678706 https://reactome.org/PathwayBrowser/#/R-RNO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Rattus norvegicus 15377 R-RNO-5678863 https://reactome.org/PathwayBrowser/#/R-RNO-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Rattus norvegicus 15377 R-RNO-5679041 https://reactome.org/PathwayBrowser/#/R-RNO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 15377 R-RNO-5682285 https://reactome.org/PathwayBrowser/#/R-RNO-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Rattus norvegicus 15377 R-RNO-5683405 https://reactome.org/PathwayBrowser/#/R-RNO-5683405 PPP5C dephosphorylates TP53BP1 IEA Rattus norvegicus 15377 R-RNO-5683714 https://reactome.org/PathwayBrowser/#/R-RNO-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Rattus norvegicus 15377 R-RNO-5683967 https://reactome.org/PathwayBrowser/#/R-RNO-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Rattus norvegicus 15377 R-RNO-5684864 https://reactome.org/PathwayBrowser/#/R-RNO-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Rattus norvegicus 15377 R-RNO-5685902 https://reactome.org/PathwayBrowser/#/R-RNO-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Rattus norvegicus 15377 R-RNO-5685994 https://reactome.org/PathwayBrowser/#/R-RNO-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Rattus norvegicus 15377 R-RNO-5687464 https://reactome.org/PathwayBrowser/#/R-RNO-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Rattus norvegicus 15377 R-RNO-5687664 https://reactome.org/PathwayBrowser/#/R-RNO-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Rattus norvegicus 15377 R-RNO-5687758 https://reactome.org/PathwayBrowser/#/R-RNO-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Rattus norvegicus 15377 R-RNO-5688797 https://reactome.org/PathwayBrowser/#/R-RNO-5688797 ATXN3 family cleave Ub chains IEA Rattus norvegicus 15377 R-RNO-5688837 https://reactome.org/PathwayBrowser/#/R-RNO-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Rattus norvegicus 15377 R-RNO-5689000 https://reactome.org/PathwayBrowser/#/R-RNO-5689000 AADAC deacetylates PHEN IEA Rattus norvegicus 15377 R-RNO-5689950 https://reactome.org/PathwayBrowser/#/R-RNO-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Rattus norvegicus 15377 R-RNO-5689972 https://reactome.org/PathwayBrowser/#/R-RNO-5689972 USP2 deubiquitinates MDM2,MDM4 IEA Rattus norvegicus 15377 R-RNO-5689973 https://reactome.org/PathwayBrowser/#/R-RNO-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Rattus norvegicus 15377 R-RNO-5690042 https://reactome.org/PathwayBrowser/#/R-RNO-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 15377 R-RNO-5690043 https://reactome.org/PathwayBrowser/#/R-RNO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 15377 R-RNO-5690046 https://reactome.org/PathwayBrowser/#/R-RNO-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Rattus norvegicus 15377 R-RNO-5690066 https://reactome.org/PathwayBrowser/#/R-RNO-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 15377 R-RNO-5690080 https://reactome.org/PathwayBrowser/#/R-RNO-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Rattus norvegicus 15377 R-RNO-5690152 https://reactome.org/PathwayBrowser/#/R-RNO-5690152 USP5 cleaves polyubiquitin IEA Rattus norvegicus 15377 R-RNO-5690157 https://reactome.org/PathwayBrowser/#/R-RNO-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Rattus norvegicus 15377 R-RNO-5690159 https://reactome.org/PathwayBrowser/#/R-RNO-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Rattus norvegicus 15377 R-RNO-5690196 https://reactome.org/PathwayBrowser/#/R-RNO-5690196 USP8 deubiquitinates RNF128 IEA Rattus norvegicus 15377 R-RNO-5690319 https://reactome.org/PathwayBrowser/#/R-RNO-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Rattus norvegicus 15377 R-RNO-5690517 https://reactome.org/PathwayBrowser/#/R-RNO-5690517 PPT1 hydrolyses palmitoylated proteins IEA Rattus norvegicus 15377 R-RNO-5690565 https://reactome.org/PathwayBrowser/#/R-RNO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Rattus norvegicus 15377 R-RNO-5690759 https://reactome.org/PathwayBrowser/#/R-RNO-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Rattus norvegicus 15377 R-RNO-5690790 https://reactome.org/PathwayBrowser/#/R-RNO-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Rattus norvegicus 15377 R-RNO-5690808 https://reactome.org/PathwayBrowser/#/R-RNO-5690808 UCHL3, SENP8 cleave NEDD8 IEA Rattus norvegicus 15377 R-RNO-5690856 https://reactome.org/PathwayBrowser/#/R-RNO-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Rattus norvegicus 15377 R-RNO-5690870 https://reactome.org/PathwayBrowser/#/R-RNO-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Rattus norvegicus 15377 R-RNO-5691381 https://reactome.org/PathwayBrowser/#/R-RNO-5691381 MYSM1 deubiquitinates Histone H2A IEA Rattus norvegicus 15377 R-RNO-5691411 https://reactome.org/PathwayBrowser/#/R-RNO-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Rattus norvegicus 15377 R-RNO-5691439 https://reactome.org/PathwayBrowser/#/R-RNO-5691439 BRISC complex deubiquitinates NLRP3 IEA Rattus norvegicus 15377 R-RNO-5691507 https://reactome.org/PathwayBrowser/#/R-RNO-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Rattus norvegicus 15377 R-RNO-5691512 https://reactome.org/PathwayBrowser/#/R-RNO-5691512 APEH hydrolyses NAc-Ser-protein IEA Rattus norvegicus 15377 R-RNO-5692261 https://reactome.org/PathwayBrowser/#/R-RNO-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Rattus norvegicus 15377 R-RNO-5692283 https://reactome.org/PathwayBrowser/#/R-RNO-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Rattus norvegicus 15377 R-RNO-5692462 https://reactome.org/PathwayBrowser/#/R-RNO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Rattus norvegicus 15377 R-RNO-5692480 https://reactome.org/PathwayBrowser/#/R-RNO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Rattus norvegicus 15377 R-RNO-5692754 https://reactome.org/PathwayBrowser/#/R-RNO-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Rattus norvegicus 15377 R-RNO-5693153 https://reactome.org/PathwayBrowser/#/R-RNO-5693153 PPM1K dephosphorylates p-BCKDH IEA Rattus norvegicus 15377 R-RNO-5693373 https://reactome.org/PathwayBrowser/#/R-RNO-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Rattus norvegicus 15377 R-RNO-5693608 https://reactome.org/PathwayBrowser/#/R-RNO-5693608 Initial resection of double-strand break ends IEA Rattus norvegicus 15377 R-RNO-5693691 https://reactome.org/PathwayBrowser/#/R-RNO-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Rattus norvegicus 15377 R-RNO-5693724 https://reactome.org/PathwayBrowser/#/R-RNO-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Rattus norvegicus 15377 R-RNO-5693742 https://reactome.org/PathwayBrowser/#/R-RNO-5693742 FAAH hydrolyses AEA to AA and ETA IEA Rattus norvegicus 15377 R-RNO-5693761 https://reactome.org/PathwayBrowser/#/R-RNO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Rattus norvegicus 15377 R-RNO-5693807 https://reactome.org/PathwayBrowser/#/R-RNO-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Rattus norvegicus 15377 R-RNO-5694077 https://reactome.org/PathwayBrowser/#/R-RNO-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Rattus norvegicus 15377 R-RNO-5694109 https://reactome.org/PathwayBrowser/#/R-RNO-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Rattus norvegicus 15377 R-RNO-5694126 https://reactome.org/PathwayBrowser/#/R-RNO-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Rattus norvegicus 15377 R-RNO-5694137 https://reactome.org/PathwayBrowser/#/R-RNO-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Rattus norvegicus 15377 R-RNO-5694421 https://reactome.org/PathwayBrowser/#/R-RNO-5694421 PP6 dephosphorylates SEC24 IEA Rattus norvegicus 15377 R-RNO-5694462 https://reactome.org/PathwayBrowser/#/R-RNO-5694462 ABHD6,12 hydrolyse 3AG IEA Rattus norvegicus 15377 R-RNO-5694485 https://reactome.org/PathwayBrowser/#/R-RNO-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Rattus norvegicus 15377 R-RNO-5694563 https://reactome.org/PathwayBrowser/#/R-RNO-5694563 ABHD10 hydrolyses MPAG IEA Rattus norvegicus 15377 R-RNO-5694583 https://reactome.org/PathwayBrowser/#/R-RNO-5694583 ABHD4 hydrolyses NAPE IEA Rattus norvegicus 15377 R-RNO-5695964 https://reactome.org/PathwayBrowser/#/R-RNO-5695964 ABHD14B hydrolyses PNPB IEA Rattus norvegicus 15377 R-RNO-5696049 https://reactome.org/PathwayBrowser/#/R-RNO-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 15377 R-RNO-5696080 https://reactome.org/PathwayBrowser/#/R-RNO-5696080 ALDH3B1 oxidises HXAL to PALM IEA Rattus norvegicus 15377 R-RNO-5696091 https://reactome.org/PathwayBrowser/#/R-RNO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Rattus norvegicus 15377 R-RNO-5696101 https://reactome.org/PathwayBrowser/#/R-RNO-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Rattus norvegicus 15377 R-RNO-5696119 https://reactome.org/PathwayBrowser/#/R-RNO-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Rattus norvegicus 15377 R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 15377 R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 15377 R-RNO-5696197 https://reactome.org/PathwayBrowser/#/R-RNO-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Rattus norvegicus 15377 R-RNO-5696230 https://reactome.org/PathwayBrowser/#/R-RNO-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Rattus norvegicus 15377 R-RNO-5696365 https://reactome.org/PathwayBrowser/#/R-RNO-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Rattus norvegicus 15377 R-RNO-5696408 https://reactome.org/PathwayBrowser/#/R-RNO-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Rattus norvegicus 15377 R-RNO-5696415 https://reactome.org/PathwayBrowser/#/R-RNO-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Rattus norvegicus 15377 R-RNO-5696465 https://reactome.org/PathwayBrowser/#/R-RNO-5696465 USP45 deubiquitinates ERCC1 IEA Rattus norvegicus 15377 R-RNO-5696534 https://reactome.org/PathwayBrowser/#/R-RNO-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Rattus norvegicus 15377 R-RNO-5696564 https://reactome.org/PathwayBrowser/#/R-RNO-5696564 USP25 deubiquitinates DDX58 IEA Rattus norvegicus 15377 R-RNO-5696600 https://reactome.org/PathwayBrowser/#/R-RNO-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Rattus norvegicus 15377 R-RNO-5696605 https://reactome.org/PathwayBrowser/#/R-RNO-5696605 USP12, USP26 deubiquitinate AR IEA Rattus norvegicus 15377 R-RNO-5696627 https://reactome.org/PathwayBrowser/#/R-RNO-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Rattus norvegicus 15377 R-RNO-5696872 https://reactome.org/PathwayBrowser/#/R-RNO-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Rattus norvegicus 15377 R-RNO-5696914 https://reactome.org/PathwayBrowser/#/R-RNO-5696914 USP28 deubiquitinates CLSPN and MYC IEA Rattus norvegicus 15377 R-RNO-5696945 https://reactome.org/PathwayBrowser/#/R-RNO-5696945 USP33 deubiquitinates CCP110,ARRB IEA Rattus norvegicus 15377 R-RNO-5696947 https://reactome.org/PathwayBrowser/#/R-RNO-5696947 USP47 deubiquitinates POLB IEA Rattus norvegicus 15377 R-RNO-5696958 https://reactome.org/PathwayBrowser/#/R-RNO-5696958 USP44 deubiquitinates CDC20 IEA Rattus norvegicus 15377 R-RNO-5696968 https://reactome.org/PathwayBrowser/#/R-RNO-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Rattus norvegicus 15377 R-RNO-5696997 https://reactome.org/PathwayBrowser/#/R-RNO-5696997 USP24 deubiquitinates DDB2 IEA Rattus norvegicus 15377 R-RNO-5697009 https://reactome.org/PathwayBrowser/#/R-RNO-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Rattus norvegicus 15377 R-RNO-622387 https://reactome.org/PathwayBrowser/#/R-RNO-622387 PIP2 hydrolysis TAS Rattus norvegicus 15377 R-RNO-6781764 https://reactome.org/PathwayBrowser/#/R-RNO-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Rattus norvegicus 15377 R-RNO-6781779 https://reactome.org/PathwayBrowser/#/R-RNO-6781779 USP13 deubiquitinates BECN1,USP10 IEA Rattus norvegicus 15377 R-RNO-6781814 https://reactome.org/PathwayBrowser/#/R-RNO-6781814 USP19 deubiquitinates RNF123 IEA Rattus norvegicus 15377 R-RNO-6781897 https://reactome.org/PathwayBrowser/#/R-RNO-6781897 USP11 deubiquitinates NFKBIA IEA Rattus norvegicus 15377 R-RNO-6782069 https://reactome.org/PathwayBrowser/#/R-RNO-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Rattus norvegicus 15377 R-RNO-6782106 https://reactome.org/PathwayBrowser/#/R-RNO-6782106 USP10 deubiquitinates SNX3, CFTR IEA Rattus norvegicus 15377 R-RNO-6782628 https://reactome.org/PathwayBrowser/#/R-RNO-6782628 USP8 deubiquitinates STAM2:HGS IEA Rattus norvegicus 15377 R-RNO-6782820 https://reactome.org/PathwayBrowser/#/R-RNO-6782820 USP17 deubiquitinates SUDS3 IEA Rattus norvegicus 15377 R-RNO-6783177 https://reactome.org/PathwayBrowser/#/R-RNO-6783177 USP21 deubiquitinates GATA3,IL33 IEA Rattus norvegicus 15377 R-RNO-6783221 https://reactome.org/PathwayBrowser/#/R-RNO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Rattus norvegicus 15377 R-RNO-6784959 https://reactome.org/PathwayBrowser/#/R-RNO-6784959 BPHL hydrolyses VACV to ACV IEA Rattus norvegicus 15377 R-RNO-6786190 https://reactome.org/PathwayBrowser/#/R-RNO-6786190 CMBL hydrolyses OM to OLMS IEA Rattus norvegicus 15377 R-RNO-6786239 https://reactome.org/PathwayBrowser/#/R-RNO-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Rattus norvegicus 15377 R-RNO-6786421 https://reactome.org/PathwayBrowser/#/R-RNO-6786421 CHIA hydrolyses chitin IEA Rattus norvegicus 15377 R-RNO-6786650 https://reactome.org/PathwayBrowser/#/R-RNO-6786650 DDHD1,2 hydrolyse PA IEA Rattus norvegicus 15377 R-RNO-6786652 https://reactome.org/PathwayBrowser/#/R-RNO-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Rattus norvegicus 15377 R-RNO-6787632 https://reactome.org/PathwayBrowser/#/R-RNO-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Rattus norvegicus 15377 R-RNO-6788295 https://reactome.org/PathwayBrowser/#/R-RNO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Rattus norvegicus 15377 R-RNO-6788912 https://reactome.org/PathwayBrowser/#/R-RNO-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Rattus norvegicus 15377 R-RNO-6789031 https://reactome.org/PathwayBrowser/#/R-RNO-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 15377 R-RNO-6789126 https://reactome.org/PathwayBrowser/#/R-RNO-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 15377 R-RNO-6789310 https://reactome.org/PathwayBrowser/#/R-RNO-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Rattus norvegicus 15377 R-RNO-6792445 https://reactome.org/PathwayBrowser/#/R-RNO-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Rattus norvegicus 15377 R-RNO-6792863 https://reactome.org/PathwayBrowser/#/R-RNO-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Rattus norvegicus 15377 R-RNO-6797627 https://reactome.org/PathwayBrowser/#/R-RNO-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Rattus norvegicus 15377 R-RNO-6797630 https://reactome.org/PathwayBrowser/#/R-RNO-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Rattus norvegicus 15377 R-RNO-6797653 https://reactome.org/PathwayBrowser/#/R-RNO-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Rattus norvegicus 15377 R-RNO-6797913 https://reactome.org/PathwayBrowser/#/R-RNO-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Rattus norvegicus 15377 R-RNO-6797955 https://reactome.org/PathwayBrowser/#/R-RNO-6797955 ALDH7A1 oxidises BETALD to BET IEA Rattus norvegicus 15377 R-RNO-6799545 https://reactome.org/PathwayBrowser/#/R-RNO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Rattus norvegicus 15377 R-RNO-6799581 https://reactome.org/PathwayBrowser/#/R-RNO-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Rattus norvegicus 15377 R-RNO-6799604 https://reactome.org/PathwayBrowser/#/R-RNO-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Rattus norvegicus 15377 R-RNO-6799695 https://reactome.org/PathwayBrowser/#/R-RNO-6799695 GPX5,6 reduce H2O2 to H2O IEA Rattus norvegicus 15377 R-RNO-6799977 https://reactome.org/PathwayBrowser/#/R-RNO-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Rattus norvegicus 15377 R-RNO-6800198 https://reactome.org/PathwayBrowser/#/R-RNO-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Rattus norvegicus 15377 R-RNO-6800200 https://reactome.org/PathwayBrowser/#/R-RNO-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Rattus norvegicus 15377 R-RNO-6800299 https://reactome.org/PathwayBrowser/#/R-RNO-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Rattus norvegicus 15377 R-RNO-6801462 https://reactome.org/PathwayBrowser/#/R-RNO-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Rattus norvegicus 15377 R-RNO-6803545 https://reactome.org/PathwayBrowser/#/R-RNO-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Rattus norvegicus 15377 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 15377 R-RNO-6803789 https://reactome.org/PathwayBrowser/#/R-RNO-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Rattus norvegicus 15377 R-RNO-6805650 https://reactome.org/PathwayBrowser/#/R-RNO-6805650 MTA2-NuRD complex deacetylates TP53 IEA Rattus norvegicus 15377 R-RNO-6807008 https://reactome.org/PathwayBrowser/#/R-RNO-6807008 PTPRJ dephosphorylates MET IEA Rattus norvegicus 15377 R-RNO-6807027 https://reactome.org/PathwayBrowser/#/R-RNO-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Rattus norvegicus 15377 R-RNO-6807053 https://reactome.org/PathwayBrowser/#/R-RNO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Rattus norvegicus 15377 R-RNO-6807118 https://reactome.org/PathwayBrowser/#/R-RNO-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Rattus norvegicus 15377 R-RNO-6807206 https://reactome.org/PathwayBrowser/#/R-RNO-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Rattus norvegicus 15377 R-RNO-6807214 https://reactome.org/PathwayBrowser/#/R-RNO-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Rattus norvegicus 15377 R-RNO-6808464 https://reactome.org/PathwayBrowser/#/R-RNO-6808464 ALDH3B2 oxidises HXAL to PALM IEA Rattus norvegicus 15377 R-RNO-6808487 https://reactome.org/PathwayBrowser/#/R-RNO-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 15377 R-RNO-6808496 https://reactome.org/PathwayBrowser/#/R-RNO-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 15377 R-RNO-6809263 https://reactome.org/PathwayBrowser/#/R-RNO-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-6809287 https://reactome.org/PathwayBrowser/#/R-RNO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Rattus norvegicus 15377 R-RNO-6809320 https://reactome.org/PathwayBrowser/#/R-RNO-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-6809325 https://reactome.org/PathwayBrowser/#/R-RNO-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Rattus norvegicus 15377 R-RNO-6809720 https://reactome.org/PathwayBrowser/#/R-RNO-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Rattus norvegicus 15377 R-RNO-6809777 https://reactome.org/PathwayBrowser/#/R-RNO-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Rattus norvegicus 15377 R-RNO-6809778 https://reactome.org/PathwayBrowser/#/R-RNO-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Rattus norvegicus 15377 R-RNO-6810076 https://reactome.org/PathwayBrowser/#/R-RNO-6810076 DDO oxidizes D-Asp to OA IEA Rattus norvegicus 15377 R-RNO-6810410 https://reactome.org/PathwayBrowser/#/R-RNO-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Rattus norvegicus 15377 R-RNO-6810464 https://reactome.org/PathwayBrowser/#/R-RNO-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Rattus norvegicus 15377 R-RNO-6810472 https://reactome.org/PathwayBrowser/#/R-RNO-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Rattus norvegicus 15377 R-RNO-6810474 https://reactome.org/PathwayBrowser/#/R-RNO-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Rattus norvegicus 15377 R-RNO-6811504 https://reactome.org/PathwayBrowser/#/R-RNO-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Rattus norvegicus 15377 R-RNO-6813720 https://reactome.org/PathwayBrowser/#/R-RNO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Rattus norvegicus 15377 R-RNO-6813740 https://reactome.org/PathwayBrowser/#/R-RNO-6813740 GDE1 hydrolyzes GroPIns IEA Rattus norvegicus 15377 R-RNO-6813749 https://reactome.org/PathwayBrowser/#/R-RNO-6813749 ALDH1A1 oxidises GA to DGA IEA Rattus norvegicus 15377 R-RNO-6814254 https://reactome.org/PathwayBrowser/#/R-RNO-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Rattus norvegicus 15377 R-RNO-6814797 https://reactome.org/PathwayBrowser/#/R-RNO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Rattus norvegicus 15377 R-RNO-69199 https://reactome.org/PathwayBrowser/#/R-RNO-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Rattus norvegicus 15377 R-RNO-70262 https://reactome.org/PathwayBrowser/#/R-RNO-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Rattus norvegicus 15377 R-RNO-70479 https://reactome.org/PathwayBrowser/#/R-RNO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Rattus norvegicus 15377 R-RNO-70494 https://reactome.org/PathwayBrowser/#/R-RNO-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Rattus norvegicus 15377 R-RNO-70569 https://reactome.org/PathwayBrowser/#/R-RNO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Rattus norvegicus 15377 R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Rattus norvegicus 15377 R-RNO-70599 https://reactome.org/PathwayBrowser/#/R-RNO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Rattus norvegicus 15377 R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Rattus norvegicus 15377 R-RNO-70609 https://reactome.org/PathwayBrowser/#/R-RNO-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Rattus norvegicus 15377 R-RNO-70679 https://reactome.org/PathwayBrowser/#/R-RNO-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Rattus norvegicus 15377 R-RNO-70785 https://reactome.org/PathwayBrowser/#/R-RNO-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Rattus norvegicus 15377 R-RNO-70870 https://reactome.org/PathwayBrowser/#/R-RNO-70870 ECHS1 hydrates methacrylyl-CoA IEA Rattus norvegicus 15377 R-RNO-70881 https://reactome.org/PathwayBrowser/#/R-RNO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Rattus norvegicus 15377 R-RNO-70903 https://reactome.org/PathwayBrowser/#/R-RNO-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Rattus norvegicus 15377 R-RNO-70906 https://reactome.org/PathwayBrowser/#/R-RNO-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Rattus norvegicus 15377 R-RNO-70938 https://reactome.org/PathwayBrowser/#/R-RNO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Rattus norvegicus 15377 R-RNO-70940 https://reactome.org/PathwayBrowser/#/R-RNO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Rattus norvegicus 15377 R-RNO-70941 https://reactome.org/PathwayBrowser/#/R-RNO-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Rattus norvegicus 15377 R-RNO-70975 https://reactome.org/PathwayBrowser/#/R-RNO-70975 CS acetylates OA to citrate IEA Rattus norvegicus 15377 R-RNO-70982 https://reactome.org/PathwayBrowser/#/R-RNO-70982 FH tetramer hydrates fumarate to L-malate IEA Rattus norvegicus 15377 R-RNO-71146 https://reactome.org/PathwayBrowser/#/R-RNO-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Rattus norvegicus 15377 R-RNO-71181 https://reactome.org/PathwayBrowser/#/R-RNO-71181 FAH cleaves 4FAA IEA Rattus norvegicus 15377 R-RNO-71200 https://reactome.org/PathwayBrowser/#/R-RNO-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Rattus norvegicus 15377 R-RNO-71217 https://reactome.org/PathwayBrowser/#/R-RNO-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Rattus norvegicus 15377 R-RNO-71260 https://reactome.org/PathwayBrowser/#/R-RNO-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Rattus norvegicus 15377 R-RNO-71296 https://reactome.org/PathwayBrowser/#/R-RNO-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Rattus norvegicus 15377 R-RNO-71660 https://reactome.org/PathwayBrowser/#/R-RNO-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Rattus norvegicus 15377 R-RNO-71676 https://reactome.org/PathwayBrowser/#/R-RNO-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Rattus norvegicus 15377 R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 15377 R-RNO-71723 https://reactome.org/PathwayBrowser/#/R-RNO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Rattus norvegicus 15377 R-RNO-71732 https://reactome.org/PathwayBrowser/#/R-RNO-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Rattus norvegicus 15377 R-RNO-71825 https://reactome.org/PathwayBrowser/#/R-RNO-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Rattus norvegicus 15377 R-RNO-73571 https://reactome.org/PathwayBrowser/#/R-RNO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Rattus norvegicus 15377 R-RNO-73577 https://reactome.org/PathwayBrowser/#/R-RNO-73577 CAD hexamer transforms L-Gln to CAP IEA Rattus norvegicus 15377 R-RNO-73589 https://reactome.org/PathwayBrowser/#/R-RNO-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Rattus norvegicus 15377 R-RNO-73591 https://reactome.org/PathwayBrowser/#/R-RNO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Rattus norvegicus 15377 R-RNO-73596 https://reactome.org/PathwayBrowser/#/R-RNO-73596 dCMP + H2O => dUMP + NH4+ IEA Rattus norvegicus 15377 R-RNO-73608 https://reactome.org/PathwayBrowser/#/R-RNO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Rattus norvegicus 15377 R-RNO-73618 https://reactome.org/PathwayBrowser/#/R-RNO-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Rattus norvegicus 15377 R-RNO-73620 https://reactome.org/PathwayBrowser/#/R-RNO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Rattus norvegicus 15377 R-RNO-73647 https://reactome.org/PathwayBrowser/#/R-RNO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Rattus norvegicus 15377 R-RNO-73666 https://reactome.org/PathwayBrowser/#/R-RNO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Rattus norvegicus 15377 R-RNO-73792 https://reactome.org/PathwayBrowser/#/R-RNO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Rattus norvegicus 15377 R-RNO-73794 https://reactome.org/PathwayBrowser/#/R-RNO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Rattus norvegicus 15377 R-RNO-73797 https://reactome.org/PathwayBrowser/#/R-RNO-73797 FAICAR => IMP + H2O IEA Rattus norvegicus 15377 R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 15377 R-RNO-73815 https://reactome.org/PathwayBrowser/#/R-RNO-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Rattus norvegicus 15377 R-RNO-74059 https://reactome.org/PathwayBrowser/#/R-RNO-74059 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 15377 R-RNO-74241 https://reactome.org/PathwayBrowser/#/R-RNO-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Rattus norvegicus 15377 R-RNO-74247 https://reactome.org/PathwayBrowser/#/R-RNO-74247 XDH oxidizes hypoxanthine to form xanthine IEA Rattus norvegicus 15377 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 15377 R-RNO-74255 https://reactome.org/PathwayBrowser/#/R-RNO-74255 Guanine + H2O => Xanthine + NH4+ IEA Rattus norvegicus 15377 R-RNO-74258 https://reactome.org/PathwayBrowser/#/R-RNO-74258 XDH oxidizes xanthine to form urate IEA Rattus norvegicus 15377 R-RNO-74733 https://reactome.org/PathwayBrowser/#/R-RNO-74733 Insulin receptor de-phosphorylation IEA Rattus norvegicus 15377 R-RNO-74948 https://reactome.org/PathwayBrowser/#/R-RNO-74948 PP2A dephosphorylates p-RHO to RHO IEA Rattus norvegicus 15377 R-RNO-75872 https://reactome.org/PathwayBrowser/#/R-RNO-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Rattus norvegicus 15377 R-RNO-75899 https://reactome.org/PathwayBrowser/#/R-RNO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Rattus norvegicus 15377 R-RNO-76031 https://reactome.org/PathwayBrowser/#/R-RNO-76031 2 H2O2 => O2 + 2 H2O IEA Rattus norvegicus 15377 R-RNO-76354 https://reactome.org/PathwayBrowser/#/R-RNO-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Rattus norvegicus 15377 R-RNO-76373 https://reactome.org/PathwayBrowser/#/R-RNO-76373 N-hydroxylation of 4-aminobiphenyl IEA Rattus norvegicus 15377 R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 15377 R-RNO-76397 https://reactome.org/PathwayBrowser/#/R-RNO-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Rattus norvegicus 15377 R-RNO-76416 https://reactome.org/PathwayBrowser/#/R-RNO-76416 Benzene is hydroxylated to phenol IEA Rattus norvegicus 15377 R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 15377 R-RNO-76453 https://reactome.org/PathwayBrowser/#/R-RNO-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Rattus norvegicus 15377 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 15377 R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 15377 R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 15377 R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 15377 R-RNO-76590 https://reactome.org/PathwayBrowser/#/R-RNO-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Rattus norvegicus 15377 R-RNO-77256 https://reactome.org/PathwayBrowser/#/R-RNO-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-77277 https://reactome.org/PathwayBrowser/#/R-RNO-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-77301 https://reactome.org/PathwayBrowser/#/R-RNO-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-77314 https://reactome.org/PathwayBrowser/#/R-RNO-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-77325 https://reactome.org/PathwayBrowser/#/R-RNO-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-77333 https://reactome.org/PathwayBrowser/#/R-RNO-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-77344 https://reactome.org/PathwayBrowser/#/R-RNO-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Rattus norvegicus 15377 R-RNO-77614 https://reactome.org/PathwayBrowser/#/R-RNO-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Rattus norvegicus 15377 R-RNO-77615 https://reactome.org/PathwayBrowser/#/R-RNO-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Rattus norvegicus 15377 R-RNO-83677 https://reactome.org/PathwayBrowser/#/R-RNO-83677 C4 deamination of cytidine IEA Rattus norvegicus 15377 R-RNO-8848053 https://reactome.org/PathwayBrowser/#/R-RNO-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Rattus norvegicus 15377 R-RNO-8848215 https://reactome.org/PathwayBrowser/#/R-RNO-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Rattus norvegicus 15377 R-RNO-8848338 https://reactome.org/PathwayBrowser/#/R-RNO-8848338 PNPLA4 hydrolyzes TAG IEA Rattus norvegicus 15377 R-RNO-8848339 https://reactome.org/PathwayBrowser/#/R-RNO-8848339 PNPLA5 hydrolyzes TAG IEA Rattus norvegicus 15377 R-RNO-8848355 https://reactome.org/PathwayBrowser/#/R-RNO-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Rattus norvegicus 15377 R-RNO-8848484 https://reactome.org/PathwayBrowser/#/R-RNO-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Rattus norvegicus 15377 R-RNO-8849435 https://reactome.org/PathwayBrowser/#/R-RNO-8849435 PTPN1 dephosphorylates PTK6 IEA Rattus norvegicus 15377 R-RNO-8849857 https://reactome.org/PathwayBrowser/#/R-RNO-8849857 KLK5 cleaves and activates CELA2 IEA Rattus norvegicus 15377 R-RNO-8849969 https://reactome.org/PathwayBrowser/#/R-RNO-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Rattus norvegicus 15377 R-RNO-8850594 https://reactome.org/PathwayBrowser/#/R-RNO-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Rattus norvegicus 15377 R-RNO-8850831 https://reactome.org/PathwayBrowser/#/R-RNO-8850831 KLK5 cleaves and activates KLK8 IEA Rattus norvegicus 15377 R-RNO-8850846 https://reactome.org/PathwayBrowser/#/R-RNO-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-RNO-8850854 https://reactome.org/PathwayBrowser/#/R-RNO-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-RNO-8851110 https://reactome.org/PathwayBrowser/#/R-RNO-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-RNO-8851129 https://reactome.org/PathwayBrowser/#/R-RNO-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-RNO-8852200 https://reactome.org/PathwayBrowser/#/R-RNO-8852200 Inactivation of LCK by PTPN22 IEA Rattus norvegicus 15377 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 15377 R-RNO-8853686 https://reactome.org/PathwayBrowser/#/R-RNO-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Rattus norvegicus 15377 R-RNO-8854173 https://reactome.org/PathwayBrowser/#/R-RNO-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Rattus norvegicus 15377 R-RNO-8854255 https://reactome.org/PathwayBrowser/#/R-RNO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 15377 R-RNO-8854329 https://reactome.org/PathwayBrowser/#/R-RNO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 15377 R-RNO-8854604 https://reactome.org/PathwayBrowser/#/R-RNO-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Rattus norvegicus 15377 R-RNO-8854612 https://reactome.org/PathwayBrowser/#/R-RNO-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Rattus norvegicus 15377 R-RNO-8855381 https://reactome.org/PathwayBrowser/#/R-RNO-8855381 PTPN22 dephosphorylates ZAP70 IEA Rattus norvegicus 15377 R-RNO-8855490 https://reactome.org/PathwayBrowser/#/R-RNO-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Rattus norvegicus 15377 R-RNO-8855825 https://reactome.org/PathwayBrowser/#/R-RNO-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Rattus norvegicus 15377 R-RNO-8856951 https://reactome.org/PathwayBrowser/#/R-RNO-8856951 PP2A demethylation by PPME1 IEA Rattus norvegicus 15377 R-RNO-8862184 https://reactome.org/PathwayBrowser/#/R-RNO-8862184 USP48 cleaves polyubiquitin IEA Rattus norvegicus 15377 R-RNO-8862320 https://reactome.org/PathwayBrowser/#/R-RNO-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Rattus norvegicus 15377 R-RNO-8863804 https://reactome.org/PathwayBrowser/#/R-RNO-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Rattus norvegicus 15377 R-RNO-8864029 https://reactome.org/PathwayBrowser/#/R-RNO-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Rattus norvegicus 15377 R-RNO-8864036 https://reactome.org/PathwayBrowser/#/R-RNO-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Rattus norvegicus 15377 R-RNO-8864125 https://reactome.org/PathwayBrowser/#/R-RNO-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Rattus norvegicus 15377 R-RNO-8865667 https://reactome.org/PathwayBrowser/#/R-RNO-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Rattus norvegicus 15377 R-RNO-8866405 https://reactome.org/PathwayBrowser/#/R-RNO-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 15377 R-RNO-8866542 https://reactome.org/PathwayBrowser/#/R-RNO-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Rattus norvegicus 15377 R-RNO-8866601 https://reactome.org/PathwayBrowser/#/R-RNO-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Rattus norvegicus 15377 R-RNO-8867047 https://reactome.org/PathwayBrowser/#/R-RNO-8867047 PTPN3 dephosphorylates EPS15 IEA Rattus norvegicus 15377 R-RNO-8867344 https://reactome.org/PathwayBrowser/#/R-RNO-8867344 OMA1 hydrolyses OPA1 IEA Rattus norvegicus 15377 R-RNO-8867658 https://reactome.org/PathwayBrowser/#/R-RNO-8867658 PTPN3 dephosphorylates MAPK12 IEA Rattus norvegicus 15377 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 15377 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 15377 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 15377 R-RNO-8869206 https://reactome.org/PathwayBrowser/#/R-RNO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Rattus norvegicus 15377 R-RNO-8869425 https://reactome.org/PathwayBrowser/#/R-RNO-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Rattus norvegicus 15377 R-RNO-8869456 https://reactome.org/PathwayBrowser/#/R-RNO-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Rattus norvegicus 15377 R-RNO-8869506 https://reactome.org/PathwayBrowser/#/R-RNO-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Rattus norvegicus 15377 R-RNO-8870346 https://reactome.org/PathwayBrowser/#/R-RNO-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Rattus norvegicus 15377 R-RNO-8874435 https://reactome.org/PathwayBrowser/#/R-RNO-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Rattus norvegicus 15377 R-RNO-8875443 https://reactome.org/PathwayBrowser/#/R-RNO-8875443 USP8 deubiquitinates LRIG1 IEA Rattus norvegicus 15377 R-RNO-8878581 https://reactome.org/PathwayBrowser/#/R-RNO-8878581 TYRP1 oxidises DHICA to IQCA IEA Rattus norvegicus 15377 R-RNO-8878654 https://reactome.org/PathwayBrowser/#/R-RNO-8878654 ACP6 hydrolyses MYS-LPA IEA Rattus norvegicus 15377 R-RNO-8878787 https://reactome.org/PathwayBrowser/#/R-RNO-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Rattus norvegicus 15377 R-RNO-888548 https://reactome.org/PathwayBrowser/#/R-RNO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Rattus norvegicus 15377 R-RNO-8932633 https://reactome.org/PathwayBrowser/#/R-RNO-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Rattus norvegicus 15377 R-RNO-8933328 https://reactome.org/PathwayBrowser/#/R-RNO-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Rattus norvegicus 15377 R-RNO-8933635 https://reactome.org/PathwayBrowser/#/R-RNO-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Rattus norvegicus 15377 R-RNO-8936442 https://reactome.org/PathwayBrowser/#/R-RNO-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Rattus norvegicus 15377 R-RNO-8937767 https://reactome.org/PathwayBrowser/#/R-RNO-8937767 PTPN11 dephosphorylates RUNX1 IEA Rattus norvegicus 15377 R-RNO-8938076 https://reactome.org/PathwayBrowser/#/R-RNO-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Rattus norvegicus 15377 R-RNO-8940070 https://reactome.org/PathwayBrowser/#/R-RNO-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Rattus norvegicus 15377 R-RNO-8940074 https://reactome.org/PathwayBrowser/#/R-RNO-8940074 NT5E:Zn2+ hydrolyses NMN IEA Rattus norvegicus 15377 R-RNO-8940388 https://reactome.org/PathwayBrowser/#/R-RNO-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Rattus norvegicus 15377 R-RNO-8943279 https://reactome.org/PathwayBrowser/#/R-RNO-8943279 GGT dimers hydrolyse GSH IEA Rattus norvegicus 15377 R-RNO-8952137 https://reactome.org/PathwayBrowser/#/R-RNO-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Rattus norvegicus 15377 R-RNO-8952251 https://reactome.org/PathwayBrowser/#/R-RNO-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Rattus norvegicus 15377 R-RNO-8952903 https://reactome.org/PathwayBrowser/#/R-RNO-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Rattus norvegicus 15377 R-RNO-8953339 https://reactome.org/PathwayBrowser/#/R-RNO-8953339 DNPH1 hydrolyses dGMP IEA Rattus norvegicus 15377 R-RNO-8953499 https://reactome.org/PathwayBrowser/#/R-RNO-8953499 IMPAD1 hydrolyses PAP to AMP IEA Rattus norvegicus 15377 R-RNO-8954398 https://reactome.org/PathwayBrowser/#/R-RNO-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Rattus norvegicus 15377 R-RNO-8955775 https://reactome.org/PathwayBrowser/#/R-RNO-8955775 Pgp:Mg2+ dimer hydrolyses 3PG to glycerol TAS Rattus norvegicus 15377 R-RNO-8955817 https://reactome.org/PathwayBrowser/#/R-RNO-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Rattus norvegicus 15377 R-RNO-8957389 https://reactome.org/PathwayBrowser/#/R-RNO-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Rattus norvegicus 15377 R-RNO-8959510 https://reactome.org/PathwayBrowser/#/R-RNO-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Rattus norvegicus 15377 R-RNO-8979996 https://reactome.org/PathwayBrowser/#/R-RNO-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Rattus norvegicus 15377 R-RNO-8980228 https://reactome.org/PathwayBrowser/#/R-RNO-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Rattus norvegicus 15377 R-RNO-8981637 https://reactome.org/PathwayBrowser/#/R-RNO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Rattus norvegicus 15377 R-RNO-8985594 https://reactome.org/PathwayBrowser/#/R-RNO-8985594 MYO9B inactivates RHOA IEA Rattus norvegicus 15377 R-RNO-9009950 https://reactome.org/PathwayBrowser/#/R-RNO-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Rattus norvegicus 15377 R-RNO-9013022 https://reactome.org/PathwayBrowser/#/R-RNO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Rattus norvegicus 15377 R-RNO-9013144 https://reactome.org/PathwayBrowser/#/R-RNO-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Rattus norvegicus 15377 R-RNO-9013161 https://reactome.org/PathwayBrowser/#/R-RNO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Rattus norvegicus 15377 R-RNO-9013437 https://reactome.org/PathwayBrowser/#/R-RNO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Rattus norvegicus 15377 R-RNO-9014295 https://reactome.org/PathwayBrowser/#/R-RNO-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Rattus norvegicus 15377 R-RNO-9014434 https://reactome.org/PathwayBrowser/#/R-RNO-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Rattus norvegicus 15377 R-RNO-9014627 https://reactome.org/PathwayBrowser/#/R-RNO-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Rattus norvegicus 15377 R-RNO-9014741 https://reactome.org/PathwayBrowser/#/R-RNO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Rattus norvegicus 15377 R-RNO-9017488 https://reactome.org/PathwayBrowser/#/R-RNO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Rattus norvegicus 15377 R-RNO-9018745 https://reactome.org/PathwayBrowser/#/R-RNO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Rattus norvegicus 15377 R-RNO-9018826 https://reactome.org/PathwayBrowser/#/R-RNO-9018826 RHOT2 hydrolyzes GTP IEA Rattus norvegicus 15377 R-RNO-9018862 https://reactome.org/PathwayBrowser/#/R-RNO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Rattus norvegicus 15377 R-RNO-9018868 https://reactome.org/PathwayBrowser/#/R-RNO-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Rattus norvegicus 15377 R-RNO-9018877 https://reactome.org/PathwayBrowser/#/R-RNO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Rattus norvegicus 15377 R-RNO-9018895 https://reactome.org/PathwayBrowser/#/R-RNO-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Rattus norvegicus 15377 R-RNO-9020252 https://reactome.org/PathwayBrowser/#/R-RNO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Rattus norvegicus 15377 R-RNO-9020253 https://reactome.org/PathwayBrowser/#/R-RNO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Rattus norvegicus 15377 R-RNO-9020257 https://reactome.org/PathwayBrowser/#/R-RNO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Rattus norvegicus 15377 R-RNO-9020258 https://reactome.org/PathwayBrowser/#/R-RNO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Rattus norvegicus 15377 R-RNO-9020270 https://reactome.org/PathwayBrowser/#/R-RNO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Rattus norvegicus 15377 R-RNO-9020271 https://reactome.org/PathwayBrowser/#/R-RNO-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Rattus norvegicus 15377 R-RNO-9020273 https://reactome.org/PathwayBrowser/#/R-RNO-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Rattus norvegicus 15377 R-RNO-9024890 https://reactome.org/PathwayBrowser/#/R-RNO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Rattus norvegicus 15377 R-RNO-9027043 https://reactome.org/PathwayBrowser/#/R-RNO-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Rattus norvegicus 15377 R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 15377 R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 15377 R-RNO-9033520 https://reactome.org/PathwayBrowser/#/R-RNO-9033520 TYSND1 cleaves TYSND1 IEA Rattus norvegicus 15377 R-RNO-9034539 https://reactome.org/PathwayBrowser/#/R-RNO-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Rattus norvegicus 15377 R-RNO-9036727 https://reactome.org/PathwayBrowser/#/R-RNO-9036727 GAA hydrolyzes lysosomal glycogen IEA Rattus norvegicus 15377 R-RNO-9037761 https://reactome.org/PathwayBrowser/#/R-RNO-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Rattus norvegicus 15377 R-RNO-917841 https://reactome.org/PathwayBrowser/#/R-RNO-917841 Acidification of Tf:TfR1 containing endosome IEA Rattus norvegicus 15377 R-RNO-917891 https://reactome.org/PathwayBrowser/#/R-RNO-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Rattus norvegicus 15377 R-RNO-917933 https://reactome.org/PathwayBrowser/#/R-RNO-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Rattus norvegicus 15377 R-RNO-917979 https://reactome.org/PathwayBrowser/#/R-RNO-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Rattus norvegicus 15377 R-RNO-936802 https://reactome.org/PathwayBrowser/#/R-RNO-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Rattus norvegicus 15377 R-RNO-936883 https://reactome.org/PathwayBrowser/#/R-RNO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Rattus norvegicus 15377 R-RNO-936895 https://reactome.org/PathwayBrowser/#/R-RNO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Rattus norvegicus 15377 R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 15377 R-RNO-937311 https://reactome.org/PathwayBrowser/#/R-RNO-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 15377 R-RNO-939763 https://reactome.org/PathwayBrowser/#/R-RNO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Rattus norvegicus 15377 R-RNO-947531 https://reactome.org/PathwayBrowser/#/R-RNO-947531 Molybdenum ion transfer onto molybdopterin IEA Rattus norvegicus 15377 R-RNO-947535 https://reactome.org/PathwayBrowser/#/R-RNO-947535 Cyclisation of GTP to precursor Z IEA Rattus norvegicus 15377 R-RNO-947591 https://reactome.org/PathwayBrowser/#/R-RNO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Rattus norvegicus 15377 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 15377 R-RNO-9619441 https://reactome.org/PathwayBrowser/#/R-RNO-9619441 Ppm1e dephosphorylates Camk4 TAS Rattus norvegicus 15377 R-RNO-9619459 https://reactome.org/PathwayBrowser/#/R-RNO-9619459 Ppm1f dephosphorylates p-T286-CaMKII-alpha TAS Rattus norvegicus 15377 R-RNO-9619472 https://reactome.org/PathwayBrowser/#/R-RNO-9619472 Ppm1f dephosphorylates Camk1 TAS Rattus norvegicus 15377 R-RNO-9620103 https://reactome.org/PathwayBrowser/#/R-RNO-9620103 ALDH2 transforms GTN to NO IEA Rattus norvegicus 15377 R-RNO-9624893 https://reactome.org/PathwayBrowser/#/R-RNO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Rattus norvegicus 15377 R-RNO-9629675 https://reactome.org/PathwayBrowser/#/R-RNO-9629675 PDE3A hydrolyses cAMP to AMP IEA Rattus norvegicus 15377 R-RNO-9635739 https://reactome.org/PathwayBrowser/#/R-RNO-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Rattus norvegicus 15377 R-RNO-9638046 https://reactome.org/PathwayBrowser/#/R-RNO-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 15377 R-RNO-9638075 https://reactome.org/PathwayBrowser/#/R-RNO-9638075 HEXB cleaves the terminal GalNAc from DS IEA Rattus norvegicus 15377 R-RNO-9638076 https://reactome.org/PathwayBrowser/#/R-RNO-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Rattus norvegicus 15377 R-RNO-9638078 https://reactome.org/PathwayBrowser/#/R-RNO-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Rattus norvegicus 15377 R-RNO-9638120 https://reactome.org/PathwayBrowser/#/R-RNO-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 15377 R-RNO-9644869 https://reactome.org/PathwayBrowser/#/R-RNO-9644869 p-S54-PDE4B hydrolyses cAMP IEA Rattus norvegicus 15377 R-RNO-9647994 https://reactome.org/PathwayBrowser/#/R-RNO-9647994 RAS proteins are depalmitoylated IEA Rattus norvegicus 15377 R-RNO-965067 https://reactome.org/PathwayBrowser/#/R-RNO-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Rattus norvegicus 15377 R-RNO-965079 https://reactome.org/PathwayBrowser/#/R-RNO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Rattus norvegicus 15377 R-RNO-9653514 https://reactome.org/PathwayBrowser/#/R-RNO-9653514 USP17L2 deubiquitinates RCE1 IEA Rattus norvegicus 15377 R-RNO-9656891 https://reactome.org/PathwayBrowser/#/R-RNO-9656891 OPN1SW binds 11cRAL IEA Rattus norvegicus 15377 R-RNO-9656893 https://reactome.org/PathwayBrowser/#/R-RNO-9656893 OPN1MW binds 11cRAL IEA Rattus norvegicus 15377 R-RNO-9658445 https://reactome.org/PathwayBrowser/#/R-RNO-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Rattus norvegicus 15377 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 15377 R-RNO-9661417 https://reactome.org/PathwayBrowser/#/R-RNO-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 15377 R-RNO-9667952 https://reactome.org/PathwayBrowser/#/R-RNO-9667952 ANKLE2 is deacetylated by SIRT2 IEA Rattus norvegicus 15377 R-RNO-9668419 https://reactome.org/PathwayBrowser/#/R-RNO-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Rattus norvegicus 15377 R-RNO-9673053 https://reactome.org/PathwayBrowser/#/R-RNO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Rattus norvegicus 15377 R-RNO-9673054 https://reactome.org/PathwayBrowser/#/R-RNO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Rattus norvegicus 15377 R-RNO-9674127 https://reactome.org/PathwayBrowser/#/R-RNO-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Rattus norvegicus 15377 R-RNO-9686524 https://reactome.org/PathwayBrowser/#/R-RNO-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Rattus norvegicus 15377 R-RNO-9693282 https://reactome.org/PathwayBrowser/#/R-RNO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Rattus norvegicus 15377 R-RNO-9700200 https://reactome.org/PathwayBrowser/#/R-RNO-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Rattus norvegicus 15377 R-RNO-9701507 https://reactome.org/PathwayBrowser/#/R-RNO-9701507 PTPN6 dephosphorylates JAK3 IEA Rattus norvegicus 15377 R-RNO-9701565 https://reactome.org/PathwayBrowser/#/R-RNO-9701565 HDACs deacetylate p-STAT3 dimers IEA Rattus norvegicus 15377 R-RNO-9705507 https://reactome.org/PathwayBrowser/#/R-RNO-9705507 PDE3B hydrolyses cAMP to AMP IEA Rattus norvegicus 15377 R-RNO-9706399 https://reactome.org/PathwayBrowser/#/R-RNO-9706399 RHOBTB3 hydrolyzes ATP IEA Rattus norvegicus 15377 R-RNO-9708261 https://reactome.org/PathwayBrowser/#/R-RNO-9708261 PDE4A hydrolyses cAMP to AMP IEA Rattus norvegicus 15377 R-RNO-9709360 https://reactome.org/PathwayBrowser/#/R-RNO-9709360 H2O2 reduces MetHb IEA Rattus norvegicus 15377 R-RNO-9727198 https://reactome.org/PathwayBrowser/#/R-RNO-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 15377 R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 15377 R-RNO-9727349 https://reactome.org/PathwayBrowser/#/R-RNO-9727349 XDH dehydrogenates xanthine to form urate IEA Rattus norvegicus 15377 R-RNO-9727567 https://reactome.org/PathwayBrowser/#/R-RNO-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Rattus norvegicus 15377 R-RNO-9731228 https://reactome.org/PathwayBrowser/#/R-RNO-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Rattus norvegicus 15377 R-RNO-9731590 https://reactome.org/PathwayBrowser/#/R-RNO-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Rattus norvegicus 15377 R-RNO-9731613 https://reactome.org/PathwayBrowser/#/R-RNO-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Rattus norvegicus 15377 R-RNO-9731632 https://reactome.org/PathwayBrowser/#/R-RNO-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Rattus norvegicus 15377 R-RNO-9748945 https://reactome.org/PathwayBrowser/#/R-RNO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Rattus norvegicus 15377 R-RNO-9748957 https://reactome.org/PathwayBrowser/#/R-RNO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Rattus norvegicus 15377 R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 15377 R-RNO-9749609 https://reactome.org/PathwayBrowser/#/R-RNO-9749609 BCHE hydrolyzes ASA- IEA Rattus norvegicus 15377 R-RNO-9749647 https://reactome.org/PathwayBrowser/#/R-RNO-9749647 CES2 hydrolyzes ASA- IEA Rattus norvegicus 15377 R-RNO-9749792 https://reactome.org/PathwayBrowser/#/R-RNO-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Rattus norvegicus 15377 R-RNO-9749986 https://reactome.org/PathwayBrowser/#/R-RNO-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Rattus norvegicus 15377 R-RNO-9750016 https://reactome.org/PathwayBrowser/#/R-RNO-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Rattus norvegicus 15377 R-RNO-9750546 https://reactome.org/PathwayBrowser/#/R-RNO-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 15377 R-RNO-9750555 https://reactome.org/PathwayBrowser/#/R-RNO-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Rattus norvegicus 15377 R-RNO-9750617 https://reactome.org/PathwayBrowser/#/R-RNO-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 15377 R-RNO-9750656 https://reactome.org/PathwayBrowser/#/R-RNO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Rattus norvegicus 15377 R-RNO-9750942 https://reactome.org/PathwayBrowser/#/R-RNO-9750942 USP14 deubiquitinates NLRC5 IEA Rattus norvegicus 15377 R-RNO-9753278 https://reactome.org/PathwayBrowser/#/R-RNO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 15377 R-RNO-9753280 https://reactome.org/PathwayBrowser/#/R-RNO-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Rattus norvegicus 15377 R-RNO-9753283 https://reactome.org/PathwayBrowser/#/R-RNO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 15377 R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 15377 R-RNO-9753285 https://reactome.org/PathwayBrowser/#/R-RNO-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Rattus norvegicus 15377 R-RNO-9753632 https://reactome.org/PathwayBrowser/#/R-RNO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Rattus norvegicus 15377 R-RNO-9753634 https://reactome.org/PathwayBrowser/#/R-RNO-9753634 GGT dimers hydrolyse APAP-SG IEA Rattus norvegicus 15377 R-RNO-9753944 https://reactome.org/PathwayBrowser/#/R-RNO-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Rattus norvegicus 15377 R-RNO-9754964 https://reactome.org/PathwayBrowser/#/R-RNO-9754964 ADA deamidates RBV IEA Rattus norvegicus 15377 R-RNO-9755030 https://reactome.org/PathwayBrowser/#/R-RNO-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Rattus norvegicus 15377 R-RNO-9755078 https://reactome.org/PathwayBrowser/#/R-RNO-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Rattus norvegicus 15377 R-RNO-975593 https://reactome.org/PathwayBrowser/#/R-RNO-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Rattus norvegicus 15377 R-RNO-975594 https://reactome.org/PathwayBrowser/#/R-RNO-975594 PLB1 hydrolyses RPALM to atROL IEA Rattus norvegicus 15377 R-RNO-9756138 https://reactome.org/PathwayBrowser/#/R-RNO-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Rattus norvegicus 15377 R-RNO-9756162 https://reactome.org/PathwayBrowser/#/R-RNO-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Rattus norvegicus 15377 R-RNO-9756169 https://reactome.org/PathwayBrowser/#/R-RNO-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Rattus norvegicus 15377 R-RNO-9756177 https://reactome.org/PathwayBrowser/#/R-RNO-9756177 PON1,3 hydrolyse ATVL to ATV IEA Rattus norvegicus 15377 R-RNO-9756180 https://reactome.org/PathwayBrowser/#/R-RNO-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Rattus norvegicus 15377 R-RNO-9758674 https://reactome.org/PathwayBrowser/#/R-RNO-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Rattus norvegicus 15377 R-RNO-9759454 https://reactome.org/PathwayBrowser/#/R-RNO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Rattus norvegicus 15377 R-RNO-9759461 https://reactome.org/PathwayBrowser/#/R-RNO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Rattus norvegicus 15377 R-RNO-977324 https://reactome.org/PathwayBrowser/#/R-RNO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Rattus norvegicus 15377 R-RNO-9794120 https://reactome.org/PathwayBrowser/#/R-RNO-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Rattus norvegicus 15377 R-RNO-9794572 https://reactome.org/PathwayBrowser/#/R-RNO-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Rattus norvegicus 15377 R-RNO-983144 https://reactome.org/PathwayBrowser/#/R-RNO-983144 Transport of Antigen peptide in to ER IEA Rattus norvegicus 15377 R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus 15377 R-RNO-9837419 https://reactome.org/PathwayBrowser/#/R-RNO-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Rattus norvegicus 15377 R-RNO-9838004 https://reactome.org/PathwayBrowser/#/R-RNO-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Rattus norvegicus 15377 R-RNO-9838081 https://reactome.org/PathwayBrowser/#/R-RNO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Rattus norvegicus 15377 R-RNO-9838289 https://reactome.org/PathwayBrowser/#/R-RNO-9838289 CLPXP degrades mitochondrial matrix proteins IEA Rattus norvegicus 15377 R-RNO-9839059 https://reactome.org/PathwayBrowser/#/R-RNO-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Rattus norvegicus 15377 R-RNO-9839072 https://reactome.org/PathwayBrowser/#/R-RNO-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Rattus norvegicus 15377 R-RNO-9839105 https://reactome.org/PathwayBrowser/#/R-RNO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Rattus norvegicus 15377 R-RNO-9839110 https://reactome.org/PathwayBrowser/#/R-RNO-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Rattus norvegicus 15377 R-RNO-9839113 https://reactome.org/PathwayBrowser/#/R-RNO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Rattus norvegicus 15377 R-RNO-9840408 https://reactome.org/PathwayBrowser/#/R-RNO-9840408 OMA1 cleaves DELE1 IEA Rattus norvegicus 15377 R-RNO-9840795 https://reactome.org/PathwayBrowser/#/R-RNO-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Rattus norvegicus 15377 R-RNO-9840833 https://reactome.org/PathwayBrowser/#/R-RNO-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Rattus norvegicus 15377 R-RNO-9840884 https://reactome.org/PathwayBrowser/#/R-RNO-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Rattus norvegicus 15377 R-RNO-9840949 https://reactome.org/PathwayBrowser/#/R-RNO-9840949 ARSA removes sulfate from SM3 IEA Rattus norvegicus 15377 R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 15377 R-RNO-9843721 https://reactome.org/PathwayBrowser/#/R-RNO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Rattus norvegicus 15377 R-RNO-9853385 https://reactome.org/PathwayBrowser/#/R-RNO-9853385 PPP1CC dephosphorylates PLK1 IEA Rattus norvegicus 15377 R-RNO-9861626 https://reactome.org/PathwayBrowser/#/R-RNO-9861626 SIRT4 cleaves lipoyl from DLAT IEA Rattus norvegicus 15377 R-RNO-9861725 https://reactome.org/PathwayBrowser/#/R-RNO-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Rattus norvegicus 15377 R-RNO-997309 https://reactome.org/PathwayBrowser/#/R-RNO-997309 Dephosphorylation of STAT1 by SHP2 IEA Rattus norvegicus 15377 R-RNO-997311 https://reactome.org/PathwayBrowser/#/R-RNO-997311 Dephosphorylation of TYK2 by PTP1B IEA Rattus norvegicus 15377 R-RNO-997314 https://reactome.org/PathwayBrowser/#/R-RNO-997314 Dephosphorylation of JAK1 by SHP1 IEA Rattus norvegicus 15377 R-RNO-997326 https://reactome.org/PathwayBrowser/#/R-RNO-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Rattus norvegicus 15377 R-SCE-111751 https://reactome.org/PathwayBrowser/#/R-SCE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 15377 R-SCE-111804 https://reactome.org/PathwayBrowser/#/R-SCE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 15377 R-SCE-111879 https://reactome.org/PathwayBrowser/#/R-SCE-111879 PIP2 hydrolysis IEA Saccharomyces cerevisiae 15377 R-SCE-111883 https://reactome.org/PathwayBrowser/#/R-SCE-111883 Hydrolysis of phosphatidylcholine IEA Saccharomyces cerevisiae 15377 R-SCE-112037 https://reactome.org/PathwayBrowser/#/R-SCE-112037 Inactivation of PLC beta IEA Saccharomyces cerevisiae 15377 R-SCE-1237121 https://reactome.org/PathwayBrowser/#/R-SCE-1237121 Dehydration of methylthio-ribulose-P TAS Saccharomyces cerevisiae 15377 R-SCE-1237129 https://reactome.org/PathwayBrowser/#/R-SCE-1237129 Acireductone is created IEA Saccharomyces cerevisiae 15377 R-SCE-1247910 https://reactome.org/PathwayBrowser/#/R-SCE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Saccharomyces cerevisiae 15377 R-SCE-1247935 https://reactome.org/PathwayBrowser/#/R-SCE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Saccharomyces cerevisiae 15377 R-SCE-1454916 https://reactome.org/PathwayBrowser/#/R-SCE-1454916 The ABCC family mediates organic anion transport IEA Saccharomyces cerevisiae 15377 R-SCE-1454928 https://reactome.org/PathwayBrowser/#/R-SCE-1454928 ABCG4 may mediate cholesterol efflux IEA Saccharomyces cerevisiae 15377 R-SCE-1474146 https://reactome.org/PathwayBrowser/#/R-SCE-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Saccharomyces cerevisiae 15377 R-SCE-1482543 https://reactome.org/PathwayBrowser/#/R-SCE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Saccharomyces cerevisiae 15377 R-SCE-1482545 https://reactome.org/PathwayBrowser/#/R-SCE-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-SCE-1482571 https://reactome.org/PathwayBrowser/#/R-SCE-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-SCE-1482604 https://reactome.org/PathwayBrowser/#/R-SCE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Saccharomyces cerevisiae 15377 R-SCE-1482612 https://reactome.org/PathwayBrowser/#/R-SCE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 15377 R-SCE-1482629 https://reactome.org/PathwayBrowser/#/R-SCE-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-SCE-1482656 https://reactome.org/PathwayBrowser/#/R-SCE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Saccharomyces cerevisiae 15377 R-SCE-1482685 https://reactome.org/PathwayBrowser/#/R-SCE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 15377 R-SCE-1482696 https://reactome.org/PathwayBrowser/#/R-SCE-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-SCE-1482745 https://reactome.org/PathwayBrowser/#/R-SCE-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Saccharomyces cerevisiae 15377 R-SCE-1482759 https://reactome.org/PathwayBrowser/#/R-SCE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Saccharomyces cerevisiae 15377 R-SCE-1482771 https://reactome.org/PathwayBrowser/#/R-SCE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Saccharomyces cerevisiae 15377 R-SCE-1482816 https://reactome.org/PathwayBrowser/#/R-SCE-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Saccharomyces cerevisiae 15377 R-SCE-1482825 https://reactome.org/PathwayBrowser/#/R-SCE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Saccharomyces cerevisiae 15377 R-SCE-1482827 https://reactome.org/PathwayBrowser/#/R-SCE-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-SCE-1482828 https://reactome.org/PathwayBrowser/#/R-SCE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Saccharomyces cerevisiae 15377 R-SCE-1482847 https://reactome.org/PathwayBrowser/#/R-SCE-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Saccharomyces cerevisiae 15377 R-SCE-1482856 https://reactome.org/PathwayBrowser/#/R-SCE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Saccharomyces cerevisiae 15377 R-SCE-1482862 https://reactome.org/PathwayBrowser/#/R-SCE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Saccharomyces cerevisiae 15377 R-SCE-1482868 https://reactome.org/PathwayBrowser/#/R-SCE-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Saccharomyces cerevisiae 15377 R-SCE-1482884 https://reactome.org/PathwayBrowser/#/R-SCE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Saccharomyces cerevisiae 15377 R-SCE-1482892 https://reactome.org/PathwayBrowser/#/R-SCE-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-SCE-1482897 https://reactome.org/PathwayBrowser/#/R-SCE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Saccharomyces cerevisiae 15377 R-SCE-1482900 https://reactome.org/PathwayBrowser/#/R-SCE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Saccharomyces cerevisiae 15377 R-SCE-1482920 https://reactome.org/PathwayBrowser/#/R-SCE-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Saccharomyces cerevisiae 15377 R-SCE-1482932 https://reactome.org/PathwayBrowser/#/R-SCE-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Saccharomyces cerevisiae 15377 R-SCE-1483182 https://reactome.org/PathwayBrowser/#/R-SCE-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Saccharomyces cerevisiae 15377 R-SCE-1483203 https://reactome.org/PathwayBrowser/#/R-SCE-1483203 PA is dephosphorylated to DAG by LPIN IEA Saccharomyces cerevisiae 15377 R-SCE-159425 https://reactome.org/PathwayBrowser/#/R-SCE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 15377 R-SCE-1606273 https://reactome.org/PathwayBrowser/#/R-SCE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Saccharomyces cerevisiae 15377 R-SCE-1614524 https://reactome.org/PathwayBrowser/#/R-SCE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Saccharomyces cerevisiae 15377 R-SCE-1614583 https://reactome.org/PathwayBrowser/#/R-SCE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Saccharomyces cerevisiae 15377 R-SCE-1614614 https://reactome.org/PathwayBrowser/#/R-SCE-1614614 Cysteine is degraded to serine and H2S IEA Saccharomyces cerevisiae 15377 R-SCE-1614631 https://reactome.org/PathwayBrowser/#/R-SCE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Saccharomyces cerevisiae 15377 R-SCE-162857 https://reactome.org/PathwayBrowser/#/R-SCE-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Saccharomyces cerevisiae 15377 R-SCE-1640164 https://reactome.org/PathwayBrowser/#/R-SCE-1640164 ENPP7 hydrolyzes sphingomyelin IEA Saccharomyces cerevisiae 15377 R-SCE-164832 https://reactome.org/PathwayBrowser/#/R-SCE-164832 ATPase synthesizes ATP IEA Saccharomyces cerevisiae 15377 R-SCE-1675795 https://reactome.org/PathwayBrowser/#/R-SCE-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1675836 https://reactome.org/PathwayBrowser/#/R-SCE-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1675949 https://reactome.org/PathwayBrowser/#/R-SCE-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1675988 https://reactome.org/PathwayBrowser/#/R-SCE-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1675994 https://reactome.org/PathwayBrowser/#/R-SCE-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1676065 https://reactome.org/PathwayBrowser/#/R-SCE-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1676105 https://reactome.org/PathwayBrowser/#/R-SCE-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1676114 https://reactome.org/PathwayBrowser/#/R-SCE-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1676124 https://reactome.org/PathwayBrowser/#/R-SCE-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1676141 https://reactome.org/PathwayBrowser/#/R-SCE-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1676149 https://reactome.org/PathwayBrowser/#/R-SCE-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1676177 https://reactome.org/PathwayBrowser/#/R-SCE-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1676203 https://reactome.org/PathwayBrowser/#/R-SCE-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1676204 https://reactome.org/PathwayBrowser/#/R-SCE-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Saccharomyces cerevisiae 15377 R-SCE-174124 https://reactome.org/PathwayBrowser/#/R-SCE-174124 Dephosphorylation of phospho-Cdh1 IEA Saccharomyces cerevisiae 15377 R-SCE-174391 https://reactome.org/PathwayBrowser/#/R-SCE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Saccharomyces cerevisiae 15377 R-SCE-174401 https://reactome.org/PathwayBrowser/#/R-SCE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Saccharomyces cerevisiae 15377 R-SCE-1855154 https://reactome.org/PathwayBrowser/#/R-SCE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-1855165 https://reactome.org/PathwayBrowser/#/R-SCE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-1855166 https://reactome.org/PathwayBrowser/#/R-SCE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-1855174 https://reactome.org/PathwayBrowser/#/R-SCE-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-1855177 https://reactome.org/PathwayBrowser/#/R-SCE-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1855198 https://reactome.org/PathwayBrowser/#/R-SCE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-1855205 https://reactome.org/PathwayBrowser/#/R-SCE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-1855210 https://reactome.org/PathwayBrowser/#/R-SCE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-1855211 https://reactome.org/PathwayBrowser/#/R-SCE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-1855214 https://reactome.org/PathwayBrowser/#/R-SCE-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Saccharomyces cerevisiae 15377 R-SCE-1855218 https://reactome.org/PathwayBrowser/#/R-SCE-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-1855221 https://reactome.org/PathwayBrowser/#/R-SCE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-189406 https://reactome.org/PathwayBrowser/#/R-SCE-189406 4 PBGs bind to form HMB IEA Saccharomyces cerevisiae 15377 R-SCE-189421 https://reactome.org/PathwayBrowser/#/R-SCE-189421 CPO transforms COPRO3 to PPGEN9 IEA Saccharomyces cerevisiae 15377 R-SCE-189439 https://reactome.org/PathwayBrowser/#/R-SCE-189439 ALAD condenses 2 dALAs to form PBG IEA Saccharomyces cerevisiae 15377 R-SCE-189488 https://reactome.org/PathwayBrowser/#/R-SCE-189488 UROS transforms HMB to URO3 IEA Saccharomyces cerevisiae 15377 R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 15377 R-SCE-191323 https://reactome.org/PathwayBrowser/#/R-SCE-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Saccharomyces cerevisiae 15377 R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 15377 R-SCE-193385 https://reactome.org/PathwayBrowser/#/R-SCE-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Saccharomyces cerevisiae 15377 R-SCE-193711 https://reactome.org/PathwayBrowser/#/R-SCE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 15377 R-SCE-193727 https://reactome.org/PathwayBrowser/#/R-SCE-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 15377 R-SCE-193743 https://reactome.org/PathwayBrowser/#/R-SCE-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 15377 R-SCE-193766 https://reactome.org/PathwayBrowser/#/R-SCE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 15377 R-SCE-194641 https://reactome.org/PathwayBrowser/#/R-SCE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 15377 R-SCE-194669 https://reactome.org/PathwayBrowser/#/R-SCE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 15377 R-SCE-194678 https://reactome.org/PathwayBrowser/#/R-SCE-194678 CYP51A1 demethylates LNSOL IEA Saccharomyces cerevisiae 15377 R-SCE-195664 https://reactome.org/PathwayBrowser/#/R-SCE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Saccharomyces cerevisiae 15377 R-SCE-196955 https://reactome.org/PathwayBrowser/#/R-SCE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Saccharomyces cerevisiae 15377 R-SCE-197271 https://reactome.org/PathwayBrowser/#/R-SCE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Saccharomyces cerevisiae 15377 R-SCE-199456 https://reactome.org/PathwayBrowser/#/R-SCE-199456 PTEN dephosphorylates PIP3 IEA Saccharomyces cerevisiae 15377 R-SCE-199959 https://reactome.org/PathwayBrowser/#/R-SCE-199959 ERKs are inactivated by protein phosphatase 2A IEA Saccharomyces cerevisiae 15377 R-SCE-200661 https://reactome.org/PathwayBrowser/#/R-SCE-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Saccharomyces cerevisiae 15377 R-SCE-200740 https://reactome.org/PathwayBrowser/#/R-SCE-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Saccharomyces cerevisiae 15377 R-SCE-201035 https://reactome.org/PathwayBrowser/#/R-SCE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Saccharomyces cerevisiae 15377 R-SCE-2023971 https://reactome.org/PathwayBrowser/#/R-SCE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-2023973 https://reactome.org/PathwayBrowser/#/R-SCE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-202407 https://reactome.org/PathwayBrowser/#/R-SCE-202407 PLC-gamma1 hydrolyses PIP2 IEA Saccharomyces cerevisiae 15377 R-SCE-2029468 https://reactome.org/PathwayBrowser/#/R-SCE-2029468 Conversion of PA into DAG by PAP-1 IEA Saccharomyces cerevisiae 15377 R-SCE-2029471 https://reactome.org/PathwayBrowser/#/R-SCE-2029471 Hydrolysis of PC to PA by PLD IEA Saccharomyces cerevisiae 15377 R-SCE-2046088 https://reactome.org/PathwayBrowser/#/R-SCE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Saccharomyces cerevisiae 15377 R-SCE-2046094 https://reactome.org/PathwayBrowser/#/R-SCE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Saccharomyces cerevisiae 15377 R-SCE-204662 https://reactome.org/PathwayBrowser/#/R-SCE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Saccharomyces cerevisiae 15377 R-SCE-2066779 https://reactome.org/PathwayBrowser/#/R-SCE-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Saccharomyces cerevisiae 15377 R-SCE-2162194 https://reactome.org/PathwayBrowser/#/R-SCE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Saccharomyces cerevisiae 15377 R-SCE-2162292 https://reactome.org/PathwayBrowser/#/R-SCE-2162292 HHB is hydroxylated to DHHB by Coq6 TAS Saccharomyces cerevisiae 15377 R-SCE-2164813 https://reactome.org/PathwayBrowser/#/R-SCE-2164813 HMPhOH is hydroxylated to MDMQ6H2 by HMPhOH monooxygenase TAS Saccharomyces cerevisiae 15377 R-SCE-2393939 https://reactome.org/PathwayBrowser/#/R-SCE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Saccharomyces cerevisiae 15377 R-SCE-2408518 https://reactome.org/PathwayBrowser/#/R-SCE-2408518 PAPSe is reduced to SeO3(2-) by MET16 TAS Saccharomyces cerevisiae 15377 R-SCE-2408551 https://reactome.org/PathwayBrowser/#/R-SCE-2408551 SeMet is converted to AdoSeMet by MAT IEA Saccharomyces cerevisiae 15377 R-SCE-2509827 https://reactome.org/PathwayBrowser/#/R-SCE-2509827 ITPA hydrolyses ITP to IMP IEA Saccharomyces cerevisiae 15377 R-SCE-2509831 https://reactome.org/PathwayBrowser/#/R-SCE-2509831 ITPA hydrolyses XTP to XMP IEA Saccharomyces cerevisiae 15377 R-SCE-2509838 https://reactome.org/PathwayBrowser/#/R-SCE-2509838 ITPA hydrolyses dITP to dIMP IEA Saccharomyces cerevisiae 15377 R-SCE-2529015 https://reactome.org/PathwayBrowser/#/R-SCE-2529015 Dephosphorylation of CK2-modified condensin I IEA Saccharomyces cerevisiae 15377 R-SCE-265783 https://reactome.org/PathwayBrowser/#/R-SCE-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Saccharomyces cerevisiae 15377 R-SCE-266046 https://reactome.org/PathwayBrowser/#/R-SCE-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Saccharomyces cerevisiae 15377 R-SCE-266072 https://reactome.org/PathwayBrowser/#/R-SCE-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Saccharomyces cerevisiae 15377 R-SCE-266082 https://reactome.org/PathwayBrowser/#/R-SCE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Saccharomyces cerevisiae 15377 R-SCE-2995330 https://reactome.org/PathwayBrowser/#/R-SCE-2995330 COX10 transforms heme to heme O IEA Saccharomyces cerevisiae 15377 R-SCE-2995334 https://reactome.org/PathwayBrowser/#/R-SCE-2995334 COX15 transforms heme O to heme A IEA Saccharomyces cerevisiae 15377 R-SCE-3095901 https://reactome.org/PathwayBrowser/#/R-SCE-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Saccharomyces cerevisiae 15377 R-SCE-3341343 https://reactome.org/PathwayBrowser/#/R-SCE-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Saccharomyces cerevisiae 15377 R-SCE-3697882 https://reactome.org/PathwayBrowser/#/R-SCE-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Saccharomyces cerevisiae 15377 R-SCE-3769447 https://reactome.org/PathwayBrowser/#/R-SCE-3769447 HDAC1:2-containing complex deacetylate histones IEA Saccharomyces cerevisiae 15377 R-SCE-3777129 https://reactome.org/PathwayBrowser/#/R-SCE-3777129 HDAC3 containing complexes deacetylate histone IEA Saccharomyces cerevisiae 15377 R-SCE-3781011 https://reactome.org/PathwayBrowser/#/R-SCE-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Saccharomyces cerevisiae 15377 R-SCE-3781018 https://reactome.org/PathwayBrowser/#/R-SCE-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Saccharomyces cerevisiae 15377 R-SCE-3782637 https://reactome.org/PathwayBrowser/#/R-SCE-3782637 HDAC8 deacetylates histones IEA Saccharomyces cerevisiae 15377 R-SCE-3782655 https://reactome.org/PathwayBrowser/#/R-SCE-3782655 HDAC10 deacetylates histone IEA Saccharomyces cerevisiae 15377 R-SCE-382560 https://reactome.org/PathwayBrowser/#/R-SCE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Saccharomyces cerevisiae 15377 R-SCE-382575 https://reactome.org/PathwayBrowser/#/R-SCE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Saccharomyces cerevisiae 15377 R-SCE-390304 https://reactome.org/PathwayBrowser/#/R-SCE-390304 acetyl-CoA + H2O => acetate + CoASH IEA Saccharomyces cerevisiae 15377 R-SCE-390329 https://reactome.org/PathwayBrowser/#/R-SCE-390329 Dephosphorylation of AKT by PP2A IEA Saccharomyces cerevisiae 15377 R-SCE-399998 https://reactome.org/PathwayBrowser/#/R-SCE-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Saccharomyces cerevisiae 15377 R-SCE-426043 https://reactome.org/PathwayBrowser/#/R-SCE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Saccharomyces cerevisiae 15377 R-SCE-428262 https://reactome.org/PathwayBrowser/#/R-SCE-428262 ACER3 hydrolyzes phytoceramide IEA Saccharomyces cerevisiae 15377 R-SCE-428664 https://reactome.org/PathwayBrowser/#/R-SCE-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Saccharomyces cerevisiae 15377 R-SCE-428690 https://reactome.org/PathwayBrowser/#/R-SCE-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Saccharomyces cerevisiae 15377 R-SCE-428696 https://reactome.org/PathwayBrowser/#/R-SCE-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Saccharomyces cerevisiae 15377 R-SCE-429860 https://reactome.org/PathwayBrowser/#/R-SCE-429860 DCP1-DCP2 complex decaps mRNA IEA Saccharomyces cerevisiae 15377 R-SCE-429913 https://reactome.org/PathwayBrowser/#/R-SCE-429913 5' to 3' Exoribonuclease Digestion of Decapped mRNA (yeast) TAS Saccharomyces cerevisiae 15377 R-SCE-429961 https://reactome.org/PathwayBrowser/#/R-SCE-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Saccharomyces cerevisiae 15377 R-SCE-430021 https://reactome.org/PathwayBrowser/#/R-SCE-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Saccharomyces cerevisiae 15377 R-SCE-430028 https://reactome.org/PathwayBrowser/#/R-SCE-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Saccharomyces cerevisiae 15377 R-SCE-445714 https://reactome.org/PathwayBrowser/#/R-SCE-445714 Aquaporin-3 passively transports water out of cell IEA Saccharomyces cerevisiae 15377 R-SCE-449937 https://reactome.org/PathwayBrowser/#/R-SCE-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Saccharomyces cerevisiae 15377 R-SCE-452036 https://reactome.org/PathwayBrowser/#/R-SCE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Saccharomyces cerevisiae 15377 R-SCE-504054 https://reactome.org/PathwayBrowser/#/R-SCE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Saccharomyces cerevisiae 15377 R-SCE-507868 https://reactome.org/PathwayBrowser/#/R-SCE-507868 Aquaporins passively transport water into cells IEA Saccharomyces cerevisiae 15377 R-SCE-507870 https://reactome.org/PathwayBrowser/#/R-SCE-507870 Aquaporins passively transport water out of cells IEA Saccharomyces cerevisiae 15377 R-SCE-5221130 https://reactome.org/PathwayBrowser/#/R-SCE-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Saccharomyces cerevisiae 15377 R-SCE-5251955 https://reactome.org/PathwayBrowser/#/R-SCE-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Saccharomyces cerevisiae 15377 R-SCE-5251959 https://reactome.org/PathwayBrowser/#/R-SCE-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-5251989 https://reactome.org/PathwayBrowser/#/R-SCE-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Saccharomyces cerevisiae 15377 R-SCE-5362522 https://reactome.org/PathwayBrowser/#/R-SCE-5362522 ALDHs oxidise atRAL to atRA IEA Saccharomyces cerevisiae 15377 R-SCE-5433072 https://reactome.org/PathwayBrowser/#/R-SCE-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Saccharomyces cerevisiae 15377 R-SCE-548843 https://reactome.org/PathwayBrowser/#/R-SCE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Saccharomyces cerevisiae 15377 R-SCE-5607735 https://reactome.org/PathwayBrowser/#/R-SCE-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Saccharomyces cerevisiae 15377 R-SCE-5631885 https://reactome.org/PathwayBrowser/#/R-SCE-5631885 PRDX1 overoxidizes IEA Saccharomyces cerevisiae 15377 R-SCE-5653770 https://reactome.org/PathwayBrowser/#/R-SCE-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Saccharomyces cerevisiae 15377 R-SCE-5676637 https://reactome.org/PathwayBrowser/#/R-SCE-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Saccharomyces cerevisiae 15377 R-SCE-5679041 https://reactome.org/PathwayBrowser/#/R-SCE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 15377 R-SCE-5683405 https://reactome.org/PathwayBrowser/#/R-SCE-5683405 PPP5C dephosphorylates TP53BP1 IEA Saccharomyces cerevisiae 15377 R-SCE-5689950 https://reactome.org/PathwayBrowser/#/R-SCE-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Saccharomyces cerevisiae 15377 R-SCE-5690042 https://reactome.org/PathwayBrowser/#/R-SCE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Saccharomyces cerevisiae 15377 R-SCE-5690080 https://reactome.org/PathwayBrowser/#/R-SCE-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Saccharomyces cerevisiae 15377 R-SCE-5690319 https://reactome.org/PathwayBrowser/#/R-SCE-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Saccharomyces cerevisiae 15377 R-SCE-5690565 https://reactome.org/PathwayBrowser/#/R-SCE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15377 R-SCE-5690808 https://reactome.org/PathwayBrowser/#/R-SCE-5690808 UCHL3, SENP8 cleave NEDD8 IEA Saccharomyces cerevisiae 15377 R-SCE-5692261 https://reactome.org/PathwayBrowser/#/R-SCE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Saccharomyces cerevisiae 15377 R-SCE-5692283 https://reactome.org/PathwayBrowser/#/R-SCE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Saccharomyces cerevisiae 15377 R-SCE-5692462 https://reactome.org/PathwayBrowser/#/R-SCE-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Saccharomyces cerevisiae 15377 R-SCE-5692480 https://reactome.org/PathwayBrowser/#/R-SCE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Saccharomyces cerevisiae 15377 R-SCE-5692754 https://reactome.org/PathwayBrowser/#/R-SCE-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Saccharomyces cerevisiae 15377 R-SCE-5693724 https://reactome.org/PathwayBrowser/#/R-SCE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Saccharomyces cerevisiae 15377 R-SCE-5693761 https://reactome.org/PathwayBrowser/#/R-SCE-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Saccharomyces cerevisiae 15377 R-SCE-5694421 https://reactome.org/PathwayBrowser/#/R-SCE-5694421 PP6 dephosphorylates SEC24 IEA Saccharomyces cerevisiae 15377 R-SCE-5694462 https://reactome.org/PathwayBrowser/#/R-SCE-5694462 ABHD6,12 hydrolyse 3AG IEA Saccharomyces cerevisiae 15377 R-SCE-5694485 https://reactome.org/PathwayBrowser/#/R-SCE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Saccharomyces cerevisiae 15377 R-SCE-5694583 https://reactome.org/PathwayBrowser/#/R-SCE-5694583 ABHD4 hydrolyses NAPE IEA Saccharomyces cerevisiae 15377 R-SCE-5696080 https://reactome.org/PathwayBrowser/#/R-SCE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 15377 R-SCE-5696091 https://reactome.org/PathwayBrowser/#/R-SCE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Saccharomyces cerevisiae 15377 R-SCE-5696564 https://reactome.org/PathwayBrowser/#/R-SCE-5696564 USP25 deubiquitinates DDX58 IEA Saccharomyces cerevisiae 15377 R-SCE-5696600 https://reactome.org/PathwayBrowser/#/R-SCE-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Saccharomyces cerevisiae 15377 R-SCE-5696914 https://reactome.org/PathwayBrowser/#/R-SCE-5696914 USP28 deubiquitinates CLSPN and MYC IEA Saccharomyces cerevisiae 15377 R-SCE-6782069 https://reactome.org/PathwayBrowser/#/R-SCE-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Saccharomyces cerevisiae 15377 R-SCE-6782106 https://reactome.org/PathwayBrowser/#/R-SCE-6782106 USP10 deubiquitinates SNX3, CFTR IEA Saccharomyces cerevisiae 15377 R-SCE-6782820 https://reactome.org/PathwayBrowser/#/R-SCE-6782820 USP17 deubiquitinates SUDS3 IEA Saccharomyces cerevisiae 15377 R-SCE-6783221 https://reactome.org/PathwayBrowser/#/R-SCE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Saccharomyces cerevisiae 15377 R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 15377 R-SCE-6786421 https://reactome.org/PathwayBrowser/#/R-SCE-6786421 CHIA hydrolyses chitin IEA Saccharomyces cerevisiae 15377 R-SCE-6786650 https://reactome.org/PathwayBrowser/#/R-SCE-6786650 DDHD1,2 hydrolyse PA IEA Saccharomyces cerevisiae 15377 R-SCE-6786652 https://reactome.org/PathwayBrowser/#/R-SCE-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Saccharomyces cerevisiae 15377 R-SCE-6788295 https://reactome.org/PathwayBrowser/#/R-SCE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Saccharomyces cerevisiae 15377 R-SCE-6789310 https://reactome.org/PathwayBrowser/#/R-SCE-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Saccharomyces cerevisiae 15377 R-SCE-6790128 https://reactome.org/PathwayBrowser/#/R-SCE-6790128 TAD1 deaminates adenosine-37 in tRNA(Ala) yielding inosine-37 TAS Saccharomyces cerevisiae 15377 R-SCE-6797630 https://reactome.org/PathwayBrowser/#/R-SCE-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Saccharomyces cerevisiae 15377 R-SCE-6799545 https://reactome.org/PathwayBrowser/#/R-SCE-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Saccharomyces cerevisiae 15377 R-SCE-6801462 https://reactome.org/PathwayBrowser/#/R-SCE-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Saccharomyces cerevisiae 15377 R-SCE-6807053 https://reactome.org/PathwayBrowser/#/R-SCE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Saccharomyces cerevisiae 15377 R-SCE-6807118 https://reactome.org/PathwayBrowser/#/R-SCE-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Saccharomyces cerevisiae 15377 R-SCE-6808464 https://reactome.org/PathwayBrowser/#/R-SCE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 15377 R-SCE-6809287 https://reactome.org/PathwayBrowser/#/R-SCE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Saccharomyces cerevisiae 15377 R-SCE-6809320 https://reactome.org/PathwayBrowser/#/R-SCE-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-6809325 https://reactome.org/PathwayBrowser/#/R-SCE-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-6809720 https://reactome.org/PathwayBrowser/#/R-SCE-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Saccharomyces cerevisiae 15377 R-SCE-6809777 https://reactome.org/PathwayBrowser/#/R-SCE-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Saccharomyces cerevisiae 15377 R-SCE-6809778 https://reactome.org/PathwayBrowser/#/R-SCE-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Saccharomyces cerevisiae 15377 R-SCE-6811504 https://reactome.org/PathwayBrowser/#/R-SCE-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Saccharomyces cerevisiae 15377 R-SCE-6813749 https://reactome.org/PathwayBrowser/#/R-SCE-6813749 ALDH1A1 oxidises GA to DGA IEA Saccharomyces cerevisiae 15377 R-SCE-6814254 https://reactome.org/PathwayBrowser/#/R-SCE-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Saccharomyces cerevisiae 15377 R-SCE-6814797 https://reactome.org/PathwayBrowser/#/R-SCE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Saccharomyces cerevisiae 15377 R-SCE-70262 https://reactome.org/PathwayBrowser/#/R-SCE-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Saccharomyces cerevisiae 15377 R-SCE-70479 https://reactome.org/PathwayBrowser/#/R-SCE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Saccharomyces cerevisiae 15377 R-SCE-70494 https://reactome.org/PathwayBrowser/#/R-SCE-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Saccharomyces cerevisiae 15377 R-SCE-70569 https://reactome.org/PathwayBrowser/#/R-SCE-70569 arginine + H2O => ornithine + urea [ARG1] IEA Saccharomyces cerevisiae 15377 R-SCE-70599 https://reactome.org/PathwayBrowser/#/R-SCE-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Saccharomyces cerevisiae 15377 R-SCE-70881 https://reactome.org/PathwayBrowser/#/R-SCE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Saccharomyces cerevisiae 15377 R-SCE-70938 https://reactome.org/PathwayBrowser/#/R-SCE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Saccharomyces cerevisiae 15377 R-SCE-70940 https://reactome.org/PathwayBrowser/#/R-SCE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Saccharomyces cerevisiae 15377 R-SCE-70975 https://reactome.org/PathwayBrowser/#/R-SCE-70975 CS acetylates OA to citrate IEA Saccharomyces cerevisiae 15377 R-SCE-70982 https://reactome.org/PathwayBrowser/#/R-SCE-70982 FH tetramer hydrates fumarate to L-malate IEA Saccharomyces cerevisiae 15377 R-SCE-71146 https://reactome.org/PathwayBrowser/#/R-SCE-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Saccharomyces cerevisiae 15377 R-SCE-71200 https://reactome.org/PathwayBrowser/#/R-SCE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Saccharomyces cerevisiae 15377 R-SCE-71217 https://reactome.org/PathwayBrowser/#/R-SCE-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Saccharomyces cerevisiae 15377 R-SCE-71296 https://reactome.org/PathwayBrowser/#/R-SCE-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Saccharomyces cerevisiae 15377 R-SCE-71660 https://reactome.org/PathwayBrowser/#/R-SCE-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Saccharomyces cerevisiae 15377 R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 15377 R-SCE-71723 https://reactome.org/PathwayBrowser/#/R-SCE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Saccharomyces cerevisiae 15377 R-SCE-71732 https://reactome.org/PathwayBrowser/#/R-SCE-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Saccharomyces cerevisiae 15377 R-SCE-73571 https://reactome.org/PathwayBrowser/#/R-SCE-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Saccharomyces cerevisiae 15377 R-SCE-73577 https://reactome.org/PathwayBrowser/#/R-SCE-73577 CAD hexamer transforms L-Gln to CAP IEA Saccharomyces cerevisiae 15377 R-SCE-73608 https://reactome.org/PathwayBrowser/#/R-SCE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Saccharomyces cerevisiae 15377 R-SCE-73647 https://reactome.org/PathwayBrowser/#/R-SCE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Saccharomyces cerevisiae 15377 R-SCE-73666 https://reactome.org/PathwayBrowser/#/R-SCE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Saccharomyces cerevisiae 15377 R-SCE-73792 https://reactome.org/PathwayBrowser/#/R-SCE-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Saccharomyces cerevisiae 15377 R-SCE-73794 https://reactome.org/PathwayBrowser/#/R-SCE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Saccharomyces cerevisiae 15377 R-SCE-73797 https://reactome.org/PathwayBrowser/#/R-SCE-73797 FAICAR => IMP + H2O IEA Saccharomyces cerevisiae 15377 R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 15377 R-SCE-74255 https://reactome.org/PathwayBrowser/#/R-SCE-74255 Guanine + H2O => Xanthine + NH4+ IEA Saccharomyces cerevisiae 15377 R-SCE-75899 https://reactome.org/PathwayBrowser/#/R-SCE-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Saccharomyces cerevisiae 15377 R-SCE-76031 https://reactome.org/PathwayBrowser/#/R-SCE-76031 2 H2O2 => O2 + 2 H2O IEA Saccharomyces cerevisiae 15377 R-SCE-76590 https://reactome.org/PathwayBrowser/#/R-SCE-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Saccharomyces cerevisiae 15377 R-SCE-8847579 https://reactome.org/PathwayBrowser/#/R-SCE-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15377 R-SCE-8848215 https://reactome.org/PathwayBrowser/#/R-SCE-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Saccharomyces cerevisiae 15377 R-SCE-8848484 https://reactome.org/PathwayBrowser/#/R-SCE-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Saccharomyces cerevisiae 15377 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15377 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 15377 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15377 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15377 R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 15377 R-SCE-8854255 https://reactome.org/PathwayBrowser/#/R-SCE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 15377 R-SCE-8854329 https://reactome.org/PathwayBrowser/#/R-SCE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 15377 R-SCE-8856951 https://reactome.org/PathwayBrowser/#/R-SCE-8856951 PP2A demethylation by PPME1 IEA Saccharomyces cerevisiae 15377 R-SCE-8867344 https://reactome.org/PathwayBrowser/#/R-SCE-8867344 OMA1 hydrolyses OPA1 IEA Saccharomyces cerevisiae 15377 R-SCE-888548 https://reactome.org/PathwayBrowser/#/R-SCE-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Saccharomyces cerevisiae 15377 R-SCE-8940388 https://reactome.org/PathwayBrowser/#/R-SCE-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Saccharomyces cerevisiae 15377 R-SCE-8943279 https://reactome.org/PathwayBrowser/#/R-SCE-8943279 GGT dimers hydrolyse GSH IEA Saccharomyces cerevisiae 15377 R-SCE-8952137 https://reactome.org/PathwayBrowser/#/R-SCE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Saccharomyces cerevisiae 15377 R-SCE-8952251 https://reactome.org/PathwayBrowser/#/R-SCE-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Saccharomyces cerevisiae 15377 R-SCE-8955817 https://reactome.org/PathwayBrowser/#/R-SCE-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Saccharomyces cerevisiae 15377 R-SCE-8979996 https://reactome.org/PathwayBrowser/#/R-SCE-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Saccharomyces cerevisiae 15377 R-SCE-8981637 https://reactome.org/PathwayBrowser/#/R-SCE-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Saccharomyces cerevisiae 15377 R-SCE-9013022 https://reactome.org/PathwayBrowser/#/R-SCE-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Saccharomyces cerevisiae 15377 R-SCE-9013111 https://reactome.org/PathwayBrowser/#/R-SCE-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Saccharomyces cerevisiae 15377 R-SCE-9013161 https://reactome.org/PathwayBrowser/#/R-SCE-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Saccharomyces cerevisiae 15377 R-SCE-9013437 https://reactome.org/PathwayBrowser/#/R-SCE-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Saccharomyces cerevisiae 15377 R-SCE-9014627 https://reactome.org/PathwayBrowser/#/R-SCE-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Saccharomyces cerevisiae 15377 R-SCE-9014741 https://reactome.org/PathwayBrowser/#/R-SCE-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Saccharomyces cerevisiae 15377 R-SCE-9017488 https://reactome.org/PathwayBrowser/#/R-SCE-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Saccharomyces cerevisiae 15377 R-SCE-9018745 https://reactome.org/PathwayBrowser/#/R-SCE-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Saccharomyces cerevisiae 15377 R-SCE-9018814 https://reactome.org/PathwayBrowser/#/R-SCE-9018814 RHOT1 hydrolyzes GTP IEA Saccharomyces cerevisiae 15377 R-SCE-9018826 https://reactome.org/PathwayBrowser/#/R-SCE-9018826 RHOT2 hydrolyzes GTP IEA Saccharomyces cerevisiae 15377 R-SCE-9018862 https://reactome.org/PathwayBrowser/#/R-SCE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Saccharomyces cerevisiae 15377 R-SCE-9018877 https://reactome.org/PathwayBrowser/#/R-SCE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Saccharomyces cerevisiae 15377 R-SCE-9020252 https://reactome.org/PathwayBrowser/#/R-SCE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Saccharomyces cerevisiae 15377 R-SCE-9020253 https://reactome.org/PathwayBrowser/#/R-SCE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Saccharomyces cerevisiae 15377 R-SCE-9020257 https://reactome.org/PathwayBrowser/#/R-SCE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Saccharomyces cerevisiae 15377 R-SCE-9020258 https://reactome.org/PathwayBrowser/#/R-SCE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Saccharomyces cerevisiae 15377 R-SCE-9020270 https://reactome.org/PathwayBrowser/#/R-SCE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Saccharomyces cerevisiae 15377 R-SCE-9024890 https://reactome.org/PathwayBrowser/#/R-SCE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Saccharomyces cerevisiae 15377 R-SCE-9034539 https://reactome.org/PathwayBrowser/#/R-SCE-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Saccharomyces cerevisiae 15377 R-SCE-917841 https://reactome.org/PathwayBrowser/#/R-SCE-917841 Acidification of Tf:TfR1 containing endosome IEA Saccharomyces cerevisiae 15377 R-SCE-917979 https://reactome.org/PathwayBrowser/#/R-SCE-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Saccharomyces cerevisiae 15377 R-SCE-936883 https://reactome.org/PathwayBrowser/#/R-SCE-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Saccharomyces cerevisiae 15377 R-SCE-936895 https://reactome.org/PathwayBrowser/#/R-SCE-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Saccharomyces cerevisiae 15377 R-SCE-939763 https://reactome.org/PathwayBrowser/#/R-SCE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-947591 https://reactome.org/PathwayBrowser/#/R-SCE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Saccharomyces cerevisiae 15377 R-SCE-9620103 https://reactome.org/PathwayBrowser/#/R-SCE-9620103 ALDH2 transforms GTN to NO IEA Saccharomyces cerevisiae 15377 R-SCE-9624893 https://reactome.org/PathwayBrowser/#/R-SCE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Saccharomyces cerevisiae 15377 R-SCE-9635739 https://reactome.org/PathwayBrowser/#/R-SCE-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Saccharomyces cerevisiae 15377 R-SCE-965079 https://reactome.org/PathwayBrowser/#/R-SCE-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Saccharomyces cerevisiae 15377 R-SCE-9653514 https://reactome.org/PathwayBrowser/#/R-SCE-9653514 USP17L2 deubiquitinates RCE1 IEA Saccharomyces cerevisiae 15377 R-SCE-9661417 https://reactome.org/PathwayBrowser/#/R-SCE-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 15377 R-SCE-9673053 https://reactome.org/PathwayBrowser/#/R-SCE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Saccharomyces cerevisiae 15377 R-SCE-9673054 https://reactome.org/PathwayBrowser/#/R-SCE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Saccharomyces cerevisiae 15377 R-SCE-9693282 https://reactome.org/PathwayBrowser/#/R-SCE-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Saccharomyces cerevisiae 15377 R-SCE-9748945 https://reactome.org/PathwayBrowser/#/R-SCE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Saccharomyces cerevisiae 15377 R-SCE-9748957 https://reactome.org/PathwayBrowser/#/R-SCE-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Saccharomyces cerevisiae 15377 R-SCE-9750656 https://reactome.org/PathwayBrowser/#/R-SCE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Saccharomyces cerevisiae 15377 R-SCE-9753278 https://reactome.org/PathwayBrowser/#/R-SCE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 15377 R-SCE-9753283 https://reactome.org/PathwayBrowser/#/R-SCE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 15377 R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 15377 R-SCE-9753632 https://reactome.org/PathwayBrowser/#/R-SCE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Saccharomyces cerevisiae 15377 R-SCE-9753634 https://reactome.org/PathwayBrowser/#/R-SCE-9753634 GGT dimers hydrolyse APAP-SG IEA Saccharomyces cerevisiae 15377 R-SCE-9755030 https://reactome.org/PathwayBrowser/#/R-SCE-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Saccharomyces cerevisiae 15377 R-SCE-977324 https://reactome.org/PathwayBrowser/#/R-SCE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Saccharomyces cerevisiae 15377 R-SCE-9794120 https://reactome.org/PathwayBrowser/#/R-SCE-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Saccharomyces cerevisiae 15377 R-SCE-9794572 https://reactome.org/PathwayBrowser/#/R-SCE-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Saccharomyces cerevisiae 15377 R-SCE-9837419 https://reactome.org/PathwayBrowser/#/R-SCE-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Saccharomyces cerevisiae 15377 R-SCE-9838004 https://reactome.org/PathwayBrowser/#/R-SCE-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 15377 R-SCE-9838081 https://reactome.org/PathwayBrowser/#/R-SCE-9838081 LONP1 degrades mitochondrial matrix proteins IEA Saccharomyces cerevisiae 15377 R-SCE-9839105 https://reactome.org/PathwayBrowser/#/R-SCE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Saccharomyces cerevisiae 15377 R-SCE-9839113 https://reactome.org/PathwayBrowser/#/R-SCE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 15377 R-SCE-9839836 https://reactome.org/PathwayBrowser/#/R-SCE-9839836 YME1 degrades TIM10 TAS Saccharomyces cerevisiae 15377 R-SCE-9843721 https://reactome.org/PathwayBrowser/#/R-SCE-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Saccharomyces cerevisiae 15377 R-SCE-9853385 https://reactome.org/PathwayBrowser/#/R-SCE-9853385 PPP1CC dephosphorylates PLK1 IEA Saccharomyces cerevisiae 15377 R-SPO-111751 https://reactome.org/PathwayBrowser/#/R-SPO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 15377 R-SPO-111804 https://reactome.org/PathwayBrowser/#/R-SPO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 15377 R-SPO-111879 https://reactome.org/PathwayBrowser/#/R-SPO-111879 PIP2 hydrolysis IEA Schizosaccharomyces pombe 15377 R-SPO-111883 https://reactome.org/PathwayBrowser/#/R-SPO-111883 Hydrolysis of phosphatidylcholine IEA Schizosaccharomyces pombe 15377 R-SPO-112037 https://reactome.org/PathwayBrowser/#/R-SPO-112037 Inactivation of PLC beta IEA Schizosaccharomyces pombe 15377 R-SPO-1237129 https://reactome.org/PathwayBrowser/#/R-SPO-1237129 Acireductone is created IEA Schizosaccharomyces pombe 15377 R-SPO-1247910 https://reactome.org/PathwayBrowser/#/R-SPO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Schizosaccharomyces pombe 15377 R-SPO-1247935 https://reactome.org/PathwayBrowser/#/R-SPO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Schizosaccharomyces pombe 15377 R-SPO-1369065 https://reactome.org/PathwayBrowser/#/R-SPO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Schizosaccharomyces pombe 15377 R-SPO-1454916 https://reactome.org/PathwayBrowser/#/R-SPO-1454916 The ABCC family mediates organic anion transport IEA Schizosaccharomyces pombe 15377 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 15377 R-SPO-1474146 https://reactome.org/PathwayBrowser/#/R-SPO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Schizosaccharomyces pombe 15377 R-SPO-1482543 https://reactome.org/PathwayBrowser/#/R-SPO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Schizosaccharomyces pombe 15377 R-SPO-1482545 https://reactome.org/PathwayBrowser/#/R-SPO-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-SPO-1482571 https://reactome.org/PathwayBrowser/#/R-SPO-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-SPO-1482604 https://reactome.org/PathwayBrowser/#/R-SPO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Schizosaccharomyces pombe 15377 R-SPO-1482612 https://reactome.org/PathwayBrowser/#/R-SPO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 15377 R-SPO-1482629 https://reactome.org/PathwayBrowser/#/R-SPO-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-SPO-1482656 https://reactome.org/PathwayBrowser/#/R-SPO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Schizosaccharomyces pombe 15377 R-SPO-1482685 https://reactome.org/PathwayBrowser/#/R-SPO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 15377 R-SPO-1482696 https://reactome.org/PathwayBrowser/#/R-SPO-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-SPO-1482745 https://reactome.org/PathwayBrowser/#/R-SPO-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Schizosaccharomyces pombe 15377 R-SPO-1482759 https://reactome.org/PathwayBrowser/#/R-SPO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Schizosaccharomyces pombe 15377 R-SPO-1482771 https://reactome.org/PathwayBrowser/#/R-SPO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Schizosaccharomyces pombe 15377 R-SPO-1482816 https://reactome.org/PathwayBrowser/#/R-SPO-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Schizosaccharomyces pombe 15377 R-SPO-1482825 https://reactome.org/PathwayBrowser/#/R-SPO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Schizosaccharomyces pombe 15377 R-SPO-1482827 https://reactome.org/PathwayBrowser/#/R-SPO-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-SPO-1482828 https://reactome.org/PathwayBrowser/#/R-SPO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Schizosaccharomyces pombe 15377 R-SPO-1482847 https://reactome.org/PathwayBrowser/#/R-SPO-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Schizosaccharomyces pombe 15377 R-SPO-1482856 https://reactome.org/PathwayBrowser/#/R-SPO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Schizosaccharomyces pombe 15377 R-SPO-1482862 https://reactome.org/PathwayBrowser/#/R-SPO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Schizosaccharomyces pombe 15377 R-SPO-1482868 https://reactome.org/PathwayBrowser/#/R-SPO-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Schizosaccharomyces pombe 15377 R-SPO-1482884 https://reactome.org/PathwayBrowser/#/R-SPO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Schizosaccharomyces pombe 15377 R-SPO-1482892 https://reactome.org/PathwayBrowser/#/R-SPO-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-SPO-1482897 https://reactome.org/PathwayBrowser/#/R-SPO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Schizosaccharomyces pombe 15377 R-SPO-1482900 https://reactome.org/PathwayBrowser/#/R-SPO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Schizosaccharomyces pombe 15377 R-SPO-1482920 https://reactome.org/PathwayBrowser/#/R-SPO-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Schizosaccharomyces pombe 15377 R-SPO-1482932 https://reactome.org/PathwayBrowser/#/R-SPO-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Schizosaccharomyces pombe 15377 R-SPO-1483182 https://reactome.org/PathwayBrowser/#/R-SPO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Schizosaccharomyces pombe 15377 R-SPO-1483203 https://reactome.org/PathwayBrowser/#/R-SPO-1483203 PA is dephosphorylated to DAG by LPIN IEA Schizosaccharomyces pombe 15377 R-SPO-1606273 https://reactome.org/PathwayBrowser/#/R-SPO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Schizosaccharomyces pombe 15377 R-SPO-1606839 https://reactome.org/PathwayBrowser/#/R-SPO-1606839 ARSC hydrolyzes steroid sulfates IEA Schizosaccharomyces pombe 15377 R-SPO-1614583 https://reactome.org/PathwayBrowser/#/R-SPO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Schizosaccharomyces pombe 15377 R-SPO-1614614 https://reactome.org/PathwayBrowser/#/R-SPO-1614614 Cysteine is degraded to serine and H2S IEA Schizosaccharomyces pombe 15377 R-SPO-1614631 https://reactome.org/PathwayBrowser/#/R-SPO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Schizosaccharomyces pombe 15377 R-SPO-162857 https://reactome.org/PathwayBrowser/#/R-SPO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Schizosaccharomyces pombe 15377 R-SPO-1630304 https://reactome.org/PathwayBrowser/#/R-SPO-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Schizosaccharomyces pombe 15377 R-SPO-1640164 https://reactome.org/PathwayBrowser/#/R-SPO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Schizosaccharomyces pombe 15377 R-SPO-1675795 https://reactome.org/PathwayBrowser/#/R-SPO-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1675824 https://reactome.org/PathwayBrowser/#/R-SPO-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1675836 https://reactome.org/PathwayBrowser/#/R-SPO-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1675988 https://reactome.org/PathwayBrowser/#/R-SPO-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1675994 https://reactome.org/PathwayBrowser/#/R-SPO-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1676065 https://reactome.org/PathwayBrowser/#/R-SPO-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1676105 https://reactome.org/PathwayBrowser/#/R-SPO-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1676114 https://reactome.org/PathwayBrowser/#/R-SPO-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1676124 https://reactome.org/PathwayBrowser/#/R-SPO-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1676141 https://reactome.org/PathwayBrowser/#/R-SPO-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1676149 https://reactome.org/PathwayBrowser/#/R-SPO-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1676177 https://reactome.org/PathwayBrowser/#/R-SPO-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1676203 https://reactome.org/PathwayBrowser/#/R-SPO-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1676204 https://reactome.org/PathwayBrowser/#/R-SPO-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Schizosaccharomyces pombe 15377 R-SPO-174110 https://reactome.org/PathwayBrowser/#/R-SPO-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Schizosaccharomyces pombe 15377 R-SPO-174124 https://reactome.org/PathwayBrowser/#/R-SPO-174124 Dephosphorylation of phospho-Cdh1 IEA Schizosaccharomyces pombe 15377 R-SPO-174391 https://reactome.org/PathwayBrowser/#/R-SPO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Schizosaccharomyces pombe 15377 R-SPO-174401 https://reactome.org/PathwayBrowser/#/R-SPO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Schizosaccharomyces pombe 15377 R-SPO-1855165 https://reactome.org/PathwayBrowser/#/R-SPO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 15377 R-SPO-1855166 https://reactome.org/PathwayBrowser/#/R-SPO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Schizosaccharomyces pombe 15377 R-SPO-1855174 https://reactome.org/PathwayBrowser/#/R-SPO-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Schizosaccharomyces pombe 15377 R-SPO-1855177 https://reactome.org/PathwayBrowser/#/R-SPO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1855198 https://reactome.org/PathwayBrowser/#/R-SPO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 15377 R-SPO-1855205 https://reactome.org/PathwayBrowser/#/R-SPO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Schizosaccharomyces pombe 15377 R-SPO-1855213 https://reactome.org/PathwayBrowser/#/R-SPO-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1855214 https://reactome.org/PathwayBrowser/#/R-SPO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1855218 https://reactome.org/PathwayBrowser/#/R-SPO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Schizosaccharomyces pombe 15377 R-SPO-1855221 https://reactome.org/PathwayBrowser/#/R-SPO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-1855222 https://reactome.org/PathwayBrowser/#/R-SPO-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-189053 https://reactome.org/PathwayBrowser/#/R-SPO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Schizosaccharomyces pombe 15377 R-SPO-189069 https://reactome.org/PathwayBrowser/#/R-SPO-189069 sucrose + H2O => glucose + fructose IEA Schizosaccharomyces pombe 15377 R-SPO-189102 https://reactome.org/PathwayBrowser/#/R-SPO-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Schizosaccharomyces pombe 15377 R-SPO-189406 https://reactome.org/PathwayBrowser/#/R-SPO-189406 4 PBGs bind to form HMB IEA Schizosaccharomyces pombe 15377 R-SPO-189421 https://reactome.org/PathwayBrowser/#/R-SPO-189421 CPO transforms COPRO3 to PPGEN9 IEA Schizosaccharomyces pombe 15377 R-SPO-189439 https://reactome.org/PathwayBrowser/#/R-SPO-189439 ALAD condenses 2 dALAs to form PBG IEA Schizosaccharomyces pombe 15377 R-SPO-189488 https://reactome.org/PathwayBrowser/#/R-SPO-189488 UROS transforms HMB to URO3 IEA Schizosaccharomyces pombe 15377 R-SPO-191101 https://reactome.org/PathwayBrowser/#/R-SPO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 15377 R-SPO-191108 https://reactome.org/PathwayBrowser/#/R-SPO-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 15377 R-SPO-191116 https://reactome.org/PathwayBrowser/#/R-SPO-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Schizosaccharomyces pombe 15377 R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 15377 R-SPO-191323 https://reactome.org/PathwayBrowser/#/R-SPO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Schizosaccharomyces pombe 15377 R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 15377 R-SPO-193362 https://reactome.org/PathwayBrowser/#/R-SPO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 15377 R-SPO-194641 https://reactome.org/PathwayBrowser/#/R-SPO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 15377 R-SPO-194669 https://reactome.org/PathwayBrowser/#/R-SPO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 15377 R-SPO-194678 https://reactome.org/PathwayBrowser/#/R-SPO-194678 CYP51A1 demethylates LNSOL IEA Schizosaccharomyces pombe 15377 R-SPO-195664 https://reactome.org/PathwayBrowser/#/R-SPO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Schizosaccharomyces pombe 15377 R-SPO-196955 https://reactome.org/PathwayBrowser/#/R-SPO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Schizosaccharomyces pombe 15377 R-SPO-197271 https://reactome.org/PathwayBrowser/#/R-SPO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Schizosaccharomyces pombe 15377 R-SPO-199456 https://reactome.org/PathwayBrowser/#/R-SPO-199456 PTEN dephosphorylates PIP3 IEA Schizosaccharomyces pombe 15377 R-SPO-199959 https://reactome.org/PathwayBrowser/#/R-SPO-199959 ERKs are inactivated by protein phosphatase 2A IEA Schizosaccharomyces pombe 15377 R-SPO-200661 https://reactome.org/PathwayBrowser/#/R-SPO-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Schizosaccharomyces pombe 15377 R-SPO-200740 https://reactome.org/PathwayBrowser/#/R-SPO-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Schizosaccharomyces pombe 15377 R-SPO-201035 https://reactome.org/PathwayBrowser/#/R-SPO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Schizosaccharomyces pombe 15377 R-SPO-2023971 https://reactome.org/PathwayBrowser/#/R-SPO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 15377 R-SPO-2023973 https://reactome.org/PathwayBrowser/#/R-SPO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 15377 R-SPO-202407 https://reactome.org/PathwayBrowser/#/R-SPO-202407 PLC-gamma1 hydrolyses PIP2 IEA Schizosaccharomyces pombe 15377 R-SPO-2029468 https://reactome.org/PathwayBrowser/#/R-SPO-2029468 Conversion of PA into DAG by PAP-1 IEA Schizosaccharomyces pombe 15377 R-SPO-2029471 https://reactome.org/PathwayBrowser/#/R-SPO-2029471 Hydrolysis of PC to PA by PLD IEA Schizosaccharomyces pombe 15377 R-SPO-2046088 https://reactome.org/PathwayBrowser/#/R-SPO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Schizosaccharomyces pombe 15377 R-SPO-2046094 https://reactome.org/PathwayBrowser/#/R-SPO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Schizosaccharomyces pombe 15377 R-SPO-204662 https://reactome.org/PathwayBrowser/#/R-SPO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Schizosaccharomyces pombe 15377 R-SPO-2162194 https://reactome.org/PathwayBrowser/#/R-SPO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Schizosaccharomyces pombe 15377 R-SPO-2393939 https://reactome.org/PathwayBrowser/#/R-SPO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Schizosaccharomyces pombe 15377 R-SPO-2408551 https://reactome.org/PathwayBrowser/#/R-SPO-2408551 SeMet is converted to AdoSeMet by MAT IEA Schizosaccharomyces pombe 15377 R-SPO-2509827 https://reactome.org/PathwayBrowser/#/R-SPO-2509827 ITPA hydrolyses ITP to IMP IEA Schizosaccharomyces pombe 15377 R-SPO-2509831 https://reactome.org/PathwayBrowser/#/R-SPO-2509831 ITPA hydrolyses XTP to XMP IEA Schizosaccharomyces pombe 15377 R-SPO-2509838 https://reactome.org/PathwayBrowser/#/R-SPO-2509838 ITPA hydrolyses dITP to dIMP IEA Schizosaccharomyces pombe 15377 R-SPO-2529015 https://reactome.org/PathwayBrowser/#/R-SPO-2529015 Dephosphorylation of CK2-modified condensin I IEA Schizosaccharomyces pombe 15377 R-SPO-266012 https://reactome.org/PathwayBrowser/#/R-SPO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Schizosaccharomyces pombe 15377 R-SPO-266046 https://reactome.org/PathwayBrowser/#/R-SPO-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Schizosaccharomyces pombe 15377 R-SPO-266072 https://reactome.org/PathwayBrowser/#/R-SPO-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Schizosaccharomyces pombe 15377 R-SPO-2995330 https://reactome.org/PathwayBrowser/#/R-SPO-2995330 COX10 transforms heme to heme O IEA Schizosaccharomyces pombe 15377 R-SPO-2995334 https://reactome.org/PathwayBrowser/#/R-SPO-2995334 COX15 transforms heme O to heme A IEA Schizosaccharomyces pombe 15377 R-SPO-3095901 https://reactome.org/PathwayBrowser/#/R-SPO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Schizosaccharomyces pombe 15377 R-SPO-3341343 https://reactome.org/PathwayBrowser/#/R-SPO-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Schizosaccharomyces pombe 15377 R-SPO-3697882 https://reactome.org/PathwayBrowser/#/R-SPO-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Schizosaccharomyces pombe 15377 R-SPO-3769447 https://reactome.org/PathwayBrowser/#/R-SPO-3769447 HDAC1:2-containing complex deacetylate histones IEA Schizosaccharomyces pombe 15377 R-SPO-3782655 https://reactome.org/PathwayBrowser/#/R-SPO-3782655 HDAC10 deacetylates histone IEA Schizosaccharomyces pombe 15377 R-SPO-382560 https://reactome.org/PathwayBrowser/#/R-SPO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Schizosaccharomyces pombe 15377 R-SPO-389821 https://reactome.org/PathwayBrowser/#/R-SPO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Schizosaccharomyces pombe 15377 R-SPO-390329 https://reactome.org/PathwayBrowser/#/R-SPO-390329 Dephosphorylation of AKT by PP2A IEA Schizosaccharomyces pombe 15377 R-SPO-399998 https://reactome.org/PathwayBrowser/#/R-SPO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Schizosaccharomyces pombe 15377 R-SPO-426043 https://reactome.org/PathwayBrowser/#/R-SPO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Schizosaccharomyces pombe 15377 R-SPO-428259 https://reactome.org/PathwayBrowser/#/R-SPO-428259 DEGS1 dehydrogenates dihydroceramide IEA Schizosaccharomyces pombe 15377 R-SPO-428260 https://reactome.org/PathwayBrowser/#/R-SPO-428260 DEGS2 oxygenates dihydroceramide IEA Schizosaccharomyces pombe 15377 R-SPO-428664 https://reactome.org/PathwayBrowser/#/R-SPO-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Schizosaccharomyces pombe 15377 R-SPO-428690 https://reactome.org/PathwayBrowser/#/R-SPO-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Schizosaccharomyces pombe 15377 R-SPO-428696 https://reactome.org/PathwayBrowser/#/R-SPO-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Schizosaccharomyces pombe 15377 R-SPO-429961 https://reactome.org/PathwayBrowser/#/R-SPO-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Schizosaccharomyces pombe 15377 R-SPO-430028 https://reactome.org/PathwayBrowser/#/R-SPO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Schizosaccharomyces pombe 15377 R-SPO-4419948 https://reactome.org/PathwayBrowser/#/R-SPO-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Schizosaccharomyces pombe 15377 R-SPO-445714 https://reactome.org/PathwayBrowser/#/R-SPO-445714 Aquaporin-3 passively transports water out of cell IEA Schizosaccharomyces pombe 15377 R-SPO-446200 https://reactome.org/PathwayBrowser/#/R-SPO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Schizosaccharomyces pombe 15377 R-SPO-449937 https://reactome.org/PathwayBrowser/#/R-SPO-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Schizosaccharomyces pombe 15377 R-SPO-452036 https://reactome.org/PathwayBrowser/#/R-SPO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Schizosaccharomyces pombe 15377 R-SPO-504054 https://reactome.org/PathwayBrowser/#/R-SPO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Schizosaccharomyces pombe 15377 R-SPO-507868 https://reactome.org/PathwayBrowser/#/R-SPO-507868 Aquaporins passively transport water into cells IEA Schizosaccharomyces pombe 15377 R-SPO-507870 https://reactome.org/PathwayBrowser/#/R-SPO-507870 Aquaporins passively transport water out of cells IEA Schizosaccharomyces pombe 15377 R-SPO-5221130 https://reactome.org/PathwayBrowser/#/R-SPO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Schizosaccharomyces pombe 15377 R-SPO-5223317 https://reactome.org/PathwayBrowser/#/R-SPO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 15377 R-SPO-5251955 https://reactome.org/PathwayBrowser/#/R-SPO-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Schizosaccharomyces pombe 15377 R-SPO-5251959 https://reactome.org/PathwayBrowser/#/R-SPO-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Schizosaccharomyces pombe 15377 R-SPO-5251989 https://reactome.org/PathwayBrowser/#/R-SPO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Schizosaccharomyces pombe 15377 R-SPO-5362522 https://reactome.org/PathwayBrowser/#/R-SPO-5362522 ALDHs oxidise atRAL to atRA IEA Schizosaccharomyces pombe 15377 R-SPO-5433072 https://reactome.org/PathwayBrowser/#/R-SPO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Schizosaccharomyces pombe 15377 R-SPO-548843 https://reactome.org/PathwayBrowser/#/R-SPO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Schizosaccharomyces pombe 15377 R-SPO-5607735 https://reactome.org/PathwayBrowser/#/R-SPO-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Schizosaccharomyces pombe 15377 R-SPO-5631885 https://reactome.org/PathwayBrowser/#/R-SPO-5631885 PRDX1 overoxidizes IEA Schizosaccharomyces pombe 15377 R-SPO-5653770 https://reactome.org/PathwayBrowser/#/R-SPO-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Schizosaccharomyces pombe 15377 R-SPO-5659861 https://reactome.org/PathwayBrowser/#/R-SPO-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 15377 R-SPO-5676637 https://reactome.org/PathwayBrowser/#/R-SPO-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Schizosaccharomyces pombe 15377 R-SPO-5678706 https://reactome.org/PathwayBrowser/#/R-SPO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Schizosaccharomyces pombe 15377 R-SPO-5679041 https://reactome.org/PathwayBrowser/#/R-SPO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Schizosaccharomyces pombe 15377 R-SPO-5683405 https://reactome.org/PathwayBrowser/#/R-SPO-5683405 PPP5C dephosphorylates TP53BP1 IEA Schizosaccharomyces pombe 15377 R-SPO-5687464 https://reactome.org/PathwayBrowser/#/R-SPO-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Schizosaccharomyces pombe 15377 R-SPO-5687664 https://reactome.org/PathwayBrowser/#/R-SPO-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Schizosaccharomyces pombe 15377 R-SPO-5689000 https://reactome.org/PathwayBrowser/#/R-SPO-5689000 AADAC deacetylates PHEN IEA Schizosaccharomyces pombe 15377 R-SPO-5689950 https://reactome.org/PathwayBrowser/#/R-SPO-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Schizosaccharomyces pombe 15377 R-SPO-5690043 https://reactome.org/PathwayBrowser/#/R-SPO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Schizosaccharomyces pombe 15377 R-SPO-5690080 https://reactome.org/PathwayBrowser/#/R-SPO-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Schizosaccharomyces pombe 15377 R-SPO-5690152 https://reactome.org/PathwayBrowser/#/R-SPO-5690152 USP5 cleaves polyubiquitin IEA Schizosaccharomyces pombe 15377 R-SPO-5690319 https://reactome.org/PathwayBrowser/#/R-SPO-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Schizosaccharomyces pombe 15377 R-SPO-5690565 https://reactome.org/PathwayBrowser/#/R-SPO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15377 R-SPO-5690808 https://reactome.org/PathwayBrowser/#/R-SPO-5690808 UCHL3, SENP8 cleave NEDD8 IEA Schizosaccharomyces pombe 15377 R-SPO-5692462 https://reactome.org/PathwayBrowser/#/R-SPO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Schizosaccharomyces pombe 15377 R-SPO-5692480 https://reactome.org/PathwayBrowser/#/R-SPO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 15377 R-SPO-5692754 https://reactome.org/PathwayBrowser/#/R-SPO-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Schizosaccharomyces pombe 15377 R-SPO-5693761 https://reactome.org/PathwayBrowser/#/R-SPO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Schizosaccharomyces pombe 15377 R-SPO-5694583 https://reactome.org/PathwayBrowser/#/R-SPO-5694583 ABHD4 hydrolyses NAPE IEA Schizosaccharomyces pombe 15377 R-SPO-5696091 https://reactome.org/PathwayBrowser/#/R-SPO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Schizosaccharomyces pombe 15377 R-SPO-5696600 https://reactome.org/PathwayBrowser/#/R-SPO-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Schizosaccharomyces pombe 15377 R-SPO-5696605 https://reactome.org/PathwayBrowser/#/R-SPO-5696605 USP12, USP26 deubiquitinate AR IEA Schizosaccharomyces pombe 15377 R-SPO-5696872 https://reactome.org/PathwayBrowser/#/R-SPO-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Schizosaccharomyces pombe 15377 R-SPO-5696914 https://reactome.org/PathwayBrowser/#/R-SPO-5696914 USP28 deubiquitinates CLSPN and MYC IEA Schizosaccharomyces pombe 15377 R-SPO-5697009 https://reactome.org/PathwayBrowser/#/R-SPO-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Schizosaccharomyces pombe 15377 R-SPO-6781779 https://reactome.org/PathwayBrowser/#/R-SPO-6781779 USP13 deubiquitinates BECN1,USP10 IEA Schizosaccharomyces pombe 15377 R-SPO-6782069 https://reactome.org/PathwayBrowser/#/R-SPO-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Schizosaccharomyces pombe 15377 R-SPO-6782106 https://reactome.org/PathwayBrowser/#/R-SPO-6782106 USP10 deubiquitinates SNX3, CFTR IEA Schizosaccharomyces pombe 15377 R-SPO-6782820 https://reactome.org/PathwayBrowser/#/R-SPO-6782820 USP17 deubiquitinates SUDS3 IEA Schizosaccharomyces pombe 15377 R-SPO-6783221 https://reactome.org/PathwayBrowser/#/R-SPO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Schizosaccharomyces pombe 15377 R-SPO-6786650 https://reactome.org/PathwayBrowser/#/R-SPO-6786650 DDHD1,2 hydrolyse PA IEA Schizosaccharomyces pombe 15377 R-SPO-6788295 https://reactome.org/PathwayBrowser/#/R-SPO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Schizosaccharomyces pombe 15377 R-SPO-6789310 https://reactome.org/PathwayBrowser/#/R-SPO-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Schizosaccharomyces pombe 15377 R-SPO-6797630 https://reactome.org/PathwayBrowser/#/R-SPO-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Schizosaccharomyces pombe 15377 R-SPO-6799545 https://reactome.org/PathwayBrowser/#/R-SPO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Schizosaccharomyces pombe 15377 R-SPO-6801462 https://reactome.org/PathwayBrowser/#/R-SPO-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Schizosaccharomyces pombe 15377 R-SPO-6807053 https://reactome.org/PathwayBrowser/#/R-SPO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Schizosaccharomyces pombe 15377 R-SPO-6807118 https://reactome.org/PathwayBrowser/#/R-SPO-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Schizosaccharomyces pombe 15377 R-SPO-6807206 https://reactome.org/PathwayBrowser/#/R-SPO-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Schizosaccharomyces pombe 15377 R-SPO-6809287 https://reactome.org/PathwayBrowser/#/R-SPO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Schizosaccharomyces pombe 15377 R-SPO-6809320 https://reactome.org/PathwayBrowser/#/R-SPO-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-6809325 https://reactome.org/PathwayBrowser/#/R-SPO-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-6809720 https://reactome.org/PathwayBrowser/#/R-SPO-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Schizosaccharomyces pombe 15377 R-SPO-6809777 https://reactome.org/PathwayBrowser/#/R-SPO-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Schizosaccharomyces pombe 15377 R-SPO-6809778 https://reactome.org/PathwayBrowser/#/R-SPO-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Schizosaccharomyces pombe 15377 R-SPO-6810076 https://reactome.org/PathwayBrowser/#/R-SPO-6810076 DDO oxidizes D-Asp to OA IEA Schizosaccharomyces pombe 15377 R-SPO-6811504 https://reactome.org/PathwayBrowser/#/R-SPO-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Schizosaccharomyces pombe 15377 R-SPO-6813720 https://reactome.org/PathwayBrowser/#/R-SPO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Schizosaccharomyces pombe 15377 R-SPO-6813749 https://reactome.org/PathwayBrowser/#/R-SPO-6813749 ALDH1A1 oxidises GA to DGA IEA Schizosaccharomyces pombe 15377 R-SPO-6814254 https://reactome.org/PathwayBrowser/#/R-SPO-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Schizosaccharomyces pombe 15377 R-SPO-6814797 https://reactome.org/PathwayBrowser/#/R-SPO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Schizosaccharomyces pombe 15377 R-SPO-70262 https://reactome.org/PathwayBrowser/#/R-SPO-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Schizosaccharomyces pombe 15377 R-SPO-70479 https://reactome.org/PathwayBrowser/#/R-SPO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Schizosaccharomyces pombe 15377 R-SPO-70494 https://reactome.org/PathwayBrowser/#/R-SPO-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Schizosaccharomyces pombe 15377 R-SPO-70569 https://reactome.org/PathwayBrowser/#/R-SPO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Schizosaccharomyces pombe 15377 R-SPO-70599 https://reactome.org/PathwayBrowser/#/R-SPO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Schizosaccharomyces pombe 15377 R-SPO-70881 https://reactome.org/PathwayBrowser/#/R-SPO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Schizosaccharomyces pombe 15377 R-SPO-70938 https://reactome.org/PathwayBrowser/#/R-SPO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Schizosaccharomyces pombe 15377 R-SPO-70940 https://reactome.org/PathwayBrowser/#/R-SPO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Schizosaccharomyces pombe 15377 R-SPO-70975 https://reactome.org/PathwayBrowser/#/R-SPO-70975 CS acetylates OA to citrate IEA Schizosaccharomyces pombe 15377 R-SPO-70982 https://reactome.org/PathwayBrowser/#/R-SPO-70982 FH tetramer hydrates fumarate to L-malate IEA Schizosaccharomyces pombe 15377 R-SPO-71146 https://reactome.org/PathwayBrowser/#/R-SPO-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Schizosaccharomyces pombe 15377 R-SPO-71296 https://reactome.org/PathwayBrowser/#/R-SPO-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Schizosaccharomyces pombe 15377 R-SPO-71660 https://reactome.org/PathwayBrowser/#/R-SPO-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Schizosaccharomyces pombe 15377 R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 15377 R-SPO-71723 https://reactome.org/PathwayBrowser/#/R-SPO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Schizosaccharomyces pombe 15377 R-SPO-71732 https://reactome.org/PathwayBrowser/#/R-SPO-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Schizosaccharomyces pombe 15377 R-SPO-73571 https://reactome.org/PathwayBrowser/#/R-SPO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Schizosaccharomyces pombe 15377 R-SPO-73577 https://reactome.org/PathwayBrowser/#/R-SPO-73577 CAD hexamer transforms L-Gln to CAP IEA Schizosaccharomyces pombe 15377 R-SPO-73591 https://reactome.org/PathwayBrowser/#/R-SPO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Schizosaccharomyces pombe 15377 R-SPO-73608 https://reactome.org/PathwayBrowser/#/R-SPO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Schizosaccharomyces pombe 15377 R-SPO-73620 https://reactome.org/PathwayBrowser/#/R-SPO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Schizosaccharomyces pombe 15377 R-SPO-73647 https://reactome.org/PathwayBrowser/#/R-SPO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Schizosaccharomyces pombe 15377 R-SPO-73666 https://reactome.org/PathwayBrowser/#/R-SPO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Schizosaccharomyces pombe 15377 R-SPO-73792 https://reactome.org/PathwayBrowser/#/R-SPO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Schizosaccharomyces pombe 15377 R-SPO-73794 https://reactome.org/PathwayBrowser/#/R-SPO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Schizosaccharomyces pombe 15377 R-SPO-73797 https://reactome.org/PathwayBrowser/#/R-SPO-73797 FAICAR => IMP + H2O IEA Schizosaccharomyces pombe 15377 R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 15377 R-SPO-74255 https://reactome.org/PathwayBrowser/#/R-SPO-74255 Guanine + H2O => Xanthine + NH4+ IEA Schizosaccharomyces pombe 15377 R-SPO-75899 https://reactome.org/PathwayBrowser/#/R-SPO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Schizosaccharomyces pombe 15377 R-SPO-76031 https://reactome.org/PathwayBrowser/#/R-SPO-76031 2 H2O2 => O2 + 2 H2O IEA Schizosaccharomyces pombe 15377 R-SPO-76590 https://reactome.org/PathwayBrowser/#/R-SPO-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Schizosaccharomyces pombe 15377 R-SPO-8847579 https://reactome.org/PathwayBrowser/#/R-SPO-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15377 R-SPO-8848215 https://reactome.org/PathwayBrowser/#/R-SPO-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Schizosaccharomyces pombe 15377 R-SPO-8848484 https://reactome.org/PathwayBrowser/#/R-SPO-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Schizosaccharomyces pombe 15377 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15377 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 15377 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15377 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15377 R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 15377 R-SPO-8854255 https://reactome.org/PathwayBrowser/#/R-SPO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 15377 R-SPO-8854329 https://reactome.org/PathwayBrowser/#/R-SPO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 15377 R-SPO-8856951 https://reactome.org/PathwayBrowser/#/R-SPO-8856951 PP2A demethylation by PPME1 IEA Schizosaccharomyces pombe 15377 R-SPO-8867344 https://reactome.org/PathwayBrowser/#/R-SPO-8867344 OMA1 hydrolyses OPA1 IEA Schizosaccharomyces pombe 15377 R-SPO-8869206 https://reactome.org/PathwayBrowser/#/R-SPO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Schizosaccharomyces pombe 15377 R-SPO-8878654 https://reactome.org/PathwayBrowser/#/R-SPO-8878654 ACP6 hydrolyses MYS-LPA IEA Schizosaccharomyces pombe 15377 R-SPO-888548 https://reactome.org/PathwayBrowser/#/R-SPO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Schizosaccharomyces pombe 15377 R-SPO-8943279 https://reactome.org/PathwayBrowser/#/R-SPO-8943279 GGT dimers hydrolyse GSH IEA Schizosaccharomyces pombe 15377 R-SPO-8955817 https://reactome.org/PathwayBrowser/#/R-SPO-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Schizosaccharomyces pombe 15377 R-SPO-8979996 https://reactome.org/PathwayBrowser/#/R-SPO-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Schizosaccharomyces pombe 15377 R-SPO-8981637 https://reactome.org/PathwayBrowser/#/R-SPO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Schizosaccharomyces pombe 15377 R-SPO-9013022 https://reactome.org/PathwayBrowser/#/R-SPO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Schizosaccharomyces pombe 15377 R-SPO-9013111 https://reactome.org/PathwayBrowser/#/R-SPO-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Schizosaccharomyces pombe 15377 R-SPO-9013161 https://reactome.org/PathwayBrowser/#/R-SPO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Schizosaccharomyces pombe 15377 R-SPO-9013437 https://reactome.org/PathwayBrowser/#/R-SPO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Schizosaccharomyces pombe 15377 R-SPO-9014741 https://reactome.org/PathwayBrowser/#/R-SPO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Schizosaccharomyces pombe 15377 R-SPO-9017488 https://reactome.org/PathwayBrowser/#/R-SPO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Schizosaccharomyces pombe 15377 R-SPO-9018745 https://reactome.org/PathwayBrowser/#/R-SPO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Schizosaccharomyces pombe 15377 R-SPO-9018814 https://reactome.org/PathwayBrowser/#/R-SPO-9018814 RHOT1 hydrolyzes GTP IEA Schizosaccharomyces pombe 15377 R-SPO-9018826 https://reactome.org/PathwayBrowser/#/R-SPO-9018826 RHOT2 hydrolyzes GTP IEA Schizosaccharomyces pombe 15377 R-SPO-9018862 https://reactome.org/PathwayBrowser/#/R-SPO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Schizosaccharomyces pombe 15377 R-SPO-9018877 https://reactome.org/PathwayBrowser/#/R-SPO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Schizosaccharomyces pombe 15377 R-SPO-9020252 https://reactome.org/PathwayBrowser/#/R-SPO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Schizosaccharomyces pombe 15377 R-SPO-9020253 https://reactome.org/PathwayBrowser/#/R-SPO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Schizosaccharomyces pombe 15377 R-SPO-9020257 https://reactome.org/PathwayBrowser/#/R-SPO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Schizosaccharomyces pombe 15377 R-SPO-9020258 https://reactome.org/PathwayBrowser/#/R-SPO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Schizosaccharomyces pombe 15377 R-SPO-9020270 https://reactome.org/PathwayBrowser/#/R-SPO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Schizosaccharomyces pombe 15377 R-SPO-9024890 https://reactome.org/PathwayBrowser/#/R-SPO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Schizosaccharomyces pombe 15377 R-SPO-9034539 https://reactome.org/PathwayBrowser/#/R-SPO-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Schizosaccharomyces pombe 15377 R-SPO-9036727 https://reactome.org/PathwayBrowser/#/R-SPO-9036727 GAA hydrolyzes lysosomal glycogen IEA Schizosaccharomyces pombe 15377 R-SPO-917841 https://reactome.org/PathwayBrowser/#/R-SPO-917841 Acidification of Tf:TfR1 containing endosome IEA Schizosaccharomyces pombe 15377 R-SPO-936883 https://reactome.org/PathwayBrowser/#/R-SPO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Schizosaccharomyces pombe 15377 R-SPO-936895 https://reactome.org/PathwayBrowser/#/R-SPO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Schizosaccharomyces pombe 15377 R-SPO-939763 https://reactome.org/PathwayBrowser/#/R-SPO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-947591 https://reactome.org/PathwayBrowser/#/R-SPO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Schizosaccharomyces pombe 15377 R-SPO-9620103 https://reactome.org/PathwayBrowser/#/R-SPO-9620103 ALDH2 transforms GTN to NO IEA Schizosaccharomyces pombe 15377 R-SPO-9624893 https://reactome.org/PathwayBrowser/#/R-SPO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Schizosaccharomyces pombe 15377 R-SPO-9635739 https://reactome.org/PathwayBrowser/#/R-SPO-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Schizosaccharomyces pombe 15377 R-SPO-965079 https://reactome.org/PathwayBrowser/#/R-SPO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Schizosaccharomyces pombe 15377 R-SPO-9653514 https://reactome.org/PathwayBrowser/#/R-SPO-9653514 USP17L2 deubiquitinates RCE1 IEA Schizosaccharomyces pombe 15377 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 15377 R-SPO-9673053 https://reactome.org/PathwayBrowser/#/R-SPO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Schizosaccharomyces pombe 15377 R-SPO-9673054 https://reactome.org/PathwayBrowser/#/R-SPO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Schizosaccharomyces pombe 15377 R-SPO-9674127 https://reactome.org/PathwayBrowser/#/R-SPO-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Schizosaccharomyces pombe 15377 R-SPO-9693282 https://reactome.org/PathwayBrowser/#/R-SPO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Schizosaccharomyces pombe 15377 R-SPO-9748945 https://reactome.org/PathwayBrowser/#/R-SPO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Schizosaccharomyces pombe 15377 R-SPO-9748957 https://reactome.org/PathwayBrowser/#/R-SPO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Schizosaccharomyces pombe 15377 R-SPO-9750656 https://reactome.org/PathwayBrowser/#/R-SPO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Schizosaccharomyces pombe 15377 R-SPO-9753278 https://reactome.org/PathwayBrowser/#/R-SPO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 15377 R-SPO-9753283 https://reactome.org/PathwayBrowser/#/R-SPO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 15377 R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 15377 R-SPO-9753632 https://reactome.org/PathwayBrowser/#/R-SPO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Schizosaccharomyces pombe 15377 R-SPO-9753634 https://reactome.org/PathwayBrowser/#/R-SPO-9753634 GGT dimers hydrolyse APAP-SG IEA Schizosaccharomyces pombe 15377 R-SPO-9755030 https://reactome.org/PathwayBrowser/#/R-SPO-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Schizosaccharomyces pombe 15377 R-SPO-9759454 https://reactome.org/PathwayBrowser/#/R-SPO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Schizosaccharomyces pombe 15377 R-SPO-9759461 https://reactome.org/PathwayBrowser/#/R-SPO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Schizosaccharomyces pombe 15377 R-SPO-977324 https://reactome.org/PathwayBrowser/#/R-SPO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Schizosaccharomyces pombe 15377 R-SPO-983144 https://reactome.org/PathwayBrowser/#/R-SPO-983144 Transport of Antigen peptide in to ER IEA Schizosaccharomyces pombe 15377 R-SPO-9837419 https://reactome.org/PathwayBrowser/#/R-SPO-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Schizosaccharomyces pombe 15377 R-SPO-9838004 https://reactome.org/PathwayBrowser/#/R-SPO-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 15377 R-SPO-9838081 https://reactome.org/PathwayBrowser/#/R-SPO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Schizosaccharomyces pombe 15377 R-SPO-9839105 https://reactome.org/PathwayBrowser/#/R-SPO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Schizosaccharomyces pombe 15377 R-SPO-9839113 https://reactome.org/PathwayBrowser/#/R-SPO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 15377 R-SPO-9840949 https://reactome.org/PathwayBrowser/#/R-SPO-9840949 ARSA removes sulfate from SM3 IEA Schizosaccharomyces pombe 15377 R-SPO-9843721 https://reactome.org/PathwayBrowser/#/R-SPO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Schizosaccharomyces pombe 15377 R-SPO-9853385 https://reactome.org/PathwayBrowser/#/R-SPO-9853385 PPP1CC dephosphorylates PLK1 IEA Schizosaccharomyces pombe 15377 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 15377 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 15377 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 15377 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 15377 R-SSC-109415 https://reactome.org/PathwayBrowser/#/R-SSC-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Sus scrofa 15377 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 15377 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 15377 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 15377 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 15377 R-SSC-111742 https://reactome.org/PathwayBrowser/#/R-SSC-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 15377 R-SSC-111751 https://reactome.org/PathwayBrowser/#/R-SSC-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 15377 R-SSC-111804 https://reactome.org/PathwayBrowser/#/R-SSC-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 15377 R-SSC-111879 https://reactome.org/PathwayBrowser/#/R-SSC-111879 PIP2 hydrolysis IEA Sus scrofa 15377 R-SSC-111883 https://reactome.org/PathwayBrowser/#/R-SSC-111883 Hydrolysis of phosphatidylcholine IEA Sus scrofa 15377 R-SSC-111955 https://reactome.org/PathwayBrowser/#/R-SSC-111955 cAMP hydrolysis by Cam-PDE 1 IEA Sus scrofa 15377 R-SSC-111962 https://reactome.org/PathwayBrowser/#/R-SSC-111962 PDE4A,C,D hydrolyse cAMP IEA Sus scrofa 15377 R-SSC-112037 https://reactome.org/PathwayBrowser/#/R-SSC-112037 Inactivation of PLC beta IEA Sus scrofa 15377 R-SSC-113503 https://reactome.org/PathwayBrowser/#/R-SSC-113503 PP2A mediated localization of RB1 protein in chromatin IEA Sus scrofa 15377 R-SSC-1169192 https://reactome.org/PathwayBrowser/#/R-SSC-1169192 PTP1B dephosphorylates GHR IEA Sus scrofa 15377 R-SSC-1183128 https://reactome.org/PathwayBrowser/#/R-SSC-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Sus scrofa 15377 R-SSC-1237045 https://reactome.org/PathwayBrowser/#/R-SSC-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Sus scrofa 15377 R-SSC-1237047 https://reactome.org/PathwayBrowser/#/R-SSC-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Sus scrofa 15377 R-SSC-1237059 https://reactome.org/PathwayBrowser/#/R-SSC-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Sus scrofa 15377 R-SSC-1237081 https://reactome.org/PathwayBrowser/#/R-SSC-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Sus scrofa 15377 R-SSC-1237129 https://reactome.org/PathwayBrowser/#/R-SSC-1237129 Acireductone is created IEA Sus scrofa 15377 R-SSC-1247910 https://reactome.org/PathwayBrowser/#/R-SSC-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Sus scrofa 15377 R-SSC-1247935 https://reactome.org/PathwayBrowser/#/R-SSC-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Sus scrofa 15377 R-SSC-1363274 https://reactome.org/PathwayBrowser/#/R-SSC-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Sus scrofa 15377 R-SSC-1363276 https://reactome.org/PathwayBrowser/#/R-SSC-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Sus scrofa 15377 R-SSC-1369028 https://reactome.org/PathwayBrowser/#/R-SSC-1369028 ABCAs mediate lipid efflux IEA Sus scrofa 15377 R-SSC-1369052 https://reactome.org/PathwayBrowser/#/R-SSC-1369052 ABCAs mediate lipid influx IEA Sus scrofa 15377 R-SSC-1369065 https://reactome.org/PathwayBrowser/#/R-SSC-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Sus scrofa 15377 R-SSC-139906 https://reactome.org/PathwayBrowser/#/R-SSC-139906 Activation of BAD by calcineurin IEA Sus scrofa 15377 R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 15377 R-SSC-140359 https://reactome.org/PathwayBrowser/#/R-SSC-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Sus scrofa 15377 R-SSC-141186 https://reactome.org/PathwayBrowser/#/R-SSC-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Sus scrofa 15377 R-SSC-141200 https://reactome.org/PathwayBrowser/#/R-SSC-141200 MAOB:FAD oxidatively deaminates of PEA IEA Sus scrofa 15377 R-SSC-141202 https://reactome.org/PathwayBrowser/#/R-SSC-141202 MAOB:FAD oxidatively deaminates TYR IEA Sus scrofa 15377 R-SSC-141341 https://reactome.org/PathwayBrowser/#/R-SSC-141341 SMOX-3 oxidises SPN to SPM IEA Sus scrofa 15377 R-SSC-141348 https://reactome.org/PathwayBrowser/#/R-SSC-141348 PAO:FAD oxidises NASPM to PTCN IEA Sus scrofa 15377 R-SSC-141351 https://reactome.org/PathwayBrowser/#/R-SSC-141351 PAOX:FAD oxidises NASPN to SPM IEA Sus scrofa 15377 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 15377 R-SSC-1454916 https://reactome.org/PathwayBrowser/#/R-SSC-1454916 The ABCC family mediates organic anion transport IEA Sus scrofa 15377 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 15377 R-SSC-1467466 https://reactome.org/PathwayBrowser/#/R-SSC-1467466 ABCA4 mediates atRAL transport IEA Sus scrofa 15377 R-SSC-1474146 https://reactome.org/PathwayBrowser/#/R-SSC-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Sus scrofa 15377 R-SSC-1475017 https://reactome.org/PathwayBrowser/#/R-SSC-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Sus scrofa 15377 R-SSC-1475022 https://reactome.org/PathwayBrowser/#/R-SSC-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Sus scrofa 15377 R-SSC-1475025 https://reactome.org/PathwayBrowser/#/R-SSC-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Sus scrofa 15377 R-SSC-1475026 https://reactome.org/PathwayBrowser/#/R-SSC-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Sus scrofa 15377 R-SSC-1475028 https://reactome.org/PathwayBrowser/#/R-SSC-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Sus scrofa 15377 R-SSC-1475032 https://reactome.org/PathwayBrowser/#/R-SSC-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Sus scrofa 15377 R-SSC-1475435 https://reactome.org/PathwayBrowser/#/R-SSC-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Sus scrofa 15377 R-SSC-1475436 https://reactome.org/PathwayBrowser/#/R-SSC-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Sus scrofa 15377 R-SSC-1482543 https://reactome.org/PathwayBrowser/#/R-SSC-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Sus scrofa 15377 R-SSC-1482604 https://reactome.org/PathwayBrowser/#/R-SSC-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Sus scrofa 15377 R-SSC-1482612 https://reactome.org/PathwayBrowser/#/R-SSC-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 15377 R-SSC-1482656 https://reactome.org/PathwayBrowser/#/R-SSC-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Sus scrofa 15377 R-SSC-1482679 https://reactome.org/PathwayBrowser/#/R-SSC-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Sus scrofa 15377 R-SSC-1482685 https://reactome.org/PathwayBrowser/#/R-SSC-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 15377 R-SSC-1482745 https://reactome.org/PathwayBrowser/#/R-SSC-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Sus scrofa 15377 R-SSC-1482759 https://reactome.org/PathwayBrowser/#/R-SSC-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Sus scrofa 15377 R-SSC-1482771 https://reactome.org/PathwayBrowser/#/R-SSC-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Sus scrofa 15377 R-SSC-1482776 https://reactome.org/PathwayBrowser/#/R-SSC-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Sus scrofa 15377 R-SSC-1482777 https://reactome.org/PathwayBrowser/#/R-SSC-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Sus scrofa 15377 R-SSC-1482811 https://reactome.org/PathwayBrowser/#/R-SSC-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Sus scrofa 15377 R-SSC-1482816 https://reactome.org/PathwayBrowser/#/R-SSC-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Sus scrofa 15377 R-SSC-1482825 https://reactome.org/PathwayBrowser/#/R-SSC-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Sus scrofa 15377 R-SSC-1482828 https://reactome.org/PathwayBrowser/#/R-SSC-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Sus scrofa 15377 R-SSC-1482847 https://reactome.org/PathwayBrowser/#/R-SSC-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Sus scrofa 15377 R-SSC-1482856 https://reactome.org/PathwayBrowser/#/R-SSC-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Sus scrofa 15377 R-SSC-1482862 https://reactome.org/PathwayBrowser/#/R-SSC-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Sus scrofa 15377 R-SSC-1482868 https://reactome.org/PathwayBrowser/#/R-SSC-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Sus scrofa 15377 R-SSC-1482884 https://reactome.org/PathwayBrowser/#/R-SSC-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Sus scrofa 15377 R-SSC-1482887 https://reactome.org/PathwayBrowser/#/R-SSC-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Sus scrofa 15377 R-SSC-1482897 https://reactome.org/PathwayBrowser/#/R-SSC-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Sus scrofa 15377 R-SSC-1482900 https://reactome.org/PathwayBrowser/#/R-SSC-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Sus scrofa 15377 R-SSC-1482907 https://reactome.org/PathwayBrowser/#/R-SSC-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Sus scrofa 15377 R-SSC-1482920 https://reactome.org/PathwayBrowser/#/R-SSC-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Sus scrofa 15377 R-SSC-1482932 https://reactome.org/PathwayBrowser/#/R-SSC-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Sus scrofa 15377 R-SSC-1483096 https://reactome.org/PathwayBrowser/#/R-SSC-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Sus scrofa 15377 R-SSC-1483159 https://reactome.org/PathwayBrowser/#/R-SSC-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Sus scrofa 15377 R-SSC-1483182 https://reactome.org/PathwayBrowser/#/R-SSC-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Sus scrofa 15377 R-SSC-1483203 https://reactome.org/PathwayBrowser/#/R-SSC-1483203 PA is dephosphorylated to DAG by LPIN IEA Sus scrofa 15377 R-SSC-156526 https://reactome.org/PathwayBrowser/#/R-SSC-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Sus scrofa 15377 R-SSC-159425 https://reactome.org/PathwayBrowser/#/R-SSC-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 15377 R-SSC-159752 https://reactome.org/PathwayBrowser/#/R-SSC-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Sus scrofa 15377 R-SSC-159761 https://reactome.org/PathwayBrowser/#/R-SSC-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Sus scrofa 15377 R-SSC-159795 https://reactome.org/PathwayBrowser/#/R-SSC-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Sus scrofa 15377 R-SSC-159803 https://reactome.org/PathwayBrowser/#/R-SSC-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Sus scrofa 15377 R-SSC-159819 https://reactome.org/PathwayBrowser/#/R-SSC-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Sus scrofa 15377 R-SSC-159826 https://reactome.org/PathwayBrowser/#/R-SSC-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Sus scrofa 15377 R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa 15377 R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa 15377 R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa 15377 R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa 15377 R-SSC-1602399 https://reactome.org/PathwayBrowser/#/R-SSC-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Sus scrofa 15377 R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa 15377 R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa 15377 R-SSC-1605591 https://reactome.org/PathwayBrowser/#/R-SSC-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Sus scrofa 15377 R-SSC-1605595 https://reactome.org/PathwayBrowser/#/R-SSC-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Sus scrofa 15377 R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa 15377 R-SSC-1605632 https://reactome.org/PathwayBrowser/#/R-SSC-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Sus scrofa 15377 R-SSC-1605723 https://reactome.org/PathwayBrowser/#/R-SSC-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Sus scrofa 15377 R-SSC-1605724 https://reactome.org/PathwayBrowser/#/R-SSC-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Sus scrofa 15377 R-SSC-1605736 https://reactome.org/PathwayBrowser/#/R-SSC-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Sus scrofa 15377 R-SSC-1605768 https://reactome.org/PathwayBrowser/#/R-SSC-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Sus scrofa 15377 R-SSC-1605797 https://reactome.org/PathwayBrowser/#/R-SSC-1605797 SMPD1 hydrolyzes SPHM IEA Sus scrofa 15377 R-SSC-1606273 https://reactome.org/PathwayBrowser/#/R-SSC-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Sus scrofa 15377 R-SSC-1606288 https://reactome.org/PathwayBrowser/#/R-SSC-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Sus scrofa 15377 R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa 15377 R-SSC-1606564 https://reactome.org/PathwayBrowser/#/R-SSC-1606564 GALC hydrolyzes GalCer IEA Sus scrofa 15377 R-SSC-1606583 https://reactome.org/PathwayBrowser/#/R-SSC-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Sus scrofa 15377 R-SSC-1606602 https://reactome.org/PathwayBrowser/#/R-SSC-1606602 ASAH1 hydrolyzes ceramide IEA Sus scrofa 15377 R-SSC-1606789 https://reactome.org/PathwayBrowser/#/R-SSC-1606789 ARSB hydrolyses DS IEA Sus scrofa 15377 R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 15377 R-SSC-1606839 https://reactome.org/PathwayBrowser/#/R-SSC-1606839 ARSC hydrolyzes steroid sulfates IEA Sus scrofa 15377 R-SSC-1614524 https://reactome.org/PathwayBrowser/#/R-SSC-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Sus scrofa 15377 R-SSC-1614544 https://reactome.org/PathwayBrowser/#/R-SSC-1614544 Sulfite is oxidized to sulfate IEA Sus scrofa 15377 R-SSC-1614583 https://reactome.org/PathwayBrowser/#/R-SSC-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Sus scrofa 15377 R-SSC-1614605 https://reactome.org/PathwayBrowser/#/R-SSC-1614605 Persulfide sulfur is dioxygenated IEA Sus scrofa 15377 R-SSC-1614614 https://reactome.org/PathwayBrowser/#/R-SSC-1614614 Cysteine is degraded to serine and H2S IEA Sus scrofa 15377 R-SSC-1614631 https://reactome.org/PathwayBrowser/#/R-SSC-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Sus scrofa 15377 R-SSC-162425 https://reactome.org/PathwayBrowser/#/R-SSC-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Sus scrofa 15377 R-SSC-162729 https://reactome.org/PathwayBrowser/#/R-SSC-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Sus scrofa 15377 R-SSC-162857 https://reactome.org/PathwayBrowser/#/R-SSC-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Sus scrofa 15377 R-SSC-1630304 https://reactome.org/PathwayBrowser/#/R-SSC-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Sus scrofa 15377 R-SSC-1630306 https://reactome.org/PathwayBrowser/#/R-SSC-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Sus scrofa 15377 R-SSC-163120 https://reactome.org/PathwayBrowser/#/R-SSC-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Sus scrofa 15377 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa 15377 R-SSC-1638032 https://reactome.org/PathwayBrowser/#/R-SSC-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Sus scrofa 15377 R-SSC-1638053 https://reactome.org/PathwayBrowser/#/R-SSC-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Sus scrofa 15377 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa 15377 R-SSC-1640164 https://reactome.org/PathwayBrowser/#/R-SSC-1640164 ENPP7 hydrolyzes sphingomyelin IEA Sus scrofa 15377 R-SSC-164832 https://reactome.org/PathwayBrowser/#/R-SSC-164832 ATPase synthesizes ATP IEA Sus scrofa 15377 R-SSC-1655453 https://reactome.org/PathwayBrowser/#/R-SSC-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Sus scrofa 15377 R-SSC-1667005 https://reactome.org/PathwayBrowser/#/R-SSC-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Sus scrofa 15377 R-SSC-1675795 https://reactome.org/PathwayBrowser/#/R-SSC-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Sus scrofa 15377 R-SSC-1675824 https://reactome.org/PathwayBrowser/#/R-SSC-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Sus scrofa 15377 R-SSC-1675836 https://reactome.org/PathwayBrowser/#/R-SSC-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Sus scrofa 15377 R-SSC-1675949 https://reactome.org/PathwayBrowser/#/R-SSC-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Sus scrofa 15377 R-SSC-1675988 https://reactome.org/PathwayBrowser/#/R-SSC-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Sus scrofa 15377 R-SSC-1675994 https://reactome.org/PathwayBrowser/#/R-SSC-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Sus scrofa 15377 R-SSC-1676005 https://reactome.org/PathwayBrowser/#/R-SSC-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Sus scrofa 15377 R-SSC-1676020 https://reactome.org/PathwayBrowser/#/R-SSC-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Sus scrofa 15377 R-SSC-1676065 https://reactome.org/PathwayBrowser/#/R-SSC-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Sus scrofa 15377 R-SSC-1676105 https://reactome.org/PathwayBrowser/#/R-SSC-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Sus scrofa 15377 R-SSC-1676114 https://reactome.org/PathwayBrowser/#/R-SSC-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Sus scrofa 15377 R-SSC-1676124 https://reactome.org/PathwayBrowser/#/R-SSC-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Sus scrofa 15377 R-SSC-1676141 https://reactome.org/PathwayBrowser/#/R-SSC-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Sus scrofa 15377 R-SSC-1676149 https://reactome.org/PathwayBrowser/#/R-SSC-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Sus scrofa 15377 R-SSC-1676162 https://reactome.org/PathwayBrowser/#/R-SSC-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Sus scrofa 15377 R-SSC-1676164 https://reactome.org/PathwayBrowser/#/R-SSC-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Sus scrofa 15377 R-SSC-1676174 https://reactome.org/PathwayBrowser/#/R-SSC-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Sus scrofa 15377 R-SSC-1676177 https://reactome.org/PathwayBrowser/#/R-SSC-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Sus scrofa 15377 R-SSC-1676203 https://reactome.org/PathwayBrowser/#/R-SSC-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Sus scrofa 15377 R-SSC-1676204 https://reactome.org/PathwayBrowser/#/R-SSC-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Sus scrofa 15377 R-SSC-1678650 https://reactome.org/PathwayBrowser/#/R-SSC-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Sus scrofa 15377 R-SSC-1678708 https://reactome.org/PathwayBrowser/#/R-SSC-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Sus scrofa 15377 R-SSC-1678716 https://reactome.org/PathwayBrowser/#/R-SSC-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Sus scrofa 15377 R-SSC-1678742 https://reactome.org/PathwayBrowser/#/R-SSC-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Sus scrofa 15377 R-SSC-1678854 https://reactome.org/PathwayBrowser/#/R-SSC-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Sus scrofa 15377 R-SSC-170153 https://reactome.org/PathwayBrowser/#/R-SSC-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Sus scrofa 15377 R-SSC-170158 https://reactome.org/PathwayBrowser/#/R-SSC-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Sus scrofa 15377 R-SSC-170161 https://reactome.org/PathwayBrowser/#/R-SSC-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Sus scrofa 15377 R-SSC-173597 https://reactome.org/PathwayBrowser/#/R-SSC-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Sus scrofa 15377 R-SSC-173739 https://reactome.org/PathwayBrowser/#/R-SSC-173739 Spontaneous hydrolysis of C3 thioester IEA Sus scrofa 15377 R-SSC-174110 https://reactome.org/PathwayBrowser/#/R-SSC-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Sus scrofa 15377 R-SSC-174124 https://reactome.org/PathwayBrowser/#/R-SSC-174124 Dephosphorylation of phospho-Cdh1 IEA Sus scrofa 15377 R-SSC-174391 https://reactome.org/PathwayBrowser/#/R-SSC-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Sus scrofa 15377 R-SSC-174401 https://reactome.org/PathwayBrowser/#/R-SSC-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Sus scrofa 15377 R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa 15377 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa 15377 R-SSC-176606 https://reactome.org/PathwayBrowser/#/R-SSC-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Sus scrofa 15377 R-SSC-177923 https://reactome.org/PathwayBrowser/#/R-SSC-177923 Sustained activation of SRC kinase by SHP2 IEA Sus scrofa 15377 R-SSC-177924 https://reactome.org/PathwayBrowser/#/R-SSC-177924 Dephosphorylation of Gab1 by SHP2 IEA Sus scrofa 15377 R-SSC-177926 https://reactome.org/PathwayBrowser/#/R-SSC-177926 Dephosphorylation of PAG by SHP2 IEA Sus scrofa 15377 R-SSC-177935 https://reactome.org/PathwayBrowser/#/R-SSC-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Sus scrofa 15377 R-SSC-1793182 https://reactome.org/PathwayBrowser/#/R-SSC-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Sus scrofa 15377 R-SSC-1793186 https://reactome.org/PathwayBrowser/#/R-SSC-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Sus scrofa 15377 R-SSC-1793207 https://reactome.org/PathwayBrowser/#/R-SSC-1793207 ARSB hydrolyses C4S/C6S chains IEA Sus scrofa 15377 R-SSC-1793209 https://reactome.org/PathwayBrowser/#/R-SSC-1793209 HYAL1 hydrolyses Chondroitin chains IEA Sus scrofa 15377 R-SSC-1855154 https://reactome.org/PathwayBrowser/#/R-SSC-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 15377 R-SSC-1855159 https://reactome.org/PathwayBrowser/#/R-SSC-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Sus scrofa 15377 R-SSC-1855163 https://reactome.org/PathwayBrowser/#/R-SSC-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Sus scrofa 15377 R-SSC-1855165 https://reactome.org/PathwayBrowser/#/R-SSC-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 15377 R-SSC-1855166 https://reactome.org/PathwayBrowser/#/R-SSC-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Sus scrofa 15377 R-SSC-1855171 https://reactome.org/PathwayBrowser/#/R-SSC-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Sus scrofa 15377 R-SSC-1855174 https://reactome.org/PathwayBrowser/#/R-SSC-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Sus scrofa 15377 R-SSC-1855177 https://reactome.org/PathwayBrowser/#/R-SSC-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Sus scrofa 15377 R-SSC-1855180 https://reactome.org/PathwayBrowser/#/R-SSC-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Sus scrofa 15377 R-SSC-1855198 https://reactome.org/PathwayBrowser/#/R-SSC-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 15377 R-SSC-1855200 https://reactome.org/PathwayBrowser/#/R-SSC-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Sus scrofa 15377 R-SSC-1855202 https://reactome.org/PathwayBrowser/#/R-SSC-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Sus scrofa 15377 R-SSC-1855205 https://reactome.org/PathwayBrowser/#/R-SSC-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Sus scrofa 15377 R-SSC-1855208 https://reactome.org/PathwayBrowser/#/R-SSC-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Sus scrofa 15377 R-SSC-1855210 https://reactome.org/PathwayBrowser/#/R-SSC-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 15377 R-SSC-1855211 https://reactome.org/PathwayBrowser/#/R-SSC-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 15377 R-SSC-1855213 https://reactome.org/PathwayBrowser/#/R-SSC-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Sus scrofa 15377 R-SSC-1855214 https://reactome.org/PathwayBrowser/#/R-SSC-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Sus scrofa 15377 R-SSC-1855218 https://reactome.org/PathwayBrowser/#/R-SSC-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Sus scrofa 15377 R-SSC-1855219 https://reactome.org/PathwayBrowser/#/R-SSC-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 15377 R-SSC-1855221 https://reactome.org/PathwayBrowser/#/R-SSC-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Sus scrofa 15377 R-SSC-1855222 https://reactome.org/PathwayBrowser/#/R-SSC-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Sus scrofa 15377 R-SSC-1855225 https://reactome.org/PathwayBrowser/#/R-SSC-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Sus scrofa 15377 R-SSC-1855232 https://reactome.org/PathwayBrowser/#/R-SSC-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Sus scrofa 15377 R-SSC-1861788 https://reactome.org/PathwayBrowser/#/R-SSC-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Sus scrofa 15377 R-SSC-1861789 https://reactome.org/PathwayBrowser/#/R-SSC-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Sus scrofa 15377 R-SSC-188979 https://reactome.org/PathwayBrowser/#/R-SSC-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Sus scrofa 15377 R-SSC-189053 https://reactome.org/PathwayBrowser/#/R-SSC-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Sus scrofa 15377 R-SSC-189062 https://reactome.org/PathwayBrowser/#/R-SSC-189062 lactose + H2O => D-glucose + D-galactose IEA Sus scrofa 15377 R-SSC-189069 https://reactome.org/PathwayBrowser/#/R-SSC-189069 sucrose + H2O => glucose + fructose IEA Sus scrofa 15377 R-SSC-189102 https://reactome.org/PathwayBrowser/#/R-SSC-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Sus scrofa 15377 R-SSC-189398 https://reactome.org/PathwayBrowser/#/R-SSC-189398 HMOX1 dimer, HMOX2 cleave heme IEA Sus scrofa 15377 R-SSC-189406 https://reactome.org/PathwayBrowser/#/R-SSC-189406 4 PBGs bind to form HMB IEA Sus scrofa 15377 R-SSC-189421 https://reactome.org/PathwayBrowser/#/R-SSC-189421 CPO transforms COPRO3 to PPGEN9 IEA Sus scrofa 15377 R-SSC-189439 https://reactome.org/PathwayBrowser/#/R-SSC-189439 ALAD condenses 2 dALAs to form PBG IEA Sus scrofa 15377 R-SSC-189488 https://reactome.org/PathwayBrowser/#/R-SSC-189488 UROS transforms HMB to URO3 IEA Sus scrofa 15377 R-SSC-191101 https://reactome.org/PathwayBrowser/#/R-SSC-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Sus scrofa 15377 R-SSC-191108 https://reactome.org/PathwayBrowser/#/R-SSC-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Sus scrofa 15377 R-SSC-191114 https://reactome.org/PathwayBrowser/#/R-SSC-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Sus scrofa 15377 R-SSC-191116 https://reactome.org/PathwayBrowser/#/R-SSC-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Sus scrofa 15377 R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 15377 R-SSC-191323 https://reactome.org/PathwayBrowser/#/R-SSC-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Sus scrofa 15377 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 15377 R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 15377 R-SSC-191999 https://reactome.org/PathwayBrowser/#/R-SSC-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Sus scrofa 15377 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 15377 R-SSC-192054 https://reactome.org/PathwayBrowser/#/R-SSC-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Sus scrofa 15377 R-SSC-192061 https://reactome.org/PathwayBrowser/#/R-SSC-192061 CYP46A1 24-hydroxylates CHOL IEA Sus scrofa 15377 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 15377 R-SSC-192123 https://reactome.org/PathwayBrowser/#/R-SSC-192123 CYP27A1 27-hydroxylates CHOL IEA Sus scrofa 15377 R-SSC-192157 https://reactome.org/PathwayBrowser/#/R-SSC-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Sus scrofa 15377 R-SSC-192178 https://reactome.org/PathwayBrowser/#/R-SSC-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Sus scrofa 15377 R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 15377 R-SSC-192422 https://reactome.org/PathwayBrowser/#/R-SSC-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Sus scrofa 15377 R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 15377 R-SSC-192430 https://reactome.org/PathwayBrowser/#/R-SSC-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 15377 R-SSC-192434 https://reactome.org/PathwayBrowser/#/R-SSC-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Sus scrofa 15377 R-SSC-192475 https://reactome.org/PathwayBrowser/#/R-SSC-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Sus scrofa 15377 R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 15377 R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 15377 R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 15377 R-SSC-193068 https://reactome.org/PathwayBrowser/#/R-SSC-193068 CYP17A1 17-hydroxylates PREG IEA Sus scrofa 15377 R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 15377 R-SSC-193072 https://reactome.org/PathwayBrowser/#/R-SSC-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Sus scrofa 15377 R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 15377 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 15377 R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 15377 R-SSC-193362 https://reactome.org/PathwayBrowser/#/R-SSC-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Sus scrofa 15377 R-SSC-193385 https://reactome.org/PathwayBrowser/#/R-SSC-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Sus scrofa 15377 R-SSC-193393 https://reactome.org/PathwayBrowser/#/R-SSC-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Sus scrofa 15377 R-SSC-193460 https://reactome.org/PathwayBrowser/#/R-SSC-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Sus scrofa 15377 R-SSC-193709 https://reactome.org/PathwayBrowser/#/R-SSC-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Sus scrofa 15377 R-SSC-193711 https://reactome.org/PathwayBrowser/#/R-SSC-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 15377 R-SSC-193713 https://reactome.org/PathwayBrowser/#/R-SSC-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Sus scrofa 15377 R-SSC-193719 https://reactome.org/PathwayBrowser/#/R-SSC-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 15377 R-SSC-193727 https://reactome.org/PathwayBrowser/#/R-SSC-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 15377 R-SSC-193737 https://reactome.org/PathwayBrowser/#/R-SSC-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Sus scrofa 15377 R-SSC-193743 https://reactome.org/PathwayBrowser/#/R-SSC-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 15377 R-SSC-193766 https://reactome.org/PathwayBrowser/#/R-SSC-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 15377 R-SSC-193780 https://reactome.org/PathwayBrowser/#/R-SSC-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Sus scrofa 15377 R-SSC-193787 https://reactome.org/PathwayBrowser/#/R-SSC-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Sus scrofa 15377 R-SSC-193792 https://reactome.org/PathwayBrowser/#/R-SSC-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Sus scrofa 15377 R-SSC-193845 https://reactome.org/PathwayBrowser/#/R-SSC-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Sus scrofa 15377 R-SSC-193964 https://reactome.org/PathwayBrowser/#/R-SSC-193964 CYP21A2 21-hydroxylates PROG IEA Sus scrofa 15377 R-SSC-193965 https://reactome.org/PathwayBrowser/#/R-SSC-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Sus scrofa 15377 R-SSC-193981 https://reactome.org/PathwayBrowser/#/R-SSC-193981 CYP21A2 oxidises 17HPROG IEA Sus scrofa 15377 R-SSC-193995 https://reactome.org/PathwayBrowser/#/R-SSC-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Sus scrofa 15377 R-SSC-193997 https://reactome.org/PathwayBrowser/#/R-SSC-193997 CYP11B1 oxidises 11DCORT IEA Sus scrofa 15377 R-SSC-194017 https://reactome.org/PathwayBrowser/#/R-SSC-194017 CYP11B2 oxidises 11DCORST to CORST IEA Sus scrofa 15377 R-SSC-194641 https://reactome.org/PathwayBrowser/#/R-SSC-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15377 R-SSC-194669 https://reactome.org/PathwayBrowser/#/R-SSC-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15377 R-SSC-194678 https://reactome.org/PathwayBrowser/#/R-SSC-194678 CYP51A1 demethylates LNSOL IEA Sus scrofa 15377 R-SSC-195664 https://reactome.org/PathwayBrowser/#/R-SSC-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Sus scrofa 15377 R-SSC-196950 https://reactome.org/PathwayBrowser/#/R-SSC-196950 2xTRAP hydrolyzes FMN to RIB IEA Sus scrofa 15377 R-SSC-196955 https://reactome.org/PathwayBrowser/#/R-SSC-196955 2xENPP1 hydrolyzes FAD to FMN IEA Sus scrofa 15377 R-SSC-197271 https://reactome.org/PathwayBrowser/#/R-SSC-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Sus scrofa 15377 R-SSC-199456 https://reactome.org/PathwayBrowser/#/R-SSC-199456 PTEN dephosphorylates PIP3 IEA Sus scrofa 15377 R-SSC-199959 https://reactome.org/PathwayBrowser/#/R-SSC-199959 ERKs are inactivated by protein phosphatase 2A IEA Sus scrofa 15377 R-SSC-2002466 https://reactome.org/PathwayBrowser/#/R-SSC-2002466 Formation of allysine by LOX IEA Sus scrofa 15377 R-SSC-200661 https://reactome.org/PathwayBrowser/#/R-SSC-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Sus scrofa 15377 R-SSC-200740 https://reactome.org/PathwayBrowser/#/R-SSC-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Sus scrofa 15377 R-SSC-201035 https://reactome.org/PathwayBrowser/#/R-SSC-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Sus scrofa 15377 R-SSC-201790 https://reactome.org/PathwayBrowser/#/R-SSC-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Sus scrofa 15377 R-SSC-202214 https://reactome.org/PathwayBrowser/#/R-SSC-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Sus scrofa 15377 R-SSC-2022368 https://reactome.org/PathwayBrowser/#/R-SSC-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Sus scrofa 15377 R-SSC-202237 https://reactome.org/PathwayBrowser/#/R-SSC-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Sus scrofa 15377 R-SSC-2022378 https://reactome.org/PathwayBrowser/#/R-SSC-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Sus scrofa 15377 R-SSC-2022379 https://reactome.org/PathwayBrowser/#/R-SSC-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Sus scrofa 15377 R-SSC-2022381 https://reactome.org/PathwayBrowser/#/R-SSC-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 15377 R-SSC-2022383 https://reactome.org/PathwayBrowser/#/R-SSC-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 15377 R-SSC-2022396 https://reactome.org/PathwayBrowser/#/R-SSC-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Sus scrofa 15377 R-SSC-2022398 https://reactome.org/PathwayBrowser/#/R-SSC-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Sus scrofa 15377 R-SSC-2022399 https://reactome.org/PathwayBrowser/#/R-SSC-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Sus scrofa 15377 R-SSC-2022403 https://reactome.org/PathwayBrowser/#/R-SSC-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa 15377 R-SSC-2022405 https://reactome.org/PathwayBrowser/#/R-SSC-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 15377 R-SSC-2022411 https://reactome.org/PathwayBrowser/#/R-SSC-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 15377 R-SSC-2022412 https://reactome.org/PathwayBrowser/#/R-SSC-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa 15377 R-SSC-2022887 https://reactome.org/PathwayBrowser/#/R-SSC-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Sus scrofa 15377 R-SSC-2023971 https://reactome.org/PathwayBrowser/#/R-SSC-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 15377 R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 15377 R-SSC-202407 https://reactome.org/PathwayBrowser/#/R-SSC-202407 PLC-gamma1 hydrolyses PIP2 IEA Sus scrofa 15377 R-SSC-2029468 https://reactome.org/PathwayBrowser/#/R-SSC-2029468 Conversion of PA into DAG by PAP-1 IEA Sus scrofa 15377 R-SSC-2029471 https://reactome.org/PathwayBrowser/#/R-SSC-2029471 Hydrolysis of PC to PA by PLD IEA Sus scrofa 15377 R-SSC-2029475 https://reactome.org/PathwayBrowser/#/R-SSC-2029475 Production of AA by iPLA2 upon FCGR activation IEA Sus scrofa 15377 R-SSC-203797 https://reactome.org/PathwayBrowser/#/R-SSC-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Sus scrofa 15377 R-SSC-204169 https://reactome.org/PathwayBrowser/#/R-SSC-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Sus scrofa 15377 R-SSC-2046083 https://reactome.org/PathwayBrowser/#/R-SSC-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Sus scrofa 15377 R-SSC-2046084 https://reactome.org/PathwayBrowser/#/R-SSC-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Sus scrofa 15377 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa 15377 R-SSC-2046089 https://reactome.org/PathwayBrowser/#/R-SSC-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Sus scrofa 15377 R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 15377 R-SSC-2046092 https://reactome.org/PathwayBrowser/#/R-SSC-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Sus scrofa 15377 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa 15377 R-SSC-2046095 https://reactome.org/PathwayBrowser/#/R-SSC-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Sus scrofa 15377 R-SSC-2046096 https://reactome.org/PathwayBrowser/#/R-SSC-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Sus scrofa 15377 R-SSC-2046097 https://reactome.org/PathwayBrowser/#/R-SSC-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 15377 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa 15377 R-SSC-204662 https://reactome.org/PathwayBrowser/#/R-SSC-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Sus scrofa 15377 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 15377 R-SSC-2065357 https://reactome.org/PathwayBrowser/#/R-SSC-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa 15377 R-SSC-2066779 https://reactome.org/PathwayBrowser/#/R-SSC-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Sus scrofa 15377 R-SSC-2090037 https://reactome.org/PathwayBrowser/#/R-SSC-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Sus scrofa 15377 R-SSC-2090038 https://reactome.org/PathwayBrowser/#/R-SSC-2090038 NAGLU hydrolyses heparan chain(2) IEA Sus scrofa 15377 R-SSC-2090043 https://reactome.org/PathwayBrowser/#/R-SSC-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Sus scrofa 15377 R-SSC-2090079 https://reactome.org/PathwayBrowser/#/R-SSC-2090079 GLB1 hydrolyses linker chain(2) IEA Sus scrofa 15377 R-SSC-209055 https://reactome.org/PathwayBrowser/#/R-SSC-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Sus scrofa 15377 R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 15377 R-SSC-209845 https://reactome.org/PathwayBrowser/#/R-SSC-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Sus scrofa 15377 R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 15377 R-SSC-209891 https://reactome.org/PathwayBrowser/#/R-SSC-209891 Dopamine is oxidised to noradrenaline IEA Sus scrofa 15377 R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 15377 R-SSC-2105001 https://reactome.org/PathwayBrowser/#/R-SSC-2105001 HEXA cleaves the terminal GalNAc from DS IEA Sus scrofa 15377 R-SSC-211873 https://reactome.org/PathwayBrowser/#/R-SSC-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Sus scrofa 15377 R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 15377 R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa 15377 R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 15377 R-SSC-211904 https://reactome.org/PathwayBrowser/#/R-SSC-211904 CYP4F12 18-hydroxylates ARA IEA Sus scrofa 15377 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 15377 R-SSC-211919 https://reactome.org/PathwayBrowser/#/R-SSC-211919 CYP4F8 19-hydroxylates PGH2 IEA Sus scrofa 15377 R-SSC-211923 https://reactome.org/PathwayBrowser/#/R-SSC-211923 CYP26C1 4-hydroxylates 9cRA IEA Sus scrofa 15377 R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa 15377 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 15377 R-SSC-211948 https://reactome.org/PathwayBrowser/#/R-SSC-211948 CYP3A4 can N-demethylate loperamide IEA Sus scrofa 15377 R-SSC-211950 https://reactome.org/PathwayBrowser/#/R-SSC-211950 CYP24A1 24-hydroxylates CTL IEA Sus scrofa 15377 R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 15377 R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 15377 R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa 15377 R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa 15377 R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa 15377 R-SSC-211968 https://reactome.org/PathwayBrowser/#/R-SSC-211968 CYP2W1 oxidises INDOL IEA Sus scrofa 15377 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 15377 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 15377 R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa 15377 R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 15377 R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa 15377 R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 15377 R-SSC-2130725 https://reactome.org/PathwayBrowser/#/R-SSC-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Sus scrofa 15377 R-SSC-213175 https://reactome.org/PathwayBrowser/#/R-SSC-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Sus scrofa 15377 R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa 15377 R-SSC-2160492 https://reactome.org/PathwayBrowser/#/R-SSC-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Sus scrofa 15377 R-SSC-2160874 https://reactome.org/PathwayBrowser/#/R-SSC-2160874 HYAL1 hydrolyses (HA)50 IEA Sus scrofa 15377 R-SSC-2161187 https://reactome.org/PathwayBrowser/#/R-SSC-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Sus scrofa 15377 R-SSC-2161195 https://reactome.org/PathwayBrowser/#/R-SSC-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Sus scrofa 15377 R-SSC-2161745 https://reactome.org/PathwayBrowser/#/R-SSC-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Sus scrofa 15377 R-SSC-2161791 https://reactome.org/PathwayBrowser/#/R-SSC-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Sus scrofa 15377 R-SSC-2161792 https://reactome.org/PathwayBrowser/#/R-SSC-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Sus scrofa 15377 R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Sus scrofa 15377 R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa 15377 R-SSC-2161890 https://reactome.org/PathwayBrowser/#/R-SSC-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Sus scrofa 15377 R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Sus scrofa 15377 R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa 15377 R-SSC-2161951 https://reactome.org/PathwayBrowser/#/R-SSC-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Sus scrofa 15377 R-SSC-2161959 https://reactome.org/PathwayBrowser/#/R-SSC-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Sus scrofa 15377 R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Sus scrofa 15377 R-SSC-2161999 https://reactome.org/PathwayBrowser/#/R-SSC-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Sus scrofa 15377 R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa 15377 R-SSC-2162225 https://reactome.org/PathwayBrowser/#/R-SSC-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Sus scrofa 15377 R-SSC-2162226 https://reactome.org/PathwayBrowser/#/R-SSC-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Sus scrofa 15377 R-SSC-2162227 https://reactome.org/PathwayBrowser/#/R-SSC-2162227 GUSB tetramer hydrolyses (HA)2 IEA Sus scrofa 15377 R-SSC-216723 https://reactome.org/PathwayBrowser/#/R-SSC-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Sus scrofa 15377 R-SSC-216757 https://reactome.org/PathwayBrowser/#/R-SSC-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Sus scrofa 15377 R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 15377 R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 15377 R-SSC-2187401 https://reactome.org/PathwayBrowser/#/R-SSC-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Sus scrofa 15377 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 15377 R-SSC-2393939 https://reactome.org/PathwayBrowser/#/R-SSC-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 15377 R-SSC-2393954 https://reactome.org/PathwayBrowser/#/R-SSC-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 15377 R-SSC-2395340 https://reactome.org/PathwayBrowser/#/R-SSC-2395340 Formation of hydroxyallysine by LOX IEA Sus scrofa 15377 R-SSC-2395818 https://reactome.org/PathwayBrowser/#/R-SSC-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Sus scrofa 15377 R-SSC-2395849 https://reactome.org/PathwayBrowser/#/R-SSC-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 15377 R-SSC-2395869 https://reactome.org/PathwayBrowser/#/R-SSC-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 15377 R-SSC-2395872 https://reactome.org/PathwayBrowser/#/R-SSC-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Sus scrofa 15377 R-SSC-2395873 https://reactome.org/PathwayBrowser/#/R-SSC-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Sus scrofa 15377 R-SSC-2395876 https://reactome.org/PathwayBrowser/#/R-SSC-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 15377 R-SSC-2395879 https://reactome.org/PathwayBrowser/#/R-SSC-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 15377 R-SSC-2395965 https://reactome.org/PathwayBrowser/#/R-SSC-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Sus scrofa 15377 R-SSC-2408551 https://reactome.org/PathwayBrowser/#/R-SSC-2408551 SeMet is converted to AdoSeMet by MAT IEA Sus scrofa 15377 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 15377 R-SSC-2454118 https://reactome.org/PathwayBrowser/#/R-SSC-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Sus scrofa 15377 R-SSC-2465924 https://reactome.org/PathwayBrowser/#/R-SSC-2465924 OPN1LW binds 11cRAL IEA Sus scrofa 15377 R-SSC-2466085 https://reactome.org/PathwayBrowser/#/R-SSC-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Sus scrofa 15377 R-SSC-2509793 https://reactome.org/PathwayBrowser/#/R-SSC-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Sus scrofa 15377 R-SSC-2509816 https://reactome.org/PathwayBrowser/#/R-SSC-2509816 NUDT16 hydrolyses IDP to IMP IEA Sus scrofa 15377 R-SSC-2509827 https://reactome.org/PathwayBrowser/#/R-SSC-2509827 ITPA hydrolyses ITP to IMP IEA Sus scrofa 15377 R-SSC-2509831 https://reactome.org/PathwayBrowser/#/R-SSC-2509831 ITPA hydrolyses XTP to XMP IEA Sus scrofa 15377 R-SSC-2509838 https://reactome.org/PathwayBrowser/#/R-SSC-2509838 ITPA hydrolyses dITP to dIMP IEA Sus scrofa 15377 R-SSC-2529015 https://reactome.org/PathwayBrowser/#/R-SSC-2529015 Dephosphorylation of CK2-modified condensin I IEA Sus scrofa 15377 R-SSC-2584246 https://reactome.org/PathwayBrowser/#/R-SSC-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Sus scrofa 15377 R-SSC-2632521 https://reactome.org/PathwayBrowser/#/R-SSC-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Sus scrofa 15377 R-SSC-265783 https://reactome.org/PathwayBrowser/#/R-SSC-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Sus scrofa 15377 R-SSC-266012 https://reactome.org/PathwayBrowser/#/R-SSC-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Sus scrofa 15377 R-SSC-266046 https://reactome.org/PathwayBrowser/#/R-SSC-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Sus scrofa 15377 R-SSC-266051 https://reactome.org/PathwayBrowser/#/R-SSC-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Sus scrofa 15377 R-SSC-266072 https://reactome.org/PathwayBrowser/#/R-SSC-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Sus scrofa 15377 R-SSC-266082 https://reactome.org/PathwayBrowser/#/R-SSC-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Sus scrofa 15377 R-SSC-2730847 https://reactome.org/PathwayBrowser/#/R-SSC-2730847 Hydrolysis of PIP2 by PLCG IEA Sus scrofa 15377 R-SSC-2730849 https://reactome.org/PathwayBrowser/#/R-SSC-2730849 Calcineurin binds and dephosphorylates NFAT IEA Sus scrofa 15377 R-SSC-2855047 https://reactome.org/PathwayBrowser/#/R-SSC-2855047 Hydrolysis of internal thioester in C4b IEA Sus scrofa 15377 R-SSC-2995330 https://reactome.org/PathwayBrowser/#/R-SSC-2995330 COX10 transforms heme to heme O IEA Sus scrofa 15377 R-SSC-2995334 https://reactome.org/PathwayBrowser/#/R-SSC-2995334 COX15 transforms heme O to heme A IEA Sus scrofa 15377 R-SSC-2995388 https://reactome.org/PathwayBrowser/#/R-SSC-2995388 PP2A dephosphorylates BANF1 IEA Sus scrofa 15377 R-SSC-3002811 https://reactome.org/PathwayBrowser/#/R-SSC-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Sus scrofa 15377 R-SSC-3095901 https://reactome.org/PathwayBrowser/#/R-SSC-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Sus scrofa 15377 R-SSC-3204311 https://reactome.org/PathwayBrowser/#/R-SSC-3204311 AOX1 oxidises PXL to PDXate IEA Sus scrofa 15377 R-SSC-3215295 https://reactome.org/PathwayBrowser/#/R-SSC-3215295 USP7 deubiquitinates MDM2 IEA Sus scrofa 15377 R-SSC-3215310 https://reactome.org/PathwayBrowser/#/R-SSC-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Sus scrofa 15377 R-SSC-3247569 https://reactome.org/PathwayBrowser/#/R-SSC-3247569 PADI4 deiminates Histones IEA Sus scrofa 15377 R-SSC-3262512 https://reactome.org/PathwayBrowser/#/R-SSC-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Sus scrofa 15377 R-SSC-3266566 https://reactome.org/PathwayBrowser/#/R-SSC-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Sus scrofa 15377 R-SSC-3322995 https://reactome.org/PathwayBrowser/#/R-SSC-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Sus scrofa 15377 R-SSC-3323013 https://reactome.org/PathwayBrowser/#/R-SSC-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 15377 R-SSC-3341277 https://reactome.org/PathwayBrowser/#/R-SSC-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 15377 R-SSC-3341296 https://reactome.org/PathwayBrowser/#/R-SSC-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Sus scrofa 15377 R-SSC-3341343 https://reactome.org/PathwayBrowser/#/R-SSC-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Sus scrofa 15377 R-SSC-3341397 https://reactome.org/PathwayBrowser/#/R-SSC-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 15377 R-SSC-3343700 https://reactome.org/PathwayBrowser/#/R-SSC-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 15377 R-SSC-3371467 https://reactome.org/PathwayBrowser/#/R-SSC-3371467 SIRT1 deacetylates HSF1 IEA Sus scrofa 15377 R-SSC-350604 https://reactome.org/PathwayBrowser/#/R-SSC-350604 Agmatine + H2O <=> putrescine + urea IEA Sus scrofa 15377 R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa 15377 R-SSC-3640872 https://reactome.org/PathwayBrowser/#/R-SSC-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Sus scrofa 15377 R-SSC-3697882 https://reactome.org/PathwayBrowser/#/R-SSC-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Sus scrofa 15377 R-SSC-3697894 https://reactome.org/PathwayBrowser/#/R-SSC-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Sus scrofa 15377 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 15377 R-SSC-374909 https://reactome.org/PathwayBrowser/#/R-SSC-374909 Catabolism of Noradrenaline IEA Sus scrofa 15377 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa 15377 R-SSC-377643 https://reactome.org/PathwayBrowser/#/R-SSC-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Sus scrofa 15377 R-SSC-3777129 https://reactome.org/PathwayBrowser/#/R-SSC-3777129 HDAC3 containing complexes deacetylate histone IEA Sus scrofa 15377 R-SSC-3781011 https://reactome.org/PathwayBrowser/#/R-SSC-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Sus scrofa 15377 R-SSC-3781018 https://reactome.org/PathwayBrowser/#/R-SSC-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Sus scrofa 15377 R-SSC-3782637 https://reactome.org/PathwayBrowser/#/R-SSC-3782637 HDAC8 deacetylates histones IEA Sus scrofa 15377 R-SSC-3782655 https://reactome.org/PathwayBrowser/#/R-SSC-3782655 HDAC10 deacetylates histone IEA Sus scrofa 15377 R-SSC-379382 https://reactome.org/PathwayBrowser/#/R-SSC-379382 MAOA:FAD deaminates DA to DOPAC IEA Sus scrofa 15377 R-SSC-379395 https://reactome.org/PathwayBrowser/#/R-SSC-379395 MAOA:FAD deaminates 3MT to HVA IEA Sus scrofa 15377 R-SSC-380949 https://reactome.org/PathwayBrowser/#/R-SSC-380949 AMPK is dephosphorylated IEA Sus scrofa 15377 R-SSC-382553 https://reactome.org/PathwayBrowser/#/R-SSC-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Sus scrofa 15377 R-SSC-382560 https://reactome.org/PathwayBrowser/#/R-SSC-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Sus scrofa 15377 R-SSC-382575 https://reactome.org/PathwayBrowser/#/R-SSC-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Sus scrofa 15377 R-SSC-383190 https://reactome.org/PathwayBrowser/#/R-SSC-383190 HCO3- transport through ion channel IEA Sus scrofa 15377 R-SSC-389821 https://reactome.org/PathwayBrowser/#/R-SSC-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Sus scrofa 15377 R-SSC-389862 https://reactome.org/PathwayBrowser/#/R-SSC-389862 Conversion of glyoxylate to oxalate IEA Sus scrofa 15377 R-SSC-390304 https://reactome.org/PathwayBrowser/#/R-SSC-390304 acetyl-CoA + H2O => acetate + CoASH IEA Sus scrofa 15377 R-SSC-399998 https://reactome.org/PathwayBrowser/#/R-SSC-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Sus scrofa 15377 R-SSC-4084976 https://reactome.org/PathwayBrowser/#/R-SSC-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Sus scrofa 15377 R-SSC-4084989 https://reactome.org/PathwayBrowser/#/R-SSC-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Sus scrofa 15377 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 15377 R-SSC-4084999 https://reactome.org/PathwayBrowser/#/R-SSC-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 15377 R-SSC-4085021 https://reactome.org/PathwayBrowser/#/R-SSC-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Sus scrofa 15377 R-SSC-4085029 https://reactome.org/PathwayBrowser/#/R-SSC-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 15377 R-SSC-4086392 https://reactome.org/PathwayBrowser/#/R-SSC-4086392 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 15377 R-SSC-4088141 https://reactome.org/PathwayBrowser/#/R-SSC-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Sus scrofa 15377 R-SSC-4093339 https://reactome.org/PathwayBrowser/#/R-SSC-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Sus scrofa 15377 R-SSC-416559 https://reactome.org/PathwayBrowser/#/R-SSC-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Sus scrofa 15377 R-SSC-418553 https://reactome.org/PathwayBrowser/#/R-SSC-418553 cAMP degradation by Phosphodiesterases IEA Sus scrofa 15377 R-SSC-426043 https://reactome.org/PathwayBrowser/#/R-SSC-426043 2-AG hydrolysis to arachidonate by MAGL IEA Sus scrofa 15377 R-SSC-428205 https://reactome.org/PathwayBrowser/#/R-SSC-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Sus scrofa 15377 R-SSC-428231 https://reactome.org/PathwayBrowser/#/R-SSC-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Sus scrofa 15377 R-SSC-428259 https://reactome.org/PathwayBrowser/#/R-SSC-428259 DEGS1 dehydrogenates dihydroceramide IEA Sus scrofa 15377 R-SSC-428260 https://reactome.org/PathwayBrowser/#/R-SSC-428260 DEGS2 oxygenates dihydroceramide IEA Sus scrofa 15377 R-SSC-428262 https://reactome.org/PathwayBrowser/#/R-SSC-428262 ACER3 hydrolyzes phytoceramide IEA Sus scrofa 15377 R-SSC-428664 https://reactome.org/PathwayBrowser/#/R-SSC-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Sus scrofa 15377 R-SSC-428690 https://reactome.org/PathwayBrowser/#/R-SSC-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Sus scrofa 15377 R-SSC-428696 https://reactome.org/PathwayBrowser/#/R-SSC-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Sus scrofa 15377 R-SSC-429157 https://reactome.org/PathwayBrowser/#/R-SSC-429157 ABCC4 accumulation of dense granule contents IEA Sus scrofa 15377 R-SSC-429860 https://reactome.org/PathwayBrowser/#/R-SSC-429860 DCP1-DCP2 complex decaps mRNA IEA Sus scrofa 15377 R-SSC-429955 https://reactome.org/PathwayBrowser/#/R-SSC-429955 CCR4-NOT complex deadenylates mRNA IEA Sus scrofa 15377 R-SSC-429961 https://reactome.org/PathwayBrowser/#/R-SSC-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Sus scrofa 15377 R-SSC-429992 https://reactome.org/PathwayBrowser/#/R-SSC-429992 PARN deadenylates mRNA IEA Sus scrofa 15377 R-SSC-430021 https://reactome.org/PathwayBrowser/#/R-SSC-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Sus scrofa 15377 R-SSC-430028 https://reactome.org/PathwayBrowser/#/R-SSC-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Sus scrofa 15377 R-SSC-432010 https://reactome.org/PathwayBrowser/#/R-SSC-432010 Aquaporin-1 passively transports water into cell IEA Sus scrofa 15377 R-SSC-432054 https://reactome.org/PathwayBrowser/#/R-SSC-432054 Aquaporin-1 passively transports water out of cell IEA Sus scrofa 15377 R-SSC-432065 https://reactome.org/PathwayBrowser/#/R-SSC-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Sus scrofa 15377 R-SSC-432067 https://reactome.org/PathwayBrowser/#/R-SSC-432067 Aquaporin-4 passively transports water out of cell IEA Sus scrofa 15377 R-SSC-4419948 https://reactome.org/PathwayBrowser/#/R-SSC-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Sus scrofa 15377 R-SSC-445714 https://reactome.org/PathwayBrowser/#/R-SSC-445714 Aquaporin-3 passively transports water out of cell IEA Sus scrofa 15377 R-SSC-446200 https://reactome.org/PathwayBrowser/#/R-SSC-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Sus scrofa 15377 R-SSC-449937 https://reactome.org/PathwayBrowser/#/R-SSC-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Sus scrofa 15377 R-SSC-452036 https://reactome.org/PathwayBrowser/#/R-SSC-452036 arginine + H2O => ornithine + urea [ARG2] IEA Sus scrofa 15377 R-SSC-4551451 https://reactome.org/PathwayBrowser/#/R-SSC-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Sus scrofa 15377 R-SSC-4641236 https://reactome.org/PathwayBrowser/#/R-SSC-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Sus scrofa 15377 R-SSC-504054 https://reactome.org/PathwayBrowser/#/R-SSC-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Sus scrofa 15377 R-SSC-507868 https://reactome.org/PathwayBrowser/#/R-SSC-507868 Aquaporins passively transport water into cells IEA Sus scrofa 15377 R-SSC-507870 https://reactome.org/PathwayBrowser/#/R-SSC-507870 Aquaporins passively transport water out of cells IEA Sus scrofa 15377 R-SSC-508308 https://reactome.org/PathwayBrowser/#/R-SSC-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Sus scrofa 15377 R-SSC-5221130 https://reactome.org/PathwayBrowser/#/R-SSC-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Sus scrofa 15377 R-SSC-5223313 https://reactome.org/PathwayBrowser/#/R-SSC-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Sus scrofa 15377 R-SSC-5223317 https://reactome.org/PathwayBrowser/#/R-SSC-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Sus scrofa 15377 R-SSC-5251955 https://reactome.org/PathwayBrowser/#/R-SSC-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Sus scrofa 15377 R-SSC-5251959 https://reactome.org/PathwayBrowser/#/R-SSC-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Sus scrofa 15377 R-SSC-5251989 https://reactome.org/PathwayBrowser/#/R-SSC-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Sus scrofa 15377 R-SSC-5362459 https://reactome.org/PathwayBrowser/#/R-SSC-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Sus scrofa 15377 R-SSC-5362522 https://reactome.org/PathwayBrowser/#/R-SSC-5362522 ALDHs oxidise atRAL to atRA IEA Sus scrofa 15377 R-SSC-5362525 https://reactome.org/PathwayBrowser/#/R-SSC-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Sus scrofa 15377 R-SSC-5423647 https://reactome.org/PathwayBrowser/#/R-SSC-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Sus scrofa 15377 R-SSC-5423664 https://reactome.org/PathwayBrowser/#/R-SSC-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Sus scrofa 15377 R-SSC-5423672 https://reactome.org/PathwayBrowser/#/R-SSC-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Sus scrofa 15377 R-SSC-5423678 https://reactome.org/PathwayBrowser/#/R-SSC-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Sus scrofa 15377 R-SSC-5433072 https://reactome.org/PathwayBrowser/#/R-SSC-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Sus scrofa 15377 R-SSC-5433074 https://reactome.org/PathwayBrowser/#/R-SSC-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Sus scrofa 15377 R-SSC-548843 https://reactome.org/PathwayBrowser/#/R-SSC-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Sus scrofa 15377 R-SSC-5602295 https://reactome.org/PathwayBrowser/#/R-SSC-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Sus scrofa 15377 R-SSC-5603114 https://reactome.org/PathwayBrowser/#/R-SSC-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Sus scrofa 15377 R-SSC-5607735 https://reactome.org/PathwayBrowser/#/R-SSC-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Sus scrofa 15377 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 15377 R-SSC-5623513 https://reactome.org/PathwayBrowser/#/R-SSC-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Sus scrofa 15377 R-SSC-5628905 https://reactome.org/PathwayBrowser/#/R-SSC-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Sus scrofa 15377 R-SSC-5631885 https://reactome.org/PathwayBrowser/#/R-SSC-5631885 PRDX1 overoxidizes IEA Sus scrofa 15377 R-SSC-5649705 https://reactome.org/PathwayBrowser/#/R-SSC-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Sus scrofa 15377 R-SSC-5651828 https://reactome.org/PathwayBrowser/#/R-SSC-5651828 PARG dePARylates PARP1,PARP2 IEA Sus scrofa 15377 R-SSC-5653770 https://reactome.org/PathwayBrowser/#/R-SSC-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa 15377 R-SSC-5653786 https://reactome.org/PathwayBrowser/#/R-SSC-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Sus scrofa 15377 R-SSC-5659861 https://reactome.org/PathwayBrowser/#/R-SSC-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Sus scrofa 15377 R-SSC-5662692 https://reactome.org/PathwayBrowser/#/R-SSC-5662692 Dopa is oxidized to dopaquinone by TYR IEA Sus scrofa 15377 R-SSC-5665809 https://reactome.org/PathwayBrowser/#/R-SSC-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Sus scrofa 15377 R-SSC-5672957 https://reactome.org/PathwayBrowser/#/R-SSC-5672957 PP2A dephosphorylates KSR1 IEA Sus scrofa 15377 R-SSC-5672961 https://reactome.org/PathwayBrowser/#/R-SSC-5672961 PP2A dephosphorylates inactive RAFs IEA Sus scrofa 15377 R-SSC-5675373 https://reactome.org/PathwayBrowser/#/R-SSC-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Sus scrofa 15377 R-SSC-5675376 https://reactome.org/PathwayBrowser/#/R-SSC-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Sus scrofa 15377 R-SSC-5675431 https://reactome.org/PathwayBrowser/#/R-SSC-5675431 PP2A dephosphorylates RAF1 IEA Sus scrofa 15377 R-SSC-5675433 https://reactome.org/PathwayBrowser/#/R-SSC-5675433 PP5 dephosphorylates RAF1 S338 IEA Sus scrofa 15377 R-SSC-5676637 https://reactome.org/PathwayBrowser/#/R-SSC-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Sus scrofa 15377 R-SSC-5678327 https://reactome.org/PathwayBrowser/#/R-SSC-5678327 MIOX oxidises Ins to GlcA IEA Sus scrofa 15377 R-SSC-5678706 https://reactome.org/PathwayBrowser/#/R-SSC-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Sus scrofa 15377 R-SSC-5678863 https://reactome.org/PathwayBrowser/#/R-SSC-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Sus scrofa 15377 R-SSC-5679041 https://reactome.org/PathwayBrowser/#/R-SSC-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 15377 R-SSC-5682285 https://reactome.org/PathwayBrowser/#/R-SSC-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Sus scrofa 15377 R-SSC-5683405 https://reactome.org/PathwayBrowser/#/R-SSC-5683405 PPP5C dephosphorylates TP53BP1 IEA Sus scrofa 15377 R-SSC-5683714 https://reactome.org/PathwayBrowser/#/R-SSC-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Sus scrofa 15377 R-SSC-5683967 https://reactome.org/PathwayBrowser/#/R-SSC-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Sus scrofa 15377 R-SSC-5684864 https://reactome.org/PathwayBrowser/#/R-SSC-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Sus scrofa 15377 R-SSC-5685902 https://reactome.org/PathwayBrowser/#/R-SSC-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Sus scrofa 15377 R-SSC-5685994 https://reactome.org/PathwayBrowser/#/R-SSC-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Sus scrofa 15377 R-SSC-5687464 https://reactome.org/PathwayBrowser/#/R-SSC-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Sus scrofa 15377 R-SSC-5687664 https://reactome.org/PathwayBrowser/#/R-SSC-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Sus scrofa 15377 R-SSC-5687758 https://reactome.org/PathwayBrowser/#/R-SSC-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Sus scrofa 15377 R-SSC-5688797 https://reactome.org/PathwayBrowser/#/R-SSC-5688797 ATXN3 family cleave Ub chains IEA Sus scrofa 15377 R-SSC-5689000 https://reactome.org/PathwayBrowser/#/R-SSC-5689000 AADAC deacetylates PHEN IEA Sus scrofa 15377 R-SSC-5689950 https://reactome.org/PathwayBrowser/#/R-SSC-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Sus scrofa 15377 R-SSC-5689973 https://reactome.org/PathwayBrowser/#/R-SSC-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Sus scrofa 15377 R-SSC-5690042 https://reactome.org/PathwayBrowser/#/R-SSC-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 15377 R-SSC-5690043 https://reactome.org/PathwayBrowser/#/R-SSC-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 15377 R-SSC-5690046 https://reactome.org/PathwayBrowser/#/R-SSC-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Sus scrofa 15377 R-SSC-5690066 https://reactome.org/PathwayBrowser/#/R-SSC-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 15377 R-SSC-5690080 https://reactome.org/PathwayBrowser/#/R-SSC-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Sus scrofa 15377 R-SSC-5690152 https://reactome.org/PathwayBrowser/#/R-SSC-5690152 USP5 cleaves polyubiquitin IEA Sus scrofa 15377 R-SSC-5690157 https://reactome.org/PathwayBrowser/#/R-SSC-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Sus scrofa 15377 R-SSC-5690159 https://reactome.org/PathwayBrowser/#/R-SSC-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Sus scrofa 15377 R-SSC-5690196 https://reactome.org/PathwayBrowser/#/R-SSC-5690196 USP8 deubiquitinates RNF128 IEA Sus scrofa 15377 R-SSC-5690319 https://reactome.org/PathwayBrowser/#/R-SSC-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Sus scrofa 15377 R-SSC-5690517 https://reactome.org/PathwayBrowser/#/R-SSC-5690517 PPT1 hydrolyses palmitoylated proteins IEA Sus scrofa 15377 R-SSC-5690565 https://reactome.org/PathwayBrowser/#/R-SSC-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15377 R-SSC-5690759 https://reactome.org/PathwayBrowser/#/R-SSC-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Sus scrofa 15377 R-SSC-5690790 https://reactome.org/PathwayBrowser/#/R-SSC-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Sus scrofa 15377 R-SSC-5690808 https://reactome.org/PathwayBrowser/#/R-SSC-5690808 UCHL3, SENP8 cleave NEDD8 IEA Sus scrofa 15377 R-SSC-5690856 https://reactome.org/PathwayBrowser/#/R-SSC-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Sus scrofa 15377 R-SSC-5690870 https://reactome.org/PathwayBrowser/#/R-SSC-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Sus scrofa 15377 R-SSC-5691381 https://reactome.org/PathwayBrowser/#/R-SSC-5691381 MYSM1 deubiquitinates Histone H2A IEA Sus scrofa 15377 R-SSC-5691411 https://reactome.org/PathwayBrowser/#/R-SSC-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Sus scrofa 15377 R-SSC-5691439 https://reactome.org/PathwayBrowser/#/R-SSC-5691439 BRISC complex deubiquitinates NLRP3 IEA Sus scrofa 15377 R-SSC-5691507 https://reactome.org/PathwayBrowser/#/R-SSC-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Sus scrofa 15377 R-SSC-5691512 https://reactome.org/PathwayBrowser/#/R-SSC-5691512 APEH hydrolyses NAc-Ser-protein IEA Sus scrofa 15377 R-SSC-5692261 https://reactome.org/PathwayBrowser/#/R-SSC-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Sus scrofa 15377 R-SSC-5692283 https://reactome.org/PathwayBrowser/#/R-SSC-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Sus scrofa 15377 R-SSC-5692462 https://reactome.org/PathwayBrowser/#/R-SSC-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Sus scrofa 15377 R-SSC-5692480 https://reactome.org/PathwayBrowser/#/R-SSC-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Sus scrofa 15377 R-SSC-5692754 https://reactome.org/PathwayBrowser/#/R-SSC-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Sus scrofa 15377 R-SSC-5693153 https://reactome.org/PathwayBrowser/#/R-SSC-5693153 PPM1K dephosphorylates p-BCKDH IEA Sus scrofa 15377 R-SSC-5693346 https://reactome.org/PathwayBrowser/#/R-SSC-5693346 CECRI deaminates Ade-Rib to Ino IEA Sus scrofa 15377 R-SSC-5693608 https://reactome.org/PathwayBrowser/#/R-SSC-5693608 Initial resection of double-strand break ends IEA Sus scrofa 15377 R-SSC-5693691 https://reactome.org/PathwayBrowser/#/R-SSC-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Sus scrofa 15377 R-SSC-5693724 https://reactome.org/PathwayBrowser/#/R-SSC-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Sus scrofa 15377 R-SSC-5693742 https://reactome.org/PathwayBrowser/#/R-SSC-5693742 FAAH hydrolyses AEA to AA and ETA IEA Sus scrofa 15377 R-SSC-5693761 https://reactome.org/PathwayBrowser/#/R-SSC-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Sus scrofa 15377 R-SSC-5693807 https://reactome.org/PathwayBrowser/#/R-SSC-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Sus scrofa 15377 R-SSC-5694077 https://reactome.org/PathwayBrowser/#/R-SSC-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Sus scrofa 15377 R-SSC-5694109 https://reactome.org/PathwayBrowser/#/R-SSC-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Sus scrofa 15377 R-SSC-5694126 https://reactome.org/PathwayBrowser/#/R-SSC-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Sus scrofa 15377 R-SSC-5694137 https://reactome.org/PathwayBrowser/#/R-SSC-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Sus scrofa 15377 R-SSC-5694421 https://reactome.org/PathwayBrowser/#/R-SSC-5694421 PP6 dephosphorylates SEC24 IEA Sus scrofa 15377 R-SSC-5694462 https://reactome.org/PathwayBrowser/#/R-SSC-5694462 ABHD6,12 hydrolyse 3AG IEA Sus scrofa 15377 R-SSC-5694485 https://reactome.org/PathwayBrowser/#/R-SSC-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Sus scrofa 15377 R-SSC-5694563 https://reactome.org/PathwayBrowser/#/R-SSC-5694563 ABHD10 hydrolyses MPAG IEA Sus scrofa 15377 R-SSC-5694583 https://reactome.org/PathwayBrowser/#/R-SSC-5694583 ABHD4 hydrolyses NAPE IEA Sus scrofa 15377 R-SSC-5695964 https://reactome.org/PathwayBrowser/#/R-SSC-5695964 ABHD14B hydrolyses PNPB IEA Sus scrofa 15377 R-SSC-5696049 https://reactome.org/PathwayBrowser/#/R-SSC-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 15377 R-SSC-5696080 https://reactome.org/PathwayBrowser/#/R-SSC-5696080 ALDH3B1 oxidises HXAL to PALM IEA Sus scrofa 15377 R-SSC-5696091 https://reactome.org/PathwayBrowser/#/R-SSC-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Sus scrofa 15377 R-SSC-5696101 https://reactome.org/PathwayBrowser/#/R-SSC-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Sus scrofa 15377 R-SSC-5696119 https://reactome.org/PathwayBrowser/#/R-SSC-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Sus scrofa 15377 R-SSC-5696131 https://reactome.org/PathwayBrowser/#/R-SSC-5696131 AOC1 deaminates Hist IEA Sus scrofa 15377 R-SSC-5696146 https://reactome.org/PathwayBrowser/#/R-SSC-5696146 AOC2 deaminates TYR IEA Sus scrofa 15377 R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa 15377 R-SSC-5696197 https://reactome.org/PathwayBrowser/#/R-SSC-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Sus scrofa 15377 R-SSC-5696230 https://reactome.org/PathwayBrowser/#/R-SSC-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Sus scrofa 15377 R-SSC-5696365 https://reactome.org/PathwayBrowser/#/R-SSC-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Sus scrofa 15377 R-SSC-5696408 https://reactome.org/PathwayBrowser/#/R-SSC-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Sus scrofa 15377 R-SSC-5696415 https://reactome.org/PathwayBrowser/#/R-SSC-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Sus scrofa 15377 R-SSC-5696465 https://reactome.org/PathwayBrowser/#/R-SSC-5696465 USP45 deubiquitinates ERCC1 IEA Sus scrofa 15377 R-SSC-5696534 https://reactome.org/PathwayBrowser/#/R-SSC-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Sus scrofa 15377 R-SSC-5696564 https://reactome.org/PathwayBrowser/#/R-SSC-5696564 USP25 deubiquitinates DDX58 IEA Sus scrofa 15377 R-SSC-5696600 https://reactome.org/PathwayBrowser/#/R-SSC-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Sus scrofa 15377 R-SSC-5696605 https://reactome.org/PathwayBrowser/#/R-SSC-5696605 USP12, USP26 deubiquitinate AR IEA Sus scrofa 15377 R-SSC-5696627 https://reactome.org/PathwayBrowser/#/R-SSC-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Sus scrofa 15377 R-SSC-5696872 https://reactome.org/PathwayBrowser/#/R-SSC-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Sus scrofa 15377 R-SSC-5696914 https://reactome.org/PathwayBrowser/#/R-SSC-5696914 USP28 deubiquitinates CLSPN and MYC IEA Sus scrofa 15377 R-SSC-5696945 https://reactome.org/PathwayBrowser/#/R-SSC-5696945 USP33 deubiquitinates CCP110,ARRB IEA Sus scrofa 15377 R-SSC-5696947 https://reactome.org/PathwayBrowser/#/R-SSC-5696947 USP47 deubiquitinates POLB IEA Sus scrofa 15377 R-SSC-5696958 https://reactome.org/PathwayBrowser/#/R-SSC-5696958 USP44 deubiquitinates CDC20 IEA Sus scrofa 15377 R-SSC-5696960 https://reactome.org/PathwayBrowser/#/R-SSC-5696960 USP49 deubiquitinates H2B IEA Sus scrofa 15377 R-SSC-5696968 https://reactome.org/PathwayBrowser/#/R-SSC-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Sus scrofa 15377 R-SSC-5696997 https://reactome.org/PathwayBrowser/#/R-SSC-5696997 USP24 deubiquitinates DDB2 IEA Sus scrofa 15377 R-SSC-5697009 https://reactome.org/PathwayBrowser/#/R-SSC-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Sus scrofa 15377 R-SSC-6781764 https://reactome.org/PathwayBrowser/#/R-SSC-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Sus scrofa 15377 R-SSC-6781779 https://reactome.org/PathwayBrowser/#/R-SSC-6781779 USP13 deubiquitinates BECN1,USP10 IEA Sus scrofa 15377 R-SSC-6781814 https://reactome.org/PathwayBrowser/#/R-SSC-6781814 USP19 deubiquitinates RNF123 IEA Sus scrofa 15377 R-SSC-6781897 https://reactome.org/PathwayBrowser/#/R-SSC-6781897 USP11 deubiquitinates NFKBIA IEA Sus scrofa 15377 R-SSC-6782069 https://reactome.org/PathwayBrowser/#/R-SSC-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Sus scrofa 15377 R-SSC-6782106 https://reactome.org/PathwayBrowser/#/R-SSC-6782106 USP10 deubiquitinates SNX3, CFTR IEA Sus scrofa 15377 R-SSC-6782628 https://reactome.org/PathwayBrowser/#/R-SSC-6782628 USP8 deubiquitinates STAM2:HGS IEA Sus scrofa 15377 R-SSC-6782820 https://reactome.org/PathwayBrowser/#/R-SSC-6782820 USP17 deubiquitinates SUDS3 IEA Sus scrofa 15377 R-SSC-6783177 https://reactome.org/PathwayBrowser/#/R-SSC-6783177 USP21 deubiquitinates GATA3,IL33 IEA Sus scrofa 15377 R-SSC-6783221 https://reactome.org/PathwayBrowser/#/R-SSC-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Sus scrofa 15377 R-SSC-6784959 https://reactome.org/PathwayBrowser/#/R-SSC-6784959 BPHL hydrolyses VACV to ACV IEA Sus scrofa 15377 R-SSC-6786190 https://reactome.org/PathwayBrowser/#/R-SSC-6786190 CMBL hydrolyses OM to OLMS IEA Sus scrofa 15377 R-SSC-6786239 https://reactome.org/PathwayBrowser/#/R-SSC-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Sus scrofa 15377 R-SSC-6786421 https://reactome.org/PathwayBrowser/#/R-SSC-6786421 CHIA hydrolyses chitin IEA Sus scrofa 15377 R-SSC-6786650 https://reactome.org/PathwayBrowser/#/R-SSC-6786650 DDHD1,2 hydrolyse PA IEA Sus scrofa 15377 R-SSC-6786652 https://reactome.org/PathwayBrowser/#/R-SSC-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Sus scrofa 15377 R-SSC-6787632 https://reactome.org/PathwayBrowser/#/R-SSC-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Sus scrofa 15377 R-SSC-6788295 https://reactome.org/PathwayBrowser/#/R-SSC-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Sus scrofa 15377 R-SSC-6788912 https://reactome.org/PathwayBrowser/#/R-SSC-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Sus scrofa 15377 R-SSC-6789031 https://reactome.org/PathwayBrowser/#/R-SSC-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 15377 R-SSC-6789126 https://reactome.org/PathwayBrowser/#/R-SSC-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 15377 R-SSC-6789310 https://reactome.org/PathwayBrowser/#/R-SSC-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Sus scrofa 15377 R-SSC-6792445 https://reactome.org/PathwayBrowser/#/R-SSC-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Sus scrofa 15377 R-SSC-6792863 https://reactome.org/PathwayBrowser/#/R-SSC-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Sus scrofa 15377 R-SSC-6797627 https://reactome.org/PathwayBrowser/#/R-SSC-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Sus scrofa 15377 R-SSC-6797630 https://reactome.org/PathwayBrowser/#/R-SSC-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Sus scrofa 15377 R-SSC-6797653 https://reactome.org/PathwayBrowser/#/R-SSC-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Sus scrofa 15377 R-SSC-6797913 https://reactome.org/PathwayBrowser/#/R-SSC-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Sus scrofa 15377 R-SSC-6797955 https://reactome.org/PathwayBrowser/#/R-SSC-6797955 ALDH7A1 oxidises BETALD to BET IEA Sus scrofa 15377 R-SSC-6799545 https://reactome.org/PathwayBrowser/#/R-SSC-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Sus scrofa 15377 R-SSC-6799581 https://reactome.org/PathwayBrowser/#/R-SSC-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Sus scrofa 15377 R-SSC-6799604 https://reactome.org/PathwayBrowser/#/R-SSC-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Sus scrofa 15377 R-SSC-6799695 https://reactome.org/PathwayBrowser/#/R-SSC-6799695 GPX5,6 reduce H2O2 to H2O IEA Sus scrofa 15377 R-SSC-6799977 https://reactome.org/PathwayBrowser/#/R-SSC-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Sus scrofa 15377 R-SSC-6800198 https://reactome.org/PathwayBrowser/#/R-SSC-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Sus scrofa 15377 R-SSC-6800200 https://reactome.org/PathwayBrowser/#/R-SSC-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Sus scrofa 15377 R-SSC-6800299 https://reactome.org/PathwayBrowser/#/R-SSC-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Sus scrofa 15377 R-SSC-6801462 https://reactome.org/PathwayBrowser/#/R-SSC-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Sus scrofa 15377 R-SSC-6803545 https://reactome.org/PathwayBrowser/#/R-SSC-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Sus scrofa 15377 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 15377 R-SSC-6803789 https://reactome.org/PathwayBrowser/#/R-SSC-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Sus scrofa 15377 R-SSC-6805650 https://reactome.org/PathwayBrowser/#/R-SSC-6805650 MTA2-NuRD complex deacetylates TP53 IEA Sus scrofa 15377 R-SSC-6807027 https://reactome.org/PathwayBrowser/#/R-SSC-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Sus scrofa 15377 R-SSC-6807053 https://reactome.org/PathwayBrowser/#/R-SSC-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Sus scrofa 15377 R-SSC-6807118 https://reactome.org/PathwayBrowser/#/R-SSC-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Sus scrofa 15377 R-SSC-6807206 https://reactome.org/PathwayBrowser/#/R-SSC-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Sus scrofa 15377 R-SSC-6807214 https://reactome.org/PathwayBrowser/#/R-SSC-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Sus scrofa 15377 R-SSC-6808464 https://reactome.org/PathwayBrowser/#/R-SSC-6808464 ALDH3B2 oxidises HXAL to PALM IEA Sus scrofa 15377 R-SSC-6808487 https://reactome.org/PathwayBrowser/#/R-SSC-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 15377 R-SSC-6808496 https://reactome.org/PathwayBrowser/#/R-SSC-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 15377 R-SSC-6809263 https://reactome.org/PathwayBrowser/#/R-SSC-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Sus scrofa 15377 R-SSC-6809287 https://reactome.org/PathwayBrowser/#/R-SSC-6809287 NUDT12 hydrolyses NADH to NMNH IEA Sus scrofa 15377 R-SSC-6809320 https://reactome.org/PathwayBrowser/#/R-SSC-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Sus scrofa 15377 R-SSC-6809325 https://reactome.org/PathwayBrowser/#/R-SSC-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Sus scrofa 15377 R-SSC-6809720 https://reactome.org/PathwayBrowser/#/R-SSC-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Sus scrofa 15377 R-SSC-6809777 https://reactome.org/PathwayBrowser/#/R-SSC-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Sus scrofa 15377 R-SSC-6809778 https://reactome.org/PathwayBrowser/#/R-SSC-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Sus scrofa 15377 R-SSC-6810076 https://reactome.org/PathwayBrowser/#/R-SSC-6810076 DDO oxidizes D-Asp to OA IEA Sus scrofa 15377 R-SSC-6810410 https://reactome.org/PathwayBrowser/#/R-SSC-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Sus scrofa 15377 R-SSC-6810464 https://reactome.org/PathwayBrowser/#/R-SSC-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Sus scrofa 15377 R-SSC-6810472 https://reactome.org/PathwayBrowser/#/R-SSC-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Sus scrofa 15377 R-SSC-6810474 https://reactome.org/PathwayBrowser/#/R-SSC-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Sus scrofa 15377 R-SSC-6813720 https://reactome.org/PathwayBrowser/#/R-SSC-6813720 NCEH1 hydrolyzes cholesterol esters IEA Sus scrofa 15377 R-SSC-6813740 https://reactome.org/PathwayBrowser/#/R-SSC-6813740 GDE1 hydrolyzes GroPIns IEA Sus scrofa 15377 R-SSC-6813749 https://reactome.org/PathwayBrowser/#/R-SSC-6813749 ALDH1A1 oxidises GA to DGA IEA Sus scrofa 15377 R-SSC-6814254 https://reactome.org/PathwayBrowser/#/R-SSC-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Sus scrofa 15377 R-SSC-6814797 https://reactome.org/PathwayBrowser/#/R-SSC-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Sus scrofa 15377 R-SSC-69199 https://reactome.org/PathwayBrowser/#/R-SSC-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Sus scrofa 15377 R-SSC-70262 https://reactome.org/PathwayBrowser/#/R-SSC-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Sus scrofa 15377 R-SSC-70479 https://reactome.org/PathwayBrowser/#/R-SSC-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Sus scrofa 15377 R-SSC-70494 https://reactome.org/PathwayBrowser/#/R-SSC-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Sus scrofa 15377 R-SSC-70569 https://reactome.org/PathwayBrowser/#/R-SSC-70569 arginine + H2O => ornithine + urea [ARG1] IEA Sus scrofa 15377 R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Sus scrofa 15377 R-SSC-70599 https://reactome.org/PathwayBrowser/#/R-SSC-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Sus scrofa 15377 R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Sus scrofa 15377 R-SSC-70609 https://reactome.org/PathwayBrowser/#/R-SSC-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Sus scrofa 15377 R-SSC-70679 https://reactome.org/PathwayBrowser/#/R-SSC-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Sus scrofa 15377 R-SSC-70785 https://reactome.org/PathwayBrowser/#/R-SSC-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Sus scrofa 15377 R-SSC-70870 https://reactome.org/PathwayBrowser/#/R-SSC-70870 ECHS1 hydrates methacrylyl-CoA IEA Sus scrofa 15377 R-SSC-70881 https://reactome.org/PathwayBrowser/#/R-SSC-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Sus scrofa 15377 R-SSC-70903 https://reactome.org/PathwayBrowser/#/R-SSC-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Sus scrofa 15377 R-SSC-70906 https://reactome.org/PathwayBrowser/#/R-SSC-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Sus scrofa 15377 R-SSC-70938 https://reactome.org/PathwayBrowser/#/R-SSC-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Sus scrofa 15377 R-SSC-70940 https://reactome.org/PathwayBrowser/#/R-SSC-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Sus scrofa 15377 R-SSC-70941 https://reactome.org/PathwayBrowser/#/R-SSC-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Sus scrofa 15377 R-SSC-70975 https://reactome.org/PathwayBrowser/#/R-SSC-70975 CS acetylates OA to citrate IEA Sus scrofa 15377 R-SSC-70982 https://reactome.org/PathwayBrowser/#/R-SSC-70982 FH tetramer hydrates fumarate to L-malate IEA Sus scrofa 15377 R-SSC-71146 https://reactome.org/PathwayBrowser/#/R-SSC-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Sus scrofa 15377 R-SSC-71181 https://reactome.org/PathwayBrowser/#/R-SSC-71181 FAH cleaves 4FAA IEA Sus scrofa 15377 R-SSC-71200 https://reactome.org/PathwayBrowser/#/R-SSC-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Sus scrofa 15377 R-SSC-71217 https://reactome.org/PathwayBrowser/#/R-SSC-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Sus scrofa 15377 R-SSC-71260 https://reactome.org/PathwayBrowser/#/R-SSC-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Sus scrofa 15377 R-SSC-71296 https://reactome.org/PathwayBrowser/#/R-SSC-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Sus scrofa 15377 R-SSC-71660 https://reactome.org/PathwayBrowser/#/R-SSC-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Sus scrofa 15377 R-SSC-71676 https://reactome.org/PathwayBrowser/#/R-SSC-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Sus scrofa 15377 R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 15377 R-SSC-71723 https://reactome.org/PathwayBrowser/#/R-SSC-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Sus scrofa 15377 R-SSC-71732 https://reactome.org/PathwayBrowser/#/R-SSC-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Sus scrofa 15377 R-SSC-71825 https://reactome.org/PathwayBrowser/#/R-SSC-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Sus scrofa 15377 R-SSC-73571 https://reactome.org/PathwayBrowser/#/R-SSC-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Sus scrofa 15377 R-SSC-73577 https://reactome.org/PathwayBrowser/#/R-SSC-73577 CAD hexamer transforms L-Gln to CAP IEA Sus scrofa 15377 R-SSC-73589 https://reactome.org/PathwayBrowser/#/R-SSC-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Sus scrofa 15377 R-SSC-73591 https://reactome.org/PathwayBrowser/#/R-SSC-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Sus scrofa 15377 R-SSC-73596 https://reactome.org/PathwayBrowser/#/R-SSC-73596 dCMP + H2O => dUMP + NH4+ IEA Sus scrofa 15377 R-SSC-73608 https://reactome.org/PathwayBrowser/#/R-SSC-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Sus scrofa 15377 R-SSC-73618 https://reactome.org/PathwayBrowser/#/R-SSC-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Sus scrofa 15377 R-SSC-73620 https://reactome.org/PathwayBrowser/#/R-SSC-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Sus scrofa 15377 R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa 15377 R-SSC-73666 https://reactome.org/PathwayBrowser/#/R-SSC-73666 dUTP + H2O => dUMP + pyrophosphate IEA Sus scrofa 15377 R-SSC-73792 https://reactome.org/PathwayBrowser/#/R-SSC-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Sus scrofa 15377 R-SSC-73794 https://reactome.org/PathwayBrowser/#/R-SSC-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Sus scrofa 15377 R-SSC-73797 https://reactome.org/PathwayBrowser/#/R-SSC-73797 FAICAR => IMP + H2O IEA Sus scrofa 15377 R-SSC-73815 https://reactome.org/PathwayBrowser/#/R-SSC-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Sus scrofa 15377 R-SSC-74059 https://reactome.org/PathwayBrowser/#/R-SSC-74059 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 15377 R-SSC-74241 https://reactome.org/PathwayBrowser/#/R-SSC-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Sus scrofa 15377 R-SSC-74247 https://reactome.org/PathwayBrowser/#/R-SSC-74247 XDH oxidizes hypoxanthine to form xanthine IEA Sus scrofa 15377 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 15377 R-SSC-74255 https://reactome.org/PathwayBrowser/#/R-SSC-74255 Guanine + H2O => Xanthine + NH4+ IEA Sus scrofa 15377 R-SSC-74258 https://reactome.org/PathwayBrowser/#/R-SSC-74258 XDH oxidizes xanthine to form urate IEA Sus scrofa 15377 R-SSC-74733 https://reactome.org/PathwayBrowser/#/R-SSC-74733 Insulin receptor de-phosphorylation IEA Sus scrofa 15377 R-SSC-74948 https://reactome.org/PathwayBrowser/#/R-SSC-74948 PP2A dephosphorylates p-RHO to RHO IEA Sus scrofa 15377 R-SSC-75872 https://reactome.org/PathwayBrowser/#/R-SSC-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Sus scrofa 15377 R-SSC-75899 https://reactome.org/PathwayBrowser/#/R-SSC-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Sus scrofa 15377 R-SSC-76031 https://reactome.org/PathwayBrowser/#/R-SSC-76031 2 H2O2 => O2 + 2 H2O IEA Sus scrofa 15377 R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa 15377 R-SSC-76373 https://reactome.org/PathwayBrowser/#/R-SSC-76373 N-hydroxylation of 4-aminobiphenyl IEA Sus scrofa 15377 R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 15377 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa 15377 R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa 15377 R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 15377 R-SSC-76453 https://reactome.org/PathwayBrowser/#/R-SSC-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Sus scrofa 15377 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 15377 R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 15377 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 15377 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 15377 R-SSC-76590 https://reactome.org/PathwayBrowser/#/R-SSC-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Sus scrofa 15377 R-SSC-77256 https://reactome.org/PathwayBrowser/#/R-SSC-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Sus scrofa 15377 R-SSC-77277 https://reactome.org/PathwayBrowser/#/R-SSC-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Sus scrofa 15377 R-SSC-77301 https://reactome.org/PathwayBrowser/#/R-SSC-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Sus scrofa 15377 R-SSC-77314 https://reactome.org/PathwayBrowser/#/R-SSC-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Sus scrofa 15377 R-SSC-77325 https://reactome.org/PathwayBrowser/#/R-SSC-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Sus scrofa 15377 R-SSC-77333 https://reactome.org/PathwayBrowser/#/R-SSC-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Sus scrofa 15377 R-SSC-77344 https://reactome.org/PathwayBrowser/#/R-SSC-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Sus scrofa 15377 R-SSC-77614 https://reactome.org/PathwayBrowser/#/R-SSC-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Sus scrofa 15377 R-SSC-77615 https://reactome.org/PathwayBrowser/#/R-SSC-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Sus scrofa 15377 R-SSC-83677 https://reactome.org/PathwayBrowser/#/R-SSC-83677 C4 deamination of cytidine IEA Sus scrofa 15377 R-SSC-870437 https://reactome.org/PathwayBrowser/#/R-SSC-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Sus scrofa 15377 R-SSC-8847579 https://reactome.org/PathwayBrowser/#/R-SSC-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15377 R-SSC-8848053 https://reactome.org/PathwayBrowser/#/R-SSC-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Sus scrofa 15377 R-SSC-8848215 https://reactome.org/PathwayBrowser/#/R-SSC-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Sus scrofa 15377 R-SSC-8848338 https://reactome.org/PathwayBrowser/#/R-SSC-8848338 PNPLA4 hydrolyzes TAG IEA Sus scrofa 15377 R-SSC-8848355 https://reactome.org/PathwayBrowser/#/R-SSC-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Sus scrofa 15377 R-SSC-8848484 https://reactome.org/PathwayBrowser/#/R-SSC-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Sus scrofa 15377 R-SSC-8849435 https://reactome.org/PathwayBrowser/#/R-SSC-8849435 PTPN1 dephosphorylates PTK6 IEA Sus scrofa 15377 R-SSC-8849857 https://reactome.org/PathwayBrowser/#/R-SSC-8849857 KLK5 cleaves and activates CELA2 IEA Sus scrofa 15377 R-SSC-8849969 https://reactome.org/PathwayBrowser/#/R-SSC-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Sus scrofa 15377 R-SSC-8850594 https://reactome.org/PathwayBrowser/#/R-SSC-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Sus scrofa 15377 R-SSC-8850831 https://reactome.org/PathwayBrowser/#/R-SSC-8850831 KLK5 cleaves and activates KLK8 IEA Sus scrofa 15377 R-SSC-8850846 https://reactome.org/PathwayBrowser/#/R-SSC-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-SSC-8850854 https://reactome.org/PathwayBrowser/#/R-SSC-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-SSC-8851110 https://reactome.org/PathwayBrowser/#/R-SSC-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-SSC-8851129 https://reactome.org/PathwayBrowser/#/R-SSC-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-SSC-8852200 https://reactome.org/PathwayBrowser/#/R-SSC-8852200 Inactivation of LCK by PTPN22 IEA Sus scrofa 15377 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 15377 R-SSC-8853686 https://reactome.org/PathwayBrowser/#/R-SSC-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Sus scrofa 15377 R-SSC-8854173 https://reactome.org/PathwayBrowser/#/R-SSC-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Sus scrofa 15377 R-SSC-8854255 https://reactome.org/PathwayBrowser/#/R-SSC-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 15377 R-SSC-8854329 https://reactome.org/PathwayBrowser/#/R-SSC-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 15377 R-SSC-8854604 https://reactome.org/PathwayBrowser/#/R-SSC-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Sus scrofa 15377 R-SSC-8854612 https://reactome.org/PathwayBrowser/#/R-SSC-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Sus scrofa 15377 R-SSC-8855381 https://reactome.org/PathwayBrowser/#/R-SSC-8855381 PTPN22 dephosphorylates ZAP70 IEA Sus scrofa 15377 R-SSC-8855490 https://reactome.org/PathwayBrowser/#/R-SSC-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Sus scrofa 15377 R-SSC-8855825 https://reactome.org/PathwayBrowser/#/R-SSC-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Sus scrofa 15377 R-SSC-8856951 https://reactome.org/PathwayBrowser/#/R-SSC-8856951 PP2A demethylation by PPME1 IEA Sus scrofa 15377 R-SSC-8862184 https://reactome.org/PathwayBrowser/#/R-SSC-8862184 USP48 cleaves polyubiquitin IEA Sus scrofa 15377 R-SSC-8862320 https://reactome.org/PathwayBrowser/#/R-SSC-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Sus scrofa 15377 R-SSC-8863804 https://reactome.org/PathwayBrowser/#/R-SSC-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Sus scrofa 15377 R-SSC-8864029 https://reactome.org/PathwayBrowser/#/R-SSC-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Sus scrofa 15377 R-SSC-8864036 https://reactome.org/PathwayBrowser/#/R-SSC-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Sus scrofa 15377 R-SSC-8864125 https://reactome.org/PathwayBrowser/#/R-SSC-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Sus scrofa 15377 R-SSC-8865667 https://reactome.org/PathwayBrowser/#/R-SSC-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Sus scrofa 15377 R-SSC-8866405 https://reactome.org/PathwayBrowser/#/R-SSC-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 15377 R-SSC-8866542 https://reactome.org/PathwayBrowser/#/R-SSC-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Sus scrofa 15377 R-SSC-8866601 https://reactome.org/PathwayBrowser/#/R-SSC-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Sus scrofa 15377 R-SSC-8867047 https://reactome.org/PathwayBrowser/#/R-SSC-8867047 PTPN3 dephosphorylates EPS15 IEA Sus scrofa 15377 R-SSC-8867344 https://reactome.org/PathwayBrowser/#/R-SSC-8867344 OMA1 hydrolyses OPA1 IEA Sus scrofa 15377 R-SSC-8867658 https://reactome.org/PathwayBrowser/#/R-SSC-8867658 PTPN3 dephosphorylates MAPK12 IEA Sus scrofa 15377 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 15377 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 15377 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 15377 R-SSC-8869206 https://reactome.org/PathwayBrowser/#/R-SSC-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Sus scrofa 15377 R-SSC-8869425 https://reactome.org/PathwayBrowser/#/R-SSC-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Sus scrofa 15377 R-SSC-8869456 https://reactome.org/PathwayBrowser/#/R-SSC-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Sus scrofa 15377 R-SSC-8869506 https://reactome.org/PathwayBrowser/#/R-SSC-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Sus scrofa 15377 R-SSC-8870346 https://reactome.org/PathwayBrowser/#/R-SSC-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Sus scrofa 15377 R-SSC-8874435 https://reactome.org/PathwayBrowser/#/R-SSC-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Sus scrofa 15377 R-SSC-8875443 https://reactome.org/PathwayBrowser/#/R-SSC-8875443 USP8 deubiquitinates LRIG1 IEA Sus scrofa 15377 R-SSC-8878581 https://reactome.org/PathwayBrowser/#/R-SSC-8878581 TYRP1 oxidises DHICA to IQCA IEA Sus scrofa 15377 R-SSC-8878654 https://reactome.org/PathwayBrowser/#/R-SSC-8878654 ACP6 hydrolyses MYS-LPA IEA Sus scrofa 15377 R-SSC-8878787 https://reactome.org/PathwayBrowser/#/R-SSC-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Sus scrofa 15377 R-SSC-888548 https://reactome.org/PathwayBrowser/#/R-SSC-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Sus scrofa 15377 R-SSC-8932633 https://reactome.org/PathwayBrowser/#/R-SSC-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Sus scrofa 15377 R-SSC-8933328 https://reactome.org/PathwayBrowser/#/R-SSC-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Sus scrofa 15377 R-SSC-8933635 https://reactome.org/PathwayBrowser/#/R-SSC-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Sus scrofa 15377 R-SSC-8936442 https://reactome.org/PathwayBrowser/#/R-SSC-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Sus scrofa 15377 R-SSC-8937442 https://reactome.org/PathwayBrowser/#/R-SSC-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Sus scrofa 15377 R-SSC-8937767 https://reactome.org/PathwayBrowser/#/R-SSC-8937767 PTPN11 dephosphorylates RUNX1 IEA Sus scrofa 15377 R-SSC-8938076 https://reactome.org/PathwayBrowser/#/R-SSC-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Sus scrofa 15377 R-SSC-8940070 https://reactome.org/PathwayBrowser/#/R-SSC-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Sus scrofa 15377 R-SSC-8940074 https://reactome.org/PathwayBrowser/#/R-SSC-8940074 NT5E:Zn2+ hydrolyses NMN IEA Sus scrofa 15377 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa 15377 R-SSC-8943279 https://reactome.org/PathwayBrowser/#/R-SSC-8943279 GGT dimers hydrolyse GSH IEA Sus scrofa 15377 R-SSC-8952137 https://reactome.org/PathwayBrowser/#/R-SSC-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Sus scrofa 15377 R-SSC-8952251 https://reactome.org/PathwayBrowser/#/R-SSC-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Sus scrofa 15377 R-SSC-8952903 https://reactome.org/PathwayBrowser/#/R-SSC-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Sus scrofa 15377 R-SSC-8953339 https://reactome.org/PathwayBrowser/#/R-SSC-8953339 DNPH1 hydrolyses dGMP IEA Sus scrofa 15377 R-SSC-8953499 https://reactome.org/PathwayBrowser/#/R-SSC-8953499 IMPAD1 hydrolyses PAP to AMP IEA Sus scrofa 15377 R-SSC-8954398 https://reactome.org/PathwayBrowser/#/R-SSC-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Sus scrofa 15377 R-SSC-8955817 https://reactome.org/PathwayBrowser/#/R-SSC-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Sus scrofa 15377 R-SSC-8957389 https://reactome.org/PathwayBrowser/#/R-SSC-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Sus scrofa 15377 R-SSC-8959510 https://reactome.org/PathwayBrowser/#/R-SSC-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Sus scrofa 15377 R-SSC-8980228 https://reactome.org/PathwayBrowser/#/R-SSC-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Sus scrofa 15377 R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa 15377 R-SSC-8985594 https://reactome.org/PathwayBrowser/#/R-SSC-8985594 MYO9B inactivates RHOA IEA Sus scrofa 15377 R-SSC-9008822 https://reactome.org/PathwayBrowser/#/R-SSC-9008822 PPM1D dephosphorylates RUNX2 IEA Sus scrofa 15377 R-SSC-9009950 https://reactome.org/PathwayBrowser/#/R-SSC-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Sus scrofa 15377 R-SSC-9013022 https://reactome.org/PathwayBrowser/#/R-SSC-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Sus scrofa 15377 R-SSC-9013111 https://reactome.org/PathwayBrowser/#/R-SSC-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Sus scrofa 15377 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa 15377 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa 15377 R-SSC-9013437 https://reactome.org/PathwayBrowser/#/R-SSC-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Sus scrofa 15377 R-SSC-9014295 https://reactome.org/PathwayBrowser/#/R-SSC-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Sus scrofa 15377 R-SSC-9014434 https://reactome.org/PathwayBrowser/#/R-SSC-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Sus scrofa 15377 R-SSC-9014627 https://reactome.org/PathwayBrowser/#/R-SSC-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Sus scrofa 15377 R-SSC-9014741 https://reactome.org/PathwayBrowser/#/R-SSC-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Sus scrofa 15377 R-SSC-9017488 https://reactome.org/PathwayBrowser/#/R-SSC-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Sus scrofa 15377 R-SSC-9018745 https://reactome.org/PathwayBrowser/#/R-SSC-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Sus scrofa 15377 R-SSC-9018806 https://reactome.org/PathwayBrowser/#/R-SSC-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Sus scrofa 15377 R-SSC-9018814 https://reactome.org/PathwayBrowser/#/R-SSC-9018814 RHOT1 hydrolyzes GTP IEA Sus scrofa 15377 R-SSC-9018826 https://reactome.org/PathwayBrowser/#/R-SSC-9018826 RHOT2 hydrolyzes GTP IEA Sus scrofa 15377 R-SSC-9018862 https://reactome.org/PathwayBrowser/#/R-SSC-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Sus scrofa 15377 R-SSC-9018868 https://reactome.org/PathwayBrowser/#/R-SSC-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Sus scrofa 15377 R-SSC-9018877 https://reactome.org/PathwayBrowser/#/R-SSC-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Sus scrofa 15377 R-SSC-9018895 https://reactome.org/PathwayBrowser/#/R-SSC-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Sus scrofa 15377 R-SSC-9020252 https://reactome.org/PathwayBrowser/#/R-SSC-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Sus scrofa 15377 R-SSC-9020253 https://reactome.org/PathwayBrowser/#/R-SSC-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Sus scrofa 15377 R-SSC-9020257 https://reactome.org/PathwayBrowser/#/R-SSC-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Sus scrofa 15377 R-SSC-9020258 https://reactome.org/PathwayBrowser/#/R-SSC-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Sus scrofa 15377 R-SSC-9020270 https://reactome.org/PathwayBrowser/#/R-SSC-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Sus scrofa 15377 R-SSC-9020271 https://reactome.org/PathwayBrowser/#/R-SSC-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Sus scrofa 15377 R-SSC-9020273 https://reactome.org/PathwayBrowser/#/R-SSC-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Sus scrofa 15377 R-SSC-9024890 https://reactome.org/PathwayBrowser/#/R-SSC-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Sus scrofa 15377 R-SSC-9027043 https://reactome.org/PathwayBrowser/#/R-SSC-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Sus scrofa 15377 R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 15377 R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 15377 R-SSC-9033491 https://reactome.org/PathwayBrowser/#/R-SSC-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Sus scrofa 15377 R-SSC-9033520 https://reactome.org/PathwayBrowser/#/R-SSC-9033520 TYSND1 cleaves TYSND1 IEA Sus scrofa 15377 R-SSC-9034539 https://reactome.org/PathwayBrowser/#/R-SSC-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Sus scrofa 15377 R-SSC-9036727 https://reactome.org/PathwayBrowser/#/R-SSC-9036727 GAA hydrolyzes lysosomal glycogen IEA Sus scrofa 15377 R-SSC-9037761 https://reactome.org/PathwayBrowser/#/R-SSC-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Sus scrofa 15377 R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa 15377 R-SSC-917891 https://reactome.org/PathwayBrowser/#/R-SSC-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Sus scrofa 15377 R-SSC-917933 https://reactome.org/PathwayBrowser/#/R-SSC-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Sus scrofa 15377 R-SSC-917979 https://reactome.org/PathwayBrowser/#/R-SSC-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Sus scrofa 15377 R-SSC-936802 https://reactome.org/PathwayBrowser/#/R-SSC-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Sus scrofa 15377 R-SSC-936883 https://reactome.org/PathwayBrowser/#/R-SSC-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Sus scrofa 15377 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 15377 R-SSC-937311 https://reactome.org/PathwayBrowser/#/R-SSC-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Sus scrofa 15377 R-SSC-939763 https://reactome.org/PathwayBrowser/#/R-SSC-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Sus scrofa 15377 R-SSC-947531 https://reactome.org/PathwayBrowser/#/R-SSC-947531 Molybdenum ion transfer onto molybdopterin IEA Sus scrofa 15377 R-SSC-947535 https://reactome.org/PathwayBrowser/#/R-SSC-947535 Cyclisation of GTP to precursor Z IEA Sus scrofa 15377 R-SSC-947591 https://reactome.org/PathwayBrowser/#/R-SSC-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Sus scrofa 15377 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 15377 R-SSC-9620103 https://reactome.org/PathwayBrowser/#/R-SSC-9620103 ALDH2 transforms GTN to NO IEA Sus scrofa 15377 R-SSC-9624893 https://reactome.org/PathwayBrowser/#/R-SSC-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Sus scrofa 15377 R-SSC-9629675 https://reactome.org/PathwayBrowser/#/R-SSC-9629675 PDE3A hydrolyses cAMP to AMP IEA Sus scrofa 15377 R-SSC-9638075 https://reactome.org/PathwayBrowser/#/R-SSC-9638075 HEXB cleaves the terminal GalNAc from DS IEA Sus scrofa 15377 R-SSC-9638076 https://reactome.org/PathwayBrowser/#/R-SSC-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Sus scrofa 15377 R-SSC-9638078 https://reactome.org/PathwayBrowser/#/R-SSC-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Sus scrofa 15377 R-SSC-9638120 https://reactome.org/PathwayBrowser/#/R-SSC-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 15377 R-SSC-9644869 https://reactome.org/PathwayBrowser/#/R-SSC-9644869 p-S54-PDE4B hydrolyses cAMP IEA Sus scrofa 15377 R-SSC-9647994 https://reactome.org/PathwayBrowser/#/R-SSC-9647994 RAS proteins are depalmitoylated IEA Sus scrofa 15377 R-SSC-965067 https://reactome.org/PathwayBrowser/#/R-SSC-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Sus scrofa 15377 R-SSC-965079 https://reactome.org/PathwayBrowser/#/R-SSC-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Sus scrofa 15377 R-SSC-9653514 https://reactome.org/PathwayBrowser/#/R-SSC-9653514 USP17L2 deubiquitinates RCE1 IEA Sus scrofa 15377 R-SSC-9656891 https://reactome.org/PathwayBrowser/#/R-SSC-9656891 OPN1SW binds 11cRAL IEA Sus scrofa 15377 R-SSC-9656893 https://reactome.org/PathwayBrowser/#/R-SSC-9656893 OPN1MW binds 11cRAL IEA Sus scrofa 15377 R-SSC-9658445 https://reactome.org/PathwayBrowser/#/R-SSC-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Sus scrofa 15377 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 15377 R-SSC-9661417 https://reactome.org/PathwayBrowser/#/R-SSC-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 15377 R-SSC-9667952 https://reactome.org/PathwayBrowser/#/R-SSC-9667952 ANKLE2 is deacetylated by SIRT2 IEA Sus scrofa 15377 R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa 15377 R-SSC-9673053 https://reactome.org/PathwayBrowser/#/R-SSC-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Sus scrofa 15377 R-SSC-9673054 https://reactome.org/PathwayBrowser/#/R-SSC-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Sus scrofa 15377 R-SSC-9674127 https://reactome.org/PathwayBrowser/#/R-SSC-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Sus scrofa 15377 R-SSC-9686524 https://reactome.org/PathwayBrowser/#/R-SSC-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Sus scrofa 15377 R-SSC-9693282 https://reactome.org/PathwayBrowser/#/R-SSC-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Sus scrofa 15377 R-SSC-9700200 https://reactome.org/PathwayBrowser/#/R-SSC-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Sus scrofa 15377 R-SSC-9701507 https://reactome.org/PathwayBrowser/#/R-SSC-9701507 PTPN6 dephosphorylates JAK3 IEA Sus scrofa 15377 R-SSC-9701565 https://reactome.org/PathwayBrowser/#/R-SSC-9701565 HDACs deacetylate p-STAT3 dimers IEA Sus scrofa 15377 R-SSC-9705507 https://reactome.org/PathwayBrowser/#/R-SSC-9705507 PDE3B hydrolyses cAMP to AMP IEA Sus scrofa 15377 R-SSC-9708261 https://reactome.org/PathwayBrowser/#/R-SSC-9708261 PDE4A hydrolyses cAMP to AMP IEA Sus scrofa 15377 R-SSC-9709360 https://reactome.org/PathwayBrowser/#/R-SSC-9709360 H2O2 reduces MetHb IEA Sus scrofa 15377 R-SSC-9727198 https://reactome.org/PathwayBrowser/#/R-SSC-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Sus scrofa 15377 R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 15377 R-SSC-9727349 https://reactome.org/PathwayBrowser/#/R-SSC-9727349 XDH dehydrogenates xanthine to form urate IEA Sus scrofa 15377 R-SSC-9727567 https://reactome.org/PathwayBrowser/#/R-SSC-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Sus scrofa 15377 R-SSC-9731228 https://reactome.org/PathwayBrowser/#/R-SSC-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Sus scrofa 15377 R-SSC-9731590 https://reactome.org/PathwayBrowser/#/R-SSC-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Sus scrofa 15377 R-SSC-9731613 https://reactome.org/PathwayBrowser/#/R-SSC-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Sus scrofa 15377 R-SSC-9731632 https://reactome.org/PathwayBrowser/#/R-SSC-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Sus scrofa 15377 R-SSC-9731661 https://reactome.org/PathwayBrowser/#/R-SSC-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Sus scrofa 15377 R-SSC-9748945 https://reactome.org/PathwayBrowser/#/R-SSC-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Sus scrofa 15377 R-SSC-9748957 https://reactome.org/PathwayBrowser/#/R-SSC-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Sus scrofa 15377 R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 15377 R-SSC-9749792 https://reactome.org/PathwayBrowser/#/R-SSC-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Sus scrofa 15377 R-SSC-9749986 https://reactome.org/PathwayBrowser/#/R-SSC-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Sus scrofa 15377 R-SSC-9750016 https://reactome.org/PathwayBrowser/#/R-SSC-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Sus scrofa 15377 R-SSC-9750546 https://reactome.org/PathwayBrowser/#/R-SSC-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 15377 R-SSC-9750555 https://reactome.org/PathwayBrowser/#/R-SSC-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Sus scrofa 15377 R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 15377 R-SSC-9750656 https://reactome.org/PathwayBrowser/#/R-SSC-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Sus scrofa 15377 R-SSC-9750942 https://reactome.org/PathwayBrowser/#/R-SSC-9750942 USP14 deubiquitinates NLRC5 IEA Sus scrofa 15377 R-SSC-9753278 https://reactome.org/PathwayBrowser/#/R-SSC-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 15377 R-SSC-9753280 https://reactome.org/PathwayBrowser/#/R-SSC-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Sus scrofa 15377 R-SSC-9753283 https://reactome.org/PathwayBrowser/#/R-SSC-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 15377 R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 15377 R-SSC-9753285 https://reactome.org/PathwayBrowser/#/R-SSC-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Sus scrofa 15377 R-SSC-9753632 https://reactome.org/PathwayBrowser/#/R-SSC-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Sus scrofa 15377 R-SSC-9753634 https://reactome.org/PathwayBrowser/#/R-SSC-9753634 GGT dimers hydrolyse APAP-SG IEA Sus scrofa 15377 R-SSC-9753944 https://reactome.org/PathwayBrowser/#/R-SSC-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Sus scrofa 15377 R-SSC-9754964 https://reactome.org/PathwayBrowser/#/R-SSC-9754964 ADA deamidates RBV IEA Sus scrofa 15377 R-SSC-9755030 https://reactome.org/PathwayBrowser/#/R-SSC-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Sus scrofa 15377 R-SSC-9755078 https://reactome.org/PathwayBrowser/#/R-SSC-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Sus scrofa 15377 R-SSC-975593 https://reactome.org/PathwayBrowser/#/R-SSC-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Sus scrofa 15377 R-SSC-975594 https://reactome.org/PathwayBrowser/#/R-SSC-975594 PLB1 hydrolyses RPALM to atROL IEA Sus scrofa 15377 R-SSC-9756138 https://reactome.org/PathwayBrowser/#/R-SSC-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Sus scrofa 15377 R-SSC-9756162 https://reactome.org/PathwayBrowser/#/R-SSC-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Sus scrofa 15377 R-SSC-9756169 https://reactome.org/PathwayBrowser/#/R-SSC-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Sus scrofa 15377 R-SSC-9756177 https://reactome.org/PathwayBrowser/#/R-SSC-9756177 PON1,3 hydrolyse ATVL to ATV IEA Sus scrofa 15377 R-SSC-9756180 https://reactome.org/PathwayBrowser/#/R-SSC-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Sus scrofa 15377 R-SSC-9758674 https://reactome.org/PathwayBrowser/#/R-SSC-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Sus scrofa 15377 R-SSC-9759206 https://reactome.org/PathwayBrowser/#/R-SSC-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Sus scrofa 15377 R-SSC-9759454 https://reactome.org/PathwayBrowser/#/R-SSC-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Sus scrofa 15377 R-SSC-9759461 https://reactome.org/PathwayBrowser/#/R-SSC-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Sus scrofa 15377 R-SSC-977324 https://reactome.org/PathwayBrowser/#/R-SSC-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Sus scrofa 15377 R-SSC-9794120 https://reactome.org/PathwayBrowser/#/R-SSC-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Sus scrofa 15377 R-SSC-9794572 https://reactome.org/PathwayBrowser/#/R-SSC-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Sus scrofa 15377 R-SSC-983144 https://reactome.org/PathwayBrowser/#/R-SSC-983144 Transport of Antigen peptide in to ER IEA Sus scrofa 15377 R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa 15377 R-SSC-9837419 https://reactome.org/PathwayBrowser/#/R-SSC-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Sus scrofa 15377 R-SSC-9838004 https://reactome.org/PathwayBrowser/#/R-SSC-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Sus scrofa 15377 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa 15377 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa 15377 R-SSC-9839059 https://reactome.org/PathwayBrowser/#/R-SSC-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Sus scrofa 15377 R-SSC-9839072 https://reactome.org/PathwayBrowser/#/R-SSC-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Sus scrofa 15377 R-SSC-9839105 https://reactome.org/PathwayBrowser/#/R-SSC-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Sus scrofa 15377 R-SSC-9839110 https://reactome.org/PathwayBrowser/#/R-SSC-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Sus scrofa 15377 R-SSC-9839113 https://reactome.org/PathwayBrowser/#/R-SSC-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Sus scrofa 15377 R-SSC-9840408 https://reactome.org/PathwayBrowser/#/R-SSC-9840408 OMA1 cleaves DELE1 IEA Sus scrofa 15377 R-SSC-9840795 https://reactome.org/PathwayBrowser/#/R-SSC-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Sus scrofa 15377 R-SSC-9840833 https://reactome.org/PathwayBrowser/#/R-SSC-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Sus scrofa 15377 R-SSC-9840884 https://reactome.org/PathwayBrowser/#/R-SSC-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Sus scrofa 15377 R-SSC-9840949 https://reactome.org/PathwayBrowser/#/R-SSC-9840949 ARSA removes sulfate from SM3 IEA Sus scrofa 15377 R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 15377 R-SSC-9843721 https://reactome.org/PathwayBrowser/#/R-SSC-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Sus scrofa 15377 R-SSC-9853385 https://reactome.org/PathwayBrowser/#/R-SSC-9853385 PPP1CC dephosphorylates PLK1 IEA Sus scrofa 15377 R-SSC-9861626 https://reactome.org/PathwayBrowser/#/R-SSC-9861626 SIRT4 cleaves lipoyl from DLAT IEA Sus scrofa 15377 R-SSC-9861725 https://reactome.org/PathwayBrowser/#/R-SSC-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Sus scrofa 15377 R-SSC-997309 https://reactome.org/PathwayBrowser/#/R-SSC-997309 Dephosphorylation of STAT1 by SHP2 IEA Sus scrofa 15377 R-SSC-997311 https://reactome.org/PathwayBrowser/#/R-SSC-997311 Dephosphorylation of TYK2 by PTP1B IEA Sus scrofa 15377 R-SSC-997314 https://reactome.org/PathwayBrowser/#/R-SSC-997314 Dephosphorylation of JAK1 by SHP1 IEA Sus scrofa 15377 R-SSC-997326 https://reactome.org/PathwayBrowser/#/R-SSC-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Sus scrofa 15377 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 15377 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 15377 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 15377 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 15377 R-XTR-109415 https://reactome.org/PathwayBrowser/#/R-XTR-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Xenopus tropicalis 15377 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 15377 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 15377 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 15377 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 15377 R-XTR-111742 https://reactome.org/PathwayBrowser/#/R-XTR-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 15377 R-XTR-111879 https://reactome.org/PathwayBrowser/#/R-XTR-111879 PIP2 hydrolysis IEA Xenopus tropicalis 15377 R-XTR-111883 https://reactome.org/PathwayBrowser/#/R-XTR-111883 Hydrolysis of phosphatidylcholine IEA Xenopus tropicalis 15377 R-XTR-111955 https://reactome.org/PathwayBrowser/#/R-XTR-111955 cAMP hydrolysis by Cam-PDE 1 IEA Xenopus tropicalis 15377 R-XTR-111962 https://reactome.org/PathwayBrowser/#/R-XTR-111962 PDE4A,C,D hydrolyse cAMP IEA Xenopus tropicalis 15377 R-XTR-112037 https://reactome.org/PathwayBrowser/#/R-XTR-112037 Inactivation of PLC beta IEA Xenopus tropicalis 15377 R-XTR-1183128 https://reactome.org/PathwayBrowser/#/R-XTR-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Xenopus tropicalis 15377 R-XTR-1237047 https://reactome.org/PathwayBrowser/#/R-XTR-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Xenopus tropicalis 15377 R-XTR-1237059 https://reactome.org/PathwayBrowser/#/R-XTR-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Xenopus tropicalis 15377 R-XTR-1237129 https://reactome.org/PathwayBrowser/#/R-XTR-1237129 Acireductone is created IEA Xenopus tropicalis 15377 R-XTR-1247910 https://reactome.org/PathwayBrowser/#/R-XTR-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Xenopus tropicalis 15377 R-XTR-1247935 https://reactome.org/PathwayBrowser/#/R-XTR-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Xenopus tropicalis 15377 R-XTR-1363274 https://reactome.org/PathwayBrowser/#/R-XTR-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Xenopus tropicalis 15377 R-XTR-1363276 https://reactome.org/PathwayBrowser/#/R-XTR-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Xenopus tropicalis 15377 R-XTR-1369065 https://reactome.org/PathwayBrowser/#/R-XTR-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Xenopus tropicalis 15377 R-XTR-139906 https://reactome.org/PathwayBrowser/#/R-XTR-139906 Activation of BAD by calcineurin IEA Xenopus tropicalis 15377 R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 15377 R-XTR-140359 https://reactome.org/PathwayBrowser/#/R-XTR-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Xenopus tropicalis 15377 R-XTR-141200 https://reactome.org/PathwayBrowser/#/R-XTR-141200 MAOB:FAD oxidatively deaminates of PEA IEA Xenopus tropicalis 15377 R-XTR-141202 https://reactome.org/PathwayBrowser/#/R-XTR-141202 MAOB:FAD oxidatively deaminates TYR IEA Xenopus tropicalis 15377 R-XTR-141341 https://reactome.org/PathwayBrowser/#/R-XTR-141341 SMOX-3 oxidises SPN to SPM IEA Xenopus tropicalis 15377 R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 15377 R-XTR-1454916 https://reactome.org/PathwayBrowser/#/R-XTR-1454916 The ABCC family mediates organic anion transport IEA Xenopus tropicalis 15377 R-XTR-1454928 https://reactome.org/PathwayBrowser/#/R-XTR-1454928 ABCG4 may mediate cholesterol efflux IEA Xenopus tropicalis 15377 R-XTR-1467466 https://reactome.org/PathwayBrowser/#/R-XTR-1467466 ABCA4 mediates atRAL transport IEA Xenopus tropicalis 15377 R-XTR-1474146 https://reactome.org/PathwayBrowser/#/R-XTR-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Xenopus tropicalis 15377 R-XTR-1475017 https://reactome.org/PathwayBrowser/#/R-XTR-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Xenopus tropicalis 15377 R-XTR-1475022 https://reactome.org/PathwayBrowser/#/R-XTR-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Xenopus tropicalis 15377 R-XTR-1475025 https://reactome.org/PathwayBrowser/#/R-XTR-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Xenopus tropicalis 15377 R-XTR-1475026 https://reactome.org/PathwayBrowser/#/R-XTR-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Xenopus tropicalis 15377 R-XTR-1475028 https://reactome.org/PathwayBrowser/#/R-XTR-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Xenopus tropicalis 15377 R-XTR-1475032 https://reactome.org/PathwayBrowser/#/R-XTR-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Xenopus tropicalis 15377 R-XTR-1475435 https://reactome.org/PathwayBrowser/#/R-XTR-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Xenopus tropicalis 15377 R-XTR-1475436 https://reactome.org/PathwayBrowser/#/R-XTR-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Xenopus tropicalis 15377 R-XTR-1482543 https://reactome.org/PathwayBrowser/#/R-XTR-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Xenopus tropicalis 15377 R-XTR-1482604 https://reactome.org/PathwayBrowser/#/R-XTR-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Xenopus tropicalis 15377 R-XTR-1482612 https://reactome.org/PathwayBrowser/#/R-XTR-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 15377 R-XTR-1482656 https://reactome.org/PathwayBrowser/#/R-XTR-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Xenopus tropicalis 15377 R-XTR-1482679 https://reactome.org/PathwayBrowser/#/R-XTR-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Xenopus tropicalis 15377 R-XTR-1482685 https://reactome.org/PathwayBrowser/#/R-XTR-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 15377 R-XTR-1482745 https://reactome.org/PathwayBrowser/#/R-XTR-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Xenopus tropicalis 15377 R-XTR-1482759 https://reactome.org/PathwayBrowser/#/R-XTR-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Xenopus tropicalis 15377 R-XTR-1482771 https://reactome.org/PathwayBrowser/#/R-XTR-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Xenopus tropicalis 15377 R-XTR-1482776 https://reactome.org/PathwayBrowser/#/R-XTR-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Xenopus tropicalis 15377 R-XTR-1482777 https://reactome.org/PathwayBrowser/#/R-XTR-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Xenopus tropicalis 15377 R-XTR-1482811 https://reactome.org/PathwayBrowser/#/R-XTR-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Xenopus tropicalis 15377 R-XTR-1482816 https://reactome.org/PathwayBrowser/#/R-XTR-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Xenopus tropicalis 15377 R-XTR-1482825 https://reactome.org/PathwayBrowser/#/R-XTR-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Xenopus tropicalis 15377 R-XTR-1482828 https://reactome.org/PathwayBrowser/#/R-XTR-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Xenopus tropicalis 15377 R-XTR-1482847 https://reactome.org/PathwayBrowser/#/R-XTR-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Xenopus tropicalis 15377 R-XTR-1482856 https://reactome.org/PathwayBrowser/#/R-XTR-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Xenopus tropicalis 15377 R-XTR-1482862 https://reactome.org/PathwayBrowser/#/R-XTR-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Xenopus tropicalis 15377 R-XTR-1482868 https://reactome.org/PathwayBrowser/#/R-XTR-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Xenopus tropicalis 15377 R-XTR-1482884 https://reactome.org/PathwayBrowser/#/R-XTR-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Xenopus tropicalis 15377 R-XTR-1482887 https://reactome.org/PathwayBrowser/#/R-XTR-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Xenopus tropicalis 15377 R-XTR-1482897 https://reactome.org/PathwayBrowser/#/R-XTR-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Xenopus tropicalis 15377 R-XTR-1482900 https://reactome.org/PathwayBrowser/#/R-XTR-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Xenopus tropicalis 15377 R-XTR-1482907 https://reactome.org/PathwayBrowser/#/R-XTR-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Xenopus tropicalis 15377 R-XTR-1482920 https://reactome.org/PathwayBrowser/#/R-XTR-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Xenopus tropicalis 15377 R-XTR-1483096 https://reactome.org/PathwayBrowser/#/R-XTR-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Xenopus tropicalis 15377 R-XTR-1483159 https://reactome.org/PathwayBrowser/#/R-XTR-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Xenopus tropicalis 15377 R-XTR-1483182 https://reactome.org/PathwayBrowser/#/R-XTR-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Xenopus tropicalis 15377 R-XTR-1483203 https://reactome.org/PathwayBrowser/#/R-XTR-1483203 PA is dephosphorylated to DAG by LPIN IEA Xenopus tropicalis 15377 R-XTR-156526 https://reactome.org/PathwayBrowser/#/R-XTR-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 15377 R-XTR-159425 https://reactome.org/PathwayBrowser/#/R-XTR-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 15377 R-XTR-159752 https://reactome.org/PathwayBrowser/#/R-XTR-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Xenopus tropicalis 15377 R-XTR-159761 https://reactome.org/PathwayBrowser/#/R-XTR-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Xenopus tropicalis 15377 R-XTR-159795 https://reactome.org/PathwayBrowser/#/R-XTR-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Xenopus tropicalis 15377 R-XTR-159803 https://reactome.org/PathwayBrowser/#/R-XTR-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Xenopus tropicalis 15377 R-XTR-159819 https://reactome.org/PathwayBrowser/#/R-XTR-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Xenopus tropicalis 15377 R-XTR-159826 https://reactome.org/PathwayBrowser/#/R-XTR-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Xenopus tropicalis 15377 R-XTR-1602368 https://reactome.org/PathwayBrowser/#/R-XTR-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Xenopus tropicalis 15377 R-XTR-1602374 https://reactome.org/PathwayBrowser/#/R-XTR-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Xenopus tropicalis 15377 R-XTR-1602377 https://reactome.org/PathwayBrowser/#/R-XTR-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Xenopus tropicalis 15377 R-XTR-1602398 https://reactome.org/PathwayBrowser/#/R-XTR-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Xenopus tropicalis 15377 R-XTR-1602417 https://reactome.org/PathwayBrowser/#/R-XTR-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Xenopus tropicalis 15377 R-XTR-1602446 https://reactome.org/PathwayBrowser/#/R-XTR-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Xenopus tropicalis 15377 R-XTR-1605624 https://reactome.org/PathwayBrowser/#/R-XTR-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Xenopus tropicalis 15377 R-XTR-1605723 https://reactome.org/PathwayBrowser/#/R-XTR-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Xenopus tropicalis 15377 R-XTR-1605768 https://reactome.org/PathwayBrowser/#/R-XTR-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Xenopus tropicalis 15377 R-XTR-1605797 https://reactome.org/PathwayBrowser/#/R-XTR-1605797 SMPD1 hydrolyzes SPHM IEA Xenopus tropicalis 15377 R-XTR-1606273 https://reactome.org/PathwayBrowser/#/R-XTR-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Xenopus tropicalis 15377 R-XTR-1606583 https://reactome.org/PathwayBrowser/#/R-XTR-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Xenopus tropicalis 15377 R-XTR-1606839 https://reactome.org/PathwayBrowser/#/R-XTR-1606839 ARSC hydrolyzes steroid sulfates IEA Xenopus tropicalis 15377 R-XTR-1614544 https://reactome.org/PathwayBrowser/#/R-XTR-1614544 Sulfite is oxidized to sulfate IEA Xenopus tropicalis 15377 R-XTR-1614583 https://reactome.org/PathwayBrowser/#/R-XTR-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Xenopus tropicalis 15377 R-XTR-1614605 https://reactome.org/PathwayBrowser/#/R-XTR-1614605 Persulfide sulfur is dioxygenated IEA Xenopus tropicalis 15377 R-XTR-1614614 https://reactome.org/PathwayBrowser/#/R-XTR-1614614 Cysteine is degraded to serine and H2S IEA Xenopus tropicalis 15377 R-XTR-1614631 https://reactome.org/PathwayBrowser/#/R-XTR-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Xenopus tropicalis 15377 R-XTR-162425 https://reactome.org/PathwayBrowser/#/R-XTR-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Xenopus tropicalis 15377 R-XTR-162857 https://reactome.org/PathwayBrowser/#/R-XTR-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Xenopus tropicalis 15377 R-XTR-1630304 https://reactome.org/PathwayBrowser/#/R-XTR-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Xenopus tropicalis 15377 R-XTR-1630306 https://reactome.org/PathwayBrowser/#/R-XTR-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Xenopus tropicalis 15377 R-XTR-163214 https://reactome.org/PathwayBrowser/#/R-XTR-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Xenopus tropicalis 15377 R-XTR-1638032 https://reactome.org/PathwayBrowser/#/R-XTR-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Xenopus tropicalis 15377 R-XTR-163820 https://reactome.org/PathwayBrowser/#/R-XTR-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Xenopus tropicalis 15377 R-XTR-1638821 https://reactome.org/PathwayBrowser/#/R-XTR-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Xenopus tropicalis 15377 R-XTR-1640164 https://reactome.org/PathwayBrowser/#/R-XTR-1640164 ENPP7 hydrolyzes sphingomyelin IEA Xenopus tropicalis 15377 R-XTR-1655453 https://reactome.org/PathwayBrowser/#/R-XTR-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Xenopus tropicalis 15377 R-XTR-1667005 https://reactome.org/PathwayBrowser/#/R-XTR-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Xenopus tropicalis 15377 R-XTR-1675795 https://reactome.org/PathwayBrowser/#/R-XTR-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Xenopus tropicalis 15377 R-XTR-1675824 https://reactome.org/PathwayBrowser/#/R-XTR-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Xenopus tropicalis 15377 R-XTR-1675836 https://reactome.org/PathwayBrowser/#/R-XTR-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1675949 https://reactome.org/PathwayBrowser/#/R-XTR-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1675988 https://reactome.org/PathwayBrowser/#/R-XTR-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1675994 https://reactome.org/PathwayBrowser/#/R-XTR-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1676065 https://reactome.org/PathwayBrowser/#/R-XTR-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Xenopus tropicalis 15377 R-XTR-1676105 https://reactome.org/PathwayBrowser/#/R-XTR-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Xenopus tropicalis 15377 R-XTR-1676141 https://reactome.org/PathwayBrowser/#/R-XTR-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Xenopus tropicalis 15377 R-XTR-1676149 https://reactome.org/PathwayBrowser/#/R-XTR-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1676162 https://reactome.org/PathwayBrowser/#/R-XTR-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Xenopus tropicalis 15377 R-XTR-1676164 https://reactome.org/PathwayBrowser/#/R-XTR-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1676177 https://reactome.org/PathwayBrowser/#/R-XTR-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1676203 https://reactome.org/PathwayBrowser/#/R-XTR-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1676204 https://reactome.org/PathwayBrowser/#/R-XTR-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Xenopus tropicalis 15377 R-XTR-1678650 https://reactome.org/PathwayBrowser/#/R-XTR-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Xenopus tropicalis 15377 R-XTR-1678708 https://reactome.org/PathwayBrowser/#/R-XTR-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Xenopus tropicalis 15377 R-XTR-1678716 https://reactome.org/PathwayBrowser/#/R-XTR-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Xenopus tropicalis 15377 R-XTR-1678854 https://reactome.org/PathwayBrowser/#/R-XTR-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Xenopus tropicalis 15377 R-XTR-170153 https://reactome.org/PathwayBrowser/#/R-XTR-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Xenopus tropicalis 15377 R-XTR-170158 https://reactome.org/PathwayBrowser/#/R-XTR-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Xenopus tropicalis 15377 R-XTR-170161 https://reactome.org/PathwayBrowser/#/R-XTR-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Xenopus tropicalis 15377 R-XTR-173597 https://reactome.org/PathwayBrowser/#/R-XTR-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Xenopus tropicalis 15377 R-XTR-173739 https://reactome.org/PathwayBrowser/#/R-XTR-173739 Spontaneous hydrolysis of C3 thioester IEA Xenopus tropicalis 15377 R-XTR-174110 https://reactome.org/PathwayBrowser/#/R-XTR-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Xenopus tropicalis 15377 R-XTR-174124 https://reactome.org/PathwayBrowser/#/R-XTR-174124 Dephosphorylation of phospho-Cdh1 IEA Xenopus tropicalis 15377 R-XTR-174391 https://reactome.org/PathwayBrowser/#/R-XTR-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Xenopus tropicalis 15377 R-XTR-174401 https://reactome.org/PathwayBrowser/#/R-XTR-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Xenopus tropicalis 15377 R-XTR-174439 https://reactome.org/PathwayBrowser/#/R-XTR-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Xenopus tropicalis 15377 R-XTR-176606 https://reactome.org/PathwayBrowser/#/R-XTR-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Xenopus tropicalis 15377 R-XTR-177924 https://reactome.org/PathwayBrowser/#/R-XTR-177924 Dephosphorylation of Gab1 by SHP2 IEA Xenopus tropicalis 15377 R-XTR-177926 https://reactome.org/PathwayBrowser/#/R-XTR-177926 Dephosphorylation of PAG by SHP2 IEA Xenopus tropicalis 15377 R-XTR-177935 https://reactome.org/PathwayBrowser/#/R-XTR-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Xenopus tropicalis 15377 R-XTR-1793182 https://reactome.org/PathwayBrowser/#/R-XTR-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Xenopus tropicalis 15377 R-XTR-1793186 https://reactome.org/PathwayBrowser/#/R-XTR-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Xenopus tropicalis 15377 R-XTR-1793209 https://reactome.org/PathwayBrowser/#/R-XTR-1793209 HYAL1 hydrolyses Chondroitin chains IEA Xenopus tropicalis 15377 R-XTR-1855154 https://reactome.org/PathwayBrowser/#/R-XTR-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855159 https://reactome.org/PathwayBrowser/#/R-XTR-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855163 https://reactome.org/PathwayBrowser/#/R-XTR-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Xenopus tropicalis 15377 R-XTR-1855165 https://reactome.org/PathwayBrowser/#/R-XTR-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855166 https://reactome.org/PathwayBrowser/#/R-XTR-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855171 https://reactome.org/PathwayBrowser/#/R-XTR-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855174 https://reactome.org/PathwayBrowser/#/R-XTR-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855177 https://reactome.org/PathwayBrowser/#/R-XTR-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1855180 https://reactome.org/PathwayBrowser/#/R-XTR-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855198 https://reactome.org/PathwayBrowser/#/R-XTR-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855200 https://reactome.org/PathwayBrowser/#/R-XTR-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Xenopus tropicalis 15377 R-XTR-1855202 https://reactome.org/PathwayBrowser/#/R-XTR-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855205 https://reactome.org/PathwayBrowser/#/R-XTR-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855210 https://reactome.org/PathwayBrowser/#/R-XTR-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855211 https://reactome.org/PathwayBrowser/#/R-XTR-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855213 https://reactome.org/PathwayBrowser/#/R-XTR-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1855214 https://reactome.org/PathwayBrowser/#/R-XTR-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Xenopus tropicalis 15377 R-XTR-1855218 https://reactome.org/PathwayBrowser/#/R-XTR-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855219 https://reactome.org/PathwayBrowser/#/R-XTR-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 15377 R-XTR-1855221 https://reactome.org/PathwayBrowser/#/R-XTR-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1855222 https://reactome.org/PathwayBrowser/#/R-XTR-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-1855225 https://reactome.org/PathwayBrowser/#/R-XTR-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Xenopus tropicalis 15377 R-XTR-188979 https://reactome.org/PathwayBrowser/#/R-XTR-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Xenopus tropicalis 15377 R-XTR-189062 https://reactome.org/PathwayBrowser/#/R-XTR-189062 lactose + H2O => D-glucose + D-galactose IEA Xenopus tropicalis 15377 R-XTR-189398 https://reactome.org/PathwayBrowser/#/R-XTR-189398 HMOX1 dimer, HMOX2 cleave heme IEA Xenopus tropicalis 15377 R-XTR-189406 https://reactome.org/PathwayBrowser/#/R-XTR-189406 4 PBGs bind to form HMB IEA Xenopus tropicalis 15377 R-XTR-189421 https://reactome.org/PathwayBrowser/#/R-XTR-189421 CPO transforms COPRO3 to PPGEN9 IEA Xenopus tropicalis 15377 R-XTR-189439 https://reactome.org/PathwayBrowser/#/R-XTR-189439 ALAD condenses 2 dALAs to form PBG IEA Xenopus tropicalis 15377 R-XTR-189488 https://reactome.org/PathwayBrowser/#/R-XTR-189488 UROS transforms HMB to URO3 IEA Xenopus tropicalis 15377 R-XTR-191114 https://reactome.org/PathwayBrowser/#/R-XTR-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Xenopus tropicalis 15377 R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 15377 R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 15377 R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 15377 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 15377 R-XTR-192061 https://reactome.org/PathwayBrowser/#/R-XTR-192061 CYP46A1 24-hydroxylates CHOL IEA Xenopus tropicalis 15377 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 15377 R-XTR-192157 https://reactome.org/PathwayBrowser/#/R-XTR-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Xenopus tropicalis 15377 R-XTR-192178 https://reactome.org/PathwayBrowser/#/R-XTR-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Xenopus tropicalis 15377 R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 15377 R-XTR-192422 https://reactome.org/PathwayBrowser/#/R-XTR-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis 15377 R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 15377 R-XTR-192430 https://reactome.org/PathwayBrowser/#/R-XTR-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 15377 R-XTR-192434 https://reactome.org/PathwayBrowser/#/R-XTR-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis 15377 R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 15377 R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 15377 R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 15377 R-XTR-193068 https://reactome.org/PathwayBrowser/#/R-XTR-193068 CYP17A1 17-hydroxylates PREG IEA Xenopus tropicalis 15377 R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 15377 R-XTR-193072 https://reactome.org/PathwayBrowser/#/R-XTR-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Xenopus tropicalis 15377 R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 15377 R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 15377 R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 15377 R-XTR-193385 https://reactome.org/PathwayBrowser/#/R-XTR-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Xenopus tropicalis 15377 R-XTR-193709 https://reactome.org/PathwayBrowser/#/R-XTR-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Xenopus tropicalis 15377 R-XTR-193711 https://reactome.org/PathwayBrowser/#/R-XTR-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 15377 R-XTR-193727 https://reactome.org/PathwayBrowser/#/R-XTR-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 15377 R-XTR-193743 https://reactome.org/PathwayBrowser/#/R-XTR-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 15377 R-XTR-193766 https://reactome.org/PathwayBrowser/#/R-XTR-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 15377 R-XTR-193845 https://reactome.org/PathwayBrowser/#/R-XTR-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Xenopus tropicalis 15377 R-XTR-193965 https://reactome.org/PathwayBrowser/#/R-XTR-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Xenopus tropicalis 15377 R-XTR-193995 https://reactome.org/PathwayBrowser/#/R-XTR-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Xenopus tropicalis 15377 R-XTR-193997 https://reactome.org/PathwayBrowser/#/R-XTR-193997 CYP11B1 oxidises 11DCORT IEA Xenopus tropicalis 15377 R-XTR-194017 https://reactome.org/PathwayBrowser/#/R-XTR-194017 CYP11B2 oxidises 11DCORST to CORST IEA Xenopus tropicalis 15377 R-XTR-194641 https://reactome.org/PathwayBrowser/#/R-XTR-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 15377 R-XTR-194669 https://reactome.org/PathwayBrowser/#/R-XTR-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 15377 R-XTR-195664 https://reactome.org/PathwayBrowser/#/R-XTR-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Xenopus tropicalis 15377 R-XTR-196955 https://reactome.org/PathwayBrowser/#/R-XTR-196955 2xENPP1 hydrolyzes FAD to FMN IEA Xenopus tropicalis 15377 R-XTR-199456 https://reactome.org/PathwayBrowser/#/R-XTR-199456 PTEN dephosphorylates PIP3 IEA Xenopus tropicalis 15377 R-XTR-2002466 https://reactome.org/PathwayBrowser/#/R-XTR-2002466 Formation of allysine by LOX IEA Xenopus tropicalis 15377 R-XTR-200661 https://reactome.org/PathwayBrowser/#/R-XTR-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Xenopus tropicalis 15377 R-XTR-200740 https://reactome.org/PathwayBrowser/#/R-XTR-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Xenopus tropicalis 15377 R-XTR-201035 https://reactome.org/PathwayBrowser/#/R-XTR-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Xenopus tropicalis 15377 R-XTR-2022368 https://reactome.org/PathwayBrowser/#/R-XTR-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Xenopus tropicalis 15377 R-XTR-202237 https://reactome.org/PathwayBrowser/#/R-XTR-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Xenopus tropicalis 15377 R-XTR-2022378 https://reactome.org/PathwayBrowser/#/R-XTR-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Xenopus tropicalis 15377 R-XTR-2022379 https://reactome.org/PathwayBrowser/#/R-XTR-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Xenopus tropicalis 15377 R-XTR-2022381 https://reactome.org/PathwayBrowser/#/R-XTR-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 15377 R-XTR-2022383 https://reactome.org/PathwayBrowser/#/R-XTR-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 15377 R-XTR-2022396 https://reactome.org/PathwayBrowser/#/R-XTR-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Xenopus tropicalis 15377 R-XTR-2022398 https://reactome.org/PathwayBrowser/#/R-XTR-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Xenopus tropicalis 15377 R-XTR-2022399 https://reactome.org/PathwayBrowser/#/R-XTR-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Xenopus tropicalis 15377 R-XTR-2022403 https://reactome.org/PathwayBrowser/#/R-XTR-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Xenopus tropicalis 15377 R-XTR-2022405 https://reactome.org/PathwayBrowser/#/R-XTR-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 15377 R-XTR-2022411 https://reactome.org/PathwayBrowser/#/R-XTR-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 15377 R-XTR-2022412 https://reactome.org/PathwayBrowser/#/R-XTR-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Xenopus tropicalis 15377 R-XTR-2022887 https://reactome.org/PathwayBrowser/#/R-XTR-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Xenopus tropicalis 15377 R-XTR-2023971 https://reactome.org/PathwayBrowser/#/R-XTR-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 15377 R-XTR-2023973 https://reactome.org/PathwayBrowser/#/R-XTR-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 15377 R-XTR-202407 https://reactome.org/PathwayBrowser/#/R-XTR-202407 PLC-gamma1 hydrolyses PIP2 IEA Xenopus tropicalis 15377 R-XTR-2028294 https://reactome.org/PathwayBrowser/#/R-XTR-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Xenopus tropicalis 15377 R-XTR-2029468 https://reactome.org/PathwayBrowser/#/R-XTR-2029468 Conversion of PA into DAG by PAP-1 IEA Xenopus tropicalis 15377 R-XTR-2029471 https://reactome.org/PathwayBrowser/#/R-XTR-2029471 Hydrolysis of PC to PA by PLD IEA Xenopus tropicalis 15377 R-XTR-2029475 https://reactome.org/PathwayBrowser/#/R-XTR-2029475 Production of AA by iPLA2 upon FCGR activation IEA Xenopus tropicalis 15377 R-XTR-203797 https://reactome.org/PathwayBrowser/#/R-XTR-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Xenopus tropicalis 15377 R-XTR-2046083 https://reactome.org/PathwayBrowser/#/R-XTR-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-2046088 https://reactome.org/PathwayBrowser/#/R-XTR-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-2046089 https://reactome.org/PathwayBrowser/#/R-XTR-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-2046090 https://reactome.org/PathwayBrowser/#/R-XTR-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-2046092 https://reactome.org/PathwayBrowser/#/R-XTR-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-2046094 https://reactome.org/PathwayBrowser/#/R-XTR-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-2046095 https://reactome.org/PathwayBrowser/#/R-XTR-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-2046100 https://reactome.org/PathwayBrowser/#/R-XTR-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-204662 https://reactome.org/PathwayBrowser/#/R-XTR-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Xenopus tropicalis 15377 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 15377 R-XTR-2065357 https://reactome.org/PathwayBrowser/#/R-XTR-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Xenopus tropicalis 15377 R-XTR-2066779 https://reactome.org/PathwayBrowser/#/R-XTR-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Xenopus tropicalis 15377 R-XTR-2090037 https://reactome.org/PathwayBrowser/#/R-XTR-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Xenopus tropicalis 15377 R-XTR-2090043 https://reactome.org/PathwayBrowser/#/R-XTR-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Xenopus tropicalis 15377 R-XTR-2090079 https://reactome.org/PathwayBrowser/#/R-XTR-2090079 GLB1 hydrolyses linker chain(2) IEA Xenopus tropicalis 15377 R-XTR-209845 https://reactome.org/PathwayBrowser/#/R-XTR-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Xenopus tropicalis 15377 R-XTR-209891 https://reactome.org/PathwayBrowser/#/R-XTR-209891 Dopamine is oxidised to noradrenaline IEA Xenopus tropicalis 15377 R-XTR-211873 https://reactome.org/PathwayBrowser/#/R-XTR-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Xenopus tropicalis 15377 R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 15377 R-XTR-211881 https://reactome.org/PathwayBrowser/#/R-XTR-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Xenopus tropicalis 15377 R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 15377 R-XTR-211904 https://reactome.org/PathwayBrowser/#/R-XTR-211904 CYP4F12 18-hydroxylates ARA IEA Xenopus tropicalis 15377 R-XTR-211919 https://reactome.org/PathwayBrowser/#/R-XTR-211919 CYP4F8 19-hydroxylates PGH2 IEA Xenopus tropicalis 15377 R-XTR-211923 https://reactome.org/PathwayBrowser/#/R-XTR-211923 CYP26C1 4-hydroxylates 9cRA IEA Xenopus tropicalis 15377 R-XTR-211924 https://reactome.org/PathwayBrowser/#/R-XTR-211924 CYP4B1 12-hydroxylates ARA IEA Xenopus tropicalis 15377 R-XTR-211948 https://reactome.org/PathwayBrowser/#/R-XTR-211948 CYP3A4 can N-demethylate loperamide IEA Xenopus tropicalis 15377 R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 15377 R-XTR-211960 https://reactome.org/PathwayBrowser/#/R-XTR-211960 CYP2U1 19-hydroxylates ARA IEA Xenopus tropicalis 15377 R-XTR-211962 https://reactome.org/PathwayBrowser/#/R-XTR-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Xenopus tropicalis 15377 R-XTR-211966 https://reactome.org/PathwayBrowser/#/R-XTR-211966 CYP2D6 4-hydroxylates debrisoquine IEA Xenopus tropicalis 15377 R-XTR-211968 https://reactome.org/PathwayBrowser/#/R-XTR-211968 CYP2W1 oxidises INDOL IEA Xenopus tropicalis 15377 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 15377 R-XTR-211991 https://reactome.org/PathwayBrowser/#/R-XTR-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Xenopus tropicalis 15377 R-XTR-212005 https://reactome.org/PathwayBrowser/#/R-XTR-212005 CYP2F1 dehydrogenates 3-methylindole IEA Xenopus tropicalis 15377 R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 15377 R-XTR-213175 https://reactome.org/PathwayBrowser/#/R-XTR-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 15377 R-XTR-215526 https://reactome.org/PathwayBrowser/#/R-XTR-215526 CYP4F3 20-hydroxylates LTB4 IEA Xenopus tropicalis 15377 R-XTR-2160492 https://reactome.org/PathwayBrowser/#/R-XTR-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Xenopus tropicalis 15377 R-XTR-2160874 https://reactome.org/PathwayBrowser/#/R-XTR-2160874 HYAL1 hydrolyses (HA)50 IEA Xenopus tropicalis 15377 R-XTR-2161187 https://reactome.org/PathwayBrowser/#/R-XTR-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Xenopus tropicalis 15377 R-XTR-2161195 https://reactome.org/PathwayBrowser/#/R-XTR-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Xenopus tropicalis 15377 R-XTR-2161745 https://reactome.org/PathwayBrowser/#/R-XTR-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 15377 R-XTR-2161792 https://reactome.org/PathwayBrowser/#/R-XTR-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 15377 R-XTR-2161814 https://reactome.org/PathwayBrowser/#/R-XTR-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Xenopus tropicalis 15377 R-XTR-2161890 https://reactome.org/PathwayBrowser/#/R-XTR-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Xenopus tropicalis 15377 R-XTR-2161899 https://reactome.org/PathwayBrowser/#/R-XTR-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Xenopus tropicalis 15377 R-XTR-2161940 https://reactome.org/PathwayBrowser/#/R-XTR-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Xenopus tropicalis 15377 R-XTR-2161951 https://reactome.org/PathwayBrowser/#/R-XTR-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Xenopus tropicalis 15377 R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Xenopus tropicalis 15377 R-XTR-2162194 https://reactome.org/PathwayBrowser/#/R-XTR-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Xenopus tropicalis 15377 R-XTR-2162226 https://reactome.org/PathwayBrowser/#/R-XTR-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Xenopus tropicalis 15377 R-XTR-2162227 https://reactome.org/PathwayBrowser/#/R-XTR-2162227 GUSB tetramer hydrolyses (HA)2 IEA Xenopus tropicalis 15377 R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 15377 R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 15377 R-XTR-2187401 https://reactome.org/PathwayBrowser/#/R-XTR-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Xenopus tropicalis 15377 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 15377 R-XTR-2393939 https://reactome.org/PathwayBrowser/#/R-XTR-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 15377 R-XTR-2393954 https://reactome.org/PathwayBrowser/#/R-XTR-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 15377 R-XTR-2395340 https://reactome.org/PathwayBrowser/#/R-XTR-2395340 Formation of hydroxyallysine by LOX IEA Xenopus tropicalis 15377 R-XTR-2395818 https://reactome.org/PathwayBrowser/#/R-XTR-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Xenopus tropicalis 15377 R-XTR-2395849 https://reactome.org/PathwayBrowser/#/R-XTR-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 15377 R-XTR-2395869 https://reactome.org/PathwayBrowser/#/R-XTR-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 15377 R-XTR-2395872 https://reactome.org/PathwayBrowser/#/R-XTR-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Xenopus tropicalis 15377 R-XTR-2395873 https://reactome.org/PathwayBrowser/#/R-XTR-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Xenopus tropicalis 15377 R-XTR-2395876 https://reactome.org/PathwayBrowser/#/R-XTR-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 15377 R-XTR-2395879 https://reactome.org/PathwayBrowser/#/R-XTR-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 15377 R-XTR-2395965 https://reactome.org/PathwayBrowser/#/R-XTR-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Xenopus tropicalis 15377 R-XTR-2408551 https://reactome.org/PathwayBrowser/#/R-XTR-2408551 SeMet is converted to AdoSeMet by MAT IEA Xenopus tropicalis 15377 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 15377 R-XTR-2465924 https://reactome.org/PathwayBrowser/#/R-XTR-2465924 OPN1LW binds 11cRAL IEA Xenopus tropicalis 15377 R-XTR-2466085 https://reactome.org/PathwayBrowser/#/R-XTR-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Xenopus tropicalis 15377 R-XTR-2509793 https://reactome.org/PathwayBrowser/#/R-XTR-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Xenopus tropicalis 15377 R-XTR-2509816 https://reactome.org/PathwayBrowser/#/R-XTR-2509816 NUDT16 hydrolyses IDP to IMP IEA Xenopus tropicalis 15377 R-XTR-2509827 https://reactome.org/PathwayBrowser/#/R-XTR-2509827 ITPA hydrolyses ITP to IMP IEA Xenopus tropicalis 15377 R-XTR-2509831 https://reactome.org/PathwayBrowser/#/R-XTR-2509831 ITPA hydrolyses XTP to XMP IEA Xenopus tropicalis 15377 R-XTR-2509838 https://reactome.org/PathwayBrowser/#/R-XTR-2509838 ITPA hydrolyses dITP to dIMP IEA Xenopus tropicalis 15377 R-XTR-2584246 https://reactome.org/PathwayBrowser/#/R-XTR-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Xenopus tropicalis 15377 R-XTR-266051 https://reactome.org/PathwayBrowser/#/R-XTR-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Xenopus tropicalis 15377 R-XTR-266072 https://reactome.org/PathwayBrowser/#/R-XTR-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Xenopus tropicalis 15377 R-XTR-266082 https://reactome.org/PathwayBrowser/#/R-XTR-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Xenopus tropicalis 15377 R-XTR-2730847 https://reactome.org/PathwayBrowser/#/R-XTR-2730847 Hydrolysis of PIP2 by PLCG IEA Xenopus tropicalis 15377 R-XTR-2855047 https://reactome.org/PathwayBrowser/#/R-XTR-2855047 Hydrolysis of internal thioester in C4b IEA Xenopus tropicalis 15377 R-XTR-2995330 https://reactome.org/PathwayBrowser/#/R-XTR-2995330 COX10 transforms heme to heme O IEA Xenopus tropicalis 15377 R-XTR-2995334 https://reactome.org/PathwayBrowser/#/R-XTR-2995334 COX15 transforms heme O to heme A IEA Xenopus tropicalis 15377 R-XTR-3002811 https://reactome.org/PathwayBrowser/#/R-XTR-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Xenopus tropicalis 15377 R-XTR-3095901 https://reactome.org/PathwayBrowser/#/R-XTR-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Xenopus tropicalis 15377 R-XTR-3204311 https://reactome.org/PathwayBrowser/#/R-XTR-3204311 AOX1 oxidises PXL to PDXate IEA Xenopus tropicalis 15377 R-XTR-3322995 https://reactome.org/PathwayBrowser/#/R-XTR-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Xenopus tropicalis 15377 R-XTR-3341296 https://reactome.org/PathwayBrowser/#/R-XTR-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Xenopus tropicalis 15377 R-XTR-3343700 https://reactome.org/PathwayBrowser/#/R-XTR-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Xenopus tropicalis 15377 R-XTR-350604 https://reactome.org/PathwayBrowser/#/R-XTR-350604 Agmatine + H2O <=> putrescine + urea IEA Xenopus tropicalis 15377 R-XTR-3697894 https://reactome.org/PathwayBrowser/#/R-XTR-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Xenopus tropicalis 15377 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 15377 R-XTR-382560 https://reactome.org/PathwayBrowser/#/R-XTR-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Xenopus tropicalis 15377 R-XTR-382575 https://reactome.org/PathwayBrowser/#/R-XTR-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Xenopus tropicalis 15377 R-XTR-383190 https://reactome.org/PathwayBrowser/#/R-XTR-383190 HCO3- transport through ion channel IEA Xenopus tropicalis 15377 R-XTR-389821 https://reactome.org/PathwayBrowser/#/R-XTR-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Xenopus tropicalis 15377 R-XTR-389862 https://reactome.org/PathwayBrowser/#/R-XTR-389862 Conversion of glyoxylate to oxalate IEA Xenopus tropicalis 15377 R-XTR-390304 https://reactome.org/PathwayBrowser/#/R-XTR-390304 acetyl-CoA + H2O => acetate + CoASH IEA Xenopus tropicalis 15377 R-XTR-4084976 https://reactome.org/PathwayBrowser/#/R-XTR-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Xenopus tropicalis 15377 R-XTR-4084989 https://reactome.org/PathwayBrowser/#/R-XTR-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Xenopus tropicalis 15377 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 15377 R-XTR-4084999 https://reactome.org/PathwayBrowser/#/R-XTR-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 15377 R-XTR-4085021 https://reactome.org/PathwayBrowser/#/R-XTR-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Xenopus tropicalis 15377 R-XTR-4085029 https://reactome.org/PathwayBrowser/#/R-XTR-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 15377 R-XTR-4086392 https://reactome.org/PathwayBrowser/#/R-XTR-4086392 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 15377 R-XTR-4088141 https://reactome.org/PathwayBrowser/#/R-XTR-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Xenopus tropicalis 15377 R-XTR-4093339 https://reactome.org/PathwayBrowser/#/R-XTR-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Xenopus tropicalis 15377 R-XTR-416559 https://reactome.org/PathwayBrowser/#/R-XTR-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Xenopus tropicalis 15377 R-XTR-418553 https://reactome.org/PathwayBrowser/#/R-XTR-418553 cAMP degradation by Phosphodiesterases IEA Xenopus tropicalis 15377 R-XTR-426043 https://reactome.org/PathwayBrowser/#/R-XTR-426043 2-AG hydrolysis to arachidonate by MAGL IEA Xenopus tropicalis 15377 R-XTR-428205 https://reactome.org/PathwayBrowser/#/R-XTR-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Xenopus tropicalis 15377 R-XTR-428231 https://reactome.org/PathwayBrowser/#/R-XTR-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Xenopus tropicalis 15377 R-XTR-428259 https://reactome.org/PathwayBrowser/#/R-XTR-428259 DEGS1 dehydrogenates dihydroceramide IEA Xenopus tropicalis 15377 R-XTR-428260 https://reactome.org/PathwayBrowser/#/R-XTR-428260 DEGS2 oxygenates dihydroceramide IEA Xenopus tropicalis 15377 R-XTR-428262 https://reactome.org/PathwayBrowser/#/R-XTR-428262 ACER3 hydrolyzes phytoceramide IEA Xenopus tropicalis 15377 R-XTR-428664 https://reactome.org/PathwayBrowser/#/R-XTR-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Xenopus tropicalis 15377 R-XTR-428696 https://reactome.org/PathwayBrowser/#/R-XTR-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Xenopus tropicalis 15377 R-XTR-429860 https://reactome.org/PathwayBrowser/#/R-XTR-429860 DCP1-DCP2 complex decaps mRNA IEA Xenopus tropicalis 15377 R-XTR-429955 https://reactome.org/PathwayBrowser/#/R-XTR-429955 CCR4-NOT complex deadenylates mRNA IEA Xenopus tropicalis 15377 R-XTR-429961 https://reactome.org/PathwayBrowser/#/R-XTR-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Xenopus tropicalis 15377 R-XTR-429992 https://reactome.org/PathwayBrowser/#/R-XTR-429992 PARN deadenylates mRNA IEA Xenopus tropicalis 15377 R-XTR-430028 https://reactome.org/PathwayBrowser/#/R-XTR-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Xenopus tropicalis 15377 R-XTR-432010 https://reactome.org/PathwayBrowser/#/R-XTR-432010 Aquaporin-1 passively transports water into cell IEA Xenopus tropicalis 15377 R-XTR-432054 https://reactome.org/PathwayBrowser/#/R-XTR-432054 Aquaporin-1 passively transports water out of cell IEA Xenopus tropicalis 15377 R-XTR-432065 https://reactome.org/PathwayBrowser/#/R-XTR-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Xenopus tropicalis 15377 R-XTR-432067 https://reactome.org/PathwayBrowser/#/R-XTR-432067 Aquaporin-4 passively transports water out of cell IEA Xenopus tropicalis 15377 R-XTR-4419948 https://reactome.org/PathwayBrowser/#/R-XTR-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Xenopus tropicalis 15377 R-XTR-445714 https://reactome.org/PathwayBrowser/#/R-XTR-445714 Aquaporin-3 passively transports water out of cell IEA Xenopus tropicalis 15377 R-XTR-446200 https://reactome.org/PathwayBrowser/#/R-XTR-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Xenopus tropicalis 15377 R-XTR-452036 https://reactome.org/PathwayBrowser/#/R-XTR-452036 arginine + H2O => ornithine + urea [ARG2] IEA Xenopus tropicalis 15377 R-XTR-4641236 https://reactome.org/PathwayBrowser/#/R-XTR-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Xenopus tropicalis 15377 R-XTR-507868 https://reactome.org/PathwayBrowser/#/R-XTR-507868 Aquaporins passively transport water into cells IEA Xenopus tropicalis 15377 R-XTR-507870 https://reactome.org/PathwayBrowser/#/R-XTR-507870 Aquaporins passively transport water out of cells IEA Xenopus tropicalis 15377 R-XTR-508308 https://reactome.org/PathwayBrowser/#/R-XTR-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Xenopus tropicalis 15377 R-XTR-5221130 https://reactome.org/PathwayBrowser/#/R-XTR-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Xenopus tropicalis 15377 R-XTR-5251955 https://reactome.org/PathwayBrowser/#/R-XTR-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Xenopus tropicalis 15377 R-XTR-5251959 https://reactome.org/PathwayBrowser/#/R-XTR-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Xenopus tropicalis 15377 R-XTR-5251989 https://reactome.org/PathwayBrowser/#/R-XTR-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Xenopus tropicalis 15377 R-XTR-5362459 https://reactome.org/PathwayBrowser/#/R-XTR-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Xenopus tropicalis 15377 R-XTR-5362522 https://reactome.org/PathwayBrowser/#/R-XTR-5362522 ALDHs oxidise atRAL to atRA IEA Xenopus tropicalis 15377 R-XTR-5362525 https://reactome.org/PathwayBrowser/#/R-XTR-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Xenopus tropicalis 15377 R-XTR-5423647 https://reactome.org/PathwayBrowser/#/R-XTR-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Xenopus tropicalis 15377 R-XTR-5423664 https://reactome.org/PathwayBrowser/#/R-XTR-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Xenopus tropicalis 15377 R-XTR-5423672 https://reactome.org/PathwayBrowser/#/R-XTR-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Xenopus tropicalis 15377 R-XTR-5433074 https://reactome.org/PathwayBrowser/#/R-XTR-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 15377 R-XTR-548843 https://reactome.org/PathwayBrowser/#/R-XTR-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Xenopus tropicalis 15377 R-XTR-5602295 https://reactome.org/PathwayBrowser/#/R-XTR-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Xenopus tropicalis 15377 R-XTR-5603114 https://reactome.org/PathwayBrowser/#/R-XTR-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Xenopus tropicalis 15377 R-XTR-5607735 https://reactome.org/PathwayBrowser/#/R-XTR-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Xenopus tropicalis 15377 R-XTR-5628905 https://reactome.org/PathwayBrowser/#/R-XTR-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Xenopus tropicalis 15377 R-XTR-5631885 https://reactome.org/PathwayBrowser/#/R-XTR-5631885 PRDX1 overoxidizes IEA Xenopus tropicalis 15377 R-XTR-5649705 https://reactome.org/PathwayBrowser/#/R-XTR-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Xenopus tropicalis 15377 R-XTR-5651828 https://reactome.org/PathwayBrowser/#/R-XTR-5651828 PARG dePARylates PARP1,PARP2 IEA Xenopus tropicalis 15377 R-XTR-5653770 https://reactome.org/PathwayBrowser/#/R-XTR-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Xenopus tropicalis 15377 R-XTR-5662692 https://reactome.org/PathwayBrowser/#/R-XTR-5662692 Dopa is oxidized to dopaquinone by TYR IEA Xenopus tropicalis 15377 R-XTR-5675373 https://reactome.org/PathwayBrowser/#/R-XTR-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Xenopus tropicalis 15377 R-XTR-5675376 https://reactome.org/PathwayBrowser/#/R-XTR-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Xenopus tropicalis 15377 R-XTR-5675433 https://reactome.org/PathwayBrowser/#/R-XTR-5675433 PP5 dephosphorylates RAF1 S338 IEA Xenopus tropicalis 15377 R-XTR-5676637 https://reactome.org/PathwayBrowser/#/R-XTR-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Xenopus tropicalis 15377 R-XTR-5678863 https://reactome.org/PathwayBrowser/#/R-XTR-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-XTR-5679041 https://reactome.org/PathwayBrowser/#/R-XTR-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-XTR-5683714 https://reactome.org/PathwayBrowser/#/R-XTR-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Xenopus tropicalis 15377 R-XTR-5685902 https://reactome.org/PathwayBrowser/#/R-XTR-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Xenopus tropicalis 15377 R-XTR-5687758 https://reactome.org/PathwayBrowser/#/R-XTR-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Xenopus tropicalis 15377 R-XTR-5688797 https://reactome.org/PathwayBrowser/#/R-XTR-5688797 ATXN3 family cleave Ub chains IEA Xenopus tropicalis 15377 R-XTR-5689973 https://reactome.org/PathwayBrowser/#/R-XTR-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Xenopus tropicalis 15377 R-XTR-5690042 https://reactome.org/PathwayBrowser/#/R-XTR-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 15377 R-XTR-5690043 https://reactome.org/PathwayBrowser/#/R-XTR-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 15377 R-XTR-5690046 https://reactome.org/PathwayBrowser/#/R-XTR-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Xenopus tropicalis 15377 R-XTR-5690066 https://reactome.org/PathwayBrowser/#/R-XTR-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 15377 R-XTR-5690080 https://reactome.org/PathwayBrowser/#/R-XTR-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Xenopus tropicalis 15377 R-XTR-5690157 https://reactome.org/PathwayBrowser/#/R-XTR-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Xenopus tropicalis 15377 R-XTR-5690159 https://reactome.org/PathwayBrowser/#/R-XTR-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Xenopus tropicalis 15377 R-XTR-5690319 https://reactome.org/PathwayBrowser/#/R-XTR-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Xenopus tropicalis 15377 R-XTR-5690517 https://reactome.org/PathwayBrowser/#/R-XTR-5690517 PPT1 hydrolyses palmitoylated proteins IEA Xenopus tropicalis 15377 R-XTR-5690565 https://reactome.org/PathwayBrowser/#/R-XTR-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Xenopus tropicalis 15377 R-XTR-5690790 https://reactome.org/PathwayBrowser/#/R-XTR-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Xenopus tropicalis 15377 R-XTR-5690808 https://reactome.org/PathwayBrowser/#/R-XTR-5690808 UCHL3, SENP8 cleave NEDD8 IEA Xenopus tropicalis 15377 R-XTR-5690870 https://reactome.org/PathwayBrowser/#/R-XTR-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Xenopus tropicalis 15377 R-XTR-5691381 https://reactome.org/PathwayBrowser/#/R-XTR-5691381 MYSM1 deubiquitinates Histone H2A IEA Xenopus tropicalis 15377 R-XTR-5691411 https://reactome.org/PathwayBrowser/#/R-XTR-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Xenopus tropicalis 15377 R-XTR-5691439 https://reactome.org/PathwayBrowser/#/R-XTR-5691439 BRISC complex deubiquitinates NLRP3 IEA Xenopus tropicalis 15377 R-XTR-5691507 https://reactome.org/PathwayBrowser/#/R-XTR-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Xenopus tropicalis 15377 R-XTR-5691512 https://reactome.org/PathwayBrowser/#/R-XTR-5691512 APEH hydrolyses NAc-Ser-protein IEA Xenopus tropicalis 15377 R-XTR-5692462 https://reactome.org/PathwayBrowser/#/R-XTR-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Xenopus tropicalis 15377 R-XTR-5692480 https://reactome.org/PathwayBrowser/#/R-XTR-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Xenopus tropicalis 15377 R-XTR-5692754 https://reactome.org/PathwayBrowser/#/R-XTR-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Xenopus tropicalis 15377 R-XTR-5693346 https://reactome.org/PathwayBrowser/#/R-XTR-5693346 CECRI deaminates Ade-Rib to Ino IEA Xenopus tropicalis 15377 R-XTR-5693373 https://reactome.org/PathwayBrowser/#/R-XTR-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Xenopus tropicalis 15377 R-XTR-5693691 https://reactome.org/PathwayBrowser/#/R-XTR-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Xenopus tropicalis 15377 R-XTR-5693724 https://reactome.org/PathwayBrowser/#/R-XTR-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Xenopus tropicalis 15377 R-XTR-5693742 https://reactome.org/PathwayBrowser/#/R-XTR-5693742 FAAH hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 15377 R-XTR-5693751 https://reactome.org/PathwayBrowser/#/R-XTR-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 15377 R-XTR-5693761 https://reactome.org/PathwayBrowser/#/R-XTR-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Xenopus tropicalis 15377 R-XTR-5693807 https://reactome.org/PathwayBrowser/#/R-XTR-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Xenopus tropicalis 15377 R-XTR-5694109 https://reactome.org/PathwayBrowser/#/R-XTR-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Xenopus tropicalis 15377 R-XTR-5694126 https://reactome.org/PathwayBrowser/#/R-XTR-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Xenopus tropicalis 15377 R-XTR-5694137 https://reactome.org/PathwayBrowser/#/R-XTR-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Xenopus tropicalis 15377 R-XTR-5694421 https://reactome.org/PathwayBrowser/#/R-XTR-5694421 PP6 dephosphorylates SEC24 IEA Xenopus tropicalis 15377 R-XTR-5694462 https://reactome.org/PathwayBrowser/#/R-XTR-5694462 ABHD6,12 hydrolyse 3AG IEA Xenopus tropicalis 15377 R-XTR-5694485 https://reactome.org/PathwayBrowser/#/R-XTR-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Xenopus tropicalis 15377 R-XTR-5694563 https://reactome.org/PathwayBrowser/#/R-XTR-5694563 ABHD10 hydrolyses MPAG IEA Xenopus tropicalis 15377 R-XTR-5694583 https://reactome.org/PathwayBrowser/#/R-XTR-5694583 ABHD4 hydrolyses NAPE IEA Xenopus tropicalis 15377 R-XTR-5695964 https://reactome.org/PathwayBrowser/#/R-XTR-5695964 ABHD14B hydrolyses PNPB IEA Xenopus tropicalis 15377 R-XTR-5696049 https://reactome.org/PathwayBrowser/#/R-XTR-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 15377 R-XTR-5696080 https://reactome.org/PathwayBrowser/#/R-XTR-5696080 ALDH3B1 oxidises HXAL to PALM IEA Xenopus tropicalis 15377 R-XTR-5696091 https://reactome.org/PathwayBrowser/#/R-XTR-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Xenopus tropicalis 15377 R-XTR-5696101 https://reactome.org/PathwayBrowser/#/R-XTR-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Xenopus tropicalis 15377 R-XTR-5696119 https://reactome.org/PathwayBrowser/#/R-XTR-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Xenopus tropicalis 15377 R-XTR-5696131 https://reactome.org/PathwayBrowser/#/R-XTR-5696131 AOC1 deaminates Hist IEA Xenopus tropicalis 15377 R-XTR-5696183 https://reactome.org/PathwayBrowser/#/R-XTR-5696183 AOC3 deaminates BZAM IEA Xenopus tropicalis 15377 R-XTR-5696197 https://reactome.org/PathwayBrowser/#/R-XTR-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Xenopus tropicalis 15377 R-XTR-5696230 https://reactome.org/PathwayBrowser/#/R-XTR-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Xenopus tropicalis 15377 R-XTR-5696415 https://reactome.org/PathwayBrowser/#/R-XTR-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Xenopus tropicalis 15377 R-XTR-5696534 https://reactome.org/PathwayBrowser/#/R-XTR-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Xenopus tropicalis 15377 R-XTR-5696564 https://reactome.org/PathwayBrowser/#/R-XTR-5696564 USP25 deubiquitinates DDX58 IEA Xenopus tropicalis 15377 R-XTR-5696600 https://reactome.org/PathwayBrowser/#/R-XTR-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Xenopus tropicalis 15377 R-XTR-5696605 https://reactome.org/PathwayBrowser/#/R-XTR-5696605 USP12, USP26 deubiquitinate AR IEA Xenopus tropicalis 15377 R-XTR-5696872 https://reactome.org/PathwayBrowser/#/R-XTR-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Xenopus tropicalis 15377 R-XTR-5696945 https://reactome.org/PathwayBrowser/#/R-XTR-5696945 USP33 deubiquitinates CCP110,ARRB IEA Xenopus tropicalis 15377 R-XTR-5696947 https://reactome.org/PathwayBrowser/#/R-XTR-5696947 USP47 deubiquitinates POLB IEA Xenopus tropicalis 15377 R-XTR-5696958 https://reactome.org/PathwayBrowser/#/R-XTR-5696958 USP44 deubiquitinates CDC20 IEA Xenopus tropicalis 15377 R-XTR-5696960 https://reactome.org/PathwayBrowser/#/R-XTR-5696960 USP49 deubiquitinates H2B IEA Xenopus tropicalis 15377 R-XTR-5696968 https://reactome.org/PathwayBrowser/#/R-XTR-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Xenopus tropicalis 15377 R-XTR-5696997 https://reactome.org/PathwayBrowser/#/R-XTR-5696997 USP24 deubiquitinates DDB2 IEA Xenopus tropicalis 15377 R-XTR-5697009 https://reactome.org/PathwayBrowser/#/R-XTR-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Xenopus tropicalis 15377 R-XTR-6781764 https://reactome.org/PathwayBrowser/#/R-XTR-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Xenopus tropicalis 15377 R-XTR-6782069 https://reactome.org/PathwayBrowser/#/R-XTR-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Xenopus tropicalis 15377 R-XTR-6782106 https://reactome.org/PathwayBrowser/#/R-XTR-6782106 USP10 deubiquitinates SNX3, CFTR IEA Xenopus tropicalis 15377 R-XTR-6782628 https://reactome.org/PathwayBrowser/#/R-XTR-6782628 USP8 deubiquitinates STAM2:HGS IEA Xenopus tropicalis 15377 R-XTR-6783177 https://reactome.org/PathwayBrowser/#/R-XTR-6783177 USP21 deubiquitinates GATA3,IL33 IEA Xenopus tropicalis 15377 R-XTR-6783221 https://reactome.org/PathwayBrowser/#/R-XTR-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Xenopus tropicalis 15377 R-XTR-6786190 https://reactome.org/PathwayBrowser/#/R-XTR-6786190 CMBL hydrolyses OM to OLMS IEA Xenopus tropicalis 15377 R-XTR-6786239 https://reactome.org/PathwayBrowser/#/R-XTR-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Xenopus tropicalis 15377 R-XTR-6786650 https://reactome.org/PathwayBrowser/#/R-XTR-6786650 DDHD1,2 hydrolyse PA IEA Xenopus tropicalis 15377 R-XTR-6787632 https://reactome.org/PathwayBrowser/#/R-XTR-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Xenopus tropicalis 15377 R-XTR-6788295 https://reactome.org/PathwayBrowser/#/R-XTR-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Xenopus tropicalis 15377 R-XTR-6788912 https://reactome.org/PathwayBrowser/#/R-XTR-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Xenopus tropicalis 15377 R-XTR-6792445 https://reactome.org/PathwayBrowser/#/R-XTR-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Xenopus tropicalis 15377 R-XTR-6792863 https://reactome.org/PathwayBrowser/#/R-XTR-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Xenopus tropicalis 15377 R-XTR-6797627 https://reactome.org/PathwayBrowser/#/R-XTR-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Xenopus tropicalis 15377 R-XTR-6797630 https://reactome.org/PathwayBrowser/#/R-XTR-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Xenopus tropicalis 15377 R-XTR-6797955 https://reactome.org/PathwayBrowser/#/R-XTR-6797955 ALDH7A1 oxidises BETALD to BET IEA Xenopus tropicalis 15377 R-XTR-6799545 https://reactome.org/PathwayBrowser/#/R-XTR-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Xenopus tropicalis 15377 R-XTR-6799581 https://reactome.org/PathwayBrowser/#/R-XTR-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Xenopus tropicalis 15377 R-XTR-6799604 https://reactome.org/PathwayBrowser/#/R-XTR-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Xenopus tropicalis 15377 R-XTR-6799977 https://reactome.org/PathwayBrowser/#/R-XTR-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Xenopus tropicalis 15377 R-XTR-6800198 https://reactome.org/PathwayBrowser/#/R-XTR-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Xenopus tropicalis 15377 R-XTR-6800200 https://reactome.org/PathwayBrowser/#/R-XTR-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Xenopus tropicalis 15377 R-XTR-6801462 https://reactome.org/PathwayBrowser/#/R-XTR-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Xenopus tropicalis 15377 R-XTR-6803545 https://reactome.org/PathwayBrowser/#/R-XTR-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Xenopus tropicalis 15377 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 15377 R-XTR-6803789 https://reactome.org/PathwayBrowser/#/R-XTR-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Xenopus tropicalis 15377 R-XTR-6805650 https://reactome.org/PathwayBrowser/#/R-XTR-6805650 MTA2-NuRD complex deacetylates TP53 IEA Xenopus tropicalis 15377 R-XTR-6807027 https://reactome.org/PathwayBrowser/#/R-XTR-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Xenopus tropicalis 15377 R-XTR-6807053 https://reactome.org/PathwayBrowser/#/R-XTR-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Xenopus tropicalis 15377 R-XTR-6807206 https://reactome.org/PathwayBrowser/#/R-XTR-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Xenopus tropicalis 15377 R-XTR-6807214 https://reactome.org/PathwayBrowser/#/R-XTR-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Xenopus tropicalis 15377 R-XTR-6808464 https://reactome.org/PathwayBrowser/#/R-XTR-6808464 ALDH3B2 oxidises HXAL to PALM IEA Xenopus tropicalis 15377 R-XTR-6808487 https://reactome.org/PathwayBrowser/#/R-XTR-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 15377 R-XTR-6808496 https://reactome.org/PathwayBrowser/#/R-XTR-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 15377 R-XTR-6809263 https://reactome.org/PathwayBrowser/#/R-XTR-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-6809287 https://reactome.org/PathwayBrowser/#/R-XTR-6809287 NUDT12 hydrolyses NADH to NMNH IEA Xenopus tropicalis 15377 R-XTR-6809720 https://reactome.org/PathwayBrowser/#/R-XTR-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Xenopus tropicalis 15377 R-XTR-6810410 https://reactome.org/PathwayBrowser/#/R-XTR-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Xenopus tropicalis 15377 R-XTR-6810472 https://reactome.org/PathwayBrowser/#/R-XTR-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Xenopus tropicalis 15377 R-XTR-6810474 https://reactome.org/PathwayBrowser/#/R-XTR-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Xenopus tropicalis 15377 R-XTR-6813740 https://reactome.org/PathwayBrowser/#/R-XTR-6813740 GDE1 hydrolyzes GroPIns IEA Xenopus tropicalis 15377 R-XTR-6813749 https://reactome.org/PathwayBrowser/#/R-XTR-6813749 ALDH1A1 oxidises GA to DGA IEA Xenopus tropicalis 15377 R-XTR-6814797 https://reactome.org/PathwayBrowser/#/R-XTR-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Xenopus tropicalis 15377 R-XTR-69199 https://reactome.org/PathwayBrowser/#/R-XTR-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Xenopus tropicalis 15377 R-XTR-70479 https://reactome.org/PathwayBrowser/#/R-XTR-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Xenopus tropicalis 15377 R-XTR-70494 https://reactome.org/PathwayBrowser/#/R-XTR-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Xenopus tropicalis 15377 R-XTR-70569 https://reactome.org/PathwayBrowser/#/R-XTR-70569 arginine + H2O => ornithine + urea [ARG1] IEA Xenopus tropicalis 15377 R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Xenopus tropicalis 15377 R-XTR-70599 https://reactome.org/PathwayBrowser/#/R-XTR-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Xenopus tropicalis 15377 R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Xenopus tropicalis 15377 R-XTR-70609 https://reactome.org/PathwayBrowser/#/R-XTR-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Xenopus tropicalis 15377 R-XTR-70679 https://reactome.org/PathwayBrowser/#/R-XTR-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Xenopus tropicalis 15377 R-XTR-70785 https://reactome.org/PathwayBrowser/#/R-XTR-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Xenopus tropicalis 15377 R-XTR-70870 https://reactome.org/PathwayBrowser/#/R-XTR-70870 ECHS1 hydrates methacrylyl-CoA IEA Xenopus tropicalis 15377 R-XTR-70903 https://reactome.org/PathwayBrowser/#/R-XTR-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Xenopus tropicalis 15377 R-XTR-70906 https://reactome.org/PathwayBrowser/#/R-XTR-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Xenopus tropicalis 15377 R-XTR-70938 https://reactome.org/PathwayBrowser/#/R-XTR-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Xenopus tropicalis 15377 R-XTR-70940 https://reactome.org/PathwayBrowser/#/R-XTR-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Xenopus tropicalis 15377 R-XTR-70941 https://reactome.org/PathwayBrowser/#/R-XTR-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Xenopus tropicalis 15377 R-XTR-70975 https://reactome.org/PathwayBrowser/#/R-XTR-70975 CS acetylates OA to citrate IEA Xenopus tropicalis 15377 R-XTR-71146 https://reactome.org/PathwayBrowser/#/R-XTR-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Xenopus tropicalis 15377 R-XTR-71181 https://reactome.org/PathwayBrowser/#/R-XTR-71181 FAH cleaves 4FAA IEA Xenopus tropicalis 15377 R-XTR-71200 https://reactome.org/PathwayBrowser/#/R-XTR-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Xenopus tropicalis 15377 R-XTR-71217 https://reactome.org/PathwayBrowser/#/R-XTR-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Xenopus tropicalis 15377 R-XTR-71260 https://reactome.org/PathwayBrowser/#/R-XTR-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Xenopus tropicalis 15377 R-XTR-71296 https://reactome.org/PathwayBrowser/#/R-XTR-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Xenopus tropicalis 15377 R-XTR-71660 https://reactome.org/PathwayBrowser/#/R-XTR-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Xenopus tropicalis 15377 R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 15377 R-XTR-71723 https://reactome.org/PathwayBrowser/#/R-XTR-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Xenopus tropicalis 15377 R-XTR-71732 https://reactome.org/PathwayBrowser/#/R-XTR-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Xenopus tropicalis 15377 R-XTR-71825 https://reactome.org/PathwayBrowser/#/R-XTR-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Xenopus tropicalis 15377 R-XTR-73571 https://reactome.org/PathwayBrowser/#/R-XTR-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Xenopus tropicalis 15377 R-XTR-73577 https://reactome.org/PathwayBrowser/#/R-XTR-73577 CAD hexamer transforms L-Gln to CAP IEA Xenopus tropicalis 15377 R-XTR-73596 https://reactome.org/PathwayBrowser/#/R-XTR-73596 dCMP + H2O => dUMP + NH4+ IEA Xenopus tropicalis 15377 R-XTR-73608 https://reactome.org/PathwayBrowser/#/R-XTR-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Xenopus tropicalis 15377 R-XTR-73666 https://reactome.org/PathwayBrowser/#/R-XTR-73666 dUTP + H2O => dUMP + pyrophosphate IEA Xenopus tropicalis 15377 R-XTR-73792 https://reactome.org/PathwayBrowser/#/R-XTR-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Xenopus tropicalis 15377 R-XTR-73794 https://reactome.org/PathwayBrowser/#/R-XTR-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Xenopus tropicalis 15377 R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 15377 R-XTR-73815 https://reactome.org/PathwayBrowser/#/R-XTR-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Xenopus tropicalis 15377 R-XTR-74059 https://reactome.org/PathwayBrowser/#/R-XTR-74059 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 15377 R-XTR-74241 https://reactome.org/PathwayBrowser/#/R-XTR-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Xenopus tropicalis 15377 R-XTR-74247 https://reactome.org/PathwayBrowser/#/R-XTR-74247 XDH oxidizes hypoxanthine to form xanthine IEA Xenopus tropicalis 15377 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 15377 R-XTR-74255 https://reactome.org/PathwayBrowser/#/R-XTR-74255 Guanine + H2O => Xanthine + NH4+ IEA Xenopus tropicalis 15377 R-XTR-74258 https://reactome.org/PathwayBrowser/#/R-XTR-74258 XDH oxidizes xanthine to form urate IEA Xenopus tropicalis 15377 R-XTR-74733 https://reactome.org/PathwayBrowser/#/R-XTR-74733 Insulin receptor de-phosphorylation IEA Xenopus tropicalis 15377 R-XTR-75872 https://reactome.org/PathwayBrowser/#/R-XTR-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Xenopus tropicalis 15377 R-XTR-75899 https://reactome.org/PathwayBrowser/#/R-XTR-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Xenopus tropicalis 15377 R-XTR-76031 https://reactome.org/PathwayBrowser/#/R-XTR-76031 2 H2O2 => O2 + 2 H2O IEA Xenopus tropicalis 15377 R-XTR-76354 https://reactome.org/PathwayBrowser/#/R-XTR-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Xenopus tropicalis 15377 R-XTR-76397 https://reactome.org/PathwayBrowser/#/R-XTR-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Xenopus tropicalis 15377 R-XTR-76416 https://reactome.org/PathwayBrowser/#/R-XTR-76416 Benzene is hydroxylated to phenol IEA Xenopus tropicalis 15377 R-XTR-76453 https://reactome.org/PathwayBrowser/#/R-XTR-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Xenopus tropicalis 15377 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 15377 R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 15377 R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 15377 R-XTR-76590 https://reactome.org/PathwayBrowser/#/R-XTR-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Xenopus tropicalis 15377 R-XTR-77256 https://reactome.org/PathwayBrowser/#/R-XTR-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-77277 https://reactome.org/PathwayBrowser/#/R-XTR-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-77301 https://reactome.org/PathwayBrowser/#/R-XTR-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-77314 https://reactome.org/PathwayBrowser/#/R-XTR-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-77325 https://reactome.org/PathwayBrowser/#/R-XTR-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-77333 https://reactome.org/PathwayBrowser/#/R-XTR-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-77344 https://reactome.org/PathwayBrowser/#/R-XTR-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Xenopus tropicalis 15377 R-XTR-77615 https://reactome.org/PathwayBrowser/#/R-XTR-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Xenopus tropicalis 15377 R-XTR-8848053 https://reactome.org/PathwayBrowser/#/R-XTR-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Xenopus tropicalis 15377 R-XTR-8848215 https://reactome.org/PathwayBrowser/#/R-XTR-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Xenopus tropicalis 15377 R-XTR-8848338 https://reactome.org/PathwayBrowser/#/R-XTR-8848338 PNPLA4 hydrolyzes TAG IEA Xenopus tropicalis 15377 R-XTR-8848339 https://reactome.org/PathwayBrowser/#/R-XTR-8848339 PNPLA5 hydrolyzes TAG IEA Xenopus tropicalis 15377 R-XTR-8848355 https://reactome.org/PathwayBrowser/#/R-XTR-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Xenopus tropicalis 15377 R-XTR-8848484 https://reactome.org/PathwayBrowser/#/R-XTR-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Xenopus tropicalis 15377 R-XTR-8849435 https://reactome.org/PathwayBrowser/#/R-XTR-8849435 PTPN1 dephosphorylates PTK6 IEA Xenopus tropicalis 15377 R-XTR-8849969 https://reactome.org/PathwayBrowser/#/R-XTR-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Xenopus tropicalis 15377 R-XTR-8850594 https://reactome.org/PathwayBrowser/#/R-XTR-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Xenopus tropicalis 15377 R-XTR-8850846 https://reactome.org/PathwayBrowser/#/R-XTR-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-XTR-8850854 https://reactome.org/PathwayBrowser/#/R-XTR-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15377 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-XTR-8851110 https://reactome.org/PathwayBrowser/#/R-XTR-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-XTR-8851129 https://reactome.org/PathwayBrowser/#/R-XTR-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15377 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15377 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15377 R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15377 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 15377 R-XTR-8853686 https://reactome.org/PathwayBrowser/#/R-XTR-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Xenopus tropicalis 15377 R-XTR-8854173 https://reactome.org/PathwayBrowser/#/R-XTR-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Xenopus tropicalis 15377 R-XTR-8854255 https://reactome.org/PathwayBrowser/#/R-XTR-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 15377 R-XTR-8854329 https://reactome.org/PathwayBrowser/#/R-XTR-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 15377 R-XTR-8854612 https://reactome.org/PathwayBrowser/#/R-XTR-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Xenopus tropicalis 15377 R-XTR-8856951 https://reactome.org/PathwayBrowser/#/R-XTR-8856951 PP2A demethylation by PPME1 IEA Xenopus tropicalis 15377 R-XTR-8862184 https://reactome.org/PathwayBrowser/#/R-XTR-8862184 USP48 cleaves polyubiquitin IEA Xenopus tropicalis 15377 R-XTR-8862320 https://reactome.org/PathwayBrowser/#/R-XTR-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Xenopus tropicalis 15377 R-XTR-8864029 https://reactome.org/PathwayBrowser/#/R-XTR-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Xenopus tropicalis 15377 R-XTR-8864036 https://reactome.org/PathwayBrowser/#/R-XTR-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Xenopus tropicalis 15377 R-XTR-8864125 https://reactome.org/PathwayBrowser/#/R-XTR-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Xenopus tropicalis 15377 R-XTR-8866405 https://reactome.org/PathwayBrowser/#/R-XTR-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 15377 R-XTR-8866542 https://reactome.org/PathwayBrowser/#/R-XTR-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Xenopus tropicalis 15377 R-XTR-8866601 https://reactome.org/PathwayBrowser/#/R-XTR-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Xenopus tropicalis 15377 R-XTR-8867344 https://reactome.org/PathwayBrowser/#/R-XTR-8867344 OMA1 hydrolyses OPA1 IEA Xenopus tropicalis 15377 R-XTR-8867658 https://reactome.org/PathwayBrowser/#/R-XTR-8867658 PTPN3 dephosphorylates MAPK12 IEA Xenopus tropicalis 15377 R-XTR-8869206 https://reactome.org/PathwayBrowser/#/R-XTR-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Xenopus tropicalis 15377 R-XTR-8869456 https://reactome.org/PathwayBrowser/#/R-XTR-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Xenopus tropicalis 15377 R-XTR-8869506 https://reactome.org/PathwayBrowser/#/R-XTR-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Xenopus tropicalis 15377 R-XTR-8870346 https://reactome.org/PathwayBrowser/#/R-XTR-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Xenopus tropicalis 15377 R-XTR-8874435 https://reactome.org/PathwayBrowser/#/R-XTR-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Xenopus tropicalis 15377 R-XTR-8878581 https://reactome.org/PathwayBrowser/#/R-XTR-8878581 TYRP1 oxidises DHICA to IQCA IEA Xenopus tropicalis 15377 R-XTR-8878654 https://reactome.org/PathwayBrowser/#/R-XTR-8878654 ACP6 hydrolyses MYS-LPA IEA Xenopus tropicalis 15377 R-XTR-8878787 https://reactome.org/PathwayBrowser/#/R-XTR-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Xenopus tropicalis 15377 R-XTR-888548 https://reactome.org/PathwayBrowser/#/R-XTR-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Xenopus tropicalis 15377 R-XTR-8932633 https://reactome.org/PathwayBrowser/#/R-XTR-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Xenopus tropicalis 15377 R-XTR-8936442 https://reactome.org/PathwayBrowser/#/R-XTR-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Xenopus tropicalis 15377 R-XTR-8937767 https://reactome.org/PathwayBrowser/#/R-XTR-8937767 PTPN11 dephosphorylates RUNX1 IEA Xenopus tropicalis 15377 R-XTR-8938076 https://reactome.org/PathwayBrowser/#/R-XTR-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Xenopus tropicalis 15377 R-XTR-8940070 https://reactome.org/PathwayBrowser/#/R-XTR-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Xenopus tropicalis 15377 R-XTR-8940074 https://reactome.org/PathwayBrowser/#/R-XTR-8940074 NT5E:Zn2+ hydrolyses NMN IEA Xenopus tropicalis 15377 R-XTR-8952137 https://reactome.org/PathwayBrowser/#/R-XTR-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Xenopus tropicalis 15377 R-XTR-8952251 https://reactome.org/PathwayBrowser/#/R-XTR-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Xenopus tropicalis 15377 R-XTR-8952903 https://reactome.org/PathwayBrowser/#/R-XTR-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Xenopus tropicalis 15377 R-XTR-8953499 https://reactome.org/PathwayBrowser/#/R-XTR-8953499 IMPAD1 hydrolyses PAP to AMP IEA Xenopus tropicalis 15377 R-XTR-8954398 https://reactome.org/PathwayBrowser/#/R-XTR-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Xenopus tropicalis 15377 R-XTR-8955817 https://reactome.org/PathwayBrowser/#/R-XTR-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Xenopus tropicalis 15377 R-XTR-8980228 https://reactome.org/PathwayBrowser/#/R-XTR-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Xenopus tropicalis 15377 R-XTR-8981637 https://reactome.org/PathwayBrowser/#/R-XTR-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Xenopus tropicalis 15377 R-XTR-8985594 https://reactome.org/PathwayBrowser/#/R-XTR-8985594 MYO9B inactivates RHOA IEA Xenopus tropicalis 15377 R-XTR-9013022 https://reactome.org/PathwayBrowser/#/R-XTR-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Xenopus tropicalis 15377 R-XTR-9013144 https://reactome.org/PathwayBrowser/#/R-XTR-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Xenopus tropicalis 15377 R-XTR-9013161 https://reactome.org/PathwayBrowser/#/R-XTR-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Xenopus tropicalis 15377 R-XTR-9013437 https://reactome.org/PathwayBrowser/#/R-XTR-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Xenopus tropicalis 15377 R-XTR-9014295 https://reactome.org/PathwayBrowser/#/R-XTR-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Xenopus tropicalis 15377 R-XTR-9014434 https://reactome.org/PathwayBrowser/#/R-XTR-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Xenopus tropicalis 15377 R-XTR-9014627 https://reactome.org/PathwayBrowser/#/R-XTR-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Xenopus tropicalis 15377 R-XTR-9014741 https://reactome.org/PathwayBrowser/#/R-XTR-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Xenopus tropicalis 15377 R-XTR-9017488 https://reactome.org/PathwayBrowser/#/R-XTR-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Xenopus tropicalis 15377 R-XTR-9018745 https://reactome.org/PathwayBrowser/#/R-XTR-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Xenopus tropicalis 15377 R-XTR-9018806 https://reactome.org/PathwayBrowser/#/R-XTR-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Xenopus tropicalis 15377 R-XTR-9018826 https://reactome.org/PathwayBrowser/#/R-XTR-9018826 RHOT2 hydrolyzes GTP IEA Xenopus tropicalis 15377 R-XTR-9018862 https://reactome.org/PathwayBrowser/#/R-XTR-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Xenopus tropicalis 15377 R-XTR-9018877 https://reactome.org/PathwayBrowser/#/R-XTR-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Xenopus tropicalis 15377 R-XTR-9020252 https://reactome.org/PathwayBrowser/#/R-XTR-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Xenopus tropicalis 15377 R-XTR-9020253 https://reactome.org/PathwayBrowser/#/R-XTR-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Xenopus tropicalis 15377 R-XTR-9020257 https://reactome.org/PathwayBrowser/#/R-XTR-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Xenopus tropicalis 15377 R-XTR-9020258 https://reactome.org/PathwayBrowser/#/R-XTR-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Xenopus tropicalis 15377 R-XTR-9020270 https://reactome.org/PathwayBrowser/#/R-XTR-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Xenopus tropicalis 15377 R-XTR-9024890 https://reactome.org/PathwayBrowser/#/R-XTR-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Xenopus tropicalis 15377 R-XTR-9027043 https://reactome.org/PathwayBrowser/#/R-XTR-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Xenopus tropicalis 15377 R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 15377 R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 15377 R-XTR-9033491 https://reactome.org/PathwayBrowser/#/R-XTR-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Xenopus tropicalis 15377 R-XTR-9034539 https://reactome.org/PathwayBrowser/#/R-XTR-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Xenopus tropicalis 15377 R-XTR-917841 https://reactome.org/PathwayBrowser/#/R-XTR-917841 Acidification of Tf:TfR1 containing endosome IEA Xenopus tropicalis 15377 R-XTR-917891 https://reactome.org/PathwayBrowser/#/R-XTR-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Xenopus tropicalis 15377 R-XTR-917933 https://reactome.org/PathwayBrowser/#/R-XTR-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Xenopus tropicalis 15377 R-XTR-917979 https://reactome.org/PathwayBrowser/#/R-XTR-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-XTR-936802 https://reactome.org/PathwayBrowser/#/R-XTR-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Xenopus tropicalis 15377 R-XTR-936883 https://reactome.org/PathwayBrowser/#/R-XTR-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Xenopus tropicalis 15377 R-XTR-936895 https://reactome.org/PathwayBrowser/#/R-XTR-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Xenopus tropicalis 15377 R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 15377 R-XTR-937311 https://reactome.org/PathwayBrowser/#/R-XTR-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 15377 R-XTR-939763 https://reactome.org/PathwayBrowser/#/R-XTR-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-947535 https://reactome.org/PathwayBrowser/#/R-XTR-947535 Cyclisation of GTP to precursor Z IEA Xenopus tropicalis 15377 R-XTR-947591 https://reactome.org/PathwayBrowser/#/R-XTR-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Xenopus tropicalis 15377 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 15377 R-XTR-9620103 https://reactome.org/PathwayBrowser/#/R-XTR-9620103 ALDH2 transforms GTN to NO IEA Xenopus tropicalis 15377 R-XTR-9624893 https://reactome.org/PathwayBrowser/#/R-XTR-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Xenopus tropicalis 15377 R-XTR-9638046 https://reactome.org/PathwayBrowser/#/R-XTR-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 15377 R-XTR-9638075 https://reactome.org/PathwayBrowser/#/R-XTR-9638075 HEXB cleaves the terminal GalNAc from DS IEA Xenopus tropicalis 15377 R-XTR-9638076 https://reactome.org/PathwayBrowser/#/R-XTR-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Xenopus tropicalis 15377 R-XTR-9638078 https://reactome.org/PathwayBrowser/#/R-XTR-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Xenopus tropicalis 15377 R-XTR-9638120 https://reactome.org/PathwayBrowser/#/R-XTR-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 15377 R-XTR-9644869 https://reactome.org/PathwayBrowser/#/R-XTR-9644869 p-S54-PDE4B hydrolyses cAMP IEA Xenopus tropicalis 15377 R-XTR-965067 https://reactome.org/PathwayBrowser/#/R-XTR-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Xenopus tropicalis 15377 R-XTR-965079 https://reactome.org/PathwayBrowser/#/R-XTR-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Xenopus tropicalis 15377 R-XTR-9656891 https://reactome.org/PathwayBrowser/#/R-XTR-9656891 OPN1SW binds 11cRAL IEA Xenopus tropicalis 15377 R-XTR-9656893 https://reactome.org/PathwayBrowser/#/R-XTR-9656893 OPN1MW binds 11cRAL IEA Xenopus tropicalis 15377 R-XTR-9661417 https://reactome.org/PathwayBrowser/#/R-XTR-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-XTR-9668419 https://reactome.org/PathwayBrowser/#/R-XTR-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Xenopus tropicalis 15377 R-XTR-9673053 https://reactome.org/PathwayBrowser/#/R-XTR-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Xenopus tropicalis 15377 R-XTR-9673054 https://reactome.org/PathwayBrowser/#/R-XTR-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Xenopus tropicalis 15377 R-XTR-9686524 https://reactome.org/PathwayBrowser/#/R-XTR-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Xenopus tropicalis 15377 R-XTR-9693282 https://reactome.org/PathwayBrowser/#/R-XTR-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Xenopus tropicalis 15377 R-XTR-9701565 https://reactome.org/PathwayBrowser/#/R-XTR-9701565 HDACs deacetylate p-STAT3 dimers IEA Xenopus tropicalis 15377 R-XTR-9705507 https://reactome.org/PathwayBrowser/#/R-XTR-9705507 PDE3B hydrolyses cAMP to AMP IEA Xenopus tropicalis 15377 R-XTR-9708261 https://reactome.org/PathwayBrowser/#/R-XTR-9708261 PDE4A hydrolyses cAMP to AMP IEA Xenopus tropicalis 15377 R-XTR-9709360 https://reactome.org/PathwayBrowser/#/R-XTR-9709360 H2O2 reduces MetHb IEA Xenopus tropicalis 15377 R-XTR-9727198 https://reactome.org/PathwayBrowser/#/R-XTR-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 15377 R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 15377 R-XTR-9727349 https://reactome.org/PathwayBrowser/#/R-XTR-9727349 XDH dehydrogenates xanthine to form urate IEA Xenopus tropicalis 15377 R-XTR-9727567 https://reactome.org/PathwayBrowser/#/R-XTR-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Xenopus tropicalis 15377 R-XTR-9731228 https://reactome.org/PathwayBrowser/#/R-XTR-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Xenopus tropicalis 15377 R-XTR-9731590 https://reactome.org/PathwayBrowser/#/R-XTR-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Xenopus tropicalis 15377 R-XTR-9731613 https://reactome.org/PathwayBrowser/#/R-XTR-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Xenopus tropicalis 15377 R-XTR-9731632 https://reactome.org/PathwayBrowser/#/R-XTR-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Xenopus tropicalis 15377 R-XTR-9731661 https://reactome.org/PathwayBrowser/#/R-XTR-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Xenopus tropicalis 15377 R-XTR-9748945 https://reactome.org/PathwayBrowser/#/R-XTR-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Xenopus tropicalis 15377 R-XTR-9748957 https://reactome.org/PathwayBrowser/#/R-XTR-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Xenopus tropicalis 15377 R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 15377 R-XTR-9749609 https://reactome.org/PathwayBrowser/#/R-XTR-9749609 BCHE hydrolyzes ASA- IEA Xenopus tropicalis 15377 R-XTR-9749792 https://reactome.org/PathwayBrowser/#/R-XTR-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Xenopus tropicalis 15377 R-XTR-9749986 https://reactome.org/PathwayBrowser/#/R-XTR-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Xenopus tropicalis 15377 R-XTR-9750016 https://reactome.org/PathwayBrowser/#/R-XTR-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Xenopus tropicalis 15377 R-XTR-9750555 https://reactome.org/PathwayBrowser/#/R-XTR-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Xenopus tropicalis 15377 R-XTR-9750617 https://reactome.org/PathwayBrowser/#/R-XTR-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-XTR-9750656 https://reactome.org/PathwayBrowser/#/R-XTR-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Xenopus tropicalis 15377 R-XTR-9750942 https://reactome.org/PathwayBrowser/#/R-XTR-9750942 USP14 deubiquitinates NLRC5 IEA Xenopus tropicalis 15377 R-XTR-9753278 https://reactome.org/PathwayBrowser/#/R-XTR-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 15377 R-XTR-9753280 https://reactome.org/PathwayBrowser/#/R-XTR-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Xenopus tropicalis 15377 R-XTR-9753283 https://reactome.org/PathwayBrowser/#/R-XTR-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 15377 R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-XTR-9753285 https://reactome.org/PathwayBrowser/#/R-XTR-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Xenopus tropicalis 15377 R-XTR-9753632 https://reactome.org/PathwayBrowser/#/R-XTR-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Xenopus tropicalis 15377 R-XTR-9753944 https://reactome.org/PathwayBrowser/#/R-XTR-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Xenopus tropicalis 15377 R-XTR-9754964 https://reactome.org/PathwayBrowser/#/R-XTR-9754964 ADA deamidates RBV IEA Xenopus tropicalis 15377 R-XTR-9755030 https://reactome.org/PathwayBrowser/#/R-XTR-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Xenopus tropicalis 15377 R-XTR-9755078 https://reactome.org/PathwayBrowser/#/R-XTR-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Xenopus tropicalis 15377 R-XTR-975593 https://reactome.org/PathwayBrowser/#/R-XTR-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Xenopus tropicalis 15377 R-XTR-9756138 https://reactome.org/PathwayBrowser/#/R-XTR-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Xenopus tropicalis 15377 R-XTR-9756162 https://reactome.org/PathwayBrowser/#/R-XTR-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Xenopus tropicalis 15377 R-XTR-9756169 https://reactome.org/PathwayBrowser/#/R-XTR-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Xenopus tropicalis 15377 R-XTR-9756177 https://reactome.org/PathwayBrowser/#/R-XTR-9756177 PON1,3 hydrolyse ATVL to ATV IEA Xenopus tropicalis 15377 R-XTR-9756180 https://reactome.org/PathwayBrowser/#/R-XTR-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Xenopus tropicalis 15377 R-XTR-9758674 https://reactome.org/PathwayBrowser/#/R-XTR-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Xenopus tropicalis 15377 R-XTR-977324 https://reactome.org/PathwayBrowser/#/R-XTR-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Xenopus tropicalis 15377 R-XTR-9794120 https://reactome.org/PathwayBrowser/#/R-XTR-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Xenopus tropicalis 15377 R-XTR-9794572 https://reactome.org/PathwayBrowser/#/R-XTR-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Xenopus tropicalis 15377 R-XTR-9838289 https://reactome.org/PathwayBrowser/#/R-XTR-9838289 CLPXP degrades mitochondrial matrix proteins IEA Xenopus tropicalis 15377 R-XTR-9839059 https://reactome.org/PathwayBrowser/#/R-XTR-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Xenopus tropicalis 15377 R-XTR-9839105 https://reactome.org/PathwayBrowser/#/R-XTR-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Xenopus tropicalis 15377 R-XTR-9839113 https://reactome.org/PathwayBrowser/#/R-XTR-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Xenopus tropicalis 15377 R-XTR-9840408 https://reactome.org/PathwayBrowser/#/R-XTR-9840408 OMA1 cleaves DELE1 IEA Xenopus tropicalis 15377 R-XTR-9840795 https://reactome.org/PathwayBrowser/#/R-XTR-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Xenopus tropicalis 15377 R-XTR-9840833 https://reactome.org/PathwayBrowser/#/R-XTR-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Xenopus tropicalis 15377 R-XTR-9840949 https://reactome.org/PathwayBrowser/#/R-XTR-9840949 ARSA removes sulfate from SM3 IEA Xenopus tropicalis 15377 R-XTR-9843721 https://reactome.org/PathwayBrowser/#/R-XTR-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Xenopus tropicalis 15377 R-XTR-9853385 https://reactome.org/PathwayBrowser/#/R-XTR-9853385 PPP1CC dephosphorylates PLK1 IEA Xenopus tropicalis 15377 R-XTR-9861626 https://reactome.org/PathwayBrowser/#/R-XTR-9861626 SIRT4 cleaves lipoyl from DLAT IEA Xenopus tropicalis 15377 R-XTR-997309 https://reactome.org/PathwayBrowser/#/R-XTR-997309 Dephosphorylation of STAT1 by SHP2 IEA Xenopus tropicalis 15377 R-XTR-997311 https://reactome.org/PathwayBrowser/#/R-XTR-997311 Dephosphorylation of TYK2 by PTP1B IEA Xenopus tropicalis 15378 R-AMA-1614571 https://reactome.org/PathwayBrowser/#/R-AMA-1614571 Sqr oxidizes sulfide to bound persulfide TAS Arenicola marina 15378 R-BTA-109343 https://reactome.org/PathwayBrowser/#/R-BTA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Bos taurus 15378 R-BTA-111524 https://reactome.org/PathwayBrowser/#/R-BTA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Bos taurus 15378 R-BTA-1222376 https://reactome.org/PathwayBrowser/#/R-BTA-1222376 NOX2 generates superoxide from oxygen IEA Bos taurus 15378 R-BTA-1222516 https://reactome.org/PathwayBrowser/#/R-BTA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Bos taurus 15378 R-BTA-1236967 https://reactome.org/PathwayBrowser/#/R-BTA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Bos taurus 15378 R-BTA-1237045 https://reactome.org/PathwayBrowser/#/R-BTA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Bos taurus 15378 R-BTA-1237047 https://reactome.org/PathwayBrowser/#/R-BTA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Bos taurus 15378 R-BTA-1237059 https://reactome.org/PathwayBrowser/#/R-BTA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Bos taurus 15378 R-BTA-1237081 https://reactome.org/PathwayBrowser/#/R-BTA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Bos taurus 15378 R-BTA-1237129 https://reactome.org/PathwayBrowser/#/R-BTA-1237129 Acireductone is created IEA Bos taurus 15378 R-BTA-1237325 https://reactome.org/PathwayBrowser/#/R-BTA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Bos taurus 15378 R-BTA-1247668 https://reactome.org/PathwayBrowser/#/R-BTA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Bos taurus 15378 R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 15378 R-BTA-140359 https://reactome.org/PathwayBrowser/#/R-BTA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Bos taurus 15378 R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 15378 R-BTA-1475017 https://reactome.org/PathwayBrowser/#/R-BTA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Bos taurus 15378 R-BTA-1475022 https://reactome.org/PathwayBrowser/#/R-BTA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Bos taurus 15378 R-BTA-1475025 https://reactome.org/PathwayBrowser/#/R-BTA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Bos taurus 15378 R-BTA-1475026 https://reactome.org/PathwayBrowser/#/R-BTA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Bos taurus 15378 R-BTA-1475028 https://reactome.org/PathwayBrowser/#/R-BTA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Bos taurus 15378 R-BTA-1475032 https://reactome.org/PathwayBrowser/#/R-BTA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Bos taurus 15378 R-BTA-1475435 https://reactome.org/PathwayBrowser/#/R-BTA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Bos taurus 15378 R-BTA-1475436 https://reactome.org/PathwayBrowser/#/R-BTA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Bos taurus 15378 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 15378 R-BTA-1497869 https://reactome.org/PathwayBrowser/#/R-BTA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Bos taurus 15378 R-BTA-1562626 https://reactome.org/PathwayBrowser/#/R-BTA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Bos taurus 15378 R-BTA-156526 https://reactome.org/PathwayBrowser/#/R-BTA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Bos taurus 15378 R-BTA-158609 https://reactome.org/PathwayBrowser/#/R-BTA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Bos taurus 15378 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 15378 R-BTA-1605797 https://reactome.org/PathwayBrowser/#/R-BTA-1605797 SMPD1 hydrolyzes SPHM IEA Bos taurus 15378 R-BTA-1606273 https://reactome.org/PathwayBrowser/#/R-BTA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Bos taurus 15378 R-BTA-1606288 https://reactome.org/PathwayBrowser/#/R-BTA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Bos taurus 15378 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 15378 R-BTA-1614362 https://reactome.org/PathwayBrowser/#/R-BTA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Bos taurus 15378 R-BTA-1614605 https://reactome.org/PathwayBrowser/#/R-BTA-1614605 Persulfide sulfur is dioxygenated IEA Bos taurus 15378 R-BTA-162730 https://reactome.org/PathwayBrowser/#/R-BTA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Bos taurus 15378 R-BTA-163120 https://reactome.org/PathwayBrowser/#/R-BTA-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Bos taurus 15378 R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 15378 R-BTA-163217 https://reactome.org/PathwayBrowser/#/R-BTA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Bos taurus 15378 R-BTA-1638104 https://reactome.org/PathwayBrowser/#/R-BTA-1638104 UGCG transfers glucose to ceramide IEA Bos taurus 15378 R-BTA-1638845 https://reactome.org/PathwayBrowser/#/R-BTA-1638845 CERK phosphorylates CERA to form C1P IEA Bos taurus 15378 R-BTA-1640164 https://reactome.org/PathwayBrowser/#/R-BTA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Bos taurus 15378 R-BTA-164651 https://reactome.org/PathwayBrowser/#/R-BTA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Bos taurus 15378 R-BTA-164834 https://reactome.org/PathwayBrowser/#/R-BTA-164834 Enzyme-bound ATP is released IEA Bos taurus 15378 R-BTA-1655453 https://reactome.org/PathwayBrowser/#/R-BTA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Bos taurus 15378 R-BTA-1655879 https://reactome.org/PathwayBrowser/#/R-BTA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Bos taurus 15378 R-BTA-1678920 https://reactome.org/PathwayBrowser/#/R-BTA-1678920 TLR processing at low pH IEA Bos taurus 15378 R-BTA-170026 https://reactome.org/PathwayBrowser/#/R-BTA-170026 Protons are translocated from the intermembrane space to the matrix IEA Bos taurus 15378 R-BTA-173597 https://reactome.org/PathwayBrowser/#/R-BTA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Bos taurus 15378 R-BTA-174389 https://reactome.org/PathwayBrowser/#/R-BTA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Bos taurus 15378 R-BTA-174392 https://reactome.org/PathwayBrowser/#/R-BTA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Bos taurus 15378 R-BTA-174438 https://reactome.org/PathwayBrowser/#/R-BTA-174438 Formation of the Flap Intermediate on the C-strand IEA Bos taurus 15378 R-BTA-189421 https://reactome.org/PathwayBrowser/#/R-BTA-189421 CPO transforms COPRO3 to PPGEN9 IEA Bos taurus 15378 R-BTA-189425 https://reactome.org/PathwayBrowser/#/R-BTA-189425 UROD decarboxylates URO3 to COPRO3 IEA Bos taurus 15378 R-BTA-189439 https://reactome.org/PathwayBrowser/#/R-BTA-189439 ALAD condenses 2 dALAs to form PBG IEA Bos taurus 15378 R-BTA-189442 https://reactome.org/PathwayBrowser/#/R-BTA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Bos taurus 15378 R-BTA-189465 https://reactome.org/PathwayBrowser/#/R-BTA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Bos taurus 15378 R-BTA-190182 https://reactome.org/PathwayBrowser/#/R-BTA-190182 UROD decarboxylates URO1 to COPRO1 IEA Bos taurus 15378 R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 15378 R-BTA-191323 https://reactome.org/PathwayBrowser/#/R-BTA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Bos taurus 15378 R-BTA-191352 https://reactome.org/PathwayBrowser/#/R-BTA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Bos taurus 15378 R-BTA-191402 https://reactome.org/PathwayBrowser/#/R-BTA-191402 Reduction of presqualene diphosphate to form squalene IEA Bos taurus 15378 R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 15378 R-BTA-191999 https://reactome.org/PathwayBrowser/#/R-BTA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Bos taurus 15378 R-BTA-192033 https://reactome.org/PathwayBrowser/#/R-BTA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Bos taurus 15378 R-BTA-192036 https://reactome.org/PathwayBrowser/#/R-BTA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Bos taurus 15378 R-BTA-192042 https://reactome.org/PathwayBrowser/#/R-BTA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 15378 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 15378 R-BTA-192054 https://reactome.org/PathwayBrowser/#/R-BTA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Bos taurus 15378 R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 15378 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 15378 R-BTA-192067 https://reactome.org/PathwayBrowser/#/R-BTA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Bos taurus 15378 R-BTA-192097 https://reactome.org/PathwayBrowser/#/R-BTA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Bos taurus 15378 R-BTA-192123 https://reactome.org/PathwayBrowser/#/R-BTA-192123 CYP27A1 27-hydroxylates CHOL IEA Bos taurus 15378 R-BTA-192160 https://reactome.org/PathwayBrowser/#/R-BTA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Bos taurus 15378 R-BTA-192178 https://reactome.org/PathwayBrowser/#/R-BTA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Bos taurus 15378 R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 15378 R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 15378 R-BTA-193064 https://reactome.org/PathwayBrowser/#/R-BTA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Bos taurus 15378 R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 15378 R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 15378 R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 15378 R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 15378 R-BTA-193073 https://reactome.org/PathwayBrowser/#/R-BTA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Bos taurus 15378 R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 15378 R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 15378 R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 15378 R-BTA-193393 https://reactome.org/PathwayBrowser/#/R-BTA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Bos taurus 15378 R-BTA-193455 https://reactome.org/PathwayBrowser/#/R-BTA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 15378 R-BTA-193460 https://reactome.org/PathwayBrowser/#/R-BTA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Bos taurus 15378 R-BTA-193497 https://reactome.org/PathwayBrowser/#/R-BTA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Bos taurus 15378 R-BTA-193508 https://reactome.org/PathwayBrowser/#/R-BTA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 15378 R-BTA-193713 https://reactome.org/PathwayBrowser/#/R-BTA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Bos taurus 15378 R-BTA-193719 https://reactome.org/PathwayBrowser/#/R-BTA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 15378 R-BTA-193737 https://reactome.org/PathwayBrowser/#/R-BTA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Bos taurus 15378 R-BTA-193746 https://reactome.org/PathwayBrowser/#/R-BTA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Bos taurus 15378 R-BTA-193755 https://reactome.org/PathwayBrowser/#/R-BTA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Bos taurus 15378 R-BTA-193758 https://reactome.org/PathwayBrowser/#/R-BTA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Bos taurus 15378 R-BTA-193780 https://reactome.org/PathwayBrowser/#/R-BTA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Bos taurus 15378 R-BTA-193781 https://reactome.org/PathwayBrowser/#/R-BTA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Bos taurus 15378 R-BTA-193787 https://reactome.org/PathwayBrowser/#/R-BTA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Bos taurus 15378 R-BTA-193789 https://reactome.org/PathwayBrowser/#/R-BTA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Bos taurus 15378 R-BTA-193792 https://reactome.org/PathwayBrowser/#/R-BTA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Bos taurus 15378 R-BTA-193800 https://reactome.org/PathwayBrowser/#/R-BTA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Bos taurus 15378 R-BTA-193816 https://reactome.org/PathwayBrowser/#/R-BTA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Bos taurus 15378 R-BTA-193821 https://reactome.org/PathwayBrowser/#/R-BTA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Bos taurus 15378 R-BTA-193824 https://reactome.org/PathwayBrowser/#/R-BTA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Bos taurus 15378 R-BTA-193841 https://reactome.org/PathwayBrowser/#/R-BTA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Bos taurus 15378 R-BTA-193964 https://reactome.org/PathwayBrowser/#/R-BTA-193964 CYP21A2 21-hydroxylates PROG IEA Bos taurus 15378 R-BTA-193965 https://reactome.org/PathwayBrowser/#/R-BTA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Bos taurus 15378 R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 15378 R-BTA-193995 https://reactome.org/PathwayBrowser/#/R-BTA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Bos taurus 15378 R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 15378 R-BTA-194017 https://reactome.org/PathwayBrowser/#/R-BTA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Bos taurus 15378 R-BTA-194023 https://reactome.org/PathwayBrowser/#/R-BTA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Bos taurus 15378 R-BTA-194632 https://reactome.org/PathwayBrowser/#/R-BTA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Bos taurus 15378 R-BTA-194641 https://reactome.org/PathwayBrowser/#/R-BTA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15378 R-BTA-194642 https://reactome.org/PathwayBrowser/#/R-BTA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Bos taurus 15378 R-BTA-194669 https://reactome.org/PathwayBrowser/#/R-BTA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15378 R-BTA-194674 https://reactome.org/PathwayBrowser/#/R-BTA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Bos taurus 15378 R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 15378 R-BTA-194689 https://reactome.org/PathwayBrowser/#/R-BTA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15378 R-BTA-194698 https://reactome.org/PathwayBrowser/#/R-BTA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Bos taurus 15378 R-BTA-194718 https://reactome.org/PathwayBrowser/#/R-BTA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Bos taurus 15378 R-BTA-195664 https://reactome.org/PathwayBrowser/#/R-BTA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Bos taurus 15378 R-BTA-196060 https://reactome.org/PathwayBrowser/#/R-BTA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Bos taurus 15378 R-BTA-196350 https://reactome.org/PathwayBrowser/#/R-BTA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Bos taurus 15378 R-BTA-196372 https://reactome.org/PathwayBrowser/#/R-BTA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Bos taurus 15378 R-BTA-196402 https://reactome.org/PathwayBrowser/#/R-BTA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Bos taurus 15378 R-BTA-196417 https://reactome.org/PathwayBrowser/#/R-BTA-196417 Reduction of desmosterol to cholesterol IEA Bos taurus 15378 R-BTA-196753 https://reactome.org/PathwayBrowser/#/R-BTA-196753 2xPPCS ligates PPanK with Cys IEA Bos taurus 15378 R-BTA-196754 https://reactome.org/PathwayBrowser/#/R-BTA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Bos taurus 15378 R-BTA-196773 https://reactome.org/PathwayBrowser/#/R-BTA-196773 COASY phosphorylates DP-CoA IEA Bos taurus 15378 R-BTA-196840 https://reactome.org/PathwayBrowser/#/R-BTA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Bos taurus 15378 R-BTA-196857 https://reactome.org/PathwayBrowser/#/R-BTA-196857 PANK2 phosphorylates PanK IEA Bos taurus 15378 R-BTA-196929 https://reactome.org/PathwayBrowser/#/R-BTA-196929 FLAD1 phosphorylates FMN IEA Bos taurus 15378 R-BTA-196955 https://reactome.org/PathwayBrowser/#/R-BTA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Bos taurus 15378 R-BTA-196964 https://reactome.org/PathwayBrowser/#/R-BTA-196964 RFK:Mg2+ phosphorylates RIB IEA Bos taurus 15378 R-BTA-197186 https://reactome.org/PathwayBrowser/#/R-BTA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Bos taurus 15378 R-BTA-197268 https://reactome.org/PathwayBrowser/#/R-BTA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Bos taurus 15378 R-BTA-197963 https://reactome.org/PathwayBrowser/#/R-BTA-197963 DHFR2 reduces FOLA to DHF IEA Bos taurus 15378 R-BTA-197972 https://reactome.org/PathwayBrowser/#/R-BTA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Bos taurus 15378 R-BTA-198824 https://reactome.org/PathwayBrowser/#/R-BTA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Bos taurus 15378 R-BTA-199203 https://reactome.org/PathwayBrowser/#/R-BTA-199203 PANK1/3 phosphorylate PanK IEA Bos taurus 15378 R-BTA-200644 https://reactome.org/PathwayBrowser/#/R-BTA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Bos taurus 15378 R-BTA-200676 https://reactome.org/PathwayBrowser/#/R-BTA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Bos taurus 15378 R-BTA-200718 https://reactome.org/PathwayBrowser/#/R-BTA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Bos taurus 15378 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 15378 R-BTA-204617 https://reactome.org/PathwayBrowser/#/R-BTA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Bos taurus 15378 R-BTA-204647 https://reactome.org/PathwayBrowser/#/R-BTA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Bos taurus 15378 R-BTA-204662 https://reactome.org/PathwayBrowser/#/R-BTA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Bos taurus 15378 R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 15378 R-BTA-209772 https://reactome.org/PathwayBrowser/#/R-BTA-209772 Thyroxine is deiodinated to triiodothyronine IEA Bos taurus 15378 R-BTA-209821 https://reactome.org/PathwayBrowser/#/R-BTA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Bos taurus 15378 R-BTA-209845 https://reactome.org/PathwayBrowser/#/R-BTA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Bos taurus 15378 R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 15378 R-BTA-209903 https://reactome.org/PathwayBrowser/#/R-BTA-209903 Noradrenaline is converted to adrenaline IEA Bos taurus 15378 R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 15378 R-BTA-210404 https://reactome.org/PathwayBrowser/#/R-BTA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Bos taurus 15378 R-BTA-211873 https://reactome.org/PathwayBrowser/#/R-BTA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Bos taurus 15378 R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 15378 R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 15378 R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 15378 R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 15378 R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 15378 R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 15378 R-BTA-211923 https://reactome.org/PathwayBrowser/#/R-BTA-211923 CYP26C1 4-hydroxylates 9cRA IEA Bos taurus 15378 R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 15378 R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 15378 R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 15378 R-BTA-211950 https://reactome.org/PathwayBrowser/#/R-BTA-211950 CYP24A1 24-hydroxylates CTL IEA Bos taurus 15378 R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 15378 R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 15378 R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 15378 R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 15378 R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 15378 R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 15378 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 15378 R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 15378 R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 15378 R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 15378 R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 15378 R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 15378 R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 15378 R-BTA-2161187 https://reactome.org/PathwayBrowser/#/R-BTA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Bos taurus 15378 R-BTA-2161549 https://reactome.org/PathwayBrowser/#/R-BTA-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Bos taurus 15378 R-BTA-2161614 https://reactome.org/PathwayBrowser/#/R-BTA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Bos taurus 15378 R-BTA-2161651 https://reactome.org/PathwayBrowser/#/R-BTA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Bos taurus 15378 R-BTA-2161745 https://reactome.org/PathwayBrowser/#/R-BTA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Bos taurus 15378 R-BTA-2161779 https://reactome.org/PathwayBrowser/#/R-BTA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Bos taurus 15378 R-BTA-2161792 https://reactome.org/PathwayBrowser/#/R-BTA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Bos taurus 15378 R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Bos taurus 15378 R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 15378 R-BTA-2161890 https://reactome.org/PathwayBrowser/#/R-BTA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Bos taurus 15378 R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Bos taurus 15378 R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 15378 R-BTA-2161951 https://reactome.org/PathwayBrowser/#/R-BTA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Bos taurus 15378 R-BTA-2162078 https://reactome.org/PathwayBrowser/#/R-BTA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Bos taurus 15378 R-BTA-2162186 https://reactome.org/PathwayBrowser/#/R-BTA-2162186 COQ3 methylates DeMQ10H2 IEA Bos taurus 15378 R-BTA-2162188 https://reactome.org/PathwayBrowser/#/R-BTA-2162188 COQ5 methylates MDMQ10H2 IEA Bos taurus 15378 R-BTA-2162193 https://reactome.org/PathwayBrowser/#/R-BTA-2162193 COQ3 methylates DHDB IEA Bos taurus 15378 R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 15378 R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 15378 R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 15378 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 15378 R-BTA-2395512 https://reactome.org/PathwayBrowser/#/R-BTA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Bos taurus 15378 R-BTA-2395517 https://reactome.org/PathwayBrowser/#/R-BTA-2395517 NADPH transfers electrons to FDXR IEA Bos taurus 15378 R-BTA-2395818 https://reactome.org/PathwayBrowser/#/R-BTA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Bos taurus 15378 R-BTA-2395849 https://reactome.org/PathwayBrowser/#/R-BTA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 15378 R-BTA-2395869 https://reactome.org/PathwayBrowser/#/R-BTA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 15378 R-BTA-2395872 https://reactome.org/PathwayBrowser/#/R-BTA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Bos taurus 15378 R-BTA-2395873 https://reactome.org/PathwayBrowser/#/R-BTA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Bos taurus 15378 R-BTA-2395876 https://reactome.org/PathwayBrowser/#/R-BTA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 15378 R-BTA-2395879 https://reactome.org/PathwayBrowser/#/R-BTA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 15378 R-BTA-2395965 https://reactome.org/PathwayBrowser/#/R-BTA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Bos taurus 15378 R-BTA-2408527 https://reactome.org/PathwayBrowser/#/R-BTA-2408527 SeO3(2-) is reduced to H2Se by TXNRD1 TAS Bos taurus 15378 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 15378 R-BTA-2454081 https://reactome.org/PathwayBrowser/#/R-BTA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Bos taurus 15378 R-BTA-2464776 https://reactome.org/PathwayBrowser/#/R-BTA-2464776 Rdh8 reduces atRAL to atROL TAS Bos taurus 15378 R-BTA-2464822 https://reactome.org/PathwayBrowser/#/R-BTA-2464822 RDH12 reduces atRAL to atROL IEA Bos taurus 15378 R-BTA-2465940 https://reactome.org/PathwayBrowser/#/R-BTA-2465940 atRAL is reduced to atROL IEA Bos taurus 15378 R-BTA-2509793 https://reactome.org/PathwayBrowser/#/R-BTA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Bos taurus 15378 R-BTA-2509816 https://reactome.org/PathwayBrowser/#/R-BTA-2509816 NUDT16 hydrolyses IDP to IMP IEA Bos taurus 15378 R-BTA-2509827 https://reactome.org/PathwayBrowser/#/R-BTA-2509827 ITPA hydrolyses ITP to IMP IEA Bos taurus 15378 R-BTA-2509831 https://reactome.org/PathwayBrowser/#/R-BTA-2509831 ITPA hydrolyses XTP to XMP IEA Bos taurus 15378 R-BTA-2509838 https://reactome.org/PathwayBrowser/#/R-BTA-2509838 ITPA hydrolyses dITP to dIMP IEA Bos taurus 15378 R-BTA-2534378 https://reactome.org/PathwayBrowser/#/R-BTA-2534378 Hv1 Mediated H+ Permeability IEA Bos taurus 15378 R-BTA-264615 https://reactome.org/PathwayBrowser/#/R-BTA-264615 Loading of acetylcholine in synaptic vesicles IEA Bos taurus 15378 R-BTA-2671885 https://reactome.org/PathwayBrowser/#/R-BTA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Bos taurus 15378 R-BTA-2730692 https://reactome.org/PathwayBrowser/#/R-BTA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Bos taurus 15378 R-BTA-2730959 https://reactome.org/PathwayBrowser/#/R-BTA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Bos taurus 15378 R-BTA-2855252 https://reactome.org/PathwayBrowser/#/R-BTA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Bos taurus 15378 R-BTA-2872444 https://reactome.org/PathwayBrowser/#/R-BTA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Bos taurus 15378 R-BTA-2889070 https://reactome.org/PathwayBrowser/#/R-BTA-2889070 SLC9B2 exchanges Na+ for H+ IEA Bos taurus 15378 R-BTA-3095889 https://reactome.org/PathwayBrowser/#/R-BTA-3095889 MMACHC dealkylates RCbl IEA Bos taurus 15378 R-BTA-3149518 https://reactome.org/PathwayBrowser/#/R-BTA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Bos taurus 15378 R-BTA-3149519 https://reactome.org/PathwayBrowser/#/R-BTA-3149519 MMACHC decyanates CNCbl IEA Bos taurus 15378 R-BTA-3159253 https://reactome.org/PathwayBrowser/#/R-BTA-3159253 MMAB adenosylates cob(I)alamin IEA Bos taurus 15378 R-BTA-3299680 https://reactome.org/PathwayBrowser/#/R-BTA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Bos taurus 15378 R-BTA-3299682 https://reactome.org/PathwayBrowser/#/R-BTA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Bos taurus 15378 R-BTA-3299691 https://reactome.org/PathwayBrowser/#/R-BTA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Bos taurus 15378 R-BTA-3323050 https://reactome.org/PathwayBrowser/#/R-BTA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Bos taurus 15378 R-BTA-3323079 https://reactome.org/PathwayBrowser/#/R-BTA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 15378 R-BTA-350869 https://reactome.org/PathwayBrowser/#/R-BTA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Bos taurus 15378 R-BTA-350901 https://reactome.org/PathwayBrowser/#/R-BTA-350901 Iodide is organified IEA Bos taurus 15378 R-BTA-352174 https://reactome.org/PathwayBrowser/#/R-BTA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Bos taurus 15378 R-BTA-352182 https://reactome.org/PathwayBrowser/#/R-BTA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Bos taurus 15378 R-BTA-372448 https://reactome.org/PathwayBrowser/#/R-BTA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Bos taurus 15378 R-BTA-373867 https://reactome.org/PathwayBrowser/#/R-BTA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-BTA-373875 https://reactome.org/PathwayBrowser/#/R-BTA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Bos taurus 15378 R-BTA-375405 https://reactome.org/PathwayBrowser/#/R-BTA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Bos taurus 15378 R-BTA-375417 https://reactome.org/PathwayBrowser/#/R-BTA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Bos taurus 15378 R-BTA-3777112 https://reactome.org/PathwayBrowser/#/R-BTA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Bos taurus 15378 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15378 R-BTA-380608 https://reactome.org/PathwayBrowser/#/R-BTA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Bos taurus 15378 R-BTA-389540 https://reactome.org/PathwayBrowser/#/R-BTA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 15378 R-BTA-389550 https://reactome.org/PathwayBrowser/#/R-BTA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 15378 R-BTA-389609 https://reactome.org/PathwayBrowser/#/R-BTA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Bos taurus 15378 R-BTA-389826 https://reactome.org/PathwayBrowser/#/R-BTA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Bos taurus 15378 R-BTA-389995 https://reactome.org/PathwayBrowser/#/R-BTA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Bos taurus 15378 R-BTA-390251 https://reactome.org/PathwayBrowser/#/R-BTA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 15378 R-BTA-390425 https://reactome.org/PathwayBrowser/#/R-BTA-390425 FAR1 reduces PalmCoA to HXOL IEA Bos taurus 15378 R-BTA-390438 https://reactome.org/PathwayBrowser/#/R-BTA-390438 FAR2 reduces PalmCoA to HXOL IEA Bos taurus 15378 R-BTA-418365 https://reactome.org/PathwayBrowser/#/R-BTA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Bos taurus 15378 R-BTA-425577 https://reactome.org/PathwayBrowser/#/R-BTA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Bos taurus 15378 R-BTA-425965 https://reactome.org/PathwayBrowser/#/R-BTA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Bos taurus 15378 R-BTA-425983 https://reactome.org/PathwayBrowser/#/R-BTA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Bos taurus 15378 R-BTA-425994 https://reactome.org/PathwayBrowser/#/R-BTA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Bos taurus 15378 R-BTA-426015 https://reactome.org/PathwayBrowser/#/R-BTA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Bos taurus 15378 R-BTA-426043 https://reactome.org/PathwayBrowser/#/R-BTA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Bos taurus 15378 R-BTA-427555 https://reactome.org/PathwayBrowser/#/R-BTA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Bos taurus 15378 R-BTA-427910 https://reactome.org/PathwayBrowser/#/R-BTA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Bos taurus 15378 R-BTA-427998 https://reactome.org/PathwayBrowser/#/R-BTA-427998 Proton-coupled di- and tri-peptide cotransport IEA Bos taurus 15378 R-BTA-428007 https://reactome.org/PathwayBrowser/#/R-BTA-428007 Proton-coupled histidine and di-peptide cotransport IEA Bos taurus 15378 R-BTA-428015 https://reactome.org/PathwayBrowser/#/R-BTA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Bos taurus 15378 R-BTA-428052 https://reactome.org/PathwayBrowser/#/R-BTA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Bos taurus 15378 R-BTA-428123 https://reactome.org/PathwayBrowser/#/R-BTA-428123 KDSR reduces 3-ketosphingoid IEA Bos taurus 15378 R-BTA-428127 https://reactome.org/PathwayBrowser/#/R-BTA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Bos taurus 15378 R-BTA-428185 https://reactome.org/PathwayBrowser/#/R-BTA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Bos taurus 15378 R-BTA-428259 https://reactome.org/PathwayBrowser/#/R-BTA-428259 DEGS1 dehydrogenates dihydroceramide IEA Bos taurus 15378 R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 15378 R-BTA-428273 https://reactome.org/PathwayBrowser/#/R-BTA-428273 SPHK1 phosphorylates sphingoid IEA Bos taurus 15378 R-BTA-428585 https://reactome.org/PathwayBrowser/#/R-BTA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Bos taurus 15378 R-BTA-428625 https://reactome.org/PathwayBrowser/#/R-BTA-428625 Vesicular inhibitory amino acid transport IEA Bos taurus 15378 R-BTA-429101 https://reactome.org/PathwayBrowser/#/R-BTA-429101 HMIT co-transports myo-inositol with a proton IEA Bos taurus 15378 R-BTA-429157 https://reactome.org/PathwayBrowser/#/R-BTA-429157 ABCC4 accumulation of dense granule contents IEA Bos taurus 15378 R-BTA-429698 https://reactome.org/PathwayBrowser/#/R-BTA-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Bos taurus 15378 R-BTA-429714 https://reactome.org/PathwayBrowser/#/R-BTA-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Bos taurus 15378 R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-BTA-434650 https://reactome.org/PathwayBrowser/#/R-BTA-434650 MATEs mediate extrusion of xenobiotics IEA Bos taurus 15378 R-BTA-435171 https://reactome.org/PathwayBrowser/#/R-BTA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Bos taurus 15378 R-BTA-435349 https://reactome.org/PathwayBrowser/#/R-BTA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-BTA-444393 https://reactome.org/PathwayBrowser/#/R-BTA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Bos taurus 15378 R-BTA-444419 https://reactome.org/PathwayBrowser/#/R-BTA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Bos taurus 15378 R-BTA-444731 https://reactome.org/PathwayBrowser/#/R-BTA-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Bos taurus 15378 R-BTA-446277 https://reactome.org/PathwayBrowser/#/R-BTA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Bos taurus 15378 R-BTA-446278 https://reactome.org/PathwayBrowser/#/R-BTA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Bos taurus 15378 R-BTA-450971 https://reactome.org/PathwayBrowser/#/R-BTA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Bos taurus 15378 R-BTA-469659 https://reactome.org/PathwayBrowser/#/R-BTA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Bos taurus 15378 R-BTA-504054 https://reactome.org/PathwayBrowser/#/R-BTA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Bos taurus 15378 R-BTA-508040 https://reactome.org/PathwayBrowser/#/R-BTA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Bos taurus 15378 R-BTA-508369 https://reactome.org/PathwayBrowser/#/R-BTA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Bos taurus 15378 R-BTA-508473 https://reactome.org/PathwayBrowser/#/R-BTA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Bos taurus 15378 R-BTA-514604 https://reactome.org/PathwayBrowser/#/R-BTA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Bos taurus 15378 R-BTA-5218841 https://reactome.org/PathwayBrowser/#/R-BTA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Bos taurus 15378 R-BTA-5263614 https://reactome.org/PathwayBrowser/#/R-BTA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Bos taurus 15378 R-BTA-5263616 https://reactome.org/PathwayBrowser/#/R-BTA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Bos taurus 15378 R-BTA-5340130 https://reactome.org/PathwayBrowser/#/R-BTA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Bos taurus 15378 R-BTA-5340226 https://reactome.org/PathwayBrowser/#/R-BTA-5340226 CYGB dioxygenates NO IEA Bos taurus 15378 R-BTA-5362518 https://reactome.org/PathwayBrowser/#/R-BTA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Bos taurus 15378 R-BTA-5362522 https://reactome.org/PathwayBrowser/#/R-BTA-5362522 ALDHs oxidise atRAL to atRA IEA Bos taurus 15378 R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 15378 R-BTA-5362564 https://reactome.org/PathwayBrowser/#/R-BTA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Bos taurus 15378 R-BTA-5362721 https://reactome.org/PathwayBrowser/#/R-BTA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Bos taurus 15378 R-BTA-5419165 https://reactome.org/PathwayBrowser/#/R-BTA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Bos taurus 15378 R-BTA-5423637 https://reactome.org/PathwayBrowser/#/R-BTA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Bos taurus 15378 R-BTA-5423647 https://reactome.org/PathwayBrowser/#/R-BTA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Bos taurus 15378 R-BTA-5423664 https://reactome.org/PathwayBrowser/#/R-BTA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Bos taurus 15378 R-BTA-5423672 https://reactome.org/PathwayBrowser/#/R-BTA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Bos taurus 15378 R-BTA-5423678 https://reactome.org/PathwayBrowser/#/R-BTA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Bos taurus 15378 R-BTA-548818 https://reactome.org/PathwayBrowser/#/R-BTA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Bos taurus 15378 R-BTA-548831 https://reactome.org/PathwayBrowser/#/R-BTA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Bos taurus 15378 R-BTA-5602295 https://reactome.org/PathwayBrowser/#/R-BTA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Bos taurus 15378 R-BTA-5615668 https://reactome.org/PathwayBrowser/#/R-BTA-5615668 AKR1C3 reduces atRAL to atROL IEA Bos taurus 15378 R-BTA-5623643 https://reactome.org/PathwayBrowser/#/R-BTA-5623643 RDH13 reduces atRAL to atROL IEA Bos taurus 15378 R-BTA-5652172 https://reactome.org/PathwayBrowser/#/R-BTA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Bos taurus 15378 R-BTA-5652195 https://reactome.org/PathwayBrowser/#/R-BTA-5652195 SORD oxidizes D-sorbitol to Fru IEA Bos taurus 15378 R-BTA-5661240 https://reactome.org/PathwayBrowser/#/R-BTA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Bos taurus 15378 R-BTA-5661256 https://reactome.org/PathwayBrowser/#/R-BTA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Bos taurus 15378 R-BTA-5661290 https://reactome.org/PathwayBrowser/#/R-BTA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Bos taurus 15378 R-BTA-5662471 https://reactome.org/PathwayBrowser/#/R-BTA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Bos taurus 15378 R-BTA-5662662 https://reactome.org/PathwayBrowser/#/R-BTA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Bos taurus 15378 R-BTA-5668629 https://reactome.org/PathwayBrowser/#/R-BTA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Bos taurus 15378 R-BTA-5668718 https://reactome.org/PathwayBrowser/#/R-BTA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 15378 R-BTA-5668731 https://reactome.org/PathwayBrowser/#/R-BTA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 15378 R-BTA-5678327 https://reactome.org/PathwayBrowser/#/R-BTA-5678327 MIOX oxidises Ins to GlcA IEA Bos taurus 15378 R-BTA-5690565 https://reactome.org/PathwayBrowser/#/R-BTA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Bos taurus 15378 R-BTA-5691107 https://reactome.org/PathwayBrowser/#/R-BTA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Bos taurus 15378 R-BTA-5692237 https://reactome.org/PathwayBrowser/#/R-BTA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Bos taurus 15378 R-BTA-5692261 https://reactome.org/PathwayBrowser/#/R-BTA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Bos taurus 15378 R-BTA-5692283 https://reactome.org/PathwayBrowser/#/R-BTA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Bos taurus 15378 R-BTA-5693347 https://reactome.org/PathwayBrowser/#/R-BTA-5693347 CRYM reduces P2C to PPCA IEA Bos taurus 15378 R-BTA-5693390 https://reactome.org/PathwayBrowser/#/R-BTA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Bos taurus 15378 R-BTA-5693681 https://reactome.org/PathwayBrowser/#/R-BTA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Bos taurus 15378 R-BTA-5693691 https://reactome.org/PathwayBrowser/#/R-BTA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Bos taurus 15378 R-BTA-5693761 https://reactome.org/PathwayBrowser/#/R-BTA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Bos taurus 15378 R-BTA-5694018 https://reactome.org/PathwayBrowser/#/R-BTA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Bos taurus 15378 R-BTA-5694462 https://reactome.org/PathwayBrowser/#/R-BTA-5694462 ABHD6,12 hydrolyse 3AG IEA Bos taurus 15378 R-BTA-5696080 https://reactome.org/PathwayBrowser/#/R-BTA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Bos taurus 15378 R-BTA-5696091 https://reactome.org/PathwayBrowser/#/R-BTA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Bos taurus 15378 R-BTA-5696101 https://reactome.org/PathwayBrowser/#/R-BTA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Bos taurus 15378 R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 15378 R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 15378 R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 15378 R-BTA-5696457 https://reactome.org/PathwayBrowser/#/R-BTA-5696457 BDH2 dehydrogenates 3HBA IEA Bos taurus 15378 R-BTA-5696822 https://reactome.org/PathwayBrowser/#/R-BTA-5696822 AKR1B15 reduces EST17b to E1 IEA Bos taurus 15378 R-BTA-5696838 https://reactome.org/PathwayBrowser/#/R-BTA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Bos taurus 15378 R-BTA-597628 https://reactome.org/PathwayBrowser/#/R-BTA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Bos taurus 15378 R-BTA-6783221 https://reactome.org/PathwayBrowser/#/R-BTA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Bos taurus 15378 R-BTA-6783939 https://reactome.org/PathwayBrowser/#/R-BTA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 15378 R-BTA-6783955 https://reactome.org/PathwayBrowser/#/R-BTA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 15378 R-BTA-6784399 https://reactome.org/PathwayBrowser/#/R-BTA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Bos taurus 15378 R-BTA-6785933 https://reactome.org/PathwayBrowser/#/R-BTA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Bos taurus 15378 R-BTA-6786239 https://reactome.org/PathwayBrowser/#/R-BTA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Bos taurus 15378 R-BTA-6786720 https://reactome.org/PathwayBrowser/#/R-BTA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Bos taurus 15378 R-BTA-6787642 https://reactome.org/PathwayBrowser/#/R-BTA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Bos taurus 15378 R-BTA-6788999 https://reactome.org/PathwayBrowser/#/R-BTA-6788999 HV1-mediated H+ transfer IEA Bos taurus 15378 R-BTA-6789031 https://reactome.org/PathwayBrowser/#/R-BTA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 15378 R-BTA-6789092 https://reactome.org/PathwayBrowser/#/R-BTA-6789092 NOX2 generates superoxide anion from oxygen IEA Bos taurus 15378 R-BTA-6789126 https://reactome.org/PathwayBrowser/#/R-BTA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 15378 R-BTA-6793590 https://reactome.org/PathwayBrowser/#/R-BTA-6793590 LIPT2 transfers octanoyl group to GCSH IEA Bos taurus 15378 R-BTA-6793591 https://reactome.org/PathwayBrowser/#/R-BTA-6793591 LIAS synthesizes lipoyl-GCSH IEA Bos taurus 15378 R-BTA-6799495 https://reactome.org/PathwayBrowser/#/R-BTA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Bos taurus 15378 R-BTA-6799722 https://reactome.org/PathwayBrowser/#/R-BTA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Bos taurus 15378 R-BTA-6801342 https://reactome.org/PathwayBrowser/#/R-BTA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Bos taurus 15378 R-BTA-6803771 https://reactome.org/PathwayBrowser/#/R-BTA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Bos taurus 15378 R-BTA-6806647 https://reactome.org/PathwayBrowser/#/R-BTA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 15378 R-BTA-6806831 https://reactome.org/PathwayBrowser/#/R-BTA-6806831 CYB5Rs reduce MetHb to HbA IEA Bos taurus 15378 R-BTA-6806967 https://reactome.org/PathwayBrowser/#/R-BTA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Bos taurus 15378 R-BTA-6807053 https://reactome.org/PathwayBrowser/#/R-BTA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Bos taurus 15378 R-BTA-6807055 https://reactome.org/PathwayBrowser/#/R-BTA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Bos taurus 15378 R-BTA-6807064 https://reactome.org/PathwayBrowser/#/R-BTA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Bos taurus 15378 R-BTA-6807557 https://reactome.org/PathwayBrowser/#/R-BTA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Bos taurus 15378 R-BTA-6808464 https://reactome.org/PathwayBrowser/#/R-BTA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Bos taurus 15378 R-BTA-6808487 https://reactome.org/PathwayBrowser/#/R-BTA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 15378 R-BTA-6808496 https://reactome.org/PathwayBrowser/#/R-BTA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 15378 R-BTA-6809264 https://reactome.org/PathwayBrowser/#/R-BTA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 15378 R-BTA-6809287 https://reactome.org/PathwayBrowser/#/R-BTA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Bos taurus 15378 R-BTA-6809810 https://reactome.org/PathwayBrowser/#/R-BTA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Bos taurus 15378 R-BTA-6810594 https://reactome.org/PathwayBrowser/#/R-BTA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 15378 R-BTA-6813749 https://reactome.org/PathwayBrowser/#/R-BTA-6813749 ALDH1A1 oxidises GA to DGA IEA Bos taurus 15378 R-BTA-6814153 https://reactome.org/PathwayBrowser/#/R-BTA-6814153 ADO oxidises 2AET to HTAU IEA Bos taurus 15378 R-BTA-70333 https://reactome.org/PathwayBrowser/#/R-BTA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Bos taurus 15378 R-BTA-70377 https://reactome.org/PathwayBrowser/#/R-BTA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Bos taurus 15378 R-BTA-70420 https://reactome.org/PathwayBrowser/#/R-BTA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Bos taurus 15378 R-BTA-70449 https://reactome.org/PathwayBrowser/#/R-BTA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Bos taurus 15378 R-BTA-70467 https://reactome.org/PathwayBrowser/#/R-BTA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Bos taurus 15378 R-BTA-70482 https://reactome.org/PathwayBrowser/#/R-BTA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Bos taurus 15378 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 15378 R-BTA-70510 https://reactome.org/PathwayBrowser/#/R-BTA-70510 LDH tetramer oxidises LACT to PYR IEA Bos taurus 15378 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Bos taurus 15378 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Bos taurus 15378 R-BTA-70664 https://reactome.org/PathwayBrowser/#/R-BTA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 15378 R-BTA-70670 https://reactome.org/PathwayBrowser/#/R-BTA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Bos taurus 15378 R-BTA-70679 https://reactome.org/PathwayBrowser/#/R-BTA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Bos taurus 15378 R-BTA-70837 https://reactome.org/PathwayBrowser/#/R-BTA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Bos taurus 15378 R-BTA-70885 https://reactome.org/PathwayBrowser/#/R-BTA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Bos taurus 15378 R-BTA-70893 https://reactome.org/PathwayBrowser/#/R-BTA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Bos taurus 15378 R-BTA-70906 https://reactome.org/PathwayBrowser/#/R-BTA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Bos taurus 15378 R-BTA-70938 https://reactome.org/PathwayBrowser/#/R-BTA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Bos taurus 15378 R-BTA-70940 https://reactome.org/PathwayBrowser/#/R-BTA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Bos taurus 15378 R-BTA-70941 https://reactome.org/PathwayBrowser/#/R-BTA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Bos taurus 15378 R-BTA-70975 https://reactome.org/PathwayBrowser/#/R-BTA-70975 CS acetylates OA to citrate IEA Bos taurus 15378 R-BTA-70979 https://reactome.org/PathwayBrowser/#/R-BTA-70979 MDH2 dimer dehydrogenates MAL IEA Bos taurus 15378 R-BTA-71130 https://reactome.org/PathwayBrowser/#/R-BTA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Bos taurus 15378 R-BTA-71164 https://reactome.org/PathwayBrowser/#/R-BTA-71164 HGD dioxygenates homogentisate IEA Bos taurus 15378 R-BTA-71181 https://reactome.org/PathwayBrowser/#/R-BTA-71181 FAH cleaves 4FAA IEA Bos taurus 15378 R-BTA-71200 https://reactome.org/PathwayBrowser/#/R-BTA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Bos taurus 15378 R-BTA-71260 https://reactome.org/PathwayBrowser/#/R-BTA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Bos taurus 15378 R-BTA-71286 https://reactome.org/PathwayBrowser/#/R-BTA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Bos taurus 15378 R-BTA-71299 https://reactome.org/PathwayBrowser/#/R-BTA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Bos taurus 15378 R-BTA-71401 https://reactome.org/PathwayBrowser/#/R-BTA-71401 OGDH dimer decarboxylates 2-OG IEA Bos taurus 15378 R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 15378 R-BTA-71682 https://reactome.org/PathwayBrowser/#/R-BTA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 15378 R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 15378 R-BTA-71707 https://reactome.org/PathwayBrowser/#/R-BTA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Bos taurus 15378 R-BTA-71723 https://reactome.org/PathwayBrowser/#/R-BTA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Bos taurus 15378 R-BTA-71849 https://reactome.org/PathwayBrowser/#/R-BTA-71849 LDH tetramer reduces PYR to LACT IEA Bos taurus 15378 R-BTA-73564 https://reactome.org/PathwayBrowser/#/R-BTA-73564 UMPS dimer decarboxylates OMP to UMP IEA Bos taurus 15378 R-BTA-73571 https://reactome.org/PathwayBrowser/#/R-BTA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Bos taurus 15378 R-BTA-73573 https://reactome.org/PathwayBrowser/#/R-BTA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Bos taurus 15378 R-BTA-73577 https://reactome.org/PathwayBrowser/#/R-BTA-73577 CAD hexamer transforms L-Gln to CAP IEA Bos taurus 15378 R-BTA-73585 https://reactome.org/PathwayBrowser/#/R-BTA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Bos taurus 15378 R-BTA-73589 https://reactome.org/PathwayBrowser/#/R-BTA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Bos taurus 15378 R-BTA-73591 https://reactome.org/PathwayBrowser/#/R-BTA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Bos taurus 15378 R-BTA-73596 https://reactome.org/PathwayBrowser/#/R-BTA-73596 dCMP + H2O => dUMP + NH4+ IEA Bos taurus 15378 R-BTA-73616 https://reactome.org/PathwayBrowser/#/R-BTA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Bos taurus 15378 R-BTA-73618 https://reactome.org/PathwayBrowser/#/R-BTA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Bos taurus 15378 R-BTA-73620 https://reactome.org/PathwayBrowser/#/R-BTA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Bos taurus 15378 R-BTA-73646 https://reactome.org/PathwayBrowser/#/R-BTA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Bos taurus 15378 R-BTA-73647 https://reactome.org/PathwayBrowser/#/R-BTA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Bos taurus 15378 R-BTA-73666 https://reactome.org/PathwayBrowser/#/R-BTA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Bos taurus 15378 R-BTA-73792 https://reactome.org/PathwayBrowser/#/R-BTA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Bos taurus 15378 R-BTA-73794 https://reactome.org/PathwayBrowser/#/R-BTA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Bos taurus 15378 R-BTA-73805 https://reactome.org/PathwayBrowser/#/R-BTA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Bos taurus 15378 R-BTA-73806 https://reactome.org/PathwayBrowser/#/R-BTA-73806 AIR + CO2 => CAIR IEA Bos taurus 15378 R-BTA-73810 https://reactome.org/PathwayBrowser/#/R-BTA-73810 FGAM + ATP => AIR + ADP + Pi IEA Bos taurus 15378 R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 15378 R-BTA-73813 https://reactome.org/PathwayBrowser/#/R-BTA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Bos taurus 15378 R-BTA-73814 https://reactome.org/PathwayBrowser/#/R-BTA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Bos taurus 15378 R-BTA-73912 https://reactome.org/PathwayBrowser/#/R-BTA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Bos taurus 15378 R-BTA-73920 https://reactome.org/PathwayBrowser/#/R-BTA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Bos taurus 15378 R-BTA-74255 https://reactome.org/PathwayBrowser/#/R-BTA-74255 Guanine + H2O => Xanthine + NH4+ IEA Bos taurus 15378 R-BTA-74723 https://reactome.org/PathwayBrowser/#/R-BTA-74723 Endosome acidification IEA Bos taurus 15378 R-BTA-74872 https://reactome.org/PathwayBrowser/#/R-BTA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Bos taurus 15378 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15378 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15378 R-BTA-75872 https://reactome.org/PathwayBrowser/#/R-BTA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Bos taurus 15378 R-BTA-75883 https://reactome.org/PathwayBrowser/#/R-BTA-75883 DHRS7B reduces GO3P to HXDG3P IEA Bos taurus 15378 R-BTA-75889 https://reactome.org/PathwayBrowser/#/R-BTA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Bos taurus 15378 R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 15378 R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 15378 R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 15378 R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 15378 R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 15378 R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 15378 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 15378 R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 15378 R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 15378 R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 15378 R-BTA-77254 https://reactome.org/PathwayBrowser/#/R-BTA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Bos taurus 15378 R-BTA-77283 https://reactome.org/PathwayBrowser/#/R-BTA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Bos taurus 15378 R-BTA-77303 https://reactome.org/PathwayBrowser/#/R-BTA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Bos taurus 15378 R-BTA-77312 https://reactome.org/PathwayBrowser/#/R-BTA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Bos taurus 15378 R-BTA-77323 https://reactome.org/PathwayBrowser/#/R-BTA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Bos taurus 15378 R-BTA-77331 https://reactome.org/PathwayBrowser/#/R-BTA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Bos taurus 15378 R-BTA-77342 https://reactome.org/PathwayBrowser/#/R-BTA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Bos taurus 15378 R-BTA-804969 https://reactome.org/PathwayBrowser/#/R-BTA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Bos taurus 15378 R-BTA-8847579 https://reactome.org/PathwayBrowser/#/R-BTA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Bos taurus 15378 R-BTA-8849638 https://reactome.org/PathwayBrowser/#/R-BTA-8849638 Dissociation of the SPINK5:KLK5 complex at low pH IEA Bos taurus 15378 R-BTA-8850846 https://reactome.org/PathwayBrowser/#/R-BTA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-BTA-8850854 https://reactome.org/PathwayBrowser/#/R-BTA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-BTA-8851110 https://reactome.org/PathwayBrowser/#/R-BTA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-BTA-8851129 https://reactome.org/PathwayBrowser/#/R-BTA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 15378 R-BTA-8862137 https://reactome.org/PathwayBrowser/#/R-BTA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 15378 R-BTA-8862152 https://reactome.org/PathwayBrowser/#/R-BTA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Bos taurus 15378 R-BTA-8863494 https://reactome.org/PathwayBrowser/#/R-BTA-8863494 ASICs bind STOML3, (STOM) IEA Bos taurus 15378 R-BTA-8866601 https://reactome.org/PathwayBrowser/#/R-BTA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Bos taurus 15378 R-BTA-8869606 https://reactome.org/PathwayBrowser/#/R-BTA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Bos taurus 15378 R-BTA-8869607 https://reactome.org/PathwayBrowser/#/R-BTA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Bos taurus 15378 R-BTA-8869627 https://reactome.org/PathwayBrowser/#/R-BTA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Bos taurus 15378 R-BTA-8869633 https://reactome.org/PathwayBrowser/#/R-BTA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Bos taurus 15378 R-BTA-8870346 https://reactome.org/PathwayBrowser/#/R-BTA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Bos taurus 15378 R-BTA-8875623 https://reactome.org/PathwayBrowser/#/R-BTA-8875623 SLC25A18,22 import L-Glu, H+ IEA Bos taurus 15378 R-BTA-888548 https://reactome.org/PathwayBrowser/#/R-BTA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Bos taurus 15378 R-BTA-888572 https://reactome.org/PathwayBrowser/#/R-BTA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Bos taurus 15378 R-BTA-888577 https://reactome.org/PathwayBrowser/#/R-BTA-888577 Synthesis of GABA by GAD2 IEA Bos taurus 15378 R-BTA-8933635 https://reactome.org/PathwayBrowser/#/R-BTA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Bos taurus 15378 R-BTA-8936442 https://reactome.org/PathwayBrowser/#/R-BTA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Bos taurus 15378 R-BTA-8938076 https://reactome.org/PathwayBrowser/#/R-BTA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Bos taurus 15378 R-BTA-8952873 https://reactome.org/PathwayBrowser/#/R-BTA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Bos taurus 15378 R-BTA-8954468 https://reactome.org/PathwayBrowser/#/R-BTA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Bos taurus 15378 R-BTA-8955030 https://reactome.org/PathwayBrowser/#/R-BTA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Bos taurus 15378 R-BTA-8955760 https://reactome.org/PathwayBrowser/#/R-BTA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Bos taurus 15378 R-BTA-8956458 https://reactome.org/PathwayBrowser/#/R-BTA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Bos taurus 15378 R-BTA-8959719 https://reactome.org/PathwayBrowser/#/R-BTA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Bos taurus 15378 R-BTA-9009950 https://reactome.org/PathwayBrowser/#/R-BTA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Bos taurus 15378 R-BTA-9011595 https://reactome.org/PathwayBrowser/#/R-BTA-9011595 GSTZ1 dimer dehalogenates DCA IEA Bos taurus 15378 R-BTA-9012016 https://reactome.org/PathwayBrowser/#/R-BTA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Bos taurus 15378 R-BTA-9012036 https://reactome.org/PathwayBrowser/#/R-BTA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Bos taurus 15378 R-BTA-9024993 https://reactome.org/PathwayBrowser/#/R-BTA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Bos taurus 15378 R-BTA-9027043 https://reactome.org/PathwayBrowser/#/R-BTA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Bos taurus 15378 R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 15378 R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 15378 R-BTA-9037761 https://reactome.org/PathwayBrowser/#/R-BTA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Bos taurus 15378 R-BTA-917811 https://reactome.org/PathwayBrowser/#/R-BTA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Bos taurus 15378 R-BTA-917841 https://reactome.org/PathwayBrowser/#/R-BTA-917841 Acidification of Tf:TfR1 containing endosome IEA Bos taurus 15378 R-BTA-917891 https://reactome.org/PathwayBrowser/#/R-BTA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Bos taurus 15378 R-BTA-917933 https://reactome.org/PathwayBrowser/#/R-BTA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Bos taurus 15378 R-BTA-917979 https://reactome.org/PathwayBrowser/#/R-BTA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Bos taurus 15378 R-BTA-937311 https://reactome.org/PathwayBrowser/#/R-BTA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Bos taurus 15378 R-BTA-9620103 https://reactome.org/PathwayBrowser/#/R-BTA-9620103 ALDH2 transforms GTN to NO IEA Bos taurus 15378 R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-BTA-9650165 https://reactome.org/PathwayBrowser/#/R-BTA-9650165 ASIC trimers bind H+ IEA Bos taurus 15378 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 15378 R-BTA-9705713 https://reactome.org/PathwayBrowser/#/R-BTA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Bos taurus 15378 R-BTA-9705714 https://reactome.org/PathwayBrowser/#/R-BTA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Bos taurus 15378 R-BTA-9709098 https://reactome.org/PathwayBrowser/#/R-BTA-9709098 DHFR dimer reduces FOLA to DHF IEA Bos taurus 15378 R-BTA-9727198 https://reactome.org/PathwayBrowser/#/R-BTA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Bos taurus 15378 R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 15378 R-BTA-9727349 https://reactome.org/PathwayBrowser/#/R-BTA-9727349 XDH dehydrogenates xanthine to form urate IEA Bos taurus 15378 R-BTA-9731228 https://reactome.org/PathwayBrowser/#/R-BTA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Bos taurus 15378 R-BTA-9731590 https://reactome.org/PathwayBrowser/#/R-BTA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Bos taurus 15378 R-BTA-9731613 https://reactome.org/PathwayBrowser/#/R-BTA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Bos taurus 15378 R-BTA-9731632 https://reactome.org/PathwayBrowser/#/R-BTA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Bos taurus 15378 R-BTA-9731661 https://reactome.org/PathwayBrowser/#/R-BTA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Bos taurus 15378 R-BTA-9748945 https://reactome.org/PathwayBrowser/#/R-BTA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Bos taurus 15378 R-BTA-9748957 https://reactome.org/PathwayBrowser/#/R-BTA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Bos taurus 15378 R-BTA-9748979 https://reactome.org/PathwayBrowser/#/R-BTA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Bos taurus 15378 R-BTA-9748983 https://reactome.org/PathwayBrowser/#/R-BTA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Bos taurus 15378 R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 15378 R-BTA-9749609 https://reactome.org/PathwayBrowser/#/R-BTA-9749609 BCHE hydrolyzes ASA- IEA Bos taurus 15378 R-BTA-9749647 https://reactome.org/PathwayBrowser/#/R-BTA-9749647 CES2 hydrolyzes ASA- IEA Bos taurus 15378 R-BTA-9749792 https://reactome.org/PathwayBrowser/#/R-BTA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Bos taurus 15378 R-BTA-9753285 https://reactome.org/PathwayBrowser/#/R-BTA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Bos taurus 15378 R-BTA-9755937 https://reactome.org/PathwayBrowser/#/R-BTA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Bos taurus 15378 R-BTA-9756134 https://reactome.org/PathwayBrowser/#/R-BTA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Bos taurus 15378 R-BTA-9756138 https://reactome.org/PathwayBrowser/#/R-BTA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Bos taurus 15378 R-BTA-9756156 https://reactome.org/PathwayBrowser/#/R-BTA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Bos taurus 15378 R-BTA-9756162 https://reactome.org/PathwayBrowser/#/R-BTA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Bos taurus 15378 R-BTA-9756169 https://reactome.org/PathwayBrowser/#/R-BTA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Bos taurus 15378 R-BTA-9756177 https://reactome.org/PathwayBrowser/#/R-BTA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Bos taurus 15378 R-BTA-9756180 https://reactome.org/PathwayBrowser/#/R-BTA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Bos taurus 15378 R-BTA-9756183 https://reactome.org/PathwayBrowser/#/R-BTA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Bos taurus 15378 R-BTA-975629 https://reactome.org/PathwayBrowser/#/R-BTA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Bos taurus 15378 R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 15378 R-BTA-9758674 https://reactome.org/PathwayBrowser/#/R-BTA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Bos taurus 15378 R-BTA-9758682 https://reactome.org/PathwayBrowser/#/R-BTA-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Bos taurus 15378 R-BTA-9759259 https://reactome.org/PathwayBrowser/#/R-BTA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Bos taurus 15378 R-BTA-9759549 https://reactome.org/PathwayBrowser/#/R-BTA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Bos taurus 15378 R-BTA-9760094 https://reactome.org/PathwayBrowser/#/R-BTA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Bos taurus 15378 R-BTA-977348 https://reactome.org/PathwayBrowser/#/R-BTA-977348 PHGDH tetramer dehydrogenates 3PG IEA Bos taurus 15378 R-BTA-9794270 https://reactome.org/PathwayBrowser/#/R-BTA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Bos taurus 15378 R-BTA-9837337 https://reactome.org/PathwayBrowser/#/R-BTA-9837337 DCAKD phosphorylates DP-CoA IEA Bos taurus 15378 R-BTA-9843721 https://reactome.org/PathwayBrowser/#/R-BTA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Bos taurus 15378 R-BTA-9844587 https://reactome.org/PathwayBrowser/#/R-BTA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Bos taurus 15378 R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 15378 R-BTA-9845516 https://reactome.org/PathwayBrowser/#/R-BTA-9845516 B3GALT4 transfers Gal to gangliosides IEA Bos taurus 15378 R-BTA-9845538 https://reactome.org/PathwayBrowser/#/R-BTA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Bos taurus 15378 R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 15378 R-BTA-9846305 https://reactome.org/PathwayBrowser/#/R-BTA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Bos taurus 15378 R-BTA-9846332 https://reactome.org/PathwayBrowser/#/R-BTA-9846332 FUT1,2 transfer fucose to gangliosides IEA Bos taurus 15378 R-BTA-9846477 https://reactome.org/PathwayBrowser/#/R-BTA-9846477 A4GALT transfers galactose to LacCer IEA Bos taurus 15378 R-BTA-9846501 https://reactome.org/PathwayBrowser/#/R-BTA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Bos taurus 15378 R-BTA-9851347 https://reactome.org/PathwayBrowser/#/R-BTA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Bos taurus 15378 R-BTA-9853499 https://reactome.org/PathwayBrowser/#/R-BTA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 15378 R-BTA-9854315 https://reactome.org/PathwayBrowser/#/R-BTA-9854315 CSKMT methylates Citrate Synthase IEA Bos taurus 15378 R-BTA-9854415 https://reactome.org/PathwayBrowser/#/R-BTA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Bos taurus 15378 R-BTA-9856871 https://reactome.org/PathwayBrowser/#/R-BTA-9856871 MDH1 reduces OA IEA Bos taurus 15378 R-BTA-9861616 https://reactome.org/PathwayBrowser/#/R-BTA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 15378 R-BTA-9861642 https://reactome.org/PathwayBrowser/#/R-BTA-9861642 NEK1 phosphorylates ME1 IEA Bos taurus 15378 R-BTA-9861660 https://reactome.org/PathwayBrowser/#/R-BTA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Bos taurus 15378 R-BTA-9861734 https://reactome.org/PathwayBrowser/#/R-BTA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Bos taurus 15378 R-CEL-109343 https://reactome.org/PathwayBrowser/#/R-CEL-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Caenorhabditis elegans 15378 R-CEL-111524 https://reactome.org/PathwayBrowser/#/R-CEL-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Caenorhabditis elegans 15378 R-CEL-1222516 https://reactome.org/PathwayBrowser/#/R-CEL-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Caenorhabditis elegans 15378 R-CEL-1237045 https://reactome.org/PathwayBrowser/#/R-CEL-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Caenorhabditis elegans 15378 R-CEL-1237047 https://reactome.org/PathwayBrowser/#/R-CEL-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Caenorhabditis elegans 15378 R-CEL-1237059 https://reactome.org/PathwayBrowser/#/R-CEL-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Caenorhabditis elegans 15378 R-CEL-1237081 https://reactome.org/PathwayBrowser/#/R-CEL-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Caenorhabditis elegans 15378 R-CEL-1237129 https://reactome.org/PathwayBrowser/#/R-CEL-1237129 Acireductone is created IEA Caenorhabditis elegans 15378 R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 15378 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 15378 R-CEL-1475017 https://reactome.org/PathwayBrowser/#/R-CEL-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Caenorhabditis elegans 15378 R-CEL-1475022 https://reactome.org/PathwayBrowser/#/R-CEL-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Caenorhabditis elegans 15378 R-CEL-1475025 https://reactome.org/PathwayBrowser/#/R-CEL-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Caenorhabditis elegans 15378 R-CEL-1475026 https://reactome.org/PathwayBrowser/#/R-CEL-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Caenorhabditis elegans 15378 R-CEL-1475028 https://reactome.org/PathwayBrowser/#/R-CEL-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Caenorhabditis elegans 15378 R-CEL-1475032 https://reactome.org/PathwayBrowser/#/R-CEL-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Caenorhabditis elegans 15378 R-CEL-1475435 https://reactome.org/PathwayBrowser/#/R-CEL-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Caenorhabditis elegans 15378 R-CEL-1475436 https://reactome.org/PathwayBrowser/#/R-CEL-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Caenorhabditis elegans 15378 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 15378 R-CEL-1562626 https://reactome.org/PathwayBrowser/#/R-CEL-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Caenorhabditis elegans 15378 R-CEL-156526 https://reactome.org/PathwayBrowser/#/R-CEL-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Caenorhabditis elegans 15378 R-CEL-1605797 https://reactome.org/PathwayBrowser/#/R-CEL-1605797 SMPD1 hydrolyzes SPHM IEA Caenorhabditis elegans 15378 R-CEL-1606273 https://reactome.org/PathwayBrowser/#/R-CEL-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Caenorhabditis elegans 15378 R-CEL-1606288 https://reactome.org/PathwayBrowser/#/R-CEL-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Caenorhabditis elegans 15378 R-CEL-1614605 https://reactome.org/PathwayBrowser/#/R-CEL-1614605 Persulfide sulfur is dioxygenated IEA Caenorhabditis elegans 15378 R-CEL-1638104 https://reactome.org/PathwayBrowser/#/R-CEL-1638104 UGCG transfers glucose to ceramide IEA Caenorhabditis elegans 15378 R-CEL-1638845 https://reactome.org/PathwayBrowser/#/R-CEL-1638845 CERK phosphorylates CERA to form C1P IEA Caenorhabditis elegans 15378 R-CEL-1640164 https://reactome.org/PathwayBrowser/#/R-CEL-1640164 ENPP7 hydrolyzes sphingomyelin IEA Caenorhabditis elegans 15378 R-CEL-164651 https://reactome.org/PathwayBrowser/#/R-CEL-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Caenorhabditis elegans 15378 R-CEL-164834 https://reactome.org/PathwayBrowser/#/R-CEL-164834 Enzyme-bound ATP is released IEA Caenorhabditis elegans 15378 R-CEL-1655453 https://reactome.org/PathwayBrowser/#/R-CEL-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Caenorhabditis elegans 15378 R-CEL-170026 https://reactome.org/PathwayBrowser/#/R-CEL-170026 Protons are translocated from the intermembrane space to the matrix IEA Caenorhabditis elegans 15378 R-CEL-173597 https://reactome.org/PathwayBrowser/#/R-CEL-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Caenorhabditis elegans 15378 R-CEL-174389 https://reactome.org/PathwayBrowser/#/R-CEL-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Caenorhabditis elegans 15378 R-CEL-174392 https://reactome.org/PathwayBrowser/#/R-CEL-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Caenorhabditis elegans 15378 R-CEL-189465 https://reactome.org/PathwayBrowser/#/R-CEL-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Caenorhabditis elegans 15378 R-CEL-191323 https://reactome.org/PathwayBrowser/#/R-CEL-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Caenorhabditis elegans 15378 R-CEL-191352 https://reactome.org/PathwayBrowser/#/R-CEL-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Caenorhabditis elegans 15378 R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 15378 R-CEL-192033 https://reactome.org/PathwayBrowser/#/R-CEL-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Caenorhabditis elegans 15378 R-CEL-192036 https://reactome.org/PathwayBrowser/#/R-CEL-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Caenorhabditis elegans 15378 R-CEL-192067 https://reactome.org/PathwayBrowser/#/R-CEL-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Caenorhabditis elegans 15378 R-CEL-192160 https://reactome.org/PathwayBrowser/#/R-CEL-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Caenorhabditis elegans 15378 R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 15378 R-CEL-193064 https://reactome.org/PathwayBrowser/#/R-CEL-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Caenorhabditis elegans 15378 R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 15378 R-CEL-193455 https://reactome.org/PathwayBrowser/#/R-CEL-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 15378 R-CEL-193508 https://reactome.org/PathwayBrowser/#/R-CEL-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 15378 R-CEL-193746 https://reactome.org/PathwayBrowser/#/R-CEL-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Caenorhabditis elegans 15378 R-CEL-193755 https://reactome.org/PathwayBrowser/#/R-CEL-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Caenorhabditis elegans 15378 R-CEL-193758 https://reactome.org/PathwayBrowser/#/R-CEL-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Caenorhabditis elegans 15378 R-CEL-193781 https://reactome.org/PathwayBrowser/#/R-CEL-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Caenorhabditis elegans 15378 R-CEL-193800 https://reactome.org/PathwayBrowser/#/R-CEL-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Caenorhabditis elegans 15378 R-CEL-193821 https://reactome.org/PathwayBrowser/#/R-CEL-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Caenorhabditis elegans 15378 R-CEL-193824 https://reactome.org/PathwayBrowser/#/R-CEL-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Caenorhabditis elegans 15378 R-CEL-193841 https://reactome.org/PathwayBrowser/#/R-CEL-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Caenorhabditis elegans 15378 R-CEL-194642 https://reactome.org/PathwayBrowser/#/R-CEL-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Caenorhabditis elegans 15378 R-CEL-194718 https://reactome.org/PathwayBrowser/#/R-CEL-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Caenorhabditis elegans 15378 R-CEL-196060 https://reactome.org/PathwayBrowser/#/R-CEL-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Caenorhabditis elegans 15378 R-CEL-196402 https://reactome.org/PathwayBrowser/#/R-CEL-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Caenorhabditis elegans 15378 R-CEL-196417 https://reactome.org/PathwayBrowser/#/R-CEL-196417 Reduction of desmosterol to cholesterol IEA Caenorhabditis elegans 15378 R-CEL-196753 https://reactome.org/PathwayBrowser/#/R-CEL-196753 2xPPCS ligates PPanK with Cys IEA Caenorhabditis elegans 15378 R-CEL-196754 https://reactome.org/PathwayBrowser/#/R-CEL-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Caenorhabditis elegans 15378 R-CEL-196773 https://reactome.org/PathwayBrowser/#/R-CEL-196773 COASY phosphorylates DP-CoA IEA Caenorhabditis elegans 15378 R-CEL-196840 https://reactome.org/PathwayBrowser/#/R-CEL-196840 3xPPCDC:3FMN decarboxylates PPC IEA Caenorhabditis elegans 15378 R-CEL-196929 https://reactome.org/PathwayBrowser/#/R-CEL-196929 FLAD1 phosphorylates FMN IEA Caenorhabditis elegans 15378 R-CEL-196955 https://reactome.org/PathwayBrowser/#/R-CEL-196955 2xENPP1 hydrolyzes FAD to FMN IEA Caenorhabditis elegans 15378 R-CEL-196964 https://reactome.org/PathwayBrowser/#/R-CEL-196964 RFK:Mg2+ phosphorylates RIB IEA Caenorhabditis elegans 15378 R-CEL-197186 https://reactome.org/PathwayBrowser/#/R-CEL-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Caenorhabditis elegans 15378 R-CEL-197963 https://reactome.org/PathwayBrowser/#/R-CEL-197963 DHFR2 reduces FOLA to DHF IEA Caenorhabditis elegans 15378 R-CEL-197972 https://reactome.org/PathwayBrowser/#/R-CEL-197972 DHF is reduced to tetrahydrofolate (THF) IEA Caenorhabditis elegans 15378 R-CEL-200644 https://reactome.org/PathwayBrowser/#/R-CEL-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Caenorhabditis elegans 15378 R-CEL-200676 https://reactome.org/PathwayBrowser/#/R-CEL-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Caenorhabditis elegans 15378 R-CEL-200718 https://reactome.org/PathwayBrowser/#/R-CEL-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Caenorhabditis elegans 15378 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 15378 R-CEL-204617 https://reactome.org/PathwayBrowser/#/R-CEL-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Caenorhabditis elegans 15378 R-CEL-204647 https://reactome.org/PathwayBrowser/#/R-CEL-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Caenorhabditis elegans 15378 R-CEL-204662 https://reactome.org/PathwayBrowser/#/R-CEL-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Caenorhabditis elegans 15378 R-CEL-209845 https://reactome.org/PathwayBrowser/#/R-CEL-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Caenorhabditis elegans 15378 R-CEL-209903 https://reactome.org/PathwayBrowser/#/R-CEL-209903 Noradrenaline is converted to adrenaline IEA Caenorhabditis elegans 15378 R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 15378 R-CEL-210404 https://reactome.org/PathwayBrowser/#/R-CEL-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Caenorhabditis elegans 15378 R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 15378 R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 15378 R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 15378 R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 15378 R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 15378 R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 15378 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 15378 R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 15378 R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 15378 R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 15378 R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 15378 R-CEL-2161187 https://reactome.org/PathwayBrowser/#/R-CEL-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Caenorhabditis elegans 15378 R-CEL-2161549 https://reactome.org/PathwayBrowser/#/R-CEL-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Caenorhabditis elegans 15378 R-CEL-2161614 https://reactome.org/PathwayBrowser/#/R-CEL-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Caenorhabditis elegans 15378 R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 15378 R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans 15378 R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Caenorhabditis elegans 15378 R-CEL-2162078 https://reactome.org/PathwayBrowser/#/R-CEL-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Caenorhabditis elegans 15378 R-CEL-2162186 https://reactome.org/PathwayBrowser/#/R-CEL-2162186 COQ3 methylates DeMQ10H2 IEA Caenorhabditis elegans 15378 R-CEL-2162188 https://reactome.org/PathwayBrowser/#/R-CEL-2162188 COQ5 methylates MDMQ10H2 IEA Caenorhabditis elegans 15378 R-CEL-2162193 https://reactome.org/PathwayBrowser/#/R-CEL-2162193 COQ3 methylates DHDB IEA Caenorhabditis elegans 15378 R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 15378 R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 15378 R-CEL-2395512 https://reactome.org/PathwayBrowser/#/R-CEL-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Caenorhabditis elegans 15378 R-CEL-2395517 https://reactome.org/PathwayBrowser/#/R-CEL-2395517 NADPH transfers electrons to FDXR IEA Caenorhabditis elegans 15378 R-CEL-2395873 https://reactome.org/PathwayBrowser/#/R-CEL-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Caenorhabditis elegans 15378 R-CEL-2395879 https://reactome.org/PathwayBrowser/#/R-CEL-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Caenorhabditis elegans 15378 R-CEL-2395965 https://reactome.org/PathwayBrowser/#/R-CEL-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Caenorhabditis elegans 15378 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 15378 R-CEL-2465940 https://reactome.org/PathwayBrowser/#/R-CEL-2465940 atRAL is reduced to atROL IEA Caenorhabditis elegans 15378 R-CEL-2509827 https://reactome.org/PathwayBrowser/#/R-CEL-2509827 ITPA hydrolyses ITP to IMP IEA Caenorhabditis elegans 15378 R-CEL-2509831 https://reactome.org/PathwayBrowser/#/R-CEL-2509831 ITPA hydrolyses XTP to XMP IEA Caenorhabditis elegans 15378 R-CEL-2509838 https://reactome.org/PathwayBrowser/#/R-CEL-2509838 ITPA hydrolyses dITP to dIMP IEA Caenorhabditis elegans 15378 R-CEL-264615 https://reactome.org/PathwayBrowser/#/R-CEL-264615 Loading of acetylcholine in synaptic vesicles IEA Caenorhabditis elegans 15378 R-CEL-2671885 https://reactome.org/PathwayBrowser/#/R-CEL-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Caenorhabditis elegans 15378 R-CEL-2730692 https://reactome.org/PathwayBrowser/#/R-CEL-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Caenorhabditis elegans 15378 R-CEL-2730959 https://reactome.org/PathwayBrowser/#/R-CEL-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Caenorhabditis elegans 15378 R-CEL-2855252 https://reactome.org/PathwayBrowser/#/R-CEL-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Caenorhabditis elegans 15378 R-CEL-2872444 https://reactome.org/PathwayBrowser/#/R-CEL-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Caenorhabditis elegans 15378 R-CEL-2889070 https://reactome.org/PathwayBrowser/#/R-CEL-2889070 SLC9B2 exchanges Na+ for H+ IEA Caenorhabditis elegans 15378 R-CEL-3095889 https://reactome.org/PathwayBrowser/#/R-CEL-3095889 MMACHC dealkylates RCbl IEA Caenorhabditis elegans 15378 R-CEL-3149518 https://reactome.org/PathwayBrowser/#/R-CEL-3149518 MTRR reduces cob(II)alamin to meCbl IEA Caenorhabditis elegans 15378 R-CEL-3149519 https://reactome.org/PathwayBrowser/#/R-CEL-3149519 MMACHC decyanates CNCbl IEA Caenorhabditis elegans 15378 R-CEL-3159253 https://reactome.org/PathwayBrowser/#/R-CEL-3159253 MMAB adenosylates cob(I)alamin IEA Caenorhabditis elegans 15378 R-CEL-3299680 https://reactome.org/PathwayBrowser/#/R-CEL-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Caenorhabditis elegans 15378 R-CEL-3299691 https://reactome.org/PathwayBrowser/#/R-CEL-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Caenorhabditis elegans 15378 R-CEL-3323050 https://reactome.org/PathwayBrowser/#/R-CEL-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Caenorhabditis elegans 15378 R-CEL-3323079 https://reactome.org/PathwayBrowser/#/R-CEL-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 15378 R-CEL-350901 https://reactome.org/PathwayBrowser/#/R-CEL-350901 Iodide is organified IEA Caenorhabditis elegans 15378 R-CEL-372448 https://reactome.org/PathwayBrowser/#/R-CEL-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Caenorhabditis elegans 15378 R-CEL-373867 https://reactome.org/PathwayBrowser/#/R-CEL-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-CEL-373875 https://reactome.org/PathwayBrowser/#/R-CEL-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Caenorhabditis elegans 15378 R-CEL-375405 https://reactome.org/PathwayBrowser/#/R-CEL-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-CEL-375417 https://reactome.org/PathwayBrowser/#/R-CEL-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Caenorhabditis elegans 15378 R-CEL-3777112 https://reactome.org/PathwayBrowser/#/R-CEL-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Caenorhabditis elegans 15378 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 15378 R-CEL-380608 https://reactome.org/PathwayBrowser/#/R-CEL-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Caenorhabditis elegans 15378 R-CEL-389540 https://reactome.org/PathwayBrowser/#/R-CEL-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 15378 R-CEL-389550 https://reactome.org/PathwayBrowser/#/R-CEL-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 15378 R-CEL-389609 https://reactome.org/PathwayBrowser/#/R-CEL-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Caenorhabditis elegans 15378 R-CEL-389995 https://reactome.org/PathwayBrowser/#/R-CEL-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Caenorhabditis elegans 15378 R-CEL-390251 https://reactome.org/PathwayBrowser/#/R-CEL-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 15378 R-CEL-390425 https://reactome.org/PathwayBrowser/#/R-CEL-390425 FAR1 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 15378 R-CEL-390438 https://reactome.org/PathwayBrowser/#/R-CEL-390438 FAR2 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 15378 R-CEL-418365 https://reactome.org/PathwayBrowser/#/R-CEL-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Caenorhabditis elegans 15378 R-CEL-425577 https://reactome.org/PathwayBrowser/#/R-CEL-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Caenorhabditis elegans 15378 R-CEL-425965 https://reactome.org/PathwayBrowser/#/R-CEL-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Caenorhabditis elegans 15378 R-CEL-425983 https://reactome.org/PathwayBrowser/#/R-CEL-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Caenorhabditis elegans 15378 R-CEL-425994 https://reactome.org/PathwayBrowser/#/R-CEL-425994 Na+/H+ exchanger transport (at cell membrane) IEA Caenorhabditis elegans 15378 R-CEL-426015 https://reactome.org/PathwayBrowser/#/R-CEL-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Caenorhabditis elegans 15378 R-CEL-427555 https://reactome.org/PathwayBrowser/#/R-CEL-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-CEL-427910 https://reactome.org/PathwayBrowser/#/R-CEL-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Caenorhabditis elegans 15378 R-CEL-427998 https://reactome.org/PathwayBrowser/#/R-CEL-427998 Proton-coupled di- and tri-peptide cotransport IEA Caenorhabditis elegans 15378 R-CEL-428015 https://reactome.org/PathwayBrowser/#/R-CEL-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-CEL-428052 https://reactome.org/PathwayBrowser/#/R-CEL-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Caenorhabditis elegans 15378 R-CEL-428123 https://reactome.org/PathwayBrowser/#/R-CEL-428123 KDSR reduces 3-ketosphingoid IEA Caenorhabditis elegans 15378 R-CEL-428185 https://reactome.org/PathwayBrowser/#/R-CEL-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Caenorhabditis elegans 15378 R-CEL-428259 https://reactome.org/PathwayBrowser/#/R-CEL-428259 DEGS1 dehydrogenates dihydroceramide IEA Caenorhabditis elegans 15378 R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 15378 R-CEL-428273 https://reactome.org/PathwayBrowser/#/R-CEL-428273 SPHK1 phosphorylates sphingoid IEA Caenorhabditis elegans 15378 R-CEL-428585 https://reactome.org/PathwayBrowser/#/R-CEL-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Caenorhabditis elegans 15378 R-CEL-428625 https://reactome.org/PathwayBrowser/#/R-CEL-428625 Vesicular inhibitory amino acid transport IEA Caenorhabditis elegans 15378 R-CEL-429101 https://reactome.org/PathwayBrowser/#/R-CEL-429101 HMIT co-transports myo-inositol with a proton IEA Caenorhabditis elegans 15378 R-CEL-429157 https://reactome.org/PathwayBrowser/#/R-CEL-429157 ABCC4 accumulation of dense granule contents IEA Caenorhabditis elegans 15378 R-CEL-429698 https://reactome.org/PathwayBrowser/#/R-CEL-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Caenorhabditis elegans 15378 R-CEL-429714 https://reactome.org/PathwayBrowser/#/R-CEL-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Caenorhabditis elegans 15378 R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-CEL-435171 https://reactome.org/PathwayBrowser/#/R-CEL-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Caenorhabditis elegans 15378 R-CEL-435349 https://reactome.org/PathwayBrowser/#/R-CEL-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-CEL-444393 https://reactome.org/PathwayBrowser/#/R-CEL-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-CEL-444419 https://reactome.org/PathwayBrowser/#/R-CEL-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-CEL-444731 https://reactome.org/PathwayBrowser/#/R-CEL-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Caenorhabditis elegans 15378 R-CEL-446277 https://reactome.org/PathwayBrowser/#/R-CEL-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-CEL-446278 https://reactome.org/PathwayBrowser/#/R-CEL-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-CEL-450971 https://reactome.org/PathwayBrowser/#/R-CEL-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Caenorhabditis elegans 15378 R-CEL-469659 https://reactome.org/PathwayBrowser/#/R-CEL-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 15378 R-CEL-504054 https://reactome.org/PathwayBrowser/#/R-CEL-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Caenorhabditis elegans 15378 R-CEL-508040 https://reactome.org/PathwayBrowser/#/R-CEL-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Caenorhabditis elegans 15378 R-CEL-508369 https://reactome.org/PathwayBrowser/#/R-CEL-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Caenorhabditis elegans 15378 R-CEL-508473 https://reactome.org/PathwayBrowser/#/R-CEL-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Caenorhabditis elegans 15378 R-CEL-514604 https://reactome.org/PathwayBrowser/#/R-CEL-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Caenorhabditis elegans 15378 R-CEL-5263614 https://reactome.org/PathwayBrowser/#/R-CEL-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Caenorhabditis elegans 15378 R-CEL-5263616 https://reactome.org/PathwayBrowser/#/R-CEL-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Caenorhabditis elegans 15378 R-CEL-5340130 https://reactome.org/PathwayBrowser/#/R-CEL-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Caenorhabditis elegans 15378 R-CEL-5340226 https://reactome.org/PathwayBrowser/#/R-CEL-5340226 CYGB dioxygenates NO IEA Caenorhabditis elegans 15378 R-CEL-5362518 https://reactome.org/PathwayBrowser/#/R-CEL-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Caenorhabditis elegans 15378 R-CEL-5362522 https://reactome.org/PathwayBrowser/#/R-CEL-5362522 ALDHs oxidise atRAL to atRA IEA Caenorhabditis elegans 15378 R-CEL-5362564 https://reactome.org/PathwayBrowser/#/R-CEL-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Caenorhabditis elegans 15378 R-CEL-5362721 https://reactome.org/PathwayBrowser/#/R-CEL-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Caenorhabditis elegans 15378 R-CEL-5419165 https://reactome.org/PathwayBrowser/#/R-CEL-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Caenorhabditis elegans 15378 R-CEL-5423647 https://reactome.org/PathwayBrowser/#/R-CEL-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Caenorhabditis elegans 15378 R-CEL-548818 https://reactome.org/PathwayBrowser/#/R-CEL-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Caenorhabditis elegans 15378 R-CEL-548831 https://reactome.org/PathwayBrowser/#/R-CEL-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Caenorhabditis elegans 15378 R-CEL-5615668 https://reactome.org/PathwayBrowser/#/R-CEL-5615668 AKR1C3 reduces atRAL to atROL IEA Caenorhabditis elegans 15378 R-CEL-5623643 https://reactome.org/PathwayBrowser/#/R-CEL-5623643 RDH13 reduces atRAL to atROL IEA Caenorhabditis elegans 15378 R-CEL-5652172 https://reactome.org/PathwayBrowser/#/R-CEL-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Caenorhabditis elegans 15378 R-CEL-5652195 https://reactome.org/PathwayBrowser/#/R-CEL-5652195 SORD oxidizes D-sorbitol to Fru IEA Caenorhabditis elegans 15378 R-CEL-5661240 https://reactome.org/PathwayBrowser/#/R-CEL-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Caenorhabditis elegans 15378 R-CEL-5661256 https://reactome.org/PathwayBrowser/#/R-CEL-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Caenorhabditis elegans 15378 R-CEL-5661290 https://reactome.org/PathwayBrowser/#/R-CEL-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Caenorhabditis elegans 15378 R-CEL-5662471 https://reactome.org/PathwayBrowser/#/R-CEL-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Caenorhabditis elegans 15378 R-CEL-5662662 https://reactome.org/PathwayBrowser/#/R-CEL-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Caenorhabditis elegans 15378 R-CEL-5678327 https://reactome.org/PathwayBrowser/#/R-CEL-5678327 MIOX oxidises Ins to GlcA IEA Caenorhabditis elegans 15378 R-CEL-5690565 https://reactome.org/PathwayBrowser/#/R-CEL-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15378 R-CEL-5691107 https://reactome.org/PathwayBrowser/#/R-CEL-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Caenorhabditis elegans 15378 R-CEL-5692237 https://reactome.org/PathwayBrowser/#/R-CEL-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Caenorhabditis elegans 15378 R-CEL-5692261 https://reactome.org/PathwayBrowser/#/R-CEL-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Caenorhabditis elegans 15378 R-CEL-5692283 https://reactome.org/PathwayBrowser/#/R-CEL-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Caenorhabditis elegans 15378 R-CEL-5693681 https://reactome.org/PathwayBrowser/#/R-CEL-5693681 DUOX1,2 reduce O2 to H2O2 IEA Caenorhabditis elegans 15378 R-CEL-5693691 https://reactome.org/PathwayBrowser/#/R-CEL-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Caenorhabditis elegans 15378 R-CEL-5693761 https://reactome.org/PathwayBrowser/#/R-CEL-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Caenorhabditis elegans 15378 R-CEL-5694018 https://reactome.org/PathwayBrowser/#/R-CEL-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Caenorhabditis elegans 15378 R-CEL-5694462 https://reactome.org/PathwayBrowser/#/R-CEL-5694462 ABHD6,12 hydrolyse 3AG IEA Caenorhabditis elegans 15378 R-CEL-5696080 https://reactome.org/PathwayBrowser/#/R-CEL-5696080 ALDH3B1 oxidises HXAL to PALM IEA Caenorhabditis elegans 15378 R-CEL-5696091 https://reactome.org/PathwayBrowser/#/R-CEL-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Caenorhabditis elegans 15378 R-CEL-5696101 https://reactome.org/PathwayBrowser/#/R-CEL-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Caenorhabditis elegans 15378 R-CEL-5696822 https://reactome.org/PathwayBrowser/#/R-CEL-5696822 AKR1B15 reduces EST17b to E1 IEA Caenorhabditis elegans 15378 R-CEL-597628 https://reactome.org/PathwayBrowser/#/R-CEL-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Caenorhabditis elegans 15378 R-CEL-6783221 https://reactome.org/PathwayBrowser/#/R-CEL-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Caenorhabditis elegans 15378 R-CEL-6783939 https://reactome.org/PathwayBrowser/#/R-CEL-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 15378 R-CEL-6785933 https://reactome.org/PathwayBrowser/#/R-CEL-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Caenorhabditis elegans 15378 R-CEL-6786239 https://reactome.org/PathwayBrowser/#/R-CEL-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Caenorhabditis elegans 15378 R-CEL-6787642 https://reactome.org/PathwayBrowser/#/R-CEL-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Caenorhabditis elegans 15378 R-CEL-6789031 https://reactome.org/PathwayBrowser/#/R-CEL-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 15378 R-CEL-6789126 https://reactome.org/PathwayBrowser/#/R-CEL-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 15378 R-CEL-6793590 https://reactome.org/PathwayBrowser/#/R-CEL-6793590 LIPT2 transfers octanoyl group to GCSH IEA Caenorhabditis elegans 15378 R-CEL-6799495 https://reactome.org/PathwayBrowser/#/R-CEL-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Caenorhabditis elegans 15378 R-CEL-6801342 https://reactome.org/PathwayBrowser/#/R-CEL-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Caenorhabditis elegans 15378 R-CEL-6803771 https://reactome.org/PathwayBrowser/#/R-CEL-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Caenorhabditis elegans 15378 R-CEL-6806967 https://reactome.org/PathwayBrowser/#/R-CEL-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Caenorhabditis elegans 15378 R-CEL-6807055 https://reactome.org/PathwayBrowser/#/R-CEL-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Caenorhabditis elegans 15378 R-CEL-6807064 https://reactome.org/PathwayBrowser/#/R-CEL-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Caenorhabditis elegans 15378 R-CEL-6807826 https://reactome.org/PathwayBrowser/#/R-CEL-6807826 LDHAL6B reduces PYR to LACT IEA Caenorhabditis elegans 15378 R-CEL-6808464 https://reactome.org/PathwayBrowser/#/R-CEL-6808464 ALDH3B2 oxidises HXAL to PALM IEA Caenorhabditis elegans 15378 R-CEL-6808487 https://reactome.org/PathwayBrowser/#/R-CEL-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 15378 R-CEL-6808496 https://reactome.org/PathwayBrowser/#/R-CEL-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 15378 R-CEL-6809264 https://reactome.org/PathwayBrowser/#/R-CEL-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 15378 R-CEL-6809287 https://reactome.org/PathwayBrowser/#/R-CEL-6809287 NUDT12 hydrolyses NADH to NMNH IEA Caenorhabditis elegans 15378 R-CEL-6813749 https://reactome.org/PathwayBrowser/#/R-CEL-6813749 ALDH1A1 oxidises GA to DGA IEA Caenorhabditis elegans 15378 R-CEL-6814153 https://reactome.org/PathwayBrowser/#/R-CEL-6814153 ADO oxidises 2AET to HTAU IEA Caenorhabditis elegans 15378 R-CEL-70377 https://reactome.org/PathwayBrowser/#/R-CEL-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Caenorhabditis elegans 15378 R-CEL-70420 https://reactome.org/PathwayBrowser/#/R-CEL-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Caenorhabditis elegans 15378 R-CEL-70449 https://reactome.org/PathwayBrowser/#/R-CEL-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Caenorhabditis elegans 15378 R-CEL-70467 https://reactome.org/PathwayBrowser/#/R-CEL-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Caenorhabditis elegans 15378 R-CEL-70482 https://reactome.org/PathwayBrowser/#/R-CEL-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Caenorhabditis elegans 15378 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 15378 R-CEL-70510 https://reactome.org/PathwayBrowser/#/R-CEL-70510 LDH tetramer oxidises LACT to PYR IEA Caenorhabditis elegans 15378 R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Caenorhabditis elegans 15378 R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Caenorhabditis elegans 15378 R-CEL-70664 https://reactome.org/PathwayBrowser/#/R-CEL-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 15378 R-CEL-70670 https://reactome.org/PathwayBrowser/#/R-CEL-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Caenorhabditis elegans 15378 R-CEL-70837 https://reactome.org/PathwayBrowser/#/R-CEL-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Caenorhabditis elegans 15378 R-CEL-70885 https://reactome.org/PathwayBrowser/#/R-CEL-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Caenorhabditis elegans 15378 R-CEL-70893 https://reactome.org/PathwayBrowser/#/R-CEL-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 15378 R-CEL-70906 https://reactome.org/PathwayBrowser/#/R-CEL-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Caenorhabditis elegans 15378 R-CEL-70938 https://reactome.org/PathwayBrowser/#/R-CEL-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Caenorhabditis elegans 15378 R-CEL-70940 https://reactome.org/PathwayBrowser/#/R-CEL-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Caenorhabditis elegans 15378 R-CEL-70941 https://reactome.org/PathwayBrowser/#/R-CEL-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Caenorhabditis elegans 15378 R-CEL-70975 https://reactome.org/PathwayBrowser/#/R-CEL-70975 CS acetylates OA to citrate IEA Caenorhabditis elegans 15378 R-CEL-70979 https://reactome.org/PathwayBrowser/#/R-CEL-70979 MDH2 dimer dehydrogenates MAL IEA Caenorhabditis elegans 15378 R-CEL-71130 https://reactome.org/PathwayBrowser/#/R-CEL-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Caenorhabditis elegans 15378 R-CEL-71164 https://reactome.org/PathwayBrowser/#/R-CEL-71164 HGD dioxygenates homogentisate IEA Caenorhabditis elegans 15378 R-CEL-71181 https://reactome.org/PathwayBrowser/#/R-CEL-71181 FAH cleaves 4FAA IEA Caenorhabditis elegans 15378 R-CEL-71200 https://reactome.org/PathwayBrowser/#/R-CEL-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Caenorhabditis elegans 15378 R-CEL-71260 https://reactome.org/PathwayBrowser/#/R-CEL-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Caenorhabditis elegans 15378 R-CEL-71299 https://reactome.org/PathwayBrowser/#/R-CEL-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 15378 R-CEL-71401 https://reactome.org/PathwayBrowser/#/R-CEL-71401 OGDH dimer decarboxylates 2-OG IEA Caenorhabditis elegans 15378 R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 15378 R-CEL-71682 https://reactome.org/PathwayBrowser/#/R-CEL-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 15378 R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 15378 R-CEL-71707 https://reactome.org/PathwayBrowser/#/R-CEL-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Caenorhabditis elegans 15378 R-CEL-71723 https://reactome.org/PathwayBrowser/#/R-CEL-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Caenorhabditis elegans 15378 R-CEL-71849 https://reactome.org/PathwayBrowser/#/R-CEL-71849 LDH tetramer reduces PYR to LACT IEA Caenorhabditis elegans 15378 R-CEL-73564 https://reactome.org/PathwayBrowser/#/R-CEL-73564 UMPS dimer decarboxylates OMP to UMP IEA Caenorhabditis elegans 15378 R-CEL-73571 https://reactome.org/PathwayBrowser/#/R-CEL-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Caenorhabditis elegans 15378 R-CEL-73573 https://reactome.org/PathwayBrowser/#/R-CEL-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Caenorhabditis elegans 15378 R-CEL-73577 https://reactome.org/PathwayBrowser/#/R-CEL-73577 CAD hexamer transforms L-Gln to CAP IEA Caenorhabditis elegans 15378 R-CEL-73585 https://reactome.org/PathwayBrowser/#/R-CEL-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Caenorhabditis elegans 15378 R-CEL-73589 https://reactome.org/PathwayBrowser/#/R-CEL-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Caenorhabditis elegans 15378 R-CEL-73591 https://reactome.org/PathwayBrowser/#/R-CEL-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Caenorhabditis elegans 15378 R-CEL-73616 https://reactome.org/PathwayBrowser/#/R-CEL-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Caenorhabditis elegans 15378 R-CEL-73618 https://reactome.org/PathwayBrowser/#/R-CEL-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Caenorhabditis elegans 15378 R-CEL-73620 https://reactome.org/PathwayBrowser/#/R-CEL-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Caenorhabditis elegans 15378 R-CEL-73646 https://reactome.org/PathwayBrowser/#/R-CEL-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Caenorhabditis elegans 15378 R-CEL-73647 https://reactome.org/PathwayBrowser/#/R-CEL-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Caenorhabditis elegans 15378 R-CEL-73666 https://reactome.org/PathwayBrowser/#/R-CEL-73666 dUTP + H2O => dUMP + pyrophosphate IEA Caenorhabditis elegans 15378 R-CEL-73792 https://reactome.org/PathwayBrowser/#/R-CEL-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Caenorhabditis elegans 15378 R-CEL-73794 https://reactome.org/PathwayBrowser/#/R-CEL-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Caenorhabditis elegans 15378 R-CEL-73805 https://reactome.org/PathwayBrowser/#/R-CEL-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Caenorhabditis elegans 15378 R-CEL-73806 https://reactome.org/PathwayBrowser/#/R-CEL-73806 AIR + CO2 => CAIR IEA Caenorhabditis elegans 15378 R-CEL-73810 https://reactome.org/PathwayBrowser/#/R-CEL-73810 FGAM + ATP => AIR + ADP + Pi IEA Caenorhabditis elegans 15378 R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 15378 R-CEL-73813 https://reactome.org/PathwayBrowser/#/R-CEL-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Caenorhabditis elegans 15378 R-CEL-73814 https://reactome.org/PathwayBrowser/#/R-CEL-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Caenorhabditis elegans 15378 R-CEL-74723 https://reactome.org/PathwayBrowser/#/R-CEL-74723 Endosome acidification IEA Caenorhabditis elegans 15378 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 15378 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15378 R-CEL-75872 https://reactome.org/PathwayBrowser/#/R-CEL-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Caenorhabditis elegans 15378 R-CEL-75883 https://reactome.org/PathwayBrowser/#/R-CEL-75883 DHRS7B reduces GO3P to HXDG3P IEA Caenorhabditis elegans 15378 R-CEL-75889 https://reactome.org/PathwayBrowser/#/R-CEL-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Caenorhabditis elegans 15378 R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 15378 R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 15378 R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 15378 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 15378 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 15378 R-CEL-77254 https://reactome.org/PathwayBrowser/#/R-CEL-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-CEL-77283 https://reactome.org/PathwayBrowser/#/R-CEL-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-CEL-77303 https://reactome.org/PathwayBrowser/#/R-CEL-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-CEL-77312 https://reactome.org/PathwayBrowser/#/R-CEL-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-CEL-77323 https://reactome.org/PathwayBrowser/#/R-CEL-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-CEL-77331 https://reactome.org/PathwayBrowser/#/R-CEL-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-CEL-77342 https://reactome.org/PathwayBrowser/#/R-CEL-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-CEL-8847579 https://reactome.org/PathwayBrowser/#/R-CEL-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15378 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15378 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 15378 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15378 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15378 R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 15378 R-CEL-8863494 https://reactome.org/PathwayBrowser/#/R-CEL-8863494 ASICs bind STOML3, (STOM) IEA Caenorhabditis elegans 15378 R-CEL-8866601 https://reactome.org/PathwayBrowser/#/R-CEL-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Caenorhabditis elegans 15378 R-CEL-8875623 https://reactome.org/PathwayBrowser/#/R-CEL-8875623 SLC25A18,22 import L-Glu, H+ IEA Caenorhabditis elegans 15378 R-CEL-888548 https://reactome.org/PathwayBrowser/#/R-CEL-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Caenorhabditis elegans 15378 R-CEL-888572 https://reactome.org/PathwayBrowser/#/R-CEL-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Caenorhabditis elegans 15378 R-CEL-888577 https://reactome.org/PathwayBrowser/#/R-CEL-888577 Synthesis of GABA by GAD2 IEA Caenorhabditis elegans 15378 R-CEL-8933635 https://reactome.org/PathwayBrowser/#/R-CEL-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Caenorhabditis elegans 15378 R-CEL-8936442 https://reactome.org/PathwayBrowser/#/R-CEL-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Caenorhabditis elegans 15378 R-CEL-8952873 https://reactome.org/PathwayBrowser/#/R-CEL-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Caenorhabditis elegans 15378 R-CEL-8955030 https://reactome.org/PathwayBrowser/#/R-CEL-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Caenorhabditis elegans 15378 R-CEL-8955760 https://reactome.org/PathwayBrowser/#/R-CEL-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Caenorhabditis elegans 15378 R-CEL-8959510 https://reactome.org/PathwayBrowser/#/R-CEL-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Caenorhabditis elegans 15378 R-CEL-8959719 https://reactome.org/PathwayBrowser/#/R-CEL-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Caenorhabditis elegans 15378 R-CEL-9009950 https://reactome.org/PathwayBrowser/#/R-CEL-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Caenorhabditis elegans 15378 R-CEL-9011595 https://reactome.org/PathwayBrowser/#/R-CEL-9011595 GSTZ1 dimer dehalogenates DCA IEA Caenorhabditis elegans 15378 R-CEL-9012016 https://reactome.org/PathwayBrowser/#/R-CEL-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Caenorhabditis elegans 15378 R-CEL-9012036 https://reactome.org/PathwayBrowser/#/R-CEL-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 15378 R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans 15378 R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 15378 R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 15378 R-CEL-917841 https://reactome.org/PathwayBrowser/#/R-CEL-917841 Acidification of Tf:TfR1 containing endosome IEA Caenorhabditis elegans 15378 R-CEL-917979 https://reactome.org/PathwayBrowser/#/R-CEL-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Caenorhabditis elegans 15378 R-CEL-9620103 https://reactome.org/PathwayBrowser/#/R-CEL-9620103 ALDH2 transforms GTN to NO IEA Caenorhabditis elegans 15378 R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-CEL-9650165 https://reactome.org/PathwayBrowser/#/R-CEL-9650165 ASIC trimers bind H+ IEA Caenorhabditis elegans 15378 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 15378 R-CEL-9705713 https://reactome.org/PathwayBrowser/#/R-CEL-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 15378 R-CEL-9705714 https://reactome.org/PathwayBrowser/#/R-CEL-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 15378 R-CEL-9709098 https://reactome.org/PathwayBrowser/#/R-CEL-9709098 DHFR dimer reduces FOLA to DHF IEA Caenorhabditis elegans 15378 R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 15378 R-CEL-9727349 https://reactome.org/PathwayBrowser/#/R-CEL-9727349 XDH dehydrogenates xanthine to form urate IEA Caenorhabditis elegans 15378 R-CEL-9731661 https://reactome.org/PathwayBrowser/#/R-CEL-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Caenorhabditis elegans 15378 R-CEL-9748945 https://reactome.org/PathwayBrowser/#/R-CEL-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Caenorhabditis elegans 15378 R-CEL-9748957 https://reactome.org/PathwayBrowser/#/R-CEL-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Caenorhabditis elegans 15378 R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 15378 R-CEL-9749609 https://reactome.org/PathwayBrowser/#/R-CEL-9749609 BCHE hydrolyzes ASA- IEA Caenorhabditis elegans 15378 R-CEL-9749647 https://reactome.org/PathwayBrowser/#/R-CEL-9749647 CES2 hydrolyzes ASA- IEA Caenorhabditis elegans 15378 R-CEL-9749792 https://reactome.org/PathwayBrowser/#/R-CEL-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Caenorhabditis elegans 15378 R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans 15378 R-CEL-9755937 https://reactome.org/PathwayBrowser/#/R-CEL-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Caenorhabditis elegans 15378 R-CEL-9756177 https://reactome.org/PathwayBrowser/#/R-CEL-9756177 PON1,3 hydrolyse ATVL to ATV IEA Caenorhabditis elegans 15378 R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 15378 R-CEL-9758682 https://reactome.org/PathwayBrowser/#/R-CEL-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Caenorhabditis elegans 15378 R-CEL-9759549 https://reactome.org/PathwayBrowser/#/R-CEL-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Caenorhabditis elegans 15378 R-CEL-977348 https://reactome.org/PathwayBrowser/#/R-CEL-977348 PHGDH tetramer dehydrogenates 3PG IEA Caenorhabditis elegans 15378 R-CEL-9794270 https://reactome.org/PathwayBrowser/#/R-CEL-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Caenorhabditis elegans 15378 R-CEL-9837337 https://reactome.org/PathwayBrowser/#/R-CEL-9837337 DCAKD phosphorylates DP-CoA IEA Caenorhabditis elegans 15378 R-CEL-9843721 https://reactome.org/PathwayBrowser/#/R-CEL-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Caenorhabditis elegans 15378 R-CEL-9845516 https://reactome.org/PathwayBrowser/#/R-CEL-9845516 B3GALT4 transfers Gal to gangliosides IEA Caenorhabditis elegans 15378 R-CEL-9846332 https://reactome.org/PathwayBrowser/#/R-CEL-9846332 FUT1,2 transfer fucose to gangliosides IEA Caenorhabditis elegans 15378 R-CEL-9853499 https://reactome.org/PathwayBrowser/#/R-CEL-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 15378 R-CEL-9854415 https://reactome.org/PathwayBrowser/#/R-CEL-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Caenorhabditis elegans 15378 R-CEL-9856871 https://reactome.org/PathwayBrowser/#/R-CEL-9856871 MDH1 reduces OA IEA Caenorhabditis elegans 15378 R-CEL-9861616 https://reactome.org/PathwayBrowser/#/R-CEL-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 15378 R-CEL-9861660 https://reactome.org/PathwayBrowser/#/R-CEL-9861660 ME1 tetramer decarboxylates OA to PYR IEA Caenorhabditis elegans 15378 R-CEL-9861734 https://reactome.org/PathwayBrowser/#/R-CEL-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Caenorhabditis elegans 15378 R-CFA-109343 https://reactome.org/PathwayBrowser/#/R-CFA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Canis familiaris 15378 R-CFA-111524 https://reactome.org/PathwayBrowser/#/R-CFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Canis familiaris 15378 R-CFA-1222376 https://reactome.org/PathwayBrowser/#/R-CFA-1222376 NOX2 generates superoxide from oxygen IEA Canis familiaris 15378 R-CFA-1222516 https://reactome.org/PathwayBrowser/#/R-CFA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Canis familiaris 15378 R-CFA-1236967 https://reactome.org/PathwayBrowser/#/R-CFA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Canis familiaris 15378 R-CFA-1237045 https://reactome.org/PathwayBrowser/#/R-CFA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Canis familiaris 15378 R-CFA-1237047 https://reactome.org/PathwayBrowser/#/R-CFA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Canis familiaris 15378 R-CFA-1237059 https://reactome.org/PathwayBrowser/#/R-CFA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Canis familiaris 15378 R-CFA-1237081 https://reactome.org/PathwayBrowser/#/R-CFA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Canis familiaris 15378 R-CFA-1237129 https://reactome.org/PathwayBrowser/#/R-CFA-1237129 Acireductone is created IEA Canis familiaris 15378 R-CFA-1237325 https://reactome.org/PathwayBrowser/#/R-CFA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Canis familiaris 15378 R-CFA-1247668 https://reactome.org/PathwayBrowser/#/R-CFA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Canis familiaris 15378 R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 15378 R-CFA-140359 https://reactome.org/PathwayBrowser/#/R-CFA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Canis familiaris 15378 R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 15378 R-CFA-1475017 https://reactome.org/PathwayBrowser/#/R-CFA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Canis familiaris 15378 R-CFA-1475022 https://reactome.org/PathwayBrowser/#/R-CFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Canis familiaris 15378 R-CFA-1475025 https://reactome.org/PathwayBrowser/#/R-CFA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Canis familiaris 15378 R-CFA-1475026 https://reactome.org/PathwayBrowser/#/R-CFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Canis familiaris 15378 R-CFA-1475028 https://reactome.org/PathwayBrowser/#/R-CFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Canis familiaris 15378 R-CFA-1475032 https://reactome.org/PathwayBrowser/#/R-CFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Canis familiaris 15378 R-CFA-1475435 https://reactome.org/PathwayBrowser/#/R-CFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Canis familiaris 15378 R-CFA-1475436 https://reactome.org/PathwayBrowser/#/R-CFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Canis familiaris 15378 R-CFA-1497869 https://reactome.org/PathwayBrowser/#/R-CFA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Canis familiaris 15378 R-CFA-1562626 https://reactome.org/PathwayBrowser/#/R-CFA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Canis familiaris 15378 R-CFA-156526 https://reactome.org/PathwayBrowser/#/R-CFA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Canis familiaris 15378 R-CFA-158609 https://reactome.org/PathwayBrowser/#/R-CFA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Canis familiaris 15378 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 15378 R-CFA-1605797 https://reactome.org/PathwayBrowser/#/R-CFA-1605797 SMPD1 hydrolyzes SPHM IEA Canis familiaris 15378 R-CFA-1606273 https://reactome.org/PathwayBrowser/#/R-CFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Canis familiaris 15378 R-CFA-1606288 https://reactome.org/PathwayBrowser/#/R-CFA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Canis familiaris 15378 R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 15378 R-CFA-1614362 https://reactome.org/PathwayBrowser/#/R-CFA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Canis familiaris 15378 R-CFA-1614605 https://reactome.org/PathwayBrowser/#/R-CFA-1614605 Persulfide sulfur is dioxygenated IEA Canis familiaris 15378 R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 15378 R-CFA-163217 https://reactome.org/PathwayBrowser/#/R-CFA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Canis familiaris 15378 R-CFA-1638104 https://reactome.org/PathwayBrowser/#/R-CFA-1638104 UGCG transfers glucose to ceramide IEA Canis familiaris 15378 R-CFA-1638845 https://reactome.org/PathwayBrowser/#/R-CFA-1638845 CERK phosphorylates CERA to form C1P IEA Canis familiaris 15378 R-CFA-1640164 https://reactome.org/PathwayBrowser/#/R-CFA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Canis familiaris 15378 R-CFA-164834 https://reactome.org/PathwayBrowser/#/R-CFA-164834 Enzyme-bound ATP is released IEA Canis familiaris 15378 R-CFA-1655453 https://reactome.org/PathwayBrowser/#/R-CFA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Canis familiaris 15378 R-CFA-1655879 https://reactome.org/PathwayBrowser/#/R-CFA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Canis familiaris 15378 R-CFA-1678920 https://reactome.org/PathwayBrowser/#/R-CFA-1678920 TLR processing at low pH IEA Canis familiaris 15378 R-CFA-170026 https://reactome.org/PathwayBrowser/#/R-CFA-170026 Protons are translocated from the intermembrane space to the matrix IEA Canis familiaris 15378 R-CFA-173597 https://reactome.org/PathwayBrowser/#/R-CFA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Canis familiaris 15378 R-CFA-174389 https://reactome.org/PathwayBrowser/#/R-CFA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Canis familiaris 15378 R-CFA-174392 https://reactome.org/PathwayBrowser/#/R-CFA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Canis familiaris 15378 R-CFA-174438 https://reactome.org/PathwayBrowser/#/R-CFA-174438 Formation of the Flap Intermediate on the C-strand IEA Canis familiaris 15378 R-CFA-189421 https://reactome.org/PathwayBrowser/#/R-CFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Canis familiaris 15378 R-CFA-189425 https://reactome.org/PathwayBrowser/#/R-CFA-189425 UROD decarboxylates URO3 to COPRO3 IEA Canis familiaris 15378 R-CFA-189439 https://reactome.org/PathwayBrowser/#/R-CFA-189439 ALAD condenses 2 dALAs to form PBG IEA Canis familiaris 15378 R-CFA-189442 https://reactome.org/PathwayBrowser/#/R-CFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Canis familiaris 15378 R-CFA-189465 https://reactome.org/PathwayBrowser/#/R-CFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Canis familiaris 15378 R-CFA-190182 https://reactome.org/PathwayBrowser/#/R-CFA-190182 UROD decarboxylates URO1 to COPRO1 IEA Canis familiaris 15378 R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 15378 R-CFA-191323 https://reactome.org/PathwayBrowser/#/R-CFA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Canis familiaris 15378 R-CFA-191352 https://reactome.org/PathwayBrowser/#/R-CFA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Canis familiaris 15378 R-CFA-191402 https://reactome.org/PathwayBrowser/#/R-CFA-191402 Reduction of presqualene diphosphate to form squalene IEA Canis familiaris 15378 R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 15378 R-CFA-191999 https://reactome.org/PathwayBrowser/#/R-CFA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Canis familiaris 15378 R-CFA-192033 https://reactome.org/PathwayBrowser/#/R-CFA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Canis familiaris 15378 R-CFA-192042 https://reactome.org/PathwayBrowser/#/R-CFA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 15378 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 15378 R-CFA-192054 https://reactome.org/PathwayBrowser/#/R-CFA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Canis familiaris 15378 R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 15378 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 15378 R-CFA-192067 https://reactome.org/PathwayBrowser/#/R-CFA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Canis familiaris 15378 R-CFA-192097 https://reactome.org/PathwayBrowser/#/R-CFA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Canis familiaris 15378 R-CFA-192123 https://reactome.org/PathwayBrowser/#/R-CFA-192123 CYP27A1 27-hydroxylates CHOL IEA Canis familiaris 15378 R-CFA-192157 https://reactome.org/PathwayBrowser/#/R-CFA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Canis familiaris 15378 R-CFA-192178 https://reactome.org/PathwayBrowser/#/R-CFA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Canis familiaris 15378 R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 15378 R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 15378 R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 15378 R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 15378 R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 15378 R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 15378 R-CFA-193073 https://reactome.org/PathwayBrowser/#/R-CFA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Canis familiaris 15378 R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 15378 R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 15378 R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 15378 R-CFA-193393 https://reactome.org/PathwayBrowser/#/R-CFA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Canis familiaris 15378 R-CFA-193455 https://reactome.org/PathwayBrowser/#/R-CFA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 15378 R-CFA-193460 https://reactome.org/PathwayBrowser/#/R-CFA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Canis familiaris 15378 R-CFA-193497 https://reactome.org/PathwayBrowser/#/R-CFA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Canis familiaris 15378 R-CFA-193508 https://reactome.org/PathwayBrowser/#/R-CFA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 15378 R-CFA-193709 https://reactome.org/PathwayBrowser/#/R-CFA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Canis familiaris 15378 R-CFA-193713 https://reactome.org/PathwayBrowser/#/R-CFA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Canis familiaris 15378 R-CFA-193719 https://reactome.org/PathwayBrowser/#/R-CFA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 15378 R-CFA-193737 https://reactome.org/PathwayBrowser/#/R-CFA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Canis familiaris 15378 R-CFA-193746 https://reactome.org/PathwayBrowser/#/R-CFA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Canis familiaris 15378 R-CFA-193755 https://reactome.org/PathwayBrowser/#/R-CFA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Canis familiaris 15378 R-CFA-193780 https://reactome.org/PathwayBrowser/#/R-CFA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Canis familiaris 15378 R-CFA-193787 https://reactome.org/PathwayBrowser/#/R-CFA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Canis familiaris 15378 R-CFA-193789 https://reactome.org/PathwayBrowser/#/R-CFA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Canis familiaris 15378 R-CFA-193792 https://reactome.org/PathwayBrowser/#/R-CFA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Canis familiaris 15378 R-CFA-193816 https://reactome.org/PathwayBrowser/#/R-CFA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Canis familiaris 15378 R-CFA-193821 https://reactome.org/PathwayBrowser/#/R-CFA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Canis familiaris 15378 R-CFA-193824 https://reactome.org/PathwayBrowser/#/R-CFA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Canis familiaris 15378 R-CFA-193845 https://reactome.org/PathwayBrowser/#/R-CFA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Canis familiaris 15378 R-CFA-193964 https://reactome.org/PathwayBrowser/#/R-CFA-193964 CYP21A2 21-hydroxylates PROG IEA Canis familiaris 15378 R-CFA-193965 https://reactome.org/PathwayBrowser/#/R-CFA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Canis familiaris 15378 R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 15378 R-CFA-193995 https://reactome.org/PathwayBrowser/#/R-CFA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Canis familiaris 15378 R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 15378 R-CFA-194017 https://reactome.org/PathwayBrowser/#/R-CFA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Canis familiaris 15378 R-CFA-194023 https://reactome.org/PathwayBrowser/#/R-CFA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Canis familiaris 15378 R-CFA-194632 https://reactome.org/PathwayBrowser/#/R-CFA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Canis familiaris 15378 R-CFA-194641 https://reactome.org/PathwayBrowser/#/R-CFA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15378 R-CFA-194642 https://reactome.org/PathwayBrowser/#/R-CFA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Canis familiaris 15378 R-CFA-194669 https://reactome.org/PathwayBrowser/#/R-CFA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15378 R-CFA-194674 https://reactome.org/PathwayBrowser/#/R-CFA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Canis familiaris 15378 R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 15378 R-CFA-194689 https://reactome.org/PathwayBrowser/#/R-CFA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15378 R-CFA-194698 https://reactome.org/PathwayBrowser/#/R-CFA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Canis familiaris 15378 R-CFA-194718 https://reactome.org/PathwayBrowser/#/R-CFA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Canis familiaris 15378 R-CFA-195664 https://reactome.org/PathwayBrowser/#/R-CFA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Canis familiaris 15378 R-CFA-196060 https://reactome.org/PathwayBrowser/#/R-CFA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Canis familiaris 15378 R-CFA-196350 https://reactome.org/PathwayBrowser/#/R-CFA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Canis familiaris 15378 R-CFA-196372 https://reactome.org/PathwayBrowser/#/R-CFA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Canis familiaris 15378 R-CFA-196402 https://reactome.org/PathwayBrowser/#/R-CFA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Canis familiaris 15378 R-CFA-196417 https://reactome.org/PathwayBrowser/#/R-CFA-196417 Reduction of desmosterol to cholesterol IEA Canis familiaris 15378 R-CFA-196753 https://reactome.org/PathwayBrowser/#/R-CFA-196753 2xPPCS ligates PPanK with Cys IEA Canis familiaris 15378 R-CFA-196754 https://reactome.org/PathwayBrowser/#/R-CFA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Canis familiaris 15378 R-CFA-196773 https://reactome.org/PathwayBrowser/#/R-CFA-196773 COASY phosphorylates DP-CoA IEA Canis familiaris 15378 R-CFA-196840 https://reactome.org/PathwayBrowser/#/R-CFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Canis familiaris 15378 R-CFA-196857 https://reactome.org/PathwayBrowser/#/R-CFA-196857 PANK2 phosphorylates PanK IEA Canis familiaris 15378 R-CFA-196929 https://reactome.org/PathwayBrowser/#/R-CFA-196929 FLAD1 phosphorylates FMN IEA Canis familiaris 15378 R-CFA-196955 https://reactome.org/PathwayBrowser/#/R-CFA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Canis familiaris 15378 R-CFA-196964 https://reactome.org/PathwayBrowser/#/R-CFA-196964 RFK:Mg2+ phosphorylates RIB IEA Canis familiaris 15378 R-CFA-197186 https://reactome.org/PathwayBrowser/#/R-CFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Canis familiaris 15378 R-CFA-197268 https://reactome.org/PathwayBrowser/#/R-CFA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Canis familiaris 15378 R-CFA-197963 https://reactome.org/PathwayBrowser/#/R-CFA-197963 DHFR2 reduces FOLA to DHF IEA Canis familiaris 15378 R-CFA-197972 https://reactome.org/PathwayBrowser/#/R-CFA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Canis familiaris 15378 R-CFA-198824 https://reactome.org/PathwayBrowser/#/R-CFA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Canis familiaris 15378 R-CFA-199203 https://reactome.org/PathwayBrowser/#/R-CFA-199203 PANK1/3 phosphorylate PanK IEA Canis familiaris 15378 R-CFA-200644 https://reactome.org/PathwayBrowser/#/R-CFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Canis familiaris 15378 R-CFA-200676 https://reactome.org/PathwayBrowser/#/R-CFA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Canis familiaris 15378 R-CFA-200718 https://reactome.org/PathwayBrowser/#/R-CFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Canis familiaris 15378 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 15378 R-CFA-204617 https://reactome.org/PathwayBrowser/#/R-CFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Canis familiaris 15378 R-CFA-204647 https://reactome.org/PathwayBrowser/#/R-CFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Canis familiaris 15378 R-CFA-204662 https://reactome.org/PathwayBrowser/#/R-CFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Canis familiaris 15378 R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 15378 R-CFA-209772 https://reactome.org/PathwayBrowser/#/R-CFA-209772 Thyroxine is deiodinated to triiodothyronine IEA Canis familiaris 15378 R-CFA-209821 https://reactome.org/PathwayBrowser/#/R-CFA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Canis familiaris 15378 R-CFA-209845 https://reactome.org/PathwayBrowser/#/R-CFA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Canis familiaris 15378 R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 15378 R-CFA-209903 https://reactome.org/PathwayBrowser/#/R-CFA-209903 Noradrenaline is converted to adrenaline IEA Canis familiaris 15378 R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 15378 R-CFA-210404 https://reactome.org/PathwayBrowser/#/R-CFA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Canis familiaris 15378 R-CFA-211873 https://reactome.org/PathwayBrowser/#/R-CFA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Canis familiaris 15378 R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 15378 R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 15378 R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 15378 R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 15378 R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 15378 R-CFA-211923 https://reactome.org/PathwayBrowser/#/R-CFA-211923 CYP26C1 4-hydroxylates 9cRA IEA Canis familiaris 15378 R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 15378 R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 15378 R-CFA-211950 https://reactome.org/PathwayBrowser/#/R-CFA-211950 CYP24A1 24-hydroxylates CTL IEA Canis familiaris 15378 R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 15378 R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 15378 R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 15378 R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 15378 R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 15378 R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 15378 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 15378 R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 15378 R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 15378 R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 15378 R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 15378 R-CFA-2161187 https://reactome.org/PathwayBrowser/#/R-CFA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Canis familiaris 15378 R-CFA-2161651 https://reactome.org/PathwayBrowser/#/R-CFA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Canis familiaris 15378 R-CFA-2161745 https://reactome.org/PathwayBrowser/#/R-CFA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15378 R-CFA-2161779 https://reactome.org/PathwayBrowser/#/R-CFA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Canis familiaris 15378 R-CFA-2161792 https://reactome.org/PathwayBrowser/#/R-CFA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15378 R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Canis familiaris 15378 R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 15378 R-CFA-2161890 https://reactome.org/PathwayBrowser/#/R-CFA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Canis familiaris 15378 R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Canis familiaris 15378 R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 15378 R-CFA-2161951 https://reactome.org/PathwayBrowser/#/R-CFA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Canis familiaris 15378 R-CFA-2162078 https://reactome.org/PathwayBrowser/#/R-CFA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Canis familiaris 15378 R-CFA-2162186 https://reactome.org/PathwayBrowser/#/R-CFA-2162186 COQ3 methylates DeMQ10H2 IEA Canis familiaris 15378 R-CFA-2162188 https://reactome.org/PathwayBrowser/#/R-CFA-2162188 COQ5 methylates MDMQ10H2 IEA Canis familiaris 15378 R-CFA-2162193 https://reactome.org/PathwayBrowser/#/R-CFA-2162193 COQ3 methylates DHDB IEA Canis familiaris 15378 R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 15378 R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 15378 R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 15378 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 15378 R-CFA-2395512 https://reactome.org/PathwayBrowser/#/R-CFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Canis familiaris 15378 R-CFA-2395517 https://reactome.org/PathwayBrowser/#/R-CFA-2395517 NADPH transfers electrons to FDXR IEA Canis familiaris 15378 R-CFA-2395818 https://reactome.org/PathwayBrowser/#/R-CFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Canis familiaris 15378 R-CFA-2395849 https://reactome.org/PathwayBrowser/#/R-CFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 15378 R-CFA-2395869 https://reactome.org/PathwayBrowser/#/R-CFA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 15378 R-CFA-2395872 https://reactome.org/PathwayBrowser/#/R-CFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Canis familiaris 15378 R-CFA-2395873 https://reactome.org/PathwayBrowser/#/R-CFA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Canis familiaris 15378 R-CFA-2395876 https://reactome.org/PathwayBrowser/#/R-CFA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 15378 R-CFA-2395879 https://reactome.org/PathwayBrowser/#/R-CFA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 15378 R-CFA-2395965 https://reactome.org/PathwayBrowser/#/R-CFA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Canis familiaris 15378 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 15378 R-CFA-2454081 https://reactome.org/PathwayBrowser/#/R-CFA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Canis familiaris 15378 R-CFA-2464822 https://reactome.org/PathwayBrowser/#/R-CFA-2464822 RDH12 reduces atRAL to atROL IEA Canis familiaris 15378 R-CFA-2465940 https://reactome.org/PathwayBrowser/#/R-CFA-2465940 atRAL is reduced to atROL IEA Canis familiaris 15378 R-CFA-2509793 https://reactome.org/PathwayBrowser/#/R-CFA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Canis familiaris 15378 R-CFA-2509816 https://reactome.org/PathwayBrowser/#/R-CFA-2509816 NUDT16 hydrolyses IDP to IMP IEA Canis familiaris 15378 R-CFA-2509827 https://reactome.org/PathwayBrowser/#/R-CFA-2509827 ITPA hydrolyses ITP to IMP IEA Canis familiaris 15378 R-CFA-2509831 https://reactome.org/PathwayBrowser/#/R-CFA-2509831 ITPA hydrolyses XTP to XMP IEA Canis familiaris 15378 R-CFA-2509838 https://reactome.org/PathwayBrowser/#/R-CFA-2509838 ITPA hydrolyses dITP to dIMP IEA Canis familiaris 15378 R-CFA-2534378 https://reactome.org/PathwayBrowser/#/R-CFA-2534378 Hv1 Mediated H+ Permeability IEA Canis familiaris 15378 R-CFA-264615 https://reactome.org/PathwayBrowser/#/R-CFA-264615 Loading of acetylcholine in synaptic vesicles IEA Canis familiaris 15378 R-CFA-2671885 https://reactome.org/PathwayBrowser/#/R-CFA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Canis familiaris 15378 R-CFA-2730692 https://reactome.org/PathwayBrowser/#/R-CFA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Canis familiaris 15378 R-CFA-2730959 https://reactome.org/PathwayBrowser/#/R-CFA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Canis familiaris 15378 R-CFA-2872444 https://reactome.org/PathwayBrowser/#/R-CFA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Canis familiaris 15378 R-CFA-2889070 https://reactome.org/PathwayBrowser/#/R-CFA-2889070 SLC9B2 exchanges Na+ for H+ IEA Canis familiaris 15378 R-CFA-3095889 https://reactome.org/PathwayBrowser/#/R-CFA-3095889 MMACHC dealkylates RCbl IEA Canis familiaris 15378 R-CFA-3149518 https://reactome.org/PathwayBrowser/#/R-CFA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Canis familiaris 15378 R-CFA-3149519 https://reactome.org/PathwayBrowser/#/R-CFA-3149519 MMACHC decyanates CNCbl IEA Canis familiaris 15378 R-CFA-3159253 https://reactome.org/PathwayBrowser/#/R-CFA-3159253 MMAB adenosylates cob(I)alamin IEA Canis familiaris 15378 R-CFA-3299680 https://reactome.org/PathwayBrowser/#/R-CFA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Canis familiaris 15378 R-CFA-3299682 https://reactome.org/PathwayBrowser/#/R-CFA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Canis familiaris 15378 R-CFA-3299691 https://reactome.org/PathwayBrowser/#/R-CFA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Canis familiaris 15378 R-CFA-3323079 https://reactome.org/PathwayBrowser/#/R-CFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 15378 R-CFA-350901 https://reactome.org/PathwayBrowser/#/R-CFA-350901 Iodide is organified IEA Canis familiaris 15378 R-CFA-352174 https://reactome.org/PathwayBrowser/#/R-CFA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Canis familiaris 15378 R-CFA-352182 https://reactome.org/PathwayBrowser/#/R-CFA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Canis familiaris 15378 R-CFA-372448 https://reactome.org/PathwayBrowser/#/R-CFA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Canis familiaris 15378 R-CFA-373867 https://reactome.org/PathwayBrowser/#/R-CFA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-CFA-373875 https://reactome.org/PathwayBrowser/#/R-CFA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Canis familiaris 15378 R-CFA-375405 https://reactome.org/PathwayBrowser/#/R-CFA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-CFA-375417 https://reactome.org/PathwayBrowser/#/R-CFA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Canis familiaris 15378 R-CFA-3777112 https://reactome.org/PathwayBrowser/#/R-CFA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Canis familiaris 15378 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15378 R-CFA-380608 https://reactome.org/PathwayBrowser/#/R-CFA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Canis familiaris 15378 R-CFA-389540 https://reactome.org/PathwayBrowser/#/R-CFA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 15378 R-CFA-389550 https://reactome.org/PathwayBrowser/#/R-CFA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 15378 R-CFA-389609 https://reactome.org/PathwayBrowser/#/R-CFA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Canis familiaris 15378 R-CFA-389826 https://reactome.org/PathwayBrowser/#/R-CFA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Canis familiaris 15378 R-CFA-389995 https://reactome.org/PathwayBrowser/#/R-CFA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Canis familiaris 15378 R-CFA-390251 https://reactome.org/PathwayBrowser/#/R-CFA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 15378 R-CFA-390425 https://reactome.org/PathwayBrowser/#/R-CFA-390425 FAR1 reduces PalmCoA to HXOL IEA Canis familiaris 15378 R-CFA-390438 https://reactome.org/PathwayBrowser/#/R-CFA-390438 FAR2 reduces PalmCoA to HXOL IEA Canis familiaris 15378 R-CFA-418365 https://reactome.org/PathwayBrowser/#/R-CFA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Canis familiaris 15378 R-CFA-425577 https://reactome.org/PathwayBrowser/#/R-CFA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Canis familiaris 15378 R-CFA-425965 https://reactome.org/PathwayBrowser/#/R-CFA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Canis familiaris 15378 R-CFA-425983 https://reactome.org/PathwayBrowser/#/R-CFA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Canis familiaris 15378 R-CFA-425994 https://reactome.org/PathwayBrowser/#/R-CFA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Canis familiaris 15378 R-CFA-426015 https://reactome.org/PathwayBrowser/#/R-CFA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Canis familiaris 15378 R-CFA-426043 https://reactome.org/PathwayBrowser/#/R-CFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Canis familiaris 15378 R-CFA-427555 https://reactome.org/PathwayBrowser/#/R-CFA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-CFA-427910 https://reactome.org/PathwayBrowser/#/R-CFA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Canis familiaris 15378 R-CFA-427998 https://reactome.org/PathwayBrowser/#/R-CFA-427998 Proton-coupled di- and tri-peptide cotransport IEA Canis familiaris 15378 R-CFA-428007 https://reactome.org/PathwayBrowser/#/R-CFA-428007 Proton-coupled histidine and di-peptide cotransport IEA Canis familiaris 15378 R-CFA-428015 https://reactome.org/PathwayBrowser/#/R-CFA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Canis familiaris 15378 R-CFA-428052 https://reactome.org/PathwayBrowser/#/R-CFA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Canis familiaris 15378 R-CFA-428123 https://reactome.org/PathwayBrowser/#/R-CFA-428123 KDSR reduces 3-ketosphingoid IEA Canis familiaris 15378 R-CFA-428127 https://reactome.org/PathwayBrowser/#/R-CFA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Canis familiaris 15378 R-CFA-428185 https://reactome.org/PathwayBrowser/#/R-CFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Canis familiaris 15378 R-CFA-428259 https://reactome.org/PathwayBrowser/#/R-CFA-428259 DEGS1 dehydrogenates dihydroceramide IEA Canis familiaris 15378 R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 15378 R-CFA-428273 https://reactome.org/PathwayBrowser/#/R-CFA-428273 SPHK1 phosphorylates sphingoid IEA Canis familiaris 15378 R-CFA-428585 https://reactome.org/PathwayBrowser/#/R-CFA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Canis familiaris 15378 R-CFA-428625 https://reactome.org/PathwayBrowser/#/R-CFA-428625 Vesicular inhibitory amino acid transport IEA Canis familiaris 15378 R-CFA-429101 https://reactome.org/PathwayBrowser/#/R-CFA-429101 HMIT co-transports myo-inositol with a proton IEA Canis familiaris 15378 R-CFA-429157 https://reactome.org/PathwayBrowser/#/R-CFA-429157 ABCC4 accumulation of dense granule contents IEA Canis familiaris 15378 R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-CFA-434650 https://reactome.org/PathwayBrowser/#/R-CFA-434650 MATEs mediate extrusion of xenobiotics IEA Canis familiaris 15378 R-CFA-435171 https://reactome.org/PathwayBrowser/#/R-CFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Canis familiaris 15378 R-CFA-435349 https://reactome.org/PathwayBrowser/#/R-CFA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-CFA-444393 https://reactome.org/PathwayBrowser/#/R-CFA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Canis familiaris 15378 R-CFA-444419 https://reactome.org/PathwayBrowser/#/R-CFA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Canis familiaris 15378 R-CFA-444731 https://reactome.org/PathwayBrowser/#/R-CFA-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Canis familiaris 15378 R-CFA-446277 https://reactome.org/PathwayBrowser/#/R-CFA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Canis familiaris 15378 R-CFA-446278 https://reactome.org/PathwayBrowser/#/R-CFA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Canis familiaris 15378 R-CFA-450971 https://reactome.org/PathwayBrowser/#/R-CFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Canis familiaris 15378 R-CFA-469659 https://reactome.org/PathwayBrowser/#/R-CFA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Canis familiaris 15378 R-CFA-504054 https://reactome.org/PathwayBrowser/#/R-CFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Canis familiaris 15378 R-CFA-508040 https://reactome.org/PathwayBrowser/#/R-CFA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Canis familiaris 15378 R-CFA-508369 https://reactome.org/PathwayBrowser/#/R-CFA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Canis familiaris 15378 R-CFA-508473 https://reactome.org/PathwayBrowser/#/R-CFA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Canis familiaris 15378 R-CFA-514604 https://reactome.org/PathwayBrowser/#/R-CFA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Canis familiaris 15378 R-CFA-5218841 https://reactome.org/PathwayBrowser/#/R-CFA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Canis familiaris 15378 R-CFA-5340130 https://reactome.org/PathwayBrowser/#/R-CFA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Canis familiaris 15378 R-CFA-5340226 https://reactome.org/PathwayBrowser/#/R-CFA-5340226 CYGB dioxygenates NO IEA Canis familiaris 15378 R-CFA-5362518 https://reactome.org/PathwayBrowser/#/R-CFA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Canis familiaris 15378 R-CFA-5362522 https://reactome.org/PathwayBrowser/#/R-CFA-5362522 ALDHs oxidise atRAL to atRA IEA Canis familiaris 15378 R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 15378 R-CFA-5362564 https://reactome.org/PathwayBrowser/#/R-CFA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Canis familiaris 15378 R-CFA-5362721 https://reactome.org/PathwayBrowser/#/R-CFA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Canis familiaris 15378 R-CFA-5419165 https://reactome.org/PathwayBrowser/#/R-CFA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Canis familiaris 15378 R-CFA-5423637 https://reactome.org/PathwayBrowser/#/R-CFA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Canis familiaris 15378 R-CFA-5423647 https://reactome.org/PathwayBrowser/#/R-CFA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Canis familiaris 15378 R-CFA-5423664 https://reactome.org/PathwayBrowser/#/R-CFA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Canis familiaris 15378 R-CFA-5423672 https://reactome.org/PathwayBrowser/#/R-CFA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Canis familiaris 15378 R-CFA-548818 https://reactome.org/PathwayBrowser/#/R-CFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Canis familiaris 15378 R-CFA-548831 https://reactome.org/PathwayBrowser/#/R-CFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Canis familiaris 15378 R-CFA-5602295 https://reactome.org/PathwayBrowser/#/R-CFA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Canis familiaris 15378 R-CFA-5623643 https://reactome.org/PathwayBrowser/#/R-CFA-5623643 RDH13 reduces atRAL to atROL IEA Canis familiaris 15378 R-CFA-5652172 https://reactome.org/PathwayBrowser/#/R-CFA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Canis familiaris 15378 R-CFA-5652195 https://reactome.org/PathwayBrowser/#/R-CFA-5652195 SORD oxidizes D-sorbitol to Fru IEA Canis familiaris 15378 R-CFA-5661240 https://reactome.org/PathwayBrowser/#/R-CFA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Canis familiaris 15378 R-CFA-5661256 https://reactome.org/PathwayBrowser/#/R-CFA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Canis familiaris 15378 R-CFA-5661290 https://reactome.org/PathwayBrowser/#/R-CFA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Canis familiaris 15378 R-CFA-5662471 https://reactome.org/PathwayBrowser/#/R-CFA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Canis familiaris 15378 R-CFA-5662662 https://reactome.org/PathwayBrowser/#/R-CFA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Canis familiaris 15378 R-CFA-5668629 https://reactome.org/PathwayBrowser/#/R-CFA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Canis familiaris 15378 R-CFA-5668718 https://reactome.org/PathwayBrowser/#/R-CFA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 15378 R-CFA-5668731 https://reactome.org/PathwayBrowser/#/R-CFA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 15378 R-CFA-5678327 https://reactome.org/PathwayBrowser/#/R-CFA-5678327 MIOX oxidises Ins to GlcA IEA Canis familiaris 15378 R-CFA-5690565 https://reactome.org/PathwayBrowser/#/R-CFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15378 R-CFA-5691107 https://reactome.org/PathwayBrowser/#/R-CFA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Canis familiaris 15378 R-CFA-5692237 https://reactome.org/PathwayBrowser/#/R-CFA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Canis familiaris 15378 R-CFA-5692261 https://reactome.org/PathwayBrowser/#/R-CFA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Canis familiaris 15378 R-CFA-5692283 https://reactome.org/PathwayBrowser/#/R-CFA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Canis familiaris 15378 R-CFA-5693347 https://reactome.org/PathwayBrowser/#/R-CFA-5693347 CRYM reduces P2C to PPCA IEA Canis familiaris 15378 R-CFA-5693390 https://reactome.org/PathwayBrowser/#/R-CFA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Canis familiaris 15378 R-CFA-5693681 https://reactome.org/PathwayBrowser/#/R-CFA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Canis familiaris 15378 R-CFA-5693691 https://reactome.org/PathwayBrowser/#/R-CFA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Canis familiaris 15378 R-CFA-5693761 https://reactome.org/PathwayBrowser/#/R-CFA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Canis familiaris 15378 R-CFA-5694018 https://reactome.org/PathwayBrowser/#/R-CFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Canis familiaris 15378 R-CFA-5694462 https://reactome.org/PathwayBrowser/#/R-CFA-5694462 ABHD6,12 hydrolyse 3AG IEA Canis familiaris 15378 R-CFA-5696080 https://reactome.org/PathwayBrowser/#/R-CFA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Canis familiaris 15378 R-CFA-5696091 https://reactome.org/PathwayBrowser/#/R-CFA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Canis familiaris 15378 R-CFA-5696101 https://reactome.org/PathwayBrowser/#/R-CFA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Canis familiaris 15378 R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 15378 R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 15378 R-CFA-5696457 https://reactome.org/PathwayBrowser/#/R-CFA-5696457 BDH2 dehydrogenates 3HBA IEA Canis familiaris 15378 R-CFA-5696838 https://reactome.org/PathwayBrowser/#/R-CFA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Canis familiaris 15378 R-CFA-597628 https://reactome.org/PathwayBrowser/#/R-CFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Canis familiaris 15378 R-CFA-6783221 https://reactome.org/PathwayBrowser/#/R-CFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Canis familiaris 15378 R-CFA-6783939 https://reactome.org/PathwayBrowser/#/R-CFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 15378 R-CFA-6783955 https://reactome.org/PathwayBrowser/#/R-CFA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 15378 R-CFA-6784399 https://reactome.org/PathwayBrowser/#/R-CFA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Canis familiaris 15378 R-CFA-6785933 https://reactome.org/PathwayBrowser/#/R-CFA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Canis familiaris 15378 R-CFA-6786239 https://reactome.org/PathwayBrowser/#/R-CFA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Canis familiaris 15378 R-CFA-6786720 https://reactome.org/PathwayBrowser/#/R-CFA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Canis familiaris 15378 R-CFA-6787642 https://reactome.org/PathwayBrowser/#/R-CFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Canis familiaris 15378 R-CFA-6788999 https://reactome.org/PathwayBrowser/#/R-CFA-6788999 HV1-mediated H+ transfer IEA Canis familiaris 15378 R-CFA-6789031 https://reactome.org/PathwayBrowser/#/R-CFA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 15378 R-CFA-6789092 https://reactome.org/PathwayBrowser/#/R-CFA-6789092 NOX2 generates superoxide anion from oxygen IEA Canis familiaris 15378 R-CFA-6789126 https://reactome.org/PathwayBrowser/#/R-CFA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 15378 R-CFA-6793590 https://reactome.org/PathwayBrowser/#/R-CFA-6793590 LIPT2 transfers octanoyl group to GCSH IEA Canis familiaris 15378 R-CFA-6793591 https://reactome.org/PathwayBrowser/#/R-CFA-6793591 LIAS synthesizes lipoyl-GCSH IEA Canis familiaris 15378 R-CFA-6799495 https://reactome.org/PathwayBrowser/#/R-CFA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Canis familiaris 15378 R-CFA-6799722 https://reactome.org/PathwayBrowser/#/R-CFA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Canis familiaris 15378 R-CFA-6801342 https://reactome.org/PathwayBrowser/#/R-CFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Canis familiaris 15378 R-CFA-6803771 https://reactome.org/PathwayBrowser/#/R-CFA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Canis familiaris 15378 R-CFA-6806647 https://reactome.org/PathwayBrowser/#/R-CFA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 15378 R-CFA-6806831 https://reactome.org/PathwayBrowser/#/R-CFA-6806831 CYB5Rs reduce MetHb to HbA IEA Canis familiaris 15378 R-CFA-6806967 https://reactome.org/PathwayBrowser/#/R-CFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Canis familiaris 15378 R-CFA-6807053 https://reactome.org/PathwayBrowser/#/R-CFA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Canis familiaris 15378 R-CFA-6807055 https://reactome.org/PathwayBrowser/#/R-CFA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Canis familiaris 15378 R-CFA-6807064 https://reactome.org/PathwayBrowser/#/R-CFA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Canis familiaris 15378 R-CFA-6807557 https://reactome.org/PathwayBrowser/#/R-CFA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Canis familiaris 15378 R-CFA-6807826 https://reactome.org/PathwayBrowser/#/R-CFA-6807826 LDHAL6B reduces PYR to LACT IEA Canis familiaris 15378 R-CFA-6808464 https://reactome.org/PathwayBrowser/#/R-CFA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Canis familiaris 15378 R-CFA-6808487 https://reactome.org/PathwayBrowser/#/R-CFA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 15378 R-CFA-6808496 https://reactome.org/PathwayBrowser/#/R-CFA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 15378 R-CFA-6809264 https://reactome.org/PathwayBrowser/#/R-CFA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 15378 R-CFA-6809287 https://reactome.org/PathwayBrowser/#/R-CFA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Canis familiaris 15378 R-CFA-6809810 https://reactome.org/PathwayBrowser/#/R-CFA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Canis familiaris 15378 R-CFA-6813749 https://reactome.org/PathwayBrowser/#/R-CFA-6813749 ALDH1A1 oxidises GA to DGA IEA Canis familiaris 15378 R-CFA-6814153 https://reactome.org/PathwayBrowser/#/R-CFA-6814153 ADO oxidises 2AET to HTAU IEA Canis familiaris 15378 R-CFA-70377 https://reactome.org/PathwayBrowser/#/R-CFA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Canis familiaris 15378 R-CFA-70420 https://reactome.org/PathwayBrowser/#/R-CFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Canis familiaris 15378 R-CFA-70449 https://reactome.org/PathwayBrowser/#/R-CFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Canis familiaris 15378 R-CFA-70467 https://reactome.org/PathwayBrowser/#/R-CFA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Canis familiaris 15378 R-CFA-70482 https://reactome.org/PathwayBrowser/#/R-CFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Canis familiaris 15378 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 15378 R-CFA-70510 https://reactome.org/PathwayBrowser/#/R-CFA-70510 LDH tetramer oxidises LACT to PYR IEA Canis familiaris 15378 R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Canis familiaris 15378 R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Canis familiaris 15378 R-CFA-70664 https://reactome.org/PathwayBrowser/#/R-CFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 15378 R-CFA-70670 https://reactome.org/PathwayBrowser/#/R-CFA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Canis familiaris 15378 R-CFA-70679 https://reactome.org/PathwayBrowser/#/R-CFA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Canis familiaris 15378 R-CFA-70837 https://reactome.org/PathwayBrowser/#/R-CFA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Canis familiaris 15378 R-CFA-70885 https://reactome.org/PathwayBrowser/#/R-CFA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Canis familiaris 15378 R-CFA-70893 https://reactome.org/PathwayBrowser/#/R-CFA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Canis familiaris 15378 R-CFA-70906 https://reactome.org/PathwayBrowser/#/R-CFA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Canis familiaris 15378 R-CFA-70938 https://reactome.org/PathwayBrowser/#/R-CFA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Canis familiaris 15378 R-CFA-70940 https://reactome.org/PathwayBrowser/#/R-CFA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Canis familiaris 15378 R-CFA-70941 https://reactome.org/PathwayBrowser/#/R-CFA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Canis familiaris 15378 R-CFA-70975 https://reactome.org/PathwayBrowser/#/R-CFA-70975 CS acetylates OA to citrate IEA Canis familiaris 15378 R-CFA-70979 https://reactome.org/PathwayBrowser/#/R-CFA-70979 MDH2 dimer dehydrogenates MAL IEA Canis familiaris 15378 R-CFA-71130 https://reactome.org/PathwayBrowser/#/R-CFA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Canis familiaris 15378 R-CFA-71164 https://reactome.org/PathwayBrowser/#/R-CFA-71164 HGD dioxygenates homogentisate IEA Canis familiaris 15378 R-CFA-71181 https://reactome.org/PathwayBrowser/#/R-CFA-71181 FAH cleaves 4FAA IEA Canis familiaris 15378 R-CFA-71200 https://reactome.org/PathwayBrowser/#/R-CFA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Canis familiaris 15378 R-CFA-71260 https://reactome.org/PathwayBrowser/#/R-CFA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Canis familiaris 15378 R-CFA-71286 https://reactome.org/PathwayBrowser/#/R-CFA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Canis familiaris 15378 R-CFA-71299 https://reactome.org/PathwayBrowser/#/R-CFA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Canis familiaris 15378 R-CFA-71401 https://reactome.org/PathwayBrowser/#/R-CFA-71401 OGDH dimer decarboxylates 2-OG IEA Canis familiaris 15378 R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 15378 R-CFA-71682 https://reactome.org/PathwayBrowser/#/R-CFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 15378 R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 15378 R-CFA-71707 https://reactome.org/PathwayBrowser/#/R-CFA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Canis familiaris 15378 R-CFA-71723 https://reactome.org/PathwayBrowser/#/R-CFA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Canis familiaris 15378 R-CFA-71849 https://reactome.org/PathwayBrowser/#/R-CFA-71849 LDH tetramer reduces PYR to LACT IEA Canis familiaris 15378 R-CFA-73564 https://reactome.org/PathwayBrowser/#/R-CFA-73564 UMPS dimer decarboxylates OMP to UMP IEA Canis familiaris 15378 R-CFA-73571 https://reactome.org/PathwayBrowser/#/R-CFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Canis familiaris 15378 R-CFA-73573 https://reactome.org/PathwayBrowser/#/R-CFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Canis familiaris 15378 R-CFA-73577 https://reactome.org/PathwayBrowser/#/R-CFA-73577 CAD hexamer transforms L-Gln to CAP IEA Canis familiaris 15378 R-CFA-73585 https://reactome.org/PathwayBrowser/#/R-CFA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Canis familiaris 15378 R-CFA-73589 https://reactome.org/PathwayBrowser/#/R-CFA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Canis familiaris 15378 R-CFA-73591 https://reactome.org/PathwayBrowser/#/R-CFA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Canis familiaris 15378 R-CFA-73596 https://reactome.org/PathwayBrowser/#/R-CFA-73596 dCMP + H2O => dUMP + NH4+ IEA Canis familiaris 15378 R-CFA-73616 https://reactome.org/PathwayBrowser/#/R-CFA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Canis familiaris 15378 R-CFA-73618 https://reactome.org/PathwayBrowser/#/R-CFA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Canis familiaris 15378 R-CFA-73620 https://reactome.org/PathwayBrowser/#/R-CFA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Canis familiaris 15378 R-CFA-73647 https://reactome.org/PathwayBrowser/#/R-CFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Canis familiaris 15378 R-CFA-73666 https://reactome.org/PathwayBrowser/#/R-CFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Canis familiaris 15378 R-CFA-73792 https://reactome.org/PathwayBrowser/#/R-CFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Canis familiaris 15378 R-CFA-73794 https://reactome.org/PathwayBrowser/#/R-CFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Canis familiaris 15378 R-CFA-73805 https://reactome.org/PathwayBrowser/#/R-CFA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Canis familiaris 15378 R-CFA-73806 https://reactome.org/PathwayBrowser/#/R-CFA-73806 AIR + CO2 => CAIR IEA Canis familiaris 15378 R-CFA-73810 https://reactome.org/PathwayBrowser/#/R-CFA-73810 FGAM + ATP => AIR + ADP + Pi IEA Canis familiaris 15378 R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 15378 R-CFA-73813 https://reactome.org/PathwayBrowser/#/R-CFA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Canis familiaris 15378 R-CFA-73814 https://reactome.org/PathwayBrowser/#/R-CFA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Canis familiaris 15378 R-CFA-73912 https://reactome.org/PathwayBrowser/#/R-CFA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Canis familiaris 15378 R-CFA-73920 https://reactome.org/PathwayBrowser/#/R-CFA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Canis familiaris 15378 R-CFA-74255 https://reactome.org/PathwayBrowser/#/R-CFA-74255 Guanine + H2O => Xanthine + NH4+ IEA Canis familiaris 15378 R-CFA-74723 https://reactome.org/PathwayBrowser/#/R-CFA-74723 Endosome acidification IEA Canis familiaris 15378 R-CFA-74872 https://reactome.org/PathwayBrowser/#/R-CFA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Canis familiaris 15378 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15378 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15378 R-CFA-75872 https://reactome.org/PathwayBrowser/#/R-CFA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Canis familiaris 15378 R-CFA-75883 https://reactome.org/PathwayBrowser/#/R-CFA-75883 DHRS7B reduces GO3P to HXDG3P IEA Canis familiaris 15378 R-CFA-75889 https://reactome.org/PathwayBrowser/#/R-CFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Canis familiaris 15378 R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 15378 R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 15378 R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 15378 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 15378 R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 15378 R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 15378 R-CFA-77254 https://reactome.org/PathwayBrowser/#/R-CFA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Canis familiaris 15378 R-CFA-77283 https://reactome.org/PathwayBrowser/#/R-CFA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Canis familiaris 15378 R-CFA-77303 https://reactome.org/PathwayBrowser/#/R-CFA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Canis familiaris 15378 R-CFA-77312 https://reactome.org/PathwayBrowser/#/R-CFA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Canis familiaris 15378 R-CFA-77323 https://reactome.org/PathwayBrowser/#/R-CFA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Canis familiaris 15378 R-CFA-77331 https://reactome.org/PathwayBrowser/#/R-CFA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Canis familiaris 15378 R-CFA-77342 https://reactome.org/PathwayBrowser/#/R-CFA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Canis familiaris 15378 R-CFA-804969 https://reactome.org/PathwayBrowser/#/R-CFA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Canis familiaris 15378 R-CFA-8847579 https://reactome.org/PathwayBrowser/#/R-CFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15378 R-CFA-8850846 https://reactome.org/PathwayBrowser/#/R-CFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-CFA-8850854 https://reactome.org/PathwayBrowser/#/R-CFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-CFA-8851110 https://reactome.org/PathwayBrowser/#/R-CFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-CFA-8851129 https://reactome.org/PathwayBrowser/#/R-CFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 15378 R-CFA-8862137 https://reactome.org/PathwayBrowser/#/R-CFA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Canis familiaris 15378 R-CFA-8862152 https://reactome.org/PathwayBrowser/#/R-CFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Canis familiaris 15378 R-CFA-8863494 https://reactome.org/PathwayBrowser/#/R-CFA-8863494 ASICs bind STOML3, (STOM) IEA Canis familiaris 15378 R-CFA-8866601 https://reactome.org/PathwayBrowser/#/R-CFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Canis familiaris 15378 R-CFA-8869606 https://reactome.org/PathwayBrowser/#/R-CFA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Canis familiaris 15378 R-CFA-8869633 https://reactome.org/PathwayBrowser/#/R-CFA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Canis familiaris 15378 R-CFA-8870346 https://reactome.org/PathwayBrowser/#/R-CFA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Canis familiaris 15378 R-CFA-8875623 https://reactome.org/PathwayBrowser/#/R-CFA-8875623 SLC25A18,22 import L-Glu, H+ IEA Canis familiaris 15378 R-CFA-8878914 https://reactome.org/PathwayBrowser/#/R-CFA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Canis familiaris 15378 R-CFA-888548 https://reactome.org/PathwayBrowser/#/R-CFA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Canis familiaris 15378 R-CFA-888572 https://reactome.org/PathwayBrowser/#/R-CFA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Canis familiaris 15378 R-CFA-888577 https://reactome.org/PathwayBrowser/#/R-CFA-888577 Synthesis of GABA by GAD2 IEA Canis familiaris 15378 R-CFA-8933635 https://reactome.org/PathwayBrowser/#/R-CFA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Canis familiaris 15378 R-CFA-8936442 https://reactome.org/PathwayBrowser/#/R-CFA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Canis familiaris 15378 R-CFA-8938076 https://reactome.org/PathwayBrowser/#/R-CFA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Canis familiaris 15378 R-CFA-8952873 https://reactome.org/PathwayBrowser/#/R-CFA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Canis familiaris 15378 R-CFA-8954468 https://reactome.org/PathwayBrowser/#/R-CFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Canis familiaris 15378 R-CFA-8955030 https://reactome.org/PathwayBrowser/#/R-CFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Canis familiaris 15378 R-CFA-8955760 https://reactome.org/PathwayBrowser/#/R-CFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Canis familiaris 15378 R-CFA-8956458 https://reactome.org/PathwayBrowser/#/R-CFA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Canis familiaris 15378 R-CFA-8959510 https://reactome.org/PathwayBrowser/#/R-CFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Canis familiaris 15378 R-CFA-8959719 https://reactome.org/PathwayBrowser/#/R-CFA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Canis familiaris 15378 R-CFA-9009950 https://reactome.org/PathwayBrowser/#/R-CFA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Canis familiaris 15378 R-CFA-9011595 https://reactome.org/PathwayBrowser/#/R-CFA-9011595 GSTZ1 dimer dehalogenates DCA IEA Canis familiaris 15378 R-CFA-9012016 https://reactome.org/PathwayBrowser/#/R-CFA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Canis familiaris 15378 R-CFA-9012036 https://reactome.org/PathwayBrowser/#/R-CFA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Canis familiaris 15378 R-CFA-9024993 https://reactome.org/PathwayBrowser/#/R-CFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Canis familiaris 15378 R-CFA-9027043 https://reactome.org/PathwayBrowser/#/R-CFA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Canis familiaris 15378 R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 15378 R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 15378 R-CFA-917811 https://reactome.org/PathwayBrowser/#/R-CFA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Canis familiaris 15378 R-CFA-917841 https://reactome.org/PathwayBrowser/#/R-CFA-917841 Acidification of Tf:TfR1 containing endosome IEA Canis familiaris 15378 R-CFA-917891 https://reactome.org/PathwayBrowser/#/R-CFA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Canis familiaris 15378 R-CFA-917933 https://reactome.org/PathwayBrowser/#/R-CFA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Canis familiaris 15378 R-CFA-917979 https://reactome.org/PathwayBrowser/#/R-CFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Canis familiaris 15378 R-CFA-937311 https://reactome.org/PathwayBrowser/#/R-CFA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Canis familiaris 15378 R-CFA-9620103 https://reactome.org/PathwayBrowser/#/R-CFA-9620103 ALDH2 transforms GTN to NO IEA Canis familiaris 15378 R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-CFA-9650165 https://reactome.org/PathwayBrowser/#/R-CFA-9650165 ASIC trimers bind H+ IEA Canis familiaris 15378 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 15378 R-CFA-9705713 https://reactome.org/PathwayBrowser/#/R-CFA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Canis familiaris 15378 R-CFA-9705714 https://reactome.org/PathwayBrowser/#/R-CFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Canis familiaris 15378 R-CFA-9709098 https://reactome.org/PathwayBrowser/#/R-CFA-9709098 DHFR dimer reduces FOLA to DHF IEA Canis familiaris 15378 R-CFA-9727198 https://reactome.org/PathwayBrowser/#/R-CFA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Canis familiaris 15378 R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 15378 R-CFA-9727349 https://reactome.org/PathwayBrowser/#/R-CFA-9727349 XDH dehydrogenates xanthine to form urate IEA Canis familiaris 15378 R-CFA-9731228 https://reactome.org/PathwayBrowser/#/R-CFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Canis familiaris 15378 R-CFA-9731590 https://reactome.org/PathwayBrowser/#/R-CFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Canis familiaris 15378 R-CFA-9731613 https://reactome.org/PathwayBrowser/#/R-CFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Canis familiaris 15378 R-CFA-9731632 https://reactome.org/PathwayBrowser/#/R-CFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Canis familiaris 15378 R-CFA-9731661 https://reactome.org/PathwayBrowser/#/R-CFA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Canis familiaris 15378 R-CFA-9748945 https://reactome.org/PathwayBrowser/#/R-CFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Canis familiaris 15378 R-CFA-9748957 https://reactome.org/PathwayBrowser/#/R-CFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Canis familiaris 15378 R-CFA-9748979 https://reactome.org/PathwayBrowser/#/R-CFA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Canis familiaris 15378 R-CFA-9748983 https://reactome.org/PathwayBrowser/#/R-CFA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Canis familiaris 15378 R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 15378 R-CFA-9749609 https://reactome.org/PathwayBrowser/#/R-CFA-9749609 BCHE hydrolyzes ASA- IEA Canis familiaris 15378 R-CFA-9749647 https://reactome.org/PathwayBrowser/#/R-CFA-9749647 CES2 hydrolyzes ASA- IEA Canis familiaris 15378 R-CFA-9749792 https://reactome.org/PathwayBrowser/#/R-CFA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Canis familiaris 15378 R-CFA-9753285 https://reactome.org/PathwayBrowser/#/R-CFA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Canis familiaris 15378 R-CFA-9755937 https://reactome.org/PathwayBrowser/#/R-CFA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Canis familiaris 15378 R-CFA-9756138 https://reactome.org/PathwayBrowser/#/R-CFA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Canis familiaris 15378 R-CFA-9756162 https://reactome.org/PathwayBrowser/#/R-CFA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Canis familiaris 15378 R-CFA-9756169 https://reactome.org/PathwayBrowser/#/R-CFA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Canis familiaris 15378 R-CFA-9756177 https://reactome.org/PathwayBrowser/#/R-CFA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Canis familiaris 15378 R-CFA-9756180 https://reactome.org/PathwayBrowser/#/R-CFA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Canis familiaris 15378 R-CFA-9757706 https://reactome.org/PathwayBrowser/#/R-CFA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Canis familiaris 15378 R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 15378 R-CFA-9758674 https://reactome.org/PathwayBrowser/#/R-CFA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Canis familiaris 15378 R-CFA-9759259 https://reactome.org/PathwayBrowser/#/R-CFA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Canis familiaris 15378 R-CFA-9759549 https://reactome.org/PathwayBrowser/#/R-CFA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Canis familiaris 15378 R-CFA-9760094 https://reactome.org/PathwayBrowser/#/R-CFA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Canis familiaris 15378 R-CFA-977348 https://reactome.org/PathwayBrowser/#/R-CFA-977348 PHGDH tetramer dehydrogenates 3PG IEA Canis familiaris 15378 R-CFA-9794270 https://reactome.org/PathwayBrowser/#/R-CFA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Canis familiaris 15378 R-CFA-9837337 https://reactome.org/PathwayBrowser/#/R-CFA-9837337 DCAKD phosphorylates DP-CoA IEA Canis familiaris 15378 R-CFA-9843721 https://reactome.org/PathwayBrowser/#/R-CFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Canis familiaris 15378 R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 15378 R-CFA-9845516 https://reactome.org/PathwayBrowser/#/R-CFA-9845516 B3GALT4 transfers Gal to gangliosides IEA Canis familiaris 15378 R-CFA-9845538 https://reactome.org/PathwayBrowser/#/R-CFA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Canis familiaris 15378 R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 15378 R-CFA-9846305 https://reactome.org/PathwayBrowser/#/R-CFA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Canis familiaris 15378 R-CFA-9846332 https://reactome.org/PathwayBrowser/#/R-CFA-9846332 FUT1,2 transfer fucose to gangliosides IEA Canis familiaris 15378 R-CFA-9846477 https://reactome.org/PathwayBrowser/#/R-CFA-9846477 A4GALT transfers galactose to LacCer IEA Canis familiaris 15378 R-CFA-9851347 https://reactome.org/PathwayBrowser/#/R-CFA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Canis familiaris 15378 R-CFA-9853499 https://reactome.org/PathwayBrowser/#/R-CFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 15378 R-CFA-9854315 https://reactome.org/PathwayBrowser/#/R-CFA-9854315 CSKMT methylates Citrate Synthase IEA Canis familiaris 15378 R-CFA-9854415 https://reactome.org/PathwayBrowser/#/R-CFA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Canis familiaris 15378 R-CFA-9856871 https://reactome.org/PathwayBrowser/#/R-CFA-9856871 MDH1 reduces OA IEA Canis familiaris 15378 R-CFA-9861616 https://reactome.org/PathwayBrowser/#/R-CFA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 15378 R-CFA-9861642 https://reactome.org/PathwayBrowser/#/R-CFA-9861642 NEK1 phosphorylates ME1 IEA Canis familiaris 15378 R-CFA-9861660 https://reactome.org/PathwayBrowser/#/R-CFA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Canis familiaris 15378 R-CFA-9861734 https://reactome.org/PathwayBrowser/#/R-CFA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Canis familiaris 15378 R-DDI-111524 https://reactome.org/PathwayBrowser/#/R-DDI-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Dictyostelium discoideum 15378 R-DDI-1222516 https://reactome.org/PathwayBrowser/#/R-DDI-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Dictyostelium discoideum 15378 R-DDI-1237129 https://reactome.org/PathwayBrowser/#/R-DDI-1237129 Acireductone is created IEA Dictyostelium discoideum 15378 R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 15378 R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 15378 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 15378 R-DDI-1497869 https://reactome.org/PathwayBrowser/#/R-DDI-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Dictyostelium discoideum 15378 R-DDI-156526 https://reactome.org/PathwayBrowser/#/R-DDI-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Dictyostelium discoideum 15378 R-DDI-1605797 https://reactome.org/PathwayBrowser/#/R-DDI-1605797 SMPD1 hydrolyzes SPHM IEA Dictyostelium discoideum 15378 R-DDI-1606273 https://reactome.org/PathwayBrowser/#/R-DDI-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Dictyostelium discoideum 15378 R-DDI-1640164 https://reactome.org/PathwayBrowser/#/R-DDI-1640164 ENPP7 hydrolyzes sphingomyelin IEA Dictyostelium discoideum 15378 R-DDI-164651 https://reactome.org/PathwayBrowser/#/R-DDI-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Dictyostelium discoideum 15378 R-DDI-1655453 https://reactome.org/PathwayBrowser/#/R-DDI-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Dictyostelium discoideum 15378 R-DDI-189421 https://reactome.org/PathwayBrowser/#/R-DDI-189421 CPO transforms COPRO3 to PPGEN9 IEA Dictyostelium discoideum 15378 R-DDI-189425 https://reactome.org/PathwayBrowser/#/R-DDI-189425 UROD decarboxylates URO3 to COPRO3 IEA Dictyostelium discoideum 15378 R-DDI-189439 https://reactome.org/PathwayBrowser/#/R-DDI-189439 ALAD condenses 2 dALAs to form PBG IEA Dictyostelium discoideum 15378 R-DDI-189442 https://reactome.org/PathwayBrowser/#/R-DDI-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Dictyostelium discoideum 15378 R-DDI-189465 https://reactome.org/PathwayBrowser/#/R-DDI-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Dictyostelium discoideum 15378 R-DDI-190182 https://reactome.org/PathwayBrowser/#/R-DDI-190182 UROD decarboxylates URO1 to COPRO1 IEA Dictyostelium discoideum 15378 R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 15378 R-DDI-191323 https://reactome.org/PathwayBrowser/#/R-DDI-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Dictyostelium discoideum 15378 R-DDI-191352 https://reactome.org/PathwayBrowser/#/R-DDI-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Dictyostelium discoideum 15378 R-DDI-191402 https://reactome.org/PathwayBrowser/#/R-DDI-191402 Reduction of presqualene diphosphate to form squalene IEA Dictyostelium discoideum 15378 R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 15378 R-DDI-192033 https://reactome.org/PathwayBrowser/#/R-DDI-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Dictyostelium discoideum 15378 R-DDI-192036 https://reactome.org/PathwayBrowser/#/R-DDI-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Dictyostelium discoideum 15378 R-DDI-192067 https://reactome.org/PathwayBrowser/#/R-DDI-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Dictyostelium discoideum 15378 R-DDI-192160 https://reactome.org/PathwayBrowser/#/R-DDI-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Dictyostelium discoideum 15378 R-DDI-193064 https://reactome.org/PathwayBrowser/#/R-DDI-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Dictyostelium discoideum 15378 R-DDI-193455 https://reactome.org/PathwayBrowser/#/R-DDI-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 15378 R-DDI-193508 https://reactome.org/PathwayBrowser/#/R-DDI-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 15378 R-DDI-193746 https://reactome.org/PathwayBrowser/#/R-DDI-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Dictyostelium discoideum 15378 R-DDI-193755 https://reactome.org/PathwayBrowser/#/R-DDI-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Dictyostelium discoideum 15378 R-DDI-193758 https://reactome.org/PathwayBrowser/#/R-DDI-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Dictyostelium discoideum 15378 R-DDI-193781 https://reactome.org/PathwayBrowser/#/R-DDI-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Dictyostelium discoideum 15378 R-DDI-193800 https://reactome.org/PathwayBrowser/#/R-DDI-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Dictyostelium discoideum 15378 R-DDI-193821 https://reactome.org/PathwayBrowser/#/R-DDI-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Dictyostelium discoideum 15378 R-DDI-193824 https://reactome.org/PathwayBrowser/#/R-DDI-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Dictyostelium discoideum 15378 R-DDI-193841 https://reactome.org/PathwayBrowser/#/R-DDI-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Dictyostelium discoideum 15378 R-DDI-193964 https://reactome.org/PathwayBrowser/#/R-DDI-193964 CYP21A2 21-hydroxylates PROG IEA Dictyostelium discoideum 15378 R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 15378 R-DDI-194641 https://reactome.org/PathwayBrowser/#/R-DDI-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15378 R-DDI-194642 https://reactome.org/PathwayBrowser/#/R-DDI-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Dictyostelium discoideum 15378 R-DDI-194669 https://reactome.org/PathwayBrowser/#/R-DDI-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15378 R-DDI-194674 https://reactome.org/PathwayBrowser/#/R-DDI-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Dictyostelium discoideum 15378 R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 15378 R-DDI-194698 https://reactome.org/PathwayBrowser/#/R-DDI-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Dictyostelium discoideum 15378 R-DDI-194718 https://reactome.org/PathwayBrowser/#/R-DDI-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Dictyostelium discoideum 15378 R-DDI-196060 https://reactome.org/PathwayBrowser/#/R-DDI-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Dictyostelium discoideum 15378 R-DDI-196753 https://reactome.org/PathwayBrowser/#/R-DDI-196753 2xPPCS ligates PPanK with Cys IEA Dictyostelium discoideum 15378 R-DDI-196754 https://reactome.org/PathwayBrowser/#/R-DDI-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Dictyostelium discoideum 15378 R-DDI-196773 https://reactome.org/PathwayBrowser/#/R-DDI-196773 COASY phosphorylates DP-CoA IEA Dictyostelium discoideum 15378 R-DDI-196840 https://reactome.org/PathwayBrowser/#/R-DDI-196840 3xPPCDC:3FMN decarboxylates PPC IEA Dictyostelium discoideum 15378 R-DDI-196929 https://reactome.org/PathwayBrowser/#/R-DDI-196929 FLAD1 phosphorylates FMN IEA Dictyostelium discoideum 15378 R-DDI-196955 https://reactome.org/PathwayBrowser/#/R-DDI-196955 2xENPP1 hydrolyzes FAD to FMN IEA Dictyostelium discoideum 15378 R-DDI-197186 https://reactome.org/PathwayBrowser/#/R-DDI-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Dictyostelium discoideum 15378 R-DDI-197268 https://reactome.org/PathwayBrowser/#/R-DDI-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Dictyostelium discoideum 15378 R-DDI-197963 https://reactome.org/PathwayBrowser/#/R-DDI-197963 DHFR2 reduces FOLA to DHF IEA Dictyostelium discoideum 15378 R-DDI-197972 https://reactome.org/PathwayBrowser/#/R-DDI-197972 DHF is reduced to tetrahydrofolate (THF) IEA Dictyostelium discoideum 15378 R-DDI-198824 https://reactome.org/PathwayBrowser/#/R-DDI-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Dictyostelium discoideum 15378 R-DDI-200644 https://reactome.org/PathwayBrowser/#/R-DDI-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Dictyostelium discoideum 15378 R-DDI-200676 https://reactome.org/PathwayBrowser/#/R-DDI-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Dictyostelium discoideum 15378 R-DDI-200718 https://reactome.org/PathwayBrowser/#/R-DDI-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Dictyostelium discoideum 15378 R-DDI-204617 https://reactome.org/PathwayBrowser/#/R-DDI-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Dictyostelium discoideum 15378 R-DDI-204647 https://reactome.org/PathwayBrowser/#/R-DDI-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Dictyostelium discoideum 15378 R-DDI-204662 https://reactome.org/PathwayBrowser/#/R-DDI-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Dictyostelium discoideum 15378 R-DDI-209772 https://reactome.org/PathwayBrowser/#/R-DDI-209772 Thyroxine is deiodinated to triiodothyronine IEA Dictyostelium discoideum 15378 R-DDI-209821 https://reactome.org/PathwayBrowser/#/R-DDI-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Dictyostelium discoideum 15378 R-DDI-209845 https://reactome.org/PathwayBrowser/#/R-DDI-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Dictyostelium discoideum 15378 R-DDI-209973 https://reactome.org/PathwayBrowser/#/R-DDI-209973 Tyrosine is diiodinated IEA Dictyostelium discoideum 15378 R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 15378 R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 15378 R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 15378 R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 15378 R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 15378 R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 15378 R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 15378 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 15378 R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 15378 R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 15378 R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 15378 R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 15378 R-DDI-2161549 https://reactome.org/PathwayBrowser/#/R-DDI-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Dictyostelium discoideum 15378 R-DDI-2161614 https://reactome.org/PathwayBrowser/#/R-DDI-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Dictyostelium discoideum 15378 R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 15378 R-DDI-2161890 https://reactome.org/PathwayBrowser/#/R-DDI-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Dictyostelium discoideum 15378 R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Dictyostelium discoideum 15378 R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 15378 R-DDI-2162078 https://reactome.org/PathwayBrowser/#/R-DDI-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Dictyostelium discoideum 15378 R-DDI-2162186 https://reactome.org/PathwayBrowser/#/R-DDI-2162186 COQ3 methylates DeMQ10H2 IEA Dictyostelium discoideum 15378 R-DDI-2162188 https://reactome.org/PathwayBrowser/#/R-DDI-2162188 COQ5 methylates MDMQ10H2 IEA Dictyostelium discoideum 15378 R-DDI-2162193 https://reactome.org/PathwayBrowser/#/R-DDI-2162193 COQ3 methylates DHDB IEA Dictyostelium discoideum 15378 R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 15378 R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 15378 R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 15378 R-DDI-2395512 https://reactome.org/PathwayBrowser/#/R-DDI-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Dictyostelium discoideum 15378 R-DDI-2395517 https://reactome.org/PathwayBrowser/#/R-DDI-2395517 NADPH transfers electrons to FDXR IEA Dictyostelium discoideum 15378 R-DDI-2509827 https://reactome.org/PathwayBrowser/#/R-DDI-2509827 ITPA hydrolyses ITP to IMP IEA Dictyostelium discoideum 15378 R-DDI-2509831 https://reactome.org/PathwayBrowser/#/R-DDI-2509831 ITPA hydrolyses XTP to XMP IEA Dictyostelium discoideum 15378 R-DDI-2509838 https://reactome.org/PathwayBrowser/#/R-DDI-2509838 ITPA hydrolyses dITP to dIMP IEA Dictyostelium discoideum 15378 R-DDI-2730692 https://reactome.org/PathwayBrowser/#/R-DDI-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Dictyostelium discoideum 15378 R-DDI-3095889 https://reactome.org/PathwayBrowser/#/R-DDI-3095889 MMACHC dealkylates RCbl IEA Dictyostelium discoideum 15378 R-DDI-3149518 https://reactome.org/PathwayBrowser/#/R-DDI-3149518 MTRR reduces cob(II)alamin to meCbl IEA Dictyostelium discoideum 15378 R-DDI-3149519 https://reactome.org/PathwayBrowser/#/R-DDI-3149519 MMACHC decyanates CNCbl IEA Dictyostelium discoideum 15378 R-DDI-3159253 https://reactome.org/PathwayBrowser/#/R-DDI-3159253 MMAB adenosylates cob(I)alamin IEA Dictyostelium discoideum 15378 R-DDI-3299680 https://reactome.org/PathwayBrowser/#/R-DDI-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Dictyostelium discoideum 15378 R-DDI-3299682 https://reactome.org/PathwayBrowser/#/R-DDI-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Dictyostelium discoideum 15378 R-DDI-3299691 https://reactome.org/PathwayBrowser/#/R-DDI-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Dictyostelium discoideum 15378 R-DDI-3323079 https://reactome.org/PathwayBrowser/#/R-DDI-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 15378 R-DDI-350869 https://reactome.org/PathwayBrowser/#/R-DDI-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Dictyostelium discoideum 15378 R-DDI-350901 https://reactome.org/PathwayBrowser/#/R-DDI-350901 Iodide is organified IEA Dictyostelium discoideum 15378 R-DDI-372448 https://reactome.org/PathwayBrowser/#/R-DDI-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Dictyostelium discoideum 15378 R-DDI-375405 https://reactome.org/PathwayBrowser/#/R-DDI-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Dictyostelium discoideum 15378 R-DDI-375417 https://reactome.org/PathwayBrowser/#/R-DDI-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Dictyostelium discoideum 15378 R-DDI-3777112 https://reactome.org/PathwayBrowser/#/R-DDI-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Dictyostelium discoideum 15378 R-DDI-380608 https://reactome.org/PathwayBrowser/#/R-DDI-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Dictyostelium discoideum 15378 R-DDI-389540 https://reactome.org/PathwayBrowser/#/R-DDI-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 15378 R-DDI-389550 https://reactome.org/PathwayBrowser/#/R-DDI-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 15378 R-DDI-389609 https://reactome.org/PathwayBrowser/#/R-DDI-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Dictyostelium discoideum 15378 R-DDI-389995 https://reactome.org/PathwayBrowser/#/R-DDI-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Dictyostelium discoideum 15378 R-DDI-390251 https://reactome.org/PathwayBrowser/#/R-DDI-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Dictyostelium discoideum 15378 R-DDI-390425 https://reactome.org/PathwayBrowser/#/R-DDI-390425 FAR1 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 15378 R-DDI-390438 https://reactome.org/PathwayBrowser/#/R-DDI-390438 FAR2 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 15378 R-DDI-425965 https://reactome.org/PathwayBrowser/#/R-DDI-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Dictyostelium discoideum 15378 R-DDI-425983 https://reactome.org/PathwayBrowser/#/R-DDI-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Dictyostelium discoideum 15378 R-DDI-425994 https://reactome.org/PathwayBrowser/#/R-DDI-425994 Na+/H+ exchanger transport (at cell membrane) IEA Dictyostelium discoideum 15378 R-DDI-426015 https://reactome.org/PathwayBrowser/#/R-DDI-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Dictyostelium discoideum 15378 R-DDI-426043 https://reactome.org/PathwayBrowser/#/R-DDI-426043 2-AG hydrolysis to arachidonate by MAGL IEA Dictyostelium discoideum 15378 R-DDI-427555 https://reactome.org/PathwayBrowser/#/R-DDI-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Dictyostelium discoideum 15378 R-DDI-427998 https://reactome.org/PathwayBrowser/#/R-DDI-427998 Proton-coupled di- and tri-peptide cotransport IEA Dictyostelium discoideum 15378 R-DDI-428052 https://reactome.org/PathwayBrowser/#/R-DDI-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Dictyostelium discoideum 15378 R-DDI-428123 https://reactome.org/PathwayBrowser/#/R-DDI-428123 KDSR reduces 3-ketosphingoid IEA Dictyostelium discoideum 15378 R-DDI-428185 https://reactome.org/PathwayBrowser/#/R-DDI-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Dictyostelium discoideum 15378 R-DDI-428259 https://reactome.org/PathwayBrowser/#/R-DDI-428259 DEGS1 dehydrogenates dihydroceramide IEA Dictyostelium discoideum 15378 R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 15378 R-DDI-428273 https://reactome.org/PathwayBrowser/#/R-DDI-428273 SPHK1 phosphorylates sphingoid IEA Dictyostelium discoideum 15378 R-DDI-428585 https://reactome.org/PathwayBrowser/#/R-DDI-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Dictyostelium discoideum 15378 R-DDI-429101 https://reactome.org/PathwayBrowser/#/R-DDI-429101 HMIT co-transports myo-inositol with a proton IEA Dictyostelium discoideum 15378 R-DDI-429157 https://reactome.org/PathwayBrowser/#/R-DDI-429157 ABCC4 accumulation of dense granule contents IEA Dictyostelium discoideum 15378 R-DDI-434650 https://reactome.org/PathwayBrowser/#/R-DDI-434650 MATEs mediate extrusion of xenobiotics IEA Dictyostelium discoideum 15378 R-DDI-435171 https://reactome.org/PathwayBrowser/#/R-DDI-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Dictyostelium discoideum 15378 R-DDI-435349 https://reactome.org/PathwayBrowser/#/R-DDI-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Dictyostelium discoideum 15378 R-DDI-444393 https://reactome.org/PathwayBrowser/#/R-DDI-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-DDI-444419 https://reactome.org/PathwayBrowser/#/R-DDI-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-DDI-446277 https://reactome.org/PathwayBrowser/#/R-DDI-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-DDI-446278 https://reactome.org/PathwayBrowser/#/R-DDI-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-DDI-450971 https://reactome.org/PathwayBrowser/#/R-DDI-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Dictyostelium discoideum 15378 R-DDI-504054 https://reactome.org/PathwayBrowser/#/R-DDI-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Dictyostelium discoideum 15378 R-DDI-508369 https://reactome.org/PathwayBrowser/#/R-DDI-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Dictyostelium discoideum 15378 R-DDI-508473 https://reactome.org/PathwayBrowser/#/R-DDI-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Dictyostelium discoideum 15378 R-DDI-5340130 https://reactome.org/PathwayBrowser/#/R-DDI-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Dictyostelium discoideum 15378 R-DDI-5362522 https://reactome.org/PathwayBrowser/#/R-DDI-5362522 ALDHs oxidise atRAL to atRA IEA Dictyostelium discoideum 15378 R-DDI-5362564 https://reactome.org/PathwayBrowser/#/R-DDI-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Dictyostelium discoideum 15378 R-DDI-5419165 https://reactome.org/PathwayBrowser/#/R-DDI-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Dictyostelium discoideum 15378 R-DDI-5423647 https://reactome.org/PathwayBrowser/#/R-DDI-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Dictyostelium discoideum 15378 R-DDI-548818 https://reactome.org/PathwayBrowser/#/R-DDI-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Dictyostelium discoideum 15378 R-DDI-548831 https://reactome.org/PathwayBrowser/#/R-DDI-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Dictyostelium discoideum 15378 R-DDI-5615668 https://reactome.org/PathwayBrowser/#/R-DDI-5615668 AKR1C3 reduces atRAL to atROL IEA Dictyostelium discoideum 15378 R-DDI-5623643 https://reactome.org/PathwayBrowser/#/R-DDI-5623643 RDH13 reduces atRAL to atROL IEA Dictyostelium discoideum 15378 R-DDI-5652172 https://reactome.org/PathwayBrowser/#/R-DDI-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Dictyostelium discoideum 15378 R-DDI-5661256 https://reactome.org/PathwayBrowser/#/R-DDI-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Dictyostelium discoideum 15378 R-DDI-5662662 https://reactome.org/PathwayBrowser/#/R-DDI-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Dictyostelium discoideum 15378 R-DDI-5678327 https://reactome.org/PathwayBrowser/#/R-DDI-5678327 MIOX oxidises Ins to GlcA IEA Dictyostelium discoideum 15378 R-DDI-5690565 https://reactome.org/PathwayBrowser/#/R-DDI-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15378 R-DDI-5692237 https://reactome.org/PathwayBrowser/#/R-DDI-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Dictyostelium discoideum 15378 R-DDI-5692261 https://reactome.org/PathwayBrowser/#/R-DDI-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Dictyostelium discoideum 15378 R-DDI-5692283 https://reactome.org/PathwayBrowser/#/R-DDI-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Dictyostelium discoideum 15378 R-DDI-5693347 https://reactome.org/PathwayBrowser/#/R-DDI-5693347 CRYM reduces P2C to PPCA IEA Dictyostelium discoideum 15378 R-DDI-5693681 https://reactome.org/PathwayBrowser/#/R-DDI-5693681 DUOX1,2 reduce O2 to H2O2 IEA Dictyostelium discoideum 15378 R-DDI-5693691 https://reactome.org/PathwayBrowser/#/R-DDI-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Dictyostelium discoideum 15378 R-DDI-5693761 https://reactome.org/PathwayBrowser/#/R-DDI-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Dictyostelium discoideum 15378 R-DDI-5694018 https://reactome.org/PathwayBrowser/#/R-DDI-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Dictyostelium discoideum 15378 R-DDI-5696080 https://reactome.org/PathwayBrowser/#/R-DDI-5696080 ALDH3B1 oxidises HXAL to PALM IEA Dictyostelium discoideum 15378 R-DDI-5696091 https://reactome.org/PathwayBrowser/#/R-DDI-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Dictyostelium discoideum 15378 R-DDI-5696101 https://reactome.org/PathwayBrowser/#/R-DDI-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Dictyostelium discoideum 15378 R-DDI-5696822 https://reactome.org/PathwayBrowser/#/R-DDI-5696822 AKR1B15 reduces EST17b to E1 IEA Dictyostelium discoideum 15378 R-DDI-6783221 https://reactome.org/PathwayBrowser/#/R-DDI-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Dictyostelium discoideum 15378 R-DDI-6783939 https://reactome.org/PathwayBrowser/#/R-DDI-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 15378 R-DDI-6783955 https://reactome.org/PathwayBrowser/#/R-DDI-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 15378 R-DDI-6787642 https://reactome.org/PathwayBrowser/#/R-DDI-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Dictyostelium discoideum 15378 R-DDI-6789031 https://reactome.org/PathwayBrowser/#/R-DDI-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 15378 R-DDI-6789126 https://reactome.org/PathwayBrowser/#/R-DDI-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 15378 R-DDI-6793590 https://reactome.org/PathwayBrowser/#/R-DDI-6793590 LIPT2 transfers octanoyl group to GCSH IEA Dictyostelium discoideum 15378 R-DDI-6799722 https://reactome.org/PathwayBrowser/#/R-DDI-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Dictyostelium discoideum 15378 R-DDI-6806967 https://reactome.org/PathwayBrowser/#/R-DDI-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Dictyostelium discoideum 15378 R-DDI-6807557 https://reactome.org/PathwayBrowser/#/R-DDI-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Dictyostelium discoideum 15378 R-DDI-6808464 https://reactome.org/PathwayBrowser/#/R-DDI-6808464 ALDH3B2 oxidises HXAL to PALM IEA Dictyostelium discoideum 15378 R-DDI-6809287 https://reactome.org/PathwayBrowser/#/R-DDI-6809287 NUDT12 hydrolyses NADH to NMNH IEA Dictyostelium discoideum 15378 R-DDI-6813749 https://reactome.org/PathwayBrowser/#/R-DDI-6813749 ALDH1A1 oxidises GA to DGA IEA Dictyostelium discoideum 15378 R-DDI-6814153 https://reactome.org/PathwayBrowser/#/R-DDI-6814153 ADO oxidises 2AET to HTAU IEA Dictyostelium discoideum 15378 R-DDI-70333 https://reactome.org/PathwayBrowser/#/R-DDI-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Dictyostelium discoideum 15378 R-DDI-70377 https://reactome.org/PathwayBrowser/#/R-DDI-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Dictyostelium discoideum 15378 R-DDI-70449 https://reactome.org/PathwayBrowser/#/R-DDI-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Dictyostelium discoideum 15378 R-DDI-70482 https://reactome.org/PathwayBrowser/#/R-DDI-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Dictyostelium discoideum 15378 R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Dictyostelium discoideum 15378 R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Dictyostelium discoideum 15378 R-DDI-70664 https://reactome.org/PathwayBrowser/#/R-DDI-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 15378 R-DDI-70670 https://reactome.org/PathwayBrowser/#/R-DDI-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Dictyostelium discoideum 15378 R-DDI-70837 https://reactome.org/PathwayBrowser/#/R-DDI-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Dictyostelium discoideum 15378 R-DDI-70885 https://reactome.org/PathwayBrowser/#/R-DDI-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Dictyostelium discoideum 15378 R-DDI-70893 https://reactome.org/PathwayBrowser/#/R-DDI-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 15378 R-DDI-70906 https://reactome.org/PathwayBrowser/#/R-DDI-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Dictyostelium discoideum 15378 R-DDI-70938 https://reactome.org/PathwayBrowser/#/R-DDI-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Dictyostelium discoideum 15378 R-DDI-70940 https://reactome.org/PathwayBrowser/#/R-DDI-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Dictyostelium discoideum 15378 R-DDI-70941 https://reactome.org/PathwayBrowser/#/R-DDI-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Dictyostelium discoideum 15378 R-DDI-70975 https://reactome.org/PathwayBrowser/#/R-DDI-70975 CS acetylates OA to citrate IEA Dictyostelium discoideum 15378 R-DDI-71130 https://reactome.org/PathwayBrowser/#/R-DDI-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Dictyostelium discoideum 15378 R-DDI-71164 https://reactome.org/PathwayBrowser/#/R-DDI-71164 HGD dioxygenates homogentisate IEA Dictyostelium discoideum 15378 R-DDI-71181 https://reactome.org/PathwayBrowser/#/R-DDI-71181 FAH cleaves 4FAA IEA Dictyostelium discoideum 15378 R-DDI-71200 https://reactome.org/PathwayBrowser/#/R-DDI-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Dictyostelium discoideum 15378 R-DDI-71299 https://reactome.org/PathwayBrowser/#/R-DDI-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 15378 R-DDI-71401 https://reactome.org/PathwayBrowser/#/R-DDI-71401 OGDH dimer decarboxylates 2-OG IEA Dictyostelium discoideum 15378 R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 15378 R-DDI-71682 https://reactome.org/PathwayBrowser/#/R-DDI-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 15378 R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 15378 R-DDI-71707 https://reactome.org/PathwayBrowser/#/R-DDI-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Dictyostelium discoideum 15378 R-DDI-71723 https://reactome.org/PathwayBrowser/#/R-DDI-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Dictyostelium discoideum 15378 R-DDI-73564 https://reactome.org/PathwayBrowser/#/R-DDI-73564 UMPS dimer decarboxylates OMP to UMP IEA Dictyostelium discoideum 15378 R-DDI-73571 https://reactome.org/PathwayBrowser/#/R-DDI-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Dictyostelium discoideum 15378 R-DDI-73573 https://reactome.org/PathwayBrowser/#/R-DDI-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Dictyostelium discoideum 15378 R-DDI-73577 https://reactome.org/PathwayBrowser/#/R-DDI-73577 CAD hexamer transforms L-Gln to CAP IEA Dictyostelium discoideum 15378 R-DDI-73585 https://reactome.org/PathwayBrowser/#/R-DDI-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Dictyostelium discoideum 15378 R-DDI-73589 https://reactome.org/PathwayBrowser/#/R-DDI-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Dictyostelium discoideum 15378 R-DDI-73591 https://reactome.org/PathwayBrowser/#/R-DDI-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Dictyostelium discoideum 15378 R-DDI-73616 https://reactome.org/PathwayBrowser/#/R-DDI-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Dictyostelium discoideum 15378 R-DDI-73618 https://reactome.org/PathwayBrowser/#/R-DDI-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Dictyostelium discoideum 15378 R-DDI-73620 https://reactome.org/PathwayBrowser/#/R-DDI-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Dictyostelium discoideum 15378 R-DDI-73647 https://reactome.org/PathwayBrowser/#/R-DDI-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Dictyostelium discoideum 15378 R-DDI-73666 https://reactome.org/PathwayBrowser/#/R-DDI-73666 dUTP + H2O => dUMP + pyrophosphate IEA Dictyostelium discoideum 15378 R-DDI-73792 https://reactome.org/PathwayBrowser/#/R-DDI-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Dictyostelium discoideum 15378 R-DDI-73794 https://reactome.org/PathwayBrowser/#/R-DDI-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Dictyostelium discoideum 15378 R-DDI-73810 https://reactome.org/PathwayBrowser/#/R-DDI-73810 FGAM + ATP => AIR + ADP + Pi IEA Dictyostelium discoideum 15378 R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 15378 R-DDI-73813 https://reactome.org/PathwayBrowser/#/R-DDI-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Dictyostelium discoideum 15378 R-DDI-73814 https://reactome.org/PathwayBrowser/#/R-DDI-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Dictyostelium discoideum 15378 R-DDI-74255 https://reactome.org/PathwayBrowser/#/R-DDI-74255 Guanine + H2O => Xanthine + NH4+ IEA Dictyostelium discoideum 15378 R-DDI-74723 https://reactome.org/PathwayBrowser/#/R-DDI-74723 Endosome acidification IEA Dictyostelium discoideum 15378 R-DDI-75872 https://reactome.org/PathwayBrowser/#/R-DDI-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Dictyostelium discoideum 15378 R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 15378 R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 15378 R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 15378 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 15378 R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 15378 R-DDI-804969 https://reactome.org/PathwayBrowser/#/R-DDI-804969 HSD17B1 hydrogenates E1 to EST17b IEA Dictyostelium discoideum 15378 R-DDI-8847579 https://reactome.org/PathwayBrowser/#/R-DDI-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15378 R-DDI-8862152 https://reactome.org/PathwayBrowser/#/R-DDI-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Dictyostelium discoideum 15378 R-DDI-8866601 https://reactome.org/PathwayBrowser/#/R-DDI-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Dictyostelium discoideum 15378 R-DDI-8869606 https://reactome.org/PathwayBrowser/#/R-DDI-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 15378 R-DDI-8869607 https://reactome.org/PathwayBrowser/#/R-DDI-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 15378 R-DDI-8869627 https://reactome.org/PathwayBrowser/#/R-DDI-8869627 NMRK2 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 15378 R-DDI-8869633 https://reactome.org/PathwayBrowser/#/R-DDI-8869633 NMRK1 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 15378 R-DDI-8875623 https://reactome.org/PathwayBrowser/#/R-DDI-8875623 SLC25A18,22 import L-Glu, H+ IEA Dictyostelium discoideum 15378 R-DDI-8933635 https://reactome.org/PathwayBrowser/#/R-DDI-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Dictyostelium discoideum 15378 R-DDI-8936442 https://reactome.org/PathwayBrowser/#/R-DDI-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Dictyostelium discoideum 15378 R-DDI-8952873 https://reactome.org/PathwayBrowser/#/R-DDI-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Dictyostelium discoideum 15378 R-DDI-8954468 https://reactome.org/PathwayBrowser/#/R-DDI-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Dictyostelium discoideum 15378 R-DDI-8955760 https://reactome.org/PathwayBrowser/#/R-DDI-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Dictyostelium discoideum 15378 R-DDI-8959510 https://reactome.org/PathwayBrowser/#/R-DDI-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Dictyostelium discoideum 15378 R-DDI-9011595 https://reactome.org/PathwayBrowser/#/R-DDI-9011595 GSTZ1 dimer dehalogenates DCA IEA Dictyostelium discoideum 15378 R-DDI-9012016 https://reactome.org/PathwayBrowser/#/R-DDI-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Dictyostelium discoideum 15378 R-DDI-9024993 https://reactome.org/PathwayBrowser/#/R-DDI-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Dictyostelium discoideum 15378 R-DDI-9027043 https://reactome.org/PathwayBrowser/#/R-DDI-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Dictyostelium discoideum 15378 R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 15378 R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 15378 R-DDI-917841 https://reactome.org/PathwayBrowser/#/R-DDI-917841 Acidification of Tf:TfR1 containing endosome IEA Dictyostelium discoideum 15378 R-DDI-917979 https://reactome.org/PathwayBrowser/#/R-DDI-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Dictyostelium discoideum 15378 R-DDI-9620103 https://reactome.org/PathwayBrowser/#/R-DDI-9620103 ALDH2 transforms GTN to NO IEA Dictyostelium discoideum 15378 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 15378 R-DDI-9705714 https://reactome.org/PathwayBrowser/#/R-DDI-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Dictyostelium discoideum 15378 R-DDI-9709098 https://reactome.org/PathwayBrowser/#/R-DDI-9709098 DHFR dimer reduces FOLA to DHF IEA Dictyostelium discoideum 15378 R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 15378 R-DDI-9727349 https://reactome.org/PathwayBrowser/#/R-DDI-9727349 XDH dehydrogenates xanthine to form urate IEA Dictyostelium discoideum 15378 R-DDI-9748945 https://reactome.org/PathwayBrowser/#/R-DDI-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Dictyostelium discoideum 15378 R-DDI-9748957 https://reactome.org/PathwayBrowser/#/R-DDI-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Dictyostelium discoideum 15378 R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 15378 R-DDI-9749647 https://reactome.org/PathwayBrowser/#/R-DDI-9749647 CES2 hydrolyzes ASA- IEA Dictyostelium discoideum 15378 R-DDI-9749792 https://reactome.org/PathwayBrowser/#/R-DDI-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Dictyostelium discoideum 15378 R-DDI-9753285 https://reactome.org/PathwayBrowser/#/R-DDI-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Dictyostelium discoideum 15378 R-DDI-9756134 https://reactome.org/PathwayBrowser/#/R-DDI-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Dictyostelium discoideum 15378 R-DDI-9756156 https://reactome.org/PathwayBrowser/#/R-DDI-9756156 UGT1A3 lactonizes ATV to ATVL IEA Dictyostelium discoideum 15378 R-DDI-9756183 https://reactome.org/PathwayBrowser/#/R-DDI-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Dictyostelium discoideum 15378 R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 15378 R-DDI-9758682 https://reactome.org/PathwayBrowser/#/R-DDI-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Dictyostelium discoideum 15378 R-DDI-9759549 https://reactome.org/PathwayBrowser/#/R-DDI-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Dictyostelium discoideum 15378 R-DDI-9843721 https://reactome.org/PathwayBrowser/#/R-DDI-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Dictyostelium discoideum 15378 R-DDI-9853499 https://reactome.org/PathwayBrowser/#/R-DDI-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 15378 R-DDI-9856871 https://reactome.org/PathwayBrowser/#/R-DDI-9856871 MDH1 reduces OA IEA Dictyostelium discoideum 15378 R-DDI-9861616 https://reactome.org/PathwayBrowser/#/R-DDI-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 15378 R-DDI-9861734 https://reactome.org/PathwayBrowser/#/R-DDI-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Dictyostelium discoideum 15378 R-DME-111524 https://reactome.org/PathwayBrowser/#/R-DME-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Drosophila melanogaster 15378 R-DME-1222516 https://reactome.org/PathwayBrowser/#/R-DME-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Drosophila melanogaster 15378 R-DME-1237045 https://reactome.org/PathwayBrowser/#/R-DME-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Drosophila melanogaster 15378 R-DME-1237047 https://reactome.org/PathwayBrowser/#/R-DME-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Drosophila melanogaster 15378 R-DME-1237059 https://reactome.org/PathwayBrowser/#/R-DME-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Drosophila melanogaster 15378 R-DME-1237081 https://reactome.org/PathwayBrowser/#/R-DME-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Drosophila melanogaster 15378 R-DME-1237129 https://reactome.org/PathwayBrowser/#/R-DME-1237129 Acireductone is created IEA Drosophila melanogaster 15378 R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 15378 R-DME-1475017 https://reactome.org/PathwayBrowser/#/R-DME-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Drosophila melanogaster 15378 R-DME-1475022 https://reactome.org/PathwayBrowser/#/R-DME-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Drosophila melanogaster 15378 R-DME-1475025 https://reactome.org/PathwayBrowser/#/R-DME-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Drosophila melanogaster 15378 R-DME-1475026 https://reactome.org/PathwayBrowser/#/R-DME-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Drosophila melanogaster 15378 R-DME-1475028 https://reactome.org/PathwayBrowser/#/R-DME-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Drosophila melanogaster 15378 R-DME-1475032 https://reactome.org/PathwayBrowser/#/R-DME-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Drosophila melanogaster 15378 R-DME-1475435 https://reactome.org/PathwayBrowser/#/R-DME-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Drosophila melanogaster 15378 R-DME-1475436 https://reactome.org/PathwayBrowser/#/R-DME-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Drosophila melanogaster 15378 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 15378 R-DME-1497869 https://reactome.org/PathwayBrowser/#/R-DME-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Drosophila melanogaster 15378 R-DME-1562626 https://reactome.org/PathwayBrowser/#/R-DME-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Drosophila melanogaster 15378 R-DME-156526 https://reactome.org/PathwayBrowser/#/R-DME-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Drosophila melanogaster 15378 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 15378 R-DME-1605797 https://reactome.org/PathwayBrowser/#/R-DME-1605797 SMPD1 hydrolyzes SPHM IEA Drosophila melanogaster 15378 R-DME-1606273 https://reactome.org/PathwayBrowser/#/R-DME-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Drosophila melanogaster 15378 R-DME-1606288 https://reactome.org/PathwayBrowser/#/R-DME-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Drosophila melanogaster 15378 R-DME-1614605 https://reactome.org/PathwayBrowser/#/R-DME-1614605 Persulfide sulfur is dioxygenated IEA Drosophila melanogaster 15378 R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 15378 R-DME-163217 https://reactome.org/PathwayBrowser/#/R-DME-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Drosophila melanogaster 15378 R-DME-1638104 https://reactome.org/PathwayBrowser/#/R-DME-1638104 UGCG transfers glucose to ceramide IEA Drosophila melanogaster 15378 R-DME-1638845 https://reactome.org/PathwayBrowser/#/R-DME-1638845 CERK phosphorylates CERA to form C1P IEA Drosophila melanogaster 15378 R-DME-164651 https://reactome.org/PathwayBrowser/#/R-DME-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Drosophila melanogaster 15378 R-DME-164834 https://reactome.org/PathwayBrowser/#/R-DME-164834 Enzyme-bound ATP is released IEA Drosophila melanogaster 15378 R-DME-170026 https://reactome.org/PathwayBrowser/#/R-DME-170026 Protons are translocated from the intermembrane space to the matrix IEA Drosophila melanogaster 15378 R-DME-173597 https://reactome.org/PathwayBrowser/#/R-DME-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Drosophila melanogaster 15378 R-DME-174389 https://reactome.org/PathwayBrowser/#/R-DME-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Drosophila melanogaster 15378 R-DME-174392 https://reactome.org/PathwayBrowser/#/R-DME-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Drosophila melanogaster 15378 R-DME-189421 https://reactome.org/PathwayBrowser/#/R-DME-189421 CPO transforms COPRO3 to PPGEN9 IEA Drosophila melanogaster 15378 R-DME-189425 https://reactome.org/PathwayBrowser/#/R-DME-189425 UROD decarboxylates URO3 to COPRO3 IEA Drosophila melanogaster 15378 R-DME-189439 https://reactome.org/PathwayBrowser/#/R-DME-189439 ALAD condenses 2 dALAs to form PBG IEA Drosophila melanogaster 15378 R-DME-189442 https://reactome.org/PathwayBrowser/#/R-DME-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Drosophila melanogaster 15378 R-DME-189465 https://reactome.org/PathwayBrowser/#/R-DME-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Drosophila melanogaster 15378 R-DME-190182 https://reactome.org/PathwayBrowser/#/R-DME-190182 UROD decarboxylates URO1 to COPRO1 IEA Drosophila melanogaster 15378 R-DME-191323 https://reactome.org/PathwayBrowser/#/R-DME-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Drosophila melanogaster 15378 R-DME-191352 https://reactome.org/PathwayBrowser/#/R-DME-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Drosophila melanogaster 15378 R-DME-192033 https://reactome.org/PathwayBrowser/#/R-DME-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Drosophila melanogaster 15378 R-DME-192036 https://reactome.org/PathwayBrowser/#/R-DME-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Drosophila melanogaster 15378 R-DME-192067 https://reactome.org/PathwayBrowser/#/R-DME-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Drosophila melanogaster 15378 R-DME-192160 https://reactome.org/PathwayBrowser/#/R-DME-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Drosophila melanogaster 15378 R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 15378 R-DME-193064 https://reactome.org/PathwayBrowser/#/R-DME-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Drosophila melanogaster 15378 R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 15378 R-DME-193455 https://reactome.org/PathwayBrowser/#/R-DME-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 15378 R-DME-193508 https://reactome.org/PathwayBrowser/#/R-DME-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 15378 R-DME-193746 https://reactome.org/PathwayBrowser/#/R-DME-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Drosophila melanogaster 15378 R-DME-193755 https://reactome.org/PathwayBrowser/#/R-DME-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Drosophila melanogaster 15378 R-DME-193758 https://reactome.org/PathwayBrowser/#/R-DME-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Drosophila melanogaster 15378 R-DME-193781 https://reactome.org/PathwayBrowser/#/R-DME-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Drosophila melanogaster 15378 R-DME-193800 https://reactome.org/PathwayBrowser/#/R-DME-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Drosophila melanogaster 15378 R-DME-193821 https://reactome.org/PathwayBrowser/#/R-DME-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Drosophila melanogaster 15378 R-DME-193824 https://reactome.org/PathwayBrowser/#/R-DME-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Drosophila melanogaster 15378 R-DME-193841 https://reactome.org/PathwayBrowser/#/R-DME-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Drosophila melanogaster 15378 R-DME-194023 https://reactome.org/PathwayBrowser/#/R-DME-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Drosophila melanogaster 15378 R-DME-194698 https://reactome.org/PathwayBrowser/#/R-DME-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Drosophila melanogaster 15378 R-DME-196060 https://reactome.org/PathwayBrowser/#/R-DME-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Drosophila melanogaster 15378 R-DME-196753 https://reactome.org/PathwayBrowser/#/R-DME-196753 2xPPCS ligates PPanK with Cys IEA Drosophila melanogaster 15378 R-DME-196840 https://reactome.org/PathwayBrowser/#/R-DME-196840 3xPPCDC:3FMN decarboxylates PPC IEA Drosophila melanogaster 15378 R-DME-196857 https://reactome.org/PathwayBrowser/#/R-DME-196857 PANK2 phosphorylates PanK IEA Drosophila melanogaster 15378 R-DME-196929 https://reactome.org/PathwayBrowser/#/R-DME-196929 FLAD1 phosphorylates FMN IEA Drosophila melanogaster 15378 R-DME-196964 https://reactome.org/PathwayBrowser/#/R-DME-196964 RFK:Mg2+ phosphorylates RIB IEA Drosophila melanogaster 15378 R-DME-197186 https://reactome.org/PathwayBrowser/#/R-DME-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Drosophila melanogaster 15378 R-DME-197963 https://reactome.org/PathwayBrowser/#/R-DME-197963 DHFR2 reduces FOLA to DHF IEA Drosophila melanogaster 15378 R-DME-197972 https://reactome.org/PathwayBrowser/#/R-DME-197972 DHF is reduced to tetrahydrofolate (THF) IEA Drosophila melanogaster 15378 R-DME-198824 https://reactome.org/PathwayBrowser/#/R-DME-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Drosophila melanogaster 15378 R-DME-199203 https://reactome.org/PathwayBrowser/#/R-DME-199203 PANK1/3 phosphorylate PanK IEA Drosophila melanogaster 15378 R-DME-200644 https://reactome.org/PathwayBrowser/#/R-DME-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Drosophila melanogaster 15378 R-DME-200676 https://reactome.org/PathwayBrowser/#/R-DME-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Drosophila melanogaster 15378 R-DME-200718 https://reactome.org/PathwayBrowser/#/R-DME-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Drosophila melanogaster 15378 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 15378 R-DME-204617 https://reactome.org/PathwayBrowser/#/R-DME-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Drosophila melanogaster 15378 R-DME-204647 https://reactome.org/PathwayBrowser/#/R-DME-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Drosophila melanogaster 15378 R-DME-204662 https://reactome.org/PathwayBrowser/#/R-DME-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Drosophila melanogaster 15378 R-DME-209845 https://reactome.org/PathwayBrowser/#/R-DME-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Drosophila melanogaster 15378 R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 15378 R-DME-210404 https://reactome.org/PathwayBrowser/#/R-DME-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Drosophila melanogaster 15378 R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 15378 R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 15378 R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 15378 R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 15378 R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 15378 R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 15378 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 15378 R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 15378 R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 15378 R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 15378 R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 15378 R-DME-2161187 https://reactome.org/PathwayBrowser/#/R-DME-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Drosophila melanogaster 15378 R-DME-2161549 https://reactome.org/PathwayBrowser/#/R-DME-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Drosophila melanogaster 15378 R-DME-2161614 https://reactome.org/PathwayBrowser/#/R-DME-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Drosophila melanogaster 15378 R-DME-2161779 https://reactome.org/PathwayBrowser/#/R-DME-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Drosophila melanogaster 15378 R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 15378 R-DME-2161890 https://reactome.org/PathwayBrowser/#/R-DME-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Drosophila melanogaster 15378 R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Drosophila melanogaster 15378 R-DME-2162078 https://reactome.org/PathwayBrowser/#/R-DME-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Drosophila melanogaster 15378 R-DME-2162186 https://reactome.org/PathwayBrowser/#/R-DME-2162186 COQ3 methylates DeMQ10H2 IEA Drosophila melanogaster 15378 R-DME-2162188 https://reactome.org/PathwayBrowser/#/R-DME-2162188 COQ5 methylates MDMQ10H2 IEA Drosophila melanogaster 15378 R-DME-2162193 https://reactome.org/PathwayBrowser/#/R-DME-2162193 COQ3 methylates DHDB IEA Drosophila melanogaster 15378 R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 15378 R-DME-2395512 https://reactome.org/PathwayBrowser/#/R-DME-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Drosophila melanogaster 15378 R-DME-2395517 https://reactome.org/PathwayBrowser/#/R-DME-2395517 NADPH transfers electrons to FDXR IEA Drosophila melanogaster 15378 R-DME-2395873 https://reactome.org/PathwayBrowser/#/R-DME-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Drosophila melanogaster 15378 R-DME-2395879 https://reactome.org/PathwayBrowser/#/R-DME-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Drosophila melanogaster 15378 R-DME-2395965 https://reactome.org/PathwayBrowser/#/R-DME-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Drosophila melanogaster 15378 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 15378 R-DME-2464822 https://reactome.org/PathwayBrowser/#/R-DME-2464822 RDH12 reduces atRAL to atROL IEA Drosophila melanogaster 15378 R-DME-2465940 https://reactome.org/PathwayBrowser/#/R-DME-2465940 atRAL is reduced to atROL IEA Drosophila melanogaster 15378 R-DME-2509827 https://reactome.org/PathwayBrowser/#/R-DME-2509827 ITPA hydrolyses ITP to IMP IEA Drosophila melanogaster 15378 R-DME-2509831 https://reactome.org/PathwayBrowser/#/R-DME-2509831 ITPA hydrolyses XTP to XMP IEA Drosophila melanogaster 15378 R-DME-2509838 https://reactome.org/PathwayBrowser/#/R-DME-2509838 ITPA hydrolyses dITP to dIMP IEA Drosophila melanogaster 15378 R-DME-264615 https://reactome.org/PathwayBrowser/#/R-DME-264615 Loading of acetylcholine in synaptic vesicles IEA Drosophila melanogaster 15378 R-DME-2671885 https://reactome.org/PathwayBrowser/#/R-DME-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Drosophila melanogaster 15378 R-DME-2730692 https://reactome.org/PathwayBrowser/#/R-DME-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Drosophila melanogaster 15378 R-DME-2730959 https://reactome.org/PathwayBrowser/#/R-DME-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Drosophila melanogaster 15378 R-DME-2855252 https://reactome.org/PathwayBrowser/#/R-DME-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 15378 R-DME-2872444 https://reactome.org/PathwayBrowser/#/R-DME-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Drosophila melanogaster 15378 R-DME-2889070 https://reactome.org/PathwayBrowser/#/R-DME-2889070 SLC9B2 exchanges Na+ for H+ IEA Drosophila melanogaster 15378 R-DME-3299680 https://reactome.org/PathwayBrowser/#/R-DME-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Drosophila melanogaster 15378 R-DME-3299691 https://reactome.org/PathwayBrowser/#/R-DME-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Drosophila melanogaster 15378 R-DME-3323050 https://reactome.org/PathwayBrowser/#/R-DME-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Drosophila melanogaster 15378 R-DME-350901 https://reactome.org/PathwayBrowser/#/R-DME-350901 Iodide is organified IEA Drosophila melanogaster 15378 R-DME-352174 https://reactome.org/PathwayBrowser/#/R-DME-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Drosophila melanogaster 15378 R-DME-352182 https://reactome.org/PathwayBrowser/#/R-DME-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Drosophila melanogaster 15378 R-DME-372448 https://reactome.org/PathwayBrowser/#/R-DME-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Drosophila melanogaster 15378 R-DME-373867 https://reactome.org/PathwayBrowser/#/R-DME-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-DME-373875 https://reactome.org/PathwayBrowser/#/R-DME-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Drosophila melanogaster 15378 R-DME-375405 https://reactome.org/PathwayBrowser/#/R-DME-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-DME-375417 https://reactome.org/PathwayBrowser/#/R-DME-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Drosophila melanogaster 15378 R-DME-3777112 https://reactome.org/PathwayBrowser/#/R-DME-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Drosophila melanogaster 15378 R-DME-380608 https://reactome.org/PathwayBrowser/#/R-DME-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Drosophila melanogaster 15378 R-DME-389540 https://reactome.org/PathwayBrowser/#/R-DME-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 15378 R-DME-389550 https://reactome.org/PathwayBrowser/#/R-DME-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 15378 R-DME-389609 https://reactome.org/PathwayBrowser/#/R-DME-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Drosophila melanogaster 15378 R-DME-389826 https://reactome.org/PathwayBrowser/#/R-DME-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Drosophila melanogaster 15378 R-DME-389995 https://reactome.org/PathwayBrowser/#/R-DME-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Drosophila melanogaster 15378 R-DME-390251 https://reactome.org/PathwayBrowser/#/R-DME-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Drosophila melanogaster 15378 R-DME-390425 https://reactome.org/PathwayBrowser/#/R-DME-390425 FAR1 reduces PalmCoA to HXOL IEA Drosophila melanogaster 15378 R-DME-390438 https://reactome.org/PathwayBrowser/#/R-DME-390438 FAR2 reduces PalmCoA to HXOL IEA Drosophila melanogaster 15378 R-DME-418365 https://reactome.org/PathwayBrowser/#/R-DME-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Drosophila melanogaster 15378 R-DME-425577 https://reactome.org/PathwayBrowser/#/R-DME-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Drosophila melanogaster 15378 R-DME-425965 https://reactome.org/PathwayBrowser/#/R-DME-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Drosophila melanogaster 15378 R-DME-425983 https://reactome.org/PathwayBrowser/#/R-DME-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Drosophila melanogaster 15378 R-DME-425994 https://reactome.org/PathwayBrowser/#/R-DME-425994 Na+/H+ exchanger transport (at cell membrane) IEA Drosophila melanogaster 15378 R-DME-426015 https://reactome.org/PathwayBrowser/#/R-DME-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Drosophila melanogaster 15378 R-DME-427555 https://reactome.org/PathwayBrowser/#/R-DME-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-DME-427910 https://reactome.org/PathwayBrowser/#/R-DME-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Drosophila melanogaster 15378 R-DME-427998 https://reactome.org/PathwayBrowser/#/R-DME-427998 Proton-coupled di- and tri-peptide cotransport IEA Drosophila melanogaster 15378 R-DME-428015 https://reactome.org/PathwayBrowser/#/R-DME-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-DME-428052 https://reactome.org/PathwayBrowser/#/R-DME-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Drosophila melanogaster 15378 R-DME-428123 https://reactome.org/PathwayBrowser/#/R-DME-428123 KDSR reduces 3-ketosphingoid IEA Drosophila melanogaster 15378 R-DME-428127 https://reactome.org/PathwayBrowser/#/R-DME-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Drosophila melanogaster 15378 R-DME-428185 https://reactome.org/PathwayBrowser/#/R-DME-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Drosophila melanogaster 15378 R-DME-428259 https://reactome.org/PathwayBrowser/#/R-DME-428259 DEGS1 dehydrogenates dihydroceramide IEA Drosophila melanogaster 15378 R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 15378 R-DME-428273 https://reactome.org/PathwayBrowser/#/R-DME-428273 SPHK1 phosphorylates sphingoid IEA Drosophila melanogaster 15378 R-DME-428585 https://reactome.org/PathwayBrowser/#/R-DME-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Drosophila melanogaster 15378 R-DME-428625 https://reactome.org/PathwayBrowser/#/R-DME-428625 Vesicular inhibitory amino acid transport IEA Drosophila melanogaster 15378 R-DME-429157 https://reactome.org/PathwayBrowser/#/R-DME-429157 ABCC4 accumulation of dense granule contents IEA Drosophila melanogaster 15378 R-DME-429698 https://reactome.org/PathwayBrowser/#/R-DME-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Drosophila melanogaster 15378 R-DME-429714 https://reactome.org/PathwayBrowser/#/R-DME-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Drosophila melanogaster 15378 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-DME-435171 https://reactome.org/PathwayBrowser/#/R-DME-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Drosophila melanogaster 15378 R-DME-435349 https://reactome.org/PathwayBrowser/#/R-DME-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-DME-444393 https://reactome.org/PathwayBrowser/#/R-DME-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Drosophila melanogaster 15378 R-DME-444419 https://reactome.org/PathwayBrowser/#/R-DME-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Drosophila melanogaster 15378 R-DME-446277 https://reactome.org/PathwayBrowser/#/R-DME-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Drosophila melanogaster 15378 R-DME-446278 https://reactome.org/PathwayBrowser/#/R-DME-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Drosophila melanogaster 15378 R-DME-504054 https://reactome.org/PathwayBrowser/#/R-DME-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Drosophila melanogaster 15378 R-DME-508040 https://reactome.org/PathwayBrowser/#/R-DME-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Drosophila melanogaster 15378 R-DME-508369 https://reactome.org/PathwayBrowser/#/R-DME-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Drosophila melanogaster 15378 R-DME-508473 https://reactome.org/PathwayBrowser/#/R-DME-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Drosophila melanogaster 15378 R-DME-5340130 https://reactome.org/PathwayBrowser/#/R-DME-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Drosophila melanogaster 15378 R-DME-5362518 https://reactome.org/PathwayBrowser/#/R-DME-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Drosophila melanogaster 15378 R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster 15378 R-DME-5362564 https://reactome.org/PathwayBrowser/#/R-DME-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Drosophila melanogaster 15378 R-DME-5362721 https://reactome.org/PathwayBrowser/#/R-DME-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 15378 R-DME-5419165 https://reactome.org/PathwayBrowser/#/R-DME-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Drosophila melanogaster 15378 R-DME-5423647 https://reactome.org/PathwayBrowser/#/R-DME-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Drosophila melanogaster 15378 R-DME-548818 https://reactome.org/PathwayBrowser/#/R-DME-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Drosophila melanogaster 15378 R-DME-548831 https://reactome.org/PathwayBrowser/#/R-DME-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Drosophila melanogaster 15378 R-DME-5615668 https://reactome.org/PathwayBrowser/#/R-DME-5615668 AKR1C3 reduces atRAL to atROL IEA Drosophila melanogaster 15378 R-DME-5652172 https://reactome.org/PathwayBrowser/#/R-DME-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Drosophila melanogaster 15378 R-DME-5652195 https://reactome.org/PathwayBrowser/#/R-DME-5652195 SORD oxidizes D-sorbitol to Fru IEA Drosophila melanogaster 15378 R-DME-5661240 https://reactome.org/PathwayBrowser/#/R-DME-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Drosophila melanogaster 15378 R-DME-5661256 https://reactome.org/PathwayBrowser/#/R-DME-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Drosophila melanogaster 15378 R-DME-5661290 https://reactome.org/PathwayBrowser/#/R-DME-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Drosophila melanogaster 15378 R-DME-5662471 https://reactome.org/PathwayBrowser/#/R-DME-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Drosophila melanogaster 15378 R-DME-5678327 https://reactome.org/PathwayBrowser/#/R-DME-5678327 MIOX oxidises Ins to GlcA IEA Drosophila melanogaster 15378 R-DME-5690565 https://reactome.org/PathwayBrowser/#/R-DME-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15378 R-DME-5691107 https://reactome.org/PathwayBrowser/#/R-DME-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Drosophila melanogaster 15378 R-DME-5692237 https://reactome.org/PathwayBrowser/#/R-DME-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Drosophila melanogaster 15378 R-DME-5692261 https://reactome.org/PathwayBrowser/#/R-DME-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Drosophila melanogaster 15378 R-DME-5692283 https://reactome.org/PathwayBrowser/#/R-DME-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Drosophila melanogaster 15378 R-DME-5693347 https://reactome.org/PathwayBrowser/#/R-DME-5693347 CRYM reduces P2C to PPCA IEA Drosophila melanogaster 15378 R-DME-5693390 https://reactome.org/PathwayBrowser/#/R-DME-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Drosophila melanogaster 15378 R-DME-5693681 https://reactome.org/PathwayBrowser/#/R-DME-5693681 DUOX1,2 reduce O2 to H2O2 IEA Drosophila melanogaster 15378 R-DME-5693691 https://reactome.org/PathwayBrowser/#/R-DME-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Drosophila melanogaster 15378 R-DME-5693761 https://reactome.org/PathwayBrowser/#/R-DME-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Drosophila melanogaster 15378 R-DME-5694018 https://reactome.org/PathwayBrowser/#/R-DME-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Drosophila melanogaster 15378 R-DME-5694462 https://reactome.org/PathwayBrowser/#/R-DME-5694462 ABHD6,12 hydrolyse 3AG IEA Drosophila melanogaster 15378 R-DME-5696080 https://reactome.org/PathwayBrowser/#/R-DME-5696080 ALDH3B1 oxidises HXAL to PALM IEA Drosophila melanogaster 15378 R-DME-5696091 https://reactome.org/PathwayBrowser/#/R-DME-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Drosophila melanogaster 15378 R-DME-5696822 https://reactome.org/PathwayBrowser/#/R-DME-5696822 AKR1B15 reduces EST17b to E1 IEA Drosophila melanogaster 15378 R-DME-6783221 https://reactome.org/PathwayBrowser/#/R-DME-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Drosophila melanogaster 15378 R-DME-6783939 https://reactome.org/PathwayBrowser/#/R-DME-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 15378 R-DME-6786239 https://reactome.org/PathwayBrowser/#/R-DME-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Drosophila melanogaster 15378 R-DME-6787642 https://reactome.org/PathwayBrowser/#/R-DME-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Drosophila melanogaster 15378 R-DME-6789031 https://reactome.org/PathwayBrowser/#/R-DME-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 15378 R-DME-6789126 https://reactome.org/PathwayBrowser/#/R-DME-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 15378 R-DME-6793590 https://reactome.org/PathwayBrowser/#/R-DME-6793590 LIPT2 transfers octanoyl group to GCSH IEA Drosophila melanogaster 15378 R-DME-6793591 https://reactome.org/PathwayBrowser/#/R-DME-6793591 LIAS synthesizes lipoyl-GCSH IEA Drosophila melanogaster 15378 R-DME-6799495 https://reactome.org/PathwayBrowser/#/R-DME-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Drosophila melanogaster 15378 R-DME-6801342 https://reactome.org/PathwayBrowser/#/R-DME-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Drosophila melanogaster 15378 R-DME-6803771 https://reactome.org/PathwayBrowser/#/R-DME-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Drosophila melanogaster 15378 R-DME-6806967 https://reactome.org/PathwayBrowser/#/R-DME-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Drosophila melanogaster 15378 R-DME-6807557 https://reactome.org/PathwayBrowser/#/R-DME-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Drosophila melanogaster 15378 R-DME-6807826 https://reactome.org/PathwayBrowser/#/R-DME-6807826 LDHAL6B reduces PYR to LACT IEA Drosophila melanogaster 15378 R-DME-6808464 https://reactome.org/PathwayBrowser/#/R-DME-6808464 ALDH3B2 oxidises HXAL to PALM IEA Drosophila melanogaster 15378 R-DME-6808487 https://reactome.org/PathwayBrowser/#/R-DME-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 15378 R-DME-6808496 https://reactome.org/PathwayBrowser/#/R-DME-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 15378 R-DME-6813749 https://reactome.org/PathwayBrowser/#/R-DME-6813749 ALDH1A1 oxidises GA to DGA IEA Drosophila melanogaster 15378 R-DME-6814153 https://reactome.org/PathwayBrowser/#/R-DME-6814153 ADO oxidises 2AET to HTAU IEA Drosophila melanogaster 15378 R-DME-70333 https://reactome.org/PathwayBrowser/#/R-DME-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Drosophila melanogaster 15378 R-DME-70377 https://reactome.org/PathwayBrowser/#/R-DME-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Drosophila melanogaster 15378 R-DME-70420 https://reactome.org/PathwayBrowser/#/R-DME-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Drosophila melanogaster 15378 R-DME-70449 https://reactome.org/PathwayBrowser/#/R-DME-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Drosophila melanogaster 15378 R-DME-70467 https://reactome.org/PathwayBrowser/#/R-DME-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Drosophila melanogaster 15378 R-DME-70482 https://reactome.org/PathwayBrowser/#/R-DME-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Drosophila melanogaster 15378 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 15378 R-DME-70510 https://reactome.org/PathwayBrowser/#/R-DME-70510 LDH tetramer oxidises LACT to PYR IEA Drosophila melanogaster 15378 R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Drosophila melanogaster 15378 R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Drosophila melanogaster 15378 R-DME-70664 https://reactome.org/PathwayBrowser/#/R-DME-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 15378 R-DME-70670 https://reactome.org/PathwayBrowser/#/R-DME-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Drosophila melanogaster 15378 R-DME-70837 https://reactome.org/PathwayBrowser/#/R-DME-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Drosophila melanogaster 15378 R-DME-70885 https://reactome.org/PathwayBrowser/#/R-DME-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Drosophila melanogaster 15378 R-DME-70893 https://reactome.org/PathwayBrowser/#/R-DME-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 15378 R-DME-70938 https://reactome.org/PathwayBrowser/#/R-DME-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Drosophila melanogaster 15378 R-DME-70940 https://reactome.org/PathwayBrowser/#/R-DME-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Drosophila melanogaster 15378 R-DME-70941 https://reactome.org/PathwayBrowser/#/R-DME-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Drosophila melanogaster 15378 R-DME-70975 https://reactome.org/PathwayBrowser/#/R-DME-70975 CS acetylates OA to citrate IEA Drosophila melanogaster 15378 R-DME-70979 https://reactome.org/PathwayBrowser/#/R-DME-70979 MDH2 dimer dehydrogenates MAL IEA Drosophila melanogaster 15378 R-DME-71130 https://reactome.org/PathwayBrowser/#/R-DME-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Drosophila melanogaster 15378 R-DME-71164 https://reactome.org/PathwayBrowser/#/R-DME-71164 HGD dioxygenates homogentisate IEA Drosophila melanogaster 15378 R-DME-71181 https://reactome.org/PathwayBrowser/#/R-DME-71181 FAH cleaves 4FAA IEA Drosophila melanogaster 15378 R-DME-71200 https://reactome.org/PathwayBrowser/#/R-DME-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Drosophila melanogaster 15378 R-DME-71299 https://reactome.org/PathwayBrowser/#/R-DME-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Drosophila melanogaster 15378 R-DME-71401 https://reactome.org/PathwayBrowser/#/R-DME-71401 OGDH dimer decarboxylates 2-OG IEA Drosophila melanogaster 15378 R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 15378 R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 15378 R-DME-71707 https://reactome.org/PathwayBrowser/#/R-DME-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Drosophila melanogaster 15378 R-DME-71723 https://reactome.org/PathwayBrowser/#/R-DME-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Drosophila melanogaster 15378 R-DME-71849 https://reactome.org/PathwayBrowser/#/R-DME-71849 LDH tetramer reduces PYR to LACT IEA Drosophila melanogaster 15378 R-DME-73564 https://reactome.org/PathwayBrowser/#/R-DME-73564 UMPS dimer decarboxylates OMP to UMP IEA Drosophila melanogaster 15378 R-DME-73571 https://reactome.org/PathwayBrowser/#/R-DME-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Drosophila melanogaster 15378 R-DME-73573 https://reactome.org/PathwayBrowser/#/R-DME-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Drosophila melanogaster 15378 R-DME-73577 https://reactome.org/PathwayBrowser/#/R-DME-73577 CAD hexamer transforms L-Gln to CAP IEA Drosophila melanogaster 15378 R-DME-73585 https://reactome.org/PathwayBrowser/#/R-DME-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Drosophila melanogaster 15378 R-DME-73589 https://reactome.org/PathwayBrowser/#/R-DME-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Drosophila melanogaster 15378 R-DME-73591 https://reactome.org/PathwayBrowser/#/R-DME-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Drosophila melanogaster 15378 R-DME-73616 https://reactome.org/PathwayBrowser/#/R-DME-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Drosophila melanogaster 15378 R-DME-73618 https://reactome.org/PathwayBrowser/#/R-DME-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Drosophila melanogaster 15378 R-DME-73620 https://reactome.org/PathwayBrowser/#/R-DME-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Drosophila melanogaster 15378 R-DME-73647 https://reactome.org/PathwayBrowser/#/R-DME-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Drosophila melanogaster 15378 R-DME-73666 https://reactome.org/PathwayBrowser/#/R-DME-73666 dUTP + H2O => dUMP + pyrophosphate IEA Drosophila melanogaster 15378 R-DME-73792 https://reactome.org/PathwayBrowser/#/R-DME-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Drosophila melanogaster 15378 R-DME-73794 https://reactome.org/PathwayBrowser/#/R-DME-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Drosophila melanogaster 15378 R-DME-73805 https://reactome.org/PathwayBrowser/#/R-DME-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Drosophila melanogaster 15378 R-DME-73806 https://reactome.org/PathwayBrowser/#/R-DME-73806 AIR + CO2 => CAIR IEA Drosophila melanogaster 15378 R-DME-73810 https://reactome.org/PathwayBrowser/#/R-DME-73810 FGAM + ATP => AIR + ADP + Pi IEA Drosophila melanogaster 15378 R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 15378 R-DME-73813 https://reactome.org/PathwayBrowser/#/R-DME-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Drosophila melanogaster 15378 R-DME-73814 https://reactome.org/PathwayBrowser/#/R-DME-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Drosophila melanogaster 15378 R-DME-73912 https://reactome.org/PathwayBrowser/#/R-DME-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Drosophila melanogaster 15378 R-DME-73920 https://reactome.org/PathwayBrowser/#/R-DME-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Drosophila melanogaster 15378 R-DME-74255 https://reactome.org/PathwayBrowser/#/R-DME-74255 Guanine + H2O => Xanthine + NH4+ IEA Drosophila melanogaster 15378 R-DME-74723 https://reactome.org/PathwayBrowser/#/R-DME-74723 Endosome acidification IEA Drosophila melanogaster 15378 R-DME-74872 https://reactome.org/PathwayBrowser/#/R-DME-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 15378 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15378 R-DME-75872 https://reactome.org/PathwayBrowser/#/R-DME-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Drosophila melanogaster 15378 R-DME-75883 https://reactome.org/PathwayBrowser/#/R-DME-75883 DHRS7B reduces GO3P to HXDG3P IEA Drosophila melanogaster 15378 R-DME-75889 https://reactome.org/PathwayBrowser/#/R-DME-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Drosophila melanogaster 15378 R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 15378 R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 15378 R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 15378 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 15378 R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 15378 R-DME-77283 https://reactome.org/PathwayBrowser/#/R-DME-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Drosophila melanogaster 15378 R-DME-77303 https://reactome.org/PathwayBrowser/#/R-DME-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Drosophila melanogaster 15378 R-DME-8847579 https://reactome.org/PathwayBrowser/#/R-DME-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15378 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 15378 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 15378 R-DME-8862137 https://reactome.org/PathwayBrowser/#/R-DME-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Drosophila melanogaster 15378 R-DME-8863494 https://reactome.org/PathwayBrowser/#/R-DME-8863494 ASICs bind STOML3, (STOM) IEA Drosophila melanogaster 15378 R-DME-8866601 https://reactome.org/PathwayBrowser/#/R-DME-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Drosophila melanogaster 15378 R-DME-8869606 https://reactome.org/PathwayBrowser/#/R-DME-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 15378 R-DME-8869607 https://reactome.org/PathwayBrowser/#/R-DME-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 15378 R-DME-8869627 https://reactome.org/PathwayBrowser/#/R-DME-8869627 NMRK2 phosphorylates NR to yield NMN IEA Drosophila melanogaster 15378 R-DME-8869633 https://reactome.org/PathwayBrowser/#/R-DME-8869633 NMRK1 phosphorylates NR to yield NMN IEA Drosophila melanogaster 15378 R-DME-8875623 https://reactome.org/PathwayBrowser/#/R-DME-8875623 SLC25A18,22 import L-Glu, H+ IEA Drosophila melanogaster 15378 R-DME-8878914 https://reactome.org/PathwayBrowser/#/R-DME-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Drosophila melanogaster 15378 R-DME-888548 https://reactome.org/PathwayBrowser/#/R-DME-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Drosophila melanogaster 15378 R-DME-888572 https://reactome.org/PathwayBrowser/#/R-DME-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Drosophila melanogaster 15378 R-DME-888577 https://reactome.org/PathwayBrowser/#/R-DME-888577 Synthesis of GABA by GAD2 IEA Drosophila melanogaster 15378 R-DME-8933635 https://reactome.org/PathwayBrowser/#/R-DME-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Drosophila melanogaster 15378 R-DME-8936442 https://reactome.org/PathwayBrowser/#/R-DME-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Drosophila melanogaster 15378 R-DME-8952873 https://reactome.org/PathwayBrowser/#/R-DME-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Drosophila melanogaster 15378 R-DME-8955030 https://reactome.org/PathwayBrowser/#/R-DME-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 15378 R-DME-8955760 https://reactome.org/PathwayBrowser/#/R-DME-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Drosophila melanogaster 15378 R-DME-8959510 https://reactome.org/PathwayBrowser/#/R-DME-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Drosophila melanogaster 15378 R-DME-9009950 https://reactome.org/PathwayBrowser/#/R-DME-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Drosophila melanogaster 15378 R-DME-9011595 https://reactome.org/PathwayBrowser/#/R-DME-9011595 GSTZ1 dimer dehalogenates DCA IEA Drosophila melanogaster 15378 R-DME-9012016 https://reactome.org/PathwayBrowser/#/R-DME-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Drosophila melanogaster 15378 R-DME-9012036 https://reactome.org/PathwayBrowser/#/R-DME-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 15378 R-DME-9027043 https://reactome.org/PathwayBrowser/#/R-DME-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Drosophila melanogaster 15378 R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 15378 R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 15378 R-DME-917841 https://reactome.org/PathwayBrowser/#/R-DME-917841 Acidification of Tf:TfR1 containing endosome IEA Drosophila melanogaster 15378 R-DME-917979 https://reactome.org/PathwayBrowser/#/R-DME-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Drosophila melanogaster 15378 R-DME-9620103 https://reactome.org/PathwayBrowser/#/R-DME-9620103 ALDH2 transforms GTN to NO IEA Drosophila melanogaster 15378 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-DME-9650165 https://reactome.org/PathwayBrowser/#/R-DME-9650165 ASIC trimers bind H+ IEA Drosophila melanogaster 15378 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 15378 R-DME-9705714 https://reactome.org/PathwayBrowser/#/R-DME-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Drosophila melanogaster 15378 R-DME-9709098 https://reactome.org/PathwayBrowser/#/R-DME-9709098 DHFR dimer reduces FOLA to DHF IEA Drosophila melanogaster 15378 R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 15378 R-DME-9727349 https://reactome.org/PathwayBrowser/#/R-DME-9727349 XDH dehydrogenates xanthine to form urate IEA Drosophila melanogaster 15378 R-DME-9731661 https://reactome.org/PathwayBrowser/#/R-DME-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Drosophila melanogaster 15378 R-DME-9748945 https://reactome.org/PathwayBrowser/#/R-DME-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Drosophila melanogaster 15378 R-DME-9748957 https://reactome.org/PathwayBrowser/#/R-DME-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Drosophila melanogaster 15378 R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 15378 R-DME-9749609 https://reactome.org/PathwayBrowser/#/R-DME-9749609 BCHE hydrolyzes ASA- IEA Drosophila melanogaster 15378 R-DME-9749647 https://reactome.org/PathwayBrowser/#/R-DME-9749647 CES2 hydrolyzes ASA- IEA Drosophila melanogaster 15378 R-DME-9749792 https://reactome.org/PathwayBrowser/#/R-DME-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Drosophila melanogaster 15378 R-DME-9753285 https://reactome.org/PathwayBrowser/#/R-DME-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Drosophila melanogaster 15378 R-DME-975629 https://reactome.org/PathwayBrowser/#/R-DME-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 15378 R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 15378 R-DME-9758682 https://reactome.org/PathwayBrowser/#/R-DME-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Drosophila melanogaster 15378 R-DME-9759259 https://reactome.org/PathwayBrowser/#/R-DME-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Drosophila melanogaster 15378 R-DME-9760094 https://reactome.org/PathwayBrowser/#/R-DME-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Drosophila melanogaster 15378 R-DME-977348 https://reactome.org/PathwayBrowser/#/R-DME-977348 PHGDH tetramer dehydrogenates 3PG IEA Drosophila melanogaster 15378 R-DME-9794270 https://reactome.org/PathwayBrowser/#/R-DME-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Drosophila melanogaster 15378 R-DME-9837337 https://reactome.org/PathwayBrowser/#/R-DME-9837337 DCAKD phosphorylates DP-CoA IEA Drosophila melanogaster 15378 R-DME-9843721 https://reactome.org/PathwayBrowser/#/R-DME-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Drosophila melanogaster 15378 R-DME-9845516 https://reactome.org/PathwayBrowser/#/R-DME-9845516 B3GALT4 transfers Gal to gangliosides IEA Drosophila melanogaster 15378 R-DME-9846477 https://reactome.org/PathwayBrowser/#/R-DME-9846477 A4GALT transfers galactose to LacCer IEA Drosophila melanogaster 15378 R-DME-9846501 https://reactome.org/PathwayBrowser/#/R-DME-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Drosophila melanogaster 15378 R-DME-9851347 https://reactome.org/PathwayBrowser/#/R-DME-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Drosophila melanogaster 15378 R-DME-9853499 https://reactome.org/PathwayBrowser/#/R-DME-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 15378 R-DME-9856871 https://reactome.org/PathwayBrowser/#/R-DME-9856871 MDH1 reduces OA IEA Drosophila melanogaster 15378 R-DME-9861616 https://reactome.org/PathwayBrowser/#/R-DME-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 15378 R-DME-9861660 https://reactome.org/PathwayBrowser/#/R-DME-9861660 ME1 tetramer decarboxylates OA to PYR IEA Drosophila melanogaster 15378 R-DME-9861734 https://reactome.org/PathwayBrowser/#/R-DME-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Drosophila melanogaster 15378 R-DRE-111524 https://reactome.org/PathwayBrowser/#/R-DRE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Danio rerio 15378 R-DRE-1222376 https://reactome.org/PathwayBrowser/#/R-DRE-1222376 NOX2 generates superoxide from oxygen IEA Danio rerio 15378 R-DRE-1222516 https://reactome.org/PathwayBrowser/#/R-DRE-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Danio rerio 15378 R-DRE-1236967 https://reactome.org/PathwayBrowser/#/R-DRE-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Danio rerio 15378 R-DRE-1237047 https://reactome.org/PathwayBrowser/#/R-DRE-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Danio rerio 15378 R-DRE-1237059 https://reactome.org/PathwayBrowser/#/R-DRE-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Danio rerio 15378 R-DRE-1237129 https://reactome.org/PathwayBrowser/#/R-DRE-1237129 Acireductone is created IEA Danio rerio 15378 R-DRE-1237325 https://reactome.org/PathwayBrowser/#/R-DRE-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Danio rerio 15378 R-DRE-1247668 https://reactome.org/PathwayBrowser/#/R-DRE-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Danio rerio 15378 R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 15378 R-DRE-140359 https://reactome.org/PathwayBrowser/#/R-DRE-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Danio rerio 15378 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 15378 R-DRE-1475017 https://reactome.org/PathwayBrowser/#/R-DRE-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Danio rerio 15378 R-DRE-1475022 https://reactome.org/PathwayBrowser/#/R-DRE-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Danio rerio 15378 R-DRE-1475025 https://reactome.org/PathwayBrowser/#/R-DRE-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Danio rerio 15378 R-DRE-1475026 https://reactome.org/PathwayBrowser/#/R-DRE-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Danio rerio 15378 R-DRE-1475028 https://reactome.org/PathwayBrowser/#/R-DRE-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Danio rerio 15378 R-DRE-1475032 https://reactome.org/PathwayBrowser/#/R-DRE-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Danio rerio 15378 R-DRE-1475435 https://reactome.org/PathwayBrowser/#/R-DRE-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Danio rerio 15378 R-DRE-1475436 https://reactome.org/PathwayBrowser/#/R-DRE-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Danio rerio 15378 R-DRE-1497869 https://reactome.org/PathwayBrowser/#/R-DRE-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Danio rerio 15378 R-DRE-1562626 https://reactome.org/PathwayBrowser/#/R-DRE-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Danio rerio 15378 R-DRE-156526 https://reactome.org/PathwayBrowser/#/R-DRE-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Danio rerio 15378 R-DRE-158609 https://reactome.org/PathwayBrowser/#/R-DRE-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Danio rerio 15378 R-DRE-1606273 https://reactome.org/PathwayBrowser/#/R-DRE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Danio rerio 15378 R-DRE-1606288 https://reactome.org/PathwayBrowser/#/R-DRE-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Danio rerio 15378 R-DRE-1614605 https://reactome.org/PathwayBrowser/#/R-DRE-1614605 Persulfide sulfur is dioxygenated IEA Danio rerio 15378 R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 15378 R-DRE-163217 https://reactome.org/PathwayBrowser/#/R-DRE-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Danio rerio 15378 R-DRE-1638104 https://reactome.org/PathwayBrowser/#/R-DRE-1638104 UGCG transfers glucose to ceramide IEA Danio rerio 15378 R-DRE-164651 https://reactome.org/PathwayBrowser/#/R-DRE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Danio rerio 15378 R-DRE-164834 https://reactome.org/PathwayBrowser/#/R-DRE-164834 Enzyme-bound ATP is released IEA Danio rerio 15378 R-DRE-1655453 https://reactome.org/PathwayBrowser/#/R-DRE-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Danio rerio 15378 R-DRE-170026 https://reactome.org/PathwayBrowser/#/R-DRE-170026 Protons are translocated from the intermembrane space to the matrix IEA Danio rerio 15378 R-DRE-173597 https://reactome.org/PathwayBrowser/#/R-DRE-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Danio rerio 15378 R-DRE-174389 https://reactome.org/PathwayBrowser/#/R-DRE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Danio rerio 15378 R-DRE-174392 https://reactome.org/PathwayBrowser/#/R-DRE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Danio rerio 15378 R-DRE-189421 https://reactome.org/PathwayBrowser/#/R-DRE-189421 CPO transforms COPRO3 to PPGEN9 IEA Danio rerio 15378 R-DRE-189425 https://reactome.org/PathwayBrowser/#/R-DRE-189425 UROD decarboxylates URO3 to COPRO3 IEA Danio rerio 15378 R-DRE-189439 https://reactome.org/PathwayBrowser/#/R-DRE-189439 ALAD condenses 2 dALAs to form PBG IEA Danio rerio 15378 R-DRE-189442 https://reactome.org/PathwayBrowser/#/R-DRE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Danio rerio 15378 R-DRE-189465 https://reactome.org/PathwayBrowser/#/R-DRE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Danio rerio 15378 R-DRE-190182 https://reactome.org/PathwayBrowser/#/R-DRE-190182 UROD decarboxylates URO1 to COPRO1 IEA Danio rerio 15378 R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 15378 R-DRE-191352 https://reactome.org/PathwayBrowser/#/R-DRE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Danio rerio 15378 R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 15378 R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 15378 R-DRE-192097 https://reactome.org/PathwayBrowser/#/R-DRE-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Danio rerio 15378 R-DRE-192157 https://reactome.org/PathwayBrowser/#/R-DRE-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Danio rerio 15378 R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 15378 R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 15378 R-DRE-193064 https://reactome.org/PathwayBrowser/#/R-DRE-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Danio rerio 15378 R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 15378 R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 15378 R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 15378 R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 15378 R-DRE-193073 https://reactome.org/PathwayBrowser/#/R-DRE-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Danio rerio 15378 R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 15378 R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 15378 R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 15378 R-DRE-193709 https://reactome.org/PathwayBrowser/#/R-DRE-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Danio rerio 15378 R-DRE-193789 https://reactome.org/PathwayBrowser/#/R-DRE-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Danio rerio 15378 R-DRE-193816 https://reactome.org/PathwayBrowser/#/R-DRE-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Danio rerio 15378 R-DRE-193845 https://reactome.org/PathwayBrowser/#/R-DRE-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Danio rerio 15378 R-DRE-194023 https://reactome.org/PathwayBrowser/#/R-DRE-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Danio rerio 15378 R-DRE-194632 https://reactome.org/PathwayBrowser/#/R-DRE-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Danio rerio 15378 R-DRE-194641 https://reactome.org/PathwayBrowser/#/R-DRE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15378 R-DRE-194642 https://reactome.org/PathwayBrowser/#/R-DRE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Danio rerio 15378 R-DRE-194669 https://reactome.org/PathwayBrowser/#/R-DRE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15378 R-DRE-194674 https://reactome.org/PathwayBrowser/#/R-DRE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Danio rerio 15378 R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 15378 R-DRE-194689 https://reactome.org/PathwayBrowser/#/R-DRE-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15378 R-DRE-194698 https://reactome.org/PathwayBrowser/#/R-DRE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Danio rerio 15378 R-DRE-194718 https://reactome.org/PathwayBrowser/#/R-DRE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Danio rerio 15378 R-DRE-195664 https://reactome.org/PathwayBrowser/#/R-DRE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Danio rerio 15378 R-DRE-196060 https://reactome.org/PathwayBrowser/#/R-DRE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Danio rerio 15378 R-DRE-196350 https://reactome.org/PathwayBrowser/#/R-DRE-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Danio rerio 15378 R-DRE-196372 https://reactome.org/PathwayBrowser/#/R-DRE-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Danio rerio 15378 R-DRE-196402 https://reactome.org/PathwayBrowser/#/R-DRE-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Danio rerio 15378 R-DRE-196417 https://reactome.org/PathwayBrowser/#/R-DRE-196417 Reduction of desmosterol to cholesterol IEA Danio rerio 15378 R-DRE-196753 https://reactome.org/PathwayBrowser/#/R-DRE-196753 2xPPCS ligates PPanK with Cys IEA Danio rerio 15378 R-DRE-196754 https://reactome.org/PathwayBrowser/#/R-DRE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Danio rerio 15378 R-DRE-196773 https://reactome.org/PathwayBrowser/#/R-DRE-196773 COASY phosphorylates DP-CoA IEA Danio rerio 15378 R-DRE-196929 https://reactome.org/PathwayBrowser/#/R-DRE-196929 FLAD1 phosphorylates FMN IEA Danio rerio 15378 R-DRE-196955 https://reactome.org/PathwayBrowser/#/R-DRE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Danio rerio 15378 R-DRE-197186 https://reactome.org/PathwayBrowser/#/R-DRE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Danio rerio 15378 R-DRE-197963 https://reactome.org/PathwayBrowser/#/R-DRE-197963 DHFR2 reduces FOLA to DHF IEA Danio rerio 15378 R-DRE-197972 https://reactome.org/PathwayBrowser/#/R-DRE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Danio rerio 15378 R-DRE-198824 https://reactome.org/PathwayBrowser/#/R-DRE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Danio rerio 15378 R-DRE-199203 https://reactome.org/PathwayBrowser/#/R-DRE-199203 PANK1/3 phosphorylate PanK IEA Danio rerio 15378 R-DRE-200644 https://reactome.org/PathwayBrowser/#/R-DRE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Danio rerio 15378 R-DRE-200676 https://reactome.org/PathwayBrowser/#/R-DRE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Danio rerio 15378 R-DRE-200718 https://reactome.org/PathwayBrowser/#/R-DRE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Danio rerio 15378 R-DRE-204617 https://reactome.org/PathwayBrowser/#/R-DRE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Danio rerio 15378 R-DRE-204647 https://reactome.org/PathwayBrowser/#/R-DRE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Danio rerio 15378 R-DRE-204662 https://reactome.org/PathwayBrowser/#/R-DRE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Danio rerio 15378 R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 15378 R-DRE-209821 https://reactome.org/PathwayBrowser/#/R-DRE-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Danio rerio 15378 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 15378 R-DRE-210404 https://reactome.org/PathwayBrowser/#/R-DRE-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Danio rerio 15378 R-DRE-211873 https://reactome.org/PathwayBrowser/#/R-DRE-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Danio rerio 15378 R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 15378 R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 15378 R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 15378 R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 15378 R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 15378 R-DRE-211923 https://reactome.org/PathwayBrowser/#/R-DRE-211923 CYP26C1 4-hydroxylates 9cRA IEA Danio rerio 15378 R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 15378 R-DRE-211950 https://reactome.org/PathwayBrowser/#/R-DRE-211950 CYP24A1 24-hydroxylates CTL IEA Danio rerio 15378 R-DRE-211951 https://reactome.org/PathwayBrowser/#/R-DRE-211951 CYP1B1 4-hydroxylates EST17b IEA Danio rerio 15378 R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 15378 R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 15378 R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 15378 R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 15378 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 15378 R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 15378 R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 15378 R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 15378 R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 15378 R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 15378 R-DRE-2161187 https://reactome.org/PathwayBrowser/#/R-DRE-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Danio rerio 15378 R-DRE-2161651 https://reactome.org/PathwayBrowser/#/R-DRE-2161651 PGE2 is converted to PGF2a by CBR1 IEA Danio rerio 15378 R-DRE-2161745 https://reactome.org/PathwayBrowser/#/R-DRE-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Danio rerio 15378 R-DRE-2161779 https://reactome.org/PathwayBrowser/#/R-DRE-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Danio rerio 15378 R-DRE-2161792 https://reactome.org/PathwayBrowser/#/R-DRE-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Danio rerio 15378 R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Danio rerio 15378 R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 15378 R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio 15378 R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Danio rerio 15378 R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 15378 R-DRE-2161951 https://reactome.org/PathwayBrowser/#/R-DRE-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Danio rerio 15378 R-DRE-2162078 https://reactome.org/PathwayBrowser/#/R-DRE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Danio rerio 15378 R-DRE-2162186 https://reactome.org/PathwayBrowser/#/R-DRE-2162186 COQ3 methylates DeMQ10H2 IEA Danio rerio 15378 R-DRE-2162188 https://reactome.org/PathwayBrowser/#/R-DRE-2162188 COQ5 methylates MDMQ10H2 IEA Danio rerio 15378 R-DRE-2162193 https://reactome.org/PathwayBrowser/#/R-DRE-2162193 COQ3 methylates DHDB IEA Danio rerio 15378 R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 15378 R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 15378 R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 15378 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 15378 R-DRE-2395512 https://reactome.org/PathwayBrowser/#/R-DRE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Danio rerio 15378 R-DRE-2395517 https://reactome.org/PathwayBrowser/#/R-DRE-2395517 NADPH transfers electrons to FDXR IEA Danio rerio 15378 R-DRE-2395818 https://reactome.org/PathwayBrowser/#/R-DRE-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Danio rerio 15378 R-DRE-2395849 https://reactome.org/PathwayBrowser/#/R-DRE-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Danio rerio 15378 R-DRE-2395872 https://reactome.org/PathwayBrowser/#/R-DRE-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Danio rerio 15378 R-DRE-2395873 https://reactome.org/PathwayBrowser/#/R-DRE-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Danio rerio 15378 R-DRE-2395879 https://reactome.org/PathwayBrowser/#/R-DRE-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Danio rerio 15378 R-DRE-2395965 https://reactome.org/PathwayBrowser/#/R-DRE-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Danio rerio 15378 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 15378 R-DRE-2454081 https://reactome.org/PathwayBrowser/#/R-DRE-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Danio rerio 15378 R-DRE-2464822 https://reactome.org/PathwayBrowser/#/R-DRE-2464822 RDH12 reduces atRAL to atROL IEA Danio rerio 15378 R-DRE-2465940 https://reactome.org/PathwayBrowser/#/R-DRE-2465940 atRAL is reduced to atROL IEA Danio rerio 15378 R-DRE-2509793 https://reactome.org/PathwayBrowser/#/R-DRE-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Danio rerio 15378 R-DRE-2509816 https://reactome.org/PathwayBrowser/#/R-DRE-2509816 NUDT16 hydrolyses IDP to IMP IEA Danio rerio 15378 R-DRE-2509827 https://reactome.org/PathwayBrowser/#/R-DRE-2509827 ITPA hydrolyses ITP to IMP IEA Danio rerio 15378 R-DRE-2509831 https://reactome.org/PathwayBrowser/#/R-DRE-2509831 ITPA hydrolyses XTP to XMP IEA Danio rerio 15378 R-DRE-2509838 https://reactome.org/PathwayBrowser/#/R-DRE-2509838 ITPA hydrolyses dITP to dIMP IEA Danio rerio 15378 R-DRE-2534378 https://reactome.org/PathwayBrowser/#/R-DRE-2534378 Hv1 Mediated H+ Permeability IEA Danio rerio 15378 R-DRE-264615 https://reactome.org/PathwayBrowser/#/R-DRE-264615 Loading of acetylcholine in synaptic vesicles IEA Danio rerio 15378 R-DRE-2671885 https://reactome.org/PathwayBrowser/#/R-DRE-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Danio rerio 15378 R-DRE-2730692 https://reactome.org/PathwayBrowser/#/R-DRE-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Danio rerio 15378 R-DRE-2855252 https://reactome.org/PathwayBrowser/#/R-DRE-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Danio rerio 15378 R-DRE-3095889 https://reactome.org/PathwayBrowser/#/R-DRE-3095889 MMACHC dealkylates RCbl IEA Danio rerio 15378 R-DRE-3149519 https://reactome.org/PathwayBrowser/#/R-DRE-3149519 MMACHC decyanates CNCbl IEA Danio rerio 15378 R-DRE-3299680 https://reactome.org/PathwayBrowser/#/R-DRE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Danio rerio 15378 R-DRE-3299682 https://reactome.org/PathwayBrowser/#/R-DRE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Danio rerio 15378 R-DRE-3299691 https://reactome.org/PathwayBrowser/#/R-DRE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Danio rerio 15378 R-DRE-352182 https://reactome.org/PathwayBrowser/#/R-DRE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Danio rerio 15378 R-DRE-372448 https://reactome.org/PathwayBrowser/#/R-DRE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Danio rerio 15378 R-DRE-3777112 https://reactome.org/PathwayBrowser/#/R-DRE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Danio rerio 15378 R-DRE-380608 https://reactome.org/PathwayBrowser/#/R-DRE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Danio rerio 15378 R-DRE-389540 https://reactome.org/PathwayBrowser/#/R-DRE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 15378 R-DRE-389550 https://reactome.org/PathwayBrowser/#/R-DRE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 15378 R-DRE-389609 https://reactome.org/PathwayBrowser/#/R-DRE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Danio rerio 15378 R-DRE-389826 https://reactome.org/PathwayBrowser/#/R-DRE-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Danio rerio 15378 R-DRE-390438 https://reactome.org/PathwayBrowser/#/R-DRE-390438 FAR2 reduces PalmCoA to HXOL IEA Danio rerio 15378 R-DRE-418365 https://reactome.org/PathwayBrowser/#/R-DRE-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Danio rerio 15378 R-DRE-425983 https://reactome.org/PathwayBrowser/#/R-DRE-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Danio rerio 15378 R-DRE-425994 https://reactome.org/PathwayBrowser/#/R-DRE-425994 Na+/H+ exchanger transport (at cell membrane) IEA Danio rerio 15378 R-DRE-426015 https://reactome.org/PathwayBrowser/#/R-DRE-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Danio rerio 15378 R-DRE-426043 https://reactome.org/PathwayBrowser/#/R-DRE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Danio rerio 15378 R-DRE-427555 https://reactome.org/PathwayBrowser/#/R-DRE-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Danio rerio 15378 R-DRE-427910 https://reactome.org/PathwayBrowser/#/R-DRE-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Danio rerio 15378 R-DRE-427998 https://reactome.org/PathwayBrowser/#/R-DRE-427998 Proton-coupled di- and tri-peptide cotransport IEA Danio rerio 15378 R-DRE-428015 https://reactome.org/PathwayBrowser/#/R-DRE-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Danio rerio 15378 R-DRE-428052 https://reactome.org/PathwayBrowser/#/R-DRE-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Danio rerio 15378 R-DRE-428127 https://reactome.org/PathwayBrowser/#/R-DRE-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Danio rerio 15378 R-DRE-428185 https://reactome.org/PathwayBrowser/#/R-DRE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Danio rerio 15378 R-DRE-428259 https://reactome.org/PathwayBrowser/#/R-DRE-428259 DEGS1 dehydrogenates dihydroceramide IEA Danio rerio 15378 R-DRE-428585 https://reactome.org/PathwayBrowser/#/R-DRE-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Danio rerio 15378 R-DRE-428625 https://reactome.org/PathwayBrowser/#/R-DRE-428625 Vesicular inhibitory amino acid transport IEA Danio rerio 15378 R-DRE-429157 https://reactome.org/PathwayBrowser/#/R-DRE-429157 ABCC4 accumulation of dense granule contents IEA Danio rerio 15378 R-DRE-429698 https://reactome.org/PathwayBrowser/#/R-DRE-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Danio rerio 15378 R-DRE-429714 https://reactome.org/PathwayBrowser/#/R-DRE-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Danio rerio 15378 R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 15378 R-DRE-434650 https://reactome.org/PathwayBrowser/#/R-DRE-434650 MATEs mediate extrusion of xenobiotics IEA Danio rerio 15378 R-DRE-435171 https://reactome.org/PathwayBrowser/#/R-DRE-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Danio rerio 15378 R-DRE-435349 https://reactome.org/PathwayBrowser/#/R-DRE-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Danio rerio 15378 R-DRE-444393 https://reactome.org/PathwayBrowser/#/R-DRE-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Danio rerio 15378 R-DRE-444419 https://reactome.org/PathwayBrowser/#/R-DRE-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Danio rerio 15378 R-DRE-446277 https://reactome.org/PathwayBrowser/#/R-DRE-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Danio rerio 15378 R-DRE-446278 https://reactome.org/PathwayBrowser/#/R-DRE-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Danio rerio 15378 R-DRE-450971 https://reactome.org/PathwayBrowser/#/R-DRE-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Danio rerio 15378 R-DRE-469659 https://reactome.org/PathwayBrowser/#/R-DRE-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Danio rerio 15378 R-DRE-504054 https://reactome.org/PathwayBrowser/#/R-DRE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Danio rerio 15378 R-DRE-508369 https://reactome.org/PathwayBrowser/#/R-DRE-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Danio rerio 15378 R-DRE-508473 https://reactome.org/PathwayBrowser/#/R-DRE-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Danio rerio 15378 R-DRE-514604 https://reactome.org/PathwayBrowser/#/R-DRE-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Danio rerio 15378 R-DRE-5218841 https://reactome.org/PathwayBrowser/#/R-DRE-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Danio rerio 15378 R-DRE-5340130 https://reactome.org/PathwayBrowser/#/R-DRE-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Danio rerio 15378 R-DRE-5340226 https://reactome.org/PathwayBrowser/#/R-DRE-5340226 CYGB dioxygenates NO IEA Danio rerio 15378 R-DRE-5362518 https://reactome.org/PathwayBrowser/#/R-DRE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Danio rerio 15378 R-DRE-5362522 https://reactome.org/PathwayBrowser/#/R-DRE-5362522 ALDHs oxidise atRAL to atRA IEA Danio rerio 15378 R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 15378 R-DRE-5362564 https://reactome.org/PathwayBrowser/#/R-DRE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Danio rerio 15378 R-DRE-5362721 https://reactome.org/PathwayBrowser/#/R-DRE-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Danio rerio 15378 R-DRE-5419165 https://reactome.org/PathwayBrowser/#/R-DRE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Danio rerio 15378 R-DRE-5423637 https://reactome.org/PathwayBrowser/#/R-DRE-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Danio rerio 15378 R-DRE-5423647 https://reactome.org/PathwayBrowser/#/R-DRE-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Danio rerio 15378 R-DRE-5423664 https://reactome.org/PathwayBrowser/#/R-DRE-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Danio rerio 15378 R-DRE-5423672 https://reactome.org/PathwayBrowser/#/R-DRE-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Danio rerio 15378 R-DRE-5423678 https://reactome.org/PathwayBrowser/#/R-DRE-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Danio rerio 15378 R-DRE-548818 https://reactome.org/PathwayBrowser/#/R-DRE-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Danio rerio 15378 R-DRE-5602295 https://reactome.org/PathwayBrowser/#/R-DRE-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Danio rerio 15378 R-DRE-5652172 https://reactome.org/PathwayBrowser/#/R-DRE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Danio rerio 15378 R-DRE-5661240 https://reactome.org/PathwayBrowser/#/R-DRE-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Danio rerio 15378 R-DRE-5661256 https://reactome.org/PathwayBrowser/#/R-DRE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Danio rerio 15378 R-DRE-5661290 https://reactome.org/PathwayBrowser/#/R-DRE-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Danio rerio 15378 R-DRE-5668629 https://reactome.org/PathwayBrowser/#/R-DRE-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Danio rerio 15378 R-DRE-5668718 https://reactome.org/PathwayBrowser/#/R-DRE-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 15378 R-DRE-5668731 https://reactome.org/PathwayBrowser/#/R-DRE-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 15378 R-DRE-5678327 https://reactome.org/PathwayBrowser/#/R-DRE-5678327 MIOX oxidises Ins to GlcA IEA Danio rerio 15378 R-DRE-5690565 https://reactome.org/PathwayBrowser/#/R-DRE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Danio rerio 15378 R-DRE-5691107 https://reactome.org/PathwayBrowser/#/R-DRE-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Danio rerio 15378 R-DRE-5692237 https://reactome.org/PathwayBrowser/#/R-DRE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Danio rerio 15378 R-DRE-5692261 https://reactome.org/PathwayBrowser/#/R-DRE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Danio rerio 15378 R-DRE-5692283 https://reactome.org/PathwayBrowser/#/R-DRE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Danio rerio 15378 R-DRE-5693347 https://reactome.org/PathwayBrowser/#/R-DRE-5693347 CRYM reduces P2C to PPCA IEA Danio rerio 15378 R-DRE-5693691 https://reactome.org/PathwayBrowser/#/R-DRE-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Danio rerio 15378 R-DRE-5694018 https://reactome.org/PathwayBrowser/#/R-DRE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Danio rerio 15378 R-DRE-5694462 https://reactome.org/PathwayBrowser/#/R-DRE-5694462 ABHD6,12 hydrolyse 3AG IEA Danio rerio 15378 R-DRE-5696080 https://reactome.org/PathwayBrowser/#/R-DRE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Danio rerio 15378 R-DRE-5696091 https://reactome.org/PathwayBrowser/#/R-DRE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Danio rerio 15378 R-DRE-5696101 https://reactome.org/PathwayBrowser/#/R-DRE-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Danio rerio 15378 R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 15378 R-DRE-5696457 https://reactome.org/PathwayBrowser/#/R-DRE-5696457 BDH2 dehydrogenates 3HBA IEA Danio rerio 15378 R-DRE-5696822 https://reactome.org/PathwayBrowser/#/R-DRE-5696822 AKR1B15 reduces EST17b to E1 IEA Danio rerio 15378 R-DRE-5696838 https://reactome.org/PathwayBrowser/#/R-DRE-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Danio rerio 15378 R-DRE-597628 https://reactome.org/PathwayBrowser/#/R-DRE-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Danio rerio 15378 R-DRE-6783221 https://reactome.org/PathwayBrowser/#/R-DRE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Danio rerio 15378 R-DRE-6783939 https://reactome.org/PathwayBrowser/#/R-DRE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 15378 R-DRE-6783955 https://reactome.org/PathwayBrowser/#/R-DRE-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 15378 R-DRE-6784399 https://reactome.org/PathwayBrowser/#/R-DRE-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Danio rerio 15378 R-DRE-6785933 https://reactome.org/PathwayBrowser/#/R-DRE-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Danio rerio 15378 R-DRE-6786239 https://reactome.org/PathwayBrowser/#/R-DRE-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Danio rerio 15378 R-DRE-6786720 https://reactome.org/PathwayBrowser/#/R-DRE-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Danio rerio 15378 R-DRE-6787642 https://reactome.org/PathwayBrowser/#/R-DRE-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Danio rerio 15378 R-DRE-6788999 https://reactome.org/PathwayBrowser/#/R-DRE-6788999 HV1-mediated H+ transfer IEA Danio rerio 15378 R-DRE-6789092 https://reactome.org/PathwayBrowser/#/R-DRE-6789092 NOX2 generates superoxide anion from oxygen IEA Danio rerio 15378 R-DRE-6793590 https://reactome.org/PathwayBrowser/#/R-DRE-6793590 LIPT2 transfers octanoyl group to GCSH IEA Danio rerio 15378 R-DRE-6793591 https://reactome.org/PathwayBrowser/#/R-DRE-6793591 LIAS synthesizes lipoyl-GCSH IEA Danio rerio 15378 R-DRE-6799495 https://reactome.org/PathwayBrowser/#/R-DRE-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Danio rerio 15378 R-DRE-6801342 https://reactome.org/PathwayBrowser/#/R-DRE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio 15378 R-DRE-6806647 https://reactome.org/PathwayBrowser/#/R-DRE-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Danio rerio 15378 R-DRE-6806831 https://reactome.org/PathwayBrowser/#/R-DRE-6806831 CYB5Rs reduce MetHb to HbA IEA Danio rerio 15378 R-DRE-6806967 https://reactome.org/PathwayBrowser/#/R-DRE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Danio rerio 15378 R-DRE-6807053 https://reactome.org/PathwayBrowser/#/R-DRE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Danio rerio 15378 R-DRE-6807055 https://reactome.org/PathwayBrowser/#/R-DRE-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Danio rerio 15378 R-DRE-6807064 https://reactome.org/PathwayBrowser/#/R-DRE-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Danio rerio 15378 R-DRE-6807826 https://reactome.org/PathwayBrowser/#/R-DRE-6807826 LDHAL6B reduces PYR to LACT IEA Danio rerio 15378 R-DRE-6808464 https://reactome.org/PathwayBrowser/#/R-DRE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Danio rerio 15378 R-DRE-6808496 https://reactome.org/PathwayBrowser/#/R-DRE-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Danio rerio 15378 R-DRE-6809264 https://reactome.org/PathwayBrowser/#/R-DRE-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Danio rerio 15378 R-DRE-6809287 https://reactome.org/PathwayBrowser/#/R-DRE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Danio rerio 15378 R-DRE-6809810 https://reactome.org/PathwayBrowser/#/R-DRE-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Danio rerio 15378 R-DRE-6810594 https://reactome.org/PathwayBrowser/#/R-DRE-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Danio rerio 15378 R-DRE-6814153 https://reactome.org/PathwayBrowser/#/R-DRE-6814153 ADO oxidises 2AET to HTAU IEA Danio rerio 15378 R-DRE-70420 https://reactome.org/PathwayBrowser/#/R-DRE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Danio rerio 15378 R-DRE-70449 https://reactome.org/PathwayBrowser/#/R-DRE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Danio rerio 15378 R-DRE-70467 https://reactome.org/PathwayBrowser/#/R-DRE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Danio rerio 15378 R-DRE-70482 https://reactome.org/PathwayBrowser/#/R-DRE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Danio rerio 15378 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 15378 R-DRE-70510 https://reactome.org/PathwayBrowser/#/R-DRE-70510 LDH tetramer oxidises LACT to PYR IEA Danio rerio 15378 R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Danio rerio 15378 R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Danio rerio 15378 R-DRE-70664 https://reactome.org/PathwayBrowser/#/R-DRE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 15378 R-DRE-70679 https://reactome.org/PathwayBrowser/#/R-DRE-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Danio rerio 15378 R-DRE-70837 https://reactome.org/PathwayBrowser/#/R-DRE-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Danio rerio 15378 R-DRE-70885 https://reactome.org/PathwayBrowser/#/R-DRE-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Danio rerio 15378 R-DRE-70893 https://reactome.org/PathwayBrowser/#/R-DRE-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Danio rerio 15378 R-DRE-70906 https://reactome.org/PathwayBrowser/#/R-DRE-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Danio rerio 15378 R-DRE-70938 https://reactome.org/PathwayBrowser/#/R-DRE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Danio rerio 15378 R-DRE-70940 https://reactome.org/PathwayBrowser/#/R-DRE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Danio rerio 15378 R-DRE-70941 https://reactome.org/PathwayBrowser/#/R-DRE-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Danio rerio 15378 R-DRE-70975 https://reactome.org/PathwayBrowser/#/R-DRE-70975 CS acetylates OA to citrate IEA Danio rerio 15378 R-DRE-70979 https://reactome.org/PathwayBrowser/#/R-DRE-70979 MDH2 dimer dehydrogenates MAL IEA Danio rerio 15378 R-DRE-71130 https://reactome.org/PathwayBrowser/#/R-DRE-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Danio rerio 15378 R-DRE-71164 https://reactome.org/PathwayBrowser/#/R-DRE-71164 HGD dioxygenates homogentisate IEA Danio rerio 15378 R-DRE-71200 https://reactome.org/PathwayBrowser/#/R-DRE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Danio rerio 15378 R-DRE-71260 https://reactome.org/PathwayBrowser/#/R-DRE-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Danio rerio 15378 R-DRE-71286 https://reactome.org/PathwayBrowser/#/R-DRE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Danio rerio 15378 R-DRE-71299 https://reactome.org/PathwayBrowser/#/R-DRE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Danio rerio 15378 R-DRE-71401 https://reactome.org/PathwayBrowser/#/R-DRE-71401 OGDH dimer decarboxylates 2-OG IEA Danio rerio 15378 R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 15378 R-DRE-71707 https://reactome.org/PathwayBrowser/#/R-DRE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Danio rerio 15378 R-DRE-71723 https://reactome.org/PathwayBrowser/#/R-DRE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Danio rerio 15378 R-DRE-71849 https://reactome.org/PathwayBrowser/#/R-DRE-71849 LDH tetramer reduces PYR to LACT IEA Danio rerio 15378 R-DRE-73585 https://reactome.org/PathwayBrowser/#/R-DRE-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Danio rerio 15378 R-DRE-73589 https://reactome.org/PathwayBrowser/#/R-DRE-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Danio rerio 15378 R-DRE-73591 https://reactome.org/PathwayBrowser/#/R-DRE-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Danio rerio 15378 R-DRE-73596 https://reactome.org/PathwayBrowser/#/R-DRE-73596 dCMP + H2O => dUMP + NH4+ IEA Danio rerio 15378 R-DRE-73616 https://reactome.org/PathwayBrowser/#/R-DRE-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Danio rerio 15378 R-DRE-73618 https://reactome.org/PathwayBrowser/#/R-DRE-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Danio rerio 15378 R-DRE-73620 https://reactome.org/PathwayBrowser/#/R-DRE-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Danio rerio 15378 R-DRE-73647 https://reactome.org/PathwayBrowser/#/R-DRE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Danio rerio 15378 R-DRE-73666 https://reactome.org/PathwayBrowser/#/R-DRE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Danio rerio 15378 R-DRE-73794 https://reactome.org/PathwayBrowser/#/R-DRE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Danio rerio 15378 R-DRE-73805 https://reactome.org/PathwayBrowser/#/R-DRE-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Danio rerio 15378 R-DRE-73806 https://reactome.org/PathwayBrowser/#/R-DRE-73806 AIR + CO2 => CAIR IEA Danio rerio 15378 R-DRE-73810 https://reactome.org/PathwayBrowser/#/R-DRE-73810 FGAM + ATP => AIR + ADP + Pi IEA Danio rerio 15378 R-DRE-73813 https://reactome.org/PathwayBrowser/#/R-DRE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Danio rerio 15378 R-DRE-73814 https://reactome.org/PathwayBrowser/#/R-DRE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Danio rerio 15378 R-DRE-73912 https://reactome.org/PathwayBrowser/#/R-DRE-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Danio rerio 15378 R-DRE-73920 https://reactome.org/PathwayBrowser/#/R-DRE-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Danio rerio 15378 R-DRE-74255 https://reactome.org/PathwayBrowser/#/R-DRE-74255 Guanine + H2O => Xanthine + NH4+ IEA Danio rerio 15378 R-DRE-74723 https://reactome.org/PathwayBrowser/#/R-DRE-74723 Endosome acidification IEA Danio rerio 15378 R-DRE-74872 https://reactome.org/PathwayBrowser/#/R-DRE-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Danio rerio 15378 R-DRE-75872 https://reactome.org/PathwayBrowser/#/R-DRE-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Danio rerio 15378 R-DRE-75883 https://reactome.org/PathwayBrowser/#/R-DRE-75883 DHRS7B reduces GO3P to HXDG3P IEA Danio rerio 15378 R-DRE-75889 https://reactome.org/PathwayBrowser/#/R-DRE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Danio rerio 15378 R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 15378 R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 15378 R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 15378 R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 15378 R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 15378 R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 15378 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 15378 R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 15378 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 15378 R-DRE-77254 https://reactome.org/PathwayBrowser/#/R-DRE-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Danio rerio 15378 R-DRE-77283 https://reactome.org/PathwayBrowser/#/R-DRE-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Danio rerio 15378 R-DRE-77303 https://reactome.org/PathwayBrowser/#/R-DRE-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Danio rerio 15378 R-DRE-77312 https://reactome.org/PathwayBrowser/#/R-DRE-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Danio rerio 15378 R-DRE-77323 https://reactome.org/PathwayBrowser/#/R-DRE-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Danio rerio 15378 R-DRE-77331 https://reactome.org/PathwayBrowser/#/R-DRE-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Danio rerio 15378 R-DRE-77342 https://reactome.org/PathwayBrowser/#/R-DRE-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Danio rerio 15378 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 15378 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 15378 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 15378 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 15378 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 15378 R-DRE-8862152 https://reactome.org/PathwayBrowser/#/R-DRE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Danio rerio 15378 R-DRE-8863494 https://reactome.org/PathwayBrowser/#/R-DRE-8863494 ASICs bind STOML3, (STOM) IEA Danio rerio 15378 R-DRE-8866601 https://reactome.org/PathwayBrowser/#/R-DRE-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Danio rerio 15378 R-DRE-8869607 https://reactome.org/PathwayBrowser/#/R-DRE-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Danio rerio 15378 R-DRE-8869627 https://reactome.org/PathwayBrowser/#/R-DRE-8869627 NMRK2 phosphorylates NR to yield NMN IEA Danio rerio 15378 R-DRE-8875623 https://reactome.org/PathwayBrowser/#/R-DRE-8875623 SLC25A18,22 import L-Glu, H+ IEA Danio rerio 15378 R-DRE-888572 https://reactome.org/PathwayBrowser/#/R-DRE-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Danio rerio 15378 R-DRE-8936442 https://reactome.org/PathwayBrowser/#/R-DRE-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Danio rerio 15378 R-DRE-8952873 https://reactome.org/PathwayBrowser/#/R-DRE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Danio rerio 15378 R-DRE-8954468 https://reactome.org/PathwayBrowser/#/R-DRE-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Danio rerio 15378 R-DRE-8955760 https://reactome.org/PathwayBrowser/#/R-DRE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Danio rerio 15378 R-DRE-8956458 https://reactome.org/PathwayBrowser/#/R-DRE-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Danio rerio 15378 R-DRE-8959510 https://reactome.org/PathwayBrowser/#/R-DRE-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Danio rerio 15378 R-DRE-9011595 https://reactome.org/PathwayBrowser/#/R-DRE-9011595 GSTZ1 dimer dehalogenates DCA IEA Danio rerio 15378 R-DRE-9012016 https://reactome.org/PathwayBrowser/#/R-DRE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Danio rerio 15378 R-DRE-9012036 https://reactome.org/PathwayBrowser/#/R-DRE-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Danio rerio 15378 R-DRE-9024993 https://reactome.org/PathwayBrowser/#/R-DRE-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Danio rerio 15378 R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio 15378 R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 15378 R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 15378 R-DRE-9037761 https://reactome.org/PathwayBrowser/#/R-DRE-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Danio rerio 15378 R-DRE-917841 https://reactome.org/PathwayBrowser/#/R-DRE-917841 Acidification of Tf:TfR1 containing endosome IEA Danio rerio 15378 R-DRE-917891 https://reactome.org/PathwayBrowser/#/R-DRE-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Danio rerio 15378 R-DRE-9620103 https://reactome.org/PathwayBrowser/#/R-DRE-9620103 ALDH2 transforms GTN to NO IEA Danio rerio 15378 R-DRE-9650165 https://reactome.org/PathwayBrowser/#/R-DRE-9650165 ASIC trimers bind H+ IEA Danio rerio 15378 R-DRE-9705713 https://reactome.org/PathwayBrowser/#/R-DRE-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Danio rerio 15378 R-DRE-9705714 https://reactome.org/PathwayBrowser/#/R-DRE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Danio rerio 15378 R-DRE-9709098 https://reactome.org/PathwayBrowser/#/R-DRE-9709098 DHFR dimer reduces FOLA to DHF IEA Danio rerio 15378 R-DRE-9731228 https://reactome.org/PathwayBrowser/#/R-DRE-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Danio rerio 15378 R-DRE-9731590 https://reactome.org/PathwayBrowser/#/R-DRE-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Danio rerio 15378 R-DRE-9731613 https://reactome.org/PathwayBrowser/#/R-DRE-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Danio rerio 15378 R-DRE-9731632 https://reactome.org/PathwayBrowser/#/R-DRE-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Danio rerio 15378 R-DRE-9731661 https://reactome.org/PathwayBrowser/#/R-DRE-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Danio rerio 15378 R-DRE-9748945 https://reactome.org/PathwayBrowser/#/R-DRE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Danio rerio 15378 R-DRE-9748979 https://reactome.org/PathwayBrowser/#/R-DRE-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Danio rerio 15378 R-DRE-9748983 https://reactome.org/PathwayBrowser/#/R-DRE-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Danio rerio 15378 R-DRE-9749647 https://reactome.org/PathwayBrowser/#/R-DRE-9749647 CES2 hydrolyzes ASA- IEA Danio rerio 15378 R-DRE-9749792 https://reactome.org/PathwayBrowser/#/R-DRE-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Danio rerio 15378 R-DRE-9753285 https://reactome.org/PathwayBrowser/#/R-DRE-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Danio rerio 15378 R-DRE-9755937 https://reactome.org/PathwayBrowser/#/R-DRE-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Danio rerio 15378 R-DRE-9756138 https://reactome.org/PathwayBrowser/#/R-DRE-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Danio rerio 15378 R-DRE-9756162 https://reactome.org/PathwayBrowser/#/R-DRE-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Danio rerio 15378 R-DRE-9756169 https://reactome.org/PathwayBrowser/#/R-DRE-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Danio rerio 15378 R-DRE-9756177 https://reactome.org/PathwayBrowser/#/R-DRE-9756177 PON1,3 hydrolyse ATVL to ATV IEA Danio rerio 15378 R-DRE-9756180 https://reactome.org/PathwayBrowser/#/R-DRE-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Danio rerio 15378 R-DRE-975629 https://reactome.org/PathwayBrowser/#/R-DRE-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Danio rerio 15378 R-DRE-9757706 https://reactome.org/PathwayBrowser/#/R-DRE-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Danio rerio 15378 R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 15378 R-DRE-9758674 https://reactome.org/PathwayBrowser/#/R-DRE-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Danio rerio 15378 R-DRE-9759259 https://reactome.org/PathwayBrowser/#/R-DRE-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Danio rerio 15378 R-DRE-9759549 https://reactome.org/PathwayBrowser/#/R-DRE-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Danio rerio 15378 R-DRE-9794270 https://reactome.org/PathwayBrowser/#/R-DRE-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Danio rerio 15378 R-DRE-9837337 https://reactome.org/PathwayBrowser/#/R-DRE-9837337 DCAKD phosphorylates DP-CoA IEA Danio rerio 15378 R-DRE-9844587 https://reactome.org/PathwayBrowser/#/R-DRE-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Danio rerio 15378 R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 15378 R-DRE-9846501 https://reactome.org/PathwayBrowser/#/R-DRE-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Danio rerio 15378 R-DRE-9851347 https://reactome.org/PathwayBrowser/#/R-DRE-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Danio rerio 15378 R-DRE-9853499 https://reactome.org/PathwayBrowser/#/R-DRE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Danio rerio 15378 R-DRE-9854315 https://reactome.org/PathwayBrowser/#/R-DRE-9854315 CSKMT methylates Citrate Synthase IEA Danio rerio 15378 R-DRE-9854415 https://reactome.org/PathwayBrowser/#/R-DRE-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Danio rerio 15378 R-DRE-9856871 https://reactome.org/PathwayBrowser/#/R-DRE-9856871 MDH1 reduces OA IEA Danio rerio 15378 R-DRE-9861660 https://reactome.org/PathwayBrowser/#/R-DRE-9861660 ME1 tetramer decarboxylates OA to PYR IEA Danio rerio 15378 R-ECO-1222667 https://reactome.org/PathwayBrowser/#/R-ECO-1222667 Iron is reduced and separates from enterobactin TAS Escherichia coli 15378 R-FCA-164926 https://reactome.org/PathwayBrowser/#/R-FCA-164926 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ TAS Felis catus 15378 R-GGA-109343 https://reactome.org/PathwayBrowser/#/R-GGA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Gallus gallus 15378 R-GGA-111524 https://reactome.org/PathwayBrowser/#/R-GGA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Gallus gallus 15378 R-GGA-1222376 https://reactome.org/PathwayBrowser/#/R-GGA-1222376 NOX2 generates superoxide from oxygen IEA Gallus gallus 15378 R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus 15378 R-GGA-1236967 https://reactome.org/PathwayBrowser/#/R-GGA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Gallus gallus 15378 R-GGA-1237045 https://reactome.org/PathwayBrowser/#/R-GGA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Gallus gallus 15378 R-GGA-1237047 https://reactome.org/PathwayBrowser/#/R-GGA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Gallus gallus 15378 R-GGA-1237059 https://reactome.org/PathwayBrowser/#/R-GGA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Gallus gallus 15378 R-GGA-1237081 https://reactome.org/PathwayBrowser/#/R-GGA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Gallus gallus 15378 R-GGA-1237129 https://reactome.org/PathwayBrowser/#/R-GGA-1237129 Acireductone is created IEA Gallus gallus 15378 R-GGA-1237325 https://reactome.org/PathwayBrowser/#/R-GGA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Gallus gallus 15378 R-GGA-1247668 https://reactome.org/PathwayBrowser/#/R-GGA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Gallus gallus 15378 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 15378 R-GGA-140359 https://reactome.org/PathwayBrowser/#/R-GGA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Gallus gallus 15378 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 15378 R-GGA-1475017 https://reactome.org/PathwayBrowser/#/R-GGA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Gallus gallus 15378 R-GGA-1475022 https://reactome.org/PathwayBrowser/#/R-GGA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Gallus gallus 15378 R-GGA-1475025 https://reactome.org/PathwayBrowser/#/R-GGA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Gallus gallus 15378 R-GGA-1475026 https://reactome.org/PathwayBrowser/#/R-GGA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Gallus gallus 15378 R-GGA-1475028 https://reactome.org/PathwayBrowser/#/R-GGA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Gallus gallus 15378 R-GGA-1475032 https://reactome.org/PathwayBrowser/#/R-GGA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Gallus gallus 15378 R-GGA-1475435 https://reactome.org/PathwayBrowser/#/R-GGA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Gallus gallus 15378 R-GGA-1475436 https://reactome.org/PathwayBrowser/#/R-GGA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Gallus gallus 15378 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 15378 R-GGA-1497869 https://reactome.org/PathwayBrowser/#/R-GGA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Gallus gallus 15378 R-GGA-1562626 https://reactome.org/PathwayBrowser/#/R-GGA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Gallus gallus 15378 R-GGA-156526 https://reactome.org/PathwayBrowser/#/R-GGA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Gallus gallus 15378 R-GGA-158609 https://reactome.org/PathwayBrowser/#/R-GGA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Gallus gallus 15378 R-GGA-1605797 https://reactome.org/PathwayBrowser/#/R-GGA-1605797 SMPD1 hydrolyzes SPHM IEA Gallus gallus 15378 R-GGA-1606273 https://reactome.org/PathwayBrowser/#/R-GGA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Gallus gallus 15378 R-GGA-1606288 https://reactome.org/PathwayBrowser/#/R-GGA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Gallus gallus 15378 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 15378 R-GGA-1614362 https://reactome.org/PathwayBrowser/#/R-GGA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Gallus gallus 15378 R-GGA-162730 https://reactome.org/PathwayBrowser/#/R-GGA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Gallus gallus 15378 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 15378 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Gallus gallus 15378 R-GGA-1638104 https://reactome.org/PathwayBrowser/#/R-GGA-1638104 UGCG transfers glucose to ceramide IEA Gallus gallus 15378 R-GGA-1638845 https://reactome.org/PathwayBrowser/#/R-GGA-1638845 CERK phosphorylates CERA to form C1P IEA Gallus gallus 15378 R-GGA-1640164 https://reactome.org/PathwayBrowser/#/R-GGA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Gallus gallus 15378 R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus 15378 R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus 15378 R-GGA-170026 https://reactome.org/PathwayBrowser/#/R-GGA-170026 Protons are translocated from the intermembrane space to the matrix IEA Gallus gallus 15378 R-GGA-173597 https://reactome.org/PathwayBrowser/#/R-GGA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Gallus gallus 15378 R-GGA-174389 https://reactome.org/PathwayBrowser/#/R-GGA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Gallus gallus 15378 R-GGA-174392 https://reactome.org/PathwayBrowser/#/R-GGA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Gallus gallus 15378 R-GGA-189421 https://reactome.org/PathwayBrowser/#/R-GGA-189421 CPO transforms COPRO3 to PPGEN9 IEA Gallus gallus 15378 R-GGA-189425 https://reactome.org/PathwayBrowser/#/R-GGA-189425 UROD decarboxylates URO3 to COPRO3 IEA Gallus gallus 15378 R-GGA-189439 https://reactome.org/PathwayBrowser/#/R-GGA-189439 ALAD condenses 2 dALAs to form PBG IEA Gallus gallus 15378 R-GGA-189442 https://reactome.org/PathwayBrowser/#/R-GGA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Gallus gallus 15378 R-GGA-189465 https://reactome.org/PathwayBrowser/#/R-GGA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Gallus gallus 15378 R-GGA-190182 https://reactome.org/PathwayBrowser/#/R-GGA-190182 UROD decarboxylates URO1 to COPRO1 IEA Gallus gallus 15378 R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 15378 R-GGA-191323 https://reactome.org/PathwayBrowser/#/R-GGA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Gallus gallus 15378 R-GGA-191352 https://reactome.org/PathwayBrowser/#/R-GGA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Gallus gallus 15378 R-GGA-191402 https://reactome.org/PathwayBrowser/#/R-GGA-191402 Reduction of presqualene diphosphate to form squalene IEA Gallus gallus 15378 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 15378 R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 15378 R-GGA-192033 https://reactome.org/PathwayBrowser/#/R-GGA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Gallus gallus 15378 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 15378 R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 15378 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 15378 R-GGA-192067 https://reactome.org/PathwayBrowser/#/R-GGA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Gallus gallus 15378 R-GGA-192178 https://reactome.org/PathwayBrowser/#/R-GGA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Gallus gallus 15378 R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 15378 R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 15378 R-GGA-193064 https://reactome.org/PathwayBrowser/#/R-GGA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Gallus gallus 15378 R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 15378 R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 15378 R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 15378 R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 15378 R-GGA-193073 https://reactome.org/PathwayBrowser/#/R-GGA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Gallus gallus 15378 R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 15378 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 15378 R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 15378 R-GGA-193455 https://reactome.org/PathwayBrowser/#/R-GGA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 15378 R-GGA-193508 https://reactome.org/PathwayBrowser/#/R-GGA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 15378 R-GGA-193746 https://reactome.org/PathwayBrowser/#/R-GGA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Gallus gallus 15378 R-GGA-193755 https://reactome.org/PathwayBrowser/#/R-GGA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Gallus gallus 15378 R-GGA-193821 https://reactome.org/PathwayBrowser/#/R-GGA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Gallus gallus 15378 R-GGA-193824 https://reactome.org/PathwayBrowser/#/R-GGA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Gallus gallus 15378 R-GGA-193964 https://reactome.org/PathwayBrowser/#/R-GGA-193964 CYP21A2 21-hydroxylates PROG IEA Gallus gallus 15378 R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 15378 R-GGA-194023 https://reactome.org/PathwayBrowser/#/R-GGA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Gallus gallus 15378 R-GGA-194632 https://reactome.org/PathwayBrowser/#/R-GGA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Gallus gallus 15378 R-GGA-194641 https://reactome.org/PathwayBrowser/#/R-GGA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15378 R-GGA-194642 https://reactome.org/PathwayBrowser/#/R-GGA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Gallus gallus 15378 R-GGA-194669 https://reactome.org/PathwayBrowser/#/R-GGA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15378 R-GGA-194674 https://reactome.org/PathwayBrowser/#/R-GGA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Gallus gallus 15378 R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 15378 R-GGA-194689 https://reactome.org/PathwayBrowser/#/R-GGA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15378 R-GGA-194718 https://reactome.org/PathwayBrowser/#/R-GGA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Gallus gallus 15378 R-GGA-195664 https://reactome.org/PathwayBrowser/#/R-GGA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Gallus gallus 15378 R-GGA-196060 https://reactome.org/PathwayBrowser/#/R-GGA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Gallus gallus 15378 R-GGA-196350 https://reactome.org/PathwayBrowser/#/R-GGA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Gallus gallus 15378 R-GGA-196372 https://reactome.org/PathwayBrowser/#/R-GGA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Gallus gallus 15378 R-GGA-196402 https://reactome.org/PathwayBrowser/#/R-GGA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Gallus gallus 15378 R-GGA-196417 https://reactome.org/PathwayBrowser/#/R-GGA-196417 Reduction of desmosterol to cholesterol IEA Gallus gallus 15378 R-GGA-196753 https://reactome.org/PathwayBrowser/#/R-GGA-196753 2xPPCS ligates PPanK with Cys IEA Gallus gallus 15378 R-GGA-196754 https://reactome.org/PathwayBrowser/#/R-GGA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Gallus gallus 15378 R-GGA-196773 https://reactome.org/PathwayBrowser/#/R-GGA-196773 COASY phosphorylates DP-CoA IEA Gallus gallus 15378 R-GGA-196840 https://reactome.org/PathwayBrowser/#/R-GGA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Gallus gallus 15378 R-GGA-196857 https://reactome.org/PathwayBrowser/#/R-GGA-196857 PANK2 phosphorylates PanK IEA Gallus gallus 15378 R-GGA-196929 https://reactome.org/PathwayBrowser/#/R-GGA-196929 FLAD1 phosphorylates FMN IEA Gallus gallus 15378 R-GGA-196964 https://reactome.org/PathwayBrowser/#/R-GGA-196964 RFK:Mg2+ phosphorylates RIB IEA Gallus gallus 15378 R-GGA-197186 https://reactome.org/PathwayBrowser/#/R-GGA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Gallus gallus 15378 R-GGA-197268 https://reactome.org/PathwayBrowser/#/R-GGA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Gallus gallus 15378 R-GGA-197963 https://reactome.org/PathwayBrowser/#/R-GGA-197963 DHFR2 reduces FOLA to DHF IEA Gallus gallus 15378 R-GGA-197972 https://reactome.org/PathwayBrowser/#/R-GGA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Gallus gallus 15378 R-GGA-198824 https://reactome.org/PathwayBrowser/#/R-GGA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Gallus gallus 15378 R-GGA-199203 https://reactome.org/PathwayBrowser/#/R-GGA-199203 PANK1/3 phosphorylate PanK IEA Gallus gallus 15378 R-GGA-200644 https://reactome.org/PathwayBrowser/#/R-GGA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Gallus gallus 15378 R-GGA-200676 https://reactome.org/PathwayBrowser/#/R-GGA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Gallus gallus 15378 R-GGA-200718 https://reactome.org/PathwayBrowser/#/R-GGA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Gallus gallus 15378 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 15378 R-GGA-204662 https://reactome.org/PathwayBrowser/#/R-GGA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Gallus gallus 15378 R-GGA-209772 https://reactome.org/PathwayBrowser/#/R-GGA-209772 Thyroxine is deiodinated to triiodothyronine IEA Gallus gallus 15378 R-GGA-209821 https://reactome.org/PathwayBrowser/#/R-GGA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Gallus gallus 15378 R-GGA-209845 https://reactome.org/PathwayBrowser/#/R-GGA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Gallus gallus 15378 R-GGA-209903 https://reactome.org/PathwayBrowser/#/R-GGA-209903 Noradrenaline is converted to adrenaline IEA Gallus gallus 15378 R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 15378 R-GGA-210404 https://reactome.org/PathwayBrowser/#/R-GGA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Gallus gallus 15378 R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 15378 R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 15378 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 15378 R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus 15378 R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 15378 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 15378 R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 15378 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 15378 R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 15378 R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 15378 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 15378 R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 15378 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 15378 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 15378 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 15378 R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 15378 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 15378 R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 15378 R-GGA-2161187 https://reactome.org/PathwayBrowser/#/R-GGA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Gallus gallus 15378 R-GGA-2161651 https://reactome.org/PathwayBrowser/#/R-GGA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Gallus gallus 15378 R-GGA-2161779 https://reactome.org/PathwayBrowser/#/R-GGA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Gallus gallus 15378 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Gallus gallus 15378 R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 15378 R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus 15378 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Gallus gallus 15378 R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 15378 R-GGA-2161951 https://reactome.org/PathwayBrowser/#/R-GGA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Gallus gallus 15378 R-GGA-2162078 https://reactome.org/PathwayBrowser/#/R-GGA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Gallus gallus 15378 R-GGA-2162186 https://reactome.org/PathwayBrowser/#/R-GGA-2162186 COQ3 methylates DeMQ10H2 IEA Gallus gallus 15378 R-GGA-2162188 https://reactome.org/PathwayBrowser/#/R-GGA-2162188 COQ5 methylates MDMQ10H2 IEA Gallus gallus 15378 R-GGA-2162193 https://reactome.org/PathwayBrowser/#/R-GGA-2162193 COQ3 methylates DHDB IEA Gallus gallus 15378 R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 15378 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 15378 R-GGA-2395512 https://reactome.org/PathwayBrowser/#/R-GGA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Gallus gallus 15378 R-GGA-2395517 https://reactome.org/PathwayBrowser/#/R-GGA-2395517 NADPH transfers electrons to FDXR IEA Gallus gallus 15378 R-GGA-2395818 https://reactome.org/PathwayBrowser/#/R-GGA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Gallus gallus 15378 R-GGA-2395849 https://reactome.org/PathwayBrowser/#/R-GGA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 15378 R-GGA-2395869 https://reactome.org/PathwayBrowser/#/R-GGA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 15378 R-GGA-2395872 https://reactome.org/PathwayBrowser/#/R-GGA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Gallus gallus 15378 R-GGA-2395876 https://reactome.org/PathwayBrowser/#/R-GGA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Gallus gallus 15378 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 15378 R-GGA-2454081 https://reactome.org/PathwayBrowser/#/R-GGA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Gallus gallus 15378 R-GGA-2464822 https://reactome.org/PathwayBrowser/#/R-GGA-2464822 RDH12 reduces atRAL to atROL IEA Gallus gallus 15378 R-GGA-2465940 https://reactome.org/PathwayBrowser/#/R-GGA-2465940 atRAL is reduced to atROL IEA Gallus gallus 15378 R-GGA-2465974 https://reactome.org/PathwayBrowser/#/R-GGA-2465974 An REH hydrolyses 11cRE to 11cROL TAS Gallus gallus 15378 R-GGA-2509827 https://reactome.org/PathwayBrowser/#/R-GGA-2509827 ITPA hydrolyses ITP to IMP IEA Gallus gallus 15378 R-GGA-2509831 https://reactome.org/PathwayBrowser/#/R-GGA-2509831 ITPA hydrolyses XTP to XMP IEA Gallus gallus 15378 R-GGA-2509838 https://reactome.org/PathwayBrowser/#/R-GGA-2509838 ITPA hydrolyses dITP to dIMP IEA Gallus gallus 15378 R-GGA-2534378 https://reactome.org/PathwayBrowser/#/R-GGA-2534378 Hv1 Mediated H+ Permeability IEA Gallus gallus 15378 R-GGA-264615 https://reactome.org/PathwayBrowser/#/R-GGA-264615 Loading of acetylcholine in synaptic vesicles IEA Gallus gallus 15378 R-GGA-2671885 https://reactome.org/PathwayBrowser/#/R-GGA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Gallus gallus 15378 R-GGA-2730692 https://reactome.org/PathwayBrowser/#/R-GGA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Gallus gallus 15378 R-GGA-2730959 https://reactome.org/PathwayBrowser/#/R-GGA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Gallus gallus 15378 R-GGA-2855252 https://reactome.org/PathwayBrowser/#/R-GGA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Gallus gallus 15378 R-GGA-2872444 https://reactome.org/PathwayBrowser/#/R-GGA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Gallus gallus 15378 R-GGA-2889070 https://reactome.org/PathwayBrowser/#/R-GGA-2889070 SLC9B2 exchanges Na+ for H+ IEA Gallus gallus 15378 R-GGA-3095889 https://reactome.org/PathwayBrowser/#/R-GGA-3095889 MMACHC dealkylates RCbl IEA Gallus gallus 15378 R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus 15378 R-GGA-3149519 https://reactome.org/PathwayBrowser/#/R-GGA-3149519 MMACHC decyanates CNCbl IEA Gallus gallus 15378 R-GGA-3159253 https://reactome.org/PathwayBrowser/#/R-GGA-3159253 MMAB adenosylates cob(I)alamin IEA Gallus gallus 15378 R-GGA-3299680 https://reactome.org/PathwayBrowser/#/R-GGA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Gallus gallus 15378 R-GGA-3299682 https://reactome.org/PathwayBrowser/#/R-GGA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Gallus gallus 15378 R-GGA-3299691 https://reactome.org/PathwayBrowser/#/R-GGA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Gallus gallus 15378 R-GGA-3323050 https://reactome.org/PathwayBrowser/#/R-GGA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Gallus gallus 15378 R-GGA-3323079 https://reactome.org/PathwayBrowser/#/R-GGA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 15378 R-GGA-350901 https://reactome.org/PathwayBrowser/#/R-GGA-350901 Iodide is organified IEA Gallus gallus 15378 R-GGA-352174 https://reactome.org/PathwayBrowser/#/R-GGA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Gallus gallus 15378 R-GGA-352921 https://reactome.org/PathwayBrowser/#/R-GGA-352921 1,3-bisphosphoglycerate + NADH + H+ <=> glyceraldehyde 3-phosphate + NAD+ + phosphate TAS Gallus gallus 15378 R-GGA-352956 https://reactome.org/PathwayBrowser/#/R-GGA-352956 glyceraldehyde 3-phosphate + NAD+ + phosphate <=> 1,3-bisphosphoglycerate + NADH + H+ TAS Gallus gallus 15378 R-GGA-372359 https://reactome.org/PathwayBrowser/#/R-GGA-372359 pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] IEA Gallus gallus 15378 R-GGA-372422 https://reactome.org/PathwayBrowser/#/R-GGA-372422 oxaloacetate + NADH + H+ <=> malate + NAD+ TAS Gallus gallus 15378 R-GGA-372448 https://reactome.org/PathwayBrowser/#/R-GGA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Gallus gallus 15378 R-GGA-372855 https://reactome.org/PathwayBrowser/#/R-GGA-372855 malate + NAD+ <=> oxaloacetate + NADH + H+ TAS Gallus gallus 15378 R-GGA-372903 https://reactome.org/PathwayBrowser/#/R-GGA-372903 lactate + NAD+ <=> pyruvate + NADH + H+ TAS Gallus gallus 15378 R-GGA-372910 https://reactome.org/PathwayBrowser/#/R-GGA-372910 pyruvate + NADH + H+ <=> lactate + NAD+ TAS Gallus gallus 15378 R-GGA-373024 https://reactome.org/PathwayBrowser/#/R-GGA-373024 isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ IEA Gallus gallus 15378 R-GGA-373042 https://reactome.org/PathwayBrowser/#/R-GGA-373042 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ IEA Gallus gallus 15378 R-GGA-373047 https://reactome.org/PathwayBrowser/#/R-GGA-373047 malate + NAD+ <=> oxaloacetate + NADH + H+ IEA Gallus gallus 15378 R-GGA-373177 https://reactome.org/PathwayBrowser/#/R-GGA-373177 pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ TAS Gallus gallus 15378 R-GGA-373867 https://reactome.org/PathwayBrowser/#/R-GGA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-GGA-373875 https://reactome.org/PathwayBrowser/#/R-GGA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Gallus gallus 15378 R-GGA-373887 https://reactome.org/PathwayBrowser/#/R-GGA-373887 lactate + H+ [extracellular] <=> lactate + H+ [cytosol] IEA Gallus gallus 15378 R-GGA-373889 https://reactome.org/PathwayBrowser/#/R-GGA-373889 lactate + H+ [cytosol] <=> lactate + H+ [extracellular] IEA Gallus gallus 15378 R-GGA-375405 https://reactome.org/PathwayBrowser/#/R-GGA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-GGA-375417 https://reactome.org/PathwayBrowser/#/R-GGA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Gallus gallus 15378 R-GGA-3777112 https://reactome.org/PathwayBrowser/#/R-GGA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Gallus gallus 15378 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 15378 R-GGA-380608 https://reactome.org/PathwayBrowser/#/R-GGA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Gallus gallus 15378 R-GGA-389540 https://reactome.org/PathwayBrowser/#/R-GGA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 15378 R-GGA-389550 https://reactome.org/PathwayBrowser/#/R-GGA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 15378 R-GGA-389609 https://reactome.org/PathwayBrowser/#/R-GGA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Gallus gallus 15378 R-GGA-389826 https://reactome.org/PathwayBrowser/#/R-GGA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Gallus gallus 15378 R-GGA-389995 https://reactome.org/PathwayBrowser/#/R-GGA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Gallus gallus 15378 R-GGA-390251 https://reactome.org/PathwayBrowser/#/R-GGA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 15378 R-GGA-390425 https://reactome.org/PathwayBrowser/#/R-GGA-390425 FAR1 reduces PalmCoA to HXOL IEA Gallus gallus 15378 R-GGA-390438 https://reactome.org/PathwayBrowser/#/R-GGA-390438 FAR2 reduces PalmCoA to HXOL IEA Gallus gallus 15378 R-GGA-418365 https://reactome.org/PathwayBrowser/#/R-GGA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Gallus gallus 15378 R-GGA-419465 https://reactome.org/PathwayBrowser/#/R-GGA-419465 N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O IEA Gallus gallus 15378 R-GGA-421158 https://reactome.org/PathwayBrowser/#/R-GGA-421158 xanthine + H2O + NAD+ => urate + NADH + H+ TAS Gallus gallus 15378 R-GGA-421161 https://reactome.org/PathwayBrowser/#/R-GGA-421161 hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ TAS Gallus gallus 15378 R-GGA-421222 https://reactome.org/PathwayBrowser/#/R-GGA-421222 inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ IEA Gallus gallus 15378 R-GGA-421447 https://reactome.org/PathwayBrowser/#/R-GGA-421447 protoporphyrin IX + Fe++ => heme + 2 H+ TAS Gallus gallus 15378 R-GGA-425577 https://reactome.org/PathwayBrowser/#/R-GGA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Gallus gallus 15378 R-GGA-425965 https://reactome.org/PathwayBrowser/#/R-GGA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Gallus gallus 15378 R-GGA-425983 https://reactome.org/PathwayBrowser/#/R-GGA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Gallus gallus 15378 R-GGA-425994 https://reactome.org/PathwayBrowser/#/R-GGA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Gallus gallus 15378 R-GGA-426015 https://reactome.org/PathwayBrowser/#/R-GGA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Gallus gallus 15378 R-GGA-426043 https://reactome.org/PathwayBrowser/#/R-GGA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Gallus gallus 15378 R-GGA-427555 https://reactome.org/PathwayBrowser/#/R-GGA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-GGA-427910 https://reactome.org/PathwayBrowser/#/R-GGA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Gallus gallus 15378 R-GGA-427998 https://reactome.org/PathwayBrowser/#/R-GGA-427998 Proton-coupled di- and tri-peptide cotransport IEA Gallus gallus 15378 R-GGA-428007 https://reactome.org/PathwayBrowser/#/R-GGA-428007 Proton-coupled histidine and di-peptide cotransport IEA Gallus gallus 15378 R-GGA-428015 https://reactome.org/PathwayBrowser/#/R-GGA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Gallus gallus 15378 R-GGA-428052 https://reactome.org/PathwayBrowser/#/R-GGA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Gallus gallus 15378 R-GGA-428127 https://reactome.org/PathwayBrowser/#/R-GGA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Gallus gallus 15378 R-GGA-428185 https://reactome.org/PathwayBrowser/#/R-GGA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Gallus gallus 15378 R-GGA-428259 https://reactome.org/PathwayBrowser/#/R-GGA-428259 DEGS1 dehydrogenates dihydroceramide IEA Gallus gallus 15378 R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 15378 R-GGA-428273 https://reactome.org/PathwayBrowser/#/R-GGA-428273 SPHK1 phosphorylates sphingoid IEA Gallus gallus 15378 R-GGA-428585 https://reactome.org/PathwayBrowser/#/R-GGA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Gallus gallus 15378 R-GGA-428625 https://reactome.org/PathwayBrowser/#/R-GGA-428625 Vesicular inhibitory amino acid transport IEA Gallus gallus 15378 R-GGA-429101 https://reactome.org/PathwayBrowser/#/R-GGA-429101 HMIT co-transports myo-inositol with a proton IEA Gallus gallus 15378 R-GGA-429157 https://reactome.org/PathwayBrowser/#/R-GGA-429157 ABCC4 accumulation of dense granule contents IEA Gallus gallus 15378 R-GGA-433576 https://reactome.org/PathwayBrowser/#/R-GGA-433576 3-dehydrosphinganine + NADPH + H+ => sphinganine + NADP+ IEA Gallus gallus 15378 R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 15378 R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 15378 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-GGA-434650 https://reactome.org/PathwayBrowser/#/R-GGA-434650 MATEs mediate extrusion of xenobiotics IEA Gallus gallus 15378 R-GGA-435171 https://reactome.org/PathwayBrowser/#/R-GGA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Gallus gallus 15378 R-GGA-435349 https://reactome.org/PathwayBrowser/#/R-GGA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-GGA-444393 https://reactome.org/PathwayBrowser/#/R-GGA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Gallus gallus 15378 R-GGA-444419 https://reactome.org/PathwayBrowser/#/R-GGA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Gallus gallus 15378 R-GGA-444731 https://reactome.org/PathwayBrowser/#/R-GGA-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Gallus gallus 15378 R-GGA-446277 https://reactome.org/PathwayBrowser/#/R-GGA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Gallus gallus 15378 R-GGA-446278 https://reactome.org/PathwayBrowser/#/R-GGA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Gallus gallus 15378 R-GGA-450971 https://reactome.org/PathwayBrowser/#/R-GGA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Gallus gallus 15378 R-GGA-469659 https://reactome.org/PathwayBrowser/#/R-GGA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Gallus gallus 15378 R-GGA-504054 https://reactome.org/PathwayBrowser/#/R-GGA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Gallus gallus 15378 R-GGA-508040 https://reactome.org/PathwayBrowser/#/R-GGA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Gallus gallus 15378 R-GGA-508369 https://reactome.org/PathwayBrowser/#/R-GGA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Gallus gallus 15378 R-GGA-508473 https://reactome.org/PathwayBrowser/#/R-GGA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Gallus gallus 15378 R-GGA-514604 https://reactome.org/PathwayBrowser/#/R-GGA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Gallus gallus 15378 R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus 15378 R-GGA-5263614 https://reactome.org/PathwayBrowser/#/R-GGA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Gallus gallus 15378 R-GGA-5263616 https://reactome.org/PathwayBrowser/#/R-GGA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Gallus gallus 15378 R-GGA-5340130 https://reactome.org/PathwayBrowser/#/R-GGA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Gallus gallus 15378 R-GGA-5340226 https://reactome.org/PathwayBrowser/#/R-GGA-5340226 CYGB dioxygenates NO IEA Gallus gallus 15378 R-GGA-5362518 https://reactome.org/PathwayBrowser/#/R-GGA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Gallus gallus 15378 R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus 15378 R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 15378 R-GGA-5362564 https://reactome.org/PathwayBrowser/#/R-GGA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Gallus gallus 15378 R-GGA-5362721 https://reactome.org/PathwayBrowser/#/R-GGA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Gallus gallus 15378 R-GGA-5419165 https://reactome.org/PathwayBrowser/#/R-GGA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Gallus gallus 15378 R-GGA-5423637 https://reactome.org/PathwayBrowser/#/R-GGA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Gallus gallus 15378 R-GGA-5423664 https://reactome.org/PathwayBrowser/#/R-GGA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Gallus gallus 15378 R-GGA-5423672 https://reactome.org/PathwayBrowser/#/R-GGA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Gallus gallus 15378 R-GGA-5423678 https://reactome.org/PathwayBrowser/#/R-GGA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Gallus gallus 15378 R-GGA-548818 https://reactome.org/PathwayBrowser/#/R-GGA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Gallus gallus 15378 R-GGA-548831 https://reactome.org/PathwayBrowser/#/R-GGA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Gallus gallus 15378 R-GGA-5652172 https://reactome.org/PathwayBrowser/#/R-GGA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Gallus gallus 15378 R-GGA-5652195 https://reactome.org/PathwayBrowser/#/R-GGA-5652195 SORD oxidizes D-sorbitol to Fru IEA Gallus gallus 15378 R-GGA-5661240 https://reactome.org/PathwayBrowser/#/R-GGA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Gallus gallus 15378 R-GGA-5661256 https://reactome.org/PathwayBrowser/#/R-GGA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Gallus gallus 15378 R-GGA-5661290 https://reactome.org/PathwayBrowser/#/R-GGA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Gallus gallus 15378 R-GGA-5662471 https://reactome.org/PathwayBrowser/#/R-GGA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Gallus gallus 15378 R-GGA-5662662 https://reactome.org/PathwayBrowser/#/R-GGA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Gallus gallus 15378 R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus 15378 R-GGA-5668718 https://reactome.org/PathwayBrowser/#/R-GGA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 15378 R-GGA-5668731 https://reactome.org/PathwayBrowser/#/R-GGA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 15378 R-GGA-5678327 https://reactome.org/PathwayBrowser/#/R-GGA-5678327 MIOX oxidises Ins to GlcA IEA Gallus gallus 15378 R-GGA-5690565 https://reactome.org/PathwayBrowser/#/R-GGA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15378 R-GGA-5691107 https://reactome.org/PathwayBrowser/#/R-GGA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Gallus gallus 15378 R-GGA-5692237 https://reactome.org/PathwayBrowser/#/R-GGA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Gallus gallus 15378 R-GGA-5692261 https://reactome.org/PathwayBrowser/#/R-GGA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Gallus gallus 15378 R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus 15378 R-GGA-5693347 https://reactome.org/PathwayBrowser/#/R-GGA-5693347 CRYM reduces P2C to PPCA IEA Gallus gallus 15378 R-GGA-5693390 https://reactome.org/PathwayBrowser/#/R-GGA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Gallus gallus 15378 R-GGA-5693681 https://reactome.org/PathwayBrowser/#/R-GGA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Gallus gallus 15378 R-GGA-5693691 https://reactome.org/PathwayBrowser/#/R-GGA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Gallus gallus 15378 R-GGA-5693761 https://reactome.org/PathwayBrowser/#/R-GGA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Gallus gallus 15378 R-GGA-5694018 https://reactome.org/PathwayBrowser/#/R-GGA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Gallus gallus 15378 R-GGA-5694462 https://reactome.org/PathwayBrowser/#/R-GGA-5694462 ABHD6,12 hydrolyse 3AG IEA Gallus gallus 15378 R-GGA-5696080 https://reactome.org/PathwayBrowser/#/R-GGA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Gallus gallus 15378 R-GGA-5696101 https://reactome.org/PathwayBrowser/#/R-GGA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Gallus gallus 15378 R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 15378 R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 15378 R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 15378 R-GGA-5696457 https://reactome.org/PathwayBrowser/#/R-GGA-5696457 BDH2 dehydrogenates 3HBA IEA Gallus gallus 15378 R-GGA-5696822 https://reactome.org/PathwayBrowser/#/R-GGA-5696822 AKR1B15 reduces EST17b to E1 IEA Gallus gallus 15378 R-GGA-5696838 https://reactome.org/PathwayBrowser/#/R-GGA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Gallus gallus 15378 R-GGA-597628 https://reactome.org/PathwayBrowser/#/R-GGA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Gallus gallus 15378 R-GGA-6783221 https://reactome.org/PathwayBrowser/#/R-GGA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Gallus gallus 15378 R-GGA-6783939 https://reactome.org/PathwayBrowser/#/R-GGA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 15378 R-GGA-6783955 https://reactome.org/PathwayBrowser/#/R-GGA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 15378 R-GGA-6784399 https://reactome.org/PathwayBrowser/#/R-GGA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Gallus gallus 15378 R-GGA-6785933 https://reactome.org/PathwayBrowser/#/R-GGA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Gallus gallus 15378 R-GGA-6786239 https://reactome.org/PathwayBrowser/#/R-GGA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Gallus gallus 15378 R-GGA-6786720 https://reactome.org/PathwayBrowser/#/R-GGA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Gallus gallus 15378 R-GGA-6787642 https://reactome.org/PathwayBrowser/#/R-GGA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Gallus gallus 15378 R-GGA-6788999 https://reactome.org/PathwayBrowser/#/R-GGA-6788999 HV1-mediated H+ transfer IEA Gallus gallus 15378 R-GGA-6789031 https://reactome.org/PathwayBrowser/#/R-GGA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 15378 R-GGA-6789092 https://reactome.org/PathwayBrowser/#/R-GGA-6789092 NOX2 generates superoxide anion from oxygen IEA Gallus gallus 15378 R-GGA-6789126 https://reactome.org/PathwayBrowser/#/R-GGA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 15378 R-GGA-6793590 https://reactome.org/PathwayBrowser/#/R-GGA-6793590 LIPT2 transfers octanoyl group to GCSH IEA Gallus gallus 15378 R-GGA-6793591 https://reactome.org/PathwayBrowser/#/R-GGA-6793591 LIAS synthesizes lipoyl-GCSH IEA Gallus gallus 15378 R-GGA-6799495 https://reactome.org/PathwayBrowser/#/R-GGA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Gallus gallus 15378 R-GGA-6799722 https://reactome.org/PathwayBrowser/#/R-GGA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Gallus gallus 15378 R-GGA-6801342 https://reactome.org/PathwayBrowser/#/R-GGA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Gallus gallus 15378 R-GGA-6803771 https://reactome.org/PathwayBrowser/#/R-GGA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Gallus gallus 15378 R-GGA-6806647 https://reactome.org/PathwayBrowser/#/R-GGA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Gallus gallus 15378 R-GGA-6806831 https://reactome.org/PathwayBrowser/#/R-GGA-6806831 CYB5Rs reduce MetHb to HbA IEA Gallus gallus 15378 R-GGA-6806967 https://reactome.org/PathwayBrowser/#/R-GGA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Gallus gallus 15378 R-GGA-6807053 https://reactome.org/PathwayBrowser/#/R-GGA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Gallus gallus 15378 R-GGA-6807055 https://reactome.org/PathwayBrowser/#/R-GGA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Gallus gallus 15378 R-GGA-6807064 https://reactome.org/PathwayBrowser/#/R-GGA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Gallus gallus 15378 R-GGA-6807557 https://reactome.org/PathwayBrowser/#/R-GGA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Gallus gallus 15378 R-GGA-6807826 https://reactome.org/PathwayBrowser/#/R-GGA-6807826 LDHAL6B reduces PYR to LACT IEA Gallus gallus 15378 R-GGA-6808464 https://reactome.org/PathwayBrowser/#/R-GGA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Gallus gallus 15378 R-GGA-6808487 https://reactome.org/PathwayBrowser/#/R-GGA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Gallus gallus 15378 R-GGA-6809264 https://reactome.org/PathwayBrowser/#/R-GGA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 15378 R-GGA-6809287 https://reactome.org/PathwayBrowser/#/R-GGA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Gallus gallus 15378 R-GGA-6809810 https://reactome.org/PathwayBrowser/#/R-GGA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Gallus gallus 15378 R-GGA-6813749 https://reactome.org/PathwayBrowser/#/R-GGA-6813749 ALDH1A1 oxidises GA to DGA IEA Gallus gallus 15378 R-GGA-70333 https://reactome.org/PathwayBrowser/#/R-GGA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Gallus gallus 15378 R-GGA-70420 https://reactome.org/PathwayBrowser/#/R-GGA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Gallus gallus 15378 R-GGA-70449 https://reactome.org/PathwayBrowser/#/R-GGA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Gallus gallus 15378 R-GGA-70467 https://reactome.org/PathwayBrowser/#/R-GGA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Gallus gallus 15378 R-GGA-70482 https://reactome.org/PathwayBrowser/#/R-GGA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Gallus gallus 15378 R-GGA-70510 https://reactome.org/PathwayBrowser/#/R-GGA-70510 LDH tetramer oxidises LACT to PYR IEA Gallus gallus 15378 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Gallus gallus 15378 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Gallus gallus 15378 R-GGA-70664 https://reactome.org/PathwayBrowser/#/R-GGA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 15378 R-GGA-70670 https://reactome.org/PathwayBrowser/#/R-GGA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Gallus gallus 15378 R-GGA-70679 https://reactome.org/PathwayBrowser/#/R-GGA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Gallus gallus 15378 R-GGA-70837 https://reactome.org/PathwayBrowser/#/R-GGA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Gallus gallus 15378 R-GGA-70885 https://reactome.org/PathwayBrowser/#/R-GGA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Gallus gallus 15378 R-GGA-70893 https://reactome.org/PathwayBrowser/#/R-GGA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Gallus gallus 15378 R-GGA-70906 https://reactome.org/PathwayBrowser/#/R-GGA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Gallus gallus 15378 R-GGA-70938 https://reactome.org/PathwayBrowser/#/R-GGA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Gallus gallus 15378 R-GGA-70940 https://reactome.org/PathwayBrowser/#/R-GGA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Gallus gallus 15378 R-GGA-70941 https://reactome.org/PathwayBrowser/#/R-GGA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Gallus gallus 15378 R-GGA-70975 https://reactome.org/PathwayBrowser/#/R-GGA-70975 CS acetylates OA to citrate IEA Gallus gallus 15378 R-GGA-70979 https://reactome.org/PathwayBrowser/#/R-GGA-70979 MDH2 dimer dehydrogenates MAL IEA Gallus gallus 15378 R-GGA-71130 https://reactome.org/PathwayBrowser/#/R-GGA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Gallus gallus 15378 R-GGA-71164 https://reactome.org/PathwayBrowser/#/R-GGA-71164 HGD dioxygenates homogentisate IEA Gallus gallus 15378 R-GGA-71181 https://reactome.org/PathwayBrowser/#/R-GGA-71181 FAH cleaves 4FAA IEA Gallus gallus 15378 R-GGA-71200 https://reactome.org/PathwayBrowser/#/R-GGA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Gallus gallus 15378 R-GGA-71260 https://reactome.org/PathwayBrowser/#/R-GGA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Gallus gallus 15378 R-GGA-71286 https://reactome.org/PathwayBrowser/#/R-GGA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Gallus gallus 15378 R-GGA-71299 https://reactome.org/PathwayBrowser/#/R-GGA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Gallus gallus 15378 R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus 15378 R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 15378 R-GGA-71682 https://reactome.org/PathwayBrowser/#/R-GGA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 15378 R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 15378 R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus 15378 R-GGA-71723 https://reactome.org/PathwayBrowser/#/R-GGA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Gallus gallus 15378 R-GGA-71849 https://reactome.org/PathwayBrowser/#/R-GGA-71849 LDH tetramer reduces PYR to LACT IEA Gallus gallus 15378 R-GGA-73564 https://reactome.org/PathwayBrowser/#/R-GGA-73564 UMPS dimer decarboxylates OMP to UMP IEA Gallus gallus 15378 R-GGA-73585 https://reactome.org/PathwayBrowser/#/R-GGA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Gallus gallus 15378 R-GGA-73589 https://reactome.org/PathwayBrowser/#/R-GGA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Gallus gallus 15378 R-GGA-73591 https://reactome.org/PathwayBrowser/#/R-GGA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Gallus gallus 15378 R-GGA-73596 https://reactome.org/PathwayBrowser/#/R-GGA-73596 dCMP + H2O => dUMP + NH4+ IEA Gallus gallus 15378 R-GGA-73616 https://reactome.org/PathwayBrowser/#/R-GGA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Gallus gallus 15378 R-GGA-73618 https://reactome.org/PathwayBrowser/#/R-GGA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Gallus gallus 15378 R-GGA-73620 https://reactome.org/PathwayBrowser/#/R-GGA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Gallus gallus 15378 R-GGA-73646 https://reactome.org/PathwayBrowser/#/R-GGA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Gallus gallus 15378 R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus 15378 R-GGA-73666 https://reactome.org/PathwayBrowser/#/R-GGA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Gallus gallus 15378 R-GGA-73792 https://reactome.org/PathwayBrowser/#/R-GGA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Gallus gallus 15378 R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus 15378 R-GGA-73805 https://reactome.org/PathwayBrowser/#/R-GGA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Gallus gallus 15378 R-GGA-73806 https://reactome.org/PathwayBrowser/#/R-GGA-73806 AIR + CO2 => CAIR IEA Gallus gallus 15378 R-GGA-73810 https://reactome.org/PathwayBrowser/#/R-GGA-73810 FGAM + ATP => AIR + ADP + Pi IEA Gallus gallus 15378 R-GGA-73813 https://reactome.org/PathwayBrowser/#/R-GGA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Gallus gallus 15378 R-GGA-73814 https://reactome.org/PathwayBrowser/#/R-GGA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Gallus gallus 15378 R-GGA-73912 https://reactome.org/PathwayBrowser/#/R-GGA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Gallus gallus 15378 R-GGA-73920 https://reactome.org/PathwayBrowser/#/R-GGA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Gallus gallus 15378 R-GGA-74255 https://reactome.org/PathwayBrowser/#/R-GGA-74255 Guanine + H2O => Xanthine + NH4+ IEA Gallus gallus 15378 R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus 15378 R-GGA-74872 https://reactome.org/PathwayBrowser/#/R-GGA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Gallus gallus 15378 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 15378 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15378 R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Gallus gallus 15378 R-GGA-75883 https://reactome.org/PathwayBrowser/#/R-GGA-75883 DHRS7B reduces GO3P to HXDG3P IEA Gallus gallus 15378 R-GGA-75889 https://reactome.org/PathwayBrowser/#/R-GGA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Gallus gallus 15378 R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 15378 R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 15378 R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 15378 R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 15378 R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 15378 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 15378 R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 15378 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 15378 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 15378 R-GGA-77254 https://reactome.org/PathwayBrowser/#/R-GGA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Gallus gallus 15378 R-GGA-77283 https://reactome.org/PathwayBrowser/#/R-GGA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Gallus gallus 15378 R-GGA-77303 https://reactome.org/PathwayBrowser/#/R-GGA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Gallus gallus 15378 R-GGA-77312 https://reactome.org/PathwayBrowser/#/R-GGA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Gallus gallus 15378 R-GGA-77323 https://reactome.org/PathwayBrowser/#/R-GGA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Gallus gallus 15378 R-GGA-77331 https://reactome.org/PathwayBrowser/#/R-GGA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Gallus gallus 15378 R-GGA-77342 https://reactome.org/PathwayBrowser/#/R-GGA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Gallus gallus 15378 R-GGA-8847579 https://reactome.org/PathwayBrowser/#/R-GGA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15378 R-GGA-8850846 https://reactome.org/PathwayBrowser/#/R-GGA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-GGA-8850854 https://reactome.org/PathwayBrowser/#/R-GGA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-GGA-8851110 https://reactome.org/PathwayBrowser/#/R-GGA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-GGA-8851129 https://reactome.org/PathwayBrowser/#/R-GGA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-GGA-8862137 https://reactome.org/PathwayBrowser/#/R-GGA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Gallus gallus 15378 R-GGA-8863494 https://reactome.org/PathwayBrowser/#/R-GGA-8863494 ASICs bind STOML3, (STOM) IEA Gallus gallus 15378 R-GGA-8866601 https://reactome.org/PathwayBrowser/#/R-GGA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Gallus gallus 15378 R-GGA-8869606 https://reactome.org/PathwayBrowser/#/R-GGA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Gallus gallus 15378 R-GGA-8869607 https://reactome.org/PathwayBrowser/#/R-GGA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Gallus gallus 15378 R-GGA-8869627 https://reactome.org/PathwayBrowser/#/R-GGA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Gallus gallus 15378 R-GGA-8869633 https://reactome.org/PathwayBrowser/#/R-GGA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Gallus gallus 15378 R-GGA-8870346 https://reactome.org/PathwayBrowser/#/R-GGA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Gallus gallus 15378 R-GGA-8875623 https://reactome.org/PathwayBrowser/#/R-GGA-8875623 SLC25A18,22 import L-Glu, H+ IEA Gallus gallus 15378 R-GGA-8878914 https://reactome.org/PathwayBrowser/#/R-GGA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Gallus gallus 15378 R-GGA-888548 https://reactome.org/PathwayBrowser/#/R-GGA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Gallus gallus 15378 R-GGA-888572 https://reactome.org/PathwayBrowser/#/R-GGA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Gallus gallus 15378 R-GGA-888577 https://reactome.org/PathwayBrowser/#/R-GGA-888577 Synthesis of GABA by GAD2 IEA Gallus gallus 15378 R-GGA-8933635 https://reactome.org/PathwayBrowser/#/R-GGA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Gallus gallus 15378 R-GGA-8936442 https://reactome.org/PathwayBrowser/#/R-GGA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Gallus gallus 15378 R-GGA-8938076 https://reactome.org/PathwayBrowser/#/R-GGA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Gallus gallus 15378 R-GGA-8952873 https://reactome.org/PathwayBrowser/#/R-GGA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Gallus gallus 15378 R-GGA-8954468 https://reactome.org/PathwayBrowser/#/R-GGA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Gallus gallus 15378 R-GGA-8955030 https://reactome.org/PathwayBrowser/#/R-GGA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Gallus gallus 15378 R-GGA-8955760 https://reactome.org/PathwayBrowser/#/R-GGA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Gallus gallus 15378 R-GGA-8956458 https://reactome.org/PathwayBrowser/#/R-GGA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Gallus gallus 15378 R-GGA-8959719 https://reactome.org/PathwayBrowser/#/R-GGA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Gallus gallus 15378 R-GGA-9009950 https://reactome.org/PathwayBrowser/#/R-GGA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Gallus gallus 15378 R-GGA-9011595 https://reactome.org/PathwayBrowser/#/R-GGA-9011595 GSTZ1 dimer dehalogenates DCA IEA Gallus gallus 15378 R-GGA-9012016 https://reactome.org/PathwayBrowser/#/R-GGA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Gallus gallus 15378 R-GGA-9012036 https://reactome.org/PathwayBrowser/#/R-GGA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Gallus gallus 15378 R-GGA-9024993 https://reactome.org/PathwayBrowser/#/R-GGA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Gallus gallus 15378 R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus 15378 R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 15378 R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 15378 R-GGA-9037761 https://reactome.org/PathwayBrowser/#/R-GGA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Gallus gallus 15378 R-GGA-917811 https://reactome.org/PathwayBrowser/#/R-GGA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Gallus gallus 15378 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus 15378 R-GGA-917891 https://reactome.org/PathwayBrowser/#/R-GGA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Gallus gallus 15378 R-GGA-917933 https://reactome.org/PathwayBrowser/#/R-GGA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Gallus gallus 15378 R-GGA-937311 https://reactome.org/PathwayBrowser/#/R-GGA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Gallus gallus 15378 R-GGA-9620103 https://reactome.org/PathwayBrowser/#/R-GGA-9620103 ALDH2 transforms GTN to NO IEA Gallus gallus 15378 R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-GGA-9650165 https://reactome.org/PathwayBrowser/#/R-GGA-9650165 ASIC trimers bind H+ IEA Gallus gallus 15378 R-GGA-9705713 https://reactome.org/PathwayBrowser/#/R-GGA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Gallus gallus 15378 R-GGA-9705714 https://reactome.org/PathwayBrowser/#/R-GGA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Gallus gallus 15378 R-GGA-9709098 https://reactome.org/PathwayBrowser/#/R-GGA-9709098 DHFR dimer reduces FOLA to DHF IEA Gallus gallus 15378 R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 15378 R-GGA-9727349 https://reactome.org/PathwayBrowser/#/R-GGA-9727349 XDH dehydrogenates xanthine to form urate IEA Gallus gallus 15378 R-GGA-9731228 https://reactome.org/PathwayBrowser/#/R-GGA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Gallus gallus 15378 R-GGA-9731590 https://reactome.org/PathwayBrowser/#/R-GGA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Gallus gallus 15378 R-GGA-9731613 https://reactome.org/PathwayBrowser/#/R-GGA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Gallus gallus 15378 R-GGA-9731632 https://reactome.org/PathwayBrowser/#/R-GGA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Gallus gallus 15378 R-GGA-9731661 https://reactome.org/PathwayBrowser/#/R-GGA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Gallus gallus 15378 R-GGA-9748945 https://reactome.org/PathwayBrowser/#/R-GGA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Gallus gallus 15378 R-GGA-9748957 https://reactome.org/PathwayBrowser/#/R-GGA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Gallus gallus 15378 R-GGA-9748979 https://reactome.org/PathwayBrowser/#/R-GGA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Gallus gallus 15378 R-GGA-9748983 https://reactome.org/PathwayBrowser/#/R-GGA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Gallus gallus 15378 R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 15378 R-GGA-9749609 https://reactome.org/PathwayBrowser/#/R-GGA-9749609 BCHE hydrolyzes ASA- IEA Gallus gallus 15378 R-GGA-9749647 https://reactome.org/PathwayBrowser/#/R-GGA-9749647 CES2 hydrolyzes ASA- IEA Gallus gallus 15378 R-GGA-9749792 https://reactome.org/PathwayBrowser/#/R-GGA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Gallus gallus 15378 R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus 15378 R-GGA-9755937 https://reactome.org/PathwayBrowser/#/R-GGA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Gallus gallus 15378 R-GGA-9756134 https://reactome.org/PathwayBrowser/#/R-GGA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Gallus gallus 15378 R-GGA-9756138 https://reactome.org/PathwayBrowser/#/R-GGA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Gallus gallus 15378 R-GGA-9756156 https://reactome.org/PathwayBrowser/#/R-GGA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Gallus gallus 15378 R-GGA-9756162 https://reactome.org/PathwayBrowser/#/R-GGA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Gallus gallus 15378 R-GGA-9756169 https://reactome.org/PathwayBrowser/#/R-GGA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Gallus gallus 15378 R-GGA-9756177 https://reactome.org/PathwayBrowser/#/R-GGA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Gallus gallus 15378 R-GGA-9756180 https://reactome.org/PathwayBrowser/#/R-GGA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Gallus gallus 15378 R-GGA-9756183 https://reactome.org/PathwayBrowser/#/R-GGA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Gallus gallus 15378 R-GGA-975629 https://reactome.org/PathwayBrowser/#/R-GGA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Gallus gallus 15378 R-GGA-9757706 https://reactome.org/PathwayBrowser/#/R-GGA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Gallus gallus 15378 R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 15378 R-GGA-9758674 https://reactome.org/PathwayBrowser/#/R-GGA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Gallus gallus 15378 R-GGA-9759259 https://reactome.org/PathwayBrowser/#/R-GGA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Gallus gallus 15378 R-GGA-9759549 https://reactome.org/PathwayBrowser/#/R-GGA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Gallus gallus 15378 R-GGA-9760094 https://reactome.org/PathwayBrowser/#/R-GGA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Gallus gallus 15378 R-GGA-9794270 https://reactome.org/PathwayBrowser/#/R-GGA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Gallus gallus 15378 R-GGA-9837337 https://reactome.org/PathwayBrowser/#/R-GGA-9837337 DCAKD phosphorylates DP-CoA IEA Gallus gallus 15378 R-GGA-9843721 https://reactome.org/PathwayBrowser/#/R-GGA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Gallus gallus 15378 R-GGA-9844587 https://reactome.org/PathwayBrowser/#/R-GGA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Gallus gallus 15378 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 15378 R-GGA-9845538 https://reactome.org/PathwayBrowser/#/R-GGA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Gallus gallus 15378 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 15378 R-GGA-9846305 https://reactome.org/PathwayBrowser/#/R-GGA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Gallus gallus 15378 R-GGA-9846477 https://reactome.org/PathwayBrowser/#/R-GGA-9846477 A4GALT transfers galactose to LacCer IEA Gallus gallus 15378 R-GGA-9846501 https://reactome.org/PathwayBrowser/#/R-GGA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Gallus gallus 15378 R-GGA-9851347 https://reactome.org/PathwayBrowser/#/R-GGA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Gallus gallus 15378 R-GGA-9853499 https://reactome.org/PathwayBrowser/#/R-GGA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 15378 R-GGA-9854415 https://reactome.org/PathwayBrowser/#/R-GGA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Gallus gallus 15378 R-GGA-9856871 https://reactome.org/PathwayBrowser/#/R-GGA-9856871 MDH1 reduces OA IEA Gallus gallus 15378 R-GGA-9861616 https://reactome.org/PathwayBrowser/#/R-GGA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 15378 R-GGA-9861642 https://reactome.org/PathwayBrowser/#/R-GGA-9861642 NEK1 phosphorylates ME1 IEA Gallus gallus 15378 R-GGA-9861660 https://reactome.org/PathwayBrowser/#/R-GGA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Gallus gallus 15378 R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus 15378 R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 15378 R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 15378 R-HSA-109343 https://reactome.org/PathwayBrowser/#/R-HSA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA TAS Homo sapiens 15378 R-HSA-111524 https://reactome.org/PathwayBrowser/#/R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] TAS Homo sapiens 15378 R-HSA-1222353 https://reactome.org/PathwayBrowser/#/R-HSA-1222353 Protonation of superoxide TAS Homo sapiens 15378 R-HSA-1222376 https://reactome.org/PathwayBrowser/#/R-HSA-1222376 NOX2 generates superoxide from oxygen TAS Homo sapiens 15378 R-HSA-1222384 https://reactome.org/PathwayBrowser/#/R-HSA-1222384 Glutathione scavenges nitrosyl TAS Homo sapiens 15378 R-HSA-1222399 https://reactome.org/PathwayBrowser/#/R-HSA-1222399 Iron is reduced and separates from mycobactin IEA Homo sapiens 15378 R-HSA-1222412 https://reactome.org/PathwayBrowser/#/R-HSA-1222412 lpdC dimer reactivates dlaT TAS Homo sapiens 15378 R-HSA-1222462 https://reactome.org/PathwayBrowser/#/R-HSA-1222462 SodB reduces superoxide to H2O2 TAS Homo sapiens 15378 R-HSA-1222469 https://reactome.org/PathwayBrowser/#/R-HSA-1222469 SodC reduces superoxide to H2O2 TAS Homo sapiens 15378 R-HSA-1222485 https://reactome.org/PathwayBrowser/#/R-HSA-1222485 TrxB reactivates TrxA TAS Homo sapiens 15378 R-HSA-1222516 https://reactome.org/PathwayBrowser/#/R-HSA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase TAS Homo sapiens 15378 R-HSA-1222583 https://reactome.org/PathwayBrowser/#/R-HSA-1222583 MscR reduces nitrosomycothiol to ammonia TAS Homo sapiens 15378 R-HSA-1222594 https://reactome.org/PathwayBrowser/#/R-HSA-1222594 Mycothiol scavenges nitrosyl TAS Homo sapiens 15378 R-HSA-1236967 https://reactome.org/PathwayBrowser/#/R-HSA-1236967 Alkalization of the phagosomal lumen by NOX2 TAS Homo sapiens 15378 R-HSA-1237045 https://reactome.org/PathwayBrowser/#/R-HSA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton TAS Homo sapiens 15378 R-HSA-1237047 https://reactome.org/PathwayBrowser/#/R-HSA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- TAS Homo sapiens 15378 R-HSA-1237059 https://reactome.org/PathwayBrowser/#/R-HSA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 TAS Homo sapiens 15378 R-HSA-1237081 https://reactome.org/PathwayBrowser/#/R-HSA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide TAS Homo sapiens 15378 R-HSA-1237129 https://reactome.org/PathwayBrowser/#/R-HSA-1237129 Acireductone is created TAS Homo sapiens 15378 R-HSA-1237325 https://reactome.org/PathwayBrowser/#/R-HSA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen TAS Homo sapiens 15378 R-HSA-1247668 https://reactome.org/PathwayBrowser/#/R-HSA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 TAS Homo sapiens 15378 R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 15378 R-HSA-140359 https://reactome.org/PathwayBrowser/#/R-HSA-140359 PGG2 is reduced to PGH2 by PTGS1 TAS Homo sapiens 15378 R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 15378 R-HSA-1475017 https://reactome.org/PathwayBrowser/#/R-HSA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) TAS Homo sapiens 15378 R-HSA-1475022 https://reactome.org/PathwayBrowser/#/R-HSA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) TAS Homo sapiens 15378 R-HSA-1475025 https://reactome.org/PathwayBrowser/#/R-HSA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) TAS Homo sapiens 15378 R-HSA-1475026 https://reactome.org/PathwayBrowser/#/R-HSA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) TAS Homo sapiens 15378 R-HSA-1475028 https://reactome.org/PathwayBrowser/#/R-HSA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) TAS Homo sapiens 15378 R-HSA-1475032 https://reactome.org/PathwayBrowser/#/R-HSA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) TAS Homo sapiens 15378 R-HSA-1475435 https://reactome.org/PathwayBrowser/#/R-HSA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- TAS Homo sapiens 15378 R-HSA-1475436 https://reactome.org/PathwayBrowser/#/R-HSA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 TAS Homo sapiens 15378 R-HSA-1497794 https://reactome.org/PathwayBrowser/#/R-HSA-1497794 Salvage - BH2 is reduced to BH4 by DHFR IEA Homo sapiens 15378 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 15378 R-HSA-1497869 https://reactome.org/PathwayBrowser/#/R-HSA-1497869 Salvage - Sepiapterin is reduced to BH2 TAS Homo sapiens 15378 R-HSA-1562603 https://reactome.org/PathwayBrowser/#/R-HSA-1562603 BfrB stores iron TAS Homo sapiens 15378 R-HSA-1562604 https://reactome.org/PathwayBrowser/#/R-HSA-1562604 BfrA stores iron TAS Homo sapiens 15378 R-HSA-1562626 https://reactome.org/PathwayBrowser/#/R-HSA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) TAS Homo sapiens 15378 R-HSA-156526 https://reactome.org/PathwayBrowser/#/R-HSA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO TAS Homo sapiens 15378 R-HSA-158609 https://reactome.org/PathwayBrowser/#/R-HSA-158609 TPMT transfers CH3 from AdoMet to 6MP TAS Homo sapiens 15378 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 15378 R-HSA-1605797 https://reactome.org/PathwayBrowser/#/R-HSA-1605797 SMPD1 hydrolyzes SPHM TAS Homo sapiens 15378 R-HSA-1606273 https://reactome.org/PathwayBrowser/#/R-HSA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) TAS Homo sapiens 15378 R-HSA-1606288 https://reactome.org/PathwayBrowser/#/R-HSA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) TAS Homo sapiens 15378 R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 15378 R-HSA-1614362 https://reactome.org/PathwayBrowser/#/R-HSA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases TAS Homo sapiens 15378 R-HSA-1614605 https://reactome.org/PathwayBrowser/#/R-HSA-1614605 Persulfide sulfur is dioxygenated TAS Homo sapiens 15378 R-HSA-1614665 https://reactome.org/PathwayBrowser/#/R-HSA-1614665 SQR oxidizes sulfide to bound persulfide IEA Homo sapiens 15378 R-HSA-162730 https://reactome.org/PathwayBrowser/#/R-HSA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP TAS Homo sapiens 15378 R-HSA-163120 https://reactome.org/PathwayBrowser/#/R-HSA-163120 Disassociation of Telomerase RNP and the Chromosome End TAS Homo sapiens 15378 R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 15378 R-HSA-163217 https://reactome.org/PathwayBrowser/#/R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 TAS Homo sapiens 15378 R-HSA-163672 https://reactome.org/PathwayBrowser/#/R-HSA-163672 Phosphorylation of ChREBP at Thr(653) by PKA IEA Homo sapiens 15378 R-HSA-163676 https://reactome.org/PathwayBrowser/#/R-HSA-163676 Phosphorylation of pChREBP (Thr 653) at Ser(196) by PKA IEA Homo sapiens 15378 R-HSA-163691 https://reactome.org/PathwayBrowser/#/R-HSA-163691 Phosphorylation of ChREBP at Serine 556 by AMPK IEA Homo sapiens 15378 R-HSA-163773 https://reactome.org/PathwayBrowser/#/R-HSA-163773 Phosphorylation of PF2K-Pase by PKA catalytic subunit IEA Homo sapiens 15378 R-HSA-1638104 https://reactome.org/PathwayBrowser/#/R-HSA-1638104 UGCG transfers glucose to ceramide TAS Homo sapiens 15378 R-HSA-1638845 https://reactome.org/PathwayBrowser/#/R-HSA-1638845 CERK phosphorylates CERA to form C1P TAS Homo sapiens 15378 R-HSA-1640164 https://reactome.org/PathwayBrowser/#/R-HSA-1640164 ENPP7 hydrolyzes sphingomyelin TAS Homo sapiens 15378 R-HSA-164151 https://reactome.org/PathwayBrowser/#/R-HSA-164151 LKB1 phosphorylates the alpha subunit of AMPK heterotrimer IEA Homo sapiens 15378 R-HSA-164651 https://reactome.org/PathwayBrowser/#/R-HSA-164651 Electron transfer from ubiquinol to cytochrome c of complex III TAS Homo sapiens 15378 R-HSA-164834 https://reactome.org/PathwayBrowser/#/R-HSA-164834 Enzyme-bound ATP is released TAS Homo sapiens 15378 R-HSA-1655453 https://reactome.org/PathwayBrowser/#/R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU TAS Homo sapiens 15378 R-HSA-1655879 https://reactome.org/PathwayBrowser/#/R-HSA-1655879 Thiosulfate can transfer its sulfur atom to glutathione TAS Homo sapiens 15378 R-HSA-166219 https://reactome.org/PathwayBrowser/#/R-HSA-166219 FA anion picks up a proton TAS Homo sapiens 15378 R-HSA-166223 https://reactome.org/PathwayBrowser/#/R-HSA-166223 The proton is delivered to the matrix side TAS Homo sapiens 15378 R-HSA-1678920 https://reactome.org/PathwayBrowser/#/R-HSA-1678920 TLR processing at low pH TAS Homo sapiens 15378 R-HSA-168299 https://reactome.org/PathwayBrowser/#/R-HSA-168299 Ribonucleoprotein release from M1 proteins TAS Homo sapiens 15378 R-HSA-168313 https://reactome.org/PathwayBrowser/#/R-HSA-168313 Virion-associated M2 protein mediated ion infusion TAS Homo sapiens 15378 R-HSA-170026 https://reactome.org/PathwayBrowser/#/R-HSA-170026 Protons are translocated from the intermembrane space to the matrix TAS Homo sapiens 15378 R-HSA-173597 https://reactome.org/PathwayBrowser/#/R-HSA-173597 UDP-glucose is oxidised to UDP-glucuronate TAS Homo sapiens 15378 R-HSA-174389 https://reactome.org/PathwayBrowser/#/R-HSA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS TAS Homo sapiens 15378 R-HSA-174392 https://reactome.org/PathwayBrowser/#/R-HSA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS TAS Homo sapiens 15378 R-HSA-174438 https://reactome.org/PathwayBrowser/#/R-HSA-174438 Formation of the Flap Intermediate on the C-strand TAS Homo sapiens 15378 R-HSA-189421 https://reactome.org/PathwayBrowser/#/R-HSA-189421 CPO transforms COPRO3 to PPGEN9 TAS Homo sapiens 15378 R-HSA-189425 https://reactome.org/PathwayBrowser/#/R-HSA-189425 UROD decarboxylates URO3 to COPRO3 TAS Homo sapiens 15378 R-HSA-189439 https://reactome.org/PathwayBrowser/#/R-HSA-189439 ALAD condenses 2 dALAs to form PBG TAS Homo sapiens 15378 R-HSA-189442 https://reactome.org/PathwayBrowser/#/R-HSA-189442 ALAS condenses SUCC-CoA and Gly to form dALA TAS Homo sapiens 15378 R-HSA-189465 https://reactome.org/PathwayBrowser/#/R-HSA-189465 FECH binds Fe2+ to PRIN9 to form heme TAS Homo sapiens 15378 R-HSA-190182 https://reactome.org/PathwayBrowser/#/R-HSA-190182 UROD decarboxylates URO1 to COPRO1 TAS Homo sapiens 15378 R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 15378 R-HSA-191323 https://reactome.org/PathwayBrowser/#/R-HSA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA TAS Homo sapiens 15378 R-HSA-191352 https://reactome.org/PathwayBrowser/#/R-HSA-191352 HMGCR dimer reduces bHMG-CoA to MVA TAS Homo sapiens 15378 R-HSA-191402 https://reactome.org/PathwayBrowser/#/R-HSA-191402 Reduction of presqualene diphosphate to form squalene TAS Homo sapiens 15378 R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 15378 R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 15378 R-HSA-191999 https://reactome.org/PathwayBrowser/#/R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol TAS Homo sapiens 15378 R-HSA-192033 https://reactome.org/PathwayBrowser/#/R-HSA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one TAS Homo sapiens 15378 R-HSA-192036 https://reactome.org/PathwayBrowser/#/R-HSA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol TAS Homo sapiens 15378 R-HSA-192042 https://reactome.org/PathwayBrowser/#/R-HSA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 15378 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 15378 R-HSA-192054 https://reactome.org/PathwayBrowser/#/R-HSA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) TAS Homo sapiens 15378 R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 15378 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 15378 R-HSA-192067 https://reactome.org/PathwayBrowser/#/R-HSA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one TAS Homo sapiens 15378 R-HSA-192097 https://reactome.org/PathwayBrowser/#/R-HSA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one TAS Homo sapiens 15378 R-HSA-192123 https://reactome.org/PathwayBrowser/#/R-HSA-192123 CYP27A1 27-hydroxylates CHOL TAS Homo sapiens 15378 R-HSA-192157 https://reactome.org/PathwayBrowser/#/R-HSA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE TAS Homo sapiens 15378 R-HSA-192160 https://reactome.org/PathwayBrowser/#/R-HSA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol TAS Homo sapiens 15378 R-HSA-192178 https://reactome.org/PathwayBrowser/#/R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL TAS Homo sapiens 15378 R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 15378 R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 15378 R-HSA-193064 https://reactome.org/PathwayBrowser/#/R-HSA-193064 HSD17B3-like proteins reducde ANDST to TEST TAS Homo sapiens 15378 R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 15378 R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 15378 R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 15378 R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 15378 R-HSA-193073 https://reactome.org/PathwayBrowser/#/R-HSA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST TAS Homo sapiens 15378 R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 15378 R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 15378 R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 15378 R-HSA-193393 https://reactome.org/PathwayBrowser/#/R-HSA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol TAS Homo sapiens 15378 R-HSA-193455 https://reactome.org/PathwayBrowser/#/R-HSA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 15378 R-HSA-193460 https://reactome.org/PathwayBrowser/#/R-HSA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) TAS Homo sapiens 15378 R-HSA-193497 https://reactome.org/PathwayBrowser/#/R-HSA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al TAS Homo sapiens 15378 R-HSA-193508 https://reactome.org/PathwayBrowser/#/R-HSA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 15378 R-HSA-193709 https://reactome.org/PathwayBrowser/#/R-HSA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL TAS Homo sapiens 15378 R-HSA-193713 https://reactome.org/PathwayBrowser/#/R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) TAS Homo sapiens 15378 R-HSA-193719 https://reactome.org/PathwayBrowser/#/R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 15378 R-HSA-193737 https://reactome.org/PathwayBrowser/#/R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) TAS Homo sapiens 15378 R-HSA-193746 https://reactome.org/PathwayBrowser/#/R-HSA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one TAS Homo sapiens 15378 R-HSA-193755 https://reactome.org/PathwayBrowser/#/R-HSA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one TAS Homo sapiens 15378 R-HSA-193758 https://reactome.org/PathwayBrowser/#/R-HSA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol TAS Homo sapiens 15378 R-HSA-193780 https://reactome.org/PathwayBrowser/#/R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al TAS Homo sapiens 15378 R-HSA-193781 https://reactome.org/PathwayBrowser/#/R-HSA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol TAS Homo sapiens 15378 R-HSA-193787 https://reactome.org/PathwayBrowser/#/R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol TAS Homo sapiens 15378 R-HSA-193789 https://reactome.org/PathwayBrowser/#/R-HSA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one TAS Homo sapiens 15378 R-HSA-193792 https://reactome.org/PathwayBrowser/#/R-HSA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 15378 R-HSA-193800 https://reactome.org/PathwayBrowser/#/R-HSA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol TAS Homo sapiens 15378 R-HSA-193816 https://reactome.org/PathwayBrowser/#/R-HSA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one TAS Homo sapiens 15378 R-HSA-193821 https://reactome.org/PathwayBrowser/#/R-HSA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one TAS Homo sapiens 15378 R-HSA-193824 https://reactome.org/PathwayBrowser/#/R-HSA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one TAS Homo sapiens 15378 R-HSA-193841 https://reactome.org/PathwayBrowser/#/R-HSA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol TAS Homo sapiens 15378 R-HSA-193845 https://reactome.org/PathwayBrowser/#/R-HSA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE TAS Homo sapiens 15378 R-HSA-193964 https://reactome.org/PathwayBrowser/#/R-HSA-193964 CYP21A2 21-hydroxylates PROG TAS Homo sapiens 15378 R-HSA-193965 https://reactome.org/PathwayBrowser/#/R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO TAS Homo sapiens 15378 R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 15378 R-HSA-193995 https://reactome.org/PathwayBrowser/#/R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST TAS Homo sapiens 15378 R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 15378 R-HSA-194017 https://reactome.org/PathwayBrowser/#/R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST TAS Homo sapiens 15378 R-HSA-194023 https://reactome.org/PathwayBrowser/#/R-HSA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR TAS Homo sapiens 15378 R-HSA-194632 https://reactome.org/PathwayBrowser/#/R-HSA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) TAS Homo sapiens 15378 R-HSA-194641 https://reactome.org/PathwayBrowser/#/R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15378 R-HSA-194642 https://reactome.org/PathwayBrowser/#/R-HSA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one TAS Homo sapiens 15378 R-HSA-194669 https://reactome.org/PathwayBrowser/#/R-HSA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15378 R-HSA-194674 https://reactome.org/PathwayBrowser/#/R-HSA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] TAS Homo sapiens 15378 R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 15378 R-HSA-194689 https://reactome.org/PathwayBrowser/#/R-HSA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15378 R-HSA-194698 https://reactome.org/PathwayBrowser/#/R-HSA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] TAS Homo sapiens 15378 R-HSA-194718 https://reactome.org/PathwayBrowser/#/R-HSA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) TAS Homo sapiens 15378 R-HSA-195664 https://reactome.org/PathwayBrowser/#/R-HSA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol TAS Homo sapiens 15378 R-HSA-196060 https://reactome.org/PathwayBrowser/#/R-HSA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol TAS Homo sapiens 15378 R-HSA-196350 https://reactome.org/PathwayBrowser/#/R-HSA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione TAS Homo sapiens 15378 R-HSA-196372 https://reactome.org/PathwayBrowser/#/R-HSA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol TAS Homo sapiens 15378 R-HSA-196402 https://reactome.org/PathwayBrowser/#/R-HSA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol TAS Homo sapiens 15378 R-HSA-196417 https://reactome.org/PathwayBrowser/#/R-HSA-196417 Reduction of desmosterol to cholesterol TAS Homo sapiens 15378 R-HSA-196753 https://reactome.org/PathwayBrowser/#/R-HSA-196753 2xPPCS ligates PPanK with Cys TAS Homo sapiens 15378 R-HSA-196754 https://reactome.org/PathwayBrowser/#/R-HSA-196754 COASY transfers an adenylyl group from ATP to PPANT TAS Homo sapiens 15378 R-HSA-196773 https://reactome.org/PathwayBrowser/#/R-HSA-196773 COASY phosphorylates DP-CoA TAS Homo sapiens 15378 R-HSA-196840 https://reactome.org/PathwayBrowser/#/R-HSA-196840 3xPPCDC:3FMN decarboxylates PPC TAS Homo sapiens 15378 R-HSA-196857 https://reactome.org/PathwayBrowser/#/R-HSA-196857 PANK2 phosphorylates PanK TAS Homo sapiens 15378 R-HSA-196929 https://reactome.org/PathwayBrowser/#/R-HSA-196929 FLAD1 phosphorylates FMN TAS Homo sapiens 15378 R-HSA-196955 https://reactome.org/PathwayBrowser/#/R-HSA-196955 2xENPP1 hydrolyzes FAD to FMN TAS Homo sapiens 15378 R-HSA-196964 https://reactome.org/PathwayBrowser/#/R-HSA-196964 RFK:Mg2+ phosphorylates RIB TAS Homo sapiens 15378 R-HSA-197186 https://reactome.org/PathwayBrowser/#/R-HSA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN TAS Homo sapiens 15378 R-HSA-197268 https://reactome.org/PathwayBrowser/#/R-HSA-197268 QPRT transfers PRIB to QUIN to form NAMN TAS Homo sapiens 15378 R-HSA-197963 https://reactome.org/PathwayBrowser/#/R-HSA-197963 DHFR2 reduces FOLA to DHF TAS Homo sapiens 15378 R-HSA-197972 https://reactome.org/PathwayBrowser/#/R-HSA-197972 DHF is reduced to tetrahydrofolate (THF) TAS Homo sapiens 15378 R-HSA-198824 https://reactome.org/PathwayBrowser/#/R-HSA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme TAS Homo sapiens 15378 R-HSA-199203 https://reactome.org/PathwayBrowser/#/R-HSA-199203 PANK1/3 phosphorylate PanK TAS Homo sapiens 15378 R-HSA-200644 https://reactome.org/PathwayBrowser/#/R-HSA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ TAS Homo sapiens 15378 R-HSA-200676 https://reactome.org/PathwayBrowser/#/R-HSA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG TAS Homo sapiens 15378 R-HSA-200718 https://reactome.org/PathwayBrowser/#/R-HSA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG TAS Homo sapiens 15378 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 15378 R-HSA-204617 https://reactome.org/PathwayBrowser/#/R-HSA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A TAS Homo sapiens 15378 R-HSA-204647 https://reactome.org/PathwayBrowser/#/R-HSA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine TAS Homo sapiens 15378 R-HSA-204662 https://reactome.org/PathwayBrowser/#/R-HSA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A TAS Homo sapiens 15378 R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 15378 R-HSA-209772 https://reactome.org/PathwayBrowser/#/R-HSA-209772 Thyroxine is deiodinated to triiodothyronine TAS Homo sapiens 15378 R-HSA-209821 https://reactome.org/PathwayBrowser/#/R-HSA-209821 Methylation of N-acetyl-5-HT to form melatonin TAS Homo sapiens 15378 R-HSA-209845 https://reactome.org/PathwayBrowser/#/R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D TAS Homo sapiens 15378 R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 15378 R-HSA-209903 https://reactome.org/PathwayBrowser/#/R-HSA-209903 Noradrenaline is converted to adrenaline TAS Homo sapiens 15378 R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 15378 R-HSA-210404 https://reactome.org/PathwayBrowser/#/R-HSA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ TAS Homo sapiens 15378 R-HSA-211873 https://reactome.org/PathwayBrowser/#/R-HSA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 TAS Homo sapiens 15378 R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 15378 R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 15378 R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 15378 R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 15378 R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 15378 R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 15378 R-HSA-211923 https://reactome.org/PathwayBrowser/#/R-HSA-211923 CYP26C1 4-hydroxylates 9cRA TAS Homo sapiens 15378 R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 15378 R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 15378 R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 15378 R-HSA-211950 https://reactome.org/PathwayBrowser/#/R-HSA-211950 CYP24A1 24-hydroxylates CTL TAS Homo sapiens 15378 R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 15378 R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 15378 R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 15378 R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 15378 R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 15378 R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 15378 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 15378 R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 15378 R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 15378 R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 15378 R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 15378 R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 15378 R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 15378 R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 15378 R-HSA-2161187 https://reactome.org/PathwayBrowser/#/R-HSA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine TAS Homo sapiens 15378 R-HSA-2161549 https://reactome.org/PathwayBrowser/#/R-HSA-2161549 PGH2 is reduced to PGF2a by AKR1C3 TAS Homo sapiens 15378 R-HSA-2161567 https://reactome.org/PathwayBrowser/#/R-HSA-2161567 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 IEA Homo sapiens 15378 R-HSA-2161614 https://reactome.org/PathwayBrowser/#/R-HSA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 TAS Homo sapiens 15378 R-HSA-2161651 https://reactome.org/PathwayBrowser/#/R-HSA-2161651 PGE2 is converted to PGF2a by CBR1 TAS Homo sapiens 15378 R-HSA-2161662 https://reactome.org/PathwayBrowser/#/R-HSA-2161662 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD IEA Homo sapiens 15378 R-HSA-2161692 https://reactome.org/PathwayBrowser/#/R-HSA-2161692 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1 IEA Homo sapiens 15378 R-HSA-2161732 https://reactome.org/PathwayBrowser/#/R-HSA-2161732 TXB2 is converted to 11dh-TXB2 by TXDH TAS Homo sapiens 15378 R-HSA-2161745 https://reactome.org/PathwayBrowser/#/R-HSA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15378 R-HSA-2161776 https://reactome.org/PathwayBrowser/#/R-HSA-2161776 5S-HETE is oxidised to 5-oxoETE by 5-HEDH TAS Homo sapiens 15378 R-HSA-2161779 https://reactome.org/PathwayBrowser/#/R-HSA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD TAS Homo sapiens 15378 R-HSA-2161789 https://reactome.org/PathwayBrowser/#/R-HSA-2161789 15S-HETE is oxidised to 15-oxoETE by 15-HEDH TAS Homo sapiens 15378 R-HSA-2161792 https://reactome.org/PathwayBrowser/#/R-HSA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15378 R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) TAS Homo sapiens 15378 R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 15378 R-HSA-2161844 https://reactome.org/PathwayBrowser/#/R-HSA-2161844 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 IEA Homo sapiens 15378 R-HSA-2161890 https://reactome.org/PathwayBrowser/#/R-HSA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) TAS Homo sapiens 15378 R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) TAS Homo sapiens 15378 R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 15378 R-HSA-2161951 https://reactome.org/PathwayBrowser/#/R-HSA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 TAS Homo sapiens 15378 R-HSA-2161979 https://reactome.org/PathwayBrowser/#/R-HSA-2161979 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH TAS Homo sapiens 15378 R-HSA-2162078 https://reactome.org/PathwayBrowser/#/R-HSA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ TAS Homo sapiens 15378 R-HSA-2162186 https://reactome.org/PathwayBrowser/#/R-HSA-2162186 COQ3 methylates DeMQ10H2 TAS Homo sapiens 15378 R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB IEA Homo sapiens 15378 R-HSA-2162188 https://reactome.org/PathwayBrowser/#/R-HSA-2162188 COQ5 methylates MDMQ10H2 TAS Homo sapiens 15378 R-HSA-2162191 https://reactome.org/PathwayBrowser/#/R-HSA-2162191 Unknown enzyme hydroxylates DMPhOH IEA Homo sapiens 15378 R-HSA-2162193 https://reactome.org/PathwayBrowser/#/R-HSA-2162193 COQ3 methylates DHDB TAS Homo sapiens 15378 R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 15378 R-HSA-2162195 https://reactome.org/PathwayBrowser/#/R-HSA-2162195 Unknown enzyme decarboxylates MHDB IEA Homo sapiens 15378 R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 15378 R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 15378 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 15378 R-HSA-2395512 https://reactome.org/PathwayBrowser/#/R-HSA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) TAS Homo sapiens 15378 R-HSA-2395517 https://reactome.org/PathwayBrowser/#/R-HSA-2395517 NADPH transfers electrons to FDXR TAS Homo sapiens 15378 R-HSA-2395818 https://reactome.org/PathwayBrowser/#/R-HSA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP TAS Homo sapiens 15378 R-HSA-2395849 https://reactome.org/PathwayBrowser/#/R-HSA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 15378 R-HSA-2395869 https://reactome.org/PathwayBrowser/#/R-HSA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 15378 R-HSA-2395872 https://reactome.org/PathwayBrowser/#/R-HSA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP TAS Homo sapiens 15378 R-HSA-2395873 https://reactome.org/PathwayBrowser/#/R-HSA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP TAS Homo sapiens 15378 R-HSA-2395876 https://reactome.org/PathwayBrowser/#/R-HSA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 15378 R-HSA-2395879 https://reactome.org/PathwayBrowser/#/R-HSA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 15378 R-HSA-2395965 https://reactome.org/PathwayBrowser/#/R-HSA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP TAS Homo sapiens 15378 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 15378 R-HSA-2408542 https://reactome.org/PathwayBrowser/#/R-HSA-2408542 GSSeSG is reduced to GSSeH and GSH by GSR IEA Homo sapiens 15378 R-HSA-2408548 https://reactome.org/PathwayBrowser/#/R-HSA-2408548 PAPSe is reduced to SeO3(2-) by PAPSe reductase IEA Homo sapiens 15378 R-HSA-2408556 https://reactome.org/PathwayBrowser/#/R-HSA-2408556 SeO3(2-) combines with GSH to form GSSeSG and GSSG IEA Homo sapiens 15378 R-HSA-2408558 https://reactome.org/PathwayBrowser/#/R-HSA-2408558 SeO3(2-) is reduced to H2Se by TXNRD1 IEA Homo sapiens 15378 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 15378 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 15378 R-HSA-2454081 https://reactome.org/PathwayBrowser/#/R-HSA-2454081 RDH5 oxidises 11cROL to 11cRAL TAS Homo sapiens 15378 R-HSA-2464803 https://reactome.org/PathwayBrowser/#/R-HSA-2464803 RDH8 reduces atRAL to atROL IEA Homo sapiens 15378 R-HSA-2464822 https://reactome.org/PathwayBrowser/#/R-HSA-2464822 RDH12 reduces atRAL to atROL TAS Homo sapiens 15378 R-HSA-2465921 https://reactome.org/PathwayBrowser/#/R-HSA-2465921 11cRDH oxidises 11cROL to 11cRAL TAS Homo sapiens 15378 R-HSA-2465940 https://reactome.org/PathwayBrowser/#/R-HSA-2465940 atRAL is reduced to atROL TAS Homo sapiens 15378 R-HSA-2465941 https://reactome.org/PathwayBrowser/#/R-HSA-2465941 A REH hydrolyses 11cRE to 11cROL IEA Homo sapiens 15378 R-HSA-2466861 https://reactome.org/PathwayBrowser/#/R-HSA-2466861 Defective RDH12 does not reduce atRAL to atROL and causes LCA13 TAS Homo sapiens 15378 R-HSA-2471670 https://reactome.org/PathwayBrowser/#/R-HSA-2471670 Defective RDH12 does not reduce atRAL to atROL TAS Homo sapiens 15378 R-HSA-2509793 https://reactome.org/PathwayBrowser/#/R-HSA-2509793 NUDT16 hydrolyses dIDP to dIMP TAS Homo sapiens 15378 R-HSA-2509816 https://reactome.org/PathwayBrowser/#/R-HSA-2509816 NUDT16 hydrolyses IDP to IMP TAS Homo sapiens 15378 R-HSA-2509827 https://reactome.org/PathwayBrowser/#/R-HSA-2509827 ITPA hydrolyses ITP to IMP TAS Homo sapiens 15378 R-HSA-2509831 https://reactome.org/PathwayBrowser/#/R-HSA-2509831 ITPA hydrolyses XTP to XMP TAS Homo sapiens 15378 R-HSA-2509838 https://reactome.org/PathwayBrowser/#/R-HSA-2509838 ITPA hydrolyses dITP to dIMP TAS Homo sapiens 15378 R-HSA-2534378 https://reactome.org/PathwayBrowser/#/R-HSA-2534378 Hv1 Mediated H+ Permeability TAS Homo sapiens 15378 R-HSA-2564824 https://reactome.org/PathwayBrowser/#/R-HSA-2564824 NADPH reduces NDOR1:CIAPIN1 IEA Homo sapiens 15378 R-HSA-264615 https://reactome.org/PathwayBrowser/#/R-HSA-264615 Loading of acetylcholine in synaptic vesicles TAS Homo sapiens 15378 R-HSA-2671885 https://reactome.org/PathwayBrowser/#/R-HSA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol TAS Homo sapiens 15378 R-HSA-2730692 https://reactome.org/PathwayBrowser/#/R-HSA-2730692 CLCN4/5/6 exchange Cl- for H+ TAS Homo sapiens 15378 R-HSA-2730959 https://reactome.org/PathwayBrowser/#/R-HSA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ TAS Homo sapiens 15378 R-HSA-2731002 https://reactome.org/PathwayBrowser/#/R-HSA-2731002 CLCN3 exchanges Cl- for H+ IEA Homo sapiens 15378 R-HSA-2855252 https://reactome.org/PathwayBrowser/#/R-HSA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL TAS Homo sapiens 15378 R-HSA-2872444 https://reactome.org/PathwayBrowser/#/R-HSA-2872444 SLC9B1/C2 exchange Na+ for H+ TAS Homo sapiens 15378 R-HSA-2872463 https://reactome.org/PathwayBrowser/#/R-HSA-2872463 SLC9C1 exchanges Na+ for H+ IEA Homo sapiens 15378 R-HSA-2889070 https://reactome.org/PathwayBrowser/#/R-HSA-2889070 SLC9B2 exchanges Na+ for H+ TAS Homo sapiens 15378 R-HSA-3095889 https://reactome.org/PathwayBrowser/#/R-HSA-3095889 MMACHC dealkylates RCbl TAS Homo sapiens 15378 R-HSA-3149518 https://reactome.org/PathwayBrowser/#/R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl TAS Homo sapiens 15378 R-HSA-3149519 https://reactome.org/PathwayBrowser/#/R-HSA-3149519 MMACHC decyanates CNCbl TAS Homo sapiens 15378 R-HSA-3159253 https://reactome.org/PathwayBrowser/#/R-HSA-3159253 MMAB adenosylates cob(I)alamin TAS Homo sapiens 15378 R-HSA-3299680 https://reactome.org/PathwayBrowser/#/R-HSA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) TAS Homo sapiens 15378 R-HSA-3299682 https://reactome.org/PathwayBrowser/#/R-HSA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) TAS Homo sapiens 15378 R-HSA-3299691 https://reactome.org/PathwayBrowser/#/R-HSA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) TAS Homo sapiens 15378 R-HSA-3318576 https://reactome.org/PathwayBrowser/#/R-HSA-3318576 Defective MMACHC does not reduce Cbl TAS Homo sapiens 15378 R-HSA-3318590 https://reactome.org/PathwayBrowser/#/R-HSA-3318590 Defective MMACHC does not decyanate CNCbl TAS Homo sapiens 15378 R-HSA-3323050 https://reactome.org/PathwayBrowser/#/R-HSA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH TAS Homo sapiens 15378 R-HSA-3323079 https://reactome.org/PathwayBrowser/#/R-HSA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 15378 R-HSA-349520 https://reactome.org/PathwayBrowser/#/R-HSA-349520 Re-acidification of acetylcholine transport vesicles TAS Homo sapiens 15378 R-HSA-350869 https://reactome.org/PathwayBrowser/#/R-HSA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) TAS Homo sapiens 15378 R-HSA-350901 https://reactome.org/PathwayBrowser/#/R-HSA-350901 Iodide is organified TAS Homo sapiens 15378 R-HSA-352174 https://reactome.org/PathwayBrowser/#/R-HSA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine TAS Homo sapiens 15378 R-HSA-352182 https://reactome.org/PathwayBrowser/#/R-HSA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine TAS Homo sapiens 15378 R-HSA-3560789 https://reactome.org/PathwayBrowser/#/R-HSA-3560789 Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol TAS Homo sapiens 15378 R-HSA-372342 https://reactome.org/PathwayBrowser/#/R-HSA-372342 MPC1:MPC2 imports PYR, H+ to mitochondrial matrix IEA Homo sapiens 15378 R-HSA-372448 https://reactome.org/PathwayBrowser/#/R-HSA-372448 SLC25A12,13 exchange L-Glu and L-Asp TAS Homo sapiens 15378 R-HSA-373867 https://reactome.org/PathwayBrowser/#/R-HSA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-373875 https://reactome.org/PathwayBrowser/#/R-HSA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region TAS Homo sapiens 15378 R-HSA-374916 https://reactome.org/PathwayBrowser/#/R-HSA-374916 Re-acidification of clathrin sculpted monoamine transport vesicle lumen TAS Homo sapiens 15378 R-HSA-375405 https://reactome.org/PathwayBrowser/#/R-HSA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-375417 https://reactome.org/PathwayBrowser/#/R-HSA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine TAS Homo sapiens 15378 R-HSA-3777112 https://reactome.org/PathwayBrowser/#/R-HSA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) TAS Homo sapiens 15378 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15378 R-HSA-380608 https://reactome.org/PathwayBrowser/#/R-HSA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid TAS Homo sapiens 15378 R-HSA-389540 https://reactome.org/PathwayBrowser/#/R-HSA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 15378 R-HSA-389550 https://reactome.org/PathwayBrowser/#/R-HSA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 15378 R-HSA-389609 https://reactome.org/PathwayBrowser/#/R-HSA-389609 ALDH3A2-2 oxidizes pristanal to pristanate TAS Homo sapiens 15378 R-HSA-389826 https://reactome.org/PathwayBrowser/#/R-HSA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ TAS Homo sapiens 15378 R-HSA-389995 https://reactome.org/PathwayBrowser/#/R-HSA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ TAS Homo sapiens 15378 R-HSA-390251 https://reactome.org/PathwayBrowser/#/R-HSA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 15378 R-HSA-390276 https://reactome.org/PathwayBrowser/#/R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA TAS Homo sapiens 15378 R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA TAS Homo sapiens 15378 R-HSA-390425 https://reactome.org/PathwayBrowser/#/R-HSA-390425 FAR1 reduces PalmCoA to HXOL TAS Homo sapiens 15378 R-HSA-390438 https://reactome.org/PathwayBrowser/#/R-HSA-390438 FAR2 reduces PalmCoA to HXOL TAS Homo sapiens 15378 R-HSA-418365 https://reactome.org/PathwayBrowser/#/R-HSA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen TAS Homo sapiens 15378 R-HSA-425577 https://reactome.org/PathwayBrowser/#/R-HSA-425577 Na+-driven Cl-/HCO3- exchanger transport TAS Homo sapiens 15378 R-HSA-425965 https://reactome.org/PathwayBrowser/#/R-HSA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane TAS Homo sapiens 15378 R-HSA-425983 https://reactome.org/PathwayBrowser/#/R-HSA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane TAS Homo sapiens 15378 R-HSA-425994 https://reactome.org/PathwayBrowser/#/R-HSA-425994 Na+/H+ exchanger transport (at cell membrane) TAS Homo sapiens 15378 R-HSA-426015 https://reactome.org/PathwayBrowser/#/R-HSA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) TAS Homo sapiens 15378 R-HSA-426043 https://reactome.org/PathwayBrowser/#/R-HSA-426043 2-AG hydrolysis to arachidonate by MAGL TAS Homo sapiens 15378 R-HSA-427555 https://reactome.org/PathwayBrowser/#/R-HSA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-427910 https://reactome.org/PathwayBrowser/#/R-HSA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen TAS Homo sapiens 15378 R-HSA-427998 https://reactome.org/PathwayBrowser/#/R-HSA-427998 Proton-coupled di- and tri-peptide cotransport TAS Homo sapiens 15378 R-HSA-428007 https://reactome.org/PathwayBrowser/#/R-HSA-428007 Proton-coupled histidine and di-peptide cotransport TAS Homo sapiens 15378 R-HSA-428015 https://reactome.org/PathwayBrowser/#/R-HSA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-428052 https://reactome.org/PathwayBrowser/#/R-HSA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ TAS Homo sapiens 15378 R-HSA-428123 https://reactome.org/PathwayBrowser/#/R-HSA-428123 KDSR reduces 3-ketosphingoid TAS Homo sapiens 15378 R-HSA-428127 https://reactome.org/PathwayBrowser/#/R-HSA-428127 SPTLC complexes transfer acyl-CoA onto serine TAS Homo sapiens 15378 R-HSA-428185 https://reactome.org/PathwayBrowser/#/R-HSA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid TAS Homo sapiens 15378 R-HSA-428259 https://reactome.org/PathwayBrowser/#/R-HSA-428259 DEGS1 dehydrogenates dihydroceramide TAS Homo sapiens 15378 R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 15378 R-HSA-428273 https://reactome.org/PathwayBrowser/#/R-HSA-428273 SPHK1 phosphorylates sphingoid TAS Homo sapiens 15378 R-HSA-428585 https://reactome.org/PathwayBrowser/#/R-HSA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol TAS Homo sapiens 15378 R-HSA-428625 https://reactome.org/PathwayBrowser/#/R-HSA-428625 Vesicular inhibitory amino acid transport TAS Homo sapiens 15378 R-HSA-429101 https://reactome.org/PathwayBrowser/#/R-HSA-429101 HMIT co-transports myo-inositol with a proton TAS Homo sapiens 15378 R-HSA-429157 https://reactome.org/PathwayBrowser/#/R-HSA-429157 ABCC4 accumulation of dense granule contents TAS Homo sapiens 15378 R-HSA-429698 https://reactome.org/PathwayBrowser/#/R-HSA-429698 PRKD1,2,3 phosphorylates CERT1-2 TAS Homo sapiens 15378 R-HSA-429714 https://reactome.org/PathwayBrowser/#/R-HSA-429714 CSNK1G2 phosphorylates p-CERT1-2 TAS Homo sapiens 15378 R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-434650 https://reactome.org/PathwayBrowser/#/R-HSA-434650 MATEs mediate extrusion of xenobiotics TAS Homo sapiens 15378 R-HSA-435171 https://reactome.org/PathwayBrowser/#/R-HSA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages TAS Homo sapiens 15378 R-HSA-435349 https://reactome.org/PathwayBrowser/#/R-HSA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-444393 https://reactome.org/PathwayBrowser/#/R-HSA-444393 RhCG mediates ammonium influx into kidney collecting duct cells TAS Homo sapiens 15378 R-HSA-444419 https://reactome.org/PathwayBrowser/#/R-HSA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells TAS Homo sapiens 15378 R-HSA-444731 https://reactome.org/PathwayBrowser/#/R-HSA-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors TAS Homo sapiens 15378 R-HSA-446277 https://reactome.org/PathwayBrowser/#/R-HSA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells TAS Homo sapiens 15378 R-HSA-446278 https://reactome.org/PathwayBrowser/#/R-HSA-446278 RhBG mediates ammonium influx into kidney collecting duct cells TAS Homo sapiens 15378 R-HSA-450971 https://reactome.org/PathwayBrowser/#/R-HSA-450971 NNT dimer transfers proton from NADPH to NAD+ TAS Homo sapiens 15378 R-HSA-469659 https://reactome.org/PathwayBrowser/#/R-HSA-469659 SRD5A1 dehydrogenates TEST to DHTEST TAS Homo sapiens 15378 R-HSA-504054 https://reactome.org/PathwayBrowser/#/R-HSA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] TAS Homo sapiens 15378 R-HSA-508040 https://reactome.org/PathwayBrowser/#/R-HSA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] TAS Homo sapiens 15378 R-HSA-508369 https://reactome.org/PathwayBrowser/#/R-HSA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ TAS Homo sapiens 15378 R-HSA-508473 https://reactome.org/PathwayBrowser/#/R-HSA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ TAS Homo sapiens 15378 R-HSA-514604 https://reactome.org/PathwayBrowser/#/R-HSA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) TAS Homo sapiens 15378 R-HSA-5210943 https://reactome.org/PathwayBrowser/#/R-HSA-5210943 pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol) TAS Homo sapiens 15378 R-HSA-5210947 https://reactome.org/PathwayBrowser/#/R-HSA-5210947 pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol) TAS Homo sapiens 15378 R-HSA-5218841 https://reactome.org/PathwayBrowser/#/R-HSA-5218841 NADPH oxidase 2 generates superoxide from oxygen TAS Homo sapiens 15378 R-HSA-5228406 https://reactome.org/PathwayBrowser/#/R-HSA-5228406 tetX HC transports tetX LC from target cell endosome membrane into cytosol TAS Homo sapiens 15378 R-HSA-5244404 https://reactome.org/PathwayBrowser/#/R-HSA-5244404 botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-HSA-5244428 https://reactome.org/PathwayBrowser/#/R-HSA-5244428 botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-HSA-5244506 https://reactome.org/PathwayBrowser/#/R-HSA-5244506 botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-HSA-5246514 https://reactome.org/PathwayBrowser/#/R-HSA-5246514 botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol TAS Homo sapiens 15378 R-HSA-5250616 https://reactome.org/PathwayBrowser/#/R-HSA-5250616 botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-HSA-5250884 https://reactome.org/PathwayBrowser/#/R-HSA-5250884 botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-HSA-5250972 https://reactome.org/PathwayBrowser/#/R-HSA-5250972 botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-HSA-5263614 https://reactome.org/PathwayBrowser/#/R-HSA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 TAS Homo sapiens 15378 R-HSA-5263616 https://reactome.org/PathwayBrowser/#/R-HSA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 TAS Homo sapiens 15378 R-HSA-5336420 https://reactome.org/PathwayBrowser/#/R-HSA-5336420 DT fragment B transports DT fragment A from target cell endosome membrane TAS Homo sapiens 15378 R-HSA-5340130 https://reactome.org/PathwayBrowser/#/R-HSA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol TAS Homo sapiens 15378 R-HSA-5340226 https://reactome.org/PathwayBrowser/#/R-HSA-5340226 CYGB dioxygenates NO TAS Homo sapiens 15378 R-HSA-5362518 https://reactome.org/PathwayBrowser/#/R-HSA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL TAS Homo sapiens 15378 R-HSA-5362522 https://reactome.org/PathwayBrowser/#/R-HSA-5362522 ALDHs oxidise atRAL to atRA TAS Homo sapiens 15378 R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 15378 R-HSA-5362564 https://reactome.org/PathwayBrowser/#/R-HSA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro TAS Homo sapiens 15378 R-HSA-5362721 https://reactome.org/PathwayBrowser/#/R-HSA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL TAS Homo sapiens 15378 R-HSA-5419165 https://reactome.org/PathwayBrowser/#/R-HSA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL TAS Homo sapiens 15378 R-HSA-5423637 https://reactome.org/PathwayBrowser/#/R-HSA-5423637 AKR dimers reduce AFBDHO to AFBDOH TAS Homo sapiens 15378 R-HSA-5423647 https://reactome.org/PathwayBrowser/#/R-HSA-5423647 CYP2A13 oxidises AFM1 to AFM1E TAS Homo sapiens 15378 R-HSA-5423664 https://reactome.org/PathwayBrowser/#/R-HSA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 TAS Homo sapiens 15378 R-HSA-5423672 https://reactome.org/PathwayBrowser/#/R-HSA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO TAS Homo sapiens 15378 R-HSA-5423678 https://reactome.org/PathwayBrowser/#/R-HSA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 TAS Homo sapiens 15378 R-HSA-548818 https://reactome.org/PathwayBrowser/#/R-HSA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA TAS Homo sapiens 15378 R-HSA-548831 https://reactome.org/PathwayBrowser/#/R-HSA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA TAS Homo sapiens 15378 R-HSA-5580269 https://reactome.org/PathwayBrowser/#/R-HSA-5580269 Defective CYP11A1 does not cleave 20a,22b-DHCHOL TAS Homo sapiens 15378 R-HSA-5580292 https://reactome.org/PathwayBrowser/#/R-HSA-5580292 Defective CYP11B1 does not oxidise 11DCORT TAS Homo sapiens 15378 R-HSA-5600598 https://reactome.org/PathwayBrowser/#/R-HSA-5600598 Defective CYP11B2 does not oxidise 11DCORST TAS Homo sapiens 15378 R-HSA-5601843 https://reactome.org/PathwayBrowser/#/R-HSA-5601843 Defective CYP17A1 does not 17-hydroxylate PREG TAS Homo sapiens 15378 R-HSA-5601849 https://reactome.org/PathwayBrowser/#/R-HSA-5601849 Defective CYP19A1 does not convert ANDST to E1 TAS Homo sapiens 15378 R-HSA-5601976 https://reactome.org/PathwayBrowser/#/R-HSA-5601976 Defective CYP21A2 does not 21-hydroxylate PROG TAS Homo sapiens 15378 R-HSA-5602004 https://reactome.org/PathwayBrowser/#/R-HSA-5602004 Defective CYP24A1 does not 24-hydroxylate CALTOL TAS Homo sapiens 15378 R-HSA-5602050 https://reactome.org/PathwayBrowser/#/R-HSA-5602050 Defective CYP26C1 does not 4-hydroxylate 9cRA TAS Homo sapiens 15378 R-HSA-5602063 https://reactome.org/PathwayBrowser/#/R-HSA-5602063 Defective CYP26B1 does not 4-hydroxylate atRA TAS Homo sapiens 15378 R-HSA-5602147 https://reactome.org/PathwayBrowser/#/R-HSA-5602147 Defective CYP2R1 does not 25-hydroxylate vitamin D TAS Homo sapiens 15378 R-HSA-5602170 https://reactome.org/PathwayBrowser/#/R-HSA-5602170 CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol TAS Homo sapiens 15378 R-HSA-5602186 https://reactome.org/PathwayBrowser/#/R-HSA-5602186 Defective CYP27B1 does not hydroxylate CDL TAS Homo sapiens 15378 R-HSA-5602242 https://reactome.org/PathwayBrowser/#/R-HSA-5602242 Defective CYP2U1 does not omega-hydroxylate ARA TAS Homo sapiens 15378 R-HSA-5602272 https://reactome.org/PathwayBrowser/#/R-HSA-5602272 Defective CYP4F22 does not 20-hydroxylate TrXA3 TAS Homo sapiens 15378 R-HSA-5602295 https://reactome.org/PathwayBrowser/#/R-HSA-5602295 CYP4F22 20-hydroxylates TrXA3 TAS Homo sapiens 15378 R-HSA-5602885 https://reactome.org/PathwayBrowser/#/R-HSA-5602885 Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL TAS Homo sapiens 15378 R-HSA-5602966 https://reactome.org/PathwayBrowser/#/R-HSA-5602966 Defective FMO3 does not N-oxidise TMA TAS Homo sapiens 15378 R-HSA-5605147 https://reactome.org/PathwayBrowser/#/R-HSA-5605147 Defective CYP1B1 does not 4-hydroxylate EST17b TAS Homo sapiens 15378 R-HSA-5615668 https://reactome.org/PathwayBrowser/#/R-HSA-5615668 AKR1C3 reduces atRAL to atROL TAS Homo sapiens 15378 R-HSA-5621402 https://reactome.org/PathwayBrowser/#/R-HSA-5621402 Defective CP does not oxidise Fe2+ to Fe3+ TAS Homo sapiens 15378 R-HSA-5623558 https://reactome.org/PathwayBrowser/#/R-HSA-5623558 Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-5623643 https://reactome.org/PathwayBrowser/#/R-HSA-5623643 RDH13 reduces atRAL to atROL TAS Homo sapiens 15378 R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-5624239 https://reactome.org/PathwayBrowser/#/R-HSA-5624239 Defective SLC17A5 does not cotransport Neu5Ac, H+ from lysosomal lumen to cytosol TAS Homo sapiens 15378 R-HSA-5624256 https://reactome.org/PathwayBrowser/#/R-HSA-5624256 Defective SLC17A8 does not exchange cytosolic L-Glu for synaptic vesicle H+ TAS Homo sapiens 15378 R-HSA-5625015 https://reactome.org/PathwayBrowser/#/R-HSA-5625015 Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-5625029 https://reactome.org/PathwayBrowser/#/R-HSA-5625029 SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-5625574 https://reactome.org/PathwayBrowser/#/R-HSA-5625574 Defective SLC22A18 does not exchange extracellular organic cations for cytosolic H+ TAS Homo sapiens 15378 R-HSA-5652172 https://reactome.org/PathwayBrowser/#/R-HSA-5652172 AKR1B1 reduces Glc to D-sorbitol TAS Homo sapiens 15378 R-HSA-5652195 https://reactome.org/PathwayBrowser/#/R-HSA-5652195 SORD oxidizes D-sorbitol to Fru TAS Homo sapiens 15378 R-HSA-5653850 https://reactome.org/PathwayBrowser/#/R-HSA-5653850 Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-5661039 https://reactome.org/PathwayBrowser/#/R-HSA-5661039 Defective SLC9A6 does not exchange Na+ for H+ across the early endosome membrane TAS Homo sapiens 15378 R-HSA-5661086 https://reactome.org/PathwayBrowser/#/R-HSA-5661086 Defective SLC9A9 does not exchange Na+ for H+ across the late endosome membrane TAS Homo sapiens 15378 R-HSA-5661240 https://reactome.org/PathwayBrowser/#/R-HSA-5661240 DCXR tetramer reduces L-xylulose to xylitol TAS Homo sapiens 15378 R-HSA-5661256 https://reactome.org/PathwayBrowser/#/R-HSA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate TAS Homo sapiens 15378 R-HSA-5661290 https://reactome.org/PathwayBrowser/#/R-HSA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate TAS Homo sapiens 15378 R-HSA-5662471 https://reactome.org/PathwayBrowser/#/R-HSA-5662471 SORD tetramer oxidizes xylitol to D-xylulose TAS Homo sapiens 15378 R-HSA-5662662 https://reactome.org/PathwayBrowser/#/R-HSA-5662662 Tyrosinase oxidises tyrosine to dopaquinone TAS Homo sapiens 15378 R-HSA-5662851 https://reactome.org/PathwayBrowser/#/R-HSA-5662851 Defective DCXR does not reduce L-xylulose to xylitol TAS Homo sapiens 15378 R-HSA-5668629 https://reactome.org/PathwayBrowser/#/R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP TAS Homo sapiens 15378 R-HSA-5668718 https://reactome.org/PathwayBrowser/#/R-HSA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15378 R-HSA-5668731 https://reactome.org/PathwayBrowser/#/R-HSA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15378 R-HSA-5678327 https://reactome.org/PathwayBrowser/#/R-HSA-5678327 MIOX oxidises Ins to GlcA TAS Homo sapiens 15378 R-HSA-5690565 https://reactome.org/PathwayBrowser/#/R-HSA-5690565 SCD desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15378 R-HSA-5691107 https://reactome.org/PathwayBrowser/#/R-HSA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) TAS Homo sapiens 15378 R-HSA-5692237 https://reactome.org/PathwayBrowser/#/R-HSA-5692237 ADH5 oxidises S-HMGSH to S-FGSH TAS Homo sapiens 15378 R-HSA-5692261 https://reactome.org/PathwayBrowser/#/R-HSA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM TAS Homo sapiens 15378 R-HSA-5692283 https://reactome.org/PathwayBrowser/#/R-HSA-5692283 ALD3A1 oxidises 4HPCP to CXPA TAS Homo sapiens 15378 R-HSA-5693347 https://reactome.org/PathwayBrowser/#/R-HSA-5693347 CRYM reduces P2C to PPCA TAS Homo sapiens 15378 R-HSA-5693390 https://reactome.org/PathwayBrowser/#/R-HSA-5693390 HSD17B11 dehydrogenates EST17b to E1 TAS Homo sapiens 15378 R-HSA-5693681 https://reactome.org/PathwayBrowser/#/R-HSA-5693681 DUOX1,2 reduce O2 to H2O2 TAS Homo sapiens 15378 R-HSA-5693691 https://reactome.org/PathwayBrowser/#/R-HSA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG TAS Homo sapiens 15378 R-HSA-5693761 https://reactome.org/PathwayBrowser/#/R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids TAS Homo sapiens 15378 R-HSA-5694018 https://reactome.org/PathwayBrowser/#/R-HSA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate TAS Homo sapiens 15378 R-HSA-5694462 https://reactome.org/PathwayBrowser/#/R-HSA-5694462 ABHD6,12 hydrolyse 3AG TAS Homo sapiens 15378 R-HSA-5696080 https://reactome.org/PathwayBrowser/#/R-HSA-5696080 ALDH3B1 oxidises HXAL to PALM TAS Homo sapiens 15378 R-HSA-5696091 https://reactome.org/PathwayBrowser/#/R-HSA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH TAS Homo sapiens 15378 R-HSA-5696101 https://reactome.org/PathwayBrowser/#/R-HSA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA TAS Homo sapiens 15378 R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 15378 R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 15378 R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 15378 R-HSA-5696457 https://reactome.org/PathwayBrowser/#/R-HSA-5696457 BDH2 dehydrogenates 3HBA TAS Homo sapiens 15378 R-HSA-5696822 https://reactome.org/PathwayBrowser/#/R-HSA-5696822 AKR1B15 reduces EST17b to E1 TAS Homo sapiens 15378 R-HSA-5696838 https://reactome.org/PathwayBrowser/#/R-HSA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS TAS Homo sapiens 15378 R-HSA-597628 https://reactome.org/PathwayBrowser/#/R-HSA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ TAS Homo sapiens 15378 R-HSA-6783221 https://reactome.org/PathwayBrowser/#/R-HSA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT TAS Homo sapiens 15378 R-HSA-6783939 https://reactome.org/PathwayBrowser/#/R-HSA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 15378 R-HSA-6783955 https://reactome.org/PathwayBrowser/#/R-HSA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 15378 R-HSA-6784399 https://reactome.org/PathwayBrowser/#/R-HSA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate TAS Homo sapiens 15378 R-HSA-6785244 https://reactome.org/PathwayBrowser/#/R-HSA-6785244 Defective CYP11B2 does not oxidise 18HCORST TAS Homo sapiens 15378 R-HSA-6785245 https://reactome.org/PathwayBrowser/#/R-HSA-6785245 Defective CYP11B2 does not oxidise CORST TAS Homo sapiens 15378 R-HSA-6785933 https://reactome.org/PathwayBrowser/#/R-HSA-6785933 UGT8 transfers Gal from UDP-Gal to CERA TAS Homo sapiens 15378 R-HSA-6786239 https://reactome.org/PathwayBrowser/#/R-HSA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE TAS Homo sapiens 15378 R-HSA-6786257 https://reactome.org/PathwayBrowser/#/R-HSA-6786257 DCTPP1 hydrolyses 5idCTP IEA Homo sapiens 15378 R-HSA-6786720 https://reactome.org/PathwayBrowser/#/R-HSA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA TAS Homo sapiens 15378 R-HSA-6787642 https://reactome.org/PathwayBrowser/#/R-HSA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc TAS Homo sapiens 15378 R-HSA-6788974 https://reactome.org/PathwayBrowser/#/R-HSA-6788974 Hypochlorous acid and nitrite react to nitryl chloride (NO2Cl) TAS Homo sapiens 15378 R-HSA-6788975 https://reactome.org/PathwayBrowser/#/R-HSA-6788975 Superoxide anion dismutates to H2O2 TAS Homo sapiens 15378 R-HSA-6788999 https://reactome.org/PathwayBrowser/#/R-HSA-6788999 HV1-mediated H+ transfer TAS Homo sapiens 15378 R-HSA-6789031 https://reactome.org/PathwayBrowser/#/R-HSA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 15378 R-HSA-6789092 https://reactome.org/PathwayBrowser/#/R-HSA-6789092 NOX2 generates superoxide anion from oxygen TAS Homo sapiens 15378 R-HSA-6789109 https://reactome.org/PathwayBrowser/#/R-HSA-6789109 Superoxide anion reacts with Fe-S cluster TAS Homo sapiens 15378 R-HSA-6789126 https://reactome.org/PathwayBrowser/#/R-HSA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 15378 R-HSA-6793590 https://reactome.org/PathwayBrowser/#/R-HSA-6793590 LIPT2 transfers octanoyl group to GCSH TAS Homo sapiens 15378 R-HSA-6793591 https://reactome.org/PathwayBrowser/#/R-HSA-6793591 LIAS synthesizes lipoyl-GCSH TAS Homo sapiens 15378 R-HSA-6798345 https://reactome.org/PathwayBrowser/#/R-HSA-6798345 PXLP-GCAT dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA TAS Homo sapiens 15378 R-HSA-6799495 https://reactome.org/PathwayBrowser/#/R-HSA-6799495 GLYCTK phosphorylates DGA to 3PDGA TAS Homo sapiens 15378 R-HSA-6799722 https://reactome.org/PathwayBrowser/#/R-HSA-6799722 TP53I3 oxidoreductase generates unstable semiquinones TAS Homo sapiens 15378 R-HSA-6801342 https://reactome.org/PathwayBrowser/#/R-HSA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG TAS Homo sapiens 15378 R-HSA-6803771 https://reactome.org/PathwayBrowser/#/R-HSA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P TAS Homo sapiens 15378 R-HSA-6803998 https://reactome.org/PathwayBrowser/#/R-HSA-6803998 Nitrite ion and HNO2 form a conjugated acid-base pair TAS Homo sapiens 15378 R-HSA-6806647 https://reactome.org/PathwayBrowser/#/R-HSA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 15378 R-HSA-6806831 https://reactome.org/PathwayBrowser/#/R-HSA-6806831 CYB5Rs reduce MetHb to HbA TAS Homo sapiens 15378 R-HSA-6806967 https://reactome.org/PathwayBrowser/#/R-HSA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH TAS Homo sapiens 15378 R-HSA-6807053 https://reactome.org/PathwayBrowser/#/R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL TAS Homo sapiens 15378 R-HSA-6807055 https://reactome.org/PathwayBrowser/#/R-HSA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL TAS Homo sapiens 15378 R-HSA-6807064 https://reactome.org/PathwayBrowser/#/R-HSA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL TAS Homo sapiens 15378 R-HSA-6807557 https://reactome.org/PathwayBrowser/#/R-HSA-6807557 NOX4, NOX5 reduce O2 to O2.- TAS Homo sapiens 15378 R-HSA-6807826 https://reactome.org/PathwayBrowser/#/R-HSA-6807826 LDHAL6B reduces PYR to LACT TAS Homo sapiens 15378 R-HSA-6808464 https://reactome.org/PathwayBrowser/#/R-HSA-6808464 ALDH3B2 oxidises HXAL to PALM TAS Homo sapiens 15378 R-HSA-6808487 https://reactome.org/PathwayBrowser/#/R-HSA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 15378 R-HSA-6808496 https://reactome.org/PathwayBrowser/#/R-HSA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 15378 R-HSA-6809264 https://reactome.org/PathwayBrowser/#/R-HSA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 15378 R-HSA-6809287 https://reactome.org/PathwayBrowser/#/R-HSA-6809287 NUDT12 hydrolyses NADH to NMNH TAS Homo sapiens 15378 R-HSA-6809810 https://reactome.org/PathwayBrowser/#/R-HSA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA TAS Homo sapiens 15378 R-HSA-6810594 https://reactome.org/PathwayBrowser/#/R-HSA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 15378 R-HSA-6813749 https://reactome.org/PathwayBrowser/#/R-HSA-6813749 ALDH1A1 oxidises GA to DGA TAS Homo sapiens 15378 R-HSA-6814153 https://reactome.org/PathwayBrowser/#/R-HSA-6814153 ADO oxidises 2AET to HTAU TAS Homo sapiens 15378 R-HSA-70333 https://reactome.org/PathwayBrowser/#/R-HSA-70333 KHK dimer phosphorylates Fru to Fru 1-P TAS Homo sapiens 15378 R-HSA-70377 https://reactome.org/PathwayBrowser/#/R-HSA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ TAS Homo sapiens 15378 R-HSA-70420 https://reactome.org/PathwayBrowser/#/R-HSA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P TAS Homo sapiens 15378 R-HSA-70449 https://reactome.org/PathwayBrowser/#/R-HSA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ TAS Homo sapiens 15378 R-HSA-70467 https://reactome.org/PathwayBrowser/#/R-HSA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP TAS Homo sapiens 15378 R-HSA-70482 https://reactome.org/PathwayBrowser/#/R-HSA-70482 GAPDH tetramers reduce 1,3BPG to GA3P TAS Homo sapiens 15378 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 15378 R-HSA-70510 https://reactome.org/PathwayBrowser/#/R-HSA-70510 LDH tetramer oxidises LACT to PYR TAS Homo sapiens 15378 R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] TAS Homo sapiens 15378 R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] TAS Homo sapiens 15378 R-HSA-70664 https://reactome.org/PathwayBrowser/#/R-HSA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 15378 R-HSA-70670 https://reactome.org/PathwayBrowser/#/R-HSA-70670 PRODH oxidises L-Pro to 1PYR-5COOH TAS Homo sapiens 15378 R-HSA-70679 https://reactome.org/PathwayBrowser/#/R-HSA-70679 ALDH4A1 oxidises L-GluSS to Glu TAS Homo sapiens 15378 R-HSA-70837 https://reactome.org/PathwayBrowser/#/R-HSA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ TAS Homo sapiens 15378 R-HSA-70885 https://reactome.org/PathwayBrowser/#/R-HSA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ TAS Homo sapiens 15378 R-HSA-70893 https://reactome.org/PathwayBrowser/#/R-HSA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ TAS Homo sapiens 15378 R-HSA-70906 https://reactome.org/PathwayBrowser/#/R-HSA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ TAS Homo sapiens 15378 R-HSA-70938 https://reactome.org/PathwayBrowser/#/R-HSA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O TAS Homo sapiens 15378 R-HSA-70940 https://reactome.org/PathwayBrowser/#/R-HSA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ TAS Homo sapiens 15378 R-HSA-70941 https://reactome.org/PathwayBrowser/#/R-HSA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ TAS Homo sapiens 15378 R-HSA-70975 https://reactome.org/PathwayBrowser/#/R-HSA-70975 CS acetylates OA to citrate TAS Homo sapiens 15378 R-HSA-70979 https://reactome.org/PathwayBrowser/#/R-HSA-70979 MDH2 dimer dehydrogenates MAL TAS Homo sapiens 15378 R-HSA-71130 https://reactome.org/PathwayBrowser/#/R-HSA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ TAS Homo sapiens 15378 R-HSA-71164 https://reactome.org/PathwayBrowser/#/R-HSA-71164 HGD dioxygenates homogentisate TAS Homo sapiens 15378 R-HSA-71181 https://reactome.org/PathwayBrowser/#/R-HSA-71181 FAH cleaves 4FAA TAS Homo sapiens 15378 R-HSA-71200 https://reactome.org/PathwayBrowser/#/R-HSA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O TAS Homo sapiens 15378 R-HSA-71239 https://reactome.org/PathwayBrowser/#/R-HSA-71239 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ IEA Homo sapiens 15378 R-HSA-71260 https://reactome.org/PathwayBrowser/#/R-HSA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT TAS Homo sapiens 15378 R-HSA-71286 https://reactome.org/PathwayBrowser/#/R-HSA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine TAS Homo sapiens 15378 R-HSA-71299 https://reactome.org/PathwayBrowser/#/R-HSA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ TAS Homo sapiens 15378 R-HSA-71401 https://reactome.org/PathwayBrowser/#/R-HSA-71401 OGDH dimer decarboxylates 2-OG TAS Homo sapiens 15378 R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 15378 R-HSA-71682 https://reactome.org/PathwayBrowser/#/R-HSA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 15378 R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 15378 R-HSA-71707 https://reactome.org/PathwayBrowser/#/R-HSA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ TAS Homo sapiens 15378 R-HSA-71723 https://reactome.org/PathwayBrowser/#/R-HSA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] TAS Homo sapiens 15378 R-HSA-71849 https://reactome.org/PathwayBrowser/#/R-HSA-71849 LDH tetramer reduces PYR to LACT TAS Homo sapiens 15378 R-HSA-73564 https://reactome.org/PathwayBrowser/#/R-HSA-73564 UMPS dimer decarboxylates OMP to UMP TAS Homo sapiens 15378 R-HSA-73571 https://reactome.org/PathwayBrowser/#/R-HSA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO TAS Homo sapiens 15378 R-HSA-73573 https://reactome.org/PathwayBrowser/#/R-HSA-73573 CAD hexamer transforms CAP to N-carb-L-Asp TAS Homo sapiens 15378 R-HSA-73577 https://reactome.org/PathwayBrowser/#/R-HSA-73577 CAD hexamer transforms L-Gln to CAP TAS Homo sapiens 15378 R-HSA-73585 https://reactome.org/PathwayBrowser/#/R-HSA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ TAS Homo sapiens 15378 R-HSA-73589 https://reactome.org/PathwayBrowser/#/R-HSA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate TAS Homo sapiens 15378 R-HSA-73591 https://reactome.org/PathwayBrowser/#/R-HSA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 TAS Homo sapiens 15378 R-HSA-73596 https://reactome.org/PathwayBrowser/#/R-HSA-73596 dCMP + H2O => dUMP + NH4+ TAS Homo sapiens 15378 R-HSA-73616 https://reactome.org/PathwayBrowser/#/R-HSA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ TAS Homo sapiens 15378 R-HSA-73618 https://reactome.org/PathwayBrowser/#/R-HSA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate TAS Homo sapiens 15378 R-HSA-73620 https://reactome.org/PathwayBrowser/#/R-HSA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 TAS Homo sapiens 15378 R-HSA-73646 https://reactome.org/PathwayBrowser/#/R-HSA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ TAS Homo sapiens 15378 R-HSA-73647 https://reactome.org/PathwayBrowser/#/R-HSA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] TAS Homo sapiens 15378 R-HSA-73666 https://reactome.org/PathwayBrowser/#/R-HSA-73666 dUTP + H2O => dUMP + pyrophosphate TAS Homo sapiens 15378 R-HSA-73792 https://reactome.org/PathwayBrowser/#/R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate TAS Homo sapiens 15378 R-HSA-73794 https://reactome.org/PathwayBrowser/#/R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] TAS Homo sapiens 15378 R-HSA-73805 https://reactome.org/PathwayBrowser/#/R-HSA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi TAS Homo sapiens 15378 R-HSA-73806 https://reactome.org/PathwayBrowser/#/R-HSA-73806 AIR + CO2 => CAIR TAS Homo sapiens 15378 R-HSA-73810 https://reactome.org/PathwayBrowser/#/R-HSA-73810 FGAM + ATP => AIR + ADP + Pi TAS Homo sapiens 15378 R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 15378 R-HSA-73813 https://reactome.org/PathwayBrowser/#/R-HSA-73813 GAR + 10-Formyl-THF => FGAR + THF TAS Homo sapiens 15378 R-HSA-73814 https://reactome.org/PathwayBrowser/#/R-HSA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi TAS Homo sapiens 15378 R-HSA-73912 https://reactome.org/PathwayBrowser/#/R-HSA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ TAS Homo sapiens 15378 R-HSA-73920 https://reactome.org/PathwayBrowser/#/R-HSA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ TAS Homo sapiens 15378 R-HSA-74255 https://reactome.org/PathwayBrowser/#/R-HSA-74255 Guanine + H2O => Xanthine + NH4+ TAS Homo sapiens 15378 R-HSA-74723 https://reactome.org/PathwayBrowser/#/R-HSA-74723 Endosome acidification TAS Homo sapiens 15378 R-HSA-74872 https://reactome.org/PathwayBrowser/#/R-HSA-74872 RDH10,11 oxidise 11cROL to 11cRAL TAS Homo sapiens 15378 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15378 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15378 R-HSA-75872 https://reactome.org/PathwayBrowser/#/R-HSA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O TAS Homo sapiens 15378 R-HSA-75883 https://reactome.org/PathwayBrowser/#/R-HSA-75883 DHRS7B reduces GO3P to HXDG3P TAS Homo sapiens 15378 R-HSA-75889 https://reactome.org/PathwayBrowser/#/R-HSA-75889 DHAP is converted to G3P by GPD1/GPD1L TAS Homo sapiens 15378 R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 15378 R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 15378 R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 15378 R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 15378 R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 15378 R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 15378 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 15378 R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 15378 R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 15378 R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 15378 R-HSA-77254 https://reactome.org/PathwayBrowser/#/R-HSA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H TAS Homo sapiens 15378 R-HSA-77283 https://reactome.org/PathwayBrowser/#/R-HSA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H TAS Homo sapiens 15378 R-HSA-77303 https://reactome.org/PathwayBrowser/#/R-HSA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H TAS Homo sapiens 15378 R-HSA-77312 https://reactome.org/PathwayBrowser/#/R-HSA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H TAS Homo sapiens 15378 R-HSA-77323 https://reactome.org/PathwayBrowser/#/R-HSA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H TAS Homo sapiens 15378 R-HSA-77331 https://reactome.org/PathwayBrowser/#/R-HSA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H TAS Homo sapiens 15378 R-HSA-77342 https://reactome.org/PathwayBrowser/#/R-HSA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H TAS Homo sapiens 15378 R-HSA-804969 https://reactome.org/PathwayBrowser/#/R-HSA-804969 HSD17B1 hydrogenates E1 to EST17b TAS Homo sapiens 15378 R-HSA-880053 https://reactome.org/PathwayBrowser/#/R-HSA-880053 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] TAS Homo sapiens 15378 R-HSA-8847579 https://reactome.org/PathwayBrowser/#/R-HSA-8847579 SCD5 desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15378 R-HSA-8849638 https://reactome.org/PathwayBrowser/#/R-HSA-8849638 Dissociation of the SPINK5:KLK5 complex at low pH TAS Homo sapiens 15378 R-HSA-8850846 https://reactome.org/PathwayBrowser/#/R-HSA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-HSA-8850854 https://reactome.org/PathwayBrowser/#/R-HSA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-HSA-8851110 https://reactome.org/PathwayBrowser/#/R-HSA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-HSA-8851129 https://reactome.org/PathwayBrowser/#/R-HSA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 15378 R-HSA-8862137 https://reactome.org/PathwayBrowser/#/R-HSA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 15378 R-HSA-8862152 https://reactome.org/PathwayBrowser/#/R-HSA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP TAS Homo sapiens 15378 R-HSA-8863494 https://reactome.org/PathwayBrowser/#/R-HSA-8863494 ASICs bind STOML3, (STOM) TAS Homo sapiens 15378 R-HSA-8866601 https://reactome.org/PathwayBrowser/#/R-HSA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate TAS Homo sapiens 15378 R-HSA-8869606 https://reactome.org/PathwayBrowser/#/R-HSA-8869606 NMRK1 phosphorylates NAR to yield NAMN TAS Homo sapiens 15378 R-HSA-8869607 https://reactome.org/PathwayBrowser/#/R-HSA-8869607 NMRK2 phosphorylates NAR to yield NAMN TAS Homo sapiens 15378 R-HSA-8869627 https://reactome.org/PathwayBrowser/#/R-HSA-8869627 NMRK2 phosphorylates NR to yield NMN TAS Homo sapiens 15378 R-HSA-8869633 https://reactome.org/PathwayBrowser/#/R-HSA-8869633 NMRK1 phosphorylates NR to yield NMN TAS Homo sapiens 15378 R-HSA-8870346 https://reactome.org/PathwayBrowser/#/R-HSA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose TAS Homo sapiens 15378 R-HSA-8875623 https://reactome.org/PathwayBrowser/#/R-HSA-8875623 SLC25A18,22 import L-Glu, H+ TAS Homo sapiens 15378 R-HSA-8878914 https://reactome.org/PathwayBrowser/#/R-HSA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer TAS Homo sapiens 15378 R-HSA-888548 https://reactome.org/PathwayBrowser/#/R-HSA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA TAS Homo sapiens 15378 R-HSA-888572 https://reactome.org/PathwayBrowser/#/R-HSA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA TAS Homo sapiens 15378 R-HSA-888577 https://reactome.org/PathwayBrowser/#/R-HSA-888577 Synthesis of GABA by GAD2 TAS Homo sapiens 15378 R-HSA-8933635 https://reactome.org/PathwayBrowser/#/R-HSA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide TAS Homo sapiens 15378 R-HSA-8936442 https://reactome.org/PathwayBrowser/#/R-HSA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds TAS Homo sapiens 15378 R-HSA-8938076 https://reactome.org/PathwayBrowser/#/R-HSA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose TAS Homo sapiens 15378 R-HSA-8949687 https://reactome.org/PathwayBrowser/#/R-HSA-8949687 LETM1 exchanges protons (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Homo sapiens 15378 R-HSA-8952873 https://reactome.org/PathwayBrowser/#/R-HSA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA TAS Homo sapiens 15378 R-HSA-8954468 https://reactome.org/PathwayBrowser/#/R-HSA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA TAS Homo sapiens 15378 R-HSA-8955030 https://reactome.org/PathwayBrowser/#/R-HSA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ TAS Homo sapiens 15378 R-HSA-8955760 https://reactome.org/PathwayBrowser/#/R-HSA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP TAS Homo sapiens 15378 R-HSA-8956427 https://reactome.org/PathwayBrowser/#/R-HSA-8956427 RETSAT reduces atROL to at-13,14-dhROL IEA Homo sapiens 15378 R-HSA-8956458 https://reactome.org/PathwayBrowser/#/R-HSA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ TAS Homo sapiens 15378 R-HSA-8959510 https://reactome.org/PathwayBrowser/#/R-HSA-8959510 SEPHS2 phosphorylates H2Se to form SELP TAS Homo sapiens 15378 R-HSA-8959719 https://reactome.org/PathwayBrowser/#/R-HSA-8959719 SHPK phosphorylates Sedo to Sedo7P TAS Homo sapiens 15378 R-HSA-9009950 https://reactome.org/PathwayBrowser/#/R-HSA-9009950 PDE12 cleaves 2'-5' oligoadenylates TAS Homo sapiens 15378 R-HSA-9011595 https://reactome.org/PathwayBrowser/#/R-HSA-9011595 GSTZ1 dimer dehalogenates DCA TAS Homo sapiens 15378 R-HSA-9012016 https://reactome.org/PathwayBrowser/#/R-HSA-9012016 FAHD1 dimer hydrolyses OA to PYR TAS Homo sapiens 15378 R-HSA-9012036 https://reactome.org/PathwayBrowser/#/R-HSA-9012036 ME1 tetramer decarboxylates MAL to PYR TAS Homo sapiens 15378 R-HSA-9018874 https://reactome.org/PathwayBrowser/#/R-HSA-9018874 CYP monooxygenates EPA to 18(S)-HpEPE TAS Homo sapiens 15378 R-HSA-9024993 https://reactome.org/PathwayBrowser/#/R-HSA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 TAS Homo sapiens 15378 R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 15378 R-HSA-9027043 https://reactome.org/PathwayBrowser/#/R-HSA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA TAS Homo sapiens 15378 R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 15378 R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 15378 R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 15378 R-HSA-9027625 https://reactome.org/PathwayBrowser/#/R-HSA-9027625 5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3 TAS Homo sapiens 15378 R-HSA-9027631 https://reactome.org/PathwayBrowser/#/R-HSA-9027631 5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA TAS Homo sapiens 15378 R-HSA-9027632 https://reactome.org/PathwayBrowser/#/R-HSA-9027632 5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA TAS Homo sapiens 15378 R-HSA-9035954 https://reactome.org/PathwayBrowser/#/R-HSA-9035954 Defective CYP17A1 does not 17-hydroxylate P4 TAS Homo sapiens 15378 R-HSA-9035956 https://reactome.org/PathwayBrowser/#/R-HSA-9035956 Defective CYP17A1 does not cleave 17aHPROG TAS Homo sapiens 15378 R-HSA-9035960 https://reactome.org/PathwayBrowser/#/R-HSA-9035960 Defective CYP27A1 does not 27-hydroxylate 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 15378 R-HSA-9037761 https://reactome.org/PathwayBrowser/#/R-HSA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 TAS Homo sapiens 15378 R-HSA-917811 https://reactome.org/PathwayBrowser/#/R-HSA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ TAS Homo sapiens 15378 R-HSA-917841 https://reactome.org/PathwayBrowser/#/R-HSA-917841 Acidification of Tf:TfR1 containing endosome TAS Homo sapiens 15378 R-HSA-917891 https://reactome.org/PathwayBrowser/#/R-HSA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ TAS Homo sapiens 15378 R-HSA-917933 https://reactome.org/PathwayBrowser/#/R-HSA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ TAS Homo sapiens 15378 R-HSA-917979 https://reactome.org/PathwayBrowser/#/R-HSA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region TAS Homo sapiens 15378 R-HSA-937311 https://reactome.org/PathwayBrowser/#/R-HSA-937311 ATP12A:ATP4B exchanges K+ for H+ TAS Homo sapiens 15378 R-HSA-947541 https://reactome.org/PathwayBrowser/#/R-HSA-947541 Sulfhydrylation and ring cleavage of precursor Z TAS Homo sapiens 15378 R-HSA-9615042 https://reactome.org/PathwayBrowser/#/R-HSA-9615042 Viral 2',5'-PDE cleaves 2'-5' oligoadenylates TAS Homo sapiens 15378 R-HSA-9620103 https://reactome.org/PathwayBrowser/#/R-HSA-9620103 ALDH2 transforms GTN to NO TAS Homo sapiens 15378 R-HSA-9625540 https://reactome.org/PathwayBrowser/#/R-HSA-9625540 Cys-sulfenyl chloride is converted to Cys-sulfenic acid TAS Homo sapiens 15378 R-HSA-9636560 https://reactome.org/PathwayBrowser/#/R-HSA-9636560 Eis acetylates DUSP16 TAS Homo sapiens 15378 R-HSA-9637699 https://reactome.org/PathwayBrowser/#/R-HSA-9637699 CpnT hydrolyses NAD+ TAS Homo sapiens 15378 R-HSA-9640302 https://reactome.org/PathwayBrowser/#/R-HSA-9640302 Asc.- radical dissociates to AscH- and DeHA TAS Homo sapiens 15378 R-HSA-9640321 https://reactome.org/PathwayBrowser/#/R-HSA-9640321 2,3-DKG hydrolyses to ERU and oxalate TAS Homo sapiens 15378 R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-HSA-9650165 https://reactome.org/PathwayBrowser/#/R-HSA-9650165 ASIC trimers bind H+ TAS Homo sapiens 15378 R-HSA-9668415 https://reactome.org/PathwayBrowser/#/R-HSA-9668415 VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope TAS Homo sapiens 15378 R-HSA-9673797 https://reactome.org/PathwayBrowser/#/R-HSA-9673797 NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15378 R-HSA-9683467 https://reactome.org/PathwayBrowser/#/R-HSA-9683467 CQ, HCQ are protonated to CQ2+, HCQ2+ TAS Homo sapiens 15378 R-HSA-9683648 https://reactome.org/PathwayBrowser/#/R-HSA-9683648 Spike trimer glycoside chains are extended TAS Homo sapiens 15378 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 15378 R-HSA-9683669 https://reactome.org/PathwayBrowser/#/R-HSA-9683669 E protein gets N-glycosylated TAS Homo sapiens 15378 R-HSA-9683751 https://reactome.org/PathwayBrowser/#/R-HSA-9683751 M protein gets N-glycosylated TAS Homo sapiens 15378 R-HSA-9683755 https://reactome.org/PathwayBrowser/#/R-HSA-9683755 Spike protein gets N-glycosylated TAS Homo sapiens 15378 R-HSA-9683760 https://reactome.org/PathwayBrowser/#/R-HSA-9683760 GalNAc is transferred onto 3a TAS Homo sapiens 15378 R-HSA-9684261 https://reactome.org/PathwayBrowser/#/R-HSA-9684261 nsp4 is glycosylated TAS Homo sapiens 15378 R-HSA-9684275 https://reactome.org/PathwayBrowser/#/R-HSA-9684275 nsp3-4 is glycosylated TAS Homo sapiens 15378 R-HSA-9684290 https://reactome.org/PathwayBrowser/#/R-HSA-9684290 nsp3 is glycosylated TAS Homo sapiens 15378 R-HSA-9686061 https://reactome.org/PathwayBrowser/#/R-HSA-9686061 Nucleoprotein is ADP-ribosylated TAS Homo sapiens 15378 R-HSA-9694331 https://reactome.org/PathwayBrowser/#/R-HSA-9694331 nsp3-4 is glycosylated IEA Homo sapiens 15378 R-HSA-9694389 https://reactome.org/PathwayBrowser/#/R-HSA-9694389 nsp3 is glycosylated IEA Homo sapiens 15378 R-HSA-9694438 https://reactome.org/PathwayBrowser/#/R-HSA-9694438 GalNAc is transferred onto 3a IEA Homo sapiens 15378 R-HSA-9694525 https://reactome.org/PathwayBrowser/#/R-HSA-9694525 M protein gets N-glycosylated IEA Homo sapiens 15378 R-HSA-9694611 https://reactome.org/PathwayBrowser/#/R-HSA-9694611 nsp4 is glycosylated IEA Homo sapiens 15378 R-HSA-9694790 https://reactome.org/PathwayBrowser/#/R-HSA-9694790 E protein gets N-glycosylated IEA Homo sapiens 15378 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 15378 R-HSA-9698758 https://reactome.org/PathwayBrowser/#/R-HSA-9698758 FLT3 ITD- and NOX4-dependent H2O2 production TAS Homo sapiens 15378 R-HSA-9705713 https://reactome.org/PathwayBrowser/#/R-HSA-9705713 SRD5A2 dehydrogenates TEST to DHTEST TAS Homo sapiens 15378 R-HSA-9705714 https://reactome.org/PathwayBrowser/#/R-HSA-9705714 SRD5A3 dehydrogenates TEST to DHTEST TAS Homo sapiens 15378 R-HSA-9709098 https://reactome.org/PathwayBrowser/#/R-HSA-9709098 DHFR dimer reduces FOLA to DHF TAS Homo sapiens 15378 R-HSA-9727198 https://reactome.org/PathwayBrowser/#/R-HSA-9727198 ATP4A:ATP4B exchanges K+ for H+ TAS Homo sapiens 15378 R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 15378 R-HSA-9727349 https://reactome.org/PathwayBrowser/#/R-HSA-9727349 XDH dehydrogenates xanthine to form urate TAS Homo sapiens 15378 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 15378 R-HSA-9729279 https://reactome.org/PathwayBrowser/#/R-HSA-9729279 Nucleoprotein is ADP-ribosylated IEA Homo sapiens 15378 R-HSA-9729283 https://reactome.org/PathwayBrowser/#/R-HSA-9729283 Nucleoprotein is methylated by PRMT1 TAS Homo sapiens 15378 R-HSA-9729300 https://reactome.org/PathwayBrowser/#/R-HSA-9729300 Unknown kinase phosphorylates nucleoprotein TAS Homo sapiens 15378 R-HSA-9729318 https://reactome.org/PathwayBrowser/#/R-HSA-9729318 CSNK1A1 phosphorylates nucleoprotein TAS Homo sapiens 15378 R-HSA-9729330 https://reactome.org/PathwayBrowser/#/R-HSA-9729330 SRPK1/2 phosphorylates nucleoprotein TAS Homo sapiens 15378 R-HSA-9729542 https://reactome.org/PathwayBrowser/#/R-HSA-9729542 OTOP1 transports H+ from the extracellular region to the cytosol IEA Homo sapiens 15378 R-HSA-9729870 https://reactome.org/PathwayBrowser/#/R-HSA-9729870 KCNJ2 (KIR2.1) transports K+ from the extracellular region to the cytosol IEA Homo sapiens 15378 R-HSA-9731228 https://reactome.org/PathwayBrowser/#/R-HSA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP TAS Homo sapiens 15378 R-HSA-9731590 https://reactome.org/PathwayBrowser/#/R-HSA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP TAS Homo sapiens 15378 R-HSA-9731613 https://reactome.org/PathwayBrowser/#/R-HSA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP TAS Homo sapiens 15378 R-HSA-9731632 https://reactome.org/PathwayBrowser/#/R-HSA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP TAS Homo sapiens 15378 R-HSA-9731661 https://reactome.org/PathwayBrowser/#/R-HSA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine TAS Homo sapiens 15378 R-HSA-9748945 https://reactome.org/PathwayBrowser/#/R-HSA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP TAS Homo sapiens 15378 R-HSA-9748957 https://reactome.org/PathwayBrowser/#/R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP TAS Homo sapiens 15378 R-HSA-9748979 https://reactome.org/PathwayBrowser/#/R-HSA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP TAS Homo sapiens 15378 R-HSA-9748983 https://reactome.org/PathwayBrowser/#/R-HSA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP TAS Homo sapiens 15378 R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 15378 R-HSA-9749609 https://reactome.org/PathwayBrowser/#/R-HSA-9749609 BCHE hydrolyzes ASA- TAS Homo sapiens 15378 R-HSA-9749647 https://reactome.org/PathwayBrowser/#/R-HSA-9749647 CES2 hydrolyzes ASA- TAS Homo sapiens 15378 R-HSA-9749792 https://reactome.org/PathwayBrowser/#/R-HSA-9749792 CES1,CES2 hydrolyze ASA- to ST TAS Homo sapiens 15378 R-HSA-9753285 https://reactome.org/PathwayBrowser/#/R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI TAS Homo sapiens 15378 R-HSA-9755937 https://reactome.org/PathwayBrowser/#/R-HSA-9755937 DHCR24 reduces LAN to 24,25-dhLAN TAS Homo sapiens 15378 R-HSA-9756134 https://reactome.org/PathwayBrowser/#/R-HSA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL TAS Homo sapiens 15378 R-HSA-9756136 https://reactome.org/PathwayBrowser/#/R-HSA-9756136 PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV IEA Homo sapiens 15378 R-HSA-9756138 https://reactome.org/PathwayBrowser/#/R-HSA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL TAS Homo sapiens 15378 R-HSA-9756150 https://reactome.org/PathwayBrowser/#/R-HSA-9756150 PON1,3 hydrolyse 4-OH-ATVL to 4-OH-ATV IEA Homo sapiens 15378 R-HSA-9756156 https://reactome.org/PathwayBrowser/#/R-HSA-9756156 UGT1A3 lactonizes ATV to ATVL TAS Homo sapiens 15378 R-HSA-9756162 https://reactome.org/PathwayBrowser/#/R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV TAS Homo sapiens 15378 R-HSA-9756169 https://reactome.org/PathwayBrowser/#/R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV TAS Homo sapiens 15378 R-HSA-9756177 https://reactome.org/PathwayBrowser/#/R-HSA-9756177 PON1,3 hydrolyse ATVL to ATV TAS Homo sapiens 15378 R-HSA-9756180 https://reactome.org/PathwayBrowser/#/R-HSA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL TAS Homo sapiens 15378 R-HSA-9756183 https://reactome.org/PathwayBrowser/#/R-HSA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL TAS Homo sapiens 15378 R-HSA-975629 https://reactome.org/PathwayBrowser/#/R-HSA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL TAS Homo sapiens 15378 R-HSA-9757434 https://reactome.org/PathwayBrowser/#/R-HSA-9757434 Acetylsalicylic acid dissolves TAS Homo sapiens 15378 R-HSA-9757706 https://reactome.org/PathwayBrowser/#/R-HSA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell TAS Homo sapiens 15378 R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 15378 R-HSA-9758674 https://reactome.org/PathwayBrowser/#/R-HSA-9758674 CYP3A4 oxidizes PREDN,PREDL TAS Homo sapiens 15378 R-HSA-9758682 https://reactome.org/PathwayBrowser/#/R-HSA-9758682 AKR1C1 hydrogenates PREDN,PREDL TAS Homo sapiens 15378 R-HSA-9759259 https://reactome.org/PathwayBrowser/#/R-HSA-9759259 HSD11B2 dehydrogenates PREDL to PREDN TAS Homo sapiens 15378 R-HSA-9759549 https://reactome.org/PathwayBrowser/#/R-HSA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin TAS Homo sapiens 15378 R-HSA-9760094 https://reactome.org/PathwayBrowser/#/R-HSA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer TAS Homo sapiens 15378 R-HSA-977348 https://reactome.org/PathwayBrowser/#/R-HSA-977348 PHGDH tetramer dehydrogenates 3PG TAS Homo sapiens 15378 R-HSA-9793628 https://reactome.org/PathwayBrowser/#/R-HSA-9793628 Cipro is imported by organic cation transporters TAS Homo sapiens 15378 R-HSA-9794270 https://reactome.org/PathwayBrowser/#/R-HSA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol TAS Homo sapiens 15378 R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 15378 R-HSA-9817513 https://reactome.org/PathwayBrowser/#/R-HSA-9817513 AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine IEA Homo sapiens 15378 R-HSA-9822583 https://reactome.org/PathwayBrowser/#/R-HSA-9822583 METTL23 dimethylates histone H3.3 arginine-17 (arginine-18 in the preprotein) IEA Homo sapiens 15378 R-HSA-9837337 https://reactome.org/PathwayBrowser/#/R-HSA-9837337 DCAKD phosphorylates DP-CoA TAS Homo sapiens 15378 R-HSA-9837354 https://reactome.org/PathwayBrowser/#/R-HSA-9837354 NUDT8 hydrolyzes CoA-SH to PPANT IEA Homo sapiens 15378 R-HSA-9843721 https://reactome.org/PathwayBrowser/#/R-HSA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region TAS Homo sapiens 15378 R-HSA-9844587 https://reactome.org/PathwayBrowser/#/R-HSA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer TAS Homo sapiens 15378 R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 15378 R-HSA-9845516 https://reactome.org/PathwayBrowser/#/R-HSA-9845516 B3GALT4 transfers Gal to gangliosides TAS Homo sapiens 15378 R-HSA-9845538 https://reactome.org/PathwayBrowser/#/R-HSA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides TAS Homo sapiens 15378 R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 15378 R-HSA-9846305 https://reactome.org/PathwayBrowser/#/R-HSA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b TAS Homo sapiens 15378 R-HSA-9846332 https://reactome.org/PathwayBrowser/#/R-HSA-9846332 FUT1,2 transfer fucose to gangliosides TAS Homo sapiens 15378 R-HSA-9846477 https://reactome.org/PathwayBrowser/#/R-HSA-9846477 A4GALT transfers galactose to LacCer TAS Homo sapiens 15378 R-HSA-9846501 https://reactome.org/PathwayBrowser/#/R-HSA-9846501 B3GNT5 transfers GlcNAc to LacCer TAS Homo sapiens 15378 R-HSA-9851347 https://reactome.org/PathwayBrowser/#/R-HSA-9851347 B4GALT5/6 transfer Gal to GlcCer TAS Homo sapiens 15378 R-HSA-9853499 https://reactome.org/PathwayBrowser/#/R-HSA-9853499 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 15378 R-HSA-9854315 https://reactome.org/PathwayBrowser/#/R-HSA-9854315 CSKMT methylates Citrate Synthase TAS Homo sapiens 15378 R-HSA-9854415 https://reactome.org/PathwayBrowser/#/R-HSA-9854415 ACAT1 tetramer acetylates IDH2 dimer TAS Homo sapiens 15378 R-HSA-9856871 https://reactome.org/PathwayBrowser/#/R-HSA-9856871 MDH1 reduces OA TAS Homo sapiens 15378 R-HSA-9861616 https://reactome.org/PathwayBrowser/#/R-HSA-9861616 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 15378 R-HSA-9861642 https://reactome.org/PathwayBrowser/#/R-HSA-9861642 NEK1 phosphorylates ME1 TAS Homo sapiens 15378 R-HSA-9861660 https://reactome.org/PathwayBrowser/#/R-HSA-9861660 ME1 tetramer decarboxylates OA to PYR TAS Homo sapiens 15378 R-HSA-9861734 https://reactome.org/PathwayBrowser/#/R-HSA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT TAS Homo sapiens 15378 R-HSA-9863531 https://reactome.org/PathwayBrowser/#/R-HSA-9863531 GS-MCA spontaneously hydrolyzes TAS Homo sapiens 15378 R-MMU-109343 https://reactome.org/PathwayBrowser/#/R-MMU-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Mus musculus 15378 R-MMU-111524 https://reactome.org/PathwayBrowser/#/R-MMU-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Mus musculus 15378 R-MMU-1222376 https://reactome.org/PathwayBrowser/#/R-MMU-1222376 NOX2 generates superoxide from oxygen IEA Mus musculus 15378 R-MMU-1222516 https://reactome.org/PathwayBrowser/#/R-MMU-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Mus musculus 15378 R-MMU-1236967 https://reactome.org/PathwayBrowser/#/R-MMU-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Mus musculus 15378 R-MMU-1237045 https://reactome.org/PathwayBrowser/#/R-MMU-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Mus musculus 15378 R-MMU-1237047 https://reactome.org/PathwayBrowser/#/R-MMU-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Mus musculus 15378 R-MMU-1237059 https://reactome.org/PathwayBrowser/#/R-MMU-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Mus musculus 15378 R-MMU-1237081 https://reactome.org/PathwayBrowser/#/R-MMU-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Mus musculus 15378 R-MMU-1237129 https://reactome.org/PathwayBrowser/#/R-MMU-1237129 Acireductone is created IEA Mus musculus 15378 R-MMU-1237325 https://reactome.org/PathwayBrowser/#/R-MMU-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Mus musculus 15378 R-MMU-1247668 https://reactome.org/PathwayBrowser/#/R-MMU-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Mus musculus 15378 R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 15378 R-MMU-140359 https://reactome.org/PathwayBrowser/#/R-MMU-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Mus musculus 15378 R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 15378 R-MMU-1475017 https://reactome.org/PathwayBrowser/#/R-MMU-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Mus musculus 15378 R-MMU-1475022 https://reactome.org/PathwayBrowser/#/R-MMU-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Mus musculus 15378 R-MMU-1475025 https://reactome.org/PathwayBrowser/#/R-MMU-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Mus musculus 15378 R-MMU-1475026 https://reactome.org/PathwayBrowser/#/R-MMU-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Mus musculus 15378 R-MMU-1475028 https://reactome.org/PathwayBrowser/#/R-MMU-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Mus musculus 15378 R-MMU-1475032 https://reactome.org/PathwayBrowser/#/R-MMU-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Mus musculus 15378 R-MMU-1475435 https://reactome.org/PathwayBrowser/#/R-MMU-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Mus musculus 15378 R-MMU-1475436 https://reactome.org/PathwayBrowser/#/R-MMU-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Mus musculus 15378 R-MMU-1497770 https://reactome.org/PathwayBrowser/#/R-MMU-1497770 Salvage - BH2 is reduced to BH4 by Dhfr TAS Mus musculus 15378 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 15378 R-MMU-1497869 https://reactome.org/PathwayBrowser/#/R-MMU-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Mus musculus 15378 R-MMU-1562626 https://reactome.org/PathwayBrowser/#/R-MMU-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Mus musculus 15378 R-MMU-156526 https://reactome.org/PathwayBrowser/#/R-MMU-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Mus musculus 15378 R-MMU-158609 https://reactome.org/PathwayBrowser/#/R-MMU-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Mus musculus 15378 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 15378 R-MMU-1605797 https://reactome.org/PathwayBrowser/#/R-MMU-1605797 SMPD1 hydrolyzes SPHM IEA Mus musculus 15378 R-MMU-1606273 https://reactome.org/PathwayBrowser/#/R-MMU-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Mus musculus 15378 R-MMU-1606288 https://reactome.org/PathwayBrowser/#/R-MMU-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Mus musculus 15378 R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 15378 R-MMU-1614362 https://reactome.org/PathwayBrowser/#/R-MMU-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Mus musculus 15378 R-MMU-1614605 https://reactome.org/PathwayBrowser/#/R-MMU-1614605 Persulfide sulfur is dioxygenated IEA Mus musculus 15378 R-MMU-162730 https://reactome.org/PathwayBrowser/#/R-MMU-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Mus musculus 15378 R-MMU-163120 https://reactome.org/PathwayBrowser/#/R-MMU-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Mus musculus 15378 R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 15378 R-MMU-163217 https://reactome.org/PathwayBrowser/#/R-MMU-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Mus musculus 15378 R-MMU-1638104 https://reactome.org/PathwayBrowser/#/R-MMU-1638104 UGCG transfers glucose to ceramide IEA Mus musculus 15378 R-MMU-1638845 https://reactome.org/PathwayBrowser/#/R-MMU-1638845 CERK phosphorylates CERA to form C1P IEA Mus musculus 15378 R-MMU-1640164 https://reactome.org/PathwayBrowser/#/R-MMU-1640164 ENPP7 hydrolyzes sphingomyelin IEA Mus musculus 15378 R-MMU-164651 https://reactome.org/PathwayBrowser/#/R-MMU-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Mus musculus 15378 R-MMU-164834 https://reactome.org/PathwayBrowser/#/R-MMU-164834 Enzyme-bound ATP is released IEA Mus musculus 15378 R-MMU-1655453 https://reactome.org/PathwayBrowser/#/R-MMU-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Mus musculus 15378 R-MMU-1655879 https://reactome.org/PathwayBrowser/#/R-MMU-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Mus musculus 15378 R-MMU-1678920 https://reactome.org/PathwayBrowser/#/R-MMU-1678920 TLR processing at low pH IEA Mus musculus 15378 R-MMU-170026 https://reactome.org/PathwayBrowser/#/R-MMU-170026 Protons are translocated from the intermembrane space to the matrix IEA Mus musculus 15378 R-MMU-173597 https://reactome.org/PathwayBrowser/#/R-MMU-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Mus musculus 15378 R-MMU-174389 https://reactome.org/PathwayBrowser/#/R-MMU-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Mus musculus 15378 R-MMU-174392 https://reactome.org/PathwayBrowser/#/R-MMU-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Mus musculus 15378 R-MMU-174438 https://reactome.org/PathwayBrowser/#/R-MMU-174438 Formation of the Flap Intermediate on the C-strand IEA Mus musculus 15378 R-MMU-189421 https://reactome.org/PathwayBrowser/#/R-MMU-189421 CPO transforms COPRO3 to PPGEN9 IEA Mus musculus 15378 R-MMU-189425 https://reactome.org/PathwayBrowser/#/R-MMU-189425 UROD decarboxylates URO3 to COPRO3 IEA Mus musculus 15378 R-MMU-189439 https://reactome.org/PathwayBrowser/#/R-MMU-189439 ALAD condenses 2 dALAs to form PBG IEA Mus musculus 15378 R-MMU-189442 https://reactome.org/PathwayBrowser/#/R-MMU-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Mus musculus 15378 R-MMU-189465 https://reactome.org/PathwayBrowser/#/R-MMU-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Mus musculus 15378 R-MMU-190182 https://reactome.org/PathwayBrowser/#/R-MMU-190182 UROD decarboxylates URO1 to COPRO1 IEA Mus musculus 15378 R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 15378 R-MMU-191323 https://reactome.org/PathwayBrowser/#/R-MMU-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Mus musculus 15378 R-MMU-191352 https://reactome.org/PathwayBrowser/#/R-MMU-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Mus musculus 15378 R-MMU-191402 https://reactome.org/PathwayBrowser/#/R-MMU-191402 Reduction of presqualene diphosphate to form squalene IEA Mus musculus 15378 R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 15378 R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 15378 R-MMU-191999 https://reactome.org/PathwayBrowser/#/R-MMU-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Mus musculus 15378 R-MMU-192033 https://reactome.org/PathwayBrowser/#/R-MMU-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Mus musculus 15378 R-MMU-192036 https://reactome.org/PathwayBrowser/#/R-MMU-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Mus musculus 15378 R-MMU-192042 https://reactome.org/PathwayBrowser/#/R-MMU-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 15378 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 15378 R-MMU-192054 https://reactome.org/PathwayBrowser/#/R-MMU-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Mus musculus 15378 R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 15378 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 15378 R-MMU-192067 https://reactome.org/PathwayBrowser/#/R-MMU-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Mus musculus 15378 R-MMU-192097 https://reactome.org/PathwayBrowser/#/R-MMU-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Mus musculus 15378 R-MMU-192123 https://reactome.org/PathwayBrowser/#/R-MMU-192123 CYP27A1 27-hydroxylates CHOL IEA Mus musculus 15378 R-MMU-192157 https://reactome.org/PathwayBrowser/#/R-MMU-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Mus musculus 15378 R-MMU-192160 https://reactome.org/PathwayBrowser/#/R-MMU-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Mus musculus 15378 R-MMU-192178 https://reactome.org/PathwayBrowser/#/R-MMU-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Mus musculus 15378 R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 15378 R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 15378 R-MMU-193064 https://reactome.org/PathwayBrowser/#/R-MMU-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Mus musculus 15378 R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 15378 R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 15378 R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 15378 R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 15378 R-MMU-193073 https://reactome.org/PathwayBrowser/#/R-MMU-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Mus musculus 15378 R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 15378 R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 15378 R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 15378 R-MMU-193393 https://reactome.org/PathwayBrowser/#/R-MMU-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Mus musculus 15378 R-MMU-193455 https://reactome.org/PathwayBrowser/#/R-MMU-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 15378 R-MMU-193460 https://reactome.org/PathwayBrowser/#/R-MMU-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Mus musculus 15378 R-MMU-193497 https://reactome.org/PathwayBrowser/#/R-MMU-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Mus musculus 15378 R-MMU-193508 https://reactome.org/PathwayBrowser/#/R-MMU-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 15378 R-MMU-193709 https://reactome.org/PathwayBrowser/#/R-MMU-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Mus musculus 15378 R-MMU-193713 https://reactome.org/PathwayBrowser/#/R-MMU-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Mus musculus 15378 R-MMU-193719 https://reactome.org/PathwayBrowser/#/R-MMU-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 15378 R-MMU-193737 https://reactome.org/PathwayBrowser/#/R-MMU-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Mus musculus 15378 R-MMU-193746 https://reactome.org/PathwayBrowser/#/R-MMU-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Mus musculus 15378 R-MMU-193755 https://reactome.org/PathwayBrowser/#/R-MMU-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Mus musculus 15378 R-MMU-193758 https://reactome.org/PathwayBrowser/#/R-MMU-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Mus musculus 15378 R-MMU-193780 https://reactome.org/PathwayBrowser/#/R-MMU-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Mus musculus 15378 R-MMU-193781 https://reactome.org/PathwayBrowser/#/R-MMU-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Mus musculus 15378 R-MMU-193787 https://reactome.org/PathwayBrowser/#/R-MMU-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Mus musculus 15378 R-MMU-193789 https://reactome.org/PathwayBrowser/#/R-MMU-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Mus musculus 15378 R-MMU-193792 https://reactome.org/PathwayBrowser/#/R-MMU-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Mus musculus 15378 R-MMU-193800 https://reactome.org/PathwayBrowser/#/R-MMU-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Mus musculus 15378 R-MMU-193816 https://reactome.org/PathwayBrowser/#/R-MMU-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Mus musculus 15378 R-MMU-193821 https://reactome.org/PathwayBrowser/#/R-MMU-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Mus musculus 15378 R-MMU-193824 https://reactome.org/PathwayBrowser/#/R-MMU-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Mus musculus 15378 R-MMU-193841 https://reactome.org/PathwayBrowser/#/R-MMU-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Mus musculus 15378 R-MMU-193845 https://reactome.org/PathwayBrowser/#/R-MMU-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Mus musculus 15378 R-MMU-193964 https://reactome.org/PathwayBrowser/#/R-MMU-193964 CYP21A2 21-hydroxylates PROG IEA Mus musculus 15378 R-MMU-193965 https://reactome.org/PathwayBrowser/#/R-MMU-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Mus musculus 15378 R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 15378 R-MMU-193995 https://reactome.org/PathwayBrowser/#/R-MMU-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Mus musculus 15378 R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 15378 R-MMU-194017 https://reactome.org/PathwayBrowser/#/R-MMU-194017 CYP11B2 oxidises 11DCORST to CORST IEA Mus musculus 15378 R-MMU-194023 https://reactome.org/PathwayBrowser/#/R-MMU-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Mus musculus 15378 R-MMU-194632 https://reactome.org/PathwayBrowser/#/R-MMU-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Mus musculus 15378 R-MMU-194641 https://reactome.org/PathwayBrowser/#/R-MMU-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15378 R-MMU-194642 https://reactome.org/PathwayBrowser/#/R-MMU-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Mus musculus 15378 R-MMU-194669 https://reactome.org/PathwayBrowser/#/R-MMU-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15378 R-MMU-194674 https://reactome.org/PathwayBrowser/#/R-MMU-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Mus musculus 15378 R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 15378 R-MMU-194689 https://reactome.org/PathwayBrowser/#/R-MMU-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15378 R-MMU-194698 https://reactome.org/PathwayBrowser/#/R-MMU-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Mus musculus 15378 R-MMU-194718 https://reactome.org/PathwayBrowser/#/R-MMU-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Mus musculus 15378 R-MMU-195664 https://reactome.org/PathwayBrowser/#/R-MMU-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Mus musculus 15378 R-MMU-196060 https://reactome.org/PathwayBrowser/#/R-MMU-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Mus musculus 15378 R-MMU-196350 https://reactome.org/PathwayBrowser/#/R-MMU-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Mus musculus 15378 R-MMU-196372 https://reactome.org/PathwayBrowser/#/R-MMU-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Mus musculus 15378 R-MMU-196402 https://reactome.org/PathwayBrowser/#/R-MMU-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Mus musculus 15378 R-MMU-196417 https://reactome.org/PathwayBrowser/#/R-MMU-196417 Reduction of desmosterol to cholesterol IEA Mus musculus 15378 R-MMU-196753 https://reactome.org/PathwayBrowser/#/R-MMU-196753 2xPPCS ligates PPanK with Cys IEA Mus musculus 15378 R-MMU-196754 https://reactome.org/PathwayBrowser/#/R-MMU-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Mus musculus 15378 R-MMU-196773 https://reactome.org/PathwayBrowser/#/R-MMU-196773 COASY phosphorylates DP-CoA IEA Mus musculus 15378 R-MMU-196840 https://reactome.org/PathwayBrowser/#/R-MMU-196840 3xPPCDC:3FMN decarboxylates PPC IEA Mus musculus 15378 R-MMU-196857 https://reactome.org/PathwayBrowser/#/R-MMU-196857 PANK2 phosphorylates PanK IEA Mus musculus 15378 R-MMU-196929 https://reactome.org/PathwayBrowser/#/R-MMU-196929 FLAD1 phosphorylates FMN IEA Mus musculus 15378 R-MMU-196955 https://reactome.org/PathwayBrowser/#/R-MMU-196955 2xENPP1 hydrolyzes FAD to FMN IEA Mus musculus 15378 R-MMU-196964 https://reactome.org/PathwayBrowser/#/R-MMU-196964 RFK:Mg2+ phosphorylates RIB IEA Mus musculus 15378 R-MMU-197186 https://reactome.org/PathwayBrowser/#/R-MMU-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Mus musculus 15378 R-MMU-197268 https://reactome.org/PathwayBrowser/#/R-MMU-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Mus musculus 15378 R-MMU-197963 https://reactome.org/PathwayBrowser/#/R-MMU-197963 DHFR2 reduces FOLA to DHF IEA Mus musculus 15378 R-MMU-197972 https://reactome.org/PathwayBrowser/#/R-MMU-197972 DHF is reduced to tetrahydrofolate (THF) IEA Mus musculus 15378 R-MMU-198824 https://reactome.org/PathwayBrowser/#/R-MMU-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Mus musculus 15378 R-MMU-199203 https://reactome.org/PathwayBrowser/#/R-MMU-199203 PANK1/3 phosphorylate PanK IEA Mus musculus 15378 R-MMU-200644 https://reactome.org/PathwayBrowser/#/R-MMU-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Mus musculus 15378 R-MMU-200676 https://reactome.org/PathwayBrowser/#/R-MMU-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Mus musculus 15378 R-MMU-200718 https://reactome.org/PathwayBrowser/#/R-MMU-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Mus musculus 15378 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 15378 R-MMU-204617 https://reactome.org/PathwayBrowser/#/R-MMU-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Mus musculus 15378 R-MMU-204647 https://reactome.org/PathwayBrowser/#/R-MMU-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Mus musculus 15378 R-MMU-204662 https://reactome.org/PathwayBrowser/#/R-MMU-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Mus musculus 15378 R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 15378 R-MMU-209772 https://reactome.org/PathwayBrowser/#/R-MMU-209772 Thyroxine is deiodinated to triiodothyronine IEA Mus musculus 15378 R-MMU-209821 https://reactome.org/PathwayBrowser/#/R-MMU-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Mus musculus 15378 R-MMU-209845 https://reactome.org/PathwayBrowser/#/R-MMU-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Mus musculus 15378 R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 15378 R-MMU-209903 https://reactome.org/PathwayBrowser/#/R-MMU-209903 Noradrenaline is converted to adrenaline IEA Mus musculus 15378 R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 15378 R-MMU-210404 https://reactome.org/PathwayBrowser/#/R-MMU-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Mus musculus 15378 R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus 15378 R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 15378 R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 15378 R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 15378 R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 15378 R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 15378 R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 15378 R-MMU-211923 https://reactome.org/PathwayBrowser/#/R-MMU-211923 CYP26C1 4-hydroxylates 9cRA IEA Mus musculus 15378 R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 15378 R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 15378 R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 15378 R-MMU-211950 https://reactome.org/PathwayBrowser/#/R-MMU-211950 CYP24A1 24-hydroxylates CTL IEA Mus musculus 15378 R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 15378 R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 15378 R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 15378 R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 15378 R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 15378 R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 15378 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 15378 R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 15378 R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 15378 R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 15378 R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 15378 R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 15378 R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 15378 R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 15378 R-MMU-2161187 https://reactome.org/PathwayBrowser/#/R-MMU-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Mus musculus 15378 R-MMU-2161549 https://reactome.org/PathwayBrowser/#/R-MMU-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Mus musculus 15378 R-MMU-2161614 https://reactome.org/PathwayBrowser/#/R-MMU-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Mus musculus 15378 R-MMU-2161638 https://reactome.org/PathwayBrowser/#/R-MMU-2161638 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by Ptgr2 TAS Mus musculus 15378 R-MMU-2161651 https://reactome.org/PathwayBrowser/#/R-MMU-2161651 PGE2 is converted to PGF2a by CBR1 IEA Mus musculus 15378 R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus 15378 R-MMU-2161779 https://reactome.org/PathwayBrowser/#/R-MMU-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Mus musculus 15378 R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus 15378 R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Mus musculus 15378 R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 15378 R-MMU-2161890 https://reactome.org/PathwayBrowser/#/R-MMU-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Mus musculus 15378 R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Mus musculus 15378 R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 15378 R-MMU-2161951 https://reactome.org/PathwayBrowser/#/R-MMU-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Mus musculus 15378 R-MMU-2162078 https://reactome.org/PathwayBrowser/#/R-MMU-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Mus musculus 15378 R-MMU-2162186 https://reactome.org/PathwayBrowser/#/R-MMU-2162186 COQ3 methylates DeMQ10H2 IEA Mus musculus 15378 R-MMU-2162188 https://reactome.org/PathwayBrowser/#/R-MMU-2162188 COQ5 methylates MDMQ10H2 IEA Mus musculus 15378 R-MMU-2162193 https://reactome.org/PathwayBrowser/#/R-MMU-2162193 COQ3 methylates DHDB IEA Mus musculus 15378 R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 15378 R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 15378 R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 15378 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 15378 R-MMU-2395512 https://reactome.org/PathwayBrowser/#/R-MMU-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Mus musculus 15378 R-MMU-2395517 https://reactome.org/PathwayBrowser/#/R-MMU-2395517 NADPH transfers electrons to FDXR IEA Mus musculus 15378 R-MMU-2395818 https://reactome.org/PathwayBrowser/#/R-MMU-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Mus musculus 15378 R-MMU-2395849 https://reactome.org/PathwayBrowser/#/R-MMU-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 15378 R-MMU-2395869 https://reactome.org/PathwayBrowser/#/R-MMU-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 15378 R-MMU-2395872 https://reactome.org/PathwayBrowser/#/R-MMU-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Mus musculus 15378 R-MMU-2395873 https://reactome.org/PathwayBrowser/#/R-MMU-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Mus musculus 15378 R-MMU-2395876 https://reactome.org/PathwayBrowser/#/R-MMU-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 15378 R-MMU-2395879 https://reactome.org/PathwayBrowser/#/R-MMU-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 15378 R-MMU-2395965 https://reactome.org/PathwayBrowser/#/R-MMU-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Mus musculus 15378 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 15378 R-MMU-2454081 https://reactome.org/PathwayBrowser/#/R-MMU-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Mus musculus 15378 R-MMU-2464822 https://reactome.org/PathwayBrowser/#/R-MMU-2464822 RDH12 reduces atRAL to atROL IEA Mus musculus 15378 R-MMU-2465940 https://reactome.org/PathwayBrowser/#/R-MMU-2465940 atRAL is reduced to atROL IEA Mus musculus 15378 R-MMU-2509793 https://reactome.org/PathwayBrowser/#/R-MMU-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Mus musculus 15378 R-MMU-2509816 https://reactome.org/PathwayBrowser/#/R-MMU-2509816 NUDT16 hydrolyses IDP to IMP IEA Mus musculus 15378 R-MMU-2509827 https://reactome.org/PathwayBrowser/#/R-MMU-2509827 ITPA hydrolyses ITP to IMP IEA Mus musculus 15378 R-MMU-2509831 https://reactome.org/PathwayBrowser/#/R-MMU-2509831 ITPA hydrolyses XTP to XMP IEA Mus musculus 15378 R-MMU-2509838 https://reactome.org/PathwayBrowser/#/R-MMU-2509838 ITPA hydrolyses dITP to dIMP IEA Mus musculus 15378 R-MMU-2534378 https://reactome.org/PathwayBrowser/#/R-MMU-2534378 Hv1 Mediated H+ Permeability IEA Mus musculus 15378 R-MMU-264615 https://reactome.org/PathwayBrowser/#/R-MMU-264615 Loading of acetylcholine in synaptic vesicles IEA Mus musculus 15378 R-MMU-2671885 https://reactome.org/PathwayBrowser/#/R-MMU-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Mus musculus 15378 R-MMU-2730692 https://reactome.org/PathwayBrowser/#/R-MMU-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Mus musculus 15378 R-MMU-2730951 https://reactome.org/PathwayBrowser/#/R-MMU-2730951 Clcn3 exchanges Cl- for H+ TAS Mus musculus 15378 R-MMU-2730959 https://reactome.org/PathwayBrowser/#/R-MMU-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Mus musculus 15378 R-MMU-2855252 https://reactome.org/PathwayBrowser/#/R-MMU-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Mus musculus 15378 R-MMU-2872444 https://reactome.org/PathwayBrowser/#/R-MMU-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Mus musculus 15378 R-MMU-2872452 https://reactome.org/PathwayBrowser/#/R-MMU-2872452 Slc9c1 exchanges Na+ for H+ TAS Mus musculus 15378 R-MMU-2889070 https://reactome.org/PathwayBrowser/#/R-MMU-2889070 SLC9B2 exchanges Na+ for H+ IEA Mus musculus 15378 R-MMU-3095889 https://reactome.org/PathwayBrowser/#/R-MMU-3095889 MMACHC dealkylates RCbl IEA Mus musculus 15378 R-MMU-3149518 https://reactome.org/PathwayBrowser/#/R-MMU-3149518 MTRR reduces cob(II)alamin to meCbl IEA Mus musculus 15378 R-MMU-3149519 https://reactome.org/PathwayBrowser/#/R-MMU-3149519 MMACHC decyanates CNCbl IEA Mus musculus 15378 R-MMU-3159253 https://reactome.org/PathwayBrowser/#/R-MMU-3159253 MMAB adenosylates cob(I)alamin IEA Mus musculus 15378 R-MMU-3299680 https://reactome.org/PathwayBrowser/#/R-MMU-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Mus musculus 15378 R-MMU-3299682 https://reactome.org/PathwayBrowser/#/R-MMU-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Mus musculus 15378 R-MMU-3299691 https://reactome.org/PathwayBrowser/#/R-MMU-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Mus musculus 15378 R-MMU-3323050 https://reactome.org/PathwayBrowser/#/R-MMU-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Mus musculus 15378 R-MMU-3323079 https://reactome.org/PathwayBrowser/#/R-MMU-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 15378 R-MMU-350869 https://reactome.org/PathwayBrowser/#/R-MMU-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Mus musculus 15378 R-MMU-350901 https://reactome.org/PathwayBrowser/#/R-MMU-350901 Iodide is organified IEA Mus musculus 15378 R-MMU-352174 https://reactome.org/PathwayBrowser/#/R-MMU-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Mus musculus 15378 R-MMU-352182 https://reactome.org/PathwayBrowser/#/R-MMU-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Mus musculus 15378 R-MMU-372448 https://reactome.org/PathwayBrowser/#/R-MMU-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Mus musculus 15378 R-MMU-373867 https://reactome.org/PathwayBrowser/#/R-MMU-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-MMU-373875 https://reactome.org/PathwayBrowser/#/R-MMU-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Mus musculus 15378 R-MMU-375405 https://reactome.org/PathwayBrowser/#/R-MMU-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Mus musculus 15378 R-MMU-375417 https://reactome.org/PathwayBrowser/#/R-MMU-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Mus musculus 15378 R-MMU-3777112 https://reactome.org/PathwayBrowser/#/R-MMU-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Mus musculus 15378 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15378 R-MMU-380608 https://reactome.org/PathwayBrowser/#/R-MMU-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Mus musculus 15378 R-MMU-389540 https://reactome.org/PathwayBrowser/#/R-MMU-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 15378 R-MMU-389550 https://reactome.org/PathwayBrowser/#/R-MMU-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 15378 R-MMU-389609 https://reactome.org/PathwayBrowser/#/R-MMU-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Mus musculus 15378 R-MMU-389826 https://reactome.org/PathwayBrowser/#/R-MMU-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Mus musculus 15378 R-MMU-389995 https://reactome.org/PathwayBrowser/#/R-MMU-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Mus musculus 15378 R-MMU-390251 https://reactome.org/PathwayBrowser/#/R-MMU-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 15378 R-MMU-390425 https://reactome.org/PathwayBrowser/#/R-MMU-390425 FAR1 reduces PalmCoA to HXOL IEA Mus musculus 15378 R-MMU-390438 https://reactome.org/PathwayBrowser/#/R-MMU-390438 FAR2 reduces PalmCoA to HXOL IEA Mus musculus 15378 R-MMU-418365 https://reactome.org/PathwayBrowser/#/R-MMU-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Mus musculus 15378 R-MMU-425577 https://reactome.org/PathwayBrowser/#/R-MMU-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Mus musculus 15378 R-MMU-425965 https://reactome.org/PathwayBrowser/#/R-MMU-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Mus musculus 15378 R-MMU-425983 https://reactome.org/PathwayBrowser/#/R-MMU-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Mus musculus 15378 R-MMU-425994 https://reactome.org/PathwayBrowser/#/R-MMU-425994 Na+/H+ exchanger transport (at cell membrane) IEA Mus musculus 15378 R-MMU-426015 https://reactome.org/PathwayBrowser/#/R-MMU-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Mus musculus 15378 R-MMU-426043 https://reactome.org/PathwayBrowser/#/R-MMU-426043 2-AG hydrolysis to arachidonate by MAGL IEA Mus musculus 15378 R-MMU-427555 https://reactome.org/PathwayBrowser/#/R-MMU-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Mus musculus 15378 R-MMU-427910 https://reactome.org/PathwayBrowser/#/R-MMU-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Mus musculus 15378 R-MMU-427998 https://reactome.org/PathwayBrowser/#/R-MMU-427998 Proton-coupled di- and tri-peptide cotransport IEA Mus musculus 15378 R-MMU-428007 https://reactome.org/PathwayBrowser/#/R-MMU-428007 Proton-coupled histidine and di-peptide cotransport IEA Mus musculus 15378 R-MMU-428015 https://reactome.org/PathwayBrowser/#/R-MMU-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Mus musculus 15378 R-MMU-428052 https://reactome.org/PathwayBrowser/#/R-MMU-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Mus musculus 15378 R-MMU-428123 https://reactome.org/PathwayBrowser/#/R-MMU-428123 KDSR reduces 3-ketosphingoid IEA Mus musculus 15378 R-MMU-428127 https://reactome.org/PathwayBrowser/#/R-MMU-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Mus musculus 15378 R-MMU-428185 https://reactome.org/PathwayBrowser/#/R-MMU-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Mus musculus 15378 R-MMU-428259 https://reactome.org/PathwayBrowser/#/R-MMU-428259 DEGS1 dehydrogenates dihydroceramide IEA Mus musculus 15378 R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 15378 R-MMU-428273 https://reactome.org/PathwayBrowser/#/R-MMU-428273 SPHK1 phosphorylates sphingoid IEA Mus musculus 15378 R-MMU-428585 https://reactome.org/PathwayBrowser/#/R-MMU-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Mus musculus 15378 R-MMU-428625 https://reactome.org/PathwayBrowser/#/R-MMU-428625 Vesicular inhibitory amino acid transport IEA Mus musculus 15378 R-MMU-429101 https://reactome.org/PathwayBrowser/#/R-MMU-429101 HMIT co-transports myo-inositol with a proton IEA Mus musculus 15378 R-MMU-429157 https://reactome.org/PathwayBrowser/#/R-MMU-429157 ABCC4 accumulation of dense granule contents IEA Mus musculus 15378 R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-MMU-434650 https://reactome.org/PathwayBrowser/#/R-MMU-434650 MATEs mediate extrusion of xenobiotics IEA Mus musculus 15378 R-MMU-435171 https://reactome.org/PathwayBrowser/#/R-MMU-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Mus musculus 15378 R-MMU-435349 https://reactome.org/PathwayBrowser/#/R-MMU-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-MMU-444393 https://reactome.org/PathwayBrowser/#/R-MMU-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Mus musculus 15378 R-MMU-444419 https://reactome.org/PathwayBrowser/#/R-MMU-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Mus musculus 15378 R-MMU-444731 https://reactome.org/PathwayBrowser/#/R-MMU-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Mus musculus 15378 R-MMU-446277 https://reactome.org/PathwayBrowser/#/R-MMU-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Mus musculus 15378 R-MMU-446278 https://reactome.org/PathwayBrowser/#/R-MMU-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Mus musculus 15378 R-MMU-450971 https://reactome.org/PathwayBrowser/#/R-MMU-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Mus musculus 15378 R-MMU-469659 https://reactome.org/PathwayBrowser/#/R-MMU-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Mus musculus 15378 R-MMU-504054 https://reactome.org/PathwayBrowser/#/R-MMU-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Mus musculus 15378 R-MMU-508040 https://reactome.org/PathwayBrowser/#/R-MMU-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Mus musculus 15378 R-MMU-508369 https://reactome.org/PathwayBrowser/#/R-MMU-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Mus musculus 15378 R-MMU-508473 https://reactome.org/PathwayBrowser/#/R-MMU-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Mus musculus 15378 R-MMU-514604 https://reactome.org/PathwayBrowser/#/R-MMU-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Mus musculus 15378 R-MMU-5218841 https://reactome.org/PathwayBrowser/#/R-MMU-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Mus musculus 15378 R-MMU-5263614 https://reactome.org/PathwayBrowser/#/R-MMU-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Mus musculus 15378 R-MMU-5263616 https://reactome.org/PathwayBrowser/#/R-MMU-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Mus musculus 15378 R-MMU-5340130 https://reactome.org/PathwayBrowser/#/R-MMU-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Mus musculus 15378 R-MMU-5340226 https://reactome.org/PathwayBrowser/#/R-MMU-5340226 CYGB dioxygenates NO IEA Mus musculus 15378 R-MMU-5362518 https://reactome.org/PathwayBrowser/#/R-MMU-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Mus musculus 15378 R-MMU-5362522 https://reactome.org/PathwayBrowser/#/R-MMU-5362522 ALDHs oxidise atRAL to atRA IEA Mus musculus 15378 R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 15378 R-MMU-5362564 https://reactome.org/PathwayBrowser/#/R-MMU-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Mus musculus 15378 R-MMU-5362721 https://reactome.org/PathwayBrowser/#/R-MMU-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Mus musculus 15378 R-MMU-5419165 https://reactome.org/PathwayBrowser/#/R-MMU-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Mus musculus 15378 R-MMU-5423637 https://reactome.org/PathwayBrowser/#/R-MMU-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Mus musculus 15378 R-MMU-5423647 https://reactome.org/PathwayBrowser/#/R-MMU-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Mus musculus 15378 R-MMU-5423664 https://reactome.org/PathwayBrowser/#/R-MMU-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Mus musculus 15378 R-MMU-5423672 https://reactome.org/PathwayBrowser/#/R-MMU-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Mus musculus 15378 R-MMU-5423678 https://reactome.org/PathwayBrowser/#/R-MMU-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Mus musculus 15378 R-MMU-548818 https://reactome.org/PathwayBrowser/#/R-MMU-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Mus musculus 15378 R-MMU-548831 https://reactome.org/PathwayBrowser/#/R-MMU-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Mus musculus 15378 R-MMU-5602295 https://reactome.org/PathwayBrowser/#/R-MMU-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Mus musculus 15378 R-MMU-5615668 https://reactome.org/PathwayBrowser/#/R-MMU-5615668 AKR1C3 reduces atRAL to atROL IEA Mus musculus 15378 R-MMU-5623643 https://reactome.org/PathwayBrowser/#/R-MMU-5623643 RDH13 reduces atRAL to atROL IEA Mus musculus 15378 R-MMU-5652172 https://reactome.org/PathwayBrowser/#/R-MMU-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Mus musculus 15378 R-MMU-5652195 https://reactome.org/PathwayBrowser/#/R-MMU-5652195 SORD oxidizes D-sorbitol to Fru IEA Mus musculus 15378 R-MMU-5661240 https://reactome.org/PathwayBrowser/#/R-MMU-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Mus musculus 15378 R-MMU-5661256 https://reactome.org/PathwayBrowser/#/R-MMU-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Mus musculus 15378 R-MMU-5661290 https://reactome.org/PathwayBrowser/#/R-MMU-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Mus musculus 15378 R-MMU-5662471 https://reactome.org/PathwayBrowser/#/R-MMU-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Mus musculus 15378 R-MMU-5662662 https://reactome.org/PathwayBrowser/#/R-MMU-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Mus musculus 15378 R-MMU-5668629 https://reactome.org/PathwayBrowser/#/R-MMU-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Mus musculus 15378 R-MMU-5668718 https://reactome.org/PathwayBrowser/#/R-MMU-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 15378 R-MMU-5668731 https://reactome.org/PathwayBrowser/#/R-MMU-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 15378 R-MMU-5678327 https://reactome.org/PathwayBrowser/#/R-MMU-5678327 MIOX oxidises Ins to GlcA IEA Mus musculus 15378 R-MMU-5690565 https://reactome.org/PathwayBrowser/#/R-MMU-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Mus musculus 15378 R-MMU-5691107 https://reactome.org/PathwayBrowser/#/R-MMU-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Mus musculus 15378 R-MMU-5692237 https://reactome.org/PathwayBrowser/#/R-MMU-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Mus musculus 15378 R-MMU-5692261 https://reactome.org/PathwayBrowser/#/R-MMU-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Mus musculus 15378 R-MMU-5692283 https://reactome.org/PathwayBrowser/#/R-MMU-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Mus musculus 15378 R-MMU-5693347 https://reactome.org/PathwayBrowser/#/R-MMU-5693347 CRYM reduces P2C to PPCA IEA Mus musculus 15378 R-MMU-5693390 https://reactome.org/PathwayBrowser/#/R-MMU-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Mus musculus 15378 R-MMU-5693681 https://reactome.org/PathwayBrowser/#/R-MMU-5693681 DUOX1,2 reduce O2 to H2O2 IEA Mus musculus 15378 R-MMU-5693691 https://reactome.org/PathwayBrowser/#/R-MMU-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Mus musculus 15378 R-MMU-5693761 https://reactome.org/PathwayBrowser/#/R-MMU-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Mus musculus 15378 R-MMU-5694018 https://reactome.org/PathwayBrowser/#/R-MMU-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Mus musculus 15378 R-MMU-5694462 https://reactome.org/PathwayBrowser/#/R-MMU-5694462 ABHD6,12 hydrolyse 3AG IEA Mus musculus 15378 R-MMU-5696080 https://reactome.org/PathwayBrowser/#/R-MMU-5696080 ALDH3B1 oxidises HXAL to PALM IEA Mus musculus 15378 R-MMU-5696091 https://reactome.org/PathwayBrowser/#/R-MMU-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Mus musculus 15378 R-MMU-5696101 https://reactome.org/PathwayBrowser/#/R-MMU-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Mus musculus 15378 R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 15378 R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 15378 R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 15378 R-MMU-5696457 https://reactome.org/PathwayBrowser/#/R-MMU-5696457 BDH2 dehydrogenates 3HBA IEA Mus musculus 15378 R-MMU-5696822 https://reactome.org/PathwayBrowser/#/R-MMU-5696822 AKR1B15 reduces EST17b to E1 IEA Mus musculus 15378 R-MMU-5696838 https://reactome.org/PathwayBrowser/#/R-MMU-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Mus musculus 15378 R-MMU-597628 https://reactome.org/PathwayBrowser/#/R-MMU-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Mus musculus 15378 R-MMU-6783221 https://reactome.org/PathwayBrowser/#/R-MMU-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Mus musculus 15378 R-MMU-6783939 https://reactome.org/PathwayBrowser/#/R-MMU-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 15378 R-MMU-6783955 https://reactome.org/PathwayBrowser/#/R-MMU-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 15378 R-MMU-6784399 https://reactome.org/PathwayBrowser/#/R-MMU-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Mus musculus 15378 R-MMU-6785933 https://reactome.org/PathwayBrowser/#/R-MMU-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Mus musculus 15378 R-MMU-6786239 https://reactome.org/PathwayBrowser/#/R-MMU-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Mus musculus 15378 R-MMU-6786720 https://reactome.org/PathwayBrowser/#/R-MMU-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Mus musculus 15378 R-MMU-6787642 https://reactome.org/PathwayBrowser/#/R-MMU-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Mus musculus 15378 R-MMU-6788999 https://reactome.org/PathwayBrowser/#/R-MMU-6788999 HV1-mediated H+ transfer IEA Mus musculus 15378 R-MMU-6789031 https://reactome.org/PathwayBrowser/#/R-MMU-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 15378 R-MMU-6789092 https://reactome.org/PathwayBrowser/#/R-MMU-6789092 NOX2 generates superoxide anion from oxygen IEA Mus musculus 15378 R-MMU-6789126 https://reactome.org/PathwayBrowser/#/R-MMU-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 15378 R-MMU-6793590 https://reactome.org/PathwayBrowser/#/R-MMU-6793590 LIPT2 transfers octanoyl group to GCSH IEA Mus musculus 15378 R-MMU-6793591 https://reactome.org/PathwayBrowser/#/R-MMU-6793591 LIAS synthesizes lipoyl-GCSH IEA Mus musculus 15378 R-MMU-6799495 https://reactome.org/PathwayBrowser/#/R-MMU-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Mus musculus 15378 R-MMU-6801342 https://reactome.org/PathwayBrowser/#/R-MMU-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Mus musculus 15378 R-MMU-6803771 https://reactome.org/PathwayBrowser/#/R-MMU-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Mus musculus 15378 R-MMU-6806647 https://reactome.org/PathwayBrowser/#/R-MMU-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 15378 R-MMU-6806831 https://reactome.org/PathwayBrowser/#/R-MMU-6806831 CYB5Rs reduce MetHb to HbA IEA Mus musculus 15378 R-MMU-6806967 https://reactome.org/PathwayBrowser/#/R-MMU-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Mus musculus 15378 R-MMU-6807053 https://reactome.org/PathwayBrowser/#/R-MMU-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Mus musculus 15378 R-MMU-6807055 https://reactome.org/PathwayBrowser/#/R-MMU-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Mus musculus 15378 R-MMU-6807064 https://reactome.org/PathwayBrowser/#/R-MMU-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Mus musculus 15378 R-MMU-6807557 https://reactome.org/PathwayBrowser/#/R-MMU-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Mus musculus 15378 R-MMU-6807826 https://reactome.org/PathwayBrowser/#/R-MMU-6807826 LDHAL6B reduces PYR to LACT IEA Mus musculus 15378 R-MMU-6808464 https://reactome.org/PathwayBrowser/#/R-MMU-6808464 ALDH3B2 oxidises HXAL to PALM IEA Mus musculus 15378 R-MMU-6808487 https://reactome.org/PathwayBrowser/#/R-MMU-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 15378 R-MMU-6808496 https://reactome.org/PathwayBrowser/#/R-MMU-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 15378 R-MMU-6809264 https://reactome.org/PathwayBrowser/#/R-MMU-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 15378 R-MMU-6809287 https://reactome.org/PathwayBrowser/#/R-MMU-6809287 NUDT12 hydrolyses NADH to NMNH IEA Mus musculus 15378 R-MMU-6809810 https://reactome.org/PathwayBrowser/#/R-MMU-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Mus musculus 15378 R-MMU-6810594 https://reactome.org/PathwayBrowser/#/R-MMU-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 15378 R-MMU-6813749 https://reactome.org/PathwayBrowser/#/R-MMU-6813749 ALDH1A1 oxidises GA to DGA IEA Mus musculus 15378 R-MMU-6814153 https://reactome.org/PathwayBrowser/#/R-MMU-6814153 ADO oxidises 2AET to HTAU IEA Mus musculus 15378 R-MMU-70333 https://reactome.org/PathwayBrowser/#/R-MMU-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Mus musculus 15378 R-MMU-70377 https://reactome.org/PathwayBrowser/#/R-MMU-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Mus musculus 15378 R-MMU-70420 https://reactome.org/PathwayBrowser/#/R-MMU-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Mus musculus 15378 R-MMU-70449 https://reactome.org/PathwayBrowser/#/R-MMU-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Mus musculus 15378 R-MMU-70467 https://reactome.org/PathwayBrowser/#/R-MMU-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Mus musculus 15378 R-MMU-70482 https://reactome.org/PathwayBrowser/#/R-MMU-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Mus musculus 15378 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 15378 R-MMU-70510 https://reactome.org/PathwayBrowser/#/R-MMU-70510 LDH tetramer oxidises LACT to PYR IEA Mus musculus 15378 R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Mus musculus 15378 R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Mus musculus 15378 R-MMU-70664 https://reactome.org/PathwayBrowser/#/R-MMU-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 15378 R-MMU-70670 https://reactome.org/PathwayBrowser/#/R-MMU-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Mus musculus 15378 R-MMU-70679 https://reactome.org/PathwayBrowser/#/R-MMU-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Mus musculus 15378 R-MMU-70837 https://reactome.org/PathwayBrowser/#/R-MMU-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Mus musculus 15378 R-MMU-70885 https://reactome.org/PathwayBrowser/#/R-MMU-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Mus musculus 15378 R-MMU-70893 https://reactome.org/PathwayBrowser/#/R-MMU-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Mus musculus 15378 R-MMU-70906 https://reactome.org/PathwayBrowser/#/R-MMU-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Mus musculus 15378 R-MMU-70938 https://reactome.org/PathwayBrowser/#/R-MMU-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Mus musculus 15378 R-MMU-70940 https://reactome.org/PathwayBrowser/#/R-MMU-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Mus musculus 15378 R-MMU-70941 https://reactome.org/PathwayBrowser/#/R-MMU-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Mus musculus 15378 R-MMU-70975 https://reactome.org/PathwayBrowser/#/R-MMU-70975 CS acetylates OA to citrate IEA Mus musculus 15378 R-MMU-70979 https://reactome.org/PathwayBrowser/#/R-MMU-70979 MDH2 dimer dehydrogenates MAL IEA Mus musculus 15378 R-MMU-71130 https://reactome.org/PathwayBrowser/#/R-MMU-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Mus musculus 15378 R-MMU-71164 https://reactome.org/PathwayBrowser/#/R-MMU-71164 HGD dioxygenates homogentisate IEA Mus musculus 15378 R-MMU-71181 https://reactome.org/PathwayBrowser/#/R-MMU-71181 FAH cleaves 4FAA IEA Mus musculus 15378 R-MMU-71200 https://reactome.org/PathwayBrowser/#/R-MMU-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Mus musculus 15378 R-MMU-71260 https://reactome.org/PathwayBrowser/#/R-MMU-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Mus musculus 15378 R-MMU-71286 https://reactome.org/PathwayBrowser/#/R-MMU-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Mus musculus 15378 R-MMU-71299 https://reactome.org/PathwayBrowser/#/R-MMU-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Mus musculus 15378 R-MMU-71401 https://reactome.org/PathwayBrowser/#/R-MMU-71401 OGDH dimer decarboxylates 2-OG IEA Mus musculus 15378 R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 15378 R-MMU-71682 https://reactome.org/PathwayBrowser/#/R-MMU-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 15378 R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 15378 R-MMU-71707 https://reactome.org/PathwayBrowser/#/R-MMU-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Mus musculus 15378 R-MMU-71723 https://reactome.org/PathwayBrowser/#/R-MMU-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Mus musculus 15378 R-MMU-71849 https://reactome.org/PathwayBrowser/#/R-MMU-71849 LDH tetramer reduces PYR to LACT IEA Mus musculus 15378 R-MMU-73564 https://reactome.org/PathwayBrowser/#/R-MMU-73564 UMPS dimer decarboxylates OMP to UMP IEA Mus musculus 15378 R-MMU-73571 https://reactome.org/PathwayBrowser/#/R-MMU-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Mus musculus 15378 R-MMU-73573 https://reactome.org/PathwayBrowser/#/R-MMU-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Mus musculus 15378 R-MMU-73577 https://reactome.org/PathwayBrowser/#/R-MMU-73577 CAD hexamer transforms L-Gln to CAP IEA Mus musculus 15378 R-MMU-73585 https://reactome.org/PathwayBrowser/#/R-MMU-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Mus musculus 15378 R-MMU-73589 https://reactome.org/PathwayBrowser/#/R-MMU-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Mus musculus 15378 R-MMU-73591 https://reactome.org/PathwayBrowser/#/R-MMU-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Mus musculus 15378 R-MMU-73596 https://reactome.org/PathwayBrowser/#/R-MMU-73596 dCMP + H2O => dUMP + NH4+ IEA Mus musculus 15378 R-MMU-73616 https://reactome.org/PathwayBrowser/#/R-MMU-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Mus musculus 15378 R-MMU-73618 https://reactome.org/PathwayBrowser/#/R-MMU-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Mus musculus 15378 R-MMU-73620 https://reactome.org/PathwayBrowser/#/R-MMU-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Mus musculus 15378 R-MMU-73646 https://reactome.org/PathwayBrowser/#/R-MMU-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Mus musculus 15378 R-MMU-73647 https://reactome.org/PathwayBrowser/#/R-MMU-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Mus musculus 15378 R-MMU-73666 https://reactome.org/PathwayBrowser/#/R-MMU-73666 dUTP + H2O => dUMP + pyrophosphate IEA Mus musculus 15378 R-MMU-73792 https://reactome.org/PathwayBrowser/#/R-MMU-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Mus musculus 15378 R-MMU-73794 https://reactome.org/PathwayBrowser/#/R-MMU-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Mus musculus 15378 R-MMU-73805 https://reactome.org/PathwayBrowser/#/R-MMU-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Mus musculus 15378 R-MMU-73806 https://reactome.org/PathwayBrowser/#/R-MMU-73806 AIR + CO2 => CAIR IEA Mus musculus 15378 R-MMU-73810 https://reactome.org/PathwayBrowser/#/R-MMU-73810 FGAM + ATP => AIR + ADP + Pi IEA Mus musculus 15378 R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 15378 R-MMU-73813 https://reactome.org/PathwayBrowser/#/R-MMU-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Mus musculus 15378 R-MMU-73814 https://reactome.org/PathwayBrowser/#/R-MMU-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Mus musculus 15378 R-MMU-73912 https://reactome.org/PathwayBrowser/#/R-MMU-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Mus musculus 15378 R-MMU-73920 https://reactome.org/PathwayBrowser/#/R-MMU-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Mus musculus 15378 R-MMU-74255 https://reactome.org/PathwayBrowser/#/R-MMU-74255 Guanine + H2O => Xanthine + NH4+ IEA Mus musculus 15378 R-MMU-74723 https://reactome.org/PathwayBrowser/#/R-MMU-74723 Endosome acidification IEA Mus musculus 15378 R-MMU-74872 https://reactome.org/PathwayBrowser/#/R-MMU-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Mus musculus 15378 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15378 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15378 R-MMU-75872 https://reactome.org/PathwayBrowser/#/R-MMU-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Mus musculus 15378 R-MMU-75883 https://reactome.org/PathwayBrowser/#/R-MMU-75883 DHRS7B reduces GO3P to HXDG3P IEA Mus musculus 15378 R-MMU-75889 https://reactome.org/PathwayBrowser/#/R-MMU-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Mus musculus 15378 R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 15378 R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 15378 R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 15378 R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 15378 R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 15378 R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 15378 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 15378 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 15378 R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 15378 R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 15378 R-MMU-77254 https://reactome.org/PathwayBrowser/#/R-MMU-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Mus musculus 15378 R-MMU-77283 https://reactome.org/PathwayBrowser/#/R-MMU-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Mus musculus 15378 R-MMU-77303 https://reactome.org/PathwayBrowser/#/R-MMU-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Mus musculus 15378 R-MMU-77312 https://reactome.org/PathwayBrowser/#/R-MMU-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Mus musculus 15378 R-MMU-77323 https://reactome.org/PathwayBrowser/#/R-MMU-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Mus musculus 15378 R-MMU-77331 https://reactome.org/PathwayBrowser/#/R-MMU-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Mus musculus 15378 R-MMU-77342 https://reactome.org/PathwayBrowser/#/R-MMU-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Mus musculus 15378 R-MMU-804969 https://reactome.org/PathwayBrowser/#/R-MMU-804969 HSD17B1 hydrogenates E1 to EST17b IEA Mus musculus 15378 R-MMU-8849638 https://reactome.org/PathwayBrowser/#/R-MMU-8849638 Dissociation of the SPINK5:KLK5 complex at low pH IEA Mus musculus 15378 R-MMU-8850846 https://reactome.org/PathwayBrowser/#/R-MMU-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-MMU-8850854 https://reactome.org/PathwayBrowser/#/R-MMU-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-MMU-8851110 https://reactome.org/PathwayBrowser/#/R-MMU-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-MMU-8851129 https://reactome.org/PathwayBrowser/#/R-MMU-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 15378 R-MMU-8862137 https://reactome.org/PathwayBrowser/#/R-MMU-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 15378 R-MMU-8862152 https://reactome.org/PathwayBrowser/#/R-MMU-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Mus musculus 15378 R-MMU-8863494 https://reactome.org/PathwayBrowser/#/R-MMU-8863494 ASICs bind STOML3, (STOM) IEA Mus musculus 15378 R-MMU-8866601 https://reactome.org/PathwayBrowser/#/R-MMU-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Mus musculus 15378 R-MMU-8869606 https://reactome.org/PathwayBrowser/#/R-MMU-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Mus musculus 15378 R-MMU-8869607 https://reactome.org/PathwayBrowser/#/R-MMU-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Mus musculus 15378 R-MMU-8869627 https://reactome.org/PathwayBrowser/#/R-MMU-8869627 NMRK2 phosphorylates NR to yield NMN IEA Mus musculus 15378 R-MMU-8869633 https://reactome.org/PathwayBrowser/#/R-MMU-8869633 NMRK1 phosphorylates NR to yield NMN IEA Mus musculus 15378 R-MMU-8870346 https://reactome.org/PathwayBrowser/#/R-MMU-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Mus musculus 15378 R-MMU-8875623 https://reactome.org/PathwayBrowser/#/R-MMU-8875623 SLC25A18,22 import L-Glu, H+ IEA Mus musculus 15378 R-MMU-8878914 https://reactome.org/PathwayBrowser/#/R-MMU-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Mus musculus 15378 R-MMU-888548 https://reactome.org/PathwayBrowser/#/R-MMU-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Mus musculus 15378 R-MMU-888572 https://reactome.org/PathwayBrowser/#/R-MMU-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Mus musculus 15378 R-MMU-888577 https://reactome.org/PathwayBrowser/#/R-MMU-888577 Synthesis of GABA by GAD2 IEA Mus musculus 15378 R-MMU-8933635 https://reactome.org/PathwayBrowser/#/R-MMU-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Mus musculus 15378 R-MMU-8936442 https://reactome.org/PathwayBrowser/#/R-MMU-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Mus musculus 15378 R-MMU-8938076 https://reactome.org/PathwayBrowser/#/R-MMU-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Mus musculus 15378 R-MMU-8951834 https://reactome.org/PathwayBrowser/#/R-MMU-8951834 Letm1 exchanges protons (mitochondrial intermembrane space) for calcium (mitochondrial matrix) TAS Mus musculus 15378 R-MMU-8952873 https://reactome.org/PathwayBrowser/#/R-MMU-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Mus musculus 15378 R-MMU-8954468 https://reactome.org/PathwayBrowser/#/R-MMU-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Mus musculus 15378 R-MMU-8955030 https://reactome.org/PathwayBrowser/#/R-MMU-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Mus musculus 15378 R-MMU-8955760 https://reactome.org/PathwayBrowser/#/R-MMU-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Mus musculus 15378 R-MMU-8956439 https://reactome.org/PathwayBrowser/#/R-MMU-8956439 Retsat reduces atROL to at-13,14-dhROL TAS Mus musculus 15378 R-MMU-8956458 https://reactome.org/PathwayBrowser/#/R-MMU-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Mus musculus 15378 R-MMU-8959510 https://reactome.org/PathwayBrowser/#/R-MMU-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Mus musculus 15378 R-MMU-8959719 https://reactome.org/PathwayBrowser/#/R-MMU-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Mus musculus 15378 R-MMU-9009950 https://reactome.org/PathwayBrowser/#/R-MMU-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Mus musculus 15378 R-MMU-9011595 https://reactome.org/PathwayBrowser/#/R-MMU-9011595 GSTZ1 dimer dehalogenates DCA IEA Mus musculus 15378 R-MMU-9012016 https://reactome.org/PathwayBrowser/#/R-MMU-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Mus musculus 15378 R-MMU-9012036 https://reactome.org/PathwayBrowser/#/R-MMU-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Mus musculus 15378 R-MMU-9024993 https://reactome.org/PathwayBrowser/#/R-MMU-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Mus musculus 15378 R-MMU-9027043 https://reactome.org/PathwayBrowser/#/R-MMU-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Mus musculus 15378 R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 15378 R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 15378 R-MMU-9037761 https://reactome.org/PathwayBrowser/#/R-MMU-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Mus musculus 15378 R-MMU-917811 https://reactome.org/PathwayBrowser/#/R-MMU-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Mus musculus 15378 R-MMU-917841 https://reactome.org/PathwayBrowser/#/R-MMU-917841 Acidification of Tf:TfR1 containing endosome IEA Mus musculus 15378 R-MMU-917891 https://reactome.org/PathwayBrowser/#/R-MMU-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Mus musculus 15378 R-MMU-917933 https://reactome.org/PathwayBrowser/#/R-MMU-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Mus musculus 15378 R-MMU-917979 https://reactome.org/PathwayBrowser/#/R-MMU-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Mus musculus 15378 R-MMU-937311 https://reactome.org/PathwayBrowser/#/R-MMU-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Mus musculus 15378 R-MMU-9620103 https://reactome.org/PathwayBrowser/#/R-MMU-9620103 ALDH2 transforms GTN to NO IEA Mus musculus 15378 R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-MMU-9650165 https://reactome.org/PathwayBrowser/#/R-MMU-9650165 ASIC trimers bind H+ IEA Mus musculus 15378 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 15378 R-MMU-9705713 https://reactome.org/PathwayBrowser/#/R-MMU-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Mus musculus 15378 R-MMU-9705714 https://reactome.org/PathwayBrowser/#/R-MMU-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Mus musculus 15378 R-MMU-9709098 https://reactome.org/PathwayBrowser/#/R-MMU-9709098 DHFR dimer reduces FOLA to DHF IEA Mus musculus 15378 R-MMU-9727198 https://reactome.org/PathwayBrowser/#/R-MMU-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Mus musculus 15378 R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 15378 R-MMU-9727349 https://reactome.org/PathwayBrowser/#/R-MMU-9727349 XDH dehydrogenates xanthine to form urate IEA Mus musculus 15378 R-MMU-9729538 https://reactome.org/PathwayBrowser/#/R-MMU-9729538 Otop1 transports H+ from the extracellular region to the cytosol TAS Mus musculus 15378 R-MMU-9729881 https://reactome.org/PathwayBrowser/#/R-MMU-9729881 Kcnj2 transports K+ from the extracellular region to the cytosol TAS Mus musculus 15378 R-MMU-9731228 https://reactome.org/PathwayBrowser/#/R-MMU-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Mus musculus 15378 R-MMU-9731590 https://reactome.org/PathwayBrowser/#/R-MMU-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Mus musculus 15378 R-MMU-9731613 https://reactome.org/PathwayBrowser/#/R-MMU-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Mus musculus 15378 R-MMU-9731632 https://reactome.org/PathwayBrowser/#/R-MMU-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Mus musculus 15378 R-MMU-9731661 https://reactome.org/PathwayBrowser/#/R-MMU-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Mus musculus 15378 R-MMU-9748945 https://reactome.org/PathwayBrowser/#/R-MMU-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Mus musculus 15378 R-MMU-9748957 https://reactome.org/PathwayBrowser/#/R-MMU-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Mus musculus 15378 R-MMU-9748979 https://reactome.org/PathwayBrowser/#/R-MMU-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Mus musculus 15378 R-MMU-9748983 https://reactome.org/PathwayBrowser/#/R-MMU-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Mus musculus 15378 R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 15378 R-MMU-9749609 https://reactome.org/PathwayBrowser/#/R-MMU-9749609 BCHE hydrolyzes ASA- IEA Mus musculus 15378 R-MMU-9749647 https://reactome.org/PathwayBrowser/#/R-MMU-9749647 CES2 hydrolyzes ASA- IEA Mus musculus 15378 R-MMU-9749792 https://reactome.org/PathwayBrowser/#/R-MMU-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Mus musculus 15378 R-MMU-9753285 https://reactome.org/PathwayBrowser/#/R-MMU-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Mus musculus 15378 R-MMU-9755937 https://reactome.org/PathwayBrowser/#/R-MMU-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Mus musculus 15378 R-MMU-9756134 https://reactome.org/PathwayBrowser/#/R-MMU-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Mus musculus 15378 R-MMU-9756138 https://reactome.org/PathwayBrowser/#/R-MMU-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Mus musculus 15378 R-MMU-9756156 https://reactome.org/PathwayBrowser/#/R-MMU-9756156 UGT1A3 lactonizes ATV to ATVL IEA Mus musculus 15378 R-MMU-9756162 https://reactome.org/PathwayBrowser/#/R-MMU-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Mus musculus 15378 R-MMU-9756169 https://reactome.org/PathwayBrowser/#/R-MMU-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Mus musculus 15378 R-MMU-9756177 https://reactome.org/PathwayBrowser/#/R-MMU-9756177 PON1,3 hydrolyse ATVL to ATV IEA Mus musculus 15378 R-MMU-9756180 https://reactome.org/PathwayBrowser/#/R-MMU-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Mus musculus 15378 R-MMU-9756183 https://reactome.org/PathwayBrowser/#/R-MMU-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Mus musculus 15378 R-MMU-975629 https://reactome.org/PathwayBrowser/#/R-MMU-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Mus musculus 15378 R-MMU-9757706 https://reactome.org/PathwayBrowser/#/R-MMU-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Mus musculus 15378 R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 15378 R-MMU-9758674 https://reactome.org/PathwayBrowser/#/R-MMU-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Mus musculus 15378 R-MMU-9758682 https://reactome.org/PathwayBrowser/#/R-MMU-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Mus musculus 15378 R-MMU-9759259 https://reactome.org/PathwayBrowser/#/R-MMU-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Mus musculus 15378 R-MMU-9759549 https://reactome.org/PathwayBrowser/#/R-MMU-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Mus musculus 15378 R-MMU-9760094 https://reactome.org/PathwayBrowser/#/R-MMU-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Mus musculus 15378 R-MMU-977348 https://reactome.org/PathwayBrowser/#/R-MMU-977348 PHGDH tetramer dehydrogenates 3PG IEA Mus musculus 15378 R-MMU-9794270 https://reactome.org/PathwayBrowser/#/R-MMU-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Mus musculus 15378 R-MMU-9822592 https://reactome.org/PathwayBrowser/#/R-MMU-9822592 Mettl23 dimethylates histone H3.3 arginine-18 (arginine-17 in the mature protein) TAS Mus musculus 15378 R-MMU-9837337 https://reactome.org/PathwayBrowser/#/R-MMU-9837337 DCAKD phosphorylates DP-CoA IEA Mus musculus 15378 R-MMU-9837342 https://reactome.org/PathwayBrowser/#/R-MMU-9837342 Nudt8 hydrolyzes CoA-SH to PPANT TAS Mus musculus 15378 R-MMU-9843721 https://reactome.org/PathwayBrowser/#/R-MMU-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Mus musculus 15378 R-MMU-9844587 https://reactome.org/PathwayBrowser/#/R-MMU-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Mus musculus 15378 R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 15378 R-MMU-9845516 https://reactome.org/PathwayBrowser/#/R-MMU-9845516 B3GALT4 transfers Gal to gangliosides IEA Mus musculus 15378 R-MMU-9845538 https://reactome.org/PathwayBrowser/#/R-MMU-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Mus musculus 15378 R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 15378 R-MMU-9846305 https://reactome.org/PathwayBrowser/#/R-MMU-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Mus musculus 15378 R-MMU-9846332 https://reactome.org/PathwayBrowser/#/R-MMU-9846332 FUT1,2 transfer fucose to gangliosides IEA Mus musculus 15378 R-MMU-9846477 https://reactome.org/PathwayBrowser/#/R-MMU-9846477 A4GALT transfers galactose to LacCer IEA Mus musculus 15378 R-MMU-9846501 https://reactome.org/PathwayBrowser/#/R-MMU-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Mus musculus 15378 R-MMU-9851347 https://reactome.org/PathwayBrowser/#/R-MMU-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Mus musculus 15378 R-MMU-9853499 https://reactome.org/PathwayBrowser/#/R-MMU-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 15378 R-MMU-9854415 https://reactome.org/PathwayBrowser/#/R-MMU-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Mus musculus 15378 R-MMU-9856871 https://reactome.org/PathwayBrowser/#/R-MMU-9856871 MDH1 reduces OA IEA Mus musculus 15378 R-MMU-9861616 https://reactome.org/PathwayBrowser/#/R-MMU-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 15378 R-MMU-9861642 https://reactome.org/PathwayBrowser/#/R-MMU-9861642 NEK1 phosphorylates ME1 IEA Mus musculus 15378 R-MMU-9861660 https://reactome.org/PathwayBrowser/#/R-MMU-9861660 ME1 tetramer decarboxylates OA to PYR IEA Mus musculus 15378 R-MMU-9861734 https://reactome.org/PathwayBrowser/#/R-MMU-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Mus musculus 15378 R-MTU-868622 https://reactome.org/PathwayBrowser/#/R-MTU-868622 Glucose is transferred from UDP-glucose onto glucose-6-phosphate TAS Mycobacterium tuberculosis 15378 R-MTU-879245 https://reactome.org/PathwayBrowser/#/R-MTU-879245 mycothiol binds formaldehyde and is dehydrogenated TAS Mycobacterium tuberculosis 15378 R-MTU-879266 https://reactome.org/PathwayBrowser/#/R-MTU-879266 mycothiol is oxidized to mycothione TAS Mycobacterium tuberculosis 15378 R-MTU-879293 https://reactome.org/PathwayBrowser/#/R-MTU-879293 formylmycothiol hydrolyzes into mycothiol and formate TAS Mycobacterium tuberculosis 15378 R-MTU-879322 https://reactome.org/PathwayBrowser/#/R-MTU-879322 mycothione is reduced to mycothiol TAS Mycobacterium tuberculosis 15378 R-MTU-936583 https://reactome.org/PathwayBrowser/#/R-MTU-936583 APS is phosphorylated to PAPS TAS Mycobacterium tuberculosis 15378 R-MTU-936655 https://reactome.org/PathwayBrowser/#/R-MTU-936655 sulfite results from reduction of APS TAS Mycobacterium tuberculosis 15378 R-MTU-936703 https://reactome.org/PathwayBrowser/#/R-MTU-936703 sulfite is reduced to sulfide TAS Mycobacterium tuberculosis 15378 R-MTU-9635428 https://reactome.org/PathwayBrowser/#/R-MTU-9635428 FadD26, FadD28 transfer LCFA adenylate ester to Pks5 TAS Mycobacterium tuberculosis 15378 R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 15378 R-MTU-9635480 https://reactome.org/PathwayBrowser/#/R-MTU-9635480 FadD26, FadD28 transfer adenylyl group to a LCFA TAS Mycobacterium tuberculosis 15378 R-MTU-964842 https://reactome.org/PathwayBrowser/#/R-MTU-964842 Shikimate results from hydration of DHS TAS Mycobacterium tuberculosis 15378 R-MTU-964914 https://reactome.org/PathwayBrowser/#/R-MTU-964914 DHQ from DAHP dephosphorylation TAS Mycobacterium tuberculosis 15378 R-OCU-2161568 https://reactome.org/PathwayBrowser/#/R-OCU-2161568 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD TAS Oryctolagus cuniculus 15378 R-PFA-111524 https://reactome.org/PathwayBrowser/#/R-PFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Plasmodium falciparum 15378 R-PFA-1222516 https://reactome.org/PathwayBrowser/#/R-PFA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Plasmodium falciparum 15378 R-PFA-1475022 https://reactome.org/PathwayBrowser/#/R-PFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Plasmodium falciparum 15378 R-PFA-1475026 https://reactome.org/PathwayBrowser/#/R-PFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Plasmodium falciparum 15378 R-PFA-1475028 https://reactome.org/PathwayBrowser/#/R-PFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Plasmodium falciparum 15378 R-PFA-1475032 https://reactome.org/PathwayBrowser/#/R-PFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Plasmodium falciparum 15378 R-PFA-1475435 https://reactome.org/PathwayBrowser/#/R-PFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Plasmodium falciparum 15378 R-PFA-1475436 https://reactome.org/PathwayBrowser/#/R-PFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Plasmodium falciparum 15378 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 15378 R-PFA-1606273 https://reactome.org/PathwayBrowser/#/R-PFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Plasmodium falciparum 15378 R-PFA-189421 https://reactome.org/PathwayBrowser/#/R-PFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Plasmodium falciparum 15378 R-PFA-189425 https://reactome.org/PathwayBrowser/#/R-PFA-189425 UROD decarboxylates URO3 to COPRO3 IEA Plasmodium falciparum 15378 R-PFA-189439 https://reactome.org/PathwayBrowser/#/R-PFA-189439 ALAD condenses 2 dALAs to form PBG IEA Plasmodium falciparum 15378 R-PFA-189442 https://reactome.org/PathwayBrowser/#/R-PFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Plasmodium falciparum 15378 R-PFA-189465 https://reactome.org/PathwayBrowser/#/R-PFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Plasmodium falciparum 15378 R-PFA-190182 https://reactome.org/PathwayBrowser/#/R-PFA-190182 UROD decarboxylates URO1 to COPRO1 IEA Plasmodium falciparum 15378 R-PFA-193064 https://reactome.org/PathwayBrowser/#/R-PFA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Plasmodium falciparum 15378 R-PFA-196753 https://reactome.org/PathwayBrowser/#/R-PFA-196753 2xPPCS ligates PPanK with Cys IEA Plasmodium falciparum 15378 R-PFA-196840 https://reactome.org/PathwayBrowser/#/R-PFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Plasmodium falciparum 15378 R-PFA-196929 https://reactome.org/PathwayBrowser/#/R-PFA-196929 FLAD1 phosphorylates FMN IEA Plasmodium falciparum 15378 R-PFA-196964 https://reactome.org/PathwayBrowser/#/R-PFA-196964 RFK:Mg2+ phosphorylates RIB IEA Plasmodium falciparum 15378 R-PFA-197186 https://reactome.org/PathwayBrowser/#/R-PFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Plasmodium falciparum 15378 R-PFA-200644 https://reactome.org/PathwayBrowser/#/R-PFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Plasmodium falciparum 15378 R-PFA-200718 https://reactome.org/PathwayBrowser/#/R-PFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Plasmodium falciparum 15378 R-PFA-204617 https://reactome.org/PathwayBrowser/#/R-PFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Plasmodium falciparum 15378 R-PFA-204647 https://reactome.org/PathwayBrowser/#/R-PFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Plasmodium falciparum 15378 R-PFA-204662 https://reactome.org/PathwayBrowser/#/R-PFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Plasmodium falciparum 15378 R-PFA-2395512 https://reactome.org/PathwayBrowser/#/R-PFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Plasmodium falciparum 15378 R-PFA-2395517 https://reactome.org/PathwayBrowser/#/R-PFA-2395517 NADPH transfers electrons to FDXR IEA Plasmodium falciparum 15378 R-PFA-2395818 https://reactome.org/PathwayBrowser/#/R-PFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Plasmodium falciparum 15378 R-PFA-2395849 https://reactome.org/PathwayBrowser/#/R-PFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Plasmodium falciparum 15378 R-PFA-2395872 https://reactome.org/PathwayBrowser/#/R-PFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Plasmodium falciparum 15378 R-PFA-2509827 https://reactome.org/PathwayBrowser/#/R-PFA-2509827 ITPA hydrolyses ITP to IMP IEA Plasmodium falciparum 15378 R-PFA-2509831 https://reactome.org/PathwayBrowser/#/R-PFA-2509831 ITPA hydrolyses XTP to XMP IEA Plasmodium falciparum 15378 R-PFA-2509838 https://reactome.org/PathwayBrowser/#/R-PFA-2509838 ITPA hydrolyses dITP to dIMP IEA Plasmodium falciparum 15378 R-PFA-3323079 https://reactome.org/PathwayBrowser/#/R-PFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 15378 R-PFA-418365 https://reactome.org/PathwayBrowser/#/R-PFA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Plasmodium falciparum 15378 R-PFA-426043 https://reactome.org/PathwayBrowser/#/R-PFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Plasmodium falciparum 15378 R-PFA-427910 https://reactome.org/PathwayBrowser/#/R-PFA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Plasmodium falciparum 15378 R-PFA-428123 https://reactome.org/PathwayBrowser/#/R-PFA-428123 KDSR reduces 3-ketosphingoid IEA Plasmodium falciparum 15378 R-PFA-428185 https://reactome.org/PathwayBrowser/#/R-PFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Plasmodium falciparum 15378 R-PFA-429157 https://reactome.org/PathwayBrowser/#/R-PFA-429157 ABCC4 accumulation of dense granule contents IEA Plasmodium falciparum 15378 R-PFA-429714 https://reactome.org/PathwayBrowser/#/R-PFA-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Plasmodium falciparum 15378 R-PFA-434650 https://reactome.org/PathwayBrowser/#/R-PFA-434650 MATEs mediate extrusion of xenobiotics IEA Plasmodium falciparum 15378 R-PFA-435171 https://reactome.org/PathwayBrowser/#/R-PFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Plasmodium falciparum 15378 R-PFA-435349 https://reactome.org/PathwayBrowser/#/R-PFA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Plasmodium falciparum 15378 R-PFA-450971 https://reactome.org/PathwayBrowser/#/R-PFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Plasmodium falciparum 15378 R-PFA-504054 https://reactome.org/PathwayBrowser/#/R-PFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Plasmodium falciparum 15378 R-PFA-5263614 https://reactome.org/PathwayBrowser/#/R-PFA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Plasmodium falciparum 15378 R-PFA-5263616 https://reactome.org/PathwayBrowser/#/R-PFA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Plasmodium falciparum 15378 R-PFA-548818 https://reactome.org/PathwayBrowser/#/R-PFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Plasmodium falciparum 15378 R-PFA-548831 https://reactome.org/PathwayBrowser/#/R-PFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Plasmodium falciparum 15378 R-PFA-5623643 https://reactome.org/PathwayBrowser/#/R-PFA-5623643 RDH13 reduces atRAL to atROL IEA Plasmodium falciparum 15378 R-PFA-5690565 https://reactome.org/PathwayBrowser/#/R-PFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15378 R-PFA-5694018 https://reactome.org/PathwayBrowser/#/R-PFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Plasmodium falciparum 15378 R-PFA-597628 https://reactome.org/PathwayBrowser/#/R-PFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Plasmodium falciparum 15378 R-PFA-6783221 https://reactome.org/PathwayBrowser/#/R-PFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Plasmodium falciparum 15378 R-PFA-6783939 https://reactome.org/PathwayBrowser/#/R-PFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 15378 R-PFA-6783955 https://reactome.org/PathwayBrowser/#/R-PFA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 15378 R-PFA-6787642 https://reactome.org/PathwayBrowser/#/R-PFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Plasmodium falciparum 15378 R-PFA-6801342 https://reactome.org/PathwayBrowser/#/R-PFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Plasmodium falciparum 15378 R-PFA-6806967 https://reactome.org/PathwayBrowser/#/R-PFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Plasmodium falciparum 15378 R-PFA-70377 https://reactome.org/PathwayBrowser/#/R-PFA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Plasmodium falciparum 15378 R-PFA-70420 https://reactome.org/PathwayBrowser/#/R-PFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Plasmodium falciparum 15378 R-PFA-70449 https://reactome.org/PathwayBrowser/#/R-PFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Plasmodium falciparum 15378 R-PFA-70482 https://reactome.org/PathwayBrowser/#/R-PFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Plasmodium falciparum 15378 R-PFA-70664 https://reactome.org/PathwayBrowser/#/R-PFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 15378 R-PFA-70975 https://reactome.org/PathwayBrowser/#/R-PFA-70975 CS acetylates OA to citrate IEA Plasmodium falciparum 15378 R-PFA-70979 https://reactome.org/PathwayBrowser/#/R-PFA-70979 MDH2 dimer dehydrogenates MAL IEA Plasmodium falciparum 15378 R-PFA-71401 https://reactome.org/PathwayBrowser/#/R-PFA-71401 OGDH dimer decarboxylates 2-OG IEA Plasmodium falciparum 15378 R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 15378 R-PFA-71682 https://reactome.org/PathwayBrowser/#/R-PFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 15378 R-PFA-73571 https://reactome.org/PathwayBrowser/#/R-PFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Plasmodium falciparum 15378 R-PFA-73573 https://reactome.org/PathwayBrowser/#/R-PFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Plasmodium falciparum 15378 R-PFA-73577 https://reactome.org/PathwayBrowser/#/R-PFA-73577 CAD hexamer transforms L-Gln to CAP IEA Plasmodium falciparum 15378 R-PFA-73646 https://reactome.org/PathwayBrowser/#/R-PFA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Plasmodium falciparum 15378 R-PFA-73647 https://reactome.org/PathwayBrowser/#/R-PFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Plasmodium falciparum 15378 R-PFA-73666 https://reactome.org/PathwayBrowser/#/R-PFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Plasmodium falciparum 15378 R-PFA-73792 https://reactome.org/PathwayBrowser/#/R-PFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Plasmodium falciparum 15378 R-PFA-73794 https://reactome.org/PathwayBrowser/#/R-PFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Plasmodium falciparum 15378 R-PFA-74723 https://reactome.org/PathwayBrowser/#/R-PFA-74723 Endosome acidification IEA Plasmodium falciparum 15378 R-PFA-75889 https://reactome.org/PathwayBrowser/#/R-PFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Plasmodium falciparum 15378 R-PFA-8847579 https://reactome.org/PathwayBrowser/#/R-PFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15378 R-PFA-8850846 https://reactome.org/PathwayBrowser/#/R-PFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15378 R-PFA-8850854 https://reactome.org/PathwayBrowser/#/R-PFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15378 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15378 R-PFA-8851110 https://reactome.org/PathwayBrowser/#/R-PFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15378 R-PFA-8851129 https://reactome.org/PathwayBrowser/#/R-PFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15378 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15378 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15378 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15378 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15378 R-PFA-8862152 https://reactome.org/PathwayBrowser/#/R-PFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Plasmodium falciparum 15378 R-PFA-8866601 https://reactome.org/PathwayBrowser/#/R-PFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Plasmodium falciparum 15378 R-PFA-8954468 https://reactome.org/PathwayBrowser/#/R-PFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Plasmodium falciparum 15378 R-PFA-8955030 https://reactome.org/PathwayBrowser/#/R-PFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Plasmodium falciparum 15378 R-PFA-8955760 https://reactome.org/PathwayBrowser/#/R-PFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Plasmodium falciparum 15378 R-PFA-8959510 https://reactome.org/PathwayBrowser/#/R-PFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Plasmodium falciparum 15378 R-PFA-9024993 https://reactome.org/PathwayBrowser/#/R-PFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Plasmodium falciparum 15378 R-PFA-917841 https://reactome.org/PathwayBrowser/#/R-PFA-917841 Acidification of Tf:TfR1 containing endosome IEA Plasmodium falciparum 15378 R-PFA-917979 https://reactome.org/PathwayBrowser/#/R-PFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Plasmodium falciparum 15378 R-PFA-9705714 https://reactome.org/PathwayBrowser/#/R-PFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Plasmodium falciparum 15378 R-PFA-9731228 https://reactome.org/PathwayBrowser/#/R-PFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Plasmodium falciparum 15378 R-PFA-9731590 https://reactome.org/PathwayBrowser/#/R-PFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Plasmodium falciparum 15378 R-PFA-9731613 https://reactome.org/PathwayBrowser/#/R-PFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Plasmodium falciparum 15378 R-PFA-9731632 https://reactome.org/PathwayBrowser/#/R-PFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Plasmodium falciparum 15378 R-PFA-9748945 https://reactome.org/PathwayBrowser/#/R-PFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Plasmodium falciparum 15378 R-PFA-9748957 https://reactome.org/PathwayBrowser/#/R-PFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Plasmodium falciparum 15378 R-PFA-9837337 https://reactome.org/PathwayBrowser/#/R-PFA-9837337 DCAKD phosphorylates DP-CoA IEA Plasmodium falciparum 15378 R-PFA-9843721 https://reactome.org/PathwayBrowser/#/R-PFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Plasmodium falciparum 15378 R-PFA-9853499 https://reactome.org/PathwayBrowser/#/R-PFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Plasmodium falciparum 15378 R-PFA-9854415 https://reactome.org/PathwayBrowser/#/R-PFA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Plasmodium falciparum 15378 R-RNO-109343 https://reactome.org/PathwayBrowser/#/R-RNO-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Rattus norvegicus 15378 R-RNO-111524 https://reactome.org/PathwayBrowser/#/R-RNO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Rattus norvegicus 15378 R-RNO-1222376 https://reactome.org/PathwayBrowser/#/R-RNO-1222376 NOX2 generates superoxide from oxygen IEA Rattus norvegicus 15378 R-RNO-1222516 https://reactome.org/PathwayBrowser/#/R-RNO-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Rattus norvegicus 15378 R-RNO-1236967 https://reactome.org/PathwayBrowser/#/R-RNO-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Rattus norvegicus 15378 R-RNO-1237045 https://reactome.org/PathwayBrowser/#/R-RNO-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Rattus norvegicus 15378 R-RNO-1237047 https://reactome.org/PathwayBrowser/#/R-RNO-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Rattus norvegicus 15378 R-RNO-1237059 https://reactome.org/PathwayBrowser/#/R-RNO-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Rattus norvegicus 15378 R-RNO-1237081 https://reactome.org/PathwayBrowser/#/R-RNO-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Rattus norvegicus 15378 R-RNO-1237129 https://reactome.org/PathwayBrowser/#/R-RNO-1237129 Acireductone is created IEA Rattus norvegicus 15378 R-RNO-1237325 https://reactome.org/PathwayBrowser/#/R-RNO-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Rattus norvegicus 15378 R-RNO-1247668 https://reactome.org/PathwayBrowser/#/R-RNO-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Rattus norvegicus 15378 R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 15378 R-RNO-140359 https://reactome.org/PathwayBrowser/#/R-RNO-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Rattus norvegicus 15378 R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 15378 R-RNO-1475017 https://reactome.org/PathwayBrowser/#/R-RNO-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Rattus norvegicus 15378 R-RNO-1475022 https://reactome.org/PathwayBrowser/#/R-RNO-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Rattus norvegicus 15378 R-RNO-1475025 https://reactome.org/PathwayBrowser/#/R-RNO-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Rattus norvegicus 15378 R-RNO-1475026 https://reactome.org/PathwayBrowser/#/R-RNO-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Rattus norvegicus 15378 R-RNO-1475028 https://reactome.org/PathwayBrowser/#/R-RNO-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Rattus norvegicus 15378 R-RNO-1475032 https://reactome.org/PathwayBrowser/#/R-RNO-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Rattus norvegicus 15378 R-RNO-1475435 https://reactome.org/PathwayBrowser/#/R-RNO-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Rattus norvegicus 15378 R-RNO-1475436 https://reactome.org/PathwayBrowser/#/R-RNO-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Rattus norvegicus 15378 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 15378 R-RNO-1497869 https://reactome.org/PathwayBrowser/#/R-RNO-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Rattus norvegicus 15378 R-RNO-1562626 https://reactome.org/PathwayBrowser/#/R-RNO-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Rattus norvegicus 15378 R-RNO-156526 https://reactome.org/PathwayBrowser/#/R-RNO-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15378 R-RNO-158609 https://reactome.org/PathwayBrowser/#/R-RNO-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Rattus norvegicus 15378 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 15378 R-RNO-1605797 https://reactome.org/PathwayBrowser/#/R-RNO-1605797 SMPD1 hydrolyzes SPHM IEA Rattus norvegicus 15378 R-RNO-1606273 https://reactome.org/PathwayBrowser/#/R-RNO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Rattus norvegicus 15378 R-RNO-1606288 https://reactome.org/PathwayBrowser/#/R-RNO-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Rattus norvegicus 15378 R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 15378 R-RNO-1614362 https://reactome.org/PathwayBrowser/#/R-RNO-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Rattus norvegicus 15378 R-RNO-1614605 https://reactome.org/PathwayBrowser/#/R-RNO-1614605 Persulfide sulfur is dioxygenated IEA Rattus norvegicus 15378 R-RNO-162730 https://reactome.org/PathwayBrowser/#/R-RNO-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Rattus norvegicus 15378 R-RNO-163120 https://reactome.org/PathwayBrowser/#/R-RNO-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Rattus norvegicus 15378 R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 15378 R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Rattus norvegicus 15378 R-RNO-1638104 https://reactome.org/PathwayBrowser/#/R-RNO-1638104 UGCG transfers glucose to ceramide IEA Rattus norvegicus 15378 R-RNO-1638845 https://reactome.org/PathwayBrowser/#/R-RNO-1638845 CERK phosphorylates CERA to form C1P IEA Rattus norvegicus 15378 R-RNO-1640164 https://reactome.org/PathwayBrowser/#/R-RNO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Rattus norvegicus 15378 R-RNO-164651 https://reactome.org/PathwayBrowser/#/R-RNO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Rattus norvegicus 15378 R-RNO-164834 https://reactome.org/PathwayBrowser/#/R-RNO-164834 Enzyme-bound ATP is released IEA Rattus norvegicus 15378 R-RNO-1655453 https://reactome.org/PathwayBrowser/#/R-RNO-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Rattus norvegicus 15378 R-RNO-1655879 https://reactome.org/PathwayBrowser/#/R-RNO-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Rattus norvegicus 15378 R-RNO-1678920 https://reactome.org/PathwayBrowser/#/R-RNO-1678920 TLR processing at low pH IEA Rattus norvegicus 15378 R-RNO-170026 https://reactome.org/PathwayBrowser/#/R-RNO-170026 Protons are translocated from the intermembrane space to the matrix IEA Rattus norvegicus 15378 R-RNO-173597 https://reactome.org/PathwayBrowser/#/R-RNO-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Rattus norvegicus 15378 R-RNO-174389 https://reactome.org/PathwayBrowser/#/R-RNO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Rattus norvegicus 15378 R-RNO-174392 https://reactome.org/PathwayBrowser/#/R-RNO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Rattus norvegicus 15378 R-RNO-174438 https://reactome.org/PathwayBrowser/#/R-RNO-174438 Formation of the Flap Intermediate on the C-strand IEA Rattus norvegicus 15378 R-RNO-189421 https://reactome.org/PathwayBrowser/#/R-RNO-189421 CPO transforms COPRO3 to PPGEN9 IEA Rattus norvegicus 15378 R-RNO-189425 https://reactome.org/PathwayBrowser/#/R-RNO-189425 UROD decarboxylates URO3 to COPRO3 IEA Rattus norvegicus 15378 R-RNO-189439 https://reactome.org/PathwayBrowser/#/R-RNO-189439 ALAD condenses 2 dALAs to form PBG IEA Rattus norvegicus 15378 R-RNO-189442 https://reactome.org/PathwayBrowser/#/R-RNO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Rattus norvegicus 15378 R-RNO-189465 https://reactome.org/PathwayBrowser/#/R-RNO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Rattus norvegicus 15378 R-RNO-190182 https://reactome.org/PathwayBrowser/#/R-RNO-190182 UROD decarboxylates URO1 to COPRO1 IEA Rattus norvegicus 15378 R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 15378 R-RNO-191323 https://reactome.org/PathwayBrowser/#/R-RNO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Rattus norvegicus 15378 R-RNO-191352 https://reactome.org/PathwayBrowser/#/R-RNO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Rattus norvegicus 15378 R-RNO-191402 https://reactome.org/PathwayBrowser/#/R-RNO-191402 Reduction of presqualene diphosphate to form squalene IEA Rattus norvegicus 15378 R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 15378 R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 15378 R-RNO-191999 https://reactome.org/PathwayBrowser/#/R-RNO-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Rattus norvegicus 15378 R-RNO-192033 https://reactome.org/PathwayBrowser/#/R-RNO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Rattus norvegicus 15378 R-RNO-192036 https://reactome.org/PathwayBrowser/#/R-RNO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Rattus norvegicus 15378 R-RNO-192042 https://reactome.org/PathwayBrowser/#/R-RNO-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15378 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 15378 R-RNO-192054 https://reactome.org/PathwayBrowser/#/R-RNO-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Rattus norvegicus 15378 R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 15378 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 15378 R-RNO-192067 https://reactome.org/PathwayBrowser/#/R-RNO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Rattus norvegicus 15378 R-RNO-192097 https://reactome.org/PathwayBrowser/#/R-RNO-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Rattus norvegicus 15378 R-RNO-192123 https://reactome.org/PathwayBrowser/#/R-RNO-192123 CYP27A1 27-hydroxylates CHOL IEA Rattus norvegicus 15378 R-RNO-192157 https://reactome.org/PathwayBrowser/#/R-RNO-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Rattus norvegicus 15378 R-RNO-192160 https://reactome.org/PathwayBrowser/#/R-RNO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Rattus norvegicus 15378 R-RNO-192178 https://reactome.org/PathwayBrowser/#/R-RNO-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Rattus norvegicus 15378 R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 15378 R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 15378 R-RNO-193064 https://reactome.org/PathwayBrowser/#/R-RNO-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Rattus norvegicus 15378 R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 15378 R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 15378 R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 15378 R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 15378 R-RNO-193073 https://reactome.org/PathwayBrowser/#/R-RNO-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Rattus norvegicus 15378 R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 15378 R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 15378 R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 15378 R-RNO-193393 https://reactome.org/PathwayBrowser/#/R-RNO-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Rattus norvegicus 15378 R-RNO-193455 https://reactome.org/PathwayBrowser/#/R-RNO-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 15378 R-RNO-193460 https://reactome.org/PathwayBrowser/#/R-RNO-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Rattus norvegicus 15378 R-RNO-193497 https://reactome.org/PathwayBrowser/#/R-RNO-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Rattus norvegicus 15378 R-RNO-193508 https://reactome.org/PathwayBrowser/#/R-RNO-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 15378 R-RNO-193709 https://reactome.org/PathwayBrowser/#/R-RNO-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Rattus norvegicus 15378 R-RNO-193713 https://reactome.org/PathwayBrowser/#/R-RNO-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Rattus norvegicus 15378 R-RNO-193719 https://reactome.org/PathwayBrowser/#/R-RNO-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15378 R-RNO-193737 https://reactome.org/PathwayBrowser/#/R-RNO-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Rattus norvegicus 15378 R-RNO-193746 https://reactome.org/PathwayBrowser/#/R-RNO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 15378 R-RNO-193755 https://reactome.org/PathwayBrowser/#/R-RNO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Rattus norvegicus 15378 R-RNO-193758 https://reactome.org/PathwayBrowser/#/R-RNO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Rattus norvegicus 15378 R-RNO-193780 https://reactome.org/PathwayBrowser/#/R-RNO-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15378 R-RNO-193781 https://reactome.org/PathwayBrowser/#/R-RNO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Rattus norvegicus 15378 R-RNO-193787 https://reactome.org/PathwayBrowser/#/R-RNO-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Rattus norvegicus 15378 R-RNO-193789 https://reactome.org/PathwayBrowser/#/R-RNO-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 15378 R-RNO-193792 https://reactome.org/PathwayBrowser/#/R-RNO-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Rattus norvegicus 15378 R-RNO-193800 https://reactome.org/PathwayBrowser/#/R-RNO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Rattus norvegicus 15378 R-RNO-193816 https://reactome.org/PathwayBrowser/#/R-RNO-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Rattus norvegicus 15378 R-RNO-193821 https://reactome.org/PathwayBrowser/#/R-RNO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Rattus norvegicus 15378 R-RNO-193824 https://reactome.org/PathwayBrowser/#/R-RNO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Rattus norvegicus 15378 R-RNO-193841 https://reactome.org/PathwayBrowser/#/R-RNO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Rattus norvegicus 15378 R-RNO-193845 https://reactome.org/PathwayBrowser/#/R-RNO-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Rattus norvegicus 15378 R-RNO-193964 https://reactome.org/PathwayBrowser/#/R-RNO-193964 CYP21A2 21-hydroxylates PROG IEA Rattus norvegicus 15378 R-RNO-193965 https://reactome.org/PathwayBrowser/#/R-RNO-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Rattus norvegicus 15378 R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 15378 R-RNO-193995 https://reactome.org/PathwayBrowser/#/R-RNO-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Rattus norvegicus 15378 R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 15378 R-RNO-194017 https://reactome.org/PathwayBrowser/#/R-RNO-194017 CYP11B2 oxidises 11DCORST to CORST IEA Rattus norvegicus 15378 R-RNO-194023 https://reactome.org/PathwayBrowser/#/R-RNO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Rattus norvegicus 15378 R-RNO-194632 https://reactome.org/PathwayBrowser/#/R-RNO-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Rattus norvegicus 15378 R-RNO-194641 https://reactome.org/PathwayBrowser/#/R-RNO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15378 R-RNO-194642 https://reactome.org/PathwayBrowser/#/R-RNO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Rattus norvegicus 15378 R-RNO-194669 https://reactome.org/PathwayBrowser/#/R-RNO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15378 R-RNO-194674 https://reactome.org/PathwayBrowser/#/R-RNO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Rattus norvegicus 15378 R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 15378 R-RNO-194689 https://reactome.org/PathwayBrowser/#/R-RNO-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15378 R-RNO-194698 https://reactome.org/PathwayBrowser/#/R-RNO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Rattus norvegicus 15378 R-RNO-194718 https://reactome.org/PathwayBrowser/#/R-RNO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Rattus norvegicus 15378 R-RNO-195664 https://reactome.org/PathwayBrowser/#/R-RNO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Rattus norvegicus 15378 R-RNO-196060 https://reactome.org/PathwayBrowser/#/R-RNO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Rattus norvegicus 15378 R-RNO-196350 https://reactome.org/PathwayBrowser/#/R-RNO-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Rattus norvegicus 15378 R-RNO-196372 https://reactome.org/PathwayBrowser/#/R-RNO-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Rattus norvegicus 15378 R-RNO-196402 https://reactome.org/PathwayBrowser/#/R-RNO-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Rattus norvegicus 15378 R-RNO-196417 https://reactome.org/PathwayBrowser/#/R-RNO-196417 Reduction of desmosterol to cholesterol IEA Rattus norvegicus 15378 R-RNO-196753 https://reactome.org/PathwayBrowser/#/R-RNO-196753 2xPPCS ligates PPanK with Cys IEA Rattus norvegicus 15378 R-RNO-196754 https://reactome.org/PathwayBrowser/#/R-RNO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Rattus norvegicus 15378 R-RNO-196773 https://reactome.org/PathwayBrowser/#/R-RNO-196773 COASY phosphorylates DP-CoA IEA Rattus norvegicus 15378 R-RNO-196840 https://reactome.org/PathwayBrowser/#/R-RNO-196840 3xPPCDC:3FMN decarboxylates PPC IEA Rattus norvegicus 15378 R-RNO-196857 https://reactome.org/PathwayBrowser/#/R-RNO-196857 PANK2 phosphorylates PanK IEA Rattus norvegicus 15378 R-RNO-196929 https://reactome.org/PathwayBrowser/#/R-RNO-196929 FLAD1 phosphorylates FMN IEA Rattus norvegicus 15378 R-RNO-196955 https://reactome.org/PathwayBrowser/#/R-RNO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Rattus norvegicus 15378 R-RNO-196964 https://reactome.org/PathwayBrowser/#/R-RNO-196964 RFK:Mg2+ phosphorylates RIB IEA Rattus norvegicus 15378 R-RNO-197186 https://reactome.org/PathwayBrowser/#/R-RNO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Rattus norvegicus 15378 R-RNO-197268 https://reactome.org/PathwayBrowser/#/R-RNO-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Rattus norvegicus 15378 R-RNO-197963 https://reactome.org/PathwayBrowser/#/R-RNO-197963 DHFR2 reduces FOLA to DHF IEA Rattus norvegicus 15378 R-RNO-197972 https://reactome.org/PathwayBrowser/#/R-RNO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Rattus norvegicus 15378 R-RNO-198824 https://reactome.org/PathwayBrowser/#/R-RNO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Rattus norvegicus 15378 R-RNO-199203 https://reactome.org/PathwayBrowser/#/R-RNO-199203 PANK1/3 phosphorylate PanK IEA Rattus norvegicus 15378 R-RNO-200644 https://reactome.org/PathwayBrowser/#/R-RNO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Rattus norvegicus 15378 R-RNO-200676 https://reactome.org/PathwayBrowser/#/R-RNO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Rattus norvegicus 15378 R-RNO-200718 https://reactome.org/PathwayBrowser/#/R-RNO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Rattus norvegicus 15378 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 15378 R-RNO-204617 https://reactome.org/PathwayBrowser/#/R-RNO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Rattus norvegicus 15378 R-RNO-204647 https://reactome.org/PathwayBrowser/#/R-RNO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Rattus norvegicus 15378 R-RNO-204662 https://reactome.org/PathwayBrowser/#/R-RNO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Rattus norvegicus 15378 R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 15378 R-RNO-209772 https://reactome.org/PathwayBrowser/#/R-RNO-209772 Thyroxine is deiodinated to triiodothyronine IEA Rattus norvegicus 15378 R-RNO-209821 https://reactome.org/PathwayBrowser/#/R-RNO-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Rattus norvegicus 15378 R-RNO-209845 https://reactome.org/PathwayBrowser/#/R-RNO-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Rattus norvegicus 15378 R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 15378 R-RNO-209903 https://reactome.org/PathwayBrowser/#/R-RNO-209903 Noradrenaline is converted to adrenaline IEA Rattus norvegicus 15378 R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 15378 R-RNO-210404 https://reactome.org/PathwayBrowser/#/R-RNO-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Rattus norvegicus 15378 R-RNO-211873 https://reactome.org/PathwayBrowser/#/R-RNO-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Rattus norvegicus 15378 R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 15378 R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 15378 R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 15378 R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 15378 R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 15378 R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 15378 R-RNO-211923 https://reactome.org/PathwayBrowser/#/R-RNO-211923 CYP26C1 4-hydroxylates 9cRA IEA Rattus norvegicus 15378 R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 15378 R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 15378 R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 15378 R-RNO-211950 https://reactome.org/PathwayBrowser/#/R-RNO-211950 CYP24A1 24-hydroxylates CTL IEA Rattus norvegicus 15378 R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 15378 R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 15378 R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 15378 R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 15378 R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 15378 R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 15378 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 15378 R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 15378 R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 15378 R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 15378 R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 15378 R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 15378 R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15378 R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 15378 R-RNO-2161549 https://reactome.org/PathwayBrowser/#/R-RNO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Rattus norvegicus 15378 R-RNO-2161614 https://reactome.org/PathwayBrowser/#/R-RNO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Rattus norvegicus 15378 R-RNO-2161651 https://reactome.org/PathwayBrowser/#/R-RNO-2161651 PGE2 is converted to PGF2a by CBR1 IEA Rattus norvegicus 15378 R-RNO-2161745 https://reactome.org/PathwayBrowser/#/R-RNO-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15378 R-RNO-2161779 https://reactome.org/PathwayBrowser/#/R-RNO-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Rattus norvegicus 15378 R-RNO-2161792 https://reactome.org/PathwayBrowser/#/R-RNO-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15378 R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Rattus norvegicus 15378 R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 15378 R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus 15378 R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Rattus norvegicus 15378 R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 15378 R-RNO-2161951 https://reactome.org/PathwayBrowser/#/R-RNO-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Rattus norvegicus 15378 R-RNO-2162078 https://reactome.org/PathwayBrowser/#/R-RNO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Rattus norvegicus 15378 R-RNO-2162186 https://reactome.org/PathwayBrowser/#/R-RNO-2162186 COQ3 methylates DeMQ10H2 IEA Rattus norvegicus 15378 R-RNO-2162188 https://reactome.org/PathwayBrowser/#/R-RNO-2162188 COQ5 methylates MDMQ10H2 IEA Rattus norvegicus 15378 R-RNO-2162193 https://reactome.org/PathwayBrowser/#/R-RNO-2162193 COQ3 methylates DHDB IEA Rattus norvegicus 15378 R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 15378 R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 15378 R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 15378 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 15378 R-RNO-2395512 https://reactome.org/PathwayBrowser/#/R-RNO-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Rattus norvegicus 15378 R-RNO-2395517 https://reactome.org/PathwayBrowser/#/R-RNO-2395517 NADPH transfers electrons to FDXR IEA Rattus norvegicus 15378 R-RNO-2395818 https://reactome.org/PathwayBrowser/#/R-RNO-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Rattus norvegicus 15378 R-RNO-2395849 https://reactome.org/PathwayBrowser/#/R-RNO-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 15378 R-RNO-2395869 https://reactome.org/PathwayBrowser/#/R-RNO-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 15378 R-RNO-2395872 https://reactome.org/PathwayBrowser/#/R-RNO-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Rattus norvegicus 15378 R-RNO-2395873 https://reactome.org/PathwayBrowser/#/R-RNO-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Rattus norvegicus 15378 R-RNO-2395876 https://reactome.org/PathwayBrowser/#/R-RNO-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 15378 R-RNO-2395879 https://reactome.org/PathwayBrowser/#/R-RNO-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 15378 R-RNO-2395965 https://reactome.org/PathwayBrowser/#/R-RNO-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Rattus norvegicus 15378 R-RNO-2408514 https://reactome.org/PathwayBrowser/#/R-RNO-2408514 GSSeSG is reduced to GSSeH and GSH by Gsr TAS Rattus norvegicus 15378 R-RNO-2408553 https://reactome.org/PathwayBrowser/#/R-RNO-2408553 SeO3(2-) combines with GSH to form GSSeSG and GSSG TAS Rattus norvegicus 15378 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 15378 R-RNO-2464822 https://reactome.org/PathwayBrowser/#/R-RNO-2464822 RDH12 reduces atRAL to atROL IEA Rattus norvegicus 15378 R-RNO-2465940 https://reactome.org/PathwayBrowser/#/R-RNO-2465940 atRAL is reduced to atROL IEA Rattus norvegicus 15378 R-RNO-2509793 https://reactome.org/PathwayBrowser/#/R-RNO-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Rattus norvegicus 15378 R-RNO-2509816 https://reactome.org/PathwayBrowser/#/R-RNO-2509816 NUDT16 hydrolyses IDP to IMP IEA Rattus norvegicus 15378 R-RNO-2509827 https://reactome.org/PathwayBrowser/#/R-RNO-2509827 ITPA hydrolyses ITP to IMP IEA Rattus norvegicus 15378 R-RNO-2509831 https://reactome.org/PathwayBrowser/#/R-RNO-2509831 ITPA hydrolyses XTP to XMP IEA Rattus norvegicus 15378 R-RNO-2509838 https://reactome.org/PathwayBrowser/#/R-RNO-2509838 ITPA hydrolyses dITP to dIMP IEA Rattus norvegicus 15378 R-RNO-2534378 https://reactome.org/PathwayBrowser/#/R-RNO-2534378 Hv1 Mediated H+ Permeability IEA Rattus norvegicus 15378 R-RNO-264615 https://reactome.org/PathwayBrowser/#/R-RNO-264615 Loading of acetylcholine in synaptic vesicles IEA Rattus norvegicus 15378 R-RNO-2671885 https://reactome.org/PathwayBrowser/#/R-RNO-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Rattus norvegicus 15378 R-RNO-2730692 https://reactome.org/PathwayBrowser/#/R-RNO-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Rattus norvegicus 15378 R-RNO-2730959 https://reactome.org/PathwayBrowser/#/R-RNO-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Rattus norvegicus 15378 R-RNO-2855252 https://reactome.org/PathwayBrowser/#/R-RNO-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 15378 R-RNO-3095889 https://reactome.org/PathwayBrowser/#/R-RNO-3095889 MMACHC dealkylates RCbl IEA Rattus norvegicus 15378 R-RNO-3149518 https://reactome.org/PathwayBrowser/#/R-RNO-3149518 MTRR reduces cob(II)alamin to meCbl IEA Rattus norvegicus 15378 R-RNO-3149519 https://reactome.org/PathwayBrowser/#/R-RNO-3149519 MMACHC decyanates CNCbl IEA Rattus norvegicus 15378 R-RNO-3159253 https://reactome.org/PathwayBrowser/#/R-RNO-3159253 MMAB adenosylates cob(I)alamin IEA Rattus norvegicus 15378 R-RNO-3299680 https://reactome.org/PathwayBrowser/#/R-RNO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Rattus norvegicus 15378 R-RNO-3299682 https://reactome.org/PathwayBrowser/#/R-RNO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Rattus norvegicus 15378 R-RNO-3299691 https://reactome.org/PathwayBrowser/#/R-RNO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Rattus norvegicus 15378 R-RNO-3323050 https://reactome.org/PathwayBrowser/#/R-RNO-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Rattus norvegicus 15378 R-RNO-3323079 https://reactome.org/PathwayBrowser/#/R-RNO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 15378 R-RNO-350869 https://reactome.org/PathwayBrowser/#/R-RNO-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Rattus norvegicus 15378 R-RNO-350901 https://reactome.org/PathwayBrowser/#/R-RNO-350901 Iodide is organified IEA Rattus norvegicus 15378 R-RNO-352174 https://reactome.org/PathwayBrowser/#/R-RNO-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Rattus norvegicus 15378 R-RNO-352182 https://reactome.org/PathwayBrowser/#/R-RNO-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Rattus norvegicus 15378 R-RNO-372347 https://reactome.org/PathwayBrowser/#/R-RNO-372347 Cytosolic PYR is transported to the mitochondrial matrix TAS Rattus norvegicus 15378 R-RNO-372448 https://reactome.org/PathwayBrowser/#/R-RNO-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Rattus norvegicus 15378 R-RNO-373867 https://reactome.org/PathwayBrowser/#/R-RNO-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-RNO-373875 https://reactome.org/PathwayBrowser/#/R-RNO-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Rattus norvegicus 15378 R-RNO-375405 https://reactome.org/PathwayBrowser/#/R-RNO-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-RNO-375417 https://reactome.org/PathwayBrowser/#/R-RNO-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Rattus norvegicus 15378 R-RNO-3777112 https://reactome.org/PathwayBrowser/#/R-RNO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Rattus norvegicus 15378 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15378 R-RNO-380608 https://reactome.org/PathwayBrowser/#/R-RNO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Rattus norvegicus 15378 R-RNO-389540 https://reactome.org/PathwayBrowser/#/R-RNO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 15378 R-RNO-389550 https://reactome.org/PathwayBrowser/#/R-RNO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 15378 R-RNO-389609 https://reactome.org/PathwayBrowser/#/R-RNO-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Rattus norvegicus 15378 R-RNO-389826 https://reactome.org/PathwayBrowser/#/R-RNO-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Rattus norvegicus 15378 R-RNO-389995 https://reactome.org/PathwayBrowser/#/R-RNO-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Rattus norvegicus 15378 R-RNO-390251 https://reactome.org/PathwayBrowser/#/R-RNO-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 15378 R-RNO-390425 https://reactome.org/PathwayBrowser/#/R-RNO-390425 FAR1 reduces PalmCoA to HXOL IEA Rattus norvegicus 15378 R-RNO-390438 https://reactome.org/PathwayBrowser/#/R-RNO-390438 FAR2 reduces PalmCoA to HXOL IEA Rattus norvegicus 15378 R-RNO-418365 https://reactome.org/PathwayBrowser/#/R-RNO-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Rattus norvegicus 15378 R-RNO-425577 https://reactome.org/PathwayBrowser/#/R-RNO-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Rattus norvegicus 15378 R-RNO-425965 https://reactome.org/PathwayBrowser/#/R-RNO-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Rattus norvegicus 15378 R-RNO-425983 https://reactome.org/PathwayBrowser/#/R-RNO-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Rattus norvegicus 15378 R-RNO-425994 https://reactome.org/PathwayBrowser/#/R-RNO-425994 Na+/H+ exchanger transport (at cell membrane) IEA Rattus norvegicus 15378 R-RNO-426015 https://reactome.org/PathwayBrowser/#/R-RNO-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Rattus norvegicus 15378 R-RNO-426043 https://reactome.org/PathwayBrowser/#/R-RNO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Rattus norvegicus 15378 R-RNO-427555 https://reactome.org/PathwayBrowser/#/R-RNO-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-RNO-427910 https://reactome.org/PathwayBrowser/#/R-RNO-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Rattus norvegicus 15378 R-RNO-427998 https://reactome.org/PathwayBrowser/#/R-RNO-427998 Proton-coupled di- and tri-peptide cotransport IEA Rattus norvegicus 15378 R-RNO-428007 https://reactome.org/PathwayBrowser/#/R-RNO-428007 Proton-coupled histidine and di-peptide cotransport IEA Rattus norvegicus 15378 R-RNO-428015 https://reactome.org/PathwayBrowser/#/R-RNO-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-RNO-428052 https://reactome.org/PathwayBrowser/#/R-RNO-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Rattus norvegicus 15378 R-RNO-428123 https://reactome.org/PathwayBrowser/#/R-RNO-428123 KDSR reduces 3-ketosphingoid IEA Rattus norvegicus 15378 R-RNO-428127 https://reactome.org/PathwayBrowser/#/R-RNO-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Rattus norvegicus 15378 R-RNO-428185 https://reactome.org/PathwayBrowser/#/R-RNO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Rattus norvegicus 15378 R-RNO-428259 https://reactome.org/PathwayBrowser/#/R-RNO-428259 DEGS1 dehydrogenates dihydroceramide IEA Rattus norvegicus 15378 R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 15378 R-RNO-428273 https://reactome.org/PathwayBrowser/#/R-RNO-428273 SPHK1 phosphorylates sphingoid IEA Rattus norvegicus 15378 R-RNO-428625 https://reactome.org/PathwayBrowser/#/R-RNO-428625 Vesicular inhibitory amino acid transport IEA Rattus norvegicus 15378 R-RNO-429101 https://reactome.org/PathwayBrowser/#/R-RNO-429101 HMIT co-transports myo-inositol with a proton IEA Rattus norvegicus 15378 R-RNO-429157 https://reactome.org/PathwayBrowser/#/R-RNO-429157 ABCC4 accumulation of dense granule contents IEA Rattus norvegicus 15378 R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-RNO-434650 https://reactome.org/PathwayBrowser/#/R-RNO-434650 MATEs mediate extrusion of xenobiotics IEA Rattus norvegicus 15378 R-RNO-435171 https://reactome.org/PathwayBrowser/#/R-RNO-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Rattus norvegicus 15378 R-RNO-435349 https://reactome.org/PathwayBrowser/#/R-RNO-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-RNO-444393 https://reactome.org/PathwayBrowser/#/R-RNO-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Rattus norvegicus 15378 R-RNO-444419 https://reactome.org/PathwayBrowser/#/R-RNO-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Rattus norvegicus 15378 R-RNO-444731 https://reactome.org/PathwayBrowser/#/R-RNO-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Rattus norvegicus 15378 R-RNO-446277 https://reactome.org/PathwayBrowser/#/R-RNO-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Rattus norvegicus 15378 R-RNO-446278 https://reactome.org/PathwayBrowser/#/R-RNO-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Rattus norvegicus 15378 R-RNO-450971 https://reactome.org/PathwayBrowser/#/R-RNO-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Rattus norvegicus 15378 R-RNO-469659 https://reactome.org/PathwayBrowser/#/R-RNO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 15378 R-RNO-504054 https://reactome.org/PathwayBrowser/#/R-RNO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Rattus norvegicus 15378 R-RNO-508040 https://reactome.org/PathwayBrowser/#/R-RNO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Rattus norvegicus 15378 R-RNO-508369 https://reactome.org/PathwayBrowser/#/R-RNO-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Rattus norvegicus 15378 R-RNO-508473 https://reactome.org/PathwayBrowser/#/R-RNO-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Rattus norvegicus 15378 R-RNO-514604 https://reactome.org/PathwayBrowser/#/R-RNO-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Rattus norvegicus 15378 R-RNO-5218841 https://reactome.org/PathwayBrowser/#/R-RNO-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Rattus norvegicus 15378 R-RNO-5263614 https://reactome.org/PathwayBrowser/#/R-RNO-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Rattus norvegicus 15378 R-RNO-5263616 https://reactome.org/PathwayBrowser/#/R-RNO-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Rattus norvegicus 15378 R-RNO-5340130 https://reactome.org/PathwayBrowser/#/R-RNO-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Rattus norvegicus 15378 R-RNO-5340226 https://reactome.org/PathwayBrowser/#/R-RNO-5340226 CYGB dioxygenates NO IEA Rattus norvegicus 15378 R-RNO-5362518 https://reactome.org/PathwayBrowser/#/R-RNO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Rattus norvegicus 15378 R-RNO-5362522 https://reactome.org/PathwayBrowser/#/R-RNO-5362522 ALDHs oxidise atRAL to atRA IEA Rattus norvegicus 15378 R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 15378 R-RNO-5362564 https://reactome.org/PathwayBrowser/#/R-RNO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Rattus norvegicus 15378 R-RNO-5362721 https://reactome.org/PathwayBrowser/#/R-RNO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 15378 R-RNO-5419165 https://reactome.org/PathwayBrowser/#/R-RNO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Rattus norvegicus 15378 R-RNO-5423637 https://reactome.org/PathwayBrowser/#/R-RNO-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Rattus norvegicus 15378 R-RNO-5423647 https://reactome.org/PathwayBrowser/#/R-RNO-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Rattus norvegicus 15378 R-RNO-5423664 https://reactome.org/PathwayBrowser/#/R-RNO-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Rattus norvegicus 15378 R-RNO-5423672 https://reactome.org/PathwayBrowser/#/R-RNO-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Rattus norvegicus 15378 R-RNO-5423678 https://reactome.org/PathwayBrowser/#/R-RNO-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Rattus norvegicus 15378 R-RNO-548818 https://reactome.org/PathwayBrowser/#/R-RNO-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Rattus norvegicus 15378 R-RNO-548831 https://reactome.org/PathwayBrowser/#/R-RNO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Rattus norvegicus 15378 R-RNO-5615668 https://reactome.org/PathwayBrowser/#/R-RNO-5615668 AKR1C3 reduces atRAL to atROL IEA Rattus norvegicus 15378 R-RNO-5623643 https://reactome.org/PathwayBrowser/#/R-RNO-5623643 RDH13 reduces atRAL to atROL IEA Rattus norvegicus 15378 R-RNO-5652172 https://reactome.org/PathwayBrowser/#/R-RNO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Rattus norvegicus 15378 R-RNO-5652195 https://reactome.org/PathwayBrowser/#/R-RNO-5652195 SORD oxidizes D-sorbitol to Fru IEA Rattus norvegicus 15378 R-RNO-5661240 https://reactome.org/PathwayBrowser/#/R-RNO-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Rattus norvegicus 15378 R-RNO-5661256 https://reactome.org/PathwayBrowser/#/R-RNO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Rattus norvegicus 15378 R-RNO-5661290 https://reactome.org/PathwayBrowser/#/R-RNO-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Rattus norvegicus 15378 R-RNO-5662471 https://reactome.org/PathwayBrowser/#/R-RNO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Rattus norvegicus 15378 R-RNO-5662662 https://reactome.org/PathwayBrowser/#/R-RNO-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Rattus norvegicus 15378 R-RNO-5668629 https://reactome.org/PathwayBrowser/#/R-RNO-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Rattus norvegicus 15378 R-RNO-5668718 https://reactome.org/PathwayBrowser/#/R-RNO-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 15378 R-RNO-5668731 https://reactome.org/PathwayBrowser/#/R-RNO-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 15378 R-RNO-5678327 https://reactome.org/PathwayBrowser/#/R-RNO-5678327 MIOX oxidises Ins to GlcA IEA Rattus norvegicus 15378 R-RNO-5690565 https://reactome.org/PathwayBrowser/#/R-RNO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Rattus norvegicus 15378 R-RNO-5691107 https://reactome.org/PathwayBrowser/#/R-RNO-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Rattus norvegicus 15378 R-RNO-5692237 https://reactome.org/PathwayBrowser/#/R-RNO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Rattus norvegicus 15378 R-RNO-5692261 https://reactome.org/PathwayBrowser/#/R-RNO-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Rattus norvegicus 15378 R-RNO-5692283 https://reactome.org/PathwayBrowser/#/R-RNO-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Rattus norvegicus 15378 R-RNO-5693347 https://reactome.org/PathwayBrowser/#/R-RNO-5693347 CRYM reduces P2C to PPCA IEA Rattus norvegicus 15378 R-RNO-5693390 https://reactome.org/PathwayBrowser/#/R-RNO-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Rattus norvegicus 15378 R-RNO-5693681 https://reactome.org/PathwayBrowser/#/R-RNO-5693681 DUOX1,2 reduce O2 to H2O2 IEA Rattus norvegicus 15378 R-RNO-5693691 https://reactome.org/PathwayBrowser/#/R-RNO-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Rattus norvegicus 15378 R-RNO-5693761 https://reactome.org/PathwayBrowser/#/R-RNO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Rattus norvegicus 15378 R-RNO-5694018 https://reactome.org/PathwayBrowser/#/R-RNO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Rattus norvegicus 15378 R-RNO-5694462 https://reactome.org/PathwayBrowser/#/R-RNO-5694462 ABHD6,12 hydrolyse 3AG IEA Rattus norvegicus 15378 R-RNO-5696080 https://reactome.org/PathwayBrowser/#/R-RNO-5696080 ALDH3B1 oxidises HXAL to PALM IEA Rattus norvegicus 15378 R-RNO-5696091 https://reactome.org/PathwayBrowser/#/R-RNO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Rattus norvegicus 15378 R-RNO-5696101 https://reactome.org/PathwayBrowser/#/R-RNO-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Rattus norvegicus 15378 R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 15378 R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 15378 R-RNO-5696457 https://reactome.org/PathwayBrowser/#/R-RNO-5696457 BDH2 dehydrogenates 3HBA IEA Rattus norvegicus 15378 R-RNO-5696822 https://reactome.org/PathwayBrowser/#/R-RNO-5696822 AKR1B15 reduces EST17b to E1 IEA Rattus norvegicus 15378 R-RNO-5696838 https://reactome.org/PathwayBrowser/#/R-RNO-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Rattus norvegicus 15378 R-RNO-597628 https://reactome.org/PathwayBrowser/#/R-RNO-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Rattus norvegicus 15378 R-RNO-6783221 https://reactome.org/PathwayBrowser/#/R-RNO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Rattus norvegicus 15378 R-RNO-6783939 https://reactome.org/PathwayBrowser/#/R-RNO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 15378 R-RNO-6783955 https://reactome.org/PathwayBrowser/#/R-RNO-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 15378 R-RNO-6784399 https://reactome.org/PathwayBrowser/#/R-RNO-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Rattus norvegicus 15378 R-RNO-6785933 https://reactome.org/PathwayBrowser/#/R-RNO-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Rattus norvegicus 15378 R-RNO-6786239 https://reactome.org/PathwayBrowser/#/R-RNO-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Rattus norvegicus 15378 R-RNO-6786720 https://reactome.org/PathwayBrowser/#/R-RNO-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Rattus norvegicus 15378 R-RNO-6787642 https://reactome.org/PathwayBrowser/#/R-RNO-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Rattus norvegicus 15378 R-RNO-6788999 https://reactome.org/PathwayBrowser/#/R-RNO-6788999 HV1-mediated H+ transfer IEA Rattus norvegicus 15378 R-RNO-6789031 https://reactome.org/PathwayBrowser/#/R-RNO-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 15378 R-RNO-6789092 https://reactome.org/PathwayBrowser/#/R-RNO-6789092 NOX2 generates superoxide anion from oxygen IEA Rattus norvegicus 15378 R-RNO-6789126 https://reactome.org/PathwayBrowser/#/R-RNO-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 15378 R-RNO-6793590 https://reactome.org/PathwayBrowser/#/R-RNO-6793590 LIPT2 transfers octanoyl group to GCSH IEA Rattus norvegicus 15378 R-RNO-6793591 https://reactome.org/PathwayBrowser/#/R-RNO-6793591 LIAS synthesizes lipoyl-GCSH IEA Rattus norvegicus 15378 R-RNO-6799495 https://reactome.org/PathwayBrowser/#/R-RNO-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Rattus norvegicus 15378 R-RNO-6801342 https://reactome.org/PathwayBrowser/#/R-RNO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Rattus norvegicus 15378 R-RNO-6803771 https://reactome.org/PathwayBrowser/#/R-RNO-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Rattus norvegicus 15378 R-RNO-6806647 https://reactome.org/PathwayBrowser/#/R-RNO-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 15378 R-RNO-6806831 https://reactome.org/PathwayBrowser/#/R-RNO-6806831 CYB5Rs reduce MetHb to HbA IEA Rattus norvegicus 15378 R-RNO-6806967 https://reactome.org/PathwayBrowser/#/R-RNO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Rattus norvegicus 15378 R-RNO-6807053 https://reactome.org/PathwayBrowser/#/R-RNO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Rattus norvegicus 15378 R-RNO-6807055 https://reactome.org/PathwayBrowser/#/R-RNO-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Rattus norvegicus 15378 R-RNO-6807064 https://reactome.org/PathwayBrowser/#/R-RNO-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Rattus norvegicus 15378 R-RNO-6807557 https://reactome.org/PathwayBrowser/#/R-RNO-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Rattus norvegicus 15378 R-RNO-6807826 https://reactome.org/PathwayBrowser/#/R-RNO-6807826 LDHAL6B reduces PYR to LACT IEA Rattus norvegicus 15378 R-RNO-6808464 https://reactome.org/PathwayBrowser/#/R-RNO-6808464 ALDH3B2 oxidises HXAL to PALM IEA Rattus norvegicus 15378 R-RNO-6808487 https://reactome.org/PathwayBrowser/#/R-RNO-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 15378 R-RNO-6808496 https://reactome.org/PathwayBrowser/#/R-RNO-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 15378 R-RNO-6809264 https://reactome.org/PathwayBrowser/#/R-RNO-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 15378 R-RNO-6809287 https://reactome.org/PathwayBrowser/#/R-RNO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Rattus norvegicus 15378 R-RNO-6809810 https://reactome.org/PathwayBrowser/#/R-RNO-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Rattus norvegicus 15378 R-RNO-6810594 https://reactome.org/PathwayBrowser/#/R-RNO-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 15378 R-RNO-6813749 https://reactome.org/PathwayBrowser/#/R-RNO-6813749 ALDH1A1 oxidises GA to DGA IEA Rattus norvegicus 15378 R-RNO-6814153 https://reactome.org/PathwayBrowser/#/R-RNO-6814153 ADO oxidises 2AET to HTAU IEA Rattus norvegicus 15378 R-RNO-70333 https://reactome.org/PathwayBrowser/#/R-RNO-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Rattus norvegicus 15378 R-RNO-70377 https://reactome.org/PathwayBrowser/#/R-RNO-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Rattus norvegicus 15378 R-RNO-70420 https://reactome.org/PathwayBrowser/#/R-RNO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Rattus norvegicus 15378 R-RNO-70449 https://reactome.org/PathwayBrowser/#/R-RNO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Rattus norvegicus 15378 R-RNO-70467 https://reactome.org/PathwayBrowser/#/R-RNO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Rattus norvegicus 15378 R-RNO-70482 https://reactome.org/PathwayBrowser/#/R-RNO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Rattus norvegicus 15378 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 15378 R-RNO-70510 https://reactome.org/PathwayBrowser/#/R-RNO-70510 LDH tetramer oxidises LACT to PYR IEA Rattus norvegicus 15378 R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Rattus norvegicus 15378 R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Rattus norvegicus 15378 R-RNO-70664 https://reactome.org/PathwayBrowser/#/R-RNO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 15378 R-RNO-70670 https://reactome.org/PathwayBrowser/#/R-RNO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Rattus norvegicus 15378 R-RNO-70679 https://reactome.org/PathwayBrowser/#/R-RNO-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Rattus norvegicus 15378 R-RNO-70837 https://reactome.org/PathwayBrowser/#/R-RNO-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Rattus norvegicus 15378 R-RNO-70885 https://reactome.org/PathwayBrowser/#/R-RNO-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Rattus norvegicus 15378 R-RNO-70893 https://reactome.org/PathwayBrowser/#/R-RNO-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 15378 R-RNO-70906 https://reactome.org/PathwayBrowser/#/R-RNO-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Rattus norvegicus 15378 R-RNO-70938 https://reactome.org/PathwayBrowser/#/R-RNO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Rattus norvegicus 15378 R-RNO-70940 https://reactome.org/PathwayBrowser/#/R-RNO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Rattus norvegicus 15378 R-RNO-70941 https://reactome.org/PathwayBrowser/#/R-RNO-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Rattus norvegicus 15378 R-RNO-70975 https://reactome.org/PathwayBrowser/#/R-RNO-70975 CS acetylates OA to citrate IEA Rattus norvegicus 15378 R-RNO-70979 https://reactome.org/PathwayBrowser/#/R-RNO-70979 MDH2 dimer dehydrogenates MAL IEA Rattus norvegicus 15378 R-RNO-71130 https://reactome.org/PathwayBrowser/#/R-RNO-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Rattus norvegicus 15378 R-RNO-71164 https://reactome.org/PathwayBrowser/#/R-RNO-71164 HGD dioxygenates homogentisate IEA Rattus norvegicus 15378 R-RNO-71181 https://reactome.org/PathwayBrowser/#/R-RNO-71181 FAH cleaves 4FAA IEA Rattus norvegicus 15378 R-RNO-71200 https://reactome.org/PathwayBrowser/#/R-RNO-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Rattus norvegicus 15378 R-RNO-71260 https://reactome.org/PathwayBrowser/#/R-RNO-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Rattus norvegicus 15378 R-RNO-71286 https://reactome.org/PathwayBrowser/#/R-RNO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Rattus norvegicus 15378 R-RNO-71299 https://reactome.org/PathwayBrowser/#/R-RNO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Rattus norvegicus 15378 R-RNO-71401 https://reactome.org/PathwayBrowser/#/R-RNO-71401 OGDH dimer decarboxylates 2-OG IEA Rattus norvegicus 15378 R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 15378 R-RNO-71682 https://reactome.org/PathwayBrowser/#/R-RNO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 15378 R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 15378 R-RNO-71707 https://reactome.org/PathwayBrowser/#/R-RNO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Rattus norvegicus 15378 R-RNO-71723 https://reactome.org/PathwayBrowser/#/R-RNO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Rattus norvegicus 15378 R-RNO-71849 https://reactome.org/PathwayBrowser/#/R-RNO-71849 LDH tetramer reduces PYR to LACT IEA Rattus norvegicus 15378 R-RNO-73564 https://reactome.org/PathwayBrowser/#/R-RNO-73564 UMPS dimer decarboxylates OMP to UMP IEA Rattus norvegicus 15378 R-RNO-73571 https://reactome.org/PathwayBrowser/#/R-RNO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Rattus norvegicus 15378 R-RNO-73573 https://reactome.org/PathwayBrowser/#/R-RNO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Rattus norvegicus 15378 R-RNO-73577 https://reactome.org/PathwayBrowser/#/R-RNO-73577 CAD hexamer transforms L-Gln to CAP IEA Rattus norvegicus 15378 R-RNO-73585 https://reactome.org/PathwayBrowser/#/R-RNO-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Rattus norvegicus 15378 R-RNO-73589 https://reactome.org/PathwayBrowser/#/R-RNO-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Rattus norvegicus 15378 R-RNO-73591 https://reactome.org/PathwayBrowser/#/R-RNO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Rattus norvegicus 15378 R-RNO-73596 https://reactome.org/PathwayBrowser/#/R-RNO-73596 dCMP + H2O => dUMP + NH4+ IEA Rattus norvegicus 15378 R-RNO-73616 https://reactome.org/PathwayBrowser/#/R-RNO-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Rattus norvegicus 15378 R-RNO-73618 https://reactome.org/PathwayBrowser/#/R-RNO-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Rattus norvegicus 15378 R-RNO-73620 https://reactome.org/PathwayBrowser/#/R-RNO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Rattus norvegicus 15378 R-RNO-73646 https://reactome.org/PathwayBrowser/#/R-RNO-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Rattus norvegicus 15378 R-RNO-73647 https://reactome.org/PathwayBrowser/#/R-RNO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Rattus norvegicus 15378 R-RNO-73666 https://reactome.org/PathwayBrowser/#/R-RNO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Rattus norvegicus 15378 R-RNO-73792 https://reactome.org/PathwayBrowser/#/R-RNO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Rattus norvegicus 15378 R-RNO-73794 https://reactome.org/PathwayBrowser/#/R-RNO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Rattus norvegicus 15378 R-RNO-73805 https://reactome.org/PathwayBrowser/#/R-RNO-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Rattus norvegicus 15378 R-RNO-73806 https://reactome.org/PathwayBrowser/#/R-RNO-73806 AIR + CO2 => CAIR IEA Rattus norvegicus 15378 R-RNO-73810 https://reactome.org/PathwayBrowser/#/R-RNO-73810 FGAM + ATP => AIR + ADP + Pi IEA Rattus norvegicus 15378 R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 15378 R-RNO-73813 https://reactome.org/PathwayBrowser/#/R-RNO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Rattus norvegicus 15378 R-RNO-73814 https://reactome.org/PathwayBrowser/#/R-RNO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Rattus norvegicus 15378 R-RNO-73912 https://reactome.org/PathwayBrowser/#/R-RNO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Rattus norvegicus 15378 R-RNO-73920 https://reactome.org/PathwayBrowser/#/R-RNO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Rattus norvegicus 15378 R-RNO-74255 https://reactome.org/PathwayBrowser/#/R-RNO-74255 Guanine + H2O => Xanthine + NH4+ IEA Rattus norvegicus 15378 R-RNO-74723 https://reactome.org/PathwayBrowser/#/R-RNO-74723 Endosome acidification IEA Rattus norvegicus 15378 R-RNO-74872 https://reactome.org/PathwayBrowser/#/R-RNO-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 15378 R-RNO-75872 https://reactome.org/PathwayBrowser/#/R-RNO-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Rattus norvegicus 15378 R-RNO-75883 https://reactome.org/PathwayBrowser/#/R-RNO-75883 DHRS7B reduces GO3P to HXDG3P IEA Rattus norvegicus 15378 R-RNO-75889 https://reactome.org/PathwayBrowser/#/R-RNO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Rattus norvegicus 15378 R-RNO-76354 https://reactome.org/PathwayBrowser/#/R-RNO-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Rattus norvegicus 15378 R-RNO-76373 https://reactome.org/PathwayBrowser/#/R-RNO-76373 N-hydroxylation of 4-aminobiphenyl IEA Rattus norvegicus 15378 R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 15378 R-RNO-76416 https://reactome.org/PathwayBrowser/#/R-RNO-76416 Benzene is hydroxylated to phenol IEA Rattus norvegicus 15378 R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 15378 R-RNO-76453 https://reactome.org/PathwayBrowser/#/R-RNO-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Rattus norvegicus 15378 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 15378 R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 15378 R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 15378 R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 15378 R-RNO-77254 https://reactome.org/PathwayBrowser/#/R-RNO-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-RNO-77283 https://reactome.org/PathwayBrowser/#/R-RNO-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-RNO-77303 https://reactome.org/PathwayBrowser/#/R-RNO-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-RNO-77312 https://reactome.org/PathwayBrowser/#/R-RNO-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-RNO-77323 https://reactome.org/PathwayBrowser/#/R-RNO-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-RNO-77331 https://reactome.org/PathwayBrowser/#/R-RNO-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-RNO-77342 https://reactome.org/PathwayBrowser/#/R-RNO-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-RNO-804969 https://reactome.org/PathwayBrowser/#/R-RNO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Rattus norvegicus 15378 R-RNO-8849638 https://reactome.org/PathwayBrowser/#/R-RNO-8849638 Dissociation of the SPINK5:KLK5 complex at low pH IEA Rattus norvegicus 15378 R-RNO-8850846 https://reactome.org/PathwayBrowser/#/R-RNO-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-RNO-8850854 https://reactome.org/PathwayBrowser/#/R-RNO-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-RNO-8851110 https://reactome.org/PathwayBrowser/#/R-RNO-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-RNO-8851129 https://reactome.org/PathwayBrowser/#/R-RNO-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 15378 R-RNO-8862137 https://reactome.org/PathwayBrowser/#/R-RNO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 15378 R-RNO-8862152 https://reactome.org/PathwayBrowser/#/R-RNO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Rattus norvegicus 15378 R-RNO-8863494 https://reactome.org/PathwayBrowser/#/R-RNO-8863494 ASICs bind STOML3, (STOM) IEA Rattus norvegicus 15378 R-RNO-8866601 https://reactome.org/PathwayBrowser/#/R-RNO-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Rattus norvegicus 15378 R-RNO-8869606 https://reactome.org/PathwayBrowser/#/R-RNO-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Rattus norvegicus 15378 R-RNO-8869633 https://reactome.org/PathwayBrowser/#/R-RNO-8869633 NMRK1 phosphorylates NR to yield NMN IEA Rattus norvegicus 15378 R-RNO-8870346 https://reactome.org/PathwayBrowser/#/R-RNO-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Rattus norvegicus 15378 R-RNO-8875623 https://reactome.org/PathwayBrowser/#/R-RNO-8875623 SLC25A18,22 import L-Glu, H+ IEA Rattus norvegicus 15378 R-RNO-8878914 https://reactome.org/PathwayBrowser/#/R-RNO-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Rattus norvegicus 15378 R-RNO-888548 https://reactome.org/PathwayBrowser/#/R-RNO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Rattus norvegicus 15378 R-RNO-888572 https://reactome.org/PathwayBrowser/#/R-RNO-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Rattus norvegicus 15378 R-RNO-888577 https://reactome.org/PathwayBrowser/#/R-RNO-888577 Synthesis of GABA by GAD2 IEA Rattus norvegicus 15378 R-RNO-8933635 https://reactome.org/PathwayBrowser/#/R-RNO-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Rattus norvegicus 15378 R-RNO-8936442 https://reactome.org/PathwayBrowser/#/R-RNO-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Rattus norvegicus 15378 R-RNO-8938076 https://reactome.org/PathwayBrowser/#/R-RNO-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Rattus norvegicus 15378 R-RNO-8952873 https://reactome.org/PathwayBrowser/#/R-RNO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Rattus norvegicus 15378 R-RNO-8954468 https://reactome.org/PathwayBrowser/#/R-RNO-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Rattus norvegicus 15378 R-RNO-8955030 https://reactome.org/PathwayBrowser/#/R-RNO-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 15378 R-RNO-8955760 https://reactome.org/PathwayBrowser/#/R-RNO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Rattus norvegicus 15378 R-RNO-8956458 https://reactome.org/PathwayBrowser/#/R-RNO-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Rattus norvegicus 15378 R-RNO-8959510 https://reactome.org/PathwayBrowser/#/R-RNO-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Rattus norvegicus 15378 R-RNO-8959719 https://reactome.org/PathwayBrowser/#/R-RNO-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Rattus norvegicus 15378 R-RNO-9009950 https://reactome.org/PathwayBrowser/#/R-RNO-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Rattus norvegicus 15378 R-RNO-9011595 https://reactome.org/PathwayBrowser/#/R-RNO-9011595 GSTZ1 dimer dehalogenates DCA IEA Rattus norvegicus 15378 R-RNO-9012016 https://reactome.org/PathwayBrowser/#/R-RNO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Rattus norvegicus 15378 R-RNO-9012036 https://reactome.org/PathwayBrowser/#/R-RNO-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 15378 R-RNO-9024993 https://reactome.org/PathwayBrowser/#/R-RNO-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Rattus norvegicus 15378 R-RNO-9027043 https://reactome.org/PathwayBrowser/#/R-RNO-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Rattus norvegicus 15378 R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 15378 R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 15378 R-RNO-9037761 https://reactome.org/PathwayBrowser/#/R-RNO-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Rattus norvegicus 15378 R-RNO-917811 https://reactome.org/PathwayBrowser/#/R-RNO-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Rattus norvegicus 15378 R-RNO-917841 https://reactome.org/PathwayBrowser/#/R-RNO-917841 Acidification of Tf:TfR1 containing endosome IEA Rattus norvegicus 15378 R-RNO-917891 https://reactome.org/PathwayBrowser/#/R-RNO-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Rattus norvegicus 15378 R-RNO-917933 https://reactome.org/PathwayBrowser/#/R-RNO-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Rattus norvegicus 15378 R-RNO-917979 https://reactome.org/PathwayBrowser/#/R-RNO-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Rattus norvegicus 15378 R-RNO-937311 https://reactome.org/PathwayBrowser/#/R-RNO-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 15378 R-RNO-9620103 https://reactome.org/PathwayBrowser/#/R-RNO-9620103 ALDH2 transforms GTN to NO IEA Rattus norvegicus 15378 R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-RNO-9650165 https://reactome.org/PathwayBrowser/#/R-RNO-9650165 ASIC trimers bind H+ IEA Rattus norvegicus 15378 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 15378 R-RNO-9705713 https://reactome.org/PathwayBrowser/#/R-RNO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 15378 R-RNO-9705714 https://reactome.org/PathwayBrowser/#/R-RNO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 15378 R-RNO-9709098 https://reactome.org/PathwayBrowser/#/R-RNO-9709098 DHFR dimer reduces FOLA to DHF IEA Rattus norvegicus 15378 R-RNO-9727198 https://reactome.org/PathwayBrowser/#/R-RNO-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 15378 R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 15378 R-RNO-9727349 https://reactome.org/PathwayBrowser/#/R-RNO-9727349 XDH dehydrogenates xanthine to form urate IEA Rattus norvegicus 15378 R-RNO-9731228 https://reactome.org/PathwayBrowser/#/R-RNO-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Rattus norvegicus 15378 R-RNO-9731590 https://reactome.org/PathwayBrowser/#/R-RNO-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Rattus norvegicus 15378 R-RNO-9731613 https://reactome.org/PathwayBrowser/#/R-RNO-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Rattus norvegicus 15378 R-RNO-9731632 https://reactome.org/PathwayBrowser/#/R-RNO-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Rattus norvegicus 15378 R-RNO-9748945 https://reactome.org/PathwayBrowser/#/R-RNO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Rattus norvegicus 15378 R-RNO-9748957 https://reactome.org/PathwayBrowser/#/R-RNO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Rattus norvegicus 15378 R-RNO-9748979 https://reactome.org/PathwayBrowser/#/R-RNO-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Rattus norvegicus 15378 R-RNO-9748983 https://reactome.org/PathwayBrowser/#/R-RNO-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Rattus norvegicus 15378 R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 15378 R-RNO-9749609 https://reactome.org/PathwayBrowser/#/R-RNO-9749609 BCHE hydrolyzes ASA- IEA Rattus norvegicus 15378 R-RNO-9749647 https://reactome.org/PathwayBrowser/#/R-RNO-9749647 CES2 hydrolyzes ASA- IEA Rattus norvegicus 15378 R-RNO-9749792 https://reactome.org/PathwayBrowser/#/R-RNO-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Rattus norvegicus 15378 R-RNO-9753285 https://reactome.org/PathwayBrowser/#/R-RNO-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Rattus norvegicus 15378 R-RNO-9755937 https://reactome.org/PathwayBrowser/#/R-RNO-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Rattus norvegicus 15378 R-RNO-9756134 https://reactome.org/PathwayBrowser/#/R-RNO-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Rattus norvegicus 15378 R-RNO-9756138 https://reactome.org/PathwayBrowser/#/R-RNO-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Rattus norvegicus 15378 R-RNO-9756156 https://reactome.org/PathwayBrowser/#/R-RNO-9756156 UGT1A3 lactonizes ATV to ATVL IEA Rattus norvegicus 15378 R-RNO-9756162 https://reactome.org/PathwayBrowser/#/R-RNO-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Rattus norvegicus 15378 R-RNO-9756169 https://reactome.org/PathwayBrowser/#/R-RNO-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Rattus norvegicus 15378 R-RNO-9756177 https://reactome.org/PathwayBrowser/#/R-RNO-9756177 PON1,3 hydrolyse ATVL to ATV IEA Rattus norvegicus 15378 R-RNO-9756180 https://reactome.org/PathwayBrowser/#/R-RNO-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Rattus norvegicus 15378 R-RNO-9756183 https://reactome.org/PathwayBrowser/#/R-RNO-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Rattus norvegicus 15378 R-RNO-975629 https://reactome.org/PathwayBrowser/#/R-RNO-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 15378 R-RNO-9757706 https://reactome.org/PathwayBrowser/#/R-RNO-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Rattus norvegicus 15378 R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 15378 R-RNO-9758674 https://reactome.org/PathwayBrowser/#/R-RNO-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Rattus norvegicus 15378 R-RNO-9758682 https://reactome.org/PathwayBrowser/#/R-RNO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Rattus norvegicus 15378 R-RNO-9759259 https://reactome.org/PathwayBrowser/#/R-RNO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Rattus norvegicus 15378 R-RNO-9759549 https://reactome.org/PathwayBrowser/#/R-RNO-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Rattus norvegicus 15378 R-RNO-9760094 https://reactome.org/PathwayBrowser/#/R-RNO-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Rattus norvegicus 15378 R-RNO-977348 https://reactome.org/PathwayBrowser/#/R-RNO-977348 PHGDH tetramer dehydrogenates 3PG IEA Rattus norvegicus 15378 R-RNO-9794270 https://reactome.org/PathwayBrowser/#/R-RNO-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Rattus norvegicus 15378 R-RNO-9837337 https://reactome.org/PathwayBrowser/#/R-RNO-9837337 DCAKD phosphorylates DP-CoA IEA Rattus norvegicus 15378 R-RNO-9843721 https://reactome.org/PathwayBrowser/#/R-RNO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Rattus norvegicus 15378 R-RNO-9844587 https://reactome.org/PathwayBrowser/#/R-RNO-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Rattus norvegicus 15378 R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 15378 R-RNO-9845516 https://reactome.org/PathwayBrowser/#/R-RNO-9845516 B3GALT4 transfers Gal to gangliosides IEA Rattus norvegicus 15378 R-RNO-9845538 https://reactome.org/PathwayBrowser/#/R-RNO-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Rattus norvegicus 15378 R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 15378 R-RNO-9846305 https://reactome.org/PathwayBrowser/#/R-RNO-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Rattus norvegicus 15378 R-RNO-9846332 https://reactome.org/PathwayBrowser/#/R-RNO-9846332 FUT1,2 transfer fucose to gangliosides IEA Rattus norvegicus 15378 R-RNO-9846477 https://reactome.org/PathwayBrowser/#/R-RNO-9846477 A4GALT transfers galactose to LacCer IEA Rattus norvegicus 15378 R-RNO-9846501 https://reactome.org/PathwayBrowser/#/R-RNO-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Rattus norvegicus 15378 R-RNO-9851347 https://reactome.org/PathwayBrowser/#/R-RNO-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Rattus norvegicus 15378 R-RNO-9853499 https://reactome.org/PathwayBrowser/#/R-RNO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 15378 R-RNO-9854415 https://reactome.org/PathwayBrowser/#/R-RNO-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Rattus norvegicus 15378 R-RNO-9856871 https://reactome.org/PathwayBrowser/#/R-RNO-9856871 MDH1 reduces OA IEA Rattus norvegicus 15378 R-RNO-9861616 https://reactome.org/PathwayBrowser/#/R-RNO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 15378 R-RNO-9861642 https://reactome.org/PathwayBrowser/#/R-RNO-9861642 NEK1 phosphorylates ME1 IEA Rattus norvegicus 15378 R-RNO-9861660 https://reactome.org/PathwayBrowser/#/R-RNO-9861660 ME1 tetramer decarboxylates OA to PYR IEA Rattus norvegicus 15378 R-RNO-9861734 https://reactome.org/PathwayBrowser/#/R-RNO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Rattus norvegicus 15378 R-SCE-111524 https://reactome.org/PathwayBrowser/#/R-SCE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Saccharomyces cerevisiae 15378 R-SCE-1222516 https://reactome.org/PathwayBrowser/#/R-SCE-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Saccharomyces cerevisiae 15378 R-SCE-1237129 https://reactome.org/PathwayBrowser/#/R-SCE-1237129 Acireductone is created IEA Saccharomyces cerevisiae 15378 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 15378 R-SCE-1606273 https://reactome.org/PathwayBrowser/#/R-SCE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Saccharomyces cerevisiae 15378 R-SCE-1640164 https://reactome.org/PathwayBrowser/#/R-SCE-1640164 ENPP7 hydrolyzes sphingomyelin IEA Saccharomyces cerevisiae 15378 R-SCE-164651 https://reactome.org/PathwayBrowser/#/R-SCE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Saccharomyces cerevisiae 15378 R-SCE-164834 https://reactome.org/PathwayBrowser/#/R-SCE-164834 Enzyme-bound ATP is released IEA Saccharomyces cerevisiae 15378 R-SCE-174389 https://reactome.org/PathwayBrowser/#/R-SCE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Saccharomyces cerevisiae 15378 R-SCE-174392 https://reactome.org/PathwayBrowser/#/R-SCE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Saccharomyces cerevisiae 15378 R-SCE-189421 https://reactome.org/PathwayBrowser/#/R-SCE-189421 CPO transforms COPRO3 to PPGEN9 IEA Saccharomyces cerevisiae 15378 R-SCE-189425 https://reactome.org/PathwayBrowser/#/R-SCE-189425 UROD decarboxylates URO3 to COPRO3 IEA Saccharomyces cerevisiae 15378 R-SCE-189439 https://reactome.org/PathwayBrowser/#/R-SCE-189439 ALAD condenses 2 dALAs to form PBG IEA Saccharomyces cerevisiae 15378 R-SCE-189442 https://reactome.org/PathwayBrowser/#/R-SCE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Saccharomyces cerevisiae 15378 R-SCE-189465 https://reactome.org/PathwayBrowser/#/R-SCE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Saccharomyces cerevisiae 15378 R-SCE-190182 https://reactome.org/PathwayBrowser/#/R-SCE-190182 UROD decarboxylates URO1 to COPRO1 IEA Saccharomyces cerevisiae 15378 R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 15378 R-SCE-191323 https://reactome.org/PathwayBrowser/#/R-SCE-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Saccharomyces cerevisiae 15378 R-SCE-191352 https://reactome.org/PathwayBrowser/#/R-SCE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Saccharomyces cerevisiae 15378 R-SCE-191402 https://reactome.org/PathwayBrowser/#/R-SCE-191402 Reduction of presqualene diphosphate to form squalene IEA Saccharomyces cerevisiae 15378 R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 15378 R-SCE-192033 https://reactome.org/PathwayBrowser/#/R-SCE-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Saccharomyces cerevisiae 15378 R-SCE-192036 https://reactome.org/PathwayBrowser/#/R-SCE-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Saccharomyces cerevisiae 15378 R-SCE-192067 https://reactome.org/PathwayBrowser/#/R-SCE-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Saccharomyces cerevisiae 15378 R-SCE-192160 https://reactome.org/PathwayBrowser/#/R-SCE-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Saccharomyces cerevisiae 15378 R-SCE-193746 https://reactome.org/PathwayBrowser/#/R-SCE-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Saccharomyces cerevisiae 15378 R-SCE-193755 https://reactome.org/PathwayBrowser/#/R-SCE-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Saccharomyces cerevisiae 15378 R-SCE-193758 https://reactome.org/PathwayBrowser/#/R-SCE-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Saccharomyces cerevisiae 15378 R-SCE-193781 https://reactome.org/PathwayBrowser/#/R-SCE-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Saccharomyces cerevisiae 15378 R-SCE-193800 https://reactome.org/PathwayBrowser/#/R-SCE-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Saccharomyces cerevisiae 15378 R-SCE-193821 https://reactome.org/PathwayBrowser/#/R-SCE-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Saccharomyces cerevisiae 15378 R-SCE-193824 https://reactome.org/PathwayBrowser/#/R-SCE-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Saccharomyces cerevisiae 15378 R-SCE-193841 https://reactome.org/PathwayBrowser/#/R-SCE-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Saccharomyces cerevisiae 15378 R-SCE-194641 https://reactome.org/PathwayBrowser/#/R-SCE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 15378 R-SCE-194642 https://reactome.org/PathwayBrowser/#/R-SCE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Saccharomyces cerevisiae 15378 R-SCE-194669 https://reactome.org/PathwayBrowser/#/R-SCE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 15378 R-SCE-194674 https://reactome.org/PathwayBrowser/#/R-SCE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Saccharomyces cerevisiae 15378 R-SCE-194678 https://reactome.org/PathwayBrowser/#/R-SCE-194678 CYP51A1 demethylates LNSOL IEA Saccharomyces cerevisiae 15378 R-SCE-194698 https://reactome.org/PathwayBrowser/#/R-SCE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Saccharomyces cerevisiae 15378 R-SCE-194718 https://reactome.org/PathwayBrowser/#/R-SCE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Saccharomyces cerevisiae 15378 R-SCE-195664 https://reactome.org/PathwayBrowser/#/R-SCE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Saccharomyces cerevisiae 15378 R-SCE-196060 https://reactome.org/PathwayBrowser/#/R-SCE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Saccharomyces cerevisiae 15378 R-SCE-196753 https://reactome.org/PathwayBrowser/#/R-SCE-196753 2xPPCS ligates PPanK with Cys IEA Saccharomyces cerevisiae 15378 R-SCE-196754 https://reactome.org/PathwayBrowser/#/R-SCE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Saccharomyces cerevisiae 15378 R-SCE-196773 https://reactome.org/PathwayBrowser/#/R-SCE-196773 COASY phosphorylates DP-CoA IEA Saccharomyces cerevisiae 15378 R-SCE-196840 https://reactome.org/PathwayBrowser/#/R-SCE-196840 3xPPCDC:3FMN decarboxylates PPC IEA Saccharomyces cerevisiae 15378 R-SCE-196929 https://reactome.org/PathwayBrowser/#/R-SCE-196929 FLAD1 phosphorylates FMN IEA Saccharomyces cerevisiae 15378 R-SCE-196955 https://reactome.org/PathwayBrowser/#/R-SCE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Saccharomyces cerevisiae 15378 R-SCE-196964 https://reactome.org/PathwayBrowser/#/R-SCE-196964 RFK:Mg2+ phosphorylates RIB IEA Saccharomyces cerevisiae 15378 R-SCE-197186 https://reactome.org/PathwayBrowser/#/R-SCE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Saccharomyces cerevisiae 15378 R-SCE-197268 https://reactome.org/PathwayBrowser/#/R-SCE-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Saccharomyces cerevisiae 15378 R-SCE-197963 https://reactome.org/PathwayBrowser/#/R-SCE-197963 DHFR2 reduces FOLA to DHF IEA Saccharomyces cerevisiae 15378 R-SCE-197972 https://reactome.org/PathwayBrowser/#/R-SCE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Saccharomyces cerevisiae 15378 R-SCE-198824 https://reactome.org/PathwayBrowser/#/R-SCE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Saccharomyces cerevisiae 15378 R-SCE-200644 https://reactome.org/PathwayBrowser/#/R-SCE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Saccharomyces cerevisiae 15378 R-SCE-200676 https://reactome.org/PathwayBrowser/#/R-SCE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Saccharomyces cerevisiae 15378 R-SCE-200718 https://reactome.org/PathwayBrowser/#/R-SCE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Saccharomyces cerevisiae 15378 R-SCE-204617 https://reactome.org/PathwayBrowser/#/R-SCE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Saccharomyces cerevisiae 15378 R-SCE-204647 https://reactome.org/PathwayBrowser/#/R-SCE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Saccharomyces cerevisiae 15378 R-SCE-204662 https://reactome.org/PathwayBrowser/#/R-SCE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Saccharomyces cerevisiae 15378 R-SCE-2161549 https://reactome.org/PathwayBrowser/#/R-SCE-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Saccharomyces cerevisiae 15378 R-SCE-2161614 https://reactome.org/PathwayBrowser/#/R-SCE-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Saccharomyces cerevisiae 15378 R-SCE-2162078 https://reactome.org/PathwayBrowser/#/R-SCE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Saccharomyces cerevisiae 15378 R-SCE-2162186 https://reactome.org/PathwayBrowser/#/R-SCE-2162186 COQ3 methylates DeMQ10H2 IEA Saccharomyces cerevisiae 15378 R-SCE-2162188 https://reactome.org/PathwayBrowser/#/R-SCE-2162188 COQ5 methylates MDMQ10H2 IEA Saccharomyces cerevisiae 15378 R-SCE-2162193 https://reactome.org/PathwayBrowser/#/R-SCE-2162193 COQ3 methylates DHDB IEA Saccharomyces cerevisiae 15378 R-SCE-2162194 https://reactome.org/PathwayBrowser/#/R-SCE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Saccharomyces cerevisiae 15378 R-SCE-2162292 https://reactome.org/PathwayBrowser/#/R-SCE-2162292 HHB is hydroxylated to DHHB by Coq6 TAS Saccharomyces cerevisiae 15378 R-SCE-2164813 https://reactome.org/PathwayBrowser/#/R-SCE-2164813 HMPhOH is hydroxylated to MDMQ6H2 by HMPhOH monooxygenase TAS Saccharomyces cerevisiae 15378 R-SCE-2164816 https://reactome.org/PathwayBrowser/#/R-SCE-2164816 MHHB is decarboxylated to HMPhOH by MHHB decarboxylase TAS Saccharomyces cerevisiae 15378 R-SCE-2395512 https://reactome.org/PathwayBrowser/#/R-SCE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Saccharomyces cerevisiae 15378 R-SCE-2395517 https://reactome.org/PathwayBrowser/#/R-SCE-2395517 NADPH transfers electrons to FDXR IEA Saccharomyces cerevisiae 15378 R-SCE-2408518 https://reactome.org/PathwayBrowser/#/R-SCE-2408518 PAPSe is reduced to SeO3(2-) by MET16 TAS Saccharomyces cerevisiae 15378 R-SCE-2465940 https://reactome.org/PathwayBrowser/#/R-SCE-2465940 atRAL is reduced to atROL IEA Saccharomyces cerevisiae 15378 R-SCE-2509827 https://reactome.org/PathwayBrowser/#/R-SCE-2509827 ITPA hydrolyses ITP to IMP IEA Saccharomyces cerevisiae 15378 R-SCE-2509831 https://reactome.org/PathwayBrowser/#/R-SCE-2509831 ITPA hydrolyses XTP to XMP IEA Saccharomyces cerevisiae 15378 R-SCE-2509838 https://reactome.org/PathwayBrowser/#/R-SCE-2509838 ITPA hydrolyses dITP to dIMP IEA Saccharomyces cerevisiae 15378 R-SCE-2564819 https://reactome.org/PathwayBrowser/#/R-SCE-2564819 NADPH reduces TAH18:DRE2 TAS Saccharomyces cerevisiae 15378 R-SCE-2730692 https://reactome.org/PathwayBrowser/#/R-SCE-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Saccharomyces cerevisiae 15378 R-SCE-3299680 https://reactome.org/PathwayBrowser/#/R-SCE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Saccharomyces cerevisiae 15378 R-SCE-3299682 https://reactome.org/PathwayBrowser/#/R-SCE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Saccharomyces cerevisiae 15378 R-SCE-3299691 https://reactome.org/PathwayBrowser/#/R-SCE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Saccharomyces cerevisiae 15378 R-SCE-3323079 https://reactome.org/PathwayBrowser/#/R-SCE-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 15378 R-SCE-352174 https://reactome.org/PathwayBrowser/#/R-SCE-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Saccharomyces cerevisiae 15378 R-SCE-352182 https://reactome.org/PathwayBrowser/#/R-SCE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Saccharomyces cerevisiae 15378 R-SCE-372448 https://reactome.org/PathwayBrowser/#/R-SCE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Saccharomyces cerevisiae 15378 R-SCE-375405 https://reactome.org/PathwayBrowser/#/R-SCE-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 15378 R-SCE-375417 https://reactome.org/PathwayBrowser/#/R-SCE-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Saccharomyces cerevisiae 15378 R-SCE-3777112 https://reactome.org/PathwayBrowser/#/R-SCE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Saccharomyces cerevisiae 15378 R-SCE-380608 https://reactome.org/PathwayBrowser/#/R-SCE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Saccharomyces cerevisiae 15378 R-SCE-389540 https://reactome.org/PathwayBrowser/#/R-SCE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 15378 R-SCE-389550 https://reactome.org/PathwayBrowser/#/R-SCE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 15378 R-SCE-389609 https://reactome.org/PathwayBrowser/#/R-SCE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Saccharomyces cerevisiae 15378 R-SCE-425965 https://reactome.org/PathwayBrowser/#/R-SCE-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Saccharomyces cerevisiae 15378 R-SCE-425983 https://reactome.org/PathwayBrowser/#/R-SCE-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Saccharomyces cerevisiae 15378 R-SCE-425994 https://reactome.org/PathwayBrowser/#/R-SCE-425994 Na+/H+ exchanger transport (at cell membrane) IEA Saccharomyces cerevisiae 15378 R-SCE-426015 https://reactome.org/PathwayBrowser/#/R-SCE-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Saccharomyces cerevisiae 15378 R-SCE-426043 https://reactome.org/PathwayBrowser/#/R-SCE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Saccharomyces cerevisiae 15378 R-SCE-427555 https://reactome.org/PathwayBrowser/#/R-SCE-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 15378 R-SCE-428007 https://reactome.org/PathwayBrowser/#/R-SCE-428007 Proton-coupled histidine and di-peptide cotransport IEA Saccharomyces cerevisiae 15378 R-SCE-428123 https://reactome.org/PathwayBrowser/#/R-SCE-428123 KDSR reduces 3-ketosphingoid IEA Saccharomyces cerevisiae 15378 R-SCE-428185 https://reactome.org/PathwayBrowser/#/R-SCE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Saccharomyces cerevisiae 15378 R-SCE-428273 https://reactome.org/PathwayBrowser/#/R-SCE-428273 SPHK1 phosphorylates sphingoid IEA Saccharomyces cerevisiae 15378 R-SCE-428625 https://reactome.org/PathwayBrowser/#/R-SCE-428625 Vesicular inhibitory amino acid transport IEA Saccharomyces cerevisiae 15378 R-SCE-429101 https://reactome.org/PathwayBrowser/#/R-SCE-429101 HMIT co-transports myo-inositol with a proton IEA Saccharomyces cerevisiae 15378 R-SCE-434650 https://reactome.org/PathwayBrowser/#/R-SCE-434650 MATEs mediate extrusion of xenobiotics IEA Saccharomyces cerevisiae 15378 R-SCE-504054 https://reactome.org/PathwayBrowser/#/R-SCE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Saccharomyces cerevisiae 15378 R-SCE-508040 https://reactome.org/PathwayBrowser/#/R-SCE-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Saccharomyces cerevisiae 15378 R-SCE-5340130 https://reactome.org/PathwayBrowser/#/R-SCE-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Saccharomyces cerevisiae 15378 R-SCE-5362518 https://reactome.org/PathwayBrowser/#/R-SCE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Saccharomyces cerevisiae 15378 R-SCE-5362522 https://reactome.org/PathwayBrowser/#/R-SCE-5362522 ALDHs oxidise atRAL to atRA IEA Saccharomyces cerevisiae 15378 R-SCE-5362564 https://reactome.org/PathwayBrowser/#/R-SCE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Saccharomyces cerevisiae 15378 R-SCE-5419165 https://reactome.org/PathwayBrowser/#/R-SCE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Saccharomyces cerevisiae 15378 R-SCE-548831 https://reactome.org/PathwayBrowser/#/R-SCE-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Saccharomyces cerevisiae 15378 R-SCE-5615668 https://reactome.org/PathwayBrowser/#/R-SCE-5615668 AKR1C3 reduces atRAL to atROL IEA Saccharomyces cerevisiae 15378 R-SCE-5652172 https://reactome.org/PathwayBrowser/#/R-SCE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Saccharomyces cerevisiae 15378 R-SCE-5652195 https://reactome.org/PathwayBrowser/#/R-SCE-5652195 SORD oxidizes D-sorbitol to Fru IEA Saccharomyces cerevisiae 15378 R-SCE-5661256 https://reactome.org/PathwayBrowser/#/R-SCE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Saccharomyces cerevisiae 15378 R-SCE-5662471 https://reactome.org/PathwayBrowser/#/R-SCE-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Saccharomyces cerevisiae 15378 R-SCE-5690565 https://reactome.org/PathwayBrowser/#/R-SCE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15378 R-SCE-5692237 https://reactome.org/PathwayBrowser/#/R-SCE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Saccharomyces cerevisiae 15378 R-SCE-5692261 https://reactome.org/PathwayBrowser/#/R-SCE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Saccharomyces cerevisiae 15378 R-SCE-5692283 https://reactome.org/PathwayBrowser/#/R-SCE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Saccharomyces cerevisiae 15378 R-SCE-5693347 https://reactome.org/PathwayBrowser/#/R-SCE-5693347 CRYM reduces P2C to PPCA IEA Saccharomyces cerevisiae 15378 R-SCE-5693390 https://reactome.org/PathwayBrowser/#/R-SCE-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Saccharomyces cerevisiae 15378 R-SCE-5693681 https://reactome.org/PathwayBrowser/#/R-SCE-5693681 DUOX1,2 reduce O2 to H2O2 IEA Saccharomyces cerevisiae 15378 R-SCE-5693761 https://reactome.org/PathwayBrowser/#/R-SCE-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Saccharomyces cerevisiae 15378 R-SCE-5694018 https://reactome.org/PathwayBrowser/#/R-SCE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Saccharomyces cerevisiae 15378 R-SCE-5694462 https://reactome.org/PathwayBrowser/#/R-SCE-5694462 ABHD6,12 hydrolyse 3AG IEA Saccharomyces cerevisiae 15378 R-SCE-5696080 https://reactome.org/PathwayBrowser/#/R-SCE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 15378 R-SCE-5696091 https://reactome.org/PathwayBrowser/#/R-SCE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Saccharomyces cerevisiae 15378 R-SCE-5696822 https://reactome.org/PathwayBrowser/#/R-SCE-5696822 AKR1B15 reduces EST17b to E1 IEA Saccharomyces cerevisiae 15378 R-SCE-6783221 https://reactome.org/PathwayBrowser/#/R-SCE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Saccharomyces cerevisiae 15378 R-SCE-6783939 https://reactome.org/PathwayBrowser/#/R-SCE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 15378 R-SCE-6783955 https://reactome.org/PathwayBrowser/#/R-SCE-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 15378 R-SCE-6786720 https://reactome.org/PathwayBrowser/#/R-SCE-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Saccharomyces cerevisiae 15378 R-SCE-6793590 https://reactome.org/PathwayBrowser/#/R-SCE-6793590 LIPT2 transfers octanoyl group to GCSH IEA Saccharomyces cerevisiae 15378 R-SCE-6801342 https://reactome.org/PathwayBrowser/#/R-SCE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Saccharomyces cerevisiae 15378 R-SCE-6806967 https://reactome.org/PathwayBrowser/#/R-SCE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Saccharomyces cerevisiae 15378 R-SCE-6807053 https://reactome.org/PathwayBrowser/#/R-SCE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Saccharomyces cerevisiae 15378 R-SCE-6807557 https://reactome.org/PathwayBrowser/#/R-SCE-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Saccharomyces cerevisiae 15378 R-SCE-6808464 https://reactome.org/PathwayBrowser/#/R-SCE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 15378 R-SCE-6809287 https://reactome.org/PathwayBrowser/#/R-SCE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Saccharomyces cerevisiae 15378 R-SCE-6813749 https://reactome.org/PathwayBrowser/#/R-SCE-6813749 ALDH1A1 oxidises GA to DGA IEA Saccharomyces cerevisiae 15378 R-SCE-70377 https://reactome.org/PathwayBrowser/#/R-SCE-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Saccharomyces cerevisiae 15378 R-SCE-70420 https://reactome.org/PathwayBrowser/#/R-SCE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Saccharomyces cerevisiae 15378 R-SCE-70449 https://reactome.org/PathwayBrowser/#/R-SCE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Saccharomyces cerevisiae 15378 R-SCE-70467 https://reactome.org/PathwayBrowser/#/R-SCE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 15378 R-SCE-70482 https://reactome.org/PathwayBrowser/#/R-SCE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Saccharomyces cerevisiae 15378 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 15378 R-SCE-70664 https://reactome.org/PathwayBrowser/#/R-SCE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 15378 R-SCE-70670 https://reactome.org/PathwayBrowser/#/R-SCE-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Saccharomyces cerevisiae 15378 R-SCE-70938 https://reactome.org/PathwayBrowser/#/R-SCE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Saccharomyces cerevisiae 15378 R-SCE-70940 https://reactome.org/PathwayBrowser/#/R-SCE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Saccharomyces cerevisiae 15378 R-SCE-70975 https://reactome.org/PathwayBrowser/#/R-SCE-70975 CS acetylates OA to citrate IEA Saccharomyces cerevisiae 15378 R-SCE-70979 https://reactome.org/PathwayBrowser/#/R-SCE-70979 MDH2 dimer dehydrogenates MAL IEA Saccharomyces cerevisiae 15378 R-SCE-71200 https://reactome.org/PathwayBrowser/#/R-SCE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Saccharomyces cerevisiae 15378 R-SCE-71286 https://reactome.org/PathwayBrowser/#/R-SCE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Saccharomyces cerevisiae 15378 R-SCE-71299 https://reactome.org/PathwayBrowser/#/R-SCE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 15378 R-SCE-71401 https://reactome.org/PathwayBrowser/#/R-SCE-71401 OGDH dimer decarboxylates 2-OG IEA Saccharomyces cerevisiae 15378 R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 15378 R-SCE-71682 https://reactome.org/PathwayBrowser/#/R-SCE-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 15378 R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 15378 R-SCE-71707 https://reactome.org/PathwayBrowser/#/R-SCE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Saccharomyces cerevisiae 15378 R-SCE-71723 https://reactome.org/PathwayBrowser/#/R-SCE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Saccharomyces cerevisiae 15378 R-SCE-73571 https://reactome.org/PathwayBrowser/#/R-SCE-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Saccharomyces cerevisiae 15378 R-SCE-73573 https://reactome.org/PathwayBrowser/#/R-SCE-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Saccharomyces cerevisiae 15378 R-SCE-73577 https://reactome.org/PathwayBrowser/#/R-SCE-73577 CAD hexamer transforms L-Gln to CAP IEA Saccharomyces cerevisiae 15378 R-SCE-73647 https://reactome.org/PathwayBrowser/#/R-SCE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Saccharomyces cerevisiae 15378 R-SCE-73666 https://reactome.org/PathwayBrowser/#/R-SCE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Saccharomyces cerevisiae 15378 R-SCE-73792 https://reactome.org/PathwayBrowser/#/R-SCE-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Saccharomyces cerevisiae 15378 R-SCE-73794 https://reactome.org/PathwayBrowser/#/R-SCE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Saccharomyces cerevisiae 15378 R-SCE-73810 https://reactome.org/PathwayBrowser/#/R-SCE-73810 FGAM + ATP => AIR + ADP + Pi IEA Saccharomyces cerevisiae 15378 R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 15378 R-SCE-73813 https://reactome.org/PathwayBrowser/#/R-SCE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Saccharomyces cerevisiae 15378 R-SCE-73814 https://reactome.org/PathwayBrowser/#/R-SCE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Saccharomyces cerevisiae 15378 R-SCE-74255 https://reactome.org/PathwayBrowser/#/R-SCE-74255 Guanine + H2O => Xanthine + NH4+ IEA Saccharomyces cerevisiae 15378 R-SCE-74723 https://reactome.org/PathwayBrowser/#/R-SCE-74723 Endosome acidification IEA Saccharomyces cerevisiae 15378 R-SCE-75889 https://reactome.org/PathwayBrowser/#/R-SCE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Saccharomyces cerevisiae 15378 R-SCE-8847579 https://reactome.org/PathwayBrowser/#/R-SCE-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15378 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15378 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 15378 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15378 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15378 R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 15378 R-SCE-8862152 https://reactome.org/PathwayBrowser/#/R-SCE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Saccharomyces cerevisiae 15378 R-SCE-8875623 https://reactome.org/PathwayBrowser/#/R-SCE-8875623 SLC25A18,22 import L-Glu, H+ IEA Saccharomyces cerevisiae 15378 R-SCE-888548 https://reactome.org/PathwayBrowser/#/R-SCE-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Saccharomyces cerevisiae 15378 R-SCE-8952873 https://reactome.org/PathwayBrowser/#/R-SCE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Saccharomyces cerevisiae 15378 R-SCE-8955760 https://reactome.org/PathwayBrowser/#/R-SCE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Saccharomyces cerevisiae 15378 R-SCE-9012016 https://reactome.org/PathwayBrowser/#/R-SCE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Saccharomyces cerevisiae 15378 R-SCE-917841 https://reactome.org/PathwayBrowser/#/R-SCE-917841 Acidification of Tf:TfR1 containing endosome IEA Saccharomyces cerevisiae 15378 R-SCE-917979 https://reactome.org/PathwayBrowser/#/R-SCE-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Saccharomyces cerevisiae 15378 R-SCE-9620103 https://reactome.org/PathwayBrowser/#/R-SCE-9620103 ALDH2 transforms GTN to NO IEA Saccharomyces cerevisiae 15378 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 15378 R-SCE-9705714 https://reactome.org/PathwayBrowser/#/R-SCE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Saccharomyces cerevisiae 15378 R-SCE-9709098 https://reactome.org/PathwayBrowser/#/R-SCE-9709098 DHFR dimer reduces FOLA to DHF IEA Saccharomyces cerevisiae 15378 R-SCE-9748945 https://reactome.org/PathwayBrowser/#/R-SCE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Saccharomyces cerevisiae 15378 R-SCE-9748957 https://reactome.org/PathwayBrowser/#/R-SCE-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Saccharomyces cerevisiae 15378 R-SCE-9758682 https://reactome.org/PathwayBrowser/#/R-SCE-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Saccharomyces cerevisiae 15378 R-SCE-9760094 https://reactome.org/PathwayBrowser/#/R-SCE-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Saccharomyces cerevisiae 15378 R-SCE-9837337 https://reactome.org/PathwayBrowser/#/R-SCE-9837337 DCAKD phosphorylates DP-CoA IEA Saccharomyces cerevisiae 15378 R-SCE-9843721 https://reactome.org/PathwayBrowser/#/R-SCE-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Saccharomyces cerevisiae 15378 R-SCE-9853499 https://reactome.org/PathwayBrowser/#/R-SCE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 15378 R-SCE-9861616 https://reactome.org/PathwayBrowser/#/R-SCE-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 15378 R-SCE-9861734 https://reactome.org/PathwayBrowser/#/R-SCE-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Saccharomyces cerevisiae 15378 R-SPO-111524 https://reactome.org/PathwayBrowser/#/R-SPO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Schizosaccharomyces pombe 15378 R-SPO-1222516 https://reactome.org/PathwayBrowser/#/R-SPO-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Schizosaccharomyces pombe 15378 R-SPO-1237129 https://reactome.org/PathwayBrowser/#/R-SPO-1237129 Acireductone is created IEA Schizosaccharomyces pombe 15378 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 15378 R-SPO-1606273 https://reactome.org/PathwayBrowser/#/R-SPO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Schizosaccharomyces pombe 15378 R-SPO-1640164 https://reactome.org/PathwayBrowser/#/R-SPO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Schizosaccharomyces pombe 15378 R-SPO-164651 https://reactome.org/PathwayBrowser/#/R-SPO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Schizosaccharomyces pombe 15378 R-SPO-174389 https://reactome.org/PathwayBrowser/#/R-SPO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Schizosaccharomyces pombe 15378 R-SPO-174392 https://reactome.org/PathwayBrowser/#/R-SPO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Schizosaccharomyces pombe 15378 R-SPO-189421 https://reactome.org/PathwayBrowser/#/R-SPO-189421 CPO transforms COPRO3 to PPGEN9 IEA Schizosaccharomyces pombe 15378 R-SPO-189425 https://reactome.org/PathwayBrowser/#/R-SPO-189425 UROD decarboxylates URO3 to COPRO3 IEA Schizosaccharomyces pombe 15378 R-SPO-189439 https://reactome.org/PathwayBrowser/#/R-SPO-189439 ALAD condenses 2 dALAs to form PBG IEA Schizosaccharomyces pombe 15378 R-SPO-189442 https://reactome.org/PathwayBrowser/#/R-SPO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Schizosaccharomyces pombe 15378 R-SPO-189465 https://reactome.org/PathwayBrowser/#/R-SPO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Schizosaccharomyces pombe 15378 R-SPO-190182 https://reactome.org/PathwayBrowser/#/R-SPO-190182 UROD decarboxylates URO1 to COPRO1 IEA Schizosaccharomyces pombe 15378 R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 15378 R-SPO-191323 https://reactome.org/PathwayBrowser/#/R-SPO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Schizosaccharomyces pombe 15378 R-SPO-191352 https://reactome.org/PathwayBrowser/#/R-SPO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Schizosaccharomyces pombe 15378 R-SPO-191402 https://reactome.org/PathwayBrowser/#/R-SPO-191402 Reduction of presqualene diphosphate to form squalene IEA Schizosaccharomyces pombe 15378 R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 15378 R-SPO-192033 https://reactome.org/PathwayBrowser/#/R-SPO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Schizosaccharomyces pombe 15378 R-SPO-192036 https://reactome.org/PathwayBrowser/#/R-SPO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Schizosaccharomyces pombe 15378 R-SPO-192067 https://reactome.org/PathwayBrowser/#/R-SPO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Schizosaccharomyces pombe 15378 R-SPO-192160 https://reactome.org/PathwayBrowser/#/R-SPO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Schizosaccharomyces pombe 15378 R-SPO-193746 https://reactome.org/PathwayBrowser/#/R-SPO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Schizosaccharomyces pombe 15378 R-SPO-193755 https://reactome.org/PathwayBrowser/#/R-SPO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Schizosaccharomyces pombe 15378 R-SPO-193758 https://reactome.org/PathwayBrowser/#/R-SPO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Schizosaccharomyces pombe 15378 R-SPO-193781 https://reactome.org/PathwayBrowser/#/R-SPO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Schizosaccharomyces pombe 15378 R-SPO-193800 https://reactome.org/PathwayBrowser/#/R-SPO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Schizosaccharomyces pombe 15378 R-SPO-193821 https://reactome.org/PathwayBrowser/#/R-SPO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Schizosaccharomyces pombe 15378 R-SPO-193824 https://reactome.org/PathwayBrowser/#/R-SPO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Schizosaccharomyces pombe 15378 R-SPO-193841 https://reactome.org/PathwayBrowser/#/R-SPO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Schizosaccharomyces pombe 15378 R-SPO-194023 https://reactome.org/PathwayBrowser/#/R-SPO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Schizosaccharomyces pombe 15378 R-SPO-194641 https://reactome.org/PathwayBrowser/#/R-SPO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 15378 R-SPO-194642 https://reactome.org/PathwayBrowser/#/R-SPO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Schizosaccharomyces pombe 15378 R-SPO-194669 https://reactome.org/PathwayBrowser/#/R-SPO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 15378 R-SPO-194674 https://reactome.org/PathwayBrowser/#/R-SPO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Schizosaccharomyces pombe 15378 R-SPO-194678 https://reactome.org/PathwayBrowser/#/R-SPO-194678 CYP51A1 demethylates LNSOL IEA Schizosaccharomyces pombe 15378 R-SPO-194698 https://reactome.org/PathwayBrowser/#/R-SPO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Schizosaccharomyces pombe 15378 R-SPO-194718 https://reactome.org/PathwayBrowser/#/R-SPO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Schizosaccharomyces pombe 15378 R-SPO-195664 https://reactome.org/PathwayBrowser/#/R-SPO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Schizosaccharomyces pombe 15378 R-SPO-196060 https://reactome.org/PathwayBrowser/#/R-SPO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Schizosaccharomyces pombe 15378 R-SPO-196753 https://reactome.org/PathwayBrowser/#/R-SPO-196753 2xPPCS ligates PPanK with Cys IEA Schizosaccharomyces pombe 15378 R-SPO-196754 https://reactome.org/PathwayBrowser/#/R-SPO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Schizosaccharomyces pombe 15378 R-SPO-196773 https://reactome.org/PathwayBrowser/#/R-SPO-196773 COASY phosphorylates DP-CoA IEA Schizosaccharomyces pombe 15378 R-SPO-196929 https://reactome.org/PathwayBrowser/#/R-SPO-196929 FLAD1 phosphorylates FMN IEA Schizosaccharomyces pombe 15378 R-SPO-196955 https://reactome.org/PathwayBrowser/#/R-SPO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Schizosaccharomyces pombe 15378 R-SPO-196964 https://reactome.org/PathwayBrowser/#/R-SPO-196964 RFK:Mg2+ phosphorylates RIB IEA Schizosaccharomyces pombe 15378 R-SPO-197186 https://reactome.org/PathwayBrowser/#/R-SPO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Schizosaccharomyces pombe 15378 R-SPO-197963 https://reactome.org/PathwayBrowser/#/R-SPO-197963 DHFR2 reduces FOLA to DHF IEA Schizosaccharomyces pombe 15378 R-SPO-197972 https://reactome.org/PathwayBrowser/#/R-SPO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Schizosaccharomyces pombe 15378 R-SPO-198824 https://reactome.org/PathwayBrowser/#/R-SPO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Schizosaccharomyces pombe 15378 R-SPO-200644 https://reactome.org/PathwayBrowser/#/R-SPO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Schizosaccharomyces pombe 15378 R-SPO-200676 https://reactome.org/PathwayBrowser/#/R-SPO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Schizosaccharomyces pombe 15378 R-SPO-200718 https://reactome.org/PathwayBrowser/#/R-SPO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Schizosaccharomyces pombe 15378 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 15378 R-SPO-204617 https://reactome.org/PathwayBrowser/#/R-SPO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Schizosaccharomyces pombe 15378 R-SPO-204647 https://reactome.org/PathwayBrowser/#/R-SPO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Schizosaccharomyces pombe 15378 R-SPO-204662 https://reactome.org/PathwayBrowser/#/R-SPO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Schizosaccharomyces pombe 15378 R-SPO-2161549 https://reactome.org/PathwayBrowser/#/R-SPO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Schizosaccharomyces pombe 15378 R-SPO-2161614 https://reactome.org/PathwayBrowser/#/R-SPO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Schizosaccharomyces pombe 15378 R-SPO-2162078 https://reactome.org/PathwayBrowser/#/R-SPO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Schizosaccharomyces pombe 15378 R-SPO-2162186 https://reactome.org/PathwayBrowser/#/R-SPO-2162186 COQ3 methylates DeMQ10H2 IEA Schizosaccharomyces pombe 15378 R-SPO-2162188 https://reactome.org/PathwayBrowser/#/R-SPO-2162188 COQ5 methylates MDMQ10H2 IEA Schizosaccharomyces pombe 15378 R-SPO-2162193 https://reactome.org/PathwayBrowser/#/R-SPO-2162193 COQ3 methylates DHDB IEA Schizosaccharomyces pombe 15378 R-SPO-2162194 https://reactome.org/PathwayBrowser/#/R-SPO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Schizosaccharomyces pombe 15378 R-SPO-2395517 https://reactome.org/PathwayBrowser/#/R-SPO-2395517 NADPH transfers electrons to FDXR IEA Schizosaccharomyces pombe 15378 R-SPO-2509827 https://reactome.org/PathwayBrowser/#/R-SPO-2509827 ITPA hydrolyses ITP to IMP IEA Schizosaccharomyces pombe 15378 R-SPO-2509831 https://reactome.org/PathwayBrowser/#/R-SPO-2509831 ITPA hydrolyses XTP to XMP IEA Schizosaccharomyces pombe 15378 R-SPO-2509838 https://reactome.org/PathwayBrowser/#/R-SPO-2509838 ITPA hydrolyses dITP to dIMP IEA Schizosaccharomyces pombe 15378 R-SPO-2730692 https://reactome.org/PathwayBrowser/#/R-SPO-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Schizosaccharomyces pombe 15378 R-SPO-3299680 https://reactome.org/PathwayBrowser/#/R-SPO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Schizosaccharomyces pombe 15378 R-SPO-3299682 https://reactome.org/PathwayBrowser/#/R-SPO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Schizosaccharomyces pombe 15378 R-SPO-3299691 https://reactome.org/PathwayBrowser/#/R-SPO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Schizosaccharomyces pombe 15378 R-SPO-3323079 https://reactome.org/PathwayBrowser/#/R-SPO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 15378 R-SPO-3777112 https://reactome.org/PathwayBrowser/#/R-SPO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Schizosaccharomyces pombe 15378 R-SPO-380608 https://reactome.org/PathwayBrowser/#/R-SPO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Schizosaccharomyces pombe 15378 R-SPO-389540 https://reactome.org/PathwayBrowser/#/R-SPO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 15378 R-SPO-389550 https://reactome.org/PathwayBrowser/#/R-SPO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 15378 R-SPO-425965 https://reactome.org/PathwayBrowser/#/R-SPO-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Schizosaccharomyces pombe 15378 R-SPO-425983 https://reactome.org/PathwayBrowser/#/R-SPO-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Schizosaccharomyces pombe 15378 R-SPO-425994 https://reactome.org/PathwayBrowser/#/R-SPO-425994 Na+/H+ exchanger transport (at cell membrane) IEA Schizosaccharomyces pombe 15378 R-SPO-426015 https://reactome.org/PathwayBrowser/#/R-SPO-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Schizosaccharomyces pombe 15378 R-SPO-426043 https://reactome.org/PathwayBrowser/#/R-SPO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Schizosaccharomyces pombe 15378 R-SPO-427555 https://reactome.org/PathwayBrowser/#/R-SPO-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Schizosaccharomyces pombe 15378 R-SPO-428007 https://reactome.org/PathwayBrowser/#/R-SPO-428007 Proton-coupled histidine and di-peptide cotransport IEA Schizosaccharomyces pombe 15378 R-SPO-428123 https://reactome.org/PathwayBrowser/#/R-SPO-428123 KDSR reduces 3-ketosphingoid IEA Schizosaccharomyces pombe 15378 R-SPO-428185 https://reactome.org/PathwayBrowser/#/R-SPO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Schizosaccharomyces pombe 15378 R-SPO-428259 https://reactome.org/PathwayBrowser/#/R-SPO-428259 DEGS1 dehydrogenates dihydroceramide IEA Schizosaccharomyces pombe 15378 R-SPO-428260 https://reactome.org/PathwayBrowser/#/R-SPO-428260 DEGS2 oxygenates dihydroceramide IEA Schizosaccharomyces pombe 15378 R-SPO-428273 https://reactome.org/PathwayBrowser/#/R-SPO-428273 SPHK1 phosphorylates sphingoid IEA Schizosaccharomyces pombe 15378 R-SPO-429101 https://reactome.org/PathwayBrowser/#/R-SPO-429101 HMIT co-transports myo-inositol with a proton IEA Schizosaccharomyces pombe 15378 R-SPO-434650 https://reactome.org/PathwayBrowser/#/R-SPO-434650 MATEs mediate extrusion of xenobiotics IEA Schizosaccharomyces pombe 15378 R-SPO-469659 https://reactome.org/PathwayBrowser/#/R-SPO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 15378 R-SPO-504054 https://reactome.org/PathwayBrowser/#/R-SPO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Schizosaccharomyces pombe 15378 R-SPO-508040 https://reactome.org/PathwayBrowser/#/R-SPO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Schizosaccharomyces pombe 15378 R-SPO-5362518 https://reactome.org/PathwayBrowser/#/R-SPO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Schizosaccharomyces pombe 15378 R-SPO-5362522 https://reactome.org/PathwayBrowser/#/R-SPO-5362522 ALDHs oxidise atRAL to atRA IEA Schizosaccharomyces pombe 15378 R-SPO-5362564 https://reactome.org/PathwayBrowser/#/R-SPO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Schizosaccharomyces pombe 15378 R-SPO-5362721 https://reactome.org/PathwayBrowser/#/R-SPO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Schizosaccharomyces pombe 15378 R-SPO-5419165 https://reactome.org/PathwayBrowser/#/R-SPO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Schizosaccharomyces pombe 15378 R-SPO-548831 https://reactome.org/PathwayBrowser/#/R-SPO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Schizosaccharomyces pombe 15378 R-SPO-5615668 https://reactome.org/PathwayBrowser/#/R-SPO-5615668 AKR1C3 reduces atRAL to atROL IEA Schizosaccharomyces pombe 15378 R-SPO-5652172 https://reactome.org/PathwayBrowser/#/R-SPO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Schizosaccharomyces pombe 15378 R-SPO-5652195 https://reactome.org/PathwayBrowser/#/R-SPO-5652195 SORD oxidizes D-sorbitol to Fru IEA Schizosaccharomyces pombe 15378 R-SPO-5661256 https://reactome.org/PathwayBrowser/#/R-SPO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Schizosaccharomyces pombe 15378 R-SPO-5662471 https://reactome.org/PathwayBrowser/#/R-SPO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Schizosaccharomyces pombe 15378 R-SPO-5690565 https://reactome.org/PathwayBrowser/#/R-SPO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15378 R-SPO-5692237 https://reactome.org/PathwayBrowser/#/R-SPO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Schizosaccharomyces pombe 15378 R-SPO-5693347 https://reactome.org/PathwayBrowser/#/R-SPO-5693347 CRYM reduces P2C to PPCA IEA Schizosaccharomyces pombe 15378 R-SPO-5693761 https://reactome.org/PathwayBrowser/#/R-SPO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Schizosaccharomyces pombe 15378 R-SPO-5694018 https://reactome.org/PathwayBrowser/#/R-SPO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Schizosaccharomyces pombe 15378 R-SPO-5696091 https://reactome.org/PathwayBrowser/#/R-SPO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Schizosaccharomyces pombe 15378 R-SPO-5696822 https://reactome.org/PathwayBrowser/#/R-SPO-5696822 AKR1B15 reduces EST17b to E1 IEA Schizosaccharomyces pombe 15378 R-SPO-6783221 https://reactome.org/PathwayBrowser/#/R-SPO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Schizosaccharomyces pombe 15378 R-SPO-6783939 https://reactome.org/PathwayBrowser/#/R-SPO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 15378 R-SPO-6783955 https://reactome.org/PathwayBrowser/#/R-SPO-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 15378 R-SPO-6793590 https://reactome.org/PathwayBrowser/#/R-SPO-6793590 LIPT2 transfers octanoyl group to GCSH IEA Schizosaccharomyces pombe 15378 R-SPO-6801342 https://reactome.org/PathwayBrowser/#/R-SPO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Schizosaccharomyces pombe 15378 R-SPO-6806967 https://reactome.org/PathwayBrowser/#/R-SPO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Schizosaccharomyces pombe 15378 R-SPO-6807053 https://reactome.org/PathwayBrowser/#/R-SPO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Schizosaccharomyces pombe 15378 R-SPO-6809287 https://reactome.org/PathwayBrowser/#/R-SPO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Schizosaccharomyces pombe 15378 R-SPO-6813749 https://reactome.org/PathwayBrowser/#/R-SPO-6813749 ALDH1A1 oxidises GA to DGA IEA Schizosaccharomyces pombe 15378 R-SPO-70377 https://reactome.org/PathwayBrowser/#/R-SPO-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Schizosaccharomyces pombe 15378 R-SPO-70420 https://reactome.org/PathwayBrowser/#/R-SPO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Schizosaccharomyces pombe 15378 R-SPO-70449 https://reactome.org/PathwayBrowser/#/R-SPO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Schizosaccharomyces pombe 15378 R-SPO-70467 https://reactome.org/PathwayBrowser/#/R-SPO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 15378 R-SPO-70482 https://reactome.org/PathwayBrowser/#/R-SPO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Schizosaccharomyces pombe 15378 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 15378 R-SPO-70664 https://reactome.org/PathwayBrowser/#/R-SPO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 15378 R-SPO-70670 https://reactome.org/PathwayBrowser/#/R-SPO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Schizosaccharomyces pombe 15378 R-SPO-70938 https://reactome.org/PathwayBrowser/#/R-SPO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Schizosaccharomyces pombe 15378 R-SPO-70940 https://reactome.org/PathwayBrowser/#/R-SPO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Schizosaccharomyces pombe 15378 R-SPO-70975 https://reactome.org/PathwayBrowser/#/R-SPO-70975 CS acetylates OA to citrate IEA Schizosaccharomyces pombe 15378 R-SPO-70979 https://reactome.org/PathwayBrowser/#/R-SPO-70979 MDH2 dimer dehydrogenates MAL IEA Schizosaccharomyces pombe 15378 R-SPO-71286 https://reactome.org/PathwayBrowser/#/R-SPO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Schizosaccharomyces pombe 15378 R-SPO-71299 https://reactome.org/PathwayBrowser/#/R-SPO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 15378 R-SPO-71401 https://reactome.org/PathwayBrowser/#/R-SPO-71401 OGDH dimer decarboxylates 2-OG IEA Schizosaccharomyces pombe 15378 R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 15378 R-SPO-71682 https://reactome.org/PathwayBrowser/#/R-SPO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 15378 R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 15378 R-SPO-71707 https://reactome.org/PathwayBrowser/#/R-SPO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Schizosaccharomyces pombe 15378 R-SPO-71723 https://reactome.org/PathwayBrowser/#/R-SPO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Schizosaccharomyces pombe 15378 R-SPO-73571 https://reactome.org/PathwayBrowser/#/R-SPO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Schizosaccharomyces pombe 15378 R-SPO-73573 https://reactome.org/PathwayBrowser/#/R-SPO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Schizosaccharomyces pombe 15378 R-SPO-73577 https://reactome.org/PathwayBrowser/#/R-SPO-73577 CAD hexamer transforms L-Gln to CAP IEA Schizosaccharomyces pombe 15378 R-SPO-73591 https://reactome.org/PathwayBrowser/#/R-SPO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Schizosaccharomyces pombe 15378 R-SPO-73620 https://reactome.org/PathwayBrowser/#/R-SPO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Schizosaccharomyces pombe 15378 R-SPO-73647 https://reactome.org/PathwayBrowser/#/R-SPO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Schizosaccharomyces pombe 15378 R-SPO-73666 https://reactome.org/PathwayBrowser/#/R-SPO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Schizosaccharomyces pombe 15378 R-SPO-73792 https://reactome.org/PathwayBrowser/#/R-SPO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Schizosaccharomyces pombe 15378 R-SPO-73794 https://reactome.org/PathwayBrowser/#/R-SPO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Schizosaccharomyces pombe 15378 R-SPO-73810 https://reactome.org/PathwayBrowser/#/R-SPO-73810 FGAM + ATP => AIR + ADP + Pi IEA Schizosaccharomyces pombe 15378 R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 15378 R-SPO-73813 https://reactome.org/PathwayBrowser/#/R-SPO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Schizosaccharomyces pombe 15378 R-SPO-73814 https://reactome.org/PathwayBrowser/#/R-SPO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Schizosaccharomyces pombe 15378 R-SPO-73912 https://reactome.org/PathwayBrowser/#/R-SPO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Schizosaccharomyces pombe 15378 R-SPO-73920 https://reactome.org/PathwayBrowser/#/R-SPO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Schizosaccharomyces pombe 15378 R-SPO-74255 https://reactome.org/PathwayBrowser/#/R-SPO-74255 Guanine + H2O => Xanthine + NH4+ IEA Schizosaccharomyces pombe 15378 R-SPO-74723 https://reactome.org/PathwayBrowser/#/R-SPO-74723 Endosome acidification IEA Schizosaccharomyces pombe 15378 R-SPO-75889 https://reactome.org/PathwayBrowser/#/R-SPO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Schizosaccharomyces pombe 15378 R-SPO-804969 https://reactome.org/PathwayBrowser/#/R-SPO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Schizosaccharomyces pombe 15378 R-SPO-8847579 https://reactome.org/PathwayBrowser/#/R-SPO-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15378 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15378 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 15378 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15378 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15378 R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 15378 R-SPO-8862137 https://reactome.org/PathwayBrowser/#/R-SPO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Schizosaccharomyces pombe 15378 R-SPO-8862152 https://reactome.org/PathwayBrowser/#/R-SPO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Schizosaccharomyces pombe 15378 R-SPO-888548 https://reactome.org/PathwayBrowser/#/R-SPO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Schizosaccharomyces pombe 15378 R-SPO-8952873 https://reactome.org/PathwayBrowser/#/R-SPO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Schizosaccharomyces pombe 15378 R-SPO-8955760 https://reactome.org/PathwayBrowser/#/R-SPO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Schizosaccharomyces pombe 15378 R-SPO-9012016 https://reactome.org/PathwayBrowser/#/R-SPO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Schizosaccharomyces pombe 15378 R-SPO-917841 https://reactome.org/PathwayBrowser/#/R-SPO-917841 Acidification of Tf:TfR1 containing endosome IEA Schizosaccharomyces pombe 15378 R-SPO-9620103 https://reactome.org/PathwayBrowser/#/R-SPO-9620103 ALDH2 transforms GTN to NO IEA Schizosaccharomyces pombe 15378 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 15378 R-SPO-9705713 https://reactome.org/PathwayBrowser/#/R-SPO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 15378 R-SPO-9705714 https://reactome.org/PathwayBrowser/#/R-SPO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 15378 R-SPO-9709098 https://reactome.org/PathwayBrowser/#/R-SPO-9709098 DHFR dimer reduces FOLA to DHF IEA Schizosaccharomyces pombe 15378 R-SPO-9748945 https://reactome.org/PathwayBrowser/#/R-SPO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Schizosaccharomyces pombe 15378 R-SPO-9748957 https://reactome.org/PathwayBrowser/#/R-SPO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Schizosaccharomyces pombe 15378 R-SPO-9758682 https://reactome.org/PathwayBrowser/#/R-SPO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Schizosaccharomyces pombe 15378 R-SPO-9759259 https://reactome.org/PathwayBrowser/#/R-SPO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Schizosaccharomyces pombe 15378 R-SPO-9760094 https://reactome.org/PathwayBrowser/#/R-SPO-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Schizosaccharomyces pombe 15378 R-SPO-9837337 https://reactome.org/PathwayBrowser/#/R-SPO-9837337 DCAKD phosphorylates DP-CoA IEA Schizosaccharomyces pombe 15378 R-SPO-9843721 https://reactome.org/PathwayBrowser/#/R-SPO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Schizosaccharomyces pombe 15378 R-SPO-9853499 https://reactome.org/PathwayBrowser/#/R-SPO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 15378 R-SPO-9861616 https://reactome.org/PathwayBrowser/#/R-SPO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 15378 R-SPO-9861734 https://reactome.org/PathwayBrowser/#/R-SPO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Schizosaccharomyces pombe 15378 R-SSC-109343 https://reactome.org/PathwayBrowser/#/R-SSC-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Sus scrofa 15378 R-SSC-111524 https://reactome.org/PathwayBrowser/#/R-SSC-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Sus scrofa 15378 R-SSC-1222376 https://reactome.org/PathwayBrowser/#/R-SSC-1222376 NOX2 generates superoxide from oxygen IEA Sus scrofa 15378 R-SSC-1222516 https://reactome.org/PathwayBrowser/#/R-SSC-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Sus scrofa 15378 R-SSC-1236967 https://reactome.org/PathwayBrowser/#/R-SSC-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Sus scrofa 15378 R-SSC-1237045 https://reactome.org/PathwayBrowser/#/R-SSC-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Sus scrofa 15378 R-SSC-1237047 https://reactome.org/PathwayBrowser/#/R-SSC-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Sus scrofa 15378 R-SSC-1237059 https://reactome.org/PathwayBrowser/#/R-SSC-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Sus scrofa 15378 R-SSC-1237081 https://reactome.org/PathwayBrowser/#/R-SSC-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Sus scrofa 15378 R-SSC-1237129 https://reactome.org/PathwayBrowser/#/R-SSC-1237129 Acireductone is created IEA Sus scrofa 15378 R-SSC-1237325 https://reactome.org/PathwayBrowser/#/R-SSC-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Sus scrofa 15378 R-SSC-1247668 https://reactome.org/PathwayBrowser/#/R-SSC-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Sus scrofa 15378 R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 15378 R-SSC-140359 https://reactome.org/PathwayBrowser/#/R-SSC-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Sus scrofa 15378 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 15378 R-SSC-1475017 https://reactome.org/PathwayBrowser/#/R-SSC-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Sus scrofa 15378 R-SSC-1475022 https://reactome.org/PathwayBrowser/#/R-SSC-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Sus scrofa 15378 R-SSC-1475025 https://reactome.org/PathwayBrowser/#/R-SSC-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Sus scrofa 15378 R-SSC-1475026 https://reactome.org/PathwayBrowser/#/R-SSC-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Sus scrofa 15378 R-SSC-1475028 https://reactome.org/PathwayBrowser/#/R-SSC-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Sus scrofa 15378 R-SSC-1475032 https://reactome.org/PathwayBrowser/#/R-SSC-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Sus scrofa 15378 R-SSC-1475435 https://reactome.org/PathwayBrowser/#/R-SSC-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Sus scrofa 15378 R-SSC-1475436 https://reactome.org/PathwayBrowser/#/R-SSC-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Sus scrofa 15378 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 15378 R-SSC-1497869 https://reactome.org/PathwayBrowser/#/R-SSC-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Sus scrofa 15378 R-SSC-1562626 https://reactome.org/PathwayBrowser/#/R-SSC-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Sus scrofa 15378 R-SSC-156526 https://reactome.org/PathwayBrowser/#/R-SSC-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Sus scrofa 15378 R-SSC-158609 https://reactome.org/PathwayBrowser/#/R-SSC-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Sus scrofa 15378 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 15378 R-SSC-1605797 https://reactome.org/PathwayBrowser/#/R-SSC-1605797 SMPD1 hydrolyzes SPHM IEA Sus scrofa 15378 R-SSC-1606273 https://reactome.org/PathwayBrowser/#/R-SSC-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Sus scrofa 15378 R-SSC-1606288 https://reactome.org/PathwayBrowser/#/R-SSC-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Sus scrofa 15378 R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 15378 R-SSC-1614362 https://reactome.org/PathwayBrowser/#/R-SSC-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Sus scrofa 15378 R-SSC-1614605 https://reactome.org/PathwayBrowser/#/R-SSC-1614605 Persulfide sulfur is dioxygenated IEA Sus scrofa 15378 R-SSC-162730 https://reactome.org/PathwayBrowser/#/R-SSC-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Sus scrofa 15378 R-SSC-163120 https://reactome.org/PathwayBrowser/#/R-SSC-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Sus scrofa 15378 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa 15378 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Sus scrofa 15378 R-SSC-1638104 https://reactome.org/PathwayBrowser/#/R-SSC-1638104 UGCG transfers glucose to ceramide IEA Sus scrofa 15378 R-SSC-1638845 https://reactome.org/PathwayBrowser/#/R-SSC-1638845 CERK phosphorylates CERA to form C1P IEA Sus scrofa 15378 R-SSC-1640164 https://reactome.org/PathwayBrowser/#/R-SSC-1640164 ENPP7 hydrolyzes sphingomyelin IEA Sus scrofa 15378 R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa 15378 R-SSC-164834 https://reactome.org/PathwayBrowser/#/R-SSC-164834 Enzyme-bound ATP is released IEA Sus scrofa 15378 R-SSC-1655453 https://reactome.org/PathwayBrowser/#/R-SSC-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Sus scrofa 15378 R-SSC-1655879 https://reactome.org/PathwayBrowser/#/R-SSC-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Sus scrofa 15378 R-SSC-1678920 https://reactome.org/PathwayBrowser/#/R-SSC-1678920 TLR processing at low pH IEA Sus scrofa 15378 R-SSC-170026 https://reactome.org/PathwayBrowser/#/R-SSC-170026 Protons are translocated from the intermembrane space to the matrix IEA Sus scrofa 15378 R-SSC-173597 https://reactome.org/PathwayBrowser/#/R-SSC-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Sus scrofa 15378 R-SSC-174389 https://reactome.org/PathwayBrowser/#/R-SSC-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Sus scrofa 15378 R-SSC-174392 https://reactome.org/PathwayBrowser/#/R-SSC-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Sus scrofa 15378 R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa 15378 R-SSC-189421 https://reactome.org/PathwayBrowser/#/R-SSC-189421 CPO transforms COPRO3 to PPGEN9 IEA Sus scrofa 15378 R-SSC-189425 https://reactome.org/PathwayBrowser/#/R-SSC-189425 UROD decarboxylates URO3 to COPRO3 IEA Sus scrofa 15378 R-SSC-189439 https://reactome.org/PathwayBrowser/#/R-SSC-189439 ALAD condenses 2 dALAs to form PBG IEA Sus scrofa 15378 R-SSC-189442 https://reactome.org/PathwayBrowser/#/R-SSC-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Sus scrofa 15378 R-SSC-189465 https://reactome.org/PathwayBrowser/#/R-SSC-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Sus scrofa 15378 R-SSC-190182 https://reactome.org/PathwayBrowser/#/R-SSC-190182 UROD decarboxylates URO1 to COPRO1 IEA Sus scrofa 15378 R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 15378 R-SSC-191323 https://reactome.org/PathwayBrowser/#/R-SSC-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Sus scrofa 15378 R-SSC-191352 https://reactome.org/PathwayBrowser/#/R-SSC-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Sus scrofa 15378 R-SSC-191402 https://reactome.org/PathwayBrowser/#/R-SSC-191402 Reduction of presqualene diphosphate to form squalene IEA Sus scrofa 15378 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 15378 R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 15378 R-SSC-191999 https://reactome.org/PathwayBrowser/#/R-SSC-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Sus scrofa 15378 R-SSC-192033 https://reactome.org/PathwayBrowser/#/R-SSC-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Sus scrofa 15378 R-SSC-192036 https://reactome.org/PathwayBrowser/#/R-SSC-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Sus scrofa 15378 R-SSC-192042 https://reactome.org/PathwayBrowser/#/R-SSC-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 15378 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 15378 R-SSC-192054 https://reactome.org/PathwayBrowser/#/R-SSC-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Sus scrofa 15378 R-SSC-192061 https://reactome.org/PathwayBrowser/#/R-SSC-192061 CYP46A1 24-hydroxylates CHOL IEA Sus scrofa 15378 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 15378 R-SSC-192067 https://reactome.org/PathwayBrowser/#/R-SSC-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Sus scrofa 15378 R-SSC-192097 https://reactome.org/PathwayBrowser/#/R-SSC-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Sus scrofa 15378 R-SSC-192123 https://reactome.org/PathwayBrowser/#/R-SSC-192123 CYP27A1 27-hydroxylates CHOL IEA Sus scrofa 15378 R-SSC-192157 https://reactome.org/PathwayBrowser/#/R-SSC-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Sus scrofa 15378 R-SSC-192160 https://reactome.org/PathwayBrowser/#/R-SSC-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Sus scrofa 15378 R-SSC-192178 https://reactome.org/PathwayBrowser/#/R-SSC-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Sus scrofa 15378 R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 15378 R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 15378 R-SSC-193064 https://reactome.org/PathwayBrowser/#/R-SSC-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Sus scrofa 15378 R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 15378 R-SSC-193068 https://reactome.org/PathwayBrowser/#/R-SSC-193068 CYP17A1 17-hydroxylates PREG IEA Sus scrofa 15378 R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 15378 R-SSC-193072 https://reactome.org/PathwayBrowser/#/R-SSC-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Sus scrofa 15378 R-SSC-193073 https://reactome.org/PathwayBrowser/#/R-SSC-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Sus scrofa 15378 R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 15378 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 15378 R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 15378 R-SSC-193393 https://reactome.org/PathwayBrowser/#/R-SSC-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Sus scrofa 15378 R-SSC-193460 https://reactome.org/PathwayBrowser/#/R-SSC-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Sus scrofa 15378 R-SSC-193497 https://reactome.org/PathwayBrowser/#/R-SSC-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Sus scrofa 15378 R-SSC-193709 https://reactome.org/PathwayBrowser/#/R-SSC-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Sus scrofa 15378 R-SSC-193713 https://reactome.org/PathwayBrowser/#/R-SSC-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Sus scrofa 15378 R-SSC-193719 https://reactome.org/PathwayBrowser/#/R-SSC-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 15378 R-SSC-193737 https://reactome.org/PathwayBrowser/#/R-SSC-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Sus scrofa 15378 R-SSC-193746 https://reactome.org/PathwayBrowser/#/R-SSC-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Sus scrofa 15378 R-SSC-193755 https://reactome.org/PathwayBrowser/#/R-SSC-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Sus scrofa 15378 R-SSC-193758 https://reactome.org/PathwayBrowser/#/R-SSC-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Sus scrofa 15378 R-SSC-193780 https://reactome.org/PathwayBrowser/#/R-SSC-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Sus scrofa 15378 R-SSC-193781 https://reactome.org/PathwayBrowser/#/R-SSC-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Sus scrofa 15378 R-SSC-193787 https://reactome.org/PathwayBrowser/#/R-SSC-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Sus scrofa 15378 R-SSC-193789 https://reactome.org/PathwayBrowser/#/R-SSC-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Sus scrofa 15378 R-SSC-193792 https://reactome.org/PathwayBrowser/#/R-SSC-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Sus scrofa 15378 R-SSC-193800 https://reactome.org/PathwayBrowser/#/R-SSC-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Sus scrofa 15378 R-SSC-193816 https://reactome.org/PathwayBrowser/#/R-SSC-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Sus scrofa 15378 R-SSC-193821 https://reactome.org/PathwayBrowser/#/R-SSC-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Sus scrofa 15378 R-SSC-193824 https://reactome.org/PathwayBrowser/#/R-SSC-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Sus scrofa 15378 R-SSC-193841 https://reactome.org/PathwayBrowser/#/R-SSC-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Sus scrofa 15378 R-SSC-193845 https://reactome.org/PathwayBrowser/#/R-SSC-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Sus scrofa 15378 R-SSC-193964 https://reactome.org/PathwayBrowser/#/R-SSC-193964 CYP21A2 21-hydroxylates PROG IEA Sus scrofa 15378 R-SSC-193965 https://reactome.org/PathwayBrowser/#/R-SSC-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Sus scrofa 15378 R-SSC-193981 https://reactome.org/PathwayBrowser/#/R-SSC-193981 CYP21A2 oxidises 17HPROG IEA Sus scrofa 15378 R-SSC-193995 https://reactome.org/PathwayBrowser/#/R-SSC-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Sus scrofa 15378 R-SSC-193997 https://reactome.org/PathwayBrowser/#/R-SSC-193997 CYP11B1 oxidises 11DCORT IEA Sus scrofa 15378 R-SSC-194017 https://reactome.org/PathwayBrowser/#/R-SSC-194017 CYP11B2 oxidises 11DCORST to CORST IEA Sus scrofa 15378 R-SSC-194023 https://reactome.org/PathwayBrowser/#/R-SSC-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Sus scrofa 15378 R-SSC-194632 https://reactome.org/PathwayBrowser/#/R-SSC-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Sus scrofa 15378 R-SSC-194641 https://reactome.org/PathwayBrowser/#/R-SSC-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15378 R-SSC-194642 https://reactome.org/PathwayBrowser/#/R-SSC-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Sus scrofa 15378 R-SSC-194669 https://reactome.org/PathwayBrowser/#/R-SSC-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15378 R-SSC-194674 https://reactome.org/PathwayBrowser/#/R-SSC-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Sus scrofa 15378 R-SSC-194678 https://reactome.org/PathwayBrowser/#/R-SSC-194678 CYP51A1 demethylates LNSOL IEA Sus scrofa 15378 R-SSC-194689 https://reactome.org/PathwayBrowser/#/R-SSC-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15378 R-SSC-194698 https://reactome.org/PathwayBrowser/#/R-SSC-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Sus scrofa 15378 R-SSC-194718 https://reactome.org/PathwayBrowser/#/R-SSC-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Sus scrofa 15378 R-SSC-195664 https://reactome.org/PathwayBrowser/#/R-SSC-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Sus scrofa 15378 R-SSC-196060 https://reactome.org/PathwayBrowser/#/R-SSC-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Sus scrofa 15378 R-SSC-196350 https://reactome.org/PathwayBrowser/#/R-SSC-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Sus scrofa 15378 R-SSC-196372 https://reactome.org/PathwayBrowser/#/R-SSC-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Sus scrofa 15378 R-SSC-196402 https://reactome.org/PathwayBrowser/#/R-SSC-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Sus scrofa 15378 R-SSC-196417 https://reactome.org/PathwayBrowser/#/R-SSC-196417 Reduction of desmosterol to cholesterol IEA Sus scrofa 15378 R-SSC-196753 https://reactome.org/PathwayBrowser/#/R-SSC-196753 2xPPCS ligates PPanK with Cys IEA Sus scrofa 15378 R-SSC-196754 https://reactome.org/PathwayBrowser/#/R-SSC-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Sus scrofa 15378 R-SSC-196773 https://reactome.org/PathwayBrowser/#/R-SSC-196773 COASY phosphorylates DP-CoA IEA Sus scrofa 15378 R-SSC-196840 https://reactome.org/PathwayBrowser/#/R-SSC-196840 3xPPCDC:3FMN decarboxylates PPC IEA Sus scrofa 15378 R-SSC-196857 https://reactome.org/PathwayBrowser/#/R-SSC-196857 PANK2 phosphorylates PanK IEA Sus scrofa 15378 R-SSC-196929 https://reactome.org/PathwayBrowser/#/R-SSC-196929 FLAD1 phosphorylates FMN IEA Sus scrofa 15378 R-SSC-196955 https://reactome.org/PathwayBrowser/#/R-SSC-196955 2xENPP1 hydrolyzes FAD to FMN IEA Sus scrofa 15378 R-SSC-196964 https://reactome.org/PathwayBrowser/#/R-SSC-196964 RFK:Mg2+ phosphorylates RIB IEA Sus scrofa 15378 R-SSC-197186 https://reactome.org/PathwayBrowser/#/R-SSC-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Sus scrofa 15378 R-SSC-197268 https://reactome.org/PathwayBrowser/#/R-SSC-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Sus scrofa 15378 R-SSC-197963 https://reactome.org/PathwayBrowser/#/R-SSC-197963 DHFR2 reduces FOLA to DHF IEA Sus scrofa 15378 R-SSC-197972 https://reactome.org/PathwayBrowser/#/R-SSC-197972 DHF is reduced to tetrahydrofolate (THF) IEA Sus scrofa 15378 R-SSC-198824 https://reactome.org/PathwayBrowser/#/R-SSC-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Sus scrofa 15378 R-SSC-199203 https://reactome.org/PathwayBrowser/#/R-SSC-199203 PANK1/3 phosphorylate PanK IEA Sus scrofa 15378 R-SSC-200644 https://reactome.org/PathwayBrowser/#/R-SSC-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Sus scrofa 15378 R-SSC-200676 https://reactome.org/PathwayBrowser/#/R-SSC-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Sus scrofa 15378 R-SSC-200718 https://reactome.org/PathwayBrowser/#/R-SSC-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Sus scrofa 15378 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 15378 R-SSC-204617 https://reactome.org/PathwayBrowser/#/R-SSC-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Sus scrofa 15378 R-SSC-204647 https://reactome.org/PathwayBrowser/#/R-SSC-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Sus scrofa 15378 R-SSC-204662 https://reactome.org/PathwayBrowser/#/R-SSC-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Sus scrofa 15378 R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 15378 R-SSC-209772 https://reactome.org/PathwayBrowser/#/R-SSC-209772 Thyroxine is deiodinated to triiodothyronine IEA Sus scrofa 15378 R-SSC-209821 https://reactome.org/PathwayBrowser/#/R-SSC-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Sus scrofa 15378 R-SSC-209845 https://reactome.org/PathwayBrowser/#/R-SSC-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Sus scrofa 15378 R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 15378 R-SSC-209903 https://reactome.org/PathwayBrowser/#/R-SSC-209903 Noradrenaline is converted to adrenaline IEA Sus scrofa 15378 R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 15378 R-SSC-210404 https://reactome.org/PathwayBrowser/#/R-SSC-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Sus scrofa 15378 R-SSC-211873 https://reactome.org/PathwayBrowser/#/R-SSC-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Sus scrofa 15378 R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 15378 R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa 15378 R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 15378 R-SSC-211904 https://reactome.org/PathwayBrowser/#/R-SSC-211904 CYP4F12 18-hydroxylates ARA IEA Sus scrofa 15378 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 15378 R-SSC-211919 https://reactome.org/PathwayBrowser/#/R-SSC-211919 CYP4F8 19-hydroxylates PGH2 IEA Sus scrofa 15378 R-SSC-211923 https://reactome.org/PathwayBrowser/#/R-SSC-211923 CYP26C1 4-hydroxylates 9cRA IEA Sus scrofa 15378 R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa 15378 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 15378 R-SSC-211948 https://reactome.org/PathwayBrowser/#/R-SSC-211948 CYP3A4 can N-demethylate loperamide IEA Sus scrofa 15378 R-SSC-211950 https://reactome.org/PathwayBrowser/#/R-SSC-211950 CYP24A1 24-hydroxylates CTL IEA Sus scrofa 15378 R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 15378 R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 15378 R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa 15378 R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa 15378 R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa 15378 R-SSC-211968 https://reactome.org/PathwayBrowser/#/R-SSC-211968 CYP2W1 oxidises INDOL IEA Sus scrofa 15378 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 15378 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 15378 R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa 15378 R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 15378 R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa 15378 R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 15378 R-SSC-213175 https://reactome.org/PathwayBrowser/#/R-SSC-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Sus scrofa 15378 R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa 15378 R-SSC-2161187 https://reactome.org/PathwayBrowser/#/R-SSC-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Sus scrofa 15378 R-SSC-2161549 https://reactome.org/PathwayBrowser/#/R-SSC-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Sus scrofa 15378 R-SSC-2161614 https://reactome.org/PathwayBrowser/#/R-SSC-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Sus scrofa 15378 R-SSC-2161617 https://reactome.org/PathwayBrowser/#/R-SSC-2161617 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 TAS Sus scrofa 15378 R-SSC-2161651 https://reactome.org/PathwayBrowser/#/R-SSC-2161651 PGE2 is converted to PGF2a by CBR1 IEA Sus scrofa 15378 R-SSC-2161745 https://reactome.org/PathwayBrowser/#/R-SSC-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Sus scrofa 15378 R-SSC-2161779 https://reactome.org/PathwayBrowser/#/R-SSC-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Sus scrofa 15378 R-SSC-2161792 https://reactome.org/PathwayBrowser/#/R-SSC-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Sus scrofa 15378 R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Sus scrofa 15378 R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa 15378 R-SSC-2161847 https://reactome.org/PathwayBrowser/#/R-SSC-2161847 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 TAS Sus scrofa 15378 R-SSC-2161890 https://reactome.org/PathwayBrowser/#/R-SSC-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Sus scrofa 15378 R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Sus scrofa 15378 R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa 15378 R-SSC-2161951 https://reactome.org/PathwayBrowser/#/R-SSC-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Sus scrofa 15378 R-SSC-2162078 https://reactome.org/PathwayBrowser/#/R-SSC-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Sus scrofa 15378 R-SSC-2162186 https://reactome.org/PathwayBrowser/#/R-SSC-2162186 COQ3 methylates DeMQ10H2 IEA Sus scrofa 15378 R-SSC-2162188 https://reactome.org/PathwayBrowser/#/R-SSC-2162188 COQ5 methylates MDMQ10H2 IEA Sus scrofa 15378 R-SSC-2162193 https://reactome.org/PathwayBrowser/#/R-SSC-2162193 COQ3 methylates DHDB IEA Sus scrofa 15378 R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa 15378 R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 15378 R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 15378 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 15378 R-SSC-2395512 https://reactome.org/PathwayBrowser/#/R-SSC-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Sus scrofa 15378 R-SSC-2395517 https://reactome.org/PathwayBrowser/#/R-SSC-2395517 NADPH transfers electrons to FDXR IEA Sus scrofa 15378 R-SSC-2395818 https://reactome.org/PathwayBrowser/#/R-SSC-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Sus scrofa 15378 R-SSC-2395849 https://reactome.org/PathwayBrowser/#/R-SSC-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 15378 R-SSC-2395869 https://reactome.org/PathwayBrowser/#/R-SSC-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 15378 R-SSC-2395872 https://reactome.org/PathwayBrowser/#/R-SSC-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Sus scrofa 15378 R-SSC-2395873 https://reactome.org/PathwayBrowser/#/R-SSC-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Sus scrofa 15378 R-SSC-2395876 https://reactome.org/PathwayBrowser/#/R-SSC-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 15378 R-SSC-2395879 https://reactome.org/PathwayBrowser/#/R-SSC-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 15378 R-SSC-2395965 https://reactome.org/PathwayBrowser/#/R-SSC-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Sus scrofa 15378 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 15378 R-SSC-2454081 https://reactome.org/PathwayBrowser/#/R-SSC-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Sus scrofa 15378 R-SSC-2464822 https://reactome.org/PathwayBrowser/#/R-SSC-2464822 RDH12 reduces atRAL to atROL IEA Sus scrofa 15378 R-SSC-2465940 https://reactome.org/PathwayBrowser/#/R-SSC-2465940 atRAL is reduced to atROL IEA Sus scrofa 15378 R-SSC-2509793 https://reactome.org/PathwayBrowser/#/R-SSC-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Sus scrofa 15378 R-SSC-2509816 https://reactome.org/PathwayBrowser/#/R-SSC-2509816 NUDT16 hydrolyses IDP to IMP IEA Sus scrofa 15378 R-SSC-2509827 https://reactome.org/PathwayBrowser/#/R-SSC-2509827 ITPA hydrolyses ITP to IMP IEA Sus scrofa 15378 R-SSC-2509831 https://reactome.org/PathwayBrowser/#/R-SSC-2509831 ITPA hydrolyses XTP to XMP IEA Sus scrofa 15378 R-SSC-2509838 https://reactome.org/PathwayBrowser/#/R-SSC-2509838 ITPA hydrolyses dITP to dIMP IEA Sus scrofa 15378 R-SSC-2534378 https://reactome.org/PathwayBrowser/#/R-SSC-2534378 Hv1 Mediated H+ Permeability IEA Sus scrofa 15378 R-SSC-264615 https://reactome.org/PathwayBrowser/#/R-SSC-264615 Loading of acetylcholine in synaptic vesicles IEA Sus scrofa 15378 R-SSC-2671885 https://reactome.org/PathwayBrowser/#/R-SSC-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Sus scrofa 15378 R-SSC-2730692 https://reactome.org/PathwayBrowser/#/R-SSC-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Sus scrofa 15378 R-SSC-2730959 https://reactome.org/PathwayBrowser/#/R-SSC-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Sus scrofa 15378 R-SSC-2855252 https://reactome.org/PathwayBrowser/#/R-SSC-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Sus scrofa 15378 R-SSC-2872444 https://reactome.org/PathwayBrowser/#/R-SSC-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Sus scrofa 15378 R-SSC-2889070 https://reactome.org/PathwayBrowser/#/R-SSC-2889070 SLC9B2 exchanges Na+ for H+ IEA Sus scrofa 15378 R-SSC-3095889 https://reactome.org/PathwayBrowser/#/R-SSC-3095889 MMACHC dealkylates RCbl IEA Sus scrofa 15378 R-SSC-3149518 https://reactome.org/PathwayBrowser/#/R-SSC-3149518 MTRR reduces cob(II)alamin to meCbl IEA Sus scrofa 15378 R-SSC-3149519 https://reactome.org/PathwayBrowser/#/R-SSC-3149519 MMACHC decyanates CNCbl IEA Sus scrofa 15378 R-SSC-3159253 https://reactome.org/PathwayBrowser/#/R-SSC-3159253 MMAB adenosylates cob(I)alamin IEA Sus scrofa 15378 R-SSC-3299680 https://reactome.org/PathwayBrowser/#/R-SSC-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Sus scrofa 15378 R-SSC-3299682 https://reactome.org/PathwayBrowser/#/R-SSC-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Sus scrofa 15378 R-SSC-3299691 https://reactome.org/PathwayBrowser/#/R-SSC-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Sus scrofa 15378 R-SSC-3323079 https://reactome.org/PathwayBrowser/#/R-SSC-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 15378 R-SSC-350869 https://reactome.org/PathwayBrowser/#/R-SSC-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Sus scrofa 15378 R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa 15378 R-SSC-352174 https://reactome.org/PathwayBrowser/#/R-SSC-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Sus scrofa 15378 R-SSC-352182 https://reactome.org/PathwayBrowser/#/R-SSC-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Sus scrofa 15378 R-SSC-372448 https://reactome.org/PathwayBrowser/#/R-SSC-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Sus scrofa 15378 R-SSC-373867 https://reactome.org/PathwayBrowser/#/R-SSC-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-SSC-373875 https://reactome.org/PathwayBrowser/#/R-SSC-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Sus scrofa 15378 R-SSC-375405 https://reactome.org/PathwayBrowser/#/R-SSC-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-SSC-375417 https://reactome.org/PathwayBrowser/#/R-SSC-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Sus scrofa 15378 R-SSC-3777112 https://reactome.org/PathwayBrowser/#/R-SSC-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Sus scrofa 15378 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15378 R-SSC-380608 https://reactome.org/PathwayBrowser/#/R-SSC-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Sus scrofa 15378 R-SSC-389540 https://reactome.org/PathwayBrowser/#/R-SSC-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 15378 R-SSC-389550 https://reactome.org/PathwayBrowser/#/R-SSC-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 15378 R-SSC-389609 https://reactome.org/PathwayBrowser/#/R-SSC-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Sus scrofa 15378 R-SSC-389826 https://reactome.org/PathwayBrowser/#/R-SSC-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Sus scrofa 15378 R-SSC-390425 https://reactome.org/PathwayBrowser/#/R-SSC-390425 FAR1 reduces PalmCoA to HXOL IEA Sus scrofa 15378 R-SSC-390438 https://reactome.org/PathwayBrowser/#/R-SSC-390438 FAR2 reduces PalmCoA to HXOL IEA Sus scrofa 15378 R-SSC-418365 https://reactome.org/PathwayBrowser/#/R-SSC-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Sus scrofa 15378 R-SSC-425577 https://reactome.org/PathwayBrowser/#/R-SSC-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Sus scrofa 15378 R-SSC-425965 https://reactome.org/PathwayBrowser/#/R-SSC-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Sus scrofa 15378 R-SSC-425983 https://reactome.org/PathwayBrowser/#/R-SSC-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Sus scrofa 15378 R-SSC-425994 https://reactome.org/PathwayBrowser/#/R-SSC-425994 Na+/H+ exchanger transport (at cell membrane) IEA Sus scrofa 15378 R-SSC-426015 https://reactome.org/PathwayBrowser/#/R-SSC-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Sus scrofa 15378 R-SSC-426043 https://reactome.org/PathwayBrowser/#/R-SSC-426043 2-AG hydrolysis to arachidonate by MAGL IEA Sus scrofa 15378 R-SSC-427555 https://reactome.org/PathwayBrowser/#/R-SSC-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-SSC-427910 https://reactome.org/PathwayBrowser/#/R-SSC-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Sus scrofa 15378 R-SSC-427998 https://reactome.org/PathwayBrowser/#/R-SSC-427998 Proton-coupled di- and tri-peptide cotransport IEA Sus scrofa 15378 R-SSC-428007 https://reactome.org/PathwayBrowser/#/R-SSC-428007 Proton-coupled histidine and di-peptide cotransport IEA Sus scrofa 15378 R-SSC-428015 https://reactome.org/PathwayBrowser/#/R-SSC-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Sus scrofa 15378 R-SSC-428052 https://reactome.org/PathwayBrowser/#/R-SSC-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Sus scrofa 15378 R-SSC-428123 https://reactome.org/PathwayBrowser/#/R-SSC-428123 KDSR reduces 3-ketosphingoid IEA Sus scrofa 15378 R-SSC-428127 https://reactome.org/PathwayBrowser/#/R-SSC-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Sus scrofa 15378 R-SSC-428185 https://reactome.org/PathwayBrowser/#/R-SSC-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Sus scrofa 15378 R-SSC-428259 https://reactome.org/PathwayBrowser/#/R-SSC-428259 DEGS1 dehydrogenates dihydroceramide IEA Sus scrofa 15378 R-SSC-428260 https://reactome.org/PathwayBrowser/#/R-SSC-428260 DEGS2 oxygenates dihydroceramide IEA Sus scrofa 15378 R-SSC-428273 https://reactome.org/PathwayBrowser/#/R-SSC-428273 SPHK1 phosphorylates sphingoid IEA Sus scrofa 15378 R-SSC-428585 https://reactome.org/PathwayBrowser/#/R-SSC-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Sus scrofa 15378 R-SSC-428625 https://reactome.org/PathwayBrowser/#/R-SSC-428625 Vesicular inhibitory amino acid transport IEA Sus scrofa 15378 R-SSC-429101 https://reactome.org/PathwayBrowser/#/R-SSC-429101 HMIT co-transports myo-inositol with a proton IEA Sus scrofa 15378 R-SSC-429157 https://reactome.org/PathwayBrowser/#/R-SSC-429157 ABCC4 accumulation of dense granule contents IEA Sus scrofa 15378 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-SSC-434650 https://reactome.org/PathwayBrowser/#/R-SSC-434650 MATEs mediate extrusion of xenobiotics IEA Sus scrofa 15378 R-SSC-435171 https://reactome.org/PathwayBrowser/#/R-SSC-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Sus scrofa 15378 R-SSC-435349 https://reactome.org/PathwayBrowser/#/R-SSC-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-SSC-444393 https://reactome.org/PathwayBrowser/#/R-SSC-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Sus scrofa 15378 R-SSC-444419 https://reactome.org/PathwayBrowser/#/R-SSC-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Sus scrofa 15378 R-SSC-444731 https://reactome.org/PathwayBrowser/#/R-SSC-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Sus scrofa 15378 R-SSC-446277 https://reactome.org/PathwayBrowser/#/R-SSC-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Sus scrofa 15378 R-SSC-446278 https://reactome.org/PathwayBrowser/#/R-SSC-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Sus scrofa 15378 R-SSC-469659 https://reactome.org/PathwayBrowser/#/R-SSC-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Sus scrofa 15378 R-SSC-504054 https://reactome.org/PathwayBrowser/#/R-SSC-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Sus scrofa 15378 R-SSC-508040 https://reactome.org/PathwayBrowser/#/R-SSC-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Sus scrofa 15378 R-SSC-508369 https://reactome.org/PathwayBrowser/#/R-SSC-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Sus scrofa 15378 R-SSC-508473 https://reactome.org/PathwayBrowser/#/R-SSC-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Sus scrofa 15378 R-SSC-514604 https://reactome.org/PathwayBrowser/#/R-SSC-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Sus scrofa 15378 R-SSC-5218841 https://reactome.org/PathwayBrowser/#/R-SSC-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Sus scrofa 15378 R-SSC-5340130 https://reactome.org/PathwayBrowser/#/R-SSC-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Sus scrofa 15378 R-SSC-5340226 https://reactome.org/PathwayBrowser/#/R-SSC-5340226 CYGB dioxygenates NO IEA Sus scrofa 15378 R-SSC-5362518 https://reactome.org/PathwayBrowser/#/R-SSC-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Sus scrofa 15378 R-SSC-5362522 https://reactome.org/PathwayBrowser/#/R-SSC-5362522 ALDHs oxidise atRAL to atRA IEA Sus scrofa 15378 R-SSC-5362525 https://reactome.org/PathwayBrowser/#/R-SSC-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Sus scrofa 15378 R-SSC-5362564 https://reactome.org/PathwayBrowser/#/R-SSC-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Sus scrofa 15378 R-SSC-5362721 https://reactome.org/PathwayBrowser/#/R-SSC-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Sus scrofa 15378 R-SSC-5419165 https://reactome.org/PathwayBrowser/#/R-SSC-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Sus scrofa 15378 R-SSC-5423637 https://reactome.org/PathwayBrowser/#/R-SSC-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Sus scrofa 15378 R-SSC-5423647 https://reactome.org/PathwayBrowser/#/R-SSC-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Sus scrofa 15378 R-SSC-5423664 https://reactome.org/PathwayBrowser/#/R-SSC-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Sus scrofa 15378 R-SSC-5423672 https://reactome.org/PathwayBrowser/#/R-SSC-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Sus scrofa 15378 R-SSC-5423678 https://reactome.org/PathwayBrowser/#/R-SSC-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Sus scrofa 15378 R-SSC-548818 https://reactome.org/PathwayBrowser/#/R-SSC-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Sus scrofa 15378 R-SSC-548831 https://reactome.org/PathwayBrowser/#/R-SSC-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Sus scrofa 15378 R-SSC-5602295 https://reactome.org/PathwayBrowser/#/R-SSC-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Sus scrofa 15378 R-SSC-5615668 https://reactome.org/PathwayBrowser/#/R-SSC-5615668 AKR1C3 reduces atRAL to atROL IEA Sus scrofa 15378 R-SSC-5623643 https://reactome.org/PathwayBrowser/#/R-SSC-5623643 RDH13 reduces atRAL to atROL IEA Sus scrofa 15378 R-SSC-5652172 https://reactome.org/PathwayBrowser/#/R-SSC-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Sus scrofa 15378 R-SSC-5652195 https://reactome.org/PathwayBrowser/#/R-SSC-5652195 SORD oxidizes D-sorbitol to Fru IEA Sus scrofa 15378 R-SSC-5661240 https://reactome.org/PathwayBrowser/#/R-SSC-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Sus scrofa 15378 R-SSC-5661256 https://reactome.org/PathwayBrowser/#/R-SSC-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Sus scrofa 15378 R-SSC-5661290 https://reactome.org/PathwayBrowser/#/R-SSC-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Sus scrofa 15378 R-SSC-5662471 https://reactome.org/PathwayBrowser/#/R-SSC-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Sus scrofa 15378 R-SSC-5662662 https://reactome.org/PathwayBrowser/#/R-SSC-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Sus scrofa 15378 R-SSC-5668629 https://reactome.org/PathwayBrowser/#/R-SSC-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Sus scrofa 15378 R-SSC-5668718 https://reactome.org/PathwayBrowser/#/R-SSC-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 15378 R-SSC-5668731 https://reactome.org/PathwayBrowser/#/R-SSC-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 15378 R-SSC-5678327 https://reactome.org/PathwayBrowser/#/R-SSC-5678327 MIOX oxidises Ins to GlcA IEA Sus scrofa 15378 R-SSC-5690565 https://reactome.org/PathwayBrowser/#/R-SSC-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15378 R-SSC-5691107 https://reactome.org/PathwayBrowser/#/R-SSC-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Sus scrofa 15378 R-SSC-5692237 https://reactome.org/PathwayBrowser/#/R-SSC-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Sus scrofa 15378 R-SSC-5692261 https://reactome.org/PathwayBrowser/#/R-SSC-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Sus scrofa 15378 R-SSC-5692283 https://reactome.org/PathwayBrowser/#/R-SSC-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Sus scrofa 15378 R-SSC-5693347 https://reactome.org/PathwayBrowser/#/R-SSC-5693347 CRYM reduces P2C to PPCA IEA Sus scrofa 15378 R-SSC-5693390 https://reactome.org/PathwayBrowser/#/R-SSC-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Sus scrofa 15378 R-SSC-5693681 https://reactome.org/PathwayBrowser/#/R-SSC-5693681 DUOX1,2 reduce O2 to H2O2 IEA Sus scrofa 15378 R-SSC-5693691 https://reactome.org/PathwayBrowser/#/R-SSC-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Sus scrofa 15378 R-SSC-5693761 https://reactome.org/PathwayBrowser/#/R-SSC-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Sus scrofa 15378 R-SSC-5694018 https://reactome.org/PathwayBrowser/#/R-SSC-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Sus scrofa 15378 R-SSC-5694462 https://reactome.org/PathwayBrowser/#/R-SSC-5694462 ABHD6,12 hydrolyse 3AG IEA Sus scrofa 15378 R-SSC-5696080 https://reactome.org/PathwayBrowser/#/R-SSC-5696080 ALDH3B1 oxidises HXAL to PALM IEA Sus scrofa 15378 R-SSC-5696091 https://reactome.org/PathwayBrowser/#/R-SSC-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Sus scrofa 15378 R-SSC-5696101 https://reactome.org/PathwayBrowser/#/R-SSC-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Sus scrofa 15378 R-SSC-5696131 https://reactome.org/PathwayBrowser/#/R-SSC-5696131 AOC1 deaminates Hist IEA Sus scrofa 15378 R-SSC-5696146 https://reactome.org/PathwayBrowser/#/R-SSC-5696146 AOC2 deaminates TYR IEA Sus scrofa 15378 R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa 15378 R-SSC-5696457 https://reactome.org/PathwayBrowser/#/R-SSC-5696457 BDH2 dehydrogenates 3HBA IEA Sus scrofa 15378 R-SSC-5696838 https://reactome.org/PathwayBrowser/#/R-SSC-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Sus scrofa 15378 R-SSC-597628 https://reactome.org/PathwayBrowser/#/R-SSC-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Sus scrofa 15378 R-SSC-6783221 https://reactome.org/PathwayBrowser/#/R-SSC-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Sus scrofa 15378 R-SSC-6783939 https://reactome.org/PathwayBrowser/#/R-SSC-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 15378 R-SSC-6783955 https://reactome.org/PathwayBrowser/#/R-SSC-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 15378 R-SSC-6784399 https://reactome.org/PathwayBrowser/#/R-SSC-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Sus scrofa 15378 R-SSC-6785933 https://reactome.org/PathwayBrowser/#/R-SSC-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Sus scrofa 15378 R-SSC-6786239 https://reactome.org/PathwayBrowser/#/R-SSC-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Sus scrofa 15378 R-SSC-6786720 https://reactome.org/PathwayBrowser/#/R-SSC-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Sus scrofa 15378 R-SSC-6787642 https://reactome.org/PathwayBrowser/#/R-SSC-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Sus scrofa 15378 R-SSC-6788999 https://reactome.org/PathwayBrowser/#/R-SSC-6788999 HV1-mediated H+ transfer IEA Sus scrofa 15378 R-SSC-6789031 https://reactome.org/PathwayBrowser/#/R-SSC-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 15378 R-SSC-6789092 https://reactome.org/PathwayBrowser/#/R-SSC-6789092 NOX2 generates superoxide anion from oxygen IEA Sus scrofa 15378 R-SSC-6789126 https://reactome.org/PathwayBrowser/#/R-SSC-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 15378 R-SSC-6793590 https://reactome.org/PathwayBrowser/#/R-SSC-6793590 LIPT2 transfers octanoyl group to GCSH IEA Sus scrofa 15378 R-SSC-6793591 https://reactome.org/PathwayBrowser/#/R-SSC-6793591 LIAS synthesizes lipoyl-GCSH IEA Sus scrofa 15378 R-SSC-6799495 https://reactome.org/PathwayBrowser/#/R-SSC-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Sus scrofa 15378 R-SSC-6799722 https://reactome.org/PathwayBrowser/#/R-SSC-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Sus scrofa 15378 R-SSC-6801342 https://reactome.org/PathwayBrowser/#/R-SSC-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Sus scrofa 15378 R-SSC-6803771 https://reactome.org/PathwayBrowser/#/R-SSC-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Sus scrofa 15378 R-SSC-6806647 https://reactome.org/PathwayBrowser/#/R-SSC-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 15378 R-SSC-6806831 https://reactome.org/PathwayBrowser/#/R-SSC-6806831 CYB5Rs reduce MetHb to HbA IEA Sus scrofa 15378 R-SSC-6806967 https://reactome.org/PathwayBrowser/#/R-SSC-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Sus scrofa 15378 R-SSC-6807053 https://reactome.org/PathwayBrowser/#/R-SSC-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Sus scrofa 15378 R-SSC-6807055 https://reactome.org/PathwayBrowser/#/R-SSC-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Sus scrofa 15378 R-SSC-6807064 https://reactome.org/PathwayBrowser/#/R-SSC-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Sus scrofa 15378 R-SSC-6807557 https://reactome.org/PathwayBrowser/#/R-SSC-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Sus scrofa 15378 R-SSC-6808464 https://reactome.org/PathwayBrowser/#/R-SSC-6808464 ALDH3B2 oxidises HXAL to PALM IEA Sus scrofa 15378 R-SSC-6808487 https://reactome.org/PathwayBrowser/#/R-SSC-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 15378 R-SSC-6808496 https://reactome.org/PathwayBrowser/#/R-SSC-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 15378 R-SSC-6809264 https://reactome.org/PathwayBrowser/#/R-SSC-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Sus scrofa 15378 R-SSC-6809287 https://reactome.org/PathwayBrowser/#/R-SSC-6809287 NUDT12 hydrolyses NADH to NMNH IEA Sus scrofa 15378 R-SSC-6809810 https://reactome.org/PathwayBrowser/#/R-SSC-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Sus scrofa 15378 R-SSC-6813749 https://reactome.org/PathwayBrowser/#/R-SSC-6813749 ALDH1A1 oxidises GA to DGA IEA Sus scrofa 15378 R-SSC-6814153 https://reactome.org/PathwayBrowser/#/R-SSC-6814153 ADO oxidises 2AET to HTAU IEA Sus scrofa 15378 R-SSC-70333 https://reactome.org/PathwayBrowser/#/R-SSC-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Sus scrofa 15378 R-SSC-70377 https://reactome.org/PathwayBrowser/#/R-SSC-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Sus scrofa 15378 R-SSC-70420 https://reactome.org/PathwayBrowser/#/R-SSC-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Sus scrofa 15378 R-SSC-70449 https://reactome.org/PathwayBrowser/#/R-SSC-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Sus scrofa 15378 R-SSC-70467 https://reactome.org/PathwayBrowser/#/R-SSC-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Sus scrofa 15378 R-SSC-70482 https://reactome.org/PathwayBrowser/#/R-SSC-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Sus scrofa 15378 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 15378 R-SSC-70510 https://reactome.org/PathwayBrowser/#/R-SSC-70510 LDH tetramer oxidises LACT to PYR IEA Sus scrofa 15378 R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Sus scrofa 15378 R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Sus scrofa 15378 R-SSC-70664 https://reactome.org/PathwayBrowser/#/R-SSC-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 15378 R-SSC-70670 https://reactome.org/PathwayBrowser/#/R-SSC-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Sus scrofa 15378 R-SSC-70679 https://reactome.org/PathwayBrowser/#/R-SSC-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Sus scrofa 15378 R-SSC-70837 https://reactome.org/PathwayBrowser/#/R-SSC-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Sus scrofa 15378 R-SSC-70885 https://reactome.org/PathwayBrowser/#/R-SSC-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Sus scrofa 15378 R-SSC-70893 https://reactome.org/PathwayBrowser/#/R-SSC-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Sus scrofa 15378 R-SSC-70906 https://reactome.org/PathwayBrowser/#/R-SSC-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Sus scrofa 15378 R-SSC-70938 https://reactome.org/PathwayBrowser/#/R-SSC-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Sus scrofa 15378 R-SSC-70940 https://reactome.org/PathwayBrowser/#/R-SSC-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Sus scrofa 15378 R-SSC-70941 https://reactome.org/PathwayBrowser/#/R-SSC-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Sus scrofa 15378 R-SSC-70975 https://reactome.org/PathwayBrowser/#/R-SSC-70975 CS acetylates OA to citrate IEA Sus scrofa 15378 R-SSC-70979 https://reactome.org/PathwayBrowser/#/R-SSC-70979 MDH2 dimer dehydrogenates MAL IEA Sus scrofa 15378 R-SSC-71130 https://reactome.org/PathwayBrowser/#/R-SSC-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Sus scrofa 15378 R-SSC-71164 https://reactome.org/PathwayBrowser/#/R-SSC-71164 HGD dioxygenates homogentisate IEA Sus scrofa 15378 R-SSC-71181 https://reactome.org/PathwayBrowser/#/R-SSC-71181 FAH cleaves 4FAA IEA Sus scrofa 15378 R-SSC-71200 https://reactome.org/PathwayBrowser/#/R-SSC-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Sus scrofa 15378 R-SSC-71260 https://reactome.org/PathwayBrowser/#/R-SSC-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Sus scrofa 15378 R-SSC-71286 https://reactome.org/PathwayBrowser/#/R-SSC-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Sus scrofa 15378 R-SSC-71299 https://reactome.org/PathwayBrowser/#/R-SSC-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Sus scrofa 15378 R-SSC-71401 https://reactome.org/PathwayBrowser/#/R-SSC-71401 OGDH dimer decarboxylates 2-OG IEA Sus scrofa 15378 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 15378 R-SSC-71682 https://reactome.org/PathwayBrowser/#/R-SSC-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 15378 R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 15378 R-SSC-71707 https://reactome.org/PathwayBrowser/#/R-SSC-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Sus scrofa 15378 R-SSC-71723 https://reactome.org/PathwayBrowser/#/R-SSC-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Sus scrofa 15378 R-SSC-71849 https://reactome.org/PathwayBrowser/#/R-SSC-71849 LDH tetramer reduces PYR to LACT IEA Sus scrofa 15378 R-SSC-73564 https://reactome.org/PathwayBrowser/#/R-SSC-73564 UMPS dimer decarboxylates OMP to UMP IEA Sus scrofa 15378 R-SSC-73571 https://reactome.org/PathwayBrowser/#/R-SSC-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Sus scrofa 15378 R-SSC-73573 https://reactome.org/PathwayBrowser/#/R-SSC-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Sus scrofa 15378 R-SSC-73577 https://reactome.org/PathwayBrowser/#/R-SSC-73577 CAD hexamer transforms L-Gln to CAP IEA Sus scrofa 15378 R-SSC-73585 https://reactome.org/PathwayBrowser/#/R-SSC-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Sus scrofa 15378 R-SSC-73589 https://reactome.org/PathwayBrowser/#/R-SSC-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Sus scrofa 15378 R-SSC-73591 https://reactome.org/PathwayBrowser/#/R-SSC-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Sus scrofa 15378 R-SSC-73596 https://reactome.org/PathwayBrowser/#/R-SSC-73596 dCMP + H2O => dUMP + NH4+ IEA Sus scrofa 15378 R-SSC-73616 https://reactome.org/PathwayBrowser/#/R-SSC-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Sus scrofa 15378 R-SSC-73618 https://reactome.org/PathwayBrowser/#/R-SSC-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Sus scrofa 15378 R-SSC-73620 https://reactome.org/PathwayBrowser/#/R-SSC-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Sus scrofa 15378 R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa 15378 R-SSC-73666 https://reactome.org/PathwayBrowser/#/R-SSC-73666 dUTP + H2O => dUMP + pyrophosphate IEA Sus scrofa 15378 R-SSC-73792 https://reactome.org/PathwayBrowser/#/R-SSC-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Sus scrofa 15378 R-SSC-73794 https://reactome.org/PathwayBrowser/#/R-SSC-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Sus scrofa 15378 R-SSC-73805 https://reactome.org/PathwayBrowser/#/R-SSC-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Sus scrofa 15378 R-SSC-73806 https://reactome.org/PathwayBrowser/#/R-SSC-73806 AIR + CO2 => CAIR IEA Sus scrofa 15378 R-SSC-73810 https://reactome.org/PathwayBrowser/#/R-SSC-73810 FGAM + ATP => AIR + ADP + Pi IEA Sus scrofa 15378 R-SSC-73813 https://reactome.org/PathwayBrowser/#/R-SSC-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Sus scrofa 15378 R-SSC-73814 https://reactome.org/PathwayBrowser/#/R-SSC-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Sus scrofa 15378 R-SSC-73912 https://reactome.org/PathwayBrowser/#/R-SSC-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Sus scrofa 15378 R-SSC-73920 https://reactome.org/PathwayBrowser/#/R-SSC-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Sus scrofa 15378 R-SSC-74255 https://reactome.org/PathwayBrowser/#/R-SSC-74255 Guanine + H2O => Xanthine + NH4+ IEA Sus scrofa 15378 R-SSC-74723 https://reactome.org/PathwayBrowser/#/R-SSC-74723 Endosome acidification IEA Sus scrofa 15378 R-SSC-74872 https://reactome.org/PathwayBrowser/#/R-SSC-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Sus scrofa 15378 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15378 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15378 R-SSC-75872 https://reactome.org/PathwayBrowser/#/R-SSC-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Sus scrofa 15378 R-SSC-75883 https://reactome.org/PathwayBrowser/#/R-SSC-75883 DHRS7B reduces GO3P to HXDG3P IEA Sus scrofa 15378 R-SSC-75889 https://reactome.org/PathwayBrowser/#/R-SSC-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Sus scrofa 15378 R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa 15378 R-SSC-76373 https://reactome.org/PathwayBrowser/#/R-SSC-76373 N-hydroxylation of 4-aminobiphenyl IEA Sus scrofa 15378 R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 15378 R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa 15378 R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 15378 R-SSC-76453 https://reactome.org/PathwayBrowser/#/R-SSC-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Sus scrofa 15378 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 15378 R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 15378 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 15378 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 15378 R-SSC-77254 https://reactome.org/PathwayBrowser/#/R-SSC-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Sus scrofa 15378 R-SSC-77283 https://reactome.org/PathwayBrowser/#/R-SSC-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Sus scrofa 15378 R-SSC-77303 https://reactome.org/PathwayBrowser/#/R-SSC-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Sus scrofa 15378 R-SSC-77312 https://reactome.org/PathwayBrowser/#/R-SSC-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Sus scrofa 15378 R-SSC-77323 https://reactome.org/PathwayBrowser/#/R-SSC-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Sus scrofa 15378 R-SSC-77331 https://reactome.org/PathwayBrowser/#/R-SSC-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Sus scrofa 15378 R-SSC-77342 https://reactome.org/PathwayBrowser/#/R-SSC-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Sus scrofa 15378 R-SSC-804969 https://reactome.org/PathwayBrowser/#/R-SSC-804969 HSD17B1 hydrogenates E1 to EST17b IEA Sus scrofa 15378 R-SSC-8847579 https://reactome.org/PathwayBrowser/#/R-SSC-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15378 R-SSC-8849638 https://reactome.org/PathwayBrowser/#/R-SSC-8849638 Dissociation of the SPINK5:KLK5 complex at low pH IEA Sus scrofa 15378 R-SSC-8850846 https://reactome.org/PathwayBrowser/#/R-SSC-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-SSC-8850854 https://reactome.org/PathwayBrowser/#/R-SSC-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-SSC-8851110 https://reactome.org/PathwayBrowser/#/R-SSC-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-SSC-8851129 https://reactome.org/PathwayBrowser/#/R-SSC-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 15378 R-SSC-8862137 https://reactome.org/PathwayBrowser/#/R-SSC-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Sus scrofa 15378 R-SSC-8862152 https://reactome.org/PathwayBrowser/#/R-SSC-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Sus scrofa 15378 R-SSC-8863494 https://reactome.org/PathwayBrowser/#/R-SSC-8863494 ASICs bind STOML3, (STOM) IEA Sus scrofa 15378 R-SSC-8866601 https://reactome.org/PathwayBrowser/#/R-SSC-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Sus scrofa 15378 R-SSC-8869606 https://reactome.org/PathwayBrowser/#/R-SSC-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Sus scrofa 15378 R-SSC-8869607 https://reactome.org/PathwayBrowser/#/R-SSC-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Sus scrofa 15378 R-SSC-8869627 https://reactome.org/PathwayBrowser/#/R-SSC-8869627 NMRK2 phosphorylates NR to yield NMN IEA Sus scrofa 15378 R-SSC-8869633 https://reactome.org/PathwayBrowser/#/R-SSC-8869633 NMRK1 phosphorylates NR to yield NMN IEA Sus scrofa 15378 R-SSC-8870346 https://reactome.org/PathwayBrowser/#/R-SSC-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Sus scrofa 15378 R-SSC-8875623 https://reactome.org/PathwayBrowser/#/R-SSC-8875623 SLC25A18,22 import L-Glu, H+ IEA Sus scrofa 15378 R-SSC-8878914 https://reactome.org/PathwayBrowser/#/R-SSC-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Sus scrofa 15378 R-SSC-888548 https://reactome.org/PathwayBrowser/#/R-SSC-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Sus scrofa 15378 R-SSC-888572 https://reactome.org/PathwayBrowser/#/R-SSC-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Sus scrofa 15378 R-SSC-888577 https://reactome.org/PathwayBrowser/#/R-SSC-888577 Synthesis of GABA by GAD2 IEA Sus scrofa 15378 R-SSC-8933635 https://reactome.org/PathwayBrowser/#/R-SSC-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Sus scrofa 15378 R-SSC-8936442 https://reactome.org/PathwayBrowser/#/R-SSC-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Sus scrofa 15378 R-SSC-8938076 https://reactome.org/PathwayBrowser/#/R-SSC-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Sus scrofa 15378 R-SSC-8952873 https://reactome.org/PathwayBrowser/#/R-SSC-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Sus scrofa 15378 R-SSC-8954468 https://reactome.org/PathwayBrowser/#/R-SSC-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Sus scrofa 15378 R-SSC-8955030 https://reactome.org/PathwayBrowser/#/R-SSC-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Sus scrofa 15378 R-SSC-8955760 https://reactome.org/PathwayBrowser/#/R-SSC-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Sus scrofa 15378 R-SSC-8956458 https://reactome.org/PathwayBrowser/#/R-SSC-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Sus scrofa 15378 R-SSC-8959510 https://reactome.org/PathwayBrowser/#/R-SSC-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Sus scrofa 15378 R-SSC-8959719 https://reactome.org/PathwayBrowser/#/R-SSC-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Sus scrofa 15378 R-SSC-9009950 https://reactome.org/PathwayBrowser/#/R-SSC-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Sus scrofa 15378 R-SSC-9011595 https://reactome.org/PathwayBrowser/#/R-SSC-9011595 GSTZ1 dimer dehalogenates DCA IEA Sus scrofa 15378 R-SSC-9012016 https://reactome.org/PathwayBrowser/#/R-SSC-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Sus scrofa 15378 R-SSC-9012036 https://reactome.org/PathwayBrowser/#/R-SSC-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Sus scrofa 15378 R-SSC-9024993 https://reactome.org/PathwayBrowser/#/R-SSC-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Sus scrofa 15378 R-SSC-9027043 https://reactome.org/PathwayBrowser/#/R-SSC-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Sus scrofa 15378 R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 15378 R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 15378 R-SSC-9037761 https://reactome.org/PathwayBrowser/#/R-SSC-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Sus scrofa 15378 R-SSC-917811 https://reactome.org/PathwayBrowser/#/R-SSC-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Sus scrofa 15378 R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa 15378 R-SSC-917891 https://reactome.org/PathwayBrowser/#/R-SSC-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Sus scrofa 15378 R-SSC-917933 https://reactome.org/PathwayBrowser/#/R-SSC-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Sus scrofa 15378 R-SSC-917979 https://reactome.org/PathwayBrowser/#/R-SSC-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Sus scrofa 15378 R-SSC-937311 https://reactome.org/PathwayBrowser/#/R-SSC-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Sus scrofa 15378 R-SSC-9620103 https://reactome.org/PathwayBrowser/#/R-SSC-9620103 ALDH2 transforms GTN to NO IEA Sus scrofa 15378 R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-SSC-9650165 https://reactome.org/PathwayBrowser/#/R-SSC-9650165 ASIC trimers bind H+ IEA Sus scrofa 15378 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 15378 R-SSC-9705713 https://reactome.org/PathwayBrowser/#/R-SSC-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Sus scrofa 15378 R-SSC-9705714 https://reactome.org/PathwayBrowser/#/R-SSC-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Sus scrofa 15378 R-SSC-9709098 https://reactome.org/PathwayBrowser/#/R-SSC-9709098 DHFR dimer reduces FOLA to DHF IEA Sus scrofa 15378 R-SSC-9727198 https://reactome.org/PathwayBrowser/#/R-SSC-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Sus scrofa 15378 R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 15378 R-SSC-9727349 https://reactome.org/PathwayBrowser/#/R-SSC-9727349 XDH dehydrogenates xanthine to form urate IEA Sus scrofa 15378 R-SSC-9731228 https://reactome.org/PathwayBrowser/#/R-SSC-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Sus scrofa 15378 R-SSC-9731590 https://reactome.org/PathwayBrowser/#/R-SSC-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Sus scrofa 15378 R-SSC-9731613 https://reactome.org/PathwayBrowser/#/R-SSC-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Sus scrofa 15378 R-SSC-9731632 https://reactome.org/PathwayBrowser/#/R-SSC-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Sus scrofa 15378 R-SSC-9731661 https://reactome.org/PathwayBrowser/#/R-SSC-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Sus scrofa 15378 R-SSC-9748945 https://reactome.org/PathwayBrowser/#/R-SSC-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Sus scrofa 15378 R-SSC-9748957 https://reactome.org/PathwayBrowser/#/R-SSC-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Sus scrofa 15378 R-SSC-9748979 https://reactome.org/PathwayBrowser/#/R-SSC-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Sus scrofa 15378 R-SSC-9748983 https://reactome.org/PathwayBrowser/#/R-SSC-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Sus scrofa 15378 R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 15378 R-SSC-9749792 https://reactome.org/PathwayBrowser/#/R-SSC-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Sus scrofa 15378 R-SSC-9753285 https://reactome.org/PathwayBrowser/#/R-SSC-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Sus scrofa 15378 R-SSC-9755937 https://reactome.org/PathwayBrowser/#/R-SSC-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Sus scrofa 15378 R-SSC-9756134 https://reactome.org/PathwayBrowser/#/R-SSC-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Sus scrofa 15378 R-SSC-9756138 https://reactome.org/PathwayBrowser/#/R-SSC-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Sus scrofa 15378 R-SSC-9756156 https://reactome.org/PathwayBrowser/#/R-SSC-9756156 UGT1A3 lactonizes ATV to ATVL IEA Sus scrofa 15378 R-SSC-9756162 https://reactome.org/PathwayBrowser/#/R-SSC-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Sus scrofa 15378 R-SSC-9756169 https://reactome.org/PathwayBrowser/#/R-SSC-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Sus scrofa 15378 R-SSC-9756177 https://reactome.org/PathwayBrowser/#/R-SSC-9756177 PON1,3 hydrolyse ATVL to ATV IEA Sus scrofa 15378 R-SSC-9756180 https://reactome.org/PathwayBrowser/#/R-SSC-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Sus scrofa 15378 R-SSC-9756183 https://reactome.org/PathwayBrowser/#/R-SSC-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Sus scrofa 15378 R-SSC-975629 https://reactome.org/PathwayBrowser/#/R-SSC-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Sus scrofa 15378 R-SSC-9757706 https://reactome.org/PathwayBrowser/#/R-SSC-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Sus scrofa 15378 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 15378 R-SSC-9758674 https://reactome.org/PathwayBrowser/#/R-SSC-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Sus scrofa 15378 R-SSC-9758682 https://reactome.org/PathwayBrowser/#/R-SSC-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Sus scrofa 15378 R-SSC-9759259 https://reactome.org/PathwayBrowser/#/R-SSC-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Sus scrofa 15378 R-SSC-9759549 https://reactome.org/PathwayBrowser/#/R-SSC-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Sus scrofa 15378 R-SSC-9760094 https://reactome.org/PathwayBrowser/#/R-SSC-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Sus scrofa 15378 R-SSC-977348 https://reactome.org/PathwayBrowser/#/R-SSC-977348 PHGDH tetramer dehydrogenates 3PG IEA Sus scrofa 15378 R-SSC-9794270 https://reactome.org/PathwayBrowser/#/R-SSC-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Sus scrofa 15378 R-SSC-9837337 https://reactome.org/PathwayBrowser/#/R-SSC-9837337 DCAKD phosphorylates DP-CoA IEA Sus scrofa 15378 R-SSC-9843721 https://reactome.org/PathwayBrowser/#/R-SSC-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Sus scrofa 15378 R-SSC-9844587 https://reactome.org/PathwayBrowser/#/R-SSC-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Sus scrofa 15378 R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 15378 R-SSC-9845516 https://reactome.org/PathwayBrowser/#/R-SSC-9845516 B3GALT4 transfers Gal to gangliosides IEA Sus scrofa 15378 R-SSC-9845538 https://reactome.org/PathwayBrowser/#/R-SSC-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Sus scrofa 15378 R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 15378 R-SSC-9846305 https://reactome.org/PathwayBrowser/#/R-SSC-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Sus scrofa 15378 R-SSC-9846332 https://reactome.org/PathwayBrowser/#/R-SSC-9846332 FUT1,2 transfer fucose to gangliosides IEA Sus scrofa 15378 R-SSC-9846477 https://reactome.org/PathwayBrowser/#/R-SSC-9846477 A4GALT transfers galactose to LacCer IEA Sus scrofa 15378 R-SSC-9846501 https://reactome.org/PathwayBrowser/#/R-SSC-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Sus scrofa 15378 R-SSC-9851347 https://reactome.org/PathwayBrowser/#/R-SSC-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Sus scrofa 15378 R-SSC-9853499 https://reactome.org/PathwayBrowser/#/R-SSC-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 15378 R-SSC-9854315 https://reactome.org/PathwayBrowser/#/R-SSC-9854315 CSKMT methylates Citrate Synthase IEA Sus scrofa 15378 R-SSC-9854415 https://reactome.org/PathwayBrowser/#/R-SSC-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Sus scrofa 15378 R-SSC-9856871 https://reactome.org/PathwayBrowser/#/R-SSC-9856871 MDH1 reduces OA IEA Sus scrofa 15378 R-SSC-9861616 https://reactome.org/PathwayBrowser/#/R-SSC-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 15378 R-SSC-9861642 https://reactome.org/PathwayBrowser/#/R-SSC-9861642 NEK1 phosphorylates ME1 IEA Sus scrofa 15378 R-SSC-9861660 https://reactome.org/PathwayBrowser/#/R-SSC-9861660 ME1 tetramer decarboxylates OA to PYR IEA Sus scrofa 15378 R-SSC-9861734 https://reactome.org/PathwayBrowser/#/R-SSC-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Sus scrofa 15378 R-XTR-109343 https://reactome.org/PathwayBrowser/#/R-XTR-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Xenopus tropicalis 15378 R-XTR-111524 https://reactome.org/PathwayBrowser/#/R-XTR-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Xenopus tropicalis 15378 R-XTR-1222376 https://reactome.org/PathwayBrowser/#/R-XTR-1222376 NOX2 generates superoxide from oxygen IEA Xenopus tropicalis 15378 R-XTR-1222516 https://reactome.org/PathwayBrowser/#/R-XTR-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Xenopus tropicalis 15378 R-XTR-1236967 https://reactome.org/PathwayBrowser/#/R-XTR-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Xenopus tropicalis 15378 R-XTR-1237047 https://reactome.org/PathwayBrowser/#/R-XTR-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Xenopus tropicalis 15378 R-XTR-1237059 https://reactome.org/PathwayBrowser/#/R-XTR-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Xenopus tropicalis 15378 R-XTR-1237129 https://reactome.org/PathwayBrowser/#/R-XTR-1237129 Acireductone is created IEA Xenopus tropicalis 15378 R-XTR-1237325 https://reactome.org/PathwayBrowser/#/R-XTR-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Xenopus tropicalis 15378 R-XTR-1247668 https://reactome.org/PathwayBrowser/#/R-XTR-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Xenopus tropicalis 15378 R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 15378 R-XTR-140359 https://reactome.org/PathwayBrowser/#/R-XTR-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Xenopus tropicalis 15378 R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 15378 R-XTR-1475017 https://reactome.org/PathwayBrowser/#/R-XTR-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Xenopus tropicalis 15378 R-XTR-1475022 https://reactome.org/PathwayBrowser/#/R-XTR-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Xenopus tropicalis 15378 R-XTR-1475025 https://reactome.org/PathwayBrowser/#/R-XTR-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Xenopus tropicalis 15378 R-XTR-1475026 https://reactome.org/PathwayBrowser/#/R-XTR-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Xenopus tropicalis 15378 R-XTR-1475028 https://reactome.org/PathwayBrowser/#/R-XTR-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Xenopus tropicalis 15378 R-XTR-1475032 https://reactome.org/PathwayBrowser/#/R-XTR-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Xenopus tropicalis 15378 R-XTR-1475435 https://reactome.org/PathwayBrowser/#/R-XTR-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Xenopus tropicalis 15378 R-XTR-1475436 https://reactome.org/PathwayBrowser/#/R-XTR-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Xenopus tropicalis 15378 R-XTR-1497869 https://reactome.org/PathwayBrowser/#/R-XTR-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Xenopus tropicalis 15378 R-XTR-1562626 https://reactome.org/PathwayBrowser/#/R-XTR-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Xenopus tropicalis 15378 R-XTR-156526 https://reactome.org/PathwayBrowser/#/R-XTR-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 15378 R-XTR-158609 https://reactome.org/PathwayBrowser/#/R-XTR-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Xenopus tropicalis 15378 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 15378 R-XTR-1605797 https://reactome.org/PathwayBrowser/#/R-XTR-1605797 SMPD1 hydrolyzes SPHM IEA Xenopus tropicalis 15378 R-XTR-1606273 https://reactome.org/PathwayBrowser/#/R-XTR-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Xenopus tropicalis 15378 R-XTR-1614362 https://reactome.org/PathwayBrowser/#/R-XTR-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Xenopus tropicalis 15378 R-XTR-1614605 https://reactome.org/PathwayBrowser/#/R-XTR-1614605 Persulfide sulfur is dioxygenated IEA Xenopus tropicalis 15378 R-XTR-162730 https://reactome.org/PathwayBrowser/#/R-XTR-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Xenopus tropicalis 15378 R-XTR-163214 https://reactome.org/PathwayBrowser/#/R-XTR-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Xenopus tropicalis 15378 R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Xenopus tropicalis 15378 R-XTR-1638104 https://reactome.org/PathwayBrowser/#/R-XTR-1638104 UGCG transfers glucose to ceramide IEA Xenopus tropicalis 15378 R-XTR-1638845 https://reactome.org/PathwayBrowser/#/R-XTR-1638845 CERK phosphorylates CERA to form C1P IEA Xenopus tropicalis 15378 R-XTR-1640164 https://reactome.org/PathwayBrowser/#/R-XTR-1640164 ENPP7 hydrolyzes sphingomyelin IEA Xenopus tropicalis 15378 R-XTR-1655453 https://reactome.org/PathwayBrowser/#/R-XTR-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Xenopus tropicalis 15378 R-XTR-1655879 https://reactome.org/PathwayBrowser/#/R-XTR-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Xenopus tropicalis 15378 R-XTR-170026 https://reactome.org/PathwayBrowser/#/R-XTR-170026 Protons are translocated from the intermembrane space to the matrix IEA Xenopus tropicalis 15378 R-XTR-173597 https://reactome.org/PathwayBrowser/#/R-XTR-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Xenopus tropicalis 15378 R-XTR-174389 https://reactome.org/PathwayBrowser/#/R-XTR-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Xenopus tropicalis 15378 R-XTR-174392 https://reactome.org/PathwayBrowser/#/R-XTR-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Xenopus tropicalis 15378 R-XTR-189421 https://reactome.org/PathwayBrowser/#/R-XTR-189421 CPO transforms COPRO3 to PPGEN9 IEA Xenopus tropicalis 15378 R-XTR-189425 https://reactome.org/PathwayBrowser/#/R-XTR-189425 UROD decarboxylates URO3 to COPRO3 IEA Xenopus tropicalis 15378 R-XTR-189439 https://reactome.org/PathwayBrowser/#/R-XTR-189439 ALAD condenses 2 dALAs to form PBG IEA Xenopus tropicalis 15378 R-XTR-189442 https://reactome.org/PathwayBrowser/#/R-XTR-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Xenopus tropicalis 15378 R-XTR-190182 https://reactome.org/PathwayBrowser/#/R-XTR-190182 UROD decarboxylates URO1 to COPRO1 IEA Xenopus tropicalis 15378 R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 15378 R-XTR-191352 https://reactome.org/PathwayBrowser/#/R-XTR-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Xenopus tropicalis 15378 R-XTR-191402 https://reactome.org/PathwayBrowser/#/R-XTR-191402 Reduction of presqualene diphosphate to form squalene IEA Xenopus tropicalis 15378 R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 15378 R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 15378 R-XTR-192033 https://reactome.org/PathwayBrowser/#/R-XTR-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Xenopus tropicalis 15378 R-XTR-192036 https://reactome.org/PathwayBrowser/#/R-XTR-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Xenopus tropicalis 15378 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 15378 R-XTR-192061 https://reactome.org/PathwayBrowser/#/R-XTR-192061 CYP46A1 24-hydroxylates CHOL IEA Xenopus tropicalis 15378 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 15378 R-XTR-192067 https://reactome.org/PathwayBrowser/#/R-XTR-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Xenopus tropicalis 15378 R-XTR-192097 https://reactome.org/PathwayBrowser/#/R-XTR-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Xenopus tropicalis 15378 R-XTR-192157 https://reactome.org/PathwayBrowser/#/R-XTR-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Xenopus tropicalis 15378 R-XTR-192160 https://reactome.org/PathwayBrowser/#/R-XTR-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Xenopus tropicalis 15378 R-XTR-192178 https://reactome.org/PathwayBrowser/#/R-XTR-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Xenopus tropicalis 15378 R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 15378 R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 15378 R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 15378 R-XTR-193068 https://reactome.org/PathwayBrowser/#/R-XTR-193068 CYP17A1 17-hydroxylates PREG IEA Xenopus tropicalis 15378 R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 15378 R-XTR-193072 https://reactome.org/PathwayBrowser/#/R-XTR-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Xenopus tropicalis 15378 R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 15378 R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 15378 R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 15378 R-XTR-193709 https://reactome.org/PathwayBrowser/#/R-XTR-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Xenopus tropicalis 15378 R-XTR-193746 https://reactome.org/PathwayBrowser/#/R-XTR-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 15378 R-XTR-193755 https://reactome.org/PathwayBrowser/#/R-XTR-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Xenopus tropicalis 15378 R-XTR-193758 https://reactome.org/PathwayBrowser/#/R-XTR-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Xenopus tropicalis 15378 R-XTR-193781 https://reactome.org/PathwayBrowser/#/R-XTR-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Xenopus tropicalis 15378 R-XTR-193789 https://reactome.org/PathwayBrowser/#/R-XTR-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 15378 R-XTR-193800 https://reactome.org/PathwayBrowser/#/R-XTR-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Xenopus tropicalis 15378 R-XTR-193816 https://reactome.org/PathwayBrowser/#/R-XTR-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Xenopus tropicalis 15378 R-XTR-193821 https://reactome.org/PathwayBrowser/#/R-XTR-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Xenopus tropicalis 15378 R-XTR-193824 https://reactome.org/PathwayBrowser/#/R-XTR-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Xenopus tropicalis 15378 R-XTR-193841 https://reactome.org/PathwayBrowser/#/R-XTR-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Xenopus tropicalis 15378 R-XTR-193845 https://reactome.org/PathwayBrowser/#/R-XTR-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Xenopus tropicalis 15378 R-XTR-193965 https://reactome.org/PathwayBrowser/#/R-XTR-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Xenopus tropicalis 15378 R-XTR-193995 https://reactome.org/PathwayBrowser/#/R-XTR-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Xenopus tropicalis 15378 R-XTR-193997 https://reactome.org/PathwayBrowser/#/R-XTR-193997 CYP11B1 oxidises 11DCORT IEA Xenopus tropicalis 15378 R-XTR-194017 https://reactome.org/PathwayBrowser/#/R-XTR-194017 CYP11B2 oxidises 11DCORST to CORST IEA Xenopus tropicalis 15378 R-XTR-194023 https://reactome.org/PathwayBrowser/#/R-XTR-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Xenopus tropicalis 15378 R-XTR-194641 https://reactome.org/PathwayBrowser/#/R-XTR-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 15378 R-XTR-194669 https://reactome.org/PathwayBrowser/#/R-XTR-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 15378 R-XTR-194674 https://reactome.org/PathwayBrowser/#/R-XTR-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Xenopus tropicalis 15378 R-XTR-195664 https://reactome.org/PathwayBrowser/#/R-XTR-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Xenopus tropicalis 15378 R-XTR-196060 https://reactome.org/PathwayBrowser/#/R-XTR-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Xenopus tropicalis 15378 R-XTR-196402 https://reactome.org/PathwayBrowser/#/R-XTR-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Xenopus tropicalis 15378 R-XTR-196417 https://reactome.org/PathwayBrowser/#/R-XTR-196417 Reduction of desmosterol to cholesterol IEA Xenopus tropicalis 15378 R-XTR-196753 https://reactome.org/PathwayBrowser/#/R-XTR-196753 2xPPCS ligates PPanK with Cys IEA Xenopus tropicalis 15378 R-XTR-196754 https://reactome.org/PathwayBrowser/#/R-XTR-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Xenopus tropicalis 15378 R-XTR-196773 https://reactome.org/PathwayBrowser/#/R-XTR-196773 COASY phosphorylates DP-CoA IEA Xenopus tropicalis 15378 R-XTR-196840 https://reactome.org/PathwayBrowser/#/R-XTR-196840 3xPPCDC:3FMN decarboxylates PPC IEA Xenopus tropicalis 15378 R-XTR-196857 https://reactome.org/PathwayBrowser/#/R-XTR-196857 PANK2 phosphorylates PanK IEA Xenopus tropicalis 15378 R-XTR-196955 https://reactome.org/PathwayBrowser/#/R-XTR-196955 2xENPP1 hydrolyzes FAD to FMN IEA Xenopus tropicalis 15378 R-XTR-196964 https://reactome.org/PathwayBrowser/#/R-XTR-196964 RFK:Mg2+ phosphorylates RIB IEA Xenopus tropicalis 15378 R-XTR-197268 https://reactome.org/PathwayBrowser/#/R-XTR-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Xenopus tropicalis 15378 R-XTR-198824 https://reactome.org/PathwayBrowser/#/R-XTR-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Xenopus tropicalis 15378 R-XTR-200644 https://reactome.org/PathwayBrowser/#/R-XTR-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Xenopus tropicalis 15378 R-XTR-200676 https://reactome.org/PathwayBrowser/#/R-XTR-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Xenopus tropicalis 15378 R-XTR-200718 https://reactome.org/PathwayBrowser/#/R-XTR-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Xenopus tropicalis 15378 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 15378 R-XTR-204617 https://reactome.org/PathwayBrowser/#/R-XTR-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Xenopus tropicalis 15378 R-XTR-204647 https://reactome.org/PathwayBrowser/#/R-XTR-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Xenopus tropicalis 15378 R-XTR-204662 https://reactome.org/PathwayBrowser/#/R-XTR-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Xenopus tropicalis 15378 R-XTR-209821 https://reactome.org/PathwayBrowser/#/R-XTR-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Xenopus tropicalis 15378 R-XTR-209845 https://reactome.org/PathwayBrowser/#/R-XTR-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Xenopus tropicalis 15378 R-XTR-210404 https://reactome.org/PathwayBrowser/#/R-XTR-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Xenopus tropicalis 15378 R-XTR-211873 https://reactome.org/PathwayBrowser/#/R-XTR-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Xenopus tropicalis 15378 R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 15378 R-XTR-211881 https://reactome.org/PathwayBrowser/#/R-XTR-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Xenopus tropicalis 15378 R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 15378 R-XTR-211904 https://reactome.org/PathwayBrowser/#/R-XTR-211904 CYP4F12 18-hydroxylates ARA IEA Xenopus tropicalis 15378 R-XTR-211919 https://reactome.org/PathwayBrowser/#/R-XTR-211919 CYP4F8 19-hydroxylates PGH2 IEA Xenopus tropicalis 15378 R-XTR-211923 https://reactome.org/PathwayBrowser/#/R-XTR-211923 CYP26C1 4-hydroxylates 9cRA IEA Xenopus tropicalis 15378 R-XTR-211924 https://reactome.org/PathwayBrowser/#/R-XTR-211924 CYP4B1 12-hydroxylates ARA IEA Xenopus tropicalis 15378 R-XTR-211948 https://reactome.org/PathwayBrowser/#/R-XTR-211948 CYP3A4 can N-demethylate loperamide IEA Xenopus tropicalis 15378 R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 15378 R-XTR-211960 https://reactome.org/PathwayBrowser/#/R-XTR-211960 CYP2U1 19-hydroxylates ARA IEA Xenopus tropicalis 15378 R-XTR-211962 https://reactome.org/PathwayBrowser/#/R-XTR-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Xenopus tropicalis 15378 R-XTR-211966 https://reactome.org/PathwayBrowser/#/R-XTR-211966 CYP2D6 4-hydroxylates debrisoquine IEA Xenopus tropicalis 15378 R-XTR-211968 https://reactome.org/PathwayBrowser/#/R-XTR-211968 CYP2W1 oxidises INDOL IEA Xenopus tropicalis 15378 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 15378 R-XTR-211991 https://reactome.org/PathwayBrowser/#/R-XTR-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Xenopus tropicalis 15378 R-XTR-212005 https://reactome.org/PathwayBrowser/#/R-XTR-212005 CYP2F1 dehydrogenates 3-methylindole IEA Xenopus tropicalis 15378 R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 15378 R-XTR-213175 https://reactome.org/PathwayBrowser/#/R-XTR-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 15378 R-XTR-215526 https://reactome.org/PathwayBrowser/#/R-XTR-215526 CYP4F3 20-hydroxylates LTB4 IEA Xenopus tropicalis 15378 R-XTR-2161187 https://reactome.org/PathwayBrowser/#/R-XTR-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Xenopus tropicalis 15378 R-XTR-2161549 https://reactome.org/PathwayBrowser/#/R-XTR-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Xenopus tropicalis 15378 R-XTR-2161614 https://reactome.org/PathwayBrowser/#/R-XTR-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Xenopus tropicalis 15378 R-XTR-2161651 https://reactome.org/PathwayBrowser/#/R-XTR-2161651 PGE2 is converted to PGF2a by CBR1 IEA Xenopus tropicalis 15378 R-XTR-2161745 https://reactome.org/PathwayBrowser/#/R-XTR-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 15378 R-XTR-2161779 https://reactome.org/PathwayBrowser/#/R-XTR-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Xenopus tropicalis 15378 R-XTR-2161792 https://reactome.org/PathwayBrowser/#/R-XTR-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 15378 R-XTR-2161814 https://reactome.org/PathwayBrowser/#/R-XTR-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Xenopus tropicalis 15378 R-XTR-2161890 https://reactome.org/PathwayBrowser/#/R-XTR-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Xenopus tropicalis 15378 R-XTR-2161899 https://reactome.org/PathwayBrowser/#/R-XTR-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Xenopus tropicalis 15378 R-XTR-2161940 https://reactome.org/PathwayBrowser/#/R-XTR-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Xenopus tropicalis 15378 R-XTR-2161951 https://reactome.org/PathwayBrowser/#/R-XTR-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Xenopus tropicalis 15378 R-XTR-2162078 https://reactome.org/PathwayBrowser/#/R-XTR-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Xenopus tropicalis 15378 R-XTR-2162186 https://reactome.org/PathwayBrowser/#/R-XTR-2162186 COQ3 methylates DeMQ10H2 IEA Xenopus tropicalis 15378 R-XTR-2162188 https://reactome.org/PathwayBrowser/#/R-XTR-2162188 COQ5 methylates MDMQ10H2 IEA Xenopus tropicalis 15378 R-XTR-2162193 https://reactome.org/PathwayBrowser/#/R-XTR-2162193 COQ3 methylates DHDB IEA Xenopus tropicalis 15378 R-XTR-2162194 https://reactome.org/PathwayBrowser/#/R-XTR-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Xenopus tropicalis 15378 R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 15378 R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 15378 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 15378 R-XTR-2395512 https://reactome.org/PathwayBrowser/#/R-XTR-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Xenopus tropicalis 15378 R-XTR-2395517 https://reactome.org/PathwayBrowser/#/R-XTR-2395517 NADPH transfers electrons to FDXR IEA Xenopus tropicalis 15378 R-XTR-2395818 https://reactome.org/PathwayBrowser/#/R-XTR-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Xenopus tropicalis 15378 R-XTR-2395849 https://reactome.org/PathwayBrowser/#/R-XTR-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 15378 R-XTR-2395869 https://reactome.org/PathwayBrowser/#/R-XTR-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 15378 R-XTR-2395872 https://reactome.org/PathwayBrowser/#/R-XTR-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Xenopus tropicalis 15378 R-XTR-2395873 https://reactome.org/PathwayBrowser/#/R-XTR-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Xenopus tropicalis 15378 R-XTR-2395876 https://reactome.org/PathwayBrowser/#/R-XTR-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 15378 R-XTR-2395879 https://reactome.org/PathwayBrowser/#/R-XTR-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 15378 R-XTR-2395965 https://reactome.org/PathwayBrowser/#/R-XTR-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Xenopus tropicalis 15378 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 15378 R-XTR-2454081 https://reactome.org/PathwayBrowser/#/R-XTR-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Xenopus tropicalis 15378 R-XTR-2465940 https://reactome.org/PathwayBrowser/#/R-XTR-2465940 atRAL is reduced to atROL IEA Xenopus tropicalis 15378 R-XTR-2509793 https://reactome.org/PathwayBrowser/#/R-XTR-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Xenopus tropicalis 15378 R-XTR-2509816 https://reactome.org/PathwayBrowser/#/R-XTR-2509816 NUDT16 hydrolyses IDP to IMP IEA Xenopus tropicalis 15378 R-XTR-2509827 https://reactome.org/PathwayBrowser/#/R-XTR-2509827 ITPA hydrolyses ITP to IMP IEA Xenopus tropicalis 15378 R-XTR-2509831 https://reactome.org/PathwayBrowser/#/R-XTR-2509831 ITPA hydrolyses XTP to XMP IEA Xenopus tropicalis 15378 R-XTR-2509838 https://reactome.org/PathwayBrowser/#/R-XTR-2509838 ITPA hydrolyses dITP to dIMP IEA Xenopus tropicalis 15378 R-XTR-2534378 https://reactome.org/PathwayBrowser/#/R-XTR-2534378 Hv1 Mediated H+ Permeability IEA Xenopus tropicalis 15378 R-XTR-264615 https://reactome.org/PathwayBrowser/#/R-XTR-264615 Loading of acetylcholine in synaptic vesicles IEA Xenopus tropicalis 15378 R-XTR-2671885 https://reactome.org/PathwayBrowser/#/R-XTR-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Xenopus tropicalis 15378 R-XTR-2730692 https://reactome.org/PathwayBrowser/#/R-XTR-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Xenopus tropicalis 15378 R-XTR-2730959 https://reactome.org/PathwayBrowser/#/R-XTR-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Xenopus tropicalis 15378 R-XTR-2855252 https://reactome.org/PathwayBrowser/#/R-XTR-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Xenopus tropicalis 15378 R-XTR-2872444 https://reactome.org/PathwayBrowser/#/R-XTR-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Xenopus tropicalis 15378 R-XTR-2889070 https://reactome.org/PathwayBrowser/#/R-XTR-2889070 SLC9B2 exchanges Na+ for H+ IEA Xenopus tropicalis 15378 R-XTR-3095889 https://reactome.org/PathwayBrowser/#/R-XTR-3095889 MMACHC dealkylates RCbl IEA Xenopus tropicalis 15378 R-XTR-3149519 https://reactome.org/PathwayBrowser/#/R-XTR-3149519 MMACHC decyanates CNCbl IEA Xenopus tropicalis 15378 R-XTR-3159253 https://reactome.org/PathwayBrowser/#/R-XTR-3159253 MMAB adenosylates cob(I)alamin IEA Xenopus tropicalis 15378 R-XTR-3299680 https://reactome.org/PathwayBrowser/#/R-XTR-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Xenopus tropicalis 15378 R-XTR-3299682 https://reactome.org/PathwayBrowser/#/R-XTR-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Xenopus tropicalis 15378 R-XTR-3299691 https://reactome.org/PathwayBrowser/#/R-XTR-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Xenopus tropicalis 15378 R-XTR-3323079 https://reactome.org/PathwayBrowser/#/R-XTR-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 15378 R-XTR-352174 https://reactome.org/PathwayBrowser/#/R-XTR-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Xenopus tropicalis 15378 R-XTR-352182 https://reactome.org/PathwayBrowser/#/R-XTR-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Xenopus tropicalis 15378 R-XTR-372448 https://reactome.org/PathwayBrowser/#/R-XTR-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Xenopus tropicalis 15378 R-XTR-373867 https://reactome.org/PathwayBrowser/#/R-XTR-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-XTR-373875 https://reactome.org/PathwayBrowser/#/R-XTR-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Xenopus tropicalis 15378 R-XTR-375405 https://reactome.org/PathwayBrowser/#/R-XTR-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-XTR-375417 https://reactome.org/PathwayBrowser/#/R-XTR-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Xenopus tropicalis 15378 R-XTR-3777112 https://reactome.org/PathwayBrowser/#/R-XTR-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Xenopus tropicalis 15378 R-XTR-380608 https://reactome.org/PathwayBrowser/#/R-XTR-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Xenopus tropicalis 15378 R-XTR-389540 https://reactome.org/PathwayBrowser/#/R-XTR-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 15378 R-XTR-389550 https://reactome.org/PathwayBrowser/#/R-XTR-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 15378 R-XTR-389826 https://reactome.org/PathwayBrowser/#/R-XTR-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Xenopus tropicalis 15378 R-XTR-418365 https://reactome.org/PathwayBrowser/#/R-XTR-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Xenopus tropicalis 15378 R-XTR-425577 https://reactome.org/PathwayBrowser/#/R-XTR-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Xenopus tropicalis 15378 R-XTR-425965 https://reactome.org/PathwayBrowser/#/R-XTR-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Xenopus tropicalis 15378 R-XTR-425983 https://reactome.org/PathwayBrowser/#/R-XTR-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Xenopus tropicalis 15378 R-XTR-425994 https://reactome.org/PathwayBrowser/#/R-XTR-425994 Na+/H+ exchanger transport (at cell membrane) IEA Xenopus tropicalis 15378 R-XTR-426015 https://reactome.org/PathwayBrowser/#/R-XTR-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Xenopus tropicalis 15378 R-XTR-426043 https://reactome.org/PathwayBrowser/#/R-XTR-426043 2-AG hydrolysis to arachidonate by MAGL IEA Xenopus tropicalis 15378 R-XTR-427555 https://reactome.org/PathwayBrowser/#/R-XTR-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-XTR-427910 https://reactome.org/PathwayBrowser/#/R-XTR-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Xenopus tropicalis 15378 R-XTR-427998 https://reactome.org/PathwayBrowser/#/R-XTR-427998 Proton-coupled di- and tri-peptide cotransport IEA Xenopus tropicalis 15378 R-XTR-428007 https://reactome.org/PathwayBrowser/#/R-XTR-428007 Proton-coupled histidine and di-peptide cotransport IEA Xenopus tropicalis 15378 R-XTR-428015 https://reactome.org/PathwayBrowser/#/R-XTR-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-XTR-428052 https://reactome.org/PathwayBrowser/#/R-XTR-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Xenopus tropicalis 15378 R-XTR-428123 https://reactome.org/PathwayBrowser/#/R-XTR-428123 KDSR reduces 3-ketosphingoid IEA Xenopus tropicalis 15378 R-XTR-428127 https://reactome.org/PathwayBrowser/#/R-XTR-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Xenopus tropicalis 15378 R-XTR-428185 https://reactome.org/PathwayBrowser/#/R-XTR-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Xenopus tropicalis 15378 R-XTR-428259 https://reactome.org/PathwayBrowser/#/R-XTR-428259 DEGS1 dehydrogenates dihydroceramide IEA Xenopus tropicalis 15378 R-XTR-428260 https://reactome.org/PathwayBrowser/#/R-XTR-428260 DEGS2 oxygenates dihydroceramide IEA Xenopus tropicalis 15378 R-XTR-428585 https://reactome.org/PathwayBrowser/#/R-XTR-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Xenopus tropicalis 15378 R-XTR-429101 https://reactome.org/PathwayBrowser/#/R-XTR-429101 HMIT co-transports myo-inositol with a proton IEA Xenopus tropicalis 15378 R-XTR-434650 https://reactome.org/PathwayBrowser/#/R-XTR-434650 MATEs mediate extrusion of xenobiotics IEA Xenopus tropicalis 15378 R-XTR-435171 https://reactome.org/PathwayBrowser/#/R-XTR-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Xenopus tropicalis 15378 R-XTR-435349 https://reactome.org/PathwayBrowser/#/R-XTR-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-XTR-444393 https://reactome.org/PathwayBrowser/#/R-XTR-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Xenopus tropicalis 15378 R-XTR-444419 https://reactome.org/PathwayBrowser/#/R-XTR-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Xenopus tropicalis 15378 R-XTR-444731 https://reactome.org/PathwayBrowser/#/R-XTR-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Xenopus tropicalis 15378 R-XTR-446277 https://reactome.org/PathwayBrowser/#/R-XTR-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Xenopus tropicalis 15378 R-XTR-446278 https://reactome.org/PathwayBrowser/#/R-XTR-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Xenopus tropicalis 15378 R-XTR-450971 https://reactome.org/PathwayBrowser/#/R-XTR-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Xenopus tropicalis 15378 R-XTR-469659 https://reactome.org/PathwayBrowser/#/R-XTR-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 15378 R-XTR-508040 https://reactome.org/PathwayBrowser/#/R-XTR-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Xenopus tropicalis 15378 R-XTR-508369 https://reactome.org/PathwayBrowser/#/R-XTR-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Xenopus tropicalis 15378 R-XTR-508473 https://reactome.org/PathwayBrowser/#/R-XTR-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Xenopus tropicalis 15378 R-XTR-514604 https://reactome.org/PathwayBrowser/#/R-XTR-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Xenopus tropicalis 15378 R-XTR-5218841 https://reactome.org/PathwayBrowser/#/R-XTR-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Xenopus tropicalis 15378 R-XTR-5340226 https://reactome.org/PathwayBrowser/#/R-XTR-5340226 CYGB dioxygenates NO IEA Xenopus tropicalis 15378 R-XTR-5362518 https://reactome.org/PathwayBrowser/#/R-XTR-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Xenopus tropicalis 15378 R-XTR-5362522 https://reactome.org/PathwayBrowser/#/R-XTR-5362522 ALDHs oxidise atRAL to atRA IEA Xenopus tropicalis 15378 R-XTR-5362525 https://reactome.org/PathwayBrowser/#/R-XTR-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Xenopus tropicalis 15378 R-XTR-5362564 https://reactome.org/PathwayBrowser/#/R-XTR-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Xenopus tropicalis 15378 R-XTR-5362721 https://reactome.org/PathwayBrowser/#/R-XTR-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 15378 R-XTR-5419165 https://reactome.org/PathwayBrowser/#/R-XTR-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Xenopus tropicalis 15378 R-XTR-5423647 https://reactome.org/PathwayBrowser/#/R-XTR-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Xenopus tropicalis 15378 R-XTR-5423664 https://reactome.org/PathwayBrowser/#/R-XTR-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Xenopus tropicalis 15378 R-XTR-5423672 https://reactome.org/PathwayBrowser/#/R-XTR-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Xenopus tropicalis 15378 R-XTR-548818 https://reactome.org/PathwayBrowser/#/R-XTR-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Xenopus tropicalis 15378 R-XTR-548831 https://reactome.org/PathwayBrowser/#/R-XTR-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Xenopus tropicalis 15378 R-XTR-5602295 https://reactome.org/PathwayBrowser/#/R-XTR-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Xenopus tropicalis 15378 R-XTR-5615668 https://reactome.org/PathwayBrowser/#/R-XTR-5615668 AKR1C3 reduces atRAL to atROL IEA Xenopus tropicalis 15378 R-XTR-5623643 https://reactome.org/PathwayBrowser/#/R-XTR-5623643 RDH13 reduces atRAL to atROL IEA Xenopus tropicalis 15378 R-XTR-5652172 https://reactome.org/PathwayBrowser/#/R-XTR-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Xenopus tropicalis 15378 R-XTR-5652195 https://reactome.org/PathwayBrowser/#/R-XTR-5652195 SORD oxidizes D-sorbitol to Fru IEA Xenopus tropicalis 15378 R-XTR-5661240 https://reactome.org/PathwayBrowser/#/R-XTR-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Xenopus tropicalis 15378 R-XTR-5661256 https://reactome.org/PathwayBrowser/#/R-XTR-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Xenopus tropicalis 15378 R-XTR-5661290 https://reactome.org/PathwayBrowser/#/R-XTR-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Xenopus tropicalis 15378 R-XTR-5662471 https://reactome.org/PathwayBrowser/#/R-XTR-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Xenopus tropicalis 15378 R-XTR-5662662 https://reactome.org/PathwayBrowser/#/R-XTR-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Xenopus tropicalis 15378 R-XTR-5668629 https://reactome.org/PathwayBrowser/#/R-XTR-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Xenopus tropicalis 15378 R-XTR-5668718 https://reactome.org/PathwayBrowser/#/R-XTR-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 15378 R-XTR-5668731 https://reactome.org/PathwayBrowser/#/R-XTR-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 15378 R-XTR-5690565 https://reactome.org/PathwayBrowser/#/R-XTR-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Xenopus tropicalis 15378 R-XTR-5691107 https://reactome.org/PathwayBrowser/#/R-XTR-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Xenopus tropicalis 15378 R-XTR-5692237 https://reactome.org/PathwayBrowser/#/R-XTR-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Xenopus tropicalis 15378 R-XTR-5693347 https://reactome.org/PathwayBrowser/#/R-XTR-5693347 CRYM reduces P2C to PPCA IEA Xenopus tropicalis 15378 R-XTR-5693390 https://reactome.org/PathwayBrowser/#/R-XTR-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Xenopus tropicalis 15378 R-XTR-5693681 https://reactome.org/PathwayBrowser/#/R-XTR-5693681 DUOX1,2 reduce O2 to H2O2 IEA Xenopus tropicalis 15378 R-XTR-5693691 https://reactome.org/PathwayBrowser/#/R-XTR-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Xenopus tropicalis 15378 R-XTR-5693761 https://reactome.org/PathwayBrowser/#/R-XTR-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Xenopus tropicalis 15378 R-XTR-5694018 https://reactome.org/PathwayBrowser/#/R-XTR-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Xenopus tropicalis 15378 R-XTR-5694462 https://reactome.org/PathwayBrowser/#/R-XTR-5694462 ABHD6,12 hydrolyse 3AG IEA Xenopus tropicalis 15378 R-XTR-5696080 https://reactome.org/PathwayBrowser/#/R-XTR-5696080 ALDH3B1 oxidises HXAL to PALM IEA Xenopus tropicalis 15378 R-XTR-5696091 https://reactome.org/PathwayBrowser/#/R-XTR-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Xenopus tropicalis 15378 R-XTR-5696101 https://reactome.org/PathwayBrowser/#/R-XTR-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Xenopus tropicalis 15378 R-XTR-5696131 https://reactome.org/PathwayBrowser/#/R-XTR-5696131 AOC1 deaminates Hist IEA Xenopus tropicalis 15378 R-XTR-5696183 https://reactome.org/PathwayBrowser/#/R-XTR-5696183 AOC3 deaminates BZAM IEA Xenopus tropicalis 15378 R-XTR-5696822 https://reactome.org/PathwayBrowser/#/R-XTR-5696822 AKR1B15 reduces EST17b to E1 IEA Xenopus tropicalis 15378 R-XTR-5696838 https://reactome.org/PathwayBrowser/#/R-XTR-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Xenopus tropicalis 15378 R-XTR-597628 https://reactome.org/PathwayBrowser/#/R-XTR-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Xenopus tropicalis 15378 R-XTR-6783221 https://reactome.org/PathwayBrowser/#/R-XTR-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Xenopus tropicalis 15378 R-XTR-6783939 https://reactome.org/PathwayBrowser/#/R-XTR-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 15378 R-XTR-6784399 https://reactome.org/PathwayBrowser/#/R-XTR-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Xenopus tropicalis 15378 R-XTR-6786239 https://reactome.org/PathwayBrowser/#/R-XTR-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Xenopus tropicalis 15378 R-XTR-6787642 https://reactome.org/PathwayBrowser/#/R-XTR-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Xenopus tropicalis 15378 R-XTR-6788999 https://reactome.org/PathwayBrowser/#/R-XTR-6788999 HV1-mediated H+ transfer IEA Xenopus tropicalis 15378 R-XTR-6789092 https://reactome.org/PathwayBrowser/#/R-XTR-6789092 NOX2 generates superoxide anion from oxygen IEA Xenopus tropicalis 15378 R-XTR-6793590 https://reactome.org/PathwayBrowser/#/R-XTR-6793590 LIPT2 transfers octanoyl group to GCSH IEA Xenopus tropicalis 15378 R-XTR-6799722 https://reactome.org/PathwayBrowser/#/R-XTR-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Xenopus tropicalis 15378 R-XTR-6801342 https://reactome.org/PathwayBrowser/#/R-XTR-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Xenopus tropicalis 15378 R-XTR-6806647 https://reactome.org/PathwayBrowser/#/R-XTR-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 15378 R-XTR-6806831 https://reactome.org/PathwayBrowser/#/R-XTR-6806831 CYB5Rs reduce MetHb to HbA IEA Xenopus tropicalis 15378 R-XTR-6806967 https://reactome.org/PathwayBrowser/#/R-XTR-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Xenopus tropicalis 15378 R-XTR-6807053 https://reactome.org/PathwayBrowser/#/R-XTR-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Xenopus tropicalis 15378 R-XTR-6807055 https://reactome.org/PathwayBrowser/#/R-XTR-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Xenopus tropicalis 15378 R-XTR-6807064 https://reactome.org/PathwayBrowser/#/R-XTR-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Xenopus tropicalis 15378 R-XTR-6807826 https://reactome.org/PathwayBrowser/#/R-XTR-6807826 LDHAL6B reduces PYR to LACT IEA Xenopus tropicalis 15378 R-XTR-6808464 https://reactome.org/PathwayBrowser/#/R-XTR-6808464 ALDH3B2 oxidises HXAL to PALM IEA Xenopus tropicalis 15378 R-XTR-6808487 https://reactome.org/PathwayBrowser/#/R-XTR-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 15378 R-XTR-6808496 https://reactome.org/PathwayBrowser/#/R-XTR-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 15378 R-XTR-6809264 https://reactome.org/PathwayBrowser/#/R-XTR-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Xenopus tropicalis 15378 R-XTR-6809287 https://reactome.org/PathwayBrowser/#/R-XTR-6809287 NUDT12 hydrolyses NADH to NMNH IEA Xenopus tropicalis 15378 R-XTR-6810594 https://reactome.org/PathwayBrowser/#/R-XTR-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 15378 R-XTR-6813749 https://reactome.org/PathwayBrowser/#/R-XTR-6813749 ALDH1A1 oxidises GA to DGA IEA Xenopus tropicalis 15378 R-XTR-6814153 https://reactome.org/PathwayBrowser/#/R-XTR-6814153 ADO oxidises 2AET to HTAU IEA Xenopus tropicalis 15378 R-XTR-70377 https://reactome.org/PathwayBrowser/#/R-XTR-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Xenopus tropicalis 15378 R-XTR-70420 https://reactome.org/PathwayBrowser/#/R-XTR-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Xenopus tropicalis 15378 R-XTR-70449 https://reactome.org/PathwayBrowser/#/R-XTR-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Xenopus tropicalis 15378 R-XTR-70482 https://reactome.org/PathwayBrowser/#/R-XTR-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Xenopus tropicalis 15378 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 15378 R-XTR-70510 https://reactome.org/PathwayBrowser/#/R-XTR-70510 LDH tetramer oxidises LACT to PYR IEA Xenopus tropicalis 15378 R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Xenopus tropicalis 15378 R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Xenopus tropicalis 15378 R-XTR-70664 https://reactome.org/PathwayBrowser/#/R-XTR-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 15378 R-XTR-70670 https://reactome.org/PathwayBrowser/#/R-XTR-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Xenopus tropicalis 15378 R-XTR-70679 https://reactome.org/PathwayBrowser/#/R-XTR-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Xenopus tropicalis 15378 R-XTR-70837 https://reactome.org/PathwayBrowser/#/R-XTR-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Xenopus tropicalis 15378 R-XTR-70885 https://reactome.org/PathwayBrowser/#/R-XTR-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Xenopus tropicalis 15378 R-XTR-70893 https://reactome.org/PathwayBrowser/#/R-XTR-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 15378 R-XTR-70906 https://reactome.org/PathwayBrowser/#/R-XTR-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Xenopus tropicalis 15378 R-XTR-70938 https://reactome.org/PathwayBrowser/#/R-XTR-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Xenopus tropicalis 15378 R-XTR-70940 https://reactome.org/PathwayBrowser/#/R-XTR-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Xenopus tropicalis 15378 R-XTR-70941 https://reactome.org/PathwayBrowser/#/R-XTR-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Xenopus tropicalis 15378 R-XTR-70975 https://reactome.org/PathwayBrowser/#/R-XTR-70975 CS acetylates OA to citrate IEA Xenopus tropicalis 15378 R-XTR-70979 https://reactome.org/PathwayBrowser/#/R-XTR-70979 MDH2 dimer dehydrogenates MAL IEA Xenopus tropicalis 15378 R-XTR-71130 https://reactome.org/PathwayBrowser/#/R-XTR-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Xenopus tropicalis 15378 R-XTR-71181 https://reactome.org/PathwayBrowser/#/R-XTR-71181 FAH cleaves 4FAA IEA Xenopus tropicalis 15378 R-XTR-71200 https://reactome.org/PathwayBrowser/#/R-XTR-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Xenopus tropicalis 15378 R-XTR-71260 https://reactome.org/PathwayBrowser/#/R-XTR-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Xenopus tropicalis 15378 R-XTR-71286 https://reactome.org/PathwayBrowser/#/R-XTR-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Xenopus tropicalis 15378 R-XTR-71401 https://reactome.org/PathwayBrowser/#/R-XTR-71401 OGDH dimer decarboxylates 2-OG IEA Xenopus tropicalis 15378 R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 15378 R-XTR-71682 https://reactome.org/PathwayBrowser/#/R-XTR-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 15378 R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 15378 R-XTR-71707 https://reactome.org/PathwayBrowser/#/R-XTR-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Xenopus tropicalis 15378 R-XTR-71723 https://reactome.org/PathwayBrowser/#/R-XTR-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Xenopus tropicalis 15378 R-XTR-71849 https://reactome.org/PathwayBrowser/#/R-XTR-71849 LDH tetramer reduces PYR to LACT IEA Xenopus tropicalis 15378 R-XTR-73564 https://reactome.org/PathwayBrowser/#/R-XTR-73564 UMPS dimer decarboxylates OMP to UMP IEA Xenopus tropicalis 15378 R-XTR-73571 https://reactome.org/PathwayBrowser/#/R-XTR-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Xenopus tropicalis 15378 R-XTR-73573 https://reactome.org/PathwayBrowser/#/R-XTR-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Xenopus tropicalis 15378 R-XTR-73577 https://reactome.org/PathwayBrowser/#/R-XTR-73577 CAD hexamer transforms L-Gln to CAP IEA Xenopus tropicalis 15378 R-XTR-73585 https://reactome.org/PathwayBrowser/#/R-XTR-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Xenopus tropicalis 15378 R-XTR-73596 https://reactome.org/PathwayBrowser/#/R-XTR-73596 dCMP + H2O => dUMP + NH4+ IEA Xenopus tropicalis 15378 R-XTR-73616 https://reactome.org/PathwayBrowser/#/R-XTR-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Xenopus tropicalis 15378 R-XTR-73666 https://reactome.org/PathwayBrowser/#/R-XTR-73666 dUTP + H2O => dUMP + pyrophosphate IEA Xenopus tropicalis 15378 R-XTR-73792 https://reactome.org/PathwayBrowser/#/R-XTR-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Xenopus tropicalis 15378 R-XTR-73794 https://reactome.org/PathwayBrowser/#/R-XTR-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Xenopus tropicalis 15378 R-XTR-73805 https://reactome.org/PathwayBrowser/#/R-XTR-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Xenopus tropicalis 15378 R-XTR-73806 https://reactome.org/PathwayBrowser/#/R-XTR-73806 AIR + CO2 => CAIR IEA Xenopus tropicalis 15378 R-XTR-73810 https://reactome.org/PathwayBrowser/#/R-XTR-73810 FGAM + ATP => AIR + ADP + Pi IEA Xenopus tropicalis 15378 R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 15378 R-XTR-73813 https://reactome.org/PathwayBrowser/#/R-XTR-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Xenopus tropicalis 15378 R-XTR-73814 https://reactome.org/PathwayBrowser/#/R-XTR-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Xenopus tropicalis 15378 R-XTR-73912 https://reactome.org/PathwayBrowser/#/R-XTR-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Xenopus tropicalis 15378 R-XTR-73920 https://reactome.org/PathwayBrowser/#/R-XTR-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Xenopus tropicalis 15378 R-XTR-74255 https://reactome.org/PathwayBrowser/#/R-XTR-74255 Guanine + H2O => Xanthine + NH4+ IEA Xenopus tropicalis 15378 R-XTR-74723 https://reactome.org/PathwayBrowser/#/R-XTR-74723 Endosome acidification IEA Xenopus tropicalis 15378 R-XTR-74872 https://reactome.org/PathwayBrowser/#/R-XTR-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 15378 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 15378 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15378 R-XTR-75872 https://reactome.org/PathwayBrowser/#/R-XTR-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Xenopus tropicalis 15378 R-XTR-75883 https://reactome.org/PathwayBrowser/#/R-XTR-75883 DHRS7B reduces GO3P to HXDG3P IEA Xenopus tropicalis 15378 R-XTR-75889 https://reactome.org/PathwayBrowser/#/R-XTR-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Xenopus tropicalis 15378 R-XTR-76354 https://reactome.org/PathwayBrowser/#/R-XTR-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Xenopus tropicalis 15378 R-XTR-76416 https://reactome.org/PathwayBrowser/#/R-XTR-76416 Benzene is hydroxylated to phenol IEA Xenopus tropicalis 15378 R-XTR-76453 https://reactome.org/PathwayBrowser/#/R-XTR-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Xenopus tropicalis 15378 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 15378 R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 15378 R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 15378 R-XTR-77254 https://reactome.org/PathwayBrowser/#/R-XTR-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-XTR-77283 https://reactome.org/PathwayBrowser/#/R-XTR-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-XTR-77303 https://reactome.org/PathwayBrowser/#/R-XTR-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-XTR-77312 https://reactome.org/PathwayBrowser/#/R-XTR-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-XTR-77323 https://reactome.org/PathwayBrowser/#/R-XTR-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-XTR-77331 https://reactome.org/PathwayBrowser/#/R-XTR-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-XTR-77342 https://reactome.org/PathwayBrowser/#/R-XTR-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-XTR-804969 https://reactome.org/PathwayBrowser/#/R-XTR-804969 HSD17B1 hydrogenates E1 to EST17b IEA Xenopus tropicalis 15378 R-XTR-8850846 https://reactome.org/PathwayBrowser/#/R-XTR-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-XTR-8850854 https://reactome.org/PathwayBrowser/#/R-XTR-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15378 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-XTR-8851110 https://reactome.org/PathwayBrowser/#/R-XTR-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-XTR-8851129 https://reactome.org/PathwayBrowser/#/R-XTR-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15378 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15378 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15378 R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15378 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 15378 R-XTR-8862137 https://reactome.org/PathwayBrowser/#/R-XTR-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 15378 R-XTR-8862152 https://reactome.org/PathwayBrowser/#/R-XTR-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Xenopus tropicalis 15378 R-XTR-8863494 https://reactome.org/PathwayBrowser/#/R-XTR-8863494 ASICs bind STOML3, (STOM) IEA Xenopus tropicalis 15378 R-XTR-8866601 https://reactome.org/PathwayBrowser/#/R-XTR-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Xenopus tropicalis 15378 R-XTR-8870346 https://reactome.org/PathwayBrowser/#/R-XTR-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Xenopus tropicalis 15378 R-XTR-8875623 https://reactome.org/PathwayBrowser/#/R-XTR-8875623 SLC25A18,22 import L-Glu, H+ IEA Xenopus tropicalis 15378 R-XTR-888548 https://reactome.org/PathwayBrowser/#/R-XTR-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Xenopus tropicalis 15378 R-XTR-888572 https://reactome.org/PathwayBrowser/#/R-XTR-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Xenopus tropicalis 15378 R-XTR-888577 https://reactome.org/PathwayBrowser/#/R-XTR-888577 Synthesis of GABA by GAD2 IEA Xenopus tropicalis 15378 R-XTR-8936442 https://reactome.org/PathwayBrowser/#/R-XTR-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Xenopus tropicalis 15378 R-XTR-8938076 https://reactome.org/PathwayBrowser/#/R-XTR-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Xenopus tropicalis 15378 R-XTR-8952873 https://reactome.org/PathwayBrowser/#/R-XTR-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Xenopus tropicalis 15378 R-XTR-8954468 https://reactome.org/PathwayBrowser/#/R-XTR-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Xenopus tropicalis 15378 R-XTR-8955030 https://reactome.org/PathwayBrowser/#/R-XTR-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 15378 R-XTR-8955760 https://reactome.org/PathwayBrowser/#/R-XTR-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Xenopus tropicalis 15378 R-XTR-8956458 https://reactome.org/PathwayBrowser/#/R-XTR-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Xenopus tropicalis 15378 R-XTR-8959719 https://reactome.org/PathwayBrowser/#/R-XTR-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Xenopus tropicalis 15378 R-XTR-9011595 https://reactome.org/PathwayBrowser/#/R-XTR-9011595 GSTZ1 dimer dehalogenates DCA IEA Xenopus tropicalis 15378 R-XTR-9012016 https://reactome.org/PathwayBrowser/#/R-XTR-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Xenopus tropicalis 15378 R-XTR-9024993 https://reactome.org/PathwayBrowser/#/R-XTR-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Xenopus tropicalis 15378 R-XTR-9027043 https://reactome.org/PathwayBrowser/#/R-XTR-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Xenopus tropicalis 15378 R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 15378 R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 15378 R-XTR-917811 https://reactome.org/PathwayBrowser/#/R-XTR-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Xenopus tropicalis 15378 R-XTR-917841 https://reactome.org/PathwayBrowser/#/R-XTR-917841 Acidification of Tf:TfR1 containing endosome IEA Xenopus tropicalis 15378 R-XTR-917891 https://reactome.org/PathwayBrowser/#/R-XTR-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Xenopus tropicalis 15378 R-XTR-917933 https://reactome.org/PathwayBrowser/#/R-XTR-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Xenopus tropicalis 15378 R-XTR-917979 https://reactome.org/PathwayBrowser/#/R-XTR-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Xenopus tropicalis 15378 R-XTR-937311 https://reactome.org/PathwayBrowser/#/R-XTR-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 15378 R-XTR-9620103 https://reactome.org/PathwayBrowser/#/R-XTR-9620103 ALDH2 transforms GTN to NO IEA Xenopus tropicalis 15378 R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-XTR-9650165 https://reactome.org/PathwayBrowser/#/R-XTR-9650165 ASIC trimers bind H+ IEA Xenopus tropicalis 15378 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 15378 R-XTR-9705713 https://reactome.org/PathwayBrowser/#/R-XTR-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 15378 R-XTR-9705714 https://reactome.org/PathwayBrowser/#/R-XTR-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 15378 R-XTR-9727198 https://reactome.org/PathwayBrowser/#/R-XTR-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 15378 R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 15378 R-XTR-9727349 https://reactome.org/PathwayBrowser/#/R-XTR-9727349 XDH dehydrogenates xanthine to form urate IEA Xenopus tropicalis 15378 R-XTR-9731228 https://reactome.org/PathwayBrowser/#/R-XTR-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Xenopus tropicalis 15378 R-XTR-9731590 https://reactome.org/PathwayBrowser/#/R-XTR-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Xenopus tropicalis 15378 R-XTR-9731613 https://reactome.org/PathwayBrowser/#/R-XTR-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Xenopus tropicalis 15378 R-XTR-9731632 https://reactome.org/PathwayBrowser/#/R-XTR-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Xenopus tropicalis 15378 R-XTR-9731661 https://reactome.org/PathwayBrowser/#/R-XTR-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Xenopus tropicalis 15378 R-XTR-9748945 https://reactome.org/PathwayBrowser/#/R-XTR-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Xenopus tropicalis 15378 R-XTR-9748957 https://reactome.org/PathwayBrowser/#/R-XTR-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Xenopus tropicalis 15378 R-XTR-9748979 https://reactome.org/PathwayBrowser/#/R-XTR-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Xenopus tropicalis 15378 R-XTR-9748983 https://reactome.org/PathwayBrowser/#/R-XTR-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Xenopus tropicalis 15378 R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 15378 R-XTR-9749609 https://reactome.org/PathwayBrowser/#/R-XTR-9749609 BCHE hydrolyzes ASA- IEA Xenopus tropicalis 15378 R-XTR-9749792 https://reactome.org/PathwayBrowser/#/R-XTR-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Xenopus tropicalis 15378 R-XTR-9753285 https://reactome.org/PathwayBrowser/#/R-XTR-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Xenopus tropicalis 15378 R-XTR-9755937 https://reactome.org/PathwayBrowser/#/R-XTR-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Xenopus tropicalis 15378 R-XTR-9756138 https://reactome.org/PathwayBrowser/#/R-XTR-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Xenopus tropicalis 15378 R-XTR-9756162 https://reactome.org/PathwayBrowser/#/R-XTR-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Xenopus tropicalis 15378 R-XTR-9756169 https://reactome.org/PathwayBrowser/#/R-XTR-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Xenopus tropicalis 15378 R-XTR-9756177 https://reactome.org/PathwayBrowser/#/R-XTR-9756177 PON1,3 hydrolyse ATVL to ATV IEA Xenopus tropicalis 15378 R-XTR-9756180 https://reactome.org/PathwayBrowser/#/R-XTR-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Xenopus tropicalis 15378 R-XTR-9757706 https://reactome.org/PathwayBrowser/#/R-XTR-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Xenopus tropicalis 15378 R-XTR-9758674 https://reactome.org/PathwayBrowser/#/R-XTR-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Xenopus tropicalis 15378 R-XTR-9758682 https://reactome.org/PathwayBrowser/#/R-XTR-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Xenopus tropicalis 15378 R-XTR-9759259 https://reactome.org/PathwayBrowser/#/R-XTR-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Xenopus tropicalis 15378 R-XTR-9759549 https://reactome.org/PathwayBrowser/#/R-XTR-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Xenopus tropicalis 15378 R-XTR-977348 https://reactome.org/PathwayBrowser/#/R-XTR-977348 PHGDH tetramer dehydrogenates 3PG IEA Xenopus tropicalis 15378 R-XTR-9837337 https://reactome.org/PathwayBrowser/#/R-XTR-9837337 DCAKD phosphorylates DP-CoA IEA Xenopus tropicalis 15378 R-XTR-9843721 https://reactome.org/PathwayBrowser/#/R-XTR-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Xenopus tropicalis 15378 R-XTR-9844587 https://reactome.org/PathwayBrowser/#/R-XTR-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Xenopus tropicalis 15378 R-XTR-9845516 https://reactome.org/PathwayBrowser/#/R-XTR-9845516 B3GALT4 transfers Gal to gangliosides IEA Xenopus tropicalis 15378 R-XTR-9845538 https://reactome.org/PathwayBrowser/#/R-XTR-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Xenopus tropicalis 15378 R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 15378 R-XTR-9846305 https://reactome.org/PathwayBrowser/#/R-XTR-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Xenopus tropicalis 15378 R-XTR-9846332 https://reactome.org/PathwayBrowser/#/R-XTR-9846332 FUT1,2 transfer fucose to gangliosides IEA Xenopus tropicalis 15378 R-XTR-9846501 https://reactome.org/PathwayBrowser/#/R-XTR-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Xenopus tropicalis 15378 R-XTR-9851347 https://reactome.org/PathwayBrowser/#/R-XTR-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Xenopus tropicalis 15378 R-XTR-9853499 https://reactome.org/PathwayBrowser/#/R-XTR-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 15378 R-XTR-9854415 https://reactome.org/PathwayBrowser/#/R-XTR-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Xenopus tropicalis 15378 R-XTR-9856871 https://reactome.org/PathwayBrowser/#/R-XTR-9856871 MDH1 reduces OA IEA Xenopus tropicalis 15378 R-XTR-9861616 https://reactome.org/PathwayBrowser/#/R-XTR-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 15378 R-XTR-9861734 https://reactome.org/PathwayBrowser/#/R-XTR-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Xenopus tropicalis 15379 R-BTA-1222376 https://reactome.org/PathwayBrowser/#/R-BTA-1222376 NOX2 generates superoxide from oxygen IEA Bos taurus 15379 R-BTA-1234164 https://reactome.org/PathwayBrowser/#/R-BTA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Bos taurus 15379 R-BTA-1234165 https://reactome.org/PathwayBrowser/#/R-BTA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Bos taurus 15379 R-BTA-1234173 https://reactome.org/PathwayBrowser/#/R-BTA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Bos taurus 15379 R-BTA-1234177 https://reactome.org/PathwayBrowser/#/R-BTA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Bos taurus 15379 R-BTA-1234181 https://reactome.org/PathwayBrowser/#/R-BTA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Bos taurus 15379 R-BTA-1236967 https://reactome.org/PathwayBrowser/#/R-BTA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Bos taurus 15379 R-BTA-1237119 https://reactome.org/PathwayBrowser/#/R-BTA-1237119 Acireductone is oxidized to MOB IEA Bos taurus 15379 R-BTA-1237325 https://reactome.org/PathwayBrowser/#/R-BTA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Bos taurus 15379 R-BTA-1247668 https://reactome.org/PathwayBrowser/#/R-BTA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Bos taurus 15379 R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 15379 R-BTA-140355 https://reactome.org/PathwayBrowser/#/R-BTA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Bos taurus 15379 R-BTA-141186 https://reactome.org/PathwayBrowser/#/R-BTA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Bos taurus 15379 R-BTA-141200 https://reactome.org/PathwayBrowser/#/R-BTA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Bos taurus 15379 R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus 15379 R-BTA-141341 https://reactome.org/PathwayBrowser/#/R-BTA-141341 SMOX-3 oxidises SPN to SPM IEA Bos taurus 15379 R-BTA-141348 https://reactome.org/PathwayBrowser/#/R-BTA-141348 PAO:FAD oxidises NASPM to PTCN IEA Bos taurus 15379 R-BTA-141351 https://reactome.org/PathwayBrowser/#/R-BTA-141351 PAOX:FAD oxidises NASPN to SPM IEA Bos taurus 15379 R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 15379 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 15379 R-BTA-1562626 https://reactome.org/PathwayBrowser/#/R-BTA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Bos taurus 15379 R-BTA-156526 https://reactome.org/PathwayBrowser/#/R-BTA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Bos taurus 15379 R-BTA-159752 https://reactome.org/PathwayBrowser/#/R-BTA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Bos taurus 15379 R-BTA-159761 https://reactome.org/PathwayBrowser/#/R-BTA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Bos taurus 15379 R-BTA-159795 https://reactome.org/PathwayBrowser/#/R-BTA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Bos taurus 15379 R-BTA-159803 https://reactome.org/PathwayBrowser/#/R-BTA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Bos taurus 15379 R-BTA-159819 https://reactome.org/PathwayBrowser/#/R-BTA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Bos taurus 15379 R-BTA-159826 https://reactome.org/PathwayBrowser/#/R-BTA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Bos taurus 15379 R-BTA-1614544 https://reactome.org/PathwayBrowser/#/R-BTA-1614544 Sulfite is oxidized to sulfate IEA Bos taurus 15379 R-BTA-1614605 https://reactome.org/PathwayBrowser/#/R-BTA-1614605 Persulfide sulfur is dioxygenated IEA Bos taurus 15379 R-BTA-1614645 https://reactome.org/PathwayBrowser/#/R-BTA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Bos taurus 15379 R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 15379 R-BTA-163820 https://reactome.org/PathwayBrowser/#/R-BTA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Bos taurus 15379 R-BTA-1650808 https://reactome.org/PathwayBrowser/#/R-BTA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Bos taurus 15379 R-BTA-1655453 https://reactome.org/PathwayBrowser/#/R-BTA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Bos taurus 15379 R-BTA-189398 https://reactome.org/PathwayBrowser/#/R-BTA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Bos taurus 15379 R-BTA-189421 https://reactome.org/PathwayBrowser/#/R-BTA-189421 CPO transforms COPRO3 to PPGEN9 IEA Bos taurus 15379 R-BTA-189423 https://reactome.org/PathwayBrowser/#/R-BTA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Bos taurus 15379 R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 15379 R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 15379 R-BTA-191999 https://reactome.org/PathwayBrowser/#/R-BTA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Bos taurus 15379 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 15379 R-BTA-192054 https://reactome.org/PathwayBrowser/#/R-BTA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Bos taurus 15379 R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 15379 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 15379 R-BTA-192123 https://reactome.org/PathwayBrowser/#/R-BTA-192123 CYP27A1 27-hydroxylates CHOL IEA Bos taurus 15379 R-BTA-192178 https://reactome.org/PathwayBrowser/#/R-BTA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Bos taurus 15379 R-BTA-192335 https://reactome.org/PathwayBrowser/#/R-BTA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Bos taurus 15379 R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 15379 R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 15379 R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 15379 R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 15379 R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 15379 R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 15379 R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 15379 R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 15379 R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 15379 R-BTA-193369 https://reactome.org/PathwayBrowser/#/R-BTA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Bos taurus 15379 R-BTA-193393 https://reactome.org/PathwayBrowser/#/R-BTA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Bos taurus 15379 R-BTA-193460 https://reactome.org/PathwayBrowser/#/R-BTA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Bos taurus 15379 R-BTA-193713 https://reactome.org/PathwayBrowser/#/R-BTA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Bos taurus 15379 R-BTA-193719 https://reactome.org/PathwayBrowser/#/R-BTA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 15379 R-BTA-193737 https://reactome.org/PathwayBrowser/#/R-BTA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Bos taurus 15379 R-BTA-193780 https://reactome.org/PathwayBrowser/#/R-BTA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Bos taurus 15379 R-BTA-193787 https://reactome.org/PathwayBrowser/#/R-BTA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Bos taurus 15379 R-BTA-193792 https://reactome.org/PathwayBrowser/#/R-BTA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Bos taurus 15379 R-BTA-193964 https://reactome.org/PathwayBrowser/#/R-BTA-193964 CYP21A2 21-hydroxylates PROG IEA Bos taurus 15379 R-BTA-193965 https://reactome.org/PathwayBrowser/#/R-BTA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Bos taurus 15379 R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 15379 R-BTA-193995 https://reactome.org/PathwayBrowser/#/R-BTA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Bos taurus 15379 R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 15379 R-BTA-194017 https://reactome.org/PathwayBrowser/#/R-BTA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Bos taurus 15379 R-BTA-194641 https://reactome.org/PathwayBrowser/#/R-BTA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15379 R-BTA-194669 https://reactome.org/PathwayBrowser/#/R-BTA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15379 R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 15379 R-BTA-195664 https://reactome.org/PathwayBrowser/#/R-BTA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Bos taurus 15379 R-BTA-1980233 https://reactome.org/PathwayBrowser/#/R-BTA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Bos taurus 15379 R-BTA-1981104 https://reactome.org/PathwayBrowser/#/R-BTA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Bos taurus 15379 R-BTA-198563 https://reactome.org/PathwayBrowser/#/R-BTA-198563 IDO1 dioxygenates L-Trp to NFK IEA Bos taurus 15379 R-BTA-2002466 https://reactome.org/PathwayBrowser/#/R-BTA-2002466 Formation of allysine by LOX IEA Bos taurus 15379 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 15379 R-BTA-2046084 https://reactome.org/PathwayBrowser/#/R-BTA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Bos taurus 15379 R-BTA-2046089 https://reactome.org/PathwayBrowser/#/R-BTA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Bos taurus 15379 R-BTA-2046092 https://reactome.org/PathwayBrowser/#/R-BTA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Bos taurus 15379 R-BTA-2046096 https://reactome.org/PathwayBrowser/#/R-BTA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Bos taurus 15379 R-BTA-2046097 https://reactome.org/PathwayBrowser/#/R-BTA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 15379 R-BTA-204662 https://reactome.org/PathwayBrowser/#/R-BTA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Bos taurus 15379 R-BTA-2066787 https://reactome.org/PathwayBrowser/#/R-BTA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Bos taurus 15379 R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 15379 R-BTA-209823 https://reactome.org/PathwayBrowser/#/R-BTA-209823 Tyrosine is hydroxylated to dopa IEA Bos taurus 15379 R-BTA-209828 https://reactome.org/PathwayBrowser/#/R-BTA-209828 Tryptophan is hydroxylated IEA Bos taurus 15379 R-BTA-209845 https://reactome.org/PathwayBrowser/#/R-BTA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Bos taurus 15379 R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 15379 R-BTA-209891 https://reactome.org/PathwayBrowser/#/R-BTA-209891 Dopamine is oxidised to noradrenaline IEA Bos taurus 15379 R-BTA-211873 https://reactome.org/PathwayBrowser/#/R-BTA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Bos taurus 15379 R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 15379 R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 15379 R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 15379 R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 15379 R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 15379 R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 15379 R-BTA-211923 https://reactome.org/PathwayBrowser/#/R-BTA-211923 CYP26C1 4-hydroxylates 9cRA IEA Bos taurus 15379 R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 15379 R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 15379 R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 15379 R-BTA-211950 https://reactome.org/PathwayBrowser/#/R-BTA-211950 CYP24A1 24-hydroxylates CTL IEA Bos taurus 15379 R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 15379 R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 15379 R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 15379 R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 15379 R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 15379 R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 15379 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 15379 R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 15379 R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 15379 R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 15379 R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 15379 R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 15379 R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 15379 R-BTA-2160492 https://reactome.org/PathwayBrowser/#/R-BTA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Bos taurus 15379 R-BTA-2161745 https://reactome.org/PathwayBrowser/#/R-BTA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Bos taurus 15379 R-BTA-2161775 https://reactome.org/PathwayBrowser/#/R-BTA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Bos taurus 15379 R-BTA-2161792 https://reactome.org/PathwayBrowser/#/R-BTA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Bos taurus 15379 R-BTA-2161794 https://reactome.org/PathwayBrowser/#/R-BTA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Bos taurus 15379 R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Bos taurus 15379 R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 15379 R-BTA-2161890 https://reactome.org/PathwayBrowser/#/R-BTA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Bos taurus 15379 R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Bos taurus 15379 R-BTA-2161907 https://reactome.org/PathwayBrowser/#/R-BTA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Bos taurus 15379 R-BTA-2161917 https://reactome.org/PathwayBrowser/#/R-BTA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Bos taurus 15379 R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 15379 R-BTA-2161950 https://reactome.org/PathwayBrowser/#/R-BTA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Bos taurus 15379 R-BTA-2161951 https://reactome.org/PathwayBrowser/#/R-BTA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Bos taurus 15379 R-BTA-2161964 https://reactome.org/PathwayBrowser/#/R-BTA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Bos taurus 15379 R-BTA-2162002 https://reactome.org/PathwayBrowser/#/R-BTA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Bos taurus 15379 R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 15379 R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 15379 R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 15379 R-BTA-2172678 https://reactome.org/PathwayBrowser/#/R-BTA-2172678 PHF8 demethylates histone H4K20me1 IEA Bos taurus 15379 R-BTA-2230938 https://reactome.org/PathwayBrowser/#/R-BTA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Bos taurus 15379 R-BTA-2309787 https://reactome.org/PathwayBrowser/#/R-BTA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Bos taurus 15379 R-BTA-2395340 https://reactome.org/PathwayBrowser/#/R-BTA-2395340 Formation of hydroxyallysine by LOX IEA Bos taurus 15379 R-BTA-265296 https://reactome.org/PathwayBrowser/#/R-BTA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Bos taurus 15379 R-BTA-3204311 https://reactome.org/PathwayBrowser/#/R-BTA-3204311 AOX1 oxidises PXL to PDXate IEA Bos taurus 15379 R-BTA-3299680 https://reactome.org/PathwayBrowser/#/R-BTA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Bos taurus 15379 R-BTA-3299682 https://reactome.org/PathwayBrowser/#/R-BTA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Bos taurus 15379 R-BTA-3299691 https://reactome.org/PathwayBrowser/#/R-BTA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Bos taurus 15379 R-BTA-3341294 https://reactome.org/PathwayBrowser/#/R-BTA-3341294 Superoxide reduces cytochrome c IEA Bos taurus 15379 R-BTA-374909 https://reactome.org/PathwayBrowser/#/R-BTA-374909 Catabolism of Noradrenaline IEA Bos taurus 15379 R-BTA-3777112 https://reactome.org/PathwayBrowser/#/R-BTA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Bos taurus 15379 R-BTA-379382 https://reactome.org/PathwayBrowser/#/R-BTA-379382 MAOA:FAD deaminates DA to DOPAC IEA Bos taurus 15379 R-BTA-379395 https://reactome.org/PathwayBrowser/#/R-BTA-379395 MAOA:FAD deaminates 3MT to HVA IEA Bos taurus 15379 R-BTA-389639 https://reactome.org/PathwayBrowser/#/R-BTA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Bos taurus 15379 R-BTA-389821 https://reactome.org/PathwayBrowser/#/R-BTA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Bos taurus 15379 R-BTA-389842 https://reactome.org/PathwayBrowser/#/R-BTA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Bos taurus 15379 R-BTA-389862 https://reactome.org/PathwayBrowser/#/R-BTA-389862 Conversion of glyoxylate to oxalate IEA Bos taurus 15379 R-BTA-389889 https://reactome.org/PathwayBrowser/#/R-BTA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Bos taurus 15379 R-BTA-389891 https://reactome.org/PathwayBrowser/#/R-BTA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Bos taurus 15379 R-BTA-390256 https://reactome.org/PathwayBrowser/#/R-BTA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Bos taurus 15379 R-BTA-418436 https://reactome.org/PathwayBrowser/#/R-BTA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Bos taurus 15379 R-BTA-428259 https://reactome.org/PathwayBrowser/#/R-BTA-428259 DEGS1 dehydrogenates dihydroceramide IEA Bos taurus 15379 R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 15379 R-BTA-4722133 https://reactome.org/PathwayBrowser/#/R-BTA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Bos taurus 15379 R-BTA-4724279 https://reactome.org/PathwayBrowser/#/R-BTA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Bos taurus 15379 R-BTA-4724284 https://reactome.org/PathwayBrowser/#/R-BTA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Bos taurus 15379 R-BTA-4754176 https://reactome.org/PathwayBrowser/#/R-BTA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Bos taurus 15379 R-BTA-4754181 https://reactome.org/PathwayBrowser/#/R-BTA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Bos taurus 15379 R-BTA-4754187 https://reactome.org/PathwayBrowser/#/R-BTA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Bos taurus 15379 R-BTA-5164399 https://reactome.org/PathwayBrowser/#/R-BTA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Bos taurus 15379 R-BTA-5218841 https://reactome.org/PathwayBrowser/#/R-BTA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Bos taurus 15379 R-BTA-5340214 https://reactome.org/PathwayBrowser/#/R-BTA-5340214 CYGB binds O2 IEA Bos taurus 15379 R-BTA-5340226 https://reactome.org/PathwayBrowser/#/R-BTA-5340226 CYGB dioxygenates NO IEA Bos taurus 15379 R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 15379 R-BTA-5423117 https://reactome.org/PathwayBrowser/#/R-BTA-5423117 PHF8 demethylates MeK21-histone H4 IEA Bos taurus 15379 R-BTA-5423647 https://reactome.org/PathwayBrowser/#/R-BTA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Bos taurus 15379 R-BTA-5423664 https://reactome.org/PathwayBrowser/#/R-BTA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Bos taurus 15379 R-BTA-5423672 https://reactome.org/PathwayBrowser/#/R-BTA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Bos taurus 15379 R-BTA-5423678 https://reactome.org/PathwayBrowser/#/R-BTA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Bos taurus 15379 R-BTA-5602295 https://reactome.org/PathwayBrowser/#/R-BTA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Bos taurus 15379 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 15379 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 15379 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 15379 R-BTA-5661114 https://reactome.org/PathwayBrowser/#/R-BTA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Bos taurus 15379 R-BTA-5661115 https://reactome.org/PathwayBrowser/#/R-BTA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Bos taurus 15379 R-BTA-5661116 https://reactome.org/PathwayBrowser/#/R-BTA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Bos taurus 15379 R-BTA-5661120 https://reactome.org/PathwayBrowser/#/R-BTA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Bos taurus 15379 R-BTA-5661121 https://reactome.org/PathwayBrowser/#/R-BTA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Bos taurus 15379 R-BTA-5661122 https://reactome.org/PathwayBrowser/#/R-BTA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Bos taurus 15379 R-BTA-5661124 https://reactome.org/PathwayBrowser/#/R-BTA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Bos taurus 15379 R-BTA-5661125 https://reactome.org/PathwayBrowser/#/R-BTA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Bos taurus 15379 R-BTA-5662692 https://reactome.org/PathwayBrowser/#/R-BTA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Bos taurus 15379 R-BTA-5668629 https://reactome.org/PathwayBrowser/#/R-BTA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Bos taurus 15379 R-BTA-5668718 https://reactome.org/PathwayBrowser/#/R-BTA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 15379 R-BTA-5668731 https://reactome.org/PathwayBrowser/#/R-BTA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 15379 R-BTA-5678327 https://reactome.org/PathwayBrowser/#/R-BTA-5678327 MIOX oxidises Ins to GlcA IEA Bos taurus 15379 R-BTA-5690565 https://reactome.org/PathwayBrowser/#/R-BTA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Bos taurus 15379 R-BTA-5691107 https://reactome.org/PathwayBrowser/#/R-BTA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Bos taurus 15379 R-BTA-5693681 https://reactome.org/PathwayBrowser/#/R-BTA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Bos taurus 15379 R-BTA-5693761 https://reactome.org/PathwayBrowser/#/R-BTA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Bos taurus 15379 R-BTA-5696119 https://reactome.org/PathwayBrowser/#/R-BTA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Bos taurus 15379 R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 15379 R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 15379 R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 15379 R-BTA-6783880 https://reactome.org/PathwayBrowser/#/R-BTA-6783880 PIPOX oxidises PPCA to P6C IEA Bos taurus 15379 R-BTA-6786239 https://reactome.org/PathwayBrowser/#/R-BTA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Bos taurus 15379 R-BTA-6787811 https://reactome.org/PathwayBrowser/#/R-BTA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Bos taurus 15379 R-BTA-6789092 https://reactome.org/PathwayBrowser/#/R-BTA-6789092 NOX2 generates superoxide anion from oxygen IEA Bos taurus 15379 R-BTA-6807053 https://reactome.org/PathwayBrowser/#/R-BTA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Bos taurus 15379 R-BTA-6807214 https://reactome.org/PathwayBrowser/#/R-BTA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Bos taurus 15379 R-BTA-6807557 https://reactome.org/PathwayBrowser/#/R-BTA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Bos taurus 15379 R-BTA-6810076 https://reactome.org/PathwayBrowser/#/R-BTA-6810076 DDO oxidizes D-Asp to OA IEA Bos taurus 15379 R-BTA-6814153 https://reactome.org/PathwayBrowser/#/R-BTA-6814153 ADO oxidises 2AET to HTAU IEA Bos taurus 15379 R-BTA-71118 https://reactome.org/PathwayBrowser/#/R-BTA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Bos taurus 15379 R-BTA-71163 https://reactome.org/PathwayBrowser/#/R-BTA-71163 HPD dioxygenates HPP IEA Bos taurus 15379 R-BTA-71164 https://reactome.org/PathwayBrowser/#/R-BTA-71164 HGD dioxygenates homogentisate IEA Bos taurus 15379 R-BTA-71188 https://reactome.org/PathwayBrowser/#/R-BTA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Bos taurus 15379 R-BTA-71200 https://reactome.org/PathwayBrowser/#/R-BTA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Bos taurus 15379 R-BTA-71218 https://reactome.org/PathwayBrowser/#/R-BTA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Bos taurus 15379 R-BTA-71241 https://reactome.org/PathwayBrowser/#/R-BTA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Bos taurus 15379 R-BTA-71261 https://reactome.org/PathwayBrowser/#/R-BTA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Bos taurus 15379 R-BTA-74247 https://reactome.org/PathwayBrowser/#/R-BTA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Bos taurus 15379 R-BTA-74258 https://reactome.org/PathwayBrowser/#/R-BTA-74258 XDH oxidizes xanthine to form urate IEA Bos taurus 15379 R-BTA-76031 https://reactome.org/PathwayBrowser/#/R-BTA-76031 2 H2O2 => O2 + 2 H2O IEA Bos taurus 15379 R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 15379 R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 15379 R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 15379 R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 15379 R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 15379 R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 15379 R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 15379 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 15379 R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 15379 R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 15379 R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 15379 R-BTA-8847579 https://reactome.org/PathwayBrowser/#/R-BTA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Bos taurus 15379 R-BTA-8878581 https://reactome.org/PathwayBrowser/#/R-BTA-8878581 TYRP1 oxidises DHICA to IQCA IEA Bos taurus 15379 R-BTA-888614 https://reactome.org/PathwayBrowser/#/R-BTA-888614 IDO2 dioxygenates L-Trp to NFK IEA Bos taurus 15379 R-BTA-8953398 https://reactome.org/PathwayBrowser/#/R-BTA-8953398 PIR oxygenates quercetin IEA Bos taurus 15379 R-BTA-8956458 https://reactome.org/PathwayBrowser/#/R-BTA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Bos taurus 15379 R-BTA-8981606 https://reactome.org/PathwayBrowser/#/R-BTA-8981606 Myoglobin binds oxygen IEA Bos taurus 15379 R-BTA-8981610 https://reactome.org/PathwayBrowser/#/R-BTA-8981610 Neuroglobin binds oxygen IEA Bos taurus 15379 R-BTA-8981621 https://reactome.org/PathwayBrowser/#/R-BTA-8981621 Neuroglobin:oxygen dissociates IEA Bos taurus 15379 R-BTA-8981622 https://reactome.org/PathwayBrowser/#/R-BTA-8981622 Myoglobin:oxygen dissociates IEA Bos taurus 15379 R-BTA-8982617 https://reactome.org/PathwayBrowser/#/R-BTA-8982617 CYGB:O2 dissociates IEA Bos taurus 15379 R-BTA-9018858 https://reactome.org/PathwayBrowser/#/R-BTA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Bos taurus 15379 R-BTA-9018859 https://reactome.org/PathwayBrowser/#/R-BTA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Bos taurus 15379 R-BTA-9018863 https://reactome.org/PathwayBrowser/#/R-BTA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Bos taurus 15379 R-BTA-9018880 https://reactome.org/PathwayBrowser/#/R-BTA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Bos taurus 15379 R-BTA-9018894 https://reactome.org/PathwayBrowser/#/R-BTA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Bos taurus 15379 R-BTA-9018907 https://reactome.org/PathwayBrowser/#/R-BTA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Bos taurus 15379 R-BTA-9020251 https://reactome.org/PathwayBrowser/#/R-BTA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Bos taurus 15379 R-BTA-9020259 https://reactome.org/PathwayBrowser/#/R-BTA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Bos taurus 15379 R-BTA-9020261 https://reactome.org/PathwayBrowser/#/R-BTA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Bos taurus 15379 R-BTA-9020264 https://reactome.org/PathwayBrowser/#/R-BTA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Bos taurus 15379 R-BTA-9020274 https://reactome.org/PathwayBrowser/#/R-BTA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Bos taurus 15379 R-BTA-9020275 https://reactome.org/PathwayBrowser/#/R-BTA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Bos taurus 15379 R-BTA-9020282 https://reactome.org/PathwayBrowser/#/R-BTA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Bos taurus 15379 R-BTA-9020610 https://reactome.org/PathwayBrowser/#/R-BTA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Bos taurus 15379 R-BTA-9024872 https://reactome.org/PathwayBrowser/#/R-BTA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Bos taurus 15379 R-BTA-9024997 https://reactome.org/PathwayBrowser/#/R-BTA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Bos taurus 15379 R-BTA-9025152 https://reactome.org/PathwayBrowser/#/R-BTA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Bos taurus 15379 R-BTA-9025957 https://reactome.org/PathwayBrowser/#/R-BTA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Bos taurus 15379 R-BTA-9025996 https://reactome.org/PathwayBrowser/#/R-BTA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Bos taurus 15379 R-BTA-9026003 https://reactome.org/PathwayBrowser/#/R-BTA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Bos taurus 15379 R-BTA-9026005 https://reactome.org/PathwayBrowser/#/R-BTA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Bos taurus 15379 R-BTA-9026006 https://reactome.org/PathwayBrowser/#/R-BTA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Bos taurus 15379 R-BTA-9026405 https://reactome.org/PathwayBrowser/#/R-BTA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Bos taurus 15379 R-BTA-9026408 https://reactome.org/PathwayBrowser/#/R-BTA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Bos taurus 15379 R-BTA-9027043 https://reactome.org/PathwayBrowser/#/R-BTA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Bos taurus 15379 R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 15379 R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 15379 R-BTA-9027532 https://reactome.org/PathwayBrowser/#/R-BTA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Bos taurus 15379 R-BTA-9027607 https://reactome.org/PathwayBrowser/#/R-BTA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Bos taurus 15379 R-BTA-9027624 https://reactome.org/PathwayBrowser/#/R-BTA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Bos taurus 15379 R-BTA-9027627 https://reactome.org/PathwayBrowser/#/R-BTA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Bos taurus 15379 R-BTA-9027628 https://reactome.org/PathwayBrowser/#/R-BTA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Bos taurus 15379 R-BTA-9027633 https://reactome.org/PathwayBrowser/#/R-BTA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Bos taurus 15379 R-BTA-9028255 https://reactome.org/PathwayBrowser/#/R-BTA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Bos taurus 15379 R-BTA-9037761 https://reactome.org/PathwayBrowser/#/R-BTA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Bos taurus 15379 R-BTA-917891 https://reactome.org/PathwayBrowser/#/R-BTA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Bos taurus 15379 R-BTA-917933 https://reactome.org/PathwayBrowser/#/R-BTA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Bos taurus 15379 R-BTA-9629578 https://reactome.org/PathwayBrowser/#/R-BTA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Bos taurus 15379 R-BTA-9629591 https://reactome.org/PathwayBrowser/#/R-BTA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Bos taurus 15379 R-BTA-9629869 https://reactome.org/PathwayBrowser/#/R-BTA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Bos taurus 15379 R-BTA-9629888 https://reactome.org/PathwayBrowser/#/R-BTA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Bos taurus 15379 R-BTA-9629946 https://reactome.org/PathwayBrowser/#/R-BTA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Bos taurus 15379 R-BTA-9630022 https://reactome.org/PathwayBrowser/#/R-BTA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Bos taurus 15379 R-BTA-9630769 https://reactome.org/PathwayBrowser/#/R-BTA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Bos taurus 15379 R-BTA-9630967 https://reactome.org/PathwayBrowser/#/R-BTA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Bos taurus 15379 R-BTA-9630993 https://reactome.org/PathwayBrowser/#/R-BTA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Bos taurus 15379 R-BTA-9631356 https://reactome.org/PathwayBrowser/#/R-BTA-9631356 ASPH:Fe2+ hydroxylates an aspartate residue of F9 TAS Bos taurus 15379 R-BTA-965019 https://reactome.org/PathwayBrowser/#/R-BTA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Bos taurus 15379 R-BTA-965079 https://reactome.org/PathwayBrowser/#/R-BTA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Bos taurus 15379 R-BTA-9709360 https://reactome.org/PathwayBrowser/#/R-BTA-9709360 H2O2 reduces MetHb IEA Bos taurus 15379 R-BTA-9749986 https://reactome.org/PathwayBrowser/#/R-BTA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Bos taurus 15379 R-BTA-9750016 https://reactome.org/PathwayBrowser/#/R-BTA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Bos taurus 15379 R-BTA-9753285 https://reactome.org/PathwayBrowser/#/R-BTA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Bos taurus 15379 R-BTA-9756138 https://reactome.org/PathwayBrowser/#/R-BTA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Bos taurus 15379 R-BTA-9756162 https://reactome.org/PathwayBrowser/#/R-BTA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Bos taurus 15379 R-BTA-9756169 https://reactome.org/PathwayBrowser/#/R-BTA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Bos taurus 15379 R-BTA-9756180 https://reactome.org/PathwayBrowser/#/R-BTA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Bos taurus 15379 R-BTA-975635 https://reactome.org/PathwayBrowser/#/R-BTA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Bos taurus 15379 R-BTA-9758674 https://reactome.org/PathwayBrowser/#/R-BTA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Bos taurus 15379 R-BTA-9817575 https://reactome.org/PathwayBrowser/#/R-BTA-9817575 ERO1B oxidizes P4HB IEA Bos taurus 15379 R-CEL-1234165 https://reactome.org/PathwayBrowser/#/R-CEL-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 15379 R-CEL-1234173 https://reactome.org/PathwayBrowser/#/R-CEL-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 15379 R-CEL-1234177 https://reactome.org/PathwayBrowser/#/R-CEL-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 15379 R-CEL-1234181 https://reactome.org/PathwayBrowser/#/R-CEL-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 15379 R-CEL-1237119 https://reactome.org/PathwayBrowser/#/R-CEL-1237119 Acireductone is oxidized to MOB IEA Caenorhabditis elegans 15379 R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 15379 R-CEL-141348 https://reactome.org/PathwayBrowser/#/R-CEL-141348 PAO:FAD oxidises NASPM to PTCN IEA Caenorhabditis elegans 15379 R-CEL-141351 https://reactome.org/PathwayBrowser/#/R-CEL-141351 PAOX:FAD oxidises NASPN to SPM IEA Caenorhabditis elegans 15379 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 15379 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 15379 R-CEL-1562626 https://reactome.org/PathwayBrowser/#/R-CEL-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Caenorhabditis elegans 15379 R-CEL-156526 https://reactome.org/PathwayBrowser/#/R-CEL-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Caenorhabditis elegans 15379 R-CEL-1614544 https://reactome.org/PathwayBrowser/#/R-CEL-1614544 Sulfite is oxidized to sulfate IEA Caenorhabditis elegans 15379 R-CEL-1614605 https://reactome.org/PathwayBrowser/#/R-CEL-1614605 Persulfide sulfur is dioxygenated IEA Caenorhabditis elegans 15379 R-CEL-1614645 https://reactome.org/PathwayBrowser/#/R-CEL-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Caenorhabditis elegans 15379 R-CEL-1650808 https://reactome.org/PathwayBrowser/#/R-CEL-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Caenorhabditis elegans 15379 R-CEL-1655453 https://reactome.org/PathwayBrowser/#/R-CEL-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Caenorhabditis elegans 15379 R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 15379 R-CEL-192335 https://reactome.org/PathwayBrowser/#/R-CEL-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Caenorhabditis elegans 15379 R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 15379 R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 15379 R-CEL-193369 https://reactome.org/PathwayBrowser/#/R-CEL-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Caenorhabditis elegans 15379 R-CEL-1981104 https://reactome.org/PathwayBrowser/#/R-CEL-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Caenorhabditis elegans 15379 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 15379 R-CEL-2046084 https://reactome.org/PathwayBrowser/#/R-CEL-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Caenorhabditis elegans 15379 R-CEL-2046089 https://reactome.org/PathwayBrowser/#/R-CEL-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Caenorhabditis elegans 15379 R-CEL-2046092 https://reactome.org/PathwayBrowser/#/R-CEL-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Caenorhabditis elegans 15379 R-CEL-2046096 https://reactome.org/PathwayBrowser/#/R-CEL-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Caenorhabditis elegans 15379 R-CEL-2046097 https://reactome.org/PathwayBrowser/#/R-CEL-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Caenorhabditis elegans 15379 R-CEL-204662 https://reactome.org/PathwayBrowser/#/R-CEL-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Caenorhabditis elegans 15379 R-CEL-2066787 https://reactome.org/PathwayBrowser/#/R-CEL-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Caenorhabditis elegans 15379 R-CEL-209823 https://reactome.org/PathwayBrowser/#/R-CEL-209823 Tyrosine is hydroxylated to dopa IEA Caenorhabditis elegans 15379 R-CEL-209828 https://reactome.org/PathwayBrowser/#/R-CEL-209828 Tryptophan is hydroxylated IEA Caenorhabditis elegans 15379 R-CEL-209845 https://reactome.org/PathwayBrowser/#/R-CEL-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Caenorhabditis elegans 15379 R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 15379 R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 15379 R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 15379 R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 15379 R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 15379 R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 15379 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 15379 R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 15379 R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 15379 R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 15379 R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 15379 R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 15379 R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans 15379 R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Caenorhabditis elegans 15379 R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 15379 R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 15379 R-CEL-2172678 https://reactome.org/PathwayBrowser/#/R-CEL-2172678 PHF8 demethylates histone H4K20me1 IEA Caenorhabditis elegans 15379 R-CEL-3204311 https://reactome.org/PathwayBrowser/#/R-CEL-3204311 AOX1 oxidises PXL to PDXate IEA Caenorhabditis elegans 15379 R-CEL-3299680 https://reactome.org/PathwayBrowser/#/R-CEL-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Caenorhabditis elegans 15379 R-CEL-3299691 https://reactome.org/PathwayBrowser/#/R-CEL-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Caenorhabditis elegans 15379 R-CEL-3341294 https://reactome.org/PathwayBrowser/#/R-CEL-3341294 Superoxide reduces cytochrome c IEA Caenorhabditis elegans 15379 R-CEL-3777112 https://reactome.org/PathwayBrowser/#/R-CEL-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Caenorhabditis elegans 15379 R-CEL-389639 https://reactome.org/PathwayBrowser/#/R-CEL-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Caenorhabditis elegans 15379 R-CEL-389821 https://reactome.org/PathwayBrowser/#/R-CEL-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Caenorhabditis elegans 15379 R-CEL-389842 https://reactome.org/PathwayBrowser/#/R-CEL-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Caenorhabditis elegans 15379 R-CEL-389862 https://reactome.org/PathwayBrowser/#/R-CEL-389862 Conversion of glyoxylate to oxalate IEA Caenorhabditis elegans 15379 R-CEL-389889 https://reactome.org/PathwayBrowser/#/R-CEL-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Caenorhabditis elegans 15379 R-CEL-389891 https://reactome.org/PathwayBrowser/#/R-CEL-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Caenorhabditis elegans 15379 R-CEL-390256 https://reactome.org/PathwayBrowser/#/R-CEL-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Caenorhabditis elegans 15379 R-CEL-428259 https://reactome.org/PathwayBrowser/#/R-CEL-428259 DEGS1 dehydrogenates dihydroceramide IEA Caenorhabditis elegans 15379 R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 15379 R-CEL-4722133 https://reactome.org/PathwayBrowser/#/R-CEL-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-4724279 https://reactome.org/PathwayBrowser/#/R-CEL-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-4724284 https://reactome.org/PathwayBrowser/#/R-CEL-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-4754176 https://reactome.org/PathwayBrowser/#/R-CEL-4754176 JMJD6 demethylates MeR3-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-4754181 https://reactome.org/PathwayBrowser/#/R-CEL-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-4754187 https://reactome.org/PathwayBrowser/#/R-CEL-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-5164399 https://reactome.org/PathwayBrowser/#/R-CEL-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Caenorhabditis elegans 15379 R-CEL-5340214 https://reactome.org/PathwayBrowser/#/R-CEL-5340214 CYGB binds O2 IEA Caenorhabditis elegans 15379 R-CEL-5340226 https://reactome.org/PathwayBrowser/#/R-CEL-5340226 CYGB dioxygenates NO IEA Caenorhabditis elegans 15379 R-CEL-5423117 https://reactome.org/PathwayBrowser/#/R-CEL-5423117 PHF8 demethylates MeK21-histone H4 IEA Caenorhabditis elegans 15379 R-CEL-5423647 https://reactome.org/PathwayBrowser/#/R-CEL-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Caenorhabditis elegans 15379 R-CEL-5661114 https://reactome.org/PathwayBrowser/#/R-CEL-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-5661115 https://reactome.org/PathwayBrowser/#/R-CEL-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-5661116 https://reactome.org/PathwayBrowser/#/R-CEL-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-5661120 https://reactome.org/PathwayBrowser/#/R-CEL-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-5661121 https://reactome.org/PathwayBrowser/#/R-CEL-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-5661122 https://reactome.org/PathwayBrowser/#/R-CEL-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Caenorhabditis elegans 15379 R-CEL-5661124 https://reactome.org/PathwayBrowser/#/R-CEL-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Caenorhabditis elegans 15379 R-CEL-5661125 https://reactome.org/PathwayBrowser/#/R-CEL-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Caenorhabditis elegans 15379 R-CEL-5662692 https://reactome.org/PathwayBrowser/#/R-CEL-5662692 Dopa is oxidized to dopaquinone by TYR IEA Caenorhabditis elegans 15379 R-CEL-5678327 https://reactome.org/PathwayBrowser/#/R-CEL-5678327 MIOX oxidises Ins to GlcA IEA Caenorhabditis elegans 15379 R-CEL-5690565 https://reactome.org/PathwayBrowser/#/R-CEL-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15379 R-CEL-5691107 https://reactome.org/PathwayBrowser/#/R-CEL-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Caenorhabditis elegans 15379 R-CEL-5693681 https://reactome.org/PathwayBrowser/#/R-CEL-5693681 DUOX1,2 reduce O2 to H2O2 IEA Caenorhabditis elegans 15379 R-CEL-5693761 https://reactome.org/PathwayBrowser/#/R-CEL-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Caenorhabditis elegans 15379 R-CEL-5696119 https://reactome.org/PathwayBrowser/#/R-CEL-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Caenorhabditis elegans 15379 R-CEL-6783880 https://reactome.org/PathwayBrowser/#/R-CEL-6783880 PIPOX oxidises PPCA to P6C IEA Caenorhabditis elegans 15379 R-CEL-6786239 https://reactome.org/PathwayBrowser/#/R-CEL-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Caenorhabditis elegans 15379 R-CEL-6787811 https://reactome.org/PathwayBrowser/#/R-CEL-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Caenorhabditis elegans 15379 R-CEL-6810076 https://reactome.org/PathwayBrowser/#/R-CEL-6810076 DDO oxidizes D-Asp to OA IEA Caenorhabditis elegans 15379 R-CEL-6814153 https://reactome.org/PathwayBrowser/#/R-CEL-6814153 ADO oxidises 2AET to HTAU IEA Caenorhabditis elegans 15379 R-CEL-71118 https://reactome.org/PathwayBrowser/#/R-CEL-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Caenorhabditis elegans 15379 R-CEL-71163 https://reactome.org/PathwayBrowser/#/R-CEL-71163 HPD dioxygenates HPP IEA Caenorhabditis elegans 15379 R-CEL-71164 https://reactome.org/PathwayBrowser/#/R-CEL-71164 HGD dioxygenates homogentisate IEA Caenorhabditis elegans 15379 R-CEL-71188 https://reactome.org/PathwayBrowser/#/R-CEL-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Caenorhabditis elegans 15379 R-CEL-71200 https://reactome.org/PathwayBrowser/#/R-CEL-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Caenorhabditis elegans 15379 R-CEL-71218 https://reactome.org/PathwayBrowser/#/R-CEL-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Caenorhabditis elegans 15379 R-CEL-71241 https://reactome.org/PathwayBrowser/#/R-CEL-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Caenorhabditis elegans 15379 R-CEL-71261 https://reactome.org/PathwayBrowser/#/R-CEL-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Caenorhabditis elegans 15379 R-CEL-74247 https://reactome.org/PathwayBrowser/#/R-CEL-74247 XDH oxidizes hypoxanthine to form xanthine IEA Caenorhabditis elegans 15379 R-CEL-74258 https://reactome.org/PathwayBrowser/#/R-CEL-74258 XDH oxidizes xanthine to form urate IEA Caenorhabditis elegans 15379 R-CEL-76031 https://reactome.org/PathwayBrowser/#/R-CEL-76031 2 H2O2 => O2 + 2 H2O IEA Caenorhabditis elegans 15379 R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 15379 R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 15379 R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 15379 R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 15379 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 15379 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 15379 R-CEL-8847579 https://reactome.org/PathwayBrowser/#/R-CEL-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15379 R-CEL-8865107 https://reactome.org/PathwayBrowser/#/R-CEL-8865107 MICAL1 produces NADP+, H2O2 IEA Caenorhabditis elegans 15379 R-CEL-8878581 https://reactome.org/PathwayBrowser/#/R-CEL-8878581 TYRP1 oxidises DHICA to IQCA IEA Caenorhabditis elegans 15379 R-CEL-8981610 https://reactome.org/PathwayBrowser/#/R-CEL-8981610 Neuroglobin binds oxygen IEA Caenorhabditis elegans 15379 R-CEL-8981621 https://reactome.org/PathwayBrowser/#/R-CEL-8981621 Neuroglobin:oxygen dissociates IEA Caenorhabditis elegans 15379 R-CEL-8982617 https://reactome.org/PathwayBrowser/#/R-CEL-8982617 CYGB:O2 dissociates IEA Caenorhabditis elegans 15379 R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans 15379 R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 15379 R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 15379 R-CEL-9629869 https://reactome.org/PathwayBrowser/#/R-CEL-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Caenorhabditis elegans 15379 R-CEL-9629888 https://reactome.org/PathwayBrowser/#/R-CEL-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Caenorhabditis elegans 15379 R-CEL-9629946 https://reactome.org/PathwayBrowser/#/R-CEL-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Caenorhabditis elegans 15379 R-CEL-9630022 https://reactome.org/PathwayBrowser/#/R-CEL-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Caenorhabditis elegans 15379 R-CEL-9630769 https://reactome.org/PathwayBrowser/#/R-CEL-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Caenorhabditis elegans 15379 R-CEL-9630993 https://reactome.org/PathwayBrowser/#/R-CEL-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Caenorhabditis elegans 15379 R-CEL-965019 https://reactome.org/PathwayBrowser/#/R-CEL-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Caenorhabditis elegans 15379 R-CEL-965079 https://reactome.org/PathwayBrowser/#/R-CEL-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Caenorhabditis elegans 15379 R-CEL-9749986 https://reactome.org/PathwayBrowser/#/R-CEL-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Caenorhabditis elegans 15379 R-CEL-9750016 https://reactome.org/PathwayBrowser/#/R-CEL-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Caenorhabditis elegans 15379 R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans 15379 R-CEL-975635 https://reactome.org/PathwayBrowser/#/R-CEL-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Caenorhabditis elegans 15379 R-CEL-9817575 https://reactome.org/PathwayBrowser/#/R-CEL-9817575 ERO1B oxidizes P4HB IEA Caenorhabditis elegans 15379 R-CFA-1222376 https://reactome.org/PathwayBrowser/#/R-CFA-1222376 NOX2 generates superoxide from oxygen IEA Canis familiaris 15379 R-CFA-1234164 https://reactome.org/PathwayBrowser/#/R-CFA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Canis familiaris 15379 R-CFA-1234165 https://reactome.org/PathwayBrowser/#/R-CFA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 15379 R-CFA-1234173 https://reactome.org/PathwayBrowser/#/R-CFA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 15379 R-CFA-1234177 https://reactome.org/PathwayBrowser/#/R-CFA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 15379 R-CFA-1234181 https://reactome.org/PathwayBrowser/#/R-CFA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 15379 R-CFA-1236967 https://reactome.org/PathwayBrowser/#/R-CFA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Canis familiaris 15379 R-CFA-1237119 https://reactome.org/PathwayBrowser/#/R-CFA-1237119 Acireductone is oxidized to MOB IEA Canis familiaris 15379 R-CFA-1237325 https://reactome.org/PathwayBrowser/#/R-CFA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Canis familiaris 15379 R-CFA-1247668 https://reactome.org/PathwayBrowser/#/R-CFA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Canis familiaris 15379 R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 15379 R-CFA-140355 https://reactome.org/PathwayBrowser/#/R-CFA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Canis familiaris 15379 R-CFA-141186 https://reactome.org/PathwayBrowser/#/R-CFA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Canis familiaris 15379 R-CFA-141200 https://reactome.org/PathwayBrowser/#/R-CFA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Canis familiaris 15379 R-CFA-141202 https://reactome.org/PathwayBrowser/#/R-CFA-141202 MAOB:FAD oxidatively deaminates TYR IEA Canis familiaris 15379 R-CFA-141341 https://reactome.org/PathwayBrowser/#/R-CFA-141341 SMOX-3 oxidises SPN to SPM IEA Canis familiaris 15379 R-CFA-141348 https://reactome.org/PathwayBrowser/#/R-CFA-141348 PAO:FAD oxidises NASPM to PTCN IEA Canis familiaris 15379 R-CFA-141351 https://reactome.org/PathwayBrowser/#/R-CFA-141351 PAOX:FAD oxidises NASPN to SPM IEA Canis familiaris 15379 R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 15379 R-CFA-1562626 https://reactome.org/PathwayBrowser/#/R-CFA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Canis familiaris 15379 R-CFA-156526 https://reactome.org/PathwayBrowser/#/R-CFA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Canis familiaris 15379 R-CFA-159752 https://reactome.org/PathwayBrowser/#/R-CFA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Canis familiaris 15379 R-CFA-159761 https://reactome.org/PathwayBrowser/#/R-CFA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Canis familiaris 15379 R-CFA-159795 https://reactome.org/PathwayBrowser/#/R-CFA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Canis familiaris 15379 R-CFA-159803 https://reactome.org/PathwayBrowser/#/R-CFA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Canis familiaris 15379 R-CFA-159819 https://reactome.org/PathwayBrowser/#/R-CFA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Canis familiaris 15379 R-CFA-159826 https://reactome.org/PathwayBrowser/#/R-CFA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Canis familiaris 15379 R-CFA-1614544 https://reactome.org/PathwayBrowser/#/R-CFA-1614544 Sulfite is oxidized to sulfate IEA Canis familiaris 15379 R-CFA-1614605 https://reactome.org/PathwayBrowser/#/R-CFA-1614605 Persulfide sulfur is dioxygenated IEA Canis familiaris 15379 R-CFA-1614645 https://reactome.org/PathwayBrowser/#/R-CFA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Canis familiaris 15379 R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 15379 R-CFA-1650808 https://reactome.org/PathwayBrowser/#/R-CFA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Canis familiaris 15379 R-CFA-1655453 https://reactome.org/PathwayBrowser/#/R-CFA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Canis familiaris 15379 R-CFA-189398 https://reactome.org/PathwayBrowser/#/R-CFA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Canis familiaris 15379 R-CFA-189421 https://reactome.org/PathwayBrowser/#/R-CFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Canis familiaris 15379 R-CFA-189423 https://reactome.org/PathwayBrowser/#/R-CFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Canis familiaris 15379 R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 15379 R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 15379 R-CFA-191999 https://reactome.org/PathwayBrowser/#/R-CFA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Canis familiaris 15379 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 15379 R-CFA-192054 https://reactome.org/PathwayBrowser/#/R-CFA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Canis familiaris 15379 R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 15379 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 15379 R-CFA-192123 https://reactome.org/PathwayBrowser/#/R-CFA-192123 CYP27A1 27-hydroxylates CHOL IEA Canis familiaris 15379 R-CFA-192157 https://reactome.org/PathwayBrowser/#/R-CFA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Canis familiaris 15379 R-CFA-192178 https://reactome.org/PathwayBrowser/#/R-CFA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Canis familiaris 15379 R-CFA-192335 https://reactome.org/PathwayBrowser/#/R-CFA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Canis familiaris 15379 R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 15379 R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 15379 R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 15379 R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 15379 R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 15379 R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 15379 R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 15379 R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 15379 R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 15379 R-CFA-193369 https://reactome.org/PathwayBrowser/#/R-CFA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Canis familiaris 15379 R-CFA-193393 https://reactome.org/PathwayBrowser/#/R-CFA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Canis familiaris 15379 R-CFA-193460 https://reactome.org/PathwayBrowser/#/R-CFA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Canis familiaris 15379 R-CFA-193709 https://reactome.org/PathwayBrowser/#/R-CFA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Canis familiaris 15379 R-CFA-193713 https://reactome.org/PathwayBrowser/#/R-CFA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Canis familiaris 15379 R-CFA-193719 https://reactome.org/PathwayBrowser/#/R-CFA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 15379 R-CFA-193737 https://reactome.org/PathwayBrowser/#/R-CFA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Canis familiaris 15379 R-CFA-193780 https://reactome.org/PathwayBrowser/#/R-CFA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Canis familiaris 15379 R-CFA-193787 https://reactome.org/PathwayBrowser/#/R-CFA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Canis familiaris 15379 R-CFA-193792 https://reactome.org/PathwayBrowser/#/R-CFA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Canis familiaris 15379 R-CFA-193845 https://reactome.org/PathwayBrowser/#/R-CFA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Canis familiaris 15379 R-CFA-193964 https://reactome.org/PathwayBrowser/#/R-CFA-193964 CYP21A2 21-hydroxylates PROG IEA Canis familiaris 15379 R-CFA-193965 https://reactome.org/PathwayBrowser/#/R-CFA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Canis familiaris 15379 R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 15379 R-CFA-193995 https://reactome.org/PathwayBrowser/#/R-CFA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Canis familiaris 15379 R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 15379 R-CFA-194017 https://reactome.org/PathwayBrowser/#/R-CFA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Canis familiaris 15379 R-CFA-194641 https://reactome.org/PathwayBrowser/#/R-CFA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15379 R-CFA-194669 https://reactome.org/PathwayBrowser/#/R-CFA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15379 R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 15379 R-CFA-195664 https://reactome.org/PathwayBrowser/#/R-CFA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Canis familiaris 15379 R-CFA-1980233 https://reactome.org/PathwayBrowser/#/R-CFA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Canis familiaris 15379 R-CFA-1981104 https://reactome.org/PathwayBrowser/#/R-CFA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Canis familiaris 15379 R-CFA-198563 https://reactome.org/PathwayBrowser/#/R-CFA-198563 IDO1 dioxygenates L-Trp to NFK IEA Canis familiaris 15379 R-CFA-2002466 https://reactome.org/PathwayBrowser/#/R-CFA-2002466 Formation of allysine by LOX IEA Canis familiaris 15379 R-CFA-2046084 https://reactome.org/PathwayBrowser/#/R-CFA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Canis familiaris 15379 R-CFA-2046089 https://reactome.org/PathwayBrowser/#/R-CFA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Canis familiaris 15379 R-CFA-2046092 https://reactome.org/PathwayBrowser/#/R-CFA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Canis familiaris 15379 R-CFA-2046096 https://reactome.org/PathwayBrowser/#/R-CFA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Canis familiaris 15379 R-CFA-2046097 https://reactome.org/PathwayBrowser/#/R-CFA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 15379 R-CFA-204662 https://reactome.org/PathwayBrowser/#/R-CFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Canis familiaris 15379 R-CFA-2066787 https://reactome.org/PathwayBrowser/#/R-CFA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Canis familiaris 15379 R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 15379 R-CFA-209823 https://reactome.org/PathwayBrowser/#/R-CFA-209823 Tyrosine is hydroxylated to dopa IEA Canis familiaris 15379 R-CFA-209828 https://reactome.org/PathwayBrowser/#/R-CFA-209828 Tryptophan is hydroxylated IEA Canis familiaris 15379 R-CFA-209845 https://reactome.org/PathwayBrowser/#/R-CFA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Canis familiaris 15379 R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 15379 R-CFA-209891 https://reactome.org/PathwayBrowser/#/R-CFA-209891 Dopamine is oxidised to noradrenaline IEA Canis familiaris 15379 R-CFA-211873 https://reactome.org/PathwayBrowser/#/R-CFA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Canis familiaris 15379 R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 15379 R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 15379 R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 15379 R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 15379 R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 15379 R-CFA-211923 https://reactome.org/PathwayBrowser/#/R-CFA-211923 CYP26C1 4-hydroxylates 9cRA IEA Canis familiaris 15379 R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 15379 R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 15379 R-CFA-211950 https://reactome.org/PathwayBrowser/#/R-CFA-211950 CYP24A1 24-hydroxylates CTL IEA Canis familiaris 15379 R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 15379 R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 15379 R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 15379 R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 15379 R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 15379 R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 15379 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 15379 R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 15379 R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 15379 R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 15379 R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 15379 R-CFA-2160492 https://reactome.org/PathwayBrowser/#/R-CFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Canis familiaris 15379 R-CFA-2161745 https://reactome.org/PathwayBrowser/#/R-CFA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15379 R-CFA-2161775 https://reactome.org/PathwayBrowser/#/R-CFA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Canis familiaris 15379 R-CFA-2161792 https://reactome.org/PathwayBrowser/#/R-CFA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15379 R-CFA-2161794 https://reactome.org/PathwayBrowser/#/R-CFA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Canis familiaris 15379 R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Canis familiaris 15379 R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 15379 R-CFA-2161890 https://reactome.org/PathwayBrowser/#/R-CFA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Canis familiaris 15379 R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Canis familiaris 15379 R-CFA-2161907 https://reactome.org/PathwayBrowser/#/R-CFA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Canis familiaris 15379 R-CFA-2161917 https://reactome.org/PathwayBrowser/#/R-CFA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Canis familiaris 15379 R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 15379 R-CFA-2161950 https://reactome.org/PathwayBrowser/#/R-CFA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Canis familiaris 15379 R-CFA-2161951 https://reactome.org/PathwayBrowser/#/R-CFA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Canis familiaris 15379 R-CFA-2161964 https://reactome.org/PathwayBrowser/#/R-CFA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Canis familiaris 15379 R-CFA-2162002 https://reactome.org/PathwayBrowser/#/R-CFA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Canis familiaris 15379 R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 15379 R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 15379 R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 15379 R-CFA-2172678 https://reactome.org/PathwayBrowser/#/R-CFA-2172678 PHF8 demethylates histone H4K20me1 IEA Canis familiaris 15379 R-CFA-2230938 https://reactome.org/PathwayBrowser/#/R-CFA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Canis familiaris 15379 R-CFA-2309787 https://reactome.org/PathwayBrowser/#/R-CFA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Canis familiaris 15379 R-CFA-2395340 https://reactome.org/PathwayBrowser/#/R-CFA-2395340 Formation of hydroxyallysine by LOX IEA Canis familiaris 15379 R-CFA-265296 https://reactome.org/PathwayBrowser/#/R-CFA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Canis familiaris 15379 R-CFA-3299680 https://reactome.org/PathwayBrowser/#/R-CFA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Canis familiaris 15379 R-CFA-3299682 https://reactome.org/PathwayBrowser/#/R-CFA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Canis familiaris 15379 R-CFA-3299691 https://reactome.org/PathwayBrowser/#/R-CFA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Canis familiaris 15379 R-CFA-3341294 https://reactome.org/PathwayBrowser/#/R-CFA-3341294 Superoxide reduces cytochrome c IEA Canis familiaris 15379 R-CFA-374909 https://reactome.org/PathwayBrowser/#/R-CFA-374909 Catabolism of Noradrenaline IEA Canis familiaris 15379 R-CFA-3777112 https://reactome.org/PathwayBrowser/#/R-CFA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Canis familiaris 15379 R-CFA-379382 https://reactome.org/PathwayBrowser/#/R-CFA-379382 MAOA:FAD deaminates DA to DOPAC IEA Canis familiaris 15379 R-CFA-379395 https://reactome.org/PathwayBrowser/#/R-CFA-379395 MAOA:FAD deaminates 3MT to HVA IEA Canis familiaris 15379 R-CFA-389639 https://reactome.org/PathwayBrowser/#/R-CFA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Canis familiaris 15379 R-CFA-389821 https://reactome.org/PathwayBrowser/#/R-CFA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Canis familiaris 15379 R-CFA-389842 https://reactome.org/PathwayBrowser/#/R-CFA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Canis familiaris 15379 R-CFA-389862 https://reactome.org/PathwayBrowser/#/R-CFA-389862 Conversion of glyoxylate to oxalate IEA Canis familiaris 15379 R-CFA-389889 https://reactome.org/PathwayBrowser/#/R-CFA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Canis familiaris 15379 R-CFA-389891 https://reactome.org/PathwayBrowser/#/R-CFA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Canis familiaris 15379 R-CFA-390256 https://reactome.org/PathwayBrowser/#/R-CFA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Canis familiaris 15379 R-CFA-418436 https://reactome.org/PathwayBrowser/#/R-CFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Canis familiaris 15379 R-CFA-428259 https://reactome.org/PathwayBrowser/#/R-CFA-428259 DEGS1 dehydrogenates dihydroceramide IEA Canis familiaris 15379 R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 15379 R-CFA-4722133 https://reactome.org/PathwayBrowser/#/R-CFA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Canis familiaris 15379 R-CFA-4724279 https://reactome.org/PathwayBrowser/#/R-CFA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Canis familiaris 15379 R-CFA-4724284 https://reactome.org/PathwayBrowser/#/R-CFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Canis familiaris 15379 R-CFA-4754176 https://reactome.org/PathwayBrowser/#/R-CFA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Canis familiaris 15379 R-CFA-4754181 https://reactome.org/PathwayBrowser/#/R-CFA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Canis familiaris 15379 R-CFA-4754187 https://reactome.org/PathwayBrowser/#/R-CFA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Canis familiaris 15379 R-CFA-5164399 https://reactome.org/PathwayBrowser/#/R-CFA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Canis familiaris 15379 R-CFA-5218841 https://reactome.org/PathwayBrowser/#/R-CFA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Canis familiaris 15379 R-CFA-5340214 https://reactome.org/PathwayBrowser/#/R-CFA-5340214 CYGB binds O2 IEA Canis familiaris 15379 R-CFA-5340226 https://reactome.org/PathwayBrowser/#/R-CFA-5340226 CYGB dioxygenates NO IEA Canis familiaris 15379 R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 15379 R-CFA-5423117 https://reactome.org/PathwayBrowser/#/R-CFA-5423117 PHF8 demethylates MeK21-histone H4 IEA Canis familiaris 15379 R-CFA-5423647 https://reactome.org/PathwayBrowser/#/R-CFA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Canis familiaris 15379 R-CFA-5423664 https://reactome.org/PathwayBrowser/#/R-CFA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Canis familiaris 15379 R-CFA-5423672 https://reactome.org/PathwayBrowser/#/R-CFA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Canis familiaris 15379 R-CFA-5602295 https://reactome.org/PathwayBrowser/#/R-CFA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Canis familiaris 15379 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 15379 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 15379 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 15379 R-CFA-5661114 https://reactome.org/PathwayBrowser/#/R-CFA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Canis familiaris 15379 R-CFA-5661115 https://reactome.org/PathwayBrowser/#/R-CFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Canis familiaris 15379 R-CFA-5661116 https://reactome.org/PathwayBrowser/#/R-CFA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Canis familiaris 15379 R-CFA-5661120 https://reactome.org/PathwayBrowser/#/R-CFA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Canis familiaris 15379 R-CFA-5661121 https://reactome.org/PathwayBrowser/#/R-CFA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Canis familiaris 15379 R-CFA-5661122 https://reactome.org/PathwayBrowser/#/R-CFA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Canis familiaris 15379 R-CFA-5661124 https://reactome.org/PathwayBrowser/#/R-CFA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Canis familiaris 15379 R-CFA-5661125 https://reactome.org/PathwayBrowser/#/R-CFA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Canis familiaris 15379 R-CFA-5662692 https://reactome.org/PathwayBrowser/#/R-CFA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Canis familiaris 15379 R-CFA-5668629 https://reactome.org/PathwayBrowser/#/R-CFA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Canis familiaris 15379 R-CFA-5668718 https://reactome.org/PathwayBrowser/#/R-CFA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 15379 R-CFA-5668731 https://reactome.org/PathwayBrowser/#/R-CFA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 15379 R-CFA-5678327 https://reactome.org/PathwayBrowser/#/R-CFA-5678327 MIOX oxidises Ins to GlcA IEA Canis familiaris 15379 R-CFA-5690565 https://reactome.org/PathwayBrowser/#/R-CFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15379 R-CFA-5691107 https://reactome.org/PathwayBrowser/#/R-CFA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Canis familiaris 15379 R-CFA-5693681 https://reactome.org/PathwayBrowser/#/R-CFA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Canis familiaris 15379 R-CFA-5693761 https://reactome.org/PathwayBrowser/#/R-CFA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Canis familiaris 15379 R-CFA-5696119 https://reactome.org/PathwayBrowser/#/R-CFA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Canis familiaris 15379 R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 15379 R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 15379 R-CFA-6783880 https://reactome.org/PathwayBrowser/#/R-CFA-6783880 PIPOX oxidises PPCA to P6C IEA Canis familiaris 15379 R-CFA-6786239 https://reactome.org/PathwayBrowser/#/R-CFA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Canis familiaris 15379 R-CFA-6787811 https://reactome.org/PathwayBrowser/#/R-CFA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Canis familiaris 15379 R-CFA-6789092 https://reactome.org/PathwayBrowser/#/R-CFA-6789092 NOX2 generates superoxide anion from oxygen IEA Canis familiaris 15379 R-CFA-6807053 https://reactome.org/PathwayBrowser/#/R-CFA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Canis familiaris 15379 R-CFA-6807214 https://reactome.org/PathwayBrowser/#/R-CFA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Canis familiaris 15379 R-CFA-6807557 https://reactome.org/PathwayBrowser/#/R-CFA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Canis familiaris 15379 R-CFA-6810076 https://reactome.org/PathwayBrowser/#/R-CFA-6810076 DDO oxidizes D-Asp to OA IEA Canis familiaris 15379 R-CFA-6814153 https://reactome.org/PathwayBrowser/#/R-CFA-6814153 ADO oxidises 2AET to HTAU IEA Canis familiaris 15379 R-CFA-71118 https://reactome.org/PathwayBrowser/#/R-CFA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Canis familiaris 15379 R-CFA-71163 https://reactome.org/PathwayBrowser/#/R-CFA-71163 HPD dioxygenates HPP IEA Canis familiaris 15379 R-CFA-71164 https://reactome.org/PathwayBrowser/#/R-CFA-71164 HGD dioxygenates homogentisate IEA Canis familiaris 15379 R-CFA-71188 https://reactome.org/PathwayBrowser/#/R-CFA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Canis familiaris 15379 R-CFA-71200 https://reactome.org/PathwayBrowser/#/R-CFA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Canis familiaris 15379 R-CFA-71218 https://reactome.org/PathwayBrowser/#/R-CFA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Canis familiaris 15379 R-CFA-71241 https://reactome.org/PathwayBrowser/#/R-CFA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Canis familiaris 15379 R-CFA-71261 https://reactome.org/PathwayBrowser/#/R-CFA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Canis familiaris 15379 R-CFA-74247 https://reactome.org/PathwayBrowser/#/R-CFA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Canis familiaris 15379 R-CFA-74258 https://reactome.org/PathwayBrowser/#/R-CFA-74258 XDH oxidizes xanthine to form urate IEA Canis familiaris 15379 R-CFA-76031 https://reactome.org/PathwayBrowser/#/R-CFA-76031 2 H2O2 => O2 + 2 H2O IEA Canis familiaris 15379 R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 15379 R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 15379 R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 15379 R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 15379 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 15379 R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 15379 R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 15379 R-CFA-8847579 https://reactome.org/PathwayBrowser/#/R-CFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15379 R-CFA-8878581 https://reactome.org/PathwayBrowser/#/R-CFA-8878581 TYRP1 oxidises DHICA to IQCA IEA Canis familiaris 15379 R-CFA-888614 https://reactome.org/PathwayBrowser/#/R-CFA-888614 IDO2 dioxygenates L-Trp to NFK IEA Canis familiaris 15379 R-CFA-8953398 https://reactome.org/PathwayBrowser/#/R-CFA-8953398 PIR oxygenates quercetin IEA Canis familiaris 15379 R-CFA-8956458 https://reactome.org/PathwayBrowser/#/R-CFA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Canis familiaris 15379 R-CFA-8981606 https://reactome.org/PathwayBrowser/#/R-CFA-8981606 Myoglobin binds oxygen IEA Canis familiaris 15379 R-CFA-8981610 https://reactome.org/PathwayBrowser/#/R-CFA-8981610 Neuroglobin binds oxygen IEA Canis familiaris 15379 R-CFA-8981621 https://reactome.org/PathwayBrowser/#/R-CFA-8981621 Neuroglobin:oxygen dissociates IEA Canis familiaris 15379 R-CFA-8981622 https://reactome.org/PathwayBrowser/#/R-CFA-8981622 Myoglobin:oxygen dissociates IEA Canis familiaris 15379 R-CFA-8982617 https://reactome.org/PathwayBrowser/#/R-CFA-8982617 CYGB:O2 dissociates IEA Canis familiaris 15379 R-CFA-9018858 https://reactome.org/PathwayBrowser/#/R-CFA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Canis familiaris 15379 R-CFA-9018859 https://reactome.org/PathwayBrowser/#/R-CFA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Canis familiaris 15379 R-CFA-9018863 https://reactome.org/PathwayBrowser/#/R-CFA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Canis familiaris 15379 R-CFA-9018880 https://reactome.org/PathwayBrowser/#/R-CFA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Canis familiaris 15379 R-CFA-9018894 https://reactome.org/PathwayBrowser/#/R-CFA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Canis familiaris 15379 R-CFA-9018907 https://reactome.org/PathwayBrowser/#/R-CFA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Canis familiaris 15379 R-CFA-9020251 https://reactome.org/PathwayBrowser/#/R-CFA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Canis familiaris 15379 R-CFA-9020259 https://reactome.org/PathwayBrowser/#/R-CFA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Canis familiaris 15379 R-CFA-9020261 https://reactome.org/PathwayBrowser/#/R-CFA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Canis familiaris 15379 R-CFA-9020264 https://reactome.org/PathwayBrowser/#/R-CFA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Canis familiaris 15379 R-CFA-9020274 https://reactome.org/PathwayBrowser/#/R-CFA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Canis familiaris 15379 R-CFA-9020275 https://reactome.org/PathwayBrowser/#/R-CFA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Canis familiaris 15379 R-CFA-9020282 https://reactome.org/PathwayBrowser/#/R-CFA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Canis familiaris 15379 R-CFA-9020610 https://reactome.org/PathwayBrowser/#/R-CFA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Canis familiaris 15379 R-CFA-9024872 https://reactome.org/PathwayBrowser/#/R-CFA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Canis familiaris 15379 R-CFA-9024997 https://reactome.org/PathwayBrowser/#/R-CFA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Canis familiaris 15379 R-CFA-9025152 https://reactome.org/PathwayBrowser/#/R-CFA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Canis familiaris 15379 R-CFA-9025957 https://reactome.org/PathwayBrowser/#/R-CFA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Canis familiaris 15379 R-CFA-9025996 https://reactome.org/PathwayBrowser/#/R-CFA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Canis familiaris 15379 R-CFA-9026003 https://reactome.org/PathwayBrowser/#/R-CFA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Canis familiaris 15379 R-CFA-9026005 https://reactome.org/PathwayBrowser/#/R-CFA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Canis familiaris 15379 R-CFA-9026006 https://reactome.org/PathwayBrowser/#/R-CFA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Canis familiaris 15379 R-CFA-9026405 https://reactome.org/PathwayBrowser/#/R-CFA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Canis familiaris 15379 R-CFA-9026408 https://reactome.org/PathwayBrowser/#/R-CFA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Canis familiaris 15379 R-CFA-9027043 https://reactome.org/PathwayBrowser/#/R-CFA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Canis familiaris 15379 R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 15379 R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 15379 R-CFA-9027532 https://reactome.org/PathwayBrowser/#/R-CFA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Canis familiaris 15379 R-CFA-9027607 https://reactome.org/PathwayBrowser/#/R-CFA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Canis familiaris 15379 R-CFA-9027624 https://reactome.org/PathwayBrowser/#/R-CFA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Canis familiaris 15379 R-CFA-9027627 https://reactome.org/PathwayBrowser/#/R-CFA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Canis familiaris 15379 R-CFA-9027628 https://reactome.org/PathwayBrowser/#/R-CFA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Canis familiaris 15379 R-CFA-9027633 https://reactome.org/PathwayBrowser/#/R-CFA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Canis familiaris 15379 R-CFA-9028255 https://reactome.org/PathwayBrowser/#/R-CFA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Canis familiaris 15379 R-CFA-917891 https://reactome.org/PathwayBrowser/#/R-CFA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Canis familiaris 15379 R-CFA-917933 https://reactome.org/PathwayBrowser/#/R-CFA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Canis familiaris 15379 R-CFA-9629578 https://reactome.org/PathwayBrowser/#/R-CFA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Canis familiaris 15379 R-CFA-9629591 https://reactome.org/PathwayBrowser/#/R-CFA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Canis familiaris 15379 R-CFA-9629869 https://reactome.org/PathwayBrowser/#/R-CFA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Canis familiaris 15379 R-CFA-9629888 https://reactome.org/PathwayBrowser/#/R-CFA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Canis familiaris 15379 R-CFA-9629946 https://reactome.org/PathwayBrowser/#/R-CFA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Canis familiaris 15379 R-CFA-9630022 https://reactome.org/PathwayBrowser/#/R-CFA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Canis familiaris 15379 R-CFA-9630769 https://reactome.org/PathwayBrowser/#/R-CFA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Canis familiaris 15379 R-CFA-9630967 https://reactome.org/PathwayBrowser/#/R-CFA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Canis familiaris 15379 R-CFA-9630993 https://reactome.org/PathwayBrowser/#/R-CFA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Canis familiaris 15379 R-CFA-965019 https://reactome.org/PathwayBrowser/#/R-CFA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Canis familiaris 15379 R-CFA-965079 https://reactome.org/PathwayBrowser/#/R-CFA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Canis familiaris 15379 R-CFA-9709360 https://reactome.org/PathwayBrowser/#/R-CFA-9709360 H2O2 reduces MetHb IEA Canis familiaris 15379 R-CFA-9749986 https://reactome.org/PathwayBrowser/#/R-CFA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Canis familiaris 15379 R-CFA-9750016 https://reactome.org/PathwayBrowser/#/R-CFA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Canis familiaris 15379 R-CFA-9753285 https://reactome.org/PathwayBrowser/#/R-CFA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Canis familiaris 15379 R-CFA-9756138 https://reactome.org/PathwayBrowser/#/R-CFA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Canis familiaris 15379 R-CFA-9756162 https://reactome.org/PathwayBrowser/#/R-CFA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Canis familiaris 15379 R-CFA-9756169 https://reactome.org/PathwayBrowser/#/R-CFA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Canis familiaris 15379 R-CFA-9756180 https://reactome.org/PathwayBrowser/#/R-CFA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Canis familiaris 15379 R-CFA-975635 https://reactome.org/PathwayBrowser/#/R-CFA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Canis familiaris 15379 R-CFA-9758674 https://reactome.org/PathwayBrowser/#/R-CFA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Canis familiaris 15379 R-CFA-9817575 https://reactome.org/PathwayBrowser/#/R-CFA-9817575 ERO1B oxidizes P4HB IEA Canis familiaris 15379 R-DDI-1237119 https://reactome.org/PathwayBrowser/#/R-DDI-1237119 Acireductone is oxidized to MOB IEA Dictyostelium discoideum 15379 R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 15379 R-DDI-141186 https://reactome.org/PathwayBrowser/#/R-DDI-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Dictyostelium discoideum 15379 R-DDI-141200 https://reactome.org/PathwayBrowser/#/R-DDI-141200 MAOB:FAD oxidatively deaminates of PEA IEA Dictyostelium discoideum 15379 R-DDI-141202 https://reactome.org/PathwayBrowser/#/R-DDI-141202 MAOB:FAD oxidatively deaminates TYR IEA Dictyostelium discoideum 15379 R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 15379 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 15379 R-DDI-156526 https://reactome.org/PathwayBrowser/#/R-DDI-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Dictyostelium discoideum 15379 R-DDI-1614544 https://reactome.org/PathwayBrowser/#/R-DDI-1614544 Sulfite is oxidized to sulfate IEA Dictyostelium discoideum 15379 R-DDI-1614645 https://reactome.org/PathwayBrowser/#/R-DDI-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Dictyostelium discoideum 15379 R-DDI-1655453 https://reactome.org/PathwayBrowser/#/R-DDI-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Dictyostelium discoideum 15379 R-DDI-189421 https://reactome.org/PathwayBrowser/#/R-DDI-189421 CPO transforms COPRO3 to PPGEN9 IEA Dictyostelium discoideum 15379 R-DDI-189423 https://reactome.org/PathwayBrowser/#/R-DDI-189423 PPO oxidises PPGEN9 to PRIN9 IEA Dictyostelium discoideum 15379 R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 15379 R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 15379 R-DDI-192335 https://reactome.org/PathwayBrowser/#/R-DDI-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Dictyostelium discoideum 15379 R-DDI-193369 https://reactome.org/PathwayBrowser/#/R-DDI-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Dictyostelium discoideum 15379 R-DDI-193964 https://reactome.org/PathwayBrowser/#/R-DDI-193964 CYP21A2 21-hydroxylates PROG IEA Dictyostelium discoideum 15379 R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 15379 R-DDI-194641 https://reactome.org/PathwayBrowser/#/R-DDI-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15379 R-DDI-194669 https://reactome.org/PathwayBrowser/#/R-DDI-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15379 R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 15379 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 15379 R-DDI-204662 https://reactome.org/PathwayBrowser/#/R-DDI-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Dictyostelium discoideum 15379 R-DDI-2066787 https://reactome.org/PathwayBrowser/#/R-DDI-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Dictyostelium discoideum 15379 R-DDI-209823 https://reactome.org/PathwayBrowser/#/R-DDI-209823 Tyrosine is hydroxylated to dopa IEA Dictyostelium discoideum 15379 R-DDI-209828 https://reactome.org/PathwayBrowser/#/R-DDI-209828 Tryptophan is hydroxylated IEA Dictyostelium discoideum 15379 R-DDI-209845 https://reactome.org/PathwayBrowser/#/R-DDI-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Dictyostelium discoideum 15379 R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 15379 R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 15379 R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 15379 R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 15379 R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 15379 R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 15379 R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 15379 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 15379 R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 15379 R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 15379 R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 15379 R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 15379 R-DDI-2160492 https://reactome.org/PathwayBrowser/#/R-DDI-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Dictyostelium discoideum 15379 R-DDI-2161775 https://reactome.org/PathwayBrowser/#/R-DDI-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Dictyostelium discoideum 15379 R-DDI-2161794 https://reactome.org/PathwayBrowser/#/R-DDI-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Dictyostelium discoideum 15379 R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 15379 R-DDI-2161890 https://reactome.org/PathwayBrowser/#/R-DDI-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Dictyostelium discoideum 15379 R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Dictyostelium discoideum 15379 R-DDI-2161907 https://reactome.org/PathwayBrowser/#/R-DDI-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Dictyostelium discoideum 15379 R-DDI-2161917 https://reactome.org/PathwayBrowser/#/R-DDI-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Dictyostelium discoideum 15379 R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 15379 R-DDI-2161950 https://reactome.org/PathwayBrowser/#/R-DDI-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Dictyostelium discoideum 15379 R-DDI-2161964 https://reactome.org/PathwayBrowser/#/R-DDI-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Dictyostelium discoideum 15379 R-DDI-2162002 https://reactome.org/PathwayBrowser/#/R-DDI-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Dictyostelium discoideum 15379 R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 15379 R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 15379 R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 15379 R-DDI-2172678 https://reactome.org/PathwayBrowser/#/R-DDI-2172678 PHF8 demethylates histone H4K20me1 IEA Dictyostelium discoideum 15379 R-DDI-265296 https://reactome.org/PathwayBrowser/#/R-DDI-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Dictyostelium discoideum 15379 R-DDI-3204311 https://reactome.org/PathwayBrowser/#/R-DDI-3204311 AOX1 oxidises PXL to PDXate IEA Dictyostelium discoideum 15379 R-DDI-3299680 https://reactome.org/PathwayBrowser/#/R-DDI-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Dictyostelium discoideum 15379 R-DDI-3299682 https://reactome.org/PathwayBrowser/#/R-DDI-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Dictyostelium discoideum 15379 R-DDI-3299691 https://reactome.org/PathwayBrowser/#/R-DDI-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Dictyostelium discoideum 15379 R-DDI-3341294 https://reactome.org/PathwayBrowser/#/R-DDI-3341294 Superoxide reduces cytochrome c IEA Dictyostelium discoideum 15379 R-DDI-374909 https://reactome.org/PathwayBrowser/#/R-DDI-374909 Catabolism of Noradrenaline IEA Dictyostelium discoideum 15379 R-DDI-3777112 https://reactome.org/PathwayBrowser/#/R-DDI-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Dictyostelium discoideum 15379 R-DDI-379382 https://reactome.org/PathwayBrowser/#/R-DDI-379382 MAOA:FAD deaminates DA to DOPAC IEA Dictyostelium discoideum 15379 R-DDI-379395 https://reactome.org/PathwayBrowser/#/R-DDI-379395 MAOA:FAD deaminates 3MT to HVA IEA Dictyostelium discoideum 15379 R-DDI-389639 https://reactome.org/PathwayBrowser/#/R-DDI-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Dictyostelium discoideum 15379 R-DDI-389821 https://reactome.org/PathwayBrowser/#/R-DDI-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Dictyostelium discoideum 15379 R-DDI-389842 https://reactome.org/PathwayBrowser/#/R-DDI-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Dictyostelium discoideum 15379 R-DDI-389862 https://reactome.org/PathwayBrowser/#/R-DDI-389862 Conversion of glyoxylate to oxalate IEA Dictyostelium discoideum 15379 R-DDI-389889 https://reactome.org/PathwayBrowser/#/R-DDI-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Dictyostelium discoideum 15379 R-DDI-389891 https://reactome.org/PathwayBrowser/#/R-DDI-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Dictyostelium discoideum 15379 R-DDI-390256 https://reactome.org/PathwayBrowser/#/R-DDI-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Dictyostelium discoideum 15379 R-DDI-418436 https://reactome.org/PathwayBrowser/#/R-DDI-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Dictyostelium discoideum 15379 R-DDI-428259 https://reactome.org/PathwayBrowser/#/R-DDI-428259 DEGS1 dehydrogenates dihydroceramide IEA Dictyostelium discoideum 15379 R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 15379 R-DDI-4754181 https://reactome.org/PathwayBrowser/#/R-DDI-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Dictyostelium discoideum 15379 R-DDI-4754187 https://reactome.org/PathwayBrowser/#/R-DDI-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Dictyostelium discoideum 15379 R-DDI-5423647 https://reactome.org/PathwayBrowser/#/R-DDI-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Dictyostelium discoideum 15379 R-DDI-5661116 https://reactome.org/PathwayBrowser/#/R-DDI-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Dictyostelium discoideum 15379 R-DDI-5661121 https://reactome.org/PathwayBrowser/#/R-DDI-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Dictyostelium discoideum 15379 R-DDI-5662692 https://reactome.org/PathwayBrowser/#/R-DDI-5662692 Dopa is oxidized to dopaquinone by TYR IEA Dictyostelium discoideum 15379 R-DDI-5678327 https://reactome.org/PathwayBrowser/#/R-DDI-5678327 MIOX oxidises Ins to GlcA IEA Dictyostelium discoideum 15379 R-DDI-5690565 https://reactome.org/PathwayBrowser/#/R-DDI-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15379 R-DDI-5693681 https://reactome.org/PathwayBrowser/#/R-DDI-5693681 DUOX1,2 reduce O2 to H2O2 IEA Dictyostelium discoideum 15379 R-DDI-5693761 https://reactome.org/PathwayBrowser/#/R-DDI-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Dictyostelium discoideum 15379 R-DDI-5696119 https://reactome.org/PathwayBrowser/#/R-DDI-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Dictyostelium discoideum 15379 R-DDI-6783880 https://reactome.org/PathwayBrowser/#/R-DDI-6783880 PIPOX oxidises PPCA to P6C IEA Dictyostelium discoideum 15379 R-DDI-6787811 https://reactome.org/PathwayBrowser/#/R-DDI-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Dictyostelium discoideum 15379 R-DDI-6807557 https://reactome.org/PathwayBrowser/#/R-DDI-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Dictyostelium discoideum 15379 R-DDI-6810076 https://reactome.org/PathwayBrowser/#/R-DDI-6810076 DDO oxidizes D-Asp to OA IEA Dictyostelium discoideum 15379 R-DDI-6814153 https://reactome.org/PathwayBrowser/#/R-DDI-6814153 ADO oxidises 2AET to HTAU IEA Dictyostelium discoideum 15379 R-DDI-71118 https://reactome.org/PathwayBrowser/#/R-DDI-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Dictyostelium discoideum 15379 R-DDI-71163 https://reactome.org/PathwayBrowser/#/R-DDI-71163 HPD dioxygenates HPP IEA Dictyostelium discoideum 15379 R-DDI-71164 https://reactome.org/PathwayBrowser/#/R-DDI-71164 HGD dioxygenates homogentisate IEA Dictyostelium discoideum 15379 R-DDI-71188 https://reactome.org/PathwayBrowser/#/R-DDI-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Dictyostelium discoideum 15379 R-DDI-71200 https://reactome.org/PathwayBrowser/#/R-DDI-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Dictyostelium discoideum 15379 R-DDI-71218 https://reactome.org/PathwayBrowser/#/R-DDI-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Dictyostelium discoideum 15379 R-DDI-74247 https://reactome.org/PathwayBrowser/#/R-DDI-74247 XDH oxidizes hypoxanthine to form xanthine IEA Dictyostelium discoideum 15379 R-DDI-74258 https://reactome.org/PathwayBrowser/#/R-DDI-74258 XDH oxidizes xanthine to form urate IEA Dictyostelium discoideum 15379 R-DDI-76031 https://reactome.org/PathwayBrowser/#/R-DDI-76031 2 H2O2 => O2 + 2 H2O IEA Dictyostelium discoideum 15379 R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 15379 R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 15379 R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 15379 R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 15379 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 15379 R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 15379 R-DDI-8847579 https://reactome.org/PathwayBrowser/#/R-DDI-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15379 R-DDI-8865107 https://reactome.org/PathwayBrowser/#/R-DDI-8865107 MICAL1 produces NADP+, H2O2 IEA Dictyostelium discoideum 15379 R-DDI-8878581 https://reactome.org/PathwayBrowser/#/R-DDI-8878581 TYRP1 oxidises DHICA to IQCA IEA Dictyostelium discoideum 15379 R-DDI-8953398 https://reactome.org/PathwayBrowser/#/R-DDI-8953398 PIR oxygenates quercetin IEA Dictyostelium discoideum 15379 R-DDI-9018858 https://reactome.org/PathwayBrowser/#/R-DDI-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Dictyostelium discoideum 15379 R-DDI-9018859 https://reactome.org/PathwayBrowser/#/R-DDI-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Dictyostelium discoideum 15379 R-DDI-9018863 https://reactome.org/PathwayBrowser/#/R-DDI-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Dictyostelium discoideum 15379 R-DDI-9018894 https://reactome.org/PathwayBrowser/#/R-DDI-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Dictyostelium discoideum 15379 R-DDI-9018907 https://reactome.org/PathwayBrowser/#/R-DDI-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Dictyostelium discoideum 15379 R-DDI-9020251 https://reactome.org/PathwayBrowser/#/R-DDI-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Dictyostelium discoideum 15379 R-DDI-9020259 https://reactome.org/PathwayBrowser/#/R-DDI-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Dictyostelium discoideum 15379 R-DDI-9020264 https://reactome.org/PathwayBrowser/#/R-DDI-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Dictyostelium discoideum 15379 R-DDI-9020274 https://reactome.org/PathwayBrowser/#/R-DDI-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Dictyostelium discoideum 15379 R-DDI-9020275 https://reactome.org/PathwayBrowser/#/R-DDI-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Dictyostelium discoideum 15379 R-DDI-9020282 https://reactome.org/PathwayBrowser/#/R-DDI-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Dictyostelium discoideum 15379 R-DDI-9020610 https://reactome.org/PathwayBrowser/#/R-DDI-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Dictyostelium discoideum 15379 R-DDI-9024872 https://reactome.org/PathwayBrowser/#/R-DDI-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Dictyostelium discoideum 15379 R-DDI-9024997 https://reactome.org/PathwayBrowser/#/R-DDI-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Dictyostelium discoideum 15379 R-DDI-9025152 https://reactome.org/PathwayBrowser/#/R-DDI-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Dictyostelium discoideum 15379 R-DDI-9025957 https://reactome.org/PathwayBrowser/#/R-DDI-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Dictyostelium discoideum 15379 R-DDI-9025996 https://reactome.org/PathwayBrowser/#/R-DDI-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Dictyostelium discoideum 15379 R-DDI-9026003 https://reactome.org/PathwayBrowser/#/R-DDI-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Dictyostelium discoideum 15379 R-DDI-9026005 https://reactome.org/PathwayBrowser/#/R-DDI-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Dictyostelium discoideum 15379 R-DDI-9026006 https://reactome.org/PathwayBrowser/#/R-DDI-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Dictyostelium discoideum 15379 R-DDI-9026405 https://reactome.org/PathwayBrowser/#/R-DDI-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Dictyostelium discoideum 15379 R-DDI-9027043 https://reactome.org/PathwayBrowser/#/R-DDI-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Dictyostelium discoideum 15379 R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 15379 R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 15379 R-DDI-9027624 https://reactome.org/PathwayBrowser/#/R-DDI-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Dictyostelium discoideum 15379 R-DDI-9027628 https://reactome.org/PathwayBrowser/#/R-DDI-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Dictyostelium discoideum 15379 R-DDI-9027633 https://reactome.org/PathwayBrowser/#/R-DDI-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Dictyostelium discoideum 15379 R-DDI-9629578 https://reactome.org/PathwayBrowser/#/R-DDI-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Dictyostelium discoideum 15379 R-DDI-9629591 https://reactome.org/PathwayBrowser/#/R-DDI-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Dictyostelium discoideum 15379 R-DDI-9629869 https://reactome.org/PathwayBrowser/#/R-DDI-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Dictyostelium discoideum 15379 R-DDI-9630993 https://reactome.org/PathwayBrowser/#/R-DDI-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Dictyostelium discoideum 15379 R-DDI-965019 https://reactome.org/PathwayBrowser/#/R-DDI-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Dictyostelium discoideum 15379 R-DDI-965079 https://reactome.org/PathwayBrowser/#/R-DDI-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Dictyostelium discoideum 15379 R-DDI-9749986 https://reactome.org/PathwayBrowser/#/R-DDI-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Dictyostelium discoideum 15379 R-DDI-9750016 https://reactome.org/PathwayBrowser/#/R-DDI-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Dictyostelium discoideum 15379 R-DDI-9753285 https://reactome.org/PathwayBrowser/#/R-DDI-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Dictyostelium discoideum 15379 R-DDI-9817575 https://reactome.org/PathwayBrowser/#/R-DDI-9817575 ERO1B oxidizes P4HB IEA Dictyostelium discoideum 15379 R-DME-1234165 https://reactome.org/PathwayBrowser/#/R-DME-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 15379 R-DME-1234173 https://reactome.org/PathwayBrowser/#/R-DME-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 15379 R-DME-1234177 https://reactome.org/PathwayBrowser/#/R-DME-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 15379 R-DME-1234181 https://reactome.org/PathwayBrowser/#/R-DME-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 15379 R-DME-1237119 https://reactome.org/PathwayBrowser/#/R-DME-1237119 Acireductone is oxidized to MOB IEA Drosophila melanogaster 15379 R-DME-141341 https://reactome.org/PathwayBrowser/#/R-DME-141341 SMOX-3 oxidises SPN to SPM IEA Drosophila melanogaster 15379 R-DME-141348 https://reactome.org/PathwayBrowser/#/R-DME-141348 PAO:FAD oxidises NASPM to PTCN IEA Drosophila melanogaster 15379 R-DME-141351 https://reactome.org/PathwayBrowser/#/R-DME-141351 PAOX:FAD oxidises NASPN to SPM IEA Drosophila melanogaster 15379 R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 15379 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 15379 R-DME-1562626 https://reactome.org/PathwayBrowser/#/R-DME-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Drosophila melanogaster 15379 R-DME-156526 https://reactome.org/PathwayBrowser/#/R-DME-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Drosophila melanogaster 15379 R-DME-1614544 https://reactome.org/PathwayBrowser/#/R-DME-1614544 Sulfite is oxidized to sulfate IEA Drosophila melanogaster 15379 R-DME-1614605 https://reactome.org/PathwayBrowser/#/R-DME-1614605 Persulfide sulfur is dioxygenated IEA Drosophila melanogaster 15379 R-DME-1614645 https://reactome.org/PathwayBrowser/#/R-DME-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Drosophila melanogaster 15379 R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 15379 R-DME-189398 https://reactome.org/PathwayBrowser/#/R-DME-189398 HMOX1 dimer, HMOX2 cleave heme IEA Drosophila melanogaster 15379 R-DME-189421 https://reactome.org/PathwayBrowser/#/R-DME-189421 CPO transforms COPRO3 to PPGEN9 IEA Drosophila melanogaster 15379 R-DME-189423 https://reactome.org/PathwayBrowser/#/R-DME-189423 PPO oxidises PPGEN9 to PRIN9 IEA Drosophila melanogaster 15379 R-DME-192335 https://reactome.org/PathwayBrowser/#/R-DME-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Drosophila melanogaster 15379 R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 15379 R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 15379 R-DME-193369 https://reactome.org/PathwayBrowser/#/R-DME-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Drosophila melanogaster 15379 R-DME-1981104 https://reactome.org/PathwayBrowser/#/R-DME-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Drosophila melanogaster 15379 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 15379 R-DME-204662 https://reactome.org/PathwayBrowser/#/R-DME-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Drosophila melanogaster 15379 R-DME-2066787 https://reactome.org/PathwayBrowser/#/R-DME-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Drosophila melanogaster 15379 R-DME-209823 https://reactome.org/PathwayBrowser/#/R-DME-209823 Tyrosine is hydroxylated to dopa IEA Drosophila melanogaster 15379 R-DME-209828 https://reactome.org/PathwayBrowser/#/R-DME-209828 Tryptophan is hydroxylated IEA Drosophila melanogaster 15379 R-DME-209845 https://reactome.org/PathwayBrowser/#/R-DME-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Drosophila melanogaster 15379 R-DME-209891 https://reactome.org/PathwayBrowser/#/R-DME-209891 Dopamine is oxidised to noradrenaline IEA Drosophila melanogaster 15379 R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 15379 R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 15379 R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 15379 R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 15379 R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 15379 R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 15379 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 15379 R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 15379 R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 15379 R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 15379 R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 15379 R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 15379 R-DME-2161890 https://reactome.org/PathwayBrowser/#/R-DME-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Drosophila melanogaster 15379 R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Drosophila melanogaster 15379 R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 15379 R-DME-2172678 https://reactome.org/PathwayBrowser/#/R-DME-2172678 PHF8 demethylates histone H4K20me1 IEA Drosophila melanogaster 15379 R-DME-3204311 https://reactome.org/PathwayBrowser/#/R-DME-3204311 AOX1 oxidises PXL to PDXate IEA Drosophila melanogaster 15379 R-DME-3299680 https://reactome.org/PathwayBrowser/#/R-DME-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Drosophila melanogaster 15379 R-DME-3299691 https://reactome.org/PathwayBrowser/#/R-DME-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Drosophila melanogaster 15379 R-DME-3341294 https://reactome.org/PathwayBrowser/#/R-DME-3341294 Superoxide reduces cytochrome c IEA Drosophila melanogaster 15379 R-DME-3777112 https://reactome.org/PathwayBrowser/#/R-DME-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Drosophila melanogaster 15379 R-DME-389821 https://reactome.org/PathwayBrowser/#/R-DME-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Drosophila melanogaster 15379 R-DME-389842 https://reactome.org/PathwayBrowser/#/R-DME-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Drosophila melanogaster 15379 R-DME-389862 https://reactome.org/PathwayBrowser/#/R-DME-389862 Conversion of glyoxylate to oxalate IEA Drosophila melanogaster 15379 R-DME-389889 https://reactome.org/PathwayBrowser/#/R-DME-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Drosophila melanogaster 15379 R-DME-389891 https://reactome.org/PathwayBrowser/#/R-DME-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Drosophila melanogaster 15379 R-DME-390256 https://reactome.org/PathwayBrowser/#/R-DME-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Drosophila melanogaster 15379 R-DME-418436 https://reactome.org/PathwayBrowser/#/R-DME-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Drosophila melanogaster 15379 R-DME-428259 https://reactome.org/PathwayBrowser/#/R-DME-428259 DEGS1 dehydrogenates dihydroceramide IEA Drosophila melanogaster 15379 R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 15379 R-DME-5164399 https://reactome.org/PathwayBrowser/#/R-DME-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Drosophila melanogaster 15379 R-DME-5423647 https://reactome.org/PathwayBrowser/#/R-DME-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Drosophila melanogaster 15379 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 15379 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 15379 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 15379 R-DME-5661124 https://reactome.org/PathwayBrowser/#/R-DME-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Drosophila melanogaster 15379 R-DME-5661125 https://reactome.org/PathwayBrowser/#/R-DME-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Drosophila melanogaster 15379 R-DME-5678327 https://reactome.org/PathwayBrowser/#/R-DME-5678327 MIOX oxidises Ins to GlcA IEA Drosophila melanogaster 15379 R-DME-5690565 https://reactome.org/PathwayBrowser/#/R-DME-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15379 R-DME-5691107 https://reactome.org/PathwayBrowser/#/R-DME-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Drosophila melanogaster 15379 R-DME-5693681 https://reactome.org/PathwayBrowser/#/R-DME-5693681 DUOX1,2 reduce O2 to H2O2 IEA Drosophila melanogaster 15379 R-DME-5693761 https://reactome.org/PathwayBrowser/#/R-DME-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Drosophila melanogaster 15379 R-DME-6786239 https://reactome.org/PathwayBrowser/#/R-DME-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Drosophila melanogaster 15379 R-DME-6787811 https://reactome.org/PathwayBrowser/#/R-DME-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Drosophila melanogaster 15379 R-DME-6807557 https://reactome.org/PathwayBrowser/#/R-DME-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Drosophila melanogaster 15379 R-DME-6810076 https://reactome.org/PathwayBrowser/#/R-DME-6810076 DDO oxidizes D-Asp to OA IEA Drosophila melanogaster 15379 R-DME-6814153 https://reactome.org/PathwayBrowser/#/R-DME-6814153 ADO oxidises 2AET to HTAU IEA Drosophila melanogaster 15379 R-DME-71118 https://reactome.org/PathwayBrowser/#/R-DME-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Drosophila melanogaster 15379 R-DME-71163 https://reactome.org/PathwayBrowser/#/R-DME-71163 HPD dioxygenates HPP IEA Drosophila melanogaster 15379 R-DME-71164 https://reactome.org/PathwayBrowser/#/R-DME-71164 HGD dioxygenates homogentisate IEA Drosophila melanogaster 15379 R-DME-71188 https://reactome.org/PathwayBrowser/#/R-DME-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Drosophila melanogaster 15379 R-DME-71200 https://reactome.org/PathwayBrowser/#/R-DME-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Drosophila melanogaster 15379 R-DME-71241 https://reactome.org/PathwayBrowser/#/R-DME-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Drosophila melanogaster 15379 R-DME-71261 https://reactome.org/PathwayBrowser/#/R-DME-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Drosophila melanogaster 15379 R-DME-74247 https://reactome.org/PathwayBrowser/#/R-DME-74247 XDH oxidizes hypoxanthine to form xanthine IEA Drosophila melanogaster 15379 R-DME-74258 https://reactome.org/PathwayBrowser/#/R-DME-74258 XDH oxidizes xanthine to form urate IEA Drosophila melanogaster 15379 R-DME-76031 https://reactome.org/PathwayBrowser/#/R-DME-76031 2 H2O2 => O2 + 2 H2O IEA Drosophila melanogaster 15379 R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 15379 R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 15379 R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 15379 R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 15379 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 15379 R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 15379 R-DME-8847579 https://reactome.org/PathwayBrowser/#/R-DME-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15379 R-DME-9027043 https://reactome.org/PathwayBrowser/#/R-DME-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Drosophila melanogaster 15379 R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 15379 R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 15379 R-DME-9629578 https://reactome.org/PathwayBrowser/#/R-DME-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Drosophila melanogaster 15379 R-DME-9629591 https://reactome.org/PathwayBrowser/#/R-DME-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Drosophila melanogaster 15379 R-DME-9629869 https://reactome.org/PathwayBrowser/#/R-DME-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Drosophila melanogaster 15379 R-DME-9629888 https://reactome.org/PathwayBrowser/#/R-DME-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Drosophila melanogaster 15379 R-DME-9629946 https://reactome.org/PathwayBrowser/#/R-DME-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Drosophila melanogaster 15379 R-DME-9630022 https://reactome.org/PathwayBrowser/#/R-DME-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Drosophila melanogaster 15379 R-DME-9630769 https://reactome.org/PathwayBrowser/#/R-DME-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Drosophila melanogaster 15379 R-DME-9630993 https://reactome.org/PathwayBrowser/#/R-DME-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Drosophila melanogaster 15379 R-DME-965019 https://reactome.org/PathwayBrowser/#/R-DME-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Drosophila melanogaster 15379 R-DME-965079 https://reactome.org/PathwayBrowser/#/R-DME-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Drosophila melanogaster 15379 R-DME-9749986 https://reactome.org/PathwayBrowser/#/R-DME-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Drosophila melanogaster 15379 R-DME-9750016 https://reactome.org/PathwayBrowser/#/R-DME-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Drosophila melanogaster 15379 R-DME-9753285 https://reactome.org/PathwayBrowser/#/R-DME-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Drosophila melanogaster 15379 R-DME-975635 https://reactome.org/PathwayBrowser/#/R-DME-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Drosophila melanogaster 15379 R-DME-9817575 https://reactome.org/PathwayBrowser/#/R-DME-9817575 ERO1B oxidizes P4HB IEA Drosophila melanogaster 15379 R-DRE-1222376 https://reactome.org/PathwayBrowser/#/R-DRE-1222376 NOX2 generates superoxide from oxygen IEA Danio rerio 15379 R-DRE-1234164 https://reactome.org/PathwayBrowser/#/R-DRE-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Danio rerio 15379 R-DRE-1234165 https://reactome.org/PathwayBrowser/#/R-DRE-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Danio rerio 15379 R-DRE-1234181 https://reactome.org/PathwayBrowser/#/R-DRE-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Danio rerio 15379 R-DRE-1236967 https://reactome.org/PathwayBrowser/#/R-DRE-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Danio rerio 15379 R-DRE-1237119 https://reactome.org/PathwayBrowser/#/R-DRE-1237119 Acireductone is oxidized to MOB IEA Danio rerio 15379 R-DRE-1237325 https://reactome.org/PathwayBrowser/#/R-DRE-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Danio rerio 15379 R-DRE-1247668 https://reactome.org/PathwayBrowser/#/R-DRE-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Danio rerio 15379 R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 15379 R-DRE-140355 https://reactome.org/PathwayBrowser/#/R-DRE-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Danio rerio 15379 R-DRE-141200 https://reactome.org/PathwayBrowser/#/R-DRE-141200 MAOB:FAD oxidatively deaminates of PEA IEA Danio rerio 15379 R-DRE-141202 https://reactome.org/PathwayBrowser/#/R-DRE-141202 MAOB:FAD oxidatively deaminates TYR IEA Danio rerio 15379 R-DRE-141348 https://reactome.org/PathwayBrowser/#/R-DRE-141348 PAO:FAD oxidises NASPM to PTCN IEA Danio rerio 15379 R-DRE-141351 https://reactome.org/PathwayBrowser/#/R-DRE-141351 PAOX:FAD oxidises NASPN to SPM IEA Danio rerio 15379 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 15379 R-DRE-1562626 https://reactome.org/PathwayBrowser/#/R-DRE-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Danio rerio 15379 R-DRE-156526 https://reactome.org/PathwayBrowser/#/R-DRE-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Danio rerio 15379 R-DRE-1614605 https://reactome.org/PathwayBrowser/#/R-DRE-1614605 Persulfide sulfur is dioxygenated IEA Danio rerio 15379 R-DRE-1614645 https://reactome.org/PathwayBrowser/#/R-DRE-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Danio rerio 15379 R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 15379 R-DRE-1650808 https://reactome.org/PathwayBrowser/#/R-DRE-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Danio rerio 15379 R-DRE-1655453 https://reactome.org/PathwayBrowser/#/R-DRE-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Danio rerio 15379 R-DRE-189398 https://reactome.org/PathwayBrowser/#/R-DRE-189398 HMOX1 dimer, HMOX2 cleave heme IEA Danio rerio 15379 R-DRE-189421 https://reactome.org/PathwayBrowser/#/R-DRE-189421 CPO transforms COPRO3 to PPGEN9 IEA Danio rerio 15379 R-DRE-189423 https://reactome.org/PathwayBrowser/#/R-DRE-189423 PPO oxidises PPGEN9 to PRIN9 IEA Danio rerio 15379 R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 15379 R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 15379 R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 15379 R-DRE-192157 https://reactome.org/PathwayBrowser/#/R-DRE-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Danio rerio 15379 R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 15379 R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 15379 R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 15379 R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 15379 R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 15379 R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 15379 R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 15379 R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 15379 R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 15379 R-DRE-193709 https://reactome.org/PathwayBrowser/#/R-DRE-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Danio rerio 15379 R-DRE-193845 https://reactome.org/PathwayBrowser/#/R-DRE-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Danio rerio 15379 R-DRE-194641 https://reactome.org/PathwayBrowser/#/R-DRE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15379 R-DRE-194669 https://reactome.org/PathwayBrowser/#/R-DRE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15379 R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 15379 R-DRE-195664 https://reactome.org/PathwayBrowser/#/R-DRE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Danio rerio 15379 R-DRE-1981104 https://reactome.org/PathwayBrowser/#/R-DRE-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Danio rerio 15379 R-DRE-2002466 https://reactome.org/PathwayBrowser/#/R-DRE-2002466 Formation of allysine by LOX IEA Danio rerio 15379 R-DRE-2046084 https://reactome.org/PathwayBrowser/#/R-DRE-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Danio rerio 15379 R-DRE-2046096 https://reactome.org/PathwayBrowser/#/R-DRE-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Danio rerio 15379 R-DRE-2046097 https://reactome.org/PathwayBrowser/#/R-DRE-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 15379 R-DRE-204662 https://reactome.org/PathwayBrowser/#/R-DRE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Danio rerio 15379 R-DRE-2066787 https://reactome.org/PathwayBrowser/#/R-DRE-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Danio rerio 15379 R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 15379 R-DRE-209823 https://reactome.org/PathwayBrowser/#/R-DRE-209823 Tyrosine is hydroxylated to dopa IEA Danio rerio 15379 R-DRE-209828 https://reactome.org/PathwayBrowser/#/R-DRE-209828 Tryptophan is hydroxylated IEA Danio rerio 15379 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 15379 R-DRE-209891 https://reactome.org/PathwayBrowser/#/R-DRE-209891 Dopamine is oxidised to noradrenaline IEA Danio rerio 15379 R-DRE-211873 https://reactome.org/PathwayBrowser/#/R-DRE-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Danio rerio 15379 R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 15379 R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 15379 R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 15379 R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 15379 R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 15379 R-DRE-211923 https://reactome.org/PathwayBrowser/#/R-DRE-211923 CYP26C1 4-hydroxylates 9cRA IEA Danio rerio 15379 R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 15379 R-DRE-211950 https://reactome.org/PathwayBrowser/#/R-DRE-211950 CYP24A1 24-hydroxylates CTL IEA Danio rerio 15379 R-DRE-211951 https://reactome.org/PathwayBrowser/#/R-DRE-211951 CYP1B1 4-hydroxylates EST17b IEA Danio rerio 15379 R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 15379 R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 15379 R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 15379 R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 15379 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 15379 R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 15379 R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 15379 R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 15379 R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 15379 R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 15379 R-DRE-2161745 https://reactome.org/PathwayBrowser/#/R-DRE-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Danio rerio 15379 R-DRE-2161775 https://reactome.org/PathwayBrowser/#/R-DRE-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Danio rerio 15379 R-DRE-2161792 https://reactome.org/PathwayBrowser/#/R-DRE-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Danio rerio 15379 R-DRE-2161794 https://reactome.org/PathwayBrowser/#/R-DRE-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Danio rerio 15379 R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Danio rerio 15379 R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 15379 R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio 15379 R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Danio rerio 15379 R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 15379 R-DRE-2161950 https://reactome.org/PathwayBrowser/#/R-DRE-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Danio rerio 15379 R-DRE-2161951 https://reactome.org/PathwayBrowser/#/R-DRE-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Danio rerio 15379 R-DRE-2161964 https://reactome.org/PathwayBrowser/#/R-DRE-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Danio rerio 15379 R-DRE-2162002 https://reactome.org/PathwayBrowser/#/R-DRE-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Danio rerio 15379 R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 15379 R-DRE-2168885 https://reactome.org/PathwayBrowser/#/R-DRE-2168885 Haptoglobin binds Hemoglobin IEA Danio rerio 15379 R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 15379 R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 15379 R-DRE-2172678 https://reactome.org/PathwayBrowser/#/R-DRE-2172678 PHF8 demethylates histone H4K20me1 IEA Danio rerio 15379 R-DRE-2230938 https://reactome.org/PathwayBrowser/#/R-DRE-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Danio rerio 15379 R-DRE-2309787 https://reactome.org/PathwayBrowser/#/R-DRE-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Danio rerio 15379 R-DRE-2395340 https://reactome.org/PathwayBrowser/#/R-DRE-2395340 Formation of hydroxyallysine by LOX IEA Danio rerio 15379 R-DRE-3204311 https://reactome.org/PathwayBrowser/#/R-DRE-3204311 AOX1 oxidises PXL to PDXate IEA Danio rerio 15379 R-DRE-3299680 https://reactome.org/PathwayBrowser/#/R-DRE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Danio rerio 15379 R-DRE-3299682 https://reactome.org/PathwayBrowser/#/R-DRE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Danio rerio 15379 R-DRE-3299691 https://reactome.org/PathwayBrowser/#/R-DRE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Danio rerio 15379 R-DRE-3341294 https://reactome.org/PathwayBrowser/#/R-DRE-3341294 Superoxide reduces cytochrome c IEA Danio rerio 15379 R-DRE-3777112 https://reactome.org/PathwayBrowser/#/R-DRE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Danio rerio 15379 R-DRE-389639 https://reactome.org/PathwayBrowser/#/R-DRE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Danio rerio 15379 R-DRE-389821 https://reactome.org/PathwayBrowser/#/R-DRE-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Danio rerio 15379 R-DRE-389842 https://reactome.org/PathwayBrowser/#/R-DRE-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Danio rerio 15379 R-DRE-389862 https://reactome.org/PathwayBrowser/#/R-DRE-389862 Conversion of glyoxylate to oxalate IEA Danio rerio 15379 R-DRE-389891 https://reactome.org/PathwayBrowser/#/R-DRE-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Danio rerio 15379 R-DRE-390256 https://reactome.org/PathwayBrowser/#/R-DRE-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Danio rerio 15379 R-DRE-418436 https://reactome.org/PathwayBrowser/#/R-DRE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Danio rerio 15379 R-DRE-428259 https://reactome.org/PathwayBrowser/#/R-DRE-428259 DEGS1 dehydrogenates dihydroceramide IEA Danio rerio 15379 R-DRE-5164399 https://reactome.org/PathwayBrowser/#/R-DRE-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Danio rerio 15379 R-DRE-5218841 https://reactome.org/PathwayBrowser/#/R-DRE-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Danio rerio 15379 R-DRE-5340214 https://reactome.org/PathwayBrowser/#/R-DRE-5340214 CYGB binds O2 IEA Danio rerio 15379 R-DRE-5340226 https://reactome.org/PathwayBrowser/#/R-DRE-5340226 CYGB dioxygenates NO IEA Danio rerio 15379 R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 15379 R-DRE-5423117 https://reactome.org/PathwayBrowser/#/R-DRE-5423117 PHF8 demethylates MeK21-histone H4 IEA Danio rerio 15379 R-DRE-5423647 https://reactome.org/PathwayBrowser/#/R-DRE-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Danio rerio 15379 R-DRE-5423664 https://reactome.org/PathwayBrowser/#/R-DRE-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Danio rerio 15379 R-DRE-5423672 https://reactome.org/PathwayBrowser/#/R-DRE-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Danio rerio 15379 R-DRE-5423678 https://reactome.org/PathwayBrowser/#/R-DRE-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Danio rerio 15379 R-DRE-5602295 https://reactome.org/PathwayBrowser/#/R-DRE-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Danio rerio 15379 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 15379 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 15379 R-DRE-5661124 https://reactome.org/PathwayBrowser/#/R-DRE-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Danio rerio 15379 R-DRE-5661125 https://reactome.org/PathwayBrowser/#/R-DRE-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Danio rerio 15379 R-DRE-5668629 https://reactome.org/PathwayBrowser/#/R-DRE-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Danio rerio 15379 R-DRE-5668718 https://reactome.org/PathwayBrowser/#/R-DRE-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 15379 R-DRE-5668731 https://reactome.org/PathwayBrowser/#/R-DRE-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 15379 R-DRE-5678327 https://reactome.org/PathwayBrowser/#/R-DRE-5678327 MIOX oxidises Ins to GlcA IEA Danio rerio 15379 R-DRE-5690565 https://reactome.org/PathwayBrowser/#/R-DRE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Danio rerio 15379 R-DRE-5691107 https://reactome.org/PathwayBrowser/#/R-DRE-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Danio rerio 15379 R-DRE-5696119 https://reactome.org/PathwayBrowser/#/R-DRE-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Danio rerio 15379 R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 15379 R-DRE-6786239 https://reactome.org/PathwayBrowser/#/R-DRE-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Danio rerio 15379 R-DRE-6789092 https://reactome.org/PathwayBrowser/#/R-DRE-6789092 NOX2 generates superoxide anion from oxygen IEA Danio rerio 15379 R-DRE-6807053 https://reactome.org/PathwayBrowser/#/R-DRE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Danio rerio 15379 R-DRE-6814153 https://reactome.org/PathwayBrowser/#/R-DRE-6814153 ADO oxidises 2AET to HTAU IEA Danio rerio 15379 R-DRE-71118 https://reactome.org/PathwayBrowser/#/R-DRE-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Danio rerio 15379 R-DRE-71163 https://reactome.org/PathwayBrowser/#/R-DRE-71163 HPD dioxygenates HPP IEA Danio rerio 15379 R-DRE-71164 https://reactome.org/PathwayBrowser/#/R-DRE-71164 HGD dioxygenates homogentisate IEA Danio rerio 15379 R-DRE-71188 https://reactome.org/PathwayBrowser/#/R-DRE-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Danio rerio 15379 R-DRE-71200 https://reactome.org/PathwayBrowser/#/R-DRE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Danio rerio 15379 R-DRE-71218 https://reactome.org/PathwayBrowser/#/R-DRE-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Danio rerio 15379 R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio 15379 R-DRE-76031 https://reactome.org/PathwayBrowser/#/R-DRE-76031 2 H2O2 => O2 + 2 H2O IEA Danio rerio 15379 R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 15379 R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 15379 R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 15379 R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 15379 R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 15379 R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 15379 R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 15379 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 15379 R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 15379 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 15379 R-DRE-8865107 https://reactome.org/PathwayBrowser/#/R-DRE-8865107 MICAL1 produces NADP+, H2O2 IEA Danio rerio 15379 R-DRE-8878581 https://reactome.org/PathwayBrowser/#/R-DRE-8878581 TYRP1 oxidises DHICA to IQCA IEA Danio rerio 15379 R-DRE-888614 https://reactome.org/PathwayBrowser/#/R-DRE-888614 IDO2 dioxygenates L-Trp to NFK IEA Danio rerio 15379 R-DRE-8956458 https://reactome.org/PathwayBrowser/#/R-DRE-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Danio rerio 15379 R-DRE-8981606 https://reactome.org/PathwayBrowser/#/R-DRE-8981606 Myoglobin binds oxygen IEA Danio rerio 15379 R-DRE-8981610 https://reactome.org/PathwayBrowser/#/R-DRE-8981610 Neuroglobin binds oxygen IEA Danio rerio 15379 R-DRE-8981621 https://reactome.org/PathwayBrowser/#/R-DRE-8981621 Neuroglobin:oxygen dissociates IEA Danio rerio 15379 R-DRE-8981622 https://reactome.org/PathwayBrowser/#/R-DRE-8981622 Myoglobin:oxygen dissociates IEA Danio rerio 15379 R-DRE-8982617 https://reactome.org/PathwayBrowser/#/R-DRE-8982617 CYGB:O2 dissociates IEA Danio rerio 15379 R-DRE-9018858 https://reactome.org/PathwayBrowser/#/R-DRE-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Danio rerio 15379 R-DRE-9018859 https://reactome.org/PathwayBrowser/#/R-DRE-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Danio rerio 15379 R-DRE-9018863 https://reactome.org/PathwayBrowser/#/R-DRE-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Danio rerio 15379 R-DRE-9018880 https://reactome.org/PathwayBrowser/#/R-DRE-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Danio rerio 15379 R-DRE-9018894 https://reactome.org/PathwayBrowser/#/R-DRE-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Danio rerio 15379 R-DRE-9018907 https://reactome.org/PathwayBrowser/#/R-DRE-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Danio rerio 15379 R-DRE-9020251 https://reactome.org/PathwayBrowser/#/R-DRE-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Danio rerio 15379 R-DRE-9020259 https://reactome.org/PathwayBrowser/#/R-DRE-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Danio rerio 15379 R-DRE-9020261 https://reactome.org/PathwayBrowser/#/R-DRE-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Danio rerio 15379 R-DRE-9020264 https://reactome.org/PathwayBrowser/#/R-DRE-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Danio rerio 15379 R-DRE-9020274 https://reactome.org/PathwayBrowser/#/R-DRE-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Danio rerio 15379 R-DRE-9020275 https://reactome.org/PathwayBrowser/#/R-DRE-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Danio rerio 15379 R-DRE-9020282 https://reactome.org/PathwayBrowser/#/R-DRE-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Danio rerio 15379 R-DRE-9020610 https://reactome.org/PathwayBrowser/#/R-DRE-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Danio rerio 15379 R-DRE-9024872 https://reactome.org/PathwayBrowser/#/R-DRE-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Danio rerio 15379 R-DRE-9024997 https://reactome.org/PathwayBrowser/#/R-DRE-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Danio rerio 15379 R-DRE-9025152 https://reactome.org/PathwayBrowser/#/R-DRE-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Danio rerio 15379 R-DRE-9025957 https://reactome.org/PathwayBrowser/#/R-DRE-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Danio rerio 15379 R-DRE-9025996 https://reactome.org/PathwayBrowser/#/R-DRE-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Danio rerio 15379 R-DRE-9026003 https://reactome.org/PathwayBrowser/#/R-DRE-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Danio rerio 15379 R-DRE-9026005 https://reactome.org/PathwayBrowser/#/R-DRE-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Danio rerio 15379 R-DRE-9026006 https://reactome.org/PathwayBrowser/#/R-DRE-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Danio rerio 15379 R-DRE-9026405 https://reactome.org/PathwayBrowser/#/R-DRE-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Danio rerio 15379 R-DRE-9026408 https://reactome.org/PathwayBrowser/#/R-DRE-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Danio rerio 15379 R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio 15379 R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 15379 R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 15379 R-DRE-9027532 https://reactome.org/PathwayBrowser/#/R-DRE-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Danio rerio 15379 R-DRE-9027607 https://reactome.org/PathwayBrowser/#/R-DRE-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Danio rerio 15379 R-DRE-9027624 https://reactome.org/PathwayBrowser/#/R-DRE-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Danio rerio 15379 R-DRE-9027627 https://reactome.org/PathwayBrowser/#/R-DRE-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Danio rerio 15379 R-DRE-9027628 https://reactome.org/PathwayBrowser/#/R-DRE-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Danio rerio 15379 R-DRE-9027633 https://reactome.org/PathwayBrowser/#/R-DRE-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Danio rerio 15379 R-DRE-9028255 https://reactome.org/PathwayBrowser/#/R-DRE-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Danio rerio 15379 R-DRE-9037761 https://reactome.org/PathwayBrowser/#/R-DRE-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Danio rerio 15379 R-DRE-917891 https://reactome.org/PathwayBrowser/#/R-DRE-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Danio rerio 15379 R-DRE-9629591 https://reactome.org/PathwayBrowser/#/R-DRE-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Danio rerio 15379 R-DRE-9629869 https://reactome.org/PathwayBrowser/#/R-DRE-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Danio rerio 15379 R-DRE-9629946 https://reactome.org/PathwayBrowser/#/R-DRE-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Danio rerio 15379 R-DRE-9630993 https://reactome.org/PathwayBrowser/#/R-DRE-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Danio rerio 15379 R-DRE-9709360 https://reactome.org/PathwayBrowser/#/R-DRE-9709360 H2O2 reduces MetHb IEA Danio rerio 15379 R-DRE-9749986 https://reactome.org/PathwayBrowser/#/R-DRE-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Danio rerio 15379 R-DRE-9750016 https://reactome.org/PathwayBrowser/#/R-DRE-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Danio rerio 15379 R-DRE-9753285 https://reactome.org/PathwayBrowser/#/R-DRE-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Danio rerio 15379 R-DRE-9756138 https://reactome.org/PathwayBrowser/#/R-DRE-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Danio rerio 15379 R-DRE-9756162 https://reactome.org/PathwayBrowser/#/R-DRE-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Danio rerio 15379 R-DRE-9756169 https://reactome.org/PathwayBrowser/#/R-DRE-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Danio rerio 15379 R-DRE-9756180 https://reactome.org/PathwayBrowser/#/R-DRE-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Danio rerio 15379 R-DRE-975635 https://reactome.org/PathwayBrowser/#/R-DRE-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Danio rerio 15379 R-DRE-9758674 https://reactome.org/PathwayBrowser/#/R-DRE-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Danio rerio 15379 R-GGA-1222376 https://reactome.org/PathwayBrowser/#/R-GGA-1222376 NOX2 generates superoxide from oxygen IEA Gallus gallus 15379 R-GGA-1234164 https://reactome.org/PathwayBrowser/#/R-GGA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Gallus gallus 15379 R-GGA-1234165 https://reactome.org/PathwayBrowser/#/R-GGA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 15379 R-GGA-1234173 https://reactome.org/PathwayBrowser/#/R-GGA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 15379 R-GGA-1234177 https://reactome.org/PathwayBrowser/#/R-GGA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 15379 R-GGA-1234181 https://reactome.org/PathwayBrowser/#/R-GGA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 15379 R-GGA-1236967 https://reactome.org/PathwayBrowser/#/R-GGA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Gallus gallus 15379 R-GGA-1237119 https://reactome.org/PathwayBrowser/#/R-GGA-1237119 Acireductone is oxidized to MOB IEA Gallus gallus 15379 R-GGA-1237325 https://reactome.org/PathwayBrowser/#/R-GGA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Gallus gallus 15379 R-GGA-1247668 https://reactome.org/PathwayBrowser/#/R-GGA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Gallus gallus 15379 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 15379 R-GGA-140355 https://reactome.org/PathwayBrowser/#/R-GGA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Gallus gallus 15379 R-GGA-141186 https://reactome.org/PathwayBrowser/#/R-GGA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Gallus gallus 15379 R-GGA-141200 https://reactome.org/PathwayBrowser/#/R-GGA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Gallus gallus 15379 R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus 15379 R-GGA-141341 https://reactome.org/PathwayBrowser/#/R-GGA-141341 SMOX-3 oxidises SPN to SPM IEA Gallus gallus 15379 R-GGA-141348 https://reactome.org/PathwayBrowser/#/R-GGA-141348 PAO:FAD oxidises NASPM to PTCN IEA Gallus gallus 15379 R-GGA-141351 https://reactome.org/PathwayBrowser/#/R-GGA-141351 PAOX:FAD oxidises NASPN to SPM IEA Gallus gallus 15379 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 15379 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 15379 R-GGA-1562626 https://reactome.org/PathwayBrowser/#/R-GGA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Gallus gallus 15379 R-GGA-156526 https://reactome.org/PathwayBrowser/#/R-GGA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Gallus gallus 15379 R-GGA-1614544 https://reactome.org/PathwayBrowser/#/R-GGA-1614544 Sulfite is oxidized to sulfate IEA Gallus gallus 15379 R-GGA-1614645 https://reactome.org/PathwayBrowser/#/R-GGA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Gallus gallus 15379 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 15379 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus 15379 R-GGA-189398 https://reactome.org/PathwayBrowser/#/R-GGA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Gallus gallus 15379 R-GGA-189421 https://reactome.org/PathwayBrowser/#/R-GGA-189421 CPO transforms COPRO3 to PPGEN9 IEA Gallus gallus 15379 R-GGA-189423 https://reactome.org/PathwayBrowser/#/R-GGA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Gallus gallus 15379 R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 15379 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 15379 R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 15379 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 15379 R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 15379 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 15379 R-GGA-192178 https://reactome.org/PathwayBrowser/#/R-GGA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Gallus gallus 15379 R-GGA-192335 https://reactome.org/PathwayBrowser/#/R-GGA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Gallus gallus 15379 R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 15379 R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 15379 R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 15379 R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 15379 R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 15379 R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 15379 R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 15379 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 15379 R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 15379 R-GGA-193369 https://reactome.org/PathwayBrowser/#/R-GGA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Gallus gallus 15379 R-GGA-193964 https://reactome.org/PathwayBrowser/#/R-GGA-193964 CYP21A2 21-hydroxylates PROG IEA Gallus gallus 15379 R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 15379 R-GGA-194641 https://reactome.org/PathwayBrowser/#/R-GGA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15379 R-GGA-194669 https://reactome.org/PathwayBrowser/#/R-GGA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15379 R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 15379 R-GGA-195664 https://reactome.org/PathwayBrowser/#/R-GGA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Gallus gallus 15379 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus 15379 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus 15379 R-GGA-2002466 https://reactome.org/PathwayBrowser/#/R-GGA-2002466 Formation of allysine by LOX IEA Gallus gallus 15379 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 15379 R-GGA-2046084 https://reactome.org/PathwayBrowser/#/R-GGA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Gallus gallus 15379 R-GGA-2046089 https://reactome.org/PathwayBrowser/#/R-GGA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Gallus gallus 15379 R-GGA-2046092 https://reactome.org/PathwayBrowser/#/R-GGA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Gallus gallus 15379 R-GGA-2046096 https://reactome.org/PathwayBrowser/#/R-GGA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Gallus gallus 15379 R-GGA-2046097 https://reactome.org/PathwayBrowser/#/R-GGA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 15379 R-GGA-204662 https://reactome.org/PathwayBrowser/#/R-GGA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Gallus gallus 15379 R-GGA-2066787 https://reactome.org/PathwayBrowser/#/R-GGA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Gallus gallus 15379 R-GGA-209823 https://reactome.org/PathwayBrowser/#/R-GGA-209823 Tyrosine is hydroxylated to dopa IEA Gallus gallus 15379 R-GGA-209828 https://reactome.org/PathwayBrowser/#/R-GGA-209828 Tryptophan is hydroxylated IEA Gallus gallus 15379 R-GGA-209845 https://reactome.org/PathwayBrowser/#/R-GGA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Gallus gallus 15379 R-GGA-209891 https://reactome.org/PathwayBrowser/#/R-GGA-209891 Dopamine is oxidised to noradrenaline IEA Gallus gallus 15379 R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 15379 R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 15379 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 15379 R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus 15379 R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 15379 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 15379 R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 15379 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 15379 R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 15379 R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 15379 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 15379 R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 15379 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 15379 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 15379 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 15379 R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 15379 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 15379 R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 15379 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Gallus gallus 15379 R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 15379 R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus 15379 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Gallus gallus 15379 R-GGA-2161907 https://reactome.org/PathwayBrowser/#/R-GGA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Gallus gallus 15379 R-GGA-2161917 https://reactome.org/PathwayBrowser/#/R-GGA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Gallus gallus 15379 R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 15379 R-GGA-2161950 https://reactome.org/PathwayBrowser/#/R-GGA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Gallus gallus 15379 R-GGA-2161951 https://reactome.org/PathwayBrowser/#/R-GGA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Gallus gallus 15379 R-GGA-2162002 https://reactome.org/PathwayBrowser/#/R-GGA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Gallus gallus 15379 R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 15379 R-GGA-2168885 https://reactome.org/PathwayBrowser/#/R-GGA-2168885 Haptoglobin binds Hemoglobin IEA Gallus gallus 15379 R-GGA-2172678 https://reactome.org/PathwayBrowser/#/R-GGA-2172678 PHF8 demethylates histone H4K20me1 IEA Gallus gallus 15379 R-GGA-2230938 https://reactome.org/PathwayBrowser/#/R-GGA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Gallus gallus 15379 R-GGA-2309787 https://reactome.org/PathwayBrowser/#/R-GGA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Gallus gallus 15379 R-GGA-2395340 https://reactome.org/PathwayBrowser/#/R-GGA-2395340 Formation of hydroxyallysine by LOX IEA Gallus gallus 15379 R-GGA-265296 https://reactome.org/PathwayBrowser/#/R-GGA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Gallus gallus 15379 R-GGA-3204311 https://reactome.org/PathwayBrowser/#/R-GGA-3204311 AOX1 oxidises PXL to PDXate IEA Gallus gallus 15379 R-GGA-3299680 https://reactome.org/PathwayBrowser/#/R-GGA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Gallus gallus 15379 R-GGA-3299682 https://reactome.org/PathwayBrowser/#/R-GGA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Gallus gallus 15379 R-GGA-3299691 https://reactome.org/PathwayBrowser/#/R-GGA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Gallus gallus 15379 R-GGA-3341294 https://reactome.org/PathwayBrowser/#/R-GGA-3341294 Superoxide reduces cytochrome c IEA Gallus gallus 15379 R-GGA-353356 https://reactome.org/PathwayBrowser/#/R-GGA-353356 Reversal of Alkylation Damage By DNA Dioxygenases TAS Gallus gallus 15379 R-GGA-374909 https://reactome.org/PathwayBrowser/#/R-GGA-374909 Catabolism of Noradrenaline IEA Gallus gallus 15379 R-GGA-3777112 https://reactome.org/PathwayBrowser/#/R-GGA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Gallus gallus 15379 R-GGA-379382 https://reactome.org/PathwayBrowser/#/R-GGA-379382 MAOA:FAD deaminates DA to DOPAC IEA Gallus gallus 15379 R-GGA-379395 https://reactome.org/PathwayBrowser/#/R-GGA-379395 MAOA:FAD deaminates 3MT to HVA IEA Gallus gallus 15379 R-GGA-389639 https://reactome.org/PathwayBrowser/#/R-GGA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Gallus gallus 15379 R-GGA-389821 https://reactome.org/PathwayBrowser/#/R-GGA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Gallus gallus 15379 R-GGA-389842 https://reactome.org/PathwayBrowser/#/R-GGA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Gallus gallus 15379 R-GGA-389862 https://reactome.org/PathwayBrowser/#/R-GGA-389862 Conversion of glyoxylate to oxalate IEA Gallus gallus 15379 R-GGA-389889 https://reactome.org/PathwayBrowser/#/R-GGA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Gallus gallus 15379 R-GGA-389891 https://reactome.org/PathwayBrowser/#/R-GGA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Gallus gallus 15379 R-GGA-390256 https://reactome.org/PathwayBrowser/#/R-GGA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Gallus gallus 15379 R-GGA-418436 https://reactome.org/PathwayBrowser/#/R-GGA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Gallus gallus 15379 R-GGA-421452 https://reactome.org/PathwayBrowser/#/R-GGA-421452 2 protoporphyrinogen IX + 3 O2 => 2 protoporphyrin IX + 6 H2O IEA Gallus gallus 15379 R-GGA-421478 https://reactome.org/PathwayBrowser/#/R-GGA-421478 coproporphyrinogen III + 2 O2 => protoporphyrinogen IX + 2 H2O2 + 2 CO2 IEA Gallus gallus 15379 R-GGA-428259 https://reactome.org/PathwayBrowser/#/R-GGA-428259 DEGS1 dehydrogenates dihydroceramide IEA Gallus gallus 15379 R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 15379 R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 15379 R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 15379 R-GGA-5164399 https://reactome.org/PathwayBrowser/#/R-GGA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Gallus gallus 15379 R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus 15379 R-GGA-5340214 https://reactome.org/PathwayBrowser/#/R-GGA-5340214 CYGB binds O2 IEA Gallus gallus 15379 R-GGA-5340226 https://reactome.org/PathwayBrowser/#/R-GGA-5340226 CYGB dioxygenates NO IEA Gallus gallus 15379 R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 15379 R-GGA-5423664 https://reactome.org/PathwayBrowser/#/R-GGA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Gallus gallus 15379 R-GGA-5423672 https://reactome.org/PathwayBrowser/#/R-GGA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Gallus gallus 15379 R-GGA-5423678 https://reactome.org/PathwayBrowser/#/R-GGA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Gallus gallus 15379 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 15379 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 15379 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 15379 R-GGA-5661124 https://reactome.org/PathwayBrowser/#/R-GGA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Gallus gallus 15379 R-GGA-5661125 https://reactome.org/PathwayBrowser/#/R-GGA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Gallus gallus 15379 R-GGA-5662692 https://reactome.org/PathwayBrowser/#/R-GGA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Gallus gallus 15379 R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus 15379 R-GGA-5668718 https://reactome.org/PathwayBrowser/#/R-GGA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 15379 R-GGA-5668731 https://reactome.org/PathwayBrowser/#/R-GGA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 15379 R-GGA-5678327 https://reactome.org/PathwayBrowser/#/R-GGA-5678327 MIOX oxidises Ins to GlcA IEA Gallus gallus 15379 R-GGA-5690565 https://reactome.org/PathwayBrowser/#/R-GGA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15379 R-GGA-5691107 https://reactome.org/PathwayBrowser/#/R-GGA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Gallus gallus 15379 R-GGA-5693681 https://reactome.org/PathwayBrowser/#/R-GGA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Gallus gallus 15379 R-GGA-5693761 https://reactome.org/PathwayBrowser/#/R-GGA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Gallus gallus 15379 R-GGA-5696119 https://reactome.org/PathwayBrowser/#/R-GGA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Gallus gallus 15379 R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 15379 R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 15379 R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 15379 R-GGA-6783880 https://reactome.org/PathwayBrowser/#/R-GGA-6783880 PIPOX oxidises PPCA to P6C IEA Gallus gallus 15379 R-GGA-6786239 https://reactome.org/PathwayBrowser/#/R-GGA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Gallus gallus 15379 R-GGA-6787811 https://reactome.org/PathwayBrowser/#/R-GGA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Gallus gallus 15379 R-GGA-6789092 https://reactome.org/PathwayBrowser/#/R-GGA-6789092 NOX2 generates superoxide anion from oxygen IEA Gallus gallus 15379 R-GGA-6807053 https://reactome.org/PathwayBrowser/#/R-GGA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Gallus gallus 15379 R-GGA-6807557 https://reactome.org/PathwayBrowser/#/R-GGA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Gallus gallus 15379 R-GGA-6810076 https://reactome.org/PathwayBrowser/#/R-GGA-6810076 DDO oxidizes D-Asp to OA IEA Gallus gallus 15379 R-GGA-71118 https://reactome.org/PathwayBrowser/#/R-GGA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Gallus gallus 15379 R-GGA-71163 https://reactome.org/PathwayBrowser/#/R-GGA-71163 HPD dioxygenates HPP IEA Gallus gallus 15379 R-GGA-71164 https://reactome.org/PathwayBrowser/#/R-GGA-71164 HGD dioxygenates homogentisate IEA Gallus gallus 15379 R-GGA-71188 https://reactome.org/PathwayBrowser/#/R-GGA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Gallus gallus 15379 R-GGA-71200 https://reactome.org/PathwayBrowser/#/R-GGA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Gallus gallus 15379 R-GGA-71218 https://reactome.org/PathwayBrowser/#/R-GGA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Gallus gallus 15379 R-GGA-71241 https://reactome.org/PathwayBrowser/#/R-GGA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Gallus gallus 15379 R-GGA-71261 https://reactome.org/PathwayBrowser/#/R-GGA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Gallus gallus 15379 R-GGA-74247 https://reactome.org/PathwayBrowser/#/R-GGA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Gallus gallus 15379 R-GGA-74258 https://reactome.org/PathwayBrowser/#/R-GGA-74258 XDH oxidizes xanthine to form urate IEA Gallus gallus 15379 R-GGA-76031 https://reactome.org/PathwayBrowser/#/R-GGA-76031 2 H2O2 => O2 + 2 H2O IEA Gallus gallus 15379 R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 15379 R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 15379 R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 15379 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 15379 R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 15379 R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 15379 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 15379 R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 15379 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 15379 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 15379 R-GGA-8847579 https://reactome.org/PathwayBrowser/#/R-GGA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15379 R-GGA-8865107 https://reactome.org/PathwayBrowser/#/R-GGA-8865107 MICAL1 produces NADP+, H2O2 IEA Gallus gallus 15379 R-GGA-8878581 https://reactome.org/PathwayBrowser/#/R-GGA-8878581 TYRP1 oxidises DHICA to IQCA IEA Gallus gallus 15379 R-GGA-888614 https://reactome.org/PathwayBrowser/#/R-GGA-888614 IDO2 dioxygenates L-Trp to NFK IEA Gallus gallus 15379 R-GGA-8956458 https://reactome.org/PathwayBrowser/#/R-GGA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Gallus gallus 15379 R-GGA-8981606 https://reactome.org/PathwayBrowser/#/R-GGA-8981606 Myoglobin binds oxygen IEA Gallus gallus 15379 R-GGA-8981610 https://reactome.org/PathwayBrowser/#/R-GGA-8981610 Neuroglobin binds oxygen IEA Gallus gallus 15379 R-GGA-8981621 https://reactome.org/PathwayBrowser/#/R-GGA-8981621 Neuroglobin:oxygen dissociates IEA Gallus gallus 15379 R-GGA-8981622 https://reactome.org/PathwayBrowser/#/R-GGA-8981622 Myoglobin:oxygen dissociates IEA Gallus gallus 15379 R-GGA-8982617 https://reactome.org/PathwayBrowser/#/R-GGA-8982617 CYGB:O2 dissociates IEA Gallus gallus 15379 R-GGA-9018858 https://reactome.org/PathwayBrowser/#/R-GGA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Gallus gallus 15379 R-GGA-9018859 https://reactome.org/PathwayBrowser/#/R-GGA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Gallus gallus 15379 R-GGA-9018863 https://reactome.org/PathwayBrowser/#/R-GGA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Gallus gallus 15379 R-GGA-9018880 https://reactome.org/PathwayBrowser/#/R-GGA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Gallus gallus 15379 R-GGA-9018894 https://reactome.org/PathwayBrowser/#/R-GGA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Gallus gallus 15379 R-GGA-9020251 https://reactome.org/PathwayBrowser/#/R-GGA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Gallus gallus 15379 R-GGA-9020259 https://reactome.org/PathwayBrowser/#/R-GGA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Gallus gallus 15379 R-GGA-9020261 https://reactome.org/PathwayBrowser/#/R-GGA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Gallus gallus 15379 R-GGA-9020264 https://reactome.org/PathwayBrowser/#/R-GGA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Gallus gallus 15379 R-GGA-9020282 https://reactome.org/PathwayBrowser/#/R-GGA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Gallus gallus 15379 R-GGA-9024997 https://reactome.org/PathwayBrowser/#/R-GGA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Gallus gallus 15379 R-GGA-9025996 https://reactome.org/PathwayBrowser/#/R-GGA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Gallus gallus 15379 R-GGA-9026005 https://reactome.org/PathwayBrowser/#/R-GGA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Gallus gallus 15379 R-GGA-9026405 https://reactome.org/PathwayBrowser/#/R-GGA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Gallus gallus 15379 R-GGA-9026408 https://reactome.org/PathwayBrowser/#/R-GGA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Gallus gallus 15379 R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus 15379 R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 15379 R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 15379 R-GGA-9027532 https://reactome.org/PathwayBrowser/#/R-GGA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Gallus gallus 15379 R-GGA-9027607 https://reactome.org/PathwayBrowser/#/R-GGA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Gallus gallus 15379 R-GGA-9027624 https://reactome.org/PathwayBrowser/#/R-GGA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Gallus gallus 15379 R-GGA-9027627 https://reactome.org/PathwayBrowser/#/R-GGA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Gallus gallus 15379 R-GGA-9027628 https://reactome.org/PathwayBrowser/#/R-GGA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Gallus gallus 15379 R-GGA-9027633 https://reactome.org/PathwayBrowser/#/R-GGA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Gallus gallus 15379 R-GGA-9028255 https://reactome.org/PathwayBrowser/#/R-GGA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Gallus gallus 15379 R-GGA-9037761 https://reactome.org/PathwayBrowser/#/R-GGA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Gallus gallus 15379 R-GGA-917891 https://reactome.org/PathwayBrowser/#/R-GGA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Gallus gallus 15379 R-GGA-917933 https://reactome.org/PathwayBrowser/#/R-GGA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Gallus gallus 15379 R-GGA-9629578 https://reactome.org/PathwayBrowser/#/R-GGA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Gallus gallus 15379 R-GGA-9629591 https://reactome.org/PathwayBrowser/#/R-GGA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Gallus gallus 15379 R-GGA-9629869 https://reactome.org/PathwayBrowser/#/R-GGA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Gallus gallus 15379 R-GGA-9629946 https://reactome.org/PathwayBrowser/#/R-GGA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Gallus gallus 15379 R-GGA-9630022 https://reactome.org/PathwayBrowser/#/R-GGA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Gallus gallus 15379 R-GGA-9630769 https://reactome.org/PathwayBrowser/#/R-GGA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Gallus gallus 15379 R-GGA-9630967 https://reactome.org/PathwayBrowser/#/R-GGA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Gallus gallus 15379 R-GGA-9630993 https://reactome.org/PathwayBrowser/#/R-GGA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Gallus gallus 15379 R-GGA-965019 https://reactome.org/PathwayBrowser/#/R-GGA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Gallus gallus 15379 R-GGA-965079 https://reactome.org/PathwayBrowser/#/R-GGA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Gallus gallus 15379 R-GGA-9709360 https://reactome.org/PathwayBrowser/#/R-GGA-9709360 H2O2 reduces MetHb IEA Gallus gallus 15379 R-GGA-9749986 https://reactome.org/PathwayBrowser/#/R-GGA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Gallus gallus 15379 R-GGA-9750016 https://reactome.org/PathwayBrowser/#/R-GGA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Gallus gallus 15379 R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus 15379 R-GGA-9756138 https://reactome.org/PathwayBrowser/#/R-GGA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Gallus gallus 15379 R-GGA-9756162 https://reactome.org/PathwayBrowser/#/R-GGA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Gallus gallus 15379 R-GGA-9756169 https://reactome.org/PathwayBrowser/#/R-GGA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Gallus gallus 15379 R-GGA-9756180 https://reactome.org/PathwayBrowser/#/R-GGA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Gallus gallus 15379 R-GGA-975635 https://reactome.org/PathwayBrowser/#/R-GGA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Gallus gallus 15379 R-GGA-9758674 https://reactome.org/PathwayBrowser/#/R-GGA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Gallus gallus 15379 R-GGA-9817575 https://reactome.org/PathwayBrowser/#/R-GGA-9817575 ERO1B oxidizes P4HB IEA Gallus gallus 15379 R-HSA-112118 https://reactome.org/PathwayBrowser/#/R-HSA-112118 Oxidative demethylation of 1-meA damaged DNA by ALKBH2 TAS Homo sapiens 15379 R-HSA-112120 https://reactome.org/PathwayBrowser/#/R-HSA-112120 Oxidative demethylation of 3-meC damaged DNA by ALKBH2 TAS Homo sapiens 15379 R-HSA-112121 https://reactome.org/PathwayBrowser/#/R-HSA-112121 Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 TAS Homo sapiens 15379 R-HSA-112123 https://reactome.org/PathwayBrowser/#/R-HSA-112123 Oxidative demethylation of 1-meA damaged DNA By ALKBH3 TAS Homo sapiens 15379 R-HSA-112124 https://reactome.org/PathwayBrowser/#/R-HSA-112124 Oxidative demethylation of 3-meC damaged DNA By ALKBH3 TAS Homo sapiens 15379 R-HSA-112125 https://reactome.org/PathwayBrowser/#/R-HSA-112125 Oxidative dealkylation of 1-EtA damaged DNA by ABH3 TAS Homo sapiens 15379 R-HSA-1222376 https://reactome.org/PathwayBrowser/#/R-HSA-1222376 NOX2 generates superoxide from oxygen TAS Homo sapiens 15379 R-HSA-1222462 https://reactome.org/PathwayBrowser/#/R-HSA-1222462 SodB reduces superoxide to H2O2 TAS Homo sapiens 15379 R-HSA-1222469 https://reactome.org/PathwayBrowser/#/R-HSA-1222469 SodC reduces superoxide to H2O2 TAS Homo sapiens 15379 R-HSA-1222704 https://reactome.org/PathwayBrowser/#/R-HSA-1222704 KatG reduces H2O2 TAS Homo sapiens 15379 R-HSA-1222723 https://reactome.org/PathwayBrowser/#/R-HSA-1222723 Nitric oxide is oxidized to nitrate TAS Homo sapiens 15379 R-HSA-1234164 https://reactome.org/PathwayBrowser/#/R-HSA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) TAS Homo sapiens 15379 R-HSA-1234165 https://reactome.org/PathwayBrowser/#/R-HSA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 15379 R-HSA-1234166 https://reactome.org/PathwayBrowser/#/R-HSA-1234166 Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 15379 R-HSA-1234173 https://reactome.org/PathwayBrowser/#/R-HSA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 15379 R-HSA-1234177 https://reactome.org/PathwayBrowser/#/R-HSA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 15379 R-HSA-1234179 https://reactome.org/PathwayBrowser/#/R-HSA-1234179 Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 15379 R-HSA-1234181 https://reactome.org/PathwayBrowser/#/R-HSA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 15379 R-HSA-1236967 https://reactome.org/PathwayBrowser/#/R-HSA-1236967 Alkalization of the phagosomal lumen by NOX2 TAS Homo sapiens 15379 R-HSA-1237119 https://reactome.org/PathwayBrowser/#/R-HSA-1237119 Acireductone is oxidized to MOB TAS Homo sapiens 15379 R-HSA-1237325 https://reactome.org/PathwayBrowser/#/R-HSA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen TAS Homo sapiens 15379 R-HSA-1247668 https://reactome.org/PathwayBrowser/#/R-HSA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 TAS Homo sapiens 15379 R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 15379 R-HSA-140355 https://reactome.org/PathwayBrowser/#/R-HSA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 TAS Homo sapiens 15379 R-HSA-141186 https://reactome.org/PathwayBrowser/#/R-HSA-141186 MAOA:FAD oxidatively deaminates of 5HT TAS Homo sapiens 15379 R-HSA-141200 https://reactome.org/PathwayBrowser/#/R-HSA-141200 MAOB:FAD oxidatively deaminates of PEA TAS Homo sapiens 15379 R-HSA-141202 https://reactome.org/PathwayBrowser/#/R-HSA-141202 MAOB:FAD oxidatively deaminates TYR TAS Homo sapiens 15379 R-HSA-141341 https://reactome.org/PathwayBrowser/#/R-HSA-141341 SMOX-3 oxidises SPN to SPM TAS Homo sapiens 15379 R-HSA-141348 https://reactome.org/PathwayBrowser/#/R-HSA-141348 PAO:FAD oxidises NASPM to PTCN TAS Homo sapiens 15379 R-HSA-141351 https://reactome.org/PathwayBrowser/#/R-HSA-141351 PAOX:FAD oxidises NASPN to SPM TAS Homo sapiens 15379 R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 15379 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 15379 R-HSA-1562603 https://reactome.org/PathwayBrowser/#/R-HSA-1562603 BfrB stores iron TAS Homo sapiens 15379 R-HSA-1562604 https://reactome.org/PathwayBrowser/#/R-HSA-1562604 BfrA stores iron TAS Homo sapiens 15379 R-HSA-1562626 https://reactome.org/PathwayBrowser/#/R-HSA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) TAS Homo sapiens 15379 R-HSA-156526 https://reactome.org/PathwayBrowser/#/R-HSA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO TAS Homo sapiens 15379 R-HSA-159752 https://reactome.org/PathwayBrowser/#/R-HSA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) TAS Homo sapiens 15379 R-HSA-159761 https://reactome.org/PathwayBrowser/#/R-HSA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) TAS Homo sapiens 15379 R-HSA-159795 https://reactome.org/PathwayBrowser/#/R-HSA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) TAS Homo sapiens 15379 R-HSA-159803 https://reactome.org/PathwayBrowser/#/R-HSA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) TAS Homo sapiens 15379 R-HSA-159819 https://reactome.org/PathwayBrowser/#/R-HSA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) TAS Homo sapiens 15379 R-HSA-159826 https://reactome.org/PathwayBrowser/#/R-HSA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) TAS Homo sapiens 15379 R-HSA-1614544 https://reactome.org/PathwayBrowser/#/R-HSA-1614544 Sulfite is oxidized to sulfate TAS Homo sapiens 15379 R-HSA-1614605 https://reactome.org/PathwayBrowser/#/R-HSA-1614605 Persulfide sulfur is dioxygenated TAS Homo sapiens 15379 R-HSA-1614645 https://reactome.org/PathwayBrowser/#/R-HSA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine TAS Homo sapiens 15379 R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 15379 R-HSA-163810 https://reactome.org/PathwayBrowser/#/R-HSA-163810 GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6) IEA Homo sapiens 15379 R-HSA-163820 https://reactome.org/PathwayBrowser/#/R-HSA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) TAS Homo sapiens 15379 R-HSA-1650808 https://reactome.org/PathwayBrowser/#/R-HSA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines TAS Homo sapiens 15379 R-HSA-1655453 https://reactome.org/PathwayBrowser/#/R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU TAS Homo sapiens 15379 R-HSA-189398 https://reactome.org/PathwayBrowser/#/R-HSA-189398 HMOX1 dimer, HMOX2 cleave heme TAS Homo sapiens 15379 R-HSA-189421 https://reactome.org/PathwayBrowser/#/R-HSA-189421 CPO transforms COPRO3 to PPGEN9 TAS Homo sapiens 15379 R-HSA-189423 https://reactome.org/PathwayBrowser/#/R-HSA-189423 PPO oxidises PPGEN9 to PRIN9 TAS Homo sapiens 15379 R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 15379 R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 15379 R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 15379 R-HSA-191999 https://reactome.org/PathwayBrowser/#/R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol TAS Homo sapiens 15379 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 15379 R-HSA-192054 https://reactome.org/PathwayBrowser/#/R-HSA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) TAS Homo sapiens 15379 R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 15379 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 15379 R-HSA-192123 https://reactome.org/PathwayBrowser/#/R-HSA-192123 CYP27A1 27-hydroxylates CHOL TAS Homo sapiens 15379 R-HSA-192157 https://reactome.org/PathwayBrowser/#/R-HSA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE TAS Homo sapiens 15379 R-HSA-192178 https://reactome.org/PathwayBrowser/#/R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL TAS Homo sapiens 15379 R-HSA-192335 https://reactome.org/PathwayBrowser/#/R-HSA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) TAS Homo sapiens 15379 R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 15379 R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 15379 R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 15379 R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 15379 R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 15379 R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 15379 R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 15379 R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 15379 R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 15379 R-HSA-193369 https://reactome.org/PathwayBrowser/#/R-HSA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA TAS Homo sapiens 15379 R-HSA-193393 https://reactome.org/PathwayBrowser/#/R-HSA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol TAS Homo sapiens 15379 R-HSA-193460 https://reactome.org/PathwayBrowser/#/R-HSA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) TAS Homo sapiens 15379 R-HSA-193709 https://reactome.org/PathwayBrowser/#/R-HSA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL TAS Homo sapiens 15379 R-HSA-193713 https://reactome.org/PathwayBrowser/#/R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) TAS Homo sapiens 15379 R-HSA-193719 https://reactome.org/PathwayBrowser/#/R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 15379 R-HSA-193737 https://reactome.org/PathwayBrowser/#/R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) TAS Homo sapiens 15379 R-HSA-193780 https://reactome.org/PathwayBrowser/#/R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al TAS Homo sapiens 15379 R-HSA-193787 https://reactome.org/PathwayBrowser/#/R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol TAS Homo sapiens 15379 R-HSA-193792 https://reactome.org/PathwayBrowser/#/R-HSA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 15379 R-HSA-193845 https://reactome.org/PathwayBrowser/#/R-HSA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE TAS Homo sapiens 15379 R-HSA-193964 https://reactome.org/PathwayBrowser/#/R-HSA-193964 CYP21A2 21-hydroxylates PROG TAS Homo sapiens 15379 R-HSA-193965 https://reactome.org/PathwayBrowser/#/R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO TAS Homo sapiens 15379 R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 15379 R-HSA-193995 https://reactome.org/PathwayBrowser/#/R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST TAS Homo sapiens 15379 R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 15379 R-HSA-194017 https://reactome.org/PathwayBrowser/#/R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST TAS Homo sapiens 15379 R-HSA-194641 https://reactome.org/PathwayBrowser/#/R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15379 R-HSA-194669 https://reactome.org/PathwayBrowser/#/R-HSA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15379 R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 15379 R-HSA-195664 https://reactome.org/PathwayBrowser/#/R-HSA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol TAS Homo sapiens 15379 R-HSA-1980233 https://reactome.org/PathwayBrowser/#/R-HSA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen TAS Homo sapiens 15379 R-HSA-1981104 https://reactome.org/PathwayBrowser/#/R-HSA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines TAS Homo sapiens 15379 R-HSA-198563 https://reactome.org/PathwayBrowser/#/R-HSA-198563 IDO1 dioxygenates L-Trp to NFK TAS Homo sapiens 15379 R-HSA-2002466 https://reactome.org/PathwayBrowser/#/R-HSA-2002466 Formation of allysine by LOX TAS Homo sapiens 15379 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 15379 R-HSA-2046084 https://reactome.org/PathwayBrowser/#/R-HSA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA TAS Homo sapiens 15379 R-HSA-2046089 https://reactome.org/PathwayBrowser/#/R-HSA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA TAS Homo sapiens 15379 R-HSA-2046092 https://reactome.org/PathwayBrowser/#/R-HSA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA TAS Homo sapiens 15379 R-HSA-2046096 https://reactome.org/PathwayBrowser/#/R-HSA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA TAS Homo sapiens 15379 R-HSA-2046097 https://reactome.org/PathwayBrowser/#/R-HSA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 15379 R-HSA-2046099 https://reactome.org/PathwayBrowser/#/R-HSA-2046099 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA IEA Homo sapiens 15379 R-HSA-204662 https://reactome.org/PathwayBrowser/#/R-HSA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A TAS Homo sapiens 15379 R-HSA-2066787 https://reactome.org/PathwayBrowser/#/R-HSA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA TAS Homo sapiens 15379 R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 15379 R-HSA-209823 https://reactome.org/PathwayBrowser/#/R-HSA-209823 Tyrosine is hydroxylated to dopa TAS Homo sapiens 15379 R-HSA-209828 https://reactome.org/PathwayBrowser/#/R-HSA-209828 Tryptophan is hydroxylated TAS Homo sapiens 15379 R-HSA-209845 https://reactome.org/PathwayBrowser/#/R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D TAS Homo sapiens 15379 R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 15379 R-HSA-209891 https://reactome.org/PathwayBrowser/#/R-HSA-209891 Dopamine is oxidised to noradrenaline TAS Homo sapiens 15379 R-HSA-211873 https://reactome.org/PathwayBrowser/#/R-HSA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 TAS Homo sapiens 15379 R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 15379 R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 15379 R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 15379 R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 15379 R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 15379 R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 15379 R-HSA-211923 https://reactome.org/PathwayBrowser/#/R-HSA-211923 CYP26C1 4-hydroxylates 9cRA TAS Homo sapiens 15379 R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 15379 R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 15379 R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 15379 R-HSA-211950 https://reactome.org/PathwayBrowser/#/R-HSA-211950 CYP24A1 24-hydroxylates CTL TAS Homo sapiens 15379 R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 15379 R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 15379 R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 15379 R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 15379 R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 15379 R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 15379 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 15379 R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 15379 R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 15379 R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 15379 R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 15379 R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 15379 R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 15379 R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 15379 R-HSA-2160492 https://reactome.org/PathwayBrowser/#/R-HSA-2160492 IL4I1:FAD oxidises L-Phe to kPPV TAS Homo sapiens 15379 R-HSA-2161745 https://reactome.org/PathwayBrowser/#/R-HSA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15379 R-HSA-2161775 https://reactome.org/PathwayBrowser/#/R-HSA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 TAS Homo sapiens 15379 R-HSA-2161792 https://reactome.org/PathwayBrowser/#/R-HSA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15379 R-HSA-2161794 https://reactome.org/PathwayBrowser/#/R-HSA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 TAS Homo sapiens 15379 R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) TAS Homo sapiens 15379 R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 15379 R-HSA-2161890 https://reactome.org/PathwayBrowser/#/R-HSA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) TAS Homo sapiens 15379 R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) TAS Homo sapiens 15379 R-HSA-2161907 https://reactome.org/PathwayBrowser/#/R-HSA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 TAS Homo sapiens 15379 R-HSA-2161917 https://reactome.org/PathwayBrowser/#/R-HSA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 TAS Homo sapiens 15379 R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 15379 R-HSA-2161950 https://reactome.org/PathwayBrowser/#/R-HSA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B TAS Homo sapiens 15379 R-HSA-2161951 https://reactome.org/PathwayBrowser/#/R-HSA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 TAS Homo sapiens 15379 R-HSA-2161964 https://reactome.org/PathwayBrowser/#/R-HSA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 TAS Homo sapiens 15379 R-HSA-2161979 https://reactome.org/PathwayBrowser/#/R-HSA-2161979 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH TAS Homo sapiens 15379 R-HSA-2162002 https://reactome.org/PathwayBrowser/#/R-HSA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B TAS Homo sapiens 15379 R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB IEA Homo sapiens 15379 R-HSA-2162191 https://reactome.org/PathwayBrowser/#/R-HSA-2162191 Unknown enzyme hydroxylates DMPhOH IEA Homo sapiens 15379 R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 15379 R-HSA-2168883 https://reactome.org/PathwayBrowser/#/R-HSA-2168883 Haptoglobin:Hemoglobin binds CD163 TAS Homo sapiens 15379 R-HSA-2168885 https://reactome.org/PathwayBrowser/#/R-HSA-2168885 Haptoglobin binds Hemoglobin TAS Homo sapiens 15379 R-HSA-2168889 https://reactome.org/PathwayBrowser/#/R-HSA-2168889 Haptoglobin-related Protein binds Hemoglobin TAS Homo sapiens 15379 R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 15379 R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 15379 R-HSA-2172678 https://reactome.org/PathwayBrowser/#/R-HSA-2172678 PHF8 demethylates histone H4K20me1 TAS Homo sapiens 15379 R-HSA-2230938 https://reactome.org/PathwayBrowser/#/R-HSA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed TAS Homo sapiens 15379 R-HSA-2309787 https://reactome.org/PathwayBrowser/#/R-HSA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 TAS Homo sapiens 15379 R-HSA-2395340 https://reactome.org/PathwayBrowser/#/R-HSA-2395340 Formation of hydroxyallysine by LOX TAS Homo sapiens 15379 R-HSA-265296 https://reactome.org/PathwayBrowser/#/R-HSA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 TAS Homo sapiens 15379 R-HSA-3204311 https://reactome.org/PathwayBrowser/#/R-HSA-3204311 AOX1 oxidises PXL to PDXate TAS Homo sapiens 15379 R-HSA-3299680 https://reactome.org/PathwayBrowser/#/R-HSA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) TAS Homo sapiens 15379 R-HSA-3299682 https://reactome.org/PathwayBrowser/#/R-HSA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) TAS Homo sapiens 15379 R-HSA-3299691 https://reactome.org/PathwayBrowser/#/R-HSA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) TAS Homo sapiens 15379 R-HSA-3341294 https://reactome.org/PathwayBrowser/#/R-HSA-3341294 Superoxide reduces cytochrome c TAS Homo sapiens 15379 R-HSA-374909 https://reactome.org/PathwayBrowser/#/R-HSA-374909 Catabolism of Noradrenaline TAS Homo sapiens 15379 R-HSA-3777112 https://reactome.org/PathwayBrowser/#/R-HSA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) TAS Homo sapiens 15379 R-HSA-379382 https://reactome.org/PathwayBrowser/#/R-HSA-379382 MAOA:FAD deaminates DA to DOPAC TAS Homo sapiens 15379 R-HSA-379395 https://reactome.org/PathwayBrowser/#/R-HSA-379395 MAOA:FAD deaminates 3MT to HVA TAS Homo sapiens 15379 R-HSA-389639 https://reactome.org/PathwayBrowser/#/R-HSA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 TAS Homo sapiens 15379 R-HSA-389821 https://reactome.org/PathwayBrowser/#/R-HSA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ TAS Homo sapiens 15379 R-HSA-389842 https://reactome.org/PathwayBrowser/#/R-HSA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate TAS Homo sapiens 15379 R-HSA-389862 https://reactome.org/PathwayBrowser/#/R-HSA-389862 Conversion of glyoxylate to oxalate TAS Homo sapiens 15379 R-HSA-389889 https://reactome.org/PathwayBrowser/#/R-HSA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA TAS Homo sapiens 15379 R-HSA-389891 https://reactome.org/PathwayBrowser/#/R-HSA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) TAS Homo sapiens 15379 R-HSA-390256 https://reactome.org/PathwayBrowser/#/R-HSA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 TAS Homo sapiens 15379 R-HSA-390276 https://reactome.org/PathwayBrowser/#/R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA TAS Homo sapiens 15379 R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA TAS Homo sapiens 15379 R-HSA-418436 https://reactome.org/PathwayBrowser/#/R-HSA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) TAS Homo sapiens 15379 R-HSA-428259 https://reactome.org/PathwayBrowser/#/R-HSA-428259 DEGS1 dehydrogenates dihydroceramide TAS Homo sapiens 15379 R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 15379 R-HSA-4722133 https://reactome.org/PathwayBrowser/#/R-HSA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 TAS Homo sapiens 15379 R-HSA-4724279 https://reactome.org/PathwayBrowser/#/R-HSA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 TAS Homo sapiens 15379 R-HSA-4724284 https://reactome.org/PathwayBrowser/#/R-HSA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 TAS Homo sapiens 15379 R-HSA-4754176 https://reactome.org/PathwayBrowser/#/R-HSA-4754176 JMJD6 demethylates MeR3-histone H3 TAS Homo sapiens 15379 R-HSA-4754181 https://reactome.org/PathwayBrowser/#/R-HSA-4754181 KDM5A-D demethylate Me2K5-histone H3 TAS Homo sapiens 15379 R-HSA-4754187 https://reactome.org/PathwayBrowser/#/R-HSA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 TAS Homo sapiens 15379 R-HSA-5164399 https://reactome.org/PathwayBrowser/#/R-HSA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION TAS Homo sapiens 15379 R-HSA-5218841 https://reactome.org/PathwayBrowser/#/R-HSA-5218841 NADPH oxidase 2 generates superoxide from oxygen TAS Homo sapiens 15379 R-HSA-5220952 https://reactome.org/PathwayBrowser/#/R-HSA-5220952 TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine IEA Homo sapiens 15379 R-HSA-5220990 https://reactome.org/PathwayBrowser/#/R-HSA-5220990 TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine IEA Homo sapiens 15379 R-HSA-5221014 https://reactome.org/PathwayBrowser/#/R-HSA-5221014 TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine IEA Homo sapiens 15379 R-HSA-5340214 https://reactome.org/PathwayBrowser/#/R-HSA-5340214 CYGB binds O2 TAS Homo sapiens 15379 R-HSA-5340226 https://reactome.org/PathwayBrowser/#/R-HSA-5340226 CYGB dioxygenates NO TAS Homo sapiens 15379 R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 15379 R-HSA-5423117 https://reactome.org/PathwayBrowser/#/R-HSA-5423117 PHF8 demethylates MeK21-histone H4 TAS Homo sapiens 15379 R-HSA-5423647 https://reactome.org/PathwayBrowser/#/R-HSA-5423647 CYP2A13 oxidises AFM1 to AFM1E TAS Homo sapiens 15379 R-HSA-5423664 https://reactome.org/PathwayBrowser/#/R-HSA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 TAS Homo sapiens 15379 R-HSA-5423672 https://reactome.org/PathwayBrowser/#/R-HSA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO TAS Homo sapiens 15379 R-HSA-5423678 https://reactome.org/PathwayBrowser/#/R-HSA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 TAS Homo sapiens 15379 R-HSA-5580269 https://reactome.org/PathwayBrowser/#/R-HSA-5580269 Defective CYP11A1 does not cleave 20a,22b-DHCHOL TAS Homo sapiens 15379 R-HSA-5580292 https://reactome.org/PathwayBrowser/#/R-HSA-5580292 Defective CYP11B1 does not oxidise 11DCORT TAS Homo sapiens 15379 R-HSA-5600598 https://reactome.org/PathwayBrowser/#/R-HSA-5600598 Defective CYP11B2 does not oxidise 11DCORST TAS Homo sapiens 15379 R-HSA-5601843 https://reactome.org/PathwayBrowser/#/R-HSA-5601843 Defective CYP17A1 does not 17-hydroxylate PREG TAS Homo sapiens 15379 R-HSA-5601849 https://reactome.org/PathwayBrowser/#/R-HSA-5601849 Defective CYP19A1 does not convert ANDST to E1 TAS Homo sapiens 15379 R-HSA-5601976 https://reactome.org/PathwayBrowser/#/R-HSA-5601976 Defective CYP21A2 does not 21-hydroxylate PROG TAS Homo sapiens 15379 R-HSA-5602004 https://reactome.org/PathwayBrowser/#/R-HSA-5602004 Defective CYP24A1 does not 24-hydroxylate CALTOL TAS Homo sapiens 15379 R-HSA-5602050 https://reactome.org/PathwayBrowser/#/R-HSA-5602050 Defective CYP26C1 does not 4-hydroxylate 9cRA TAS Homo sapiens 15379 R-HSA-5602063 https://reactome.org/PathwayBrowser/#/R-HSA-5602063 Defective CYP26B1 does not 4-hydroxylate atRA TAS Homo sapiens 15379 R-HSA-5602147 https://reactome.org/PathwayBrowser/#/R-HSA-5602147 Defective CYP2R1 does not 25-hydroxylate vitamin D TAS Homo sapiens 15379 R-HSA-5602170 https://reactome.org/PathwayBrowser/#/R-HSA-5602170 CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol TAS Homo sapiens 15379 R-HSA-5602186 https://reactome.org/PathwayBrowser/#/R-HSA-5602186 Defective CYP27B1 does not hydroxylate CDL TAS Homo sapiens 15379 R-HSA-5602242 https://reactome.org/PathwayBrowser/#/R-HSA-5602242 Defective CYP2U1 does not omega-hydroxylate ARA TAS Homo sapiens 15379 R-HSA-5602272 https://reactome.org/PathwayBrowser/#/R-HSA-5602272 Defective CYP4F22 does not 20-hydroxylate TrXA3 TAS Homo sapiens 15379 R-HSA-5602295 https://reactome.org/PathwayBrowser/#/R-HSA-5602295 CYP4F22 20-hydroxylates TrXA3 TAS Homo sapiens 15379 R-HSA-5602885 https://reactome.org/PathwayBrowser/#/R-HSA-5602885 Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL TAS Homo sapiens 15379 R-HSA-5602966 https://reactome.org/PathwayBrowser/#/R-HSA-5602966 Defective FMO3 does not N-oxidise TMA TAS Homo sapiens 15379 R-HSA-5603108 https://reactome.org/PathwayBrowser/#/R-HSA-5603108 Defective MAOA does not oxidatively deaminate 5HT TAS Homo sapiens 15379 R-HSA-5605147 https://reactome.org/PathwayBrowser/#/R-HSA-5605147 Defective CYP1B1 does not 4-hydroxylate EST17b TAS Homo sapiens 15379 R-HSA-5621402 https://reactome.org/PathwayBrowser/#/R-HSA-5621402 Defective CP does not oxidise Fe2+ to Fe3+ TAS Homo sapiens 15379 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 15379 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 15379 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 15379 R-HSA-5649483 https://reactome.org/PathwayBrowser/#/R-HSA-5649483 Defective PAH does not hydroxylate L-Phe to L-Tyr TAS Homo sapiens 15379 R-HSA-5661114 https://reactome.org/PathwayBrowser/#/R-HSA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 TAS Homo sapiens 15379 R-HSA-5661115 https://reactome.org/PathwayBrowser/#/R-HSA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 TAS Homo sapiens 15379 R-HSA-5661116 https://reactome.org/PathwayBrowser/#/R-HSA-5661116 KDM5A-D demethylate Me3K5-histone H3 TAS Homo sapiens 15379 R-HSA-5661120 https://reactome.org/PathwayBrowser/#/R-HSA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 TAS Homo sapiens 15379 R-HSA-5661121 https://reactome.org/PathwayBrowser/#/R-HSA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 TAS Homo sapiens 15379 R-HSA-5661122 https://reactome.org/PathwayBrowser/#/R-HSA-5661122 JMJD6 demethylates Me2R3-histone H3 TAS Homo sapiens 15379 R-HSA-5661124 https://reactome.org/PathwayBrowser/#/R-HSA-5661124 JMJD6 demethylates MeR4-HIST1H4 TAS Homo sapiens 15379 R-HSA-5661125 https://reactome.org/PathwayBrowser/#/R-HSA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 TAS Homo sapiens 15379 R-HSA-5662692 https://reactome.org/PathwayBrowser/#/R-HSA-5662692 Dopa is oxidized to dopaquinone by TYR TAS Homo sapiens 15379 R-HSA-5668629 https://reactome.org/PathwayBrowser/#/R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP TAS Homo sapiens 15379 R-HSA-5668718 https://reactome.org/PathwayBrowser/#/R-HSA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15379 R-HSA-5668731 https://reactome.org/PathwayBrowser/#/R-HSA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15379 R-HSA-5678327 https://reactome.org/PathwayBrowser/#/R-HSA-5678327 MIOX oxidises Ins to GlcA TAS Homo sapiens 15379 R-HSA-5690565 https://reactome.org/PathwayBrowser/#/R-HSA-5690565 SCD desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15379 R-HSA-5691107 https://reactome.org/PathwayBrowser/#/R-HSA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) TAS Homo sapiens 15379 R-HSA-5693681 https://reactome.org/PathwayBrowser/#/R-HSA-5693681 DUOX1,2 reduce O2 to H2O2 TAS Homo sapiens 15379 R-HSA-5693761 https://reactome.org/PathwayBrowser/#/R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids TAS Homo sapiens 15379 R-HSA-5696119 https://reactome.org/PathwayBrowser/#/R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol TAS Homo sapiens 15379 R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 15379 R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 15379 R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 15379 R-HSA-6783455 https://reactome.org/PathwayBrowser/#/R-HSA-6783455 TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 15379 R-HSA-6783880 https://reactome.org/PathwayBrowser/#/R-HSA-6783880 PIPOX oxidises PPCA to P6C TAS Homo sapiens 15379 R-HSA-6785244 https://reactome.org/PathwayBrowser/#/R-HSA-6785244 Defective CYP11B2 does not oxidise 18HCORST TAS Homo sapiens 15379 R-HSA-6785245 https://reactome.org/PathwayBrowser/#/R-HSA-6785245 Defective CYP11B2 does not oxidise CORST TAS Homo sapiens 15379 R-HSA-6786239 https://reactome.org/PathwayBrowser/#/R-HSA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE TAS Homo sapiens 15379 R-HSA-6787811 https://reactome.org/PathwayBrowser/#/R-HSA-6787811 HAO2 tetramer oxidises 2OH-PALM TAS Homo sapiens 15379 R-HSA-6789092 https://reactome.org/PathwayBrowser/#/R-HSA-6789092 NOX2 generates superoxide anion from oxygen TAS Homo sapiens 15379 R-HSA-6799733 https://reactome.org/PathwayBrowser/#/R-HSA-6799733 Semiquinone reacts with oxygen TAS Homo sapiens 15379 R-HSA-6803989 https://reactome.org/PathwayBrowser/#/R-HSA-6803989 Nitric oxide and O2 react to NO2 TAS Homo sapiens 15379 R-HSA-6807053 https://reactome.org/PathwayBrowser/#/R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL TAS Homo sapiens 15379 R-HSA-6807214 https://reactome.org/PathwayBrowser/#/R-HSA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) TAS Homo sapiens 15379 R-HSA-6807557 https://reactome.org/PathwayBrowser/#/R-HSA-6807557 NOX4, NOX5 reduce O2 to O2.- TAS Homo sapiens 15379 R-HSA-6810076 https://reactome.org/PathwayBrowser/#/R-HSA-6810076 DDO oxidizes D-Asp to OA TAS Homo sapiens 15379 R-HSA-6814153 https://reactome.org/PathwayBrowser/#/R-HSA-6814153 ADO oxidises 2AET to HTAU TAS Homo sapiens 15379 R-HSA-71118 https://reactome.org/PathwayBrowser/#/R-HSA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr TAS Homo sapiens 15379 R-HSA-71163 https://reactome.org/PathwayBrowser/#/R-HSA-71163 HPD dioxygenates HPP TAS Homo sapiens 15379 R-HSA-71164 https://reactome.org/PathwayBrowser/#/R-HSA-71164 HGD dioxygenates homogentisate TAS Homo sapiens 15379 R-HSA-71188 https://reactome.org/PathwayBrowser/#/R-HSA-71188 TDO tetramer dioxygenates L-Trp to NFK TAS Homo sapiens 15379 R-HSA-71200 https://reactome.org/PathwayBrowser/#/R-HSA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O TAS Homo sapiens 15379 R-HSA-71218 https://reactome.org/PathwayBrowser/#/R-HSA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde TAS Homo sapiens 15379 R-HSA-71241 https://reactome.org/PathwayBrowser/#/R-HSA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA TAS Homo sapiens 15379 R-HSA-71261 https://reactome.org/PathwayBrowser/#/R-HSA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA TAS Homo sapiens 15379 R-HSA-74247 https://reactome.org/PathwayBrowser/#/R-HSA-74247 XDH oxidizes hypoxanthine to form xanthine TAS Homo sapiens 15379 R-HSA-74258 https://reactome.org/PathwayBrowser/#/R-HSA-74258 XDH oxidizes xanthine to form urate TAS Homo sapiens 15379 R-HSA-76031 https://reactome.org/PathwayBrowser/#/R-HSA-76031 2 H2O2 => O2 + 2 H2O TAS Homo sapiens 15379 R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 15379 R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 15379 R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 15379 R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 15379 R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 15379 R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 15379 R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 15379 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 15379 R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 15379 R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 15379 R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 15379 R-HSA-8847579 https://reactome.org/PathwayBrowser/#/R-HSA-8847579 SCD5 desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15379 R-HSA-8865107 https://reactome.org/PathwayBrowser/#/R-HSA-8865107 MICAL1 produces NADP+, H2O2 TAS Homo sapiens 15379 R-HSA-8878581 https://reactome.org/PathwayBrowser/#/R-HSA-8878581 TYRP1 oxidises DHICA to IQCA TAS Homo sapiens 15379 R-HSA-888614 https://reactome.org/PathwayBrowser/#/R-HSA-888614 IDO2 dioxygenates L-Trp to NFK TAS Homo sapiens 15379 R-HSA-8953398 https://reactome.org/PathwayBrowser/#/R-HSA-8953398 PIR oxygenates quercetin TAS Homo sapiens 15379 R-HSA-8956458 https://reactome.org/PathwayBrowser/#/R-HSA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ TAS Homo sapiens 15379 R-HSA-8981606 https://reactome.org/PathwayBrowser/#/R-HSA-8981606 Myoglobin binds oxygen TAS Homo sapiens 15379 R-HSA-8981610 https://reactome.org/PathwayBrowser/#/R-HSA-8981610 Neuroglobin binds oxygen TAS Homo sapiens 15379 R-HSA-8981621 https://reactome.org/PathwayBrowser/#/R-HSA-8981621 Neuroglobin:oxygen dissociates TAS Homo sapiens 15379 R-HSA-8981622 https://reactome.org/PathwayBrowser/#/R-HSA-8981622 Myoglobin:oxygen dissociates TAS Homo sapiens 15379 R-HSA-8982617 https://reactome.org/PathwayBrowser/#/R-HSA-8982617 CYGB:O2 dissociates TAS Homo sapiens 15379 R-HSA-9018858 https://reactome.org/PathwayBrowser/#/R-HSA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE TAS Homo sapiens 15379 R-HSA-9018859 https://reactome.org/PathwayBrowser/#/R-HSA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE TAS Homo sapiens 15379 R-HSA-9018863 https://reactome.org/PathwayBrowser/#/R-HSA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE TAS Homo sapiens 15379 R-HSA-9018874 https://reactome.org/PathwayBrowser/#/R-HSA-9018874 CYP monooxygenates EPA to 18(S)-HpEPE TAS Homo sapiens 15379 R-HSA-9018880 https://reactome.org/PathwayBrowser/#/R-HSA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE TAS Homo sapiens 15379 R-HSA-9018894 https://reactome.org/PathwayBrowser/#/R-HSA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE TAS Homo sapiens 15379 R-HSA-9018907 https://reactome.org/PathwayBrowser/#/R-HSA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 TAS Homo sapiens 15379 R-HSA-9020251 https://reactome.org/PathwayBrowser/#/R-HSA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA TAS Homo sapiens 15379 R-HSA-9020259 https://reactome.org/PathwayBrowser/#/R-HSA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA TAS Homo sapiens 15379 R-HSA-9020261 https://reactome.org/PathwayBrowser/#/R-HSA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA TAS Homo sapiens 15379 R-HSA-9020264 https://reactome.org/PathwayBrowser/#/R-HSA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA TAS Homo sapiens 15379 R-HSA-9020274 https://reactome.org/PathwayBrowser/#/R-HSA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA TAS Homo sapiens 15379 R-HSA-9020275 https://reactome.org/PathwayBrowser/#/R-HSA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA TAS Homo sapiens 15379 R-HSA-9020282 https://reactome.org/PathwayBrowser/#/R-HSA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA TAS Homo sapiens 15379 R-HSA-9020610 https://reactome.org/PathwayBrowser/#/R-HSA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 TAS Homo sapiens 15379 R-HSA-9024872 https://reactome.org/PathwayBrowser/#/R-HSA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX TAS Homo sapiens 15379 R-HSA-9024997 https://reactome.org/PathwayBrowser/#/R-HSA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA TAS Homo sapiens 15379 R-HSA-9025152 https://reactome.org/PathwayBrowser/#/R-HSA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 TAS Homo sapiens 15379 R-HSA-9025957 https://reactome.org/PathwayBrowser/#/R-HSA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 TAS Homo sapiens 15379 R-HSA-9025996 https://reactome.org/PathwayBrowser/#/R-HSA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 TAS Homo sapiens 15379 R-HSA-9026003 https://reactome.org/PathwayBrowser/#/R-HSA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 TAS Homo sapiens 15379 R-HSA-9026005 https://reactome.org/PathwayBrowser/#/R-HSA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA TAS Homo sapiens 15379 R-HSA-9026006 https://reactome.org/PathwayBrowser/#/R-HSA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 TAS Homo sapiens 15379 R-HSA-9026405 https://reactome.org/PathwayBrowser/#/R-HSA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 TAS Homo sapiens 15379 R-HSA-9026408 https://reactome.org/PathwayBrowser/#/R-HSA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 TAS Homo sapiens 15379 R-HSA-9026918 https://reactome.org/PathwayBrowser/#/R-HSA-9026918 Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA TAS Homo sapiens 15379 R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 15379 R-HSA-9027043 https://reactome.org/PathwayBrowser/#/R-HSA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA TAS Homo sapiens 15379 R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 15379 R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 15379 R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 15379 R-HSA-9027532 https://reactome.org/PathwayBrowser/#/R-HSA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA TAS Homo sapiens 15379 R-HSA-9027607 https://reactome.org/PathwayBrowser/#/R-HSA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 TAS Homo sapiens 15379 R-HSA-9027624 https://reactome.org/PathwayBrowser/#/R-HSA-9027624 ALOX5 oxidises DHA to 7-HDHA TAS Homo sapiens 15379 R-HSA-9027627 https://reactome.org/PathwayBrowser/#/R-HSA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) TAS Homo sapiens 15379 R-HSA-9027628 https://reactome.org/PathwayBrowser/#/R-HSA-9027628 ALOX5 oxidises EPA to 5-HEPE TAS Homo sapiens 15379 R-HSA-9027633 https://reactome.org/PathwayBrowser/#/R-HSA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 TAS Homo sapiens 15379 R-HSA-9028255 https://reactome.org/PathwayBrowser/#/R-HSA-9028255 PTGS2 dimer oxidises EPA to PGH3 TAS Homo sapiens 15379 R-HSA-9035954 https://reactome.org/PathwayBrowser/#/R-HSA-9035954 Defective CYP17A1 does not 17-hydroxylate P4 TAS Homo sapiens 15379 R-HSA-9035956 https://reactome.org/PathwayBrowser/#/R-HSA-9035956 Defective CYP17A1 does not cleave 17aHPROG TAS Homo sapiens 15379 R-HSA-9035960 https://reactome.org/PathwayBrowser/#/R-HSA-9035960 Defective CYP27A1 does not 27-hydroxylate 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 15379 R-HSA-9037761 https://reactome.org/PathwayBrowser/#/R-HSA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 TAS Homo sapiens 15379 R-HSA-917891 https://reactome.org/PathwayBrowser/#/R-HSA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ TAS Homo sapiens 15379 R-HSA-917933 https://reactome.org/PathwayBrowser/#/R-HSA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ TAS Homo sapiens 15379 R-HSA-9629578 https://reactome.org/PathwayBrowser/#/R-HSA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 TAS Homo sapiens 15379 R-HSA-9629591 https://reactome.org/PathwayBrowser/#/R-HSA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 TAS Homo sapiens 15379 R-HSA-9629869 https://reactome.org/PathwayBrowser/#/R-HSA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 TAS Homo sapiens 15379 R-HSA-9629888 https://reactome.org/PathwayBrowser/#/R-HSA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 TAS Homo sapiens 15379 R-HSA-9629946 https://reactome.org/PathwayBrowser/#/R-HSA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 TAS Homo sapiens 15379 R-HSA-9630022 https://reactome.org/PathwayBrowser/#/R-HSA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 TAS Homo sapiens 15379 R-HSA-9630769 https://reactome.org/PathwayBrowser/#/R-HSA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 TAS Homo sapiens 15379 R-HSA-9630967 https://reactome.org/PathwayBrowser/#/R-HSA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A TAS Homo sapiens 15379 R-HSA-9630993 https://reactome.org/PathwayBrowser/#/R-HSA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 TAS Homo sapiens 15379 R-HSA-9631355 https://reactome.org/PathwayBrowser/#/R-HSA-9631355 ASPH:Fe2+ hydroxylates an aspartate residue of F9 IEA Homo sapiens 15379 R-HSA-965019 https://reactome.org/PathwayBrowser/#/R-HSA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP TAS Homo sapiens 15379 R-HSA-965079 https://reactome.org/PathwayBrowser/#/R-HSA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP TAS Homo sapiens 15379 R-HSA-9673231 https://reactome.org/PathwayBrowser/#/R-HSA-9673231 GGCX does not gamma-carboxylate 3D-F9(29-461) (pro-factor IX) TAS Homo sapiens 15379 R-HSA-9673797 https://reactome.org/PathwayBrowser/#/R-HSA-9673797 NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15379 R-HSA-9698758 https://reactome.org/PathwayBrowser/#/R-HSA-9698758 FLT3 ITD- and NOX4-dependent H2O2 production TAS Homo sapiens 15379 R-HSA-9709360 https://reactome.org/PathwayBrowser/#/R-HSA-9709360 H2O2 reduces MetHb TAS Homo sapiens 15379 R-HSA-9727359 https://reactome.org/PathwayBrowser/#/R-HSA-9727359 Keratinocyte of spinosum layer differentiates into keratinocyte of granulosum layer in interfollicular epidermis TAS Homo sapiens 15379 R-HSA-9749986 https://reactome.org/PathwayBrowser/#/R-HSA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA TAS Homo sapiens 15379 R-HSA-9750016 https://reactome.org/PathwayBrowser/#/R-HSA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA TAS Homo sapiens 15379 R-HSA-9753285 https://reactome.org/PathwayBrowser/#/R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI TAS Homo sapiens 15379 R-HSA-9756138 https://reactome.org/PathwayBrowser/#/R-HSA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL TAS Homo sapiens 15379 R-HSA-9756162 https://reactome.org/PathwayBrowser/#/R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV TAS Homo sapiens 15379 R-HSA-9756169 https://reactome.org/PathwayBrowser/#/R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV TAS Homo sapiens 15379 R-HSA-9756180 https://reactome.org/PathwayBrowser/#/R-HSA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL TAS Homo sapiens 15379 R-HSA-975635 https://reactome.org/PathwayBrowser/#/R-HSA-975635 BCMO1:Fe2+ cleaves betaC to atRAL TAS Homo sapiens 15379 R-HSA-9758674 https://reactome.org/PathwayBrowser/#/R-HSA-9758674 CYP3A4 oxidizes PREDN,PREDL TAS Homo sapiens 15379 R-HSA-9794840 https://reactome.org/PathwayBrowser/#/R-HSA-9794840 Cipro is oxidized to oxo-Cipro TAS Homo sapiens 15379 R-HSA-9795134 https://reactome.org/PathwayBrowser/#/R-HSA-9795134 Cipro is sulfonated to sulfo-Cipro TAS Homo sapiens 15379 R-HSA-9817458 https://reactome.org/PathwayBrowser/#/R-HSA-9817458 TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 IEA Homo sapiens 15379 R-HSA-9817575 https://reactome.org/PathwayBrowser/#/R-HSA-9817575 ERO1B oxidizes P4HB TAS Homo sapiens 15379 R-HSA-9822461 https://reactome.org/PathwayBrowser/#/R-HSA-9822461 KDM5B demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 15379 R-HSA-9822467 https://reactome.org/PathwayBrowser/#/R-HSA-9822467 KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 15379 R-HSA-9822914 https://reactome.org/PathwayBrowser/#/R-HSA-9822914 KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 15379 R-HSA-9822985 https://reactome.org/PathwayBrowser/#/R-HSA-9822985 KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 15379 R-MMU-1222376 https://reactome.org/PathwayBrowser/#/R-MMU-1222376 NOX2 generates superoxide from oxygen IEA Mus musculus 15379 R-MMU-1234164 https://reactome.org/PathwayBrowser/#/R-MMU-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Mus musculus 15379 R-MMU-1234165 https://reactome.org/PathwayBrowser/#/R-MMU-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Mus musculus 15379 R-MMU-1234173 https://reactome.org/PathwayBrowser/#/R-MMU-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Mus musculus 15379 R-MMU-1234177 https://reactome.org/PathwayBrowser/#/R-MMU-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Mus musculus 15379 R-MMU-1234181 https://reactome.org/PathwayBrowser/#/R-MMU-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Mus musculus 15379 R-MMU-1236967 https://reactome.org/PathwayBrowser/#/R-MMU-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Mus musculus 15379 R-MMU-1237119 https://reactome.org/PathwayBrowser/#/R-MMU-1237119 Acireductone is oxidized to MOB IEA Mus musculus 15379 R-MMU-1237325 https://reactome.org/PathwayBrowser/#/R-MMU-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Mus musculus 15379 R-MMU-1247668 https://reactome.org/PathwayBrowser/#/R-MMU-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Mus musculus 15379 R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 15379 R-MMU-140355 https://reactome.org/PathwayBrowser/#/R-MMU-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Mus musculus 15379 R-MMU-141186 https://reactome.org/PathwayBrowser/#/R-MMU-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Mus musculus 15379 R-MMU-141200 https://reactome.org/PathwayBrowser/#/R-MMU-141200 MAOB:FAD oxidatively deaminates of PEA IEA Mus musculus 15379 R-MMU-141202 https://reactome.org/PathwayBrowser/#/R-MMU-141202 MAOB:FAD oxidatively deaminates TYR IEA Mus musculus 15379 R-MMU-141341 https://reactome.org/PathwayBrowser/#/R-MMU-141341 SMOX-3 oxidises SPN to SPM IEA Mus musculus 15379 R-MMU-141348 https://reactome.org/PathwayBrowser/#/R-MMU-141348 PAO:FAD oxidises NASPM to PTCN IEA Mus musculus 15379 R-MMU-141351 https://reactome.org/PathwayBrowser/#/R-MMU-141351 PAOX:FAD oxidises NASPN to SPM IEA Mus musculus 15379 R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 15379 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 15379 R-MMU-1562626 https://reactome.org/PathwayBrowser/#/R-MMU-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Mus musculus 15379 R-MMU-156526 https://reactome.org/PathwayBrowser/#/R-MMU-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Mus musculus 15379 R-MMU-159752 https://reactome.org/PathwayBrowser/#/R-MMU-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Mus musculus 15379 R-MMU-159761 https://reactome.org/PathwayBrowser/#/R-MMU-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Mus musculus 15379 R-MMU-159795 https://reactome.org/PathwayBrowser/#/R-MMU-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Mus musculus 15379 R-MMU-159803 https://reactome.org/PathwayBrowser/#/R-MMU-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Mus musculus 15379 R-MMU-159819 https://reactome.org/PathwayBrowser/#/R-MMU-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Mus musculus 15379 R-MMU-159826 https://reactome.org/PathwayBrowser/#/R-MMU-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Mus musculus 15379 R-MMU-1614544 https://reactome.org/PathwayBrowser/#/R-MMU-1614544 Sulfite is oxidized to sulfate IEA Mus musculus 15379 R-MMU-1614605 https://reactome.org/PathwayBrowser/#/R-MMU-1614605 Persulfide sulfur is dioxygenated IEA Mus musculus 15379 R-MMU-1614645 https://reactome.org/PathwayBrowser/#/R-MMU-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Mus musculus 15379 R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 15379 R-MMU-163820 https://reactome.org/PathwayBrowser/#/R-MMU-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Mus musculus 15379 R-MMU-1650808 https://reactome.org/PathwayBrowser/#/R-MMU-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Mus musculus 15379 R-MMU-1655453 https://reactome.org/PathwayBrowser/#/R-MMU-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Mus musculus 15379 R-MMU-189398 https://reactome.org/PathwayBrowser/#/R-MMU-189398 HMOX1 dimer, HMOX2 cleave heme IEA Mus musculus 15379 R-MMU-189421 https://reactome.org/PathwayBrowser/#/R-MMU-189421 CPO transforms COPRO3 to PPGEN9 IEA Mus musculus 15379 R-MMU-189423 https://reactome.org/PathwayBrowser/#/R-MMU-189423 PPO oxidises PPGEN9 to PRIN9 IEA Mus musculus 15379 R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 15379 R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 15379 R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 15379 R-MMU-191999 https://reactome.org/PathwayBrowser/#/R-MMU-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Mus musculus 15379 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 15379 R-MMU-192054 https://reactome.org/PathwayBrowser/#/R-MMU-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Mus musculus 15379 R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 15379 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 15379 R-MMU-192123 https://reactome.org/PathwayBrowser/#/R-MMU-192123 CYP27A1 27-hydroxylates CHOL IEA Mus musculus 15379 R-MMU-192157 https://reactome.org/PathwayBrowser/#/R-MMU-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Mus musculus 15379 R-MMU-192178 https://reactome.org/PathwayBrowser/#/R-MMU-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Mus musculus 15379 R-MMU-192335 https://reactome.org/PathwayBrowser/#/R-MMU-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Mus musculus 15379 R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 15379 R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 15379 R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 15379 R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 15379 R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 15379 R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 15379 R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 15379 R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 15379 R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 15379 R-MMU-193369 https://reactome.org/PathwayBrowser/#/R-MMU-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Mus musculus 15379 R-MMU-193393 https://reactome.org/PathwayBrowser/#/R-MMU-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Mus musculus 15379 R-MMU-193460 https://reactome.org/PathwayBrowser/#/R-MMU-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Mus musculus 15379 R-MMU-193709 https://reactome.org/PathwayBrowser/#/R-MMU-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Mus musculus 15379 R-MMU-193713 https://reactome.org/PathwayBrowser/#/R-MMU-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Mus musculus 15379 R-MMU-193719 https://reactome.org/PathwayBrowser/#/R-MMU-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 15379 R-MMU-193737 https://reactome.org/PathwayBrowser/#/R-MMU-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Mus musculus 15379 R-MMU-193780 https://reactome.org/PathwayBrowser/#/R-MMU-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Mus musculus 15379 R-MMU-193787 https://reactome.org/PathwayBrowser/#/R-MMU-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Mus musculus 15379 R-MMU-193792 https://reactome.org/PathwayBrowser/#/R-MMU-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Mus musculus 15379 R-MMU-193845 https://reactome.org/PathwayBrowser/#/R-MMU-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Mus musculus 15379 R-MMU-193964 https://reactome.org/PathwayBrowser/#/R-MMU-193964 CYP21A2 21-hydroxylates PROG IEA Mus musculus 15379 R-MMU-193965 https://reactome.org/PathwayBrowser/#/R-MMU-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Mus musculus 15379 R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 15379 R-MMU-193995 https://reactome.org/PathwayBrowser/#/R-MMU-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Mus musculus 15379 R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 15379 R-MMU-194017 https://reactome.org/PathwayBrowser/#/R-MMU-194017 CYP11B2 oxidises 11DCORST to CORST IEA Mus musculus 15379 R-MMU-194641 https://reactome.org/PathwayBrowser/#/R-MMU-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15379 R-MMU-194669 https://reactome.org/PathwayBrowser/#/R-MMU-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15379 R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 15379 R-MMU-195664 https://reactome.org/PathwayBrowser/#/R-MMU-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Mus musculus 15379 R-MMU-1980233 https://reactome.org/PathwayBrowser/#/R-MMU-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Mus musculus 15379 R-MMU-1981104 https://reactome.org/PathwayBrowser/#/R-MMU-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Mus musculus 15379 R-MMU-198563 https://reactome.org/PathwayBrowser/#/R-MMU-198563 IDO1 dioxygenates L-Trp to NFK IEA Mus musculus 15379 R-MMU-2002466 https://reactome.org/PathwayBrowser/#/R-MMU-2002466 Formation of allysine by LOX IEA Mus musculus 15379 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 15379 R-MMU-2046084 https://reactome.org/PathwayBrowser/#/R-MMU-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Mus musculus 15379 R-MMU-2046089 https://reactome.org/PathwayBrowser/#/R-MMU-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Mus musculus 15379 R-MMU-2046092 https://reactome.org/PathwayBrowser/#/R-MMU-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Mus musculus 15379 R-MMU-2046096 https://reactome.org/PathwayBrowser/#/R-MMU-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Mus musculus 15379 R-MMU-2046097 https://reactome.org/PathwayBrowser/#/R-MMU-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 15379 R-MMU-204662 https://reactome.org/PathwayBrowser/#/R-MMU-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Mus musculus 15379 R-MMU-2066787 https://reactome.org/PathwayBrowser/#/R-MMU-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Mus musculus 15379 R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 15379 R-MMU-209823 https://reactome.org/PathwayBrowser/#/R-MMU-209823 Tyrosine is hydroxylated to dopa IEA Mus musculus 15379 R-MMU-209828 https://reactome.org/PathwayBrowser/#/R-MMU-209828 Tryptophan is hydroxylated IEA Mus musculus 15379 R-MMU-209845 https://reactome.org/PathwayBrowser/#/R-MMU-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Mus musculus 15379 R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 15379 R-MMU-209891 https://reactome.org/PathwayBrowser/#/R-MMU-209891 Dopamine is oxidised to noradrenaline IEA Mus musculus 15379 R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus 15379 R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 15379 R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 15379 R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 15379 R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 15379 R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 15379 R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 15379 R-MMU-211923 https://reactome.org/PathwayBrowser/#/R-MMU-211923 CYP26C1 4-hydroxylates 9cRA IEA Mus musculus 15379 R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 15379 R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 15379 R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 15379 R-MMU-211950 https://reactome.org/PathwayBrowser/#/R-MMU-211950 CYP24A1 24-hydroxylates CTL IEA Mus musculus 15379 R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 15379 R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 15379 R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 15379 R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 15379 R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 15379 R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 15379 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 15379 R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 15379 R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 15379 R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 15379 R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 15379 R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 15379 R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 15379 R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 15379 R-MMU-2160492 https://reactome.org/PathwayBrowser/#/R-MMU-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Mus musculus 15379 R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus 15379 R-MMU-2161775 https://reactome.org/PathwayBrowser/#/R-MMU-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Mus musculus 15379 R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus 15379 R-MMU-2161794 https://reactome.org/PathwayBrowser/#/R-MMU-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Mus musculus 15379 R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Mus musculus 15379 R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 15379 R-MMU-2161890 https://reactome.org/PathwayBrowser/#/R-MMU-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Mus musculus 15379 R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Mus musculus 15379 R-MMU-2161907 https://reactome.org/PathwayBrowser/#/R-MMU-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Mus musculus 15379 R-MMU-2161917 https://reactome.org/PathwayBrowser/#/R-MMU-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Mus musculus 15379 R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 15379 R-MMU-2161950 https://reactome.org/PathwayBrowser/#/R-MMU-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Mus musculus 15379 R-MMU-2161951 https://reactome.org/PathwayBrowser/#/R-MMU-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Mus musculus 15379 R-MMU-2161964 https://reactome.org/PathwayBrowser/#/R-MMU-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Mus musculus 15379 R-MMU-2162002 https://reactome.org/PathwayBrowser/#/R-MMU-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Mus musculus 15379 R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 15379 R-MMU-2168883 https://reactome.org/PathwayBrowser/#/R-MMU-2168883 Haptoglobin:Hemoglobin binds CD163 IEA Mus musculus 15379 R-MMU-2168885 https://reactome.org/PathwayBrowser/#/R-MMU-2168885 Haptoglobin binds Hemoglobin IEA Mus musculus 15379 R-MMU-2168889 https://reactome.org/PathwayBrowser/#/R-MMU-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Mus musculus 15379 R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 15379 R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 15379 R-MMU-2230938 https://reactome.org/PathwayBrowser/#/R-MMU-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Mus musculus 15379 R-MMU-2309787 https://reactome.org/PathwayBrowser/#/R-MMU-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Mus musculus 15379 R-MMU-2395340 https://reactome.org/PathwayBrowser/#/R-MMU-2395340 Formation of hydroxyallysine by LOX IEA Mus musculus 15379 R-MMU-265296 https://reactome.org/PathwayBrowser/#/R-MMU-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Mus musculus 15379 R-MMU-3204311 https://reactome.org/PathwayBrowser/#/R-MMU-3204311 AOX1 oxidises PXL to PDXate IEA Mus musculus 15379 R-MMU-3299680 https://reactome.org/PathwayBrowser/#/R-MMU-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Mus musculus 15379 R-MMU-3299682 https://reactome.org/PathwayBrowser/#/R-MMU-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Mus musculus 15379 R-MMU-3299691 https://reactome.org/PathwayBrowser/#/R-MMU-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Mus musculus 15379 R-MMU-3341294 https://reactome.org/PathwayBrowser/#/R-MMU-3341294 Superoxide reduces cytochrome c IEA Mus musculus 15379 R-MMU-374909 https://reactome.org/PathwayBrowser/#/R-MMU-374909 Catabolism of Noradrenaline IEA Mus musculus 15379 R-MMU-3777112 https://reactome.org/PathwayBrowser/#/R-MMU-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Mus musculus 15379 R-MMU-379382 https://reactome.org/PathwayBrowser/#/R-MMU-379382 MAOA:FAD deaminates DA to DOPAC IEA Mus musculus 15379 R-MMU-379395 https://reactome.org/PathwayBrowser/#/R-MMU-379395 MAOA:FAD deaminates 3MT to HVA IEA Mus musculus 15379 R-MMU-389639 https://reactome.org/PathwayBrowser/#/R-MMU-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Mus musculus 15379 R-MMU-389821 https://reactome.org/PathwayBrowser/#/R-MMU-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Mus musculus 15379 R-MMU-389842 https://reactome.org/PathwayBrowser/#/R-MMU-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Mus musculus 15379 R-MMU-389862 https://reactome.org/PathwayBrowser/#/R-MMU-389862 Conversion of glyoxylate to oxalate IEA Mus musculus 15379 R-MMU-389889 https://reactome.org/PathwayBrowser/#/R-MMU-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Mus musculus 15379 R-MMU-389891 https://reactome.org/PathwayBrowser/#/R-MMU-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Mus musculus 15379 R-MMU-390256 https://reactome.org/PathwayBrowser/#/R-MMU-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Mus musculus 15379 R-MMU-418436 https://reactome.org/PathwayBrowser/#/R-MMU-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Mus musculus 15379 R-MMU-428259 https://reactome.org/PathwayBrowser/#/R-MMU-428259 DEGS1 dehydrogenates dihydroceramide IEA Mus musculus 15379 R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 15379 R-MMU-4722133 https://reactome.org/PathwayBrowser/#/R-MMU-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Mus musculus 15379 R-MMU-4724279 https://reactome.org/PathwayBrowser/#/R-MMU-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Mus musculus 15379 R-MMU-4724284 https://reactome.org/PathwayBrowser/#/R-MMU-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Mus musculus 15379 R-MMU-4754176 https://reactome.org/PathwayBrowser/#/R-MMU-4754176 JMJD6 demethylates MeR3-histone H3 IEA Mus musculus 15379 R-MMU-4754181 https://reactome.org/PathwayBrowser/#/R-MMU-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Mus musculus 15379 R-MMU-4754187 https://reactome.org/PathwayBrowser/#/R-MMU-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Mus musculus 15379 R-MMU-5164399 https://reactome.org/PathwayBrowser/#/R-MMU-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Mus musculus 15379 R-MMU-5218841 https://reactome.org/PathwayBrowser/#/R-MMU-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Mus musculus 15379 R-MMU-5220931 https://reactome.org/PathwayBrowser/#/R-MMU-5220931 Tet1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine TAS Mus musculus 15379 R-MMU-5220936 https://reactome.org/PathwayBrowser/#/R-MMU-5220936 Tet1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine TAS Mus musculus 15379 R-MMU-5220944 https://reactome.org/PathwayBrowser/#/R-MMU-5220944 Tet1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine TAS Mus musculus 15379 R-MMU-5340214 https://reactome.org/PathwayBrowser/#/R-MMU-5340214 CYGB binds O2 IEA Mus musculus 15379 R-MMU-5340226 https://reactome.org/PathwayBrowser/#/R-MMU-5340226 CYGB dioxygenates NO IEA Mus musculus 15379 R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 15379 R-MMU-5423117 https://reactome.org/PathwayBrowser/#/R-MMU-5423117 PHF8 demethylates MeK21-histone H4 IEA Mus musculus 15379 R-MMU-5423647 https://reactome.org/PathwayBrowser/#/R-MMU-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Mus musculus 15379 R-MMU-5423664 https://reactome.org/PathwayBrowser/#/R-MMU-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Mus musculus 15379 R-MMU-5423672 https://reactome.org/PathwayBrowser/#/R-MMU-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Mus musculus 15379 R-MMU-5423678 https://reactome.org/PathwayBrowser/#/R-MMU-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Mus musculus 15379 R-MMU-5602295 https://reactome.org/PathwayBrowser/#/R-MMU-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Mus musculus 15379 R-MMU-5661114 https://reactome.org/PathwayBrowser/#/R-MMU-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Mus musculus 15379 R-MMU-5661115 https://reactome.org/PathwayBrowser/#/R-MMU-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Mus musculus 15379 R-MMU-5661116 https://reactome.org/PathwayBrowser/#/R-MMU-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Mus musculus 15379 R-MMU-5661120 https://reactome.org/PathwayBrowser/#/R-MMU-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Mus musculus 15379 R-MMU-5661121 https://reactome.org/PathwayBrowser/#/R-MMU-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Mus musculus 15379 R-MMU-5661122 https://reactome.org/PathwayBrowser/#/R-MMU-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Mus musculus 15379 R-MMU-5661124 https://reactome.org/PathwayBrowser/#/R-MMU-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Mus musculus 15379 R-MMU-5661125 https://reactome.org/PathwayBrowser/#/R-MMU-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Mus musculus 15379 R-MMU-5662692 https://reactome.org/PathwayBrowser/#/R-MMU-5662692 Dopa is oxidized to dopaquinone by TYR IEA Mus musculus 15379 R-MMU-5668629 https://reactome.org/PathwayBrowser/#/R-MMU-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Mus musculus 15379 R-MMU-5668718 https://reactome.org/PathwayBrowser/#/R-MMU-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 15379 R-MMU-5668731 https://reactome.org/PathwayBrowser/#/R-MMU-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 15379 R-MMU-5678327 https://reactome.org/PathwayBrowser/#/R-MMU-5678327 MIOX oxidises Ins to GlcA IEA Mus musculus 15379 R-MMU-5690565 https://reactome.org/PathwayBrowser/#/R-MMU-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Mus musculus 15379 R-MMU-5691107 https://reactome.org/PathwayBrowser/#/R-MMU-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Mus musculus 15379 R-MMU-5693681 https://reactome.org/PathwayBrowser/#/R-MMU-5693681 DUOX1,2 reduce O2 to H2O2 IEA Mus musculus 15379 R-MMU-5693761 https://reactome.org/PathwayBrowser/#/R-MMU-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Mus musculus 15379 R-MMU-5696119 https://reactome.org/PathwayBrowser/#/R-MMU-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Mus musculus 15379 R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 15379 R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 15379 R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 15379 R-MMU-6783880 https://reactome.org/PathwayBrowser/#/R-MMU-6783880 PIPOX oxidises PPCA to P6C IEA Mus musculus 15379 R-MMU-6786239 https://reactome.org/PathwayBrowser/#/R-MMU-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Mus musculus 15379 R-MMU-6787811 https://reactome.org/PathwayBrowser/#/R-MMU-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Mus musculus 15379 R-MMU-6789092 https://reactome.org/PathwayBrowser/#/R-MMU-6789092 NOX2 generates superoxide anion from oxygen IEA Mus musculus 15379 R-MMU-6807053 https://reactome.org/PathwayBrowser/#/R-MMU-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Mus musculus 15379 R-MMU-6807214 https://reactome.org/PathwayBrowser/#/R-MMU-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Mus musculus 15379 R-MMU-6807557 https://reactome.org/PathwayBrowser/#/R-MMU-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Mus musculus 15379 R-MMU-6810076 https://reactome.org/PathwayBrowser/#/R-MMU-6810076 DDO oxidizes D-Asp to OA IEA Mus musculus 15379 R-MMU-6814153 https://reactome.org/PathwayBrowser/#/R-MMU-6814153 ADO oxidises 2AET to HTAU IEA Mus musculus 15379 R-MMU-71118 https://reactome.org/PathwayBrowser/#/R-MMU-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Mus musculus 15379 R-MMU-71163 https://reactome.org/PathwayBrowser/#/R-MMU-71163 HPD dioxygenates HPP IEA Mus musculus 15379 R-MMU-71164 https://reactome.org/PathwayBrowser/#/R-MMU-71164 HGD dioxygenates homogentisate IEA Mus musculus 15379 R-MMU-71188 https://reactome.org/PathwayBrowser/#/R-MMU-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Mus musculus 15379 R-MMU-71200 https://reactome.org/PathwayBrowser/#/R-MMU-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Mus musculus 15379 R-MMU-71218 https://reactome.org/PathwayBrowser/#/R-MMU-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Mus musculus 15379 R-MMU-71241 https://reactome.org/PathwayBrowser/#/R-MMU-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Mus musculus 15379 R-MMU-71261 https://reactome.org/PathwayBrowser/#/R-MMU-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Mus musculus 15379 R-MMU-74247 https://reactome.org/PathwayBrowser/#/R-MMU-74247 XDH oxidizes hypoxanthine to form xanthine IEA Mus musculus 15379 R-MMU-74258 https://reactome.org/PathwayBrowser/#/R-MMU-74258 XDH oxidizes xanthine to form urate IEA Mus musculus 15379 R-MMU-76031 https://reactome.org/PathwayBrowser/#/R-MMU-76031 2 H2O2 => O2 + 2 H2O IEA Mus musculus 15379 R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 15379 R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 15379 R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 15379 R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 15379 R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 15379 R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 15379 R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 15379 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 15379 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 15379 R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 15379 R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 15379 R-MMU-8878581 https://reactome.org/PathwayBrowser/#/R-MMU-8878581 TYRP1 oxidises DHICA to IQCA IEA Mus musculus 15379 R-MMU-888614 https://reactome.org/PathwayBrowser/#/R-MMU-888614 IDO2 dioxygenates L-Trp to NFK IEA Mus musculus 15379 R-MMU-8953398 https://reactome.org/PathwayBrowser/#/R-MMU-8953398 PIR oxygenates quercetin IEA Mus musculus 15379 R-MMU-8956458 https://reactome.org/PathwayBrowser/#/R-MMU-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Mus musculus 15379 R-MMU-8981606 https://reactome.org/PathwayBrowser/#/R-MMU-8981606 Myoglobin binds oxygen IEA Mus musculus 15379 R-MMU-8981610 https://reactome.org/PathwayBrowser/#/R-MMU-8981610 Neuroglobin binds oxygen IEA Mus musculus 15379 R-MMU-8981621 https://reactome.org/PathwayBrowser/#/R-MMU-8981621 Neuroglobin:oxygen dissociates IEA Mus musculus 15379 R-MMU-8981622 https://reactome.org/PathwayBrowser/#/R-MMU-8981622 Myoglobin:oxygen dissociates IEA Mus musculus 15379 R-MMU-8982617 https://reactome.org/PathwayBrowser/#/R-MMU-8982617 CYGB:O2 dissociates IEA Mus musculus 15379 R-MMU-9018858 https://reactome.org/PathwayBrowser/#/R-MMU-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Mus musculus 15379 R-MMU-9018859 https://reactome.org/PathwayBrowser/#/R-MMU-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Mus musculus 15379 R-MMU-9018863 https://reactome.org/PathwayBrowser/#/R-MMU-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Mus musculus 15379 R-MMU-9018880 https://reactome.org/PathwayBrowser/#/R-MMU-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Mus musculus 15379 R-MMU-9018894 https://reactome.org/PathwayBrowser/#/R-MMU-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Mus musculus 15379 R-MMU-9018907 https://reactome.org/PathwayBrowser/#/R-MMU-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Mus musculus 15379 R-MMU-9020251 https://reactome.org/PathwayBrowser/#/R-MMU-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Mus musculus 15379 R-MMU-9020259 https://reactome.org/PathwayBrowser/#/R-MMU-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Mus musculus 15379 R-MMU-9020261 https://reactome.org/PathwayBrowser/#/R-MMU-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Mus musculus 15379 R-MMU-9020264 https://reactome.org/PathwayBrowser/#/R-MMU-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Mus musculus 15379 R-MMU-9020274 https://reactome.org/PathwayBrowser/#/R-MMU-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Mus musculus 15379 R-MMU-9020275 https://reactome.org/PathwayBrowser/#/R-MMU-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Mus musculus 15379 R-MMU-9020282 https://reactome.org/PathwayBrowser/#/R-MMU-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Mus musculus 15379 R-MMU-9020610 https://reactome.org/PathwayBrowser/#/R-MMU-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Mus musculus 15379 R-MMU-9024872 https://reactome.org/PathwayBrowser/#/R-MMU-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Mus musculus 15379 R-MMU-9024997 https://reactome.org/PathwayBrowser/#/R-MMU-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Mus musculus 15379 R-MMU-9025152 https://reactome.org/PathwayBrowser/#/R-MMU-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Mus musculus 15379 R-MMU-9025957 https://reactome.org/PathwayBrowser/#/R-MMU-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Mus musculus 15379 R-MMU-9025996 https://reactome.org/PathwayBrowser/#/R-MMU-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Mus musculus 15379 R-MMU-9026003 https://reactome.org/PathwayBrowser/#/R-MMU-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Mus musculus 15379 R-MMU-9026005 https://reactome.org/PathwayBrowser/#/R-MMU-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Mus musculus 15379 R-MMU-9026006 https://reactome.org/PathwayBrowser/#/R-MMU-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Mus musculus 15379 R-MMU-9026405 https://reactome.org/PathwayBrowser/#/R-MMU-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Mus musculus 15379 R-MMU-9026408 https://reactome.org/PathwayBrowser/#/R-MMU-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Mus musculus 15379 R-MMU-9027043 https://reactome.org/PathwayBrowser/#/R-MMU-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Mus musculus 15379 R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 15379 R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 15379 R-MMU-9027532 https://reactome.org/PathwayBrowser/#/R-MMU-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Mus musculus 15379 R-MMU-9027607 https://reactome.org/PathwayBrowser/#/R-MMU-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Mus musculus 15379 R-MMU-9027624 https://reactome.org/PathwayBrowser/#/R-MMU-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Mus musculus 15379 R-MMU-9027627 https://reactome.org/PathwayBrowser/#/R-MMU-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Mus musculus 15379 R-MMU-9027628 https://reactome.org/PathwayBrowser/#/R-MMU-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Mus musculus 15379 R-MMU-9027633 https://reactome.org/PathwayBrowser/#/R-MMU-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Mus musculus 15379 R-MMU-9028255 https://reactome.org/PathwayBrowser/#/R-MMU-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Mus musculus 15379 R-MMU-9037761 https://reactome.org/PathwayBrowser/#/R-MMU-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Mus musculus 15379 R-MMU-917891 https://reactome.org/PathwayBrowser/#/R-MMU-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Mus musculus 15379 R-MMU-917933 https://reactome.org/PathwayBrowser/#/R-MMU-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Mus musculus 15379 R-MMU-9629578 https://reactome.org/PathwayBrowser/#/R-MMU-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Mus musculus 15379 R-MMU-9629591 https://reactome.org/PathwayBrowser/#/R-MMU-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Mus musculus 15379 R-MMU-9629869 https://reactome.org/PathwayBrowser/#/R-MMU-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Mus musculus 15379 R-MMU-9629888 https://reactome.org/PathwayBrowser/#/R-MMU-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Mus musculus 15379 R-MMU-9629946 https://reactome.org/PathwayBrowser/#/R-MMU-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Mus musculus 15379 R-MMU-9630022 https://reactome.org/PathwayBrowser/#/R-MMU-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Mus musculus 15379 R-MMU-9630769 https://reactome.org/PathwayBrowser/#/R-MMU-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Mus musculus 15379 R-MMU-9630967 https://reactome.org/PathwayBrowser/#/R-MMU-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Mus musculus 15379 R-MMU-9630993 https://reactome.org/PathwayBrowser/#/R-MMU-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Mus musculus 15379 R-MMU-965019 https://reactome.org/PathwayBrowser/#/R-MMU-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Mus musculus 15379 R-MMU-965079 https://reactome.org/PathwayBrowser/#/R-MMU-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Mus musculus 15379 R-MMU-9709360 https://reactome.org/PathwayBrowser/#/R-MMU-9709360 H2O2 reduces MetHb IEA Mus musculus 15379 R-MMU-9749986 https://reactome.org/PathwayBrowser/#/R-MMU-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Mus musculus 15379 R-MMU-9750016 https://reactome.org/PathwayBrowser/#/R-MMU-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Mus musculus 15379 R-MMU-9753285 https://reactome.org/PathwayBrowser/#/R-MMU-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Mus musculus 15379 R-MMU-9756138 https://reactome.org/PathwayBrowser/#/R-MMU-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Mus musculus 15379 R-MMU-9756162 https://reactome.org/PathwayBrowser/#/R-MMU-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Mus musculus 15379 R-MMU-9756169 https://reactome.org/PathwayBrowser/#/R-MMU-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Mus musculus 15379 R-MMU-9756180 https://reactome.org/PathwayBrowser/#/R-MMU-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Mus musculus 15379 R-MMU-975635 https://reactome.org/PathwayBrowser/#/R-MMU-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Mus musculus 15379 R-MMU-9758674 https://reactome.org/PathwayBrowser/#/R-MMU-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Mus musculus 15379 R-MMU-9817463 https://reactome.org/PathwayBrowser/#/R-MMU-9817463 Tet3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 dimethylated on lysine-9 TAS Mus musculus 15379 R-MMU-9817575 https://reactome.org/PathwayBrowser/#/R-MMU-9817575 ERO1B oxidizes P4HB IEA Mus musculus 15379 R-MMU-9822448 https://reactome.org/PathwayBrowser/#/R-MMU-9822448 Kdm5b demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 15379 R-MMU-9822463 https://reactome.org/PathwayBrowser/#/R-MMU-9822463 Kdm5a demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 15379 R-MMU-9822924 https://reactome.org/PathwayBrowser/#/R-MMU-9822924 Kdm6b (Jmjd3) demethylates histone H3 trimethyllysine-27 (H3K27me3) TAS Mus musculus 15379 R-MMU-9822964 https://reactome.org/PathwayBrowser/#/R-MMU-9822964 Kdm6a (Utx) demethylates trimethylated histone H3 lysine-27 (H3K27me3) TAS Mus musculus 15379 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 15379 R-PFA-189421 https://reactome.org/PathwayBrowser/#/R-PFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Plasmodium falciparum 15379 R-PFA-189423 https://reactome.org/PathwayBrowser/#/R-PFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Plasmodium falciparum 15379 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 15379 R-PFA-204662 https://reactome.org/PathwayBrowser/#/R-PFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Plasmodium falciparum 15379 R-PFA-2160492 https://reactome.org/PathwayBrowser/#/R-PFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Plasmodium falciparum 15379 R-PFA-2172678 https://reactome.org/PathwayBrowser/#/R-PFA-2172678 PHF8 demethylates histone H4K20me1 IEA Plasmodium falciparum 15379 R-PFA-3341294 https://reactome.org/PathwayBrowser/#/R-PFA-3341294 Superoxide reduces cytochrome c IEA Plasmodium falciparum 15379 R-PFA-418436 https://reactome.org/PathwayBrowser/#/R-PFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Plasmodium falciparum 15379 R-PFA-4724284 https://reactome.org/PathwayBrowser/#/R-PFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Plasmodium falciparum 15379 R-PFA-5661115 https://reactome.org/PathwayBrowser/#/R-PFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Plasmodium falciparum 15379 R-PFA-5690565 https://reactome.org/PathwayBrowser/#/R-PFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15379 R-PFA-8847579 https://reactome.org/PathwayBrowser/#/R-PFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15379 R-PFA-9817575 https://reactome.org/PathwayBrowser/#/R-PFA-9817575 ERO1B oxidizes P4HB IEA Plasmodium falciparum 15379 R-RNO-1222376 https://reactome.org/PathwayBrowser/#/R-RNO-1222376 NOX2 generates superoxide from oxygen IEA Rattus norvegicus 15379 R-RNO-1234164 https://reactome.org/PathwayBrowser/#/R-RNO-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Rattus norvegicus 15379 R-RNO-1234165 https://reactome.org/PathwayBrowser/#/R-RNO-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 15379 R-RNO-1234173 https://reactome.org/PathwayBrowser/#/R-RNO-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 15379 R-RNO-1234177 https://reactome.org/PathwayBrowser/#/R-RNO-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 15379 R-RNO-1234181 https://reactome.org/PathwayBrowser/#/R-RNO-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 15379 R-RNO-1236967 https://reactome.org/PathwayBrowser/#/R-RNO-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Rattus norvegicus 15379 R-RNO-1237119 https://reactome.org/PathwayBrowser/#/R-RNO-1237119 Acireductone is oxidized to MOB IEA Rattus norvegicus 15379 R-RNO-1237325 https://reactome.org/PathwayBrowser/#/R-RNO-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Rattus norvegicus 15379 R-RNO-1247668 https://reactome.org/PathwayBrowser/#/R-RNO-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Rattus norvegicus 15379 R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 15379 R-RNO-140355 https://reactome.org/PathwayBrowser/#/R-RNO-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Rattus norvegicus 15379 R-RNO-141186 https://reactome.org/PathwayBrowser/#/R-RNO-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Rattus norvegicus 15379 R-RNO-141200 https://reactome.org/PathwayBrowser/#/R-RNO-141200 MAOB:FAD oxidatively deaminates of PEA IEA Rattus norvegicus 15379 R-RNO-141202 https://reactome.org/PathwayBrowser/#/R-RNO-141202 MAOB:FAD oxidatively deaminates TYR IEA Rattus norvegicus 15379 R-RNO-141341 https://reactome.org/PathwayBrowser/#/R-RNO-141341 SMOX-3 oxidises SPN to SPM IEA Rattus norvegicus 15379 R-RNO-141348 https://reactome.org/PathwayBrowser/#/R-RNO-141348 PAO:FAD oxidises NASPM to PTCN IEA Rattus norvegicus 15379 R-RNO-141351 https://reactome.org/PathwayBrowser/#/R-RNO-141351 PAOX:FAD oxidises NASPN to SPM IEA Rattus norvegicus 15379 R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 15379 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 15379 R-RNO-1562626 https://reactome.org/PathwayBrowser/#/R-RNO-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Rattus norvegicus 15379 R-RNO-156526 https://reactome.org/PathwayBrowser/#/R-RNO-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15379 R-RNO-159752 https://reactome.org/PathwayBrowser/#/R-RNO-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Rattus norvegicus 15379 R-RNO-159761 https://reactome.org/PathwayBrowser/#/R-RNO-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Rattus norvegicus 15379 R-RNO-159795 https://reactome.org/PathwayBrowser/#/R-RNO-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Rattus norvegicus 15379 R-RNO-159803 https://reactome.org/PathwayBrowser/#/R-RNO-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Rattus norvegicus 15379 R-RNO-159819 https://reactome.org/PathwayBrowser/#/R-RNO-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Rattus norvegicus 15379 R-RNO-159826 https://reactome.org/PathwayBrowser/#/R-RNO-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Rattus norvegicus 15379 R-RNO-1614544 https://reactome.org/PathwayBrowser/#/R-RNO-1614544 Sulfite is oxidized to sulfate IEA Rattus norvegicus 15379 R-RNO-1614605 https://reactome.org/PathwayBrowser/#/R-RNO-1614605 Persulfide sulfur is dioxygenated IEA Rattus norvegicus 15379 R-RNO-1614645 https://reactome.org/PathwayBrowser/#/R-RNO-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Rattus norvegicus 15379 R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 15379 R-RNO-163820 https://reactome.org/PathwayBrowser/#/R-RNO-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Rattus norvegicus 15379 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus 15379 R-RNO-1655453 https://reactome.org/PathwayBrowser/#/R-RNO-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Rattus norvegicus 15379 R-RNO-189398 https://reactome.org/PathwayBrowser/#/R-RNO-189398 HMOX1 dimer, HMOX2 cleave heme IEA Rattus norvegicus 15379 R-RNO-189421 https://reactome.org/PathwayBrowser/#/R-RNO-189421 CPO transforms COPRO3 to PPGEN9 IEA Rattus norvegicus 15379 R-RNO-189423 https://reactome.org/PathwayBrowser/#/R-RNO-189423 PPO oxidises PPGEN9 to PRIN9 IEA Rattus norvegicus 15379 R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 15379 R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 15379 R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 15379 R-RNO-191999 https://reactome.org/PathwayBrowser/#/R-RNO-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Rattus norvegicus 15379 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 15379 R-RNO-192054 https://reactome.org/PathwayBrowser/#/R-RNO-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Rattus norvegicus 15379 R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 15379 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 15379 R-RNO-192123 https://reactome.org/PathwayBrowser/#/R-RNO-192123 CYP27A1 27-hydroxylates CHOL IEA Rattus norvegicus 15379 R-RNO-192157 https://reactome.org/PathwayBrowser/#/R-RNO-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Rattus norvegicus 15379 R-RNO-192178 https://reactome.org/PathwayBrowser/#/R-RNO-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Rattus norvegicus 15379 R-RNO-192335 https://reactome.org/PathwayBrowser/#/R-RNO-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Rattus norvegicus 15379 R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 15379 R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 15379 R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 15379 R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 15379 R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 15379 R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 15379 R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 15379 R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 15379 R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 15379 R-RNO-193369 https://reactome.org/PathwayBrowser/#/R-RNO-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Rattus norvegicus 15379 R-RNO-193393 https://reactome.org/PathwayBrowser/#/R-RNO-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Rattus norvegicus 15379 R-RNO-193460 https://reactome.org/PathwayBrowser/#/R-RNO-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Rattus norvegicus 15379 R-RNO-193709 https://reactome.org/PathwayBrowser/#/R-RNO-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Rattus norvegicus 15379 R-RNO-193713 https://reactome.org/PathwayBrowser/#/R-RNO-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Rattus norvegicus 15379 R-RNO-193719 https://reactome.org/PathwayBrowser/#/R-RNO-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15379 R-RNO-193737 https://reactome.org/PathwayBrowser/#/R-RNO-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Rattus norvegicus 15379 R-RNO-193780 https://reactome.org/PathwayBrowser/#/R-RNO-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15379 R-RNO-193787 https://reactome.org/PathwayBrowser/#/R-RNO-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Rattus norvegicus 15379 R-RNO-193792 https://reactome.org/PathwayBrowser/#/R-RNO-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Rattus norvegicus 15379 R-RNO-193845 https://reactome.org/PathwayBrowser/#/R-RNO-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Rattus norvegicus 15379 R-RNO-193964 https://reactome.org/PathwayBrowser/#/R-RNO-193964 CYP21A2 21-hydroxylates PROG IEA Rattus norvegicus 15379 R-RNO-193965 https://reactome.org/PathwayBrowser/#/R-RNO-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Rattus norvegicus 15379 R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 15379 R-RNO-193995 https://reactome.org/PathwayBrowser/#/R-RNO-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Rattus norvegicus 15379 R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 15379 R-RNO-194017 https://reactome.org/PathwayBrowser/#/R-RNO-194017 CYP11B2 oxidises 11DCORST to CORST IEA Rattus norvegicus 15379 R-RNO-194641 https://reactome.org/PathwayBrowser/#/R-RNO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15379 R-RNO-194669 https://reactome.org/PathwayBrowser/#/R-RNO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15379 R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 15379 R-RNO-195664 https://reactome.org/PathwayBrowser/#/R-RNO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Rattus norvegicus 15379 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus 15379 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus 15379 R-RNO-198563 https://reactome.org/PathwayBrowser/#/R-RNO-198563 IDO1 dioxygenates L-Trp to NFK IEA Rattus norvegicus 15379 R-RNO-2002466 https://reactome.org/PathwayBrowser/#/R-RNO-2002466 Formation of allysine by LOX IEA Rattus norvegicus 15379 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 15379 R-RNO-2046084 https://reactome.org/PathwayBrowser/#/R-RNO-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Rattus norvegicus 15379 R-RNO-2046089 https://reactome.org/PathwayBrowser/#/R-RNO-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Rattus norvegicus 15379 R-RNO-2046091 https://reactome.org/PathwayBrowser/#/R-RNO-2046091 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA TAS Rattus norvegicus 15379 R-RNO-2046092 https://reactome.org/PathwayBrowser/#/R-RNO-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Rattus norvegicus 15379 R-RNO-2046096 https://reactome.org/PathwayBrowser/#/R-RNO-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Rattus norvegicus 15379 R-RNO-2046097 https://reactome.org/PathwayBrowser/#/R-RNO-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 15379 R-RNO-204662 https://reactome.org/PathwayBrowser/#/R-RNO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Rattus norvegicus 15379 R-RNO-2066787 https://reactome.org/PathwayBrowser/#/R-RNO-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Rattus norvegicus 15379 R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 15379 R-RNO-209823 https://reactome.org/PathwayBrowser/#/R-RNO-209823 Tyrosine is hydroxylated to dopa IEA Rattus norvegicus 15379 R-RNO-209828 https://reactome.org/PathwayBrowser/#/R-RNO-209828 Tryptophan is hydroxylated IEA Rattus norvegicus 15379 R-RNO-209845 https://reactome.org/PathwayBrowser/#/R-RNO-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Rattus norvegicus 15379 R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 15379 R-RNO-209891 https://reactome.org/PathwayBrowser/#/R-RNO-209891 Dopamine is oxidised to noradrenaline IEA Rattus norvegicus 15379 R-RNO-211873 https://reactome.org/PathwayBrowser/#/R-RNO-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Rattus norvegicus 15379 R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 15379 R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 15379 R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 15379 R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 15379 R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 15379 R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 15379 R-RNO-211923 https://reactome.org/PathwayBrowser/#/R-RNO-211923 CYP26C1 4-hydroxylates 9cRA IEA Rattus norvegicus 15379 R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 15379 R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 15379 R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 15379 R-RNO-211950 https://reactome.org/PathwayBrowser/#/R-RNO-211950 CYP24A1 24-hydroxylates CTL IEA Rattus norvegicus 15379 R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 15379 R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 15379 R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 15379 R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 15379 R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 15379 R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 15379 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 15379 R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 15379 R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 15379 R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 15379 R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 15379 R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 15379 R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15379 R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 15379 R-RNO-2160492 https://reactome.org/PathwayBrowser/#/R-RNO-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Rattus norvegicus 15379 R-RNO-2161745 https://reactome.org/PathwayBrowser/#/R-RNO-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15379 R-RNO-2161775 https://reactome.org/PathwayBrowser/#/R-RNO-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Rattus norvegicus 15379 R-RNO-2161792 https://reactome.org/PathwayBrowser/#/R-RNO-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15379 R-RNO-2161794 https://reactome.org/PathwayBrowser/#/R-RNO-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Rattus norvegicus 15379 R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Rattus norvegicus 15379 R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 15379 R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus 15379 R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Rattus norvegicus 15379 R-RNO-2161907 https://reactome.org/PathwayBrowser/#/R-RNO-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Rattus norvegicus 15379 R-RNO-2161917 https://reactome.org/PathwayBrowser/#/R-RNO-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Rattus norvegicus 15379 R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 15379 R-RNO-2161950 https://reactome.org/PathwayBrowser/#/R-RNO-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Rattus norvegicus 15379 R-RNO-2161951 https://reactome.org/PathwayBrowser/#/R-RNO-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Rattus norvegicus 15379 R-RNO-2161964 https://reactome.org/PathwayBrowser/#/R-RNO-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Rattus norvegicus 15379 R-RNO-2162002 https://reactome.org/PathwayBrowser/#/R-RNO-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Rattus norvegicus 15379 R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 15379 R-RNO-2168883 https://reactome.org/PathwayBrowser/#/R-RNO-2168883 Haptoglobin:Hemoglobin binds CD163 IEA Rattus norvegicus 15379 R-RNO-2168885 https://reactome.org/PathwayBrowser/#/R-RNO-2168885 Haptoglobin binds Hemoglobin IEA Rattus norvegicus 15379 R-RNO-2168889 https://reactome.org/PathwayBrowser/#/R-RNO-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Rattus norvegicus 15379 R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 15379 R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 15379 R-RNO-2172678 https://reactome.org/PathwayBrowser/#/R-RNO-2172678 PHF8 demethylates histone H4K20me1 IEA Rattus norvegicus 15379 R-RNO-2230938 https://reactome.org/PathwayBrowser/#/R-RNO-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Rattus norvegicus 15379 R-RNO-2309787 https://reactome.org/PathwayBrowser/#/R-RNO-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Rattus norvegicus 15379 R-RNO-2395340 https://reactome.org/PathwayBrowser/#/R-RNO-2395340 Formation of hydroxyallysine by LOX IEA Rattus norvegicus 15379 R-RNO-265296 https://reactome.org/PathwayBrowser/#/R-RNO-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Rattus norvegicus 15379 R-RNO-3204311 https://reactome.org/PathwayBrowser/#/R-RNO-3204311 AOX1 oxidises PXL to PDXate IEA Rattus norvegicus 15379 R-RNO-3299680 https://reactome.org/PathwayBrowser/#/R-RNO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Rattus norvegicus 15379 R-RNO-3299682 https://reactome.org/PathwayBrowser/#/R-RNO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Rattus norvegicus 15379 R-RNO-3299691 https://reactome.org/PathwayBrowser/#/R-RNO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Rattus norvegicus 15379 R-RNO-3341294 https://reactome.org/PathwayBrowser/#/R-RNO-3341294 Superoxide reduces cytochrome c IEA Rattus norvegicus 15379 R-RNO-374909 https://reactome.org/PathwayBrowser/#/R-RNO-374909 Catabolism of Noradrenaline IEA Rattus norvegicus 15379 R-RNO-3777112 https://reactome.org/PathwayBrowser/#/R-RNO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Rattus norvegicus 15379 R-RNO-379382 https://reactome.org/PathwayBrowser/#/R-RNO-379382 MAOA:FAD deaminates DA to DOPAC IEA Rattus norvegicus 15379 R-RNO-379395 https://reactome.org/PathwayBrowser/#/R-RNO-379395 MAOA:FAD deaminates 3MT to HVA IEA Rattus norvegicus 15379 R-RNO-389639 https://reactome.org/PathwayBrowser/#/R-RNO-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Rattus norvegicus 15379 R-RNO-389821 https://reactome.org/PathwayBrowser/#/R-RNO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Rattus norvegicus 15379 R-RNO-389842 https://reactome.org/PathwayBrowser/#/R-RNO-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Rattus norvegicus 15379 R-RNO-389862 https://reactome.org/PathwayBrowser/#/R-RNO-389862 Conversion of glyoxylate to oxalate IEA Rattus norvegicus 15379 R-RNO-389889 https://reactome.org/PathwayBrowser/#/R-RNO-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Rattus norvegicus 15379 R-RNO-389891 https://reactome.org/PathwayBrowser/#/R-RNO-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Rattus norvegicus 15379 R-RNO-390256 https://reactome.org/PathwayBrowser/#/R-RNO-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Rattus norvegicus 15379 R-RNO-418436 https://reactome.org/PathwayBrowser/#/R-RNO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Rattus norvegicus 15379 R-RNO-428259 https://reactome.org/PathwayBrowser/#/R-RNO-428259 DEGS1 dehydrogenates dihydroceramide IEA Rattus norvegicus 15379 R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 15379 R-RNO-4722133 https://reactome.org/PathwayBrowser/#/R-RNO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Rattus norvegicus 15379 R-RNO-4724279 https://reactome.org/PathwayBrowser/#/R-RNO-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Rattus norvegicus 15379 R-RNO-4724284 https://reactome.org/PathwayBrowser/#/R-RNO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Rattus norvegicus 15379 R-RNO-4754176 https://reactome.org/PathwayBrowser/#/R-RNO-4754176 JMJD6 demethylates MeR3-histone H3 IEA Rattus norvegicus 15379 R-RNO-4754181 https://reactome.org/PathwayBrowser/#/R-RNO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Rattus norvegicus 15379 R-RNO-4754187 https://reactome.org/PathwayBrowser/#/R-RNO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Rattus norvegicus 15379 R-RNO-5164399 https://reactome.org/PathwayBrowser/#/R-RNO-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Rattus norvegicus 15379 R-RNO-5218841 https://reactome.org/PathwayBrowser/#/R-RNO-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Rattus norvegicus 15379 R-RNO-5340214 https://reactome.org/PathwayBrowser/#/R-RNO-5340214 CYGB binds O2 IEA Rattus norvegicus 15379 R-RNO-5340226 https://reactome.org/PathwayBrowser/#/R-RNO-5340226 CYGB dioxygenates NO IEA Rattus norvegicus 15379 R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 15379 R-RNO-5423117 https://reactome.org/PathwayBrowser/#/R-RNO-5423117 PHF8 demethylates MeK21-histone H4 IEA Rattus norvegicus 15379 R-RNO-5423647 https://reactome.org/PathwayBrowser/#/R-RNO-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Rattus norvegicus 15379 R-RNO-5423664 https://reactome.org/PathwayBrowser/#/R-RNO-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Rattus norvegicus 15379 R-RNO-5423672 https://reactome.org/PathwayBrowser/#/R-RNO-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Rattus norvegicus 15379 R-RNO-5423678 https://reactome.org/PathwayBrowser/#/R-RNO-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Rattus norvegicus 15379 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 15379 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 15379 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 15379 R-RNO-5661114 https://reactome.org/PathwayBrowser/#/R-RNO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Rattus norvegicus 15379 R-RNO-5661115 https://reactome.org/PathwayBrowser/#/R-RNO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Rattus norvegicus 15379 R-RNO-5661116 https://reactome.org/PathwayBrowser/#/R-RNO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Rattus norvegicus 15379 R-RNO-5661120 https://reactome.org/PathwayBrowser/#/R-RNO-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Rattus norvegicus 15379 R-RNO-5661121 https://reactome.org/PathwayBrowser/#/R-RNO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Rattus norvegicus 15379 R-RNO-5661122 https://reactome.org/PathwayBrowser/#/R-RNO-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Rattus norvegicus 15379 R-RNO-5661124 https://reactome.org/PathwayBrowser/#/R-RNO-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Rattus norvegicus 15379 R-RNO-5661125 https://reactome.org/PathwayBrowser/#/R-RNO-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Rattus norvegicus 15379 R-RNO-5662692 https://reactome.org/PathwayBrowser/#/R-RNO-5662692 Dopa is oxidized to dopaquinone by TYR IEA Rattus norvegicus 15379 R-RNO-5668629 https://reactome.org/PathwayBrowser/#/R-RNO-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Rattus norvegicus 15379 R-RNO-5668718 https://reactome.org/PathwayBrowser/#/R-RNO-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 15379 R-RNO-5668731 https://reactome.org/PathwayBrowser/#/R-RNO-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 15379 R-RNO-5678327 https://reactome.org/PathwayBrowser/#/R-RNO-5678327 MIOX oxidises Ins to GlcA IEA Rattus norvegicus 15379 R-RNO-5690565 https://reactome.org/PathwayBrowser/#/R-RNO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Rattus norvegicus 15379 R-RNO-5691107 https://reactome.org/PathwayBrowser/#/R-RNO-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Rattus norvegicus 15379 R-RNO-5693681 https://reactome.org/PathwayBrowser/#/R-RNO-5693681 DUOX1,2 reduce O2 to H2O2 IEA Rattus norvegicus 15379 R-RNO-5693761 https://reactome.org/PathwayBrowser/#/R-RNO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Rattus norvegicus 15379 R-RNO-5696119 https://reactome.org/PathwayBrowser/#/R-RNO-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Rattus norvegicus 15379 R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 15379 R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 15379 R-RNO-6783880 https://reactome.org/PathwayBrowser/#/R-RNO-6783880 PIPOX oxidises PPCA to P6C IEA Rattus norvegicus 15379 R-RNO-6786239 https://reactome.org/PathwayBrowser/#/R-RNO-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Rattus norvegicus 15379 R-RNO-6787811 https://reactome.org/PathwayBrowser/#/R-RNO-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Rattus norvegicus 15379 R-RNO-6789092 https://reactome.org/PathwayBrowser/#/R-RNO-6789092 NOX2 generates superoxide anion from oxygen IEA Rattus norvegicus 15379 R-RNO-6807053 https://reactome.org/PathwayBrowser/#/R-RNO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Rattus norvegicus 15379 R-RNO-6807214 https://reactome.org/PathwayBrowser/#/R-RNO-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Rattus norvegicus 15379 R-RNO-6807557 https://reactome.org/PathwayBrowser/#/R-RNO-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Rattus norvegicus 15379 R-RNO-6810076 https://reactome.org/PathwayBrowser/#/R-RNO-6810076 DDO oxidizes D-Asp to OA IEA Rattus norvegicus 15379 R-RNO-6814153 https://reactome.org/PathwayBrowser/#/R-RNO-6814153 ADO oxidises 2AET to HTAU IEA Rattus norvegicus 15379 R-RNO-71118 https://reactome.org/PathwayBrowser/#/R-RNO-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Rattus norvegicus 15379 R-RNO-71163 https://reactome.org/PathwayBrowser/#/R-RNO-71163 HPD dioxygenates HPP IEA Rattus norvegicus 15379 R-RNO-71164 https://reactome.org/PathwayBrowser/#/R-RNO-71164 HGD dioxygenates homogentisate IEA Rattus norvegicus 15379 R-RNO-71188 https://reactome.org/PathwayBrowser/#/R-RNO-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Rattus norvegicus 15379 R-RNO-71200 https://reactome.org/PathwayBrowser/#/R-RNO-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Rattus norvegicus 15379 R-RNO-71218 https://reactome.org/PathwayBrowser/#/R-RNO-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Rattus norvegicus 15379 R-RNO-71241 https://reactome.org/PathwayBrowser/#/R-RNO-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Rattus norvegicus 15379 R-RNO-71261 https://reactome.org/PathwayBrowser/#/R-RNO-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Rattus norvegicus 15379 R-RNO-74247 https://reactome.org/PathwayBrowser/#/R-RNO-74247 XDH oxidizes hypoxanthine to form xanthine IEA Rattus norvegicus 15379 R-RNO-74258 https://reactome.org/PathwayBrowser/#/R-RNO-74258 XDH oxidizes xanthine to form urate IEA Rattus norvegicus 15379 R-RNO-76031 https://reactome.org/PathwayBrowser/#/R-RNO-76031 2 H2O2 => O2 + 2 H2O IEA Rattus norvegicus 15379 R-RNO-76354 https://reactome.org/PathwayBrowser/#/R-RNO-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Rattus norvegicus 15379 R-RNO-76373 https://reactome.org/PathwayBrowser/#/R-RNO-76373 N-hydroxylation of 4-aminobiphenyl IEA Rattus norvegicus 15379 R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 15379 R-RNO-76397 https://reactome.org/PathwayBrowser/#/R-RNO-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Rattus norvegicus 15379 R-RNO-76416 https://reactome.org/PathwayBrowser/#/R-RNO-76416 Benzene is hydroxylated to phenol IEA Rattus norvegicus 15379 R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 15379 R-RNO-76453 https://reactome.org/PathwayBrowser/#/R-RNO-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Rattus norvegicus 15379 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 15379 R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 15379 R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 15379 R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 15379 R-RNO-8878581 https://reactome.org/PathwayBrowser/#/R-RNO-8878581 TYRP1 oxidises DHICA to IQCA IEA Rattus norvegicus 15379 R-RNO-888614 https://reactome.org/PathwayBrowser/#/R-RNO-888614 IDO2 dioxygenates L-Trp to NFK IEA Rattus norvegicus 15379 R-RNO-8953398 https://reactome.org/PathwayBrowser/#/R-RNO-8953398 PIR oxygenates quercetin IEA Rattus norvegicus 15379 R-RNO-8956458 https://reactome.org/PathwayBrowser/#/R-RNO-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Rattus norvegicus 15379 R-RNO-8981606 https://reactome.org/PathwayBrowser/#/R-RNO-8981606 Myoglobin binds oxygen IEA Rattus norvegicus 15379 R-RNO-8981610 https://reactome.org/PathwayBrowser/#/R-RNO-8981610 Neuroglobin binds oxygen IEA Rattus norvegicus 15379 R-RNO-8981621 https://reactome.org/PathwayBrowser/#/R-RNO-8981621 Neuroglobin:oxygen dissociates IEA Rattus norvegicus 15379 R-RNO-8981622 https://reactome.org/PathwayBrowser/#/R-RNO-8981622 Myoglobin:oxygen dissociates IEA Rattus norvegicus 15379 R-RNO-8982617 https://reactome.org/PathwayBrowser/#/R-RNO-8982617 CYGB:O2 dissociates IEA Rattus norvegicus 15379 R-RNO-9018858 https://reactome.org/PathwayBrowser/#/R-RNO-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Rattus norvegicus 15379 R-RNO-9018859 https://reactome.org/PathwayBrowser/#/R-RNO-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Rattus norvegicus 15379 R-RNO-9018863 https://reactome.org/PathwayBrowser/#/R-RNO-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Rattus norvegicus 15379 R-RNO-9018880 https://reactome.org/PathwayBrowser/#/R-RNO-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Rattus norvegicus 15379 R-RNO-9018894 https://reactome.org/PathwayBrowser/#/R-RNO-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Rattus norvegicus 15379 R-RNO-9018907 https://reactome.org/PathwayBrowser/#/R-RNO-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Rattus norvegicus 15379 R-RNO-9020251 https://reactome.org/PathwayBrowser/#/R-RNO-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Rattus norvegicus 15379 R-RNO-9020259 https://reactome.org/PathwayBrowser/#/R-RNO-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Rattus norvegicus 15379 R-RNO-9020261 https://reactome.org/PathwayBrowser/#/R-RNO-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Rattus norvegicus 15379 R-RNO-9020264 https://reactome.org/PathwayBrowser/#/R-RNO-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Rattus norvegicus 15379 R-RNO-9020274 https://reactome.org/PathwayBrowser/#/R-RNO-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Rattus norvegicus 15379 R-RNO-9020275 https://reactome.org/PathwayBrowser/#/R-RNO-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Rattus norvegicus 15379 R-RNO-9020282 https://reactome.org/PathwayBrowser/#/R-RNO-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Rattus norvegicus 15379 R-RNO-9020610 https://reactome.org/PathwayBrowser/#/R-RNO-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Rattus norvegicus 15379 R-RNO-9024872 https://reactome.org/PathwayBrowser/#/R-RNO-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Rattus norvegicus 15379 R-RNO-9024997 https://reactome.org/PathwayBrowser/#/R-RNO-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Rattus norvegicus 15379 R-RNO-9025152 https://reactome.org/PathwayBrowser/#/R-RNO-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Rattus norvegicus 15379 R-RNO-9025957 https://reactome.org/PathwayBrowser/#/R-RNO-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Rattus norvegicus 15379 R-RNO-9025996 https://reactome.org/PathwayBrowser/#/R-RNO-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Rattus norvegicus 15379 R-RNO-9026003 https://reactome.org/PathwayBrowser/#/R-RNO-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Rattus norvegicus 15379 R-RNO-9026005 https://reactome.org/PathwayBrowser/#/R-RNO-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Rattus norvegicus 15379 R-RNO-9026006 https://reactome.org/PathwayBrowser/#/R-RNO-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Rattus norvegicus 15379 R-RNO-9026405 https://reactome.org/PathwayBrowser/#/R-RNO-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Rattus norvegicus 15379 R-RNO-9026408 https://reactome.org/PathwayBrowser/#/R-RNO-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Rattus norvegicus 15379 R-RNO-9027043 https://reactome.org/PathwayBrowser/#/R-RNO-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Rattus norvegicus 15379 R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 15379 R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 15379 R-RNO-9027532 https://reactome.org/PathwayBrowser/#/R-RNO-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Rattus norvegicus 15379 R-RNO-9027607 https://reactome.org/PathwayBrowser/#/R-RNO-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Rattus norvegicus 15379 R-RNO-9027624 https://reactome.org/PathwayBrowser/#/R-RNO-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Rattus norvegicus 15379 R-RNO-9027627 https://reactome.org/PathwayBrowser/#/R-RNO-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Rattus norvegicus 15379 R-RNO-9027628 https://reactome.org/PathwayBrowser/#/R-RNO-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Rattus norvegicus 15379 R-RNO-9027633 https://reactome.org/PathwayBrowser/#/R-RNO-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Rattus norvegicus 15379 R-RNO-9028255 https://reactome.org/PathwayBrowser/#/R-RNO-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Rattus norvegicus 15379 R-RNO-9037761 https://reactome.org/PathwayBrowser/#/R-RNO-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Rattus norvegicus 15379 R-RNO-917891 https://reactome.org/PathwayBrowser/#/R-RNO-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Rattus norvegicus 15379 R-RNO-917933 https://reactome.org/PathwayBrowser/#/R-RNO-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Rattus norvegicus 15379 R-RNO-9629578 https://reactome.org/PathwayBrowser/#/R-RNO-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Rattus norvegicus 15379 R-RNO-9629591 https://reactome.org/PathwayBrowser/#/R-RNO-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Rattus norvegicus 15379 R-RNO-9629869 https://reactome.org/PathwayBrowser/#/R-RNO-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Rattus norvegicus 15379 R-RNO-9629888 https://reactome.org/PathwayBrowser/#/R-RNO-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Rattus norvegicus 15379 R-RNO-9629946 https://reactome.org/PathwayBrowser/#/R-RNO-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Rattus norvegicus 15379 R-RNO-9630022 https://reactome.org/PathwayBrowser/#/R-RNO-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Rattus norvegicus 15379 R-RNO-9630769 https://reactome.org/PathwayBrowser/#/R-RNO-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Rattus norvegicus 15379 R-RNO-9630967 https://reactome.org/PathwayBrowser/#/R-RNO-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Rattus norvegicus 15379 R-RNO-9630993 https://reactome.org/PathwayBrowser/#/R-RNO-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Rattus norvegicus 15379 R-RNO-965019 https://reactome.org/PathwayBrowser/#/R-RNO-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Rattus norvegicus 15379 R-RNO-965079 https://reactome.org/PathwayBrowser/#/R-RNO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Rattus norvegicus 15379 R-RNO-9709360 https://reactome.org/PathwayBrowser/#/R-RNO-9709360 H2O2 reduces MetHb IEA Rattus norvegicus 15379 R-RNO-9749986 https://reactome.org/PathwayBrowser/#/R-RNO-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Rattus norvegicus 15379 R-RNO-9750016 https://reactome.org/PathwayBrowser/#/R-RNO-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Rattus norvegicus 15379 R-RNO-9753285 https://reactome.org/PathwayBrowser/#/R-RNO-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Rattus norvegicus 15379 R-RNO-9756138 https://reactome.org/PathwayBrowser/#/R-RNO-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Rattus norvegicus 15379 R-RNO-9756162 https://reactome.org/PathwayBrowser/#/R-RNO-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Rattus norvegicus 15379 R-RNO-9756169 https://reactome.org/PathwayBrowser/#/R-RNO-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Rattus norvegicus 15379 R-RNO-9756180 https://reactome.org/PathwayBrowser/#/R-RNO-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Rattus norvegicus 15379 R-RNO-975635 https://reactome.org/PathwayBrowser/#/R-RNO-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Rattus norvegicus 15379 R-RNO-9758674 https://reactome.org/PathwayBrowser/#/R-RNO-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Rattus norvegicus 15379 R-RNO-9817575 https://reactome.org/PathwayBrowser/#/R-RNO-9817575 ERO1B oxidizes P4HB IEA Rattus norvegicus 15379 R-SCE-1237119 https://reactome.org/PathwayBrowser/#/R-SCE-1237119 Acireductone is oxidized to MOB IEA Saccharomyces cerevisiae 15379 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 15379 R-SCE-189421 https://reactome.org/PathwayBrowser/#/R-SCE-189421 CPO transforms COPRO3 to PPGEN9 IEA Saccharomyces cerevisiae 15379 R-SCE-189423 https://reactome.org/PathwayBrowser/#/R-SCE-189423 PPO oxidises PPGEN9 to PRIN9 IEA Saccharomyces cerevisiae 15379 R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 15379 R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 15379 R-SCE-194641 https://reactome.org/PathwayBrowser/#/R-SCE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 15379 R-SCE-194669 https://reactome.org/PathwayBrowser/#/R-SCE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 15379 R-SCE-194678 https://reactome.org/PathwayBrowser/#/R-SCE-194678 CYP51A1 demethylates LNSOL IEA Saccharomyces cerevisiae 15379 R-SCE-195664 https://reactome.org/PathwayBrowser/#/R-SCE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Saccharomyces cerevisiae 15379 R-SCE-198563 https://reactome.org/PathwayBrowser/#/R-SCE-198563 IDO1 dioxygenates L-Trp to NFK IEA Saccharomyces cerevisiae 15379 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 15379 R-SCE-204662 https://reactome.org/PathwayBrowser/#/R-SCE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Saccharomyces cerevisiae 15379 R-SCE-2162194 https://reactome.org/PathwayBrowser/#/R-SCE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Saccharomyces cerevisiae 15379 R-SCE-2162292 https://reactome.org/PathwayBrowser/#/R-SCE-2162292 HHB is hydroxylated to DHHB by Coq6 TAS Saccharomyces cerevisiae 15379 R-SCE-2164813 https://reactome.org/PathwayBrowser/#/R-SCE-2164813 HMPhOH is hydroxylated to MDMQ6H2 by HMPhOH monooxygenase TAS Saccharomyces cerevisiae 15379 R-SCE-2172678 https://reactome.org/PathwayBrowser/#/R-SCE-2172678 PHF8 demethylates histone H4K20me1 IEA Saccharomyces cerevisiae 15379 R-SCE-3299680 https://reactome.org/PathwayBrowser/#/R-SCE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Saccharomyces cerevisiae 15379 R-SCE-3299682 https://reactome.org/PathwayBrowser/#/R-SCE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Saccharomyces cerevisiae 15379 R-SCE-3299691 https://reactome.org/PathwayBrowser/#/R-SCE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Saccharomyces cerevisiae 15379 R-SCE-3341294 https://reactome.org/PathwayBrowser/#/R-SCE-3341294 Superoxide reduces cytochrome c IEA Saccharomyces cerevisiae 15379 R-SCE-3777112 https://reactome.org/PathwayBrowser/#/R-SCE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Saccharomyces cerevisiae 15379 R-SCE-389639 https://reactome.org/PathwayBrowser/#/R-SCE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Saccharomyces cerevisiae 15379 R-SCE-389891 https://reactome.org/PathwayBrowser/#/R-SCE-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Saccharomyces cerevisiae 15379 R-SCE-418436 https://reactome.org/PathwayBrowser/#/R-SCE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Saccharomyces cerevisiae 15379 R-SCE-4722133 https://reactome.org/PathwayBrowser/#/R-SCE-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Saccharomyces cerevisiae 15379 R-SCE-4724279 https://reactome.org/PathwayBrowser/#/R-SCE-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Saccharomyces cerevisiae 15379 R-SCE-4754181 https://reactome.org/PathwayBrowser/#/R-SCE-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Saccharomyces cerevisiae 15379 R-SCE-4754187 https://reactome.org/PathwayBrowser/#/R-SCE-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Saccharomyces cerevisiae 15379 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 15379 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 15379 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 15379 R-SCE-5661114 https://reactome.org/PathwayBrowser/#/R-SCE-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Saccharomyces cerevisiae 15379 R-SCE-5661116 https://reactome.org/PathwayBrowser/#/R-SCE-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Saccharomyces cerevisiae 15379 R-SCE-5661120 https://reactome.org/PathwayBrowser/#/R-SCE-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Saccharomyces cerevisiae 15379 R-SCE-5661121 https://reactome.org/PathwayBrowser/#/R-SCE-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Saccharomyces cerevisiae 15379 R-SCE-5690565 https://reactome.org/PathwayBrowser/#/R-SCE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15379 R-SCE-5693681 https://reactome.org/PathwayBrowser/#/R-SCE-5693681 DUOX1,2 reduce O2 to H2O2 IEA Saccharomyces cerevisiae 15379 R-SCE-5693761 https://reactome.org/PathwayBrowser/#/R-SCE-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Saccharomyces cerevisiae 15379 R-SCE-6807053 https://reactome.org/PathwayBrowser/#/R-SCE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Saccharomyces cerevisiae 15379 R-SCE-6807557 https://reactome.org/PathwayBrowser/#/R-SCE-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Saccharomyces cerevisiae 15379 R-SCE-71200 https://reactome.org/PathwayBrowser/#/R-SCE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Saccharomyces cerevisiae 15379 R-SCE-71218 https://reactome.org/PathwayBrowser/#/R-SCE-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Saccharomyces cerevisiae 15379 R-SCE-71261 https://reactome.org/PathwayBrowser/#/R-SCE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Saccharomyces cerevisiae 15379 R-SCE-76031 https://reactome.org/PathwayBrowser/#/R-SCE-76031 2 H2O2 => O2 + 2 H2O IEA Saccharomyces cerevisiae 15379 R-SCE-8847579 https://reactome.org/PathwayBrowser/#/R-SCE-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15379 R-SCE-888614 https://reactome.org/PathwayBrowser/#/R-SCE-888614 IDO2 dioxygenates L-Trp to NFK IEA Saccharomyces cerevisiae 15379 R-SCE-9630769 https://reactome.org/PathwayBrowser/#/R-SCE-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Saccharomyces cerevisiae 15379 R-SCE-965019 https://reactome.org/PathwayBrowser/#/R-SCE-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Saccharomyces cerevisiae 15379 R-SCE-965079 https://reactome.org/PathwayBrowser/#/R-SCE-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Saccharomyces cerevisiae 15379 R-SPO-1237119 https://reactome.org/PathwayBrowser/#/R-SPO-1237119 Acireductone is oxidized to MOB IEA Schizosaccharomyces pombe 15379 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 15379 R-SPO-189421 https://reactome.org/PathwayBrowser/#/R-SPO-189421 CPO transforms COPRO3 to PPGEN9 IEA Schizosaccharomyces pombe 15379 R-SPO-189423 https://reactome.org/PathwayBrowser/#/R-SPO-189423 PPO oxidises PPGEN9 to PRIN9 IEA Schizosaccharomyces pombe 15379 R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 15379 R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 15379 R-SPO-194641 https://reactome.org/PathwayBrowser/#/R-SPO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 15379 R-SPO-194669 https://reactome.org/PathwayBrowser/#/R-SPO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 15379 R-SPO-194678 https://reactome.org/PathwayBrowser/#/R-SPO-194678 CYP51A1 demethylates LNSOL IEA Schizosaccharomyces pombe 15379 R-SPO-195664 https://reactome.org/PathwayBrowser/#/R-SPO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Schizosaccharomyces pombe 15379 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 15379 R-SPO-204662 https://reactome.org/PathwayBrowser/#/R-SPO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Schizosaccharomyces pombe 15379 R-SPO-2162194 https://reactome.org/PathwayBrowser/#/R-SPO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Schizosaccharomyces pombe 15379 R-SPO-2172678 https://reactome.org/PathwayBrowser/#/R-SPO-2172678 PHF8 demethylates histone H4K20me1 IEA Schizosaccharomyces pombe 15379 R-SPO-3299680 https://reactome.org/PathwayBrowser/#/R-SPO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Schizosaccharomyces pombe 15379 R-SPO-3299682 https://reactome.org/PathwayBrowser/#/R-SPO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Schizosaccharomyces pombe 15379 R-SPO-3299691 https://reactome.org/PathwayBrowser/#/R-SPO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Schizosaccharomyces pombe 15379 R-SPO-3341294 https://reactome.org/PathwayBrowser/#/R-SPO-3341294 Superoxide reduces cytochrome c IEA Schizosaccharomyces pombe 15379 R-SPO-3777112 https://reactome.org/PathwayBrowser/#/R-SPO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Schizosaccharomyces pombe 15379 R-SPO-389821 https://reactome.org/PathwayBrowser/#/R-SPO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Schizosaccharomyces pombe 15379 R-SPO-418436 https://reactome.org/PathwayBrowser/#/R-SPO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Schizosaccharomyces pombe 15379 R-SPO-428259 https://reactome.org/PathwayBrowser/#/R-SPO-428259 DEGS1 dehydrogenates dihydroceramide IEA Schizosaccharomyces pombe 15379 R-SPO-428260 https://reactome.org/PathwayBrowser/#/R-SPO-428260 DEGS2 oxygenates dihydroceramide IEA Schizosaccharomyces pombe 15379 R-SPO-4722133 https://reactome.org/PathwayBrowser/#/R-SPO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Schizosaccharomyces pombe 15379 R-SPO-4724284 https://reactome.org/PathwayBrowser/#/R-SPO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Schizosaccharomyces pombe 15379 R-SPO-4754181 https://reactome.org/PathwayBrowser/#/R-SPO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Schizosaccharomyces pombe 15379 R-SPO-4754187 https://reactome.org/PathwayBrowser/#/R-SPO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Schizosaccharomyces pombe 15379 R-SPO-5423117 https://reactome.org/PathwayBrowser/#/R-SPO-5423117 PHF8 demethylates MeK21-histone H4 IEA Schizosaccharomyces pombe 15379 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 15379 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 15379 R-SPO-5661114 https://reactome.org/PathwayBrowser/#/R-SPO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Schizosaccharomyces pombe 15379 R-SPO-5661115 https://reactome.org/PathwayBrowser/#/R-SPO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Schizosaccharomyces pombe 15379 R-SPO-5661116 https://reactome.org/PathwayBrowser/#/R-SPO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Schizosaccharomyces pombe 15379 R-SPO-5661121 https://reactome.org/PathwayBrowser/#/R-SPO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Schizosaccharomyces pombe 15379 R-SPO-5690565 https://reactome.org/PathwayBrowser/#/R-SPO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15379 R-SPO-5693761 https://reactome.org/PathwayBrowser/#/R-SPO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Schizosaccharomyces pombe 15379 R-SPO-6783880 https://reactome.org/PathwayBrowser/#/R-SPO-6783880 PIPOX oxidises PPCA to P6C IEA Schizosaccharomyces pombe 15379 R-SPO-6807053 https://reactome.org/PathwayBrowser/#/R-SPO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Schizosaccharomyces pombe 15379 R-SPO-6810076 https://reactome.org/PathwayBrowser/#/R-SPO-6810076 DDO oxidizes D-Asp to OA IEA Schizosaccharomyces pombe 15379 R-SPO-76031 https://reactome.org/PathwayBrowser/#/R-SPO-76031 2 H2O2 => O2 + 2 H2O IEA Schizosaccharomyces pombe 15379 R-SPO-8847579 https://reactome.org/PathwayBrowser/#/R-SPO-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15379 R-SPO-9629946 https://reactome.org/PathwayBrowser/#/R-SPO-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Schizosaccharomyces pombe 15379 R-SPO-9630769 https://reactome.org/PathwayBrowser/#/R-SPO-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Schizosaccharomyces pombe 15379 R-SPO-965019 https://reactome.org/PathwayBrowser/#/R-SPO-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Schizosaccharomyces pombe 15379 R-SPO-965079 https://reactome.org/PathwayBrowser/#/R-SPO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Schizosaccharomyces pombe 15379 R-SSC-1222376 https://reactome.org/PathwayBrowser/#/R-SSC-1222376 NOX2 generates superoxide from oxygen IEA Sus scrofa 15379 R-SSC-1234164 https://reactome.org/PathwayBrowser/#/R-SSC-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Sus scrofa 15379 R-SSC-1234165 https://reactome.org/PathwayBrowser/#/R-SSC-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 15379 R-SSC-1234173 https://reactome.org/PathwayBrowser/#/R-SSC-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 15379 R-SSC-1234177 https://reactome.org/PathwayBrowser/#/R-SSC-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 15379 R-SSC-1234181 https://reactome.org/PathwayBrowser/#/R-SSC-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 15379 R-SSC-1236967 https://reactome.org/PathwayBrowser/#/R-SSC-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Sus scrofa 15379 R-SSC-1237119 https://reactome.org/PathwayBrowser/#/R-SSC-1237119 Acireductone is oxidized to MOB IEA Sus scrofa 15379 R-SSC-1237325 https://reactome.org/PathwayBrowser/#/R-SSC-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Sus scrofa 15379 R-SSC-1247668 https://reactome.org/PathwayBrowser/#/R-SSC-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Sus scrofa 15379 R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 15379 R-SSC-140355 https://reactome.org/PathwayBrowser/#/R-SSC-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Sus scrofa 15379 R-SSC-141186 https://reactome.org/PathwayBrowser/#/R-SSC-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Sus scrofa 15379 R-SSC-141200 https://reactome.org/PathwayBrowser/#/R-SSC-141200 MAOB:FAD oxidatively deaminates of PEA IEA Sus scrofa 15379 R-SSC-141202 https://reactome.org/PathwayBrowser/#/R-SSC-141202 MAOB:FAD oxidatively deaminates TYR IEA Sus scrofa 15379 R-SSC-141341 https://reactome.org/PathwayBrowser/#/R-SSC-141341 SMOX-3 oxidises SPN to SPM IEA Sus scrofa 15379 R-SSC-141348 https://reactome.org/PathwayBrowser/#/R-SSC-141348 PAO:FAD oxidises NASPM to PTCN IEA Sus scrofa 15379 R-SSC-141351 https://reactome.org/PathwayBrowser/#/R-SSC-141351 PAOX:FAD oxidises NASPN to SPM IEA Sus scrofa 15379 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 15379 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 15379 R-SSC-1562626 https://reactome.org/PathwayBrowser/#/R-SSC-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Sus scrofa 15379 R-SSC-156526 https://reactome.org/PathwayBrowser/#/R-SSC-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Sus scrofa 15379 R-SSC-159752 https://reactome.org/PathwayBrowser/#/R-SSC-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Sus scrofa 15379 R-SSC-159761 https://reactome.org/PathwayBrowser/#/R-SSC-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Sus scrofa 15379 R-SSC-159795 https://reactome.org/PathwayBrowser/#/R-SSC-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Sus scrofa 15379 R-SSC-159803 https://reactome.org/PathwayBrowser/#/R-SSC-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Sus scrofa 15379 R-SSC-159819 https://reactome.org/PathwayBrowser/#/R-SSC-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Sus scrofa 15379 R-SSC-159826 https://reactome.org/PathwayBrowser/#/R-SSC-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Sus scrofa 15379 R-SSC-1614544 https://reactome.org/PathwayBrowser/#/R-SSC-1614544 Sulfite is oxidized to sulfate IEA Sus scrofa 15379 R-SSC-1614605 https://reactome.org/PathwayBrowser/#/R-SSC-1614605 Persulfide sulfur is dioxygenated IEA Sus scrofa 15379 R-SSC-1614645 https://reactome.org/PathwayBrowser/#/R-SSC-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Sus scrofa 15379 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa 15379 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa 15379 R-SSC-1655453 https://reactome.org/PathwayBrowser/#/R-SSC-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Sus scrofa 15379 R-SSC-189398 https://reactome.org/PathwayBrowser/#/R-SSC-189398 HMOX1 dimer, HMOX2 cleave heme IEA Sus scrofa 15379 R-SSC-189421 https://reactome.org/PathwayBrowser/#/R-SSC-189421 CPO transforms COPRO3 to PPGEN9 IEA Sus scrofa 15379 R-SSC-189423 https://reactome.org/PathwayBrowser/#/R-SSC-189423 PPO oxidises PPGEN9 to PRIN9 IEA Sus scrofa 15379 R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 15379 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 15379 R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 15379 R-SSC-191999 https://reactome.org/PathwayBrowser/#/R-SSC-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Sus scrofa 15379 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 15379 R-SSC-192054 https://reactome.org/PathwayBrowser/#/R-SSC-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Sus scrofa 15379 R-SSC-192061 https://reactome.org/PathwayBrowser/#/R-SSC-192061 CYP46A1 24-hydroxylates CHOL IEA Sus scrofa 15379 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 15379 R-SSC-192123 https://reactome.org/PathwayBrowser/#/R-SSC-192123 CYP27A1 27-hydroxylates CHOL IEA Sus scrofa 15379 R-SSC-192157 https://reactome.org/PathwayBrowser/#/R-SSC-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Sus scrofa 15379 R-SSC-192178 https://reactome.org/PathwayBrowser/#/R-SSC-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Sus scrofa 15379 R-SSC-192335 https://reactome.org/PathwayBrowser/#/R-SSC-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Sus scrofa 15379 R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 15379 R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 15379 R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 15379 R-SSC-193068 https://reactome.org/PathwayBrowser/#/R-SSC-193068 CYP17A1 17-hydroxylates PREG IEA Sus scrofa 15379 R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 15379 R-SSC-193072 https://reactome.org/PathwayBrowser/#/R-SSC-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Sus scrofa 15379 R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 15379 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 15379 R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 15379 R-SSC-193369 https://reactome.org/PathwayBrowser/#/R-SSC-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Sus scrofa 15379 R-SSC-193393 https://reactome.org/PathwayBrowser/#/R-SSC-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Sus scrofa 15379 R-SSC-193460 https://reactome.org/PathwayBrowser/#/R-SSC-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Sus scrofa 15379 R-SSC-193709 https://reactome.org/PathwayBrowser/#/R-SSC-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Sus scrofa 15379 R-SSC-193713 https://reactome.org/PathwayBrowser/#/R-SSC-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Sus scrofa 15379 R-SSC-193719 https://reactome.org/PathwayBrowser/#/R-SSC-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 15379 R-SSC-193737 https://reactome.org/PathwayBrowser/#/R-SSC-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Sus scrofa 15379 R-SSC-193780 https://reactome.org/PathwayBrowser/#/R-SSC-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Sus scrofa 15379 R-SSC-193787 https://reactome.org/PathwayBrowser/#/R-SSC-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Sus scrofa 15379 R-SSC-193792 https://reactome.org/PathwayBrowser/#/R-SSC-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Sus scrofa 15379 R-SSC-193845 https://reactome.org/PathwayBrowser/#/R-SSC-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Sus scrofa 15379 R-SSC-193964 https://reactome.org/PathwayBrowser/#/R-SSC-193964 CYP21A2 21-hydroxylates PROG IEA Sus scrofa 15379 R-SSC-193965 https://reactome.org/PathwayBrowser/#/R-SSC-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Sus scrofa 15379 R-SSC-193981 https://reactome.org/PathwayBrowser/#/R-SSC-193981 CYP21A2 oxidises 17HPROG IEA Sus scrofa 15379 R-SSC-193995 https://reactome.org/PathwayBrowser/#/R-SSC-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Sus scrofa 15379 R-SSC-193997 https://reactome.org/PathwayBrowser/#/R-SSC-193997 CYP11B1 oxidises 11DCORT IEA Sus scrofa 15379 R-SSC-194017 https://reactome.org/PathwayBrowser/#/R-SSC-194017 CYP11B2 oxidises 11DCORST to CORST IEA Sus scrofa 15379 R-SSC-194641 https://reactome.org/PathwayBrowser/#/R-SSC-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15379 R-SSC-194669 https://reactome.org/PathwayBrowser/#/R-SSC-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15379 R-SSC-194678 https://reactome.org/PathwayBrowser/#/R-SSC-194678 CYP51A1 demethylates LNSOL IEA Sus scrofa 15379 R-SSC-195664 https://reactome.org/PathwayBrowser/#/R-SSC-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Sus scrofa 15379 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa 15379 R-SSC-198563 https://reactome.org/PathwayBrowser/#/R-SSC-198563 IDO1 dioxygenates L-Trp to NFK IEA Sus scrofa 15379 R-SSC-2002466 https://reactome.org/PathwayBrowser/#/R-SSC-2002466 Formation of allysine by LOX IEA Sus scrofa 15379 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 15379 R-SSC-2046084 https://reactome.org/PathwayBrowser/#/R-SSC-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Sus scrofa 15379 R-SSC-2046089 https://reactome.org/PathwayBrowser/#/R-SSC-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Sus scrofa 15379 R-SSC-2046092 https://reactome.org/PathwayBrowser/#/R-SSC-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Sus scrofa 15379 R-SSC-2046096 https://reactome.org/PathwayBrowser/#/R-SSC-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Sus scrofa 15379 R-SSC-2046097 https://reactome.org/PathwayBrowser/#/R-SSC-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 15379 R-SSC-204662 https://reactome.org/PathwayBrowser/#/R-SSC-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Sus scrofa 15379 R-SSC-2066787 https://reactome.org/PathwayBrowser/#/R-SSC-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Sus scrofa 15379 R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 15379 R-SSC-209823 https://reactome.org/PathwayBrowser/#/R-SSC-209823 Tyrosine is hydroxylated to dopa IEA Sus scrofa 15379 R-SSC-209828 https://reactome.org/PathwayBrowser/#/R-SSC-209828 Tryptophan is hydroxylated IEA Sus scrofa 15379 R-SSC-209845 https://reactome.org/PathwayBrowser/#/R-SSC-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Sus scrofa 15379 R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 15379 R-SSC-209891 https://reactome.org/PathwayBrowser/#/R-SSC-209891 Dopamine is oxidised to noradrenaline IEA Sus scrofa 15379 R-SSC-211873 https://reactome.org/PathwayBrowser/#/R-SSC-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Sus scrofa 15379 R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 15379 R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa 15379 R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 15379 R-SSC-211904 https://reactome.org/PathwayBrowser/#/R-SSC-211904 CYP4F12 18-hydroxylates ARA IEA Sus scrofa 15379 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 15379 R-SSC-211919 https://reactome.org/PathwayBrowser/#/R-SSC-211919 CYP4F8 19-hydroxylates PGH2 IEA Sus scrofa 15379 R-SSC-211923 https://reactome.org/PathwayBrowser/#/R-SSC-211923 CYP26C1 4-hydroxylates 9cRA IEA Sus scrofa 15379 R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa 15379 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 15379 R-SSC-211948 https://reactome.org/PathwayBrowser/#/R-SSC-211948 CYP3A4 can N-demethylate loperamide IEA Sus scrofa 15379 R-SSC-211950 https://reactome.org/PathwayBrowser/#/R-SSC-211950 CYP24A1 24-hydroxylates CTL IEA Sus scrofa 15379 R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 15379 R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 15379 R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa 15379 R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa 15379 R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa 15379 R-SSC-211968 https://reactome.org/PathwayBrowser/#/R-SSC-211968 CYP2W1 oxidises INDOL IEA Sus scrofa 15379 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 15379 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 15379 R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa 15379 R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 15379 R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa 15379 R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 15379 R-SSC-213175 https://reactome.org/PathwayBrowser/#/R-SSC-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Sus scrofa 15379 R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa 15379 R-SSC-2160492 https://reactome.org/PathwayBrowser/#/R-SSC-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Sus scrofa 15379 R-SSC-2161745 https://reactome.org/PathwayBrowser/#/R-SSC-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Sus scrofa 15379 R-SSC-2161775 https://reactome.org/PathwayBrowser/#/R-SSC-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Sus scrofa 15379 R-SSC-2161792 https://reactome.org/PathwayBrowser/#/R-SSC-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Sus scrofa 15379 R-SSC-2161794 https://reactome.org/PathwayBrowser/#/R-SSC-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Sus scrofa 15379 R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Sus scrofa 15379 R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa 15379 R-SSC-2161890 https://reactome.org/PathwayBrowser/#/R-SSC-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Sus scrofa 15379 R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Sus scrofa 15379 R-SSC-2161907 https://reactome.org/PathwayBrowser/#/R-SSC-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Sus scrofa 15379 R-SSC-2161917 https://reactome.org/PathwayBrowser/#/R-SSC-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Sus scrofa 15379 R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa 15379 R-SSC-2161950 https://reactome.org/PathwayBrowser/#/R-SSC-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Sus scrofa 15379 R-SSC-2161951 https://reactome.org/PathwayBrowser/#/R-SSC-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Sus scrofa 15379 R-SSC-2161964 https://reactome.org/PathwayBrowser/#/R-SSC-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Sus scrofa 15379 R-SSC-2162002 https://reactome.org/PathwayBrowser/#/R-SSC-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Sus scrofa 15379 R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa 15379 R-SSC-2168883 https://reactome.org/PathwayBrowser/#/R-SSC-2168883 Haptoglobin:Hemoglobin binds CD163 IEA Sus scrofa 15379 R-SSC-2168885 https://reactome.org/PathwayBrowser/#/R-SSC-2168885 Haptoglobin binds Hemoglobin IEA Sus scrofa 15379 R-SSC-2168889 https://reactome.org/PathwayBrowser/#/R-SSC-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Sus scrofa 15379 R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 15379 R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 15379 R-SSC-2172678 https://reactome.org/PathwayBrowser/#/R-SSC-2172678 PHF8 demethylates histone H4K20me1 IEA Sus scrofa 15379 R-SSC-2230938 https://reactome.org/PathwayBrowser/#/R-SSC-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Sus scrofa 15379 R-SSC-2309787 https://reactome.org/PathwayBrowser/#/R-SSC-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Sus scrofa 15379 R-SSC-2395340 https://reactome.org/PathwayBrowser/#/R-SSC-2395340 Formation of hydroxyallysine by LOX IEA Sus scrofa 15379 R-SSC-265296 https://reactome.org/PathwayBrowser/#/R-SSC-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Sus scrofa 15379 R-SSC-3204311 https://reactome.org/PathwayBrowser/#/R-SSC-3204311 AOX1 oxidises PXL to PDXate IEA Sus scrofa 15379 R-SSC-3299680 https://reactome.org/PathwayBrowser/#/R-SSC-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Sus scrofa 15379 R-SSC-3299682 https://reactome.org/PathwayBrowser/#/R-SSC-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Sus scrofa 15379 R-SSC-3299691 https://reactome.org/PathwayBrowser/#/R-SSC-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Sus scrofa 15379 R-SSC-3341294 https://reactome.org/PathwayBrowser/#/R-SSC-3341294 Superoxide reduces cytochrome c IEA Sus scrofa 15379 R-SSC-374909 https://reactome.org/PathwayBrowser/#/R-SSC-374909 Catabolism of Noradrenaline IEA Sus scrofa 15379 R-SSC-3777112 https://reactome.org/PathwayBrowser/#/R-SSC-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Sus scrofa 15379 R-SSC-379382 https://reactome.org/PathwayBrowser/#/R-SSC-379382 MAOA:FAD deaminates DA to DOPAC IEA Sus scrofa 15379 R-SSC-379395 https://reactome.org/PathwayBrowser/#/R-SSC-379395 MAOA:FAD deaminates 3MT to HVA IEA Sus scrofa 15379 R-SSC-389639 https://reactome.org/PathwayBrowser/#/R-SSC-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Sus scrofa 15379 R-SSC-389821 https://reactome.org/PathwayBrowser/#/R-SSC-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Sus scrofa 15379 R-SSC-389842 https://reactome.org/PathwayBrowser/#/R-SSC-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Sus scrofa 15379 R-SSC-389862 https://reactome.org/PathwayBrowser/#/R-SSC-389862 Conversion of glyoxylate to oxalate IEA Sus scrofa 15379 R-SSC-389889 https://reactome.org/PathwayBrowser/#/R-SSC-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Sus scrofa 15379 R-SSC-389891 https://reactome.org/PathwayBrowser/#/R-SSC-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Sus scrofa 15379 R-SSC-390256 https://reactome.org/PathwayBrowser/#/R-SSC-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Sus scrofa 15379 R-SSC-418436 https://reactome.org/PathwayBrowser/#/R-SSC-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Sus scrofa 15379 R-SSC-428259 https://reactome.org/PathwayBrowser/#/R-SSC-428259 DEGS1 dehydrogenates dihydroceramide IEA Sus scrofa 15379 R-SSC-428260 https://reactome.org/PathwayBrowser/#/R-SSC-428260 DEGS2 oxygenates dihydroceramide IEA Sus scrofa 15379 R-SSC-4722133 https://reactome.org/PathwayBrowser/#/R-SSC-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Sus scrofa 15379 R-SSC-4724279 https://reactome.org/PathwayBrowser/#/R-SSC-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Sus scrofa 15379 R-SSC-4724284 https://reactome.org/PathwayBrowser/#/R-SSC-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Sus scrofa 15379 R-SSC-4754176 https://reactome.org/PathwayBrowser/#/R-SSC-4754176 JMJD6 demethylates MeR3-histone H3 IEA Sus scrofa 15379 R-SSC-4754181 https://reactome.org/PathwayBrowser/#/R-SSC-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Sus scrofa 15379 R-SSC-4754187 https://reactome.org/PathwayBrowser/#/R-SSC-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Sus scrofa 15379 R-SSC-5164399 https://reactome.org/PathwayBrowser/#/R-SSC-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Sus scrofa 15379 R-SSC-5218841 https://reactome.org/PathwayBrowser/#/R-SSC-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Sus scrofa 15379 R-SSC-5340214 https://reactome.org/PathwayBrowser/#/R-SSC-5340214 CYGB binds O2 IEA Sus scrofa 15379 R-SSC-5340226 https://reactome.org/PathwayBrowser/#/R-SSC-5340226 CYGB dioxygenates NO IEA Sus scrofa 15379 R-SSC-5362525 https://reactome.org/PathwayBrowser/#/R-SSC-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Sus scrofa 15379 R-SSC-5423117 https://reactome.org/PathwayBrowser/#/R-SSC-5423117 PHF8 demethylates MeK21-histone H4 IEA Sus scrofa 15379 R-SSC-5423647 https://reactome.org/PathwayBrowser/#/R-SSC-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Sus scrofa 15379 R-SSC-5423664 https://reactome.org/PathwayBrowser/#/R-SSC-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Sus scrofa 15379 R-SSC-5423672 https://reactome.org/PathwayBrowser/#/R-SSC-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Sus scrofa 15379 R-SSC-5423678 https://reactome.org/PathwayBrowser/#/R-SSC-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Sus scrofa 15379 R-SSC-5602295 https://reactome.org/PathwayBrowser/#/R-SSC-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Sus scrofa 15379 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 15379 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 15379 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 15379 R-SSC-5661114 https://reactome.org/PathwayBrowser/#/R-SSC-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Sus scrofa 15379 R-SSC-5661115 https://reactome.org/PathwayBrowser/#/R-SSC-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Sus scrofa 15379 R-SSC-5661116 https://reactome.org/PathwayBrowser/#/R-SSC-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Sus scrofa 15379 R-SSC-5661120 https://reactome.org/PathwayBrowser/#/R-SSC-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Sus scrofa 15379 R-SSC-5661121 https://reactome.org/PathwayBrowser/#/R-SSC-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Sus scrofa 15379 R-SSC-5661122 https://reactome.org/PathwayBrowser/#/R-SSC-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Sus scrofa 15379 R-SSC-5661124 https://reactome.org/PathwayBrowser/#/R-SSC-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Sus scrofa 15379 R-SSC-5661125 https://reactome.org/PathwayBrowser/#/R-SSC-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Sus scrofa 15379 R-SSC-5662692 https://reactome.org/PathwayBrowser/#/R-SSC-5662692 Dopa is oxidized to dopaquinone by TYR IEA Sus scrofa 15379 R-SSC-5668629 https://reactome.org/PathwayBrowser/#/R-SSC-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Sus scrofa 15379 R-SSC-5668718 https://reactome.org/PathwayBrowser/#/R-SSC-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 15379 R-SSC-5668731 https://reactome.org/PathwayBrowser/#/R-SSC-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 15379 R-SSC-5678327 https://reactome.org/PathwayBrowser/#/R-SSC-5678327 MIOX oxidises Ins to GlcA IEA Sus scrofa 15379 R-SSC-5690565 https://reactome.org/PathwayBrowser/#/R-SSC-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15379 R-SSC-5691107 https://reactome.org/PathwayBrowser/#/R-SSC-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Sus scrofa 15379 R-SSC-5693681 https://reactome.org/PathwayBrowser/#/R-SSC-5693681 DUOX1,2 reduce O2 to H2O2 IEA Sus scrofa 15379 R-SSC-5693761 https://reactome.org/PathwayBrowser/#/R-SSC-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Sus scrofa 15379 R-SSC-5696119 https://reactome.org/PathwayBrowser/#/R-SSC-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Sus scrofa 15379 R-SSC-5696131 https://reactome.org/PathwayBrowser/#/R-SSC-5696131 AOC1 deaminates Hist IEA Sus scrofa 15379 R-SSC-5696146 https://reactome.org/PathwayBrowser/#/R-SSC-5696146 AOC2 deaminates TYR IEA Sus scrofa 15379 R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa 15379 R-SSC-6783880 https://reactome.org/PathwayBrowser/#/R-SSC-6783880 PIPOX oxidises PPCA to P6C IEA Sus scrofa 15379 R-SSC-6786239 https://reactome.org/PathwayBrowser/#/R-SSC-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Sus scrofa 15379 R-SSC-6787811 https://reactome.org/PathwayBrowser/#/R-SSC-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Sus scrofa 15379 R-SSC-6789092 https://reactome.org/PathwayBrowser/#/R-SSC-6789092 NOX2 generates superoxide anion from oxygen IEA Sus scrofa 15379 R-SSC-6807053 https://reactome.org/PathwayBrowser/#/R-SSC-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Sus scrofa 15379 R-SSC-6807214 https://reactome.org/PathwayBrowser/#/R-SSC-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Sus scrofa 15379 R-SSC-6807557 https://reactome.org/PathwayBrowser/#/R-SSC-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Sus scrofa 15379 R-SSC-6810076 https://reactome.org/PathwayBrowser/#/R-SSC-6810076 DDO oxidizes D-Asp to OA IEA Sus scrofa 15379 R-SSC-6814153 https://reactome.org/PathwayBrowser/#/R-SSC-6814153 ADO oxidises 2AET to HTAU IEA Sus scrofa 15379 R-SSC-71118 https://reactome.org/PathwayBrowser/#/R-SSC-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Sus scrofa 15379 R-SSC-71163 https://reactome.org/PathwayBrowser/#/R-SSC-71163 HPD dioxygenates HPP IEA Sus scrofa 15379 R-SSC-71164 https://reactome.org/PathwayBrowser/#/R-SSC-71164 HGD dioxygenates homogentisate IEA Sus scrofa 15379 R-SSC-71188 https://reactome.org/PathwayBrowser/#/R-SSC-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Sus scrofa 15379 R-SSC-71200 https://reactome.org/PathwayBrowser/#/R-SSC-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Sus scrofa 15379 R-SSC-71218 https://reactome.org/PathwayBrowser/#/R-SSC-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Sus scrofa 15379 R-SSC-71241 https://reactome.org/PathwayBrowser/#/R-SSC-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Sus scrofa 15379 R-SSC-71261 https://reactome.org/PathwayBrowser/#/R-SSC-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Sus scrofa 15379 R-SSC-74247 https://reactome.org/PathwayBrowser/#/R-SSC-74247 XDH oxidizes hypoxanthine to form xanthine IEA Sus scrofa 15379 R-SSC-74258 https://reactome.org/PathwayBrowser/#/R-SSC-74258 XDH oxidizes xanthine to form urate IEA Sus scrofa 15379 R-SSC-76031 https://reactome.org/PathwayBrowser/#/R-SSC-76031 2 H2O2 => O2 + 2 H2O IEA Sus scrofa 15379 R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa 15379 R-SSC-76373 https://reactome.org/PathwayBrowser/#/R-SSC-76373 N-hydroxylation of 4-aminobiphenyl IEA Sus scrofa 15379 R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 15379 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa 15379 R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa 15379 R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 15379 R-SSC-76453 https://reactome.org/PathwayBrowser/#/R-SSC-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Sus scrofa 15379 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 15379 R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 15379 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 15379 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 15379 R-SSC-8847579 https://reactome.org/PathwayBrowser/#/R-SSC-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15379 R-SSC-8865107 https://reactome.org/PathwayBrowser/#/R-SSC-8865107 MICAL1 produces NADP+, H2O2 IEA Sus scrofa 15379 R-SSC-8878581 https://reactome.org/PathwayBrowser/#/R-SSC-8878581 TYRP1 oxidises DHICA to IQCA IEA Sus scrofa 15379 R-SSC-888614 https://reactome.org/PathwayBrowser/#/R-SSC-888614 IDO2 dioxygenates L-Trp to NFK IEA Sus scrofa 15379 R-SSC-8953398 https://reactome.org/PathwayBrowser/#/R-SSC-8953398 PIR oxygenates quercetin IEA Sus scrofa 15379 R-SSC-8956458 https://reactome.org/PathwayBrowser/#/R-SSC-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Sus scrofa 15379 R-SSC-8981606 https://reactome.org/PathwayBrowser/#/R-SSC-8981606 Myoglobin binds oxygen IEA Sus scrofa 15379 R-SSC-8981610 https://reactome.org/PathwayBrowser/#/R-SSC-8981610 Neuroglobin binds oxygen IEA Sus scrofa 15379 R-SSC-8981621 https://reactome.org/PathwayBrowser/#/R-SSC-8981621 Neuroglobin:oxygen dissociates IEA Sus scrofa 15379 R-SSC-8981622 https://reactome.org/PathwayBrowser/#/R-SSC-8981622 Myoglobin:oxygen dissociates IEA Sus scrofa 15379 R-SSC-8982617 https://reactome.org/PathwayBrowser/#/R-SSC-8982617 CYGB:O2 dissociates IEA Sus scrofa 15379 R-SSC-9018858 https://reactome.org/PathwayBrowser/#/R-SSC-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Sus scrofa 15379 R-SSC-9018859 https://reactome.org/PathwayBrowser/#/R-SSC-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Sus scrofa 15379 R-SSC-9018863 https://reactome.org/PathwayBrowser/#/R-SSC-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Sus scrofa 15379 R-SSC-9018880 https://reactome.org/PathwayBrowser/#/R-SSC-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Sus scrofa 15379 R-SSC-9018894 https://reactome.org/PathwayBrowser/#/R-SSC-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Sus scrofa 15379 R-SSC-9018907 https://reactome.org/PathwayBrowser/#/R-SSC-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Sus scrofa 15379 R-SSC-9020251 https://reactome.org/PathwayBrowser/#/R-SSC-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Sus scrofa 15379 R-SSC-9020259 https://reactome.org/PathwayBrowser/#/R-SSC-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Sus scrofa 15379 R-SSC-9020261 https://reactome.org/PathwayBrowser/#/R-SSC-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Sus scrofa 15379 R-SSC-9020264 https://reactome.org/PathwayBrowser/#/R-SSC-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Sus scrofa 15379 R-SSC-9020274 https://reactome.org/PathwayBrowser/#/R-SSC-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Sus scrofa 15379 R-SSC-9020275 https://reactome.org/PathwayBrowser/#/R-SSC-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Sus scrofa 15379 R-SSC-9020282 https://reactome.org/PathwayBrowser/#/R-SSC-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Sus scrofa 15379 R-SSC-9020610 https://reactome.org/PathwayBrowser/#/R-SSC-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Sus scrofa 15379 R-SSC-9024872 https://reactome.org/PathwayBrowser/#/R-SSC-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Sus scrofa 15379 R-SSC-9024997 https://reactome.org/PathwayBrowser/#/R-SSC-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Sus scrofa 15379 R-SSC-9025152 https://reactome.org/PathwayBrowser/#/R-SSC-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Sus scrofa 15379 R-SSC-9025957 https://reactome.org/PathwayBrowser/#/R-SSC-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Sus scrofa 15379 R-SSC-9025996 https://reactome.org/PathwayBrowser/#/R-SSC-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Sus scrofa 15379 R-SSC-9026003 https://reactome.org/PathwayBrowser/#/R-SSC-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Sus scrofa 15379 R-SSC-9026005 https://reactome.org/PathwayBrowser/#/R-SSC-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Sus scrofa 15379 R-SSC-9026006 https://reactome.org/PathwayBrowser/#/R-SSC-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Sus scrofa 15379 R-SSC-9026405 https://reactome.org/PathwayBrowser/#/R-SSC-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Sus scrofa 15379 R-SSC-9026408 https://reactome.org/PathwayBrowser/#/R-SSC-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Sus scrofa 15379 R-SSC-9027043 https://reactome.org/PathwayBrowser/#/R-SSC-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Sus scrofa 15379 R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 15379 R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 15379 R-SSC-9027532 https://reactome.org/PathwayBrowser/#/R-SSC-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Sus scrofa 15379 R-SSC-9027607 https://reactome.org/PathwayBrowser/#/R-SSC-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Sus scrofa 15379 R-SSC-9027624 https://reactome.org/PathwayBrowser/#/R-SSC-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Sus scrofa 15379 R-SSC-9027627 https://reactome.org/PathwayBrowser/#/R-SSC-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Sus scrofa 15379 R-SSC-9027628 https://reactome.org/PathwayBrowser/#/R-SSC-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Sus scrofa 15379 R-SSC-9027633 https://reactome.org/PathwayBrowser/#/R-SSC-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Sus scrofa 15379 R-SSC-9028255 https://reactome.org/PathwayBrowser/#/R-SSC-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Sus scrofa 15379 R-SSC-9037761 https://reactome.org/PathwayBrowser/#/R-SSC-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Sus scrofa 15379 R-SSC-917891 https://reactome.org/PathwayBrowser/#/R-SSC-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Sus scrofa 15379 R-SSC-917933 https://reactome.org/PathwayBrowser/#/R-SSC-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Sus scrofa 15379 R-SSC-9629578 https://reactome.org/PathwayBrowser/#/R-SSC-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Sus scrofa 15379 R-SSC-9629591 https://reactome.org/PathwayBrowser/#/R-SSC-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Sus scrofa 15379 R-SSC-9629869 https://reactome.org/PathwayBrowser/#/R-SSC-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Sus scrofa 15379 R-SSC-9629888 https://reactome.org/PathwayBrowser/#/R-SSC-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Sus scrofa 15379 R-SSC-9629946 https://reactome.org/PathwayBrowser/#/R-SSC-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Sus scrofa 15379 R-SSC-9630022 https://reactome.org/PathwayBrowser/#/R-SSC-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Sus scrofa 15379 R-SSC-9630769 https://reactome.org/PathwayBrowser/#/R-SSC-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Sus scrofa 15379 R-SSC-9630967 https://reactome.org/PathwayBrowser/#/R-SSC-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Sus scrofa 15379 R-SSC-9630993 https://reactome.org/PathwayBrowser/#/R-SSC-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Sus scrofa 15379 R-SSC-965019 https://reactome.org/PathwayBrowser/#/R-SSC-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Sus scrofa 15379 R-SSC-965079 https://reactome.org/PathwayBrowser/#/R-SSC-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Sus scrofa 15379 R-SSC-9709360 https://reactome.org/PathwayBrowser/#/R-SSC-9709360 H2O2 reduces MetHb IEA Sus scrofa 15379 R-SSC-9749986 https://reactome.org/PathwayBrowser/#/R-SSC-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Sus scrofa 15379 R-SSC-9750016 https://reactome.org/PathwayBrowser/#/R-SSC-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Sus scrofa 15379 R-SSC-9753285 https://reactome.org/PathwayBrowser/#/R-SSC-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Sus scrofa 15379 R-SSC-9756138 https://reactome.org/PathwayBrowser/#/R-SSC-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Sus scrofa 15379 R-SSC-9756162 https://reactome.org/PathwayBrowser/#/R-SSC-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Sus scrofa 15379 R-SSC-9756169 https://reactome.org/PathwayBrowser/#/R-SSC-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Sus scrofa 15379 R-SSC-9756180 https://reactome.org/PathwayBrowser/#/R-SSC-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Sus scrofa 15379 R-SSC-975635 https://reactome.org/PathwayBrowser/#/R-SSC-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Sus scrofa 15379 R-SSC-9758674 https://reactome.org/PathwayBrowser/#/R-SSC-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Sus scrofa 15379 R-SSC-9817575 https://reactome.org/PathwayBrowser/#/R-SSC-9817575 ERO1B oxidizes P4HB IEA Sus scrofa 15379 R-XTR-1222376 https://reactome.org/PathwayBrowser/#/R-XTR-1222376 NOX2 generates superoxide from oxygen IEA Xenopus tropicalis 15379 R-XTR-1234164 https://reactome.org/PathwayBrowser/#/R-XTR-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Xenopus tropicalis 15379 R-XTR-1234165 https://reactome.org/PathwayBrowser/#/R-XTR-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 15379 R-XTR-1234173 https://reactome.org/PathwayBrowser/#/R-XTR-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 15379 R-XTR-1234177 https://reactome.org/PathwayBrowser/#/R-XTR-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 15379 R-XTR-1234181 https://reactome.org/PathwayBrowser/#/R-XTR-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 15379 R-XTR-1236967 https://reactome.org/PathwayBrowser/#/R-XTR-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Xenopus tropicalis 15379 R-XTR-1237119 https://reactome.org/PathwayBrowser/#/R-XTR-1237119 Acireductone is oxidized to MOB IEA Xenopus tropicalis 15379 R-XTR-1237325 https://reactome.org/PathwayBrowser/#/R-XTR-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Xenopus tropicalis 15379 R-XTR-1247668 https://reactome.org/PathwayBrowser/#/R-XTR-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Xenopus tropicalis 15379 R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 15379 R-XTR-140355 https://reactome.org/PathwayBrowser/#/R-XTR-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Xenopus tropicalis 15379 R-XTR-141200 https://reactome.org/PathwayBrowser/#/R-XTR-141200 MAOB:FAD oxidatively deaminates of PEA IEA Xenopus tropicalis 15379 R-XTR-141202 https://reactome.org/PathwayBrowser/#/R-XTR-141202 MAOB:FAD oxidatively deaminates TYR IEA Xenopus tropicalis 15379 R-XTR-141341 https://reactome.org/PathwayBrowser/#/R-XTR-141341 SMOX-3 oxidises SPN to SPM IEA Xenopus tropicalis 15379 R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 15379 R-XTR-1562626 https://reactome.org/PathwayBrowser/#/R-XTR-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Xenopus tropicalis 15379 R-XTR-156526 https://reactome.org/PathwayBrowser/#/R-XTR-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 15379 R-XTR-159752 https://reactome.org/PathwayBrowser/#/R-XTR-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Xenopus tropicalis 15379 R-XTR-159761 https://reactome.org/PathwayBrowser/#/R-XTR-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Xenopus tropicalis 15379 R-XTR-159795 https://reactome.org/PathwayBrowser/#/R-XTR-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Xenopus tropicalis 15379 R-XTR-159803 https://reactome.org/PathwayBrowser/#/R-XTR-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Xenopus tropicalis 15379 R-XTR-159819 https://reactome.org/PathwayBrowser/#/R-XTR-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Xenopus tropicalis 15379 R-XTR-159826 https://reactome.org/PathwayBrowser/#/R-XTR-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Xenopus tropicalis 15379 R-XTR-1614544 https://reactome.org/PathwayBrowser/#/R-XTR-1614544 Sulfite is oxidized to sulfate IEA Xenopus tropicalis 15379 R-XTR-1614605 https://reactome.org/PathwayBrowser/#/R-XTR-1614605 Persulfide sulfur is dioxygenated IEA Xenopus tropicalis 15379 R-XTR-1614645 https://reactome.org/PathwayBrowser/#/R-XTR-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Xenopus tropicalis 15379 R-XTR-163214 https://reactome.org/PathwayBrowser/#/R-XTR-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Xenopus tropicalis 15379 R-XTR-163820 https://reactome.org/PathwayBrowser/#/R-XTR-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Xenopus tropicalis 15379 R-XTR-1650808 https://reactome.org/PathwayBrowser/#/R-XTR-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Xenopus tropicalis 15379 R-XTR-1655453 https://reactome.org/PathwayBrowser/#/R-XTR-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Xenopus tropicalis 15379 R-XTR-189398 https://reactome.org/PathwayBrowser/#/R-XTR-189398 HMOX1 dimer, HMOX2 cleave heme IEA Xenopus tropicalis 15379 R-XTR-189421 https://reactome.org/PathwayBrowser/#/R-XTR-189421 CPO transforms COPRO3 to PPGEN9 IEA Xenopus tropicalis 15379 R-XTR-189423 https://reactome.org/PathwayBrowser/#/R-XTR-189423 PPO oxidises PPGEN9 to PRIN9 IEA Xenopus tropicalis 15379 R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 15379 R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 15379 R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 15379 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 15379 R-XTR-192061 https://reactome.org/PathwayBrowser/#/R-XTR-192061 CYP46A1 24-hydroxylates CHOL IEA Xenopus tropicalis 15379 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 15379 R-XTR-192157 https://reactome.org/PathwayBrowser/#/R-XTR-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Xenopus tropicalis 15379 R-XTR-192178 https://reactome.org/PathwayBrowser/#/R-XTR-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Xenopus tropicalis 15379 R-XTR-192335 https://reactome.org/PathwayBrowser/#/R-XTR-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Xenopus tropicalis 15379 R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 15379 R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 15379 R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 15379 R-XTR-193068 https://reactome.org/PathwayBrowser/#/R-XTR-193068 CYP17A1 17-hydroxylates PREG IEA Xenopus tropicalis 15379 R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 15379 R-XTR-193072 https://reactome.org/PathwayBrowser/#/R-XTR-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Xenopus tropicalis 15379 R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 15379 R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 15379 R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 15379 R-XTR-193369 https://reactome.org/PathwayBrowser/#/R-XTR-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Xenopus tropicalis 15379 R-XTR-193709 https://reactome.org/PathwayBrowser/#/R-XTR-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Xenopus tropicalis 15379 R-XTR-193845 https://reactome.org/PathwayBrowser/#/R-XTR-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Xenopus tropicalis 15379 R-XTR-193965 https://reactome.org/PathwayBrowser/#/R-XTR-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Xenopus tropicalis 15379 R-XTR-193995 https://reactome.org/PathwayBrowser/#/R-XTR-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Xenopus tropicalis 15379 R-XTR-193997 https://reactome.org/PathwayBrowser/#/R-XTR-193997 CYP11B1 oxidises 11DCORT IEA Xenopus tropicalis 15379 R-XTR-194017 https://reactome.org/PathwayBrowser/#/R-XTR-194017 CYP11B2 oxidises 11DCORST to CORST IEA Xenopus tropicalis 15379 R-XTR-194641 https://reactome.org/PathwayBrowser/#/R-XTR-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 15379 R-XTR-194669 https://reactome.org/PathwayBrowser/#/R-XTR-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 15379 R-XTR-195664 https://reactome.org/PathwayBrowser/#/R-XTR-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Xenopus tropicalis 15379 R-XTR-1980233 https://reactome.org/PathwayBrowser/#/R-XTR-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Xenopus tropicalis 15379 R-XTR-1981104 https://reactome.org/PathwayBrowser/#/R-XTR-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Xenopus tropicalis 15379 R-XTR-2002466 https://reactome.org/PathwayBrowser/#/R-XTR-2002466 Formation of allysine by LOX IEA Xenopus tropicalis 15379 R-XTR-2046089 https://reactome.org/PathwayBrowser/#/R-XTR-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Xenopus tropicalis 15379 R-XTR-2046092 https://reactome.org/PathwayBrowser/#/R-XTR-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Xenopus tropicalis 15379 R-XTR-204662 https://reactome.org/PathwayBrowser/#/R-XTR-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Xenopus tropicalis 15379 R-XTR-2066787 https://reactome.org/PathwayBrowser/#/R-XTR-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Xenopus tropicalis 15379 R-XTR-209823 https://reactome.org/PathwayBrowser/#/R-XTR-209823 Tyrosine is hydroxylated to dopa IEA Xenopus tropicalis 15379 R-XTR-209845 https://reactome.org/PathwayBrowser/#/R-XTR-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Xenopus tropicalis 15379 R-XTR-209891 https://reactome.org/PathwayBrowser/#/R-XTR-209891 Dopamine is oxidised to noradrenaline IEA Xenopus tropicalis 15379 R-XTR-211873 https://reactome.org/PathwayBrowser/#/R-XTR-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Xenopus tropicalis 15379 R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 15379 R-XTR-211881 https://reactome.org/PathwayBrowser/#/R-XTR-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Xenopus tropicalis 15379 R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 15379 R-XTR-211904 https://reactome.org/PathwayBrowser/#/R-XTR-211904 CYP4F12 18-hydroxylates ARA IEA Xenopus tropicalis 15379 R-XTR-211919 https://reactome.org/PathwayBrowser/#/R-XTR-211919 CYP4F8 19-hydroxylates PGH2 IEA Xenopus tropicalis 15379 R-XTR-211923 https://reactome.org/PathwayBrowser/#/R-XTR-211923 CYP26C1 4-hydroxylates 9cRA IEA Xenopus tropicalis 15379 R-XTR-211924 https://reactome.org/PathwayBrowser/#/R-XTR-211924 CYP4B1 12-hydroxylates ARA IEA Xenopus tropicalis 15379 R-XTR-211948 https://reactome.org/PathwayBrowser/#/R-XTR-211948 CYP3A4 can N-demethylate loperamide IEA Xenopus tropicalis 15379 R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 15379 R-XTR-211960 https://reactome.org/PathwayBrowser/#/R-XTR-211960 CYP2U1 19-hydroxylates ARA IEA Xenopus tropicalis 15379 R-XTR-211962 https://reactome.org/PathwayBrowser/#/R-XTR-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Xenopus tropicalis 15379 R-XTR-211966 https://reactome.org/PathwayBrowser/#/R-XTR-211966 CYP2D6 4-hydroxylates debrisoquine IEA Xenopus tropicalis 15379 R-XTR-211968 https://reactome.org/PathwayBrowser/#/R-XTR-211968 CYP2W1 oxidises INDOL IEA Xenopus tropicalis 15379 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 15379 R-XTR-211991 https://reactome.org/PathwayBrowser/#/R-XTR-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Xenopus tropicalis 15379 R-XTR-212005 https://reactome.org/PathwayBrowser/#/R-XTR-212005 CYP2F1 dehydrogenates 3-methylindole IEA Xenopus tropicalis 15379 R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 15379 R-XTR-213175 https://reactome.org/PathwayBrowser/#/R-XTR-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 15379 R-XTR-215526 https://reactome.org/PathwayBrowser/#/R-XTR-215526 CYP4F3 20-hydroxylates LTB4 IEA Xenopus tropicalis 15379 R-XTR-2160492 https://reactome.org/PathwayBrowser/#/R-XTR-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Xenopus tropicalis 15379 R-XTR-2161745 https://reactome.org/PathwayBrowser/#/R-XTR-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 15379 R-XTR-2161792 https://reactome.org/PathwayBrowser/#/R-XTR-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 15379 R-XTR-2161814 https://reactome.org/PathwayBrowser/#/R-XTR-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Xenopus tropicalis 15379 R-XTR-2161890 https://reactome.org/PathwayBrowser/#/R-XTR-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Xenopus tropicalis 15379 R-XTR-2161899 https://reactome.org/PathwayBrowser/#/R-XTR-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Xenopus tropicalis 15379 R-XTR-2161907 https://reactome.org/PathwayBrowser/#/R-XTR-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Xenopus tropicalis 15379 R-XTR-2161917 https://reactome.org/PathwayBrowser/#/R-XTR-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Xenopus tropicalis 15379 R-XTR-2161940 https://reactome.org/PathwayBrowser/#/R-XTR-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Xenopus tropicalis 15379 R-XTR-2161950 https://reactome.org/PathwayBrowser/#/R-XTR-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Xenopus tropicalis 15379 R-XTR-2161951 https://reactome.org/PathwayBrowser/#/R-XTR-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Xenopus tropicalis 15379 R-XTR-2162002 https://reactome.org/PathwayBrowser/#/R-XTR-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Xenopus tropicalis 15379 R-XTR-2162194 https://reactome.org/PathwayBrowser/#/R-XTR-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Xenopus tropicalis 15379 R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 15379 R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 15379 R-XTR-2172678 https://reactome.org/PathwayBrowser/#/R-XTR-2172678 PHF8 demethylates histone H4K20me1 IEA Xenopus tropicalis 15379 R-XTR-2309787 https://reactome.org/PathwayBrowser/#/R-XTR-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Xenopus tropicalis 15379 R-XTR-2395340 https://reactome.org/PathwayBrowser/#/R-XTR-2395340 Formation of hydroxyallysine by LOX IEA Xenopus tropicalis 15379 R-XTR-265296 https://reactome.org/PathwayBrowser/#/R-XTR-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Xenopus tropicalis 15379 R-XTR-3204311 https://reactome.org/PathwayBrowser/#/R-XTR-3204311 AOX1 oxidises PXL to PDXate IEA Xenopus tropicalis 15379 R-XTR-3299680 https://reactome.org/PathwayBrowser/#/R-XTR-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Xenopus tropicalis 15379 R-XTR-3299682 https://reactome.org/PathwayBrowser/#/R-XTR-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Xenopus tropicalis 15379 R-XTR-3299691 https://reactome.org/PathwayBrowser/#/R-XTR-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Xenopus tropicalis 15379 R-XTR-3341294 https://reactome.org/PathwayBrowser/#/R-XTR-3341294 Superoxide reduces cytochrome c IEA Xenopus tropicalis 15379 R-XTR-3777112 https://reactome.org/PathwayBrowser/#/R-XTR-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Xenopus tropicalis 15379 R-XTR-389639 https://reactome.org/PathwayBrowser/#/R-XTR-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Xenopus tropicalis 15379 R-XTR-389821 https://reactome.org/PathwayBrowser/#/R-XTR-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Xenopus tropicalis 15379 R-XTR-389842 https://reactome.org/PathwayBrowser/#/R-XTR-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Xenopus tropicalis 15379 R-XTR-389862 https://reactome.org/PathwayBrowser/#/R-XTR-389862 Conversion of glyoxylate to oxalate IEA Xenopus tropicalis 15379 R-XTR-389889 https://reactome.org/PathwayBrowser/#/R-XTR-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Xenopus tropicalis 15379 R-XTR-389891 https://reactome.org/PathwayBrowser/#/R-XTR-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Xenopus tropicalis 15379 R-XTR-390256 https://reactome.org/PathwayBrowser/#/R-XTR-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Xenopus tropicalis 15379 R-XTR-428259 https://reactome.org/PathwayBrowser/#/R-XTR-428259 DEGS1 dehydrogenates dihydroceramide IEA Xenopus tropicalis 15379 R-XTR-428260 https://reactome.org/PathwayBrowser/#/R-XTR-428260 DEGS2 oxygenates dihydroceramide IEA Xenopus tropicalis 15379 R-XTR-5164399 https://reactome.org/PathwayBrowser/#/R-XTR-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Xenopus tropicalis 15379 R-XTR-5218841 https://reactome.org/PathwayBrowser/#/R-XTR-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Xenopus tropicalis 15379 R-XTR-5340214 https://reactome.org/PathwayBrowser/#/R-XTR-5340214 CYGB binds O2 IEA Xenopus tropicalis 15379 R-XTR-5340226 https://reactome.org/PathwayBrowser/#/R-XTR-5340226 CYGB dioxygenates NO IEA Xenopus tropicalis 15379 R-XTR-5362525 https://reactome.org/PathwayBrowser/#/R-XTR-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Xenopus tropicalis 15379 R-XTR-5423647 https://reactome.org/PathwayBrowser/#/R-XTR-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Xenopus tropicalis 15379 R-XTR-5423664 https://reactome.org/PathwayBrowser/#/R-XTR-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Xenopus tropicalis 15379 R-XTR-5423672 https://reactome.org/PathwayBrowser/#/R-XTR-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Xenopus tropicalis 15379 R-XTR-5602295 https://reactome.org/PathwayBrowser/#/R-XTR-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Xenopus tropicalis 15379 R-XTR-5662692 https://reactome.org/PathwayBrowser/#/R-XTR-5662692 Dopa is oxidized to dopaquinone by TYR IEA Xenopus tropicalis 15379 R-XTR-5668629 https://reactome.org/PathwayBrowser/#/R-XTR-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Xenopus tropicalis 15379 R-XTR-5668718 https://reactome.org/PathwayBrowser/#/R-XTR-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 15379 R-XTR-5668731 https://reactome.org/PathwayBrowser/#/R-XTR-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 15379 R-XTR-5690565 https://reactome.org/PathwayBrowser/#/R-XTR-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Xenopus tropicalis 15379 R-XTR-5691107 https://reactome.org/PathwayBrowser/#/R-XTR-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Xenopus tropicalis 15379 R-XTR-5693681 https://reactome.org/PathwayBrowser/#/R-XTR-5693681 DUOX1,2 reduce O2 to H2O2 IEA Xenopus tropicalis 15379 R-XTR-5693761 https://reactome.org/PathwayBrowser/#/R-XTR-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Xenopus tropicalis 15379 R-XTR-5696119 https://reactome.org/PathwayBrowser/#/R-XTR-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Xenopus tropicalis 15379 R-XTR-5696131 https://reactome.org/PathwayBrowser/#/R-XTR-5696131 AOC1 deaminates Hist IEA Xenopus tropicalis 15379 R-XTR-5696183 https://reactome.org/PathwayBrowser/#/R-XTR-5696183 AOC3 deaminates BZAM IEA Xenopus tropicalis 15379 R-XTR-6783880 https://reactome.org/PathwayBrowser/#/R-XTR-6783880 PIPOX oxidises PPCA to P6C IEA Xenopus tropicalis 15379 R-XTR-6786239 https://reactome.org/PathwayBrowser/#/R-XTR-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Xenopus tropicalis 15379 R-XTR-6787811 https://reactome.org/PathwayBrowser/#/R-XTR-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Xenopus tropicalis 15379 R-XTR-6789092 https://reactome.org/PathwayBrowser/#/R-XTR-6789092 NOX2 generates superoxide anion from oxygen IEA Xenopus tropicalis 15379 R-XTR-6807053 https://reactome.org/PathwayBrowser/#/R-XTR-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Xenopus tropicalis 15379 R-XTR-6807214 https://reactome.org/PathwayBrowser/#/R-XTR-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Xenopus tropicalis 15379 R-XTR-6814153 https://reactome.org/PathwayBrowser/#/R-XTR-6814153 ADO oxidises 2AET to HTAU IEA Xenopus tropicalis 15379 R-XTR-71118 https://reactome.org/PathwayBrowser/#/R-XTR-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Xenopus tropicalis 15379 R-XTR-71163 https://reactome.org/PathwayBrowser/#/R-XTR-71163 HPD dioxygenates HPP IEA Xenopus tropicalis 15379 R-XTR-71188 https://reactome.org/PathwayBrowser/#/R-XTR-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Xenopus tropicalis 15379 R-XTR-71200 https://reactome.org/PathwayBrowser/#/R-XTR-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Xenopus tropicalis 15379 R-XTR-71218 https://reactome.org/PathwayBrowser/#/R-XTR-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Xenopus tropicalis 15379 R-XTR-71241 https://reactome.org/PathwayBrowser/#/R-XTR-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Xenopus tropicalis 15379 R-XTR-71261 https://reactome.org/PathwayBrowser/#/R-XTR-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Xenopus tropicalis 15379 R-XTR-74247 https://reactome.org/PathwayBrowser/#/R-XTR-74247 XDH oxidizes hypoxanthine to form xanthine IEA Xenopus tropicalis 15379 R-XTR-74258 https://reactome.org/PathwayBrowser/#/R-XTR-74258 XDH oxidizes xanthine to form urate IEA Xenopus tropicalis 15379 R-XTR-76031 https://reactome.org/PathwayBrowser/#/R-XTR-76031 2 H2O2 => O2 + 2 H2O IEA Xenopus tropicalis 15379 R-XTR-76354 https://reactome.org/PathwayBrowser/#/R-XTR-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Xenopus tropicalis 15379 R-XTR-76397 https://reactome.org/PathwayBrowser/#/R-XTR-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Xenopus tropicalis 15379 R-XTR-76416 https://reactome.org/PathwayBrowser/#/R-XTR-76416 Benzene is hydroxylated to phenol IEA Xenopus tropicalis 15379 R-XTR-76453 https://reactome.org/PathwayBrowser/#/R-XTR-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Xenopus tropicalis 15379 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 15379 R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 15379 R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 15379 R-XTR-8865107 https://reactome.org/PathwayBrowser/#/R-XTR-8865107 MICAL1 produces NADP+, H2O2 IEA Xenopus tropicalis 15379 R-XTR-8878581 https://reactome.org/PathwayBrowser/#/R-XTR-8878581 TYRP1 oxidises DHICA to IQCA IEA Xenopus tropicalis 15379 R-XTR-888614 https://reactome.org/PathwayBrowser/#/R-XTR-888614 IDO2 dioxygenates L-Trp to NFK IEA Xenopus tropicalis 15379 R-XTR-8953398 https://reactome.org/PathwayBrowser/#/R-XTR-8953398 PIR oxygenates quercetin IEA Xenopus tropicalis 15379 R-XTR-8956458 https://reactome.org/PathwayBrowser/#/R-XTR-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Xenopus tropicalis 15379 R-XTR-8981610 https://reactome.org/PathwayBrowser/#/R-XTR-8981610 Neuroglobin binds oxygen IEA Xenopus tropicalis 15379 R-XTR-8981621 https://reactome.org/PathwayBrowser/#/R-XTR-8981621 Neuroglobin:oxygen dissociates IEA Xenopus tropicalis 15379 R-XTR-8982617 https://reactome.org/PathwayBrowser/#/R-XTR-8982617 CYGB:O2 dissociates IEA Xenopus tropicalis 15379 R-XTR-9018858 https://reactome.org/PathwayBrowser/#/R-XTR-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Xenopus tropicalis 15379 R-XTR-9018859 https://reactome.org/PathwayBrowser/#/R-XTR-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Xenopus tropicalis 15379 R-XTR-9018863 https://reactome.org/PathwayBrowser/#/R-XTR-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Xenopus tropicalis 15379 R-XTR-9018880 https://reactome.org/PathwayBrowser/#/R-XTR-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Xenopus tropicalis 15379 R-XTR-9018894 https://reactome.org/PathwayBrowser/#/R-XTR-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Xenopus tropicalis 15379 R-XTR-9020251 https://reactome.org/PathwayBrowser/#/R-XTR-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Xenopus tropicalis 15379 R-XTR-9020259 https://reactome.org/PathwayBrowser/#/R-XTR-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Xenopus tropicalis 15379 R-XTR-9020261 https://reactome.org/PathwayBrowser/#/R-XTR-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Xenopus tropicalis 15379 R-XTR-9020264 https://reactome.org/PathwayBrowser/#/R-XTR-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Xenopus tropicalis 15379 R-XTR-9020282 https://reactome.org/PathwayBrowser/#/R-XTR-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Xenopus tropicalis 15379 R-XTR-9024997 https://reactome.org/PathwayBrowser/#/R-XTR-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Xenopus tropicalis 15379 R-XTR-9025996 https://reactome.org/PathwayBrowser/#/R-XTR-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Xenopus tropicalis 15379 R-XTR-9026005 https://reactome.org/PathwayBrowser/#/R-XTR-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Xenopus tropicalis 15379 R-XTR-9026405 https://reactome.org/PathwayBrowser/#/R-XTR-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Xenopus tropicalis 15379 R-XTR-9026408 https://reactome.org/PathwayBrowser/#/R-XTR-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Xenopus tropicalis 15379 R-XTR-9027043 https://reactome.org/PathwayBrowser/#/R-XTR-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Xenopus tropicalis 15379 R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 15379 R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 15379 R-XTR-9027532 https://reactome.org/PathwayBrowser/#/R-XTR-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Xenopus tropicalis 15379 R-XTR-9027607 https://reactome.org/PathwayBrowser/#/R-XTR-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Xenopus tropicalis 15379 R-XTR-9027624 https://reactome.org/PathwayBrowser/#/R-XTR-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Xenopus tropicalis 15379 R-XTR-9027627 https://reactome.org/PathwayBrowser/#/R-XTR-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Xenopus tropicalis 15379 R-XTR-9027628 https://reactome.org/PathwayBrowser/#/R-XTR-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Xenopus tropicalis 15379 R-XTR-9027633 https://reactome.org/PathwayBrowser/#/R-XTR-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Xenopus tropicalis 15379 R-XTR-9028255 https://reactome.org/PathwayBrowser/#/R-XTR-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Xenopus tropicalis 15379 R-XTR-917891 https://reactome.org/PathwayBrowser/#/R-XTR-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Xenopus tropicalis 15379 R-XTR-917933 https://reactome.org/PathwayBrowser/#/R-XTR-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Xenopus tropicalis 15379 R-XTR-9629578 https://reactome.org/PathwayBrowser/#/R-XTR-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Xenopus tropicalis 15379 R-XTR-9629591 https://reactome.org/PathwayBrowser/#/R-XTR-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Xenopus tropicalis 15379 R-XTR-9629869 https://reactome.org/PathwayBrowser/#/R-XTR-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Xenopus tropicalis 15379 R-XTR-9629888 https://reactome.org/PathwayBrowser/#/R-XTR-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Xenopus tropicalis 15379 R-XTR-9630022 https://reactome.org/PathwayBrowser/#/R-XTR-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Xenopus tropicalis 15379 R-XTR-9630769 https://reactome.org/PathwayBrowser/#/R-XTR-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Xenopus tropicalis 15379 R-XTR-9630993 https://reactome.org/PathwayBrowser/#/R-XTR-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Xenopus tropicalis 15379 R-XTR-965019 https://reactome.org/PathwayBrowser/#/R-XTR-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Xenopus tropicalis 15379 R-XTR-965079 https://reactome.org/PathwayBrowser/#/R-XTR-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Xenopus tropicalis 15379 R-XTR-9709360 https://reactome.org/PathwayBrowser/#/R-XTR-9709360 H2O2 reduces MetHb IEA Xenopus tropicalis 15379 R-XTR-9749986 https://reactome.org/PathwayBrowser/#/R-XTR-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Xenopus tropicalis 15379 R-XTR-9750016 https://reactome.org/PathwayBrowser/#/R-XTR-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Xenopus tropicalis 15379 R-XTR-9753285 https://reactome.org/PathwayBrowser/#/R-XTR-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Xenopus tropicalis 15379 R-XTR-9756138 https://reactome.org/PathwayBrowser/#/R-XTR-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Xenopus tropicalis 15379 R-XTR-9756162 https://reactome.org/PathwayBrowser/#/R-XTR-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Xenopus tropicalis 15379 R-XTR-9756169 https://reactome.org/PathwayBrowser/#/R-XTR-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Xenopus tropicalis 15379 R-XTR-9756180 https://reactome.org/PathwayBrowser/#/R-XTR-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Xenopus tropicalis 15379 R-XTR-975635 https://reactome.org/PathwayBrowser/#/R-XTR-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Xenopus tropicalis 15379 R-XTR-9758674 https://reactome.org/PathwayBrowser/#/R-XTR-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Xenopus tropicalis 15379 R-XTR-9817575 https://reactome.org/PathwayBrowser/#/R-XTR-9817575 ERO1B oxidizes P4HB IEA Xenopus tropicalis 15399 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 15399 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 15399 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 15399 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 15399 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 15399 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 15399 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 15399 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 15399 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 15400 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 15400 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 15400 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 15400 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 15400 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 15400 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 15400 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 15400 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 15400 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 15409 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 15409 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 15409 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 15409 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 15409 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 15409 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 15409 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 15409 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 15409 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 15440 R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 15440 R-BTA-191402 https://reactome.org/PathwayBrowser/#/R-BTA-191402 Reduction of presqualene diphosphate to form squalene IEA Bos taurus 15440 R-BTA-8850326 https://reactome.org/PathwayBrowser/#/R-BTA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Bos taurus 15440 R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 15440 R-CFA-191402 https://reactome.org/PathwayBrowser/#/R-CFA-191402 Reduction of presqualene diphosphate to form squalene IEA Canis familiaris 15440 R-CFA-8850326 https://reactome.org/PathwayBrowser/#/R-CFA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Canis familiaris 15440 R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 15440 R-DDI-191402 https://reactome.org/PathwayBrowser/#/R-DDI-191402 Reduction of presqualene diphosphate to form squalene IEA Dictyostelium discoideum 15440 R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 15440 R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 15440 R-GGA-191402 https://reactome.org/PathwayBrowser/#/R-GGA-191402 Reduction of presqualene diphosphate to form squalene IEA Gallus gallus 15440 R-GGA-8850326 https://reactome.org/PathwayBrowser/#/R-GGA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Gallus gallus 15440 R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 15440 R-HSA-191402 https://reactome.org/PathwayBrowser/#/R-HSA-191402 Reduction of presqualene diphosphate to form squalene TAS Homo sapiens 15440 R-HSA-8850326 https://reactome.org/PathwayBrowser/#/R-HSA-8850326 TCR binds self-lipid-based antigen via CD1 TAS Homo sapiens 15440 R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 15440 R-MMU-191402 https://reactome.org/PathwayBrowser/#/R-MMU-191402 Reduction of presqualene diphosphate to form squalene IEA Mus musculus 15440 R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 15440 R-RNO-191402 https://reactome.org/PathwayBrowser/#/R-RNO-191402 Reduction of presqualene diphosphate to form squalene IEA Rattus norvegicus 15440 R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 15440 R-SCE-191402 https://reactome.org/PathwayBrowser/#/R-SCE-191402 Reduction of presqualene diphosphate to form squalene IEA Saccharomyces cerevisiae 15440 R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 15440 R-SPO-191402 https://reactome.org/PathwayBrowser/#/R-SPO-191402 Reduction of presqualene diphosphate to form squalene IEA Schizosaccharomyces pombe 15440 R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 15440 R-SSC-191402 https://reactome.org/PathwayBrowser/#/R-SSC-191402 Reduction of presqualene diphosphate to form squalene IEA Sus scrofa 15440 R-SSC-8850326 https://reactome.org/PathwayBrowser/#/R-SSC-8850326 TCR binds self-lipid-based antigen via CD1 IEA Sus scrofa 15440 R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 15440 R-XTR-191402 https://reactome.org/PathwayBrowser/#/R-XTR-191402 Reduction of presqualene diphosphate to form squalene IEA Xenopus tropicalis 15441 R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 15441 R-BTA-191366 https://reactome.org/PathwayBrowser/#/R-BTA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Bos taurus 15441 R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 15441 R-CFA-191366 https://reactome.org/PathwayBrowser/#/R-CFA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Canis familiaris 15441 R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 15441 R-DDI-191366 https://reactome.org/PathwayBrowser/#/R-DDI-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Dictyostelium discoideum 15441 R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 15441 R-DRE-191366 https://reactome.org/PathwayBrowser/#/R-DRE-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Danio rerio 15441 R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 15441 R-GGA-191366 https://reactome.org/PathwayBrowser/#/R-GGA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Gallus gallus 15441 R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 15441 R-HSA-191366 https://reactome.org/PathwayBrowser/#/R-HSA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol TAS Homo sapiens 15441 R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 15441 R-MMU-191366 https://reactome.org/PathwayBrowser/#/R-MMU-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Mus musculus 15441 R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 15441 R-RNO-191366 https://reactome.org/PathwayBrowser/#/R-RNO-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Rattus norvegicus 15441 R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 15441 R-SCE-191366 https://reactome.org/PathwayBrowser/#/R-SCE-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Saccharomyces cerevisiae 15441 R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 15441 R-SPO-191366 https://reactome.org/PathwayBrowser/#/R-SPO-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Schizosaccharomyces pombe 15441 R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 15441 R-SSC-191366 https://reactome.org/PathwayBrowser/#/R-SSC-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Sus scrofa 15441 R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 15441 R-XTR-191366 https://reactome.org/PathwayBrowser/#/R-XTR-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Xenopus tropicalis 15442 R-BTA-191402 https://reactome.org/PathwayBrowser/#/R-BTA-191402 Reduction of presqualene diphosphate to form squalene IEA Bos taurus 15442 R-BTA-191405 https://reactome.org/PathwayBrowser/#/R-BTA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Bos taurus 15442 R-BTA-8952137 https://reactome.org/PathwayBrowser/#/R-BTA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Bos taurus 15442 R-CEL-8952137 https://reactome.org/PathwayBrowser/#/R-CEL-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Caenorhabditis elegans 15442 R-CFA-191402 https://reactome.org/PathwayBrowser/#/R-CFA-191402 Reduction of presqualene diphosphate to form squalene IEA Canis familiaris 15442 R-CFA-191405 https://reactome.org/PathwayBrowser/#/R-CFA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Canis familiaris 15442 R-CFA-8952137 https://reactome.org/PathwayBrowser/#/R-CFA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Canis familiaris 15442 R-DDI-191402 https://reactome.org/PathwayBrowser/#/R-DDI-191402 Reduction of presqualene diphosphate to form squalene IEA Dictyostelium discoideum 15442 R-DDI-191405 https://reactome.org/PathwayBrowser/#/R-DDI-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Dictyostelium discoideum 15442 R-DDI-8952137 https://reactome.org/PathwayBrowser/#/R-DDI-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Dictyostelium discoideum 15442 R-DME-8952137 https://reactome.org/PathwayBrowser/#/R-DME-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Drosophila melanogaster 15442 R-DRE-8952137 https://reactome.org/PathwayBrowser/#/R-DRE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Danio rerio 15442 R-GGA-191402 https://reactome.org/PathwayBrowser/#/R-GGA-191402 Reduction of presqualene diphosphate to form squalene IEA Gallus gallus 15442 R-GGA-191405 https://reactome.org/PathwayBrowser/#/R-GGA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Gallus gallus 15442 R-GGA-8952137 https://reactome.org/PathwayBrowser/#/R-GGA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Gallus gallus 15442 R-HSA-191402 https://reactome.org/PathwayBrowser/#/R-HSA-191402 Reduction of presqualene diphosphate to form squalene TAS Homo sapiens 15442 R-HSA-191405 https://reactome.org/PathwayBrowser/#/R-HSA-191405 Two FPP molecules dimerize to form presqualene diphosphate TAS Homo sapiens 15442 R-HSA-8952137 https://reactome.org/PathwayBrowser/#/R-HSA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate TAS Homo sapiens 15442 R-MMU-191402 https://reactome.org/PathwayBrowser/#/R-MMU-191402 Reduction of presqualene diphosphate to form squalene IEA Mus musculus 15442 R-MMU-191405 https://reactome.org/PathwayBrowser/#/R-MMU-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Mus musculus 15442 R-MMU-8952137 https://reactome.org/PathwayBrowser/#/R-MMU-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Mus musculus 15442 R-RNO-191402 https://reactome.org/PathwayBrowser/#/R-RNO-191402 Reduction of presqualene diphosphate to form squalene IEA Rattus norvegicus 15442 R-RNO-191405 https://reactome.org/PathwayBrowser/#/R-RNO-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Rattus norvegicus 15442 R-RNO-8952137 https://reactome.org/PathwayBrowser/#/R-RNO-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Rattus norvegicus 15442 R-SCE-191402 https://reactome.org/PathwayBrowser/#/R-SCE-191402 Reduction of presqualene diphosphate to form squalene IEA Saccharomyces cerevisiae 15442 R-SCE-191405 https://reactome.org/PathwayBrowser/#/R-SCE-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Saccharomyces cerevisiae 15442 R-SCE-8952137 https://reactome.org/PathwayBrowser/#/R-SCE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Saccharomyces cerevisiae 15442 R-SPO-191402 https://reactome.org/PathwayBrowser/#/R-SPO-191402 Reduction of presqualene diphosphate to form squalene IEA Schizosaccharomyces pombe 15442 R-SPO-191405 https://reactome.org/PathwayBrowser/#/R-SPO-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Schizosaccharomyces pombe 15442 R-SSC-191402 https://reactome.org/PathwayBrowser/#/R-SSC-191402 Reduction of presqualene diphosphate to form squalene IEA Sus scrofa 15442 R-SSC-191405 https://reactome.org/PathwayBrowser/#/R-SSC-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Sus scrofa 15442 R-SSC-8952137 https://reactome.org/PathwayBrowser/#/R-SSC-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Sus scrofa 15442 R-XTR-191402 https://reactome.org/PathwayBrowser/#/R-XTR-191402 Reduction of presqualene diphosphate to form squalene IEA Xenopus tropicalis 15442 R-XTR-191405 https://reactome.org/PathwayBrowser/#/R-XTR-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Xenopus tropicalis 15442 R-XTR-8952137 https://reactome.org/PathwayBrowser/#/R-XTR-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Xenopus tropicalis 15444 R-MTU-868657 https://reactome.org/PathwayBrowser/#/R-MTU-868657 Glucanotrehalose is hydrolyzed to 1,4-alpha-glucan and trehalose TAS Mycobacterium tuberculosis 15444 R-MTU-868658 https://reactome.org/PathwayBrowser/#/R-MTU-868658 1,4-alpha-glucan is converted to glucanotrehalose TAS Mycobacterium tuberculosis 15449 R-BTA-508369 https://reactome.org/PathwayBrowser/#/R-BTA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Bos taurus 15449 R-BTA-70837 https://reactome.org/PathwayBrowser/#/R-BTA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Bos taurus 15449 R-CEL-508369 https://reactome.org/PathwayBrowser/#/R-CEL-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Caenorhabditis elegans 15449 R-CEL-70837 https://reactome.org/PathwayBrowser/#/R-CEL-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Caenorhabditis elegans 15449 R-CFA-508369 https://reactome.org/PathwayBrowser/#/R-CFA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Canis familiaris 15449 R-CFA-70837 https://reactome.org/PathwayBrowser/#/R-CFA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Canis familiaris 15449 R-DDI-508369 https://reactome.org/PathwayBrowser/#/R-DDI-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Dictyostelium discoideum 15449 R-DDI-70837 https://reactome.org/PathwayBrowser/#/R-DDI-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Dictyostelium discoideum 15449 R-DME-508369 https://reactome.org/PathwayBrowser/#/R-DME-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Drosophila melanogaster 15449 R-DME-70837 https://reactome.org/PathwayBrowser/#/R-DME-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Drosophila melanogaster 15449 R-DRE-508369 https://reactome.org/PathwayBrowser/#/R-DRE-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Danio rerio 15449 R-DRE-70837 https://reactome.org/PathwayBrowser/#/R-DRE-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Danio rerio 15449 R-GGA-508369 https://reactome.org/PathwayBrowser/#/R-GGA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Gallus gallus 15449 R-GGA-70837 https://reactome.org/PathwayBrowser/#/R-GGA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Gallus gallus 15449 R-HSA-508369 https://reactome.org/PathwayBrowser/#/R-HSA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ TAS Homo sapiens 15449 R-HSA-70830 https://reactome.org/PathwayBrowser/#/R-HSA-70830 tiglyl-CoA + H2O <=> alpha-methyl-beta-hydroxybutyryl-CoA TAS Homo sapiens 15449 R-HSA-70837 https://reactome.org/PathwayBrowser/#/R-HSA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ TAS Homo sapiens 15449 R-MMU-508369 https://reactome.org/PathwayBrowser/#/R-MMU-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Mus musculus 15449 R-MMU-70837 https://reactome.org/PathwayBrowser/#/R-MMU-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Mus musculus 15449 R-RNO-508369 https://reactome.org/PathwayBrowser/#/R-RNO-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Rattus norvegicus 15449 R-RNO-70837 https://reactome.org/PathwayBrowser/#/R-RNO-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Rattus norvegicus 15449 R-SSC-508369 https://reactome.org/PathwayBrowser/#/R-SSC-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Sus scrofa 15449 R-SSC-70837 https://reactome.org/PathwayBrowser/#/R-SSC-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Sus scrofa 15449 R-XTR-508369 https://reactome.org/PathwayBrowser/#/R-XTR-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Xenopus tropicalis 15449 R-XTR-70837 https://reactome.org/PathwayBrowser/#/R-XTR-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Xenopus tropicalis 15453 R-BTA-77312 https://reactome.org/PathwayBrowser/#/R-BTA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Bos taurus 15453 R-BTA-77314 https://reactome.org/PathwayBrowser/#/R-BTA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Bos taurus 15453 R-CEL-77312 https://reactome.org/PathwayBrowser/#/R-CEL-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Caenorhabditis elegans 15453 R-CEL-77314 https://reactome.org/PathwayBrowser/#/R-CEL-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Caenorhabditis elegans 15453 R-CFA-77312 https://reactome.org/PathwayBrowser/#/R-CFA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Canis familiaris 15453 R-CFA-77314 https://reactome.org/PathwayBrowser/#/R-CFA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Canis familiaris 15453 R-DDI-77314 https://reactome.org/PathwayBrowser/#/R-DDI-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Dictyostelium discoideum 15453 R-DME-77314 https://reactome.org/PathwayBrowser/#/R-DME-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Drosophila melanogaster 15453 R-DRE-77312 https://reactome.org/PathwayBrowser/#/R-DRE-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Danio rerio 15453 R-GGA-77312 https://reactome.org/PathwayBrowser/#/R-GGA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Gallus gallus 15453 R-HSA-77312 https://reactome.org/PathwayBrowser/#/R-HSA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H TAS Homo sapiens 15453 R-HSA-77314 https://reactome.org/PathwayBrowser/#/R-HSA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA TAS Homo sapiens 15453 R-MMU-77312 https://reactome.org/PathwayBrowser/#/R-MMU-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Mus musculus 15453 R-MMU-77314 https://reactome.org/PathwayBrowser/#/R-MMU-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Mus musculus 15453 R-RNO-77312 https://reactome.org/PathwayBrowser/#/R-RNO-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Rattus norvegicus 15453 R-RNO-77314 https://reactome.org/PathwayBrowser/#/R-RNO-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Rattus norvegicus 15453 R-SSC-77312 https://reactome.org/PathwayBrowser/#/R-SSC-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Sus scrofa 15453 R-SSC-77314 https://reactome.org/PathwayBrowser/#/R-SSC-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Sus scrofa 15453 R-XTR-77312 https://reactome.org/PathwayBrowser/#/R-XTR-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Xenopus tropicalis 15453 R-XTR-77314 https://reactome.org/PathwayBrowser/#/R-XTR-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Xenopus tropicalis 15456 R-BTA-5676637 https://reactome.org/PathwayBrowser/#/R-BTA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Bos taurus 15456 R-CEL-5676637 https://reactome.org/PathwayBrowser/#/R-CEL-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Caenorhabditis elegans 15456 R-CFA-5676637 https://reactome.org/PathwayBrowser/#/R-CFA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Canis familiaris 15456 R-CFA-8957389 https://reactome.org/PathwayBrowser/#/R-CFA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Canis familiaris 15456 R-DDI-5676637 https://reactome.org/PathwayBrowser/#/R-DDI-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Dictyostelium discoideum 15456 R-DDI-8957389 https://reactome.org/PathwayBrowser/#/R-DDI-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Dictyostelium discoideum 15456 R-DME-5676637 https://reactome.org/PathwayBrowser/#/R-DME-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Drosophila melanogaster 15456 R-DME-8957389 https://reactome.org/PathwayBrowser/#/R-DME-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Drosophila melanogaster 15456 R-DRE-5676637 https://reactome.org/PathwayBrowser/#/R-DRE-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Danio rerio 15456 R-GGA-5676637 https://reactome.org/PathwayBrowser/#/R-GGA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Gallus gallus 15456 R-GGA-8957389 https://reactome.org/PathwayBrowser/#/R-GGA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Gallus gallus 15456 R-HSA-5676637 https://reactome.org/PathwayBrowser/#/R-HSA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA TAS Homo sapiens 15456 R-HSA-8957389 https://reactome.org/PathwayBrowser/#/R-HSA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA TAS Homo sapiens 15456 R-MMU-5676637 https://reactome.org/PathwayBrowser/#/R-MMU-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Mus musculus 15456 R-PFA-5676637 https://reactome.org/PathwayBrowser/#/R-PFA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Plasmodium falciparum 15456 R-RNO-5676637 https://reactome.org/PathwayBrowser/#/R-RNO-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Rattus norvegicus 15456 R-RNO-8957389 https://reactome.org/PathwayBrowser/#/R-RNO-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Rattus norvegicus 15456 R-SCE-5676637 https://reactome.org/PathwayBrowser/#/R-SCE-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Saccharomyces cerevisiae 15456 R-SPO-5676637 https://reactome.org/PathwayBrowser/#/R-SPO-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Schizosaccharomyces pombe 15456 R-SSC-5676637 https://reactome.org/PathwayBrowser/#/R-SSC-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Sus scrofa 15456 R-SSC-8957389 https://reactome.org/PathwayBrowser/#/R-SSC-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Sus scrofa 15456 R-XTR-5676637 https://reactome.org/PathwayBrowser/#/R-XTR-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Xenopus tropicalis 15465 R-BTA-71010 https://reactome.org/PathwayBrowser/#/R-BTA-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Bos taurus 15465 R-BTA-71020 https://reactome.org/PathwayBrowser/#/R-BTA-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Bos taurus 15465 R-CEL-71010 https://reactome.org/PathwayBrowser/#/R-CEL-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Caenorhabditis elegans 15465 R-CEL-71020 https://reactome.org/PathwayBrowser/#/R-CEL-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Caenorhabditis elegans 15465 R-CFA-71010 https://reactome.org/PathwayBrowser/#/R-CFA-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Canis familiaris 15465 R-CFA-71020 https://reactome.org/PathwayBrowser/#/R-CFA-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Canis familiaris 15465 R-DDI-71020 https://reactome.org/PathwayBrowser/#/R-DDI-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Dictyostelium discoideum 15465 R-DRE-71010 https://reactome.org/PathwayBrowser/#/R-DRE-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Danio rerio 15465 R-DRE-71020 https://reactome.org/PathwayBrowser/#/R-DRE-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Danio rerio 15465 R-GGA-71010 https://reactome.org/PathwayBrowser/#/R-GGA-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Gallus gallus 15465 R-GGA-71020 https://reactome.org/PathwayBrowser/#/R-GGA-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Gallus gallus 15465 R-HSA-3322971 https://reactome.org/PathwayBrowser/#/R-HSA-3322971 Defective MUT does not isomerise L-MM-CoA to SUCC-CoA TAS Homo sapiens 15465 R-HSA-71010 https://reactome.org/PathwayBrowser/#/R-HSA-71010 MUT isomerises L-MM-CoA to SUCC-CoA TAS Homo sapiens 15465 R-HSA-71020 https://reactome.org/PathwayBrowser/#/R-HSA-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA TAS Homo sapiens 15465 R-MMU-71010 https://reactome.org/PathwayBrowser/#/R-MMU-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Mus musculus 15465 R-MMU-71020 https://reactome.org/PathwayBrowser/#/R-MMU-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Mus musculus 15465 R-RNO-71010 https://reactome.org/PathwayBrowser/#/R-RNO-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Rattus norvegicus 15465 R-RNO-71020 https://reactome.org/PathwayBrowser/#/R-RNO-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Rattus norvegicus 15465 R-SSC-71010 https://reactome.org/PathwayBrowser/#/R-SSC-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Sus scrofa 15465 R-SSC-71020 https://reactome.org/PathwayBrowser/#/R-SSC-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Sus scrofa 15465 R-XTR-71020 https://reactome.org/PathwayBrowser/#/R-XTR-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Xenopus tropicalis 15466 R-BTA-71020 https://reactome.org/PathwayBrowser/#/R-BTA-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Bos taurus 15466 R-BTA-71031 https://reactome.org/PathwayBrowser/#/R-BTA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Bos taurus 15466 R-CEL-71020 https://reactome.org/PathwayBrowser/#/R-CEL-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Caenorhabditis elegans 15466 R-CEL-71031 https://reactome.org/PathwayBrowser/#/R-CEL-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Caenorhabditis elegans 15466 R-CFA-71020 https://reactome.org/PathwayBrowser/#/R-CFA-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Canis familiaris 15466 R-CFA-71031 https://reactome.org/PathwayBrowser/#/R-CFA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Canis familiaris 15466 R-DDI-71020 https://reactome.org/PathwayBrowser/#/R-DDI-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Dictyostelium discoideum 15466 R-DDI-71031 https://reactome.org/PathwayBrowser/#/R-DDI-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Dictyostelium discoideum 15466 R-DRE-71020 https://reactome.org/PathwayBrowser/#/R-DRE-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Danio rerio 15466 R-DRE-71031 https://reactome.org/PathwayBrowser/#/R-DRE-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Danio rerio 15466 R-GGA-71020 https://reactome.org/PathwayBrowser/#/R-GGA-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Gallus gallus 15466 R-GGA-71031 https://reactome.org/PathwayBrowser/#/R-GGA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Gallus gallus 15466 R-HSA-71020 https://reactome.org/PathwayBrowser/#/R-HSA-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA TAS Homo sapiens 15466 R-HSA-71031 https://reactome.org/PathwayBrowser/#/R-HSA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate TAS Homo sapiens 15466 R-MMU-71020 https://reactome.org/PathwayBrowser/#/R-MMU-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Mus musculus 15466 R-MMU-71031 https://reactome.org/PathwayBrowser/#/R-MMU-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Mus musculus 15466 R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 15466 R-RNO-71020 https://reactome.org/PathwayBrowser/#/R-RNO-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Rattus norvegicus 15466 R-RNO-71031 https://reactome.org/PathwayBrowser/#/R-RNO-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Rattus norvegicus 15466 R-SSC-71020 https://reactome.org/PathwayBrowser/#/R-SSC-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Sus scrofa 15466 R-SSC-71031 https://reactome.org/PathwayBrowser/#/R-SSC-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Sus scrofa 15466 R-XTR-71020 https://reactome.org/PathwayBrowser/#/R-XTR-71020 D-methylmalonyl-CoA <=> L-methylmalonyl-CoA IEA Xenopus tropicalis 15466 R-XTR-71031 https://reactome.org/PathwayBrowser/#/R-XTR-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Xenopus tropicalis 15467 R-BTA-73918 https://reactome.org/PathwayBrowser/#/R-BTA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Bos taurus 15467 R-BTA-74180 https://reactome.org/PathwayBrowser/#/R-BTA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Bos taurus 15467 R-CEL-73918 https://reactome.org/PathwayBrowser/#/R-CEL-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Caenorhabditis elegans 15467 R-CEL-74180 https://reactome.org/PathwayBrowser/#/R-CEL-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Caenorhabditis elegans 15467 R-CFA-73918 https://reactome.org/PathwayBrowser/#/R-CFA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Canis familiaris 15467 R-CFA-74180 https://reactome.org/PathwayBrowser/#/R-CFA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Canis familiaris 15467 R-DDI-73918 https://reactome.org/PathwayBrowser/#/R-DDI-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Dictyostelium discoideum 15467 R-DDI-74180 https://reactome.org/PathwayBrowser/#/R-DDI-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Dictyostelium discoideum 15467 R-DME-73918 https://reactome.org/PathwayBrowser/#/R-DME-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Drosophila melanogaster 15467 R-DME-74180 https://reactome.org/PathwayBrowser/#/R-DME-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Drosophila melanogaster 15467 R-DRE-74180 https://reactome.org/PathwayBrowser/#/R-DRE-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Danio rerio 15467 R-GGA-73918 https://reactome.org/PathwayBrowser/#/R-GGA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Gallus gallus 15467 R-GGA-74180 https://reactome.org/PathwayBrowser/#/R-GGA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Gallus gallus 15467 R-HSA-73918 https://reactome.org/PathwayBrowser/#/R-HSA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH TAS Homo sapiens 15467 R-HSA-74180 https://reactome.org/PathwayBrowser/#/R-HSA-74180 HMG CoA => acetoacetic acid + acetyl CoA TAS Homo sapiens 15467 R-MMU-73918 https://reactome.org/PathwayBrowser/#/R-MMU-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Mus musculus 15467 R-MMU-74180 https://reactome.org/PathwayBrowser/#/R-MMU-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Mus musculus 15467 R-RNO-73918 https://reactome.org/PathwayBrowser/#/R-RNO-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Rattus norvegicus 15467 R-RNO-74180 https://reactome.org/PathwayBrowser/#/R-RNO-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Rattus norvegicus 15467 R-SCE-73918 https://reactome.org/PathwayBrowser/#/R-SCE-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Saccharomyces cerevisiae 15467 R-SPO-73918 https://reactome.org/PathwayBrowser/#/R-SPO-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Schizosaccharomyces pombe 15467 R-SSC-73918 https://reactome.org/PathwayBrowser/#/R-SSC-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Sus scrofa 15467 R-SSC-74180 https://reactome.org/PathwayBrowser/#/R-SSC-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Sus scrofa 15467 R-XTR-74180 https://reactome.org/PathwayBrowser/#/R-XTR-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Xenopus tropicalis 15475 R-BTA-389611 https://reactome.org/PathwayBrowser/#/R-BTA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Bos taurus 15475 R-BTA-389639 https://reactome.org/PathwayBrowser/#/R-BTA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Bos taurus 15475 R-CEL-389611 https://reactome.org/PathwayBrowser/#/R-CEL-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Caenorhabditis elegans 15475 R-CEL-389639 https://reactome.org/PathwayBrowser/#/R-CEL-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Caenorhabditis elegans 15475 R-CFA-389611 https://reactome.org/PathwayBrowser/#/R-CFA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Canis familiaris 15475 R-CFA-389639 https://reactome.org/PathwayBrowser/#/R-CFA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Canis familiaris 15475 R-DDI-389611 https://reactome.org/PathwayBrowser/#/R-DDI-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Dictyostelium discoideum 15475 R-DDI-389639 https://reactome.org/PathwayBrowser/#/R-DDI-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Dictyostelium discoideum 15475 R-DME-389611 https://reactome.org/PathwayBrowser/#/R-DME-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Drosophila melanogaster 15475 R-DRE-389611 https://reactome.org/PathwayBrowser/#/R-DRE-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Danio rerio 15475 R-DRE-389639 https://reactome.org/PathwayBrowser/#/R-DRE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Danio rerio 15475 R-GGA-389611 https://reactome.org/PathwayBrowser/#/R-GGA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Gallus gallus 15475 R-GGA-389639 https://reactome.org/PathwayBrowser/#/R-GGA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Gallus gallus 15475 R-HSA-389611 https://reactome.org/PathwayBrowser/#/R-HSA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA TAS Homo sapiens 15475 R-HSA-389639 https://reactome.org/PathwayBrowser/#/R-HSA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 TAS Homo sapiens 15475 R-MMU-389611 https://reactome.org/PathwayBrowser/#/R-MMU-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Mus musculus 15475 R-MMU-389639 https://reactome.org/PathwayBrowser/#/R-MMU-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Mus musculus 15475 R-RNO-389611 https://reactome.org/PathwayBrowser/#/R-RNO-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Rattus norvegicus 15475 R-RNO-389639 https://reactome.org/PathwayBrowser/#/R-RNO-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Rattus norvegicus 15475 R-SCE-389611 https://reactome.org/PathwayBrowser/#/R-SCE-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Saccharomyces cerevisiae 15475 R-SCE-389639 https://reactome.org/PathwayBrowser/#/R-SCE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Saccharomyces cerevisiae 15475 R-SPO-389611 https://reactome.org/PathwayBrowser/#/R-SPO-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Schizosaccharomyces pombe 15475 R-SSC-389611 https://reactome.org/PathwayBrowser/#/R-SSC-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Sus scrofa 15475 R-SSC-389639 https://reactome.org/PathwayBrowser/#/R-SSC-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Sus scrofa 15475 R-XTR-389611 https://reactome.org/PathwayBrowser/#/R-XTR-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Xenopus tropicalis 15475 R-XTR-389639 https://reactome.org/PathwayBrowser/#/R-XTR-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Xenopus tropicalis 15476 R-BTA-508369 https://reactome.org/PathwayBrowser/#/R-BTA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Bos taurus 15476 R-BTA-70837 https://reactome.org/PathwayBrowser/#/R-BTA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Bos taurus 15476 R-BTA-70844 https://reactome.org/PathwayBrowser/#/R-BTA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Bos taurus 15476 R-CEL-508369 https://reactome.org/PathwayBrowser/#/R-CEL-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Caenorhabditis elegans 15476 R-CEL-70837 https://reactome.org/PathwayBrowser/#/R-CEL-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Caenorhabditis elegans 15476 R-CEL-70844 https://reactome.org/PathwayBrowser/#/R-CEL-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Caenorhabditis elegans 15476 R-CFA-508369 https://reactome.org/PathwayBrowser/#/R-CFA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Canis familiaris 15476 R-CFA-70837 https://reactome.org/PathwayBrowser/#/R-CFA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Canis familiaris 15476 R-CFA-70844 https://reactome.org/PathwayBrowser/#/R-CFA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Canis familiaris 15476 R-DDI-508369 https://reactome.org/PathwayBrowser/#/R-DDI-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Dictyostelium discoideum 15476 R-DDI-70837 https://reactome.org/PathwayBrowser/#/R-DDI-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Dictyostelium discoideum 15476 R-DDI-70844 https://reactome.org/PathwayBrowser/#/R-DDI-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Dictyostelium discoideum 15476 R-DME-508369 https://reactome.org/PathwayBrowser/#/R-DME-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Drosophila melanogaster 15476 R-DME-70837 https://reactome.org/PathwayBrowser/#/R-DME-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Drosophila melanogaster 15476 R-DME-70844 https://reactome.org/PathwayBrowser/#/R-DME-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Drosophila melanogaster 15476 R-DRE-508369 https://reactome.org/PathwayBrowser/#/R-DRE-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Danio rerio 15476 R-DRE-70837 https://reactome.org/PathwayBrowser/#/R-DRE-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Danio rerio 15476 R-DRE-70844 https://reactome.org/PathwayBrowser/#/R-DRE-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Danio rerio 15476 R-GGA-508369 https://reactome.org/PathwayBrowser/#/R-GGA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Gallus gallus 15476 R-GGA-70837 https://reactome.org/PathwayBrowser/#/R-GGA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Gallus gallus 15476 R-GGA-70844 https://reactome.org/PathwayBrowser/#/R-GGA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Gallus gallus 15476 R-HSA-508369 https://reactome.org/PathwayBrowser/#/R-HSA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ TAS Homo sapiens 15476 R-HSA-70837 https://reactome.org/PathwayBrowser/#/R-HSA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ TAS Homo sapiens 15476 R-HSA-70844 https://reactome.org/PathwayBrowser/#/R-HSA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA TAS Homo sapiens 15476 R-MMU-508369 https://reactome.org/PathwayBrowser/#/R-MMU-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Mus musculus 15476 R-MMU-70837 https://reactome.org/PathwayBrowser/#/R-MMU-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Mus musculus 15476 R-MMU-70844 https://reactome.org/PathwayBrowser/#/R-MMU-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Mus musculus 15476 R-PFA-70844 https://reactome.org/PathwayBrowser/#/R-PFA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Plasmodium falciparum 15476 R-RNO-508369 https://reactome.org/PathwayBrowser/#/R-RNO-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Rattus norvegicus 15476 R-RNO-70837 https://reactome.org/PathwayBrowser/#/R-RNO-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Rattus norvegicus 15476 R-RNO-70844 https://reactome.org/PathwayBrowser/#/R-RNO-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Rattus norvegicus 15476 R-SSC-508369 https://reactome.org/PathwayBrowser/#/R-SSC-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Sus scrofa 15476 R-SSC-70837 https://reactome.org/PathwayBrowser/#/R-SSC-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Sus scrofa 15476 R-SSC-70844 https://reactome.org/PathwayBrowser/#/R-SSC-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Sus scrofa 15476 R-XTR-508369 https://reactome.org/PathwayBrowser/#/R-XTR-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Xenopus tropicalis 15476 R-XTR-70837 https://reactome.org/PathwayBrowser/#/R-XTR-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Xenopus tropicalis 15476 R-XTR-70844 https://reactome.org/PathwayBrowser/#/R-XTR-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Xenopus tropicalis 15478 R-BTA-70800 https://reactome.org/PathwayBrowser/#/R-BTA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Bos taurus 15478 R-CEL-70800 https://reactome.org/PathwayBrowser/#/R-CEL-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Caenorhabditis elegans 15478 R-CFA-70800 https://reactome.org/PathwayBrowser/#/R-CFA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Canis familiaris 15478 R-DDI-70800 https://reactome.org/PathwayBrowser/#/R-DDI-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Dictyostelium discoideum 15478 R-DME-70800 https://reactome.org/PathwayBrowser/#/R-DME-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Drosophila melanogaster 15478 R-GGA-70800 https://reactome.org/PathwayBrowser/#/R-GGA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Gallus gallus 15478 R-HSA-70800 https://reactome.org/PathwayBrowser/#/R-HSA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 TAS Homo sapiens 15478 R-HSA-70830 https://reactome.org/PathwayBrowser/#/R-HSA-70830 tiglyl-CoA + H2O <=> alpha-methyl-beta-hydroxybutyryl-CoA TAS Homo sapiens 15478 R-MMU-70800 https://reactome.org/PathwayBrowser/#/R-MMU-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Mus musculus 15478 R-RNO-70800 https://reactome.org/PathwayBrowser/#/R-RNO-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Rattus norvegicus 15478 R-SSC-70800 https://reactome.org/PathwayBrowser/#/R-SSC-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Sus scrofa 15478 R-XTR-70800 https://reactome.org/PathwayBrowser/#/R-XTR-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Xenopus tropicalis 15488 R-BTA-508308 https://reactome.org/PathwayBrowser/#/R-BTA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Bos taurus 15488 R-BTA-70773 https://reactome.org/PathwayBrowser/#/R-BTA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Bos taurus 15488 R-BTA-70785 https://reactome.org/PathwayBrowser/#/R-BTA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Bos taurus 15488 R-CEL-508308 https://reactome.org/PathwayBrowser/#/R-CEL-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Caenorhabditis elegans 15488 R-CEL-70773 https://reactome.org/PathwayBrowser/#/R-CEL-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Caenorhabditis elegans 15488 R-CEL-70785 https://reactome.org/PathwayBrowser/#/R-CEL-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Caenorhabditis elegans 15488 R-CFA-508308 https://reactome.org/PathwayBrowser/#/R-CFA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Canis familiaris 15488 R-CFA-70773 https://reactome.org/PathwayBrowser/#/R-CFA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Canis familiaris 15488 R-CFA-70785 https://reactome.org/PathwayBrowser/#/R-CFA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Canis familiaris 15488 R-DDI-508308 https://reactome.org/PathwayBrowser/#/R-DDI-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Dictyostelium discoideum 15488 R-DDI-70773 https://reactome.org/PathwayBrowser/#/R-DDI-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Dictyostelium discoideum 15488 R-DDI-70785 https://reactome.org/PathwayBrowser/#/R-DDI-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Dictyostelium discoideum 15488 R-DME-508308 https://reactome.org/PathwayBrowser/#/R-DME-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Drosophila melanogaster 15488 R-DME-70773 https://reactome.org/PathwayBrowser/#/R-DME-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Drosophila melanogaster 15488 R-DME-70785 https://reactome.org/PathwayBrowser/#/R-DME-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Drosophila melanogaster 15488 R-GGA-508308 https://reactome.org/PathwayBrowser/#/R-GGA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Gallus gallus 15488 R-GGA-70773 https://reactome.org/PathwayBrowser/#/R-GGA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Gallus gallus 15488 R-GGA-70785 https://reactome.org/PathwayBrowser/#/R-GGA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Gallus gallus 15488 R-HSA-508308 https://reactome.org/PathwayBrowser/#/R-HSA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] TAS Homo sapiens 15488 R-HSA-70773 https://reactome.org/PathwayBrowser/#/R-HSA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] TAS Homo sapiens 15488 R-HSA-70785 https://reactome.org/PathwayBrowser/#/R-HSA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA TAS Homo sapiens 15488 R-MMU-508308 https://reactome.org/PathwayBrowser/#/R-MMU-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Mus musculus 15488 R-MMU-70773 https://reactome.org/PathwayBrowser/#/R-MMU-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Mus musculus 15488 R-MMU-70785 https://reactome.org/PathwayBrowser/#/R-MMU-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Mus musculus 15488 R-PFA-70785 https://reactome.org/PathwayBrowser/#/R-PFA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Plasmodium falciparum 15488 R-RNO-508308 https://reactome.org/PathwayBrowser/#/R-RNO-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Rattus norvegicus 15488 R-RNO-70773 https://reactome.org/PathwayBrowser/#/R-RNO-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Rattus norvegicus 15488 R-RNO-70785 https://reactome.org/PathwayBrowser/#/R-RNO-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Rattus norvegicus 15488 R-SSC-508308 https://reactome.org/PathwayBrowser/#/R-SSC-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Sus scrofa 15488 R-SSC-70773 https://reactome.org/PathwayBrowser/#/R-SSC-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Sus scrofa 15488 R-SSC-70785 https://reactome.org/PathwayBrowser/#/R-SSC-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Sus scrofa 15488 R-XTR-508308 https://reactome.org/PathwayBrowser/#/R-XTR-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Xenopus tropicalis 15488 R-XTR-70773 https://reactome.org/PathwayBrowser/#/R-XTR-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Xenopus tropicalis 15488 R-XTR-70785 https://reactome.org/PathwayBrowser/#/R-XTR-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Xenopus tropicalis 15489 R-BTA-8874745 https://reactome.org/PathwayBrowser/#/R-BTA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Bos taurus 15489 R-CEL-8874745 https://reactome.org/PathwayBrowser/#/R-CEL-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Caenorhabditis elegans 15489 R-CFA-8874745 https://reactome.org/PathwayBrowser/#/R-CFA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Canis familiaris 15489 R-DME-8874745 https://reactome.org/PathwayBrowser/#/R-DME-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Drosophila melanogaster 15489 R-DRE-8874745 https://reactome.org/PathwayBrowser/#/R-DRE-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Danio rerio 15489 R-GGA-8874745 https://reactome.org/PathwayBrowser/#/R-GGA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Gallus gallus 15489 R-HSA-8874745 https://reactome.org/PathwayBrowser/#/R-HSA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH TAS Homo sapiens 15489 R-MMU-8874745 https://reactome.org/PathwayBrowser/#/R-MMU-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Mus musculus 15489 R-RNO-8874745 https://reactome.org/PathwayBrowser/#/R-RNO-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Rattus norvegicus 15489 R-SSC-8874745 https://reactome.org/PathwayBrowser/#/R-SSC-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Sus scrofa 15489 R-XTR-8874745 https://reactome.org/PathwayBrowser/#/R-XTR-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Xenopus tropicalis 15491 R-BTA-77303 https://reactome.org/PathwayBrowser/#/R-BTA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Bos taurus 15491 R-BTA-77304 https://reactome.org/PathwayBrowser/#/R-BTA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Bos taurus 15491 R-CEL-77303 https://reactome.org/PathwayBrowser/#/R-CEL-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Caenorhabditis elegans 15491 R-CEL-77304 https://reactome.org/PathwayBrowser/#/R-CEL-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Caenorhabditis elegans 15491 R-CFA-77303 https://reactome.org/PathwayBrowser/#/R-CFA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Canis familiaris 15491 R-CFA-77304 https://reactome.org/PathwayBrowser/#/R-CFA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Canis familiaris 15491 R-DME-77303 https://reactome.org/PathwayBrowser/#/R-DME-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Drosophila melanogaster 15491 R-DME-77304 https://reactome.org/PathwayBrowser/#/R-DME-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Drosophila melanogaster 15491 R-DRE-77303 https://reactome.org/PathwayBrowser/#/R-DRE-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Danio rerio 15491 R-DRE-77304 https://reactome.org/PathwayBrowser/#/R-DRE-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Danio rerio 15491 R-GGA-77303 https://reactome.org/PathwayBrowser/#/R-GGA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Gallus gallus 15491 R-GGA-77304 https://reactome.org/PathwayBrowser/#/R-GGA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Gallus gallus 15491 R-HSA-77303 https://reactome.org/PathwayBrowser/#/R-HSA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H TAS Homo sapiens 15491 R-HSA-77304 https://reactome.org/PathwayBrowser/#/R-HSA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA TAS Homo sapiens 15491 R-MMU-77303 https://reactome.org/PathwayBrowser/#/R-MMU-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Mus musculus 15491 R-MMU-77304 https://reactome.org/PathwayBrowser/#/R-MMU-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Mus musculus 15491 R-RNO-77303 https://reactome.org/PathwayBrowser/#/R-RNO-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Rattus norvegicus 15491 R-RNO-77304 https://reactome.org/PathwayBrowser/#/R-RNO-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Rattus norvegicus 15491 R-SSC-77303 https://reactome.org/PathwayBrowser/#/R-SSC-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Sus scrofa 15491 R-SSC-77304 https://reactome.org/PathwayBrowser/#/R-SSC-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Sus scrofa 15491 R-XTR-77303 https://reactome.org/PathwayBrowser/#/R-XTR-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Xenopus tropicalis 15491 R-XTR-77304 https://reactome.org/PathwayBrowser/#/R-XTR-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Xenopus tropicalis 15494 R-BTA-193369 https://reactome.org/PathwayBrowser/#/R-BTA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Bos taurus 15494 R-BTA-193407 https://reactome.org/PathwayBrowser/#/R-BTA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 15494 R-BTA-193424 https://reactome.org/PathwayBrowser/#/R-BTA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 15494 R-BTA-193452 https://reactome.org/PathwayBrowser/#/R-BTA-193452 Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA IEA Bos taurus 15494 R-CEL-193369 https://reactome.org/PathwayBrowser/#/R-CEL-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Caenorhabditis elegans 15494 R-CEL-193407 https://reactome.org/PathwayBrowser/#/R-CEL-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 15494 R-CEL-193424 https://reactome.org/PathwayBrowser/#/R-CEL-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 15494 R-CEL-193452 https://reactome.org/PathwayBrowser/#/R-CEL-193452 Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA IEA Caenorhabditis elegans 15494 R-CFA-193369 https://reactome.org/PathwayBrowser/#/R-CFA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Canis familiaris 15494 R-CFA-193407 https://reactome.org/PathwayBrowser/#/R-CFA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 15494 R-CFA-193424 https://reactome.org/PathwayBrowser/#/R-CFA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 15494 R-DDI-193369 https://reactome.org/PathwayBrowser/#/R-DDI-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Dictyostelium discoideum 15494 R-DME-193369 https://reactome.org/PathwayBrowser/#/R-DME-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Drosophila melanogaster 15494 R-DME-193407 https://reactome.org/PathwayBrowser/#/R-DME-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 15494 R-DME-193424 https://reactome.org/PathwayBrowser/#/R-DME-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 15494 R-DME-193452 https://reactome.org/PathwayBrowser/#/R-DME-193452 Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA IEA Drosophila melanogaster 15494 R-DRE-193407 https://reactome.org/PathwayBrowser/#/R-DRE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 15494 R-DRE-193452 https://reactome.org/PathwayBrowser/#/R-DRE-193452 Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA IEA Danio rerio 15494 R-GGA-193369 https://reactome.org/PathwayBrowser/#/R-GGA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Gallus gallus 15494 R-GGA-193407 https://reactome.org/PathwayBrowser/#/R-GGA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 15494 R-GGA-193424 https://reactome.org/PathwayBrowser/#/R-GGA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 15494 R-GGA-193452 https://reactome.org/PathwayBrowser/#/R-GGA-193452 Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA IEA Gallus gallus 15494 R-HSA-193369 https://reactome.org/PathwayBrowser/#/R-HSA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA TAS Homo sapiens 15494 R-HSA-193407 https://reactome.org/PathwayBrowser/#/R-HSA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 15494 R-HSA-193424 https://reactome.org/PathwayBrowser/#/R-HSA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 15494 R-HSA-193452 https://reactome.org/PathwayBrowser/#/R-HSA-193452 Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA TAS Homo sapiens 15494 R-HSA-193482 https://reactome.org/PathwayBrowser/#/R-HSA-193482 25(R) DHCA-CoA is translocated from the cytosol to the peroxisome TAS Homo sapiens 15494 R-MMU-193369 https://reactome.org/PathwayBrowser/#/R-MMU-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Mus musculus 15494 R-MMU-193407 https://reactome.org/PathwayBrowser/#/R-MMU-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 15494 R-MMU-193424 https://reactome.org/PathwayBrowser/#/R-MMU-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 15494 R-MMU-193452 https://reactome.org/PathwayBrowser/#/R-MMU-193452 Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA IEA Mus musculus 15494 R-RNO-193369 https://reactome.org/PathwayBrowser/#/R-RNO-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Rattus norvegicus 15494 R-RNO-193407 https://reactome.org/PathwayBrowser/#/R-RNO-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 15494 R-RNO-193424 https://reactome.org/PathwayBrowser/#/R-RNO-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 15494 R-RNO-193452 https://reactome.org/PathwayBrowser/#/R-RNO-193452 Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA IEA Rattus norvegicus 15494 R-SCE-193407 https://reactome.org/PathwayBrowser/#/R-SCE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 15494 R-SCE-193424 https://reactome.org/PathwayBrowser/#/R-SCE-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 15494 R-SSC-193369 https://reactome.org/PathwayBrowser/#/R-SSC-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Sus scrofa 15494 R-SSC-193407 https://reactome.org/PathwayBrowser/#/R-SSC-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 15494 R-SSC-193424 https://reactome.org/PathwayBrowser/#/R-SSC-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 15494 R-XTR-193369 https://reactome.org/PathwayBrowser/#/R-XTR-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Xenopus tropicalis 15494 R-XTR-193407 https://reactome.org/PathwayBrowser/#/R-XTR-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 15494 R-XTR-193424 https://reactome.org/PathwayBrowser/#/R-XTR-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 15494 R-XTR-193452 https://reactome.org/PathwayBrowser/#/R-XTR-193452 Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA IEA Xenopus tropicalis 15495 R-BTA-390224 https://reactome.org/PathwayBrowser/#/R-BTA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Bos taurus 15495 R-CFA-390224 https://reactome.org/PathwayBrowser/#/R-CFA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Canis familiaris 15495 R-DME-390224 https://reactome.org/PathwayBrowser/#/R-DME-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Drosophila melanogaster 15495 R-DRE-390224 https://reactome.org/PathwayBrowser/#/R-DRE-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Danio rerio 15495 R-GGA-390224 https://reactome.org/PathwayBrowser/#/R-GGA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Gallus gallus 15495 R-HSA-390224 https://reactome.org/PathwayBrowser/#/R-HSA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA TAS Homo sapiens 15495 R-HSA-390276 https://reactome.org/PathwayBrowser/#/R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA TAS Homo sapiens 15495 R-MMU-390224 https://reactome.org/PathwayBrowser/#/R-MMU-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Mus musculus 15495 R-RNO-390224 https://reactome.org/PathwayBrowser/#/R-RNO-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Rattus norvegicus 15508 R-BTA-2046094 https://reactome.org/PathwayBrowser/#/R-BTA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Bos taurus 15508 R-BTA-2046096 https://reactome.org/PathwayBrowser/#/R-BTA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Bos taurus 15508 R-CEL-2046094 https://reactome.org/PathwayBrowser/#/R-CEL-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Caenorhabditis elegans 15508 R-CEL-2046096 https://reactome.org/PathwayBrowser/#/R-CEL-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Caenorhabditis elegans 15508 R-CFA-2046094 https://reactome.org/PathwayBrowser/#/R-CFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Canis familiaris 15508 R-CFA-2046096 https://reactome.org/PathwayBrowser/#/R-CFA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Canis familiaris 15508 R-DDI-2046094 https://reactome.org/PathwayBrowser/#/R-DDI-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Dictyostelium discoideum 15508 R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster 15508 R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio 15508 R-DRE-2046096 https://reactome.org/PathwayBrowser/#/R-DRE-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Danio rerio 15508 R-GGA-2046094 https://reactome.org/PathwayBrowser/#/R-GGA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Gallus gallus 15508 R-GGA-2046096 https://reactome.org/PathwayBrowser/#/R-GGA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Gallus gallus 15508 R-HSA-2046094 https://reactome.org/PathwayBrowser/#/R-HSA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA TAS Homo sapiens 15508 R-HSA-2046096 https://reactome.org/PathwayBrowser/#/R-HSA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA TAS Homo sapiens 15508 R-MMU-2046094 https://reactome.org/PathwayBrowser/#/R-MMU-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Mus musculus 15508 R-MMU-2046096 https://reactome.org/PathwayBrowser/#/R-MMU-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Mus musculus 15508 R-PFA-2046094 https://reactome.org/PathwayBrowser/#/R-PFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Plasmodium falciparum 15508 R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus 15508 R-RNO-2046096 https://reactome.org/PathwayBrowser/#/R-RNO-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Rattus norvegicus 15508 R-SCE-2046094 https://reactome.org/PathwayBrowser/#/R-SCE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Saccharomyces cerevisiae 15508 R-SPO-2046094 https://reactome.org/PathwayBrowser/#/R-SPO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Schizosaccharomyces pombe 15508 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa 15508 R-SSC-2046096 https://reactome.org/PathwayBrowser/#/R-SSC-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Sus scrofa 15508 R-XTR-2046094 https://reactome.org/PathwayBrowser/#/R-XTR-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Xenopus tropicalis 15522 R-BTA-389611 https://reactome.org/PathwayBrowser/#/R-BTA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Bos taurus 15522 R-CEL-389611 https://reactome.org/PathwayBrowser/#/R-CEL-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Caenorhabditis elegans 15522 R-CFA-389611 https://reactome.org/PathwayBrowser/#/R-CFA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Canis familiaris 15522 R-DDI-389611 https://reactome.org/PathwayBrowser/#/R-DDI-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Dictyostelium discoideum 15522 R-DME-389611 https://reactome.org/PathwayBrowser/#/R-DME-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Drosophila melanogaster 15522 R-DRE-389611 https://reactome.org/PathwayBrowser/#/R-DRE-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Danio rerio 15522 R-GGA-389611 https://reactome.org/PathwayBrowser/#/R-GGA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Gallus gallus 15522 R-HSA-389580 https://reactome.org/PathwayBrowser/#/R-HSA-389580 formyl-CoA + H2O => formate + CoASH TAS Homo sapiens 15522 R-HSA-389611 https://reactome.org/PathwayBrowser/#/R-HSA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA TAS Homo sapiens 15522 R-MMU-389611 https://reactome.org/PathwayBrowser/#/R-MMU-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Mus musculus 15522 R-RNO-389611 https://reactome.org/PathwayBrowser/#/R-RNO-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Rattus norvegicus 15522 R-SCE-389611 https://reactome.org/PathwayBrowser/#/R-SCE-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Saccharomyces cerevisiae 15522 R-SPO-389611 https://reactome.org/PathwayBrowser/#/R-SPO-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Schizosaccharomyces pombe 15522 R-SSC-389611 https://reactome.org/PathwayBrowser/#/R-SSC-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Sus scrofa 15522 R-XTR-389611 https://reactome.org/PathwayBrowser/#/R-XTR-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Xenopus tropicalis 15530 R-BTA-2046096 https://reactome.org/PathwayBrowser/#/R-BTA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Bos taurus 15530 R-BTA-2046098 https://reactome.org/PathwayBrowser/#/R-BTA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Bos taurus 15530 R-CEL-2046096 https://reactome.org/PathwayBrowser/#/R-CEL-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Caenorhabditis elegans 15530 R-CFA-2046096 https://reactome.org/PathwayBrowser/#/R-CFA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Canis familiaris 15530 R-CFA-2046098 https://reactome.org/PathwayBrowser/#/R-CFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Canis familiaris 15530 R-DDI-2046098 https://reactome.org/PathwayBrowser/#/R-DDI-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Dictyostelium discoideum 15530 R-DRE-2046096 https://reactome.org/PathwayBrowser/#/R-DRE-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Danio rerio 15530 R-DRE-2046098 https://reactome.org/PathwayBrowser/#/R-DRE-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Danio rerio 15530 R-GGA-2046096 https://reactome.org/PathwayBrowser/#/R-GGA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Gallus gallus 15530 R-GGA-2046098 https://reactome.org/PathwayBrowser/#/R-GGA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Gallus gallus 15530 R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 15530 R-HSA-2046096 https://reactome.org/PathwayBrowser/#/R-HSA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA TAS Homo sapiens 15530 R-HSA-2046098 https://reactome.org/PathwayBrowser/#/R-HSA-2046098 Activation of linoleic acid to linoleoyl-CoA TAS Homo sapiens 15530 R-MMU-2046096 https://reactome.org/PathwayBrowser/#/R-MMU-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Mus musculus 15530 R-MMU-2046098 https://reactome.org/PathwayBrowser/#/R-MMU-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Mus musculus 15530 R-PFA-2046098 https://reactome.org/PathwayBrowser/#/R-PFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Plasmodium falciparum 15530 R-RNO-2046096 https://reactome.org/PathwayBrowser/#/R-RNO-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Rattus norvegicus 15530 R-RNO-2046098 https://reactome.org/PathwayBrowser/#/R-RNO-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Rattus norvegicus 15530 R-SSC-2046096 https://reactome.org/PathwayBrowser/#/R-SSC-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Sus scrofa 15530 R-SSC-2046098 https://reactome.org/PathwayBrowser/#/R-SSC-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Sus scrofa 15530 R-XTR-2046098 https://reactome.org/PathwayBrowser/#/R-XTR-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Xenopus tropicalis 15532 R-BTA-203611 https://reactome.org/PathwayBrowser/#/R-BTA-203611 N-myristoylation of eNOS IEA Bos taurus 15532 R-BTA-2534076 https://reactome.org/PathwayBrowser/#/R-BTA-2534076 Unknown Nat N-acylates Gly in Gnat1 TAS Bos taurus 15532 R-BTA-2534087 https://reactome.org/PathwayBrowser/#/R-BTA-2534087 NMT1/2 transfer MYS to GNAT1 IEA Bos taurus 15532 R-BTA-77274 https://reactome.org/PathwayBrowser/#/R-BTA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Bos taurus 15532 R-BTA-77304 https://reactome.org/PathwayBrowser/#/R-BTA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Bos taurus 15532 R-CEL-77304 https://reactome.org/PathwayBrowser/#/R-CEL-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Caenorhabditis elegans 15532 R-CFA-2534087 https://reactome.org/PathwayBrowser/#/R-CFA-2534087 NMT1/2 transfer MYS to GNAT1 IEA Canis familiaris 15532 R-CFA-77274 https://reactome.org/PathwayBrowser/#/R-CFA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Canis familiaris 15532 R-CFA-77304 https://reactome.org/PathwayBrowser/#/R-CFA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Canis familiaris 15532 R-DDI-203611 https://reactome.org/PathwayBrowser/#/R-DDI-203611 N-myristoylation of eNOS IEA Dictyostelium discoideum 15532 R-DDI-2534087 https://reactome.org/PathwayBrowser/#/R-DDI-2534087 NMT1/2 transfer MYS to GNAT1 IEA Dictyostelium discoideum 15532 R-DME-203611 https://reactome.org/PathwayBrowser/#/R-DME-203611 N-myristoylation of eNOS IEA Drosophila melanogaster 15532 R-DME-77304 https://reactome.org/PathwayBrowser/#/R-DME-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Drosophila melanogaster 15532 R-DRE-2534087 https://reactome.org/PathwayBrowser/#/R-DRE-2534087 NMT1/2 transfer MYS to GNAT1 IEA Danio rerio 15532 R-DRE-77274 https://reactome.org/PathwayBrowser/#/R-DRE-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Danio rerio 15532 R-DRE-77304 https://reactome.org/PathwayBrowser/#/R-DRE-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Danio rerio 15532 R-GGA-203611 https://reactome.org/PathwayBrowser/#/R-GGA-203611 N-myristoylation of eNOS IEA Gallus gallus 15532 R-GGA-77274 https://reactome.org/PathwayBrowser/#/R-GGA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Gallus gallus 15532 R-GGA-77304 https://reactome.org/PathwayBrowser/#/R-GGA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Gallus gallus 15532 R-HSA-162914 https://reactome.org/PathwayBrowser/#/R-HSA-162914 Myristoylation of Nef TAS Homo sapiens 15532 R-HSA-184392 https://reactome.org/PathwayBrowser/#/R-HSA-184392 N-myristoylation of GAG polyprotein by NMT2 TAS Homo sapiens 15532 R-HSA-203611 https://reactome.org/PathwayBrowser/#/R-HSA-203611 N-myristoylation of eNOS TAS Homo sapiens 15532 R-HSA-2534040 https://reactome.org/PathwayBrowser/#/R-HSA-2534040 Unknown NAT N-acylates Gly in GNAT1 IEA Homo sapiens 15532 R-HSA-2534087 https://reactome.org/PathwayBrowser/#/R-HSA-2534087 NMT1/2 transfer MYS to GNAT1 TAS Homo sapiens 15532 R-HSA-77274 https://reactome.org/PathwayBrowser/#/R-HSA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 TAS Homo sapiens 15532 R-HSA-77304 https://reactome.org/PathwayBrowser/#/R-HSA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA TAS Homo sapiens 15532 R-MMU-203611 https://reactome.org/PathwayBrowser/#/R-MMU-203611 N-myristoylation of eNOS IEA Mus musculus 15532 R-MMU-2534087 https://reactome.org/PathwayBrowser/#/R-MMU-2534087 NMT1/2 transfer MYS to GNAT1 IEA Mus musculus 15532 R-MMU-77274 https://reactome.org/PathwayBrowser/#/R-MMU-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Mus musculus 15532 R-MMU-77304 https://reactome.org/PathwayBrowser/#/R-MMU-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Mus musculus 15532 R-PFA-203611 https://reactome.org/PathwayBrowser/#/R-PFA-203611 N-myristoylation of eNOS IEA Plasmodium falciparum 15532 R-RNO-203611 https://reactome.org/PathwayBrowser/#/R-RNO-203611 N-myristoylation of eNOS IEA Rattus norvegicus 15532 R-RNO-2534087 https://reactome.org/PathwayBrowser/#/R-RNO-2534087 NMT1/2 transfer MYS to GNAT1 IEA Rattus norvegicus 15532 R-RNO-77274 https://reactome.org/PathwayBrowser/#/R-RNO-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 15532 R-RNO-77304 https://reactome.org/PathwayBrowser/#/R-RNO-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Rattus norvegicus 15532 R-SCE-203611 https://reactome.org/PathwayBrowser/#/R-SCE-203611 N-myristoylation of eNOS IEA Saccharomyces cerevisiae 15532 R-SCE-2534087 https://reactome.org/PathwayBrowser/#/R-SCE-2534087 NMT1/2 transfer MYS to GNAT1 IEA Saccharomyces cerevisiae 15532 R-SPO-203611 https://reactome.org/PathwayBrowser/#/R-SPO-203611 N-myristoylation of eNOS IEA Schizosaccharomyces pombe 15532 R-SPO-2534087 https://reactome.org/PathwayBrowser/#/R-SPO-2534087 NMT1/2 transfer MYS to GNAT1 IEA Schizosaccharomyces pombe 15532 R-SSC-203611 https://reactome.org/PathwayBrowser/#/R-SSC-203611 N-myristoylation of eNOS IEA Sus scrofa 15532 R-SSC-2534087 https://reactome.org/PathwayBrowser/#/R-SSC-2534087 NMT1/2 transfer MYS to GNAT1 IEA Sus scrofa 15532 R-SSC-77274 https://reactome.org/PathwayBrowser/#/R-SSC-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Sus scrofa 15532 R-SSC-77304 https://reactome.org/PathwayBrowser/#/R-SSC-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Sus scrofa 15532 R-XTR-2534087 https://reactome.org/PathwayBrowser/#/R-XTR-2534087 NMT1/2 transfer MYS to GNAT1 IEA Xenopus tropicalis 15532 R-XTR-77274 https://reactome.org/PathwayBrowser/#/R-XTR-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Xenopus tropicalis 15532 R-XTR-77304 https://reactome.org/PathwayBrowser/#/R-XTR-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Xenopus tropicalis 15533 R-BTA-77338 https://reactome.org/PathwayBrowser/#/R-BTA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Bos taurus 15533 R-BTA-77340 https://reactome.org/PathwayBrowser/#/R-BTA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Bos taurus 15533 R-CEL-77338 https://reactome.org/PathwayBrowser/#/R-CEL-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 15533 R-CEL-77340 https://reactome.org/PathwayBrowser/#/R-CEL-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Caenorhabditis elegans 15533 R-CFA-77338 https://reactome.org/PathwayBrowser/#/R-CFA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Canis familiaris 15533 R-CFA-77340 https://reactome.org/PathwayBrowser/#/R-CFA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Canis familiaris 15533 R-DME-77338 https://reactome.org/PathwayBrowser/#/R-DME-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 15533 R-DME-77340 https://reactome.org/PathwayBrowser/#/R-DME-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Drosophila melanogaster 15533 R-DRE-77340 https://reactome.org/PathwayBrowser/#/R-DRE-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Danio rerio 15533 R-GGA-77338 https://reactome.org/PathwayBrowser/#/R-GGA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Gallus gallus 15533 R-GGA-77340 https://reactome.org/PathwayBrowser/#/R-GGA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Gallus gallus 15533 R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA TAS Homo sapiens 15533 R-HSA-77338 https://reactome.org/PathwayBrowser/#/R-HSA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 TAS Homo sapiens 15533 R-HSA-77340 https://reactome.org/PathwayBrowser/#/R-HSA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA TAS Homo sapiens 15533 R-MMU-77338 https://reactome.org/PathwayBrowser/#/R-MMU-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Mus musculus 15533 R-MMU-77340 https://reactome.org/PathwayBrowser/#/R-MMU-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Mus musculus 15533 R-RNO-77338 https://reactome.org/PathwayBrowser/#/R-RNO-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 15533 R-RNO-77340 https://reactome.org/PathwayBrowser/#/R-RNO-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Rattus norvegicus 15533 R-SSC-77338 https://reactome.org/PathwayBrowser/#/R-SSC-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Sus scrofa 15533 R-SSC-77340 https://reactome.org/PathwayBrowser/#/R-SSC-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Sus scrofa 15533 R-XTR-77340 https://reactome.org/PathwayBrowser/#/R-XTR-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Xenopus tropicalis 15534 R-BTA-5690565 https://reactome.org/PathwayBrowser/#/R-BTA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Bos taurus 15534 R-BTA-8847579 https://reactome.org/PathwayBrowser/#/R-BTA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Bos taurus 15534 R-CEL-5690565 https://reactome.org/PathwayBrowser/#/R-CEL-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15534 R-CEL-8847579 https://reactome.org/PathwayBrowser/#/R-CEL-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15534 R-CFA-5690565 https://reactome.org/PathwayBrowser/#/R-CFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15534 R-CFA-8847579 https://reactome.org/PathwayBrowser/#/R-CFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15534 R-DDI-5690565 https://reactome.org/PathwayBrowser/#/R-DDI-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15534 R-DDI-8847579 https://reactome.org/PathwayBrowser/#/R-DDI-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15534 R-DME-5690565 https://reactome.org/PathwayBrowser/#/R-DME-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15534 R-DME-8847579 https://reactome.org/PathwayBrowser/#/R-DME-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15534 R-DRE-5690565 https://reactome.org/PathwayBrowser/#/R-DRE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Danio rerio 15534 R-GGA-5690565 https://reactome.org/PathwayBrowser/#/R-GGA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15534 R-GGA-8847579 https://reactome.org/PathwayBrowser/#/R-GGA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15534 R-HSA-5690565 https://reactome.org/PathwayBrowser/#/R-HSA-5690565 SCD desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15534 R-HSA-8847579 https://reactome.org/PathwayBrowser/#/R-HSA-8847579 SCD5 desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15534 R-MMU-5690565 https://reactome.org/PathwayBrowser/#/R-MMU-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Mus musculus 15534 R-PFA-5690565 https://reactome.org/PathwayBrowser/#/R-PFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15534 R-PFA-8847579 https://reactome.org/PathwayBrowser/#/R-PFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15534 R-RNO-5690565 https://reactome.org/PathwayBrowser/#/R-RNO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Rattus norvegicus 15534 R-SCE-5690565 https://reactome.org/PathwayBrowser/#/R-SCE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15534 R-SCE-8847579 https://reactome.org/PathwayBrowser/#/R-SCE-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15534 R-SPO-5690565 https://reactome.org/PathwayBrowser/#/R-SPO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15534 R-SPO-8847579 https://reactome.org/PathwayBrowser/#/R-SPO-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15534 R-SSC-5690565 https://reactome.org/PathwayBrowser/#/R-SSC-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15534 R-SSC-8847579 https://reactome.org/PathwayBrowser/#/R-SSC-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15534 R-XTR-5690565 https://reactome.org/PathwayBrowser/#/R-XTR-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Xenopus tropicalis 15538 R-BTA-389622 https://reactome.org/PathwayBrowser/#/R-BTA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 15538 R-BTA-389639 https://reactome.org/PathwayBrowser/#/R-BTA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Bos taurus 15538 R-BTA-6809810 https://reactome.org/PathwayBrowser/#/R-BTA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Bos taurus 15538 R-CEL-389622 https://reactome.org/PathwayBrowser/#/R-CEL-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 15538 R-CEL-389639 https://reactome.org/PathwayBrowser/#/R-CEL-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Caenorhabditis elegans 15538 R-CFA-389622 https://reactome.org/PathwayBrowser/#/R-CFA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 15538 R-CFA-389639 https://reactome.org/PathwayBrowser/#/R-CFA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Canis familiaris 15538 R-CFA-6809810 https://reactome.org/PathwayBrowser/#/R-CFA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Canis familiaris 15538 R-DDI-389639 https://reactome.org/PathwayBrowser/#/R-DDI-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Dictyostelium discoideum 15538 R-DME-389622 https://reactome.org/PathwayBrowser/#/R-DME-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 15538 R-DRE-389639 https://reactome.org/PathwayBrowser/#/R-DRE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Danio rerio 15538 R-DRE-6809810 https://reactome.org/PathwayBrowser/#/R-DRE-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Danio rerio 15538 R-GGA-389622 https://reactome.org/PathwayBrowser/#/R-GGA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 15538 R-GGA-389639 https://reactome.org/PathwayBrowser/#/R-GGA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Gallus gallus 15538 R-GGA-6809810 https://reactome.org/PathwayBrowser/#/R-GGA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Gallus gallus 15538 R-HSA-389622 https://reactome.org/PathwayBrowser/#/R-HSA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 15538 R-HSA-389639 https://reactome.org/PathwayBrowser/#/R-HSA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 TAS Homo sapiens 15538 R-HSA-6809810 https://reactome.org/PathwayBrowser/#/R-HSA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA TAS Homo sapiens 15538 R-MMU-389622 https://reactome.org/PathwayBrowser/#/R-MMU-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 15538 R-MMU-389639 https://reactome.org/PathwayBrowser/#/R-MMU-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Mus musculus 15538 R-MMU-6809810 https://reactome.org/PathwayBrowser/#/R-MMU-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Mus musculus 15538 R-RNO-389622 https://reactome.org/PathwayBrowser/#/R-RNO-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 15538 R-RNO-389639 https://reactome.org/PathwayBrowser/#/R-RNO-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Rattus norvegicus 15538 R-RNO-6809810 https://reactome.org/PathwayBrowser/#/R-RNO-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Rattus norvegicus 15538 R-SCE-389622 https://reactome.org/PathwayBrowser/#/R-SCE-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 15538 R-SCE-389639 https://reactome.org/PathwayBrowser/#/R-SCE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Saccharomyces cerevisiae 15538 R-SSC-389622 https://reactome.org/PathwayBrowser/#/R-SSC-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 15538 R-SSC-389639 https://reactome.org/PathwayBrowser/#/R-SSC-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Sus scrofa 15538 R-SSC-6809810 https://reactome.org/PathwayBrowser/#/R-SSC-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Sus scrofa 15538 R-XTR-389622 https://reactome.org/PathwayBrowser/#/R-XTR-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 15538 R-XTR-389639 https://reactome.org/PathwayBrowser/#/R-XTR-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Xenopus tropicalis 15539 R-BTA-192341 https://reactome.org/PathwayBrowser/#/R-BTA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Bos taurus 15539 R-BTA-193533 https://reactome.org/PathwayBrowser/#/R-BTA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Bos taurus 15539 R-BTA-2066781 https://reactome.org/PathwayBrowser/#/R-BTA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Bos taurus 15539 R-BTA-390224 https://reactome.org/PathwayBrowser/#/R-BTA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Bos taurus 15539 R-BTA-390284 https://reactome.org/PathwayBrowser/#/R-BTA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Bos taurus 15539 R-BTA-70844 https://reactome.org/PathwayBrowser/#/R-BTA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Bos taurus 15539 R-BTA-70893 https://reactome.org/PathwayBrowser/#/R-BTA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Bos taurus 15539 R-BTA-71031 https://reactome.org/PathwayBrowser/#/R-BTA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Bos taurus 15539 R-CEL-390284 https://reactome.org/PathwayBrowser/#/R-CEL-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Caenorhabditis elegans 15539 R-CEL-70844 https://reactome.org/PathwayBrowser/#/R-CEL-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Caenorhabditis elegans 15539 R-CEL-70893 https://reactome.org/PathwayBrowser/#/R-CEL-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 15539 R-CEL-71031 https://reactome.org/PathwayBrowser/#/R-CEL-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Caenorhabditis elegans 15539 R-CFA-192341 https://reactome.org/PathwayBrowser/#/R-CFA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Canis familiaris 15539 R-CFA-193533 https://reactome.org/PathwayBrowser/#/R-CFA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Canis familiaris 15539 R-CFA-2066781 https://reactome.org/PathwayBrowser/#/R-CFA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Canis familiaris 15539 R-CFA-390224 https://reactome.org/PathwayBrowser/#/R-CFA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Canis familiaris 15539 R-CFA-390284 https://reactome.org/PathwayBrowser/#/R-CFA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Canis familiaris 15539 R-CFA-70844 https://reactome.org/PathwayBrowser/#/R-CFA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Canis familiaris 15539 R-CFA-70893 https://reactome.org/PathwayBrowser/#/R-CFA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Canis familiaris 15539 R-CFA-71031 https://reactome.org/PathwayBrowser/#/R-CFA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Canis familiaris 15539 R-DDI-70844 https://reactome.org/PathwayBrowser/#/R-DDI-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Dictyostelium discoideum 15539 R-DDI-70893 https://reactome.org/PathwayBrowser/#/R-DDI-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 15539 R-DDI-71031 https://reactome.org/PathwayBrowser/#/R-DDI-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Dictyostelium discoideum 15539 R-DME-192341 https://reactome.org/PathwayBrowser/#/R-DME-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Drosophila melanogaster 15539 R-DME-193533 https://reactome.org/PathwayBrowser/#/R-DME-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Drosophila melanogaster 15539 R-DME-2066781 https://reactome.org/PathwayBrowser/#/R-DME-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Drosophila melanogaster 15539 R-DME-390224 https://reactome.org/PathwayBrowser/#/R-DME-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Drosophila melanogaster 15539 R-DME-390284 https://reactome.org/PathwayBrowser/#/R-DME-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Drosophila melanogaster 15539 R-DME-70844 https://reactome.org/PathwayBrowser/#/R-DME-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Drosophila melanogaster 15539 R-DME-70893 https://reactome.org/PathwayBrowser/#/R-DME-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 15539 R-DRE-192341 https://reactome.org/PathwayBrowser/#/R-DRE-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Danio rerio 15539 R-DRE-193533 https://reactome.org/PathwayBrowser/#/R-DRE-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Danio rerio 15539 R-DRE-2066781 https://reactome.org/PathwayBrowser/#/R-DRE-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Danio rerio 15539 R-DRE-390224 https://reactome.org/PathwayBrowser/#/R-DRE-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Danio rerio 15539 R-DRE-390284 https://reactome.org/PathwayBrowser/#/R-DRE-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Danio rerio 15539 R-DRE-70844 https://reactome.org/PathwayBrowser/#/R-DRE-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Danio rerio 15539 R-DRE-70893 https://reactome.org/PathwayBrowser/#/R-DRE-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Danio rerio 15539 R-DRE-71031 https://reactome.org/PathwayBrowser/#/R-DRE-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Danio rerio 15539 R-GGA-192341 https://reactome.org/PathwayBrowser/#/R-GGA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Gallus gallus 15539 R-GGA-193533 https://reactome.org/PathwayBrowser/#/R-GGA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Gallus gallus 15539 R-GGA-2066781 https://reactome.org/PathwayBrowser/#/R-GGA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Gallus gallus 15539 R-GGA-390224 https://reactome.org/PathwayBrowser/#/R-GGA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Gallus gallus 15539 R-GGA-390284 https://reactome.org/PathwayBrowser/#/R-GGA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Gallus gallus 15539 R-GGA-70844 https://reactome.org/PathwayBrowser/#/R-GGA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Gallus gallus 15539 R-GGA-70893 https://reactome.org/PathwayBrowser/#/R-GGA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Gallus gallus 15539 R-GGA-71031 https://reactome.org/PathwayBrowser/#/R-GGA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Gallus gallus 15539 R-HSA-192341 https://reactome.org/PathwayBrowser/#/R-HSA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA TAS Homo sapiens 15539 R-HSA-193533 https://reactome.org/PathwayBrowser/#/R-HSA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA TAS Homo sapiens 15539 R-HSA-2066781 https://reactome.org/PathwayBrowser/#/R-HSA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) TAS Homo sapiens 15539 R-HSA-390224 https://reactome.org/PathwayBrowser/#/R-HSA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA TAS Homo sapiens 15539 R-HSA-390276 https://reactome.org/PathwayBrowser/#/R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA TAS Homo sapiens 15539 R-HSA-390284 https://reactome.org/PathwayBrowser/#/R-HSA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH TAS Homo sapiens 15539 R-HSA-70844 https://reactome.org/PathwayBrowser/#/R-HSA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA TAS Homo sapiens 15539 R-HSA-70893 https://reactome.org/PathwayBrowser/#/R-HSA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ TAS Homo sapiens 15539 R-HSA-71031 https://reactome.org/PathwayBrowser/#/R-HSA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate TAS Homo sapiens 15539 R-MMU-192341 https://reactome.org/PathwayBrowser/#/R-MMU-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Mus musculus 15539 R-MMU-193533 https://reactome.org/PathwayBrowser/#/R-MMU-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Mus musculus 15539 R-MMU-2066781 https://reactome.org/PathwayBrowser/#/R-MMU-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Mus musculus 15539 R-MMU-390224 https://reactome.org/PathwayBrowser/#/R-MMU-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Mus musculus 15539 R-MMU-390284 https://reactome.org/PathwayBrowser/#/R-MMU-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Mus musculus 15539 R-MMU-70844 https://reactome.org/PathwayBrowser/#/R-MMU-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Mus musculus 15539 R-MMU-70893 https://reactome.org/PathwayBrowser/#/R-MMU-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Mus musculus 15539 R-MMU-71031 https://reactome.org/PathwayBrowser/#/R-MMU-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Mus musculus 15539 R-PFA-70844 https://reactome.org/PathwayBrowser/#/R-PFA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Plasmodium falciparum 15539 R-RNO-192341 https://reactome.org/PathwayBrowser/#/R-RNO-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Rattus norvegicus 15539 R-RNO-193533 https://reactome.org/PathwayBrowser/#/R-RNO-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Rattus norvegicus 15539 R-RNO-2066781 https://reactome.org/PathwayBrowser/#/R-RNO-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Rattus norvegicus 15539 R-RNO-390224 https://reactome.org/PathwayBrowser/#/R-RNO-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Rattus norvegicus 15539 R-RNO-390284 https://reactome.org/PathwayBrowser/#/R-RNO-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Rattus norvegicus 15539 R-RNO-70844 https://reactome.org/PathwayBrowser/#/R-RNO-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Rattus norvegicus 15539 R-RNO-70893 https://reactome.org/PathwayBrowser/#/R-RNO-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 15539 R-RNO-71031 https://reactome.org/PathwayBrowser/#/R-RNO-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Rattus norvegicus 15539 R-SSC-390284 https://reactome.org/PathwayBrowser/#/R-SSC-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Sus scrofa 15539 R-SSC-70844 https://reactome.org/PathwayBrowser/#/R-SSC-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Sus scrofa 15539 R-SSC-70893 https://reactome.org/PathwayBrowser/#/R-SSC-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Sus scrofa 15539 R-SSC-71031 https://reactome.org/PathwayBrowser/#/R-SSC-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Sus scrofa 15539 R-XTR-390284 https://reactome.org/PathwayBrowser/#/R-XTR-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Xenopus tropicalis 15539 R-XTR-70844 https://reactome.org/PathwayBrowser/#/R-XTR-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Xenopus tropicalis 15539 R-XTR-70893 https://reactome.org/PathwayBrowser/#/R-XTR-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 15539 R-XTR-71031 https://reactome.org/PathwayBrowser/#/R-XTR-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Xenopus tropicalis 15544 R-BTA-879528 https://reactome.org/PathwayBrowser/#/R-BTA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Bos taurus 15544 R-BTA-879584 https://reactome.org/PathwayBrowser/#/R-BTA-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Bos taurus 15544 R-CEL-879528 https://reactome.org/PathwayBrowser/#/R-CEL-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Caenorhabditis elegans 15544 R-CFA-879528 https://reactome.org/PathwayBrowser/#/R-CFA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Canis familiaris 15544 R-CFA-879584 https://reactome.org/PathwayBrowser/#/R-CFA-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Canis familiaris 15544 R-DME-879528 https://reactome.org/PathwayBrowser/#/R-DME-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Drosophila melanogaster 15544 R-GGA-879528 https://reactome.org/PathwayBrowser/#/R-GGA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Gallus gallus 15544 R-GGA-879584 https://reactome.org/PathwayBrowser/#/R-GGA-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Gallus gallus 15544 R-HSA-5661188 https://reactome.org/PathwayBrowser/#/R-HSA-5661188 Defective SLCO2A1 does not transport PGT substrates from extracellular region to cytosol TAS Homo sapiens 15544 R-HSA-879528 https://reactome.org/PathwayBrowser/#/R-HSA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol TAS Homo sapiens 15544 R-HSA-879584 https://reactome.org/PathwayBrowser/#/R-HSA-879584 SLCO3A1 isoform 1 has abroad substrate specificity TAS Homo sapiens 15544 R-MMU-879528 https://reactome.org/PathwayBrowser/#/R-MMU-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Mus musculus 15544 R-MMU-879584 https://reactome.org/PathwayBrowser/#/R-MMU-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Mus musculus 15544 R-RNO-879528 https://reactome.org/PathwayBrowser/#/R-RNO-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Rattus norvegicus 15544 R-RNO-879584 https://reactome.org/PathwayBrowser/#/R-RNO-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Rattus norvegicus 15544 R-SSC-879528 https://reactome.org/PathwayBrowser/#/R-SSC-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Sus scrofa 15544 R-SSC-879584 https://reactome.org/PathwayBrowser/#/R-SSC-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Sus scrofa 15544 R-XTR-879528 https://reactome.org/PathwayBrowser/#/R-XTR-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Xenopus tropicalis 15547 R-HSA-2161662 https://reactome.org/PathwayBrowser/#/R-HSA-2161662 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD IEA Homo sapiens 15547 R-HSA-2161692 https://reactome.org/PathwayBrowser/#/R-HSA-2161692 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1 IEA Homo sapiens 15547 R-MMU-2161638 https://reactome.org/PathwayBrowser/#/R-MMU-2161638 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by Ptgr2 TAS Mus musculus 15547 R-OCU-2161568 https://reactome.org/PathwayBrowser/#/R-OCU-2161568 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD TAS Oryctolagus cuniculus 15550 R-HSA-2161692 https://reactome.org/PathwayBrowser/#/R-HSA-2161692 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1 IEA Homo sapiens 15550 R-MMU-2161638 https://reactome.org/PathwayBrowser/#/R-MMU-2161638 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by Ptgr2 TAS Mus musculus 15551 R-BTA-2161651 https://reactome.org/PathwayBrowser/#/R-BTA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Bos taurus 15551 R-BTA-2161660 https://reactome.org/PathwayBrowser/#/R-BTA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Bos taurus 15551 R-BTA-265295 https://reactome.org/PathwayBrowser/#/R-BTA-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Bos taurus 15551 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 15551 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15551 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 15551 R-BTA-391933 https://reactome.org/PathwayBrowser/#/R-BTA-391933 EP3 receptor can bind PGE2 IEA Bos taurus 15551 R-BTA-391936 https://reactome.org/PathwayBrowser/#/R-BTA-391936 EP1 receptor can bind PGE2 IEA Bos taurus 15551 R-BTA-391940 https://reactome.org/PathwayBrowser/#/R-BTA-391940 EP2 and EP4 receptors can bind PGE2 IEA Bos taurus 15551 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15551 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15551 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 15551 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 15551 R-BTA-879528 https://reactome.org/PathwayBrowser/#/R-BTA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Bos taurus 15551 R-BTA-879584 https://reactome.org/PathwayBrowser/#/R-BTA-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Bos taurus 15551 R-CEL-265295 https://reactome.org/PathwayBrowser/#/R-CEL-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Caenorhabditis elegans 15551 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15551 R-CEL-879528 https://reactome.org/PathwayBrowser/#/R-CEL-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Caenorhabditis elegans 15551 R-CFA-2161651 https://reactome.org/PathwayBrowser/#/R-CFA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Canis familiaris 15551 R-CFA-2161660 https://reactome.org/PathwayBrowser/#/R-CFA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Canis familiaris 15551 R-CFA-265295 https://reactome.org/PathwayBrowser/#/R-CFA-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Canis familiaris 15551 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15551 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 15551 R-CFA-391933 https://reactome.org/PathwayBrowser/#/R-CFA-391933 EP3 receptor can bind PGE2 IEA Canis familiaris 15551 R-CFA-391936 https://reactome.org/PathwayBrowser/#/R-CFA-391936 EP1 receptor can bind PGE2 IEA Canis familiaris 15551 R-CFA-391940 https://reactome.org/PathwayBrowser/#/R-CFA-391940 EP2 and EP4 receptors can bind PGE2 IEA Canis familiaris 15551 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15551 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15551 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 15551 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 15551 R-CFA-879528 https://reactome.org/PathwayBrowser/#/R-CFA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Canis familiaris 15551 R-CFA-879584 https://reactome.org/PathwayBrowser/#/R-CFA-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Canis familiaris 15551 R-DDI-265295 https://reactome.org/PathwayBrowser/#/R-DDI-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Dictyostelium discoideum 15551 R-DME-2161660 https://reactome.org/PathwayBrowser/#/R-DME-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Drosophila melanogaster 15551 R-DME-265295 https://reactome.org/PathwayBrowser/#/R-DME-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Drosophila melanogaster 15551 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 15551 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 15551 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 15551 R-DME-391933 https://reactome.org/PathwayBrowser/#/R-DME-391933 EP3 receptor can bind PGE2 IEA Drosophila melanogaster 15551 R-DME-391936 https://reactome.org/PathwayBrowser/#/R-DME-391936 EP1 receptor can bind PGE2 IEA Drosophila melanogaster 15551 R-DME-391940 https://reactome.org/PathwayBrowser/#/R-DME-391940 EP2 and EP4 receptors can bind PGE2 IEA Drosophila melanogaster 15551 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 15551 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15551 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 15551 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 15551 R-DME-879528 https://reactome.org/PathwayBrowser/#/R-DME-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Drosophila melanogaster 15551 R-DRE-2161651 https://reactome.org/PathwayBrowser/#/R-DRE-2161651 PGE2 is converted to PGF2a by CBR1 IEA Danio rerio 15551 R-DRE-2161660 https://reactome.org/PathwayBrowser/#/R-DRE-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Danio rerio 15551 R-DRE-265295 https://reactome.org/PathwayBrowser/#/R-DRE-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Danio rerio 15551 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 15551 R-DRE-391936 https://reactome.org/PathwayBrowser/#/R-DRE-391936 EP1 receptor can bind PGE2 IEA Danio rerio 15551 R-DRE-391940 https://reactome.org/PathwayBrowser/#/R-DRE-391940 EP2 and EP4 receptors can bind PGE2 IEA Danio rerio 15551 R-GGA-2161651 https://reactome.org/PathwayBrowser/#/R-GGA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Gallus gallus 15551 R-GGA-2161660 https://reactome.org/PathwayBrowser/#/R-GGA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Gallus gallus 15551 R-GGA-265295 https://reactome.org/PathwayBrowser/#/R-GGA-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Gallus gallus 15551 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 15551 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 15551 R-GGA-391933 https://reactome.org/PathwayBrowser/#/R-GGA-391933 EP3 receptor can bind PGE2 IEA Gallus gallus 15551 R-GGA-391940 https://reactome.org/PathwayBrowser/#/R-GGA-391940 EP2 and EP4 receptors can bind PGE2 IEA Gallus gallus 15551 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15551 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 15551 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 15551 R-GGA-879528 https://reactome.org/PathwayBrowser/#/R-GGA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Gallus gallus 15551 R-GGA-879584 https://reactome.org/PathwayBrowser/#/R-GGA-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Gallus gallus 15551 R-HSA-2161651 https://reactome.org/PathwayBrowser/#/R-HSA-2161651 PGE2 is converted to PGF2a by CBR1 TAS Homo sapiens 15551 R-HSA-2161659 https://reactome.org/PathwayBrowser/#/R-HSA-2161659 PGE2 is dehydrated to PGA2 TAS Homo sapiens 15551 R-HSA-2161660 https://reactome.org/PathwayBrowser/#/R-HSA-2161660 PGH2 is isomerised to PGE2 by PTGES TAS Homo sapiens 15551 R-HSA-2161662 https://reactome.org/PathwayBrowser/#/R-HSA-2161662 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD IEA Homo sapiens 15551 R-HSA-265295 https://reactome.org/PathwayBrowser/#/R-HSA-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 TAS Homo sapiens 15551 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 15551 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15551 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 15551 R-HSA-391933 https://reactome.org/PathwayBrowser/#/R-HSA-391933 EP3 receptor can bind PGE2 TAS Homo sapiens 15551 R-HSA-391936 https://reactome.org/PathwayBrowser/#/R-HSA-391936 EP1 receptor can bind PGE2 TAS Homo sapiens 15551 R-HSA-391940 https://reactome.org/PathwayBrowser/#/R-HSA-391940 EP2 and EP4 receptors can bind PGE2 TAS Homo sapiens 15551 R-HSA-5661188 https://reactome.org/PathwayBrowser/#/R-HSA-5661188 Defective SLCO2A1 does not transport PGT substrates from extracellular region to cytosol TAS Homo sapiens 15551 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 15551 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 15551 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15551 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15551 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 15551 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 15551 R-HSA-879528 https://reactome.org/PathwayBrowser/#/R-HSA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol TAS Homo sapiens 15551 R-HSA-879584 https://reactome.org/PathwayBrowser/#/R-HSA-879584 SLCO3A1 isoform 1 has abroad substrate specificity TAS Homo sapiens 15551 R-MMU-2161651 https://reactome.org/PathwayBrowser/#/R-MMU-2161651 PGE2 is converted to PGF2a by CBR1 IEA Mus musculus 15551 R-MMU-2161660 https://reactome.org/PathwayBrowser/#/R-MMU-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Mus musculus 15551 R-MMU-265295 https://reactome.org/PathwayBrowser/#/R-MMU-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Mus musculus 15551 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 15551 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15551 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 15551 R-MMU-391933 https://reactome.org/PathwayBrowser/#/R-MMU-391933 EP3 receptor can bind PGE2 IEA Mus musculus 15551 R-MMU-391936 https://reactome.org/PathwayBrowser/#/R-MMU-391936 EP1 receptor can bind PGE2 IEA Mus musculus 15551 R-MMU-391940 https://reactome.org/PathwayBrowser/#/R-MMU-391940 EP2 and EP4 receptors can bind PGE2 IEA Mus musculus 15551 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15551 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15551 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 15551 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 15551 R-MMU-879528 https://reactome.org/PathwayBrowser/#/R-MMU-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Mus musculus 15551 R-MMU-879584 https://reactome.org/PathwayBrowser/#/R-MMU-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Mus musculus 15551 R-OCU-2161568 https://reactome.org/PathwayBrowser/#/R-OCU-2161568 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD TAS Oryctolagus cuniculus 15551 R-PFA-265295 https://reactome.org/PathwayBrowser/#/R-PFA-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Plasmodium falciparum 15551 R-RNO-2161651 https://reactome.org/PathwayBrowser/#/R-RNO-2161651 PGE2 is converted to PGF2a by CBR1 IEA Rattus norvegicus 15551 R-RNO-2161660 https://reactome.org/PathwayBrowser/#/R-RNO-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Rattus norvegicus 15551 R-RNO-265295 https://reactome.org/PathwayBrowser/#/R-RNO-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Rattus norvegicus 15551 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15551 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 15551 R-RNO-391933 https://reactome.org/PathwayBrowser/#/R-RNO-391933 EP3 receptor can bind PGE2 IEA Rattus norvegicus 15551 R-RNO-391936 https://reactome.org/PathwayBrowser/#/R-RNO-391936 EP1 receptor can bind PGE2 IEA Rattus norvegicus 15551 R-RNO-391940 https://reactome.org/PathwayBrowser/#/R-RNO-391940 EP2 and EP4 receptors can bind PGE2 IEA Rattus norvegicus 15551 R-RNO-879528 https://reactome.org/PathwayBrowser/#/R-RNO-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Rattus norvegicus 15551 R-RNO-879584 https://reactome.org/PathwayBrowser/#/R-RNO-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Rattus norvegicus 15551 R-SCE-265295 https://reactome.org/PathwayBrowser/#/R-SCE-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Saccharomyces cerevisiae 15551 R-SPO-265295 https://reactome.org/PathwayBrowser/#/R-SPO-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Schizosaccharomyces pombe 15551 R-SSC-2161651 https://reactome.org/PathwayBrowser/#/R-SSC-2161651 PGE2 is converted to PGF2a by CBR1 IEA Sus scrofa 15551 R-SSC-2161660 https://reactome.org/PathwayBrowser/#/R-SSC-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Sus scrofa 15551 R-SSC-265295 https://reactome.org/PathwayBrowser/#/R-SSC-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Sus scrofa 15551 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 15551 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15551 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 15551 R-SSC-391933 https://reactome.org/PathwayBrowser/#/R-SSC-391933 EP3 receptor can bind PGE2 IEA Sus scrofa 15551 R-SSC-391936 https://reactome.org/PathwayBrowser/#/R-SSC-391936 EP1 receptor can bind PGE2 IEA Sus scrofa 15551 R-SSC-391940 https://reactome.org/PathwayBrowser/#/R-SSC-391940 EP2 and EP4 receptors can bind PGE2 IEA Sus scrofa 15551 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15551 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15551 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 15551 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 15551 R-SSC-879528 https://reactome.org/PathwayBrowser/#/R-SSC-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Sus scrofa 15551 R-SSC-879584 https://reactome.org/PathwayBrowser/#/R-SSC-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Sus scrofa 15551 R-XTR-2161651 https://reactome.org/PathwayBrowser/#/R-XTR-2161651 PGE2 is converted to PGF2a by CBR1 IEA Xenopus tropicalis 15551 R-XTR-2161660 https://reactome.org/PathwayBrowser/#/R-XTR-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Xenopus tropicalis 15551 R-XTR-265295 https://reactome.org/PathwayBrowser/#/R-XTR-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Xenopus tropicalis 15551 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 15551 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 15551 R-XTR-391933 https://reactome.org/PathwayBrowser/#/R-XTR-391933 EP3 receptor can bind PGE2 IEA Xenopus tropicalis 15551 R-XTR-391936 https://reactome.org/PathwayBrowser/#/R-XTR-391936 EP1 receptor can bind PGE2 IEA Xenopus tropicalis 15551 R-XTR-391940 https://reactome.org/PathwayBrowser/#/R-XTR-391940 EP2 and EP4 receptors can bind PGE2 IEA Xenopus tropicalis 15551 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 15551 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15551 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 15551 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 15551 R-XTR-879528 https://reactome.org/PathwayBrowser/#/R-XTR-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Xenopus tropicalis 15552 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 15552 R-BTA-391942 https://reactome.org/PathwayBrowser/#/R-BTA-391942 IP receptor can bind prostacyclin IEA Bos taurus 15552 R-BTA-392870 https://reactome.org/PathwayBrowser/#/R-BTA-392870 Gs activation by prostacyclin receptor IEA Bos taurus 15552 R-BTA-76496 https://reactome.org/PathwayBrowser/#/R-BTA-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Bos taurus 15552 R-CFA-391942 https://reactome.org/PathwayBrowser/#/R-CFA-391942 IP receptor can bind prostacyclin IEA Canis familiaris 15552 R-CFA-392870 https://reactome.org/PathwayBrowser/#/R-CFA-392870 Gs activation by prostacyclin receptor IEA Canis familiaris 15552 R-CFA-76496 https://reactome.org/PathwayBrowser/#/R-CFA-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Canis familiaris 15552 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 15552 R-DME-391942 https://reactome.org/PathwayBrowser/#/R-DME-391942 IP receptor can bind prostacyclin IEA Drosophila melanogaster 15552 R-DME-392870 https://reactome.org/PathwayBrowser/#/R-DME-392870 Gs activation by prostacyclin receptor IEA Drosophila melanogaster 15552 R-DRE-391942 https://reactome.org/PathwayBrowser/#/R-DRE-391942 IP receptor can bind prostacyclin IEA Danio rerio 15552 R-DRE-76496 https://reactome.org/PathwayBrowser/#/R-DRE-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Danio rerio 15552 R-HSA-2161619 https://reactome.org/PathwayBrowser/#/R-HSA-2161619 PGI2 is hydrolysed to 6k-PGF1a TAS Homo sapiens 15552 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 15552 R-HSA-391942 https://reactome.org/PathwayBrowser/#/R-HSA-391942 IP receptor can bind prostacyclin TAS Homo sapiens 15552 R-HSA-392852 https://reactome.org/PathwayBrowser/#/R-HSA-392852 Activated prostacyclin receptor binds G-protein Gs TAS Homo sapiens 15552 R-HSA-392870 https://reactome.org/PathwayBrowser/#/R-HSA-392870 Gs activation by prostacyclin receptor TAS Homo sapiens 15552 R-HSA-392874 https://reactome.org/PathwayBrowser/#/R-HSA-392874 Dissociation of the Prostacyclin receptor:Gs complex IEA Homo sapiens 15552 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 15552 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 15552 R-HSA-76496 https://reactome.org/PathwayBrowser/#/R-HSA-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 TAS Homo sapiens 15552 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 15552 R-MMU-391942 https://reactome.org/PathwayBrowser/#/R-MMU-391942 IP receptor can bind prostacyclin IEA Mus musculus 15552 R-MMU-392870 https://reactome.org/PathwayBrowser/#/R-MMU-392870 Gs activation by prostacyclin receptor IEA Mus musculus 15552 R-MMU-76496 https://reactome.org/PathwayBrowser/#/R-MMU-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Mus musculus 15552 R-RNO-391942 https://reactome.org/PathwayBrowser/#/R-RNO-391942 IP receptor can bind prostacyclin IEA Rattus norvegicus 15552 R-RNO-76496 https://reactome.org/PathwayBrowser/#/R-RNO-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Rattus norvegicus 15552 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 15552 R-SSC-391942 https://reactome.org/PathwayBrowser/#/R-SSC-391942 IP receptor can bind prostacyclin IEA Sus scrofa 15552 R-SSC-392870 https://reactome.org/PathwayBrowser/#/R-SSC-392870 Gs activation by prostacyclin receptor IEA Sus scrofa 15552 R-SSC-76496 https://reactome.org/PathwayBrowser/#/R-SSC-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Sus scrofa 15552 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 15552 R-XTR-391942 https://reactome.org/PathwayBrowser/#/R-XTR-391942 IP receptor can bind prostacyclin IEA Xenopus tropicalis 15552 R-XTR-392870 https://reactome.org/PathwayBrowser/#/R-XTR-392870 Gs activation by prostacyclin receptor IEA Xenopus tropicalis 15552 R-XTR-76496 https://reactome.org/PathwayBrowser/#/R-XTR-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Xenopus tropicalis 15553 R-BTA-2161549 https://reactome.org/PathwayBrowser/#/R-BTA-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Bos taurus 15553 R-BTA-2161651 https://reactome.org/PathwayBrowser/#/R-BTA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Bos taurus 15553 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15553 R-BTA-416929 https://reactome.org/PathwayBrowser/#/R-BTA-416929 PTGFR binds PGF2a IEA Bos taurus 15553 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15553 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15553 R-BTA-879528 https://reactome.org/PathwayBrowser/#/R-BTA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Bos taurus 15553 R-CEL-2161549 https://reactome.org/PathwayBrowser/#/R-CEL-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Caenorhabditis elegans 15553 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15553 R-CEL-879528 https://reactome.org/PathwayBrowser/#/R-CEL-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Caenorhabditis elegans 15553 R-CFA-2161651 https://reactome.org/PathwayBrowser/#/R-CFA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Canis familiaris 15553 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15553 R-CFA-416929 https://reactome.org/PathwayBrowser/#/R-CFA-416929 PTGFR binds PGF2a IEA Canis familiaris 15553 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15553 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15553 R-CFA-879528 https://reactome.org/PathwayBrowser/#/R-CFA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Canis familiaris 15553 R-DDI-2161549 https://reactome.org/PathwayBrowser/#/R-DDI-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Dictyostelium discoideum 15553 R-DME-2161549 https://reactome.org/PathwayBrowser/#/R-DME-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Drosophila melanogaster 15553 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 15553 R-DME-416929 https://reactome.org/PathwayBrowser/#/R-DME-416929 PTGFR binds PGF2a IEA Drosophila melanogaster 15553 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 15553 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15553 R-DME-879528 https://reactome.org/PathwayBrowser/#/R-DME-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Drosophila melanogaster 15553 R-DRE-2161651 https://reactome.org/PathwayBrowser/#/R-DRE-2161651 PGE2 is converted to PGF2a by CBR1 IEA Danio rerio 15553 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 15553 R-DRE-416929 https://reactome.org/PathwayBrowser/#/R-DRE-416929 PTGFR binds PGF2a IEA Danio rerio 15553 R-GGA-2161651 https://reactome.org/PathwayBrowser/#/R-GGA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Gallus gallus 15553 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 15553 R-GGA-416929 https://reactome.org/PathwayBrowser/#/R-GGA-416929 PTGFR binds PGF2a IEA Gallus gallus 15553 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 15553 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15553 R-GGA-879528 https://reactome.org/PathwayBrowser/#/R-GGA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Gallus gallus 15553 R-HSA-2161549 https://reactome.org/PathwayBrowser/#/R-HSA-2161549 PGH2 is reduced to PGF2a by AKR1C3 TAS Homo sapiens 15553 R-HSA-2161612 https://reactome.org/PathwayBrowser/#/R-HSA-2161612 PGH2 is reduced to PGF2a by FAM213B IEA Homo sapiens 15553 R-HSA-2161651 https://reactome.org/PathwayBrowser/#/R-HSA-2161651 PGE2 is converted to PGF2a by CBR1 TAS Homo sapiens 15553 R-HSA-2161662 https://reactome.org/PathwayBrowser/#/R-HSA-2161662 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD IEA Homo sapiens 15553 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15553 R-HSA-416929 https://reactome.org/PathwayBrowser/#/R-HSA-416929 PTGFR binds PGF2a TAS Homo sapiens 15553 R-HSA-5661188 https://reactome.org/PathwayBrowser/#/R-HSA-5661188 Defective SLCO2A1 does not transport PGT substrates from extracellular region to cytosol TAS Homo sapiens 15553 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15553 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15553 R-HSA-879528 https://reactome.org/PathwayBrowser/#/R-HSA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol TAS Homo sapiens 15553 R-MMU-2161549 https://reactome.org/PathwayBrowser/#/R-MMU-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Mus musculus 15553 R-MMU-2161651 https://reactome.org/PathwayBrowser/#/R-MMU-2161651 PGE2 is converted to PGF2a by CBR1 IEA Mus musculus 15553 R-MMU-2161718 https://reactome.org/PathwayBrowser/#/R-MMU-2161718 PGH2 is reduced to PGF2a by Fam213b TAS Mus musculus 15553 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15553 R-MMU-416929 https://reactome.org/PathwayBrowser/#/R-MMU-416929 PTGFR binds PGF2a IEA Mus musculus 15553 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15553 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15553 R-MMU-879528 https://reactome.org/PathwayBrowser/#/R-MMU-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Mus musculus 15553 R-OCU-2161568 https://reactome.org/PathwayBrowser/#/R-OCU-2161568 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD TAS Oryctolagus cuniculus 15553 R-RNO-2161549 https://reactome.org/PathwayBrowser/#/R-RNO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Rattus norvegicus 15553 R-RNO-2161651 https://reactome.org/PathwayBrowser/#/R-RNO-2161651 PGE2 is converted to PGF2a by CBR1 IEA Rattus norvegicus 15553 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15553 R-RNO-416929 https://reactome.org/PathwayBrowser/#/R-RNO-416929 PTGFR binds PGF2a IEA Rattus norvegicus 15553 R-RNO-879528 https://reactome.org/PathwayBrowser/#/R-RNO-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Rattus norvegicus 15553 R-SCE-2161549 https://reactome.org/PathwayBrowser/#/R-SCE-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Saccharomyces cerevisiae 15553 R-SPO-2161549 https://reactome.org/PathwayBrowser/#/R-SPO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Schizosaccharomyces pombe 15553 R-SSC-2161549 https://reactome.org/PathwayBrowser/#/R-SSC-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Sus scrofa 15553 R-SSC-2161651 https://reactome.org/PathwayBrowser/#/R-SSC-2161651 PGE2 is converted to PGF2a by CBR1 IEA Sus scrofa 15553 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15553 R-SSC-416929 https://reactome.org/PathwayBrowser/#/R-SSC-416929 PTGFR binds PGF2a IEA Sus scrofa 15553 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15553 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15553 R-SSC-879528 https://reactome.org/PathwayBrowser/#/R-SSC-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Sus scrofa 15553 R-XTR-2161549 https://reactome.org/PathwayBrowser/#/R-XTR-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Xenopus tropicalis 15553 R-XTR-2161651 https://reactome.org/PathwayBrowser/#/R-XTR-2161651 PGE2 is converted to PGF2a by CBR1 IEA Xenopus tropicalis 15553 R-XTR-416929 https://reactome.org/PathwayBrowser/#/R-XTR-416929 PTGFR binds PGF2a IEA Xenopus tropicalis 15553 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 15553 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15553 R-XTR-879528 https://reactome.org/PathwayBrowser/#/R-XTR-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Xenopus tropicalis 15554 R-BTA-140359 https://reactome.org/PathwayBrowser/#/R-BTA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Bos taurus 15554 R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 15554 R-BTA-2161549 https://reactome.org/PathwayBrowser/#/R-BTA-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Bos taurus 15554 R-BTA-2161613 https://reactome.org/PathwayBrowser/#/R-BTA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Bos taurus 15554 R-BTA-2161620 https://reactome.org/PathwayBrowser/#/R-BTA-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Bos taurus 15554 R-BTA-2161660 https://reactome.org/PathwayBrowser/#/R-BTA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Bos taurus 15554 R-BTA-2161701 https://reactome.org/PathwayBrowser/#/R-BTA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Bos taurus 15554 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 15554 R-BTA-265295 https://reactome.org/PathwayBrowser/#/R-BTA-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Bos taurus 15554 R-BTA-76496 https://reactome.org/PathwayBrowser/#/R-BTA-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Bos taurus 15554 R-BTA-76500 https://reactome.org/PathwayBrowser/#/R-BTA-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Bos taurus 15554 R-CEL-2161549 https://reactome.org/PathwayBrowser/#/R-CEL-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Caenorhabditis elegans 15554 R-CEL-2161701 https://reactome.org/PathwayBrowser/#/R-CEL-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Caenorhabditis elegans 15554 R-CEL-265295 https://reactome.org/PathwayBrowser/#/R-CEL-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Caenorhabditis elegans 15554 R-CFA-140359 https://reactome.org/PathwayBrowser/#/R-CFA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Canis familiaris 15554 R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 15554 R-CFA-2161613 https://reactome.org/PathwayBrowser/#/R-CFA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Canis familiaris 15554 R-CFA-2161620 https://reactome.org/PathwayBrowser/#/R-CFA-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Canis familiaris 15554 R-CFA-2161660 https://reactome.org/PathwayBrowser/#/R-CFA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Canis familiaris 15554 R-CFA-2161701 https://reactome.org/PathwayBrowser/#/R-CFA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Canis familiaris 15554 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 15554 R-CFA-265295 https://reactome.org/PathwayBrowser/#/R-CFA-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Canis familiaris 15554 R-CFA-76496 https://reactome.org/PathwayBrowser/#/R-CFA-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Canis familiaris 15554 R-CFA-76500 https://reactome.org/PathwayBrowser/#/R-CFA-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Canis familiaris 15554 R-DDI-2161549 https://reactome.org/PathwayBrowser/#/R-DDI-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Dictyostelium discoideum 15554 R-DDI-2161701 https://reactome.org/PathwayBrowser/#/R-DDI-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Dictyostelium discoideum 15554 R-DDI-265295 https://reactome.org/PathwayBrowser/#/R-DDI-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Dictyostelium discoideum 15554 R-DME-2161549 https://reactome.org/PathwayBrowser/#/R-DME-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Drosophila melanogaster 15554 R-DME-2161620 https://reactome.org/PathwayBrowser/#/R-DME-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Drosophila melanogaster 15554 R-DME-2161660 https://reactome.org/PathwayBrowser/#/R-DME-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Drosophila melanogaster 15554 R-DME-2161701 https://reactome.org/PathwayBrowser/#/R-DME-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Drosophila melanogaster 15554 R-DME-265295 https://reactome.org/PathwayBrowser/#/R-DME-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Drosophila melanogaster 15554 R-DRE-140359 https://reactome.org/PathwayBrowser/#/R-DRE-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Danio rerio 15554 R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 15554 R-DRE-2161620 https://reactome.org/PathwayBrowser/#/R-DRE-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Danio rerio 15554 R-DRE-2161660 https://reactome.org/PathwayBrowser/#/R-DRE-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Danio rerio 15554 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 15554 R-DRE-265295 https://reactome.org/PathwayBrowser/#/R-DRE-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Danio rerio 15554 R-DRE-76496 https://reactome.org/PathwayBrowser/#/R-DRE-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Danio rerio 15554 R-GGA-140359 https://reactome.org/PathwayBrowser/#/R-GGA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Gallus gallus 15554 R-GGA-2161613 https://reactome.org/PathwayBrowser/#/R-GGA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Gallus gallus 15554 R-GGA-2161620 https://reactome.org/PathwayBrowser/#/R-GGA-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Gallus gallus 15554 R-GGA-2161660 https://reactome.org/PathwayBrowser/#/R-GGA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Gallus gallus 15554 R-GGA-2161701 https://reactome.org/PathwayBrowser/#/R-GGA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Gallus gallus 15554 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 15554 R-GGA-265295 https://reactome.org/PathwayBrowser/#/R-GGA-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Gallus gallus 15554 R-GGA-76500 https://reactome.org/PathwayBrowser/#/R-GGA-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Gallus gallus 15554 R-HSA-140359 https://reactome.org/PathwayBrowser/#/R-HSA-140359 PGG2 is reduced to PGH2 by PTGS1 TAS Homo sapiens 15554 R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 15554 R-HSA-2161549 https://reactome.org/PathwayBrowser/#/R-HSA-2161549 PGH2 is reduced to PGF2a by AKR1C3 TAS Homo sapiens 15554 R-HSA-2161612 https://reactome.org/PathwayBrowser/#/R-HSA-2161612 PGH2 is reduced to PGF2a by FAM213B IEA Homo sapiens 15554 R-HSA-2161613 https://reactome.org/PathwayBrowser/#/R-HSA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 TAS Homo sapiens 15554 R-HSA-2161620 https://reactome.org/PathwayBrowser/#/R-HSA-2161620 PGH2 is isomerised to PGD2 by PTGDS TAS Homo sapiens 15554 R-HSA-2161660 https://reactome.org/PathwayBrowser/#/R-HSA-2161660 PGH2 is isomerised to PGE2 by PTGES TAS Homo sapiens 15554 R-HSA-2161701 https://reactome.org/PathwayBrowser/#/R-HSA-2161701 PGH2 is isomerised to PGD2 by HPGDS TAS Homo sapiens 15554 R-HSA-2299725 https://reactome.org/PathwayBrowser/#/R-HSA-2299725 PGH2 diffuses from the endoplasmic reticulum lumen to the cytosol TAS Homo sapiens 15554 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 15554 R-HSA-265295 https://reactome.org/PathwayBrowser/#/R-HSA-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 TAS Homo sapiens 15554 R-HSA-5603275 https://reactome.org/PathwayBrowser/#/R-HSA-5603275 Defective TBXAS1 does not isomerise PGH2 to TXA2 TAS Homo sapiens 15554 R-HSA-76496 https://reactome.org/PathwayBrowser/#/R-HSA-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 TAS Homo sapiens 15554 R-HSA-76500 https://reactome.org/PathwayBrowser/#/R-HSA-76500 TBXAS1 isomerises PGH2 to TXA2 TAS Homo sapiens 15554 R-MMU-140359 https://reactome.org/PathwayBrowser/#/R-MMU-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Mus musculus 15554 R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 15554 R-MMU-2161549 https://reactome.org/PathwayBrowser/#/R-MMU-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Mus musculus 15554 R-MMU-2161613 https://reactome.org/PathwayBrowser/#/R-MMU-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Mus musculus 15554 R-MMU-2161620 https://reactome.org/PathwayBrowser/#/R-MMU-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Mus musculus 15554 R-MMU-2161660 https://reactome.org/PathwayBrowser/#/R-MMU-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Mus musculus 15554 R-MMU-2161701 https://reactome.org/PathwayBrowser/#/R-MMU-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Mus musculus 15554 R-MMU-2161718 https://reactome.org/PathwayBrowser/#/R-MMU-2161718 PGH2 is reduced to PGF2a by Fam213b TAS Mus musculus 15554 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 15554 R-MMU-265295 https://reactome.org/PathwayBrowser/#/R-MMU-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Mus musculus 15554 R-MMU-76496 https://reactome.org/PathwayBrowser/#/R-MMU-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Mus musculus 15554 R-MMU-76500 https://reactome.org/PathwayBrowser/#/R-MMU-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Mus musculus 15554 R-PFA-2161701 https://reactome.org/PathwayBrowser/#/R-PFA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Plasmodium falciparum 15554 R-PFA-265295 https://reactome.org/PathwayBrowser/#/R-PFA-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Plasmodium falciparum 15554 R-RNO-140359 https://reactome.org/PathwayBrowser/#/R-RNO-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Rattus norvegicus 15554 R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 15554 R-RNO-2161549 https://reactome.org/PathwayBrowser/#/R-RNO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Rattus norvegicus 15554 R-RNO-2161613 https://reactome.org/PathwayBrowser/#/R-RNO-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Rattus norvegicus 15554 R-RNO-2161620 https://reactome.org/PathwayBrowser/#/R-RNO-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Rattus norvegicus 15554 R-RNO-2161660 https://reactome.org/PathwayBrowser/#/R-RNO-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Rattus norvegicus 15554 R-RNO-2161701 https://reactome.org/PathwayBrowser/#/R-RNO-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Rattus norvegicus 15554 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 15554 R-RNO-265295 https://reactome.org/PathwayBrowser/#/R-RNO-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Rattus norvegicus 15554 R-RNO-76496 https://reactome.org/PathwayBrowser/#/R-RNO-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Rattus norvegicus 15554 R-RNO-76500 https://reactome.org/PathwayBrowser/#/R-RNO-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Rattus norvegicus 15554 R-SCE-2161549 https://reactome.org/PathwayBrowser/#/R-SCE-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Saccharomyces cerevisiae 15554 R-SCE-265295 https://reactome.org/PathwayBrowser/#/R-SCE-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Saccharomyces cerevisiae 15554 R-SPO-2161549 https://reactome.org/PathwayBrowser/#/R-SPO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Schizosaccharomyces pombe 15554 R-SPO-265295 https://reactome.org/PathwayBrowser/#/R-SPO-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Schizosaccharomyces pombe 15554 R-SSC-140359 https://reactome.org/PathwayBrowser/#/R-SSC-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Sus scrofa 15554 R-SSC-211919 https://reactome.org/PathwayBrowser/#/R-SSC-211919 CYP4F8 19-hydroxylates PGH2 IEA Sus scrofa 15554 R-SSC-2161549 https://reactome.org/PathwayBrowser/#/R-SSC-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Sus scrofa 15554 R-SSC-2161613 https://reactome.org/PathwayBrowser/#/R-SSC-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Sus scrofa 15554 R-SSC-2161620 https://reactome.org/PathwayBrowser/#/R-SSC-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Sus scrofa 15554 R-SSC-2161660 https://reactome.org/PathwayBrowser/#/R-SSC-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Sus scrofa 15554 R-SSC-2161701 https://reactome.org/PathwayBrowser/#/R-SSC-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Sus scrofa 15554 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 15554 R-SSC-265295 https://reactome.org/PathwayBrowser/#/R-SSC-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Sus scrofa 15554 R-SSC-76496 https://reactome.org/PathwayBrowser/#/R-SSC-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Sus scrofa 15554 R-SSC-76500 https://reactome.org/PathwayBrowser/#/R-SSC-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Sus scrofa 15554 R-XTR-140359 https://reactome.org/PathwayBrowser/#/R-XTR-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Xenopus tropicalis 15554 R-XTR-211919 https://reactome.org/PathwayBrowser/#/R-XTR-211919 CYP4F8 19-hydroxylates PGH2 IEA Xenopus tropicalis 15554 R-XTR-2161549 https://reactome.org/PathwayBrowser/#/R-XTR-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Xenopus tropicalis 15554 R-XTR-2161620 https://reactome.org/PathwayBrowser/#/R-XTR-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Xenopus tropicalis 15554 R-XTR-2161660 https://reactome.org/PathwayBrowser/#/R-XTR-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Xenopus tropicalis 15554 R-XTR-2161701 https://reactome.org/PathwayBrowser/#/R-XTR-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Xenopus tropicalis 15554 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 15554 R-XTR-265295 https://reactome.org/PathwayBrowser/#/R-XTR-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Xenopus tropicalis 15554 R-XTR-76496 https://reactome.org/PathwayBrowser/#/R-XTR-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Xenopus tropicalis 15555 R-BTA-2161614 https://reactome.org/PathwayBrowser/#/R-BTA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Bos taurus 15555 R-BTA-2161620 https://reactome.org/PathwayBrowser/#/R-BTA-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Bos taurus 15555 R-BTA-2161701 https://reactome.org/PathwayBrowser/#/R-BTA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Bos taurus 15555 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 15555 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 15555 R-BTA-391934 https://reactome.org/PathwayBrowser/#/R-BTA-391934 DP2 receptor can bind PGD2 IEA Bos taurus 15555 R-BTA-391935 https://reactome.org/PathwayBrowser/#/R-BTA-391935 DP1 receptor can bind PGD2 IEA Bos taurus 15555 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 15555 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 15555 R-BTA-879528 https://reactome.org/PathwayBrowser/#/R-BTA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Bos taurus 15555 R-CEL-2161614 https://reactome.org/PathwayBrowser/#/R-CEL-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Caenorhabditis elegans 15555 R-CEL-2161701 https://reactome.org/PathwayBrowser/#/R-CEL-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Caenorhabditis elegans 15555 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 15555 R-CEL-391934 https://reactome.org/PathwayBrowser/#/R-CEL-391934 DP2 receptor can bind PGD2 IEA Caenorhabditis elegans 15555 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 15555 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 15555 R-CEL-879528 https://reactome.org/PathwayBrowser/#/R-CEL-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Caenorhabditis elegans 15555 R-CFA-2161620 https://reactome.org/PathwayBrowser/#/R-CFA-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Canis familiaris 15555 R-CFA-2161701 https://reactome.org/PathwayBrowser/#/R-CFA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Canis familiaris 15555 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 15555 R-CFA-391934 https://reactome.org/PathwayBrowser/#/R-CFA-391934 DP2 receptor can bind PGD2 IEA Canis familiaris 15555 R-CFA-391935 https://reactome.org/PathwayBrowser/#/R-CFA-391935 DP1 receptor can bind PGD2 IEA Canis familiaris 15555 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 15555 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 15555 R-CFA-879528 https://reactome.org/PathwayBrowser/#/R-CFA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Canis familiaris 15555 R-DDI-2161614 https://reactome.org/PathwayBrowser/#/R-DDI-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Dictyostelium discoideum 15555 R-DDI-2161701 https://reactome.org/PathwayBrowser/#/R-DDI-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Dictyostelium discoideum 15555 R-DME-2161614 https://reactome.org/PathwayBrowser/#/R-DME-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Drosophila melanogaster 15555 R-DME-2161620 https://reactome.org/PathwayBrowser/#/R-DME-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Drosophila melanogaster 15555 R-DME-2161701 https://reactome.org/PathwayBrowser/#/R-DME-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Drosophila melanogaster 15555 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 15555 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 15555 R-DME-391934 https://reactome.org/PathwayBrowser/#/R-DME-391934 DP2 receptor can bind PGD2 IEA Drosophila melanogaster 15555 R-DME-391935 https://reactome.org/PathwayBrowser/#/R-DME-391935 DP1 receptor can bind PGD2 IEA Drosophila melanogaster 15555 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 15555 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 15555 R-DME-879528 https://reactome.org/PathwayBrowser/#/R-DME-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Drosophila melanogaster 15555 R-DRE-2161620 https://reactome.org/PathwayBrowser/#/R-DRE-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Danio rerio 15555 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 15555 R-DRE-391934 https://reactome.org/PathwayBrowser/#/R-DRE-391934 DP2 receptor can bind PGD2 IEA Danio rerio 15555 R-GGA-2161620 https://reactome.org/PathwayBrowser/#/R-GGA-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Gallus gallus 15555 R-GGA-2161701 https://reactome.org/PathwayBrowser/#/R-GGA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Gallus gallus 15555 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 15555 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 15555 R-GGA-391934 https://reactome.org/PathwayBrowser/#/R-GGA-391934 DP2 receptor can bind PGD2 IEA Gallus gallus 15555 R-GGA-391935 https://reactome.org/PathwayBrowser/#/R-GGA-391935 DP1 receptor can bind PGD2 IEA Gallus gallus 15555 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 15555 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 15555 R-GGA-879528 https://reactome.org/PathwayBrowser/#/R-GGA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Gallus gallus 15555 R-HSA-2161614 https://reactome.org/PathwayBrowser/#/R-HSA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 TAS Homo sapiens 15555 R-HSA-2161620 https://reactome.org/PathwayBrowser/#/R-HSA-2161620 PGH2 is isomerised to PGD2 by PTGDS TAS Homo sapiens 15555 R-HSA-2161662 https://reactome.org/PathwayBrowser/#/R-HSA-2161662 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD IEA Homo sapiens 15555 R-HSA-2161673 https://reactome.org/PathwayBrowser/#/R-HSA-2161673 PGD2 is dehydrated to 15d-PGD2 TAS Homo sapiens 15555 R-HSA-2161701 https://reactome.org/PathwayBrowser/#/R-HSA-2161701 PGH2 is isomerised to PGD2 by HPGDS TAS Homo sapiens 15555 R-HSA-2161733 https://reactome.org/PathwayBrowser/#/R-HSA-2161733 PGD2 is dehydrated to PGJ2 TAS Homo sapiens 15555 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 15555 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 15555 R-HSA-391934 https://reactome.org/PathwayBrowser/#/R-HSA-391934 DP2 receptor can bind PGD2 TAS Homo sapiens 15555 R-HSA-391935 https://reactome.org/PathwayBrowser/#/R-HSA-391935 DP1 receptor can bind PGD2 TAS Homo sapiens 15555 R-HSA-5661188 https://reactome.org/PathwayBrowser/#/R-HSA-5661188 Defective SLCO2A1 does not transport PGT substrates from extracellular region to cytosol TAS Homo sapiens 15555 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 15555 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 15555 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 15555 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 15555 R-HSA-879528 https://reactome.org/PathwayBrowser/#/R-HSA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol TAS Homo sapiens 15555 R-HSA-9690404 https://reactome.org/PathwayBrowser/#/R-HSA-9690404 Expression of SOX9 in testis differentiation IEA Homo sapiens 15555 R-MMU-2161614 https://reactome.org/PathwayBrowser/#/R-MMU-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Mus musculus 15555 R-MMU-2161620 https://reactome.org/PathwayBrowser/#/R-MMU-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Mus musculus 15555 R-MMU-2161701 https://reactome.org/PathwayBrowser/#/R-MMU-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Mus musculus 15555 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 15555 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 15555 R-MMU-391934 https://reactome.org/PathwayBrowser/#/R-MMU-391934 DP2 receptor can bind PGD2 IEA Mus musculus 15555 R-MMU-391935 https://reactome.org/PathwayBrowser/#/R-MMU-391935 DP1 receptor can bind PGD2 IEA Mus musculus 15555 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 15555 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 15555 R-MMU-879528 https://reactome.org/PathwayBrowser/#/R-MMU-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Mus musculus 15555 R-OCU-2161568 https://reactome.org/PathwayBrowser/#/R-OCU-2161568 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD TAS Oryctolagus cuniculus 15555 R-PFA-2161701 https://reactome.org/PathwayBrowser/#/R-PFA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Plasmodium falciparum 15555 R-RNO-2161614 https://reactome.org/PathwayBrowser/#/R-RNO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Rattus norvegicus 15555 R-RNO-2161620 https://reactome.org/PathwayBrowser/#/R-RNO-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Rattus norvegicus 15555 R-RNO-2161701 https://reactome.org/PathwayBrowser/#/R-RNO-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Rattus norvegicus 15555 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 15555 R-RNO-391934 https://reactome.org/PathwayBrowser/#/R-RNO-391934 DP2 receptor can bind PGD2 IEA Rattus norvegicus 15555 R-RNO-391935 https://reactome.org/PathwayBrowser/#/R-RNO-391935 DP1 receptor can bind PGD2 IEA Rattus norvegicus 15555 R-RNO-879528 https://reactome.org/PathwayBrowser/#/R-RNO-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Rattus norvegicus 15555 R-SCE-2161614 https://reactome.org/PathwayBrowser/#/R-SCE-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Saccharomyces cerevisiae 15555 R-SPO-2161614 https://reactome.org/PathwayBrowser/#/R-SPO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Schizosaccharomyces pombe 15555 R-SSC-2161614 https://reactome.org/PathwayBrowser/#/R-SSC-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Sus scrofa 15555 R-SSC-2161620 https://reactome.org/PathwayBrowser/#/R-SSC-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Sus scrofa 15555 R-SSC-2161701 https://reactome.org/PathwayBrowser/#/R-SSC-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Sus scrofa 15555 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 15555 R-SSC-391935 https://reactome.org/PathwayBrowser/#/R-SSC-391935 DP1 receptor can bind PGD2 IEA Sus scrofa 15555 R-SSC-879528 https://reactome.org/PathwayBrowser/#/R-SSC-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Sus scrofa 15555 R-XTR-2161614 https://reactome.org/PathwayBrowser/#/R-XTR-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Xenopus tropicalis 15555 R-XTR-2161620 https://reactome.org/PathwayBrowser/#/R-XTR-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Xenopus tropicalis 15555 R-XTR-2161701 https://reactome.org/PathwayBrowser/#/R-XTR-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Xenopus tropicalis 15555 R-XTR-879528 https://reactome.org/PathwayBrowser/#/R-XTR-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Xenopus tropicalis 15557 R-HSA-2161662 https://reactome.org/PathwayBrowser/#/R-HSA-2161662 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD IEA Homo sapiens 15557 R-OCU-2161568 https://reactome.org/PathwayBrowser/#/R-OCU-2161568 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD TAS Oryctolagus cuniculus 15558 R-CFA-2161791 https://reactome.org/PathwayBrowser/#/R-CFA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Canis familiaris 15558 R-HSA-2161789 https://reactome.org/PathwayBrowser/#/R-HSA-2161789 15S-HETE is oxidised to 15-oxoETE by 15-HEDH TAS Homo sapiens 15558 R-HSA-2161791 https://reactome.org/PathwayBrowser/#/R-HSA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 TAS Homo sapiens 15558 R-MMU-2161791 https://reactome.org/PathwayBrowser/#/R-MMU-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Mus musculus 15558 R-RNO-2161791 https://reactome.org/PathwayBrowser/#/R-RNO-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Rattus norvegicus 15558 R-SSC-2161791 https://reactome.org/PathwayBrowser/#/R-SSC-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Sus scrofa 15559 R-HSA-2161789 https://reactome.org/PathwayBrowser/#/R-HSA-2161789 15S-HETE is oxidised to 15-oxoETE by 15-HEDH TAS Homo sapiens 15562 R-BTA-389540 https://reactome.org/PathwayBrowser/#/R-BTA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 15562 R-BTA-389550 https://reactome.org/PathwayBrowser/#/R-BTA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 15562 R-BTA-450984 https://reactome.org/PathwayBrowser/#/R-BTA-450984 IDH2 dimer decarboxylates isocitrate IEA Bos taurus 15562 R-BTA-5690911 https://reactome.org/PathwayBrowser/#/R-BTA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Bos taurus 15562 R-BTA-70967 https://reactome.org/PathwayBrowser/#/R-BTA-70967 IDH3 complex decarboxylates isocitrate IEA Bos taurus 15562 R-BTA-70971 https://reactome.org/PathwayBrowser/#/R-BTA-70971 ACO2 isomerizes citrate IEA Bos taurus 15562 R-CEL-389540 https://reactome.org/PathwayBrowser/#/R-CEL-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 15562 R-CEL-389550 https://reactome.org/PathwayBrowser/#/R-CEL-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 15562 R-CEL-450984 https://reactome.org/PathwayBrowser/#/R-CEL-450984 IDH2 dimer decarboxylates isocitrate IEA Caenorhabditis elegans 15562 R-CEL-5690911 https://reactome.org/PathwayBrowser/#/R-CEL-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Caenorhabditis elegans 15562 R-CEL-70967 https://reactome.org/PathwayBrowser/#/R-CEL-70967 IDH3 complex decarboxylates isocitrate IEA Caenorhabditis elegans 15562 R-CEL-70971 https://reactome.org/PathwayBrowser/#/R-CEL-70971 ACO2 isomerizes citrate IEA Caenorhabditis elegans 15562 R-CFA-389540 https://reactome.org/PathwayBrowser/#/R-CFA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 15562 R-CFA-389550 https://reactome.org/PathwayBrowser/#/R-CFA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 15562 R-CFA-450984 https://reactome.org/PathwayBrowser/#/R-CFA-450984 IDH2 dimer decarboxylates isocitrate IEA Canis familiaris 15562 R-CFA-5690911 https://reactome.org/PathwayBrowser/#/R-CFA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Canis familiaris 15562 R-CFA-70967 https://reactome.org/PathwayBrowser/#/R-CFA-70967 IDH3 complex decarboxylates isocitrate IEA Canis familiaris 15562 R-CFA-70971 https://reactome.org/PathwayBrowser/#/R-CFA-70971 ACO2 isomerizes citrate IEA Canis familiaris 15562 R-DDI-389540 https://reactome.org/PathwayBrowser/#/R-DDI-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 15562 R-DDI-389550 https://reactome.org/PathwayBrowser/#/R-DDI-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 15562 R-DDI-5690911 https://reactome.org/PathwayBrowser/#/R-DDI-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Dictyostelium discoideum 15562 R-DDI-70967 https://reactome.org/PathwayBrowser/#/R-DDI-70967 IDH3 complex decarboxylates isocitrate IEA Dictyostelium discoideum 15562 R-DDI-70971 https://reactome.org/PathwayBrowser/#/R-DDI-70971 ACO2 isomerizes citrate IEA Dictyostelium discoideum 15562 R-DME-389540 https://reactome.org/PathwayBrowser/#/R-DME-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 15562 R-DME-389550 https://reactome.org/PathwayBrowser/#/R-DME-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 15562 R-DME-5690911 https://reactome.org/PathwayBrowser/#/R-DME-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Drosophila melanogaster 15562 R-DME-70967 https://reactome.org/PathwayBrowser/#/R-DME-70967 IDH3 complex decarboxylates isocitrate IEA Drosophila melanogaster 15562 R-DME-70971 https://reactome.org/PathwayBrowser/#/R-DME-70971 ACO2 isomerizes citrate IEA Drosophila melanogaster 15562 R-DRE-389540 https://reactome.org/PathwayBrowser/#/R-DRE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 15562 R-DRE-389550 https://reactome.org/PathwayBrowser/#/R-DRE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 15562 R-DRE-450984 https://reactome.org/PathwayBrowser/#/R-DRE-450984 IDH2 dimer decarboxylates isocitrate IEA Danio rerio 15562 R-DRE-5690911 https://reactome.org/PathwayBrowser/#/R-DRE-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Danio rerio 15562 R-DRE-70971 https://reactome.org/PathwayBrowser/#/R-DRE-70971 ACO2 isomerizes citrate IEA Danio rerio 15562 R-GGA-373015 https://reactome.org/PathwayBrowser/#/R-GGA-373015 citrate <=> isocitrate TAS Gallus gallus 15562 R-GGA-373024 https://reactome.org/PathwayBrowser/#/R-GGA-373024 isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ IEA Gallus gallus 15562 R-GGA-373140 https://reactome.org/PathwayBrowser/#/R-GGA-373140 isocitrate <=> citrate TAS Gallus gallus 15562 R-GGA-389540 https://reactome.org/PathwayBrowser/#/R-GGA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 15562 R-GGA-389550 https://reactome.org/PathwayBrowser/#/R-GGA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 15562 R-GGA-450984 https://reactome.org/PathwayBrowser/#/R-GGA-450984 IDH2 dimer decarboxylates isocitrate IEA Gallus gallus 15562 R-GGA-5690911 https://reactome.org/PathwayBrowser/#/R-GGA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Gallus gallus 15562 R-GGA-70971 https://reactome.org/PathwayBrowser/#/R-GGA-70971 ACO2 isomerizes citrate IEA Gallus gallus 15562 R-HSA-389540 https://reactome.org/PathwayBrowser/#/R-HSA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 15562 R-HSA-389550 https://reactome.org/PathwayBrowser/#/R-HSA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 15562 R-HSA-390347 https://reactome.org/PathwayBrowser/#/R-HSA-390347 Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane TAS Homo sapiens 15562 R-HSA-450984 https://reactome.org/PathwayBrowser/#/R-HSA-450984 IDH2 dimer decarboxylates isocitrate TAS Homo sapiens 15562 R-HSA-5690911 https://reactome.org/PathwayBrowser/#/R-HSA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT TAS Homo sapiens 15562 R-HSA-70967 https://reactome.org/PathwayBrowser/#/R-HSA-70967 IDH3 complex decarboxylates isocitrate TAS Homo sapiens 15562 R-HSA-70971 https://reactome.org/PathwayBrowser/#/R-HSA-70971 ACO2 isomerizes citrate TAS Homo sapiens 15562 R-MMU-389540 https://reactome.org/PathwayBrowser/#/R-MMU-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 15562 R-MMU-389550 https://reactome.org/PathwayBrowser/#/R-MMU-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 15562 R-MMU-450984 https://reactome.org/PathwayBrowser/#/R-MMU-450984 IDH2 dimer decarboxylates isocitrate IEA Mus musculus 15562 R-MMU-5690911 https://reactome.org/PathwayBrowser/#/R-MMU-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Mus musculus 15562 R-MMU-70967 https://reactome.org/PathwayBrowser/#/R-MMU-70967 IDH3 complex decarboxylates isocitrate IEA Mus musculus 15562 R-MMU-70971 https://reactome.org/PathwayBrowser/#/R-MMU-70971 ACO2 isomerizes citrate IEA Mus musculus 15562 R-PFA-450984 https://reactome.org/PathwayBrowser/#/R-PFA-450984 IDH2 dimer decarboxylates isocitrate IEA Plasmodium falciparum 15562 R-PFA-5690911 https://reactome.org/PathwayBrowser/#/R-PFA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Plasmodium falciparum 15562 R-RNO-389540 https://reactome.org/PathwayBrowser/#/R-RNO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 15562 R-RNO-389550 https://reactome.org/PathwayBrowser/#/R-RNO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 15562 R-RNO-450984 https://reactome.org/PathwayBrowser/#/R-RNO-450984 IDH2 dimer decarboxylates isocitrate IEA Rattus norvegicus 15562 R-RNO-5690911 https://reactome.org/PathwayBrowser/#/R-RNO-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Rattus norvegicus 15562 R-RNO-70967 https://reactome.org/PathwayBrowser/#/R-RNO-70967 IDH3 complex decarboxylates isocitrate IEA Rattus norvegicus 15562 R-RNO-70971 https://reactome.org/PathwayBrowser/#/R-RNO-70971 ACO2 isomerizes citrate IEA Rattus norvegicus 15562 R-SCE-389540 https://reactome.org/PathwayBrowser/#/R-SCE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 15562 R-SCE-389550 https://reactome.org/PathwayBrowser/#/R-SCE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 15562 R-SCE-70967 https://reactome.org/PathwayBrowser/#/R-SCE-70967 IDH3 complex decarboxylates isocitrate IEA Saccharomyces cerevisiae 15562 R-SCE-70971 https://reactome.org/PathwayBrowser/#/R-SCE-70971 ACO2 isomerizes citrate IEA Saccharomyces cerevisiae 15562 R-SPO-389540 https://reactome.org/PathwayBrowser/#/R-SPO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 15562 R-SPO-389550 https://reactome.org/PathwayBrowser/#/R-SPO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 15562 R-SPO-70967 https://reactome.org/PathwayBrowser/#/R-SPO-70967 IDH3 complex decarboxylates isocitrate IEA Schizosaccharomyces pombe 15562 R-SPO-70971 https://reactome.org/PathwayBrowser/#/R-SPO-70971 ACO2 isomerizes citrate IEA Schizosaccharomyces pombe 15562 R-SSC-389540 https://reactome.org/PathwayBrowser/#/R-SSC-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 15562 R-SSC-389550 https://reactome.org/PathwayBrowser/#/R-SSC-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 15562 R-SSC-450984 https://reactome.org/PathwayBrowser/#/R-SSC-450984 IDH2 dimer decarboxylates isocitrate IEA Sus scrofa 15562 R-SSC-5690911 https://reactome.org/PathwayBrowser/#/R-SSC-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Sus scrofa 15562 R-SSC-70967 https://reactome.org/PathwayBrowser/#/R-SSC-70967 IDH3 complex decarboxylates isocitrate IEA Sus scrofa 15562 R-SSC-70971 https://reactome.org/PathwayBrowser/#/R-SSC-70971 ACO2 isomerizes citrate IEA Sus scrofa 15562 R-XTR-389540 https://reactome.org/PathwayBrowser/#/R-XTR-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 15562 R-XTR-389550 https://reactome.org/PathwayBrowser/#/R-XTR-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 15562 R-XTR-450984 https://reactome.org/PathwayBrowser/#/R-XTR-450984 IDH2 dimer decarboxylates isocitrate IEA Xenopus tropicalis 15562 R-XTR-5690911 https://reactome.org/PathwayBrowser/#/R-XTR-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Xenopus tropicalis 15562 R-XTR-70971 https://reactome.org/PathwayBrowser/#/R-XTR-70971 ACO2 isomerizes citrate IEA Xenopus tropicalis 15570 R-BTA-376200 https://reactome.org/PathwayBrowser/#/R-BTA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Bos taurus 15570 R-CFA-376200 https://reactome.org/PathwayBrowser/#/R-CFA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Canis familiaris 15570 R-DME-376200 https://reactome.org/PathwayBrowser/#/R-DME-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Drosophila melanogaster 15570 R-HSA-376200 https://reactome.org/PathwayBrowser/#/R-HSA-376200 SLC7A10-mediated uptake of small neutral amino acids TAS Homo sapiens 15570 R-MMU-376200 https://reactome.org/PathwayBrowser/#/R-MMU-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Mus musculus 15570 R-RNO-376200 https://reactome.org/PathwayBrowser/#/R-RNO-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Rattus norvegicus 15570 R-SSC-376200 https://reactome.org/PathwayBrowser/#/R-SSC-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Sus scrofa 15570 R-XTR-376200 https://reactome.org/PathwayBrowser/#/R-XTR-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Xenopus tropicalis 15589 R-BTA-1614546 https://reactome.org/PathwayBrowser/#/R-BTA-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Bos taurus 15589 R-BTA-198440 https://reactome.org/PathwayBrowser/#/R-BTA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Bos taurus 15589 R-BTA-372843 https://reactome.org/PathwayBrowser/#/R-BTA-372843 SLC25A10 mediates exchange of malate and phosphate IEA Bos taurus 15589 R-BTA-376851 https://reactome.org/PathwayBrowser/#/R-BTA-376851 SLC25A11 exchanges 2-OG and MAL IEA Bos taurus 15589 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 15589 R-BTA-70979 https://reactome.org/PathwayBrowser/#/R-BTA-70979 MDH2 dimer dehydrogenates MAL IEA Bos taurus 15589 R-BTA-70982 https://reactome.org/PathwayBrowser/#/R-BTA-70982 FH tetramer hydrates fumarate to L-malate IEA Bos taurus 15589 R-BTA-75849 https://reactome.org/PathwayBrowser/#/R-BTA-75849 SLC25A1 exchanges CIT and MAL IEA Bos taurus 15589 R-BTA-9012036 https://reactome.org/PathwayBrowser/#/R-BTA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Bos taurus 15589 R-BTA-9012268 https://reactome.org/PathwayBrowser/#/R-BTA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Bos taurus 15589 R-BTA-9012349 https://reactome.org/PathwayBrowser/#/R-BTA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Bos taurus 15589 R-BTA-9856871 https://reactome.org/PathwayBrowser/#/R-BTA-9856871 MDH1 reduces OA IEA Bos taurus 15589 R-CEL-1614546 https://reactome.org/PathwayBrowser/#/R-CEL-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Caenorhabditis elegans 15589 R-CEL-198440 https://reactome.org/PathwayBrowser/#/R-CEL-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Caenorhabditis elegans 15589 R-CEL-372843 https://reactome.org/PathwayBrowser/#/R-CEL-372843 SLC25A10 mediates exchange of malate and phosphate IEA Caenorhabditis elegans 15589 R-CEL-376851 https://reactome.org/PathwayBrowser/#/R-CEL-376851 SLC25A11 exchanges 2-OG and MAL IEA Caenorhabditis elegans 15589 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 15589 R-CEL-70979 https://reactome.org/PathwayBrowser/#/R-CEL-70979 MDH2 dimer dehydrogenates MAL IEA Caenorhabditis elegans 15589 R-CEL-70982 https://reactome.org/PathwayBrowser/#/R-CEL-70982 FH tetramer hydrates fumarate to L-malate IEA Caenorhabditis elegans 15589 R-CEL-75849 https://reactome.org/PathwayBrowser/#/R-CEL-75849 SLC25A1 exchanges CIT and MAL IEA Caenorhabditis elegans 15589 R-CEL-9012036 https://reactome.org/PathwayBrowser/#/R-CEL-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 15589 R-CEL-9012268 https://reactome.org/PathwayBrowser/#/R-CEL-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 15589 R-CEL-9012349 https://reactome.org/PathwayBrowser/#/R-CEL-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 15589 R-CEL-9856871 https://reactome.org/PathwayBrowser/#/R-CEL-9856871 MDH1 reduces OA IEA Caenorhabditis elegans 15589 R-CFA-1614546 https://reactome.org/PathwayBrowser/#/R-CFA-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Canis familiaris 15589 R-CFA-198440 https://reactome.org/PathwayBrowser/#/R-CFA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Canis familiaris 15589 R-CFA-372843 https://reactome.org/PathwayBrowser/#/R-CFA-372843 SLC25A10 mediates exchange of malate and phosphate IEA Canis familiaris 15589 R-CFA-376851 https://reactome.org/PathwayBrowser/#/R-CFA-376851 SLC25A11 exchanges 2-OG and MAL IEA Canis familiaris 15589 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 15589 R-CFA-70979 https://reactome.org/PathwayBrowser/#/R-CFA-70979 MDH2 dimer dehydrogenates MAL IEA Canis familiaris 15589 R-CFA-70982 https://reactome.org/PathwayBrowser/#/R-CFA-70982 FH tetramer hydrates fumarate to L-malate IEA Canis familiaris 15589 R-CFA-75849 https://reactome.org/PathwayBrowser/#/R-CFA-75849 SLC25A1 exchanges CIT and MAL IEA Canis familiaris 15589 R-CFA-9012036 https://reactome.org/PathwayBrowser/#/R-CFA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Canis familiaris 15589 R-CFA-9012268 https://reactome.org/PathwayBrowser/#/R-CFA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Canis familiaris 15589 R-CFA-9012349 https://reactome.org/PathwayBrowser/#/R-CFA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Canis familiaris 15589 R-CFA-9856871 https://reactome.org/PathwayBrowser/#/R-CFA-9856871 MDH1 reduces OA IEA Canis familiaris 15589 R-DDI-1614546 https://reactome.org/PathwayBrowser/#/R-DDI-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Dictyostelium discoideum 15589 R-DDI-372843 https://reactome.org/PathwayBrowser/#/R-DDI-372843 SLC25A10 mediates exchange of malate and phosphate IEA Dictyostelium discoideum 15589 R-DDI-70982 https://reactome.org/PathwayBrowser/#/R-DDI-70982 FH tetramer hydrates fumarate to L-malate IEA Dictyostelium discoideum 15589 R-DDI-9856871 https://reactome.org/PathwayBrowser/#/R-DDI-9856871 MDH1 reduces OA IEA Dictyostelium discoideum 15589 R-DME-1614546 https://reactome.org/PathwayBrowser/#/R-DME-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Drosophila melanogaster 15589 R-DME-198440 https://reactome.org/PathwayBrowser/#/R-DME-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Drosophila melanogaster 15589 R-DME-372843 https://reactome.org/PathwayBrowser/#/R-DME-372843 SLC25A10 mediates exchange of malate and phosphate IEA Drosophila melanogaster 15589 R-DME-376851 https://reactome.org/PathwayBrowser/#/R-DME-376851 SLC25A11 exchanges 2-OG and MAL IEA Drosophila melanogaster 15589 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 15589 R-DME-70979 https://reactome.org/PathwayBrowser/#/R-DME-70979 MDH2 dimer dehydrogenates MAL IEA Drosophila melanogaster 15589 R-DME-70982 https://reactome.org/PathwayBrowser/#/R-DME-70982 FH tetramer hydrates fumarate to L-malate IEA Drosophila melanogaster 15589 R-DME-75849 https://reactome.org/PathwayBrowser/#/R-DME-75849 SLC25A1 exchanges CIT and MAL IEA Drosophila melanogaster 15589 R-DME-9012036 https://reactome.org/PathwayBrowser/#/R-DME-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 15589 R-DME-9012268 https://reactome.org/PathwayBrowser/#/R-DME-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 15589 R-DME-9012349 https://reactome.org/PathwayBrowser/#/R-DME-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 15589 R-DME-9856871 https://reactome.org/PathwayBrowser/#/R-DME-9856871 MDH1 reduces OA IEA Drosophila melanogaster 15589 R-DRE-1614546 https://reactome.org/PathwayBrowser/#/R-DRE-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Danio rerio 15589 R-DRE-198440 https://reactome.org/PathwayBrowser/#/R-DRE-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Danio rerio 15589 R-DRE-372843 https://reactome.org/PathwayBrowser/#/R-DRE-372843 SLC25A10 mediates exchange of malate and phosphate IEA Danio rerio 15589 R-DRE-376851 https://reactome.org/PathwayBrowser/#/R-DRE-376851 SLC25A11 exchanges 2-OG and MAL IEA Danio rerio 15589 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 15589 R-DRE-70979 https://reactome.org/PathwayBrowser/#/R-DRE-70979 MDH2 dimer dehydrogenates MAL IEA Danio rerio 15589 R-DRE-70982 https://reactome.org/PathwayBrowser/#/R-DRE-70982 FH tetramer hydrates fumarate to L-malate IEA Danio rerio 15589 R-DRE-75849 https://reactome.org/PathwayBrowser/#/R-DRE-75849 SLC25A1 exchanges CIT and MAL IEA Danio rerio 15589 R-DRE-9012036 https://reactome.org/PathwayBrowser/#/R-DRE-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Danio rerio 15589 R-DRE-9012268 https://reactome.org/PathwayBrowser/#/R-DRE-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Danio rerio 15589 R-DRE-9012349 https://reactome.org/PathwayBrowser/#/R-DRE-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Danio rerio 15589 R-DRE-9856871 https://reactome.org/PathwayBrowser/#/R-DRE-9856871 MDH1 reduces OA IEA Danio rerio 15589 R-GGA-1614546 https://reactome.org/PathwayBrowser/#/R-GGA-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Gallus gallus 15589 R-GGA-198440 https://reactome.org/PathwayBrowser/#/R-GGA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Gallus gallus 15589 R-GGA-372422 https://reactome.org/PathwayBrowser/#/R-GGA-372422 oxaloacetate + NADH + H+ <=> malate + NAD+ TAS Gallus gallus 15589 R-GGA-372843 https://reactome.org/PathwayBrowser/#/R-GGA-372843 SLC25A10 mediates exchange of malate and phosphate IEA Gallus gallus 15589 R-GGA-372852 https://reactome.org/PathwayBrowser/#/R-GGA-372852 malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix] IEA Gallus gallus 15589 R-GGA-372855 https://reactome.org/PathwayBrowser/#/R-GGA-372855 malate + NAD+ <=> oxaloacetate + NADH + H+ TAS Gallus gallus 15589 R-GGA-373047 https://reactome.org/PathwayBrowser/#/R-GGA-373047 malate + NAD+ <=> oxaloacetate + NADH + H+ IEA Gallus gallus 15589 R-GGA-373141 https://reactome.org/PathwayBrowser/#/R-GGA-373141 malate <=> fumarate + H2O TAS Gallus gallus 15589 R-GGA-373145 https://reactome.org/PathwayBrowser/#/R-GGA-373145 fumarate + H2O <=> malate IEA Gallus gallus 15589 R-GGA-376851 https://reactome.org/PathwayBrowser/#/R-GGA-376851 SLC25A11 exchanges 2-OG and MAL IEA Gallus gallus 15589 R-GGA-376887 https://reactome.org/PathwayBrowser/#/R-GGA-376887 2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix] IEA Gallus gallus 15589 R-GGA-70979 https://reactome.org/PathwayBrowser/#/R-GGA-70979 MDH2 dimer dehydrogenates MAL IEA Gallus gallus 15589 R-GGA-70982 https://reactome.org/PathwayBrowser/#/R-GGA-70982 FH tetramer hydrates fumarate to L-malate IEA Gallus gallus 15589 R-GGA-75849 https://reactome.org/PathwayBrowser/#/R-GGA-75849 SLC25A1 exchanges CIT and MAL IEA Gallus gallus 15589 R-GGA-9012036 https://reactome.org/PathwayBrowser/#/R-GGA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Gallus gallus 15589 R-GGA-9012349 https://reactome.org/PathwayBrowser/#/R-GGA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Gallus gallus 15589 R-GGA-9856871 https://reactome.org/PathwayBrowser/#/R-GGA-9856871 MDH1 reduces OA IEA Gallus gallus 15589 R-HSA-1614546 https://reactome.org/PathwayBrowser/#/R-HSA-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate TAS Homo sapiens 15589 R-HSA-198440 https://reactome.org/PathwayBrowser/#/R-HSA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane TAS Homo sapiens 15589 R-HSA-372843 https://reactome.org/PathwayBrowser/#/R-HSA-372843 SLC25A10 mediates exchange of malate and phosphate TAS Homo sapiens 15589 R-HSA-376851 https://reactome.org/PathwayBrowser/#/R-HSA-376851 SLC25A11 exchanges 2-OG and MAL TAS Homo sapiens 15589 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 15589 R-HSA-70979 https://reactome.org/PathwayBrowser/#/R-HSA-70979 MDH2 dimer dehydrogenates MAL TAS Homo sapiens 15589 R-HSA-70982 https://reactome.org/PathwayBrowser/#/R-HSA-70982 FH tetramer hydrates fumarate to L-malate TAS Homo sapiens 15589 R-HSA-75849 https://reactome.org/PathwayBrowser/#/R-HSA-75849 SLC25A1 exchanges CIT and MAL TAS Homo sapiens 15589 R-HSA-9012036 https://reactome.org/PathwayBrowser/#/R-HSA-9012036 ME1 tetramer decarboxylates MAL to PYR TAS Homo sapiens 15589 R-HSA-9012268 https://reactome.org/PathwayBrowser/#/R-HSA-9012268 ME2 tetramer decarboxylates MAL to PYR TAS Homo sapiens 15589 R-HSA-9012349 https://reactome.org/PathwayBrowser/#/R-HSA-9012349 ME3 tetramer decarboxylates MAL to PYR TAS Homo sapiens 15589 R-HSA-9856871 https://reactome.org/PathwayBrowser/#/R-HSA-9856871 MDH1 reduces OA TAS Homo sapiens 15589 R-MMU-1614546 https://reactome.org/PathwayBrowser/#/R-MMU-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Mus musculus 15589 R-MMU-198440 https://reactome.org/PathwayBrowser/#/R-MMU-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Mus musculus 15589 R-MMU-372843 https://reactome.org/PathwayBrowser/#/R-MMU-372843 SLC25A10 mediates exchange of malate and phosphate IEA Mus musculus 15589 R-MMU-376851 https://reactome.org/PathwayBrowser/#/R-MMU-376851 SLC25A11 exchanges 2-OG and MAL IEA Mus musculus 15589 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 15589 R-MMU-70979 https://reactome.org/PathwayBrowser/#/R-MMU-70979 MDH2 dimer dehydrogenates MAL IEA Mus musculus 15589 R-MMU-70982 https://reactome.org/PathwayBrowser/#/R-MMU-70982 FH tetramer hydrates fumarate to L-malate IEA Mus musculus 15589 R-MMU-75849 https://reactome.org/PathwayBrowser/#/R-MMU-75849 SLC25A1 exchanges CIT and MAL IEA Mus musculus 15589 R-MMU-9012036 https://reactome.org/PathwayBrowser/#/R-MMU-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Mus musculus 15589 R-MMU-9012268 https://reactome.org/PathwayBrowser/#/R-MMU-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Mus musculus 15589 R-MMU-9012349 https://reactome.org/PathwayBrowser/#/R-MMU-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Mus musculus 15589 R-MMU-9856871 https://reactome.org/PathwayBrowser/#/R-MMU-9856871 MDH1 reduces OA IEA Mus musculus 15589 R-PFA-198440 https://reactome.org/PathwayBrowser/#/R-PFA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Plasmodium falciparum 15589 R-PFA-376851 https://reactome.org/PathwayBrowser/#/R-PFA-376851 SLC25A11 exchanges 2-OG and MAL IEA Plasmodium falciparum 15589 R-PFA-70979 https://reactome.org/PathwayBrowser/#/R-PFA-70979 MDH2 dimer dehydrogenates MAL IEA Plasmodium falciparum 15589 R-RNO-1614546 https://reactome.org/PathwayBrowser/#/R-RNO-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Rattus norvegicus 15589 R-RNO-198440 https://reactome.org/PathwayBrowser/#/R-RNO-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Rattus norvegicus 15589 R-RNO-372843 https://reactome.org/PathwayBrowser/#/R-RNO-372843 SLC25A10 mediates exchange of malate and phosphate IEA Rattus norvegicus 15589 R-RNO-376851 https://reactome.org/PathwayBrowser/#/R-RNO-376851 SLC25A11 exchanges 2-OG and MAL IEA Rattus norvegicus 15589 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 15589 R-RNO-70979 https://reactome.org/PathwayBrowser/#/R-RNO-70979 MDH2 dimer dehydrogenates MAL IEA Rattus norvegicus 15589 R-RNO-70982 https://reactome.org/PathwayBrowser/#/R-RNO-70982 FH tetramer hydrates fumarate to L-malate IEA Rattus norvegicus 15589 R-RNO-75849 https://reactome.org/PathwayBrowser/#/R-RNO-75849 SLC25A1 exchanges CIT and MAL IEA Rattus norvegicus 15589 R-RNO-9012036 https://reactome.org/PathwayBrowser/#/R-RNO-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 15589 R-RNO-9012268 https://reactome.org/PathwayBrowser/#/R-RNO-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 15589 R-RNO-9012349 https://reactome.org/PathwayBrowser/#/R-RNO-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 15589 R-RNO-9856871 https://reactome.org/PathwayBrowser/#/R-RNO-9856871 MDH1 reduces OA IEA Rattus norvegicus 15589 R-SCE-1614546 https://reactome.org/PathwayBrowser/#/R-SCE-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Saccharomyces cerevisiae 15589 R-SCE-372843 https://reactome.org/PathwayBrowser/#/R-SCE-372843 SLC25A10 mediates exchange of malate and phosphate IEA Saccharomyces cerevisiae 15589 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 15589 R-SCE-70979 https://reactome.org/PathwayBrowser/#/R-SCE-70979 MDH2 dimer dehydrogenates MAL IEA Saccharomyces cerevisiae 15589 R-SCE-70982 https://reactome.org/PathwayBrowser/#/R-SCE-70982 FH tetramer hydrates fumarate to L-malate IEA Saccharomyces cerevisiae 15589 R-SCE-75849 https://reactome.org/PathwayBrowser/#/R-SCE-75849 SLC25A1 exchanges CIT and MAL IEA Saccharomyces cerevisiae 15589 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 15589 R-SPO-70979 https://reactome.org/PathwayBrowser/#/R-SPO-70979 MDH2 dimer dehydrogenates MAL IEA Schizosaccharomyces pombe 15589 R-SPO-70982 https://reactome.org/PathwayBrowser/#/R-SPO-70982 FH tetramer hydrates fumarate to L-malate IEA Schizosaccharomyces pombe 15589 R-SPO-75849 https://reactome.org/PathwayBrowser/#/R-SPO-75849 SLC25A1 exchanges CIT and MAL IEA Schizosaccharomyces pombe 15589 R-SSC-1614546 https://reactome.org/PathwayBrowser/#/R-SSC-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Sus scrofa 15589 R-SSC-198440 https://reactome.org/PathwayBrowser/#/R-SSC-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Sus scrofa 15589 R-SSC-372843 https://reactome.org/PathwayBrowser/#/R-SSC-372843 SLC25A10 mediates exchange of malate and phosphate IEA Sus scrofa 15589 R-SSC-376851 https://reactome.org/PathwayBrowser/#/R-SSC-376851 SLC25A11 exchanges 2-OG and MAL IEA Sus scrofa 15589 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 15589 R-SSC-70979 https://reactome.org/PathwayBrowser/#/R-SSC-70979 MDH2 dimer dehydrogenates MAL IEA Sus scrofa 15589 R-SSC-70982 https://reactome.org/PathwayBrowser/#/R-SSC-70982 FH tetramer hydrates fumarate to L-malate IEA Sus scrofa 15589 R-SSC-75849 https://reactome.org/PathwayBrowser/#/R-SSC-75849 SLC25A1 exchanges CIT and MAL IEA Sus scrofa 15589 R-SSC-9012036 https://reactome.org/PathwayBrowser/#/R-SSC-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Sus scrofa 15589 R-SSC-9012268 https://reactome.org/PathwayBrowser/#/R-SSC-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Sus scrofa 15589 R-SSC-9012349 https://reactome.org/PathwayBrowser/#/R-SSC-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Sus scrofa 15589 R-SSC-9856871 https://reactome.org/PathwayBrowser/#/R-SSC-9856871 MDH1 reduces OA IEA Sus scrofa 15589 R-XTR-198440 https://reactome.org/PathwayBrowser/#/R-XTR-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Xenopus tropicalis 15589 R-XTR-376851 https://reactome.org/PathwayBrowser/#/R-XTR-376851 SLC25A11 exchanges 2-OG and MAL IEA Xenopus tropicalis 15589 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 15589 R-XTR-70979 https://reactome.org/PathwayBrowser/#/R-XTR-70979 MDH2 dimer dehydrogenates MAL IEA Xenopus tropicalis 15589 R-XTR-75849 https://reactome.org/PathwayBrowser/#/R-XTR-75849 SLC25A1 exchanges CIT and MAL IEA Xenopus tropicalis 15589 R-XTR-9012268 https://reactome.org/PathwayBrowser/#/R-XTR-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 15589 R-XTR-9012349 https://reactome.org/PathwayBrowser/#/R-XTR-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 15589 R-XTR-9856871 https://reactome.org/PathwayBrowser/#/R-XTR-9856871 MDH1 reduces OA IEA Xenopus tropicalis 15621 R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus 15621 R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 15621 R-CFA-141202 https://reactome.org/PathwayBrowser/#/R-CFA-141202 MAOB:FAD oxidatively deaminates TYR IEA Canis familiaris 15621 R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 15621 R-DDI-141202 https://reactome.org/PathwayBrowser/#/R-DDI-141202 MAOB:FAD oxidatively deaminates TYR IEA Dictyostelium discoideum 15621 R-DRE-141202 https://reactome.org/PathwayBrowser/#/R-DRE-141202 MAOB:FAD oxidatively deaminates TYR IEA Danio rerio 15621 R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus 15621 R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 15621 R-HSA-141202 https://reactome.org/PathwayBrowser/#/R-HSA-141202 MAOB:FAD oxidatively deaminates TYR TAS Homo sapiens 15621 R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 15621 R-MMU-141202 https://reactome.org/PathwayBrowser/#/R-MMU-141202 MAOB:FAD oxidatively deaminates TYR IEA Mus musculus 15621 R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 15621 R-RNO-141202 https://reactome.org/PathwayBrowser/#/R-RNO-141202 MAOB:FAD oxidatively deaminates TYR IEA Rattus norvegicus 15621 R-SSC-141202 https://reactome.org/PathwayBrowser/#/R-SSC-141202 MAOB:FAD oxidatively deaminates TYR IEA Sus scrofa 15621 R-SSC-5696146 https://reactome.org/PathwayBrowser/#/R-SSC-5696146 AOC2 deaminates TYR IEA Sus scrofa 15621 R-XTR-141202 https://reactome.org/PathwayBrowser/#/R-XTR-141202 MAOB:FAD oxidatively deaminates TYR IEA Xenopus tropicalis 15626 R-BTA-2161964 https://reactome.org/PathwayBrowser/#/R-BTA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Bos taurus 15626 R-BTA-2161999 https://reactome.org/PathwayBrowser/#/R-BTA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Bos taurus 15626 R-CEL-2161999 https://reactome.org/PathwayBrowser/#/R-CEL-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Caenorhabditis elegans 15626 R-CFA-2161964 https://reactome.org/PathwayBrowser/#/R-CFA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Canis familiaris 15626 R-CFA-2161999 https://reactome.org/PathwayBrowser/#/R-CFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Canis familiaris 15626 R-DDI-2161964 https://reactome.org/PathwayBrowser/#/R-DDI-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Dictyostelium discoideum 15626 R-DRE-2161964 https://reactome.org/PathwayBrowser/#/R-DRE-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Danio rerio 15626 R-GGA-2161999 https://reactome.org/PathwayBrowser/#/R-GGA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Gallus gallus 15626 R-HSA-2161964 https://reactome.org/PathwayBrowser/#/R-HSA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 TAS Homo sapiens 15626 R-HSA-2161999 https://reactome.org/PathwayBrowser/#/R-HSA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 TAS Homo sapiens 15626 R-MMU-2161964 https://reactome.org/PathwayBrowser/#/R-MMU-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Mus musculus 15626 R-MMU-2161999 https://reactome.org/PathwayBrowser/#/R-MMU-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Mus musculus 15626 R-PFA-2161999 https://reactome.org/PathwayBrowser/#/R-PFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Plasmodium falciparum 15626 R-RNO-2161964 https://reactome.org/PathwayBrowser/#/R-RNO-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Rattus norvegicus 15626 R-RNO-2161999 https://reactome.org/PathwayBrowser/#/R-RNO-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Rattus norvegicus 15626 R-SSC-2161964 https://reactome.org/PathwayBrowser/#/R-SSC-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Sus scrofa 15626 R-SSC-2161999 https://reactome.org/PathwayBrowser/#/R-SSC-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Sus scrofa 15627 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15627 R-BTA-391939 https://reactome.org/PathwayBrowser/#/R-BTA-391939 TP receptor can bind thromboxane IEA Bos taurus 15627 R-BTA-428749 https://reactome.org/PathwayBrowser/#/R-BTA-428749 Activated TP receptor binds G-proten Gq IEA Bos taurus 15627 R-BTA-428750 https://reactome.org/PathwayBrowser/#/R-BTA-428750 Gq activation by TP receptor IEA Bos taurus 15627 R-BTA-428752 https://reactome.org/PathwayBrowser/#/R-BTA-428752 Dissociation of the TP:Gq complex IEA Bos taurus 15627 R-BTA-428909 https://reactome.org/PathwayBrowser/#/R-BTA-428909 Activated TP receptor binds G-protein G13 IEA Bos taurus 15627 R-BTA-428917 https://reactome.org/PathwayBrowser/#/R-BTA-428917 G13 activation by TP receptor IEA Bos taurus 15627 R-BTA-428918 https://reactome.org/PathwayBrowser/#/R-BTA-428918 Dissociation of the TP:G13 complex IEA Bos taurus 15627 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15627 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15627 R-BTA-751019 https://reactome.org/PathwayBrowser/#/R-BTA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Bos taurus 15627 R-BTA-751027 https://reactome.org/PathwayBrowser/#/R-BTA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Bos taurus 15627 R-BTA-751029 https://reactome.org/PathwayBrowser/#/R-BTA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Bos taurus 15627 R-BTA-76500 https://reactome.org/PathwayBrowser/#/R-BTA-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Bos taurus 15627 R-BTA-9674529 https://reactome.org/PathwayBrowser/#/R-BTA-9674529 AAMP binds to TBXA2R IEA Bos taurus 15627 R-CEL-428750 https://reactome.org/PathwayBrowser/#/R-CEL-428750 Gq activation by TP receptor IEA Caenorhabditis elegans 15627 R-CEL-428917 https://reactome.org/PathwayBrowser/#/R-CEL-428917 G13 activation by TP receptor IEA Caenorhabditis elegans 15627 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15627 R-CEL-751019 https://reactome.org/PathwayBrowser/#/R-CEL-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Caenorhabditis elegans 15627 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15627 R-CFA-391939 https://reactome.org/PathwayBrowser/#/R-CFA-391939 TP receptor can bind thromboxane IEA Canis familiaris 15627 R-CFA-428749 https://reactome.org/PathwayBrowser/#/R-CFA-428749 Activated TP receptor binds G-proten Gq IEA Canis familiaris 15627 R-CFA-428750 https://reactome.org/PathwayBrowser/#/R-CFA-428750 Gq activation by TP receptor IEA Canis familiaris 15627 R-CFA-428752 https://reactome.org/PathwayBrowser/#/R-CFA-428752 Dissociation of the TP:Gq complex IEA Canis familiaris 15627 R-CFA-428909 https://reactome.org/PathwayBrowser/#/R-CFA-428909 Activated TP receptor binds G-protein G13 IEA Canis familiaris 15627 R-CFA-428917 https://reactome.org/PathwayBrowser/#/R-CFA-428917 G13 activation by TP receptor IEA Canis familiaris 15627 R-CFA-428918 https://reactome.org/PathwayBrowser/#/R-CFA-428918 Dissociation of the TP:G13 complex IEA Canis familiaris 15627 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15627 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15627 R-CFA-751019 https://reactome.org/PathwayBrowser/#/R-CFA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Canis familiaris 15627 R-CFA-751027 https://reactome.org/PathwayBrowser/#/R-CFA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Canis familiaris 15627 R-CFA-751029 https://reactome.org/PathwayBrowser/#/R-CFA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Canis familiaris 15627 R-CFA-76500 https://reactome.org/PathwayBrowser/#/R-CFA-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Canis familiaris 15627 R-CFA-9674529 https://reactome.org/PathwayBrowser/#/R-CFA-9674529 AAMP binds to TBXA2R IEA Canis familiaris 15627 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 15627 R-DME-391939 https://reactome.org/PathwayBrowser/#/R-DME-391939 TP receptor can bind thromboxane IEA Drosophila melanogaster 15627 R-DME-428749 https://reactome.org/PathwayBrowser/#/R-DME-428749 Activated TP receptor binds G-proten Gq IEA Drosophila melanogaster 15627 R-DME-428750 https://reactome.org/PathwayBrowser/#/R-DME-428750 Gq activation by TP receptor IEA Drosophila melanogaster 15627 R-DME-428752 https://reactome.org/PathwayBrowser/#/R-DME-428752 Dissociation of the TP:Gq complex IEA Drosophila melanogaster 15627 R-DME-428909 https://reactome.org/PathwayBrowser/#/R-DME-428909 Activated TP receptor binds G-protein G13 IEA Drosophila melanogaster 15627 R-DME-428917 https://reactome.org/PathwayBrowser/#/R-DME-428917 G13 activation by TP receptor IEA Drosophila melanogaster 15627 R-DME-428918 https://reactome.org/PathwayBrowser/#/R-DME-428918 Dissociation of the TP:G13 complex IEA Drosophila melanogaster 15627 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 15627 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15627 R-DME-751019 https://reactome.org/PathwayBrowser/#/R-DME-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Drosophila melanogaster 15627 R-DME-751027 https://reactome.org/PathwayBrowser/#/R-DME-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Drosophila melanogaster 15627 R-DME-751029 https://reactome.org/PathwayBrowser/#/R-DME-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Drosophila melanogaster 15627 R-DME-9674529 https://reactome.org/PathwayBrowser/#/R-DME-9674529 AAMP binds to TBXA2R IEA Drosophila melanogaster 15627 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 15627 R-DRE-391939 https://reactome.org/PathwayBrowser/#/R-DRE-391939 TP receptor can bind thromboxane IEA Danio rerio 15627 R-DRE-428750 https://reactome.org/PathwayBrowser/#/R-DRE-428750 Gq activation by TP receptor IEA Danio rerio 15627 R-DRE-428917 https://reactome.org/PathwayBrowser/#/R-DRE-428917 G13 activation by TP receptor IEA Danio rerio 15627 R-DRE-751029 https://reactome.org/PathwayBrowser/#/R-DRE-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Danio rerio 15627 R-DRE-9674529 https://reactome.org/PathwayBrowser/#/R-DRE-9674529 AAMP binds to TBXA2R IEA Danio rerio 15627 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 15627 R-GGA-391939 https://reactome.org/PathwayBrowser/#/R-GGA-391939 TP receptor can bind thromboxane IEA Gallus gallus 15627 R-GGA-428749 https://reactome.org/PathwayBrowser/#/R-GGA-428749 Activated TP receptor binds G-proten Gq IEA Gallus gallus 15627 R-GGA-428750 https://reactome.org/PathwayBrowser/#/R-GGA-428750 Gq activation by TP receptor IEA Gallus gallus 15627 R-GGA-428752 https://reactome.org/PathwayBrowser/#/R-GGA-428752 Dissociation of the TP:Gq complex IEA Gallus gallus 15627 R-GGA-428909 https://reactome.org/PathwayBrowser/#/R-GGA-428909 Activated TP receptor binds G-protein G13 IEA Gallus gallus 15627 R-GGA-428917 https://reactome.org/PathwayBrowser/#/R-GGA-428917 G13 activation by TP receptor IEA Gallus gallus 15627 R-GGA-428918 https://reactome.org/PathwayBrowser/#/R-GGA-428918 Dissociation of the TP:G13 complex IEA Gallus gallus 15627 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 15627 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15627 R-GGA-751019 https://reactome.org/PathwayBrowser/#/R-GGA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Gallus gallus 15627 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus 15627 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus 15627 R-GGA-76500 https://reactome.org/PathwayBrowser/#/R-GGA-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Gallus gallus 15627 R-GGA-9674529 https://reactome.org/PathwayBrowser/#/R-GGA-9674529 AAMP binds to TBXA2R IEA Gallus gallus 15627 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15627 R-HSA-391939 https://reactome.org/PathwayBrowser/#/R-HSA-391939 TP receptor can bind thromboxane TAS Homo sapiens 15627 R-HSA-428749 https://reactome.org/PathwayBrowser/#/R-HSA-428749 Activated TP receptor binds G-proten Gq TAS Homo sapiens 15627 R-HSA-428750 https://reactome.org/PathwayBrowser/#/R-HSA-428750 Gq activation by TP receptor TAS Homo sapiens 15627 R-HSA-428752 https://reactome.org/PathwayBrowser/#/R-HSA-428752 Dissociation of the TP:Gq complex TAS Homo sapiens 15627 R-HSA-428909 https://reactome.org/PathwayBrowser/#/R-HSA-428909 Activated TP receptor binds G-protein G13 TAS Homo sapiens 15627 R-HSA-428917 https://reactome.org/PathwayBrowser/#/R-HSA-428917 G13 activation by TP receptor TAS Homo sapiens 15627 R-HSA-428918 https://reactome.org/PathwayBrowser/#/R-HSA-428918 Dissociation of the TP:G13 complex TAS Homo sapiens 15627 R-HSA-443894 https://reactome.org/PathwayBrowser/#/R-HSA-443894 TXA2 is hydrolysed to TXB2 TAS Homo sapiens 15627 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15627 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15627 R-HSA-751019 https://reactome.org/PathwayBrowser/#/R-HSA-751019 The Ligand:GPCR:G12/13 complex dissociates TAS Homo sapiens 15627 R-HSA-751027 https://reactome.org/PathwayBrowser/#/R-HSA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 TAS Homo sapiens 15627 R-HSA-751029 https://reactome.org/PathwayBrowser/#/R-HSA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 TAS Homo sapiens 15627 R-HSA-76500 https://reactome.org/PathwayBrowser/#/R-HSA-76500 TBXAS1 isomerises PGH2 to TXA2 TAS Homo sapiens 15627 R-HSA-9674529 https://reactome.org/PathwayBrowser/#/R-HSA-9674529 AAMP binds to TBXA2R TAS Homo sapiens 15627 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15627 R-MMU-391939 https://reactome.org/PathwayBrowser/#/R-MMU-391939 TP receptor can bind thromboxane IEA Mus musculus 15627 R-MMU-428749 https://reactome.org/PathwayBrowser/#/R-MMU-428749 Activated TP receptor binds G-proten Gq IEA Mus musculus 15627 R-MMU-428750 https://reactome.org/PathwayBrowser/#/R-MMU-428750 Gq activation by TP receptor IEA Mus musculus 15627 R-MMU-428752 https://reactome.org/PathwayBrowser/#/R-MMU-428752 Dissociation of the TP:Gq complex IEA Mus musculus 15627 R-MMU-428909 https://reactome.org/PathwayBrowser/#/R-MMU-428909 Activated TP receptor binds G-protein G13 IEA Mus musculus 15627 R-MMU-428917 https://reactome.org/PathwayBrowser/#/R-MMU-428917 G13 activation by TP receptor IEA Mus musculus 15627 R-MMU-428918 https://reactome.org/PathwayBrowser/#/R-MMU-428918 Dissociation of the TP:G13 complex IEA Mus musculus 15627 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15627 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15627 R-MMU-751019 https://reactome.org/PathwayBrowser/#/R-MMU-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Mus musculus 15627 R-MMU-751027 https://reactome.org/PathwayBrowser/#/R-MMU-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Mus musculus 15627 R-MMU-751029 https://reactome.org/PathwayBrowser/#/R-MMU-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Mus musculus 15627 R-MMU-76500 https://reactome.org/PathwayBrowser/#/R-MMU-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Mus musculus 15627 R-MMU-9674529 https://reactome.org/PathwayBrowser/#/R-MMU-9674529 AAMP binds to TBXA2R IEA Mus musculus 15627 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15627 R-RNO-391939 https://reactome.org/PathwayBrowser/#/R-RNO-391939 TP receptor can bind thromboxane IEA Rattus norvegicus 15627 R-RNO-428750 https://reactome.org/PathwayBrowser/#/R-RNO-428750 Gq activation by TP receptor IEA Rattus norvegicus 15627 R-RNO-428917 https://reactome.org/PathwayBrowser/#/R-RNO-428917 G13 activation by TP receptor IEA Rattus norvegicus 15627 R-RNO-751029 https://reactome.org/PathwayBrowser/#/R-RNO-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Rattus norvegicus 15627 R-RNO-76500 https://reactome.org/PathwayBrowser/#/R-RNO-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Rattus norvegicus 15627 R-RNO-9674529 https://reactome.org/PathwayBrowser/#/R-RNO-9674529 AAMP binds to TBXA2R IEA Rattus norvegicus 15627 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15627 R-SSC-391939 https://reactome.org/PathwayBrowser/#/R-SSC-391939 TP receptor can bind thromboxane IEA Sus scrofa 15627 R-SSC-428749 https://reactome.org/PathwayBrowser/#/R-SSC-428749 Activated TP receptor binds G-proten Gq IEA Sus scrofa 15627 R-SSC-428750 https://reactome.org/PathwayBrowser/#/R-SSC-428750 Gq activation by TP receptor IEA Sus scrofa 15627 R-SSC-428752 https://reactome.org/PathwayBrowser/#/R-SSC-428752 Dissociation of the TP:Gq complex IEA Sus scrofa 15627 R-SSC-428909 https://reactome.org/PathwayBrowser/#/R-SSC-428909 Activated TP receptor binds G-protein G13 IEA Sus scrofa 15627 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa 15627 R-SSC-428918 https://reactome.org/PathwayBrowser/#/R-SSC-428918 Dissociation of the TP:G13 complex IEA Sus scrofa 15627 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15627 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15627 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa 15627 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa 15627 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa 15627 R-SSC-76500 https://reactome.org/PathwayBrowser/#/R-SSC-76500 TBXAS1 isomerises PGH2 to TXA2 IEA Sus scrofa 15627 R-SSC-9674529 https://reactome.org/PathwayBrowser/#/R-SSC-9674529 AAMP binds to TBXA2R IEA Sus scrofa 15627 R-XTR-391939 https://reactome.org/PathwayBrowser/#/R-XTR-391939 TP receptor can bind thromboxane IEA Xenopus tropicalis 15627 R-XTR-428749 https://reactome.org/PathwayBrowser/#/R-XTR-428749 Activated TP receptor binds G-proten Gq IEA Xenopus tropicalis 15627 R-XTR-428750 https://reactome.org/PathwayBrowser/#/R-XTR-428750 Gq activation by TP receptor IEA Xenopus tropicalis 15627 R-XTR-428752 https://reactome.org/PathwayBrowser/#/R-XTR-428752 Dissociation of the TP:Gq complex IEA Xenopus tropicalis 15627 R-XTR-428909 https://reactome.org/PathwayBrowser/#/R-XTR-428909 Activated TP receptor binds G-protein G13 IEA Xenopus tropicalis 15627 R-XTR-428917 https://reactome.org/PathwayBrowser/#/R-XTR-428917 G13 activation by TP receptor IEA Xenopus tropicalis 15627 R-XTR-428918 https://reactome.org/PathwayBrowser/#/R-XTR-428918 Dissociation of the TP:G13 complex IEA Xenopus tropicalis 15627 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 15627 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15627 R-XTR-751019 https://reactome.org/PathwayBrowser/#/R-XTR-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Xenopus tropicalis 15627 R-XTR-751027 https://reactome.org/PathwayBrowser/#/R-XTR-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Xenopus tropicalis 15627 R-XTR-751029 https://reactome.org/PathwayBrowser/#/R-XTR-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Xenopus tropicalis 15627 R-XTR-9674529 https://reactome.org/PathwayBrowser/#/R-XTR-9674529 AAMP binds to TBXA2R IEA Xenopus tropicalis 15628 R-BTA-2161917 https://reactome.org/PathwayBrowser/#/R-BTA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Bos taurus 15628 R-BTA-2162002 https://reactome.org/PathwayBrowser/#/R-BTA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Bos taurus 15628 R-CFA-2161791 https://reactome.org/PathwayBrowser/#/R-CFA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Canis familiaris 15628 R-CFA-2161917 https://reactome.org/PathwayBrowser/#/R-CFA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Canis familiaris 15628 R-CFA-2162002 https://reactome.org/PathwayBrowser/#/R-CFA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Canis familiaris 15628 R-DDI-2161917 https://reactome.org/PathwayBrowser/#/R-DDI-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Dictyostelium discoideum 15628 R-DDI-2162002 https://reactome.org/PathwayBrowser/#/R-DDI-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Dictyostelium discoideum 15628 R-DRE-2162002 https://reactome.org/PathwayBrowser/#/R-DRE-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Danio rerio 15628 R-GGA-2161917 https://reactome.org/PathwayBrowser/#/R-GGA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Gallus gallus 15628 R-GGA-2162002 https://reactome.org/PathwayBrowser/#/R-GGA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Gallus gallus 15628 R-HSA-2161791 https://reactome.org/PathwayBrowser/#/R-HSA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 TAS Homo sapiens 15628 R-HSA-2161917 https://reactome.org/PathwayBrowser/#/R-HSA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 TAS Homo sapiens 15628 R-HSA-2162002 https://reactome.org/PathwayBrowser/#/R-HSA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B TAS Homo sapiens 15628 R-MMU-2161791 https://reactome.org/PathwayBrowser/#/R-MMU-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Mus musculus 15628 R-MMU-2161917 https://reactome.org/PathwayBrowser/#/R-MMU-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Mus musculus 15628 R-MMU-2162002 https://reactome.org/PathwayBrowser/#/R-MMU-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Mus musculus 15628 R-RNO-2161791 https://reactome.org/PathwayBrowser/#/R-RNO-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Rattus norvegicus 15628 R-RNO-2161917 https://reactome.org/PathwayBrowser/#/R-RNO-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Rattus norvegicus 15628 R-RNO-2162002 https://reactome.org/PathwayBrowser/#/R-RNO-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Rattus norvegicus 15628 R-SSC-2161791 https://reactome.org/PathwayBrowser/#/R-SSC-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Sus scrofa 15628 R-SSC-2161917 https://reactome.org/PathwayBrowser/#/R-SSC-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Sus scrofa 15628 R-SSC-2162002 https://reactome.org/PathwayBrowser/#/R-SSC-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Sus scrofa 15628 R-XTR-2161917 https://reactome.org/PathwayBrowser/#/R-XTR-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Xenopus tropicalis 15628 R-XTR-2162002 https://reactome.org/PathwayBrowser/#/R-XTR-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Xenopus tropicalis 15630 R-BTA-5602295 https://reactome.org/PathwayBrowser/#/R-BTA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Bos taurus 15630 R-CFA-5602295 https://reactome.org/PathwayBrowser/#/R-CFA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Canis familiaris 15630 R-DRE-5602295 https://reactome.org/PathwayBrowser/#/R-DRE-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Danio rerio 15630 R-HSA-2161949 https://reactome.org/PathwayBrowser/#/R-HSA-2161949 HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH TAS Homo sapiens 15630 R-HSA-5602272 https://reactome.org/PathwayBrowser/#/R-HSA-5602272 Defective CYP4F22 does not 20-hydroxylate TrXA3 TAS Homo sapiens 15630 R-HSA-5602295 https://reactome.org/PathwayBrowser/#/R-HSA-5602295 CYP4F22 20-hydroxylates TrXA3 TAS Homo sapiens 15630 R-MMU-5602295 https://reactome.org/PathwayBrowser/#/R-MMU-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Mus musculus 15630 R-SSC-5602295 https://reactome.org/PathwayBrowser/#/R-SSC-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Sus scrofa 15630 R-XTR-5602295 https://reactome.org/PathwayBrowser/#/R-XTR-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Xenopus tropicalis 15632 R-BTA-265296 https://reactome.org/PathwayBrowser/#/R-BTA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Bos taurus 15632 R-BTA-266051 https://reactome.org/PathwayBrowser/#/R-BTA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Bos taurus 15632 R-CFA-265296 https://reactome.org/PathwayBrowser/#/R-CFA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Canis familiaris 15632 R-CFA-266051 https://reactome.org/PathwayBrowser/#/R-CFA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Canis familiaris 15632 R-DDI-265296 https://reactome.org/PathwayBrowser/#/R-DDI-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Dictyostelium discoideum 15632 R-DDI-266051 https://reactome.org/PathwayBrowser/#/R-DDI-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Dictyostelium discoideum 15632 R-GGA-265296 https://reactome.org/PathwayBrowser/#/R-GGA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Gallus gallus 15632 R-GGA-266051 https://reactome.org/PathwayBrowser/#/R-GGA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Gallus gallus 15632 R-HSA-2161946 https://reactome.org/PathwayBrowser/#/R-HSA-2161946 5S-HpETE is reduced to 5S-HETE by GPX1/2/4 IEA Homo sapiens 15632 R-HSA-265296 https://reactome.org/PathwayBrowser/#/R-HSA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 TAS Homo sapiens 15632 R-HSA-266051 https://reactome.org/PathwayBrowser/#/R-HSA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 TAS Homo sapiens 15632 R-MMU-265296 https://reactome.org/PathwayBrowser/#/R-MMU-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Mus musculus 15632 R-MMU-266051 https://reactome.org/PathwayBrowser/#/R-MMU-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Mus musculus 15632 R-OCU-2161896 https://reactome.org/PathwayBrowser/#/R-OCU-2161896 5S-HpETE is reduced to 5S-HETE by GPX1 TAS Oryctolagus cuniculus 15632 R-RNO-265296 https://reactome.org/PathwayBrowser/#/R-RNO-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Rattus norvegicus 15632 R-RNO-266051 https://reactome.org/PathwayBrowser/#/R-RNO-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Rattus norvegicus 15632 R-SSC-265296 https://reactome.org/PathwayBrowser/#/R-SSC-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Sus scrofa 15632 R-SSC-266051 https://reactome.org/PathwayBrowser/#/R-SSC-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Sus scrofa 15632 R-XTR-265296 https://reactome.org/PathwayBrowser/#/R-XTR-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Xenopus tropicalis 15632 R-XTR-266051 https://reactome.org/PathwayBrowser/#/R-XTR-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Xenopus tropicalis 15635 R-BTA-200680 https://reactome.org/PathwayBrowser/#/R-BTA-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Bos taurus 15635 R-BTA-200682 https://reactome.org/PathwayBrowser/#/R-BTA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Bos taurus 15635 R-BTA-200720 https://reactome.org/PathwayBrowser/#/R-BTA-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Bos taurus 15635 R-BTA-5432520 https://reactome.org/PathwayBrowser/#/R-BTA-5432520 MTFMT formylates methionyl-tRNA TAS Bos taurus 15635 R-BTA-5693977 https://reactome.org/PathwayBrowser/#/R-BTA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Bos taurus 15635 R-BTA-5694137 https://reactome.org/PathwayBrowser/#/R-BTA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Bos taurus 15635 R-BTA-5696839 https://reactome.org/PathwayBrowser/#/R-BTA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Bos taurus 15635 R-BTA-6801456 https://reactome.org/PathwayBrowser/#/R-BTA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Bos taurus 15635 R-CEL-200680 https://reactome.org/PathwayBrowser/#/R-CEL-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Caenorhabditis elegans 15635 R-CEL-200682 https://reactome.org/PathwayBrowser/#/R-CEL-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Caenorhabditis elegans 15635 R-CEL-200720 https://reactome.org/PathwayBrowser/#/R-CEL-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Caenorhabditis elegans 15635 R-CEL-5693977 https://reactome.org/PathwayBrowser/#/R-CEL-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Caenorhabditis elegans 15635 R-CEL-5696839 https://reactome.org/PathwayBrowser/#/R-CEL-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Caenorhabditis elegans 15635 R-CEL-6801456 https://reactome.org/PathwayBrowser/#/R-CEL-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Caenorhabditis elegans 15635 R-CFA-200680 https://reactome.org/PathwayBrowser/#/R-CFA-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Canis familiaris 15635 R-CFA-200682 https://reactome.org/PathwayBrowser/#/R-CFA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Canis familiaris 15635 R-CFA-200720 https://reactome.org/PathwayBrowser/#/R-CFA-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Canis familiaris 15635 R-CFA-5693977 https://reactome.org/PathwayBrowser/#/R-CFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Canis familiaris 15635 R-CFA-5694137 https://reactome.org/PathwayBrowser/#/R-CFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Canis familiaris 15635 R-CFA-5696839 https://reactome.org/PathwayBrowser/#/R-CFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Canis familiaris 15635 R-CFA-6801456 https://reactome.org/PathwayBrowser/#/R-CFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Canis familiaris 15635 R-DDI-200680 https://reactome.org/PathwayBrowser/#/R-DDI-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Dictyostelium discoideum 15635 R-DDI-200682 https://reactome.org/PathwayBrowser/#/R-DDI-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Dictyostelium discoideum 15635 R-DDI-200720 https://reactome.org/PathwayBrowser/#/R-DDI-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Dictyostelium discoideum 15635 R-DDI-5693977 https://reactome.org/PathwayBrowser/#/R-DDI-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Dictyostelium discoideum 15635 R-DDI-5694137 https://reactome.org/PathwayBrowser/#/R-DDI-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Dictyostelium discoideum 15635 R-DDI-5696839 https://reactome.org/PathwayBrowser/#/R-DDI-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Dictyostelium discoideum 15635 R-DDI-6801456 https://reactome.org/PathwayBrowser/#/R-DDI-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Dictyostelium discoideum 15635 R-DME-200680 https://reactome.org/PathwayBrowser/#/R-DME-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Drosophila melanogaster 15635 R-DME-200682 https://reactome.org/PathwayBrowser/#/R-DME-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Drosophila melanogaster 15635 R-DME-200720 https://reactome.org/PathwayBrowser/#/R-DME-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Drosophila melanogaster 15635 R-DME-5693977 https://reactome.org/PathwayBrowser/#/R-DME-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Drosophila melanogaster 15635 R-DME-5696839 https://reactome.org/PathwayBrowser/#/R-DME-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Drosophila melanogaster 15635 R-DME-6801456 https://reactome.org/PathwayBrowser/#/R-DME-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Drosophila melanogaster 15635 R-DRE-200680 https://reactome.org/PathwayBrowser/#/R-DRE-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Danio rerio 15635 R-DRE-200682 https://reactome.org/PathwayBrowser/#/R-DRE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Danio rerio 15635 R-DRE-200720 https://reactome.org/PathwayBrowser/#/R-DRE-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Danio rerio 15635 R-DRE-5693977 https://reactome.org/PathwayBrowser/#/R-DRE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Danio rerio 15635 R-DRE-5694137 https://reactome.org/PathwayBrowser/#/R-DRE-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Danio rerio 15635 R-DRE-5696839 https://reactome.org/PathwayBrowser/#/R-DRE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Danio rerio 15635 R-DRE-6801456 https://reactome.org/PathwayBrowser/#/R-DRE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Danio rerio 15635 R-GGA-200680 https://reactome.org/PathwayBrowser/#/R-GGA-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Gallus gallus 15635 R-GGA-200682 https://reactome.org/PathwayBrowser/#/R-GGA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Gallus gallus 15635 R-GGA-200720 https://reactome.org/PathwayBrowser/#/R-GGA-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Gallus gallus 15635 R-GGA-5696839 https://reactome.org/PathwayBrowser/#/R-GGA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Gallus gallus 15635 R-GGA-6801456 https://reactome.org/PathwayBrowser/#/R-GGA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Gallus gallus 15635 R-HSA-200680 https://reactome.org/PathwayBrowser/#/R-HSA-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix TAS Homo sapiens 15635 R-HSA-200682 https://reactome.org/PathwayBrowser/#/R-HSA-200682 Mitochondrial FPGS-1 transforms THF to THFPG TAS Homo sapiens 15635 R-HSA-200720 https://reactome.org/PathwayBrowser/#/R-HSA-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol TAS Homo sapiens 15635 R-HSA-5389841 https://reactome.org/PathwayBrowser/#/R-HSA-5389841 MTFMT formylates methionyl-tRNA IEA Homo sapiens 15635 R-HSA-5693977 https://reactome.org/PathwayBrowser/#/R-HSA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF TAS Homo sapiens 15635 R-HSA-5694137 https://reactome.org/PathwayBrowser/#/R-HSA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser TAS Homo sapiens 15635 R-HSA-5696839 https://reactome.org/PathwayBrowser/#/R-HSA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF TAS Homo sapiens 15635 R-HSA-6801456 https://reactome.org/PathwayBrowser/#/R-HSA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF TAS Homo sapiens 15635 R-MMU-200680 https://reactome.org/PathwayBrowser/#/R-MMU-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Mus musculus 15635 R-MMU-200682 https://reactome.org/PathwayBrowser/#/R-MMU-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Mus musculus 15635 R-MMU-200720 https://reactome.org/PathwayBrowser/#/R-MMU-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Mus musculus 15635 R-MMU-5693977 https://reactome.org/PathwayBrowser/#/R-MMU-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Mus musculus 15635 R-MMU-5694137 https://reactome.org/PathwayBrowser/#/R-MMU-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Mus musculus 15635 R-MMU-5696839 https://reactome.org/PathwayBrowser/#/R-MMU-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Mus musculus 15635 R-MMU-6801456 https://reactome.org/PathwayBrowser/#/R-MMU-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Mus musculus 15635 R-PFA-200680 https://reactome.org/PathwayBrowser/#/R-PFA-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Plasmodium falciparum 15635 R-PFA-200720 https://reactome.org/PathwayBrowser/#/R-PFA-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Plasmodium falciparum 15635 R-PFA-5693977 https://reactome.org/PathwayBrowser/#/R-PFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Plasmodium falciparum 15635 R-PFA-5694137 https://reactome.org/PathwayBrowser/#/R-PFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Plasmodium falciparum 15635 R-PFA-5696839 https://reactome.org/PathwayBrowser/#/R-PFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Plasmodium falciparum 15635 R-PFA-6801456 https://reactome.org/PathwayBrowser/#/R-PFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Plasmodium falciparum 15635 R-RNO-200680 https://reactome.org/PathwayBrowser/#/R-RNO-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Rattus norvegicus 15635 R-RNO-200682 https://reactome.org/PathwayBrowser/#/R-RNO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Rattus norvegicus 15635 R-RNO-200720 https://reactome.org/PathwayBrowser/#/R-RNO-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Rattus norvegicus 15635 R-RNO-5693977 https://reactome.org/PathwayBrowser/#/R-RNO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Rattus norvegicus 15635 R-RNO-5694137 https://reactome.org/PathwayBrowser/#/R-RNO-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Rattus norvegicus 15635 R-RNO-5696839 https://reactome.org/PathwayBrowser/#/R-RNO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Rattus norvegicus 15635 R-RNO-6801456 https://reactome.org/PathwayBrowser/#/R-RNO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Rattus norvegicus 15635 R-SCE-200680 https://reactome.org/PathwayBrowser/#/R-SCE-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Saccharomyces cerevisiae 15635 R-SCE-200682 https://reactome.org/PathwayBrowser/#/R-SCE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Saccharomyces cerevisiae 15635 R-SCE-200720 https://reactome.org/PathwayBrowser/#/R-SCE-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Saccharomyces cerevisiae 15635 R-SCE-5693977 https://reactome.org/PathwayBrowser/#/R-SCE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Saccharomyces cerevisiae 15635 R-SCE-5696839 https://reactome.org/PathwayBrowser/#/R-SCE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Saccharomyces cerevisiae 15635 R-SCE-6801456 https://reactome.org/PathwayBrowser/#/R-SCE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Saccharomyces cerevisiae 15635 R-SPO-200680 https://reactome.org/PathwayBrowser/#/R-SPO-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Schizosaccharomyces pombe 15635 R-SPO-200682 https://reactome.org/PathwayBrowser/#/R-SPO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Schizosaccharomyces pombe 15635 R-SPO-200720 https://reactome.org/PathwayBrowser/#/R-SPO-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Schizosaccharomyces pombe 15635 R-SPO-5693977 https://reactome.org/PathwayBrowser/#/R-SPO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Schizosaccharomyces pombe 15635 R-SPO-5696839 https://reactome.org/PathwayBrowser/#/R-SPO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Schizosaccharomyces pombe 15635 R-SPO-6801456 https://reactome.org/PathwayBrowser/#/R-SPO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Schizosaccharomyces pombe 15635 R-SSC-200680 https://reactome.org/PathwayBrowser/#/R-SSC-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Sus scrofa 15635 R-SSC-200682 https://reactome.org/PathwayBrowser/#/R-SSC-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Sus scrofa 15635 R-SSC-200720 https://reactome.org/PathwayBrowser/#/R-SSC-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Sus scrofa 15635 R-SSC-5693977 https://reactome.org/PathwayBrowser/#/R-SSC-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Sus scrofa 15635 R-SSC-5694137 https://reactome.org/PathwayBrowser/#/R-SSC-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Sus scrofa 15635 R-SSC-5696839 https://reactome.org/PathwayBrowser/#/R-SSC-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Sus scrofa 15635 R-SSC-6801456 https://reactome.org/PathwayBrowser/#/R-SSC-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Sus scrofa 15635 R-XTR-200680 https://reactome.org/PathwayBrowser/#/R-XTR-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Xenopus tropicalis 15635 R-XTR-200682 https://reactome.org/PathwayBrowser/#/R-XTR-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Xenopus tropicalis 15635 R-XTR-200720 https://reactome.org/PathwayBrowser/#/R-XTR-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Xenopus tropicalis 15635 R-XTR-5693977 https://reactome.org/PathwayBrowser/#/R-XTR-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Xenopus tropicalis 15635 R-XTR-5694137 https://reactome.org/PathwayBrowser/#/R-XTR-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Xenopus tropicalis 15635 R-XTR-5696839 https://reactome.org/PathwayBrowser/#/R-XTR-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Xenopus tropicalis 15635 R-XTR-6801456 https://reactome.org/PathwayBrowser/#/R-XTR-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Xenopus tropicalis 156377 R-HSA-2067713 https://reactome.org/PathwayBrowser/#/R-HSA-2067713 GP369 inhibits activation of amplified FGFR2 signaling TAS Homo sapiens 15639 R-BTA-70920 https://reactome.org/PathwayBrowser/#/R-BTA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Bos taurus 15639 R-CFA-70920 https://reactome.org/PathwayBrowser/#/R-CFA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Canis familiaris 15639 R-DDI-70920 https://reactome.org/PathwayBrowser/#/R-DDI-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Dictyostelium discoideum 15639 R-GGA-70920 https://reactome.org/PathwayBrowser/#/R-GGA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Gallus gallus 15639 R-HSA-70920 https://reactome.org/PathwayBrowser/#/R-HSA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate TAS Homo sapiens 15639 R-MMU-70920 https://reactome.org/PathwayBrowser/#/R-MMU-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Mus musculus 15639 R-RNO-70920 https://reactome.org/PathwayBrowser/#/R-RNO-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Rattus norvegicus 15639 R-SSC-70920 https://reactome.org/PathwayBrowser/#/R-SSC-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Sus scrofa 15639 R-XTR-70920 https://reactome.org/PathwayBrowser/#/R-XTR-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Xenopus tropicalis 156439 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 156439 R-BTA-70800 https://reactome.org/PathwayBrowser/#/R-BTA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Bos taurus 156439 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 156439 R-CEL-70800 https://reactome.org/PathwayBrowser/#/R-CEL-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Caenorhabditis elegans 156439 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 156439 R-CFA-70800 https://reactome.org/PathwayBrowser/#/R-CFA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Canis familiaris 156439 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 156439 R-DDI-70800 https://reactome.org/PathwayBrowser/#/R-DDI-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Dictyostelium discoideum 156439 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 156439 R-DME-70800 https://reactome.org/PathwayBrowser/#/R-DME-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Drosophila melanogaster 156439 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 156439 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 156439 R-GGA-70800 https://reactome.org/PathwayBrowser/#/R-GGA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Gallus gallus 156439 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 156439 R-HSA-70800 https://reactome.org/PathwayBrowser/#/R-HSA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 TAS Homo sapiens 156439 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 156439 R-MMU-70800 https://reactome.org/PathwayBrowser/#/R-MMU-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Mus musculus 156439 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 156439 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 156439 R-RNO-70800 https://reactome.org/PathwayBrowser/#/R-RNO-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Rattus norvegicus 156439 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 156439 R-SSC-70800 https://reactome.org/PathwayBrowser/#/R-SSC-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Sus scrofa 156439 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 156439 R-XTR-70800 https://reactome.org/PathwayBrowser/#/R-XTR-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Xenopus tropicalis 15646 R-BTA-211873 https://reactome.org/PathwayBrowser/#/R-BTA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Bos taurus 15646 R-BTA-2161745 https://reactome.org/PathwayBrowser/#/R-BTA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Bos taurus 15646 R-CFA-211873 https://reactome.org/PathwayBrowser/#/R-CFA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Canis familiaris 15646 R-CFA-2161745 https://reactome.org/PathwayBrowser/#/R-CFA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15646 R-DRE-211873 https://reactome.org/PathwayBrowser/#/R-DRE-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Danio rerio 15646 R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 15646 R-DRE-2161745 https://reactome.org/PathwayBrowser/#/R-DRE-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Danio rerio 15646 R-HSA-211873 https://reactome.org/PathwayBrowser/#/R-HSA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 TAS Homo sapiens 15646 R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 15646 R-HSA-2161745 https://reactome.org/PathwayBrowser/#/R-HSA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15646 R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus 15646 R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 15646 R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus 15646 R-RNO-211873 https://reactome.org/PathwayBrowser/#/R-RNO-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Rattus norvegicus 15646 R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 15646 R-RNO-2161745 https://reactome.org/PathwayBrowser/#/R-RNO-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15646 R-SSC-211873 https://reactome.org/PathwayBrowser/#/R-SSC-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Sus scrofa 15646 R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa 15646 R-SSC-2161745 https://reactome.org/PathwayBrowser/#/R-SSC-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Sus scrofa 15646 R-XTR-211873 https://reactome.org/PathwayBrowser/#/R-XTR-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Xenopus tropicalis 15646 R-XTR-215526 https://reactome.org/PathwayBrowser/#/R-XTR-215526 CYP4F3 20-hydroxylates LTB4 IEA Xenopus tropicalis 15646 R-XTR-2161745 https://reactome.org/PathwayBrowser/#/R-XTR-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 15647 R-BTA-211873 https://reactome.org/PathwayBrowser/#/R-BTA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Bos taurus 15647 R-BTA-266072 https://reactome.org/PathwayBrowser/#/R-BTA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Bos taurus 15647 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15647 R-BTA-391941 https://reactome.org/PathwayBrowser/#/R-BTA-391941 BLT receptors can bind LTB4 IEA Bos taurus 15647 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15647 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15647 R-CEL-266072 https://reactome.org/PathwayBrowser/#/R-CEL-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Caenorhabditis elegans 15647 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 15647 R-CEL-391941 https://reactome.org/PathwayBrowser/#/R-CEL-391941 BLT receptors can bind LTB4 IEA Caenorhabditis elegans 15647 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 15647 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15647 R-CFA-211873 https://reactome.org/PathwayBrowser/#/R-CFA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Canis familiaris 15647 R-CFA-266072 https://reactome.org/PathwayBrowser/#/R-CFA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Canis familiaris 15647 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15647 R-CFA-391941 https://reactome.org/PathwayBrowser/#/R-CFA-391941 BLT receptors can bind LTB4 IEA Canis familiaris 15647 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15647 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15647 R-DDI-266072 https://reactome.org/PathwayBrowser/#/R-DDI-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Dictyostelium discoideum 15647 R-DME-266072 https://reactome.org/PathwayBrowser/#/R-DME-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Drosophila melanogaster 15647 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 15647 R-DME-391941 https://reactome.org/PathwayBrowser/#/R-DME-391941 BLT receptors can bind LTB4 IEA Drosophila melanogaster 15647 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 15647 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15647 R-DRE-211873 https://reactome.org/PathwayBrowser/#/R-DRE-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Danio rerio 15647 R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 15647 R-DRE-266072 https://reactome.org/PathwayBrowser/#/R-DRE-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Danio rerio 15647 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 15647 R-DRE-391941 https://reactome.org/PathwayBrowser/#/R-DRE-391941 BLT receptors can bind LTB4 IEA Danio rerio 15647 R-GGA-266072 https://reactome.org/PathwayBrowser/#/R-GGA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Gallus gallus 15647 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15647 R-HSA-211873 https://reactome.org/PathwayBrowser/#/R-HSA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 TAS Homo sapiens 15647 R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 15647 R-HSA-2161567 https://reactome.org/PathwayBrowser/#/R-HSA-2161567 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 IEA Homo sapiens 15647 R-HSA-266072 https://reactome.org/PathwayBrowser/#/R-HSA-266072 LTA4 is hydolysed to LTB4 by LTA4H TAS Homo sapiens 15647 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15647 R-HSA-391941 https://reactome.org/PathwayBrowser/#/R-HSA-391941 BLT receptors can bind LTB4 TAS Homo sapiens 15647 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15647 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15647 R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus 15647 R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 15647 R-MMU-266072 https://reactome.org/PathwayBrowser/#/R-MMU-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Mus musculus 15647 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15647 R-MMU-391941 https://reactome.org/PathwayBrowser/#/R-MMU-391941 BLT receptors can bind LTB4 IEA Mus musculus 15647 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15647 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15647 R-RNO-211873 https://reactome.org/PathwayBrowser/#/R-RNO-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Rattus norvegicus 15647 R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 15647 R-RNO-266072 https://reactome.org/PathwayBrowser/#/R-RNO-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Rattus norvegicus 15647 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15647 R-RNO-391941 https://reactome.org/PathwayBrowser/#/R-RNO-391941 BLT receptors can bind LTB4 IEA Rattus norvegicus 15647 R-SCE-266072 https://reactome.org/PathwayBrowser/#/R-SCE-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Saccharomyces cerevisiae 15647 R-SPO-266072 https://reactome.org/PathwayBrowser/#/R-SPO-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Schizosaccharomyces pombe 15647 R-SSC-211873 https://reactome.org/PathwayBrowser/#/R-SSC-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Sus scrofa 15647 R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa 15647 R-SSC-2161617 https://reactome.org/PathwayBrowser/#/R-SSC-2161617 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 TAS Sus scrofa 15647 R-SSC-266072 https://reactome.org/PathwayBrowser/#/R-SSC-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Sus scrofa 15647 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15647 R-SSC-391941 https://reactome.org/PathwayBrowser/#/R-SSC-391941 BLT receptors can bind LTB4 IEA Sus scrofa 15647 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15647 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15647 R-XTR-211873 https://reactome.org/PathwayBrowser/#/R-XTR-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Xenopus tropicalis 15647 R-XTR-215526 https://reactome.org/PathwayBrowser/#/R-XTR-215526 CYP4F3 20-hydroxylates LTB4 IEA Xenopus tropicalis 15647 R-XTR-266072 https://reactome.org/PathwayBrowser/#/R-XTR-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Xenopus tropicalis 15647 R-XTR-391941 https://reactome.org/PathwayBrowser/#/R-XTR-391941 BLT receptors can bind LTB4 IEA Xenopus tropicalis 15647 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 15647 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15650 R-BTA-266012 https://reactome.org/PathwayBrowser/#/R-BTA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Bos taurus 15650 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15650 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 15650 R-BTA-391937 https://reactome.org/PathwayBrowser/#/R-BTA-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Bos taurus 15650 R-BTA-391943 https://reactome.org/PathwayBrowser/#/R-BTA-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Bos taurus 15650 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15650 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15650 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 15650 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 15650 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 15650 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 15650 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 15650 R-CEL-391937 https://reactome.org/PathwayBrowser/#/R-CEL-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Caenorhabditis elegans 15650 R-CEL-391943 https://reactome.org/PathwayBrowser/#/R-CEL-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 15650 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 15650 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15650 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 15650 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 15650 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 15650 R-CFA-266012 https://reactome.org/PathwayBrowser/#/R-CFA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Canis familiaris 15650 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15650 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 15650 R-CFA-391937 https://reactome.org/PathwayBrowser/#/R-CFA-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Canis familiaris 15650 R-CFA-391943 https://reactome.org/PathwayBrowser/#/R-CFA-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Canis familiaris 15650 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15650 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15650 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 15650 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 15650 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 15650 R-DME-266012 https://reactome.org/PathwayBrowser/#/R-DME-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Drosophila melanogaster 15650 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 15650 R-DME-391943 https://reactome.org/PathwayBrowser/#/R-DME-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 15650 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 15650 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15650 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 15650 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 15650 R-DRE-391943 https://reactome.org/PathwayBrowser/#/R-DRE-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Danio rerio 15650 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 15650 R-GGA-266012 https://reactome.org/PathwayBrowser/#/R-GGA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Gallus gallus 15650 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 15650 R-GGA-391943 https://reactome.org/PathwayBrowser/#/R-GGA-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Gallus gallus 15650 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 15650 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15650 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 15650 R-HSA-266012 https://reactome.org/PathwayBrowser/#/R-HSA-266012 LTD4 is converted to LTE4 by DPEP1/2 TAS Homo sapiens 15650 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15650 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 15650 R-HSA-391937 https://reactome.org/PathwayBrowser/#/R-HSA-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes TAS Homo sapiens 15650 R-HSA-391943 https://reactome.org/PathwayBrowser/#/R-HSA-391943 CYSLT2 binds LTC4,LTD4,LTE4 TAS Homo sapiens 15650 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15650 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15650 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 15650 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 15650 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 15650 R-MMU-266012 https://reactome.org/PathwayBrowser/#/R-MMU-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Mus musculus 15650 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15650 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 15650 R-MMU-391937 https://reactome.org/PathwayBrowser/#/R-MMU-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Mus musculus 15650 R-MMU-391943 https://reactome.org/PathwayBrowser/#/R-MMU-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Mus musculus 15650 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15650 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15650 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 15650 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 15650 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 15650 R-RNO-266012 https://reactome.org/PathwayBrowser/#/R-RNO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Rattus norvegicus 15650 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15650 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 15650 R-RNO-391937 https://reactome.org/PathwayBrowser/#/R-RNO-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Rattus norvegicus 15650 R-RNO-391943 https://reactome.org/PathwayBrowser/#/R-RNO-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 15650 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 15650 R-SPO-266012 https://reactome.org/PathwayBrowser/#/R-SPO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Schizosaccharomyces pombe 15650 R-SSC-266012 https://reactome.org/PathwayBrowser/#/R-SSC-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Sus scrofa 15650 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15650 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 15650 R-SSC-391937 https://reactome.org/PathwayBrowser/#/R-SSC-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Sus scrofa 15650 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15650 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15650 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 15650 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 15650 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 15650 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15651 R-BTA-2161775 https://reactome.org/PathwayBrowser/#/R-BTA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Bos taurus 15651 R-BTA-2162019 https://reactome.org/PathwayBrowser/#/R-BTA-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Bos taurus 15651 R-BTA-266050 https://reactome.org/PathwayBrowser/#/R-BTA-266050 LTA4 is converted to LTC4 by LTC4S IEA Bos taurus 15651 R-BTA-266051 https://reactome.org/PathwayBrowser/#/R-BTA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Bos taurus 15651 R-BTA-266072 https://reactome.org/PathwayBrowser/#/R-BTA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Bos taurus 15651 R-CEL-266072 https://reactome.org/PathwayBrowser/#/R-CEL-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Caenorhabditis elegans 15651 R-CFA-2161775 https://reactome.org/PathwayBrowser/#/R-CFA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Canis familiaris 15651 R-CFA-2162019 https://reactome.org/PathwayBrowser/#/R-CFA-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Canis familiaris 15651 R-CFA-266050 https://reactome.org/PathwayBrowser/#/R-CFA-266050 LTA4 is converted to LTC4 by LTC4S IEA Canis familiaris 15651 R-CFA-266051 https://reactome.org/PathwayBrowser/#/R-CFA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Canis familiaris 15651 R-CFA-266072 https://reactome.org/PathwayBrowser/#/R-CFA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Canis familiaris 15651 R-DDI-2161775 https://reactome.org/PathwayBrowser/#/R-DDI-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Dictyostelium discoideum 15651 R-DDI-2162019 https://reactome.org/PathwayBrowser/#/R-DDI-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Dictyostelium discoideum 15651 R-DDI-266050 https://reactome.org/PathwayBrowser/#/R-DDI-266050 LTA4 is converted to LTC4 by LTC4S IEA Dictyostelium discoideum 15651 R-DDI-266051 https://reactome.org/PathwayBrowser/#/R-DDI-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Dictyostelium discoideum 15651 R-DDI-266072 https://reactome.org/PathwayBrowser/#/R-DDI-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Dictyostelium discoideum 15651 R-DME-266072 https://reactome.org/PathwayBrowser/#/R-DME-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Drosophila melanogaster 15651 R-DRE-2161775 https://reactome.org/PathwayBrowser/#/R-DRE-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Danio rerio 15651 R-DRE-2162019 https://reactome.org/PathwayBrowser/#/R-DRE-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Danio rerio 15651 R-DRE-266072 https://reactome.org/PathwayBrowser/#/R-DRE-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Danio rerio 15651 R-GGA-266050 https://reactome.org/PathwayBrowser/#/R-GGA-266050 LTA4 is converted to LTC4 by LTC4S IEA Gallus gallus 15651 R-GGA-266051 https://reactome.org/PathwayBrowser/#/R-GGA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Gallus gallus 15651 R-GGA-266072 https://reactome.org/PathwayBrowser/#/R-GGA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Gallus gallus 15651 R-HSA-2161775 https://reactome.org/PathwayBrowser/#/R-HSA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 TAS Homo sapiens 15651 R-HSA-2161962 https://reactome.org/PathwayBrowser/#/R-HSA-2161962 LTA4 is hydrolysed to 6t-/6t,12epi-LTB4 TAS Homo sapiens 15651 R-HSA-2162019 https://reactome.org/PathwayBrowser/#/R-HSA-2162019 LTA4 is converted to EXA4 by ALOX15 TAS Homo sapiens 15651 R-HSA-266050 https://reactome.org/PathwayBrowser/#/R-HSA-266050 LTA4 is converted to LTC4 by LTC4S TAS Homo sapiens 15651 R-HSA-266051 https://reactome.org/PathwayBrowser/#/R-HSA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 TAS Homo sapiens 15651 R-HSA-266072 https://reactome.org/PathwayBrowser/#/R-HSA-266072 LTA4 is hydolysed to LTB4 by LTA4H TAS Homo sapiens 15651 R-HSA-9032036 https://reactome.org/PathwayBrowser/#/R-HSA-9032036 LTA4 translocates from neutrophil cytosol to platelet cytosol TAS Homo sapiens 15651 R-MMU-2161775 https://reactome.org/PathwayBrowser/#/R-MMU-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Mus musculus 15651 R-MMU-2162019 https://reactome.org/PathwayBrowser/#/R-MMU-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Mus musculus 15651 R-MMU-266050 https://reactome.org/PathwayBrowser/#/R-MMU-266050 LTA4 is converted to LTC4 by LTC4S IEA Mus musculus 15651 R-MMU-266051 https://reactome.org/PathwayBrowser/#/R-MMU-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Mus musculus 15651 R-MMU-266072 https://reactome.org/PathwayBrowser/#/R-MMU-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Mus musculus 15651 R-RNO-2161775 https://reactome.org/PathwayBrowser/#/R-RNO-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Rattus norvegicus 15651 R-RNO-2162019 https://reactome.org/PathwayBrowser/#/R-RNO-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Rattus norvegicus 15651 R-RNO-266050 https://reactome.org/PathwayBrowser/#/R-RNO-266050 LTA4 is converted to LTC4 by LTC4S IEA Rattus norvegicus 15651 R-RNO-266051 https://reactome.org/PathwayBrowser/#/R-RNO-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Rattus norvegicus 15651 R-RNO-266072 https://reactome.org/PathwayBrowser/#/R-RNO-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Rattus norvegicus 15651 R-SCE-266072 https://reactome.org/PathwayBrowser/#/R-SCE-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Saccharomyces cerevisiae 15651 R-SPO-266072 https://reactome.org/PathwayBrowser/#/R-SPO-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Schizosaccharomyces pombe 15651 R-SSC-2161775 https://reactome.org/PathwayBrowser/#/R-SSC-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Sus scrofa 15651 R-SSC-2162019 https://reactome.org/PathwayBrowser/#/R-SSC-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Sus scrofa 15651 R-SSC-266050 https://reactome.org/PathwayBrowser/#/R-SSC-266050 LTA4 is converted to LTC4 by LTC4S IEA Sus scrofa 15651 R-SSC-266051 https://reactome.org/PathwayBrowser/#/R-SSC-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Sus scrofa 15651 R-SSC-266072 https://reactome.org/PathwayBrowser/#/R-SSC-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Sus scrofa 15651 R-XTR-266050 https://reactome.org/PathwayBrowser/#/R-XTR-266050 LTA4 is converted to LTC4 by LTC4S IEA Xenopus tropicalis 15651 R-XTR-266051 https://reactome.org/PathwayBrowser/#/R-XTR-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Xenopus tropicalis 15651 R-XTR-266072 https://reactome.org/PathwayBrowser/#/R-XTR-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Xenopus tropicalis 15698 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 15698 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 15698 R-BTA-109759 https://reactome.org/PathwayBrowser/#/R-BTA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Bos taurus 15698 R-BTA-73598 https://reactome.org/PathwayBrowser/#/R-BTA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Bos taurus 15698 R-BTA-73608 https://reactome.org/PathwayBrowser/#/R-BTA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Bos taurus 15698 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 15698 R-CEL-73608 https://reactome.org/PathwayBrowser/#/R-CEL-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Caenorhabditis elegans 15698 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 15698 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 15698 R-CFA-109759 https://reactome.org/PathwayBrowser/#/R-CFA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Canis familiaris 15698 R-CFA-73598 https://reactome.org/PathwayBrowser/#/R-CFA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Canis familiaris 15698 R-CFA-73608 https://reactome.org/PathwayBrowser/#/R-CFA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Canis familiaris 15698 R-DDI-73608 https://reactome.org/PathwayBrowser/#/R-DDI-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Dictyostelium discoideum 15698 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 15698 R-DME-109759 https://reactome.org/PathwayBrowser/#/R-DME-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Drosophila melanogaster 15698 R-DME-73608 https://reactome.org/PathwayBrowser/#/R-DME-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Drosophila melanogaster 15698 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 15698 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 15698 R-DRE-73598 https://reactome.org/PathwayBrowser/#/R-DRE-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Danio rerio 15698 R-DRE-73608 https://reactome.org/PathwayBrowser/#/R-DRE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Danio rerio 15698 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 15698 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 15698 R-GGA-109759 https://reactome.org/PathwayBrowser/#/R-GGA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Gallus gallus 15698 R-GGA-73598 https://reactome.org/PathwayBrowser/#/R-GGA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Gallus gallus 15698 R-GGA-73608 https://reactome.org/PathwayBrowser/#/R-GGA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Gallus gallus 15698 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 15698 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 15698 R-HSA-109759 https://reactome.org/PathwayBrowser/#/R-HSA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] TAS Homo sapiens 15698 R-HSA-73598 https://reactome.org/PathwayBrowser/#/R-HSA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) TAS Homo sapiens 15698 R-HSA-73608 https://reactome.org/PathwayBrowser/#/R-HSA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) TAS Homo sapiens 15698 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 15698 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 15698 R-MMU-109759 https://reactome.org/PathwayBrowser/#/R-MMU-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Mus musculus 15698 R-MMU-73598 https://reactome.org/PathwayBrowser/#/R-MMU-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Mus musculus 15698 R-MMU-73608 https://reactome.org/PathwayBrowser/#/R-MMU-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Mus musculus 15698 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 15698 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 15698 R-RNO-109759 https://reactome.org/PathwayBrowser/#/R-RNO-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Rattus norvegicus 15698 R-RNO-73598 https://reactome.org/PathwayBrowser/#/R-RNO-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Rattus norvegicus 15698 R-RNO-73608 https://reactome.org/PathwayBrowser/#/R-RNO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Rattus norvegicus 15698 R-SCE-73608 https://reactome.org/PathwayBrowser/#/R-SCE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Saccharomyces cerevisiae 15698 R-SPO-73608 https://reactome.org/PathwayBrowser/#/R-SPO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Schizosaccharomyces pombe 15698 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 15698 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 15698 R-SSC-109759 https://reactome.org/PathwayBrowser/#/R-SSC-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Sus scrofa 15698 R-SSC-73608 https://reactome.org/PathwayBrowser/#/R-SSC-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Sus scrofa 15698 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 15698 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 15698 R-XTR-109759 https://reactome.org/PathwayBrowser/#/R-XTR-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Xenopus tropicalis 15698 R-XTR-73598 https://reactome.org/PathwayBrowser/#/R-XTR-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Xenopus tropicalis 15698 R-XTR-73608 https://reactome.org/PathwayBrowser/#/R-XTR-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Xenopus tropicalis 15710 R-BTA-6797955 https://reactome.org/PathwayBrowser/#/R-BTA-6797955 ALDH7A1 oxidises BETALD to BET IEA Bos taurus 15710 R-BTA-6797961 https://reactome.org/PathwayBrowser/#/R-BTA-6797961 CHDH oxidises Cho to BETALD IEA Bos taurus 15710 R-CEL-6797955 https://reactome.org/PathwayBrowser/#/R-CEL-6797955 ALDH7A1 oxidises BETALD to BET IEA Caenorhabditis elegans 15710 R-CEL-6797961 https://reactome.org/PathwayBrowser/#/R-CEL-6797961 CHDH oxidises Cho to BETALD IEA Caenorhabditis elegans 15710 R-CFA-6797955 https://reactome.org/PathwayBrowser/#/R-CFA-6797955 ALDH7A1 oxidises BETALD to BET IEA Canis familiaris 15710 R-CFA-6797961 https://reactome.org/PathwayBrowser/#/R-CFA-6797961 CHDH oxidises Cho to BETALD IEA Canis familiaris 15710 R-DDI-6797955 https://reactome.org/PathwayBrowser/#/R-DDI-6797955 ALDH7A1 oxidises BETALD to BET IEA Dictyostelium discoideum 15710 R-DDI-6797961 https://reactome.org/PathwayBrowser/#/R-DDI-6797961 CHDH oxidises Cho to BETALD IEA Dictyostelium discoideum 15710 R-DME-6797955 https://reactome.org/PathwayBrowser/#/R-DME-6797955 ALDH7A1 oxidises BETALD to BET IEA Drosophila melanogaster 15710 R-DME-6797961 https://reactome.org/PathwayBrowser/#/R-DME-6797961 CHDH oxidises Cho to BETALD IEA Drosophila melanogaster 15710 R-DRE-6797955 https://reactome.org/PathwayBrowser/#/R-DRE-6797955 ALDH7A1 oxidises BETALD to BET IEA Danio rerio 15710 R-GGA-6797955 https://reactome.org/PathwayBrowser/#/R-GGA-6797955 ALDH7A1 oxidises BETALD to BET IEA Gallus gallus 15710 R-GGA-6797961 https://reactome.org/PathwayBrowser/#/R-GGA-6797961 CHDH oxidises Cho to BETALD IEA Gallus gallus 15710 R-HSA-6797955 https://reactome.org/PathwayBrowser/#/R-HSA-6797955 ALDH7A1 oxidises BETALD to BET TAS Homo sapiens 15710 R-HSA-6797961 https://reactome.org/PathwayBrowser/#/R-HSA-6797961 CHDH oxidises Cho to BETALD TAS Homo sapiens 15710 R-MMU-6797955 https://reactome.org/PathwayBrowser/#/R-MMU-6797955 ALDH7A1 oxidises BETALD to BET IEA Mus musculus 15710 R-MMU-6797961 https://reactome.org/PathwayBrowser/#/R-MMU-6797961 CHDH oxidises Cho to BETALD IEA Mus musculus 15710 R-RNO-6797955 https://reactome.org/PathwayBrowser/#/R-RNO-6797955 ALDH7A1 oxidises BETALD to BET IEA Rattus norvegicus 15710 R-RNO-6797961 https://reactome.org/PathwayBrowser/#/R-RNO-6797961 CHDH oxidises Cho to BETALD IEA Rattus norvegicus 15710 R-SSC-6797955 https://reactome.org/PathwayBrowser/#/R-SSC-6797955 ALDH7A1 oxidises BETALD to BET IEA Sus scrofa 15710 R-SSC-6797961 https://reactome.org/PathwayBrowser/#/R-SSC-6797961 CHDH oxidises Cho to BETALD IEA Sus scrofa 15710 R-XTR-6797955 https://reactome.org/PathwayBrowser/#/R-XTR-6797955 ALDH7A1 oxidises BETALD to BET IEA Xenopus tropicalis 15721 R-BTA-163741 https://reactome.org/PathwayBrowser/#/R-BTA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Bos taurus 15721 R-BTA-163764 https://reactome.org/PathwayBrowser/#/R-BTA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 15721 R-BTA-71324 https://reactome.org/PathwayBrowser/#/R-BTA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 15721 R-BTA-71334 https://reactome.org/PathwayBrowser/#/R-BTA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Bos taurus 15721 R-BTA-8959719 https://reactome.org/PathwayBrowser/#/R-BTA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Bos taurus 15721 R-CEL-163741 https://reactome.org/PathwayBrowser/#/R-CEL-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Caenorhabditis elegans 15721 R-CEL-163764 https://reactome.org/PathwayBrowser/#/R-CEL-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 15721 R-CEL-71324 https://reactome.org/PathwayBrowser/#/R-CEL-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 15721 R-CEL-71334 https://reactome.org/PathwayBrowser/#/R-CEL-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Caenorhabditis elegans 15721 R-CEL-8959719 https://reactome.org/PathwayBrowser/#/R-CEL-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Caenorhabditis elegans 15721 R-CFA-163741 https://reactome.org/PathwayBrowser/#/R-CFA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Canis familiaris 15721 R-CFA-163764 https://reactome.org/PathwayBrowser/#/R-CFA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 15721 R-CFA-71324 https://reactome.org/PathwayBrowser/#/R-CFA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 15721 R-CFA-71334 https://reactome.org/PathwayBrowser/#/R-CFA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Canis familiaris 15721 R-CFA-8959719 https://reactome.org/PathwayBrowser/#/R-CFA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Canis familiaris 15721 R-DDI-163764 https://reactome.org/PathwayBrowser/#/R-DDI-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 15721 R-DDI-71334 https://reactome.org/PathwayBrowser/#/R-DDI-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Dictyostelium discoideum 15721 R-DME-163741 https://reactome.org/PathwayBrowser/#/R-DME-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Drosophila melanogaster 15721 R-DME-163764 https://reactome.org/PathwayBrowser/#/R-DME-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 15721 R-DME-71324 https://reactome.org/PathwayBrowser/#/R-DME-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 15721 R-DME-71334 https://reactome.org/PathwayBrowser/#/R-DME-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Drosophila melanogaster 15721 R-DRE-163764 https://reactome.org/PathwayBrowser/#/R-DRE-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Danio rerio 15721 R-DRE-71334 https://reactome.org/PathwayBrowser/#/R-DRE-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Danio rerio 15721 R-GGA-163741 https://reactome.org/PathwayBrowser/#/R-GGA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Gallus gallus 15721 R-GGA-163764 https://reactome.org/PathwayBrowser/#/R-GGA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 15721 R-GGA-71324 https://reactome.org/PathwayBrowser/#/R-GGA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 15721 R-GGA-71334 https://reactome.org/PathwayBrowser/#/R-GGA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Gallus gallus 15721 R-GGA-8959719 https://reactome.org/PathwayBrowser/#/R-GGA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Gallus gallus 15721 R-HSA-163741 https://reactome.org/PathwayBrowser/#/R-HSA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate TAS Homo sapiens 15721 R-HSA-163764 https://reactome.org/PathwayBrowser/#/R-HSA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 15721 R-HSA-5659989 https://reactome.org/PathwayBrowser/#/R-HSA-5659989 Defective TALDO1 does not transform SH7P, GA3P to Fru(6)P, E4P TAS Homo sapiens 15721 R-HSA-71324 https://reactome.org/PathwayBrowser/#/R-HSA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 15721 R-HSA-71334 https://reactome.org/PathwayBrowser/#/R-HSA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate TAS Homo sapiens 15721 R-HSA-8959719 https://reactome.org/PathwayBrowser/#/R-HSA-8959719 SHPK phosphorylates Sedo to Sedo7P TAS Homo sapiens 15721 R-MMU-163741 https://reactome.org/PathwayBrowser/#/R-MMU-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Mus musculus 15721 R-MMU-163764 https://reactome.org/PathwayBrowser/#/R-MMU-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 15721 R-MMU-71324 https://reactome.org/PathwayBrowser/#/R-MMU-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 15721 R-MMU-71334 https://reactome.org/PathwayBrowser/#/R-MMU-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Mus musculus 15721 R-MMU-8959719 https://reactome.org/PathwayBrowser/#/R-MMU-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Mus musculus 15721 R-RNO-163741 https://reactome.org/PathwayBrowser/#/R-RNO-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Rattus norvegicus 15721 R-RNO-163764 https://reactome.org/PathwayBrowser/#/R-RNO-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 15721 R-RNO-71324 https://reactome.org/PathwayBrowser/#/R-RNO-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 15721 R-RNO-71334 https://reactome.org/PathwayBrowser/#/R-RNO-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Rattus norvegicus 15721 R-RNO-8959719 https://reactome.org/PathwayBrowser/#/R-RNO-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Rattus norvegicus 15721 R-SCE-163764 https://reactome.org/PathwayBrowser/#/R-SCE-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Saccharomyces cerevisiae 15721 R-SCE-71334 https://reactome.org/PathwayBrowser/#/R-SCE-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Saccharomyces cerevisiae 15721 R-SPO-163764 https://reactome.org/PathwayBrowser/#/R-SPO-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Schizosaccharomyces pombe 15721 R-SPO-71334 https://reactome.org/PathwayBrowser/#/R-SPO-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Schizosaccharomyces pombe 15721 R-SSC-163741 https://reactome.org/PathwayBrowser/#/R-SSC-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Sus scrofa 15721 R-SSC-163764 https://reactome.org/PathwayBrowser/#/R-SSC-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 15721 R-SSC-71324 https://reactome.org/PathwayBrowser/#/R-SSC-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 15721 R-SSC-71334 https://reactome.org/PathwayBrowser/#/R-SSC-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Sus scrofa 15721 R-SSC-8959719 https://reactome.org/PathwayBrowser/#/R-SSC-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Sus scrofa 15721 R-XTR-163741 https://reactome.org/PathwayBrowser/#/R-XTR-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Xenopus tropicalis 15721 R-XTR-163764 https://reactome.org/PathwayBrowser/#/R-XTR-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 15721 R-XTR-71324 https://reactome.org/PathwayBrowser/#/R-XTR-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 15721 R-XTR-71334 https://reactome.org/PathwayBrowser/#/R-XTR-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Xenopus tropicalis 15721 R-XTR-8959719 https://reactome.org/PathwayBrowser/#/R-XTR-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Xenopus tropicalis 15724 R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 15724 R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 15724 R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 15724 R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 15724 R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 15724 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 15724 R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 15724 R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 15724 R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 15724 R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 15724 R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 15725 R-BTA-204617 https://reactome.org/PathwayBrowser/#/R-BTA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Bos taurus 15725 R-BTA-204647 https://reactome.org/PathwayBrowser/#/R-BTA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Bos taurus 15725 R-CEL-204617 https://reactome.org/PathwayBrowser/#/R-CEL-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Caenorhabditis elegans 15725 R-CEL-204647 https://reactome.org/PathwayBrowser/#/R-CEL-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Caenorhabditis elegans 15725 R-CFA-204617 https://reactome.org/PathwayBrowser/#/R-CFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Canis familiaris 15725 R-CFA-204647 https://reactome.org/PathwayBrowser/#/R-CFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Canis familiaris 15725 R-DDI-204617 https://reactome.org/PathwayBrowser/#/R-DDI-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Dictyostelium discoideum 15725 R-DDI-204647 https://reactome.org/PathwayBrowser/#/R-DDI-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Dictyostelium discoideum 15725 R-DME-204617 https://reactome.org/PathwayBrowser/#/R-DME-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Drosophila melanogaster 15725 R-DME-204647 https://reactome.org/PathwayBrowser/#/R-DME-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Drosophila melanogaster 15725 R-DRE-204617 https://reactome.org/PathwayBrowser/#/R-DRE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Danio rerio 15725 R-DRE-204647 https://reactome.org/PathwayBrowser/#/R-DRE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Danio rerio 15725 R-HSA-204617 https://reactome.org/PathwayBrowser/#/R-HSA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A TAS Homo sapiens 15725 R-HSA-204647 https://reactome.org/PathwayBrowser/#/R-HSA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine TAS Homo sapiens 15725 R-MMU-204617 https://reactome.org/PathwayBrowser/#/R-MMU-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Mus musculus 15725 R-MMU-204647 https://reactome.org/PathwayBrowser/#/R-MMU-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Mus musculus 15725 R-PFA-204617 https://reactome.org/PathwayBrowser/#/R-PFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Plasmodium falciparum 15725 R-PFA-204647 https://reactome.org/PathwayBrowser/#/R-PFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Plasmodium falciparum 15725 R-RNO-204617 https://reactome.org/PathwayBrowser/#/R-RNO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Rattus norvegicus 15725 R-RNO-204647 https://reactome.org/PathwayBrowser/#/R-RNO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Rattus norvegicus 15725 R-SCE-204617 https://reactome.org/PathwayBrowser/#/R-SCE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Saccharomyces cerevisiae 15725 R-SCE-204647 https://reactome.org/PathwayBrowser/#/R-SCE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Saccharomyces cerevisiae 15725 R-SPO-204617 https://reactome.org/PathwayBrowser/#/R-SPO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Schizosaccharomyces pombe 15725 R-SPO-204647 https://reactome.org/PathwayBrowser/#/R-SPO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Schizosaccharomyces pombe 15725 R-SSC-204617 https://reactome.org/PathwayBrowser/#/R-SSC-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Sus scrofa 15725 R-SSC-204647 https://reactome.org/PathwayBrowser/#/R-SSC-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Sus scrofa 15725 R-XTR-204617 https://reactome.org/PathwayBrowser/#/R-XTR-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Xenopus tropicalis 15725 R-XTR-204647 https://reactome.org/PathwayBrowser/#/R-XTR-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Xenopus tropicalis 15735 R-MTU-879245 https://reactome.org/PathwayBrowser/#/R-MTU-879245 mycothiol binds formaldehyde and is dehydrogenated TAS Mycobacterium tuberculosis 15735 R-MTU-879293 https://reactome.org/PathwayBrowser/#/R-MTU-879293 formylmycothiol hydrolyzes into mycothiol and formate TAS Mycobacterium tuberculosis 15740 R-BTA-1237119 https://reactome.org/PathwayBrowser/#/R-BTA-1237119 Acireductone is oxidized to MOB IEA Bos taurus 15740 R-BTA-1474146 https://reactome.org/PathwayBrowser/#/R-BTA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Bos taurus 15740 R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 15740 R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 15740 R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 15740 R-BTA-200711 https://reactome.org/PathwayBrowser/#/R-BTA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Bos taurus 15740 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15740 R-BTA-444047 https://reactome.org/PathwayBrowser/#/R-BTA-444047 Receptor FFAR3 binds carboxylates IEA Bos taurus 15740 R-BTA-444171 https://reactome.org/PathwayBrowser/#/R-BTA-444171 Receptor FFAR2 binds carboxylates IEA Bos taurus 15740 R-BTA-5693724 https://reactome.org/PathwayBrowser/#/R-BTA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Bos taurus 15740 R-BTA-5696839 https://reactome.org/PathwayBrowser/#/R-BTA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Bos taurus 15740 R-BTA-6801456 https://reactome.org/PathwayBrowser/#/R-BTA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Bos taurus 15740 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15740 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15740 R-CEL-1237119 https://reactome.org/PathwayBrowser/#/R-CEL-1237119 Acireductone is oxidized to MOB IEA Caenorhabditis elegans 15740 R-CEL-1474146 https://reactome.org/PathwayBrowser/#/R-CEL-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Caenorhabditis elegans 15740 R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 15740 R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 15740 R-CEL-200711 https://reactome.org/PathwayBrowser/#/R-CEL-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Caenorhabditis elegans 15740 R-CEL-5693724 https://reactome.org/PathwayBrowser/#/R-CEL-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Caenorhabditis elegans 15740 R-CEL-5696839 https://reactome.org/PathwayBrowser/#/R-CEL-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Caenorhabditis elegans 15740 R-CEL-6801456 https://reactome.org/PathwayBrowser/#/R-CEL-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Caenorhabditis elegans 15740 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15740 R-CFA-1237119 https://reactome.org/PathwayBrowser/#/R-CFA-1237119 Acireductone is oxidized to MOB IEA Canis familiaris 15740 R-CFA-1474146 https://reactome.org/PathwayBrowser/#/R-CFA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Canis familiaris 15740 R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 15740 R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 15740 R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 15740 R-CFA-200711 https://reactome.org/PathwayBrowser/#/R-CFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Canis familiaris 15740 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15740 R-CFA-444047 https://reactome.org/PathwayBrowser/#/R-CFA-444047 Receptor FFAR3 binds carboxylates IEA Canis familiaris 15740 R-CFA-444171 https://reactome.org/PathwayBrowser/#/R-CFA-444171 Receptor FFAR2 binds carboxylates IEA Canis familiaris 15740 R-CFA-5693724 https://reactome.org/PathwayBrowser/#/R-CFA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Canis familiaris 15740 R-CFA-5696839 https://reactome.org/PathwayBrowser/#/R-CFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Canis familiaris 15740 R-CFA-6801456 https://reactome.org/PathwayBrowser/#/R-CFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Canis familiaris 15740 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15740 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15740 R-DDI-1237119 https://reactome.org/PathwayBrowser/#/R-DDI-1237119 Acireductone is oxidized to MOB IEA Dictyostelium discoideum 15740 R-DDI-1474146 https://reactome.org/PathwayBrowser/#/R-DDI-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Dictyostelium discoideum 15740 R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 15740 R-DDI-200711 https://reactome.org/PathwayBrowser/#/R-DDI-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Dictyostelium discoideum 15740 R-DDI-5693724 https://reactome.org/PathwayBrowser/#/R-DDI-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Dictyostelium discoideum 15740 R-DDI-5696839 https://reactome.org/PathwayBrowser/#/R-DDI-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Dictyostelium discoideum 15740 R-DDI-6801456 https://reactome.org/PathwayBrowser/#/R-DDI-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Dictyostelium discoideum 15740 R-DME-1237119 https://reactome.org/PathwayBrowser/#/R-DME-1237119 Acireductone is oxidized to MOB IEA Drosophila melanogaster 15740 R-DME-1474146 https://reactome.org/PathwayBrowser/#/R-DME-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Drosophila melanogaster 15740 R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 15740 R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 15740 R-DME-200711 https://reactome.org/PathwayBrowser/#/R-DME-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Drosophila melanogaster 15740 R-DME-5693724 https://reactome.org/PathwayBrowser/#/R-DME-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Drosophila melanogaster 15740 R-DME-5696839 https://reactome.org/PathwayBrowser/#/R-DME-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Drosophila melanogaster 15740 R-DME-6801456 https://reactome.org/PathwayBrowser/#/R-DME-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Drosophila melanogaster 15740 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15740 R-DRE-1237119 https://reactome.org/PathwayBrowser/#/R-DRE-1237119 Acireductone is oxidized to MOB IEA Danio rerio 15740 R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 15740 R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 15740 R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 15740 R-DRE-200711 https://reactome.org/PathwayBrowser/#/R-DRE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Danio rerio 15740 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 15740 R-DRE-444047 https://reactome.org/PathwayBrowser/#/R-DRE-444047 Receptor FFAR3 binds carboxylates IEA Danio rerio 15740 R-DRE-444171 https://reactome.org/PathwayBrowser/#/R-DRE-444171 Receptor FFAR2 binds carboxylates IEA Danio rerio 15740 R-DRE-5693724 https://reactome.org/PathwayBrowser/#/R-DRE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Danio rerio 15740 R-DRE-5696839 https://reactome.org/PathwayBrowser/#/R-DRE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Danio rerio 15740 R-DRE-6801456 https://reactome.org/PathwayBrowser/#/R-DRE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Danio rerio 15740 R-GGA-1237119 https://reactome.org/PathwayBrowser/#/R-GGA-1237119 Acireductone is oxidized to MOB IEA Gallus gallus 15740 R-GGA-1474146 https://reactome.org/PathwayBrowser/#/R-GGA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Gallus gallus 15740 R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 15740 R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 15740 R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 15740 R-GGA-200711 https://reactome.org/PathwayBrowser/#/R-GGA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Gallus gallus 15740 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 15740 R-GGA-444171 https://reactome.org/PathwayBrowser/#/R-GGA-444171 Receptor FFAR2 binds carboxylates IEA Gallus gallus 15740 R-GGA-5693724 https://reactome.org/PathwayBrowser/#/R-GGA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Gallus gallus 15740 R-GGA-5696839 https://reactome.org/PathwayBrowser/#/R-GGA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Gallus gallus 15740 R-GGA-6801456 https://reactome.org/PathwayBrowser/#/R-GGA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Gallus gallus 15740 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 15740 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15740 R-HSA-1237119 https://reactome.org/PathwayBrowser/#/R-HSA-1237119 Acireductone is oxidized to MOB TAS Homo sapiens 15740 R-HSA-1474146 https://reactome.org/PathwayBrowser/#/R-HSA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate TAS Homo sapiens 15740 R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 15740 R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 15740 R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 15740 R-HSA-200711 https://reactome.org/PathwayBrowser/#/R-HSA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG TAS Homo sapiens 15740 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15740 R-HSA-389580 https://reactome.org/PathwayBrowser/#/R-HSA-389580 formyl-CoA + H2O => formate + CoASH TAS Homo sapiens 15740 R-HSA-444047 https://reactome.org/PathwayBrowser/#/R-HSA-444047 Receptor FFAR3 binds carboxylates TAS Homo sapiens 15740 R-HSA-444171 https://reactome.org/PathwayBrowser/#/R-HSA-444171 Receptor FFAR2 binds carboxylates TAS Homo sapiens 15740 R-HSA-5693724 https://reactome.org/PathwayBrowser/#/R-HSA-5693724 ESD dimer hydrolyses S-FGSH to GSH TAS Homo sapiens 15740 R-HSA-5696839 https://reactome.org/PathwayBrowser/#/R-HSA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF TAS Homo sapiens 15740 R-HSA-6801456 https://reactome.org/PathwayBrowser/#/R-HSA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF TAS Homo sapiens 15740 R-HSA-6803255 https://reactome.org/PathwayBrowser/#/R-HSA-6803255 HCOOH translocated from mitochondrial matrix to cytosol TAS Homo sapiens 15740 R-HSA-71189 https://reactome.org/PathwayBrowser/#/R-HSA-71189 AFMID hydrolyses NFK to L-KYN IEA Homo sapiens 15740 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15740 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15740 R-MMU-1237119 https://reactome.org/PathwayBrowser/#/R-MMU-1237119 Acireductone is oxidized to MOB IEA Mus musculus 15740 R-MMU-1474146 https://reactome.org/PathwayBrowser/#/R-MMU-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Mus musculus 15740 R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 15740 R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 15740 R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 15740 R-MMU-200711 https://reactome.org/PathwayBrowser/#/R-MMU-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Mus musculus 15740 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15740 R-MMU-444047 https://reactome.org/PathwayBrowser/#/R-MMU-444047 Receptor FFAR3 binds carboxylates IEA Mus musculus 15740 R-MMU-444171 https://reactome.org/PathwayBrowser/#/R-MMU-444171 Receptor FFAR2 binds carboxylates IEA Mus musculus 15740 R-MMU-5693724 https://reactome.org/PathwayBrowser/#/R-MMU-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Mus musculus 15740 R-MMU-5696839 https://reactome.org/PathwayBrowser/#/R-MMU-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Mus musculus 15740 R-MMU-6801456 https://reactome.org/PathwayBrowser/#/R-MMU-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Mus musculus 15740 R-MMU-71196 https://reactome.org/PathwayBrowser/#/R-MMU-71196 N-formylkynurenine + H2O => kynurenine + formate [mouse] TAS Mus musculus 15740 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15740 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15740 R-MTU-879293 https://reactome.org/PathwayBrowser/#/R-MTU-879293 formylmycothiol hydrolyzes into mycothiol and formate TAS Mycobacterium tuberculosis 15740 R-PFA-200711 https://reactome.org/PathwayBrowser/#/R-PFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Plasmodium falciparum 15740 R-PFA-5696839 https://reactome.org/PathwayBrowser/#/R-PFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Plasmodium falciparum 15740 R-PFA-6801456 https://reactome.org/PathwayBrowser/#/R-PFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Plasmodium falciparum 15740 R-RNO-1237119 https://reactome.org/PathwayBrowser/#/R-RNO-1237119 Acireductone is oxidized to MOB IEA Rattus norvegicus 15740 R-RNO-1474146 https://reactome.org/PathwayBrowser/#/R-RNO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Rattus norvegicus 15740 R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 15740 R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 15740 R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 15740 R-RNO-200711 https://reactome.org/PathwayBrowser/#/R-RNO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Rattus norvegicus 15740 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15740 R-RNO-444047 https://reactome.org/PathwayBrowser/#/R-RNO-444047 Receptor FFAR3 binds carboxylates IEA Rattus norvegicus 15740 R-RNO-444171 https://reactome.org/PathwayBrowser/#/R-RNO-444171 Receptor FFAR2 binds carboxylates IEA Rattus norvegicus 15740 R-RNO-5693724 https://reactome.org/PathwayBrowser/#/R-RNO-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Rattus norvegicus 15740 R-RNO-5696839 https://reactome.org/PathwayBrowser/#/R-RNO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Rattus norvegicus 15740 R-RNO-6801456 https://reactome.org/PathwayBrowser/#/R-RNO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Rattus norvegicus 15740 R-SCE-1237119 https://reactome.org/PathwayBrowser/#/R-SCE-1237119 Acireductone is oxidized to MOB IEA Saccharomyces cerevisiae 15740 R-SCE-1474146 https://reactome.org/PathwayBrowser/#/R-SCE-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Saccharomyces cerevisiae 15740 R-SCE-194678 https://reactome.org/PathwayBrowser/#/R-SCE-194678 CYP51A1 demethylates LNSOL IEA Saccharomyces cerevisiae 15740 R-SCE-200711 https://reactome.org/PathwayBrowser/#/R-SCE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Saccharomyces cerevisiae 15740 R-SCE-5693724 https://reactome.org/PathwayBrowser/#/R-SCE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Saccharomyces cerevisiae 15740 R-SCE-5696839 https://reactome.org/PathwayBrowser/#/R-SCE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Saccharomyces cerevisiae 15740 R-SCE-6801456 https://reactome.org/PathwayBrowser/#/R-SCE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Saccharomyces cerevisiae 15740 R-SPO-1237119 https://reactome.org/PathwayBrowser/#/R-SPO-1237119 Acireductone is oxidized to MOB IEA Schizosaccharomyces pombe 15740 R-SPO-1474146 https://reactome.org/PathwayBrowser/#/R-SPO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Schizosaccharomyces pombe 15740 R-SPO-194678 https://reactome.org/PathwayBrowser/#/R-SPO-194678 CYP51A1 demethylates LNSOL IEA Schizosaccharomyces pombe 15740 R-SPO-200711 https://reactome.org/PathwayBrowser/#/R-SPO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Schizosaccharomyces pombe 15740 R-SPO-5696839 https://reactome.org/PathwayBrowser/#/R-SPO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Schizosaccharomyces pombe 15740 R-SPO-6801456 https://reactome.org/PathwayBrowser/#/R-SPO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Schizosaccharomyces pombe 15740 R-SSC-1237119 https://reactome.org/PathwayBrowser/#/R-SSC-1237119 Acireductone is oxidized to MOB IEA Sus scrofa 15740 R-SSC-1474146 https://reactome.org/PathwayBrowser/#/R-SSC-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Sus scrofa 15740 R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 15740 R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 15740 R-SSC-194678 https://reactome.org/PathwayBrowser/#/R-SSC-194678 CYP51A1 demethylates LNSOL IEA Sus scrofa 15740 R-SSC-200711 https://reactome.org/PathwayBrowser/#/R-SSC-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Sus scrofa 15740 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15740 R-SSC-444047 https://reactome.org/PathwayBrowser/#/R-SSC-444047 Receptor FFAR3 binds carboxylates IEA Sus scrofa 15740 R-SSC-444171 https://reactome.org/PathwayBrowser/#/R-SSC-444171 Receptor FFAR2 binds carboxylates IEA Sus scrofa 15740 R-SSC-5693724 https://reactome.org/PathwayBrowser/#/R-SSC-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Sus scrofa 15740 R-SSC-5696839 https://reactome.org/PathwayBrowser/#/R-SSC-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Sus scrofa 15740 R-SSC-6801456 https://reactome.org/PathwayBrowser/#/R-SSC-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Sus scrofa 15740 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15740 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15740 R-XTR-1237119 https://reactome.org/PathwayBrowser/#/R-XTR-1237119 Acireductone is oxidized to MOB IEA Xenopus tropicalis 15740 R-XTR-1474146 https://reactome.org/PathwayBrowser/#/R-XTR-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Xenopus tropicalis 15740 R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 15740 R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 15740 R-XTR-200711 https://reactome.org/PathwayBrowser/#/R-XTR-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Xenopus tropicalis 15740 R-XTR-444171 https://reactome.org/PathwayBrowser/#/R-XTR-444171 Receptor FFAR2 binds carboxylates IEA Xenopus tropicalis 15740 R-XTR-5693724 https://reactome.org/PathwayBrowser/#/R-XTR-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Xenopus tropicalis 15740 R-XTR-5696839 https://reactome.org/PathwayBrowser/#/R-XTR-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Xenopus tropicalis 15740 R-XTR-6801456 https://reactome.org/PathwayBrowser/#/R-XTR-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Xenopus tropicalis 15740 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 15740 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15748 R-BTA-5661256 https://reactome.org/PathwayBrowser/#/R-BTA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Bos taurus 15748 R-BTA-5678327 https://reactome.org/PathwayBrowser/#/R-BTA-5678327 MIOX oxidises Ins to GlcA IEA Bos taurus 15748 R-BTA-5694563 https://reactome.org/PathwayBrowser/#/R-BTA-5694563 ABHD10 hydrolyses MPAG IEA Bos taurus 15748 R-BTA-9756134 https://reactome.org/PathwayBrowser/#/R-BTA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Bos taurus 15748 R-BTA-9756156 https://reactome.org/PathwayBrowser/#/R-BTA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Bos taurus 15748 R-BTA-9756183 https://reactome.org/PathwayBrowser/#/R-BTA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Bos taurus 15748 R-CEL-5661256 https://reactome.org/PathwayBrowser/#/R-CEL-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Caenorhabditis elegans 15748 R-CEL-5678327 https://reactome.org/PathwayBrowser/#/R-CEL-5678327 MIOX oxidises Ins to GlcA IEA Caenorhabditis elegans 15748 R-CFA-5661256 https://reactome.org/PathwayBrowser/#/R-CFA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Canis familiaris 15748 R-CFA-5678327 https://reactome.org/PathwayBrowser/#/R-CFA-5678327 MIOX oxidises Ins to GlcA IEA Canis familiaris 15748 R-CFA-5694563 https://reactome.org/PathwayBrowser/#/R-CFA-5694563 ABHD10 hydrolyses MPAG IEA Canis familiaris 15748 R-DDI-5661256 https://reactome.org/PathwayBrowser/#/R-DDI-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Dictyostelium discoideum 15748 R-DDI-5678327 https://reactome.org/PathwayBrowser/#/R-DDI-5678327 MIOX oxidises Ins to GlcA IEA Dictyostelium discoideum 15748 R-DDI-9756134 https://reactome.org/PathwayBrowser/#/R-DDI-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Dictyostelium discoideum 15748 R-DDI-9756156 https://reactome.org/PathwayBrowser/#/R-DDI-9756156 UGT1A3 lactonizes ATV to ATVL IEA Dictyostelium discoideum 15748 R-DDI-9756183 https://reactome.org/PathwayBrowser/#/R-DDI-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Dictyostelium discoideum 15748 R-DME-5661256 https://reactome.org/PathwayBrowser/#/R-DME-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Drosophila melanogaster 15748 R-DME-5678327 https://reactome.org/PathwayBrowser/#/R-DME-5678327 MIOX oxidises Ins to GlcA IEA Drosophila melanogaster 15748 R-DRE-5661256 https://reactome.org/PathwayBrowser/#/R-DRE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Danio rerio 15748 R-DRE-5678327 https://reactome.org/PathwayBrowser/#/R-DRE-5678327 MIOX oxidises Ins to GlcA IEA Danio rerio 15748 R-GGA-5661256 https://reactome.org/PathwayBrowser/#/R-GGA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Gallus gallus 15748 R-GGA-5678327 https://reactome.org/PathwayBrowser/#/R-GGA-5678327 MIOX oxidises Ins to GlcA IEA Gallus gallus 15748 R-GGA-5694563 https://reactome.org/PathwayBrowser/#/R-GGA-5694563 ABHD10 hydrolyses MPAG IEA Gallus gallus 15748 R-GGA-9756134 https://reactome.org/PathwayBrowser/#/R-GGA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Gallus gallus 15748 R-GGA-9756156 https://reactome.org/PathwayBrowser/#/R-GGA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Gallus gallus 15748 R-GGA-9756183 https://reactome.org/PathwayBrowser/#/R-GGA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Gallus gallus 15748 R-HSA-2162229 https://reactome.org/PathwayBrowser/#/R-HSA-2162229 The single sugars GlcA and GlcNAc translocate from the lysosome to the cytosol TAS Homo sapiens 15748 R-HSA-5661256 https://reactome.org/PathwayBrowser/#/R-HSA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate TAS Homo sapiens 15748 R-HSA-5678327 https://reactome.org/PathwayBrowser/#/R-HSA-5678327 MIOX oxidises Ins to GlcA TAS Homo sapiens 15748 R-HSA-5694563 https://reactome.org/PathwayBrowser/#/R-HSA-5694563 ABHD10 hydrolyses MPAG TAS Homo sapiens 15748 R-HSA-6785668 https://reactome.org/PathwayBrowser/#/R-HSA-6785668 Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA TAS Homo sapiens 15748 R-HSA-9661820 https://reactome.org/PathwayBrowser/#/R-HSA-9661820 Bacterial GUSB hydrolyses BDG to BIL TAS Homo sapiens 15748 R-HSA-9756134 https://reactome.org/PathwayBrowser/#/R-HSA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL TAS Homo sapiens 15748 R-HSA-9756156 https://reactome.org/PathwayBrowser/#/R-HSA-9756156 UGT1A3 lactonizes ATV to ATVL TAS Homo sapiens 15748 R-HSA-9756183 https://reactome.org/PathwayBrowser/#/R-HSA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL TAS Homo sapiens 15748 R-MMU-5661256 https://reactome.org/PathwayBrowser/#/R-MMU-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Mus musculus 15748 R-MMU-5678327 https://reactome.org/PathwayBrowser/#/R-MMU-5678327 MIOX oxidises Ins to GlcA IEA Mus musculus 15748 R-MMU-5694563 https://reactome.org/PathwayBrowser/#/R-MMU-5694563 ABHD10 hydrolyses MPAG IEA Mus musculus 15748 R-MMU-9756134 https://reactome.org/PathwayBrowser/#/R-MMU-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Mus musculus 15748 R-MMU-9756156 https://reactome.org/PathwayBrowser/#/R-MMU-9756156 UGT1A3 lactonizes ATV to ATVL IEA Mus musculus 15748 R-MMU-9756183 https://reactome.org/PathwayBrowser/#/R-MMU-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Mus musculus 15748 R-RNO-5661256 https://reactome.org/PathwayBrowser/#/R-RNO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Rattus norvegicus 15748 R-RNO-5678327 https://reactome.org/PathwayBrowser/#/R-RNO-5678327 MIOX oxidises Ins to GlcA IEA Rattus norvegicus 15748 R-RNO-5694563 https://reactome.org/PathwayBrowser/#/R-RNO-5694563 ABHD10 hydrolyses MPAG IEA Rattus norvegicus 15748 R-RNO-9756134 https://reactome.org/PathwayBrowser/#/R-RNO-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Rattus norvegicus 15748 R-RNO-9756156 https://reactome.org/PathwayBrowser/#/R-RNO-9756156 UGT1A3 lactonizes ATV to ATVL IEA Rattus norvegicus 15748 R-RNO-9756183 https://reactome.org/PathwayBrowser/#/R-RNO-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Rattus norvegicus 15748 R-SCE-5661256 https://reactome.org/PathwayBrowser/#/R-SCE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Saccharomyces cerevisiae 15748 R-SPO-5661256 https://reactome.org/PathwayBrowser/#/R-SPO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Schizosaccharomyces pombe 15748 R-SSC-5661256 https://reactome.org/PathwayBrowser/#/R-SSC-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Sus scrofa 15748 R-SSC-5678327 https://reactome.org/PathwayBrowser/#/R-SSC-5678327 MIOX oxidises Ins to GlcA IEA Sus scrofa 15748 R-SSC-5694563 https://reactome.org/PathwayBrowser/#/R-SSC-5694563 ABHD10 hydrolyses MPAG IEA Sus scrofa 15748 R-SSC-9756134 https://reactome.org/PathwayBrowser/#/R-SSC-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Sus scrofa 15748 R-SSC-9756156 https://reactome.org/PathwayBrowser/#/R-SSC-9756156 UGT1A3 lactonizes ATV to ATVL IEA Sus scrofa 15748 R-SSC-9756183 https://reactome.org/PathwayBrowser/#/R-SSC-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Sus scrofa 15748 R-XTR-5661256 https://reactome.org/PathwayBrowser/#/R-XTR-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Xenopus tropicalis 15748 R-XTR-5694563 https://reactome.org/PathwayBrowser/#/R-XTR-5694563 ABHD10 hydrolyses MPAG IEA Xenopus tropicalis 15750 R-BTA-446200 https://reactome.org/PathwayBrowser/#/R-BTA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Bos taurus 15750 R-CFA-446200 https://reactome.org/PathwayBrowser/#/R-CFA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Canis familiaris 15750 R-DDI-446200 https://reactome.org/PathwayBrowser/#/R-DDI-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Dictyostelium discoideum 15750 R-DRE-446200 https://reactome.org/PathwayBrowser/#/R-DRE-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Danio rerio 15750 R-GGA-446200 https://reactome.org/PathwayBrowser/#/R-GGA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Gallus gallus 15750 R-HSA-446200 https://reactome.org/PathwayBrowser/#/R-HSA-446200 DOLPP1 dephosphorylates DOLDP to DOLP TAS Homo sapiens 15750 R-HSA-4717406 https://reactome.org/PathwayBrowser/#/R-HSA-4717406 Defective DPM1 does not transfer mannose to DOLP to form DOLPman TAS Homo sapiens 15750 R-HSA-4719354 https://reactome.org/PathwayBrowser/#/R-HSA-4719354 Defective DPM3 does not transfer mannose to DOLP to form DOLPman TAS Homo sapiens 15750 R-HSA-4719375 https://reactome.org/PathwayBrowser/#/R-HSA-4719375 Defective DPM2 does not transfer mannose to DOLP to form DOLPman TAS Homo sapiens 15750 R-MMU-446200 https://reactome.org/PathwayBrowser/#/R-MMU-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Mus musculus 15750 R-RNO-446200 https://reactome.org/PathwayBrowser/#/R-RNO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Rattus norvegicus 15750 R-SPO-446200 https://reactome.org/PathwayBrowser/#/R-SPO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Schizosaccharomyces pombe 15750 R-SSC-446200 https://reactome.org/PathwayBrowser/#/R-SSC-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Sus scrofa 15750 R-XTR-446200 https://reactome.org/PathwayBrowser/#/R-XTR-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Xenopus tropicalis 15756 R-BTA-201035 https://reactome.org/PathwayBrowser/#/R-BTA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Bos taurus 15756 R-BTA-203613 https://reactome.org/PathwayBrowser/#/R-BTA-203613 depalmitoylation of eNOS IEA Bos taurus 15756 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 15756 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15756 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 15756 R-BTA-390427 https://reactome.org/PathwayBrowser/#/R-BTA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Bos taurus 15756 R-BTA-400143 https://reactome.org/PathwayBrowser/#/R-BTA-400143 Fatty acid ligands activate PPARA IEA Bos taurus 15756 R-BTA-400434 https://reactome.org/PathwayBrowser/#/R-BTA-400434 FFAR1 binds fatty acids IEA Bos taurus 15756 R-BTA-400509 https://reactome.org/PathwayBrowser/#/R-BTA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Bos taurus 15756 R-BTA-416530 https://reactome.org/PathwayBrowser/#/R-BTA-416530 FFAR1:FFAR1 ligands activate Gq IEA Bos taurus 15756 R-BTA-434381 https://reactome.org/PathwayBrowser/#/R-BTA-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol IEA Bos taurus 15756 R-BTA-434382 https://reactome.org/PathwayBrowser/#/R-BTA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Bos taurus 15756 R-BTA-444202 https://reactome.org/PathwayBrowser/#/R-BTA-444202 Receptor FFAR1 binds free fatty acids IEA Bos taurus 15756 R-BTA-5690046 https://reactome.org/PathwayBrowser/#/R-BTA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Bos taurus 15756 R-BTA-5690517 https://reactome.org/PathwayBrowser/#/R-BTA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Bos taurus 15756 R-BTA-5692261 https://reactome.org/PathwayBrowser/#/R-BTA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Bos taurus 15756 R-BTA-5696080 https://reactome.org/PathwayBrowser/#/R-BTA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Bos taurus 15756 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 15756 R-BTA-6808464 https://reactome.org/PathwayBrowser/#/R-BTA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Bos taurus 15756 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15756 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15756 R-BTA-75872 https://reactome.org/PathwayBrowser/#/R-BTA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Bos taurus 15756 R-BTA-879585 https://reactome.org/PathwayBrowser/#/R-BTA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Bos taurus 15756 R-BTA-8933328 https://reactome.org/PathwayBrowser/#/R-BTA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Bos taurus 15756 R-BTA-975593 https://reactome.org/PathwayBrowser/#/R-BTA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Bos taurus 15756 R-BTA-975594 https://reactome.org/PathwayBrowser/#/R-BTA-975594 PLB1 hydrolyses RPALM to atROL IEA Bos taurus 15756 R-CEL-201035 https://reactome.org/PathwayBrowser/#/R-CEL-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Caenorhabditis elegans 15756 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 15756 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 15756 R-CEL-390427 https://reactome.org/PathwayBrowser/#/R-CEL-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Caenorhabditis elegans 15756 R-CEL-434381 https://reactome.org/PathwayBrowser/#/R-CEL-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol IEA Caenorhabditis elegans 15756 R-CEL-434382 https://reactome.org/PathwayBrowser/#/R-CEL-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Caenorhabditis elegans 15756 R-CEL-5690517 https://reactome.org/PathwayBrowser/#/R-CEL-5690517 PPT1 hydrolyses palmitoylated proteins IEA Caenorhabditis elegans 15756 R-CEL-5692261 https://reactome.org/PathwayBrowser/#/R-CEL-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Caenorhabditis elegans 15756 R-CEL-5696080 https://reactome.org/PathwayBrowser/#/R-CEL-5696080 ALDH3B1 oxidises HXAL to PALM IEA Caenorhabditis elegans 15756 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 15756 R-CEL-6808464 https://reactome.org/PathwayBrowser/#/R-CEL-6808464 ALDH3B2 oxidises HXAL to PALM IEA Caenorhabditis elegans 15756 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 15756 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15756 R-CEL-75872 https://reactome.org/PathwayBrowser/#/R-CEL-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Caenorhabditis elegans 15756 R-CEL-879585 https://reactome.org/PathwayBrowser/#/R-CEL-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Caenorhabditis elegans 15756 R-CEL-975594 https://reactome.org/PathwayBrowser/#/R-CEL-975594 PLB1 hydrolyses RPALM to atROL IEA Caenorhabditis elegans 15756 R-CFA-201035 https://reactome.org/PathwayBrowser/#/R-CFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Canis familiaris 15756 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 15756 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15756 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 15756 R-CFA-390427 https://reactome.org/PathwayBrowser/#/R-CFA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Canis familiaris 15756 R-CFA-400143 https://reactome.org/PathwayBrowser/#/R-CFA-400143 Fatty acid ligands activate PPARA IEA Canis familiaris 15756 R-CFA-400434 https://reactome.org/PathwayBrowser/#/R-CFA-400434 FFAR1 binds fatty acids IEA Canis familiaris 15756 R-CFA-400509 https://reactome.org/PathwayBrowser/#/R-CFA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Canis familiaris 15756 R-CFA-416530 https://reactome.org/PathwayBrowser/#/R-CFA-416530 FFAR1:FFAR1 ligands activate Gq IEA Canis familiaris 15756 R-CFA-434381 https://reactome.org/PathwayBrowser/#/R-CFA-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol IEA Canis familiaris 15756 R-CFA-434382 https://reactome.org/PathwayBrowser/#/R-CFA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Canis familiaris 15756 R-CFA-444202 https://reactome.org/PathwayBrowser/#/R-CFA-444202 Receptor FFAR1 binds free fatty acids IEA Canis familiaris 15756 R-CFA-5690046 https://reactome.org/PathwayBrowser/#/R-CFA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Canis familiaris 15756 R-CFA-5690517 https://reactome.org/PathwayBrowser/#/R-CFA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Canis familiaris 15756 R-CFA-5692261 https://reactome.org/PathwayBrowser/#/R-CFA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Canis familiaris 15756 R-CFA-5696080 https://reactome.org/PathwayBrowser/#/R-CFA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Canis familiaris 15756 R-CFA-6808464 https://reactome.org/PathwayBrowser/#/R-CFA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Canis familiaris 15756 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15756 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15756 R-CFA-75872 https://reactome.org/PathwayBrowser/#/R-CFA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Canis familiaris 15756 R-CFA-879585 https://reactome.org/PathwayBrowser/#/R-CFA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Canis familiaris 15756 R-CFA-8933328 https://reactome.org/PathwayBrowser/#/R-CFA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Canis familiaris 15756 R-CFA-975594 https://reactome.org/PathwayBrowser/#/R-CFA-975594 PLB1 hydrolyses RPALM to atROL IEA Canis familiaris 15756 R-DDI-201035 https://reactome.org/PathwayBrowser/#/R-DDI-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Dictyostelium discoideum 15756 R-DDI-203613 https://reactome.org/PathwayBrowser/#/R-DDI-203613 depalmitoylation of eNOS IEA Dictyostelium discoideum 15756 R-DDI-434381 https://reactome.org/PathwayBrowser/#/R-DDI-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol IEA Dictyostelium discoideum 15756 R-DDI-5690046 https://reactome.org/PathwayBrowser/#/R-DDI-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Dictyostelium discoideum 15756 R-DDI-5690517 https://reactome.org/PathwayBrowser/#/R-DDI-5690517 PPT1 hydrolyses palmitoylated proteins IEA Dictyostelium discoideum 15756 R-DDI-5692261 https://reactome.org/PathwayBrowser/#/R-DDI-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Dictyostelium discoideum 15756 R-DDI-5696080 https://reactome.org/PathwayBrowser/#/R-DDI-5696080 ALDH3B1 oxidises HXAL to PALM IEA Dictyostelium discoideum 15756 R-DDI-6808464 https://reactome.org/PathwayBrowser/#/R-DDI-6808464 ALDH3B2 oxidises HXAL to PALM IEA Dictyostelium discoideum 15756 R-DDI-75872 https://reactome.org/PathwayBrowser/#/R-DDI-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Dictyostelium discoideum 15756 R-DME-201035 https://reactome.org/PathwayBrowser/#/R-DME-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Drosophila melanogaster 15756 R-DME-203613 https://reactome.org/PathwayBrowser/#/R-DME-203613 depalmitoylation of eNOS IEA Drosophila melanogaster 15756 R-DME-209357 https://reactome.org/PathwayBrowser/#/R-DME-209357 N-HH is palmitoylated by RASP TAS Drosophila melanogaster 15756 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 15756 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 15756 R-DME-390427 https://reactome.org/PathwayBrowser/#/R-DME-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Drosophila melanogaster 15756 R-DME-400143 https://reactome.org/PathwayBrowser/#/R-DME-400143 Fatty acid ligands activate PPARA IEA Drosophila melanogaster 15756 R-DME-434381 https://reactome.org/PathwayBrowser/#/R-DME-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol IEA Drosophila melanogaster 15756 R-DME-434382 https://reactome.org/PathwayBrowser/#/R-DME-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Drosophila melanogaster 15756 R-DME-5690046 https://reactome.org/PathwayBrowser/#/R-DME-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Drosophila melanogaster 15756 R-DME-5690517 https://reactome.org/PathwayBrowser/#/R-DME-5690517 PPT1 hydrolyses palmitoylated proteins IEA Drosophila melanogaster 15756 R-DME-5692261 https://reactome.org/PathwayBrowser/#/R-DME-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Drosophila melanogaster 15756 R-DME-5696080 https://reactome.org/PathwayBrowser/#/R-DME-5696080 ALDH3B1 oxidises HXAL to PALM IEA Drosophila melanogaster 15756 R-DME-6808464 https://reactome.org/PathwayBrowser/#/R-DME-6808464 ALDH3B2 oxidises HXAL to PALM IEA Drosophila melanogaster 15756 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 15756 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15756 R-DME-75872 https://reactome.org/PathwayBrowser/#/R-DME-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Drosophila melanogaster 15756 R-DME-879585 https://reactome.org/PathwayBrowser/#/R-DME-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Drosophila melanogaster 15756 R-DME-975594 https://reactome.org/PathwayBrowser/#/R-DME-975594 PLB1 hydrolyses RPALM to atROL IEA Drosophila melanogaster 15756 R-DRE-201035 https://reactome.org/PathwayBrowser/#/R-DRE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Danio rerio 15756 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 15756 R-DRE-400143 https://reactome.org/PathwayBrowser/#/R-DRE-400143 Fatty acid ligands activate PPARA IEA Danio rerio 15756 R-DRE-434381 https://reactome.org/PathwayBrowser/#/R-DRE-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol IEA Danio rerio 15756 R-DRE-434382 https://reactome.org/PathwayBrowser/#/R-DRE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Danio rerio 15756 R-DRE-5690046 https://reactome.org/PathwayBrowser/#/R-DRE-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Danio rerio 15756 R-DRE-5690517 https://reactome.org/PathwayBrowser/#/R-DRE-5690517 PPT1 hydrolyses palmitoylated proteins IEA Danio rerio 15756 R-DRE-5692261 https://reactome.org/PathwayBrowser/#/R-DRE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Danio rerio 15756 R-DRE-5696080 https://reactome.org/PathwayBrowser/#/R-DRE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Danio rerio 15756 R-DRE-6808464 https://reactome.org/PathwayBrowser/#/R-DRE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Danio rerio 15756 R-DRE-75872 https://reactome.org/PathwayBrowser/#/R-DRE-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Danio rerio 15756 R-DRE-879585 https://reactome.org/PathwayBrowser/#/R-DRE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Danio rerio 15756 R-DRE-8933328 https://reactome.org/PathwayBrowser/#/R-DRE-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Danio rerio 15756 R-GGA-201035 https://reactome.org/PathwayBrowser/#/R-GGA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Gallus gallus 15756 R-GGA-203613 https://reactome.org/PathwayBrowser/#/R-GGA-203613 depalmitoylation of eNOS IEA Gallus gallus 15756 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 15756 R-GGA-2465974 https://reactome.org/PathwayBrowser/#/R-GGA-2465974 An REH hydrolyses 11cRE to 11cROL TAS Gallus gallus 15756 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 15756 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 15756 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus 15756 R-GGA-434381 https://reactome.org/PathwayBrowser/#/R-GGA-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol IEA Gallus gallus 15756 R-GGA-434382 https://reactome.org/PathwayBrowser/#/R-GGA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Gallus gallus 15756 R-GGA-5690517 https://reactome.org/PathwayBrowser/#/R-GGA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Gallus gallus 15756 R-GGA-5692261 https://reactome.org/PathwayBrowser/#/R-GGA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Gallus gallus 15756 R-GGA-5696080 https://reactome.org/PathwayBrowser/#/R-GGA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Gallus gallus 15756 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 15756 R-GGA-6808464 https://reactome.org/PathwayBrowser/#/R-GGA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Gallus gallus 15756 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 15756 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15756 R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Gallus gallus 15756 R-GGA-879585 https://reactome.org/PathwayBrowser/#/R-GGA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Gallus gallus 15756 R-GGA-8933328 https://reactome.org/PathwayBrowser/#/R-GGA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Gallus gallus 15756 R-GGA-975593 https://reactome.org/PathwayBrowser/#/R-GGA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Gallus gallus 15756 R-GGA-975594 https://reactome.org/PathwayBrowser/#/R-GGA-975594 PLB1 hydrolyses RPALM to atROL IEA Gallus gallus 15756 R-HSA-1368065 https://reactome.org/PathwayBrowser/#/R-HSA-1368065 Expression of NPAS2 IEA Homo sapiens 15756 R-HSA-1592238 https://reactome.org/PathwayBrowser/#/R-HSA-1592238 Expression of ALAS1 TAS Homo sapiens 15756 R-HSA-1655826 https://reactome.org/PathwayBrowser/#/R-HSA-1655826 Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) TAS Homo sapiens 15756 R-HSA-1655848 https://reactome.org/PathwayBrowser/#/R-HSA-1655848 Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) TAS Homo sapiens 15756 R-HSA-1655850 https://reactome.org/PathwayBrowser/#/R-HSA-1655850 Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) TAS Homo sapiens 15756 R-HSA-1801587 https://reactome.org/PathwayBrowser/#/R-HSA-1801587 Expression of CPT1A IEA Homo sapiens 15756 R-HSA-1989745 https://reactome.org/PathwayBrowser/#/R-HSA-1989745 Expression of ACADM TAS Homo sapiens 15756 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 15756 R-HSA-1989747 https://reactome.org/PathwayBrowser/#/R-HSA-1989747 Expression of FHL2 TAS Homo sapiens 15756 R-HSA-1989748 https://reactome.org/PathwayBrowser/#/R-HSA-1989748 Expression of GRHL1 TAS Homo sapiens 15756 R-HSA-1989749 https://reactome.org/PathwayBrowser/#/R-HSA-1989749 Expression of ACOX1 TAS Homo sapiens 15756 R-HSA-1989750 https://reactome.org/PathwayBrowser/#/R-HSA-1989750 Expression of FATP1 (SLC27A1) TAS Homo sapiens 15756 R-HSA-1989751 https://reactome.org/PathwayBrowser/#/R-HSA-1989751 Expression of FABP1 TAS Homo sapiens 15756 R-HSA-1989752 https://reactome.org/PathwayBrowser/#/R-HSA-1989752 Expression of TXNRD1 TAS Homo sapiens 15756 R-HSA-1989753 https://reactome.org/PathwayBrowser/#/R-HSA-1989753 Expression of PEX11A TAS Homo sapiens 15756 R-HSA-1989754 https://reactome.org/PathwayBrowser/#/R-HSA-1989754 Expression of APOA1 TAS Homo sapiens 15756 R-HSA-1989755 https://reactome.org/PathwayBrowser/#/R-HSA-1989755 Expression of CYP4A11 TAS Homo sapiens 15756 R-HSA-1989756 https://reactome.org/PathwayBrowser/#/R-HSA-1989756 Expression of ME1 TAS Homo sapiens 15756 R-HSA-1989757 https://reactome.org/PathwayBrowser/#/R-HSA-1989757 Expression of FADS1 TAS Homo sapiens 15756 R-HSA-1989758 https://reactome.org/PathwayBrowser/#/R-HSA-1989758 Expression of UGT1A9 TAS Homo sapiens 15756 R-HSA-1989759 https://reactome.org/PathwayBrowser/#/R-HSA-1989759 Expression of G0S2 TAS Homo sapiens 15756 R-HSA-1989760 https://reactome.org/PathwayBrowser/#/R-HSA-1989760 Expression of HMGCS2 TAS Homo sapiens 15756 R-HSA-1989761 https://reactome.org/PathwayBrowser/#/R-HSA-1989761 Expression of APOA5 TAS Homo sapiens 15756 R-HSA-1989762 https://reactome.org/PathwayBrowser/#/R-HSA-1989762 Expression of ABCB4 TAS Homo sapiens 15756 R-HSA-1989764 https://reactome.org/PathwayBrowser/#/R-HSA-1989764 Expression of CYP1A1 TAS Homo sapiens 15756 R-HSA-1989765 https://reactome.org/PathwayBrowser/#/R-HSA-1989765 Expression of ABCA1 TAS Homo sapiens 15756 R-HSA-1989767 https://reactome.org/PathwayBrowser/#/R-HSA-1989767 Expression of TRIB3 TAS Homo sapiens 15756 R-HSA-1989768 https://reactome.org/PathwayBrowser/#/R-HSA-1989768 Expression of TIAM2 TAS Homo sapiens 15756 R-HSA-1989770 https://reactome.org/PathwayBrowser/#/R-HSA-1989770 Expression of PLIN2 TAS Homo sapiens 15756 R-HSA-1989771 https://reactome.org/PathwayBrowser/#/R-HSA-1989771 Expression of TNFRSF21 TAS Homo sapiens 15756 R-HSA-1989772 https://reactome.org/PathwayBrowser/#/R-HSA-1989772 Expression of GLIPR1 TAS Homo sapiens 15756 R-HSA-1989773 https://reactome.org/PathwayBrowser/#/R-HSA-1989773 Expression of CPT2 TAS Homo sapiens 15756 R-HSA-1989774 https://reactome.org/PathwayBrowser/#/R-HSA-1989774 Expression of AGT TAS Homo sapiens 15756 R-HSA-1989775 https://reactome.org/PathwayBrowser/#/R-HSA-1989775 Expression of SULT2A1 TAS Homo sapiens 15756 R-HSA-1989776 https://reactome.org/PathwayBrowser/#/R-HSA-1989776 Expression of APOA2 TAS Homo sapiens 15756 R-HSA-1989777 https://reactome.org/PathwayBrowser/#/R-HSA-1989777 Expression of RGL1 TAS Homo sapiens 15756 R-HSA-1989778 https://reactome.org/PathwayBrowser/#/R-HSA-1989778 Expression of ACSL1 TAS Homo sapiens 15756 R-HSA-1989779 https://reactome.org/PathwayBrowser/#/R-HSA-1989779 Expression of ANKRD1 TAS Homo sapiens 15756 R-HSA-201035 https://reactome.org/PathwayBrowser/#/R-HSA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA TAS Homo sapiens 15756 R-HSA-203613 https://reactome.org/PathwayBrowser/#/R-HSA-203613 depalmitoylation of eNOS TAS Homo sapiens 15756 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 15756 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 15756 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 15756 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 15756 R-HSA-2465941 https://reactome.org/PathwayBrowser/#/R-HSA-2465941 A REH hydrolyses 11cRE to 11cROL IEA Homo sapiens 15756 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15756 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 15756 R-HSA-390427 https://reactome.org/PathwayBrowser/#/R-HSA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate TAS Homo sapiens 15756 R-HSA-400143 https://reactome.org/PathwayBrowser/#/R-HSA-400143 Fatty acid ligands activate PPARA TAS Homo sapiens 15756 R-HSA-400434 https://reactome.org/PathwayBrowser/#/R-HSA-400434 FFAR1 binds fatty acids TAS Homo sapiens 15756 R-HSA-400509 https://reactome.org/PathwayBrowser/#/R-HSA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells TAS Homo sapiens 15756 R-HSA-416530 https://reactome.org/PathwayBrowser/#/R-HSA-416530 FFAR1:FFAR1 ligands activate Gq TAS Homo sapiens 15756 R-HSA-434381 https://reactome.org/PathwayBrowser/#/R-HSA-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol TAS Homo sapiens 15756 R-HSA-434382 https://reactome.org/PathwayBrowser/#/R-HSA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell TAS Homo sapiens 15756 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 15756 R-HSA-444202 https://reactome.org/PathwayBrowser/#/R-HSA-444202 Receptor FFAR1 binds free fatty acids TAS Homo sapiens 15756 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 15756 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 15756 R-HSA-5627891 https://reactome.org/PathwayBrowser/#/R-HSA-5627891 Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol TAS Homo sapiens 15756 R-HSA-5690046 https://reactome.org/PathwayBrowser/#/R-HSA-5690046 PPT2 hydrolyses PALMCoA to PALM TAS Homo sapiens 15756 R-HSA-5690517 https://reactome.org/PathwayBrowser/#/R-HSA-5690517 PPT1 hydrolyses palmitoylated proteins TAS Homo sapiens 15756 R-HSA-5692261 https://reactome.org/PathwayBrowser/#/R-HSA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM TAS Homo sapiens 15756 R-HSA-5696080 https://reactome.org/PathwayBrowser/#/R-HSA-5696080 ALDH3B1 oxidises HXAL to PALM TAS Homo sapiens 15756 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 15756 R-HSA-6808464 https://reactome.org/PathwayBrowser/#/R-HSA-6808464 ALDH3B2 oxidises HXAL to PALM TAS Homo sapiens 15756 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15756 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15756 R-HSA-75872 https://reactome.org/PathwayBrowser/#/R-HSA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O TAS Homo sapiens 15756 R-HSA-879585 https://reactome.org/PathwayBrowser/#/R-HSA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol TAS Homo sapiens 15756 R-HSA-879724 https://reactome.org/PathwayBrowser/#/R-HSA-879724 Expression of PPARA IEA Homo sapiens 15756 R-HSA-8933328 https://reactome.org/PathwayBrowser/#/R-HSA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 TAS Homo sapiens 15756 R-HSA-975593 https://reactome.org/PathwayBrowser/#/R-HSA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM TAS Homo sapiens 15756 R-HSA-975594 https://reactome.org/PathwayBrowser/#/R-HSA-975594 PLB1 hydrolyses RPALM to atROL TAS Homo sapiens 15756 R-MMU-201035 https://reactome.org/PathwayBrowser/#/R-MMU-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Mus musculus 15756 R-MMU-203613 https://reactome.org/PathwayBrowser/#/R-MMU-203613 depalmitoylation of eNOS IEA Mus musculus 15756 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 15756 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15756 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 15756 R-MMU-390427 https://reactome.org/PathwayBrowser/#/R-MMU-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Mus musculus 15756 R-MMU-400143 https://reactome.org/PathwayBrowser/#/R-MMU-400143 Fatty acid ligands activate PPARA IEA Mus musculus 15756 R-MMU-400434 https://reactome.org/PathwayBrowser/#/R-MMU-400434 FFAR1 binds fatty acids IEA Mus musculus 15756 R-MMU-400509 https://reactome.org/PathwayBrowser/#/R-MMU-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Mus musculus 15756 R-MMU-416530 https://reactome.org/PathwayBrowser/#/R-MMU-416530 FFAR1:FFAR1 ligands activate Gq IEA Mus musculus 15756 R-MMU-434381 https://reactome.org/PathwayBrowser/#/R-MMU-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol IEA Mus musculus 15756 R-MMU-434382 https://reactome.org/PathwayBrowser/#/R-MMU-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Mus musculus 15756 R-MMU-444202 https://reactome.org/PathwayBrowser/#/R-MMU-444202 Receptor FFAR1 binds free fatty acids IEA Mus musculus 15756 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 15756 R-MMU-5690046 https://reactome.org/PathwayBrowser/#/R-MMU-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Mus musculus 15756 R-MMU-5690517 https://reactome.org/PathwayBrowser/#/R-MMU-5690517 PPT1 hydrolyses palmitoylated proteins IEA Mus musculus 15756 R-MMU-5692261 https://reactome.org/PathwayBrowser/#/R-MMU-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Mus musculus 15756 R-MMU-5696080 https://reactome.org/PathwayBrowser/#/R-MMU-5696080 ALDH3B1 oxidises HXAL to PALM IEA Mus musculus 15756 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 15756 R-MMU-6808464 https://reactome.org/PathwayBrowser/#/R-MMU-6808464 ALDH3B2 oxidises HXAL to PALM IEA Mus musculus 15756 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15756 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15756 R-MMU-75872 https://reactome.org/PathwayBrowser/#/R-MMU-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Mus musculus 15756 R-MMU-879585 https://reactome.org/PathwayBrowser/#/R-MMU-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Mus musculus 15756 R-MMU-8933328 https://reactome.org/PathwayBrowser/#/R-MMU-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Mus musculus 15756 R-MMU-975593 https://reactome.org/PathwayBrowser/#/R-MMU-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Mus musculus 15756 R-MMU-975594 https://reactome.org/PathwayBrowser/#/R-MMU-975594 PLB1 hydrolyses RPALM to atROL IEA Mus musculus 15756 R-PFA-201035 https://reactome.org/PathwayBrowser/#/R-PFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Plasmodium falciparum 15756 R-RNO-201035 https://reactome.org/PathwayBrowser/#/R-RNO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Rattus norvegicus 15756 R-RNO-203613 https://reactome.org/PathwayBrowser/#/R-RNO-203613 depalmitoylation of eNOS IEA Rattus norvegicus 15756 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 15756 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15756 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 15756 R-RNO-390427 https://reactome.org/PathwayBrowser/#/R-RNO-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Rattus norvegicus 15756 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus 15756 R-RNO-400434 https://reactome.org/PathwayBrowser/#/R-RNO-400434 FFAR1 binds fatty acids IEA Rattus norvegicus 15756 R-RNO-400509 https://reactome.org/PathwayBrowser/#/R-RNO-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Rattus norvegicus 15756 R-RNO-416530 https://reactome.org/PathwayBrowser/#/R-RNO-416530 FFAR1:FFAR1 ligands activate Gq IEA Rattus norvegicus 15756 R-RNO-434381 https://reactome.org/PathwayBrowser/#/R-RNO-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol IEA Rattus norvegicus 15756 R-RNO-434382 https://reactome.org/PathwayBrowser/#/R-RNO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Rattus norvegicus 15756 R-RNO-444202 https://reactome.org/PathwayBrowser/#/R-RNO-444202 Receptor FFAR1 binds free fatty acids IEA Rattus norvegicus 15756 R-RNO-5690046 https://reactome.org/PathwayBrowser/#/R-RNO-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Rattus norvegicus 15756 R-RNO-5690517 https://reactome.org/PathwayBrowser/#/R-RNO-5690517 PPT1 hydrolyses palmitoylated proteins IEA Rattus norvegicus 15756 R-RNO-5692261 https://reactome.org/PathwayBrowser/#/R-RNO-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Rattus norvegicus 15756 R-RNO-5696080 https://reactome.org/PathwayBrowser/#/R-RNO-5696080 ALDH3B1 oxidises HXAL to PALM IEA Rattus norvegicus 15756 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 15756 R-RNO-6808464 https://reactome.org/PathwayBrowser/#/R-RNO-6808464 ALDH3B2 oxidises HXAL to PALM IEA Rattus norvegicus 15756 R-RNO-75872 https://reactome.org/PathwayBrowser/#/R-RNO-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Rattus norvegicus 15756 R-RNO-879585 https://reactome.org/PathwayBrowser/#/R-RNO-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Rattus norvegicus 15756 R-RNO-8933328 https://reactome.org/PathwayBrowser/#/R-RNO-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Rattus norvegicus 15756 R-RNO-975593 https://reactome.org/PathwayBrowser/#/R-RNO-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Rattus norvegicus 15756 R-RNO-975594 https://reactome.org/PathwayBrowser/#/R-RNO-975594 PLB1 hydrolyses RPALM to atROL IEA Rattus norvegicus 15756 R-SCE-201035 https://reactome.org/PathwayBrowser/#/R-SCE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Saccharomyces cerevisiae 15756 R-SCE-203613 https://reactome.org/PathwayBrowser/#/R-SCE-203613 depalmitoylation of eNOS IEA Saccharomyces cerevisiae 15756 R-SCE-434382 https://reactome.org/PathwayBrowser/#/R-SCE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Saccharomyces cerevisiae 15756 R-SCE-5692261 https://reactome.org/PathwayBrowser/#/R-SCE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Saccharomyces cerevisiae 15756 R-SCE-5696080 https://reactome.org/PathwayBrowser/#/R-SCE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 15756 R-SCE-6808464 https://reactome.org/PathwayBrowser/#/R-SCE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 15756 R-SCE-879585 https://reactome.org/PathwayBrowser/#/R-SCE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Saccharomyces cerevisiae 15756 R-SPO-201035 https://reactome.org/PathwayBrowser/#/R-SPO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Schizosaccharomyces pombe 15756 R-SPO-203613 https://reactome.org/PathwayBrowser/#/R-SPO-203613 depalmitoylation of eNOS IEA Schizosaccharomyces pombe 15756 R-SPO-434382 https://reactome.org/PathwayBrowser/#/R-SPO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Schizosaccharomyces pombe 15756 R-SSC-201035 https://reactome.org/PathwayBrowser/#/R-SSC-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Sus scrofa 15756 R-SSC-203613 https://reactome.org/PathwayBrowser/#/R-SSC-203613 depalmitoylation of eNOS IEA Sus scrofa 15756 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 15756 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15756 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 15756 R-SSC-390427 https://reactome.org/PathwayBrowser/#/R-SSC-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Sus scrofa 15756 R-SSC-434381 https://reactome.org/PathwayBrowser/#/R-SSC-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol IEA Sus scrofa 15756 R-SSC-434382 https://reactome.org/PathwayBrowser/#/R-SSC-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Sus scrofa 15756 R-SSC-5690046 https://reactome.org/PathwayBrowser/#/R-SSC-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Sus scrofa 15756 R-SSC-5690517 https://reactome.org/PathwayBrowser/#/R-SSC-5690517 PPT1 hydrolyses palmitoylated proteins IEA Sus scrofa 15756 R-SSC-5692261 https://reactome.org/PathwayBrowser/#/R-SSC-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Sus scrofa 15756 R-SSC-5696080 https://reactome.org/PathwayBrowser/#/R-SSC-5696080 ALDH3B1 oxidises HXAL to PALM IEA Sus scrofa 15756 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 15756 R-SSC-6808464 https://reactome.org/PathwayBrowser/#/R-SSC-6808464 ALDH3B2 oxidises HXAL to PALM IEA Sus scrofa 15756 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15756 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15756 R-SSC-75872 https://reactome.org/PathwayBrowser/#/R-SSC-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Sus scrofa 15756 R-SSC-879585 https://reactome.org/PathwayBrowser/#/R-SSC-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Sus scrofa 15756 R-SSC-8933328 https://reactome.org/PathwayBrowser/#/R-SSC-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Sus scrofa 15756 R-SSC-975593 https://reactome.org/PathwayBrowser/#/R-SSC-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Sus scrofa 15756 R-SSC-975594 https://reactome.org/PathwayBrowser/#/R-SSC-975594 PLB1 hydrolyses RPALM to atROL IEA Sus scrofa 15756 R-XTR-201035 https://reactome.org/PathwayBrowser/#/R-XTR-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Xenopus tropicalis 15756 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 15756 R-XTR-390427 https://reactome.org/PathwayBrowser/#/R-XTR-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Xenopus tropicalis 15756 R-XTR-434381 https://reactome.org/PathwayBrowser/#/R-XTR-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol IEA Xenopus tropicalis 15756 R-XTR-434382 https://reactome.org/PathwayBrowser/#/R-XTR-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Xenopus tropicalis 15756 R-XTR-5690046 https://reactome.org/PathwayBrowser/#/R-XTR-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Xenopus tropicalis 15756 R-XTR-5690517 https://reactome.org/PathwayBrowser/#/R-XTR-5690517 PPT1 hydrolyses palmitoylated proteins IEA Xenopus tropicalis 15756 R-XTR-5696080 https://reactome.org/PathwayBrowser/#/R-XTR-5696080 ALDH3B1 oxidises HXAL to PALM IEA Xenopus tropicalis 15756 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 15756 R-XTR-6808464 https://reactome.org/PathwayBrowser/#/R-XTR-6808464 ALDH3B2 oxidises HXAL to PALM IEA Xenopus tropicalis 15756 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15756 R-XTR-75872 https://reactome.org/PathwayBrowser/#/R-XTR-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Xenopus tropicalis 15756 R-XTR-879585 https://reactome.org/PathwayBrowser/#/R-XTR-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Xenopus tropicalis 15756 R-XTR-975593 https://reactome.org/PathwayBrowser/#/R-XTR-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Xenopus tropicalis 15760 R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus 15760 R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 15760 R-CFA-141202 https://reactome.org/PathwayBrowser/#/R-CFA-141202 MAOB:FAD oxidatively deaminates TYR IEA Canis familiaris 15760 R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 15760 R-DDI-141202 https://reactome.org/PathwayBrowser/#/R-DDI-141202 MAOB:FAD oxidatively deaminates TYR IEA Dictyostelium discoideum 15760 R-DRE-141202 https://reactome.org/PathwayBrowser/#/R-DRE-141202 MAOB:FAD oxidatively deaminates TYR IEA Danio rerio 15760 R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus 15760 R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 15760 R-HSA-141202 https://reactome.org/PathwayBrowser/#/R-HSA-141202 MAOB:FAD oxidatively deaminates TYR TAS Homo sapiens 15760 R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 15760 R-MMU-141202 https://reactome.org/PathwayBrowser/#/R-MMU-141202 MAOB:FAD oxidatively deaminates TYR IEA Mus musculus 15760 R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 15760 R-RNO-141202 https://reactome.org/PathwayBrowser/#/R-RNO-141202 MAOB:FAD oxidatively deaminates TYR IEA Rattus norvegicus 15760 R-SSC-141202 https://reactome.org/PathwayBrowser/#/R-SSC-141202 MAOB:FAD oxidatively deaminates TYR IEA Sus scrofa 15760 R-SSC-5696146 https://reactome.org/PathwayBrowser/#/R-SSC-5696146 AOC2 deaminates TYR IEA Sus scrofa 15760 R-XTR-141202 https://reactome.org/PathwayBrowser/#/R-XTR-141202 MAOB:FAD oxidatively deaminates TYR IEA Xenopus tropicalis 15761 R-BTA-175987 https://reactome.org/PathwayBrowser/#/R-BTA-175987 NNMT transfers CH3 from AdoMet to PY IEA Bos taurus 15761 R-CEL-175987 https://reactome.org/PathwayBrowser/#/R-CEL-175987 NNMT transfers CH3 from AdoMet to PY IEA Caenorhabditis elegans 15761 R-CFA-175987 https://reactome.org/PathwayBrowser/#/R-CFA-175987 NNMT transfers CH3 from AdoMet to PY IEA Canis familiaris 15761 R-DRE-175987 https://reactome.org/PathwayBrowser/#/R-DRE-175987 NNMT transfers CH3 from AdoMet to PY IEA Danio rerio 15761 R-HSA-175987 https://reactome.org/PathwayBrowser/#/R-HSA-175987 NNMT transfers CH3 from AdoMet to PY TAS Homo sapiens 15761 R-MMU-175987 https://reactome.org/PathwayBrowser/#/R-MMU-175987 NNMT transfers CH3 from AdoMet to PY IEA Mus musculus 15761 R-RNO-175987 https://reactome.org/PathwayBrowser/#/R-RNO-175987 NNMT transfers CH3 from AdoMet to PY IEA Rattus norvegicus 15761 R-SSC-175987 https://reactome.org/PathwayBrowser/#/R-SSC-175987 NNMT transfers CH3 from AdoMet to PY IEA Sus scrofa 15761 R-XTR-175987 https://reactome.org/PathwayBrowser/#/R-XTR-175987 NNMT transfers CH3 from AdoMet to PY IEA Xenopus tropicalis 15763 R-BTA-197186 https://reactome.org/PathwayBrowser/#/R-BTA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Bos taurus 15763 R-BTA-197235 https://reactome.org/PathwayBrowser/#/R-BTA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 15763 R-BTA-197250 https://reactome.org/PathwayBrowser/#/R-BTA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Bos taurus 15763 R-BTA-197268 https://reactome.org/PathwayBrowser/#/R-BTA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Bos taurus 15763 R-BTA-200474 https://reactome.org/PathwayBrowser/#/R-BTA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 15763 R-BTA-200512 https://reactome.org/PathwayBrowser/#/R-BTA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 15763 R-BTA-8869606 https://reactome.org/PathwayBrowser/#/R-BTA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Bos taurus 15763 R-BTA-8869607 https://reactome.org/PathwayBrowser/#/R-BTA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Bos taurus 15763 R-CEL-197186 https://reactome.org/PathwayBrowser/#/R-CEL-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Caenorhabditis elegans 15763 R-CEL-197235 https://reactome.org/PathwayBrowser/#/R-CEL-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 15763 R-CEL-200474 https://reactome.org/PathwayBrowser/#/R-CEL-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 15763 R-CEL-200512 https://reactome.org/PathwayBrowser/#/R-CEL-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 15763 R-CFA-197186 https://reactome.org/PathwayBrowser/#/R-CFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Canis familiaris 15763 R-CFA-197235 https://reactome.org/PathwayBrowser/#/R-CFA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 15763 R-CFA-197250 https://reactome.org/PathwayBrowser/#/R-CFA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Canis familiaris 15763 R-CFA-197268 https://reactome.org/PathwayBrowser/#/R-CFA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Canis familiaris 15763 R-CFA-200474 https://reactome.org/PathwayBrowser/#/R-CFA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 15763 R-CFA-200512 https://reactome.org/PathwayBrowser/#/R-CFA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 15763 R-CFA-8869606 https://reactome.org/PathwayBrowser/#/R-CFA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Canis familiaris 15763 R-DDI-197186 https://reactome.org/PathwayBrowser/#/R-DDI-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Dictyostelium discoideum 15763 R-DDI-197235 https://reactome.org/PathwayBrowser/#/R-DDI-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 15763 R-DDI-197268 https://reactome.org/PathwayBrowser/#/R-DDI-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Dictyostelium discoideum 15763 R-DDI-200474 https://reactome.org/PathwayBrowser/#/R-DDI-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 15763 R-DDI-200512 https://reactome.org/PathwayBrowser/#/R-DDI-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 15763 R-DDI-8869606 https://reactome.org/PathwayBrowser/#/R-DDI-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 15763 R-DDI-8869607 https://reactome.org/PathwayBrowser/#/R-DDI-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 15763 R-DME-197186 https://reactome.org/PathwayBrowser/#/R-DME-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Drosophila melanogaster 15763 R-DME-197235 https://reactome.org/PathwayBrowser/#/R-DME-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 15763 R-DME-200474 https://reactome.org/PathwayBrowser/#/R-DME-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 15763 R-DME-200512 https://reactome.org/PathwayBrowser/#/R-DME-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 15763 R-DME-8869606 https://reactome.org/PathwayBrowser/#/R-DME-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 15763 R-DME-8869607 https://reactome.org/PathwayBrowser/#/R-DME-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 15763 R-DRE-197186 https://reactome.org/PathwayBrowser/#/R-DRE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Danio rerio 15763 R-DRE-197235 https://reactome.org/PathwayBrowser/#/R-DRE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 15763 R-DRE-200512 https://reactome.org/PathwayBrowser/#/R-DRE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 15763 R-DRE-8869607 https://reactome.org/PathwayBrowser/#/R-DRE-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Danio rerio 15763 R-GGA-197186 https://reactome.org/PathwayBrowser/#/R-GGA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Gallus gallus 15763 R-GGA-197235 https://reactome.org/PathwayBrowser/#/R-GGA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 15763 R-GGA-197250 https://reactome.org/PathwayBrowser/#/R-GGA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Gallus gallus 15763 R-GGA-197268 https://reactome.org/PathwayBrowser/#/R-GGA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Gallus gallus 15763 R-GGA-200474 https://reactome.org/PathwayBrowser/#/R-GGA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 15763 R-GGA-200512 https://reactome.org/PathwayBrowser/#/R-GGA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 15763 R-GGA-8869606 https://reactome.org/PathwayBrowser/#/R-GGA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Gallus gallus 15763 R-GGA-8869607 https://reactome.org/PathwayBrowser/#/R-GGA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Gallus gallus 15763 R-HSA-197186 https://reactome.org/PathwayBrowser/#/R-HSA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN TAS Homo sapiens 15763 R-HSA-197235 https://reactome.org/PathwayBrowser/#/R-HSA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 15763 R-HSA-197250 https://reactome.org/PathwayBrowser/#/R-HSA-197250 NAMPT transfers PRIB to NAM to form NAMN TAS Homo sapiens 15763 R-HSA-197268 https://reactome.org/PathwayBrowser/#/R-HSA-197268 QPRT transfers PRIB to QUIN to form NAMN TAS Homo sapiens 15763 R-HSA-200474 https://reactome.org/PathwayBrowser/#/R-HSA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 15763 R-HSA-200512 https://reactome.org/PathwayBrowser/#/R-HSA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 15763 R-HSA-8869606 https://reactome.org/PathwayBrowser/#/R-HSA-8869606 NMRK1 phosphorylates NAR to yield NAMN TAS Homo sapiens 15763 R-HSA-8869607 https://reactome.org/PathwayBrowser/#/R-HSA-8869607 NMRK2 phosphorylates NAR to yield NAMN TAS Homo sapiens 15763 R-MMU-197186 https://reactome.org/PathwayBrowser/#/R-MMU-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Mus musculus 15763 R-MMU-197235 https://reactome.org/PathwayBrowser/#/R-MMU-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 15763 R-MMU-197250 https://reactome.org/PathwayBrowser/#/R-MMU-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Mus musculus 15763 R-MMU-197268 https://reactome.org/PathwayBrowser/#/R-MMU-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Mus musculus 15763 R-MMU-200474 https://reactome.org/PathwayBrowser/#/R-MMU-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 15763 R-MMU-200512 https://reactome.org/PathwayBrowser/#/R-MMU-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 15763 R-MMU-8869606 https://reactome.org/PathwayBrowser/#/R-MMU-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Mus musculus 15763 R-MMU-8869607 https://reactome.org/PathwayBrowser/#/R-MMU-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Mus musculus 15763 R-PFA-197186 https://reactome.org/PathwayBrowser/#/R-PFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Plasmodium falciparum 15763 R-RNO-197186 https://reactome.org/PathwayBrowser/#/R-RNO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Rattus norvegicus 15763 R-RNO-197235 https://reactome.org/PathwayBrowser/#/R-RNO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 15763 R-RNO-197250 https://reactome.org/PathwayBrowser/#/R-RNO-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Rattus norvegicus 15763 R-RNO-197268 https://reactome.org/PathwayBrowser/#/R-RNO-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Rattus norvegicus 15763 R-RNO-200474 https://reactome.org/PathwayBrowser/#/R-RNO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 15763 R-RNO-200512 https://reactome.org/PathwayBrowser/#/R-RNO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 15763 R-RNO-8869606 https://reactome.org/PathwayBrowser/#/R-RNO-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Rattus norvegicus 15763 R-SCE-197186 https://reactome.org/PathwayBrowser/#/R-SCE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Saccharomyces cerevisiae 15763 R-SCE-197235 https://reactome.org/PathwayBrowser/#/R-SCE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 15763 R-SCE-197268 https://reactome.org/PathwayBrowser/#/R-SCE-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Saccharomyces cerevisiae 15763 R-SCE-200474 https://reactome.org/PathwayBrowser/#/R-SCE-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 15763 R-SCE-200512 https://reactome.org/PathwayBrowser/#/R-SCE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 15763 R-SPO-197186 https://reactome.org/PathwayBrowser/#/R-SPO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Schizosaccharomyces pombe 15763 R-SPO-197235 https://reactome.org/PathwayBrowser/#/R-SPO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 15763 R-SPO-200474 https://reactome.org/PathwayBrowser/#/R-SPO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 15763 R-SPO-200512 https://reactome.org/PathwayBrowser/#/R-SPO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 15763 R-SSC-197186 https://reactome.org/PathwayBrowser/#/R-SSC-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Sus scrofa 15763 R-SSC-197235 https://reactome.org/PathwayBrowser/#/R-SSC-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 15763 R-SSC-197250 https://reactome.org/PathwayBrowser/#/R-SSC-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Sus scrofa 15763 R-SSC-197268 https://reactome.org/PathwayBrowser/#/R-SSC-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Sus scrofa 15763 R-SSC-200474 https://reactome.org/PathwayBrowser/#/R-SSC-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 15763 R-SSC-200512 https://reactome.org/PathwayBrowser/#/R-SSC-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 15763 R-SSC-8869606 https://reactome.org/PathwayBrowser/#/R-SSC-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Sus scrofa 15763 R-SSC-8869607 https://reactome.org/PathwayBrowser/#/R-SSC-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Sus scrofa 15763 R-XTR-197250 https://reactome.org/PathwayBrowser/#/R-XTR-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Xenopus tropicalis 15763 R-XTR-197268 https://reactome.org/PathwayBrowser/#/R-XTR-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Xenopus tropicalis 15793 R-BTA-71217 https://reactome.org/PathwayBrowser/#/R-BTA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Bos taurus 15793 R-BTA-71218 https://reactome.org/PathwayBrowser/#/R-BTA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Bos taurus 15793 R-CEL-71217 https://reactome.org/PathwayBrowser/#/R-CEL-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Caenorhabditis elegans 15793 R-CEL-71218 https://reactome.org/PathwayBrowser/#/R-CEL-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Caenorhabditis elegans 15793 R-CFA-71217 https://reactome.org/PathwayBrowser/#/R-CFA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Canis familiaris 15793 R-CFA-71218 https://reactome.org/PathwayBrowser/#/R-CFA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Canis familiaris 15793 R-DDI-71217 https://reactome.org/PathwayBrowser/#/R-DDI-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Dictyostelium discoideum 15793 R-DDI-71218 https://reactome.org/PathwayBrowser/#/R-DDI-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Dictyostelium discoideum 15793 R-DRE-71218 https://reactome.org/PathwayBrowser/#/R-DRE-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Danio rerio 15793 R-GGA-71217 https://reactome.org/PathwayBrowser/#/R-GGA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Gallus gallus 15793 R-GGA-71218 https://reactome.org/PathwayBrowser/#/R-GGA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Gallus gallus 15793 R-HSA-71217 https://reactome.org/PathwayBrowser/#/R-HSA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine TAS Homo sapiens 15793 R-HSA-71218 https://reactome.org/PathwayBrowser/#/R-HSA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde TAS Homo sapiens 15793 R-MMU-71217 https://reactome.org/PathwayBrowser/#/R-MMU-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Mus musculus 15793 R-MMU-71218 https://reactome.org/PathwayBrowser/#/R-MMU-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Mus musculus 15793 R-RNO-71217 https://reactome.org/PathwayBrowser/#/R-RNO-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Rattus norvegicus 15793 R-RNO-71218 https://reactome.org/PathwayBrowser/#/R-RNO-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Rattus norvegicus 15793 R-SCE-71217 https://reactome.org/PathwayBrowser/#/R-SCE-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Saccharomyces cerevisiae 15793 R-SCE-71218 https://reactome.org/PathwayBrowser/#/R-SCE-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Saccharomyces cerevisiae 15793 R-SSC-71217 https://reactome.org/PathwayBrowser/#/R-SSC-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Sus scrofa 15793 R-SSC-71218 https://reactome.org/PathwayBrowser/#/R-SSC-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Sus scrofa 15793 R-XTR-71217 https://reactome.org/PathwayBrowser/#/R-XTR-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Xenopus tropicalis 15793 R-XTR-71218 https://reactome.org/PathwayBrowser/#/R-XTR-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Xenopus tropicalis 15811 R-BTA-977324 https://reactome.org/PathwayBrowser/#/R-BTA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Bos taurus 15811 R-BTA-977333 https://reactome.org/PathwayBrowser/#/R-BTA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Bos taurus 15811 R-CEL-977324 https://reactome.org/PathwayBrowser/#/R-CEL-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Caenorhabditis elegans 15811 R-CEL-977333 https://reactome.org/PathwayBrowser/#/R-CEL-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Caenorhabditis elegans 15811 R-CFA-977324 https://reactome.org/PathwayBrowser/#/R-CFA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Canis familiaris 15811 R-CFA-977333 https://reactome.org/PathwayBrowser/#/R-CFA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Canis familiaris 15811 R-DDI-977324 https://reactome.org/PathwayBrowser/#/R-DDI-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Dictyostelium discoideum 15811 R-DDI-977333 https://reactome.org/PathwayBrowser/#/R-DDI-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Dictyostelium discoideum 15811 R-DME-977324 https://reactome.org/PathwayBrowser/#/R-DME-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Drosophila melanogaster 15811 R-DME-977333 https://reactome.org/PathwayBrowser/#/R-DME-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Drosophila melanogaster 15811 R-DRE-977324 https://reactome.org/PathwayBrowser/#/R-DRE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Danio rerio 15811 R-DRE-977333 https://reactome.org/PathwayBrowser/#/R-DRE-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Danio rerio 15811 R-GGA-977324 https://reactome.org/PathwayBrowser/#/R-GGA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Gallus gallus 15811 R-GGA-977333 https://reactome.org/PathwayBrowser/#/R-GGA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Gallus gallus 15811 R-HSA-977324 https://reactome.org/PathwayBrowser/#/R-HSA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser TAS Homo sapiens 15811 R-HSA-977333 https://reactome.org/PathwayBrowser/#/R-HSA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA TAS Homo sapiens 15811 R-MMU-977324 https://reactome.org/PathwayBrowser/#/R-MMU-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Mus musculus 15811 R-MMU-977333 https://reactome.org/PathwayBrowser/#/R-MMU-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Mus musculus 15811 R-MTU-936665 https://reactome.org/PathwayBrowser/#/R-MTU-936665 OPS is added to the carrier sulfide TAS Mycobacterium tuberculosis 15811 R-RNO-977324 https://reactome.org/PathwayBrowser/#/R-RNO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Rattus norvegicus 15811 R-RNO-977333 https://reactome.org/PathwayBrowser/#/R-RNO-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Rattus norvegicus 15811 R-SCE-977324 https://reactome.org/PathwayBrowser/#/R-SCE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Saccharomyces cerevisiae 15811 R-SCE-977333 https://reactome.org/PathwayBrowser/#/R-SCE-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Saccharomyces cerevisiae 15811 R-SPO-977324 https://reactome.org/PathwayBrowser/#/R-SPO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Schizosaccharomyces pombe 15811 R-SPO-977333 https://reactome.org/PathwayBrowser/#/R-SPO-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Schizosaccharomyces pombe 15811 R-SSC-977324 https://reactome.org/PathwayBrowser/#/R-SSC-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Sus scrofa 15811 R-SSC-977333 https://reactome.org/PathwayBrowser/#/R-SSC-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Sus scrofa 15811 R-XTR-977324 https://reactome.org/PathwayBrowser/#/R-XTR-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Xenopus tropicalis 15811 R-XTR-977333 https://reactome.org/PathwayBrowser/#/R-XTR-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Xenopus tropicalis 15812 R-BTA-446189 https://reactome.org/PathwayBrowser/#/R-BTA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Bos taurus 15812 R-BTA-446202 https://reactome.org/PathwayBrowser/#/R-BTA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Bos taurus 15812 R-BTA-446214 https://reactome.org/PathwayBrowser/#/R-BTA-446214 Synthesis of dolichyl-phosphate-glucose IEA Bos taurus 15812 R-CEL-446189 https://reactome.org/PathwayBrowser/#/R-CEL-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Caenorhabditis elegans 15812 R-CEL-446202 https://reactome.org/PathwayBrowser/#/R-CEL-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Caenorhabditis elegans 15812 R-CEL-446214 https://reactome.org/PathwayBrowser/#/R-CEL-446214 Synthesis of dolichyl-phosphate-glucose IEA Caenorhabditis elegans 15812 R-CFA-446189 https://reactome.org/PathwayBrowser/#/R-CFA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Canis familiaris 15812 R-CFA-446202 https://reactome.org/PathwayBrowser/#/R-CFA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Canis familiaris 15812 R-CFA-446214 https://reactome.org/PathwayBrowser/#/R-CFA-446214 Synthesis of dolichyl-phosphate-glucose IEA Canis familiaris 15812 R-DDI-446189 https://reactome.org/PathwayBrowser/#/R-DDI-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Dictyostelium discoideum 15812 R-DDI-446202 https://reactome.org/PathwayBrowser/#/R-DDI-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Dictyostelium discoideum 15812 R-DDI-446214 https://reactome.org/PathwayBrowser/#/R-DDI-446214 Synthesis of dolichyl-phosphate-glucose IEA Dictyostelium discoideum 15812 R-DME-446189 https://reactome.org/PathwayBrowser/#/R-DME-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Drosophila melanogaster 15812 R-DME-446202 https://reactome.org/PathwayBrowser/#/R-DME-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Drosophila melanogaster 15812 R-DME-446214 https://reactome.org/PathwayBrowser/#/R-DME-446214 Synthesis of dolichyl-phosphate-glucose IEA Drosophila melanogaster 15812 R-DRE-446189 https://reactome.org/PathwayBrowser/#/R-DRE-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Danio rerio 15812 R-DRE-446214 https://reactome.org/PathwayBrowser/#/R-DRE-446214 Synthesis of dolichyl-phosphate-glucose IEA Danio rerio 15812 R-GGA-446189 https://reactome.org/PathwayBrowser/#/R-GGA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Gallus gallus 15812 R-GGA-446202 https://reactome.org/PathwayBrowser/#/R-GGA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Gallus gallus 15812 R-GGA-446214 https://reactome.org/PathwayBrowser/#/R-GGA-446214 Synthesis of dolichyl-phosphate-glucose IEA Gallus gallus 15812 R-HSA-446189 https://reactome.org/PathwayBrowser/#/R-HSA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 TAS Homo sapiens 15812 R-HSA-446194 https://reactome.org/PathwayBrowser/#/R-HSA-446194 Addition of a third glucose to the N-glycan precursor by an ALG10 homologue IEA Homo sapiens 15812 R-HSA-446202 https://reactome.org/PathwayBrowser/#/R-HSA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 TAS Homo sapiens 15812 R-HSA-446211 https://reactome.org/PathwayBrowser/#/R-HSA-446211 Flipping of dolichyl-phosphate-glucose into the ER lumen TAS Homo sapiens 15812 R-HSA-446214 https://reactome.org/PathwayBrowser/#/R-HSA-446214 Synthesis of dolichyl-phosphate-glucose TAS Homo sapiens 15812 R-HSA-4724291 https://reactome.org/PathwayBrowser/#/R-HSA-4724291 Defective ALG6 does not add glucose to the N-glycan precursor TAS Homo sapiens 15812 R-HSA-4724330 https://reactome.org/PathwayBrowser/#/R-HSA-4724330 Defective ALG8 does not add glucose to the N-glycan precursor TAS Homo sapiens 15812 R-HSA-548884 https://reactome.org/PathwayBrowser/#/R-HSA-548884 UGGT1,2 transfers glucose from DbGP to (un)folded protein:(GlcNAc)2 (Man)8b TAS Homo sapiens 15812 R-MMU-446189 https://reactome.org/PathwayBrowser/#/R-MMU-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Mus musculus 15812 R-MMU-446202 https://reactome.org/PathwayBrowser/#/R-MMU-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Mus musculus 15812 R-MMU-446214 https://reactome.org/PathwayBrowser/#/R-MMU-446214 Synthesis of dolichyl-phosphate-glucose IEA Mus musculus 15812 R-RNO-446189 https://reactome.org/PathwayBrowser/#/R-RNO-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Rattus norvegicus 15812 R-RNO-446202 https://reactome.org/PathwayBrowser/#/R-RNO-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Rattus norvegicus 15812 R-RNO-446214 https://reactome.org/PathwayBrowser/#/R-RNO-446214 Synthesis of dolichyl-phosphate-glucose IEA Rattus norvegicus 15812 R-SCE-446189 https://reactome.org/PathwayBrowser/#/R-SCE-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Saccharomyces cerevisiae 15812 R-SCE-446202 https://reactome.org/PathwayBrowser/#/R-SCE-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Saccharomyces cerevisiae 15812 R-SCE-446214 https://reactome.org/PathwayBrowser/#/R-SCE-446214 Synthesis of dolichyl-phosphate-glucose IEA Saccharomyces cerevisiae 15812 R-SCE-449661 https://reactome.org/PathwayBrowser/#/R-SCE-449661 Addition of a third glucose to the N-glycan skeleton by Alg10 TAS Saccharomyces cerevisiae 15812 R-SPO-446189 https://reactome.org/PathwayBrowser/#/R-SPO-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Schizosaccharomyces pombe 15812 R-SPO-446202 https://reactome.org/PathwayBrowser/#/R-SPO-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Schizosaccharomyces pombe 15812 R-SPO-446214 https://reactome.org/PathwayBrowser/#/R-SPO-446214 Synthesis of dolichyl-phosphate-glucose IEA Schizosaccharomyces pombe 15812 R-SSC-446189 https://reactome.org/PathwayBrowser/#/R-SSC-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Sus scrofa 15812 R-SSC-446202 https://reactome.org/PathwayBrowser/#/R-SSC-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Sus scrofa 15812 R-SSC-446214 https://reactome.org/PathwayBrowser/#/R-SSC-446214 Synthesis of dolichyl-phosphate-glucose IEA Sus scrofa 15812 R-XTR-446189 https://reactome.org/PathwayBrowser/#/R-XTR-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Xenopus tropicalis 15812 R-XTR-446202 https://reactome.org/PathwayBrowser/#/R-XTR-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Xenopus tropicalis 15812 R-XTR-446214 https://reactome.org/PathwayBrowser/#/R-XTR-446214 Synthesis of dolichyl-phosphate-glucose IEA Xenopus tropicalis 15817 R-BTA-6799722 https://reactome.org/PathwayBrowser/#/R-BTA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Bos taurus 15817 R-CFA-6799722 https://reactome.org/PathwayBrowser/#/R-CFA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Canis familiaris 15817 R-DDI-6799722 https://reactome.org/PathwayBrowser/#/R-DDI-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Dictyostelium discoideum 15817 R-GGA-6799722 https://reactome.org/PathwayBrowser/#/R-GGA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Gallus gallus 15817 R-HSA-6799722 https://reactome.org/PathwayBrowser/#/R-HSA-6799722 TP53I3 oxidoreductase generates unstable semiquinones TAS Homo sapiens 15817 R-HSA-6799733 https://reactome.org/PathwayBrowser/#/R-HSA-6799733 Semiquinone reacts with oxygen TAS Homo sapiens 15817 R-SSC-6799722 https://reactome.org/PathwayBrowser/#/R-SSC-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Sus scrofa 15817 R-XTR-6799722 https://reactome.org/PathwayBrowser/#/R-XTR-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Xenopus tropicalis 1582 R-BTA-379387 https://reactome.org/PathwayBrowser/#/R-BTA-379387 COMT transfers Met to DA to form 3MT IEA Bos taurus 1582 R-BTA-379395 https://reactome.org/PathwayBrowser/#/R-BTA-379395 MAOA:FAD deaminates 3MT to HVA IEA Bos taurus 1582 R-BTA-8955010 https://reactome.org/PathwayBrowser/#/R-BTA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Bos taurus 1582 R-CFA-379387 https://reactome.org/PathwayBrowser/#/R-CFA-379387 COMT transfers Met to DA to form 3MT IEA Canis familiaris 1582 R-CFA-379395 https://reactome.org/PathwayBrowser/#/R-CFA-379395 MAOA:FAD deaminates 3MT to HVA IEA Canis familiaris 1582 R-CFA-8955010 https://reactome.org/PathwayBrowser/#/R-CFA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Canis familiaris 1582 R-DDI-379395 https://reactome.org/PathwayBrowser/#/R-DDI-379395 MAOA:FAD deaminates 3MT to HVA IEA Dictyostelium discoideum 1582 R-DRE-379387 https://reactome.org/PathwayBrowser/#/R-DRE-379387 COMT transfers Met to DA to form 3MT IEA Danio rerio 1582 R-DRE-8955010 https://reactome.org/PathwayBrowser/#/R-DRE-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Danio rerio 1582 R-GGA-379387 https://reactome.org/PathwayBrowser/#/R-GGA-379387 COMT transfers Met to DA to form 3MT IEA Gallus gallus 1582 R-GGA-379395 https://reactome.org/PathwayBrowser/#/R-GGA-379395 MAOA:FAD deaminates 3MT to HVA IEA Gallus gallus 1582 R-GGA-8955010 https://reactome.org/PathwayBrowser/#/R-GGA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Gallus gallus 1582 R-HSA-379387 https://reactome.org/PathwayBrowser/#/R-HSA-379387 COMT transfers Met to DA to form 3MT TAS Homo sapiens 1582 R-HSA-379395 https://reactome.org/PathwayBrowser/#/R-HSA-379395 MAOA:FAD deaminates 3MT to HVA TAS Homo sapiens 1582 R-HSA-8955010 https://reactome.org/PathwayBrowser/#/R-HSA-8955010 LRTOMT transfers Met to DA, forming 3MT TAS Homo sapiens 1582 R-MMU-379387 https://reactome.org/PathwayBrowser/#/R-MMU-379387 COMT transfers Met to DA to form 3MT IEA Mus musculus 1582 R-MMU-379395 https://reactome.org/PathwayBrowser/#/R-MMU-379395 MAOA:FAD deaminates 3MT to HVA IEA Mus musculus 1582 R-MMU-8955010 https://reactome.org/PathwayBrowser/#/R-MMU-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Mus musculus 1582 R-RNO-379387 https://reactome.org/PathwayBrowser/#/R-RNO-379387 COMT transfers Met to DA to form 3MT IEA Rattus norvegicus 1582 R-RNO-379395 https://reactome.org/PathwayBrowser/#/R-RNO-379395 MAOA:FAD deaminates 3MT to HVA IEA Rattus norvegicus 1582 R-RNO-8955010 https://reactome.org/PathwayBrowser/#/R-RNO-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Rattus norvegicus 1582 R-SPO-379387 https://reactome.org/PathwayBrowser/#/R-SPO-379387 COMT transfers Met to DA to form 3MT IEA Schizosaccharomyces pombe 1582 R-SPO-8955010 https://reactome.org/PathwayBrowser/#/R-SPO-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Schizosaccharomyces pombe 1582 R-SSC-379387 https://reactome.org/PathwayBrowser/#/R-SSC-379387 COMT transfers Met to DA to form 3MT IEA Sus scrofa 1582 R-SSC-379395 https://reactome.org/PathwayBrowser/#/R-SSC-379395 MAOA:FAD deaminates 3MT to HVA IEA Sus scrofa 1582 R-SSC-8955010 https://reactome.org/PathwayBrowser/#/R-SSC-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Sus scrofa 1582 R-XTR-379387 https://reactome.org/PathwayBrowser/#/R-XTR-379387 COMT transfers Met to DA to form 3MT IEA Xenopus tropicalis 15824 R-BTA-189069 https://reactome.org/PathwayBrowser/#/R-BTA-189069 sucrose + H2O => glucose + fructose IEA Bos taurus 15824 R-BTA-189222 https://reactome.org/PathwayBrowser/#/R-BTA-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Bos taurus 15824 R-BTA-189242 https://reactome.org/PathwayBrowser/#/R-BTA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Bos taurus 15824 R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 15824 R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 15824 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 15824 R-BTA-428779 https://reactome.org/PathwayBrowser/#/R-BTA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Bos taurus 15824 R-BTA-429036 https://reactome.org/PathwayBrowser/#/R-BTA-429036 SLC2A9 transports Fru, Glc, urate IEA Bos taurus 15824 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 15824 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 15824 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 15824 R-BTA-8876283 https://reactome.org/PathwayBrowser/#/R-BTA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Bos taurus 15824 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 15824 R-CEL-189069 https://reactome.org/PathwayBrowser/#/R-CEL-189069 sucrose + H2O => glucose + fructose IEA Caenorhabditis elegans 15824 R-CEL-189222 https://reactome.org/PathwayBrowser/#/R-CEL-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Caenorhabditis elegans 15824 R-CEL-189242 https://reactome.org/PathwayBrowser/#/R-CEL-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Caenorhabditis elegans 15824 R-CEL-428779 https://reactome.org/PathwayBrowser/#/R-CEL-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Caenorhabditis elegans 15824 R-CEL-429036 https://reactome.org/PathwayBrowser/#/R-CEL-429036 SLC2A9 transports Fru, Glc, urate IEA Caenorhabditis elegans 15824 R-CFA-189069 https://reactome.org/PathwayBrowser/#/R-CFA-189069 sucrose + H2O => glucose + fructose IEA Canis familiaris 15824 R-CFA-189222 https://reactome.org/PathwayBrowser/#/R-CFA-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Canis familiaris 15824 R-CFA-189242 https://reactome.org/PathwayBrowser/#/R-CFA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Canis familiaris 15824 R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 15824 R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 15824 R-CFA-428779 https://reactome.org/PathwayBrowser/#/R-CFA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Canis familiaris 15824 R-CFA-429036 https://reactome.org/PathwayBrowser/#/R-CFA-429036 SLC2A9 transports Fru, Glc, urate IEA Canis familiaris 15824 R-CFA-8876283 https://reactome.org/PathwayBrowser/#/R-CFA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Canis familiaris 15824 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 15824 R-DDI-189069 https://reactome.org/PathwayBrowser/#/R-DDI-189069 sucrose + H2O => glucose + fructose IEA Dictyostelium discoideum 15824 R-DDI-189222 https://reactome.org/PathwayBrowser/#/R-DDI-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Dictyostelium discoideum 15824 R-DDI-189242 https://reactome.org/PathwayBrowser/#/R-DDI-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Dictyostelium discoideum 15824 R-DDI-428779 https://reactome.org/PathwayBrowser/#/R-DDI-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Dictyostelium discoideum 15824 R-DDI-429036 https://reactome.org/PathwayBrowser/#/R-DDI-429036 SLC2A9 transports Fru, Glc, urate IEA Dictyostelium discoideum 15824 R-DME-189222 https://reactome.org/PathwayBrowser/#/R-DME-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Drosophila melanogaster 15824 R-DME-189242 https://reactome.org/PathwayBrowser/#/R-DME-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Drosophila melanogaster 15824 R-DME-428779 https://reactome.org/PathwayBrowser/#/R-DME-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Drosophila melanogaster 15824 R-DME-429036 https://reactome.org/PathwayBrowser/#/R-DME-429036 SLC2A9 transports Fru, Glc, urate IEA Drosophila melanogaster 15824 R-DRE-189242 https://reactome.org/PathwayBrowser/#/R-DRE-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Danio rerio 15824 R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 15824 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 15824 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 15824 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 15824 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 15824 R-GGA-189069 https://reactome.org/PathwayBrowser/#/R-GGA-189069 sucrose + H2O => glucose + fructose IEA Gallus gallus 15824 R-GGA-189222 https://reactome.org/PathwayBrowser/#/R-GGA-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Gallus gallus 15824 R-GGA-189242 https://reactome.org/PathwayBrowser/#/R-GGA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Gallus gallus 15824 R-GGA-428779 https://reactome.org/PathwayBrowser/#/R-GGA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Gallus gallus 15824 R-GGA-429036 https://reactome.org/PathwayBrowser/#/R-GGA-429036 SLC2A9 transports Fru, Glc, urate IEA Gallus gallus 15824 R-GGA-8876283 https://reactome.org/PathwayBrowser/#/R-GGA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Gallus gallus 15824 R-HSA-189069 https://reactome.org/PathwayBrowser/#/R-HSA-189069 sucrose + H2O => glucose + fructose TAS Homo sapiens 15824 R-HSA-189222 https://reactome.org/PathwayBrowser/#/R-HSA-189222 SLC2A5 transports fructose from extracellular region to cytosol TAS Homo sapiens 15824 R-HSA-189242 https://reactome.org/PathwayBrowser/#/R-HSA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region TAS Homo sapiens 15824 R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 15824 R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 15824 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 15824 R-HSA-428779 https://reactome.org/PathwayBrowser/#/R-HSA-428779 GLUT7 and GLUT11 transport glucose and fructose TAS Homo sapiens 15824 R-HSA-429036 https://reactome.org/PathwayBrowser/#/R-HSA-429036 SLC2A9 transports Fru, Glc, urate TAS Homo sapiens 15824 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 15824 R-HSA-5638209 https://reactome.org/PathwayBrowser/#/R-HSA-5638209 Defective SLC2A9 does not transport Fru, Glc, urate TAS Homo sapiens 15824 R-HSA-5638222 https://reactome.org/PathwayBrowser/#/R-HSA-5638222 Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region TAS Homo sapiens 15824 R-HSA-5656459 https://reactome.org/PathwayBrowser/#/R-HSA-5656459 Defective KHK does not phosphorylate beta-D-fructose TAS Homo sapiens 15824 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 15824 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 15824 R-HSA-8876283 https://reactome.org/PathwayBrowser/#/R-HSA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol TAS Homo sapiens 15824 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 15824 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 15824 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 15824 R-MMU-189069 https://reactome.org/PathwayBrowser/#/R-MMU-189069 sucrose + H2O => glucose + fructose IEA Mus musculus 15824 R-MMU-189222 https://reactome.org/PathwayBrowser/#/R-MMU-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Mus musculus 15824 R-MMU-189242 https://reactome.org/PathwayBrowser/#/R-MMU-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Mus musculus 15824 R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 15824 R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 15824 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 15824 R-MMU-428779 https://reactome.org/PathwayBrowser/#/R-MMU-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Mus musculus 15824 R-MMU-429036 https://reactome.org/PathwayBrowser/#/R-MMU-429036 SLC2A9 transports Fru, Glc, urate IEA Mus musculus 15824 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 15824 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 15824 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 15824 R-MMU-8876283 https://reactome.org/PathwayBrowser/#/R-MMU-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Mus musculus 15824 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 15824 R-PFA-189222 https://reactome.org/PathwayBrowser/#/R-PFA-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Plasmodium falciparum 15824 R-PFA-189242 https://reactome.org/PathwayBrowser/#/R-PFA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Plasmodium falciparum 15824 R-PFA-428779 https://reactome.org/PathwayBrowser/#/R-PFA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Plasmodium falciparum 15824 R-PFA-429036 https://reactome.org/PathwayBrowser/#/R-PFA-429036 SLC2A9 transports Fru, Glc, urate IEA Plasmodium falciparum 15824 R-RNO-189069 https://reactome.org/PathwayBrowser/#/R-RNO-189069 sucrose + H2O => glucose + fructose IEA Rattus norvegicus 15824 R-RNO-189222 https://reactome.org/PathwayBrowser/#/R-RNO-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Rattus norvegicus 15824 R-RNO-189242 https://reactome.org/PathwayBrowser/#/R-RNO-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Rattus norvegicus 15824 R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 15824 R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 15824 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 15824 R-RNO-428779 https://reactome.org/PathwayBrowser/#/R-RNO-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Rattus norvegicus 15824 R-RNO-429036 https://reactome.org/PathwayBrowser/#/R-RNO-429036 SLC2A9 transports Fru, Glc, urate IEA Rattus norvegicus 15824 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 15824 R-RNO-8876283 https://reactome.org/PathwayBrowser/#/R-RNO-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Rattus norvegicus 15824 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 15824 R-SCE-189222 https://reactome.org/PathwayBrowser/#/R-SCE-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Saccharomyces cerevisiae 15824 R-SCE-189242 https://reactome.org/PathwayBrowser/#/R-SCE-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Saccharomyces cerevisiae 15824 R-SCE-428779 https://reactome.org/PathwayBrowser/#/R-SCE-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Saccharomyces cerevisiae 15824 R-SCE-429036 https://reactome.org/PathwayBrowser/#/R-SCE-429036 SLC2A9 transports Fru, Glc, urate IEA Saccharomyces cerevisiae 15824 R-SPO-189069 https://reactome.org/PathwayBrowser/#/R-SPO-189069 sucrose + H2O => glucose + fructose IEA Schizosaccharomyces pombe 15824 R-SSC-189069 https://reactome.org/PathwayBrowser/#/R-SSC-189069 sucrose + H2O => glucose + fructose IEA Sus scrofa 15824 R-SSC-189222 https://reactome.org/PathwayBrowser/#/R-SSC-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Sus scrofa 15824 R-SSC-189242 https://reactome.org/PathwayBrowser/#/R-SSC-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Sus scrofa 15824 R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 15824 R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 15824 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 15824 R-SSC-428779 https://reactome.org/PathwayBrowser/#/R-SSC-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Sus scrofa 15824 R-SSC-429036 https://reactome.org/PathwayBrowser/#/R-SSC-429036 SLC2A9 transports Fru, Glc, urate IEA Sus scrofa 15824 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 15824 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 15824 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 15824 R-SSC-8876283 https://reactome.org/PathwayBrowser/#/R-SSC-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Sus scrofa 15824 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 15824 R-XTR-189222 https://reactome.org/PathwayBrowser/#/R-XTR-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Xenopus tropicalis 15824 R-XTR-189242 https://reactome.org/PathwayBrowser/#/R-XTR-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Xenopus tropicalis 15824 R-XTR-428779 https://reactome.org/PathwayBrowser/#/R-XTR-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Xenopus tropicalis 15824 R-XTR-429036 https://reactome.org/PathwayBrowser/#/R-XTR-429036 SLC2A9 transports Fru, Glc, urate IEA Xenopus tropicalis 15824 R-XTR-8876283 https://reactome.org/PathwayBrowser/#/R-XTR-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Xenopus tropicalis 15841 R-BTA-1236965 https://reactome.org/PathwayBrowser/#/R-BTA-1236965 Export of peptide loaded MHC class I complex to PM IEA Bos taurus 15841 R-BTA-1799332 https://reactome.org/PathwayBrowser/#/R-BTA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Bos taurus 15841 R-BTA-2130706 https://reactome.org/PathwayBrowser/#/R-BTA-2130706 MHC class II antigen processing IEA Bos taurus 15841 R-BTA-2213244 https://reactome.org/PathwayBrowser/#/R-BTA-2213244 Loading of antigenic peptides IEA Bos taurus 15841 R-BTA-2213248 https://reactome.org/PathwayBrowser/#/R-BTA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Bos taurus 15841 R-BTA-3371422 https://reactome.org/PathwayBrowser/#/R-BTA-3371422 ATP hydrolysis by HSP70 IEA Bos taurus 15841 R-BTA-3371503 https://reactome.org/PathwayBrowser/#/R-BTA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Bos taurus 15841 R-BTA-3371590 https://reactome.org/PathwayBrowser/#/R-BTA-3371590 HSP70 binds to HSP40:nascent protein IEA Bos taurus 15841 R-BTA-5223317 https://reactome.org/PathwayBrowser/#/R-BTA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Bos taurus 15841 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 15841 R-BTA-5618085 https://reactome.org/PathwayBrowser/#/R-BTA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Bos taurus 15841 R-BTA-5618098 https://reactome.org/PathwayBrowser/#/R-BTA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Bos taurus 15841 R-BTA-5618105 https://reactome.org/PathwayBrowser/#/R-BTA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Bos taurus 15841 R-BTA-5618107 https://reactome.org/PathwayBrowser/#/R-BTA-5618107 ATP binding to HSP90 triggers conformation change IEA Bos taurus 15841 R-BTA-5618110 https://reactome.org/PathwayBrowser/#/R-BTA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Bos taurus 15841 R-BTA-8848658 https://reactome.org/PathwayBrowser/#/R-BTA-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Bos taurus 15841 R-BTA-983421 https://reactome.org/PathwayBrowser/#/R-BTA-983421 Journey of cargo through Golgi complex IEA Bos taurus 15841 R-BTA-983422 https://reactome.org/PathwayBrowser/#/R-BTA-983422 Disassembly of COPII coated vesicle IEA Bos taurus 15841 R-BTA-983424 https://reactome.org/PathwayBrowser/#/R-BTA-983424 Budding of COPII coated vesicle IEA Bos taurus 15841 R-BTA-983427 https://reactome.org/PathwayBrowser/#/R-BTA-983427 Expression of peptide bound class I MHC on cell surface IEA Bos taurus 15841 R-CEL-1799332 https://reactome.org/PathwayBrowser/#/R-CEL-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Caenorhabditis elegans 15841 R-CEL-2130706 https://reactome.org/PathwayBrowser/#/R-CEL-2130706 MHC class II antigen processing IEA Caenorhabditis elegans 15841 R-CEL-3371422 https://reactome.org/PathwayBrowser/#/R-CEL-3371422 ATP hydrolysis by HSP70 IEA Caenorhabditis elegans 15841 R-CEL-3371503 https://reactome.org/PathwayBrowser/#/R-CEL-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Caenorhabditis elegans 15841 R-CEL-3371590 https://reactome.org/PathwayBrowser/#/R-CEL-3371590 HSP70 binds to HSP40:nascent protein IEA Caenorhabditis elegans 15841 R-CEL-5223317 https://reactome.org/PathwayBrowser/#/R-CEL-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 15841 R-CEL-5618107 https://reactome.org/PathwayBrowser/#/R-CEL-5618107 ATP binding to HSP90 triggers conformation change IEA Caenorhabditis elegans 15841 R-CFA-1236965 https://reactome.org/PathwayBrowser/#/R-CFA-1236965 Export of peptide loaded MHC class I complex to PM IEA Canis familiaris 15841 R-CFA-1799332 https://reactome.org/PathwayBrowser/#/R-CFA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Canis familiaris 15841 R-CFA-2130706 https://reactome.org/PathwayBrowser/#/R-CFA-2130706 MHC class II antigen processing IEA Canis familiaris 15841 R-CFA-2213244 https://reactome.org/PathwayBrowser/#/R-CFA-2213244 Loading of antigenic peptides IEA Canis familiaris 15841 R-CFA-2213248 https://reactome.org/PathwayBrowser/#/R-CFA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Canis familiaris 15841 R-CFA-3371422 https://reactome.org/PathwayBrowser/#/R-CFA-3371422 ATP hydrolysis by HSP70 IEA Canis familiaris 15841 R-CFA-3371503 https://reactome.org/PathwayBrowser/#/R-CFA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Canis familiaris 15841 R-CFA-3371590 https://reactome.org/PathwayBrowser/#/R-CFA-3371590 HSP70 binds to HSP40:nascent protein IEA Canis familiaris 15841 R-CFA-5223317 https://reactome.org/PathwayBrowser/#/R-CFA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Canis familiaris 15841 R-CFA-5618085 https://reactome.org/PathwayBrowser/#/R-CFA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Canis familiaris 15841 R-CFA-5618107 https://reactome.org/PathwayBrowser/#/R-CFA-5618107 ATP binding to HSP90 triggers conformation change IEA Canis familiaris 15841 R-CFA-8848658 https://reactome.org/PathwayBrowser/#/R-CFA-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Canis familiaris 15841 R-CFA-983421 https://reactome.org/PathwayBrowser/#/R-CFA-983421 Journey of cargo through Golgi complex IEA Canis familiaris 15841 R-CFA-983422 https://reactome.org/PathwayBrowser/#/R-CFA-983422 Disassembly of COPII coated vesicle IEA Canis familiaris 15841 R-CFA-983424 https://reactome.org/PathwayBrowser/#/R-CFA-983424 Budding of COPII coated vesicle IEA Canis familiaris 15841 R-CFA-983427 https://reactome.org/PathwayBrowser/#/R-CFA-983427 Expression of peptide bound class I MHC on cell surface IEA Canis familiaris 15841 R-DDI-1799332 https://reactome.org/PathwayBrowser/#/R-DDI-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Dictyostelium discoideum 15841 R-DDI-2130706 https://reactome.org/PathwayBrowser/#/R-DDI-2130706 MHC class II antigen processing IEA Dictyostelium discoideum 15841 R-DDI-3371422 https://reactome.org/PathwayBrowser/#/R-DDI-3371422 ATP hydrolysis by HSP70 IEA Dictyostelium discoideum 15841 R-DDI-3371503 https://reactome.org/PathwayBrowser/#/R-DDI-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Dictyostelium discoideum 15841 R-DDI-3371590 https://reactome.org/PathwayBrowser/#/R-DDI-3371590 HSP70 binds to HSP40:nascent protein IEA Dictyostelium discoideum 15841 R-DDI-5618107 https://reactome.org/PathwayBrowser/#/R-DDI-5618107 ATP binding to HSP90 triggers conformation change IEA Dictyostelium discoideum 15841 R-DME-1799332 https://reactome.org/PathwayBrowser/#/R-DME-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Drosophila melanogaster 15841 R-DME-2130706 https://reactome.org/PathwayBrowser/#/R-DME-2130706 MHC class II antigen processing IEA Drosophila melanogaster 15841 R-DME-3371422 https://reactome.org/PathwayBrowser/#/R-DME-3371422 ATP hydrolysis by HSP70 IEA Drosophila melanogaster 15841 R-DME-3371503 https://reactome.org/PathwayBrowser/#/R-DME-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Drosophila melanogaster 15841 R-DME-3371590 https://reactome.org/PathwayBrowser/#/R-DME-3371590 HSP70 binds to HSP40:nascent protein IEA Drosophila melanogaster 15841 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 15841 R-DME-5618085 https://reactome.org/PathwayBrowser/#/R-DME-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Drosophila melanogaster 15841 R-DME-5618098 https://reactome.org/PathwayBrowser/#/R-DME-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Drosophila melanogaster 15841 R-DME-5618105 https://reactome.org/PathwayBrowser/#/R-DME-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Drosophila melanogaster 15841 R-DME-5618107 https://reactome.org/PathwayBrowser/#/R-DME-5618107 ATP binding to HSP90 triggers conformation change IEA Drosophila melanogaster 15841 R-DME-5618110 https://reactome.org/PathwayBrowser/#/R-DME-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Drosophila melanogaster 15841 R-DRE-1236965 https://reactome.org/PathwayBrowser/#/R-DRE-1236965 Export of peptide loaded MHC class I complex to PM IEA Danio rerio 15841 R-DRE-1799332 https://reactome.org/PathwayBrowser/#/R-DRE-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Danio rerio 15841 R-DRE-2130706 https://reactome.org/PathwayBrowser/#/R-DRE-2130706 MHC class II antigen processing IEA Danio rerio 15841 R-DRE-2213244 https://reactome.org/PathwayBrowser/#/R-DRE-2213244 Loading of antigenic peptides IEA Danio rerio 15841 R-DRE-3371422 https://reactome.org/PathwayBrowser/#/R-DRE-3371422 ATP hydrolysis by HSP70 IEA Danio rerio 15841 R-DRE-3371503 https://reactome.org/PathwayBrowser/#/R-DRE-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Danio rerio 15841 R-DRE-3371590 https://reactome.org/PathwayBrowser/#/R-DRE-3371590 HSP70 binds to HSP40:nascent protein IEA Danio rerio 15841 R-DRE-5223317 https://reactome.org/PathwayBrowser/#/R-DRE-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Danio rerio 15841 R-DRE-5618107 https://reactome.org/PathwayBrowser/#/R-DRE-5618107 ATP binding to HSP90 triggers conformation change IEA Danio rerio 15841 R-DRE-8848658 https://reactome.org/PathwayBrowser/#/R-DRE-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Danio rerio 15841 R-DRE-983421 https://reactome.org/PathwayBrowser/#/R-DRE-983421 Journey of cargo through Golgi complex IEA Danio rerio 15841 R-DRE-983424 https://reactome.org/PathwayBrowser/#/R-DRE-983424 Budding of COPII coated vesicle IEA Danio rerio 15841 R-DRE-983427 https://reactome.org/PathwayBrowser/#/R-DRE-983427 Expression of peptide bound class I MHC on cell surface IEA Danio rerio 15841 R-GGA-1236965 https://reactome.org/PathwayBrowser/#/R-GGA-1236965 Export of peptide loaded MHC class I complex to PM IEA Gallus gallus 15841 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus 15841 R-GGA-2130706 https://reactome.org/PathwayBrowser/#/R-GGA-2130706 MHC class II antigen processing IEA Gallus gallus 15841 R-GGA-3371422 https://reactome.org/PathwayBrowser/#/R-GGA-3371422 ATP hydrolysis by HSP70 IEA Gallus gallus 15841 R-GGA-3371503 https://reactome.org/PathwayBrowser/#/R-GGA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Gallus gallus 15841 R-GGA-3371590 https://reactome.org/PathwayBrowser/#/R-GGA-3371590 HSP70 binds to HSP40:nascent protein IEA Gallus gallus 15841 R-GGA-5223317 https://reactome.org/PathwayBrowser/#/R-GGA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Gallus gallus 15841 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 15841 R-GGA-5618085 https://reactome.org/PathwayBrowser/#/R-GGA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Gallus gallus 15841 R-GGA-5618098 https://reactome.org/PathwayBrowser/#/R-GGA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Gallus gallus 15841 R-GGA-5618105 https://reactome.org/PathwayBrowser/#/R-GGA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Gallus gallus 15841 R-GGA-5618107 https://reactome.org/PathwayBrowser/#/R-GGA-5618107 ATP binding to HSP90 triggers conformation change IEA Gallus gallus 15841 R-GGA-5618110 https://reactome.org/PathwayBrowser/#/R-GGA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Gallus gallus 15841 R-GGA-983421 https://reactome.org/PathwayBrowser/#/R-GGA-983421 Journey of cargo through Golgi complex IEA Gallus gallus 15841 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus 15841 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus 15841 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus 15841 R-HSA-1222363 https://reactome.org/PathwayBrowser/#/R-HSA-1222363 MsrA/B reduces peptide-methionine S/R-sulfoxides TAS Homo sapiens 15841 R-HSA-1222411 https://reactome.org/PathwayBrowser/#/R-HSA-1222411 Peroxynitrite oxidizes Peptide-Methionine residues TAS Homo sapiens 15841 R-HSA-1236949 https://reactome.org/PathwayBrowser/#/R-HSA-1236949 Translocation of antigenic peptides back to phagosomes via TAP IEA Homo sapiens 15841 R-HSA-1236965 https://reactome.org/PathwayBrowser/#/R-HSA-1236965 Export of peptide loaded MHC class I complex to PM TAS Homo sapiens 15841 R-HSA-1236971 https://reactome.org/PathwayBrowser/#/R-HSA-1236971 Peptide loading on MHC class I in phagosome IEA Homo sapiens 15841 R-HSA-1799326 https://reactome.org/PathwayBrowser/#/R-HSA-1799326 Signal-containing nascent peptide translocates to endoplasmic reticulum IEA Homo sapiens 15841 R-HSA-1799329 https://reactome.org/PathwayBrowser/#/R-HSA-1799329 Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein IEA Homo sapiens 15841 R-HSA-1799330 https://reactome.org/PathwayBrowser/#/R-HSA-1799330 The SRP receptor binds the SRP:nascent peptide:ribosome complex IEA Homo sapiens 15841 R-HSA-1799332 https://reactome.org/PathwayBrowser/#/R-HSA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) TAS Homo sapiens 15841 R-HSA-1799335 https://reactome.org/PathwayBrowser/#/R-HSA-1799335 Synthesis of nascent polypeptide containing signal sequence TAS Homo sapiens 15841 R-HSA-2130706 https://reactome.org/PathwayBrowser/#/R-HSA-2130706 MHC class II antigen processing TAS Homo sapiens 15841 R-HSA-2213244 https://reactome.org/PathwayBrowser/#/R-HSA-2213244 Loading of antigenic peptides TAS Homo sapiens 15841 R-HSA-2213248 https://reactome.org/PathwayBrowser/#/R-HSA-2213248 Transport of antigen loaded MHC II molecules to surface TAS Homo sapiens 15841 R-HSA-3371422 https://reactome.org/PathwayBrowser/#/R-HSA-3371422 ATP hydrolysis by HSP70 TAS Homo sapiens 15841 R-HSA-3371503 https://reactome.org/PathwayBrowser/#/R-HSA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein TAS Homo sapiens 15841 R-HSA-3371590 https://reactome.org/PathwayBrowser/#/R-HSA-3371590 HSP70 binds to HSP40:nascent protein TAS Homo sapiens 15841 R-HSA-5223317 https://reactome.org/PathwayBrowser/#/R-HSA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen TAS Homo sapiens 15841 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 15841 R-HSA-5618085 https://reactome.org/PathwayBrowser/#/R-HSA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein TAS Homo sapiens 15841 R-HSA-5618098 https://reactome.org/PathwayBrowser/#/R-HSA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein TAS Homo sapiens 15841 R-HSA-5618105 https://reactome.org/PathwayBrowser/#/R-HSA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein TAS Homo sapiens 15841 R-HSA-5618107 https://reactome.org/PathwayBrowser/#/R-HSA-5618107 ATP binding to HSP90 triggers conformation change TAS Homo sapiens 15841 R-HSA-5618110 https://reactome.org/PathwayBrowser/#/R-HSA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein TAS Homo sapiens 15841 R-HSA-6803978 https://reactome.org/PathwayBrowser/#/R-HSA-6803978 S-nitrosylation of cysteine residues in proteins by N2O3 TAS Homo sapiens 15841 R-HSA-8848658 https://reactome.org/PathwayBrowser/#/R-HSA-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins TAS Homo sapiens 15841 R-HSA-8941411 https://reactome.org/PathwayBrowser/#/R-HSA-8941411 OSCN- reacts with Cys residues TAS Homo sapiens 15841 R-HSA-8948180 https://reactome.org/PathwayBrowser/#/R-HSA-8948180 Peroxynitrite oxidizes Cys residues TAS Homo sapiens 15841 R-HSA-9625540 https://reactome.org/PathwayBrowser/#/R-HSA-9625540 Cys-sulfenyl chloride is converted to Cys-sulfenic acid TAS Homo sapiens 15841 R-HSA-9625548 https://reactome.org/PathwayBrowser/#/R-HSA-9625548 Hypochlorous acid (HOCL) oxidizes Cys residues to form Cys-sulfenyl chloride TAS Homo sapiens 15841 R-HSA-9625904 https://reactome.org/PathwayBrowser/#/R-HSA-9625904 Hypochlorous acid (HOCL) reacts with Lys residue to form Lys-monochloramine TAS Homo sapiens 15841 R-HSA-9625913 https://reactome.org/PathwayBrowser/#/R-HSA-9625913 Hypochlorous acid (HOCL) reacts with Lys-monochloramine TAS Homo sapiens 15841 R-HSA-9626753 https://reactome.org/PathwayBrowser/#/R-HSA-9626753 H2O2 oxidizes Cys residues to form Cys-sulfenic acid TAS Homo sapiens 15841 R-HSA-983421 https://reactome.org/PathwayBrowser/#/R-HSA-983421 Journey of cargo through Golgi complex TAS Homo sapiens 15841 R-HSA-983422 https://reactome.org/PathwayBrowser/#/R-HSA-983422 Disassembly of COPII coated vesicle TAS Homo sapiens 15841 R-HSA-983424 https://reactome.org/PathwayBrowser/#/R-HSA-983424 Budding of COPII coated vesicle TAS Homo sapiens 15841 R-HSA-983427 https://reactome.org/PathwayBrowser/#/R-HSA-983427 Expression of peptide bound class I MHC on cell surface TAS Homo sapiens 15841 R-MMU-1236965 https://reactome.org/PathwayBrowser/#/R-MMU-1236965 Export of peptide loaded MHC class I complex to PM IEA Mus musculus 15841 R-MMU-1799332 https://reactome.org/PathwayBrowser/#/R-MMU-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Mus musculus 15841 R-MMU-2130706 https://reactome.org/PathwayBrowser/#/R-MMU-2130706 MHC class II antigen processing IEA Mus musculus 15841 R-MMU-2213244 https://reactome.org/PathwayBrowser/#/R-MMU-2213244 Loading of antigenic peptides IEA Mus musculus 15841 R-MMU-2213248 https://reactome.org/PathwayBrowser/#/R-MMU-2213248 Transport of antigen loaded MHC II molecules to surface IEA Mus musculus 15841 R-MMU-3371422 https://reactome.org/PathwayBrowser/#/R-MMU-3371422 ATP hydrolysis by HSP70 IEA Mus musculus 15841 R-MMU-3371503 https://reactome.org/PathwayBrowser/#/R-MMU-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Mus musculus 15841 R-MMU-3371590 https://reactome.org/PathwayBrowser/#/R-MMU-3371590 HSP70 binds to HSP40:nascent protein IEA Mus musculus 15841 R-MMU-5223317 https://reactome.org/PathwayBrowser/#/R-MMU-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Mus musculus 15841 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 15841 R-MMU-5618085 https://reactome.org/PathwayBrowser/#/R-MMU-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Mus musculus 15841 R-MMU-5618098 https://reactome.org/PathwayBrowser/#/R-MMU-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Mus musculus 15841 R-MMU-5618105 https://reactome.org/PathwayBrowser/#/R-MMU-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Mus musculus 15841 R-MMU-5618107 https://reactome.org/PathwayBrowser/#/R-MMU-5618107 ATP binding to HSP90 triggers conformation change IEA Mus musculus 15841 R-MMU-5618110 https://reactome.org/PathwayBrowser/#/R-MMU-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Mus musculus 15841 R-MMU-8848658 https://reactome.org/PathwayBrowser/#/R-MMU-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Mus musculus 15841 R-MMU-983421 https://reactome.org/PathwayBrowser/#/R-MMU-983421 Journey of cargo through Golgi complex IEA Mus musculus 15841 R-MMU-983422 https://reactome.org/PathwayBrowser/#/R-MMU-983422 Disassembly of COPII coated vesicle IEA Mus musculus 15841 R-MMU-983424 https://reactome.org/PathwayBrowser/#/R-MMU-983424 Budding of COPII coated vesicle IEA Mus musculus 15841 R-MMU-983427 https://reactome.org/PathwayBrowser/#/R-MMU-983427 Expression of peptide bound class I MHC on cell surface IEA Mus musculus 15841 R-PFA-1799332 https://reactome.org/PathwayBrowser/#/R-PFA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Plasmodium falciparum 15841 R-PFA-2130706 https://reactome.org/PathwayBrowser/#/R-PFA-2130706 MHC class II antigen processing IEA Plasmodium falciparum 15841 R-PFA-3371422 https://reactome.org/PathwayBrowser/#/R-PFA-3371422 ATP hydrolysis by HSP70 IEA Plasmodium falciparum 15841 R-PFA-3371503 https://reactome.org/PathwayBrowser/#/R-PFA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Plasmodium falciparum 15841 R-PFA-3371590 https://reactome.org/PathwayBrowser/#/R-PFA-3371590 HSP70 binds to HSP40:nascent protein IEA Plasmodium falciparum 15841 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 15841 R-PFA-5618085 https://reactome.org/PathwayBrowser/#/R-PFA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Plasmodium falciparum 15841 R-PFA-5618098 https://reactome.org/PathwayBrowser/#/R-PFA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Plasmodium falciparum 15841 R-PFA-5618105 https://reactome.org/PathwayBrowser/#/R-PFA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Plasmodium falciparum 15841 R-PFA-5618107 https://reactome.org/PathwayBrowser/#/R-PFA-5618107 ATP binding to HSP90 triggers conformation change IEA Plasmodium falciparum 15841 R-PFA-5618110 https://reactome.org/PathwayBrowser/#/R-PFA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Plasmodium falciparum 15841 R-RNO-1236965 https://reactome.org/PathwayBrowser/#/R-RNO-1236965 Export of peptide loaded MHC class I complex to PM IEA Rattus norvegicus 15841 R-RNO-1799332 https://reactome.org/PathwayBrowser/#/R-RNO-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Rattus norvegicus 15841 R-RNO-2130706 https://reactome.org/PathwayBrowser/#/R-RNO-2130706 MHC class II antigen processing IEA Rattus norvegicus 15841 R-RNO-2213244 https://reactome.org/PathwayBrowser/#/R-RNO-2213244 Loading of antigenic peptides IEA Rattus norvegicus 15841 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus 15841 R-RNO-3371422 https://reactome.org/PathwayBrowser/#/R-RNO-3371422 ATP hydrolysis by HSP70 IEA Rattus norvegicus 15841 R-RNO-3371503 https://reactome.org/PathwayBrowser/#/R-RNO-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Rattus norvegicus 15841 R-RNO-3371590 https://reactome.org/PathwayBrowser/#/R-RNO-3371590 HSP70 binds to HSP40:nascent protein IEA Rattus norvegicus 15841 R-RNO-5223317 https://reactome.org/PathwayBrowser/#/R-RNO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Rattus norvegicus 15841 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 15841 R-RNO-5618085 https://reactome.org/PathwayBrowser/#/R-RNO-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Rattus norvegicus 15841 R-RNO-5618098 https://reactome.org/PathwayBrowser/#/R-RNO-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Rattus norvegicus 15841 R-RNO-5618105 https://reactome.org/PathwayBrowser/#/R-RNO-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Rattus norvegicus 15841 R-RNO-5618107 https://reactome.org/PathwayBrowser/#/R-RNO-5618107 ATP binding to HSP90 triggers conformation change IEA Rattus norvegicus 15841 R-RNO-5618110 https://reactome.org/PathwayBrowser/#/R-RNO-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Rattus norvegicus 15841 R-RNO-8848658 https://reactome.org/PathwayBrowser/#/R-RNO-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Rattus norvegicus 15841 R-RNO-983421 https://reactome.org/PathwayBrowser/#/R-RNO-983421 Journey of cargo through Golgi complex IEA Rattus norvegicus 15841 R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus 15841 R-RNO-983424 https://reactome.org/PathwayBrowser/#/R-RNO-983424 Budding of COPII coated vesicle IEA Rattus norvegicus 15841 R-RNO-983427 https://reactome.org/PathwayBrowser/#/R-RNO-983427 Expression of peptide bound class I MHC on cell surface IEA Rattus norvegicus 15841 R-SCE-1799332 https://reactome.org/PathwayBrowser/#/R-SCE-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Saccharomyces cerevisiae 15841 R-SCE-3371422 https://reactome.org/PathwayBrowser/#/R-SCE-3371422 ATP hydrolysis by HSP70 IEA Saccharomyces cerevisiae 15841 R-SCE-3371503 https://reactome.org/PathwayBrowser/#/R-SCE-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Saccharomyces cerevisiae 15841 R-SCE-3371590 https://reactome.org/PathwayBrowser/#/R-SCE-3371590 HSP70 binds to HSP40:nascent protein IEA Saccharomyces cerevisiae 15841 R-SCE-5618107 https://reactome.org/PathwayBrowser/#/R-SCE-5618107 ATP binding to HSP90 triggers conformation change IEA Saccharomyces cerevisiae 15841 R-SPO-1799332 https://reactome.org/PathwayBrowser/#/R-SPO-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Schizosaccharomyces pombe 15841 R-SPO-3371422 https://reactome.org/PathwayBrowser/#/R-SPO-3371422 ATP hydrolysis by HSP70 IEA Schizosaccharomyces pombe 15841 R-SPO-3371503 https://reactome.org/PathwayBrowser/#/R-SPO-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Schizosaccharomyces pombe 15841 R-SPO-3371590 https://reactome.org/PathwayBrowser/#/R-SPO-3371590 HSP70 binds to HSP40:nascent protein IEA Schizosaccharomyces pombe 15841 R-SPO-5223317 https://reactome.org/PathwayBrowser/#/R-SPO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 15841 R-SPO-5618107 https://reactome.org/PathwayBrowser/#/R-SPO-5618107 ATP binding to HSP90 triggers conformation change IEA Schizosaccharomyces pombe 15841 R-SSC-1236965 https://reactome.org/PathwayBrowser/#/R-SSC-1236965 Export of peptide loaded MHC class I complex to PM IEA Sus scrofa 15841 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa 15841 R-SSC-2130706 https://reactome.org/PathwayBrowser/#/R-SSC-2130706 MHC class II antigen processing IEA Sus scrofa 15841 R-SSC-2213244 https://reactome.org/PathwayBrowser/#/R-SSC-2213244 Loading of antigenic peptides IEA Sus scrofa 15841 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa 15841 R-SSC-3371422 https://reactome.org/PathwayBrowser/#/R-SSC-3371422 ATP hydrolysis by HSP70 IEA Sus scrofa 15841 R-SSC-3371503 https://reactome.org/PathwayBrowser/#/R-SSC-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Sus scrofa 15841 R-SSC-3371590 https://reactome.org/PathwayBrowser/#/R-SSC-3371590 HSP70 binds to HSP40:nascent protein IEA Sus scrofa 15841 R-SSC-5223317 https://reactome.org/PathwayBrowser/#/R-SSC-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Sus scrofa 15841 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 15841 R-SSC-5618085 https://reactome.org/PathwayBrowser/#/R-SSC-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Sus scrofa 15841 R-SSC-5618098 https://reactome.org/PathwayBrowser/#/R-SSC-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Sus scrofa 15841 R-SSC-5618105 https://reactome.org/PathwayBrowser/#/R-SSC-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Sus scrofa 15841 R-SSC-5618107 https://reactome.org/PathwayBrowser/#/R-SSC-5618107 ATP binding to HSP90 triggers conformation change IEA Sus scrofa 15841 R-SSC-5618110 https://reactome.org/PathwayBrowser/#/R-SSC-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Sus scrofa 15841 R-SSC-8848658 https://reactome.org/PathwayBrowser/#/R-SSC-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Sus scrofa 15841 R-SSC-983421 https://reactome.org/PathwayBrowser/#/R-SSC-983421 Journey of cargo through Golgi complex IEA Sus scrofa 15841 R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa 15841 R-SSC-983424 https://reactome.org/PathwayBrowser/#/R-SSC-983424 Budding of COPII coated vesicle IEA Sus scrofa 15841 R-SSC-983427 https://reactome.org/PathwayBrowser/#/R-SSC-983427 Expression of peptide bound class I MHC on cell surface IEA Sus scrofa 15841 R-XTR-1799332 https://reactome.org/PathwayBrowser/#/R-XTR-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Xenopus tropicalis 15841 R-XTR-2130706 https://reactome.org/PathwayBrowser/#/R-XTR-2130706 MHC class II antigen processing IEA Xenopus tropicalis 15841 R-XTR-2213244 https://reactome.org/PathwayBrowser/#/R-XTR-2213244 Loading of antigenic peptides IEA Xenopus tropicalis 15841 R-XTR-3371422 https://reactome.org/PathwayBrowser/#/R-XTR-3371422 ATP hydrolysis by HSP70 IEA Xenopus tropicalis 15841 R-XTR-3371503 https://reactome.org/PathwayBrowser/#/R-XTR-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Xenopus tropicalis 15841 R-XTR-3371590 https://reactome.org/PathwayBrowser/#/R-XTR-3371590 HSP70 binds to HSP40:nascent protein IEA Xenopus tropicalis 15841 R-XTR-5618107 https://reactome.org/PathwayBrowser/#/R-XTR-5618107 ATP binding to HSP90 triggers conformation change IEA Xenopus tropicalis 15841 R-XTR-8848658 https://reactome.org/PathwayBrowser/#/R-XTR-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Xenopus tropicalis 15841 R-XTR-983424 https://reactome.org/PathwayBrowser/#/R-XTR-983424 Budding of COPII coated vesicle IEA Xenopus tropicalis 15854 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 15854 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 15854 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 15854 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 15854 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 15854 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 15854 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 15854 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 15854 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 15854 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 15854 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 15854 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 15854 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 15854 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 15854 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 15854 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 15854 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 15854 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 15854 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 15854 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 15854 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 15854 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 15854 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 15854 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 15854 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 15854 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 15854 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 15854 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 15854 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 15854 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 15854 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 15854 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 15854 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 15854 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 15854 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 15854 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 15854 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 15854 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 15854 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 15854 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 15854 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 15854 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 15854 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 15854 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 15854 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 15854 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 15854 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 15854 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 15854 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 15854 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 15854 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 15854 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 15854 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 15854 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 15854 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 15854 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 15854 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 15854 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 15854 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 15854 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 15854 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 15854 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 15854 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 15854 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 15857 R-HSA-1222712 https://reactome.org/PathwayBrowser/#/R-HSA-1222712 Nitrosoglutathione gets cleaved to Cys(NO)-Gly TAS Homo sapiens 15858 R-BTA-2559639 https://reactome.org/PathwayBrowser/#/R-BTA-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Bos taurus 15858 R-CFA-2559639 https://reactome.org/PathwayBrowser/#/R-CFA-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Canis familiaris 15858 R-GGA-2559639 https://reactome.org/PathwayBrowser/#/R-GGA-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Gallus gallus 15858 R-HSA-2559639 https://reactome.org/PathwayBrowser/#/R-HSA-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin TAS Homo sapiens 15858 R-HSA-432034 https://reactome.org/PathwayBrowser/#/R-HSA-432034 Aquaporin-6 passively transports anions into vesicles IEA Homo sapiens 15858 R-HSA-432036 https://reactome.org/PathwayBrowser/#/R-HSA-432036 Aquaporin-6 passively transports anions out of vesicles IEA Homo sapiens 15858 R-MMU-2559639 https://reactome.org/PathwayBrowser/#/R-MMU-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Mus musculus 15858 R-RNO-2559639 https://reactome.org/PathwayBrowser/#/R-RNO-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Rattus norvegicus 15858 R-RNO-879862 https://reactome.org/PathwayBrowser/#/R-RNO-879862 Passive Transport of Anions into Vesicles by Aquaporin-6 (rat) TAS Rattus norvegicus 15858 R-RNO-879863 https://reactome.org/PathwayBrowser/#/R-RNO-879863 Passive Transport of Anions out of Vesicles by Aquaporin-6 (rat) TAS Rattus norvegicus 15858 R-SSC-2559639 https://reactome.org/PathwayBrowser/#/R-SSC-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Sus scrofa 15858 R-XTR-2559639 https://reactome.org/PathwayBrowser/#/R-XTR-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Xenopus tropicalis 15873 R-BTA-449715 https://reactome.org/PathwayBrowser/#/R-BTA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Bos taurus 15873 R-BTA-449734 https://reactome.org/PathwayBrowser/#/R-BTA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Bos taurus 15873 R-BTA-6799604 https://reactome.org/PathwayBrowser/#/R-BTA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Bos taurus 15873 R-BTA-6803789 https://reactome.org/PathwayBrowser/#/R-BTA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Bos taurus 15873 R-CEL-449715 https://reactome.org/PathwayBrowser/#/R-CEL-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Caenorhabditis elegans 15873 R-CEL-449734 https://reactome.org/PathwayBrowser/#/R-CEL-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Caenorhabditis elegans 15873 R-CEL-6799604 https://reactome.org/PathwayBrowser/#/R-CEL-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Caenorhabditis elegans 15873 R-CEL-6803789 https://reactome.org/PathwayBrowser/#/R-CEL-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Caenorhabditis elegans 15873 R-CFA-449715 https://reactome.org/PathwayBrowser/#/R-CFA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Canis familiaris 15873 R-CFA-449734 https://reactome.org/PathwayBrowser/#/R-CFA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Canis familiaris 15873 R-CFA-6799604 https://reactome.org/PathwayBrowser/#/R-CFA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Canis familiaris 15873 R-CFA-6803789 https://reactome.org/PathwayBrowser/#/R-CFA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Canis familiaris 15873 R-DDI-449715 https://reactome.org/PathwayBrowser/#/R-DDI-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Dictyostelium discoideum 15873 R-DDI-449734 https://reactome.org/PathwayBrowser/#/R-DDI-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Dictyostelium discoideum 15873 R-DDI-6799604 https://reactome.org/PathwayBrowser/#/R-DDI-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Dictyostelium discoideum 15873 R-DME-449715 https://reactome.org/PathwayBrowser/#/R-DME-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Drosophila melanogaster 15873 R-DME-449734 https://reactome.org/PathwayBrowser/#/R-DME-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Drosophila melanogaster 15873 R-DME-6799604 https://reactome.org/PathwayBrowser/#/R-DME-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Drosophila melanogaster 15873 R-DME-6803789 https://reactome.org/PathwayBrowser/#/R-DME-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Drosophila melanogaster 15873 R-DRE-449715 https://reactome.org/PathwayBrowser/#/R-DRE-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Danio rerio 15873 R-DRE-449734 https://reactome.org/PathwayBrowser/#/R-DRE-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Danio rerio 15873 R-DRE-6799604 https://reactome.org/PathwayBrowser/#/R-DRE-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Danio rerio 15873 R-DRE-6803789 https://reactome.org/PathwayBrowser/#/R-DRE-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Danio rerio 15873 R-GGA-449715 https://reactome.org/PathwayBrowser/#/R-GGA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Gallus gallus 15873 R-GGA-449734 https://reactome.org/PathwayBrowser/#/R-GGA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Gallus gallus 15873 R-GGA-6799604 https://reactome.org/PathwayBrowser/#/R-GGA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Gallus gallus 15873 R-GGA-6803789 https://reactome.org/PathwayBrowser/#/R-GGA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Gallus gallus 15873 R-HSA-449715 https://reactome.org/PathwayBrowser/#/R-HSA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P TAS Homo sapiens 15873 R-HSA-449734 https://reactome.org/PathwayBrowser/#/R-HSA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P TAS Homo sapiens 15873 R-HSA-6799604 https://reactome.org/PathwayBrowser/#/R-HSA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P TAS Homo sapiens 15873 R-HSA-6803789 https://reactome.org/PathwayBrowser/#/R-HSA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA TAS Homo sapiens 15873 R-MMU-449715 https://reactome.org/PathwayBrowser/#/R-MMU-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Mus musculus 15873 R-MMU-449734 https://reactome.org/PathwayBrowser/#/R-MMU-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Mus musculus 15873 R-MMU-6799604 https://reactome.org/PathwayBrowser/#/R-MMU-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Mus musculus 15873 R-MMU-6803789 https://reactome.org/PathwayBrowser/#/R-MMU-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Mus musculus 15873 R-PFA-449715 https://reactome.org/PathwayBrowser/#/R-PFA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Plasmodium falciparum 15873 R-RNO-449715 https://reactome.org/PathwayBrowser/#/R-RNO-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Rattus norvegicus 15873 R-RNO-449734 https://reactome.org/PathwayBrowser/#/R-RNO-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Rattus norvegicus 15873 R-RNO-6799604 https://reactome.org/PathwayBrowser/#/R-RNO-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Rattus norvegicus 15873 R-RNO-6803789 https://reactome.org/PathwayBrowser/#/R-RNO-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Rattus norvegicus 15873 R-SCE-449715 https://reactome.org/PathwayBrowser/#/R-SCE-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Saccharomyces cerevisiae 15873 R-SCE-449734 https://reactome.org/PathwayBrowser/#/R-SCE-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Saccharomyces cerevisiae 15873 R-SPO-449715 https://reactome.org/PathwayBrowser/#/R-SPO-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Schizosaccharomyces pombe 15873 R-SPO-449734 https://reactome.org/PathwayBrowser/#/R-SPO-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Schizosaccharomyces pombe 15873 R-SSC-449715 https://reactome.org/PathwayBrowser/#/R-SSC-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Sus scrofa 15873 R-SSC-449734 https://reactome.org/PathwayBrowser/#/R-SSC-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Sus scrofa 15873 R-SSC-6799604 https://reactome.org/PathwayBrowser/#/R-SSC-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Sus scrofa 15873 R-SSC-6803789 https://reactome.org/PathwayBrowser/#/R-SSC-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Sus scrofa 15873 R-XTR-449715 https://reactome.org/PathwayBrowser/#/R-XTR-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Xenopus tropicalis 15873 R-XTR-449734 https://reactome.org/PathwayBrowser/#/R-XTR-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Xenopus tropicalis 15873 R-XTR-6799604 https://reactome.org/PathwayBrowser/#/R-XTR-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Xenopus tropicalis 15873 R-XTR-6803789 https://reactome.org/PathwayBrowser/#/R-XTR-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Xenopus tropicalis 15882 R-BTA-158849 https://reactome.org/PathwayBrowser/#/R-BTA-158849 Phenol can form a sulfate conjugate IEA Bos taurus 15882 R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 15882 R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 15882 R-CFA-158849 https://reactome.org/PathwayBrowser/#/R-CFA-158849 Phenol can form a sulfate conjugate IEA Canis familiaris 15882 R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 15882 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 15882 R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 15882 R-DME-158849 https://reactome.org/PathwayBrowser/#/R-DME-158849 Phenol can form a sulfate conjugate IEA Drosophila melanogaster 15882 R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 15882 R-DRE-158849 https://reactome.org/PathwayBrowser/#/R-DRE-158849 Phenol can form a sulfate conjugate IEA Danio rerio 15882 R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 15882 R-GGA-158849 https://reactome.org/PathwayBrowser/#/R-GGA-158849 Phenol can form a sulfate conjugate IEA Gallus gallus 15882 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 15882 R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 15882 R-HSA-158849 https://reactome.org/PathwayBrowser/#/R-HSA-158849 Phenol can form a sulfate conjugate TAS Homo sapiens 15882 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 15882 R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 15882 R-MMU-158849 https://reactome.org/PathwayBrowser/#/R-MMU-158849 Phenol can form a sulfate conjugate IEA Mus musculus 15882 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 15882 R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 15882 R-RNO-158849 https://reactome.org/PathwayBrowser/#/R-RNO-158849 Phenol can form a sulfate conjugate IEA Rattus norvegicus 15882 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 15882 R-RNO-76416 https://reactome.org/PathwayBrowser/#/R-RNO-76416 Benzene is hydroxylated to phenol IEA Rattus norvegicus 15882 R-SSC-158849 https://reactome.org/PathwayBrowser/#/R-SSC-158849 Phenol can form a sulfate conjugate IEA Sus scrofa 15882 R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa 15882 R-XTR-158849 https://reactome.org/PathwayBrowser/#/R-XTR-158849 Phenol can form a sulfate conjugate IEA Xenopus tropicalis 15882 R-XTR-76416 https://reactome.org/PathwayBrowser/#/R-XTR-76416 Benzene is hydroxylated to phenol IEA Xenopus tropicalis 15883 R-BTA-5696197 https://reactome.org/PathwayBrowser/#/R-BTA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Bos taurus 15883 R-CEL-5696197 https://reactome.org/PathwayBrowser/#/R-CEL-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Caenorhabditis elegans 15883 R-CFA-5696197 https://reactome.org/PathwayBrowser/#/R-CFA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Canis familiaris 15883 R-DME-5696197 https://reactome.org/PathwayBrowser/#/R-DME-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Drosophila melanogaster 15883 R-DRE-5696197 https://reactome.org/PathwayBrowser/#/R-DRE-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Danio rerio 15883 R-GGA-5696197 https://reactome.org/PathwayBrowser/#/R-GGA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Gallus gallus 15883 R-HSA-5696197 https://reactome.org/PathwayBrowser/#/R-HSA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP TAS Homo sapiens 15883 R-MMU-5696197 https://reactome.org/PathwayBrowser/#/R-MMU-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Mus musculus 15883 R-PFA-5696197 https://reactome.org/PathwayBrowser/#/R-PFA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Plasmodium falciparum 15883 R-RNO-5696197 https://reactome.org/PathwayBrowser/#/R-RNO-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Rattus norvegicus 15883 R-SSC-5696197 https://reactome.org/PathwayBrowser/#/R-SSC-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Sus scrofa 15883 R-XTR-5696197 https://reactome.org/PathwayBrowser/#/R-XTR-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Xenopus tropicalis 15899 R-BTA-191414 https://reactome.org/PathwayBrowser/#/R-BTA-191414 MVD decarboxylates MVA5PP to IPPP IEA Bos taurus 15899 R-BTA-191422 https://reactome.org/PathwayBrowser/#/R-BTA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Bos taurus 15899 R-CEL-191414 https://reactome.org/PathwayBrowser/#/R-CEL-191414 MVD decarboxylates MVA5PP to IPPP IEA Caenorhabditis elegans 15899 R-CEL-191422 https://reactome.org/PathwayBrowser/#/R-CEL-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Caenorhabditis elegans 15899 R-CFA-191414 https://reactome.org/PathwayBrowser/#/R-CFA-191414 MVD decarboxylates MVA5PP to IPPP IEA Canis familiaris 15899 R-CFA-191422 https://reactome.org/PathwayBrowser/#/R-CFA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Canis familiaris 15899 R-DDI-191414 https://reactome.org/PathwayBrowser/#/R-DDI-191414 MVD decarboxylates MVA5PP to IPPP IEA Dictyostelium discoideum 15899 R-DME-191414 https://reactome.org/PathwayBrowser/#/R-DME-191414 MVD decarboxylates MVA5PP to IPPP IEA Drosophila melanogaster 15899 R-DME-191422 https://reactome.org/PathwayBrowser/#/R-DME-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Drosophila melanogaster 15899 R-DRE-191414 https://reactome.org/PathwayBrowser/#/R-DRE-191414 MVD decarboxylates MVA5PP to IPPP IEA Danio rerio 15899 R-DRE-191422 https://reactome.org/PathwayBrowser/#/R-DRE-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Danio rerio 15899 R-GGA-191414 https://reactome.org/PathwayBrowser/#/R-GGA-191414 MVD decarboxylates MVA5PP to IPPP IEA Gallus gallus 15899 R-GGA-191422 https://reactome.org/PathwayBrowser/#/R-GGA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Gallus gallus 15899 R-HSA-191414 https://reactome.org/PathwayBrowser/#/R-HSA-191414 MVD decarboxylates MVA5PP to IPPP TAS Homo sapiens 15899 R-HSA-191422 https://reactome.org/PathwayBrowser/#/R-HSA-191422 Mevalonate-5-phosphate is further phosphorylated. TAS Homo sapiens 15899 R-MMU-191414 https://reactome.org/PathwayBrowser/#/R-MMU-191414 MVD decarboxylates MVA5PP to IPPP IEA Mus musculus 15899 R-MMU-191422 https://reactome.org/PathwayBrowser/#/R-MMU-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Mus musculus 15899 R-RNO-191414 https://reactome.org/PathwayBrowser/#/R-RNO-191414 MVD decarboxylates MVA5PP to IPPP IEA Rattus norvegicus 15899 R-RNO-191422 https://reactome.org/PathwayBrowser/#/R-RNO-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Rattus norvegicus 15899 R-SCE-191414 https://reactome.org/PathwayBrowser/#/R-SCE-191414 MVD decarboxylates MVA5PP to IPPP IEA Saccharomyces cerevisiae 15899 R-SPO-191414 https://reactome.org/PathwayBrowser/#/R-SPO-191414 MVD decarboxylates MVA5PP to IPPP IEA Schizosaccharomyces pombe 15899 R-SSC-191414 https://reactome.org/PathwayBrowser/#/R-SSC-191414 MVD decarboxylates MVA5PP to IPPP IEA Sus scrofa 15899 R-SSC-191422 https://reactome.org/PathwayBrowser/#/R-SSC-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Sus scrofa 15899 R-XTR-191414 https://reactome.org/PathwayBrowser/#/R-XTR-191414 MVD decarboxylates MVA5PP to IPPP IEA Xenopus tropicalis 15901 R-BTA-110227 https://reactome.org/PathwayBrowser/#/R-BTA-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Bos taurus 15901 R-BTA-5649658 https://reactome.org/PathwayBrowser/#/R-BTA-5649658 NEIL1 cleaves DHU from damaged DNA IEA Bos taurus 15901 R-BTA-73585 https://reactome.org/PathwayBrowser/#/R-BTA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Bos taurus 15901 R-BTA-73589 https://reactome.org/PathwayBrowser/#/R-BTA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Bos taurus 15901 R-CEL-110227 https://reactome.org/PathwayBrowser/#/R-CEL-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Caenorhabditis elegans 15901 R-CEL-73585 https://reactome.org/PathwayBrowser/#/R-CEL-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Caenorhabditis elegans 15901 R-CEL-73589 https://reactome.org/PathwayBrowser/#/R-CEL-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Caenorhabditis elegans 15901 R-CFA-110227 https://reactome.org/PathwayBrowser/#/R-CFA-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Canis familiaris 15901 R-CFA-5649658 https://reactome.org/PathwayBrowser/#/R-CFA-5649658 NEIL1 cleaves DHU from damaged DNA IEA Canis familiaris 15901 R-CFA-73585 https://reactome.org/PathwayBrowser/#/R-CFA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Canis familiaris 15901 R-CFA-73589 https://reactome.org/PathwayBrowser/#/R-CFA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Canis familiaris 15901 R-DDI-110227 https://reactome.org/PathwayBrowser/#/R-DDI-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Dictyostelium discoideum 15901 R-DDI-73585 https://reactome.org/PathwayBrowser/#/R-DDI-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Dictyostelium discoideum 15901 R-DDI-73589 https://reactome.org/PathwayBrowser/#/R-DDI-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Dictyostelium discoideum 15901 R-DME-110227 https://reactome.org/PathwayBrowser/#/R-DME-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Drosophila melanogaster 15901 R-DME-73585 https://reactome.org/PathwayBrowser/#/R-DME-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Drosophila melanogaster 15901 R-DME-73589 https://reactome.org/PathwayBrowser/#/R-DME-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Drosophila melanogaster 15901 R-DRE-5649658 https://reactome.org/PathwayBrowser/#/R-DRE-5649658 NEIL1 cleaves DHU from damaged DNA IEA Danio rerio 15901 R-DRE-73585 https://reactome.org/PathwayBrowser/#/R-DRE-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Danio rerio 15901 R-DRE-73589 https://reactome.org/PathwayBrowser/#/R-DRE-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Danio rerio 15901 R-GGA-110227 https://reactome.org/PathwayBrowser/#/R-GGA-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Gallus gallus 15901 R-GGA-5649658 https://reactome.org/PathwayBrowser/#/R-GGA-5649658 NEIL1 cleaves DHU from damaged DNA IEA Gallus gallus 15901 R-GGA-73585 https://reactome.org/PathwayBrowser/#/R-GGA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Gallus gallus 15901 R-GGA-73589 https://reactome.org/PathwayBrowser/#/R-GGA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Gallus gallus 15901 R-HSA-110227 https://reactome.org/PathwayBrowser/#/R-HSA-110227 Cleavage of dihydrouracil by NTHL1 glycosylase TAS Homo sapiens 15901 R-HSA-5649658 https://reactome.org/PathwayBrowser/#/R-HSA-5649658 NEIL1 cleaves DHU from damaged DNA TAS Homo sapiens 15901 R-HSA-73585 https://reactome.org/PathwayBrowser/#/R-HSA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ TAS Homo sapiens 15901 R-HSA-73589 https://reactome.org/PathwayBrowser/#/R-HSA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate TAS Homo sapiens 15901 R-MMU-110227 https://reactome.org/PathwayBrowser/#/R-MMU-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Mus musculus 15901 R-MMU-5649658 https://reactome.org/PathwayBrowser/#/R-MMU-5649658 NEIL1 cleaves DHU from damaged DNA IEA Mus musculus 15901 R-MMU-73585 https://reactome.org/PathwayBrowser/#/R-MMU-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Mus musculus 15901 R-MMU-73589 https://reactome.org/PathwayBrowser/#/R-MMU-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Mus musculus 15901 R-PFA-110227 https://reactome.org/PathwayBrowser/#/R-PFA-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Plasmodium falciparum 15901 R-RNO-110227 https://reactome.org/PathwayBrowser/#/R-RNO-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Rattus norvegicus 15901 R-RNO-5649658 https://reactome.org/PathwayBrowser/#/R-RNO-5649658 NEIL1 cleaves DHU from damaged DNA IEA Rattus norvegicus 15901 R-RNO-73585 https://reactome.org/PathwayBrowser/#/R-RNO-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Rattus norvegicus 15901 R-RNO-73589 https://reactome.org/PathwayBrowser/#/R-RNO-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Rattus norvegicus 15901 R-SCE-110227 https://reactome.org/PathwayBrowser/#/R-SCE-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Saccharomyces cerevisiae 15901 R-SPO-110227 https://reactome.org/PathwayBrowser/#/R-SPO-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Schizosaccharomyces pombe 15901 R-SSC-110227 https://reactome.org/PathwayBrowser/#/R-SSC-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Sus scrofa 15901 R-SSC-5649658 https://reactome.org/PathwayBrowser/#/R-SSC-5649658 NEIL1 cleaves DHU from damaged DNA IEA Sus scrofa 15901 R-SSC-73585 https://reactome.org/PathwayBrowser/#/R-SSC-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Sus scrofa 15901 R-SSC-73589 https://reactome.org/PathwayBrowser/#/R-SSC-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Sus scrofa 15901 R-XTR-110227 https://reactome.org/PathwayBrowser/#/R-XTR-110227 Cleavage of dihydrouracil by NTHL1 glycosylase IEA Xenopus tropicalis 15901 R-XTR-5649658 https://reactome.org/PathwayBrowser/#/R-XTR-5649658 NEIL1 cleaves DHU from damaged DNA IEA Xenopus tropicalis 15901 R-XTR-73585 https://reactome.org/PathwayBrowser/#/R-XTR-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Xenopus tropicalis 15903 R-HSA-9683663 https://reactome.org/PathwayBrowser/#/R-HSA-9683663 N-glycan trimming of Spike TAS Homo sapiens 15903 R-HSA-9694364 https://reactome.org/PathwayBrowser/#/R-HSA-9694364 N-glycan glucose trimming of Spike TAS Homo sapiens 15904 R-BTA-170026 https://reactome.org/PathwayBrowser/#/R-BTA-170026 Protons are translocated from the intermembrane space to the matrix IEA Bos taurus 15904 R-BTA-174757 https://reactome.org/PathwayBrowser/#/R-BTA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Bos taurus 15904 R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 15904 R-BTA-192422 https://reactome.org/PathwayBrowser/#/R-BTA-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Bos taurus 15904 R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 15904 R-BTA-192430 https://reactome.org/PathwayBrowser/#/R-BTA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 15904 R-BTA-192434 https://reactome.org/PathwayBrowser/#/R-BTA-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Bos taurus 15904 R-BTA-192475 https://reactome.org/PathwayBrowser/#/R-BTA-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Bos taurus 15904 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 15904 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 15904 R-BTA-382575 https://reactome.org/PathwayBrowser/#/R-BTA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Bos taurus 15904 R-BTA-5690042 https://reactome.org/PathwayBrowser/#/R-BTA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 15904 R-BTA-5690043 https://reactome.org/PathwayBrowser/#/R-BTA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 15904 R-BTA-5690066 https://reactome.org/PathwayBrowser/#/R-BTA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 15904 R-BTA-8979996 https://reactome.org/PathwayBrowser/#/R-BTA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Bos taurus 15904 R-BTA-8980228 https://reactome.org/PathwayBrowser/#/R-BTA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Bos taurus 15904 R-CEL-170026 https://reactome.org/PathwayBrowser/#/R-CEL-170026 Protons are translocated from the intermembrane space to the matrix IEA Caenorhabditis elegans 15904 R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 15904 R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 15904 R-CEL-192430 https://reactome.org/PathwayBrowser/#/R-CEL-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 15904 R-CEL-382575 https://reactome.org/PathwayBrowser/#/R-CEL-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Caenorhabditis elegans 15904 R-CEL-5690042 https://reactome.org/PathwayBrowser/#/R-CEL-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 15904 R-CEL-5690043 https://reactome.org/PathwayBrowser/#/R-CEL-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 15904 R-CEL-5690066 https://reactome.org/PathwayBrowser/#/R-CEL-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 15904 R-CFA-170026 https://reactome.org/PathwayBrowser/#/R-CFA-170026 Protons are translocated from the intermembrane space to the matrix IEA Canis familiaris 15904 R-CFA-174757 https://reactome.org/PathwayBrowser/#/R-CFA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Canis familiaris 15904 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 15904 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 15904 R-CFA-382575 https://reactome.org/PathwayBrowser/#/R-CFA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Canis familiaris 15904 R-CFA-5690042 https://reactome.org/PathwayBrowser/#/R-CFA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 15904 R-CFA-5690043 https://reactome.org/PathwayBrowser/#/R-CFA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 15904 R-CFA-5690066 https://reactome.org/PathwayBrowser/#/R-CFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 15904 R-CFA-8979996 https://reactome.org/PathwayBrowser/#/R-CFA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Canis familiaris 15904 R-CFA-8980228 https://reactome.org/PathwayBrowser/#/R-CFA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Canis familiaris 15904 R-DDI-382575 https://reactome.org/PathwayBrowser/#/R-DDI-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Dictyostelium discoideum 15904 R-DDI-5690043 https://reactome.org/PathwayBrowser/#/R-DDI-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 15904 R-DDI-5690066 https://reactome.org/PathwayBrowser/#/R-DDI-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 15904 R-DDI-8979996 https://reactome.org/PathwayBrowser/#/R-DDI-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Dictyostelium discoideum 15904 R-DME-170026 https://reactome.org/PathwayBrowser/#/R-DME-170026 Protons are translocated from the intermembrane space to the matrix IEA Drosophila melanogaster 15904 R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 15904 R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 15904 R-DME-192430 https://reactome.org/PathwayBrowser/#/R-DME-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 15904 R-DME-192475 https://reactome.org/PathwayBrowser/#/R-DME-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Drosophila melanogaster 15904 R-DME-382575 https://reactome.org/PathwayBrowser/#/R-DME-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Drosophila melanogaster 15904 R-DME-5690043 https://reactome.org/PathwayBrowser/#/R-DME-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 15904 R-DME-5690066 https://reactome.org/PathwayBrowser/#/R-DME-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 15904 R-DME-8980228 https://reactome.org/PathwayBrowser/#/R-DME-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Drosophila melanogaster 15904 R-DRE-170026 https://reactome.org/PathwayBrowser/#/R-DRE-170026 Protons are translocated from the intermembrane space to the matrix IEA Danio rerio 15904 R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 15904 R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 15904 R-DRE-192430 https://reactome.org/PathwayBrowser/#/R-DRE-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 15904 R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 15904 R-DRE-382575 https://reactome.org/PathwayBrowser/#/R-DRE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Danio rerio 15904 R-DRE-5690042 https://reactome.org/PathwayBrowser/#/R-DRE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 15904 R-DRE-5690066 https://reactome.org/PathwayBrowser/#/R-DRE-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 15904 R-DRE-8980228 https://reactome.org/PathwayBrowser/#/R-DRE-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Danio rerio 15904 R-GGA-170026 https://reactome.org/PathwayBrowser/#/R-GGA-170026 Protons are translocated from the intermembrane space to the matrix IEA Gallus gallus 15904 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 15904 R-GGA-192422 https://reactome.org/PathwayBrowser/#/R-GGA-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Gallus gallus 15904 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 15904 R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 15904 R-GGA-192434 https://reactome.org/PathwayBrowser/#/R-GGA-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Gallus gallus 15904 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 15904 R-GGA-382575 https://reactome.org/PathwayBrowser/#/R-GGA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Gallus gallus 15904 R-GGA-5690042 https://reactome.org/PathwayBrowser/#/R-GGA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 15904 R-GGA-5690043 https://reactome.org/PathwayBrowser/#/R-GGA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 15904 R-GGA-5690066 https://reactome.org/PathwayBrowser/#/R-GGA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 15904 R-GGA-8980228 https://reactome.org/PathwayBrowser/#/R-GGA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Gallus gallus 15904 R-HSA-170026 https://reactome.org/PathwayBrowser/#/R-HSA-170026 Protons are translocated from the intermembrane space to the matrix TAS Homo sapiens 15904 R-HSA-174757 https://reactome.org/PathwayBrowser/#/R-HSA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols TAS Homo sapiens 15904 R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 15904 R-HSA-192422 https://reactome.org/PathwayBrowser/#/R-HSA-192422 Digestion of triacylglycerols by extracellular PTL:colipase TAS Homo sapiens 15904 R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 15904 R-HSA-192430 https://reactome.org/PathwayBrowser/#/R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 15904 R-HSA-192434 https://reactome.org/PathwayBrowser/#/R-HSA-192434 Digestion of diacylglycerols by extracellular PTL:colipase TAS Homo sapiens 15904 R-HSA-192475 https://reactome.org/PathwayBrowser/#/R-HSA-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 TAS Homo sapiens 15904 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 15904 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 15904 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 15904 R-HSA-382575 https://reactome.org/PathwayBrowser/#/R-HSA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix TAS Homo sapiens 15904 R-HSA-5684043 https://reactome.org/PathwayBrowser/#/R-HSA-5684043 Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix TAS Homo sapiens 15904 R-HSA-5690042 https://reactome.org/PathwayBrowser/#/R-HSA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 15904 R-HSA-5690043 https://reactome.org/PathwayBrowser/#/R-HSA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 15904 R-HSA-5690066 https://reactome.org/PathwayBrowser/#/R-HSA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 15904 R-HSA-8979996 https://reactome.org/PathwayBrowser/#/R-HSA-8979996 LIPs hydrolyze TG to DAG and LCFA TAS Homo sapiens 15904 R-HSA-8980228 https://reactome.org/PathwayBrowser/#/R-HSA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA TAS Homo sapiens 15904 R-MMU-170026 https://reactome.org/PathwayBrowser/#/R-MMU-170026 Protons are translocated from the intermembrane space to the matrix IEA Mus musculus 15904 R-MMU-174757 https://reactome.org/PathwayBrowser/#/R-MMU-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Mus musculus 15904 R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 15904 R-MMU-192422 https://reactome.org/PathwayBrowser/#/R-MMU-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Mus musculus 15904 R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 15904 R-MMU-192430 https://reactome.org/PathwayBrowser/#/R-MMU-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 15904 R-MMU-192434 https://reactome.org/PathwayBrowser/#/R-MMU-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Mus musculus 15904 R-MMU-192475 https://reactome.org/PathwayBrowser/#/R-MMU-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Mus musculus 15904 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 15904 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 15904 R-MMU-382575 https://reactome.org/PathwayBrowser/#/R-MMU-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Mus musculus 15904 R-MMU-5690042 https://reactome.org/PathwayBrowser/#/R-MMU-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 15904 R-MMU-5690043 https://reactome.org/PathwayBrowser/#/R-MMU-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 15904 R-MMU-5690066 https://reactome.org/PathwayBrowser/#/R-MMU-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 15904 R-MMU-8979996 https://reactome.org/PathwayBrowser/#/R-MMU-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Mus musculus 15904 R-MMU-8980228 https://reactome.org/PathwayBrowser/#/R-MMU-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Mus musculus 15904 R-MTU-9635480 https://reactome.org/PathwayBrowser/#/R-MTU-9635480 FadD26, FadD28 transfer adenylyl group to a LCFA TAS Mycobacterium tuberculosis 15904 R-PFA-5690066 https://reactome.org/PathwayBrowser/#/R-PFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Plasmodium falciparum 15904 R-PFA-8979996 https://reactome.org/PathwayBrowser/#/R-PFA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Plasmodium falciparum 15904 R-RNO-163407 https://reactome.org/PathwayBrowser/#/R-RNO-163407 cholesterol ester + H2O -> cholesterol + fatty acid TAS Rattus norvegicus 15904 R-RNO-163439 https://reactome.org/PathwayBrowser/#/R-RNO-163439 2-acylglycerol + H2O -> glycerol + fatty acid TAS Rattus norvegicus 15904 R-RNO-163440 https://reactome.org/PathwayBrowser/#/R-RNO-163440 diacylglycerol + H2O -> 2-acylglycerol + fatty acid TAS Rattus norvegicus 15904 R-RNO-163515 https://reactome.org/PathwayBrowser/#/R-RNO-163515 triacylglycerol + H2O -> diacylglycerol + fatty acid TAS Rattus norvegicus 15904 R-RNO-170026 https://reactome.org/PathwayBrowser/#/R-RNO-170026 Protons are translocated from the intermembrane space to the matrix IEA Rattus norvegicus 15904 R-RNO-174757 https://reactome.org/PathwayBrowser/#/R-RNO-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Rattus norvegicus 15904 R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 15904 R-RNO-192422 https://reactome.org/PathwayBrowser/#/R-RNO-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Rattus norvegicus 15904 R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 15904 R-RNO-192430 https://reactome.org/PathwayBrowser/#/R-RNO-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 15904 R-RNO-192434 https://reactome.org/PathwayBrowser/#/R-RNO-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Rattus norvegicus 15904 R-RNO-192475 https://reactome.org/PathwayBrowser/#/R-RNO-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Rattus norvegicus 15904 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 15904 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 15904 R-RNO-382575 https://reactome.org/PathwayBrowser/#/R-RNO-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Rattus norvegicus 15904 R-RNO-5690042 https://reactome.org/PathwayBrowser/#/R-RNO-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 15904 R-RNO-5690043 https://reactome.org/PathwayBrowser/#/R-RNO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 15904 R-RNO-5690066 https://reactome.org/PathwayBrowser/#/R-RNO-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 15904 R-RNO-8979996 https://reactome.org/PathwayBrowser/#/R-RNO-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Rattus norvegicus 15904 R-RNO-8980228 https://reactome.org/PathwayBrowser/#/R-RNO-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Rattus norvegicus 15904 R-SCE-382575 https://reactome.org/PathwayBrowser/#/R-SCE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Saccharomyces cerevisiae 15904 R-SCE-5690042 https://reactome.org/PathwayBrowser/#/R-SCE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Saccharomyces cerevisiae 15904 R-SCE-8979996 https://reactome.org/PathwayBrowser/#/R-SCE-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Saccharomyces cerevisiae 15904 R-SPO-5690043 https://reactome.org/PathwayBrowser/#/R-SPO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Schizosaccharomyces pombe 15904 R-SPO-8979996 https://reactome.org/PathwayBrowser/#/R-SPO-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Schizosaccharomyces pombe 15904 R-SSC-170026 https://reactome.org/PathwayBrowser/#/R-SSC-170026 Protons are translocated from the intermembrane space to the matrix IEA Sus scrofa 15904 R-SSC-174757 https://reactome.org/PathwayBrowser/#/R-SSC-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Sus scrofa 15904 R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 15904 R-SSC-192422 https://reactome.org/PathwayBrowser/#/R-SSC-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Sus scrofa 15904 R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 15904 R-SSC-192430 https://reactome.org/PathwayBrowser/#/R-SSC-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 15904 R-SSC-192434 https://reactome.org/PathwayBrowser/#/R-SSC-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Sus scrofa 15904 R-SSC-192475 https://reactome.org/PathwayBrowser/#/R-SSC-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Sus scrofa 15904 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 15904 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 15904 R-SSC-382575 https://reactome.org/PathwayBrowser/#/R-SSC-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Sus scrofa 15904 R-SSC-5690042 https://reactome.org/PathwayBrowser/#/R-SSC-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 15904 R-SSC-5690043 https://reactome.org/PathwayBrowser/#/R-SSC-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 15904 R-SSC-5690066 https://reactome.org/PathwayBrowser/#/R-SSC-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 15904 R-SSC-8980228 https://reactome.org/PathwayBrowser/#/R-SSC-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Sus scrofa 15904 R-XTR-170026 https://reactome.org/PathwayBrowser/#/R-XTR-170026 Protons are translocated from the intermembrane space to the matrix IEA Xenopus tropicalis 15904 R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 15904 R-XTR-192422 https://reactome.org/PathwayBrowser/#/R-XTR-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis 15904 R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 15904 R-XTR-192430 https://reactome.org/PathwayBrowser/#/R-XTR-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 15904 R-XTR-192434 https://reactome.org/PathwayBrowser/#/R-XTR-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis 15904 R-XTR-382575 https://reactome.org/PathwayBrowser/#/R-XTR-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Xenopus tropicalis 15904 R-XTR-5690042 https://reactome.org/PathwayBrowser/#/R-XTR-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 15904 R-XTR-5690043 https://reactome.org/PathwayBrowser/#/R-XTR-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 15904 R-XTR-5690066 https://reactome.org/PathwayBrowser/#/R-XTR-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 15904 R-XTR-8980228 https://reactome.org/PathwayBrowser/#/R-XTR-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Xenopus tropicalis 15915 R-BTA-9645394 https://reactome.org/PathwayBrowser/#/R-BTA-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation IEA Bos taurus 15915 R-BTA-9645406 https://reactome.org/PathwayBrowser/#/R-BTA-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) IEA Bos taurus 15915 R-BTA-9645414 https://reactome.org/PathwayBrowser/#/R-BTA-9645414 Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer IEA Bos taurus 15915 R-BTA-9645428 https://reactome.org/PathwayBrowser/#/R-BTA-9645428 ALPK1 binds ADP-heptose IEA Bos taurus 15915 R-BTA-9645442 https://reactome.org/PathwayBrowser/#/R-BTA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Bos taurus 15915 R-BTA-9645481 https://reactome.org/PathwayBrowser/#/R-BTA-9645481 TIFA oligomerization IEA Bos taurus 15915 R-BTA-9645501 https://reactome.org/PathwayBrowser/#/R-BTA-9645501 TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex IEA Bos taurus 15915 R-BTA-9645520 https://reactome.org/PathwayBrowser/#/R-BTA-9645520 ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 IEA Bos taurus 15915 R-BTA-9645524 https://reactome.org/PathwayBrowser/#/R-BTA-9645524 ALPK1:ADP-heptose binds TIFA IEA Bos taurus 15915 R-BTA-9645535 https://reactome.org/PathwayBrowser/#/R-BTA-9645535 ALPK1 phosphorylates TIFA IEA Bos taurus 15915 R-CFA-9645394 https://reactome.org/PathwayBrowser/#/R-CFA-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation IEA Canis familiaris 15915 R-CFA-9645406 https://reactome.org/PathwayBrowser/#/R-CFA-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) IEA Canis familiaris 15915 R-CFA-9645414 https://reactome.org/PathwayBrowser/#/R-CFA-9645414 Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer IEA Canis familiaris 15915 R-CFA-9645428 https://reactome.org/PathwayBrowser/#/R-CFA-9645428 ALPK1 binds ADP-heptose IEA Canis familiaris 15915 R-CFA-9645442 https://reactome.org/PathwayBrowser/#/R-CFA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Canis familiaris 15915 R-CFA-9645481 https://reactome.org/PathwayBrowser/#/R-CFA-9645481 TIFA oligomerization IEA Canis familiaris 15915 R-CFA-9645501 https://reactome.org/PathwayBrowser/#/R-CFA-9645501 TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex IEA Canis familiaris 15915 R-CFA-9645520 https://reactome.org/PathwayBrowser/#/R-CFA-9645520 ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 IEA Canis familiaris 15915 R-CFA-9645524 https://reactome.org/PathwayBrowser/#/R-CFA-9645524 ALPK1:ADP-heptose binds TIFA IEA Canis familiaris 15915 R-CFA-9645535 https://reactome.org/PathwayBrowser/#/R-CFA-9645535 ALPK1 phosphorylates TIFA IEA Canis familiaris 15915 R-CFA-9758604 https://reactome.org/PathwayBrowser/#/R-CFA-9758604 Ubiquitination of IKBKG by TRAF6 IEA Canis familiaris 15915 R-GGA-9645394 https://reactome.org/PathwayBrowser/#/R-GGA-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation IEA Gallus gallus 15915 R-GGA-9645406 https://reactome.org/PathwayBrowser/#/R-GGA-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) IEA Gallus gallus 15915 R-GGA-9645414 https://reactome.org/PathwayBrowser/#/R-GGA-9645414 Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer IEA Gallus gallus 15915 R-GGA-9645428 https://reactome.org/PathwayBrowser/#/R-GGA-9645428 ALPK1 binds ADP-heptose IEA Gallus gallus 15915 R-GGA-9645442 https://reactome.org/PathwayBrowser/#/R-GGA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Gallus gallus 15915 R-GGA-9645481 https://reactome.org/PathwayBrowser/#/R-GGA-9645481 TIFA oligomerization IEA Gallus gallus 15915 R-GGA-9645501 https://reactome.org/PathwayBrowser/#/R-GGA-9645501 TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex IEA Gallus gallus 15915 R-GGA-9645520 https://reactome.org/PathwayBrowser/#/R-GGA-9645520 ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 IEA Gallus gallus 15915 R-GGA-9645524 https://reactome.org/PathwayBrowser/#/R-GGA-9645524 ALPK1:ADP-heptose binds TIFA IEA Gallus gallus 15915 R-GGA-9645535 https://reactome.org/PathwayBrowser/#/R-GGA-9645535 ALPK1 phosphorylates TIFA IEA Gallus gallus 15915 R-HSA-9645394 https://reactome.org/PathwayBrowser/#/R-HSA-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation TAS Homo sapiens 15915 R-HSA-9645406 https://reactome.org/PathwayBrowser/#/R-HSA-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) TAS Homo sapiens 15915 R-HSA-9645414 https://reactome.org/PathwayBrowser/#/R-HSA-9645414 Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer TAS Homo sapiens 15915 R-HSA-9645428 https://reactome.org/PathwayBrowser/#/R-HSA-9645428 ALPK1 binds ADP-heptose TAS Homo sapiens 15915 R-HSA-9645442 https://reactome.org/PathwayBrowser/#/R-HSA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex TAS Homo sapiens 15915 R-HSA-9645481 https://reactome.org/PathwayBrowser/#/R-HSA-9645481 TIFA oligomerization TAS Homo sapiens 15915 R-HSA-9645501 https://reactome.org/PathwayBrowser/#/R-HSA-9645501 TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex TAS Homo sapiens 15915 R-HSA-9645520 https://reactome.org/PathwayBrowser/#/R-HSA-9645520 ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 TAS Homo sapiens 15915 R-HSA-9645524 https://reactome.org/PathwayBrowser/#/R-HSA-9645524 ALPK1:ADP-heptose binds TIFA TAS Homo sapiens 15915 R-HSA-9645535 https://reactome.org/PathwayBrowser/#/R-HSA-9645535 ALPK1 phosphorylates TIFA TAS Homo sapiens 15915 R-HSA-9758604 https://reactome.org/PathwayBrowser/#/R-HSA-9758604 Ubiquitination of IKBKG by TRAF6 TAS Homo sapiens 15915 R-MMU-9645394 https://reactome.org/PathwayBrowser/#/R-MMU-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation IEA Mus musculus 15915 R-MMU-9645406 https://reactome.org/PathwayBrowser/#/R-MMU-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) IEA Mus musculus 15915 R-MMU-9645414 https://reactome.org/PathwayBrowser/#/R-MMU-9645414 Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer IEA Mus musculus 15915 R-MMU-9645428 https://reactome.org/PathwayBrowser/#/R-MMU-9645428 ALPK1 binds ADP-heptose IEA Mus musculus 15915 R-MMU-9645442 https://reactome.org/PathwayBrowser/#/R-MMU-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Mus musculus 15915 R-MMU-9645481 https://reactome.org/PathwayBrowser/#/R-MMU-9645481 TIFA oligomerization IEA Mus musculus 15915 R-MMU-9645501 https://reactome.org/PathwayBrowser/#/R-MMU-9645501 TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex IEA Mus musculus 15915 R-MMU-9645520 https://reactome.org/PathwayBrowser/#/R-MMU-9645520 ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 IEA Mus musculus 15915 R-MMU-9645524 https://reactome.org/PathwayBrowser/#/R-MMU-9645524 ALPK1:ADP-heptose binds TIFA IEA Mus musculus 15915 R-MMU-9645535 https://reactome.org/PathwayBrowser/#/R-MMU-9645535 ALPK1 phosphorylates TIFA IEA Mus musculus 15915 R-MMU-9758604 https://reactome.org/PathwayBrowser/#/R-MMU-9758604 Ubiquitination of IKBKG by TRAF6 IEA Mus musculus 15915 R-RNO-9645394 https://reactome.org/PathwayBrowser/#/R-RNO-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation IEA Rattus norvegicus 15915 R-RNO-9645406 https://reactome.org/PathwayBrowser/#/R-RNO-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) IEA Rattus norvegicus 15915 R-RNO-9645414 https://reactome.org/PathwayBrowser/#/R-RNO-9645414 Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer IEA Rattus norvegicus 15915 R-RNO-9645428 https://reactome.org/PathwayBrowser/#/R-RNO-9645428 ALPK1 binds ADP-heptose IEA Rattus norvegicus 15915 R-RNO-9645442 https://reactome.org/PathwayBrowser/#/R-RNO-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Rattus norvegicus 15915 R-RNO-9645481 https://reactome.org/PathwayBrowser/#/R-RNO-9645481 TIFA oligomerization IEA Rattus norvegicus 15915 R-RNO-9645501 https://reactome.org/PathwayBrowser/#/R-RNO-9645501 TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex IEA Rattus norvegicus 15915 R-RNO-9645520 https://reactome.org/PathwayBrowser/#/R-RNO-9645520 ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 IEA Rattus norvegicus 15915 R-RNO-9645524 https://reactome.org/PathwayBrowser/#/R-RNO-9645524 ALPK1:ADP-heptose binds TIFA IEA Rattus norvegicus 15915 R-RNO-9645535 https://reactome.org/PathwayBrowser/#/R-RNO-9645535 ALPK1 phosphorylates TIFA IEA Rattus norvegicus 15915 R-SSC-9645394 https://reactome.org/PathwayBrowser/#/R-SSC-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation IEA Sus scrofa 15915 R-SSC-9645406 https://reactome.org/PathwayBrowser/#/R-SSC-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) IEA Sus scrofa 15915 R-SSC-9645414 https://reactome.org/PathwayBrowser/#/R-SSC-9645414 Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer IEA Sus scrofa 15915 R-SSC-9645428 https://reactome.org/PathwayBrowser/#/R-SSC-9645428 ALPK1 binds ADP-heptose IEA Sus scrofa 15915 R-SSC-9645442 https://reactome.org/PathwayBrowser/#/R-SSC-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Sus scrofa 15915 R-SSC-9645481 https://reactome.org/PathwayBrowser/#/R-SSC-9645481 TIFA oligomerization IEA Sus scrofa 15915 R-SSC-9645501 https://reactome.org/PathwayBrowser/#/R-SSC-9645501 TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex IEA Sus scrofa 15915 R-SSC-9645520 https://reactome.org/PathwayBrowser/#/R-SSC-9645520 ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 IEA Sus scrofa 15915 R-SSC-9645524 https://reactome.org/PathwayBrowser/#/R-SSC-9645524 ALPK1:ADP-heptose binds TIFA IEA Sus scrofa 15915 R-SSC-9645535 https://reactome.org/PathwayBrowser/#/R-SSC-9645535 ALPK1 phosphorylates TIFA IEA Sus scrofa 15915 R-SSC-9758604 https://reactome.org/PathwayBrowser/#/R-SSC-9758604 Ubiquitination of IKBKG by TRAF6 IEA Sus scrofa 15915 R-XTR-9645394 https://reactome.org/PathwayBrowser/#/R-XTR-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation IEA Xenopus tropicalis 15915 R-XTR-9645406 https://reactome.org/PathwayBrowser/#/R-XTR-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) IEA Xenopus tropicalis 15915 R-XTR-9645414 https://reactome.org/PathwayBrowser/#/R-XTR-9645414 Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer IEA Xenopus tropicalis 15915 R-XTR-9645428 https://reactome.org/PathwayBrowser/#/R-XTR-9645428 ALPK1 binds ADP-heptose IEA Xenopus tropicalis 15915 R-XTR-9645442 https://reactome.org/PathwayBrowser/#/R-XTR-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Xenopus tropicalis 15915 R-XTR-9645481 https://reactome.org/PathwayBrowser/#/R-XTR-9645481 TIFA oligomerization IEA Xenopus tropicalis 15915 R-XTR-9645501 https://reactome.org/PathwayBrowser/#/R-XTR-9645501 TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex IEA Xenopus tropicalis 15915 R-XTR-9645520 https://reactome.org/PathwayBrowser/#/R-XTR-9645520 ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 IEA Xenopus tropicalis 15915 R-XTR-9645524 https://reactome.org/PathwayBrowser/#/R-XTR-9645524 ALPK1:ADP-heptose binds TIFA IEA Xenopus tropicalis 15915 R-XTR-9645535 https://reactome.org/PathwayBrowser/#/R-XTR-9645535 ALPK1 phosphorylates TIFA IEA Xenopus tropicalis 15927 R-BTA-8869627 https://reactome.org/PathwayBrowser/#/R-BTA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Bos taurus 15927 R-BTA-8869633 https://reactome.org/PathwayBrowser/#/R-BTA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Bos taurus 15927 R-BTA-8936519 https://reactome.org/PathwayBrowser/#/R-BTA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Bos taurus 15927 R-BTA-8940074 https://reactome.org/PathwayBrowser/#/R-BTA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Bos taurus 15927 R-CFA-8869633 https://reactome.org/PathwayBrowser/#/R-CFA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Canis familiaris 15927 R-CFA-8936519 https://reactome.org/PathwayBrowser/#/R-CFA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Canis familiaris 15927 R-CFA-8940074 https://reactome.org/PathwayBrowser/#/R-CFA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Canis familiaris 15927 R-DDI-8869627 https://reactome.org/PathwayBrowser/#/R-DDI-8869627 NMRK2 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 15927 R-DDI-8869633 https://reactome.org/PathwayBrowser/#/R-DDI-8869633 NMRK1 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 15927 R-DME-8869627 https://reactome.org/PathwayBrowser/#/R-DME-8869627 NMRK2 phosphorylates NR to yield NMN IEA Drosophila melanogaster 15927 R-DME-8869633 https://reactome.org/PathwayBrowser/#/R-DME-8869633 NMRK1 phosphorylates NR to yield NMN IEA Drosophila melanogaster 15927 R-DME-8940074 https://reactome.org/PathwayBrowser/#/R-DME-8940074 NT5E:Zn2+ hydrolyses NMN IEA Drosophila melanogaster 15927 R-DRE-8869627 https://reactome.org/PathwayBrowser/#/R-DRE-8869627 NMRK2 phosphorylates NR to yield NMN IEA Danio rerio 15927 R-DRE-8940074 https://reactome.org/PathwayBrowser/#/R-DRE-8940074 NT5E:Zn2+ hydrolyses NMN IEA Danio rerio 15927 R-GGA-8869627 https://reactome.org/PathwayBrowser/#/R-GGA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Gallus gallus 15927 R-GGA-8869633 https://reactome.org/PathwayBrowser/#/R-GGA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Gallus gallus 15927 R-GGA-8936519 https://reactome.org/PathwayBrowser/#/R-GGA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Gallus gallus 15927 R-GGA-8940074 https://reactome.org/PathwayBrowser/#/R-GGA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Gallus gallus 15927 R-HSA-8869627 https://reactome.org/PathwayBrowser/#/R-HSA-8869627 NMRK2 phosphorylates NR to yield NMN TAS Homo sapiens 15927 R-HSA-8869633 https://reactome.org/PathwayBrowser/#/R-HSA-8869633 NMRK1 phosphorylates NR to yield NMN TAS Homo sapiens 15927 R-HSA-8936519 https://reactome.org/PathwayBrowser/#/R-HSA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones TAS Homo sapiens 15927 R-HSA-8940074 https://reactome.org/PathwayBrowser/#/R-HSA-8940074 NT5E:Zn2+ hydrolyses NMN TAS Homo sapiens 15927 R-MMU-8869627 https://reactome.org/PathwayBrowser/#/R-MMU-8869627 NMRK2 phosphorylates NR to yield NMN IEA Mus musculus 15927 R-MMU-8869633 https://reactome.org/PathwayBrowser/#/R-MMU-8869633 NMRK1 phosphorylates NR to yield NMN IEA Mus musculus 15927 R-MMU-8936519 https://reactome.org/PathwayBrowser/#/R-MMU-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Mus musculus 15927 R-MMU-8940074 https://reactome.org/PathwayBrowser/#/R-MMU-8940074 NT5E:Zn2+ hydrolyses NMN IEA Mus musculus 15927 R-RNO-8869633 https://reactome.org/PathwayBrowser/#/R-RNO-8869633 NMRK1 phosphorylates NR to yield NMN IEA Rattus norvegicus 15927 R-RNO-8936519 https://reactome.org/PathwayBrowser/#/R-RNO-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Rattus norvegicus 15927 R-RNO-8940074 https://reactome.org/PathwayBrowser/#/R-RNO-8940074 NT5E:Zn2+ hydrolyses NMN IEA Rattus norvegicus 15927 R-SSC-8869627 https://reactome.org/PathwayBrowser/#/R-SSC-8869627 NMRK2 phosphorylates NR to yield NMN IEA Sus scrofa 15927 R-SSC-8869633 https://reactome.org/PathwayBrowser/#/R-SSC-8869633 NMRK1 phosphorylates NR to yield NMN IEA Sus scrofa 15927 R-SSC-8936519 https://reactome.org/PathwayBrowser/#/R-SSC-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Sus scrofa 15927 R-SSC-8940074 https://reactome.org/PathwayBrowser/#/R-SSC-8940074 NT5E:Zn2+ hydrolyses NMN IEA Sus scrofa 15927 R-XTR-8936519 https://reactome.org/PathwayBrowser/#/R-XTR-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Xenopus tropicalis 15927 R-XTR-8940074 https://reactome.org/PathwayBrowser/#/R-XTR-8940074 NT5E:Zn2+ hydrolyses NMN IEA Xenopus tropicalis 15936 R-BTA-2090079 https://reactome.org/PathwayBrowser/#/R-BTA-2090079 GLB1 hydrolyses linker chain(2) IEA Bos taurus 15936 R-CEL-2090079 https://reactome.org/PathwayBrowser/#/R-CEL-2090079 GLB1 hydrolyses linker chain(2) IEA Caenorhabditis elegans 15936 R-CFA-2090079 https://reactome.org/PathwayBrowser/#/R-CFA-2090079 GLB1 hydrolyses linker chain(2) IEA Canis familiaris 15936 R-DDI-2090079 https://reactome.org/PathwayBrowser/#/R-DDI-2090079 GLB1 hydrolyses linker chain(2) IEA Dictyostelium discoideum 15936 R-DME-2090079 https://reactome.org/PathwayBrowser/#/R-DME-2090079 GLB1 hydrolyses linker chain(2) IEA Drosophila melanogaster 15936 R-GGA-2090079 https://reactome.org/PathwayBrowser/#/R-GGA-2090079 GLB1 hydrolyses linker chain(2) IEA Gallus gallus 15936 R-HSA-2090079 https://reactome.org/PathwayBrowser/#/R-HSA-2090079 GLB1 hydrolyses linker chain(2) TAS Homo sapiens 15936 R-MMU-2090079 https://reactome.org/PathwayBrowser/#/R-MMU-2090079 GLB1 hydrolyses linker chain(2) IEA Mus musculus 15936 R-RNO-2090079 https://reactome.org/PathwayBrowser/#/R-RNO-2090079 GLB1 hydrolyses linker chain(2) IEA Rattus norvegicus 15936 R-SSC-2090079 https://reactome.org/PathwayBrowser/#/R-SSC-2090079 GLB1 hydrolyses linker chain(2) IEA Sus scrofa 15936 R-XTR-2090079 https://reactome.org/PathwayBrowser/#/R-XTR-2090079 GLB1 hydrolyses linker chain(2) IEA Xenopus tropicalis 15940 R-BTA-197186 https://reactome.org/PathwayBrowser/#/R-BTA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Bos taurus 15940 R-BTA-3296309 https://reactome.org/PathwayBrowser/#/R-BTA-3296309 HCAR3 binds HCAR3 ligands IEA Bos taurus 15940 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 15940 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Bos taurus 15940 R-BTA-444661 https://reactome.org/PathwayBrowser/#/R-BTA-444661 HCAR2 binds HCAR2 ligands IEA Bos taurus 15940 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 15940 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 15940 R-BTA-8876312 https://reactome.org/PathwayBrowser/#/R-BTA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Bos taurus 15940 R-CEL-197186 https://reactome.org/PathwayBrowser/#/R-CEL-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Caenorhabditis elegans 15940 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Caenorhabditis elegans 15940 R-CEL-8869603 https://reactome.org/PathwayBrowser/#/R-CEL-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Caenorhabditis elegans 15940 R-CEL-8876312 https://reactome.org/PathwayBrowser/#/R-CEL-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Caenorhabditis elegans 15940 R-CFA-197186 https://reactome.org/PathwayBrowser/#/R-CFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Canis familiaris 15940 R-CFA-3296309 https://reactome.org/PathwayBrowser/#/R-CFA-3296309 HCAR3 binds HCAR3 ligands IEA Canis familiaris 15940 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 15940 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Canis familiaris 15940 R-CFA-444661 https://reactome.org/PathwayBrowser/#/R-CFA-444661 HCAR2 binds HCAR2 ligands IEA Canis familiaris 15940 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 15940 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 15940 R-CFA-8869603 https://reactome.org/PathwayBrowser/#/R-CFA-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Canis familiaris 15940 R-CFA-8876312 https://reactome.org/PathwayBrowser/#/R-CFA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Canis familiaris 15940 R-DDI-197186 https://reactome.org/PathwayBrowser/#/R-DDI-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Dictyostelium discoideum 15940 R-DME-197186 https://reactome.org/PathwayBrowser/#/R-DME-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Drosophila melanogaster 15940 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Drosophila melanogaster 15940 R-DME-8869603 https://reactome.org/PathwayBrowser/#/R-DME-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Drosophila melanogaster 15940 R-DME-8876312 https://reactome.org/PathwayBrowser/#/R-DME-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Drosophila melanogaster 15940 R-DRE-197186 https://reactome.org/PathwayBrowser/#/R-DRE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Danio rerio 15940 R-DRE-3296309 https://reactome.org/PathwayBrowser/#/R-DRE-3296309 HCAR3 binds HCAR3 ligands IEA Danio rerio 15940 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 15940 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Danio rerio 15940 R-DRE-444661 https://reactome.org/PathwayBrowser/#/R-DRE-444661 HCAR2 binds HCAR2 ligands IEA Danio rerio 15940 R-DRE-8876312 https://reactome.org/PathwayBrowser/#/R-DRE-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Danio rerio 15940 R-GGA-197186 https://reactome.org/PathwayBrowser/#/R-GGA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Gallus gallus 15940 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Gallus gallus 15940 R-GGA-8869603 https://reactome.org/PathwayBrowser/#/R-GGA-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Gallus gallus 15940 R-GGA-8876312 https://reactome.org/PathwayBrowser/#/R-GGA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Gallus gallus 15940 R-HSA-197186 https://reactome.org/PathwayBrowser/#/R-HSA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN TAS Homo sapiens 15940 R-HSA-3296309 https://reactome.org/PathwayBrowser/#/R-HSA-3296309 HCAR3 binds HCAR3 ligands TAS Homo sapiens 15940 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 15940 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol TAS Homo sapiens 15940 R-HSA-444661 https://reactome.org/PathwayBrowser/#/R-HSA-444661 HCAR2 binds HCAR2 ligands TAS Homo sapiens 15940 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 15940 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 15940 R-HSA-8869603 https://reactome.org/PathwayBrowser/#/R-HSA-8869603 SLC22A13 transports NCA from extracellular region to cytosol TAS Homo sapiens 15940 R-HSA-8876312 https://reactome.org/PathwayBrowser/#/R-HSA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol TAS Homo sapiens 15940 R-MMU-197186 https://reactome.org/PathwayBrowser/#/R-MMU-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Mus musculus 15940 R-MMU-3296309 https://reactome.org/PathwayBrowser/#/R-MMU-3296309 HCAR3 binds HCAR3 ligands IEA Mus musculus 15940 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 15940 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Mus musculus 15940 R-MMU-444661 https://reactome.org/PathwayBrowser/#/R-MMU-444661 HCAR2 binds HCAR2 ligands IEA Mus musculus 15940 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 15940 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 15940 R-MMU-8869603 https://reactome.org/PathwayBrowser/#/R-MMU-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Mus musculus 15940 R-MMU-8876312 https://reactome.org/PathwayBrowser/#/R-MMU-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Mus musculus 15940 R-PFA-197186 https://reactome.org/PathwayBrowser/#/R-PFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Plasmodium falciparum 15940 R-RNO-197186 https://reactome.org/PathwayBrowser/#/R-RNO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Rattus norvegicus 15940 R-RNO-3296309 https://reactome.org/PathwayBrowser/#/R-RNO-3296309 HCAR3 binds HCAR3 ligands IEA Rattus norvegicus 15940 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 15940 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Rattus norvegicus 15940 R-RNO-444661 https://reactome.org/PathwayBrowser/#/R-RNO-444661 HCAR2 binds HCAR2 ligands IEA Rattus norvegicus 15940 R-RNO-8869603 https://reactome.org/PathwayBrowser/#/R-RNO-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Rattus norvegicus 15940 R-RNO-8876312 https://reactome.org/PathwayBrowser/#/R-RNO-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Rattus norvegicus 15940 R-SCE-197186 https://reactome.org/PathwayBrowser/#/R-SCE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Saccharomyces cerevisiae 15940 R-SPO-197186 https://reactome.org/PathwayBrowser/#/R-SPO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Schizosaccharomyces pombe 15940 R-SSC-197186 https://reactome.org/PathwayBrowser/#/R-SSC-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Sus scrofa 15940 R-SSC-3296309 https://reactome.org/PathwayBrowser/#/R-SSC-3296309 HCAR3 binds HCAR3 ligands IEA Sus scrofa 15940 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 15940 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Sus scrofa 15940 R-SSC-444661 https://reactome.org/PathwayBrowser/#/R-SSC-444661 HCAR2 binds HCAR2 ligands IEA Sus scrofa 15940 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 15940 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 15940 R-SSC-8869603 https://reactome.org/PathwayBrowser/#/R-SSC-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Sus scrofa 15940 R-SSC-8876312 https://reactome.org/PathwayBrowser/#/R-SSC-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Sus scrofa 15940 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Xenopus tropicalis 15940 R-XTR-8869603 https://reactome.org/PathwayBrowser/#/R-XTR-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Xenopus tropicalis 15940 R-XTR-8876312 https://reactome.org/PathwayBrowser/#/R-XTR-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Xenopus tropicalis 15956 R-BTA-199219 https://reactome.org/PathwayBrowser/#/R-BTA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Bos taurus 15956 R-BTA-2993447 https://reactome.org/PathwayBrowser/#/R-BTA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Bos taurus 15956 R-BTA-2993799 https://reactome.org/PathwayBrowser/#/R-BTA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Bos taurus 15956 R-BTA-2993802 https://reactome.org/PathwayBrowser/#/R-BTA-2993802 HLCS biotinylates PC:Mn2+ IEA Bos taurus 15956 R-BTA-2993814 https://reactome.org/PathwayBrowser/#/R-BTA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Bos taurus 15956 R-BTA-3076905 https://reactome.org/PathwayBrowser/#/R-BTA-3076905 Extracellular BTD hydrolyses BCTN IEA Bos taurus 15956 R-BTA-4167509 https://reactome.org/PathwayBrowser/#/R-BTA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Bos taurus 15956 R-BTA-4167511 https://reactome.org/PathwayBrowser/#/R-BTA-4167511 HLCS biotinylates ACACB IEA Bos taurus 15956 R-BTA-429581 https://reactome.org/PathwayBrowser/#/R-BTA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Bos taurus 15956 R-CEL-2993447 https://reactome.org/PathwayBrowser/#/R-CEL-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Caenorhabditis elegans 15956 R-CEL-2993799 https://reactome.org/PathwayBrowser/#/R-CEL-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Caenorhabditis elegans 15956 R-CEL-2993802 https://reactome.org/PathwayBrowser/#/R-CEL-2993802 HLCS biotinylates PC:Mn2+ IEA Caenorhabditis elegans 15956 R-CEL-2993814 https://reactome.org/PathwayBrowser/#/R-CEL-2993814 HLCS biotinylates ACACA:Mn2+ IEA Caenorhabditis elegans 15956 R-CEL-4167511 https://reactome.org/PathwayBrowser/#/R-CEL-4167511 HLCS biotinylates ACACB IEA Caenorhabditis elegans 15956 R-CFA-199219 https://reactome.org/PathwayBrowser/#/R-CFA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Canis familiaris 15956 R-CFA-2993447 https://reactome.org/PathwayBrowser/#/R-CFA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Canis familiaris 15956 R-CFA-2993799 https://reactome.org/PathwayBrowser/#/R-CFA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Canis familiaris 15956 R-CFA-2993802 https://reactome.org/PathwayBrowser/#/R-CFA-2993802 HLCS biotinylates PC:Mn2+ IEA Canis familiaris 15956 R-CFA-2993814 https://reactome.org/PathwayBrowser/#/R-CFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Canis familiaris 15956 R-CFA-3076905 https://reactome.org/PathwayBrowser/#/R-CFA-3076905 Extracellular BTD hydrolyses BCTN IEA Canis familiaris 15956 R-CFA-4167509 https://reactome.org/PathwayBrowser/#/R-CFA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Canis familiaris 15956 R-CFA-4167511 https://reactome.org/PathwayBrowser/#/R-CFA-4167511 HLCS biotinylates ACACB IEA Canis familiaris 15956 R-CFA-429581 https://reactome.org/PathwayBrowser/#/R-CFA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Canis familiaris 15956 R-DDI-2993447 https://reactome.org/PathwayBrowser/#/R-DDI-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Dictyostelium discoideum 15956 R-DDI-2993799 https://reactome.org/PathwayBrowser/#/R-DDI-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Dictyostelium discoideum 15956 R-DDI-2993814 https://reactome.org/PathwayBrowser/#/R-DDI-2993814 HLCS biotinylates ACACA:Mn2+ IEA Dictyostelium discoideum 15956 R-DDI-3076905 https://reactome.org/PathwayBrowser/#/R-DDI-3076905 Extracellular BTD hydrolyses BCTN IEA Dictyostelium discoideum 15956 R-DDI-4167509 https://reactome.org/PathwayBrowser/#/R-DDI-4167509 Mitochondrial BTD hydrolyses BCTN IEA Dictyostelium discoideum 15956 R-DDI-4167511 https://reactome.org/PathwayBrowser/#/R-DDI-4167511 HLCS biotinylates ACACB IEA Dictyostelium discoideum 15956 R-DME-2993799 https://reactome.org/PathwayBrowser/#/R-DME-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Drosophila melanogaster 15956 R-DME-2993802 https://reactome.org/PathwayBrowser/#/R-DME-2993802 HLCS biotinylates PC:Mn2+ IEA Drosophila melanogaster 15956 R-DME-2993814 https://reactome.org/PathwayBrowser/#/R-DME-2993814 HLCS biotinylates ACACA:Mn2+ IEA Drosophila melanogaster 15956 R-DME-3076905 https://reactome.org/PathwayBrowser/#/R-DME-3076905 Extracellular BTD hydrolyses BCTN IEA Drosophila melanogaster 15956 R-DME-4167509 https://reactome.org/PathwayBrowser/#/R-DME-4167509 Mitochondrial BTD hydrolyses BCTN IEA Drosophila melanogaster 15956 R-DME-4167511 https://reactome.org/PathwayBrowser/#/R-DME-4167511 HLCS biotinylates ACACB IEA Drosophila melanogaster 15956 R-DRE-199219 https://reactome.org/PathwayBrowser/#/R-DRE-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Danio rerio 15956 R-DRE-3076905 https://reactome.org/PathwayBrowser/#/R-DRE-3076905 Extracellular BTD hydrolyses BCTN IEA Danio rerio 15956 R-DRE-4167509 https://reactome.org/PathwayBrowser/#/R-DRE-4167509 Mitochondrial BTD hydrolyses BCTN IEA Danio rerio 15956 R-DRE-429581 https://reactome.org/PathwayBrowser/#/R-DRE-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Danio rerio 15956 R-GGA-199219 https://reactome.org/PathwayBrowser/#/R-GGA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Gallus gallus 15956 R-GGA-2993447 https://reactome.org/PathwayBrowser/#/R-GGA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Gallus gallus 15956 R-GGA-2993799 https://reactome.org/PathwayBrowser/#/R-GGA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Gallus gallus 15956 R-GGA-2993814 https://reactome.org/PathwayBrowser/#/R-GGA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Gallus gallus 15956 R-GGA-3076905 https://reactome.org/PathwayBrowser/#/R-GGA-3076905 Extracellular BTD hydrolyses BCTN IEA Gallus gallus 15956 R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 15956 R-GGA-4167509 https://reactome.org/PathwayBrowser/#/R-GGA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Gallus gallus 15956 R-GGA-429581 https://reactome.org/PathwayBrowser/#/R-GGA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Gallus gallus 15956 R-HSA-199219 https://reactome.org/PathwayBrowser/#/R-HSA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol TAS Homo sapiens 15956 R-HSA-2993447 https://reactome.org/PathwayBrowser/#/R-HSA-2993447 HLCS biotinylates 6x(PCCA:PCCB) TAS Homo sapiens 15956 R-HSA-2993799 https://reactome.org/PathwayBrowser/#/R-HSA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 TAS Homo sapiens 15956 R-HSA-2993802 https://reactome.org/PathwayBrowser/#/R-HSA-2993802 HLCS biotinylates PC:Mn2+ TAS Homo sapiens 15956 R-HSA-2993814 https://reactome.org/PathwayBrowser/#/R-HSA-2993814 HLCS biotinylates ACACA:Mn2+ TAS Homo sapiens 15956 R-HSA-3076905 https://reactome.org/PathwayBrowser/#/R-HSA-3076905 Extracellular BTD hydrolyses BCTN TAS Homo sapiens 15956 R-HSA-3323184 https://reactome.org/PathwayBrowser/#/R-HSA-3323184 Defective HLCS does not biotinylate ACACA:Mn2+ TAS Homo sapiens 15956 R-HSA-4167509 https://reactome.org/PathwayBrowser/#/R-HSA-4167509 Mitochondrial BTD hydrolyses BCTN TAS Homo sapiens 15956 R-HSA-4167511 https://reactome.org/PathwayBrowser/#/R-HSA-4167511 HLCS biotinylates ACACB TAS Homo sapiens 15956 R-HSA-429581 https://reactome.org/PathwayBrowser/#/R-HSA-429581 SLC5A6 transports vitamins from extracellular region to cytosol TAS Homo sapiens 15956 R-HSA-9035987 https://reactome.org/PathwayBrowser/#/R-HSA-9035987 Defective HLCS does not biotinylate 6xMCCC1:6xMCCC2 TAS Homo sapiens 15956 R-HSA-9035988 https://reactome.org/PathwayBrowser/#/R-HSA-9035988 Defective HLCS does not biotinylate PC:Mn2+ TAS Homo sapiens 15956 R-HSA-9035990 https://reactome.org/PathwayBrowser/#/R-HSA-9035990 Defective HLCS does not biotinylate 6x(PCCA:PCCB) TAS Homo sapiens 15956 R-MMU-199219 https://reactome.org/PathwayBrowser/#/R-MMU-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Mus musculus 15956 R-MMU-2993447 https://reactome.org/PathwayBrowser/#/R-MMU-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Mus musculus 15956 R-MMU-2993799 https://reactome.org/PathwayBrowser/#/R-MMU-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Mus musculus 15956 R-MMU-2993802 https://reactome.org/PathwayBrowser/#/R-MMU-2993802 HLCS biotinylates PC:Mn2+ IEA Mus musculus 15956 R-MMU-2993814 https://reactome.org/PathwayBrowser/#/R-MMU-2993814 HLCS biotinylates ACACA:Mn2+ IEA Mus musculus 15956 R-MMU-3076905 https://reactome.org/PathwayBrowser/#/R-MMU-3076905 Extracellular BTD hydrolyses BCTN IEA Mus musculus 15956 R-MMU-4167509 https://reactome.org/PathwayBrowser/#/R-MMU-4167509 Mitochondrial BTD hydrolyses BCTN IEA Mus musculus 15956 R-MMU-4167511 https://reactome.org/PathwayBrowser/#/R-MMU-4167511 HLCS biotinylates ACACB IEA Mus musculus 15956 R-MMU-429581 https://reactome.org/PathwayBrowser/#/R-MMU-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Mus musculus 15956 R-PFA-2993814 https://reactome.org/PathwayBrowser/#/R-PFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Plasmodium falciparum 15956 R-PFA-4167511 https://reactome.org/PathwayBrowser/#/R-PFA-4167511 HLCS biotinylates ACACB IEA Plasmodium falciparum 15956 R-RNO-199219 https://reactome.org/PathwayBrowser/#/R-RNO-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Rattus norvegicus 15956 R-RNO-2993447 https://reactome.org/PathwayBrowser/#/R-RNO-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Rattus norvegicus 15956 R-RNO-2993799 https://reactome.org/PathwayBrowser/#/R-RNO-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Rattus norvegicus 15956 R-RNO-2993802 https://reactome.org/PathwayBrowser/#/R-RNO-2993802 HLCS biotinylates PC:Mn2+ IEA Rattus norvegicus 15956 R-RNO-2993814 https://reactome.org/PathwayBrowser/#/R-RNO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Rattus norvegicus 15956 R-RNO-3076905 https://reactome.org/PathwayBrowser/#/R-RNO-3076905 Extracellular BTD hydrolyses BCTN IEA Rattus norvegicus 15956 R-RNO-4167509 https://reactome.org/PathwayBrowser/#/R-RNO-4167509 Mitochondrial BTD hydrolyses BCTN IEA Rattus norvegicus 15956 R-RNO-4167511 https://reactome.org/PathwayBrowser/#/R-RNO-4167511 HLCS biotinylates ACACB IEA Rattus norvegicus 15956 R-RNO-429581 https://reactome.org/PathwayBrowser/#/R-RNO-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Rattus norvegicus 15956 R-SCE-2993802 https://reactome.org/PathwayBrowser/#/R-SCE-2993802 HLCS biotinylates PC:Mn2+ IEA Saccharomyces cerevisiae 15956 R-SCE-2993814 https://reactome.org/PathwayBrowser/#/R-SCE-2993814 HLCS biotinylates ACACA:Mn2+ IEA Saccharomyces cerevisiae 15956 R-SCE-4167511 https://reactome.org/PathwayBrowser/#/R-SCE-4167511 HLCS biotinylates ACACB IEA Saccharomyces cerevisiae 15956 R-SPO-2993802 https://reactome.org/PathwayBrowser/#/R-SPO-2993802 HLCS biotinylates PC:Mn2+ IEA Schizosaccharomyces pombe 15956 R-SPO-2993814 https://reactome.org/PathwayBrowser/#/R-SPO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Schizosaccharomyces pombe 15956 R-SPO-4167511 https://reactome.org/PathwayBrowser/#/R-SPO-4167511 HLCS biotinylates ACACB IEA Schizosaccharomyces pombe 15956 R-SSC-199219 https://reactome.org/PathwayBrowser/#/R-SSC-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Sus scrofa 15956 R-SSC-2993447 https://reactome.org/PathwayBrowser/#/R-SSC-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Sus scrofa 15956 R-SSC-2993799 https://reactome.org/PathwayBrowser/#/R-SSC-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Sus scrofa 15956 R-SSC-2993802 https://reactome.org/PathwayBrowser/#/R-SSC-2993802 HLCS biotinylates PC:Mn2+ IEA Sus scrofa 15956 R-SSC-2993814 https://reactome.org/PathwayBrowser/#/R-SSC-2993814 HLCS biotinylates ACACA:Mn2+ IEA Sus scrofa 15956 R-SSC-3076905 https://reactome.org/PathwayBrowser/#/R-SSC-3076905 Extracellular BTD hydrolyses BCTN IEA Sus scrofa 15956 R-SSC-4167509 https://reactome.org/PathwayBrowser/#/R-SSC-4167509 Mitochondrial BTD hydrolyses BCTN IEA Sus scrofa 15956 R-SSC-4167511 https://reactome.org/PathwayBrowser/#/R-SSC-4167511 HLCS biotinylates ACACB IEA Sus scrofa 15956 R-SSC-429581 https://reactome.org/PathwayBrowser/#/R-SSC-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Sus scrofa 15956 R-XTR-199219 https://reactome.org/PathwayBrowser/#/R-XTR-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Xenopus tropicalis 15956 R-XTR-2993447 https://reactome.org/PathwayBrowser/#/R-XTR-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Xenopus tropicalis 15956 R-XTR-2993799 https://reactome.org/PathwayBrowser/#/R-XTR-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Xenopus tropicalis 15956 R-XTR-2993802 https://reactome.org/PathwayBrowser/#/R-XTR-2993802 HLCS biotinylates PC:Mn2+ IEA Xenopus tropicalis 15956 R-XTR-2993814 https://reactome.org/PathwayBrowser/#/R-XTR-2993814 HLCS biotinylates ACACA:Mn2+ IEA Xenopus tropicalis 15956 R-XTR-3076905 https://reactome.org/PathwayBrowser/#/R-XTR-3076905 Extracellular BTD hydrolyses BCTN IEA Xenopus tropicalis 15956 R-XTR-4167509 https://reactome.org/PathwayBrowser/#/R-XTR-4167509 Mitochondrial BTD hydrolyses BCTN IEA Xenopus tropicalis 15956 R-XTR-4167511 https://reactome.org/PathwayBrowser/#/R-XTR-4167511 HLCS biotinylates ACACB IEA Xenopus tropicalis 15956 R-XTR-429581 https://reactome.org/PathwayBrowser/#/R-XTR-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Xenopus tropicalis 15960 R-BTA-390291 https://reactome.org/PathwayBrowser/#/R-BTA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Bos taurus 15960 R-CEL-390291 https://reactome.org/PathwayBrowser/#/R-CEL-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Caenorhabditis elegans 15960 R-CFA-390291 https://reactome.org/PathwayBrowser/#/R-CFA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Canis familiaris 15960 R-DME-390291 https://reactome.org/PathwayBrowser/#/R-DME-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Drosophila melanogaster 15960 R-DRE-390291 https://reactome.org/PathwayBrowser/#/R-DRE-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Danio rerio 15960 R-GGA-390291 https://reactome.org/PathwayBrowser/#/R-GGA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Gallus gallus 15960 R-HSA-390291 https://reactome.org/PathwayBrowser/#/R-HSA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH TAS Homo sapiens 15960 R-MMU-390291 https://reactome.org/PathwayBrowser/#/R-MMU-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Mus musculus 15960 R-RNO-390291 https://reactome.org/PathwayBrowser/#/R-RNO-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Rattus norvegicus 15960 R-SSC-390291 https://reactome.org/PathwayBrowser/#/R-SSC-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Sus scrofa 15960 R-XTR-390291 https://reactome.org/PathwayBrowser/#/R-XTR-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Xenopus tropicalis 15967 R-HSA-2161612 https://reactome.org/PathwayBrowser/#/R-HSA-2161612 PGH2 is reduced to PGF2a by FAM213B IEA Homo sapiens 15967 R-MMU-2161718 https://reactome.org/PathwayBrowser/#/R-MMU-2161718 PGH2 is reduced to PGF2a by Fam213b TAS Mus musculus 15986 R-BTA-163090 https://reactome.org/PathwayBrowser/#/R-BTA-163090 Elongation Of The Telomeric Chromosome End IEA Bos taurus 15986 R-BTA-163096 https://reactome.org/PathwayBrowser/#/R-BTA-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End IEA Bos taurus 15986 R-BTA-163099 https://reactome.org/PathwayBrowser/#/R-BTA-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Bos taurus 15986 R-BTA-163120 https://reactome.org/PathwayBrowser/#/R-BTA-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Bos taurus 15986 R-BTA-164617 https://reactome.org/PathwayBrowser/#/R-BTA-164617 Elongation of Extended Telomeric Chromosome End IEA Bos taurus 15986 R-BTA-164620 https://reactome.org/PathwayBrowser/#/R-BTA-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Bos taurus 15986 R-BTA-174425 https://reactome.org/PathwayBrowser/#/R-BTA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Bos taurus 15986 R-BTA-174427 https://reactome.org/PathwayBrowser/#/R-BTA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Bos taurus 15986 R-BTA-174438 https://reactome.org/PathwayBrowser/#/R-BTA-174438 Formation of the Flap Intermediate on the C-strand IEA Bos taurus 15986 R-BTA-174439 https://reactome.org/PathwayBrowser/#/R-BTA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Bos taurus 15986 R-BTA-174441 https://reactome.org/PathwayBrowser/#/R-BTA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Bos taurus 15986 R-BTA-174444 https://reactome.org/PathwayBrowser/#/R-BTA-174444 Formation of C-strand Okazaki fragments IEA Bos taurus 15986 R-BTA-174445 https://reactome.org/PathwayBrowser/#/R-BTA-174445 RPA binds to the Flap on the C-strand IEA Bos taurus 15986 R-BTA-174446 https://reactome.org/PathwayBrowser/#/R-BTA-174446 Removal of remaining Flap from the C-strand IEA Bos taurus 15986 R-BTA-174447 https://reactome.org/PathwayBrowser/#/R-BTA-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Bos taurus 15986 R-BTA-174448 https://reactome.org/PathwayBrowser/#/R-BTA-174448 Formation of Processive Complex on the C-strand of the telomere IEA Bos taurus 15986 R-BTA-174451 https://reactome.org/PathwayBrowser/#/R-BTA-174451 Recruitment of DNA2 endonuclease to the C strand IEA Bos taurus 15986 R-BTA-174452 https://reactome.org/PathwayBrowser/#/R-BTA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Bos taurus 15986 R-BTA-174456 https://reactome.org/PathwayBrowser/#/R-BTA-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Bos taurus 15986 R-BTA-176700 https://reactome.org/PathwayBrowser/#/R-BTA-176700 Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure IEA Bos taurus 15986 R-BTA-176702 https://reactome.org/PathwayBrowser/#/R-BTA-176702 Disassociation of Processive Complex and Completed Telomere End IEA Bos taurus 15986 R-BTA-181450 https://reactome.org/PathwayBrowser/#/R-BTA-181450 Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure IEA Bos taurus 15986 R-BTA-9668597 https://reactome.org/PathwayBrowser/#/R-BTA-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Bos taurus 15986 R-BTA-9686521 https://reactome.org/PathwayBrowser/#/R-BTA-9686521 CDK2:CCNA phosphorylates TERF2 IEA Bos taurus 15986 R-BTA-9686524 https://reactome.org/PathwayBrowser/#/R-BTA-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Bos taurus 15986 R-CFA-163090 https://reactome.org/PathwayBrowser/#/R-CFA-163090 Elongation Of The Telomeric Chromosome End IEA Canis familiaris 15986 R-CFA-163096 https://reactome.org/PathwayBrowser/#/R-CFA-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End IEA Canis familiaris 15986 R-CFA-163099 https://reactome.org/PathwayBrowser/#/R-CFA-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Canis familiaris 15986 R-CFA-164617 https://reactome.org/PathwayBrowser/#/R-CFA-164617 Elongation of Extended Telomeric Chromosome End IEA Canis familiaris 15986 R-CFA-164620 https://reactome.org/PathwayBrowser/#/R-CFA-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Canis familiaris 15986 R-CFA-174425 https://reactome.org/PathwayBrowser/#/R-CFA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Canis familiaris 15986 R-CFA-174427 https://reactome.org/PathwayBrowser/#/R-CFA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Canis familiaris 15986 R-CFA-174438 https://reactome.org/PathwayBrowser/#/R-CFA-174438 Formation of the Flap Intermediate on the C-strand IEA Canis familiaris 15986 R-CFA-174439 https://reactome.org/PathwayBrowser/#/R-CFA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Canis familiaris 15986 R-CFA-174441 https://reactome.org/PathwayBrowser/#/R-CFA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Canis familiaris 15986 R-CFA-174444 https://reactome.org/PathwayBrowser/#/R-CFA-174444 Formation of C-strand Okazaki fragments IEA Canis familiaris 15986 R-CFA-174445 https://reactome.org/PathwayBrowser/#/R-CFA-174445 RPA binds to the Flap on the C-strand IEA Canis familiaris 15986 R-CFA-174446 https://reactome.org/PathwayBrowser/#/R-CFA-174446 Removal of remaining Flap from the C-strand IEA Canis familiaris 15986 R-CFA-174447 https://reactome.org/PathwayBrowser/#/R-CFA-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Canis familiaris 15986 R-CFA-174448 https://reactome.org/PathwayBrowser/#/R-CFA-174448 Formation of Processive Complex on the C-strand of the telomere IEA Canis familiaris 15986 R-CFA-174451 https://reactome.org/PathwayBrowser/#/R-CFA-174451 Recruitment of DNA2 endonuclease to the C strand IEA Canis familiaris 15986 R-CFA-174452 https://reactome.org/PathwayBrowser/#/R-CFA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Canis familiaris 15986 R-CFA-174456 https://reactome.org/PathwayBrowser/#/R-CFA-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Canis familiaris 15986 R-CFA-176702 https://reactome.org/PathwayBrowser/#/R-CFA-176702 Disassociation of Processive Complex and Completed Telomere End IEA Canis familiaris 15986 R-CFA-9668597 https://reactome.org/PathwayBrowser/#/R-CFA-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Canis familiaris 15986 R-CFA-9686521 https://reactome.org/PathwayBrowser/#/R-CFA-9686521 CDK2:CCNA phosphorylates TERF2 IEA Canis familiaris 15986 R-CFA-9686524 https://reactome.org/PathwayBrowser/#/R-CFA-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Canis familiaris 15986 R-GGA-163090 https://reactome.org/PathwayBrowser/#/R-GGA-163090 Elongation Of The Telomeric Chromosome End IEA Gallus gallus 15986 R-GGA-163099 https://reactome.org/PathwayBrowser/#/R-GGA-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Gallus gallus 15986 R-GGA-164617 https://reactome.org/PathwayBrowser/#/R-GGA-164617 Elongation of Extended Telomeric Chromosome End IEA Gallus gallus 15986 R-GGA-164620 https://reactome.org/PathwayBrowser/#/R-GGA-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Gallus gallus 15986 R-GGA-174425 https://reactome.org/PathwayBrowser/#/R-GGA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Gallus gallus 15986 R-GGA-174427 https://reactome.org/PathwayBrowser/#/R-GGA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Gallus gallus 15986 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus 15986 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus 15986 R-GGA-417077 https://reactome.org/PathwayBrowser/#/R-GGA-417077 Recruitment of telomerase RNP to a telomeric chromosome end IEA Gallus gallus 15986 R-GGA-417122 https://reactome.org/PathwayBrowser/#/R-GGA-417122 Elongation and translocation of the telomeric chromosome end IEA Gallus gallus 15986 R-GGA-417127 https://reactome.org/PathwayBrowser/#/R-GGA-417127 Elongation and translocation of the extended telomeric chromosome end IEA Gallus gallus 15986 R-GGA-418082 https://reactome.org/PathwayBrowser/#/R-GGA-418082 Dissociation of telomerase RNP from the extended chromosomal end IEA Gallus gallus 15986 R-GGA-418106 https://reactome.org/PathwayBrowser/#/R-GGA-418106 Packaging of telomere ends TAS Gallus gallus 15986 R-HSA-163090 https://reactome.org/PathwayBrowser/#/R-HSA-163090 Elongation Of The Telomeric Chromosome End TAS Homo sapiens 15986 R-HSA-163096 https://reactome.org/PathwayBrowser/#/R-HSA-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End TAS Homo sapiens 15986 R-HSA-163099 https://reactome.org/PathwayBrowser/#/R-HSA-163099 Alignment Of The RNA Template On The Telomeric Chromosome End TAS Homo sapiens 15986 R-HSA-163120 https://reactome.org/PathwayBrowser/#/R-HSA-163120 Disassociation of Telomerase RNP and the Chromosome End TAS Homo sapiens 15986 R-HSA-164617 https://reactome.org/PathwayBrowser/#/R-HSA-164617 Elongation of Extended Telomeric Chromosome End TAS Homo sapiens 15986 R-HSA-164620 https://reactome.org/PathwayBrowser/#/R-HSA-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End TAS Homo sapiens 15986 R-HSA-174425 https://reactome.org/PathwayBrowser/#/R-HSA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere TAS Homo sapiens 15986 R-HSA-174427 https://reactome.org/PathwayBrowser/#/R-HSA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere TAS Homo sapiens 15986 R-HSA-174438 https://reactome.org/PathwayBrowser/#/R-HSA-174438 Formation of the Flap Intermediate on the C-strand TAS Homo sapiens 15986 R-HSA-174439 https://reactome.org/PathwayBrowser/#/R-HSA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere TAS Homo sapiens 15986 R-HSA-174441 https://reactome.org/PathwayBrowser/#/R-HSA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand TAS Homo sapiens 15986 R-HSA-174444 https://reactome.org/PathwayBrowser/#/R-HSA-174444 Formation of C-strand Okazaki fragments TAS Homo sapiens 15986 R-HSA-174445 https://reactome.org/PathwayBrowser/#/R-HSA-174445 RPA binds to the Flap on the C-strand TAS Homo sapiens 15986 R-HSA-174446 https://reactome.org/PathwayBrowser/#/R-HSA-174446 Removal of remaining Flap from the C-strand TAS Homo sapiens 15986 R-HSA-174447 https://reactome.org/PathwayBrowser/#/R-HSA-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere TAS Homo sapiens 15986 R-HSA-174448 https://reactome.org/PathwayBrowser/#/R-HSA-174448 Formation of Processive Complex on the C-strand of the telomere TAS Homo sapiens 15986 R-HSA-174451 https://reactome.org/PathwayBrowser/#/R-HSA-174451 Recruitment of DNA2 endonuclease to the C strand TAS Homo sapiens 15986 R-HSA-174452 https://reactome.org/PathwayBrowser/#/R-HSA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere TAS Homo sapiens 15986 R-HSA-174456 https://reactome.org/PathwayBrowser/#/R-HSA-174456 Joining of adjacent Okazaki fragments of the C-strand TAS Homo sapiens 15986 R-HSA-176700 https://reactome.org/PathwayBrowser/#/R-HSA-176700 Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure TAS Homo sapiens 15986 R-HSA-176702 https://reactome.org/PathwayBrowser/#/R-HSA-176702 Disassociation of Processive Complex and Completed Telomere End TAS Homo sapiens 15986 R-HSA-181450 https://reactome.org/PathwayBrowser/#/R-HSA-181450 Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure TAS Homo sapiens 15986 R-HSA-9668597 https://reactome.org/PathwayBrowser/#/R-HSA-9668597 DNA polymerase:primase binds G-strand of the telomere TAS Homo sapiens 15986 R-HSA-9686521 https://reactome.org/PathwayBrowser/#/R-HSA-9686521 CDK2:CCNA phosphorylates TERF2 TAS Homo sapiens 15986 R-HSA-9686524 https://reactome.org/PathwayBrowser/#/R-HSA-9686524 PP6-PPP6R3 dephosphorylates TERF2 TAS Homo sapiens 15986 R-MMU-163090 https://reactome.org/PathwayBrowser/#/R-MMU-163090 Elongation Of The Telomeric Chromosome End IEA Mus musculus 15986 R-MMU-163096 https://reactome.org/PathwayBrowser/#/R-MMU-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End IEA Mus musculus 15986 R-MMU-163099 https://reactome.org/PathwayBrowser/#/R-MMU-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Mus musculus 15986 R-MMU-163120 https://reactome.org/PathwayBrowser/#/R-MMU-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Mus musculus 15986 R-MMU-164617 https://reactome.org/PathwayBrowser/#/R-MMU-164617 Elongation of Extended Telomeric Chromosome End IEA Mus musculus 15986 R-MMU-164620 https://reactome.org/PathwayBrowser/#/R-MMU-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Mus musculus 15986 R-MMU-174425 https://reactome.org/PathwayBrowser/#/R-MMU-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Mus musculus 15986 R-MMU-174427 https://reactome.org/PathwayBrowser/#/R-MMU-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Mus musculus 15986 R-MMU-174438 https://reactome.org/PathwayBrowser/#/R-MMU-174438 Formation of the Flap Intermediate on the C-strand IEA Mus musculus 15986 R-MMU-174439 https://reactome.org/PathwayBrowser/#/R-MMU-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Mus musculus 15986 R-MMU-174441 https://reactome.org/PathwayBrowser/#/R-MMU-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Mus musculus 15986 R-MMU-174444 https://reactome.org/PathwayBrowser/#/R-MMU-174444 Formation of C-strand Okazaki fragments IEA Mus musculus 15986 R-MMU-174445 https://reactome.org/PathwayBrowser/#/R-MMU-174445 RPA binds to the Flap on the C-strand IEA Mus musculus 15986 R-MMU-174446 https://reactome.org/PathwayBrowser/#/R-MMU-174446 Removal of remaining Flap from the C-strand IEA Mus musculus 15986 R-MMU-174447 https://reactome.org/PathwayBrowser/#/R-MMU-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Mus musculus 15986 R-MMU-174448 https://reactome.org/PathwayBrowser/#/R-MMU-174448 Formation of Processive Complex on the C-strand of the telomere IEA Mus musculus 15986 R-MMU-174451 https://reactome.org/PathwayBrowser/#/R-MMU-174451 Recruitment of DNA2 endonuclease to the C strand IEA Mus musculus 15986 R-MMU-174452 https://reactome.org/PathwayBrowser/#/R-MMU-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Mus musculus 15986 R-MMU-174456 https://reactome.org/PathwayBrowser/#/R-MMU-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Mus musculus 15986 R-MMU-176702 https://reactome.org/PathwayBrowser/#/R-MMU-176702 Disassociation of Processive Complex and Completed Telomere End IEA Mus musculus 15986 R-MMU-9668597 https://reactome.org/PathwayBrowser/#/R-MMU-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Mus musculus 15986 R-MMU-9686521 https://reactome.org/PathwayBrowser/#/R-MMU-9686521 CDK2:CCNA phosphorylates TERF2 IEA Mus musculus 15986 R-MMU-9686524 https://reactome.org/PathwayBrowser/#/R-MMU-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Mus musculus 15986 R-RNO-163090 https://reactome.org/PathwayBrowser/#/R-RNO-163090 Elongation Of The Telomeric Chromosome End IEA Rattus norvegicus 15986 R-RNO-163096 https://reactome.org/PathwayBrowser/#/R-RNO-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End IEA Rattus norvegicus 15986 R-RNO-163099 https://reactome.org/PathwayBrowser/#/R-RNO-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Rattus norvegicus 15986 R-RNO-163120 https://reactome.org/PathwayBrowser/#/R-RNO-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Rattus norvegicus 15986 R-RNO-164617 https://reactome.org/PathwayBrowser/#/R-RNO-164617 Elongation of Extended Telomeric Chromosome End IEA Rattus norvegicus 15986 R-RNO-164620 https://reactome.org/PathwayBrowser/#/R-RNO-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Rattus norvegicus 15986 R-RNO-174425 https://reactome.org/PathwayBrowser/#/R-RNO-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Rattus norvegicus 15986 R-RNO-174427 https://reactome.org/PathwayBrowser/#/R-RNO-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Rattus norvegicus 15986 R-RNO-174438 https://reactome.org/PathwayBrowser/#/R-RNO-174438 Formation of the Flap Intermediate on the C-strand IEA Rattus norvegicus 15986 R-RNO-174439 https://reactome.org/PathwayBrowser/#/R-RNO-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Rattus norvegicus 15986 R-RNO-174441 https://reactome.org/PathwayBrowser/#/R-RNO-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Rattus norvegicus 15986 R-RNO-174444 https://reactome.org/PathwayBrowser/#/R-RNO-174444 Formation of C-strand Okazaki fragments IEA Rattus norvegicus 15986 R-RNO-174445 https://reactome.org/PathwayBrowser/#/R-RNO-174445 RPA binds to the Flap on the C-strand IEA Rattus norvegicus 15986 R-RNO-174446 https://reactome.org/PathwayBrowser/#/R-RNO-174446 Removal of remaining Flap from the C-strand IEA Rattus norvegicus 15986 R-RNO-174447 https://reactome.org/PathwayBrowser/#/R-RNO-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Rattus norvegicus 15986 R-RNO-174448 https://reactome.org/PathwayBrowser/#/R-RNO-174448 Formation of Processive Complex on the C-strand of the telomere IEA Rattus norvegicus 15986 R-RNO-174451 https://reactome.org/PathwayBrowser/#/R-RNO-174451 Recruitment of DNA2 endonuclease to the C strand IEA Rattus norvegicus 15986 R-RNO-174452 https://reactome.org/PathwayBrowser/#/R-RNO-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Rattus norvegicus 15986 R-RNO-174456 https://reactome.org/PathwayBrowser/#/R-RNO-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Rattus norvegicus 15986 R-RNO-176702 https://reactome.org/PathwayBrowser/#/R-RNO-176702 Disassociation of Processive Complex and Completed Telomere End IEA Rattus norvegicus 15986 R-RNO-9668597 https://reactome.org/PathwayBrowser/#/R-RNO-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Rattus norvegicus 15986 R-RNO-9686521 https://reactome.org/PathwayBrowser/#/R-RNO-9686521 CDK2:CCNA phosphorylates TERF2 IEA Rattus norvegicus 15986 R-RNO-9686524 https://reactome.org/PathwayBrowser/#/R-RNO-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Rattus norvegicus 15986 R-SPO-174451 https://reactome.org/PathwayBrowser/#/R-SPO-174451 Recruitment of DNA2 endonuclease to the C strand IEA Schizosaccharomyces pombe 15986 R-SSC-163090 https://reactome.org/PathwayBrowser/#/R-SSC-163090 Elongation Of The Telomeric Chromosome End IEA Sus scrofa 15986 R-SSC-163096 https://reactome.org/PathwayBrowser/#/R-SSC-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End IEA Sus scrofa 15986 R-SSC-163099 https://reactome.org/PathwayBrowser/#/R-SSC-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Sus scrofa 15986 R-SSC-163120 https://reactome.org/PathwayBrowser/#/R-SSC-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Sus scrofa 15986 R-SSC-164617 https://reactome.org/PathwayBrowser/#/R-SSC-164617 Elongation of Extended Telomeric Chromosome End IEA Sus scrofa 15986 R-SSC-164620 https://reactome.org/PathwayBrowser/#/R-SSC-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Sus scrofa 15986 R-SSC-174425 https://reactome.org/PathwayBrowser/#/R-SSC-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Sus scrofa 15986 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa 15986 R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa 15986 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa 15986 R-SSC-174441 https://reactome.org/PathwayBrowser/#/R-SSC-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Sus scrofa 15986 R-SSC-174444 https://reactome.org/PathwayBrowser/#/R-SSC-174444 Formation of C-strand Okazaki fragments IEA Sus scrofa 15986 R-SSC-174445 https://reactome.org/PathwayBrowser/#/R-SSC-174445 RPA binds to the Flap on the C-strand IEA Sus scrofa 15986 R-SSC-174446 https://reactome.org/PathwayBrowser/#/R-SSC-174446 Removal of remaining Flap from the C-strand IEA Sus scrofa 15986 R-SSC-174447 https://reactome.org/PathwayBrowser/#/R-SSC-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Sus scrofa 15986 R-SSC-174448 https://reactome.org/PathwayBrowser/#/R-SSC-174448 Formation of Processive Complex on the C-strand of the telomere IEA Sus scrofa 15986 R-SSC-174451 https://reactome.org/PathwayBrowser/#/R-SSC-174451 Recruitment of DNA2 endonuclease to the C strand IEA Sus scrofa 15986 R-SSC-174452 https://reactome.org/PathwayBrowser/#/R-SSC-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Sus scrofa 15986 R-SSC-174456 https://reactome.org/PathwayBrowser/#/R-SSC-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Sus scrofa 15986 R-SSC-176702 https://reactome.org/PathwayBrowser/#/R-SSC-176702 Disassociation of Processive Complex and Completed Telomere End IEA Sus scrofa 15986 R-SSC-9668597 https://reactome.org/PathwayBrowser/#/R-SSC-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Sus scrofa 15986 R-SSC-9686521 https://reactome.org/PathwayBrowser/#/R-SSC-9686521 CDK2:CCNA phosphorylates TERF2 IEA Sus scrofa 15986 R-SSC-9686524 https://reactome.org/PathwayBrowser/#/R-SSC-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Sus scrofa 15986 R-XTR-174439 https://reactome.org/PathwayBrowser/#/R-XTR-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Xenopus tropicalis 15986 R-XTR-174447 https://reactome.org/PathwayBrowser/#/R-XTR-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Xenopus tropicalis 15986 R-XTR-176700 https://reactome.org/PathwayBrowser/#/R-XTR-176700 Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure IEA Xenopus tropicalis 15986 R-XTR-181450 https://reactome.org/PathwayBrowser/#/R-XTR-181450 Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure IEA Xenopus tropicalis 15986 R-XTR-9686521 https://reactome.org/PathwayBrowser/#/R-XTR-9686521 CDK2:CCNA phosphorylates TERF2 IEA Xenopus tropicalis 15986 R-XTR-9686524 https://reactome.org/PathwayBrowser/#/R-XTR-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Xenopus tropicalis 15996 R-BTA-1675883 https://reactome.org/PathwayBrowser/#/R-BTA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Bos taurus 15996 R-BTA-1676152 https://reactome.org/PathwayBrowser/#/R-BTA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Bos taurus 15996 R-BTA-2213248 https://reactome.org/PathwayBrowser/#/R-BTA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Bos taurus 15996 R-BTA-432237 https://reactome.org/PathwayBrowser/#/R-BTA-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Bos taurus 15996 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 15996 R-BTA-5624127 https://reactome.org/PathwayBrowser/#/R-BTA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Bos taurus 15996 R-BTA-5624130 https://reactome.org/PathwayBrowser/#/R-BTA-5624130 Myristoylated NPHP3 translocates into the ciliary membrane IEA Bos taurus 15996 R-BTA-5624133 https://reactome.org/PathwayBrowser/#/R-BTA-5624133 ARL3:GTP binds the UNC119B complex IEA Bos taurus 15996 R-BTA-5624949 https://reactome.org/PathwayBrowser/#/R-BTA-5624949 Assembly of the anterograde IFT train IEA Bos taurus 15996 R-BTA-5625416 https://reactome.org/PathwayBrowser/#/R-BTA-5625416 Anterograde IFT IEA Bos taurus 15996 R-BTA-5625426 https://reactome.org/PathwayBrowser/#/R-BTA-5625426 Retrograde IFT IEA Bos taurus 15996 R-BTA-5638004 https://reactome.org/PathwayBrowser/#/R-BTA-5638004 RP2 binds ARL3:GTP:UNC119B IEA Bos taurus 15996 R-BTA-5638006 https://reactome.org/PathwayBrowser/#/R-BTA-5638006 ARL3 hydrolyzes GTP IEA Bos taurus 15996 R-BTA-5638007 https://reactome.org/PathwayBrowser/#/R-BTA-5638007 RP2 activates the GTPase activity of ARL3 IEA Bos taurus 15996 R-BTA-8847880 https://reactome.org/PathwayBrowser/#/R-BTA-8847880 CYTH proteins bind ARF1:GTP IEA Bos taurus 15996 R-BTA-8847883 https://reactome.org/PathwayBrowser/#/R-BTA-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Bos taurus 15996 R-BTA-8854255 https://reactome.org/PathwayBrowser/#/R-BTA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Bos taurus 15996 R-BTA-8854329 https://reactome.org/PathwayBrowser/#/R-BTA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Bos taurus 15996 R-BTA-8854604 https://reactome.org/PathwayBrowser/#/R-BTA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Bos taurus 15996 R-BTA-8871366 https://reactome.org/PathwayBrowser/#/R-BTA-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Bos taurus 15996 R-BTA-983422 https://reactome.org/PathwayBrowser/#/R-BTA-983422 Disassembly of COPII coated vesicle IEA Bos taurus 15996 R-BTA-983424 https://reactome.org/PathwayBrowser/#/R-BTA-983424 Budding of COPII coated vesicle IEA Bos taurus 15996 R-CEL-1675883 https://reactome.org/PathwayBrowser/#/R-CEL-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Caenorhabditis elegans 15996 R-CEL-1676152 https://reactome.org/PathwayBrowser/#/R-CEL-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Caenorhabditis elegans 15996 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 15996 R-CEL-5624127 https://reactome.org/PathwayBrowser/#/R-CEL-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Caenorhabditis elegans 15996 R-CEL-5625416 https://reactome.org/PathwayBrowser/#/R-CEL-5625416 Anterograde IFT IEA Caenorhabditis elegans 15996 R-CEL-5625426 https://reactome.org/PathwayBrowser/#/R-CEL-5625426 Retrograde IFT IEA Caenorhabditis elegans 15996 R-CEL-5638004 https://reactome.org/PathwayBrowser/#/R-CEL-5638004 RP2 binds ARL3:GTP:UNC119B IEA Caenorhabditis elegans 15996 R-CEL-5638006 https://reactome.org/PathwayBrowser/#/R-CEL-5638006 ARL3 hydrolyzes GTP IEA Caenorhabditis elegans 15996 R-CEL-5638007 https://reactome.org/PathwayBrowser/#/R-CEL-5638007 RP2 activates the GTPase activity of ARL3 IEA Caenorhabditis elegans 15996 R-CEL-8854222 https://reactome.org/PathwayBrowser/#/R-CEL-8854222 TBC1D3 associates with RAB5 IEA Caenorhabditis elegans 15996 R-CEL-8854255 https://reactome.org/PathwayBrowser/#/R-CEL-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 15996 R-CEL-8854329 https://reactome.org/PathwayBrowser/#/R-CEL-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 15996 R-CFA-1675883 https://reactome.org/PathwayBrowser/#/R-CFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Canis familiaris 15996 R-CFA-1676152 https://reactome.org/PathwayBrowser/#/R-CFA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Canis familiaris 15996 R-CFA-2213248 https://reactome.org/PathwayBrowser/#/R-CFA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Canis familiaris 15996 R-CFA-432237 https://reactome.org/PathwayBrowser/#/R-CFA-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Canis familiaris 15996 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 15996 R-CFA-5624127 https://reactome.org/PathwayBrowser/#/R-CFA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Canis familiaris 15996 R-CFA-5624130 https://reactome.org/PathwayBrowser/#/R-CFA-5624130 Myristoylated NPHP3 translocates into the ciliary membrane IEA Canis familiaris 15996 R-CFA-5624133 https://reactome.org/PathwayBrowser/#/R-CFA-5624133 ARL3:GTP binds the UNC119B complex IEA Canis familiaris 15996 R-CFA-5624949 https://reactome.org/PathwayBrowser/#/R-CFA-5624949 Assembly of the anterograde IFT train IEA Canis familiaris 15996 R-CFA-5624952 https://reactome.org/PathwayBrowser/#/R-CFA-5624952 Assembly of the retrograde IFT train IEA Canis familiaris 15996 R-CFA-5625416 https://reactome.org/PathwayBrowser/#/R-CFA-5625416 Anterograde IFT IEA Canis familiaris 15996 R-CFA-5625421 https://reactome.org/PathwayBrowser/#/R-CFA-5625421 The anterograde IFT train dissociates IEA Canis familiaris 15996 R-CFA-5625424 https://reactome.org/PathwayBrowser/#/R-CFA-5625424 The retrograde IFT train dissociates IEA Canis familiaris 15996 R-CFA-5625426 https://reactome.org/PathwayBrowser/#/R-CFA-5625426 Retrograde IFT IEA Canis familiaris 15996 R-CFA-5638004 https://reactome.org/PathwayBrowser/#/R-CFA-5638004 RP2 binds ARL3:GTP:UNC119B IEA Canis familiaris 15996 R-CFA-5638006 https://reactome.org/PathwayBrowser/#/R-CFA-5638006 ARL3 hydrolyzes GTP IEA Canis familiaris 15996 R-CFA-5638007 https://reactome.org/PathwayBrowser/#/R-CFA-5638007 RP2 activates the GTPase activity of ARL3 IEA Canis familiaris 15996 R-CFA-8847875 https://reactome.org/PathwayBrowser/#/R-CFA-8847875 ARF1:GTP binds Golgin TRIP11 IEA Canis familiaris 15996 R-CFA-8847880 https://reactome.org/PathwayBrowser/#/R-CFA-8847880 CYTH proteins bind ARF1:GTP IEA Canis familiaris 15996 R-CFA-8847883 https://reactome.org/PathwayBrowser/#/R-CFA-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Canis familiaris 15996 R-CFA-8854255 https://reactome.org/PathwayBrowser/#/R-CFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 15996 R-CFA-8854329 https://reactome.org/PathwayBrowser/#/R-CFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 15996 R-CFA-8854604 https://reactome.org/PathwayBrowser/#/R-CFA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Canis familiaris 15996 R-CFA-983422 https://reactome.org/PathwayBrowser/#/R-CFA-983422 Disassembly of COPII coated vesicle IEA Canis familiaris 15996 R-CFA-983424 https://reactome.org/PathwayBrowser/#/R-CFA-983424 Budding of COPII coated vesicle IEA Canis familiaris 15996 R-DDI-1675883 https://reactome.org/PathwayBrowser/#/R-DDI-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Dictyostelium discoideum 15996 R-DDI-1676152 https://reactome.org/PathwayBrowser/#/R-DDI-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Dictyostelium discoideum 15996 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 15996 R-DDI-8847880 https://reactome.org/PathwayBrowser/#/R-DDI-8847880 CYTH proteins bind ARF1:GTP IEA Dictyostelium discoideum 15996 R-DDI-8847883 https://reactome.org/PathwayBrowser/#/R-DDI-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Dictyostelium discoideum 15996 R-DDI-8854255 https://reactome.org/PathwayBrowser/#/R-DDI-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 15996 R-DDI-8854329 https://reactome.org/PathwayBrowser/#/R-DDI-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 15996 R-DDI-8854604 https://reactome.org/PathwayBrowser/#/R-DDI-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Dictyostelium discoideum 15996 R-DME-1675883 https://reactome.org/PathwayBrowser/#/R-DME-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Drosophila melanogaster 15996 R-DME-1676152 https://reactome.org/PathwayBrowser/#/R-DME-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Drosophila melanogaster 15996 R-DME-432237 https://reactome.org/PathwayBrowser/#/R-DME-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Drosophila melanogaster 15996 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 15996 R-DME-8847875 https://reactome.org/PathwayBrowser/#/R-DME-8847875 ARF1:GTP binds Golgin TRIP11 IEA Drosophila melanogaster 15996 R-DME-8847880 https://reactome.org/PathwayBrowser/#/R-DME-8847880 CYTH proteins bind ARF1:GTP IEA Drosophila melanogaster 15996 R-DME-8847883 https://reactome.org/PathwayBrowser/#/R-DME-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Drosophila melanogaster 15996 R-DME-8854222 https://reactome.org/PathwayBrowser/#/R-DME-8854222 TBC1D3 associates with RAB5 IEA Drosophila melanogaster 15996 R-DME-8854255 https://reactome.org/PathwayBrowser/#/R-DME-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 15996 R-DME-8854329 https://reactome.org/PathwayBrowser/#/R-DME-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 15996 R-DME-8854604 https://reactome.org/PathwayBrowser/#/R-DME-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Drosophila melanogaster 15996 R-DME-8871366 https://reactome.org/PathwayBrowser/#/R-DME-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Drosophila melanogaster 15996 R-DRE-1675883 https://reactome.org/PathwayBrowser/#/R-DRE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Danio rerio 15996 R-DRE-1676152 https://reactome.org/PathwayBrowser/#/R-DRE-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Danio rerio 15996 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 15996 R-DRE-5624130 https://reactome.org/PathwayBrowser/#/R-DRE-5624130 Myristoylated NPHP3 translocates into the ciliary membrane IEA Danio rerio 15996 R-DRE-5624133 https://reactome.org/PathwayBrowser/#/R-DRE-5624133 ARL3:GTP binds the UNC119B complex IEA Danio rerio 15996 R-DRE-5638004 https://reactome.org/PathwayBrowser/#/R-DRE-5638004 RP2 binds ARL3:GTP:UNC119B IEA Danio rerio 15996 R-DRE-5638006 https://reactome.org/PathwayBrowser/#/R-DRE-5638006 ARL3 hydrolyzes GTP IEA Danio rerio 15996 R-DRE-5638007 https://reactome.org/PathwayBrowser/#/R-DRE-5638007 RP2 activates the GTPase activity of ARL3 IEA Danio rerio 15996 R-DRE-8854255 https://reactome.org/PathwayBrowser/#/R-DRE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Danio rerio 15996 R-DRE-8854329 https://reactome.org/PathwayBrowser/#/R-DRE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Danio rerio 15996 R-DRE-8854604 https://reactome.org/PathwayBrowser/#/R-DRE-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Danio rerio 15996 R-DRE-983424 https://reactome.org/PathwayBrowser/#/R-DRE-983424 Budding of COPII coated vesicle IEA Danio rerio 15996 R-GGA-1675883 https://reactome.org/PathwayBrowser/#/R-GGA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Gallus gallus 15996 R-GGA-1676152 https://reactome.org/PathwayBrowser/#/R-GGA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Gallus gallus 15996 R-GGA-432237 https://reactome.org/PathwayBrowser/#/R-GGA-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Gallus gallus 15996 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 15996 R-GGA-5624127 https://reactome.org/PathwayBrowser/#/R-GGA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Gallus gallus 15996 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus 15996 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus 15996 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus 15996 R-GGA-5638004 https://reactome.org/PathwayBrowser/#/R-GGA-5638004 RP2 binds ARL3:GTP:UNC119B IEA Gallus gallus 15996 R-GGA-5638006 https://reactome.org/PathwayBrowser/#/R-GGA-5638006 ARL3 hydrolyzes GTP IEA Gallus gallus 15996 R-GGA-5638007 https://reactome.org/PathwayBrowser/#/R-GGA-5638007 RP2 activates the GTPase activity of ARL3 IEA Gallus gallus 15996 R-GGA-8847875 https://reactome.org/PathwayBrowser/#/R-GGA-8847875 ARF1:GTP binds Golgin TRIP11 IEA Gallus gallus 15996 R-GGA-8847880 https://reactome.org/PathwayBrowser/#/R-GGA-8847880 CYTH proteins bind ARF1:GTP IEA Gallus gallus 15996 R-GGA-8847883 https://reactome.org/PathwayBrowser/#/R-GGA-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Gallus gallus 15996 R-GGA-8854222 https://reactome.org/PathwayBrowser/#/R-GGA-8854222 TBC1D3 associates with RAB5 IEA Gallus gallus 15996 R-GGA-8854255 https://reactome.org/PathwayBrowser/#/R-GGA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 15996 R-GGA-8854329 https://reactome.org/PathwayBrowser/#/R-GGA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 15996 R-GGA-8854604 https://reactome.org/PathwayBrowser/#/R-GGA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Gallus gallus 15996 R-GGA-8871366 https://reactome.org/PathwayBrowser/#/R-GGA-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Gallus gallus 15996 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus 15996 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus 15996 R-HSA-1445143 https://reactome.org/PathwayBrowser/#/R-HSA-1445143 RAB8A,10,13,14 hydrolyze GTP IEA Homo sapiens 15996 R-HSA-1458485 https://reactome.org/PathwayBrowser/#/R-HSA-1458485 RALA hydrolyzes GTP IEA Homo sapiens 15996 R-HSA-1675883 https://reactome.org/PathwayBrowser/#/R-HSA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane TAS Homo sapiens 15996 R-HSA-1676152 https://reactome.org/PathwayBrowser/#/R-HSA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane TAS Homo sapiens 15996 R-HSA-2213248 https://reactome.org/PathwayBrowser/#/R-HSA-2213248 Transport of antigen loaded MHC II molecules to surface TAS Homo sapiens 15996 R-HSA-2255342 https://reactome.org/PathwayBrowser/#/R-HSA-2255342 RALA exchanges GDP for GTP IEA Homo sapiens 15996 R-HSA-2255343 https://reactome.org/PathwayBrowser/#/R-HSA-2255343 RAB8A,10,13,14 exchange GDP for GTP IEA Homo sapiens 15996 R-HSA-2316347 https://reactome.org/PathwayBrowser/#/R-HSA-2316347 RAB4A:GTP binds KIF3 and activates KIF3 IEA Homo sapiens 15996 R-HSA-2316349 https://reactome.org/PathwayBrowser/#/R-HSA-2316349 RALA:GTP binds MYO1C:CALM1 and activates MYO1C IEA Homo sapiens 15996 R-HSA-2316352 https://reactome.org/PathwayBrowser/#/R-HSA-2316352 SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane IEA Homo sapiens 15996 R-HSA-432237 https://reactome.org/PathwayBrowser/#/R-HSA-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane TAS Homo sapiens 15996 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 15996 R-HSA-5624127 https://reactome.org/PathwayBrowser/#/R-HSA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium TAS Homo sapiens 15996 R-HSA-5624130 https://reactome.org/PathwayBrowser/#/R-HSA-5624130 Myristoylated NPHP3 translocates into the ciliary membrane TAS Homo sapiens 15996 R-HSA-5624133 https://reactome.org/PathwayBrowser/#/R-HSA-5624133 ARL3:GTP binds the UNC119B complex TAS Homo sapiens 15996 R-HSA-5624949 https://reactome.org/PathwayBrowser/#/R-HSA-5624949 Assembly of the anterograde IFT train TAS Homo sapiens 15996 R-HSA-5624952 https://reactome.org/PathwayBrowser/#/R-HSA-5624952 Assembly of the retrograde IFT train TAS Homo sapiens 15996 R-HSA-5625416 https://reactome.org/PathwayBrowser/#/R-HSA-5625416 Anterograde IFT TAS Homo sapiens 15996 R-HSA-5625421 https://reactome.org/PathwayBrowser/#/R-HSA-5625421 The anterograde IFT train dissociates TAS Homo sapiens 15996 R-HSA-5625424 https://reactome.org/PathwayBrowser/#/R-HSA-5625424 The retrograde IFT train dissociates TAS Homo sapiens 15996 R-HSA-5625426 https://reactome.org/PathwayBrowser/#/R-HSA-5625426 Retrograde IFT TAS Homo sapiens 15996 R-HSA-5638004 https://reactome.org/PathwayBrowser/#/R-HSA-5638004 RP2 binds ARL3:GTP:UNC119B TAS Homo sapiens 15996 R-HSA-5638006 https://reactome.org/PathwayBrowser/#/R-HSA-5638006 ARL3 hydrolyzes GTP TAS Homo sapiens 15996 R-HSA-5638007 https://reactome.org/PathwayBrowser/#/R-HSA-5638007 RP2 activates the GTPase activity of ARL3 TAS Homo sapiens 15996 R-HSA-8847875 https://reactome.org/PathwayBrowser/#/R-HSA-8847875 ARF1:GTP binds Golgin TRIP11 TAS Homo sapiens 15996 R-HSA-8847880 https://reactome.org/PathwayBrowser/#/R-HSA-8847880 CYTH proteins bind ARF1:GTP TAS Homo sapiens 15996 R-HSA-8847883 https://reactome.org/PathwayBrowser/#/R-HSA-8847883 CYTH proteins stimulate ARF1 GTPase activity TAS Homo sapiens 15996 R-HSA-8854222 https://reactome.org/PathwayBrowser/#/R-HSA-8854222 TBC1D3 associates with RAB5 TAS Homo sapiens 15996 R-HSA-8854255 https://reactome.org/PathwayBrowser/#/R-HSA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 15996 R-HSA-8854329 https://reactome.org/PathwayBrowser/#/R-HSA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 15996 R-HSA-8854604 https://reactome.org/PathwayBrowser/#/R-HSA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A TAS Homo sapiens 15996 R-HSA-8871366 https://reactome.org/PathwayBrowser/#/R-HSA-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP TAS Homo sapiens 15996 R-HSA-983422 https://reactome.org/PathwayBrowser/#/R-HSA-983422 Disassembly of COPII coated vesicle TAS Homo sapiens 15996 R-HSA-983424 https://reactome.org/PathwayBrowser/#/R-HSA-983424 Budding of COPII coated vesicle TAS Homo sapiens 15996 R-MMU-1449633 https://reactome.org/PathwayBrowser/#/R-MMU-1449633 Rab8a/10/13/14 Hydrolyze GTP TAS Mus musculus 15996 R-MMU-1458501 https://reactome.org/PathwayBrowser/#/R-MMU-1458501 RalA Hydrolyzes GTP TAS Mus musculus 15996 R-MMU-1675883 https://reactome.org/PathwayBrowser/#/R-MMU-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Mus musculus 15996 R-MMU-1676152 https://reactome.org/PathwayBrowser/#/R-MMU-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Mus musculus 15996 R-MMU-2213248 https://reactome.org/PathwayBrowser/#/R-MMU-2213248 Transport of antigen loaded MHC II molecules to surface IEA Mus musculus 15996 R-MMU-2255339 https://reactome.org/PathwayBrowser/#/R-MMU-2255339 RalA Exchanges GDP for GTP TAS Mus musculus 15996 R-MMU-2255341 https://reactome.org/PathwayBrowser/#/R-MMU-2255341 Rab8A/10/13/14 Exchange GDP for GTP TAS Mus musculus 15996 R-MMU-2316348 https://reactome.org/PathwayBrowser/#/R-MMU-2316348 RalA:GTP binds Myo1c:Calm1 and F-actin TAS Mus musculus 15996 R-MMU-2316350 https://reactome.org/PathwayBrowser/#/R-MMU-2316350 Rab4a:GTP Activates Kif3 TAS Mus musculus 15996 R-MMU-2316351 https://reactome.org/PathwayBrowser/#/R-MMU-2316351 Translocation of Glut4 Vesicle and Docking at the Plasma Membrane TAS Mus musculus 15996 R-MMU-432237 https://reactome.org/PathwayBrowser/#/R-MMU-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Mus musculus 15996 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 15996 R-MMU-5624127 https://reactome.org/PathwayBrowser/#/R-MMU-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Mus musculus 15996 R-MMU-5624130 https://reactome.org/PathwayBrowser/#/R-MMU-5624130 Myristoylated NPHP3 translocates into the ciliary membrane IEA Mus musculus 15996 R-MMU-5624133 https://reactome.org/PathwayBrowser/#/R-MMU-5624133 ARL3:GTP binds the UNC119B complex IEA Mus musculus 15996 R-MMU-5624949 https://reactome.org/PathwayBrowser/#/R-MMU-5624949 Assembly of the anterograde IFT train IEA Mus musculus 15996 R-MMU-5624952 https://reactome.org/PathwayBrowser/#/R-MMU-5624952 Assembly of the retrograde IFT train IEA Mus musculus 15996 R-MMU-5625416 https://reactome.org/PathwayBrowser/#/R-MMU-5625416 Anterograde IFT IEA Mus musculus 15996 R-MMU-5625421 https://reactome.org/PathwayBrowser/#/R-MMU-5625421 The anterograde IFT train dissociates IEA Mus musculus 15996 R-MMU-5625424 https://reactome.org/PathwayBrowser/#/R-MMU-5625424 The retrograde IFT train dissociates IEA Mus musculus 15996 R-MMU-5625426 https://reactome.org/PathwayBrowser/#/R-MMU-5625426 Retrograde IFT IEA Mus musculus 15996 R-MMU-5638004 https://reactome.org/PathwayBrowser/#/R-MMU-5638004 RP2 binds ARL3:GTP:UNC119B IEA Mus musculus 15996 R-MMU-5638006 https://reactome.org/PathwayBrowser/#/R-MMU-5638006 ARL3 hydrolyzes GTP IEA Mus musculus 15996 R-MMU-5638007 https://reactome.org/PathwayBrowser/#/R-MMU-5638007 RP2 activates the GTPase activity of ARL3 IEA Mus musculus 15996 R-MMU-8847875 https://reactome.org/PathwayBrowser/#/R-MMU-8847875 ARF1:GTP binds Golgin TRIP11 IEA Mus musculus 15996 R-MMU-8847880 https://reactome.org/PathwayBrowser/#/R-MMU-8847880 CYTH proteins bind ARF1:GTP IEA Mus musculus 15996 R-MMU-8847883 https://reactome.org/PathwayBrowser/#/R-MMU-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Mus musculus 15996 R-MMU-8854255 https://reactome.org/PathwayBrowser/#/R-MMU-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Mus musculus 15996 R-MMU-8854329 https://reactome.org/PathwayBrowser/#/R-MMU-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Mus musculus 15996 R-MMU-8854604 https://reactome.org/PathwayBrowser/#/R-MMU-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Mus musculus 15996 R-MMU-8871366 https://reactome.org/PathwayBrowser/#/R-MMU-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Mus musculus 15996 R-MMU-983422 https://reactome.org/PathwayBrowser/#/R-MMU-983422 Disassembly of COPII coated vesicle IEA Mus musculus 15996 R-MMU-983424 https://reactome.org/PathwayBrowser/#/R-MMU-983424 Budding of COPII coated vesicle IEA Mus musculus 15996 R-PFA-1675883 https://reactome.org/PathwayBrowser/#/R-PFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Plasmodium falciparum 15996 R-PFA-1676152 https://reactome.org/PathwayBrowser/#/R-PFA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Plasmodium falciparum 15996 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 15996 R-PFA-8854255 https://reactome.org/PathwayBrowser/#/R-PFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 15996 R-PFA-8854329 https://reactome.org/PathwayBrowser/#/R-PFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 15996 R-RNO-1675883 https://reactome.org/PathwayBrowser/#/R-RNO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Rattus norvegicus 15996 R-RNO-1676152 https://reactome.org/PathwayBrowser/#/R-RNO-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Rattus norvegicus 15996 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus 15996 R-RNO-2457808 https://reactome.org/PathwayBrowser/#/R-RNO-2457808 Rab8A/13/14 Exchange GDP for GTP TAS Rattus norvegicus 15996 R-RNO-432237 https://reactome.org/PathwayBrowser/#/R-RNO-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Rattus norvegicus 15996 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 15996 R-RNO-5624127 https://reactome.org/PathwayBrowser/#/R-RNO-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Rattus norvegicus 15996 R-RNO-5624130 https://reactome.org/PathwayBrowser/#/R-RNO-5624130 Myristoylated NPHP3 translocates into the ciliary membrane IEA Rattus norvegicus 15996 R-RNO-5624133 https://reactome.org/PathwayBrowser/#/R-RNO-5624133 ARL3:GTP binds the UNC119B complex IEA Rattus norvegicus 15996 R-RNO-5624949 https://reactome.org/PathwayBrowser/#/R-RNO-5624949 Assembly of the anterograde IFT train IEA Rattus norvegicus 15996 R-RNO-5624952 https://reactome.org/PathwayBrowser/#/R-RNO-5624952 Assembly of the retrograde IFT train IEA Rattus norvegicus 15996 R-RNO-5625416 https://reactome.org/PathwayBrowser/#/R-RNO-5625416 Anterograde IFT IEA Rattus norvegicus 15996 R-RNO-5625421 https://reactome.org/PathwayBrowser/#/R-RNO-5625421 The anterograde IFT train dissociates IEA Rattus norvegicus 15996 R-RNO-5625424 https://reactome.org/PathwayBrowser/#/R-RNO-5625424 The retrograde IFT train dissociates IEA Rattus norvegicus 15996 R-RNO-5625426 https://reactome.org/PathwayBrowser/#/R-RNO-5625426 Retrograde IFT IEA Rattus norvegicus 15996 R-RNO-5638004 https://reactome.org/PathwayBrowser/#/R-RNO-5638004 RP2 binds ARL3:GTP:UNC119B IEA Rattus norvegicus 15996 R-RNO-5638006 https://reactome.org/PathwayBrowser/#/R-RNO-5638006 ARL3 hydrolyzes GTP IEA Rattus norvegicus 15996 R-RNO-5638007 https://reactome.org/PathwayBrowser/#/R-RNO-5638007 RP2 activates the GTPase activity of ARL3 IEA Rattus norvegicus 15996 R-RNO-8847875 https://reactome.org/PathwayBrowser/#/R-RNO-8847875 ARF1:GTP binds Golgin TRIP11 IEA Rattus norvegicus 15996 R-RNO-8847880 https://reactome.org/PathwayBrowser/#/R-RNO-8847880 CYTH proteins bind ARF1:GTP IEA Rattus norvegicus 15996 R-RNO-8847883 https://reactome.org/PathwayBrowser/#/R-RNO-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Rattus norvegicus 15996 R-RNO-8854255 https://reactome.org/PathwayBrowser/#/R-RNO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 15996 R-RNO-8854329 https://reactome.org/PathwayBrowser/#/R-RNO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 15996 R-RNO-8854604 https://reactome.org/PathwayBrowser/#/R-RNO-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Rattus norvegicus 15996 R-RNO-8871366 https://reactome.org/PathwayBrowser/#/R-RNO-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Rattus norvegicus 15996 R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus 15996 R-RNO-983424 https://reactome.org/PathwayBrowser/#/R-RNO-983424 Budding of COPII coated vesicle IEA Rattus norvegicus 15996 R-SCE-1675883 https://reactome.org/PathwayBrowser/#/R-SCE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Saccharomyces cerevisiae 15996 R-SCE-1676152 https://reactome.org/PathwayBrowser/#/R-SCE-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Saccharomyces cerevisiae 15996 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 15996 R-SCE-8847880 https://reactome.org/PathwayBrowser/#/R-SCE-8847880 CYTH proteins bind ARF1:GTP IEA Saccharomyces cerevisiae 15996 R-SCE-8847883 https://reactome.org/PathwayBrowser/#/R-SCE-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Saccharomyces cerevisiae 15996 R-SCE-8854255 https://reactome.org/PathwayBrowser/#/R-SCE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 15996 R-SCE-8854329 https://reactome.org/PathwayBrowser/#/R-SCE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 15996 R-SPO-1675883 https://reactome.org/PathwayBrowser/#/R-SPO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Schizosaccharomyces pombe 15996 R-SPO-1676152 https://reactome.org/PathwayBrowser/#/R-SPO-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Schizosaccharomyces pombe 15996 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 15996 R-SPO-8847880 https://reactome.org/PathwayBrowser/#/R-SPO-8847880 CYTH proteins bind ARF1:GTP IEA Schizosaccharomyces pombe 15996 R-SPO-8847883 https://reactome.org/PathwayBrowser/#/R-SPO-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Schizosaccharomyces pombe 15996 R-SPO-8854255 https://reactome.org/PathwayBrowser/#/R-SPO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 15996 R-SPO-8854329 https://reactome.org/PathwayBrowser/#/R-SPO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 15996 R-SSC-1675883 https://reactome.org/PathwayBrowser/#/R-SSC-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Sus scrofa 15996 R-SSC-1676152 https://reactome.org/PathwayBrowser/#/R-SSC-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Sus scrofa 15996 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa 15996 R-SSC-432237 https://reactome.org/PathwayBrowser/#/R-SSC-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Sus scrofa 15996 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 15996 R-SSC-5624127 https://reactome.org/PathwayBrowser/#/R-SSC-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Sus scrofa 15996 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa 15996 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa 15996 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa 15996 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa 15996 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa 15996 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa 15996 R-SSC-8847875 https://reactome.org/PathwayBrowser/#/R-SSC-8847875 ARF1:GTP binds Golgin TRIP11 IEA Sus scrofa 15996 R-SSC-8847880 https://reactome.org/PathwayBrowser/#/R-SSC-8847880 CYTH proteins bind ARF1:GTP IEA Sus scrofa 15996 R-SSC-8847883 https://reactome.org/PathwayBrowser/#/R-SSC-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Sus scrofa 15996 R-SSC-8854222 https://reactome.org/PathwayBrowser/#/R-SSC-8854222 TBC1D3 associates with RAB5 IEA Sus scrofa 15996 R-SSC-8854255 https://reactome.org/PathwayBrowser/#/R-SSC-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 15996 R-SSC-8854329 https://reactome.org/PathwayBrowser/#/R-SSC-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 15996 R-SSC-8854604 https://reactome.org/PathwayBrowser/#/R-SSC-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Sus scrofa 15996 R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa 15996 R-SSC-983424 https://reactome.org/PathwayBrowser/#/R-SSC-983424 Budding of COPII coated vesicle IEA Sus scrofa 15996 R-XTR-1675883 https://reactome.org/PathwayBrowser/#/R-XTR-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Xenopus tropicalis 15996 R-XTR-1676152 https://reactome.org/PathwayBrowser/#/R-XTR-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Xenopus tropicalis 15996 R-XTR-432237 https://reactome.org/PathwayBrowser/#/R-XTR-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Xenopus tropicalis 15996 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 15996 R-XTR-8847875 https://reactome.org/PathwayBrowser/#/R-XTR-8847875 ARF1:GTP binds Golgin TRIP11 IEA Xenopus tropicalis 15996 R-XTR-8847880 https://reactome.org/PathwayBrowser/#/R-XTR-8847880 CYTH proteins bind ARF1:GTP IEA Xenopus tropicalis 15996 R-XTR-8847883 https://reactome.org/PathwayBrowser/#/R-XTR-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Xenopus tropicalis 15996 R-XTR-8854255 https://reactome.org/PathwayBrowser/#/R-XTR-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 15996 R-XTR-8854329 https://reactome.org/PathwayBrowser/#/R-XTR-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 15996 R-XTR-983424 https://reactome.org/PathwayBrowser/#/R-XTR-983424 Budding of COPII coated vesicle IEA Xenopus tropicalis 16000 R-BTA-1483089 https://reactome.org/PathwayBrowser/#/R-BTA-1483089 PE is converted to PS by PTDSS2 IEA Bos taurus 16000 R-BTA-1483096 https://reactome.org/PathwayBrowser/#/R-BTA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Bos taurus 16000 R-BTA-1483222 https://reactome.org/PathwayBrowser/#/R-BTA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Bos taurus 16000 R-BTA-5693742 https://reactome.org/PathwayBrowser/#/R-BTA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Bos taurus 16000 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 16000 R-CEL-1483222 https://reactome.org/PathwayBrowser/#/R-CEL-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Caenorhabditis elegans 16000 R-CEL-5693742 https://reactome.org/PathwayBrowser/#/R-CEL-5693742 FAAH hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 16000 R-CEL-5693751 https://reactome.org/PathwayBrowser/#/R-CEL-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 16000 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 16000 R-CFA-1483089 https://reactome.org/PathwayBrowser/#/R-CFA-1483089 PE is converted to PS by PTDSS2 IEA Canis familiaris 16000 R-CFA-1483096 https://reactome.org/PathwayBrowser/#/R-CFA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Canis familiaris 16000 R-CFA-1483222 https://reactome.org/PathwayBrowser/#/R-CFA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Canis familiaris 16000 R-CFA-5693742 https://reactome.org/PathwayBrowser/#/R-CFA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Canis familiaris 16000 R-DDI-1483089 https://reactome.org/PathwayBrowser/#/R-DDI-1483089 PE is converted to PS by PTDSS2 IEA Dictyostelium discoideum 16000 R-DDI-1483222 https://reactome.org/PathwayBrowser/#/R-DDI-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Dictyostelium discoideum 16000 R-DME-1483096 https://reactome.org/PathwayBrowser/#/R-DME-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Drosophila melanogaster 16000 R-DME-1483222 https://reactome.org/PathwayBrowser/#/R-DME-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Drosophila melanogaster 16000 R-DME-5693751 https://reactome.org/PathwayBrowser/#/R-DME-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Drosophila melanogaster 16000 R-DRE-1483089 https://reactome.org/PathwayBrowser/#/R-DRE-1483089 PE is converted to PS by PTDSS2 IEA Danio rerio 16000 R-DRE-1483096 https://reactome.org/PathwayBrowser/#/R-DRE-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Danio rerio 16000 R-DRE-1483222 https://reactome.org/PathwayBrowser/#/R-DRE-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Danio rerio 16000 R-DRE-5693751 https://reactome.org/PathwayBrowser/#/R-DRE-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Danio rerio 16000 R-GGA-1483089 https://reactome.org/PathwayBrowser/#/R-GGA-1483089 PE is converted to PS by PTDSS2 IEA Gallus gallus 16000 R-GGA-1483096 https://reactome.org/PathwayBrowser/#/R-GGA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Gallus gallus 16000 R-GGA-1483222 https://reactome.org/PathwayBrowser/#/R-GGA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Gallus gallus 16000 R-GGA-5693742 https://reactome.org/PathwayBrowser/#/R-GGA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Gallus gallus 16000 R-GGA-5693751 https://reactome.org/PathwayBrowser/#/R-GGA-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Gallus gallus 16000 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 16000 R-HSA-1483089 https://reactome.org/PathwayBrowser/#/R-HSA-1483089 PE is converted to PS by PTDSS2 TAS Homo sapiens 16000 R-HSA-1483096 https://reactome.org/PathwayBrowser/#/R-HSA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 TAS Homo sapiens 16000 R-HSA-1483107 https://reactome.org/PathwayBrowser/#/R-HSA-1483107 GPETA is hydrolyzed to ETA and G3P by GPCPD1 IEA Homo sapiens 16000 R-HSA-1483222 https://reactome.org/PathwayBrowser/#/R-HSA-1483222 ETA is phosphorylated to PETA by CHK/ETNK TAS Homo sapiens 16000 R-HSA-5693742 https://reactome.org/PathwayBrowser/#/R-HSA-5693742 FAAH hydrolyses AEA to AA and ETA TAS Homo sapiens 16000 R-HSA-5693751 https://reactome.org/PathwayBrowser/#/R-HSA-5693751 FAAH2 hydrolyses AEA to AA and ETA TAS Homo sapiens 16000 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 16000 R-MMU-1483089 https://reactome.org/PathwayBrowser/#/R-MMU-1483089 PE is converted to PS by PTDSS2 IEA Mus musculus 16000 R-MMU-1483096 https://reactome.org/PathwayBrowser/#/R-MMU-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Mus musculus 16000 R-MMU-1483222 https://reactome.org/PathwayBrowser/#/R-MMU-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Mus musculus 16000 R-MMU-1483231 https://reactome.org/PathwayBrowser/#/R-MMU-1483231 GPETA is hydrolyzed to ETA and G3P by Gpcpd1 TAS Mus musculus 16000 R-MMU-5693742 https://reactome.org/PathwayBrowser/#/R-MMU-5693742 FAAH hydrolyses AEA to AA and ETA IEA Mus musculus 16000 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 16000 R-PFA-1483089 https://reactome.org/PathwayBrowser/#/R-PFA-1483089 PE is converted to PS by PTDSS2 IEA Plasmodium falciparum 16000 R-PFA-1483222 https://reactome.org/PathwayBrowser/#/R-PFA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Plasmodium falciparum 16000 R-RNO-1483089 https://reactome.org/PathwayBrowser/#/R-RNO-1483089 PE is converted to PS by PTDSS2 IEA Rattus norvegicus 16000 R-RNO-1483096 https://reactome.org/PathwayBrowser/#/R-RNO-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Rattus norvegicus 16000 R-RNO-1483222 https://reactome.org/PathwayBrowser/#/R-RNO-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Rattus norvegicus 16000 R-RNO-5693742 https://reactome.org/PathwayBrowser/#/R-RNO-5693742 FAAH hydrolyses AEA to AA and ETA IEA Rattus norvegicus 16000 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 16000 R-SCE-1483222 https://reactome.org/PathwayBrowser/#/R-SCE-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Saccharomyces cerevisiae 16000 R-SPO-1483222 https://reactome.org/PathwayBrowser/#/R-SPO-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Schizosaccharomyces pombe 16000 R-SSC-1483089 https://reactome.org/PathwayBrowser/#/R-SSC-1483089 PE is converted to PS by PTDSS2 IEA Sus scrofa 16000 R-SSC-1483096 https://reactome.org/PathwayBrowser/#/R-SSC-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Sus scrofa 16000 R-SSC-1483222 https://reactome.org/PathwayBrowser/#/R-SSC-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Sus scrofa 16000 R-SSC-5693742 https://reactome.org/PathwayBrowser/#/R-SSC-5693742 FAAH hydrolyses AEA to AA and ETA IEA Sus scrofa 16000 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 16000 R-XTR-1483089 https://reactome.org/PathwayBrowser/#/R-XTR-1483089 PE is converted to PS by PTDSS2 IEA Xenopus tropicalis 16000 R-XTR-1483096 https://reactome.org/PathwayBrowser/#/R-XTR-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Xenopus tropicalis 16000 R-XTR-1483222 https://reactome.org/PathwayBrowser/#/R-XTR-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Xenopus tropicalis 16000 R-XTR-5693742 https://reactome.org/PathwayBrowser/#/R-XTR-5693742 FAAH hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 16000 R-XTR-5693751 https://reactome.org/PathwayBrowser/#/R-XTR-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 16000 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 16004 R-BTA-6783221 https://reactome.org/PathwayBrowser/#/R-BTA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Bos taurus 16004 R-CEL-6783221 https://reactome.org/PathwayBrowser/#/R-CEL-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Caenorhabditis elegans 16004 R-CFA-6783221 https://reactome.org/PathwayBrowser/#/R-CFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Canis familiaris 16004 R-DDI-6783221 https://reactome.org/PathwayBrowser/#/R-DDI-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Dictyostelium discoideum 16004 R-DME-6783221 https://reactome.org/PathwayBrowser/#/R-DME-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Drosophila melanogaster 16004 R-DRE-6783221 https://reactome.org/PathwayBrowser/#/R-DRE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Danio rerio 16004 R-GGA-6783221 https://reactome.org/PathwayBrowser/#/R-GGA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Gallus gallus 16004 R-HSA-6783221 https://reactome.org/PathwayBrowser/#/R-HSA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT TAS Homo sapiens 16004 R-MMU-6783221 https://reactome.org/PathwayBrowser/#/R-MMU-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Mus musculus 16004 R-PFA-6783221 https://reactome.org/PathwayBrowser/#/R-PFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Plasmodium falciparum 16004 R-RNO-6783221 https://reactome.org/PathwayBrowser/#/R-RNO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Rattus norvegicus 16004 R-SCE-6783221 https://reactome.org/PathwayBrowser/#/R-SCE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Saccharomyces cerevisiae 16004 R-SPO-6783221 https://reactome.org/PathwayBrowser/#/R-SPO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Schizosaccharomyces pombe 16004 R-SSC-6783221 https://reactome.org/PathwayBrowser/#/R-SSC-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Sus scrofa 16004 R-XTR-6783221 https://reactome.org/PathwayBrowser/#/R-XTR-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Xenopus tropicalis 1604 R-BTA-191763 https://reactome.org/PathwayBrowser/#/R-BTA-191763 snRNP:Snurportin complex formation IEA Bos taurus 1604 R-BTA-191784 https://reactome.org/PathwayBrowser/#/R-BTA-191784 snRNA Cap hypermethylation IEA Bos taurus 1604 R-BTA-191830 https://reactome.org/PathwayBrowser/#/R-BTA-191830 snRNP nuclear import and release IEA Bos taurus 1604 R-CEL-191763 https://reactome.org/PathwayBrowser/#/R-CEL-191763 snRNP:Snurportin complex formation IEA Caenorhabditis elegans 1604 R-CEL-191784 https://reactome.org/PathwayBrowser/#/R-CEL-191784 snRNA Cap hypermethylation IEA Caenorhabditis elegans 1604 R-CFA-191763 https://reactome.org/PathwayBrowser/#/R-CFA-191763 snRNP:Snurportin complex formation IEA Canis familiaris 1604 R-CFA-191784 https://reactome.org/PathwayBrowser/#/R-CFA-191784 snRNA Cap hypermethylation IEA Canis familiaris 1604 R-CFA-191830 https://reactome.org/PathwayBrowser/#/R-CFA-191830 snRNP nuclear import and release IEA Canis familiaris 1604 R-GGA-191763 https://reactome.org/PathwayBrowser/#/R-GGA-191763 snRNP:Snurportin complex formation IEA Gallus gallus 1604 R-GGA-191784 https://reactome.org/PathwayBrowser/#/R-GGA-191784 snRNA Cap hypermethylation IEA Gallus gallus 1604 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus 1604 R-HSA-191763 https://reactome.org/PathwayBrowser/#/R-HSA-191763 snRNP:Snurportin complex formation TAS Homo sapiens 1604 R-HSA-191784 https://reactome.org/PathwayBrowser/#/R-HSA-191784 snRNA Cap hypermethylation TAS Homo sapiens 1604 R-HSA-191830 https://reactome.org/PathwayBrowser/#/R-HSA-191830 snRNP nuclear import and release TAS Homo sapiens 1604 R-MMU-191763 https://reactome.org/PathwayBrowser/#/R-MMU-191763 snRNP:Snurportin complex formation IEA Mus musculus 1604 R-MMU-191784 https://reactome.org/PathwayBrowser/#/R-MMU-191784 snRNA Cap hypermethylation IEA Mus musculus 1604 R-MMU-191830 https://reactome.org/PathwayBrowser/#/R-MMU-191830 snRNP nuclear import and release IEA Mus musculus 1604 R-RNO-191763 https://reactome.org/PathwayBrowser/#/R-RNO-191763 snRNP:Snurportin complex formation IEA Rattus norvegicus 1604 R-RNO-191784 https://reactome.org/PathwayBrowser/#/R-RNO-191784 snRNA Cap hypermethylation IEA Rattus norvegicus 1604 R-RNO-191830 https://reactome.org/PathwayBrowser/#/R-RNO-191830 snRNP nuclear import and release IEA Rattus norvegicus 1604 R-SSC-191763 https://reactome.org/PathwayBrowser/#/R-SSC-191763 snRNP:Snurportin complex formation IEA Sus scrofa 1604 R-SSC-191784 https://reactome.org/PathwayBrowser/#/R-SSC-191784 snRNA Cap hypermethylation IEA Sus scrofa 1604 R-SSC-191830 https://reactome.org/PathwayBrowser/#/R-SSC-191830 snRNP nuclear import and release IEA Sus scrofa 16040 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16040 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16040 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16040 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16040 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16040 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16040 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16040 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16040 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16040 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16040 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16040 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16040 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16040 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16040 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16040 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16040 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16040 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16040 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16040 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16047 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 16047 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 16047 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 16047 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 16047 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 16047 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 16047 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 16047 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 16047 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 16047 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 16047 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 16047 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 16047 R-HSA-380008 https://reactome.org/PathwayBrowser/#/R-HSA-380008 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 16047 R-HSA-380233 https://reactome.org/PathwayBrowser/#/R-HSA-380233 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 16047 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 16047 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 16047 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 16047 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 16047 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 16047 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 16057 R-BTA-191382 https://reactome.org/PathwayBrowser/#/R-BTA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Bos taurus 16057 R-BTA-9717834 https://reactome.org/PathwayBrowser/#/R-BTA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Bos taurus 16057 R-CEL-191322 https://reactome.org/PathwayBrowser/#/R-CEL-191322 FDPS dimer transfers IPPP to DMAPP IEA Caenorhabditis elegans 16057 R-CEL-191382 https://reactome.org/PathwayBrowser/#/R-CEL-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Caenorhabditis elegans 16057 R-CFA-191322 https://reactome.org/PathwayBrowser/#/R-CFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Canis familiaris 16057 R-CFA-191382 https://reactome.org/PathwayBrowser/#/R-CFA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Canis familiaris 16057 R-CFA-9717834 https://reactome.org/PathwayBrowser/#/R-CFA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Canis familiaris 16057 R-DDI-191322 https://reactome.org/PathwayBrowser/#/R-DDI-191322 FDPS dimer transfers IPPP to DMAPP IEA Dictyostelium discoideum 16057 R-DDI-191382 https://reactome.org/PathwayBrowser/#/R-DDI-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Dictyostelium discoideum 16057 R-DDI-9717834 https://reactome.org/PathwayBrowser/#/R-DDI-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Dictyostelium discoideum 16057 R-DME-191322 https://reactome.org/PathwayBrowser/#/R-DME-191322 FDPS dimer transfers IPPP to DMAPP IEA Drosophila melanogaster 16057 R-DME-191382 https://reactome.org/PathwayBrowser/#/R-DME-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Drosophila melanogaster 16057 R-DME-9717834 https://reactome.org/PathwayBrowser/#/R-DME-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Drosophila melanogaster 16057 R-DRE-191322 https://reactome.org/PathwayBrowser/#/R-DRE-191322 FDPS dimer transfers IPPP to DMAPP IEA Danio rerio 16057 R-GGA-191322 https://reactome.org/PathwayBrowser/#/R-GGA-191322 FDPS dimer transfers IPPP to DMAPP IEA Gallus gallus 16057 R-GGA-191382 https://reactome.org/PathwayBrowser/#/R-GGA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Gallus gallus 16057 R-GGA-9717834 https://reactome.org/PathwayBrowser/#/R-GGA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Gallus gallus 16057 R-HSA-191322 https://reactome.org/PathwayBrowser/#/R-HSA-191322 FDPS dimer transfers IPPP to DMAPP TAS Homo sapiens 16057 R-HSA-191382 https://reactome.org/PathwayBrowser/#/R-HSA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate TAS Homo sapiens 16057 R-HSA-6784462 https://reactome.org/PathwayBrowser/#/R-HSA-6784462 TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs IEA Homo sapiens 16057 R-HSA-6787567 https://reactome.org/PathwayBrowser/#/R-HSA-6787567 TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) TAS Homo sapiens 16057 R-HSA-9717834 https://reactome.org/PathwayBrowser/#/R-HSA-9717834 GGPS1 hexamer transfers IPPP to DMAPP TAS Homo sapiens 16057 R-MMU-191322 https://reactome.org/PathwayBrowser/#/R-MMU-191322 FDPS dimer transfers IPPP to DMAPP IEA Mus musculus 16057 R-MMU-191382 https://reactome.org/PathwayBrowser/#/R-MMU-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Mus musculus 16057 R-MMU-9717834 https://reactome.org/PathwayBrowser/#/R-MMU-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Mus musculus 16057 R-PFA-191322 https://reactome.org/PathwayBrowser/#/R-PFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Plasmodium falciparum 16057 R-RNO-191322 https://reactome.org/PathwayBrowser/#/R-RNO-191322 FDPS dimer transfers IPPP to DMAPP IEA Rattus norvegicus 16057 R-RNO-191382 https://reactome.org/PathwayBrowser/#/R-RNO-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Rattus norvegicus 16057 R-RNO-9717834 https://reactome.org/PathwayBrowser/#/R-RNO-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Rattus norvegicus 16057 R-SCE-191322 https://reactome.org/PathwayBrowser/#/R-SCE-191322 FDPS dimer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 16057 R-SCE-191382 https://reactome.org/PathwayBrowser/#/R-SCE-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Saccharomyces cerevisiae 16057 R-SCE-6790167 https://reactome.org/PathwayBrowser/#/R-SCE-6790167 MOD5 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) TAS Saccharomyces cerevisiae 16057 R-SCE-9717834 https://reactome.org/PathwayBrowser/#/R-SCE-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 16057 R-SPO-191322 https://reactome.org/PathwayBrowser/#/R-SPO-191322 FDPS dimer transfers IPPP to DMAPP IEA Schizosaccharomyces pombe 16057 R-SPO-191382 https://reactome.org/PathwayBrowser/#/R-SPO-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Schizosaccharomyces pombe 16057 R-SSC-191322 https://reactome.org/PathwayBrowser/#/R-SSC-191322 FDPS dimer transfers IPPP to DMAPP IEA Sus scrofa 16057 R-SSC-191382 https://reactome.org/PathwayBrowser/#/R-SSC-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Sus scrofa 16057 R-SSC-9717834 https://reactome.org/PathwayBrowser/#/R-SSC-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Sus scrofa 16057 R-XTR-191382 https://reactome.org/PathwayBrowser/#/R-XTR-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Xenopus tropicalis 16057 R-XTR-9717834 https://reactome.org/PathwayBrowser/#/R-XTR-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Xenopus tropicalis 16066 R-BTA-2454081 https://reactome.org/PathwayBrowser/#/R-BTA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Bos taurus 16066 R-BTA-2454113 https://reactome.org/PathwayBrowser/#/R-BTA-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Bos taurus 16066 R-BTA-2454118 https://reactome.org/PathwayBrowser/#/R-BTA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Bos taurus 16066 R-BTA-2465924 https://reactome.org/PathwayBrowser/#/R-BTA-2465924 OPN1LW binds 11cRAL IEA Bos taurus 16066 R-BTA-5362721 https://reactome.org/PathwayBrowser/#/R-BTA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Bos taurus 16066 R-BTA-74872 https://reactome.org/PathwayBrowser/#/R-BTA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Bos taurus 16066 R-BTA-8960973 https://reactome.org/PathwayBrowser/#/R-BTA-8960973 RLBP1:11cRAL dissociates IEA Bos taurus 16066 R-BTA-9656891 https://reactome.org/PathwayBrowser/#/R-BTA-9656891 OPN1SW binds 11cRAL IEA Bos taurus 16066 R-BTA-9656893 https://reactome.org/PathwayBrowser/#/R-BTA-9656893 OPN1MW binds 11cRAL IEA Bos taurus 16066 R-CEL-2454118 https://reactome.org/PathwayBrowser/#/R-CEL-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Caenorhabditis elegans 16066 R-CEL-2465924 https://reactome.org/PathwayBrowser/#/R-CEL-2465924 OPN1LW binds 11cRAL IEA Caenorhabditis elegans 16066 R-CEL-5362721 https://reactome.org/PathwayBrowser/#/R-CEL-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Caenorhabditis elegans 16066 R-CEL-9656891 https://reactome.org/PathwayBrowser/#/R-CEL-9656891 OPN1SW binds 11cRAL IEA Caenorhabditis elegans 16066 R-CEL-9656893 https://reactome.org/PathwayBrowser/#/R-CEL-9656893 OPN1MW binds 11cRAL IEA Caenorhabditis elegans 16066 R-CFA-2454081 https://reactome.org/PathwayBrowser/#/R-CFA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Canis familiaris 16066 R-CFA-2454113 https://reactome.org/PathwayBrowser/#/R-CFA-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Canis familiaris 16066 R-CFA-2454118 https://reactome.org/PathwayBrowser/#/R-CFA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Canis familiaris 16066 R-CFA-2465924 https://reactome.org/PathwayBrowser/#/R-CFA-2465924 OPN1LW binds 11cRAL IEA Canis familiaris 16066 R-CFA-5362721 https://reactome.org/PathwayBrowser/#/R-CFA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Canis familiaris 16066 R-CFA-74872 https://reactome.org/PathwayBrowser/#/R-CFA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Canis familiaris 16066 R-CFA-8960973 https://reactome.org/PathwayBrowser/#/R-CFA-8960973 RLBP1:11cRAL dissociates IEA Canis familiaris 16066 R-CFA-9656891 https://reactome.org/PathwayBrowser/#/R-CFA-9656891 OPN1SW binds 11cRAL IEA Canis familiaris 16066 R-CFA-9656893 https://reactome.org/PathwayBrowser/#/R-CFA-9656893 OPN1MW binds 11cRAL IEA Canis familiaris 16066 R-DDI-8960973 https://reactome.org/PathwayBrowser/#/R-DDI-8960973 RLBP1:11cRAL dissociates IEA Dictyostelium discoideum 16066 R-DME-5362721 https://reactome.org/PathwayBrowser/#/R-DME-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 16066 R-DME-74872 https://reactome.org/PathwayBrowser/#/R-DME-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 16066 R-DME-8960973 https://reactome.org/PathwayBrowser/#/R-DME-8960973 RLBP1:11cRAL dissociates IEA Drosophila melanogaster 16066 R-DRE-2454081 https://reactome.org/PathwayBrowser/#/R-DRE-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Danio rerio 16066 R-DRE-2454118 https://reactome.org/PathwayBrowser/#/R-DRE-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Danio rerio 16066 R-DRE-2465924 https://reactome.org/PathwayBrowser/#/R-DRE-2465924 OPN1LW binds 11cRAL IEA Danio rerio 16066 R-DRE-5362721 https://reactome.org/PathwayBrowser/#/R-DRE-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Danio rerio 16066 R-DRE-74872 https://reactome.org/PathwayBrowser/#/R-DRE-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Danio rerio 16066 R-DRE-8960973 https://reactome.org/PathwayBrowser/#/R-DRE-8960973 RLBP1:11cRAL dissociates IEA Danio rerio 16066 R-DRE-9656891 https://reactome.org/PathwayBrowser/#/R-DRE-9656891 OPN1SW binds 11cRAL IEA Danio rerio 16066 R-DRE-9656893 https://reactome.org/PathwayBrowser/#/R-DRE-9656893 OPN1MW binds 11cRAL IEA Danio rerio 16066 R-GGA-2454081 https://reactome.org/PathwayBrowser/#/R-GGA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Gallus gallus 16066 R-GGA-2454113 https://reactome.org/PathwayBrowser/#/R-GGA-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Gallus gallus 16066 R-GGA-2454118 https://reactome.org/PathwayBrowser/#/R-GGA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Gallus gallus 16066 R-GGA-2465924 https://reactome.org/PathwayBrowser/#/R-GGA-2465924 OPN1LW binds 11cRAL IEA Gallus gallus 16066 R-GGA-5362721 https://reactome.org/PathwayBrowser/#/R-GGA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Gallus gallus 16066 R-GGA-74872 https://reactome.org/PathwayBrowser/#/R-GGA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Gallus gallus 16066 R-GGA-8960973 https://reactome.org/PathwayBrowser/#/R-GGA-8960973 RLBP1:11cRAL dissociates IEA Gallus gallus 16066 R-GGA-9656893 https://reactome.org/PathwayBrowser/#/R-GGA-9656893 OPN1MW binds 11cRAL IEA Gallus gallus 16066 R-HSA-2454081 https://reactome.org/PathwayBrowser/#/R-HSA-2454081 RDH5 oxidises 11cROL to 11cRAL TAS Homo sapiens 16066 R-HSA-2454113 https://reactome.org/PathwayBrowser/#/R-HSA-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment TAS Homo sapiens 16066 R-HSA-2454118 https://reactome.org/PathwayBrowser/#/R-HSA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO TAS Homo sapiens 16066 R-HSA-2465921 https://reactome.org/PathwayBrowser/#/R-HSA-2465921 11cRDH oxidises 11cROL to 11cRAL TAS Homo sapiens 16066 R-HSA-2465924 https://reactome.org/PathwayBrowser/#/R-HSA-2465924 OPN1LW binds 11cRAL TAS Homo sapiens 16066 R-HSA-2466706 https://reactome.org/PathwayBrowser/#/R-HSA-2466706 Defective OPN1MW causes DCB and BCM TAS Homo sapiens 16066 R-HSA-2466822 https://reactome.org/PathwayBrowser/#/R-HSA-2466822 Defective OPN1LW causes BCM TAS Homo sapiens 16066 R-HSA-2466834 https://reactome.org/PathwayBrowser/#/R-HSA-2466834 Defective OPN1SW causes tritanopia TAS Homo sapiens 16066 R-HSA-2471641 https://reactome.org/PathwayBrowser/#/R-HSA-2471641 Defective OPN1MW causes COD5 TAS Homo sapiens 16066 R-HSA-2471660 https://reactome.org/PathwayBrowser/#/R-HSA-2471660 Defective OPN1LW causes CBP TAS Homo sapiens 16066 R-HSA-5362721 https://reactome.org/PathwayBrowser/#/R-HSA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL TAS Homo sapiens 16066 R-HSA-74872 https://reactome.org/PathwayBrowser/#/R-HSA-74872 RDH10,11 oxidise 11cROL to 11cRAL TAS Homo sapiens 16066 R-HSA-8960973 https://reactome.org/PathwayBrowser/#/R-HSA-8960973 RLBP1:11cRAL dissociates TAS Homo sapiens 16066 R-HSA-9656891 https://reactome.org/PathwayBrowser/#/R-HSA-9656891 OPN1SW binds 11cRAL TAS Homo sapiens 16066 R-HSA-9656893 https://reactome.org/PathwayBrowser/#/R-HSA-9656893 OPN1MW binds 11cRAL TAS Homo sapiens 16066 R-MMU-2454081 https://reactome.org/PathwayBrowser/#/R-MMU-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Mus musculus 16066 R-MMU-2454113 https://reactome.org/PathwayBrowser/#/R-MMU-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Mus musculus 16066 R-MMU-2454118 https://reactome.org/PathwayBrowser/#/R-MMU-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Mus musculus 16066 R-MMU-2465924 https://reactome.org/PathwayBrowser/#/R-MMU-2465924 OPN1LW binds 11cRAL IEA Mus musculus 16066 R-MMU-5362721 https://reactome.org/PathwayBrowser/#/R-MMU-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Mus musculus 16066 R-MMU-74872 https://reactome.org/PathwayBrowser/#/R-MMU-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Mus musculus 16066 R-MMU-8960973 https://reactome.org/PathwayBrowser/#/R-MMU-8960973 RLBP1:11cRAL dissociates IEA Mus musculus 16066 R-MMU-9656891 https://reactome.org/PathwayBrowser/#/R-MMU-9656891 OPN1SW binds 11cRAL IEA Mus musculus 16066 R-MMU-9656893 https://reactome.org/PathwayBrowser/#/R-MMU-9656893 OPN1MW binds 11cRAL IEA Mus musculus 16066 R-RNO-2454113 https://reactome.org/PathwayBrowser/#/R-RNO-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Rattus norvegicus 16066 R-RNO-2454118 https://reactome.org/PathwayBrowser/#/R-RNO-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Rattus norvegicus 16066 R-RNO-2465924 https://reactome.org/PathwayBrowser/#/R-RNO-2465924 OPN1LW binds 11cRAL IEA Rattus norvegicus 16066 R-RNO-5362721 https://reactome.org/PathwayBrowser/#/R-RNO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 16066 R-RNO-74872 https://reactome.org/PathwayBrowser/#/R-RNO-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 16066 R-RNO-8960973 https://reactome.org/PathwayBrowser/#/R-RNO-8960973 RLBP1:11cRAL dissociates IEA Rattus norvegicus 16066 R-RNO-9656891 https://reactome.org/PathwayBrowser/#/R-RNO-9656891 OPN1SW binds 11cRAL IEA Rattus norvegicus 16066 R-RNO-9656893 https://reactome.org/PathwayBrowser/#/R-RNO-9656893 OPN1MW binds 11cRAL IEA Rattus norvegicus 16066 R-SPO-5362721 https://reactome.org/PathwayBrowser/#/R-SPO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Schizosaccharomyces pombe 16066 R-SSC-2454081 https://reactome.org/PathwayBrowser/#/R-SSC-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Sus scrofa 16066 R-SSC-2454113 https://reactome.org/PathwayBrowser/#/R-SSC-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Sus scrofa 16066 R-SSC-2454118 https://reactome.org/PathwayBrowser/#/R-SSC-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Sus scrofa 16066 R-SSC-2465924 https://reactome.org/PathwayBrowser/#/R-SSC-2465924 OPN1LW binds 11cRAL IEA Sus scrofa 16066 R-SSC-5362721 https://reactome.org/PathwayBrowser/#/R-SSC-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Sus scrofa 16066 R-SSC-74872 https://reactome.org/PathwayBrowser/#/R-SSC-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Sus scrofa 16066 R-SSC-8960973 https://reactome.org/PathwayBrowser/#/R-SSC-8960973 RLBP1:11cRAL dissociates IEA Sus scrofa 16066 R-SSC-9656891 https://reactome.org/PathwayBrowser/#/R-SSC-9656891 OPN1SW binds 11cRAL IEA Sus scrofa 16066 R-SSC-9656893 https://reactome.org/PathwayBrowser/#/R-SSC-9656893 OPN1MW binds 11cRAL IEA Sus scrofa 16066 R-XTR-2454081 https://reactome.org/PathwayBrowser/#/R-XTR-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Xenopus tropicalis 16066 R-XTR-2454113 https://reactome.org/PathwayBrowser/#/R-XTR-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Xenopus tropicalis 16066 R-XTR-2465924 https://reactome.org/PathwayBrowser/#/R-XTR-2465924 OPN1LW binds 11cRAL IEA Xenopus tropicalis 16066 R-XTR-5362721 https://reactome.org/PathwayBrowser/#/R-XTR-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 16066 R-XTR-74872 https://reactome.org/PathwayBrowser/#/R-XTR-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 16066 R-XTR-8960973 https://reactome.org/PathwayBrowser/#/R-XTR-8960973 RLBP1:11cRAL dissociates IEA Xenopus tropicalis 16066 R-XTR-9656891 https://reactome.org/PathwayBrowser/#/R-XTR-9656891 OPN1SW binds 11cRAL IEA Xenopus tropicalis 16066 R-XTR-9656893 https://reactome.org/PathwayBrowser/#/R-XTR-9656893 OPN1MW binds 11cRAL IEA Xenopus tropicalis 16067 R-BTA-1855163 https://reactome.org/PathwayBrowser/#/R-BTA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Bos taurus 16067 R-BTA-1855185 https://reactome.org/PathwayBrowser/#/R-BTA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 16067 R-CEL-1855185 https://reactome.org/PathwayBrowser/#/R-CEL-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 16067 R-CFA-1855163 https://reactome.org/PathwayBrowser/#/R-CFA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Canis familiaris 16067 R-CFA-1855185 https://reactome.org/PathwayBrowser/#/R-CFA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 16067 R-DDI-1855163 https://reactome.org/PathwayBrowser/#/R-DDI-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 16067 R-DDI-1855185 https://reactome.org/PathwayBrowser/#/R-DDI-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 16067 R-DME-1855185 https://reactome.org/PathwayBrowser/#/R-DME-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 16067 R-DRE-1855163 https://reactome.org/PathwayBrowser/#/R-DRE-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Danio rerio 16067 R-DRE-1855185 https://reactome.org/PathwayBrowser/#/R-DRE-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 16067 R-GGA-1855163 https://reactome.org/PathwayBrowser/#/R-GGA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Gallus gallus 16067 R-GGA-1855185 https://reactome.org/PathwayBrowser/#/R-GGA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 16067 R-HSA-1855163 https://reactome.org/PathwayBrowser/#/R-HSA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen TAS Homo sapiens 16067 R-HSA-1855185 https://reactome.org/PathwayBrowser/#/R-HSA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 16067 R-HSA-1855189 https://reactome.org/PathwayBrowser/#/R-HSA-1855189 I(1,4,5,6)P4 transports from the ER lumen to the nucleus TAS Homo sapiens 16067 R-MMU-1855163 https://reactome.org/PathwayBrowser/#/R-MMU-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Mus musculus 16067 R-MMU-1855185 https://reactome.org/PathwayBrowser/#/R-MMU-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 16067 R-PFA-1855185 https://reactome.org/PathwayBrowser/#/R-PFA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 16067 R-RNO-1855163 https://reactome.org/PathwayBrowser/#/R-RNO-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Rattus norvegicus 16067 R-RNO-1855185 https://reactome.org/PathwayBrowser/#/R-RNO-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 16067 R-SSC-1855163 https://reactome.org/PathwayBrowser/#/R-SSC-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Sus scrofa 16067 R-XTR-1855163 https://reactome.org/PathwayBrowser/#/R-XTR-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Xenopus tropicalis 16067 R-XTR-1855185 https://reactome.org/PathwayBrowser/#/R-XTR-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 16068 R-BTA-8953398 https://reactome.org/PathwayBrowser/#/R-BTA-8953398 PIR oxygenates quercetin IEA Bos taurus 16068 R-CFA-8953398 https://reactome.org/PathwayBrowser/#/R-CFA-8953398 PIR oxygenates quercetin IEA Canis familiaris 16068 R-DDI-8953398 https://reactome.org/PathwayBrowser/#/R-DDI-8953398 PIR oxygenates quercetin IEA Dictyostelium discoideum 16068 R-HSA-8953398 https://reactome.org/PathwayBrowser/#/R-HSA-8953398 PIR oxygenates quercetin TAS Homo sapiens 16068 R-MMU-8953398 https://reactome.org/PathwayBrowser/#/R-MMU-8953398 PIR oxygenates quercetin IEA Mus musculus 16068 R-RNO-8953398 https://reactome.org/PathwayBrowser/#/R-RNO-8953398 PIR oxygenates quercetin IEA Rattus norvegicus 16068 R-SSC-8953398 https://reactome.org/PathwayBrowser/#/R-SSC-8953398 PIR oxygenates quercetin IEA Sus scrofa 16068 R-XTR-8953398 https://reactome.org/PathwayBrowser/#/R-XTR-8953398 PIR oxygenates quercetin IEA Xenopus tropicalis 16086 R-HSA-1222583 https://reactome.org/PathwayBrowser/#/R-HSA-1222583 MscR reduces nitrosomycothiol to ammonia TAS Homo sapiens 16086 R-MTU-879266 https://reactome.org/PathwayBrowser/#/R-MTU-879266 mycothiol is oxidized to mycothione TAS Mycobacterium tuberculosis 16086 R-MTU-879322 https://reactome.org/PathwayBrowser/#/R-MTU-879322 mycothione is reduced to mycothiol TAS Mycobacterium tuberculosis 16091 R-BTA-4419979 https://reactome.org/PathwayBrowser/#/R-BTA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Bos taurus 16091 R-BTA-446195 https://reactome.org/PathwayBrowser/#/R-BTA-446195 DOLK phosphorylates DCHOL to DOLP IEA Bos taurus 16091 R-CEL-4419979 https://reactome.org/PathwayBrowser/#/R-CEL-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Caenorhabditis elegans 16091 R-CFA-4419979 https://reactome.org/PathwayBrowser/#/R-CFA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Canis familiaris 16091 R-CFA-446195 https://reactome.org/PathwayBrowser/#/R-CFA-446195 DOLK phosphorylates DCHOL to DOLP IEA Canis familiaris 16091 R-DDI-4419979 https://reactome.org/PathwayBrowser/#/R-DDI-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Dictyostelium discoideum 16091 R-DDI-446195 https://reactome.org/PathwayBrowser/#/R-DDI-446195 DOLK phosphorylates DCHOL to DOLP IEA Dictyostelium discoideum 16091 R-DME-4419979 https://reactome.org/PathwayBrowser/#/R-DME-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Drosophila melanogaster 16091 R-DME-446195 https://reactome.org/PathwayBrowser/#/R-DME-446195 DOLK phosphorylates DCHOL to DOLP IEA Drosophila melanogaster 16091 R-DRE-4419979 https://reactome.org/PathwayBrowser/#/R-DRE-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Danio rerio 16091 R-DRE-446195 https://reactome.org/PathwayBrowser/#/R-DRE-446195 DOLK phosphorylates DCHOL to DOLP IEA Danio rerio 16091 R-GGA-4419979 https://reactome.org/PathwayBrowser/#/R-GGA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Gallus gallus 16091 R-GGA-446195 https://reactome.org/PathwayBrowser/#/R-GGA-446195 DOLK phosphorylates DCHOL to DOLP IEA Gallus gallus 16091 R-HSA-4419979 https://reactome.org/PathwayBrowser/#/R-HSA-4419979 SRD5A3 reduces pPNOL to DCHOL TAS Homo sapiens 16091 R-HSA-446195 https://reactome.org/PathwayBrowser/#/R-HSA-446195 DOLK phosphorylates DCHOL to DOLP TAS Homo sapiens 16091 R-HSA-4755600 https://reactome.org/PathwayBrowser/#/R-HSA-4755600 Defective DOLK does not phosphorylate DCHOL TAS Homo sapiens 16091 R-MMU-4419979 https://reactome.org/PathwayBrowser/#/R-MMU-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Mus musculus 16091 R-MMU-446195 https://reactome.org/PathwayBrowser/#/R-MMU-446195 DOLK phosphorylates DCHOL to DOLP IEA Mus musculus 16091 R-PFA-4419979 https://reactome.org/PathwayBrowser/#/R-PFA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Plasmodium falciparum 16091 R-RNO-4419979 https://reactome.org/PathwayBrowser/#/R-RNO-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Rattus norvegicus 16091 R-RNO-446195 https://reactome.org/PathwayBrowser/#/R-RNO-446195 DOLK phosphorylates DCHOL to DOLP IEA Rattus norvegicus 16091 R-SCE-4419979 https://reactome.org/PathwayBrowser/#/R-SCE-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Saccharomyces cerevisiae 16091 R-SCE-446195 https://reactome.org/PathwayBrowser/#/R-SCE-446195 DOLK phosphorylates DCHOL to DOLP IEA Saccharomyces cerevisiae 16091 R-SPO-4419979 https://reactome.org/PathwayBrowser/#/R-SPO-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Schizosaccharomyces pombe 16091 R-SPO-446195 https://reactome.org/PathwayBrowser/#/R-SPO-446195 DOLK phosphorylates DCHOL to DOLP IEA Schizosaccharomyces pombe 16091 R-SSC-4419979 https://reactome.org/PathwayBrowser/#/R-SSC-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Sus scrofa 16091 R-SSC-446195 https://reactome.org/PathwayBrowser/#/R-SSC-446195 DOLK phosphorylates DCHOL to DOLP IEA Sus scrofa 16091 R-XTR-4419979 https://reactome.org/PathwayBrowser/#/R-XTR-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Xenopus tropicalis 16091 R-XTR-446195 https://reactome.org/PathwayBrowser/#/R-XTR-446195 DOLK phosphorylates DCHOL to DOLP IEA Xenopus tropicalis 16095 R-BTA-1497869 https://reactome.org/PathwayBrowser/#/R-BTA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Bos taurus 16095 R-CFA-1497869 https://reactome.org/PathwayBrowser/#/R-CFA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Canis familiaris 16095 R-DDI-1497869 https://reactome.org/PathwayBrowser/#/R-DDI-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Dictyostelium discoideum 16095 R-DME-1497869 https://reactome.org/PathwayBrowser/#/R-DME-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Drosophila melanogaster 16095 R-DRE-1497869 https://reactome.org/PathwayBrowser/#/R-DRE-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Danio rerio 16095 R-GGA-1497869 https://reactome.org/PathwayBrowser/#/R-GGA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Gallus gallus 16095 R-HSA-1497869 https://reactome.org/PathwayBrowser/#/R-HSA-1497869 Salvage - Sepiapterin is reduced to BH2 TAS Homo sapiens 16095 R-HSA-9693722 https://reactome.org/PathwayBrowser/#/R-HSA-9693722 Unknown sepiapterin synthase transforms PTHP to sepiapterin TAS Homo sapiens 16095 R-MMU-1497869 https://reactome.org/PathwayBrowser/#/R-MMU-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Mus musculus 16095 R-RNO-1497869 https://reactome.org/PathwayBrowser/#/R-RNO-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Rattus norvegicus 16095 R-SSC-1497869 https://reactome.org/PathwayBrowser/#/R-SSC-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Sus scrofa 16095 R-XTR-1497869 https://reactome.org/PathwayBrowser/#/R-XTR-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Xenopus tropicalis 16113 R-BTA-1454928 https://reactome.org/PathwayBrowser/#/R-BTA-1454928 ABCG4 may mediate cholesterol efflux IEA Bos taurus 16113 R-BTA-171059 https://reactome.org/PathwayBrowser/#/R-BTA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Bos taurus 16113 R-BTA-171106 https://reactome.org/PathwayBrowser/#/R-BTA-171106 LDLR:LDL complex => LDLR + LDL IEA Bos taurus 16113 R-BTA-171122 https://reactome.org/PathwayBrowser/#/R-BTA-171122 LDL + LDLR => LDL:LDLR complex IEA Bos taurus 16113 R-BTA-171141 https://reactome.org/PathwayBrowser/#/R-BTA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Bos taurus 16113 R-BTA-174587 https://reactome.org/PathwayBrowser/#/R-BTA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Bos taurus 16113 R-BTA-174657 https://reactome.org/PathwayBrowser/#/R-BTA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Bos taurus 16113 R-BTA-174660 https://reactome.org/PathwayBrowser/#/R-BTA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Bos taurus 16113 R-BTA-174690 https://reactome.org/PathwayBrowser/#/R-BTA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Bos taurus 16113 R-BTA-174706 https://reactome.org/PathwayBrowser/#/R-BTA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Bos taurus 16113 R-BTA-174739 https://reactome.org/PathwayBrowser/#/R-BTA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Bos taurus 16113 R-BTA-174741 https://reactome.org/PathwayBrowser/#/R-BTA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Bos taurus 16113 R-BTA-174757 https://reactome.org/PathwayBrowser/#/R-BTA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Bos taurus 16113 R-BTA-176609 https://reactome.org/PathwayBrowser/#/R-BTA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Bos taurus 16113 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 16113 R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 16113 R-BTA-192123 https://reactome.org/PathwayBrowser/#/R-BTA-192123 CYP27A1 27-hydroxylates CHOL IEA Bos taurus 16113 R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 16113 R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 16113 R-BTA-196086 https://reactome.org/PathwayBrowser/#/R-BTA-196086 Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane IEA Bos taurus 16113 R-BTA-196126 https://reactome.org/PathwayBrowser/#/R-BTA-196126 CHOL translocates from cytosol to mitochondrial intermembrane space IEA Bos taurus 16113 R-BTA-196417 https://reactome.org/PathwayBrowser/#/R-BTA-196417 Reduction of desmosterol to cholesterol IEA Bos taurus 16113 R-BTA-203130 https://reactome.org/PathwayBrowser/#/R-BTA-203130 OLR1 binds to oxidized LDL IEA Bos taurus 16113 R-BTA-216723 https://reactome.org/PathwayBrowser/#/R-BTA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Bos taurus 16113 R-BTA-216756 https://reactome.org/PathwayBrowser/#/R-BTA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Bos taurus 16113 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 16113 R-BTA-2187332 https://reactome.org/PathwayBrowser/#/R-BTA-2187332 Cytosolic CMs translocate to extracellular region IEA Bos taurus 16113 R-BTA-2197646 https://reactome.org/PathwayBrowser/#/R-BTA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Bos taurus 16113 R-BTA-2197770 https://reactome.org/PathwayBrowser/#/R-BTA-2197770 STAB1 (FEEL-1) binds ligands IEA Bos taurus 16113 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 16113 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 16113 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 16113 R-BTA-2247513 https://reactome.org/PathwayBrowser/#/R-BTA-2247513 STAB1:ligand is endocytosed IEA Bos taurus 16113 R-BTA-2395764 https://reactome.org/PathwayBrowser/#/R-BTA-2395764 atREs binds to nascent CM IEA Bos taurus 16113 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 16113 R-BTA-2395784 https://reactome.org/PathwayBrowser/#/R-BTA-2395784 Nascent CMs transform into mature CMs IEA Bos taurus 16113 R-BTA-2404131 https://reactome.org/PathwayBrowser/#/R-BTA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Bos taurus 16113 R-BTA-2423785 https://reactome.org/PathwayBrowser/#/R-BTA-2423785 CR:atREs binds apoE and HSPG IEA Bos taurus 16113 R-BTA-2512800 https://reactome.org/PathwayBrowser/#/R-BTA-2512800 SCARB1:ligand is endocytosed IEA Bos taurus 16113 R-BTA-264678 https://reactome.org/PathwayBrowser/#/R-BTA-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Bos taurus 16113 R-BTA-264689 https://reactome.org/PathwayBrowser/#/R-BTA-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Bos taurus 16113 R-BTA-264695 https://reactome.org/PathwayBrowser/#/R-BTA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Bos taurus 16113 R-BTA-265783 https://reactome.org/PathwayBrowser/#/R-BTA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Bos taurus 16113 R-BTA-266082 https://reactome.org/PathwayBrowser/#/R-BTA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Bos taurus 16113 R-BTA-266089 https://reactome.org/PathwayBrowser/#/R-BTA-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Bos taurus 16113 R-BTA-266299 https://reactome.org/PathwayBrowser/#/R-BTA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Bos taurus 16113 R-BTA-266303 https://reactome.org/PathwayBrowser/#/R-BTA-266303 Spherical HDL binds C and E apolipoproteins IEA Bos taurus 16113 R-BTA-266310 https://reactome.org/PathwayBrowser/#/R-BTA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Bos taurus 16113 R-BTA-266315 https://reactome.org/PathwayBrowser/#/R-BTA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Bos taurus 16113 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 16113 R-BTA-349637 https://reactome.org/PathwayBrowser/#/R-BTA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Bos taurus 16113 R-BTA-349638 https://reactome.org/PathwayBrowser/#/R-BTA-349638 Disassembly of SR-BI-bound spherical HDL IEA Bos taurus 16113 R-BTA-349657 https://reactome.org/PathwayBrowser/#/R-BTA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Bos taurus 16113 R-BTA-432121 https://reactome.org/PathwayBrowser/#/R-BTA-432121 LDL binds to LRP8 IEA Bos taurus 16113 R-BTA-432129 https://reactome.org/PathwayBrowser/#/R-BTA-432129 FGR binds and phosphorylates LRP8 IEA Bos taurus 16113 R-BTA-435244 https://reactome.org/PathwayBrowser/#/R-BTA-435244 PECAM1 is phosphorylated IEA Bos taurus 16113 R-BTA-5250531 https://reactome.org/PathwayBrowser/#/R-BTA-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Bos taurus 16113 R-BTA-5358340 https://reactome.org/PathwayBrowser/#/R-BTA-5358340 Autoproteolytic cleavage of Hh precursors IEA Bos taurus 16113 R-BTA-6807055 https://reactome.org/PathwayBrowser/#/R-BTA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Bos taurus 16113 R-BTA-6810937 https://reactome.org/PathwayBrowser/#/R-BTA-6810937 Lamellar bodies bind the early cornified envelope IEA Bos taurus 16113 R-BTA-6813720 https://reactome.org/PathwayBrowser/#/R-BTA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Bos taurus 16113 R-BTA-6814387 https://reactome.org/PathwayBrowser/#/R-BTA-6814387 CASP14 cleaves filaggrin IEA Bos taurus 16113 R-BTA-6814734 https://reactome.org/PathwayBrowser/#/R-BTA-6814734 CDSN binds the cornified envelope IEA Bos taurus 16113 R-BTA-6814764 https://reactome.org/PathwayBrowser/#/R-BTA-6814764 Plasma membrane resorption IEA Bos taurus 16113 R-BTA-8848053 https://reactome.org/PathwayBrowser/#/R-BTA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Bos taurus 16113 R-BTA-8858252 https://reactome.org/PathwayBrowser/#/R-BTA-8858252 HDLBP binds HDL IEA Bos taurus 16113 R-BTA-8863471 https://reactome.org/PathwayBrowser/#/R-BTA-8863471 LDLR is bound by DAB2 and ARH IEA Bos taurus 16113 R-BTA-8865667 https://reactome.org/PathwayBrowser/#/R-BTA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Bos taurus 16113 R-BTA-8866304 https://reactome.org/PathwayBrowser/#/R-BTA-8866304 pre-VLDL binds lipids to form VLDL IEA Bos taurus 16113 R-BTA-8866327 https://reactome.org/PathwayBrowser/#/R-BTA-8866327 VLDL translocates from SER lumen to extracellular region IEA Bos taurus 16113 R-BTA-8867754 https://reactome.org/PathwayBrowser/#/R-BTA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Bos taurus 16113 R-BTA-8867756 https://reactome.org/PathwayBrowser/#/R-BTA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Bos taurus 16113 R-BTA-8868071 https://reactome.org/PathwayBrowser/#/R-BTA-8868071 Clathrin recruits PIK3C2A IEA Bos taurus 16113 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 16113 R-BTA-8868230 https://reactome.org/PathwayBrowser/#/R-BTA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Bos taurus 16113 R-BTA-8868236 https://reactome.org/PathwayBrowser/#/R-BTA-8868236 BAR domain proteins recruit dynamin IEA Bos taurus 16113 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 16113 R-BTA-8868651 https://reactome.org/PathwayBrowser/#/R-BTA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Bos taurus 16113 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 16113 R-BTA-8868659 https://reactome.org/PathwayBrowser/#/R-BTA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Bos taurus 16113 R-BTA-8868660 https://reactome.org/PathwayBrowser/#/R-BTA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Bos taurus 16113 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 16113 R-BTA-8869667 https://reactome.org/PathwayBrowser/#/R-BTA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Bos taurus 16113 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 16113 R-BTA-8871194 https://reactome.org/PathwayBrowser/#/R-BTA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Bos taurus 16113 R-BTA-8876366 https://reactome.org/PathwayBrowser/#/R-BTA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Bos taurus 16113 R-BTA-8876472 https://reactome.org/PathwayBrowser/#/R-BTA-8876472 NPC2 binds CHOL IEA Bos taurus 16113 R-BTA-8876484 https://reactome.org/PathwayBrowser/#/R-BTA-8876484 NPC2 transfers CHOL to NPC1 IEA Bos taurus 16113 R-BTA-8876485 https://reactome.org/PathwayBrowser/#/R-BTA-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Bos taurus 16113 R-BTA-8876696 https://reactome.org/PathwayBrowser/#/R-BTA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Bos taurus 16113 R-BTA-8937442 https://reactome.org/PathwayBrowser/#/R-BTA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Bos taurus 16113 R-BTA-8948034 https://reactome.org/PathwayBrowser/#/R-BTA-8948034 FGR binds LDL:LRP8 IEA Bos taurus 16113 R-BTA-9707586 https://reactome.org/PathwayBrowser/#/R-BTA-9707586 FeHM oxidises LDL,HDL IEA Bos taurus 16113 R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 16113 R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 16113 R-CEL-196417 https://reactome.org/PathwayBrowser/#/R-CEL-196417 Reduction of desmosterol to cholesterol IEA Caenorhabditis elegans 16113 R-CEL-264695 https://reactome.org/PathwayBrowser/#/R-CEL-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Caenorhabditis elegans 16113 R-CEL-265783 https://reactome.org/PathwayBrowser/#/R-CEL-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Caenorhabditis elegans 16113 R-CEL-5250531 https://reactome.org/PathwayBrowser/#/R-CEL-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Caenorhabditis elegans 16113 R-CEL-6807055 https://reactome.org/PathwayBrowser/#/R-CEL-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Caenorhabditis elegans 16113 R-CEL-6813720 https://reactome.org/PathwayBrowser/#/R-CEL-6813720 NCEH1 hydrolyzes cholesterol esters IEA Caenorhabditis elegans 16113 R-CEL-8876472 https://reactome.org/PathwayBrowser/#/R-CEL-8876472 NPC2 binds CHOL IEA Caenorhabditis elegans 16113 R-CEL-8876484 https://reactome.org/PathwayBrowser/#/R-CEL-8876484 NPC2 transfers CHOL to NPC1 IEA Caenorhabditis elegans 16113 R-CEL-8876485 https://reactome.org/PathwayBrowser/#/R-CEL-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Caenorhabditis elegans 16113 R-CEL-8876696 https://reactome.org/PathwayBrowser/#/R-CEL-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Caenorhabditis elegans 16113 R-CEL-8937442 https://reactome.org/PathwayBrowser/#/R-CEL-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Caenorhabditis elegans 16113 R-CEL-8951850 https://reactome.org/PathwayBrowser/#/R-CEL-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Caenorhabditis elegans 16113 R-CFA-1454928 https://reactome.org/PathwayBrowser/#/R-CFA-1454928 ABCG4 may mediate cholesterol efflux IEA Canis familiaris 16113 R-CFA-171059 https://reactome.org/PathwayBrowser/#/R-CFA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Canis familiaris 16113 R-CFA-171106 https://reactome.org/PathwayBrowser/#/R-CFA-171106 LDLR:LDL complex => LDLR + LDL IEA Canis familiaris 16113 R-CFA-171122 https://reactome.org/PathwayBrowser/#/R-CFA-171122 LDL + LDLR => LDL:LDLR complex IEA Canis familiaris 16113 R-CFA-171141 https://reactome.org/PathwayBrowser/#/R-CFA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Canis familiaris 16113 R-CFA-174587 https://reactome.org/PathwayBrowser/#/R-CFA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Canis familiaris 16113 R-CFA-174657 https://reactome.org/PathwayBrowser/#/R-CFA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Canis familiaris 16113 R-CFA-174660 https://reactome.org/PathwayBrowser/#/R-CFA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Canis familiaris 16113 R-CFA-174690 https://reactome.org/PathwayBrowser/#/R-CFA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Canis familiaris 16113 R-CFA-174706 https://reactome.org/PathwayBrowser/#/R-CFA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Canis familiaris 16113 R-CFA-174739 https://reactome.org/PathwayBrowser/#/R-CFA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Canis familiaris 16113 R-CFA-174741 https://reactome.org/PathwayBrowser/#/R-CFA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Canis familiaris 16113 R-CFA-174757 https://reactome.org/PathwayBrowser/#/R-CFA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Canis familiaris 16113 R-CFA-176609 https://reactome.org/PathwayBrowser/#/R-CFA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Canis familiaris 16113 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 16113 R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 16113 R-CFA-192123 https://reactome.org/PathwayBrowser/#/R-CFA-192123 CYP27A1 27-hydroxylates CHOL IEA Canis familiaris 16113 R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 16113 R-CFA-196086 https://reactome.org/PathwayBrowser/#/R-CFA-196086 Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane IEA Canis familiaris 16113 R-CFA-196126 https://reactome.org/PathwayBrowser/#/R-CFA-196126 CHOL translocates from cytosol to mitochondrial intermembrane space IEA Canis familiaris 16113 R-CFA-196417 https://reactome.org/PathwayBrowser/#/R-CFA-196417 Reduction of desmosterol to cholesterol IEA Canis familiaris 16113 R-CFA-203130 https://reactome.org/PathwayBrowser/#/R-CFA-203130 OLR1 binds to oxidized LDL IEA Canis familiaris 16113 R-CFA-216723 https://reactome.org/PathwayBrowser/#/R-CFA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Canis familiaris 16113 R-CFA-216756 https://reactome.org/PathwayBrowser/#/R-CFA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Canis familiaris 16113 R-CFA-2187332 https://reactome.org/PathwayBrowser/#/R-CFA-2187332 Cytosolic CMs translocate to extracellular region IEA Canis familiaris 16113 R-CFA-2197646 https://reactome.org/PathwayBrowser/#/R-CFA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Canis familiaris 16113 R-CFA-2197770 https://reactome.org/PathwayBrowser/#/R-CFA-2197770 STAB1 (FEEL-1) binds ligands IEA Canis familiaris 16113 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 16113 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 16113 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 16113 R-CFA-2247513 https://reactome.org/PathwayBrowser/#/R-CFA-2247513 STAB1:ligand is endocytosed IEA Canis familiaris 16113 R-CFA-2395764 https://reactome.org/PathwayBrowser/#/R-CFA-2395764 atREs binds to nascent CM IEA Canis familiaris 16113 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 16113 R-CFA-2395784 https://reactome.org/PathwayBrowser/#/R-CFA-2395784 Nascent CMs transform into mature CMs IEA Canis familiaris 16113 R-CFA-2404131 https://reactome.org/PathwayBrowser/#/R-CFA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Canis familiaris 16113 R-CFA-2423785 https://reactome.org/PathwayBrowser/#/R-CFA-2423785 CR:atREs binds apoE and HSPG IEA Canis familiaris 16113 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 16113 R-CFA-2512800 https://reactome.org/PathwayBrowser/#/R-CFA-2512800 SCARB1:ligand is endocytosed IEA Canis familiaris 16113 R-CFA-265529 https://reactome.org/PathwayBrowser/#/R-CFA-265529 NPC1L1-mediated cholesterol uptake TAS Canis familiaris 16113 R-CFA-265783 https://reactome.org/PathwayBrowser/#/R-CFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Canis familiaris 16113 R-CFA-266082 https://reactome.org/PathwayBrowser/#/R-CFA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Canis familiaris 16113 R-CFA-266089 https://reactome.org/PathwayBrowser/#/R-CFA-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Canis familiaris 16113 R-CFA-266299 https://reactome.org/PathwayBrowser/#/R-CFA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Canis familiaris 16113 R-CFA-266303 https://reactome.org/PathwayBrowser/#/R-CFA-266303 Spherical HDL binds C and E apolipoproteins IEA Canis familiaris 16113 R-CFA-349637 https://reactome.org/PathwayBrowser/#/R-CFA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Canis familiaris 16113 R-CFA-349638 https://reactome.org/PathwayBrowser/#/R-CFA-349638 Disassembly of SR-BI-bound spherical HDL IEA Canis familiaris 16113 R-CFA-349657 https://reactome.org/PathwayBrowser/#/R-CFA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Canis familiaris 16113 R-CFA-432121 https://reactome.org/PathwayBrowser/#/R-CFA-432121 LDL binds to LRP8 IEA Canis familiaris 16113 R-CFA-432129 https://reactome.org/PathwayBrowser/#/R-CFA-432129 FGR binds and phosphorylates LRP8 IEA Canis familiaris 16113 R-CFA-435244 https://reactome.org/PathwayBrowser/#/R-CFA-435244 PECAM1 is phosphorylated IEA Canis familiaris 16113 R-CFA-5250531 https://reactome.org/PathwayBrowser/#/R-CFA-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Canis familiaris 16113 R-CFA-5358340 https://reactome.org/PathwayBrowser/#/R-CFA-5358340 Autoproteolytic cleavage of Hh precursors IEA Canis familiaris 16113 R-CFA-6807055 https://reactome.org/PathwayBrowser/#/R-CFA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Canis familiaris 16113 R-CFA-6810937 https://reactome.org/PathwayBrowser/#/R-CFA-6810937 Lamellar bodies bind the early cornified envelope IEA Canis familiaris 16113 R-CFA-6813720 https://reactome.org/PathwayBrowser/#/R-CFA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Canis familiaris 16113 R-CFA-6814387 https://reactome.org/PathwayBrowser/#/R-CFA-6814387 CASP14 cleaves filaggrin IEA Canis familiaris 16113 R-CFA-6814734 https://reactome.org/PathwayBrowser/#/R-CFA-6814734 CDSN binds the cornified envelope IEA Canis familiaris 16113 R-CFA-6814764 https://reactome.org/PathwayBrowser/#/R-CFA-6814764 Plasma membrane resorption IEA Canis familiaris 16113 R-CFA-8848053 https://reactome.org/PathwayBrowser/#/R-CFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Canis familiaris 16113 R-CFA-8854408 https://reactome.org/PathwayBrowser/#/R-CFA-8854408 APOBR dimer binds VLDLs IEA Canis familiaris 16113 R-CFA-8854462 https://reactome.org/PathwayBrowser/#/R-CFA-8854462 VLDLR binds VLDL IEA Canis familiaris 16113 R-CFA-8858252 https://reactome.org/PathwayBrowser/#/R-CFA-8858252 HDLBP binds HDL IEA Canis familiaris 16113 R-CFA-8863471 https://reactome.org/PathwayBrowser/#/R-CFA-8863471 LDLR is bound by DAB2 and ARH IEA Canis familiaris 16113 R-CFA-8865667 https://reactome.org/PathwayBrowser/#/R-CFA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Canis familiaris 16113 R-CFA-8866304 https://reactome.org/PathwayBrowser/#/R-CFA-8866304 pre-VLDL binds lipids to form VLDL IEA Canis familiaris 16113 R-CFA-8866321 https://reactome.org/PathwayBrowser/#/R-CFA-8866321 VLDL binds APOC1 and APOC4 IEA Canis familiaris 16113 R-CFA-8866327 https://reactome.org/PathwayBrowser/#/R-CFA-8866327 VLDL translocates from SER lumen to extracellular region IEA Canis familiaris 16113 R-CFA-8867754 https://reactome.org/PathwayBrowser/#/R-CFA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Canis familiaris 16113 R-CFA-8867756 https://reactome.org/PathwayBrowser/#/R-CFA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Canis familiaris 16113 R-CFA-8868071 https://reactome.org/PathwayBrowser/#/R-CFA-8868071 Clathrin recruits PIK3C2A IEA Canis familiaris 16113 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 16113 R-CFA-8868230 https://reactome.org/PathwayBrowser/#/R-CFA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Canis familiaris 16113 R-CFA-8868236 https://reactome.org/PathwayBrowser/#/R-CFA-8868236 BAR domain proteins recruit dynamin IEA Canis familiaris 16113 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 16113 R-CFA-8868651 https://reactome.org/PathwayBrowser/#/R-CFA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Canis familiaris 16113 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 16113 R-CFA-8868659 https://reactome.org/PathwayBrowser/#/R-CFA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Canis familiaris 16113 R-CFA-8868660 https://reactome.org/PathwayBrowser/#/R-CFA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Canis familiaris 16113 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 16113 R-CFA-8871193 https://reactome.org/PathwayBrowser/#/R-CFA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Canis familiaris 16113 R-CFA-8871194 https://reactome.org/PathwayBrowser/#/R-CFA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Canis familiaris 16113 R-CFA-8876366 https://reactome.org/PathwayBrowser/#/R-CFA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Canis familiaris 16113 R-CFA-8876472 https://reactome.org/PathwayBrowser/#/R-CFA-8876472 NPC2 binds CHOL IEA Canis familiaris 16113 R-CFA-8876484 https://reactome.org/PathwayBrowser/#/R-CFA-8876484 NPC2 transfers CHOL to NPC1 IEA Canis familiaris 16113 R-CFA-8876485 https://reactome.org/PathwayBrowser/#/R-CFA-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Canis familiaris 16113 R-CFA-8876696 https://reactome.org/PathwayBrowser/#/R-CFA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Canis familiaris 16113 R-CFA-8948034 https://reactome.org/PathwayBrowser/#/R-CFA-8948034 FGR binds LDL:LRP8 IEA Canis familiaris 16113 R-CFA-8951850 https://reactome.org/PathwayBrowser/#/R-CFA-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Canis familiaris 16113 R-CFA-9707586 https://reactome.org/PathwayBrowser/#/R-CFA-9707586 FeHM oxidises LDL,HDL IEA Canis familiaris 16113 R-DDI-1369028 https://reactome.org/PathwayBrowser/#/R-DDI-1369028 ABCAs mediate lipid efflux IEA Dictyostelium discoideum 16113 R-DDI-1369052 https://reactome.org/PathwayBrowser/#/R-DDI-1369052 ABCAs mediate lipid influx IEA Dictyostelium discoideum 16113 R-DDI-1454928 https://reactome.org/PathwayBrowser/#/R-DDI-1454928 ABCG4 may mediate cholesterol efflux IEA Dictyostelium discoideum 16113 R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 16113 R-DDI-265783 https://reactome.org/PathwayBrowser/#/R-DDI-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Dictyostelium discoideum 16113 R-DDI-266082 https://reactome.org/PathwayBrowser/#/R-DDI-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Dictyostelium discoideum 16113 R-DDI-5250531 https://reactome.org/PathwayBrowser/#/R-DDI-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Dictyostelium discoideum 16113 R-DDI-6813720 https://reactome.org/PathwayBrowser/#/R-DDI-6813720 NCEH1 hydrolyzes cholesterol esters IEA Dictyostelium discoideum 16113 R-DDI-8848053 https://reactome.org/PathwayBrowser/#/R-DDI-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Dictyostelium discoideum 16113 R-DDI-8876472 https://reactome.org/PathwayBrowser/#/R-DDI-8876472 NPC2 binds CHOL IEA Dictyostelium discoideum 16113 R-DDI-8876484 https://reactome.org/PathwayBrowser/#/R-DDI-8876484 NPC2 transfers CHOL to NPC1 IEA Dictyostelium discoideum 16113 R-DDI-8876485 https://reactome.org/PathwayBrowser/#/R-DDI-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Dictyostelium discoideum 16113 R-DDI-8937442 https://reactome.org/PathwayBrowser/#/R-DDI-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Dictyostelium discoideum 16113 R-DME-1454928 https://reactome.org/PathwayBrowser/#/R-DME-1454928 ABCG4 may mediate cholesterol efflux IEA Drosophila melanogaster 16113 R-DME-176609 https://reactome.org/PathwayBrowser/#/R-DME-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Drosophila melanogaster 16113 R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 16113 R-DME-209313 https://reactome.org/PathwayBrowser/#/R-DME-209313 Autocleavage of HH TAS Drosophila melanogaster 16113 R-DME-264695 https://reactome.org/PathwayBrowser/#/R-DME-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Drosophila melanogaster 16113 R-DME-265783 https://reactome.org/PathwayBrowser/#/R-DME-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Drosophila melanogaster 16113 R-DME-266082 https://reactome.org/PathwayBrowser/#/R-DME-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Drosophila melanogaster 16113 R-DME-5250531 https://reactome.org/PathwayBrowser/#/R-DME-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Drosophila melanogaster 16113 R-DME-5358340 https://reactome.org/PathwayBrowser/#/R-DME-5358340 Autoproteolytic cleavage of Hh precursors IEA Drosophila melanogaster 16113 R-DME-8876472 https://reactome.org/PathwayBrowser/#/R-DME-8876472 NPC2 binds CHOL IEA Drosophila melanogaster 16113 R-DME-8876484 https://reactome.org/PathwayBrowser/#/R-DME-8876484 NPC2 transfers CHOL to NPC1 IEA Drosophila melanogaster 16113 R-DME-8876485 https://reactome.org/PathwayBrowser/#/R-DME-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Drosophila melanogaster 16113 R-DME-8876696 https://reactome.org/PathwayBrowser/#/R-DME-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Drosophila melanogaster 16113 R-DME-8937442 https://reactome.org/PathwayBrowser/#/R-DME-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Drosophila melanogaster 16113 R-DME-8951850 https://reactome.org/PathwayBrowser/#/R-DME-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Drosophila melanogaster 16113 R-DRE-1454928 https://reactome.org/PathwayBrowser/#/R-DRE-1454928 ABCG4 may mediate cholesterol efflux IEA Danio rerio 16113 R-DRE-176609 https://reactome.org/PathwayBrowser/#/R-DRE-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Danio rerio 16113 R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 16113 R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 16113 R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 16113 R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 16113 R-DRE-196086 https://reactome.org/PathwayBrowser/#/R-DRE-196086 Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane IEA Danio rerio 16113 R-DRE-196126 https://reactome.org/PathwayBrowser/#/R-DRE-196126 CHOL translocates from cytosol to mitochondrial intermembrane space IEA Danio rerio 16113 R-DRE-196417 https://reactome.org/PathwayBrowser/#/R-DRE-196417 Reduction of desmosterol to cholesterol IEA Danio rerio 16113 R-DRE-216723 https://reactome.org/PathwayBrowser/#/R-DRE-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Danio rerio 16113 R-DRE-216756 https://reactome.org/PathwayBrowser/#/R-DRE-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Danio rerio 16113 R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 16113 R-DRE-266082 https://reactome.org/PathwayBrowser/#/R-DRE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Danio rerio 16113 R-DRE-266089 https://reactome.org/PathwayBrowser/#/R-DRE-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Danio rerio 16113 R-DRE-266299 https://reactome.org/PathwayBrowser/#/R-DRE-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Danio rerio 16113 R-DRE-349657 https://reactome.org/PathwayBrowser/#/R-DRE-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Danio rerio 16113 R-DRE-5250531 https://reactome.org/PathwayBrowser/#/R-DRE-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Danio rerio 16113 R-DRE-5358340 https://reactome.org/PathwayBrowser/#/R-DRE-5358340 Autoproteolytic cleavage of Hh precursors IEA Danio rerio 16113 R-DRE-6807055 https://reactome.org/PathwayBrowser/#/R-DRE-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Danio rerio 16113 R-DRE-6813720 https://reactome.org/PathwayBrowser/#/R-DRE-6813720 NCEH1 hydrolyzes cholesterol esters IEA Danio rerio 16113 R-DRE-8876472 https://reactome.org/PathwayBrowser/#/R-DRE-8876472 NPC2 binds CHOL IEA Danio rerio 16113 R-DRE-8876696 https://reactome.org/PathwayBrowser/#/R-DRE-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Danio rerio 16113 R-DRE-8937442 https://reactome.org/PathwayBrowser/#/R-DRE-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Danio rerio 16113 R-GGA-1369028 https://reactome.org/PathwayBrowser/#/R-GGA-1369028 ABCAs mediate lipid efflux IEA Gallus gallus 16113 R-GGA-1369052 https://reactome.org/PathwayBrowser/#/R-GGA-1369052 ABCAs mediate lipid influx IEA Gallus gallus 16113 R-GGA-1454928 https://reactome.org/PathwayBrowser/#/R-GGA-1454928 ABCG4 may mediate cholesterol efflux IEA Gallus gallus 16113 R-GGA-174587 https://reactome.org/PathwayBrowser/#/R-GGA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Gallus gallus 16113 R-GGA-176609 https://reactome.org/PathwayBrowser/#/R-GGA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Gallus gallus 16113 R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 16113 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 16113 R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 16113 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 16113 R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 16113 R-GGA-196086 https://reactome.org/PathwayBrowser/#/R-GGA-196086 Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane IEA Gallus gallus 16113 R-GGA-196126 https://reactome.org/PathwayBrowser/#/R-GGA-196126 CHOL translocates from cytosol to mitochondrial intermembrane space IEA Gallus gallus 16113 R-GGA-196417 https://reactome.org/PathwayBrowser/#/R-GGA-196417 Reduction of desmosterol to cholesterol IEA Gallus gallus 16113 R-GGA-216723 https://reactome.org/PathwayBrowser/#/R-GGA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Gallus gallus 16113 R-GGA-216756 https://reactome.org/PathwayBrowser/#/R-GGA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Gallus gallus 16113 R-GGA-2187332 https://reactome.org/PathwayBrowser/#/R-GGA-2187332 Cytosolic CMs translocate to extracellular region IEA Gallus gallus 16113 R-GGA-2197646 https://reactome.org/PathwayBrowser/#/R-GGA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Gallus gallus 16113 R-GGA-2197770 https://reactome.org/PathwayBrowser/#/R-GGA-2197770 STAB1 (FEEL-1) binds ligands IEA Gallus gallus 16113 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 16113 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 16113 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 16113 R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus 16113 R-GGA-2395764 https://reactome.org/PathwayBrowser/#/R-GGA-2395764 atREs binds to nascent CM IEA Gallus gallus 16113 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 16113 R-GGA-2512800 https://reactome.org/PathwayBrowser/#/R-GGA-2512800 SCARB1:ligand is endocytosed IEA Gallus gallus 16113 R-GGA-264678 https://reactome.org/PathwayBrowser/#/R-GGA-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Gallus gallus 16113 R-GGA-264689 https://reactome.org/PathwayBrowser/#/R-GGA-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Gallus gallus 16113 R-GGA-264695 https://reactome.org/PathwayBrowser/#/R-GGA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Gallus gallus 16113 R-GGA-265783 https://reactome.org/PathwayBrowser/#/R-GGA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Gallus gallus 16113 R-GGA-266082 https://reactome.org/PathwayBrowser/#/R-GGA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Gallus gallus 16113 R-GGA-266089 https://reactome.org/PathwayBrowser/#/R-GGA-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Gallus gallus 16113 R-GGA-266299 https://reactome.org/PathwayBrowser/#/R-GGA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Gallus gallus 16113 R-GGA-266310 https://reactome.org/PathwayBrowser/#/R-GGA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Gallus gallus 16113 R-GGA-266315 https://reactome.org/PathwayBrowser/#/R-GGA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Gallus gallus 16113 R-GGA-266328 https://reactome.org/PathwayBrowser/#/R-GGA-266328 CETP-mediated lipid exchange: spherical HDL gains triacylglycerol IEA Gallus gallus 16113 R-GGA-266350 https://reactome.org/PathwayBrowser/#/R-GGA-266350 CETP-mediated lipid exchange: LDL gains cholesterol ester IEA Gallus gallus 16113 R-GGA-349404 https://reactome.org/PathwayBrowser/#/R-GGA-349404 CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex IEA Gallus gallus 16113 R-GGA-349637 https://reactome.org/PathwayBrowser/#/R-GGA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Gallus gallus 16113 R-GGA-349638 https://reactome.org/PathwayBrowser/#/R-GGA-349638 Disassembly of SR-BI-bound spherical HDL IEA Gallus gallus 16113 R-GGA-349657 https://reactome.org/PathwayBrowser/#/R-GGA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Gallus gallus 16113 R-GGA-432121 https://reactome.org/PathwayBrowser/#/R-GGA-432121 LDL binds to LRP8 IEA Gallus gallus 16113 R-GGA-432129 https://reactome.org/PathwayBrowser/#/R-GGA-432129 FGR binds and phosphorylates LRP8 IEA Gallus gallus 16113 R-GGA-435244 https://reactome.org/PathwayBrowser/#/R-GGA-435244 PECAM1 is phosphorylated IEA Gallus gallus 16113 R-GGA-5250531 https://reactome.org/PathwayBrowser/#/R-GGA-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Gallus gallus 16113 R-GGA-5358340 https://reactome.org/PathwayBrowser/#/R-GGA-5358340 Autoproteolytic cleavage of Hh precursors IEA Gallus gallus 16113 R-GGA-6807055 https://reactome.org/PathwayBrowser/#/R-GGA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Gallus gallus 16113 R-GGA-6813720 https://reactome.org/PathwayBrowser/#/R-GGA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Gallus gallus 16113 R-GGA-8848053 https://reactome.org/PathwayBrowser/#/R-GGA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Gallus gallus 16113 R-GGA-8858252 https://reactome.org/PathwayBrowser/#/R-GGA-8858252 HDLBP binds HDL IEA Gallus gallus 16113 R-GGA-8865667 https://reactome.org/PathwayBrowser/#/R-GGA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Gallus gallus 16113 R-GGA-8866304 https://reactome.org/PathwayBrowser/#/R-GGA-8866304 pre-VLDL binds lipids to form VLDL IEA Gallus gallus 16113 R-GGA-8866327 https://reactome.org/PathwayBrowser/#/R-GGA-8866327 VLDL translocates from SER lumen to extracellular region IEA Gallus gallus 16113 R-GGA-8869667 https://reactome.org/PathwayBrowser/#/R-GGA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Gallus gallus 16113 R-GGA-8876366 https://reactome.org/PathwayBrowser/#/R-GGA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Gallus gallus 16113 R-GGA-8876472 https://reactome.org/PathwayBrowser/#/R-GGA-8876472 NPC2 binds CHOL IEA Gallus gallus 16113 R-GGA-8876484 https://reactome.org/PathwayBrowser/#/R-GGA-8876484 NPC2 transfers CHOL to NPC1 IEA Gallus gallus 16113 R-GGA-8876485 https://reactome.org/PathwayBrowser/#/R-GGA-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Gallus gallus 16113 R-GGA-8876696 https://reactome.org/PathwayBrowser/#/R-GGA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Gallus gallus 16113 R-GGA-8937442 https://reactome.org/PathwayBrowser/#/R-GGA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Gallus gallus 16113 R-GGA-8948034 https://reactome.org/PathwayBrowser/#/R-GGA-8948034 FGR binds LDL:LRP8 IEA Gallus gallus 16113 R-GGA-8951850 https://reactome.org/PathwayBrowser/#/R-GGA-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Gallus gallus 16113 R-GGA-9707586 https://reactome.org/PathwayBrowser/#/R-GGA-9707586 FeHM oxidises LDL,HDL IEA Gallus gallus 16113 R-HSA-1369028 https://reactome.org/PathwayBrowser/#/R-HSA-1369028 ABCAs mediate lipid efflux TAS Homo sapiens 16113 R-HSA-1369052 https://reactome.org/PathwayBrowser/#/R-HSA-1369052 ABCAs mediate lipid influx TAS Homo sapiens 16113 R-HSA-1454928 https://reactome.org/PathwayBrowser/#/R-HSA-1454928 ABCG4 may mediate cholesterol efflux TAS Homo sapiens 16113 R-HSA-163432 https://reactome.org/PathwayBrowser/#/R-HSA-163432 cholesterol ester + H2O -> cholesterol + fatty acid IEA Homo sapiens 16113 R-HSA-171059 https://reactome.org/PathwayBrowser/#/R-HSA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] TAS Homo sapiens 16113 R-HSA-171106 https://reactome.org/PathwayBrowser/#/R-HSA-171106 LDLR:LDL complex => LDLR + LDL TAS Homo sapiens 16113 R-HSA-171122 https://reactome.org/PathwayBrowser/#/R-HSA-171122 LDL + LDLR => LDL:LDLR complex TAS Homo sapiens 16113 R-HSA-171141 https://reactome.org/PathwayBrowser/#/R-HSA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) TAS Homo sapiens 16113 R-HSA-174587 https://reactome.org/PathwayBrowser/#/R-HSA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] TAS Homo sapiens 16113 R-HSA-174624 https://reactome.org/PathwayBrowser/#/R-HSA-174624 chylomicron remnant:apoE:LDLR complex => chylomicron remnant:apoE + LDLR IEA Homo sapiens 16113 R-HSA-174657 https://reactome.org/PathwayBrowser/#/R-HSA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex TAS Homo sapiens 16113 R-HSA-174660 https://reactome.org/PathwayBrowser/#/R-HSA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron TAS Homo sapiens 16113 R-HSA-174690 https://reactome.org/PathwayBrowser/#/R-HSA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III TAS Homo sapiens 16113 R-HSA-174706 https://reactome.org/PathwayBrowser/#/R-HSA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) TAS Homo sapiens 16113 R-HSA-174739 https://reactome.org/PathwayBrowser/#/R-HSA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex TAS Homo sapiens 16113 R-HSA-174741 https://reactome.org/PathwayBrowser/#/R-HSA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron TAS Homo sapiens 16113 R-HSA-174757 https://reactome.org/PathwayBrowser/#/R-HSA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols TAS Homo sapiens 16113 R-HSA-174808 https://reactome.org/PathwayBrowser/#/R-HSA-174808 chylomicron remnant:apoE:LDLR complex [coated vesicle membrane] => chylomicron remnant:apoE:LDLR complex [endosome membrane] IEA Homo sapiens 16113 R-HSA-176609 https://reactome.org/PathwayBrowser/#/R-HSA-176609 cholesterol + PAPS => cholesterol sulfate + PAP TAS Homo sapiens 16113 R-HSA-176879 https://reactome.org/PathwayBrowser/#/R-HSA-176879 apolipoprotein(a) + LDL => Lp(a) TAS Homo sapiens 16113 R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 16113 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 16113 R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 16113 R-HSA-192123 https://reactome.org/PathwayBrowser/#/R-HSA-192123 CYP27A1 27-hydroxylates CHOL TAS Homo sapiens 16113 R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 16113 R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 16113 R-HSA-196086 https://reactome.org/PathwayBrowser/#/R-HSA-196086 Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane TAS Homo sapiens 16113 R-HSA-196126 https://reactome.org/PathwayBrowser/#/R-HSA-196126 CHOL translocates from cytosol to mitochondrial intermembrane space TAS Homo sapiens 16113 R-HSA-196417 https://reactome.org/PathwayBrowser/#/R-HSA-196417 Reduction of desmosterol to cholesterol TAS Homo sapiens 16113 R-HSA-203130 https://reactome.org/PathwayBrowser/#/R-HSA-203130 OLR1 binds to oxidized LDL TAS Homo sapiens 16113 R-HSA-216723 https://reactome.org/PathwayBrowser/#/R-HSA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 16113 R-HSA-216756 https://reactome.org/PathwayBrowser/#/R-HSA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle TAS Homo sapiens 16113 R-HSA-2168889 https://reactome.org/PathwayBrowser/#/R-HSA-2168889 Haptoglobin-related Protein binds Hemoglobin TAS Homo sapiens 16113 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 16113 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 16113 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 16113 R-HSA-2187332 https://reactome.org/PathwayBrowser/#/R-HSA-2187332 Cytosolic CMs translocate to extracellular region TAS Homo sapiens 16113 R-HSA-2197645 https://reactome.org/PathwayBrowser/#/R-HSA-2197645 SCARF1 (SREC-I) binds ligands IEA Homo sapiens 16113 R-HSA-2197646 https://reactome.org/PathwayBrowser/#/R-HSA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands TAS Homo sapiens 16113 R-HSA-2197770 https://reactome.org/PathwayBrowser/#/R-HSA-2197770 STAB1 (FEEL-1) binds ligands TAS Homo sapiens 16113 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 16113 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 16113 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 16113 R-HSA-2247513 https://reactome.org/PathwayBrowser/#/R-HSA-2247513 STAB1:ligand is endocytosed TAS Homo sapiens 16113 R-HSA-2247514 https://reactome.org/PathwayBrowser/#/R-HSA-2247514 SCARF1:ligand is endocytosed TAS Homo sapiens 16113 R-HSA-2317530 https://reactome.org/PathwayBrowser/#/R-HSA-2317530 SREBP1A,1C,2 binds SCAP:cholesterol:INSIG and is retained in the endoplasmic reticulum IEA Homo sapiens 16113 R-HSA-2395764 https://reactome.org/PathwayBrowser/#/R-HSA-2395764 atREs binds to nascent CM TAS Homo sapiens 16113 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 16113 R-HSA-2395784 https://reactome.org/PathwayBrowser/#/R-HSA-2395784 Nascent CMs transform into mature CMs TAS Homo sapiens 16113 R-HSA-2404131 https://reactome.org/PathwayBrowser/#/R-HSA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol TAS Homo sapiens 16113 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 16113 R-HSA-2423785 https://reactome.org/PathwayBrowser/#/R-HSA-2423785 CR:atREs binds apoE and HSPG TAS Homo sapiens 16113 R-HSA-2424254 https://reactome.org/PathwayBrowser/#/R-HSA-2424254 LDLR transports extracellular CR:atREs to cytosol IEA Homo sapiens 16113 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 16113 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 16113 R-HSA-2512800 https://reactome.org/PathwayBrowser/#/R-HSA-2512800 SCARB1:ligand is endocytosed TAS Homo sapiens 16113 R-HSA-264678 https://reactome.org/PathwayBrowser/#/R-HSA-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex TAS Homo sapiens 16113 R-HSA-264689 https://reactome.org/PathwayBrowser/#/R-HSA-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL TAS Homo sapiens 16113 R-HSA-264695 https://reactome.org/PathwayBrowser/#/R-HSA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) TAS Homo sapiens 16113 R-HSA-265443 https://reactome.org/PathwayBrowser/#/R-HSA-265443 NPC1L1-mediated cholesterol uptake IEA Homo sapiens 16113 R-HSA-265783 https://reactome.org/PathwayBrowser/#/R-HSA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region TAS Homo sapiens 16113 R-HSA-266082 https://reactome.org/PathwayBrowser/#/R-HSA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface TAS Homo sapiens 16113 R-HSA-266089 https://reactome.org/PathwayBrowser/#/R-HSA-266089 Discoidal HDL binds membrane-associated free cholesterol TAS Homo sapiens 16113 R-HSA-266299 https://reactome.org/PathwayBrowser/#/R-HSA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids TAS Homo sapiens 16113 R-HSA-266303 https://reactome.org/PathwayBrowser/#/R-HSA-266303 Spherical HDL binds C and E apolipoproteins TAS Homo sapiens 16113 R-HSA-266310 https://reactome.org/PathwayBrowser/#/R-HSA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL TAS Homo sapiens 16113 R-HSA-266315 https://reactome.org/PathwayBrowser/#/R-HSA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex TAS Homo sapiens 16113 R-HSA-266328 https://reactome.org/PathwayBrowser/#/R-HSA-266328 CETP-mediated lipid exchange: spherical HDL gains triacylglycerol TAS Homo sapiens 16113 R-HSA-266350 https://reactome.org/PathwayBrowser/#/R-HSA-266350 CETP-mediated lipid exchange: LDL gains cholesterol ester TAS Homo sapiens 16113 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 16113 R-HSA-349404 https://reactome.org/PathwayBrowser/#/R-HSA-349404 CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex TAS Homo sapiens 16113 R-HSA-349637 https://reactome.org/PathwayBrowser/#/R-HSA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface TAS Homo sapiens 16113 R-HSA-349638 https://reactome.org/PathwayBrowser/#/R-HSA-349638 Disassembly of SR-BI-bound spherical HDL TAS Homo sapiens 16113 R-HSA-349657 https://reactome.org/PathwayBrowser/#/R-HSA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle TAS Homo sapiens 16113 R-HSA-432121 https://reactome.org/PathwayBrowser/#/R-HSA-432121 LDL binds to LRP8 TAS Homo sapiens 16113 R-HSA-432129 https://reactome.org/PathwayBrowser/#/R-HSA-432129 FGR binds and phosphorylates LRP8 TAS Homo sapiens 16113 R-HSA-435244 https://reactome.org/PathwayBrowser/#/R-HSA-435244 PECAM1 is phosphorylated TAS Homo sapiens 16113 R-HSA-5250531 https://reactome.org/PathwayBrowser/#/R-HSA-5250531 ARV1 transports CHOL from ER membrane to plasma membrane TAS Homo sapiens 16113 R-HSA-5358340 https://reactome.org/PathwayBrowser/#/R-HSA-5358340 Autoproteolytic cleavage of Hh precursors TAS Homo sapiens 16113 R-HSA-5358460 https://reactome.org/PathwayBrowser/#/R-HSA-5358460 HPE SHH variants don't undergo autoproteolytic cleavage TAS Homo sapiens 16113 R-HSA-5679101 https://reactome.org/PathwayBrowser/#/R-HSA-5679101 Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 16113 R-HSA-5679145 https://reactome.org/PathwayBrowser/#/R-HSA-5679145 Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 16113 R-HSA-5682111 https://reactome.org/PathwayBrowser/#/R-HSA-5682111 Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 16113 R-HSA-6807055 https://reactome.org/PathwayBrowser/#/R-HSA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL TAS Homo sapiens 16113 R-HSA-6810937 https://reactome.org/PathwayBrowser/#/R-HSA-6810937 Lamellar bodies bind the early cornified envelope TAS Homo sapiens 16113 R-HSA-6813720 https://reactome.org/PathwayBrowser/#/R-HSA-6813720 NCEH1 hydrolyzes cholesterol esters TAS Homo sapiens 16113 R-HSA-6814298 https://reactome.org/PathwayBrowser/#/R-HSA-6814298 Late envelope proteins bind cornified envelope:CDSN TAS Homo sapiens 16113 R-HSA-6814387 https://reactome.org/PathwayBrowser/#/R-HSA-6814387 CASP14 cleaves filaggrin TAS Homo sapiens 16113 R-HSA-6814734 https://reactome.org/PathwayBrowser/#/R-HSA-6814734 CDSN binds the cornified envelope TAS Homo sapiens 16113 R-HSA-6814764 https://reactome.org/PathwayBrowser/#/R-HSA-6814764 Plasma membrane resorption TAS Homo sapiens 16113 R-HSA-8848053 https://reactome.org/PathwayBrowser/#/R-HSA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol TAS Homo sapiens 16113 R-HSA-8854408 https://reactome.org/PathwayBrowser/#/R-HSA-8854408 APOBR dimer binds VLDLs TAS Homo sapiens 16113 R-HSA-8854462 https://reactome.org/PathwayBrowser/#/R-HSA-8854462 VLDLR binds VLDL TAS Homo sapiens 16113 R-HSA-8858252 https://reactome.org/PathwayBrowser/#/R-HSA-8858252 HDLBP binds HDL TAS Homo sapiens 16113 R-HSA-8863471 https://reactome.org/PathwayBrowser/#/R-HSA-8863471 LDLR is bound by DAB2 and ARH TAS Homo sapiens 16113 R-HSA-8865667 https://reactome.org/PathwayBrowser/#/R-HSA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids TAS Homo sapiens 16113 R-HSA-8866304 https://reactome.org/PathwayBrowser/#/R-HSA-8866304 pre-VLDL binds lipids to form VLDL TAS Homo sapiens 16113 R-HSA-8866321 https://reactome.org/PathwayBrowser/#/R-HSA-8866321 VLDL binds APOC1 and APOC4 TAS Homo sapiens 16113 R-HSA-8866327 https://reactome.org/PathwayBrowser/#/R-HSA-8866327 VLDL translocates from SER lumen to extracellular region TAS Homo sapiens 16113 R-HSA-8867754 https://reactome.org/PathwayBrowser/#/R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit TAS Homo sapiens 16113 R-HSA-8867756 https://reactome.org/PathwayBrowser/#/R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit TAS Homo sapiens 16113 R-HSA-8868071 https://reactome.org/PathwayBrowser/#/R-HSA-8868071 Clathrin recruits PIK3C2A TAS Homo sapiens 16113 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 16113 R-HSA-8868230 https://reactome.org/PathwayBrowser/#/R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery TAS Homo sapiens 16113 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 16113 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 16113 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 16113 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 16113 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 16113 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 16113 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 16113 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 16113 R-HSA-8869667 https://reactome.org/PathwayBrowser/#/R-HSA-8869667 oxLDL:CD36 binds TLR4:TLR6 TAS Homo sapiens 16113 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 16113 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 16113 R-HSA-8876366 https://reactome.org/PathwayBrowser/#/R-HSA-8876366 LDL translocates from endosome lumen to lysosome lumen TAS Homo sapiens 16113 R-HSA-8876472 https://reactome.org/PathwayBrowser/#/R-HSA-8876472 NPC2 binds CHOL TAS Homo sapiens 16113 R-HSA-8876484 https://reactome.org/PathwayBrowser/#/R-HSA-8876484 NPC2 transfers CHOL to NPC1 TAS Homo sapiens 16113 R-HSA-8876485 https://reactome.org/PathwayBrowser/#/R-HSA-8876485 CHOL translocates from lysosome membrane to ER membrane TAS Homo sapiens 16113 R-HSA-8876696 https://reactome.org/PathwayBrowser/#/R-HSA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST TAS Homo sapiens 16113 R-HSA-8933258 https://reactome.org/PathwayBrowser/#/R-HSA-8933258 LSR trimer binds LDL IEA Homo sapiens 16113 R-HSA-8933292 https://reactome.org/PathwayBrowser/#/R-HSA-8933292 LSR trimer binds VLDL IEA Homo sapiens 16113 R-HSA-8937442 https://reactome.org/PathwayBrowser/#/R-HSA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) TAS Homo sapiens 16113 R-HSA-8948034 https://reactome.org/PathwayBrowser/#/R-HSA-8948034 FGR binds LDL:LRP8 TAS Homo sapiens 16113 R-HSA-8951850 https://reactome.org/PathwayBrowser/#/R-HSA-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane TAS Homo sapiens 16113 R-HSA-9707586 https://reactome.org/PathwayBrowser/#/R-HSA-9707586 FeHM oxidises LDL,HDL TAS Homo sapiens 16113 R-MMU-1369028 https://reactome.org/PathwayBrowser/#/R-MMU-1369028 ABCAs mediate lipid efflux IEA Mus musculus 16113 R-MMU-1369052 https://reactome.org/PathwayBrowser/#/R-MMU-1369052 ABCAs mediate lipid influx IEA Mus musculus 16113 R-MMU-1454928 https://reactome.org/PathwayBrowser/#/R-MMU-1454928 ABCG4 may mediate cholesterol efflux IEA Mus musculus 16113 R-MMU-171059 https://reactome.org/PathwayBrowser/#/R-MMU-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Mus musculus 16113 R-MMU-171106 https://reactome.org/PathwayBrowser/#/R-MMU-171106 LDLR:LDL complex => LDLR + LDL IEA Mus musculus 16113 R-MMU-171122 https://reactome.org/PathwayBrowser/#/R-MMU-171122 LDL + LDLR => LDL:LDLR complex IEA Mus musculus 16113 R-MMU-171141 https://reactome.org/PathwayBrowser/#/R-MMU-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Mus musculus 16113 R-MMU-174587 https://reactome.org/PathwayBrowser/#/R-MMU-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Mus musculus 16113 R-MMU-174657 https://reactome.org/PathwayBrowser/#/R-MMU-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Mus musculus 16113 R-MMU-174660 https://reactome.org/PathwayBrowser/#/R-MMU-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Mus musculus 16113 R-MMU-174690 https://reactome.org/PathwayBrowser/#/R-MMU-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Mus musculus 16113 R-MMU-174706 https://reactome.org/PathwayBrowser/#/R-MMU-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Mus musculus 16113 R-MMU-174739 https://reactome.org/PathwayBrowser/#/R-MMU-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Mus musculus 16113 R-MMU-174741 https://reactome.org/PathwayBrowser/#/R-MMU-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Mus musculus 16113 R-MMU-174757 https://reactome.org/PathwayBrowser/#/R-MMU-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Mus musculus 16113 R-MMU-176609 https://reactome.org/PathwayBrowser/#/R-MMU-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Mus musculus 16113 R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 16113 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 16113 R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 16113 R-MMU-192123 https://reactome.org/PathwayBrowser/#/R-MMU-192123 CYP27A1 27-hydroxylates CHOL IEA Mus musculus 16113 R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 16113 R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 16113 R-MMU-196086 https://reactome.org/PathwayBrowser/#/R-MMU-196086 Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane IEA Mus musculus 16113 R-MMU-196126 https://reactome.org/PathwayBrowser/#/R-MMU-196126 CHOL translocates from cytosol to mitochondrial intermembrane space IEA Mus musculus 16113 R-MMU-196417 https://reactome.org/PathwayBrowser/#/R-MMU-196417 Reduction of desmosterol to cholesterol IEA Mus musculus 16113 R-MMU-203130 https://reactome.org/PathwayBrowser/#/R-MMU-203130 OLR1 binds to oxidized LDL IEA Mus musculus 16113 R-MMU-216723 https://reactome.org/PathwayBrowser/#/R-MMU-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Mus musculus 16113 R-MMU-216756 https://reactome.org/PathwayBrowser/#/R-MMU-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Mus musculus 16113 R-MMU-2168889 https://reactome.org/PathwayBrowser/#/R-MMU-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Mus musculus 16113 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 16113 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 16113 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 16113 R-MMU-2187332 https://reactome.org/PathwayBrowser/#/R-MMU-2187332 Cytosolic CMs translocate to extracellular region IEA Mus musculus 16113 R-MMU-2197646 https://reactome.org/PathwayBrowser/#/R-MMU-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Mus musculus 16113 R-MMU-2197770 https://reactome.org/PathwayBrowser/#/R-MMU-2197770 STAB1 (FEEL-1) binds ligands IEA Mus musculus 16113 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 16113 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 16113 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 16113 R-MMU-2247513 https://reactome.org/PathwayBrowser/#/R-MMU-2247513 STAB1:ligand is endocytosed IEA Mus musculus 16113 R-MMU-2395764 https://reactome.org/PathwayBrowser/#/R-MMU-2395764 atREs binds to nascent CM IEA Mus musculus 16113 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 16113 R-MMU-2395784 https://reactome.org/PathwayBrowser/#/R-MMU-2395784 Nascent CMs transform into mature CMs IEA Mus musculus 16113 R-MMU-2404131 https://reactome.org/PathwayBrowser/#/R-MMU-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Mus musculus 16113 R-MMU-2423785 https://reactome.org/PathwayBrowser/#/R-MMU-2423785 CR:atREs binds apoE and HSPG IEA Mus musculus 16113 R-MMU-2425403 https://reactome.org/PathwayBrowser/#/R-MMU-2425403 Extracellular CR:atREs are transported to cytosol by Ldlr TAS Mus musculus 16113 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 16113 R-MMU-2512800 https://reactome.org/PathwayBrowser/#/R-MMU-2512800 SCARB1:ligand is endocytosed IEA Mus musculus 16113 R-MMU-264678 https://reactome.org/PathwayBrowser/#/R-MMU-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Mus musculus 16113 R-MMU-264689 https://reactome.org/PathwayBrowser/#/R-MMU-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Mus musculus 16113 R-MMU-264695 https://reactome.org/PathwayBrowser/#/R-MMU-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Mus musculus 16113 R-MMU-265783 https://reactome.org/PathwayBrowser/#/R-MMU-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Mus musculus 16113 R-MMU-266082 https://reactome.org/PathwayBrowser/#/R-MMU-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Mus musculus 16113 R-MMU-266089 https://reactome.org/PathwayBrowser/#/R-MMU-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Mus musculus 16113 R-MMU-266299 https://reactome.org/PathwayBrowser/#/R-MMU-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Mus musculus 16113 R-MMU-266303 https://reactome.org/PathwayBrowser/#/R-MMU-266303 Spherical HDL binds C and E apolipoproteins IEA Mus musculus 16113 R-MMU-266310 https://reactome.org/PathwayBrowser/#/R-MMU-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Mus musculus 16113 R-MMU-266315 https://reactome.org/PathwayBrowser/#/R-MMU-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Mus musculus 16113 R-MMU-349637 https://reactome.org/PathwayBrowser/#/R-MMU-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Mus musculus 16113 R-MMU-349638 https://reactome.org/PathwayBrowser/#/R-MMU-349638 Disassembly of SR-BI-bound spherical HDL IEA Mus musculus 16113 R-MMU-349657 https://reactome.org/PathwayBrowser/#/R-MMU-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Mus musculus 16113 R-MMU-432121 https://reactome.org/PathwayBrowser/#/R-MMU-432121 LDL binds to LRP8 IEA Mus musculus 16113 R-MMU-432129 https://reactome.org/PathwayBrowser/#/R-MMU-432129 FGR binds and phosphorylates LRP8 IEA Mus musculus 16113 R-MMU-435244 https://reactome.org/PathwayBrowser/#/R-MMU-435244 PECAM1 is phosphorylated IEA Mus musculus 16113 R-MMU-5250531 https://reactome.org/PathwayBrowser/#/R-MMU-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Mus musculus 16113 R-MMU-5358340 https://reactome.org/PathwayBrowser/#/R-MMU-5358340 Autoproteolytic cleavage of Hh precursors IEA Mus musculus 16113 R-MMU-6807055 https://reactome.org/PathwayBrowser/#/R-MMU-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Mus musculus 16113 R-MMU-6810937 https://reactome.org/PathwayBrowser/#/R-MMU-6810937 Lamellar bodies bind the early cornified envelope IEA Mus musculus 16113 R-MMU-6813720 https://reactome.org/PathwayBrowser/#/R-MMU-6813720 NCEH1 hydrolyzes cholesterol esters IEA Mus musculus 16113 R-MMU-6814387 https://reactome.org/PathwayBrowser/#/R-MMU-6814387 CASP14 cleaves filaggrin IEA Mus musculus 16113 R-MMU-6814734 https://reactome.org/PathwayBrowser/#/R-MMU-6814734 CDSN binds the cornified envelope IEA Mus musculus 16113 R-MMU-6814764 https://reactome.org/PathwayBrowser/#/R-MMU-6814764 Plasma membrane resorption IEA Mus musculus 16113 R-MMU-8848053 https://reactome.org/PathwayBrowser/#/R-MMU-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Mus musculus 16113 R-MMU-8854408 https://reactome.org/PathwayBrowser/#/R-MMU-8854408 APOBR dimer binds VLDLs IEA Mus musculus 16113 R-MMU-8854462 https://reactome.org/PathwayBrowser/#/R-MMU-8854462 VLDLR binds VLDL IEA Mus musculus 16113 R-MMU-8858252 https://reactome.org/PathwayBrowser/#/R-MMU-8858252 HDLBP binds HDL IEA Mus musculus 16113 R-MMU-8863471 https://reactome.org/PathwayBrowser/#/R-MMU-8863471 LDLR is bound by DAB2 and ARH IEA Mus musculus 16113 R-MMU-8865667 https://reactome.org/PathwayBrowser/#/R-MMU-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Mus musculus 16113 R-MMU-8866304 https://reactome.org/PathwayBrowser/#/R-MMU-8866304 pre-VLDL binds lipids to form VLDL IEA Mus musculus 16113 R-MMU-8866321 https://reactome.org/PathwayBrowser/#/R-MMU-8866321 VLDL binds APOC1 and APOC4 IEA Mus musculus 16113 R-MMU-8866327 https://reactome.org/PathwayBrowser/#/R-MMU-8866327 VLDL translocates from SER lumen to extracellular region IEA Mus musculus 16113 R-MMU-8867754 https://reactome.org/PathwayBrowser/#/R-MMU-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Mus musculus 16113 R-MMU-8867756 https://reactome.org/PathwayBrowser/#/R-MMU-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Mus musculus 16113 R-MMU-8868071 https://reactome.org/PathwayBrowser/#/R-MMU-8868071 Clathrin recruits PIK3C2A IEA Mus musculus 16113 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 16113 R-MMU-8868236 https://reactome.org/PathwayBrowser/#/R-MMU-8868236 BAR domain proteins recruit dynamin IEA Mus musculus 16113 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 16113 R-MMU-8868651 https://reactome.org/PathwayBrowser/#/R-MMU-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Mus musculus 16113 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 16113 R-MMU-8868659 https://reactome.org/PathwayBrowser/#/R-MMU-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Mus musculus 16113 R-MMU-8868660 https://reactome.org/PathwayBrowser/#/R-MMU-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Mus musculus 16113 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 16113 R-MMU-8869667 https://reactome.org/PathwayBrowser/#/R-MMU-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Mus musculus 16113 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 16113 R-MMU-8871194 https://reactome.org/PathwayBrowser/#/R-MMU-8871194 RAB5 and GAPVD1 bind AP-2 IEA Mus musculus 16113 R-MMU-8876366 https://reactome.org/PathwayBrowser/#/R-MMU-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Mus musculus 16113 R-MMU-8876472 https://reactome.org/PathwayBrowser/#/R-MMU-8876472 NPC2 binds CHOL IEA Mus musculus 16113 R-MMU-8876484 https://reactome.org/PathwayBrowser/#/R-MMU-8876484 NPC2 transfers CHOL to NPC1 IEA Mus musculus 16113 R-MMU-8876485 https://reactome.org/PathwayBrowser/#/R-MMU-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Mus musculus 16113 R-MMU-8876696 https://reactome.org/PathwayBrowser/#/R-MMU-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Mus musculus 16113 R-MMU-8933256 https://reactome.org/PathwayBrowser/#/R-MMU-8933256 Lsr trimer binds LDL TAS Mus musculus 16113 R-MMU-8933295 https://reactome.org/PathwayBrowser/#/R-MMU-8933295 Lsr trimer binds VLDL TAS Mus musculus 16113 R-MMU-8937442 https://reactome.org/PathwayBrowser/#/R-MMU-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Mus musculus 16113 R-MMU-8948034 https://reactome.org/PathwayBrowser/#/R-MMU-8948034 FGR binds LDL:LRP8 IEA Mus musculus 16113 R-MMU-8951850 https://reactome.org/PathwayBrowser/#/R-MMU-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Mus musculus 16113 R-MMU-9707586 https://reactome.org/PathwayBrowser/#/R-MMU-9707586 FeHM oxidises LDL,HDL IEA Mus musculus 16113 R-NUL-2317526 https://reactome.org/PathwayBrowser/#/R-NUL-2317526 SREBP1A/1C/2 is retained in the endoplasmic reticulum by SCAP:cholesterol:INSIG TAS Cricetulus griseus 16113 R-PFA-1369028 https://reactome.org/PathwayBrowser/#/R-PFA-1369028 ABCAs mediate lipid efflux IEA Plasmodium falciparum 16113 R-PFA-1369052 https://reactome.org/PathwayBrowser/#/R-PFA-1369052 ABCAs mediate lipid influx IEA Plasmodium falciparum 16113 R-PFA-265783 https://reactome.org/PathwayBrowser/#/R-PFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Plasmodium falciparum 16113 R-PFA-5250531 https://reactome.org/PathwayBrowser/#/R-PFA-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Plasmodium falciparum 16113 R-PFA-8848053 https://reactome.org/PathwayBrowser/#/R-PFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Plasmodium falciparum 16113 R-RNO-1369028 https://reactome.org/PathwayBrowser/#/R-RNO-1369028 ABCAs mediate lipid efflux IEA Rattus norvegicus 16113 R-RNO-1369052 https://reactome.org/PathwayBrowser/#/R-RNO-1369052 ABCAs mediate lipid influx IEA Rattus norvegicus 16113 R-RNO-1454928 https://reactome.org/PathwayBrowser/#/R-RNO-1454928 ABCG4 may mediate cholesterol efflux IEA Rattus norvegicus 16113 R-RNO-163407 https://reactome.org/PathwayBrowser/#/R-RNO-163407 cholesterol ester + H2O -> cholesterol + fatty acid TAS Rattus norvegicus 16113 R-RNO-171059 https://reactome.org/PathwayBrowser/#/R-RNO-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Rattus norvegicus 16113 R-RNO-171106 https://reactome.org/PathwayBrowser/#/R-RNO-171106 LDLR:LDL complex => LDLR + LDL IEA Rattus norvegicus 16113 R-RNO-171122 https://reactome.org/PathwayBrowser/#/R-RNO-171122 LDL + LDLR => LDL:LDLR complex IEA Rattus norvegicus 16113 R-RNO-171141 https://reactome.org/PathwayBrowser/#/R-RNO-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Rattus norvegicus 16113 R-RNO-174587 https://reactome.org/PathwayBrowser/#/R-RNO-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Rattus norvegicus 16113 R-RNO-174657 https://reactome.org/PathwayBrowser/#/R-RNO-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Rattus norvegicus 16113 R-RNO-174660 https://reactome.org/PathwayBrowser/#/R-RNO-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Rattus norvegicus 16113 R-RNO-174690 https://reactome.org/PathwayBrowser/#/R-RNO-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Rattus norvegicus 16113 R-RNO-174706 https://reactome.org/PathwayBrowser/#/R-RNO-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Rattus norvegicus 16113 R-RNO-174739 https://reactome.org/PathwayBrowser/#/R-RNO-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Rattus norvegicus 16113 R-RNO-174741 https://reactome.org/PathwayBrowser/#/R-RNO-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Rattus norvegicus 16113 R-RNO-174757 https://reactome.org/PathwayBrowser/#/R-RNO-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Rattus norvegicus 16113 R-RNO-176609 https://reactome.org/PathwayBrowser/#/R-RNO-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Rattus norvegicus 16113 R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 16113 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 16113 R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 16113 R-RNO-192123 https://reactome.org/PathwayBrowser/#/R-RNO-192123 CYP27A1 27-hydroxylates CHOL IEA Rattus norvegicus 16113 R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 16113 R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 16113 R-RNO-196086 https://reactome.org/PathwayBrowser/#/R-RNO-196086 Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane IEA Rattus norvegicus 16113 R-RNO-196126 https://reactome.org/PathwayBrowser/#/R-RNO-196126 CHOL translocates from cytosol to mitochondrial intermembrane space IEA Rattus norvegicus 16113 R-RNO-196417 https://reactome.org/PathwayBrowser/#/R-RNO-196417 Reduction of desmosterol to cholesterol IEA Rattus norvegicus 16113 R-RNO-203130 https://reactome.org/PathwayBrowser/#/R-RNO-203130 OLR1 binds to oxidized LDL IEA Rattus norvegicus 16113 R-RNO-216723 https://reactome.org/PathwayBrowser/#/R-RNO-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 16113 R-RNO-216756 https://reactome.org/PathwayBrowser/#/R-RNO-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Rattus norvegicus 16113 R-RNO-2168889 https://reactome.org/PathwayBrowser/#/R-RNO-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Rattus norvegicus 16113 R-RNO-2187332 https://reactome.org/PathwayBrowser/#/R-RNO-2187332 Cytosolic CMs translocate to extracellular region IEA Rattus norvegicus 16113 R-RNO-2197646 https://reactome.org/PathwayBrowser/#/R-RNO-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Rattus norvegicus 16113 R-RNO-2197770 https://reactome.org/PathwayBrowser/#/R-RNO-2197770 STAB1 (FEEL-1) binds ligands IEA Rattus norvegicus 16113 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 16113 R-RNO-2247513 https://reactome.org/PathwayBrowser/#/R-RNO-2247513 STAB1:ligand is endocytosed IEA Rattus norvegicus 16113 R-RNO-2395764 https://reactome.org/PathwayBrowser/#/R-RNO-2395764 atREs binds to nascent CM IEA Rattus norvegicus 16113 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 16113 R-RNO-2395784 https://reactome.org/PathwayBrowser/#/R-RNO-2395784 Nascent CMs transform into mature CMs IEA Rattus norvegicus 16113 R-RNO-2404131 https://reactome.org/PathwayBrowser/#/R-RNO-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Rattus norvegicus 16113 R-RNO-2423785 https://reactome.org/PathwayBrowser/#/R-RNO-2423785 CR:atREs binds apoE and HSPG IEA Rattus norvegicus 16113 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 16113 R-RNO-2512800 https://reactome.org/PathwayBrowser/#/R-RNO-2512800 SCARB1:ligand is endocytosed IEA Rattus norvegicus 16113 R-RNO-264678 https://reactome.org/PathwayBrowser/#/R-RNO-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Rattus norvegicus 16113 R-RNO-264689 https://reactome.org/PathwayBrowser/#/R-RNO-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Rattus norvegicus 16113 R-RNO-264695 https://reactome.org/PathwayBrowser/#/R-RNO-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Rattus norvegicus 16113 R-RNO-265783 https://reactome.org/PathwayBrowser/#/R-RNO-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Rattus norvegicus 16113 R-RNO-266082 https://reactome.org/PathwayBrowser/#/R-RNO-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Rattus norvegicus 16113 R-RNO-266089 https://reactome.org/PathwayBrowser/#/R-RNO-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Rattus norvegicus 16113 R-RNO-266299 https://reactome.org/PathwayBrowser/#/R-RNO-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Rattus norvegicus 16113 R-RNO-266303 https://reactome.org/PathwayBrowser/#/R-RNO-266303 Spherical HDL binds C and E apolipoproteins IEA Rattus norvegicus 16113 R-RNO-266310 https://reactome.org/PathwayBrowser/#/R-RNO-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Rattus norvegicus 16113 R-RNO-266315 https://reactome.org/PathwayBrowser/#/R-RNO-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Rattus norvegicus 16113 R-RNO-349637 https://reactome.org/PathwayBrowser/#/R-RNO-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Rattus norvegicus 16113 R-RNO-349638 https://reactome.org/PathwayBrowser/#/R-RNO-349638 Disassembly of SR-BI-bound spherical HDL IEA Rattus norvegicus 16113 R-RNO-349657 https://reactome.org/PathwayBrowser/#/R-RNO-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Rattus norvegicus 16113 R-RNO-432121 https://reactome.org/PathwayBrowser/#/R-RNO-432121 LDL binds to LRP8 IEA Rattus norvegicus 16113 R-RNO-432129 https://reactome.org/PathwayBrowser/#/R-RNO-432129 FGR binds and phosphorylates LRP8 IEA Rattus norvegicus 16113 R-RNO-435244 https://reactome.org/PathwayBrowser/#/R-RNO-435244 PECAM1 is phosphorylated IEA Rattus norvegicus 16113 R-RNO-5250531 https://reactome.org/PathwayBrowser/#/R-RNO-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Rattus norvegicus 16113 R-RNO-5358340 https://reactome.org/PathwayBrowser/#/R-RNO-5358340 Autoproteolytic cleavage of Hh precursors IEA Rattus norvegicus 16113 R-RNO-6807055 https://reactome.org/PathwayBrowser/#/R-RNO-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Rattus norvegicus 16113 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus 16113 R-RNO-6813720 https://reactome.org/PathwayBrowser/#/R-RNO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Rattus norvegicus 16113 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus 16113 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus 16113 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus 16113 R-RNO-8848053 https://reactome.org/PathwayBrowser/#/R-RNO-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Rattus norvegicus 16113 R-RNO-8854408 https://reactome.org/PathwayBrowser/#/R-RNO-8854408 APOBR dimer binds VLDLs IEA Rattus norvegicus 16113 R-RNO-8854462 https://reactome.org/PathwayBrowser/#/R-RNO-8854462 VLDLR binds VLDL IEA Rattus norvegicus 16113 R-RNO-8858252 https://reactome.org/PathwayBrowser/#/R-RNO-8858252 HDLBP binds HDL IEA Rattus norvegicus 16113 R-RNO-8863471 https://reactome.org/PathwayBrowser/#/R-RNO-8863471 LDLR is bound by DAB2 and ARH IEA Rattus norvegicus 16113 R-RNO-8865667 https://reactome.org/PathwayBrowser/#/R-RNO-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Rattus norvegicus 16113 R-RNO-8866304 https://reactome.org/PathwayBrowser/#/R-RNO-8866304 pre-VLDL binds lipids to form VLDL IEA Rattus norvegicus 16113 R-RNO-8866321 https://reactome.org/PathwayBrowser/#/R-RNO-8866321 VLDL binds APOC1 and APOC4 IEA Rattus norvegicus 16113 R-RNO-8866327 https://reactome.org/PathwayBrowser/#/R-RNO-8866327 VLDL translocates from SER lumen to extracellular region IEA Rattus norvegicus 16113 R-RNO-8867754 https://reactome.org/PathwayBrowser/#/R-RNO-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Rattus norvegicus 16113 R-RNO-8867756 https://reactome.org/PathwayBrowser/#/R-RNO-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Rattus norvegicus 16113 R-RNO-8868071 https://reactome.org/PathwayBrowser/#/R-RNO-8868071 Clathrin recruits PIK3C2A IEA Rattus norvegicus 16113 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 16113 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus 16113 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 16113 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus 16113 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 16113 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus 16113 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus 16113 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 16113 R-RNO-8869667 https://reactome.org/PathwayBrowser/#/R-RNO-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Rattus norvegicus 16113 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 16113 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus 16113 R-RNO-8876366 https://reactome.org/PathwayBrowser/#/R-RNO-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Rattus norvegicus 16113 R-RNO-8876472 https://reactome.org/PathwayBrowser/#/R-RNO-8876472 NPC2 binds CHOL IEA Rattus norvegicus 16113 R-RNO-8876484 https://reactome.org/PathwayBrowser/#/R-RNO-8876484 NPC2 transfers CHOL to NPC1 IEA Rattus norvegicus 16113 R-RNO-8876485 https://reactome.org/PathwayBrowser/#/R-RNO-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Rattus norvegicus 16113 R-RNO-8876696 https://reactome.org/PathwayBrowser/#/R-RNO-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Rattus norvegicus 16113 R-RNO-8948034 https://reactome.org/PathwayBrowser/#/R-RNO-8948034 FGR binds LDL:LRP8 IEA Rattus norvegicus 16113 R-RNO-8951850 https://reactome.org/PathwayBrowser/#/R-RNO-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Rattus norvegicus 16113 R-RNO-9707586 https://reactome.org/PathwayBrowser/#/R-RNO-9707586 FeHM oxidises LDL,HDL IEA Rattus norvegicus 16113 R-SCE-1454928 https://reactome.org/PathwayBrowser/#/R-SCE-1454928 ABCG4 may mediate cholesterol efflux IEA Saccharomyces cerevisiae 16113 R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 16113 R-SCE-264695 https://reactome.org/PathwayBrowser/#/R-SCE-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Saccharomyces cerevisiae 16113 R-SCE-265783 https://reactome.org/PathwayBrowser/#/R-SCE-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Saccharomyces cerevisiae 16113 R-SCE-266082 https://reactome.org/PathwayBrowser/#/R-SCE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Saccharomyces cerevisiae 16113 R-SCE-5250531 https://reactome.org/PathwayBrowser/#/R-SCE-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Saccharomyces cerevisiae 16113 R-SCE-8876472 https://reactome.org/PathwayBrowser/#/R-SCE-8876472 NPC2 binds CHOL IEA Saccharomyces cerevisiae 16113 R-SCE-8876484 https://reactome.org/PathwayBrowser/#/R-SCE-8876484 NPC2 transfers CHOL to NPC1 IEA Saccharomyces cerevisiae 16113 R-SCE-8876485 https://reactome.org/PathwayBrowser/#/R-SCE-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Saccharomyces cerevisiae 16113 R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 16113 R-SPO-5250531 https://reactome.org/PathwayBrowser/#/R-SPO-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Schizosaccharomyces pombe 16113 R-SPO-6813720 https://reactome.org/PathwayBrowser/#/R-SPO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Schizosaccharomyces pombe 16113 R-SPO-8876472 https://reactome.org/PathwayBrowser/#/R-SPO-8876472 NPC2 binds CHOL IEA Schizosaccharomyces pombe 16113 R-SSC-1369028 https://reactome.org/PathwayBrowser/#/R-SSC-1369028 ABCAs mediate lipid efflux IEA Sus scrofa 16113 R-SSC-1369052 https://reactome.org/PathwayBrowser/#/R-SSC-1369052 ABCAs mediate lipid influx IEA Sus scrofa 16113 R-SSC-171059 https://reactome.org/PathwayBrowser/#/R-SSC-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Sus scrofa 16113 R-SSC-171106 https://reactome.org/PathwayBrowser/#/R-SSC-171106 LDLR:LDL complex => LDLR + LDL IEA Sus scrofa 16113 R-SSC-171122 https://reactome.org/PathwayBrowser/#/R-SSC-171122 LDL + LDLR => LDL:LDLR complex IEA Sus scrofa 16113 R-SSC-171141 https://reactome.org/PathwayBrowser/#/R-SSC-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Sus scrofa 16113 R-SSC-174587 https://reactome.org/PathwayBrowser/#/R-SSC-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Sus scrofa 16113 R-SSC-174657 https://reactome.org/PathwayBrowser/#/R-SSC-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Sus scrofa 16113 R-SSC-174660 https://reactome.org/PathwayBrowser/#/R-SSC-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Sus scrofa 16113 R-SSC-174690 https://reactome.org/PathwayBrowser/#/R-SSC-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Sus scrofa 16113 R-SSC-174706 https://reactome.org/PathwayBrowser/#/R-SSC-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Sus scrofa 16113 R-SSC-174739 https://reactome.org/PathwayBrowser/#/R-SSC-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Sus scrofa 16113 R-SSC-174741 https://reactome.org/PathwayBrowser/#/R-SSC-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Sus scrofa 16113 R-SSC-174757 https://reactome.org/PathwayBrowser/#/R-SSC-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Sus scrofa 16113 R-SSC-176609 https://reactome.org/PathwayBrowser/#/R-SSC-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Sus scrofa 16113 R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 16113 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 16113 R-SSC-192061 https://reactome.org/PathwayBrowser/#/R-SSC-192061 CYP46A1 24-hydroxylates CHOL IEA Sus scrofa 16113 R-SSC-192123 https://reactome.org/PathwayBrowser/#/R-SSC-192123 CYP27A1 27-hydroxylates CHOL IEA Sus scrofa 16113 R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 16113 R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 16113 R-SSC-196086 https://reactome.org/PathwayBrowser/#/R-SSC-196086 Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane IEA Sus scrofa 16113 R-SSC-196126 https://reactome.org/PathwayBrowser/#/R-SSC-196126 CHOL translocates from cytosol to mitochondrial intermembrane space IEA Sus scrofa 16113 R-SSC-196417 https://reactome.org/PathwayBrowser/#/R-SSC-196417 Reduction of desmosterol to cholesterol IEA Sus scrofa 16113 R-SSC-203130 https://reactome.org/PathwayBrowser/#/R-SSC-203130 OLR1 binds to oxidized LDL IEA Sus scrofa 16113 R-SSC-216723 https://reactome.org/PathwayBrowser/#/R-SSC-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Sus scrofa 16113 R-SSC-216756 https://reactome.org/PathwayBrowser/#/R-SSC-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Sus scrofa 16113 R-SSC-2168889 https://reactome.org/PathwayBrowser/#/R-SSC-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Sus scrofa 16113 R-SSC-2187332 https://reactome.org/PathwayBrowser/#/R-SSC-2187332 Cytosolic CMs translocate to extracellular region IEA Sus scrofa 16113 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa 16113 R-SSC-2197770 https://reactome.org/PathwayBrowser/#/R-SSC-2197770 STAB1 (FEEL-1) binds ligands IEA Sus scrofa 16113 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 16113 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 16113 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 16113 R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa 16113 R-SSC-2395764 https://reactome.org/PathwayBrowser/#/R-SSC-2395764 atREs binds to nascent CM IEA Sus scrofa 16113 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 16113 R-SSC-2395784 https://reactome.org/PathwayBrowser/#/R-SSC-2395784 Nascent CMs transform into mature CMs IEA Sus scrofa 16113 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa 16113 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa 16113 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 16113 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa 16113 R-SSC-264678 https://reactome.org/PathwayBrowser/#/R-SSC-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Sus scrofa 16113 R-SSC-264689 https://reactome.org/PathwayBrowser/#/R-SSC-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Sus scrofa 16113 R-SSC-264695 https://reactome.org/PathwayBrowser/#/R-SSC-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Sus scrofa 16113 R-SSC-265783 https://reactome.org/PathwayBrowser/#/R-SSC-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Sus scrofa 16113 R-SSC-266082 https://reactome.org/PathwayBrowser/#/R-SSC-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Sus scrofa 16113 R-SSC-266089 https://reactome.org/PathwayBrowser/#/R-SSC-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Sus scrofa 16113 R-SSC-266299 https://reactome.org/PathwayBrowser/#/R-SSC-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Sus scrofa 16113 R-SSC-266303 https://reactome.org/PathwayBrowser/#/R-SSC-266303 Spherical HDL binds C and E apolipoproteins IEA Sus scrofa 16113 R-SSC-266310 https://reactome.org/PathwayBrowser/#/R-SSC-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Sus scrofa 16113 R-SSC-266315 https://reactome.org/PathwayBrowser/#/R-SSC-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Sus scrofa 16113 R-SSC-349637 https://reactome.org/PathwayBrowser/#/R-SSC-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Sus scrofa 16113 R-SSC-349638 https://reactome.org/PathwayBrowser/#/R-SSC-349638 Disassembly of SR-BI-bound spherical HDL IEA Sus scrofa 16113 R-SSC-349657 https://reactome.org/PathwayBrowser/#/R-SSC-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Sus scrofa 16113 R-SSC-432121 https://reactome.org/PathwayBrowser/#/R-SSC-432121 LDL binds to LRP8 IEA Sus scrofa 16113 R-SSC-432129 https://reactome.org/PathwayBrowser/#/R-SSC-432129 FGR binds and phosphorylates LRP8 IEA Sus scrofa 16113 R-SSC-435244 https://reactome.org/PathwayBrowser/#/R-SSC-435244 PECAM1 is phosphorylated IEA Sus scrofa 16113 R-SSC-5250531 https://reactome.org/PathwayBrowser/#/R-SSC-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Sus scrofa 16113 R-SSC-5358340 https://reactome.org/PathwayBrowser/#/R-SSC-5358340 Autoproteolytic cleavage of Hh precursors IEA Sus scrofa 16113 R-SSC-6807055 https://reactome.org/PathwayBrowser/#/R-SSC-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Sus scrofa 16113 R-SSC-6813720 https://reactome.org/PathwayBrowser/#/R-SSC-6813720 NCEH1 hydrolyzes cholesterol esters IEA Sus scrofa 16113 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa 16113 R-SSC-8848053 https://reactome.org/PathwayBrowser/#/R-SSC-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Sus scrofa 16113 R-SSC-8858252 https://reactome.org/PathwayBrowser/#/R-SSC-8858252 HDLBP binds HDL IEA Sus scrofa 16113 R-SSC-8863471 https://reactome.org/PathwayBrowser/#/R-SSC-8863471 LDLR is bound by DAB2 and ARH IEA Sus scrofa 16113 R-SSC-8865667 https://reactome.org/PathwayBrowser/#/R-SSC-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Sus scrofa 16113 R-SSC-8866304 https://reactome.org/PathwayBrowser/#/R-SSC-8866304 pre-VLDL binds lipids to form VLDL IEA Sus scrofa 16113 R-SSC-8866327 https://reactome.org/PathwayBrowser/#/R-SSC-8866327 VLDL translocates from SER lumen to extracellular region IEA Sus scrofa 16113 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa 16113 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa 16113 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa 16113 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 16113 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa 16113 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa 16113 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 16113 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa 16113 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 16113 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa 16113 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa 16113 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 16113 R-SSC-8869667 https://reactome.org/PathwayBrowser/#/R-SSC-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Sus scrofa 16113 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 16113 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa 16113 R-SSC-8876366 https://reactome.org/PathwayBrowser/#/R-SSC-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Sus scrofa 16113 R-SSC-8876472 https://reactome.org/PathwayBrowser/#/R-SSC-8876472 NPC2 binds CHOL IEA Sus scrofa 16113 R-SSC-8876484 https://reactome.org/PathwayBrowser/#/R-SSC-8876484 NPC2 transfers CHOL to NPC1 IEA Sus scrofa 16113 R-SSC-8876485 https://reactome.org/PathwayBrowser/#/R-SSC-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Sus scrofa 16113 R-SSC-8876696 https://reactome.org/PathwayBrowser/#/R-SSC-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Sus scrofa 16113 R-SSC-8937442 https://reactome.org/PathwayBrowser/#/R-SSC-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Sus scrofa 16113 R-SSC-8948034 https://reactome.org/PathwayBrowser/#/R-SSC-8948034 FGR binds LDL:LRP8 IEA Sus scrofa 16113 R-SSC-8951850 https://reactome.org/PathwayBrowser/#/R-SSC-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Sus scrofa 16113 R-SSC-9707586 https://reactome.org/PathwayBrowser/#/R-SSC-9707586 FeHM oxidises LDL,HDL IEA Sus scrofa 16113 R-XTR-1454928 https://reactome.org/PathwayBrowser/#/R-XTR-1454928 ABCG4 may mediate cholesterol efflux IEA Xenopus tropicalis 16113 R-XTR-176609 https://reactome.org/PathwayBrowser/#/R-XTR-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Xenopus tropicalis 16113 R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 16113 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 16113 R-XTR-192061 https://reactome.org/PathwayBrowser/#/R-XTR-192061 CYP46A1 24-hydroxylates CHOL IEA Xenopus tropicalis 16113 R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 16113 R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 16113 R-XTR-196086 https://reactome.org/PathwayBrowser/#/R-XTR-196086 Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane IEA Xenopus tropicalis 16113 R-XTR-196126 https://reactome.org/PathwayBrowser/#/R-XTR-196126 CHOL translocates from cytosol to mitochondrial intermembrane space IEA Xenopus tropicalis 16113 R-XTR-196417 https://reactome.org/PathwayBrowser/#/R-XTR-196417 Reduction of desmosterol to cholesterol IEA Xenopus tropicalis 16113 R-XTR-264695 https://reactome.org/PathwayBrowser/#/R-XTR-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Xenopus tropicalis 16113 R-XTR-266082 https://reactome.org/PathwayBrowser/#/R-XTR-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Xenopus tropicalis 16113 R-XTR-5250531 https://reactome.org/PathwayBrowser/#/R-XTR-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Xenopus tropicalis 16113 R-XTR-5358340 https://reactome.org/PathwayBrowser/#/R-XTR-5358340 Autoproteolytic cleavage of Hh precursors IEA Xenopus tropicalis 16113 R-XTR-6807055 https://reactome.org/PathwayBrowser/#/R-XTR-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Xenopus tropicalis 16113 R-XTR-8848053 https://reactome.org/PathwayBrowser/#/R-XTR-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Xenopus tropicalis 16113 R-XTR-8876472 https://reactome.org/PathwayBrowser/#/R-XTR-8876472 NPC2 binds CHOL IEA Xenopus tropicalis 16113 R-XTR-8876484 https://reactome.org/PathwayBrowser/#/R-XTR-8876484 NPC2 transfers CHOL to NPC1 IEA Xenopus tropicalis 16113 R-XTR-8876485 https://reactome.org/PathwayBrowser/#/R-XTR-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Xenopus tropicalis 16113 R-XTR-8876696 https://reactome.org/PathwayBrowser/#/R-XTR-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Xenopus tropicalis 16119 R-MTU-964842 https://reactome.org/PathwayBrowser/#/R-MTU-964842 Shikimate results from hydration of DHS TAS Mycobacterium tuberculosis 16119 R-MTU-964939 https://reactome.org/PathwayBrowser/#/R-MTU-964939 Phosphorylation of shikimate TAS Mycobacterium tuberculosis 16125 R-BTA-390425 https://reactome.org/PathwayBrowser/#/R-BTA-390425 FAR1 reduces PalmCoA to HXOL IEA Bos taurus 16125 R-BTA-390427 https://reactome.org/PathwayBrowser/#/R-BTA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Bos taurus 16125 R-BTA-390438 https://reactome.org/PathwayBrowser/#/R-BTA-390438 FAR2 reduces PalmCoA to HXOL IEA Bos taurus 16125 R-BTA-8848582 https://reactome.org/PathwayBrowser/#/R-BTA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Bos taurus 16125 R-CEL-390425 https://reactome.org/PathwayBrowser/#/R-CEL-390425 FAR1 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 16125 R-CEL-390427 https://reactome.org/PathwayBrowser/#/R-CEL-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Caenorhabditis elegans 16125 R-CEL-390438 https://reactome.org/PathwayBrowser/#/R-CEL-390438 FAR2 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 16125 R-CEL-8848582 https://reactome.org/PathwayBrowser/#/R-CEL-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Caenorhabditis elegans 16125 R-CFA-390425 https://reactome.org/PathwayBrowser/#/R-CFA-390425 FAR1 reduces PalmCoA to HXOL IEA Canis familiaris 16125 R-CFA-390427 https://reactome.org/PathwayBrowser/#/R-CFA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Canis familiaris 16125 R-CFA-390438 https://reactome.org/PathwayBrowser/#/R-CFA-390438 FAR2 reduces PalmCoA to HXOL IEA Canis familiaris 16125 R-CFA-8848582 https://reactome.org/PathwayBrowser/#/R-CFA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Canis familiaris 16125 R-DDI-390425 https://reactome.org/PathwayBrowser/#/R-DDI-390425 FAR1 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 16125 R-DDI-390438 https://reactome.org/PathwayBrowser/#/R-DDI-390438 FAR2 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 16125 R-DDI-8848582 https://reactome.org/PathwayBrowser/#/R-DDI-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Dictyostelium discoideum 16125 R-DME-390425 https://reactome.org/PathwayBrowser/#/R-DME-390425 FAR1 reduces PalmCoA to HXOL IEA Drosophila melanogaster 16125 R-DME-390427 https://reactome.org/PathwayBrowser/#/R-DME-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Drosophila melanogaster 16125 R-DME-390438 https://reactome.org/PathwayBrowser/#/R-DME-390438 FAR2 reduces PalmCoA to HXOL IEA Drosophila melanogaster 16125 R-DME-8848582 https://reactome.org/PathwayBrowser/#/R-DME-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Drosophila melanogaster 16125 R-DRE-390438 https://reactome.org/PathwayBrowser/#/R-DRE-390438 FAR2 reduces PalmCoA to HXOL IEA Danio rerio 16125 R-DRE-8848582 https://reactome.org/PathwayBrowser/#/R-DRE-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Danio rerio 16125 R-GGA-390425 https://reactome.org/PathwayBrowser/#/R-GGA-390425 FAR1 reduces PalmCoA to HXOL IEA Gallus gallus 16125 R-GGA-390438 https://reactome.org/PathwayBrowser/#/R-GGA-390438 FAR2 reduces PalmCoA to HXOL IEA Gallus gallus 16125 R-GGA-8848582 https://reactome.org/PathwayBrowser/#/R-GGA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Gallus gallus 16125 R-HSA-390425 https://reactome.org/PathwayBrowser/#/R-HSA-390425 FAR1 reduces PalmCoA to HXOL TAS Homo sapiens 16125 R-HSA-390427 https://reactome.org/PathwayBrowser/#/R-HSA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate TAS Homo sapiens 16125 R-HSA-390438 https://reactome.org/PathwayBrowser/#/R-HSA-390438 FAR2 reduces PalmCoA to HXOL TAS Homo sapiens 16125 R-HSA-8848582 https://reactome.org/PathwayBrowser/#/R-HSA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester TAS Homo sapiens 16125 R-HSA-8848586 https://reactome.org/PathwayBrowser/#/R-HSA-8848586 Transport of cytosolic HXOL to the peroxisome TAS Homo sapiens 16125 R-MMU-390425 https://reactome.org/PathwayBrowser/#/R-MMU-390425 FAR1 reduces PalmCoA to HXOL IEA Mus musculus 16125 R-MMU-390427 https://reactome.org/PathwayBrowser/#/R-MMU-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Mus musculus 16125 R-MMU-390438 https://reactome.org/PathwayBrowser/#/R-MMU-390438 FAR2 reduces PalmCoA to HXOL IEA Mus musculus 16125 R-MMU-8848582 https://reactome.org/PathwayBrowser/#/R-MMU-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Mus musculus 16125 R-RNO-390425 https://reactome.org/PathwayBrowser/#/R-RNO-390425 FAR1 reduces PalmCoA to HXOL IEA Rattus norvegicus 16125 R-RNO-390427 https://reactome.org/PathwayBrowser/#/R-RNO-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Rattus norvegicus 16125 R-RNO-390438 https://reactome.org/PathwayBrowser/#/R-RNO-390438 FAR2 reduces PalmCoA to HXOL IEA Rattus norvegicus 16125 R-RNO-8848582 https://reactome.org/PathwayBrowser/#/R-RNO-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Rattus norvegicus 16125 R-SCE-8848582 https://reactome.org/PathwayBrowser/#/R-SCE-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Saccharomyces cerevisiae 16125 R-SPO-8848582 https://reactome.org/PathwayBrowser/#/R-SPO-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Schizosaccharomyces pombe 16125 R-SSC-390425 https://reactome.org/PathwayBrowser/#/R-SSC-390425 FAR1 reduces PalmCoA to HXOL IEA Sus scrofa 16125 R-SSC-390427 https://reactome.org/PathwayBrowser/#/R-SSC-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Sus scrofa 16125 R-SSC-390438 https://reactome.org/PathwayBrowser/#/R-SSC-390438 FAR2 reduces PalmCoA to HXOL IEA Sus scrofa 16125 R-SSC-8848582 https://reactome.org/PathwayBrowser/#/R-SSC-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Sus scrofa 16125 R-XTR-390427 https://reactome.org/PathwayBrowser/#/R-XTR-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Xenopus tropicalis 16125 R-XTR-8848582 https://reactome.org/PathwayBrowser/#/R-XTR-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Xenopus tropicalis 16134 R-BTA-1183128 https://reactome.org/PathwayBrowser/#/R-BTA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Bos taurus 16134 R-BTA-141200 https://reactome.org/PathwayBrowser/#/R-BTA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Bos taurus 16134 R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus 16134 R-BTA-1614583 https://reactome.org/PathwayBrowser/#/R-BTA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Bos taurus 16134 R-BTA-1614631 https://reactome.org/PathwayBrowser/#/R-BTA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Bos taurus 16134 R-BTA-2002466 https://reactome.org/PathwayBrowser/#/R-BTA-2002466 Formation of allysine by LOX IEA Bos taurus 16134 R-BTA-2160492 https://reactome.org/PathwayBrowser/#/R-BTA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Bos taurus 16134 R-BTA-2395340 https://reactome.org/PathwayBrowser/#/R-BTA-2395340 Formation of hydroxyallysine by LOX IEA Bos taurus 16134 R-BTA-3247569 https://reactome.org/PathwayBrowser/#/R-BTA-3247569 PADI4 deiminates Histones IEA Bos taurus 16134 R-BTA-374909 https://reactome.org/PathwayBrowser/#/R-BTA-374909 Catabolism of Noradrenaline IEA Bos taurus 16134 R-BTA-379382 https://reactome.org/PathwayBrowser/#/R-BTA-379382 MAOA:FAD deaminates DA to DOPAC IEA Bos taurus 16134 R-BTA-379395 https://reactome.org/PathwayBrowser/#/R-BTA-379395 MAOA:FAD deaminates 3MT to HVA IEA Bos taurus 16134 R-BTA-5693346 https://reactome.org/PathwayBrowser/#/R-BTA-5693346 CECRI deaminates Ade-Rib to Ino IEA Bos taurus 16134 R-BTA-5693977 https://reactome.org/PathwayBrowser/#/R-BTA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Bos taurus 16134 R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 16134 R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 16134 R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 16134 R-BTA-5696408 https://reactome.org/PathwayBrowser/#/R-BTA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Bos taurus 16134 R-BTA-5696415 https://reactome.org/PathwayBrowser/#/R-BTA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Bos taurus 16134 R-BTA-6797627 https://reactome.org/PathwayBrowser/#/R-BTA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Bos taurus 16134 R-BTA-77614 https://reactome.org/PathwayBrowser/#/R-BTA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Bos taurus 16134 R-BTA-77615 https://reactome.org/PathwayBrowser/#/R-BTA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Bos taurus 16134 R-BTA-83677 https://reactome.org/PathwayBrowser/#/R-BTA-83677 C4 deamination of cytidine IEA Bos taurus 16134 R-BTA-9014641 https://reactome.org/PathwayBrowser/#/R-BTA-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Bos taurus 16134 R-BTA-9014741 https://reactome.org/PathwayBrowser/#/R-BTA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Bos taurus 16134 R-BTA-9034539 https://reactome.org/PathwayBrowser/#/R-BTA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Bos taurus 16134 R-CEL-1614583 https://reactome.org/PathwayBrowser/#/R-CEL-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Caenorhabditis elegans 16134 R-CEL-1614631 https://reactome.org/PathwayBrowser/#/R-CEL-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Caenorhabditis elegans 16134 R-CEL-5693977 https://reactome.org/PathwayBrowser/#/R-CEL-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Caenorhabditis elegans 16134 R-CEL-5696408 https://reactome.org/PathwayBrowser/#/R-CEL-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Caenorhabditis elegans 16134 R-CEL-5696415 https://reactome.org/PathwayBrowser/#/R-CEL-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Caenorhabditis elegans 16134 R-CEL-6797627 https://reactome.org/PathwayBrowser/#/R-CEL-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Caenorhabditis elegans 16134 R-CEL-77615 https://reactome.org/PathwayBrowser/#/R-CEL-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Caenorhabditis elegans 16134 R-CEL-9014641 https://reactome.org/PathwayBrowser/#/R-CEL-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Caenorhabditis elegans 16134 R-CEL-9014741 https://reactome.org/PathwayBrowser/#/R-CEL-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Caenorhabditis elegans 16134 R-CEL-9034539 https://reactome.org/PathwayBrowser/#/R-CEL-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Caenorhabditis elegans 16134 R-CFA-1183128 https://reactome.org/PathwayBrowser/#/R-CFA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Canis familiaris 16134 R-CFA-141200 https://reactome.org/PathwayBrowser/#/R-CFA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Canis familiaris 16134 R-CFA-141202 https://reactome.org/PathwayBrowser/#/R-CFA-141202 MAOB:FAD oxidatively deaminates TYR IEA Canis familiaris 16134 R-CFA-1614583 https://reactome.org/PathwayBrowser/#/R-CFA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Canis familiaris 16134 R-CFA-1614631 https://reactome.org/PathwayBrowser/#/R-CFA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Canis familiaris 16134 R-CFA-2002466 https://reactome.org/PathwayBrowser/#/R-CFA-2002466 Formation of allysine by LOX IEA Canis familiaris 16134 R-CFA-2160492 https://reactome.org/PathwayBrowser/#/R-CFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Canis familiaris 16134 R-CFA-2395340 https://reactome.org/PathwayBrowser/#/R-CFA-2395340 Formation of hydroxyallysine by LOX IEA Canis familiaris 16134 R-CFA-3247569 https://reactome.org/PathwayBrowser/#/R-CFA-3247569 PADI4 deiminates Histones IEA Canis familiaris 16134 R-CFA-374909 https://reactome.org/PathwayBrowser/#/R-CFA-374909 Catabolism of Noradrenaline IEA Canis familiaris 16134 R-CFA-379382 https://reactome.org/PathwayBrowser/#/R-CFA-379382 MAOA:FAD deaminates DA to DOPAC IEA Canis familiaris 16134 R-CFA-379395 https://reactome.org/PathwayBrowser/#/R-CFA-379395 MAOA:FAD deaminates 3MT to HVA IEA Canis familiaris 16134 R-CFA-5693977 https://reactome.org/PathwayBrowser/#/R-CFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Canis familiaris 16134 R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 16134 R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 16134 R-CFA-5696408 https://reactome.org/PathwayBrowser/#/R-CFA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Canis familiaris 16134 R-CFA-5696415 https://reactome.org/PathwayBrowser/#/R-CFA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Canis familiaris 16134 R-CFA-6797627 https://reactome.org/PathwayBrowser/#/R-CFA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Canis familiaris 16134 R-CFA-77614 https://reactome.org/PathwayBrowser/#/R-CFA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Canis familiaris 16134 R-CFA-77615 https://reactome.org/PathwayBrowser/#/R-CFA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Canis familiaris 16134 R-CFA-83677 https://reactome.org/PathwayBrowser/#/R-CFA-83677 C4 deamination of cytidine IEA Canis familiaris 16134 R-CFA-9014641 https://reactome.org/PathwayBrowser/#/R-CFA-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Canis familiaris 16134 R-CFA-9014741 https://reactome.org/PathwayBrowser/#/R-CFA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Canis familiaris 16134 R-CFA-9034539 https://reactome.org/PathwayBrowser/#/R-CFA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Canis familiaris 16134 R-DDI-141200 https://reactome.org/PathwayBrowser/#/R-DDI-141200 MAOB:FAD oxidatively deaminates of PEA IEA Dictyostelium discoideum 16134 R-DDI-141202 https://reactome.org/PathwayBrowser/#/R-DDI-141202 MAOB:FAD oxidatively deaminates TYR IEA Dictyostelium discoideum 16134 R-DDI-1614583 https://reactome.org/PathwayBrowser/#/R-DDI-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Dictyostelium discoideum 16134 R-DDI-1614631 https://reactome.org/PathwayBrowser/#/R-DDI-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Dictyostelium discoideum 16134 R-DDI-2160492 https://reactome.org/PathwayBrowser/#/R-DDI-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Dictyostelium discoideum 16134 R-DDI-374909 https://reactome.org/PathwayBrowser/#/R-DDI-374909 Catabolism of Noradrenaline IEA Dictyostelium discoideum 16134 R-DDI-379382 https://reactome.org/PathwayBrowser/#/R-DDI-379382 MAOA:FAD deaminates DA to DOPAC IEA Dictyostelium discoideum 16134 R-DDI-379395 https://reactome.org/PathwayBrowser/#/R-DDI-379395 MAOA:FAD deaminates 3MT to HVA IEA Dictyostelium discoideum 16134 R-DDI-5693346 https://reactome.org/PathwayBrowser/#/R-DDI-5693346 CECRI deaminates Ade-Rib to Ino IEA Dictyostelium discoideum 16134 R-DDI-5693977 https://reactome.org/PathwayBrowser/#/R-DDI-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Dictyostelium discoideum 16134 R-DDI-6797627 https://reactome.org/PathwayBrowser/#/R-DDI-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Dictyostelium discoideum 16134 R-DDI-9014641 https://reactome.org/PathwayBrowser/#/R-DDI-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Dictyostelium discoideum 16134 R-DDI-9014741 https://reactome.org/PathwayBrowser/#/R-DDI-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Dictyostelium discoideum 16134 R-DDI-9034539 https://reactome.org/PathwayBrowser/#/R-DDI-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Dictyostelium discoideum 16134 R-DME-1614583 https://reactome.org/PathwayBrowser/#/R-DME-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Drosophila melanogaster 16134 R-DME-1614631 https://reactome.org/PathwayBrowser/#/R-DME-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Drosophila melanogaster 16134 R-DME-5693346 https://reactome.org/PathwayBrowser/#/R-DME-5693346 CECRI deaminates Ade-Rib to Ino IEA Drosophila melanogaster 16134 R-DME-5693977 https://reactome.org/PathwayBrowser/#/R-DME-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Drosophila melanogaster 16134 R-DME-5696408 https://reactome.org/PathwayBrowser/#/R-DME-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Drosophila melanogaster 16134 R-DME-5696415 https://reactome.org/PathwayBrowser/#/R-DME-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Drosophila melanogaster 16134 R-DME-6797627 https://reactome.org/PathwayBrowser/#/R-DME-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Drosophila melanogaster 16134 R-DME-77615 https://reactome.org/PathwayBrowser/#/R-DME-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Drosophila melanogaster 16134 R-DME-9014641 https://reactome.org/PathwayBrowser/#/R-DME-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Drosophila melanogaster 16134 R-DRE-141200 https://reactome.org/PathwayBrowser/#/R-DRE-141200 MAOB:FAD oxidatively deaminates of PEA IEA Danio rerio 16134 R-DRE-141202 https://reactome.org/PathwayBrowser/#/R-DRE-141202 MAOB:FAD oxidatively deaminates TYR IEA Danio rerio 16134 R-DRE-1614583 https://reactome.org/PathwayBrowser/#/R-DRE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Danio rerio 16134 R-DRE-1614631 https://reactome.org/PathwayBrowser/#/R-DRE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Danio rerio 16134 R-DRE-2002466 https://reactome.org/PathwayBrowser/#/R-DRE-2002466 Formation of allysine by LOX IEA Danio rerio 16134 R-DRE-2395340 https://reactome.org/PathwayBrowser/#/R-DRE-2395340 Formation of hydroxyallysine by LOX IEA Danio rerio 16134 R-DRE-5693346 https://reactome.org/PathwayBrowser/#/R-DRE-5693346 CECRI deaminates Ade-Rib to Ino IEA Danio rerio 16134 R-DRE-5693977 https://reactome.org/PathwayBrowser/#/R-DRE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Danio rerio 16134 R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 16134 R-DRE-5696408 https://reactome.org/PathwayBrowser/#/R-DRE-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Danio rerio 16134 R-DRE-5696415 https://reactome.org/PathwayBrowser/#/R-DRE-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Danio rerio 16134 R-DRE-9014641 https://reactome.org/PathwayBrowser/#/R-DRE-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Danio rerio 16134 R-GGA-1183128 https://reactome.org/PathwayBrowser/#/R-GGA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Gallus gallus 16134 R-GGA-141200 https://reactome.org/PathwayBrowser/#/R-GGA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Gallus gallus 16134 R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus 16134 R-GGA-1614583 https://reactome.org/PathwayBrowser/#/R-GGA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Gallus gallus 16134 R-GGA-1614631 https://reactome.org/PathwayBrowser/#/R-GGA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Gallus gallus 16134 R-GGA-2002466 https://reactome.org/PathwayBrowser/#/R-GGA-2002466 Formation of allysine by LOX IEA Gallus gallus 16134 R-GGA-2395340 https://reactome.org/PathwayBrowser/#/R-GGA-2395340 Formation of hydroxyallysine by LOX IEA Gallus gallus 16134 R-GGA-374909 https://reactome.org/PathwayBrowser/#/R-GGA-374909 Catabolism of Noradrenaline IEA Gallus gallus 16134 R-GGA-379382 https://reactome.org/PathwayBrowser/#/R-GGA-379382 MAOA:FAD deaminates DA to DOPAC IEA Gallus gallus 16134 R-GGA-379395 https://reactome.org/PathwayBrowser/#/R-GGA-379395 MAOA:FAD deaminates 3MT to HVA IEA Gallus gallus 16134 R-GGA-421439 https://reactome.org/PathwayBrowser/#/R-GGA-421439 4 porphobilinogen + H2O => hydroxymethylbilane + 4 NH3 IEA Gallus gallus 16134 R-GGA-5693346 https://reactome.org/PathwayBrowser/#/R-GGA-5693346 CECRI deaminates Ade-Rib to Ino IEA Gallus gallus 16134 R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 16134 R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 16134 R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 16134 R-GGA-5696408 https://reactome.org/PathwayBrowser/#/R-GGA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Gallus gallus 16134 R-GGA-5696415 https://reactome.org/PathwayBrowser/#/R-GGA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Gallus gallus 16134 R-GGA-6797627 https://reactome.org/PathwayBrowser/#/R-GGA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Gallus gallus 16134 R-GGA-77614 https://reactome.org/PathwayBrowser/#/R-GGA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Gallus gallus 16134 R-GGA-9014641 https://reactome.org/PathwayBrowser/#/R-GGA-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Gallus gallus 16134 R-GGA-9014741 https://reactome.org/PathwayBrowser/#/R-GGA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Gallus gallus 16134 R-GGA-9034539 https://reactome.org/PathwayBrowser/#/R-GGA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Gallus gallus 16134 R-HSA-1183128 https://reactome.org/PathwayBrowser/#/R-HSA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins TAS Homo sapiens 16134 R-HSA-1222583 https://reactome.org/PathwayBrowser/#/R-HSA-1222583 MscR reduces nitrosomycothiol to ammonia TAS Homo sapiens 16134 R-HSA-141200 https://reactome.org/PathwayBrowser/#/R-HSA-141200 MAOB:FAD oxidatively deaminates of PEA TAS Homo sapiens 16134 R-HSA-141202 https://reactome.org/PathwayBrowser/#/R-HSA-141202 MAOB:FAD oxidatively deaminates TYR TAS Homo sapiens 16134 R-HSA-1614583 https://reactome.org/PathwayBrowser/#/R-HSA-1614583 PXLP-K212-CTH cleaves L-Cystathionine TAS Homo sapiens 16134 R-HSA-1614631 https://reactome.org/PathwayBrowser/#/R-HSA-1614631 Homocysteine is degraded to oxobutanoate and H2S TAS Homo sapiens 16134 R-HSA-180632 https://reactome.org/PathwayBrowser/#/R-HSA-180632 Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand TAS Homo sapiens 16134 R-HSA-2002466 https://reactome.org/PathwayBrowser/#/R-HSA-2002466 Formation of allysine by LOX TAS Homo sapiens 16134 R-HSA-2160492 https://reactome.org/PathwayBrowser/#/R-HSA-2160492 IL4I1:FAD oxidises L-Phe to kPPV TAS Homo sapiens 16134 R-HSA-2395340 https://reactome.org/PathwayBrowser/#/R-HSA-2395340 Formation of hydroxyallysine by LOX TAS Homo sapiens 16134 R-HSA-2408537 https://reactome.org/PathwayBrowser/#/R-HSA-2408537 Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH IEA Homo sapiens 16134 R-HSA-2408539 https://reactome.org/PathwayBrowser/#/R-HSA-2408539 MeSec is hydrolysed to MeSeH by PXLP-K212-CTH IEA Homo sapiens 16134 R-HSA-2408543 https://reactome.org/PathwayBrowser/#/R-HSA-2408543 SeCysta is hydrolysed to Sec by PXLP-K212-CTH IEA Homo sapiens 16134 R-HSA-3247569 https://reactome.org/PathwayBrowser/#/R-HSA-3247569 PADI4 deiminates Histones TAS Homo sapiens 16134 R-HSA-374909 https://reactome.org/PathwayBrowser/#/R-HSA-374909 Catabolism of Noradrenaline TAS Homo sapiens 16134 R-HSA-379382 https://reactome.org/PathwayBrowser/#/R-HSA-379382 MAOA:FAD deaminates DA to DOPAC TAS Homo sapiens 16134 R-HSA-379395 https://reactome.org/PathwayBrowser/#/R-HSA-379395 MAOA:FAD deaminates 3MT to HVA TAS Homo sapiens 16134 R-HSA-5693346 https://reactome.org/PathwayBrowser/#/R-HSA-5693346 CECRI deaminates Ade-Rib to Ino TAS Homo sapiens 16134 R-HSA-5693977 https://reactome.org/PathwayBrowser/#/R-HSA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF TAS Homo sapiens 16134 R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 16134 R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 16134 R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 16134 R-HSA-5696408 https://reactome.org/PathwayBrowser/#/R-HSA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL TAS Homo sapiens 16134 R-HSA-5696415 https://reactome.org/PathwayBrowser/#/R-HSA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA TAS Homo sapiens 16134 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 16134 R-HSA-6782336 https://reactome.org/PathwayBrowser/#/R-HSA-6782336 ADAT1 deaminates adenosine-37 in tRNA(Ala) IEA Homo sapiens 16134 R-HSA-6797627 https://reactome.org/PathwayBrowser/#/R-HSA-6797627 ASPG hydrolyses L-Asn to L-Asp TAS Homo sapiens 16134 R-HSA-77614 https://reactome.org/PathwayBrowser/#/R-HSA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) TAS Homo sapiens 16134 R-HSA-77615 https://reactome.org/PathwayBrowser/#/R-HSA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) TAS Homo sapiens 16134 R-HSA-83677 https://reactome.org/PathwayBrowser/#/R-HSA-83677 C4 deamination of cytidine TAS Homo sapiens 16134 R-HSA-9014641 https://reactome.org/PathwayBrowser/#/R-HSA-9014641 HRSP12 deaminates 2AA to 2OBUTA TAS Homo sapiens 16134 R-HSA-9014741 https://reactome.org/PathwayBrowser/#/R-HSA-9014741 PXLP-K56-SRR dimer deaminates D-Ser TAS Homo sapiens 16134 R-HSA-9034539 https://reactome.org/PathwayBrowser/#/R-HSA-9034539 PXLP-K56-SRR dimer deaminates L-Ser TAS Homo sapiens 16134 R-MMU-1183128 https://reactome.org/PathwayBrowser/#/R-MMU-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Mus musculus 16134 R-MMU-141200 https://reactome.org/PathwayBrowser/#/R-MMU-141200 MAOB:FAD oxidatively deaminates of PEA IEA Mus musculus 16134 R-MMU-141202 https://reactome.org/PathwayBrowser/#/R-MMU-141202 MAOB:FAD oxidatively deaminates TYR IEA Mus musculus 16134 R-MMU-1614583 https://reactome.org/PathwayBrowser/#/R-MMU-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Mus musculus 16134 R-MMU-1614631 https://reactome.org/PathwayBrowser/#/R-MMU-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Mus musculus 16134 R-MMU-2002466 https://reactome.org/PathwayBrowser/#/R-MMU-2002466 Formation of allysine by LOX IEA Mus musculus 16134 R-MMU-2160492 https://reactome.org/PathwayBrowser/#/R-MMU-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Mus musculus 16134 R-MMU-2395340 https://reactome.org/PathwayBrowser/#/R-MMU-2395340 Formation of hydroxyallysine by LOX IEA Mus musculus 16134 R-MMU-2408528 https://reactome.org/PathwayBrowser/#/R-MMU-2408528 Excess SeMet is cleaved into MeSeH by PXLP-K211-Cth TAS Mus musculus 16134 R-MMU-3247569 https://reactome.org/PathwayBrowser/#/R-MMU-3247569 PADI4 deiminates Histones IEA Mus musculus 16134 R-MMU-374909 https://reactome.org/PathwayBrowser/#/R-MMU-374909 Catabolism of Noradrenaline IEA Mus musculus 16134 R-MMU-379382 https://reactome.org/PathwayBrowser/#/R-MMU-379382 MAOA:FAD deaminates DA to DOPAC IEA Mus musculus 16134 R-MMU-379395 https://reactome.org/PathwayBrowser/#/R-MMU-379395 MAOA:FAD deaminates 3MT to HVA IEA Mus musculus 16134 R-MMU-5693977 https://reactome.org/PathwayBrowser/#/R-MMU-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Mus musculus 16134 R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 16134 R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 16134 R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 16134 R-MMU-5696408 https://reactome.org/PathwayBrowser/#/R-MMU-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Mus musculus 16134 R-MMU-5696415 https://reactome.org/PathwayBrowser/#/R-MMU-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Mus musculus 16134 R-MMU-6797627 https://reactome.org/PathwayBrowser/#/R-MMU-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Mus musculus 16134 R-MMU-77614 https://reactome.org/PathwayBrowser/#/R-MMU-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Mus musculus 16134 R-MMU-77615 https://reactome.org/PathwayBrowser/#/R-MMU-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Mus musculus 16134 R-MMU-83677 https://reactome.org/PathwayBrowser/#/R-MMU-83677 C4 deamination of cytidine IEA Mus musculus 16134 R-MMU-9014641 https://reactome.org/PathwayBrowser/#/R-MMU-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Mus musculus 16134 R-MMU-9014741 https://reactome.org/PathwayBrowser/#/R-MMU-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Mus musculus 16134 R-MMU-9034539 https://reactome.org/PathwayBrowser/#/R-MMU-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Mus musculus 16134 R-MMU-9817520 https://reactome.org/PathwayBrowser/#/R-MMU-9817520 Aicda deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine TAS Mus musculus 16134 R-MTU-937192 https://reactome.org/PathwayBrowser/#/R-MTU-937192 Cysteine from cystathionine and vice versa TAS Mycobacterium tuberculosis 16134 R-PFA-2160492 https://reactome.org/PathwayBrowser/#/R-PFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Plasmodium falciparum 16134 R-PFA-5693977 https://reactome.org/PathwayBrowser/#/R-PFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Plasmodium falciparum 16134 R-RNO-1183128 https://reactome.org/PathwayBrowser/#/R-RNO-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Rattus norvegicus 16134 R-RNO-141200 https://reactome.org/PathwayBrowser/#/R-RNO-141200 MAOB:FAD oxidatively deaminates of PEA IEA Rattus norvegicus 16134 R-RNO-141202 https://reactome.org/PathwayBrowser/#/R-RNO-141202 MAOB:FAD oxidatively deaminates TYR IEA Rattus norvegicus 16134 R-RNO-1614583 https://reactome.org/PathwayBrowser/#/R-RNO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Rattus norvegicus 16134 R-RNO-1614631 https://reactome.org/PathwayBrowser/#/R-RNO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Rattus norvegicus 16134 R-RNO-2002466 https://reactome.org/PathwayBrowser/#/R-RNO-2002466 Formation of allysine by LOX IEA Rattus norvegicus 16134 R-RNO-2160492 https://reactome.org/PathwayBrowser/#/R-RNO-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Rattus norvegicus 16134 R-RNO-2395340 https://reactome.org/PathwayBrowser/#/R-RNO-2395340 Formation of hydroxyallysine by LOX IEA Rattus norvegicus 16134 R-RNO-2408502 https://reactome.org/PathwayBrowser/#/R-RNO-2408502 SeCysta is hydrolysed to Sec by PXLP-K211-Cth TAS Rattus norvegicus 16134 R-RNO-2408538 https://reactome.org/PathwayBrowser/#/R-RNO-2408538 MeSec is hydrolysed to MeSeH by PXLP-K211-Cth TAS Rattus norvegicus 16134 R-RNO-3247569 https://reactome.org/PathwayBrowser/#/R-RNO-3247569 PADI4 deiminates Histones IEA Rattus norvegicus 16134 R-RNO-374909 https://reactome.org/PathwayBrowser/#/R-RNO-374909 Catabolism of Noradrenaline IEA Rattus norvegicus 16134 R-RNO-379382 https://reactome.org/PathwayBrowser/#/R-RNO-379382 MAOA:FAD deaminates DA to DOPAC IEA Rattus norvegicus 16134 R-RNO-379395 https://reactome.org/PathwayBrowser/#/R-RNO-379395 MAOA:FAD deaminates 3MT to HVA IEA Rattus norvegicus 16134 R-RNO-5693977 https://reactome.org/PathwayBrowser/#/R-RNO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Rattus norvegicus 16134 R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 16134 R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 16134 R-RNO-5696408 https://reactome.org/PathwayBrowser/#/R-RNO-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Rattus norvegicus 16134 R-RNO-5696415 https://reactome.org/PathwayBrowser/#/R-RNO-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Rattus norvegicus 16134 R-RNO-6797627 https://reactome.org/PathwayBrowser/#/R-RNO-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Rattus norvegicus 16134 R-RNO-77614 https://reactome.org/PathwayBrowser/#/R-RNO-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Rattus norvegicus 16134 R-RNO-77615 https://reactome.org/PathwayBrowser/#/R-RNO-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Rattus norvegicus 16134 R-RNO-83677 https://reactome.org/PathwayBrowser/#/R-RNO-83677 C4 deamination of cytidine IEA Rattus norvegicus 16134 R-RNO-9014641 https://reactome.org/PathwayBrowser/#/R-RNO-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Rattus norvegicus 16134 R-RNO-9014741 https://reactome.org/PathwayBrowser/#/R-RNO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Rattus norvegicus 16134 R-RNO-9034539 https://reactome.org/PathwayBrowser/#/R-RNO-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Rattus norvegicus 16134 R-SCE-1614583 https://reactome.org/PathwayBrowser/#/R-SCE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Saccharomyces cerevisiae 16134 R-SCE-1614631 https://reactome.org/PathwayBrowser/#/R-SCE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Saccharomyces cerevisiae 16134 R-SCE-5693977 https://reactome.org/PathwayBrowser/#/R-SCE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Saccharomyces cerevisiae 16134 R-SCE-6790128 https://reactome.org/PathwayBrowser/#/R-SCE-6790128 TAD1 deaminates adenosine-37 in tRNA(Ala) yielding inosine-37 TAS Saccharomyces cerevisiae 16134 R-SCE-9014641 https://reactome.org/PathwayBrowser/#/R-SCE-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Saccharomyces cerevisiae 16134 R-SCE-9014741 https://reactome.org/PathwayBrowser/#/R-SCE-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Saccharomyces cerevisiae 16134 R-SCE-9034539 https://reactome.org/PathwayBrowser/#/R-SCE-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Saccharomyces cerevisiae 16134 R-SPO-1614583 https://reactome.org/PathwayBrowser/#/R-SPO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Schizosaccharomyces pombe 16134 R-SPO-1614631 https://reactome.org/PathwayBrowser/#/R-SPO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Schizosaccharomyces pombe 16134 R-SPO-5693977 https://reactome.org/PathwayBrowser/#/R-SPO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Schizosaccharomyces pombe 16134 R-SPO-9014641 https://reactome.org/PathwayBrowser/#/R-SPO-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Schizosaccharomyces pombe 16134 R-SPO-9014741 https://reactome.org/PathwayBrowser/#/R-SPO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Schizosaccharomyces pombe 16134 R-SPO-9034539 https://reactome.org/PathwayBrowser/#/R-SPO-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Schizosaccharomyces pombe 16134 R-SSC-1183128 https://reactome.org/PathwayBrowser/#/R-SSC-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Sus scrofa 16134 R-SSC-141200 https://reactome.org/PathwayBrowser/#/R-SSC-141200 MAOB:FAD oxidatively deaminates of PEA IEA Sus scrofa 16134 R-SSC-141202 https://reactome.org/PathwayBrowser/#/R-SSC-141202 MAOB:FAD oxidatively deaminates TYR IEA Sus scrofa 16134 R-SSC-1614583 https://reactome.org/PathwayBrowser/#/R-SSC-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Sus scrofa 16134 R-SSC-1614631 https://reactome.org/PathwayBrowser/#/R-SSC-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Sus scrofa 16134 R-SSC-2002466 https://reactome.org/PathwayBrowser/#/R-SSC-2002466 Formation of allysine by LOX IEA Sus scrofa 16134 R-SSC-2160492 https://reactome.org/PathwayBrowser/#/R-SSC-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Sus scrofa 16134 R-SSC-2395340 https://reactome.org/PathwayBrowser/#/R-SSC-2395340 Formation of hydroxyallysine by LOX IEA Sus scrofa 16134 R-SSC-3247569 https://reactome.org/PathwayBrowser/#/R-SSC-3247569 PADI4 deiminates Histones IEA Sus scrofa 16134 R-SSC-374909 https://reactome.org/PathwayBrowser/#/R-SSC-374909 Catabolism of Noradrenaline IEA Sus scrofa 16134 R-SSC-379382 https://reactome.org/PathwayBrowser/#/R-SSC-379382 MAOA:FAD deaminates DA to DOPAC IEA Sus scrofa 16134 R-SSC-379395 https://reactome.org/PathwayBrowser/#/R-SSC-379395 MAOA:FAD deaminates 3MT to HVA IEA Sus scrofa 16134 R-SSC-5693346 https://reactome.org/PathwayBrowser/#/R-SSC-5693346 CECRI deaminates Ade-Rib to Ino IEA Sus scrofa 16134 R-SSC-5693977 https://reactome.org/PathwayBrowser/#/R-SSC-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Sus scrofa 16134 R-SSC-5696131 https://reactome.org/PathwayBrowser/#/R-SSC-5696131 AOC1 deaminates Hist IEA Sus scrofa 16134 R-SSC-5696146 https://reactome.org/PathwayBrowser/#/R-SSC-5696146 AOC2 deaminates TYR IEA Sus scrofa 16134 R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa 16134 R-SSC-5696408 https://reactome.org/PathwayBrowser/#/R-SSC-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Sus scrofa 16134 R-SSC-5696415 https://reactome.org/PathwayBrowser/#/R-SSC-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Sus scrofa 16134 R-SSC-6797627 https://reactome.org/PathwayBrowser/#/R-SSC-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Sus scrofa 16134 R-SSC-77614 https://reactome.org/PathwayBrowser/#/R-SSC-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Sus scrofa 16134 R-SSC-77615 https://reactome.org/PathwayBrowser/#/R-SSC-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Sus scrofa 16134 R-SSC-83677 https://reactome.org/PathwayBrowser/#/R-SSC-83677 C4 deamination of cytidine IEA Sus scrofa 16134 R-SSC-9014641 https://reactome.org/PathwayBrowser/#/R-SSC-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Sus scrofa 16134 R-SSC-9014741 https://reactome.org/PathwayBrowser/#/R-SSC-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Sus scrofa 16134 R-SSC-9034539 https://reactome.org/PathwayBrowser/#/R-SSC-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Sus scrofa 16134 R-XTR-1183128 https://reactome.org/PathwayBrowser/#/R-XTR-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Xenopus tropicalis 16134 R-XTR-141200 https://reactome.org/PathwayBrowser/#/R-XTR-141200 MAOB:FAD oxidatively deaminates of PEA IEA Xenopus tropicalis 16134 R-XTR-141202 https://reactome.org/PathwayBrowser/#/R-XTR-141202 MAOB:FAD oxidatively deaminates TYR IEA Xenopus tropicalis 16134 R-XTR-1614583 https://reactome.org/PathwayBrowser/#/R-XTR-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Xenopus tropicalis 16134 R-XTR-1614631 https://reactome.org/PathwayBrowser/#/R-XTR-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Xenopus tropicalis 16134 R-XTR-2002466 https://reactome.org/PathwayBrowser/#/R-XTR-2002466 Formation of allysine by LOX IEA Xenopus tropicalis 16134 R-XTR-2160492 https://reactome.org/PathwayBrowser/#/R-XTR-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Xenopus tropicalis 16134 R-XTR-2395340 https://reactome.org/PathwayBrowser/#/R-XTR-2395340 Formation of hydroxyallysine by LOX IEA Xenopus tropicalis 16134 R-XTR-5693346 https://reactome.org/PathwayBrowser/#/R-XTR-5693346 CECRI deaminates Ade-Rib to Ino IEA Xenopus tropicalis 16134 R-XTR-5693977 https://reactome.org/PathwayBrowser/#/R-XTR-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Xenopus tropicalis 16134 R-XTR-5696131 https://reactome.org/PathwayBrowser/#/R-XTR-5696131 AOC1 deaminates Hist IEA Xenopus tropicalis 16134 R-XTR-5696183 https://reactome.org/PathwayBrowser/#/R-XTR-5696183 AOC3 deaminates BZAM IEA Xenopus tropicalis 16134 R-XTR-5696415 https://reactome.org/PathwayBrowser/#/R-XTR-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Xenopus tropicalis 16134 R-XTR-6797627 https://reactome.org/PathwayBrowser/#/R-XTR-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Xenopus tropicalis 16134 R-XTR-77615 https://reactome.org/PathwayBrowser/#/R-XTR-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Xenopus tropicalis 16134 R-XTR-9014641 https://reactome.org/PathwayBrowser/#/R-XTR-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Xenopus tropicalis 16134 R-XTR-9014741 https://reactome.org/PathwayBrowser/#/R-XTR-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Xenopus tropicalis 16134 R-XTR-9034539 https://reactome.org/PathwayBrowser/#/R-XTR-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Xenopus tropicalis 16144 R-CEL-8959510 https://reactome.org/PathwayBrowser/#/R-CEL-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Caenorhabditis elegans 16144 R-CFA-8959510 https://reactome.org/PathwayBrowser/#/R-CFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Canis familiaris 16144 R-DDI-8959510 https://reactome.org/PathwayBrowser/#/R-DDI-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Dictyostelium discoideum 16144 R-DME-8959510 https://reactome.org/PathwayBrowser/#/R-DME-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Drosophila melanogaster 16144 R-DRE-8959510 https://reactome.org/PathwayBrowser/#/R-DRE-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Danio rerio 16144 R-HSA-2408555 https://reactome.org/PathwayBrowser/#/R-HSA-2408555 Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer TAS Homo sapiens 16144 R-HSA-8959510 https://reactome.org/PathwayBrowser/#/R-HSA-8959510 SEPHS2 phosphorylates H2Se to form SELP TAS Homo sapiens 16144 R-MMU-8959510 https://reactome.org/PathwayBrowser/#/R-MMU-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Mus musculus 16144 R-PFA-8959510 https://reactome.org/PathwayBrowser/#/R-PFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Plasmodium falciparum 16144 R-RNO-8959510 https://reactome.org/PathwayBrowser/#/R-RNO-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Rattus norvegicus 16144 R-SSC-8959510 https://reactome.org/PathwayBrowser/#/R-SSC-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Sus scrofa 16150 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 16150 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 16150 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 16150 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 16150 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 16150 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 16150 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 16150 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 16150 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 16150 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 16152 R-BTA-1675773 https://reactome.org/PathwayBrowser/#/R-BTA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Bos taurus 16152 R-BTA-1675928 https://reactome.org/PathwayBrowser/#/R-BTA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Bos taurus 16152 R-BTA-1675949 https://reactome.org/PathwayBrowser/#/R-BTA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Bos taurus 16152 R-BTA-1676109 https://reactome.org/PathwayBrowser/#/R-BTA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Bos taurus 16152 R-BTA-1676145 https://reactome.org/PathwayBrowser/#/R-BTA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Bos taurus 16152 R-BTA-1676149 https://reactome.org/PathwayBrowser/#/R-BTA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Bos taurus 16152 R-BTA-1676162 https://reactome.org/PathwayBrowser/#/R-BTA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Bos taurus 16152 R-BTA-1676164 https://reactome.org/PathwayBrowser/#/R-BTA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Bos taurus 16152 R-BTA-1676204 https://reactome.org/PathwayBrowser/#/R-BTA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Bos taurus 16152 R-BTA-1676206 https://reactome.org/PathwayBrowser/#/R-BTA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Bos taurus 16152 R-BTA-1861595 https://reactome.org/PathwayBrowser/#/R-BTA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Bos taurus 16152 R-BTA-202164 https://reactome.org/PathwayBrowser/#/R-BTA-202164 Translocation of PDK1 to Plasma membrane IEA Bos taurus 16152 R-BTA-202222 https://reactome.org/PathwayBrowser/#/R-BTA-202222 Phosphorylation of PKC theta IEA Bos taurus 16152 R-BTA-202237 https://reactome.org/PathwayBrowser/#/R-BTA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Bos taurus 16152 R-BTA-202394 https://reactome.org/PathwayBrowser/#/R-BTA-202394 Translocation of CARMA1 to Plasma membrane IEA Bos taurus 16152 R-BTA-202437 https://reactome.org/PathwayBrowser/#/R-BTA-202437 Phosphorylation of CARMA1 IEA Bos taurus 16152 R-BTA-202443 https://reactome.org/PathwayBrowser/#/R-BTA-202443 Oligomerization of CARMA1 IEA Bos taurus 16152 R-BTA-202459 https://reactome.org/PathwayBrowser/#/R-BTA-202459 Phosphorylation of Bcl10 IEA Bos taurus 16152 R-BTA-202466 https://reactome.org/PathwayBrowser/#/R-BTA-202466 Interaction of Bcl10 to CARMA1 IEA Bos taurus 16152 R-BTA-202472 https://reactome.org/PathwayBrowser/#/R-BTA-202472 Translocation of TRAF6 to CBM complex IEA Bos taurus 16152 R-BTA-202478 https://reactome.org/PathwayBrowser/#/R-BTA-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Bos taurus 16152 R-BTA-202489 https://reactome.org/PathwayBrowser/#/R-BTA-202489 Oligomerization of Bcl10 IEA Bos taurus 16152 R-BTA-202500 https://reactome.org/PathwayBrowser/#/R-BTA-202500 Activation of IKK complex IEA Bos taurus 16152 R-BTA-202510 https://reactome.org/PathwayBrowser/#/R-BTA-202510 Activation of TAK1-TAB2 complex IEA Bos taurus 16152 R-BTA-8849969 https://reactome.org/PathwayBrowser/#/R-BTA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Bos taurus 16152 R-BTA-8867754 https://reactome.org/PathwayBrowser/#/R-BTA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Bos taurus 16152 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 16152 R-BTA-8870332 https://reactome.org/PathwayBrowser/#/R-BTA-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 IEA Bos taurus 16152 R-CEL-1675773 https://reactome.org/PathwayBrowser/#/R-CEL-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Caenorhabditis elegans 16152 R-CEL-1675949 https://reactome.org/PathwayBrowser/#/R-CEL-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Caenorhabditis elegans 16152 R-CEL-1676109 https://reactome.org/PathwayBrowser/#/R-CEL-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Caenorhabditis elegans 16152 R-CEL-1676145 https://reactome.org/PathwayBrowser/#/R-CEL-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Caenorhabditis elegans 16152 R-CEL-1676149 https://reactome.org/PathwayBrowser/#/R-CEL-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Caenorhabditis elegans 16152 R-CEL-1676162 https://reactome.org/PathwayBrowser/#/R-CEL-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Caenorhabditis elegans 16152 R-CEL-1676164 https://reactome.org/PathwayBrowser/#/R-CEL-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Caenorhabditis elegans 16152 R-CEL-202164 https://reactome.org/PathwayBrowser/#/R-CEL-202164 Translocation of PDK1 to Plasma membrane IEA Caenorhabditis elegans 16152 R-CEL-202222 https://reactome.org/PathwayBrowser/#/R-CEL-202222 Phosphorylation of PKC theta IEA Caenorhabditis elegans 16152 R-CEL-8849969 https://reactome.org/PathwayBrowser/#/R-CEL-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Caenorhabditis elegans 16152 R-CEL-8868072 https://reactome.org/PathwayBrowser/#/R-CEL-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Caenorhabditis elegans 16152 R-CFA-1675773 https://reactome.org/PathwayBrowser/#/R-CFA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Canis familiaris 16152 R-CFA-1675928 https://reactome.org/PathwayBrowser/#/R-CFA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Canis familiaris 16152 R-CFA-1675949 https://reactome.org/PathwayBrowser/#/R-CFA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Canis familiaris 16152 R-CFA-1676109 https://reactome.org/PathwayBrowser/#/R-CFA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Canis familiaris 16152 R-CFA-1676145 https://reactome.org/PathwayBrowser/#/R-CFA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Canis familiaris 16152 R-CFA-1676149 https://reactome.org/PathwayBrowser/#/R-CFA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Canis familiaris 16152 R-CFA-1676162 https://reactome.org/PathwayBrowser/#/R-CFA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Canis familiaris 16152 R-CFA-1676164 https://reactome.org/PathwayBrowser/#/R-CFA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Canis familiaris 16152 R-CFA-1676204 https://reactome.org/PathwayBrowser/#/R-CFA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Canis familiaris 16152 R-CFA-1676206 https://reactome.org/PathwayBrowser/#/R-CFA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Canis familiaris 16152 R-CFA-1861595 https://reactome.org/PathwayBrowser/#/R-CFA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Canis familiaris 16152 R-CFA-202164 https://reactome.org/PathwayBrowser/#/R-CFA-202164 Translocation of PDK1 to Plasma membrane IEA Canis familiaris 16152 R-CFA-202222 https://reactome.org/PathwayBrowser/#/R-CFA-202222 Phosphorylation of PKC theta IEA Canis familiaris 16152 R-CFA-202237 https://reactome.org/PathwayBrowser/#/R-CFA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Canis familiaris 16152 R-CFA-202394 https://reactome.org/PathwayBrowser/#/R-CFA-202394 Translocation of CARMA1 to Plasma membrane IEA Canis familiaris 16152 R-CFA-202437 https://reactome.org/PathwayBrowser/#/R-CFA-202437 Phosphorylation of CARMA1 IEA Canis familiaris 16152 R-CFA-202443 https://reactome.org/PathwayBrowser/#/R-CFA-202443 Oligomerization of CARMA1 IEA Canis familiaris 16152 R-CFA-202453 https://reactome.org/PathwayBrowser/#/R-CFA-202453 Auto-ubiquitination of TRAF6 IEA Canis familiaris 16152 R-CFA-202459 https://reactome.org/PathwayBrowser/#/R-CFA-202459 Phosphorylation of Bcl10 IEA Canis familiaris 16152 R-CFA-202466 https://reactome.org/PathwayBrowser/#/R-CFA-202466 Interaction of Bcl10 to CARMA1 IEA Canis familiaris 16152 R-CFA-202472 https://reactome.org/PathwayBrowser/#/R-CFA-202472 Translocation of TRAF6 to CBM complex IEA Canis familiaris 16152 R-CFA-202478 https://reactome.org/PathwayBrowser/#/R-CFA-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Canis familiaris 16152 R-CFA-202489 https://reactome.org/PathwayBrowser/#/R-CFA-202489 Oligomerization of Bcl10 IEA Canis familiaris 16152 R-CFA-202500 https://reactome.org/PathwayBrowser/#/R-CFA-202500 Activation of IKK complex IEA Canis familiaris 16152 R-CFA-202510 https://reactome.org/PathwayBrowser/#/R-CFA-202510 Activation of TAK1-TAB2 complex IEA Canis familiaris 16152 R-CFA-202534 https://reactome.org/PathwayBrowser/#/R-CFA-202534 Ubiquitination of NEMO by TRAF6 IEA Canis familiaris 16152 R-CFA-8849969 https://reactome.org/PathwayBrowser/#/R-CFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Canis familiaris 16152 R-CFA-8867754 https://reactome.org/PathwayBrowser/#/R-CFA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Canis familiaris 16152 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 16152 R-CFA-8870332 https://reactome.org/PathwayBrowser/#/R-CFA-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 IEA Canis familiaris 16152 R-CFA-8941234 https://reactome.org/PathwayBrowser/#/R-CFA-8941234 SH3PXD2A binds ADAM12,ADAM15,ADAM19 IEA Canis familiaris 16152 R-DDI-1675773 https://reactome.org/PathwayBrowser/#/R-DDI-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Dictyostelium discoideum 16152 R-DDI-1675928 https://reactome.org/PathwayBrowser/#/R-DDI-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Dictyostelium discoideum 16152 R-DDI-1675949 https://reactome.org/PathwayBrowser/#/R-DDI-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Dictyostelium discoideum 16152 R-DDI-1676109 https://reactome.org/PathwayBrowser/#/R-DDI-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Dictyostelium discoideum 16152 R-DDI-1676145 https://reactome.org/PathwayBrowser/#/R-DDI-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Dictyostelium discoideum 16152 R-DDI-1676149 https://reactome.org/PathwayBrowser/#/R-DDI-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Dictyostelium discoideum 16152 R-DDI-1676204 https://reactome.org/PathwayBrowser/#/R-DDI-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Dictyostelium discoideum 16152 R-DDI-1676206 https://reactome.org/PathwayBrowser/#/R-DDI-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Dictyostelium discoideum 16152 R-DDI-202164 https://reactome.org/PathwayBrowser/#/R-DDI-202164 Translocation of PDK1 to Plasma membrane IEA Dictyostelium discoideum 16152 R-DDI-202222 https://reactome.org/PathwayBrowser/#/R-DDI-202222 Phosphorylation of PKC theta IEA Dictyostelium discoideum 16152 R-DDI-8849969 https://reactome.org/PathwayBrowser/#/R-DDI-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Dictyostelium discoideum 16152 R-DDI-8868072 https://reactome.org/PathwayBrowser/#/R-DDI-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Dictyostelium discoideum 16152 R-DME-1675773 https://reactome.org/PathwayBrowser/#/R-DME-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Drosophila melanogaster 16152 R-DME-1675928 https://reactome.org/PathwayBrowser/#/R-DME-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Drosophila melanogaster 16152 R-DME-1675949 https://reactome.org/PathwayBrowser/#/R-DME-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Drosophila melanogaster 16152 R-DME-1676109 https://reactome.org/PathwayBrowser/#/R-DME-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Drosophila melanogaster 16152 R-DME-1676145 https://reactome.org/PathwayBrowser/#/R-DME-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Drosophila melanogaster 16152 R-DME-1676149 https://reactome.org/PathwayBrowser/#/R-DME-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Drosophila melanogaster 16152 R-DME-1676162 https://reactome.org/PathwayBrowser/#/R-DME-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Drosophila melanogaster 16152 R-DME-1676164 https://reactome.org/PathwayBrowser/#/R-DME-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Drosophila melanogaster 16152 R-DME-1676206 https://reactome.org/PathwayBrowser/#/R-DME-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Drosophila melanogaster 16152 R-DME-202164 https://reactome.org/PathwayBrowser/#/R-DME-202164 Translocation of PDK1 to Plasma membrane IEA Drosophila melanogaster 16152 R-DME-202222 https://reactome.org/PathwayBrowser/#/R-DME-202222 Phosphorylation of PKC theta IEA Drosophila melanogaster 16152 R-DME-8849969 https://reactome.org/PathwayBrowser/#/R-DME-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Drosophila melanogaster 16152 R-DME-8867754 https://reactome.org/PathwayBrowser/#/R-DME-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Drosophila melanogaster 16152 R-DME-8868072 https://reactome.org/PathwayBrowser/#/R-DME-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Drosophila melanogaster 16152 R-DRE-1675773 https://reactome.org/PathwayBrowser/#/R-DRE-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Danio rerio 16152 R-DRE-1675949 https://reactome.org/PathwayBrowser/#/R-DRE-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Danio rerio 16152 R-DRE-1676109 https://reactome.org/PathwayBrowser/#/R-DRE-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Danio rerio 16152 R-DRE-1676145 https://reactome.org/PathwayBrowser/#/R-DRE-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Danio rerio 16152 R-DRE-1676149 https://reactome.org/PathwayBrowser/#/R-DRE-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Danio rerio 16152 R-DRE-1676162 https://reactome.org/PathwayBrowser/#/R-DRE-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Danio rerio 16152 R-DRE-1676164 https://reactome.org/PathwayBrowser/#/R-DRE-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Danio rerio 16152 R-DRE-1676204 https://reactome.org/PathwayBrowser/#/R-DRE-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Danio rerio 16152 R-DRE-202164 https://reactome.org/PathwayBrowser/#/R-DRE-202164 Translocation of PDK1 to Plasma membrane IEA Danio rerio 16152 R-DRE-8849969 https://reactome.org/PathwayBrowser/#/R-DRE-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Danio rerio 16152 R-GGA-1675773 https://reactome.org/PathwayBrowser/#/R-GGA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Gallus gallus 16152 R-GGA-1675928 https://reactome.org/PathwayBrowser/#/R-GGA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Gallus gallus 16152 R-GGA-1675949 https://reactome.org/PathwayBrowser/#/R-GGA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Gallus gallus 16152 R-GGA-1676109 https://reactome.org/PathwayBrowser/#/R-GGA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Gallus gallus 16152 R-GGA-1676145 https://reactome.org/PathwayBrowser/#/R-GGA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Gallus gallus 16152 R-GGA-1676149 https://reactome.org/PathwayBrowser/#/R-GGA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Gallus gallus 16152 R-GGA-1676162 https://reactome.org/PathwayBrowser/#/R-GGA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Gallus gallus 16152 R-GGA-1676164 https://reactome.org/PathwayBrowser/#/R-GGA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Gallus gallus 16152 R-GGA-1676204 https://reactome.org/PathwayBrowser/#/R-GGA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Gallus gallus 16152 R-GGA-1676206 https://reactome.org/PathwayBrowser/#/R-GGA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Gallus gallus 16152 R-GGA-202164 https://reactome.org/PathwayBrowser/#/R-GGA-202164 Translocation of PDK1 to Plasma membrane IEA Gallus gallus 16152 R-GGA-202237 https://reactome.org/PathwayBrowser/#/R-GGA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Gallus gallus 16152 R-GGA-202394 https://reactome.org/PathwayBrowser/#/R-GGA-202394 Translocation of CARMA1 to Plasma membrane IEA Gallus gallus 16152 R-GGA-202443 https://reactome.org/PathwayBrowser/#/R-GGA-202443 Oligomerization of CARMA1 IEA Gallus gallus 16152 R-GGA-202459 https://reactome.org/PathwayBrowser/#/R-GGA-202459 Phosphorylation of Bcl10 IEA Gallus gallus 16152 R-GGA-202466 https://reactome.org/PathwayBrowser/#/R-GGA-202466 Interaction of Bcl10 to CARMA1 IEA Gallus gallus 16152 R-GGA-202472 https://reactome.org/PathwayBrowser/#/R-GGA-202472 Translocation of TRAF6 to CBM complex IEA Gallus gallus 16152 R-GGA-202478 https://reactome.org/PathwayBrowser/#/R-GGA-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Gallus gallus 16152 R-GGA-202489 https://reactome.org/PathwayBrowser/#/R-GGA-202489 Oligomerization of Bcl10 IEA Gallus gallus 16152 R-GGA-202510 https://reactome.org/PathwayBrowser/#/R-GGA-202510 Activation of TAK1-TAB2 complex IEA Gallus gallus 16152 R-GGA-8849969 https://reactome.org/PathwayBrowser/#/R-GGA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Gallus gallus 16152 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus 16152 R-GGA-8870332 https://reactome.org/PathwayBrowser/#/R-GGA-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 IEA Gallus gallus 16152 R-GGA-8941234 https://reactome.org/PathwayBrowser/#/R-GGA-8941234 SH3PXD2A binds ADAM12,ADAM15,ADAM19 IEA Gallus gallus 16152 R-HSA-1675773 https://reactome.org/PathwayBrowser/#/R-HSA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane TAS Homo sapiens 16152 R-HSA-1675834 https://reactome.org/PathwayBrowser/#/R-HSA-1675834 PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane IEA Homo sapiens 16152 R-HSA-1675928 https://reactome.org/PathwayBrowser/#/R-HSA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane TAS Homo sapiens 16152 R-HSA-1675949 https://reactome.org/PathwayBrowser/#/R-HSA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane TAS Homo sapiens 16152 R-HSA-1676109 https://reactome.org/PathwayBrowser/#/R-HSA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane TAS Homo sapiens 16152 R-HSA-1676145 https://reactome.org/PathwayBrowser/#/R-HSA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane TAS Homo sapiens 16152 R-HSA-1676149 https://reactome.org/PathwayBrowser/#/R-HSA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane TAS Homo sapiens 16152 R-HSA-1676162 https://reactome.org/PathwayBrowser/#/R-HSA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane TAS Homo sapiens 16152 R-HSA-1676164 https://reactome.org/PathwayBrowser/#/R-HSA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane TAS Homo sapiens 16152 R-HSA-1676204 https://reactome.org/PathwayBrowser/#/R-HSA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane TAS Homo sapiens 16152 R-HSA-1676206 https://reactome.org/PathwayBrowser/#/R-HSA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane TAS Homo sapiens 16152 R-HSA-1861595 https://reactome.org/PathwayBrowser/#/R-HSA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner TAS Homo sapiens 16152 R-HSA-202164 https://reactome.org/PathwayBrowser/#/R-HSA-202164 Translocation of PDK1 to Plasma membrane TAS Homo sapiens 16152 R-HSA-202222 https://reactome.org/PathwayBrowser/#/R-HSA-202222 Phosphorylation of PKC theta TAS Homo sapiens 16152 R-HSA-202237 https://reactome.org/PathwayBrowser/#/R-HSA-202237 Hydrolysis of PIP3 to PI(3,4)P2 TAS Homo sapiens 16152 R-HSA-202394 https://reactome.org/PathwayBrowser/#/R-HSA-202394 Translocation of CARMA1 to Plasma membrane TAS Homo sapiens 16152 R-HSA-202437 https://reactome.org/PathwayBrowser/#/R-HSA-202437 Phosphorylation of CARMA1 TAS Homo sapiens 16152 R-HSA-202443 https://reactome.org/PathwayBrowser/#/R-HSA-202443 Oligomerization of CARMA1 TAS Homo sapiens 16152 R-HSA-202453 https://reactome.org/PathwayBrowser/#/R-HSA-202453 Auto-ubiquitination of TRAF6 TAS Homo sapiens 16152 R-HSA-202459 https://reactome.org/PathwayBrowser/#/R-HSA-202459 Phosphorylation of Bcl10 TAS Homo sapiens 16152 R-HSA-202466 https://reactome.org/PathwayBrowser/#/R-HSA-202466 Interaction of Bcl10 to CARMA1 TAS Homo sapiens 16152 R-HSA-202472 https://reactome.org/PathwayBrowser/#/R-HSA-202472 Translocation of TRAF6 to CBM complex TAS Homo sapiens 16152 R-HSA-202478 https://reactome.org/PathwayBrowser/#/R-HSA-202478 Interaction and oligomerization of MALT1 to Bcl10 TAS Homo sapiens 16152 R-HSA-202489 https://reactome.org/PathwayBrowser/#/R-HSA-202489 Oligomerization of Bcl10 TAS Homo sapiens 16152 R-HSA-202500 https://reactome.org/PathwayBrowser/#/R-HSA-202500 Activation of IKK complex TAS Homo sapiens 16152 R-HSA-202510 https://reactome.org/PathwayBrowser/#/R-HSA-202510 Activation of TAK1-TAB2 complex TAS Homo sapiens 16152 R-HSA-202534 https://reactome.org/PathwayBrowser/#/R-HSA-202534 Ubiquitination of NEMO by TRAF6 TAS Homo sapiens 16152 R-HSA-8849969 https://reactome.org/PathwayBrowser/#/R-HSA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane TAS Homo sapiens 16152 R-HSA-8867754 https://reactome.org/PathwayBrowser/#/R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit TAS Homo sapiens 16152 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 16152 R-HSA-8870332 https://reactome.org/PathwayBrowser/#/R-HSA-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 TAS Homo sapiens 16152 R-HSA-8941234 https://reactome.org/PathwayBrowser/#/R-HSA-8941234 SH3PXD2A binds ADAM12,ADAM15,ADAM19 TAS Homo sapiens 16152 R-MMU-1675773 https://reactome.org/PathwayBrowser/#/R-MMU-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Mus musculus 16152 R-MMU-1675928 https://reactome.org/PathwayBrowser/#/R-MMU-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Mus musculus 16152 R-MMU-1675949 https://reactome.org/PathwayBrowser/#/R-MMU-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Mus musculus 16152 R-MMU-1676109 https://reactome.org/PathwayBrowser/#/R-MMU-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Mus musculus 16152 R-MMU-1676139 https://reactome.org/PathwayBrowser/#/R-MMU-1676139 PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane TAS Mus musculus 16152 R-MMU-1676145 https://reactome.org/PathwayBrowser/#/R-MMU-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Mus musculus 16152 R-MMU-1676149 https://reactome.org/PathwayBrowser/#/R-MMU-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Mus musculus 16152 R-MMU-1676162 https://reactome.org/PathwayBrowser/#/R-MMU-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Mus musculus 16152 R-MMU-1676164 https://reactome.org/PathwayBrowser/#/R-MMU-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Mus musculus 16152 R-MMU-1676204 https://reactome.org/PathwayBrowser/#/R-MMU-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Mus musculus 16152 R-MMU-1676206 https://reactome.org/PathwayBrowser/#/R-MMU-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Mus musculus 16152 R-MMU-1861595 https://reactome.org/PathwayBrowser/#/R-MMU-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Mus musculus 16152 R-MMU-202164 https://reactome.org/PathwayBrowser/#/R-MMU-202164 Translocation of PDK1 to Plasma membrane IEA Mus musculus 16152 R-MMU-202222 https://reactome.org/PathwayBrowser/#/R-MMU-202222 Phosphorylation of PKC theta IEA Mus musculus 16152 R-MMU-202237 https://reactome.org/PathwayBrowser/#/R-MMU-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Mus musculus 16152 R-MMU-202394 https://reactome.org/PathwayBrowser/#/R-MMU-202394 Translocation of CARMA1 to Plasma membrane IEA Mus musculus 16152 R-MMU-202437 https://reactome.org/PathwayBrowser/#/R-MMU-202437 Phosphorylation of CARMA1 IEA Mus musculus 16152 R-MMU-202443 https://reactome.org/PathwayBrowser/#/R-MMU-202443 Oligomerization of CARMA1 IEA Mus musculus 16152 R-MMU-202453 https://reactome.org/PathwayBrowser/#/R-MMU-202453 Auto-ubiquitination of TRAF6 IEA Mus musculus 16152 R-MMU-202459 https://reactome.org/PathwayBrowser/#/R-MMU-202459 Phosphorylation of Bcl10 IEA Mus musculus 16152 R-MMU-202466 https://reactome.org/PathwayBrowser/#/R-MMU-202466 Interaction of Bcl10 to CARMA1 IEA Mus musculus 16152 R-MMU-202472 https://reactome.org/PathwayBrowser/#/R-MMU-202472 Translocation of TRAF6 to CBM complex IEA Mus musculus 16152 R-MMU-202478 https://reactome.org/PathwayBrowser/#/R-MMU-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Mus musculus 16152 R-MMU-202489 https://reactome.org/PathwayBrowser/#/R-MMU-202489 Oligomerization of Bcl10 IEA Mus musculus 16152 R-MMU-202500 https://reactome.org/PathwayBrowser/#/R-MMU-202500 Activation of IKK complex IEA Mus musculus 16152 R-MMU-202510 https://reactome.org/PathwayBrowser/#/R-MMU-202510 Activation of TAK1-TAB2 complex IEA Mus musculus 16152 R-MMU-202534 https://reactome.org/PathwayBrowser/#/R-MMU-202534 Ubiquitination of NEMO by TRAF6 IEA Mus musculus 16152 R-MMU-8849969 https://reactome.org/PathwayBrowser/#/R-MMU-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Mus musculus 16152 R-MMU-8867754 https://reactome.org/PathwayBrowser/#/R-MMU-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Mus musculus 16152 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 16152 R-MMU-8870332 https://reactome.org/PathwayBrowser/#/R-MMU-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 IEA Mus musculus 16152 R-MMU-8941234 https://reactome.org/PathwayBrowser/#/R-MMU-8941234 SH3PXD2A binds ADAM12,ADAM15,ADAM19 IEA Mus musculus 16152 R-PFA-1675773 https://reactome.org/PathwayBrowser/#/R-PFA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Plasmodium falciparum 16152 R-PFA-1675949 https://reactome.org/PathwayBrowser/#/R-PFA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Plasmodium falciparum 16152 R-PFA-1676145 https://reactome.org/PathwayBrowser/#/R-PFA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Plasmodium falciparum 16152 R-PFA-202164 https://reactome.org/PathwayBrowser/#/R-PFA-202164 Translocation of PDK1 to Plasma membrane IEA Plasmodium falciparum 16152 R-PFA-8849969 https://reactome.org/PathwayBrowser/#/R-PFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Plasmodium falciparum 16152 R-RNO-1675773 https://reactome.org/PathwayBrowser/#/R-RNO-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Rattus norvegicus 16152 R-RNO-1675928 https://reactome.org/PathwayBrowser/#/R-RNO-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Rattus norvegicus 16152 R-RNO-1675949 https://reactome.org/PathwayBrowser/#/R-RNO-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Rattus norvegicus 16152 R-RNO-1676109 https://reactome.org/PathwayBrowser/#/R-RNO-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Rattus norvegicus 16152 R-RNO-1676145 https://reactome.org/PathwayBrowser/#/R-RNO-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Rattus norvegicus 16152 R-RNO-1676149 https://reactome.org/PathwayBrowser/#/R-RNO-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Rattus norvegicus 16152 R-RNO-1676162 https://reactome.org/PathwayBrowser/#/R-RNO-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Rattus norvegicus 16152 R-RNO-1676164 https://reactome.org/PathwayBrowser/#/R-RNO-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Rattus norvegicus 16152 R-RNO-1676204 https://reactome.org/PathwayBrowser/#/R-RNO-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Rattus norvegicus 16152 R-RNO-1676206 https://reactome.org/PathwayBrowser/#/R-RNO-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Rattus norvegicus 16152 R-RNO-1861595 https://reactome.org/PathwayBrowser/#/R-RNO-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Rattus norvegicus 16152 R-RNO-202164 https://reactome.org/PathwayBrowser/#/R-RNO-202164 Translocation of PDK1 to Plasma membrane IEA Rattus norvegicus 16152 R-RNO-202222 https://reactome.org/PathwayBrowser/#/R-RNO-202222 Phosphorylation of PKC theta IEA Rattus norvegicus 16152 R-RNO-202237 https://reactome.org/PathwayBrowser/#/R-RNO-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Rattus norvegicus 16152 R-RNO-202394 https://reactome.org/PathwayBrowser/#/R-RNO-202394 Translocation of CARMA1 to Plasma membrane IEA Rattus norvegicus 16152 R-RNO-202437 https://reactome.org/PathwayBrowser/#/R-RNO-202437 Phosphorylation of CARMA1 IEA Rattus norvegicus 16152 R-RNO-202443 https://reactome.org/PathwayBrowser/#/R-RNO-202443 Oligomerization of CARMA1 IEA Rattus norvegicus 16152 R-RNO-202459 https://reactome.org/PathwayBrowser/#/R-RNO-202459 Phosphorylation of Bcl10 IEA Rattus norvegicus 16152 R-RNO-202466 https://reactome.org/PathwayBrowser/#/R-RNO-202466 Interaction of Bcl10 to CARMA1 IEA Rattus norvegicus 16152 R-RNO-202472 https://reactome.org/PathwayBrowser/#/R-RNO-202472 Translocation of TRAF6 to CBM complex IEA Rattus norvegicus 16152 R-RNO-202478 https://reactome.org/PathwayBrowser/#/R-RNO-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Rattus norvegicus 16152 R-RNO-202489 https://reactome.org/PathwayBrowser/#/R-RNO-202489 Oligomerization of Bcl10 IEA Rattus norvegicus 16152 R-RNO-202500 https://reactome.org/PathwayBrowser/#/R-RNO-202500 Activation of IKK complex IEA Rattus norvegicus 16152 R-RNO-202510 https://reactome.org/PathwayBrowser/#/R-RNO-202510 Activation of TAK1-TAB2 complex IEA Rattus norvegicus 16152 R-RNO-8849969 https://reactome.org/PathwayBrowser/#/R-RNO-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Rattus norvegicus 16152 R-RNO-8867754 https://reactome.org/PathwayBrowser/#/R-RNO-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Rattus norvegicus 16152 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 16152 R-RNO-8870332 https://reactome.org/PathwayBrowser/#/R-RNO-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 IEA Rattus norvegicus 16152 R-RNO-8941234 https://reactome.org/PathwayBrowser/#/R-RNO-8941234 SH3PXD2A binds ADAM12,ADAM15,ADAM19 IEA Rattus norvegicus 16152 R-SCE-1675773 https://reactome.org/PathwayBrowser/#/R-SCE-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Saccharomyces cerevisiae 16152 R-SCE-1675949 https://reactome.org/PathwayBrowser/#/R-SCE-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Saccharomyces cerevisiae 16152 R-SCE-1676145 https://reactome.org/PathwayBrowser/#/R-SCE-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Saccharomyces cerevisiae 16152 R-SCE-1676149 https://reactome.org/PathwayBrowser/#/R-SCE-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Saccharomyces cerevisiae 16152 R-SCE-1676204 https://reactome.org/PathwayBrowser/#/R-SCE-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Saccharomyces cerevisiae 16152 R-SCE-202164 https://reactome.org/PathwayBrowser/#/R-SCE-202164 Translocation of PDK1 to Plasma membrane IEA Saccharomyces cerevisiae 16152 R-SCE-202222 https://reactome.org/PathwayBrowser/#/R-SCE-202222 Phosphorylation of PKC theta IEA Saccharomyces cerevisiae 16152 R-SPO-1675773 https://reactome.org/PathwayBrowser/#/R-SPO-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Schizosaccharomyces pombe 16152 R-SPO-1676145 https://reactome.org/PathwayBrowser/#/R-SPO-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Schizosaccharomyces pombe 16152 R-SPO-1676149 https://reactome.org/PathwayBrowser/#/R-SPO-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Schizosaccharomyces pombe 16152 R-SPO-1676204 https://reactome.org/PathwayBrowser/#/R-SPO-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Schizosaccharomyces pombe 16152 R-SPO-202164 https://reactome.org/PathwayBrowser/#/R-SPO-202164 Translocation of PDK1 to Plasma membrane IEA Schizosaccharomyces pombe 16152 R-SPO-202222 https://reactome.org/PathwayBrowser/#/R-SPO-202222 Phosphorylation of PKC theta IEA Schizosaccharomyces pombe 16152 R-SPO-8941234 https://reactome.org/PathwayBrowser/#/R-SPO-8941234 SH3PXD2A binds ADAM12,ADAM15,ADAM19 IEA Schizosaccharomyces pombe 16152 R-SSC-1675773 https://reactome.org/PathwayBrowser/#/R-SSC-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Sus scrofa 16152 R-SSC-1675928 https://reactome.org/PathwayBrowser/#/R-SSC-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Sus scrofa 16152 R-SSC-1675949 https://reactome.org/PathwayBrowser/#/R-SSC-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Sus scrofa 16152 R-SSC-1676109 https://reactome.org/PathwayBrowser/#/R-SSC-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Sus scrofa 16152 R-SSC-1676145 https://reactome.org/PathwayBrowser/#/R-SSC-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Sus scrofa 16152 R-SSC-1676149 https://reactome.org/PathwayBrowser/#/R-SSC-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Sus scrofa 16152 R-SSC-1676162 https://reactome.org/PathwayBrowser/#/R-SSC-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Sus scrofa 16152 R-SSC-1676164 https://reactome.org/PathwayBrowser/#/R-SSC-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Sus scrofa 16152 R-SSC-1676204 https://reactome.org/PathwayBrowser/#/R-SSC-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Sus scrofa 16152 R-SSC-1676206 https://reactome.org/PathwayBrowser/#/R-SSC-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Sus scrofa 16152 R-SSC-1861595 https://reactome.org/PathwayBrowser/#/R-SSC-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Sus scrofa 16152 R-SSC-202164 https://reactome.org/PathwayBrowser/#/R-SSC-202164 Translocation of PDK1 to Plasma membrane IEA Sus scrofa 16152 R-SSC-202222 https://reactome.org/PathwayBrowser/#/R-SSC-202222 Phosphorylation of PKC theta IEA Sus scrofa 16152 R-SSC-202237 https://reactome.org/PathwayBrowser/#/R-SSC-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Sus scrofa 16152 R-SSC-202394 https://reactome.org/PathwayBrowser/#/R-SSC-202394 Translocation of CARMA1 to Plasma membrane IEA Sus scrofa 16152 R-SSC-202437 https://reactome.org/PathwayBrowser/#/R-SSC-202437 Phosphorylation of CARMA1 IEA Sus scrofa 16152 R-SSC-202443 https://reactome.org/PathwayBrowser/#/R-SSC-202443 Oligomerization of CARMA1 IEA Sus scrofa 16152 R-SSC-202453 https://reactome.org/PathwayBrowser/#/R-SSC-202453 Auto-ubiquitination of TRAF6 IEA Sus scrofa 16152 R-SSC-202459 https://reactome.org/PathwayBrowser/#/R-SSC-202459 Phosphorylation of Bcl10 IEA Sus scrofa 16152 R-SSC-202466 https://reactome.org/PathwayBrowser/#/R-SSC-202466 Interaction of Bcl10 to CARMA1 IEA Sus scrofa 16152 R-SSC-202472 https://reactome.org/PathwayBrowser/#/R-SSC-202472 Translocation of TRAF6 to CBM complex IEA Sus scrofa 16152 R-SSC-202478 https://reactome.org/PathwayBrowser/#/R-SSC-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Sus scrofa 16152 R-SSC-202489 https://reactome.org/PathwayBrowser/#/R-SSC-202489 Oligomerization of Bcl10 IEA Sus scrofa 16152 R-SSC-202500 https://reactome.org/PathwayBrowser/#/R-SSC-202500 Activation of IKK complex IEA Sus scrofa 16152 R-SSC-202510 https://reactome.org/PathwayBrowser/#/R-SSC-202510 Activation of TAK1-TAB2 complex IEA Sus scrofa 16152 R-SSC-202534 https://reactome.org/PathwayBrowser/#/R-SSC-202534 Ubiquitination of NEMO by TRAF6 IEA Sus scrofa 16152 R-SSC-8849969 https://reactome.org/PathwayBrowser/#/R-SSC-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Sus scrofa 16152 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa 16152 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 16152 R-SSC-8870332 https://reactome.org/PathwayBrowser/#/R-SSC-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 IEA Sus scrofa 16152 R-SSC-8941234 https://reactome.org/PathwayBrowser/#/R-SSC-8941234 SH3PXD2A binds ADAM12,ADAM15,ADAM19 IEA Sus scrofa 16152 R-XTR-1675773 https://reactome.org/PathwayBrowser/#/R-XTR-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Xenopus tropicalis 16152 R-XTR-1675928 https://reactome.org/PathwayBrowser/#/R-XTR-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Xenopus tropicalis 16152 R-XTR-1675949 https://reactome.org/PathwayBrowser/#/R-XTR-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Xenopus tropicalis 16152 R-XTR-1676109 https://reactome.org/PathwayBrowser/#/R-XTR-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Xenopus tropicalis 16152 R-XTR-1676145 https://reactome.org/PathwayBrowser/#/R-XTR-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Xenopus tropicalis 16152 R-XTR-1676149 https://reactome.org/PathwayBrowser/#/R-XTR-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Xenopus tropicalis 16152 R-XTR-1676162 https://reactome.org/PathwayBrowser/#/R-XTR-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Xenopus tropicalis 16152 R-XTR-1676164 https://reactome.org/PathwayBrowser/#/R-XTR-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Xenopus tropicalis 16152 R-XTR-1676204 https://reactome.org/PathwayBrowser/#/R-XTR-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Xenopus tropicalis 16152 R-XTR-1676206 https://reactome.org/PathwayBrowser/#/R-XTR-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Xenopus tropicalis 16152 R-XTR-202164 https://reactome.org/PathwayBrowser/#/R-XTR-202164 Translocation of PDK1 to Plasma membrane IEA Xenopus tropicalis 16152 R-XTR-202237 https://reactome.org/PathwayBrowser/#/R-XTR-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Xenopus tropicalis 16152 R-XTR-202394 https://reactome.org/PathwayBrowser/#/R-XTR-202394 Translocation of CARMA1 to Plasma membrane IEA Xenopus tropicalis 16152 R-XTR-202443 https://reactome.org/PathwayBrowser/#/R-XTR-202443 Oligomerization of CARMA1 IEA Xenopus tropicalis 16152 R-XTR-8849969 https://reactome.org/PathwayBrowser/#/R-XTR-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Xenopus tropicalis 16169 R-BTA-71163 https://reactome.org/PathwayBrowser/#/R-BTA-71163 HPD dioxygenates HPP IEA Bos taurus 16169 R-BTA-71164 https://reactome.org/PathwayBrowser/#/R-BTA-71164 HGD dioxygenates homogentisate IEA Bos taurus 16169 R-CEL-71163 https://reactome.org/PathwayBrowser/#/R-CEL-71163 HPD dioxygenates HPP IEA Caenorhabditis elegans 16169 R-CEL-71164 https://reactome.org/PathwayBrowser/#/R-CEL-71164 HGD dioxygenates homogentisate IEA Caenorhabditis elegans 16169 R-CFA-71163 https://reactome.org/PathwayBrowser/#/R-CFA-71163 HPD dioxygenates HPP IEA Canis familiaris 16169 R-CFA-71164 https://reactome.org/PathwayBrowser/#/R-CFA-71164 HGD dioxygenates homogentisate IEA Canis familiaris 16169 R-DDI-71163 https://reactome.org/PathwayBrowser/#/R-DDI-71163 HPD dioxygenates HPP IEA Dictyostelium discoideum 16169 R-DDI-71164 https://reactome.org/PathwayBrowser/#/R-DDI-71164 HGD dioxygenates homogentisate IEA Dictyostelium discoideum 16169 R-DME-71163 https://reactome.org/PathwayBrowser/#/R-DME-71163 HPD dioxygenates HPP IEA Drosophila melanogaster 16169 R-DME-71164 https://reactome.org/PathwayBrowser/#/R-DME-71164 HGD dioxygenates homogentisate IEA Drosophila melanogaster 16169 R-DRE-71163 https://reactome.org/PathwayBrowser/#/R-DRE-71163 HPD dioxygenates HPP IEA Danio rerio 16169 R-DRE-71164 https://reactome.org/PathwayBrowser/#/R-DRE-71164 HGD dioxygenates homogentisate IEA Danio rerio 16169 R-GGA-71163 https://reactome.org/PathwayBrowser/#/R-GGA-71163 HPD dioxygenates HPP IEA Gallus gallus 16169 R-GGA-71164 https://reactome.org/PathwayBrowser/#/R-GGA-71164 HGD dioxygenates homogentisate IEA Gallus gallus 16169 R-HSA-71163 https://reactome.org/PathwayBrowser/#/R-HSA-71163 HPD dioxygenates HPP TAS Homo sapiens 16169 R-HSA-71164 https://reactome.org/PathwayBrowser/#/R-HSA-71164 HGD dioxygenates homogentisate TAS Homo sapiens 16169 R-MMU-71163 https://reactome.org/PathwayBrowser/#/R-MMU-71163 HPD dioxygenates HPP IEA Mus musculus 16169 R-MMU-71164 https://reactome.org/PathwayBrowser/#/R-MMU-71164 HGD dioxygenates homogentisate IEA Mus musculus 16169 R-RNO-71163 https://reactome.org/PathwayBrowser/#/R-RNO-71163 HPD dioxygenates HPP IEA Rattus norvegicus 16169 R-RNO-71164 https://reactome.org/PathwayBrowser/#/R-RNO-71164 HGD dioxygenates homogentisate IEA Rattus norvegicus 16169 R-SSC-71163 https://reactome.org/PathwayBrowser/#/R-SSC-71163 HPD dioxygenates HPP IEA Sus scrofa 16169 R-SSC-71164 https://reactome.org/PathwayBrowser/#/R-SSC-71164 HGD dioxygenates homogentisate IEA Sus scrofa 16169 R-XTR-71163 https://reactome.org/PathwayBrowser/#/R-XTR-71163 HPD dioxygenates HPP IEA Xenopus tropicalis 16187 R-BTA-5693347 https://reactome.org/PathwayBrowser/#/R-BTA-5693347 CRYM reduces P2C to PPCA IEA Bos taurus 16187 R-CFA-5693347 https://reactome.org/PathwayBrowser/#/R-CFA-5693347 CRYM reduces P2C to PPCA IEA Canis familiaris 16187 R-DDI-5693347 https://reactome.org/PathwayBrowser/#/R-DDI-5693347 CRYM reduces P2C to PPCA IEA Dictyostelium discoideum 16187 R-DME-5693347 https://reactome.org/PathwayBrowser/#/R-DME-5693347 CRYM reduces P2C to PPCA IEA Drosophila melanogaster 16187 R-DRE-5693347 https://reactome.org/PathwayBrowser/#/R-DRE-5693347 CRYM reduces P2C to PPCA IEA Danio rerio 16187 R-GGA-5693347 https://reactome.org/PathwayBrowser/#/R-GGA-5693347 CRYM reduces P2C to PPCA IEA Gallus gallus 16187 R-HSA-5693347 https://reactome.org/PathwayBrowser/#/R-HSA-5693347 CRYM reduces P2C to PPCA TAS Homo sapiens 16187 R-MMU-5693347 https://reactome.org/PathwayBrowser/#/R-MMU-5693347 CRYM reduces P2C to PPCA IEA Mus musculus 16187 R-RNO-5693347 https://reactome.org/PathwayBrowser/#/R-RNO-5693347 CRYM reduces P2C to PPCA IEA Rattus norvegicus 16187 R-SCE-5693347 https://reactome.org/PathwayBrowser/#/R-SCE-5693347 CRYM reduces P2C to PPCA IEA Saccharomyces cerevisiae 16187 R-SPO-5693347 https://reactome.org/PathwayBrowser/#/R-SPO-5693347 CRYM reduces P2C to PPCA IEA Schizosaccharomyces pombe 16187 R-SSC-5693347 https://reactome.org/PathwayBrowser/#/R-SSC-5693347 CRYM reduces P2C to PPCA IEA Sus scrofa 16187 R-XTR-5693347 https://reactome.org/PathwayBrowser/#/R-XTR-5693347 CRYM reduces P2C to PPCA IEA Xenopus tropicalis 16189 R-BTA-1606789 https://reactome.org/PathwayBrowser/#/R-BTA-1606789 ARSB hydrolyses DS IEA Bos taurus 16189 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 16189 R-BTA-1606839 https://reactome.org/PathwayBrowser/#/R-BTA-1606839 ARSC hydrolyzes steroid sulfates IEA Bos taurus 16189 R-BTA-1614544 https://reactome.org/PathwayBrowser/#/R-BTA-1614544 Sulfite is oxidized to sulfate IEA Bos taurus 16189 R-BTA-1614546 https://reactome.org/PathwayBrowser/#/R-BTA-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Bos taurus 16189 R-BTA-1630304 https://reactome.org/PathwayBrowser/#/R-BTA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Bos taurus 16189 R-BTA-1638032 https://reactome.org/PathwayBrowser/#/R-BTA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Bos taurus 16189 R-BTA-1678650 https://reactome.org/PathwayBrowser/#/R-BTA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Bos taurus 16189 R-BTA-1678708 https://reactome.org/PathwayBrowser/#/R-BTA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Bos taurus 16189 R-BTA-174392 https://reactome.org/PathwayBrowser/#/R-BTA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Bos taurus 16189 R-BTA-1793182 https://reactome.org/PathwayBrowser/#/R-BTA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Bos taurus 16189 R-BTA-1793207 https://reactome.org/PathwayBrowser/#/R-BTA-1793207 ARSB hydrolyses C4S/C6S chains IEA Bos taurus 16189 R-BTA-2090043 https://reactome.org/PathwayBrowser/#/R-BTA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Bos taurus 16189 R-BTA-427555 https://reactome.org/PathwayBrowser/#/R-BTA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Bos taurus 16189 R-BTA-433099 https://reactome.org/PathwayBrowser/#/R-BTA-433099 NaS2 co-transports sulphate and two sodium ions IEA Bos taurus 16189 R-BTA-433114 https://reactome.org/PathwayBrowser/#/R-BTA-433114 NaS1 co-transports sulphate and a sodium ion IEA Bos taurus 16189 R-BTA-8875871 https://reactome.org/PathwayBrowser/#/R-BTA-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Bos taurus 16189 R-BTA-9840949 https://reactome.org/PathwayBrowser/#/R-BTA-9840949 ARSA removes sulfate from SM3 IEA Bos taurus 16189 R-CEL-1606789 https://reactome.org/PathwayBrowser/#/R-CEL-1606789 ARSB hydrolyses DS IEA Caenorhabditis elegans 16189 R-CEL-1614544 https://reactome.org/PathwayBrowser/#/R-CEL-1614544 Sulfite is oxidized to sulfate IEA Caenorhabditis elegans 16189 R-CEL-1614546 https://reactome.org/PathwayBrowser/#/R-CEL-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Caenorhabditis elegans 16189 R-CEL-174392 https://reactome.org/PathwayBrowser/#/R-CEL-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Caenorhabditis elegans 16189 R-CEL-1793207 https://reactome.org/PathwayBrowser/#/R-CEL-1793207 ARSB hydrolyses C4S/C6S chains IEA Caenorhabditis elegans 16189 R-CEL-427555 https://reactome.org/PathwayBrowser/#/R-CEL-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Caenorhabditis elegans 16189 R-CEL-433099 https://reactome.org/PathwayBrowser/#/R-CEL-433099 NaS2 co-transports sulphate and two sodium ions IEA Caenorhabditis elegans 16189 R-CEL-433114 https://reactome.org/PathwayBrowser/#/R-CEL-433114 NaS1 co-transports sulphate and a sodium ion IEA Caenorhabditis elegans 16189 R-CFA-1606789 https://reactome.org/PathwayBrowser/#/R-CFA-1606789 ARSB hydrolyses DS IEA Canis familiaris 16189 R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 16189 R-CFA-1606839 https://reactome.org/PathwayBrowser/#/R-CFA-1606839 ARSC hydrolyzes steroid sulfates IEA Canis familiaris 16189 R-CFA-1614544 https://reactome.org/PathwayBrowser/#/R-CFA-1614544 Sulfite is oxidized to sulfate IEA Canis familiaris 16189 R-CFA-1614546 https://reactome.org/PathwayBrowser/#/R-CFA-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Canis familiaris 16189 R-CFA-1630304 https://reactome.org/PathwayBrowser/#/R-CFA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Canis familiaris 16189 R-CFA-1638032 https://reactome.org/PathwayBrowser/#/R-CFA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Canis familiaris 16189 R-CFA-1678650 https://reactome.org/PathwayBrowser/#/R-CFA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Canis familiaris 16189 R-CFA-1678708 https://reactome.org/PathwayBrowser/#/R-CFA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Canis familiaris 16189 R-CFA-174392 https://reactome.org/PathwayBrowser/#/R-CFA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Canis familiaris 16189 R-CFA-1793182 https://reactome.org/PathwayBrowser/#/R-CFA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Canis familiaris 16189 R-CFA-1793207 https://reactome.org/PathwayBrowser/#/R-CFA-1793207 ARSB hydrolyses C4S/C6S chains IEA Canis familiaris 16189 R-CFA-2090043 https://reactome.org/PathwayBrowser/#/R-CFA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Canis familiaris 16189 R-CFA-427555 https://reactome.org/PathwayBrowser/#/R-CFA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Canis familiaris 16189 R-CFA-433099 https://reactome.org/PathwayBrowser/#/R-CFA-433099 NaS2 co-transports sulphate and two sodium ions IEA Canis familiaris 16189 R-CFA-433114 https://reactome.org/PathwayBrowser/#/R-CFA-433114 NaS1 co-transports sulphate and a sodium ion IEA Canis familiaris 16189 R-CFA-8875871 https://reactome.org/PathwayBrowser/#/R-CFA-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Canis familiaris 16189 R-CFA-9840949 https://reactome.org/PathwayBrowser/#/R-CFA-9840949 ARSA removes sulfate from SM3 IEA Canis familiaris 16189 R-DDI-1614544 https://reactome.org/PathwayBrowser/#/R-DDI-1614544 Sulfite is oxidized to sulfate IEA Dictyostelium discoideum 16189 R-DDI-1614546 https://reactome.org/PathwayBrowser/#/R-DDI-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Dictyostelium discoideum 16189 R-DDI-427555 https://reactome.org/PathwayBrowser/#/R-DDI-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Dictyostelium discoideum 16189 R-DDI-8875871 https://reactome.org/PathwayBrowser/#/R-DDI-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Dictyostelium discoideum 16189 R-DME-1614544 https://reactome.org/PathwayBrowser/#/R-DME-1614544 Sulfite is oxidized to sulfate IEA Drosophila melanogaster 16189 R-DME-1614546 https://reactome.org/PathwayBrowser/#/R-DME-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Drosophila melanogaster 16189 R-DME-1638032 https://reactome.org/PathwayBrowser/#/R-DME-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Drosophila melanogaster 16189 R-DME-1678650 https://reactome.org/PathwayBrowser/#/R-DME-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Drosophila melanogaster 16189 R-DME-1678708 https://reactome.org/PathwayBrowser/#/R-DME-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Drosophila melanogaster 16189 R-DME-174392 https://reactome.org/PathwayBrowser/#/R-DME-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Drosophila melanogaster 16189 R-DME-1793182 https://reactome.org/PathwayBrowser/#/R-DME-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Drosophila melanogaster 16189 R-DME-2090043 https://reactome.org/PathwayBrowser/#/R-DME-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Drosophila melanogaster 16189 R-DME-427555 https://reactome.org/PathwayBrowser/#/R-DME-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Drosophila melanogaster 16189 R-DME-433099 https://reactome.org/PathwayBrowser/#/R-DME-433099 NaS2 co-transports sulphate and two sodium ions IEA Drosophila melanogaster 16189 R-DME-433114 https://reactome.org/PathwayBrowser/#/R-DME-433114 NaS1 co-transports sulphate and a sodium ion IEA Drosophila melanogaster 16189 R-DME-8875871 https://reactome.org/PathwayBrowser/#/R-DME-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Drosophila melanogaster 16189 R-DRE-1614546 https://reactome.org/PathwayBrowser/#/R-DRE-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Danio rerio 16189 R-DRE-1638032 https://reactome.org/PathwayBrowser/#/R-DRE-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Danio rerio 16189 R-DRE-1678650 https://reactome.org/PathwayBrowser/#/R-DRE-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Danio rerio 16189 R-DRE-174392 https://reactome.org/PathwayBrowser/#/R-DRE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Danio rerio 16189 R-DRE-1793182 https://reactome.org/PathwayBrowser/#/R-DRE-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Danio rerio 16189 R-DRE-427555 https://reactome.org/PathwayBrowser/#/R-DRE-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Danio rerio 16189 R-DRE-433114 https://reactome.org/PathwayBrowser/#/R-DRE-433114 NaS1 co-transports sulphate and a sodium ion IEA Danio rerio 16189 R-DRE-8875871 https://reactome.org/PathwayBrowser/#/R-DRE-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Danio rerio 16189 R-GGA-1606789 https://reactome.org/PathwayBrowser/#/R-GGA-1606789 ARSB hydrolyses DS IEA Gallus gallus 16189 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 16189 R-GGA-1606839 https://reactome.org/PathwayBrowser/#/R-GGA-1606839 ARSC hydrolyzes steroid sulfates IEA Gallus gallus 16189 R-GGA-1614544 https://reactome.org/PathwayBrowser/#/R-GGA-1614544 Sulfite is oxidized to sulfate IEA Gallus gallus 16189 R-GGA-1614546 https://reactome.org/PathwayBrowser/#/R-GGA-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Gallus gallus 16189 R-GGA-1630304 https://reactome.org/PathwayBrowser/#/R-GGA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Gallus gallus 16189 R-GGA-1638032 https://reactome.org/PathwayBrowser/#/R-GGA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Gallus gallus 16189 R-GGA-1678650 https://reactome.org/PathwayBrowser/#/R-GGA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Gallus gallus 16189 R-GGA-1678708 https://reactome.org/PathwayBrowser/#/R-GGA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Gallus gallus 16189 R-GGA-174392 https://reactome.org/PathwayBrowser/#/R-GGA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Gallus gallus 16189 R-GGA-1793182 https://reactome.org/PathwayBrowser/#/R-GGA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Gallus gallus 16189 R-GGA-1793207 https://reactome.org/PathwayBrowser/#/R-GGA-1793207 ARSB hydrolyses C4S/C6S chains IEA Gallus gallus 16189 R-GGA-2090043 https://reactome.org/PathwayBrowser/#/R-GGA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Gallus gallus 16189 R-GGA-427555 https://reactome.org/PathwayBrowser/#/R-GGA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Gallus gallus 16189 R-GGA-433099 https://reactome.org/PathwayBrowser/#/R-GGA-433099 NaS2 co-transports sulphate and two sodium ions IEA Gallus gallus 16189 R-GGA-433114 https://reactome.org/PathwayBrowser/#/R-GGA-433114 NaS1 co-transports sulphate and a sodium ion IEA Gallus gallus 16189 R-GGA-8875871 https://reactome.org/PathwayBrowser/#/R-GGA-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Gallus gallus 16189 R-GGA-9840949 https://reactome.org/PathwayBrowser/#/R-GGA-9840949 ARSA removes sulfate from SM3 IEA Gallus gallus 16189 R-HSA-1606789 https://reactome.org/PathwayBrowser/#/R-HSA-1606789 ARSB hydrolyses DS TAS Homo sapiens 16189 R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 16189 R-HSA-1606839 https://reactome.org/PathwayBrowser/#/R-HSA-1606839 ARSC hydrolyzes steroid sulfates TAS Homo sapiens 16189 R-HSA-1614544 https://reactome.org/PathwayBrowser/#/R-HSA-1614544 Sulfite is oxidized to sulfate TAS Homo sapiens 16189 R-HSA-1614546 https://reactome.org/PathwayBrowser/#/R-HSA-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate TAS Homo sapiens 16189 R-HSA-1630304 https://reactome.org/PathwayBrowser/#/R-HSA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate TAS Homo sapiens 16189 R-HSA-1638032 https://reactome.org/PathwayBrowser/#/R-HSA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate TAS Homo sapiens 16189 R-HSA-1678650 https://reactome.org/PathwayBrowser/#/R-HSA-1678650 IDS hydrolyses Heparan sulfate chain(5) TAS Homo sapiens 16189 R-HSA-1678708 https://reactome.org/PathwayBrowser/#/R-HSA-1678708 SGSH hydrolyses Heparan sulfate chain(2) TAS Homo sapiens 16189 R-HSA-174392 https://reactome.org/PathwayBrowser/#/R-HSA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS TAS Homo sapiens 16189 R-HSA-1793182 https://reactome.org/PathwayBrowser/#/R-HSA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) TAS Homo sapiens 16189 R-HSA-1793207 https://reactome.org/PathwayBrowser/#/R-HSA-1793207 ARSB hydrolyses C4S/C6S chains TAS Homo sapiens 16189 R-HSA-2090043 https://reactome.org/PathwayBrowser/#/R-HSA-2090043 SGSH hydrolyses Heparan sulfate chain(7) TAS Homo sapiens 16189 R-HSA-3560789 https://reactome.org/PathwayBrowser/#/R-HSA-3560789 Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol TAS Homo sapiens 16189 R-HSA-3560794 https://reactome.org/PathwayBrowser/#/R-HSA-3560794 Defective PAPSS2 does not transfer SO4(2-) group to ATP to form APS TAS Homo sapiens 16189 R-HSA-427555 https://reactome.org/PathwayBrowser/#/R-HSA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol TAS Homo sapiens 16189 R-HSA-433099 https://reactome.org/PathwayBrowser/#/R-HSA-433099 NaS2 co-transports sulphate and two sodium ions TAS Homo sapiens 16189 R-HSA-433114 https://reactome.org/PathwayBrowser/#/R-HSA-433114 NaS1 co-transports sulphate and a sodium ion TAS Homo sapiens 16189 R-HSA-8875871 https://reactome.org/PathwayBrowser/#/R-HSA-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol TAS Homo sapiens 16189 R-HSA-9840949 https://reactome.org/PathwayBrowser/#/R-HSA-9840949 ARSA removes sulfate from SM3 TAS Homo sapiens 16189 R-MMU-1606789 https://reactome.org/PathwayBrowser/#/R-MMU-1606789 ARSB hydrolyses DS IEA Mus musculus 16189 R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 16189 R-MMU-1606839 https://reactome.org/PathwayBrowser/#/R-MMU-1606839 ARSC hydrolyzes steroid sulfates IEA Mus musculus 16189 R-MMU-1614544 https://reactome.org/PathwayBrowser/#/R-MMU-1614544 Sulfite is oxidized to sulfate IEA Mus musculus 16189 R-MMU-1614546 https://reactome.org/PathwayBrowser/#/R-MMU-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Mus musculus 16189 R-MMU-1630304 https://reactome.org/PathwayBrowser/#/R-MMU-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Mus musculus 16189 R-MMU-1638032 https://reactome.org/PathwayBrowser/#/R-MMU-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Mus musculus 16189 R-MMU-1678650 https://reactome.org/PathwayBrowser/#/R-MMU-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Mus musculus 16189 R-MMU-1678708 https://reactome.org/PathwayBrowser/#/R-MMU-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Mus musculus 16189 R-MMU-174392 https://reactome.org/PathwayBrowser/#/R-MMU-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Mus musculus 16189 R-MMU-1793182 https://reactome.org/PathwayBrowser/#/R-MMU-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Mus musculus 16189 R-MMU-1793207 https://reactome.org/PathwayBrowser/#/R-MMU-1793207 ARSB hydrolyses C4S/C6S chains IEA Mus musculus 16189 R-MMU-2090043 https://reactome.org/PathwayBrowser/#/R-MMU-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Mus musculus 16189 R-MMU-427555 https://reactome.org/PathwayBrowser/#/R-MMU-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Mus musculus 16189 R-MMU-433099 https://reactome.org/PathwayBrowser/#/R-MMU-433099 NaS2 co-transports sulphate and two sodium ions IEA Mus musculus 16189 R-MMU-433114 https://reactome.org/PathwayBrowser/#/R-MMU-433114 NaS1 co-transports sulphate and a sodium ion IEA Mus musculus 16189 R-MMU-8875871 https://reactome.org/PathwayBrowser/#/R-MMU-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Mus musculus 16189 R-MMU-9840949 https://reactome.org/PathwayBrowser/#/R-MMU-9840949 ARSA removes sulfate from SM3 IEA Mus musculus 16189 R-MTU-936631 https://reactome.org/PathwayBrowser/#/R-MTU-936631 sulfate uptake in the cytosol TAS Mycobacterium tuberculosis 16189 R-MTU-936667 https://reactome.org/PathwayBrowser/#/R-MTU-936667 sulfate binds to SubI outside the membrane TAS Mycobacterium tuberculosis 16189 R-MTU-936729 https://reactome.org/PathwayBrowser/#/R-MTU-936729 sulfate is activated to APS TAS Mycobacterium tuberculosis 16189 R-RNO-1606789 https://reactome.org/PathwayBrowser/#/R-RNO-1606789 ARSB hydrolyses DS IEA Rattus norvegicus 16189 R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 16189 R-RNO-1606839 https://reactome.org/PathwayBrowser/#/R-RNO-1606839 ARSC hydrolyzes steroid sulfates IEA Rattus norvegicus 16189 R-RNO-1614544 https://reactome.org/PathwayBrowser/#/R-RNO-1614544 Sulfite is oxidized to sulfate IEA Rattus norvegicus 16189 R-RNO-1614546 https://reactome.org/PathwayBrowser/#/R-RNO-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Rattus norvegicus 16189 R-RNO-1630304 https://reactome.org/PathwayBrowser/#/R-RNO-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Rattus norvegicus 16189 R-RNO-1638032 https://reactome.org/PathwayBrowser/#/R-RNO-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Rattus norvegicus 16189 R-RNO-1678650 https://reactome.org/PathwayBrowser/#/R-RNO-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Rattus norvegicus 16189 R-RNO-1678708 https://reactome.org/PathwayBrowser/#/R-RNO-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Rattus norvegicus 16189 R-RNO-174392 https://reactome.org/PathwayBrowser/#/R-RNO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Rattus norvegicus 16189 R-RNO-1793182 https://reactome.org/PathwayBrowser/#/R-RNO-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Rattus norvegicus 16189 R-RNO-1793207 https://reactome.org/PathwayBrowser/#/R-RNO-1793207 ARSB hydrolyses C4S/C6S chains IEA Rattus norvegicus 16189 R-RNO-2090043 https://reactome.org/PathwayBrowser/#/R-RNO-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Rattus norvegicus 16189 R-RNO-427555 https://reactome.org/PathwayBrowser/#/R-RNO-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Rattus norvegicus 16189 R-RNO-433099 https://reactome.org/PathwayBrowser/#/R-RNO-433099 NaS2 co-transports sulphate and two sodium ions IEA Rattus norvegicus 16189 R-RNO-433114 https://reactome.org/PathwayBrowser/#/R-RNO-433114 NaS1 co-transports sulphate and a sodium ion IEA Rattus norvegicus 16189 R-RNO-8875871 https://reactome.org/PathwayBrowser/#/R-RNO-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Rattus norvegicus 16189 R-RNO-9840949 https://reactome.org/PathwayBrowser/#/R-RNO-9840949 ARSA removes sulfate from SM3 IEA Rattus norvegicus 16189 R-SCE-1614546 https://reactome.org/PathwayBrowser/#/R-SCE-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Saccharomyces cerevisiae 16189 R-SCE-174392 https://reactome.org/PathwayBrowser/#/R-SCE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Saccharomyces cerevisiae 16189 R-SCE-427555 https://reactome.org/PathwayBrowser/#/R-SCE-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 16189 R-SCE-8875871 https://reactome.org/PathwayBrowser/#/R-SCE-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Saccharomyces cerevisiae 16189 R-SPO-1606839 https://reactome.org/PathwayBrowser/#/R-SPO-1606839 ARSC hydrolyzes steroid sulfates IEA Schizosaccharomyces pombe 16189 R-SPO-1630304 https://reactome.org/PathwayBrowser/#/R-SPO-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Schizosaccharomyces pombe 16189 R-SPO-174392 https://reactome.org/PathwayBrowser/#/R-SPO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Schizosaccharomyces pombe 16189 R-SPO-427555 https://reactome.org/PathwayBrowser/#/R-SPO-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Schizosaccharomyces pombe 16189 R-SPO-8875871 https://reactome.org/PathwayBrowser/#/R-SPO-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Schizosaccharomyces pombe 16189 R-SPO-9840949 https://reactome.org/PathwayBrowser/#/R-SPO-9840949 ARSA removes sulfate from SM3 IEA Schizosaccharomyces pombe 16189 R-SSC-1606789 https://reactome.org/PathwayBrowser/#/R-SSC-1606789 ARSB hydrolyses DS IEA Sus scrofa 16189 R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 16189 R-SSC-1606839 https://reactome.org/PathwayBrowser/#/R-SSC-1606839 ARSC hydrolyzes steroid sulfates IEA Sus scrofa 16189 R-SSC-1614544 https://reactome.org/PathwayBrowser/#/R-SSC-1614544 Sulfite is oxidized to sulfate IEA Sus scrofa 16189 R-SSC-1614546 https://reactome.org/PathwayBrowser/#/R-SSC-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Sus scrofa 16189 R-SSC-1630304 https://reactome.org/PathwayBrowser/#/R-SSC-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Sus scrofa 16189 R-SSC-1638032 https://reactome.org/PathwayBrowser/#/R-SSC-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Sus scrofa 16189 R-SSC-1678650 https://reactome.org/PathwayBrowser/#/R-SSC-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Sus scrofa 16189 R-SSC-1678708 https://reactome.org/PathwayBrowser/#/R-SSC-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Sus scrofa 16189 R-SSC-174392 https://reactome.org/PathwayBrowser/#/R-SSC-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Sus scrofa 16189 R-SSC-1793182 https://reactome.org/PathwayBrowser/#/R-SSC-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Sus scrofa 16189 R-SSC-1793207 https://reactome.org/PathwayBrowser/#/R-SSC-1793207 ARSB hydrolyses C4S/C6S chains IEA Sus scrofa 16189 R-SSC-2090043 https://reactome.org/PathwayBrowser/#/R-SSC-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Sus scrofa 16189 R-SSC-427555 https://reactome.org/PathwayBrowser/#/R-SSC-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Sus scrofa 16189 R-SSC-433099 https://reactome.org/PathwayBrowser/#/R-SSC-433099 NaS2 co-transports sulphate and two sodium ions IEA Sus scrofa 16189 R-SSC-433114 https://reactome.org/PathwayBrowser/#/R-SSC-433114 NaS1 co-transports sulphate and a sodium ion IEA Sus scrofa 16189 R-SSC-8875871 https://reactome.org/PathwayBrowser/#/R-SSC-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Sus scrofa 16189 R-SSC-9840949 https://reactome.org/PathwayBrowser/#/R-SSC-9840949 ARSA removes sulfate from SM3 IEA Sus scrofa 16189 R-XTR-1606839 https://reactome.org/PathwayBrowser/#/R-XTR-1606839 ARSC hydrolyzes steroid sulfates IEA Xenopus tropicalis 16189 R-XTR-1614544 https://reactome.org/PathwayBrowser/#/R-XTR-1614544 Sulfite is oxidized to sulfate IEA Xenopus tropicalis 16189 R-XTR-1630304 https://reactome.org/PathwayBrowser/#/R-XTR-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Xenopus tropicalis 16189 R-XTR-1638032 https://reactome.org/PathwayBrowser/#/R-XTR-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Xenopus tropicalis 16189 R-XTR-1678650 https://reactome.org/PathwayBrowser/#/R-XTR-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Xenopus tropicalis 16189 R-XTR-1678708 https://reactome.org/PathwayBrowser/#/R-XTR-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Xenopus tropicalis 16189 R-XTR-174392 https://reactome.org/PathwayBrowser/#/R-XTR-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Xenopus tropicalis 16189 R-XTR-1793182 https://reactome.org/PathwayBrowser/#/R-XTR-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Xenopus tropicalis 16189 R-XTR-2090043 https://reactome.org/PathwayBrowser/#/R-XTR-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Xenopus tropicalis 16189 R-XTR-427555 https://reactome.org/PathwayBrowser/#/R-XTR-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Xenopus tropicalis 16189 R-XTR-433114 https://reactome.org/PathwayBrowser/#/R-XTR-433114 NaS1 co-transports sulphate and a sodium ion IEA Xenopus tropicalis 16189 R-XTR-8875871 https://reactome.org/PathwayBrowser/#/R-XTR-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Xenopus tropicalis 16189 R-XTR-9840949 https://reactome.org/PathwayBrowser/#/R-XTR-9840949 ARSA removes sulfate from SM3 IEA Xenopus tropicalis 16196 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 16196 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 16196 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 16196 R-BTA-400434 https://reactome.org/PathwayBrowser/#/R-BTA-400434 FFAR1 binds fatty acids IEA Bos taurus 16196 R-BTA-400509 https://reactome.org/PathwayBrowser/#/R-BTA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Bos taurus 16196 R-BTA-416530 https://reactome.org/PathwayBrowser/#/R-BTA-416530 FFAR1:FFAR1 ligands activate Gq IEA Bos taurus 16196 R-BTA-444202 https://reactome.org/PathwayBrowser/#/R-BTA-444202 Receptor FFAR1 binds free fatty acids IEA Bos taurus 16196 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 16196 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 16196 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 16196 R-BTA-879585 https://reactome.org/PathwayBrowser/#/R-BTA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Bos taurus 16196 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 16196 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 16196 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 16196 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 16196 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 16196 R-CEL-879585 https://reactome.org/PathwayBrowser/#/R-CEL-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Caenorhabditis elegans 16196 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 16196 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 16196 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 16196 R-CFA-400434 https://reactome.org/PathwayBrowser/#/R-CFA-400434 FFAR1 binds fatty acids IEA Canis familiaris 16196 R-CFA-400509 https://reactome.org/PathwayBrowser/#/R-CFA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Canis familiaris 16196 R-CFA-416530 https://reactome.org/PathwayBrowser/#/R-CFA-416530 FFAR1:FFAR1 ligands activate Gq IEA Canis familiaris 16196 R-CFA-444202 https://reactome.org/PathwayBrowser/#/R-CFA-444202 Receptor FFAR1 binds free fatty acids IEA Canis familiaris 16196 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 16196 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 16196 R-CFA-879585 https://reactome.org/PathwayBrowser/#/R-CFA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Canis familiaris 16196 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 16196 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 16196 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 16196 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 16196 R-DME-879585 https://reactome.org/PathwayBrowser/#/R-DME-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Drosophila melanogaster 16196 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 16196 R-DRE-879585 https://reactome.org/PathwayBrowser/#/R-DRE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Danio rerio 16196 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 16196 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 16196 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 16196 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 16196 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 16196 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 16196 R-GGA-879585 https://reactome.org/PathwayBrowser/#/R-GGA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Gallus gallus 16196 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 16196 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 16196 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 16196 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 16196 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 16196 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 16196 R-HSA-400434 https://reactome.org/PathwayBrowser/#/R-HSA-400434 FFAR1 binds fatty acids TAS Homo sapiens 16196 R-HSA-400509 https://reactome.org/PathwayBrowser/#/R-HSA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells TAS Homo sapiens 16196 R-HSA-416530 https://reactome.org/PathwayBrowser/#/R-HSA-416530 FFAR1:FFAR1 ligands activate Gq TAS Homo sapiens 16196 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 16196 R-HSA-444202 https://reactome.org/PathwayBrowser/#/R-HSA-444202 Receptor FFAR1 binds free fatty acids TAS Homo sapiens 16196 R-HSA-5627891 https://reactome.org/PathwayBrowser/#/R-HSA-5627891 Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol TAS Homo sapiens 16196 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 16196 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 16196 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 16196 R-HSA-879585 https://reactome.org/PathwayBrowser/#/R-HSA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol TAS Homo sapiens 16196 R-HSA-9844415 https://reactome.org/PathwayBrowser/#/R-HSA-9844415 PRDM16 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 IEA Homo sapiens 16196 R-HSA-9844440 https://reactome.org/PathwayBrowser/#/R-HSA-9844440 PPARG binds EBF2-bound gene loci IEA Homo sapiens 16196 R-HSA-9844536 https://reactome.org/PathwayBrowser/#/R-HSA-9844536 PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 16196 R-HSA-9844549 https://reactome.org/PathwayBrowser/#/R-HSA-9844549 UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 16196 R-HSA-9844600 https://reactome.org/PathwayBrowser/#/R-HSA-9844600 CIDEA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 16196 R-HSA-9844822 https://reactome.org/PathwayBrowser/#/R-HSA-9844822 PPARGC1A gene expression is stimulated by EBF2 IEA Homo sapiens 16196 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 16196 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 16196 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 16196 R-MMU-400434 https://reactome.org/PathwayBrowser/#/R-MMU-400434 FFAR1 binds fatty acids IEA Mus musculus 16196 R-MMU-400509 https://reactome.org/PathwayBrowser/#/R-MMU-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Mus musculus 16196 R-MMU-416530 https://reactome.org/PathwayBrowser/#/R-MMU-416530 FFAR1:FFAR1 ligands activate Gq IEA Mus musculus 16196 R-MMU-444202 https://reactome.org/PathwayBrowser/#/R-MMU-444202 Receptor FFAR1 binds free fatty acids IEA Mus musculus 16196 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 16196 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 16196 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 16196 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 16196 R-MMU-879585 https://reactome.org/PathwayBrowser/#/R-MMU-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Mus musculus 16196 R-MMU-9844541 https://reactome.org/PathwayBrowser/#/R-MMU-9844541 Ppara gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 16196 R-MMU-9844554 https://reactome.org/PathwayBrowser/#/R-MMU-9844554 Ucp1 gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 16196 R-MMU-9844626 https://reactome.org/PathwayBrowser/#/R-MMU-9844626 Cidea gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 16196 R-MMU-9844655 https://reactome.org/PathwayBrowser/#/R-MMU-9844655 Dio2 gene expression is stimulated by Ebf2 and repressed by Znf423 and NuRD TAS Mus musculus 16196 R-MMU-9844700 https://reactome.org/PathwayBrowser/#/R-MMU-9844700 Pparg binds Ebf2-bound gene loci TAS Mus musculus 16196 R-MMU-9844775 https://reactome.org/PathwayBrowser/#/R-MMU-9844775 Prdm16 gene expression is stimulated by Ebf2 and Pparg and inhibited by Znf423 TAS Mus musculus 16196 R-MMU-9844841 https://reactome.org/PathwayBrowser/#/R-MMU-9844841 Ppargc1a gene expression is positively regulated by Ebf2 and Pparg TAS Mus musculus 16196 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 16196 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 16196 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 16196 R-RNO-400434 https://reactome.org/PathwayBrowser/#/R-RNO-400434 FFAR1 binds fatty acids IEA Rattus norvegicus 16196 R-RNO-400509 https://reactome.org/PathwayBrowser/#/R-RNO-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Rattus norvegicus 16196 R-RNO-416530 https://reactome.org/PathwayBrowser/#/R-RNO-416530 FFAR1:FFAR1 ligands activate Gq IEA Rattus norvegicus 16196 R-RNO-444202 https://reactome.org/PathwayBrowser/#/R-RNO-444202 Receptor FFAR1 binds free fatty acids IEA Rattus norvegicus 16196 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 16196 R-RNO-879585 https://reactome.org/PathwayBrowser/#/R-RNO-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Rattus norvegicus 16196 R-SCE-879585 https://reactome.org/PathwayBrowser/#/R-SCE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Saccharomyces cerevisiae 16196 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 16196 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 16196 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 16196 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 16196 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 16196 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 16196 R-SSC-879585 https://reactome.org/PathwayBrowser/#/R-SSC-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Sus scrofa 16196 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 16196 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 16196 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 16196 R-XTR-879585 https://reactome.org/PathwayBrowser/#/R-XTR-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Xenopus tropicalis 16197 R-BTA-1638845 https://reactome.org/PathwayBrowser/#/R-BTA-1638845 CERK phosphorylates CERA to form C1P IEA Bos taurus 16197 R-BTA-5339535 https://reactome.org/PathwayBrowser/#/R-BTA-5339535 CPTP transports C1P from plasma membrane to Golgi membrane IEA Bos taurus 16197 R-CEL-1638845 https://reactome.org/PathwayBrowser/#/R-CEL-1638845 CERK phosphorylates CERA to form C1P IEA Caenorhabditis elegans 16197 R-CEL-5339535 https://reactome.org/PathwayBrowser/#/R-CEL-5339535 CPTP transports C1P from plasma membrane to Golgi membrane IEA Caenorhabditis elegans 16197 R-CFA-1638845 https://reactome.org/PathwayBrowser/#/R-CFA-1638845 CERK phosphorylates CERA to form C1P IEA Canis familiaris 16197 R-CFA-5339535 https://reactome.org/PathwayBrowser/#/R-CFA-5339535 CPTP transports C1P from plasma membrane to Golgi membrane IEA Canis familiaris 16197 R-DME-1638845 https://reactome.org/PathwayBrowser/#/R-DME-1638845 CERK phosphorylates CERA to form C1P IEA Drosophila melanogaster 16197 R-DME-5339535 https://reactome.org/PathwayBrowser/#/R-DME-5339535 CPTP transports C1P from plasma membrane to Golgi membrane IEA Drosophila melanogaster 16197 R-DRE-5339535 https://reactome.org/PathwayBrowser/#/R-DRE-5339535 CPTP transports C1P from plasma membrane to Golgi membrane IEA Danio rerio 16197 R-GGA-1638845 https://reactome.org/PathwayBrowser/#/R-GGA-1638845 CERK phosphorylates CERA to form C1P IEA Gallus gallus 16197 R-HSA-1638845 https://reactome.org/PathwayBrowser/#/R-HSA-1638845 CERK phosphorylates CERA to form C1P TAS Homo sapiens 16197 R-HSA-5339535 https://reactome.org/PathwayBrowser/#/R-HSA-5339535 CPTP transports C1P from plasma membrane to Golgi membrane TAS Homo sapiens 16197 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 16197 R-MMU-1638845 https://reactome.org/PathwayBrowser/#/R-MMU-1638845 CERK phosphorylates CERA to form C1P IEA Mus musculus 16197 R-MMU-5339535 https://reactome.org/PathwayBrowser/#/R-MMU-5339535 CPTP transports C1P from plasma membrane to Golgi membrane IEA Mus musculus 16197 R-PFA-5339535 https://reactome.org/PathwayBrowser/#/R-PFA-5339535 CPTP transports C1P from plasma membrane to Golgi membrane IEA Plasmodium falciparum 16197 R-RNO-1638845 https://reactome.org/PathwayBrowser/#/R-RNO-1638845 CERK phosphorylates CERA to form C1P IEA Rattus norvegicus 16197 R-RNO-5339535 https://reactome.org/PathwayBrowser/#/R-RNO-5339535 CPTP transports C1P from plasma membrane to Golgi membrane IEA Rattus norvegicus 16197 R-SSC-1638845 https://reactome.org/PathwayBrowser/#/R-SSC-1638845 CERK phosphorylates CERA to form C1P IEA Sus scrofa 16197 R-XTR-1638845 https://reactome.org/PathwayBrowser/#/R-XTR-1638845 CERK phosphorylates CERA to form C1P IEA Xenopus tropicalis 16197 R-XTR-5339535 https://reactome.org/PathwayBrowser/#/R-XTR-5339535 CPTP transports C1P from plasma membrane to Golgi membrane IEA Xenopus tropicalis 16199 R-BTA-350604 https://reactome.org/PathwayBrowser/#/R-BTA-350604 Agmatine + H2O <=> putrescine + urea IEA Bos taurus 16199 R-BTA-444126 https://reactome.org/PathwayBrowser/#/R-BTA-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Bos taurus 16199 R-BTA-452036 https://reactome.org/PathwayBrowser/#/R-BTA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Bos taurus 16199 R-BTA-507873 https://reactome.org/PathwayBrowser/#/R-BTA-507873 Aquaporins passively transport urea out of cells IEA Bos taurus 16199 R-BTA-507875 https://reactome.org/PathwayBrowser/#/R-BTA-507875 Aquaporins passively transport urea into cells IEA Bos taurus 16199 R-BTA-70569 https://reactome.org/PathwayBrowser/#/R-BTA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Bos taurus 16199 R-CEL-452036 https://reactome.org/PathwayBrowser/#/R-CEL-452036 arginine + H2O => ornithine + urea [ARG2] IEA Caenorhabditis elegans 16199 R-CEL-507873 https://reactome.org/PathwayBrowser/#/R-CEL-507873 Aquaporins passively transport urea out of cells IEA Caenorhabditis elegans 16199 R-CEL-507875 https://reactome.org/PathwayBrowser/#/R-CEL-507875 Aquaporins passively transport urea into cells IEA Caenorhabditis elegans 16199 R-CEL-70569 https://reactome.org/PathwayBrowser/#/R-CEL-70569 arginine + H2O => ornithine + urea [ARG1] IEA Caenorhabditis elegans 16199 R-CFA-350604 https://reactome.org/PathwayBrowser/#/R-CFA-350604 Agmatine + H2O <=> putrescine + urea IEA Canis familiaris 16199 R-CFA-444126 https://reactome.org/PathwayBrowser/#/R-CFA-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Canis familiaris 16199 R-CFA-452036 https://reactome.org/PathwayBrowser/#/R-CFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Canis familiaris 16199 R-CFA-507873 https://reactome.org/PathwayBrowser/#/R-CFA-507873 Aquaporins passively transport urea out of cells IEA Canis familiaris 16199 R-CFA-507875 https://reactome.org/PathwayBrowser/#/R-CFA-507875 Aquaporins passively transport urea into cells IEA Canis familiaris 16199 R-CFA-70569 https://reactome.org/PathwayBrowser/#/R-CFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Canis familiaris 16199 R-DDI-444126 https://reactome.org/PathwayBrowser/#/R-DDI-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Dictyostelium discoideum 16199 R-DDI-452036 https://reactome.org/PathwayBrowser/#/R-DDI-452036 arginine + H2O => ornithine + urea [ARG2] IEA Dictyostelium discoideum 16199 R-DDI-70569 https://reactome.org/PathwayBrowser/#/R-DDI-70569 arginine + H2O => ornithine + urea [ARG1] IEA Dictyostelium discoideum 16199 R-DME-452036 https://reactome.org/PathwayBrowser/#/R-DME-452036 arginine + H2O => ornithine + urea [ARG2] IEA Drosophila melanogaster 16199 R-DME-70569 https://reactome.org/PathwayBrowser/#/R-DME-70569 arginine + H2O => ornithine + urea [ARG1] IEA Drosophila melanogaster 16199 R-DRE-350604 https://reactome.org/PathwayBrowser/#/R-DRE-350604 Agmatine + H2O <=> putrescine + urea IEA Danio rerio 16199 R-DRE-444126 https://reactome.org/PathwayBrowser/#/R-DRE-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Danio rerio 16199 R-DRE-452036 https://reactome.org/PathwayBrowser/#/R-DRE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Danio rerio 16199 R-DRE-507873 https://reactome.org/PathwayBrowser/#/R-DRE-507873 Aquaporins passively transport urea out of cells IEA Danio rerio 16199 R-DRE-507875 https://reactome.org/PathwayBrowser/#/R-DRE-507875 Aquaporins passively transport urea into cells IEA Danio rerio 16199 R-GGA-187632 https://reactome.org/PathwayBrowser/#/R-GGA-187632 arginine + H2O => ornithine + urea TAS Gallus gallus 16199 R-GGA-350604 https://reactome.org/PathwayBrowser/#/R-GGA-350604 Agmatine + H2O <=> putrescine + urea IEA Gallus gallus 16199 R-GGA-444126 https://reactome.org/PathwayBrowser/#/R-GGA-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Gallus gallus 16199 R-GGA-452036 https://reactome.org/PathwayBrowser/#/R-GGA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Gallus gallus 16199 R-GGA-507873 https://reactome.org/PathwayBrowser/#/R-GGA-507873 Aquaporins passively transport urea out of cells IEA Gallus gallus 16199 R-GGA-507875 https://reactome.org/PathwayBrowser/#/R-GGA-507875 Aquaporins passively transport urea into cells IEA Gallus gallus 16199 R-HSA-350604 https://reactome.org/PathwayBrowser/#/R-HSA-350604 Agmatine + H2O <=> putrescine + urea TAS Homo sapiens 16199 R-HSA-444126 https://reactome.org/PathwayBrowser/#/R-HSA-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively TAS Homo sapiens 16199 R-HSA-452036 https://reactome.org/PathwayBrowser/#/R-HSA-452036 arginine + H2O => ornithine + urea [ARG2] TAS Homo sapiens 16199 R-HSA-507873 https://reactome.org/PathwayBrowser/#/R-HSA-507873 Aquaporins passively transport urea out of cells TAS Homo sapiens 16199 R-HSA-507875 https://reactome.org/PathwayBrowser/#/R-HSA-507875 Aquaporins passively transport urea into cells TAS Homo sapiens 16199 R-HSA-70569 https://reactome.org/PathwayBrowser/#/R-HSA-70569 arginine + H2O => ornithine + urea [ARG1] TAS Homo sapiens 16199 R-MMU-350604 https://reactome.org/PathwayBrowser/#/R-MMU-350604 Agmatine + H2O <=> putrescine + urea IEA Mus musculus 16199 R-MMU-444126 https://reactome.org/PathwayBrowser/#/R-MMU-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Mus musculus 16199 R-MMU-452036 https://reactome.org/PathwayBrowser/#/R-MMU-452036 arginine + H2O => ornithine + urea [ARG2] IEA Mus musculus 16199 R-MMU-507873 https://reactome.org/PathwayBrowser/#/R-MMU-507873 Aquaporins passively transport urea out of cells IEA Mus musculus 16199 R-MMU-507875 https://reactome.org/PathwayBrowser/#/R-MMU-507875 Aquaporins passively transport urea into cells IEA Mus musculus 16199 R-MMU-70569 https://reactome.org/PathwayBrowser/#/R-MMU-70569 arginine + H2O => ornithine + urea [ARG1] IEA Mus musculus 16199 R-PFA-452036 https://reactome.org/PathwayBrowser/#/R-PFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Plasmodium falciparum 16199 R-PFA-507873 https://reactome.org/PathwayBrowser/#/R-PFA-507873 Aquaporins passively transport urea out of cells IEA Plasmodium falciparum 16199 R-PFA-507875 https://reactome.org/PathwayBrowser/#/R-PFA-507875 Aquaporins passively transport urea into cells IEA Plasmodium falciparum 16199 R-PFA-70569 https://reactome.org/PathwayBrowser/#/R-PFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Plasmodium falciparum 16199 R-RNO-350604 https://reactome.org/PathwayBrowser/#/R-RNO-350604 Agmatine + H2O <=> putrescine + urea IEA Rattus norvegicus 16199 R-RNO-444126 https://reactome.org/PathwayBrowser/#/R-RNO-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Rattus norvegicus 16199 R-RNO-452036 https://reactome.org/PathwayBrowser/#/R-RNO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Rattus norvegicus 16199 R-RNO-507873 https://reactome.org/PathwayBrowser/#/R-RNO-507873 Aquaporins passively transport urea out of cells IEA Rattus norvegicus 16199 R-RNO-507875 https://reactome.org/PathwayBrowser/#/R-RNO-507875 Aquaporins passively transport urea into cells IEA Rattus norvegicus 16199 R-RNO-70569 https://reactome.org/PathwayBrowser/#/R-RNO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Rattus norvegicus 16199 R-SCE-452036 https://reactome.org/PathwayBrowser/#/R-SCE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Saccharomyces cerevisiae 16199 R-SCE-507873 https://reactome.org/PathwayBrowser/#/R-SCE-507873 Aquaporins passively transport urea out of cells IEA Saccharomyces cerevisiae 16199 R-SCE-507875 https://reactome.org/PathwayBrowser/#/R-SCE-507875 Aquaporins passively transport urea into cells IEA Saccharomyces cerevisiae 16199 R-SCE-70569 https://reactome.org/PathwayBrowser/#/R-SCE-70569 arginine + H2O => ornithine + urea [ARG1] IEA Saccharomyces cerevisiae 16199 R-SPO-452036 https://reactome.org/PathwayBrowser/#/R-SPO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Schizosaccharomyces pombe 16199 R-SPO-507873 https://reactome.org/PathwayBrowser/#/R-SPO-507873 Aquaporins passively transport urea out of cells IEA Schizosaccharomyces pombe 16199 R-SPO-507875 https://reactome.org/PathwayBrowser/#/R-SPO-507875 Aquaporins passively transport urea into cells IEA Schizosaccharomyces pombe 16199 R-SPO-70569 https://reactome.org/PathwayBrowser/#/R-SPO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Schizosaccharomyces pombe 16199 R-SSC-350604 https://reactome.org/PathwayBrowser/#/R-SSC-350604 Agmatine + H2O <=> putrescine + urea IEA Sus scrofa 16199 R-SSC-444126 https://reactome.org/PathwayBrowser/#/R-SSC-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Sus scrofa 16199 R-SSC-452036 https://reactome.org/PathwayBrowser/#/R-SSC-452036 arginine + H2O => ornithine + urea [ARG2] IEA Sus scrofa 16199 R-SSC-507873 https://reactome.org/PathwayBrowser/#/R-SSC-507873 Aquaporins passively transport urea out of cells IEA Sus scrofa 16199 R-SSC-507875 https://reactome.org/PathwayBrowser/#/R-SSC-507875 Aquaporins passively transport urea into cells IEA Sus scrofa 16199 R-SSC-70569 https://reactome.org/PathwayBrowser/#/R-SSC-70569 arginine + H2O => ornithine + urea [ARG1] IEA Sus scrofa 16199 R-XTR-350604 https://reactome.org/PathwayBrowser/#/R-XTR-350604 Agmatine + H2O <=> putrescine + urea IEA Xenopus tropicalis 16199 R-XTR-444126 https://reactome.org/PathwayBrowser/#/R-XTR-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Xenopus tropicalis 16199 R-XTR-452036 https://reactome.org/PathwayBrowser/#/R-XTR-452036 arginine + H2O => ornithine + urea [ARG2] IEA Xenopus tropicalis 16199 R-XTR-507873 https://reactome.org/PathwayBrowser/#/R-XTR-507873 Aquaporins passively transport urea out of cells IEA Xenopus tropicalis 16199 R-XTR-507875 https://reactome.org/PathwayBrowser/#/R-XTR-507875 Aquaporins passively transport urea into cells IEA Xenopus tropicalis 16199 R-XTR-70569 https://reactome.org/PathwayBrowser/#/R-XTR-70569 arginine + H2O => ornithine + urea [ARG1] IEA Xenopus tropicalis 16208 R-BTA-9012721 https://reactome.org/PathwayBrowser/#/R-BTA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Bos taurus 16208 R-BTA-9013471 https://reactome.org/PathwayBrowser/#/R-BTA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Bos taurus 16208 R-BTA-9034756 https://reactome.org/PathwayBrowser/#/R-BTA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Bos taurus 16208 R-CEL-9012721 https://reactome.org/PathwayBrowser/#/R-CEL-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Caenorhabditis elegans 16208 R-CEL-9013471 https://reactome.org/PathwayBrowser/#/R-CEL-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Caenorhabditis elegans 16208 R-CEL-9034756 https://reactome.org/PathwayBrowser/#/R-CEL-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Caenorhabditis elegans 16208 R-CFA-9012721 https://reactome.org/PathwayBrowser/#/R-CFA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Canis familiaris 16208 R-CFA-9013471 https://reactome.org/PathwayBrowser/#/R-CFA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Canis familiaris 16208 R-CFA-9034756 https://reactome.org/PathwayBrowser/#/R-CFA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Canis familiaris 16208 R-DDI-9012721 https://reactome.org/PathwayBrowser/#/R-DDI-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Dictyostelium discoideum 16208 R-DDI-9013471 https://reactome.org/PathwayBrowser/#/R-DDI-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Dictyostelium discoideum 16208 R-DDI-9034756 https://reactome.org/PathwayBrowser/#/R-DDI-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Dictyostelium discoideum 16208 R-DRE-9012721 https://reactome.org/PathwayBrowser/#/R-DRE-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Danio rerio 16208 R-DRE-9013471 https://reactome.org/PathwayBrowser/#/R-DRE-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Danio rerio 16208 R-DRE-9034756 https://reactome.org/PathwayBrowser/#/R-DRE-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Danio rerio 16208 R-GGA-9012721 https://reactome.org/PathwayBrowser/#/R-GGA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Gallus gallus 16208 R-GGA-9013471 https://reactome.org/PathwayBrowser/#/R-GGA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Gallus gallus 16208 R-GGA-9034756 https://reactome.org/PathwayBrowser/#/R-GGA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Gallus gallus 16208 R-HSA-9012597 https://reactome.org/PathwayBrowser/#/R-HSA-9012597 GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu IEA Homo sapiens 16208 R-HSA-9012721 https://reactome.org/PathwayBrowser/#/R-HSA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR TAS Homo sapiens 16208 R-HSA-9013471 https://reactome.org/PathwayBrowser/#/R-HSA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN TAS Homo sapiens 16208 R-HSA-9034756 https://reactome.org/PathwayBrowser/#/R-HSA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST TAS Homo sapiens 16208 R-MMU-9012721 https://reactome.org/PathwayBrowser/#/R-MMU-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Mus musculus 16208 R-MMU-9013471 https://reactome.org/PathwayBrowser/#/R-MMU-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Mus musculus 16208 R-MMU-9034756 https://reactome.org/PathwayBrowser/#/R-MMU-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Mus musculus 16208 R-PFA-9012721 https://reactome.org/PathwayBrowser/#/R-PFA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Plasmodium falciparum 16208 R-PFA-9013471 https://reactome.org/PathwayBrowser/#/R-PFA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Plasmodium falciparum 16208 R-PFA-9034756 https://reactome.org/PathwayBrowser/#/R-PFA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Plasmodium falciparum 16208 R-RNO-9012709 https://reactome.org/PathwayBrowser/#/R-RNO-9012709 Got2:PLXP dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu TAS Rattus norvegicus 16208 R-RNO-9012721 https://reactome.org/PathwayBrowser/#/R-RNO-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Rattus norvegicus 16208 R-RNO-9013471 https://reactome.org/PathwayBrowser/#/R-RNO-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Rattus norvegicus 16208 R-RNO-9034756 https://reactome.org/PathwayBrowser/#/R-RNO-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Rattus norvegicus 16208 R-SCE-9012721 https://reactome.org/PathwayBrowser/#/R-SCE-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Saccharomyces cerevisiae 16208 R-SCE-9013471 https://reactome.org/PathwayBrowser/#/R-SCE-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Saccharomyces cerevisiae 16208 R-SCE-9034756 https://reactome.org/PathwayBrowser/#/R-SCE-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Saccharomyces cerevisiae 16208 R-SPO-9012721 https://reactome.org/PathwayBrowser/#/R-SPO-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Schizosaccharomyces pombe 16208 R-SPO-9013471 https://reactome.org/PathwayBrowser/#/R-SPO-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Schizosaccharomyces pombe 16208 R-SPO-9034756 https://reactome.org/PathwayBrowser/#/R-SPO-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Schizosaccharomyces pombe 16208 R-SSC-9012721 https://reactome.org/PathwayBrowser/#/R-SSC-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Sus scrofa 16208 R-SSC-9013471 https://reactome.org/PathwayBrowser/#/R-SSC-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Sus scrofa 16208 R-SSC-9034756 https://reactome.org/PathwayBrowser/#/R-SSC-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Sus scrofa 16208 R-XTR-9012721 https://reactome.org/PathwayBrowser/#/R-XTR-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Xenopus tropicalis 16208 R-XTR-9013471 https://reactome.org/PathwayBrowser/#/R-XTR-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Xenopus tropicalis 16208 R-XTR-9034756 https://reactome.org/PathwayBrowser/#/R-XTR-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Xenopus tropicalis 16223 R-BTA-5696213 https://reactome.org/PathwayBrowser/#/R-BTA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Bos taurus 16223 R-DRE-5696213 https://reactome.org/PathwayBrowser/#/R-DRE-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Danio rerio 16223 R-GGA-5696213 https://reactome.org/PathwayBrowser/#/R-GGA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Gallus gallus 16223 R-HSA-5696213 https://reactome.org/PathwayBrowser/#/R-HSA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite TAS Homo sapiens 16223 R-MMU-5696213 https://reactome.org/PathwayBrowser/#/R-MMU-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Mus musculus 16223 R-RNO-5696213 https://reactome.org/PathwayBrowser/#/R-RNO-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Rattus norvegicus 16223 R-SSC-5696213 https://reactome.org/PathwayBrowser/#/R-SSC-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Sus scrofa 16223 R-XTR-5696213 https://reactome.org/PathwayBrowser/#/R-XTR-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Xenopus tropicalis 16225 R-BTA-5692237 https://reactome.org/PathwayBrowser/#/R-BTA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Bos taurus 16225 R-BTA-5693724 https://reactome.org/PathwayBrowser/#/R-BTA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Bos taurus 16225 R-CEL-5692237 https://reactome.org/PathwayBrowser/#/R-CEL-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Caenorhabditis elegans 16225 R-CEL-5693724 https://reactome.org/PathwayBrowser/#/R-CEL-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Caenorhabditis elegans 16225 R-CFA-5692237 https://reactome.org/PathwayBrowser/#/R-CFA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Canis familiaris 16225 R-CFA-5693724 https://reactome.org/PathwayBrowser/#/R-CFA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Canis familiaris 16225 R-DDI-5692237 https://reactome.org/PathwayBrowser/#/R-DDI-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Dictyostelium discoideum 16225 R-DDI-5693724 https://reactome.org/PathwayBrowser/#/R-DDI-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Dictyostelium discoideum 16225 R-DME-5692237 https://reactome.org/PathwayBrowser/#/R-DME-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Drosophila melanogaster 16225 R-DME-5693724 https://reactome.org/PathwayBrowser/#/R-DME-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Drosophila melanogaster 16225 R-DRE-5692237 https://reactome.org/PathwayBrowser/#/R-DRE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Danio rerio 16225 R-DRE-5693724 https://reactome.org/PathwayBrowser/#/R-DRE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Danio rerio 16225 R-GGA-5692237 https://reactome.org/PathwayBrowser/#/R-GGA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Gallus gallus 16225 R-GGA-5693724 https://reactome.org/PathwayBrowser/#/R-GGA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Gallus gallus 16225 R-HSA-5692237 https://reactome.org/PathwayBrowser/#/R-HSA-5692237 ADH5 oxidises S-HMGSH to S-FGSH TAS Homo sapiens 16225 R-HSA-5693724 https://reactome.org/PathwayBrowser/#/R-HSA-5693724 ESD dimer hydrolyses S-FGSH to GSH TAS Homo sapiens 16225 R-MMU-5692237 https://reactome.org/PathwayBrowser/#/R-MMU-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Mus musculus 16225 R-MMU-5693724 https://reactome.org/PathwayBrowser/#/R-MMU-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Mus musculus 16225 R-RNO-5692237 https://reactome.org/PathwayBrowser/#/R-RNO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Rattus norvegicus 16225 R-RNO-5693724 https://reactome.org/PathwayBrowser/#/R-RNO-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Rattus norvegicus 16225 R-SCE-5692237 https://reactome.org/PathwayBrowser/#/R-SCE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Saccharomyces cerevisiae 16225 R-SCE-5693724 https://reactome.org/PathwayBrowser/#/R-SCE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Saccharomyces cerevisiae 16225 R-SPO-5692237 https://reactome.org/PathwayBrowser/#/R-SPO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Schizosaccharomyces pombe 16225 R-SSC-5692237 https://reactome.org/PathwayBrowser/#/R-SSC-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Sus scrofa 16225 R-SSC-5693724 https://reactome.org/PathwayBrowser/#/R-SSC-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Sus scrofa 16225 R-XTR-5692237 https://reactome.org/PathwayBrowser/#/R-XTR-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Xenopus tropicalis 16225 R-XTR-5693724 https://reactome.org/PathwayBrowser/#/R-XTR-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Xenopus tropicalis 16226 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 16226 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 16226 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 16226 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 16226 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 16226 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 16226 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 16226 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 16226 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 16226 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 16226 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 16226 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 16226 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 16226 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 16226 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 16226 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 16226 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 16226 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 16226 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 16226 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 16226 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 16226 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 16226 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 16226 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 16226 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 16226 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 16226 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 16226 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 16226 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 16226 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 16226 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 16226 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 16226 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 16226 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 16226 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 16226 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 16226 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 16226 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 16226 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 16226 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 16226 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 16226 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 16227 R-BTA-175987 https://reactome.org/PathwayBrowser/#/R-BTA-175987 NNMT transfers CH3 from AdoMet to PY IEA Bos taurus 16227 R-CEL-175987 https://reactome.org/PathwayBrowser/#/R-CEL-175987 NNMT transfers CH3 from AdoMet to PY IEA Caenorhabditis elegans 16227 R-CFA-175987 https://reactome.org/PathwayBrowser/#/R-CFA-175987 NNMT transfers CH3 from AdoMet to PY IEA Canis familiaris 16227 R-DRE-175987 https://reactome.org/PathwayBrowser/#/R-DRE-175987 NNMT transfers CH3 from AdoMet to PY IEA Danio rerio 16227 R-HSA-175987 https://reactome.org/PathwayBrowser/#/R-HSA-175987 NNMT transfers CH3 from AdoMet to PY TAS Homo sapiens 16227 R-MMU-175987 https://reactome.org/PathwayBrowser/#/R-MMU-175987 NNMT transfers CH3 from AdoMet to PY IEA Mus musculus 16227 R-RNO-175987 https://reactome.org/PathwayBrowser/#/R-RNO-175987 NNMT transfers CH3 from AdoMet to PY IEA Rattus norvegicus 16227 R-SSC-175987 https://reactome.org/PathwayBrowser/#/R-SSC-175987 NNMT transfers CH3 from AdoMet to PY IEA Sus scrofa 16227 R-XTR-175987 https://reactome.org/PathwayBrowser/#/R-XTR-175987 NNMT transfers CH3 from AdoMet to PY IEA Xenopus tropicalis 16234 R-BTA-9707504 https://reactome.org/PathwayBrowser/#/R-BTA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Bos taurus 16234 R-CFA-9707504 https://reactome.org/PathwayBrowser/#/R-CFA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Canis familiaris 16234 R-DRE-9707504 https://reactome.org/PathwayBrowser/#/R-DRE-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Danio rerio 16234 R-GGA-9707504 https://reactome.org/PathwayBrowser/#/R-GGA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Gallus gallus 16234 R-HSA-6789160 https://reactome.org/PathwayBrowser/#/R-HSA-6789160 Hydrogen peroxide and Fe2+ react to hydroxyl, hydroxide and Fe3+ TAS Homo sapiens 16234 R-HSA-9707504 https://reactome.org/PathwayBrowser/#/R-HSA-9707504 H2O2 oxidises ferrohemoglobin to MetHb TAS Homo sapiens 16234 R-MMU-9707504 https://reactome.org/PathwayBrowser/#/R-MMU-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Mus musculus 16234 R-RNO-9707504 https://reactome.org/PathwayBrowser/#/R-RNO-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Rattus norvegicus 16234 R-SSC-9707504 https://reactome.org/PathwayBrowser/#/R-SSC-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Sus scrofa 16234 R-XTR-9707504 https://reactome.org/PathwayBrowser/#/R-XTR-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Xenopus tropicalis 16235 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16235 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16235 R-BTA-112034 https://reactome.org/PathwayBrowser/#/R-BTA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Bos taurus 16235 R-BTA-74215 https://reactome.org/PathwayBrowser/#/R-BTA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Bos taurus 16235 R-BTA-74249 https://reactome.org/PathwayBrowser/#/R-BTA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Bos taurus 16235 R-BTA-74255 https://reactome.org/PathwayBrowser/#/R-BTA-74255 Guanine + H2O => Xanthine + NH4+ IEA Bos taurus 16235 R-BTA-8953339 https://reactome.org/PathwayBrowser/#/R-BTA-8953339 DNPH1 hydrolyses dGMP IEA Bos taurus 16235 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16235 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16235 R-CEL-112034 https://reactome.org/PathwayBrowser/#/R-CEL-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Caenorhabditis elegans 16235 R-CEL-74215 https://reactome.org/PathwayBrowser/#/R-CEL-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Caenorhabditis elegans 16235 R-CEL-74249 https://reactome.org/PathwayBrowser/#/R-CEL-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Caenorhabditis elegans 16235 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16235 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16235 R-CFA-112034 https://reactome.org/PathwayBrowser/#/R-CFA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Canis familiaris 16235 R-CFA-74215 https://reactome.org/PathwayBrowser/#/R-CFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Canis familiaris 16235 R-CFA-74249 https://reactome.org/PathwayBrowser/#/R-CFA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Canis familiaris 16235 R-CFA-74255 https://reactome.org/PathwayBrowser/#/R-CFA-74255 Guanine + H2O => Xanthine + NH4+ IEA Canis familiaris 16235 R-CFA-8953339 https://reactome.org/PathwayBrowser/#/R-CFA-8953339 DNPH1 hydrolyses dGMP IEA Canis familiaris 16235 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16235 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16235 R-DDI-74215 https://reactome.org/PathwayBrowser/#/R-DDI-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Dictyostelium discoideum 16235 R-DDI-74255 https://reactome.org/PathwayBrowser/#/R-DDI-74255 Guanine + H2O => Xanthine + NH4+ IEA Dictyostelium discoideum 16235 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16235 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16235 R-DME-112034 https://reactome.org/PathwayBrowser/#/R-DME-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Drosophila melanogaster 16235 R-DME-74249 https://reactome.org/PathwayBrowser/#/R-DME-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Drosophila melanogaster 16235 R-DME-74255 https://reactome.org/PathwayBrowser/#/R-DME-74255 Guanine + H2O => Xanthine + NH4+ IEA Drosophila melanogaster 16235 R-DRE-112034 https://reactome.org/PathwayBrowser/#/R-DRE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Danio rerio 16235 R-DRE-74215 https://reactome.org/PathwayBrowser/#/R-DRE-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Danio rerio 16235 R-DRE-74249 https://reactome.org/PathwayBrowser/#/R-DRE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Danio rerio 16235 R-DRE-74255 https://reactome.org/PathwayBrowser/#/R-DRE-74255 Guanine + H2O => Xanthine + NH4+ IEA Danio rerio 16235 R-DRE-8953339 https://reactome.org/PathwayBrowser/#/R-DRE-8953339 DNPH1 hydrolyses dGMP IEA Danio rerio 16235 R-GGA-74215 https://reactome.org/PathwayBrowser/#/R-GGA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Gallus gallus 16235 R-GGA-74255 https://reactome.org/PathwayBrowser/#/R-GGA-74255 Guanine + H2O => Xanthine + NH4+ IEA Gallus gallus 16235 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16235 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16235 R-HSA-112034 https://reactome.org/PathwayBrowser/#/R-HSA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine TAS Homo sapiens 16235 R-HSA-6782443 https://reactome.org/PathwayBrowser/#/R-HSA-6782443 QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr) TAS Homo sapiens 16235 R-HSA-74215 https://reactome.org/PathwayBrowser/#/R-HSA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 16235 R-HSA-74249 https://reactome.org/PathwayBrowser/#/R-HSA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 16235 R-HSA-74255 https://reactome.org/PathwayBrowser/#/R-HSA-74255 Guanine + H2O => Xanthine + NH4+ TAS Homo sapiens 16235 R-HSA-8953339 https://reactome.org/PathwayBrowser/#/R-HSA-8953339 DNPH1 hydrolyses dGMP TAS Homo sapiens 16235 R-HSA-9734274 https://reactome.org/PathwayBrowser/#/R-HSA-9734274 Defective HPRT1 does not convert guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 16235 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16235 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16235 R-MMU-112034 https://reactome.org/PathwayBrowser/#/R-MMU-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Mus musculus 16235 R-MMU-74215 https://reactome.org/PathwayBrowser/#/R-MMU-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Mus musculus 16235 R-MMU-74249 https://reactome.org/PathwayBrowser/#/R-MMU-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Mus musculus 16235 R-MMU-74255 https://reactome.org/PathwayBrowser/#/R-MMU-74255 Guanine + H2O => Xanthine + NH4+ IEA Mus musculus 16235 R-MMU-8953339 https://reactome.org/PathwayBrowser/#/R-MMU-8953339 DNPH1 hydrolyses dGMP IEA Mus musculus 16235 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16235 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16235 R-PFA-74215 https://reactome.org/PathwayBrowser/#/R-PFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Plasmodium falciparum 16235 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16235 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16235 R-RNO-112034 https://reactome.org/PathwayBrowser/#/R-RNO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Rattus norvegicus 16235 R-RNO-74215 https://reactome.org/PathwayBrowser/#/R-RNO-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Rattus norvegicus 16235 R-RNO-74249 https://reactome.org/PathwayBrowser/#/R-RNO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Rattus norvegicus 16235 R-RNO-74255 https://reactome.org/PathwayBrowser/#/R-RNO-74255 Guanine + H2O => Xanthine + NH4+ IEA Rattus norvegicus 16235 R-RNO-8953339 https://reactome.org/PathwayBrowser/#/R-RNO-8953339 DNPH1 hydrolyses dGMP IEA Rattus norvegicus 16235 R-SCE-112034 https://reactome.org/PathwayBrowser/#/R-SCE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Saccharomyces cerevisiae 16235 R-SCE-74249 https://reactome.org/PathwayBrowser/#/R-SCE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Saccharomyces cerevisiae 16235 R-SCE-74255 https://reactome.org/PathwayBrowser/#/R-SCE-74255 Guanine + H2O => Xanthine + NH4+ IEA Saccharomyces cerevisiae 16235 R-SPO-112034 https://reactome.org/PathwayBrowser/#/R-SPO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Schizosaccharomyces pombe 16235 R-SPO-74249 https://reactome.org/PathwayBrowser/#/R-SPO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Schizosaccharomyces pombe 16235 R-SPO-74255 https://reactome.org/PathwayBrowser/#/R-SPO-74255 Guanine + H2O => Xanthine + NH4+ IEA Schizosaccharomyces pombe 16235 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16235 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16235 R-SSC-112034 https://reactome.org/PathwayBrowser/#/R-SSC-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Sus scrofa 16235 R-SSC-74215 https://reactome.org/PathwayBrowser/#/R-SSC-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Sus scrofa 16235 R-SSC-74249 https://reactome.org/PathwayBrowser/#/R-SSC-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Sus scrofa 16235 R-SSC-74255 https://reactome.org/PathwayBrowser/#/R-SSC-74255 Guanine + H2O => Xanthine + NH4+ IEA Sus scrofa 16235 R-SSC-8953339 https://reactome.org/PathwayBrowser/#/R-SSC-8953339 DNPH1 hydrolyses dGMP IEA Sus scrofa 16235 R-XTR-112034 https://reactome.org/PathwayBrowser/#/R-XTR-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Xenopus tropicalis 16235 R-XTR-74249 https://reactome.org/PathwayBrowser/#/R-XTR-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Xenopus tropicalis 16235 R-XTR-74255 https://reactome.org/PathwayBrowser/#/R-XTR-74255 Guanine + H2O => Xanthine + NH4+ IEA Xenopus tropicalis 16236 R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 16236 R-BTA-71707 https://reactome.org/PathwayBrowser/#/R-BTA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Bos taurus 16236 R-BTA-9727567 https://reactome.org/PathwayBrowser/#/R-BTA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Bos taurus 16236 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 16236 R-CEL-71707 https://reactome.org/PathwayBrowser/#/R-CEL-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Caenorhabditis elegans 16236 R-CEL-9727567 https://reactome.org/PathwayBrowser/#/R-CEL-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Caenorhabditis elegans 16236 R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 16236 R-CFA-71707 https://reactome.org/PathwayBrowser/#/R-CFA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Canis familiaris 16236 R-CFA-9727567 https://reactome.org/PathwayBrowser/#/R-CFA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Canis familiaris 16236 R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 16236 R-DDI-71707 https://reactome.org/PathwayBrowser/#/R-DDI-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Dictyostelium discoideum 16236 R-DDI-9727567 https://reactome.org/PathwayBrowser/#/R-DDI-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Dictyostelium discoideum 16236 R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 16236 R-DME-71707 https://reactome.org/PathwayBrowser/#/R-DME-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Drosophila melanogaster 16236 R-DME-9727567 https://reactome.org/PathwayBrowser/#/R-DME-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Drosophila melanogaster 16236 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 16236 R-DRE-71707 https://reactome.org/PathwayBrowser/#/R-DRE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Danio rerio 16236 R-DRE-9727567 https://reactome.org/PathwayBrowser/#/R-DRE-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Danio rerio 16236 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 16236 R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus 16236 R-GGA-9727567 https://reactome.org/PathwayBrowser/#/R-GGA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Gallus gallus 16236 R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 16236 R-HSA-71707 https://reactome.org/PathwayBrowser/#/R-HSA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ TAS Homo sapiens 16236 R-HSA-9727567 https://reactome.org/PathwayBrowser/#/R-HSA-9727567 CES1 hydrolyses sacubitril to sacubitrilat TAS Homo sapiens 16236 R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 16236 R-MMU-71707 https://reactome.org/PathwayBrowser/#/R-MMU-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Mus musculus 16236 R-MMU-9727567 https://reactome.org/PathwayBrowser/#/R-MMU-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Mus musculus 16236 R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 16236 R-RNO-71707 https://reactome.org/PathwayBrowser/#/R-RNO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Rattus norvegicus 16236 R-RNO-9727567 https://reactome.org/PathwayBrowser/#/R-RNO-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Rattus norvegicus 16236 R-SCE-71707 https://reactome.org/PathwayBrowser/#/R-SCE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Saccharomyces cerevisiae 16236 R-SPO-71707 https://reactome.org/PathwayBrowser/#/R-SPO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Schizosaccharomyces pombe 16236 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 16236 R-SSC-71707 https://reactome.org/PathwayBrowser/#/R-SSC-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Sus scrofa 16236 R-SSC-9727567 https://reactome.org/PathwayBrowser/#/R-SSC-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Sus scrofa 16236 R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 16236 R-XTR-71707 https://reactome.org/PathwayBrowser/#/R-XTR-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Xenopus tropicalis 16236 R-XTR-9727567 https://reactome.org/PathwayBrowser/#/R-XTR-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Xenopus tropicalis 16240 R-BTA-141186 https://reactome.org/PathwayBrowser/#/R-BTA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Bos taurus 16240 R-BTA-141200 https://reactome.org/PathwayBrowser/#/R-BTA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Bos taurus 16240 R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus 16240 R-BTA-141341 https://reactome.org/PathwayBrowser/#/R-BTA-141341 SMOX-3 oxidises SPN to SPM IEA Bos taurus 16240 R-BTA-141348 https://reactome.org/PathwayBrowser/#/R-BTA-141348 PAO:FAD oxidises NASPM to PTCN IEA Bos taurus 16240 R-BTA-141351 https://reactome.org/PathwayBrowser/#/R-BTA-141351 PAOX:FAD oxidises NASPN to SPM IEA Bos taurus 16240 R-BTA-1614544 https://reactome.org/PathwayBrowser/#/R-BTA-1614544 Sulfite is oxidized to sulfate IEA Bos taurus 16240 R-BTA-189423 https://reactome.org/PathwayBrowser/#/R-BTA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Bos taurus 16240 R-BTA-192335 https://reactome.org/PathwayBrowser/#/R-BTA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Bos taurus 16240 R-BTA-193369 https://reactome.org/PathwayBrowser/#/R-BTA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Bos taurus 16240 R-BTA-2002466 https://reactome.org/PathwayBrowser/#/R-BTA-2002466 Formation of allysine by LOX IEA Bos taurus 16240 R-BTA-2066787 https://reactome.org/PathwayBrowser/#/R-BTA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Bos taurus 16240 R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 16240 R-BTA-2160492 https://reactome.org/PathwayBrowser/#/R-BTA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Bos taurus 16240 R-BTA-2395340 https://reactome.org/PathwayBrowser/#/R-BTA-2395340 Formation of hydroxyallysine by LOX IEA Bos taurus 16240 R-BTA-2559639 https://reactome.org/PathwayBrowser/#/R-BTA-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Bos taurus 16240 R-BTA-3204311 https://reactome.org/PathwayBrowser/#/R-BTA-3204311 AOX1 oxidises PXL to PDXate IEA Bos taurus 16240 R-BTA-3299680 https://reactome.org/PathwayBrowser/#/R-BTA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Bos taurus 16240 R-BTA-3299682 https://reactome.org/PathwayBrowser/#/R-BTA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Bos taurus 16240 R-BTA-3299691 https://reactome.org/PathwayBrowser/#/R-BTA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Bos taurus 16240 R-BTA-3322995 https://reactome.org/PathwayBrowser/#/R-BTA-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Bos taurus 16240 R-BTA-3323013 https://reactome.org/PathwayBrowser/#/R-BTA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 16240 R-BTA-3341296 https://reactome.org/PathwayBrowser/#/R-BTA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Bos taurus 16240 R-BTA-3341343 https://reactome.org/PathwayBrowser/#/R-BTA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Bos taurus 16240 R-BTA-3341397 https://reactome.org/PathwayBrowser/#/R-BTA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 16240 R-BTA-3343700 https://reactome.org/PathwayBrowser/#/R-BTA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 16240 R-BTA-350901 https://reactome.org/PathwayBrowser/#/R-BTA-350901 Iodide is organified IEA Bos taurus 16240 R-BTA-374909 https://reactome.org/PathwayBrowser/#/R-BTA-374909 Catabolism of Noradrenaline IEA Bos taurus 16240 R-BTA-3777112 https://reactome.org/PathwayBrowser/#/R-BTA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Bos taurus 16240 R-BTA-379382 https://reactome.org/PathwayBrowser/#/R-BTA-379382 MAOA:FAD deaminates DA to DOPAC IEA Bos taurus 16240 R-BTA-379395 https://reactome.org/PathwayBrowser/#/R-BTA-379395 MAOA:FAD deaminates 3MT to HVA IEA Bos taurus 16240 R-BTA-389821 https://reactome.org/PathwayBrowser/#/R-BTA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Bos taurus 16240 R-BTA-389842 https://reactome.org/PathwayBrowser/#/R-BTA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Bos taurus 16240 R-BTA-389862 https://reactome.org/PathwayBrowser/#/R-BTA-389862 Conversion of glyoxylate to oxalate IEA Bos taurus 16240 R-BTA-389889 https://reactome.org/PathwayBrowser/#/R-BTA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Bos taurus 16240 R-BTA-389891 https://reactome.org/PathwayBrowser/#/R-BTA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Bos taurus 16240 R-BTA-390256 https://reactome.org/PathwayBrowser/#/R-BTA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Bos taurus 16240 R-BTA-5631885 https://reactome.org/PathwayBrowser/#/R-BTA-5631885 PRDX1 overoxidizes IEA Bos taurus 16240 R-BTA-5693681 https://reactome.org/PathwayBrowser/#/R-BTA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Bos taurus 16240 R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 16240 R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 16240 R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 16240 R-BTA-6783880 https://reactome.org/PathwayBrowser/#/R-BTA-6783880 PIPOX oxidises PPCA to P6C IEA Bos taurus 16240 R-BTA-6787811 https://reactome.org/PathwayBrowser/#/R-BTA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Bos taurus 16240 R-BTA-6789031 https://reactome.org/PathwayBrowser/#/R-BTA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 16240 R-BTA-6789126 https://reactome.org/PathwayBrowser/#/R-BTA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 16240 R-BTA-6799695 https://reactome.org/PathwayBrowser/#/R-BTA-6799695 GPX5,6 reduce H2O2 to H2O IEA Bos taurus 16240 R-BTA-6810076 https://reactome.org/PathwayBrowser/#/R-BTA-6810076 DDO oxidizes D-Asp to OA IEA Bos taurus 16240 R-BTA-71676 https://reactome.org/PathwayBrowser/#/R-BTA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Bos taurus 16240 R-BTA-74247 https://reactome.org/PathwayBrowser/#/R-BTA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Bos taurus 16240 R-BTA-74258 https://reactome.org/PathwayBrowser/#/R-BTA-74258 XDH oxidizes xanthine to form urate IEA Bos taurus 16240 R-BTA-76031 https://reactome.org/PathwayBrowser/#/R-BTA-76031 2 H2O2 => O2 + 2 H2O IEA Bos taurus 16240 R-BTA-8855490 https://reactome.org/PathwayBrowser/#/R-BTA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Bos taurus 16240 R-BTA-8933635 https://reactome.org/PathwayBrowser/#/R-BTA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Bos taurus 16240 R-BTA-8956458 https://reactome.org/PathwayBrowser/#/R-BTA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Bos taurus 16240 R-BTA-965019 https://reactome.org/PathwayBrowser/#/R-BTA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Bos taurus 16240 R-BTA-965079 https://reactome.org/PathwayBrowser/#/R-BTA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Bos taurus 16240 R-BTA-9698408 https://reactome.org/PathwayBrowser/#/R-BTA-9698408 PTPRJ dephosphorylates active FLT3 IEA Bos taurus 16240 R-BTA-9707504 https://reactome.org/PathwayBrowser/#/R-BTA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Bos taurus 16240 R-BTA-9709360 https://reactome.org/PathwayBrowser/#/R-BTA-9709360 H2O2 reduces MetHb IEA Bos taurus 16240 R-BTA-9817575 https://reactome.org/PathwayBrowser/#/R-BTA-9817575 ERO1B oxidizes P4HB IEA Bos taurus 16240 R-BTA-9854368 https://reactome.org/PathwayBrowser/#/R-BTA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Bos taurus 16240 R-CEL-141348 https://reactome.org/PathwayBrowser/#/R-CEL-141348 PAO:FAD oxidises NASPM to PTCN IEA Caenorhabditis elegans 16240 R-CEL-141351 https://reactome.org/PathwayBrowser/#/R-CEL-141351 PAOX:FAD oxidises NASPN to SPM IEA Caenorhabditis elegans 16240 R-CEL-1614544 https://reactome.org/PathwayBrowser/#/R-CEL-1614544 Sulfite is oxidized to sulfate IEA Caenorhabditis elegans 16240 R-CEL-192335 https://reactome.org/PathwayBrowser/#/R-CEL-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Caenorhabditis elegans 16240 R-CEL-193369 https://reactome.org/PathwayBrowser/#/R-CEL-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Caenorhabditis elegans 16240 R-CEL-2066787 https://reactome.org/PathwayBrowser/#/R-CEL-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Caenorhabditis elegans 16240 R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 16240 R-CEL-3204311 https://reactome.org/PathwayBrowser/#/R-CEL-3204311 AOX1 oxidises PXL to PDXate IEA Caenorhabditis elegans 16240 R-CEL-3299680 https://reactome.org/PathwayBrowser/#/R-CEL-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Caenorhabditis elegans 16240 R-CEL-3299691 https://reactome.org/PathwayBrowser/#/R-CEL-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Caenorhabditis elegans 16240 R-CEL-3322995 https://reactome.org/PathwayBrowser/#/R-CEL-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Caenorhabditis elegans 16240 R-CEL-3341343 https://reactome.org/PathwayBrowser/#/R-CEL-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Caenorhabditis elegans 16240 R-CEL-3341397 https://reactome.org/PathwayBrowser/#/R-CEL-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Caenorhabditis elegans 16240 R-CEL-3343700 https://reactome.org/PathwayBrowser/#/R-CEL-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Caenorhabditis elegans 16240 R-CEL-350901 https://reactome.org/PathwayBrowser/#/R-CEL-350901 Iodide is organified IEA Caenorhabditis elegans 16240 R-CEL-3777112 https://reactome.org/PathwayBrowser/#/R-CEL-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Caenorhabditis elegans 16240 R-CEL-389821 https://reactome.org/PathwayBrowser/#/R-CEL-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Caenorhabditis elegans 16240 R-CEL-389842 https://reactome.org/PathwayBrowser/#/R-CEL-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Caenorhabditis elegans 16240 R-CEL-389862 https://reactome.org/PathwayBrowser/#/R-CEL-389862 Conversion of glyoxylate to oxalate IEA Caenorhabditis elegans 16240 R-CEL-389889 https://reactome.org/PathwayBrowser/#/R-CEL-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Caenorhabditis elegans 16240 R-CEL-389891 https://reactome.org/PathwayBrowser/#/R-CEL-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Caenorhabditis elegans 16240 R-CEL-390256 https://reactome.org/PathwayBrowser/#/R-CEL-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Caenorhabditis elegans 16240 R-CEL-5631885 https://reactome.org/PathwayBrowser/#/R-CEL-5631885 PRDX1 overoxidizes IEA Caenorhabditis elegans 16240 R-CEL-5693681 https://reactome.org/PathwayBrowser/#/R-CEL-5693681 DUOX1,2 reduce O2 to H2O2 IEA Caenorhabditis elegans 16240 R-CEL-6783880 https://reactome.org/PathwayBrowser/#/R-CEL-6783880 PIPOX oxidises PPCA to P6C IEA Caenorhabditis elegans 16240 R-CEL-6787811 https://reactome.org/PathwayBrowser/#/R-CEL-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Caenorhabditis elegans 16240 R-CEL-6789031 https://reactome.org/PathwayBrowser/#/R-CEL-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 16240 R-CEL-6789126 https://reactome.org/PathwayBrowser/#/R-CEL-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 16240 R-CEL-6799695 https://reactome.org/PathwayBrowser/#/R-CEL-6799695 GPX5,6 reduce H2O2 to H2O IEA Caenorhabditis elegans 16240 R-CEL-6810076 https://reactome.org/PathwayBrowser/#/R-CEL-6810076 DDO oxidizes D-Asp to OA IEA Caenorhabditis elegans 16240 R-CEL-74247 https://reactome.org/PathwayBrowser/#/R-CEL-74247 XDH oxidizes hypoxanthine to form xanthine IEA Caenorhabditis elegans 16240 R-CEL-74258 https://reactome.org/PathwayBrowser/#/R-CEL-74258 XDH oxidizes xanthine to form urate IEA Caenorhabditis elegans 16240 R-CEL-76031 https://reactome.org/PathwayBrowser/#/R-CEL-76031 2 H2O2 => O2 + 2 H2O IEA Caenorhabditis elegans 16240 R-CEL-8855490 https://reactome.org/PathwayBrowser/#/R-CEL-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Caenorhabditis elegans 16240 R-CEL-8865107 https://reactome.org/PathwayBrowser/#/R-CEL-8865107 MICAL1 produces NADP+, H2O2 IEA Caenorhabditis elegans 16240 R-CEL-8933635 https://reactome.org/PathwayBrowser/#/R-CEL-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Caenorhabditis elegans 16240 R-CEL-965019 https://reactome.org/PathwayBrowser/#/R-CEL-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Caenorhabditis elegans 16240 R-CEL-965079 https://reactome.org/PathwayBrowser/#/R-CEL-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Caenorhabditis elegans 16240 R-CEL-9817575 https://reactome.org/PathwayBrowser/#/R-CEL-9817575 ERO1B oxidizes P4HB IEA Caenorhabditis elegans 16240 R-CEL-9854368 https://reactome.org/PathwayBrowser/#/R-CEL-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Caenorhabditis elegans 16240 R-CFA-141186 https://reactome.org/PathwayBrowser/#/R-CFA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Canis familiaris 16240 R-CFA-141200 https://reactome.org/PathwayBrowser/#/R-CFA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Canis familiaris 16240 R-CFA-141202 https://reactome.org/PathwayBrowser/#/R-CFA-141202 MAOB:FAD oxidatively deaminates TYR IEA Canis familiaris 16240 R-CFA-141341 https://reactome.org/PathwayBrowser/#/R-CFA-141341 SMOX-3 oxidises SPN to SPM IEA Canis familiaris 16240 R-CFA-141348 https://reactome.org/PathwayBrowser/#/R-CFA-141348 PAO:FAD oxidises NASPM to PTCN IEA Canis familiaris 16240 R-CFA-141351 https://reactome.org/PathwayBrowser/#/R-CFA-141351 PAOX:FAD oxidises NASPN to SPM IEA Canis familiaris 16240 R-CFA-1614544 https://reactome.org/PathwayBrowser/#/R-CFA-1614544 Sulfite is oxidized to sulfate IEA Canis familiaris 16240 R-CFA-189423 https://reactome.org/PathwayBrowser/#/R-CFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Canis familiaris 16240 R-CFA-192335 https://reactome.org/PathwayBrowser/#/R-CFA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Canis familiaris 16240 R-CFA-193369 https://reactome.org/PathwayBrowser/#/R-CFA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Canis familiaris 16240 R-CFA-2002466 https://reactome.org/PathwayBrowser/#/R-CFA-2002466 Formation of allysine by LOX IEA Canis familiaris 16240 R-CFA-2066787 https://reactome.org/PathwayBrowser/#/R-CFA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Canis familiaris 16240 R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 16240 R-CFA-2160492 https://reactome.org/PathwayBrowser/#/R-CFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Canis familiaris 16240 R-CFA-2395340 https://reactome.org/PathwayBrowser/#/R-CFA-2395340 Formation of hydroxyallysine by LOX IEA Canis familiaris 16240 R-CFA-2559639 https://reactome.org/PathwayBrowser/#/R-CFA-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Canis familiaris 16240 R-CFA-3299680 https://reactome.org/PathwayBrowser/#/R-CFA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Canis familiaris 16240 R-CFA-3299682 https://reactome.org/PathwayBrowser/#/R-CFA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Canis familiaris 16240 R-CFA-3299691 https://reactome.org/PathwayBrowser/#/R-CFA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Canis familiaris 16240 R-CFA-3323013 https://reactome.org/PathwayBrowser/#/R-CFA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 16240 R-CFA-3341277 https://reactome.org/PathwayBrowser/#/R-CFA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 16240 R-CFA-3341296 https://reactome.org/PathwayBrowser/#/R-CFA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Canis familiaris 16240 R-CFA-3341343 https://reactome.org/PathwayBrowser/#/R-CFA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Canis familiaris 16240 R-CFA-3343700 https://reactome.org/PathwayBrowser/#/R-CFA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 16240 R-CFA-350901 https://reactome.org/PathwayBrowser/#/R-CFA-350901 Iodide is organified IEA Canis familiaris 16240 R-CFA-374909 https://reactome.org/PathwayBrowser/#/R-CFA-374909 Catabolism of Noradrenaline IEA Canis familiaris 16240 R-CFA-3777112 https://reactome.org/PathwayBrowser/#/R-CFA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Canis familiaris 16240 R-CFA-379382 https://reactome.org/PathwayBrowser/#/R-CFA-379382 MAOA:FAD deaminates DA to DOPAC IEA Canis familiaris 16240 R-CFA-379395 https://reactome.org/PathwayBrowser/#/R-CFA-379395 MAOA:FAD deaminates 3MT to HVA IEA Canis familiaris 16240 R-CFA-389821 https://reactome.org/PathwayBrowser/#/R-CFA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Canis familiaris 16240 R-CFA-389842 https://reactome.org/PathwayBrowser/#/R-CFA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Canis familiaris 16240 R-CFA-389862 https://reactome.org/PathwayBrowser/#/R-CFA-389862 Conversion of glyoxylate to oxalate IEA Canis familiaris 16240 R-CFA-389889 https://reactome.org/PathwayBrowser/#/R-CFA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Canis familiaris 16240 R-CFA-389891 https://reactome.org/PathwayBrowser/#/R-CFA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Canis familiaris 16240 R-CFA-390256 https://reactome.org/PathwayBrowser/#/R-CFA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Canis familiaris 16240 R-CFA-5631885 https://reactome.org/PathwayBrowser/#/R-CFA-5631885 PRDX1 overoxidizes IEA Canis familiaris 16240 R-CFA-5693681 https://reactome.org/PathwayBrowser/#/R-CFA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Canis familiaris 16240 R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 16240 R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 16240 R-CFA-6783880 https://reactome.org/PathwayBrowser/#/R-CFA-6783880 PIPOX oxidises PPCA to P6C IEA Canis familiaris 16240 R-CFA-6787811 https://reactome.org/PathwayBrowser/#/R-CFA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Canis familiaris 16240 R-CFA-6789031 https://reactome.org/PathwayBrowser/#/R-CFA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 16240 R-CFA-6789126 https://reactome.org/PathwayBrowser/#/R-CFA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 16240 R-CFA-6799695 https://reactome.org/PathwayBrowser/#/R-CFA-6799695 GPX5,6 reduce H2O2 to H2O IEA Canis familiaris 16240 R-CFA-6810076 https://reactome.org/PathwayBrowser/#/R-CFA-6810076 DDO oxidizes D-Asp to OA IEA Canis familiaris 16240 R-CFA-71676 https://reactome.org/PathwayBrowser/#/R-CFA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Canis familiaris 16240 R-CFA-74247 https://reactome.org/PathwayBrowser/#/R-CFA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Canis familiaris 16240 R-CFA-74258 https://reactome.org/PathwayBrowser/#/R-CFA-74258 XDH oxidizes xanthine to form urate IEA Canis familiaris 16240 R-CFA-76031 https://reactome.org/PathwayBrowser/#/R-CFA-76031 2 H2O2 => O2 + 2 H2O IEA Canis familiaris 16240 R-CFA-8855490 https://reactome.org/PathwayBrowser/#/R-CFA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Canis familiaris 16240 R-CFA-8933635 https://reactome.org/PathwayBrowser/#/R-CFA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Canis familiaris 16240 R-CFA-8956458 https://reactome.org/PathwayBrowser/#/R-CFA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Canis familiaris 16240 R-CFA-965019 https://reactome.org/PathwayBrowser/#/R-CFA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Canis familiaris 16240 R-CFA-965079 https://reactome.org/PathwayBrowser/#/R-CFA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Canis familiaris 16240 R-CFA-9698408 https://reactome.org/PathwayBrowser/#/R-CFA-9698408 PTPRJ dephosphorylates active FLT3 IEA Canis familiaris 16240 R-CFA-9707504 https://reactome.org/PathwayBrowser/#/R-CFA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Canis familiaris 16240 R-CFA-9709360 https://reactome.org/PathwayBrowser/#/R-CFA-9709360 H2O2 reduces MetHb IEA Canis familiaris 16240 R-CFA-9817575 https://reactome.org/PathwayBrowser/#/R-CFA-9817575 ERO1B oxidizes P4HB IEA Canis familiaris 16240 R-CFA-9854368 https://reactome.org/PathwayBrowser/#/R-CFA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Canis familiaris 16240 R-DDI-141186 https://reactome.org/PathwayBrowser/#/R-DDI-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Dictyostelium discoideum 16240 R-DDI-141200 https://reactome.org/PathwayBrowser/#/R-DDI-141200 MAOB:FAD oxidatively deaminates of PEA IEA Dictyostelium discoideum 16240 R-DDI-141202 https://reactome.org/PathwayBrowser/#/R-DDI-141202 MAOB:FAD oxidatively deaminates TYR IEA Dictyostelium discoideum 16240 R-DDI-1614544 https://reactome.org/PathwayBrowser/#/R-DDI-1614544 Sulfite is oxidized to sulfate IEA Dictyostelium discoideum 16240 R-DDI-189423 https://reactome.org/PathwayBrowser/#/R-DDI-189423 PPO oxidises PPGEN9 to PRIN9 IEA Dictyostelium discoideum 16240 R-DDI-192335 https://reactome.org/PathwayBrowser/#/R-DDI-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Dictyostelium discoideum 16240 R-DDI-193369 https://reactome.org/PathwayBrowser/#/R-DDI-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Dictyostelium discoideum 16240 R-DDI-2066787 https://reactome.org/PathwayBrowser/#/R-DDI-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Dictyostelium discoideum 16240 R-DDI-209973 https://reactome.org/PathwayBrowser/#/R-DDI-209973 Tyrosine is diiodinated IEA Dictyostelium discoideum 16240 R-DDI-2160492 https://reactome.org/PathwayBrowser/#/R-DDI-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Dictyostelium discoideum 16240 R-DDI-3204311 https://reactome.org/PathwayBrowser/#/R-DDI-3204311 AOX1 oxidises PXL to PDXate IEA Dictyostelium discoideum 16240 R-DDI-3299680 https://reactome.org/PathwayBrowser/#/R-DDI-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Dictyostelium discoideum 16240 R-DDI-3299682 https://reactome.org/PathwayBrowser/#/R-DDI-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Dictyostelium discoideum 16240 R-DDI-3299691 https://reactome.org/PathwayBrowser/#/R-DDI-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Dictyostelium discoideum 16240 R-DDI-3322995 https://reactome.org/PathwayBrowser/#/R-DDI-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Dictyostelium discoideum 16240 R-DDI-3341343 https://reactome.org/PathwayBrowser/#/R-DDI-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Dictyostelium discoideum 16240 R-DDI-3343700 https://reactome.org/PathwayBrowser/#/R-DDI-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Dictyostelium discoideum 16240 R-DDI-350901 https://reactome.org/PathwayBrowser/#/R-DDI-350901 Iodide is organified IEA Dictyostelium discoideum 16240 R-DDI-374909 https://reactome.org/PathwayBrowser/#/R-DDI-374909 Catabolism of Noradrenaline IEA Dictyostelium discoideum 16240 R-DDI-3777112 https://reactome.org/PathwayBrowser/#/R-DDI-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Dictyostelium discoideum 16240 R-DDI-379382 https://reactome.org/PathwayBrowser/#/R-DDI-379382 MAOA:FAD deaminates DA to DOPAC IEA Dictyostelium discoideum 16240 R-DDI-379395 https://reactome.org/PathwayBrowser/#/R-DDI-379395 MAOA:FAD deaminates 3MT to HVA IEA Dictyostelium discoideum 16240 R-DDI-389821 https://reactome.org/PathwayBrowser/#/R-DDI-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Dictyostelium discoideum 16240 R-DDI-389842 https://reactome.org/PathwayBrowser/#/R-DDI-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Dictyostelium discoideum 16240 R-DDI-389862 https://reactome.org/PathwayBrowser/#/R-DDI-389862 Conversion of glyoxylate to oxalate IEA Dictyostelium discoideum 16240 R-DDI-389889 https://reactome.org/PathwayBrowser/#/R-DDI-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Dictyostelium discoideum 16240 R-DDI-389891 https://reactome.org/PathwayBrowser/#/R-DDI-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Dictyostelium discoideum 16240 R-DDI-390256 https://reactome.org/PathwayBrowser/#/R-DDI-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Dictyostelium discoideum 16240 R-DDI-5631885 https://reactome.org/PathwayBrowser/#/R-DDI-5631885 PRDX1 overoxidizes IEA Dictyostelium discoideum 16240 R-DDI-5693681 https://reactome.org/PathwayBrowser/#/R-DDI-5693681 DUOX1,2 reduce O2 to H2O2 IEA Dictyostelium discoideum 16240 R-DDI-6783880 https://reactome.org/PathwayBrowser/#/R-DDI-6783880 PIPOX oxidises PPCA to P6C IEA Dictyostelium discoideum 16240 R-DDI-6787811 https://reactome.org/PathwayBrowser/#/R-DDI-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Dictyostelium discoideum 16240 R-DDI-6789031 https://reactome.org/PathwayBrowser/#/R-DDI-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 16240 R-DDI-6789126 https://reactome.org/PathwayBrowser/#/R-DDI-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 16240 R-DDI-6810076 https://reactome.org/PathwayBrowser/#/R-DDI-6810076 DDO oxidizes D-Asp to OA IEA Dictyostelium discoideum 16240 R-DDI-74247 https://reactome.org/PathwayBrowser/#/R-DDI-74247 XDH oxidizes hypoxanthine to form xanthine IEA Dictyostelium discoideum 16240 R-DDI-74258 https://reactome.org/PathwayBrowser/#/R-DDI-74258 XDH oxidizes xanthine to form urate IEA Dictyostelium discoideum 16240 R-DDI-76031 https://reactome.org/PathwayBrowser/#/R-DDI-76031 2 H2O2 => O2 + 2 H2O IEA Dictyostelium discoideum 16240 R-DDI-8855490 https://reactome.org/PathwayBrowser/#/R-DDI-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Dictyostelium discoideum 16240 R-DDI-8865107 https://reactome.org/PathwayBrowser/#/R-DDI-8865107 MICAL1 produces NADP+, H2O2 IEA Dictyostelium discoideum 16240 R-DDI-8933635 https://reactome.org/PathwayBrowser/#/R-DDI-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Dictyostelium discoideum 16240 R-DDI-965019 https://reactome.org/PathwayBrowser/#/R-DDI-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Dictyostelium discoideum 16240 R-DDI-965079 https://reactome.org/PathwayBrowser/#/R-DDI-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Dictyostelium discoideum 16240 R-DDI-9817575 https://reactome.org/PathwayBrowser/#/R-DDI-9817575 ERO1B oxidizes P4HB IEA Dictyostelium discoideum 16240 R-DDI-9854368 https://reactome.org/PathwayBrowser/#/R-DDI-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Dictyostelium discoideum 16240 R-DME-141341 https://reactome.org/PathwayBrowser/#/R-DME-141341 SMOX-3 oxidises SPN to SPM IEA Drosophila melanogaster 16240 R-DME-141348 https://reactome.org/PathwayBrowser/#/R-DME-141348 PAO:FAD oxidises NASPM to PTCN IEA Drosophila melanogaster 16240 R-DME-141351 https://reactome.org/PathwayBrowser/#/R-DME-141351 PAOX:FAD oxidises NASPN to SPM IEA Drosophila melanogaster 16240 R-DME-1614544 https://reactome.org/PathwayBrowser/#/R-DME-1614544 Sulfite is oxidized to sulfate IEA Drosophila melanogaster 16240 R-DME-189423 https://reactome.org/PathwayBrowser/#/R-DME-189423 PPO oxidises PPGEN9 to PRIN9 IEA Drosophila melanogaster 16240 R-DME-192335 https://reactome.org/PathwayBrowser/#/R-DME-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Drosophila melanogaster 16240 R-DME-193369 https://reactome.org/PathwayBrowser/#/R-DME-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Drosophila melanogaster 16240 R-DME-2066787 https://reactome.org/PathwayBrowser/#/R-DME-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Drosophila melanogaster 16240 R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 16240 R-DME-3204311 https://reactome.org/PathwayBrowser/#/R-DME-3204311 AOX1 oxidises PXL to PDXate IEA Drosophila melanogaster 16240 R-DME-3299680 https://reactome.org/PathwayBrowser/#/R-DME-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Drosophila melanogaster 16240 R-DME-3299691 https://reactome.org/PathwayBrowser/#/R-DME-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Drosophila melanogaster 16240 R-DME-3322995 https://reactome.org/PathwayBrowser/#/R-DME-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Drosophila melanogaster 16240 R-DME-3341343 https://reactome.org/PathwayBrowser/#/R-DME-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Drosophila melanogaster 16240 R-DME-350901 https://reactome.org/PathwayBrowser/#/R-DME-350901 Iodide is organified IEA Drosophila melanogaster 16240 R-DME-3777112 https://reactome.org/PathwayBrowser/#/R-DME-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Drosophila melanogaster 16240 R-DME-389821 https://reactome.org/PathwayBrowser/#/R-DME-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Drosophila melanogaster 16240 R-DME-389842 https://reactome.org/PathwayBrowser/#/R-DME-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Drosophila melanogaster 16240 R-DME-389862 https://reactome.org/PathwayBrowser/#/R-DME-389862 Conversion of glyoxylate to oxalate IEA Drosophila melanogaster 16240 R-DME-389889 https://reactome.org/PathwayBrowser/#/R-DME-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Drosophila melanogaster 16240 R-DME-389891 https://reactome.org/PathwayBrowser/#/R-DME-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Drosophila melanogaster 16240 R-DME-390256 https://reactome.org/PathwayBrowser/#/R-DME-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Drosophila melanogaster 16240 R-DME-5631885 https://reactome.org/PathwayBrowser/#/R-DME-5631885 PRDX1 overoxidizes IEA Drosophila melanogaster 16240 R-DME-5693681 https://reactome.org/PathwayBrowser/#/R-DME-5693681 DUOX1,2 reduce O2 to H2O2 IEA Drosophila melanogaster 16240 R-DME-6787811 https://reactome.org/PathwayBrowser/#/R-DME-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Drosophila melanogaster 16240 R-DME-6789031 https://reactome.org/PathwayBrowser/#/R-DME-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 16240 R-DME-6789126 https://reactome.org/PathwayBrowser/#/R-DME-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 16240 R-DME-6810076 https://reactome.org/PathwayBrowser/#/R-DME-6810076 DDO oxidizes D-Asp to OA IEA Drosophila melanogaster 16240 R-DME-74247 https://reactome.org/PathwayBrowser/#/R-DME-74247 XDH oxidizes hypoxanthine to form xanthine IEA Drosophila melanogaster 16240 R-DME-74258 https://reactome.org/PathwayBrowser/#/R-DME-74258 XDH oxidizes xanthine to form urate IEA Drosophila melanogaster 16240 R-DME-76031 https://reactome.org/PathwayBrowser/#/R-DME-76031 2 H2O2 => O2 + 2 H2O IEA Drosophila melanogaster 16240 R-DME-8855490 https://reactome.org/PathwayBrowser/#/R-DME-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Drosophila melanogaster 16240 R-DME-8933635 https://reactome.org/PathwayBrowser/#/R-DME-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Drosophila melanogaster 16240 R-DME-965019 https://reactome.org/PathwayBrowser/#/R-DME-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Drosophila melanogaster 16240 R-DME-965079 https://reactome.org/PathwayBrowser/#/R-DME-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Drosophila melanogaster 16240 R-DME-9817575 https://reactome.org/PathwayBrowser/#/R-DME-9817575 ERO1B oxidizes P4HB IEA Drosophila melanogaster 16240 R-DME-9854368 https://reactome.org/PathwayBrowser/#/R-DME-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Drosophila melanogaster 16240 R-DRE-141200 https://reactome.org/PathwayBrowser/#/R-DRE-141200 MAOB:FAD oxidatively deaminates of PEA IEA Danio rerio 16240 R-DRE-141202 https://reactome.org/PathwayBrowser/#/R-DRE-141202 MAOB:FAD oxidatively deaminates TYR IEA Danio rerio 16240 R-DRE-141348 https://reactome.org/PathwayBrowser/#/R-DRE-141348 PAO:FAD oxidises NASPM to PTCN IEA Danio rerio 16240 R-DRE-141351 https://reactome.org/PathwayBrowser/#/R-DRE-141351 PAOX:FAD oxidises NASPN to SPM IEA Danio rerio 16240 R-DRE-189423 https://reactome.org/PathwayBrowser/#/R-DRE-189423 PPO oxidises PPGEN9 to PRIN9 IEA Danio rerio 16240 R-DRE-2002466 https://reactome.org/PathwayBrowser/#/R-DRE-2002466 Formation of allysine by LOX IEA Danio rerio 16240 R-DRE-2066787 https://reactome.org/PathwayBrowser/#/R-DRE-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Danio rerio 16240 R-DRE-2395340 https://reactome.org/PathwayBrowser/#/R-DRE-2395340 Formation of hydroxyallysine by LOX IEA Danio rerio 16240 R-DRE-3204311 https://reactome.org/PathwayBrowser/#/R-DRE-3204311 AOX1 oxidises PXL to PDXate IEA Danio rerio 16240 R-DRE-3299680 https://reactome.org/PathwayBrowser/#/R-DRE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Danio rerio 16240 R-DRE-3299682 https://reactome.org/PathwayBrowser/#/R-DRE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Danio rerio 16240 R-DRE-3299691 https://reactome.org/PathwayBrowser/#/R-DRE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Danio rerio 16240 R-DRE-3322995 https://reactome.org/PathwayBrowser/#/R-DRE-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Danio rerio 16240 R-DRE-3341296 https://reactome.org/PathwayBrowser/#/R-DRE-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Danio rerio 16240 R-DRE-3341343 https://reactome.org/PathwayBrowser/#/R-DRE-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Danio rerio 16240 R-DRE-3343700 https://reactome.org/PathwayBrowser/#/R-DRE-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Danio rerio 16240 R-DRE-3777112 https://reactome.org/PathwayBrowser/#/R-DRE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Danio rerio 16240 R-DRE-389821 https://reactome.org/PathwayBrowser/#/R-DRE-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Danio rerio 16240 R-DRE-389842 https://reactome.org/PathwayBrowser/#/R-DRE-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Danio rerio 16240 R-DRE-389862 https://reactome.org/PathwayBrowser/#/R-DRE-389862 Conversion of glyoxylate to oxalate IEA Danio rerio 16240 R-DRE-389891 https://reactome.org/PathwayBrowser/#/R-DRE-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Danio rerio 16240 R-DRE-390256 https://reactome.org/PathwayBrowser/#/R-DRE-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Danio rerio 16240 R-DRE-5631885 https://reactome.org/PathwayBrowser/#/R-DRE-5631885 PRDX1 overoxidizes IEA Danio rerio 16240 R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 16240 R-DRE-6799695 https://reactome.org/PathwayBrowser/#/R-DRE-6799695 GPX5,6 reduce H2O2 to H2O IEA Danio rerio 16240 R-DRE-76031 https://reactome.org/PathwayBrowser/#/R-DRE-76031 2 H2O2 => O2 + 2 H2O IEA Danio rerio 16240 R-DRE-8865107 https://reactome.org/PathwayBrowser/#/R-DRE-8865107 MICAL1 produces NADP+, H2O2 IEA Danio rerio 16240 R-DRE-8956458 https://reactome.org/PathwayBrowser/#/R-DRE-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Danio rerio 16240 R-DRE-9707504 https://reactome.org/PathwayBrowser/#/R-DRE-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Danio rerio 16240 R-DRE-9709360 https://reactome.org/PathwayBrowser/#/R-DRE-9709360 H2O2 reduces MetHb IEA Danio rerio 16240 R-DRE-9854368 https://reactome.org/PathwayBrowser/#/R-DRE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Danio rerio 16240 R-GGA-141186 https://reactome.org/PathwayBrowser/#/R-GGA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Gallus gallus 16240 R-GGA-141200 https://reactome.org/PathwayBrowser/#/R-GGA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Gallus gallus 16240 R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus 16240 R-GGA-141341 https://reactome.org/PathwayBrowser/#/R-GGA-141341 SMOX-3 oxidises SPN to SPM IEA Gallus gallus 16240 R-GGA-141348 https://reactome.org/PathwayBrowser/#/R-GGA-141348 PAO:FAD oxidises NASPM to PTCN IEA Gallus gallus 16240 R-GGA-141351 https://reactome.org/PathwayBrowser/#/R-GGA-141351 PAOX:FAD oxidises NASPN to SPM IEA Gallus gallus 16240 R-GGA-1614544 https://reactome.org/PathwayBrowser/#/R-GGA-1614544 Sulfite is oxidized to sulfate IEA Gallus gallus 16240 R-GGA-189423 https://reactome.org/PathwayBrowser/#/R-GGA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Gallus gallus 16240 R-GGA-192335 https://reactome.org/PathwayBrowser/#/R-GGA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Gallus gallus 16240 R-GGA-193369 https://reactome.org/PathwayBrowser/#/R-GGA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Gallus gallus 16240 R-GGA-2002466 https://reactome.org/PathwayBrowser/#/R-GGA-2002466 Formation of allysine by LOX IEA Gallus gallus 16240 R-GGA-2066787 https://reactome.org/PathwayBrowser/#/R-GGA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Gallus gallus 16240 R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 16240 R-GGA-2395340 https://reactome.org/PathwayBrowser/#/R-GGA-2395340 Formation of hydroxyallysine by LOX IEA Gallus gallus 16240 R-GGA-2559639 https://reactome.org/PathwayBrowser/#/R-GGA-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Gallus gallus 16240 R-GGA-3204311 https://reactome.org/PathwayBrowser/#/R-GGA-3204311 AOX1 oxidises PXL to PDXate IEA Gallus gallus 16240 R-GGA-3299680 https://reactome.org/PathwayBrowser/#/R-GGA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Gallus gallus 16240 R-GGA-3299682 https://reactome.org/PathwayBrowser/#/R-GGA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Gallus gallus 16240 R-GGA-3299691 https://reactome.org/PathwayBrowser/#/R-GGA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Gallus gallus 16240 R-GGA-3322995 https://reactome.org/PathwayBrowser/#/R-GGA-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Gallus gallus 16240 R-GGA-3341277 https://reactome.org/PathwayBrowser/#/R-GGA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Gallus gallus 16240 R-GGA-3341296 https://reactome.org/PathwayBrowser/#/R-GGA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Gallus gallus 16240 R-GGA-3341343 https://reactome.org/PathwayBrowser/#/R-GGA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Gallus gallus 16240 R-GGA-3341397 https://reactome.org/PathwayBrowser/#/R-GGA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Gallus gallus 16240 R-GGA-350901 https://reactome.org/PathwayBrowser/#/R-GGA-350901 Iodide is organified IEA Gallus gallus 16240 R-GGA-374909 https://reactome.org/PathwayBrowser/#/R-GGA-374909 Catabolism of Noradrenaline IEA Gallus gallus 16240 R-GGA-3777112 https://reactome.org/PathwayBrowser/#/R-GGA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Gallus gallus 16240 R-GGA-379382 https://reactome.org/PathwayBrowser/#/R-GGA-379382 MAOA:FAD deaminates DA to DOPAC IEA Gallus gallus 16240 R-GGA-379395 https://reactome.org/PathwayBrowser/#/R-GGA-379395 MAOA:FAD deaminates 3MT to HVA IEA Gallus gallus 16240 R-GGA-389821 https://reactome.org/PathwayBrowser/#/R-GGA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Gallus gallus 16240 R-GGA-389842 https://reactome.org/PathwayBrowser/#/R-GGA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Gallus gallus 16240 R-GGA-389862 https://reactome.org/PathwayBrowser/#/R-GGA-389862 Conversion of glyoxylate to oxalate IEA Gallus gallus 16240 R-GGA-389889 https://reactome.org/PathwayBrowser/#/R-GGA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Gallus gallus 16240 R-GGA-389891 https://reactome.org/PathwayBrowser/#/R-GGA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Gallus gallus 16240 R-GGA-390256 https://reactome.org/PathwayBrowser/#/R-GGA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Gallus gallus 16240 R-GGA-421478 https://reactome.org/PathwayBrowser/#/R-GGA-421478 coproporphyrinogen III + 2 O2 => protoporphyrinogen IX + 2 H2O2 + 2 CO2 IEA Gallus gallus 16240 R-GGA-5631885 https://reactome.org/PathwayBrowser/#/R-GGA-5631885 PRDX1 overoxidizes IEA Gallus gallus 16240 R-GGA-5693681 https://reactome.org/PathwayBrowser/#/R-GGA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Gallus gallus 16240 R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 16240 R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 16240 R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 16240 R-GGA-6783880 https://reactome.org/PathwayBrowser/#/R-GGA-6783880 PIPOX oxidises PPCA to P6C IEA Gallus gallus 16240 R-GGA-6787811 https://reactome.org/PathwayBrowser/#/R-GGA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Gallus gallus 16240 R-GGA-6789031 https://reactome.org/PathwayBrowser/#/R-GGA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 16240 R-GGA-6789126 https://reactome.org/PathwayBrowser/#/R-GGA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 16240 R-GGA-6810076 https://reactome.org/PathwayBrowser/#/R-GGA-6810076 DDO oxidizes D-Asp to OA IEA Gallus gallus 16240 R-GGA-74247 https://reactome.org/PathwayBrowser/#/R-GGA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Gallus gallus 16240 R-GGA-74258 https://reactome.org/PathwayBrowser/#/R-GGA-74258 XDH oxidizes xanthine to form urate IEA Gallus gallus 16240 R-GGA-76031 https://reactome.org/PathwayBrowser/#/R-GGA-76031 2 H2O2 => O2 + 2 H2O IEA Gallus gallus 16240 R-GGA-8855490 https://reactome.org/PathwayBrowser/#/R-GGA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Gallus gallus 16240 R-GGA-8865107 https://reactome.org/PathwayBrowser/#/R-GGA-8865107 MICAL1 produces NADP+, H2O2 IEA Gallus gallus 16240 R-GGA-8933635 https://reactome.org/PathwayBrowser/#/R-GGA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Gallus gallus 16240 R-GGA-8956458 https://reactome.org/PathwayBrowser/#/R-GGA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Gallus gallus 16240 R-GGA-965019 https://reactome.org/PathwayBrowser/#/R-GGA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Gallus gallus 16240 R-GGA-965079 https://reactome.org/PathwayBrowser/#/R-GGA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Gallus gallus 16240 R-GGA-9707504 https://reactome.org/PathwayBrowser/#/R-GGA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Gallus gallus 16240 R-GGA-9709360 https://reactome.org/PathwayBrowser/#/R-GGA-9709360 H2O2 reduces MetHb IEA Gallus gallus 16240 R-GGA-9817575 https://reactome.org/PathwayBrowser/#/R-GGA-9817575 ERO1B oxidizes P4HB IEA Gallus gallus 16240 R-GGA-9854368 https://reactome.org/PathwayBrowser/#/R-GGA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Gallus gallus 16240 R-HSA-1222341 https://reactome.org/PathwayBrowser/#/R-HSA-1222341 H2O2 gets scavenged by unsaturated lipid TAS Homo sapiens 16240 R-HSA-1222346 https://reactome.org/PathwayBrowser/#/R-HSA-1222346 AhpC reduces H2O2 TAS Homo sapiens 16240 R-HSA-1222462 https://reactome.org/PathwayBrowser/#/R-HSA-1222462 SodB reduces superoxide to H2O2 TAS Homo sapiens 16240 R-HSA-1222469 https://reactome.org/PathwayBrowser/#/R-HSA-1222469 SodC reduces superoxide to H2O2 TAS Homo sapiens 16240 R-HSA-1222704 https://reactome.org/PathwayBrowser/#/R-HSA-1222704 KatG reduces H2O2 TAS Homo sapiens 16240 R-HSA-141186 https://reactome.org/PathwayBrowser/#/R-HSA-141186 MAOA:FAD oxidatively deaminates of 5HT TAS Homo sapiens 16240 R-HSA-141200 https://reactome.org/PathwayBrowser/#/R-HSA-141200 MAOB:FAD oxidatively deaminates of PEA TAS Homo sapiens 16240 R-HSA-141202 https://reactome.org/PathwayBrowser/#/R-HSA-141202 MAOB:FAD oxidatively deaminates TYR TAS Homo sapiens 16240 R-HSA-141341 https://reactome.org/PathwayBrowser/#/R-HSA-141341 SMOX-3 oxidises SPN to SPM TAS Homo sapiens 16240 R-HSA-141348 https://reactome.org/PathwayBrowser/#/R-HSA-141348 PAO:FAD oxidises NASPM to PTCN TAS Homo sapiens 16240 R-HSA-141351 https://reactome.org/PathwayBrowser/#/R-HSA-141351 PAOX:FAD oxidises NASPN to SPM TAS Homo sapiens 16240 R-HSA-1614544 https://reactome.org/PathwayBrowser/#/R-HSA-1614544 Sulfite is oxidized to sulfate TAS Homo sapiens 16240 R-HSA-189423 https://reactome.org/PathwayBrowser/#/R-HSA-189423 PPO oxidises PPGEN9 to PRIN9 TAS Homo sapiens 16240 R-HSA-192335 https://reactome.org/PathwayBrowser/#/R-HSA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) TAS Homo sapiens 16240 R-HSA-193369 https://reactome.org/PathwayBrowser/#/R-HSA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA TAS Homo sapiens 16240 R-HSA-2002466 https://reactome.org/PathwayBrowser/#/R-HSA-2002466 Formation of allysine by LOX TAS Homo sapiens 16240 R-HSA-2066787 https://reactome.org/PathwayBrowser/#/R-HSA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA TAS Homo sapiens 16240 R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 16240 R-HSA-2160492 https://reactome.org/PathwayBrowser/#/R-HSA-2160492 IL4I1:FAD oxidises L-Phe to kPPV TAS Homo sapiens 16240 R-HSA-2395340 https://reactome.org/PathwayBrowser/#/R-HSA-2395340 Formation of hydroxyallysine by LOX TAS Homo sapiens 16240 R-HSA-2559639 https://reactome.org/PathwayBrowser/#/R-HSA-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin TAS Homo sapiens 16240 R-HSA-3204311 https://reactome.org/PathwayBrowser/#/R-HSA-3204311 AOX1 oxidises PXL to PDXate TAS Homo sapiens 16240 R-HSA-3299680 https://reactome.org/PathwayBrowser/#/R-HSA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) TAS Homo sapiens 16240 R-HSA-3299682 https://reactome.org/PathwayBrowser/#/R-HSA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) TAS Homo sapiens 16240 R-HSA-3299691 https://reactome.org/PathwayBrowser/#/R-HSA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) TAS Homo sapiens 16240 R-HSA-3322995 https://reactome.org/PathwayBrowser/#/R-HSA-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O TAS Homo sapiens 16240 R-HSA-3323013 https://reactome.org/PathwayBrowser/#/R-HSA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 16240 R-HSA-3341277 https://reactome.org/PathwayBrowser/#/R-HSA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 16240 R-HSA-3341296 https://reactome.org/PathwayBrowser/#/R-HSA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) TAS Homo sapiens 16240 R-HSA-3341343 https://reactome.org/PathwayBrowser/#/R-HSA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O TAS Homo sapiens 16240 R-HSA-3341397 https://reactome.org/PathwayBrowser/#/R-HSA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 16240 R-HSA-3343700 https://reactome.org/PathwayBrowser/#/R-HSA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 16240 R-HSA-350901 https://reactome.org/PathwayBrowser/#/R-HSA-350901 Iodide is organified TAS Homo sapiens 16240 R-HSA-374909 https://reactome.org/PathwayBrowser/#/R-HSA-374909 Catabolism of Noradrenaline TAS Homo sapiens 16240 R-HSA-3777112 https://reactome.org/PathwayBrowser/#/R-HSA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) TAS Homo sapiens 16240 R-HSA-3779381 https://reactome.org/PathwayBrowser/#/R-HSA-3779381 H2O2 diffuses from the mitochondrial matrix to the cytosol IEA Homo sapiens 16240 R-HSA-379382 https://reactome.org/PathwayBrowser/#/R-HSA-379382 MAOA:FAD deaminates DA to DOPAC TAS Homo sapiens 16240 R-HSA-379395 https://reactome.org/PathwayBrowser/#/R-HSA-379395 MAOA:FAD deaminates 3MT to HVA TAS Homo sapiens 16240 R-HSA-389821 https://reactome.org/PathwayBrowser/#/R-HSA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ TAS Homo sapiens 16240 R-HSA-389842 https://reactome.org/PathwayBrowser/#/R-HSA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate TAS Homo sapiens 16240 R-HSA-389862 https://reactome.org/PathwayBrowser/#/R-HSA-389862 Conversion of glyoxylate to oxalate TAS Homo sapiens 16240 R-HSA-389889 https://reactome.org/PathwayBrowser/#/R-HSA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA TAS Homo sapiens 16240 R-HSA-389891 https://reactome.org/PathwayBrowser/#/R-HSA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) TAS Homo sapiens 16240 R-HSA-390256 https://reactome.org/PathwayBrowser/#/R-HSA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 TAS Homo sapiens 16240 R-HSA-390276 https://reactome.org/PathwayBrowser/#/R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA TAS Homo sapiens 16240 R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA TAS Homo sapiens 16240 R-HSA-5631885 https://reactome.org/PathwayBrowser/#/R-HSA-5631885 PRDX1 overoxidizes TAS Homo sapiens 16240 R-HSA-5676912 https://reactome.org/PathwayBrowser/#/R-HSA-5676912 Methionine is oxidised to methionine sulfoxide TAS Homo sapiens 16240 R-HSA-5676926 https://reactome.org/PathwayBrowser/#/R-HSA-5676926 Methionine sulfoxide is oxidised to methionine sulfone TAS Homo sapiens 16240 R-HSA-5693681 https://reactome.org/PathwayBrowser/#/R-HSA-5693681 DUOX1,2 reduce O2 to H2O2 TAS Homo sapiens 16240 R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 16240 R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 16240 R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 16240 R-HSA-6783880 https://reactome.org/PathwayBrowser/#/R-HSA-6783880 PIPOX oxidises PPCA to P6C TAS Homo sapiens 16240 R-HSA-6787811 https://reactome.org/PathwayBrowser/#/R-HSA-6787811 HAO2 tetramer oxidises 2OH-PALM TAS Homo sapiens 16240 R-HSA-6788975 https://reactome.org/PathwayBrowser/#/R-HSA-6788975 Superoxide anion dismutates to H2O2 TAS Homo sapiens 16240 R-HSA-6789031 https://reactome.org/PathwayBrowser/#/R-HSA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 16240 R-HSA-6789077 https://reactome.org/PathwayBrowser/#/R-HSA-6789077 Hydrogen peroxide enters the bacterium TAS Homo sapiens 16240 R-HSA-6789109 https://reactome.org/PathwayBrowser/#/R-HSA-6789109 Superoxide anion reacts with Fe-S cluster TAS Homo sapiens 16240 R-HSA-6789126 https://reactome.org/PathwayBrowser/#/R-HSA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 16240 R-HSA-6789160 https://reactome.org/PathwayBrowser/#/R-HSA-6789160 Hydrogen peroxide and Fe2+ react to hydroxyl, hydroxide and Fe3+ TAS Homo sapiens 16240 R-HSA-6799695 https://reactome.org/PathwayBrowser/#/R-HSA-6799695 GPX5,6 reduce H2O2 to H2O TAS Homo sapiens 16240 R-HSA-6810076 https://reactome.org/PathwayBrowser/#/R-HSA-6810076 DDO oxidizes D-Asp to OA TAS Homo sapiens 16240 R-HSA-71676 https://reactome.org/PathwayBrowser/#/R-HSA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O TAS Homo sapiens 16240 R-HSA-74247 https://reactome.org/PathwayBrowser/#/R-HSA-74247 XDH oxidizes hypoxanthine to form xanthine TAS Homo sapiens 16240 R-HSA-74258 https://reactome.org/PathwayBrowser/#/R-HSA-74258 XDH oxidizes xanthine to form urate TAS Homo sapiens 16240 R-HSA-76031 https://reactome.org/PathwayBrowser/#/R-HSA-76031 2 H2O2 => O2 + 2 H2O TAS Homo sapiens 16240 R-HSA-8855490 https://reactome.org/PathwayBrowser/#/R-HSA-8855490 Lactoperoxidase (LPO) produces OSCN- TAS Homo sapiens 16240 R-HSA-8865107 https://reactome.org/PathwayBrowser/#/R-HSA-8865107 MICAL1 produces NADP+, H2O2 TAS Homo sapiens 16240 R-HSA-8933635 https://reactome.org/PathwayBrowser/#/R-HSA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide TAS Homo sapiens 16240 R-HSA-8956458 https://reactome.org/PathwayBrowser/#/R-HSA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ TAS Homo sapiens 16240 R-HSA-9626753 https://reactome.org/PathwayBrowser/#/R-HSA-9626753 H2O2 oxidizes Cys residues to form Cys-sulfenic acid TAS Homo sapiens 16240 R-HSA-9640316 https://reactome.org/PathwayBrowser/#/R-HSA-9640316 DeHA hydrolyses to threonate and oxalate TAS Homo sapiens 16240 R-HSA-965019 https://reactome.org/PathwayBrowser/#/R-HSA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP TAS Homo sapiens 16240 R-HSA-965079 https://reactome.org/PathwayBrowser/#/R-HSA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP TAS Homo sapiens 16240 R-HSA-9698408 https://reactome.org/PathwayBrowser/#/R-HSA-9698408 PTPRJ dephosphorylates active FLT3 TAS Homo sapiens 16240 R-HSA-9698758 https://reactome.org/PathwayBrowser/#/R-HSA-9698758 FLT3 ITD- and NOX4-dependent H2O2 production TAS Homo sapiens 16240 R-HSA-9707504 https://reactome.org/PathwayBrowser/#/R-HSA-9707504 H2O2 oxidises ferrohemoglobin to MetHb TAS Homo sapiens 16240 R-HSA-9709360 https://reactome.org/PathwayBrowser/#/R-HSA-9709360 H2O2 reduces MetHb TAS Homo sapiens 16240 R-HSA-9817575 https://reactome.org/PathwayBrowser/#/R-HSA-9817575 ERO1B oxidizes P4HB TAS Homo sapiens 16240 R-HSA-9854368 https://reactome.org/PathwayBrowser/#/R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S TAS Homo sapiens 16240 R-HSA-9861595 https://reactome.org/PathwayBrowser/#/R-HSA-9861595 Cytosolic H2O2 decarboxylates PYR to acetate TAS Homo sapiens 16240 R-HSA-9861745 https://reactome.org/PathwayBrowser/#/R-HSA-9861745 Mitochondrial H2O2 decarboxylates PYR to acetate TAS Homo sapiens 16240 R-MMU-141186 https://reactome.org/PathwayBrowser/#/R-MMU-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Mus musculus 16240 R-MMU-141200 https://reactome.org/PathwayBrowser/#/R-MMU-141200 MAOB:FAD oxidatively deaminates of PEA IEA Mus musculus 16240 R-MMU-141202 https://reactome.org/PathwayBrowser/#/R-MMU-141202 MAOB:FAD oxidatively deaminates TYR IEA Mus musculus 16240 R-MMU-141341 https://reactome.org/PathwayBrowser/#/R-MMU-141341 SMOX-3 oxidises SPN to SPM IEA Mus musculus 16240 R-MMU-141348 https://reactome.org/PathwayBrowser/#/R-MMU-141348 PAO:FAD oxidises NASPM to PTCN IEA Mus musculus 16240 R-MMU-141351 https://reactome.org/PathwayBrowser/#/R-MMU-141351 PAOX:FAD oxidises NASPN to SPM IEA Mus musculus 16240 R-MMU-1614544 https://reactome.org/PathwayBrowser/#/R-MMU-1614544 Sulfite is oxidized to sulfate IEA Mus musculus 16240 R-MMU-189423 https://reactome.org/PathwayBrowser/#/R-MMU-189423 PPO oxidises PPGEN9 to PRIN9 IEA Mus musculus 16240 R-MMU-192335 https://reactome.org/PathwayBrowser/#/R-MMU-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Mus musculus 16240 R-MMU-193369 https://reactome.org/PathwayBrowser/#/R-MMU-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Mus musculus 16240 R-MMU-2002466 https://reactome.org/PathwayBrowser/#/R-MMU-2002466 Formation of allysine by LOX IEA Mus musculus 16240 R-MMU-2066787 https://reactome.org/PathwayBrowser/#/R-MMU-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Mus musculus 16240 R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 16240 R-MMU-2160492 https://reactome.org/PathwayBrowser/#/R-MMU-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Mus musculus 16240 R-MMU-2395340 https://reactome.org/PathwayBrowser/#/R-MMU-2395340 Formation of hydroxyallysine by LOX IEA Mus musculus 16240 R-MMU-2559639 https://reactome.org/PathwayBrowser/#/R-MMU-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Mus musculus 16240 R-MMU-3204311 https://reactome.org/PathwayBrowser/#/R-MMU-3204311 AOX1 oxidises PXL to PDXate IEA Mus musculus 16240 R-MMU-3299680 https://reactome.org/PathwayBrowser/#/R-MMU-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Mus musculus 16240 R-MMU-3299682 https://reactome.org/PathwayBrowser/#/R-MMU-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Mus musculus 16240 R-MMU-3299691 https://reactome.org/PathwayBrowser/#/R-MMU-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Mus musculus 16240 R-MMU-3322995 https://reactome.org/PathwayBrowser/#/R-MMU-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Mus musculus 16240 R-MMU-3323013 https://reactome.org/PathwayBrowser/#/R-MMU-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 16240 R-MMU-3341277 https://reactome.org/PathwayBrowser/#/R-MMU-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 16240 R-MMU-3341296 https://reactome.org/PathwayBrowser/#/R-MMU-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Mus musculus 16240 R-MMU-3341343 https://reactome.org/PathwayBrowser/#/R-MMU-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Mus musculus 16240 R-MMU-3341397 https://reactome.org/PathwayBrowser/#/R-MMU-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 16240 R-MMU-3343700 https://reactome.org/PathwayBrowser/#/R-MMU-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 16240 R-MMU-350901 https://reactome.org/PathwayBrowser/#/R-MMU-350901 Iodide is organified IEA Mus musculus 16240 R-MMU-374909 https://reactome.org/PathwayBrowser/#/R-MMU-374909 Catabolism of Noradrenaline IEA Mus musculus 16240 R-MMU-3777112 https://reactome.org/PathwayBrowser/#/R-MMU-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Mus musculus 16240 R-MMU-379382 https://reactome.org/PathwayBrowser/#/R-MMU-379382 MAOA:FAD deaminates DA to DOPAC IEA Mus musculus 16240 R-MMU-379395 https://reactome.org/PathwayBrowser/#/R-MMU-379395 MAOA:FAD deaminates 3MT to HVA IEA Mus musculus 16240 R-MMU-389821 https://reactome.org/PathwayBrowser/#/R-MMU-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Mus musculus 16240 R-MMU-389842 https://reactome.org/PathwayBrowser/#/R-MMU-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Mus musculus 16240 R-MMU-389862 https://reactome.org/PathwayBrowser/#/R-MMU-389862 Conversion of glyoxylate to oxalate IEA Mus musculus 16240 R-MMU-389889 https://reactome.org/PathwayBrowser/#/R-MMU-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Mus musculus 16240 R-MMU-389891 https://reactome.org/PathwayBrowser/#/R-MMU-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Mus musculus 16240 R-MMU-390256 https://reactome.org/PathwayBrowser/#/R-MMU-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Mus musculus 16240 R-MMU-5631885 https://reactome.org/PathwayBrowser/#/R-MMU-5631885 PRDX1 overoxidizes IEA Mus musculus 16240 R-MMU-5693681 https://reactome.org/PathwayBrowser/#/R-MMU-5693681 DUOX1,2 reduce O2 to H2O2 IEA Mus musculus 16240 R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 16240 R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 16240 R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 16240 R-MMU-6783880 https://reactome.org/PathwayBrowser/#/R-MMU-6783880 PIPOX oxidises PPCA to P6C IEA Mus musculus 16240 R-MMU-6787811 https://reactome.org/PathwayBrowser/#/R-MMU-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Mus musculus 16240 R-MMU-6789031 https://reactome.org/PathwayBrowser/#/R-MMU-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 16240 R-MMU-6789126 https://reactome.org/PathwayBrowser/#/R-MMU-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 16240 R-MMU-6799695 https://reactome.org/PathwayBrowser/#/R-MMU-6799695 GPX5,6 reduce H2O2 to H2O IEA Mus musculus 16240 R-MMU-6810076 https://reactome.org/PathwayBrowser/#/R-MMU-6810076 DDO oxidizes D-Asp to OA IEA Mus musculus 16240 R-MMU-71676 https://reactome.org/PathwayBrowser/#/R-MMU-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Mus musculus 16240 R-MMU-74247 https://reactome.org/PathwayBrowser/#/R-MMU-74247 XDH oxidizes hypoxanthine to form xanthine IEA Mus musculus 16240 R-MMU-74258 https://reactome.org/PathwayBrowser/#/R-MMU-74258 XDH oxidizes xanthine to form urate IEA Mus musculus 16240 R-MMU-76031 https://reactome.org/PathwayBrowser/#/R-MMU-76031 2 H2O2 => O2 + 2 H2O IEA Mus musculus 16240 R-MMU-8855490 https://reactome.org/PathwayBrowser/#/R-MMU-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Mus musculus 16240 R-MMU-8933635 https://reactome.org/PathwayBrowser/#/R-MMU-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Mus musculus 16240 R-MMU-8956458 https://reactome.org/PathwayBrowser/#/R-MMU-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Mus musculus 16240 R-MMU-965019 https://reactome.org/PathwayBrowser/#/R-MMU-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Mus musculus 16240 R-MMU-965079 https://reactome.org/PathwayBrowser/#/R-MMU-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Mus musculus 16240 R-MMU-9698408 https://reactome.org/PathwayBrowser/#/R-MMU-9698408 PTPRJ dephosphorylates active FLT3 IEA Mus musculus 16240 R-MMU-9707504 https://reactome.org/PathwayBrowser/#/R-MMU-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Mus musculus 16240 R-MMU-9709360 https://reactome.org/PathwayBrowser/#/R-MMU-9709360 H2O2 reduces MetHb IEA Mus musculus 16240 R-MMU-9817575 https://reactome.org/PathwayBrowser/#/R-MMU-9817575 ERO1B oxidizes P4HB IEA Mus musculus 16240 R-MMU-9854368 https://reactome.org/PathwayBrowser/#/R-MMU-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Mus musculus 16240 R-PFA-189423 https://reactome.org/PathwayBrowser/#/R-PFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Plasmodium falciparum 16240 R-PFA-2160492 https://reactome.org/PathwayBrowser/#/R-PFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Plasmodium falciparum 16240 R-PFA-3341296 https://reactome.org/PathwayBrowser/#/R-PFA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Plasmodium falciparum 16240 R-PFA-3341343 https://reactome.org/PathwayBrowser/#/R-PFA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Plasmodium falciparum 16240 R-PFA-3343700 https://reactome.org/PathwayBrowser/#/R-PFA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Plasmodium falciparum 16240 R-PFA-9817575 https://reactome.org/PathwayBrowser/#/R-PFA-9817575 ERO1B oxidizes P4HB IEA Plasmodium falciparum 16240 R-RNO-141186 https://reactome.org/PathwayBrowser/#/R-RNO-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Rattus norvegicus 16240 R-RNO-141200 https://reactome.org/PathwayBrowser/#/R-RNO-141200 MAOB:FAD oxidatively deaminates of PEA IEA Rattus norvegicus 16240 R-RNO-141202 https://reactome.org/PathwayBrowser/#/R-RNO-141202 MAOB:FAD oxidatively deaminates TYR IEA Rattus norvegicus 16240 R-RNO-141341 https://reactome.org/PathwayBrowser/#/R-RNO-141341 SMOX-3 oxidises SPN to SPM IEA Rattus norvegicus 16240 R-RNO-141348 https://reactome.org/PathwayBrowser/#/R-RNO-141348 PAO:FAD oxidises NASPM to PTCN IEA Rattus norvegicus 16240 R-RNO-141351 https://reactome.org/PathwayBrowser/#/R-RNO-141351 PAOX:FAD oxidises NASPN to SPM IEA Rattus norvegicus 16240 R-RNO-1614544 https://reactome.org/PathwayBrowser/#/R-RNO-1614544 Sulfite is oxidized to sulfate IEA Rattus norvegicus 16240 R-RNO-189423 https://reactome.org/PathwayBrowser/#/R-RNO-189423 PPO oxidises PPGEN9 to PRIN9 IEA Rattus norvegicus 16240 R-RNO-192335 https://reactome.org/PathwayBrowser/#/R-RNO-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Rattus norvegicus 16240 R-RNO-193369 https://reactome.org/PathwayBrowser/#/R-RNO-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Rattus norvegicus 16240 R-RNO-2002466 https://reactome.org/PathwayBrowser/#/R-RNO-2002466 Formation of allysine by LOX IEA Rattus norvegicus 16240 R-RNO-2066787 https://reactome.org/PathwayBrowser/#/R-RNO-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Rattus norvegicus 16240 R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 16240 R-RNO-2160492 https://reactome.org/PathwayBrowser/#/R-RNO-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Rattus norvegicus 16240 R-RNO-2395340 https://reactome.org/PathwayBrowser/#/R-RNO-2395340 Formation of hydroxyallysine by LOX IEA Rattus norvegicus 16240 R-RNO-2559639 https://reactome.org/PathwayBrowser/#/R-RNO-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Rattus norvegicus 16240 R-RNO-3204311 https://reactome.org/PathwayBrowser/#/R-RNO-3204311 AOX1 oxidises PXL to PDXate IEA Rattus norvegicus 16240 R-RNO-3299680 https://reactome.org/PathwayBrowser/#/R-RNO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Rattus norvegicus 16240 R-RNO-3299682 https://reactome.org/PathwayBrowser/#/R-RNO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Rattus norvegicus 16240 R-RNO-3299691 https://reactome.org/PathwayBrowser/#/R-RNO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Rattus norvegicus 16240 R-RNO-3322995 https://reactome.org/PathwayBrowser/#/R-RNO-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Rattus norvegicus 16240 R-RNO-3323013 https://reactome.org/PathwayBrowser/#/R-RNO-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 16240 R-RNO-3341277 https://reactome.org/PathwayBrowser/#/R-RNO-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 16240 R-RNO-3341296 https://reactome.org/PathwayBrowser/#/R-RNO-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Rattus norvegicus 16240 R-RNO-3341343 https://reactome.org/PathwayBrowser/#/R-RNO-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Rattus norvegicus 16240 R-RNO-3341397 https://reactome.org/PathwayBrowser/#/R-RNO-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 16240 R-RNO-3343700 https://reactome.org/PathwayBrowser/#/R-RNO-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 16240 R-RNO-350901 https://reactome.org/PathwayBrowser/#/R-RNO-350901 Iodide is organified IEA Rattus norvegicus 16240 R-RNO-374909 https://reactome.org/PathwayBrowser/#/R-RNO-374909 Catabolism of Noradrenaline IEA Rattus norvegicus 16240 R-RNO-3777112 https://reactome.org/PathwayBrowser/#/R-RNO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Rattus norvegicus 16240 R-RNO-3779389 https://reactome.org/PathwayBrowser/#/R-RNO-3779389 H2O2 diffuses from the mitochondrial matrix to the cytosol TAS Rattus norvegicus 16240 R-RNO-379382 https://reactome.org/PathwayBrowser/#/R-RNO-379382 MAOA:FAD deaminates DA to DOPAC IEA Rattus norvegicus 16240 R-RNO-379395 https://reactome.org/PathwayBrowser/#/R-RNO-379395 MAOA:FAD deaminates 3MT to HVA IEA Rattus norvegicus 16240 R-RNO-389821 https://reactome.org/PathwayBrowser/#/R-RNO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Rattus norvegicus 16240 R-RNO-389842 https://reactome.org/PathwayBrowser/#/R-RNO-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Rattus norvegicus 16240 R-RNO-389862 https://reactome.org/PathwayBrowser/#/R-RNO-389862 Conversion of glyoxylate to oxalate IEA Rattus norvegicus 16240 R-RNO-389889 https://reactome.org/PathwayBrowser/#/R-RNO-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Rattus norvegicus 16240 R-RNO-389891 https://reactome.org/PathwayBrowser/#/R-RNO-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Rattus norvegicus 16240 R-RNO-390256 https://reactome.org/PathwayBrowser/#/R-RNO-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Rattus norvegicus 16240 R-RNO-5631885 https://reactome.org/PathwayBrowser/#/R-RNO-5631885 PRDX1 overoxidizes IEA Rattus norvegicus 16240 R-RNO-5693681 https://reactome.org/PathwayBrowser/#/R-RNO-5693681 DUOX1,2 reduce O2 to H2O2 IEA Rattus norvegicus 16240 R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 16240 R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 16240 R-RNO-6783880 https://reactome.org/PathwayBrowser/#/R-RNO-6783880 PIPOX oxidises PPCA to P6C IEA Rattus norvegicus 16240 R-RNO-6787811 https://reactome.org/PathwayBrowser/#/R-RNO-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Rattus norvegicus 16240 R-RNO-6789031 https://reactome.org/PathwayBrowser/#/R-RNO-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 16240 R-RNO-6789126 https://reactome.org/PathwayBrowser/#/R-RNO-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 16240 R-RNO-6799695 https://reactome.org/PathwayBrowser/#/R-RNO-6799695 GPX5,6 reduce H2O2 to H2O IEA Rattus norvegicus 16240 R-RNO-6810076 https://reactome.org/PathwayBrowser/#/R-RNO-6810076 DDO oxidizes D-Asp to OA IEA Rattus norvegicus 16240 R-RNO-71676 https://reactome.org/PathwayBrowser/#/R-RNO-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Rattus norvegicus 16240 R-RNO-74247 https://reactome.org/PathwayBrowser/#/R-RNO-74247 XDH oxidizes hypoxanthine to form xanthine IEA Rattus norvegicus 16240 R-RNO-74258 https://reactome.org/PathwayBrowser/#/R-RNO-74258 XDH oxidizes xanthine to form urate IEA Rattus norvegicus 16240 R-RNO-76031 https://reactome.org/PathwayBrowser/#/R-RNO-76031 2 H2O2 => O2 + 2 H2O IEA Rattus norvegicus 16240 R-RNO-8855490 https://reactome.org/PathwayBrowser/#/R-RNO-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Rattus norvegicus 16240 R-RNO-8933635 https://reactome.org/PathwayBrowser/#/R-RNO-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Rattus norvegicus 16240 R-RNO-8956458 https://reactome.org/PathwayBrowser/#/R-RNO-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Rattus norvegicus 16240 R-RNO-965019 https://reactome.org/PathwayBrowser/#/R-RNO-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Rattus norvegicus 16240 R-RNO-965079 https://reactome.org/PathwayBrowser/#/R-RNO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Rattus norvegicus 16240 R-RNO-9707504 https://reactome.org/PathwayBrowser/#/R-RNO-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Rattus norvegicus 16240 R-RNO-9709360 https://reactome.org/PathwayBrowser/#/R-RNO-9709360 H2O2 reduces MetHb IEA Rattus norvegicus 16240 R-RNO-9817575 https://reactome.org/PathwayBrowser/#/R-RNO-9817575 ERO1B oxidizes P4HB IEA Rattus norvegicus 16240 R-RNO-9854368 https://reactome.org/PathwayBrowser/#/R-RNO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Rattus norvegicus 16240 R-SCE-189423 https://reactome.org/PathwayBrowser/#/R-SCE-189423 PPO oxidises PPGEN9 to PRIN9 IEA Saccharomyces cerevisiae 16240 R-SCE-3299680 https://reactome.org/PathwayBrowser/#/R-SCE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Saccharomyces cerevisiae 16240 R-SCE-3299682 https://reactome.org/PathwayBrowser/#/R-SCE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Saccharomyces cerevisiae 16240 R-SCE-3299691 https://reactome.org/PathwayBrowser/#/R-SCE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Saccharomyces cerevisiae 16240 R-SCE-3341343 https://reactome.org/PathwayBrowser/#/R-SCE-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Saccharomyces cerevisiae 16240 R-SCE-3777112 https://reactome.org/PathwayBrowser/#/R-SCE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Saccharomyces cerevisiae 16240 R-SCE-389891 https://reactome.org/PathwayBrowser/#/R-SCE-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Saccharomyces cerevisiae 16240 R-SCE-5631885 https://reactome.org/PathwayBrowser/#/R-SCE-5631885 PRDX1 overoxidizes IEA Saccharomyces cerevisiae 16240 R-SCE-5693681 https://reactome.org/PathwayBrowser/#/R-SCE-5693681 DUOX1,2 reduce O2 to H2O2 IEA Saccharomyces cerevisiae 16240 R-SCE-76031 https://reactome.org/PathwayBrowser/#/R-SCE-76031 2 H2O2 => O2 + 2 H2O IEA Saccharomyces cerevisiae 16240 R-SCE-965019 https://reactome.org/PathwayBrowser/#/R-SCE-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Saccharomyces cerevisiae 16240 R-SCE-965079 https://reactome.org/PathwayBrowser/#/R-SCE-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Saccharomyces cerevisiae 16240 R-SCE-9854368 https://reactome.org/PathwayBrowser/#/R-SCE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Saccharomyces cerevisiae 16240 R-SPO-189423 https://reactome.org/PathwayBrowser/#/R-SPO-189423 PPO oxidises PPGEN9 to PRIN9 IEA Schizosaccharomyces pombe 16240 R-SPO-3299680 https://reactome.org/PathwayBrowser/#/R-SPO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Schizosaccharomyces pombe 16240 R-SPO-3299682 https://reactome.org/PathwayBrowser/#/R-SPO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Schizosaccharomyces pombe 16240 R-SPO-3299691 https://reactome.org/PathwayBrowser/#/R-SPO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Schizosaccharomyces pombe 16240 R-SPO-3341343 https://reactome.org/PathwayBrowser/#/R-SPO-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Schizosaccharomyces pombe 16240 R-SPO-3777112 https://reactome.org/PathwayBrowser/#/R-SPO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Schizosaccharomyces pombe 16240 R-SPO-389821 https://reactome.org/PathwayBrowser/#/R-SPO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Schizosaccharomyces pombe 16240 R-SPO-5631885 https://reactome.org/PathwayBrowser/#/R-SPO-5631885 PRDX1 overoxidizes IEA Schizosaccharomyces pombe 16240 R-SPO-6783880 https://reactome.org/PathwayBrowser/#/R-SPO-6783880 PIPOX oxidises PPCA to P6C IEA Schizosaccharomyces pombe 16240 R-SPO-6810076 https://reactome.org/PathwayBrowser/#/R-SPO-6810076 DDO oxidizes D-Asp to OA IEA Schizosaccharomyces pombe 16240 R-SPO-76031 https://reactome.org/PathwayBrowser/#/R-SPO-76031 2 H2O2 => O2 + 2 H2O IEA Schizosaccharomyces pombe 16240 R-SPO-965019 https://reactome.org/PathwayBrowser/#/R-SPO-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Schizosaccharomyces pombe 16240 R-SPO-965079 https://reactome.org/PathwayBrowser/#/R-SPO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Schizosaccharomyces pombe 16240 R-SPO-9854368 https://reactome.org/PathwayBrowser/#/R-SPO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Schizosaccharomyces pombe 16240 R-SSC-141186 https://reactome.org/PathwayBrowser/#/R-SSC-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Sus scrofa 16240 R-SSC-141200 https://reactome.org/PathwayBrowser/#/R-SSC-141200 MAOB:FAD oxidatively deaminates of PEA IEA Sus scrofa 16240 R-SSC-141202 https://reactome.org/PathwayBrowser/#/R-SSC-141202 MAOB:FAD oxidatively deaminates TYR IEA Sus scrofa 16240 R-SSC-141341 https://reactome.org/PathwayBrowser/#/R-SSC-141341 SMOX-3 oxidises SPN to SPM IEA Sus scrofa 16240 R-SSC-141348 https://reactome.org/PathwayBrowser/#/R-SSC-141348 PAO:FAD oxidises NASPM to PTCN IEA Sus scrofa 16240 R-SSC-141351 https://reactome.org/PathwayBrowser/#/R-SSC-141351 PAOX:FAD oxidises NASPN to SPM IEA Sus scrofa 16240 R-SSC-1614544 https://reactome.org/PathwayBrowser/#/R-SSC-1614544 Sulfite is oxidized to sulfate IEA Sus scrofa 16240 R-SSC-189423 https://reactome.org/PathwayBrowser/#/R-SSC-189423 PPO oxidises PPGEN9 to PRIN9 IEA Sus scrofa 16240 R-SSC-192335 https://reactome.org/PathwayBrowser/#/R-SSC-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Sus scrofa 16240 R-SSC-193369 https://reactome.org/PathwayBrowser/#/R-SSC-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Sus scrofa 16240 R-SSC-2002466 https://reactome.org/PathwayBrowser/#/R-SSC-2002466 Formation of allysine by LOX IEA Sus scrofa 16240 R-SSC-2066787 https://reactome.org/PathwayBrowser/#/R-SSC-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Sus scrofa 16240 R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 16240 R-SSC-2160492 https://reactome.org/PathwayBrowser/#/R-SSC-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Sus scrofa 16240 R-SSC-2395340 https://reactome.org/PathwayBrowser/#/R-SSC-2395340 Formation of hydroxyallysine by LOX IEA Sus scrofa 16240 R-SSC-2559639 https://reactome.org/PathwayBrowser/#/R-SSC-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Sus scrofa 16240 R-SSC-3204311 https://reactome.org/PathwayBrowser/#/R-SSC-3204311 AOX1 oxidises PXL to PDXate IEA Sus scrofa 16240 R-SSC-3299680 https://reactome.org/PathwayBrowser/#/R-SSC-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Sus scrofa 16240 R-SSC-3299682 https://reactome.org/PathwayBrowser/#/R-SSC-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Sus scrofa 16240 R-SSC-3299691 https://reactome.org/PathwayBrowser/#/R-SSC-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Sus scrofa 16240 R-SSC-3322995 https://reactome.org/PathwayBrowser/#/R-SSC-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Sus scrofa 16240 R-SSC-3323013 https://reactome.org/PathwayBrowser/#/R-SSC-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 16240 R-SSC-3341277 https://reactome.org/PathwayBrowser/#/R-SSC-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 16240 R-SSC-3341296 https://reactome.org/PathwayBrowser/#/R-SSC-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Sus scrofa 16240 R-SSC-3341343 https://reactome.org/PathwayBrowser/#/R-SSC-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Sus scrofa 16240 R-SSC-3341397 https://reactome.org/PathwayBrowser/#/R-SSC-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 16240 R-SSC-3343700 https://reactome.org/PathwayBrowser/#/R-SSC-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 16240 R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa 16240 R-SSC-374909 https://reactome.org/PathwayBrowser/#/R-SSC-374909 Catabolism of Noradrenaline IEA Sus scrofa 16240 R-SSC-3777112 https://reactome.org/PathwayBrowser/#/R-SSC-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Sus scrofa 16240 R-SSC-379382 https://reactome.org/PathwayBrowser/#/R-SSC-379382 MAOA:FAD deaminates DA to DOPAC IEA Sus scrofa 16240 R-SSC-379395 https://reactome.org/PathwayBrowser/#/R-SSC-379395 MAOA:FAD deaminates 3MT to HVA IEA Sus scrofa 16240 R-SSC-389821 https://reactome.org/PathwayBrowser/#/R-SSC-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Sus scrofa 16240 R-SSC-389842 https://reactome.org/PathwayBrowser/#/R-SSC-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Sus scrofa 16240 R-SSC-389862 https://reactome.org/PathwayBrowser/#/R-SSC-389862 Conversion of glyoxylate to oxalate IEA Sus scrofa 16240 R-SSC-389889 https://reactome.org/PathwayBrowser/#/R-SSC-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Sus scrofa 16240 R-SSC-389891 https://reactome.org/PathwayBrowser/#/R-SSC-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Sus scrofa 16240 R-SSC-390256 https://reactome.org/PathwayBrowser/#/R-SSC-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Sus scrofa 16240 R-SSC-5631885 https://reactome.org/PathwayBrowser/#/R-SSC-5631885 PRDX1 overoxidizes IEA Sus scrofa 16240 R-SSC-5693681 https://reactome.org/PathwayBrowser/#/R-SSC-5693681 DUOX1,2 reduce O2 to H2O2 IEA Sus scrofa 16240 R-SSC-5696131 https://reactome.org/PathwayBrowser/#/R-SSC-5696131 AOC1 deaminates Hist IEA Sus scrofa 16240 R-SSC-5696146 https://reactome.org/PathwayBrowser/#/R-SSC-5696146 AOC2 deaminates TYR IEA Sus scrofa 16240 R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa 16240 R-SSC-6783880 https://reactome.org/PathwayBrowser/#/R-SSC-6783880 PIPOX oxidises PPCA to P6C IEA Sus scrofa 16240 R-SSC-6787811 https://reactome.org/PathwayBrowser/#/R-SSC-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Sus scrofa 16240 R-SSC-6789031 https://reactome.org/PathwayBrowser/#/R-SSC-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 16240 R-SSC-6789126 https://reactome.org/PathwayBrowser/#/R-SSC-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 16240 R-SSC-6799695 https://reactome.org/PathwayBrowser/#/R-SSC-6799695 GPX5,6 reduce H2O2 to H2O IEA Sus scrofa 16240 R-SSC-6810076 https://reactome.org/PathwayBrowser/#/R-SSC-6810076 DDO oxidizes D-Asp to OA IEA Sus scrofa 16240 R-SSC-71676 https://reactome.org/PathwayBrowser/#/R-SSC-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Sus scrofa 16240 R-SSC-74247 https://reactome.org/PathwayBrowser/#/R-SSC-74247 XDH oxidizes hypoxanthine to form xanthine IEA Sus scrofa 16240 R-SSC-74258 https://reactome.org/PathwayBrowser/#/R-SSC-74258 XDH oxidizes xanthine to form urate IEA Sus scrofa 16240 R-SSC-76031 https://reactome.org/PathwayBrowser/#/R-SSC-76031 2 H2O2 => O2 + 2 H2O IEA Sus scrofa 16240 R-SSC-8855490 https://reactome.org/PathwayBrowser/#/R-SSC-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Sus scrofa 16240 R-SSC-8865107 https://reactome.org/PathwayBrowser/#/R-SSC-8865107 MICAL1 produces NADP+, H2O2 IEA Sus scrofa 16240 R-SSC-8933635 https://reactome.org/PathwayBrowser/#/R-SSC-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Sus scrofa 16240 R-SSC-8956458 https://reactome.org/PathwayBrowser/#/R-SSC-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Sus scrofa 16240 R-SSC-965019 https://reactome.org/PathwayBrowser/#/R-SSC-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Sus scrofa 16240 R-SSC-965079 https://reactome.org/PathwayBrowser/#/R-SSC-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Sus scrofa 16240 R-SSC-9707504 https://reactome.org/PathwayBrowser/#/R-SSC-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Sus scrofa 16240 R-SSC-9709360 https://reactome.org/PathwayBrowser/#/R-SSC-9709360 H2O2 reduces MetHb IEA Sus scrofa 16240 R-SSC-9817575 https://reactome.org/PathwayBrowser/#/R-SSC-9817575 ERO1B oxidizes P4HB IEA Sus scrofa 16240 R-SSC-9854368 https://reactome.org/PathwayBrowser/#/R-SSC-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Sus scrofa 16240 R-XTR-141200 https://reactome.org/PathwayBrowser/#/R-XTR-141200 MAOB:FAD oxidatively deaminates of PEA IEA Xenopus tropicalis 16240 R-XTR-141202 https://reactome.org/PathwayBrowser/#/R-XTR-141202 MAOB:FAD oxidatively deaminates TYR IEA Xenopus tropicalis 16240 R-XTR-141341 https://reactome.org/PathwayBrowser/#/R-XTR-141341 SMOX-3 oxidises SPN to SPM IEA Xenopus tropicalis 16240 R-XTR-1614544 https://reactome.org/PathwayBrowser/#/R-XTR-1614544 Sulfite is oxidized to sulfate IEA Xenopus tropicalis 16240 R-XTR-189423 https://reactome.org/PathwayBrowser/#/R-XTR-189423 PPO oxidises PPGEN9 to PRIN9 IEA Xenopus tropicalis 16240 R-XTR-192335 https://reactome.org/PathwayBrowser/#/R-XTR-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Xenopus tropicalis 16240 R-XTR-193369 https://reactome.org/PathwayBrowser/#/R-XTR-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Xenopus tropicalis 16240 R-XTR-2002466 https://reactome.org/PathwayBrowser/#/R-XTR-2002466 Formation of allysine by LOX IEA Xenopus tropicalis 16240 R-XTR-2066787 https://reactome.org/PathwayBrowser/#/R-XTR-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Xenopus tropicalis 16240 R-XTR-2160492 https://reactome.org/PathwayBrowser/#/R-XTR-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Xenopus tropicalis 16240 R-XTR-2395340 https://reactome.org/PathwayBrowser/#/R-XTR-2395340 Formation of hydroxyallysine by LOX IEA Xenopus tropicalis 16240 R-XTR-2559639 https://reactome.org/PathwayBrowser/#/R-XTR-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Xenopus tropicalis 16240 R-XTR-3204311 https://reactome.org/PathwayBrowser/#/R-XTR-3204311 AOX1 oxidises PXL to PDXate IEA Xenopus tropicalis 16240 R-XTR-3299680 https://reactome.org/PathwayBrowser/#/R-XTR-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Xenopus tropicalis 16240 R-XTR-3299682 https://reactome.org/PathwayBrowser/#/R-XTR-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Xenopus tropicalis 16240 R-XTR-3299691 https://reactome.org/PathwayBrowser/#/R-XTR-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Xenopus tropicalis 16240 R-XTR-3322995 https://reactome.org/PathwayBrowser/#/R-XTR-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Xenopus tropicalis 16240 R-XTR-3341296 https://reactome.org/PathwayBrowser/#/R-XTR-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Xenopus tropicalis 16240 R-XTR-3343700 https://reactome.org/PathwayBrowser/#/R-XTR-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Xenopus tropicalis 16240 R-XTR-3777112 https://reactome.org/PathwayBrowser/#/R-XTR-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Xenopus tropicalis 16240 R-XTR-389821 https://reactome.org/PathwayBrowser/#/R-XTR-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Xenopus tropicalis 16240 R-XTR-389842 https://reactome.org/PathwayBrowser/#/R-XTR-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Xenopus tropicalis 16240 R-XTR-389862 https://reactome.org/PathwayBrowser/#/R-XTR-389862 Conversion of glyoxylate to oxalate IEA Xenopus tropicalis 16240 R-XTR-389889 https://reactome.org/PathwayBrowser/#/R-XTR-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Xenopus tropicalis 16240 R-XTR-389891 https://reactome.org/PathwayBrowser/#/R-XTR-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Xenopus tropicalis 16240 R-XTR-390256 https://reactome.org/PathwayBrowser/#/R-XTR-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Xenopus tropicalis 16240 R-XTR-5631885 https://reactome.org/PathwayBrowser/#/R-XTR-5631885 PRDX1 overoxidizes IEA Xenopus tropicalis 16240 R-XTR-5693681 https://reactome.org/PathwayBrowser/#/R-XTR-5693681 DUOX1,2 reduce O2 to H2O2 IEA Xenopus tropicalis 16240 R-XTR-5696131 https://reactome.org/PathwayBrowser/#/R-XTR-5696131 AOC1 deaminates Hist IEA Xenopus tropicalis 16240 R-XTR-5696183 https://reactome.org/PathwayBrowser/#/R-XTR-5696183 AOC3 deaminates BZAM IEA Xenopus tropicalis 16240 R-XTR-6783880 https://reactome.org/PathwayBrowser/#/R-XTR-6783880 PIPOX oxidises PPCA to P6C IEA Xenopus tropicalis 16240 R-XTR-6787811 https://reactome.org/PathwayBrowser/#/R-XTR-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Xenopus tropicalis 16240 R-XTR-74247 https://reactome.org/PathwayBrowser/#/R-XTR-74247 XDH oxidizes hypoxanthine to form xanthine IEA Xenopus tropicalis 16240 R-XTR-74258 https://reactome.org/PathwayBrowser/#/R-XTR-74258 XDH oxidizes xanthine to form urate IEA Xenopus tropicalis 16240 R-XTR-76031 https://reactome.org/PathwayBrowser/#/R-XTR-76031 2 H2O2 => O2 + 2 H2O IEA Xenopus tropicalis 16240 R-XTR-8865107 https://reactome.org/PathwayBrowser/#/R-XTR-8865107 MICAL1 produces NADP+, H2O2 IEA Xenopus tropicalis 16240 R-XTR-8956458 https://reactome.org/PathwayBrowser/#/R-XTR-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Xenopus tropicalis 16240 R-XTR-965019 https://reactome.org/PathwayBrowser/#/R-XTR-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Xenopus tropicalis 16240 R-XTR-965079 https://reactome.org/PathwayBrowser/#/R-XTR-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Xenopus tropicalis 16240 R-XTR-9707504 https://reactome.org/PathwayBrowser/#/R-XTR-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Xenopus tropicalis 16240 R-XTR-9709360 https://reactome.org/PathwayBrowser/#/R-XTR-9709360 H2O2 reduces MetHb IEA Xenopus tropicalis 16240 R-XTR-9817575 https://reactome.org/PathwayBrowser/#/R-XTR-9817575 ERO1B oxidizes P4HB IEA Xenopus tropicalis 16240 R-XTR-9854368 https://reactome.org/PathwayBrowser/#/R-XTR-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Xenopus tropicalis 16243 R-BTA-8953398 https://reactome.org/PathwayBrowser/#/R-BTA-8953398 PIR oxygenates quercetin IEA Bos taurus 16243 R-CFA-8953398 https://reactome.org/PathwayBrowser/#/R-CFA-8953398 PIR oxygenates quercetin IEA Canis familiaris 16243 R-DDI-8953398 https://reactome.org/PathwayBrowser/#/R-DDI-8953398 PIR oxygenates quercetin IEA Dictyostelium discoideum 16243 R-HSA-8953398 https://reactome.org/PathwayBrowser/#/R-HSA-8953398 PIR oxygenates quercetin TAS Homo sapiens 16243 R-MMU-8953398 https://reactome.org/PathwayBrowser/#/R-MMU-8953398 PIR oxygenates quercetin IEA Mus musculus 16243 R-RNO-8953398 https://reactome.org/PathwayBrowser/#/R-RNO-8953398 PIR oxygenates quercetin IEA Rattus norvegicus 16243 R-SSC-8953398 https://reactome.org/PathwayBrowser/#/R-SSC-8953398 PIR oxygenates quercetin IEA Sus scrofa 16243 R-XTR-8953398 https://reactome.org/PathwayBrowser/#/R-XTR-8953398 PIR oxygenates quercetin IEA Xenopus tropicalis 16244 R-BTA-71260 https://reactome.org/PathwayBrowser/#/R-BTA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Bos taurus 16244 R-BTA-71261 https://reactome.org/PathwayBrowser/#/R-BTA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Bos taurus 16244 R-CEL-71260 https://reactome.org/PathwayBrowser/#/R-CEL-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Caenorhabditis elegans 16244 R-CEL-71261 https://reactome.org/PathwayBrowser/#/R-CEL-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Caenorhabditis elegans 16244 R-CFA-71260 https://reactome.org/PathwayBrowser/#/R-CFA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Canis familiaris 16244 R-CFA-71261 https://reactome.org/PathwayBrowser/#/R-CFA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Canis familiaris 16244 R-DME-71261 https://reactome.org/PathwayBrowser/#/R-DME-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Drosophila melanogaster 16244 R-DRE-71260 https://reactome.org/PathwayBrowser/#/R-DRE-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Danio rerio 16244 R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio 16244 R-GGA-71260 https://reactome.org/PathwayBrowser/#/R-GGA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Gallus gallus 16244 R-GGA-71261 https://reactome.org/PathwayBrowser/#/R-GGA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Gallus gallus 16244 R-HSA-71260 https://reactome.org/PathwayBrowser/#/R-HSA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT TAS Homo sapiens 16244 R-HSA-71261 https://reactome.org/PathwayBrowser/#/R-HSA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA TAS Homo sapiens 16244 R-MMU-71260 https://reactome.org/PathwayBrowser/#/R-MMU-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Mus musculus 16244 R-MMU-71261 https://reactome.org/PathwayBrowser/#/R-MMU-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Mus musculus 16244 R-RNO-71260 https://reactome.org/PathwayBrowser/#/R-RNO-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Rattus norvegicus 16244 R-RNO-71261 https://reactome.org/PathwayBrowser/#/R-RNO-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Rattus norvegicus 16244 R-SCE-71261 https://reactome.org/PathwayBrowser/#/R-SCE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Saccharomyces cerevisiae 16244 R-SSC-71260 https://reactome.org/PathwayBrowser/#/R-SSC-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Sus scrofa 16244 R-SSC-71261 https://reactome.org/PathwayBrowser/#/R-SSC-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Sus scrofa 16244 R-XTR-71260 https://reactome.org/PathwayBrowser/#/R-XTR-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Xenopus tropicalis 16244 R-XTR-71261 https://reactome.org/PathwayBrowser/#/R-XTR-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Xenopus tropicalis 16247 R-BTA-171059 https://reactome.org/PathwayBrowser/#/R-BTA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Bos taurus 16247 R-BTA-171106 https://reactome.org/PathwayBrowser/#/R-BTA-171106 LDLR:LDL complex => LDLR + LDL IEA Bos taurus 16247 R-BTA-171122 https://reactome.org/PathwayBrowser/#/R-BTA-171122 LDL + LDLR => LDL:LDLR complex IEA Bos taurus 16247 R-BTA-171141 https://reactome.org/PathwayBrowser/#/R-BTA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Bos taurus 16247 R-BTA-174587 https://reactome.org/PathwayBrowser/#/R-BTA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Bos taurus 16247 R-BTA-174657 https://reactome.org/PathwayBrowser/#/R-BTA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Bos taurus 16247 R-BTA-174660 https://reactome.org/PathwayBrowser/#/R-BTA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Bos taurus 16247 R-BTA-174690 https://reactome.org/PathwayBrowser/#/R-BTA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Bos taurus 16247 R-BTA-174706 https://reactome.org/PathwayBrowser/#/R-BTA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Bos taurus 16247 R-BTA-174739 https://reactome.org/PathwayBrowser/#/R-BTA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Bos taurus 16247 R-BTA-174741 https://reactome.org/PathwayBrowser/#/R-BTA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Bos taurus 16247 R-BTA-174757 https://reactome.org/PathwayBrowser/#/R-BTA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Bos taurus 16247 R-BTA-174786 https://reactome.org/PathwayBrowser/#/R-BTA-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Bos taurus 16247 R-BTA-203130 https://reactome.org/PathwayBrowser/#/R-BTA-203130 OLR1 binds to oxidized LDL IEA Bos taurus 16247 R-BTA-216756 https://reactome.org/PathwayBrowser/#/R-BTA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Bos taurus 16247 R-BTA-216757 https://reactome.org/PathwayBrowser/#/R-BTA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Bos taurus 16247 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 16247 R-BTA-2187332 https://reactome.org/PathwayBrowser/#/R-BTA-2187332 Cytosolic CMs translocate to extracellular region IEA Bos taurus 16247 R-BTA-2197646 https://reactome.org/PathwayBrowser/#/R-BTA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Bos taurus 16247 R-BTA-2197770 https://reactome.org/PathwayBrowser/#/R-BTA-2197770 STAB1 (FEEL-1) binds ligands IEA Bos taurus 16247 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 16247 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 16247 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 16247 R-BTA-2247513 https://reactome.org/PathwayBrowser/#/R-BTA-2247513 STAB1:ligand is endocytosed IEA Bos taurus 16247 R-BTA-2395764 https://reactome.org/PathwayBrowser/#/R-BTA-2395764 atREs binds to nascent CM IEA Bos taurus 16247 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 16247 R-BTA-2395784 https://reactome.org/PathwayBrowser/#/R-BTA-2395784 Nascent CMs transform into mature CMs IEA Bos taurus 16247 R-BTA-2404131 https://reactome.org/PathwayBrowser/#/R-BTA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Bos taurus 16247 R-BTA-2423785 https://reactome.org/PathwayBrowser/#/R-BTA-2423785 CR:atREs binds apoE and HSPG IEA Bos taurus 16247 R-BTA-2512800 https://reactome.org/PathwayBrowser/#/R-BTA-2512800 SCARB1:ligand is endocytosed IEA Bos taurus 16247 R-BTA-264678 https://reactome.org/PathwayBrowser/#/R-BTA-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Bos taurus 16247 R-BTA-264689 https://reactome.org/PathwayBrowser/#/R-BTA-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Bos taurus 16247 R-BTA-266089 https://reactome.org/PathwayBrowser/#/R-BTA-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Bos taurus 16247 R-BTA-266299 https://reactome.org/PathwayBrowser/#/R-BTA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Bos taurus 16247 R-BTA-266303 https://reactome.org/PathwayBrowser/#/R-BTA-266303 Spherical HDL binds C and E apolipoproteins IEA Bos taurus 16247 R-BTA-266310 https://reactome.org/PathwayBrowser/#/R-BTA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Bos taurus 16247 R-BTA-266315 https://reactome.org/PathwayBrowser/#/R-BTA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Bos taurus 16247 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 16247 R-BTA-349637 https://reactome.org/PathwayBrowser/#/R-BTA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Bos taurus 16247 R-BTA-349638 https://reactome.org/PathwayBrowser/#/R-BTA-349638 Disassembly of SR-BI-bound spherical HDL IEA Bos taurus 16247 R-BTA-349657 https://reactome.org/PathwayBrowser/#/R-BTA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Bos taurus 16247 R-BTA-432121 https://reactome.org/PathwayBrowser/#/R-BTA-432121 LDL binds to LRP8 IEA Bos taurus 16247 R-BTA-432129 https://reactome.org/PathwayBrowser/#/R-BTA-432129 FGR binds and phosphorylates LRP8 IEA Bos taurus 16247 R-BTA-435244 https://reactome.org/PathwayBrowser/#/R-BTA-435244 PECAM1 is phosphorylated IEA Bos taurus 16247 R-BTA-5333678 https://reactome.org/PathwayBrowser/#/R-BTA-5333678 CPNEs bind PL IEA Bos taurus 16247 R-BTA-8856630 https://reactome.org/PathwayBrowser/#/R-BTA-8856630 CIDEA:CIDEC binds lipid droplets IEA Bos taurus 16247 R-BTA-8858252 https://reactome.org/PathwayBrowser/#/R-BTA-8858252 HDLBP binds HDL IEA Bos taurus 16247 R-BTA-8862380 https://reactome.org/PathwayBrowser/#/R-BTA-8862380 HSD17B13 binds lipid droplets IEA Bos taurus 16247 R-BTA-8863471 https://reactome.org/PathwayBrowser/#/R-BTA-8863471 LDLR is bound by DAB2 and ARH IEA Bos taurus 16247 R-BTA-8865667 https://reactome.org/PathwayBrowser/#/R-BTA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Bos taurus 16247 R-BTA-8866304 https://reactome.org/PathwayBrowser/#/R-BTA-8866304 pre-VLDL binds lipids to form VLDL IEA Bos taurus 16247 R-BTA-8866308 https://reactome.org/PathwayBrowser/#/R-BTA-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Bos taurus 16247 R-BTA-8866327 https://reactome.org/PathwayBrowser/#/R-BTA-8866327 VLDL translocates from SER lumen to extracellular region IEA Bos taurus 16247 R-BTA-8866329 https://reactome.org/PathwayBrowser/#/R-BTA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Bos taurus 16247 R-BTA-8867754 https://reactome.org/PathwayBrowser/#/R-BTA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Bos taurus 16247 R-BTA-8867756 https://reactome.org/PathwayBrowser/#/R-BTA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Bos taurus 16247 R-BTA-8868071 https://reactome.org/PathwayBrowser/#/R-BTA-8868071 Clathrin recruits PIK3C2A IEA Bos taurus 16247 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 16247 R-BTA-8868230 https://reactome.org/PathwayBrowser/#/R-BTA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Bos taurus 16247 R-BTA-8868236 https://reactome.org/PathwayBrowser/#/R-BTA-8868236 BAR domain proteins recruit dynamin IEA Bos taurus 16247 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 16247 R-BTA-8868651 https://reactome.org/PathwayBrowser/#/R-BTA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Bos taurus 16247 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 16247 R-BTA-8868659 https://reactome.org/PathwayBrowser/#/R-BTA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Bos taurus 16247 R-BTA-8868660 https://reactome.org/PathwayBrowser/#/R-BTA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Bos taurus 16247 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 16247 R-BTA-8869667 https://reactome.org/PathwayBrowser/#/R-BTA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Bos taurus 16247 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 16247 R-BTA-8871194 https://reactome.org/PathwayBrowser/#/R-BTA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Bos taurus 16247 R-BTA-8876366 https://reactome.org/PathwayBrowser/#/R-BTA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Bos taurus 16247 R-BTA-8948034 https://reactome.org/PathwayBrowser/#/R-BTA-8948034 FGR binds LDL:LRP8 IEA Bos taurus 16247 R-BTA-9707586 https://reactome.org/PathwayBrowser/#/R-BTA-9707586 FeHM oxidises LDL,HDL IEA Bos taurus 16247 R-BTA-9737780 https://reactome.org/PathwayBrowser/#/R-BTA-9737780 MTTP binds lomitapide IEA Bos taurus 16247 R-CEL-9737780 https://reactome.org/PathwayBrowser/#/R-CEL-9737780 MTTP binds lomitapide IEA Caenorhabditis elegans 16247 R-CFA-171059 https://reactome.org/PathwayBrowser/#/R-CFA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Canis familiaris 16247 R-CFA-171106 https://reactome.org/PathwayBrowser/#/R-CFA-171106 LDLR:LDL complex => LDLR + LDL IEA Canis familiaris 16247 R-CFA-171122 https://reactome.org/PathwayBrowser/#/R-CFA-171122 LDL + LDLR => LDL:LDLR complex IEA Canis familiaris 16247 R-CFA-171141 https://reactome.org/PathwayBrowser/#/R-CFA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Canis familiaris 16247 R-CFA-174587 https://reactome.org/PathwayBrowser/#/R-CFA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Canis familiaris 16247 R-CFA-174657 https://reactome.org/PathwayBrowser/#/R-CFA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Canis familiaris 16247 R-CFA-174660 https://reactome.org/PathwayBrowser/#/R-CFA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Canis familiaris 16247 R-CFA-174690 https://reactome.org/PathwayBrowser/#/R-CFA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Canis familiaris 16247 R-CFA-174706 https://reactome.org/PathwayBrowser/#/R-CFA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Canis familiaris 16247 R-CFA-174739 https://reactome.org/PathwayBrowser/#/R-CFA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Canis familiaris 16247 R-CFA-174741 https://reactome.org/PathwayBrowser/#/R-CFA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Canis familiaris 16247 R-CFA-174757 https://reactome.org/PathwayBrowser/#/R-CFA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Canis familiaris 16247 R-CFA-174786 https://reactome.org/PathwayBrowser/#/R-CFA-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Canis familiaris 16247 R-CFA-203130 https://reactome.org/PathwayBrowser/#/R-CFA-203130 OLR1 binds to oxidized LDL IEA Canis familiaris 16247 R-CFA-216756 https://reactome.org/PathwayBrowser/#/R-CFA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Canis familiaris 16247 R-CFA-216757 https://reactome.org/PathwayBrowser/#/R-CFA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Canis familiaris 16247 R-CFA-2187332 https://reactome.org/PathwayBrowser/#/R-CFA-2187332 Cytosolic CMs translocate to extracellular region IEA Canis familiaris 16247 R-CFA-2197646 https://reactome.org/PathwayBrowser/#/R-CFA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Canis familiaris 16247 R-CFA-2197770 https://reactome.org/PathwayBrowser/#/R-CFA-2197770 STAB1 (FEEL-1) binds ligands IEA Canis familiaris 16247 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 16247 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 16247 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 16247 R-CFA-2247513 https://reactome.org/PathwayBrowser/#/R-CFA-2247513 STAB1:ligand is endocytosed IEA Canis familiaris 16247 R-CFA-2395764 https://reactome.org/PathwayBrowser/#/R-CFA-2395764 atREs binds to nascent CM IEA Canis familiaris 16247 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 16247 R-CFA-2395784 https://reactome.org/PathwayBrowser/#/R-CFA-2395784 Nascent CMs transform into mature CMs IEA Canis familiaris 16247 R-CFA-2404131 https://reactome.org/PathwayBrowser/#/R-CFA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Canis familiaris 16247 R-CFA-2423785 https://reactome.org/PathwayBrowser/#/R-CFA-2423785 CR:atREs binds apoE and HSPG IEA Canis familiaris 16247 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 16247 R-CFA-2512800 https://reactome.org/PathwayBrowser/#/R-CFA-2512800 SCARB1:ligand is endocytosed IEA Canis familiaris 16247 R-CFA-266089 https://reactome.org/PathwayBrowser/#/R-CFA-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Canis familiaris 16247 R-CFA-266299 https://reactome.org/PathwayBrowser/#/R-CFA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Canis familiaris 16247 R-CFA-266303 https://reactome.org/PathwayBrowser/#/R-CFA-266303 Spherical HDL binds C and E apolipoproteins IEA Canis familiaris 16247 R-CFA-349637 https://reactome.org/PathwayBrowser/#/R-CFA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Canis familiaris 16247 R-CFA-349638 https://reactome.org/PathwayBrowser/#/R-CFA-349638 Disassembly of SR-BI-bound spherical HDL IEA Canis familiaris 16247 R-CFA-349657 https://reactome.org/PathwayBrowser/#/R-CFA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Canis familiaris 16247 R-CFA-432121 https://reactome.org/PathwayBrowser/#/R-CFA-432121 LDL binds to LRP8 IEA Canis familiaris 16247 R-CFA-432129 https://reactome.org/PathwayBrowser/#/R-CFA-432129 FGR binds and phosphorylates LRP8 IEA Canis familiaris 16247 R-CFA-435244 https://reactome.org/PathwayBrowser/#/R-CFA-435244 PECAM1 is phosphorylated IEA Canis familiaris 16247 R-CFA-5333678 https://reactome.org/PathwayBrowser/#/R-CFA-5333678 CPNEs bind PL IEA Canis familiaris 16247 R-CFA-8854408 https://reactome.org/PathwayBrowser/#/R-CFA-8854408 APOBR dimer binds VLDLs IEA Canis familiaris 16247 R-CFA-8854462 https://reactome.org/PathwayBrowser/#/R-CFA-8854462 VLDLR binds VLDL IEA Canis familiaris 16247 R-CFA-8856630 https://reactome.org/PathwayBrowser/#/R-CFA-8856630 CIDEA:CIDEC binds lipid droplets IEA Canis familiaris 16247 R-CFA-8858252 https://reactome.org/PathwayBrowser/#/R-CFA-8858252 HDLBP binds HDL IEA Canis familiaris 16247 R-CFA-8858270 https://reactome.org/PathwayBrowser/#/R-CFA-8858270 HILPDA binds lipid droplets IEA Canis familiaris 16247 R-CFA-8863471 https://reactome.org/PathwayBrowser/#/R-CFA-8863471 LDLR is bound by DAB2 and ARH IEA Canis familiaris 16247 R-CFA-8865667 https://reactome.org/PathwayBrowser/#/R-CFA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Canis familiaris 16247 R-CFA-8866304 https://reactome.org/PathwayBrowser/#/R-CFA-8866304 pre-VLDL binds lipids to form VLDL IEA Canis familiaris 16247 R-CFA-8866308 https://reactome.org/PathwayBrowser/#/R-CFA-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Canis familiaris 16247 R-CFA-8866321 https://reactome.org/PathwayBrowser/#/R-CFA-8866321 VLDL binds APOC1 and APOC4 IEA Canis familiaris 16247 R-CFA-8866327 https://reactome.org/PathwayBrowser/#/R-CFA-8866327 VLDL translocates from SER lumen to extracellular region IEA Canis familiaris 16247 R-CFA-8866329 https://reactome.org/PathwayBrowser/#/R-CFA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Canis familiaris 16247 R-CFA-8867754 https://reactome.org/PathwayBrowser/#/R-CFA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Canis familiaris 16247 R-CFA-8867756 https://reactome.org/PathwayBrowser/#/R-CFA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Canis familiaris 16247 R-CFA-8868071 https://reactome.org/PathwayBrowser/#/R-CFA-8868071 Clathrin recruits PIK3C2A IEA Canis familiaris 16247 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 16247 R-CFA-8868230 https://reactome.org/PathwayBrowser/#/R-CFA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Canis familiaris 16247 R-CFA-8868236 https://reactome.org/PathwayBrowser/#/R-CFA-8868236 BAR domain proteins recruit dynamin IEA Canis familiaris 16247 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 16247 R-CFA-8868651 https://reactome.org/PathwayBrowser/#/R-CFA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Canis familiaris 16247 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 16247 R-CFA-8868659 https://reactome.org/PathwayBrowser/#/R-CFA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Canis familiaris 16247 R-CFA-8868660 https://reactome.org/PathwayBrowser/#/R-CFA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Canis familiaris 16247 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 16247 R-CFA-8871193 https://reactome.org/PathwayBrowser/#/R-CFA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Canis familiaris 16247 R-CFA-8871194 https://reactome.org/PathwayBrowser/#/R-CFA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Canis familiaris 16247 R-CFA-8876366 https://reactome.org/PathwayBrowser/#/R-CFA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Canis familiaris 16247 R-CFA-8948034 https://reactome.org/PathwayBrowser/#/R-CFA-8948034 FGR binds LDL:LRP8 IEA Canis familiaris 16247 R-CFA-9707586 https://reactome.org/PathwayBrowser/#/R-CFA-9707586 FeHM oxidises LDL,HDL IEA Canis familiaris 16247 R-CFA-9737780 https://reactome.org/PathwayBrowser/#/R-CFA-9737780 MTTP binds lomitapide IEA Canis familiaris 16247 R-DDI-5333678 https://reactome.org/PathwayBrowser/#/R-DDI-5333678 CPNEs bind PL IEA Dictyostelium discoideum 16247 R-DME-8856630 https://reactome.org/PathwayBrowser/#/R-DME-8856630 CIDEA:CIDEC binds lipid droplets IEA Drosophila melanogaster 16247 R-DME-8862380 https://reactome.org/PathwayBrowser/#/R-DME-8862380 HSD17B13 binds lipid droplets IEA Drosophila melanogaster 16247 R-DME-9737780 https://reactome.org/PathwayBrowser/#/R-DME-9737780 MTTP binds lomitapide IEA Drosophila melanogaster 16247 R-DRE-216756 https://reactome.org/PathwayBrowser/#/R-DRE-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Danio rerio 16247 R-DRE-216757 https://reactome.org/PathwayBrowser/#/R-DRE-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Danio rerio 16247 R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 16247 R-DRE-266089 https://reactome.org/PathwayBrowser/#/R-DRE-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Danio rerio 16247 R-DRE-266299 https://reactome.org/PathwayBrowser/#/R-DRE-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Danio rerio 16247 R-DRE-349657 https://reactome.org/PathwayBrowser/#/R-DRE-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Danio rerio 16247 R-DRE-5333678 https://reactome.org/PathwayBrowser/#/R-DRE-5333678 CPNEs bind PL IEA Danio rerio 16247 R-DRE-9737780 https://reactome.org/PathwayBrowser/#/R-DRE-9737780 MTTP binds lomitapide IEA Danio rerio 16247 R-GGA-174587 https://reactome.org/PathwayBrowser/#/R-GGA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Gallus gallus 16247 R-GGA-174786 https://reactome.org/PathwayBrowser/#/R-GGA-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Gallus gallus 16247 R-GGA-216756 https://reactome.org/PathwayBrowser/#/R-GGA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Gallus gallus 16247 R-GGA-216757 https://reactome.org/PathwayBrowser/#/R-GGA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Gallus gallus 16247 R-GGA-2187332 https://reactome.org/PathwayBrowser/#/R-GGA-2187332 Cytosolic CMs translocate to extracellular region IEA Gallus gallus 16247 R-GGA-2197646 https://reactome.org/PathwayBrowser/#/R-GGA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Gallus gallus 16247 R-GGA-2197770 https://reactome.org/PathwayBrowser/#/R-GGA-2197770 STAB1 (FEEL-1) binds ligands IEA Gallus gallus 16247 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 16247 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 16247 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 16247 R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus 16247 R-GGA-2395764 https://reactome.org/PathwayBrowser/#/R-GGA-2395764 atREs binds to nascent CM IEA Gallus gallus 16247 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 16247 R-GGA-2512800 https://reactome.org/PathwayBrowser/#/R-GGA-2512800 SCARB1:ligand is endocytosed IEA Gallus gallus 16247 R-GGA-264678 https://reactome.org/PathwayBrowser/#/R-GGA-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Gallus gallus 16247 R-GGA-264689 https://reactome.org/PathwayBrowser/#/R-GGA-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Gallus gallus 16247 R-GGA-266089 https://reactome.org/PathwayBrowser/#/R-GGA-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Gallus gallus 16247 R-GGA-266299 https://reactome.org/PathwayBrowser/#/R-GGA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Gallus gallus 16247 R-GGA-266310 https://reactome.org/PathwayBrowser/#/R-GGA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Gallus gallus 16247 R-GGA-266315 https://reactome.org/PathwayBrowser/#/R-GGA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Gallus gallus 16247 R-GGA-266328 https://reactome.org/PathwayBrowser/#/R-GGA-266328 CETP-mediated lipid exchange: spherical HDL gains triacylglycerol IEA Gallus gallus 16247 R-GGA-266350 https://reactome.org/PathwayBrowser/#/R-GGA-266350 CETP-mediated lipid exchange: LDL gains cholesterol ester IEA Gallus gallus 16247 R-GGA-349404 https://reactome.org/PathwayBrowser/#/R-GGA-349404 CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex IEA Gallus gallus 16247 R-GGA-349637 https://reactome.org/PathwayBrowser/#/R-GGA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Gallus gallus 16247 R-GGA-349638 https://reactome.org/PathwayBrowser/#/R-GGA-349638 Disassembly of SR-BI-bound spherical HDL IEA Gallus gallus 16247 R-GGA-349657 https://reactome.org/PathwayBrowser/#/R-GGA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Gallus gallus 16247 R-GGA-432121 https://reactome.org/PathwayBrowser/#/R-GGA-432121 LDL binds to LRP8 IEA Gallus gallus 16247 R-GGA-432129 https://reactome.org/PathwayBrowser/#/R-GGA-432129 FGR binds and phosphorylates LRP8 IEA Gallus gallus 16247 R-GGA-435244 https://reactome.org/PathwayBrowser/#/R-GGA-435244 PECAM1 is phosphorylated IEA Gallus gallus 16247 R-GGA-5333678 https://reactome.org/PathwayBrowser/#/R-GGA-5333678 CPNEs bind PL IEA Gallus gallus 16247 R-GGA-8856630 https://reactome.org/PathwayBrowser/#/R-GGA-8856630 CIDEA:CIDEC binds lipid droplets IEA Gallus gallus 16247 R-GGA-8858252 https://reactome.org/PathwayBrowser/#/R-GGA-8858252 HDLBP binds HDL IEA Gallus gallus 16247 R-GGA-8862380 https://reactome.org/PathwayBrowser/#/R-GGA-8862380 HSD17B13 binds lipid droplets IEA Gallus gallus 16247 R-GGA-8865667 https://reactome.org/PathwayBrowser/#/R-GGA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Gallus gallus 16247 R-GGA-8866304 https://reactome.org/PathwayBrowser/#/R-GGA-8866304 pre-VLDL binds lipids to form VLDL IEA Gallus gallus 16247 R-GGA-8866308 https://reactome.org/PathwayBrowser/#/R-GGA-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Gallus gallus 16247 R-GGA-8866327 https://reactome.org/PathwayBrowser/#/R-GGA-8866327 VLDL translocates from SER lumen to extracellular region IEA Gallus gallus 16247 R-GGA-8866329 https://reactome.org/PathwayBrowser/#/R-GGA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Gallus gallus 16247 R-GGA-8869667 https://reactome.org/PathwayBrowser/#/R-GGA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Gallus gallus 16247 R-GGA-8876366 https://reactome.org/PathwayBrowser/#/R-GGA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Gallus gallus 16247 R-GGA-8948034 https://reactome.org/PathwayBrowser/#/R-GGA-8948034 FGR binds LDL:LRP8 IEA Gallus gallus 16247 R-GGA-9707586 https://reactome.org/PathwayBrowser/#/R-GGA-9707586 FeHM oxidises LDL,HDL IEA Gallus gallus 16247 R-GGA-9737780 https://reactome.org/PathwayBrowser/#/R-GGA-9737780 MTTP binds lomitapide IEA Gallus gallus 16247 R-HSA-171059 https://reactome.org/PathwayBrowser/#/R-HSA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] TAS Homo sapiens 16247 R-HSA-171106 https://reactome.org/PathwayBrowser/#/R-HSA-171106 LDLR:LDL complex => LDLR + LDL TAS Homo sapiens 16247 R-HSA-171122 https://reactome.org/PathwayBrowser/#/R-HSA-171122 LDL + LDLR => LDL:LDLR complex TAS Homo sapiens 16247 R-HSA-171141 https://reactome.org/PathwayBrowser/#/R-HSA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) TAS Homo sapiens 16247 R-HSA-174587 https://reactome.org/PathwayBrowser/#/R-HSA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] TAS Homo sapiens 16247 R-HSA-174624 https://reactome.org/PathwayBrowser/#/R-HSA-174624 chylomicron remnant:apoE:LDLR complex => chylomicron remnant:apoE + LDLR IEA Homo sapiens 16247 R-HSA-174657 https://reactome.org/PathwayBrowser/#/R-HSA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex TAS Homo sapiens 16247 R-HSA-174660 https://reactome.org/PathwayBrowser/#/R-HSA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron TAS Homo sapiens 16247 R-HSA-174690 https://reactome.org/PathwayBrowser/#/R-HSA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III TAS Homo sapiens 16247 R-HSA-174706 https://reactome.org/PathwayBrowser/#/R-HSA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) TAS Homo sapiens 16247 R-HSA-174739 https://reactome.org/PathwayBrowser/#/R-HSA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex TAS Homo sapiens 16247 R-HSA-174741 https://reactome.org/PathwayBrowser/#/R-HSA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron TAS Homo sapiens 16247 R-HSA-174757 https://reactome.org/PathwayBrowser/#/R-HSA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols TAS Homo sapiens 16247 R-HSA-174786 https://reactome.org/PathwayBrowser/#/R-HSA-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex TAS Homo sapiens 16247 R-HSA-174808 https://reactome.org/PathwayBrowser/#/R-HSA-174808 chylomicron remnant:apoE:LDLR complex [coated vesicle membrane] => chylomicron remnant:apoE:LDLR complex [endosome membrane] IEA Homo sapiens 16247 R-HSA-176879 https://reactome.org/PathwayBrowser/#/R-HSA-176879 apolipoprotein(a) + LDL => Lp(a) TAS Homo sapiens 16247 R-HSA-203130 https://reactome.org/PathwayBrowser/#/R-HSA-203130 OLR1 binds to oxidized LDL TAS Homo sapiens 16247 R-HSA-216756 https://reactome.org/PathwayBrowser/#/R-HSA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle TAS Homo sapiens 16247 R-HSA-216757 https://reactome.org/PathwayBrowser/#/R-HSA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane TAS Homo sapiens 16247 R-HSA-2168889 https://reactome.org/PathwayBrowser/#/R-HSA-2168889 Haptoglobin-related Protein binds Hemoglobin TAS Homo sapiens 16247 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 16247 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 16247 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 16247 R-HSA-2187332 https://reactome.org/PathwayBrowser/#/R-HSA-2187332 Cytosolic CMs translocate to extracellular region TAS Homo sapiens 16247 R-HSA-2197645 https://reactome.org/PathwayBrowser/#/R-HSA-2197645 SCARF1 (SREC-I) binds ligands IEA Homo sapiens 16247 R-HSA-2197646 https://reactome.org/PathwayBrowser/#/R-HSA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands TAS Homo sapiens 16247 R-HSA-2197770 https://reactome.org/PathwayBrowser/#/R-HSA-2197770 STAB1 (FEEL-1) binds ligands TAS Homo sapiens 16247 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 16247 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 16247 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 16247 R-HSA-2247513 https://reactome.org/PathwayBrowser/#/R-HSA-2247513 STAB1:ligand is endocytosed TAS Homo sapiens 16247 R-HSA-2247514 https://reactome.org/PathwayBrowser/#/R-HSA-2247514 SCARF1:ligand is endocytosed TAS Homo sapiens 16247 R-HSA-2395764 https://reactome.org/PathwayBrowser/#/R-HSA-2395764 atREs binds to nascent CM TAS Homo sapiens 16247 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 16247 R-HSA-2395784 https://reactome.org/PathwayBrowser/#/R-HSA-2395784 Nascent CMs transform into mature CMs TAS Homo sapiens 16247 R-HSA-2404131 https://reactome.org/PathwayBrowser/#/R-HSA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol TAS Homo sapiens 16247 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 16247 R-HSA-2423785 https://reactome.org/PathwayBrowser/#/R-HSA-2423785 CR:atREs binds apoE and HSPG TAS Homo sapiens 16247 R-HSA-2424254 https://reactome.org/PathwayBrowser/#/R-HSA-2424254 LDLR transports extracellular CR:atREs to cytosol IEA Homo sapiens 16247 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 16247 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 16247 R-HSA-2512800 https://reactome.org/PathwayBrowser/#/R-HSA-2512800 SCARB1:ligand is endocytosed TAS Homo sapiens 16247 R-HSA-264678 https://reactome.org/PathwayBrowser/#/R-HSA-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex TAS Homo sapiens 16247 R-HSA-264689 https://reactome.org/PathwayBrowser/#/R-HSA-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL TAS Homo sapiens 16247 R-HSA-266089 https://reactome.org/PathwayBrowser/#/R-HSA-266089 Discoidal HDL binds membrane-associated free cholesterol TAS Homo sapiens 16247 R-HSA-266299 https://reactome.org/PathwayBrowser/#/R-HSA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids TAS Homo sapiens 16247 R-HSA-266303 https://reactome.org/PathwayBrowser/#/R-HSA-266303 Spherical HDL binds C and E apolipoproteins TAS Homo sapiens 16247 R-HSA-266310 https://reactome.org/PathwayBrowser/#/R-HSA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL TAS Homo sapiens 16247 R-HSA-266315 https://reactome.org/PathwayBrowser/#/R-HSA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex TAS Homo sapiens 16247 R-HSA-266328 https://reactome.org/PathwayBrowser/#/R-HSA-266328 CETP-mediated lipid exchange: spherical HDL gains triacylglycerol TAS Homo sapiens 16247 R-HSA-266350 https://reactome.org/PathwayBrowser/#/R-HSA-266350 CETP-mediated lipid exchange: LDL gains cholesterol ester TAS Homo sapiens 16247 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 16247 R-HSA-349404 https://reactome.org/PathwayBrowser/#/R-HSA-349404 CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex TAS Homo sapiens 16247 R-HSA-349637 https://reactome.org/PathwayBrowser/#/R-HSA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface TAS Homo sapiens 16247 R-HSA-349638 https://reactome.org/PathwayBrowser/#/R-HSA-349638 Disassembly of SR-BI-bound spherical HDL TAS Homo sapiens 16247 R-HSA-349657 https://reactome.org/PathwayBrowser/#/R-HSA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle TAS Homo sapiens 16247 R-HSA-432121 https://reactome.org/PathwayBrowser/#/R-HSA-432121 LDL binds to LRP8 TAS Homo sapiens 16247 R-HSA-432129 https://reactome.org/PathwayBrowser/#/R-HSA-432129 FGR binds and phosphorylates LRP8 TAS Homo sapiens 16247 R-HSA-435244 https://reactome.org/PathwayBrowser/#/R-HSA-435244 PECAM1 is phosphorylated TAS Homo sapiens 16247 R-HSA-5333678 https://reactome.org/PathwayBrowser/#/R-HSA-5333678 CPNEs bind PL TAS Homo sapiens 16247 R-HSA-8854408 https://reactome.org/PathwayBrowser/#/R-HSA-8854408 APOBR dimer binds VLDLs TAS Homo sapiens 16247 R-HSA-8854462 https://reactome.org/PathwayBrowser/#/R-HSA-8854462 VLDLR binds VLDL TAS Homo sapiens 16247 R-HSA-8856630 https://reactome.org/PathwayBrowser/#/R-HSA-8856630 CIDEA:CIDEC binds lipid droplets TAS Homo sapiens 16247 R-HSA-8858252 https://reactome.org/PathwayBrowser/#/R-HSA-8858252 HDLBP binds HDL TAS Homo sapiens 16247 R-HSA-8858270 https://reactome.org/PathwayBrowser/#/R-HSA-8858270 HILPDA binds lipid droplets TAS Homo sapiens 16247 R-HSA-8862380 https://reactome.org/PathwayBrowser/#/R-HSA-8862380 HSD17B13 binds lipid droplets TAS Homo sapiens 16247 R-HSA-8863471 https://reactome.org/PathwayBrowser/#/R-HSA-8863471 LDLR is bound by DAB2 and ARH TAS Homo sapiens 16247 R-HSA-8865667 https://reactome.org/PathwayBrowser/#/R-HSA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids TAS Homo sapiens 16247 R-HSA-8866304 https://reactome.org/PathwayBrowser/#/R-HSA-8866304 pre-VLDL binds lipids to form VLDL TAS Homo sapiens 16247 R-HSA-8866308 https://reactome.org/PathwayBrowser/#/R-HSA-8866308 pre-VLDL translocates from RER membrane to SER lumen TAS Homo sapiens 16247 R-HSA-8866321 https://reactome.org/PathwayBrowser/#/R-HSA-8866321 VLDL binds APOC1 and APOC4 TAS Homo sapiens 16247 R-HSA-8866327 https://reactome.org/PathwayBrowser/#/R-HSA-8866327 VLDL translocates from SER lumen to extracellular region TAS Homo sapiens 16247 R-HSA-8866329 https://reactome.org/PathwayBrowser/#/R-HSA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL TAS Homo sapiens 16247 R-HSA-8867754 https://reactome.org/PathwayBrowser/#/R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit TAS Homo sapiens 16247 R-HSA-8867756 https://reactome.org/PathwayBrowser/#/R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit TAS Homo sapiens 16247 R-HSA-8868071 https://reactome.org/PathwayBrowser/#/R-HSA-8868071 Clathrin recruits PIK3C2A TAS Homo sapiens 16247 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 16247 R-HSA-8868230 https://reactome.org/PathwayBrowser/#/R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery TAS Homo sapiens 16247 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 16247 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 16247 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 16247 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 16247 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 16247 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 16247 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 16247 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 16247 R-HSA-8869667 https://reactome.org/PathwayBrowser/#/R-HSA-8869667 oxLDL:CD36 binds TLR4:TLR6 TAS Homo sapiens 16247 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 16247 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 16247 R-HSA-8876366 https://reactome.org/PathwayBrowser/#/R-HSA-8876366 LDL translocates from endosome lumen to lysosome lumen TAS Homo sapiens 16247 R-HSA-8933258 https://reactome.org/PathwayBrowser/#/R-HSA-8933258 LSR trimer binds LDL IEA Homo sapiens 16247 R-HSA-8933292 https://reactome.org/PathwayBrowser/#/R-HSA-8933292 LSR trimer binds VLDL IEA Homo sapiens 16247 R-HSA-8948034 https://reactome.org/PathwayBrowser/#/R-HSA-8948034 FGR binds LDL:LRP8 TAS Homo sapiens 16247 R-HSA-9631065 https://reactome.org/PathwayBrowser/#/R-HSA-9631065 Substrate translocates into late endosomal lumen IEA Homo sapiens 16247 R-HSA-9631068 https://reactome.org/PathwayBrowser/#/R-HSA-9631068 HSPA8:substrate binds late endosomal phospholipids IEA Homo sapiens 16247 R-HSA-9707586 https://reactome.org/PathwayBrowser/#/R-HSA-9707586 FeHM oxidises LDL,HDL TAS Homo sapiens 16247 R-HSA-9737780 https://reactome.org/PathwayBrowser/#/R-HSA-9737780 MTTP binds lomitapide TAS Homo sapiens 16247 R-MMU-171059 https://reactome.org/PathwayBrowser/#/R-MMU-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Mus musculus 16247 R-MMU-171106 https://reactome.org/PathwayBrowser/#/R-MMU-171106 LDLR:LDL complex => LDLR + LDL IEA Mus musculus 16247 R-MMU-171122 https://reactome.org/PathwayBrowser/#/R-MMU-171122 LDL + LDLR => LDL:LDLR complex IEA Mus musculus 16247 R-MMU-171141 https://reactome.org/PathwayBrowser/#/R-MMU-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Mus musculus 16247 R-MMU-174587 https://reactome.org/PathwayBrowser/#/R-MMU-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Mus musculus 16247 R-MMU-174657 https://reactome.org/PathwayBrowser/#/R-MMU-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Mus musculus 16247 R-MMU-174660 https://reactome.org/PathwayBrowser/#/R-MMU-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Mus musculus 16247 R-MMU-174690 https://reactome.org/PathwayBrowser/#/R-MMU-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Mus musculus 16247 R-MMU-174706 https://reactome.org/PathwayBrowser/#/R-MMU-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Mus musculus 16247 R-MMU-174739 https://reactome.org/PathwayBrowser/#/R-MMU-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Mus musculus 16247 R-MMU-174741 https://reactome.org/PathwayBrowser/#/R-MMU-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Mus musculus 16247 R-MMU-174757 https://reactome.org/PathwayBrowser/#/R-MMU-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Mus musculus 16247 R-MMU-174786 https://reactome.org/PathwayBrowser/#/R-MMU-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Mus musculus 16247 R-MMU-203130 https://reactome.org/PathwayBrowser/#/R-MMU-203130 OLR1 binds to oxidized LDL IEA Mus musculus 16247 R-MMU-216756 https://reactome.org/PathwayBrowser/#/R-MMU-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Mus musculus 16247 R-MMU-216757 https://reactome.org/PathwayBrowser/#/R-MMU-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Mus musculus 16247 R-MMU-2168889 https://reactome.org/PathwayBrowser/#/R-MMU-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Mus musculus 16247 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 16247 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 16247 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 16247 R-MMU-2187332 https://reactome.org/PathwayBrowser/#/R-MMU-2187332 Cytosolic CMs translocate to extracellular region IEA Mus musculus 16247 R-MMU-2197646 https://reactome.org/PathwayBrowser/#/R-MMU-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Mus musculus 16247 R-MMU-2197770 https://reactome.org/PathwayBrowser/#/R-MMU-2197770 STAB1 (FEEL-1) binds ligands IEA Mus musculus 16247 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 16247 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 16247 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 16247 R-MMU-2247513 https://reactome.org/PathwayBrowser/#/R-MMU-2247513 STAB1:ligand is endocytosed IEA Mus musculus 16247 R-MMU-2395764 https://reactome.org/PathwayBrowser/#/R-MMU-2395764 atREs binds to nascent CM IEA Mus musculus 16247 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 16247 R-MMU-2395784 https://reactome.org/PathwayBrowser/#/R-MMU-2395784 Nascent CMs transform into mature CMs IEA Mus musculus 16247 R-MMU-2404131 https://reactome.org/PathwayBrowser/#/R-MMU-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Mus musculus 16247 R-MMU-2423785 https://reactome.org/PathwayBrowser/#/R-MMU-2423785 CR:atREs binds apoE and HSPG IEA Mus musculus 16247 R-MMU-2425403 https://reactome.org/PathwayBrowser/#/R-MMU-2425403 Extracellular CR:atREs are transported to cytosol by Ldlr TAS Mus musculus 16247 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 16247 R-MMU-2512800 https://reactome.org/PathwayBrowser/#/R-MMU-2512800 SCARB1:ligand is endocytosed IEA Mus musculus 16247 R-MMU-264678 https://reactome.org/PathwayBrowser/#/R-MMU-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Mus musculus 16247 R-MMU-264689 https://reactome.org/PathwayBrowser/#/R-MMU-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Mus musculus 16247 R-MMU-266089 https://reactome.org/PathwayBrowser/#/R-MMU-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Mus musculus 16247 R-MMU-266299 https://reactome.org/PathwayBrowser/#/R-MMU-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Mus musculus 16247 R-MMU-266303 https://reactome.org/PathwayBrowser/#/R-MMU-266303 Spherical HDL binds C and E apolipoproteins IEA Mus musculus 16247 R-MMU-266310 https://reactome.org/PathwayBrowser/#/R-MMU-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Mus musculus 16247 R-MMU-266315 https://reactome.org/PathwayBrowser/#/R-MMU-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Mus musculus 16247 R-MMU-349637 https://reactome.org/PathwayBrowser/#/R-MMU-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Mus musculus 16247 R-MMU-349638 https://reactome.org/PathwayBrowser/#/R-MMU-349638 Disassembly of SR-BI-bound spherical HDL IEA Mus musculus 16247 R-MMU-349657 https://reactome.org/PathwayBrowser/#/R-MMU-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Mus musculus 16247 R-MMU-432121 https://reactome.org/PathwayBrowser/#/R-MMU-432121 LDL binds to LRP8 IEA Mus musculus 16247 R-MMU-432129 https://reactome.org/PathwayBrowser/#/R-MMU-432129 FGR binds and phosphorylates LRP8 IEA Mus musculus 16247 R-MMU-435244 https://reactome.org/PathwayBrowser/#/R-MMU-435244 PECAM1 is phosphorylated IEA Mus musculus 16247 R-MMU-5333678 https://reactome.org/PathwayBrowser/#/R-MMU-5333678 CPNEs bind PL IEA Mus musculus 16247 R-MMU-8854408 https://reactome.org/PathwayBrowser/#/R-MMU-8854408 APOBR dimer binds VLDLs IEA Mus musculus 16247 R-MMU-8854462 https://reactome.org/PathwayBrowser/#/R-MMU-8854462 VLDLR binds VLDL IEA Mus musculus 16247 R-MMU-8856630 https://reactome.org/PathwayBrowser/#/R-MMU-8856630 CIDEA:CIDEC binds lipid droplets IEA Mus musculus 16247 R-MMU-8858252 https://reactome.org/PathwayBrowser/#/R-MMU-8858252 HDLBP binds HDL IEA Mus musculus 16247 R-MMU-8858270 https://reactome.org/PathwayBrowser/#/R-MMU-8858270 HILPDA binds lipid droplets IEA Mus musculus 16247 R-MMU-8862380 https://reactome.org/PathwayBrowser/#/R-MMU-8862380 HSD17B13 binds lipid droplets IEA Mus musculus 16247 R-MMU-8863471 https://reactome.org/PathwayBrowser/#/R-MMU-8863471 LDLR is bound by DAB2 and ARH IEA Mus musculus 16247 R-MMU-8865667 https://reactome.org/PathwayBrowser/#/R-MMU-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Mus musculus 16247 R-MMU-8866304 https://reactome.org/PathwayBrowser/#/R-MMU-8866304 pre-VLDL binds lipids to form VLDL IEA Mus musculus 16247 R-MMU-8866308 https://reactome.org/PathwayBrowser/#/R-MMU-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Mus musculus 16247 R-MMU-8866321 https://reactome.org/PathwayBrowser/#/R-MMU-8866321 VLDL binds APOC1 and APOC4 IEA Mus musculus 16247 R-MMU-8866327 https://reactome.org/PathwayBrowser/#/R-MMU-8866327 VLDL translocates from SER lumen to extracellular region IEA Mus musculus 16247 R-MMU-8866329 https://reactome.org/PathwayBrowser/#/R-MMU-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Mus musculus 16247 R-MMU-8867754 https://reactome.org/PathwayBrowser/#/R-MMU-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Mus musculus 16247 R-MMU-8867756 https://reactome.org/PathwayBrowser/#/R-MMU-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Mus musculus 16247 R-MMU-8868071 https://reactome.org/PathwayBrowser/#/R-MMU-8868071 Clathrin recruits PIK3C2A IEA Mus musculus 16247 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 16247 R-MMU-8868236 https://reactome.org/PathwayBrowser/#/R-MMU-8868236 BAR domain proteins recruit dynamin IEA Mus musculus 16247 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 16247 R-MMU-8868651 https://reactome.org/PathwayBrowser/#/R-MMU-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Mus musculus 16247 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 16247 R-MMU-8868659 https://reactome.org/PathwayBrowser/#/R-MMU-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Mus musculus 16247 R-MMU-8868660 https://reactome.org/PathwayBrowser/#/R-MMU-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Mus musculus 16247 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 16247 R-MMU-8869667 https://reactome.org/PathwayBrowser/#/R-MMU-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Mus musculus 16247 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 16247 R-MMU-8871194 https://reactome.org/PathwayBrowser/#/R-MMU-8871194 RAB5 and GAPVD1 bind AP-2 IEA Mus musculus 16247 R-MMU-8876366 https://reactome.org/PathwayBrowser/#/R-MMU-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Mus musculus 16247 R-MMU-8933256 https://reactome.org/PathwayBrowser/#/R-MMU-8933256 Lsr trimer binds LDL TAS Mus musculus 16247 R-MMU-8933295 https://reactome.org/PathwayBrowser/#/R-MMU-8933295 Lsr trimer binds VLDL TAS Mus musculus 16247 R-MMU-8948034 https://reactome.org/PathwayBrowser/#/R-MMU-8948034 FGR binds LDL:LRP8 IEA Mus musculus 16247 R-MMU-9631076 https://reactome.org/PathwayBrowser/#/R-MMU-9631076 Hspa8:substrate binds late endosomal phospholipids TAS Mus musculus 16247 R-MMU-9631080 https://reactome.org/PathwayBrowser/#/R-MMU-9631080 Substrate translocates into late endosomal lumen TAS Mus musculus 16247 R-MMU-9707586 https://reactome.org/PathwayBrowser/#/R-MMU-9707586 FeHM oxidises LDL,HDL IEA Mus musculus 16247 R-MMU-9737780 https://reactome.org/PathwayBrowser/#/R-MMU-9737780 MTTP binds lomitapide IEA Mus musculus 16247 R-RNO-171059 https://reactome.org/PathwayBrowser/#/R-RNO-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Rattus norvegicus 16247 R-RNO-171106 https://reactome.org/PathwayBrowser/#/R-RNO-171106 LDLR:LDL complex => LDLR + LDL IEA Rattus norvegicus 16247 R-RNO-171122 https://reactome.org/PathwayBrowser/#/R-RNO-171122 LDL + LDLR => LDL:LDLR complex IEA Rattus norvegicus 16247 R-RNO-171141 https://reactome.org/PathwayBrowser/#/R-RNO-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Rattus norvegicus 16247 R-RNO-174587 https://reactome.org/PathwayBrowser/#/R-RNO-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Rattus norvegicus 16247 R-RNO-174657 https://reactome.org/PathwayBrowser/#/R-RNO-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Rattus norvegicus 16247 R-RNO-174660 https://reactome.org/PathwayBrowser/#/R-RNO-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Rattus norvegicus 16247 R-RNO-174690 https://reactome.org/PathwayBrowser/#/R-RNO-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Rattus norvegicus 16247 R-RNO-174706 https://reactome.org/PathwayBrowser/#/R-RNO-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Rattus norvegicus 16247 R-RNO-174739 https://reactome.org/PathwayBrowser/#/R-RNO-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Rattus norvegicus 16247 R-RNO-174741 https://reactome.org/PathwayBrowser/#/R-RNO-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Rattus norvegicus 16247 R-RNO-174757 https://reactome.org/PathwayBrowser/#/R-RNO-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Rattus norvegicus 16247 R-RNO-174786 https://reactome.org/PathwayBrowser/#/R-RNO-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Rattus norvegicus 16247 R-RNO-203130 https://reactome.org/PathwayBrowser/#/R-RNO-203130 OLR1 binds to oxidized LDL IEA Rattus norvegicus 16247 R-RNO-216756 https://reactome.org/PathwayBrowser/#/R-RNO-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Rattus norvegicus 16247 R-RNO-216757 https://reactome.org/PathwayBrowser/#/R-RNO-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 16247 R-RNO-2168889 https://reactome.org/PathwayBrowser/#/R-RNO-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Rattus norvegicus 16247 R-RNO-2187332 https://reactome.org/PathwayBrowser/#/R-RNO-2187332 Cytosolic CMs translocate to extracellular region IEA Rattus norvegicus 16247 R-RNO-2197646 https://reactome.org/PathwayBrowser/#/R-RNO-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Rattus norvegicus 16247 R-RNO-2197770 https://reactome.org/PathwayBrowser/#/R-RNO-2197770 STAB1 (FEEL-1) binds ligands IEA Rattus norvegicus 16247 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 16247 R-RNO-2247513 https://reactome.org/PathwayBrowser/#/R-RNO-2247513 STAB1:ligand is endocytosed IEA Rattus norvegicus 16247 R-RNO-2395764 https://reactome.org/PathwayBrowser/#/R-RNO-2395764 atREs binds to nascent CM IEA Rattus norvegicus 16247 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 16247 R-RNO-2395784 https://reactome.org/PathwayBrowser/#/R-RNO-2395784 Nascent CMs transform into mature CMs IEA Rattus norvegicus 16247 R-RNO-2404131 https://reactome.org/PathwayBrowser/#/R-RNO-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Rattus norvegicus 16247 R-RNO-2423785 https://reactome.org/PathwayBrowser/#/R-RNO-2423785 CR:atREs binds apoE and HSPG IEA Rattus norvegicus 16247 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 16247 R-RNO-2512800 https://reactome.org/PathwayBrowser/#/R-RNO-2512800 SCARB1:ligand is endocytosed IEA Rattus norvegicus 16247 R-RNO-264678 https://reactome.org/PathwayBrowser/#/R-RNO-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Rattus norvegicus 16247 R-RNO-264689 https://reactome.org/PathwayBrowser/#/R-RNO-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Rattus norvegicus 16247 R-RNO-266089 https://reactome.org/PathwayBrowser/#/R-RNO-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Rattus norvegicus 16247 R-RNO-266299 https://reactome.org/PathwayBrowser/#/R-RNO-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Rattus norvegicus 16247 R-RNO-266303 https://reactome.org/PathwayBrowser/#/R-RNO-266303 Spherical HDL binds C and E apolipoproteins IEA Rattus norvegicus 16247 R-RNO-266310 https://reactome.org/PathwayBrowser/#/R-RNO-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Rattus norvegicus 16247 R-RNO-266315 https://reactome.org/PathwayBrowser/#/R-RNO-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Rattus norvegicus 16247 R-RNO-349637 https://reactome.org/PathwayBrowser/#/R-RNO-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Rattus norvegicus 16247 R-RNO-349638 https://reactome.org/PathwayBrowser/#/R-RNO-349638 Disassembly of SR-BI-bound spherical HDL IEA Rattus norvegicus 16247 R-RNO-349657 https://reactome.org/PathwayBrowser/#/R-RNO-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Rattus norvegicus 16247 R-RNO-432121 https://reactome.org/PathwayBrowser/#/R-RNO-432121 LDL binds to LRP8 IEA Rattus norvegicus 16247 R-RNO-432129 https://reactome.org/PathwayBrowser/#/R-RNO-432129 FGR binds and phosphorylates LRP8 IEA Rattus norvegicus 16247 R-RNO-435244 https://reactome.org/PathwayBrowser/#/R-RNO-435244 PECAM1 is phosphorylated IEA Rattus norvegicus 16247 R-RNO-5333678 https://reactome.org/PathwayBrowser/#/R-RNO-5333678 CPNEs bind PL IEA Rattus norvegicus 16247 R-RNO-8854408 https://reactome.org/PathwayBrowser/#/R-RNO-8854408 APOBR dimer binds VLDLs IEA Rattus norvegicus 16247 R-RNO-8854462 https://reactome.org/PathwayBrowser/#/R-RNO-8854462 VLDLR binds VLDL IEA Rattus norvegicus 16247 R-RNO-8856630 https://reactome.org/PathwayBrowser/#/R-RNO-8856630 CIDEA:CIDEC binds lipid droplets IEA Rattus norvegicus 16247 R-RNO-8858252 https://reactome.org/PathwayBrowser/#/R-RNO-8858252 HDLBP binds HDL IEA Rattus norvegicus 16247 R-RNO-8862380 https://reactome.org/PathwayBrowser/#/R-RNO-8862380 HSD17B13 binds lipid droplets IEA Rattus norvegicus 16247 R-RNO-8863471 https://reactome.org/PathwayBrowser/#/R-RNO-8863471 LDLR is bound by DAB2 and ARH IEA Rattus norvegicus 16247 R-RNO-8865667 https://reactome.org/PathwayBrowser/#/R-RNO-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Rattus norvegicus 16247 R-RNO-8866304 https://reactome.org/PathwayBrowser/#/R-RNO-8866304 pre-VLDL binds lipids to form VLDL IEA Rattus norvegicus 16247 R-RNO-8866308 https://reactome.org/PathwayBrowser/#/R-RNO-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Rattus norvegicus 16247 R-RNO-8866321 https://reactome.org/PathwayBrowser/#/R-RNO-8866321 VLDL binds APOC1 and APOC4 IEA Rattus norvegicus 16247 R-RNO-8866327 https://reactome.org/PathwayBrowser/#/R-RNO-8866327 VLDL translocates from SER lumen to extracellular region IEA Rattus norvegicus 16247 R-RNO-8866329 https://reactome.org/PathwayBrowser/#/R-RNO-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Rattus norvegicus 16247 R-RNO-8867754 https://reactome.org/PathwayBrowser/#/R-RNO-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Rattus norvegicus 16247 R-RNO-8867756 https://reactome.org/PathwayBrowser/#/R-RNO-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Rattus norvegicus 16247 R-RNO-8868071 https://reactome.org/PathwayBrowser/#/R-RNO-8868071 Clathrin recruits PIK3C2A IEA Rattus norvegicus 16247 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 16247 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus 16247 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 16247 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus 16247 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 16247 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus 16247 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus 16247 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 16247 R-RNO-8869667 https://reactome.org/PathwayBrowser/#/R-RNO-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Rattus norvegicus 16247 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 16247 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus 16247 R-RNO-8876366 https://reactome.org/PathwayBrowser/#/R-RNO-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Rattus norvegicus 16247 R-RNO-8948034 https://reactome.org/PathwayBrowser/#/R-RNO-8948034 FGR binds LDL:LRP8 IEA Rattus norvegicus 16247 R-RNO-9707586 https://reactome.org/PathwayBrowser/#/R-RNO-9707586 FeHM oxidises LDL,HDL IEA Rattus norvegicus 16247 R-RNO-9737780 https://reactome.org/PathwayBrowser/#/R-RNO-9737780 MTTP binds lomitapide IEA Rattus norvegicus 16247 R-SCE-8862380 https://reactome.org/PathwayBrowser/#/R-SCE-8862380 HSD17B13 binds lipid droplets IEA Saccharomyces cerevisiae 16247 R-SSC-171059 https://reactome.org/PathwayBrowser/#/R-SSC-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Sus scrofa 16247 R-SSC-171106 https://reactome.org/PathwayBrowser/#/R-SSC-171106 LDLR:LDL complex => LDLR + LDL IEA Sus scrofa 16247 R-SSC-171122 https://reactome.org/PathwayBrowser/#/R-SSC-171122 LDL + LDLR => LDL:LDLR complex IEA Sus scrofa 16247 R-SSC-171141 https://reactome.org/PathwayBrowser/#/R-SSC-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Sus scrofa 16247 R-SSC-174587 https://reactome.org/PathwayBrowser/#/R-SSC-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Sus scrofa 16247 R-SSC-174657 https://reactome.org/PathwayBrowser/#/R-SSC-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Sus scrofa 16247 R-SSC-174660 https://reactome.org/PathwayBrowser/#/R-SSC-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Sus scrofa 16247 R-SSC-174690 https://reactome.org/PathwayBrowser/#/R-SSC-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Sus scrofa 16247 R-SSC-174706 https://reactome.org/PathwayBrowser/#/R-SSC-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Sus scrofa 16247 R-SSC-174739 https://reactome.org/PathwayBrowser/#/R-SSC-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Sus scrofa 16247 R-SSC-174741 https://reactome.org/PathwayBrowser/#/R-SSC-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Sus scrofa 16247 R-SSC-174757 https://reactome.org/PathwayBrowser/#/R-SSC-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Sus scrofa 16247 R-SSC-174786 https://reactome.org/PathwayBrowser/#/R-SSC-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Sus scrofa 16247 R-SSC-203130 https://reactome.org/PathwayBrowser/#/R-SSC-203130 OLR1 binds to oxidized LDL IEA Sus scrofa 16247 R-SSC-216756 https://reactome.org/PathwayBrowser/#/R-SSC-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Sus scrofa 16247 R-SSC-216757 https://reactome.org/PathwayBrowser/#/R-SSC-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Sus scrofa 16247 R-SSC-2168889 https://reactome.org/PathwayBrowser/#/R-SSC-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Sus scrofa 16247 R-SSC-2187332 https://reactome.org/PathwayBrowser/#/R-SSC-2187332 Cytosolic CMs translocate to extracellular region IEA Sus scrofa 16247 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa 16247 R-SSC-2197770 https://reactome.org/PathwayBrowser/#/R-SSC-2197770 STAB1 (FEEL-1) binds ligands IEA Sus scrofa 16247 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 16247 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 16247 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 16247 R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa 16247 R-SSC-2395764 https://reactome.org/PathwayBrowser/#/R-SSC-2395764 atREs binds to nascent CM IEA Sus scrofa 16247 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 16247 R-SSC-2395784 https://reactome.org/PathwayBrowser/#/R-SSC-2395784 Nascent CMs transform into mature CMs IEA Sus scrofa 16247 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa 16247 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa 16247 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 16247 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa 16247 R-SSC-264678 https://reactome.org/PathwayBrowser/#/R-SSC-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Sus scrofa 16247 R-SSC-264689 https://reactome.org/PathwayBrowser/#/R-SSC-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Sus scrofa 16247 R-SSC-266089 https://reactome.org/PathwayBrowser/#/R-SSC-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Sus scrofa 16247 R-SSC-266299 https://reactome.org/PathwayBrowser/#/R-SSC-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Sus scrofa 16247 R-SSC-266303 https://reactome.org/PathwayBrowser/#/R-SSC-266303 Spherical HDL binds C and E apolipoproteins IEA Sus scrofa 16247 R-SSC-266310 https://reactome.org/PathwayBrowser/#/R-SSC-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Sus scrofa 16247 R-SSC-266315 https://reactome.org/PathwayBrowser/#/R-SSC-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Sus scrofa 16247 R-SSC-349637 https://reactome.org/PathwayBrowser/#/R-SSC-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Sus scrofa 16247 R-SSC-349638 https://reactome.org/PathwayBrowser/#/R-SSC-349638 Disassembly of SR-BI-bound spherical HDL IEA Sus scrofa 16247 R-SSC-349657 https://reactome.org/PathwayBrowser/#/R-SSC-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Sus scrofa 16247 R-SSC-432121 https://reactome.org/PathwayBrowser/#/R-SSC-432121 LDL binds to LRP8 IEA Sus scrofa 16247 R-SSC-432129 https://reactome.org/PathwayBrowser/#/R-SSC-432129 FGR binds and phosphorylates LRP8 IEA Sus scrofa 16247 R-SSC-435244 https://reactome.org/PathwayBrowser/#/R-SSC-435244 PECAM1 is phosphorylated IEA Sus scrofa 16247 R-SSC-5333678 https://reactome.org/PathwayBrowser/#/R-SSC-5333678 CPNEs bind PL IEA Sus scrofa 16247 R-SSC-8856630 https://reactome.org/PathwayBrowser/#/R-SSC-8856630 CIDEA:CIDEC binds lipid droplets IEA Sus scrofa 16247 R-SSC-8858252 https://reactome.org/PathwayBrowser/#/R-SSC-8858252 HDLBP binds HDL IEA Sus scrofa 16247 R-SSC-8858270 https://reactome.org/PathwayBrowser/#/R-SSC-8858270 HILPDA binds lipid droplets IEA Sus scrofa 16247 R-SSC-8862380 https://reactome.org/PathwayBrowser/#/R-SSC-8862380 HSD17B13 binds lipid droplets IEA Sus scrofa 16247 R-SSC-8863471 https://reactome.org/PathwayBrowser/#/R-SSC-8863471 LDLR is bound by DAB2 and ARH IEA Sus scrofa 16247 R-SSC-8865667 https://reactome.org/PathwayBrowser/#/R-SSC-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Sus scrofa 16247 R-SSC-8866304 https://reactome.org/PathwayBrowser/#/R-SSC-8866304 pre-VLDL binds lipids to form VLDL IEA Sus scrofa 16247 R-SSC-8866308 https://reactome.org/PathwayBrowser/#/R-SSC-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Sus scrofa 16247 R-SSC-8866327 https://reactome.org/PathwayBrowser/#/R-SSC-8866327 VLDL translocates from SER lumen to extracellular region IEA Sus scrofa 16247 R-SSC-8866329 https://reactome.org/PathwayBrowser/#/R-SSC-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Sus scrofa 16247 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa 16247 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa 16247 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa 16247 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 16247 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa 16247 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa 16247 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 16247 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa 16247 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 16247 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa 16247 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa 16247 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 16247 R-SSC-8869667 https://reactome.org/PathwayBrowser/#/R-SSC-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Sus scrofa 16247 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 16247 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa 16247 R-SSC-8876366 https://reactome.org/PathwayBrowser/#/R-SSC-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Sus scrofa 16247 R-SSC-8948034 https://reactome.org/PathwayBrowser/#/R-SSC-8948034 FGR binds LDL:LRP8 IEA Sus scrofa 16247 R-SSC-9707586 https://reactome.org/PathwayBrowser/#/R-SSC-9707586 FeHM oxidises LDL,HDL IEA Sus scrofa 16247 R-SSC-9737780 https://reactome.org/PathwayBrowser/#/R-SSC-9737780 MTTP binds lomitapide IEA Sus scrofa 16247 R-XTR-5333678 https://reactome.org/PathwayBrowser/#/R-XTR-5333678 CPNEs bind PL IEA Xenopus tropicalis 16247 R-XTR-8856630 https://reactome.org/PathwayBrowser/#/R-XTR-8856630 CIDEA:CIDEC binds lipid droplets IEA Xenopus tropicalis 16247 R-XTR-8862380 https://reactome.org/PathwayBrowser/#/R-XTR-8862380 HSD17B13 binds lipid droplets IEA Xenopus tropicalis 16247 R-XTR-9737780 https://reactome.org/PathwayBrowser/#/R-XTR-9737780 MTTP binds lomitapide IEA Xenopus tropicalis 16254 R-BTA-2465919 https://reactome.org/PathwayBrowser/#/R-BTA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Bos taurus 16254 R-CFA-2465919 https://reactome.org/PathwayBrowser/#/R-CFA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Canis familiaris 16254 R-DDI-2465919 https://reactome.org/PathwayBrowser/#/R-DDI-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Dictyostelium discoideum 16254 R-DME-2465919 https://reactome.org/PathwayBrowser/#/R-DME-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Drosophila melanogaster 16254 R-DRE-2465919 https://reactome.org/PathwayBrowser/#/R-DRE-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Danio rerio 16254 R-GGA-2465919 https://reactome.org/PathwayBrowser/#/R-GGA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Gallus gallus 16254 R-GGA-2465974 https://reactome.org/PathwayBrowser/#/R-GGA-2465974 An REH hydrolyses 11cRE to 11cROL TAS Gallus gallus 16254 R-HSA-2465919 https://reactome.org/PathwayBrowser/#/R-HSA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM TAS Homo sapiens 16254 R-HSA-2465941 https://reactome.org/PathwayBrowser/#/R-HSA-2465941 A REH hydrolyses 11cRE to 11cROL IEA Homo sapiens 16254 R-MMU-2465919 https://reactome.org/PathwayBrowser/#/R-MMU-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Mus musculus 16254 R-RNO-2465919 https://reactome.org/PathwayBrowser/#/R-RNO-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Rattus norvegicus 16254 R-SSC-2465919 https://reactome.org/PathwayBrowser/#/R-SSC-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Sus scrofa 16254 R-XTR-2465919 https://reactome.org/PathwayBrowser/#/R-XTR-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Xenopus tropicalis 16283 R-BTA-379432 https://reactome.org/PathwayBrowser/#/R-BTA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Bos taurus 16283 R-BTA-5340130 https://reactome.org/PathwayBrowser/#/R-BTA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Bos taurus 16283 R-CEL-5340130 https://reactome.org/PathwayBrowser/#/R-CEL-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Caenorhabditis elegans 16283 R-CFA-379432 https://reactome.org/PathwayBrowser/#/R-CFA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Canis familiaris 16283 R-CFA-5340130 https://reactome.org/PathwayBrowser/#/R-CFA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Canis familiaris 16283 R-DDI-5340130 https://reactome.org/PathwayBrowser/#/R-DDI-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Dictyostelium discoideum 16283 R-DME-379432 https://reactome.org/PathwayBrowser/#/R-DME-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Drosophila melanogaster 16283 R-DME-5340130 https://reactome.org/PathwayBrowser/#/R-DME-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Drosophila melanogaster 16283 R-DRE-5340130 https://reactome.org/PathwayBrowser/#/R-DRE-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Danio rerio 16283 R-GGA-379432 https://reactome.org/PathwayBrowser/#/R-GGA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Gallus gallus 16283 R-GGA-5340130 https://reactome.org/PathwayBrowser/#/R-GGA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Gallus gallus 16283 R-HSA-379432 https://reactome.org/PathwayBrowser/#/R-HSA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 16283 R-HSA-5340130 https://reactome.org/PathwayBrowser/#/R-HSA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol TAS Homo sapiens 16283 R-HSA-5655702 https://reactome.org/PathwayBrowser/#/R-HSA-5655702 Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 16283 R-HSA-5660890 https://reactome.org/PathwayBrowser/#/R-HSA-5660890 Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 16283 R-MMU-379432 https://reactome.org/PathwayBrowser/#/R-MMU-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Mus musculus 16283 R-MMU-5340130 https://reactome.org/PathwayBrowser/#/R-MMU-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Mus musculus 16283 R-RNO-379432 https://reactome.org/PathwayBrowser/#/R-RNO-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Rattus norvegicus 16283 R-RNO-5340130 https://reactome.org/PathwayBrowser/#/R-RNO-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Rattus norvegicus 16283 R-SCE-379432 https://reactome.org/PathwayBrowser/#/R-SCE-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Saccharomyces cerevisiae 16283 R-SCE-5340130 https://reactome.org/PathwayBrowser/#/R-SCE-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Saccharomyces cerevisiae 16283 R-SSC-379432 https://reactome.org/PathwayBrowser/#/R-SSC-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Sus scrofa 16283 R-SSC-5340130 https://reactome.org/PathwayBrowser/#/R-SSC-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Sus scrofa 16283 R-XTR-379432 https://reactome.org/PathwayBrowser/#/R-XTR-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Xenopus tropicalis 16285 R-BTA-389622 https://reactome.org/PathwayBrowser/#/R-BTA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 16285 R-CEL-389622 https://reactome.org/PathwayBrowser/#/R-CEL-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 16285 R-CFA-389622 https://reactome.org/PathwayBrowser/#/R-CFA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 16285 R-DME-389622 https://reactome.org/PathwayBrowser/#/R-DME-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 16285 R-GGA-389622 https://reactome.org/PathwayBrowser/#/R-GGA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 16285 R-HSA-389622 https://reactome.org/PathwayBrowser/#/R-HSA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 16285 R-HSA-9844415 https://reactome.org/PathwayBrowser/#/R-HSA-9844415 PRDM16 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 IEA Homo sapiens 16285 R-HSA-9844440 https://reactome.org/PathwayBrowser/#/R-HSA-9844440 PPARG binds EBF2-bound gene loci IEA Homo sapiens 16285 R-HSA-9844536 https://reactome.org/PathwayBrowser/#/R-HSA-9844536 PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 16285 R-HSA-9844549 https://reactome.org/PathwayBrowser/#/R-HSA-9844549 UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 16285 R-HSA-9844600 https://reactome.org/PathwayBrowser/#/R-HSA-9844600 CIDEA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 16285 R-HSA-9844822 https://reactome.org/PathwayBrowser/#/R-HSA-9844822 PPARGC1A gene expression is stimulated by EBF2 IEA Homo sapiens 16285 R-MMU-389622 https://reactome.org/PathwayBrowser/#/R-MMU-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 16285 R-MMU-9844541 https://reactome.org/PathwayBrowser/#/R-MMU-9844541 Ppara gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 16285 R-MMU-9844554 https://reactome.org/PathwayBrowser/#/R-MMU-9844554 Ucp1 gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 16285 R-MMU-9844626 https://reactome.org/PathwayBrowser/#/R-MMU-9844626 Cidea gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 16285 R-MMU-9844655 https://reactome.org/PathwayBrowser/#/R-MMU-9844655 Dio2 gene expression is stimulated by Ebf2 and repressed by Znf423 and NuRD TAS Mus musculus 16285 R-MMU-9844700 https://reactome.org/PathwayBrowser/#/R-MMU-9844700 Pparg binds Ebf2-bound gene loci TAS Mus musculus 16285 R-MMU-9844775 https://reactome.org/PathwayBrowser/#/R-MMU-9844775 Prdm16 gene expression is stimulated by Ebf2 and Pparg and inhibited by Znf423 TAS Mus musculus 16285 R-MMU-9844841 https://reactome.org/PathwayBrowser/#/R-MMU-9844841 Ppargc1a gene expression is positively regulated by Ebf2 and Pparg TAS Mus musculus 16285 R-RNO-389622 https://reactome.org/PathwayBrowser/#/R-RNO-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 16285 R-SCE-389622 https://reactome.org/PathwayBrowser/#/R-SCE-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 16285 R-SSC-389622 https://reactome.org/PathwayBrowser/#/R-SSC-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 16285 R-XTR-389622 https://reactome.org/PathwayBrowser/#/R-XTR-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 16290 R-BTA-195664 https://reactome.org/PathwayBrowser/#/R-BTA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Bos taurus 16290 R-BTA-195690 https://reactome.org/PathwayBrowser/#/R-BTA-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Bos taurus 16290 R-CFA-195664 https://reactome.org/PathwayBrowser/#/R-CFA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Canis familiaris 16290 R-CFA-195690 https://reactome.org/PathwayBrowser/#/R-CFA-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Canis familiaris 16290 R-DDI-195690 https://reactome.org/PathwayBrowser/#/R-DDI-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Dictyostelium discoideum 16290 R-DRE-195664 https://reactome.org/PathwayBrowser/#/R-DRE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Danio rerio 16290 R-DRE-195690 https://reactome.org/PathwayBrowser/#/R-DRE-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Danio rerio 16290 R-GGA-195664 https://reactome.org/PathwayBrowser/#/R-GGA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Gallus gallus 16290 R-GGA-195690 https://reactome.org/PathwayBrowser/#/R-GGA-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Gallus gallus 16290 R-HSA-195664 https://reactome.org/PathwayBrowser/#/R-HSA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol TAS Homo sapiens 16290 R-HSA-195690 https://reactome.org/PathwayBrowser/#/R-HSA-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol TAS Homo sapiens 16290 R-MMU-195664 https://reactome.org/PathwayBrowser/#/R-MMU-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Mus musculus 16290 R-MMU-195690 https://reactome.org/PathwayBrowser/#/R-MMU-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Mus musculus 16290 R-RNO-195664 https://reactome.org/PathwayBrowser/#/R-RNO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Rattus norvegicus 16290 R-RNO-195690 https://reactome.org/PathwayBrowser/#/R-RNO-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Rattus norvegicus 16290 R-SCE-195664 https://reactome.org/PathwayBrowser/#/R-SCE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Saccharomyces cerevisiae 16290 R-SPO-195664 https://reactome.org/PathwayBrowser/#/R-SPO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Schizosaccharomyces pombe 16290 R-SSC-195664 https://reactome.org/PathwayBrowser/#/R-SSC-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Sus scrofa 16290 R-SSC-195690 https://reactome.org/PathwayBrowser/#/R-SSC-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Sus scrofa 16290 R-XTR-195664 https://reactome.org/PathwayBrowser/#/R-XTR-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Xenopus tropicalis 16296 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 16296 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 16296 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 16296 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 16296 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 16296 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 16296 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 16296 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 16296 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 16296 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 16296 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 16296 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 16296 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 16296 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 16296 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 16296 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 16296 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 16296 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 16296 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 16296 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 16296 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 16296 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 16296 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 16296 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 16296 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 16296 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 16296 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 16296 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 16296 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 16301 R-BTA-3697882 https://reactome.org/PathwayBrowser/#/R-BTA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Bos taurus 16301 R-BTA-3697894 https://reactome.org/PathwayBrowser/#/R-BTA-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Bos taurus 16301 R-BTA-8933635 https://reactome.org/PathwayBrowser/#/R-BTA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Bos taurus 16301 R-CEL-8933635 https://reactome.org/PathwayBrowser/#/R-CEL-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Caenorhabditis elegans 16301 R-CFA-3697882 https://reactome.org/PathwayBrowser/#/R-CFA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Canis familiaris 16301 R-CFA-8933635 https://reactome.org/PathwayBrowser/#/R-CFA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Canis familiaris 16301 R-DDI-3697882 https://reactome.org/PathwayBrowser/#/R-DDI-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Dictyostelium discoideum 16301 R-DDI-3697894 https://reactome.org/PathwayBrowser/#/R-DDI-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Dictyostelium discoideum 16301 R-DDI-8933635 https://reactome.org/PathwayBrowser/#/R-DDI-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Dictyostelium discoideum 16301 R-DME-3697882 https://reactome.org/PathwayBrowser/#/R-DME-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Drosophila melanogaster 16301 R-DME-3697894 https://reactome.org/PathwayBrowser/#/R-DME-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Drosophila melanogaster 16301 R-DME-8933635 https://reactome.org/PathwayBrowser/#/R-DME-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Drosophila melanogaster 16301 R-DRE-3697882 https://reactome.org/PathwayBrowser/#/R-DRE-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Danio rerio 16301 R-DRE-3697894 https://reactome.org/PathwayBrowser/#/R-DRE-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Danio rerio 16301 R-GGA-8933635 https://reactome.org/PathwayBrowser/#/R-GGA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Gallus gallus 16301 R-HSA-1222411 https://reactome.org/PathwayBrowser/#/R-HSA-1222411 Peroxynitrite oxidizes Peptide-Methionine residues TAS Homo sapiens 16301 R-HSA-1222431 https://reactome.org/PathwayBrowser/#/R-HSA-1222431 Peroxynitrite is reduced to nitrite by AhpC TAS Homo sapiens 16301 R-HSA-1222755 https://reactome.org/PathwayBrowser/#/R-HSA-1222755 Peroxynitrite is reduced to nitrite by Tpx TAS Homo sapiens 16301 R-HSA-1500804 https://reactome.org/PathwayBrowser/#/R-HSA-1500804 Peroxynitrite is reduced by AhpE TAS Homo sapiens 16301 R-HSA-3697882 https://reactome.org/PathwayBrowser/#/R-HSA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN TAS Homo sapiens 16301 R-HSA-3697894 https://reactome.org/PathwayBrowser/#/R-HSA-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 TAS Homo sapiens 16301 R-HSA-6788974 https://reactome.org/PathwayBrowser/#/R-HSA-6788974 Hypochlorous acid and nitrite react to nitryl chloride (NO2Cl) TAS Homo sapiens 16301 R-HSA-6803978 https://reactome.org/PathwayBrowser/#/R-HSA-6803978 S-nitrosylation of cysteine residues in proteins by N2O3 TAS Homo sapiens 16301 R-HSA-6803998 https://reactome.org/PathwayBrowser/#/R-HSA-6803998 Nitrite ion and HNO2 form a conjugated acid-base pair TAS Homo sapiens 16301 R-HSA-8933635 https://reactome.org/PathwayBrowser/#/R-HSA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide TAS Homo sapiens 16301 R-HSA-8948180 https://reactome.org/PathwayBrowser/#/R-HSA-8948180 Peroxynitrite oxidizes Cys residues TAS Homo sapiens 16301 R-MMU-3697882 https://reactome.org/PathwayBrowser/#/R-MMU-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Mus musculus 16301 R-MMU-3697894 https://reactome.org/PathwayBrowser/#/R-MMU-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Mus musculus 16301 R-MMU-8933635 https://reactome.org/PathwayBrowser/#/R-MMU-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Mus musculus 16301 R-PFA-3697882 https://reactome.org/PathwayBrowser/#/R-PFA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Plasmodium falciparum 16301 R-RNO-3697882 https://reactome.org/PathwayBrowser/#/R-RNO-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Rattus norvegicus 16301 R-RNO-3697894 https://reactome.org/PathwayBrowser/#/R-RNO-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Rattus norvegicus 16301 R-RNO-8933635 https://reactome.org/PathwayBrowser/#/R-RNO-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Rattus norvegicus 16301 R-SCE-3697882 https://reactome.org/PathwayBrowser/#/R-SCE-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Saccharomyces cerevisiae 16301 R-SPO-3697882 https://reactome.org/PathwayBrowser/#/R-SPO-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Schizosaccharomyces pombe 16301 R-SSC-3697882 https://reactome.org/PathwayBrowser/#/R-SSC-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Sus scrofa 16301 R-SSC-3697894 https://reactome.org/PathwayBrowser/#/R-SSC-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Sus scrofa 16301 R-SSC-8933635 https://reactome.org/PathwayBrowser/#/R-SSC-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Sus scrofa 16301 R-XTR-3697894 https://reactome.org/PathwayBrowser/#/R-XTR-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Xenopus tropicalis 16302 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 16302 R-BTA-2454081 https://reactome.org/PathwayBrowser/#/R-BTA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Bos taurus 16302 R-BTA-2454264 https://reactome.org/PathwayBrowser/#/R-BTA-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Bos taurus 16302 R-BTA-2465919 https://reactome.org/PathwayBrowser/#/R-BTA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Bos taurus 16302 R-BTA-2465934 https://reactome.org/PathwayBrowser/#/R-BTA-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Bos taurus 16302 R-BTA-5362721 https://reactome.org/PathwayBrowser/#/R-BTA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Bos taurus 16302 R-BTA-74872 https://reactome.org/PathwayBrowser/#/R-BTA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Bos taurus 16302 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 16302 R-CEL-5362721 https://reactome.org/PathwayBrowser/#/R-CEL-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Caenorhabditis elegans 16302 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 16302 R-CFA-2454081 https://reactome.org/PathwayBrowser/#/R-CFA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Canis familiaris 16302 R-CFA-2454264 https://reactome.org/PathwayBrowser/#/R-CFA-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Canis familiaris 16302 R-CFA-2465919 https://reactome.org/PathwayBrowser/#/R-CFA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Canis familiaris 16302 R-CFA-2465934 https://reactome.org/PathwayBrowser/#/R-CFA-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Canis familiaris 16302 R-CFA-5362721 https://reactome.org/PathwayBrowser/#/R-CFA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Canis familiaris 16302 R-CFA-74872 https://reactome.org/PathwayBrowser/#/R-CFA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Canis familiaris 16302 R-DDI-2454264 https://reactome.org/PathwayBrowser/#/R-DDI-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Dictyostelium discoideum 16302 R-DDI-2465919 https://reactome.org/PathwayBrowser/#/R-DDI-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Dictyostelium discoideum 16302 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 16302 R-DME-2454264 https://reactome.org/PathwayBrowser/#/R-DME-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Drosophila melanogaster 16302 R-DME-2465919 https://reactome.org/PathwayBrowser/#/R-DME-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Drosophila melanogaster 16302 R-DME-5362721 https://reactome.org/PathwayBrowser/#/R-DME-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 16302 R-DME-74872 https://reactome.org/PathwayBrowser/#/R-DME-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 16302 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 16302 R-DRE-2454081 https://reactome.org/PathwayBrowser/#/R-DRE-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Danio rerio 16302 R-DRE-2454264 https://reactome.org/PathwayBrowser/#/R-DRE-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Danio rerio 16302 R-DRE-2465919 https://reactome.org/PathwayBrowser/#/R-DRE-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Danio rerio 16302 R-DRE-5362721 https://reactome.org/PathwayBrowser/#/R-DRE-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Danio rerio 16302 R-DRE-74872 https://reactome.org/PathwayBrowser/#/R-DRE-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Danio rerio 16302 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 16302 R-GGA-2454081 https://reactome.org/PathwayBrowser/#/R-GGA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Gallus gallus 16302 R-GGA-2454264 https://reactome.org/PathwayBrowser/#/R-GGA-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Gallus gallus 16302 R-GGA-2465919 https://reactome.org/PathwayBrowser/#/R-GGA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Gallus gallus 16302 R-GGA-2465929 https://reactome.org/PathwayBrowser/#/R-GGA-2465929 Isomerase II isomerises atROL to 11cROL TAS Gallus gallus 16302 R-GGA-2465934 https://reactome.org/PathwayBrowser/#/R-GGA-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Gallus gallus 16302 R-GGA-2465974 https://reactome.org/PathwayBrowser/#/R-GGA-2465974 An REH hydrolyses 11cRE to 11cROL TAS Gallus gallus 16302 R-GGA-5362721 https://reactome.org/PathwayBrowser/#/R-GGA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Gallus gallus 16302 R-GGA-74872 https://reactome.org/PathwayBrowser/#/R-GGA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Gallus gallus 16302 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 16302 R-HSA-2454081 https://reactome.org/PathwayBrowser/#/R-HSA-2454081 RDH5 oxidises 11cROL to 11cRAL TAS Homo sapiens 16302 R-HSA-2454264 https://reactome.org/PathwayBrowser/#/R-HSA-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL TAS Homo sapiens 16302 R-HSA-2465919 https://reactome.org/PathwayBrowser/#/R-HSA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM TAS Homo sapiens 16302 R-HSA-2465921 https://reactome.org/PathwayBrowser/#/R-HSA-2465921 11cRDH oxidises 11cROL to 11cRAL TAS Homo sapiens 16302 R-HSA-2465926 https://reactome.org/PathwayBrowser/#/R-HSA-2465926 An atROL isomerase isomerises atROL to 11cROL IEA Homo sapiens 16302 R-HSA-2465934 https://reactome.org/PathwayBrowser/#/R-HSA-2465934 11cROL translocates from Muller cells to cone photoreceptor cells TAS Homo sapiens 16302 R-HSA-2465941 https://reactome.org/PathwayBrowser/#/R-HSA-2465941 A REH hydrolyses 11cRE to 11cROL IEA Homo sapiens 16302 R-HSA-2466832 https://reactome.org/PathwayBrowser/#/R-HSA-2466832 Defective RDH5 does not oxidise 11cROL to 11cRAL and causes RPA TAS Homo sapiens 16302 R-HSA-5362721 https://reactome.org/PathwayBrowser/#/R-HSA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL TAS Homo sapiens 16302 R-HSA-74872 https://reactome.org/PathwayBrowser/#/R-HSA-74872 RDH10,11 oxidise 11cROL to 11cRAL TAS Homo sapiens 16302 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 16302 R-MMU-2454081 https://reactome.org/PathwayBrowser/#/R-MMU-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Mus musculus 16302 R-MMU-2454264 https://reactome.org/PathwayBrowser/#/R-MMU-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Mus musculus 16302 R-MMU-2465919 https://reactome.org/PathwayBrowser/#/R-MMU-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Mus musculus 16302 R-MMU-2465934 https://reactome.org/PathwayBrowser/#/R-MMU-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Mus musculus 16302 R-MMU-5362721 https://reactome.org/PathwayBrowser/#/R-MMU-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Mus musculus 16302 R-MMU-74872 https://reactome.org/PathwayBrowser/#/R-MMU-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Mus musculus 16302 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 16302 R-RNO-2454264 https://reactome.org/PathwayBrowser/#/R-RNO-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Rattus norvegicus 16302 R-RNO-2465919 https://reactome.org/PathwayBrowser/#/R-RNO-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Rattus norvegicus 16302 R-RNO-2465934 https://reactome.org/PathwayBrowser/#/R-RNO-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Rattus norvegicus 16302 R-RNO-5362721 https://reactome.org/PathwayBrowser/#/R-RNO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 16302 R-RNO-74872 https://reactome.org/PathwayBrowser/#/R-RNO-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 16302 R-SPO-5362721 https://reactome.org/PathwayBrowser/#/R-SPO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Schizosaccharomyces pombe 16302 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 16302 R-SSC-2454081 https://reactome.org/PathwayBrowser/#/R-SSC-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Sus scrofa 16302 R-SSC-2454264 https://reactome.org/PathwayBrowser/#/R-SSC-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Sus scrofa 16302 R-SSC-2465919 https://reactome.org/PathwayBrowser/#/R-SSC-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Sus scrofa 16302 R-SSC-2465934 https://reactome.org/PathwayBrowser/#/R-SSC-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Sus scrofa 16302 R-SSC-5362721 https://reactome.org/PathwayBrowser/#/R-SSC-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Sus scrofa 16302 R-SSC-74872 https://reactome.org/PathwayBrowser/#/R-SSC-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Sus scrofa 16302 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 16302 R-XTR-2454081 https://reactome.org/PathwayBrowser/#/R-XTR-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Xenopus tropicalis 16302 R-XTR-2454264 https://reactome.org/PathwayBrowser/#/R-XTR-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Xenopus tropicalis 16302 R-XTR-2465919 https://reactome.org/PathwayBrowser/#/R-XTR-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Xenopus tropicalis 16302 R-XTR-2465934 https://reactome.org/PathwayBrowser/#/R-XTR-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Xenopus tropicalis 16302 R-XTR-5362721 https://reactome.org/PathwayBrowser/#/R-XTR-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 16302 R-XTR-74872 https://reactome.org/PathwayBrowser/#/R-XTR-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 16304 R-BTA-3149494 https://reactome.org/PathwayBrowser/#/R-BTA-3149494 MMACHC:cob(II)alamin binds MMADHC IEA Bos taurus 16304 R-BTA-3149518 https://reactome.org/PathwayBrowser/#/R-BTA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Bos taurus 16304 R-BTA-3149519 https://reactome.org/PathwayBrowser/#/R-BTA-3149519 MMACHC decyanates CNCbl IEA Bos taurus 16304 R-BTA-3149563 https://reactome.org/PathwayBrowser/#/R-BTA-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria IEA Bos taurus 16304 R-BTA-3159253 https://reactome.org/PathwayBrowser/#/R-BTA-3159253 MMAB adenosylates cob(I)alamin IEA Bos taurus 16304 R-BTA-3204318 https://reactome.org/PathwayBrowser/#/R-BTA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Bos taurus 16304 R-BTA-9759549 https://reactome.org/PathwayBrowser/#/R-BTA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Bos taurus 16304 R-CEL-3149494 https://reactome.org/PathwayBrowser/#/R-CEL-3149494 MMACHC:cob(II)alamin binds MMADHC IEA Caenorhabditis elegans 16304 R-CEL-3149518 https://reactome.org/PathwayBrowser/#/R-CEL-3149518 MTRR reduces cob(II)alamin to meCbl IEA Caenorhabditis elegans 16304 R-CEL-3149519 https://reactome.org/PathwayBrowser/#/R-CEL-3149519 MMACHC decyanates CNCbl IEA Caenorhabditis elegans 16304 R-CEL-3149563 https://reactome.org/PathwayBrowser/#/R-CEL-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria IEA Caenorhabditis elegans 16304 R-CEL-3159253 https://reactome.org/PathwayBrowser/#/R-CEL-3159253 MMAB adenosylates cob(I)alamin IEA Caenorhabditis elegans 16304 R-CEL-3204318 https://reactome.org/PathwayBrowser/#/R-CEL-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Caenorhabditis elegans 16304 R-CEL-9759549 https://reactome.org/PathwayBrowser/#/R-CEL-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Caenorhabditis elegans 16304 R-CFA-3149494 https://reactome.org/PathwayBrowser/#/R-CFA-3149494 MMACHC:cob(II)alamin binds MMADHC IEA Canis familiaris 16304 R-CFA-3149518 https://reactome.org/PathwayBrowser/#/R-CFA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Canis familiaris 16304 R-CFA-3149519 https://reactome.org/PathwayBrowser/#/R-CFA-3149519 MMACHC decyanates CNCbl IEA Canis familiaris 16304 R-CFA-3149563 https://reactome.org/PathwayBrowser/#/R-CFA-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria IEA Canis familiaris 16304 R-CFA-3159253 https://reactome.org/PathwayBrowser/#/R-CFA-3159253 MMAB adenosylates cob(I)alamin IEA Canis familiaris 16304 R-CFA-3204318 https://reactome.org/PathwayBrowser/#/R-CFA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Canis familiaris 16304 R-CFA-9759549 https://reactome.org/PathwayBrowser/#/R-CFA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Canis familiaris 16304 R-DDI-3149518 https://reactome.org/PathwayBrowser/#/R-DDI-3149518 MTRR reduces cob(II)alamin to meCbl IEA Dictyostelium discoideum 16304 R-DDI-3149519 https://reactome.org/PathwayBrowser/#/R-DDI-3149519 MMACHC decyanates CNCbl IEA Dictyostelium discoideum 16304 R-DDI-3159253 https://reactome.org/PathwayBrowser/#/R-DDI-3159253 MMAB adenosylates cob(I)alamin IEA Dictyostelium discoideum 16304 R-DDI-9759549 https://reactome.org/PathwayBrowser/#/R-DDI-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Dictyostelium discoideum 16304 R-DRE-3149494 https://reactome.org/PathwayBrowser/#/R-DRE-3149494 MMACHC:cob(II)alamin binds MMADHC IEA Danio rerio 16304 R-DRE-3149519 https://reactome.org/PathwayBrowser/#/R-DRE-3149519 MMACHC decyanates CNCbl IEA Danio rerio 16304 R-DRE-3149563 https://reactome.org/PathwayBrowser/#/R-DRE-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria IEA Danio rerio 16304 R-DRE-9759549 https://reactome.org/PathwayBrowser/#/R-DRE-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Danio rerio 16304 R-GGA-3149494 https://reactome.org/PathwayBrowser/#/R-GGA-3149494 MMACHC:cob(II)alamin binds MMADHC IEA Gallus gallus 16304 R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus 16304 R-GGA-3149519 https://reactome.org/PathwayBrowser/#/R-GGA-3149519 MMACHC decyanates CNCbl IEA Gallus gallus 16304 R-GGA-3149563 https://reactome.org/PathwayBrowser/#/R-GGA-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria IEA Gallus gallus 16304 R-GGA-3159253 https://reactome.org/PathwayBrowser/#/R-GGA-3159253 MMAB adenosylates cob(I)alamin IEA Gallus gallus 16304 R-GGA-3204318 https://reactome.org/PathwayBrowser/#/R-GGA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Gallus gallus 16304 R-GGA-9759549 https://reactome.org/PathwayBrowser/#/R-GGA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Gallus gallus 16304 R-HSA-3149494 https://reactome.org/PathwayBrowser/#/R-HSA-3149494 MMACHC:cob(II)alamin binds MMADHC TAS Homo sapiens 16304 R-HSA-3149518 https://reactome.org/PathwayBrowser/#/R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl TAS Homo sapiens 16304 R-HSA-3149519 https://reactome.org/PathwayBrowser/#/R-HSA-3149519 MMACHC decyanates CNCbl TAS Homo sapiens 16304 R-HSA-3149563 https://reactome.org/PathwayBrowser/#/R-HSA-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria TAS Homo sapiens 16304 R-HSA-3159253 https://reactome.org/PathwayBrowser/#/R-HSA-3159253 MMAB adenosylates cob(I)alamin TAS Homo sapiens 16304 R-HSA-3204318 https://reactome.org/PathwayBrowser/#/R-HSA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR TAS Homo sapiens 16304 R-HSA-3318563 https://reactome.org/PathwayBrowser/#/R-HSA-3318563 Defective MTRR does not convert cob(II)alamin to MeCbl TAS Homo sapiens 16304 R-HSA-3318571 https://reactome.org/PathwayBrowser/#/R-HSA-3318571 Defective MMADHC does not bind MMACHC:B12r TAS Homo sapiens 16304 R-HSA-9759549 https://reactome.org/PathwayBrowser/#/R-HSA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin TAS Homo sapiens 16304 R-MMU-3149494 https://reactome.org/PathwayBrowser/#/R-MMU-3149494 MMACHC:cob(II)alamin binds MMADHC IEA Mus musculus 16304 R-MMU-3149518 https://reactome.org/PathwayBrowser/#/R-MMU-3149518 MTRR reduces cob(II)alamin to meCbl IEA Mus musculus 16304 R-MMU-3149519 https://reactome.org/PathwayBrowser/#/R-MMU-3149519 MMACHC decyanates CNCbl IEA Mus musculus 16304 R-MMU-3149563 https://reactome.org/PathwayBrowser/#/R-MMU-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria IEA Mus musculus 16304 R-MMU-3159253 https://reactome.org/PathwayBrowser/#/R-MMU-3159253 MMAB adenosylates cob(I)alamin IEA Mus musculus 16304 R-MMU-3204318 https://reactome.org/PathwayBrowser/#/R-MMU-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Mus musculus 16304 R-MMU-9759549 https://reactome.org/PathwayBrowser/#/R-MMU-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Mus musculus 16304 R-RNO-3149494 https://reactome.org/PathwayBrowser/#/R-RNO-3149494 MMACHC:cob(II)alamin binds MMADHC IEA Rattus norvegicus 16304 R-RNO-3149518 https://reactome.org/PathwayBrowser/#/R-RNO-3149518 MTRR reduces cob(II)alamin to meCbl IEA Rattus norvegicus 16304 R-RNO-3149519 https://reactome.org/PathwayBrowser/#/R-RNO-3149519 MMACHC decyanates CNCbl IEA Rattus norvegicus 16304 R-RNO-3149563 https://reactome.org/PathwayBrowser/#/R-RNO-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria IEA Rattus norvegicus 16304 R-RNO-3159253 https://reactome.org/PathwayBrowser/#/R-RNO-3159253 MMAB adenosylates cob(I)alamin IEA Rattus norvegicus 16304 R-RNO-3204318 https://reactome.org/PathwayBrowser/#/R-RNO-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Rattus norvegicus 16304 R-RNO-9759549 https://reactome.org/PathwayBrowser/#/R-RNO-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Rattus norvegicus 16304 R-SSC-3149494 https://reactome.org/PathwayBrowser/#/R-SSC-3149494 MMACHC:cob(II)alamin binds MMADHC IEA Sus scrofa 16304 R-SSC-3149518 https://reactome.org/PathwayBrowser/#/R-SSC-3149518 MTRR reduces cob(II)alamin to meCbl IEA Sus scrofa 16304 R-SSC-3149519 https://reactome.org/PathwayBrowser/#/R-SSC-3149519 MMACHC decyanates CNCbl IEA Sus scrofa 16304 R-SSC-3149563 https://reactome.org/PathwayBrowser/#/R-SSC-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria IEA Sus scrofa 16304 R-SSC-3159253 https://reactome.org/PathwayBrowser/#/R-SSC-3159253 MMAB adenosylates cob(I)alamin IEA Sus scrofa 16304 R-SSC-3204318 https://reactome.org/PathwayBrowser/#/R-SSC-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Sus scrofa 16304 R-SSC-9759549 https://reactome.org/PathwayBrowser/#/R-SSC-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Sus scrofa 16304 R-XTR-3149494 https://reactome.org/PathwayBrowser/#/R-XTR-3149494 MMACHC:cob(II)alamin binds MMADHC IEA Xenopus tropicalis 16304 R-XTR-3149519 https://reactome.org/PathwayBrowser/#/R-XTR-3149519 MMACHC decyanates CNCbl IEA Xenopus tropicalis 16304 R-XTR-3149563 https://reactome.org/PathwayBrowser/#/R-XTR-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria IEA Xenopus tropicalis 16304 R-XTR-3159253 https://reactome.org/PathwayBrowser/#/R-XTR-3159253 MMAB adenosylates cob(I)alamin IEA Xenopus tropicalis 16304 R-XTR-9759549 https://reactome.org/PathwayBrowser/#/R-XTR-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Xenopus tropicalis 16330 R-BTA-469659 https://reactome.org/PathwayBrowser/#/R-BTA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Bos taurus 16330 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 16330 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 16330 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 16330 R-BTA-5625717 https://reactome.org/PathwayBrowser/#/R-BTA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Bos taurus 16330 R-BTA-5625738 https://reactome.org/PathwayBrowser/#/R-BTA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Bos taurus 16330 R-BTA-5625745 https://reactome.org/PathwayBrowser/#/R-BTA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Bos taurus 16330 R-BTA-5625774 https://reactome.org/PathwayBrowser/#/R-BTA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Bos taurus 16330 R-BTA-5625784 https://reactome.org/PathwayBrowser/#/R-BTA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Bos taurus 16330 R-BTA-5625796 https://reactome.org/PathwayBrowser/#/R-BTA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Bos taurus 16330 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 16330 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 16330 R-BTA-5625849 https://reactome.org/PathwayBrowser/#/R-BTA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Bos taurus 16330 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 16330 R-BTA-8877902 https://reactome.org/PathwayBrowser/#/R-BTA-8877902 Activated AR binds RUNX2 IEA Bos taurus 16330 R-BTA-9705713 https://reactome.org/PathwayBrowser/#/R-BTA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Bos taurus 16330 R-BTA-9705714 https://reactome.org/PathwayBrowser/#/R-BTA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Bos taurus 16330 R-BTA-9705925 https://reactome.org/PathwayBrowser/#/R-BTA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Bos taurus 16330 R-CEL-469659 https://reactome.org/PathwayBrowser/#/R-CEL-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 16330 R-CEL-9705713 https://reactome.org/PathwayBrowser/#/R-CEL-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 16330 R-CEL-9705714 https://reactome.org/PathwayBrowser/#/R-CEL-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 16330 R-CFA-469659 https://reactome.org/PathwayBrowser/#/R-CFA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Canis familiaris 16330 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 16330 R-CFA-5625717 https://reactome.org/PathwayBrowser/#/R-CFA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Canis familiaris 16330 R-CFA-5625738 https://reactome.org/PathwayBrowser/#/R-CFA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Canis familiaris 16330 R-CFA-5625745 https://reactome.org/PathwayBrowser/#/R-CFA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Canis familiaris 16330 R-CFA-5625774 https://reactome.org/PathwayBrowser/#/R-CFA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Canis familiaris 16330 R-CFA-5625784 https://reactome.org/PathwayBrowser/#/R-CFA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Canis familiaris 16330 R-CFA-5625796 https://reactome.org/PathwayBrowser/#/R-CFA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Canis familiaris 16330 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 16330 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 16330 R-CFA-5625849 https://reactome.org/PathwayBrowser/#/R-CFA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Canis familiaris 16330 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 16330 R-CFA-8877902 https://reactome.org/PathwayBrowser/#/R-CFA-8877902 Activated AR binds RUNX2 IEA Canis familiaris 16330 R-CFA-9705713 https://reactome.org/PathwayBrowser/#/R-CFA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Canis familiaris 16330 R-CFA-9705714 https://reactome.org/PathwayBrowser/#/R-CFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Canis familiaris 16330 R-CFA-9705925 https://reactome.org/PathwayBrowser/#/R-CFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Canis familiaris 16330 R-DDI-5625784 https://reactome.org/PathwayBrowser/#/R-DDI-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Dictyostelium discoideum 16330 R-DDI-9705714 https://reactome.org/PathwayBrowser/#/R-DDI-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Dictyostelium discoideum 16330 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 16330 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 16330 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 16330 R-DME-5625717 https://reactome.org/PathwayBrowser/#/R-DME-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Drosophila melanogaster 16330 R-DME-5625738 https://reactome.org/PathwayBrowser/#/R-DME-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Drosophila melanogaster 16330 R-DME-5625745 https://reactome.org/PathwayBrowser/#/R-DME-5625745 PKN1 stimulates association of AR with NCOA2 IEA Drosophila melanogaster 16330 R-DME-5625774 https://reactome.org/PathwayBrowser/#/R-DME-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Drosophila melanogaster 16330 R-DME-5625784 https://reactome.org/PathwayBrowser/#/R-DME-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Drosophila melanogaster 16330 R-DME-5625796 https://reactome.org/PathwayBrowser/#/R-DME-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 16330 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 16330 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 16330 R-DME-5625849 https://reactome.org/PathwayBrowser/#/R-DME-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 16330 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 16330 R-DME-8877902 https://reactome.org/PathwayBrowser/#/R-DME-8877902 Activated AR binds RUNX2 IEA Drosophila melanogaster 16330 R-DME-9705714 https://reactome.org/PathwayBrowser/#/R-DME-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Drosophila melanogaster 16330 R-DME-9705925 https://reactome.org/PathwayBrowser/#/R-DME-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Drosophila melanogaster 16330 R-DRE-469659 https://reactome.org/PathwayBrowser/#/R-DRE-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Danio rerio 16330 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 16330 R-DRE-5625717 https://reactome.org/PathwayBrowser/#/R-DRE-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Danio rerio 16330 R-DRE-5625738 https://reactome.org/PathwayBrowser/#/R-DRE-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Danio rerio 16330 R-DRE-5625745 https://reactome.org/PathwayBrowser/#/R-DRE-5625745 PKN1 stimulates association of AR with NCOA2 IEA Danio rerio 16330 R-DRE-5625774 https://reactome.org/PathwayBrowser/#/R-DRE-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Danio rerio 16330 R-DRE-5625784 https://reactome.org/PathwayBrowser/#/R-DRE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Danio rerio 16330 R-DRE-5625796 https://reactome.org/PathwayBrowser/#/R-DRE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Danio rerio 16330 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 16330 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 16330 R-DRE-8877902 https://reactome.org/PathwayBrowser/#/R-DRE-8877902 Activated AR binds RUNX2 IEA Danio rerio 16330 R-DRE-9705713 https://reactome.org/PathwayBrowser/#/R-DRE-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Danio rerio 16330 R-DRE-9705714 https://reactome.org/PathwayBrowser/#/R-DRE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Danio rerio 16330 R-DRE-9705925 https://reactome.org/PathwayBrowser/#/R-DRE-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Danio rerio 16330 R-GGA-469659 https://reactome.org/PathwayBrowser/#/R-GGA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Gallus gallus 16330 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 16330 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 16330 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 16330 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus 16330 R-GGA-5625796 https://reactome.org/PathwayBrowser/#/R-GGA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Gallus gallus 16330 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 16330 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 16330 R-GGA-5625849 https://reactome.org/PathwayBrowser/#/R-GGA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Gallus gallus 16330 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 16330 R-GGA-8877902 https://reactome.org/PathwayBrowser/#/R-GGA-8877902 Activated AR binds RUNX2 IEA Gallus gallus 16330 R-GGA-9705713 https://reactome.org/PathwayBrowser/#/R-GGA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Gallus gallus 16330 R-GGA-9705714 https://reactome.org/PathwayBrowser/#/R-GGA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Gallus gallus 16330 R-GGA-9705925 https://reactome.org/PathwayBrowser/#/R-GGA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Gallus gallus 16330 R-HSA-469659 https://reactome.org/PathwayBrowser/#/R-HSA-469659 SRD5A1 dehydrogenates TEST to DHTEST TAS Homo sapiens 16330 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 16330 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 16330 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 16330 R-HSA-5625717 https://reactome.org/PathwayBrowser/#/R-HSA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) TAS Homo sapiens 16330 R-HSA-5625738 https://reactome.org/PathwayBrowser/#/R-HSA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus TAS Homo sapiens 16330 R-HSA-5625745 https://reactome.org/PathwayBrowser/#/R-HSA-5625745 PKN1 stimulates association of AR with NCOA2 TAS Homo sapiens 16330 R-HSA-5625774 https://reactome.org/PathwayBrowser/#/R-HSA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes TAS Homo sapiens 16330 R-HSA-5625784 https://reactome.org/PathwayBrowser/#/R-HSA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters TAS Homo sapiens 16330 R-HSA-5625796 https://reactome.org/PathwayBrowser/#/R-HSA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters TAS Homo sapiens 16330 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 16330 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 16330 R-HSA-5625849 https://reactome.org/PathwayBrowser/#/R-HSA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters TAS Homo sapiens 16330 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 16330 R-HSA-5625883 https://reactome.org/PathwayBrowser/#/R-HSA-5625883 PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 TAS Homo sapiens 16330 R-HSA-8877902 https://reactome.org/PathwayBrowser/#/R-HSA-8877902 Activated AR binds RUNX2 TAS Homo sapiens 16330 R-HSA-8877918 https://reactome.org/PathwayBrowser/#/R-HSA-8877918 RUNX2:MAF complex binds the BGLAP gene promoter IEA Homo sapiens 16330 R-HSA-9705713 https://reactome.org/PathwayBrowser/#/R-HSA-9705713 SRD5A2 dehydrogenates TEST to DHTEST TAS Homo sapiens 16330 R-HSA-9705714 https://reactome.org/PathwayBrowser/#/R-HSA-9705714 SRD5A3 dehydrogenates TEST to DHTEST TAS Homo sapiens 16330 R-HSA-9705925 https://reactome.org/PathwayBrowser/#/R-HSA-9705925 Androgens binds AR (in the HSP90 chaperone complex) TAS Homo sapiens 16330 R-MMU-469659 https://reactome.org/PathwayBrowser/#/R-MMU-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Mus musculus 16330 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 16330 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 16330 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 16330 R-MMU-5625717 https://reactome.org/PathwayBrowser/#/R-MMU-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Mus musculus 16330 R-MMU-5625738 https://reactome.org/PathwayBrowser/#/R-MMU-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Mus musculus 16330 R-MMU-5625745 https://reactome.org/PathwayBrowser/#/R-MMU-5625745 PKN1 stimulates association of AR with NCOA2 IEA Mus musculus 16330 R-MMU-8877902 https://reactome.org/PathwayBrowser/#/R-MMU-8877902 Activated AR binds RUNX2 IEA Mus musculus 16330 R-MMU-9705713 https://reactome.org/PathwayBrowser/#/R-MMU-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Mus musculus 16330 R-MMU-9705714 https://reactome.org/PathwayBrowser/#/R-MMU-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Mus musculus 16330 R-MMU-9705925 https://reactome.org/PathwayBrowser/#/R-MMU-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Mus musculus 16330 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 16330 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 16330 R-PFA-9705714 https://reactome.org/PathwayBrowser/#/R-PFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Plasmodium falciparum 16330 R-PFA-9705925 https://reactome.org/PathwayBrowser/#/R-PFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Plasmodium falciparum 16330 R-RNO-469659 https://reactome.org/PathwayBrowser/#/R-RNO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 16330 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 16330 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 16330 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 16330 R-RNO-5625717 https://reactome.org/PathwayBrowser/#/R-RNO-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Rattus norvegicus 16330 R-RNO-5625738 https://reactome.org/PathwayBrowser/#/R-RNO-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Rattus norvegicus 16330 R-RNO-5625745 https://reactome.org/PathwayBrowser/#/R-RNO-5625745 PKN1 stimulates association of AR with NCOA2 IEA Rattus norvegicus 16330 R-RNO-5625774 https://reactome.org/PathwayBrowser/#/R-RNO-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Rattus norvegicus 16330 R-RNO-5625784 https://reactome.org/PathwayBrowser/#/R-RNO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Rattus norvegicus 16330 R-RNO-5625796 https://reactome.org/PathwayBrowser/#/R-RNO-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Rattus norvegicus 16330 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 16330 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 16330 R-RNO-5625849 https://reactome.org/PathwayBrowser/#/R-RNO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Rattus norvegicus 16330 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 16330 R-RNO-9705713 https://reactome.org/PathwayBrowser/#/R-RNO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 16330 R-RNO-9705714 https://reactome.org/PathwayBrowser/#/R-RNO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 16330 R-RNO-9705925 https://reactome.org/PathwayBrowser/#/R-RNO-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Rattus norvegicus 16330 R-SCE-5625784 https://reactome.org/PathwayBrowser/#/R-SCE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16330 R-SCE-5625796 https://reactome.org/PathwayBrowser/#/R-SCE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16330 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16330 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16330 R-SCE-5625849 https://reactome.org/PathwayBrowser/#/R-SCE-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16330 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16330 R-SCE-9705714 https://reactome.org/PathwayBrowser/#/R-SCE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Saccharomyces cerevisiae 16330 R-SPO-469659 https://reactome.org/PathwayBrowser/#/R-SPO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 16330 R-SPO-5625784 https://reactome.org/PathwayBrowser/#/R-SPO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16330 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16330 R-SPO-5625849 https://reactome.org/PathwayBrowser/#/R-SPO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16330 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16330 R-SPO-9705713 https://reactome.org/PathwayBrowser/#/R-SPO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 16330 R-SPO-9705714 https://reactome.org/PathwayBrowser/#/R-SPO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 16330 R-SSC-469659 https://reactome.org/PathwayBrowser/#/R-SSC-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Sus scrofa 16330 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 16330 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 16330 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 16330 R-SSC-5625717 https://reactome.org/PathwayBrowser/#/R-SSC-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Sus scrofa 16330 R-SSC-5625738 https://reactome.org/PathwayBrowser/#/R-SSC-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Sus scrofa 16330 R-SSC-5625745 https://reactome.org/PathwayBrowser/#/R-SSC-5625745 PKN1 stimulates association of AR with NCOA2 IEA Sus scrofa 16330 R-SSC-5625774 https://reactome.org/PathwayBrowser/#/R-SSC-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Sus scrofa 16330 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa 16330 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa 16330 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 16330 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 16330 R-SSC-5625849 https://reactome.org/PathwayBrowser/#/R-SSC-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Sus scrofa 16330 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 16330 R-SSC-8877902 https://reactome.org/PathwayBrowser/#/R-SSC-8877902 Activated AR binds RUNX2 IEA Sus scrofa 16330 R-SSC-9705713 https://reactome.org/PathwayBrowser/#/R-SSC-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Sus scrofa 16330 R-SSC-9705714 https://reactome.org/PathwayBrowser/#/R-SSC-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Sus scrofa 16330 R-SSC-9705925 https://reactome.org/PathwayBrowser/#/R-SSC-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Sus scrofa 16330 R-XTR-469659 https://reactome.org/PathwayBrowser/#/R-XTR-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 16330 R-XTR-8877902 https://reactome.org/PathwayBrowser/#/R-XTR-8877902 Activated AR binds RUNX2 IEA Xenopus tropicalis 16330 R-XTR-9705713 https://reactome.org/PathwayBrowser/#/R-XTR-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 16330 R-XTR-9705714 https://reactome.org/PathwayBrowser/#/R-XTR-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 16330 R-XTR-9705925 https://reactome.org/PathwayBrowser/#/R-XTR-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Xenopus tropicalis 16335 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 16335 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 16335 R-BTA-109415 https://reactome.org/PathwayBrowser/#/R-BTA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Bos taurus 16335 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16335 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16335 R-BTA-109530 https://reactome.org/PathwayBrowser/#/R-BTA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Bos taurus 16335 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 16335 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 16335 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 16335 R-BTA-109539 https://reactome.org/PathwayBrowser/#/R-BTA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Bos taurus 16335 R-BTA-109624 https://reactome.org/PathwayBrowser/#/R-BTA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Bos taurus 16335 R-BTA-174401 https://reactome.org/PathwayBrowser/#/R-BTA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Bos taurus 16335 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 16335 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 16335 R-BTA-418904 https://reactome.org/PathwayBrowser/#/R-BTA-418904 A1 and A3 receptors bind adenosine IEA Bos taurus 16335 R-BTA-418925 https://reactome.org/PathwayBrowser/#/R-BTA-418925 ADORA2A,B bind Ade-Rib IEA Bos taurus 16335 R-BTA-5684862 https://reactome.org/PathwayBrowser/#/R-BTA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Bos taurus 16335 R-BTA-5693346 https://reactome.org/PathwayBrowser/#/R-BTA-5693346 CECRI deaminates Ade-Rib to Ino IEA Bos taurus 16335 R-BTA-727740 https://reactome.org/PathwayBrowser/#/R-BTA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 16335 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 16335 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 16335 R-BTA-727768 https://reactome.org/PathwayBrowser/#/R-BTA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 16335 R-BTA-74241 https://reactome.org/PathwayBrowser/#/R-BTA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Bos taurus 16335 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 16335 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 16335 R-BTA-8857692 https://reactome.org/PathwayBrowser/#/R-BTA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Bos taurus 16335 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16335 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16335 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans 16335 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 16335 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 16335 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 16335 R-CEL-109539 https://reactome.org/PathwayBrowser/#/R-CEL-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Caenorhabditis elegans 16335 R-CEL-109624 https://reactome.org/PathwayBrowser/#/R-CEL-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Caenorhabditis elegans 16335 R-CEL-174401 https://reactome.org/PathwayBrowser/#/R-CEL-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Caenorhabditis elegans 16335 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 16335 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 16335 R-CEL-418904 https://reactome.org/PathwayBrowser/#/R-CEL-418904 A1 and A3 receptors bind adenosine IEA Caenorhabditis elegans 16335 R-CEL-418925 https://reactome.org/PathwayBrowser/#/R-CEL-418925 ADORA2A,B bind Ade-Rib IEA Caenorhabditis elegans 16335 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 16335 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 16335 R-CEL-74241 https://reactome.org/PathwayBrowser/#/R-CEL-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Caenorhabditis elegans 16335 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 16335 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 16335 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 16335 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 16335 R-CFA-109415 https://reactome.org/PathwayBrowser/#/R-CFA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Canis familiaris 16335 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16335 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16335 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 16335 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 16335 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 16335 R-CFA-109624 https://reactome.org/PathwayBrowser/#/R-CFA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Canis familiaris 16335 R-CFA-174401 https://reactome.org/PathwayBrowser/#/R-CFA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Canis familiaris 16335 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 16335 R-CFA-418904 https://reactome.org/PathwayBrowser/#/R-CFA-418904 A1 and A3 receptors bind adenosine IEA Canis familiaris 16335 R-CFA-418925 https://reactome.org/PathwayBrowser/#/R-CFA-418925 ADORA2A,B bind Ade-Rib IEA Canis familiaris 16335 R-CFA-5684862 https://reactome.org/PathwayBrowser/#/R-CFA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Canis familiaris 16335 R-CFA-727740 https://reactome.org/PathwayBrowser/#/R-CFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 16335 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 16335 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 16335 R-CFA-727768 https://reactome.org/PathwayBrowser/#/R-CFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 16335 R-CFA-74241 https://reactome.org/PathwayBrowser/#/R-CFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Canis familiaris 16335 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 16335 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 16335 R-CFA-8857692 https://reactome.org/PathwayBrowser/#/R-CFA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Canis familiaris 16335 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16335 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16335 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 16335 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 16335 R-DDI-109624 https://reactome.org/PathwayBrowser/#/R-DDI-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Dictyostelium discoideum 16335 R-DDI-174401 https://reactome.org/PathwayBrowser/#/R-DDI-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Dictyostelium discoideum 16335 R-DDI-5693346 https://reactome.org/PathwayBrowser/#/R-DDI-5693346 CECRI deaminates Ade-Rib to Ino IEA Dictyostelium discoideum 16335 R-DDI-727740 https://reactome.org/PathwayBrowser/#/R-DDI-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 16335 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 16335 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 16335 R-DDI-727768 https://reactome.org/PathwayBrowser/#/R-DDI-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 16335 R-DDI-74241 https://reactome.org/PathwayBrowser/#/R-DDI-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Dictyostelium discoideum 16335 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 16335 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16335 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16335 R-DME-109530 https://reactome.org/PathwayBrowser/#/R-DME-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Drosophila melanogaster 16335 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 16335 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 16335 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 16335 R-DME-109539 https://reactome.org/PathwayBrowser/#/R-DME-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Drosophila melanogaster 16335 R-DME-109624 https://reactome.org/PathwayBrowser/#/R-DME-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Drosophila melanogaster 16335 R-DME-174401 https://reactome.org/PathwayBrowser/#/R-DME-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Drosophila melanogaster 16335 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 16335 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 16335 R-DME-418904 https://reactome.org/PathwayBrowser/#/R-DME-418904 A1 and A3 receptors bind adenosine IEA Drosophila melanogaster 16335 R-DME-418925 https://reactome.org/PathwayBrowser/#/R-DME-418925 ADORA2A,B bind Ade-Rib IEA Drosophila melanogaster 16335 R-DME-5693346 https://reactome.org/PathwayBrowser/#/R-DME-5693346 CECRI deaminates Ade-Rib to Ino IEA Drosophila melanogaster 16335 R-DME-727740 https://reactome.org/PathwayBrowser/#/R-DME-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 16335 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 16335 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 16335 R-DME-727768 https://reactome.org/PathwayBrowser/#/R-DME-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 16335 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 16335 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 16335 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 16335 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 16335 R-DRE-109415 https://reactome.org/PathwayBrowser/#/R-DRE-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Danio rerio 16335 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 16335 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 16335 R-DRE-109624 https://reactome.org/PathwayBrowser/#/R-DRE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Danio rerio 16335 R-DRE-174401 https://reactome.org/PathwayBrowser/#/R-DRE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Danio rerio 16335 R-DRE-418925 https://reactome.org/PathwayBrowser/#/R-DRE-418925 ADORA2A,B bind Ade-Rib IEA Danio rerio 16335 R-DRE-5693346 https://reactome.org/PathwayBrowser/#/R-DRE-5693346 CECRI deaminates Ade-Rib to Ino IEA Danio rerio 16335 R-DRE-727740 https://reactome.org/PathwayBrowser/#/R-DRE-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 16335 R-DRE-727768 https://reactome.org/PathwayBrowser/#/R-DRE-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 16335 R-DRE-74241 https://reactome.org/PathwayBrowser/#/R-DRE-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Danio rerio 16335 R-DRE-8857692 https://reactome.org/PathwayBrowser/#/R-DRE-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Danio rerio 16335 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 16335 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 16335 R-GGA-109415 https://reactome.org/PathwayBrowser/#/R-GGA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Gallus gallus 16335 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 16335 R-GGA-109539 https://reactome.org/PathwayBrowser/#/R-GGA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Gallus gallus 16335 R-GGA-109624 https://reactome.org/PathwayBrowser/#/R-GGA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Gallus gallus 16335 R-GGA-174401 https://reactome.org/PathwayBrowser/#/R-GGA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Gallus gallus 16335 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 16335 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 16335 R-GGA-418904 https://reactome.org/PathwayBrowser/#/R-GGA-418904 A1 and A3 receptors bind adenosine IEA Gallus gallus 16335 R-GGA-418925 https://reactome.org/PathwayBrowser/#/R-GGA-418925 ADORA2A,B bind Ade-Rib IEA Gallus gallus 16335 R-GGA-5684862 https://reactome.org/PathwayBrowser/#/R-GGA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Gallus gallus 16335 R-GGA-5693346 https://reactome.org/PathwayBrowser/#/R-GGA-5693346 CECRI deaminates Ade-Rib to Ino IEA Gallus gallus 16335 R-GGA-727740 https://reactome.org/PathwayBrowser/#/R-GGA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 16335 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 16335 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 16335 R-GGA-727768 https://reactome.org/PathwayBrowser/#/R-GGA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 16335 R-GGA-74241 https://reactome.org/PathwayBrowser/#/R-GGA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Gallus gallus 16335 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 16335 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 16335 R-GGA-8857692 https://reactome.org/PathwayBrowser/#/R-GGA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Gallus gallus 16335 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 16335 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 16335 R-HSA-109415 https://reactome.org/PathwayBrowser/#/R-HSA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] TAS Homo sapiens 16335 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16335 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16335 R-HSA-109530 https://reactome.org/PathwayBrowser/#/R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 TAS Homo sapiens 16335 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 16335 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 16335 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 16335 R-HSA-109539 https://reactome.org/PathwayBrowser/#/R-HSA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 TAS Homo sapiens 16335 R-HSA-109624 https://reactome.org/PathwayBrowser/#/R-HSA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) TAS Homo sapiens 16335 R-HSA-174401 https://reactome.org/PathwayBrowser/#/R-HSA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy TAS Homo sapiens 16335 R-HSA-187661 https://reactome.org/PathwayBrowser/#/R-HSA-187661 Ade-Rib binds AODORA2A and NTRK1,2 IEA Homo sapiens 16335 R-HSA-2161193 https://reactome.org/PathwayBrowser/#/R-HSA-2161193 abacavir + AMP => abacavir monophosphate + adenosine TAS Homo sapiens 16335 R-HSA-2408532 https://reactome.org/PathwayBrowser/#/R-HSA-2408532 AdeSeHCys is hydrolysed to SeHCys by AHCY IEA Homo sapiens 16335 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 16335 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 16335 R-HSA-418904 https://reactome.org/PathwayBrowser/#/R-HSA-418904 A1 and A3 receptors bind adenosine TAS Homo sapiens 16335 R-HSA-418925 https://reactome.org/PathwayBrowser/#/R-HSA-418925 ADORA2A,B bind Ade-Rib TAS Homo sapiens 16335 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 16335 R-HSA-5684862 https://reactome.org/PathwayBrowser/#/R-HSA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. TAS Homo sapiens 16335 R-HSA-5693346 https://reactome.org/PathwayBrowser/#/R-HSA-5693346 CECRI deaminates Ade-Rib to Ino TAS Homo sapiens 16335 R-HSA-727740 https://reactome.org/PathwayBrowser/#/R-HSA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 16335 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 16335 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 16335 R-HSA-727768 https://reactome.org/PathwayBrowser/#/R-HSA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 16335 R-HSA-74241 https://reactome.org/PathwayBrowser/#/R-HSA-74241 ADA catalyzes the deamination of (deoxy)adenosine TAS Homo sapiens 16335 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 16335 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 16335 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 16335 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 16335 R-HSA-8857692 https://reactome.org/PathwayBrowser/#/R-HSA-8857692 RNA demethylases demethylate N6-methyladenosine RNA TAS Homo sapiens 16335 R-HSA-9613023 https://reactome.org/PathwayBrowser/#/R-HSA-9613023 NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates IEA Homo sapiens 16335 R-HSA-9660819 https://reactome.org/PathwayBrowser/#/R-HSA-9660819 ADORA2B:Ade-Rib:GsGTP dissociates TAS Homo sapiens 16335 R-HSA-9660824 https://reactome.org/PathwayBrowser/#/R-HSA-9660824 ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs TAS Homo sapiens 16335 R-HSA-9660828 https://reactome.org/PathwayBrowser/#/R-HSA-9660828 ADORA2B:Ade-Rib binds heterometric G-protein Gs TAS Homo sapiens 16335 R-HSA-9660829 https://reactome.org/PathwayBrowser/#/R-HSA-9660829 ADORA2B binds Ade-Rib TAS Homo sapiens 16335 R-HSA-9734745 https://reactome.org/PathwayBrowser/#/R-HSA-9734745 Defective ADA does not deaminate (deoxy)adenosine TAS Homo sapiens 16335 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 16335 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 16335 R-MMU-109415 https://reactome.org/PathwayBrowser/#/R-MMU-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Mus musculus 16335 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16335 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16335 R-MMU-109530 https://reactome.org/PathwayBrowser/#/R-MMU-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Mus musculus 16335 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 16335 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 16335 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 16335 R-MMU-109539 https://reactome.org/PathwayBrowser/#/R-MMU-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Mus musculus 16335 R-MMU-109624 https://reactome.org/PathwayBrowser/#/R-MMU-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Mus musculus 16335 R-MMU-174401 https://reactome.org/PathwayBrowser/#/R-MMU-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Mus musculus 16335 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 16335 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 16335 R-MMU-418904 https://reactome.org/PathwayBrowser/#/R-MMU-418904 A1 and A3 receptors bind adenosine IEA Mus musculus 16335 R-MMU-418925 https://reactome.org/PathwayBrowser/#/R-MMU-418925 ADORA2A,B bind Ade-Rib IEA Mus musculus 16335 R-MMU-5684862 https://reactome.org/PathwayBrowser/#/R-MMU-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Mus musculus 16335 R-MMU-727740 https://reactome.org/PathwayBrowser/#/R-MMU-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 16335 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 16335 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 16335 R-MMU-727768 https://reactome.org/PathwayBrowser/#/R-MMU-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 16335 R-MMU-74241 https://reactome.org/PathwayBrowser/#/R-MMU-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Mus musculus 16335 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 16335 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 16335 R-MMU-8857692 https://reactome.org/PathwayBrowser/#/R-MMU-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Mus musculus 16335 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16335 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16335 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 16335 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 16335 R-PFA-727740 https://reactome.org/PathwayBrowser/#/R-PFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 16335 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 16335 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 16335 R-PFA-727768 https://reactome.org/PathwayBrowser/#/R-PFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 16335 R-PFA-74241 https://reactome.org/PathwayBrowser/#/R-PFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Plasmodium falciparum 16335 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 16335 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 16335 R-RNO-109415 https://reactome.org/PathwayBrowser/#/R-RNO-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Rattus norvegicus 16335 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16335 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16335 R-RNO-109530 https://reactome.org/PathwayBrowser/#/R-RNO-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Rattus norvegicus 16335 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 16335 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 16335 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 16335 R-RNO-109539 https://reactome.org/PathwayBrowser/#/R-RNO-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Rattus norvegicus 16335 R-RNO-109624 https://reactome.org/PathwayBrowser/#/R-RNO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Rattus norvegicus 16335 R-RNO-174401 https://reactome.org/PathwayBrowser/#/R-RNO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Rattus norvegicus 16335 R-RNO-189618 https://reactome.org/PathwayBrowser/#/R-RNO-189618 TrkA activation by adenosine A2a receptor TAS Rattus norvegicus 16335 R-RNO-2408512 https://reactome.org/PathwayBrowser/#/R-RNO-2408512 AdeSeHCys is hydrolysed to SeHCys by Ahcy TAS Rattus norvegicus 16335 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 16335 R-RNO-418904 https://reactome.org/PathwayBrowser/#/R-RNO-418904 A1 and A3 receptors bind adenosine IEA Rattus norvegicus 16335 R-RNO-418925 https://reactome.org/PathwayBrowser/#/R-RNO-418925 ADORA2A,B bind Ade-Rib IEA Rattus norvegicus 16335 R-RNO-5684862 https://reactome.org/PathwayBrowser/#/R-RNO-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Rattus norvegicus 16335 R-RNO-727740 https://reactome.org/PathwayBrowser/#/R-RNO-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 16335 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 16335 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 16335 R-RNO-727768 https://reactome.org/PathwayBrowser/#/R-RNO-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 16335 R-RNO-74241 https://reactome.org/PathwayBrowser/#/R-RNO-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Rattus norvegicus 16335 R-RNO-8857692 https://reactome.org/PathwayBrowser/#/R-RNO-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Rattus norvegicus 16335 R-RNO-9613030 https://reactome.org/PathwayBrowser/#/R-RNO-9613030 Ntrk1,2,3 in Ade-Rib:Adora2a:Ntrk1,2,3 autophosphorylates TAS Rattus norvegicus 16335 R-SCE-109624 https://reactome.org/PathwayBrowser/#/R-SCE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Saccharomyces cerevisiae 16335 R-SCE-174401 https://reactome.org/PathwayBrowser/#/R-SCE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Saccharomyces cerevisiae 16335 R-SPO-109624 https://reactome.org/PathwayBrowser/#/R-SPO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Schizosaccharomyces pombe 16335 R-SPO-174401 https://reactome.org/PathwayBrowser/#/R-SPO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Schizosaccharomyces pombe 16335 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 16335 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 16335 R-SSC-109415 https://reactome.org/PathwayBrowser/#/R-SSC-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Sus scrofa 16335 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16335 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16335 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa 16335 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 16335 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 16335 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 16335 R-SSC-109539 https://reactome.org/PathwayBrowser/#/R-SSC-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Sus scrofa 16335 R-SSC-109624 https://reactome.org/PathwayBrowser/#/R-SSC-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Sus scrofa 16335 R-SSC-174401 https://reactome.org/PathwayBrowser/#/R-SSC-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Sus scrofa 16335 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 16335 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 16335 R-SSC-418904 https://reactome.org/PathwayBrowser/#/R-SSC-418904 A1 and A3 receptors bind adenosine IEA Sus scrofa 16335 R-SSC-418925 https://reactome.org/PathwayBrowser/#/R-SSC-418925 ADORA2A,B bind Ade-Rib IEA Sus scrofa 16335 R-SSC-5684862 https://reactome.org/PathwayBrowser/#/R-SSC-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Sus scrofa 16335 R-SSC-5693346 https://reactome.org/PathwayBrowser/#/R-SSC-5693346 CECRI deaminates Ade-Rib to Ino IEA Sus scrofa 16335 R-SSC-727740 https://reactome.org/PathwayBrowser/#/R-SSC-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 16335 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 16335 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 16335 R-SSC-727768 https://reactome.org/PathwayBrowser/#/R-SSC-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 16335 R-SSC-74241 https://reactome.org/PathwayBrowser/#/R-SSC-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Sus scrofa 16335 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 16335 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 16335 R-SSC-8857692 https://reactome.org/PathwayBrowser/#/R-SSC-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Sus scrofa 16335 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 16335 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 16335 R-XTR-109415 https://reactome.org/PathwayBrowser/#/R-XTR-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Xenopus tropicalis 16335 R-XTR-109530 https://reactome.org/PathwayBrowser/#/R-XTR-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Xenopus tropicalis 16335 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 16335 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 16335 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 16335 R-XTR-109539 https://reactome.org/PathwayBrowser/#/R-XTR-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Xenopus tropicalis 16335 R-XTR-109624 https://reactome.org/PathwayBrowser/#/R-XTR-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Xenopus tropicalis 16335 R-XTR-174401 https://reactome.org/PathwayBrowser/#/R-XTR-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Xenopus tropicalis 16335 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 16335 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 16335 R-XTR-418925 https://reactome.org/PathwayBrowser/#/R-XTR-418925 ADORA2A,B bind Ade-Rib IEA Xenopus tropicalis 16335 R-XTR-5693346 https://reactome.org/PathwayBrowser/#/R-XTR-5693346 CECRI deaminates Ade-Rib to Ino IEA Xenopus tropicalis 16335 R-XTR-74241 https://reactome.org/PathwayBrowser/#/R-XTR-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Xenopus tropicalis 16335 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 16335 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 16335 R-XTR-8857692 https://reactome.org/PathwayBrowser/#/R-XTR-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Xenopus tropicalis 16336 R-BTA-1306876 https://reactome.org/PathwayBrowser/#/R-BTA-1306876 NLRP3 activation by small molecules IEA Bos taurus 16336 R-BTA-2142859 https://reactome.org/PathwayBrowser/#/R-BTA-2142859 Growing HA is extruded from the cell by ABCC5 IEA Bos taurus 16336 R-BTA-2160884 https://reactome.org/PathwayBrowser/#/R-BTA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Bos taurus 16336 R-BTA-2160892 https://reactome.org/PathwayBrowser/#/R-BTA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Bos taurus 16336 R-BTA-2160915 https://reactome.org/PathwayBrowser/#/R-BTA-2160915 Receptor-mediated uptake of HA IEA Bos taurus 16336 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 16336 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 16336 R-BTA-2318623 https://reactome.org/PathwayBrowser/#/R-BTA-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Bos taurus 16336 R-BTA-2534346 https://reactome.org/PathwayBrowser/#/R-BTA-2534346 SPAM1 Binds Hyaluronic Acid IEA Bos taurus 16336 R-BTA-5693356 https://reactome.org/PathwayBrowser/#/R-BTA-5693356 CEMIP hydrolyses HA IEA Bos taurus 16336 R-CEL-2142859 https://reactome.org/PathwayBrowser/#/R-CEL-2142859 Growing HA is extruded from the cell by ABCC5 IEA Caenorhabditis elegans 16336 R-CEL-2160892 https://reactome.org/PathwayBrowser/#/R-CEL-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Caenorhabditis elegans 16336 R-CEL-2534346 https://reactome.org/PathwayBrowser/#/R-CEL-2534346 SPAM1 Binds Hyaluronic Acid IEA Caenorhabditis elegans 16336 R-CFA-1306876 https://reactome.org/PathwayBrowser/#/R-CFA-1306876 NLRP3 activation by small molecules IEA Canis familiaris 16336 R-CFA-2142859 https://reactome.org/PathwayBrowser/#/R-CFA-2142859 Growing HA is extruded from the cell by ABCC5 IEA Canis familiaris 16336 R-CFA-2160892 https://reactome.org/PathwayBrowser/#/R-CFA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Canis familiaris 16336 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 16336 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 16336 R-CFA-2318623 https://reactome.org/PathwayBrowser/#/R-CFA-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Canis familiaris 16336 R-CFA-2534346 https://reactome.org/PathwayBrowser/#/R-CFA-2534346 SPAM1 Binds Hyaluronic Acid IEA Canis familiaris 16336 R-CFA-5693356 https://reactome.org/PathwayBrowser/#/R-CFA-5693356 CEMIP hydrolyses HA IEA Canis familiaris 16336 R-DDI-5693356 https://reactome.org/PathwayBrowser/#/R-DDI-5693356 CEMIP hydrolyses HA IEA Dictyostelium discoideum 16336 R-DRE-1306876 https://reactome.org/PathwayBrowser/#/R-DRE-1306876 NLRP3 activation by small molecules IEA Danio rerio 16336 R-DRE-2142859 https://reactome.org/PathwayBrowser/#/R-DRE-2142859 Growing HA is extruded from the cell by ABCC5 IEA Danio rerio 16336 R-DRE-2534346 https://reactome.org/PathwayBrowser/#/R-DRE-2534346 SPAM1 Binds Hyaluronic Acid IEA Danio rerio 16336 R-GGA-1306876 https://reactome.org/PathwayBrowser/#/R-GGA-1306876 NLRP3 activation by small molecules IEA Gallus gallus 16336 R-GGA-2142859 https://reactome.org/PathwayBrowser/#/R-GGA-2142859 Growing HA is extruded from the cell by ABCC5 IEA Gallus gallus 16336 R-GGA-2160884 https://reactome.org/PathwayBrowser/#/R-GGA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Gallus gallus 16336 R-GGA-2160892 https://reactome.org/PathwayBrowser/#/R-GGA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Gallus gallus 16336 R-GGA-2160915 https://reactome.org/PathwayBrowser/#/R-GGA-2160915 Receptor-mediated uptake of HA IEA Gallus gallus 16336 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 16336 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 16336 R-GGA-2318623 https://reactome.org/PathwayBrowser/#/R-GGA-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Gallus gallus 16336 R-GGA-2534346 https://reactome.org/PathwayBrowser/#/R-GGA-2534346 SPAM1 Binds Hyaluronic Acid IEA Gallus gallus 16336 R-GGA-5693356 https://reactome.org/PathwayBrowser/#/R-GGA-5693356 CEMIP hydrolyses HA IEA Gallus gallus 16336 R-HSA-1296421 https://reactome.org/PathwayBrowser/#/R-HSA-1296421 NLRP3 oligomerizes via NACHT domains TAS Homo sapiens 16336 R-HSA-1306876 https://reactome.org/PathwayBrowser/#/R-HSA-1306876 NLRP3 activation by small molecules TAS Homo sapiens 16336 R-HSA-2142859 https://reactome.org/PathwayBrowser/#/R-HSA-2142859 Growing HA is extruded from the cell by ABCC5 TAS Homo sapiens 16336 R-HSA-2160884 https://reactome.org/PathwayBrowser/#/R-HSA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ TAS Homo sapiens 16336 R-HSA-2160892 https://reactome.org/PathwayBrowser/#/R-HSA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments TAS Homo sapiens 16336 R-HSA-2160915 https://reactome.org/PathwayBrowser/#/R-HSA-2160915 Receptor-mediated uptake of HA TAS Homo sapiens 16336 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 16336 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 16336 R-HSA-2318623 https://reactome.org/PathwayBrowser/#/R-HSA-2318623 Aggrecan binds Hyaluronan and HAPLN1 TAS Homo sapiens 16336 R-HSA-2534346 https://reactome.org/PathwayBrowser/#/R-HSA-2534346 SPAM1 Binds Hyaluronic Acid TAS Homo sapiens 16336 R-HSA-5693356 https://reactome.org/PathwayBrowser/#/R-HSA-5693356 CEMIP hydrolyses HA TAS Homo sapiens 16336 R-HSA-844610 https://reactome.org/PathwayBrowser/#/R-HSA-844610 NLRP3 recruits PYCARD (ASC) via a PYD-PYD interaction TAS Homo sapiens 16336 R-HSA-844612 https://reactome.org/PathwayBrowser/#/R-HSA-844612 PYCARD recruits procaspase-1 via CARD TAS Homo sapiens 16336 R-MMU-1306876 https://reactome.org/PathwayBrowser/#/R-MMU-1306876 NLRP3 activation by small molecules IEA Mus musculus 16336 R-MMU-2142859 https://reactome.org/PathwayBrowser/#/R-MMU-2142859 Growing HA is extruded from the cell by ABCC5 IEA Mus musculus 16336 R-MMU-2160884 https://reactome.org/PathwayBrowser/#/R-MMU-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Mus musculus 16336 R-MMU-2160892 https://reactome.org/PathwayBrowser/#/R-MMU-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Mus musculus 16336 R-MMU-2160915 https://reactome.org/PathwayBrowser/#/R-MMU-2160915 Receptor-mediated uptake of HA IEA Mus musculus 16336 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 16336 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 16336 R-MMU-2318623 https://reactome.org/PathwayBrowser/#/R-MMU-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Mus musculus 16336 R-MMU-2534346 https://reactome.org/PathwayBrowser/#/R-MMU-2534346 SPAM1 Binds Hyaluronic Acid IEA Mus musculus 16336 R-MMU-5693356 https://reactome.org/PathwayBrowser/#/R-MMU-5693356 CEMIP hydrolyses HA IEA Mus musculus 16336 R-RNO-1306876 https://reactome.org/PathwayBrowser/#/R-RNO-1306876 NLRP3 activation by small molecules IEA Rattus norvegicus 16336 R-RNO-2142859 https://reactome.org/PathwayBrowser/#/R-RNO-2142859 Growing HA is extruded from the cell by ABCC5 IEA Rattus norvegicus 16336 R-RNO-2160884 https://reactome.org/PathwayBrowser/#/R-RNO-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Rattus norvegicus 16336 R-RNO-2160892 https://reactome.org/PathwayBrowser/#/R-RNO-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Rattus norvegicus 16336 R-RNO-2160915 https://reactome.org/PathwayBrowser/#/R-RNO-2160915 Receptor-mediated uptake of HA IEA Rattus norvegicus 16336 R-RNO-2318623 https://reactome.org/PathwayBrowser/#/R-RNO-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Rattus norvegicus 16336 R-RNO-2534346 https://reactome.org/PathwayBrowser/#/R-RNO-2534346 SPAM1 Binds Hyaluronic Acid IEA Rattus norvegicus 16336 R-RNO-5693356 https://reactome.org/PathwayBrowser/#/R-RNO-5693356 CEMIP hydrolyses HA IEA Rattus norvegicus 16336 R-SSC-1306876 https://reactome.org/PathwayBrowser/#/R-SSC-1306876 NLRP3 activation by small molecules IEA Sus scrofa 16336 R-SSC-2142859 https://reactome.org/PathwayBrowser/#/R-SSC-2142859 Growing HA is extruded from the cell by ABCC5 IEA Sus scrofa 16336 R-SSC-2160884 https://reactome.org/PathwayBrowser/#/R-SSC-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Sus scrofa 16336 R-SSC-2160892 https://reactome.org/PathwayBrowser/#/R-SSC-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Sus scrofa 16336 R-SSC-2160915 https://reactome.org/PathwayBrowser/#/R-SSC-2160915 Receptor-mediated uptake of HA IEA Sus scrofa 16336 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 16336 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 16336 R-SSC-2318623 https://reactome.org/PathwayBrowser/#/R-SSC-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Sus scrofa 16336 R-SSC-2534346 https://reactome.org/PathwayBrowser/#/R-SSC-2534346 SPAM1 Binds Hyaluronic Acid IEA Sus scrofa 16336 R-SSC-5693356 https://reactome.org/PathwayBrowser/#/R-SSC-5693356 CEMIP hydrolyses HA IEA Sus scrofa 16336 R-XTR-1306876 https://reactome.org/PathwayBrowser/#/R-XTR-1306876 NLRP3 activation by small molecules IEA Xenopus tropicalis 16336 R-XTR-2142859 https://reactome.org/PathwayBrowser/#/R-XTR-2142859 Growing HA is extruded from the cell by ABCC5 IEA Xenopus tropicalis 16336 R-XTR-2160892 https://reactome.org/PathwayBrowser/#/R-XTR-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Xenopus tropicalis 16336 R-XTR-2534346 https://reactome.org/PathwayBrowser/#/R-XTR-2534346 SPAM1 Binds Hyaluronic Acid IEA Xenopus tropicalis 16344 R-BTA-71275 https://reactome.org/PathwayBrowser/#/R-BTA-71275 arginine + glycine => ornithine + guanidoacetate IEA Bos taurus 16344 R-BTA-71286 https://reactome.org/PathwayBrowser/#/R-BTA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Bos taurus 16344 R-CFA-71275 https://reactome.org/PathwayBrowser/#/R-CFA-71275 arginine + glycine => ornithine + guanidoacetate IEA Canis familiaris 16344 R-CFA-71286 https://reactome.org/PathwayBrowser/#/R-CFA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Canis familiaris 16344 R-DRE-71275 https://reactome.org/PathwayBrowser/#/R-DRE-71275 arginine + glycine => ornithine + guanidoacetate IEA Danio rerio 16344 R-DRE-71286 https://reactome.org/PathwayBrowser/#/R-DRE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Danio rerio 16344 R-GGA-71275 https://reactome.org/PathwayBrowser/#/R-GGA-71275 arginine + glycine => ornithine + guanidoacetate IEA Gallus gallus 16344 R-GGA-71286 https://reactome.org/PathwayBrowser/#/R-GGA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Gallus gallus 16344 R-HSA-71275 https://reactome.org/PathwayBrowser/#/R-HSA-71275 arginine + glycine => ornithine + guanidoacetate TAS Homo sapiens 16344 R-HSA-71286 https://reactome.org/PathwayBrowser/#/R-HSA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine TAS Homo sapiens 16344 R-MMU-71275 https://reactome.org/PathwayBrowser/#/R-MMU-71275 arginine + glycine => ornithine + guanidoacetate IEA Mus musculus 16344 R-MMU-71286 https://reactome.org/PathwayBrowser/#/R-MMU-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Mus musculus 16344 R-RNO-71275 https://reactome.org/PathwayBrowser/#/R-RNO-71275 arginine + glycine => ornithine + guanidoacetate IEA Rattus norvegicus 16344 R-RNO-71286 https://reactome.org/PathwayBrowser/#/R-RNO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Rattus norvegicus 16344 R-SCE-71286 https://reactome.org/PathwayBrowser/#/R-SCE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Saccharomyces cerevisiae 16344 R-SPO-71286 https://reactome.org/PathwayBrowser/#/R-SPO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Schizosaccharomyces pombe 16344 R-SSC-71275 https://reactome.org/PathwayBrowser/#/R-SSC-71275 arginine + glycine => ornithine + guanidoacetate IEA Sus scrofa 16344 R-SSC-71286 https://reactome.org/PathwayBrowser/#/R-SSC-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Sus scrofa 16344 R-XTR-71275 https://reactome.org/PathwayBrowser/#/R-XTR-71275 arginine + glycine => ornithine + guanidoacetate IEA Xenopus tropicalis 16344 R-XTR-71286 https://reactome.org/PathwayBrowser/#/R-XTR-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Xenopus tropicalis 16356 R-BTA-2514865 https://reactome.org/PathwayBrowser/#/R-BTA-2514865 cGMP dissociates from CNG channels IEA Bos taurus 16356 R-BTA-2514867 https://reactome.org/PathwayBrowser/#/R-BTA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Bos taurus 16356 R-BTA-4086392 https://reactome.org/PathwayBrowser/#/R-BTA-4086392 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 16356 R-BTA-418456 https://reactome.org/PathwayBrowser/#/R-BTA-418456 cGMP is degraded by PDEs IEA Bos taurus 16356 R-BTA-445813 https://reactome.org/PathwayBrowser/#/R-BTA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Bos taurus 16356 R-BTA-74031 https://reactome.org/PathwayBrowser/#/R-BTA-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Bos taurus 16356 R-BTA-74059 https://reactome.org/PathwayBrowser/#/R-BTA-74059 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 16356 R-BTA-74885 https://reactome.org/PathwayBrowser/#/R-BTA-74885 GUCYs converts GTP to cGMP IEA Bos taurus 16356 R-BTA-9653503 https://reactome.org/PathwayBrowser/#/R-BTA-9653503 KRAS4B is phosphorylated on serine 181 IEA Bos taurus 16356 R-CEL-2514865 https://reactome.org/PathwayBrowser/#/R-CEL-2514865 cGMP dissociates from CNG channels IEA Caenorhabditis elegans 16356 R-CEL-2514867 https://reactome.org/PathwayBrowser/#/R-CEL-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Caenorhabditis elegans 16356 R-CEL-418456 https://reactome.org/PathwayBrowser/#/R-CEL-418456 cGMP is degraded by PDEs IEA Caenorhabditis elegans 16356 R-CEL-74031 https://reactome.org/PathwayBrowser/#/R-CEL-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Caenorhabditis elegans 16356 R-CEL-74885 https://reactome.org/PathwayBrowser/#/R-CEL-74885 GUCYs converts GTP to cGMP IEA Caenorhabditis elegans 16356 R-CFA-2514865 https://reactome.org/PathwayBrowser/#/R-CFA-2514865 cGMP dissociates from CNG channels IEA Canis familiaris 16356 R-CFA-2514867 https://reactome.org/PathwayBrowser/#/R-CFA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Canis familiaris 16356 R-CFA-4086392 https://reactome.org/PathwayBrowser/#/R-CFA-4086392 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 16356 R-CFA-418456 https://reactome.org/PathwayBrowser/#/R-CFA-418456 cGMP is degraded by PDEs IEA Canis familiaris 16356 R-CFA-445813 https://reactome.org/PathwayBrowser/#/R-CFA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Canis familiaris 16356 R-CFA-74031 https://reactome.org/PathwayBrowser/#/R-CFA-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Canis familiaris 16356 R-CFA-74059 https://reactome.org/PathwayBrowser/#/R-CFA-74059 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 16356 R-CFA-74885 https://reactome.org/PathwayBrowser/#/R-CFA-74885 GUCYs converts GTP to cGMP IEA Canis familiaris 16356 R-CFA-9653503 https://reactome.org/PathwayBrowser/#/R-CFA-9653503 KRAS4B is phosphorylated on serine 181 IEA Canis familiaris 16356 R-DDI-418456 https://reactome.org/PathwayBrowser/#/R-DDI-418456 cGMP is degraded by PDEs IEA Dictyostelium discoideum 16356 R-DDI-74885 https://reactome.org/PathwayBrowser/#/R-DDI-74885 GUCYs converts GTP to cGMP IEA Dictyostelium discoideum 16356 R-DME-2514865 https://reactome.org/PathwayBrowser/#/R-DME-2514865 cGMP dissociates from CNG channels IEA Drosophila melanogaster 16356 R-DME-2514867 https://reactome.org/PathwayBrowser/#/R-DME-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Drosophila melanogaster 16356 R-DME-418456 https://reactome.org/PathwayBrowser/#/R-DME-418456 cGMP is degraded by PDEs IEA Drosophila melanogaster 16356 R-DME-74031 https://reactome.org/PathwayBrowser/#/R-DME-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Drosophila melanogaster 16356 R-DME-74885 https://reactome.org/PathwayBrowser/#/R-DME-74885 GUCYs converts GTP to cGMP IEA Drosophila melanogaster 16356 R-DME-9653503 https://reactome.org/PathwayBrowser/#/R-DME-9653503 KRAS4B is phosphorylated on serine 181 IEA Drosophila melanogaster 16356 R-GGA-2514865 https://reactome.org/PathwayBrowser/#/R-GGA-2514865 cGMP dissociates from CNG channels IEA Gallus gallus 16356 R-GGA-2514867 https://reactome.org/PathwayBrowser/#/R-GGA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Gallus gallus 16356 R-GGA-4086392 https://reactome.org/PathwayBrowser/#/R-GGA-4086392 PDE6 hydrolyses cGMP to GMP IEA Gallus gallus 16356 R-GGA-418456 https://reactome.org/PathwayBrowser/#/R-GGA-418456 cGMP is degraded by PDEs IEA Gallus gallus 16356 R-GGA-445813 https://reactome.org/PathwayBrowser/#/R-GGA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Gallus gallus 16356 R-GGA-74031 https://reactome.org/PathwayBrowser/#/R-GGA-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Gallus gallus 16356 R-GGA-9653503 https://reactome.org/PathwayBrowser/#/R-GGA-9653503 KRAS4B is phosphorylated on serine 181 IEA Gallus gallus 16356 R-HAM-427308 https://reactome.org/PathwayBrowser/#/R-HAM-427308 cGMP stimulates Protein Kinase G TAS Homarus americanus 16356 R-HSA-2514865 https://reactome.org/PathwayBrowser/#/R-HSA-2514865 cGMP dissociates from CNG channels TAS Homo sapiens 16356 R-HSA-2514867 https://reactome.org/PathwayBrowser/#/R-HSA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment TAS Homo sapiens 16356 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 16356 R-HSA-4086392 https://reactome.org/PathwayBrowser/#/R-HSA-4086392 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 16356 R-HSA-418451 https://reactome.org/PathwayBrowser/#/R-HSA-418451 cGMP stimulates Protein Kinase G IEA Homo sapiens 16356 R-HSA-418456 https://reactome.org/PathwayBrowser/#/R-HSA-418456 cGMP is degraded by PDEs TAS Homo sapiens 16356 R-HSA-445813 https://reactome.org/PathwayBrowser/#/R-HSA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains TAS Homo sapiens 16356 R-HSA-4551453 https://reactome.org/PathwayBrowser/#/R-HSA-4551453 PRKG is activated by binding to high levels of cGMP in the absence of WNT signaling IEA Homo sapiens 16356 R-HSA-74031 https://reactome.org/PathwayBrowser/#/R-HSA-74031 cGMP binds CNG channel to form cGMP:CNG channel TAS Homo sapiens 16356 R-HSA-74059 https://reactome.org/PathwayBrowser/#/R-HSA-74059 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 16356 R-HSA-74885 https://reactome.org/PathwayBrowser/#/R-HSA-74885 GUCYs converts GTP to cGMP TAS Homo sapiens 16356 R-HSA-9653503 https://reactome.org/PathwayBrowser/#/R-HSA-9653503 KRAS4B is phosphorylated on serine 181 TAS Homo sapiens 16356 R-MMU-2514865 https://reactome.org/PathwayBrowser/#/R-MMU-2514865 cGMP dissociates from CNG channels IEA Mus musculus 16356 R-MMU-2514867 https://reactome.org/PathwayBrowser/#/R-MMU-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Mus musculus 16356 R-MMU-4086392 https://reactome.org/PathwayBrowser/#/R-MMU-4086392 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 16356 R-MMU-418456 https://reactome.org/PathwayBrowser/#/R-MMU-418456 cGMP is degraded by PDEs IEA Mus musculus 16356 R-MMU-445813 https://reactome.org/PathwayBrowser/#/R-MMU-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Mus musculus 16356 R-MMU-4551446 https://reactome.org/PathwayBrowser/#/R-MMU-4551446 Prkg is activated upon cGMP binding TAS Mus musculus 16356 R-MMU-74031 https://reactome.org/PathwayBrowser/#/R-MMU-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Mus musculus 16356 R-MMU-74059 https://reactome.org/PathwayBrowser/#/R-MMU-74059 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 16356 R-MMU-74885 https://reactome.org/PathwayBrowser/#/R-MMU-74885 GUCYs converts GTP to cGMP IEA Mus musculus 16356 R-MMU-9653503 https://reactome.org/PathwayBrowser/#/R-MMU-9653503 KRAS4B is phosphorylated on serine 181 IEA Mus musculus 16356 R-PFA-418456 https://reactome.org/PathwayBrowser/#/R-PFA-418456 cGMP is degraded by PDEs IEA Plasmodium falciparum 16356 R-RNO-2514865 https://reactome.org/PathwayBrowser/#/R-RNO-2514865 cGMP dissociates from CNG channels IEA Rattus norvegicus 16356 R-RNO-2514867 https://reactome.org/PathwayBrowser/#/R-RNO-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Rattus norvegicus 16356 R-RNO-4086392 https://reactome.org/PathwayBrowser/#/R-RNO-4086392 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 16356 R-RNO-418456 https://reactome.org/PathwayBrowser/#/R-RNO-418456 cGMP is degraded by PDEs IEA Rattus norvegicus 16356 R-RNO-427288 https://reactome.org/PathwayBrowser/#/R-RNO-427288 Soluble guanylate cyclase converts GTP to cGMP TAS Rattus norvegicus 16356 R-RNO-445813 https://reactome.org/PathwayBrowser/#/R-RNO-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Rattus norvegicus 16356 R-RNO-74031 https://reactome.org/PathwayBrowser/#/R-RNO-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Rattus norvegicus 16356 R-RNO-74059 https://reactome.org/PathwayBrowser/#/R-RNO-74059 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 16356 R-RNO-74885 https://reactome.org/PathwayBrowser/#/R-RNO-74885 GUCYs converts GTP to cGMP IEA Rattus norvegicus 16356 R-RNO-9653503 https://reactome.org/PathwayBrowser/#/R-RNO-9653503 KRAS4B is phosphorylated on serine 181 IEA Rattus norvegicus 16356 R-SCE-418456 https://reactome.org/PathwayBrowser/#/R-SCE-418456 cGMP is degraded by PDEs IEA Saccharomyces cerevisiae 16356 R-SSC-2514865 https://reactome.org/PathwayBrowser/#/R-SSC-2514865 cGMP dissociates from CNG channels IEA Sus scrofa 16356 R-SSC-2514867 https://reactome.org/PathwayBrowser/#/R-SSC-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Sus scrofa 16356 R-SSC-4086392 https://reactome.org/PathwayBrowser/#/R-SSC-4086392 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 16356 R-SSC-418456 https://reactome.org/PathwayBrowser/#/R-SSC-418456 cGMP is degraded by PDEs IEA Sus scrofa 16356 R-SSC-445813 https://reactome.org/PathwayBrowser/#/R-SSC-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Sus scrofa 16356 R-SSC-74031 https://reactome.org/PathwayBrowser/#/R-SSC-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Sus scrofa 16356 R-SSC-74059 https://reactome.org/PathwayBrowser/#/R-SSC-74059 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 16356 R-SSC-74885 https://reactome.org/PathwayBrowser/#/R-SSC-74885 GUCYs converts GTP to cGMP IEA Sus scrofa 16356 R-SSC-9653503 https://reactome.org/PathwayBrowser/#/R-SSC-9653503 KRAS4B is phosphorylated on serine 181 IEA Sus scrofa 16356 R-XTR-4086392 https://reactome.org/PathwayBrowser/#/R-XTR-4086392 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 16356 R-XTR-418456 https://reactome.org/PathwayBrowser/#/R-XTR-418456 cGMP is degraded by PDEs IEA Xenopus tropicalis 16356 R-XTR-74059 https://reactome.org/PathwayBrowser/#/R-XTR-74059 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 16356 R-XTR-74885 https://reactome.org/PathwayBrowser/#/R-XTR-74885 GUCYs converts GTP to cGMP IEA Xenopus tropicalis 16382 R-BTA-209772 https://reactome.org/PathwayBrowser/#/R-BTA-209772 Thyroxine is deiodinated to triiodothyronine IEA Bos taurus 16382 R-BTA-209910 https://reactome.org/PathwayBrowser/#/R-BTA-209910 Iodide is taken up by thyroid epithelial cells IEA Bos taurus 16382 R-BTA-209921 https://reactome.org/PathwayBrowser/#/R-BTA-209921 Monoiodinated tyrosine can be deiodinated IEA Bos taurus 16382 R-BTA-209960 https://reactome.org/PathwayBrowser/#/R-BTA-209960 Diiodinated tyrosine can be deiodinated IEA Bos taurus 16382 R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 16382 R-BTA-350869 https://reactome.org/PathwayBrowser/#/R-BTA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Bos taurus 16382 R-BTA-350901 https://reactome.org/PathwayBrowser/#/R-BTA-350901 Iodide is organified IEA Bos taurus 16382 R-BTA-429591 https://reactome.org/PathwayBrowser/#/R-BTA-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Bos taurus 16382 R-BTA-429767 https://reactome.org/PathwayBrowser/#/R-BTA-429767 Passive I- efflux mediated by SMCT1 IEA Bos taurus 16382 R-BTA-5627802 https://reactome.org/PathwayBrowser/#/R-BTA-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Bos taurus 16382 R-BTA-8941543 https://reactome.org/PathwayBrowser/#/R-BTA-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Bos taurus 16382 R-CEL-209910 https://reactome.org/PathwayBrowser/#/R-CEL-209910 Iodide is taken up by thyroid epithelial cells IEA Caenorhabditis elegans 16382 R-CEL-209921 https://reactome.org/PathwayBrowser/#/R-CEL-209921 Monoiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 16382 R-CEL-209960 https://reactome.org/PathwayBrowser/#/R-CEL-209960 Diiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 16382 R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 16382 R-CEL-350901 https://reactome.org/PathwayBrowser/#/R-CEL-350901 Iodide is organified IEA Caenorhabditis elegans 16382 R-CEL-429591 https://reactome.org/PathwayBrowser/#/R-CEL-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Caenorhabditis elegans 16382 R-CEL-429767 https://reactome.org/PathwayBrowser/#/R-CEL-429767 Passive I- efflux mediated by SMCT1 IEA Caenorhabditis elegans 16382 R-CEL-5627802 https://reactome.org/PathwayBrowser/#/R-CEL-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Caenorhabditis elegans 16382 R-CEL-8941543 https://reactome.org/PathwayBrowser/#/R-CEL-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Caenorhabditis elegans 16382 R-CFA-209772 https://reactome.org/PathwayBrowser/#/R-CFA-209772 Thyroxine is deiodinated to triiodothyronine IEA Canis familiaris 16382 R-CFA-209910 https://reactome.org/PathwayBrowser/#/R-CFA-209910 Iodide is taken up by thyroid epithelial cells IEA Canis familiaris 16382 R-CFA-209921 https://reactome.org/PathwayBrowser/#/R-CFA-209921 Monoiodinated tyrosine can be deiodinated IEA Canis familiaris 16382 R-CFA-209960 https://reactome.org/PathwayBrowser/#/R-CFA-209960 Diiodinated tyrosine can be deiodinated IEA Canis familiaris 16382 R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 16382 R-CFA-350901 https://reactome.org/PathwayBrowser/#/R-CFA-350901 Iodide is organified IEA Canis familiaris 16382 R-CFA-429591 https://reactome.org/PathwayBrowser/#/R-CFA-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Canis familiaris 16382 R-CFA-429767 https://reactome.org/PathwayBrowser/#/R-CFA-429767 Passive I- efflux mediated by SMCT1 IEA Canis familiaris 16382 R-CFA-5627802 https://reactome.org/PathwayBrowser/#/R-CFA-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Canis familiaris 16382 R-CFA-8941543 https://reactome.org/PathwayBrowser/#/R-CFA-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Canis familiaris 16382 R-DDI-209772 https://reactome.org/PathwayBrowser/#/R-DDI-209772 Thyroxine is deiodinated to triiodothyronine IEA Dictyostelium discoideum 16382 R-DDI-209973 https://reactome.org/PathwayBrowser/#/R-DDI-209973 Tyrosine is diiodinated IEA Dictyostelium discoideum 16382 R-DDI-350869 https://reactome.org/PathwayBrowser/#/R-DDI-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Dictyostelium discoideum 16382 R-DDI-350901 https://reactome.org/PathwayBrowser/#/R-DDI-350901 Iodide is organified IEA Dictyostelium discoideum 16382 R-DDI-5627802 https://reactome.org/PathwayBrowser/#/R-DDI-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Dictyostelium discoideum 16382 R-DME-209910 https://reactome.org/PathwayBrowser/#/R-DME-209910 Iodide is taken up by thyroid epithelial cells IEA Drosophila melanogaster 16382 R-DME-209921 https://reactome.org/PathwayBrowser/#/R-DME-209921 Monoiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 16382 R-DME-209960 https://reactome.org/PathwayBrowser/#/R-DME-209960 Diiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 16382 R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 16382 R-DME-350901 https://reactome.org/PathwayBrowser/#/R-DME-350901 Iodide is organified IEA Drosophila melanogaster 16382 R-DME-429591 https://reactome.org/PathwayBrowser/#/R-DME-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Drosophila melanogaster 16382 R-DME-429767 https://reactome.org/PathwayBrowser/#/R-DME-429767 Passive I- efflux mediated by SMCT1 IEA Drosophila melanogaster 16382 R-DME-5627802 https://reactome.org/PathwayBrowser/#/R-DME-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Drosophila melanogaster 16382 R-DME-8941543 https://reactome.org/PathwayBrowser/#/R-DME-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Drosophila melanogaster 16382 R-DRE-209910 https://reactome.org/PathwayBrowser/#/R-DRE-209910 Iodide is taken up by thyroid epithelial cells IEA Danio rerio 16382 R-DRE-209921 https://reactome.org/PathwayBrowser/#/R-DRE-209921 Monoiodinated tyrosine can be deiodinated IEA Danio rerio 16382 R-DRE-209960 https://reactome.org/PathwayBrowser/#/R-DRE-209960 Diiodinated tyrosine can be deiodinated IEA Danio rerio 16382 R-DRE-429591 https://reactome.org/PathwayBrowser/#/R-DRE-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Danio rerio 16382 R-DRE-429767 https://reactome.org/PathwayBrowser/#/R-DRE-429767 Passive I- efflux mediated by SMCT1 IEA Danio rerio 16382 R-DRE-8941543 https://reactome.org/PathwayBrowser/#/R-DRE-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Danio rerio 16382 R-GGA-209772 https://reactome.org/PathwayBrowser/#/R-GGA-209772 Thyroxine is deiodinated to triiodothyronine IEA Gallus gallus 16382 R-GGA-209910 https://reactome.org/PathwayBrowser/#/R-GGA-209910 Iodide is taken up by thyroid epithelial cells IEA Gallus gallus 16382 R-GGA-209921 https://reactome.org/PathwayBrowser/#/R-GGA-209921 Monoiodinated tyrosine can be deiodinated IEA Gallus gallus 16382 R-GGA-209960 https://reactome.org/PathwayBrowser/#/R-GGA-209960 Diiodinated tyrosine can be deiodinated IEA Gallus gallus 16382 R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 16382 R-GGA-350901 https://reactome.org/PathwayBrowser/#/R-GGA-350901 Iodide is organified IEA Gallus gallus 16382 R-GGA-429591 https://reactome.org/PathwayBrowser/#/R-GGA-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Gallus gallus 16382 R-GGA-429767 https://reactome.org/PathwayBrowser/#/R-GGA-429767 Passive I- efflux mediated by SMCT1 IEA Gallus gallus 16382 R-GGA-5627802 https://reactome.org/PathwayBrowser/#/R-GGA-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Gallus gallus 16382 R-GGA-8941543 https://reactome.org/PathwayBrowser/#/R-GGA-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Gallus gallus 16382 R-HSA-209772 https://reactome.org/PathwayBrowser/#/R-HSA-209772 Thyroxine is deiodinated to triiodothyronine TAS Homo sapiens 16382 R-HSA-209910 https://reactome.org/PathwayBrowser/#/R-HSA-209910 Iodide is taken up by thyroid epithelial cells TAS Homo sapiens 16382 R-HSA-209921 https://reactome.org/PathwayBrowser/#/R-HSA-209921 Monoiodinated tyrosine can be deiodinated TAS Homo sapiens 16382 R-HSA-209960 https://reactome.org/PathwayBrowser/#/R-HSA-209960 Diiodinated tyrosine can be deiodinated TAS Homo sapiens 16382 R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 16382 R-HSA-350869 https://reactome.org/PathwayBrowser/#/R-HSA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) TAS Homo sapiens 16382 R-HSA-350901 https://reactome.org/PathwayBrowser/#/R-HSA-350901 Iodide is organified TAS Homo sapiens 16382 R-HSA-429591 https://reactome.org/PathwayBrowser/#/R-HSA-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol TAS Homo sapiens 16382 R-HSA-429767 https://reactome.org/PathwayBrowser/#/R-HSA-429767 Passive I- efflux mediated by SMCT1 TAS Homo sapiens 16382 R-HSA-432034 https://reactome.org/PathwayBrowser/#/R-HSA-432034 Aquaporin-6 passively transports anions into vesicles IEA Homo sapiens 16382 R-HSA-432036 https://reactome.org/PathwayBrowser/#/R-HSA-432036 Aquaporin-6 passively transports anions out of vesicles IEA Homo sapiens 16382 R-HSA-5627802 https://reactome.org/PathwayBrowser/#/R-HSA-5627802 SLC26A4 transports I- from cytosol to extracellular region TAS Homo sapiens 16382 R-HSA-5627870 https://reactome.org/PathwayBrowser/#/R-HSA-5627870 SLC26A4 does not transport I- from cytosol to extracellular region TAS Homo sapiens 16382 R-HSA-5658195 https://reactome.org/PathwayBrowser/#/R-HSA-5658195 Defective SLC5A5 does not cotransport Na+ with I- from extracellular region to cytosol TAS Homo sapiens 16382 R-HSA-8941543 https://reactome.org/PathwayBrowser/#/R-HSA-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region TAS Homo sapiens 16382 R-MMU-209772 https://reactome.org/PathwayBrowser/#/R-MMU-209772 Thyroxine is deiodinated to triiodothyronine IEA Mus musculus 16382 R-MMU-209910 https://reactome.org/PathwayBrowser/#/R-MMU-209910 Iodide is taken up by thyroid epithelial cells IEA Mus musculus 16382 R-MMU-209921 https://reactome.org/PathwayBrowser/#/R-MMU-209921 Monoiodinated tyrosine can be deiodinated IEA Mus musculus 16382 R-MMU-209960 https://reactome.org/PathwayBrowser/#/R-MMU-209960 Diiodinated tyrosine can be deiodinated IEA Mus musculus 16382 R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 16382 R-MMU-350869 https://reactome.org/PathwayBrowser/#/R-MMU-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Mus musculus 16382 R-MMU-350901 https://reactome.org/PathwayBrowser/#/R-MMU-350901 Iodide is organified IEA Mus musculus 16382 R-MMU-429591 https://reactome.org/PathwayBrowser/#/R-MMU-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Mus musculus 16382 R-MMU-429767 https://reactome.org/PathwayBrowser/#/R-MMU-429767 Passive I- efflux mediated by SMCT1 IEA Mus musculus 16382 R-MMU-5627802 https://reactome.org/PathwayBrowser/#/R-MMU-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Mus musculus 16382 R-MMU-8941543 https://reactome.org/PathwayBrowser/#/R-MMU-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Mus musculus 16382 R-RNO-209772 https://reactome.org/PathwayBrowser/#/R-RNO-209772 Thyroxine is deiodinated to triiodothyronine IEA Rattus norvegicus 16382 R-RNO-209910 https://reactome.org/PathwayBrowser/#/R-RNO-209910 Iodide is taken up by thyroid epithelial cells IEA Rattus norvegicus 16382 R-RNO-209921 https://reactome.org/PathwayBrowser/#/R-RNO-209921 Monoiodinated tyrosine can be deiodinated IEA Rattus norvegicus 16382 R-RNO-209960 https://reactome.org/PathwayBrowser/#/R-RNO-209960 Diiodinated tyrosine can be deiodinated IEA Rattus norvegicus 16382 R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 16382 R-RNO-350869 https://reactome.org/PathwayBrowser/#/R-RNO-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Rattus norvegicus 16382 R-RNO-350901 https://reactome.org/PathwayBrowser/#/R-RNO-350901 Iodide is organified IEA Rattus norvegicus 16382 R-RNO-429591 https://reactome.org/PathwayBrowser/#/R-RNO-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Rattus norvegicus 16382 R-RNO-429767 https://reactome.org/PathwayBrowser/#/R-RNO-429767 Passive I- efflux mediated by SMCT1 IEA Rattus norvegicus 16382 R-RNO-5627802 https://reactome.org/PathwayBrowser/#/R-RNO-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Rattus norvegicus 16382 R-RNO-879862 https://reactome.org/PathwayBrowser/#/R-RNO-879862 Passive Transport of Anions into Vesicles by Aquaporin-6 (rat) TAS Rattus norvegicus 16382 R-RNO-879863 https://reactome.org/PathwayBrowser/#/R-RNO-879863 Passive Transport of Anions out of Vesicles by Aquaporin-6 (rat) TAS Rattus norvegicus 16382 R-RNO-8941543 https://reactome.org/PathwayBrowser/#/R-RNO-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Rattus norvegicus 16382 R-SCE-5627802 https://reactome.org/PathwayBrowser/#/R-SCE-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Saccharomyces cerevisiae 16382 R-SPO-5627802 https://reactome.org/PathwayBrowser/#/R-SPO-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Schizosaccharomyces pombe 16382 R-SSC-209772 https://reactome.org/PathwayBrowser/#/R-SSC-209772 Thyroxine is deiodinated to triiodothyronine IEA Sus scrofa 16382 R-SSC-209910 https://reactome.org/PathwayBrowser/#/R-SSC-209910 Iodide is taken up by thyroid epithelial cells IEA Sus scrofa 16382 R-SSC-209921 https://reactome.org/PathwayBrowser/#/R-SSC-209921 Monoiodinated tyrosine can be deiodinated IEA Sus scrofa 16382 R-SSC-209960 https://reactome.org/PathwayBrowser/#/R-SSC-209960 Diiodinated tyrosine can be deiodinated IEA Sus scrofa 16382 R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 16382 R-SSC-350869 https://reactome.org/PathwayBrowser/#/R-SSC-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Sus scrofa 16382 R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa 16382 R-SSC-429591 https://reactome.org/PathwayBrowser/#/R-SSC-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Sus scrofa 16382 R-SSC-429767 https://reactome.org/PathwayBrowser/#/R-SSC-429767 Passive I- efflux mediated by SMCT1 IEA Sus scrofa 16382 R-SSC-5627802 https://reactome.org/PathwayBrowser/#/R-SSC-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Sus scrofa 16382 R-SSC-8941543 https://reactome.org/PathwayBrowser/#/R-SSC-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Sus scrofa 16382 R-XTR-209910 https://reactome.org/PathwayBrowser/#/R-XTR-209910 Iodide is taken up by thyroid epithelial cells IEA Xenopus tropicalis 16382 R-XTR-209921 https://reactome.org/PathwayBrowser/#/R-XTR-209921 Monoiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 16382 R-XTR-209960 https://reactome.org/PathwayBrowser/#/R-XTR-209960 Diiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 16382 R-XTR-429591 https://reactome.org/PathwayBrowser/#/R-XTR-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Xenopus tropicalis 16382 R-XTR-429767 https://reactome.org/PathwayBrowser/#/R-XTR-429767 Passive I- efflux mediated by SMCT1 IEA Xenopus tropicalis 16382 R-XTR-5627802 https://reactome.org/PathwayBrowser/#/R-XTR-5627802 SLC26A4 transports I- from cytosol to extracellular region IEA Xenopus tropicalis 16395 R-BTA-174963 https://reactome.org/PathwayBrowser/#/R-BTA-174963 NAT1 acetylation IEA Bos taurus 16395 R-BTA-174967 https://reactome.org/PathwayBrowser/#/R-BTA-174967 NAT2 acetylation IEA Bos taurus 16395 R-DRE-174963 https://reactome.org/PathwayBrowser/#/R-DRE-174963 NAT1 acetylation IEA Danio rerio 16395 R-DRE-174967 https://reactome.org/PathwayBrowser/#/R-DRE-174967 NAT2 acetylation IEA Danio rerio 16395 R-GGA-174963 https://reactome.org/PathwayBrowser/#/R-GGA-174963 NAT1 acetylation IEA Gallus gallus 16395 R-GGA-174967 https://reactome.org/PathwayBrowser/#/R-GGA-174967 NAT2 acetylation IEA Gallus gallus 16395 R-HSA-174963 https://reactome.org/PathwayBrowser/#/R-HSA-174963 NAT1 acetylation TAS Homo sapiens 16395 R-HSA-174967 https://reactome.org/PathwayBrowser/#/R-HSA-174967 NAT2 acetylation TAS Homo sapiens 16395 R-MMU-174963 https://reactome.org/PathwayBrowser/#/R-MMU-174963 NAT1 acetylation IEA Mus musculus 16395 R-MMU-174967 https://reactome.org/PathwayBrowser/#/R-MMU-174967 NAT2 acetylation IEA Mus musculus 16395 R-RNO-174963 https://reactome.org/PathwayBrowser/#/R-RNO-174963 NAT1 acetylation IEA Rattus norvegicus 16395 R-RNO-174967 https://reactome.org/PathwayBrowser/#/R-RNO-174967 NAT2 acetylation IEA Rattus norvegicus 16395 R-SSC-174963 https://reactome.org/PathwayBrowser/#/R-SSC-174963 NAT1 acetylation IEA Sus scrofa 16395 R-SSC-174967 https://reactome.org/PathwayBrowser/#/R-SSC-174967 NAT2 acetylation IEA Sus scrofa 16410 R-BTA-964958 https://reactome.org/PathwayBrowser/#/R-BTA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Bos taurus 16410 R-CEL-964958 https://reactome.org/PathwayBrowser/#/R-CEL-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Caenorhabditis elegans 16410 R-CFA-964958 https://reactome.org/PathwayBrowser/#/R-CFA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Canis familiaris 16410 R-DDI-964958 https://reactome.org/PathwayBrowser/#/R-DDI-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Dictyostelium discoideum 16410 R-DME-964958 https://reactome.org/PathwayBrowser/#/R-DME-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Drosophila melanogaster 16410 R-DRE-964958 https://reactome.org/PathwayBrowser/#/R-DRE-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Danio rerio 16410 R-GGA-964958 https://reactome.org/PathwayBrowser/#/R-GGA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Gallus gallus 16410 R-HSA-964958 https://reactome.org/PathwayBrowser/#/R-HSA-964958 2xPDXK:2xZn2+ phosphorylates PXA TAS Homo sapiens 16410 R-MMU-964958 https://reactome.org/PathwayBrowser/#/R-MMU-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Mus musculus 16410 R-PFA-964958 https://reactome.org/PathwayBrowser/#/R-PFA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Plasmodium falciparum 16410 R-RNO-964958 https://reactome.org/PathwayBrowser/#/R-RNO-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Rattus norvegicus 16410 R-SCE-964958 https://reactome.org/PathwayBrowser/#/R-SCE-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Saccharomyces cerevisiae 16410 R-SPO-964958 https://reactome.org/PathwayBrowser/#/R-SPO-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Schizosaccharomyces pombe 16410 R-SSC-964958 https://reactome.org/PathwayBrowser/#/R-SSC-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Sus scrofa 16410 R-XTR-964958 https://reactome.org/PathwayBrowser/#/R-XTR-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Xenopus tropicalis 16412 R-BTA-166015 https://reactome.org/PathwayBrowser/#/R-BTA-166015 Association of LBP with LPS IEA Bos taurus 16412 R-BTA-166038 https://reactome.org/PathwayBrowser/#/R-BTA-166038 GPI-bound CD14 binds LPS IEA Bos taurus 16412 R-BTA-166041 https://reactome.org/PathwayBrowser/#/R-BTA-166041 Transfer of LPS onto TLR4 IEA Bos taurus 16412 R-BTA-166168 https://reactome.org/PathwayBrowser/#/R-BTA-166168 TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) IEA Bos taurus 16412 R-BTA-166245 https://reactome.org/PathwayBrowser/#/R-BTA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Bos taurus 16412 R-BTA-166271 https://reactome.org/PathwayBrowser/#/R-BTA-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Bos taurus 16412 R-BTA-168915 https://reactome.org/PathwayBrowser/#/R-BTA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Bos taurus 16412 R-BTA-168921 https://reactome.org/PathwayBrowser/#/R-BTA-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 IEA Bos taurus 16412 R-BTA-169719 https://reactome.org/PathwayBrowser/#/R-BTA-169719 Secreted CD14 binds LPS IEA Bos taurus 16412 R-BTA-2197646 https://reactome.org/PathwayBrowser/#/R-BTA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Bos taurus 16412 R-BTA-2201293 https://reactome.org/PathwayBrowser/#/R-BTA-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Bos taurus 16412 R-BTA-2201338 https://reactome.org/PathwayBrowser/#/R-BTA-2201338 TRAF3 binds TICAM1:activated TLR4 complex IEA Bos taurus 16412 R-BTA-2203480 https://reactome.org/PathwayBrowser/#/R-BTA-2203480 COLEC11 binds ligands IEA Bos taurus 16412 R-BTA-2213017 https://reactome.org/PathwayBrowser/#/R-BTA-2213017 Auto-ubiquitination of TRAF3 IEA Bos taurus 16412 R-BTA-2512800 https://reactome.org/PathwayBrowser/#/R-BTA-2512800 SCARB1:ligand is endocytosed IEA Bos taurus 16412 R-BTA-2559439 https://reactome.org/PathwayBrowser/#/R-BTA-2559439 CD14:LPS binds CR3 IEA Bos taurus 16412 R-BTA-2559568 https://reactome.org/PathwayBrowser/#/R-BTA-2559568 SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 IEA Bos taurus 16412 R-BTA-2562541 https://reactome.org/PathwayBrowser/#/R-BTA-2562541 TLR4-induced ripoptosome assembly IEA Bos taurus 16412 R-BTA-2562564 https://reactome.org/PathwayBrowser/#/R-BTA-2562564 Caspase-8 processing within TLR4 complex IEA Bos taurus 16412 R-BTA-2569057 https://reactome.org/PathwayBrowser/#/R-BTA-2569057 RIP3 binds TRIF to mediate necroptosis IEA Bos taurus 16412 R-BTA-450358 https://reactome.org/PathwayBrowser/#/R-BTA-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Bos taurus 16412 R-BTA-5362486 https://reactome.org/PathwayBrowser/#/R-BTA-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 IEA Bos taurus 16412 R-BTA-5362500 https://reactome.org/PathwayBrowser/#/R-BTA-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Bos taurus 16412 R-BTA-6801762 https://reactome.org/PathwayBrowser/#/R-BTA-6801762 REG3A oligomerize to form a pore complex IEA Bos taurus 16412 R-BTA-6803063 https://reactome.org/PathwayBrowser/#/R-BTA-6803063 RNASEs bind bacterial LPS, PGN IEA Bos taurus 16412 R-BTA-6804100 https://reactome.org/PathwayBrowser/#/R-BTA-6804100 HMGB1 binds LPS IEA Bos taurus 16412 R-BTA-6807585 https://reactome.org/PathwayBrowser/#/R-BTA-6807585 BPI binds LPS on the bacterial surface IEA Bos taurus 16412 R-BTA-6810724 https://reactome.org/PathwayBrowser/#/R-BTA-6810724 PI3 binds the bacterial surface IEA Bos taurus 16412 R-BTA-936947 https://reactome.org/PathwayBrowser/#/R-BTA-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Bos taurus 16412 R-BTA-936951 https://reactome.org/PathwayBrowser/#/R-BTA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Bos taurus 16412 R-BTA-936952 https://reactome.org/PathwayBrowser/#/R-BTA-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex IEA Bos taurus 16412 R-BTA-936985 https://reactome.org/PathwayBrowser/#/R-BTA-936985 Activated TLR4:TICAM1 recruits TRAF6 IEA Bos taurus 16412 R-BTA-937029 https://reactome.org/PathwayBrowser/#/R-BTA-937029 IKBKG subunit of IKK complex binds polyubiquinated RIP1 IEA Bos taurus 16412 R-BTA-937075 https://reactome.org/PathwayBrowser/#/R-BTA-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Bos taurus 16412 R-BTA-9823904 https://reactome.org/PathwayBrowser/#/R-BTA-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Bos taurus 16412 R-BTA-9823906 https://reactome.org/PathwayBrowser/#/R-BTA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Bos taurus 16412 R-BTA-9823910 https://reactome.org/PathwayBrowser/#/R-BTA-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Bos taurus 16412 R-BTA-9823932 https://reactome.org/PathwayBrowser/#/R-BTA-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Bos taurus 16412 R-BTA-9823934 https://reactome.org/PathwayBrowser/#/R-BTA-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Bos taurus 16412 R-BTA-9823939 https://reactome.org/PathwayBrowser/#/R-BTA-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Bos taurus 16412 R-BTA-9824882 https://reactome.org/PathwayBrowser/#/R-BTA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Bos taurus 16412 R-CEL-166015 https://reactome.org/PathwayBrowser/#/R-CEL-166015 Association of LBP with LPS IEA Caenorhabditis elegans 16412 R-CEL-6801762 https://reactome.org/PathwayBrowser/#/R-CEL-6801762 REG3A oligomerize to form a pore complex IEA Caenorhabditis elegans 16412 R-CEL-6804100 https://reactome.org/PathwayBrowser/#/R-CEL-6804100 HMGB1 binds LPS IEA Caenorhabditis elegans 16412 R-CEL-6807585 https://reactome.org/PathwayBrowser/#/R-CEL-6807585 BPI binds LPS on the bacterial surface IEA Caenorhabditis elegans 16412 R-CFA-166015 https://reactome.org/PathwayBrowser/#/R-CFA-166015 Association of LBP with LPS IEA Canis familiaris 16412 R-CFA-166038 https://reactome.org/PathwayBrowser/#/R-CFA-166038 GPI-bound CD14 binds LPS IEA Canis familiaris 16412 R-CFA-166041 https://reactome.org/PathwayBrowser/#/R-CFA-166041 Transfer of LPS onto TLR4 IEA Canis familiaris 16412 R-CFA-166168 https://reactome.org/PathwayBrowser/#/R-CFA-166168 TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) IEA Canis familiaris 16412 R-CFA-166175 https://reactome.org/PathwayBrowser/#/R-CFA-166175 TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) IEA Canis familiaris 16412 R-CFA-166245 https://reactome.org/PathwayBrowser/#/R-CFA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Canis familiaris 16412 R-CFA-166271 https://reactome.org/PathwayBrowser/#/R-CFA-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Canis familiaris 16412 R-CFA-168915 https://reactome.org/PathwayBrowser/#/R-CFA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Canis familiaris 16412 R-CFA-168921 https://reactome.org/PathwayBrowser/#/R-CFA-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 IEA Canis familiaris 16412 R-CFA-169719 https://reactome.org/PathwayBrowser/#/R-CFA-169719 Secreted CD14 binds LPS IEA Canis familiaris 16412 R-CFA-2197646 https://reactome.org/PathwayBrowser/#/R-CFA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Canis familiaris 16412 R-CFA-2201293 https://reactome.org/PathwayBrowser/#/R-CFA-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Canis familiaris 16412 R-CFA-2201338 https://reactome.org/PathwayBrowser/#/R-CFA-2201338 TRAF3 binds TICAM1:activated TLR4 complex IEA Canis familiaris 16412 R-CFA-2213017 https://reactome.org/PathwayBrowser/#/R-CFA-2213017 Auto-ubiquitination of TRAF3 IEA Canis familiaris 16412 R-CFA-2247510 https://reactome.org/PathwayBrowser/#/R-CFA-2247510 MARCO:ligand is endocytosed IEA Canis familiaris 16412 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 16412 R-CFA-2512800 https://reactome.org/PathwayBrowser/#/R-CFA-2512800 SCARB1:ligand is endocytosed IEA Canis familiaris 16412 R-CFA-2559439 https://reactome.org/PathwayBrowser/#/R-CFA-2559439 CD14:LPS binds CR3 IEA Canis familiaris 16412 R-CFA-2559568 https://reactome.org/PathwayBrowser/#/R-CFA-2559568 SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 IEA Canis familiaris 16412 R-CFA-2562564 https://reactome.org/PathwayBrowser/#/R-CFA-2562564 Caspase-8 processing within TLR4 complex IEA Canis familiaris 16412 R-CFA-2569057 https://reactome.org/PathwayBrowser/#/R-CFA-2569057 RIP3 binds TRIF to mediate necroptosis IEA Canis familiaris 16412 R-CFA-450358 https://reactome.org/PathwayBrowser/#/R-CFA-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Canis familiaris 16412 R-CFA-5362486 https://reactome.org/PathwayBrowser/#/R-CFA-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 IEA Canis familiaris 16412 R-CFA-5362500 https://reactome.org/PathwayBrowser/#/R-CFA-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Canis familiaris 16412 R-CFA-6801762 https://reactome.org/PathwayBrowser/#/R-CFA-6801762 REG3A oligomerize to form a pore complex IEA Canis familiaris 16412 R-CFA-6804100 https://reactome.org/PathwayBrowser/#/R-CFA-6804100 HMGB1 binds LPS IEA Canis familiaris 16412 R-CFA-6807585 https://reactome.org/PathwayBrowser/#/R-CFA-6807585 BPI binds LPS on the bacterial surface IEA Canis familiaris 16412 R-CFA-6810724 https://reactome.org/PathwayBrowser/#/R-CFA-6810724 PI3 binds the bacterial surface IEA Canis familiaris 16412 R-CFA-936947 https://reactome.org/PathwayBrowser/#/R-CFA-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Canis familiaris 16412 R-CFA-936951 https://reactome.org/PathwayBrowser/#/R-CFA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Canis familiaris 16412 R-CFA-936952 https://reactome.org/PathwayBrowser/#/R-CFA-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex IEA Canis familiaris 16412 R-CFA-936985 https://reactome.org/PathwayBrowser/#/R-CFA-936985 Activated TLR4:TICAM1 recruits TRAF6 IEA Canis familiaris 16412 R-CFA-937029 https://reactome.org/PathwayBrowser/#/R-CFA-937029 IKBKG subunit of IKK complex binds polyubiquinated RIP1 IEA Canis familiaris 16412 R-CFA-937075 https://reactome.org/PathwayBrowser/#/R-CFA-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Canis familiaris 16412 R-CFA-9823904 https://reactome.org/PathwayBrowser/#/R-CFA-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Canis familiaris 16412 R-CFA-9823906 https://reactome.org/PathwayBrowser/#/R-CFA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Canis familiaris 16412 R-CFA-9823910 https://reactome.org/PathwayBrowser/#/R-CFA-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Canis familiaris 16412 R-CFA-9823932 https://reactome.org/PathwayBrowser/#/R-CFA-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Canis familiaris 16412 R-CFA-9823934 https://reactome.org/PathwayBrowser/#/R-CFA-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Canis familiaris 16412 R-CFA-9823939 https://reactome.org/PathwayBrowser/#/R-CFA-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Canis familiaris 16412 R-CFA-9824882 https://reactome.org/PathwayBrowser/#/R-CFA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Canis familiaris 16412 R-DDI-166015 https://reactome.org/PathwayBrowser/#/R-DDI-166015 Association of LBP with LPS IEA Dictyostelium discoideum 16412 R-DDI-6804100 https://reactome.org/PathwayBrowser/#/R-DDI-6804100 HMGB1 binds LPS IEA Dictyostelium discoideum 16412 R-DDI-6807585 https://reactome.org/PathwayBrowser/#/R-DDI-6807585 BPI binds LPS on the bacterial surface IEA Dictyostelium discoideum 16412 R-DME-6801762 https://reactome.org/PathwayBrowser/#/R-DME-6801762 REG3A oligomerize to form a pore complex IEA Drosophila melanogaster 16412 R-DME-6804100 https://reactome.org/PathwayBrowser/#/R-DME-6804100 HMGB1 binds LPS IEA Drosophila melanogaster 16412 R-DRE-6803063 https://reactome.org/PathwayBrowser/#/R-DRE-6803063 RNASEs bind bacterial LPS, PGN IEA Danio rerio 16412 R-DRE-6804100 https://reactome.org/PathwayBrowser/#/R-DRE-6804100 HMGB1 binds LPS IEA Danio rerio 16412 R-GGA-166015 https://reactome.org/PathwayBrowser/#/R-GGA-166015 Association of LBP with LPS IEA Gallus gallus 16412 R-GGA-166038 https://reactome.org/PathwayBrowser/#/R-GGA-166038 GPI-bound CD14 binds LPS IEA Gallus gallus 16412 R-GGA-166041 https://reactome.org/PathwayBrowser/#/R-GGA-166041 Transfer of LPS onto TLR4 IEA Gallus gallus 16412 R-GGA-166175 https://reactome.org/PathwayBrowser/#/R-GGA-166175 TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) IEA Gallus gallus 16412 R-GGA-166245 https://reactome.org/PathwayBrowser/#/R-GGA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Gallus gallus 16412 R-GGA-166271 https://reactome.org/PathwayBrowser/#/R-GGA-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Gallus gallus 16412 R-GGA-168915 https://reactome.org/PathwayBrowser/#/R-GGA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Gallus gallus 16412 R-GGA-168921 https://reactome.org/PathwayBrowser/#/R-GGA-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 IEA Gallus gallus 16412 R-GGA-169719 https://reactome.org/PathwayBrowser/#/R-GGA-169719 Secreted CD14 binds LPS IEA Gallus gallus 16412 R-GGA-2197646 https://reactome.org/PathwayBrowser/#/R-GGA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Gallus gallus 16412 R-GGA-2201293 https://reactome.org/PathwayBrowser/#/R-GGA-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Gallus gallus 16412 R-GGA-2201338 https://reactome.org/PathwayBrowser/#/R-GGA-2201338 TRAF3 binds TICAM1:activated TLR4 complex IEA Gallus gallus 16412 R-GGA-2203480 https://reactome.org/PathwayBrowser/#/R-GGA-2203480 COLEC11 binds ligands IEA Gallus gallus 16412 R-GGA-2213017 https://reactome.org/PathwayBrowser/#/R-GGA-2213017 Auto-ubiquitination of TRAF3 IEA Gallus gallus 16412 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 16412 R-GGA-2512800 https://reactome.org/PathwayBrowser/#/R-GGA-2512800 SCARB1:ligand is endocytosed IEA Gallus gallus 16412 R-GGA-2559439 https://reactome.org/PathwayBrowser/#/R-GGA-2559439 CD14:LPS binds CR3 IEA Gallus gallus 16412 R-GGA-2562541 https://reactome.org/PathwayBrowser/#/R-GGA-2562541 TLR4-induced ripoptosome assembly IEA Gallus gallus 16412 R-GGA-2562564 https://reactome.org/PathwayBrowser/#/R-GGA-2562564 Caspase-8 processing within TLR4 complex IEA Gallus gallus 16412 R-GGA-433864 https://reactome.org/PathwayBrowser/#/R-GGA-433864 IRAK2 binds to the IRAK4 accociated with the complex of the activated TLR : TIRAP : MyD88 IEA Gallus gallus 16412 R-GGA-433940 https://reactome.org/PathwayBrowser/#/R-GGA-433940 Association of LBP with bacterial LPS TAS Gallus gallus 16412 R-GGA-433961 https://reactome.org/PathwayBrowser/#/R-GGA-433961 Activated TLR homo- or heterodimer recruits adaptors TIRAP(or MAL) and MyD88 IEA Gallus gallus 16412 R-GGA-434003 https://reactome.org/PathwayBrowser/#/R-GGA-434003 LPS binding to CD14 co-receptor TAS Gallus gallus 16412 R-GGA-434018 https://reactome.org/PathwayBrowser/#/R-GGA-434018 Autophosphorylation of chicken IRAK4 IEA Gallus gallus 16412 R-GGA-434047 https://reactome.org/PathwayBrowser/#/R-GGA-434047 phosphorylation of IRAK2 by activated IRAK4 IEA Gallus gallus 16412 R-GGA-434053 https://reactome.org/PathwayBrowser/#/R-GGA-434053 TRAF6 binds to p-IRAK2 complexed with activated TLR IEA Gallus gallus 16412 R-GGA-434058 https://reactome.org/PathwayBrowser/#/R-GGA-434058 LPS binding to Toll like receptor 4 results in dimerization of the TLR4 associated with LY96 TAS Gallus gallus 16412 R-GGA-434073 https://reactome.org/PathwayBrowser/#/R-GGA-434073 IRAK4 recruitment to the activated TLR complexed with ligand, TIRAP and MyD88 IEA Gallus gallus 16412 R-GGA-434084 https://reactome.org/PathwayBrowser/#/R-GGA-434084 p-IRAK2- TRAF6 dissociates from the activated chTLR complex IEA Gallus gallus 16412 R-GGA-450358 https://reactome.org/PathwayBrowser/#/R-GGA-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Gallus gallus 16412 R-GGA-5362486 https://reactome.org/PathwayBrowser/#/R-GGA-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 IEA Gallus gallus 16412 R-GGA-5362500 https://reactome.org/PathwayBrowser/#/R-GGA-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus 16412 R-GGA-6803063 https://reactome.org/PathwayBrowser/#/R-GGA-6803063 RNASEs bind bacterial LPS, PGN IEA Gallus gallus 16412 R-GGA-6804100 https://reactome.org/PathwayBrowser/#/R-GGA-6804100 HMGB1 binds LPS IEA Gallus gallus 16412 R-GGA-6807585 https://reactome.org/PathwayBrowser/#/R-GGA-6807585 BPI binds LPS on the bacterial surface IEA Gallus gallus 16412 R-GGA-936947 https://reactome.org/PathwayBrowser/#/R-GGA-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Gallus gallus 16412 R-GGA-936951 https://reactome.org/PathwayBrowser/#/R-GGA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Gallus gallus 16412 R-GGA-936952 https://reactome.org/PathwayBrowser/#/R-GGA-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex IEA Gallus gallus 16412 R-GGA-936985 https://reactome.org/PathwayBrowser/#/R-GGA-936985 Activated TLR4:TICAM1 recruits TRAF6 IEA Gallus gallus 16412 R-GGA-937075 https://reactome.org/PathwayBrowser/#/R-GGA-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Gallus gallus 16412 R-GGA-9823904 https://reactome.org/PathwayBrowser/#/R-GGA-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus 16412 R-GGA-9823906 https://reactome.org/PathwayBrowser/#/R-GGA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Gallus gallus 16412 R-GGA-9823910 https://reactome.org/PathwayBrowser/#/R-GGA-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus 16412 R-GGA-9823932 https://reactome.org/PathwayBrowser/#/R-GGA-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus 16412 R-GGA-9823934 https://reactome.org/PathwayBrowser/#/R-GGA-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Gallus gallus 16412 R-GGA-9823939 https://reactome.org/PathwayBrowser/#/R-GGA-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Gallus gallus 16412 R-GGA-9824882 https://reactome.org/PathwayBrowser/#/R-GGA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Gallus gallus 16412 R-HSA-166015 https://reactome.org/PathwayBrowser/#/R-HSA-166015 Association of LBP with LPS TAS Homo sapiens 16412 R-HSA-166038 https://reactome.org/PathwayBrowser/#/R-HSA-166038 GPI-bound CD14 binds LPS TAS Homo sapiens 16412 R-HSA-166041 https://reactome.org/PathwayBrowser/#/R-HSA-166041 Transfer of LPS onto TLR4 TAS Homo sapiens 16412 R-HSA-166072 https://reactome.org/PathwayBrowser/#/R-HSA-166072 MyD88 forms a complex with TIRAP:activated TLR2/4 TAS Homo sapiens 16412 R-HSA-166082 https://reactome.org/PathwayBrowser/#/R-HSA-166082 IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex TAS Homo sapiens 16412 R-HSA-166091 https://reactome.org/PathwayBrowser/#/R-HSA-166091 IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex TAS Homo sapiens 16412 R-HSA-166119 https://reactome.org/PathwayBrowser/#/R-HSA-166119 First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal TAS Homo sapiens 16412 R-HSA-166168 https://reactome.org/PathwayBrowser/#/R-HSA-166168 TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) TAS Homo sapiens 16412 R-HSA-166175 https://reactome.org/PathwayBrowser/#/R-HSA-166175 TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) TAS Homo sapiens 16412 R-HSA-166245 https://reactome.org/PathwayBrowser/#/R-HSA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex TAS Homo sapiens 16412 R-HSA-166271 https://reactome.org/PathwayBrowser/#/R-HSA-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 TAS Homo sapiens 16412 R-HSA-166284 https://reactome.org/PathwayBrowser/#/R-HSA-166284 Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP TAS Homo sapiens 16412 R-HSA-166286 https://reactome.org/PathwayBrowser/#/R-HSA-166286 Multiple IRAK1 autophosphorylation steps TAS Homo sapiens 16412 R-HSA-166362 https://reactome.org/PathwayBrowser/#/R-HSA-166362 Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 16412 R-HSA-166363 https://reactome.org/PathwayBrowser/#/R-HSA-166363 TRAF6 binds to hp- IRAK1 TAS Homo sapiens 16412 R-HSA-168915 https://reactome.org/PathwayBrowser/#/R-HSA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex TAS Homo sapiens 16412 R-HSA-168921 https://reactome.org/PathwayBrowser/#/R-HSA-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 TAS Homo sapiens 16412 R-HSA-169719 https://reactome.org/PathwayBrowser/#/R-HSA-169719 Secreted CD14 binds LPS TAS Homo sapiens 16412 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 16412 R-HSA-2173781 https://reactome.org/PathwayBrowser/#/R-HSA-2173781 MARCO (SCARA2) binds ligands IEA Homo sapiens 16412 R-HSA-2187266 https://reactome.org/PathwayBrowser/#/R-HSA-2187266 SCARA5 binds ligands IEA Homo sapiens 16412 R-HSA-2197646 https://reactome.org/PathwayBrowser/#/R-HSA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands TAS Homo sapiens 16412 R-HSA-2201293 https://reactome.org/PathwayBrowser/#/R-HSA-2201293 Endocytosis of TLR4:LY96:LPS:CD14 TAS Homo sapiens 16412 R-HSA-2201316 https://reactome.org/PathwayBrowser/#/R-HSA-2201316 Activated TLR2/4 interacts with MAL (TIRAP) TAS Homo sapiens 16412 R-HSA-2201322 https://reactome.org/PathwayBrowser/#/R-HSA-2201322 TIRAP is phosphorylated by BTK TAS Homo sapiens 16412 R-HSA-2201338 https://reactome.org/PathwayBrowser/#/R-HSA-2201338 TRAF3 binds TICAM1:activated TLR4 complex TAS Homo sapiens 16412 R-HSA-2203480 https://reactome.org/PathwayBrowser/#/R-HSA-2203480 COLEC11 binds ligands TAS Homo sapiens 16412 R-HSA-2213017 https://reactome.org/PathwayBrowser/#/R-HSA-2213017 Auto-ubiquitination of TRAF3 TAS Homo sapiens 16412 R-HSA-2247510 https://reactome.org/PathwayBrowser/#/R-HSA-2247510 MARCO:ligand is endocytosed TAS Homo sapiens 16412 R-HSA-2262775 https://reactome.org/PathwayBrowser/#/R-HSA-2262775 Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 16412 R-HSA-2262777 https://reactome.org/PathwayBrowser/#/R-HSA-2262777 TRAF6 binds to p-IRAK2 TAS Homo sapiens 16412 R-HSA-2299677 https://reactome.org/PathwayBrowser/#/R-HSA-2299677 SCARA5:ligand is endocytosed IEA Homo sapiens 16412 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 16412 R-HSA-2512800 https://reactome.org/PathwayBrowser/#/R-HSA-2512800 SCARB1:ligand is endocytosed TAS Homo sapiens 16412 R-HSA-2559414 https://reactome.org/PathwayBrowser/#/R-HSA-2559414 Activated TLR2/4:TIRAP interacts with BTK TAS Homo sapiens 16412 R-HSA-2559439 https://reactome.org/PathwayBrowser/#/R-HSA-2559439 CD14:LPS binds CR3 TAS Homo sapiens 16412 R-HSA-2559568 https://reactome.org/PathwayBrowser/#/R-HSA-2559568 SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 TAS Homo sapiens 16412 R-HSA-2562541 https://reactome.org/PathwayBrowser/#/R-HSA-2562541 TLR4-induced ripoptosome assembly TAS Homo sapiens 16412 R-HSA-2562564 https://reactome.org/PathwayBrowser/#/R-HSA-2562564 Caspase-8 processing within TLR4 complex TAS Homo sapiens 16412 R-HSA-2569057 https://reactome.org/PathwayBrowser/#/R-HSA-2569057 RIP3 binds TRIF to mediate necroptosis TAS Homo sapiens 16412 R-HSA-450358 https://reactome.org/PathwayBrowser/#/R-HSA-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation TAS Homo sapiens 16412 R-HSA-5362486 https://reactome.org/PathwayBrowser/#/R-HSA-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 TAS Homo sapiens 16412 R-HSA-5362500 https://reactome.org/PathwayBrowser/#/R-HSA-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 TAS Homo sapiens 16412 R-HSA-5602353 https://reactome.org/PathwayBrowser/#/R-HSA-5602353 Defective IRAK4 variants do not bind MyD88:MAL:BTK:activated TLR2/4 TAS Homo sapiens 16412 R-HSA-5602383 https://reactome.org/PathwayBrowser/#/R-HSA-5602383 Defective MyD88 does not oligomerize within the activated TLR2/4 complex TAS Homo sapiens 16412 R-HSA-5602606 https://reactome.org/PathwayBrowser/#/R-HSA-5602606 Defective MyD88 does not bind MAL(TIRAP):TLR2/4 TAS Homo sapiens 16412 R-HSA-5602672 https://reactome.org/PathwayBrowser/#/R-HSA-5602672 Defective IRAK4 does not bind MyD88 within the TLR2/4 complex TAS Homo sapiens 16412 R-HSA-6801762 https://reactome.org/PathwayBrowser/#/R-HSA-6801762 REG3A oligomerize to form a pore complex TAS Homo sapiens 16412 R-HSA-6803063 https://reactome.org/PathwayBrowser/#/R-HSA-6803063 RNASEs bind bacterial LPS, PGN TAS Homo sapiens 16412 R-HSA-6804100 https://reactome.org/PathwayBrowser/#/R-HSA-6804100 HMGB1 binds LPS TAS Homo sapiens 16412 R-HSA-6807585 https://reactome.org/PathwayBrowser/#/R-HSA-6807585 BPI binds LPS on the bacterial surface TAS Homo sapiens 16412 R-HSA-6810724 https://reactome.org/PathwayBrowser/#/R-HSA-6810724 PI3 binds the bacterial surface TAS Homo sapiens 16412 R-HSA-8863895 https://reactome.org/PathwayBrowser/#/R-HSA-8863895 IKKB phosphorylates SNAP23 TAS Homo sapiens 16412 R-HSA-936947 https://reactome.org/PathwayBrowser/#/R-HSA-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex TAS Homo sapiens 16412 R-HSA-936951 https://reactome.org/PathwayBrowser/#/R-HSA-936951 Activation of TAK1 complex bound to activated TLR4 complex TAS Homo sapiens 16412 R-HSA-936952 https://reactome.org/PathwayBrowser/#/R-HSA-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex TAS Homo sapiens 16412 R-HSA-936985 https://reactome.org/PathwayBrowser/#/R-HSA-936985 Activated TLR4:TICAM1 recruits TRAF6 TAS Homo sapiens 16412 R-HSA-937022 https://reactome.org/PathwayBrowser/#/R-HSA-937022 IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP TAS Homo sapiens 16412 R-HSA-937029 https://reactome.org/PathwayBrowser/#/R-HSA-937029 IKBKG subunit of IKK complex binds polyubiquinated RIP1 TAS Homo sapiens 16412 R-HSA-937059 https://reactome.org/PathwayBrowser/#/R-HSA-937059 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex TAS Homo sapiens 16412 R-HSA-937075 https://reactome.org/PathwayBrowser/#/R-HSA-937075 Phosphorylated TAK1 leaves activated TLR receptor complex TAS Homo sapiens 16412 R-HSA-937079 https://reactome.org/PathwayBrowser/#/R-HSA-937079 MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 TAS Homo sapiens 16412 R-HSA-9823904 https://reactome.org/PathwayBrowser/#/R-HSA-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 TAS Homo sapiens 16412 R-HSA-9823906 https://reactome.org/PathwayBrowser/#/R-HSA-9823906 TBK1 is phosphorylated within the activated TLR4 complex TAS Homo sapiens 16412 R-HSA-9823910 https://reactome.org/PathwayBrowser/#/R-HSA-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 TAS Homo sapiens 16412 R-HSA-9823932 https://reactome.org/PathwayBrowser/#/R-HSA-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 TAS Homo sapiens 16412 R-HSA-9823934 https://reactome.org/PathwayBrowser/#/R-HSA-9823934 OPTN binds TBK1 within the activated TLR4 complex TAS Homo sapiens 16412 R-HSA-9823939 https://reactome.org/PathwayBrowser/#/R-HSA-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 TAS Homo sapiens 16412 R-HSA-9824882 https://reactome.org/PathwayBrowser/#/R-HSA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex TAS Homo sapiens 16412 R-MMU-166015 https://reactome.org/PathwayBrowser/#/R-MMU-166015 Association of LBP with LPS IEA Mus musculus 16412 R-MMU-166038 https://reactome.org/PathwayBrowser/#/R-MMU-166038 GPI-bound CD14 binds LPS IEA Mus musculus 16412 R-MMU-166041 https://reactome.org/PathwayBrowser/#/R-MMU-166041 Transfer of LPS onto TLR4 IEA Mus musculus 16412 R-MMU-166168 https://reactome.org/PathwayBrowser/#/R-MMU-166168 TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) IEA Mus musculus 16412 R-MMU-166175 https://reactome.org/PathwayBrowser/#/R-MMU-166175 TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) IEA Mus musculus 16412 R-MMU-166245 https://reactome.org/PathwayBrowser/#/R-MMU-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Mus musculus 16412 R-MMU-166271 https://reactome.org/PathwayBrowser/#/R-MMU-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Mus musculus 16412 R-MMU-168915 https://reactome.org/PathwayBrowser/#/R-MMU-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Mus musculus 16412 R-MMU-168921 https://reactome.org/PathwayBrowser/#/R-MMU-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 IEA Mus musculus 16412 R-MMU-169719 https://reactome.org/PathwayBrowser/#/R-MMU-169719 Secreted CD14 binds LPS IEA Mus musculus 16412 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 16412 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 16412 R-MMU-2187267 https://reactome.org/PathwayBrowser/#/R-MMU-2187267 Scara5 binds ligands TAS Mus musculus 16412 R-MMU-2197646 https://reactome.org/PathwayBrowser/#/R-MMU-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Mus musculus 16412 R-MMU-2201293 https://reactome.org/PathwayBrowser/#/R-MMU-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Mus musculus 16412 R-MMU-2201338 https://reactome.org/PathwayBrowser/#/R-MMU-2201338 TRAF3 binds TICAM1:activated TLR4 complex IEA Mus musculus 16412 R-MMU-2203480 https://reactome.org/PathwayBrowser/#/R-MMU-2203480 COLEC11 binds ligands IEA Mus musculus 16412 R-MMU-2213017 https://reactome.org/PathwayBrowser/#/R-MMU-2213017 Auto-ubiquitination of TRAF3 IEA Mus musculus 16412 R-MMU-2247510 https://reactome.org/PathwayBrowser/#/R-MMU-2247510 MARCO:ligand is endocytosed IEA Mus musculus 16412 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 16412 R-MMU-2512800 https://reactome.org/PathwayBrowser/#/R-MMU-2512800 SCARB1:ligand is endocytosed IEA Mus musculus 16412 R-MMU-2559439 https://reactome.org/PathwayBrowser/#/R-MMU-2559439 CD14:LPS binds CR3 IEA Mus musculus 16412 R-MMU-2559568 https://reactome.org/PathwayBrowser/#/R-MMU-2559568 SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 IEA Mus musculus 16412 R-MMU-2562541 https://reactome.org/PathwayBrowser/#/R-MMU-2562541 TLR4-induced ripoptosome assembly IEA Mus musculus 16412 R-MMU-2562564 https://reactome.org/PathwayBrowser/#/R-MMU-2562564 Caspase-8 processing within TLR4 complex IEA Mus musculus 16412 R-MMU-2569057 https://reactome.org/PathwayBrowser/#/R-MMU-2569057 RIP3 binds TRIF to mediate necroptosis IEA Mus musculus 16412 R-MMU-450358 https://reactome.org/PathwayBrowser/#/R-MMU-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Mus musculus 16412 R-MMU-5362486 https://reactome.org/PathwayBrowser/#/R-MMU-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 IEA Mus musculus 16412 R-MMU-5362500 https://reactome.org/PathwayBrowser/#/R-MMU-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Mus musculus 16412 R-MMU-6801762 https://reactome.org/PathwayBrowser/#/R-MMU-6801762 REG3A oligomerize to form a pore complex IEA Mus musculus 16412 R-MMU-6803063 https://reactome.org/PathwayBrowser/#/R-MMU-6803063 RNASEs bind bacterial LPS, PGN IEA Mus musculus 16412 R-MMU-6804100 https://reactome.org/PathwayBrowser/#/R-MMU-6804100 HMGB1 binds LPS IEA Mus musculus 16412 R-MMU-6807585 https://reactome.org/PathwayBrowser/#/R-MMU-6807585 BPI binds LPS on the bacterial surface IEA Mus musculus 16412 R-MMU-8878599 https://reactome.org/PathwayBrowser/#/R-MMU-8878599 Ssc5d binds ligands TAS Mus musculus 16412 R-MMU-936947 https://reactome.org/PathwayBrowser/#/R-MMU-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Mus musculus 16412 R-MMU-936951 https://reactome.org/PathwayBrowser/#/R-MMU-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Mus musculus 16412 R-MMU-936952 https://reactome.org/PathwayBrowser/#/R-MMU-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex IEA Mus musculus 16412 R-MMU-936985 https://reactome.org/PathwayBrowser/#/R-MMU-936985 Activated TLR4:TICAM1 recruits TRAF6 IEA Mus musculus 16412 R-MMU-937029 https://reactome.org/PathwayBrowser/#/R-MMU-937029 IKBKG subunit of IKK complex binds polyubiquinated RIP1 IEA Mus musculus 16412 R-MMU-937075 https://reactome.org/PathwayBrowser/#/R-MMU-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Mus musculus 16412 R-MMU-9823904 https://reactome.org/PathwayBrowser/#/R-MMU-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Mus musculus 16412 R-MMU-9823906 https://reactome.org/PathwayBrowser/#/R-MMU-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Mus musculus 16412 R-MMU-9823910 https://reactome.org/PathwayBrowser/#/R-MMU-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Mus musculus 16412 R-MMU-9823932 https://reactome.org/PathwayBrowser/#/R-MMU-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Mus musculus 16412 R-MMU-9823934 https://reactome.org/PathwayBrowser/#/R-MMU-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Mus musculus 16412 R-MMU-9823939 https://reactome.org/PathwayBrowser/#/R-MMU-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Mus musculus 16412 R-MMU-9824882 https://reactome.org/PathwayBrowser/#/R-MMU-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Mus musculus 16412 R-PFA-6804100 https://reactome.org/PathwayBrowser/#/R-PFA-6804100 HMGB1 binds LPS IEA Plasmodium falciparum 16412 R-RNO-166015 https://reactome.org/PathwayBrowser/#/R-RNO-166015 Association of LBP with LPS IEA Rattus norvegicus 16412 R-RNO-166038 https://reactome.org/PathwayBrowser/#/R-RNO-166038 GPI-bound CD14 binds LPS IEA Rattus norvegicus 16412 R-RNO-166041 https://reactome.org/PathwayBrowser/#/R-RNO-166041 Transfer of LPS onto TLR4 IEA Rattus norvegicus 16412 R-RNO-166168 https://reactome.org/PathwayBrowser/#/R-RNO-166168 TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) IEA Rattus norvegicus 16412 R-RNO-166175 https://reactome.org/PathwayBrowser/#/R-RNO-166175 TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) IEA Rattus norvegicus 16412 R-RNO-166245 https://reactome.org/PathwayBrowser/#/R-RNO-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Rattus norvegicus 16412 R-RNO-166271 https://reactome.org/PathwayBrowser/#/R-RNO-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Rattus norvegicus 16412 R-RNO-168915 https://reactome.org/PathwayBrowser/#/R-RNO-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Rattus norvegicus 16412 R-RNO-168921 https://reactome.org/PathwayBrowser/#/R-RNO-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 IEA Rattus norvegicus 16412 R-RNO-169719 https://reactome.org/PathwayBrowser/#/R-RNO-169719 Secreted CD14 binds LPS IEA Rattus norvegicus 16412 R-RNO-2197646 https://reactome.org/PathwayBrowser/#/R-RNO-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Rattus norvegicus 16412 R-RNO-2201293 https://reactome.org/PathwayBrowser/#/R-RNO-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Rattus norvegicus 16412 R-RNO-2201338 https://reactome.org/PathwayBrowser/#/R-RNO-2201338 TRAF3 binds TICAM1:activated TLR4 complex IEA Rattus norvegicus 16412 R-RNO-2213017 https://reactome.org/PathwayBrowser/#/R-RNO-2213017 Auto-ubiquitination of TRAF3 IEA Rattus norvegicus 16412 R-RNO-2247510 https://reactome.org/PathwayBrowser/#/R-RNO-2247510 MARCO:ligand is endocytosed IEA Rattus norvegicus 16412 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 16412 R-RNO-2512800 https://reactome.org/PathwayBrowser/#/R-RNO-2512800 SCARB1:ligand is endocytosed IEA Rattus norvegicus 16412 R-RNO-2559568 https://reactome.org/PathwayBrowser/#/R-RNO-2559568 SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 IEA Rattus norvegicus 16412 R-RNO-2562541 https://reactome.org/PathwayBrowser/#/R-RNO-2562541 TLR4-induced ripoptosome assembly IEA Rattus norvegicus 16412 R-RNO-2562564 https://reactome.org/PathwayBrowser/#/R-RNO-2562564 Caspase-8 processing within TLR4 complex IEA Rattus norvegicus 16412 R-RNO-2569057 https://reactome.org/PathwayBrowser/#/R-RNO-2569057 RIP3 binds TRIF to mediate necroptosis IEA Rattus norvegicus 16412 R-RNO-450358 https://reactome.org/PathwayBrowser/#/R-RNO-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Rattus norvegicus 16412 R-RNO-5362486 https://reactome.org/PathwayBrowser/#/R-RNO-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 IEA Rattus norvegicus 16412 R-RNO-5362500 https://reactome.org/PathwayBrowser/#/R-RNO-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus 16412 R-RNO-6801762 https://reactome.org/PathwayBrowser/#/R-RNO-6801762 REG3A oligomerize to form a pore complex IEA Rattus norvegicus 16412 R-RNO-6803063 https://reactome.org/PathwayBrowser/#/R-RNO-6803063 RNASEs bind bacterial LPS, PGN IEA Rattus norvegicus 16412 R-RNO-6804100 https://reactome.org/PathwayBrowser/#/R-RNO-6804100 HMGB1 binds LPS IEA Rattus norvegicus 16412 R-RNO-6807585 https://reactome.org/PathwayBrowser/#/R-RNO-6807585 BPI binds LPS on the bacterial surface IEA Rattus norvegicus 16412 R-RNO-936947 https://reactome.org/PathwayBrowser/#/R-RNO-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Rattus norvegicus 16412 R-RNO-936951 https://reactome.org/PathwayBrowser/#/R-RNO-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Rattus norvegicus 16412 R-RNO-936952 https://reactome.org/PathwayBrowser/#/R-RNO-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex IEA Rattus norvegicus 16412 R-RNO-936985 https://reactome.org/PathwayBrowser/#/R-RNO-936985 Activated TLR4:TICAM1 recruits TRAF6 IEA Rattus norvegicus 16412 R-RNO-937029 https://reactome.org/PathwayBrowser/#/R-RNO-937029 IKBKG subunit of IKK complex binds polyubiquinated RIP1 IEA Rattus norvegicus 16412 R-RNO-937075 https://reactome.org/PathwayBrowser/#/R-RNO-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Rattus norvegicus 16412 R-RNO-9823904 https://reactome.org/PathwayBrowser/#/R-RNO-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus 16412 R-RNO-9823906 https://reactome.org/PathwayBrowser/#/R-RNO-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Rattus norvegicus 16412 R-RNO-9823910 https://reactome.org/PathwayBrowser/#/R-RNO-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus 16412 R-RNO-9823932 https://reactome.org/PathwayBrowser/#/R-RNO-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus 16412 R-RNO-9823934 https://reactome.org/PathwayBrowser/#/R-RNO-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Rattus norvegicus 16412 R-RNO-9823939 https://reactome.org/PathwayBrowser/#/R-RNO-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Rattus norvegicus 16412 R-RNO-9824882 https://reactome.org/PathwayBrowser/#/R-RNO-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Rattus norvegicus 16412 R-SCE-6804100 https://reactome.org/PathwayBrowser/#/R-SCE-6804100 HMGB1 binds LPS IEA Saccharomyces cerevisiae 16412 R-SPO-6804100 https://reactome.org/PathwayBrowser/#/R-SPO-6804100 HMGB1 binds LPS IEA Schizosaccharomyces pombe 16412 R-SSC-166015 https://reactome.org/PathwayBrowser/#/R-SSC-166015 Association of LBP with LPS IEA Sus scrofa 16412 R-SSC-166038 https://reactome.org/PathwayBrowser/#/R-SSC-166038 GPI-bound CD14 binds LPS IEA Sus scrofa 16412 R-SSC-166041 https://reactome.org/PathwayBrowser/#/R-SSC-166041 Transfer of LPS onto TLR4 IEA Sus scrofa 16412 R-SSC-166168 https://reactome.org/PathwayBrowser/#/R-SSC-166168 TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) IEA Sus scrofa 16412 R-SSC-166175 https://reactome.org/PathwayBrowser/#/R-SSC-166175 TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) IEA Sus scrofa 16412 R-SSC-166245 https://reactome.org/PathwayBrowser/#/R-SSC-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Sus scrofa 16412 R-SSC-166271 https://reactome.org/PathwayBrowser/#/R-SSC-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Sus scrofa 16412 R-SSC-168915 https://reactome.org/PathwayBrowser/#/R-SSC-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Sus scrofa 16412 R-SSC-168921 https://reactome.org/PathwayBrowser/#/R-SSC-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 IEA Sus scrofa 16412 R-SSC-169719 https://reactome.org/PathwayBrowser/#/R-SSC-169719 Secreted CD14 binds LPS IEA Sus scrofa 16412 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa 16412 R-SSC-2201293 https://reactome.org/PathwayBrowser/#/R-SSC-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Sus scrofa 16412 R-SSC-2201338 https://reactome.org/PathwayBrowser/#/R-SSC-2201338 TRAF3 binds TICAM1:activated TLR4 complex IEA Sus scrofa 16412 R-SSC-2203480 https://reactome.org/PathwayBrowser/#/R-SSC-2203480 COLEC11 binds ligands IEA Sus scrofa 16412 R-SSC-2213017 https://reactome.org/PathwayBrowser/#/R-SSC-2213017 Auto-ubiquitination of TRAF3 IEA Sus scrofa 16412 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 16412 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa 16412 R-SSC-2559439 https://reactome.org/PathwayBrowser/#/R-SSC-2559439 CD14:LPS binds CR3 IEA Sus scrofa 16412 R-SSC-2562541 https://reactome.org/PathwayBrowser/#/R-SSC-2562541 TLR4-induced ripoptosome assembly IEA Sus scrofa 16412 R-SSC-2562564 https://reactome.org/PathwayBrowser/#/R-SSC-2562564 Caspase-8 processing within TLR4 complex IEA Sus scrofa 16412 R-SSC-2569057 https://reactome.org/PathwayBrowser/#/R-SSC-2569057 RIP3 binds TRIF to mediate necroptosis IEA Sus scrofa 16412 R-SSC-450358 https://reactome.org/PathwayBrowser/#/R-SSC-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Sus scrofa 16412 R-SSC-5362486 https://reactome.org/PathwayBrowser/#/R-SSC-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 IEA Sus scrofa 16412 R-SSC-5362500 https://reactome.org/PathwayBrowser/#/R-SSC-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Sus scrofa 16412 R-SSC-6801762 https://reactome.org/PathwayBrowser/#/R-SSC-6801762 REG3A oligomerize to form a pore complex IEA Sus scrofa 16412 R-SSC-6803063 https://reactome.org/PathwayBrowser/#/R-SSC-6803063 RNASEs bind bacterial LPS, PGN IEA Sus scrofa 16412 R-SSC-6807585 https://reactome.org/PathwayBrowser/#/R-SSC-6807585 BPI binds LPS on the bacterial surface IEA Sus scrofa 16412 R-SSC-6810724 https://reactome.org/PathwayBrowser/#/R-SSC-6810724 PI3 binds the bacterial surface IEA Sus scrofa 16412 R-SSC-936947 https://reactome.org/PathwayBrowser/#/R-SSC-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Sus scrofa 16412 R-SSC-936951 https://reactome.org/PathwayBrowser/#/R-SSC-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Sus scrofa 16412 R-SSC-936952 https://reactome.org/PathwayBrowser/#/R-SSC-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex IEA Sus scrofa 16412 R-SSC-936985 https://reactome.org/PathwayBrowser/#/R-SSC-936985 Activated TLR4:TICAM1 recruits TRAF6 IEA Sus scrofa 16412 R-SSC-937029 https://reactome.org/PathwayBrowser/#/R-SSC-937029 IKBKG subunit of IKK complex binds polyubiquinated RIP1 IEA Sus scrofa 16412 R-SSC-937075 https://reactome.org/PathwayBrowser/#/R-SSC-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Sus scrofa 16412 R-SSC-9823904 https://reactome.org/PathwayBrowser/#/R-SSC-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Sus scrofa 16412 R-SSC-9823906 https://reactome.org/PathwayBrowser/#/R-SSC-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Sus scrofa 16412 R-SSC-9823910 https://reactome.org/PathwayBrowser/#/R-SSC-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Sus scrofa 16412 R-SSC-9823932 https://reactome.org/PathwayBrowser/#/R-SSC-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Sus scrofa 16412 R-SSC-9823934 https://reactome.org/PathwayBrowser/#/R-SSC-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Sus scrofa 16412 R-SSC-9823939 https://reactome.org/PathwayBrowser/#/R-SSC-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Sus scrofa 16412 R-SSC-9824882 https://reactome.org/PathwayBrowser/#/R-SSC-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Sus scrofa 16412 R-XTR-166015 https://reactome.org/PathwayBrowser/#/R-XTR-166015 Association of LBP with LPS IEA Xenopus tropicalis 16412 R-XTR-6801762 https://reactome.org/PathwayBrowser/#/R-XTR-6801762 REG3A oligomerize to form a pore complex IEA Xenopus tropicalis 16412 R-XTR-6804100 https://reactome.org/PathwayBrowser/#/R-XTR-6804100 HMGB1 binds LPS IEA Xenopus tropicalis 16412 R-XTR-6807585 https://reactome.org/PathwayBrowser/#/R-XTR-6807585 BPI binds LPS on the bacterial surface IEA Xenopus tropicalis 16422 R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 16422 R-BTA-193064 https://reactome.org/PathwayBrowser/#/R-BTA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Bos taurus 16422 R-BTA-193073 https://reactome.org/PathwayBrowser/#/R-BTA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Bos taurus 16422 R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 16422 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 16422 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 16422 R-BTA-5625717 https://reactome.org/PathwayBrowser/#/R-BTA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Bos taurus 16422 R-BTA-5625738 https://reactome.org/PathwayBrowser/#/R-BTA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Bos taurus 16422 R-BTA-5625745 https://reactome.org/PathwayBrowser/#/R-BTA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Bos taurus 16422 R-BTA-5625774 https://reactome.org/PathwayBrowser/#/R-BTA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Bos taurus 16422 R-BTA-5625784 https://reactome.org/PathwayBrowser/#/R-BTA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Bos taurus 16422 R-BTA-5625796 https://reactome.org/PathwayBrowser/#/R-BTA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Bos taurus 16422 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 16422 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 16422 R-BTA-5625849 https://reactome.org/PathwayBrowser/#/R-BTA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Bos taurus 16422 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 16422 R-BTA-8877902 https://reactome.org/PathwayBrowser/#/R-BTA-8877902 Activated AR binds RUNX2 IEA Bos taurus 16422 R-BTA-9705925 https://reactome.org/PathwayBrowser/#/R-BTA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Bos taurus 16422 R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 16422 R-CEL-193064 https://reactome.org/PathwayBrowser/#/R-CEL-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Caenorhabditis elegans 16422 R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 16422 R-CFA-193073 https://reactome.org/PathwayBrowser/#/R-CFA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Canis familiaris 16422 R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 16422 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 16422 R-CFA-5625717 https://reactome.org/PathwayBrowser/#/R-CFA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Canis familiaris 16422 R-CFA-5625738 https://reactome.org/PathwayBrowser/#/R-CFA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Canis familiaris 16422 R-CFA-5625745 https://reactome.org/PathwayBrowser/#/R-CFA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Canis familiaris 16422 R-CFA-5625774 https://reactome.org/PathwayBrowser/#/R-CFA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Canis familiaris 16422 R-CFA-5625784 https://reactome.org/PathwayBrowser/#/R-CFA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Canis familiaris 16422 R-CFA-5625796 https://reactome.org/PathwayBrowser/#/R-CFA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Canis familiaris 16422 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 16422 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 16422 R-CFA-5625849 https://reactome.org/PathwayBrowser/#/R-CFA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Canis familiaris 16422 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 16422 R-CFA-8877902 https://reactome.org/PathwayBrowser/#/R-CFA-8877902 Activated AR binds RUNX2 IEA Canis familiaris 16422 R-CFA-9705925 https://reactome.org/PathwayBrowser/#/R-CFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Canis familiaris 16422 R-DDI-193064 https://reactome.org/PathwayBrowser/#/R-DDI-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Dictyostelium discoideum 16422 R-DDI-5625784 https://reactome.org/PathwayBrowser/#/R-DDI-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Dictyostelium discoideum 16422 R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 16422 R-DME-193064 https://reactome.org/PathwayBrowser/#/R-DME-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Drosophila melanogaster 16422 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 16422 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 16422 R-DME-5625717 https://reactome.org/PathwayBrowser/#/R-DME-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Drosophila melanogaster 16422 R-DME-5625738 https://reactome.org/PathwayBrowser/#/R-DME-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Drosophila melanogaster 16422 R-DME-5625745 https://reactome.org/PathwayBrowser/#/R-DME-5625745 PKN1 stimulates association of AR with NCOA2 IEA Drosophila melanogaster 16422 R-DME-5625774 https://reactome.org/PathwayBrowser/#/R-DME-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Drosophila melanogaster 16422 R-DME-5625784 https://reactome.org/PathwayBrowser/#/R-DME-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Drosophila melanogaster 16422 R-DME-5625796 https://reactome.org/PathwayBrowser/#/R-DME-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 16422 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 16422 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 16422 R-DME-5625849 https://reactome.org/PathwayBrowser/#/R-DME-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 16422 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 16422 R-DME-8877902 https://reactome.org/PathwayBrowser/#/R-DME-8877902 Activated AR binds RUNX2 IEA Drosophila melanogaster 16422 R-DME-9705925 https://reactome.org/PathwayBrowser/#/R-DME-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Drosophila melanogaster 16422 R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 16422 R-DRE-193064 https://reactome.org/PathwayBrowser/#/R-DRE-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Danio rerio 16422 R-DRE-193073 https://reactome.org/PathwayBrowser/#/R-DRE-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Danio rerio 16422 R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 16422 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 16422 R-DRE-5625717 https://reactome.org/PathwayBrowser/#/R-DRE-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Danio rerio 16422 R-DRE-5625738 https://reactome.org/PathwayBrowser/#/R-DRE-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Danio rerio 16422 R-DRE-5625745 https://reactome.org/PathwayBrowser/#/R-DRE-5625745 PKN1 stimulates association of AR with NCOA2 IEA Danio rerio 16422 R-DRE-5625774 https://reactome.org/PathwayBrowser/#/R-DRE-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Danio rerio 16422 R-DRE-5625784 https://reactome.org/PathwayBrowser/#/R-DRE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Danio rerio 16422 R-DRE-5625796 https://reactome.org/PathwayBrowser/#/R-DRE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Danio rerio 16422 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 16422 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 16422 R-DRE-8877902 https://reactome.org/PathwayBrowser/#/R-DRE-8877902 Activated AR binds RUNX2 IEA Danio rerio 16422 R-DRE-9705925 https://reactome.org/PathwayBrowser/#/R-DRE-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Danio rerio 16422 R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 16422 R-GGA-193064 https://reactome.org/PathwayBrowser/#/R-GGA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Gallus gallus 16422 R-GGA-193073 https://reactome.org/PathwayBrowser/#/R-GGA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Gallus gallus 16422 R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 16422 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 16422 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 16422 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus 16422 R-GGA-5625796 https://reactome.org/PathwayBrowser/#/R-GGA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Gallus gallus 16422 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 16422 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 16422 R-GGA-5625849 https://reactome.org/PathwayBrowser/#/R-GGA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Gallus gallus 16422 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 16422 R-GGA-8877902 https://reactome.org/PathwayBrowser/#/R-GGA-8877902 Activated AR binds RUNX2 IEA Gallus gallus 16422 R-GGA-9705925 https://reactome.org/PathwayBrowser/#/R-GGA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Gallus gallus 16422 R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 16422 R-HSA-193064 https://reactome.org/PathwayBrowser/#/R-HSA-193064 HSD17B3-like proteins reducde ANDST to TEST TAS Homo sapiens 16422 R-HSA-193073 https://reactome.org/PathwayBrowser/#/R-HSA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST TAS Homo sapiens 16422 R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 16422 R-HSA-5601849 https://reactome.org/PathwayBrowser/#/R-HSA-5601849 Defective CYP19A1 does not convert ANDST to E1 TAS Homo sapiens 16422 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 16422 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 16422 R-HSA-5625717 https://reactome.org/PathwayBrowser/#/R-HSA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) TAS Homo sapiens 16422 R-HSA-5625738 https://reactome.org/PathwayBrowser/#/R-HSA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus TAS Homo sapiens 16422 R-HSA-5625745 https://reactome.org/PathwayBrowser/#/R-HSA-5625745 PKN1 stimulates association of AR with NCOA2 TAS Homo sapiens 16422 R-HSA-5625774 https://reactome.org/PathwayBrowser/#/R-HSA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes TAS Homo sapiens 16422 R-HSA-5625784 https://reactome.org/PathwayBrowser/#/R-HSA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters TAS Homo sapiens 16422 R-HSA-5625796 https://reactome.org/PathwayBrowser/#/R-HSA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters TAS Homo sapiens 16422 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 16422 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 16422 R-HSA-5625849 https://reactome.org/PathwayBrowser/#/R-HSA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters TAS Homo sapiens 16422 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 16422 R-HSA-5625883 https://reactome.org/PathwayBrowser/#/R-HSA-5625883 PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 TAS Homo sapiens 16422 R-HSA-8877902 https://reactome.org/PathwayBrowser/#/R-HSA-8877902 Activated AR binds RUNX2 TAS Homo sapiens 16422 R-HSA-8877918 https://reactome.org/PathwayBrowser/#/R-HSA-8877918 RUNX2:MAF complex binds the BGLAP gene promoter IEA Homo sapiens 16422 R-HSA-9705925 https://reactome.org/PathwayBrowser/#/R-HSA-9705925 Androgens binds AR (in the HSP90 chaperone complex) TAS Homo sapiens 16422 R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 16422 R-MMU-193064 https://reactome.org/PathwayBrowser/#/R-MMU-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Mus musculus 16422 R-MMU-193073 https://reactome.org/PathwayBrowser/#/R-MMU-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Mus musculus 16422 R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 16422 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 16422 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 16422 R-MMU-5625717 https://reactome.org/PathwayBrowser/#/R-MMU-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Mus musculus 16422 R-MMU-5625738 https://reactome.org/PathwayBrowser/#/R-MMU-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Mus musculus 16422 R-MMU-5625745 https://reactome.org/PathwayBrowser/#/R-MMU-5625745 PKN1 stimulates association of AR with NCOA2 IEA Mus musculus 16422 R-MMU-8877902 https://reactome.org/PathwayBrowser/#/R-MMU-8877902 Activated AR binds RUNX2 IEA Mus musculus 16422 R-MMU-9705925 https://reactome.org/PathwayBrowser/#/R-MMU-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Mus musculus 16422 R-PFA-193064 https://reactome.org/PathwayBrowser/#/R-PFA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Plasmodium falciparum 16422 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 16422 R-PFA-9705925 https://reactome.org/PathwayBrowser/#/R-PFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Plasmodium falciparum 16422 R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 16422 R-RNO-193064 https://reactome.org/PathwayBrowser/#/R-RNO-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Rattus norvegicus 16422 R-RNO-193073 https://reactome.org/PathwayBrowser/#/R-RNO-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Rattus norvegicus 16422 R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 16422 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 16422 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 16422 R-RNO-5625717 https://reactome.org/PathwayBrowser/#/R-RNO-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Rattus norvegicus 16422 R-RNO-5625738 https://reactome.org/PathwayBrowser/#/R-RNO-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Rattus norvegicus 16422 R-RNO-5625745 https://reactome.org/PathwayBrowser/#/R-RNO-5625745 PKN1 stimulates association of AR with NCOA2 IEA Rattus norvegicus 16422 R-RNO-5625774 https://reactome.org/PathwayBrowser/#/R-RNO-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Rattus norvegicus 16422 R-RNO-5625784 https://reactome.org/PathwayBrowser/#/R-RNO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Rattus norvegicus 16422 R-RNO-5625796 https://reactome.org/PathwayBrowser/#/R-RNO-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Rattus norvegicus 16422 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 16422 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 16422 R-RNO-5625849 https://reactome.org/PathwayBrowser/#/R-RNO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Rattus norvegicus 16422 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 16422 R-RNO-9705925 https://reactome.org/PathwayBrowser/#/R-RNO-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Rattus norvegicus 16422 R-SCE-5625784 https://reactome.org/PathwayBrowser/#/R-SCE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16422 R-SCE-5625796 https://reactome.org/PathwayBrowser/#/R-SCE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16422 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16422 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16422 R-SCE-5625849 https://reactome.org/PathwayBrowser/#/R-SCE-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16422 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16422 R-SPO-5625784 https://reactome.org/PathwayBrowser/#/R-SPO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16422 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16422 R-SPO-5625849 https://reactome.org/PathwayBrowser/#/R-SPO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16422 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16422 R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 16422 R-SSC-193064 https://reactome.org/PathwayBrowser/#/R-SSC-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Sus scrofa 16422 R-SSC-193073 https://reactome.org/PathwayBrowser/#/R-SSC-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Sus scrofa 16422 R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 16422 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 16422 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 16422 R-SSC-5625717 https://reactome.org/PathwayBrowser/#/R-SSC-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Sus scrofa 16422 R-SSC-5625738 https://reactome.org/PathwayBrowser/#/R-SSC-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Sus scrofa 16422 R-SSC-5625745 https://reactome.org/PathwayBrowser/#/R-SSC-5625745 PKN1 stimulates association of AR with NCOA2 IEA Sus scrofa 16422 R-SSC-5625774 https://reactome.org/PathwayBrowser/#/R-SSC-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Sus scrofa 16422 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa 16422 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa 16422 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 16422 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 16422 R-SSC-5625849 https://reactome.org/PathwayBrowser/#/R-SSC-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Sus scrofa 16422 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 16422 R-SSC-8877902 https://reactome.org/PathwayBrowser/#/R-SSC-8877902 Activated AR binds RUNX2 IEA Sus scrofa 16422 R-SSC-9705925 https://reactome.org/PathwayBrowser/#/R-SSC-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Sus scrofa 16422 R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 16422 R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 16422 R-XTR-8877902 https://reactome.org/PathwayBrowser/#/R-XTR-8877902 Activated AR binds RUNX2 IEA Xenopus tropicalis 16422 R-XTR-9705925 https://reactome.org/PathwayBrowser/#/R-XTR-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Xenopus tropicalis 16424 R-BTA-141200 https://reactome.org/PathwayBrowser/#/R-BTA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Bos taurus 16424 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 16424 R-CFA-141200 https://reactome.org/PathwayBrowser/#/R-CFA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Canis familiaris 16424 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 16424 R-DDI-141200 https://reactome.org/PathwayBrowser/#/R-DDI-141200 MAOB:FAD oxidatively deaminates of PEA IEA Dictyostelium discoideum 16424 R-DRE-141200 https://reactome.org/PathwayBrowser/#/R-DRE-141200 MAOB:FAD oxidatively deaminates of PEA IEA Danio rerio 16424 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 16424 R-GGA-141200 https://reactome.org/PathwayBrowser/#/R-GGA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Gallus gallus 16424 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 16424 R-HSA-141200 https://reactome.org/PathwayBrowser/#/R-HSA-141200 MAOB:FAD oxidatively deaminates of PEA TAS Homo sapiens 16424 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 16424 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 16424 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 16424 R-MMU-141200 https://reactome.org/PathwayBrowser/#/R-MMU-141200 MAOB:FAD oxidatively deaminates of PEA IEA Mus musculus 16424 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 16424 R-RNO-141200 https://reactome.org/PathwayBrowser/#/R-RNO-141200 MAOB:FAD oxidatively deaminates of PEA IEA Rattus norvegicus 16424 R-SSC-141200 https://reactome.org/PathwayBrowser/#/R-SSC-141200 MAOB:FAD oxidatively deaminates of PEA IEA Sus scrofa 16424 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 16424 R-XTR-141200 https://reactome.org/PathwayBrowser/#/R-XTR-141200 MAOB:FAD oxidatively deaminates of PEA IEA Xenopus tropicalis 16427 R-BTA-159179 https://reactome.org/PathwayBrowser/#/R-BTA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Bos taurus 16427 R-BTA-159194 https://reactome.org/PathwayBrowser/#/R-BTA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Bos taurus 16427 R-BTA-5679041 https://reactome.org/PathwayBrowser/#/R-BTA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 16427 R-BTA-9661417 https://reactome.org/PathwayBrowser/#/R-BTA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 16427 R-CEL-5679041 https://reactome.org/PathwayBrowser/#/R-CEL-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 16427 R-CEL-9661417 https://reactome.org/PathwayBrowser/#/R-CEL-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 16427 R-CFA-5679041 https://reactome.org/PathwayBrowser/#/R-CFA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 16427 R-CFA-9661417 https://reactome.org/PathwayBrowser/#/R-CFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 16427 R-DDI-159179 https://reactome.org/PathwayBrowser/#/R-DDI-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Dictyostelium discoideum 16427 R-DDI-159194 https://reactome.org/PathwayBrowser/#/R-DDI-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Dictyostelium discoideum 16427 R-DDI-5679041 https://reactome.org/PathwayBrowser/#/R-DDI-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 16427 R-DDI-9632038 https://reactome.org/PathwayBrowser/#/R-DDI-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Dictyostelium discoideum 16427 R-DDI-9632039 https://reactome.org/PathwayBrowser/#/R-DDI-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Dictyostelium discoideum 16427 R-DDI-9661417 https://reactome.org/PathwayBrowser/#/R-DDI-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 16427 R-DME-5679041 https://reactome.org/PathwayBrowser/#/R-DME-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 16427 R-DME-9661417 https://reactome.org/PathwayBrowser/#/R-DME-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 16427 R-DRE-5679041 https://reactome.org/PathwayBrowser/#/R-DRE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Danio rerio 16427 R-GGA-159179 https://reactome.org/PathwayBrowser/#/R-GGA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Gallus gallus 16427 R-GGA-159194 https://reactome.org/PathwayBrowser/#/R-GGA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Gallus gallus 16427 R-GGA-5679041 https://reactome.org/PathwayBrowser/#/R-GGA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Gallus gallus 16427 R-GGA-9632038 https://reactome.org/PathwayBrowser/#/R-GGA-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Gallus gallus 16427 R-GGA-9632039 https://reactome.org/PathwayBrowser/#/R-GGA-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Gallus gallus 16427 R-HSA-159179 https://reactome.org/PathwayBrowser/#/R-HSA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG TAS Homo sapiens 16427 R-HSA-159194 https://reactome.org/PathwayBrowser/#/R-HSA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG TAS Homo sapiens 16427 R-HSA-5679031 https://reactome.org/PathwayBrowser/#/R-HSA-5679031 Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region TAS Homo sapiens 16427 R-HSA-5679041 https://reactome.org/PathwayBrowser/#/R-HSA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 16427 R-HSA-9036102 https://reactome.org/PathwayBrowser/#/R-HSA-9036102 Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BMG TAS Homo sapiens 16427 R-HSA-9036104 https://reactome.org/PathwayBrowser/#/R-HSA-9036104 Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BMG TAS Homo sapiens 16427 R-HSA-9632038 https://reactome.org/PathwayBrowser/#/R-HSA-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG TAS Homo sapiens 16427 R-HSA-9632039 https://reactome.org/PathwayBrowser/#/R-HSA-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG TAS Homo sapiens 16427 R-HSA-9661417 https://reactome.org/PathwayBrowser/#/R-HSA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 16427 R-HSA-9661446 https://reactome.org/PathwayBrowser/#/R-HSA-9661446 BMG, BDG translocates from ER lumen to cytosol TAS Homo sapiens 16427 R-MMU-159179 https://reactome.org/PathwayBrowser/#/R-MMU-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Mus musculus 16427 R-MMU-159194 https://reactome.org/PathwayBrowser/#/R-MMU-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Mus musculus 16427 R-MMU-5679041 https://reactome.org/PathwayBrowser/#/R-MMU-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 16427 R-MMU-9632038 https://reactome.org/PathwayBrowser/#/R-MMU-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Mus musculus 16427 R-MMU-9632039 https://reactome.org/PathwayBrowser/#/R-MMU-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Mus musculus 16427 R-MMU-9661417 https://reactome.org/PathwayBrowser/#/R-MMU-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 16427 R-PFA-9661417 https://reactome.org/PathwayBrowser/#/R-PFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Plasmodium falciparum 16427 R-RNO-159179 https://reactome.org/PathwayBrowser/#/R-RNO-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Rattus norvegicus 16427 R-RNO-159194 https://reactome.org/PathwayBrowser/#/R-RNO-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Rattus norvegicus 16427 R-RNO-5679041 https://reactome.org/PathwayBrowser/#/R-RNO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 16427 R-RNO-9632038 https://reactome.org/PathwayBrowser/#/R-RNO-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Rattus norvegicus 16427 R-RNO-9632039 https://reactome.org/PathwayBrowser/#/R-RNO-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Rattus norvegicus 16427 R-RNO-9661417 https://reactome.org/PathwayBrowser/#/R-RNO-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 16427 R-SCE-5679041 https://reactome.org/PathwayBrowser/#/R-SCE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 16427 R-SCE-9661417 https://reactome.org/PathwayBrowser/#/R-SCE-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 16427 R-SPO-5679041 https://reactome.org/PathwayBrowser/#/R-SPO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Schizosaccharomyces pombe 16427 R-SSC-159179 https://reactome.org/PathwayBrowser/#/R-SSC-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Sus scrofa 16427 R-SSC-159194 https://reactome.org/PathwayBrowser/#/R-SSC-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Sus scrofa 16427 R-SSC-5679041 https://reactome.org/PathwayBrowser/#/R-SSC-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 16427 R-SSC-9661417 https://reactome.org/PathwayBrowser/#/R-SSC-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 16427 R-XTR-5679041 https://reactome.org/PathwayBrowser/#/R-XTR-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 16427 R-XTR-9661417 https://reactome.org/PathwayBrowser/#/R-XTR-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 16436 R-BTA-1482961 https://reactome.org/PathwayBrowser/#/R-BTA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Bos taurus 16436 R-BTA-1482973 https://reactome.org/PathwayBrowser/#/R-BTA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Bos taurus 16436 R-BTA-1483081 https://reactome.org/PathwayBrowser/#/R-BTA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Bos taurus 16436 R-CEL-1482961 https://reactome.org/PathwayBrowser/#/R-CEL-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Caenorhabditis elegans 16436 R-CEL-1482973 https://reactome.org/PathwayBrowser/#/R-CEL-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Caenorhabditis elegans 16436 R-CEL-1483081 https://reactome.org/PathwayBrowser/#/R-CEL-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Caenorhabditis elegans 16436 R-CFA-1482961 https://reactome.org/PathwayBrowser/#/R-CFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Canis familiaris 16436 R-CFA-1482973 https://reactome.org/PathwayBrowser/#/R-CFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Canis familiaris 16436 R-CFA-1483081 https://reactome.org/PathwayBrowser/#/R-CFA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Canis familiaris 16436 R-DDI-1482961 https://reactome.org/PathwayBrowser/#/R-DDI-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Dictyostelium discoideum 16436 R-DDI-1482973 https://reactome.org/PathwayBrowser/#/R-DDI-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Dictyostelium discoideum 16436 R-DDI-1483081 https://reactome.org/PathwayBrowser/#/R-DDI-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Dictyostelium discoideum 16436 R-DME-1482961 https://reactome.org/PathwayBrowser/#/R-DME-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Drosophila melanogaster 16436 R-DME-1482973 https://reactome.org/PathwayBrowser/#/R-DME-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Drosophila melanogaster 16436 R-DME-1483081 https://reactome.org/PathwayBrowser/#/R-DME-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Drosophila melanogaster 16436 R-DRE-1482961 https://reactome.org/PathwayBrowser/#/R-DRE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Danio rerio 16436 R-DRE-1482973 https://reactome.org/PathwayBrowser/#/R-DRE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Danio rerio 16436 R-DRE-1483081 https://reactome.org/PathwayBrowser/#/R-DRE-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Danio rerio 16436 R-GGA-1482961 https://reactome.org/PathwayBrowser/#/R-GGA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Gallus gallus 16436 R-GGA-1482973 https://reactome.org/PathwayBrowser/#/R-GGA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Gallus gallus 16436 R-GGA-1483081 https://reactome.org/PathwayBrowser/#/R-GGA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Gallus gallus 16436 R-HSA-1482961 https://reactome.org/PathwayBrowser/#/R-HSA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane TAS Homo sapiens 16436 R-HSA-1482973 https://reactome.org/PathwayBrowser/#/R-HSA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane TAS Homo sapiens 16436 R-HSA-1483081 https://reactome.org/PathwayBrowser/#/R-HSA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer TAS Homo sapiens 16436 R-MMU-1482961 https://reactome.org/PathwayBrowser/#/R-MMU-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Mus musculus 16436 R-MMU-1482973 https://reactome.org/PathwayBrowser/#/R-MMU-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Mus musculus 16436 R-MMU-1483081 https://reactome.org/PathwayBrowser/#/R-MMU-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Mus musculus 16436 R-PFA-1482961 https://reactome.org/PathwayBrowser/#/R-PFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Plasmodium falciparum 16436 R-PFA-1482973 https://reactome.org/PathwayBrowser/#/R-PFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Plasmodium falciparum 16436 R-PFA-1483081 https://reactome.org/PathwayBrowser/#/R-PFA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Plasmodium falciparum 16436 R-RNO-1482961 https://reactome.org/PathwayBrowser/#/R-RNO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Rattus norvegicus 16436 R-RNO-1482973 https://reactome.org/PathwayBrowser/#/R-RNO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Rattus norvegicus 16436 R-RNO-1483081 https://reactome.org/PathwayBrowser/#/R-RNO-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Rattus norvegicus 16436 R-SCE-1482961 https://reactome.org/PathwayBrowser/#/R-SCE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Saccharomyces cerevisiae 16436 R-SCE-1482973 https://reactome.org/PathwayBrowser/#/R-SCE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Saccharomyces cerevisiae 16436 R-SCE-1483081 https://reactome.org/PathwayBrowser/#/R-SCE-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Saccharomyces cerevisiae 16436 R-SPO-1482961 https://reactome.org/PathwayBrowser/#/R-SPO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Schizosaccharomyces pombe 16436 R-SPO-1482973 https://reactome.org/PathwayBrowser/#/R-SPO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Schizosaccharomyces pombe 16436 R-SPO-1483081 https://reactome.org/PathwayBrowser/#/R-SPO-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Schizosaccharomyces pombe 16436 R-SSC-1482961 https://reactome.org/PathwayBrowser/#/R-SSC-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Sus scrofa 16436 R-SSC-1482973 https://reactome.org/PathwayBrowser/#/R-SSC-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Sus scrofa 16436 R-SSC-1483081 https://reactome.org/PathwayBrowser/#/R-SSC-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Sus scrofa 16436 R-XTR-1482961 https://reactome.org/PathwayBrowser/#/R-XTR-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Xenopus tropicalis 16436 R-XTR-1482973 https://reactome.org/PathwayBrowser/#/R-XTR-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Xenopus tropicalis 16436 R-XTR-1483081 https://reactome.org/PathwayBrowser/#/R-XTR-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Xenopus tropicalis 16450 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 16450 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 16450 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 16450 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 16450 R-BTA-109759 https://reactome.org/PathwayBrowser/#/R-BTA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Bos taurus 16450 R-BTA-73608 https://reactome.org/PathwayBrowser/#/R-BTA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Bos taurus 16450 R-BTA-74372 https://reactome.org/PathwayBrowser/#/R-BTA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Bos taurus 16450 R-BTA-74376 https://reactome.org/PathwayBrowser/#/R-BTA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Bos taurus 16450 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 16450 R-CEL-73608 https://reactome.org/PathwayBrowser/#/R-CEL-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Caenorhabditis elegans 16450 R-CEL-74372 https://reactome.org/PathwayBrowser/#/R-CEL-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Caenorhabditis elegans 16450 R-CEL-74376 https://reactome.org/PathwayBrowser/#/R-CEL-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Caenorhabditis elegans 16450 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 16450 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 16450 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 16450 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 16450 R-CFA-109759 https://reactome.org/PathwayBrowser/#/R-CFA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Canis familiaris 16450 R-CFA-73608 https://reactome.org/PathwayBrowser/#/R-CFA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Canis familiaris 16450 R-CFA-74372 https://reactome.org/PathwayBrowser/#/R-CFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Canis familiaris 16450 R-CFA-74376 https://reactome.org/PathwayBrowser/#/R-CFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Canis familiaris 16450 R-DDI-73608 https://reactome.org/PathwayBrowser/#/R-DDI-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Dictyostelium discoideum 16450 R-DDI-74372 https://reactome.org/PathwayBrowser/#/R-DDI-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Dictyostelium discoideum 16450 R-DDI-74376 https://reactome.org/PathwayBrowser/#/R-DDI-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Dictyostelium discoideum 16450 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 16450 R-DME-109759 https://reactome.org/PathwayBrowser/#/R-DME-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Drosophila melanogaster 16450 R-DME-73608 https://reactome.org/PathwayBrowser/#/R-DME-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Drosophila melanogaster 16450 R-DME-74372 https://reactome.org/PathwayBrowser/#/R-DME-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Drosophila melanogaster 16450 R-DME-74376 https://reactome.org/PathwayBrowser/#/R-DME-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Drosophila melanogaster 16450 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 16450 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 16450 R-DRE-73608 https://reactome.org/PathwayBrowser/#/R-DRE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Danio rerio 16450 R-DRE-74372 https://reactome.org/PathwayBrowser/#/R-DRE-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Danio rerio 16450 R-DRE-74376 https://reactome.org/PathwayBrowser/#/R-DRE-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Danio rerio 16450 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 16450 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 16450 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 16450 R-GGA-109759 https://reactome.org/PathwayBrowser/#/R-GGA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Gallus gallus 16450 R-GGA-73608 https://reactome.org/PathwayBrowser/#/R-GGA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Gallus gallus 16450 R-GGA-74372 https://reactome.org/PathwayBrowser/#/R-GGA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Gallus gallus 16450 R-GGA-74376 https://reactome.org/PathwayBrowser/#/R-GGA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Gallus gallus 16450 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 16450 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 16450 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 16450 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 16450 R-HSA-109759 https://reactome.org/PathwayBrowser/#/R-HSA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] TAS Homo sapiens 16450 R-HSA-112265 https://reactome.org/PathwayBrowser/#/R-HSA-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] TAS Homo sapiens 16450 R-HSA-112266 https://reactome.org/PathwayBrowser/#/R-HSA-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] TAS Homo sapiens 16450 R-HSA-73608 https://reactome.org/PathwayBrowser/#/R-HSA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) TAS Homo sapiens 16450 R-HSA-74372 https://reactome.org/PathwayBrowser/#/R-HSA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] TAS Homo sapiens 16450 R-HSA-74376 https://reactome.org/PathwayBrowser/#/R-HSA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) TAS Homo sapiens 16450 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 16450 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 16450 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 16450 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 16450 R-MMU-109759 https://reactome.org/PathwayBrowser/#/R-MMU-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Mus musculus 16450 R-MMU-112265 https://reactome.org/PathwayBrowser/#/R-MMU-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Mus musculus 16450 R-MMU-112266 https://reactome.org/PathwayBrowser/#/R-MMU-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Mus musculus 16450 R-MMU-73608 https://reactome.org/PathwayBrowser/#/R-MMU-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Mus musculus 16450 R-MMU-74372 https://reactome.org/PathwayBrowser/#/R-MMU-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Mus musculus 16450 R-MMU-74376 https://reactome.org/PathwayBrowser/#/R-MMU-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Mus musculus 16450 R-PFA-74372 https://reactome.org/PathwayBrowser/#/R-PFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Plasmodium falciparum 16450 R-PFA-74376 https://reactome.org/PathwayBrowser/#/R-PFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Plasmodium falciparum 16450 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 16450 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 16450 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 16450 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 16450 R-RNO-109759 https://reactome.org/PathwayBrowser/#/R-RNO-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Rattus norvegicus 16450 R-RNO-112265 https://reactome.org/PathwayBrowser/#/R-RNO-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Rattus norvegicus 16450 R-RNO-112266 https://reactome.org/PathwayBrowser/#/R-RNO-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Rattus norvegicus 16450 R-RNO-73608 https://reactome.org/PathwayBrowser/#/R-RNO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Rattus norvegicus 16450 R-RNO-74372 https://reactome.org/PathwayBrowser/#/R-RNO-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Rattus norvegicus 16450 R-RNO-74376 https://reactome.org/PathwayBrowser/#/R-RNO-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Rattus norvegicus 16450 R-SCE-73608 https://reactome.org/PathwayBrowser/#/R-SCE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Saccharomyces cerevisiae 16450 R-SPO-73608 https://reactome.org/PathwayBrowser/#/R-SPO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Schizosaccharomyces pombe 16450 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 16450 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 16450 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 16450 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 16450 R-SSC-109759 https://reactome.org/PathwayBrowser/#/R-SSC-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Sus scrofa 16450 R-SSC-73608 https://reactome.org/PathwayBrowser/#/R-SSC-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Sus scrofa 16450 R-SSC-74372 https://reactome.org/PathwayBrowser/#/R-SSC-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Sus scrofa 16450 R-SSC-74376 https://reactome.org/PathwayBrowser/#/R-SSC-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Sus scrofa 16450 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 16450 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 16450 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 16450 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 16450 R-XTR-109759 https://reactome.org/PathwayBrowser/#/R-XTR-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Xenopus tropicalis 16450 R-XTR-112265 https://reactome.org/PathwayBrowser/#/R-XTR-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Xenopus tropicalis 16450 R-XTR-112266 https://reactome.org/PathwayBrowser/#/R-XTR-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Xenopus tropicalis 16450 R-XTR-73608 https://reactome.org/PathwayBrowser/#/R-XTR-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Xenopus tropicalis 16450 R-XTR-74372 https://reactome.org/PathwayBrowser/#/R-XTR-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Xenopus tropicalis 16450 R-XTR-74376 https://reactome.org/PathwayBrowser/#/R-XTR-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Xenopus tropicalis 16452 R-BTA-372819 https://reactome.org/PathwayBrowser/#/R-BTA-372819 PCK2 phosphorylates OA to yield PEP IEA Bos taurus 16452 R-BTA-6784393 https://reactome.org/PathwayBrowser/#/R-BTA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Bos taurus 16452 R-BTA-6810076 https://reactome.org/PathwayBrowser/#/R-BTA-6810076 DDO oxidizes D-Asp to OA IEA Bos taurus 16452 R-BTA-70241 https://reactome.org/PathwayBrowser/#/R-BTA-70241 PCK1 phosphorylates OA to yield PEP IEA Bos taurus 16452 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 16452 R-BTA-70581 https://reactome.org/PathwayBrowser/#/R-BTA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Bos taurus 16452 R-BTA-70592 https://reactome.org/PathwayBrowser/#/R-BTA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Bos taurus 16452 R-BTA-70596 https://reactome.org/PathwayBrowser/#/R-BTA-70596 GOT2 dimer deaminates L-Asp IEA Bos taurus 16452 R-BTA-70613 https://reactome.org/PathwayBrowser/#/R-BTA-70613 GOT2 transaminates OA and L-Glu IEA Bos taurus 16452 R-BTA-70975 https://reactome.org/PathwayBrowser/#/R-BTA-70975 CS acetylates OA to citrate IEA Bos taurus 16452 R-BTA-70979 https://reactome.org/PathwayBrowser/#/R-BTA-70979 MDH2 dimer dehydrogenates MAL IEA Bos taurus 16452 R-BTA-75848 https://reactome.org/PathwayBrowser/#/R-BTA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Bos taurus 16452 R-BTA-9012016 https://reactome.org/PathwayBrowser/#/R-BTA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Bos taurus 16452 R-BTA-9854315 https://reactome.org/PathwayBrowser/#/R-BTA-9854315 CSKMT methylates Citrate Synthase IEA Bos taurus 16452 R-BTA-9856871 https://reactome.org/PathwayBrowser/#/R-BTA-9856871 MDH1 reduces OA IEA Bos taurus 16452 R-BTA-9861660 https://reactome.org/PathwayBrowser/#/R-BTA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Bos taurus 16452 R-CEL-372819 https://reactome.org/PathwayBrowser/#/R-CEL-372819 PCK2 phosphorylates OA to yield PEP IEA Caenorhabditis elegans 16452 R-CEL-6784393 https://reactome.org/PathwayBrowser/#/R-CEL-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Caenorhabditis elegans 16452 R-CEL-6810076 https://reactome.org/PathwayBrowser/#/R-CEL-6810076 DDO oxidizes D-Asp to OA IEA Caenorhabditis elegans 16452 R-CEL-70241 https://reactome.org/PathwayBrowser/#/R-CEL-70241 PCK1 phosphorylates OA to yield PEP IEA Caenorhabditis elegans 16452 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 16452 R-CEL-70581 https://reactome.org/PathwayBrowser/#/R-CEL-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Caenorhabditis elegans 16452 R-CEL-70592 https://reactome.org/PathwayBrowser/#/R-CEL-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Caenorhabditis elegans 16452 R-CEL-70596 https://reactome.org/PathwayBrowser/#/R-CEL-70596 GOT2 dimer deaminates L-Asp IEA Caenorhabditis elegans 16452 R-CEL-70613 https://reactome.org/PathwayBrowser/#/R-CEL-70613 GOT2 transaminates OA and L-Glu IEA Caenorhabditis elegans 16452 R-CEL-70975 https://reactome.org/PathwayBrowser/#/R-CEL-70975 CS acetylates OA to citrate IEA Caenorhabditis elegans 16452 R-CEL-70979 https://reactome.org/PathwayBrowser/#/R-CEL-70979 MDH2 dimer dehydrogenates MAL IEA Caenorhabditis elegans 16452 R-CEL-75848 https://reactome.org/PathwayBrowser/#/R-CEL-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Caenorhabditis elegans 16452 R-CEL-9012016 https://reactome.org/PathwayBrowser/#/R-CEL-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Caenorhabditis elegans 16452 R-CEL-9856871 https://reactome.org/PathwayBrowser/#/R-CEL-9856871 MDH1 reduces OA IEA Caenorhabditis elegans 16452 R-CEL-9861660 https://reactome.org/PathwayBrowser/#/R-CEL-9861660 ME1 tetramer decarboxylates OA to PYR IEA Caenorhabditis elegans 16452 R-CFA-372819 https://reactome.org/PathwayBrowser/#/R-CFA-372819 PCK2 phosphorylates OA to yield PEP IEA Canis familiaris 16452 R-CFA-6784393 https://reactome.org/PathwayBrowser/#/R-CFA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Canis familiaris 16452 R-CFA-6810076 https://reactome.org/PathwayBrowser/#/R-CFA-6810076 DDO oxidizes D-Asp to OA IEA Canis familiaris 16452 R-CFA-70241 https://reactome.org/PathwayBrowser/#/R-CFA-70241 PCK1 phosphorylates OA to yield PEP IEA Canis familiaris 16452 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 16452 R-CFA-70581 https://reactome.org/PathwayBrowser/#/R-CFA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Canis familiaris 16452 R-CFA-70592 https://reactome.org/PathwayBrowser/#/R-CFA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Canis familiaris 16452 R-CFA-70596 https://reactome.org/PathwayBrowser/#/R-CFA-70596 GOT2 dimer deaminates L-Asp IEA Canis familiaris 16452 R-CFA-70613 https://reactome.org/PathwayBrowser/#/R-CFA-70613 GOT2 transaminates OA and L-Glu IEA Canis familiaris 16452 R-CFA-70975 https://reactome.org/PathwayBrowser/#/R-CFA-70975 CS acetylates OA to citrate IEA Canis familiaris 16452 R-CFA-70979 https://reactome.org/PathwayBrowser/#/R-CFA-70979 MDH2 dimer dehydrogenates MAL IEA Canis familiaris 16452 R-CFA-75848 https://reactome.org/PathwayBrowser/#/R-CFA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Canis familiaris 16452 R-CFA-9012016 https://reactome.org/PathwayBrowser/#/R-CFA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Canis familiaris 16452 R-CFA-9854315 https://reactome.org/PathwayBrowser/#/R-CFA-9854315 CSKMT methylates Citrate Synthase IEA Canis familiaris 16452 R-CFA-9856871 https://reactome.org/PathwayBrowser/#/R-CFA-9856871 MDH1 reduces OA IEA Canis familiaris 16452 R-CFA-9861660 https://reactome.org/PathwayBrowser/#/R-CFA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Canis familiaris 16452 R-DDI-372819 https://reactome.org/PathwayBrowser/#/R-DDI-372819 PCK2 phosphorylates OA to yield PEP IEA Dictyostelium discoideum 16452 R-DDI-6784393 https://reactome.org/PathwayBrowser/#/R-DDI-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Dictyostelium discoideum 16452 R-DDI-6810076 https://reactome.org/PathwayBrowser/#/R-DDI-6810076 DDO oxidizes D-Asp to OA IEA Dictyostelium discoideum 16452 R-DDI-70241 https://reactome.org/PathwayBrowser/#/R-DDI-70241 PCK1 phosphorylates OA to yield PEP IEA Dictyostelium discoideum 16452 R-DDI-70596 https://reactome.org/PathwayBrowser/#/R-DDI-70596 GOT2 dimer deaminates L-Asp IEA Dictyostelium discoideum 16452 R-DDI-70613 https://reactome.org/PathwayBrowser/#/R-DDI-70613 GOT2 transaminates OA and L-Glu IEA Dictyostelium discoideum 16452 R-DDI-70975 https://reactome.org/PathwayBrowser/#/R-DDI-70975 CS acetylates OA to citrate IEA Dictyostelium discoideum 16452 R-DDI-75848 https://reactome.org/PathwayBrowser/#/R-DDI-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Dictyostelium discoideum 16452 R-DDI-9012016 https://reactome.org/PathwayBrowser/#/R-DDI-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Dictyostelium discoideum 16452 R-DDI-9856871 https://reactome.org/PathwayBrowser/#/R-DDI-9856871 MDH1 reduces OA IEA Dictyostelium discoideum 16452 R-DME-372819 https://reactome.org/PathwayBrowser/#/R-DME-372819 PCK2 phosphorylates OA to yield PEP IEA Drosophila melanogaster 16452 R-DME-6784393 https://reactome.org/PathwayBrowser/#/R-DME-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Drosophila melanogaster 16452 R-DME-6810076 https://reactome.org/PathwayBrowser/#/R-DME-6810076 DDO oxidizes D-Asp to OA IEA Drosophila melanogaster 16452 R-DME-70241 https://reactome.org/PathwayBrowser/#/R-DME-70241 PCK1 phosphorylates OA to yield PEP IEA Drosophila melanogaster 16452 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 16452 R-DME-70581 https://reactome.org/PathwayBrowser/#/R-DME-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Drosophila melanogaster 16452 R-DME-70592 https://reactome.org/PathwayBrowser/#/R-DME-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Drosophila melanogaster 16452 R-DME-70596 https://reactome.org/PathwayBrowser/#/R-DME-70596 GOT2 dimer deaminates L-Asp IEA Drosophila melanogaster 16452 R-DME-70613 https://reactome.org/PathwayBrowser/#/R-DME-70613 GOT2 transaminates OA and L-Glu IEA Drosophila melanogaster 16452 R-DME-70975 https://reactome.org/PathwayBrowser/#/R-DME-70975 CS acetylates OA to citrate IEA Drosophila melanogaster 16452 R-DME-70979 https://reactome.org/PathwayBrowser/#/R-DME-70979 MDH2 dimer dehydrogenates MAL IEA Drosophila melanogaster 16452 R-DME-75848 https://reactome.org/PathwayBrowser/#/R-DME-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Drosophila melanogaster 16452 R-DME-9012016 https://reactome.org/PathwayBrowser/#/R-DME-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Drosophila melanogaster 16452 R-DME-9856871 https://reactome.org/PathwayBrowser/#/R-DME-9856871 MDH1 reduces OA IEA Drosophila melanogaster 16452 R-DME-9861660 https://reactome.org/PathwayBrowser/#/R-DME-9861660 ME1 tetramer decarboxylates OA to PYR IEA Drosophila melanogaster 16452 R-DRE-372819 https://reactome.org/PathwayBrowser/#/R-DRE-372819 PCK2 phosphorylates OA to yield PEP IEA Danio rerio 16452 R-DRE-6784393 https://reactome.org/PathwayBrowser/#/R-DRE-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Danio rerio 16452 R-DRE-70241 https://reactome.org/PathwayBrowser/#/R-DRE-70241 PCK1 phosphorylates OA to yield PEP IEA Danio rerio 16452 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 16452 R-DRE-70581 https://reactome.org/PathwayBrowser/#/R-DRE-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Danio rerio 16452 R-DRE-70592 https://reactome.org/PathwayBrowser/#/R-DRE-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Danio rerio 16452 R-DRE-70596 https://reactome.org/PathwayBrowser/#/R-DRE-70596 GOT2 dimer deaminates L-Asp IEA Danio rerio 16452 R-DRE-70613 https://reactome.org/PathwayBrowser/#/R-DRE-70613 GOT2 transaminates OA and L-Glu IEA Danio rerio 16452 R-DRE-70975 https://reactome.org/PathwayBrowser/#/R-DRE-70975 CS acetylates OA to citrate IEA Danio rerio 16452 R-DRE-70979 https://reactome.org/PathwayBrowser/#/R-DRE-70979 MDH2 dimer dehydrogenates MAL IEA Danio rerio 16452 R-DRE-75848 https://reactome.org/PathwayBrowser/#/R-DRE-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Danio rerio 16452 R-DRE-9012016 https://reactome.org/PathwayBrowser/#/R-DRE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Danio rerio 16452 R-DRE-9854315 https://reactome.org/PathwayBrowser/#/R-DRE-9854315 CSKMT methylates Citrate Synthase IEA Danio rerio 16452 R-DRE-9856871 https://reactome.org/PathwayBrowser/#/R-DRE-9856871 MDH1 reduces OA IEA Danio rerio 16452 R-DRE-9861660 https://reactome.org/PathwayBrowser/#/R-DRE-9861660 ME1 tetramer decarboxylates OA to PYR IEA Danio rerio 16452 R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 16452 R-GGA-372422 https://reactome.org/PathwayBrowser/#/R-GGA-372422 oxaloacetate + NADH + H+ <=> malate + NAD+ TAS Gallus gallus 16452 R-GGA-372559 https://reactome.org/PathwayBrowser/#/R-GGA-372559 aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate TAS Gallus gallus 16452 R-GGA-372564 https://reactome.org/PathwayBrowser/#/R-GGA-372564 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) TAS Gallus gallus 16452 R-GGA-372717 https://reactome.org/PathwayBrowser/#/R-GGA-372717 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) TAS Gallus gallus 16452 R-GGA-372719 https://reactome.org/PathwayBrowser/#/R-GGA-372719 aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate TAS Gallus gallus 16452 R-GGA-372724 https://reactome.org/PathwayBrowser/#/R-GGA-372724 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] TAS Gallus gallus 16452 R-GGA-372741 https://reactome.org/PathwayBrowser/#/R-GGA-372741 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] TAS Gallus gallus 16452 R-GGA-372819 https://reactome.org/PathwayBrowser/#/R-GGA-372819 PCK2 phosphorylates OA to yield PEP IEA Gallus gallus 16452 R-GGA-372855 https://reactome.org/PathwayBrowser/#/R-GGA-372855 malate + NAD+ <=> oxaloacetate + NADH + H+ TAS Gallus gallus 16452 R-GGA-373006 https://reactome.org/PathwayBrowser/#/R-GGA-373006 acetyl-CoA + H2O + oxaloacetate => citrate + CoA TAS Gallus gallus 16452 R-GGA-373047 https://reactome.org/PathwayBrowser/#/R-GGA-373047 malate + NAD+ <=> oxaloacetate + NADH + H+ IEA Gallus gallus 16452 R-GGA-6784393 https://reactome.org/PathwayBrowser/#/R-GGA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Gallus gallus 16452 R-GGA-6810076 https://reactome.org/PathwayBrowser/#/R-GGA-6810076 DDO oxidizes D-Asp to OA IEA Gallus gallus 16452 R-GGA-70241 https://reactome.org/PathwayBrowser/#/R-GGA-70241 PCK1 phosphorylates OA to yield PEP IEA Gallus gallus 16452 R-GGA-70581 https://reactome.org/PathwayBrowser/#/R-GGA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Gallus gallus 16452 R-GGA-70592 https://reactome.org/PathwayBrowser/#/R-GGA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Gallus gallus 16452 R-GGA-70596 https://reactome.org/PathwayBrowser/#/R-GGA-70596 GOT2 dimer deaminates L-Asp IEA Gallus gallus 16452 R-GGA-70613 https://reactome.org/PathwayBrowser/#/R-GGA-70613 GOT2 transaminates OA and L-Glu IEA Gallus gallus 16452 R-GGA-70975 https://reactome.org/PathwayBrowser/#/R-GGA-70975 CS acetylates OA to citrate IEA Gallus gallus 16452 R-GGA-70979 https://reactome.org/PathwayBrowser/#/R-GGA-70979 MDH2 dimer dehydrogenates MAL IEA Gallus gallus 16452 R-GGA-75848 https://reactome.org/PathwayBrowser/#/R-GGA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Gallus gallus 16452 R-GGA-9012016 https://reactome.org/PathwayBrowser/#/R-GGA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Gallus gallus 16452 R-GGA-9856871 https://reactome.org/PathwayBrowser/#/R-GGA-9856871 MDH1 reduces OA IEA Gallus gallus 16452 R-GGA-9861660 https://reactome.org/PathwayBrowser/#/R-GGA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Gallus gallus 16452 R-HSA-372819 https://reactome.org/PathwayBrowser/#/R-HSA-372819 PCK2 phosphorylates OA to yield PEP TAS Homo sapiens 16452 R-HSA-6784393 https://reactome.org/PathwayBrowser/#/R-HSA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) TAS Homo sapiens 16452 R-HSA-6810076 https://reactome.org/PathwayBrowser/#/R-HSA-6810076 DDO oxidizes D-Asp to OA TAS Homo sapiens 16452 R-HSA-70241 https://reactome.org/PathwayBrowser/#/R-HSA-70241 PCK1 phosphorylates OA to yield PEP TAS Homo sapiens 16452 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 16452 R-HSA-70581 https://reactome.org/PathwayBrowser/#/R-HSA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] TAS Homo sapiens 16452 R-HSA-70592 https://reactome.org/PathwayBrowser/#/R-HSA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp TAS Homo sapiens 16452 R-HSA-70596 https://reactome.org/PathwayBrowser/#/R-HSA-70596 GOT2 dimer deaminates L-Asp TAS Homo sapiens 16452 R-HSA-70613 https://reactome.org/PathwayBrowser/#/R-HSA-70613 GOT2 transaminates OA and L-Glu TAS Homo sapiens 16452 R-HSA-70975 https://reactome.org/PathwayBrowser/#/R-HSA-70975 CS acetylates OA to citrate TAS Homo sapiens 16452 R-HSA-70979 https://reactome.org/PathwayBrowser/#/R-HSA-70979 MDH2 dimer dehydrogenates MAL TAS Homo sapiens 16452 R-HSA-75848 https://reactome.org/PathwayBrowser/#/R-HSA-75848 ACLY tetramer transforms CIT to Ac-CoA TAS Homo sapiens 16452 R-HSA-9012016 https://reactome.org/PathwayBrowser/#/R-HSA-9012016 FAHD1 dimer hydrolyses OA to PYR TAS Homo sapiens 16452 R-HSA-9854315 https://reactome.org/PathwayBrowser/#/R-HSA-9854315 CSKMT methylates Citrate Synthase TAS Homo sapiens 16452 R-HSA-9856871 https://reactome.org/PathwayBrowser/#/R-HSA-9856871 MDH1 reduces OA TAS Homo sapiens 16452 R-HSA-9861660 https://reactome.org/PathwayBrowser/#/R-HSA-9861660 ME1 tetramer decarboxylates OA to PYR TAS Homo sapiens 16452 R-MMU-372819 https://reactome.org/PathwayBrowser/#/R-MMU-372819 PCK2 phosphorylates OA to yield PEP IEA Mus musculus 16452 R-MMU-6784393 https://reactome.org/PathwayBrowser/#/R-MMU-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Mus musculus 16452 R-MMU-6810076 https://reactome.org/PathwayBrowser/#/R-MMU-6810076 DDO oxidizes D-Asp to OA IEA Mus musculus 16452 R-MMU-70241 https://reactome.org/PathwayBrowser/#/R-MMU-70241 PCK1 phosphorylates OA to yield PEP IEA Mus musculus 16452 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 16452 R-MMU-70581 https://reactome.org/PathwayBrowser/#/R-MMU-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Mus musculus 16452 R-MMU-70592 https://reactome.org/PathwayBrowser/#/R-MMU-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Mus musculus 16452 R-MMU-70596 https://reactome.org/PathwayBrowser/#/R-MMU-70596 GOT2 dimer deaminates L-Asp IEA Mus musculus 16452 R-MMU-70613 https://reactome.org/PathwayBrowser/#/R-MMU-70613 GOT2 transaminates OA and L-Glu IEA Mus musculus 16452 R-MMU-70975 https://reactome.org/PathwayBrowser/#/R-MMU-70975 CS acetylates OA to citrate IEA Mus musculus 16452 R-MMU-70979 https://reactome.org/PathwayBrowser/#/R-MMU-70979 MDH2 dimer dehydrogenates MAL IEA Mus musculus 16452 R-MMU-75848 https://reactome.org/PathwayBrowser/#/R-MMU-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Mus musculus 16452 R-MMU-9012016 https://reactome.org/PathwayBrowser/#/R-MMU-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Mus musculus 16452 R-MMU-9856871 https://reactome.org/PathwayBrowser/#/R-MMU-9856871 MDH1 reduces OA IEA Mus musculus 16452 R-MMU-9861660 https://reactome.org/PathwayBrowser/#/R-MMU-9861660 ME1 tetramer decarboxylates OA to PYR IEA Mus musculus 16452 R-PFA-70581 https://reactome.org/PathwayBrowser/#/R-PFA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Plasmodium falciparum 16452 R-PFA-70592 https://reactome.org/PathwayBrowser/#/R-PFA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Plasmodium falciparum 16452 R-PFA-70975 https://reactome.org/PathwayBrowser/#/R-PFA-70975 CS acetylates OA to citrate IEA Plasmodium falciparum 16452 R-PFA-70979 https://reactome.org/PathwayBrowser/#/R-PFA-70979 MDH2 dimer dehydrogenates MAL IEA Plasmodium falciparum 16452 R-RNO-372819 https://reactome.org/PathwayBrowser/#/R-RNO-372819 PCK2 phosphorylates OA to yield PEP IEA Rattus norvegicus 16452 R-RNO-6784393 https://reactome.org/PathwayBrowser/#/R-RNO-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Rattus norvegicus 16452 R-RNO-6810076 https://reactome.org/PathwayBrowser/#/R-RNO-6810076 DDO oxidizes D-Asp to OA IEA Rattus norvegicus 16452 R-RNO-70241 https://reactome.org/PathwayBrowser/#/R-RNO-70241 PCK1 phosphorylates OA to yield PEP IEA Rattus norvegicus 16452 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 16452 R-RNO-70581 https://reactome.org/PathwayBrowser/#/R-RNO-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Rattus norvegicus 16452 R-RNO-70592 https://reactome.org/PathwayBrowser/#/R-RNO-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Rattus norvegicus 16452 R-RNO-70596 https://reactome.org/PathwayBrowser/#/R-RNO-70596 GOT2 dimer deaminates L-Asp IEA Rattus norvegicus 16452 R-RNO-70613 https://reactome.org/PathwayBrowser/#/R-RNO-70613 GOT2 transaminates OA and L-Glu IEA Rattus norvegicus 16452 R-RNO-70975 https://reactome.org/PathwayBrowser/#/R-RNO-70975 CS acetylates OA to citrate IEA Rattus norvegicus 16452 R-RNO-70979 https://reactome.org/PathwayBrowser/#/R-RNO-70979 MDH2 dimer dehydrogenates MAL IEA Rattus norvegicus 16452 R-RNO-75848 https://reactome.org/PathwayBrowser/#/R-RNO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Rattus norvegicus 16452 R-RNO-9012016 https://reactome.org/PathwayBrowser/#/R-RNO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Rattus norvegicus 16452 R-RNO-9856871 https://reactome.org/PathwayBrowser/#/R-RNO-9856871 MDH1 reduces OA IEA Rattus norvegicus 16452 R-RNO-9861660 https://reactome.org/PathwayBrowser/#/R-RNO-9861660 ME1 tetramer decarboxylates OA to PYR IEA Rattus norvegicus 16452 R-SCE-6784393 https://reactome.org/PathwayBrowser/#/R-SCE-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Saccharomyces cerevisiae 16452 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 16452 R-SCE-70581 https://reactome.org/PathwayBrowser/#/R-SCE-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Saccharomyces cerevisiae 16452 R-SCE-70592 https://reactome.org/PathwayBrowser/#/R-SCE-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Saccharomyces cerevisiae 16452 R-SCE-70596 https://reactome.org/PathwayBrowser/#/R-SCE-70596 GOT2 dimer deaminates L-Asp IEA Saccharomyces cerevisiae 16452 R-SCE-70613 https://reactome.org/PathwayBrowser/#/R-SCE-70613 GOT2 transaminates OA and L-Glu IEA Saccharomyces cerevisiae 16452 R-SCE-70975 https://reactome.org/PathwayBrowser/#/R-SCE-70975 CS acetylates OA to citrate IEA Saccharomyces cerevisiae 16452 R-SCE-70979 https://reactome.org/PathwayBrowser/#/R-SCE-70979 MDH2 dimer dehydrogenates MAL IEA Saccharomyces cerevisiae 16452 R-SCE-9012016 https://reactome.org/PathwayBrowser/#/R-SCE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Saccharomyces cerevisiae 16452 R-SPO-6784393 https://reactome.org/PathwayBrowser/#/R-SPO-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Schizosaccharomyces pombe 16452 R-SPO-6810076 https://reactome.org/PathwayBrowser/#/R-SPO-6810076 DDO oxidizes D-Asp to OA IEA Schizosaccharomyces pombe 16452 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 16452 R-SPO-70581 https://reactome.org/PathwayBrowser/#/R-SPO-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Schizosaccharomyces pombe 16452 R-SPO-70592 https://reactome.org/PathwayBrowser/#/R-SPO-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Schizosaccharomyces pombe 16452 R-SPO-70596 https://reactome.org/PathwayBrowser/#/R-SPO-70596 GOT2 dimer deaminates L-Asp IEA Schizosaccharomyces pombe 16452 R-SPO-70613 https://reactome.org/PathwayBrowser/#/R-SPO-70613 GOT2 transaminates OA and L-Glu IEA Schizosaccharomyces pombe 16452 R-SPO-70975 https://reactome.org/PathwayBrowser/#/R-SPO-70975 CS acetylates OA to citrate IEA Schizosaccharomyces pombe 16452 R-SPO-70979 https://reactome.org/PathwayBrowser/#/R-SPO-70979 MDH2 dimer dehydrogenates MAL IEA Schizosaccharomyces pombe 16452 R-SPO-75848 https://reactome.org/PathwayBrowser/#/R-SPO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Schizosaccharomyces pombe 16452 R-SPO-9012016 https://reactome.org/PathwayBrowser/#/R-SPO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Schizosaccharomyces pombe 16452 R-SSC-372819 https://reactome.org/PathwayBrowser/#/R-SSC-372819 PCK2 phosphorylates OA to yield PEP IEA Sus scrofa 16452 R-SSC-6784393 https://reactome.org/PathwayBrowser/#/R-SSC-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Sus scrofa 16452 R-SSC-6810076 https://reactome.org/PathwayBrowser/#/R-SSC-6810076 DDO oxidizes D-Asp to OA IEA Sus scrofa 16452 R-SSC-70241 https://reactome.org/PathwayBrowser/#/R-SSC-70241 PCK1 phosphorylates OA to yield PEP IEA Sus scrofa 16452 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 16452 R-SSC-70581 https://reactome.org/PathwayBrowser/#/R-SSC-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Sus scrofa 16452 R-SSC-70592 https://reactome.org/PathwayBrowser/#/R-SSC-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Sus scrofa 16452 R-SSC-70596 https://reactome.org/PathwayBrowser/#/R-SSC-70596 GOT2 dimer deaminates L-Asp IEA Sus scrofa 16452 R-SSC-70613 https://reactome.org/PathwayBrowser/#/R-SSC-70613 GOT2 transaminates OA and L-Glu IEA Sus scrofa 16452 R-SSC-70975 https://reactome.org/PathwayBrowser/#/R-SSC-70975 CS acetylates OA to citrate IEA Sus scrofa 16452 R-SSC-70979 https://reactome.org/PathwayBrowser/#/R-SSC-70979 MDH2 dimer dehydrogenates MAL IEA Sus scrofa 16452 R-SSC-75848 https://reactome.org/PathwayBrowser/#/R-SSC-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Sus scrofa 16452 R-SSC-9012016 https://reactome.org/PathwayBrowser/#/R-SSC-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Sus scrofa 16452 R-SSC-9854315 https://reactome.org/PathwayBrowser/#/R-SSC-9854315 CSKMT methylates Citrate Synthase IEA Sus scrofa 16452 R-SSC-9856871 https://reactome.org/PathwayBrowser/#/R-SSC-9856871 MDH1 reduces OA IEA Sus scrofa 16452 R-SSC-9861660 https://reactome.org/PathwayBrowser/#/R-SSC-9861660 ME1 tetramer decarboxylates OA to PYR IEA Sus scrofa 16452 R-XTR-6784393 https://reactome.org/PathwayBrowser/#/R-XTR-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Xenopus tropicalis 16452 R-XTR-70241 https://reactome.org/PathwayBrowser/#/R-XTR-70241 PCK1 phosphorylates OA to yield PEP IEA Xenopus tropicalis 16452 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 16452 R-XTR-70581 https://reactome.org/PathwayBrowser/#/R-XTR-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Xenopus tropicalis 16452 R-XTR-70592 https://reactome.org/PathwayBrowser/#/R-XTR-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Xenopus tropicalis 16452 R-XTR-70596 https://reactome.org/PathwayBrowser/#/R-XTR-70596 GOT2 dimer deaminates L-Asp IEA Xenopus tropicalis 16452 R-XTR-70613 https://reactome.org/PathwayBrowser/#/R-XTR-70613 GOT2 transaminates OA and L-Glu IEA Xenopus tropicalis 16452 R-XTR-70975 https://reactome.org/PathwayBrowser/#/R-XTR-70975 CS acetylates OA to citrate IEA Xenopus tropicalis 16452 R-XTR-70979 https://reactome.org/PathwayBrowser/#/R-XTR-70979 MDH2 dimer dehydrogenates MAL IEA Xenopus tropicalis 16452 R-XTR-75848 https://reactome.org/PathwayBrowser/#/R-XTR-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Xenopus tropicalis 16452 R-XTR-9012016 https://reactome.org/PathwayBrowser/#/R-XTR-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Xenopus tropicalis 16452 R-XTR-9856871 https://reactome.org/PathwayBrowser/#/R-XTR-9856871 MDH1 reduces OA IEA Xenopus tropicalis 16466 R-BTA-192042 https://reactome.org/PathwayBrowser/#/R-BTA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 16466 R-BTA-192054 https://reactome.org/PathwayBrowser/#/R-BTA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Bos taurus 16466 R-CFA-192042 https://reactome.org/PathwayBrowser/#/R-CFA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 16466 R-CFA-192054 https://reactome.org/PathwayBrowser/#/R-CFA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Canis familiaris 16466 R-HSA-192042 https://reactome.org/PathwayBrowser/#/R-HSA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 16466 R-HSA-192054 https://reactome.org/PathwayBrowser/#/R-HSA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) TAS Homo sapiens 16466 R-MMU-192042 https://reactome.org/PathwayBrowser/#/R-MMU-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 16466 R-MMU-192054 https://reactome.org/PathwayBrowser/#/R-MMU-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Mus musculus 16466 R-RNO-192042 https://reactome.org/PathwayBrowser/#/R-RNO-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 16466 R-RNO-192054 https://reactome.org/PathwayBrowser/#/R-RNO-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Rattus norvegicus 16466 R-SSC-192042 https://reactome.org/PathwayBrowser/#/R-SSC-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 16466 R-SSC-192054 https://reactome.org/PathwayBrowser/#/R-SSC-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Sus scrofa 16469 R-BTA-176521 https://reactome.org/PathwayBrowser/#/R-BTA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Bos taurus 16469 R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 16469 R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 16469 R-BTA-5693390 https://reactome.org/PathwayBrowser/#/R-BTA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Bos taurus 16469 R-BTA-5696822 https://reactome.org/PathwayBrowser/#/R-BTA-5696822 AKR1B15 reduces EST17b to E1 IEA Bos taurus 16469 R-BTA-6810594 https://reactome.org/PathwayBrowser/#/R-BTA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 16469 R-BTA-804969 https://reactome.org/PathwayBrowser/#/R-BTA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Bos taurus 16469 R-BTA-8862137 https://reactome.org/PathwayBrowser/#/R-BTA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 16469 R-BTA-9008258 https://reactome.org/PathwayBrowser/#/R-BTA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Bos taurus 16469 R-BTA-9008270 https://reactome.org/PathwayBrowser/#/R-BTA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Bos taurus 16469 R-BTA-9008271 https://reactome.org/PathwayBrowser/#/R-BTA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Bos taurus 16469 R-BTA-9008285 https://reactome.org/PathwayBrowser/#/R-BTA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Bos taurus 16469 R-BTA-9009526 https://reactome.org/PathwayBrowser/#/R-BTA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 16469 R-BTA-9009533 https://reactome.org/PathwayBrowser/#/R-BTA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Bos taurus 16469 R-BTA-9009536 https://reactome.org/PathwayBrowser/#/R-BTA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Bos taurus 16469 R-BTA-9009541 https://reactome.org/PathwayBrowser/#/R-BTA-9009541 ESR1 binds to TFF1 gene promoter IEA Bos taurus 16469 R-BTA-9023860 https://reactome.org/PathwayBrowser/#/R-BTA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Bos taurus 16469 R-BTA-9023861 https://reactome.org/PathwayBrowser/#/R-BTA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 16469 R-BTA-9023884 https://reactome.org/PathwayBrowser/#/R-BTA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Bos taurus 16469 R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 16469 R-CEL-5696822 https://reactome.org/PathwayBrowser/#/R-CEL-5696822 AKR1B15 reduces EST17b to E1 IEA Caenorhabditis elegans 16469 R-CFA-176521 https://reactome.org/PathwayBrowser/#/R-CFA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Canis familiaris 16469 R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 16469 R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 16469 R-CFA-5693390 https://reactome.org/PathwayBrowser/#/R-CFA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Canis familiaris 16469 R-CFA-804969 https://reactome.org/PathwayBrowser/#/R-CFA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Canis familiaris 16469 R-CFA-8862137 https://reactome.org/PathwayBrowser/#/R-CFA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Canis familiaris 16469 R-CFA-9008258 https://reactome.org/PathwayBrowser/#/R-CFA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Canis familiaris 16469 R-CFA-9008270 https://reactome.org/PathwayBrowser/#/R-CFA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Canis familiaris 16469 R-CFA-9008271 https://reactome.org/PathwayBrowser/#/R-CFA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Canis familiaris 16469 R-CFA-9008285 https://reactome.org/PathwayBrowser/#/R-CFA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Canis familiaris 16469 R-CFA-9009526 https://reactome.org/PathwayBrowser/#/R-CFA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 16469 R-CFA-9009533 https://reactome.org/PathwayBrowser/#/R-CFA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Canis familiaris 16469 R-CFA-9009536 https://reactome.org/PathwayBrowser/#/R-CFA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Canis familiaris 16469 R-CFA-9009541 https://reactome.org/PathwayBrowser/#/R-CFA-9009541 ESR1 binds to TFF1 gene promoter IEA Canis familiaris 16469 R-CFA-9023860 https://reactome.org/PathwayBrowser/#/R-CFA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Canis familiaris 16469 R-CFA-9023861 https://reactome.org/PathwayBrowser/#/R-CFA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 16469 R-CFA-9023884 https://reactome.org/PathwayBrowser/#/R-CFA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Canis familiaris 16469 R-DDI-5696822 https://reactome.org/PathwayBrowser/#/R-DDI-5696822 AKR1B15 reduces EST17b to E1 IEA Dictyostelium discoideum 16469 R-DDI-804969 https://reactome.org/PathwayBrowser/#/R-DDI-804969 HSD17B1 hydrogenates E1 to EST17b IEA Dictyostelium discoideum 16469 R-DDI-9023860 https://reactome.org/PathwayBrowser/#/R-DDI-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Dictyostelium discoideum 16469 R-DME-176521 https://reactome.org/PathwayBrowser/#/R-DME-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Drosophila melanogaster 16469 R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 16469 R-DME-5693390 https://reactome.org/PathwayBrowser/#/R-DME-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Drosophila melanogaster 16469 R-DME-5696822 https://reactome.org/PathwayBrowser/#/R-DME-5696822 AKR1B15 reduces EST17b to E1 IEA Drosophila melanogaster 16469 R-DME-8862137 https://reactome.org/PathwayBrowser/#/R-DME-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Drosophila melanogaster 16469 R-DME-9008258 https://reactome.org/PathwayBrowser/#/R-DME-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Drosophila melanogaster 16469 R-DME-9008270 https://reactome.org/PathwayBrowser/#/R-DME-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Drosophila melanogaster 16469 R-DME-9008285 https://reactome.org/PathwayBrowser/#/R-DME-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Drosophila melanogaster 16469 R-DME-9009526 https://reactome.org/PathwayBrowser/#/R-DME-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 16469 R-DME-9009533 https://reactome.org/PathwayBrowser/#/R-DME-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Drosophila melanogaster 16469 R-DME-9009536 https://reactome.org/PathwayBrowser/#/R-DME-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Drosophila melanogaster 16469 R-DME-9009541 https://reactome.org/PathwayBrowser/#/R-DME-9009541 ESR1 binds to TFF1 gene promoter IEA Drosophila melanogaster 16469 R-DME-9023860 https://reactome.org/PathwayBrowser/#/R-DME-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Drosophila melanogaster 16469 R-DME-9023861 https://reactome.org/PathwayBrowser/#/R-DME-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 16469 R-DME-9023884 https://reactome.org/PathwayBrowser/#/R-DME-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Drosophila melanogaster 16469 R-DRE-176521 https://reactome.org/PathwayBrowser/#/R-DRE-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Danio rerio 16469 R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 16469 R-DRE-211951 https://reactome.org/PathwayBrowser/#/R-DRE-211951 CYP1B1 4-hydroxylates EST17b IEA Danio rerio 16469 R-DRE-5696822 https://reactome.org/PathwayBrowser/#/R-DRE-5696822 AKR1B15 reduces EST17b to E1 IEA Danio rerio 16469 R-DRE-6810594 https://reactome.org/PathwayBrowser/#/R-DRE-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Danio rerio 16469 R-DRE-9009526 https://reactome.org/PathwayBrowser/#/R-DRE-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Danio rerio 16469 R-DRE-9009533 https://reactome.org/PathwayBrowser/#/R-DRE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Danio rerio 16469 R-DRE-9009541 https://reactome.org/PathwayBrowser/#/R-DRE-9009541 ESR1 binds to TFF1 gene promoter IEA Danio rerio 16469 R-DRE-9023860 https://reactome.org/PathwayBrowser/#/R-DRE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Danio rerio 16469 R-GGA-176521 https://reactome.org/PathwayBrowser/#/R-GGA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Gallus gallus 16469 R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 16469 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 16469 R-GGA-5693390 https://reactome.org/PathwayBrowser/#/R-GGA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Gallus gallus 16469 R-GGA-5696822 https://reactome.org/PathwayBrowser/#/R-GGA-5696822 AKR1B15 reduces EST17b to E1 IEA Gallus gallus 16469 R-GGA-8862137 https://reactome.org/PathwayBrowser/#/R-GGA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Gallus gallus 16469 R-GGA-9008258 https://reactome.org/PathwayBrowser/#/R-GGA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Gallus gallus 16469 R-GGA-9008270 https://reactome.org/PathwayBrowser/#/R-GGA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Gallus gallus 16469 R-GGA-9008285 https://reactome.org/PathwayBrowser/#/R-GGA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Gallus gallus 16469 R-GGA-9009533 https://reactome.org/PathwayBrowser/#/R-GGA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Gallus gallus 16469 R-GGA-9009536 https://reactome.org/PathwayBrowser/#/R-GGA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Gallus gallus 16469 R-GGA-9009541 https://reactome.org/PathwayBrowser/#/R-GGA-9009541 ESR1 binds to TFF1 gene promoter IEA Gallus gallus 16469 R-GGA-9023860 https://reactome.org/PathwayBrowser/#/R-GGA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Gallus gallus 16469 R-GGA-9023884 https://reactome.org/PathwayBrowser/#/R-GGA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Gallus gallus 16469 R-HSA-176521 https://reactome.org/PathwayBrowser/#/R-HSA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP TAS Homo sapiens 16469 R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 16469 R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 16469 R-HSA-5605147 https://reactome.org/PathwayBrowser/#/R-HSA-5605147 Defective CYP1B1 does not 4-hydroxylate EST17b TAS Homo sapiens 16469 R-HSA-5693390 https://reactome.org/PathwayBrowser/#/R-HSA-5693390 HSD17B11 dehydrogenates EST17b to E1 TAS Homo sapiens 16469 R-HSA-5696822 https://reactome.org/PathwayBrowser/#/R-HSA-5696822 AKR1B15 reduces EST17b to E1 TAS Homo sapiens 16469 R-HSA-6810594 https://reactome.org/PathwayBrowser/#/R-HSA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 16469 R-HSA-804969 https://reactome.org/PathwayBrowser/#/R-HSA-804969 HSD17B1 hydrogenates E1 to EST17b TAS Homo sapiens 16469 R-HSA-8862137 https://reactome.org/PathwayBrowser/#/R-HSA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 16469 R-HSA-9008258 https://reactome.org/PathwayBrowser/#/R-HSA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene TAS Homo sapiens 16469 R-HSA-9008267 https://reactome.org/PathwayBrowser/#/R-HSA-9008267 ESR1 binds to TGFA gene promoter TAS Homo sapiens 16469 R-HSA-9008270 https://reactome.org/PathwayBrowser/#/R-HSA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene TAS Homo sapiens 16469 R-HSA-9008271 https://reactome.org/PathwayBrowser/#/R-HSA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter TAS Homo sapiens 16469 R-HSA-9008285 https://reactome.org/PathwayBrowser/#/R-HSA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 TAS Homo sapiens 16469 R-HSA-9008315 https://reactome.org/PathwayBrowser/#/R-HSA-9008315 TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen TAS Homo sapiens 16469 R-HSA-9009526 https://reactome.org/PathwayBrowser/#/R-HSA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 16469 R-HSA-9009533 https://reactome.org/PathwayBrowser/#/R-HSA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter TAS Homo sapiens 16469 R-HSA-9009536 https://reactome.org/PathwayBrowser/#/R-HSA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter TAS Homo sapiens 16469 R-HSA-9009541 https://reactome.org/PathwayBrowser/#/R-HSA-9009541 ESR1 binds to TFF1 gene promoter TAS Homo sapiens 16469 R-HSA-9023859 https://reactome.org/PathwayBrowser/#/R-HSA-9023859 Estrogen-responsive TFF1 gene expression TAS Homo sapiens 16469 R-HSA-9023860 https://reactome.org/PathwayBrowser/#/R-HSA-9023860 Histone acetyltransferases are recruited to the TFF1 gene TAS Homo sapiens 16469 R-HSA-9023861 https://reactome.org/PathwayBrowser/#/R-HSA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 16469 R-HSA-9023884 https://reactome.org/PathwayBrowser/#/R-HSA-9023884 NCOA1 recruits EP300 to TGFA promoter TAS Homo sapiens 16469 R-MMU-176521 https://reactome.org/PathwayBrowser/#/R-MMU-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Mus musculus 16469 R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 16469 R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 16469 R-MMU-5693390 https://reactome.org/PathwayBrowser/#/R-MMU-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Mus musculus 16469 R-MMU-5696822 https://reactome.org/PathwayBrowser/#/R-MMU-5696822 AKR1B15 reduces EST17b to E1 IEA Mus musculus 16469 R-MMU-6810594 https://reactome.org/PathwayBrowser/#/R-MMU-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 16469 R-MMU-804969 https://reactome.org/PathwayBrowser/#/R-MMU-804969 HSD17B1 hydrogenates E1 to EST17b IEA Mus musculus 16469 R-MMU-8862137 https://reactome.org/PathwayBrowser/#/R-MMU-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 16469 R-MMU-9008258 https://reactome.org/PathwayBrowser/#/R-MMU-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Mus musculus 16469 R-MMU-9008270 https://reactome.org/PathwayBrowser/#/R-MMU-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Mus musculus 16469 R-MMU-9008271 https://reactome.org/PathwayBrowser/#/R-MMU-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Mus musculus 16469 R-MMU-9008285 https://reactome.org/PathwayBrowser/#/R-MMU-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Mus musculus 16469 R-MMU-9009526 https://reactome.org/PathwayBrowser/#/R-MMU-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 16469 R-MMU-9009533 https://reactome.org/PathwayBrowser/#/R-MMU-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Mus musculus 16469 R-MMU-9009536 https://reactome.org/PathwayBrowser/#/R-MMU-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Mus musculus 16469 R-MMU-9009541 https://reactome.org/PathwayBrowser/#/R-MMU-9009541 ESR1 binds to TFF1 gene promoter IEA Mus musculus 16469 R-MMU-9023860 https://reactome.org/PathwayBrowser/#/R-MMU-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Mus musculus 16469 R-MMU-9023861 https://reactome.org/PathwayBrowser/#/R-MMU-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 16469 R-MMU-9023884 https://reactome.org/PathwayBrowser/#/R-MMU-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Mus musculus 16469 R-RNO-176521 https://reactome.org/PathwayBrowser/#/R-RNO-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Rattus norvegicus 16469 R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 16469 R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 16469 R-RNO-5693390 https://reactome.org/PathwayBrowser/#/R-RNO-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Rattus norvegicus 16469 R-RNO-5696822 https://reactome.org/PathwayBrowser/#/R-RNO-5696822 AKR1B15 reduces EST17b to E1 IEA Rattus norvegicus 16469 R-RNO-6810594 https://reactome.org/PathwayBrowser/#/R-RNO-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 16469 R-RNO-804969 https://reactome.org/PathwayBrowser/#/R-RNO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Rattus norvegicus 16469 R-RNO-8862137 https://reactome.org/PathwayBrowser/#/R-RNO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 16469 R-RNO-9008258 https://reactome.org/PathwayBrowser/#/R-RNO-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Rattus norvegicus 16469 R-RNO-9008270 https://reactome.org/PathwayBrowser/#/R-RNO-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Rattus norvegicus 16469 R-RNO-9008271 https://reactome.org/PathwayBrowser/#/R-RNO-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Rattus norvegicus 16469 R-RNO-9008285 https://reactome.org/PathwayBrowser/#/R-RNO-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Rattus norvegicus 16469 R-RNO-9009526 https://reactome.org/PathwayBrowser/#/R-RNO-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 16469 R-RNO-9009533 https://reactome.org/PathwayBrowser/#/R-RNO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Rattus norvegicus 16469 R-RNO-9009536 https://reactome.org/PathwayBrowser/#/R-RNO-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Rattus norvegicus 16469 R-RNO-9009541 https://reactome.org/PathwayBrowser/#/R-RNO-9009541 ESR1 binds to TFF1 gene promoter IEA Rattus norvegicus 16469 R-RNO-9023860 https://reactome.org/PathwayBrowser/#/R-RNO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Rattus norvegicus 16469 R-RNO-9023861 https://reactome.org/PathwayBrowser/#/R-RNO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 16469 R-RNO-9023884 https://reactome.org/PathwayBrowser/#/R-RNO-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Rattus norvegicus 16469 R-SCE-5693390 https://reactome.org/PathwayBrowser/#/R-SCE-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Saccharomyces cerevisiae 16469 R-SCE-5696822 https://reactome.org/PathwayBrowser/#/R-SCE-5696822 AKR1B15 reduces EST17b to E1 IEA Saccharomyces cerevisiae 16469 R-SCE-9009533 https://reactome.org/PathwayBrowser/#/R-SCE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Saccharomyces cerevisiae 16469 R-SCE-9023860 https://reactome.org/PathwayBrowser/#/R-SCE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Saccharomyces cerevisiae 16469 R-SCE-9023861 https://reactome.org/PathwayBrowser/#/R-SCE-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Saccharomyces cerevisiae 16469 R-SPO-5696822 https://reactome.org/PathwayBrowser/#/R-SPO-5696822 AKR1B15 reduces EST17b to E1 IEA Schizosaccharomyces pombe 16469 R-SPO-804969 https://reactome.org/PathwayBrowser/#/R-SPO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Schizosaccharomyces pombe 16469 R-SPO-8862137 https://reactome.org/PathwayBrowser/#/R-SPO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Schizosaccharomyces pombe 16469 R-SPO-9009533 https://reactome.org/PathwayBrowser/#/R-SPO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Schizosaccharomyces pombe 16469 R-SPO-9023860 https://reactome.org/PathwayBrowser/#/R-SPO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Schizosaccharomyces pombe 16469 R-SPO-9023861 https://reactome.org/PathwayBrowser/#/R-SPO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Schizosaccharomyces pombe 16469 R-SSC-176521 https://reactome.org/PathwayBrowser/#/R-SSC-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Sus scrofa 16469 R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 16469 R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 16469 R-SSC-5693390 https://reactome.org/PathwayBrowser/#/R-SSC-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Sus scrofa 16469 R-SSC-804969 https://reactome.org/PathwayBrowser/#/R-SSC-804969 HSD17B1 hydrogenates E1 to EST17b IEA Sus scrofa 16469 R-SSC-8862137 https://reactome.org/PathwayBrowser/#/R-SSC-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Sus scrofa 16469 R-SSC-9008258 https://reactome.org/PathwayBrowser/#/R-SSC-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Sus scrofa 16469 R-SSC-9008270 https://reactome.org/PathwayBrowser/#/R-SSC-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Sus scrofa 16469 R-SSC-9008271 https://reactome.org/PathwayBrowser/#/R-SSC-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Sus scrofa 16469 R-SSC-9008285 https://reactome.org/PathwayBrowser/#/R-SSC-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Sus scrofa 16469 R-SSC-9009526 https://reactome.org/PathwayBrowser/#/R-SSC-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 16469 R-SSC-9009536 https://reactome.org/PathwayBrowser/#/R-SSC-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Sus scrofa 16469 R-SSC-9009541 https://reactome.org/PathwayBrowser/#/R-SSC-9009541 ESR1 binds to TFF1 gene promoter IEA Sus scrofa 16469 R-SSC-9023860 https://reactome.org/PathwayBrowser/#/R-SSC-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Sus scrofa 16469 R-SSC-9023861 https://reactome.org/PathwayBrowser/#/R-SSC-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 16469 R-SSC-9023884 https://reactome.org/PathwayBrowser/#/R-SSC-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Sus scrofa 16469 R-XTR-176521 https://reactome.org/PathwayBrowser/#/R-XTR-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Xenopus tropicalis 16469 R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 16469 R-XTR-5693390 https://reactome.org/PathwayBrowser/#/R-XTR-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Xenopus tropicalis 16469 R-XTR-5696822 https://reactome.org/PathwayBrowser/#/R-XTR-5696822 AKR1B15 reduces EST17b to E1 IEA Xenopus tropicalis 16469 R-XTR-6810594 https://reactome.org/PathwayBrowser/#/R-XTR-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 16469 R-XTR-804969 https://reactome.org/PathwayBrowser/#/R-XTR-804969 HSD17B1 hydrogenates E1 to EST17b IEA Xenopus tropicalis 16469 R-XTR-8862137 https://reactome.org/PathwayBrowser/#/R-XTR-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 16469 R-XTR-9008258 https://reactome.org/PathwayBrowser/#/R-XTR-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Xenopus tropicalis 16469 R-XTR-9008285 https://reactome.org/PathwayBrowser/#/R-XTR-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Xenopus tropicalis 16469 R-XTR-9023860 https://reactome.org/PathwayBrowser/#/R-XTR-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Xenopus tropicalis 16474 R-BTA-1236967 https://reactome.org/PathwayBrowser/#/R-BTA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Bos taurus 16474 R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 16474 R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 16474 R-BTA-194674 https://reactome.org/PathwayBrowser/#/R-BTA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Bos taurus 16474 R-BTA-2046083 https://reactome.org/PathwayBrowser/#/R-BTA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Bos taurus 16474 R-BTA-2046088 https://reactome.org/PathwayBrowser/#/R-BTA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Bos taurus 16474 R-BTA-2046090 https://reactome.org/PathwayBrowser/#/R-BTA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 16474 R-BTA-2046094 https://reactome.org/PathwayBrowser/#/R-BTA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Bos taurus 16474 R-BTA-2046095 https://reactome.org/PathwayBrowser/#/R-BTA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Bos taurus 16474 R-BTA-2046100 https://reactome.org/PathwayBrowser/#/R-BTA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Bos taurus 16474 R-BTA-209921 https://reactome.org/PathwayBrowser/#/R-BTA-209921 Monoiodinated tyrosine can be deiodinated IEA Bos taurus 16474 R-BTA-209960 https://reactome.org/PathwayBrowser/#/R-BTA-209960 Diiodinated tyrosine can be deiodinated IEA Bos taurus 16474 R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 16474 R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 16474 R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 16474 R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 16474 R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 16474 R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 16474 R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 16474 R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 16474 R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 16474 R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 16474 R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 16474 R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 16474 R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 16474 R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 16474 R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 16474 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 16474 R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 16474 R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 16474 R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 16474 R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 16474 R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 16474 R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 16474 R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Bos taurus 16474 R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 16474 R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 16474 R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 16474 R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 16474 R-BTA-350901 https://reactome.org/PathwayBrowser/#/R-BTA-350901 Iodide is organified IEA Bos taurus 16474 R-BTA-389550 https://reactome.org/PathwayBrowser/#/R-BTA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 16474 R-BTA-389826 https://reactome.org/PathwayBrowser/#/R-BTA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Bos taurus 16474 R-BTA-5623643 https://reactome.org/PathwayBrowser/#/R-BTA-5623643 RDH13 reduces atRAL to atROL IEA Bos taurus 16474 R-BTA-5693347 https://reactome.org/PathwayBrowser/#/R-BTA-5693347 CRYM reduces P2C to PPCA IEA Bos taurus 16474 R-BTA-5693681 https://reactome.org/PathwayBrowser/#/R-BTA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Bos taurus 16474 R-BTA-6786720 https://reactome.org/PathwayBrowser/#/R-BTA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Bos taurus 16474 R-BTA-6809810 https://reactome.org/PathwayBrowser/#/R-BTA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Bos taurus 16474 R-BTA-76031 https://reactome.org/PathwayBrowser/#/R-BTA-76031 2 H2O2 => O2 + 2 H2O IEA Bos taurus 16474 R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 16474 R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 16474 R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 16474 R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 16474 R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 16474 R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 16474 R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 16474 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 16474 R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 16474 R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 16474 R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 16474 R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 16474 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 16474 R-CEL-2046088 https://reactome.org/PathwayBrowser/#/R-CEL-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Caenorhabditis elegans 16474 R-CEL-2046094 https://reactome.org/PathwayBrowser/#/R-CEL-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Caenorhabditis elegans 16474 R-CEL-209921 https://reactome.org/PathwayBrowser/#/R-CEL-209921 Monoiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 16474 R-CEL-209960 https://reactome.org/PathwayBrowser/#/R-CEL-209960 Diiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 16474 R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 16474 R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 16474 R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 16474 R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 16474 R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 16474 R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 16474 R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 16474 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 16474 R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 16474 R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 16474 R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 16474 R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 16474 R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 16474 R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 16474 R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 16474 R-CEL-350901 https://reactome.org/PathwayBrowser/#/R-CEL-350901 Iodide is organified IEA Caenorhabditis elegans 16474 R-CEL-389550 https://reactome.org/PathwayBrowser/#/R-CEL-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 16474 R-CEL-5623643 https://reactome.org/PathwayBrowser/#/R-CEL-5623643 RDH13 reduces atRAL to atROL IEA Caenorhabditis elegans 16474 R-CEL-5693681 https://reactome.org/PathwayBrowser/#/R-CEL-5693681 DUOX1,2 reduce O2 to H2O2 IEA Caenorhabditis elegans 16474 R-CEL-76031 https://reactome.org/PathwayBrowser/#/R-CEL-76031 2 H2O2 => O2 + 2 H2O IEA Caenorhabditis elegans 16474 R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 16474 R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 16474 R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 16474 R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 16474 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 16474 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 16474 R-CFA-1236967 https://reactome.org/PathwayBrowser/#/R-CFA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Canis familiaris 16474 R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 16474 R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 16474 R-CFA-194674 https://reactome.org/PathwayBrowser/#/R-CFA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Canis familiaris 16474 R-CFA-2046083 https://reactome.org/PathwayBrowser/#/R-CFA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Canis familiaris 16474 R-CFA-2046088 https://reactome.org/PathwayBrowser/#/R-CFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Canis familiaris 16474 R-CFA-2046090 https://reactome.org/PathwayBrowser/#/R-CFA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 16474 R-CFA-2046094 https://reactome.org/PathwayBrowser/#/R-CFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Canis familiaris 16474 R-CFA-2046095 https://reactome.org/PathwayBrowser/#/R-CFA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Canis familiaris 16474 R-CFA-2046100 https://reactome.org/PathwayBrowser/#/R-CFA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Canis familiaris 16474 R-CFA-209921 https://reactome.org/PathwayBrowser/#/R-CFA-209921 Monoiodinated tyrosine can be deiodinated IEA Canis familiaris 16474 R-CFA-209960 https://reactome.org/PathwayBrowser/#/R-CFA-209960 Diiodinated tyrosine can be deiodinated IEA Canis familiaris 16474 R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 16474 R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 16474 R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 16474 R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 16474 R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 16474 R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 16474 R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 16474 R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 16474 R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 16474 R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 16474 R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 16474 R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 16474 R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 16474 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 16474 R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 16474 R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 16474 R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 16474 R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 16474 R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Canis familiaris 16474 R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 16474 R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 16474 R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 16474 R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 16474 R-CFA-350901 https://reactome.org/PathwayBrowser/#/R-CFA-350901 Iodide is organified IEA Canis familiaris 16474 R-CFA-389550 https://reactome.org/PathwayBrowser/#/R-CFA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 16474 R-CFA-389826 https://reactome.org/PathwayBrowser/#/R-CFA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Canis familiaris 16474 R-CFA-5623643 https://reactome.org/PathwayBrowser/#/R-CFA-5623643 RDH13 reduces atRAL to atROL IEA Canis familiaris 16474 R-CFA-5693347 https://reactome.org/PathwayBrowser/#/R-CFA-5693347 CRYM reduces P2C to PPCA IEA Canis familiaris 16474 R-CFA-5693681 https://reactome.org/PathwayBrowser/#/R-CFA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Canis familiaris 16474 R-CFA-6786720 https://reactome.org/PathwayBrowser/#/R-CFA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Canis familiaris 16474 R-CFA-6809810 https://reactome.org/PathwayBrowser/#/R-CFA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Canis familiaris 16474 R-CFA-76031 https://reactome.org/PathwayBrowser/#/R-CFA-76031 2 H2O2 => O2 + 2 H2O IEA Canis familiaris 16474 R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 16474 R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 16474 R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 16474 R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 16474 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 16474 R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 16474 R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 16474 R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 16474 R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 16474 R-DDI-194674 https://reactome.org/PathwayBrowser/#/R-DDI-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Dictyostelium discoideum 16474 R-DDI-2046083 https://reactome.org/PathwayBrowser/#/R-DDI-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Dictyostelium discoideum 16474 R-DDI-2046088 https://reactome.org/PathwayBrowser/#/R-DDI-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Dictyostelium discoideum 16474 R-DDI-2046090 https://reactome.org/PathwayBrowser/#/R-DDI-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Dictyostelium discoideum 16474 R-DDI-2046094 https://reactome.org/PathwayBrowser/#/R-DDI-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Dictyostelium discoideum 16474 R-DDI-2046095 https://reactome.org/PathwayBrowser/#/R-DDI-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Dictyostelium discoideum 16474 R-DDI-2046100 https://reactome.org/PathwayBrowser/#/R-DDI-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Dictyostelium discoideum 16474 R-DDI-209973 https://reactome.org/PathwayBrowser/#/R-DDI-209973 Tyrosine is diiodinated IEA Dictyostelium discoideum 16474 R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 16474 R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 16474 R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 16474 R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 16474 R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 16474 R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 16474 R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 16474 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 16474 R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 16474 R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 16474 R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 16474 R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 16474 R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 16474 R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 16474 R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 16474 R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 16474 R-DDI-350901 https://reactome.org/PathwayBrowser/#/R-DDI-350901 Iodide is organified IEA Dictyostelium discoideum 16474 R-DDI-389550 https://reactome.org/PathwayBrowser/#/R-DDI-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 16474 R-DDI-5623643 https://reactome.org/PathwayBrowser/#/R-DDI-5623643 RDH13 reduces atRAL to atROL IEA Dictyostelium discoideum 16474 R-DDI-5693347 https://reactome.org/PathwayBrowser/#/R-DDI-5693347 CRYM reduces P2C to PPCA IEA Dictyostelium discoideum 16474 R-DDI-5693681 https://reactome.org/PathwayBrowser/#/R-DDI-5693681 DUOX1,2 reduce O2 to H2O2 IEA Dictyostelium discoideum 16474 R-DDI-76031 https://reactome.org/PathwayBrowser/#/R-DDI-76031 2 H2O2 => O2 + 2 H2O IEA Dictyostelium discoideum 16474 R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 16474 R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 16474 R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 16474 R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 16474 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 16474 R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 16474 R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 16474 R-DME-2046083 https://reactome.org/PathwayBrowser/#/R-DME-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Drosophila melanogaster 16474 R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster 16474 R-DME-2046090 https://reactome.org/PathwayBrowser/#/R-DME-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Drosophila melanogaster 16474 R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster 16474 R-DME-2046095 https://reactome.org/PathwayBrowser/#/R-DME-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Drosophila melanogaster 16474 R-DME-2046100 https://reactome.org/PathwayBrowser/#/R-DME-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Drosophila melanogaster 16474 R-DME-209921 https://reactome.org/PathwayBrowser/#/R-DME-209921 Monoiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 16474 R-DME-209960 https://reactome.org/PathwayBrowser/#/R-DME-209960 Diiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 16474 R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 16474 R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 16474 R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 16474 R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 16474 R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 16474 R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 16474 R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 16474 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 16474 R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 16474 R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 16474 R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 16474 R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 16474 R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 16474 R-DME-350901 https://reactome.org/PathwayBrowser/#/R-DME-350901 Iodide is organified IEA Drosophila melanogaster 16474 R-DME-389550 https://reactome.org/PathwayBrowser/#/R-DME-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 16474 R-DME-389826 https://reactome.org/PathwayBrowser/#/R-DME-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Drosophila melanogaster 16474 R-DME-5693347 https://reactome.org/PathwayBrowser/#/R-DME-5693347 CRYM reduces P2C to PPCA IEA Drosophila melanogaster 16474 R-DME-5693681 https://reactome.org/PathwayBrowser/#/R-DME-5693681 DUOX1,2 reduce O2 to H2O2 IEA Drosophila melanogaster 16474 R-DME-76031 https://reactome.org/PathwayBrowser/#/R-DME-76031 2 H2O2 => O2 + 2 H2O IEA Drosophila melanogaster 16474 R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 16474 R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 16474 R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 16474 R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 16474 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 16474 R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 16474 R-DRE-1236967 https://reactome.org/PathwayBrowser/#/R-DRE-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Danio rerio 16474 R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 16474 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 16474 R-DRE-194674 https://reactome.org/PathwayBrowser/#/R-DRE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Danio rerio 16474 R-DRE-2046083 https://reactome.org/PathwayBrowser/#/R-DRE-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Danio rerio 16474 R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio 16474 R-DRE-2046090 https://reactome.org/PathwayBrowser/#/R-DRE-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 16474 R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio 16474 R-DRE-2046095 https://reactome.org/PathwayBrowser/#/R-DRE-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Danio rerio 16474 R-DRE-2046100 https://reactome.org/PathwayBrowser/#/R-DRE-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Danio rerio 16474 R-DRE-209921 https://reactome.org/PathwayBrowser/#/R-DRE-209921 Monoiodinated tyrosine can be deiodinated IEA Danio rerio 16474 R-DRE-209960 https://reactome.org/PathwayBrowser/#/R-DRE-209960 Diiodinated tyrosine can be deiodinated IEA Danio rerio 16474 R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 16474 R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 16474 R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 16474 R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 16474 R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 16474 R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 16474 R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 16474 R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 16474 R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 16474 R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 16474 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 16474 R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 16474 R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 16474 R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 16474 R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 16474 R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 16474 R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Danio rerio 16474 R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 16474 R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 16474 R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 16474 R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 16474 R-DRE-389550 https://reactome.org/PathwayBrowser/#/R-DRE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 16474 R-DRE-389826 https://reactome.org/PathwayBrowser/#/R-DRE-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Danio rerio 16474 R-DRE-5693347 https://reactome.org/PathwayBrowser/#/R-DRE-5693347 CRYM reduces P2C to PPCA IEA Danio rerio 16474 R-DRE-6786720 https://reactome.org/PathwayBrowser/#/R-DRE-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Danio rerio 16474 R-DRE-6809810 https://reactome.org/PathwayBrowser/#/R-DRE-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Danio rerio 16474 R-DRE-76031 https://reactome.org/PathwayBrowser/#/R-DRE-76031 2 H2O2 => O2 + 2 H2O IEA Danio rerio 16474 R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 16474 R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 16474 R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 16474 R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 16474 R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 16474 R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 16474 R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 16474 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 16474 R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 16474 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 16474 R-GGA-1236967 https://reactome.org/PathwayBrowser/#/R-GGA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Gallus gallus 16474 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 16474 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 16474 R-GGA-194674 https://reactome.org/PathwayBrowser/#/R-GGA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Gallus gallus 16474 R-GGA-2046083 https://reactome.org/PathwayBrowser/#/R-GGA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Gallus gallus 16474 R-GGA-2046088 https://reactome.org/PathwayBrowser/#/R-GGA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Gallus gallus 16474 R-GGA-2046090 https://reactome.org/PathwayBrowser/#/R-GGA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 16474 R-GGA-2046094 https://reactome.org/PathwayBrowser/#/R-GGA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Gallus gallus 16474 R-GGA-2046095 https://reactome.org/PathwayBrowser/#/R-GGA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Gallus gallus 16474 R-GGA-2046100 https://reactome.org/PathwayBrowser/#/R-GGA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Gallus gallus 16474 R-GGA-209921 https://reactome.org/PathwayBrowser/#/R-GGA-209921 Monoiodinated tyrosine can be deiodinated IEA Gallus gallus 16474 R-GGA-209960 https://reactome.org/PathwayBrowser/#/R-GGA-209960 Diiodinated tyrosine can be deiodinated IEA Gallus gallus 16474 R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 16474 R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 16474 R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 16474 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 16474 R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 16474 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 16474 R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 16474 R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 16474 R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 16474 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 16474 R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 16474 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 16474 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 16474 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 16474 R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 16474 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 16474 R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 16474 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Gallus gallus 16474 R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 16474 R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 16474 R-GGA-350901 https://reactome.org/PathwayBrowser/#/R-GGA-350901 Iodide is organified IEA Gallus gallus 16474 R-GGA-389550 https://reactome.org/PathwayBrowser/#/R-GGA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 16474 R-GGA-389826 https://reactome.org/PathwayBrowser/#/R-GGA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Gallus gallus 16474 R-GGA-5693347 https://reactome.org/PathwayBrowser/#/R-GGA-5693347 CRYM reduces P2C to PPCA IEA Gallus gallus 16474 R-GGA-5693681 https://reactome.org/PathwayBrowser/#/R-GGA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Gallus gallus 16474 R-GGA-6786720 https://reactome.org/PathwayBrowser/#/R-GGA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Gallus gallus 16474 R-GGA-6809810 https://reactome.org/PathwayBrowser/#/R-GGA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Gallus gallus 16474 R-GGA-76031 https://reactome.org/PathwayBrowser/#/R-GGA-76031 2 H2O2 => O2 + 2 H2O IEA Gallus gallus 16474 R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 16474 R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 16474 R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 16474 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 16474 R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 16474 R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 16474 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 16474 R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 16474 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 16474 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 16474 R-HSA-1236967 https://reactome.org/PathwayBrowser/#/R-HSA-1236967 Alkalization of the phagosomal lumen by NOX2 TAS Homo sapiens 16474 R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 16474 R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 16474 R-HSA-194674 https://reactome.org/PathwayBrowser/#/R-HSA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] TAS Homo sapiens 16474 R-HSA-2046083 https://reactome.org/PathwayBrowser/#/R-HSA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA TAS Homo sapiens 16474 R-HSA-2046088 https://reactome.org/PathwayBrowser/#/R-HSA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA TAS Homo sapiens 16474 R-HSA-2046090 https://reactome.org/PathwayBrowser/#/R-HSA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 16474 R-HSA-2046094 https://reactome.org/PathwayBrowser/#/R-HSA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA TAS Homo sapiens 16474 R-HSA-2046095 https://reactome.org/PathwayBrowser/#/R-HSA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA TAS Homo sapiens 16474 R-HSA-2046100 https://reactome.org/PathwayBrowser/#/R-HSA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA TAS Homo sapiens 16474 R-HSA-209921 https://reactome.org/PathwayBrowser/#/R-HSA-209921 Monoiodinated tyrosine can be deiodinated TAS Homo sapiens 16474 R-HSA-209960 https://reactome.org/PathwayBrowser/#/R-HSA-209960 Diiodinated tyrosine can be deiodinated TAS Homo sapiens 16474 R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 16474 R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 16474 R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 16474 R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 16474 R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 16474 R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 16474 R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 16474 R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 16474 R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 16474 R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 16474 R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 16474 R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 16474 R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 16474 R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 16474 R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 16474 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 16474 R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 16474 R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 16474 R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 16474 R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 16474 R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 16474 R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 16474 R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 16474 R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) TAS Homo sapiens 16474 R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 16474 R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 16474 R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 16474 R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 16474 R-HSA-350901 https://reactome.org/PathwayBrowser/#/R-HSA-350901 Iodide is organified TAS Homo sapiens 16474 R-HSA-389550 https://reactome.org/PathwayBrowser/#/R-HSA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 16474 R-HSA-389826 https://reactome.org/PathwayBrowser/#/R-HSA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ TAS Homo sapiens 16474 R-HSA-5602063 https://reactome.org/PathwayBrowser/#/R-HSA-5602063 Defective CYP26B1 does not 4-hydroxylate atRA TAS Homo sapiens 16474 R-HSA-5602242 https://reactome.org/PathwayBrowser/#/R-HSA-5602242 Defective CYP2U1 does not omega-hydroxylate ARA TAS Homo sapiens 16474 R-HSA-5602966 https://reactome.org/PathwayBrowser/#/R-HSA-5602966 Defective FMO3 does not N-oxidise TMA TAS Homo sapiens 16474 R-HSA-5623643 https://reactome.org/PathwayBrowser/#/R-HSA-5623643 RDH13 reduces atRAL to atROL TAS Homo sapiens 16474 R-HSA-5693347 https://reactome.org/PathwayBrowser/#/R-HSA-5693347 CRYM reduces P2C to PPCA TAS Homo sapiens 16474 R-HSA-5693681 https://reactome.org/PathwayBrowser/#/R-HSA-5693681 DUOX1,2 reduce O2 to H2O2 TAS Homo sapiens 16474 R-HSA-6786720 https://reactome.org/PathwayBrowser/#/R-HSA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA TAS Homo sapiens 16474 R-HSA-6809810 https://reactome.org/PathwayBrowser/#/R-HSA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA TAS Homo sapiens 16474 R-HSA-76031 https://reactome.org/PathwayBrowser/#/R-HSA-76031 2 H2O2 => O2 + 2 H2O TAS Homo sapiens 16474 R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 16474 R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 16474 R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 16474 R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 16474 R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 16474 R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 16474 R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 16474 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 16474 R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 16474 R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 16474 R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 16474 R-HSA-9661820 https://reactome.org/PathwayBrowser/#/R-HSA-9661820 Bacterial GUSB hydrolyses BDG to BIL TAS Homo sapiens 16474 R-MMU-1236967 https://reactome.org/PathwayBrowser/#/R-MMU-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Mus musculus 16474 R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 16474 R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 16474 R-MMU-194674 https://reactome.org/PathwayBrowser/#/R-MMU-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Mus musculus 16474 R-MMU-2046083 https://reactome.org/PathwayBrowser/#/R-MMU-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Mus musculus 16474 R-MMU-2046088 https://reactome.org/PathwayBrowser/#/R-MMU-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Mus musculus 16474 R-MMU-2046090 https://reactome.org/PathwayBrowser/#/R-MMU-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 16474 R-MMU-2046094 https://reactome.org/PathwayBrowser/#/R-MMU-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Mus musculus 16474 R-MMU-2046095 https://reactome.org/PathwayBrowser/#/R-MMU-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Mus musculus 16474 R-MMU-2046100 https://reactome.org/PathwayBrowser/#/R-MMU-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Mus musculus 16474 R-MMU-209921 https://reactome.org/PathwayBrowser/#/R-MMU-209921 Monoiodinated tyrosine can be deiodinated IEA Mus musculus 16474 R-MMU-209960 https://reactome.org/PathwayBrowser/#/R-MMU-209960 Diiodinated tyrosine can be deiodinated IEA Mus musculus 16474 R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 16474 R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 16474 R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 16474 R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 16474 R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 16474 R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 16474 R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 16474 R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 16474 R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 16474 R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 16474 R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 16474 R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 16474 R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 16474 R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 16474 R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 16474 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 16474 R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 16474 R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 16474 R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 16474 R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 16474 R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 16474 R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 16474 R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 16474 R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Mus musculus 16474 R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 16474 R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 16474 R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 16474 R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 16474 R-MMU-350901 https://reactome.org/PathwayBrowser/#/R-MMU-350901 Iodide is organified IEA Mus musculus 16474 R-MMU-389550 https://reactome.org/PathwayBrowser/#/R-MMU-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 16474 R-MMU-389826 https://reactome.org/PathwayBrowser/#/R-MMU-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Mus musculus 16474 R-MMU-5623643 https://reactome.org/PathwayBrowser/#/R-MMU-5623643 RDH13 reduces atRAL to atROL IEA Mus musculus 16474 R-MMU-5693347 https://reactome.org/PathwayBrowser/#/R-MMU-5693347 CRYM reduces P2C to PPCA IEA Mus musculus 16474 R-MMU-5693681 https://reactome.org/PathwayBrowser/#/R-MMU-5693681 DUOX1,2 reduce O2 to H2O2 IEA Mus musculus 16474 R-MMU-6786720 https://reactome.org/PathwayBrowser/#/R-MMU-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Mus musculus 16474 R-MMU-6809810 https://reactome.org/PathwayBrowser/#/R-MMU-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Mus musculus 16474 R-MMU-76031 https://reactome.org/PathwayBrowser/#/R-MMU-76031 2 H2O2 => O2 + 2 H2O IEA Mus musculus 16474 R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 16474 R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 16474 R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 16474 R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 16474 R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 16474 R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 16474 R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 16474 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 16474 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 16474 R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 16474 R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 16474 R-PFA-2046088 https://reactome.org/PathwayBrowser/#/R-PFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Plasmodium falciparum 16474 R-PFA-2046094 https://reactome.org/PathwayBrowser/#/R-PFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Plasmodium falciparum 16474 R-PFA-5623643 https://reactome.org/PathwayBrowser/#/R-PFA-5623643 RDH13 reduces atRAL to atROL IEA Plasmodium falciparum 16474 R-RNO-1236967 https://reactome.org/PathwayBrowser/#/R-RNO-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Rattus norvegicus 16474 R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 16474 R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 16474 R-RNO-194674 https://reactome.org/PathwayBrowser/#/R-RNO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Rattus norvegicus 16474 R-RNO-2046083 https://reactome.org/PathwayBrowser/#/R-RNO-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Rattus norvegicus 16474 R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus 16474 R-RNO-2046090 https://reactome.org/PathwayBrowser/#/R-RNO-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 16474 R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus 16474 R-RNO-2046095 https://reactome.org/PathwayBrowser/#/R-RNO-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Rattus norvegicus 16474 R-RNO-2046100 https://reactome.org/PathwayBrowser/#/R-RNO-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Rattus norvegicus 16474 R-RNO-209921 https://reactome.org/PathwayBrowser/#/R-RNO-209921 Monoiodinated tyrosine can be deiodinated IEA Rattus norvegicus 16474 R-RNO-209960 https://reactome.org/PathwayBrowser/#/R-RNO-209960 Diiodinated tyrosine can be deiodinated IEA Rattus norvegicus 16474 R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 16474 R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 16474 R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 16474 R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 16474 R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 16474 R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 16474 R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 16474 R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 16474 R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 16474 R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 16474 R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 16474 R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 16474 R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 16474 R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 16474 R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 16474 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 16474 R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 16474 R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 16474 R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 16474 R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 16474 R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 16474 R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 16474 R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 16474 R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Rattus norvegicus 16474 R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 16474 R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 16474 R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 16474 R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 16474 R-RNO-350901 https://reactome.org/PathwayBrowser/#/R-RNO-350901 Iodide is organified IEA Rattus norvegicus 16474 R-RNO-389550 https://reactome.org/PathwayBrowser/#/R-RNO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 16474 R-RNO-389826 https://reactome.org/PathwayBrowser/#/R-RNO-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Rattus norvegicus 16474 R-RNO-5623643 https://reactome.org/PathwayBrowser/#/R-RNO-5623643 RDH13 reduces atRAL to atROL IEA Rattus norvegicus 16474 R-RNO-5693347 https://reactome.org/PathwayBrowser/#/R-RNO-5693347 CRYM reduces P2C to PPCA IEA Rattus norvegicus 16474 R-RNO-5693681 https://reactome.org/PathwayBrowser/#/R-RNO-5693681 DUOX1,2 reduce O2 to H2O2 IEA Rattus norvegicus 16474 R-RNO-6786720 https://reactome.org/PathwayBrowser/#/R-RNO-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Rattus norvegicus 16474 R-RNO-6809810 https://reactome.org/PathwayBrowser/#/R-RNO-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Rattus norvegicus 16474 R-RNO-76031 https://reactome.org/PathwayBrowser/#/R-RNO-76031 2 H2O2 => O2 + 2 H2O IEA Rattus norvegicus 16474 R-RNO-76354 https://reactome.org/PathwayBrowser/#/R-RNO-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Rattus norvegicus 16474 R-RNO-76373 https://reactome.org/PathwayBrowser/#/R-RNO-76373 N-hydroxylation of 4-aminobiphenyl IEA Rattus norvegicus 16474 R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 16474 R-RNO-76397 https://reactome.org/PathwayBrowser/#/R-RNO-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Rattus norvegicus 16474 R-RNO-76416 https://reactome.org/PathwayBrowser/#/R-RNO-76416 Benzene is hydroxylated to phenol IEA Rattus norvegicus 16474 R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 16474 R-RNO-76453 https://reactome.org/PathwayBrowser/#/R-RNO-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Rattus norvegicus 16474 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 16474 R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 16474 R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 16474 R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 16474 R-SCE-194674 https://reactome.org/PathwayBrowser/#/R-SCE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Saccharomyces cerevisiae 16474 R-SCE-2046088 https://reactome.org/PathwayBrowser/#/R-SCE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Saccharomyces cerevisiae 16474 R-SCE-2046094 https://reactome.org/PathwayBrowser/#/R-SCE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Saccharomyces cerevisiae 16474 R-SCE-389550 https://reactome.org/PathwayBrowser/#/R-SCE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 16474 R-SCE-5693347 https://reactome.org/PathwayBrowser/#/R-SCE-5693347 CRYM reduces P2C to PPCA IEA Saccharomyces cerevisiae 16474 R-SCE-5693681 https://reactome.org/PathwayBrowser/#/R-SCE-5693681 DUOX1,2 reduce O2 to H2O2 IEA Saccharomyces cerevisiae 16474 R-SCE-6786720 https://reactome.org/PathwayBrowser/#/R-SCE-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Saccharomyces cerevisiae 16474 R-SCE-6790127 https://reactome.org/PathwayBrowser/#/R-SCE-6790127 SMM1 (DUS2) reduces uridine-20 to dihydrouridine in tRNA(Leu) TAS Saccharomyces cerevisiae 16474 R-SCE-76031 https://reactome.org/PathwayBrowser/#/R-SCE-76031 2 H2O2 => O2 + 2 H2O IEA Saccharomyces cerevisiae 16474 R-SPO-194674 https://reactome.org/PathwayBrowser/#/R-SPO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Schizosaccharomyces pombe 16474 R-SPO-2046088 https://reactome.org/PathwayBrowser/#/R-SPO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Schizosaccharomyces pombe 16474 R-SPO-2046094 https://reactome.org/PathwayBrowser/#/R-SPO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Schizosaccharomyces pombe 16474 R-SPO-389550 https://reactome.org/PathwayBrowser/#/R-SPO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 16474 R-SPO-5693347 https://reactome.org/PathwayBrowser/#/R-SPO-5693347 CRYM reduces P2C to PPCA IEA Schizosaccharomyces pombe 16474 R-SPO-76031 https://reactome.org/PathwayBrowser/#/R-SPO-76031 2 H2O2 => O2 + 2 H2O IEA Schizosaccharomyces pombe 16474 R-SSC-1236967 https://reactome.org/PathwayBrowser/#/R-SSC-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Sus scrofa 16474 R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 16474 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 16474 R-SSC-194674 https://reactome.org/PathwayBrowser/#/R-SSC-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Sus scrofa 16474 R-SSC-2046083 https://reactome.org/PathwayBrowser/#/R-SSC-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Sus scrofa 16474 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa 16474 R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 16474 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa 16474 R-SSC-2046095 https://reactome.org/PathwayBrowser/#/R-SSC-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Sus scrofa 16474 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa 16474 R-SSC-209921 https://reactome.org/PathwayBrowser/#/R-SSC-209921 Monoiodinated tyrosine can be deiodinated IEA Sus scrofa 16474 R-SSC-209960 https://reactome.org/PathwayBrowser/#/R-SSC-209960 Diiodinated tyrosine can be deiodinated IEA Sus scrofa 16474 R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 16474 R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 16474 R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa 16474 R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 16474 R-SSC-211904 https://reactome.org/PathwayBrowser/#/R-SSC-211904 CYP4F12 18-hydroxylates ARA IEA Sus scrofa 16474 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 16474 R-SSC-211919 https://reactome.org/PathwayBrowser/#/R-SSC-211919 CYP4F8 19-hydroxylates PGH2 IEA Sus scrofa 16474 R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa 16474 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 16474 R-SSC-211948 https://reactome.org/PathwayBrowser/#/R-SSC-211948 CYP3A4 can N-demethylate loperamide IEA Sus scrofa 16474 R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 16474 R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa 16474 R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa 16474 R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa 16474 R-SSC-211968 https://reactome.org/PathwayBrowser/#/R-SSC-211968 CYP2W1 oxidises INDOL IEA Sus scrofa 16474 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 16474 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 16474 R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa 16474 R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 16474 R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa 16474 R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 16474 R-SSC-213175 https://reactome.org/PathwayBrowser/#/R-SSC-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Sus scrofa 16474 R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa 16474 R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Sus scrofa 16474 R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa 16474 R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa 16474 R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 16474 R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 16474 R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa 16474 R-SSC-389550 https://reactome.org/PathwayBrowser/#/R-SSC-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 16474 R-SSC-389826 https://reactome.org/PathwayBrowser/#/R-SSC-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Sus scrofa 16474 R-SSC-5623643 https://reactome.org/PathwayBrowser/#/R-SSC-5623643 RDH13 reduces atRAL to atROL IEA Sus scrofa 16474 R-SSC-5693347 https://reactome.org/PathwayBrowser/#/R-SSC-5693347 CRYM reduces P2C to PPCA IEA Sus scrofa 16474 R-SSC-5693681 https://reactome.org/PathwayBrowser/#/R-SSC-5693681 DUOX1,2 reduce O2 to H2O2 IEA Sus scrofa 16474 R-SSC-6786720 https://reactome.org/PathwayBrowser/#/R-SSC-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Sus scrofa 16474 R-SSC-6809810 https://reactome.org/PathwayBrowser/#/R-SSC-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Sus scrofa 16474 R-SSC-76031 https://reactome.org/PathwayBrowser/#/R-SSC-76031 2 H2O2 => O2 + 2 H2O IEA Sus scrofa 16474 R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa 16474 R-SSC-76373 https://reactome.org/PathwayBrowser/#/R-SSC-76373 N-hydroxylation of 4-aminobiphenyl IEA Sus scrofa 16474 R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 16474 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa 16474 R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa 16474 R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 16474 R-SSC-76453 https://reactome.org/PathwayBrowser/#/R-SSC-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Sus scrofa 16474 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 16474 R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 16474 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 16474 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 16474 R-XTR-1236967 https://reactome.org/PathwayBrowser/#/R-XTR-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Xenopus tropicalis 16474 R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 16474 R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 16474 R-XTR-194674 https://reactome.org/PathwayBrowser/#/R-XTR-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Xenopus tropicalis 16474 R-XTR-2046083 https://reactome.org/PathwayBrowser/#/R-XTR-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Xenopus tropicalis 16474 R-XTR-2046088 https://reactome.org/PathwayBrowser/#/R-XTR-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Xenopus tropicalis 16474 R-XTR-2046090 https://reactome.org/PathwayBrowser/#/R-XTR-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Xenopus tropicalis 16474 R-XTR-2046094 https://reactome.org/PathwayBrowser/#/R-XTR-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Xenopus tropicalis 16474 R-XTR-2046095 https://reactome.org/PathwayBrowser/#/R-XTR-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Xenopus tropicalis 16474 R-XTR-2046100 https://reactome.org/PathwayBrowser/#/R-XTR-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Xenopus tropicalis 16474 R-XTR-209921 https://reactome.org/PathwayBrowser/#/R-XTR-209921 Monoiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 16474 R-XTR-209960 https://reactome.org/PathwayBrowser/#/R-XTR-209960 Diiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 16474 R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 16474 R-XTR-211881 https://reactome.org/PathwayBrowser/#/R-XTR-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Xenopus tropicalis 16474 R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 16474 R-XTR-211904 https://reactome.org/PathwayBrowser/#/R-XTR-211904 CYP4F12 18-hydroxylates ARA IEA Xenopus tropicalis 16474 R-XTR-211919 https://reactome.org/PathwayBrowser/#/R-XTR-211919 CYP4F8 19-hydroxylates PGH2 IEA Xenopus tropicalis 16474 R-XTR-211924 https://reactome.org/PathwayBrowser/#/R-XTR-211924 CYP4B1 12-hydroxylates ARA IEA Xenopus tropicalis 16474 R-XTR-211948 https://reactome.org/PathwayBrowser/#/R-XTR-211948 CYP3A4 can N-demethylate loperamide IEA Xenopus tropicalis 16474 R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 16474 R-XTR-211960 https://reactome.org/PathwayBrowser/#/R-XTR-211960 CYP2U1 19-hydroxylates ARA IEA Xenopus tropicalis 16474 R-XTR-211962 https://reactome.org/PathwayBrowser/#/R-XTR-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Xenopus tropicalis 16474 R-XTR-211966 https://reactome.org/PathwayBrowser/#/R-XTR-211966 CYP2D6 4-hydroxylates debrisoquine IEA Xenopus tropicalis 16474 R-XTR-211968 https://reactome.org/PathwayBrowser/#/R-XTR-211968 CYP2W1 oxidises INDOL IEA Xenopus tropicalis 16474 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 16474 R-XTR-211991 https://reactome.org/PathwayBrowser/#/R-XTR-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Xenopus tropicalis 16474 R-XTR-212005 https://reactome.org/PathwayBrowser/#/R-XTR-212005 CYP2F1 dehydrogenates 3-methylindole IEA Xenopus tropicalis 16474 R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 16474 R-XTR-213175 https://reactome.org/PathwayBrowser/#/R-XTR-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 16474 R-XTR-215526 https://reactome.org/PathwayBrowser/#/R-XTR-215526 CYP4F3 20-hydroxylates LTB4 IEA Xenopus tropicalis 16474 R-XTR-2161814 https://reactome.org/PathwayBrowser/#/R-XTR-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Xenopus tropicalis 16474 R-XTR-2161940 https://reactome.org/PathwayBrowser/#/R-XTR-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Xenopus tropicalis 16474 R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 16474 R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 16474 R-XTR-389550 https://reactome.org/PathwayBrowser/#/R-XTR-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 16474 R-XTR-389826 https://reactome.org/PathwayBrowser/#/R-XTR-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Xenopus tropicalis 16474 R-XTR-5623643 https://reactome.org/PathwayBrowser/#/R-XTR-5623643 RDH13 reduces atRAL to atROL IEA Xenopus tropicalis 16474 R-XTR-5693347 https://reactome.org/PathwayBrowser/#/R-XTR-5693347 CRYM reduces P2C to PPCA IEA Xenopus tropicalis 16474 R-XTR-5693681 https://reactome.org/PathwayBrowser/#/R-XTR-5693681 DUOX1,2 reduce O2 to H2O2 IEA Xenopus tropicalis 16474 R-XTR-76031 https://reactome.org/PathwayBrowser/#/R-XTR-76031 2 H2O2 => O2 + 2 H2O IEA Xenopus tropicalis 16474 R-XTR-76354 https://reactome.org/PathwayBrowser/#/R-XTR-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Xenopus tropicalis 16474 R-XTR-76397 https://reactome.org/PathwayBrowser/#/R-XTR-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Xenopus tropicalis 16474 R-XTR-76416 https://reactome.org/PathwayBrowser/#/R-XTR-76416 Benzene is hydroxylated to phenol IEA Xenopus tropicalis 16474 R-XTR-76453 https://reactome.org/PathwayBrowser/#/R-XTR-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Xenopus tropicalis 16474 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 16474 R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 16474 R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 16480 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 16480 R-BTA-418436 https://reactome.org/PathwayBrowser/#/R-BTA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Bos taurus 16480 R-BTA-5340226 https://reactome.org/PathwayBrowser/#/R-BTA-5340226 CYGB dioxygenates NO IEA Bos taurus 16480 R-BTA-9012374 https://reactome.org/PathwayBrowser/#/R-BTA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Bos taurus 16480 R-BTA-9620103 https://reactome.org/PathwayBrowser/#/R-BTA-9620103 ALDH2 transforms GTN to NO IEA Bos taurus 16480 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 16480 R-BTA-9621179 https://reactome.org/PathwayBrowser/#/R-BTA-9621179 Cinaciguat binds sGC:NO IEA Bos taurus 16480 R-BTA-9854368 https://reactome.org/PathwayBrowser/#/R-BTA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Bos taurus 16480 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 16480 R-CEL-5340226 https://reactome.org/PathwayBrowser/#/R-CEL-5340226 CYGB dioxygenates NO IEA Caenorhabditis elegans 16480 R-CEL-9012374 https://reactome.org/PathwayBrowser/#/R-CEL-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Caenorhabditis elegans 16480 R-CEL-9620103 https://reactome.org/PathwayBrowser/#/R-CEL-9620103 ALDH2 transforms GTN to NO IEA Caenorhabditis elegans 16480 R-CEL-9854368 https://reactome.org/PathwayBrowser/#/R-CEL-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Caenorhabditis elegans 16480 R-CFA-418436 https://reactome.org/PathwayBrowser/#/R-CFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Canis familiaris 16480 R-CFA-5340226 https://reactome.org/PathwayBrowser/#/R-CFA-5340226 CYGB dioxygenates NO IEA Canis familiaris 16480 R-CFA-9012374 https://reactome.org/PathwayBrowser/#/R-CFA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Canis familiaris 16480 R-CFA-9620103 https://reactome.org/PathwayBrowser/#/R-CFA-9620103 ALDH2 transforms GTN to NO IEA Canis familiaris 16480 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 16480 R-CFA-9621179 https://reactome.org/PathwayBrowser/#/R-CFA-9621179 Cinaciguat binds sGC:NO IEA Canis familiaris 16480 R-CFA-9854368 https://reactome.org/PathwayBrowser/#/R-CFA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Canis familiaris 16480 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 16480 R-DDI-418436 https://reactome.org/PathwayBrowser/#/R-DDI-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Dictyostelium discoideum 16480 R-DDI-9012374 https://reactome.org/PathwayBrowser/#/R-DDI-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Dictyostelium discoideum 16480 R-DDI-9620103 https://reactome.org/PathwayBrowser/#/R-DDI-9620103 ALDH2 transforms GTN to NO IEA Dictyostelium discoideum 16480 R-DDI-9854368 https://reactome.org/PathwayBrowser/#/R-DDI-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Dictyostelium discoideum 16480 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 16480 R-DME-418436 https://reactome.org/PathwayBrowser/#/R-DME-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Drosophila melanogaster 16480 R-DME-9012374 https://reactome.org/PathwayBrowser/#/R-DME-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Drosophila melanogaster 16480 R-DME-9620103 https://reactome.org/PathwayBrowser/#/R-DME-9620103 ALDH2 transforms GTN to NO IEA Drosophila melanogaster 16480 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 16480 R-DME-9621179 https://reactome.org/PathwayBrowser/#/R-DME-9621179 Cinaciguat binds sGC:NO IEA Drosophila melanogaster 16480 R-DME-9854368 https://reactome.org/PathwayBrowser/#/R-DME-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Drosophila melanogaster 16480 R-DRE-418436 https://reactome.org/PathwayBrowser/#/R-DRE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Danio rerio 16480 R-DRE-5340226 https://reactome.org/PathwayBrowser/#/R-DRE-5340226 CYGB dioxygenates NO IEA Danio rerio 16480 R-DRE-9012374 https://reactome.org/PathwayBrowser/#/R-DRE-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Danio rerio 16480 R-DRE-9620103 https://reactome.org/PathwayBrowser/#/R-DRE-9620103 ALDH2 transforms GTN to NO IEA Danio rerio 16480 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 16480 R-DRE-9621179 https://reactome.org/PathwayBrowser/#/R-DRE-9621179 Cinaciguat binds sGC:NO IEA Danio rerio 16480 R-DRE-9854368 https://reactome.org/PathwayBrowser/#/R-DRE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Danio rerio 16480 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 16480 R-GGA-418436 https://reactome.org/PathwayBrowser/#/R-GGA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Gallus gallus 16480 R-GGA-5340226 https://reactome.org/PathwayBrowser/#/R-GGA-5340226 CYGB dioxygenates NO IEA Gallus gallus 16480 R-GGA-9012374 https://reactome.org/PathwayBrowser/#/R-GGA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Gallus gallus 16480 R-GGA-9620103 https://reactome.org/PathwayBrowser/#/R-GGA-9620103 ALDH2 transforms GTN to NO IEA Gallus gallus 16480 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 16480 R-GGA-9621179 https://reactome.org/PathwayBrowser/#/R-GGA-9621179 Cinaciguat binds sGC:NO IEA Gallus gallus 16480 R-GGA-9854368 https://reactome.org/PathwayBrowser/#/R-GGA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Gallus gallus 16480 R-HSA-1222407 https://reactome.org/PathwayBrowser/#/R-HSA-1222407 Superoxide and nitric oxide react to peroxynitrite TAS Homo sapiens 16480 R-HSA-1222512 https://reactome.org/PathwayBrowser/#/R-HSA-1222512 Nitric oxide oxidizes to nitrosyl ion TAS Homo sapiens 16480 R-HSA-1222662 https://reactome.org/PathwayBrowser/#/R-HSA-1222662 Nitric oxide enters the bacterium TAS Homo sapiens 16480 R-HSA-1222686 https://reactome.org/PathwayBrowser/#/R-HSA-1222686 Nitric oxide diffuses into the phagosome TAS Homo sapiens 16480 R-HSA-1497878 https://reactome.org/PathwayBrowser/#/R-HSA-1497878 Superoxide reacts rapidly with NO to form peroxynitrite (ONOO-) TAS Homo sapiens 16480 R-HSA-1500761 https://reactome.org/PathwayBrowser/#/R-HSA-1500761 Nitrogen dioxide is reduced to NO by F420 TAS Homo sapiens 16480 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 16480 R-HSA-3697855 https://reactome.org/PathwayBrowser/#/R-HSA-3697855 Superoxide and nitric oxide react to form peroxynitrite in mitochondria TAS Homo sapiens 16480 R-HSA-392143 https://reactome.org/PathwayBrowser/#/R-HSA-392143 NO binds to Guanylate Cyclase IEA Homo sapiens 16480 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 16480 R-HSA-418436 https://reactome.org/PathwayBrowser/#/R-HSA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) TAS Homo sapiens 16480 R-HSA-5340226 https://reactome.org/PathwayBrowser/#/R-HSA-5340226 CYGB dioxygenates NO TAS Homo sapiens 16480 R-HSA-6803989 https://reactome.org/PathwayBrowser/#/R-HSA-6803989 Nitric oxide and O2 react to NO2 TAS Homo sapiens 16480 R-HSA-6804006 https://reactome.org/PathwayBrowser/#/R-HSA-6804006 NO and NO2 react to N2O3 TAS Homo sapiens 16480 R-HSA-8942052 https://reactome.org/PathwayBrowser/#/R-HSA-8942052 Superoxide and nitric oxide react to peroxynitrite in the phagosome TAS Homo sapiens 16480 R-HSA-9012374 https://reactome.org/PathwayBrowser/#/R-HSA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space TAS Homo sapiens 16480 R-HSA-9620103 https://reactome.org/PathwayBrowser/#/R-HSA-9620103 ALDH2 transforms GTN to NO TAS Homo sapiens 16480 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 16480 R-HSA-9621179 https://reactome.org/PathwayBrowser/#/R-HSA-9621179 Cinaciguat binds sGC:NO TAS Homo sapiens 16480 R-HSA-9709885 https://reactome.org/PathwayBrowser/#/R-HSA-9709885 BIL scavenges NO TAS Homo sapiens 16480 R-HSA-9854368 https://reactome.org/PathwayBrowser/#/R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S TAS Homo sapiens 16480 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 16480 R-MMU-418436 https://reactome.org/PathwayBrowser/#/R-MMU-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Mus musculus 16480 R-MMU-5340226 https://reactome.org/PathwayBrowser/#/R-MMU-5340226 CYGB dioxygenates NO IEA Mus musculus 16480 R-MMU-9012374 https://reactome.org/PathwayBrowser/#/R-MMU-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Mus musculus 16480 R-MMU-9620103 https://reactome.org/PathwayBrowser/#/R-MMU-9620103 ALDH2 transforms GTN to NO IEA Mus musculus 16480 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 16480 R-MMU-9621179 https://reactome.org/PathwayBrowser/#/R-MMU-9621179 Cinaciguat binds sGC:NO IEA Mus musculus 16480 R-MMU-9854368 https://reactome.org/PathwayBrowser/#/R-MMU-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Mus musculus 16480 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 16480 R-PFA-418436 https://reactome.org/PathwayBrowser/#/R-PFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Plasmodium falciparum 16480 R-PFA-9012374 https://reactome.org/PathwayBrowser/#/R-PFA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Plasmodium falciparum 16480 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 16480 R-RNO-418436 https://reactome.org/PathwayBrowser/#/R-RNO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Rattus norvegicus 16480 R-RNO-427279 https://reactome.org/PathwayBrowser/#/R-RNO-427279 NO binds to Guanylate Cyclase TAS Rattus norvegicus 16480 R-RNO-5340226 https://reactome.org/PathwayBrowser/#/R-RNO-5340226 CYGB dioxygenates NO IEA Rattus norvegicus 16480 R-RNO-9012374 https://reactome.org/PathwayBrowser/#/R-RNO-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Rattus norvegicus 16480 R-RNO-9620103 https://reactome.org/PathwayBrowser/#/R-RNO-9620103 ALDH2 transforms GTN to NO IEA Rattus norvegicus 16480 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 16480 R-RNO-9621179 https://reactome.org/PathwayBrowser/#/R-RNO-9621179 Cinaciguat binds sGC:NO IEA Rattus norvegicus 16480 R-RNO-9854368 https://reactome.org/PathwayBrowser/#/R-RNO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Rattus norvegicus 16480 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 16480 R-SCE-418436 https://reactome.org/PathwayBrowser/#/R-SCE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Saccharomyces cerevisiae 16480 R-SCE-9012374 https://reactome.org/PathwayBrowser/#/R-SCE-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Saccharomyces cerevisiae 16480 R-SCE-9620103 https://reactome.org/PathwayBrowser/#/R-SCE-9620103 ALDH2 transforms GTN to NO IEA Saccharomyces cerevisiae 16480 R-SCE-9854368 https://reactome.org/PathwayBrowser/#/R-SCE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Saccharomyces cerevisiae 16480 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 16480 R-SPO-418436 https://reactome.org/PathwayBrowser/#/R-SPO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Schizosaccharomyces pombe 16480 R-SPO-9012374 https://reactome.org/PathwayBrowser/#/R-SPO-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Schizosaccharomyces pombe 16480 R-SPO-9620103 https://reactome.org/PathwayBrowser/#/R-SPO-9620103 ALDH2 transforms GTN to NO IEA Schizosaccharomyces pombe 16480 R-SPO-9854368 https://reactome.org/PathwayBrowser/#/R-SPO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Schizosaccharomyces pombe 16480 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 16480 R-SSC-418436 https://reactome.org/PathwayBrowser/#/R-SSC-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Sus scrofa 16480 R-SSC-5340226 https://reactome.org/PathwayBrowser/#/R-SSC-5340226 CYGB dioxygenates NO IEA Sus scrofa 16480 R-SSC-9012374 https://reactome.org/PathwayBrowser/#/R-SSC-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Sus scrofa 16480 R-SSC-9620103 https://reactome.org/PathwayBrowser/#/R-SSC-9620103 ALDH2 transforms GTN to NO IEA Sus scrofa 16480 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 16480 R-SSC-9621179 https://reactome.org/PathwayBrowser/#/R-SSC-9621179 Cinaciguat binds sGC:NO IEA Sus scrofa 16480 R-SSC-9854368 https://reactome.org/PathwayBrowser/#/R-SSC-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Sus scrofa 16480 R-XTR-5340226 https://reactome.org/PathwayBrowser/#/R-XTR-5340226 CYGB dioxygenates NO IEA Xenopus tropicalis 16480 R-XTR-9012374 https://reactome.org/PathwayBrowser/#/R-XTR-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Xenopus tropicalis 16480 R-XTR-9620103 https://reactome.org/PathwayBrowser/#/R-XTR-9620103 ALDH2 transforms GTN to NO IEA Xenopus tropicalis 16480 R-XTR-9854368 https://reactome.org/PathwayBrowser/#/R-XTR-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Xenopus tropicalis 16485 R-BTA-193965 https://reactome.org/PathwayBrowser/#/R-BTA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Bos taurus 16485 R-BTA-193995 https://reactome.org/PathwayBrowser/#/R-BTA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Bos taurus 16485 R-CFA-193965 https://reactome.org/PathwayBrowser/#/R-CFA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Canis familiaris 16485 R-CFA-193995 https://reactome.org/PathwayBrowser/#/R-CFA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Canis familiaris 16485 R-HSA-193965 https://reactome.org/PathwayBrowser/#/R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO TAS Homo sapiens 16485 R-HSA-193995 https://reactome.org/PathwayBrowser/#/R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST TAS Homo sapiens 16485 R-HSA-6785244 https://reactome.org/PathwayBrowser/#/R-HSA-6785244 Defective CYP11B2 does not oxidise 18HCORST TAS Homo sapiens 16485 R-MMU-193965 https://reactome.org/PathwayBrowser/#/R-MMU-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Mus musculus 16485 R-MMU-193995 https://reactome.org/PathwayBrowser/#/R-MMU-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Mus musculus 16485 R-RNO-193965 https://reactome.org/PathwayBrowser/#/R-RNO-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Rattus norvegicus 16485 R-RNO-193995 https://reactome.org/PathwayBrowser/#/R-RNO-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Rattus norvegicus 16485 R-SSC-193965 https://reactome.org/PathwayBrowser/#/R-SSC-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Sus scrofa 16485 R-SSC-193995 https://reactome.org/PathwayBrowser/#/R-SSC-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Sus scrofa 16485 R-XTR-193965 https://reactome.org/PathwayBrowser/#/R-XTR-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Xenopus tropicalis 16485 R-XTR-193995 https://reactome.org/PathwayBrowser/#/R-XTR-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Xenopus tropicalis 16494 R-BTA-429581 https://reactome.org/PathwayBrowser/#/R-BTA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Bos taurus 16494 R-CFA-429581 https://reactome.org/PathwayBrowser/#/R-CFA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Canis familiaris 16494 R-DRE-429581 https://reactome.org/PathwayBrowser/#/R-DRE-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Danio rerio 16494 R-GGA-429581 https://reactome.org/PathwayBrowser/#/R-GGA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Gallus gallus 16494 R-HSA-429581 https://reactome.org/PathwayBrowser/#/R-HSA-429581 SLC5A6 transports vitamins from extracellular region to cytosol TAS Homo sapiens 16494 R-MMU-429581 https://reactome.org/PathwayBrowser/#/R-MMU-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Mus musculus 16494 R-RNO-429581 https://reactome.org/PathwayBrowser/#/R-RNO-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Rattus norvegicus 16494 R-SSC-429581 https://reactome.org/PathwayBrowser/#/R-SSC-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Sus scrofa 16494 R-XTR-429581 https://reactome.org/PathwayBrowser/#/R-XTR-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Xenopus tropicalis 16496 R-BTA-191999 https://reactome.org/PathwayBrowser/#/R-BTA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Bos taurus 16496 R-BTA-192036 https://reactome.org/PathwayBrowser/#/R-BTA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Bos taurus 16496 R-CEL-192036 https://reactome.org/PathwayBrowser/#/R-CEL-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Caenorhabditis elegans 16496 R-CFA-191999 https://reactome.org/PathwayBrowser/#/R-CFA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Canis familiaris 16496 R-DDI-192036 https://reactome.org/PathwayBrowser/#/R-DDI-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Dictyostelium discoideum 16496 R-DME-192036 https://reactome.org/PathwayBrowser/#/R-DME-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Drosophila melanogaster 16496 R-HSA-191999 https://reactome.org/PathwayBrowser/#/R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol TAS Homo sapiens 16496 R-HSA-192010 https://reactome.org/PathwayBrowser/#/R-HSA-192010 5beta-cholestan-3alpha, 7alpha, 12alpha-triol is translocated from the cytosol to the mitochondrial matrix TAS Homo sapiens 16496 R-HSA-192036 https://reactome.org/PathwayBrowser/#/R-HSA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol TAS Homo sapiens 16496 R-HSA-5602170 https://reactome.org/PathwayBrowser/#/R-HSA-5602170 CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol TAS Homo sapiens 16496 R-MMU-191999 https://reactome.org/PathwayBrowser/#/R-MMU-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Mus musculus 16496 R-MMU-192036 https://reactome.org/PathwayBrowser/#/R-MMU-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Mus musculus 16496 R-RNO-191999 https://reactome.org/PathwayBrowser/#/R-RNO-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Rattus norvegicus 16496 R-RNO-192036 https://reactome.org/PathwayBrowser/#/R-RNO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Rattus norvegicus 16496 R-SCE-192036 https://reactome.org/PathwayBrowser/#/R-SCE-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Saccharomyces cerevisiae 16496 R-SPO-192036 https://reactome.org/PathwayBrowser/#/R-SPO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Schizosaccharomyces pombe 16496 R-SSC-191999 https://reactome.org/PathwayBrowser/#/R-SSC-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Sus scrofa 16496 R-SSC-192036 https://reactome.org/PathwayBrowser/#/R-SSC-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Sus scrofa 16496 R-XTR-192036 https://reactome.org/PathwayBrowser/#/R-XTR-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Xenopus tropicalis 16503 R-BTA-2408524 https://reactome.org/PathwayBrowser/#/R-BTA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Bos taurus 16503 R-BTA-2408527 https://reactome.org/PathwayBrowser/#/R-BTA-2408527 SeO3(2-) is reduced to H2Se by TXNRD1 TAS Bos taurus 16503 R-CEL-2408524 https://reactome.org/PathwayBrowser/#/R-CEL-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Caenorhabditis elegans 16503 R-CEL-8959510 https://reactome.org/PathwayBrowser/#/R-CEL-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Caenorhabditis elegans 16503 R-CFA-2408524 https://reactome.org/PathwayBrowser/#/R-CFA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Canis familiaris 16503 R-CFA-8959510 https://reactome.org/PathwayBrowser/#/R-CFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Canis familiaris 16503 R-DDI-8959510 https://reactome.org/PathwayBrowser/#/R-DDI-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Dictyostelium discoideum 16503 R-DME-8959510 https://reactome.org/PathwayBrowser/#/R-DME-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Drosophila melanogaster 16503 R-DRE-2408524 https://reactome.org/PathwayBrowser/#/R-DRE-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Danio rerio 16503 R-DRE-8959510 https://reactome.org/PathwayBrowser/#/R-DRE-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Danio rerio 16503 R-GGA-2408524 https://reactome.org/PathwayBrowser/#/R-GGA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Gallus gallus 16503 R-HSA-2408500 https://reactome.org/PathwayBrowser/#/R-HSA-2408500 GSSeH condenses with GSH to form H2Se and GSSG IEA Homo sapiens 16503 R-HSA-2408524 https://reactome.org/PathwayBrowser/#/R-HSA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer TAS Homo sapiens 16503 R-HSA-2408530 https://reactome.org/PathwayBrowser/#/R-HSA-2408530 MeSeH is hydrolysed to H2Se by methylselenol demethylase IEA Homo sapiens 16503 R-HSA-2408536 https://reactome.org/PathwayBrowser/#/R-HSA-2408536 H2Se is methylated to MeSeH by H2Se methyltransferase IEA Homo sapiens 16503 R-HSA-2408558 https://reactome.org/PathwayBrowser/#/R-HSA-2408558 SeO3(2-) is reduced to H2Se by TXNRD1 IEA Homo sapiens 16503 R-HSA-8959510 https://reactome.org/PathwayBrowser/#/R-HSA-8959510 SEPHS2 phosphorylates H2Se to form SELP TAS Homo sapiens 16503 R-MMU-2408524 https://reactome.org/PathwayBrowser/#/R-MMU-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Mus musculus 16503 R-MMU-8959510 https://reactome.org/PathwayBrowser/#/R-MMU-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Mus musculus 16503 R-PFA-8959510 https://reactome.org/PathwayBrowser/#/R-PFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Plasmodium falciparum 16503 R-RNO-2408511 https://reactome.org/PathwayBrowser/#/R-RNO-2408511 H2Se is methylated to MeSeH by H2Se methyltransferase TAS Rattus norvegicus 16503 R-RNO-2408520 https://reactome.org/PathwayBrowser/#/R-RNO-2408520 GSSeH condenses with GSH to form H2Se and GSSG TAS Rattus norvegicus 16503 R-RNO-2408521 https://reactome.org/PathwayBrowser/#/R-RNO-2408521 MeSeH is hydrolysed to H2Se by methylselenol demethylase TAS Rattus norvegicus 16503 R-RNO-2408524 https://reactome.org/PathwayBrowser/#/R-RNO-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Rattus norvegicus 16503 R-RNO-8959510 https://reactome.org/PathwayBrowser/#/R-RNO-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Rattus norvegicus 16503 R-SSC-2408524 https://reactome.org/PathwayBrowser/#/R-SSC-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Sus scrofa 16503 R-SSC-8959510 https://reactome.org/PathwayBrowser/#/R-SSC-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Sus scrofa 16503 R-XTR-2408524 https://reactome.org/PathwayBrowser/#/R-XTR-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Xenopus tropicalis 16507 R-BTA-1855225 https://reactome.org/PathwayBrowser/#/R-BTA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Bos taurus 16507 R-CFA-1855225 https://reactome.org/PathwayBrowser/#/R-CFA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Canis familiaris 16507 R-DDI-1855225 https://reactome.org/PathwayBrowser/#/R-DDI-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 16507 R-DRE-1855225 https://reactome.org/PathwayBrowser/#/R-DRE-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Danio rerio 16507 R-GGA-1855225 https://reactome.org/PathwayBrowser/#/R-GGA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Gallus gallus 16507 R-HSA-1855225 https://reactome.org/PathwayBrowser/#/R-HSA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen TAS Homo sapiens 16507 R-MMU-1855225 https://reactome.org/PathwayBrowser/#/R-MMU-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Mus musculus 16507 R-RNO-1855225 https://reactome.org/PathwayBrowser/#/R-RNO-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Rattus norvegicus 16507 R-SSC-1855225 https://reactome.org/PathwayBrowser/#/R-SSC-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Sus scrofa 16507 R-XTR-1855225 https://reactome.org/PathwayBrowser/#/R-XTR-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Xenopus tropicalis 16516 R-BTA-110311 https://reactome.org/PathwayBrowser/#/R-BTA-110311 POLZ extends translesion synthesis IEA Bos taurus 16516 R-BTA-110319 https://reactome.org/PathwayBrowser/#/R-BTA-110319 Elongation by POLH IEA Bos taurus 16516 R-BTA-110368 https://reactome.org/PathwayBrowser/#/R-BTA-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Bos taurus 16516 R-BTA-111253 https://reactome.org/PathwayBrowser/#/R-BTA-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Bos taurus 16516 R-BTA-5649723 https://reactome.org/PathwayBrowser/#/R-BTA-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Bos taurus 16516 R-BTA-5649883 https://reactome.org/PathwayBrowser/#/R-BTA-5649883 POLB-mediated DNA strand displacement synthesis IEA Bos taurus 16516 R-BTA-5655892 https://reactome.org/PathwayBrowser/#/R-BTA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Bos taurus 16516 R-BTA-5655965 https://reactome.org/PathwayBrowser/#/R-BTA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Bos taurus 16516 R-BTA-5656148 https://reactome.org/PathwayBrowser/#/R-BTA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Bos taurus 16516 R-BTA-5656158 https://reactome.org/PathwayBrowser/#/R-BTA-5656158 POLZ elongates POLI-incorporated dNMP IEA Bos taurus 16516 R-BTA-5685994 https://reactome.org/PathwayBrowser/#/R-BTA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Bos taurus 16516 R-BTA-5687360 https://reactome.org/PathwayBrowser/#/R-BTA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Bos taurus 16516 R-BTA-5687464 https://reactome.org/PathwayBrowser/#/R-BTA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Bos taurus 16516 R-BTA-5687640 https://reactome.org/PathwayBrowser/#/R-BTA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Bos taurus 16516 R-BTA-5691001 https://reactome.org/PathwayBrowser/#/R-BTA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Bos taurus 16516 R-BTA-5693593 https://reactome.org/PathwayBrowser/#/R-BTA-5693593 D-loop extension by DNA polymerases IEA Bos taurus 16516 R-BTA-5693608 https://reactome.org/PathwayBrowser/#/R-BTA-5693608 Initial resection of double-strand break ends IEA Bos taurus 16516 R-BTA-6782208 https://reactome.org/PathwayBrowser/#/R-BTA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Bos taurus 16516 R-BTA-6786166 https://reactome.org/PathwayBrowser/#/R-BTA-6786166 Translesion synthesis across unhooked ICL by POLN IEA Bos taurus 16516 R-BTA-73932 https://reactome.org/PathwayBrowser/#/R-BTA-73932 Resynthesis of excised residue by POLB IEA Bos taurus 16516 R-CEL-110319 https://reactome.org/PathwayBrowser/#/R-CEL-110319 Elongation by POLH IEA Caenorhabditis elegans 16516 R-CEL-110368 https://reactome.org/PathwayBrowser/#/R-CEL-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Caenorhabditis elegans 16516 R-CEL-5655892 https://reactome.org/PathwayBrowser/#/R-CEL-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Caenorhabditis elegans 16516 R-CEL-5656148 https://reactome.org/PathwayBrowser/#/R-CEL-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Caenorhabditis elegans 16516 R-CEL-5687464 https://reactome.org/PathwayBrowser/#/R-CEL-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Caenorhabditis elegans 16516 R-CEL-5691001 https://reactome.org/PathwayBrowser/#/R-CEL-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Caenorhabditis elegans 16516 R-CEL-6782208 https://reactome.org/PathwayBrowser/#/R-CEL-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Caenorhabditis elegans 16516 R-CFA-110311 https://reactome.org/PathwayBrowser/#/R-CFA-110311 POLZ extends translesion synthesis IEA Canis familiaris 16516 R-CFA-110319 https://reactome.org/PathwayBrowser/#/R-CFA-110319 Elongation by POLH IEA Canis familiaris 16516 R-CFA-110368 https://reactome.org/PathwayBrowser/#/R-CFA-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Canis familiaris 16516 R-CFA-111253 https://reactome.org/PathwayBrowser/#/R-CFA-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Canis familiaris 16516 R-CFA-5649723 https://reactome.org/PathwayBrowser/#/R-CFA-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Canis familiaris 16516 R-CFA-5649883 https://reactome.org/PathwayBrowser/#/R-CFA-5649883 POLB-mediated DNA strand displacement synthesis IEA Canis familiaris 16516 R-CFA-5655892 https://reactome.org/PathwayBrowser/#/R-CFA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Canis familiaris 16516 R-CFA-5655965 https://reactome.org/PathwayBrowser/#/R-CFA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Canis familiaris 16516 R-CFA-5656148 https://reactome.org/PathwayBrowser/#/R-CFA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Canis familiaris 16516 R-CFA-5656158 https://reactome.org/PathwayBrowser/#/R-CFA-5656158 POLZ elongates POLI-incorporated dNMP IEA Canis familiaris 16516 R-CFA-5685994 https://reactome.org/PathwayBrowser/#/R-CFA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Canis familiaris 16516 R-CFA-5687360 https://reactome.org/PathwayBrowser/#/R-CFA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Canis familiaris 16516 R-CFA-5687464 https://reactome.org/PathwayBrowser/#/R-CFA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Canis familiaris 16516 R-CFA-5687640 https://reactome.org/PathwayBrowser/#/R-CFA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Canis familiaris 16516 R-CFA-5691001 https://reactome.org/PathwayBrowser/#/R-CFA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Canis familiaris 16516 R-CFA-5693593 https://reactome.org/PathwayBrowser/#/R-CFA-5693593 D-loop extension by DNA polymerases IEA Canis familiaris 16516 R-CFA-5693608 https://reactome.org/PathwayBrowser/#/R-CFA-5693608 Initial resection of double-strand break ends IEA Canis familiaris 16516 R-CFA-6782208 https://reactome.org/PathwayBrowser/#/R-CFA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Canis familiaris 16516 R-CFA-6786166 https://reactome.org/PathwayBrowser/#/R-CFA-6786166 Translesion synthesis across unhooked ICL by POLN IEA Canis familiaris 16516 R-CFA-73932 https://reactome.org/PathwayBrowser/#/R-CFA-73932 Resynthesis of excised residue by POLB IEA Canis familiaris 16516 R-DDI-110368 https://reactome.org/PathwayBrowser/#/R-DDI-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Dictyostelium discoideum 16516 R-DDI-111253 https://reactome.org/PathwayBrowser/#/R-DDI-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Dictyostelium discoideum 16516 R-DDI-5649723 https://reactome.org/PathwayBrowser/#/R-DDI-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Dictyostelium discoideum 16516 R-DDI-5649883 https://reactome.org/PathwayBrowser/#/R-DDI-5649883 POLB-mediated DNA strand displacement synthesis IEA Dictyostelium discoideum 16516 R-DDI-5655892 https://reactome.org/PathwayBrowser/#/R-DDI-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Dictyostelium discoideum 16516 R-DDI-5687360 https://reactome.org/PathwayBrowser/#/R-DDI-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Dictyostelium discoideum 16516 R-DDI-5691001 https://reactome.org/PathwayBrowser/#/R-DDI-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Dictyostelium discoideum 16516 R-DDI-6782208 https://reactome.org/PathwayBrowser/#/R-DDI-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Dictyostelium discoideum 16516 R-DDI-73932 https://reactome.org/PathwayBrowser/#/R-DDI-73932 Resynthesis of excised residue by POLB IEA Dictyostelium discoideum 16516 R-DME-110311 https://reactome.org/PathwayBrowser/#/R-DME-110311 POLZ extends translesion synthesis IEA Drosophila melanogaster 16516 R-DME-110319 https://reactome.org/PathwayBrowser/#/R-DME-110319 Elongation by POLH IEA Drosophila melanogaster 16516 R-DME-110368 https://reactome.org/PathwayBrowser/#/R-DME-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Drosophila melanogaster 16516 R-DME-5655892 https://reactome.org/PathwayBrowser/#/R-DME-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Drosophila melanogaster 16516 R-DME-5655965 https://reactome.org/PathwayBrowser/#/R-DME-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Drosophila melanogaster 16516 R-DME-5656148 https://reactome.org/PathwayBrowser/#/R-DME-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Drosophila melanogaster 16516 R-DME-5656158 https://reactome.org/PathwayBrowser/#/R-DME-5656158 POLZ elongates POLI-incorporated dNMP IEA Drosophila melanogaster 16516 R-DME-5687464 https://reactome.org/PathwayBrowser/#/R-DME-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Drosophila melanogaster 16516 R-DME-5687640 https://reactome.org/PathwayBrowser/#/R-DME-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Drosophila melanogaster 16516 R-DME-5691001 https://reactome.org/PathwayBrowser/#/R-DME-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Drosophila melanogaster 16516 R-DME-6782208 https://reactome.org/PathwayBrowser/#/R-DME-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Drosophila melanogaster 16516 R-DRE-110319 https://reactome.org/PathwayBrowser/#/R-DRE-110319 Elongation by POLH IEA Danio rerio 16516 R-DRE-111253 https://reactome.org/PathwayBrowser/#/R-DRE-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Danio rerio 16516 R-DRE-5649723 https://reactome.org/PathwayBrowser/#/R-DRE-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Danio rerio 16516 R-DRE-5649883 https://reactome.org/PathwayBrowser/#/R-DRE-5649883 POLB-mediated DNA strand displacement synthesis IEA Danio rerio 16516 R-DRE-5656148 https://reactome.org/PathwayBrowser/#/R-DRE-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Danio rerio 16516 R-GGA-110311 https://reactome.org/PathwayBrowser/#/R-GGA-110311 POLZ extends translesion synthesis IEA Gallus gallus 16516 R-GGA-110319 https://reactome.org/PathwayBrowser/#/R-GGA-110319 Elongation by POLH IEA Gallus gallus 16516 R-GGA-353273 https://reactome.org/PathwayBrowser/#/R-GGA-353273 Elongation by Pol zeta complex TAS Gallus gallus 16516 R-GGA-353526 https://reactome.org/PathwayBrowser/#/R-GGA-353526 Repair of ~27-30 bp long patch by DNA Pol Epsilon IEA Gallus gallus 16516 R-GGA-5655892 https://reactome.org/PathwayBrowser/#/R-GGA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Gallus gallus 16516 R-GGA-5655965 https://reactome.org/PathwayBrowser/#/R-GGA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Gallus gallus 16516 R-GGA-5656148 https://reactome.org/PathwayBrowser/#/R-GGA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Gallus gallus 16516 R-GGA-5656158 https://reactome.org/PathwayBrowser/#/R-GGA-5656158 POLZ elongates POLI-incorporated dNMP IEA Gallus gallus 16516 R-GGA-5685994 https://reactome.org/PathwayBrowser/#/R-GGA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Gallus gallus 16516 R-GGA-5687360 https://reactome.org/PathwayBrowser/#/R-GGA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Gallus gallus 16516 R-GGA-5687464 https://reactome.org/PathwayBrowser/#/R-GGA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Gallus gallus 16516 R-GGA-5687640 https://reactome.org/PathwayBrowser/#/R-GGA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Gallus gallus 16516 R-GGA-5691001 https://reactome.org/PathwayBrowser/#/R-GGA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Gallus gallus 16516 R-GGA-5693593 https://reactome.org/PathwayBrowser/#/R-GGA-5693593 D-loop extension by DNA polymerases IEA Gallus gallus 16516 R-GGA-5693608 https://reactome.org/PathwayBrowser/#/R-GGA-5693608 Initial resection of double-strand break ends IEA Gallus gallus 16516 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus 16516 R-HSA-110311 https://reactome.org/PathwayBrowser/#/R-HSA-110311 POLZ extends translesion synthesis TAS Homo sapiens 16516 R-HSA-110319 https://reactome.org/PathwayBrowser/#/R-HSA-110319 Elongation by POLH TAS Homo sapiens 16516 R-HSA-110368 https://reactome.org/PathwayBrowser/#/R-HSA-110368 POLD,POLE-mediated DNA strand displacement synthesis TAS Homo sapiens 16516 R-HSA-111253 https://reactome.org/PathwayBrowser/#/R-HSA-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site TAS Homo sapiens 16516 R-HSA-164504 https://reactome.org/PathwayBrowser/#/R-HSA-164504 Synthesis of minus strand strong stop DNA (-sssDNA) TAS Homo sapiens 16516 R-HSA-5649723 https://reactome.org/PathwayBrowser/#/R-HSA-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution TAS Homo sapiens 16516 R-HSA-5649883 https://reactome.org/PathwayBrowser/#/R-HSA-5649883 POLB-mediated DNA strand displacement synthesis TAS Homo sapiens 16516 R-HSA-5653840 https://reactome.org/PathwayBrowser/#/R-HSA-5653840 POLD,POLE complete replication of damaged DNA after TLS TAS Homo sapiens 16516 R-HSA-5655892 https://reactome.org/PathwayBrowser/#/R-HSA-5655892 POLK incorporates dNMP opposite to damaged DNA base TAS Homo sapiens 16516 R-HSA-5655965 https://reactome.org/PathwayBrowser/#/R-HSA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini TAS Homo sapiens 16516 R-HSA-5656148 https://reactome.org/PathwayBrowser/#/R-HSA-5656148 POLI incorporates dNMP opposite to damaged DNA base TAS Homo sapiens 16516 R-HSA-5656158 https://reactome.org/PathwayBrowser/#/R-HSA-5656158 POLZ elongates POLI-incorporated dNMP TAS Homo sapiens 16516 R-HSA-5685994 https://reactome.org/PathwayBrowser/#/R-HSA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 TAS Homo sapiens 16516 R-HSA-5687360 https://reactome.org/PathwayBrowser/#/R-HSA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps TAS Homo sapiens 16516 R-HSA-5687464 https://reactome.org/PathwayBrowser/#/R-HSA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ TAS Homo sapiens 16516 R-HSA-5687640 https://reactome.org/PathwayBrowser/#/R-HSA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ TAS Homo sapiens 16516 R-HSA-5691001 https://reactome.org/PathwayBrowser/#/R-HSA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER TAS Homo sapiens 16516 R-HSA-5693593 https://reactome.org/PathwayBrowser/#/R-HSA-5693593 D-loop extension by DNA polymerases TAS Homo sapiens 16516 R-HSA-5693608 https://reactome.org/PathwayBrowser/#/R-HSA-5693608 Initial resection of double-strand break ends TAS Homo sapiens 16516 R-HSA-6782208 https://reactome.org/PathwayBrowser/#/R-HSA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER TAS Homo sapiens 16516 R-HSA-6786166 https://reactome.org/PathwayBrowser/#/R-HSA-6786166 Translesion synthesis across unhooked ICL by POLN TAS Homo sapiens 16516 R-HSA-73932 https://reactome.org/PathwayBrowser/#/R-HSA-73932 Resynthesis of excised residue by POLB TAS Homo sapiens 16516 R-HSA-9624033 https://reactome.org/PathwayBrowser/#/R-HSA-9624033 Initiation of HCMV DNA Replication TAS Homo sapiens 16516 R-MMU-110311 https://reactome.org/PathwayBrowser/#/R-MMU-110311 POLZ extends translesion synthesis IEA Mus musculus 16516 R-MMU-110319 https://reactome.org/PathwayBrowser/#/R-MMU-110319 Elongation by POLH IEA Mus musculus 16516 R-MMU-110368 https://reactome.org/PathwayBrowser/#/R-MMU-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Mus musculus 16516 R-MMU-111253 https://reactome.org/PathwayBrowser/#/R-MMU-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Mus musculus 16516 R-MMU-5649723 https://reactome.org/PathwayBrowser/#/R-MMU-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Mus musculus 16516 R-MMU-5649883 https://reactome.org/PathwayBrowser/#/R-MMU-5649883 POLB-mediated DNA strand displacement synthesis IEA Mus musculus 16516 R-MMU-5655892 https://reactome.org/PathwayBrowser/#/R-MMU-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Mus musculus 16516 R-MMU-5655965 https://reactome.org/PathwayBrowser/#/R-MMU-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Mus musculus 16516 R-MMU-5656148 https://reactome.org/PathwayBrowser/#/R-MMU-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Mus musculus 16516 R-MMU-5656158 https://reactome.org/PathwayBrowser/#/R-MMU-5656158 POLZ elongates POLI-incorporated dNMP IEA Mus musculus 16516 R-MMU-5685994 https://reactome.org/PathwayBrowser/#/R-MMU-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Mus musculus 16516 R-MMU-5687360 https://reactome.org/PathwayBrowser/#/R-MMU-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Mus musculus 16516 R-MMU-5687464 https://reactome.org/PathwayBrowser/#/R-MMU-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Mus musculus 16516 R-MMU-5687640 https://reactome.org/PathwayBrowser/#/R-MMU-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Mus musculus 16516 R-MMU-5691001 https://reactome.org/PathwayBrowser/#/R-MMU-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Mus musculus 16516 R-MMU-5693593 https://reactome.org/PathwayBrowser/#/R-MMU-5693593 D-loop extension by DNA polymerases IEA Mus musculus 16516 R-MMU-5693608 https://reactome.org/PathwayBrowser/#/R-MMU-5693608 Initial resection of double-strand break ends IEA Mus musculus 16516 R-MMU-6782208 https://reactome.org/PathwayBrowser/#/R-MMU-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Mus musculus 16516 R-MMU-6786166 https://reactome.org/PathwayBrowser/#/R-MMU-6786166 Translesion synthesis across unhooked ICL by POLN IEA Mus musculus 16516 R-MMU-73932 https://reactome.org/PathwayBrowser/#/R-MMU-73932 Resynthesis of excised residue by POLB IEA Mus musculus 16516 R-PFA-110311 https://reactome.org/PathwayBrowser/#/R-PFA-110311 POLZ extends translesion synthesis IEA Plasmodium falciparum 16516 R-PFA-110319 https://reactome.org/PathwayBrowser/#/R-PFA-110319 Elongation by POLH IEA Plasmodium falciparum 16516 R-PFA-110368 https://reactome.org/PathwayBrowser/#/R-PFA-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Plasmodium falciparum 16516 R-PFA-5655892 https://reactome.org/PathwayBrowser/#/R-PFA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Plasmodium falciparum 16516 R-PFA-5655965 https://reactome.org/PathwayBrowser/#/R-PFA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Plasmodium falciparum 16516 R-PFA-5656148 https://reactome.org/PathwayBrowser/#/R-PFA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Plasmodium falciparum 16516 R-PFA-5656158 https://reactome.org/PathwayBrowser/#/R-PFA-5656158 POLZ elongates POLI-incorporated dNMP IEA Plasmodium falciparum 16516 R-PFA-5691001 https://reactome.org/PathwayBrowser/#/R-PFA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Plasmodium falciparum 16516 R-PFA-6782208 https://reactome.org/PathwayBrowser/#/R-PFA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Plasmodium falciparum 16516 R-RNO-110311 https://reactome.org/PathwayBrowser/#/R-RNO-110311 POLZ extends translesion synthesis IEA Rattus norvegicus 16516 R-RNO-110319 https://reactome.org/PathwayBrowser/#/R-RNO-110319 Elongation by POLH IEA Rattus norvegicus 16516 R-RNO-110368 https://reactome.org/PathwayBrowser/#/R-RNO-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Rattus norvegicus 16516 R-RNO-111253 https://reactome.org/PathwayBrowser/#/R-RNO-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Rattus norvegicus 16516 R-RNO-5649723 https://reactome.org/PathwayBrowser/#/R-RNO-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Rattus norvegicus 16516 R-RNO-5649883 https://reactome.org/PathwayBrowser/#/R-RNO-5649883 POLB-mediated DNA strand displacement synthesis IEA Rattus norvegicus 16516 R-RNO-5655892 https://reactome.org/PathwayBrowser/#/R-RNO-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Rattus norvegicus 16516 R-RNO-5655965 https://reactome.org/PathwayBrowser/#/R-RNO-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Rattus norvegicus 16516 R-RNO-5656148 https://reactome.org/PathwayBrowser/#/R-RNO-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Rattus norvegicus 16516 R-RNO-5656158 https://reactome.org/PathwayBrowser/#/R-RNO-5656158 POLZ elongates POLI-incorporated dNMP IEA Rattus norvegicus 16516 R-RNO-5685994 https://reactome.org/PathwayBrowser/#/R-RNO-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Rattus norvegicus 16516 R-RNO-5687360 https://reactome.org/PathwayBrowser/#/R-RNO-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Rattus norvegicus 16516 R-RNO-5687464 https://reactome.org/PathwayBrowser/#/R-RNO-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Rattus norvegicus 16516 R-RNO-5687640 https://reactome.org/PathwayBrowser/#/R-RNO-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Rattus norvegicus 16516 R-RNO-5691001 https://reactome.org/PathwayBrowser/#/R-RNO-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Rattus norvegicus 16516 R-RNO-5693593 https://reactome.org/PathwayBrowser/#/R-RNO-5693593 D-loop extension by DNA polymerases IEA Rattus norvegicus 16516 R-RNO-5693608 https://reactome.org/PathwayBrowser/#/R-RNO-5693608 Initial resection of double-strand break ends IEA Rattus norvegicus 16516 R-RNO-6782208 https://reactome.org/PathwayBrowser/#/R-RNO-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Rattus norvegicus 16516 R-RNO-6786166 https://reactome.org/PathwayBrowser/#/R-RNO-6786166 Translesion synthesis across unhooked ICL by POLN IEA Rattus norvegicus 16516 R-RNO-73932 https://reactome.org/PathwayBrowser/#/R-RNO-73932 Resynthesis of excised residue by POLB IEA Rattus norvegicus 16516 R-SCE-110311 https://reactome.org/PathwayBrowser/#/R-SCE-110311 POLZ extends translesion synthesis IEA Saccharomyces cerevisiae 16516 R-SCE-110319 https://reactome.org/PathwayBrowser/#/R-SCE-110319 Elongation by POLH IEA Saccharomyces cerevisiae 16516 R-SCE-5655892 https://reactome.org/PathwayBrowser/#/R-SCE-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Saccharomyces cerevisiae 16516 R-SCE-5655965 https://reactome.org/PathwayBrowser/#/R-SCE-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Saccharomyces cerevisiae 16516 R-SCE-5656148 https://reactome.org/PathwayBrowser/#/R-SCE-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Saccharomyces cerevisiae 16516 R-SCE-5656158 https://reactome.org/PathwayBrowser/#/R-SCE-5656158 POLZ elongates POLI-incorporated dNMP IEA Saccharomyces cerevisiae 16516 R-SCE-5691001 https://reactome.org/PathwayBrowser/#/R-SCE-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Saccharomyces cerevisiae 16516 R-SCE-6782208 https://reactome.org/PathwayBrowser/#/R-SCE-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Saccharomyces cerevisiae 16516 R-SPO-110311 https://reactome.org/PathwayBrowser/#/R-SPO-110311 POLZ extends translesion synthesis IEA Schizosaccharomyces pombe 16516 R-SPO-110319 https://reactome.org/PathwayBrowser/#/R-SPO-110319 Elongation by POLH IEA Schizosaccharomyces pombe 16516 R-SPO-110368 https://reactome.org/PathwayBrowser/#/R-SPO-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Schizosaccharomyces pombe 16516 R-SPO-5655892 https://reactome.org/PathwayBrowser/#/R-SPO-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Schizosaccharomyces pombe 16516 R-SPO-5655965 https://reactome.org/PathwayBrowser/#/R-SPO-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Schizosaccharomyces pombe 16516 R-SPO-5656148 https://reactome.org/PathwayBrowser/#/R-SPO-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Schizosaccharomyces pombe 16516 R-SPO-5656158 https://reactome.org/PathwayBrowser/#/R-SPO-5656158 POLZ elongates POLI-incorporated dNMP IEA Schizosaccharomyces pombe 16516 R-SPO-5687464 https://reactome.org/PathwayBrowser/#/R-SPO-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Schizosaccharomyces pombe 16516 R-SPO-5691001 https://reactome.org/PathwayBrowser/#/R-SPO-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Schizosaccharomyces pombe 16516 R-SPO-6782208 https://reactome.org/PathwayBrowser/#/R-SPO-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Schizosaccharomyces pombe 16516 R-SSC-110311 https://reactome.org/PathwayBrowser/#/R-SSC-110311 POLZ extends translesion synthesis IEA Sus scrofa 16516 R-SSC-110319 https://reactome.org/PathwayBrowser/#/R-SSC-110319 Elongation by POLH IEA Sus scrofa 16516 R-SSC-110368 https://reactome.org/PathwayBrowser/#/R-SSC-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Sus scrofa 16516 R-SSC-111253 https://reactome.org/PathwayBrowser/#/R-SSC-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Sus scrofa 16516 R-SSC-5649723 https://reactome.org/PathwayBrowser/#/R-SSC-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Sus scrofa 16516 R-SSC-5649883 https://reactome.org/PathwayBrowser/#/R-SSC-5649883 POLB-mediated DNA strand displacement synthesis IEA Sus scrofa 16516 R-SSC-5655892 https://reactome.org/PathwayBrowser/#/R-SSC-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Sus scrofa 16516 R-SSC-5655965 https://reactome.org/PathwayBrowser/#/R-SSC-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Sus scrofa 16516 R-SSC-5656148 https://reactome.org/PathwayBrowser/#/R-SSC-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Sus scrofa 16516 R-SSC-5656158 https://reactome.org/PathwayBrowser/#/R-SSC-5656158 POLZ elongates POLI-incorporated dNMP IEA Sus scrofa 16516 R-SSC-5685994 https://reactome.org/PathwayBrowser/#/R-SSC-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Sus scrofa 16516 R-SSC-5687360 https://reactome.org/PathwayBrowser/#/R-SSC-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Sus scrofa 16516 R-SSC-5687464 https://reactome.org/PathwayBrowser/#/R-SSC-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Sus scrofa 16516 R-SSC-5687640 https://reactome.org/PathwayBrowser/#/R-SSC-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Sus scrofa 16516 R-SSC-5691001 https://reactome.org/PathwayBrowser/#/R-SSC-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Sus scrofa 16516 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa 16516 R-SSC-5693608 https://reactome.org/PathwayBrowser/#/R-SSC-5693608 Initial resection of double-strand break ends IEA Sus scrofa 16516 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa 16516 R-SSC-6786166 https://reactome.org/PathwayBrowser/#/R-SSC-6786166 Translesion synthesis across unhooked ICL by POLN IEA Sus scrofa 16516 R-SSC-73932 https://reactome.org/PathwayBrowser/#/R-SSC-73932 Resynthesis of excised residue by POLB IEA Sus scrofa 16516 R-XTR-110311 https://reactome.org/PathwayBrowser/#/R-XTR-110311 POLZ extends translesion synthesis IEA Xenopus tropicalis 16516 R-XTR-110319 https://reactome.org/PathwayBrowser/#/R-XTR-110319 Elongation by POLH IEA Xenopus tropicalis 16516 R-XTR-110368 https://reactome.org/PathwayBrowser/#/R-XTR-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Xenopus tropicalis 16516 R-XTR-111253 https://reactome.org/PathwayBrowser/#/R-XTR-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Xenopus tropicalis 16516 R-XTR-5649723 https://reactome.org/PathwayBrowser/#/R-XTR-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Xenopus tropicalis 16516 R-XTR-5649883 https://reactome.org/PathwayBrowser/#/R-XTR-5649883 POLB-mediated DNA strand displacement synthesis IEA Xenopus tropicalis 16516 R-XTR-5655892 https://reactome.org/PathwayBrowser/#/R-XTR-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Xenopus tropicalis 16516 R-XTR-5655965 https://reactome.org/PathwayBrowser/#/R-XTR-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Xenopus tropicalis 16516 R-XTR-5656148 https://reactome.org/PathwayBrowser/#/R-XTR-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Xenopus tropicalis 16516 R-XTR-5656158 https://reactome.org/PathwayBrowser/#/R-XTR-5656158 POLZ elongates POLI-incorporated dNMP IEA Xenopus tropicalis 16516 R-XTR-5687360 https://reactome.org/PathwayBrowser/#/R-XTR-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Xenopus tropicalis 16516 R-XTR-5691001 https://reactome.org/PathwayBrowser/#/R-XTR-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Xenopus tropicalis 16516 R-XTR-6782208 https://reactome.org/PathwayBrowser/#/R-XTR-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Xenopus tropicalis 16516 R-XTR-73932 https://reactome.org/PathwayBrowser/#/R-XTR-73932 Resynthesis of excised residue by POLB IEA Xenopus tropicalis 16518 R-BTA-5690565 https://reactome.org/PathwayBrowser/#/R-BTA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Bos taurus 16518 R-BTA-8847579 https://reactome.org/PathwayBrowser/#/R-BTA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Bos taurus 16518 R-CEL-5690565 https://reactome.org/PathwayBrowser/#/R-CEL-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 16518 R-CEL-8847579 https://reactome.org/PathwayBrowser/#/R-CEL-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 16518 R-CFA-5690565 https://reactome.org/PathwayBrowser/#/R-CFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Canis familiaris 16518 R-CFA-8847579 https://reactome.org/PathwayBrowser/#/R-CFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Canis familiaris 16518 R-DDI-5690565 https://reactome.org/PathwayBrowser/#/R-DDI-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 16518 R-DDI-8847579 https://reactome.org/PathwayBrowser/#/R-DDI-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 16518 R-DME-5690565 https://reactome.org/PathwayBrowser/#/R-DME-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 16518 R-DME-8847579 https://reactome.org/PathwayBrowser/#/R-DME-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 16518 R-DRE-5690565 https://reactome.org/PathwayBrowser/#/R-DRE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Danio rerio 16518 R-GGA-5690565 https://reactome.org/PathwayBrowser/#/R-GGA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Gallus gallus 16518 R-GGA-8847579 https://reactome.org/PathwayBrowser/#/R-GGA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Gallus gallus 16518 R-HSA-5690565 https://reactome.org/PathwayBrowser/#/R-HSA-5690565 SCD desaturates ST-CoA to OLE-CoA TAS Homo sapiens 16518 R-HSA-8847579 https://reactome.org/PathwayBrowser/#/R-HSA-8847579 SCD5 desaturates ST-CoA to OLE-CoA TAS Homo sapiens 16518 R-MMU-5690565 https://reactome.org/PathwayBrowser/#/R-MMU-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Mus musculus 16518 R-PFA-5690565 https://reactome.org/PathwayBrowser/#/R-PFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 16518 R-PFA-8847579 https://reactome.org/PathwayBrowser/#/R-PFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 16518 R-RNO-5690565 https://reactome.org/PathwayBrowser/#/R-RNO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Rattus norvegicus 16518 R-SCE-5690565 https://reactome.org/PathwayBrowser/#/R-SCE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 16518 R-SCE-8847579 https://reactome.org/PathwayBrowser/#/R-SCE-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 16518 R-SPO-5690565 https://reactome.org/PathwayBrowser/#/R-SPO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 16518 R-SPO-8847579 https://reactome.org/PathwayBrowser/#/R-SPO-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 16518 R-SSC-5690565 https://reactome.org/PathwayBrowser/#/R-SSC-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Sus scrofa 16518 R-SSC-8847579 https://reactome.org/PathwayBrowser/#/R-SSC-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Sus scrofa 16518 R-XTR-5690565 https://reactome.org/PathwayBrowser/#/R-XTR-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Xenopus tropicalis 16521 R-BTA-191366 https://reactome.org/PathwayBrowser/#/R-BTA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Bos taurus 16521 R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 16521 R-BTA-9755937 https://reactome.org/PathwayBrowser/#/R-BTA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Bos taurus 16521 R-CEL-9755937 https://reactome.org/PathwayBrowser/#/R-CEL-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Caenorhabditis elegans 16521 R-CFA-191366 https://reactome.org/PathwayBrowser/#/R-CFA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Canis familiaris 16521 R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 16521 R-CFA-9755937 https://reactome.org/PathwayBrowser/#/R-CFA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Canis familiaris 16521 R-DDI-191366 https://reactome.org/PathwayBrowser/#/R-DDI-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Dictyostelium discoideum 16521 R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 16521 R-DRE-191366 https://reactome.org/PathwayBrowser/#/R-DRE-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Danio rerio 16521 R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 16521 R-DRE-9755937 https://reactome.org/PathwayBrowser/#/R-DRE-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Danio rerio 16521 R-GGA-191366 https://reactome.org/PathwayBrowser/#/R-GGA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Gallus gallus 16521 R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 16521 R-GGA-9755937 https://reactome.org/PathwayBrowser/#/R-GGA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Gallus gallus 16521 R-HSA-191366 https://reactome.org/PathwayBrowser/#/R-HSA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol TAS Homo sapiens 16521 R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 16521 R-HSA-9755937 https://reactome.org/PathwayBrowser/#/R-HSA-9755937 DHCR24 reduces LAN to 24,25-dhLAN TAS Homo sapiens 16521 R-MMU-191366 https://reactome.org/PathwayBrowser/#/R-MMU-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Mus musculus 16521 R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 16521 R-MMU-9755937 https://reactome.org/PathwayBrowser/#/R-MMU-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Mus musculus 16521 R-RNO-191366 https://reactome.org/PathwayBrowser/#/R-RNO-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Rattus norvegicus 16521 R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 16521 R-RNO-9755937 https://reactome.org/PathwayBrowser/#/R-RNO-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Rattus norvegicus 16521 R-SCE-191366 https://reactome.org/PathwayBrowser/#/R-SCE-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Saccharomyces cerevisiae 16521 R-SCE-194678 https://reactome.org/PathwayBrowser/#/R-SCE-194678 CYP51A1 demethylates LNSOL IEA Saccharomyces cerevisiae 16521 R-SPO-191366 https://reactome.org/PathwayBrowser/#/R-SPO-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Schizosaccharomyces pombe 16521 R-SPO-194678 https://reactome.org/PathwayBrowser/#/R-SPO-194678 CYP51A1 demethylates LNSOL IEA Schizosaccharomyces pombe 16521 R-SSC-191366 https://reactome.org/PathwayBrowser/#/R-SSC-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Sus scrofa 16521 R-SSC-194678 https://reactome.org/PathwayBrowser/#/R-SSC-194678 CYP51A1 demethylates LNSOL IEA Sus scrofa 16521 R-SSC-9755937 https://reactome.org/PathwayBrowser/#/R-SSC-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Sus scrofa 16521 R-XTR-191366 https://reactome.org/PathwayBrowser/#/R-XTR-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Xenopus tropicalis 16521 R-XTR-9755937 https://reactome.org/PathwayBrowser/#/R-XTR-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Xenopus tropicalis 16523 R-BTA-376200 https://reactome.org/PathwayBrowser/#/R-BTA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Bos taurus 16523 R-BTA-432164 https://reactome.org/PathwayBrowser/#/R-BTA-432164 Ca2+ influx into the post-synaptic cell IEA Bos taurus 16523 R-BTA-438037 https://reactome.org/PathwayBrowser/#/R-BTA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Bos taurus 16523 R-BTA-5672965 https://reactome.org/PathwayBrowser/#/R-BTA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Bos taurus 16523 R-BTA-9014741 https://reactome.org/PathwayBrowser/#/R-BTA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Bos taurus 16523 R-BTA-9014766 https://reactome.org/PathwayBrowser/#/R-BTA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Bos taurus 16523 R-CEL-432164 https://reactome.org/PathwayBrowser/#/R-CEL-432164 Ca2+ influx into the post-synaptic cell IEA Caenorhabditis elegans 16523 R-CEL-438037 https://reactome.org/PathwayBrowser/#/R-CEL-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Caenorhabditis elegans 16523 R-CEL-9014741 https://reactome.org/PathwayBrowser/#/R-CEL-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Caenorhabditis elegans 16523 R-CEL-9014766 https://reactome.org/PathwayBrowser/#/R-CEL-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Caenorhabditis elegans 16523 R-CFA-376200 https://reactome.org/PathwayBrowser/#/R-CFA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Canis familiaris 16523 R-CFA-432164 https://reactome.org/PathwayBrowser/#/R-CFA-432164 Ca2+ influx into the post-synaptic cell IEA Canis familiaris 16523 R-CFA-438037 https://reactome.org/PathwayBrowser/#/R-CFA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Canis familiaris 16523 R-CFA-5672965 https://reactome.org/PathwayBrowser/#/R-CFA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Canis familiaris 16523 R-CFA-9014741 https://reactome.org/PathwayBrowser/#/R-CFA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Canis familiaris 16523 R-CFA-9014766 https://reactome.org/PathwayBrowser/#/R-CFA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Canis familiaris 16523 R-DDI-9014741 https://reactome.org/PathwayBrowser/#/R-DDI-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Dictyostelium discoideum 16523 R-DDI-9014766 https://reactome.org/PathwayBrowser/#/R-DDI-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Dictyostelium discoideum 16523 R-DME-376200 https://reactome.org/PathwayBrowser/#/R-DME-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Drosophila melanogaster 16523 R-DME-432164 https://reactome.org/PathwayBrowser/#/R-DME-432164 Ca2+ influx into the post-synaptic cell IEA Drosophila melanogaster 16523 R-DME-438037 https://reactome.org/PathwayBrowser/#/R-DME-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Drosophila melanogaster 16523 R-DRE-432164 https://reactome.org/PathwayBrowser/#/R-DRE-432164 Ca2+ influx into the post-synaptic cell IEA Danio rerio 16523 R-GGA-432164 https://reactome.org/PathwayBrowser/#/R-GGA-432164 Ca2+ influx into the post-synaptic cell IEA Gallus gallus 16523 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus 16523 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus 16523 R-GGA-9014741 https://reactome.org/PathwayBrowser/#/R-GGA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Gallus gallus 16523 R-GGA-9014766 https://reactome.org/PathwayBrowser/#/R-GGA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Gallus gallus 16523 R-HSA-376200 https://reactome.org/PathwayBrowser/#/R-HSA-376200 SLC7A10-mediated uptake of small neutral amino acids TAS Homo sapiens 16523 R-HSA-432162 https://reactome.org/PathwayBrowser/#/R-HSA-432162 Unblocking of GRIN1:GRIN2 NMDA receptors IEA Homo sapiens 16523 R-HSA-432164 https://reactome.org/PathwayBrowser/#/R-HSA-432164 Ca2+ influx into the post-synaptic cell TAS Homo sapiens 16523 R-HSA-432172 https://reactome.org/PathwayBrowser/#/R-HSA-432172 Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor IEA Homo sapiens 16523 R-HSA-438037 https://reactome.org/PathwayBrowser/#/R-HSA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors TAS Homo sapiens 16523 R-HSA-442732 https://reactome.org/PathwayBrowser/#/R-HSA-442732 NMDA-activated RASGRF1 activates RAS IEA Homo sapiens 16523 R-HSA-442760 https://reactome.org/PathwayBrowser/#/R-HSA-442760 Activation of RasGRF IEA Homo sapiens 16523 R-HSA-445367 https://reactome.org/PathwayBrowser/#/R-HSA-445367 CaMKII binds activated NMDA receptor IEA Homo sapiens 16523 R-HSA-5672965 https://reactome.org/PathwayBrowser/#/R-HSA-5672965 RAS GEFs promote RAS nucleotide exchange TAS Homo sapiens 16523 R-HSA-9014741 https://reactome.org/PathwayBrowser/#/R-HSA-9014741 PXLP-K56-SRR dimer deaminates D-Ser TAS Homo sapiens 16523 R-HSA-9014766 https://reactome.org/PathwayBrowser/#/R-HSA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser TAS Homo sapiens 16523 R-HSA-9612085 https://reactome.org/PathwayBrowser/#/R-HSA-9612085 SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs IEA Homo sapiens 16523 R-HSA-9617326 https://reactome.org/PathwayBrowser/#/R-HSA-9617326 CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 IEA Homo sapiens 16523 R-HSA-9618750 https://reactome.org/PathwayBrowser/#/R-HSA-9618750 CaMKII phosphorylates AMPA receptor IEA Homo sapiens 16523 R-MMU-376200 https://reactome.org/PathwayBrowser/#/R-MMU-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Mus musculus 16523 R-MMU-432164 https://reactome.org/PathwayBrowser/#/R-MMU-432164 Ca2+ influx into the post-synaptic cell IEA Mus musculus 16523 R-MMU-438037 https://reactome.org/PathwayBrowser/#/R-MMU-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Mus musculus 16523 R-MMU-5672965 https://reactome.org/PathwayBrowser/#/R-MMU-5672965 RAS GEFs promote RAS nucleotide exchange IEA Mus musculus 16523 R-MMU-9014741 https://reactome.org/PathwayBrowser/#/R-MMU-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Mus musculus 16523 R-MMU-9014766 https://reactome.org/PathwayBrowser/#/R-MMU-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Mus musculus 16523 R-RNO-376200 https://reactome.org/PathwayBrowser/#/R-RNO-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Rattus norvegicus 16523 R-RNO-432164 https://reactome.org/PathwayBrowser/#/R-RNO-432164 Ca2+ influx into the post-synaptic cell IEA Rattus norvegicus 16523 R-RNO-438037 https://reactome.org/PathwayBrowser/#/R-RNO-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Rattus norvegicus 16523 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus 16523 R-RNO-9014741 https://reactome.org/PathwayBrowser/#/R-RNO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Rattus norvegicus 16523 R-RNO-9014766 https://reactome.org/PathwayBrowser/#/R-RNO-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Rattus norvegicus 16523 R-SCE-9014741 https://reactome.org/PathwayBrowser/#/R-SCE-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Saccharomyces cerevisiae 16523 R-SCE-9014766 https://reactome.org/PathwayBrowser/#/R-SCE-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Saccharomyces cerevisiae 16523 R-SPO-9014741 https://reactome.org/PathwayBrowser/#/R-SPO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Schizosaccharomyces pombe 16523 R-SPO-9014766 https://reactome.org/PathwayBrowser/#/R-SPO-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Schizosaccharomyces pombe 16523 R-SSC-376200 https://reactome.org/PathwayBrowser/#/R-SSC-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Sus scrofa 16523 R-SSC-432164 https://reactome.org/PathwayBrowser/#/R-SSC-432164 Ca2+ influx into the post-synaptic cell IEA Sus scrofa 16523 R-SSC-438037 https://reactome.org/PathwayBrowser/#/R-SSC-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Sus scrofa 16523 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa 16523 R-SSC-9014741 https://reactome.org/PathwayBrowser/#/R-SSC-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Sus scrofa 16523 R-SSC-9014766 https://reactome.org/PathwayBrowser/#/R-SSC-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Sus scrofa 16523 R-XTR-376200 https://reactome.org/PathwayBrowser/#/R-XTR-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Xenopus tropicalis 16523 R-XTR-432164 https://reactome.org/PathwayBrowser/#/R-XTR-432164 Ca2+ influx into the post-synaptic cell IEA Xenopus tropicalis 16523 R-XTR-9014741 https://reactome.org/PathwayBrowser/#/R-XTR-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Xenopus tropicalis 16523 R-XTR-9014766 https://reactome.org/PathwayBrowser/#/R-XTR-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Xenopus tropicalis 16525 R-BTA-193362 https://reactome.org/PathwayBrowser/#/R-BTA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Bos taurus 16525 R-BTA-194121 https://reactome.org/PathwayBrowser/#/R-BTA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Bos taurus 16525 R-BTA-194130 https://reactome.org/PathwayBrowser/#/R-BTA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Bos taurus 16525 R-BTA-194153 https://reactome.org/PathwayBrowser/#/R-BTA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Bos taurus 16525 R-BTA-194187 https://reactome.org/PathwayBrowser/#/R-BTA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Bos taurus 16525 R-BTA-9733964 https://reactome.org/PathwayBrowser/#/R-BTA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Bos taurus 16525 R-BTA-9733969 https://reactome.org/PathwayBrowser/#/R-BTA-9733969 Bile salts dissociate from FABP6 IEA Bos taurus 16525 R-BTA-9733973 https://reactome.org/PathwayBrowser/#/R-BTA-9733973 Bile salts bind FABP6 IEA Bos taurus 16525 R-CEL-159431 https://reactome.org/PathwayBrowser/#/R-CEL-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Caenorhabditis elegans 16525 R-CEL-193491 https://reactome.org/PathwayBrowser/#/R-CEL-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Caenorhabditis elegans 16525 R-CEL-194121 https://reactome.org/PathwayBrowser/#/R-CEL-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 16525 R-CEL-194130 https://reactome.org/PathwayBrowser/#/R-CEL-194130 Transport (influx) of bile salts and acids by OATP-A IEA Caenorhabditis elegans 16525 R-CEL-194153 https://reactome.org/PathwayBrowser/#/R-CEL-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Caenorhabditis elegans 16525 R-CEL-194187 https://reactome.org/PathwayBrowser/#/R-CEL-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 16525 R-CEL-9733969 https://reactome.org/PathwayBrowser/#/R-CEL-9733969 Bile salts dissociate from FABP6 IEA Caenorhabditis elegans 16525 R-CEL-9733973 https://reactome.org/PathwayBrowser/#/R-CEL-9733973 Bile salts bind FABP6 IEA Caenorhabditis elegans 16525 R-CFA-159431 https://reactome.org/PathwayBrowser/#/R-CFA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Canis familiaris 16525 R-CFA-193362 https://reactome.org/PathwayBrowser/#/R-CFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Canis familiaris 16525 R-CFA-193491 https://reactome.org/PathwayBrowser/#/R-CFA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Canis familiaris 16525 R-CFA-194121 https://reactome.org/PathwayBrowser/#/R-CFA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Canis familiaris 16525 R-CFA-194130 https://reactome.org/PathwayBrowser/#/R-CFA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Canis familiaris 16525 R-CFA-194153 https://reactome.org/PathwayBrowser/#/R-CFA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Canis familiaris 16525 R-CFA-194187 https://reactome.org/PathwayBrowser/#/R-CFA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Canis familiaris 16525 R-CFA-9733964 https://reactome.org/PathwayBrowser/#/R-CFA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Canis familiaris 16525 R-DDI-193362 https://reactome.org/PathwayBrowser/#/R-DDI-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 16525 R-DDI-194153 https://reactome.org/PathwayBrowser/#/R-DDI-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 16525 R-DME-194121 https://reactome.org/PathwayBrowser/#/R-DME-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 16525 R-DME-194130 https://reactome.org/PathwayBrowser/#/R-DME-194130 Transport (influx) of bile salts and acids by OATP-A IEA Drosophila melanogaster 16525 R-DME-194153 https://reactome.org/PathwayBrowser/#/R-DME-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Drosophila melanogaster 16525 R-DME-194187 https://reactome.org/PathwayBrowser/#/R-DME-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 16525 R-DME-9733969 https://reactome.org/PathwayBrowser/#/R-DME-9733969 Bile salts dissociate from FABP6 IEA Drosophila melanogaster 16525 R-DME-9733973 https://reactome.org/PathwayBrowser/#/R-DME-9733973 Bile salts bind FABP6 IEA Drosophila melanogaster 16525 R-DRE-194121 https://reactome.org/PathwayBrowser/#/R-DRE-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Danio rerio 16525 R-DRE-194130 https://reactome.org/PathwayBrowser/#/R-DRE-194130 Transport (influx) of bile salts and acids by OATP-A IEA Danio rerio 16525 R-DRE-194187 https://reactome.org/PathwayBrowser/#/R-DRE-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Danio rerio 16525 R-DRE-9733969 https://reactome.org/PathwayBrowser/#/R-DRE-9733969 Bile salts dissociate from FABP6 IEA Danio rerio 16525 R-DRE-9733973 https://reactome.org/PathwayBrowser/#/R-DRE-9733973 Bile salts bind FABP6 IEA Danio rerio 16525 R-GGA-159431 https://reactome.org/PathwayBrowser/#/R-GGA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Gallus gallus 16525 R-GGA-193362 https://reactome.org/PathwayBrowser/#/R-GGA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Gallus gallus 16525 R-GGA-193491 https://reactome.org/PathwayBrowser/#/R-GGA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Gallus gallus 16525 R-GGA-194130 https://reactome.org/PathwayBrowser/#/R-GGA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Gallus gallus 16525 R-GGA-194153 https://reactome.org/PathwayBrowser/#/R-GGA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Gallus gallus 16525 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus 16525 R-GGA-9733964 https://reactome.org/PathwayBrowser/#/R-GGA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Gallus gallus 16525 R-GGA-9733969 https://reactome.org/PathwayBrowser/#/R-GGA-9733969 Bile salts dissociate from FABP6 IEA Gallus gallus 16525 R-GGA-9733973 https://reactome.org/PathwayBrowser/#/R-GGA-9733973 Bile salts bind FABP6 IEA Gallus gallus 16525 R-HSA-159431 https://reactome.org/PathwayBrowser/#/R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine TAS Homo sapiens 16525 R-HSA-192315 https://reactome.org/PathwayBrowser/#/R-HSA-192315 Bile salts are translocated from the peroxisomal matrix to the cytosol TAS Homo sapiens 16525 R-HSA-193362 https://reactome.org/PathwayBrowser/#/R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region TAS Homo sapiens 16525 R-HSA-193491 https://reactome.org/PathwayBrowser/#/R-HSA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate TAS Homo sapiens 16525 R-HSA-194121 https://reactome.org/PathwayBrowser/#/R-HSA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol TAS Homo sapiens 16525 R-HSA-194130 https://reactome.org/PathwayBrowser/#/R-HSA-194130 Transport (influx) of bile salts and acids by OATP-A TAS Homo sapiens 16525 R-HSA-194153 https://reactome.org/PathwayBrowser/#/R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region TAS Homo sapiens 16525 R-HSA-194187 https://reactome.org/PathwayBrowser/#/R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol TAS Homo sapiens 16525 R-HSA-5678517 https://reactome.org/PathwayBrowser/#/R-HSA-5678517 Defective ABCB11 does not transport bile salts from cytosol to extracellular region TAS Homo sapiens 16525 R-HSA-9733964 https://reactome.org/PathwayBrowser/#/R-HSA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region TAS Homo sapiens 16525 R-HSA-9733969 https://reactome.org/PathwayBrowser/#/R-HSA-9733969 Bile salts dissociate from FABP6 TAS Homo sapiens 16525 R-HSA-9733973 https://reactome.org/PathwayBrowser/#/R-HSA-9733973 Bile salts bind FABP6 TAS Homo sapiens 16525 R-MMU-159431 https://reactome.org/PathwayBrowser/#/R-MMU-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Mus musculus 16525 R-MMU-193362 https://reactome.org/PathwayBrowser/#/R-MMU-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Mus musculus 16525 R-MMU-193491 https://reactome.org/PathwayBrowser/#/R-MMU-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Mus musculus 16525 R-MMU-194121 https://reactome.org/PathwayBrowser/#/R-MMU-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Mus musculus 16525 R-MMU-194130 https://reactome.org/PathwayBrowser/#/R-MMU-194130 Transport (influx) of bile salts and acids by OATP-A IEA Mus musculus 16525 R-MMU-194153 https://reactome.org/PathwayBrowser/#/R-MMU-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Mus musculus 16525 R-MMU-194187 https://reactome.org/PathwayBrowser/#/R-MMU-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Mus musculus 16525 R-MMU-9733964 https://reactome.org/PathwayBrowser/#/R-MMU-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Mus musculus 16525 R-MMU-9733969 https://reactome.org/PathwayBrowser/#/R-MMU-9733969 Bile salts dissociate from FABP6 IEA Mus musculus 16525 R-MMU-9733973 https://reactome.org/PathwayBrowser/#/R-MMU-9733973 Bile salts bind FABP6 IEA Mus musculus 16525 R-PFA-193362 https://reactome.org/PathwayBrowser/#/R-PFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Plasmodium falciparum 16525 R-RNO-159431 https://reactome.org/PathwayBrowser/#/R-RNO-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Rattus norvegicus 16525 R-RNO-193362 https://reactome.org/PathwayBrowser/#/R-RNO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 16525 R-RNO-193491 https://reactome.org/PathwayBrowser/#/R-RNO-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Rattus norvegicus 16525 R-RNO-194121 https://reactome.org/PathwayBrowser/#/R-RNO-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Rattus norvegicus 16525 R-RNO-194130 https://reactome.org/PathwayBrowser/#/R-RNO-194130 Transport (influx) of bile salts and acids by OATP-A IEA Rattus norvegicus 16525 R-RNO-194153 https://reactome.org/PathwayBrowser/#/R-RNO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 16525 R-RNO-194187 https://reactome.org/PathwayBrowser/#/R-RNO-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Rattus norvegicus 16525 R-RNO-9733964 https://reactome.org/PathwayBrowser/#/R-RNO-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 16525 R-RNO-9733969 https://reactome.org/PathwayBrowser/#/R-RNO-9733969 Bile salts dissociate from FABP6 IEA Rattus norvegicus 16525 R-RNO-9733973 https://reactome.org/PathwayBrowser/#/R-RNO-9733973 Bile salts bind FABP6 IEA Rattus norvegicus 16525 R-SCE-194153 https://reactome.org/PathwayBrowser/#/R-SCE-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Saccharomyces cerevisiae 16525 R-SPO-193362 https://reactome.org/PathwayBrowser/#/R-SPO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 16525 R-SPO-194153 https://reactome.org/PathwayBrowser/#/R-SPO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 16525 R-SSC-159431 https://reactome.org/PathwayBrowser/#/R-SSC-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Sus scrofa 16525 R-SSC-193362 https://reactome.org/PathwayBrowser/#/R-SSC-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Sus scrofa 16525 R-SSC-193491 https://reactome.org/PathwayBrowser/#/R-SSC-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Sus scrofa 16525 R-SSC-194121 https://reactome.org/PathwayBrowser/#/R-SSC-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Sus scrofa 16525 R-SSC-194130 https://reactome.org/PathwayBrowser/#/R-SSC-194130 Transport (influx) of bile salts and acids by OATP-A IEA Sus scrofa 16525 R-SSC-194153 https://reactome.org/PathwayBrowser/#/R-SSC-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Sus scrofa 16525 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa 16525 R-SSC-9733964 https://reactome.org/PathwayBrowser/#/R-SSC-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Sus scrofa 16525 R-SSC-9733969 https://reactome.org/PathwayBrowser/#/R-SSC-9733969 Bile salts dissociate from FABP6 IEA Sus scrofa 16525 R-SSC-9733973 https://reactome.org/PathwayBrowser/#/R-SSC-9733973 Bile salts bind FABP6 IEA Sus scrofa 16525 R-XTR-159431 https://reactome.org/PathwayBrowser/#/R-XTR-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Xenopus tropicalis 16525 R-XTR-193491 https://reactome.org/PathwayBrowser/#/R-XTR-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Xenopus tropicalis 16525 R-XTR-194121 https://reactome.org/PathwayBrowser/#/R-XTR-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 16525 R-XTR-194153 https://reactome.org/PathwayBrowser/#/R-XTR-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 16525 R-XTR-194187 https://reactome.org/PathwayBrowser/#/R-XTR-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 16525 R-XTR-9733964 https://reactome.org/PathwayBrowser/#/R-XTR-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 16525 R-XTR-9733969 https://reactome.org/PathwayBrowser/#/R-XTR-9733969 Bile salts dissociate from FABP6 IEA Xenopus tropicalis 16525 R-XTR-9733973 https://reactome.org/PathwayBrowser/#/R-XTR-9733973 Bile salts bind FABP6 IEA Xenopus tropicalis 16526 R-BTA-1234164 https://reactome.org/PathwayBrowser/#/R-BTA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Bos taurus 16526 R-BTA-1234165 https://reactome.org/PathwayBrowser/#/R-BTA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Bos taurus 16526 R-BTA-1234173 https://reactome.org/PathwayBrowser/#/R-BTA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Bos taurus 16526 R-BTA-1234177 https://reactome.org/PathwayBrowser/#/R-BTA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Bos taurus 16526 R-BTA-1234181 https://reactome.org/PathwayBrowser/#/R-BTA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Bos taurus 16526 R-BTA-1237042 https://reactome.org/PathwayBrowser/#/R-BTA-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Bos taurus 16526 R-BTA-1237045 https://reactome.org/PathwayBrowser/#/R-BTA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Bos taurus 16526 R-BTA-1237047 https://reactome.org/PathwayBrowser/#/R-BTA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Bos taurus 16526 R-BTA-1237059 https://reactome.org/PathwayBrowser/#/R-BTA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Bos taurus 16526 R-BTA-1237069 https://reactome.org/PathwayBrowser/#/R-BTA-1237069 RHAG transports CO2 from extracellular region to cytosol IEA Bos taurus 16526 R-BTA-1237081 https://reactome.org/PathwayBrowser/#/R-BTA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Bos taurus 16526 R-BTA-1237325 https://reactome.org/PathwayBrowser/#/R-BTA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Bos taurus 16526 R-BTA-1247645 https://reactome.org/PathwayBrowser/#/R-BTA-1247645 RHAG transports CO2 from cytosol to extracellular region IEA Bos taurus 16526 R-BTA-1247649 https://reactome.org/PathwayBrowser/#/R-BTA-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Bos taurus 16526 R-BTA-1247668 https://reactome.org/PathwayBrowser/#/R-BTA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Bos taurus 16526 R-BTA-1475017 https://reactome.org/PathwayBrowser/#/R-BTA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Bos taurus 16526 R-BTA-1475022 https://reactome.org/PathwayBrowser/#/R-BTA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Bos taurus 16526 R-BTA-1475025 https://reactome.org/PathwayBrowser/#/R-BTA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Bos taurus 16526 R-BTA-1475026 https://reactome.org/PathwayBrowser/#/R-BTA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Bos taurus 16526 R-BTA-1475028 https://reactome.org/PathwayBrowser/#/R-BTA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Bos taurus 16526 R-BTA-1475032 https://reactome.org/PathwayBrowser/#/R-BTA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Bos taurus 16526 R-BTA-1475435 https://reactome.org/PathwayBrowser/#/R-BTA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Bos taurus 16526 R-BTA-1475436 https://reactome.org/PathwayBrowser/#/R-BTA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Bos taurus 16526 R-BTA-159752 https://reactome.org/PathwayBrowser/#/R-BTA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Bos taurus 16526 R-BTA-159761 https://reactome.org/PathwayBrowser/#/R-BTA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Bos taurus 16526 R-BTA-159795 https://reactome.org/PathwayBrowser/#/R-BTA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Bos taurus 16526 R-BTA-159803 https://reactome.org/PathwayBrowser/#/R-BTA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Bos taurus 16526 R-BTA-159819 https://reactome.org/PathwayBrowser/#/R-BTA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Bos taurus 16526 R-BTA-159826 https://reactome.org/PathwayBrowser/#/R-BTA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Bos taurus 16526 R-BTA-163820 https://reactome.org/PathwayBrowser/#/R-BTA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Bos taurus 16526 R-BTA-1650808 https://reactome.org/PathwayBrowser/#/R-BTA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Bos taurus 16526 R-BTA-189421 https://reactome.org/PathwayBrowser/#/R-BTA-189421 CPO transforms COPRO3 to PPGEN9 IEA Bos taurus 16526 R-BTA-189425 https://reactome.org/PathwayBrowser/#/R-BTA-189425 UROD decarboxylates URO3 to COPRO3 IEA Bos taurus 16526 R-BTA-189442 https://reactome.org/PathwayBrowser/#/R-BTA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Bos taurus 16526 R-BTA-190182 https://reactome.org/PathwayBrowser/#/R-BTA-190182 UROD decarboxylates URO1 to COPRO1 IEA Bos taurus 16526 R-BTA-191414 https://reactome.org/PathwayBrowser/#/R-BTA-191414 MVD decarboxylates MVA5PP to IPPP IEA Bos taurus 16526 R-BTA-194642 https://reactome.org/PathwayBrowser/#/R-BTA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Bos taurus 16526 R-BTA-194718 https://reactome.org/PathwayBrowser/#/R-BTA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Bos taurus 16526 R-BTA-196840 https://reactome.org/PathwayBrowser/#/R-BTA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Bos taurus 16526 R-BTA-197268 https://reactome.org/PathwayBrowser/#/R-BTA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Bos taurus 16526 R-BTA-1980233 https://reactome.org/PathwayBrowser/#/R-BTA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Bos taurus 16526 R-BTA-1981104 https://reactome.org/PathwayBrowser/#/R-BTA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Bos taurus 16526 R-BTA-2046083 https://reactome.org/PathwayBrowser/#/R-BTA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Bos taurus 16526 R-BTA-2046088 https://reactome.org/PathwayBrowser/#/R-BTA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Bos taurus 16526 R-BTA-2046090 https://reactome.org/PathwayBrowser/#/R-BTA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 16526 R-BTA-2046094 https://reactome.org/PathwayBrowser/#/R-BTA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Bos taurus 16526 R-BTA-2046095 https://reactome.org/PathwayBrowser/#/R-BTA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Bos taurus 16526 R-BTA-2046100 https://reactome.org/PathwayBrowser/#/R-BTA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Bos taurus 16526 R-BTA-209859 https://reactome.org/PathwayBrowser/#/R-BTA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Bos taurus 16526 R-BTA-209924 https://reactome.org/PathwayBrowser/#/R-BTA-209924 Dopa is decarboxylated to dopamine IEA Bos taurus 16526 R-BTA-2172678 https://reactome.org/PathwayBrowser/#/R-BTA-2172678 PHF8 demethylates histone H4K20me1 IEA Bos taurus 16526 R-BTA-350598 https://reactome.org/PathwayBrowser/#/R-BTA-350598 Arginine<=>Agmatine+CO2 IEA Bos taurus 16526 R-BTA-351222 https://reactome.org/PathwayBrowser/#/R-BTA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Bos taurus 16526 R-BTA-372819 https://reactome.org/PathwayBrowser/#/R-BTA-372819 PCK2 phosphorylates OA to yield PEP IEA Bos taurus 16526 R-BTA-389540 https://reactome.org/PathwayBrowser/#/R-BTA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 16526 R-BTA-389550 https://reactome.org/PathwayBrowser/#/R-BTA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 16526 R-BTA-389639 https://reactome.org/PathwayBrowser/#/R-BTA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Bos taurus 16526 R-BTA-428127 https://reactome.org/PathwayBrowser/#/R-BTA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Bos taurus 16526 R-BTA-450984 https://reactome.org/PathwayBrowser/#/R-BTA-450984 IDH2 dimer decarboxylates isocitrate IEA Bos taurus 16526 R-BTA-4722133 https://reactome.org/PathwayBrowser/#/R-BTA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Bos taurus 16526 R-BTA-4724279 https://reactome.org/PathwayBrowser/#/R-BTA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Bos taurus 16526 R-BTA-4724284 https://reactome.org/PathwayBrowser/#/R-BTA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Bos taurus 16526 R-BTA-4754176 https://reactome.org/PathwayBrowser/#/R-BTA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Bos taurus 16526 R-BTA-4754181 https://reactome.org/PathwayBrowser/#/R-BTA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Bos taurus 16526 R-BTA-4754187 https://reactome.org/PathwayBrowser/#/R-BTA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Bos taurus 16526 R-BTA-5423117 https://reactome.org/PathwayBrowser/#/R-BTA-5423117 PHF8 demethylates MeK21-histone H4 IEA Bos taurus 16526 R-BTA-548800 https://reactome.org/PathwayBrowser/#/R-BTA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Bos taurus 16526 R-BTA-548814 https://reactome.org/PathwayBrowser/#/R-BTA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Bos taurus 16526 R-BTA-548815 https://reactome.org/PathwayBrowser/#/R-BTA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Bos taurus 16526 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 16526 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 16526 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 16526 R-BTA-5661114 https://reactome.org/PathwayBrowser/#/R-BTA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Bos taurus 16526 R-BTA-5661115 https://reactome.org/PathwayBrowser/#/R-BTA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Bos taurus 16526 R-BTA-5661116 https://reactome.org/PathwayBrowser/#/R-BTA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Bos taurus 16526 R-BTA-5661120 https://reactome.org/PathwayBrowser/#/R-BTA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Bos taurus 16526 R-BTA-5661121 https://reactome.org/PathwayBrowser/#/R-BTA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Bos taurus 16526 R-BTA-5661122 https://reactome.org/PathwayBrowser/#/R-BTA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Bos taurus 16526 R-BTA-5661124 https://reactome.org/PathwayBrowser/#/R-BTA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Bos taurus 16526 R-BTA-5661125 https://reactome.org/PathwayBrowser/#/R-BTA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Bos taurus 16526 R-BTA-5693967 https://reactome.org/PathwayBrowser/#/R-BTA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Bos taurus 16526 R-BTA-6787757 https://reactome.org/PathwayBrowser/#/R-BTA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Bos taurus 16526 R-BTA-6807214 https://reactome.org/PathwayBrowser/#/R-BTA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Bos taurus 16526 R-BTA-6808487 https://reactome.org/PathwayBrowser/#/R-BTA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 16526 R-BTA-6808496 https://reactome.org/PathwayBrowser/#/R-BTA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 16526 R-BTA-6814165 https://reactome.org/PathwayBrowser/#/R-BTA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Bos taurus 16526 R-BTA-70241 https://reactome.org/PathwayBrowser/#/R-BTA-70241 PCK1 phosphorylates OA to yield PEP IEA Bos taurus 16526 R-BTA-70692 https://reactome.org/PathwayBrowser/#/R-BTA-70692 ornithine => putrescine + CO2 IEA Bos taurus 16526 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 16526 R-BTA-70893 https://reactome.org/PathwayBrowser/#/R-BTA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Bos taurus 16526 R-BTA-70967 https://reactome.org/PathwayBrowser/#/R-BTA-70967 IDH3 complex decarboxylates isocitrate IEA Bos taurus 16526 R-BTA-71031 https://reactome.org/PathwayBrowser/#/R-BTA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Bos taurus 16526 R-BTA-71037 https://reactome.org/PathwayBrowser/#/R-BTA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Bos taurus 16526 R-BTA-71046 https://reactome.org/PathwayBrowser/#/R-BTA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Bos taurus 16526 R-BTA-71163 https://reactome.org/PathwayBrowser/#/R-BTA-71163 HPD dioxygenates HPP IEA Bos taurus 16526 R-BTA-71241 https://reactome.org/PathwayBrowser/#/R-BTA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Bos taurus 16526 R-BTA-71261 https://reactome.org/PathwayBrowser/#/R-BTA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Bos taurus 16526 R-BTA-71299 https://reactome.org/PathwayBrowser/#/R-BTA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Bos taurus 16526 R-BTA-71401 https://reactome.org/PathwayBrowser/#/R-BTA-71401 OGDH dimer decarboxylates 2-OG IEA Bos taurus 16526 R-BTA-73564 https://reactome.org/PathwayBrowser/#/R-BTA-73564 UMPS dimer decarboxylates OMP to UMP IEA Bos taurus 16526 R-BTA-73591 https://reactome.org/PathwayBrowser/#/R-BTA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Bos taurus 16526 R-BTA-73620 https://reactome.org/PathwayBrowser/#/R-BTA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Bos taurus 16526 R-BTA-73806 https://reactome.org/PathwayBrowser/#/R-BTA-73806 AIR + CO2 => CAIR IEA Bos taurus 16526 R-BTA-75872 https://reactome.org/PathwayBrowser/#/R-BTA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Bos taurus 16526 R-BTA-8857692 https://reactome.org/PathwayBrowser/#/R-BTA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Bos taurus 16526 R-BTA-888572 https://reactome.org/PathwayBrowser/#/R-BTA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Bos taurus 16526 R-BTA-888577 https://reactome.org/PathwayBrowser/#/R-BTA-888577 Synthesis of GABA by GAD2 IEA Bos taurus 16526 R-BTA-9012016 https://reactome.org/PathwayBrowser/#/R-BTA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Bos taurus 16526 R-BTA-9012036 https://reactome.org/PathwayBrowser/#/R-BTA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Bos taurus 16526 R-BTA-9012268 https://reactome.org/PathwayBrowser/#/R-BTA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Bos taurus 16526 R-BTA-9012349 https://reactome.org/PathwayBrowser/#/R-BTA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Bos taurus 16526 R-BTA-9629578 https://reactome.org/PathwayBrowser/#/R-BTA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Bos taurus 16526 R-BTA-9629591 https://reactome.org/PathwayBrowser/#/R-BTA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Bos taurus 16526 R-BTA-9629869 https://reactome.org/PathwayBrowser/#/R-BTA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Bos taurus 16526 R-BTA-9629888 https://reactome.org/PathwayBrowser/#/R-BTA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Bos taurus 16526 R-BTA-9629946 https://reactome.org/PathwayBrowser/#/R-BTA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Bos taurus 16526 R-BTA-9630022 https://reactome.org/PathwayBrowser/#/R-BTA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Bos taurus 16526 R-BTA-9630769 https://reactome.org/PathwayBrowser/#/R-BTA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Bos taurus 16526 R-BTA-9630967 https://reactome.org/PathwayBrowser/#/R-BTA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Bos taurus 16526 R-BTA-9630993 https://reactome.org/PathwayBrowser/#/R-BTA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Bos taurus 16526 R-BTA-9631356 https://reactome.org/PathwayBrowser/#/R-BTA-9631356 ASPH:Fe2+ hydroxylates an aspartate residue of F9 TAS Bos taurus 16526 R-BTA-977301 https://reactome.org/PathwayBrowser/#/R-BTA-977301 Histidine is decarboxylated to histamine IEA Bos taurus 16526 R-BTA-977317 https://reactome.org/PathwayBrowser/#/R-BTA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Bos taurus 16526 R-BTA-9861660 https://reactome.org/PathwayBrowser/#/R-BTA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Bos taurus 16526 R-BTA-9861734 https://reactome.org/PathwayBrowser/#/R-BTA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Bos taurus 16526 R-CEL-1234165 https://reactome.org/PathwayBrowser/#/R-CEL-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 16526 R-CEL-1234173 https://reactome.org/PathwayBrowser/#/R-CEL-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 16526 R-CEL-1234177 https://reactome.org/PathwayBrowser/#/R-CEL-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 16526 R-CEL-1234181 https://reactome.org/PathwayBrowser/#/R-CEL-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 16526 R-CEL-1237045 https://reactome.org/PathwayBrowser/#/R-CEL-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Caenorhabditis elegans 16526 R-CEL-1237047 https://reactome.org/PathwayBrowser/#/R-CEL-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Caenorhabditis elegans 16526 R-CEL-1237059 https://reactome.org/PathwayBrowser/#/R-CEL-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Caenorhabditis elegans 16526 R-CEL-1237069 https://reactome.org/PathwayBrowser/#/R-CEL-1237069 RHAG transports CO2 from extracellular region to cytosol IEA Caenorhabditis elegans 16526 R-CEL-1237081 https://reactome.org/PathwayBrowser/#/R-CEL-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Caenorhabditis elegans 16526 R-CEL-1247645 https://reactome.org/PathwayBrowser/#/R-CEL-1247645 RHAG transports CO2 from cytosol to extracellular region IEA Caenorhabditis elegans 16526 R-CEL-1475017 https://reactome.org/PathwayBrowser/#/R-CEL-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Caenorhabditis elegans 16526 R-CEL-1475022 https://reactome.org/PathwayBrowser/#/R-CEL-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Caenorhabditis elegans 16526 R-CEL-1475025 https://reactome.org/PathwayBrowser/#/R-CEL-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Caenorhabditis elegans 16526 R-CEL-1475026 https://reactome.org/PathwayBrowser/#/R-CEL-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Caenorhabditis elegans 16526 R-CEL-1475028 https://reactome.org/PathwayBrowser/#/R-CEL-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Caenorhabditis elegans 16526 R-CEL-1475032 https://reactome.org/PathwayBrowser/#/R-CEL-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Caenorhabditis elegans 16526 R-CEL-1475435 https://reactome.org/PathwayBrowser/#/R-CEL-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Caenorhabditis elegans 16526 R-CEL-1475436 https://reactome.org/PathwayBrowser/#/R-CEL-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Caenorhabditis elegans 16526 R-CEL-1650808 https://reactome.org/PathwayBrowser/#/R-CEL-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Caenorhabditis elegans 16526 R-CEL-191414 https://reactome.org/PathwayBrowser/#/R-CEL-191414 MVD decarboxylates MVA5PP to IPPP IEA Caenorhabditis elegans 16526 R-CEL-194642 https://reactome.org/PathwayBrowser/#/R-CEL-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Caenorhabditis elegans 16526 R-CEL-194718 https://reactome.org/PathwayBrowser/#/R-CEL-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Caenorhabditis elegans 16526 R-CEL-196840 https://reactome.org/PathwayBrowser/#/R-CEL-196840 3xPPCDC:3FMN decarboxylates PPC IEA Caenorhabditis elegans 16526 R-CEL-1981104 https://reactome.org/PathwayBrowser/#/R-CEL-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Caenorhabditis elegans 16526 R-CEL-2046088 https://reactome.org/PathwayBrowser/#/R-CEL-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Caenorhabditis elegans 16526 R-CEL-2046094 https://reactome.org/PathwayBrowser/#/R-CEL-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Caenorhabditis elegans 16526 R-CEL-209859 https://reactome.org/PathwayBrowser/#/R-CEL-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Caenorhabditis elegans 16526 R-CEL-209924 https://reactome.org/PathwayBrowser/#/R-CEL-209924 Dopa is decarboxylated to dopamine IEA Caenorhabditis elegans 16526 R-CEL-2172678 https://reactome.org/PathwayBrowser/#/R-CEL-2172678 PHF8 demethylates histone H4K20me1 IEA Caenorhabditis elegans 16526 R-CEL-350598 https://reactome.org/PathwayBrowser/#/R-CEL-350598 Arginine<=>Agmatine+CO2 IEA Caenorhabditis elegans 16526 R-CEL-351222 https://reactome.org/PathwayBrowser/#/R-CEL-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Caenorhabditis elegans 16526 R-CEL-372819 https://reactome.org/PathwayBrowser/#/R-CEL-372819 PCK2 phosphorylates OA to yield PEP IEA Caenorhabditis elegans 16526 R-CEL-389540 https://reactome.org/PathwayBrowser/#/R-CEL-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 16526 R-CEL-389550 https://reactome.org/PathwayBrowser/#/R-CEL-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 16526 R-CEL-389639 https://reactome.org/PathwayBrowser/#/R-CEL-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Caenorhabditis elegans 16526 R-CEL-450984 https://reactome.org/PathwayBrowser/#/R-CEL-450984 IDH2 dimer decarboxylates isocitrate IEA Caenorhabditis elegans 16526 R-CEL-4722133 https://reactome.org/PathwayBrowser/#/R-CEL-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-4724279 https://reactome.org/PathwayBrowser/#/R-CEL-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-4724284 https://reactome.org/PathwayBrowser/#/R-CEL-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-4754176 https://reactome.org/PathwayBrowser/#/R-CEL-4754176 JMJD6 demethylates MeR3-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-4754181 https://reactome.org/PathwayBrowser/#/R-CEL-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-4754187 https://reactome.org/PathwayBrowser/#/R-CEL-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-5423117 https://reactome.org/PathwayBrowser/#/R-CEL-5423117 PHF8 demethylates MeK21-histone H4 IEA Caenorhabditis elegans 16526 R-CEL-548800 https://reactome.org/PathwayBrowser/#/R-CEL-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Caenorhabditis elegans 16526 R-CEL-548814 https://reactome.org/PathwayBrowser/#/R-CEL-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Caenorhabditis elegans 16526 R-CEL-5661114 https://reactome.org/PathwayBrowser/#/R-CEL-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-5661115 https://reactome.org/PathwayBrowser/#/R-CEL-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-5661116 https://reactome.org/PathwayBrowser/#/R-CEL-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-5661120 https://reactome.org/PathwayBrowser/#/R-CEL-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-5661121 https://reactome.org/PathwayBrowser/#/R-CEL-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-5661122 https://reactome.org/PathwayBrowser/#/R-CEL-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Caenorhabditis elegans 16526 R-CEL-5661124 https://reactome.org/PathwayBrowser/#/R-CEL-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Caenorhabditis elegans 16526 R-CEL-5661125 https://reactome.org/PathwayBrowser/#/R-CEL-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Caenorhabditis elegans 16526 R-CEL-5693967 https://reactome.org/PathwayBrowser/#/R-CEL-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Caenorhabditis elegans 16526 R-CEL-6808487 https://reactome.org/PathwayBrowser/#/R-CEL-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 16526 R-CEL-6808496 https://reactome.org/PathwayBrowser/#/R-CEL-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 16526 R-CEL-70241 https://reactome.org/PathwayBrowser/#/R-CEL-70241 PCK1 phosphorylates OA to yield PEP IEA Caenorhabditis elegans 16526 R-CEL-70692 https://reactome.org/PathwayBrowser/#/R-CEL-70692 ornithine => putrescine + CO2 IEA Caenorhabditis elegans 16526 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 16526 R-CEL-70893 https://reactome.org/PathwayBrowser/#/R-CEL-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 16526 R-CEL-70967 https://reactome.org/PathwayBrowser/#/R-CEL-70967 IDH3 complex decarboxylates isocitrate IEA Caenorhabditis elegans 16526 R-CEL-71031 https://reactome.org/PathwayBrowser/#/R-CEL-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Caenorhabditis elegans 16526 R-CEL-71037 https://reactome.org/PathwayBrowser/#/R-CEL-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 16526 R-CEL-71046 https://reactome.org/PathwayBrowser/#/R-CEL-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Caenorhabditis elegans 16526 R-CEL-71163 https://reactome.org/PathwayBrowser/#/R-CEL-71163 HPD dioxygenates HPP IEA Caenorhabditis elegans 16526 R-CEL-71241 https://reactome.org/PathwayBrowser/#/R-CEL-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Caenorhabditis elegans 16526 R-CEL-71261 https://reactome.org/PathwayBrowser/#/R-CEL-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Caenorhabditis elegans 16526 R-CEL-71299 https://reactome.org/PathwayBrowser/#/R-CEL-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 16526 R-CEL-71401 https://reactome.org/PathwayBrowser/#/R-CEL-71401 OGDH dimer decarboxylates 2-OG IEA Caenorhabditis elegans 16526 R-CEL-73564 https://reactome.org/PathwayBrowser/#/R-CEL-73564 UMPS dimer decarboxylates OMP to UMP IEA Caenorhabditis elegans 16526 R-CEL-73591 https://reactome.org/PathwayBrowser/#/R-CEL-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Caenorhabditis elegans 16526 R-CEL-73620 https://reactome.org/PathwayBrowser/#/R-CEL-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Caenorhabditis elegans 16526 R-CEL-73806 https://reactome.org/PathwayBrowser/#/R-CEL-73806 AIR + CO2 => CAIR IEA Caenorhabditis elegans 16526 R-CEL-75872 https://reactome.org/PathwayBrowser/#/R-CEL-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Caenorhabditis elegans 16526 R-CEL-888572 https://reactome.org/PathwayBrowser/#/R-CEL-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Caenorhabditis elegans 16526 R-CEL-888577 https://reactome.org/PathwayBrowser/#/R-CEL-888577 Synthesis of GABA by GAD2 IEA Caenorhabditis elegans 16526 R-CEL-9012016 https://reactome.org/PathwayBrowser/#/R-CEL-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Caenorhabditis elegans 16526 R-CEL-9012036 https://reactome.org/PathwayBrowser/#/R-CEL-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 16526 R-CEL-9012268 https://reactome.org/PathwayBrowser/#/R-CEL-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 16526 R-CEL-9012349 https://reactome.org/PathwayBrowser/#/R-CEL-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 16526 R-CEL-9629869 https://reactome.org/PathwayBrowser/#/R-CEL-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Caenorhabditis elegans 16526 R-CEL-9629888 https://reactome.org/PathwayBrowser/#/R-CEL-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Caenorhabditis elegans 16526 R-CEL-9629946 https://reactome.org/PathwayBrowser/#/R-CEL-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Caenorhabditis elegans 16526 R-CEL-9630022 https://reactome.org/PathwayBrowser/#/R-CEL-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Caenorhabditis elegans 16526 R-CEL-9630769 https://reactome.org/PathwayBrowser/#/R-CEL-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Caenorhabditis elegans 16526 R-CEL-9630993 https://reactome.org/PathwayBrowser/#/R-CEL-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Caenorhabditis elegans 16526 R-CEL-977317 https://reactome.org/PathwayBrowser/#/R-CEL-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Caenorhabditis elegans 16526 R-CEL-9861660 https://reactome.org/PathwayBrowser/#/R-CEL-9861660 ME1 tetramer decarboxylates OA to PYR IEA Caenorhabditis elegans 16526 R-CEL-9861734 https://reactome.org/PathwayBrowser/#/R-CEL-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Caenorhabditis elegans 16526 R-CFA-1234164 https://reactome.org/PathwayBrowser/#/R-CFA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Canis familiaris 16526 R-CFA-1234165 https://reactome.org/PathwayBrowser/#/R-CFA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 16526 R-CFA-1234173 https://reactome.org/PathwayBrowser/#/R-CFA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 16526 R-CFA-1234177 https://reactome.org/PathwayBrowser/#/R-CFA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 16526 R-CFA-1234181 https://reactome.org/PathwayBrowser/#/R-CFA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 16526 R-CFA-1237042 https://reactome.org/PathwayBrowser/#/R-CFA-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Canis familiaris 16526 R-CFA-1237045 https://reactome.org/PathwayBrowser/#/R-CFA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Canis familiaris 16526 R-CFA-1237047 https://reactome.org/PathwayBrowser/#/R-CFA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Canis familiaris 16526 R-CFA-1237059 https://reactome.org/PathwayBrowser/#/R-CFA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Canis familiaris 16526 R-CFA-1237069 https://reactome.org/PathwayBrowser/#/R-CFA-1237069 RHAG transports CO2 from extracellular region to cytosol IEA Canis familiaris 16526 R-CFA-1237081 https://reactome.org/PathwayBrowser/#/R-CFA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Canis familiaris 16526 R-CFA-1237325 https://reactome.org/PathwayBrowser/#/R-CFA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Canis familiaris 16526 R-CFA-1247645 https://reactome.org/PathwayBrowser/#/R-CFA-1247645 RHAG transports CO2 from cytosol to extracellular region IEA Canis familiaris 16526 R-CFA-1247649 https://reactome.org/PathwayBrowser/#/R-CFA-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Canis familiaris 16526 R-CFA-1247668 https://reactome.org/PathwayBrowser/#/R-CFA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Canis familiaris 16526 R-CFA-1475017 https://reactome.org/PathwayBrowser/#/R-CFA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Canis familiaris 16526 R-CFA-1475022 https://reactome.org/PathwayBrowser/#/R-CFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Canis familiaris 16526 R-CFA-1475025 https://reactome.org/PathwayBrowser/#/R-CFA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Canis familiaris 16526 R-CFA-1475026 https://reactome.org/PathwayBrowser/#/R-CFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Canis familiaris 16526 R-CFA-1475028 https://reactome.org/PathwayBrowser/#/R-CFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Canis familiaris 16526 R-CFA-1475032 https://reactome.org/PathwayBrowser/#/R-CFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Canis familiaris 16526 R-CFA-1475435 https://reactome.org/PathwayBrowser/#/R-CFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Canis familiaris 16526 R-CFA-1475436 https://reactome.org/PathwayBrowser/#/R-CFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Canis familiaris 16526 R-CFA-159752 https://reactome.org/PathwayBrowser/#/R-CFA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Canis familiaris 16526 R-CFA-159761 https://reactome.org/PathwayBrowser/#/R-CFA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Canis familiaris 16526 R-CFA-159795 https://reactome.org/PathwayBrowser/#/R-CFA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Canis familiaris 16526 R-CFA-159803 https://reactome.org/PathwayBrowser/#/R-CFA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Canis familiaris 16526 R-CFA-159819 https://reactome.org/PathwayBrowser/#/R-CFA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Canis familiaris 16526 R-CFA-159826 https://reactome.org/PathwayBrowser/#/R-CFA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Canis familiaris 16526 R-CFA-1650808 https://reactome.org/PathwayBrowser/#/R-CFA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Canis familiaris 16526 R-CFA-189421 https://reactome.org/PathwayBrowser/#/R-CFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Canis familiaris 16526 R-CFA-189425 https://reactome.org/PathwayBrowser/#/R-CFA-189425 UROD decarboxylates URO3 to COPRO3 IEA Canis familiaris 16526 R-CFA-189442 https://reactome.org/PathwayBrowser/#/R-CFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Canis familiaris 16526 R-CFA-190182 https://reactome.org/PathwayBrowser/#/R-CFA-190182 UROD decarboxylates URO1 to COPRO1 IEA Canis familiaris 16526 R-CFA-191414 https://reactome.org/PathwayBrowser/#/R-CFA-191414 MVD decarboxylates MVA5PP to IPPP IEA Canis familiaris 16526 R-CFA-194642 https://reactome.org/PathwayBrowser/#/R-CFA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Canis familiaris 16526 R-CFA-194718 https://reactome.org/PathwayBrowser/#/R-CFA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Canis familiaris 16526 R-CFA-196840 https://reactome.org/PathwayBrowser/#/R-CFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Canis familiaris 16526 R-CFA-197268 https://reactome.org/PathwayBrowser/#/R-CFA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Canis familiaris 16526 R-CFA-1980233 https://reactome.org/PathwayBrowser/#/R-CFA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Canis familiaris 16526 R-CFA-1981104 https://reactome.org/PathwayBrowser/#/R-CFA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Canis familiaris 16526 R-CFA-2046083 https://reactome.org/PathwayBrowser/#/R-CFA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Canis familiaris 16526 R-CFA-2046088 https://reactome.org/PathwayBrowser/#/R-CFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Canis familiaris 16526 R-CFA-2046090 https://reactome.org/PathwayBrowser/#/R-CFA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 16526 R-CFA-2046094 https://reactome.org/PathwayBrowser/#/R-CFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Canis familiaris 16526 R-CFA-2046095 https://reactome.org/PathwayBrowser/#/R-CFA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Canis familiaris 16526 R-CFA-2046100 https://reactome.org/PathwayBrowser/#/R-CFA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Canis familiaris 16526 R-CFA-209859 https://reactome.org/PathwayBrowser/#/R-CFA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Canis familiaris 16526 R-CFA-209924 https://reactome.org/PathwayBrowser/#/R-CFA-209924 Dopa is decarboxylated to dopamine IEA Canis familiaris 16526 R-CFA-2172678 https://reactome.org/PathwayBrowser/#/R-CFA-2172678 PHF8 demethylates histone H4K20me1 IEA Canis familiaris 16526 R-CFA-350598 https://reactome.org/PathwayBrowser/#/R-CFA-350598 Arginine<=>Agmatine+CO2 IEA Canis familiaris 16526 R-CFA-351222 https://reactome.org/PathwayBrowser/#/R-CFA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Canis familiaris 16526 R-CFA-372819 https://reactome.org/PathwayBrowser/#/R-CFA-372819 PCK2 phosphorylates OA to yield PEP IEA Canis familiaris 16526 R-CFA-389540 https://reactome.org/PathwayBrowser/#/R-CFA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 16526 R-CFA-389550 https://reactome.org/PathwayBrowser/#/R-CFA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 16526 R-CFA-389639 https://reactome.org/PathwayBrowser/#/R-CFA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Canis familiaris 16526 R-CFA-428127 https://reactome.org/PathwayBrowser/#/R-CFA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Canis familiaris 16526 R-CFA-450984 https://reactome.org/PathwayBrowser/#/R-CFA-450984 IDH2 dimer decarboxylates isocitrate IEA Canis familiaris 16526 R-CFA-4722133 https://reactome.org/PathwayBrowser/#/R-CFA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Canis familiaris 16526 R-CFA-4724279 https://reactome.org/PathwayBrowser/#/R-CFA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Canis familiaris 16526 R-CFA-4724284 https://reactome.org/PathwayBrowser/#/R-CFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Canis familiaris 16526 R-CFA-4754176 https://reactome.org/PathwayBrowser/#/R-CFA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Canis familiaris 16526 R-CFA-4754181 https://reactome.org/PathwayBrowser/#/R-CFA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Canis familiaris 16526 R-CFA-4754187 https://reactome.org/PathwayBrowser/#/R-CFA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Canis familiaris 16526 R-CFA-5423117 https://reactome.org/PathwayBrowser/#/R-CFA-5423117 PHF8 demethylates MeK21-histone H4 IEA Canis familiaris 16526 R-CFA-548800 https://reactome.org/PathwayBrowser/#/R-CFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Canis familiaris 16526 R-CFA-548814 https://reactome.org/PathwayBrowser/#/R-CFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Canis familiaris 16526 R-CFA-548815 https://reactome.org/PathwayBrowser/#/R-CFA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Canis familiaris 16526 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 16526 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 16526 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 16526 R-CFA-5661114 https://reactome.org/PathwayBrowser/#/R-CFA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Canis familiaris 16526 R-CFA-5661115 https://reactome.org/PathwayBrowser/#/R-CFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Canis familiaris 16526 R-CFA-5661116 https://reactome.org/PathwayBrowser/#/R-CFA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Canis familiaris 16526 R-CFA-5661120 https://reactome.org/PathwayBrowser/#/R-CFA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Canis familiaris 16526 R-CFA-5661121 https://reactome.org/PathwayBrowser/#/R-CFA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Canis familiaris 16526 R-CFA-5661122 https://reactome.org/PathwayBrowser/#/R-CFA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Canis familiaris 16526 R-CFA-5661124 https://reactome.org/PathwayBrowser/#/R-CFA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Canis familiaris 16526 R-CFA-5661125 https://reactome.org/PathwayBrowser/#/R-CFA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Canis familiaris 16526 R-CFA-5693967 https://reactome.org/PathwayBrowser/#/R-CFA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Canis familiaris 16526 R-CFA-6787757 https://reactome.org/PathwayBrowser/#/R-CFA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Canis familiaris 16526 R-CFA-6807214 https://reactome.org/PathwayBrowser/#/R-CFA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Canis familiaris 16526 R-CFA-6808487 https://reactome.org/PathwayBrowser/#/R-CFA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 16526 R-CFA-6808496 https://reactome.org/PathwayBrowser/#/R-CFA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 16526 R-CFA-6814165 https://reactome.org/PathwayBrowser/#/R-CFA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Canis familiaris 16526 R-CFA-70241 https://reactome.org/PathwayBrowser/#/R-CFA-70241 PCK1 phosphorylates OA to yield PEP IEA Canis familiaris 16526 R-CFA-70692 https://reactome.org/PathwayBrowser/#/R-CFA-70692 ornithine => putrescine + CO2 IEA Canis familiaris 16526 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 16526 R-CFA-70893 https://reactome.org/PathwayBrowser/#/R-CFA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Canis familiaris 16526 R-CFA-70967 https://reactome.org/PathwayBrowser/#/R-CFA-70967 IDH3 complex decarboxylates isocitrate IEA Canis familiaris 16526 R-CFA-71031 https://reactome.org/PathwayBrowser/#/R-CFA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Canis familiaris 16526 R-CFA-71037 https://reactome.org/PathwayBrowser/#/R-CFA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Canis familiaris 16526 R-CFA-71046 https://reactome.org/PathwayBrowser/#/R-CFA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Canis familiaris 16526 R-CFA-71163 https://reactome.org/PathwayBrowser/#/R-CFA-71163 HPD dioxygenates HPP IEA Canis familiaris 16526 R-CFA-71241 https://reactome.org/PathwayBrowser/#/R-CFA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Canis familiaris 16526 R-CFA-71261 https://reactome.org/PathwayBrowser/#/R-CFA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Canis familiaris 16526 R-CFA-71299 https://reactome.org/PathwayBrowser/#/R-CFA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Canis familiaris 16526 R-CFA-71401 https://reactome.org/PathwayBrowser/#/R-CFA-71401 OGDH dimer decarboxylates 2-OG IEA Canis familiaris 16526 R-CFA-73564 https://reactome.org/PathwayBrowser/#/R-CFA-73564 UMPS dimer decarboxylates OMP to UMP IEA Canis familiaris 16526 R-CFA-73591 https://reactome.org/PathwayBrowser/#/R-CFA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Canis familiaris 16526 R-CFA-73620 https://reactome.org/PathwayBrowser/#/R-CFA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Canis familiaris 16526 R-CFA-73806 https://reactome.org/PathwayBrowser/#/R-CFA-73806 AIR + CO2 => CAIR IEA Canis familiaris 16526 R-CFA-75872 https://reactome.org/PathwayBrowser/#/R-CFA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Canis familiaris 16526 R-CFA-8857692 https://reactome.org/PathwayBrowser/#/R-CFA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Canis familiaris 16526 R-CFA-888572 https://reactome.org/PathwayBrowser/#/R-CFA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Canis familiaris 16526 R-CFA-888577 https://reactome.org/PathwayBrowser/#/R-CFA-888577 Synthesis of GABA by GAD2 IEA Canis familiaris 16526 R-CFA-9012016 https://reactome.org/PathwayBrowser/#/R-CFA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Canis familiaris 16526 R-CFA-9012036 https://reactome.org/PathwayBrowser/#/R-CFA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Canis familiaris 16526 R-CFA-9012268 https://reactome.org/PathwayBrowser/#/R-CFA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Canis familiaris 16526 R-CFA-9012349 https://reactome.org/PathwayBrowser/#/R-CFA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Canis familiaris 16526 R-CFA-9629578 https://reactome.org/PathwayBrowser/#/R-CFA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Canis familiaris 16526 R-CFA-9629591 https://reactome.org/PathwayBrowser/#/R-CFA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Canis familiaris 16526 R-CFA-9629869 https://reactome.org/PathwayBrowser/#/R-CFA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Canis familiaris 16526 R-CFA-9629888 https://reactome.org/PathwayBrowser/#/R-CFA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Canis familiaris 16526 R-CFA-9629946 https://reactome.org/PathwayBrowser/#/R-CFA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Canis familiaris 16526 R-CFA-9630022 https://reactome.org/PathwayBrowser/#/R-CFA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Canis familiaris 16526 R-CFA-9630769 https://reactome.org/PathwayBrowser/#/R-CFA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Canis familiaris 16526 R-CFA-9630967 https://reactome.org/PathwayBrowser/#/R-CFA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Canis familiaris 16526 R-CFA-9630993 https://reactome.org/PathwayBrowser/#/R-CFA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Canis familiaris 16526 R-CFA-977301 https://reactome.org/PathwayBrowser/#/R-CFA-977301 Histidine is decarboxylated to histamine IEA Canis familiaris 16526 R-CFA-977317 https://reactome.org/PathwayBrowser/#/R-CFA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Canis familiaris 16526 R-CFA-9861660 https://reactome.org/PathwayBrowser/#/R-CFA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Canis familiaris 16526 R-CFA-9861734 https://reactome.org/PathwayBrowser/#/R-CFA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Canis familiaris 16526 R-DDI-1237042 https://reactome.org/PathwayBrowser/#/R-DDI-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Dictyostelium discoideum 16526 R-DDI-1237069 https://reactome.org/PathwayBrowser/#/R-DDI-1237069 RHAG transports CO2 from extracellular region to cytosol IEA Dictyostelium discoideum 16526 R-DDI-1247645 https://reactome.org/PathwayBrowser/#/R-DDI-1247645 RHAG transports CO2 from cytosol to extracellular region IEA Dictyostelium discoideum 16526 R-DDI-1247649 https://reactome.org/PathwayBrowser/#/R-DDI-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Dictyostelium discoideum 16526 R-DDI-189421 https://reactome.org/PathwayBrowser/#/R-DDI-189421 CPO transforms COPRO3 to PPGEN9 IEA Dictyostelium discoideum 16526 R-DDI-189425 https://reactome.org/PathwayBrowser/#/R-DDI-189425 UROD decarboxylates URO3 to COPRO3 IEA Dictyostelium discoideum 16526 R-DDI-189442 https://reactome.org/PathwayBrowser/#/R-DDI-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Dictyostelium discoideum 16526 R-DDI-190182 https://reactome.org/PathwayBrowser/#/R-DDI-190182 UROD decarboxylates URO1 to COPRO1 IEA Dictyostelium discoideum 16526 R-DDI-191414 https://reactome.org/PathwayBrowser/#/R-DDI-191414 MVD decarboxylates MVA5PP to IPPP IEA Dictyostelium discoideum 16526 R-DDI-194642 https://reactome.org/PathwayBrowser/#/R-DDI-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Dictyostelium discoideum 16526 R-DDI-194718 https://reactome.org/PathwayBrowser/#/R-DDI-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Dictyostelium discoideum 16526 R-DDI-196840 https://reactome.org/PathwayBrowser/#/R-DDI-196840 3xPPCDC:3FMN decarboxylates PPC IEA Dictyostelium discoideum 16526 R-DDI-197268 https://reactome.org/PathwayBrowser/#/R-DDI-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Dictyostelium discoideum 16526 R-DDI-2046083 https://reactome.org/PathwayBrowser/#/R-DDI-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Dictyostelium discoideum 16526 R-DDI-2046088 https://reactome.org/PathwayBrowser/#/R-DDI-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Dictyostelium discoideum 16526 R-DDI-2046090 https://reactome.org/PathwayBrowser/#/R-DDI-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Dictyostelium discoideum 16526 R-DDI-2046094 https://reactome.org/PathwayBrowser/#/R-DDI-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Dictyostelium discoideum 16526 R-DDI-2046095 https://reactome.org/PathwayBrowser/#/R-DDI-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Dictyostelium discoideum 16526 R-DDI-2046100 https://reactome.org/PathwayBrowser/#/R-DDI-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Dictyostelium discoideum 16526 R-DDI-2172678 https://reactome.org/PathwayBrowser/#/R-DDI-2172678 PHF8 demethylates histone H4K20me1 IEA Dictyostelium discoideum 16526 R-DDI-350598 https://reactome.org/PathwayBrowser/#/R-DDI-350598 Arginine<=>Agmatine+CO2 IEA Dictyostelium discoideum 16526 R-DDI-351222 https://reactome.org/PathwayBrowser/#/R-DDI-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Dictyostelium discoideum 16526 R-DDI-372819 https://reactome.org/PathwayBrowser/#/R-DDI-372819 PCK2 phosphorylates OA to yield PEP IEA Dictyostelium discoideum 16526 R-DDI-389540 https://reactome.org/PathwayBrowser/#/R-DDI-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 16526 R-DDI-389550 https://reactome.org/PathwayBrowser/#/R-DDI-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 16526 R-DDI-389639 https://reactome.org/PathwayBrowser/#/R-DDI-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Dictyostelium discoideum 16526 R-DDI-4754181 https://reactome.org/PathwayBrowser/#/R-DDI-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Dictyostelium discoideum 16526 R-DDI-4754187 https://reactome.org/PathwayBrowser/#/R-DDI-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Dictyostelium discoideum 16526 R-DDI-548800 https://reactome.org/PathwayBrowser/#/R-DDI-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Dictyostelium discoideum 16526 R-DDI-548814 https://reactome.org/PathwayBrowser/#/R-DDI-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Dictyostelium discoideum 16526 R-DDI-5661116 https://reactome.org/PathwayBrowser/#/R-DDI-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Dictyostelium discoideum 16526 R-DDI-5661121 https://reactome.org/PathwayBrowser/#/R-DDI-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Dictyostelium discoideum 16526 R-DDI-5693967 https://reactome.org/PathwayBrowser/#/R-DDI-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Dictyostelium discoideum 16526 R-DDI-70241 https://reactome.org/PathwayBrowser/#/R-DDI-70241 PCK1 phosphorylates OA to yield PEP IEA Dictyostelium discoideum 16526 R-DDI-70692 https://reactome.org/PathwayBrowser/#/R-DDI-70692 ornithine => putrescine + CO2 IEA Dictyostelium discoideum 16526 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 16526 R-DDI-70893 https://reactome.org/PathwayBrowser/#/R-DDI-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 16526 R-DDI-70967 https://reactome.org/PathwayBrowser/#/R-DDI-70967 IDH3 complex decarboxylates isocitrate IEA Dictyostelium discoideum 16526 R-DDI-71031 https://reactome.org/PathwayBrowser/#/R-DDI-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Dictyostelium discoideum 16526 R-DDI-71037 https://reactome.org/PathwayBrowser/#/R-DDI-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 16526 R-DDI-71046 https://reactome.org/PathwayBrowser/#/R-DDI-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Dictyostelium discoideum 16526 R-DDI-71163 https://reactome.org/PathwayBrowser/#/R-DDI-71163 HPD dioxygenates HPP IEA Dictyostelium discoideum 16526 R-DDI-71299 https://reactome.org/PathwayBrowser/#/R-DDI-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 16526 R-DDI-71401 https://reactome.org/PathwayBrowser/#/R-DDI-71401 OGDH dimer decarboxylates 2-OG IEA Dictyostelium discoideum 16526 R-DDI-73564 https://reactome.org/PathwayBrowser/#/R-DDI-73564 UMPS dimer decarboxylates OMP to UMP IEA Dictyostelium discoideum 16526 R-DDI-73591 https://reactome.org/PathwayBrowser/#/R-DDI-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Dictyostelium discoideum 16526 R-DDI-73620 https://reactome.org/PathwayBrowser/#/R-DDI-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Dictyostelium discoideum 16526 R-DDI-75872 https://reactome.org/PathwayBrowser/#/R-DDI-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Dictyostelium discoideum 16526 R-DDI-9012016 https://reactome.org/PathwayBrowser/#/R-DDI-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Dictyostelium discoideum 16526 R-DDI-9629578 https://reactome.org/PathwayBrowser/#/R-DDI-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Dictyostelium discoideum 16526 R-DDI-9629591 https://reactome.org/PathwayBrowser/#/R-DDI-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Dictyostelium discoideum 16526 R-DDI-9629869 https://reactome.org/PathwayBrowser/#/R-DDI-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Dictyostelium discoideum 16526 R-DDI-9630993 https://reactome.org/PathwayBrowser/#/R-DDI-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Dictyostelium discoideum 16526 R-DDI-977317 https://reactome.org/PathwayBrowser/#/R-DDI-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Dictyostelium discoideum 16526 R-DDI-9861734 https://reactome.org/PathwayBrowser/#/R-DDI-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Dictyostelium discoideum 16526 R-DME-1234165 https://reactome.org/PathwayBrowser/#/R-DME-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 16526 R-DME-1234173 https://reactome.org/PathwayBrowser/#/R-DME-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 16526 R-DME-1234177 https://reactome.org/PathwayBrowser/#/R-DME-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 16526 R-DME-1234181 https://reactome.org/PathwayBrowser/#/R-DME-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 16526 R-DME-1237042 https://reactome.org/PathwayBrowser/#/R-DME-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Drosophila melanogaster 16526 R-DME-1237045 https://reactome.org/PathwayBrowser/#/R-DME-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Drosophila melanogaster 16526 R-DME-1237047 https://reactome.org/PathwayBrowser/#/R-DME-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Drosophila melanogaster 16526 R-DME-1237059 https://reactome.org/PathwayBrowser/#/R-DME-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Drosophila melanogaster 16526 R-DME-1237069 https://reactome.org/PathwayBrowser/#/R-DME-1237069 RHAG transports CO2 from extracellular region to cytosol IEA Drosophila melanogaster 16526 R-DME-1237081 https://reactome.org/PathwayBrowser/#/R-DME-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Drosophila melanogaster 16526 R-DME-1247645 https://reactome.org/PathwayBrowser/#/R-DME-1247645 RHAG transports CO2 from cytosol to extracellular region IEA Drosophila melanogaster 16526 R-DME-1247649 https://reactome.org/PathwayBrowser/#/R-DME-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Drosophila melanogaster 16526 R-DME-1475017 https://reactome.org/PathwayBrowser/#/R-DME-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Drosophila melanogaster 16526 R-DME-1475022 https://reactome.org/PathwayBrowser/#/R-DME-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Drosophila melanogaster 16526 R-DME-1475025 https://reactome.org/PathwayBrowser/#/R-DME-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Drosophila melanogaster 16526 R-DME-1475026 https://reactome.org/PathwayBrowser/#/R-DME-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Drosophila melanogaster 16526 R-DME-1475028 https://reactome.org/PathwayBrowser/#/R-DME-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Drosophila melanogaster 16526 R-DME-1475032 https://reactome.org/PathwayBrowser/#/R-DME-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Drosophila melanogaster 16526 R-DME-1475435 https://reactome.org/PathwayBrowser/#/R-DME-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Drosophila melanogaster 16526 R-DME-1475436 https://reactome.org/PathwayBrowser/#/R-DME-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Drosophila melanogaster 16526 R-DME-189421 https://reactome.org/PathwayBrowser/#/R-DME-189421 CPO transforms COPRO3 to PPGEN9 IEA Drosophila melanogaster 16526 R-DME-189425 https://reactome.org/PathwayBrowser/#/R-DME-189425 UROD decarboxylates URO3 to COPRO3 IEA Drosophila melanogaster 16526 R-DME-189442 https://reactome.org/PathwayBrowser/#/R-DME-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Drosophila melanogaster 16526 R-DME-190182 https://reactome.org/PathwayBrowser/#/R-DME-190182 UROD decarboxylates URO1 to COPRO1 IEA Drosophila melanogaster 16526 R-DME-191414 https://reactome.org/PathwayBrowser/#/R-DME-191414 MVD decarboxylates MVA5PP to IPPP IEA Drosophila melanogaster 16526 R-DME-196840 https://reactome.org/PathwayBrowser/#/R-DME-196840 3xPPCDC:3FMN decarboxylates PPC IEA Drosophila melanogaster 16526 R-DME-1981104 https://reactome.org/PathwayBrowser/#/R-DME-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Drosophila melanogaster 16526 R-DME-2046083 https://reactome.org/PathwayBrowser/#/R-DME-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Drosophila melanogaster 16526 R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster 16526 R-DME-2046090 https://reactome.org/PathwayBrowser/#/R-DME-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Drosophila melanogaster 16526 R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster 16526 R-DME-2046095 https://reactome.org/PathwayBrowser/#/R-DME-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Drosophila melanogaster 16526 R-DME-2046100 https://reactome.org/PathwayBrowser/#/R-DME-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Drosophila melanogaster 16526 R-DME-209859 https://reactome.org/PathwayBrowser/#/R-DME-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Drosophila melanogaster 16526 R-DME-209924 https://reactome.org/PathwayBrowser/#/R-DME-209924 Dopa is decarboxylated to dopamine IEA Drosophila melanogaster 16526 R-DME-2172678 https://reactome.org/PathwayBrowser/#/R-DME-2172678 PHF8 demethylates histone H4K20me1 IEA Drosophila melanogaster 16526 R-DME-350598 https://reactome.org/PathwayBrowser/#/R-DME-350598 Arginine<=>Agmatine+CO2 IEA Drosophila melanogaster 16526 R-DME-351222 https://reactome.org/PathwayBrowser/#/R-DME-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Drosophila melanogaster 16526 R-DME-372819 https://reactome.org/PathwayBrowser/#/R-DME-372819 PCK2 phosphorylates OA to yield PEP IEA Drosophila melanogaster 16526 R-DME-389540 https://reactome.org/PathwayBrowser/#/R-DME-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 16526 R-DME-389550 https://reactome.org/PathwayBrowser/#/R-DME-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 16526 R-DME-428127 https://reactome.org/PathwayBrowser/#/R-DME-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Drosophila melanogaster 16526 R-DME-548800 https://reactome.org/PathwayBrowser/#/R-DME-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Drosophila melanogaster 16526 R-DME-548814 https://reactome.org/PathwayBrowser/#/R-DME-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Drosophila melanogaster 16526 R-DME-548815 https://reactome.org/PathwayBrowser/#/R-DME-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Drosophila melanogaster 16526 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 16526 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 16526 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 16526 R-DME-5661124 https://reactome.org/PathwayBrowser/#/R-DME-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Drosophila melanogaster 16526 R-DME-5661125 https://reactome.org/PathwayBrowser/#/R-DME-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Drosophila melanogaster 16526 R-DME-5693967 https://reactome.org/PathwayBrowser/#/R-DME-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Drosophila melanogaster 16526 R-DME-6787757 https://reactome.org/PathwayBrowser/#/R-DME-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Drosophila melanogaster 16526 R-DME-6808487 https://reactome.org/PathwayBrowser/#/R-DME-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 16526 R-DME-6808496 https://reactome.org/PathwayBrowser/#/R-DME-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 16526 R-DME-6814165 https://reactome.org/PathwayBrowser/#/R-DME-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Drosophila melanogaster 16526 R-DME-70241 https://reactome.org/PathwayBrowser/#/R-DME-70241 PCK1 phosphorylates OA to yield PEP IEA Drosophila melanogaster 16526 R-DME-70692 https://reactome.org/PathwayBrowser/#/R-DME-70692 ornithine => putrescine + CO2 IEA Drosophila melanogaster 16526 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 16526 R-DME-70893 https://reactome.org/PathwayBrowser/#/R-DME-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 16526 R-DME-70967 https://reactome.org/PathwayBrowser/#/R-DME-70967 IDH3 complex decarboxylates isocitrate IEA Drosophila melanogaster 16526 R-DME-71037 https://reactome.org/PathwayBrowser/#/R-DME-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 16526 R-DME-71046 https://reactome.org/PathwayBrowser/#/R-DME-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Drosophila melanogaster 16526 R-DME-71163 https://reactome.org/PathwayBrowser/#/R-DME-71163 HPD dioxygenates HPP IEA Drosophila melanogaster 16526 R-DME-71241 https://reactome.org/PathwayBrowser/#/R-DME-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Drosophila melanogaster 16526 R-DME-71261 https://reactome.org/PathwayBrowser/#/R-DME-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Drosophila melanogaster 16526 R-DME-71299 https://reactome.org/PathwayBrowser/#/R-DME-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Drosophila melanogaster 16526 R-DME-71401 https://reactome.org/PathwayBrowser/#/R-DME-71401 OGDH dimer decarboxylates 2-OG IEA Drosophila melanogaster 16526 R-DME-73564 https://reactome.org/PathwayBrowser/#/R-DME-73564 UMPS dimer decarboxylates OMP to UMP IEA Drosophila melanogaster 16526 R-DME-73591 https://reactome.org/PathwayBrowser/#/R-DME-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Drosophila melanogaster 16526 R-DME-73620 https://reactome.org/PathwayBrowser/#/R-DME-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Drosophila melanogaster 16526 R-DME-73806 https://reactome.org/PathwayBrowser/#/R-DME-73806 AIR + CO2 => CAIR IEA Drosophila melanogaster 16526 R-DME-75872 https://reactome.org/PathwayBrowser/#/R-DME-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Drosophila melanogaster 16526 R-DME-888572 https://reactome.org/PathwayBrowser/#/R-DME-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Drosophila melanogaster 16526 R-DME-888577 https://reactome.org/PathwayBrowser/#/R-DME-888577 Synthesis of GABA by GAD2 IEA Drosophila melanogaster 16526 R-DME-9012016 https://reactome.org/PathwayBrowser/#/R-DME-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Drosophila melanogaster 16526 R-DME-9012036 https://reactome.org/PathwayBrowser/#/R-DME-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 16526 R-DME-9012268 https://reactome.org/PathwayBrowser/#/R-DME-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 16526 R-DME-9012349 https://reactome.org/PathwayBrowser/#/R-DME-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 16526 R-DME-9629578 https://reactome.org/PathwayBrowser/#/R-DME-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Drosophila melanogaster 16526 R-DME-9629591 https://reactome.org/PathwayBrowser/#/R-DME-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Drosophila melanogaster 16526 R-DME-9629869 https://reactome.org/PathwayBrowser/#/R-DME-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Drosophila melanogaster 16526 R-DME-9629888 https://reactome.org/PathwayBrowser/#/R-DME-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Drosophila melanogaster 16526 R-DME-9629946 https://reactome.org/PathwayBrowser/#/R-DME-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Drosophila melanogaster 16526 R-DME-9630022 https://reactome.org/PathwayBrowser/#/R-DME-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Drosophila melanogaster 16526 R-DME-9630769 https://reactome.org/PathwayBrowser/#/R-DME-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Drosophila melanogaster 16526 R-DME-9630993 https://reactome.org/PathwayBrowser/#/R-DME-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Drosophila melanogaster 16526 R-DME-977301 https://reactome.org/PathwayBrowser/#/R-DME-977301 Histidine is decarboxylated to histamine IEA Drosophila melanogaster 16526 R-DME-9861660 https://reactome.org/PathwayBrowser/#/R-DME-9861660 ME1 tetramer decarboxylates OA to PYR IEA Drosophila melanogaster 16526 R-DME-9861734 https://reactome.org/PathwayBrowser/#/R-DME-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Drosophila melanogaster 16526 R-DRE-1234164 https://reactome.org/PathwayBrowser/#/R-DRE-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Danio rerio 16526 R-DRE-1234165 https://reactome.org/PathwayBrowser/#/R-DRE-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Danio rerio 16526 R-DRE-1234181 https://reactome.org/PathwayBrowser/#/R-DRE-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Danio rerio 16526 R-DRE-1237042 https://reactome.org/PathwayBrowser/#/R-DRE-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Danio rerio 16526 R-DRE-1237047 https://reactome.org/PathwayBrowser/#/R-DRE-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Danio rerio 16526 R-DRE-1237059 https://reactome.org/PathwayBrowser/#/R-DRE-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Danio rerio 16526 R-DRE-1237069 https://reactome.org/PathwayBrowser/#/R-DRE-1237069 RHAG transports CO2 from extracellular region to cytosol IEA Danio rerio 16526 R-DRE-1237325 https://reactome.org/PathwayBrowser/#/R-DRE-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Danio rerio 16526 R-DRE-1247645 https://reactome.org/PathwayBrowser/#/R-DRE-1247645 RHAG transports CO2 from cytosol to extracellular region IEA Danio rerio 16526 R-DRE-1247649 https://reactome.org/PathwayBrowser/#/R-DRE-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Danio rerio 16526 R-DRE-1247668 https://reactome.org/PathwayBrowser/#/R-DRE-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Danio rerio 16526 R-DRE-1475017 https://reactome.org/PathwayBrowser/#/R-DRE-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Danio rerio 16526 R-DRE-1475022 https://reactome.org/PathwayBrowser/#/R-DRE-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Danio rerio 16526 R-DRE-1475025 https://reactome.org/PathwayBrowser/#/R-DRE-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Danio rerio 16526 R-DRE-1475026 https://reactome.org/PathwayBrowser/#/R-DRE-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Danio rerio 16526 R-DRE-1475028 https://reactome.org/PathwayBrowser/#/R-DRE-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Danio rerio 16526 R-DRE-1475032 https://reactome.org/PathwayBrowser/#/R-DRE-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Danio rerio 16526 R-DRE-1475435 https://reactome.org/PathwayBrowser/#/R-DRE-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Danio rerio 16526 R-DRE-1475436 https://reactome.org/PathwayBrowser/#/R-DRE-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Danio rerio 16526 R-DRE-1650808 https://reactome.org/PathwayBrowser/#/R-DRE-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Danio rerio 16526 R-DRE-189421 https://reactome.org/PathwayBrowser/#/R-DRE-189421 CPO transforms COPRO3 to PPGEN9 IEA Danio rerio 16526 R-DRE-189425 https://reactome.org/PathwayBrowser/#/R-DRE-189425 UROD decarboxylates URO3 to COPRO3 IEA Danio rerio 16526 R-DRE-189442 https://reactome.org/PathwayBrowser/#/R-DRE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Danio rerio 16526 R-DRE-190182 https://reactome.org/PathwayBrowser/#/R-DRE-190182 UROD decarboxylates URO1 to COPRO1 IEA Danio rerio 16526 R-DRE-191414 https://reactome.org/PathwayBrowser/#/R-DRE-191414 MVD decarboxylates MVA5PP to IPPP IEA Danio rerio 16526 R-DRE-194642 https://reactome.org/PathwayBrowser/#/R-DRE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Danio rerio 16526 R-DRE-194718 https://reactome.org/PathwayBrowser/#/R-DRE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Danio rerio 16526 R-DRE-1981104 https://reactome.org/PathwayBrowser/#/R-DRE-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Danio rerio 16526 R-DRE-2046083 https://reactome.org/PathwayBrowser/#/R-DRE-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Danio rerio 16526 R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio 16526 R-DRE-2046090 https://reactome.org/PathwayBrowser/#/R-DRE-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 16526 R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio 16526 R-DRE-2046095 https://reactome.org/PathwayBrowser/#/R-DRE-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Danio rerio 16526 R-DRE-2046100 https://reactome.org/PathwayBrowser/#/R-DRE-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Danio rerio 16526 R-DRE-209859 https://reactome.org/PathwayBrowser/#/R-DRE-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Danio rerio 16526 R-DRE-209924 https://reactome.org/PathwayBrowser/#/R-DRE-209924 Dopa is decarboxylated to dopamine IEA Danio rerio 16526 R-DRE-2172678 https://reactome.org/PathwayBrowser/#/R-DRE-2172678 PHF8 demethylates histone H4K20me1 IEA Danio rerio 16526 R-DRE-350598 https://reactome.org/PathwayBrowser/#/R-DRE-350598 Arginine<=>Agmatine+CO2 IEA Danio rerio 16526 R-DRE-351222 https://reactome.org/PathwayBrowser/#/R-DRE-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Danio rerio 16526 R-DRE-372819 https://reactome.org/PathwayBrowser/#/R-DRE-372819 PCK2 phosphorylates OA to yield PEP IEA Danio rerio 16526 R-DRE-389540 https://reactome.org/PathwayBrowser/#/R-DRE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 16526 R-DRE-389550 https://reactome.org/PathwayBrowser/#/R-DRE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 16526 R-DRE-389639 https://reactome.org/PathwayBrowser/#/R-DRE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Danio rerio 16526 R-DRE-428127 https://reactome.org/PathwayBrowser/#/R-DRE-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Danio rerio 16526 R-DRE-450984 https://reactome.org/PathwayBrowser/#/R-DRE-450984 IDH2 dimer decarboxylates isocitrate IEA Danio rerio 16526 R-DRE-5423117 https://reactome.org/PathwayBrowser/#/R-DRE-5423117 PHF8 demethylates MeK21-histone H4 IEA Danio rerio 16526 R-DRE-548800 https://reactome.org/PathwayBrowser/#/R-DRE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Danio rerio 16526 R-DRE-548814 https://reactome.org/PathwayBrowser/#/R-DRE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Danio rerio 16526 R-DRE-548815 https://reactome.org/PathwayBrowser/#/R-DRE-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Danio rerio 16526 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 16526 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 16526 R-DRE-5661124 https://reactome.org/PathwayBrowser/#/R-DRE-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Danio rerio 16526 R-DRE-5661125 https://reactome.org/PathwayBrowser/#/R-DRE-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Danio rerio 16526 R-DRE-5693967 https://reactome.org/PathwayBrowser/#/R-DRE-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Danio rerio 16526 R-DRE-6808496 https://reactome.org/PathwayBrowser/#/R-DRE-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Danio rerio 16526 R-DRE-70241 https://reactome.org/PathwayBrowser/#/R-DRE-70241 PCK1 phosphorylates OA to yield PEP IEA Danio rerio 16526 R-DRE-70692 https://reactome.org/PathwayBrowser/#/R-DRE-70692 ornithine => putrescine + CO2 IEA Danio rerio 16526 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 16526 R-DRE-70893 https://reactome.org/PathwayBrowser/#/R-DRE-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Danio rerio 16526 R-DRE-71031 https://reactome.org/PathwayBrowser/#/R-DRE-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Danio rerio 16526 R-DRE-71037 https://reactome.org/PathwayBrowser/#/R-DRE-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Danio rerio 16526 R-DRE-71046 https://reactome.org/PathwayBrowser/#/R-DRE-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Danio rerio 16526 R-DRE-71163 https://reactome.org/PathwayBrowser/#/R-DRE-71163 HPD dioxygenates HPP IEA Danio rerio 16526 R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio 16526 R-DRE-71299 https://reactome.org/PathwayBrowser/#/R-DRE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Danio rerio 16526 R-DRE-71401 https://reactome.org/PathwayBrowser/#/R-DRE-71401 OGDH dimer decarboxylates 2-OG IEA Danio rerio 16526 R-DRE-73591 https://reactome.org/PathwayBrowser/#/R-DRE-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Danio rerio 16526 R-DRE-73620 https://reactome.org/PathwayBrowser/#/R-DRE-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Danio rerio 16526 R-DRE-73806 https://reactome.org/PathwayBrowser/#/R-DRE-73806 AIR + CO2 => CAIR IEA Danio rerio 16526 R-DRE-75872 https://reactome.org/PathwayBrowser/#/R-DRE-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Danio rerio 16526 R-DRE-8857692 https://reactome.org/PathwayBrowser/#/R-DRE-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Danio rerio 16526 R-DRE-888572 https://reactome.org/PathwayBrowser/#/R-DRE-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Danio rerio 16526 R-DRE-9012016 https://reactome.org/PathwayBrowser/#/R-DRE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Danio rerio 16526 R-DRE-9012036 https://reactome.org/PathwayBrowser/#/R-DRE-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Danio rerio 16526 R-DRE-9012268 https://reactome.org/PathwayBrowser/#/R-DRE-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Danio rerio 16526 R-DRE-9012349 https://reactome.org/PathwayBrowser/#/R-DRE-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Danio rerio 16526 R-DRE-9629591 https://reactome.org/PathwayBrowser/#/R-DRE-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Danio rerio 16526 R-DRE-9629869 https://reactome.org/PathwayBrowser/#/R-DRE-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Danio rerio 16526 R-DRE-9629946 https://reactome.org/PathwayBrowser/#/R-DRE-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Danio rerio 16526 R-DRE-9630993 https://reactome.org/PathwayBrowser/#/R-DRE-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Danio rerio 16526 R-DRE-977317 https://reactome.org/PathwayBrowser/#/R-DRE-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Danio rerio 16526 R-DRE-9861660 https://reactome.org/PathwayBrowser/#/R-DRE-9861660 ME1 tetramer decarboxylates OA to PYR IEA Danio rerio 16526 R-GGA-1234164 https://reactome.org/PathwayBrowser/#/R-GGA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Gallus gallus 16526 R-GGA-1234165 https://reactome.org/PathwayBrowser/#/R-GGA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 16526 R-GGA-1234173 https://reactome.org/PathwayBrowser/#/R-GGA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 16526 R-GGA-1234177 https://reactome.org/PathwayBrowser/#/R-GGA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 16526 R-GGA-1234181 https://reactome.org/PathwayBrowser/#/R-GGA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 16526 R-GGA-1237042 https://reactome.org/PathwayBrowser/#/R-GGA-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Gallus gallus 16526 R-GGA-1237045 https://reactome.org/PathwayBrowser/#/R-GGA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Gallus gallus 16526 R-GGA-1237047 https://reactome.org/PathwayBrowser/#/R-GGA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Gallus gallus 16526 R-GGA-1237059 https://reactome.org/PathwayBrowser/#/R-GGA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Gallus gallus 16526 R-GGA-1237069 https://reactome.org/PathwayBrowser/#/R-GGA-1237069 RHAG transports CO2 from extracellular region to cytosol IEA Gallus gallus 16526 R-GGA-1237081 https://reactome.org/PathwayBrowser/#/R-GGA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Gallus gallus 16526 R-GGA-1237325 https://reactome.org/PathwayBrowser/#/R-GGA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Gallus gallus 16526 R-GGA-1247645 https://reactome.org/PathwayBrowser/#/R-GGA-1247645 RHAG transports CO2 from cytosol to extracellular region IEA Gallus gallus 16526 R-GGA-1247649 https://reactome.org/PathwayBrowser/#/R-GGA-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Gallus gallus 16526 R-GGA-1247668 https://reactome.org/PathwayBrowser/#/R-GGA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Gallus gallus 16526 R-GGA-1475017 https://reactome.org/PathwayBrowser/#/R-GGA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Gallus gallus 16526 R-GGA-1475022 https://reactome.org/PathwayBrowser/#/R-GGA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Gallus gallus 16526 R-GGA-1475025 https://reactome.org/PathwayBrowser/#/R-GGA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Gallus gallus 16526 R-GGA-1475026 https://reactome.org/PathwayBrowser/#/R-GGA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Gallus gallus 16526 R-GGA-1475028 https://reactome.org/PathwayBrowser/#/R-GGA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Gallus gallus 16526 R-GGA-1475032 https://reactome.org/PathwayBrowser/#/R-GGA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Gallus gallus 16526 R-GGA-1475435 https://reactome.org/PathwayBrowser/#/R-GGA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Gallus gallus 16526 R-GGA-1475436 https://reactome.org/PathwayBrowser/#/R-GGA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Gallus gallus 16526 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus 16526 R-GGA-189421 https://reactome.org/PathwayBrowser/#/R-GGA-189421 CPO transforms COPRO3 to PPGEN9 IEA Gallus gallus 16526 R-GGA-189425 https://reactome.org/PathwayBrowser/#/R-GGA-189425 UROD decarboxylates URO3 to COPRO3 IEA Gallus gallus 16526 R-GGA-189442 https://reactome.org/PathwayBrowser/#/R-GGA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Gallus gallus 16526 R-GGA-190182 https://reactome.org/PathwayBrowser/#/R-GGA-190182 UROD decarboxylates URO1 to COPRO1 IEA Gallus gallus 16526 R-GGA-191414 https://reactome.org/PathwayBrowser/#/R-GGA-191414 MVD decarboxylates MVA5PP to IPPP IEA Gallus gallus 16526 R-GGA-194642 https://reactome.org/PathwayBrowser/#/R-GGA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Gallus gallus 16526 R-GGA-194718 https://reactome.org/PathwayBrowser/#/R-GGA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Gallus gallus 16526 R-GGA-196840 https://reactome.org/PathwayBrowser/#/R-GGA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Gallus gallus 16526 R-GGA-197268 https://reactome.org/PathwayBrowser/#/R-GGA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Gallus gallus 16526 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus 16526 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus 16526 R-GGA-2046083 https://reactome.org/PathwayBrowser/#/R-GGA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Gallus gallus 16526 R-GGA-2046088 https://reactome.org/PathwayBrowser/#/R-GGA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Gallus gallus 16526 R-GGA-2046090 https://reactome.org/PathwayBrowser/#/R-GGA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 16526 R-GGA-2046094 https://reactome.org/PathwayBrowser/#/R-GGA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Gallus gallus 16526 R-GGA-2046095 https://reactome.org/PathwayBrowser/#/R-GGA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Gallus gallus 16526 R-GGA-2046100 https://reactome.org/PathwayBrowser/#/R-GGA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Gallus gallus 16526 R-GGA-209859 https://reactome.org/PathwayBrowser/#/R-GGA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Gallus gallus 16526 R-GGA-209924 https://reactome.org/PathwayBrowser/#/R-GGA-209924 Dopa is decarboxylated to dopamine IEA Gallus gallus 16526 R-GGA-2172678 https://reactome.org/PathwayBrowser/#/R-GGA-2172678 PHF8 demethylates histone H4K20me1 IEA Gallus gallus 16526 R-GGA-350598 https://reactome.org/PathwayBrowser/#/R-GGA-350598 Arginine<=>Agmatine+CO2 IEA Gallus gallus 16526 R-GGA-351222 https://reactome.org/PathwayBrowser/#/R-GGA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Gallus gallus 16526 R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 16526 R-GGA-353356 https://reactome.org/PathwayBrowser/#/R-GGA-353356 Reversal of Alkylation Damage By DNA Dioxygenases TAS Gallus gallus 16526 R-GGA-372724 https://reactome.org/PathwayBrowser/#/R-GGA-372724 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] TAS Gallus gallus 16526 R-GGA-372741 https://reactome.org/PathwayBrowser/#/R-GGA-372741 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] TAS Gallus gallus 16526 R-GGA-372819 https://reactome.org/PathwayBrowser/#/R-GGA-372819 PCK2 phosphorylates OA to yield PEP IEA Gallus gallus 16526 R-GGA-373024 https://reactome.org/PathwayBrowser/#/R-GGA-373024 isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ IEA Gallus gallus 16526 R-GGA-373042 https://reactome.org/PathwayBrowser/#/R-GGA-373042 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ IEA Gallus gallus 16526 R-GGA-373177 https://reactome.org/PathwayBrowser/#/R-GGA-373177 pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ TAS Gallus gallus 16526 R-GGA-389540 https://reactome.org/PathwayBrowser/#/R-GGA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 16526 R-GGA-389550 https://reactome.org/PathwayBrowser/#/R-GGA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 16526 R-GGA-389639 https://reactome.org/PathwayBrowser/#/R-GGA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Gallus gallus 16526 R-GGA-419214 https://reactome.org/PathwayBrowser/#/R-GGA-419214 5'-phosphoribosyl-5-aminoimidazole (AIR) + CO2 <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) TAS Gallus gallus 16526 R-GGA-419461 https://reactome.org/PathwayBrowser/#/R-GGA-419461 orotidine 5'-monophosphate => uridine 5'-monophosphate + CO2 IEA Gallus gallus 16526 R-GGA-421459 https://reactome.org/PathwayBrowser/#/R-GGA-421459 uroporphyrinogen I => coproporphyrinogen I + 4 CO2 IEA Gallus gallus 16526 R-GGA-421478 https://reactome.org/PathwayBrowser/#/R-GGA-421478 coproporphyrinogen III + 2 O2 => protoporphyrinogen IX + 2 H2O2 + 2 CO2 IEA Gallus gallus 16526 R-GGA-421493 https://reactome.org/PathwayBrowser/#/R-GGA-421493 succinyl-CoA + glycine => delta-aminolevulinate + CoA SH + CO2 TAS Gallus gallus 16526 R-GGA-421515 https://reactome.org/PathwayBrowser/#/R-GGA-421515 uroporphyrinogen III => coproporphyrinogen III + 4 CO2 IEA Gallus gallus 16526 R-GGA-428127 https://reactome.org/PathwayBrowser/#/R-GGA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Gallus gallus 16526 R-GGA-433550 https://reactome.org/PathwayBrowser/#/R-GGA-433550 palmitoyl-CoA + serine => 3-dehydrosphinganine + CoASH + CO2 IEA Gallus gallus 16526 R-GGA-450984 https://reactome.org/PathwayBrowser/#/R-GGA-450984 IDH2 dimer decarboxylates isocitrate IEA Gallus gallus 16526 R-GGA-548800 https://reactome.org/PathwayBrowser/#/R-GGA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Gallus gallus 16526 R-GGA-548814 https://reactome.org/PathwayBrowser/#/R-GGA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Gallus gallus 16526 R-GGA-548815 https://reactome.org/PathwayBrowser/#/R-GGA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Gallus gallus 16526 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 16526 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 16526 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 16526 R-GGA-5661124 https://reactome.org/PathwayBrowser/#/R-GGA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Gallus gallus 16526 R-GGA-5661125 https://reactome.org/PathwayBrowser/#/R-GGA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Gallus gallus 16526 R-GGA-5693967 https://reactome.org/PathwayBrowser/#/R-GGA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Gallus gallus 16526 R-GGA-6787757 https://reactome.org/PathwayBrowser/#/R-GGA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Gallus gallus 16526 R-GGA-6808487 https://reactome.org/PathwayBrowser/#/R-GGA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Gallus gallus 16526 R-GGA-6814165 https://reactome.org/PathwayBrowser/#/R-GGA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Gallus gallus 16526 R-GGA-70241 https://reactome.org/PathwayBrowser/#/R-GGA-70241 PCK1 phosphorylates OA to yield PEP IEA Gallus gallus 16526 R-GGA-70692 https://reactome.org/PathwayBrowser/#/R-GGA-70692 ornithine => putrescine + CO2 IEA Gallus gallus 16526 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 16526 R-GGA-70893 https://reactome.org/PathwayBrowser/#/R-GGA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Gallus gallus 16526 R-GGA-71031 https://reactome.org/PathwayBrowser/#/R-GGA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Gallus gallus 16526 R-GGA-71037 https://reactome.org/PathwayBrowser/#/R-GGA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Gallus gallus 16526 R-GGA-71046 https://reactome.org/PathwayBrowser/#/R-GGA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Gallus gallus 16526 R-GGA-71163 https://reactome.org/PathwayBrowser/#/R-GGA-71163 HPD dioxygenates HPP IEA Gallus gallus 16526 R-GGA-71241 https://reactome.org/PathwayBrowser/#/R-GGA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Gallus gallus 16526 R-GGA-71261 https://reactome.org/PathwayBrowser/#/R-GGA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Gallus gallus 16526 R-GGA-71299 https://reactome.org/PathwayBrowser/#/R-GGA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Gallus gallus 16526 R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus 16526 R-GGA-73564 https://reactome.org/PathwayBrowser/#/R-GGA-73564 UMPS dimer decarboxylates OMP to UMP IEA Gallus gallus 16526 R-GGA-73591 https://reactome.org/PathwayBrowser/#/R-GGA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Gallus gallus 16526 R-GGA-73620 https://reactome.org/PathwayBrowser/#/R-GGA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Gallus gallus 16526 R-GGA-73806 https://reactome.org/PathwayBrowser/#/R-GGA-73806 AIR + CO2 => CAIR IEA Gallus gallus 16526 R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Gallus gallus 16526 R-GGA-8857692 https://reactome.org/PathwayBrowser/#/R-GGA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Gallus gallus 16526 R-GGA-888572 https://reactome.org/PathwayBrowser/#/R-GGA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Gallus gallus 16526 R-GGA-888577 https://reactome.org/PathwayBrowser/#/R-GGA-888577 Synthesis of GABA by GAD2 IEA Gallus gallus 16526 R-GGA-9012016 https://reactome.org/PathwayBrowser/#/R-GGA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Gallus gallus 16526 R-GGA-9012036 https://reactome.org/PathwayBrowser/#/R-GGA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Gallus gallus 16526 R-GGA-9012349 https://reactome.org/PathwayBrowser/#/R-GGA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Gallus gallus 16526 R-GGA-9629578 https://reactome.org/PathwayBrowser/#/R-GGA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Gallus gallus 16526 R-GGA-9629591 https://reactome.org/PathwayBrowser/#/R-GGA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Gallus gallus 16526 R-GGA-9629869 https://reactome.org/PathwayBrowser/#/R-GGA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Gallus gallus 16526 R-GGA-9629946 https://reactome.org/PathwayBrowser/#/R-GGA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Gallus gallus 16526 R-GGA-9630022 https://reactome.org/PathwayBrowser/#/R-GGA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Gallus gallus 16526 R-GGA-9630769 https://reactome.org/PathwayBrowser/#/R-GGA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Gallus gallus 16526 R-GGA-9630967 https://reactome.org/PathwayBrowser/#/R-GGA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Gallus gallus 16526 R-GGA-9630993 https://reactome.org/PathwayBrowser/#/R-GGA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Gallus gallus 16526 R-GGA-977301 https://reactome.org/PathwayBrowser/#/R-GGA-977301 Histidine is decarboxylated to histamine IEA Gallus gallus 16526 R-GGA-977317 https://reactome.org/PathwayBrowser/#/R-GGA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Gallus gallus 16526 R-GGA-9861660 https://reactome.org/PathwayBrowser/#/R-GGA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Gallus gallus 16526 R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus 16526 R-HSA-112118 https://reactome.org/PathwayBrowser/#/R-HSA-112118 Oxidative demethylation of 1-meA damaged DNA by ALKBH2 TAS Homo sapiens 16526 R-HSA-112120 https://reactome.org/PathwayBrowser/#/R-HSA-112120 Oxidative demethylation of 3-meC damaged DNA by ALKBH2 TAS Homo sapiens 16526 R-HSA-112121 https://reactome.org/PathwayBrowser/#/R-HSA-112121 Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 TAS Homo sapiens 16526 R-HSA-112123 https://reactome.org/PathwayBrowser/#/R-HSA-112123 Oxidative demethylation of 1-meA damaged DNA By ALKBH3 TAS Homo sapiens 16526 R-HSA-112124 https://reactome.org/PathwayBrowser/#/R-HSA-112124 Oxidative demethylation of 3-meC damaged DNA By ALKBH3 TAS Homo sapiens 16526 R-HSA-112125 https://reactome.org/PathwayBrowser/#/R-HSA-112125 Oxidative dealkylation of 1-EtA damaged DNA by ABH3 TAS Homo sapiens 16526 R-HSA-1234164 https://reactome.org/PathwayBrowser/#/R-HSA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) TAS Homo sapiens 16526 R-HSA-1234165 https://reactome.org/PathwayBrowser/#/R-HSA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 16526 R-HSA-1234166 https://reactome.org/PathwayBrowser/#/R-HSA-1234166 Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 16526 R-HSA-1234173 https://reactome.org/PathwayBrowser/#/R-HSA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 16526 R-HSA-1234177 https://reactome.org/PathwayBrowser/#/R-HSA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 16526 R-HSA-1234179 https://reactome.org/PathwayBrowser/#/R-HSA-1234179 Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 16526 R-HSA-1234181 https://reactome.org/PathwayBrowser/#/R-HSA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 16526 R-HSA-1237042 https://reactome.org/PathwayBrowser/#/R-HSA-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol TAS Homo sapiens 16526 R-HSA-1237045 https://reactome.org/PathwayBrowser/#/R-HSA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton TAS Homo sapiens 16526 R-HSA-1237047 https://reactome.org/PathwayBrowser/#/R-HSA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- TAS Homo sapiens 16526 R-HSA-1237059 https://reactome.org/PathwayBrowser/#/R-HSA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 TAS Homo sapiens 16526 R-HSA-1237069 https://reactome.org/PathwayBrowser/#/R-HSA-1237069 RHAG transports CO2 from extracellular region to cytosol TAS Homo sapiens 16526 R-HSA-1237081 https://reactome.org/PathwayBrowser/#/R-HSA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide TAS Homo sapiens 16526 R-HSA-1237325 https://reactome.org/PathwayBrowser/#/R-HSA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen TAS Homo sapiens 16526 R-HSA-1247645 https://reactome.org/PathwayBrowser/#/R-HSA-1247645 RHAG transports CO2 from cytosol to extracellular region TAS Homo sapiens 16526 R-HSA-1247649 https://reactome.org/PathwayBrowser/#/R-HSA-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region TAS Homo sapiens 16526 R-HSA-1247668 https://reactome.org/PathwayBrowser/#/R-HSA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 TAS Homo sapiens 16526 R-HSA-1475017 https://reactome.org/PathwayBrowser/#/R-HSA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) TAS Homo sapiens 16526 R-HSA-1475022 https://reactome.org/PathwayBrowser/#/R-HSA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) TAS Homo sapiens 16526 R-HSA-1475025 https://reactome.org/PathwayBrowser/#/R-HSA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) TAS Homo sapiens 16526 R-HSA-1475026 https://reactome.org/PathwayBrowser/#/R-HSA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) TAS Homo sapiens 16526 R-HSA-1475028 https://reactome.org/PathwayBrowser/#/R-HSA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) TAS Homo sapiens 16526 R-HSA-1475032 https://reactome.org/PathwayBrowser/#/R-HSA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) TAS Homo sapiens 16526 R-HSA-1475435 https://reactome.org/PathwayBrowser/#/R-HSA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- TAS Homo sapiens 16526 R-HSA-1475436 https://reactome.org/PathwayBrowser/#/R-HSA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 TAS Homo sapiens 16526 R-HSA-1483212 https://reactome.org/PathwayBrowser/#/R-HSA-1483212 PS is decarboxylated to PE by PISD IEA Homo sapiens 16526 R-HSA-159752 https://reactome.org/PathwayBrowser/#/R-HSA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) TAS Homo sapiens 16526 R-HSA-159761 https://reactome.org/PathwayBrowser/#/R-HSA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) TAS Homo sapiens 16526 R-HSA-159795 https://reactome.org/PathwayBrowser/#/R-HSA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) TAS Homo sapiens 16526 R-HSA-159803 https://reactome.org/PathwayBrowser/#/R-HSA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) TAS Homo sapiens 16526 R-HSA-159819 https://reactome.org/PathwayBrowser/#/R-HSA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) TAS Homo sapiens 16526 R-HSA-159826 https://reactome.org/PathwayBrowser/#/R-HSA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) TAS Homo sapiens 16526 R-HSA-163810 https://reactome.org/PathwayBrowser/#/R-HSA-163810 GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6) IEA Homo sapiens 16526 R-HSA-163820 https://reactome.org/PathwayBrowser/#/R-HSA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) TAS Homo sapiens 16526 R-HSA-1650808 https://reactome.org/PathwayBrowser/#/R-HSA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines TAS Homo sapiens 16526 R-HSA-1655443 https://reactome.org/PathwayBrowser/#/R-HSA-1655443 PXKLP-K305-CSAD decarboxylates 3-sulfinoalanine to hypotaurine IEA Homo sapiens 16526 R-HSA-189421 https://reactome.org/PathwayBrowser/#/R-HSA-189421 CPO transforms COPRO3 to PPGEN9 TAS Homo sapiens 16526 R-HSA-189425 https://reactome.org/PathwayBrowser/#/R-HSA-189425 UROD decarboxylates URO3 to COPRO3 TAS Homo sapiens 16526 R-HSA-189442 https://reactome.org/PathwayBrowser/#/R-HSA-189442 ALAS condenses SUCC-CoA and Gly to form dALA TAS Homo sapiens 16526 R-HSA-190182 https://reactome.org/PathwayBrowser/#/R-HSA-190182 UROD decarboxylates URO1 to COPRO1 TAS Homo sapiens 16526 R-HSA-191414 https://reactome.org/PathwayBrowser/#/R-HSA-191414 MVD decarboxylates MVA5PP to IPPP TAS Homo sapiens 16526 R-HSA-194642 https://reactome.org/PathwayBrowser/#/R-HSA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one TAS Homo sapiens 16526 R-HSA-194718 https://reactome.org/PathwayBrowser/#/R-HSA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) TAS Homo sapiens 16526 R-HSA-196840 https://reactome.org/PathwayBrowser/#/R-HSA-196840 3xPPCDC:3FMN decarboxylates PPC TAS Homo sapiens 16526 R-HSA-197268 https://reactome.org/PathwayBrowser/#/R-HSA-197268 QPRT transfers PRIB to QUIN to form NAMN TAS Homo sapiens 16526 R-HSA-1980233 https://reactome.org/PathwayBrowser/#/R-HSA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen TAS Homo sapiens 16526 R-HSA-1981104 https://reactome.org/PathwayBrowser/#/R-HSA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines TAS Homo sapiens 16526 R-HSA-2046083 https://reactome.org/PathwayBrowser/#/R-HSA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA TAS Homo sapiens 16526 R-HSA-2046088 https://reactome.org/PathwayBrowser/#/R-HSA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA TAS Homo sapiens 16526 R-HSA-2046090 https://reactome.org/PathwayBrowser/#/R-HSA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 16526 R-HSA-2046094 https://reactome.org/PathwayBrowser/#/R-HSA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA TAS Homo sapiens 16526 R-HSA-2046095 https://reactome.org/PathwayBrowser/#/R-HSA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA TAS Homo sapiens 16526 R-HSA-2046100 https://reactome.org/PathwayBrowser/#/R-HSA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA TAS Homo sapiens 16526 R-HSA-209859 https://reactome.org/PathwayBrowser/#/R-HSA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin TAS Homo sapiens 16526 R-HSA-209924 https://reactome.org/PathwayBrowser/#/R-HSA-209924 Dopa is decarboxylated to dopamine TAS Homo sapiens 16526 R-HSA-2162195 https://reactome.org/PathwayBrowser/#/R-HSA-2162195 Unknown enzyme decarboxylates MHDB IEA Homo sapiens 16526 R-HSA-2172678 https://reactome.org/PathwayBrowser/#/R-HSA-2172678 PHF8 demethylates histone H4K20me1 TAS Homo sapiens 16526 R-HSA-350598 https://reactome.org/PathwayBrowser/#/R-HSA-350598 Arginine<=>Agmatine+CO2 TAS Homo sapiens 16526 R-HSA-351222 https://reactome.org/PathwayBrowser/#/R-HSA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 TAS Homo sapiens 16526 R-HSA-372819 https://reactome.org/PathwayBrowser/#/R-HSA-372819 PCK2 phosphorylates OA to yield PEP TAS Homo sapiens 16526 R-HSA-389540 https://reactome.org/PathwayBrowser/#/R-HSA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 16526 R-HSA-389550 https://reactome.org/PathwayBrowser/#/R-HSA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 16526 R-HSA-389639 https://reactome.org/PathwayBrowser/#/R-HSA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 TAS Homo sapiens 16526 R-HSA-428127 https://reactome.org/PathwayBrowser/#/R-HSA-428127 SPTLC complexes transfer acyl-CoA onto serine TAS Homo sapiens 16526 R-HSA-450984 https://reactome.org/PathwayBrowser/#/R-HSA-450984 IDH2 dimer decarboxylates isocitrate TAS Homo sapiens 16526 R-HSA-4722133 https://reactome.org/PathwayBrowser/#/R-HSA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 TAS Homo sapiens 16526 R-HSA-4724279 https://reactome.org/PathwayBrowser/#/R-HSA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 TAS Homo sapiens 16526 R-HSA-4724284 https://reactome.org/PathwayBrowser/#/R-HSA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 TAS Homo sapiens 16526 R-HSA-4754176 https://reactome.org/PathwayBrowser/#/R-HSA-4754176 JMJD6 demethylates MeR3-histone H3 TAS Homo sapiens 16526 R-HSA-4754181 https://reactome.org/PathwayBrowser/#/R-HSA-4754181 KDM5A-D demethylate Me2K5-histone H3 TAS Homo sapiens 16526 R-HSA-4754187 https://reactome.org/PathwayBrowser/#/R-HSA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 TAS Homo sapiens 16526 R-HSA-5220952 https://reactome.org/PathwayBrowser/#/R-HSA-5220952 TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine IEA Homo sapiens 16526 R-HSA-5220990 https://reactome.org/PathwayBrowser/#/R-HSA-5220990 TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine IEA Homo sapiens 16526 R-HSA-5221014 https://reactome.org/PathwayBrowser/#/R-HSA-5221014 TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine IEA Homo sapiens 16526 R-HSA-5423117 https://reactome.org/PathwayBrowser/#/R-HSA-5423117 PHF8 demethylates MeK21-histone H4 TAS Homo sapiens 16526 R-HSA-548800 https://reactome.org/PathwayBrowser/#/R-HSA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA TAS Homo sapiens 16526 R-HSA-548814 https://reactome.org/PathwayBrowser/#/R-HSA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA TAS Homo sapiens 16526 R-HSA-548815 https://reactome.org/PathwayBrowser/#/R-HSA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA TAS Homo sapiens 16526 R-HSA-548830 https://reactome.org/PathwayBrowser/#/R-HSA-548830 ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA IEA Homo sapiens 16526 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 16526 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 16526 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 16526 R-HSA-5661114 https://reactome.org/PathwayBrowser/#/R-HSA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 TAS Homo sapiens 16526 R-HSA-5661115 https://reactome.org/PathwayBrowser/#/R-HSA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 TAS Homo sapiens 16526 R-HSA-5661116 https://reactome.org/PathwayBrowser/#/R-HSA-5661116 KDM5A-D demethylate Me3K5-histone H3 TAS Homo sapiens 16526 R-HSA-5661120 https://reactome.org/PathwayBrowser/#/R-HSA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 TAS Homo sapiens 16526 R-HSA-5661121 https://reactome.org/PathwayBrowser/#/R-HSA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 TAS Homo sapiens 16526 R-HSA-5661122 https://reactome.org/PathwayBrowser/#/R-HSA-5661122 JMJD6 demethylates Me2R3-histone H3 TAS Homo sapiens 16526 R-HSA-5661124 https://reactome.org/PathwayBrowser/#/R-HSA-5661124 JMJD6 demethylates MeR4-HIST1H4 TAS Homo sapiens 16526 R-HSA-5661125 https://reactome.org/PathwayBrowser/#/R-HSA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 TAS Homo sapiens 16526 R-HSA-5662473 https://reactome.org/PathwayBrowser/#/R-HSA-5662473 KGPDC decarboxylates 3-dehydro-L-gulonate to L-xylulose TAS Homo sapiens 16526 R-HSA-5662706 https://reactome.org/PathwayBrowser/#/R-HSA-5662706 Dopachrome transforms to DHI TAS Homo sapiens 16526 R-HSA-5693967 https://reactome.org/PathwayBrowser/#/R-HSA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly TAS Homo sapiens 16526 R-HSA-6782890 https://reactome.org/PathwayBrowser/#/R-HSA-6782890 LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 16526 R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 16526 R-HSA-6783455 https://reactome.org/PathwayBrowser/#/R-HSA-6783455 TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 16526 R-HSA-6783473 https://reactome.org/PathwayBrowser/#/R-HSA-6783473 LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 16526 R-HSA-6787757 https://reactome.org/PathwayBrowser/#/R-HSA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs TAS Homo sapiens 16526 R-HSA-6807214 https://reactome.org/PathwayBrowser/#/R-HSA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) TAS Homo sapiens 16526 R-HSA-6808487 https://reactome.org/PathwayBrowser/#/R-HSA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 16526 R-HSA-6808496 https://reactome.org/PathwayBrowser/#/R-HSA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 16526 R-HSA-6814165 https://reactome.org/PathwayBrowser/#/R-HSA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU TAS Homo sapiens 16526 R-HSA-70241 https://reactome.org/PathwayBrowser/#/R-HSA-70241 PCK1 phosphorylates OA to yield PEP TAS Homo sapiens 16526 R-HSA-70692 https://reactome.org/PathwayBrowser/#/R-HSA-70692 ornithine => putrescine + CO2 TAS Homo sapiens 16526 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 16526 R-HSA-70893 https://reactome.org/PathwayBrowser/#/R-HSA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ TAS Homo sapiens 16526 R-HSA-70967 https://reactome.org/PathwayBrowser/#/R-HSA-70967 IDH3 complex decarboxylates isocitrate TAS Homo sapiens 16526 R-HSA-71031 https://reactome.org/PathwayBrowser/#/R-HSA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate TAS Homo sapiens 16526 R-HSA-71037 https://reactome.org/PathwayBrowser/#/R-HSA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ TAS Homo sapiens 16526 R-HSA-71046 https://reactome.org/PathwayBrowser/#/R-HSA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 TAS Homo sapiens 16526 R-HSA-71163 https://reactome.org/PathwayBrowser/#/R-HSA-71163 HPD dioxygenates HPP TAS Homo sapiens 16526 R-HSA-71223 https://reactome.org/PathwayBrowser/#/R-HSA-71223 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 IEA Homo sapiens 16526 R-HSA-71241 https://reactome.org/PathwayBrowser/#/R-HSA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA TAS Homo sapiens 16526 R-HSA-71261 https://reactome.org/PathwayBrowser/#/R-HSA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA TAS Homo sapiens 16526 R-HSA-71299 https://reactome.org/PathwayBrowser/#/R-HSA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ TAS Homo sapiens 16526 R-HSA-71401 https://reactome.org/PathwayBrowser/#/R-HSA-71401 OGDH dimer decarboxylates 2-OG TAS Homo sapiens 16526 R-HSA-73564 https://reactome.org/PathwayBrowser/#/R-HSA-73564 UMPS dimer decarboxylates OMP to UMP TAS Homo sapiens 16526 R-HSA-73591 https://reactome.org/PathwayBrowser/#/R-HSA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 TAS Homo sapiens 16526 R-HSA-73620 https://reactome.org/PathwayBrowser/#/R-HSA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 TAS Homo sapiens 16526 R-HSA-73806 https://reactome.org/PathwayBrowser/#/R-HSA-73806 AIR + CO2 => CAIR TAS Homo sapiens 16526 R-HSA-75872 https://reactome.org/PathwayBrowser/#/R-HSA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O TAS Homo sapiens 16526 R-HSA-8857692 https://reactome.org/PathwayBrowser/#/R-HSA-8857692 RNA demethylases demethylate N6-methyladenosine RNA TAS Homo sapiens 16526 R-HSA-888572 https://reactome.org/PathwayBrowser/#/R-HSA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA TAS Homo sapiens 16526 R-HSA-888577 https://reactome.org/PathwayBrowser/#/R-HSA-888577 Synthesis of GABA by GAD2 TAS Homo sapiens 16526 R-HSA-8942075 https://reactome.org/PathwayBrowser/#/R-HSA-8942075 Peroxynitrite and carbon dioxide react to nitrosoperoxycarbonate TAS Homo sapiens 16526 R-HSA-9012016 https://reactome.org/PathwayBrowser/#/R-HSA-9012016 FAHD1 dimer hydrolyses OA to PYR TAS Homo sapiens 16526 R-HSA-9012036 https://reactome.org/PathwayBrowser/#/R-HSA-9012036 ME1 tetramer decarboxylates MAL to PYR TAS Homo sapiens 16526 R-HSA-9012268 https://reactome.org/PathwayBrowser/#/R-HSA-9012268 ME2 tetramer decarboxylates MAL to PYR TAS Homo sapiens 16526 R-HSA-9012349 https://reactome.org/PathwayBrowser/#/R-HSA-9012349 ME3 tetramer decarboxylates MAL to PYR TAS Homo sapiens 16526 R-HSA-9629578 https://reactome.org/PathwayBrowser/#/R-HSA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 TAS Homo sapiens 16526 R-HSA-9629591 https://reactome.org/PathwayBrowser/#/R-HSA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 TAS Homo sapiens 16526 R-HSA-9629869 https://reactome.org/PathwayBrowser/#/R-HSA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 TAS Homo sapiens 16526 R-HSA-9629888 https://reactome.org/PathwayBrowser/#/R-HSA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 TAS Homo sapiens 16526 R-HSA-9629946 https://reactome.org/PathwayBrowser/#/R-HSA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 TAS Homo sapiens 16526 R-HSA-9630022 https://reactome.org/PathwayBrowser/#/R-HSA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 TAS Homo sapiens 16526 R-HSA-9630769 https://reactome.org/PathwayBrowser/#/R-HSA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 TAS Homo sapiens 16526 R-HSA-9630967 https://reactome.org/PathwayBrowser/#/R-HSA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A TAS Homo sapiens 16526 R-HSA-9630993 https://reactome.org/PathwayBrowser/#/R-HSA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 TAS Homo sapiens 16526 R-HSA-9631355 https://reactome.org/PathwayBrowser/#/R-HSA-9631355 ASPH:Fe2+ hydroxylates an aspartate residue of F9 IEA Homo sapiens 16526 R-HSA-9673231 https://reactome.org/PathwayBrowser/#/R-HSA-9673231 GGCX does not gamma-carboxylate 3D-F9(29-461) (pro-factor IX) TAS Homo sapiens 16526 R-HSA-977301 https://reactome.org/PathwayBrowser/#/R-HSA-977301 Histidine is decarboxylated to histamine TAS Homo sapiens 16526 R-HSA-977317 https://reactome.org/PathwayBrowser/#/R-HSA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome TAS Homo sapiens 16526 R-HSA-9817458 https://reactome.org/PathwayBrowser/#/R-HSA-9817458 TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 IEA Homo sapiens 16526 R-HSA-9822461 https://reactome.org/PathwayBrowser/#/R-HSA-9822461 KDM5B demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 16526 R-HSA-9822467 https://reactome.org/PathwayBrowser/#/R-HSA-9822467 KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 16526 R-HSA-9822914 https://reactome.org/PathwayBrowser/#/R-HSA-9822914 KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 16526 R-HSA-9822985 https://reactome.org/PathwayBrowser/#/R-HSA-9822985 KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 16526 R-HSA-9861595 https://reactome.org/PathwayBrowser/#/R-HSA-9861595 Cytosolic H2O2 decarboxylates PYR to acetate TAS Homo sapiens 16526 R-HSA-9861660 https://reactome.org/PathwayBrowser/#/R-HSA-9861660 ME1 tetramer decarboxylates OA to PYR TAS Homo sapiens 16526 R-HSA-9861734 https://reactome.org/PathwayBrowser/#/R-HSA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT TAS Homo sapiens 16526 R-HSA-9861745 https://reactome.org/PathwayBrowser/#/R-HSA-9861745 Mitochondrial H2O2 decarboxylates PYR to acetate TAS Homo sapiens 16526 R-MMU-1234164 https://reactome.org/PathwayBrowser/#/R-MMU-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Mus musculus 16526 R-MMU-1234165 https://reactome.org/PathwayBrowser/#/R-MMU-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Mus musculus 16526 R-MMU-1234173 https://reactome.org/PathwayBrowser/#/R-MMU-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Mus musculus 16526 R-MMU-1234177 https://reactome.org/PathwayBrowser/#/R-MMU-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Mus musculus 16526 R-MMU-1234181 https://reactome.org/PathwayBrowser/#/R-MMU-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Mus musculus 16526 R-MMU-1237042 https://reactome.org/PathwayBrowser/#/R-MMU-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Mus musculus 16526 R-MMU-1237045 https://reactome.org/PathwayBrowser/#/R-MMU-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Mus musculus 16526 R-MMU-1237047 https://reactome.org/PathwayBrowser/#/R-MMU-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Mus musculus 16526 R-MMU-1237059 https://reactome.org/PathwayBrowser/#/R-MMU-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Mus musculus 16526 R-MMU-1237069 https://reactome.org/PathwayBrowser/#/R-MMU-1237069 RHAG transports CO2 from extracellular region to cytosol IEA Mus musculus 16526 R-MMU-1237081 https://reactome.org/PathwayBrowser/#/R-MMU-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Mus musculus 16526 R-MMU-1237325 https://reactome.org/PathwayBrowser/#/R-MMU-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Mus musculus 16526 R-MMU-1247645 https://reactome.org/PathwayBrowser/#/R-MMU-1247645 RHAG transports CO2 from cytosol to extracellular region IEA Mus musculus 16526 R-MMU-1247649 https://reactome.org/PathwayBrowser/#/R-MMU-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Mus musculus 16526 R-MMU-1247668 https://reactome.org/PathwayBrowser/#/R-MMU-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Mus musculus 16526 R-MMU-1475017 https://reactome.org/PathwayBrowser/#/R-MMU-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Mus musculus 16526 R-MMU-1475022 https://reactome.org/PathwayBrowser/#/R-MMU-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Mus musculus 16526 R-MMU-1475025 https://reactome.org/PathwayBrowser/#/R-MMU-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Mus musculus 16526 R-MMU-1475026 https://reactome.org/PathwayBrowser/#/R-MMU-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Mus musculus 16526 R-MMU-1475028 https://reactome.org/PathwayBrowser/#/R-MMU-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Mus musculus 16526 R-MMU-1475032 https://reactome.org/PathwayBrowser/#/R-MMU-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Mus musculus 16526 R-MMU-1475435 https://reactome.org/PathwayBrowser/#/R-MMU-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Mus musculus 16526 R-MMU-1475436 https://reactome.org/PathwayBrowser/#/R-MMU-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Mus musculus 16526 R-MMU-159752 https://reactome.org/PathwayBrowser/#/R-MMU-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Mus musculus 16526 R-MMU-159761 https://reactome.org/PathwayBrowser/#/R-MMU-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Mus musculus 16526 R-MMU-159795 https://reactome.org/PathwayBrowser/#/R-MMU-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Mus musculus 16526 R-MMU-159803 https://reactome.org/PathwayBrowser/#/R-MMU-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Mus musculus 16526 R-MMU-159819 https://reactome.org/PathwayBrowser/#/R-MMU-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Mus musculus 16526 R-MMU-159826 https://reactome.org/PathwayBrowser/#/R-MMU-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Mus musculus 16526 R-MMU-163820 https://reactome.org/PathwayBrowser/#/R-MMU-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Mus musculus 16526 R-MMU-1650808 https://reactome.org/PathwayBrowser/#/R-MMU-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Mus musculus 16526 R-MMU-189421 https://reactome.org/PathwayBrowser/#/R-MMU-189421 CPO transforms COPRO3 to PPGEN9 IEA Mus musculus 16526 R-MMU-189425 https://reactome.org/PathwayBrowser/#/R-MMU-189425 UROD decarboxylates URO3 to COPRO3 IEA Mus musculus 16526 R-MMU-189442 https://reactome.org/PathwayBrowser/#/R-MMU-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Mus musculus 16526 R-MMU-190182 https://reactome.org/PathwayBrowser/#/R-MMU-190182 UROD decarboxylates URO1 to COPRO1 IEA Mus musculus 16526 R-MMU-191414 https://reactome.org/PathwayBrowser/#/R-MMU-191414 MVD decarboxylates MVA5PP to IPPP IEA Mus musculus 16526 R-MMU-194642 https://reactome.org/PathwayBrowser/#/R-MMU-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Mus musculus 16526 R-MMU-194718 https://reactome.org/PathwayBrowser/#/R-MMU-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Mus musculus 16526 R-MMU-196840 https://reactome.org/PathwayBrowser/#/R-MMU-196840 3xPPCDC:3FMN decarboxylates PPC IEA Mus musculus 16526 R-MMU-197268 https://reactome.org/PathwayBrowser/#/R-MMU-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Mus musculus 16526 R-MMU-1980233 https://reactome.org/PathwayBrowser/#/R-MMU-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Mus musculus 16526 R-MMU-1981104 https://reactome.org/PathwayBrowser/#/R-MMU-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Mus musculus 16526 R-MMU-2046083 https://reactome.org/PathwayBrowser/#/R-MMU-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Mus musculus 16526 R-MMU-2046088 https://reactome.org/PathwayBrowser/#/R-MMU-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Mus musculus 16526 R-MMU-2046090 https://reactome.org/PathwayBrowser/#/R-MMU-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 16526 R-MMU-2046094 https://reactome.org/PathwayBrowser/#/R-MMU-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Mus musculus 16526 R-MMU-2046095 https://reactome.org/PathwayBrowser/#/R-MMU-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Mus musculus 16526 R-MMU-2046100 https://reactome.org/PathwayBrowser/#/R-MMU-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Mus musculus 16526 R-MMU-209859 https://reactome.org/PathwayBrowser/#/R-MMU-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Mus musculus 16526 R-MMU-209924 https://reactome.org/PathwayBrowser/#/R-MMU-209924 Dopa is decarboxylated to dopamine IEA Mus musculus 16526 R-MMU-350598 https://reactome.org/PathwayBrowser/#/R-MMU-350598 Arginine<=>Agmatine+CO2 IEA Mus musculus 16526 R-MMU-351222 https://reactome.org/PathwayBrowser/#/R-MMU-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Mus musculus 16526 R-MMU-372819 https://reactome.org/PathwayBrowser/#/R-MMU-372819 PCK2 phosphorylates OA to yield PEP IEA Mus musculus 16526 R-MMU-389540 https://reactome.org/PathwayBrowser/#/R-MMU-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 16526 R-MMU-389550 https://reactome.org/PathwayBrowser/#/R-MMU-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 16526 R-MMU-389639 https://reactome.org/PathwayBrowser/#/R-MMU-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Mus musculus 16526 R-MMU-428127 https://reactome.org/PathwayBrowser/#/R-MMU-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Mus musculus 16526 R-MMU-450984 https://reactome.org/PathwayBrowser/#/R-MMU-450984 IDH2 dimer decarboxylates isocitrate IEA Mus musculus 16526 R-MMU-4722133 https://reactome.org/PathwayBrowser/#/R-MMU-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Mus musculus 16526 R-MMU-4724279 https://reactome.org/PathwayBrowser/#/R-MMU-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Mus musculus 16526 R-MMU-4724284 https://reactome.org/PathwayBrowser/#/R-MMU-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Mus musculus 16526 R-MMU-4754176 https://reactome.org/PathwayBrowser/#/R-MMU-4754176 JMJD6 demethylates MeR3-histone H3 IEA Mus musculus 16526 R-MMU-4754181 https://reactome.org/PathwayBrowser/#/R-MMU-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Mus musculus 16526 R-MMU-4754187 https://reactome.org/PathwayBrowser/#/R-MMU-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Mus musculus 16526 R-MMU-5220931 https://reactome.org/PathwayBrowser/#/R-MMU-5220931 Tet1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine TAS Mus musculus 16526 R-MMU-5220936 https://reactome.org/PathwayBrowser/#/R-MMU-5220936 Tet1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine TAS Mus musculus 16526 R-MMU-5220944 https://reactome.org/PathwayBrowser/#/R-MMU-5220944 Tet1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine TAS Mus musculus 16526 R-MMU-5423117 https://reactome.org/PathwayBrowser/#/R-MMU-5423117 PHF8 demethylates MeK21-histone H4 IEA Mus musculus 16526 R-MMU-548800 https://reactome.org/PathwayBrowser/#/R-MMU-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Mus musculus 16526 R-MMU-548814 https://reactome.org/PathwayBrowser/#/R-MMU-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Mus musculus 16526 R-MMU-548815 https://reactome.org/PathwayBrowser/#/R-MMU-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Mus musculus 16526 R-MMU-548848 https://reactome.org/PathwayBrowser/#/R-MMU-548848 lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4] TAS Mus musculus 16526 R-MMU-5661114 https://reactome.org/PathwayBrowser/#/R-MMU-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Mus musculus 16526 R-MMU-5661115 https://reactome.org/PathwayBrowser/#/R-MMU-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Mus musculus 16526 R-MMU-5661116 https://reactome.org/PathwayBrowser/#/R-MMU-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Mus musculus 16526 R-MMU-5661120 https://reactome.org/PathwayBrowser/#/R-MMU-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Mus musculus 16526 R-MMU-5661121 https://reactome.org/PathwayBrowser/#/R-MMU-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Mus musculus 16526 R-MMU-5661122 https://reactome.org/PathwayBrowser/#/R-MMU-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Mus musculus 16526 R-MMU-5661124 https://reactome.org/PathwayBrowser/#/R-MMU-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Mus musculus 16526 R-MMU-5661125 https://reactome.org/PathwayBrowser/#/R-MMU-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Mus musculus 16526 R-MMU-5693967 https://reactome.org/PathwayBrowser/#/R-MMU-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Mus musculus 16526 R-MMU-6787757 https://reactome.org/PathwayBrowser/#/R-MMU-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Mus musculus 16526 R-MMU-6807214 https://reactome.org/PathwayBrowser/#/R-MMU-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Mus musculus 16526 R-MMU-6808487 https://reactome.org/PathwayBrowser/#/R-MMU-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 16526 R-MMU-6808496 https://reactome.org/PathwayBrowser/#/R-MMU-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 16526 R-MMU-6814165 https://reactome.org/PathwayBrowser/#/R-MMU-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Mus musculus 16526 R-MMU-70241 https://reactome.org/PathwayBrowser/#/R-MMU-70241 PCK1 phosphorylates OA to yield PEP IEA Mus musculus 16526 R-MMU-70692 https://reactome.org/PathwayBrowser/#/R-MMU-70692 ornithine => putrescine + CO2 IEA Mus musculus 16526 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 16526 R-MMU-70893 https://reactome.org/PathwayBrowser/#/R-MMU-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Mus musculus 16526 R-MMU-70967 https://reactome.org/PathwayBrowser/#/R-MMU-70967 IDH3 complex decarboxylates isocitrate IEA Mus musculus 16526 R-MMU-71031 https://reactome.org/PathwayBrowser/#/R-MMU-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Mus musculus 16526 R-MMU-71037 https://reactome.org/PathwayBrowser/#/R-MMU-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Mus musculus 16526 R-MMU-71046 https://reactome.org/PathwayBrowser/#/R-MMU-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Mus musculus 16526 R-MMU-71163 https://reactome.org/PathwayBrowser/#/R-MMU-71163 HPD dioxygenates HPP IEA Mus musculus 16526 R-MMU-71241 https://reactome.org/PathwayBrowser/#/R-MMU-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Mus musculus 16526 R-MMU-71261 https://reactome.org/PathwayBrowser/#/R-MMU-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Mus musculus 16526 R-MMU-71299 https://reactome.org/PathwayBrowser/#/R-MMU-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Mus musculus 16526 R-MMU-71401 https://reactome.org/PathwayBrowser/#/R-MMU-71401 OGDH dimer decarboxylates 2-OG IEA Mus musculus 16526 R-MMU-73564 https://reactome.org/PathwayBrowser/#/R-MMU-73564 UMPS dimer decarboxylates OMP to UMP IEA Mus musculus 16526 R-MMU-73591 https://reactome.org/PathwayBrowser/#/R-MMU-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Mus musculus 16526 R-MMU-73620 https://reactome.org/PathwayBrowser/#/R-MMU-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Mus musculus 16526 R-MMU-73806 https://reactome.org/PathwayBrowser/#/R-MMU-73806 AIR + CO2 => CAIR IEA Mus musculus 16526 R-MMU-75872 https://reactome.org/PathwayBrowser/#/R-MMU-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Mus musculus 16526 R-MMU-8857692 https://reactome.org/PathwayBrowser/#/R-MMU-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Mus musculus 16526 R-MMU-888572 https://reactome.org/PathwayBrowser/#/R-MMU-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Mus musculus 16526 R-MMU-888577 https://reactome.org/PathwayBrowser/#/R-MMU-888577 Synthesis of GABA by GAD2 IEA Mus musculus 16526 R-MMU-9012016 https://reactome.org/PathwayBrowser/#/R-MMU-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Mus musculus 16526 R-MMU-9012036 https://reactome.org/PathwayBrowser/#/R-MMU-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Mus musculus 16526 R-MMU-9012268 https://reactome.org/PathwayBrowser/#/R-MMU-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Mus musculus 16526 R-MMU-9012349 https://reactome.org/PathwayBrowser/#/R-MMU-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Mus musculus 16526 R-MMU-9629578 https://reactome.org/PathwayBrowser/#/R-MMU-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Mus musculus 16526 R-MMU-9629591 https://reactome.org/PathwayBrowser/#/R-MMU-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Mus musculus 16526 R-MMU-9629869 https://reactome.org/PathwayBrowser/#/R-MMU-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Mus musculus 16526 R-MMU-9629888 https://reactome.org/PathwayBrowser/#/R-MMU-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Mus musculus 16526 R-MMU-9629946 https://reactome.org/PathwayBrowser/#/R-MMU-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Mus musculus 16526 R-MMU-9630022 https://reactome.org/PathwayBrowser/#/R-MMU-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Mus musculus 16526 R-MMU-9630769 https://reactome.org/PathwayBrowser/#/R-MMU-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Mus musculus 16526 R-MMU-9630967 https://reactome.org/PathwayBrowser/#/R-MMU-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Mus musculus 16526 R-MMU-9630993 https://reactome.org/PathwayBrowser/#/R-MMU-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Mus musculus 16526 R-MMU-977301 https://reactome.org/PathwayBrowser/#/R-MMU-977301 Histidine is decarboxylated to histamine IEA Mus musculus 16526 R-MMU-977317 https://reactome.org/PathwayBrowser/#/R-MMU-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Mus musculus 16526 R-MMU-9817463 https://reactome.org/PathwayBrowser/#/R-MMU-9817463 Tet3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 dimethylated on lysine-9 TAS Mus musculus 16526 R-MMU-9822448 https://reactome.org/PathwayBrowser/#/R-MMU-9822448 Kdm5b demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 16526 R-MMU-9822463 https://reactome.org/PathwayBrowser/#/R-MMU-9822463 Kdm5a demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 16526 R-MMU-9822924 https://reactome.org/PathwayBrowser/#/R-MMU-9822924 Kdm6b (Jmjd3) demethylates histone H3 trimethyllysine-27 (H3K27me3) TAS Mus musculus 16526 R-MMU-9822964 https://reactome.org/PathwayBrowser/#/R-MMU-9822964 Kdm6a (Utx) demethylates trimethylated histone H3 lysine-27 (H3K27me3) TAS Mus musculus 16526 R-MMU-9861660 https://reactome.org/PathwayBrowser/#/R-MMU-9861660 ME1 tetramer decarboxylates OA to PYR IEA Mus musculus 16526 R-MMU-9861734 https://reactome.org/PathwayBrowser/#/R-MMU-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Mus musculus 16526 R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 16526 R-PFA-1237042 https://reactome.org/PathwayBrowser/#/R-PFA-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Plasmodium falciparum 16526 R-PFA-1247649 https://reactome.org/PathwayBrowser/#/R-PFA-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Plasmodium falciparum 16526 R-PFA-1475022 https://reactome.org/PathwayBrowser/#/R-PFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Plasmodium falciparum 16526 R-PFA-1475026 https://reactome.org/PathwayBrowser/#/R-PFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Plasmodium falciparum 16526 R-PFA-1475028 https://reactome.org/PathwayBrowser/#/R-PFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Plasmodium falciparum 16526 R-PFA-1475032 https://reactome.org/PathwayBrowser/#/R-PFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Plasmodium falciparum 16526 R-PFA-1475435 https://reactome.org/PathwayBrowser/#/R-PFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Plasmodium falciparum 16526 R-PFA-1475436 https://reactome.org/PathwayBrowser/#/R-PFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Plasmodium falciparum 16526 R-PFA-189421 https://reactome.org/PathwayBrowser/#/R-PFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Plasmodium falciparum 16526 R-PFA-189425 https://reactome.org/PathwayBrowser/#/R-PFA-189425 UROD decarboxylates URO3 to COPRO3 IEA Plasmodium falciparum 16526 R-PFA-189442 https://reactome.org/PathwayBrowser/#/R-PFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Plasmodium falciparum 16526 R-PFA-190182 https://reactome.org/PathwayBrowser/#/R-PFA-190182 UROD decarboxylates URO1 to COPRO1 IEA Plasmodium falciparum 16526 R-PFA-196840 https://reactome.org/PathwayBrowser/#/R-PFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Plasmodium falciparum 16526 R-PFA-2046088 https://reactome.org/PathwayBrowser/#/R-PFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Plasmodium falciparum 16526 R-PFA-2046094 https://reactome.org/PathwayBrowser/#/R-PFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Plasmodium falciparum 16526 R-PFA-2172678 https://reactome.org/PathwayBrowser/#/R-PFA-2172678 PHF8 demethylates histone H4K20me1 IEA Plasmodium falciparum 16526 R-PFA-350598 https://reactome.org/PathwayBrowser/#/R-PFA-350598 Arginine<=>Agmatine+CO2 IEA Plasmodium falciparum 16526 R-PFA-450984 https://reactome.org/PathwayBrowser/#/R-PFA-450984 IDH2 dimer decarboxylates isocitrate IEA Plasmodium falciparum 16526 R-PFA-4724284 https://reactome.org/PathwayBrowser/#/R-PFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Plasmodium falciparum 16526 R-PFA-548800 https://reactome.org/PathwayBrowser/#/R-PFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Plasmodium falciparum 16526 R-PFA-548814 https://reactome.org/PathwayBrowser/#/R-PFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Plasmodium falciparum 16526 R-PFA-5661115 https://reactome.org/PathwayBrowser/#/R-PFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Plasmodium falciparum 16526 R-PFA-70692 https://reactome.org/PathwayBrowser/#/R-PFA-70692 ornithine => putrescine + CO2 IEA Plasmodium falciparum 16526 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 16526 R-PFA-71401 https://reactome.org/PathwayBrowser/#/R-PFA-71401 OGDH dimer decarboxylates 2-OG IEA Plasmodium falciparum 16526 R-RNO-1234164 https://reactome.org/PathwayBrowser/#/R-RNO-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Rattus norvegicus 16526 R-RNO-1234165 https://reactome.org/PathwayBrowser/#/R-RNO-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 16526 R-RNO-1234173 https://reactome.org/PathwayBrowser/#/R-RNO-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 16526 R-RNO-1234177 https://reactome.org/PathwayBrowser/#/R-RNO-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 16526 R-RNO-1234181 https://reactome.org/PathwayBrowser/#/R-RNO-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 16526 R-RNO-1237042 https://reactome.org/PathwayBrowser/#/R-RNO-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Rattus norvegicus 16526 R-RNO-1237045 https://reactome.org/PathwayBrowser/#/R-RNO-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Rattus norvegicus 16526 R-RNO-1237047 https://reactome.org/PathwayBrowser/#/R-RNO-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Rattus norvegicus 16526 R-RNO-1237059 https://reactome.org/PathwayBrowser/#/R-RNO-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Rattus norvegicus 16526 R-RNO-1237069 https://reactome.org/PathwayBrowser/#/R-RNO-1237069 RHAG transports CO2 from extracellular region to cytosol IEA Rattus norvegicus 16526 R-RNO-1237081 https://reactome.org/PathwayBrowser/#/R-RNO-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Rattus norvegicus 16526 R-RNO-1237325 https://reactome.org/PathwayBrowser/#/R-RNO-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Rattus norvegicus 16526 R-RNO-1247645 https://reactome.org/PathwayBrowser/#/R-RNO-1247645 RHAG transports CO2 from cytosol to extracellular region IEA Rattus norvegicus 16526 R-RNO-1247649 https://reactome.org/PathwayBrowser/#/R-RNO-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Rattus norvegicus 16526 R-RNO-1247668 https://reactome.org/PathwayBrowser/#/R-RNO-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Rattus norvegicus 16526 R-RNO-1475017 https://reactome.org/PathwayBrowser/#/R-RNO-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Rattus norvegicus 16526 R-RNO-1475022 https://reactome.org/PathwayBrowser/#/R-RNO-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Rattus norvegicus 16526 R-RNO-1475025 https://reactome.org/PathwayBrowser/#/R-RNO-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Rattus norvegicus 16526 R-RNO-1475026 https://reactome.org/PathwayBrowser/#/R-RNO-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Rattus norvegicus 16526 R-RNO-1475028 https://reactome.org/PathwayBrowser/#/R-RNO-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Rattus norvegicus 16526 R-RNO-1475032 https://reactome.org/PathwayBrowser/#/R-RNO-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Rattus norvegicus 16526 R-RNO-1475435 https://reactome.org/PathwayBrowser/#/R-RNO-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Rattus norvegicus 16526 R-RNO-1475436 https://reactome.org/PathwayBrowser/#/R-RNO-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Rattus norvegicus 16526 R-RNO-1483118 https://reactome.org/PathwayBrowser/#/R-RNO-1483118 PS is decarboxylated to PE by Pisd TAS Rattus norvegicus 16526 R-RNO-159752 https://reactome.org/PathwayBrowser/#/R-RNO-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Rattus norvegicus 16526 R-RNO-159761 https://reactome.org/PathwayBrowser/#/R-RNO-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Rattus norvegicus 16526 R-RNO-159795 https://reactome.org/PathwayBrowser/#/R-RNO-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Rattus norvegicus 16526 R-RNO-159803 https://reactome.org/PathwayBrowser/#/R-RNO-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Rattus norvegicus 16526 R-RNO-159819 https://reactome.org/PathwayBrowser/#/R-RNO-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Rattus norvegicus 16526 R-RNO-159826 https://reactome.org/PathwayBrowser/#/R-RNO-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Rattus norvegicus 16526 R-RNO-163820 https://reactome.org/PathwayBrowser/#/R-RNO-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Rattus norvegicus 16526 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus 16526 R-RNO-1655440 https://reactome.org/PathwayBrowser/#/R-RNO-1655440 PXLP-K305-Csad decarboxylates 3-sulfinoalanine to hypotaurine TAS Rattus norvegicus 16526 R-RNO-189421 https://reactome.org/PathwayBrowser/#/R-RNO-189421 CPO transforms COPRO3 to PPGEN9 IEA Rattus norvegicus 16526 R-RNO-189425 https://reactome.org/PathwayBrowser/#/R-RNO-189425 UROD decarboxylates URO3 to COPRO3 IEA Rattus norvegicus 16526 R-RNO-189442 https://reactome.org/PathwayBrowser/#/R-RNO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Rattus norvegicus 16526 R-RNO-190182 https://reactome.org/PathwayBrowser/#/R-RNO-190182 UROD decarboxylates URO1 to COPRO1 IEA Rattus norvegicus 16526 R-RNO-191414 https://reactome.org/PathwayBrowser/#/R-RNO-191414 MVD decarboxylates MVA5PP to IPPP IEA Rattus norvegicus 16526 R-RNO-194642 https://reactome.org/PathwayBrowser/#/R-RNO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Rattus norvegicus 16526 R-RNO-194718 https://reactome.org/PathwayBrowser/#/R-RNO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Rattus norvegicus 16526 R-RNO-196840 https://reactome.org/PathwayBrowser/#/R-RNO-196840 3xPPCDC:3FMN decarboxylates PPC IEA Rattus norvegicus 16526 R-RNO-197268 https://reactome.org/PathwayBrowser/#/R-RNO-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Rattus norvegicus 16526 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus 16526 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus 16526 R-RNO-2046083 https://reactome.org/PathwayBrowser/#/R-RNO-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Rattus norvegicus 16526 R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus 16526 R-RNO-2046090 https://reactome.org/PathwayBrowser/#/R-RNO-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 16526 R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus 16526 R-RNO-2046095 https://reactome.org/PathwayBrowser/#/R-RNO-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Rattus norvegicus 16526 R-RNO-2046100 https://reactome.org/PathwayBrowser/#/R-RNO-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Rattus norvegicus 16526 R-RNO-209859 https://reactome.org/PathwayBrowser/#/R-RNO-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Rattus norvegicus 16526 R-RNO-209924 https://reactome.org/PathwayBrowser/#/R-RNO-209924 Dopa is decarboxylated to dopamine IEA Rattus norvegicus 16526 R-RNO-2172678 https://reactome.org/PathwayBrowser/#/R-RNO-2172678 PHF8 demethylates histone H4K20me1 IEA Rattus norvegicus 16526 R-RNO-350598 https://reactome.org/PathwayBrowser/#/R-RNO-350598 Arginine<=>Agmatine+CO2 IEA Rattus norvegicus 16526 R-RNO-351222 https://reactome.org/PathwayBrowser/#/R-RNO-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Rattus norvegicus 16526 R-RNO-372819 https://reactome.org/PathwayBrowser/#/R-RNO-372819 PCK2 phosphorylates OA to yield PEP IEA Rattus norvegicus 16526 R-RNO-389540 https://reactome.org/PathwayBrowser/#/R-RNO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 16526 R-RNO-389550 https://reactome.org/PathwayBrowser/#/R-RNO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 16526 R-RNO-389639 https://reactome.org/PathwayBrowser/#/R-RNO-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Rattus norvegicus 16526 R-RNO-428127 https://reactome.org/PathwayBrowser/#/R-RNO-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Rattus norvegicus 16526 R-RNO-450984 https://reactome.org/PathwayBrowser/#/R-RNO-450984 IDH2 dimer decarboxylates isocitrate IEA Rattus norvegicus 16526 R-RNO-4722133 https://reactome.org/PathwayBrowser/#/R-RNO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Rattus norvegicus 16526 R-RNO-4724279 https://reactome.org/PathwayBrowser/#/R-RNO-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Rattus norvegicus 16526 R-RNO-4724284 https://reactome.org/PathwayBrowser/#/R-RNO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Rattus norvegicus 16526 R-RNO-4754176 https://reactome.org/PathwayBrowser/#/R-RNO-4754176 JMJD6 demethylates MeR3-histone H3 IEA Rattus norvegicus 16526 R-RNO-4754181 https://reactome.org/PathwayBrowser/#/R-RNO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Rattus norvegicus 16526 R-RNO-4754187 https://reactome.org/PathwayBrowser/#/R-RNO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Rattus norvegicus 16526 R-RNO-5423117 https://reactome.org/PathwayBrowser/#/R-RNO-5423117 PHF8 demethylates MeK21-histone H4 IEA Rattus norvegicus 16526 R-RNO-548800 https://reactome.org/PathwayBrowser/#/R-RNO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Rattus norvegicus 16526 R-RNO-548814 https://reactome.org/PathwayBrowser/#/R-RNO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Rattus norvegicus 16526 R-RNO-548815 https://reactome.org/PathwayBrowser/#/R-RNO-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Rattus norvegicus 16526 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 16526 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 16526 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 16526 R-RNO-5661114 https://reactome.org/PathwayBrowser/#/R-RNO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Rattus norvegicus 16526 R-RNO-5661115 https://reactome.org/PathwayBrowser/#/R-RNO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Rattus norvegicus 16526 R-RNO-5661116 https://reactome.org/PathwayBrowser/#/R-RNO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Rattus norvegicus 16526 R-RNO-5661120 https://reactome.org/PathwayBrowser/#/R-RNO-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Rattus norvegicus 16526 R-RNO-5661121 https://reactome.org/PathwayBrowser/#/R-RNO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Rattus norvegicus 16526 R-RNO-5661122 https://reactome.org/PathwayBrowser/#/R-RNO-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Rattus norvegicus 16526 R-RNO-5661124 https://reactome.org/PathwayBrowser/#/R-RNO-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Rattus norvegicus 16526 R-RNO-5661125 https://reactome.org/PathwayBrowser/#/R-RNO-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Rattus norvegicus 16526 R-RNO-5693967 https://reactome.org/PathwayBrowser/#/R-RNO-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Rattus norvegicus 16526 R-RNO-6787757 https://reactome.org/PathwayBrowser/#/R-RNO-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Rattus norvegicus 16526 R-RNO-6807214 https://reactome.org/PathwayBrowser/#/R-RNO-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Rattus norvegicus 16526 R-RNO-6808487 https://reactome.org/PathwayBrowser/#/R-RNO-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 16526 R-RNO-6808496 https://reactome.org/PathwayBrowser/#/R-RNO-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 16526 R-RNO-6814165 https://reactome.org/PathwayBrowser/#/R-RNO-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Rattus norvegicus 16526 R-RNO-70241 https://reactome.org/PathwayBrowser/#/R-RNO-70241 PCK1 phosphorylates OA to yield PEP IEA Rattus norvegicus 16526 R-RNO-70692 https://reactome.org/PathwayBrowser/#/R-RNO-70692 ornithine => putrescine + CO2 IEA Rattus norvegicus 16526 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 16526 R-RNO-70893 https://reactome.org/PathwayBrowser/#/R-RNO-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 16526 R-RNO-70967 https://reactome.org/PathwayBrowser/#/R-RNO-70967 IDH3 complex decarboxylates isocitrate IEA Rattus norvegicus 16526 R-RNO-71031 https://reactome.org/PathwayBrowser/#/R-RNO-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Rattus norvegicus 16526 R-RNO-71037 https://reactome.org/PathwayBrowser/#/R-RNO-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 16526 R-RNO-71046 https://reactome.org/PathwayBrowser/#/R-RNO-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Rattus norvegicus 16526 R-RNO-71163 https://reactome.org/PathwayBrowser/#/R-RNO-71163 HPD dioxygenates HPP IEA Rattus norvegicus 16526 R-RNO-71234 https://reactome.org/PathwayBrowser/#/R-RNO-71234 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 [rat] TAS Rattus norvegicus 16526 R-RNO-71241 https://reactome.org/PathwayBrowser/#/R-RNO-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Rattus norvegicus 16526 R-RNO-71261 https://reactome.org/PathwayBrowser/#/R-RNO-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Rattus norvegicus 16526 R-RNO-71299 https://reactome.org/PathwayBrowser/#/R-RNO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Rattus norvegicus 16526 R-RNO-71401 https://reactome.org/PathwayBrowser/#/R-RNO-71401 OGDH dimer decarboxylates 2-OG IEA Rattus norvegicus 16526 R-RNO-73564 https://reactome.org/PathwayBrowser/#/R-RNO-73564 UMPS dimer decarboxylates OMP to UMP IEA Rattus norvegicus 16526 R-RNO-73591 https://reactome.org/PathwayBrowser/#/R-RNO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Rattus norvegicus 16526 R-RNO-73620 https://reactome.org/PathwayBrowser/#/R-RNO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Rattus norvegicus 16526 R-RNO-73806 https://reactome.org/PathwayBrowser/#/R-RNO-73806 AIR + CO2 => CAIR IEA Rattus norvegicus 16526 R-RNO-75872 https://reactome.org/PathwayBrowser/#/R-RNO-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Rattus norvegicus 16526 R-RNO-8857692 https://reactome.org/PathwayBrowser/#/R-RNO-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Rattus norvegicus 16526 R-RNO-888572 https://reactome.org/PathwayBrowser/#/R-RNO-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Rattus norvegicus 16526 R-RNO-888577 https://reactome.org/PathwayBrowser/#/R-RNO-888577 Synthesis of GABA by GAD2 IEA Rattus norvegicus 16526 R-RNO-9012016 https://reactome.org/PathwayBrowser/#/R-RNO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Rattus norvegicus 16526 R-RNO-9012036 https://reactome.org/PathwayBrowser/#/R-RNO-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 16526 R-RNO-9012268 https://reactome.org/PathwayBrowser/#/R-RNO-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 16526 R-RNO-9012349 https://reactome.org/PathwayBrowser/#/R-RNO-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 16526 R-RNO-9629578 https://reactome.org/PathwayBrowser/#/R-RNO-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Rattus norvegicus 16526 R-RNO-9629591 https://reactome.org/PathwayBrowser/#/R-RNO-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Rattus norvegicus 16526 R-RNO-9629869 https://reactome.org/PathwayBrowser/#/R-RNO-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Rattus norvegicus 16526 R-RNO-9629888 https://reactome.org/PathwayBrowser/#/R-RNO-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Rattus norvegicus 16526 R-RNO-9629946 https://reactome.org/PathwayBrowser/#/R-RNO-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Rattus norvegicus 16526 R-RNO-9630022 https://reactome.org/PathwayBrowser/#/R-RNO-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Rattus norvegicus 16526 R-RNO-9630769 https://reactome.org/PathwayBrowser/#/R-RNO-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Rattus norvegicus 16526 R-RNO-9630967 https://reactome.org/PathwayBrowser/#/R-RNO-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Rattus norvegicus 16526 R-RNO-9630993 https://reactome.org/PathwayBrowser/#/R-RNO-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Rattus norvegicus 16526 R-RNO-977301 https://reactome.org/PathwayBrowser/#/R-RNO-977301 Histidine is decarboxylated to histamine IEA Rattus norvegicus 16526 R-RNO-977317 https://reactome.org/PathwayBrowser/#/R-RNO-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Rattus norvegicus 16526 R-RNO-9861660 https://reactome.org/PathwayBrowser/#/R-RNO-9861660 ME1 tetramer decarboxylates OA to PYR IEA Rattus norvegicus 16526 R-RNO-9861734 https://reactome.org/PathwayBrowser/#/R-RNO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Rattus norvegicus 16526 R-SCE-189421 https://reactome.org/PathwayBrowser/#/R-SCE-189421 CPO transforms COPRO3 to PPGEN9 IEA Saccharomyces cerevisiae 16526 R-SCE-189425 https://reactome.org/PathwayBrowser/#/R-SCE-189425 UROD decarboxylates URO3 to COPRO3 IEA Saccharomyces cerevisiae 16526 R-SCE-189442 https://reactome.org/PathwayBrowser/#/R-SCE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Saccharomyces cerevisiae 16526 R-SCE-190182 https://reactome.org/PathwayBrowser/#/R-SCE-190182 UROD decarboxylates URO1 to COPRO1 IEA Saccharomyces cerevisiae 16526 R-SCE-191414 https://reactome.org/PathwayBrowser/#/R-SCE-191414 MVD decarboxylates MVA5PP to IPPP IEA Saccharomyces cerevisiae 16526 R-SCE-194642 https://reactome.org/PathwayBrowser/#/R-SCE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Saccharomyces cerevisiae 16526 R-SCE-194718 https://reactome.org/PathwayBrowser/#/R-SCE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Saccharomyces cerevisiae 16526 R-SCE-196840 https://reactome.org/PathwayBrowser/#/R-SCE-196840 3xPPCDC:3FMN decarboxylates PPC IEA Saccharomyces cerevisiae 16526 R-SCE-197268 https://reactome.org/PathwayBrowser/#/R-SCE-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Saccharomyces cerevisiae 16526 R-SCE-2046088 https://reactome.org/PathwayBrowser/#/R-SCE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Saccharomyces cerevisiae 16526 R-SCE-2046094 https://reactome.org/PathwayBrowser/#/R-SCE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Saccharomyces cerevisiae 16526 R-SCE-2164816 https://reactome.org/PathwayBrowser/#/R-SCE-2164816 MHHB is decarboxylated to HMPhOH by MHHB decarboxylase TAS Saccharomyces cerevisiae 16526 R-SCE-2172678 https://reactome.org/PathwayBrowser/#/R-SCE-2172678 PHF8 demethylates histone H4K20me1 IEA Saccharomyces cerevisiae 16526 R-SCE-350598 https://reactome.org/PathwayBrowser/#/R-SCE-350598 Arginine<=>Agmatine+CO2 IEA Saccharomyces cerevisiae 16526 R-SCE-351222 https://reactome.org/PathwayBrowser/#/R-SCE-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Saccharomyces cerevisiae 16526 R-SCE-389540 https://reactome.org/PathwayBrowser/#/R-SCE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 16526 R-SCE-389550 https://reactome.org/PathwayBrowser/#/R-SCE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 16526 R-SCE-389639 https://reactome.org/PathwayBrowser/#/R-SCE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Saccharomyces cerevisiae 16526 R-SCE-4722133 https://reactome.org/PathwayBrowser/#/R-SCE-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Saccharomyces cerevisiae 16526 R-SCE-4724279 https://reactome.org/PathwayBrowser/#/R-SCE-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Saccharomyces cerevisiae 16526 R-SCE-4754181 https://reactome.org/PathwayBrowser/#/R-SCE-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Saccharomyces cerevisiae 16526 R-SCE-4754187 https://reactome.org/PathwayBrowser/#/R-SCE-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Saccharomyces cerevisiae 16526 R-SCE-548800 https://reactome.org/PathwayBrowser/#/R-SCE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Saccharomyces cerevisiae 16526 R-SCE-548814 https://reactome.org/PathwayBrowser/#/R-SCE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Saccharomyces cerevisiae 16526 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16526 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16526 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16526 R-SCE-5661114 https://reactome.org/PathwayBrowser/#/R-SCE-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Saccharomyces cerevisiae 16526 R-SCE-5661116 https://reactome.org/PathwayBrowser/#/R-SCE-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Saccharomyces cerevisiae 16526 R-SCE-5661120 https://reactome.org/PathwayBrowser/#/R-SCE-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Saccharomyces cerevisiae 16526 R-SCE-5661121 https://reactome.org/PathwayBrowser/#/R-SCE-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Saccharomyces cerevisiae 16526 R-SCE-5693967 https://reactome.org/PathwayBrowser/#/R-SCE-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Saccharomyces cerevisiae 16526 R-SCE-6783393 https://reactome.org/PathwayBrowser/#/R-SCE-6783393 PPM2 methoxycarbonylates yW-58 yielding yW at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 16526 R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 16526 R-SCE-70692 https://reactome.org/PathwayBrowser/#/R-SCE-70692 ornithine => putrescine + CO2 IEA Saccharomyces cerevisiae 16526 R-SCE-70967 https://reactome.org/PathwayBrowser/#/R-SCE-70967 IDH3 complex decarboxylates isocitrate IEA Saccharomyces cerevisiae 16526 R-SCE-71261 https://reactome.org/PathwayBrowser/#/R-SCE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Saccharomyces cerevisiae 16526 R-SCE-71299 https://reactome.org/PathwayBrowser/#/R-SCE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 16526 R-SCE-71401 https://reactome.org/PathwayBrowser/#/R-SCE-71401 OGDH dimer decarboxylates 2-OG IEA Saccharomyces cerevisiae 16526 R-SCE-9012016 https://reactome.org/PathwayBrowser/#/R-SCE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Saccharomyces cerevisiae 16526 R-SCE-9630769 https://reactome.org/PathwayBrowser/#/R-SCE-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Saccharomyces cerevisiae 16526 R-SCE-9861734 https://reactome.org/PathwayBrowser/#/R-SCE-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Saccharomyces cerevisiae 16526 R-SPO-189421 https://reactome.org/PathwayBrowser/#/R-SPO-189421 CPO transforms COPRO3 to PPGEN9 IEA Schizosaccharomyces pombe 16526 R-SPO-189425 https://reactome.org/PathwayBrowser/#/R-SPO-189425 UROD decarboxylates URO3 to COPRO3 IEA Schizosaccharomyces pombe 16526 R-SPO-189442 https://reactome.org/PathwayBrowser/#/R-SPO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Schizosaccharomyces pombe 16526 R-SPO-190182 https://reactome.org/PathwayBrowser/#/R-SPO-190182 UROD decarboxylates URO1 to COPRO1 IEA Schizosaccharomyces pombe 16526 R-SPO-191414 https://reactome.org/PathwayBrowser/#/R-SPO-191414 MVD decarboxylates MVA5PP to IPPP IEA Schizosaccharomyces pombe 16526 R-SPO-194642 https://reactome.org/PathwayBrowser/#/R-SPO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Schizosaccharomyces pombe 16526 R-SPO-194718 https://reactome.org/PathwayBrowser/#/R-SPO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Schizosaccharomyces pombe 16526 R-SPO-2046088 https://reactome.org/PathwayBrowser/#/R-SPO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Schizosaccharomyces pombe 16526 R-SPO-2046094 https://reactome.org/PathwayBrowser/#/R-SPO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Schizosaccharomyces pombe 16526 R-SPO-2172678 https://reactome.org/PathwayBrowser/#/R-SPO-2172678 PHF8 demethylates histone H4K20me1 IEA Schizosaccharomyces pombe 16526 R-SPO-350598 https://reactome.org/PathwayBrowser/#/R-SPO-350598 Arginine<=>Agmatine+CO2 IEA Schizosaccharomyces pombe 16526 R-SPO-351222 https://reactome.org/PathwayBrowser/#/R-SPO-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Schizosaccharomyces pombe 16526 R-SPO-389540 https://reactome.org/PathwayBrowser/#/R-SPO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 16526 R-SPO-389550 https://reactome.org/PathwayBrowser/#/R-SPO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 16526 R-SPO-4722133 https://reactome.org/PathwayBrowser/#/R-SPO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Schizosaccharomyces pombe 16526 R-SPO-4724284 https://reactome.org/PathwayBrowser/#/R-SPO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Schizosaccharomyces pombe 16526 R-SPO-4754181 https://reactome.org/PathwayBrowser/#/R-SPO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Schizosaccharomyces pombe 16526 R-SPO-4754187 https://reactome.org/PathwayBrowser/#/R-SPO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Schizosaccharomyces pombe 16526 R-SPO-5423117 https://reactome.org/PathwayBrowser/#/R-SPO-5423117 PHF8 demethylates MeK21-histone H4 IEA Schizosaccharomyces pombe 16526 R-SPO-548800 https://reactome.org/PathwayBrowser/#/R-SPO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Schizosaccharomyces pombe 16526 R-SPO-548814 https://reactome.org/PathwayBrowser/#/R-SPO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Schizosaccharomyces pombe 16526 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16526 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16526 R-SPO-5661114 https://reactome.org/PathwayBrowser/#/R-SPO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Schizosaccharomyces pombe 16526 R-SPO-5661115 https://reactome.org/PathwayBrowser/#/R-SPO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Schizosaccharomyces pombe 16526 R-SPO-5661116 https://reactome.org/PathwayBrowser/#/R-SPO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Schizosaccharomyces pombe 16526 R-SPO-5661121 https://reactome.org/PathwayBrowser/#/R-SPO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Schizosaccharomyces pombe 16526 R-SPO-5693967 https://reactome.org/PathwayBrowser/#/R-SPO-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Schizosaccharomyces pombe 16526 R-SPO-70692 https://reactome.org/PathwayBrowser/#/R-SPO-70692 ornithine => putrescine + CO2 IEA Schizosaccharomyces pombe 16526 R-SPO-70967 https://reactome.org/PathwayBrowser/#/R-SPO-70967 IDH3 complex decarboxylates isocitrate IEA Schizosaccharomyces pombe 16526 R-SPO-71299 https://reactome.org/PathwayBrowser/#/R-SPO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 16526 R-SPO-71401 https://reactome.org/PathwayBrowser/#/R-SPO-71401 OGDH dimer decarboxylates 2-OG IEA Schizosaccharomyces pombe 16526 R-SPO-73591 https://reactome.org/PathwayBrowser/#/R-SPO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Schizosaccharomyces pombe 16526 R-SPO-73620 https://reactome.org/PathwayBrowser/#/R-SPO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Schizosaccharomyces pombe 16526 R-SPO-9012016 https://reactome.org/PathwayBrowser/#/R-SPO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Schizosaccharomyces pombe 16526 R-SPO-9629946 https://reactome.org/PathwayBrowser/#/R-SPO-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Schizosaccharomyces pombe 16526 R-SPO-9630769 https://reactome.org/PathwayBrowser/#/R-SPO-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Schizosaccharomyces pombe 16526 R-SPO-9861734 https://reactome.org/PathwayBrowser/#/R-SPO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Schizosaccharomyces pombe 16526 R-SSC-1234164 https://reactome.org/PathwayBrowser/#/R-SSC-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Sus scrofa 16526 R-SSC-1234165 https://reactome.org/PathwayBrowser/#/R-SSC-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 16526 R-SSC-1234173 https://reactome.org/PathwayBrowser/#/R-SSC-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 16526 R-SSC-1234177 https://reactome.org/PathwayBrowser/#/R-SSC-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 16526 R-SSC-1234181 https://reactome.org/PathwayBrowser/#/R-SSC-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 16526 R-SSC-1237042 https://reactome.org/PathwayBrowser/#/R-SSC-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Sus scrofa 16526 R-SSC-1237045 https://reactome.org/PathwayBrowser/#/R-SSC-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Sus scrofa 16526 R-SSC-1237047 https://reactome.org/PathwayBrowser/#/R-SSC-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Sus scrofa 16526 R-SSC-1237059 https://reactome.org/PathwayBrowser/#/R-SSC-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Sus scrofa 16526 R-SSC-1237069 https://reactome.org/PathwayBrowser/#/R-SSC-1237069 RHAG transports CO2 from extracellular region to cytosol IEA Sus scrofa 16526 R-SSC-1237081 https://reactome.org/PathwayBrowser/#/R-SSC-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Sus scrofa 16526 R-SSC-1237325 https://reactome.org/PathwayBrowser/#/R-SSC-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Sus scrofa 16526 R-SSC-1247645 https://reactome.org/PathwayBrowser/#/R-SSC-1247645 RHAG transports CO2 from cytosol to extracellular region IEA Sus scrofa 16526 R-SSC-1247649 https://reactome.org/PathwayBrowser/#/R-SSC-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Sus scrofa 16526 R-SSC-1247668 https://reactome.org/PathwayBrowser/#/R-SSC-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Sus scrofa 16526 R-SSC-1475017 https://reactome.org/PathwayBrowser/#/R-SSC-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Sus scrofa 16526 R-SSC-1475022 https://reactome.org/PathwayBrowser/#/R-SSC-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Sus scrofa 16526 R-SSC-1475025 https://reactome.org/PathwayBrowser/#/R-SSC-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Sus scrofa 16526 R-SSC-1475026 https://reactome.org/PathwayBrowser/#/R-SSC-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Sus scrofa 16526 R-SSC-1475028 https://reactome.org/PathwayBrowser/#/R-SSC-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Sus scrofa 16526 R-SSC-1475032 https://reactome.org/PathwayBrowser/#/R-SSC-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Sus scrofa 16526 R-SSC-1475435 https://reactome.org/PathwayBrowser/#/R-SSC-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Sus scrofa 16526 R-SSC-1475436 https://reactome.org/PathwayBrowser/#/R-SSC-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Sus scrofa 16526 R-SSC-159752 https://reactome.org/PathwayBrowser/#/R-SSC-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Sus scrofa 16526 R-SSC-159761 https://reactome.org/PathwayBrowser/#/R-SSC-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Sus scrofa 16526 R-SSC-159795 https://reactome.org/PathwayBrowser/#/R-SSC-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Sus scrofa 16526 R-SSC-159803 https://reactome.org/PathwayBrowser/#/R-SSC-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Sus scrofa 16526 R-SSC-159819 https://reactome.org/PathwayBrowser/#/R-SSC-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Sus scrofa 16526 R-SSC-159826 https://reactome.org/PathwayBrowser/#/R-SSC-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Sus scrofa 16526 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa 16526 R-SSC-189421 https://reactome.org/PathwayBrowser/#/R-SSC-189421 CPO transforms COPRO3 to PPGEN9 IEA Sus scrofa 16526 R-SSC-189425 https://reactome.org/PathwayBrowser/#/R-SSC-189425 UROD decarboxylates URO3 to COPRO3 IEA Sus scrofa 16526 R-SSC-189442 https://reactome.org/PathwayBrowser/#/R-SSC-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Sus scrofa 16526 R-SSC-190182 https://reactome.org/PathwayBrowser/#/R-SSC-190182 UROD decarboxylates URO1 to COPRO1 IEA Sus scrofa 16526 R-SSC-191414 https://reactome.org/PathwayBrowser/#/R-SSC-191414 MVD decarboxylates MVA5PP to IPPP IEA Sus scrofa 16526 R-SSC-194642 https://reactome.org/PathwayBrowser/#/R-SSC-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Sus scrofa 16526 R-SSC-194718 https://reactome.org/PathwayBrowser/#/R-SSC-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Sus scrofa 16526 R-SSC-196840 https://reactome.org/PathwayBrowser/#/R-SSC-196840 3xPPCDC:3FMN decarboxylates PPC IEA Sus scrofa 16526 R-SSC-197268 https://reactome.org/PathwayBrowser/#/R-SSC-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Sus scrofa 16526 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa 16526 R-SSC-2046083 https://reactome.org/PathwayBrowser/#/R-SSC-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Sus scrofa 16526 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa 16526 R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 16526 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa 16526 R-SSC-2046095 https://reactome.org/PathwayBrowser/#/R-SSC-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Sus scrofa 16526 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa 16526 R-SSC-209859 https://reactome.org/PathwayBrowser/#/R-SSC-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Sus scrofa 16526 R-SSC-209924 https://reactome.org/PathwayBrowser/#/R-SSC-209924 Dopa is decarboxylated to dopamine IEA Sus scrofa 16526 R-SSC-2172678 https://reactome.org/PathwayBrowser/#/R-SSC-2172678 PHF8 demethylates histone H4K20me1 IEA Sus scrofa 16526 R-SSC-350598 https://reactome.org/PathwayBrowser/#/R-SSC-350598 Arginine<=>Agmatine+CO2 IEA Sus scrofa 16526 R-SSC-351222 https://reactome.org/PathwayBrowser/#/R-SSC-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Sus scrofa 16526 R-SSC-372819 https://reactome.org/PathwayBrowser/#/R-SSC-372819 PCK2 phosphorylates OA to yield PEP IEA Sus scrofa 16526 R-SSC-389540 https://reactome.org/PathwayBrowser/#/R-SSC-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 16526 R-SSC-389550 https://reactome.org/PathwayBrowser/#/R-SSC-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 16526 R-SSC-389639 https://reactome.org/PathwayBrowser/#/R-SSC-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Sus scrofa 16526 R-SSC-428127 https://reactome.org/PathwayBrowser/#/R-SSC-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Sus scrofa 16526 R-SSC-450984 https://reactome.org/PathwayBrowser/#/R-SSC-450984 IDH2 dimer decarboxylates isocitrate IEA Sus scrofa 16526 R-SSC-4722133 https://reactome.org/PathwayBrowser/#/R-SSC-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Sus scrofa 16526 R-SSC-4724279 https://reactome.org/PathwayBrowser/#/R-SSC-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Sus scrofa 16526 R-SSC-4724284 https://reactome.org/PathwayBrowser/#/R-SSC-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Sus scrofa 16526 R-SSC-4754176 https://reactome.org/PathwayBrowser/#/R-SSC-4754176 JMJD6 demethylates MeR3-histone H3 IEA Sus scrofa 16526 R-SSC-4754181 https://reactome.org/PathwayBrowser/#/R-SSC-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Sus scrofa 16526 R-SSC-4754187 https://reactome.org/PathwayBrowser/#/R-SSC-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Sus scrofa 16526 R-SSC-5423117 https://reactome.org/PathwayBrowser/#/R-SSC-5423117 PHF8 demethylates MeK21-histone H4 IEA Sus scrofa 16526 R-SSC-548800 https://reactome.org/PathwayBrowser/#/R-SSC-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Sus scrofa 16526 R-SSC-548814 https://reactome.org/PathwayBrowser/#/R-SSC-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Sus scrofa 16526 R-SSC-548815 https://reactome.org/PathwayBrowser/#/R-SSC-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Sus scrofa 16526 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 16526 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 16526 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 16526 R-SSC-5661114 https://reactome.org/PathwayBrowser/#/R-SSC-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Sus scrofa 16526 R-SSC-5661115 https://reactome.org/PathwayBrowser/#/R-SSC-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Sus scrofa 16526 R-SSC-5661116 https://reactome.org/PathwayBrowser/#/R-SSC-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Sus scrofa 16526 R-SSC-5661120 https://reactome.org/PathwayBrowser/#/R-SSC-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Sus scrofa 16526 R-SSC-5661121 https://reactome.org/PathwayBrowser/#/R-SSC-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Sus scrofa 16526 R-SSC-5661122 https://reactome.org/PathwayBrowser/#/R-SSC-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Sus scrofa 16526 R-SSC-5661124 https://reactome.org/PathwayBrowser/#/R-SSC-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Sus scrofa 16526 R-SSC-5661125 https://reactome.org/PathwayBrowser/#/R-SSC-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Sus scrofa 16526 R-SSC-5693967 https://reactome.org/PathwayBrowser/#/R-SSC-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Sus scrofa 16526 R-SSC-6787757 https://reactome.org/PathwayBrowser/#/R-SSC-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Sus scrofa 16526 R-SSC-6807214 https://reactome.org/PathwayBrowser/#/R-SSC-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Sus scrofa 16526 R-SSC-6808487 https://reactome.org/PathwayBrowser/#/R-SSC-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 16526 R-SSC-6808496 https://reactome.org/PathwayBrowser/#/R-SSC-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 16526 R-SSC-6814165 https://reactome.org/PathwayBrowser/#/R-SSC-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Sus scrofa 16526 R-SSC-70241 https://reactome.org/PathwayBrowser/#/R-SSC-70241 PCK1 phosphorylates OA to yield PEP IEA Sus scrofa 16526 R-SSC-70692 https://reactome.org/PathwayBrowser/#/R-SSC-70692 ornithine => putrescine + CO2 IEA Sus scrofa 16526 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 16526 R-SSC-70893 https://reactome.org/PathwayBrowser/#/R-SSC-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Sus scrofa 16526 R-SSC-70967 https://reactome.org/PathwayBrowser/#/R-SSC-70967 IDH3 complex decarboxylates isocitrate IEA Sus scrofa 16526 R-SSC-71031 https://reactome.org/PathwayBrowser/#/R-SSC-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Sus scrofa 16526 R-SSC-71037 https://reactome.org/PathwayBrowser/#/R-SSC-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Sus scrofa 16526 R-SSC-71046 https://reactome.org/PathwayBrowser/#/R-SSC-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Sus scrofa 16526 R-SSC-71163 https://reactome.org/PathwayBrowser/#/R-SSC-71163 HPD dioxygenates HPP IEA Sus scrofa 16526 R-SSC-71241 https://reactome.org/PathwayBrowser/#/R-SSC-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Sus scrofa 16526 R-SSC-71261 https://reactome.org/PathwayBrowser/#/R-SSC-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Sus scrofa 16526 R-SSC-71299 https://reactome.org/PathwayBrowser/#/R-SSC-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Sus scrofa 16526 R-SSC-71401 https://reactome.org/PathwayBrowser/#/R-SSC-71401 OGDH dimer decarboxylates 2-OG IEA Sus scrofa 16526 R-SSC-73564 https://reactome.org/PathwayBrowser/#/R-SSC-73564 UMPS dimer decarboxylates OMP to UMP IEA Sus scrofa 16526 R-SSC-73591 https://reactome.org/PathwayBrowser/#/R-SSC-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Sus scrofa 16526 R-SSC-73620 https://reactome.org/PathwayBrowser/#/R-SSC-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Sus scrofa 16526 R-SSC-73806 https://reactome.org/PathwayBrowser/#/R-SSC-73806 AIR + CO2 => CAIR IEA Sus scrofa 16526 R-SSC-75872 https://reactome.org/PathwayBrowser/#/R-SSC-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Sus scrofa 16526 R-SSC-8857692 https://reactome.org/PathwayBrowser/#/R-SSC-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Sus scrofa 16526 R-SSC-888572 https://reactome.org/PathwayBrowser/#/R-SSC-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Sus scrofa 16526 R-SSC-888577 https://reactome.org/PathwayBrowser/#/R-SSC-888577 Synthesis of GABA by GAD2 IEA Sus scrofa 16526 R-SSC-9012016 https://reactome.org/PathwayBrowser/#/R-SSC-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Sus scrofa 16526 R-SSC-9012036 https://reactome.org/PathwayBrowser/#/R-SSC-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Sus scrofa 16526 R-SSC-9012268 https://reactome.org/PathwayBrowser/#/R-SSC-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Sus scrofa 16526 R-SSC-9012349 https://reactome.org/PathwayBrowser/#/R-SSC-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Sus scrofa 16526 R-SSC-9629578 https://reactome.org/PathwayBrowser/#/R-SSC-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Sus scrofa 16526 R-SSC-9629591 https://reactome.org/PathwayBrowser/#/R-SSC-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Sus scrofa 16526 R-SSC-9629869 https://reactome.org/PathwayBrowser/#/R-SSC-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Sus scrofa 16526 R-SSC-9629888 https://reactome.org/PathwayBrowser/#/R-SSC-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Sus scrofa 16526 R-SSC-9629946 https://reactome.org/PathwayBrowser/#/R-SSC-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Sus scrofa 16526 R-SSC-9630022 https://reactome.org/PathwayBrowser/#/R-SSC-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Sus scrofa 16526 R-SSC-9630769 https://reactome.org/PathwayBrowser/#/R-SSC-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Sus scrofa 16526 R-SSC-9630967 https://reactome.org/PathwayBrowser/#/R-SSC-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Sus scrofa 16526 R-SSC-9630993 https://reactome.org/PathwayBrowser/#/R-SSC-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Sus scrofa 16526 R-SSC-977301 https://reactome.org/PathwayBrowser/#/R-SSC-977301 Histidine is decarboxylated to histamine IEA Sus scrofa 16526 R-SSC-977317 https://reactome.org/PathwayBrowser/#/R-SSC-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Sus scrofa 16526 R-SSC-9861660 https://reactome.org/PathwayBrowser/#/R-SSC-9861660 ME1 tetramer decarboxylates OA to PYR IEA Sus scrofa 16526 R-SSC-9861734 https://reactome.org/PathwayBrowser/#/R-SSC-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Sus scrofa 16526 R-XTR-1234164 https://reactome.org/PathwayBrowser/#/R-XTR-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Xenopus tropicalis 16526 R-XTR-1234165 https://reactome.org/PathwayBrowser/#/R-XTR-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 16526 R-XTR-1234173 https://reactome.org/PathwayBrowser/#/R-XTR-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 16526 R-XTR-1234177 https://reactome.org/PathwayBrowser/#/R-XTR-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 16526 R-XTR-1234181 https://reactome.org/PathwayBrowser/#/R-XTR-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 16526 R-XTR-1237042 https://reactome.org/PathwayBrowser/#/R-XTR-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Xenopus tropicalis 16526 R-XTR-1237047 https://reactome.org/PathwayBrowser/#/R-XTR-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Xenopus tropicalis 16526 R-XTR-1237059 https://reactome.org/PathwayBrowser/#/R-XTR-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Xenopus tropicalis 16526 R-XTR-1237069 https://reactome.org/PathwayBrowser/#/R-XTR-1237069 RHAG transports CO2 from extracellular region to cytosol IEA Xenopus tropicalis 16526 R-XTR-1237325 https://reactome.org/PathwayBrowser/#/R-XTR-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Xenopus tropicalis 16526 R-XTR-1247645 https://reactome.org/PathwayBrowser/#/R-XTR-1247645 RHAG transports CO2 from cytosol to extracellular region IEA Xenopus tropicalis 16526 R-XTR-1247649 https://reactome.org/PathwayBrowser/#/R-XTR-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Xenopus tropicalis 16526 R-XTR-1247668 https://reactome.org/PathwayBrowser/#/R-XTR-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Xenopus tropicalis 16526 R-XTR-1475017 https://reactome.org/PathwayBrowser/#/R-XTR-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Xenopus tropicalis 16526 R-XTR-1475022 https://reactome.org/PathwayBrowser/#/R-XTR-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Xenopus tropicalis 16526 R-XTR-1475025 https://reactome.org/PathwayBrowser/#/R-XTR-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Xenopus tropicalis 16526 R-XTR-1475026 https://reactome.org/PathwayBrowser/#/R-XTR-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Xenopus tropicalis 16526 R-XTR-1475028 https://reactome.org/PathwayBrowser/#/R-XTR-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Xenopus tropicalis 16526 R-XTR-1475032 https://reactome.org/PathwayBrowser/#/R-XTR-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Xenopus tropicalis 16526 R-XTR-1475435 https://reactome.org/PathwayBrowser/#/R-XTR-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Xenopus tropicalis 16526 R-XTR-1475436 https://reactome.org/PathwayBrowser/#/R-XTR-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Xenopus tropicalis 16526 R-XTR-159752 https://reactome.org/PathwayBrowser/#/R-XTR-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Xenopus tropicalis 16526 R-XTR-159761 https://reactome.org/PathwayBrowser/#/R-XTR-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Xenopus tropicalis 16526 R-XTR-159795 https://reactome.org/PathwayBrowser/#/R-XTR-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Xenopus tropicalis 16526 R-XTR-159803 https://reactome.org/PathwayBrowser/#/R-XTR-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Xenopus tropicalis 16526 R-XTR-159819 https://reactome.org/PathwayBrowser/#/R-XTR-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Xenopus tropicalis 16526 R-XTR-159826 https://reactome.org/PathwayBrowser/#/R-XTR-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Xenopus tropicalis 16526 R-XTR-163820 https://reactome.org/PathwayBrowser/#/R-XTR-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Xenopus tropicalis 16526 R-XTR-1650808 https://reactome.org/PathwayBrowser/#/R-XTR-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Xenopus tropicalis 16526 R-XTR-189421 https://reactome.org/PathwayBrowser/#/R-XTR-189421 CPO transforms COPRO3 to PPGEN9 IEA Xenopus tropicalis 16526 R-XTR-189425 https://reactome.org/PathwayBrowser/#/R-XTR-189425 UROD decarboxylates URO3 to COPRO3 IEA Xenopus tropicalis 16526 R-XTR-189442 https://reactome.org/PathwayBrowser/#/R-XTR-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Xenopus tropicalis 16526 R-XTR-190182 https://reactome.org/PathwayBrowser/#/R-XTR-190182 UROD decarboxylates URO1 to COPRO1 IEA Xenopus tropicalis 16526 R-XTR-191414 https://reactome.org/PathwayBrowser/#/R-XTR-191414 MVD decarboxylates MVA5PP to IPPP IEA Xenopus tropicalis 16526 R-XTR-196840 https://reactome.org/PathwayBrowser/#/R-XTR-196840 3xPPCDC:3FMN decarboxylates PPC IEA Xenopus tropicalis 16526 R-XTR-197268 https://reactome.org/PathwayBrowser/#/R-XTR-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Xenopus tropicalis 16526 R-XTR-1980233 https://reactome.org/PathwayBrowser/#/R-XTR-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Xenopus tropicalis 16526 R-XTR-1981104 https://reactome.org/PathwayBrowser/#/R-XTR-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Xenopus tropicalis 16526 R-XTR-2046083 https://reactome.org/PathwayBrowser/#/R-XTR-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Xenopus tropicalis 16526 R-XTR-2046088 https://reactome.org/PathwayBrowser/#/R-XTR-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Xenopus tropicalis 16526 R-XTR-2046090 https://reactome.org/PathwayBrowser/#/R-XTR-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Xenopus tropicalis 16526 R-XTR-2046094 https://reactome.org/PathwayBrowser/#/R-XTR-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Xenopus tropicalis 16526 R-XTR-2046095 https://reactome.org/PathwayBrowser/#/R-XTR-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Xenopus tropicalis 16526 R-XTR-2046100 https://reactome.org/PathwayBrowser/#/R-XTR-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Xenopus tropicalis 16526 R-XTR-209859 https://reactome.org/PathwayBrowser/#/R-XTR-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Xenopus tropicalis 16526 R-XTR-209924 https://reactome.org/PathwayBrowser/#/R-XTR-209924 Dopa is decarboxylated to dopamine IEA Xenopus tropicalis 16526 R-XTR-2172678 https://reactome.org/PathwayBrowser/#/R-XTR-2172678 PHF8 demethylates histone H4K20me1 IEA Xenopus tropicalis 16526 R-XTR-351222 https://reactome.org/PathwayBrowser/#/R-XTR-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Xenopus tropicalis 16526 R-XTR-389540 https://reactome.org/PathwayBrowser/#/R-XTR-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 16526 R-XTR-389550 https://reactome.org/PathwayBrowser/#/R-XTR-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 16526 R-XTR-389639 https://reactome.org/PathwayBrowser/#/R-XTR-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Xenopus tropicalis 16526 R-XTR-428127 https://reactome.org/PathwayBrowser/#/R-XTR-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Xenopus tropicalis 16526 R-XTR-450984 https://reactome.org/PathwayBrowser/#/R-XTR-450984 IDH2 dimer decarboxylates isocitrate IEA Xenopus tropicalis 16526 R-XTR-548800 https://reactome.org/PathwayBrowser/#/R-XTR-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Xenopus tropicalis 16526 R-XTR-548814 https://reactome.org/PathwayBrowser/#/R-XTR-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Xenopus tropicalis 16526 R-XTR-548815 https://reactome.org/PathwayBrowser/#/R-XTR-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Xenopus tropicalis 16526 R-XTR-6787757 https://reactome.org/PathwayBrowser/#/R-XTR-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Xenopus tropicalis 16526 R-XTR-6807214 https://reactome.org/PathwayBrowser/#/R-XTR-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Xenopus tropicalis 16526 R-XTR-6808487 https://reactome.org/PathwayBrowser/#/R-XTR-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 16526 R-XTR-6808496 https://reactome.org/PathwayBrowser/#/R-XTR-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 16526 R-XTR-6814165 https://reactome.org/PathwayBrowser/#/R-XTR-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Xenopus tropicalis 16526 R-XTR-70241 https://reactome.org/PathwayBrowser/#/R-XTR-70241 PCK1 phosphorylates OA to yield PEP IEA Xenopus tropicalis 16526 R-XTR-70692 https://reactome.org/PathwayBrowser/#/R-XTR-70692 ornithine => putrescine + CO2 IEA Xenopus tropicalis 16526 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 16526 R-XTR-70893 https://reactome.org/PathwayBrowser/#/R-XTR-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 16526 R-XTR-71031 https://reactome.org/PathwayBrowser/#/R-XTR-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Xenopus tropicalis 16526 R-XTR-71037 https://reactome.org/PathwayBrowser/#/R-XTR-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 16526 R-XTR-71046 https://reactome.org/PathwayBrowser/#/R-XTR-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Xenopus tropicalis 16526 R-XTR-71163 https://reactome.org/PathwayBrowser/#/R-XTR-71163 HPD dioxygenates HPP IEA Xenopus tropicalis 16526 R-XTR-71241 https://reactome.org/PathwayBrowser/#/R-XTR-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Xenopus tropicalis 16526 R-XTR-71261 https://reactome.org/PathwayBrowser/#/R-XTR-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Xenopus tropicalis 16526 R-XTR-71401 https://reactome.org/PathwayBrowser/#/R-XTR-71401 OGDH dimer decarboxylates 2-OG IEA Xenopus tropicalis 16526 R-XTR-73564 https://reactome.org/PathwayBrowser/#/R-XTR-73564 UMPS dimer decarboxylates OMP to UMP IEA Xenopus tropicalis 16526 R-XTR-73806 https://reactome.org/PathwayBrowser/#/R-XTR-73806 AIR + CO2 => CAIR IEA Xenopus tropicalis 16526 R-XTR-75872 https://reactome.org/PathwayBrowser/#/R-XTR-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Xenopus tropicalis 16526 R-XTR-8857692 https://reactome.org/PathwayBrowser/#/R-XTR-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Xenopus tropicalis 16526 R-XTR-888572 https://reactome.org/PathwayBrowser/#/R-XTR-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Xenopus tropicalis 16526 R-XTR-888577 https://reactome.org/PathwayBrowser/#/R-XTR-888577 Synthesis of GABA by GAD2 IEA Xenopus tropicalis 16526 R-XTR-9012016 https://reactome.org/PathwayBrowser/#/R-XTR-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Xenopus tropicalis 16526 R-XTR-9012268 https://reactome.org/PathwayBrowser/#/R-XTR-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 16526 R-XTR-9012349 https://reactome.org/PathwayBrowser/#/R-XTR-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 16526 R-XTR-9629578 https://reactome.org/PathwayBrowser/#/R-XTR-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Xenopus tropicalis 16526 R-XTR-9629591 https://reactome.org/PathwayBrowser/#/R-XTR-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Xenopus tropicalis 16526 R-XTR-9629869 https://reactome.org/PathwayBrowser/#/R-XTR-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Xenopus tropicalis 16526 R-XTR-9629888 https://reactome.org/PathwayBrowser/#/R-XTR-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Xenopus tropicalis 16526 R-XTR-9630022 https://reactome.org/PathwayBrowser/#/R-XTR-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Xenopus tropicalis 16526 R-XTR-9630769 https://reactome.org/PathwayBrowser/#/R-XTR-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Xenopus tropicalis 16526 R-XTR-9630993 https://reactome.org/PathwayBrowser/#/R-XTR-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Xenopus tropicalis 16526 R-XTR-977301 https://reactome.org/PathwayBrowser/#/R-XTR-977301 Histidine is decarboxylated to histamine IEA Xenopus tropicalis 16526 R-XTR-977317 https://reactome.org/PathwayBrowser/#/R-XTR-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Xenopus tropicalis 16526 R-XTR-9861734 https://reactome.org/PathwayBrowser/#/R-XTR-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Xenopus tropicalis 16530 R-BTA-508189 https://reactome.org/PathwayBrowser/#/R-BTA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Bos taurus 16530 R-BTA-70723 https://reactome.org/PathwayBrowser/#/R-BTA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Bos taurus 16530 R-CEL-508189 https://reactome.org/PathwayBrowser/#/R-CEL-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Caenorhabditis elegans 16530 R-CEL-70723 https://reactome.org/PathwayBrowser/#/R-CEL-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Caenorhabditis elegans 16530 R-CFA-508189 https://reactome.org/PathwayBrowser/#/R-CFA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Canis familiaris 16530 R-CFA-70723 https://reactome.org/PathwayBrowser/#/R-CFA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Canis familiaris 16530 R-DDI-508189 https://reactome.org/PathwayBrowser/#/R-DDI-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Dictyostelium discoideum 16530 R-DDI-70723 https://reactome.org/PathwayBrowser/#/R-DDI-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Dictyostelium discoideum 16530 R-DME-508189 https://reactome.org/PathwayBrowser/#/R-DME-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Drosophila melanogaster 16530 R-DME-70723 https://reactome.org/PathwayBrowser/#/R-DME-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Drosophila melanogaster 16530 R-DRE-508189 https://reactome.org/PathwayBrowser/#/R-DRE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Danio rerio 16530 R-DRE-70723 https://reactome.org/PathwayBrowser/#/R-DRE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Danio rerio 16530 R-GGA-508189 https://reactome.org/PathwayBrowser/#/R-GGA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Gallus gallus 16530 R-GGA-70723 https://reactome.org/PathwayBrowser/#/R-GGA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Gallus gallus 16530 R-HSA-508189 https://reactome.org/PathwayBrowser/#/R-HSA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] TAS Homo sapiens 16530 R-HSA-70723 https://reactome.org/PathwayBrowser/#/R-HSA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] TAS Homo sapiens 16530 R-MMU-508189 https://reactome.org/PathwayBrowser/#/R-MMU-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Mus musculus 16530 R-MMU-70723 https://reactome.org/PathwayBrowser/#/R-MMU-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Mus musculus 16530 R-RNO-508189 https://reactome.org/PathwayBrowser/#/R-RNO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Rattus norvegicus 16530 R-RNO-70723 https://reactome.org/PathwayBrowser/#/R-RNO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Rattus norvegicus 16530 R-SCE-508189 https://reactome.org/PathwayBrowser/#/R-SCE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Saccharomyces cerevisiae 16530 R-SCE-70723 https://reactome.org/PathwayBrowser/#/R-SCE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Saccharomyces cerevisiae 16530 R-SPO-508189 https://reactome.org/PathwayBrowser/#/R-SPO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Schizosaccharomyces pombe 16530 R-SPO-70723 https://reactome.org/PathwayBrowser/#/R-SPO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Schizosaccharomyces pombe 16530 R-SSC-508189 https://reactome.org/PathwayBrowser/#/R-SSC-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Sus scrofa 16530 R-SSC-70723 https://reactome.org/PathwayBrowser/#/R-SSC-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Sus scrofa 16530 R-XTR-508189 https://reactome.org/PathwayBrowser/#/R-XTR-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Xenopus tropicalis 16530 R-XTR-70723 https://reactome.org/PathwayBrowser/#/R-XTR-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Xenopus tropicalis 16541 R-BTA-1678841 https://reactome.org/PathwayBrowser/#/R-BTA-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Bos taurus 16541 R-BTA-5419271 https://reactome.org/PathwayBrowser/#/R-BTA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Bos taurus 16541 R-CEL-1678841 https://reactome.org/PathwayBrowser/#/R-CEL-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Caenorhabditis elegans 16541 R-CEL-5419271 https://reactome.org/PathwayBrowser/#/R-CEL-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Caenorhabditis elegans 16541 R-CFA-1678841 https://reactome.org/PathwayBrowser/#/R-CFA-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Canis familiaris 16541 R-CFA-5419271 https://reactome.org/PathwayBrowser/#/R-CFA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Canis familiaris 16541 R-DME-1678841 https://reactome.org/PathwayBrowser/#/R-DME-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Drosophila melanogaster 16541 R-DME-5419271 https://reactome.org/PathwayBrowser/#/R-DME-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Drosophila melanogaster 16541 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Gallus gallus 16541 R-HSA-1678841 https://reactome.org/PathwayBrowser/#/R-HSA-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 TAS Homo sapiens 16541 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 16541 R-MMU-1678841 https://reactome.org/PathwayBrowser/#/R-MMU-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Mus musculus 16541 R-MMU-5419271 https://reactome.org/PathwayBrowser/#/R-MMU-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Mus musculus 16541 R-RNO-1678841 https://reactome.org/PathwayBrowser/#/R-RNO-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Rattus norvegicus 16541 R-RNO-5419271 https://reactome.org/PathwayBrowser/#/R-RNO-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Rattus norvegicus 16541 R-SCE-141698 https://reactome.org/PathwayBrowser/#/R-SCE-141698 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex TAS Saccharomyces cerevisiae 16541 R-SSC-1678841 https://reactome.org/PathwayBrowser/#/R-SSC-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Sus scrofa 16541 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Sus scrofa 16551 R-HSA-188985 https://reactome.org/PathwayBrowser/#/R-HSA-188985 trehalose + H2O => 2 D-glucose IEA Homo sapiens 16551 R-MTU-868608 https://reactome.org/PathwayBrowser/#/R-MTU-868608 Trehalose-6-phosphate is hydrolyzed to trehalose TAS Mycobacterium tuberculosis 16551 R-MTU-868657 https://reactome.org/PathwayBrowser/#/R-MTU-868657 Glucanotrehalose is hydrolyzed to 1,4-alpha-glucan and trehalose TAS Mycobacterium tuberculosis 16551 R-MTU-868709 https://reactome.org/PathwayBrowser/#/R-MTU-868709 Maltose is converted to trehalose TAS Mycobacterium tuberculosis 16551 R-OCU-189019 https://reactome.org/PathwayBrowser/#/R-OCU-189019 trehalose + H2O => 2 D-glucose TAS Oryctolagus cuniculus 16566 R-GGA-433576 https://reactome.org/PathwayBrowser/#/R-GGA-433576 3-dehydrosphinganine + NADPH + H+ => sphinganine + NADP+ IEA Gallus gallus 16566 R-GGA-433592 https://reactome.org/PathwayBrowser/#/R-GGA-433592 sphinganine + stearyl-CoA => dihydroceramide + CoASH IEA Gallus gallus 16566 R-GGA-433606 https://reactome.org/PathwayBrowser/#/R-GGA-433606 sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP IEA Gallus gallus 16577 R-BTA-193407 https://reactome.org/PathwayBrowser/#/R-BTA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 16577 R-BTA-193424 https://reactome.org/PathwayBrowser/#/R-BTA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 16577 R-BTA-193460 https://reactome.org/PathwayBrowser/#/R-BTA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Bos taurus 16577 R-CEL-193407 https://reactome.org/PathwayBrowser/#/R-CEL-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 16577 R-CEL-193424 https://reactome.org/PathwayBrowser/#/R-CEL-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 16577 R-CFA-193407 https://reactome.org/PathwayBrowser/#/R-CFA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 16577 R-CFA-193424 https://reactome.org/PathwayBrowser/#/R-CFA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 16577 R-CFA-193460 https://reactome.org/PathwayBrowser/#/R-CFA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Canis familiaris 16577 R-DME-193407 https://reactome.org/PathwayBrowser/#/R-DME-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 16577 R-DME-193424 https://reactome.org/PathwayBrowser/#/R-DME-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 16577 R-DRE-193407 https://reactome.org/PathwayBrowser/#/R-DRE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 16577 R-GGA-193407 https://reactome.org/PathwayBrowser/#/R-GGA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 16577 R-GGA-193424 https://reactome.org/PathwayBrowser/#/R-GGA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 16577 R-HSA-193407 https://reactome.org/PathwayBrowser/#/R-HSA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 16577 R-HSA-193424 https://reactome.org/PathwayBrowser/#/R-HSA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 16577 R-HSA-193460 https://reactome.org/PathwayBrowser/#/R-HSA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) TAS Homo sapiens 16577 R-HSA-193519 https://reactome.org/PathwayBrowser/#/R-HSA-193519 DHCA is translocated from the mitochondrial matrix to the cytosol TAS Homo sapiens 16577 R-MMU-193407 https://reactome.org/PathwayBrowser/#/R-MMU-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 16577 R-MMU-193424 https://reactome.org/PathwayBrowser/#/R-MMU-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 16577 R-MMU-193460 https://reactome.org/PathwayBrowser/#/R-MMU-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Mus musculus 16577 R-RNO-193407 https://reactome.org/PathwayBrowser/#/R-RNO-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 16577 R-RNO-193424 https://reactome.org/PathwayBrowser/#/R-RNO-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 16577 R-RNO-193460 https://reactome.org/PathwayBrowser/#/R-RNO-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Rattus norvegicus 16577 R-SCE-193407 https://reactome.org/PathwayBrowser/#/R-SCE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 16577 R-SCE-193424 https://reactome.org/PathwayBrowser/#/R-SCE-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 16577 R-SSC-193407 https://reactome.org/PathwayBrowser/#/R-SSC-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 16577 R-SSC-193424 https://reactome.org/PathwayBrowser/#/R-SSC-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 16577 R-SSC-193460 https://reactome.org/PathwayBrowser/#/R-SSC-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Sus scrofa 16577 R-XTR-193407 https://reactome.org/PathwayBrowser/#/R-XTR-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 16577 R-XTR-193424 https://reactome.org/PathwayBrowser/#/R-XTR-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 16580 R-BTA-158860 https://reactome.org/PathwayBrowser/#/R-BTA-158860 SULT1A1 dimer sulfonates NHABP IEA Bos taurus 16580 R-BTA-174963 https://reactome.org/PathwayBrowser/#/R-BTA-174963 NAT1 acetylation IEA Bos taurus 16580 R-BTA-174967 https://reactome.org/PathwayBrowser/#/R-BTA-174967 NAT2 acetylation IEA Bos taurus 16580 R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 16580 R-CFA-158860 https://reactome.org/PathwayBrowser/#/R-CFA-158860 SULT1A1 dimer sulfonates NHABP IEA Canis familiaris 16580 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 16580 R-DME-158860 https://reactome.org/PathwayBrowser/#/R-DME-158860 SULT1A1 dimer sulfonates NHABP IEA Drosophila melanogaster 16580 R-DRE-158860 https://reactome.org/PathwayBrowser/#/R-DRE-158860 SULT1A1 dimer sulfonates NHABP IEA Danio rerio 16580 R-DRE-174963 https://reactome.org/PathwayBrowser/#/R-DRE-174963 NAT1 acetylation IEA Danio rerio 16580 R-DRE-174967 https://reactome.org/PathwayBrowser/#/R-DRE-174967 NAT2 acetylation IEA Danio rerio 16580 R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 16580 R-GGA-158860 https://reactome.org/PathwayBrowser/#/R-GGA-158860 SULT1A1 dimer sulfonates NHABP IEA Gallus gallus 16580 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 16580 R-GGA-174963 https://reactome.org/PathwayBrowser/#/R-GGA-174963 NAT1 acetylation IEA Gallus gallus 16580 R-GGA-174967 https://reactome.org/PathwayBrowser/#/R-GGA-174967 NAT2 acetylation IEA Gallus gallus 16580 R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 16580 R-HSA-158860 https://reactome.org/PathwayBrowser/#/R-HSA-158860 SULT1A1 dimer sulfonates NHABP TAS Homo sapiens 16580 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 16580 R-HSA-174963 https://reactome.org/PathwayBrowser/#/R-HSA-174963 NAT1 acetylation TAS Homo sapiens 16580 R-HSA-174967 https://reactome.org/PathwayBrowser/#/R-HSA-174967 NAT2 acetylation TAS Homo sapiens 16580 R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 16580 R-MMU-158860 https://reactome.org/PathwayBrowser/#/R-MMU-158860 SULT1A1 dimer sulfonates NHABP IEA Mus musculus 16580 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 16580 R-MMU-174963 https://reactome.org/PathwayBrowser/#/R-MMU-174963 NAT1 acetylation IEA Mus musculus 16580 R-MMU-174967 https://reactome.org/PathwayBrowser/#/R-MMU-174967 NAT2 acetylation IEA Mus musculus 16580 R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 16580 R-RNO-158860 https://reactome.org/PathwayBrowser/#/R-RNO-158860 SULT1A1 dimer sulfonates NHABP IEA Rattus norvegicus 16580 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 16580 R-RNO-174963 https://reactome.org/PathwayBrowser/#/R-RNO-174963 NAT1 acetylation IEA Rattus norvegicus 16580 R-RNO-174967 https://reactome.org/PathwayBrowser/#/R-RNO-174967 NAT2 acetylation IEA Rattus norvegicus 16580 R-RNO-76373 https://reactome.org/PathwayBrowser/#/R-RNO-76373 N-hydroxylation of 4-aminobiphenyl IEA Rattus norvegicus 16580 R-SSC-158860 https://reactome.org/PathwayBrowser/#/R-SSC-158860 SULT1A1 dimer sulfonates NHABP IEA Sus scrofa 16580 R-SSC-174963 https://reactome.org/PathwayBrowser/#/R-SSC-174963 NAT1 acetylation IEA Sus scrofa 16580 R-SSC-174967 https://reactome.org/PathwayBrowser/#/R-SSC-174967 NAT2 acetylation IEA Sus scrofa 16580 R-SSC-76373 https://reactome.org/PathwayBrowser/#/R-SSC-76373 N-hydroxylation of 4-aminobiphenyl IEA Sus scrofa 16580 R-XTR-158860 https://reactome.org/PathwayBrowser/#/R-XTR-158860 SULT1A1 dimer sulfonates NHABP IEA Xenopus tropicalis 16581 R-BTA-176517 https://reactome.org/PathwayBrowser/#/R-BTA-176517 SULTs transfer (SO4)2- group to PREG IEA Bos taurus 16581 R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 16581 R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 16581 R-BTA-196350 https://reactome.org/PathwayBrowser/#/R-BTA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Bos taurus 16581 R-CFA-176517 https://reactome.org/PathwayBrowser/#/R-CFA-176517 SULTs transfer (SO4)2- group to PREG IEA Canis familiaris 16581 R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 16581 R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 16581 R-CFA-196350 https://reactome.org/PathwayBrowser/#/R-CFA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Canis familiaris 16581 R-DME-176517 https://reactome.org/PathwayBrowser/#/R-DME-176517 SULTs transfer (SO4)2- group to PREG IEA Drosophila melanogaster 16581 R-DRE-176517 https://reactome.org/PathwayBrowser/#/R-DRE-176517 SULTs transfer (SO4)2- group to PREG IEA Danio rerio 16581 R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 16581 R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 16581 R-DRE-196350 https://reactome.org/PathwayBrowser/#/R-DRE-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Danio rerio 16581 R-GGA-176517 https://reactome.org/PathwayBrowser/#/R-GGA-176517 SULTs transfer (SO4)2- group to PREG IEA Gallus gallus 16581 R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 16581 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 16581 R-GGA-196350 https://reactome.org/PathwayBrowser/#/R-GGA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Gallus gallus 16581 R-HSA-176517 https://reactome.org/PathwayBrowser/#/R-HSA-176517 SULTs transfer (SO4)2- group to PREG TAS Homo sapiens 16581 R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 16581 R-HSA-193097 https://reactome.org/PathwayBrowser/#/R-HSA-193097 Pregnenolone translocates from the mitochondrial matrix to the cytosol TAS Homo sapiens 16581 R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 16581 R-HSA-196350 https://reactome.org/PathwayBrowser/#/R-HSA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione TAS Homo sapiens 16581 R-HSA-5601843 https://reactome.org/PathwayBrowser/#/R-HSA-5601843 Defective CYP17A1 does not 17-hydroxylate PREG TAS Homo sapiens 16581 R-MMU-176517 https://reactome.org/PathwayBrowser/#/R-MMU-176517 SULTs transfer (SO4)2- group to PREG IEA Mus musculus 16581 R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 16581 R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 16581 R-MMU-196350 https://reactome.org/PathwayBrowser/#/R-MMU-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Mus musculus 16581 R-RNO-176517 https://reactome.org/PathwayBrowser/#/R-RNO-176517 SULTs transfer (SO4)2- group to PREG IEA Rattus norvegicus 16581 R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 16581 R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 16581 R-RNO-196350 https://reactome.org/PathwayBrowser/#/R-RNO-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Rattus norvegicus 16581 R-SSC-176517 https://reactome.org/PathwayBrowser/#/R-SSC-176517 SULTs transfer (SO4)2- group to PREG IEA Sus scrofa 16581 R-SSC-193068 https://reactome.org/PathwayBrowser/#/R-SSC-193068 CYP17A1 17-hydroxylates PREG IEA Sus scrofa 16581 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 16581 R-SSC-196350 https://reactome.org/PathwayBrowser/#/R-SSC-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Sus scrofa 16581 R-XTR-176517 https://reactome.org/PathwayBrowser/#/R-XTR-176517 SULTs transfer (SO4)2- group to PREG IEA Xenopus tropicalis 16581 R-XTR-193068 https://reactome.org/PathwayBrowser/#/R-XTR-193068 CYP17A1 17-hydroxylates PREG IEA Xenopus tropicalis 16581 R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 16608 R-BTA-6807052 https://reactome.org/PathwayBrowser/#/R-BTA-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Bos taurus 16608 R-BTA-6807064 https://reactome.org/PathwayBrowser/#/R-BTA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Bos taurus 16608 R-CEL-6807064 https://reactome.org/PathwayBrowser/#/R-CEL-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Caenorhabditis elegans 16608 R-CFA-6807052 https://reactome.org/PathwayBrowser/#/R-CFA-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Canis familiaris 16608 R-CFA-6807064 https://reactome.org/PathwayBrowser/#/R-CFA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Canis familiaris 16608 R-DDI-6807052 https://reactome.org/PathwayBrowser/#/R-DDI-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Dictyostelium discoideum 16608 R-DRE-6807052 https://reactome.org/PathwayBrowser/#/R-DRE-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Danio rerio 16608 R-DRE-6807064 https://reactome.org/PathwayBrowser/#/R-DRE-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Danio rerio 16608 R-GGA-6807052 https://reactome.org/PathwayBrowser/#/R-GGA-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Gallus gallus 16608 R-GGA-6807064 https://reactome.org/PathwayBrowser/#/R-GGA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Gallus gallus 16608 R-HSA-6807052 https://reactome.org/PathwayBrowser/#/R-HSA-6807052 EBP isomerizes ZYMSTNL to LTHSOL TAS Homo sapiens 16608 R-HSA-6807064 https://reactome.org/PathwayBrowser/#/R-HSA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL TAS Homo sapiens 16608 R-MMU-6807052 https://reactome.org/PathwayBrowser/#/R-MMU-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Mus musculus 16608 R-MMU-6807064 https://reactome.org/PathwayBrowser/#/R-MMU-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Mus musculus 16608 R-RNO-6807052 https://reactome.org/PathwayBrowser/#/R-RNO-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Rattus norvegicus 16608 R-RNO-6807064 https://reactome.org/PathwayBrowser/#/R-RNO-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Rattus norvegicus 16608 R-SSC-6807052 https://reactome.org/PathwayBrowser/#/R-SSC-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Sus scrofa 16608 R-SSC-6807064 https://reactome.org/PathwayBrowser/#/R-SSC-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Sus scrofa 16608 R-XTR-6807064 https://reactome.org/PathwayBrowser/#/R-XTR-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Xenopus tropicalis 16624 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 16624 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 16624 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 16624 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 16624 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 16624 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 16624 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 16624 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 16624 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 16624 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 16624 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 16624 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 16624 R-HSA-379974 https://reactome.org/PathwayBrowser/#/R-HSA-379974 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 16624 R-HSA-380200 https://reactome.org/PathwayBrowser/#/R-HSA-380200 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 16624 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 16624 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 16624 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 16624 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 16624 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 16624 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 16630 R-MTU-964842 https://reactome.org/PathwayBrowser/#/R-MTU-964842 Shikimate results from hydration of DHS TAS Mycobacterium tuberculosis 16630 R-MTU-964851 https://reactome.org/PathwayBrowser/#/R-MTU-964851 Dehydratation of DHQ yields DHS TAS Mycobacterium tuberculosis 16633 R-BTA-2408524 https://reactome.org/PathwayBrowser/#/R-BTA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Bos taurus 16633 R-CEL-2408524 https://reactome.org/PathwayBrowser/#/R-CEL-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Caenorhabditis elegans 16633 R-CFA-2408524 https://reactome.org/PathwayBrowser/#/R-CFA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Canis familiaris 16633 R-DRE-2408524 https://reactome.org/PathwayBrowser/#/R-DRE-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Danio rerio 16633 R-GGA-2408524 https://reactome.org/PathwayBrowser/#/R-GGA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Gallus gallus 16633 R-HSA-2408524 https://reactome.org/PathwayBrowser/#/R-HSA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer TAS Homo sapiens 16633 R-HSA-2408543 https://reactome.org/PathwayBrowser/#/R-HSA-2408543 SeCysta is hydrolysed to Sec by PXLP-K212-CTH IEA Homo sapiens 16633 R-HSA-5333615 https://reactome.org/PathwayBrowser/#/R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC IEA Homo sapiens 16633 R-MMU-2408524 https://reactome.org/PathwayBrowser/#/R-MMU-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Mus musculus 16633 R-RNO-2408502 https://reactome.org/PathwayBrowser/#/R-RNO-2408502 SeCysta is hydrolysed to Sec by PXLP-K211-Cth TAS Rattus norvegicus 16633 R-RNO-2408524 https://reactome.org/PathwayBrowser/#/R-RNO-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Rattus norvegicus 16633 R-RNO-5333610 https://reactome.org/PathwayBrowser/#/R-RNO-5333610 Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec-tRNA(Sec):Eefsec:GTP is hydrolysed to Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec and Eefsec:GDP by Eefsec TAS Rattus norvegicus 16633 R-SSC-2408524 https://reactome.org/PathwayBrowser/#/R-SSC-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Sus scrofa 16633 R-XTR-2408524 https://reactome.org/PathwayBrowser/#/R-XTR-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Xenopus tropicalis 16635 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 16635 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 16635 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 16635 R-BTA-5432520 https://reactome.org/PathwayBrowser/#/R-BTA-5432520 MTFMT formylates methionyl-tRNA TAS Bos taurus 16635 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 16635 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 16635 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 16635 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 16635 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 16635 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 16635 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 16635 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 16635 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 16635 R-HSA-379994 https://reactome.org/PathwayBrowser/#/R-HSA-379994 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 16635 R-HSA-380157 https://reactome.org/PathwayBrowser/#/R-HSA-380157 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 16635 R-HSA-5389841 https://reactome.org/PathwayBrowser/#/R-HSA-5389841 MTFMT formylates methionyl-tRNA IEA Homo sapiens 16635 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 16635 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 16635 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 16635 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 16635 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 16635 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 16651 R-BTA-373867 https://reactome.org/PathwayBrowser/#/R-BTA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Bos taurus 16651 R-BTA-373875 https://reactome.org/PathwayBrowser/#/R-BTA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Bos taurus 16651 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Bos taurus 16651 R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 16651 R-BTA-561253 https://reactome.org/PathwayBrowser/#/R-BTA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Bos taurus 16651 R-BTA-70510 https://reactome.org/PathwayBrowser/#/R-BTA-70510 LDH tetramer oxidises LACT to PYR IEA Bos taurus 16651 R-BTA-71849 https://reactome.org/PathwayBrowser/#/R-BTA-71849 LDH tetramer reduces PYR to LACT IEA Bos taurus 16651 R-BTA-8876312 https://reactome.org/PathwayBrowser/#/R-BTA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Bos taurus 16651 R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 16651 R-CEL-373867 https://reactome.org/PathwayBrowser/#/R-CEL-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 16651 R-CEL-373875 https://reactome.org/PathwayBrowser/#/R-CEL-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Caenorhabditis elegans 16651 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Caenorhabditis elegans 16651 R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 16651 R-CEL-561253 https://reactome.org/PathwayBrowser/#/R-CEL-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Caenorhabditis elegans 16651 R-CEL-70510 https://reactome.org/PathwayBrowser/#/R-CEL-70510 LDH tetramer oxidises LACT to PYR IEA Caenorhabditis elegans 16651 R-CEL-71849 https://reactome.org/PathwayBrowser/#/R-CEL-71849 LDH tetramer reduces PYR to LACT IEA Caenorhabditis elegans 16651 R-CEL-8876312 https://reactome.org/PathwayBrowser/#/R-CEL-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Caenorhabditis elegans 16651 R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 16651 R-CFA-373867 https://reactome.org/PathwayBrowser/#/R-CFA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Canis familiaris 16651 R-CFA-373875 https://reactome.org/PathwayBrowser/#/R-CFA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Canis familiaris 16651 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Canis familiaris 16651 R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 16651 R-CFA-561253 https://reactome.org/PathwayBrowser/#/R-CFA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Canis familiaris 16651 R-CFA-70510 https://reactome.org/PathwayBrowser/#/R-CFA-70510 LDH tetramer oxidises LACT to PYR IEA Canis familiaris 16651 R-CFA-71849 https://reactome.org/PathwayBrowser/#/R-CFA-71849 LDH tetramer reduces PYR to LACT IEA Canis familiaris 16651 R-CFA-8876312 https://reactome.org/PathwayBrowser/#/R-CFA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Canis familiaris 16651 R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 16651 R-DME-373867 https://reactome.org/PathwayBrowser/#/R-DME-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Drosophila melanogaster 16651 R-DME-373875 https://reactome.org/PathwayBrowser/#/R-DME-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Drosophila melanogaster 16651 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Drosophila melanogaster 16651 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 16651 R-DME-561253 https://reactome.org/PathwayBrowser/#/R-DME-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Drosophila melanogaster 16651 R-DME-70510 https://reactome.org/PathwayBrowser/#/R-DME-70510 LDH tetramer oxidises LACT to PYR IEA Drosophila melanogaster 16651 R-DME-71849 https://reactome.org/PathwayBrowser/#/R-DME-71849 LDH tetramer reduces PYR to LACT IEA Drosophila melanogaster 16651 R-DME-8876312 https://reactome.org/PathwayBrowser/#/R-DME-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Drosophila melanogaster 16651 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 16651 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Danio rerio 16651 R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 16651 R-DRE-70510 https://reactome.org/PathwayBrowser/#/R-DRE-70510 LDH tetramer oxidises LACT to PYR IEA Danio rerio 16651 R-DRE-71849 https://reactome.org/PathwayBrowser/#/R-DRE-71849 LDH tetramer reduces PYR to LACT IEA Danio rerio 16651 R-DRE-8876312 https://reactome.org/PathwayBrowser/#/R-DRE-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Danio rerio 16651 R-GGA-372903 https://reactome.org/PathwayBrowser/#/R-GGA-372903 lactate + NAD+ <=> pyruvate + NADH + H+ TAS Gallus gallus 16651 R-GGA-372910 https://reactome.org/PathwayBrowser/#/R-GGA-372910 pyruvate + NADH + H+ <=> lactate + NAD+ TAS Gallus gallus 16651 R-GGA-373867 https://reactome.org/PathwayBrowser/#/R-GGA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Gallus gallus 16651 R-GGA-373875 https://reactome.org/PathwayBrowser/#/R-GGA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Gallus gallus 16651 R-GGA-373887 https://reactome.org/PathwayBrowser/#/R-GGA-373887 lactate + H+ [extracellular] <=> lactate + H+ [cytosol] IEA Gallus gallus 16651 R-GGA-373889 https://reactome.org/PathwayBrowser/#/R-GGA-373889 lactate + H+ [cytosol] <=> lactate + H+ [extracellular] IEA Gallus gallus 16651 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Gallus gallus 16651 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 16651 R-GGA-70510 https://reactome.org/PathwayBrowser/#/R-GGA-70510 LDH tetramer oxidises LACT to PYR IEA Gallus gallus 16651 R-GGA-71849 https://reactome.org/PathwayBrowser/#/R-GGA-71849 LDH tetramer reduces PYR to LACT IEA Gallus gallus 16651 R-GGA-8876312 https://reactome.org/PathwayBrowser/#/R-GGA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Gallus gallus 16651 R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 16651 R-HSA-373867 https://reactome.org/PathwayBrowser/#/R-HSA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol TAS Homo sapiens 16651 R-HSA-373875 https://reactome.org/PathwayBrowser/#/R-HSA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region TAS Homo sapiens 16651 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol TAS Homo sapiens 16651 R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 16651 R-HSA-561253 https://reactome.org/PathwayBrowser/#/R-HSA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT TAS Homo sapiens 16651 R-HSA-5625210 https://reactome.org/PathwayBrowser/#/R-HSA-5625210 Defective SLC22A12 does not exchange extracellular urate for cytosolic LACT TAS Homo sapiens 16651 R-HSA-70510 https://reactome.org/PathwayBrowser/#/R-HSA-70510 LDH tetramer oxidises LACT to PYR TAS Homo sapiens 16651 R-HSA-71849 https://reactome.org/PathwayBrowser/#/R-HSA-71849 LDH tetramer reduces PYR to LACT TAS Homo sapiens 16651 R-HSA-8876312 https://reactome.org/PathwayBrowser/#/R-HSA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol TAS Homo sapiens 16651 R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 16651 R-MMU-373867 https://reactome.org/PathwayBrowser/#/R-MMU-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Mus musculus 16651 R-MMU-373875 https://reactome.org/PathwayBrowser/#/R-MMU-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Mus musculus 16651 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Mus musculus 16651 R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 16651 R-MMU-561253 https://reactome.org/PathwayBrowser/#/R-MMU-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Mus musculus 16651 R-MMU-70510 https://reactome.org/PathwayBrowser/#/R-MMU-70510 LDH tetramer oxidises LACT to PYR IEA Mus musculus 16651 R-MMU-71849 https://reactome.org/PathwayBrowser/#/R-MMU-71849 LDH tetramer reduces PYR to LACT IEA Mus musculus 16651 R-MMU-8876312 https://reactome.org/PathwayBrowser/#/R-MMU-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Mus musculus 16651 R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 16651 R-RNO-373867 https://reactome.org/PathwayBrowser/#/R-RNO-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Rattus norvegicus 16651 R-RNO-373875 https://reactome.org/PathwayBrowser/#/R-RNO-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Rattus norvegicus 16651 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Rattus norvegicus 16651 R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 16651 R-RNO-561253 https://reactome.org/PathwayBrowser/#/R-RNO-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Rattus norvegicus 16651 R-RNO-70510 https://reactome.org/PathwayBrowser/#/R-RNO-70510 LDH tetramer oxidises LACT to PYR IEA Rattus norvegicus 16651 R-RNO-71849 https://reactome.org/PathwayBrowser/#/R-RNO-71849 LDH tetramer reduces PYR to LACT IEA Rattus norvegicus 16651 R-RNO-8876312 https://reactome.org/PathwayBrowser/#/R-RNO-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Rattus norvegicus 16651 R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 16651 R-SSC-373867 https://reactome.org/PathwayBrowser/#/R-SSC-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Sus scrofa 16651 R-SSC-373875 https://reactome.org/PathwayBrowser/#/R-SSC-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Sus scrofa 16651 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Sus scrofa 16651 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 16651 R-SSC-561253 https://reactome.org/PathwayBrowser/#/R-SSC-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Sus scrofa 16651 R-SSC-70510 https://reactome.org/PathwayBrowser/#/R-SSC-70510 LDH tetramer oxidises LACT to PYR IEA Sus scrofa 16651 R-SSC-71849 https://reactome.org/PathwayBrowser/#/R-SSC-71849 LDH tetramer reduces PYR to LACT IEA Sus scrofa 16651 R-SSC-8876312 https://reactome.org/PathwayBrowser/#/R-SSC-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Sus scrofa 16651 R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 16651 R-XTR-373867 https://reactome.org/PathwayBrowser/#/R-XTR-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Xenopus tropicalis 16651 R-XTR-373875 https://reactome.org/PathwayBrowser/#/R-XTR-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Xenopus tropicalis 16651 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Xenopus tropicalis 16651 R-XTR-70510 https://reactome.org/PathwayBrowser/#/R-XTR-70510 LDH tetramer oxidises LACT to PYR IEA Xenopus tropicalis 16651 R-XTR-71849 https://reactome.org/PathwayBrowser/#/R-XTR-71849 LDH tetramer reduces PYR to LACT IEA Xenopus tropicalis 16651 R-XTR-8876312 https://reactome.org/PathwayBrowser/#/R-XTR-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Xenopus tropicalis 16651 R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 166589 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 166589 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 166589 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 166589 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 166589 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 166589 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 166589 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 166589 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 166589 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 16659 R-BTA-6799495 https://reactome.org/PathwayBrowser/#/R-BTA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Bos taurus 16659 R-BTA-6813749 https://reactome.org/PathwayBrowser/#/R-BTA-6813749 ALDH1A1 oxidises GA to DGA IEA Bos taurus 16659 R-CEL-6799495 https://reactome.org/PathwayBrowser/#/R-CEL-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Caenorhabditis elegans 16659 R-CEL-6813749 https://reactome.org/PathwayBrowser/#/R-CEL-6813749 ALDH1A1 oxidises GA to DGA IEA Caenorhabditis elegans 16659 R-CFA-6799495 https://reactome.org/PathwayBrowser/#/R-CFA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Canis familiaris 16659 R-CFA-6813749 https://reactome.org/PathwayBrowser/#/R-CFA-6813749 ALDH1A1 oxidises GA to DGA IEA Canis familiaris 16659 R-DDI-6813749 https://reactome.org/PathwayBrowser/#/R-DDI-6813749 ALDH1A1 oxidises GA to DGA IEA Dictyostelium discoideum 16659 R-DME-6799495 https://reactome.org/PathwayBrowser/#/R-DME-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Drosophila melanogaster 16659 R-DME-6813749 https://reactome.org/PathwayBrowser/#/R-DME-6813749 ALDH1A1 oxidises GA to DGA IEA Drosophila melanogaster 16659 R-DRE-6799495 https://reactome.org/PathwayBrowser/#/R-DRE-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Danio rerio 16659 R-GGA-6799495 https://reactome.org/PathwayBrowser/#/R-GGA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Gallus gallus 16659 R-GGA-6813749 https://reactome.org/PathwayBrowser/#/R-GGA-6813749 ALDH1A1 oxidises GA to DGA IEA Gallus gallus 16659 R-HSA-6799495 https://reactome.org/PathwayBrowser/#/R-HSA-6799495 GLYCTK phosphorylates DGA to 3PDGA TAS Homo sapiens 16659 R-HSA-6813749 https://reactome.org/PathwayBrowser/#/R-HSA-6813749 ALDH1A1 oxidises GA to DGA TAS Homo sapiens 16659 R-MMU-6799495 https://reactome.org/PathwayBrowser/#/R-MMU-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Mus musculus 16659 R-MMU-6813749 https://reactome.org/PathwayBrowser/#/R-MMU-6813749 ALDH1A1 oxidises GA to DGA IEA Mus musculus 16659 R-RNO-6799495 https://reactome.org/PathwayBrowser/#/R-RNO-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Rattus norvegicus 16659 R-RNO-6813749 https://reactome.org/PathwayBrowser/#/R-RNO-6813749 ALDH1A1 oxidises GA to DGA IEA Rattus norvegicus 16659 R-SCE-6813749 https://reactome.org/PathwayBrowser/#/R-SCE-6813749 ALDH1A1 oxidises GA to DGA IEA Saccharomyces cerevisiae 16659 R-SPO-6813749 https://reactome.org/PathwayBrowser/#/R-SPO-6813749 ALDH1A1 oxidises GA to DGA IEA Schizosaccharomyces pombe 16659 R-SSC-6799495 https://reactome.org/PathwayBrowser/#/R-SSC-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Sus scrofa 16659 R-SSC-6813749 https://reactome.org/PathwayBrowser/#/R-SSC-6813749 ALDH1A1 oxidises GA to DGA IEA Sus scrofa 16659 R-XTR-6813749 https://reactome.org/PathwayBrowser/#/R-XTR-6813749 ALDH1A1 oxidises GA to DGA IEA Xenopus tropicalis 16670 R-BTA-1236940 https://reactome.org/PathwayBrowser/#/R-BTA-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Bos taurus 16670 R-BTA-1236941 https://reactome.org/PathwayBrowser/#/R-BTA-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Bos taurus 16670 R-BTA-1236955 https://reactome.org/PathwayBrowser/#/R-BTA-1236955 Movement of clathrin coated vesicles into early endosome IEA Bos taurus 16670 R-BTA-1236970 https://reactome.org/PathwayBrowser/#/R-BTA-1236970 Proteasomal clevage of exogenous antigen IEA Bos taurus 16670 R-BTA-168166 https://reactome.org/PathwayBrowser/#/R-BTA-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Bos taurus 16670 R-BTA-2197770 https://reactome.org/PathwayBrowser/#/R-BTA-2197770 STAB1 (FEEL-1) binds ligands IEA Bos taurus 16670 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 16670 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 16670 R-BTA-2247513 https://reactome.org/PathwayBrowser/#/R-BTA-2247513 STAB1:ligand is endocytosed IEA Bos taurus 16670 R-BTA-879411 https://reactome.org/PathwayBrowser/#/R-BTA-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Bos taurus 16670 R-BTA-8862320 https://reactome.org/PathwayBrowser/#/R-BTA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Bos taurus 16670 R-CEL-1236940 https://reactome.org/PathwayBrowser/#/R-CEL-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Caenorhabditis elegans 16670 R-CEL-1236941 https://reactome.org/PathwayBrowser/#/R-CEL-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Caenorhabditis elegans 16670 R-CEL-1236955 https://reactome.org/PathwayBrowser/#/R-CEL-1236955 Movement of clathrin coated vesicles into early endosome IEA Caenorhabditis elegans 16670 R-CEL-1236970 https://reactome.org/PathwayBrowser/#/R-CEL-1236970 Proteasomal clevage of exogenous antigen IEA Caenorhabditis elegans 16670 R-CFA-1236940 https://reactome.org/PathwayBrowser/#/R-CFA-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Canis familiaris 16670 R-CFA-1236941 https://reactome.org/PathwayBrowser/#/R-CFA-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Canis familiaris 16670 R-CFA-1236955 https://reactome.org/PathwayBrowser/#/R-CFA-1236955 Movement of clathrin coated vesicles into early endosome IEA Canis familiaris 16670 R-CFA-1236970 https://reactome.org/PathwayBrowser/#/R-CFA-1236970 Proteasomal clevage of exogenous antigen IEA Canis familiaris 16670 R-CFA-168166 https://reactome.org/PathwayBrowser/#/R-CFA-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Canis familiaris 16670 R-CFA-2197770 https://reactome.org/PathwayBrowser/#/R-CFA-2197770 STAB1 (FEEL-1) binds ligands IEA Canis familiaris 16670 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 16670 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 16670 R-CFA-2247513 https://reactome.org/PathwayBrowser/#/R-CFA-2247513 STAB1:ligand is endocytosed IEA Canis familiaris 16670 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 16670 R-CFA-879411 https://reactome.org/PathwayBrowser/#/R-CFA-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Canis familiaris 16670 R-CFA-8862320 https://reactome.org/PathwayBrowser/#/R-CFA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Canis familiaris 16670 R-DDI-1236970 https://reactome.org/PathwayBrowser/#/R-DDI-1236970 Proteasomal clevage of exogenous antigen IEA Dictyostelium discoideum 16670 R-DDI-879411 https://reactome.org/PathwayBrowser/#/R-DDI-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Dictyostelium discoideum 16670 R-DDI-8862320 https://reactome.org/PathwayBrowser/#/R-DDI-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Dictyostelium discoideum 16670 R-DME-1236940 https://reactome.org/PathwayBrowser/#/R-DME-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Drosophila melanogaster 16670 R-DME-1236941 https://reactome.org/PathwayBrowser/#/R-DME-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Drosophila melanogaster 16670 R-DME-1236955 https://reactome.org/PathwayBrowser/#/R-DME-1236955 Movement of clathrin coated vesicles into early endosome IEA Drosophila melanogaster 16670 R-DME-1236970 https://reactome.org/PathwayBrowser/#/R-DME-1236970 Proteasomal clevage of exogenous antigen IEA Drosophila melanogaster 16670 R-DME-8862320 https://reactome.org/PathwayBrowser/#/R-DME-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Drosophila melanogaster 16670 R-DRE-1236940 https://reactome.org/PathwayBrowser/#/R-DRE-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Danio rerio 16670 R-DRE-1236941 https://reactome.org/PathwayBrowser/#/R-DRE-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Danio rerio 16670 R-DRE-1236955 https://reactome.org/PathwayBrowser/#/R-DRE-1236955 Movement of clathrin coated vesicles into early endosome IEA Danio rerio 16670 R-DRE-1236970 https://reactome.org/PathwayBrowser/#/R-DRE-1236970 Proteasomal clevage of exogenous antigen IEA Danio rerio 16670 R-DRE-2197770 https://reactome.org/PathwayBrowser/#/R-DRE-2197770 STAB1 (FEEL-1) binds ligands IEA Danio rerio 16670 R-DRE-2247513 https://reactome.org/PathwayBrowser/#/R-DRE-2247513 STAB1:ligand is endocytosed IEA Danio rerio 16670 R-DRE-8862320 https://reactome.org/PathwayBrowser/#/R-DRE-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Danio rerio 16670 R-GGA-1236940 https://reactome.org/PathwayBrowser/#/R-GGA-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Gallus gallus 16670 R-GGA-1236941 https://reactome.org/PathwayBrowser/#/R-GGA-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Gallus gallus 16670 R-GGA-1236955 https://reactome.org/PathwayBrowser/#/R-GGA-1236955 Movement of clathrin coated vesicles into early endosome IEA Gallus gallus 16670 R-GGA-2197770 https://reactome.org/PathwayBrowser/#/R-GGA-2197770 STAB1 (FEEL-1) binds ligands IEA Gallus gallus 16670 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 16670 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 16670 R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus 16670 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 16670 R-GGA-8862320 https://reactome.org/PathwayBrowser/#/R-GGA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Gallus gallus 16670 R-HSA-1236939 https://reactome.org/PathwayBrowser/#/R-HSA-1236939 Interaction of exogenous soluble antigen with its corresponding receptor IEA Homo sapiens 16670 R-HSA-1236940 https://reactome.org/PathwayBrowser/#/R-HSA-1236940 Exogenous soluble antigen targeted to more stable early endosome TAS Homo sapiens 16670 R-HSA-1236941 https://reactome.org/PathwayBrowser/#/R-HSA-1236941 Internalization of receptor bound antigen into clathrin coted vesicles TAS Homo sapiens 16670 R-HSA-1236948 https://reactome.org/PathwayBrowser/#/R-HSA-1236948 Antigen processing by cathepsin S in endosoytic vesicle IEA Homo sapiens 16670 R-HSA-1236955 https://reactome.org/PathwayBrowser/#/R-HSA-1236955 Movement of clathrin coated vesicles into early endosome TAS Homo sapiens 16670 R-HSA-1236968 https://reactome.org/PathwayBrowser/#/R-HSA-1236968 Egress of internalized antigen into cytosol from early endosome TAS Homo sapiens 16670 R-HSA-1236970 https://reactome.org/PathwayBrowser/#/R-HSA-1236970 Proteasomal clevage of exogenous antigen TAS Homo sapiens 16670 R-HSA-168166 https://reactome.org/PathwayBrowser/#/R-HSA-168166 NF-kappa-B complex is transported from cytosol to nucleus TAS Homo sapiens 16670 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 16670 R-HSA-2197770 https://reactome.org/PathwayBrowser/#/R-HSA-2197770 STAB1 (FEEL-1) binds ligands TAS Homo sapiens 16670 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 16670 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 16670 R-HSA-2247513 https://reactome.org/PathwayBrowser/#/R-HSA-2247513 STAB1:ligand is endocytosed TAS Homo sapiens 16670 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 16670 R-HSA-6789109 https://reactome.org/PathwayBrowser/#/R-HSA-6789109 Superoxide anion reacts with Fe-S cluster TAS Homo sapiens 16670 R-HSA-6789208 https://reactome.org/PathwayBrowser/#/R-HSA-6789208 HOCl-induced glycosaminoglycan fragmentation TAS Homo sapiens 16670 R-HSA-879358 https://reactome.org/PathwayBrowser/#/R-HSA-879358 AGER-1,2,3 bind AGEs IEA Homo sapiens 16670 R-HSA-879362 https://reactome.org/PathwayBrowser/#/R-HSA-879362 AGER binds ERK1/2 IEA Homo sapiens 16670 R-HSA-879411 https://reactome.org/PathwayBrowser/#/R-HSA-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor TAS Homo sapiens 16670 R-HSA-8862320 https://reactome.org/PathwayBrowser/#/R-HSA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall TAS Homo sapiens 16670 R-MMU-1236940 https://reactome.org/PathwayBrowser/#/R-MMU-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Mus musculus 16670 R-MMU-1236941 https://reactome.org/PathwayBrowser/#/R-MMU-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Mus musculus 16670 R-MMU-1236955 https://reactome.org/PathwayBrowser/#/R-MMU-1236955 Movement of clathrin coated vesicles into early endosome IEA Mus musculus 16670 R-MMU-1236970 https://reactome.org/PathwayBrowser/#/R-MMU-1236970 Proteasomal clevage of exogenous antigen IEA Mus musculus 16670 R-MMU-168166 https://reactome.org/PathwayBrowser/#/R-MMU-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Mus musculus 16670 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 16670 R-MMU-2197770 https://reactome.org/PathwayBrowser/#/R-MMU-2197770 STAB1 (FEEL-1) binds ligands IEA Mus musculus 16670 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 16670 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 16670 R-MMU-2247513 https://reactome.org/PathwayBrowser/#/R-MMU-2247513 STAB1:ligand is endocytosed IEA Mus musculus 16670 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 16670 R-MMU-879411 https://reactome.org/PathwayBrowser/#/R-MMU-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Mus musculus 16670 R-MMU-8862320 https://reactome.org/PathwayBrowser/#/R-MMU-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Mus musculus 16670 R-NUL-997411 https://reactome.org/PathwayBrowser/#/R-NUL-997411 AGER binds rat ERK1/2 TAS Homo sapiens 16670 R-PFA-1236970 https://reactome.org/PathwayBrowser/#/R-PFA-1236970 Proteasomal clevage of exogenous antigen IEA Plasmodium falciparum 16670 R-RNO-1236940 https://reactome.org/PathwayBrowser/#/R-RNO-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Rattus norvegicus 16670 R-RNO-1236941 https://reactome.org/PathwayBrowser/#/R-RNO-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Rattus norvegicus 16670 R-RNO-1236955 https://reactome.org/PathwayBrowser/#/R-RNO-1236955 Movement of clathrin coated vesicles into early endosome IEA Rattus norvegicus 16670 R-RNO-1236970 https://reactome.org/PathwayBrowser/#/R-RNO-1236970 Proteasomal clevage of exogenous antigen IEA Rattus norvegicus 16670 R-RNO-168166 https://reactome.org/PathwayBrowser/#/R-RNO-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Rattus norvegicus 16670 R-RNO-2197770 https://reactome.org/PathwayBrowser/#/R-RNO-2197770 STAB1 (FEEL-1) binds ligands IEA Rattus norvegicus 16670 R-RNO-2247513 https://reactome.org/PathwayBrowser/#/R-RNO-2247513 STAB1:ligand is endocytosed IEA Rattus norvegicus 16670 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 16670 R-RNO-879411 https://reactome.org/PathwayBrowser/#/R-RNO-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Rattus norvegicus 16670 R-RNO-8862320 https://reactome.org/PathwayBrowser/#/R-RNO-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Rattus norvegicus 16670 R-SCE-1236970 https://reactome.org/PathwayBrowser/#/R-SCE-1236970 Proteasomal clevage of exogenous antigen IEA Saccharomyces cerevisiae 16670 R-SPO-1236970 https://reactome.org/PathwayBrowser/#/R-SPO-1236970 Proteasomal clevage of exogenous antigen IEA Schizosaccharomyces pombe 16670 R-SSC-1236940 https://reactome.org/PathwayBrowser/#/R-SSC-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Sus scrofa 16670 R-SSC-1236941 https://reactome.org/PathwayBrowser/#/R-SSC-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Sus scrofa 16670 R-SSC-1236955 https://reactome.org/PathwayBrowser/#/R-SSC-1236955 Movement of clathrin coated vesicles into early endosome IEA Sus scrofa 16670 R-SSC-1236970 https://reactome.org/PathwayBrowser/#/R-SSC-1236970 Proteasomal clevage of exogenous antigen IEA Sus scrofa 16670 R-SSC-168166 https://reactome.org/PathwayBrowser/#/R-SSC-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Sus scrofa 16670 R-SSC-2197770 https://reactome.org/PathwayBrowser/#/R-SSC-2197770 STAB1 (FEEL-1) binds ligands IEA Sus scrofa 16670 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 16670 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 16670 R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa 16670 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 16670 R-SSC-879411 https://reactome.org/PathwayBrowser/#/R-SSC-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Sus scrofa 16670 R-SSC-8862320 https://reactome.org/PathwayBrowser/#/R-SSC-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Sus scrofa 16670 R-XTR-1236940 https://reactome.org/PathwayBrowser/#/R-XTR-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Xenopus tropicalis 16670 R-XTR-1236941 https://reactome.org/PathwayBrowser/#/R-XTR-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Xenopus tropicalis 16670 R-XTR-1236955 https://reactome.org/PathwayBrowser/#/R-XTR-1236955 Movement of clathrin coated vesicles into early endosome IEA Xenopus tropicalis 16670 R-XTR-879411 https://reactome.org/PathwayBrowser/#/R-XTR-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Xenopus tropicalis 16670 R-XTR-8862320 https://reactome.org/PathwayBrowser/#/R-XTR-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Xenopus tropicalis 166776 R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 166776 R-BTA-9758682 https://reactome.org/PathwayBrowser/#/R-BTA-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Bos taurus 166776 R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 166776 R-CEL-9758682 https://reactome.org/PathwayBrowser/#/R-CEL-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Caenorhabditis elegans 166776 R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 166776 R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 166776 R-DDI-9758682 https://reactome.org/PathwayBrowser/#/R-DDI-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Dictyostelium discoideum 166776 R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 166776 R-DME-9758682 https://reactome.org/PathwayBrowser/#/R-DME-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Drosophila melanogaster 166776 R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 166776 R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 166776 R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 166776 R-HSA-9758682 https://reactome.org/PathwayBrowser/#/R-HSA-9758682 AKR1C1 hydrogenates PREDN,PREDL TAS Homo sapiens 166776 R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 166776 R-MMU-9758682 https://reactome.org/PathwayBrowser/#/R-MMU-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Mus musculus 166776 R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 166776 R-RNO-9758682 https://reactome.org/PathwayBrowser/#/R-RNO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Rattus norvegicus 166776 R-SCE-9758682 https://reactome.org/PathwayBrowser/#/R-SCE-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Saccharomyces cerevisiae 166776 R-SPO-9758682 https://reactome.org/PathwayBrowser/#/R-SPO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Schizosaccharomyces pombe 166776 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 166776 R-SSC-9758682 https://reactome.org/PathwayBrowser/#/R-SSC-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Sus scrofa 166776 R-XTR-9758682 https://reactome.org/PathwayBrowser/#/R-XTR-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Xenopus tropicalis 16704 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 16704 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 16704 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 16704 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 16704 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 16704 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16704 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16704 R-BTA-109530 https://reactome.org/PathwayBrowser/#/R-BTA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Bos taurus 16704 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 16704 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 16704 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 16704 R-BTA-109539 https://reactome.org/PathwayBrowser/#/R-BTA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Bos taurus 16704 R-BTA-109903 https://reactome.org/PathwayBrowser/#/R-BTA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Bos taurus 16704 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 16704 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 16704 R-BTA-73599 https://reactome.org/PathwayBrowser/#/R-BTA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Bos taurus 16704 R-BTA-73608 https://reactome.org/PathwayBrowser/#/R-BTA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Bos taurus 16704 R-BTA-74372 https://reactome.org/PathwayBrowser/#/R-BTA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Bos taurus 16704 R-BTA-74376 https://reactome.org/PathwayBrowser/#/R-BTA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Bos taurus 16704 R-BTA-8954327 https://reactome.org/PathwayBrowser/#/R-BTA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Bos taurus 16704 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 16704 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16704 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16704 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans 16704 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 16704 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 16704 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 16704 R-CEL-109539 https://reactome.org/PathwayBrowser/#/R-CEL-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Caenorhabditis elegans 16704 R-CEL-109903 https://reactome.org/PathwayBrowser/#/R-CEL-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Caenorhabditis elegans 16704 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 16704 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 16704 R-CEL-73599 https://reactome.org/PathwayBrowser/#/R-CEL-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Caenorhabditis elegans 16704 R-CEL-73608 https://reactome.org/PathwayBrowser/#/R-CEL-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Caenorhabditis elegans 16704 R-CEL-74372 https://reactome.org/PathwayBrowser/#/R-CEL-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Caenorhabditis elegans 16704 R-CEL-74376 https://reactome.org/PathwayBrowser/#/R-CEL-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Caenorhabditis elegans 16704 R-CEL-8954327 https://reactome.org/PathwayBrowser/#/R-CEL-8954327 UCKL1 phosphorylates urindine, cytidine IEA Caenorhabditis elegans 16704 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 16704 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 16704 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 16704 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 16704 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 16704 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16704 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16704 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 16704 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 16704 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 16704 R-CFA-109903 https://reactome.org/PathwayBrowser/#/R-CFA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Canis familiaris 16704 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 16704 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 16704 R-CFA-73599 https://reactome.org/PathwayBrowser/#/R-CFA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Canis familiaris 16704 R-CFA-73608 https://reactome.org/PathwayBrowser/#/R-CFA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Canis familiaris 16704 R-CFA-74372 https://reactome.org/PathwayBrowser/#/R-CFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Canis familiaris 16704 R-CFA-74376 https://reactome.org/PathwayBrowser/#/R-CFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Canis familiaris 16704 R-CFA-8954327 https://reactome.org/PathwayBrowser/#/R-CFA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Canis familiaris 16704 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16704 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16704 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 16704 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 16704 R-DDI-109903 https://reactome.org/PathwayBrowser/#/R-DDI-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Dictyostelium discoideum 16704 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 16704 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 16704 R-DDI-73599 https://reactome.org/PathwayBrowser/#/R-DDI-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Dictyostelium discoideum 16704 R-DDI-73608 https://reactome.org/PathwayBrowser/#/R-DDI-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Dictyostelium discoideum 16704 R-DDI-74372 https://reactome.org/PathwayBrowser/#/R-DDI-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Dictyostelium discoideum 16704 R-DDI-74376 https://reactome.org/PathwayBrowser/#/R-DDI-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Dictyostelium discoideum 16704 R-DDI-8954327 https://reactome.org/PathwayBrowser/#/R-DDI-8954327 UCKL1 phosphorylates urindine, cytidine IEA Dictyostelium discoideum 16704 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 16704 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 16704 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16704 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16704 R-DME-109530 https://reactome.org/PathwayBrowser/#/R-DME-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Drosophila melanogaster 16704 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 16704 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 16704 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 16704 R-DME-109539 https://reactome.org/PathwayBrowser/#/R-DME-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Drosophila melanogaster 16704 R-DME-109903 https://reactome.org/PathwayBrowser/#/R-DME-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Drosophila melanogaster 16704 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 16704 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 16704 R-DME-73599 https://reactome.org/PathwayBrowser/#/R-DME-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Drosophila melanogaster 16704 R-DME-73608 https://reactome.org/PathwayBrowser/#/R-DME-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Drosophila melanogaster 16704 R-DME-74372 https://reactome.org/PathwayBrowser/#/R-DME-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Drosophila melanogaster 16704 R-DME-74376 https://reactome.org/PathwayBrowser/#/R-DME-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Drosophila melanogaster 16704 R-DME-8954327 https://reactome.org/PathwayBrowser/#/R-DME-8954327 UCKL1 phosphorylates urindine, cytidine IEA Drosophila melanogaster 16704 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 16704 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 16704 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 16704 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 16704 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 16704 R-DRE-109903 https://reactome.org/PathwayBrowser/#/R-DRE-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Danio rerio 16704 R-DRE-73599 https://reactome.org/PathwayBrowser/#/R-DRE-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Danio rerio 16704 R-DRE-73608 https://reactome.org/PathwayBrowser/#/R-DRE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Danio rerio 16704 R-DRE-74372 https://reactome.org/PathwayBrowser/#/R-DRE-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Danio rerio 16704 R-DRE-74376 https://reactome.org/PathwayBrowser/#/R-DRE-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Danio rerio 16704 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 16704 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 16704 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 16704 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 16704 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 16704 R-GGA-109539 https://reactome.org/PathwayBrowser/#/R-GGA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Gallus gallus 16704 R-GGA-109903 https://reactome.org/PathwayBrowser/#/R-GGA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Gallus gallus 16704 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 16704 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 16704 R-GGA-73599 https://reactome.org/PathwayBrowser/#/R-GGA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Gallus gallus 16704 R-GGA-73608 https://reactome.org/PathwayBrowser/#/R-GGA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Gallus gallus 16704 R-GGA-74372 https://reactome.org/PathwayBrowser/#/R-GGA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Gallus gallus 16704 R-GGA-74376 https://reactome.org/PathwayBrowser/#/R-GGA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Gallus gallus 16704 R-GGA-8954327 https://reactome.org/PathwayBrowser/#/R-GGA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Gallus gallus 16704 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 16704 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 16704 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 16704 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 16704 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 16704 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16704 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16704 R-HSA-109530 https://reactome.org/PathwayBrowser/#/R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 TAS Homo sapiens 16704 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 16704 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 16704 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 16704 R-HSA-109539 https://reactome.org/PathwayBrowser/#/R-HSA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 TAS Homo sapiens 16704 R-HSA-109903 https://reactome.org/PathwayBrowser/#/R-HSA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] TAS Homo sapiens 16704 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 16704 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 16704 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 16704 R-HSA-73599 https://reactome.org/PathwayBrowser/#/R-HSA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] TAS Homo sapiens 16704 R-HSA-73608 https://reactome.org/PathwayBrowser/#/R-HSA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) TAS Homo sapiens 16704 R-HSA-74372 https://reactome.org/PathwayBrowser/#/R-HSA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] TAS Homo sapiens 16704 R-HSA-74376 https://reactome.org/PathwayBrowser/#/R-HSA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) TAS Homo sapiens 16704 R-HSA-8954327 https://reactome.org/PathwayBrowser/#/R-HSA-8954327 UCKL1 phosphorylates urindine, cytidine TAS Homo sapiens 16704 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 16704 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 16704 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 16704 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 16704 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 16704 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16704 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16704 R-MMU-109530 https://reactome.org/PathwayBrowser/#/R-MMU-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Mus musculus 16704 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 16704 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 16704 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 16704 R-MMU-109539 https://reactome.org/PathwayBrowser/#/R-MMU-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Mus musculus 16704 R-MMU-109903 https://reactome.org/PathwayBrowser/#/R-MMU-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Mus musculus 16704 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 16704 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 16704 R-MMU-73599 https://reactome.org/PathwayBrowser/#/R-MMU-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Mus musculus 16704 R-MMU-73608 https://reactome.org/PathwayBrowser/#/R-MMU-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Mus musculus 16704 R-MMU-74372 https://reactome.org/PathwayBrowser/#/R-MMU-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Mus musculus 16704 R-MMU-74376 https://reactome.org/PathwayBrowser/#/R-MMU-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Mus musculus 16704 R-MMU-8954327 https://reactome.org/PathwayBrowser/#/R-MMU-8954327 UCKL1 phosphorylates urindine, cytidine IEA Mus musculus 16704 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16704 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16704 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 16704 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 16704 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 16704 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 16704 R-PFA-74372 https://reactome.org/PathwayBrowser/#/R-PFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Plasmodium falciparum 16704 R-PFA-74376 https://reactome.org/PathwayBrowser/#/R-PFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Plasmodium falciparum 16704 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 16704 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 16704 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 16704 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 16704 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 16704 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16704 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16704 R-RNO-109530 https://reactome.org/PathwayBrowser/#/R-RNO-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Rattus norvegicus 16704 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 16704 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 16704 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 16704 R-RNO-109539 https://reactome.org/PathwayBrowser/#/R-RNO-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Rattus norvegicus 16704 R-RNO-109903 https://reactome.org/PathwayBrowser/#/R-RNO-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Rattus norvegicus 16704 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 16704 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 16704 R-RNO-73599 https://reactome.org/PathwayBrowser/#/R-RNO-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Rattus norvegicus 16704 R-RNO-73608 https://reactome.org/PathwayBrowser/#/R-RNO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Rattus norvegicus 16704 R-RNO-74372 https://reactome.org/PathwayBrowser/#/R-RNO-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Rattus norvegicus 16704 R-RNO-74376 https://reactome.org/PathwayBrowser/#/R-RNO-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Rattus norvegicus 16704 R-RNO-8954327 https://reactome.org/PathwayBrowser/#/R-RNO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Rattus norvegicus 16704 R-SCE-73608 https://reactome.org/PathwayBrowser/#/R-SCE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Saccharomyces cerevisiae 16704 R-SCE-8954327 https://reactome.org/PathwayBrowser/#/R-SCE-8954327 UCKL1 phosphorylates urindine, cytidine IEA Saccharomyces cerevisiae 16704 R-SPO-73608 https://reactome.org/PathwayBrowser/#/R-SPO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Schizosaccharomyces pombe 16704 R-SPO-8954327 https://reactome.org/PathwayBrowser/#/R-SPO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Schizosaccharomyces pombe 16704 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 16704 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 16704 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 16704 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 16704 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 16704 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16704 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16704 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa 16704 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 16704 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 16704 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 16704 R-SSC-109539 https://reactome.org/PathwayBrowser/#/R-SSC-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Sus scrofa 16704 R-SSC-109903 https://reactome.org/PathwayBrowser/#/R-SSC-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Sus scrofa 16704 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 16704 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 16704 R-SSC-73599 https://reactome.org/PathwayBrowser/#/R-SSC-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Sus scrofa 16704 R-SSC-73608 https://reactome.org/PathwayBrowser/#/R-SSC-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Sus scrofa 16704 R-SSC-74372 https://reactome.org/PathwayBrowser/#/R-SSC-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Sus scrofa 16704 R-SSC-74376 https://reactome.org/PathwayBrowser/#/R-SSC-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Sus scrofa 16704 R-SSC-8954327 https://reactome.org/PathwayBrowser/#/R-SSC-8954327 UCKL1 phosphorylates urindine, cytidine IEA Sus scrofa 16704 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 16704 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 16704 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 16704 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 16704 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 16704 R-XTR-109530 https://reactome.org/PathwayBrowser/#/R-XTR-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Xenopus tropicalis 16704 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 16704 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 16704 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 16704 R-XTR-109539 https://reactome.org/PathwayBrowser/#/R-XTR-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Xenopus tropicalis 16704 R-XTR-109903 https://reactome.org/PathwayBrowser/#/R-XTR-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Xenopus tropicalis 16704 R-XTR-73599 https://reactome.org/PathwayBrowser/#/R-XTR-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Xenopus tropicalis 16704 R-XTR-73608 https://reactome.org/PathwayBrowser/#/R-XTR-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Xenopus tropicalis 16704 R-XTR-74372 https://reactome.org/PathwayBrowser/#/R-XTR-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Xenopus tropicalis 16704 R-XTR-74376 https://reactome.org/PathwayBrowser/#/R-XTR-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Xenopus tropicalis 16704 R-XTR-8954327 https://reactome.org/PathwayBrowser/#/R-XTR-8954327 UCKL1 phosphorylates urindine, cytidine IEA Xenopus tropicalis 16708 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16708 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16708 R-BTA-110246 https://reactome.org/PathwayBrowser/#/R-BTA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Bos taurus 16708 R-BTA-1237160 https://reactome.org/PathwayBrowser/#/R-BTA-1237160 MTA is cleaved and phosphorylated IEA Bos taurus 16708 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 16708 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 16708 R-BTA-74213 https://reactome.org/PathwayBrowser/#/R-BTA-74213 APRT catalyzes the conversion of adenine to AMP IEA Bos taurus 16708 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16708 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16708 R-CEL-1237160 https://reactome.org/PathwayBrowser/#/R-CEL-1237160 MTA is cleaved and phosphorylated IEA Caenorhabditis elegans 16708 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 16708 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 16708 R-CEL-74213 https://reactome.org/PathwayBrowser/#/R-CEL-74213 APRT catalyzes the conversion of adenine to AMP IEA Caenorhabditis elegans 16708 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16708 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16708 R-CFA-110246 https://reactome.org/PathwayBrowser/#/R-CFA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Canis familiaris 16708 R-CFA-1237160 https://reactome.org/PathwayBrowser/#/R-CFA-1237160 MTA is cleaved and phosphorylated IEA Canis familiaris 16708 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 16708 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 16708 R-CFA-74213 https://reactome.org/PathwayBrowser/#/R-CFA-74213 APRT catalyzes the conversion of adenine to AMP IEA Canis familiaris 16708 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16708 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16708 R-DDI-110246 https://reactome.org/PathwayBrowser/#/R-DDI-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Dictyostelium discoideum 16708 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 16708 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 16708 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16708 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16708 R-DME-1237160 https://reactome.org/PathwayBrowser/#/R-DME-1237160 MTA is cleaved and phosphorylated IEA Drosophila melanogaster 16708 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 16708 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 16708 R-DME-74213 https://reactome.org/PathwayBrowser/#/R-DME-74213 APRT catalyzes the conversion of adenine to AMP IEA Drosophila melanogaster 16708 R-DRE-1237160 https://reactome.org/PathwayBrowser/#/R-DRE-1237160 MTA is cleaved and phosphorylated IEA Danio rerio 16708 R-DRE-74213 https://reactome.org/PathwayBrowser/#/R-DRE-74213 APRT catalyzes the conversion of adenine to AMP IEA Danio rerio 16708 R-GGA-110246 https://reactome.org/PathwayBrowser/#/R-GGA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Gallus gallus 16708 R-GGA-1237160 https://reactome.org/PathwayBrowser/#/R-GGA-1237160 MTA is cleaved and phosphorylated IEA Gallus gallus 16708 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 16708 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 16708 R-GGA-74213 https://reactome.org/PathwayBrowser/#/R-GGA-74213 APRT catalyzes the conversion of adenine to AMP IEA Gallus gallus 16708 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16708 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16708 R-HSA-110246 https://reactome.org/PathwayBrowser/#/R-HSA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH TAS Homo sapiens 16708 R-HSA-1237160 https://reactome.org/PathwayBrowser/#/R-HSA-1237160 MTA is cleaved and phosphorylated TAS Homo sapiens 16708 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 16708 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 16708 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 16708 R-HSA-74213 https://reactome.org/PathwayBrowser/#/R-HSA-74213 APRT catalyzes the conversion of adenine to AMP TAS Homo sapiens 16708 R-HSA-9734193 https://reactome.org/PathwayBrowser/#/R-HSA-9734193 Defective APRT does not convert adenine to AMP TAS Homo sapiens 16708 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16708 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16708 R-MMU-110246 https://reactome.org/PathwayBrowser/#/R-MMU-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Mus musculus 16708 R-MMU-1237160 https://reactome.org/PathwayBrowser/#/R-MMU-1237160 MTA is cleaved and phosphorylated IEA Mus musculus 16708 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 16708 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 16708 R-MMU-74213 https://reactome.org/PathwayBrowser/#/R-MMU-74213 APRT catalyzes the conversion of adenine to AMP IEA Mus musculus 16708 R-NUL-9635966 https://reactome.org/PathwayBrowser/#/R-NUL-9635966 Mutyh cleaves adenine mispaired with 8-oxoguanine TAS Mus musculus 16708 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16708 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16708 R-PFA-110246 https://reactome.org/PathwayBrowser/#/R-PFA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Plasmodium falciparum 16708 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 16708 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 16708 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16708 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16708 R-RNO-110246 https://reactome.org/PathwayBrowser/#/R-RNO-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Rattus norvegicus 16708 R-RNO-1237160 https://reactome.org/PathwayBrowser/#/R-RNO-1237160 MTA is cleaved and phosphorylated IEA Rattus norvegicus 16708 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 16708 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 16708 R-RNO-74213 https://reactome.org/PathwayBrowser/#/R-RNO-74213 APRT catalyzes the conversion of adenine to AMP IEA Rattus norvegicus 16708 R-SCE-1237160 https://reactome.org/PathwayBrowser/#/R-SCE-1237160 MTA is cleaved and phosphorylated IEA Saccharomyces cerevisiae 16708 R-SCE-74213 https://reactome.org/PathwayBrowser/#/R-SCE-74213 APRT catalyzes the conversion of adenine to AMP IEA Saccharomyces cerevisiae 16708 R-SPO-110246 https://reactome.org/PathwayBrowser/#/R-SPO-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Schizosaccharomyces pombe 16708 R-SPO-1237160 https://reactome.org/PathwayBrowser/#/R-SPO-1237160 MTA is cleaved and phosphorylated IEA Schizosaccharomyces pombe 16708 R-SPO-74213 https://reactome.org/PathwayBrowser/#/R-SPO-74213 APRT catalyzes the conversion of adenine to AMP IEA Schizosaccharomyces pombe 16708 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16708 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16708 R-SSC-110246 https://reactome.org/PathwayBrowser/#/R-SSC-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Sus scrofa 16708 R-SSC-1237160 https://reactome.org/PathwayBrowser/#/R-SSC-1237160 MTA is cleaved and phosphorylated IEA Sus scrofa 16708 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 16708 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 16708 R-SSC-74213 https://reactome.org/PathwayBrowser/#/R-SSC-74213 APRT catalyzes the conversion of adenine to AMP IEA Sus scrofa 16708 R-XTR-110246 https://reactome.org/PathwayBrowser/#/R-XTR-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Xenopus tropicalis 16708 R-XTR-1237160 https://reactome.org/PathwayBrowser/#/R-XTR-1237160 MTA is cleaved and phosphorylated IEA Xenopus tropicalis 16708 R-XTR-74213 https://reactome.org/PathwayBrowser/#/R-XTR-74213 APRT catalyzes the conversion of adenine to AMP IEA Xenopus tropicalis 16709 R-BTA-964962 https://reactome.org/PathwayBrowser/#/R-BTA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Bos taurus 16709 R-CEL-964962 https://reactome.org/PathwayBrowser/#/R-CEL-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Caenorhabditis elegans 16709 R-CFA-964962 https://reactome.org/PathwayBrowser/#/R-CFA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Canis familiaris 16709 R-DDI-964962 https://reactome.org/PathwayBrowser/#/R-DDI-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Dictyostelium discoideum 16709 R-DME-964962 https://reactome.org/PathwayBrowser/#/R-DME-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Drosophila melanogaster 16709 R-DRE-964962 https://reactome.org/PathwayBrowser/#/R-DRE-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Danio rerio 16709 R-GGA-964962 https://reactome.org/PathwayBrowser/#/R-GGA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Gallus gallus 16709 R-HSA-964962 https://reactome.org/PathwayBrowser/#/R-HSA-964962 2xPDKX:2xZn2+ phosphorylates PDX TAS Homo sapiens 16709 R-MMU-964962 https://reactome.org/PathwayBrowser/#/R-MMU-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Mus musculus 16709 R-PFA-964962 https://reactome.org/PathwayBrowser/#/R-PFA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Plasmodium falciparum 16709 R-RNO-964962 https://reactome.org/PathwayBrowser/#/R-RNO-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Rattus norvegicus 16709 R-SCE-964962 https://reactome.org/PathwayBrowser/#/R-SCE-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Saccharomyces cerevisiae 16709 R-SPO-964962 https://reactome.org/PathwayBrowser/#/R-SPO-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Schizosaccharomyces pombe 16709 R-SSC-964962 https://reactome.org/PathwayBrowser/#/R-SSC-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Sus scrofa 16709 R-XTR-964962 https://reactome.org/PathwayBrowser/#/R-XTR-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Xenopus tropicalis 16716 R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 16716 R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 16716 R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 16716 R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 16716 R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 16716 R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 16716 R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 16716 R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 16716 R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 16716 R-RNO-76416 https://reactome.org/PathwayBrowser/#/R-RNO-76416 Benzene is hydroxylated to phenol IEA Rattus norvegicus 16716 R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa 16716 R-XTR-76416 https://reactome.org/PathwayBrowser/#/R-XTR-76416 Benzene is hydroxylated to phenol IEA Xenopus tropicalis 16723 R-BTA-1237119 https://reactome.org/PathwayBrowser/#/R-BTA-1237119 Acireductone is oxidized to MOB IEA Bos taurus 16723 R-CEL-1237119 https://reactome.org/PathwayBrowser/#/R-CEL-1237119 Acireductone is oxidized to MOB IEA Caenorhabditis elegans 16723 R-CFA-1237119 https://reactome.org/PathwayBrowser/#/R-CFA-1237119 Acireductone is oxidized to MOB IEA Canis familiaris 16723 R-CFS-1237106 https://reactome.org/PathwayBrowser/#/R-CFS-1237106 Transamination of MOB to methionine TAS Crithidia fasciculata 16723 R-DDI-1237119 https://reactome.org/PathwayBrowser/#/R-DDI-1237119 Acireductone is oxidized to MOB IEA Dictyostelium discoideum 16723 R-DME-1237119 https://reactome.org/PathwayBrowser/#/R-DME-1237119 Acireductone is oxidized to MOB IEA Drosophila melanogaster 16723 R-DRE-1237119 https://reactome.org/PathwayBrowser/#/R-DRE-1237119 Acireductone is oxidized to MOB IEA Danio rerio 16723 R-GGA-1237119 https://reactome.org/PathwayBrowser/#/R-GGA-1237119 Acireductone is oxidized to MOB IEA Gallus gallus 16723 R-HSA-1237102 https://reactome.org/PathwayBrowser/#/R-HSA-1237102 Transamination of MOB to methionine IEA Homo sapiens 16723 R-HSA-1237119 https://reactome.org/PathwayBrowser/#/R-HSA-1237119 Acireductone is oxidized to MOB TAS Homo sapiens 16723 R-MMU-1237119 https://reactome.org/PathwayBrowser/#/R-MMU-1237119 Acireductone is oxidized to MOB IEA Mus musculus 16723 R-RNO-1237119 https://reactome.org/PathwayBrowser/#/R-RNO-1237119 Acireductone is oxidized to MOB IEA Rattus norvegicus 16723 R-SCE-1237119 https://reactome.org/PathwayBrowser/#/R-SCE-1237119 Acireductone is oxidized to MOB IEA Saccharomyces cerevisiae 16723 R-SPO-1237119 https://reactome.org/PathwayBrowser/#/R-SPO-1237119 Acireductone is oxidized to MOB IEA Schizosaccharomyces pombe 16723 R-SSC-1237119 https://reactome.org/PathwayBrowser/#/R-SSC-1237119 Acireductone is oxidized to MOB IEA Sus scrofa 16723 R-XTR-1237119 https://reactome.org/PathwayBrowser/#/R-XTR-1237119 Acireductone is oxidized to MOB IEA Xenopus tropicalis 16724 R-BTA-70994 https://reactome.org/PathwayBrowser/#/R-BTA-70994 SDH complex dehydrogenates succinate IEA Bos taurus 16724 R-BTA-880002 https://reactome.org/PathwayBrowser/#/R-BTA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Bos taurus 16724 R-BTA-880033 https://reactome.org/PathwayBrowser/#/R-BTA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Bos taurus 16724 R-BTA-9855252 https://reactome.org/PathwayBrowser/#/R-BTA-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Bos taurus 16724 R-CEL-70994 https://reactome.org/PathwayBrowser/#/R-CEL-70994 SDH complex dehydrogenates succinate IEA Caenorhabditis elegans 16724 R-CEL-880002 https://reactome.org/PathwayBrowser/#/R-CEL-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Caenorhabditis elegans 16724 R-CEL-880033 https://reactome.org/PathwayBrowser/#/R-CEL-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Caenorhabditis elegans 16724 R-CFA-70994 https://reactome.org/PathwayBrowser/#/R-CFA-70994 SDH complex dehydrogenates succinate IEA Canis familiaris 16724 R-CFA-880002 https://reactome.org/PathwayBrowser/#/R-CFA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Canis familiaris 16724 R-CFA-880033 https://reactome.org/PathwayBrowser/#/R-CFA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Canis familiaris 16724 R-DDI-70994 https://reactome.org/PathwayBrowser/#/R-DDI-70994 SDH complex dehydrogenates succinate IEA Dictyostelium discoideum 16724 R-DDI-880002 https://reactome.org/PathwayBrowser/#/R-DDI-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Dictyostelium discoideum 16724 R-DDI-880033 https://reactome.org/PathwayBrowser/#/R-DDI-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Dictyostelium discoideum 16724 R-DME-70994 https://reactome.org/PathwayBrowser/#/R-DME-70994 SDH complex dehydrogenates succinate IEA Drosophila melanogaster 16724 R-DME-880002 https://reactome.org/PathwayBrowser/#/R-DME-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Drosophila melanogaster 16724 R-DME-880033 https://reactome.org/PathwayBrowser/#/R-DME-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Drosophila melanogaster 16724 R-DRE-70994 https://reactome.org/PathwayBrowser/#/R-DRE-70994 SDH complex dehydrogenates succinate IEA Danio rerio 16724 R-DRE-880002 https://reactome.org/PathwayBrowser/#/R-DRE-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Danio rerio 16724 R-DRE-880033 https://reactome.org/PathwayBrowser/#/R-DRE-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Danio rerio 16724 R-GGA-70994 https://reactome.org/PathwayBrowser/#/R-GGA-70994 SDH complex dehydrogenates succinate IEA Gallus gallus 16724 R-GGA-880002 https://reactome.org/PathwayBrowser/#/R-GGA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Gallus gallus 16724 R-GGA-880033 https://reactome.org/PathwayBrowser/#/R-GGA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Gallus gallus 16724 R-HSA-163213 https://reactome.org/PathwayBrowser/#/R-HSA-163213 Transfer of electrons through the succinate dehydrogenase complex IEA Homo sapiens 16724 R-HSA-70994 https://reactome.org/PathwayBrowser/#/R-HSA-70994 SDH complex dehydrogenates succinate TAS Homo sapiens 16724 R-HSA-880002 https://reactome.org/PathwayBrowser/#/R-HSA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate TAS Homo sapiens 16724 R-HSA-880033 https://reactome.org/PathwayBrowser/#/R-HSA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde TAS Homo sapiens 16724 R-HSA-9855252 https://reactome.org/PathwayBrowser/#/R-HSA-9855252 SDHA:SDHB binds to SDHC:SDHD TAS Homo sapiens 16724 R-MMU-70994 https://reactome.org/PathwayBrowser/#/R-MMU-70994 SDH complex dehydrogenates succinate IEA Mus musculus 16724 R-MMU-880002 https://reactome.org/PathwayBrowser/#/R-MMU-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Mus musculus 16724 R-MMU-880033 https://reactome.org/PathwayBrowser/#/R-MMU-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Mus musculus 16724 R-MMU-9855252 https://reactome.org/PathwayBrowser/#/R-MMU-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Mus musculus 16724 R-RNO-70994 https://reactome.org/PathwayBrowser/#/R-RNO-70994 SDH complex dehydrogenates succinate IEA Rattus norvegicus 16724 R-RNO-880002 https://reactome.org/PathwayBrowser/#/R-RNO-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Rattus norvegicus 16724 R-RNO-880033 https://reactome.org/PathwayBrowser/#/R-RNO-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Rattus norvegicus 16724 R-SCE-70994 https://reactome.org/PathwayBrowser/#/R-SCE-70994 SDH complex dehydrogenates succinate IEA Saccharomyces cerevisiae 16724 R-SPO-70994 https://reactome.org/PathwayBrowser/#/R-SPO-70994 SDH complex dehydrogenates succinate IEA Schizosaccharomyces pombe 16724 R-SSC-70994 https://reactome.org/PathwayBrowser/#/R-SSC-70994 SDH complex dehydrogenates succinate IEA Sus scrofa 16724 R-SSC-880002 https://reactome.org/PathwayBrowser/#/R-SSC-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Sus scrofa 16724 R-SSC-880033 https://reactome.org/PathwayBrowser/#/R-SSC-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Sus scrofa 16724 R-SSC-9855252 https://reactome.org/PathwayBrowser/#/R-SSC-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Sus scrofa 16724 R-XTR-70994 https://reactome.org/PathwayBrowser/#/R-XTR-70994 SDH complex dehydrogenates succinate IEA Xenopus tropicalis 16724 R-XTR-880002 https://reactome.org/PathwayBrowser/#/R-XTR-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Xenopus tropicalis 16724 R-XTR-880033 https://reactome.org/PathwayBrowser/#/R-XTR-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Xenopus tropicalis 16724 R-XTR-9855252 https://reactome.org/PathwayBrowser/#/R-XTR-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Xenopus tropicalis 16728 R-BTA-1482533 https://reactome.org/PathwayBrowser/#/R-BTA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Bos taurus 16728 R-BTA-1482612 https://reactome.org/PathwayBrowser/#/R-BTA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 16728 R-BTA-1482862 https://reactome.org/PathwayBrowser/#/R-BTA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Bos taurus 16728 R-CEL-1482533 https://reactome.org/PathwayBrowser/#/R-CEL-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Caenorhabditis elegans 16728 R-CFA-1482533 https://reactome.org/PathwayBrowser/#/R-CFA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Canis familiaris 16728 R-CFA-1482612 https://reactome.org/PathwayBrowser/#/R-CFA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 16728 R-CFA-1482862 https://reactome.org/PathwayBrowser/#/R-CFA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Canis familiaris 16728 R-DDI-1482533 https://reactome.org/PathwayBrowser/#/R-DDI-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Dictyostelium discoideum 16728 R-DDI-1482612 https://reactome.org/PathwayBrowser/#/R-DDI-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Dictyostelium discoideum 16728 R-DME-1482533 https://reactome.org/PathwayBrowser/#/R-DME-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Drosophila melanogaster 16728 R-DRE-1482533 https://reactome.org/PathwayBrowser/#/R-DRE-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Danio rerio 16728 R-DRE-1482612 https://reactome.org/PathwayBrowser/#/R-DRE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 16728 R-DRE-1482629 https://reactome.org/PathwayBrowser/#/R-DRE-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Danio rerio 16728 R-DRE-1482827 https://reactome.org/PathwayBrowser/#/R-DRE-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Danio rerio 16728 R-DRE-1482862 https://reactome.org/PathwayBrowser/#/R-DRE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Danio rerio 16728 R-GGA-1482533 https://reactome.org/PathwayBrowser/#/R-GGA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus 16728 R-GGA-1482612 https://reactome.org/PathwayBrowser/#/R-GGA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 16728 R-GGA-1482862 https://reactome.org/PathwayBrowser/#/R-GGA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Gallus gallus 16728 R-HSA-1482533 https://reactome.org/PathwayBrowser/#/R-HSA-1482533 2-acyl LPC is acylated to PC by LPCAT TAS Homo sapiens 16728 R-HSA-1482612 https://reactome.org/PathwayBrowser/#/R-HSA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 16728 R-HSA-1482629 https://reactome.org/PathwayBrowser/#/R-HSA-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C TAS Homo sapiens 16728 R-HSA-1482827 https://reactome.org/PathwayBrowser/#/R-HSA-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C TAS Homo sapiens 16728 R-HSA-1482862 https://reactome.org/PathwayBrowser/#/R-HSA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] TAS Homo sapiens 16728 R-MMU-1482533 https://reactome.org/PathwayBrowser/#/R-MMU-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Mus musculus 16728 R-MMU-1482612 https://reactome.org/PathwayBrowser/#/R-MMU-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 16728 R-MMU-1482629 https://reactome.org/PathwayBrowser/#/R-MMU-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Mus musculus 16728 R-MMU-1482827 https://reactome.org/PathwayBrowser/#/R-MMU-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Mus musculus 16728 R-MMU-1482862 https://reactome.org/PathwayBrowser/#/R-MMU-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Mus musculus 16728 R-PFA-1482533 https://reactome.org/PathwayBrowser/#/R-PFA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Plasmodium falciparum 16728 R-RNO-1482533 https://reactome.org/PathwayBrowser/#/R-RNO-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Rattus norvegicus 16728 R-RNO-1482612 https://reactome.org/PathwayBrowser/#/R-RNO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 16728 R-RNO-1482629 https://reactome.org/PathwayBrowser/#/R-RNO-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Rattus norvegicus 16728 R-RNO-1482827 https://reactome.org/PathwayBrowser/#/R-RNO-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Rattus norvegicus 16728 R-RNO-1482862 https://reactome.org/PathwayBrowser/#/R-RNO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Rattus norvegicus 16728 R-SCE-1482533 https://reactome.org/PathwayBrowser/#/R-SCE-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Saccharomyces cerevisiae 16728 R-SCE-1482612 https://reactome.org/PathwayBrowser/#/R-SCE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 16728 R-SCE-1482629 https://reactome.org/PathwayBrowser/#/R-SCE-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Saccharomyces cerevisiae 16728 R-SCE-1482827 https://reactome.org/PathwayBrowser/#/R-SCE-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Saccharomyces cerevisiae 16728 R-SCE-1482862 https://reactome.org/PathwayBrowser/#/R-SCE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Saccharomyces cerevisiae 16728 R-SPO-1482533 https://reactome.org/PathwayBrowser/#/R-SPO-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Schizosaccharomyces pombe 16728 R-SPO-1482612 https://reactome.org/PathwayBrowser/#/R-SPO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 16728 R-SPO-1482629 https://reactome.org/PathwayBrowser/#/R-SPO-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Schizosaccharomyces pombe 16728 R-SPO-1482827 https://reactome.org/PathwayBrowser/#/R-SPO-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Schizosaccharomyces pombe 16728 R-SPO-1482862 https://reactome.org/PathwayBrowser/#/R-SPO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Schizosaccharomyces pombe 16728 R-SSC-1482533 https://reactome.org/PathwayBrowser/#/R-SSC-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Sus scrofa 16728 R-SSC-1482612 https://reactome.org/PathwayBrowser/#/R-SSC-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 16728 R-SSC-1482862 https://reactome.org/PathwayBrowser/#/R-SSC-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Sus scrofa 16728 R-XTR-1482533 https://reactome.org/PathwayBrowser/#/R-XTR-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Xenopus tropicalis 16728 R-XTR-1482612 https://reactome.org/PathwayBrowser/#/R-XTR-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 16728 R-XTR-1482862 https://reactome.org/PathwayBrowser/#/R-XTR-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Xenopus tropicalis 16731 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 16731 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 16731 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 16731 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 16731 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 16731 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 16731 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 16731 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 16731 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 167345 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 167345 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 167345 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 167345 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 167345 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 167345 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 167345 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 167345 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 167345 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 16737 R-BTA-434650 https://reactome.org/PathwayBrowser/#/R-BTA-434650 MATEs mediate extrusion of xenobiotics IEA Bos taurus 16737 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 16737 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 16737 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 16737 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 16737 R-CFA-434650 https://reactome.org/PathwayBrowser/#/R-CFA-434650 MATEs mediate extrusion of xenobiotics IEA Canis familiaris 16737 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 16737 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 16737 R-DDI-434650 https://reactome.org/PathwayBrowser/#/R-DDI-434650 MATEs mediate extrusion of xenobiotics IEA Dictyostelium discoideum 16737 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 16737 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 16737 R-DRE-434650 https://reactome.org/PathwayBrowser/#/R-DRE-434650 MATEs mediate extrusion of xenobiotics IEA Danio rerio 16737 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 16737 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 16737 R-GGA-434650 https://reactome.org/PathwayBrowser/#/R-GGA-434650 MATEs mediate extrusion of xenobiotics IEA Gallus gallus 16737 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 16737 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 16737 R-HSA-434650 https://reactome.org/PathwayBrowser/#/R-HSA-434650 MATEs mediate extrusion of xenobiotics TAS Homo sapiens 16737 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 16737 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 16737 R-HSA-71287 https://reactome.org/PathwayBrowser/#/R-HSA-71287 phosphocreatine + H2O => creatinine + orthophosphate TAS Homo sapiens 16737 R-MMU-434650 https://reactome.org/PathwayBrowser/#/R-MMU-434650 MATEs mediate extrusion of xenobiotics IEA Mus musculus 16737 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 16737 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 16737 R-PFA-434650 https://reactome.org/PathwayBrowser/#/R-PFA-434650 MATEs mediate extrusion of xenobiotics IEA Plasmodium falciparum 16737 R-RNO-434650 https://reactome.org/PathwayBrowser/#/R-RNO-434650 MATEs mediate extrusion of xenobiotics IEA Rattus norvegicus 16737 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 16737 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 16737 R-SCE-434650 https://reactome.org/PathwayBrowser/#/R-SCE-434650 MATEs mediate extrusion of xenobiotics IEA Saccharomyces cerevisiae 16737 R-SPO-434650 https://reactome.org/PathwayBrowser/#/R-SPO-434650 MATEs mediate extrusion of xenobiotics IEA Schizosaccharomyces pombe 16737 R-SSC-434650 https://reactome.org/PathwayBrowser/#/R-SSC-434650 MATEs mediate extrusion of xenobiotics IEA Sus scrofa 16737 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 16737 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 16737 R-XTR-434650 https://reactome.org/PathwayBrowser/#/R-XTR-434650 MATEs mediate extrusion of xenobiotics IEA Xenopus tropicalis 16737 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 16737 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 16750 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 16750 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 16750 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 16750 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16750 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 16750 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 16750 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 16750 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 16750 R-BTA-109539 https://reactome.org/PathwayBrowser/#/R-BTA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Bos taurus 16750 R-BTA-112034 https://reactome.org/PathwayBrowser/#/R-BTA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Bos taurus 16750 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 16750 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 16750 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 16750 R-BTA-74249 https://reactome.org/PathwayBrowser/#/R-BTA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Bos taurus 16750 R-BTA-9824732 https://reactome.org/PathwayBrowser/#/R-BTA-9824732 G or G analog binds C-ter TLR7 dimer IEA Bos taurus 16750 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16750 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 16750 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 16750 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 16750 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 16750 R-CEL-109539 https://reactome.org/PathwayBrowser/#/R-CEL-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Caenorhabditis elegans 16750 R-CEL-112034 https://reactome.org/PathwayBrowser/#/R-CEL-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Caenorhabditis elegans 16750 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 16750 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 16750 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 16750 R-CEL-74249 https://reactome.org/PathwayBrowser/#/R-CEL-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Caenorhabditis elegans 16750 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 16750 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 16750 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 16750 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16750 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 16750 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 16750 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 16750 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 16750 R-CFA-112034 https://reactome.org/PathwayBrowser/#/R-CFA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Canis familiaris 16750 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 16750 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 16750 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 16750 R-CFA-74249 https://reactome.org/PathwayBrowser/#/R-CFA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Canis familiaris 16750 R-CFA-9824732 https://reactome.org/PathwayBrowser/#/R-CFA-9824732 G or G analog binds C-ter TLR7 dimer IEA Canis familiaris 16750 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16750 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 16750 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 16750 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 16750 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 16750 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 16750 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 16750 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 16750 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16750 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 16750 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 16750 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 16750 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 16750 R-DME-109539 https://reactome.org/PathwayBrowser/#/R-DME-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Drosophila melanogaster 16750 R-DME-112034 https://reactome.org/PathwayBrowser/#/R-DME-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Drosophila melanogaster 16750 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 16750 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 16750 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 16750 R-DME-74249 https://reactome.org/PathwayBrowser/#/R-DME-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Drosophila melanogaster 16750 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 16750 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 16750 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 16750 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 16750 R-DRE-112034 https://reactome.org/PathwayBrowser/#/R-DRE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Danio rerio 16750 R-DRE-74249 https://reactome.org/PathwayBrowser/#/R-DRE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Danio rerio 16750 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 16750 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 16750 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 16750 R-GGA-109539 https://reactome.org/PathwayBrowser/#/R-GGA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Gallus gallus 16750 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 16750 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 16750 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 16750 R-GGA-9824732 https://reactome.org/PathwayBrowser/#/R-GGA-9824732 G or G analog binds C-ter TLR7 dimer IEA Gallus gallus 16750 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 16750 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 16750 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 16750 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16750 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 16750 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 16750 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 16750 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 16750 R-HSA-109539 https://reactome.org/PathwayBrowser/#/R-HSA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 TAS Homo sapiens 16750 R-HSA-112034 https://reactome.org/PathwayBrowser/#/R-HSA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine TAS Homo sapiens 16750 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 16750 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 16750 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 16750 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 16750 R-HSA-74249 https://reactome.org/PathwayBrowser/#/R-HSA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 16750 R-HSA-9735789 https://reactome.org/PathwayBrowser/#/R-HSA-9735789 Defective PNP does not convert (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 16750 R-HSA-9824732 https://reactome.org/PathwayBrowser/#/R-HSA-9824732 G or G analog binds C-ter TLR7 dimer TAS Homo sapiens 16750 R-HSA-9824849 https://reactome.org/PathwayBrowser/#/R-HSA-9824849 G or G analog binds C-ter TLR7 GoF variant TAS Homo sapiens 16750 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 16750 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 16750 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 16750 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16750 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 16750 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 16750 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 16750 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 16750 R-MMU-109539 https://reactome.org/PathwayBrowser/#/R-MMU-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Mus musculus 16750 R-MMU-112034 https://reactome.org/PathwayBrowser/#/R-MMU-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Mus musculus 16750 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 16750 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 16750 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 16750 R-MMU-74249 https://reactome.org/PathwayBrowser/#/R-MMU-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Mus musculus 16750 R-MMU-9824732 https://reactome.org/PathwayBrowser/#/R-MMU-9824732 G or G analog binds C-ter TLR7 dimer IEA Mus musculus 16750 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16750 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 16750 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 16750 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 16750 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 16750 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 16750 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 16750 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 16750 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 16750 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16750 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 16750 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 16750 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 16750 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 16750 R-RNO-109539 https://reactome.org/PathwayBrowser/#/R-RNO-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Rattus norvegicus 16750 R-RNO-112034 https://reactome.org/PathwayBrowser/#/R-RNO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Rattus norvegicus 16750 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 16750 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 16750 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 16750 R-RNO-74249 https://reactome.org/PathwayBrowser/#/R-RNO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Rattus norvegicus 16750 R-RNO-9824732 https://reactome.org/PathwayBrowser/#/R-RNO-9824732 G or G analog binds C-ter TLR7 dimer IEA Rattus norvegicus 16750 R-SCE-112034 https://reactome.org/PathwayBrowser/#/R-SCE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Saccharomyces cerevisiae 16750 R-SCE-74249 https://reactome.org/PathwayBrowser/#/R-SCE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Saccharomyces cerevisiae 16750 R-SPO-112034 https://reactome.org/PathwayBrowser/#/R-SPO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Schizosaccharomyces pombe 16750 R-SPO-74249 https://reactome.org/PathwayBrowser/#/R-SPO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Schizosaccharomyces pombe 16750 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 16750 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 16750 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 16750 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16750 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 16750 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 16750 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 16750 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 16750 R-SSC-109539 https://reactome.org/PathwayBrowser/#/R-SSC-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Sus scrofa 16750 R-SSC-112034 https://reactome.org/PathwayBrowser/#/R-SSC-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Sus scrofa 16750 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 16750 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 16750 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 16750 R-SSC-74249 https://reactome.org/PathwayBrowser/#/R-SSC-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Sus scrofa 16750 R-SSC-9824732 https://reactome.org/PathwayBrowser/#/R-SSC-9824732 G or G analog binds C-ter TLR7 dimer IEA Sus scrofa 16750 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 16750 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 16750 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 16750 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 16750 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 16750 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 16750 R-XTR-109539 https://reactome.org/PathwayBrowser/#/R-XTR-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Xenopus tropicalis 16750 R-XTR-112034 https://reactome.org/PathwayBrowser/#/R-XTR-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Xenopus tropicalis 16750 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 16750 R-XTR-74249 https://reactome.org/PathwayBrowser/#/R-XTR-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Xenopus tropicalis 16750 R-XTR-9824732 https://reactome.org/PathwayBrowser/#/R-XTR-9824732 G or G analog binds C-ter TLR7 dimer IEA Xenopus tropicalis 16752 R-BTA-5696408 https://reactome.org/PathwayBrowser/#/R-BTA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Bos taurus 16752 R-BTA-6788611 https://reactome.org/PathwayBrowser/#/R-BTA-6788611 HYKK phosphorylates 5HLYS IEA Bos taurus 16752 R-CEL-5696408 https://reactome.org/PathwayBrowser/#/R-CEL-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Caenorhabditis elegans 16752 R-CFA-5696408 https://reactome.org/PathwayBrowser/#/R-CFA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Canis familiaris 16752 R-CFA-6788611 https://reactome.org/PathwayBrowser/#/R-CFA-6788611 HYKK phosphorylates 5HLYS IEA Canis familiaris 16752 R-DME-5696408 https://reactome.org/PathwayBrowser/#/R-DME-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Drosophila melanogaster 16752 R-DME-6788611 https://reactome.org/PathwayBrowser/#/R-DME-6788611 HYKK phosphorylates 5HLYS IEA Drosophila melanogaster 16752 R-DRE-5696408 https://reactome.org/PathwayBrowser/#/R-DRE-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Danio rerio 16752 R-DRE-6788611 https://reactome.org/PathwayBrowser/#/R-DRE-6788611 HYKK phosphorylates 5HLYS IEA Danio rerio 16752 R-GGA-5696408 https://reactome.org/PathwayBrowser/#/R-GGA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Gallus gallus 16752 R-GGA-6788611 https://reactome.org/PathwayBrowser/#/R-GGA-6788611 HYKK phosphorylates 5HLYS IEA Gallus gallus 16752 R-HSA-5696408 https://reactome.org/PathwayBrowser/#/R-HSA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL TAS Homo sapiens 16752 R-HSA-6788611 https://reactome.org/PathwayBrowser/#/R-HSA-6788611 HYKK phosphorylates 5HLYS TAS Homo sapiens 16752 R-MMU-5696408 https://reactome.org/PathwayBrowser/#/R-MMU-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Mus musculus 16752 R-MMU-6788611 https://reactome.org/PathwayBrowser/#/R-MMU-6788611 HYKK phosphorylates 5HLYS IEA Mus musculus 16752 R-RNO-5696408 https://reactome.org/PathwayBrowser/#/R-RNO-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Rattus norvegicus 16752 R-RNO-6788611 https://reactome.org/PathwayBrowser/#/R-RNO-6788611 HYKK phosphorylates 5HLYS IEA Rattus norvegicus 16752 R-SSC-5696408 https://reactome.org/PathwayBrowser/#/R-SSC-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Sus scrofa 16752 R-SSC-6788611 https://reactome.org/PathwayBrowser/#/R-SSC-6788611 HYKK phosphorylates 5HLYS IEA Sus scrofa 16752 R-XTR-6788611 https://reactome.org/PathwayBrowser/#/R-XTR-6788611 HYKK phosphorylates 5HLYS IEA Xenopus tropicalis 16753 R-BTA-8938300 https://reactome.org/PathwayBrowser/#/R-BTA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Bos taurus 16753 R-BTA-9837419 https://reactome.org/PathwayBrowser/#/R-BTA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Bos taurus 16753 R-CEL-9837419 https://reactome.org/PathwayBrowser/#/R-CEL-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Caenorhabditis elegans 16753 R-CFA-8938300 https://reactome.org/PathwayBrowser/#/R-CFA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Canis familiaris 16753 R-CFA-9837419 https://reactome.org/PathwayBrowser/#/R-CFA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Canis familiaris 16753 R-DDI-8938300 https://reactome.org/PathwayBrowser/#/R-DDI-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Dictyostelium discoideum 16753 R-DDI-9837419 https://reactome.org/PathwayBrowser/#/R-DDI-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Dictyostelium discoideum 16753 R-GGA-8938300 https://reactome.org/PathwayBrowser/#/R-GGA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Gallus gallus 16753 R-GGA-9837419 https://reactome.org/PathwayBrowser/#/R-GGA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Gallus gallus 16753 R-HSA-8938300 https://reactome.org/PathwayBrowser/#/R-HSA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET TAS Homo sapiens 16753 R-HSA-9837419 https://reactome.org/PathwayBrowser/#/R-HSA-9837419 PANK4 hydrolyzes PPANT to pantetheine TAS Homo sapiens 16753 R-MMU-8938300 https://reactome.org/PathwayBrowser/#/R-MMU-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Mus musculus 16753 R-MMU-9837419 https://reactome.org/PathwayBrowser/#/R-MMU-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Mus musculus 16753 R-PFA-9837419 https://reactome.org/PathwayBrowser/#/R-PFA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Plasmodium falciparum 16753 R-RNO-8938300 https://reactome.org/PathwayBrowser/#/R-RNO-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Rattus norvegicus 16753 R-RNO-9837419 https://reactome.org/PathwayBrowser/#/R-RNO-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Rattus norvegicus 16753 R-SCE-9837419 https://reactome.org/PathwayBrowser/#/R-SCE-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Saccharomyces cerevisiae 16753 R-SPO-9837419 https://reactome.org/PathwayBrowser/#/R-SPO-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Schizosaccharomyces pombe 16753 R-SSC-8938300 https://reactome.org/PathwayBrowser/#/R-SSC-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Sus scrofa 16753 R-SSC-9837419 https://reactome.org/PathwayBrowser/#/R-SSC-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Sus scrofa 16753 R-XTR-8938300 https://reactome.org/PathwayBrowser/#/R-XTR-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Xenopus tropicalis 167600 R-BTA-909720 https://reactome.org/PathwayBrowser/#/R-BTA-909720 IFN alpha/beta binds to IFNAR2 IEA Bos taurus 167600 R-BTA-9678561 https://reactome.org/PathwayBrowser/#/R-BTA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Bos taurus 167600 R-BTA-9678935 https://reactome.org/PathwayBrowser/#/R-BTA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Bos taurus 167600 R-CFA-909720 https://reactome.org/PathwayBrowser/#/R-CFA-909720 IFN alpha/beta binds to IFNAR2 IEA Canis familiaris 167600 R-CFA-9678561 https://reactome.org/PathwayBrowser/#/R-CFA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Canis familiaris 167600 R-CFA-9678935 https://reactome.org/PathwayBrowser/#/R-CFA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Canis familiaris 167600 R-DRE-9678561 https://reactome.org/PathwayBrowser/#/R-DRE-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Danio rerio 167600 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus 167600 R-GGA-9678561 https://reactome.org/PathwayBrowser/#/R-GGA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Gallus gallus 167600 R-GGA-9678935 https://reactome.org/PathwayBrowser/#/R-GGA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Gallus gallus 167600 R-HSA-909720 https://reactome.org/PathwayBrowser/#/R-HSA-909720 IFN alpha/beta binds to IFNAR2 TAS Homo sapiens 167600 R-HSA-9678561 https://reactome.org/PathwayBrowser/#/R-HSA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors TAS Homo sapiens 167600 R-HSA-9678935 https://reactome.org/PathwayBrowser/#/R-HSA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors TAS Homo sapiens 167600 R-MMU-909720 https://reactome.org/PathwayBrowser/#/R-MMU-909720 IFN alpha/beta binds to IFNAR2 IEA Mus musculus 167600 R-MMU-9678561 https://reactome.org/PathwayBrowser/#/R-MMU-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Mus musculus 167600 R-MMU-9678935 https://reactome.org/PathwayBrowser/#/R-MMU-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Mus musculus 167600 R-RNO-909720 https://reactome.org/PathwayBrowser/#/R-RNO-909720 IFN alpha/beta binds to IFNAR2 IEA Rattus norvegicus 167600 R-RNO-9678561 https://reactome.org/PathwayBrowser/#/R-RNO-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Rattus norvegicus 167600 R-RNO-9678935 https://reactome.org/PathwayBrowser/#/R-RNO-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Rattus norvegicus 167600 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa 167600 R-SSC-9678561 https://reactome.org/PathwayBrowser/#/R-SSC-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Sus scrofa 167600 R-SSC-9678935 https://reactome.org/PathwayBrowser/#/R-SSC-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Sus scrofa 167600 R-XTR-9678561 https://reactome.org/PathwayBrowser/#/R-XTR-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Xenopus tropicalis 167600 R-XTR-9678935 https://reactome.org/PathwayBrowser/#/R-XTR-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Xenopus tropicalis 167649 R-HSA-9683663 https://reactome.org/PathwayBrowser/#/R-HSA-9683663 N-glycan trimming of Spike TAS Homo sapiens 167649 R-HSA-9686790 https://reactome.org/PathwayBrowser/#/R-HSA-9686790 ER-alpha glucosidases bind ER-alpha glucosidase inhibitors TAS Homo sapiens 167649 R-HSA-9694364 https://reactome.org/PathwayBrowser/#/R-HSA-9694364 N-glycan glucose trimming of Spike TAS Homo sapiens 167650 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 167650 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 167650 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 167650 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 167650 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 167650 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 167650 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 167650 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 167650 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 167650 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 167650 R-HSA-9700646 https://reactome.org/PathwayBrowser/#/R-HSA-9700646 ASP-3026- resistant ALK mutants don't bind ASP-3026 TAS Homo sapiens 167650 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 167650 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 167650 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 167650 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 167650 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 167650 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 167650 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 167651 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 167651 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 167651 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 167652 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 167652 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 167652 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 167653 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 167653 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 167653 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 167653 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 167653 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 167653 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 167653 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 167653 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 167653 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 167653 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 167653 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 167653 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 167653 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 167653 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 167653 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 167653 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 167653 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 167654 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 167654 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 167654 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 167654 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 167654 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 167654 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 167654 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 167654 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 167654 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 167654 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 167654 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 167654 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 167654 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 167654 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 167654 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 167654 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 167654 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 167654 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 167654 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 167654 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 167655 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 167655 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 167655 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 167655 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 167655 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 167655 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 167655 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 167655 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 167655 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 167655 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 167655 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 167655 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 167655 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 167655 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 167655 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 167655 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 167655 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 167655 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 167655 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 167655 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 167655 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 167656 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 167657 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 167657 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 167657 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 167658 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 167658 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 167658 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 167658 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 167658 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 167658 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 167658 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 167658 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 167658 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 167658 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 167658 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 167658 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 167658 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 167658 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 167658 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 167658 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 167658 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 167658 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 167658 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 167658 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 167658 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 167658 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 167658 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 167659 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 167659 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 167659 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus 167659 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 167659 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 167659 R-CEL-9657599 https://reactome.org/PathwayBrowser/#/R-CEL-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Caenorhabditis elegans 167659 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 167659 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 167659 R-CFA-9657599 https://reactome.org/PathwayBrowser/#/R-CFA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Canis familiaris 167659 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 167659 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 167659 R-DME-9657599 https://reactome.org/PathwayBrowser/#/R-DME-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Drosophila melanogaster 167659 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 167659 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 167659 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus 167659 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 167659 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 167659 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 167659 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 167659 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 167659 R-MMU-9657599 https://reactome.org/PathwayBrowser/#/R-MMU-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Mus musculus 167659 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 167659 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 167659 R-RNO-9657599 https://reactome.org/PathwayBrowser/#/R-RNO-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Rattus norvegicus 167659 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 167659 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 167659 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa 167660 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 167660 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 167660 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 167660 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 167660 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 167660 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 167660 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 167660 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 167660 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 167660 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 167660 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 167660 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 167660 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 167660 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 167660 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 167660 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 167660 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 167660 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 167660 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 167660 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 167660 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 167661 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 167661 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 167661 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 167662 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 167662 R-BTA-9653108 https://reactome.org/PathwayBrowser/#/R-BTA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Bos taurus 167662 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 167662 R-CEL-9653108 https://reactome.org/PathwayBrowser/#/R-CEL-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Caenorhabditis elegans 167662 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 167662 R-CFA-9653108 https://reactome.org/PathwayBrowser/#/R-CFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Canis familiaris 167662 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 167662 R-DME-9653108 https://reactome.org/PathwayBrowser/#/R-DME-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Drosophila melanogaster 167662 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 167662 R-GGA-9653108 https://reactome.org/PathwayBrowser/#/R-GGA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Gallus gallus 167662 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 167662 R-HSA-9653108 https://reactome.org/PathwayBrowser/#/R-HSA-9653108 Raf dimer inhibitors bind RAF heterodimers TAS Homo sapiens 167662 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 167662 R-MMU-9653108 https://reactome.org/PathwayBrowser/#/R-MMU-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Mus musculus 167662 R-PFA-9653108 https://reactome.org/PathwayBrowser/#/R-PFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Plasmodium falciparum 167662 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 167662 R-RNO-9653108 https://reactome.org/PathwayBrowser/#/R-RNO-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Rattus norvegicus 167662 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 167662 R-SSC-9653108 https://reactome.org/PathwayBrowser/#/R-SSC-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Sus scrofa 167663 R-HSA-5210912 https://reactome.org/PathwayBrowser/#/R-HSA-5210912 Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) TAS Homo sapiens 167663 R-HSA-5210935 https://reactome.org/PathwayBrowser/#/R-HSA-5210935 Furin cleaves ANTXR1-bound pagA to yield pagA(197-794) TAS Homo sapiens 167663 R-HSA-9683546 https://reactome.org/PathwayBrowser/#/R-HSA-9683546 FURIN binds furin inhibitors TAS Homo sapiens 167664 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 167664 R-BTA-9657603 https://reactome.org/PathwayBrowser/#/R-BTA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Bos taurus 167664 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 167664 R-CEL-9657603 https://reactome.org/PathwayBrowser/#/R-CEL-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Caenorhabditis elegans 167664 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 167664 R-CFA-9657603 https://reactome.org/PathwayBrowser/#/R-CFA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Canis familiaris 167664 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 167664 R-DME-9657603 https://reactome.org/PathwayBrowser/#/R-DME-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Drosophila melanogaster 167664 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 167664 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus 167664 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 167664 R-HSA-9657603 https://reactome.org/PathwayBrowser/#/R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs TAS Homo sapiens 167664 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 167664 R-MMU-9657603 https://reactome.org/PathwayBrowser/#/R-MMU-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Mus musculus 167664 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 167664 R-RNO-9657603 https://reactome.org/PathwayBrowser/#/R-RNO-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Rattus norvegicus 167664 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 167664 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa 167665 R-BTA-9695917 https://reactome.org/PathwayBrowser/#/R-BTA-9695917 SPHK2 binds SPHK2 inhibitors IEA Bos taurus 167665 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 167665 R-CEL-9695917 https://reactome.org/PathwayBrowser/#/R-CEL-9695917 SPHK2 binds SPHK2 inhibitors IEA Caenorhabditis elegans 167665 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 167665 R-CFA-9695917 https://reactome.org/PathwayBrowser/#/R-CFA-9695917 SPHK2 binds SPHK2 inhibitors IEA Canis familiaris 167665 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 167665 R-DDI-9695917 https://reactome.org/PathwayBrowser/#/R-DDI-9695917 SPHK2 binds SPHK2 inhibitors IEA Dictyostelium discoideum 167665 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 167665 R-DME-9695917 https://reactome.org/PathwayBrowser/#/R-DME-9695917 SPHK2 binds SPHK2 inhibitors IEA Drosophila melanogaster 167665 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 167665 R-HSA-9695917 https://reactome.org/PathwayBrowser/#/R-HSA-9695917 SPHK2 binds SPHK2 inhibitors TAS Homo sapiens 167665 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 167665 R-MMU-9695917 https://reactome.org/PathwayBrowser/#/R-MMU-9695917 SPHK2 binds SPHK2 inhibitors IEA Mus musculus 167665 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 167665 R-RNO-9695917 https://reactome.org/PathwayBrowser/#/R-RNO-9695917 SPHK2 binds SPHK2 inhibitors IEA Rattus norvegicus 167665 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 167665 R-SCE-9695917 https://reactome.org/PathwayBrowser/#/R-SCE-9695917 SPHK2 binds SPHK2 inhibitors IEA Saccharomyces cerevisiae 167665 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 167665 R-SPO-9695917 https://reactome.org/PathwayBrowser/#/R-SPO-9695917 SPHK2 binds SPHK2 inhibitors IEA Schizosaccharomyces pombe 167665 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 167665 R-SSC-9695917 https://reactome.org/PathwayBrowser/#/R-SSC-9695917 SPHK2 binds SPHK2 inhibitors IEA Sus scrofa 167665 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 167665 R-XTR-9695917 https://reactome.org/PathwayBrowser/#/R-XTR-9695917 SPHK2 binds SPHK2 inhibitors IEA Xenopus tropicalis 167665 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 167666 R-HSA-9683663 https://reactome.org/PathwayBrowser/#/R-HSA-9683663 N-glycan trimming of Spike TAS Homo sapiens 167666 R-HSA-9686790 https://reactome.org/PathwayBrowser/#/R-HSA-9686790 ER-alpha glucosidases bind ER-alpha glucosidase inhibitors TAS Homo sapiens 167666 R-HSA-9694364 https://reactome.org/PathwayBrowser/#/R-HSA-9694364 N-glycan glucose trimming of Spike TAS Homo sapiens 167667 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 167667 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 167667 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 167667 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 167667 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 167667 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 167667 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 167667 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 167667 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 167667 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 167667 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 167667 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 167667 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 167667 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 167667 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 167667 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 167667 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 167667 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 167667 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 167667 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 167667 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 167667 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 167668 R-BTA-9695917 https://reactome.org/PathwayBrowser/#/R-BTA-9695917 SPHK2 binds SPHK2 inhibitors IEA Bos taurus 167668 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 167668 R-CEL-9695917 https://reactome.org/PathwayBrowser/#/R-CEL-9695917 SPHK2 binds SPHK2 inhibitors IEA Caenorhabditis elegans 167668 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 167668 R-CFA-9695917 https://reactome.org/PathwayBrowser/#/R-CFA-9695917 SPHK2 binds SPHK2 inhibitors IEA Canis familiaris 167668 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 167668 R-DDI-9695917 https://reactome.org/PathwayBrowser/#/R-DDI-9695917 SPHK2 binds SPHK2 inhibitors IEA Dictyostelium discoideum 167668 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 167668 R-DME-9695917 https://reactome.org/PathwayBrowser/#/R-DME-9695917 SPHK2 binds SPHK2 inhibitors IEA Drosophila melanogaster 167668 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 167668 R-HSA-9695917 https://reactome.org/PathwayBrowser/#/R-HSA-9695917 SPHK2 binds SPHK2 inhibitors TAS Homo sapiens 167668 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 167668 R-MMU-9695917 https://reactome.org/PathwayBrowser/#/R-MMU-9695917 SPHK2 binds SPHK2 inhibitors IEA Mus musculus 167668 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 167668 R-RNO-9695917 https://reactome.org/PathwayBrowser/#/R-RNO-9695917 SPHK2 binds SPHK2 inhibitors IEA Rattus norvegicus 167668 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 167668 R-SCE-9695917 https://reactome.org/PathwayBrowser/#/R-SCE-9695917 SPHK2 binds SPHK2 inhibitors IEA Saccharomyces cerevisiae 167668 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 167668 R-SPO-9695917 https://reactome.org/PathwayBrowser/#/R-SPO-9695917 SPHK2 binds SPHK2 inhibitors IEA Schizosaccharomyces pombe 167668 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 167668 R-SSC-9695917 https://reactome.org/PathwayBrowser/#/R-SSC-9695917 SPHK2 binds SPHK2 inhibitors IEA Sus scrofa 167668 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 167668 R-XTR-9695917 https://reactome.org/PathwayBrowser/#/R-XTR-9695917 SPHK2 binds SPHK2 inhibitors IEA Xenopus tropicalis 167668 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 167669 R-BTA-9708759 https://reactome.org/PathwayBrowser/#/R-BTA-9708759 DHODH:FMN binds DHODH inhibitors IEA Bos taurus 167669 R-CEL-9708759 https://reactome.org/PathwayBrowser/#/R-CEL-9708759 DHODH:FMN binds DHODH inhibitors IEA Caenorhabditis elegans 167669 R-CFA-9708759 https://reactome.org/PathwayBrowser/#/R-CFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Canis familiaris 167669 R-DME-9708759 https://reactome.org/PathwayBrowser/#/R-DME-9708759 DHODH:FMN binds DHODH inhibitors IEA Drosophila melanogaster 167669 R-DRE-9708759 https://reactome.org/PathwayBrowser/#/R-DRE-9708759 DHODH:FMN binds DHODH inhibitors IEA Danio rerio 167669 R-GGA-9708759 https://reactome.org/PathwayBrowser/#/R-GGA-9708759 DHODH:FMN binds DHODH inhibitors IEA Gallus gallus 167669 R-HSA-9708759 https://reactome.org/PathwayBrowser/#/R-HSA-9708759 DHODH:FMN binds DHODH inhibitors TAS Homo sapiens 167669 R-MMU-9708759 https://reactome.org/PathwayBrowser/#/R-MMU-9708759 DHODH:FMN binds DHODH inhibitors IEA Mus musculus 167669 R-PFA-9708759 https://reactome.org/PathwayBrowser/#/R-PFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Plasmodium falciparum 167669 R-RNO-9708759 https://reactome.org/PathwayBrowser/#/R-RNO-9708759 DHODH:FMN binds DHODH inhibitors IEA Rattus norvegicus 167669 R-SPO-9708759 https://reactome.org/PathwayBrowser/#/R-SPO-9708759 DHODH:FMN binds DHODH inhibitors IEA Schizosaccharomyces pombe 167669 R-SSC-9708759 https://reactome.org/PathwayBrowser/#/R-SSC-9708759 DHODH:FMN binds DHODH inhibitors IEA Sus scrofa 167669 R-XTR-9708759 https://reactome.org/PathwayBrowser/#/R-XTR-9708759 DHODH:FMN binds DHODH inhibitors IEA Xenopus tropicalis 167670 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 167670 R-BTA-9657603 https://reactome.org/PathwayBrowser/#/R-BTA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Bos taurus 167670 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 167670 R-CEL-9657603 https://reactome.org/PathwayBrowser/#/R-CEL-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Caenorhabditis elegans 167670 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 167670 R-CFA-9657603 https://reactome.org/PathwayBrowser/#/R-CFA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Canis familiaris 167670 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 167670 R-DME-9657603 https://reactome.org/PathwayBrowser/#/R-DME-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Drosophila melanogaster 167670 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 167670 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus 167670 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 167670 R-HSA-9657603 https://reactome.org/PathwayBrowser/#/R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs TAS Homo sapiens 167670 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 167670 R-MMU-9657603 https://reactome.org/PathwayBrowser/#/R-MMU-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Mus musculus 167670 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 167670 R-RNO-9657603 https://reactome.org/PathwayBrowser/#/R-RNO-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Rattus norvegicus 167670 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 167670 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa 167671 R-BTA-9695917 https://reactome.org/PathwayBrowser/#/R-BTA-9695917 SPHK2 binds SPHK2 inhibitors IEA Bos taurus 167671 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 167671 R-CEL-9695917 https://reactome.org/PathwayBrowser/#/R-CEL-9695917 SPHK2 binds SPHK2 inhibitors IEA Caenorhabditis elegans 167671 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 167671 R-CFA-9695917 https://reactome.org/PathwayBrowser/#/R-CFA-9695917 SPHK2 binds SPHK2 inhibitors IEA Canis familiaris 167671 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 167671 R-DDI-9695917 https://reactome.org/PathwayBrowser/#/R-DDI-9695917 SPHK2 binds SPHK2 inhibitors IEA Dictyostelium discoideum 167671 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 167671 R-DME-9695917 https://reactome.org/PathwayBrowser/#/R-DME-9695917 SPHK2 binds SPHK2 inhibitors IEA Drosophila melanogaster 167671 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 167671 R-HSA-9695917 https://reactome.org/PathwayBrowser/#/R-HSA-9695917 SPHK2 binds SPHK2 inhibitors TAS Homo sapiens 167671 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 167671 R-MMU-9695917 https://reactome.org/PathwayBrowser/#/R-MMU-9695917 SPHK2 binds SPHK2 inhibitors IEA Mus musculus 167671 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 167671 R-RNO-9695917 https://reactome.org/PathwayBrowser/#/R-RNO-9695917 SPHK2 binds SPHK2 inhibitors IEA Rattus norvegicus 167671 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 167671 R-SCE-9695917 https://reactome.org/PathwayBrowser/#/R-SCE-9695917 SPHK2 binds SPHK2 inhibitors IEA Saccharomyces cerevisiae 167671 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 167671 R-SPO-9695917 https://reactome.org/PathwayBrowser/#/R-SPO-9695917 SPHK2 binds SPHK2 inhibitors IEA Schizosaccharomyces pombe 167671 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 167671 R-SSC-9695917 https://reactome.org/PathwayBrowser/#/R-SSC-9695917 SPHK2 binds SPHK2 inhibitors IEA Sus scrofa 167671 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 167671 R-XTR-9695917 https://reactome.org/PathwayBrowser/#/R-XTR-9695917 SPHK2 binds SPHK2 inhibitors IEA Xenopus tropicalis 167671 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 167672 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 167672 R-BTA-9653108 https://reactome.org/PathwayBrowser/#/R-BTA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Bos taurus 167672 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 167672 R-CEL-9653108 https://reactome.org/PathwayBrowser/#/R-CEL-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Caenorhabditis elegans 167672 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 167672 R-CFA-9653108 https://reactome.org/PathwayBrowser/#/R-CFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Canis familiaris 167672 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 167672 R-DME-9653108 https://reactome.org/PathwayBrowser/#/R-DME-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Drosophila melanogaster 167672 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 167672 R-GGA-9653108 https://reactome.org/PathwayBrowser/#/R-GGA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Gallus gallus 167672 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 167672 R-HSA-9653108 https://reactome.org/PathwayBrowser/#/R-HSA-9653108 Raf dimer inhibitors bind RAF heterodimers TAS Homo sapiens 167672 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 167672 R-MMU-9653108 https://reactome.org/PathwayBrowser/#/R-MMU-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Mus musculus 167672 R-PFA-9653108 https://reactome.org/PathwayBrowser/#/R-PFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Plasmodium falciparum 167672 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 167672 R-RNO-9653108 https://reactome.org/PathwayBrowser/#/R-RNO-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Rattus norvegicus 167672 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 167672 R-SSC-9653108 https://reactome.org/PathwayBrowser/#/R-SSC-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Sus scrofa 167673 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 167673 R-BTA-9653108 https://reactome.org/PathwayBrowser/#/R-BTA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Bos taurus 167673 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 167673 R-CEL-9653108 https://reactome.org/PathwayBrowser/#/R-CEL-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Caenorhabditis elegans 167673 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 167673 R-CFA-9653108 https://reactome.org/PathwayBrowser/#/R-CFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Canis familiaris 167673 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 167673 R-DME-9653108 https://reactome.org/PathwayBrowser/#/R-DME-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Drosophila melanogaster 167673 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 167673 R-GGA-9653108 https://reactome.org/PathwayBrowser/#/R-GGA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Gallus gallus 167673 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 167673 R-HSA-9653108 https://reactome.org/PathwayBrowser/#/R-HSA-9653108 Raf dimer inhibitors bind RAF heterodimers TAS Homo sapiens 167673 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 167673 R-MMU-9653108 https://reactome.org/PathwayBrowser/#/R-MMU-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Mus musculus 167673 R-PFA-9653108 https://reactome.org/PathwayBrowser/#/R-PFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Plasmodium falciparum 167673 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 167673 R-RNO-9653108 https://reactome.org/PathwayBrowser/#/R-RNO-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Rattus norvegicus 167673 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 167673 R-SSC-9653108 https://reactome.org/PathwayBrowser/#/R-SSC-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Sus scrofa 167674 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 167674 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 167674 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 167674 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 167674 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 167674 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 167674 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 167674 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 167674 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 167674 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 167674 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 167674 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 167674 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 167674 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 167674 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 167674 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 167674 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 167674 R-HSA-9665315 https://reactome.org/PathwayBrowser/#/R-HSA-9665315 ERBB2 T733I does not bind tesevatinib TAS Homo sapiens 167674 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 167674 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 167674 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 167674 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 167674 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 167674 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 16768 R-HSA-1222583 https://reactome.org/PathwayBrowser/#/R-HSA-1222583 MscR reduces nitrosomycothiol to ammonia TAS Homo sapiens 16768 R-HSA-1222594 https://reactome.org/PathwayBrowser/#/R-HSA-1222594 Mycothiol scavenges nitrosyl TAS Homo sapiens 16768 R-MTU-879245 https://reactome.org/PathwayBrowser/#/R-MTU-879245 mycothiol binds formaldehyde and is dehydrogenated TAS Mycobacterium tuberculosis 16768 R-MTU-879248 https://reactome.org/PathwayBrowser/#/R-MTU-879248 desacetylmycothiol is acetylated to mycothiol using acetyl-CoA TAS Mycobacterium tuberculosis 16768 R-MTU-879266 https://reactome.org/PathwayBrowser/#/R-MTU-879266 mycothiol is oxidized to mycothione TAS Mycobacterium tuberculosis 16768 R-MTU-879273 https://reactome.org/PathwayBrowser/#/R-MTU-879273 mycothiol conjugates with electrophilic xenobiotic TAS Mycobacterium tuberculosis 16768 R-MTU-879281 https://reactome.org/PathwayBrowser/#/R-MTU-879281 mycothiol is cleaved to acetylcysteine and glucosaminylinositol TAS Mycobacterium tuberculosis 16768 R-MTU-879293 https://reactome.org/PathwayBrowser/#/R-MTU-879293 formylmycothiol hydrolyzes into mycothiol and formate TAS Mycobacterium tuberculosis 16768 R-MTU-879322 https://reactome.org/PathwayBrowser/#/R-MTU-879322 mycothione is reduced to mycothiol TAS Mycobacterium tuberculosis 16796 R-BTA-209821 https://reactome.org/PathwayBrowser/#/R-BTA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Bos taurus 16796 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 16796 R-BTA-419334 https://reactome.org/PathwayBrowser/#/R-BTA-419334 Melatonin receptors can bind melatonin IEA Bos taurus 16796 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 16796 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 16796 R-BTA-8936519 https://reactome.org/PathwayBrowser/#/R-BTA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Bos taurus 16796 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 16796 R-CEL-419334 https://reactome.org/PathwayBrowser/#/R-CEL-419334 Melatonin receptors can bind melatonin IEA Caenorhabditis elegans 16796 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 16796 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 16796 R-CFA-209821 https://reactome.org/PathwayBrowser/#/R-CFA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Canis familiaris 16796 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 16796 R-CFA-419334 https://reactome.org/PathwayBrowser/#/R-CFA-419334 Melatonin receptors can bind melatonin IEA Canis familiaris 16796 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 16796 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 16796 R-CFA-8936519 https://reactome.org/PathwayBrowser/#/R-CFA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Canis familiaris 16796 R-DDI-209821 https://reactome.org/PathwayBrowser/#/R-DDI-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Dictyostelium discoideum 16796 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 16796 R-DME-419334 https://reactome.org/PathwayBrowser/#/R-DME-419334 Melatonin receptors can bind melatonin IEA Drosophila melanogaster 16796 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 16796 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 16796 R-DRE-209821 https://reactome.org/PathwayBrowser/#/R-DRE-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Danio rerio 16796 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 16796 R-DRE-419334 https://reactome.org/PathwayBrowser/#/R-DRE-419334 Melatonin receptors can bind melatonin IEA Danio rerio 16796 R-GGA-209821 https://reactome.org/PathwayBrowser/#/R-GGA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Gallus gallus 16796 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 16796 R-GGA-419334 https://reactome.org/PathwayBrowser/#/R-GGA-419334 Melatonin receptors can bind melatonin IEA Gallus gallus 16796 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 16796 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 16796 R-GGA-8936519 https://reactome.org/PathwayBrowser/#/R-GGA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Gallus gallus 16796 R-HSA-209821 https://reactome.org/PathwayBrowser/#/R-HSA-209821 Methylation of N-acetyl-5-HT to form melatonin TAS Homo sapiens 16796 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 16796 R-HSA-419334 https://reactome.org/PathwayBrowser/#/R-HSA-419334 Melatonin receptors can bind melatonin TAS Homo sapiens 16796 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 16796 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 16796 R-HSA-8936519 https://reactome.org/PathwayBrowser/#/R-HSA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones TAS Homo sapiens 16796 R-MMU-209821 https://reactome.org/PathwayBrowser/#/R-MMU-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Mus musculus 16796 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 16796 R-MMU-419334 https://reactome.org/PathwayBrowser/#/R-MMU-419334 Melatonin receptors can bind melatonin IEA Mus musculus 16796 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 16796 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 16796 R-MMU-8936519 https://reactome.org/PathwayBrowser/#/R-MMU-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Mus musculus 16796 R-RNO-209821 https://reactome.org/PathwayBrowser/#/R-RNO-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Rattus norvegicus 16796 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 16796 R-RNO-419334 https://reactome.org/PathwayBrowser/#/R-RNO-419334 Melatonin receptors can bind melatonin IEA Rattus norvegicus 16796 R-RNO-8936519 https://reactome.org/PathwayBrowser/#/R-RNO-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Rattus norvegicus 16796 R-SSC-209821 https://reactome.org/PathwayBrowser/#/R-SSC-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Sus scrofa 16796 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 16796 R-SSC-419334 https://reactome.org/PathwayBrowser/#/R-SSC-419334 Melatonin receptors can bind melatonin IEA Sus scrofa 16796 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 16796 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 16796 R-SSC-8936519 https://reactome.org/PathwayBrowser/#/R-SSC-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Sus scrofa 16796 R-XTR-209821 https://reactome.org/PathwayBrowser/#/R-XTR-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Xenopus tropicalis 16796 R-XTR-8936519 https://reactome.org/PathwayBrowser/#/R-XTR-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Xenopus tropicalis 16797 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 16797 R-BTA-5359451 https://reactome.org/PathwayBrowser/#/R-BTA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Bos taurus 16797 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 16797 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 16797 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 16797 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 16797 R-CEL-5359451 https://reactome.org/PathwayBrowser/#/R-CEL-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Caenorhabditis elegans 16797 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 16797 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 16797 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 16797 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 16797 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 16797 R-CFA-5359451 https://reactome.org/PathwayBrowser/#/R-CFA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Canis familiaris 16797 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 16797 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 16797 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 16797 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 16797 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 16797 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 16797 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 16797 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 16797 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 16797 R-DRE-5359451 https://reactome.org/PathwayBrowser/#/R-DRE-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Danio rerio 16797 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 16797 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 16797 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 16797 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 16797 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 16797 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 16797 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 16797 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 16797 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 16797 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 16797 R-HSA-2408544 https://reactome.org/PathwayBrowser/#/R-HSA-2408544 AdoSeMet is converted to AdeSeHCys by MetTrans(1) IEA Homo sapiens 16797 R-HSA-5359451 https://reactome.org/PathwayBrowser/#/R-HSA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA TAS Homo sapiens 16797 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 16797 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 16797 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 16797 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 16797 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 16797 R-MMU-5359451 https://reactome.org/PathwayBrowser/#/R-MMU-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Mus musculus 16797 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 16797 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 16797 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 16797 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 16797 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 16797 R-RNO-2408545 https://reactome.org/PathwayBrowser/#/R-RNO-2408545 AdoSeMet is converted to AdeSeHCys by MetTrans(2) TAS Rattus norvegicus 16797 R-RNO-5359451 https://reactome.org/PathwayBrowser/#/R-RNO-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Rattus norvegicus 16797 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 16797 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 16797 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 16797 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 16797 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 16797 R-SSC-5359451 https://reactome.org/PathwayBrowser/#/R-SSC-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Sus scrofa 16797 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 16797 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 16797 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 16797 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 16797 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 16797 R-XTR-5359451 https://reactome.org/PathwayBrowser/#/R-XTR-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Xenopus tropicalis 16797 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 16797 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 16797 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 16797 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 16802 R-BTA-8959719 https://reactome.org/PathwayBrowser/#/R-BTA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Bos taurus 16802 R-CEL-8959719 https://reactome.org/PathwayBrowser/#/R-CEL-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Caenorhabditis elegans 16802 R-CFA-8959719 https://reactome.org/PathwayBrowser/#/R-CFA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Canis familiaris 16802 R-GGA-8959719 https://reactome.org/PathwayBrowser/#/R-GGA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Gallus gallus 16802 R-HSA-8959719 https://reactome.org/PathwayBrowser/#/R-HSA-8959719 SHPK phosphorylates Sedo to Sedo7P TAS Homo sapiens 16802 R-MMU-8959719 https://reactome.org/PathwayBrowser/#/R-MMU-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Mus musculus 16802 R-RNO-8959719 https://reactome.org/PathwayBrowser/#/R-RNO-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Rattus norvegicus 16802 R-SSC-8959719 https://reactome.org/PathwayBrowser/#/R-SSC-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Sus scrofa 16802 R-XTR-8959719 https://reactome.org/PathwayBrowser/#/R-XTR-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Xenopus tropicalis 16810 R-BTA-1234164 https://reactome.org/PathwayBrowser/#/R-BTA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Bos taurus 16810 R-BTA-1234165 https://reactome.org/PathwayBrowser/#/R-BTA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Bos taurus 16810 R-BTA-1234173 https://reactome.org/PathwayBrowser/#/R-BTA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Bos taurus 16810 R-BTA-1234177 https://reactome.org/PathwayBrowser/#/R-BTA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Bos taurus 16810 R-BTA-1234181 https://reactome.org/PathwayBrowser/#/R-BTA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Bos taurus 16810 R-BTA-1650808 https://reactome.org/PathwayBrowser/#/R-BTA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Bos taurus 16810 R-BTA-1980233 https://reactome.org/PathwayBrowser/#/R-BTA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Bos taurus 16810 R-BTA-1981104 https://reactome.org/PathwayBrowser/#/R-BTA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Bos taurus 16810 R-BTA-198440 https://reactome.org/PathwayBrowser/#/R-BTA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Bos taurus 16810 R-BTA-2172678 https://reactome.org/PathwayBrowser/#/R-BTA-2172678 PHF8 demethylates histone H4K20me1 IEA Bos taurus 16810 R-BTA-3222593 https://reactome.org/PathwayBrowser/#/R-BTA-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Bos taurus 16810 R-BTA-372480 https://reactome.org/PathwayBrowser/#/R-BTA-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Bos taurus 16810 R-BTA-376851 https://reactome.org/PathwayBrowser/#/R-BTA-376851 SLC25A11 exchanges 2-OG and MAL IEA Bos taurus 16810 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 16810 R-BTA-389540 https://reactome.org/PathwayBrowser/#/R-BTA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 16810 R-BTA-389550 https://reactome.org/PathwayBrowser/#/R-BTA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 16810 R-BTA-389639 https://reactome.org/PathwayBrowser/#/R-BTA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Bos taurus 16810 R-BTA-450984 https://reactome.org/PathwayBrowser/#/R-BTA-450984 IDH2 dimer decarboxylates isocitrate IEA Bos taurus 16810 R-BTA-4722133 https://reactome.org/PathwayBrowser/#/R-BTA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Bos taurus 16810 R-BTA-4724279 https://reactome.org/PathwayBrowser/#/R-BTA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Bos taurus 16810 R-BTA-4724284 https://reactome.org/PathwayBrowser/#/R-BTA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Bos taurus 16810 R-BTA-4754176 https://reactome.org/PathwayBrowser/#/R-BTA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Bos taurus 16810 R-BTA-4754181 https://reactome.org/PathwayBrowser/#/R-BTA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Bos taurus 16810 R-BTA-4754187 https://reactome.org/PathwayBrowser/#/R-BTA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Bos taurus 16810 R-BTA-507749 https://reactome.org/PathwayBrowser/#/R-BTA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Bos taurus 16810 R-BTA-507775 https://reactome.org/PathwayBrowser/#/R-BTA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Bos taurus 16810 R-BTA-508179 https://reactome.org/PathwayBrowser/#/R-BTA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Bos taurus 16810 R-BTA-508189 https://reactome.org/PathwayBrowser/#/R-BTA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Bos taurus 16810 R-BTA-508561 https://reactome.org/PathwayBrowser/#/R-BTA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Bos taurus 16810 R-BTA-517444 https://reactome.org/PathwayBrowser/#/R-BTA-517444 TAT aminates HPP IEA Bos taurus 16810 R-BTA-5423117 https://reactome.org/PathwayBrowser/#/R-BTA-5423117 PHF8 demethylates MeK21-histone H4 IEA Bos taurus 16810 R-BTA-561041 https://reactome.org/PathwayBrowser/#/R-BTA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Bos taurus 16810 R-BTA-561059 https://reactome.org/PathwayBrowser/#/R-BTA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Bos taurus 16810 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 16810 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 16810 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 16810 R-BTA-5661114 https://reactome.org/PathwayBrowser/#/R-BTA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Bos taurus 16810 R-BTA-5661115 https://reactome.org/PathwayBrowser/#/R-BTA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Bos taurus 16810 R-BTA-5661116 https://reactome.org/PathwayBrowser/#/R-BTA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Bos taurus 16810 R-BTA-5661120 https://reactome.org/PathwayBrowser/#/R-BTA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Bos taurus 16810 R-BTA-5661121 https://reactome.org/PathwayBrowser/#/R-BTA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Bos taurus 16810 R-BTA-5661122 https://reactome.org/PathwayBrowser/#/R-BTA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Bos taurus 16810 R-BTA-5661124 https://reactome.org/PathwayBrowser/#/R-BTA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Bos taurus 16810 R-BTA-5661125 https://reactome.org/PathwayBrowser/#/R-BTA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Bos taurus 16810 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 16810 R-BTA-70523 https://reactome.org/PathwayBrowser/#/R-BTA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Bos taurus 16810 R-BTA-70524 https://reactome.org/PathwayBrowser/#/R-BTA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Bos taurus 16810 R-BTA-70581 https://reactome.org/PathwayBrowser/#/R-BTA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Bos taurus 16810 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Bos taurus 16810 R-BTA-70592 https://reactome.org/PathwayBrowser/#/R-BTA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Bos taurus 16810 R-BTA-70596 https://reactome.org/PathwayBrowser/#/R-BTA-70596 GOT2 dimer deaminates L-Asp IEA Bos taurus 16810 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Bos taurus 16810 R-BTA-70613 https://reactome.org/PathwayBrowser/#/R-BTA-70613 GOT2 transaminates OA and L-Glu IEA Bos taurus 16810 R-BTA-70654 https://reactome.org/PathwayBrowser/#/R-BTA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Bos taurus 16810 R-BTA-70666 https://reactome.org/PathwayBrowser/#/R-BTA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Bos taurus 16810 R-BTA-70723 https://reactome.org/PathwayBrowser/#/R-BTA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Bos taurus 16810 R-BTA-70724 https://reactome.org/PathwayBrowser/#/R-BTA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Bos taurus 16810 R-BTA-70938 https://reactome.org/PathwayBrowser/#/R-BTA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Bos taurus 16810 R-BTA-70952 https://reactome.org/PathwayBrowser/#/R-BTA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Bos taurus 16810 R-BTA-70967 https://reactome.org/PathwayBrowser/#/R-BTA-70967 IDH3 complex decarboxylates isocitrate IEA Bos taurus 16810 R-BTA-71155 https://reactome.org/PathwayBrowser/#/R-BTA-71155 TAT deaminates tyrosine IEA Bos taurus 16810 R-BTA-71241 https://reactome.org/PathwayBrowser/#/R-BTA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Bos taurus 16810 R-BTA-71261 https://reactome.org/PathwayBrowser/#/R-BTA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Bos taurus 16810 R-BTA-71401 https://reactome.org/PathwayBrowser/#/R-BTA-71401 OGDH dimer decarboxylates 2-OG IEA Bos taurus 16810 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 16810 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 16810 R-BTA-880002 https://reactome.org/PathwayBrowser/#/R-BTA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Bos taurus 16810 R-BTA-880007 https://reactome.org/PathwayBrowser/#/R-BTA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Bos taurus 16810 R-BTA-880033 https://reactome.org/PathwayBrowser/#/R-BTA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Bos taurus 16810 R-BTA-880050 https://reactome.org/PathwayBrowser/#/R-BTA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Bos taurus 16810 R-BTA-8857692 https://reactome.org/PathwayBrowser/#/R-BTA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Bos taurus 16810 R-BTA-893583 https://reactome.org/PathwayBrowser/#/R-BTA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Bos taurus 16810 R-BTA-916855 https://reactome.org/PathwayBrowser/#/R-BTA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Bos taurus 16810 R-BTA-9629578 https://reactome.org/PathwayBrowser/#/R-BTA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Bos taurus 16810 R-BTA-9629591 https://reactome.org/PathwayBrowser/#/R-BTA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Bos taurus 16810 R-BTA-9629869 https://reactome.org/PathwayBrowser/#/R-BTA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Bos taurus 16810 R-BTA-9629888 https://reactome.org/PathwayBrowser/#/R-BTA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Bos taurus 16810 R-BTA-9629946 https://reactome.org/PathwayBrowser/#/R-BTA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Bos taurus 16810 R-BTA-9630022 https://reactome.org/PathwayBrowser/#/R-BTA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Bos taurus 16810 R-BTA-9630769 https://reactome.org/PathwayBrowser/#/R-BTA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Bos taurus 16810 R-BTA-9630967 https://reactome.org/PathwayBrowser/#/R-BTA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Bos taurus 16810 R-BTA-9630993 https://reactome.org/PathwayBrowser/#/R-BTA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Bos taurus 16810 R-BTA-9631356 https://reactome.org/PathwayBrowser/#/R-BTA-9631356 ASPH:Fe2+ hydroxylates an aspartate residue of F9 TAS Bos taurus 16810 R-BTA-964773 https://reactome.org/PathwayBrowser/#/R-BTA-964773 OXGR1 binds 2OG IEA Bos taurus 16810 R-BTA-977333 https://reactome.org/PathwayBrowser/#/R-BTA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Bos taurus 16810 R-CEL-1234165 https://reactome.org/PathwayBrowser/#/R-CEL-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 16810 R-CEL-1234173 https://reactome.org/PathwayBrowser/#/R-CEL-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 16810 R-CEL-1234177 https://reactome.org/PathwayBrowser/#/R-CEL-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 16810 R-CEL-1234181 https://reactome.org/PathwayBrowser/#/R-CEL-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 16810 R-CEL-1650808 https://reactome.org/PathwayBrowser/#/R-CEL-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Caenorhabditis elegans 16810 R-CEL-1981104 https://reactome.org/PathwayBrowser/#/R-CEL-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Caenorhabditis elegans 16810 R-CEL-198440 https://reactome.org/PathwayBrowser/#/R-CEL-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Caenorhabditis elegans 16810 R-CEL-2172678 https://reactome.org/PathwayBrowser/#/R-CEL-2172678 PHF8 demethylates histone H4K20me1 IEA Caenorhabditis elegans 16810 R-CEL-3222593 https://reactome.org/PathwayBrowser/#/R-CEL-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Caenorhabditis elegans 16810 R-CEL-372480 https://reactome.org/PathwayBrowser/#/R-CEL-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Caenorhabditis elegans 16810 R-CEL-376851 https://reactome.org/PathwayBrowser/#/R-CEL-376851 SLC25A11 exchanges 2-OG and MAL IEA Caenorhabditis elegans 16810 R-CEL-389540 https://reactome.org/PathwayBrowser/#/R-CEL-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 16810 R-CEL-389550 https://reactome.org/PathwayBrowser/#/R-CEL-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 16810 R-CEL-389639 https://reactome.org/PathwayBrowser/#/R-CEL-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Caenorhabditis elegans 16810 R-CEL-450984 https://reactome.org/PathwayBrowser/#/R-CEL-450984 IDH2 dimer decarboxylates isocitrate IEA Caenorhabditis elegans 16810 R-CEL-4722133 https://reactome.org/PathwayBrowser/#/R-CEL-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-4724279 https://reactome.org/PathwayBrowser/#/R-CEL-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-4724284 https://reactome.org/PathwayBrowser/#/R-CEL-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-4754176 https://reactome.org/PathwayBrowser/#/R-CEL-4754176 JMJD6 demethylates MeR3-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-4754181 https://reactome.org/PathwayBrowser/#/R-CEL-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-4754187 https://reactome.org/PathwayBrowser/#/R-CEL-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-507749 https://reactome.org/PathwayBrowser/#/R-CEL-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Caenorhabditis elegans 16810 R-CEL-507775 https://reactome.org/PathwayBrowser/#/R-CEL-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Caenorhabditis elegans 16810 R-CEL-508179 https://reactome.org/PathwayBrowser/#/R-CEL-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Caenorhabditis elegans 16810 R-CEL-508189 https://reactome.org/PathwayBrowser/#/R-CEL-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Caenorhabditis elegans 16810 R-CEL-517444 https://reactome.org/PathwayBrowser/#/R-CEL-517444 TAT aminates HPP IEA Caenorhabditis elegans 16810 R-CEL-5423117 https://reactome.org/PathwayBrowser/#/R-CEL-5423117 PHF8 demethylates MeK21-histone H4 IEA Caenorhabditis elegans 16810 R-CEL-561041 https://reactome.org/PathwayBrowser/#/R-CEL-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Caenorhabditis elegans 16810 R-CEL-561059 https://reactome.org/PathwayBrowser/#/R-CEL-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Caenorhabditis elegans 16810 R-CEL-5661114 https://reactome.org/PathwayBrowser/#/R-CEL-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-5661115 https://reactome.org/PathwayBrowser/#/R-CEL-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-5661116 https://reactome.org/PathwayBrowser/#/R-CEL-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-5661120 https://reactome.org/PathwayBrowser/#/R-CEL-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-5661121 https://reactome.org/PathwayBrowser/#/R-CEL-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-5661122 https://reactome.org/PathwayBrowser/#/R-CEL-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Caenorhabditis elegans 16810 R-CEL-5661124 https://reactome.org/PathwayBrowser/#/R-CEL-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Caenorhabditis elegans 16810 R-CEL-5661125 https://reactome.org/PathwayBrowser/#/R-CEL-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Caenorhabditis elegans 16810 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 16810 R-CEL-70523 https://reactome.org/PathwayBrowser/#/R-CEL-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Caenorhabditis elegans 16810 R-CEL-70524 https://reactome.org/PathwayBrowser/#/R-CEL-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Caenorhabditis elegans 16810 R-CEL-70581 https://reactome.org/PathwayBrowser/#/R-CEL-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Caenorhabditis elegans 16810 R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Caenorhabditis elegans 16810 R-CEL-70592 https://reactome.org/PathwayBrowser/#/R-CEL-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Caenorhabditis elegans 16810 R-CEL-70596 https://reactome.org/PathwayBrowser/#/R-CEL-70596 GOT2 dimer deaminates L-Asp IEA Caenorhabditis elegans 16810 R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Caenorhabditis elegans 16810 R-CEL-70613 https://reactome.org/PathwayBrowser/#/R-CEL-70613 GOT2 transaminates OA and L-Glu IEA Caenorhabditis elegans 16810 R-CEL-70654 https://reactome.org/PathwayBrowser/#/R-CEL-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Caenorhabditis elegans 16810 R-CEL-70666 https://reactome.org/PathwayBrowser/#/R-CEL-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Caenorhabditis elegans 16810 R-CEL-70723 https://reactome.org/PathwayBrowser/#/R-CEL-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Caenorhabditis elegans 16810 R-CEL-70724 https://reactome.org/PathwayBrowser/#/R-CEL-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Caenorhabditis elegans 16810 R-CEL-70938 https://reactome.org/PathwayBrowser/#/R-CEL-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Caenorhabditis elegans 16810 R-CEL-70967 https://reactome.org/PathwayBrowser/#/R-CEL-70967 IDH3 complex decarboxylates isocitrate IEA Caenorhabditis elegans 16810 R-CEL-71155 https://reactome.org/PathwayBrowser/#/R-CEL-71155 TAT deaminates tyrosine IEA Caenorhabditis elegans 16810 R-CEL-71241 https://reactome.org/PathwayBrowser/#/R-CEL-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Caenorhabditis elegans 16810 R-CEL-71261 https://reactome.org/PathwayBrowser/#/R-CEL-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Caenorhabditis elegans 16810 R-CEL-71401 https://reactome.org/PathwayBrowser/#/R-CEL-71401 OGDH dimer decarboxylates 2-OG IEA Caenorhabditis elegans 16810 R-CEL-880002 https://reactome.org/PathwayBrowser/#/R-CEL-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Caenorhabditis elegans 16810 R-CEL-880007 https://reactome.org/PathwayBrowser/#/R-CEL-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Caenorhabditis elegans 16810 R-CEL-880033 https://reactome.org/PathwayBrowser/#/R-CEL-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Caenorhabditis elegans 16810 R-CEL-880050 https://reactome.org/PathwayBrowser/#/R-CEL-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Caenorhabditis elegans 16810 R-CEL-916855 https://reactome.org/PathwayBrowser/#/R-CEL-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Caenorhabditis elegans 16810 R-CEL-9629869 https://reactome.org/PathwayBrowser/#/R-CEL-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Caenorhabditis elegans 16810 R-CEL-9629888 https://reactome.org/PathwayBrowser/#/R-CEL-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Caenorhabditis elegans 16810 R-CEL-9629946 https://reactome.org/PathwayBrowser/#/R-CEL-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Caenorhabditis elegans 16810 R-CEL-9630022 https://reactome.org/PathwayBrowser/#/R-CEL-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Caenorhabditis elegans 16810 R-CEL-9630769 https://reactome.org/PathwayBrowser/#/R-CEL-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Caenorhabditis elegans 16810 R-CEL-9630993 https://reactome.org/PathwayBrowser/#/R-CEL-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Caenorhabditis elegans 16810 R-CEL-977333 https://reactome.org/PathwayBrowser/#/R-CEL-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Caenorhabditis elegans 16810 R-CFA-1234164 https://reactome.org/PathwayBrowser/#/R-CFA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Canis familiaris 16810 R-CFA-1234165 https://reactome.org/PathwayBrowser/#/R-CFA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 16810 R-CFA-1234173 https://reactome.org/PathwayBrowser/#/R-CFA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 16810 R-CFA-1234177 https://reactome.org/PathwayBrowser/#/R-CFA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 16810 R-CFA-1234181 https://reactome.org/PathwayBrowser/#/R-CFA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 16810 R-CFA-1650808 https://reactome.org/PathwayBrowser/#/R-CFA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Canis familiaris 16810 R-CFA-1980233 https://reactome.org/PathwayBrowser/#/R-CFA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Canis familiaris 16810 R-CFA-1981104 https://reactome.org/PathwayBrowser/#/R-CFA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Canis familiaris 16810 R-CFA-198440 https://reactome.org/PathwayBrowser/#/R-CFA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Canis familiaris 16810 R-CFA-2172678 https://reactome.org/PathwayBrowser/#/R-CFA-2172678 PHF8 demethylates histone H4K20me1 IEA Canis familiaris 16810 R-CFA-3222593 https://reactome.org/PathwayBrowser/#/R-CFA-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Canis familiaris 16810 R-CFA-372480 https://reactome.org/PathwayBrowser/#/R-CFA-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Canis familiaris 16810 R-CFA-376851 https://reactome.org/PathwayBrowser/#/R-CFA-376851 SLC25A11 exchanges 2-OG and MAL IEA Canis familiaris 16810 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 16810 R-CFA-389540 https://reactome.org/PathwayBrowser/#/R-CFA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 16810 R-CFA-389550 https://reactome.org/PathwayBrowser/#/R-CFA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 16810 R-CFA-389639 https://reactome.org/PathwayBrowser/#/R-CFA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Canis familiaris 16810 R-CFA-450984 https://reactome.org/PathwayBrowser/#/R-CFA-450984 IDH2 dimer decarboxylates isocitrate IEA Canis familiaris 16810 R-CFA-4722133 https://reactome.org/PathwayBrowser/#/R-CFA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Canis familiaris 16810 R-CFA-4724279 https://reactome.org/PathwayBrowser/#/R-CFA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Canis familiaris 16810 R-CFA-4724284 https://reactome.org/PathwayBrowser/#/R-CFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Canis familiaris 16810 R-CFA-4754176 https://reactome.org/PathwayBrowser/#/R-CFA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Canis familiaris 16810 R-CFA-4754181 https://reactome.org/PathwayBrowser/#/R-CFA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Canis familiaris 16810 R-CFA-4754187 https://reactome.org/PathwayBrowser/#/R-CFA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Canis familiaris 16810 R-CFA-507749 https://reactome.org/PathwayBrowser/#/R-CFA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Canis familiaris 16810 R-CFA-507775 https://reactome.org/PathwayBrowser/#/R-CFA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Canis familiaris 16810 R-CFA-508179 https://reactome.org/PathwayBrowser/#/R-CFA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Canis familiaris 16810 R-CFA-508189 https://reactome.org/PathwayBrowser/#/R-CFA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Canis familiaris 16810 R-CFA-508561 https://reactome.org/PathwayBrowser/#/R-CFA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Canis familiaris 16810 R-CFA-517444 https://reactome.org/PathwayBrowser/#/R-CFA-517444 TAT aminates HPP IEA Canis familiaris 16810 R-CFA-5423117 https://reactome.org/PathwayBrowser/#/R-CFA-5423117 PHF8 demethylates MeK21-histone H4 IEA Canis familiaris 16810 R-CFA-561041 https://reactome.org/PathwayBrowser/#/R-CFA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Canis familiaris 16810 R-CFA-561059 https://reactome.org/PathwayBrowser/#/R-CFA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Canis familiaris 16810 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 16810 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 16810 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 16810 R-CFA-5661114 https://reactome.org/PathwayBrowser/#/R-CFA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Canis familiaris 16810 R-CFA-5661115 https://reactome.org/PathwayBrowser/#/R-CFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Canis familiaris 16810 R-CFA-5661116 https://reactome.org/PathwayBrowser/#/R-CFA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Canis familiaris 16810 R-CFA-5661120 https://reactome.org/PathwayBrowser/#/R-CFA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Canis familiaris 16810 R-CFA-5661121 https://reactome.org/PathwayBrowser/#/R-CFA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Canis familiaris 16810 R-CFA-5661122 https://reactome.org/PathwayBrowser/#/R-CFA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Canis familiaris 16810 R-CFA-5661124 https://reactome.org/PathwayBrowser/#/R-CFA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Canis familiaris 16810 R-CFA-5661125 https://reactome.org/PathwayBrowser/#/R-CFA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Canis familiaris 16810 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 16810 R-CFA-70523 https://reactome.org/PathwayBrowser/#/R-CFA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Canis familiaris 16810 R-CFA-70524 https://reactome.org/PathwayBrowser/#/R-CFA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Canis familiaris 16810 R-CFA-70581 https://reactome.org/PathwayBrowser/#/R-CFA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Canis familiaris 16810 R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Canis familiaris 16810 R-CFA-70592 https://reactome.org/PathwayBrowser/#/R-CFA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Canis familiaris 16810 R-CFA-70596 https://reactome.org/PathwayBrowser/#/R-CFA-70596 GOT2 dimer deaminates L-Asp IEA Canis familiaris 16810 R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Canis familiaris 16810 R-CFA-70613 https://reactome.org/PathwayBrowser/#/R-CFA-70613 GOT2 transaminates OA and L-Glu IEA Canis familiaris 16810 R-CFA-70654 https://reactome.org/PathwayBrowser/#/R-CFA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Canis familiaris 16810 R-CFA-70666 https://reactome.org/PathwayBrowser/#/R-CFA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Canis familiaris 16810 R-CFA-70723 https://reactome.org/PathwayBrowser/#/R-CFA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Canis familiaris 16810 R-CFA-70724 https://reactome.org/PathwayBrowser/#/R-CFA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Canis familiaris 16810 R-CFA-70938 https://reactome.org/PathwayBrowser/#/R-CFA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Canis familiaris 16810 R-CFA-70952 https://reactome.org/PathwayBrowser/#/R-CFA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Canis familiaris 16810 R-CFA-70967 https://reactome.org/PathwayBrowser/#/R-CFA-70967 IDH3 complex decarboxylates isocitrate IEA Canis familiaris 16810 R-CFA-71155 https://reactome.org/PathwayBrowser/#/R-CFA-71155 TAT deaminates tyrosine IEA Canis familiaris 16810 R-CFA-71241 https://reactome.org/PathwayBrowser/#/R-CFA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Canis familiaris 16810 R-CFA-71261 https://reactome.org/PathwayBrowser/#/R-CFA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Canis familiaris 16810 R-CFA-71401 https://reactome.org/PathwayBrowser/#/R-CFA-71401 OGDH dimer decarboxylates 2-OG IEA Canis familiaris 16810 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 16810 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 16810 R-CFA-880002 https://reactome.org/PathwayBrowser/#/R-CFA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Canis familiaris 16810 R-CFA-880007 https://reactome.org/PathwayBrowser/#/R-CFA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Canis familiaris 16810 R-CFA-880033 https://reactome.org/PathwayBrowser/#/R-CFA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Canis familiaris 16810 R-CFA-880050 https://reactome.org/PathwayBrowser/#/R-CFA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Canis familiaris 16810 R-CFA-8857692 https://reactome.org/PathwayBrowser/#/R-CFA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Canis familiaris 16810 R-CFA-893583 https://reactome.org/PathwayBrowser/#/R-CFA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Canis familiaris 16810 R-CFA-916855 https://reactome.org/PathwayBrowser/#/R-CFA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Canis familiaris 16810 R-CFA-9629578 https://reactome.org/PathwayBrowser/#/R-CFA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Canis familiaris 16810 R-CFA-9629591 https://reactome.org/PathwayBrowser/#/R-CFA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Canis familiaris 16810 R-CFA-9629869 https://reactome.org/PathwayBrowser/#/R-CFA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Canis familiaris 16810 R-CFA-9629888 https://reactome.org/PathwayBrowser/#/R-CFA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Canis familiaris 16810 R-CFA-9629946 https://reactome.org/PathwayBrowser/#/R-CFA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Canis familiaris 16810 R-CFA-9630022 https://reactome.org/PathwayBrowser/#/R-CFA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Canis familiaris 16810 R-CFA-9630769 https://reactome.org/PathwayBrowser/#/R-CFA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Canis familiaris 16810 R-CFA-9630967 https://reactome.org/PathwayBrowser/#/R-CFA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Canis familiaris 16810 R-CFA-9630993 https://reactome.org/PathwayBrowser/#/R-CFA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Canis familiaris 16810 R-CFA-964773 https://reactome.org/PathwayBrowser/#/R-CFA-964773 OXGR1 binds 2OG IEA Canis familiaris 16810 R-CFA-977333 https://reactome.org/PathwayBrowser/#/R-CFA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Canis familiaris 16810 R-DDI-2172678 https://reactome.org/PathwayBrowser/#/R-DDI-2172678 PHF8 demethylates histone H4K20me1 IEA Dictyostelium discoideum 16810 R-DDI-3222593 https://reactome.org/PathwayBrowser/#/R-DDI-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Dictyostelium discoideum 16810 R-DDI-372480 https://reactome.org/PathwayBrowser/#/R-DDI-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Dictyostelium discoideum 16810 R-DDI-389540 https://reactome.org/PathwayBrowser/#/R-DDI-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 16810 R-DDI-389550 https://reactome.org/PathwayBrowser/#/R-DDI-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 16810 R-DDI-389639 https://reactome.org/PathwayBrowser/#/R-DDI-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Dictyostelium discoideum 16810 R-DDI-4754181 https://reactome.org/PathwayBrowser/#/R-DDI-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Dictyostelium discoideum 16810 R-DDI-4754187 https://reactome.org/PathwayBrowser/#/R-DDI-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Dictyostelium discoideum 16810 R-DDI-507749 https://reactome.org/PathwayBrowser/#/R-DDI-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Dictyostelium discoideum 16810 R-DDI-507775 https://reactome.org/PathwayBrowser/#/R-DDI-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Dictyostelium discoideum 16810 R-DDI-508179 https://reactome.org/PathwayBrowser/#/R-DDI-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Dictyostelium discoideum 16810 R-DDI-508189 https://reactome.org/PathwayBrowser/#/R-DDI-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Dictyostelium discoideum 16810 R-DDI-508561 https://reactome.org/PathwayBrowser/#/R-DDI-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Dictyostelium discoideum 16810 R-DDI-517444 https://reactome.org/PathwayBrowser/#/R-DDI-517444 TAT aminates HPP IEA Dictyostelium discoideum 16810 R-DDI-5661116 https://reactome.org/PathwayBrowser/#/R-DDI-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Dictyostelium discoideum 16810 R-DDI-5661121 https://reactome.org/PathwayBrowser/#/R-DDI-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Dictyostelium discoideum 16810 R-DDI-70523 https://reactome.org/PathwayBrowser/#/R-DDI-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Dictyostelium discoideum 16810 R-DDI-70524 https://reactome.org/PathwayBrowser/#/R-DDI-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Dictyostelium discoideum 16810 R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Dictyostelium discoideum 16810 R-DDI-70596 https://reactome.org/PathwayBrowser/#/R-DDI-70596 GOT2 dimer deaminates L-Asp IEA Dictyostelium discoideum 16810 R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Dictyostelium discoideum 16810 R-DDI-70613 https://reactome.org/PathwayBrowser/#/R-DDI-70613 GOT2 transaminates OA and L-Glu IEA Dictyostelium discoideum 16810 R-DDI-70654 https://reactome.org/PathwayBrowser/#/R-DDI-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Dictyostelium discoideum 16810 R-DDI-70666 https://reactome.org/PathwayBrowser/#/R-DDI-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Dictyostelium discoideum 16810 R-DDI-70723 https://reactome.org/PathwayBrowser/#/R-DDI-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Dictyostelium discoideum 16810 R-DDI-70724 https://reactome.org/PathwayBrowser/#/R-DDI-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Dictyostelium discoideum 16810 R-DDI-70938 https://reactome.org/PathwayBrowser/#/R-DDI-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Dictyostelium discoideum 16810 R-DDI-70952 https://reactome.org/PathwayBrowser/#/R-DDI-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Dictyostelium discoideum 16810 R-DDI-70967 https://reactome.org/PathwayBrowser/#/R-DDI-70967 IDH3 complex decarboxylates isocitrate IEA Dictyostelium discoideum 16810 R-DDI-71155 https://reactome.org/PathwayBrowser/#/R-DDI-71155 TAT deaminates tyrosine IEA Dictyostelium discoideum 16810 R-DDI-71401 https://reactome.org/PathwayBrowser/#/R-DDI-71401 OGDH dimer decarboxylates 2-OG IEA Dictyostelium discoideum 16810 R-DDI-880002 https://reactome.org/PathwayBrowser/#/R-DDI-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Dictyostelium discoideum 16810 R-DDI-880007 https://reactome.org/PathwayBrowser/#/R-DDI-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Dictyostelium discoideum 16810 R-DDI-880033 https://reactome.org/PathwayBrowser/#/R-DDI-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Dictyostelium discoideum 16810 R-DDI-880050 https://reactome.org/PathwayBrowser/#/R-DDI-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Dictyostelium discoideum 16810 R-DDI-893583 https://reactome.org/PathwayBrowser/#/R-DDI-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Dictyostelium discoideum 16810 R-DDI-916855 https://reactome.org/PathwayBrowser/#/R-DDI-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Dictyostelium discoideum 16810 R-DDI-9629578 https://reactome.org/PathwayBrowser/#/R-DDI-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Dictyostelium discoideum 16810 R-DDI-9629591 https://reactome.org/PathwayBrowser/#/R-DDI-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Dictyostelium discoideum 16810 R-DDI-9629869 https://reactome.org/PathwayBrowser/#/R-DDI-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Dictyostelium discoideum 16810 R-DDI-9630993 https://reactome.org/PathwayBrowser/#/R-DDI-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Dictyostelium discoideum 16810 R-DDI-977333 https://reactome.org/PathwayBrowser/#/R-DDI-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Dictyostelium discoideum 16810 R-DME-1234165 https://reactome.org/PathwayBrowser/#/R-DME-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 16810 R-DME-1234173 https://reactome.org/PathwayBrowser/#/R-DME-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 16810 R-DME-1234177 https://reactome.org/PathwayBrowser/#/R-DME-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 16810 R-DME-1234181 https://reactome.org/PathwayBrowser/#/R-DME-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 16810 R-DME-1981104 https://reactome.org/PathwayBrowser/#/R-DME-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Drosophila melanogaster 16810 R-DME-198440 https://reactome.org/PathwayBrowser/#/R-DME-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Drosophila melanogaster 16810 R-DME-2172678 https://reactome.org/PathwayBrowser/#/R-DME-2172678 PHF8 demethylates histone H4K20me1 IEA Drosophila melanogaster 16810 R-DME-3222593 https://reactome.org/PathwayBrowser/#/R-DME-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Drosophila melanogaster 16810 R-DME-372480 https://reactome.org/PathwayBrowser/#/R-DME-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Drosophila melanogaster 16810 R-DME-376851 https://reactome.org/PathwayBrowser/#/R-DME-376851 SLC25A11 exchanges 2-OG and MAL IEA Drosophila melanogaster 16810 R-DME-389540 https://reactome.org/PathwayBrowser/#/R-DME-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 16810 R-DME-389550 https://reactome.org/PathwayBrowser/#/R-DME-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 16810 R-DME-507749 https://reactome.org/PathwayBrowser/#/R-DME-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Drosophila melanogaster 16810 R-DME-507775 https://reactome.org/PathwayBrowser/#/R-DME-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Drosophila melanogaster 16810 R-DME-508179 https://reactome.org/PathwayBrowser/#/R-DME-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Drosophila melanogaster 16810 R-DME-508189 https://reactome.org/PathwayBrowser/#/R-DME-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Drosophila melanogaster 16810 R-DME-517444 https://reactome.org/PathwayBrowser/#/R-DME-517444 TAT aminates HPP IEA Drosophila melanogaster 16810 R-DME-561041 https://reactome.org/PathwayBrowser/#/R-DME-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Drosophila melanogaster 16810 R-DME-561059 https://reactome.org/PathwayBrowser/#/R-DME-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Drosophila melanogaster 16810 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 16810 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 16810 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 16810 R-DME-5661124 https://reactome.org/PathwayBrowser/#/R-DME-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Drosophila melanogaster 16810 R-DME-5661125 https://reactome.org/PathwayBrowser/#/R-DME-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Drosophila melanogaster 16810 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 16810 R-DME-70523 https://reactome.org/PathwayBrowser/#/R-DME-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Drosophila melanogaster 16810 R-DME-70524 https://reactome.org/PathwayBrowser/#/R-DME-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Drosophila melanogaster 16810 R-DME-70581 https://reactome.org/PathwayBrowser/#/R-DME-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Drosophila melanogaster 16810 R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Drosophila melanogaster 16810 R-DME-70592 https://reactome.org/PathwayBrowser/#/R-DME-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Drosophila melanogaster 16810 R-DME-70596 https://reactome.org/PathwayBrowser/#/R-DME-70596 GOT2 dimer deaminates L-Asp IEA Drosophila melanogaster 16810 R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Drosophila melanogaster 16810 R-DME-70613 https://reactome.org/PathwayBrowser/#/R-DME-70613 GOT2 transaminates OA and L-Glu IEA Drosophila melanogaster 16810 R-DME-70654 https://reactome.org/PathwayBrowser/#/R-DME-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Drosophila melanogaster 16810 R-DME-70666 https://reactome.org/PathwayBrowser/#/R-DME-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Drosophila melanogaster 16810 R-DME-70723 https://reactome.org/PathwayBrowser/#/R-DME-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Drosophila melanogaster 16810 R-DME-70724 https://reactome.org/PathwayBrowser/#/R-DME-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Drosophila melanogaster 16810 R-DME-70938 https://reactome.org/PathwayBrowser/#/R-DME-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Drosophila melanogaster 16810 R-DME-70967 https://reactome.org/PathwayBrowser/#/R-DME-70967 IDH3 complex decarboxylates isocitrate IEA Drosophila melanogaster 16810 R-DME-71155 https://reactome.org/PathwayBrowser/#/R-DME-71155 TAT deaminates tyrosine IEA Drosophila melanogaster 16810 R-DME-71241 https://reactome.org/PathwayBrowser/#/R-DME-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Drosophila melanogaster 16810 R-DME-71261 https://reactome.org/PathwayBrowser/#/R-DME-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Drosophila melanogaster 16810 R-DME-71401 https://reactome.org/PathwayBrowser/#/R-DME-71401 OGDH dimer decarboxylates 2-OG IEA Drosophila melanogaster 16810 R-DME-880002 https://reactome.org/PathwayBrowser/#/R-DME-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Drosophila melanogaster 16810 R-DME-880007 https://reactome.org/PathwayBrowser/#/R-DME-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Drosophila melanogaster 16810 R-DME-880033 https://reactome.org/PathwayBrowser/#/R-DME-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Drosophila melanogaster 16810 R-DME-880050 https://reactome.org/PathwayBrowser/#/R-DME-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Drosophila melanogaster 16810 R-DME-916855 https://reactome.org/PathwayBrowser/#/R-DME-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Drosophila melanogaster 16810 R-DME-9629578 https://reactome.org/PathwayBrowser/#/R-DME-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Drosophila melanogaster 16810 R-DME-9629591 https://reactome.org/PathwayBrowser/#/R-DME-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Drosophila melanogaster 16810 R-DME-9629869 https://reactome.org/PathwayBrowser/#/R-DME-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Drosophila melanogaster 16810 R-DME-9629888 https://reactome.org/PathwayBrowser/#/R-DME-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Drosophila melanogaster 16810 R-DME-9629946 https://reactome.org/PathwayBrowser/#/R-DME-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Drosophila melanogaster 16810 R-DME-9630022 https://reactome.org/PathwayBrowser/#/R-DME-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Drosophila melanogaster 16810 R-DME-9630769 https://reactome.org/PathwayBrowser/#/R-DME-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Drosophila melanogaster 16810 R-DME-9630993 https://reactome.org/PathwayBrowser/#/R-DME-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Drosophila melanogaster 16810 R-DME-977333 https://reactome.org/PathwayBrowser/#/R-DME-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Drosophila melanogaster 16810 R-DRE-1234164 https://reactome.org/PathwayBrowser/#/R-DRE-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Danio rerio 16810 R-DRE-1234165 https://reactome.org/PathwayBrowser/#/R-DRE-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Danio rerio 16810 R-DRE-1234181 https://reactome.org/PathwayBrowser/#/R-DRE-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Danio rerio 16810 R-DRE-1650808 https://reactome.org/PathwayBrowser/#/R-DRE-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Danio rerio 16810 R-DRE-1981104 https://reactome.org/PathwayBrowser/#/R-DRE-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Danio rerio 16810 R-DRE-198440 https://reactome.org/PathwayBrowser/#/R-DRE-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Danio rerio 16810 R-DRE-2172678 https://reactome.org/PathwayBrowser/#/R-DRE-2172678 PHF8 demethylates histone H4K20me1 IEA Danio rerio 16810 R-DRE-372480 https://reactome.org/PathwayBrowser/#/R-DRE-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Danio rerio 16810 R-DRE-376851 https://reactome.org/PathwayBrowser/#/R-DRE-376851 SLC25A11 exchanges 2-OG and MAL IEA Danio rerio 16810 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 16810 R-DRE-389540 https://reactome.org/PathwayBrowser/#/R-DRE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 16810 R-DRE-389550 https://reactome.org/PathwayBrowser/#/R-DRE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 16810 R-DRE-389639 https://reactome.org/PathwayBrowser/#/R-DRE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Danio rerio 16810 R-DRE-450984 https://reactome.org/PathwayBrowser/#/R-DRE-450984 IDH2 dimer decarboxylates isocitrate IEA Danio rerio 16810 R-DRE-508179 https://reactome.org/PathwayBrowser/#/R-DRE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Danio rerio 16810 R-DRE-508189 https://reactome.org/PathwayBrowser/#/R-DRE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Danio rerio 16810 R-DRE-517444 https://reactome.org/PathwayBrowser/#/R-DRE-517444 TAT aminates HPP IEA Danio rerio 16810 R-DRE-5423117 https://reactome.org/PathwayBrowser/#/R-DRE-5423117 PHF8 demethylates MeK21-histone H4 IEA Danio rerio 16810 R-DRE-561041 https://reactome.org/PathwayBrowser/#/R-DRE-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Danio rerio 16810 R-DRE-561059 https://reactome.org/PathwayBrowser/#/R-DRE-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Danio rerio 16810 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 16810 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 16810 R-DRE-5661124 https://reactome.org/PathwayBrowser/#/R-DRE-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Danio rerio 16810 R-DRE-5661125 https://reactome.org/PathwayBrowser/#/R-DRE-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Danio rerio 16810 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 16810 R-DRE-70523 https://reactome.org/PathwayBrowser/#/R-DRE-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Danio rerio 16810 R-DRE-70524 https://reactome.org/PathwayBrowser/#/R-DRE-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Danio rerio 16810 R-DRE-70581 https://reactome.org/PathwayBrowser/#/R-DRE-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Danio rerio 16810 R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Danio rerio 16810 R-DRE-70592 https://reactome.org/PathwayBrowser/#/R-DRE-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Danio rerio 16810 R-DRE-70596 https://reactome.org/PathwayBrowser/#/R-DRE-70596 GOT2 dimer deaminates L-Asp IEA Danio rerio 16810 R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Danio rerio 16810 R-DRE-70613 https://reactome.org/PathwayBrowser/#/R-DRE-70613 GOT2 transaminates OA and L-Glu IEA Danio rerio 16810 R-DRE-70723 https://reactome.org/PathwayBrowser/#/R-DRE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Danio rerio 16810 R-DRE-70724 https://reactome.org/PathwayBrowser/#/R-DRE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Danio rerio 16810 R-DRE-70938 https://reactome.org/PathwayBrowser/#/R-DRE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Danio rerio 16810 R-DRE-71155 https://reactome.org/PathwayBrowser/#/R-DRE-71155 TAT deaminates tyrosine IEA Danio rerio 16810 R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio 16810 R-DRE-71401 https://reactome.org/PathwayBrowser/#/R-DRE-71401 OGDH dimer decarboxylates 2-OG IEA Danio rerio 16810 R-DRE-880002 https://reactome.org/PathwayBrowser/#/R-DRE-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Danio rerio 16810 R-DRE-880007 https://reactome.org/PathwayBrowser/#/R-DRE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Danio rerio 16810 R-DRE-880033 https://reactome.org/PathwayBrowser/#/R-DRE-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Danio rerio 16810 R-DRE-8857692 https://reactome.org/PathwayBrowser/#/R-DRE-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Danio rerio 16810 R-DRE-916855 https://reactome.org/PathwayBrowser/#/R-DRE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Danio rerio 16810 R-DRE-9629591 https://reactome.org/PathwayBrowser/#/R-DRE-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Danio rerio 16810 R-DRE-9629869 https://reactome.org/PathwayBrowser/#/R-DRE-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Danio rerio 16810 R-DRE-9629946 https://reactome.org/PathwayBrowser/#/R-DRE-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Danio rerio 16810 R-DRE-9630993 https://reactome.org/PathwayBrowser/#/R-DRE-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Danio rerio 16810 R-DRE-964773 https://reactome.org/PathwayBrowser/#/R-DRE-964773 OXGR1 binds 2OG IEA Danio rerio 16810 R-DRE-977333 https://reactome.org/PathwayBrowser/#/R-DRE-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Danio rerio 16810 R-GGA-1234164 https://reactome.org/PathwayBrowser/#/R-GGA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Gallus gallus 16810 R-GGA-1234165 https://reactome.org/PathwayBrowser/#/R-GGA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 16810 R-GGA-1234173 https://reactome.org/PathwayBrowser/#/R-GGA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 16810 R-GGA-1234177 https://reactome.org/PathwayBrowser/#/R-GGA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 16810 R-GGA-1234181 https://reactome.org/PathwayBrowser/#/R-GGA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 16810 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus 16810 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus 16810 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus 16810 R-GGA-198440 https://reactome.org/PathwayBrowser/#/R-GGA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Gallus gallus 16810 R-GGA-2172678 https://reactome.org/PathwayBrowser/#/R-GGA-2172678 PHF8 demethylates histone H4K20me1 IEA Gallus gallus 16810 R-GGA-353356 https://reactome.org/PathwayBrowser/#/R-GGA-353356 Reversal of Alkylation Damage By DNA Dioxygenases TAS Gallus gallus 16810 R-GGA-372480 https://reactome.org/PathwayBrowser/#/R-GGA-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Gallus gallus 16810 R-GGA-372559 https://reactome.org/PathwayBrowser/#/R-GGA-372559 aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate TAS Gallus gallus 16810 R-GGA-372564 https://reactome.org/PathwayBrowser/#/R-GGA-372564 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) TAS Gallus gallus 16810 R-GGA-372717 https://reactome.org/PathwayBrowser/#/R-GGA-372717 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) TAS Gallus gallus 16810 R-GGA-372719 https://reactome.org/PathwayBrowser/#/R-GGA-372719 aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate TAS Gallus gallus 16810 R-GGA-372742 https://reactome.org/PathwayBrowser/#/R-GGA-372742 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Gallus gallus 16810 R-GGA-373024 https://reactome.org/PathwayBrowser/#/R-GGA-373024 isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ IEA Gallus gallus 16810 R-GGA-373042 https://reactome.org/PathwayBrowser/#/R-GGA-373042 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ IEA Gallus gallus 16810 R-GGA-376851 https://reactome.org/PathwayBrowser/#/R-GGA-376851 SLC25A11 exchanges 2-OG and MAL IEA Gallus gallus 16810 R-GGA-376887 https://reactome.org/PathwayBrowser/#/R-GGA-376887 2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix] IEA Gallus gallus 16810 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 16810 R-GGA-389540 https://reactome.org/PathwayBrowser/#/R-GGA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 16810 R-GGA-389550 https://reactome.org/PathwayBrowser/#/R-GGA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 16810 R-GGA-389639 https://reactome.org/PathwayBrowser/#/R-GGA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Gallus gallus 16810 R-GGA-450984 https://reactome.org/PathwayBrowser/#/R-GGA-450984 IDH2 dimer decarboxylates isocitrate IEA Gallus gallus 16810 R-GGA-507749 https://reactome.org/PathwayBrowser/#/R-GGA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Gallus gallus 16810 R-GGA-507775 https://reactome.org/PathwayBrowser/#/R-GGA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Gallus gallus 16810 R-GGA-508189 https://reactome.org/PathwayBrowser/#/R-GGA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Gallus gallus 16810 R-GGA-508561 https://reactome.org/PathwayBrowser/#/R-GGA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Gallus gallus 16810 R-GGA-517444 https://reactome.org/PathwayBrowser/#/R-GGA-517444 TAT aminates HPP IEA Gallus gallus 16810 R-GGA-561041 https://reactome.org/PathwayBrowser/#/R-GGA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Gallus gallus 16810 R-GGA-561059 https://reactome.org/PathwayBrowser/#/R-GGA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Gallus gallus 16810 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 16810 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 16810 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 16810 R-GGA-5661124 https://reactome.org/PathwayBrowser/#/R-GGA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Gallus gallus 16810 R-GGA-5661125 https://reactome.org/PathwayBrowser/#/R-GGA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Gallus gallus 16810 R-GGA-70581 https://reactome.org/PathwayBrowser/#/R-GGA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Gallus gallus 16810 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Gallus gallus 16810 R-GGA-70592 https://reactome.org/PathwayBrowser/#/R-GGA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Gallus gallus 16810 R-GGA-70596 https://reactome.org/PathwayBrowser/#/R-GGA-70596 GOT2 dimer deaminates L-Asp IEA Gallus gallus 16810 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Gallus gallus 16810 R-GGA-70613 https://reactome.org/PathwayBrowser/#/R-GGA-70613 GOT2 transaminates OA and L-Glu IEA Gallus gallus 16810 R-GGA-70654 https://reactome.org/PathwayBrowser/#/R-GGA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Gallus gallus 16810 R-GGA-70666 https://reactome.org/PathwayBrowser/#/R-GGA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Gallus gallus 16810 R-GGA-70723 https://reactome.org/PathwayBrowser/#/R-GGA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Gallus gallus 16810 R-GGA-70938 https://reactome.org/PathwayBrowser/#/R-GGA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Gallus gallus 16810 R-GGA-70952 https://reactome.org/PathwayBrowser/#/R-GGA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Gallus gallus 16810 R-GGA-71155 https://reactome.org/PathwayBrowser/#/R-GGA-71155 TAT deaminates tyrosine IEA Gallus gallus 16810 R-GGA-71241 https://reactome.org/PathwayBrowser/#/R-GGA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Gallus gallus 16810 R-GGA-71261 https://reactome.org/PathwayBrowser/#/R-GGA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Gallus gallus 16810 R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus 16810 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 16810 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 16810 R-GGA-880002 https://reactome.org/PathwayBrowser/#/R-GGA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Gallus gallus 16810 R-GGA-880007 https://reactome.org/PathwayBrowser/#/R-GGA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus 16810 R-GGA-880033 https://reactome.org/PathwayBrowser/#/R-GGA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Gallus gallus 16810 R-GGA-880050 https://reactome.org/PathwayBrowser/#/R-GGA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus 16810 R-GGA-8857692 https://reactome.org/PathwayBrowser/#/R-GGA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Gallus gallus 16810 R-GGA-893583 https://reactome.org/PathwayBrowser/#/R-GGA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Gallus gallus 16810 R-GGA-916855 https://reactome.org/PathwayBrowser/#/R-GGA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Gallus gallus 16810 R-GGA-9629578 https://reactome.org/PathwayBrowser/#/R-GGA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Gallus gallus 16810 R-GGA-9629591 https://reactome.org/PathwayBrowser/#/R-GGA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Gallus gallus 16810 R-GGA-9629869 https://reactome.org/PathwayBrowser/#/R-GGA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Gallus gallus 16810 R-GGA-9629946 https://reactome.org/PathwayBrowser/#/R-GGA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Gallus gallus 16810 R-GGA-9630022 https://reactome.org/PathwayBrowser/#/R-GGA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Gallus gallus 16810 R-GGA-9630769 https://reactome.org/PathwayBrowser/#/R-GGA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Gallus gallus 16810 R-GGA-9630967 https://reactome.org/PathwayBrowser/#/R-GGA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Gallus gallus 16810 R-GGA-9630993 https://reactome.org/PathwayBrowser/#/R-GGA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Gallus gallus 16810 R-GGA-964773 https://reactome.org/PathwayBrowser/#/R-GGA-964773 OXGR1 binds 2OG IEA Gallus gallus 16810 R-GGA-977333 https://reactome.org/PathwayBrowser/#/R-GGA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Gallus gallus 16810 R-HSA-112118 https://reactome.org/PathwayBrowser/#/R-HSA-112118 Oxidative demethylation of 1-meA damaged DNA by ALKBH2 TAS Homo sapiens 16810 R-HSA-112120 https://reactome.org/PathwayBrowser/#/R-HSA-112120 Oxidative demethylation of 3-meC damaged DNA by ALKBH2 TAS Homo sapiens 16810 R-HSA-112121 https://reactome.org/PathwayBrowser/#/R-HSA-112121 Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 TAS Homo sapiens 16810 R-HSA-112123 https://reactome.org/PathwayBrowser/#/R-HSA-112123 Oxidative demethylation of 1-meA damaged DNA By ALKBH3 TAS Homo sapiens 16810 R-HSA-112124 https://reactome.org/PathwayBrowser/#/R-HSA-112124 Oxidative demethylation of 3-meC damaged DNA By ALKBH3 TAS Homo sapiens 16810 R-HSA-112125 https://reactome.org/PathwayBrowser/#/R-HSA-112125 Oxidative dealkylation of 1-EtA damaged DNA by ABH3 TAS Homo sapiens 16810 R-HSA-1234164 https://reactome.org/PathwayBrowser/#/R-HSA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) TAS Homo sapiens 16810 R-HSA-1234165 https://reactome.org/PathwayBrowser/#/R-HSA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 16810 R-HSA-1234166 https://reactome.org/PathwayBrowser/#/R-HSA-1234166 Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 16810 R-HSA-1234173 https://reactome.org/PathwayBrowser/#/R-HSA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 16810 R-HSA-1234177 https://reactome.org/PathwayBrowser/#/R-HSA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 16810 R-HSA-1234179 https://reactome.org/PathwayBrowser/#/R-HSA-1234179 Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 16810 R-HSA-1234181 https://reactome.org/PathwayBrowser/#/R-HSA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 16810 R-HSA-1650808 https://reactome.org/PathwayBrowser/#/R-HSA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines TAS Homo sapiens 16810 R-HSA-1980233 https://reactome.org/PathwayBrowser/#/R-HSA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen TAS Homo sapiens 16810 R-HSA-1981104 https://reactome.org/PathwayBrowser/#/R-HSA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines TAS Homo sapiens 16810 R-HSA-198440 https://reactome.org/PathwayBrowser/#/R-HSA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane TAS Homo sapiens 16810 R-HSA-2172678 https://reactome.org/PathwayBrowser/#/R-HSA-2172678 PHF8 demethylates histone H4K20me1 TAS Homo sapiens 16810 R-HSA-3222593 https://reactome.org/PathwayBrowser/#/R-HSA-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter TAS Homo sapiens 16810 R-HSA-372480 https://reactome.org/PathwayBrowser/#/R-HSA-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] TAS Homo sapiens 16810 R-HSA-376851 https://reactome.org/PathwayBrowser/#/R-HSA-376851 SLC25A11 exchanges 2-OG and MAL TAS Homo sapiens 16810 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 16810 R-HSA-389540 https://reactome.org/PathwayBrowser/#/R-HSA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 16810 R-HSA-389550 https://reactome.org/PathwayBrowser/#/R-HSA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 16810 R-HSA-389639 https://reactome.org/PathwayBrowser/#/R-HSA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 TAS Homo sapiens 16810 R-HSA-390347 https://reactome.org/PathwayBrowser/#/R-HSA-390347 Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane TAS Homo sapiens 16810 R-HSA-450984 https://reactome.org/PathwayBrowser/#/R-HSA-450984 IDH2 dimer decarboxylates isocitrate TAS Homo sapiens 16810 R-HSA-4722133 https://reactome.org/PathwayBrowser/#/R-HSA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 TAS Homo sapiens 16810 R-HSA-4724279 https://reactome.org/PathwayBrowser/#/R-HSA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 TAS Homo sapiens 16810 R-HSA-4724284 https://reactome.org/PathwayBrowser/#/R-HSA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 TAS Homo sapiens 16810 R-HSA-4754176 https://reactome.org/PathwayBrowser/#/R-HSA-4754176 JMJD6 demethylates MeR3-histone H3 TAS Homo sapiens 16810 R-HSA-4754181 https://reactome.org/PathwayBrowser/#/R-HSA-4754181 KDM5A-D demethylate Me2K5-histone H3 TAS Homo sapiens 16810 R-HSA-4754187 https://reactome.org/PathwayBrowser/#/R-HSA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 TAS Homo sapiens 16810 R-HSA-507749 https://reactome.org/PathwayBrowser/#/R-HSA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala TAS Homo sapiens 16810 R-HSA-507775 https://reactome.org/PathwayBrowser/#/R-HSA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR TAS Homo sapiens 16810 R-HSA-508179 https://reactome.org/PathwayBrowser/#/R-HSA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] TAS Homo sapiens 16810 R-HSA-508189 https://reactome.org/PathwayBrowser/#/R-HSA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] TAS Homo sapiens 16810 R-HSA-508561 https://reactome.org/PathwayBrowser/#/R-HSA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate TAS Homo sapiens 16810 R-HSA-517444 https://reactome.org/PathwayBrowser/#/R-HSA-517444 TAT aminates HPP TAS Homo sapiens 16810 R-HSA-5220952 https://reactome.org/PathwayBrowser/#/R-HSA-5220952 TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine IEA Homo sapiens 16810 R-HSA-5220990 https://reactome.org/PathwayBrowser/#/R-HSA-5220990 TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine IEA Homo sapiens 16810 R-HSA-5221014 https://reactome.org/PathwayBrowser/#/R-HSA-5221014 TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine IEA Homo sapiens 16810 R-HSA-5423117 https://reactome.org/PathwayBrowser/#/R-HSA-5423117 PHF8 demethylates MeK21-histone H4 TAS Homo sapiens 16810 R-HSA-561041 https://reactome.org/PathwayBrowser/#/R-HSA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids TAS Homo sapiens 16810 R-HSA-561059 https://reactome.org/PathwayBrowser/#/R-HSA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates TAS Homo sapiens 16810 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 16810 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 16810 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 16810 R-HSA-5661114 https://reactome.org/PathwayBrowser/#/R-HSA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 TAS Homo sapiens 16810 R-HSA-5661115 https://reactome.org/PathwayBrowser/#/R-HSA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 TAS Homo sapiens 16810 R-HSA-5661116 https://reactome.org/PathwayBrowser/#/R-HSA-5661116 KDM5A-D demethylate Me3K5-histone H3 TAS Homo sapiens 16810 R-HSA-5661120 https://reactome.org/PathwayBrowser/#/R-HSA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 TAS Homo sapiens 16810 R-HSA-5661121 https://reactome.org/PathwayBrowser/#/R-HSA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 TAS Homo sapiens 16810 R-HSA-5661122 https://reactome.org/PathwayBrowser/#/R-HSA-5661122 JMJD6 demethylates Me2R3-histone H3 TAS Homo sapiens 16810 R-HSA-5661124 https://reactome.org/PathwayBrowser/#/R-HSA-5661124 JMJD6 demethylates MeR4-HIST1H4 TAS Homo sapiens 16810 R-HSA-5661125 https://reactome.org/PathwayBrowser/#/R-HSA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 TAS Homo sapiens 16810 R-HSA-6783455 https://reactome.org/PathwayBrowser/#/R-HSA-6783455 TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 16810 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 16810 R-HSA-70523 https://reactome.org/PathwayBrowser/#/R-HSA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR TAS Homo sapiens 16810 R-HSA-70524 https://reactome.org/PathwayBrowser/#/R-HSA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala TAS Homo sapiens 16810 R-HSA-70581 https://reactome.org/PathwayBrowser/#/R-HSA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] TAS Homo sapiens 16810 R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] TAS Homo sapiens 16810 R-HSA-70592 https://reactome.org/PathwayBrowser/#/R-HSA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp TAS Homo sapiens 16810 R-HSA-70596 https://reactome.org/PathwayBrowser/#/R-HSA-70596 GOT2 dimer deaminates L-Asp TAS Homo sapiens 16810 R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] TAS Homo sapiens 16810 R-HSA-70613 https://reactome.org/PathwayBrowser/#/R-HSA-70613 GOT2 transaminates OA and L-Glu TAS Homo sapiens 16810 R-HSA-70654 https://reactome.org/PathwayBrowser/#/R-HSA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] TAS Homo sapiens 16810 R-HSA-70666 https://reactome.org/PathwayBrowser/#/R-HSA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] TAS Homo sapiens 16810 R-HSA-70723 https://reactome.org/PathwayBrowser/#/R-HSA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] TAS Homo sapiens 16810 R-HSA-70724 https://reactome.org/PathwayBrowser/#/R-HSA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] TAS Homo sapiens 16810 R-HSA-70938 https://reactome.org/PathwayBrowser/#/R-HSA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O TAS Homo sapiens 16810 R-HSA-70952 https://reactome.org/PathwayBrowser/#/R-HSA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate TAS Homo sapiens 16810 R-HSA-70967 https://reactome.org/PathwayBrowser/#/R-HSA-70967 IDH3 complex decarboxylates isocitrate TAS Homo sapiens 16810 R-HSA-71155 https://reactome.org/PathwayBrowser/#/R-HSA-71155 TAT deaminates tyrosine TAS Homo sapiens 16810 R-HSA-71241 https://reactome.org/PathwayBrowser/#/R-HSA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA TAS Homo sapiens 16810 R-HSA-71261 https://reactome.org/PathwayBrowser/#/R-HSA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA TAS Homo sapiens 16810 R-HSA-71401 https://reactome.org/PathwayBrowser/#/R-HSA-71401 OGDH dimer decarboxylates 2-OG TAS Homo sapiens 16810 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 16810 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 16810 R-HSA-880002 https://reactome.org/PathwayBrowser/#/R-HSA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate TAS Homo sapiens 16810 R-HSA-880007 https://reactome.org/PathwayBrowser/#/R-HSA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 TAS Homo sapiens 16810 R-HSA-880033 https://reactome.org/PathwayBrowser/#/R-HSA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde TAS Homo sapiens 16810 R-HSA-880050 https://reactome.org/PathwayBrowser/#/R-HSA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 TAS Homo sapiens 16810 R-HSA-880053 https://reactome.org/PathwayBrowser/#/R-HSA-880053 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] TAS Homo sapiens 16810 R-HSA-8857692 https://reactome.org/PathwayBrowser/#/R-HSA-8857692 RNA demethylases demethylate N6-methyladenosine RNA TAS Homo sapiens 16810 R-HSA-893583 https://reactome.org/PathwayBrowser/#/R-HSA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate TAS Homo sapiens 16810 R-HSA-9012597 https://reactome.org/PathwayBrowser/#/R-HSA-9012597 GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu IEA Homo sapiens 16810 R-HSA-916855 https://reactome.org/PathwayBrowser/#/R-HSA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA TAS Homo sapiens 16810 R-HSA-9629578 https://reactome.org/PathwayBrowser/#/R-HSA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 TAS Homo sapiens 16810 R-HSA-9629591 https://reactome.org/PathwayBrowser/#/R-HSA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 TAS Homo sapiens 16810 R-HSA-9629869 https://reactome.org/PathwayBrowser/#/R-HSA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 TAS Homo sapiens 16810 R-HSA-9629888 https://reactome.org/PathwayBrowser/#/R-HSA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 TAS Homo sapiens 16810 R-HSA-9629946 https://reactome.org/PathwayBrowser/#/R-HSA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 TAS Homo sapiens 16810 R-HSA-9630022 https://reactome.org/PathwayBrowser/#/R-HSA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 TAS Homo sapiens 16810 R-HSA-9630769 https://reactome.org/PathwayBrowser/#/R-HSA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 TAS Homo sapiens 16810 R-HSA-9630967 https://reactome.org/PathwayBrowser/#/R-HSA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A TAS Homo sapiens 16810 R-HSA-9630993 https://reactome.org/PathwayBrowser/#/R-HSA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 TAS Homo sapiens 16810 R-HSA-9631355 https://reactome.org/PathwayBrowser/#/R-HSA-9631355 ASPH:Fe2+ hydroxylates an aspartate residue of F9 IEA Homo sapiens 16810 R-HSA-964773 https://reactome.org/PathwayBrowser/#/R-HSA-964773 OXGR1 binds 2OG TAS Homo sapiens 16810 R-HSA-977333 https://reactome.org/PathwayBrowser/#/R-HSA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA TAS Homo sapiens 16810 R-HSA-9817458 https://reactome.org/PathwayBrowser/#/R-HSA-9817458 TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 IEA Homo sapiens 16810 R-HSA-9822461 https://reactome.org/PathwayBrowser/#/R-HSA-9822461 KDM5B demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 16810 R-HSA-9822467 https://reactome.org/PathwayBrowser/#/R-HSA-9822467 KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 16810 R-HSA-9822914 https://reactome.org/PathwayBrowser/#/R-HSA-9822914 KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 16810 R-HSA-9822985 https://reactome.org/PathwayBrowser/#/R-HSA-9822985 KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 16810 R-MMU-1234164 https://reactome.org/PathwayBrowser/#/R-MMU-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Mus musculus 16810 R-MMU-1234165 https://reactome.org/PathwayBrowser/#/R-MMU-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Mus musculus 16810 R-MMU-1234173 https://reactome.org/PathwayBrowser/#/R-MMU-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Mus musculus 16810 R-MMU-1234177 https://reactome.org/PathwayBrowser/#/R-MMU-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Mus musculus 16810 R-MMU-1234181 https://reactome.org/PathwayBrowser/#/R-MMU-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Mus musculus 16810 R-MMU-1650808 https://reactome.org/PathwayBrowser/#/R-MMU-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Mus musculus 16810 R-MMU-1980233 https://reactome.org/PathwayBrowser/#/R-MMU-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Mus musculus 16810 R-MMU-1981104 https://reactome.org/PathwayBrowser/#/R-MMU-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Mus musculus 16810 R-MMU-198440 https://reactome.org/PathwayBrowser/#/R-MMU-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Mus musculus 16810 R-MMU-372480 https://reactome.org/PathwayBrowser/#/R-MMU-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Mus musculus 16810 R-MMU-376851 https://reactome.org/PathwayBrowser/#/R-MMU-376851 SLC25A11 exchanges 2-OG and MAL IEA Mus musculus 16810 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 16810 R-MMU-389540 https://reactome.org/PathwayBrowser/#/R-MMU-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 16810 R-MMU-389550 https://reactome.org/PathwayBrowser/#/R-MMU-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 16810 R-MMU-389639 https://reactome.org/PathwayBrowser/#/R-MMU-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Mus musculus 16810 R-MMU-450984 https://reactome.org/PathwayBrowser/#/R-MMU-450984 IDH2 dimer decarboxylates isocitrate IEA Mus musculus 16810 R-MMU-4722133 https://reactome.org/PathwayBrowser/#/R-MMU-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Mus musculus 16810 R-MMU-4724279 https://reactome.org/PathwayBrowser/#/R-MMU-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Mus musculus 16810 R-MMU-4724284 https://reactome.org/PathwayBrowser/#/R-MMU-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Mus musculus 16810 R-MMU-4754176 https://reactome.org/PathwayBrowser/#/R-MMU-4754176 JMJD6 demethylates MeR3-histone H3 IEA Mus musculus 16810 R-MMU-4754181 https://reactome.org/PathwayBrowser/#/R-MMU-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Mus musculus 16810 R-MMU-4754187 https://reactome.org/PathwayBrowser/#/R-MMU-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Mus musculus 16810 R-MMU-507749 https://reactome.org/PathwayBrowser/#/R-MMU-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Mus musculus 16810 R-MMU-507775 https://reactome.org/PathwayBrowser/#/R-MMU-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Mus musculus 16810 R-MMU-508179 https://reactome.org/PathwayBrowser/#/R-MMU-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Mus musculus 16810 R-MMU-508189 https://reactome.org/PathwayBrowser/#/R-MMU-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Mus musculus 16810 R-MMU-508561 https://reactome.org/PathwayBrowser/#/R-MMU-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Mus musculus 16810 R-MMU-517444 https://reactome.org/PathwayBrowser/#/R-MMU-517444 TAT aminates HPP IEA Mus musculus 16810 R-MMU-5220931 https://reactome.org/PathwayBrowser/#/R-MMU-5220931 Tet1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine TAS Mus musculus 16810 R-MMU-5220936 https://reactome.org/PathwayBrowser/#/R-MMU-5220936 Tet1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine TAS Mus musculus 16810 R-MMU-5220944 https://reactome.org/PathwayBrowser/#/R-MMU-5220944 Tet1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine TAS Mus musculus 16810 R-MMU-5423117 https://reactome.org/PathwayBrowser/#/R-MMU-5423117 PHF8 demethylates MeK21-histone H4 IEA Mus musculus 16810 R-MMU-561041 https://reactome.org/PathwayBrowser/#/R-MMU-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Mus musculus 16810 R-MMU-561059 https://reactome.org/PathwayBrowser/#/R-MMU-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Mus musculus 16810 R-MMU-5661114 https://reactome.org/PathwayBrowser/#/R-MMU-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Mus musculus 16810 R-MMU-5661115 https://reactome.org/PathwayBrowser/#/R-MMU-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Mus musculus 16810 R-MMU-5661116 https://reactome.org/PathwayBrowser/#/R-MMU-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Mus musculus 16810 R-MMU-5661120 https://reactome.org/PathwayBrowser/#/R-MMU-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Mus musculus 16810 R-MMU-5661121 https://reactome.org/PathwayBrowser/#/R-MMU-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Mus musculus 16810 R-MMU-5661122 https://reactome.org/PathwayBrowser/#/R-MMU-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Mus musculus 16810 R-MMU-5661124 https://reactome.org/PathwayBrowser/#/R-MMU-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Mus musculus 16810 R-MMU-5661125 https://reactome.org/PathwayBrowser/#/R-MMU-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Mus musculus 16810 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 16810 R-MMU-70523 https://reactome.org/PathwayBrowser/#/R-MMU-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Mus musculus 16810 R-MMU-70524 https://reactome.org/PathwayBrowser/#/R-MMU-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Mus musculus 16810 R-MMU-70581 https://reactome.org/PathwayBrowser/#/R-MMU-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Mus musculus 16810 R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Mus musculus 16810 R-MMU-70592 https://reactome.org/PathwayBrowser/#/R-MMU-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Mus musculus 16810 R-MMU-70596 https://reactome.org/PathwayBrowser/#/R-MMU-70596 GOT2 dimer deaminates L-Asp IEA Mus musculus 16810 R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Mus musculus 16810 R-MMU-70613 https://reactome.org/PathwayBrowser/#/R-MMU-70613 GOT2 transaminates OA and L-Glu IEA Mus musculus 16810 R-MMU-70654 https://reactome.org/PathwayBrowser/#/R-MMU-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Mus musculus 16810 R-MMU-70666 https://reactome.org/PathwayBrowser/#/R-MMU-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Mus musculus 16810 R-MMU-70723 https://reactome.org/PathwayBrowser/#/R-MMU-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Mus musculus 16810 R-MMU-70724 https://reactome.org/PathwayBrowser/#/R-MMU-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Mus musculus 16810 R-MMU-70938 https://reactome.org/PathwayBrowser/#/R-MMU-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Mus musculus 16810 R-MMU-70952 https://reactome.org/PathwayBrowser/#/R-MMU-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Mus musculus 16810 R-MMU-70967 https://reactome.org/PathwayBrowser/#/R-MMU-70967 IDH3 complex decarboxylates isocitrate IEA Mus musculus 16810 R-MMU-71155 https://reactome.org/PathwayBrowser/#/R-MMU-71155 TAT deaminates tyrosine IEA Mus musculus 16810 R-MMU-71241 https://reactome.org/PathwayBrowser/#/R-MMU-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Mus musculus 16810 R-MMU-71261 https://reactome.org/PathwayBrowser/#/R-MMU-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Mus musculus 16810 R-MMU-71401 https://reactome.org/PathwayBrowser/#/R-MMU-71401 OGDH dimer decarboxylates 2-OG IEA Mus musculus 16810 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 16810 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 16810 R-MMU-880002 https://reactome.org/PathwayBrowser/#/R-MMU-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Mus musculus 16810 R-MMU-880007 https://reactome.org/PathwayBrowser/#/R-MMU-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Mus musculus 16810 R-MMU-880033 https://reactome.org/PathwayBrowser/#/R-MMU-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Mus musculus 16810 R-MMU-880050 https://reactome.org/PathwayBrowser/#/R-MMU-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Mus musculus 16810 R-MMU-8857692 https://reactome.org/PathwayBrowser/#/R-MMU-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Mus musculus 16810 R-MMU-893583 https://reactome.org/PathwayBrowser/#/R-MMU-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Mus musculus 16810 R-MMU-916855 https://reactome.org/PathwayBrowser/#/R-MMU-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Mus musculus 16810 R-MMU-9629578 https://reactome.org/PathwayBrowser/#/R-MMU-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Mus musculus 16810 R-MMU-9629591 https://reactome.org/PathwayBrowser/#/R-MMU-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Mus musculus 16810 R-MMU-9629869 https://reactome.org/PathwayBrowser/#/R-MMU-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Mus musculus 16810 R-MMU-9629888 https://reactome.org/PathwayBrowser/#/R-MMU-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Mus musculus 16810 R-MMU-9629946 https://reactome.org/PathwayBrowser/#/R-MMU-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Mus musculus 16810 R-MMU-9630022 https://reactome.org/PathwayBrowser/#/R-MMU-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Mus musculus 16810 R-MMU-9630769 https://reactome.org/PathwayBrowser/#/R-MMU-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Mus musculus 16810 R-MMU-9630967 https://reactome.org/PathwayBrowser/#/R-MMU-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Mus musculus 16810 R-MMU-9630993 https://reactome.org/PathwayBrowser/#/R-MMU-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Mus musculus 16810 R-MMU-964773 https://reactome.org/PathwayBrowser/#/R-MMU-964773 OXGR1 binds 2OG IEA Mus musculus 16810 R-MMU-977333 https://reactome.org/PathwayBrowser/#/R-MMU-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Mus musculus 16810 R-MMU-9817463 https://reactome.org/PathwayBrowser/#/R-MMU-9817463 Tet3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 dimethylated on lysine-9 TAS Mus musculus 16810 R-MMU-9822448 https://reactome.org/PathwayBrowser/#/R-MMU-9822448 Kdm5b demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 16810 R-MMU-9822463 https://reactome.org/PathwayBrowser/#/R-MMU-9822463 Kdm5a demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 16810 R-MMU-9822924 https://reactome.org/PathwayBrowser/#/R-MMU-9822924 Kdm6b (Jmjd3) demethylates histone H3 trimethyllysine-27 (H3K27me3) TAS Mus musculus 16810 R-MMU-9822964 https://reactome.org/PathwayBrowser/#/R-MMU-9822964 Kdm6a (Utx) demethylates trimethylated histone H3 lysine-27 (H3K27me3) TAS Mus musculus 16810 R-PFA-198440 https://reactome.org/PathwayBrowser/#/R-PFA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Plasmodium falciparum 16810 R-PFA-2172678 https://reactome.org/PathwayBrowser/#/R-PFA-2172678 PHF8 demethylates histone H4K20me1 IEA Plasmodium falciparum 16810 R-PFA-376851 https://reactome.org/PathwayBrowser/#/R-PFA-376851 SLC25A11 exchanges 2-OG and MAL IEA Plasmodium falciparum 16810 R-PFA-450984 https://reactome.org/PathwayBrowser/#/R-PFA-450984 IDH2 dimer decarboxylates isocitrate IEA Plasmodium falciparum 16810 R-PFA-4724284 https://reactome.org/PathwayBrowser/#/R-PFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Plasmodium falciparum 16810 R-PFA-5661115 https://reactome.org/PathwayBrowser/#/R-PFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Plasmodium falciparum 16810 R-PFA-70581 https://reactome.org/PathwayBrowser/#/R-PFA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Plasmodium falciparum 16810 R-PFA-70592 https://reactome.org/PathwayBrowser/#/R-PFA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Plasmodium falciparum 16810 R-PFA-70654 https://reactome.org/PathwayBrowser/#/R-PFA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Plasmodium falciparum 16810 R-PFA-70666 https://reactome.org/PathwayBrowser/#/R-PFA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Plasmodium falciparum 16810 R-PFA-71401 https://reactome.org/PathwayBrowser/#/R-PFA-71401 OGDH dimer decarboxylates 2-OG IEA Plasmodium falciparum 16810 R-RNO-1234164 https://reactome.org/PathwayBrowser/#/R-RNO-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Rattus norvegicus 16810 R-RNO-1234165 https://reactome.org/PathwayBrowser/#/R-RNO-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 16810 R-RNO-1234173 https://reactome.org/PathwayBrowser/#/R-RNO-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 16810 R-RNO-1234177 https://reactome.org/PathwayBrowser/#/R-RNO-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 16810 R-RNO-1234181 https://reactome.org/PathwayBrowser/#/R-RNO-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 16810 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus 16810 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus 16810 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus 16810 R-RNO-198440 https://reactome.org/PathwayBrowser/#/R-RNO-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Rattus norvegicus 16810 R-RNO-2172678 https://reactome.org/PathwayBrowser/#/R-RNO-2172678 PHF8 demethylates histone H4K20me1 IEA Rattus norvegicus 16810 R-RNO-3222593 https://reactome.org/PathwayBrowser/#/R-RNO-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Rattus norvegicus 16810 R-RNO-372480 https://reactome.org/PathwayBrowser/#/R-RNO-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Rattus norvegicus 16810 R-RNO-376851 https://reactome.org/PathwayBrowser/#/R-RNO-376851 SLC25A11 exchanges 2-OG and MAL IEA Rattus norvegicus 16810 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 16810 R-RNO-389540 https://reactome.org/PathwayBrowser/#/R-RNO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 16810 R-RNO-389550 https://reactome.org/PathwayBrowser/#/R-RNO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 16810 R-RNO-389639 https://reactome.org/PathwayBrowser/#/R-RNO-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Rattus norvegicus 16810 R-RNO-450984 https://reactome.org/PathwayBrowser/#/R-RNO-450984 IDH2 dimer decarboxylates isocitrate IEA Rattus norvegicus 16810 R-RNO-4722133 https://reactome.org/PathwayBrowser/#/R-RNO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Rattus norvegicus 16810 R-RNO-4724279 https://reactome.org/PathwayBrowser/#/R-RNO-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Rattus norvegicus 16810 R-RNO-4724284 https://reactome.org/PathwayBrowser/#/R-RNO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Rattus norvegicus 16810 R-RNO-4754176 https://reactome.org/PathwayBrowser/#/R-RNO-4754176 JMJD6 demethylates MeR3-histone H3 IEA Rattus norvegicus 16810 R-RNO-4754181 https://reactome.org/PathwayBrowser/#/R-RNO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Rattus norvegicus 16810 R-RNO-4754187 https://reactome.org/PathwayBrowser/#/R-RNO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Rattus norvegicus 16810 R-RNO-507749 https://reactome.org/PathwayBrowser/#/R-RNO-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Rattus norvegicus 16810 R-RNO-507775 https://reactome.org/PathwayBrowser/#/R-RNO-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Rattus norvegicus 16810 R-RNO-508179 https://reactome.org/PathwayBrowser/#/R-RNO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Rattus norvegicus 16810 R-RNO-508189 https://reactome.org/PathwayBrowser/#/R-RNO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Rattus norvegicus 16810 R-RNO-508561 https://reactome.org/PathwayBrowser/#/R-RNO-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Rattus norvegicus 16810 R-RNO-517444 https://reactome.org/PathwayBrowser/#/R-RNO-517444 TAT aminates HPP IEA Rattus norvegicus 16810 R-RNO-5423117 https://reactome.org/PathwayBrowser/#/R-RNO-5423117 PHF8 demethylates MeK21-histone H4 IEA Rattus norvegicus 16810 R-RNO-561041 https://reactome.org/PathwayBrowser/#/R-RNO-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Rattus norvegicus 16810 R-RNO-561059 https://reactome.org/PathwayBrowser/#/R-RNO-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Rattus norvegicus 16810 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 16810 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 16810 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 16810 R-RNO-5661114 https://reactome.org/PathwayBrowser/#/R-RNO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Rattus norvegicus 16810 R-RNO-5661115 https://reactome.org/PathwayBrowser/#/R-RNO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Rattus norvegicus 16810 R-RNO-5661116 https://reactome.org/PathwayBrowser/#/R-RNO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Rattus norvegicus 16810 R-RNO-5661120 https://reactome.org/PathwayBrowser/#/R-RNO-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Rattus norvegicus 16810 R-RNO-5661121 https://reactome.org/PathwayBrowser/#/R-RNO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Rattus norvegicus 16810 R-RNO-5661122 https://reactome.org/PathwayBrowser/#/R-RNO-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Rattus norvegicus 16810 R-RNO-5661124 https://reactome.org/PathwayBrowser/#/R-RNO-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Rattus norvegicus 16810 R-RNO-5661125 https://reactome.org/PathwayBrowser/#/R-RNO-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Rattus norvegicus 16810 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 16810 R-RNO-70523 https://reactome.org/PathwayBrowser/#/R-RNO-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Rattus norvegicus 16810 R-RNO-70524 https://reactome.org/PathwayBrowser/#/R-RNO-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Rattus norvegicus 16810 R-RNO-70581 https://reactome.org/PathwayBrowser/#/R-RNO-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Rattus norvegicus 16810 R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Rattus norvegicus 16810 R-RNO-70592 https://reactome.org/PathwayBrowser/#/R-RNO-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Rattus norvegicus 16810 R-RNO-70596 https://reactome.org/PathwayBrowser/#/R-RNO-70596 GOT2 dimer deaminates L-Asp IEA Rattus norvegicus 16810 R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Rattus norvegicus 16810 R-RNO-70613 https://reactome.org/PathwayBrowser/#/R-RNO-70613 GOT2 transaminates OA and L-Glu IEA Rattus norvegicus 16810 R-RNO-70654 https://reactome.org/PathwayBrowser/#/R-RNO-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Rattus norvegicus 16810 R-RNO-70666 https://reactome.org/PathwayBrowser/#/R-RNO-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Rattus norvegicus 16810 R-RNO-70723 https://reactome.org/PathwayBrowser/#/R-RNO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Rattus norvegicus 16810 R-RNO-70724 https://reactome.org/PathwayBrowser/#/R-RNO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Rattus norvegicus 16810 R-RNO-70938 https://reactome.org/PathwayBrowser/#/R-RNO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Rattus norvegicus 16810 R-RNO-70952 https://reactome.org/PathwayBrowser/#/R-RNO-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Rattus norvegicus 16810 R-RNO-70967 https://reactome.org/PathwayBrowser/#/R-RNO-70967 IDH3 complex decarboxylates isocitrate IEA Rattus norvegicus 16810 R-RNO-71155 https://reactome.org/PathwayBrowser/#/R-RNO-71155 TAT deaminates tyrosine IEA Rattus norvegicus 16810 R-RNO-71241 https://reactome.org/PathwayBrowser/#/R-RNO-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Rattus norvegicus 16810 R-RNO-71261 https://reactome.org/PathwayBrowser/#/R-RNO-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Rattus norvegicus 16810 R-RNO-71401 https://reactome.org/PathwayBrowser/#/R-RNO-71401 OGDH dimer decarboxylates 2-OG IEA Rattus norvegicus 16810 R-RNO-880002 https://reactome.org/PathwayBrowser/#/R-RNO-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Rattus norvegicus 16810 R-RNO-880007 https://reactome.org/PathwayBrowser/#/R-RNO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Rattus norvegicus 16810 R-RNO-880033 https://reactome.org/PathwayBrowser/#/R-RNO-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Rattus norvegicus 16810 R-RNO-880050 https://reactome.org/PathwayBrowser/#/R-RNO-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Rattus norvegicus 16810 R-RNO-8857692 https://reactome.org/PathwayBrowser/#/R-RNO-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Rattus norvegicus 16810 R-RNO-893583 https://reactome.org/PathwayBrowser/#/R-RNO-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Rattus norvegicus 16810 R-RNO-9012709 https://reactome.org/PathwayBrowser/#/R-RNO-9012709 Got2:PLXP dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu TAS Rattus norvegicus 16810 R-RNO-916855 https://reactome.org/PathwayBrowser/#/R-RNO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Rattus norvegicus 16810 R-RNO-9629578 https://reactome.org/PathwayBrowser/#/R-RNO-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Rattus norvegicus 16810 R-RNO-9629591 https://reactome.org/PathwayBrowser/#/R-RNO-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Rattus norvegicus 16810 R-RNO-9629869 https://reactome.org/PathwayBrowser/#/R-RNO-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Rattus norvegicus 16810 R-RNO-9629888 https://reactome.org/PathwayBrowser/#/R-RNO-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Rattus norvegicus 16810 R-RNO-9629946 https://reactome.org/PathwayBrowser/#/R-RNO-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Rattus norvegicus 16810 R-RNO-9630022 https://reactome.org/PathwayBrowser/#/R-RNO-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Rattus norvegicus 16810 R-RNO-9630769 https://reactome.org/PathwayBrowser/#/R-RNO-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Rattus norvegicus 16810 R-RNO-9630967 https://reactome.org/PathwayBrowser/#/R-RNO-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Rattus norvegicus 16810 R-RNO-9630993 https://reactome.org/PathwayBrowser/#/R-RNO-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Rattus norvegicus 16810 R-RNO-964773 https://reactome.org/PathwayBrowser/#/R-RNO-964773 OXGR1 binds 2OG IEA Rattus norvegicus 16810 R-RNO-977333 https://reactome.org/PathwayBrowser/#/R-RNO-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Rattus norvegicus 16810 R-SCE-2172678 https://reactome.org/PathwayBrowser/#/R-SCE-2172678 PHF8 demethylates histone H4K20me1 IEA Saccharomyces cerevisiae 16810 R-SCE-3222593 https://reactome.org/PathwayBrowser/#/R-SCE-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Saccharomyces cerevisiae 16810 R-SCE-389540 https://reactome.org/PathwayBrowser/#/R-SCE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 16810 R-SCE-389550 https://reactome.org/PathwayBrowser/#/R-SCE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 16810 R-SCE-389639 https://reactome.org/PathwayBrowser/#/R-SCE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Saccharomyces cerevisiae 16810 R-SCE-4722133 https://reactome.org/PathwayBrowser/#/R-SCE-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Saccharomyces cerevisiae 16810 R-SCE-4724279 https://reactome.org/PathwayBrowser/#/R-SCE-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Saccharomyces cerevisiae 16810 R-SCE-4754181 https://reactome.org/PathwayBrowser/#/R-SCE-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Saccharomyces cerevisiae 16810 R-SCE-4754187 https://reactome.org/PathwayBrowser/#/R-SCE-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Saccharomyces cerevisiae 16810 R-SCE-507749 https://reactome.org/PathwayBrowser/#/R-SCE-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Saccharomyces cerevisiae 16810 R-SCE-507775 https://reactome.org/PathwayBrowser/#/R-SCE-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Saccharomyces cerevisiae 16810 R-SCE-508179 https://reactome.org/PathwayBrowser/#/R-SCE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Saccharomyces cerevisiae 16810 R-SCE-508189 https://reactome.org/PathwayBrowser/#/R-SCE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Saccharomyces cerevisiae 16810 R-SCE-508561 https://reactome.org/PathwayBrowser/#/R-SCE-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Saccharomyces cerevisiae 16810 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16810 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16810 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16810 R-SCE-5661114 https://reactome.org/PathwayBrowser/#/R-SCE-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Saccharomyces cerevisiae 16810 R-SCE-5661116 https://reactome.org/PathwayBrowser/#/R-SCE-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Saccharomyces cerevisiae 16810 R-SCE-5661120 https://reactome.org/PathwayBrowser/#/R-SCE-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Saccharomyces cerevisiae 16810 R-SCE-5661121 https://reactome.org/PathwayBrowser/#/R-SCE-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Saccharomyces cerevisiae 16810 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 16810 R-SCE-70523 https://reactome.org/PathwayBrowser/#/R-SCE-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Saccharomyces cerevisiae 16810 R-SCE-70524 https://reactome.org/PathwayBrowser/#/R-SCE-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Saccharomyces cerevisiae 16810 R-SCE-70581 https://reactome.org/PathwayBrowser/#/R-SCE-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Saccharomyces cerevisiae 16810 R-SCE-70592 https://reactome.org/PathwayBrowser/#/R-SCE-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Saccharomyces cerevisiae 16810 R-SCE-70596 https://reactome.org/PathwayBrowser/#/R-SCE-70596 GOT2 dimer deaminates L-Asp IEA Saccharomyces cerevisiae 16810 R-SCE-70613 https://reactome.org/PathwayBrowser/#/R-SCE-70613 GOT2 transaminates OA and L-Glu IEA Saccharomyces cerevisiae 16810 R-SCE-70654 https://reactome.org/PathwayBrowser/#/R-SCE-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Saccharomyces cerevisiae 16810 R-SCE-70666 https://reactome.org/PathwayBrowser/#/R-SCE-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Saccharomyces cerevisiae 16810 R-SCE-70723 https://reactome.org/PathwayBrowser/#/R-SCE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Saccharomyces cerevisiae 16810 R-SCE-70724 https://reactome.org/PathwayBrowser/#/R-SCE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Saccharomyces cerevisiae 16810 R-SCE-70938 https://reactome.org/PathwayBrowser/#/R-SCE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Saccharomyces cerevisiae 16810 R-SCE-70952 https://reactome.org/PathwayBrowser/#/R-SCE-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Saccharomyces cerevisiae 16810 R-SCE-70967 https://reactome.org/PathwayBrowser/#/R-SCE-70967 IDH3 complex decarboxylates isocitrate IEA Saccharomyces cerevisiae 16810 R-SCE-71261 https://reactome.org/PathwayBrowser/#/R-SCE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Saccharomyces cerevisiae 16810 R-SCE-71401 https://reactome.org/PathwayBrowser/#/R-SCE-71401 OGDH dimer decarboxylates 2-OG IEA Saccharomyces cerevisiae 16810 R-SCE-880007 https://reactome.org/PathwayBrowser/#/R-SCE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Saccharomyces cerevisiae 16810 R-SCE-893583 https://reactome.org/PathwayBrowser/#/R-SCE-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Saccharomyces cerevisiae 16810 R-SCE-916855 https://reactome.org/PathwayBrowser/#/R-SCE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Saccharomyces cerevisiae 16810 R-SCE-9630769 https://reactome.org/PathwayBrowser/#/R-SCE-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Saccharomyces cerevisiae 16810 R-SCE-977333 https://reactome.org/PathwayBrowser/#/R-SCE-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Saccharomyces cerevisiae 16810 R-SPO-2172678 https://reactome.org/PathwayBrowser/#/R-SPO-2172678 PHF8 demethylates histone H4K20me1 IEA Schizosaccharomyces pombe 16810 R-SPO-3222593 https://reactome.org/PathwayBrowser/#/R-SPO-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Schizosaccharomyces pombe 16810 R-SPO-389540 https://reactome.org/PathwayBrowser/#/R-SPO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 16810 R-SPO-389550 https://reactome.org/PathwayBrowser/#/R-SPO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 16810 R-SPO-4722133 https://reactome.org/PathwayBrowser/#/R-SPO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Schizosaccharomyces pombe 16810 R-SPO-4724284 https://reactome.org/PathwayBrowser/#/R-SPO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Schizosaccharomyces pombe 16810 R-SPO-4754181 https://reactome.org/PathwayBrowser/#/R-SPO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Schizosaccharomyces pombe 16810 R-SPO-4754187 https://reactome.org/PathwayBrowser/#/R-SPO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Schizosaccharomyces pombe 16810 R-SPO-508179 https://reactome.org/PathwayBrowser/#/R-SPO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Schizosaccharomyces pombe 16810 R-SPO-508189 https://reactome.org/PathwayBrowser/#/R-SPO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Schizosaccharomyces pombe 16810 R-SPO-508561 https://reactome.org/PathwayBrowser/#/R-SPO-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Schizosaccharomyces pombe 16810 R-SPO-5423117 https://reactome.org/PathwayBrowser/#/R-SPO-5423117 PHF8 demethylates MeK21-histone H4 IEA Schizosaccharomyces pombe 16810 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16810 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16810 R-SPO-5661114 https://reactome.org/PathwayBrowser/#/R-SPO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Schizosaccharomyces pombe 16810 R-SPO-5661115 https://reactome.org/PathwayBrowser/#/R-SPO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Schizosaccharomyces pombe 16810 R-SPO-5661116 https://reactome.org/PathwayBrowser/#/R-SPO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Schizosaccharomyces pombe 16810 R-SPO-5661121 https://reactome.org/PathwayBrowser/#/R-SPO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Schizosaccharomyces pombe 16810 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 16810 R-SPO-70581 https://reactome.org/PathwayBrowser/#/R-SPO-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Schizosaccharomyces pombe 16810 R-SPO-70592 https://reactome.org/PathwayBrowser/#/R-SPO-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Schizosaccharomyces pombe 16810 R-SPO-70596 https://reactome.org/PathwayBrowser/#/R-SPO-70596 GOT2 dimer deaminates L-Asp IEA Schizosaccharomyces pombe 16810 R-SPO-70613 https://reactome.org/PathwayBrowser/#/R-SPO-70613 GOT2 transaminates OA and L-Glu IEA Schizosaccharomyces pombe 16810 R-SPO-70654 https://reactome.org/PathwayBrowser/#/R-SPO-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Schizosaccharomyces pombe 16810 R-SPO-70666 https://reactome.org/PathwayBrowser/#/R-SPO-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Schizosaccharomyces pombe 16810 R-SPO-70723 https://reactome.org/PathwayBrowser/#/R-SPO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Schizosaccharomyces pombe 16810 R-SPO-70724 https://reactome.org/PathwayBrowser/#/R-SPO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Schizosaccharomyces pombe 16810 R-SPO-70938 https://reactome.org/PathwayBrowser/#/R-SPO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Schizosaccharomyces pombe 16810 R-SPO-70952 https://reactome.org/PathwayBrowser/#/R-SPO-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Schizosaccharomyces pombe 16810 R-SPO-70967 https://reactome.org/PathwayBrowser/#/R-SPO-70967 IDH3 complex decarboxylates isocitrate IEA Schizosaccharomyces pombe 16810 R-SPO-71401 https://reactome.org/PathwayBrowser/#/R-SPO-71401 OGDH dimer decarboxylates 2-OG IEA Schizosaccharomyces pombe 16810 R-SPO-880007 https://reactome.org/PathwayBrowser/#/R-SPO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Schizosaccharomyces pombe 16810 R-SPO-893583 https://reactome.org/PathwayBrowser/#/R-SPO-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Schizosaccharomyces pombe 16810 R-SPO-916855 https://reactome.org/PathwayBrowser/#/R-SPO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Schizosaccharomyces pombe 16810 R-SPO-9629946 https://reactome.org/PathwayBrowser/#/R-SPO-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Schizosaccharomyces pombe 16810 R-SPO-9630769 https://reactome.org/PathwayBrowser/#/R-SPO-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Schizosaccharomyces pombe 16810 R-SPO-977333 https://reactome.org/PathwayBrowser/#/R-SPO-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Schizosaccharomyces pombe 16810 R-SSC-1234164 https://reactome.org/PathwayBrowser/#/R-SSC-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Sus scrofa 16810 R-SSC-1234165 https://reactome.org/PathwayBrowser/#/R-SSC-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 16810 R-SSC-1234173 https://reactome.org/PathwayBrowser/#/R-SSC-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 16810 R-SSC-1234177 https://reactome.org/PathwayBrowser/#/R-SSC-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 16810 R-SSC-1234181 https://reactome.org/PathwayBrowser/#/R-SSC-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 16810 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa 16810 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa 16810 R-SSC-198440 https://reactome.org/PathwayBrowser/#/R-SSC-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Sus scrofa 16810 R-SSC-2172678 https://reactome.org/PathwayBrowser/#/R-SSC-2172678 PHF8 demethylates histone H4K20me1 IEA Sus scrofa 16810 R-SSC-3222593 https://reactome.org/PathwayBrowser/#/R-SSC-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Sus scrofa 16810 R-SSC-372480 https://reactome.org/PathwayBrowser/#/R-SSC-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Sus scrofa 16810 R-SSC-376851 https://reactome.org/PathwayBrowser/#/R-SSC-376851 SLC25A11 exchanges 2-OG and MAL IEA Sus scrofa 16810 R-SSC-389540 https://reactome.org/PathwayBrowser/#/R-SSC-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 16810 R-SSC-389550 https://reactome.org/PathwayBrowser/#/R-SSC-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 16810 R-SSC-389639 https://reactome.org/PathwayBrowser/#/R-SSC-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Sus scrofa 16810 R-SSC-450984 https://reactome.org/PathwayBrowser/#/R-SSC-450984 IDH2 dimer decarboxylates isocitrate IEA Sus scrofa 16810 R-SSC-4722133 https://reactome.org/PathwayBrowser/#/R-SSC-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Sus scrofa 16810 R-SSC-4724279 https://reactome.org/PathwayBrowser/#/R-SSC-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Sus scrofa 16810 R-SSC-4724284 https://reactome.org/PathwayBrowser/#/R-SSC-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Sus scrofa 16810 R-SSC-4754176 https://reactome.org/PathwayBrowser/#/R-SSC-4754176 JMJD6 demethylates MeR3-histone H3 IEA Sus scrofa 16810 R-SSC-4754181 https://reactome.org/PathwayBrowser/#/R-SSC-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Sus scrofa 16810 R-SSC-4754187 https://reactome.org/PathwayBrowser/#/R-SSC-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Sus scrofa 16810 R-SSC-507749 https://reactome.org/PathwayBrowser/#/R-SSC-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Sus scrofa 16810 R-SSC-507775 https://reactome.org/PathwayBrowser/#/R-SSC-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Sus scrofa 16810 R-SSC-508179 https://reactome.org/PathwayBrowser/#/R-SSC-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Sus scrofa 16810 R-SSC-508189 https://reactome.org/PathwayBrowser/#/R-SSC-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Sus scrofa 16810 R-SSC-508561 https://reactome.org/PathwayBrowser/#/R-SSC-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Sus scrofa 16810 R-SSC-517444 https://reactome.org/PathwayBrowser/#/R-SSC-517444 TAT aminates HPP IEA Sus scrofa 16810 R-SSC-5423117 https://reactome.org/PathwayBrowser/#/R-SSC-5423117 PHF8 demethylates MeK21-histone H4 IEA Sus scrofa 16810 R-SSC-561041 https://reactome.org/PathwayBrowser/#/R-SSC-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Sus scrofa 16810 R-SSC-561059 https://reactome.org/PathwayBrowser/#/R-SSC-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Sus scrofa 16810 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 16810 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 16810 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 16810 R-SSC-5661114 https://reactome.org/PathwayBrowser/#/R-SSC-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Sus scrofa 16810 R-SSC-5661115 https://reactome.org/PathwayBrowser/#/R-SSC-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Sus scrofa 16810 R-SSC-5661116 https://reactome.org/PathwayBrowser/#/R-SSC-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Sus scrofa 16810 R-SSC-5661120 https://reactome.org/PathwayBrowser/#/R-SSC-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Sus scrofa 16810 R-SSC-5661121 https://reactome.org/PathwayBrowser/#/R-SSC-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Sus scrofa 16810 R-SSC-5661122 https://reactome.org/PathwayBrowser/#/R-SSC-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Sus scrofa 16810 R-SSC-5661124 https://reactome.org/PathwayBrowser/#/R-SSC-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Sus scrofa 16810 R-SSC-5661125 https://reactome.org/PathwayBrowser/#/R-SSC-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Sus scrofa 16810 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 16810 R-SSC-70523 https://reactome.org/PathwayBrowser/#/R-SSC-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Sus scrofa 16810 R-SSC-70524 https://reactome.org/PathwayBrowser/#/R-SSC-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Sus scrofa 16810 R-SSC-70581 https://reactome.org/PathwayBrowser/#/R-SSC-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Sus scrofa 16810 R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Sus scrofa 16810 R-SSC-70592 https://reactome.org/PathwayBrowser/#/R-SSC-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Sus scrofa 16810 R-SSC-70596 https://reactome.org/PathwayBrowser/#/R-SSC-70596 GOT2 dimer deaminates L-Asp IEA Sus scrofa 16810 R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Sus scrofa 16810 R-SSC-70613 https://reactome.org/PathwayBrowser/#/R-SSC-70613 GOT2 transaminates OA and L-Glu IEA Sus scrofa 16810 R-SSC-70654 https://reactome.org/PathwayBrowser/#/R-SSC-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Sus scrofa 16810 R-SSC-70666 https://reactome.org/PathwayBrowser/#/R-SSC-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Sus scrofa 16810 R-SSC-70723 https://reactome.org/PathwayBrowser/#/R-SSC-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Sus scrofa 16810 R-SSC-70724 https://reactome.org/PathwayBrowser/#/R-SSC-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Sus scrofa 16810 R-SSC-70938 https://reactome.org/PathwayBrowser/#/R-SSC-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Sus scrofa 16810 R-SSC-70952 https://reactome.org/PathwayBrowser/#/R-SSC-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Sus scrofa 16810 R-SSC-70967 https://reactome.org/PathwayBrowser/#/R-SSC-70967 IDH3 complex decarboxylates isocitrate IEA Sus scrofa 16810 R-SSC-71155 https://reactome.org/PathwayBrowser/#/R-SSC-71155 TAT deaminates tyrosine IEA Sus scrofa 16810 R-SSC-71241 https://reactome.org/PathwayBrowser/#/R-SSC-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Sus scrofa 16810 R-SSC-71261 https://reactome.org/PathwayBrowser/#/R-SSC-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Sus scrofa 16810 R-SSC-71401 https://reactome.org/PathwayBrowser/#/R-SSC-71401 OGDH dimer decarboxylates 2-OG IEA Sus scrofa 16810 R-SSC-880002 https://reactome.org/PathwayBrowser/#/R-SSC-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Sus scrofa 16810 R-SSC-880007 https://reactome.org/PathwayBrowser/#/R-SSC-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa 16810 R-SSC-880033 https://reactome.org/PathwayBrowser/#/R-SSC-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Sus scrofa 16810 R-SSC-880050 https://reactome.org/PathwayBrowser/#/R-SSC-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa 16810 R-SSC-8857692 https://reactome.org/PathwayBrowser/#/R-SSC-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Sus scrofa 16810 R-SSC-893583 https://reactome.org/PathwayBrowser/#/R-SSC-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Sus scrofa 16810 R-SSC-916855 https://reactome.org/PathwayBrowser/#/R-SSC-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Sus scrofa 16810 R-SSC-9629578 https://reactome.org/PathwayBrowser/#/R-SSC-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Sus scrofa 16810 R-SSC-9629591 https://reactome.org/PathwayBrowser/#/R-SSC-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Sus scrofa 16810 R-SSC-9629869 https://reactome.org/PathwayBrowser/#/R-SSC-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Sus scrofa 16810 R-SSC-9629888 https://reactome.org/PathwayBrowser/#/R-SSC-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Sus scrofa 16810 R-SSC-9629946 https://reactome.org/PathwayBrowser/#/R-SSC-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Sus scrofa 16810 R-SSC-9630022 https://reactome.org/PathwayBrowser/#/R-SSC-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Sus scrofa 16810 R-SSC-9630769 https://reactome.org/PathwayBrowser/#/R-SSC-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Sus scrofa 16810 R-SSC-9630967 https://reactome.org/PathwayBrowser/#/R-SSC-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Sus scrofa 16810 R-SSC-9630993 https://reactome.org/PathwayBrowser/#/R-SSC-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Sus scrofa 16810 R-SSC-977333 https://reactome.org/PathwayBrowser/#/R-SSC-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Sus scrofa 16810 R-XTR-1234164 https://reactome.org/PathwayBrowser/#/R-XTR-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Xenopus tropicalis 16810 R-XTR-1234165 https://reactome.org/PathwayBrowser/#/R-XTR-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 16810 R-XTR-1234173 https://reactome.org/PathwayBrowser/#/R-XTR-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 16810 R-XTR-1234177 https://reactome.org/PathwayBrowser/#/R-XTR-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 16810 R-XTR-1234181 https://reactome.org/PathwayBrowser/#/R-XTR-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 16810 R-XTR-1650808 https://reactome.org/PathwayBrowser/#/R-XTR-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Xenopus tropicalis 16810 R-XTR-1980233 https://reactome.org/PathwayBrowser/#/R-XTR-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Xenopus tropicalis 16810 R-XTR-1981104 https://reactome.org/PathwayBrowser/#/R-XTR-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Xenopus tropicalis 16810 R-XTR-198440 https://reactome.org/PathwayBrowser/#/R-XTR-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Xenopus tropicalis 16810 R-XTR-2172678 https://reactome.org/PathwayBrowser/#/R-XTR-2172678 PHF8 demethylates histone H4K20me1 IEA Xenopus tropicalis 16810 R-XTR-3222593 https://reactome.org/PathwayBrowser/#/R-XTR-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Xenopus tropicalis 16810 R-XTR-372480 https://reactome.org/PathwayBrowser/#/R-XTR-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Xenopus tropicalis 16810 R-XTR-376851 https://reactome.org/PathwayBrowser/#/R-XTR-376851 SLC25A11 exchanges 2-OG and MAL IEA Xenopus tropicalis 16810 R-XTR-389540 https://reactome.org/PathwayBrowser/#/R-XTR-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 16810 R-XTR-389550 https://reactome.org/PathwayBrowser/#/R-XTR-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 16810 R-XTR-389639 https://reactome.org/PathwayBrowser/#/R-XTR-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Xenopus tropicalis 16810 R-XTR-450984 https://reactome.org/PathwayBrowser/#/R-XTR-450984 IDH2 dimer decarboxylates isocitrate IEA Xenopus tropicalis 16810 R-XTR-507749 https://reactome.org/PathwayBrowser/#/R-XTR-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Xenopus tropicalis 16810 R-XTR-507775 https://reactome.org/PathwayBrowser/#/R-XTR-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Xenopus tropicalis 16810 R-XTR-508179 https://reactome.org/PathwayBrowser/#/R-XTR-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Xenopus tropicalis 16810 R-XTR-508189 https://reactome.org/PathwayBrowser/#/R-XTR-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Xenopus tropicalis 16810 R-XTR-508561 https://reactome.org/PathwayBrowser/#/R-XTR-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Xenopus tropicalis 16810 R-XTR-517444 https://reactome.org/PathwayBrowser/#/R-XTR-517444 TAT aminates HPP IEA Xenopus tropicalis 16810 R-XTR-561041 https://reactome.org/PathwayBrowser/#/R-XTR-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Xenopus tropicalis 16810 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 16810 R-XTR-70523 https://reactome.org/PathwayBrowser/#/R-XTR-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Xenopus tropicalis 16810 R-XTR-70524 https://reactome.org/PathwayBrowser/#/R-XTR-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Xenopus tropicalis 16810 R-XTR-70581 https://reactome.org/PathwayBrowser/#/R-XTR-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Xenopus tropicalis 16810 R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Xenopus tropicalis 16810 R-XTR-70592 https://reactome.org/PathwayBrowser/#/R-XTR-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Xenopus tropicalis 16810 R-XTR-70596 https://reactome.org/PathwayBrowser/#/R-XTR-70596 GOT2 dimer deaminates L-Asp IEA Xenopus tropicalis 16810 R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Xenopus tropicalis 16810 R-XTR-70613 https://reactome.org/PathwayBrowser/#/R-XTR-70613 GOT2 transaminates OA and L-Glu IEA Xenopus tropicalis 16810 R-XTR-70654 https://reactome.org/PathwayBrowser/#/R-XTR-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Xenopus tropicalis 16810 R-XTR-70666 https://reactome.org/PathwayBrowser/#/R-XTR-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Xenopus tropicalis 16810 R-XTR-70723 https://reactome.org/PathwayBrowser/#/R-XTR-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Xenopus tropicalis 16810 R-XTR-70724 https://reactome.org/PathwayBrowser/#/R-XTR-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Xenopus tropicalis 16810 R-XTR-70938 https://reactome.org/PathwayBrowser/#/R-XTR-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Xenopus tropicalis 16810 R-XTR-70952 https://reactome.org/PathwayBrowser/#/R-XTR-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Xenopus tropicalis 16810 R-XTR-71155 https://reactome.org/PathwayBrowser/#/R-XTR-71155 TAT deaminates tyrosine IEA Xenopus tropicalis 16810 R-XTR-71241 https://reactome.org/PathwayBrowser/#/R-XTR-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Xenopus tropicalis 16810 R-XTR-71261 https://reactome.org/PathwayBrowser/#/R-XTR-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Xenopus tropicalis 16810 R-XTR-71401 https://reactome.org/PathwayBrowser/#/R-XTR-71401 OGDH dimer decarboxylates 2-OG IEA Xenopus tropicalis 16810 R-XTR-880002 https://reactome.org/PathwayBrowser/#/R-XTR-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Xenopus tropicalis 16810 R-XTR-880007 https://reactome.org/PathwayBrowser/#/R-XTR-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Xenopus tropicalis 16810 R-XTR-880033 https://reactome.org/PathwayBrowser/#/R-XTR-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Xenopus tropicalis 16810 R-XTR-880050 https://reactome.org/PathwayBrowser/#/R-XTR-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Xenopus tropicalis 16810 R-XTR-8857692 https://reactome.org/PathwayBrowser/#/R-XTR-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Xenopus tropicalis 16810 R-XTR-893583 https://reactome.org/PathwayBrowser/#/R-XTR-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Xenopus tropicalis 16810 R-XTR-916855 https://reactome.org/PathwayBrowser/#/R-XTR-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Xenopus tropicalis 16810 R-XTR-9629578 https://reactome.org/PathwayBrowser/#/R-XTR-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Xenopus tropicalis 16810 R-XTR-9629591 https://reactome.org/PathwayBrowser/#/R-XTR-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Xenopus tropicalis 16810 R-XTR-9629869 https://reactome.org/PathwayBrowser/#/R-XTR-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Xenopus tropicalis 16810 R-XTR-9629888 https://reactome.org/PathwayBrowser/#/R-XTR-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Xenopus tropicalis 16810 R-XTR-9630022 https://reactome.org/PathwayBrowser/#/R-XTR-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Xenopus tropicalis 16810 R-XTR-9630769 https://reactome.org/PathwayBrowser/#/R-XTR-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Xenopus tropicalis 16810 R-XTR-9630993 https://reactome.org/PathwayBrowser/#/R-XTR-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Xenopus tropicalis 16810 R-XTR-977333 https://reactome.org/PathwayBrowser/#/R-XTR-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Xenopus tropicalis 16827 R-BTA-193995 https://reactome.org/PathwayBrowser/#/R-BTA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Bos taurus 16827 R-BTA-194017 https://reactome.org/PathwayBrowser/#/R-BTA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Bos taurus 16827 R-BTA-4341025 https://reactome.org/PathwayBrowser/#/R-BTA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Bos taurus 16827 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 16827 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 16827 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 16827 R-CFA-193995 https://reactome.org/PathwayBrowser/#/R-CFA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Canis familiaris 16827 R-CFA-194017 https://reactome.org/PathwayBrowser/#/R-CFA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Canis familiaris 16827 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 16827 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 16827 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 16827 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 16827 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 16827 R-DRE-4341025 https://reactome.org/PathwayBrowser/#/R-DRE-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Danio rerio 16827 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 16827 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 16827 R-GGA-4341025 https://reactome.org/PathwayBrowser/#/R-GGA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Gallus gallus 16827 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 16827 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 16827 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 16827 R-HSA-193995 https://reactome.org/PathwayBrowser/#/R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST TAS Homo sapiens 16827 R-HSA-194017 https://reactome.org/PathwayBrowser/#/R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST TAS Homo sapiens 16827 R-HSA-4341025 https://reactome.org/PathwayBrowser/#/R-HSA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 TAS Homo sapiens 16827 R-HSA-549493 https://reactome.org/PathwayBrowser/#/R-HSA-549493 Expression of PERIOD-2 IEA Homo sapiens 16827 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 16827 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 16827 R-HSA-6785245 https://reactome.org/PathwayBrowser/#/R-HSA-6785245 Defective CYP11B2 does not oxidise CORST TAS Homo sapiens 16827 R-HSA-8848804 https://reactome.org/PathwayBrowser/#/R-HSA-8848804 HIF1A,EPAS1 promote PTK6 gene expression TAS Homo sapiens 16827 R-HSA-8856930 https://reactome.org/PathwayBrowser/#/R-HSA-8856930 EPAS1 (HIF2A) and activated NR3C1 (GCR) bind PTK6 gene TAS Homo sapiens 16827 R-HSA-8939900 https://reactome.org/PathwayBrowser/#/R-HSA-8939900 RUNX2 gene expression from proximal (P2) promoter is stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and inhibited by ESRRA:PPARG1CB and DEXA:NR3C1 IEA Homo sapiens 16827 R-HSA-9009085 https://reactome.org/PathwayBrowser/#/R-HSA-9009085 DEXA:NR3C1 complex binds RUNX2 gene proximal promoter IEA Homo sapiens 16827 R-HSA-9625693 https://reactome.org/PathwayBrowser/#/R-HSA-9625693 TRIM63 gene expression is stimulated by FOXO1 and FOXO3 IEA Homo sapiens 16827 R-HSA-9625699 https://reactome.org/PathwayBrowser/#/R-HSA-9625699 FOXO1 and NR3C1 bind TRIM63 gene promoter IEA Homo sapiens 16827 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 16827 R-HSA-9769345 https://reactome.org/PathwayBrowser/#/R-HSA-9769345 Activated glucocorticoid receptor represses NPAS4 gene transcription IEA Homo sapiens 16827 R-HSA-9769347 https://reactome.org/PathwayBrowser/#/R-HSA-9769347 Activated glucocorticoid receptor binds NPAS4 gene promoter IEA Homo sapiens 16827 R-MMU-193995 https://reactome.org/PathwayBrowser/#/R-MMU-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Mus musculus 16827 R-MMU-194017 https://reactome.org/PathwayBrowser/#/R-MMU-194017 CYP11B2 oxidises 11DCORST to CORST IEA Mus musculus 16827 R-MMU-4341025 https://reactome.org/PathwayBrowser/#/R-MMU-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Mus musculus 16827 R-MMU-549409 https://reactome.org/PathwayBrowser/#/R-MMU-549409 Expression of Period-2 (Per2) TAS Mus musculus 16827 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 16827 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 16827 R-MMU-9009091 https://reactome.org/PathwayBrowser/#/R-MMU-9009091 Nr3c1:DEXA binds Runx2 proximal promoter TAS Mus musculus 16827 R-MMU-9009102 https://reactome.org/PathwayBrowser/#/R-MMU-9009102 Runx2 gene expression from proximal (P2) promoter is stimulated by Runx2-P2 and inhibited by DEXA:Nr3c1 TAS Mus musculus 16827 R-MMU-9625700 https://reactome.org/PathwayBrowser/#/R-MMU-9625700 Foxo1 and Nr3c1 bind Trim63 gene promoter TAS Mus musculus 16827 R-MMU-9625730 https://reactome.org/PathwayBrowser/#/R-MMU-9625730 Trim63 gene expression is activated by Foxo1 and Nr3c1 TAS Mus musculus 16827 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 16827 R-MMU-9769703 https://reactome.org/PathwayBrowser/#/R-MMU-9769703 Activated glucocorticoid receptor binds Npas4 gene promoter TAS Mus musculus 16827 R-MMU-9769713 https://reactome.org/PathwayBrowser/#/R-MMU-9769713 Activated glucocorticoid receptor represses Npas4 gene transcription TAS Mus musculus 16827 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 16827 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 16827 R-RNO-193995 https://reactome.org/PathwayBrowser/#/R-RNO-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Rattus norvegicus 16827 R-RNO-194017 https://reactome.org/PathwayBrowser/#/R-RNO-194017 CYP11B2 oxidises 11DCORST to CORST IEA Rattus norvegicus 16827 R-RNO-4341025 https://reactome.org/PathwayBrowser/#/R-RNO-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Rattus norvegicus 16827 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 16827 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 16827 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 16827 R-SSC-193995 https://reactome.org/PathwayBrowser/#/R-SSC-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Sus scrofa 16827 R-SSC-194017 https://reactome.org/PathwayBrowser/#/R-SSC-194017 CYP11B2 oxidises 11DCORST to CORST IEA Sus scrofa 16827 R-SSC-4341025 https://reactome.org/PathwayBrowser/#/R-SSC-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Sus scrofa 16827 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 16827 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 16827 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 16827 R-XTR-193995 https://reactome.org/PathwayBrowser/#/R-XTR-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Xenopus tropicalis 16827 R-XTR-194017 https://reactome.org/PathwayBrowser/#/R-XTR-194017 CYP11B2 oxidises 11DCORST to CORST IEA Xenopus tropicalis 16827 R-XTR-4341025 https://reactome.org/PathwayBrowser/#/R-XTR-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Xenopus tropicalis 16827 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 16836 R-BTA-176646 https://reactome.org/PathwayBrowser/#/R-BTA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Bos taurus 16836 R-BTA-5695964 https://reactome.org/PathwayBrowser/#/R-BTA-5695964 ABHD14B hydrolyses PNPB IEA Bos taurus 16836 R-CEL-5695964 https://reactome.org/PathwayBrowser/#/R-CEL-5695964 ABHD14B hydrolyses PNPB IEA Caenorhabditis elegans 16836 R-CFA-176646 https://reactome.org/PathwayBrowser/#/R-CFA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Canis familiaris 16836 R-CFA-5695964 https://reactome.org/PathwayBrowser/#/R-CFA-5695964 ABHD14B hydrolyses PNPB IEA Canis familiaris 16836 R-DME-176646 https://reactome.org/PathwayBrowser/#/R-DME-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Drosophila melanogaster 16836 R-DRE-176646 https://reactome.org/PathwayBrowser/#/R-DRE-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Danio rerio 16836 R-DRE-5695964 https://reactome.org/PathwayBrowser/#/R-DRE-5695964 ABHD14B hydrolyses PNPB IEA Danio rerio 16836 R-GGA-176646 https://reactome.org/PathwayBrowser/#/R-GGA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Gallus gallus 16836 R-GGA-5695964 https://reactome.org/PathwayBrowser/#/R-GGA-5695964 ABHD14B hydrolyses PNPB IEA Gallus gallus 16836 R-HSA-176646 https://reactome.org/PathwayBrowser/#/R-HSA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP TAS Homo sapiens 16836 R-HSA-5695964 https://reactome.org/PathwayBrowser/#/R-HSA-5695964 ABHD14B hydrolyses PNPB TAS Homo sapiens 16836 R-MMU-176646 https://reactome.org/PathwayBrowser/#/R-MMU-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Mus musculus 16836 R-MMU-5695964 https://reactome.org/PathwayBrowser/#/R-MMU-5695964 ABHD14B hydrolyses PNPB IEA Mus musculus 16836 R-RNO-176646 https://reactome.org/PathwayBrowser/#/R-RNO-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Rattus norvegicus 16836 R-RNO-5695964 https://reactome.org/PathwayBrowser/#/R-RNO-5695964 ABHD14B hydrolyses PNPB IEA Rattus norvegicus 16836 R-SSC-176646 https://reactome.org/PathwayBrowser/#/R-SSC-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Sus scrofa 16836 R-SSC-5695964 https://reactome.org/PathwayBrowser/#/R-SSC-5695964 ABHD14B hydrolyses PNPB IEA Sus scrofa 16836 R-XTR-176646 https://reactome.org/PathwayBrowser/#/R-XTR-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Xenopus tropicalis 16836 R-XTR-5695964 https://reactome.org/PathwayBrowser/#/R-XTR-5695964 ABHD14B hydrolyses PNPB IEA Xenopus tropicalis 16842 R-BTA-2172678 https://reactome.org/PathwayBrowser/#/R-BTA-2172678 PHF8 demethylates histone H4K20me1 IEA Bos taurus 16842 R-BTA-3214912 https://reactome.org/PathwayBrowser/#/R-BTA-3214912 KDM1A, KDM1B demethylate MeK5-histone H3 IEA Bos taurus 16842 R-BTA-4722133 https://reactome.org/PathwayBrowser/#/R-BTA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Bos taurus 16842 R-BTA-4724279 https://reactome.org/PathwayBrowser/#/R-BTA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Bos taurus 16842 R-BTA-4724284 https://reactome.org/PathwayBrowser/#/R-BTA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Bos taurus 16842 R-BTA-4754176 https://reactome.org/PathwayBrowser/#/R-BTA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Bos taurus 16842 R-BTA-4754181 https://reactome.org/PathwayBrowser/#/R-BTA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Bos taurus 16842 R-BTA-4754187 https://reactome.org/PathwayBrowser/#/R-BTA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Bos taurus 16842 R-BTA-5423117 https://reactome.org/PathwayBrowser/#/R-BTA-5423117 PHF8 demethylates MeK21-histone H4 IEA Bos taurus 16842 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 16842 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 16842 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 16842 R-BTA-5661114 https://reactome.org/PathwayBrowser/#/R-BTA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Bos taurus 16842 R-BTA-5661115 https://reactome.org/PathwayBrowser/#/R-BTA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Bos taurus 16842 R-BTA-5661116 https://reactome.org/PathwayBrowser/#/R-BTA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Bos taurus 16842 R-BTA-5661120 https://reactome.org/PathwayBrowser/#/R-BTA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Bos taurus 16842 R-BTA-5661121 https://reactome.org/PathwayBrowser/#/R-BTA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Bos taurus 16842 R-BTA-5661122 https://reactome.org/PathwayBrowser/#/R-BTA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Bos taurus 16842 R-BTA-5661123 https://reactome.org/PathwayBrowser/#/R-BTA-5661123 KDM1A, KDM1B demethylate Me2K5-histone H3 IEA Bos taurus 16842 R-BTA-5661124 https://reactome.org/PathwayBrowser/#/R-BTA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Bos taurus 16842 R-BTA-5661125 https://reactome.org/PathwayBrowser/#/R-BTA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Bos taurus 16842 R-BTA-6797653 https://reactome.org/PathwayBrowser/#/R-BTA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Bos taurus 16842 R-BTA-6797913 https://reactome.org/PathwayBrowser/#/R-BTA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Bos taurus 16842 R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 16842 R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 16842 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 16842 R-BTA-8857692 https://reactome.org/PathwayBrowser/#/R-BTA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Bos taurus 16842 R-CEL-2172678 https://reactome.org/PathwayBrowser/#/R-CEL-2172678 PHF8 demethylates histone H4K20me1 IEA Caenorhabditis elegans 16842 R-CEL-3214912 https://reactome.org/PathwayBrowser/#/R-CEL-3214912 KDM1A, KDM1B demethylate MeK5-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-4722133 https://reactome.org/PathwayBrowser/#/R-CEL-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-4724279 https://reactome.org/PathwayBrowser/#/R-CEL-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-4724284 https://reactome.org/PathwayBrowser/#/R-CEL-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-4754176 https://reactome.org/PathwayBrowser/#/R-CEL-4754176 JMJD6 demethylates MeR3-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-4754181 https://reactome.org/PathwayBrowser/#/R-CEL-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-4754187 https://reactome.org/PathwayBrowser/#/R-CEL-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-5423117 https://reactome.org/PathwayBrowser/#/R-CEL-5423117 PHF8 demethylates MeK21-histone H4 IEA Caenorhabditis elegans 16842 R-CEL-5661114 https://reactome.org/PathwayBrowser/#/R-CEL-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-5661115 https://reactome.org/PathwayBrowser/#/R-CEL-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-5661116 https://reactome.org/PathwayBrowser/#/R-CEL-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-5661120 https://reactome.org/PathwayBrowser/#/R-CEL-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-5661121 https://reactome.org/PathwayBrowser/#/R-CEL-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-5661122 https://reactome.org/PathwayBrowser/#/R-CEL-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-5661123 https://reactome.org/PathwayBrowser/#/R-CEL-5661123 KDM1A, KDM1B demethylate Me2K5-histone H3 IEA Caenorhabditis elegans 16842 R-CEL-5661124 https://reactome.org/PathwayBrowser/#/R-CEL-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Caenorhabditis elegans 16842 R-CEL-5661125 https://reactome.org/PathwayBrowser/#/R-CEL-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Caenorhabditis elegans 16842 R-CEL-6797653 https://reactome.org/PathwayBrowser/#/R-CEL-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Caenorhabditis elegans 16842 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 16842 R-CFA-2172678 https://reactome.org/PathwayBrowser/#/R-CFA-2172678 PHF8 demethylates histone H4K20me1 IEA Canis familiaris 16842 R-CFA-3214912 https://reactome.org/PathwayBrowser/#/R-CFA-3214912 KDM1A, KDM1B demethylate MeK5-histone H3 IEA Canis familiaris 16842 R-CFA-4722133 https://reactome.org/PathwayBrowser/#/R-CFA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Canis familiaris 16842 R-CFA-4724279 https://reactome.org/PathwayBrowser/#/R-CFA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Canis familiaris 16842 R-CFA-4724284 https://reactome.org/PathwayBrowser/#/R-CFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Canis familiaris 16842 R-CFA-4754176 https://reactome.org/PathwayBrowser/#/R-CFA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Canis familiaris 16842 R-CFA-4754181 https://reactome.org/PathwayBrowser/#/R-CFA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Canis familiaris 16842 R-CFA-4754187 https://reactome.org/PathwayBrowser/#/R-CFA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Canis familiaris 16842 R-CFA-5423117 https://reactome.org/PathwayBrowser/#/R-CFA-5423117 PHF8 demethylates MeK21-histone H4 IEA Canis familiaris 16842 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 16842 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 16842 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 16842 R-CFA-5661114 https://reactome.org/PathwayBrowser/#/R-CFA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Canis familiaris 16842 R-CFA-5661115 https://reactome.org/PathwayBrowser/#/R-CFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Canis familiaris 16842 R-CFA-5661116 https://reactome.org/PathwayBrowser/#/R-CFA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Canis familiaris 16842 R-CFA-5661120 https://reactome.org/PathwayBrowser/#/R-CFA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Canis familiaris 16842 R-CFA-5661121 https://reactome.org/PathwayBrowser/#/R-CFA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Canis familiaris 16842 R-CFA-5661122 https://reactome.org/PathwayBrowser/#/R-CFA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Canis familiaris 16842 R-CFA-5661123 https://reactome.org/PathwayBrowser/#/R-CFA-5661123 KDM1A, KDM1B demethylate Me2K5-histone H3 IEA Canis familiaris 16842 R-CFA-5661124 https://reactome.org/PathwayBrowser/#/R-CFA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Canis familiaris 16842 R-CFA-5661125 https://reactome.org/PathwayBrowser/#/R-CFA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Canis familiaris 16842 R-CFA-6797653 https://reactome.org/PathwayBrowser/#/R-CFA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Canis familiaris 16842 R-CFA-6797913 https://reactome.org/PathwayBrowser/#/R-CFA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Canis familiaris 16842 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 16842 R-CFA-8857692 https://reactome.org/PathwayBrowser/#/R-CFA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Canis familiaris 16842 R-DDI-2172678 https://reactome.org/PathwayBrowser/#/R-DDI-2172678 PHF8 demethylates histone H4K20me1 IEA Dictyostelium discoideum 16842 R-DDI-4754181 https://reactome.org/PathwayBrowser/#/R-DDI-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Dictyostelium discoideum 16842 R-DDI-4754187 https://reactome.org/PathwayBrowser/#/R-DDI-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Dictyostelium discoideum 16842 R-DDI-5661116 https://reactome.org/PathwayBrowser/#/R-DDI-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Dictyostelium discoideum 16842 R-DDI-5661121 https://reactome.org/PathwayBrowser/#/R-DDI-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Dictyostelium discoideum 16842 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 16842 R-DME-2172678 https://reactome.org/PathwayBrowser/#/R-DME-2172678 PHF8 demethylates histone H4K20me1 IEA Drosophila melanogaster 16842 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 16842 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 16842 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 16842 R-DME-5661124 https://reactome.org/PathwayBrowser/#/R-DME-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Drosophila melanogaster 16842 R-DME-5661125 https://reactome.org/PathwayBrowser/#/R-DME-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Drosophila melanogaster 16842 R-DME-6797913 https://reactome.org/PathwayBrowser/#/R-DME-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Drosophila melanogaster 16842 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 16842 R-DRE-2172678 https://reactome.org/PathwayBrowser/#/R-DRE-2172678 PHF8 demethylates histone H4K20me1 IEA Danio rerio 16842 R-DRE-5423117 https://reactome.org/PathwayBrowser/#/R-DRE-5423117 PHF8 demethylates MeK21-histone H4 IEA Danio rerio 16842 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 16842 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 16842 R-DRE-5661124 https://reactome.org/PathwayBrowser/#/R-DRE-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Danio rerio 16842 R-DRE-5661125 https://reactome.org/PathwayBrowser/#/R-DRE-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Danio rerio 16842 R-DRE-6797913 https://reactome.org/PathwayBrowser/#/R-DRE-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Danio rerio 16842 R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 16842 R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 16842 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 16842 R-DRE-8857692 https://reactome.org/PathwayBrowser/#/R-DRE-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Danio rerio 16842 R-GGA-2172678 https://reactome.org/PathwayBrowser/#/R-GGA-2172678 PHF8 demethylates histone H4K20me1 IEA Gallus gallus 16842 R-GGA-353356 https://reactome.org/PathwayBrowser/#/R-GGA-353356 Reversal of Alkylation Damage By DNA Dioxygenases TAS Gallus gallus 16842 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 16842 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 16842 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 16842 R-GGA-5661124 https://reactome.org/PathwayBrowser/#/R-GGA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Gallus gallus 16842 R-GGA-5661125 https://reactome.org/PathwayBrowser/#/R-GGA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Gallus gallus 16842 R-GGA-6797653 https://reactome.org/PathwayBrowser/#/R-GGA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Gallus gallus 16842 R-GGA-6797913 https://reactome.org/PathwayBrowser/#/R-GGA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Gallus gallus 16842 R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 16842 R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 16842 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 16842 R-GGA-8857692 https://reactome.org/PathwayBrowser/#/R-GGA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Gallus gallus 16842 R-HSA-112118 https://reactome.org/PathwayBrowser/#/R-HSA-112118 Oxidative demethylation of 1-meA damaged DNA by ALKBH2 TAS Homo sapiens 16842 R-HSA-112120 https://reactome.org/PathwayBrowser/#/R-HSA-112120 Oxidative demethylation of 3-meC damaged DNA by ALKBH2 TAS Homo sapiens 16842 R-HSA-112123 https://reactome.org/PathwayBrowser/#/R-HSA-112123 Oxidative demethylation of 1-meA damaged DNA By ALKBH3 TAS Homo sapiens 16842 R-HSA-112124 https://reactome.org/PathwayBrowser/#/R-HSA-112124 Oxidative demethylation of 3-meC damaged DNA By ALKBH3 TAS Homo sapiens 16842 R-HSA-2172678 https://reactome.org/PathwayBrowser/#/R-HSA-2172678 PHF8 demethylates histone H4K20me1 TAS Homo sapiens 16842 R-HSA-3214912 https://reactome.org/PathwayBrowser/#/R-HSA-3214912 KDM1A, KDM1B demethylate MeK5-histone H3 TAS Homo sapiens 16842 R-HSA-4722133 https://reactome.org/PathwayBrowser/#/R-HSA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 TAS Homo sapiens 16842 R-HSA-4724279 https://reactome.org/PathwayBrowser/#/R-HSA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 TAS Homo sapiens 16842 R-HSA-4724284 https://reactome.org/PathwayBrowser/#/R-HSA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 TAS Homo sapiens 16842 R-HSA-4754176 https://reactome.org/PathwayBrowser/#/R-HSA-4754176 JMJD6 demethylates MeR3-histone H3 TAS Homo sapiens 16842 R-HSA-4754181 https://reactome.org/PathwayBrowser/#/R-HSA-4754181 KDM5A-D demethylate Me2K5-histone H3 TAS Homo sapiens 16842 R-HSA-4754187 https://reactome.org/PathwayBrowser/#/R-HSA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 TAS Homo sapiens 16842 R-HSA-5423117 https://reactome.org/PathwayBrowser/#/R-HSA-5423117 PHF8 demethylates MeK21-histone H4 TAS Homo sapiens 16842 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 16842 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 16842 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 16842 R-HSA-5661114 https://reactome.org/PathwayBrowser/#/R-HSA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 TAS Homo sapiens 16842 R-HSA-5661115 https://reactome.org/PathwayBrowser/#/R-HSA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 TAS Homo sapiens 16842 R-HSA-5661116 https://reactome.org/PathwayBrowser/#/R-HSA-5661116 KDM5A-D demethylate Me3K5-histone H3 TAS Homo sapiens 16842 R-HSA-5661120 https://reactome.org/PathwayBrowser/#/R-HSA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 TAS Homo sapiens 16842 R-HSA-5661121 https://reactome.org/PathwayBrowser/#/R-HSA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 TAS Homo sapiens 16842 R-HSA-5661122 https://reactome.org/PathwayBrowser/#/R-HSA-5661122 JMJD6 demethylates Me2R3-histone H3 TAS Homo sapiens 16842 R-HSA-5661123 https://reactome.org/PathwayBrowser/#/R-HSA-5661123 KDM1A, KDM1B demethylate Me2K5-histone H3 TAS Homo sapiens 16842 R-HSA-5661124 https://reactome.org/PathwayBrowser/#/R-HSA-5661124 JMJD6 demethylates MeR4-HIST1H4 TAS Homo sapiens 16842 R-HSA-5661125 https://reactome.org/PathwayBrowser/#/R-HSA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 TAS Homo sapiens 16842 R-HSA-6797653 https://reactome.org/PathwayBrowser/#/R-HSA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC TAS Homo sapiens 16842 R-HSA-6797913 https://reactome.org/PathwayBrowser/#/R-HSA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly TAS Homo sapiens 16842 R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 16842 R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 16842 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 16842 R-HSA-8857692 https://reactome.org/PathwayBrowser/#/R-HSA-8857692 RNA demethylases demethylate N6-methyladenosine RNA TAS Homo sapiens 16842 R-HSA-9822461 https://reactome.org/PathwayBrowser/#/R-HSA-9822461 KDM5B demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 16842 R-HSA-9822467 https://reactome.org/PathwayBrowser/#/R-HSA-9822467 KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 16842 R-HSA-9822914 https://reactome.org/PathwayBrowser/#/R-HSA-9822914 KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 16842 R-HSA-9822985 https://reactome.org/PathwayBrowser/#/R-HSA-9822985 KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 16842 R-MMU-3214912 https://reactome.org/PathwayBrowser/#/R-MMU-3214912 KDM1A, KDM1B demethylate MeK5-histone H3 IEA Mus musculus 16842 R-MMU-4722133 https://reactome.org/PathwayBrowser/#/R-MMU-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Mus musculus 16842 R-MMU-4724279 https://reactome.org/PathwayBrowser/#/R-MMU-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Mus musculus 16842 R-MMU-4724284 https://reactome.org/PathwayBrowser/#/R-MMU-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Mus musculus 16842 R-MMU-4754176 https://reactome.org/PathwayBrowser/#/R-MMU-4754176 JMJD6 demethylates MeR3-histone H3 IEA Mus musculus 16842 R-MMU-4754181 https://reactome.org/PathwayBrowser/#/R-MMU-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Mus musculus 16842 R-MMU-4754187 https://reactome.org/PathwayBrowser/#/R-MMU-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Mus musculus 16842 R-MMU-5423117 https://reactome.org/PathwayBrowser/#/R-MMU-5423117 PHF8 demethylates MeK21-histone H4 IEA Mus musculus 16842 R-MMU-5661114 https://reactome.org/PathwayBrowser/#/R-MMU-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Mus musculus 16842 R-MMU-5661115 https://reactome.org/PathwayBrowser/#/R-MMU-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Mus musculus 16842 R-MMU-5661116 https://reactome.org/PathwayBrowser/#/R-MMU-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Mus musculus 16842 R-MMU-5661120 https://reactome.org/PathwayBrowser/#/R-MMU-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Mus musculus 16842 R-MMU-5661121 https://reactome.org/PathwayBrowser/#/R-MMU-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Mus musculus 16842 R-MMU-5661122 https://reactome.org/PathwayBrowser/#/R-MMU-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Mus musculus 16842 R-MMU-5661123 https://reactome.org/PathwayBrowser/#/R-MMU-5661123 KDM1A, KDM1B demethylate Me2K5-histone H3 IEA Mus musculus 16842 R-MMU-5661124 https://reactome.org/PathwayBrowser/#/R-MMU-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Mus musculus 16842 R-MMU-5661125 https://reactome.org/PathwayBrowser/#/R-MMU-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Mus musculus 16842 R-MMU-6797653 https://reactome.org/PathwayBrowser/#/R-MMU-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Mus musculus 16842 R-MMU-6797913 https://reactome.org/PathwayBrowser/#/R-MMU-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Mus musculus 16842 R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 16842 R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 16842 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 16842 R-MMU-8857692 https://reactome.org/PathwayBrowser/#/R-MMU-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Mus musculus 16842 R-MMU-9822448 https://reactome.org/PathwayBrowser/#/R-MMU-9822448 Kdm5b demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 16842 R-MMU-9822463 https://reactome.org/PathwayBrowser/#/R-MMU-9822463 Kdm5a demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 16842 R-MMU-9822924 https://reactome.org/PathwayBrowser/#/R-MMU-9822924 Kdm6b (Jmjd3) demethylates histone H3 trimethyllysine-27 (H3K27me3) TAS Mus musculus 16842 R-MMU-9822964 https://reactome.org/PathwayBrowser/#/R-MMU-9822964 Kdm6a (Utx) demethylates trimethylated histone H3 lysine-27 (H3K27me3) TAS Mus musculus 16842 R-MTU-879245 https://reactome.org/PathwayBrowser/#/R-MTU-879245 mycothiol binds formaldehyde and is dehydrogenated TAS Mycobacterium tuberculosis 16842 R-PFA-2172678 https://reactome.org/PathwayBrowser/#/R-PFA-2172678 PHF8 demethylates histone H4K20me1 IEA Plasmodium falciparum 16842 R-PFA-4724284 https://reactome.org/PathwayBrowser/#/R-PFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Plasmodium falciparum 16842 R-PFA-5661115 https://reactome.org/PathwayBrowser/#/R-PFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Plasmodium falciparum 16842 R-RNO-2172678 https://reactome.org/PathwayBrowser/#/R-RNO-2172678 PHF8 demethylates histone H4K20me1 IEA Rattus norvegicus 16842 R-RNO-3214912 https://reactome.org/PathwayBrowser/#/R-RNO-3214912 KDM1A, KDM1B demethylate MeK5-histone H3 IEA Rattus norvegicus 16842 R-RNO-4722133 https://reactome.org/PathwayBrowser/#/R-RNO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Rattus norvegicus 16842 R-RNO-4724279 https://reactome.org/PathwayBrowser/#/R-RNO-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Rattus norvegicus 16842 R-RNO-4724284 https://reactome.org/PathwayBrowser/#/R-RNO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Rattus norvegicus 16842 R-RNO-4754176 https://reactome.org/PathwayBrowser/#/R-RNO-4754176 JMJD6 demethylates MeR3-histone H3 IEA Rattus norvegicus 16842 R-RNO-4754181 https://reactome.org/PathwayBrowser/#/R-RNO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Rattus norvegicus 16842 R-RNO-4754187 https://reactome.org/PathwayBrowser/#/R-RNO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Rattus norvegicus 16842 R-RNO-5423117 https://reactome.org/PathwayBrowser/#/R-RNO-5423117 PHF8 demethylates MeK21-histone H4 IEA Rattus norvegicus 16842 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 16842 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 16842 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 16842 R-RNO-5661114 https://reactome.org/PathwayBrowser/#/R-RNO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Rattus norvegicus 16842 R-RNO-5661115 https://reactome.org/PathwayBrowser/#/R-RNO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Rattus norvegicus 16842 R-RNO-5661116 https://reactome.org/PathwayBrowser/#/R-RNO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Rattus norvegicus 16842 R-RNO-5661120 https://reactome.org/PathwayBrowser/#/R-RNO-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Rattus norvegicus 16842 R-RNO-5661121 https://reactome.org/PathwayBrowser/#/R-RNO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Rattus norvegicus 16842 R-RNO-5661122 https://reactome.org/PathwayBrowser/#/R-RNO-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Rattus norvegicus 16842 R-RNO-5661123 https://reactome.org/PathwayBrowser/#/R-RNO-5661123 KDM1A, KDM1B demethylate Me2K5-histone H3 IEA Rattus norvegicus 16842 R-RNO-5661124 https://reactome.org/PathwayBrowser/#/R-RNO-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Rattus norvegicus 16842 R-RNO-5661125 https://reactome.org/PathwayBrowser/#/R-RNO-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Rattus norvegicus 16842 R-RNO-6797653 https://reactome.org/PathwayBrowser/#/R-RNO-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Rattus norvegicus 16842 R-RNO-6797913 https://reactome.org/PathwayBrowser/#/R-RNO-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Rattus norvegicus 16842 R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 16842 R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 16842 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 16842 R-RNO-8857692 https://reactome.org/PathwayBrowser/#/R-RNO-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Rattus norvegicus 16842 R-SCE-2172678 https://reactome.org/PathwayBrowser/#/R-SCE-2172678 PHF8 demethylates histone H4K20me1 IEA Saccharomyces cerevisiae 16842 R-SCE-3214912 https://reactome.org/PathwayBrowser/#/R-SCE-3214912 KDM1A, KDM1B demethylate MeK5-histone H3 IEA Saccharomyces cerevisiae 16842 R-SCE-4722133 https://reactome.org/PathwayBrowser/#/R-SCE-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Saccharomyces cerevisiae 16842 R-SCE-4724279 https://reactome.org/PathwayBrowser/#/R-SCE-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Saccharomyces cerevisiae 16842 R-SCE-4754181 https://reactome.org/PathwayBrowser/#/R-SCE-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Saccharomyces cerevisiae 16842 R-SCE-4754187 https://reactome.org/PathwayBrowser/#/R-SCE-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Saccharomyces cerevisiae 16842 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16842 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16842 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 16842 R-SCE-5661114 https://reactome.org/PathwayBrowser/#/R-SCE-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Saccharomyces cerevisiae 16842 R-SCE-5661116 https://reactome.org/PathwayBrowser/#/R-SCE-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Saccharomyces cerevisiae 16842 R-SCE-5661120 https://reactome.org/PathwayBrowser/#/R-SCE-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Saccharomyces cerevisiae 16842 R-SCE-5661121 https://reactome.org/PathwayBrowser/#/R-SCE-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Saccharomyces cerevisiae 16842 R-SCE-5661123 https://reactome.org/PathwayBrowser/#/R-SCE-5661123 KDM1A, KDM1B demethylate Me2K5-histone H3 IEA Saccharomyces cerevisiae 16842 R-SPO-2172678 https://reactome.org/PathwayBrowser/#/R-SPO-2172678 PHF8 demethylates histone H4K20me1 IEA Schizosaccharomyces pombe 16842 R-SPO-3214912 https://reactome.org/PathwayBrowser/#/R-SPO-3214912 KDM1A, KDM1B demethylate MeK5-histone H3 IEA Schizosaccharomyces pombe 16842 R-SPO-4722133 https://reactome.org/PathwayBrowser/#/R-SPO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Schizosaccharomyces pombe 16842 R-SPO-4724284 https://reactome.org/PathwayBrowser/#/R-SPO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Schizosaccharomyces pombe 16842 R-SPO-4754181 https://reactome.org/PathwayBrowser/#/R-SPO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Schizosaccharomyces pombe 16842 R-SPO-4754187 https://reactome.org/PathwayBrowser/#/R-SPO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Schizosaccharomyces pombe 16842 R-SPO-5423117 https://reactome.org/PathwayBrowser/#/R-SPO-5423117 PHF8 demethylates MeK21-histone H4 IEA Schizosaccharomyces pombe 16842 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16842 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 16842 R-SPO-5661114 https://reactome.org/PathwayBrowser/#/R-SPO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Schizosaccharomyces pombe 16842 R-SPO-5661115 https://reactome.org/PathwayBrowser/#/R-SPO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Schizosaccharomyces pombe 16842 R-SPO-5661116 https://reactome.org/PathwayBrowser/#/R-SPO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Schizosaccharomyces pombe 16842 R-SPO-5661121 https://reactome.org/PathwayBrowser/#/R-SPO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Schizosaccharomyces pombe 16842 R-SPO-5661123 https://reactome.org/PathwayBrowser/#/R-SPO-5661123 KDM1A, KDM1B demethylate Me2K5-histone H3 IEA Schizosaccharomyces pombe 16842 R-SSC-2172678 https://reactome.org/PathwayBrowser/#/R-SSC-2172678 PHF8 demethylates histone H4K20me1 IEA Sus scrofa 16842 R-SSC-3214912 https://reactome.org/PathwayBrowser/#/R-SSC-3214912 KDM1A, KDM1B demethylate MeK5-histone H3 IEA Sus scrofa 16842 R-SSC-4722133 https://reactome.org/PathwayBrowser/#/R-SSC-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Sus scrofa 16842 R-SSC-4724279 https://reactome.org/PathwayBrowser/#/R-SSC-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Sus scrofa 16842 R-SSC-4724284 https://reactome.org/PathwayBrowser/#/R-SSC-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Sus scrofa 16842 R-SSC-4754176 https://reactome.org/PathwayBrowser/#/R-SSC-4754176 JMJD6 demethylates MeR3-histone H3 IEA Sus scrofa 16842 R-SSC-4754181 https://reactome.org/PathwayBrowser/#/R-SSC-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Sus scrofa 16842 R-SSC-4754187 https://reactome.org/PathwayBrowser/#/R-SSC-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Sus scrofa 16842 R-SSC-5423117 https://reactome.org/PathwayBrowser/#/R-SSC-5423117 PHF8 demethylates MeK21-histone H4 IEA Sus scrofa 16842 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 16842 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 16842 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 16842 R-SSC-5661114 https://reactome.org/PathwayBrowser/#/R-SSC-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Sus scrofa 16842 R-SSC-5661115 https://reactome.org/PathwayBrowser/#/R-SSC-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Sus scrofa 16842 R-SSC-5661116 https://reactome.org/PathwayBrowser/#/R-SSC-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Sus scrofa 16842 R-SSC-5661120 https://reactome.org/PathwayBrowser/#/R-SSC-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Sus scrofa 16842 R-SSC-5661121 https://reactome.org/PathwayBrowser/#/R-SSC-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Sus scrofa 16842 R-SSC-5661122 https://reactome.org/PathwayBrowser/#/R-SSC-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Sus scrofa 16842 R-SSC-5661123 https://reactome.org/PathwayBrowser/#/R-SSC-5661123 KDM1A, KDM1B demethylate Me2K5-histone H3 IEA Sus scrofa 16842 R-SSC-5661124 https://reactome.org/PathwayBrowser/#/R-SSC-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Sus scrofa 16842 R-SSC-5661125 https://reactome.org/PathwayBrowser/#/R-SSC-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Sus scrofa 16842 R-SSC-6797653 https://reactome.org/PathwayBrowser/#/R-SSC-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Sus scrofa 16842 R-SSC-6797913 https://reactome.org/PathwayBrowser/#/R-SSC-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Sus scrofa 16842 R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 16842 R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 16842 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 16842 R-SSC-8857692 https://reactome.org/PathwayBrowser/#/R-SSC-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Sus scrofa 16842 R-XTR-2172678 https://reactome.org/PathwayBrowser/#/R-XTR-2172678 PHF8 demethylates histone H4K20me1 IEA Xenopus tropicalis 16842 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 16842 R-XTR-8857692 https://reactome.org/PathwayBrowser/#/R-XTR-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Xenopus tropicalis 16846 R-HSA-9683760 https://reactome.org/PathwayBrowser/#/R-HSA-9683760 GalNAc is transferred onto 3a TAS Homo sapiens 16846 R-HSA-9694438 https://reactome.org/PathwayBrowser/#/R-HSA-9694438 GalNAc is transferred onto 3a IEA Homo sapiens 16852 R-BTA-5662662 https://reactome.org/PathwayBrowser/#/R-BTA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Bos taurus 16852 R-BTA-5662692 https://reactome.org/PathwayBrowser/#/R-BTA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Bos taurus 16852 R-BTA-5663050 https://reactome.org/PathwayBrowser/#/R-BTA-5663050 DHI and DHICA polymerize forming eumelanin IEA Bos taurus 16852 R-CEL-5662662 https://reactome.org/PathwayBrowser/#/R-CEL-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Caenorhabditis elegans 16852 R-CEL-5662692 https://reactome.org/PathwayBrowser/#/R-CEL-5662692 Dopa is oxidized to dopaquinone by TYR IEA Caenorhabditis elegans 16852 R-CEL-5663050 https://reactome.org/PathwayBrowser/#/R-CEL-5663050 DHI and DHICA polymerize forming eumelanin IEA Caenorhabditis elegans 16852 R-CFA-5662662 https://reactome.org/PathwayBrowser/#/R-CFA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Canis familiaris 16852 R-CFA-5662692 https://reactome.org/PathwayBrowser/#/R-CFA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Canis familiaris 16852 R-CFA-5663050 https://reactome.org/PathwayBrowser/#/R-CFA-5663050 DHI and DHICA polymerize forming eumelanin IEA Canis familiaris 16852 R-DDI-5662662 https://reactome.org/PathwayBrowser/#/R-DDI-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Dictyostelium discoideum 16852 R-DDI-5662692 https://reactome.org/PathwayBrowser/#/R-DDI-5662692 Dopa is oxidized to dopaquinone by TYR IEA Dictyostelium discoideum 16852 R-DDI-5663050 https://reactome.org/PathwayBrowser/#/R-DDI-5663050 DHI and DHICA polymerize forming eumelanin IEA Dictyostelium discoideum 16852 R-GGA-5662662 https://reactome.org/PathwayBrowser/#/R-GGA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Gallus gallus 16852 R-GGA-5662692 https://reactome.org/PathwayBrowser/#/R-GGA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Gallus gallus 16852 R-GGA-5663050 https://reactome.org/PathwayBrowser/#/R-GGA-5663050 DHI and DHICA polymerize forming eumelanin IEA Gallus gallus 16852 R-HSA-5662662 https://reactome.org/PathwayBrowser/#/R-HSA-5662662 Tyrosinase oxidises tyrosine to dopaquinone TAS Homo sapiens 16852 R-HSA-5662669 https://reactome.org/PathwayBrowser/#/R-HSA-5662669 Dopaquinone transforms to Leucodopachrome (Cyclodopa) TAS Homo sapiens 16852 R-HSA-5662692 https://reactome.org/PathwayBrowser/#/R-HSA-5662692 Dopa is oxidized to dopaquinone by TYR TAS Homo sapiens 16852 R-HSA-5662904 https://reactome.org/PathwayBrowser/#/R-HSA-5662904 CD isomers transform to BT, BTCA, BZ, ODHBT TAS Homo sapiens 16852 R-HSA-5662908 https://reactome.org/PathwayBrowser/#/R-HSA-5662908 Dopaquinone, cysteine form CD isomers TAS Homo sapiens 16852 R-HSA-5663050 https://reactome.org/PathwayBrowser/#/R-HSA-5663050 DHI and DHICA polymerize forming eumelanin TAS Homo sapiens 16852 R-HSA-5672019 https://reactome.org/PathwayBrowser/#/R-HSA-5672019 Leucodopachrome, L-Dopaquinone transform to Dopachrome, L-Dopa TAS Homo sapiens 16852 R-MMU-5662662 https://reactome.org/PathwayBrowser/#/R-MMU-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Mus musculus 16852 R-MMU-5662692 https://reactome.org/PathwayBrowser/#/R-MMU-5662692 Dopa is oxidized to dopaquinone by TYR IEA Mus musculus 16852 R-MMU-5663050 https://reactome.org/PathwayBrowser/#/R-MMU-5663050 DHI and DHICA polymerize forming eumelanin IEA Mus musculus 16852 R-RNO-5662662 https://reactome.org/PathwayBrowser/#/R-RNO-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Rattus norvegicus 16852 R-RNO-5662692 https://reactome.org/PathwayBrowser/#/R-RNO-5662692 Dopa is oxidized to dopaquinone by TYR IEA Rattus norvegicus 16852 R-RNO-5663050 https://reactome.org/PathwayBrowser/#/R-RNO-5663050 DHI and DHICA polymerize forming eumelanin IEA Rattus norvegicus 16852 R-SSC-5662662 https://reactome.org/PathwayBrowser/#/R-SSC-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Sus scrofa 16852 R-SSC-5662692 https://reactome.org/PathwayBrowser/#/R-SSC-5662692 Dopa is oxidized to dopaquinone by TYR IEA Sus scrofa 16852 R-SSC-5663050 https://reactome.org/PathwayBrowser/#/R-SSC-5663050 DHI and DHICA polymerize forming eumelanin IEA Sus scrofa 16852 R-XTR-5662662 https://reactome.org/PathwayBrowser/#/R-XTR-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Xenopus tropicalis 16852 R-XTR-5662692 https://reactome.org/PathwayBrowser/#/R-XTR-5662692 Dopa is oxidized to dopaquinone by TYR IEA Xenopus tropicalis 16852 R-XTR-5663050 https://reactome.org/PathwayBrowser/#/R-XTR-5663050 DHI and DHICA polymerize forming eumelanin IEA Xenopus tropicalis 16856 R-BTA-1655879 https://reactome.org/PathwayBrowser/#/R-BTA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Bos taurus 16856 R-BTA-176059 https://reactome.org/PathwayBrowser/#/R-BTA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Bos taurus 16856 R-BTA-2161660 https://reactome.org/PathwayBrowser/#/R-BTA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Bos taurus 16856 R-BTA-3301943 https://reactome.org/PathwayBrowser/#/R-BTA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Bos taurus 16856 R-BTA-3323013 https://reactome.org/PathwayBrowser/#/R-BTA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 16856 R-BTA-3323079 https://reactome.org/PathwayBrowser/#/R-BTA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 16856 R-BTA-3341397 https://reactome.org/PathwayBrowser/#/R-BTA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 16856 R-BTA-5693724 https://reactome.org/PathwayBrowser/#/R-BTA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Bos taurus 16856 R-BTA-6799695 https://reactome.org/PathwayBrowser/#/R-BTA-6799695 GPX5,6 reduce H2O2 to H2O IEA Bos taurus 16856 R-BTA-8943279 https://reactome.org/PathwayBrowser/#/R-BTA-8943279 GGT dimers hydrolyse GSH IEA Bos taurus 16856 R-BTA-9011595 https://reactome.org/PathwayBrowser/#/R-BTA-9011595 GSTZ1 dimer dehalogenates DCA IEA Bos taurus 16856 R-CEL-3301943 https://reactome.org/PathwayBrowser/#/R-CEL-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Caenorhabditis elegans 16856 R-CEL-3323079 https://reactome.org/PathwayBrowser/#/R-CEL-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 16856 R-CEL-3341397 https://reactome.org/PathwayBrowser/#/R-CEL-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Caenorhabditis elegans 16856 R-CEL-5693724 https://reactome.org/PathwayBrowser/#/R-CEL-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Caenorhabditis elegans 16856 R-CEL-6799695 https://reactome.org/PathwayBrowser/#/R-CEL-6799695 GPX5,6 reduce H2O2 to H2O IEA Caenorhabditis elegans 16856 R-CEL-8943279 https://reactome.org/PathwayBrowser/#/R-CEL-8943279 GGT dimers hydrolyse GSH IEA Caenorhabditis elegans 16856 R-CEL-9011595 https://reactome.org/PathwayBrowser/#/R-CEL-9011595 GSTZ1 dimer dehalogenates DCA IEA Caenorhabditis elegans 16856 R-CFA-1655879 https://reactome.org/PathwayBrowser/#/R-CFA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Canis familiaris 16856 R-CFA-176059 https://reactome.org/PathwayBrowser/#/R-CFA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Canis familiaris 16856 R-CFA-2161660 https://reactome.org/PathwayBrowser/#/R-CFA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Canis familiaris 16856 R-CFA-3301943 https://reactome.org/PathwayBrowser/#/R-CFA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Canis familiaris 16856 R-CFA-3323013 https://reactome.org/PathwayBrowser/#/R-CFA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 16856 R-CFA-3323079 https://reactome.org/PathwayBrowser/#/R-CFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 16856 R-CFA-5693724 https://reactome.org/PathwayBrowser/#/R-CFA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Canis familiaris 16856 R-CFA-6799695 https://reactome.org/PathwayBrowser/#/R-CFA-6799695 GPX5,6 reduce H2O2 to H2O IEA Canis familiaris 16856 R-CFA-8943279 https://reactome.org/PathwayBrowser/#/R-CFA-8943279 GGT dimers hydrolyse GSH IEA Canis familiaris 16856 R-CFA-9011595 https://reactome.org/PathwayBrowser/#/R-CFA-9011595 GSTZ1 dimer dehalogenates DCA IEA Canis familiaris 16856 R-DDI-176059 https://reactome.org/PathwayBrowser/#/R-DDI-176059 GST trimers transfer GS from GSH to luminal substrates IEA Dictyostelium discoideum 16856 R-DDI-3323079 https://reactome.org/PathwayBrowser/#/R-DDI-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 16856 R-DDI-5693724 https://reactome.org/PathwayBrowser/#/R-DDI-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Dictyostelium discoideum 16856 R-DDI-9011595 https://reactome.org/PathwayBrowser/#/R-DDI-9011595 GSTZ1 dimer dehalogenates DCA IEA Dictyostelium discoideum 16856 R-DME-176059 https://reactome.org/PathwayBrowser/#/R-DME-176059 GST trimers transfer GS from GSH to luminal substrates IEA Drosophila melanogaster 16856 R-DME-2161660 https://reactome.org/PathwayBrowser/#/R-DME-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Drosophila melanogaster 16856 R-DME-5693724 https://reactome.org/PathwayBrowser/#/R-DME-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Drosophila melanogaster 16856 R-DME-8943279 https://reactome.org/PathwayBrowser/#/R-DME-8943279 GGT dimers hydrolyse GSH IEA Drosophila melanogaster 16856 R-DME-9011595 https://reactome.org/PathwayBrowser/#/R-DME-9011595 GSTZ1 dimer dehalogenates DCA IEA Drosophila melanogaster 16856 R-DRE-176059 https://reactome.org/PathwayBrowser/#/R-DRE-176059 GST trimers transfer GS from GSH to luminal substrates IEA Danio rerio 16856 R-DRE-2161660 https://reactome.org/PathwayBrowser/#/R-DRE-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Danio rerio 16856 R-DRE-3301943 https://reactome.org/PathwayBrowser/#/R-DRE-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Danio rerio 16856 R-DRE-5693724 https://reactome.org/PathwayBrowser/#/R-DRE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Danio rerio 16856 R-DRE-6799695 https://reactome.org/PathwayBrowser/#/R-DRE-6799695 GPX5,6 reduce H2O2 to H2O IEA Danio rerio 16856 R-DRE-9011595 https://reactome.org/PathwayBrowser/#/R-DRE-9011595 GSTZ1 dimer dehalogenates DCA IEA Danio rerio 16856 R-GGA-176059 https://reactome.org/PathwayBrowser/#/R-GGA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Gallus gallus 16856 R-GGA-2161660 https://reactome.org/PathwayBrowser/#/R-GGA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Gallus gallus 16856 R-GGA-3301943 https://reactome.org/PathwayBrowser/#/R-GGA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Gallus gallus 16856 R-GGA-3323079 https://reactome.org/PathwayBrowser/#/R-GGA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 16856 R-GGA-3341397 https://reactome.org/PathwayBrowser/#/R-GGA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Gallus gallus 16856 R-GGA-5693724 https://reactome.org/PathwayBrowser/#/R-GGA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Gallus gallus 16856 R-GGA-8943279 https://reactome.org/PathwayBrowser/#/R-GGA-8943279 GGT dimers hydrolyse GSH IEA Gallus gallus 16856 R-GGA-9011595 https://reactome.org/PathwayBrowser/#/R-GGA-9011595 GSTZ1 dimer dehalogenates DCA IEA Gallus gallus 16856 R-HSA-1247915 https://reactome.org/PathwayBrowser/#/R-HSA-1247915 GSH translocates from cytosol to extracellular region TAS Homo sapiens 16856 R-HSA-1500817 https://reactome.org/PathwayBrowser/#/R-HSA-1500817 Glutathione is taken up by the bacterium TAS Homo sapiens 16856 R-HSA-1655879 https://reactome.org/PathwayBrowser/#/R-HSA-1655879 Thiosulfate can transfer its sulfur atom to glutathione TAS Homo sapiens 16856 R-HSA-176059 https://reactome.org/PathwayBrowser/#/R-HSA-176059 GST trimers transfer GS from GSH to luminal substrates TAS Homo sapiens 16856 R-HSA-2161660 https://reactome.org/PathwayBrowser/#/R-HSA-2161660 PGH2 is isomerised to PGE2 by PTGES TAS Homo sapiens 16856 R-HSA-3301943 https://reactome.org/PathwayBrowser/#/R-HSA-3301943 GSTK1 dimer transfers GS from GSH to CDNB TAS Homo sapiens 16856 R-HSA-3323013 https://reactome.org/PathwayBrowser/#/R-HSA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 16856 R-HSA-3323079 https://reactome.org/PathwayBrowser/#/R-HSA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 16856 R-HSA-3341397 https://reactome.org/PathwayBrowser/#/R-HSA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 16856 R-HSA-5693724 https://reactome.org/PathwayBrowser/#/R-HSA-5693724 ESD dimer hydrolyses S-FGSH to GSH TAS Homo sapiens 16856 R-HSA-6799695 https://reactome.org/PathwayBrowser/#/R-HSA-6799695 GPX5,6 reduce H2O2 to H2O TAS Homo sapiens 16856 R-HSA-8943279 https://reactome.org/PathwayBrowser/#/R-HSA-8943279 GGT dimers hydrolyse GSH TAS Homo sapiens 16856 R-HSA-9011595 https://reactome.org/PathwayBrowser/#/R-HSA-9011595 GSTZ1 dimer dehalogenates DCA TAS Homo sapiens 16856 R-HSA-9035966 https://reactome.org/PathwayBrowser/#/R-HSA-9035966 Defective GGT1 does not hydrolyse GSH TAS Homo sapiens 16856 R-HSA-9863531 https://reactome.org/PathwayBrowser/#/R-HSA-9863531 GS-MCA spontaneously hydrolyzes TAS Homo sapiens 16856 R-MMU-1655879 https://reactome.org/PathwayBrowser/#/R-MMU-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Mus musculus 16856 R-MMU-176059 https://reactome.org/PathwayBrowser/#/R-MMU-176059 GST trimers transfer GS from GSH to luminal substrates IEA Mus musculus 16856 R-MMU-2161660 https://reactome.org/PathwayBrowser/#/R-MMU-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Mus musculus 16856 R-MMU-3301943 https://reactome.org/PathwayBrowser/#/R-MMU-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Mus musculus 16856 R-MMU-3323013 https://reactome.org/PathwayBrowser/#/R-MMU-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 16856 R-MMU-3323079 https://reactome.org/PathwayBrowser/#/R-MMU-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 16856 R-MMU-3341397 https://reactome.org/PathwayBrowser/#/R-MMU-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 16856 R-MMU-5693724 https://reactome.org/PathwayBrowser/#/R-MMU-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Mus musculus 16856 R-MMU-6799695 https://reactome.org/PathwayBrowser/#/R-MMU-6799695 GPX5,6 reduce H2O2 to H2O IEA Mus musculus 16856 R-MMU-8943279 https://reactome.org/PathwayBrowser/#/R-MMU-8943279 GGT dimers hydrolyse GSH IEA Mus musculus 16856 R-MMU-9011595 https://reactome.org/PathwayBrowser/#/R-MMU-9011595 GSTZ1 dimer dehalogenates DCA IEA Mus musculus 16856 R-PFA-3323079 https://reactome.org/PathwayBrowser/#/R-PFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 16856 R-RNO-1655879 https://reactome.org/PathwayBrowser/#/R-RNO-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Rattus norvegicus 16856 R-RNO-176059 https://reactome.org/PathwayBrowser/#/R-RNO-176059 GST trimers transfer GS from GSH to luminal substrates IEA Rattus norvegicus 16856 R-RNO-2161660 https://reactome.org/PathwayBrowser/#/R-RNO-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Rattus norvegicus 16856 R-RNO-3301943 https://reactome.org/PathwayBrowser/#/R-RNO-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Rattus norvegicus 16856 R-RNO-3323013 https://reactome.org/PathwayBrowser/#/R-RNO-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 16856 R-RNO-3323079 https://reactome.org/PathwayBrowser/#/R-RNO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 16856 R-RNO-3341397 https://reactome.org/PathwayBrowser/#/R-RNO-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 16856 R-RNO-5693724 https://reactome.org/PathwayBrowser/#/R-RNO-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Rattus norvegicus 16856 R-RNO-6799695 https://reactome.org/PathwayBrowser/#/R-RNO-6799695 GPX5,6 reduce H2O2 to H2O IEA Rattus norvegicus 16856 R-RNO-8943279 https://reactome.org/PathwayBrowser/#/R-RNO-8943279 GGT dimers hydrolyse GSH IEA Rattus norvegicus 16856 R-RNO-9011595 https://reactome.org/PathwayBrowser/#/R-RNO-9011595 GSTZ1 dimer dehalogenates DCA IEA Rattus norvegicus 16856 R-SCE-3323079 https://reactome.org/PathwayBrowser/#/R-SCE-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 16856 R-SCE-5693724 https://reactome.org/PathwayBrowser/#/R-SCE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Saccharomyces cerevisiae 16856 R-SCE-8943279 https://reactome.org/PathwayBrowser/#/R-SCE-8943279 GGT dimers hydrolyse GSH IEA Saccharomyces cerevisiae 16856 R-SPO-3323079 https://reactome.org/PathwayBrowser/#/R-SPO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 16856 R-SPO-8943279 https://reactome.org/PathwayBrowser/#/R-SPO-8943279 GGT dimers hydrolyse GSH IEA Schizosaccharomyces pombe 16856 R-SSC-1655879 https://reactome.org/PathwayBrowser/#/R-SSC-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Sus scrofa 16856 R-SSC-176059 https://reactome.org/PathwayBrowser/#/R-SSC-176059 GST trimers transfer GS from GSH to luminal substrates IEA Sus scrofa 16856 R-SSC-2161660 https://reactome.org/PathwayBrowser/#/R-SSC-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Sus scrofa 16856 R-SSC-3301943 https://reactome.org/PathwayBrowser/#/R-SSC-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Sus scrofa 16856 R-SSC-3323013 https://reactome.org/PathwayBrowser/#/R-SSC-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 16856 R-SSC-3323079 https://reactome.org/PathwayBrowser/#/R-SSC-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 16856 R-SSC-3341397 https://reactome.org/PathwayBrowser/#/R-SSC-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 16856 R-SSC-5693724 https://reactome.org/PathwayBrowser/#/R-SSC-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Sus scrofa 16856 R-SSC-6799695 https://reactome.org/PathwayBrowser/#/R-SSC-6799695 GPX5,6 reduce H2O2 to H2O IEA Sus scrofa 16856 R-SSC-8943279 https://reactome.org/PathwayBrowser/#/R-SSC-8943279 GGT dimers hydrolyse GSH IEA Sus scrofa 16856 R-SSC-9011595 https://reactome.org/PathwayBrowser/#/R-SSC-9011595 GSTZ1 dimer dehalogenates DCA IEA Sus scrofa 16856 R-XTR-1655879 https://reactome.org/PathwayBrowser/#/R-XTR-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Xenopus tropicalis 16856 R-XTR-176059 https://reactome.org/PathwayBrowser/#/R-XTR-176059 GST trimers transfer GS from GSH to luminal substrates IEA Xenopus tropicalis 16856 R-XTR-2161660 https://reactome.org/PathwayBrowser/#/R-XTR-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Xenopus tropicalis 16856 R-XTR-3323079 https://reactome.org/PathwayBrowser/#/R-XTR-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 16856 R-XTR-5693724 https://reactome.org/PathwayBrowser/#/R-XTR-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Xenopus tropicalis 16856 R-XTR-9011595 https://reactome.org/PathwayBrowser/#/R-XTR-9011595 GSTZ1 dimer dehalogenates DCA IEA Xenopus tropicalis 168585 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 168585 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 168585 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 168585 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 168585 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 168585 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 168585 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 168585 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 168585 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 16862 R-HSA-113442 https://reactome.org/PathwayBrowser/#/R-HSA-113442 RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites IEA Homo sapiens 16862 R-SCE-111946 https://reactome.org/PathwayBrowser/#/R-SCE-111946 RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites TAS Saccharomyces cerevisiae 16870 R-BTA-1482612 https://reactome.org/PathwayBrowser/#/R-BTA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 16870 R-BTA-1482685 https://reactome.org/PathwayBrowser/#/R-BTA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 16870 R-BTA-6814254 https://reactome.org/PathwayBrowser/#/R-BTA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Bos taurus 16870 R-BTA-8952251 https://reactome.org/PathwayBrowser/#/R-BTA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Bos taurus 16870 R-CEL-6814254 https://reactome.org/PathwayBrowser/#/R-CEL-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Caenorhabditis elegans 16870 R-CEL-8952251 https://reactome.org/PathwayBrowser/#/R-CEL-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Caenorhabditis elegans 16870 R-CFA-1482612 https://reactome.org/PathwayBrowser/#/R-CFA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 16870 R-CFA-1482685 https://reactome.org/PathwayBrowser/#/R-CFA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 16870 R-CFA-6814254 https://reactome.org/PathwayBrowser/#/R-CFA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Canis familiaris 16870 R-CFA-8952251 https://reactome.org/PathwayBrowser/#/R-CFA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Canis familiaris 16870 R-DDI-1482612 https://reactome.org/PathwayBrowser/#/R-DDI-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Dictyostelium discoideum 16870 R-DDI-1482685 https://reactome.org/PathwayBrowser/#/R-DDI-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Dictyostelium discoideum 16870 R-DME-6814254 https://reactome.org/PathwayBrowser/#/R-DME-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Drosophila melanogaster 16870 R-DME-8952251 https://reactome.org/PathwayBrowser/#/R-DME-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Drosophila melanogaster 16870 R-DRE-1482612 https://reactome.org/PathwayBrowser/#/R-DRE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 16870 R-DRE-1482629 https://reactome.org/PathwayBrowser/#/R-DRE-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Danio rerio 16870 R-DRE-1482685 https://reactome.org/PathwayBrowser/#/R-DRE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 16870 R-DRE-1482696 https://reactome.org/PathwayBrowser/#/R-DRE-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Danio rerio 16870 R-GGA-1482612 https://reactome.org/PathwayBrowser/#/R-GGA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 16870 R-GGA-1482685 https://reactome.org/PathwayBrowser/#/R-GGA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 16870 R-GGA-6814254 https://reactome.org/PathwayBrowser/#/R-GGA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Gallus gallus 16870 R-GGA-8952251 https://reactome.org/PathwayBrowser/#/R-GGA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Gallus gallus 16870 R-HSA-1482612 https://reactome.org/PathwayBrowser/#/R-HSA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 16870 R-HSA-1482629 https://reactome.org/PathwayBrowser/#/R-HSA-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C TAS Homo sapiens 16870 R-HSA-1482685 https://reactome.org/PathwayBrowser/#/R-HSA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 16870 R-HSA-1482696 https://reactome.org/PathwayBrowser/#/R-HSA-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C TAS Homo sapiens 16870 R-HSA-1483116 https://reactome.org/PathwayBrowser/#/R-HSA-1483116 GPCho is hydrolyzed to Cho and G3P by GPCPD1 IEA Homo sapiens 16870 R-HSA-6814132 https://reactome.org/PathwayBrowser/#/R-HSA-6814132 GDPD5 hydrolyzes GPCho IEA Homo sapiens 16870 R-HSA-6814254 https://reactome.org/PathwayBrowser/#/R-HSA-6814254 PNPLA6 hydrolyzes LysoPtdCho TAS Homo sapiens 16870 R-HSA-6814766 https://reactome.org/PathwayBrowser/#/R-HSA-6814766 GDPD1 hydrolyzes LysoPtdCho IEA Homo sapiens 16870 R-HSA-6814778 https://reactome.org/PathwayBrowser/#/R-HSA-6814778 GDPD3 hydrolyzes LysoPtdCho IEA Homo sapiens 16870 R-HSA-8847912 https://reactome.org/PathwayBrowser/#/R-HSA-8847912 PNPLA7 hydrolyzes LysoPtdCho IEA Homo sapiens 16870 R-HSA-8952251 https://reactome.org/PathwayBrowser/#/R-HSA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) TAS Homo sapiens 16870 R-MMU-1482612 https://reactome.org/PathwayBrowser/#/R-MMU-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 16870 R-MMU-1482629 https://reactome.org/PathwayBrowser/#/R-MMU-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Mus musculus 16870 R-MMU-1482685 https://reactome.org/PathwayBrowser/#/R-MMU-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 16870 R-MMU-1482696 https://reactome.org/PathwayBrowser/#/R-MMU-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Mus musculus 16870 R-MMU-1483112 https://reactome.org/PathwayBrowser/#/R-MMU-1483112 GPCho is hydrolyzed to Cho and G3P by Gpcpd1 TAS Mus musculus 16870 R-MMU-6814137 https://reactome.org/PathwayBrowser/#/R-MMU-6814137 Gdpd5 hydrolyzes GPCho TAS Mus musculus 16870 R-MMU-6814254 https://reactome.org/PathwayBrowser/#/R-MMU-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Mus musculus 16870 R-MMU-8847424 https://reactome.org/PathwayBrowser/#/R-MMU-8847424 Gdpd1 hydrolyzes LysoPtdCho TAS Mus musculus 16870 R-MMU-8847427 https://reactome.org/PathwayBrowser/#/R-MMU-8847427 Gdpd3 hydrolyzes LysoPtdCho TAS Mus musculus 16870 R-MMU-8847904 https://reactome.org/PathwayBrowser/#/R-MMU-8847904 Pnpla7 hydrolyzes LysoPtdCho TAS Mus musculus 16870 R-MMU-8952251 https://reactome.org/PathwayBrowser/#/R-MMU-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Mus musculus 16870 R-RNO-1482612 https://reactome.org/PathwayBrowser/#/R-RNO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 16870 R-RNO-1482629 https://reactome.org/PathwayBrowser/#/R-RNO-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Rattus norvegicus 16870 R-RNO-1482685 https://reactome.org/PathwayBrowser/#/R-RNO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 16870 R-RNO-1482696 https://reactome.org/PathwayBrowser/#/R-RNO-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Rattus norvegicus 16870 R-RNO-6814254 https://reactome.org/PathwayBrowser/#/R-RNO-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Rattus norvegicus 16870 R-RNO-8952251 https://reactome.org/PathwayBrowser/#/R-RNO-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Rattus norvegicus 16870 R-SCE-1482612 https://reactome.org/PathwayBrowser/#/R-SCE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 16870 R-SCE-1482629 https://reactome.org/PathwayBrowser/#/R-SCE-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Saccharomyces cerevisiae 16870 R-SCE-1482685 https://reactome.org/PathwayBrowser/#/R-SCE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 16870 R-SCE-1482696 https://reactome.org/PathwayBrowser/#/R-SCE-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Saccharomyces cerevisiae 16870 R-SCE-6814254 https://reactome.org/PathwayBrowser/#/R-SCE-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Saccharomyces cerevisiae 16870 R-SCE-8952251 https://reactome.org/PathwayBrowser/#/R-SCE-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Saccharomyces cerevisiae 16870 R-SPO-1482612 https://reactome.org/PathwayBrowser/#/R-SPO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 16870 R-SPO-1482629 https://reactome.org/PathwayBrowser/#/R-SPO-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Schizosaccharomyces pombe 16870 R-SPO-1482685 https://reactome.org/PathwayBrowser/#/R-SPO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 16870 R-SPO-1482696 https://reactome.org/PathwayBrowser/#/R-SPO-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Schizosaccharomyces pombe 16870 R-SPO-6814254 https://reactome.org/PathwayBrowser/#/R-SPO-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Schizosaccharomyces pombe 16870 R-SSC-1482612 https://reactome.org/PathwayBrowser/#/R-SSC-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 16870 R-SSC-1482685 https://reactome.org/PathwayBrowser/#/R-SSC-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 16870 R-SSC-6814254 https://reactome.org/PathwayBrowser/#/R-SSC-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Sus scrofa 16870 R-SSC-8952251 https://reactome.org/PathwayBrowser/#/R-SSC-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Sus scrofa 16870 R-XTR-1482612 https://reactome.org/PathwayBrowser/#/R-XTR-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 16870 R-XTR-1482685 https://reactome.org/PathwayBrowser/#/R-XTR-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 16870 R-XTR-8952251 https://reactome.org/PathwayBrowser/#/R-XTR-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Xenopus tropicalis 168721 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 168721 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 168721 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 168721 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 168721 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 168721 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 168721 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 168721 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 168721 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 16875 R-BTA-5662660 https://reactome.org/PathwayBrowser/#/R-BTA-5662660 Dopachrome is transformed to DHICA by DCT IEA Bos taurus 16875 R-BTA-5663050 https://reactome.org/PathwayBrowser/#/R-BTA-5663050 DHI and DHICA polymerize forming eumelanin IEA Bos taurus 16875 R-BTA-8878581 https://reactome.org/PathwayBrowser/#/R-BTA-8878581 TYRP1 oxidises DHICA to IQCA IEA Bos taurus 16875 R-CEL-5662660 https://reactome.org/PathwayBrowser/#/R-CEL-5662660 Dopachrome is transformed to DHICA by DCT IEA Caenorhabditis elegans 16875 R-CEL-5663050 https://reactome.org/PathwayBrowser/#/R-CEL-5663050 DHI and DHICA polymerize forming eumelanin IEA Caenorhabditis elegans 16875 R-CEL-8878581 https://reactome.org/PathwayBrowser/#/R-CEL-8878581 TYRP1 oxidises DHICA to IQCA IEA Caenorhabditis elegans 16875 R-CFA-5662660 https://reactome.org/PathwayBrowser/#/R-CFA-5662660 Dopachrome is transformed to DHICA by DCT IEA Canis familiaris 16875 R-CFA-5663050 https://reactome.org/PathwayBrowser/#/R-CFA-5663050 DHI and DHICA polymerize forming eumelanin IEA Canis familiaris 16875 R-CFA-8878581 https://reactome.org/PathwayBrowser/#/R-CFA-8878581 TYRP1 oxidises DHICA to IQCA IEA Canis familiaris 16875 R-DDI-5662660 https://reactome.org/PathwayBrowser/#/R-DDI-5662660 Dopachrome is transformed to DHICA by DCT IEA Dictyostelium discoideum 16875 R-DDI-5663050 https://reactome.org/PathwayBrowser/#/R-DDI-5663050 DHI and DHICA polymerize forming eumelanin IEA Dictyostelium discoideum 16875 R-DDI-8878581 https://reactome.org/PathwayBrowser/#/R-DDI-8878581 TYRP1 oxidises DHICA to IQCA IEA Dictyostelium discoideum 16875 R-DRE-5662660 https://reactome.org/PathwayBrowser/#/R-DRE-5662660 Dopachrome is transformed to DHICA by DCT IEA Danio rerio 16875 R-DRE-8878581 https://reactome.org/PathwayBrowser/#/R-DRE-8878581 TYRP1 oxidises DHICA to IQCA IEA Danio rerio 16875 R-GGA-5662660 https://reactome.org/PathwayBrowser/#/R-GGA-5662660 Dopachrome is transformed to DHICA by DCT IEA Gallus gallus 16875 R-GGA-5663050 https://reactome.org/PathwayBrowser/#/R-GGA-5663050 DHI and DHICA polymerize forming eumelanin IEA Gallus gallus 16875 R-GGA-8878581 https://reactome.org/PathwayBrowser/#/R-GGA-8878581 TYRP1 oxidises DHICA to IQCA IEA Gallus gallus 16875 R-HSA-5662660 https://reactome.org/PathwayBrowser/#/R-HSA-5662660 Dopachrome is transformed to DHICA by DCT TAS Homo sapiens 16875 R-HSA-5663050 https://reactome.org/PathwayBrowser/#/R-HSA-5663050 DHI and DHICA polymerize forming eumelanin TAS Homo sapiens 16875 R-HSA-8878581 https://reactome.org/PathwayBrowser/#/R-HSA-8878581 TYRP1 oxidises DHICA to IQCA TAS Homo sapiens 16875 R-MMU-5662660 https://reactome.org/PathwayBrowser/#/R-MMU-5662660 Dopachrome is transformed to DHICA by DCT IEA Mus musculus 16875 R-MMU-5663050 https://reactome.org/PathwayBrowser/#/R-MMU-5663050 DHI and DHICA polymerize forming eumelanin IEA Mus musculus 16875 R-MMU-8878581 https://reactome.org/PathwayBrowser/#/R-MMU-8878581 TYRP1 oxidises DHICA to IQCA IEA Mus musculus 16875 R-RNO-5662660 https://reactome.org/PathwayBrowser/#/R-RNO-5662660 Dopachrome is transformed to DHICA by DCT IEA Rattus norvegicus 16875 R-RNO-5663050 https://reactome.org/PathwayBrowser/#/R-RNO-5663050 DHI and DHICA polymerize forming eumelanin IEA Rattus norvegicus 16875 R-RNO-8878581 https://reactome.org/PathwayBrowser/#/R-RNO-8878581 TYRP1 oxidises DHICA to IQCA IEA Rattus norvegicus 16875 R-SSC-5662660 https://reactome.org/PathwayBrowser/#/R-SSC-5662660 Dopachrome is transformed to DHICA by DCT IEA Sus scrofa 16875 R-SSC-5663050 https://reactome.org/PathwayBrowser/#/R-SSC-5663050 DHI and DHICA polymerize forming eumelanin IEA Sus scrofa 16875 R-SSC-8878581 https://reactome.org/PathwayBrowser/#/R-SSC-8878581 TYRP1 oxidises DHICA to IQCA IEA Sus scrofa 16875 R-XTR-5662660 https://reactome.org/PathwayBrowser/#/R-XTR-5662660 Dopachrome is transformed to DHICA by DCT IEA Xenopus tropicalis 16875 R-XTR-5663050 https://reactome.org/PathwayBrowser/#/R-XTR-5663050 DHI and DHICA polymerize forming eumelanin IEA Xenopus tropicalis 16875 R-XTR-8878581 https://reactome.org/PathwayBrowser/#/R-XTR-8878581 TYRP1 oxidises DHICA to IQCA IEA Xenopus tropicalis 16881 R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 16881 R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 16881 R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 16881 R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 16881 R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 16881 R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 16881 R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 16881 R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 16881 R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 16881 R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 16881 R-SSC-211968 https://reactome.org/PathwayBrowser/#/R-SSC-211968 CYP2W1 oxidises INDOL IEA Sus scrofa 16881 R-XTR-211968 https://reactome.org/PathwayBrowser/#/R-XTR-211968 CYP2W1 oxidises INDOL IEA Xenopus tropicalis 16891 R-BTA-389684 https://reactome.org/PathwayBrowser/#/R-BTA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Bos taurus 16891 R-BTA-389821 https://reactome.org/PathwayBrowser/#/R-BTA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Bos taurus 16891 R-BTA-389826 https://reactome.org/PathwayBrowser/#/R-BTA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Bos taurus 16891 R-BTA-389842 https://reactome.org/PathwayBrowser/#/R-BTA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Bos taurus 16891 R-BTA-389862 https://reactome.org/PathwayBrowser/#/R-BTA-389862 Conversion of glyoxylate to oxalate IEA Bos taurus 16891 R-CEL-389684 https://reactome.org/PathwayBrowser/#/R-CEL-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Caenorhabditis elegans 16891 R-CEL-389821 https://reactome.org/PathwayBrowser/#/R-CEL-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Caenorhabditis elegans 16891 R-CEL-389842 https://reactome.org/PathwayBrowser/#/R-CEL-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Caenorhabditis elegans 16891 R-CEL-389862 https://reactome.org/PathwayBrowser/#/R-CEL-389862 Conversion of glyoxylate to oxalate IEA Caenorhabditis elegans 16891 R-CFA-389684 https://reactome.org/PathwayBrowser/#/R-CFA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Canis familiaris 16891 R-CFA-389821 https://reactome.org/PathwayBrowser/#/R-CFA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Canis familiaris 16891 R-CFA-389826 https://reactome.org/PathwayBrowser/#/R-CFA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Canis familiaris 16891 R-CFA-389842 https://reactome.org/PathwayBrowser/#/R-CFA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Canis familiaris 16891 R-CFA-389862 https://reactome.org/PathwayBrowser/#/R-CFA-389862 Conversion of glyoxylate to oxalate IEA Canis familiaris 16891 R-DDI-389684 https://reactome.org/PathwayBrowser/#/R-DDI-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Dictyostelium discoideum 16891 R-DDI-389821 https://reactome.org/PathwayBrowser/#/R-DDI-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Dictyostelium discoideum 16891 R-DDI-389842 https://reactome.org/PathwayBrowser/#/R-DDI-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Dictyostelium discoideum 16891 R-DDI-389862 https://reactome.org/PathwayBrowser/#/R-DDI-389862 Conversion of glyoxylate to oxalate IEA Dictyostelium discoideum 16891 R-DME-389684 https://reactome.org/PathwayBrowser/#/R-DME-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Drosophila melanogaster 16891 R-DME-389821 https://reactome.org/PathwayBrowser/#/R-DME-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Drosophila melanogaster 16891 R-DME-389826 https://reactome.org/PathwayBrowser/#/R-DME-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Drosophila melanogaster 16891 R-DME-389842 https://reactome.org/PathwayBrowser/#/R-DME-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Drosophila melanogaster 16891 R-DME-389862 https://reactome.org/PathwayBrowser/#/R-DME-389862 Conversion of glyoxylate to oxalate IEA Drosophila melanogaster 16891 R-DRE-389684 https://reactome.org/PathwayBrowser/#/R-DRE-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Danio rerio 16891 R-DRE-389821 https://reactome.org/PathwayBrowser/#/R-DRE-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Danio rerio 16891 R-DRE-389826 https://reactome.org/PathwayBrowser/#/R-DRE-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Danio rerio 16891 R-DRE-389842 https://reactome.org/PathwayBrowser/#/R-DRE-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Danio rerio 16891 R-DRE-389862 https://reactome.org/PathwayBrowser/#/R-DRE-389862 Conversion of glyoxylate to oxalate IEA Danio rerio 16891 R-GGA-389684 https://reactome.org/PathwayBrowser/#/R-GGA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Gallus gallus 16891 R-GGA-389821 https://reactome.org/PathwayBrowser/#/R-GGA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Gallus gallus 16891 R-GGA-389826 https://reactome.org/PathwayBrowser/#/R-GGA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Gallus gallus 16891 R-GGA-389842 https://reactome.org/PathwayBrowser/#/R-GGA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Gallus gallus 16891 R-GGA-389862 https://reactome.org/PathwayBrowser/#/R-GGA-389862 Conversion of glyoxylate to oxalate IEA Gallus gallus 16891 R-HSA-389684 https://reactome.org/PathwayBrowser/#/R-HSA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] TAS Homo sapiens 16891 R-HSA-389821 https://reactome.org/PathwayBrowser/#/R-HSA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ TAS Homo sapiens 16891 R-HSA-389826 https://reactome.org/PathwayBrowser/#/R-HSA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ TAS Homo sapiens 16891 R-HSA-389842 https://reactome.org/PathwayBrowser/#/R-HSA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate TAS Homo sapiens 16891 R-HSA-389862 https://reactome.org/PathwayBrowser/#/R-HSA-389862 Conversion of glyoxylate to oxalate TAS Homo sapiens 16891 R-HSA-6784434 https://reactome.org/PathwayBrowser/#/R-HSA-6784434 An unknown carrier transports cytosolic glyoxylate to the peroxisome TAS Homo sapiens 16891 R-HSA-6784436 https://reactome.org/PathwayBrowser/#/R-HSA-6784436 An unknown carrier transports mitochondrial glyoxylate to the cytosol TAS Homo sapiens 16891 R-MMU-389684 https://reactome.org/PathwayBrowser/#/R-MMU-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Mus musculus 16891 R-MMU-389821 https://reactome.org/PathwayBrowser/#/R-MMU-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Mus musculus 16891 R-MMU-389826 https://reactome.org/PathwayBrowser/#/R-MMU-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Mus musculus 16891 R-MMU-389842 https://reactome.org/PathwayBrowser/#/R-MMU-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Mus musculus 16891 R-MMU-389862 https://reactome.org/PathwayBrowser/#/R-MMU-389862 Conversion of glyoxylate to oxalate IEA Mus musculus 16891 R-RNO-389684 https://reactome.org/PathwayBrowser/#/R-RNO-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Rattus norvegicus 16891 R-RNO-389821 https://reactome.org/PathwayBrowser/#/R-RNO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Rattus norvegicus 16891 R-RNO-389826 https://reactome.org/PathwayBrowser/#/R-RNO-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Rattus norvegicus 16891 R-RNO-389842 https://reactome.org/PathwayBrowser/#/R-RNO-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Rattus norvegicus 16891 R-RNO-389862 https://reactome.org/PathwayBrowser/#/R-RNO-389862 Conversion of glyoxylate to oxalate IEA Rattus norvegicus 16891 R-SPO-389821 https://reactome.org/PathwayBrowser/#/R-SPO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Schizosaccharomyces pombe 16891 R-SSC-389684 https://reactome.org/PathwayBrowser/#/R-SSC-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Sus scrofa 16891 R-SSC-389821 https://reactome.org/PathwayBrowser/#/R-SSC-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Sus scrofa 16891 R-SSC-389826 https://reactome.org/PathwayBrowser/#/R-SSC-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Sus scrofa 16891 R-SSC-389842 https://reactome.org/PathwayBrowser/#/R-SSC-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Sus scrofa 16891 R-SSC-389862 https://reactome.org/PathwayBrowser/#/R-SSC-389862 Conversion of glyoxylate to oxalate IEA Sus scrofa 16891 R-XTR-389684 https://reactome.org/PathwayBrowser/#/R-XTR-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Xenopus tropicalis 16891 R-XTR-389821 https://reactome.org/PathwayBrowser/#/R-XTR-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Xenopus tropicalis 16891 R-XTR-389826 https://reactome.org/PathwayBrowser/#/R-XTR-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Xenopus tropicalis 16891 R-XTR-389842 https://reactome.org/PathwayBrowser/#/R-XTR-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Xenopus tropicalis 16891 R-XTR-389862 https://reactome.org/PathwayBrowser/#/R-XTR-389862 Conversion of glyoxylate to oxalate IEA Xenopus tropicalis 16897 R-BTA-163751 https://reactome.org/PathwayBrowser/#/R-BTA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Bos taurus 16897 R-BTA-163764 https://reactome.org/PathwayBrowser/#/R-BTA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 16897 R-BTA-71334 https://reactome.org/PathwayBrowser/#/R-BTA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Bos taurus 16897 R-BTA-71335 https://reactome.org/PathwayBrowser/#/R-BTA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Bos taurus 16897 R-CEL-163751 https://reactome.org/PathwayBrowser/#/R-CEL-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Caenorhabditis elegans 16897 R-CEL-163764 https://reactome.org/PathwayBrowser/#/R-CEL-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 16897 R-CEL-71334 https://reactome.org/PathwayBrowser/#/R-CEL-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Caenorhabditis elegans 16897 R-CEL-71335 https://reactome.org/PathwayBrowser/#/R-CEL-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Caenorhabditis elegans 16897 R-CFA-163751 https://reactome.org/PathwayBrowser/#/R-CFA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Canis familiaris 16897 R-CFA-163764 https://reactome.org/PathwayBrowser/#/R-CFA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 16897 R-CFA-71334 https://reactome.org/PathwayBrowser/#/R-CFA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Canis familiaris 16897 R-CFA-71335 https://reactome.org/PathwayBrowser/#/R-CFA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Canis familiaris 16897 R-DDI-163764 https://reactome.org/PathwayBrowser/#/R-DDI-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 16897 R-DDI-71334 https://reactome.org/PathwayBrowser/#/R-DDI-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Dictyostelium discoideum 16897 R-DME-163751 https://reactome.org/PathwayBrowser/#/R-DME-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Drosophila melanogaster 16897 R-DME-163764 https://reactome.org/PathwayBrowser/#/R-DME-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 16897 R-DME-71334 https://reactome.org/PathwayBrowser/#/R-DME-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Drosophila melanogaster 16897 R-DME-71335 https://reactome.org/PathwayBrowser/#/R-DME-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Drosophila melanogaster 16897 R-DRE-163764 https://reactome.org/PathwayBrowser/#/R-DRE-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Danio rerio 16897 R-DRE-71334 https://reactome.org/PathwayBrowser/#/R-DRE-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Danio rerio 16897 R-GGA-163751 https://reactome.org/PathwayBrowser/#/R-GGA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Gallus gallus 16897 R-GGA-163764 https://reactome.org/PathwayBrowser/#/R-GGA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 16897 R-GGA-71334 https://reactome.org/PathwayBrowser/#/R-GGA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Gallus gallus 16897 R-GGA-71335 https://reactome.org/PathwayBrowser/#/R-GGA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Gallus gallus 16897 R-HSA-163751 https://reactome.org/PathwayBrowser/#/R-HSA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate TAS Homo sapiens 16897 R-HSA-163764 https://reactome.org/PathwayBrowser/#/R-HSA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 16897 R-HSA-5659998 https://reactome.org/PathwayBrowser/#/R-HSA-5659998 Defective TALDO1 does not transform Fru(6)P, E4P to SH7P, GA3P TAS Homo sapiens 16897 R-HSA-71334 https://reactome.org/PathwayBrowser/#/R-HSA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate TAS Homo sapiens 16897 R-HSA-71335 https://reactome.org/PathwayBrowser/#/R-HSA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate TAS Homo sapiens 16897 R-MMU-163751 https://reactome.org/PathwayBrowser/#/R-MMU-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Mus musculus 16897 R-MMU-163764 https://reactome.org/PathwayBrowser/#/R-MMU-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 16897 R-MMU-71334 https://reactome.org/PathwayBrowser/#/R-MMU-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Mus musculus 16897 R-MMU-71335 https://reactome.org/PathwayBrowser/#/R-MMU-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Mus musculus 16897 R-MTU-964912 https://reactome.org/PathwayBrowser/#/R-MTU-964912 DHAP from Ery4P and PEP TAS Mycobacterium tuberculosis 16897 R-RNO-163751 https://reactome.org/PathwayBrowser/#/R-RNO-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Rattus norvegicus 16897 R-RNO-163764 https://reactome.org/PathwayBrowser/#/R-RNO-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 16897 R-RNO-71334 https://reactome.org/PathwayBrowser/#/R-RNO-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Rattus norvegicus 16897 R-RNO-71335 https://reactome.org/PathwayBrowser/#/R-RNO-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Rattus norvegicus 16897 R-SCE-163764 https://reactome.org/PathwayBrowser/#/R-SCE-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Saccharomyces cerevisiae 16897 R-SCE-71334 https://reactome.org/PathwayBrowser/#/R-SCE-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Saccharomyces cerevisiae 16897 R-SPO-163764 https://reactome.org/PathwayBrowser/#/R-SPO-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Schizosaccharomyces pombe 16897 R-SPO-71334 https://reactome.org/PathwayBrowser/#/R-SPO-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Schizosaccharomyces pombe 16897 R-SSC-163751 https://reactome.org/PathwayBrowser/#/R-SSC-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Sus scrofa 16897 R-SSC-163764 https://reactome.org/PathwayBrowser/#/R-SSC-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 16897 R-SSC-71334 https://reactome.org/PathwayBrowser/#/R-SSC-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Sus scrofa 16897 R-SSC-71335 https://reactome.org/PathwayBrowser/#/R-SSC-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Sus scrofa 16897 R-XTR-163751 https://reactome.org/PathwayBrowser/#/R-XTR-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Xenopus tropicalis 16897 R-XTR-163764 https://reactome.org/PathwayBrowser/#/R-XTR-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 16897 R-XTR-71334 https://reactome.org/PathwayBrowser/#/R-XTR-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Xenopus tropicalis 16897 R-XTR-71335 https://reactome.org/PathwayBrowser/#/R-XTR-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Xenopus tropicalis 16927 R-BTA-70938 https://reactome.org/PathwayBrowser/#/R-BTA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Bos taurus 16927 R-BTA-70940 https://reactome.org/PathwayBrowser/#/R-BTA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Bos taurus 16927 R-CEL-70938 https://reactome.org/PathwayBrowser/#/R-CEL-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Caenorhabditis elegans 16927 R-CEL-70940 https://reactome.org/PathwayBrowser/#/R-CEL-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Caenorhabditis elegans 16927 R-CFA-70938 https://reactome.org/PathwayBrowser/#/R-CFA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Canis familiaris 16927 R-CFA-70940 https://reactome.org/PathwayBrowser/#/R-CFA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Canis familiaris 16927 R-DDI-70938 https://reactome.org/PathwayBrowser/#/R-DDI-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Dictyostelium discoideum 16927 R-DDI-70940 https://reactome.org/PathwayBrowser/#/R-DDI-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Dictyostelium discoideum 16927 R-DME-70938 https://reactome.org/PathwayBrowser/#/R-DME-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Drosophila melanogaster 16927 R-DME-70940 https://reactome.org/PathwayBrowser/#/R-DME-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Drosophila melanogaster 16927 R-DRE-70938 https://reactome.org/PathwayBrowser/#/R-DRE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Danio rerio 16927 R-DRE-70940 https://reactome.org/PathwayBrowser/#/R-DRE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Danio rerio 16927 R-GGA-70938 https://reactome.org/PathwayBrowser/#/R-GGA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Gallus gallus 16927 R-GGA-70940 https://reactome.org/PathwayBrowser/#/R-GGA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Gallus gallus 16927 R-HSA-70938 https://reactome.org/PathwayBrowser/#/R-HSA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O TAS Homo sapiens 16927 R-HSA-70940 https://reactome.org/PathwayBrowser/#/R-HSA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ TAS Homo sapiens 16927 R-MMU-70938 https://reactome.org/PathwayBrowser/#/R-MMU-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Mus musculus 16927 R-MMU-70940 https://reactome.org/PathwayBrowser/#/R-MMU-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Mus musculus 16927 R-RNO-70938 https://reactome.org/PathwayBrowser/#/R-RNO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Rattus norvegicus 16927 R-RNO-70940 https://reactome.org/PathwayBrowser/#/R-RNO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Rattus norvegicus 16927 R-SCE-70938 https://reactome.org/PathwayBrowser/#/R-SCE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Saccharomyces cerevisiae 16927 R-SCE-70940 https://reactome.org/PathwayBrowser/#/R-SCE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Saccharomyces cerevisiae 16927 R-SPO-70938 https://reactome.org/PathwayBrowser/#/R-SPO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Schizosaccharomyces pombe 16927 R-SPO-70940 https://reactome.org/PathwayBrowser/#/R-SPO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Schizosaccharomyces pombe 16927 R-SSC-70938 https://reactome.org/PathwayBrowser/#/R-SSC-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Sus scrofa 16927 R-SSC-70940 https://reactome.org/PathwayBrowser/#/R-SSC-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Sus scrofa 16927 R-XTR-70938 https://reactome.org/PathwayBrowser/#/R-XTR-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Xenopus tropicalis 16927 R-XTR-70940 https://reactome.org/PathwayBrowser/#/R-XTR-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Xenopus tropicalis 16929 R-DRE-1482545 https://reactome.org/PathwayBrowser/#/R-DRE-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Danio rerio 16929 R-DRE-1482571 https://reactome.org/PathwayBrowser/#/R-DRE-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Danio rerio 16929 R-HSA-1482545 https://reactome.org/PathwayBrowser/#/R-HSA-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C TAS Homo sapiens 16929 R-HSA-1482571 https://reactome.org/PathwayBrowser/#/R-HSA-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C TAS Homo sapiens 16929 R-HSA-1483107 https://reactome.org/PathwayBrowser/#/R-HSA-1483107 GPETA is hydrolyzed to ETA and G3P by GPCPD1 IEA Homo sapiens 16929 R-MMU-1482545 https://reactome.org/PathwayBrowser/#/R-MMU-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Mus musculus 16929 R-MMU-1482571 https://reactome.org/PathwayBrowser/#/R-MMU-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Mus musculus 16929 R-MMU-1483231 https://reactome.org/PathwayBrowser/#/R-MMU-1483231 GPETA is hydrolyzed to ETA and G3P by Gpcpd1 TAS Mus musculus 16929 R-RNO-1482545 https://reactome.org/PathwayBrowser/#/R-RNO-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Rattus norvegicus 16929 R-RNO-1482571 https://reactome.org/PathwayBrowser/#/R-RNO-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Rattus norvegicus 16929 R-SCE-1482545 https://reactome.org/PathwayBrowser/#/R-SCE-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Saccharomyces cerevisiae 16929 R-SCE-1482571 https://reactome.org/PathwayBrowser/#/R-SCE-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Saccharomyces cerevisiae 16929 R-SPO-1482545 https://reactome.org/PathwayBrowser/#/R-SPO-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Schizosaccharomyces pombe 16929 R-SPO-1482571 https://reactome.org/PathwayBrowser/#/R-SPO-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Schizosaccharomyces pombe 16938 R-BTA-70377 https://reactome.org/PathwayBrowser/#/R-BTA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Bos taurus 16938 R-BTA-71296 https://reactome.org/PathwayBrowser/#/R-BTA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Bos taurus 16938 R-CEL-70377 https://reactome.org/PathwayBrowser/#/R-CEL-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Caenorhabditis elegans 16938 R-CEL-71296 https://reactome.org/PathwayBrowser/#/R-CEL-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Caenorhabditis elegans 16938 R-CFA-70377 https://reactome.org/PathwayBrowser/#/R-CFA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Canis familiaris 16938 R-CFA-71296 https://reactome.org/PathwayBrowser/#/R-CFA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Canis familiaris 16938 R-DDI-70377 https://reactome.org/PathwayBrowser/#/R-DDI-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Dictyostelium discoideum 16938 R-DDI-71296 https://reactome.org/PathwayBrowser/#/R-DDI-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Dictyostelium discoideum 16938 R-DME-70377 https://reactome.org/PathwayBrowser/#/R-DME-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Drosophila melanogaster 16938 R-DME-71296 https://reactome.org/PathwayBrowser/#/R-DME-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Drosophila melanogaster 16938 R-GGA-71296 https://reactome.org/PathwayBrowser/#/R-GGA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Gallus gallus 16938 R-HSA-1500781 https://reactome.org/PathwayBrowser/#/R-HSA-1500781 Fgd1 reactivates F420 TAS Homo sapiens 16938 R-HSA-70377 https://reactome.org/PathwayBrowser/#/R-HSA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ TAS Homo sapiens 16938 R-HSA-71296 https://reactome.org/PathwayBrowser/#/R-HSA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate TAS Homo sapiens 16938 R-MMU-70377 https://reactome.org/PathwayBrowser/#/R-MMU-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Mus musculus 16938 R-MMU-71296 https://reactome.org/PathwayBrowser/#/R-MMU-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Mus musculus 16938 R-PFA-70377 https://reactome.org/PathwayBrowser/#/R-PFA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Plasmodium falciparum 16938 R-RNO-70377 https://reactome.org/PathwayBrowser/#/R-RNO-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Rattus norvegicus 16938 R-RNO-71296 https://reactome.org/PathwayBrowser/#/R-RNO-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Rattus norvegicus 16938 R-SCE-70377 https://reactome.org/PathwayBrowser/#/R-SCE-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Saccharomyces cerevisiae 16938 R-SCE-71296 https://reactome.org/PathwayBrowser/#/R-SCE-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Saccharomyces cerevisiae 16938 R-SPO-70377 https://reactome.org/PathwayBrowser/#/R-SPO-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Schizosaccharomyces pombe 16938 R-SPO-71296 https://reactome.org/PathwayBrowser/#/R-SPO-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Schizosaccharomyces pombe 16938 R-SSC-70377 https://reactome.org/PathwayBrowser/#/R-SSC-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Sus scrofa 16938 R-SSC-71296 https://reactome.org/PathwayBrowser/#/R-SSC-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Sus scrofa 16938 R-XTR-70377 https://reactome.org/PathwayBrowser/#/R-XTR-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Xenopus tropicalis 16938 R-XTR-71296 https://reactome.org/PathwayBrowser/#/R-XTR-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Xenopus tropicalis 16946 R-BTA-71200 https://reactome.org/PathwayBrowser/#/R-BTA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Bos taurus 16946 R-BTA-893583 https://reactome.org/PathwayBrowser/#/R-BTA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Bos taurus 16946 R-BTA-893596 https://reactome.org/PathwayBrowser/#/R-BTA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Bos taurus 16946 R-CEL-71200 https://reactome.org/PathwayBrowser/#/R-CEL-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Caenorhabditis elegans 16946 R-CEL-893596 https://reactome.org/PathwayBrowser/#/R-CEL-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Caenorhabditis elegans 16946 R-CFA-71200 https://reactome.org/PathwayBrowser/#/R-CFA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Canis familiaris 16946 R-CFA-893583 https://reactome.org/PathwayBrowser/#/R-CFA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Canis familiaris 16946 R-CFA-893596 https://reactome.org/PathwayBrowser/#/R-CFA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Canis familiaris 16946 R-DDI-71200 https://reactome.org/PathwayBrowser/#/R-DDI-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Dictyostelium discoideum 16946 R-DDI-893583 https://reactome.org/PathwayBrowser/#/R-DDI-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Dictyostelium discoideum 16946 R-DDI-893596 https://reactome.org/PathwayBrowser/#/R-DDI-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Dictyostelium discoideum 16946 R-DME-71200 https://reactome.org/PathwayBrowser/#/R-DME-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Drosophila melanogaster 16946 R-DME-893596 https://reactome.org/PathwayBrowser/#/R-DME-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Drosophila melanogaster 16946 R-DRE-71200 https://reactome.org/PathwayBrowser/#/R-DRE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Danio rerio 16946 R-DRE-893596 https://reactome.org/PathwayBrowser/#/R-DRE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Danio rerio 16946 R-GGA-71200 https://reactome.org/PathwayBrowser/#/R-GGA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Gallus gallus 16946 R-GGA-893583 https://reactome.org/PathwayBrowser/#/R-GGA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Gallus gallus 16946 R-GGA-893596 https://reactome.org/PathwayBrowser/#/R-GGA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Gallus gallus 16946 R-HSA-71189 https://reactome.org/PathwayBrowser/#/R-HSA-71189 AFMID hydrolyses NFK to L-KYN IEA Homo sapiens 16946 R-HSA-71200 https://reactome.org/PathwayBrowser/#/R-HSA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O TAS Homo sapiens 16946 R-HSA-893583 https://reactome.org/PathwayBrowser/#/R-HSA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate TAS Homo sapiens 16946 R-HSA-893596 https://reactome.org/PathwayBrowser/#/R-HSA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu TAS Homo sapiens 16946 R-HSA-901097 https://reactome.org/PathwayBrowser/#/R-HSA-901097 kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2] IEA Homo sapiens 16946 R-MMU-71196 https://reactome.org/PathwayBrowser/#/R-MMU-71196 N-formylkynurenine + H2O => kynurenine + formate [mouse] TAS Mus musculus 16946 R-MMU-71200 https://reactome.org/PathwayBrowser/#/R-MMU-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Mus musculus 16946 R-MMU-893583 https://reactome.org/PathwayBrowser/#/R-MMU-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Mus musculus 16946 R-MMU-893596 https://reactome.org/PathwayBrowser/#/R-MMU-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Mus musculus 16946 R-RNO-71200 https://reactome.org/PathwayBrowser/#/R-RNO-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Rattus norvegicus 16946 R-RNO-893583 https://reactome.org/PathwayBrowser/#/R-RNO-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Rattus norvegicus 16946 R-RNO-893596 https://reactome.org/PathwayBrowser/#/R-RNO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Rattus norvegicus 16946 R-SCE-71200 https://reactome.org/PathwayBrowser/#/R-SCE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Saccharomyces cerevisiae 16946 R-SCE-893583 https://reactome.org/PathwayBrowser/#/R-SCE-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Saccharomyces cerevisiae 16946 R-SCE-893596 https://reactome.org/PathwayBrowser/#/R-SCE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Saccharomyces cerevisiae 16946 R-SPO-893583 https://reactome.org/PathwayBrowser/#/R-SPO-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Schizosaccharomyces pombe 16946 R-SPO-893596 https://reactome.org/PathwayBrowser/#/R-SPO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Schizosaccharomyces pombe 16946 R-SSC-71200 https://reactome.org/PathwayBrowser/#/R-SSC-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Sus scrofa 16946 R-SSC-893583 https://reactome.org/PathwayBrowser/#/R-SSC-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Sus scrofa 16946 R-SSC-893596 https://reactome.org/PathwayBrowser/#/R-SSC-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Sus scrofa 16946 R-XTR-71200 https://reactome.org/PathwayBrowser/#/R-XTR-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Xenopus tropicalis 16946 R-XTR-893583 https://reactome.org/PathwayBrowser/#/R-XTR-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Xenopus tropicalis 16946 R-XTR-893596 https://reactome.org/PathwayBrowser/#/R-XTR-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Xenopus tropicalis 16947 R-BTA-70971 https://reactome.org/PathwayBrowser/#/R-BTA-70971 ACO2 isomerizes citrate IEA Bos taurus 16947 R-BTA-70975 https://reactome.org/PathwayBrowser/#/R-BTA-70975 CS acetylates OA to citrate IEA Bos taurus 16947 R-BTA-75849 https://reactome.org/PathwayBrowser/#/R-BTA-75849 SLC25A1 exchanges CIT and MAL IEA Bos taurus 16947 R-CEL-70971 https://reactome.org/PathwayBrowser/#/R-CEL-70971 ACO2 isomerizes citrate IEA Caenorhabditis elegans 16947 R-CEL-70975 https://reactome.org/PathwayBrowser/#/R-CEL-70975 CS acetylates OA to citrate IEA Caenorhabditis elegans 16947 R-CEL-75849 https://reactome.org/PathwayBrowser/#/R-CEL-75849 SLC25A1 exchanges CIT and MAL IEA Caenorhabditis elegans 16947 R-CFA-70971 https://reactome.org/PathwayBrowser/#/R-CFA-70971 ACO2 isomerizes citrate IEA Canis familiaris 16947 R-CFA-70975 https://reactome.org/PathwayBrowser/#/R-CFA-70975 CS acetylates OA to citrate IEA Canis familiaris 16947 R-CFA-75849 https://reactome.org/PathwayBrowser/#/R-CFA-75849 SLC25A1 exchanges CIT and MAL IEA Canis familiaris 16947 R-DDI-70971 https://reactome.org/PathwayBrowser/#/R-DDI-70971 ACO2 isomerizes citrate IEA Dictyostelium discoideum 16947 R-DDI-70975 https://reactome.org/PathwayBrowser/#/R-DDI-70975 CS acetylates OA to citrate IEA Dictyostelium discoideum 16947 R-DME-70971 https://reactome.org/PathwayBrowser/#/R-DME-70971 ACO2 isomerizes citrate IEA Drosophila melanogaster 16947 R-DME-70975 https://reactome.org/PathwayBrowser/#/R-DME-70975 CS acetylates OA to citrate IEA Drosophila melanogaster 16947 R-DME-75849 https://reactome.org/PathwayBrowser/#/R-DME-75849 SLC25A1 exchanges CIT and MAL IEA Drosophila melanogaster 16947 R-DRE-70971 https://reactome.org/PathwayBrowser/#/R-DRE-70971 ACO2 isomerizes citrate IEA Danio rerio 16947 R-DRE-70975 https://reactome.org/PathwayBrowser/#/R-DRE-70975 CS acetylates OA to citrate IEA Danio rerio 16947 R-DRE-75849 https://reactome.org/PathwayBrowser/#/R-DRE-75849 SLC25A1 exchanges CIT and MAL IEA Danio rerio 16947 R-GGA-372723 https://reactome.org/PathwayBrowser/#/R-GGA-372723 phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] <=> phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix] IEA Gallus gallus 16947 R-GGA-373006 https://reactome.org/PathwayBrowser/#/R-GGA-373006 acetyl-CoA + H2O + oxaloacetate => citrate + CoA TAS Gallus gallus 16947 R-GGA-373015 https://reactome.org/PathwayBrowser/#/R-GGA-373015 citrate <=> isocitrate TAS Gallus gallus 16947 R-GGA-373140 https://reactome.org/PathwayBrowser/#/R-GGA-373140 isocitrate <=> citrate TAS Gallus gallus 16947 R-GGA-70971 https://reactome.org/PathwayBrowser/#/R-GGA-70971 ACO2 isomerizes citrate IEA Gallus gallus 16947 R-GGA-70975 https://reactome.org/PathwayBrowser/#/R-GGA-70975 CS acetylates OA to citrate IEA Gallus gallus 16947 R-GGA-75849 https://reactome.org/PathwayBrowser/#/R-GGA-75849 SLC25A1 exchanges CIT and MAL IEA Gallus gallus 16947 R-HSA-70971 https://reactome.org/PathwayBrowser/#/R-HSA-70971 ACO2 isomerizes citrate TAS Homo sapiens 16947 R-HSA-70975 https://reactome.org/PathwayBrowser/#/R-HSA-70975 CS acetylates OA to citrate TAS Homo sapiens 16947 R-HSA-75849 https://reactome.org/PathwayBrowser/#/R-HSA-75849 SLC25A1 exchanges CIT and MAL TAS Homo sapiens 16947 R-MMU-70971 https://reactome.org/PathwayBrowser/#/R-MMU-70971 ACO2 isomerizes citrate IEA Mus musculus 16947 R-MMU-70975 https://reactome.org/PathwayBrowser/#/R-MMU-70975 CS acetylates OA to citrate IEA Mus musculus 16947 R-MMU-75849 https://reactome.org/PathwayBrowser/#/R-MMU-75849 SLC25A1 exchanges CIT and MAL IEA Mus musculus 16947 R-PFA-70975 https://reactome.org/PathwayBrowser/#/R-PFA-70975 CS acetylates OA to citrate IEA Plasmodium falciparum 16947 R-RNO-70971 https://reactome.org/PathwayBrowser/#/R-RNO-70971 ACO2 isomerizes citrate IEA Rattus norvegicus 16947 R-RNO-70975 https://reactome.org/PathwayBrowser/#/R-RNO-70975 CS acetylates OA to citrate IEA Rattus norvegicus 16947 R-RNO-75849 https://reactome.org/PathwayBrowser/#/R-RNO-75849 SLC25A1 exchanges CIT and MAL IEA Rattus norvegicus 16947 R-SCE-70971 https://reactome.org/PathwayBrowser/#/R-SCE-70971 ACO2 isomerizes citrate IEA Saccharomyces cerevisiae 16947 R-SCE-70975 https://reactome.org/PathwayBrowser/#/R-SCE-70975 CS acetylates OA to citrate IEA Saccharomyces cerevisiae 16947 R-SCE-75849 https://reactome.org/PathwayBrowser/#/R-SCE-75849 SLC25A1 exchanges CIT and MAL IEA Saccharomyces cerevisiae 16947 R-SPO-70971 https://reactome.org/PathwayBrowser/#/R-SPO-70971 ACO2 isomerizes citrate IEA Schizosaccharomyces pombe 16947 R-SPO-70975 https://reactome.org/PathwayBrowser/#/R-SPO-70975 CS acetylates OA to citrate IEA Schizosaccharomyces pombe 16947 R-SPO-75849 https://reactome.org/PathwayBrowser/#/R-SPO-75849 SLC25A1 exchanges CIT and MAL IEA Schizosaccharomyces pombe 16947 R-SSC-70971 https://reactome.org/PathwayBrowser/#/R-SSC-70971 ACO2 isomerizes citrate IEA Sus scrofa 16947 R-SSC-70975 https://reactome.org/PathwayBrowser/#/R-SSC-70975 CS acetylates OA to citrate IEA Sus scrofa 16947 R-SSC-75849 https://reactome.org/PathwayBrowser/#/R-SSC-75849 SLC25A1 exchanges CIT and MAL IEA Sus scrofa 16947 R-XTR-70971 https://reactome.org/PathwayBrowser/#/R-XTR-70971 ACO2 isomerizes citrate IEA Xenopus tropicalis 16947 R-XTR-70975 https://reactome.org/PathwayBrowser/#/R-XTR-70975 CS acetylates OA to citrate IEA Xenopus tropicalis 16947 R-XTR-75849 https://reactome.org/PathwayBrowser/#/R-XTR-75849 SLC25A1 exchanges CIT and MAL IEA Xenopus tropicalis 16953 R-BTA-5693783 https://reactome.org/PathwayBrowser/#/R-BTA-5693783 NAALADases hydrolyse NAAG IEA Bos taurus 16953 R-CEL-5693783 https://reactome.org/PathwayBrowser/#/R-CEL-5693783 NAALADases hydrolyse NAAG IEA Caenorhabditis elegans 16953 R-CFA-5693783 https://reactome.org/PathwayBrowser/#/R-CFA-5693783 NAALADases hydrolyse NAAG IEA Canis familiaris 16953 R-DRE-5693783 https://reactome.org/PathwayBrowser/#/R-DRE-5693783 NAALADases hydrolyse NAAG IEA Danio rerio 16953 R-GGA-5693783 https://reactome.org/PathwayBrowser/#/R-GGA-5693783 NAALADases hydrolyse NAAG IEA Gallus gallus 16953 R-HSA-5693783 https://reactome.org/PathwayBrowser/#/R-HSA-5693783 NAALADases hydrolyse NAAG TAS Homo sapiens 16953 R-MMU-5693783 https://reactome.org/PathwayBrowser/#/R-MMU-5693783 NAALADases hydrolyse NAAG IEA Mus musculus 16953 R-RNO-5693783 https://reactome.org/PathwayBrowser/#/R-RNO-5693783 NAALADases hydrolyse NAAG IEA Rattus norvegicus 16953 R-SCE-5693783 https://reactome.org/PathwayBrowser/#/R-SCE-5693783 NAALADases hydrolyse NAAG IEA Saccharomyces cerevisiae 16953 R-SPO-5693783 https://reactome.org/PathwayBrowser/#/R-SPO-5693783 NAALADases hydrolyse NAAG IEA Schizosaccharomyces pombe 16953 R-SSC-5693783 https://reactome.org/PathwayBrowser/#/R-SSC-5693783 NAALADases hydrolyse NAAG IEA Sus scrofa 16953 R-XTR-5693783 https://reactome.org/PathwayBrowser/#/R-XTR-5693783 NAALADases hydrolyse NAAG IEA Xenopus tropicalis 16955 R-BTA-6787623 https://reactome.org/PathwayBrowser/#/R-BTA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Bos taurus 16955 R-BTA-6787632 https://reactome.org/PathwayBrowser/#/R-BTA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Bos taurus 16955 R-CEL-6787623 https://reactome.org/PathwayBrowser/#/R-CEL-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Caenorhabditis elegans 16955 R-CEL-6787632 https://reactome.org/PathwayBrowser/#/R-CEL-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Caenorhabditis elegans 16955 R-CFA-6787623 https://reactome.org/PathwayBrowser/#/R-CFA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Canis familiaris 16955 R-CFA-6787632 https://reactome.org/PathwayBrowser/#/R-CFA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Canis familiaris 16955 R-DDI-6787623 https://reactome.org/PathwayBrowser/#/R-DDI-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Dictyostelium discoideum 16955 R-DDI-6787632 https://reactome.org/PathwayBrowser/#/R-DDI-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Dictyostelium discoideum 16955 R-DME-6787623 https://reactome.org/PathwayBrowser/#/R-DME-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Drosophila melanogaster 16955 R-DME-6787632 https://reactome.org/PathwayBrowser/#/R-DME-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Drosophila melanogaster 16955 R-DRE-6787623 https://reactome.org/PathwayBrowser/#/R-DRE-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Danio rerio 16955 R-GGA-6787623 https://reactome.org/PathwayBrowser/#/R-GGA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Gallus gallus 16955 R-GGA-6787632 https://reactome.org/PathwayBrowser/#/R-GGA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Gallus gallus 16955 R-HSA-6787623 https://reactome.org/PathwayBrowser/#/R-HSA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal TAS Homo sapiens 16955 R-HSA-6787632 https://reactome.org/PathwayBrowser/#/R-HSA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan TAS Homo sapiens 16955 R-MMU-6787623 https://reactome.org/PathwayBrowser/#/R-MMU-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Mus musculus 16955 R-MMU-6787632 https://reactome.org/PathwayBrowser/#/R-MMU-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Mus musculus 16955 R-PFA-6787623 https://reactome.org/PathwayBrowser/#/R-PFA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Plasmodium falciparum 16955 R-PFA-6787632 https://reactome.org/PathwayBrowser/#/R-PFA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Plasmodium falciparum 16955 R-RNO-6787623 https://reactome.org/PathwayBrowser/#/R-RNO-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Rattus norvegicus 16955 R-RNO-6787632 https://reactome.org/PathwayBrowser/#/R-RNO-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Rattus norvegicus 16955 R-SSC-6787623 https://reactome.org/PathwayBrowser/#/R-SSC-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Sus scrofa 16955 R-SSC-6787632 https://reactome.org/PathwayBrowser/#/R-SSC-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Sus scrofa 16955 R-XTR-6787623 https://reactome.org/PathwayBrowser/#/R-XTR-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Xenopus tropicalis 16955 R-XTR-6787632 https://reactome.org/PathwayBrowser/#/R-XTR-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Xenopus tropicalis 16958 R-BTA-351987 https://reactome.org/PathwayBrowser/#/R-BTA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Bos taurus 16958 R-BTA-352029 https://reactome.org/PathwayBrowser/#/R-BTA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Bos taurus 16958 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 16958 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 16958 R-CFA-351987 https://reactome.org/PathwayBrowser/#/R-CFA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Canis familiaris 16958 R-CFA-352029 https://reactome.org/PathwayBrowser/#/R-CFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Canis familiaris 16958 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 16958 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 16958 R-DRE-351987 https://reactome.org/PathwayBrowser/#/R-DRE-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Danio rerio 16958 R-DRE-352029 https://reactome.org/PathwayBrowser/#/R-DRE-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Danio rerio 16958 R-GGA-351987 https://reactome.org/PathwayBrowser/#/R-GGA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Gallus gallus 16958 R-GGA-352029 https://reactome.org/PathwayBrowser/#/R-GGA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Gallus gallus 16958 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 16958 R-HSA-351987 https://reactome.org/PathwayBrowser/#/R-HSA-351987 SLC6A6-mediated uptake of taurine and beta-alanine TAS Homo sapiens 16958 R-HSA-352029 https://reactome.org/PathwayBrowser/#/R-HSA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine TAS Homo sapiens 16958 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 16958 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 16958 R-MMU-351987 https://reactome.org/PathwayBrowser/#/R-MMU-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Mus musculus 16958 R-MMU-352029 https://reactome.org/PathwayBrowser/#/R-MMU-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Mus musculus 16958 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 16958 R-PFA-351987 https://reactome.org/PathwayBrowser/#/R-PFA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Plasmodium falciparum 16958 R-PFA-352029 https://reactome.org/PathwayBrowser/#/R-PFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Plasmodium falciparum 16958 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 16958 R-RNO-351987 https://reactome.org/PathwayBrowser/#/R-RNO-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Rattus norvegicus 16958 R-RNO-352029 https://reactome.org/PathwayBrowser/#/R-RNO-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Rattus norvegicus 16958 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 16958 R-SSC-351987 https://reactome.org/PathwayBrowser/#/R-SSC-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Sus scrofa 16958 R-SSC-352029 https://reactome.org/PathwayBrowser/#/R-SSC-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Sus scrofa 16958 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 16958 R-XTR-351987 https://reactome.org/PathwayBrowser/#/R-XTR-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Xenopus tropicalis 16958 R-XTR-352029 https://reactome.org/PathwayBrowser/#/R-XTR-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Xenopus tropicalis 16958 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 16960 R-BTA-5651828 https://reactome.org/PathwayBrowser/#/R-BTA-5651828 PARG dePARylates PARP1,PARP2 IEA Bos taurus 16960 R-DDI-5651828 https://reactome.org/PathwayBrowser/#/R-DDI-5651828 PARG dePARylates PARP1,PARP2 IEA Dictyostelium discoideum 16960 R-DME-5651828 https://reactome.org/PathwayBrowser/#/R-DME-5651828 PARG dePARylates PARP1,PARP2 IEA Drosophila melanogaster 16960 R-GGA-5651828 https://reactome.org/PathwayBrowser/#/R-GGA-5651828 PARG dePARylates PARP1,PARP2 IEA Gallus gallus 16960 R-HSA-5651828 https://reactome.org/PathwayBrowser/#/R-HSA-5651828 PARG dePARylates PARP1,PARP2 TAS Homo sapiens 16960 R-MMU-5651828 https://reactome.org/PathwayBrowser/#/R-MMU-5651828 PARG dePARylates PARP1,PARP2 IEA Mus musculus 16960 R-RNO-5651828 https://reactome.org/PathwayBrowser/#/R-RNO-5651828 PARG dePARylates PARP1,PARP2 IEA Rattus norvegicus 16960 R-SSC-5651828 https://reactome.org/PathwayBrowser/#/R-SSC-5651828 PARG dePARylates PARP1,PARP2 IEA Sus scrofa 16960 R-XTR-5651828 https://reactome.org/PathwayBrowser/#/R-XTR-5651828 PARG dePARylates PARP1,PARP2 IEA Xenopus tropicalis 16962 R-BTA-194023 https://reactome.org/PathwayBrowser/#/R-BTA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Bos taurus 16962 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 16962 R-CFA-194023 https://reactome.org/PathwayBrowser/#/R-CFA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Canis familiaris 16962 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 16962 R-DME-194023 https://reactome.org/PathwayBrowser/#/R-DME-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Drosophila melanogaster 16962 R-DRE-194023 https://reactome.org/PathwayBrowser/#/R-DRE-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Danio rerio 16962 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 16962 R-GGA-194023 https://reactome.org/PathwayBrowser/#/R-GGA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Gallus gallus 16962 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 16962 R-HSA-194023 https://reactome.org/PathwayBrowser/#/R-HSA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR TAS Homo sapiens 16962 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 16962 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 16962 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 16962 R-MMU-194023 https://reactome.org/PathwayBrowser/#/R-MMU-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Mus musculus 16962 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 16962 R-RNO-194023 https://reactome.org/PathwayBrowser/#/R-RNO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Rattus norvegicus 16962 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 16962 R-SPO-194023 https://reactome.org/PathwayBrowser/#/R-SPO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Schizosaccharomyces pombe 16962 R-SSC-194023 https://reactome.org/PathwayBrowser/#/R-SSC-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Sus scrofa 16962 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 16962 R-XTR-194023 https://reactome.org/PathwayBrowser/#/R-XTR-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Xenopus tropicalis 16973 R-BTA-1449687 https://reactome.org/PathwayBrowser/#/R-BTA-1449687 Corticosteroids bind to CBG in blood IEA Bos taurus 16973 R-BTA-193964 https://reactome.org/PathwayBrowser/#/R-BTA-193964 CYP21A2 21-hydroxylates PROG IEA Bos taurus 16973 R-BTA-194017 https://reactome.org/PathwayBrowser/#/R-BTA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Bos taurus 16973 R-BTA-4341025 https://reactome.org/PathwayBrowser/#/R-BTA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Bos taurus 16973 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 16973 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 16973 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 16973 R-BTA-5618099 https://reactome.org/PathwayBrowser/#/R-BTA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Bos taurus 16973 R-CEL-1449687 https://reactome.org/PathwayBrowser/#/R-CEL-1449687 Corticosteroids bind to CBG in blood IEA Caenorhabditis elegans 16973 R-CFA-1449687 https://reactome.org/PathwayBrowser/#/R-CFA-1449687 Corticosteroids bind to CBG in blood IEA Canis familiaris 16973 R-CFA-193964 https://reactome.org/PathwayBrowser/#/R-CFA-193964 CYP21A2 21-hydroxylates PROG IEA Canis familiaris 16973 R-CFA-194017 https://reactome.org/PathwayBrowser/#/R-CFA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Canis familiaris 16973 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 16973 R-CFA-5618099 https://reactome.org/PathwayBrowser/#/R-CFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Canis familiaris 16973 R-DDI-193964 https://reactome.org/PathwayBrowser/#/R-DDI-193964 CYP21A2 21-hydroxylates PROG IEA Dictyostelium discoideum 16973 R-DME-1449687 https://reactome.org/PathwayBrowser/#/R-DME-1449687 Corticosteroids bind to CBG in blood IEA Drosophila melanogaster 16973 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 16973 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 16973 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 16973 R-DME-5618099 https://reactome.org/PathwayBrowser/#/R-DME-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 16973 R-DRE-1449687 https://reactome.org/PathwayBrowser/#/R-DRE-1449687 Corticosteroids bind to CBG in blood IEA Danio rerio 16973 R-DRE-4341025 https://reactome.org/PathwayBrowser/#/R-DRE-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Danio rerio 16973 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 16973 R-DRE-5618099 https://reactome.org/PathwayBrowser/#/R-DRE-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Danio rerio 16973 R-GGA-193964 https://reactome.org/PathwayBrowser/#/R-GGA-193964 CYP21A2 21-hydroxylates PROG IEA Gallus gallus 16973 R-GGA-4341025 https://reactome.org/PathwayBrowser/#/R-GGA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Gallus gallus 16973 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 16973 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 16973 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 16973 R-GGA-5618099 https://reactome.org/PathwayBrowser/#/R-GGA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Gallus gallus 16973 R-HSA-1449687 https://reactome.org/PathwayBrowser/#/R-HSA-1449687 Corticosteroids bind to CBG in blood TAS Homo sapiens 16973 R-HSA-193964 https://reactome.org/PathwayBrowser/#/R-HSA-193964 CYP21A2 21-hydroxylates PROG TAS Homo sapiens 16973 R-HSA-193996 https://reactome.org/PathwayBrowser/#/R-HSA-193996 11DCORST translocates from cytosol to mitochondrial matrix TAS Homo sapiens 16973 R-HSA-194017 https://reactome.org/PathwayBrowser/#/R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST TAS Homo sapiens 16973 R-HSA-4341025 https://reactome.org/PathwayBrowser/#/R-HSA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 TAS Homo sapiens 16973 R-HSA-549493 https://reactome.org/PathwayBrowser/#/R-HSA-549493 Expression of PERIOD-2 IEA Homo sapiens 16973 R-HSA-5600598 https://reactome.org/PathwayBrowser/#/R-HSA-5600598 Defective CYP11B2 does not oxidise 11DCORST TAS Homo sapiens 16973 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 16973 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 16973 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 16973 R-HSA-5618099 https://reactome.org/PathwayBrowser/#/R-HSA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) TAS Homo sapiens 16973 R-HSA-8848804 https://reactome.org/PathwayBrowser/#/R-HSA-8848804 HIF1A,EPAS1 promote PTK6 gene expression TAS Homo sapiens 16973 R-HSA-8856930 https://reactome.org/PathwayBrowser/#/R-HSA-8856930 EPAS1 (HIF2A) and activated NR3C1 (GCR) bind PTK6 gene TAS Homo sapiens 16973 R-HSA-8939900 https://reactome.org/PathwayBrowser/#/R-HSA-8939900 RUNX2 gene expression from proximal (P2) promoter is stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and inhibited by ESRRA:PPARG1CB and DEXA:NR3C1 IEA Homo sapiens 16973 R-HSA-9009085 https://reactome.org/PathwayBrowser/#/R-HSA-9009085 DEXA:NR3C1 complex binds RUNX2 gene proximal promoter IEA Homo sapiens 16973 R-HSA-9625693 https://reactome.org/PathwayBrowser/#/R-HSA-9625693 TRIM63 gene expression is stimulated by FOXO1 and FOXO3 IEA Homo sapiens 16973 R-HSA-9625699 https://reactome.org/PathwayBrowser/#/R-HSA-9625699 FOXO1 and NR3C1 bind TRIM63 gene promoter IEA Homo sapiens 16973 R-HSA-9769345 https://reactome.org/PathwayBrowser/#/R-HSA-9769345 Activated glucocorticoid receptor represses NPAS4 gene transcription IEA Homo sapiens 16973 R-HSA-9769347 https://reactome.org/PathwayBrowser/#/R-HSA-9769347 Activated glucocorticoid receptor binds NPAS4 gene promoter IEA Homo sapiens 16973 R-MMU-1449687 https://reactome.org/PathwayBrowser/#/R-MMU-1449687 Corticosteroids bind to CBG in blood IEA Mus musculus 16973 R-MMU-193964 https://reactome.org/PathwayBrowser/#/R-MMU-193964 CYP21A2 21-hydroxylates PROG IEA Mus musculus 16973 R-MMU-194017 https://reactome.org/PathwayBrowser/#/R-MMU-194017 CYP11B2 oxidises 11DCORST to CORST IEA Mus musculus 16973 R-MMU-4341025 https://reactome.org/PathwayBrowser/#/R-MMU-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Mus musculus 16973 R-MMU-549409 https://reactome.org/PathwayBrowser/#/R-MMU-549409 Expression of Period-2 (Per2) TAS Mus musculus 16973 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 16973 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 16973 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 16973 R-MMU-5618099 https://reactome.org/PathwayBrowser/#/R-MMU-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Mus musculus 16973 R-MMU-9009091 https://reactome.org/PathwayBrowser/#/R-MMU-9009091 Nr3c1:DEXA binds Runx2 proximal promoter TAS Mus musculus 16973 R-MMU-9009102 https://reactome.org/PathwayBrowser/#/R-MMU-9009102 Runx2 gene expression from proximal (P2) promoter is stimulated by Runx2-P2 and inhibited by DEXA:Nr3c1 TAS Mus musculus 16973 R-MMU-9625700 https://reactome.org/PathwayBrowser/#/R-MMU-9625700 Foxo1 and Nr3c1 bind Trim63 gene promoter TAS Mus musculus 16973 R-MMU-9625730 https://reactome.org/PathwayBrowser/#/R-MMU-9625730 Trim63 gene expression is activated by Foxo1 and Nr3c1 TAS Mus musculus 16973 R-MMU-9769703 https://reactome.org/PathwayBrowser/#/R-MMU-9769703 Activated glucocorticoid receptor binds Npas4 gene promoter TAS Mus musculus 16973 R-MMU-9769713 https://reactome.org/PathwayBrowser/#/R-MMU-9769713 Activated glucocorticoid receptor represses Npas4 gene transcription TAS Mus musculus 16973 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 16973 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 16973 R-PFA-5618099 https://reactome.org/PathwayBrowser/#/R-PFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 16973 R-RNO-1449687 https://reactome.org/PathwayBrowser/#/R-RNO-1449687 Corticosteroids bind to CBG in blood IEA Rattus norvegicus 16973 R-RNO-193964 https://reactome.org/PathwayBrowser/#/R-RNO-193964 CYP21A2 21-hydroxylates PROG IEA Rattus norvegicus 16973 R-RNO-194017 https://reactome.org/PathwayBrowser/#/R-RNO-194017 CYP11B2 oxidises 11DCORST to CORST IEA Rattus norvegicus 16973 R-RNO-4341025 https://reactome.org/PathwayBrowser/#/R-RNO-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Rattus norvegicus 16973 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 16973 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 16973 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 16973 R-RNO-5618099 https://reactome.org/PathwayBrowser/#/R-RNO-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Rattus norvegicus 16973 R-SSC-1449687 https://reactome.org/PathwayBrowser/#/R-SSC-1449687 Corticosteroids bind to CBG in blood IEA Sus scrofa 16973 R-SSC-193964 https://reactome.org/PathwayBrowser/#/R-SSC-193964 CYP21A2 21-hydroxylates PROG IEA Sus scrofa 16973 R-SSC-194017 https://reactome.org/PathwayBrowser/#/R-SSC-194017 CYP11B2 oxidises 11DCORST to CORST IEA Sus scrofa 16973 R-SSC-4341025 https://reactome.org/PathwayBrowser/#/R-SSC-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Sus scrofa 16973 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 16973 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 16973 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 16973 R-SSC-5618099 https://reactome.org/PathwayBrowser/#/R-SSC-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Sus scrofa 16973 R-XTR-1449687 https://reactome.org/PathwayBrowser/#/R-XTR-1449687 Corticosteroids bind to CBG in blood IEA Xenopus tropicalis 16973 R-XTR-194017 https://reactome.org/PathwayBrowser/#/R-XTR-194017 CYP11B2 oxidises 11DCORST to CORST IEA Xenopus tropicalis 16973 R-XTR-4341025 https://reactome.org/PathwayBrowser/#/R-XTR-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Xenopus tropicalis 16973 R-XTR-5618099 https://reactome.org/PathwayBrowser/#/R-XTR-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 16975 R-BTA-1482548 https://reactome.org/PathwayBrowser/#/R-BTA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Bos taurus 16975 R-BTA-1482604 https://reactome.org/PathwayBrowser/#/R-BTA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Bos taurus 16975 R-BTA-1482656 https://reactome.org/PathwayBrowser/#/R-BTA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Bos taurus 16975 R-BTA-1482679 https://reactome.org/PathwayBrowser/#/R-BTA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Bos taurus 16975 R-BTA-1482695 https://reactome.org/PathwayBrowser/#/R-BTA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Bos taurus 16975 R-BTA-1602446 https://reactome.org/PathwayBrowser/#/R-BTA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Bos taurus 16975 R-BTA-549112 https://reactome.org/PathwayBrowser/#/R-BTA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Bos taurus 16975 R-BTA-6786650 https://reactome.org/PathwayBrowser/#/R-BTA-6786650 DDHD1,2 hydrolyse PA IEA Bos taurus 16975 R-BTA-75885 https://reactome.org/PathwayBrowser/#/R-BTA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Bos taurus 16975 R-BTA-75886 https://reactome.org/PathwayBrowser/#/R-BTA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Bos taurus 16975 R-CEL-1482548 https://reactome.org/PathwayBrowser/#/R-CEL-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Caenorhabditis elegans 16975 R-CEL-1482604 https://reactome.org/PathwayBrowser/#/R-CEL-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Caenorhabditis elegans 16975 R-CEL-1482656 https://reactome.org/PathwayBrowser/#/R-CEL-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Caenorhabditis elegans 16975 R-CEL-1482679 https://reactome.org/PathwayBrowser/#/R-CEL-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Caenorhabditis elegans 16975 R-CEL-1482695 https://reactome.org/PathwayBrowser/#/R-CEL-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Caenorhabditis elegans 16975 R-CEL-1602446 https://reactome.org/PathwayBrowser/#/R-CEL-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Caenorhabditis elegans 16975 R-CEL-549112 https://reactome.org/PathwayBrowser/#/R-CEL-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Caenorhabditis elegans 16975 R-CEL-75885 https://reactome.org/PathwayBrowser/#/R-CEL-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Caenorhabditis elegans 16975 R-CEL-75886 https://reactome.org/PathwayBrowser/#/R-CEL-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Caenorhabditis elegans 16975 R-CFA-1482548 https://reactome.org/PathwayBrowser/#/R-CFA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Canis familiaris 16975 R-CFA-1482604 https://reactome.org/PathwayBrowser/#/R-CFA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Canis familiaris 16975 R-CFA-1482656 https://reactome.org/PathwayBrowser/#/R-CFA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Canis familiaris 16975 R-CFA-1482695 https://reactome.org/PathwayBrowser/#/R-CFA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Canis familiaris 16975 R-CFA-1602446 https://reactome.org/PathwayBrowser/#/R-CFA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Canis familiaris 16975 R-CFA-549112 https://reactome.org/PathwayBrowser/#/R-CFA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Canis familiaris 16975 R-CFA-6786650 https://reactome.org/PathwayBrowser/#/R-CFA-6786650 DDHD1,2 hydrolyse PA IEA Canis familiaris 16975 R-CFA-75885 https://reactome.org/PathwayBrowser/#/R-CFA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Canis familiaris 16975 R-CFA-75886 https://reactome.org/PathwayBrowser/#/R-CFA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Canis familiaris 16975 R-DDI-1482548 https://reactome.org/PathwayBrowser/#/R-DDI-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Dictyostelium discoideum 16975 R-DDI-549112 https://reactome.org/PathwayBrowser/#/R-DDI-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Dictyostelium discoideum 16975 R-DDI-6786650 https://reactome.org/PathwayBrowser/#/R-DDI-6786650 DDHD1,2 hydrolyse PA IEA Dictyostelium discoideum 16975 R-DDI-75885 https://reactome.org/PathwayBrowser/#/R-DDI-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Dictyostelium discoideum 16975 R-DME-1482604 https://reactome.org/PathwayBrowser/#/R-DME-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Drosophila melanogaster 16975 R-DME-1482656 https://reactome.org/PathwayBrowser/#/R-DME-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Drosophila melanogaster 16975 R-DME-1482679 https://reactome.org/PathwayBrowser/#/R-DME-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Drosophila melanogaster 16975 R-DME-1482695 https://reactome.org/PathwayBrowser/#/R-DME-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Drosophila melanogaster 16975 R-DME-1602446 https://reactome.org/PathwayBrowser/#/R-DME-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Drosophila melanogaster 16975 R-DME-549112 https://reactome.org/PathwayBrowser/#/R-DME-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Drosophila melanogaster 16975 R-DME-75885 https://reactome.org/PathwayBrowser/#/R-DME-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Drosophila melanogaster 16975 R-DME-75886 https://reactome.org/PathwayBrowser/#/R-DME-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Drosophila melanogaster 16975 R-DRE-1482604 https://reactome.org/PathwayBrowser/#/R-DRE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Danio rerio 16975 R-DRE-1482656 https://reactome.org/PathwayBrowser/#/R-DRE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Danio rerio 16975 R-DRE-1482695 https://reactome.org/PathwayBrowser/#/R-DRE-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Danio rerio 16975 R-DRE-1602446 https://reactome.org/PathwayBrowser/#/R-DRE-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Danio rerio 16975 R-DRE-549112 https://reactome.org/PathwayBrowser/#/R-DRE-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Danio rerio 16975 R-DRE-75885 https://reactome.org/PathwayBrowser/#/R-DRE-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Danio rerio 16975 R-GGA-1482548 https://reactome.org/PathwayBrowser/#/R-GGA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Gallus gallus 16975 R-GGA-1482604 https://reactome.org/PathwayBrowser/#/R-GGA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Gallus gallus 16975 R-GGA-1482656 https://reactome.org/PathwayBrowser/#/R-GGA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Gallus gallus 16975 R-GGA-1482679 https://reactome.org/PathwayBrowser/#/R-GGA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Gallus gallus 16975 R-GGA-1482695 https://reactome.org/PathwayBrowser/#/R-GGA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Gallus gallus 16975 R-GGA-1602446 https://reactome.org/PathwayBrowser/#/R-GGA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Gallus gallus 16975 R-GGA-549112 https://reactome.org/PathwayBrowser/#/R-GGA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Gallus gallus 16975 R-GGA-6786650 https://reactome.org/PathwayBrowser/#/R-GGA-6786650 DDHD1,2 hydrolyse PA IEA Gallus gallus 16975 R-GGA-75885 https://reactome.org/PathwayBrowser/#/R-GGA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Gallus gallus 16975 R-GGA-75886 https://reactome.org/PathwayBrowser/#/R-GGA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Gallus gallus 16975 R-HSA-1482548 https://reactome.org/PathwayBrowser/#/R-HSA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) TAS Homo sapiens 16975 R-HSA-1482604 https://reactome.org/PathwayBrowser/#/R-HSA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) TAS Homo sapiens 16975 R-HSA-1482656 https://reactome.org/PathwayBrowser/#/R-HSA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] TAS Homo sapiens 16975 R-HSA-1482679 https://reactome.org/PathwayBrowser/#/R-HSA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A TAS Homo sapiens 16975 R-HSA-1482695 https://reactome.org/PathwayBrowser/#/R-HSA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) TAS Homo sapiens 16975 R-HSA-1602446 https://reactome.org/PathwayBrowser/#/R-HSA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] TAS Homo sapiens 16975 R-HSA-549112 https://reactome.org/PathwayBrowser/#/R-HSA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 TAS Homo sapiens 16975 R-HSA-6786650 https://reactome.org/PathwayBrowser/#/R-HSA-6786650 DDHD1,2 hydrolyse PA TAS Homo sapiens 16975 R-HSA-75885 https://reactome.org/PathwayBrowser/#/R-HSA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) TAS Homo sapiens 16975 R-HSA-75886 https://reactome.org/PathwayBrowser/#/R-HSA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] TAS Homo sapiens 16975 R-MMU-1482548 https://reactome.org/PathwayBrowser/#/R-MMU-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Mus musculus 16975 R-MMU-1482604 https://reactome.org/PathwayBrowser/#/R-MMU-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Mus musculus 16975 R-MMU-1482656 https://reactome.org/PathwayBrowser/#/R-MMU-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Mus musculus 16975 R-MMU-1482679 https://reactome.org/PathwayBrowser/#/R-MMU-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Mus musculus 16975 R-MMU-1482695 https://reactome.org/PathwayBrowser/#/R-MMU-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Mus musculus 16975 R-MMU-1602446 https://reactome.org/PathwayBrowser/#/R-MMU-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Mus musculus 16975 R-MMU-549112 https://reactome.org/PathwayBrowser/#/R-MMU-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Mus musculus 16975 R-MMU-6786650 https://reactome.org/PathwayBrowser/#/R-MMU-6786650 DDHD1,2 hydrolyse PA IEA Mus musculus 16975 R-MMU-75885 https://reactome.org/PathwayBrowser/#/R-MMU-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Mus musculus 16975 R-MMU-75886 https://reactome.org/PathwayBrowser/#/R-MMU-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Mus musculus 16975 R-PFA-6786650 https://reactome.org/PathwayBrowser/#/R-PFA-6786650 DDHD1,2 hydrolyse PA IEA Plasmodium falciparum 16975 R-PFA-75885 https://reactome.org/PathwayBrowser/#/R-PFA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Plasmodium falciparum 16975 R-RNO-1482548 https://reactome.org/PathwayBrowser/#/R-RNO-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Rattus norvegicus 16975 R-RNO-1482604 https://reactome.org/PathwayBrowser/#/R-RNO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Rattus norvegicus 16975 R-RNO-1482656 https://reactome.org/PathwayBrowser/#/R-RNO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Rattus norvegicus 16975 R-RNO-1482679 https://reactome.org/PathwayBrowser/#/R-RNO-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Rattus norvegicus 16975 R-RNO-1482695 https://reactome.org/PathwayBrowser/#/R-RNO-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Rattus norvegicus 16975 R-RNO-1602446 https://reactome.org/PathwayBrowser/#/R-RNO-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Rattus norvegicus 16975 R-RNO-549112 https://reactome.org/PathwayBrowser/#/R-RNO-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Rattus norvegicus 16975 R-RNO-6786650 https://reactome.org/PathwayBrowser/#/R-RNO-6786650 DDHD1,2 hydrolyse PA IEA Rattus norvegicus 16975 R-RNO-75885 https://reactome.org/PathwayBrowser/#/R-RNO-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Rattus norvegicus 16975 R-RNO-75886 https://reactome.org/PathwayBrowser/#/R-RNO-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Rattus norvegicus 16975 R-SCE-1482604 https://reactome.org/PathwayBrowser/#/R-SCE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Saccharomyces cerevisiae 16975 R-SCE-1482656 https://reactome.org/PathwayBrowser/#/R-SCE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Saccharomyces cerevisiae 16975 R-SCE-6786650 https://reactome.org/PathwayBrowser/#/R-SCE-6786650 DDHD1,2 hydrolyse PA IEA Saccharomyces cerevisiae 16975 R-SCE-75885 https://reactome.org/PathwayBrowser/#/R-SCE-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Saccharomyces cerevisiae 16975 R-SPO-1482604 https://reactome.org/PathwayBrowser/#/R-SPO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Schizosaccharomyces pombe 16975 R-SPO-1482656 https://reactome.org/PathwayBrowser/#/R-SPO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Schizosaccharomyces pombe 16975 R-SPO-6786650 https://reactome.org/PathwayBrowser/#/R-SPO-6786650 DDHD1,2 hydrolyse PA IEA Schizosaccharomyces pombe 16975 R-SPO-75885 https://reactome.org/PathwayBrowser/#/R-SPO-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Schizosaccharomyces pombe 16975 R-SSC-1482548 https://reactome.org/PathwayBrowser/#/R-SSC-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Sus scrofa 16975 R-SSC-1482604 https://reactome.org/PathwayBrowser/#/R-SSC-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Sus scrofa 16975 R-SSC-1482656 https://reactome.org/PathwayBrowser/#/R-SSC-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Sus scrofa 16975 R-SSC-1482679 https://reactome.org/PathwayBrowser/#/R-SSC-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Sus scrofa 16975 R-SSC-1482695 https://reactome.org/PathwayBrowser/#/R-SSC-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Sus scrofa 16975 R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa 16975 R-SSC-549112 https://reactome.org/PathwayBrowser/#/R-SSC-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Sus scrofa 16975 R-SSC-6786650 https://reactome.org/PathwayBrowser/#/R-SSC-6786650 DDHD1,2 hydrolyse PA IEA Sus scrofa 16975 R-SSC-75885 https://reactome.org/PathwayBrowser/#/R-SSC-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Sus scrofa 16975 R-SSC-75886 https://reactome.org/PathwayBrowser/#/R-SSC-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Sus scrofa 16975 R-XTR-1482604 https://reactome.org/PathwayBrowser/#/R-XTR-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Xenopus tropicalis 16975 R-XTR-1482656 https://reactome.org/PathwayBrowser/#/R-XTR-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Xenopus tropicalis 16975 R-XTR-1482679 https://reactome.org/PathwayBrowser/#/R-XTR-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Xenopus tropicalis 16975 R-XTR-1482695 https://reactome.org/PathwayBrowser/#/R-XTR-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Xenopus tropicalis 16975 R-XTR-1602446 https://reactome.org/PathwayBrowser/#/R-XTR-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Xenopus tropicalis 16975 R-XTR-549112 https://reactome.org/PathwayBrowser/#/R-XTR-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Xenopus tropicalis 16975 R-XTR-6786650 https://reactome.org/PathwayBrowser/#/R-XTR-6786650 DDHD1,2 hydrolyse PA IEA Xenopus tropicalis 16975 R-XTR-75885 https://reactome.org/PathwayBrowser/#/R-XTR-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Xenopus tropicalis 16975 R-XTR-75886 https://reactome.org/PathwayBrowser/#/R-XTR-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Xenopus tropicalis 16978 R-BTA-266046 https://reactome.org/PathwayBrowser/#/R-BTA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Bos taurus 16978 R-BTA-266050 https://reactome.org/PathwayBrowser/#/R-BTA-266050 LTA4 is converted to LTC4 by LTC4S IEA Bos taurus 16978 R-BTA-266070 https://reactome.org/PathwayBrowser/#/R-BTA-266070 LTC4 is exported from the cytosol by ABCC1 IEA Bos taurus 16978 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 16978 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 16978 R-BTA-391937 https://reactome.org/PathwayBrowser/#/R-BTA-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Bos taurus 16978 R-BTA-391943 https://reactome.org/PathwayBrowser/#/R-BTA-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Bos taurus 16978 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 16978 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 16978 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 16978 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 16978 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 16978 R-CEL-266046 https://reactome.org/PathwayBrowser/#/R-CEL-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Caenorhabditis elegans 16978 R-CEL-266070 https://reactome.org/PathwayBrowser/#/R-CEL-266070 LTC4 is exported from the cytosol by ABCC1 IEA Caenorhabditis elegans 16978 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 16978 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 16978 R-CEL-391937 https://reactome.org/PathwayBrowser/#/R-CEL-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Caenorhabditis elegans 16978 R-CEL-391943 https://reactome.org/PathwayBrowser/#/R-CEL-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 16978 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 16978 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 16978 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 16978 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 16978 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 16978 R-CFA-266046 https://reactome.org/PathwayBrowser/#/R-CFA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Canis familiaris 16978 R-CFA-266050 https://reactome.org/PathwayBrowser/#/R-CFA-266050 LTA4 is converted to LTC4 by LTC4S IEA Canis familiaris 16978 R-CFA-266070 https://reactome.org/PathwayBrowser/#/R-CFA-266070 LTC4 is exported from the cytosol by ABCC1 IEA Canis familiaris 16978 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 16978 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 16978 R-CFA-391937 https://reactome.org/PathwayBrowser/#/R-CFA-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Canis familiaris 16978 R-CFA-391943 https://reactome.org/PathwayBrowser/#/R-CFA-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Canis familiaris 16978 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 16978 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 16978 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 16978 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 16978 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 16978 R-DDI-266050 https://reactome.org/PathwayBrowser/#/R-DDI-266050 LTA4 is converted to LTC4 by LTC4S IEA Dictyostelium discoideum 16978 R-DDI-266070 https://reactome.org/PathwayBrowser/#/R-DDI-266070 LTC4 is exported from the cytosol by ABCC1 IEA Dictyostelium discoideum 16978 R-DME-266046 https://reactome.org/PathwayBrowser/#/R-DME-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Drosophila melanogaster 16978 R-DME-266070 https://reactome.org/PathwayBrowser/#/R-DME-266070 LTC4 is exported from the cytosol by ABCC1 IEA Drosophila melanogaster 16978 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 16978 R-DME-391943 https://reactome.org/PathwayBrowser/#/R-DME-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 16978 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 16978 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 16978 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 16978 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 16978 R-DRE-391943 https://reactome.org/PathwayBrowser/#/R-DRE-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Danio rerio 16978 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 16978 R-GGA-266046 https://reactome.org/PathwayBrowser/#/R-GGA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Gallus gallus 16978 R-GGA-266050 https://reactome.org/PathwayBrowser/#/R-GGA-266050 LTA4 is converted to LTC4 by LTC4S IEA Gallus gallus 16978 R-GGA-266070 https://reactome.org/PathwayBrowser/#/R-GGA-266070 LTC4 is exported from the cytosol by ABCC1 IEA Gallus gallus 16978 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 16978 R-GGA-391943 https://reactome.org/PathwayBrowser/#/R-GGA-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Gallus gallus 16978 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 16978 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 16978 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 16978 R-HSA-266046 https://reactome.org/PathwayBrowser/#/R-HSA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 TAS Homo sapiens 16978 R-HSA-266050 https://reactome.org/PathwayBrowser/#/R-HSA-266050 LTA4 is converted to LTC4 by LTC4S TAS Homo sapiens 16978 R-HSA-266070 https://reactome.org/PathwayBrowser/#/R-HSA-266070 LTC4 is exported from the cytosol by ABCC1 TAS Homo sapiens 16978 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 16978 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 16978 R-HSA-391937 https://reactome.org/PathwayBrowser/#/R-HSA-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes TAS Homo sapiens 16978 R-HSA-391943 https://reactome.org/PathwayBrowser/#/R-HSA-391943 CYSLT2 binds LTC4,LTD4,LTE4 TAS Homo sapiens 16978 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 16978 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 16978 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 16978 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 16978 R-HSA-9664306 https://reactome.org/PathwayBrowser/#/R-HSA-9664306 LTC4 binds CyslTR1,2 TAS Homo sapiens 16978 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 16978 R-MMU-266046 https://reactome.org/PathwayBrowser/#/R-MMU-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Mus musculus 16978 R-MMU-266050 https://reactome.org/PathwayBrowser/#/R-MMU-266050 LTA4 is converted to LTC4 by LTC4S IEA Mus musculus 16978 R-MMU-266070 https://reactome.org/PathwayBrowser/#/R-MMU-266070 LTC4 is exported from the cytosol by ABCC1 IEA Mus musculus 16978 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 16978 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 16978 R-MMU-391937 https://reactome.org/PathwayBrowser/#/R-MMU-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Mus musculus 16978 R-MMU-391943 https://reactome.org/PathwayBrowser/#/R-MMU-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Mus musculus 16978 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 16978 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 16978 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 16978 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 16978 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 16978 R-RNO-266046 https://reactome.org/PathwayBrowser/#/R-RNO-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Rattus norvegicus 16978 R-RNO-266050 https://reactome.org/PathwayBrowser/#/R-RNO-266050 LTA4 is converted to LTC4 by LTC4S IEA Rattus norvegicus 16978 R-RNO-266070 https://reactome.org/PathwayBrowser/#/R-RNO-266070 LTC4 is exported from the cytosol by ABCC1 IEA Rattus norvegicus 16978 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 16978 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 16978 R-RNO-391937 https://reactome.org/PathwayBrowser/#/R-RNO-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Rattus norvegicus 16978 R-RNO-391943 https://reactome.org/PathwayBrowser/#/R-RNO-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 16978 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 16978 R-SCE-266046 https://reactome.org/PathwayBrowser/#/R-SCE-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Saccharomyces cerevisiae 16978 R-SCE-266070 https://reactome.org/PathwayBrowser/#/R-SCE-266070 LTC4 is exported from the cytosol by ABCC1 IEA Saccharomyces cerevisiae 16978 R-SPO-266046 https://reactome.org/PathwayBrowser/#/R-SPO-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Schizosaccharomyces pombe 16978 R-SPO-266070 https://reactome.org/PathwayBrowser/#/R-SPO-266070 LTC4 is exported from the cytosol by ABCC1 IEA Schizosaccharomyces pombe 16978 R-SSC-266046 https://reactome.org/PathwayBrowser/#/R-SSC-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Sus scrofa 16978 R-SSC-266050 https://reactome.org/PathwayBrowser/#/R-SSC-266050 LTA4 is converted to LTC4 by LTC4S IEA Sus scrofa 16978 R-SSC-266070 https://reactome.org/PathwayBrowser/#/R-SSC-266070 LTC4 is exported from the cytosol by ABCC1 IEA Sus scrofa 16978 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 16978 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 16978 R-SSC-391937 https://reactome.org/PathwayBrowser/#/R-SSC-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Sus scrofa 16978 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 16978 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 16978 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 16978 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 16978 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 16978 R-XTR-266050 https://reactome.org/PathwayBrowser/#/R-XTR-266050 LTA4 is converted to LTC4 by LTC4S IEA Xenopus tropicalis 16978 R-XTR-266070 https://reactome.org/PathwayBrowser/#/R-XTR-266070 LTC4 is exported from the cytosol by ABCC1 IEA Xenopus tropicalis 16978 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 16991 R-BTA-3204303 https://reactome.org/PathwayBrowser/#/R-BTA-3204303 MRE11 binds cytosolic DNA IEA Bos taurus 16991 R-CEL-3204303 https://reactome.org/PathwayBrowser/#/R-CEL-3204303 MRE11 binds cytosolic DNA IEA Caenorhabditis elegans 16991 R-CFA-3204303 https://reactome.org/PathwayBrowser/#/R-CFA-3204303 MRE11 binds cytosolic DNA IEA Canis familiaris 16991 R-DDI-3204303 https://reactome.org/PathwayBrowser/#/R-DDI-3204303 MRE11 binds cytosolic DNA IEA Dictyostelium discoideum 16991 R-DME-3204303 https://reactome.org/PathwayBrowser/#/R-DME-3204303 MRE11 binds cytosolic DNA IEA Drosophila melanogaster 16991 R-ECO-9750080 https://reactome.org/PathwayBrowser/#/R-ECO-9750080 Lomustine produces interstrand crosslinks in E. coli DNA TAS Escherichia coli 16991 R-ECO-9750081 https://reactome.org/PathwayBrowser/#/R-ECO-9750081 Carmustine produces interstrand crosslinks in E. coli DNA TAS Escherichia coli 16991 R-GGA-3204303 https://reactome.org/PathwayBrowser/#/R-GGA-3204303 MRE11 binds cytosolic DNA IEA Gallus gallus 16991 R-GGA-353426 https://reactome.org/PathwayBrowser/#/R-GGA-353426 TDG glycosylase mediated recognition and binding of thymine opposite guanine TAS Gallus gallus 16991 R-GGA-353472 https://reactome.org/PathwayBrowser/#/R-GGA-353472 Displacement of DNA glycosylase and endonucleolytic cleavage by DNA-lyase TAS Gallus gallus 16991 R-GGA-353481 https://reactome.org/PathwayBrowser/#/R-GGA-353481 5-methylcytosine G/T mismatch specific DNA glycosylase mediated recognition and binding of thymine opposite guanine at CpG sequences TAS Gallus gallus 16991 R-GGA-353484 https://reactome.org/PathwayBrowser/#/R-GGA-353484 Uracil glycosylase mediated recognition and binding of uracil opposite guanine TAS Gallus gallus 16991 R-HSA-110156 https://reactome.org/PathwayBrowser/#/R-HSA-110156 UNG glycosylase mediated recognition and binding of an uracil opposite to a guanine TAS Homo sapiens 16991 R-HSA-110157 https://reactome.org/PathwayBrowser/#/R-HSA-110157 UNG glycosylase mediated recognition and binding of a 5-hydroxyuracil opposite to a guanine TAS Homo sapiens 16991 R-HSA-110158 https://reactome.org/PathwayBrowser/#/R-HSA-110158 TDG glycosylase mediated recognition and binding of a thymine opposite to a guanine TAS Homo sapiens 16991 R-HSA-110159 https://reactome.org/PathwayBrowser/#/R-HSA-110159 TDG glycosylase mediated recognition and binding of an uracil opposite to a guanine TAS Homo sapiens 16991 R-HSA-110164 https://reactome.org/PathwayBrowser/#/R-HSA-110164 SMUG1 glycosylase mediated recognition and binding of uracil in DNA TAS Homo sapiens 16991 R-HSA-110171 https://reactome.org/PathwayBrowser/#/R-HSA-110171 MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences TAS Homo sapiens 16991 R-HSA-110172 https://reactome.org/PathwayBrowser/#/R-HSA-110172 MBD4 glycosylase mediated recognition and binding of a thymine opposite to a guanine at CpG sequences TAS Homo sapiens 16991 R-HSA-110208 https://reactome.org/PathwayBrowser/#/R-HSA-110208 NTHL1 glycosylase mediated recognition and binding of cytosine glycol TAS Homo sapiens 16991 R-HSA-110210 https://reactome.org/PathwayBrowser/#/R-HSA-110210 TDG glycosylase mediated recognition and binding of an ethenocytosine TAS Homo sapiens 16991 R-HSA-110211 https://reactome.org/PathwayBrowser/#/R-HSA-110211 NTHL1 glycosylase mediated recognition and binding of thymine glycol TAS Homo sapiens 16991 R-HSA-110212 https://reactome.org/PathwayBrowser/#/R-HSA-110212 NTHL1 glycosylase mediated recognition and binding of dihydrouracil TAS Homo sapiens 16991 R-HSA-110213 https://reactome.org/PathwayBrowser/#/R-HSA-110213 NTHL1 glycosylase mediated recognition and binding of formamidopyrimidine (FapyA) TAS Homo sapiens 16991 R-HSA-110215 https://reactome.org/PathwayBrowser/#/R-HSA-110215 Cleavage of uracil by UNG glycosylase TAS Homo sapiens 16991 R-HSA-110217 https://reactome.org/PathwayBrowser/#/R-HSA-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase TAS Homo sapiens 16991 R-HSA-110218 https://reactome.org/PathwayBrowser/#/R-HSA-110218 Cleavage of uracil by TDG glycosylase TAS Homo sapiens 16991 R-HSA-110219 https://reactome.org/PathwayBrowser/#/R-HSA-110219 Cleavage of thymine by TDG glycosylase TAS Homo sapiens 16991 R-HSA-110221 https://reactome.org/PathwayBrowser/#/R-HSA-110221 Cleavage of uracil by SMUG1 glycosylase TAS Homo sapiens 16991 R-HSA-110224 https://reactome.org/PathwayBrowser/#/R-HSA-110224 Cleavage of thymine glycol by NTHL1 glycosylase TAS Homo sapiens 16991 R-HSA-110226 https://reactome.org/PathwayBrowser/#/R-HSA-110226 Cleavage of cytosine glycol by NTHL1 glycosylase TAS Homo sapiens 16991 R-HSA-110227 https://reactome.org/PathwayBrowser/#/R-HSA-110227 Cleavage of dihydrouracil by NTHL1 glycosylase TAS Homo sapiens 16991 R-HSA-110229 https://reactome.org/PathwayBrowser/#/R-HSA-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase TAS Homo sapiens 16991 R-HSA-110231 https://reactome.org/PathwayBrowser/#/R-HSA-110231 Cleavage of uracil by MBD4 glycosylase TAS Homo sapiens 16991 R-HSA-110232 https://reactome.org/PathwayBrowser/#/R-HSA-110232 Cleavage of thymine by MBD4 glycosylase TAS Homo sapiens 16991 R-HSA-110234 https://reactome.org/PathwayBrowser/#/R-HSA-110234 Cleavage of ethenocytosine by TDG glycosylase TAS Homo sapiens 16991 R-HSA-110235 https://reactome.org/PathwayBrowser/#/R-HSA-110235 OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine TAS Homo sapiens 16991 R-HSA-110236 https://reactome.org/PathwayBrowser/#/R-HSA-110236 OGG1 glycosylase mediated recognition and binding of a formamidopyrimidine (FapyG) TAS Homo sapiens 16991 R-HSA-110237 https://reactome.org/PathwayBrowser/#/R-HSA-110237 MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine TAS Homo sapiens 16991 R-HSA-110239 https://reactome.org/PathwayBrowser/#/R-HSA-110239 MPG glycosylase mediated recognition and binding of ethenoadenine TAS Homo sapiens 16991 R-HSA-110240 https://reactome.org/PathwayBrowser/#/R-HSA-110240 MPG glycosylase mediated recognition and binding of hypoxanthine TAS Homo sapiens 16991 R-HSA-110243 https://reactome.org/PathwayBrowser/#/R-HSA-110243 Excision of 8-oxoguanine by OGG1 glycosylase TAS Homo sapiens 16991 R-HSA-110244 https://reactome.org/PathwayBrowser/#/R-HSA-110244 Excision of FapyG by OGG1 glycosylase TAS Homo sapiens 16991 R-HSA-110246 https://reactome.org/PathwayBrowser/#/R-HSA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH TAS Homo sapiens 16991 R-HSA-110248 https://reactome.org/PathwayBrowser/#/R-HSA-110248 Cleavage of 3-methyladenine by MPG glycosylase TAS Homo sapiens 16991 R-HSA-110250 https://reactome.org/PathwayBrowser/#/R-HSA-110250 Cleavage of ethenoadenine by MPG glycosylase TAS Homo sapiens 16991 R-HSA-110251 https://reactome.org/PathwayBrowser/#/R-HSA-110251 Cleavage of hypoxanthine by MPG glycosylase TAS Homo sapiens 16991 R-HSA-110307 https://reactome.org/PathwayBrowser/#/R-HSA-110307 REV1 binds AP-dsDNA TAS Homo sapiens 16991 R-HSA-110308 https://reactome.org/PathwayBrowser/#/R-HSA-110308 REV1 inserts dCMP opposite to AP sites in DNA TAS Homo sapiens 16991 R-HSA-110311 https://reactome.org/PathwayBrowser/#/R-HSA-110311 POLZ extends translesion synthesis TAS Homo sapiens 16991 R-HSA-110316 https://reactome.org/PathwayBrowser/#/R-HSA-110316 POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template TAS Homo sapiens 16991 R-HSA-110317 https://reactome.org/PathwayBrowser/#/R-HSA-110317 Insertion of correct bases opposite the lesion by POLH TAS Homo sapiens 16991 R-HSA-110319 https://reactome.org/PathwayBrowser/#/R-HSA-110319 Elongation by POLH TAS Homo sapiens 16991 R-HSA-110349 https://reactome.org/PathwayBrowser/#/R-HSA-110349 Displacement of UNG glycosylase by APEX1 at the AP site TAS Homo sapiens 16991 R-HSA-110350 https://reactome.org/PathwayBrowser/#/R-HSA-110350 Displacement of TDG glycosylase by APEX1 at the AP site TAS Homo sapiens 16991 R-HSA-110351 https://reactome.org/PathwayBrowser/#/R-HSA-110351 Displacement of SMUG1 glycosylase by APEX1 at the AP site TAS Homo sapiens 16991 R-HSA-110352 https://reactome.org/PathwayBrowser/#/R-HSA-110352 Displacement of NTHL1 glycosylase by APEX1 at the AP site TAS Homo sapiens 16991 R-HSA-110353 https://reactome.org/PathwayBrowser/#/R-HSA-110353 Displacement of MBD4 glycosylase by APEX1 at the AP site TAS Homo sapiens 16991 R-HSA-110354 https://reactome.org/PathwayBrowser/#/R-HSA-110354 Displacement of OGG1 glycosylase by APEX1 at the AP site TAS Homo sapiens 16991 R-HSA-110355 https://reactome.org/PathwayBrowser/#/R-HSA-110355 Displacement of MUTYH glycosylase by APEX1 at the AP site TAS Homo sapiens 16991 R-HSA-110356 https://reactome.org/PathwayBrowser/#/R-HSA-110356 Displacement of MPG glycosylase by APEX1 at the AP site TAS Homo sapiens 16991 R-HSA-110359 https://reactome.org/PathwayBrowser/#/R-HSA-110359 APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site TAS Homo sapiens 16991 R-HSA-110360 https://reactome.org/PathwayBrowser/#/R-HSA-110360 Recruitment of POLB to the AP site TAS Homo sapiens 16991 R-HSA-110363 https://reactome.org/PathwayBrowser/#/R-HSA-110363 FEN1 bound to PCNA and APEX1 cleaves flap ssDNA TAS Homo sapiens 16991 R-HSA-110364 https://reactome.org/PathwayBrowser/#/R-HSA-110364 PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 TAS Homo sapiens 16991 R-HSA-110368 https://reactome.org/PathwayBrowser/#/R-HSA-110368 POLD,POLE-mediated DNA strand displacement synthesis TAS Homo sapiens 16991 R-HSA-110371 https://reactome.org/PathwayBrowser/#/R-HSA-110371 LIG1 binds APEX1 and PCNA at SSB TAS Homo sapiens 16991 R-HSA-110375 https://reactome.org/PathwayBrowser/#/R-HSA-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break TAS Homo sapiens 16991 R-HSA-110376 https://reactome.org/PathwayBrowser/#/R-HSA-110376 Recruitment of LIG3:XRCC1 complex to the site of repair by POLB TAS Homo sapiens 16991 R-HSA-110380 https://reactome.org/PathwayBrowser/#/R-HSA-110380 Dissociation of LIG3:XRCC1 complex from the BER site TAS Homo sapiens 16991 R-HSA-111253 https://reactome.org/PathwayBrowser/#/R-HSA-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site TAS Homo sapiens 16991 R-HSA-112118 https://reactome.org/PathwayBrowser/#/R-HSA-112118 Oxidative demethylation of 1-meA damaged DNA by ALKBH2 TAS Homo sapiens 16991 R-HSA-112120 https://reactome.org/PathwayBrowser/#/R-HSA-112120 Oxidative demethylation of 3-meC damaged DNA by ALKBH2 TAS Homo sapiens 16991 R-HSA-112121 https://reactome.org/PathwayBrowser/#/R-HSA-112121 Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 TAS Homo sapiens 16991 R-HSA-112123 https://reactome.org/PathwayBrowser/#/R-HSA-112123 Oxidative demethylation of 1-meA damaged DNA By ALKBH3 TAS Homo sapiens 16991 R-HSA-112124 https://reactome.org/PathwayBrowser/#/R-HSA-112124 Oxidative demethylation of 3-meC damaged DNA By ALKBH3 TAS Homo sapiens 16991 R-HSA-112125 https://reactome.org/PathwayBrowser/#/R-HSA-112125 Oxidative dealkylation of 1-EtA damaged DNA by ABH3 TAS Homo sapiens 16991 R-HSA-1591234 https://reactome.org/PathwayBrowser/#/R-HSA-1591234 ZBP1 binds cytosolic DNA TAS Homo sapiens 16991 R-HSA-1606324 https://reactome.org/PathwayBrowser/#/R-HSA-1606324 Recruitment TBK1 to dsDNA:ZBP1 followed by its activation IEA Homo sapiens 16991 R-HSA-1606327 https://reactome.org/PathwayBrowser/#/R-HSA-1606327 Phosphorylation and release of IRF3 TAS Homo sapiens 16991 R-HSA-1606345 https://reactome.org/PathwayBrowser/#/R-HSA-1606345 Recruitment of IRF3 to activated ZBP1:TBK1 IEA Homo sapiens 16991 R-HSA-162590 https://reactome.org/PathwayBrowser/#/R-HSA-162590 Import of PIC to the Host Nucleus TAS Homo sapiens 16991 R-HSA-164503 https://reactome.org/PathwayBrowser/#/R-HSA-164503 First strand transfer mediated by Repeated (R) sequence TAS Homo sapiens 16991 R-HSA-164504 https://reactome.org/PathwayBrowser/#/R-HSA-164504 Synthesis of minus strand strong stop DNA (-sssDNA) TAS Homo sapiens 16991 R-HSA-164505 https://reactome.org/PathwayBrowser/#/R-HSA-164505 Synthesis of full-length duplex viral DNA with a discontinuous plus strand TAS Homo sapiens 16991 R-HSA-164506 https://reactome.org/PathwayBrowser/#/R-HSA-164506 Gap repair completes provirus integration TAS Homo sapiens 16991 R-HSA-164512 https://reactome.org/PathwayBrowser/#/R-HSA-164512 Second strand transfer by annealing complementary PBS sequences TAS Homo sapiens 16991 R-HSA-164513 https://reactome.org/PathwayBrowser/#/R-HSA-164513 3' PPT-primed initiation of plus-strand DNA synthesis TAS Homo sapiens 16991 R-HSA-164514 https://reactome.org/PathwayBrowser/#/R-HSA-164514 Integrase binds viral DNA ends TAS Homo sapiens 16991 R-HSA-164519 https://reactome.org/PathwayBrowser/#/R-HSA-164519 RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex TAS Homo sapiens 16991 R-HSA-164520 https://reactome.org/PathwayBrowser/#/R-HSA-164520 Minus strand DNA synthesis resumes TAS Homo sapiens 16991 R-HSA-164522 https://reactome.org/PathwayBrowser/#/R-HSA-164522 Terminal (3' end) cleavage of viral DNA TAS Homo sapiens 16991 R-HSA-164523 https://reactome.org/PathwayBrowser/#/R-HSA-164523 Transesterification to connect viral DNA 3' ends to host DNA 5' ends TAS Homo sapiens 16991 R-HSA-164528 https://reactome.org/PathwayBrowser/#/R-HSA-164528 RNase H-mediated cleavage of the template strand TAS Homo sapiens 16991 R-HSA-164845 https://reactome.org/PathwayBrowser/#/R-HSA-164845 Suicidal integration leading to inverted circle formation TAS Homo sapiens 16991 R-HSA-167097 https://reactome.org/PathwayBrowser/#/R-HSA-167097 HIV Promoter Opening: First Transition IEA Homo sapiens 16991 R-HSA-167098 https://reactome.org/PathwayBrowser/#/R-HSA-167098 Phosphorylation (Ser5) of RNA pol II CTD IEA Homo sapiens 16991 R-HSA-167111 https://reactome.org/PathwayBrowser/#/R-HSA-167111 Extrusion of 5'-end of 30 nt long HIV-1 transcript through the pore in Pol II complex IEA Homo sapiens 16991 R-HSA-167113 https://reactome.org/PathwayBrowser/#/R-HSA-167113 Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition IEA Homo sapiens 16991 R-HSA-167115 https://reactome.org/PathwayBrowser/#/R-HSA-167115 Addition of nucleotides between position +11 and +30 on HIV-1 transcript IEA Homo sapiens 16991 R-HSA-167117 https://reactome.org/PathwayBrowser/#/R-HSA-167117 Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition IEA Homo sapiens 16991 R-HSA-167118 https://reactome.org/PathwayBrowser/#/R-HSA-167118 NTP binds active site of RNA Polymerase II in HIV-1 open pre-initiation complex IEA Homo sapiens 16991 R-HSA-167121 https://reactome.org/PathwayBrowser/#/R-HSA-167121 Addition of the third nucleotide on the nascent HIV-1 transcript IEA Homo sapiens 16991 R-HSA-167128 https://reactome.org/PathwayBrowser/#/R-HSA-167128 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Homo sapiens 16991 R-HSA-167130 https://reactome.org/PathwayBrowser/#/R-HSA-167130 Nucleophillic attack by 3'-hydroxyl oxygen of nascent HIV-1 transcript on the Alpha phosphate of NTP IEA Homo sapiens 16991 R-HSA-167133 https://reactome.org/PathwayBrowser/#/R-HSA-167133 Activation of GT IEA Homo sapiens 16991 R-HSA-167134 https://reactome.org/PathwayBrowser/#/R-HSA-167134 Newly formed phosphodiester bond stabilized and PPi released IEA Homo sapiens 16991 R-HSA-167136 https://reactome.org/PathwayBrowser/#/R-HSA-167136 Addition of nucleotides 5 through 9 on the growing HIV-1 transcript IEA Homo sapiens 16991 R-HSA-167153 https://reactome.org/PathwayBrowser/#/R-HSA-167153 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Homo sapiens 16991 R-HSA-167468 https://reactome.org/PathwayBrowser/#/R-HSA-167468 Abortive HIV-1 Initiation After Second Transition IEA Homo sapiens 16991 R-HSA-167474 https://reactome.org/PathwayBrowser/#/R-HSA-167474 Abortive HIV-1 Initiation Before Second Transition IEA Homo sapiens 16991 R-HSA-167477 https://reactome.org/PathwayBrowser/#/R-HSA-167477 Abortive HIV-1 initiation after formation of the first phosphodiester bond IEA Homo sapiens 16991 R-HSA-167484 https://reactome.org/PathwayBrowser/#/R-HSA-167484 Fall Back to Closed Pre-initiation Complex IEA Homo sapiens 16991 R-HSA-168909 https://reactome.org/PathwayBrowser/#/R-HSA-168909 viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58 bind MAVS TAS Homo sapiens 16991 R-HSA-168910 https://reactome.org/PathwayBrowser/#/R-HSA-168910 RIP1 facilitates IKK complex phosphorylation TAS Homo sapiens 16991 R-HSA-168934 https://reactome.org/PathwayBrowser/#/R-HSA-168934 MAVS interacts with RIPK1 and FADD TAS Homo sapiens 16991 R-HSA-173115 https://reactome.org/PathwayBrowser/#/R-HSA-173115 Formation of Pre-Integration Complex (PIC) TAS Homo sapiens 16991 R-HSA-173769 https://reactome.org/PathwayBrowser/#/R-HSA-173769 RNase H-mediated digestion of tRNA, 3'PPT and cPPT RNA primers TAS Homo sapiens 16991 R-HSA-175108 https://reactome.org/PathwayBrowser/#/R-HSA-175108 Target DNA binding TAS Homo sapiens 16991 R-HSA-175117 https://reactome.org/PathwayBrowser/#/R-HSA-175117 1-LTR circle formation TAS Homo sapiens 16991 R-HSA-175174 https://reactome.org/PathwayBrowser/#/R-HSA-175174 Association of Ku heterodimer with viral DNA ends TAS Homo sapiens 16991 R-HSA-175177 https://reactome.org/PathwayBrowser/#/R-HSA-175177 Association of XRCC4:DNA ligase IV complex with viral DNA ends TAS Homo sapiens 16991 R-HSA-175250 https://reactome.org/PathwayBrowser/#/R-HSA-175250 Suicidal integration leading to smaller circles of viral DNA TAS Homo sapiens 16991 R-HSA-175258 https://reactome.org/PathwayBrowser/#/R-HSA-175258 2-LTR formation due to circularization of viral DNA TAS Homo sapiens 16991 R-HSA-176700 https://reactome.org/PathwayBrowser/#/R-HSA-176700 Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure TAS Homo sapiens 16991 R-HSA-180622 https://reactome.org/PathwayBrowser/#/R-HSA-180622 Vpr binds nucleoporins TAS Homo sapiens 16991 R-HSA-180627 https://reactome.org/PathwayBrowser/#/R-HSA-180627 Interaction of Vpr with importin alpha TAS Homo sapiens 16991 R-HSA-180630 https://reactome.org/PathwayBrowser/#/R-HSA-180630 Association of APOBEC3G with Gag TAS Homo sapiens 16991 R-HSA-180632 https://reactome.org/PathwayBrowser/#/R-HSA-180632 Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand TAS Homo sapiens 16991 R-HSA-180634 https://reactome.org/PathwayBrowser/#/R-HSA-180634 Association of APOBEC3G with single-stranded region of forming HIV-1 minus strand TAS Homo sapiens 16991 R-HSA-1810457 https://reactome.org/PathwayBrowser/#/R-HSA-1810457 ZBP1(DAI) recruits RIP1 and RIP3 TAS Homo sapiens 16991 R-HSA-182795 https://reactome.org/PathwayBrowser/#/R-HSA-182795 RNase H-mediated degradation of the template strand TAS Homo sapiens 16991 R-HSA-182859 https://reactome.org/PathwayBrowser/#/R-HSA-182859 RNase H-mediated degradation of the RNA strand of the -sssDNA:RNA duplex TAS Homo sapiens 16991 R-HSA-182876 https://reactome.org/PathwayBrowser/#/R-HSA-182876 Removal of plus-strand flap and gap closure complete synthesis of linear duplex viral DNA TAS Homo sapiens 16991 R-HSA-1834939 https://reactome.org/PathwayBrowser/#/R-HSA-1834939 STING recruits TBK1 and IRF3 TAS Homo sapiens 16991 R-HSA-1834951 https://reactome.org/PathwayBrowser/#/R-HSA-1834951 IFI16 binds cytosolic dsDNA TAS Homo sapiens 16991 R-HSA-1964482 https://reactome.org/PathwayBrowser/#/R-HSA-1964482 RNA polymerase III transcribes microbial dsDNA to dsRNA TAS Homo sapiens 16991 R-HSA-203901 https://reactome.org/PathwayBrowser/#/R-HSA-203901 Pol II mediated transcription of microRNA genes TAS Homo sapiens 16991 R-HSA-3134821 https://reactome.org/PathwayBrowser/#/R-HSA-3134821 DNA-PK binds microbial dsDNA TAS Homo sapiens 16991 R-HSA-3134822 https://reactome.org/PathwayBrowser/#/R-HSA-3134822 DDX41 binds viral dsDNA TAS Homo sapiens 16991 R-HSA-3134896 https://reactome.org/PathwayBrowser/#/R-HSA-3134896 LRR FLII-interacting protein 1 binds dsDNA TAS Homo sapiens 16991 R-HSA-3134901 https://reactome.org/PathwayBrowser/#/R-HSA-3134901 LRR FLII-interacting protein 1 associates with beta-catenin TAS Homo sapiens 16991 R-HSA-3134904 https://reactome.org/PathwayBrowser/#/R-HSA-3134904 Phosphorylation of beta-catenin at Ser552 TAS Homo sapiens 16991 R-HSA-3204303 https://reactome.org/PathwayBrowser/#/R-HSA-3204303 MRE11 binds cytosolic DNA TAS Homo sapiens 16991 R-HSA-3244605 https://reactome.org/PathwayBrowser/#/R-HSA-3244605 TREX1 binds retroviral-derived DNA TAS Homo sapiens 16991 R-HSA-3244614 https://reactome.org/PathwayBrowser/#/R-HSA-3244614 cGAS produces cyclic GMP-AMP TAS Homo sapiens 16991 R-HSA-3244647 https://reactome.org/PathwayBrowser/#/R-HSA-3244647 cGAS binds cytosolic DNA TAS Homo sapiens 16991 R-HSA-3245943 https://reactome.org/PathwayBrowser/#/R-HSA-3245943 Viral DNA cleavage by TREX1 TAS Homo sapiens 16991 R-HSA-3249386 https://reactome.org/PathwayBrowser/#/R-HSA-3249386 DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:dsDNA:ZBP1:TBK1 TAS Homo sapiens 16991 R-HSA-3785704 https://reactome.org/PathwayBrowser/#/R-HSA-3785704 DSB inducing agents induce double strand DNA breaks TAS Homo sapiens 16991 R-HSA-3785711 https://reactome.org/PathwayBrowser/#/R-HSA-3785711 Telomere shortening during replicative exhaustion TAS Homo sapiens 16991 R-HSA-427366 https://reactome.org/PathwayBrowser/#/R-HSA-427366 Transcription of intergenic spacer of the rRNA gene IEA Homo sapiens 16991 R-HSA-5220959 https://reactome.org/PathwayBrowser/#/R-HSA-5220959 TDG excises 5-formylcytosine TAS Homo sapiens 16991 R-HSA-5221061 https://reactome.org/PathwayBrowser/#/R-HSA-5221061 TDG excises 5-carboxylcytosine TAS Homo sapiens 16991 R-HSA-5601926 https://reactome.org/PathwayBrowser/#/R-HSA-5601926 RNA polymerase II polymerizes primary piRNA transcript IEA Homo sapiens 16991 R-HSA-5649655 https://reactome.org/PathwayBrowser/#/R-HSA-5649655 NEIL1 recognizes and binds DHU-dsDNA TAS Homo sapiens 16991 R-HSA-5649657 https://reactome.org/PathwayBrowser/#/R-HSA-5649657 NEIL1 recognizes and binds FapyG-dsDNA TAS Homo sapiens 16991 R-HSA-5649658 https://reactome.org/PathwayBrowser/#/R-HSA-5649658 NEIL1 cleaves DHU from damaged DNA TAS Homo sapiens 16991 R-HSA-5649664 https://reactome.org/PathwayBrowser/#/R-HSA-5649664 NEIL1 cleaves FapyG from damaged DNA TAS Homo sapiens 16991 R-HSA-5649671 https://reactome.org/PathwayBrowser/#/R-HSA-5649671 NEIL1 recognizes and binds FapyA-dsDNA TAS Homo sapiens 16991 R-HSA-5649673 https://reactome.org/PathwayBrowser/#/R-HSA-5649673 NEIL1 cleaves FapyA from damaged DNA TAS Homo sapiens 16991 R-HSA-5649681 https://reactome.org/PathwayBrowser/#/R-HSA-5649681 NEIL2 cleaves 5-OHU from damaged DNA TAS Homo sapiens 16991 R-HSA-5649686 https://reactome.org/PathwayBrowser/#/R-HSA-5649686 NEIL2 recognizes and binds 5-OHU-dsDNA TAS Homo sapiens 16991 R-HSA-5649701 https://reactome.org/PathwayBrowser/#/R-HSA-5649701 NEIL1,NEIL2 displace OGG1 from AP-dsDNA TAS Homo sapiens 16991 R-HSA-5649705 https://reactome.org/PathwayBrowser/#/R-HSA-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) TAS Homo sapiens 16991 R-HSA-5649708 https://reactome.org/PathwayBrowser/#/R-HSA-5649708 NEIL1,NEIL2 recruits POLB to incised AP site TAS Homo sapiens 16991 R-HSA-5649711 https://reactome.org/PathwayBrowser/#/R-HSA-5649711 NEIL1,NEIL2 incises DNA strand 5' to the AP site TAS Homo sapiens 16991 R-HSA-5649723 https://reactome.org/PathwayBrowser/#/R-HSA-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution TAS Homo sapiens 16991 R-HSA-5649724 https://reactome.org/PathwayBrowser/#/R-HSA-5649724 LIG3:XRCC1, POLB, NEIL1,NEIL2 and PNKP dissociate from the BER site TAS Homo sapiens 16991 R-HSA-5649725 https://reactome.org/PathwayBrowser/#/R-HSA-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) TAS Homo sapiens 16991 R-HSA-5649726 https://reactome.org/PathwayBrowser/#/R-HSA-5649726 LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA TAS Homo sapiens 16991 R-HSA-5649734 https://reactome.org/PathwayBrowser/#/R-HSA-5649734 LIG3 ligates NEIL1,NEIL2-generated single strand break TAS Homo sapiens 16991 R-HSA-5649854 https://reactome.org/PathwayBrowser/#/R-HSA-5649854 Recruitment of POLB to oxidatively damaged AP site TAS Homo sapiens 16991 R-HSA-5649856 https://reactome.org/PathwayBrowser/#/R-HSA-5649856 Oxidative damage to the AP site TAS Homo sapiens 16991 R-HSA-5649873 https://reactome.org/PathwayBrowser/#/R-HSA-5649873 PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site TAS Homo sapiens 16991 R-HSA-5649883 https://reactome.org/PathwayBrowser/#/R-HSA-5649883 POLB-mediated DNA strand displacement synthesis TAS Homo sapiens 16991 R-HSA-5651723 https://reactome.org/PathwayBrowser/#/R-HSA-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate TAS Homo sapiens 16991 R-HSA-5651739 https://reactome.org/PathwayBrowser/#/R-HSA-5651739 PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB TAS Homo sapiens 16991 R-HSA-5651773 https://reactome.org/PathwayBrowser/#/R-HSA-5651773 LIG1 binds POLB at long-patch BER site TAS Homo sapiens 16991 R-HSA-5651782 https://reactome.org/PathwayBrowser/#/R-HSA-5651782 FEN1 bound to POLB cleaves displaced DNA strand (flap) TAS Homo sapiens 16991 R-HSA-5651789 https://reactome.org/PathwayBrowser/#/R-HSA-5651789 LIG1 bound to POLB ligates SSB TAS Homo sapiens 16991 R-HSA-5651792 https://reactome.org/PathwayBrowser/#/R-HSA-5651792 LIG1 and POLB dissociate from repaired dsDNA TAS Homo sapiens 16991 R-HSA-5651805 https://reactome.org/PathwayBrowser/#/R-HSA-5651805 LIG1 bound to APEX1 and PCNA ligates SSB TAS Homo sapiens 16991 R-HSA-5651809 https://reactome.org/PathwayBrowser/#/R-HSA-5651809 LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA TAS Homo sapiens 16991 R-HSA-5651992 https://reactome.org/PathwayBrowser/#/R-HSA-5651992 PCNA-containing replication complex binds damaged dsDNA TAS Homo sapiens 16991 R-HSA-5652005 https://reactome.org/PathwayBrowser/#/R-HSA-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA TAS Homo sapiens 16991 R-HSA-5652009 https://reactome.org/PathwayBrowser/#/R-HSA-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA TAS Homo sapiens 16991 R-HSA-5652137 https://reactome.org/PathwayBrowser/#/R-HSA-5652137 Damaged dsDNA becomes damaged DNA template TAS Homo sapiens 16991 R-HSA-5652151 https://reactome.org/PathwayBrowser/#/R-HSA-5652151 REV1 recruits POLZ to (AP:Cyt)-DNA Template TAS Homo sapiens 16991 R-HSA-5653754 https://reactome.org/PathwayBrowser/#/R-HSA-5653754 UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA TAS Homo sapiens 16991 R-HSA-5653756 https://reactome.org/PathwayBrowser/#/R-HSA-5653756 TRIM25 binds monoUb:164-PCNA TAS Homo sapiens 16991 R-HSA-5653766 https://reactome.org/PathwayBrowser/#/R-HSA-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA TAS Homo sapiens 16991 R-HSA-5653770 https://reactome.org/PathwayBrowser/#/R-HSA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA TAS Homo sapiens 16991 R-HSA-5653780 https://reactome.org/PathwayBrowser/#/R-HSA-5653780 USP43 binds ISG:K164,ISG:K168-PCNA TAS Homo sapiens 16991 R-HSA-5653786 https://reactome.org/PathwayBrowser/#/R-HSA-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA TAS Homo sapiens 16991 R-HSA-5653838 https://reactome.org/PathwayBrowser/#/R-HSA-5653838 POLD,POLE binds deISGylated PCNA after TLS TAS Homo sapiens 16991 R-HSA-5653840 https://reactome.org/PathwayBrowser/#/R-HSA-5653840 POLD,POLE complete replication of damaged DNA after TLS TAS Homo sapiens 16991 R-HSA-5654985 https://reactome.org/PathwayBrowser/#/R-HSA-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH TAS Homo sapiens 16991 R-HSA-5654986 https://reactome.org/PathwayBrowser/#/R-HSA-5654986 SPRTN binds monoUb:K164-PCNA associated with POLH TAS Homo sapiens 16991 R-HSA-5654989 https://reactome.org/PathwayBrowser/#/R-HSA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA TAS Homo sapiens 16991 R-HSA-5655466 https://reactome.org/PathwayBrowser/#/R-HSA-5655466 USP1:WDR48 deubiquitinates monoUb:K164-PCNA TAS Homo sapiens 16991 R-HSA-5655481 https://reactome.org/PathwayBrowser/#/R-HSA-5655481 USP1:WDR48 binds monoUb:K164-PCNA TAS Homo sapiens 16991 R-HSA-5655835 https://reactome.org/PathwayBrowser/#/R-HSA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template TAS Homo sapiens 16991 R-HSA-5655892 https://reactome.org/PathwayBrowser/#/R-HSA-5655892 POLK incorporates dNMP opposite to damaged DNA base TAS Homo sapiens 16991 R-HSA-5655965 https://reactome.org/PathwayBrowser/#/R-HSA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini TAS Homo sapiens 16991 R-HSA-5656105 https://reactome.org/PathwayBrowser/#/R-HSA-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA TAS Homo sapiens 16991 R-HSA-5656148 https://reactome.org/PathwayBrowser/#/R-HSA-5656148 POLI incorporates dNMP opposite to damaged DNA base TAS Homo sapiens 16991 R-HSA-5656158 https://reactome.org/PathwayBrowser/#/R-HSA-5656158 POLZ elongates POLI-incorporated dNMP TAS Homo sapiens 16991 R-HSA-5657617 https://reactome.org/PathwayBrowser/#/R-HSA-5657617 ALKBH3 associated with ASCC1:ASCC2:ASCC3 binds alkylated dsDNA containing 3-meC TAS Homo sapiens 16991 R-HSA-5657637 https://reactome.org/PathwayBrowser/#/R-HSA-5657637 ALKBH3 associated with ASCC1:ASCC2:ASCC3 binds alkylated dsDNA containing 1-meA TAS Homo sapiens 16991 R-HSA-5657641 https://reactome.org/PathwayBrowser/#/R-HSA-5657641 ALKBH2 binds alkylated DNA containing 1-meA TAS Homo sapiens 16991 R-HSA-5657642 https://reactome.org/PathwayBrowser/#/R-HSA-5657642 ALKBH3 in complex with ASCC1:ASCC2:ASCC3 binds alkylated DNA containing 1-etA TAS Homo sapiens 16991 R-HSA-5657649 https://reactome.org/PathwayBrowser/#/R-HSA-5657649 ALKBH2 binds alkylated DNA containing 1-etA TAS Homo sapiens 16991 R-HSA-5657665 https://reactome.org/PathwayBrowser/#/R-HSA-5657665 ALKBH2 binds alkylated dsDNA containing 3-meC TAS Homo sapiens 16991 R-HSA-5686410 https://reactome.org/PathwayBrowser/#/R-HSA-5686410 BLM mediates dissolution of double Holliday junction TAS Homo sapiens 16991 R-HSA-5690997 https://reactome.org/PathwayBrowser/#/R-HSA-5690997 Ligation of newly synthesized repair patch to incised DNA in GG-NER TAS Homo sapiens 16991 R-HSA-5691001 https://reactome.org/PathwayBrowser/#/R-HSA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER TAS Homo sapiens 16991 R-HSA-5693558 https://reactome.org/PathwayBrowser/#/R-HSA-5693558 Gap-filling DNA synthesis in SDSA TAS Homo sapiens 16991 R-HSA-5693604 https://reactome.org/PathwayBrowser/#/R-HSA-5693604 XRCC4:LIG4 ligates DNA DSB ends during NHEJ TAS Homo sapiens 16991 R-HSA-6782234 https://reactome.org/PathwayBrowser/#/R-HSA-6782234 Recovery of RNA synthesis after TC-NER TAS Homo sapiens 16991 R-HSA-6785087 https://reactome.org/PathwayBrowser/#/R-HSA-6785087 FANCM:FAAP24 and APITD1:STRA13 bind ICL-DNA TAS Homo sapiens 16991 R-HSA-6785126 https://reactome.org/PathwayBrowser/#/R-HSA-6785126 FA core complex assembles at DNA interstrand crosslinks (ICLs) TAS Homo sapiens 16991 R-HSA-6785342 https://reactome.org/PathwayBrowser/#/R-HSA-6785342 FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex TAS Homo sapiens 16991 R-HSA-6785361 https://reactome.org/PathwayBrowser/#/R-HSA-6785361 Monoubiquitination of FANCD2:FANCI TAS Homo sapiens 16991 R-HSA-6785732 https://reactome.org/PathwayBrowser/#/R-HSA-6785732 DNA nucleases bind monoubiquitinated ID2 complex TAS Homo sapiens 16991 R-HSA-6785986 https://reactome.org/PathwayBrowser/#/R-HSA-6785986 DNA nucleases unhook the interstrand crosslink (ICL) TAS Homo sapiens 16991 R-HSA-6786155 https://reactome.org/PathwayBrowser/#/R-HSA-6786155 POLN binds ICL-DNA TAS Homo sapiens 16991 R-HSA-6786166 https://reactome.org/PathwayBrowser/#/R-HSA-6786166 Translesion synthesis across unhooked ICL by POLN TAS Homo sapiens 16991 R-HSA-6786171 https://reactome.org/PathwayBrowser/#/R-HSA-6786171 FANCD2 deubiquitination by USP1:WDR48 TAS Homo sapiens 16991 R-HSA-6788385 https://reactome.org/PathwayBrowser/#/R-HSA-6788385 The complex of ATR and ATRIP is recruited to ICL-DNA TAS Homo sapiens 16991 R-HSA-6788392 https://reactome.org/PathwayBrowser/#/R-HSA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA TAS Homo sapiens 16991 R-HSA-73892 https://reactome.org/PathwayBrowser/#/R-HSA-73892 MGMT/hAGT mediated DNA Damage Reversal TAS Homo sapiens 16991 R-HSA-73931 https://reactome.org/PathwayBrowser/#/R-HSA-73931 LIG3-mediated DNA ligation via the single-nucleotide replacement pathway TAS Homo sapiens 16991 R-HSA-73932 https://reactome.org/PathwayBrowser/#/R-HSA-73932 Resynthesis of excised residue by POLB TAS Homo sapiens 16991 R-HSA-844618 https://reactome.org/PathwayBrowser/#/R-HSA-844618 dsDNA:AIM2:ASC cluster binds procaspase-1 IEA Homo sapiens 16991 R-HSA-844619 https://reactome.org/PathwayBrowser/#/R-HSA-844619 AIM2 binds dsDNA TAS Homo sapiens 16991 R-HSA-844620 https://reactome.org/PathwayBrowser/#/R-HSA-844620 dsDNA:AIM2 clusters bind ASC IEA Homo sapiens 16991 R-HSA-874079 https://reactome.org/PathwayBrowser/#/R-HSA-874079 AIM2 oligomerizes IEA Homo sapiens 16991 R-HSA-8865711 https://reactome.org/PathwayBrowser/#/R-HSA-8865711 RAG1:RAG2 recombinase binds immunoglobulin kappa locus in a BRWD1-dependent manner IEA Homo sapiens 16991 R-HSA-8948703 https://reactome.org/PathwayBrowser/#/R-HSA-8948703 NLRP4 and DTX4 associate with p-S172-TBK1 within dsDNA:ZBP1:TBK1 TAS Homo sapiens 16991 R-HSA-8951690 https://reactome.org/PathwayBrowser/#/R-HSA-8951690 Formation of RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 TAS Homo sapiens 16991 R-HSA-8983671 https://reactome.org/PathwayBrowser/#/R-HSA-8983671 OAS1 binds viral dsRNA TAS Homo sapiens 16991 R-HSA-8983680 https://reactome.org/PathwayBrowser/#/R-HSA-8983680 OAS1 produces oligoadenylates TAS Homo sapiens 16991 R-HSA-8983688 https://reactome.org/PathwayBrowser/#/R-HSA-8983688 OAS1 oligomerizes TAS Homo sapiens 16991 R-HSA-8985091 https://reactome.org/PathwayBrowser/#/R-HSA-8985091 OAS3 produces oligoadenylates TAS Homo sapiens 16991 R-HSA-8985157 https://reactome.org/PathwayBrowser/#/R-HSA-8985157 OAS3 binds viral dsRNA TAS Homo sapiens 16991 R-HSA-9022453 https://reactome.org/PathwayBrowser/#/R-HSA-9022453 MECP2 binds 5hmC-DNA TAS Homo sapiens 16991 R-HSA-9022456 https://reactome.org/PathwayBrowser/#/R-HSA-9022456 MECP2 binds 5mC-DNA TAS Homo sapiens 16991 R-HSA-9022462 https://reactome.org/PathwayBrowser/#/R-HSA-9022462 MECP2 mutants R133C ,D121G, R133H and S134F do not bind 5hmC-DNA TAS Homo sapiens 16991 R-HSA-9022465 https://reactome.org/PathwayBrowser/#/R-HSA-9022465 MECP2 mutants R106W, D121G, R133H, S134F, T158M and T158A do not bind to 5mC-DNA TAS Homo sapiens 16991 R-HSA-912408 https://reactome.org/PathwayBrowser/#/R-HSA-912408 Telomeres cluster at the nuclear membrane IEA Homo sapiens 16991 R-HSA-913725 https://reactome.org/PathwayBrowser/#/R-HSA-913725 viral dsRNA binds IFIH1:TKFC TAS Homo sapiens 16991 R-HSA-918225 https://reactome.org/PathwayBrowser/#/R-HSA-918225 TBK1/IKK epsilon complex interacts with MAVS bound TRAF3 TAS Homo sapiens 16991 R-HSA-918227 https://reactome.org/PathwayBrowser/#/R-HSA-918227 Recruitment of TRAF3 to MAVS TAS Homo sapiens 16991 R-HSA-918229 https://reactome.org/PathwayBrowser/#/R-HSA-918229 Phosphorylation and release of IRF3/IRF7 TAS Homo sapiens 16991 R-HSA-918230 https://reactome.org/PathwayBrowser/#/R-HSA-918230 Recruitment of TRAF6/TRAF2 to IPS-1 TAS Homo sapiens 16991 R-HSA-918232 https://reactome.org/PathwayBrowser/#/R-HSA-918232 Recruitment of IRF3,IRF7 TAS Homo sapiens 16991 R-HSA-933523 https://reactome.org/PathwayBrowser/#/R-HSA-933523 Dimerzation of procaspase-8, procaspase-10 TAS Homo sapiens 16991 R-HSA-933525 https://reactome.org/PathwayBrowser/#/R-HSA-933525 Phosphorylation and release of IRF7 TAS Homo sapiens 16991 R-HSA-933526 https://reactome.org/PathwayBrowser/#/R-HSA-933526 Recruitment of caspase-8 and -10 to FADD complex TAS Homo sapiens 16991 R-HSA-933527 https://reactome.org/PathwayBrowser/#/R-HSA-933527 Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6 TAS Homo sapiens 16991 R-HSA-933528 https://reactome.org/PathwayBrowser/#/R-HSA-933528 Interaction of MEKK1 with TRAF6 IEA Homo sapiens 16991 R-HSA-933530 https://reactome.org/PathwayBrowser/#/R-HSA-933530 Activation of IKK by MEKK1 TAS Homo sapiens 16991 R-HSA-933532 https://reactome.org/PathwayBrowser/#/R-HSA-933532 Processing of caspases TAS Homo sapiens 16991 R-HSA-933537 https://reactome.org/PathwayBrowser/#/R-HSA-933537 Recruitment of TANK to TRAF6 TAS Homo sapiens 16991 R-HSA-933538 https://reactome.org/PathwayBrowser/#/R-HSA-933538 Recruitment of IRF7 to TRAF6 TAS Homo sapiens 16991 R-HSA-933539 https://reactome.org/PathwayBrowser/#/R-HSA-933539 Recruitment of IKK complex TAS Homo sapiens 16991 R-HSA-936378 https://reactome.org/PathwayBrowser/#/R-HSA-936378 Inhibition of DDX58/IFIH1 signaling by ATG5:ATG12:MAVS IEA Homo sapiens 16991 R-HSA-936381 https://reactome.org/PathwayBrowser/#/R-HSA-936381 OTUD5 deubiquitinates TRAF3 TAS Homo sapiens 16991 R-HSA-936475 https://reactome.org/PathwayBrowser/#/R-HSA-936475 Negative regulation of DDX58/IFIH1 signaling by RNF216 TAS Homo sapiens 16991 R-HSA-937343 https://reactome.org/PathwayBrowser/#/R-HSA-937343 NLRC5 interacts with DDX58/IFIH1 TAS Homo sapiens 16991 R-HSA-9605313 https://reactome.org/PathwayBrowser/#/R-HSA-9605313 Defective MUTYH mutants do not cleave adenine mispaired with 8-oxoguanine IEA Homo sapiens 16991 R-HSA-9608288 https://reactome.org/PathwayBrowser/#/R-HSA-9608288 Defective MUTYH mutants do not bind adenine mispaired with 8-oxoguanine TAS Homo sapiens 16991 R-HSA-9613490 https://reactome.org/PathwayBrowser/#/R-HSA-9613490 Unwinding of DNA for the nascent HIV-1 transcript: Second Transition IEA Homo sapiens 16991 R-HSA-9613498 https://reactome.org/PathwayBrowser/#/R-HSA-9613498 Unwinding of DNA for the nascent HIV-1 transcript IEA Homo sapiens 16991 R-HSA-9628737 https://reactome.org/PathwayBrowser/#/R-HSA-9628737 NEIL1 G83D does not cleave DHU TAS Homo sapiens 16991 R-HSA-9628756 https://reactome.org/PathwayBrowser/#/R-HSA-9628756 NEIL1 G83D does not cleave FapyA TAS Homo sapiens 16991 R-HSA-9628758 https://reactome.org/PathwayBrowser/#/R-HSA-9628758 NEIL1 G83D does not cleave FapyG TAS Homo sapiens 16991 R-HSA-9629149 https://reactome.org/PathwayBrowser/#/R-HSA-9629149 NEIL1 cleaves thymine glycol from damaged DNA TAS Homo sapiens 16991 R-HSA-9629154 https://reactome.org/PathwayBrowser/#/R-HSA-9629154 NEIL1 recognizes and binds thymine glycol TAS Homo sapiens 16991 R-HSA-9629166 https://reactome.org/PathwayBrowser/#/R-HSA-9629166 Defective NEIL1 variants do not cleave Tg TAS Homo sapiens 16991 R-HSA-9629195 https://reactome.org/PathwayBrowser/#/R-HSA-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA TAS Homo sapiens 16991 R-HSA-9629216 https://reactome.org/PathwayBrowser/#/R-HSA-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA TAS Homo sapiens 16991 R-HSA-9629245 https://reactome.org/PathwayBrowser/#/R-HSA-9629245 NEIL3 D132V does not cleave 5-guanidinohydantoin (Gh) TAS Homo sapiens 16991 R-HSA-9629358 https://reactome.org/PathwayBrowser/#/R-HSA-9629358 NEIL3 recognizes and binds to 5-guanidinohydantoin TAS Homo sapiens 16991 R-HSA-9629365 https://reactome.org/PathwayBrowser/#/R-HSA-9629365 NEIL3 recognizes and binds to spiroiminodihydantoin TAS Homo sapiens 16991 R-HSA-9629369 https://reactome.org/PathwayBrowser/#/R-HSA-9629369 NEIL3 recognizes and binds to thymine glycol IEA Homo sapiens 16991 R-HSA-9629372 https://reactome.org/PathwayBrowser/#/R-HSA-9629372 NEIL3 recognizes and binds to thymine glycol in telomeric DNA IEA Homo sapiens 16991 R-HSA-9629373 https://reactome.org/PathwayBrowser/#/R-HSA-9629373 NEIL3 recognizes and binds to spiroiminodihydantoin in telomeric DNA IEA Homo sapiens 16991 R-HSA-9629470 https://reactome.org/PathwayBrowser/#/R-HSA-9629470 NEIL3 cleaves 5-guanidinohydantoin TAS Homo sapiens 16991 R-HSA-9629483 https://reactome.org/PathwayBrowser/#/R-HSA-9629483 NEIL3 cleaves spiroiminodihydantoin from damaged telomeric DNA IEA Homo sapiens 16991 R-HSA-9629492 https://reactome.org/PathwayBrowser/#/R-HSA-9629492 NEIL3 cleaves spiroiminodihydantoin TAS Homo sapiens 16991 R-HSA-9629497 https://reactome.org/PathwayBrowser/#/R-HSA-9629497 NEIL3 cleaves thymine glycol from telomeric DNA IEA Homo sapiens 16991 R-HSA-9629499 https://reactome.org/PathwayBrowser/#/R-HSA-9629499 NEIL3 cleaves thymine glycol IEA Homo sapiens 16991 R-HSA-9630043 https://reactome.org/PathwayBrowser/#/R-HSA-9630043 Defective NTHL1 truncation mutants do not bind thymine glycol (Tg) TAS Homo sapiens 16991 R-HSA-9630044 https://reactome.org/PathwayBrowser/#/R-HSA-9630044 Defective NTHL1 truncation mutants do not bind formamidopyrimidine (FapyA) TAS Homo sapiens 16991 R-HSA-9630045 https://reactome.org/PathwayBrowser/#/R-HSA-9630045 Defective NTHL1 truncation mutants do not bind dihydrouracil (DHU) TAS Homo sapiens 16991 R-HSA-9630047 https://reactome.org/PathwayBrowser/#/R-HSA-9630047 Defective NTHL1 truncation mutants do not bind cytosine glycol (Cg) TAS Homo sapiens 16991 R-HSA-9630053 https://reactome.org/PathwayBrowser/#/R-HSA-9630053 NTHL1 D239Y does not cleave thymine glycol (Tg) TAS Homo sapiens 16991 R-HSA-9630055 https://reactome.org/PathwayBrowser/#/R-HSA-9630055 NTHL1 D239Y does not cleave dihydrouracil (DHU) TAS Homo sapiens 16991 R-HSA-9635996 https://reactome.org/PathwayBrowser/#/R-HSA-9635996 NEIL3 resolves psoralen-induced ICLs TAS Homo sapiens 16991 R-HSA-9636008 https://reactome.org/PathwayBrowser/#/R-HSA-9636008 NEIL3 resolves abasic site-induced ICLs IEA Homo sapiens 16991 R-HSA-9656250 https://reactome.org/PathwayBrowser/#/R-HSA-9656250 Defective OGG1 mutants do not excise 8-oxoguanine TAS Homo sapiens 16991 R-HSA-9656252 https://reactome.org/PathwayBrowser/#/R-HSA-9656252 Defective OGG1 mutants do not excise FapyG TAS Homo sapiens 16991 R-HSA-9656254 https://reactome.org/PathwayBrowser/#/R-HSA-9656254 Defective OGG1 mutants show decreased binding to 8-oxoguanine TAS Homo sapiens 16991 R-HSA-9670101 https://reactome.org/PathwayBrowser/#/R-HSA-9670101 ATRX:DAXX binds to subtelomeric chromosomal regions TAS Homo sapiens 16991 R-HSA-9670114 https://reactome.org/PathwayBrowser/#/R-HSA-9670114 Histone H3.3 deposition at telomere TAS Homo sapiens 16991 R-HSA-9670149 https://reactome.org/PathwayBrowser/#/R-HSA-9670149 TERRA transcription TAS Homo sapiens 16991 R-HSA-9679819 https://reactome.org/PathwayBrowser/#/R-HSA-9679819 TBK1 binds amlexanox TAS Homo sapiens 16991 R-HSA-9705137 https://reactome.org/PathwayBrowser/#/R-HSA-9705137 TBK1 or IKBKE forms homodimers TAS Homo sapiens 16991 R-HSA-9705145 https://reactome.org/PathwayBrowser/#/R-HSA-9705145 TBK1, IKBKE form homodimers TAS Homo sapiens 16991 R-HSA-9705320 https://reactome.org/PathwayBrowser/#/R-HSA-9705320 TBK1, IKBKE are autophosphorylated at Ser172 TAS Homo sapiens 16991 R-HSA-9705323 https://reactome.org/PathwayBrowser/#/R-HSA-9705323 Phosphorylation of TBK1/IKBKE TAS Homo sapiens 16991 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 16991 R-HSA-9713837 https://reactome.org/PathwayBrowser/#/R-HSA-9713837 Psoralens in combination with UV generate DNA interstrand crosslinks TAS Homo sapiens 16991 R-HSA-9730736 https://reactome.org/PathwayBrowser/#/R-HSA-9730736 Monofunctional chemotherapeutic alkylating drugs produce 3-methyladenine in dsDNA IEA Homo sapiens 16991 R-HSA-9730767 https://reactome.org/PathwayBrowser/#/R-HSA-9730767 Monofunctional chemotherapeutic alkylating drugs produce 7-methylguanine in dsDNA IEA Homo sapiens 16991 R-HSA-9732692 https://reactome.org/PathwayBrowser/#/R-HSA-9732692 Triazenes produce DNA damage in the form of O6-methylguanine IEA Homo sapiens 16991 R-HSA-977224 https://reactome.org/PathwayBrowser/#/R-HSA-977224 Serum amyloid P binds DNA and chromatin TAS Homo sapiens 16991 R-HSA-9817512 https://reactome.org/PathwayBrowser/#/R-HSA-9817512 UNG (UNG2) and base excision repair remove uridine and 5-methylcytidine from chromatin containing histone H3.3 IEA Homo sapiens 16991 R-HSA-9821967 https://reactome.org/PathwayBrowser/#/R-HSA-9821967 SRPK1 phosphorylates PRM2 in PRM2:dsDNA IEA Homo sapiens 16991 R-HSA-9821982 https://reactome.org/PathwayBrowser/#/R-HSA-9821982 SRPK1 phosphorylates PRM1 in PRM1:dsDNA IEA Homo sapiens 16991 R-HSA-9822115 https://reactome.org/PathwayBrowser/#/R-HSA-9822115 NPM2 dissociates p-S9-PRM1 from HIRA:NPM2:p-S9-PRM1:dsDNA IEA Homo sapiens 16991 R-HSA-9822117 https://reactome.org/PathwayBrowser/#/R-HSA-9822117 NPM2 and HIRA bind p-S9-PRM1:dsDNA IEA Homo sapiens 16991 R-HSA-9822185 https://reactome.org/PathwayBrowser/#/R-HSA-9822185 HIRA and NPM2 assemble H3.3-containing nucleosomes on paternal DNA IEA Homo sapiens 16991 R-HSA-990526 https://reactome.org/PathwayBrowser/#/R-HSA-990526 Recruitment of ITCH and K48 ubiquitination of MAVS TAS Homo sapiens 16991 R-HSA-990528 https://reactome.org/PathwayBrowser/#/R-HSA-990528 Interaction of PCBP2 with MAVS TAS Homo sapiens 16991 R-MMU-1810458 https://reactome.org/PathwayBrowser/#/R-MMU-1810458 Recruitment of Irf3 to activated Dai:Tbk1 TAS Mus musculus 16991 R-MMU-1810473 https://reactome.org/PathwayBrowser/#/R-MMU-1810473 Recruitment Tbk1 to dsDNA:Dai followed by its activation TAS Mus musculus 16991 R-MMU-3204303 https://reactome.org/PathwayBrowser/#/R-MMU-3204303 MRE11 binds cytosolic DNA IEA Mus musculus 16991 R-MMU-844619 https://reactome.org/PathwayBrowser/#/R-MMU-844619 AIM2 binds dsDNA IEA Mus musculus 16991 R-MMU-877385 https://reactome.org/PathwayBrowser/#/R-MMU-877385 dsDNA:Aim2 clusters bind Asc TAS Mus musculus 16991 R-MMU-877388 https://reactome.org/PathwayBrowser/#/R-MMU-877388 dsDNA:AIM2:ASC cluster binds procaspase-1 TAS Mus musculus 16991 R-MMU-877396 https://reactome.org/PathwayBrowser/#/R-MMU-877396 Aim2 oligomerizes TAS Mus musculus 16991 R-MMU-9750097 https://reactome.org/PathwayBrowser/#/R-MMU-9750097 ThioTEPA produces interstrand crosslinks in mouse DNA TAS Mus musculus 16991 R-MMU-9750281 https://reactome.org/PathwayBrowser/#/R-MMU-9750281 Uramustine produces interstrand crosslinks in mouse DNA TAS Mus musculus 16991 R-NUL-9606338 https://reactome.org/PathwayBrowser/#/R-NUL-9606338 Defective Mutyh mutants do not cleave adenine mispaired with 8-oxoguanine TAS Mus musculus 16991 R-NUL-9635966 https://reactome.org/PathwayBrowser/#/R-NUL-9635966 Mutyh cleaves adenine mispaired with 8-oxoguanine TAS Mus musculus 16991 R-PFA-3204303 https://reactome.org/PathwayBrowser/#/R-PFA-3204303 MRE11 binds cytosolic DNA IEA Plasmodium falciparum 16991 R-RNO-3204303 https://reactome.org/PathwayBrowser/#/R-RNO-3204303 MRE11 binds cytosolic DNA IEA Rattus norvegicus 16991 R-RNO-844619 https://reactome.org/PathwayBrowser/#/R-RNO-844619 AIM2 binds dsDNA IEA Rattus norvegicus 16991 R-SCE-3204303 https://reactome.org/PathwayBrowser/#/R-SCE-3204303 MRE11 binds cytosolic DNA IEA Saccharomyces cerevisiae 16991 R-SPO-3204303 https://reactome.org/PathwayBrowser/#/R-SPO-3204303 MRE11 binds cytosolic DNA IEA Schizosaccharomyces pombe 16991 R-SSC-3204303 https://reactome.org/PathwayBrowser/#/R-SSC-3204303 MRE11 binds cytosolic DNA IEA Sus scrofa 16991 R-XTR-3204303 https://reactome.org/PathwayBrowser/#/R-XTR-3204303 MRE11 binds cytosolic DNA IEA Xenopus tropicalis 16995 R-BTA-389862 https://reactome.org/PathwayBrowser/#/R-BTA-389862 Conversion of glyoxylate to oxalate IEA Bos taurus 16995 R-CEL-389862 https://reactome.org/PathwayBrowser/#/R-CEL-389862 Conversion of glyoxylate to oxalate IEA Caenorhabditis elegans 16995 R-CFA-389862 https://reactome.org/PathwayBrowser/#/R-CFA-389862 Conversion of glyoxylate to oxalate IEA Canis familiaris 16995 R-DDI-389862 https://reactome.org/PathwayBrowser/#/R-DDI-389862 Conversion of glyoxylate to oxalate IEA Dictyostelium discoideum 16995 R-DME-389862 https://reactome.org/PathwayBrowser/#/R-DME-389862 Conversion of glyoxylate to oxalate IEA Drosophila melanogaster 16995 R-DRE-389862 https://reactome.org/PathwayBrowser/#/R-DRE-389862 Conversion of glyoxylate to oxalate IEA Danio rerio 16995 R-GGA-389862 https://reactome.org/PathwayBrowser/#/R-GGA-389862 Conversion of glyoxylate to oxalate IEA Gallus gallus 16995 R-HSA-389862 https://reactome.org/PathwayBrowser/#/R-HSA-389862 Conversion of glyoxylate to oxalate TAS Homo sapiens 16995 R-MMU-389862 https://reactome.org/PathwayBrowser/#/R-MMU-389862 Conversion of glyoxylate to oxalate IEA Mus musculus 16995 R-RNO-389862 https://reactome.org/PathwayBrowser/#/R-RNO-389862 Conversion of glyoxylate to oxalate IEA Rattus norvegicus 16995 R-SSC-389862 https://reactome.org/PathwayBrowser/#/R-SSC-389862 Conversion of glyoxylate to oxalate IEA Sus scrofa 16995 R-XTR-389862 https://reactome.org/PathwayBrowser/#/R-XTR-389862 Conversion of glyoxylate to oxalate IEA Xenopus tropicalis 169974 R-BTA-9731590 https://reactome.org/PathwayBrowser/#/R-BTA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Bos taurus 169974 R-CFA-9731590 https://reactome.org/PathwayBrowser/#/R-CFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Canis familiaris 169974 R-DRE-9731590 https://reactome.org/PathwayBrowser/#/R-DRE-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Danio rerio 169974 R-GGA-9731590 https://reactome.org/PathwayBrowser/#/R-GGA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Gallus gallus 169974 R-HSA-9731590 https://reactome.org/PathwayBrowser/#/R-HSA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP TAS Homo sapiens 169974 R-MMU-9731590 https://reactome.org/PathwayBrowser/#/R-MMU-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Mus musculus 169974 R-PFA-9731590 https://reactome.org/PathwayBrowser/#/R-PFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Plasmodium falciparum 169974 R-RNO-9731590 https://reactome.org/PathwayBrowser/#/R-RNO-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Rattus norvegicus 169974 R-SSC-9731590 https://reactome.org/PathwayBrowser/#/R-SSC-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Sus scrofa 169974 R-XTR-9731590 https://reactome.org/PathwayBrowser/#/R-XTR-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Xenopus tropicalis 169975 R-BTA-9731590 https://reactome.org/PathwayBrowser/#/R-BTA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Bos taurus 169975 R-CFA-9731590 https://reactome.org/PathwayBrowser/#/R-CFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Canis familiaris 169975 R-DRE-9731590 https://reactome.org/PathwayBrowser/#/R-DRE-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Danio rerio 169975 R-GGA-9731590 https://reactome.org/PathwayBrowser/#/R-GGA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Gallus gallus 169975 R-HSA-9731590 https://reactome.org/PathwayBrowser/#/R-HSA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP TAS Homo sapiens 169975 R-MMU-9731590 https://reactome.org/PathwayBrowser/#/R-MMU-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Mus musculus 169975 R-PFA-9731590 https://reactome.org/PathwayBrowser/#/R-PFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Plasmodium falciparum 169975 R-RNO-9731590 https://reactome.org/PathwayBrowser/#/R-RNO-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Rattus norvegicus 169975 R-SSC-9731590 https://reactome.org/PathwayBrowser/#/R-SSC-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Sus scrofa 169975 R-XTR-9731590 https://reactome.org/PathwayBrowser/#/R-XTR-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Xenopus tropicalis 169976 R-BTA-9731613 https://reactome.org/PathwayBrowser/#/R-BTA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Bos taurus 169976 R-BTA-9731661 https://reactome.org/PathwayBrowser/#/R-BTA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Bos taurus 169976 R-CEL-9731661 https://reactome.org/PathwayBrowser/#/R-CEL-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Caenorhabditis elegans 169976 R-CFA-9731613 https://reactome.org/PathwayBrowser/#/R-CFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Canis familiaris 169976 R-CFA-9731661 https://reactome.org/PathwayBrowser/#/R-CFA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Canis familiaris 169976 R-DME-9731661 https://reactome.org/PathwayBrowser/#/R-DME-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Drosophila melanogaster 169976 R-DRE-9731613 https://reactome.org/PathwayBrowser/#/R-DRE-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Danio rerio 169976 R-DRE-9731661 https://reactome.org/PathwayBrowser/#/R-DRE-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Danio rerio 169976 R-GGA-9731613 https://reactome.org/PathwayBrowser/#/R-GGA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Gallus gallus 169976 R-GGA-9731661 https://reactome.org/PathwayBrowser/#/R-GGA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Gallus gallus 169976 R-HSA-9731613 https://reactome.org/PathwayBrowser/#/R-HSA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP TAS Homo sapiens 169976 R-HSA-9731661 https://reactome.org/PathwayBrowser/#/R-HSA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine TAS Homo sapiens 169976 R-MMU-9731613 https://reactome.org/PathwayBrowser/#/R-MMU-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Mus musculus 169976 R-MMU-9731661 https://reactome.org/PathwayBrowser/#/R-MMU-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Mus musculus 169976 R-PFA-9731613 https://reactome.org/PathwayBrowser/#/R-PFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Plasmodium falciparum 169976 R-RNO-9731613 https://reactome.org/PathwayBrowser/#/R-RNO-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Rattus norvegicus 169976 R-SSC-9731613 https://reactome.org/PathwayBrowser/#/R-SSC-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Sus scrofa 169976 R-SSC-9731661 https://reactome.org/PathwayBrowser/#/R-SSC-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Sus scrofa 169976 R-XTR-9731613 https://reactome.org/PathwayBrowser/#/R-XTR-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Xenopus tropicalis 169976 R-XTR-9731661 https://reactome.org/PathwayBrowser/#/R-XTR-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Xenopus tropicalis 17002 R-BTA-171059 https://reactome.org/PathwayBrowser/#/R-BTA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Bos taurus 17002 R-BTA-171106 https://reactome.org/PathwayBrowser/#/R-BTA-171106 LDLR:LDL complex => LDLR + LDL IEA Bos taurus 17002 R-BTA-171122 https://reactome.org/PathwayBrowser/#/R-BTA-171122 LDL + LDLR => LDL:LDLR complex IEA Bos taurus 17002 R-BTA-171141 https://reactome.org/PathwayBrowser/#/R-BTA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Bos taurus 17002 R-BTA-174587 https://reactome.org/PathwayBrowser/#/R-BTA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Bos taurus 17002 R-BTA-174657 https://reactome.org/PathwayBrowser/#/R-BTA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Bos taurus 17002 R-BTA-174660 https://reactome.org/PathwayBrowser/#/R-BTA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Bos taurus 17002 R-BTA-174690 https://reactome.org/PathwayBrowser/#/R-BTA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Bos taurus 17002 R-BTA-174706 https://reactome.org/PathwayBrowser/#/R-BTA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Bos taurus 17002 R-BTA-174739 https://reactome.org/PathwayBrowser/#/R-BTA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Bos taurus 17002 R-BTA-174741 https://reactome.org/PathwayBrowser/#/R-BTA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Bos taurus 17002 R-BTA-174757 https://reactome.org/PathwayBrowser/#/R-BTA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Bos taurus 17002 R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 17002 R-BTA-203130 https://reactome.org/PathwayBrowser/#/R-BTA-203130 OLR1 binds to oxidized LDL IEA Bos taurus 17002 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 17002 R-BTA-2187332 https://reactome.org/PathwayBrowser/#/R-BTA-2187332 Cytosolic CMs translocate to extracellular region IEA Bos taurus 17002 R-BTA-2197646 https://reactome.org/PathwayBrowser/#/R-BTA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Bos taurus 17002 R-BTA-2197770 https://reactome.org/PathwayBrowser/#/R-BTA-2197770 STAB1 (FEEL-1) binds ligands IEA Bos taurus 17002 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 17002 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 17002 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 17002 R-BTA-2247513 https://reactome.org/PathwayBrowser/#/R-BTA-2247513 STAB1:ligand is endocytosed IEA Bos taurus 17002 R-BTA-2395764 https://reactome.org/PathwayBrowser/#/R-BTA-2395764 atREs binds to nascent CM IEA Bos taurus 17002 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 17002 R-BTA-2395784 https://reactome.org/PathwayBrowser/#/R-BTA-2395784 Nascent CMs transform into mature CMs IEA Bos taurus 17002 R-BTA-2404131 https://reactome.org/PathwayBrowser/#/R-BTA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Bos taurus 17002 R-BTA-2423785 https://reactome.org/PathwayBrowser/#/R-BTA-2423785 CR:atREs binds apoE and HSPG IEA Bos taurus 17002 R-BTA-2512800 https://reactome.org/PathwayBrowser/#/R-BTA-2512800 SCARB1:ligand is endocytosed IEA Bos taurus 17002 R-BTA-264695 https://reactome.org/PathwayBrowser/#/R-BTA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Bos taurus 17002 R-BTA-266299 https://reactome.org/PathwayBrowser/#/R-BTA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Bos taurus 17002 R-BTA-266303 https://reactome.org/PathwayBrowser/#/R-BTA-266303 Spherical HDL binds C and E apolipoproteins IEA Bos taurus 17002 R-BTA-266310 https://reactome.org/PathwayBrowser/#/R-BTA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Bos taurus 17002 R-BTA-266315 https://reactome.org/PathwayBrowser/#/R-BTA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Bos taurus 17002 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 17002 R-BTA-349637 https://reactome.org/PathwayBrowser/#/R-BTA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Bos taurus 17002 R-BTA-349638 https://reactome.org/PathwayBrowser/#/R-BTA-349638 Disassembly of SR-BI-bound spherical HDL IEA Bos taurus 17002 R-BTA-349657 https://reactome.org/PathwayBrowser/#/R-BTA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Bos taurus 17002 R-BTA-432121 https://reactome.org/PathwayBrowser/#/R-BTA-432121 LDL binds to LRP8 IEA Bos taurus 17002 R-BTA-432129 https://reactome.org/PathwayBrowser/#/R-BTA-432129 FGR binds and phosphorylates LRP8 IEA Bos taurus 17002 R-BTA-435244 https://reactome.org/PathwayBrowser/#/R-BTA-435244 PECAM1 is phosphorylated IEA Bos taurus 17002 R-BTA-6813720 https://reactome.org/PathwayBrowser/#/R-BTA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Bos taurus 17002 R-BTA-8856630 https://reactome.org/PathwayBrowser/#/R-BTA-8856630 CIDEA:CIDEC binds lipid droplets IEA Bos taurus 17002 R-BTA-8858252 https://reactome.org/PathwayBrowser/#/R-BTA-8858252 HDLBP binds HDL IEA Bos taurus 17002 R-BTA-8862380 https://reactome.org/PathwayBrowser/#/R-BTA-8862380 HSD17B13 binds lipid droplets IEA Bos taurus 17002 R-BTA-8863471 https://reactome.org/PathwayBrowser/#/R-BTA-8863471 LDLR is bound by DAB2 and ARH IEA Bos taurus 17002 R-BTA-8865667 https://reactome.org/PathwayBrowser/#/R-BTA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Bos taurus 17002 R-BTA-8866304 https://reactome.org/PathwayBrowser/#/R-BTA-8866304 pre-VLDL binds lipids to form VLDL IEA Bos taurus 17002 R-BTA-8866327 https://reactome.org/PathwayBrowser/#/R-BTA-8866327 VLDL translocates from SER lumen to extracellular region IEA Bos taurus 17002 R-BTA-8867754 https://reactome.org/PathwayBrowser/#/R-BTA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Bos taurus 17002 R-BTA-8867756 https://reactome.org/PathwayBrowser/#/R-BTA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Bos taurus 17002 R-BTA-8868071 https://reactome.org/PathwayBrowser/#/R-BTA-8868071 Clathrin recruits PIK3C2A IEA Bos taurus 17002 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 17002 R-BTA-8868230 https://reactome.org/PathwayBrowser/#/R-BTA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Bos taurus 17002 R-BTA-8868236 https://reactome.org/PathwayBrowser/#/R-BTA-8868236 BAR domain proteins recruit dynamin IEA Bos taurus 17002 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 17002 R-BTA-8868651 https://reactome.org/PathwayBrowser/#/R-BTA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Bos taurus 17002 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 17002 R-BTA-8868659 https://reactome.org/PathwayBrowser/#/R-BTA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Bos taurus 17002 R-BTA-8868660 https://reactome.org/PathwayBrowser/#/R-BTA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Bos taurus 17002 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 17002 R-BTA-8869667 https://reactome.org/PathwayBrowser/#/R-BTA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Bos taurus 17002 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 17002 R-BTA-8871194 https://reactome.org/PathwayBrowser/#/R-BTA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Bos taurus 17002 R-BTA-8876366 https://reactome.org/PathwayBrowser/#/R-BTA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Bos taurus 17002 R-BTA-8876696 https://reactome.org/PathwayBrowser/#/R-BTA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Bos taurus 17002 R-BTA-8937442 https://reactome.org/PathwayBrowser/#/R-BTA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Bos taurus 17002 R-BTA-8948034 https://reactome.org/PathwayBrowser/#/R-BTA-8948034 FGR binds LDL:LRP8 IEA Bos taurus 17002 R-BTA-9707586 https://reactome.org/PathwayBrowser/#/R-BTA-9707586 FeHM oxidises LDL,HDL IEA Bos taurus 17002 R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 17002 R-CEL-264695 https://reactome.org/PathwayBrowser/#/R-CEL-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Caenorhabditis elegans 17002 R-CEL-6813720 https://reactome.org/PathwayBrowser/#/R-CEL-6813720 NCEH1 hydrolyzes cholesterol esters IEA Caenorhabditis elegans 17002 R-CEL-8876696 https://reactome.org/PathwayBrowser/#/R-CEL-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Caenorhabditis elegans 17002 R-CEL-8937442 https://reactome.org/PathwayBrowser/#/R-CEL-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Caenorhabditis elegans 17002 R-CFA-171059 https://reactome.org/PathwayBrowser/#/R-CFA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Canis familiaris 17002 R-CFA-171106 https://reactome.org/PathwayBrowser/#/R-CFA-171106 LDLR:LDL complex => LDLR + LDL IEA Canis familiaris 17002 R-CFA-171122 https://reactome.org/PathwayBrowser/#/R-CFA-171122 LDL + LDLR => LDL:LDLR complex IEA Canis familiaris 17002 R-CFA-171141 https://reactome.org/PathwayBrowser/#/R-CFA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Canis familiaris 17002 R-CFA-174587 https://reactome.org/PathwayBrowser/#/R-CFA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Canis familiaris 17002 R-CFA-174657 https://reactome.org/PathwayBrowser/#/R-CFA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Canis familiaris 17002 R-CFA-174660 https://reactome.org/PathwayBrowser/#/R-CFA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Canis familiaris 17002 R-CFA-174690 https://reactome.org/PathwayBrowser/#/R-CFA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Canis familiaris 17002 R-CFA-174706 https://reactome.org/PathwayBrowser/#/R-CFA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Canis familiaris 17002 R-CFA-174739 https://reactome.org/PathwayBrowser/#/R-CFA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Canis familiaris 17002 R-CFA-174741 https://reactome.org/PathwayBrowser/#/R-CFA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Canis familiaris 17002 R-CFA-174757 https://reactome.org/PathwayBrowser/#/R-CFA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Canis familiaris 17002 R-CFA-203130 https://reactome.org/PathwayBrowser/#/R-CFA-203130 OLR1 binds to oxidized LDL IEA Canis familiaris 17002 R-CFA-2187332 https://reactome.org/PathwayBrowser/#/R-CFA-2187332 Cytosolic CMs translocate to extracellular region IEA Canis familiaris 17002 R-CFA-2197646 https://reactome.org/PathwayBrowser/#/R-CFA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Canis familiaris 17002 R-CFA-2197770 https://reactome.org/PathwayBrowser/#/R-CFA-2197770 STAB1 (FEEL-1) binds ligands IEA Canis familiaris 17002 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 17002 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 17002 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 17002 R-CFA-2247513 https://reactome.org/PathwayBrowser/#/R-CFA-2247513 STAB1:ligand is endocytosed IEA Canis familiaris 17002 R-CFA-2395764 https://reactome.org/PathwayBrowser/#/R-CFA-2395764 atREs binds to nascent CM IEA Canis familiaris 17002 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 17002 R-CFA-2395784 https://reactome.org/PathwayBrowser/#/R-CFA-2395784 Nascent CMs transform into mature CMs IEA Canis familiaris 17002 R-CFA-2404131 https://reactome.org/PathwayBrowser/#/R-CFA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Canis familiaris 17002 R-CFA-2423785 https://reactome.org/PathwayBrowser/#/R-CFA-2423785 CR:atREs binds apoE and HSPG IEA Canis familiaris 17002 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 17002 R-CFA-2512800 https://reactome.org/PathwayBrowser/#/R-CFA-2512800 SCARB1:ligand is endocytosed IEA Canis familiaris 17002 R-CFA-266299 https://reactome.org/PathwayBrowser/#/R-CFA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Canis familiaris 17002 R-CFA-266303 https://reactome.org/PathwayBrowser/#/R-CFA-266303 Spherical HDL binds C and E apolipoproteins IEA Canis familiaris 17002 R-CFA-349637 https://reactome.org/PathwayBrowser/#/R-CFA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Canis familiaris 17002 R-CFA-349638 https://reactome.org/PathwayBrowser/#/R-CFA-349638 Disassembly of SR-BI-bound spherical HDL IEA Canis familiaris 17002 R-CFA-349657 https://reactome.org/PathwayBrowser/#/R-CFA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Canis familiaris 17002 R-CFA-432121 https://reactome.org/PathwayBrowser/#/R-CFA-432121 LDL binds to LRP8 IEA Canis familiaris 17002 R-CFA-432129 https://reactome.org/PathwayBrowser/#/R-CFA-432129 FGR binds and phosphorylates LRP8 IEA Canis familiaris 17002 R-CFA-435244 https://reactome.org/PathwayBrowser/#/R-CFA-435244 PECAM1 is phosphorylated IEA Canis familiaris 17002 R-CFA-6813720 https://reactome.org/PathwayBrowser/#/R-CFA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Canis familiaris 17002 R-CFA-8854408 https://reactome.org/PathwayBrowser/#/R-CFA-8854408 APOBR dimer binds VLDLs IEA Canis familiaris 17002 R-CFA-8854462 https://reactome.org/PathwayBrowser/#/R-CFA-8854462 VLDLR binds VLDL IEA Canis familiaris 17002 R-CFA-8856630 https://reactome.org/PathwayBrowser/#/R-CFA-8856630 CIDEA:CIDEC binds lipid droplets IEA Canis familiaris 17002 R-CFA-8858252 https://reactome.org/PathwayBrowser/#/R-CFA-8858252 HDLBP binds HDL IEA Canis familiaris 17002 R-CFA-8858270 https://reactome.org/PathwayBrowser/#/R-CFA-8858270 HILPDA binds lipid droplets IEA Canis familiaris 17002 R-CFA-8863471 https://reactome.org/PathwayBrowser/#/R-CFA-8863471 LDLR is bound by DAB2 and ARH IEA Canis familiaris 17002 R-CFA-8865667 https://reactome.org/PathwayBrowser/#/R-CFA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Canis familiaris 17002 R-CFA-8866304 https://reactome.org/PathwayBrowser/#/R-CFA-8866304 pre-VLDL binds lipids to form VLDL IEA Canis familiaris 17002 R-CFA-8866321 https://reactome.org/PathwayBrowser/#/R-CFA-8866321 VLDL binds APOC1 and APOC4 IEA Canis familiaris 17002 R-CFA-8866327 https://reactome.org/PathwayBrowser/#/R-CFA-8866327 VLDL translocates from SER lumen to extracellular region IEA Canis familiaris 17002 R-CFA-8867754 https://reactome.org/PathwayBrowser/#/R-CFA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Canis familiaris 17002 R-CFA-8867756 https://reactome.org/PathwayBrowser/#/R-CFA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Canis familiaris 17002 R-CFA-8868071 https://reactome.org/PathwayBrowser/#/R-CFA-8868071 Clathrin recruits PIK3C2A IEA Canis familiaris 17002 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 17002 R-CFA-8868230 https://reactome.org/PathwayBrowser/#/R-CFA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Canis familiaris 17002 R-CFA-8868236 https://reactome.org/PathwayBrowser/#/R-CFA-8868236 BAR domain proteins recruit dynamin IEA Canis familiaris 17002 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 17002 R-CFA-8868651 https://reactome.org/PathwayBrowser/#/R-CFA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Canis familiaris 17002 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 17002 R-CFA-8868659 https://reactome.org/PathwayBrowser/#/R-CFA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Canis familiaris 17002 R-CFA-8868660 https://reactome.org/PathwayBrowser/#/R-CFA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Canis familiaris 17002 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 17002 R-CFA-8871193 https://reactome.org/PathwayBrowser/#/R-CFA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Canis familiaris 17002 R-CFA-8871194 https://reactome.org/PathwayBrowser/#/R-CFA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Canis familiaris 17002 R-CFA-8876366 https://reactome.org/PathwayBrowser/#/R-CFA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Canis familiaris 17002 R-CFA-8876696 https://reactome.org/PathwayBrowser/#/R-CFA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Canis familiaris 17002 R-CFA-8948034 https://reactome.org/PathwayBrowser/#/R-CFA-8948034 FGR binds LDL:LRP8 IEA Canis familiaris 17002 R-CFA-9707586 https://reactome.org/PathwayBrowser/#/R-CFA-9707586 FeHM oxidises LDL,HDL IEA Canis familiaris 17002 R-DDI-6813720 https://reactome.org/PathwayBrowser/#/R-DDI-6813720 NCEH1 hydrolyzes cholesterol esters IEA Dictyostelium discoideum 17002 R-DDI-8937442 https://reactome.org/PathwayBrowser/#/R-DDI-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Dictyostelium discoideum 17002 R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 17002 R-DME-264695 https://reactome.org/PathwayBrowser/#/R-DME-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Drosophila melanogaster 17002 R-DME-8856630 https://reactome.org/PathwayBrowser/#/R-DME-8856630 CIDEA:CIDEC binds lipid droplets IEA Drosophila melanogaster 17002 R-DME-8862380 https://reactome.org/PathwayBrowser/#/R-DME-8862380 HSD17B13 binds lipid droplets IEA Drosophila melanogaster 17002 R-DME-8876696 https://reactome.org/PathwayBrowser/#/R-DME-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Drosophila melanogaster 17002 R-DME-8937442 https://reactome.org/PathwayBrowser/#/R-DME-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Drosophila melanogaster 17002 R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 17002 R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 17002 R-DRE-266299 https://reactome.org/PathwayBrowser/#/R-DRE-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Danio rerio 17002 R-DRE-349657 https://reactome.org/PathwayBrowser/#/R-DRE-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Danio rerio 17002 R-DRE-6813720 https://reactome.org/PathwayBrowser/#/R-DRE-6813720 NCEH1 hydrolyzes cholesterol esters IEA Danio rerio 17002 R-DRE-8876696 https://reactome.org/PathwayBrowser/#/R-DRE-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Danio rerio 17002 R-DRE-8937442 https://reactome.org/PathwayBrowser/#/R-DRE-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Danio rerio 17002 R-GGA-174587 https://reactome.org/PathwayBrowser/#/R-GGA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Gallus gallus 17002 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 17002 R-GGA-2187332 https://reactome.org/PathwayBrowser/#/R-GGA-2187332 Cytosolic CMs translocate to extracellular region IEA Gallus gallus 17002 R-GGA-2197646 https://reactome.org/PathwayBrowser/#/R-GGA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Gallus gallus 17002 R-GGA-2197770 https://reactome.org/PathwayBrowser/#/R-GGA-2197770 STAB1 (FEEL-1) binds ligands IEA Gallus gallus 17002 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 17002 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 17002 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 17002 R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus 17002 R-GGA-2395764 https://reactome.org/PathwayBrowser/#/R-GGA-2395764 atREs binds to nascent CM IEA Gallus gallus 17002 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 17002 R-GGA-2512800 https://reactome.org/PathwayBrowser/#/R-GGA-2512800 SCARB1:ligand is endocytosed IEA Gallus gallus 17002 R-GGA-264695 https://reactome.org/PathwayBrowser/#/R-GGA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Gallus gallus 17002 R-GGA-266299 https://reactome.org/PathwayBrowser/#/R-GGA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Gallus gallus 17002 R-GGA-266310 https://reactome.org/PathwayBrowser/#/R-GGA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Gallus gallus 17002 R-GGA-266315 https://reactome.org/PathwayBrowser/#/R-GGA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Gallus gallus 17002 R-GGA-266328 https://reactome.org/PathwayBrowser/#/R-GGA-266328 CETP-mediated lipid exchange: spherical HDL gains triacylglycerol IEA Gallus gallus 17002 R-GGA-266350 https://reactome.org/PathwayBrowser/#/R-GGA-266350 CETP-mediated lipid exchange: LDL gains cholesterol ester IEA Gallus gallus 17002 R-GGA-349404 https://reactome.org/PathwayBrowser/#/R-GGA-349404 CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex IEA Gallus gallus 17002 R-GGA-349637 https://reactome.org/PathwayBrowser/#/R-GGA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Gallus gallus 17002 R-GGA-349638 https://reactome.org/PathwayBrowser/#/R-GGA-349638 Disassembly of SR-BI-bound spherical HDL IEA Gallus gallus 17002 R-GGA-349657 https://reactome.org/PathwayBrowser/#/R-GGA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Gallus gallus 17002 R-GGA-432121 https://reactome.org/PathwayBrowser/#/R-GGA-432121 LDL binds to LRP8 IEA Gallus gallus 17002 R-GGA-432129 https://reactome.org/PathwayBrowser/#/R-GGA-432129 FGR binds and phosphorylates LRP8 IEA Gallus gallus 17002 R-GGA-435244 https://reactome.org/PathwayBrowser/#/R-GGA-435244 PECAM1 is phosphorylated IEA Gallus gallus 17002 R-GGA-6813720 https://reactome.org/PathwayBrowser/#/R-GGA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Gallus gallus 17002 R-GGA-8856630 https://reactome.org/PathwayBrowser/#/R-GGA-8856630 CIDEA:CIDEC binds lipid droplets IEA Gallus gallus 17002 R-GGA-8858252 https://reactome.org/PathwayBrowser/#/R-GGA-8858252 HDLBP binds HDL IEA Gallus gallus 17002 R-GGA-8862380 https://reactome.org/PathwayBrowser/#/R-GGA-8862380 HSD17B13 binds lipid droplets IEA Gallus gallus 17002 R-GGA-8865667 https://reactome.org/PathwayBrowser/#/R-GGA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Gallus gallus 17002 R-GGA-8866304 https://reactome.org/PathwayBrowser/#/R-GGA-8866304 pre-VLDL binds lipids to form VLDL IEA Gallus gallus 17002 R-GGA-8866327 https://reactome.org/PathwayBrowser/#/R-GGA-8866327 VLDL translocates from SER lumen to extracellular region IEA Gallus gallus 17002 R-GGA-8869667 https://reactome.org/PathwayBrowser/#/R-GGA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Gallus gallus 17002 R-GGA-8876366 https://reactome.org/PathwayBrowser/#/R-GGA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Gallus gallus 17002 R-GGA-8876696 https://reactome.org/PathwayBrowser/#/R-GGA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Gallus gallus 17002 R-GGA-8937442 https://reactome.org/PathwayBrowser/#/R-GGA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Gallus gallus 17002 R-GGA-8948034 https://reactome.org/PathwayBrowser/#/R-GGA-8948034 FGR binds LDL:LRP8 IEA Gallus gallus 17002 R-GGA-9707586 https://reactome.org/PathwayBrowser/#/R-GGA-9707586 FeHM oxidises LDL,HDL IEA Gallus gallus 17002 R-HSA-163432 https://reactome.org/PathwayBrowser/#/R-HSA-163432 cholesterol ester + H2O -> cholesterol + fatty acid IEA Homo sapiens 17002 R-HSA-171059 https://reactome.org/PathwayBrowser/#/R-HSA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] TAS Homo sapiens 17002 R-HSA-171106 https://reactome.org/PathwayBrowser/#/R-HSA-171106 LDLR:LDL complex => LDLR + LDL TAS Homo sapiens 17002 R-HSA-171122 https://reactome.org/PathwayBrowser/#/R-HSA-171122 LDL + LDLR => LDL:LDLR complex TAS Homo sapiens 17002 R-HSA-171141 https://reactome.org/PathwayBrowser/#/R-HSA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) TAS Homo sapiens 17002 R-HSA-174587 https://reactome.org/PathwayBrowser/#/R-HSA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] TAS Homo sapiens 17002 R-HSA-174624 https://reactome.org/PathwayBrowser/#/R-HSA-174624 chylomicron remnant:apoE:LDLR complex => chylomicron remnant:apoE + LDLR IEA Homo sapiens 17002 R-HSA-174657 https://reactome.org/PathwayBrowser/#/R-HSA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex TAS Homo sapiens 17002 R-HSA-174660 https://reactome.org/PathwayBrowser/#/R-HSA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron TAS Homo sapiens 17002 R-HSA-174690 https://reactome.org/PathwayBrowser/#/R-HSA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III TAS Homo sapiens 17002 R-HSA-174706 https://reactome.org/PathwayBrowser/#/R-HSA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) TAS Homo sapiens 17002 R-HSA-174739 https://reactome.org/PathwayBrowser/#/R-HSA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex TAS Homo sapiens 17002 R-HSA-174741 https://reactome.org/PathwayBrowser/#/R-HSA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron TAS Homo sapiens 17002 R-HSA-174757 https://reactome.org/PathwayBrowser/#/R-HSA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols TAS Homo sapiens 17002 R-HSA-174808 https://reactome.org/PathwayBrowser/#/R-HSA-174808 chylomicron remnant:apoE:LDLR complex [coated vesicle membrane] => chylomicron remnant:apoE:LDLR complex [endosome membrane] IEA Homo sapiens 17002 R-HSA-176879 https://reactome.org/PathwayBrowser/#/R-HSA-176879 apolipoprotein(a) + LDL => Lp(a) TAS Homo sapiens 17002 R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 17002 R-HSA-203130 https://reactome.org/PathwayBrowser/#/R-HSA-203130 OLR1 binds to oxidized LDL TAS Homo sapiens 17002 R-HSA-2168889 https://reactome.org/PathwayBrowser/#/R-HSA-2168889 Haptoglobin-related Protein binds Hemoglobin TAS Homo sapiens 17002 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 17002 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 17002 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 17002 R-HSA-2187332 https://reactome.org/PathwayBrowser/#/R-HSA-2187332 Cytosolic CMs translocate to extracellular region TAS Homo sapiens 17002 R-HSA-2197645 https://reactome.org/PathwayBrowser/#/R-HSA-2197645 SCARF1 (SREC-I) binds ligands IEA Homo sapiens 17002 R-HSA-2197646 https://reactome.org/PathwayBrowser/#/R-HSA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands TAS Homo sapiens 17002 R-HSA-2197770 https://reactome.org/PathwayBrowser/#/R-HSA-2197770 STAB1 (FEEL-1) binds ligands TAS Homo sapiens 17002 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 17002 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 17002 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 17002 R-HSA-2247513 https://reactome.org/PathwayBrowser/#/R-HSA-2247513 STAB1:ligand is endocytosed TAS Homo sapiens 17002 R-HSA-2247514 https://reactome.org/PathwayBrowser/#/R-HSA-2247514 SCARF1:ligand is endocytosed TAS Homo sapiens 17002 R-HSA-2395764 https://reactome.org/PathwayBrowser/#/R-HSA-2395764 atREs binds to nascent CM TAS Homo sapiens 17002 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 17002 R-HSA-2395784 https://reactome.org/PathwayBrowser/#/R-HSA-2395784 Nascent CMs transform into mature CMs TAS Homo sapiens 17002 R-HSA-2404131 https://reactome.org/PathwayBrowser/#/R-HSA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol TAS Homo sapiens 17002 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 17002 R-HSA-2423785 https://reactome.org/PathwayBrowser/#/R-HSA-2423785 CR:atREs binds apoE and HSPG TAS Homo sapiens 17002 R-HSA-2424254 https://reactome.org/PathwayBrowser/#/R-HSA-2424254 LDLR transports extracellular CR:atREs to cytosol IEA Homo sapiens 17002 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 17002 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 17002 R-HSA-2512800 https://reactome.org/PathwayBrowser/#/R-HSA-2512800 SCARB1:ligand is endocytosed TAS Homo sapiens 17002 R-HSA-264695 https://reactome.org/PathwayBrowser/#/R-HSA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) TAS Homo sapiens 17002 R-HSA-266299 https://reactome.org/PathwayBrowser/#/R-HSA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids TAS Homo sapiens 17002 R-HSA-266303 https://reactome.org/PathwayBrowser/#/R-HSA-266303 Spherical HDL binds C and E apolipoproteins TAS Homo sapiens 17002 R-HSA-266310 https://reactome.org/PathwayBrowser/#/R-HSA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL TAS Homo sapiens 17002 R-HSA-266315 https://reactome.org/PathwayBrowser/#/R-HSA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex TAS Homo sapiens 17002 R-HSA-266328 https://reactome.org/PathwayBrowser/#/R-HSA-266328 CETP-mediated lipid exchange: spherical HDL gains triacylglycerol TAS Homo sapiens 17002 R-HSA-266350 https://reactome.org/PathwayBrowser/#/R-HSA-266350 CETP-mediated lipid exchange: LDL gains cholesterol ester TAS Homo sapiens 17002 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 17002 R-HSA-349404 https://reactome.org/PathwayBrowser/#/R-HSA-349404 CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex TAS Homo sapiens 17002 R-HSA-349637 https://reactome.org/PathwayBrowser/#/R-HSA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface TAS Homo sapiens 17002 R-HSA-349638 https://reactome.org/PathwayBrowser/#/R-HSA-349638 Disassembly of SR-BI-bound spherical HDL TAS Homo sapiens 17002 R-HSA-349657 https://reactome.org/PathwayBrowser/#/R-HSA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle TAS Homo sapiens 17002 R-HSA-432121 https://reactome.org/PathwayBrowser/#/R-HSA-432121 LDL binds to LRP8 TAS Homo sapiens 17002 R-HSA-432129 https://reactome.org/PathwayBrowser/#/R-HSA-432129 FGR binds and phosphorylates LRP8 TAS Homo sapiens 17002 R-HSA-435244 https://reactome.org/PathwayBrowser/#/R-HSA-435244 PECAM1 is phosphorylated TAS Homo sapiens 17002 R-HSA-6813720 https://reactome.org/PathwayBrowser/#/R-HSA-6813720 NCEH1 hydrolyzes cholesterol esters TAS Homo sapiens 17002 R-HSA-8854408 https://reactome.org/PathwayBrowser/#/R-HSA-8854408 APOBR dimer binds VLDLs TAS Homo sapiens 17002 R-HSA-8854462 https://reactome.org/PathwayBrowser/#/R-HSA-8854462 VLDLR binds VLDL TAS Homo sapiens 17002 R-HSA-8856630 https://reactome.org/PathwayBrowser/#/R-HSA-8856630 CIDEA:CIDEC binds lipid droplets TAS Homo sapiens 17002 R-HSA-8858252 https://reactome.org/PathwayBrowser/#/R-HSA-8858252 HDLBP binds HDL TAS Homo sapiens 17002 R-HSA-8858270 https://reactome.org/PathwayBrowser/#/R-HSA-8858270 HILPDA binds lipid droplets TAS Homo sapiens 17002 R-HSA-8862380 https://reactome.org/PathwayBrowser/#/R-HSA-8862380 HSD17B13 binds lipid droplets TAS Homo sapiens 17002 R-HSA-8863471 https://reactome.org/PathwayBrowser/#/R-HSA-8863471 LDLR is bound by DAB2 and ARH TAS Homo sapiens 17002 R-HSA-8865667 https://reactome.org/PathwayBrowser/#/R-HSA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids TAS Homo sapiens 17002 R-HSA-8866304 https://reactome.org/PathwayBrowser/#/R-HSA-8866304 pre-VLDL binds lipids to form VLDL TAS Homo sapiens 17002 R-HSA-8866321 https://reactome.org/PathwayBrowser/#/R-HSA-8866321 VLDL binds APOC1 and APOC4 TAS Homo sapiens 17002 R-HSA-8866327 https://reactome.org/PathwayBrowser/#/R-HSA-8866327 VLDL translocates from SER lumen to extracellular region TAS Homo sapiens 17002 R-HSA-8867754 https://reactome.org/PathwayBrowser/#/R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit TAS Homo sapiens 17002 R-HSA-8867756 https://reactome.org/PathwayBrowser/#/R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit TAS Homo sapiens 17002 R-HSA-8868071 https://reactome.org/PathwayBrowser/#/R-HSA-8868071 Clathrin recruits PIK3C2A TAS Homo sapiens 17002 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 17002 R-HSA-8868230 https://reactome.org/PathwayBrowser/#/R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery TAS Homo sapiens 17002 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 17002 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 17002 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 17002 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 17002 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 17002 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 17002 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 17002 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 17002 R-HSA-8869667 https://reactome.org/PathwayBrowser/#/R-HSA-8869667 oxLDL:CD36 binds TLR4:TLR6 TAS Homo sapiens 17002 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 17002 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 17002 R-HSA-8876366 https://reactome.org/PathwayBrowser/#/R-HSA-8876366 LDL translocates from endosome lumen to lysosome lumen TAS Homo sapiens 17002 R-HSA-8876696 https://reactome.org/PathwayBrowser/#/R-HSA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST TAS Homo sapiens 17002 R-HSA-8876731 https://reactome.org/PathwayBrowser/#/R-HSA-8876731 CHEST translocates from ER membrane to lipid particle TAS Homo sapiens 17002 R-HSA-8933258 https://reactome.org/PathwayBrowser/#/R-HSA-8933258 LSR trimer binds LDL IEA Homo sapiens 17002 R-HSA-8933292 https://reactome.org/PathwayBrowser/#/R-HSA-8933292 LSR trimer binds VLDL IEA Homo sapiens 17002 R-HSA-8937442 https://reactome.org/PathwayBrowser/#/R-HSA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) TAS Homo sapiens 17002 R-HSA-8948034 https://reactome.org/PathwayBrowser/#/R-HSA-8948034 FGR binds LDL:LRP8 TAS Homo sapiens 17002 R-HSA-9707586 https://reactome.org/PathwayBrowser/#/R-HSA-9707586 FeHM oxidises LDL,HDL TAS Homo sapiens 17002 R-MMU-171059 https://reactome.org/PathwayBrowser/#/R-MMU-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Mus musculus 17002 R-MMU-171106 https://reactome.org/PathwayBrowser/#/R-MMU-171106 LDLR:LDL complex => LDLR + LDL IEA Mus musculus 17002 R-MMU-171122 https://reactome.org/PathwayBrowser/#/R-MMU-171122 LDL + LDLR => LDL:LDLR complex IEA Mus musculus 17002 R-MMU-171141 https://reactome.org/PathwayBrowser/#/R-MMU-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Mus musculus 17002 R-MMU-174587 https://reactome.org/PathwayBrowser/#/R-MMU-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Mus musculus 17002 R-MMU-174657 https://reactome.org/PathwayBrowser/#/R-MMU-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Mus musculus 17002 R-MMU-174660 https://reactome.org/PathwayBrowser/#/R-MMU-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Mus musculus 17002 R-MMU-174690 https://reactome.org/PathwayBrowser/#/R-MMU-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Mus musculus 17002 R-MMU-174706 https://reactome.org/PathwayBrowser/#/R-MMU-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Mus musculus 17002 R-MMU-174739 https://reactome.org/PathwayBrowser/#/R-MMU-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Mus musculus 17002 R-MMU-174741 https://reactome.org/PathwayBrowser/#/R-MMU-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Mus musculus 17002 R-MMU-174757 https://reactome.org/PathwayBrowser/#/R-MMU-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Mus musculus 17002 R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 17002 R-MMU-203130 https://reactome.org/PathwayBrowser/#/R-MMU-203130 OLR1 binds to oxidized LDL IEA Mus musculus 17002 R-MMU-2168889 https://reactome.org/PathwayBrowser/#/R-MMU-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Mus musculus 17002 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 17002 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 17002 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 17002 R-MMU-2187332 https://reactome.org/PathwayBrowser/#/R-MMU-2187332 Cytosolic CMs translocate to extracellular region IEA Mus musculus 17002 R-MMU-2197646 https://reactome.org/PathwayBrowser/#/R-MMU-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Mus musculus 17002 R-MMU-2197770 https://reactome.org/PathwayBrowser/#/R-MMU-2197770 STAB1 (FEEL-1) binds ligands IEA Mus musculus 17002 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 17002 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 17002 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 17002 R-MMU-2247513 https://reactome.org/PathwayBrowser/#/R-MMU-2247513 STAB1:ligand is endocytosed IEA Mus musculus 17002 R-MMU-2395764 https://reactome.org/PathwayBrowser/#/R-MMU-2395764 atREs binds to nascent CM IEA Mus musculus 17002 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 17002 R-MMU-2395784 https://reactome.org/PathwayBrowser/#/R-MMU-2395784 Nascent CMs transform into mature CMs IEA Mus musculus 17002 R-MMU-2404131 https://reactome.org/PathwayBrowser/#/R-MMU-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Mus musculus 17002 R-MMU-2423785 https://reactome.org/PathwayBrowser/#/R-MMU-2423785 CR:atREs binds apoE and HSPG IEA Mus musculus 17002 R-MMU-2425403 https://reactome.org/PathwayBrowser/#/R-MMU-2425403 Extracellular CR:atREs are transported to cytosol by Ldlr TAS Mus musculus 17002 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 17002 R-MMU-2512800 https://reactome.org/PathwayBrowser/#/R-MMU-2512800 SCARB1:ligand is endocytosed IEA Mus musculus 17002 R-MMU-264695 https://reactome.org/PathwayBrowser/#/R-MMU-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Mus musculus 17002 R-MMU-266299 https://reactome.org/PathwayBrowser/#/R-MMU-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Mus musculus 17002 R-MMU-266303 https://reactome.org/PathwayBrowser/#/R-MMU-266303 Spherical HDL binds C and E apolipoproteins IEA Mus musculus 17002 R-MMU-266310 https://reactome.org/PathwayBrowser/#/R-MMU-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Mus musculus 17002 R-MMU-266315 https://reactome.org/PathwayBrowser/#/R-MMU-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Mus musculus 17002 R-MMU-349637 https://reactome.org/PathwayBrowser/#/R-MMU-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Mus musculus 17002 R-MMU-349638 https://reactome.org/PathwayBrowser/#/R-MMU-349638 Disassembly of SR-BI-bound spherical HDL IEA Mus musculus 17002 R-MMU-349657 https://reactome.org/PathwayBrowser/#/R-MMU-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Mus musculus 17002 R-MMU-432121 https://reactome.org/PathwayBrowser/#/R-MMU-432121 LDL binds to LRP8 IEA Mus musculus 17002 R-MMU-432129 https://reactome.org/PathwayBrowser/#/R-MMU-432129 FGR binds and phosphorylates LRP8 IEA Mus musculus 17002 R-MMU-435244 https://reactome.org/PathwayBrowser/#/R-MMU-435244 PECAM1 is phosphorylated IEA Mus musculus 17002 R-MMU-6813720 https://reactome.org/PathwayBrowser/#/R-MMU-6813720 NCEH1 hydrolyzes cholesterol esters IEA Mus musculus 17002 R-MMU-8854408 https://reactome.org/PathwayBrowser/#/R-MMU-8854408 APOBR dimer binds VLDLs IEA Mus musculus 17002 R-MMU-8854462 https://reactome.org/PathwayBrowser/#/R-MMU-8854462 VLDLR binds VLDL IEA Mus musculus 17002 R-MMU-8856630 https://reactome.org/PathwayBrowser/#/R-MMU-8856630 CIDEA:CIDEC binds lipid droplets IEA Mus musculus 17002 R-MMU-8858252 https://reactome.org/PathwayBrowser/#/R-MMU-8858252 HDLBP binds HDL IEA Mus musculus 17002 R-MMU-8858270 https://reactome.org/PathwayBrowser/#/R-MMU-8858270 HILPDA binds lipid droplets IEA Mus musculus 17002 R-MMU-8862380 https://reactome.org/PathwayBrowser/#/R-MMU-8862380 HSD17B13 binds lipid droplets IEA Mus musculus 17002 R-MMU-8863471 https://reactome.org/PathwayBrowser/#/R-MMU-8863471 LDLR is bound by DAB2 and ARH IEA Mus musculus 17002 R-MMU-8865667 https://reactome.org/PathwayBrowser/#/R-MMU-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Mus musculus 17002 R-MMU-8866304 https://reactome.org/PathwayBrowser/#/R-MMU-8866304 pre-VLDL binds lipids to form VLDL IEA Mus musculus 17002 R-MMU-8866321 https://reactome.org/PathwayBrowser/#/R-MMU-8866321 VLDL binds APOC1 and APOC4 IEA Mus musculus 17002 R-MMU-8866327 https://reactome.org/PathwayBrowser/#/R-MMU-8866327 VLDL translocates from SER lumen to extracellular region IEA Mus musculus 17002 R-MMU-8867754 https://reactome.org/PathwayBrowser/#/R-MMU-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Mus musculus 17002 R-MMU-8867756 https://reactome.org/PathwayBrowser/#/R-MMU-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Mus musculus 17002 R-MMU-8868071 https://reactome.org/PathwayBrowser/#/R-MMU-8868071 Clathrin recruits PIK3C2A IEA Mus musculus 17002 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 17002 R-MMU-8868236 https://reactome.org/PathwayBrowser/#/R-MMU-8868236 BAR domain proteins recruit dynamin IEA Mus musculus 17002 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 17002 R-MMU-8868651 https://reactome.org/PathwayBrowser/#/R-MMU-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Mus musculus 17002 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 17002 R-MMU-8868659 https://reactome.org/PathwayBrowser/#/R-MMU-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Mus musculus 17002 R-MMU-8868660 https://reactome.org/PathwayBrowser/#/R-MMU-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Mus musculus 17002 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 17002 R-MMU-8869667 https://reactome.org/PathwayBrowser/#/R-MMU-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Mus musculus 17002 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 17002 R-MMU-8871194 https://reactome.org/PathwayBrowser/#/R-MMU-8871194 RAB5 and GAPVD1 bind AP-2 IEA Mus musculus 17002 R-MMU-8876366 https://reactome.org/PathwayBrowser/#/R-MMU-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Mus musculus 17002 R-MMU-8876696 https://reactome.org/PathwayBrowser/#/R-MMU-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Mus musculus 17002 R-MMU-8933256 https://reactome.org/PathwayBrowser/#/R-MMU-8933256 Lsr trimer binds LDL TAS Mus musculus 17002 R-MMU-8933295 https://reactome.org/PathwayBrowser/#/R-MMU-8933295 Lsr trimer binds VLDL TAS Mus musculus 17002 R-MMU-8937442 https://reactome.org/PathwayBrowser/#/R-MMU-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Mus musculus 17002 R-MMU-8948034 https://reactome.org/PathwayBrowser/#/R-MMU-8948034 FGR binds LDL:LRP8 IEA Mus musculus 17002 R-MMU-9707586 https://reactome.org/PathwayBrowser/#/R-MMU-9707586 FeHM oxidises LDL,HDL IEA Mus musculus 17002 R-RNO-163407 https://reactome.org/PathwayBrowser/#/R-RNO-163407 cholesterol ester + H2O -> cholesterol + fatty acid TAS Rattus norvegicus 17002 R-RNO-171059 https://reactome.org/PathwayBrowser/#/R-RNO-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Rattus norvegicus 17002 R-RNO-171106 https://reactome.org/PathwayBrowser/#/R-RNO-171106 LDLR:LDL complex => LDLR + LDL IEA Rattus norvegicus 17002 R-RNO-171122 https://reactome.org/PathwayBrowser/#/R-RNO-171122 LDL + LDLR => LDL:LDLR complex IEA Rattus norvegicus 17002 R-RNO-171141 https://reactome.org/PathwayBrowser/#/R-RNO-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Rattus norvegicus 17002 R-RNO-174587 https://reactome.org/PathwayBrowser/#/R-RNO-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Rattus norvegicus 17002 R-RNO-174657 https://reactome.org/PathwayBrowser/#/R-RNO-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Rattus norvegicus 17002 R-RNO-174660 https://reactome.org/PathwayBrowser/#/R-RNO-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Rattus norvegicus 17002 R-RNO-174690 https://reactome.org/PathwayBrowser/#/R-RNO-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Rattus norvegicus 17002 R-RNO-174706 https://reactome.org/PathwayBrowser/#/R-RNO-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Rattus norvegicus 17002 R-RNO-174739 https://reactome.org/PathwayBrowser/#/R-RNO-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Rattus norvegicus 17002 R-RNO-174741 https://reactome.org/PathwayBrowser/#/R-RNO-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Rattus norvegicus 17002 R-RNO-174757 https://reactome.org/PathwayBrowser/#/R-RNO-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Rattus norvegicus 17002 R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 17002 R-RNO-203130 https://reactome.org/PathwayBrowser/#/R-RNO-203130 OLR1 binds to oxidized LDL IEA Rattus norvegicus 17002 R-RNO-2168889 https://reactome.org/PathwayBrowser/#/R-RNO-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Rattus norvegicus 17002 R-RNO-2187332 https://reactome.org/PathwayBrowser/#/R-RNO-2187332 Cytosolic CMs translocate to extracellular region IEA Rattus norvegicus 17002 R-RNO-2197646 https://reactome.org/PathwayBrowser/#/R-RNO-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Rattus norvegicus 17002 R-RNO-2197770 https://reactome.org/PathwayBrowser/#/R-RNO-2197770 STAB1 (FEEL-1) binds ligands IEA Rattus norvegicus 17002 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 17002 R-RNO-2247513 https://reactome.org/PathwayBrowser/#/R-RNO-2247513 STAB1:ligand is endocytosed IEA Rattus norvegicus 17002 R-RNO-2395764 https://reactome.org/PathwayBrowser/#/R-RNO-2395764 atREs binds to nascent CM IEA Rattus norvegicus 17002 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 17002 R-RNO-2395784 https://reactome.org/PathwayBrowser/#/R-RNO-2395784 Nascent CMs transform into mature CMs IEA Rattus norvegicus 17002 R-RNO-2404131 https://reactome.org/PathwayBrowser/#/R-RNO-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Rattus norvegicus 17002 R-RNO-2423785 https://reactome.org/PathwayBrowser/#/R-RNO-2423785 CR:atREs binds apoE and HSPG IEA Rattus norvegicus 17002 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 17002 R-RNO-2512800 https://reactome.org/PathwayBrowser/#/R-RNO-2512800 SCARB1:ligand is endocytosed IEA Rattus norvegicus 17002 R-RNO-264695 https://reactome.org/PathwayBrowser/#/R-RNO-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Rattus norvegicus 17002 R-RNO-266299 https://reactome.org/PathwayBrowser/#/R-RNO-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Rattus norvegicus 17002 R-RNO-266303 https://reactome.org/PathwayBrowser/#/R-RNO-266303 Spherical HDL binds C and E apolipoproteins IEA Rattus norvegicus 17002 R-RNO-266310 https://reactome.org/PathwayBrowser/#/R-RNO-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Rattus norvegicus 17002 R-RNO-266315 https://reactome.org/PathwayBrowser/#/R-RNO-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Rattus norvegicus 17002 R-RNO-349637 https://reactome.org/PathwayBrowser/#/R-RNO-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Rattus norvegicus 17002 R-RNO-349638 https://reactome.org/PathwayBrowser/#/R-RNO-349638 Disassembly of SR-BI-bound spherical HDL IEA Rattus norvegicus 17002 R-RNO-349657 https://reactome.org/PathwayBrowser/#/R-RNO-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Rattus norvegicus 17002 R-RNO-432121 https://reactome.org/PathwayBrowser/#/R-RNO-432121 LDL binds to LRP8 IEA Rattus norvegicus 17002 R-RNO-432129 https://reactome.org/PathwayBrowser/#/R-RNO-432129 FGR binds and phosphorylates LRP8 IEA Rattus norvegicus 17002 R-RNO-435244 https://reactome.org/PathwayBrowser/#/R-RNO-435244 PECAM1 is phosphorylated IEA Rattus norvegicus 17002 R-RNO-6813720 https://reactome.org/PathwayBrowser/#/R-RNO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Rattus norvegicus 17002 R-RNO-8854408 https://reactome.org/PathwayBrowser/#/R-RNO-8854408 APOBR dimer binds VLDLs IEA Rattus norvegicus 17002 R-RNO-8854462 https://reactome.org/PathwayBrowser/#/R-RNO-8854462 VLDLR binds VLDL IEA Rattus norvegicus 17002 R-RNO-8856630 https://reactome.org/PathwayBrowser/#/R-RNO-8856630 CIDEA:CIDEC binds lipid droplets IEA Rattus norvegicus 17002 R-RNO-8858252 https://reactome.org/PathwayBrowser/#/R-RNO-8858252 HDLBP binds HDL IEA Rattus norvegicus 17002 R-RNO-8862380 https://reactome.org/PathwayBrowser/#/R-RNO-8862380 HSD17B13 binds lipid droplets IEA Rattus norvegicus 17002 R-RNO-8863471 https://reactome.org/PathwayBrowser/#/R-RNO-8863471 LDLR is bound by DAB2 and ARH IEA Rattus norvegicus 17002 R-RNO-8865667 https://reactome.org/PathwayBrowser/#/R-RNO-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Rattus norvegicus 17002 R-RNO-8866304 https://reactome.org/PathwayBrowser/#/R-RNO-8866304 pre-VLDL binds lipids to form VLDL IEA Rattus norvegicus 17002 R-RNO-8866321 https://reactome.org/PathwayBrowser/#/R-RNO-8866321 VLDL binds APOC1 and APOC4 IEA Rattus norvegicus 17002 R-RNO-8866327 https://reactome.org/PathwayBrowser/#/R-RNO-8866327 VLDL translocates from SER lumen to extracellular region IEA Rattus norvegicus 17002 R-RNO-8867754 https://reactome.org/PathwayBrowser/#/R-RNO-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Rattus norvegicus 17002 R-RNO-8867756 https://reactome.org/PathwayBrowser/#/R-RNO-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Rattus norvegicus 17002 R-RNO-8868071 https://reactome.org/PathwayBrowser/#/R-RNO-8868071 Clathrin recruits PIK3C2A IEA Rattus norvegicus 17002 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 17002 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus 17002 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 17002 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus 17002 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 17002 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus 17002 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus 17002 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 17002 R-RNO-8869667 https://reactome.org/PathwayBrowser/#/R-RNO-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Rattus norvegicus 17002 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 17002 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus 17002 R-RNO-8876366 https://reactome.org/PathwayBrowser/#/R-RNO-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Rattus norvegicus 17002 R-RNO-8876696 https://reactome.org/PathwayBrowser/#/R-RNO-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Rattus norvegicus 17002 R-RNO-8948034 https://reactome.org/PathwayBrowser/#/R-RNO-8948034 FGR binds LDL:LRP8 IEA Rattus norvegicus 17002 R-RNO-9707586 https://reactome.org/PathwayBrowser/#/R-RNO-9707586 FeHM oxidises LDL,HDL IEA Rattus norvegicus 17002 R-SCE-264695 https://reactome.org/PathwayBrowser/#/R-SCE-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Saccharomyces cerevisiae 17002 R-SCE-8862380 https://reactome.org/PathwayBrowser/#/R-SCE-8862380 HSD17B13 binds lipid droplets IEA Saccharomyces cerevisiae 17002 R-SPO-6813720 https://reactome.org/PathwayBrowser/#/R-SPO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Schizosaccharomyces pombe 17002 R-SSC-171059 https://reactome.org/PathwayBrowser/#/R-SSC-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Sus scrofa 17002 R-SSC-171106 https://reactome.org/PathwayBrowser/#/R-SSC-171106 LDLR:LDL complex => LDLR + LDL IEA Sus scrofa 17002 R-SSC-171122 https://reactome.org/PathwayBrowser/#/R-SSC-171122 LDL + LDLR => LDL:LDLR complex IEA Sus scrofa 17002 R-SSC-171141 https://reactome.org/PathwayBrowser/#/R-SSC-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Sus scrofa 17002 R-SSC-174587 https://reactome.org/PathwayBrowser/#/R-SSC-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Sus scrofa 17002 R-SSC-174657 https://reactome.org/PathwayBrowser/#/R-SSC-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Sus scrofa 17002 R-SSC-174660 https://reactome.org/PathwayBrowser/#/R-SSC-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Sus scrofa 17002 R-SSC-174690 https://reactome.org/PathwayBrowser/#/R-SSC-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Sus scrofa 17002 R-SSC-174706 https://reactome.org/PathwayBrowser/#/R-SSC-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Sus scrofa 17002 R-SSC-174739 https://reactome.org/PathwayBrowser/#/R-SSC-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Sus scrofa 17002 R-SSC-174741 https://reactome.org/PathwayBrowser/#/R-SSC-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Sus scrofa 17002 R-SSC-174757 https://reactome.org/PathwayBrowser/#/R-SSC-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Sus scrofa 17002 R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 17002 R-SSC-203130 https://reactome.org/PathwayBrowser/#/R-SSC-203130 OLR1 binds to oxidized LDL IEA Sus scrofa 17002 R-SSC-2168889 https://reactome.org/PathwayBrowser/#/R-SSC-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Sus scrofa 17002 R-SSC-2187332 https://reactome.org/PathwayBrowser/#/R-SSC-2187332 Cytosolic CMs translocate to extracellular region IEA Sus scrofa 17002 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa 17002 R-SSC-2197770 https://reactome.org/PathwayBrowser/#/R-SSC-2197770 STAB1 (FEEL-1) binds ligands IEA Sus scrofa 17002 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 17002 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 17002 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 17002 R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa 17002 R-SSC-2395764 https://reactome.org/PathwayBrowser/#/R-SSC-2395764 atREs binds to nascent CM IEA Sus scrofa 17002 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 17002 R-SSC-2395784 https://reactome.org/PathwayBrowser/#/R-SSC-2395784 Nascent CMs transform into mature CMs IEA Sus scrofa 17002 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa 17002 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa 17002 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 17002 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa 17002 R-SSC-264695 https://reactome.org/PathwayBrowser/#/R-SSC-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Sus scrofa 17002 R-SSC-266299 https://reactome.org/PathwayBrowser/#/R-SSC-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Sus scrofa 17002 R-SSC-266303 https://reactome.org/PathwayBrowser/#/R-SSC-266303 Spherical HDL binds C and E apolipoproteins IEA Sus scrofa 17002 R-SSC-266310 https://reactome.org/PathwayBrowser/#/R-SSC-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Sus scrofa 17002 R-SSC-266315 https://reactome.org/PathwayBrowser/#/R-SSC-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Sus scrofa 17002 R-SSC-349637 https://reactome.org/PathwayBrowser/#/R-SSC-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Sus scrofa 17002 R-SSC-349638 https://reactome.org/PathwayBrowser/#/R-SSC-349638 Disassembly of SR-BI-bound spherical HDL IEA Sus scrofa 17002 R-SSC-349657 https://reactome.org/PathwayBrowser/#/R-SSC-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Sus scrofa 17002 R-SSC-432121 https://reactome.org/PathwayBrowser/#/R-SSC-432121 LDL binds to LRP8 IEA Sus scrofa 17002 R-SSC-432129 https://reactome.org/PathwayBrowser/#/R-SSC-432129 FGR binds and phosphorylates LRP8 IEA Sus scrofa 17002 R-SSC-435244 https://reactome.org/PathwayBrowser/#/R-SSC-435244 PECAM1 is phosphorylated IEA Sus scrofa 17002 R-SSC-6813720 https://reactome.org/PathwayBrowser/#/R-SSC-6813720 NCEH1 hydrolyzes cholesterol esters IEA Sus scrofa 17002 R-SSC-8856630 https://reactome.org/PathwayBrowser/#/R-SSC-8856630 CIDEA:CIDEC binds lipid droplets IEA Sus scrofa 17002 R-SSC-8858252 https://reactome.org/PathwayBrowser/#/R-SSC-8858252 HDLBP binds HDL IEA Sus scrofa 17002 R-SSC-8858270 https://reactome.org/PathwayBrowser/#/R-SSC-8858270 HILPDA binds lipid droplets IEA Sus scrofa 17002 R-SSC-8862380 https://reactome.org/PathwayBrowser/#/R-SSC-8862380 HSD17B13 binds lipid droplets IEA Sus scrofa 17002 R-SSC-8863471 https://reactome.org/PathwayBrowser/#/R-SSC-8863471 LDLR is bound by DAB2 and ARH IEA Sus scrofa 17002 R-SSC-8865667 https://reactome.org/PathwayBrowser/#/R-SSC-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Sus scrofa 17002 R-SSC-8866304 https://reactome.org/PathwayBrowser/#/R-SSC-8866304 pre-VLDL binds lipids to form VLDL IEA Sus scrofa 17002 R-SSC-8866327 https://reactome.org/PathwayBrowser/#/R-SSC-8866327 VLDL translocates from SER lumen to extracellular region IEA Sus scrofa 17002 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa 17002 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa 17002 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa 17002 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 17002 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa 17002 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa 17002 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 17002 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa 17002 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 17002 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa 17002 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa 17002 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 17002 R-SSC-8869667 https://reactome.org/PathwayBrowser/#/R-SSC-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Sus scrofa 17002 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 17002 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa 17002 R-SSC-8876366 https://reactome.org/PathwayBrowser/#/R-SSC-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Sus scrofa 17002 R-SSC-8876696 https://reactome.org/PathwayBrowser/#/R-SSC-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Sus scrofa 17002 R-SSC-8937442 https://reactome.org/PathwayBrowser/#/R-SSC-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Sus scrofa 17002 R-SSC-8948034 https://reactome.org/PathwayBrowser/#/R-SSC-8948034 FGR binds LDL:LRP8 IEA Sus scrofa 17002 R-SSC-9707586 https://reactome.org/PathwayBrowser/#/R-SSC-9707586 FeHM oxidises LDL,HDL IEA Sus scrofa 17002 R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 17002 R-XTR-264695 https://reactome.org/PathwayBrowser/#/R-XTR-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Xenopus tropicalis 17002 R-XTR-8856630 https://reactome.org/PathwayBrowser/#/R-XTR-8856630 CIDEA:CIDEC binds lipid droplets IEA Xenopus tropicalis 17002 R-XTR-8862380 https://reactome.org/PathwayBrowser/#/R-XTR-8862380 HSD17B13 binds lipid droplets IEA Xenopus tropicalis 17002 R-XTR-8876696 https://reactome.org/PathwayBrowser/#/R-XTR-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Xenopus tropicalis 17009 R-BTA-6787533 https://reactome.org/PathwayBrowser/#/R-BTA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Bos taurus 17009 R-BTA-6787642 https://reactome.org/PathwayBrowser/#/R-BTA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Bos taurus 17009 R-BTA-742345 https://reactome.org/PathwayBrowser/#/R-BTA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Bos taurus 17009 R-CEL-6787533 https://reactome.org/PathwayBrowser/#/R-CEL-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Caenorhabditis elegans 17009 R-CEL-6787642 https://reactome.org/PathwayBrowser/#/R-CEL-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Caenorhabditis elegans 17009 R-CEL-742345 https://reactome.org/PathwayBrowser/#/R-CEL-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Caenorhabditis elegans 17009 R-CFA-6787533 https://reactome.org/PathwayBrowser/#/R-CFA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Canis familiaris 17009 R-CFA-6787642 https://reactome.org/PathwayBrowser/#/R-CFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Canis familiaris 17009 R-CFA-742345 https://reactome.org/PathwayBrowser/#/R-CFA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Canis familiaris 17009 R-DDI-6787533 https://reactome.org/PathwayBrowser/#/R-DDI-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Dictyostelium discoideum 17009 R-DDI-6787642 https://reactome.org/PathwayBrowser/#/R-DDI-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Dictyostelium discoideum 17009 R-DDI-742345 https://reactome.org/PathwayBrowser/#/R-DDI-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Dictyostelium discoideum 17009 R-DME-6787642 https://reactome.org/PathwayBrowser/#/R-DME-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Drosophila melanogaster 17009 R-DME-742345 https://reactome.org/PathwayBrowser/#/R-DME-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Drosophila melanogaster 17009 R-DRE-6787642 https://reactome.org/PathwayBrowser/#/R-DRE-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Danio rerio 17009 R-GGA-6787533 https://reactome.org/PathwayBrowser/#/R-GGA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Gallus gallus 17009 R-GGA-6787642 https://reactome.org/PathwayBrowser/#/R-GGA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Gallus gallus 17009 R-GGA-742345 https://reactome.org/PathwayBrowser/#/R-GGA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Gallus gallus 17009 R-HSA-1912349 https://reactome.org/PathwayBrowser/#/R-HSA-1912349 Fucosylation of Pre-NOTCH by POFUT1 IEA Homo sapiens 17009 R-HSA-5653596 https://reactome.org/PathwayBrowser/#/R-HSA-5653596 Defective SLC35C1 does not transport UDP-Fuc from cytosol to Golgi lumen TAS Homo sapiens 17009 R-HSA-6787533 https://reactome.org/PathwayBrowser/#/R-HSA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc TAS Homo sapiens 17009 R-HSA-6787642 https://reactome.org/PathwayBrowser/#/R-HSA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc TAS Homo sapiens 17009 R-HSA-742345 https://reactome.org/PathwayBrowser/#/R-HSA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen TAS Homo sapiens 17009 R-MMU-6787533 https://reactome.org/PathwayBrowser/#/R-MMU-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Mus musculus 17009 R-MMU-6787642 https://reactome.org/PathwayBrowser/#/R-MMU-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Mus musculus 17009 R-MMU-742345 https://reactome.org/PathwayBrowser/#/R-MMU-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Mus musculus 17009 R-NUL-1986584 https://reactome.org/PathwayBrowser/#/R-NUL-1986584 Fucosylation of Pre-Notch by POFUT1 TAS Cricetulus griseus 17009 R-PFA-6787642 https://reactome.org/PathwayBrowser/#/R-PFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Plasmodium falciparum 17009 R-PFA-742345 https://reactome.org/PathwayBrowser/#/R-PFA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Plasmodium falciparum 17009 R-RNO-6787533 https://reactome.org/PathwayBrowser/#/R-RNO-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Rattus norvegicus 17009 R-RNO-6787642 https://reactome.org/PathwayBrowser/#/R-RNO-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Rattus norvegicus 17009 R-RNO-742345 https://reactome.org/PathwayBrowser/#/R-RNO-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Rattus norvegicus 17009 R-SPO-742345 https://reactome.org/PathwayBrowser/#/R-SPO-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Schizosaccharomyces pombe 17009 R-SSC-6787533 https://reactome.org/PathwayBrowser/#/R-SSC-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Sus scrofa 17009 R-SSC-6787642 https://reactome.org/PathwayBrowser/#/R-SSC-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Sus scrofa 17009 R-SSC-742345 https://reactome.org/PathwayBrowser/#/R-SSC-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Sus scrofa 17009 R-XTR-6787533 https://reactome.org/PathwayBrowser/#/R-XTR-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Xenopus tropicalis 17009 R-XTR-6787642 https://reactome.org/PathwayBrowser/#/R-XTR-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Xenopus tropicalis 17009 R-XTR-742345 https://reactome.org/PathwayBrowser/#/R-XTR-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Xenopus tropicalis 17012 R-BTA-1022129 https://reactome.org/PathwayBrowser/#/R-BTA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Bos taurus 17012 R-BTA-1022133 https://reactome.org/PathwayBrowser/#/R-BTA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Bos taurus 17012 R-BTA-975902 https://reactome.org/PathwayBrowser/#/R-BTA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Bos taurus 17012 R-CFA-1022129 https://reactome.org/PathwayBrowser/#/R-CFA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Canis familiaris 17012 R-CFA-1022133 https://reactome.org/PathwayBrowser/#/R-CFA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Canis familiaris 17012 R-CFA-975902 https://reactome.org/PathwayBrowser/#/R-CFA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Canis familiaris 17012 R-DME-975902 https://reactome.org/PathwayBrowser/#/R-DME-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Drosophila melanogaster 17012 R-DRE-1022129 https://reactome.org/PathwayBrowser/#/R-DRE-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Danio rerio 17012 R-DRE-1022133 https://reactome.org/PathwayBrowser/#/R-DRE-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Danio rerio 17012 R-GGA-1022129 https://reactome.org/PathwayBrowser/#/R-GGA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Gallus gallus 17012 R-GGA-1022133 https://reactome.org/PathwayBrowser/#/R-GGA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Gallus gallus 17012 R-GGA-975902 https://reactome.org/PathwayBrowser/#/R-GGA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Gallus gallus 17012 R-HSA-1022129 https://reactome.org/PathwayBrowser/#/R-HSA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans TAS Homo sapiens 17012 R-HSA-1022133 https://reactome.org/PathwayBrowser/#/R-HSA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans TAS Homo sapiens 17012 R-HSA-975902 https://reactome.org/PathwayBrowser/#/R-HSA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans TAS Homo sapiens 17012 R-MMU-1022129 https://reactome.org/PathwayBrowser/#/R-MMU-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Mus musculus 17012 R-MMU-1022133 https://reactome.org/PathwayBrowser/#/R-MMU-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Mus musculus 17012 R-MMU-975902 https://reactome.org/PathwayBrowser/#/R-MMU-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Mus musculus 17012 R-RNO-1022129 https://reactome.org/PathwayBrowser/#/R-RNO-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Rattus norvegicus 17012 R-RNO-1022133 https://reactome.org/PathwayBrowser/#/R-RNO-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Rattus norvegicus 17012 R-RNO-975902 https://reactome.org/PathwayBrowser/#/R-RNO-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Rattus norvegicus 17012 R-SSC-1022129 https://reactome.org/PathwayBrowser/#/R-SSC-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Sus scrofa 17012 R-SSC-1022133 https://reactome.org/PathwayBrowser/#/R-SSC-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Sus scrofa 17012 R-SSC-975902 https://reactome.org/PathwayBrowser/#/R-SSC-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Sus scrofa 17012 R-XTR-1022129 https://reactome.org/PathwayBrowser/#/R-XTR-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Xenopus tropicalis 17012 R-XTR-1022133 https://reactome.org/PathwayBrowser/#/R-XTR-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Xenopus tropicalis 17012 R-XTR-975902 https://reactome.org/PathwayBrowser/#/R-XTR-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Xenopus tropicalis 17026 R-BTA-1449687 https://reactome.org/PathwayBrowser/#/R-BTA-1449687 Corticosteroids bind to CBG in blood IEA Bos taurus 17026 R-BTA-193052 https://reactome.org/PathwayBrowser/#/R-BTA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Bos taurus 17026 R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 17026 R-BTA-193964 https://reactome.org/PathwayBrowser/#/R-BTA-193964 CYP21A2 21-hydroxylates PROG IEA Bos taurus 17026 R-BTA-2534359 https://reactome.org/PathwayBrowser/#/R-BTA-2534359 CatSper Channel Mediated Calcium Transport IEA Bos taurus 17026 R-BTA-2534388 https://reactome.org/PathwayBrowser/#/R-BTA-2534388 Progesterone Activation Of CatSper IEA Bos taurus 17026 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 17026 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 17026 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 17026 R-BTA-9038161 https://reactome.org/PathwayBrowser/#/R-BTA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Bos taurus 17026 R-BTA-9038163 https://reactome.org/PathwayBrowser/#/R-BTA-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Bos taurus 17026 R-BTA-9725885 https://reactome.org/PathwayBrowser/#/R-BTA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Bos taurus 17026 R-CEL-1449687 https://reactome.org/PathwayBrowser/#/R-CEL-1449687 Corticosteroids bind to CBG in blood IEA Caenorhabditis elegans 17026 R-CFA-1449687 https://reactome.org/PathwayBrowser/#/R-CFA-1449687 Corticosteroids bind to CBG in blood IEA Canis familiaris 17026 R-CFA-193052 https://reactome.org/PathwayBrowser/#/R-CFA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Canis familiaris 17026 R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 17026 R-CFA-193964 https://reactome.org/PathwayBrowser/#/R-CFA-193964 CYP21A2 21-hydroxylates PROG IEA Canis familiaris 17026 R-CFA-2534359 https://reactome.org/PathwayBrowser/#/R-CFA-2534359 CatSper Channel Mediated Calcium Transport IEA Canis familiaris 17026 R-CFA-2534388 https://reactome.org/PathwayBrowser/#/R-CFA-2534388 Progesterone Activation Of CatSper IEA Canis familiaris 17026 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 17026 R-CFA-9725885 https://reactome.org/PathwayBrowser/#/R-CFA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Canis familiaris 17026 R-DDI-193964 https://reactome.org/PathwayBrowser/#/R-DDI-193964 CYP21A2 21-hydroxylates PROG IEA Dictyostelium discoideum 17026 R-DME-1449687 https://reactome.org/PathwayBrowser/#/R-DME-1449687 Corticosteroids bind to CBG in blood IEA Drosophila melanogaster 17026 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 17026 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 17026 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 17026 R-DME-9038161 https://reactome.org/PathwayBrowser/#/R-DME-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Drosophila melanogaster 17026 R-DME-9725885 https://reactome.org/PathwayBrowser/#/R-DME-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Drosophila melanogaster 17026 R-DRE-1449687 https://reactome.org/PathwayBrowser/#/R-DRE-1449687 Corticosteroids bind to CBG in blood IEA Danio rerio 17026 R-DRE-193052 https://reactome.org/PathwayBrowser/#/R-DRE-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Danio rerio 17026 R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 17026 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 17026 R-DRE-9038163 https://reactome.org/PathwayBrowser/#/R-DRE-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Danio rerio 17026 R-DRE-9725885 https://reactome.org/PathwayBrowser/#/R-DRE-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Danio rerio 17026 R-GGA-193052 https://reactome.org/PathwayBrowser/#/R-GGA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Gallus gallus 17026 R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 17026 R-GGA-193964 https://reactome.org/PathwayBrowser/#/R-GGA-193964 CYP21A2 21-hydroxylates PROG IEA Gallus gallus 17026 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 17026 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 17026 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 17026 R-GGA-9038161 https://reactome.org/PathwayBrowser/#/R-GGA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Gallus gallus 17026 R-GGA-9038163 https://reactome.org/PathwayBrowser/#/R-GGA-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Gallus gallus 17026 R-GGA-9725885 https://reactome.org/PathwayBrowser/#/R-GGA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Gallus gallus 17026 R-HSA-1449687 https://reactome.org/PathwayBrowser/#/R-HSA-1449687 Corticosteroids bind to CBG in blood TAS Homo sapiens 17026 R-HSA-193052 https://reactome.org/PathwayBrowser/#/R-HSA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone TAS Homo sapiens 17026 R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 17026 R-HSA-193964 https://reactome.org/PathwayBrowser/#/R-HSA-193964 CYP21A2 21-hydroxylates PROG TAS Homo sapiens 17026 R-HSA-2534359 https://reactome.org/PathwayBrowser/#/R-HSA-2534359 CatSper Channel Mediated Calcium Transport TAS Homo sapiens 17026 R-HSA-2534388 https://reactome.org/PathwayBrowser/#/R-HSA-2534388 Progesterone Activation Of CatSper TAS Homo sapiens 17026 R-HSA-5601976 https://reactome.org/PathwayBrowser/#/R-HSA-5601976 Defective CYP21A2 does not 21-hydroxylate PROG TAS Homo sapiens 17026 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 17026 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 17026 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 17026 R-HSA-9035954 https://reactome.org/PathwayBrowser/#/R-HSA-9035954 Defective CYP17A1 does not 17-hydroxylate P4 TAS Homo sapiens 17026 R-HSA-9038161 https://reactome.org/PathwayBrowser/#/R-HSA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG TAS Homo sapiens 17026 R-HSA-9038163 https://reactome.org/PathwayBrowser/#/R-HSA-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators TAS Homo sapiens 17026 R-HSA-9725885 https://reactome.org/PathwayBrowser/#/R-HSA-9725885 P4 bind PGR (in the HSP90 chaperone complex) TAS Homo sapiens 17026 R-MMU-1449687 https://reactome.org/PathwayBrowser/#/R-MMU-1449687 Corticosteroids bind to CBG in blood IEA Mus musculus 17026 R-MMU-193052 https://reactome.org/PathwayBrowser/#/R-MMU-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Mus musculus 17026 R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 17026 R-MMU-193964 https://reactome.org/PathwayBrowser/#/R-MMU-193964 CYP21A2 21-hydroxylates PROG IEA Mus musculus 17026 R-MMU-2534359 https://reactome.org/PathwayBrowser/#/R-MMU-2534359 CatSper Channel Mediated Calcium Transport IEA Mus musculus 17026 R-MMU-2534388 https://reactome.org/PathwayBrowser/#/R-MMU-2534388 Progesterone Activation Of CatSper IEA Mus musculus 17026 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 17026 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 17026 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 17026 R-MMU-9038161 https://reactome.org/PathwayBrowser/#/R-MMU-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Mus musculus 17026 R-MMU-9038163 https://reactome.org/PathwayBrowser/#/R-MMU-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Mus musculus 17026 R-MMU-9725885 https://reactome.org/PathwayBrowser/#/R-MMU-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Mus musculus 17026 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 17026 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 17026 R-PFA-9725885 https://reactome.org/PathwayBrowser/#/R-PFA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Plasmodium falciparum 17026 R-RNO-1449687 https://reactome.org/PathwayBrowser/#/R-RNO-1449687 Corticosteroids bind to CBG in blood IEA Rattus norvegicus 17026 R-RNO-193052 https://reactome.org/PathwayBrowser/#/R-RNO-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Rattus norvegicus 17026 R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 17026 R-RNO-193964 https://reactome.org/PathwayBrowser/#/R-RNO-193964 CYP21A2 21-hydroxylates PROG IEA Rattus norvegicus 17026 R-RNO-2534359 https://reactome.org/PathwayBrowser/#/R-RNO-2534359 CatSper Channel Mediated Calcium Transport IEA Rattus norvegicus 17026 R-RNO-2534388 https://reactome.org/PathwayBrowser/#/R-RNO-2534388 Progesterone Activation Of CatSper IEA Rattus norvegicus 17026 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 17026 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 17026 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 17026 R-RNO-9038161 https://reactome.org/PathwayBrowser/#/R-RNO-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Rattus norvegicus 17026 R-RNO-9038163 https://reactome.org/PathwayBrowser/#/R-RNO-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Rattus norvegicus 17026 R-RNO-9725885 https://reactome.org/PathwayBrowser/#/R-RNO-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Rattus norvegicus 17026 R-SSC-1449687 https://reactome.org/PathwayBrowser/#/R-SSC-1449687 Corticosteroids bind to CBG in blood IEA Sus scrofa 17026 R-SSC-193052 https://reactome.org/PathwayBrowser/#/R-SSC-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Sus scrofa 17026 R-SSC-193072 https://reactome.org/PathwayBrowser/#/R-SSC-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Sus scrofa 17026 R-SSC-193964 https://reactome.org/PathwayBrowser/#/R-SSC-193964 CYP21A2 21-hydroxylates PROG IEA Sus scrofa 17026 R-SSC-2534359 https://reactome.org/PathwayBrowser/#/R-SSC-2534359 CatSper Channel Mediated Calcium Transport IEA Sus scrofa 17026 R-SSC-2534388 https://reactome.org/PathwayBrowser/#/R-SSC-2534388 Progesterone Activation Of CatSper IEA Sus scrofa 17026 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 17026 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 17026 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 17026 R-SSC-9038161 https://reactome.org/PathwayBrowser/#/R-SSC-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Sus scrofa 17026 R-SSC-9038163 https://reactome.org/PathwayBrowser/#/R-SSC-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Sus scrofa 17026 R-SSC-9725885 https://reactome.org/PathwayBrowser/#/R-SSC-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Sus scrofa 17026 R-XTR-1449687 https://reactome.org/PathwayBrowser/#/R-XTR-1449687 Corticosteroids bind to CBG in blood IEA Xenopus tropicalis 17026 R-XTR-193072 https://reactome.org/PathwayBrowser/#/R-XTR-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Xenopus tropicalis 17029 R-BTA-6786421 https://reactome.org/PathwayBrowser/#/R-BTA-6786421 CHIA hydrolyses chitin IEA Bos taurus 17029 R-CFA-6786421 https://reactome.org/PathwayBrowser/#/R-CFA-6786421 CHIA hydrolyses chitin IEA Canis familiaris 17029 R-DME-6786421 https://reactome.org/PathwayBrowser/#/R-DME-6786421 CHIA hydrolyses chitin IEA Drosophila melanogaster 17029 R-GGA-6786421 https://reactome.org/PathwayBrowser/#/R-GGA-6786421 CHIA hydrolyses chitin IEA Gallus gallus 17029 R-HSA-6786421 https://reactome.org/PathwayBrowser/#/R-HSA-6786421 CHIA hydrolyses chitin TAS Homo sapiens 17029 R-MMU-6786421 https://reactome.org/PathwayBrowser/#/R-MMU-6786421 CHIA hydrolyses chitin IEA Mus musculus 17029 R-PFA-6786421 https://reactome.org/PathwayBrowser/#/R-PFA-6786421 CHIA hydrolyses chitin IEA Plasmodium falciparum 17029 R-RNO-6786421 https://reactome.org/PathwayBrowser/#/R-RNO-6786421 CHIA hydrolyses chitin IEA Rattus norvegicus 17029 R-SCE-6786421 https://reactome.org/PathwayBrowser/#/R-SCE-6786421 CHIA hydrolyses chitin IEA Saccharomyces cerevisiae 17029 R-SSC-6786421 https://reactome.org/PathwayBrowser/#/R-SSC-6786421 CHIA hydrolyses chitin IEA Sus scrofa 17044 R-CFA-170799 https://reactome.org/PathwayBrowser/#/R-CFA-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Canis familiaris 17044 R-CFA-170824 https://reactome.org/PathwayBrowser/#/R-CFA-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Canis familiaris 17044 R-HSA-170799 https://reactome.org/PathwayBrowser/#/R-HSA-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) TAS Homo sapiens 17044 R-HSA-170824 https://reactome.org/PathwayBrowser/#/R-HSA-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex TAS Homo sapiens 17044 R-MMU-170799 https://reactome.org/PathwayBrowser/#/R-MMU-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Mus musculus 17044 R-MMU-170824 https://reactome.org/PathwayBrowser/#/R-MMU-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Mus musculus 17044 R-RNO-170799 https://reactome.org/PathwayBrowser/#/R-RNO-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Rattus norvegicus 17044 R-RNO-170824 https://reactome.org/PathwayBrowser/#/R-RNO-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Rattus norvegicus 17044 R-XTR-170799 https://reactome.org/PathwayBrowser/#/R-XTR-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Xenopus tropicalis 17044 R-XTR-170824 https://reactome.org/PathwayBrowser/#/R-XTR-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Xenopus tropicalis 17051 R-HSA-432034 https://reactome.org/PathwayBrowser/#/R-HSA-432034 Aquaporin-6 passively transports anions into vesicles IEA Homo sapiens 17051 R-HSA-432036 https://reactome.org/PathwayBrowser/#/R-HSA-432036 Aquaporin-6 passively transports anions out of vesicles IEA Homo sapiens 17051 R-RNO-879862 https://reactome.org/PathwayBrowser/#/R-RNO-879862 Passive Transport of Anions into Vesicles by Aquaporin-6 (rat) TAS Rattus norvegicus 17051 R-RNO-879863 https://reactome.org/PathwayBrowser/#/R-RNO-879863 Passive Transport of Anions out of Vesicles by Aquaporin-6 (rat) TAS Rattus norvegicus 17052 R-MTU-964886 https://reactome.org/PathwayBrowser/#/R-MTU-964886 EPSP from shikimate 3-phosphate TAS Mycobacterium tuberculosis 17052 R-MTU-964939 https://reactome.org/PathwayBrowser/#/R-MTU-964939 Phosphorylation of shikimate TAS Mycobacterium tuberculosis 17066 R-BTA-73912 https://reactome.org/PathwayBrowser/#/R-BTA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Bos taurus 17066 R-BTA-73920 https://reactome.org/PathwayBrowser/#/R-BTA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Bos taurus 17066 R-CFA-73912 https://reactome.org/PathwayBrowser/#/R-CFA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Canis familiaris 17066 R-CFA-73920 https://reactome.org/PathwayBrowser/#/R-CFA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Canis familiaris 17066 R-DME-73912 https://reactome.org/PathwayBrowser/#/R-DME-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Drosophila melanogaster 17066 R-DME-73920 https://reactome.org/PathwayBrowser/#/R-DME-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Drosophila melanogaster 17066 R-DRE-73912 https://reactome.org/PathwayBrowser/#/R-DRE-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Danio rerio 17066 R-DRE-73920 https://reactome.org/PathwayBrowser/#/R-DRE-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Danio rerio 17066 R-GGA-73912 https://reactome.org/PathwayBrowser/#/R-GGA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Gallus gallus 17066 R-GGA-73920 https://reactome.org/PathwayBrowser/#/R-GGA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Gallus gallus 17066 R-HSA-73912 https://reactome.org/PathwayBrowser/#/R-HSA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ TAS Homo sapiens 17066 R-HSA-73920 https://reactome.org/PathwayBrowser/#/R-HSA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ TAS Homo sapiens 17066 R-MMU-73912 https://reactome.org/PathwayBrowser/#/R-MMU-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Mus musculus 17066 R-MMU-73920 https://reactome.org/PathwayBrowser/#/R-MMU-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Mus musculus 17066 R-RNO-73912 https://reactome.org/PathwayBrowser/#/R-RNO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Rattus norvegicus 17066 R-RNO-73920 https://reactome.org/PathwayBrowser/#/R-RNO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Rattus norvegicus 17066 R-SPO-73912 https://reactome.org/PathwayBrowser/#/R-SPO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Schizosaccharomyces pombe 17066 R-SPO-73920 https://reactome.org/PathwayBrowser/#/R-SPO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Schizosaccharomyces pombe 17066 R-SSC-73912 https://reactome.org/PathwayBrowser/#/R-SSC-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Sus scrofa 17066 R-SSC-73920 https://reactome.org/PathwayBrowser/#/R-SSC-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Sus scrofa 17066 R-XTR-73912 https://reactome.org/PathwayBrowser/#/R-XTR-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Xenopus tropicalis 17066 R-XTR-73920 https://reactome.org/PathwayBrowser/#/R-XTR-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Xenopus tropicalis 17103 R-BTA-9846501 https://reactome.org/PathwayBrowser/#/R-BTA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Bos taurus 17103 R-DME-9846501 https://reactome.org/PathwayBrowser/#/R-DME-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Drosophila melanogaster 17103 R-DRE-9846501 https://reactome.org/PathwayBrowser/#/R-DRE-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Danio rerio 17103 R-GGA-9846501 https://reactome.org/PathwayBrowser/#/R-GGA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Gallus gallus 17103 R-HSA-9846501 https://reactome.org/PathwayBrowser/#/R-HSA-9846501 B3GNT5 transfers GlcNAc to LacCer TAS Homo sapiens 17103 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 17103 R-MMU-9846501 https://reactome.org/PathwayBrowser/#/R-MMU-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Mus musculus 17103 R-RNO-9846501 https://reactome.org/PathwayBrowser/#/R-RNO-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Rattus norvegicus 17103 R-SSC-9846501 https://reactome.org/PathwayBrowser/#/R-SSC-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Sus scrofa 17103 R-XTR-9846501 https://reactome.org/PathwayBrowser/#/R-XTR-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Xenopus tropicalis 17105 R-BTA-71164 https://reactome.org/PathwayBrowser/#/R-BTA-71164 HGD dioxygenates homogentisate IEA Bos taurus 17105 R-BTA-71173 https://reactome.org/PathwayBrowser/#/R-BTA-71173 GSTZ1 isomerizes 4-MAA IEA Bos taurus 17105 R-CEL-71164 https://reactome.org/PathwayBrowser/#/R-CEL-71164 HGD dioxygenates homogentisate IEA Caenorhabditis elegans 17105 R-CEL-71173 https://reactome.org/PathwayBrowser/#/R-CEL-71173 GSTZ1 isomerizes 4-MAA IEA Caenorhabditis elegans 17105 R-CFA-71164 https://reactome.org/PathwayBrowser/#/R-CFA-71164 HGD dioxygenates homogentisate IEA Canis familiaris 17105 R-CFA-71173 https://reactome.org/PathwayBrowser/#/R-CFA-71173 GSTZ1 isomerizes 4-MAA IEA Canis familiaris 17105 R-DDI-71164 https://reactome.org/PathwayBrowser/#/R-DDI-71164 HGD dioxygenates homogentisate IEA Dictyostelium discoideum 17105 R-DDI-71173 https://reactome.org/PathwayBrowser/#/R-DDI-71173 GSTZ1 isomerizes 4-MAA IEA Dictyostelium discoideum 17105 R-DME-71164 https://reactome.org/PathwayBrowser/#/R-DME-71164 HGD dioxygenates homogentisate IEA Drosophila melanogaster 17105 R-DME-71173 https://reactome.org/PathwayBrowser/#/R-DME-71173 GSTZ1 isomerizes 4-MAA IEA Drosophila melanogaster 17105 R-DRE-71164 https://reactome.org/PathwayBrowser/#/R-DRE-71164 HGD dioxygenates homogentisate IEA Danio rerio 17105 R-DRE-71173 https://reactome.org/PathwayBrowser/#/R-DRE-71173 GSTZ1 isomerizes 4-MAA IEA Danio rerio 17105 R-GGA-71164 https://reactome.org/PathwayBrowser/#/R-GGA-71164 HGD dioxygenates homogentisate IEA Gallus gallus 17105 R-GGA-71173 https://reactome.org/PathwayBrowser/#/R-GGA-71173 GSTZ1 isomerizes 4-MAA IEA Gallus gallus 17105 R-HSA-71164 https://reactome.org/PathwayBrowser/#/R-HSA-71164 HGD dioxygenates homogentisate TAS Homo sapiens 17105 R-HSA-71173 https://reactome.org/PathwayBrowser/#/R-HSA-71173 GSTZ1 isomerizes 4-MAA TAS Homo sapiens 17105 R-MMU-71164 https://reactome.org/PathwayBrowser/#/R-MMU-71164 HGD dioxygenates homogentisate IEA Mus musculus 17105 R-MMU-71173 https://reactome.org/PathwayBrowser/#/R-MMU-71173 GSTZ1 isomerizes 4-MAA IEA Mus musculus 17105 R-RNO-71164 https://reactome.org/PathwayBrowser/#/R-RNO-71164 HGD dioxygenates homogentisate IEA Rattus norvegicus 17105 R-RNO-71173 https://reactome.org/PathwayBrowser/#/R-RNO-71173 GSTZ1 isomerizes 4-MAA IEA Rattus norvegicus 17105 R-SSC-71164 https://reactome.org/PathwayBrowser/#/R-SSC-71164 HGD dioxygenates homogentisate IEA Sus scrofa 17105 R-SSC-71173 https://reactome.org/PathwayBrowser/#/R-SSC-71173 GSTZ1 isomerizes 4-MAA IEA Sus scrofa 17105 R-XTR-71173 https://reactome.org/PathwayBrowser/#/R-XTR-71173 GSTZ1 isomerizes 4-MAA IEA Xenopus tropicalis 17118 R-BTA-189062 https://reactome.org/PathwayBrowser/#/R-BTA-189062 lactose + H2O => D-glucose + D-galactose IEA Bos taurus 17118 R-BTA-189242 https://reactome.org/PathwayBrowser/#/R-BTA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Bos taurus 17118 R-BTA-70355 https://reactome.org/PathwayBrowser/#/R-BTA-70355 GALK1 phosphorylates Gal to Gal1P IEA Bos taurus 17118 R-BTA-8932955 https://reactome.org/PathwayBrowser/#/R-BTA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Bos taurus 17118 R-CEL-189062 https://reactome.org/PathwayBrowser/#/R-CEL-189062 lactose + H2O => D-glucose + D-galactose IEA Caenorhabditis elegans 17118 R-CEL-189242 https://reactome.org/PathwayBrowser/#/R-CEL-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Caenorhabditis elegans 17118 R-CFA-189062 https://reactome.org/PathwayBrowser/#/R-CFA-189062 lactose + H2O => D-glucose + D-galactose IEA Canis familiaris 17118 R-CFA-189242 https://reactome.org/PathwayBrowser/#/R-CFA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Canis familiaris 17118 R-CFA-70355 https://reactome.org/PathwayBrowser/#/R-CFA-70355 GALK1 phosphorylates Gal to Gal1P IEA Canis familiaris 17118 R-CFA-8932955 https://reactome.org/PathwayBrowser/#/R-CFA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Canis familiaris 17118 R-DDI-189242 https://reactome.org/PathwayBrowser/#/R-DDI-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Dictyostelium discoideum 17118 R-DME-189062 https://reactome.org/PathwayBrowser/#/R-DME-189062 lactose + H2O => D-glucose + D-galactose IEA Drosophila melanogaster 17118 R-DME-189242 https://reactome.org/PathwayBrowser/#/R-DME-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Drosophila melanogaster 17118 R-DRE-189242 https://reactome.org/PathwayBrowser/#/R-DRE-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Danio rerio 17118 R-DRE-70355 https://reactome.org/PathwayBrowser/#/R-DRE-70355 GALK1 phosphorylates Gal to Gal1P IEA Danio rerio 17118 R-DRE-8932955 https://reactome.org/PathwayBrowser/#/R-DRE-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Danio rerio 17118 R-GGA-189062 https://reactome.org/PathwayBrowser/#/R-GGA-189062 lactose + H2O => D-glucose + D-galactose IEA Gallus gallus 17118 R-GGA-189242 https://reactome.org/PathwayBrowser/#/R-GGA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Gallus gallus 17118 R-GGA-70355 https://reactome.org/PathwayBrowser/#/R-GGA-70355 GALK1 phosphorylates Gal to Gal1P IEA Gallus gallus 17118 R-GGA-8932955 https://reactome.org/PathwayBrowser/#/R-GGA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Gallus gallus 17118 R-HSA-189062 https://reactome.org/PathwayBrowser/#/R-HSA-189062 lactose + H2O => D-glucose + D-galactose TAS Homo sapiens 17118 R-HSA-189242 https://reactome.org/PathwayBrowser/#/R-HSA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region TAS Homo sapiens 17118 R-HSA-5610026 https://reactome.org/PathwayBrowser/#/R-HSA-5610026 Defective GALK1 does not phosphorylate Gal TAS Homo sapiens 17118 R-HSA-5638222 https://reactome.org/PathwayBrowser/#/R-HSA-5638222 Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region TAS Homo sapiens 17118 R-HSA-70355 https://reactome.org/PathwayBrowser/#/R-HSA-70355 GALK1 phosphorylates Gal to Gal1P TAS Homo sapiens 17118 R-HSA-8932955 https://reactome.org/PathwayBrowser/#/R-HSA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol TAS Homo sapiens 17118 R-MMU-189062 https://reactome.org/PathwayBrowser/#/R-MMU-189062 lactose + H2O => D-glucose + D-galactose IEA Mus musculus 17118 R-MMU-189242 https://reactome.org/PathwayBrowser/#/R-MMU-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Mus musculus 17118 R-MMU-70355 https://reactome.org/PathwayBrowser/#/R-MMU-70355 GALK1 phosphorylates Gal to Gal1P IEA Mus musculus 17118 R-MMU-8932955 https://reactome.org/PathwayBrowser/#/R-MMU-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Mus musculus 17118 R-PFA-189242 https://reactome.org/PathwayBrowser/#/R-PFA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Plasmodium falciparum 17118 R-RNO-189062 https://reactome.org/PathwayBrowser/#/R-RNO-189062 lactose + H2O => D-glucose + D-galactose IEA Rattus norvegicus 17118 R-RNO-189242 https://reactome.org/PathwayBrowser/#/R-RNO-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Rattus norvegicus 17118 R-RNO-70355 https://reactome.org/PathwayBrowser/#/R-RNO-70355 GALK1 phosphorylates Gal to Gal1P IEA Rattus norvegicus 17118 R-RNO-8932955 https://reactome.org/PathwayBrowser/#/R-RNO-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Rattus norvegicus 17118 R-SCE-189242 https://reactome.org/PathwayBrowser/#/R-SCE-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Saccharomyces cerevisiae 17118 R-SSC-189062 https://reactome.org/PathwayBrowser/#/R-SSC-189062 lactose + H2O => D-glucose + D-galactose IEA Sus scrofa 17118 R-SSC-189242 https://reactome.org/PathwayBrowser/#/R-SSC-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Sus scrofa 17118 R-SSC-70355 https://reactome.org/PathwayBrowser/#/R-SSC-70355 GALK1 phosphorylates Gal to Gal1P IEA Sus scrofa 17118 R-SSC-8932955 https://reactome.org/PathwayBrowser/#/R-SSC-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Sus scrofa 17118 R-XTR-189062 https://reactome.org/PathwayBrowser/#/R-XTR-189062 lactose + H2O => D-glucose + D-galactose IEA Xenopus tropicalis 17118 R-XTR-189242 https://reactome.org/PathwayBrowser/#/R-XTR-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Xenopus tropicalis 17118 R-XTR-70355 https://reactome.org/PathwayBrowser/#/R-XTR-70355 GALK1 phosphorylates Gal to Gal1P IEA Xenopus tropicalis 17118 R-XTR-8932955 https://reactome.org/PathwayBrowser/#/R-XTR-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Xenopus tropicalis 17119 R-HSA-5389839 https://reactome.org/PathwayBrowser/#/R-HSA-5389839 39S subunit binds 28S subunit:mRNA:fMet-tRNA IEA Homo sapiens 17119 R-HSA-5389841 https://reactome.org/PathwayBrowser/#/R-HSA-5389841 MTFMT formylates methionyl-tRNA IEA Homo sapiens 17119 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 17119 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 17119 R-HSA-5389849 https://reactome.org/PathwayBrowser/#/R-HSA-5389849 28S subunit:MTIF3 binds MTIF2:GTP, mRNA, and formylMet-tRNA IEA Homo sapiens 17119 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 17119 R-HSA-5419261 https://reactome.org/PathwayBrowser/#/R-HSA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP TAS Homo sapiens 17119 R-HSA-5419279 https://reactome.org/PathwayBrowser/#/R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) IEA Homo sapiens 17120 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 17120 R-BTA-444171 https://reactome.org/PathwayBrowser/#/R-BTA-444171 Receptor FFAR2 binds carboxylates IEA Bos taurus 17120 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 17120 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 17120 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 17120 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 17120 R-CFA-444171 https://reactome.org/PathwayBrowser/#/R-CFA-444171 Receptor FFAR2 binds carboxylates IEA Canis familiaris 17120 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 17120 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 17120 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 17120 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 17120 R-DRE-444171 https://reactome.org/PathwayBrowser/#/R-DRE-444171 Receptor FFAR2 binds carboxylates IEA Danio rerio 17120 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 17120 R-GGA-444171 https://reactome.org/PathwayBrowser/#/R-GGA-444171 Receptor FFAR2 binds carboxylates IEA Gallus gallus 17120 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 17120 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 17120 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 17120 R-HSA-444171 https://reactome.org/PathwayBrowser/#/R-HSA-444171 Receptor FFAR2 binds carboxylates TAS Homo sapiens 17120 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 17120 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 17120 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 17120 R-MMU-444171 https://reactome.org/PathwayBrowser/#/R-MMU-444171 Receptor FFAR2 binds carboxylates IEA Mus musculus 17120 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 17120 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 17120 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 17120 R-RNO-444171 https://reactome.org/PathwayBrowser/#/R-RNO-444171 Receptor FFAR2 binds carboxylates IEA Rattus norvegicus 17120 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 17120 R-SSC-444171 https://reactome.org/PathwayBrowser/#/R-SSC-444171 Receptor FFAR2 binds carboxylates IEA Sus scrofa 17120 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 17120 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 17120 R-XTR-444171 https://reactome.org/PathwayBrowser/#/R-XTR-444171 Receptor FFAR2 binds carboxylates IEA Xenopus tropicalis 17120 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 17120 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 17122 R-BTA-4085021 https://reactome.org/PathwayBrowser/#/R-BTA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Bos taurus 17122 R-BTA-4085028 https://reactome.org/PathwayBrowser/#/R-BTA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Bos taurus 17122 R-BTA-4085217 https://reactome.org/PathwayBrowser/#/R-BTA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Bos taurus 17122 R-BTA-6803761 https://reactome.org/PathwayBrowser/#/R-BTA-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Bos taurus 17122 R-CFA-4085021 https://reactome.org/PathwayBrowser/#/R-CFA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Canis familiaris 17122 R-CFA-4085028 https://reactome.org/PathwayBrowser/#/R-CFA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Canis familiaris 17122 R-CFA-4085217 https://reactome.org/PathwayBrowser/#/R-CFA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Canis familiaris 17122 R-DRE-4085021 https://reactome.org/PathwayBrowser/#/R-DRE-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Danio rerio 17122 R-DRE-4085028 https://reactome.org/PathwayBrowser/#/R-DRE-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Danio rerio 17122 R-DRE-4085217 https://reactome.org/PathwayBrowser/#/R-DRE-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Danio rerio 17122 R-GGA-4085021 https://reactome.org/PathwayBrowser/#/R-GGA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Gallus gallus 17122 R-GGA-4085028 https://reactome.org/PathwayBrowser/#/R-GGA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Gallus gallus 17122 R-GGA-4085217 https://reactome.org/PathwayBrowser/#/R-GGA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Gallus gallus 17122 R-HSA-4085021 https://reactome.org/PathwayBrowser/#/R-HSA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP TAS Homo sapiens 17122 R-HSA-4085028 https://reactome.org/PathwayBrowser/#/R-HSA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P TAS Homo sapiens 17122 R-HSA-4085217 https://reactome.org/PathwayBrowser/#/R-HSA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate TAS Homo sapiens 17122 R-HSA-4088322 https://reactome.org/PathwayBrowser/#/R-HSA-4088322 Defective GNE does not phosphorylate ManNAc to ManNAc-6-P TAS Homo sapiens 17122 R-HSA-6803761 https://reactome.org/PathwayBrowser/#/R-HSA-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc TAS Homo sapiens 17122 R-MMU-4085021 https://reactome.org/PathwayBrowser/#/R-MMU-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Mus musculus 17122 R-MMU-4085028 https://reactome.org/PathwayBrowser/#/R-MMU-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Mus musculus 17122 R-MMU-4085217 https://reactome.org/PathwayBrowser/#/R-MMU-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Mus musculus 17122 R-MMU-6803761 https://reactome.org/PathwayBrowser/#/R-MMU-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Mus musculus 17122 R-RNO-4085021 https://reactome.org/PathwayBrowser/#/R-RNO-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Rattus norvegicus 17122 R-RNO-4085028 https://reactome.org/PathwayBrowser/#/R-RNO-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Rattus norvegicus 17122 R-RNO-4085217 https://reactome.org/PathwayBrowser/#/R-RNO-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Rattus norvegicus 17122 R-RNO-6803761 https://reactome.org/PathwayBrowser/#/R-RNO-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Rattus norvegicus 17122 R-SSC-4085021 https://reactome.org/PathwayBrowser/#/R-SSC-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Sus scrofa 17122 R-SSC-4085028 https://reactome.org/PathwayBrowser/#/R-SSC-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Sus scrofa 17122 R-SSC-4085217 https://reactome.org/PathwayBrowser/#/R-SSC-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Sus scrofa 17122 R-SSC-6803761 https://reactome.org/PathwayBrowser/#/R-SSC-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Sus scrofa 17122 R-XTR-4085021 https://reactome.org/PathwayBrowser/#/R-XTR-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Xenopus tropicalis 17122 R-XTR-4085028 https://reactome.org/PathwayBrowser/#/R-XTR-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Xenopus tropicalis 17122 R-XTR-4085217 https://reactome.org/PathwayBrowser/#/R-XTR-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Xenopus tropicalis 17122 R-XTR-6803761 https://reactome.org/PathwayBrowser/#/R-XTR-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Xenopus tropicalis 17126 R-BTA-165026 https://reactome.org/PathwayBrowser/#/R-BTA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Bos taurus 17126 R-BTA-200406 https://reactome.org/PathwayBrowser/#/R-BTA-200406 CPT1A,B transfers PALM to CAR IEA Bos taurus 17126 R-BTA-200410 https://reactome.org/PathwayBrowser/#/R-BTA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Bos taurus 17126 R-BTA-200424 https://reactome.org/PathwayBrowser/#/R-BTA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Bos taurus 17126 R-BTA-390281 https://reactome.org/PathwayBrowser/#/R-BTA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Bos taurus 17126 R-BTA-390284 https://reactome.org/PathwayBrowser/#/R-BTA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Bos taurus 17126 R-BTA-390291 https://reactome.org/PathwayBrowser/#/R-BTA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Bos taurus 17126 R-BTA-549297 https://reactome.org/PathwayBrowser/#/R-BTA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Bos taurus 17126 R-BTA-71261 https://reactome.org/PathwayBrowser/#/R-BTA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Bos taurus 17126 R-CEL-165026 https://reactome.org/PathwayBrowser/#/R-CEL-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Caenorhabditis elegans 17126 R-CEL-200406 https://reactome.org/PathwayBrowser/#/R-CEL-200406 CPT1A,B transfers PALM to CAR IEA Caenorhabditis elegans 17126 R-CEL-200410 https://reactome.org/PathwayBrowser/#/R-CEL-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Caenorhabditis elegans 17126 R-CEL-200424 https://reactome.org/PathwayBrowser/#/R-CEL-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Caenorhabditis elegans 17126 R-CEL-390281 https://reactome.org/PathwayBrowser/#/R-CEL-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Caenorhabditis elegans 17126 R-CEL-390284 https://reactome.org/PathwayBrowser/#/R-CEL-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Caenorhabditis elegans 17126 R-CEL-390291 https://reactome.org/PathwayBrowser/#/R-CEL-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Caenorhabditis elegans 17126 R-CEL-549297 https://reactome.org/PathwayBrowser/#/R-CEL-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 17126 R-CEL-71261 https://reactome.org/PathwayBrowser/#/R-CEL-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Caenorhabditis elegans 17126 R-CFA-165026 https://reactome.org/PathwayBrowser/#/R-CFA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Canis familiaris 17126 R-CFA-200406 https://reactome.org/PathwayBrowser/#/R-CFA-200406 CPT1A,B transfers PALM to CAR IEA Canis familiaris 17126 R-CFA-200410 https://reactome.org/PathwayBrowser/#/R-CFA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Canis familiaris 17126 R-CFA-200424 https://reactome.org/PathwayBrowser/#/R-CFA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Canis familiaris 17126 R-CFA-390281 https://reactome.org/PathwayBrowser/#/R-CFA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Canis familiaris 17126 R-CFA-390284 https://reactome.org/PathwayBrowser/#/R-CFA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Canis familiaris 17126 R-CFA-390291 https://reactome.org/PathwayBrowser/#/R-CFA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Canis familiaris 17126 R-CFA-549297 https://reactome.org/PathwayBrowser/#/R-CFA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Canis familiaris 17126 R-CFA-71261 https://reactome.org/PathwayBrowser/#/R-CFA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Canis familiaris 17126 R-DME-165026 https://reactome.org/PathwayBrowser/#/R-DME-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Drosophila melanogaster 17126 R-DME-200406 https://reactome.org/PathwayBrowser/#/R-DME-200406 CPT1A,B transfers PALM to CAR IEA Drosophila melanogaster 17126 R-DME-200410 https://reactome.org/PathwayBrowser/#/R-DME-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Drosophila melanogaster 17126 R-DME-200424 https://reactome.org/PathwayBrowser/#/R-DME-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Drosophila melanogaster 17126 R-DME-390281 https://reactome.org/PathwayBrowser/#/R-DME-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Drosophila melanogaster 17126 R-DME-390284 https://reactome.org/PathwayBrowser/#/R-DME-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Drosophila melanogaster 17126 R-DME-390291 https://reactome.org/PathwayBrowser/#/R-DME-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Drosophila melanogaster 17126 R-DME-549297 https://reactome.org/PathwayBrowser/#/R-DME-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 17126 R-DME-71261 https://reactome.org/PathwayBrowser/#/R-DME-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Drosophila melanogaster 17126 R-DRE-165026 https://reactome.org/PathwayBrowser/#/R-DRE-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Danio rerio 17126 R-DRE-200406 https://reactome.org/PathwayBrowser/#/R-DRE-200406 CPT1A,B transfers PALM to CAR IEA Danio rerio 17126 R-DRE-200410 https://reactome.org/PathwayBrowser/#/R-DRE-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Danio rerio 17126 R-DRE-200424 https://reactome.org/PathwayBrowser/#/R-DRE-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Danio rerio 17126 R-DRE-390281 https://reactome.org/PathwayBrowser/#/R-DRE-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Danio rerio 17126 R-DRE-390284 https://reactome.org/PathwayBrowser/#/R-DRE-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Danio rerio 17126 R-DRE-390291 https://reactome.org/PathwayBrowser/#/R-DRE-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Danio rerio 17126 R-DRE-549297 https://reactome.org/PathwayBrowser/#/R-DRE-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Danio rerio 17126 R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio 17126 R-GGA-165026 https://reactome.org/PathwayBrowser/#/R-GGA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Gallus gallus 17126 R-GGA-200406 https://reactome.org/PathwayBrowser/#/R-GGA-200406 CPT1A,B transfers PALM to CAR IEA Gallus gallus 17126 R-GGA-200410 https://reactome.org/PathwayBrowser/#/R-GGA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Gallus gallus 17126 R-GGA-200424 https://reactome.org/PathwayBrowser/#/R-GGA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Gallus gallus 17126 R-GGA-390281 https://reactome.org/PathwayBrowser/#/R-GGA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Gallus gallus 17126 R-GGA-390284 https://reactome.org/PathwayBrowser/#/R-GGA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Gallus gallus 17126 R-GGA-390291 https://reactome.org/PathwayBrowser/#/R-GGA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Gallus gallus 17126 R-GGA-549297 https://reactome.org/PathwayBrowser/#/R-GGA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Gallus gallus 17126 R-GGA-71261 https://reactome.org/PathwayBrowser/#/R-GGA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Gallus gallus 17126 R-HSA-164967 https://reactome.org/PathwayBrowser/#/R-HSA-164967 Unknown carnitine exporter transports CAR from the cytosol to the extracellular space TAS Homo sapiens 17126 R-HSA-165026 https://reactome.org/PathwayBrowser/#/R-HSA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol TAS Homo sapiens 17126 R-HSA-200406 https://reactome.org/PathwayBrowser/#/R-HSA-200406 CPT1A,B transfers PALM to CAR TAS Homo sapiens 17126 R-HSA-200410 https://reactome.org/PathwayBrowser/#/R-HSA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine TAS Homo sapiens 17126 R-HSA-200424 https://reactome.org/PathwayBrowser/#/R-HSA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane TAS Homo sapiens 17126 R-HSA-390281 https://reactome.org/PathwayBrowser/#/R-HSA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH TAS Homo sapiens 17126 R-HSA-390284 https://reactome.org/PathwayBrowser/#/R-HSA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH TAS Homo sapiens 17126 R-HSA-390291 https://reactome.org/PathwayBrowser/#/R-HSA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH TAS Homo sapiens 17126 R-HSA-549297 https://reactome.org/PathwayBrowser/#/R-HSA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol TAS Homo sapiens 17126 R-HSA-5625674 https://reactome.org/PathwayBrowser/#/R-HSA-5625674 Defective SLC22A5 does not cotransport CAR, Na+ from extracellular region to cytosol TAS Homo sapiens 17126 R-HSA-71261 https://reactome.org/PathwayBrowser/#/R-HSA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA TAS Homo sapiens 17126 R-HSA-8949399 https://reactome.org/PathwayBrowser/#/R-HSA-8949399 CAR translocates from the cytosol to the mitochondrial intermembrane space TAS Homo sapiens 17126 R-MMU-165026 https://reactome.org/PathwayBrowser/#/R-MMU-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Mus musculus 17126 R-MMU-200406 https://reactome.org/PathwayBrowser/#/R-MMU-200406 CPT1A,B transfers PALM to CAR IEA Mus musculus 17126 R-MMU-200410 https://reactome.org/PathwayBrowser/#/R-MMU-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Mus musculus 17126 R-MMU-200424 https://reactome.org/PathwayBrowser/#/R-MMU-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Mus musculus 17126 R-MMU-390281 https://reactome.org/PathwayBrowser/#/R-MMU-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Mus musculus 17126 R-MMU-390284 https://reactome.org/PathwayBrowser/#/R-MMU-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Mus musculus 17126 R-MMU-390291 https://reactome.org/PathwayBrowser/#/R-MMU-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Mus musculus 17126 R-MMU-549297 https://reactome.org/PathwayBrowser/#/R-MMU-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Mus musculus 17126 R-MMU-71261 https://reactome.org/PathwayBrowser/#/R-MMU-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Mus musculus 17126 R-RNO-165026 https://reactome.org/PathwayBrowser/#/R-RNO-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Rattus norvegicus 17126 R-RNO-200406 https://reactome.org/PathwayBrowser/#/R-RNO-200406 CPT1A,B transfers PALM to CAR IEA Rattus norvegicus 17126 R-RNO-200410 https://reactome.org/PathwayBrowser/#/R-RNO-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Rattus norvegicus 17126 R-RNO-200424 https://reactome.org/PathwayBrowser/#/R-RNO-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Rattus norvegicus 17126 R-RNO-390281 https://reactome.org/PathwayBrowser/#/R-RNO-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Rattus norvegicus 17126 R-RNO-390284 https://reactome.org/PathwayBrowser/#/R-RNO-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Rattus norvegicus 17126 R-RNO-390291 https://reactome.org/PathwayBrowser/#/R-RNO-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Rattus norvegicus 17126 R-RNO-549297 https://reactome.org/PathwayBrowser/#/R-RNO-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Rattus norvegicus 17126 R-RNO-71261 https://reactome.org/PathwayBrowser/#/R-RNO-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Rattus norvegicus 17126 R-SCE-200424 https://reactome.org/PathwayBrowser/#/R-SCE-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Saccharomyces cerevisiae 17126 R-SCE-71261 https://reactome.org/PathwayBrowser/#/R-SCE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Saccharomyces cerevisiae 17126 R-SPO-200424 https://reactome.org/PathwayBrowser/#/R-SPO-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Schizosaccharomyces pombe 17126 R-SSC-165026 https://reactome.org/PathwayBrowser/#/R-SSC-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Sus scrofa 17126 R-SSC-200406 https://reactome.org/PathwayBrowser/#/R-SSC-200406 CPT1A,B transfers PALM to CAR IEA Sus scrofa 17126 R-SSC-200410 https://reactome.org/PathwayBrowser/#/R-SSC-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Sus scrofa 17126 R-SSC-200424 https://reactome.org/PathwayBrowser/#/R-SSC-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Sus scrofa 17126 R-SSC-390281 https://reactome.org/PathwayBrowser/#/R-SSC-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Sus scrofa 17126 R-SSC-390284 https://reactome.org/PathwayBrowser/#/R-SSC-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Sus scrofa 17126 R-SSC-390291 https://reactome.org/PathwayBrowser/#/R-SSC-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Sus scrofa 17126 R-SSC-549297 https://reactome.org/PathwayBrowser/#/R-SSC-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Sus scrofa 17126 R-SSC-71261 https://reactome.org/PathwayBrowser/#/R-SSC-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Sus scrofa 17126 R-XTR-165026 https://reactome.org/PathwayBrowser/#/R-XTR-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Xenopus tropicalis 17126 R-XTR-200406 https://reactome.org/PathwayBrowser/#/R-XTR-200406 CPT1A,B transfers PALM to CAR IEA Xenopus tropicalis 17126 R-XTR-200410 https://reactome.org/PathwayBrowser/#/R-XTR-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Xenopus tropicalis 17126 R-XTR-200424 https://reactome.org/PathwayBrowser/#/R-XTR-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Xenopus tropicalis 17126 R-XTR-390281 https://reactome.org/PathwayBrowser/#/R-XTR-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Xenopus tropicalis 17126 R-XTR-390284 https://reactome.org/PathwayBrowser/#/R-XTR-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Xenopus tropicalis 17126 R-XTR-390291 https://reactome.org/PathwayBrowser/#/R-XTR-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Xenopus tropicalis 17126 R-XTR-549297 https://reactome.org/PathwayBrowser/#/R-XTR-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 17126 R-XTR-71261 https://reactome.org/PathwayBrowser/#/R-XTR-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Xenopus tropicalis 17137 R-BTA-9012721 https://reactome.org/PathwayBrowser/#/R-BTA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Bos taurus 17137 R-CEL-9012721 https://reactome.org/PathwayBrowser/#/R-CEL-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Caenorhabditis elegans 17137 R-CFA-9012721 https://reactome.org/PathwayBrowser/#/R-CFA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Canis familiaris 17137 R-DDI-9012721 https://reactome.org/PathwayBrowser/#/R-DDI-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Dictyostelium discoideum 17137 R-DRE-9012721 https://reactome.org/PathwayBrowser/#/R-DRE-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Danio rerio 17137 R-GGA-9012721 https://reactome.org/PathwayBrowser/#/R-GGA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Gallus gallus 17137 R-HSA-9012721 https://reactome.org/PathwayBrowser/#/R-HSA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR TAS Homo sapiens 17137 R-MMU-9012721 https://reactome.org/PathwayBrowser/#/R-MMU-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Mus musculus 17137 R-PFA-9012721 https://reactome.org/PathwayBrowser/#/R-PFA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Plasmodium falciparum 17137 R-RNO-9012721 https://reactome.org/PathwayBrowser/#/R-RNO-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Rattus norvegicus 17137 R-SCE-9012721 https://reactome.org/PathwayBrowser/#/R-SCE-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Saccharomyces cerevisiae 17137 R-SPO-9012721 https://reactome.org/PathwayBrowser/#/R-SPO-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Schizosaccharomyces pombe 17137 R-SSC-9012721 https://reactome.org/PathwayBrowser/#/R-SSC-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Sus scrofa 17137 R-XTR-9012721 https://reactome.org/PathwayBrowser/#/R-XTR-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Xenopus tropicalis 17140 R-BTA-5662466 https://reactome.org/PathwayBrowser/#/R-BTA-5662466 XYLB phosphorylates D-xylulose IEA Bos taurus 17140 R-BTA-5662471 https://reactome.org/PathwayBrowser/#/R-BTA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Bos taurus 17140 R-CEL-5662466 https://reactome.org/PathwayBrowser/#/R-CEL-5662466 XYLB phosphorylates D-xylulose IEA Caenorhabditis elegans 17140 R-CEL-5662471 https://reactome.org/PathwayBrowser/#/R-CEL-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Caenorhabditis elegans 17140 R-CFA-5662466 https://reactome.org/PathwayBrowser/#/R-CFA-5662466 XYLB phosphorylates D-xylulose IEA Canis familiaris 17140 R-CFA-5662471 https://reactome.org/PathwayBrowser/#/R-CFA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Canis familiaris 17140 R-DME-5662466 https://reactome.org/PathwayBrowser/#/R-DME-5662466 XYLB phosphorylates D-xylulose IEA Drosophila melanogaster 17140 R-DME-5662471 https://reactome.org/PathwayBrowser/#/R-DME-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Drosophila melanogaster 17140 R-DRE-5662466 https://reactome.org/PathwayBrowser/#/R-DRE-5662466 XYLB phosphorylates D-xylulose IEA Danio rerio 17140 R-GGA-5662466 https://reactome.org/PathwayBrowser/#/R-GGA-5662466 XYLB phosphorylates D-xylulose IEA Gallus gallus 17140 R-GGA-5662471 https://reactome.org/PathwayBrowser/#/R-GGA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Gallus gallus 17140 R-HSA-5662466 https://reactome.org/PathwayBrowser/#/R-HSA-5662466 XYLB phosphorylates D-xylulose TAS Homo sapiens 17140 R-HSA-5662471 https://reactome.org/PathwayBrowser/#/R-HSA-5662471 SORD tetramer oxidizes xylitol to D-xylulose TAS Homo sapiens 17140 R-MMU-5662466 https://reactome.org/PathwayBrowser/#/R-MMU-5662466 XYLB phosphorylates D-xylulose IEA Mus musculus 17140 R-MMU-5662471 https://reactome.org/PathwayBrowser/#/R-MMU-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Mus musculus 17140 R-RNO-5662466 https://reactome.org/PathwayBrowser/#/R-RNO-5662466 XYLB phosphorylates D-xylulose IEA Rattus norvegicus 17140 R-RNO-5662471 https://reactome.org/PathwayBrowser/#/R-RNO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Rattus norvegicus 17140 R-SCE-5662466 https://reactome.org/PathwayBrowser/#/R-SCE-5662466 XYLB phosphorylates D-xylulose IEA Saccharomyces cerevisiae 17140 R-SCE-5662471 https://reactome.org/PathwayBrowser/#/R-SCE-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Saccharomyces cerevisiae 17140 R-SPO-5662466 https://reactome.org/PathwayBrowser/#/R-SPO-5662466 XYLB phosphorylates D-xylulose IEA Schizosaccharomyces pombe 17140 R-SPO-5662471 https://reactome.org/PathwayBrowser/#/R-SPO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Schizosaccharomyces pombe 17140 R-SSC-5662466 https://reactome.org/PathwayBrowser/#/R-SSC-5662466 XYLB phosphorylates D-xylulose IEA Sus scrofa 17140 R-SSC-5662471 https://reactome.org/PathwayBrowser/#/R-SSC-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Sus scrofa 17140 R-XTR-5662466 https://reactome.org/PathwayBrowser/#/R-XTR-5662466 XYLB phosphorylates D-xylulose IEA Xenopus tropicalis 17140 R-XTR-5662471 https://reactome.org/PathwayBrowser/#/R-XTR-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Xenopus tropicalis 17151 R-BTA-5661240 https://reactome.org/PathwayBrowser/#/R-BTA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Bos taurus 17151 R-BTA-5662471 https://reactome.org/PathwayBrowser/#/R-BTA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Bos taurus 17151 R-CEL-5661240 https://reactome.org/PathwayBrowser/#/R-CEL-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Caenorhabditis elegans 17151 R-CEL-5662471 https://reactome.org/PathwayBrowser/#/R-CEL-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Caenorhabditis elegans 17151 R-CFA-5661240 https://reactome.org/PathwayBrowser/#/R-CFA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Canis familiaris 17151 R-CFA-5662471 https://reactome.org/PathwayBrowser/#/R-CFA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Canis familiaris 17151 R-DME-5661240 https://reactome.org/PathwayBrowser/#/R-DME-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Drosophila melanogaster 17151 R-DME-5662471 https://reactome.org/PathwayBrowser/#/R-DME-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Drosophila melanogaster 17151 R-DRE-5661240 https://reactome.org/PathwayBrowser/#/R-DRE-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Danio rerio 17151 R-GGA-5661240 https://reactome.org/PathwayBrowser/#/R-GGA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Gallus gallus 17151 R-GGA-5662471 https://reactome.org/PathwayBrowser/#/R-GGA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Gallus gallus 17151 R-HSA-5661240 https://reactome.org/PathwayBrowser/#/R-HSA-5661240 DCXR tetramer reduces L-xylulose to xylitol TAS Homo sapiens 17151 R-HSA-5662471 https://reactome.org/PathwayBrowser/#/R-HSA-5662471 SORD tetramer oxidizes xylitol to D-xylulose TAS Homo sapiens 17151 R-MMU-5661240 https://reactome.org/PathwayBrowser/#/R-MMU-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Mus musculus 17151 R-MMU-5662471 https://reactome.org/PathwayBrowser/#/R-MMU-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Mus musculus 17151 R-RNO-5661240 https://reactome.org/PathwayBrowser/#/R-RNO-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Rattus norvegicus 17151 R-RNO-5662471 https://reactome.org/PathwayBrowser/#/R-RNO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Rattus norvegicus 17151 R-SCE-5662471 https://reactome.org/PathwayBrowser/#/R-SCE-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Saccharomyces cerevisiae 17151 R-SPO-5662471 https://reactome.org/PathwayBrowser/#/R-SPO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Schizosaccharomyces pombe 17151 R-SSC-5661240 https://reactome.org/PathwayBrowser/#/R-SSC-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Sus scrofa 17151 R-SSC-5662471 https://reactome.org/PathwayBrowser/#/R-SSC-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Sus scrofa 17151 R-XTR-5661240 https://reactome.org/PathwayBrowser/#/R-XTR-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Xenopus tropicalis 17151 R-XTR-5662471 https://reactome.org/PathwayBrowser/#/R-XTR-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Xenopus tropicalis 17154 R-BTA-197250 https://reactome.org/PathwayBrowser/#/R-BTA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Bos taurus 17154 R-BTA-2187325 https://reactome.org/PathwayBrowser/#/R-BTA-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Bos taurus 17154 R-BTA-3371467 https://reactome.org/PathwayBrowser/#/R-BTA-3371467 SIRT1 deacetylates HSF1 IEA Bos taurus 17154 R-BTA-3640858 https://reactome.org/PathwayBrowser/#/R-BTA-3640858 Tankyrase ADP-ribosylates AXIN IEA Bos taurus 17154 R-BTA-427514 https://reactome.org/PathwayBrowser/#/R-BTA-427514 eNoSC deacetylates histone H3 IEA Bos taurus 17154 R-BTA-5359451 https://reactome.org/PathwayBrowser/#/R-BTA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Bos taurus 17154 R-BTA-5651723 https://reactome.org/PathwayBrowser/#/R-BTA-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Bos taurus 17154 R-BTA-5685953 https://reactome.org/PathwayBrowser/#/R-BTA-5685953 SIRT6 deacetylates RBBP8 IEA Bos taurus 17154 R-BTA-5687653 https://reactome.org/PathwayBrowser/#/R-BTA-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Bos taurus 17154 R-BTA-5688276 https://reactome.org/PathwayBrowser/#/R-BTA-5688276 SIRT4 transfers ADPRib to GLUD IEA Bos taurus 17154 R-BTA-5688289 https://reactome.org/PathwayBrowser/#/R-BTA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Bos taurus 17154 R-BTA-5688294 https://reactome.org/PathwayBrowser/#/R-BTA-5688294 SIRT5 deacetylates Cytochrome C IEA Bos taurus 17154 R-BTA-5696655 https://reactome.org/PathwayBrowser/#/R-BTA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Bos taurus 17154 R-BTA-8870346 https://reactome.org/PathwayBrowser/#/R-BTA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Bos taurus 17154 R-BTA-8938073 https://reactome.org/PathwayBrowser/#/R-BTA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Bos taurus 17154 R-BTA-8938076 https://reactome.org/PathwayBrowser/#/R-BTA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Bos taurus 17154 R-BTA-8948800 https://reactome.org/PathwayBrowser/#/R-BTA-8948800 TNKS and TNKS2 PARylate PTEN IEA Bos taurus 17154 R-BTA-9620532 https://reactome.org/PathwayBrowser/#/R-BTA-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Bos taurus 17154 R-BTA-9667952 https://reactome.org/PathwayBrowser/#/R-BTA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Bos taurus 17154 R-BTA-9854463 https://reactome.org/PathwayBrowser/#/R-BTA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Bos taurus 17154 R-BTA-9861626 https://reactome.org/PathwayBrowser/#/R-BTA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Bos taurus 17154 R-CEL-5359451 https://reactome.org/PathwayBrowser/#/R-CEL-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Caenorhabditis elegans 17154 R-CEL-5685953 https://reactome.org/PathwayBrowser/#/R-CEL-5685953 SIRT6 deacetylates RBBP8 IEA Caenorhabditis elegans 17154 R-CEL-5688276 https://reactome.org/PathwayBrowser/#/R-CEL-5688276 SIRT4 transfers ADPRib to GLUD IEA Caenorhabditis elegans 17154 R-CEL-5696655 https://reactome.org/PathwayBrowser/#/R-CEL-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Caenorhabditis elegans 17154 R-CEL-9620532 https://reactome.org/PathwayBrowser/#/R-CEL-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Caenorhabditis elegans 17154 R-CEL-9861626 https://reactome.org/PathwayBrowser/#/R-CEL-9861626 SIRT4 cleaves lipoyl from DLAT IEA Caenorhabditis elegans 17154 R-CFA-197250 https://reactome.org/PathwayBrowser/#/R-CFA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Canis familiaris 17154 R-CFA-2187325 https://reactome.org/PathwayBrowser/#/R-CFA-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Canis familiaris 17154 R-CFA-3371467 https://reactome.org/PathwayBrowser/#/R-CFA-3371467 SIRT1 deacetylates HSF1 IEA Canis familiaris 17154 R-CFA-3640858 https://reactome.org/PathwayBrowser/#/R-CFA-3640858 Tankyrase ADP-ribosylates AXIN IEA Canis familiaris 17154 R-CFA-427514 https://reactome.org/PathwayBrowser/#/R-CFA-427514 eNoSC deacetylates histone H3 IEA Canis familiaris 17154 R-CFA-5359451 https://reactome.org/PathwayBrowser/#/R-CFA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Canis familiaris 17154 R-CFA-5651723 https://reactome.org/PathwayBrowser/#/R-CFA-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Canis familiaris 17154 R-CFA-5685953 https://reactome.org/PathwayBrowser/#/R-CFA-5685953 SIRT6 deacetylates RBBP8 IEA Canis familiaris 17154 R-CFA-5688276 https://reactome.org/PathwayBrowser/#/R-CFA-5688276 SIRT4 transfers ADPRib to GLUD IEA Canis familiaris 17154 R-CFA-5688289 https://reactome.org/PathwayBrowser/#/R-CFA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Canis familiaris 17154 R-CFA-5696655 https://reactome.org/PathwayBrowser/#/R-CFA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Canis familiaris 17154 R-CFA-8870346 https://reactome.org/PathwayBrowser/#/R-CFA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Canis familiaris 17154 R-CFA-8938073 https://reactome.org/PathwayBrowser/#/R-CFA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Canis familiaris 17154 R-CFA-8938076 https://reactome.org/PathwayBrowser/#/R-CFA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Canis familiaris 17154 R-CFA-8948800 https://reactome.org/PathwayBrowser/#/R-CFA-8948800 TNKS and TNKS2 PARylate PTEN IEA Canis familiaris 17154 R-CFA-9620532 https://reactome.org/PathwayBrowser/#/R-CFA-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Canis familiaris 17154 R-CFA-9667952 https://reactome.org/PathwayBrowser/#/R-CFA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Canis familiaris 17154 R-CFA-9854463 https://reactome.org/PathwayBrowser/#/R-CFA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Canis familiaris 17154 R-CFA-9861626 https://reactome.org/PathwayBrowser/#/R-CFA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Canis familiaris 17154 R-DDI-427514 https://reactome.org/PathwayBrowser/#/R-DDI-427514 eNoSC deacetylates histone H3 IEA Dictyostelium discoideum 17154 R-DDI-5651723 https://reactome.org/PathwayBrowser/#/R-DDI-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Dictyostelium discoideum 17154 R-DDI-5688289 https://reactome.org/PathwayBrowser/#/R-DDI-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Dictyostelium discoideum 17154 R-DDI-5688294 https://reactome.org/PathwayBrowser/#/R-DDI-5688294 SIRT5 deacetylates Cytochrome C IEA Dictyostelium discoideum 17154 R-DDI-5696655 https://reactome.org/PathwayBrowser/#/R-DDI-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Dictyostelium discoideum 17154 R-DDI-8938073 https://reactome.org/PathwayBrowser/#/R-DDI-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Dictyostelium discoideum 17154 R-DME-2187325 https://reactome.org/PathwayBrowser/#/R-DME-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Drosophila melanogaster 17154 R-DME-427514 https://reactome.org/PathwayBrowser/#/R-DME-427514 eNoSC deacetylates histone H3 IEA Drosophila melanogaster 17154 R-DME-5687653 https://reactome.org/PathwayBrowser/#/R-DME-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Drosophila melanogaster 17154 R-DME-5688276 https://reactome.org/PathwayBrowser/#/R-DME-5688276 SIRT4 transfers ADPRib to GLUD IEA Drosophila melanogaster 17154 R-DME-5696655 https://reactome.org/PathwayBrowser/#/R-DME-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Drosophila melanogaster 17154 R-DME-8938073 https://reactome.org/PathwayBrowser/#/R-DME-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Drosophila melanogaster 17154 R-DME-9620532 https://reactome.org/PathwayBrowser/#/R-DME-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Drosophila melanogaster 17154 R-DME-9667952 https://reactome.org/PathwayBrowser/#/R-DME-9667952 ANKLE2 is deacetylated by SIRT2 IEA Drosophila melanogaster 17154 R-DME-9861626 https://reactome.org/PathwayBrowser/#/R-DME-9861626 SIRT4 cleaves lipoyl from DLAT IEA Drosophila melanogaster 17154 R-DRE-5359451 https://reactome.org/PathwayBrowser/#/R-DRE-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Danio rerio 17154 R-DRE-5651723 https://reactome.org/PathwayBrowser/#/R-DRE-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Danio rerio 17154 R-DRE-5685953 https://reactome.org/PathwayBrowser/#/R-DRE-5685953 SIRT6 deacetylates RBBP8 IEA Danio rerio 17154 R-DRE-5688276 https://reactome.org/PathwayBrowser/#/R-DRE-5688276 SIRT4 transfers ADPRib to GLUD IEA Danio rerio 17154 R-DRE-5688294 https://reactome.org/PathwayBrowser/#/R-DRE-5688294 SIRT5 deacetylates Cytochrome C IEA Danio rerio 17154 R-DRE-5696655 https://reactome.org/PathwayBrowser/#/R-DRE-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Danio rerio 17154 R-DRE-8938073 https://reactome.org/PathwayBrowser/#/R-DRE-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Danio rerio 17154 R-DRE-9667952 https://reactome.org/PathwayBrowser/#/R-DRE-9667952 ANKLE2 is deacetylated by SIRT2 IEA Danio rerio 17154 R-DRE-9861626 https://reactome.org/PathwayBrowser/#/R-DRE-9861626 SIRT4 cleaves lipoyl from DLAT IEA Danio rerio 17154 R-GGA-197250 https://reactome.org/PathwayBrowser/#/R-GGA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Gallus gallus 17154 R-GGA-3371467 https://reactome.org/PathwayBrowser/#/R-GGA-3371467 SIRT1 deacetylates HSF1 IEA Gallus gallus 17154 R-GGA-3640858 https://reactome.org/PathwayBrowser/#/R-GGA-3640858 Tankyrase ADP-ribosylates AXIN IEA Gallus gallus 17154 R-GGA-5685953 https://reactome.org/PathwayBrowser/#/R-GGA-5685953 SIRT6 deacetylates RBBP8 IEA Gallus gallus 17154 R-GGA-5687653 https://reactome.org/PathwayBrowser/#/R-GGA-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Gallus gallus 17154 R-GGA-5688276 https://reactome.org/PathwayBrowser/#/R-GGA-5688276 SIRT4 transfers ADPRib to GLUD IEA Gallus gallus 17154 R-GGA-5688289 https://reactome.org/PathwayBrowser/#/R-GGA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Gallus gallus 17154 R-GGA-5688294 https://reactome.org/PathwayBrowser/#/R-GGA-5688294 SIRT5 deacetylates Cytochrome C IEA Gallus gallus 17154 R-GGA-5696655 https://reactome.org/PathwayBrowser/#/R-GGA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Gallus gallus 17154 R-GGA-8870346 https://reactome.org/PathwayBrowser/#/R-GGA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Gallus gallus 17154 R-GGA-8938073 https://reactome.org/PathwayBrowser/#/R-GGA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Gallus gallus 17154 R-GGA-8938076 https://reactome.org/PathwayBrowser/#/R-GGA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Gallus gallus 17154 R-GGA-8948800 https://reactome.org/PathwayBrowser/#/R-GGA-8948800 TNKS and TNKS2 PARylate PTEN IEA Gallus gallus 17154 R-GGA-9620532 https://reactome.org/PathwayBrowser/#/R-GGA-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Gallus gallus 17154 R-GGA-9667952 https://reactome.org/PathwayBrowser/#/R-GGA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Gallus gallus 17154 R-GGA-9854463 https://reactome.org/PathwayBrowser/#/R-GGA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Gallus gallus 17154 R-GGA-9861626 https://reactome.org/PathwayBrowser/#/R-GGA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Gallus gallus 17154 R-HSA-197250 https://reactome.org/PathwayBrowser/#/R-HSA-197250 NAMPT transfers PRIB to NAM to form NAMN TAS Homo sapiens 17154 R-HSA-2187325 https://reactome.org/PathwayBrowser/#/R-HSA-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 TAS Homo sapiens 17154 R-HSA-2408544 https://reactome.org/PathwayBrowser/#/R-HSA-2408544 AdoSeMet is converted to AdeSeHCys by MetTrans(1) IEA Homo sapiens 17154 R-HSA-3371467 https://reactome.org/PathwayBrowser/#/R-HSA-3371467 SIRT1 deacetylates HSF1 TAS Homo sapiens 17154 R-HSA-3640858 https://reactome.org/PathwayBrowser/#/R-HSA-3640858 Tankyrase ADP-ribosylates AXIN TAS Homo sapiens 17154 R-HSA-427514 https://reactome.org/PathwayBrowser/#/R-HSA-427514 eNoSC deacetylates histone H3 TAS Homo sapiens 17154 R-HSA-5211239 https://reactome.org/PathwayBrowser/#/R-HSA-5211239 SIRT1 deacetylates TAF1B in SL1 complex IEA Homo sapiens 17154 R-HSA-5336421 https://reactome.org/PathwayBrowser/#/R-HSA-5336421 DT fragment A ADP-ribosylates target cell EEF TAS Homo sapiens 17154 R-HSA-5359451 https://reactome.org/PathwayBrowser/#/R-HSA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA TAS Homo sapiens 17154 R-HSA-5651723 https://reactome.org/PathwayBrowser/#/R-HSA-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate TAS Homo sapiens 17154 R-HSA-5685953 https://reactome.org/PathwayBrowser/#/R-HSA-5685953 SIRT6 deacetylates RBBP8 TAS Homo sapiens 17154 R-HSA-5687653 https://reactome.org/PathwayBrowser/#/R-HSA-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate TAS Homo sapiens 17154 R-HSA-5688276 https://reactome.org/PathwayBrowser/#/R-HSA-5688276 SIRT4 transfers ADPRib to GLUD TAS Homo sapiens 17154 R-HSA-5688289 https://reactome.org/PathwayBrowser/#/R-HSA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 TAS Homo sapiens 17154 R-HSA-5688294 https://reactome.org/PathwayBrowser/#/R-HSA-5688294 SIRT5 deacetylates Cytochrome C TAS Homo sapiens 17154 R-HSA-5696655 https://reactome.org/PathwayBrowser/#/R-HSA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates TAS Homo sapiens 17154 R-HSA-8870346 https://reactome.org/PathwayBrowser/#/R-HSA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose TAS Homo sapiens 17154 R-HSA-8938073 https://reactome.org/PathwayBrowser/#/R-HSA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) TAS Homo sapiens 17154 R-HSA-8938076 https://reactome.org/PathwayBrowser/#/R-HSA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose TAS Homo sapiens 17154 R-HSA-8948800 https://reactome.org/PathwayBrowser/#/R-HSA-8948800 TNKS and TNKS2 PARylate PTEN TAS Homo sapiens 17154 R-HSA-9620532 https://reactome.org/PathwayBrowser/#/R-HSA-9620532 SIRT1,SIRT3 deacetylate FOXO3 TAS Homo sapiens 17154 R-HSA-9626962 https://reactome.org/PathwayBrowser/#/R-HSA-9626962 SIRT1 deacetylates FOXO1 IEA Homo sapiens 17154 R-HSA-9637699 https://reactome.org/PathwayBrowser/#/R-HSA-9637699 CpnT hydrolyses NAD+ TAS Homo sapiens 17154 R-HSA-9667952 https://reactome.org/PathwayBrowser/#/R-HSA-9667952 ANKLE2 is deacetylated by SIRT2 TAS Homo sapiens 17154 R-HSA-9686061 https://reactome.org/PathwayBrowser/#/R-HSA-9686061 Nucleoprotein is ADP-ribosylated TAS Homo sapiens 17154 R-HSA-9729279 https://reactome.org/PathwayBrowser/#/R-HSA-9729279 Nucleoprotein is ADP-ribosylated IEA Homo sapiens 17154 R-HSA-9854463 https://reactome.org/PathwayBrowser/#/R-HSA-9854463 SIRT3 deacetylates AcK-IDH2 dimer TAS Homo sapiens 17154 R-HSA-9861626 https://reactome.org/PathwayBrowser/#/R-HSA-9861626 SIRT4 cleaves lipoyl from DLAT TAS Homo sapiens 17154 R-MMU-197250 https://reactome.org/PathwayBrowser/#/R-MMU-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Mus musculus 17154 R-MMU-2187325 https://reactome.org/PathwayBrowser/#/R-MMU-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Mus musculus 17154 R-MMU-3371467 https://reactome.org/PathwayBrowser/#/R-MMU-3371467 SIRT1 deacetylates HSF1 IEA Mus musculus 17154 R-MMU-3640858 https://reactome.org/PathwayBrowser/#/R-MMU-3640858 Tankyrase ADP-ribosylates AXIN IEA Mus musculus 17154 R-MMU-5211233 https://reactome.org/PathwayBrowser/#/R-MMU-5211233 Sirt1 deacetylates Taf1b in SL1 complex TAS Mus musculus 17154 R-MMU-5359451 https://reactome.org/PathwayBrowser/#/R-MMU-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Mus musculus 17154 R-MMU-5651723 https://reactome.org/PathwayBrowser/#/R-MMU-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Mus musculus 17154 R-MMU-5685953 https://reactome.org/PathwayBrowser/#/R-MMU-5685953 SIRT6 deacetylates RBBP8 IEA Mus musculus 17154 R-MMU-5687653 https://reactome.org/PathwayBrowser/#/R-MMU-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Mus musculus 17154 R-MMU-5688276 https://reactome.org/PathwayBrowser/#/R-MMU-5688276 SIRT4 transfers ADPRib to GLUD IEA Mus musculus 17154 R-MMU-5688289 https://reactome.org/PathwayBrowser/#/R-MMU-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Mus musculus 17154 R-MMU-5688294 https://reactome.org/PathwayBrowser/#/R-MMU-5688294 SIRT5 deacetylates Cytochrome C IEA Mus musculus 17154 R-MMU-5696655 https://reactome.org/PathwayBrowser/#/R-MMU-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Mus musculus 17154 R-MMU-8870346 https://reactome.org/PathwayBrowser/#/R-MMU-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Mus musculus 17154 R-MMU-8938073 https://reactome.org/PathwayBrowser/#/R-MMU-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Mus musculus 17154 R-MMU-8938076 https://reactome.org/PathwayBrowser/#/R-MMU-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Mus musculus 17154 R-MMU-8948800 https://reactome.org/PathwayBrowser/#/R-MMU-8948800 TNKS and TNKS2 PARylate PTEN IEA Mus musculus 17154 R-MMU-9620532 https://reactome.org/PathwayBrowser/#/R-MMU-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Mus musculus 17154 R-MMU-9626966 https://reactome.org/PathwayBrowser/#/R-MMU-9626966 Sirt1 deacetylates Foxo1 TAS Mus musculus 17154 R-MMU-9667952 https://reactome.org/PathwayBrowser/#/R-MMU-9667952 ANKLE2 is deacetylated by SIRT2 IEA Mus musculus 17154 R-MMU-9854463 https://reactome.org/PathwayBrowser/#/R-MMU-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Mus musculus 17154 R-MMU-9861626 https://reactome.org/PathwayBrowser/#/R-MMU-9861626 SIRT4 cleaves lipoyl from DLAT IEA Mus musculus 17154 R-PFA-5688294 https://reactome.org/PathwayBrowser/#/R-PFA-5688294 SIRT5 deacetylates Cytochrome C IEA Plasmodium falciparum 17154 R-PFA-5696655 https://reactome.org/PathwayBrowser/#/R-PFA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Plasmodium falciparum 17154 R-RNO-197250 https://reactome.org/PathwayBrowser/#/R-RNO-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Rattus norvegicus 17154 R-RNO-2187325 https://reactome.org/PathwayBrowser/#/R-RNO-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Rattus norvegicus 17154 R-RNO-2408545 https://reactome.org/PathwayBrowser/#/R-RNO-2408545 AdoSeMet is converted to AdeSeHCys by MetTrans(2) TAS Rattus norvegicus 17154 R-RNO-3371467 https://reactome.org/PathwayBrowser/#/R-RNO-3371467 SIRT1 deacetylates HSF1 IEA Rattus norvegicus 17154 R-RNO-3640858 https://reactome.org/PathwayBrowser/#/R-RNO-3640858 Tankyrase ADP-ribosylates AXIN IEA Rattus norvegicus 17154 R-RNO-427514 https://reactome.org/PathwayBrowser/#/R-RNO-427514 eNoSC deacetylates histone H3 IEA Rattus norvegicus 17154 R-RNO-5359451 https://reactome.org/PathwayBrowser/#/R-RNO-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Rattus norvegicus 17154 R-RNO-5651723 https://reactome.org/PathwayBrowser/#/R-RNO-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Rattus norvegicus 17154 R-RNO-5685953 https://reactome.org/PathwayBrowser/#/R-RNO-5685953 SIRT6 deacetylates RBBP8 IEA Rattus norvegicus 17154 R-RNO-5687653 https://reactome.org/PathwayBrowser/#/R-RNO-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Rattus norvegicus 17154 R-RNO-5688276 https://reactome.org/PathwayBrowser/#/R-RNO-5688276 SIRT4 transfers ADPRib to GLUD IEA Rattus norvegicus 17154 R-RNO-5688289 https://reactome.org/PathwayBrowser/#/R-RNO-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Rattus norvegicus 17154 R-RNO-5688294 https://reactome.org/PathwayBrowser/#/R-RNO-5688294 SIRT5 deacetylates Cytochrome C IEA Rattus norvegicus 17154 R-RNO-5696655 https://reactome.org/PathwayBrowser/#/R-RNO-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Rattus norvegicus 17154 R-RNO-8870346 https://reactome.org/PathwayBrowser/#/R-RNO-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Rattus norvegicus 17154 R-RNO-8938073 https://reactome.org/PathwayBrowser/#/R-RNO-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Rattus norvegicus 17154 R-RNO-8938076 https://reactome.org/PathwayBrowser/#/R-RNO-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Rattus norvegicus 17154 R-RNO-8948800 https://reactome.org/PathwayBrowser/#/R-RNO-8948800 TNKS and TNKS2 PARylate PTEN IEA Rattus norvegicus 17154 R-RNO-9620532 https://reactome.org/PathwayBrowser/#/R-RNO-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Rattus norvegicus 17154 R-RNO-9667952 https://reactome.org/PathwayBrowser/#/R-RNO-9667952 ANKLE2 is deacetylated by SIRT2 IEA Rattus norvegicus 17154 R-RNO-9854463 https://reactome.org/PathwayBrowser/#/R-RNO-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Rattus norvegicus 17154 R-RNO-9861626 https://reactome.org/PathwayBrowser/#/R-RNO-9861626 SIRT4 cleaves lipoyl from DLAT IEA Rattus norvegicus 17154 R-SCE-427514 https://reactome.org/PathwayBrowser/#/R-SCE-427514 eNoSC deacetylates histone H3 IEA Saccharomyces cerevisiae 17154 R-SCE-5688289 https://reactome.org/PathwayBrowser/#/R-SCE-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Saccharomyces cerevisiae 17154 R-SPO-427514 https://reactome.org/PathwayBrowser/#/R-SPO-427514 eNoSC deacetylates histone H3 IEA Schizosaccharomyces pombe 17154 R-SPO-5688289 https://reactome.org/PathwayBrowser/#/R-SPO-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Schizosaccharomyces pombe 17154 R-SSC-197250 https://reactome.org/PathwayBrowser/#/R-SSC-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Sus scrofa 17154 R-SSC-2187325 https://reactome.org/PathwayBrowser/#/R-SSC-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Sus scrofa 17154 R-SSC-3371467 https://reactome.org/PathwayBrowser/#/R-SSC-3371467 SIRT1 deacetylates HSF1 IEA Sus scrofa 17154 R-SSC-3640858 https://reactome.org/PathwayBrowser/#/R-SSC-3640858 Tankyrase ADP-ribosylates AXIN IEA Sus scrofa 17154 R-SSC-427514 https://reactome.org/PathwayBrowser/#/R-SSC-427514 eNoSC deacetylates histone H3 IEA Sus scrofa 17154 R-SSC-5359451 https://reactome.org/PathwayBrowser/#/R-SSC-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Sus scrofa 17154 R-SSC-5651723 https://reactome.org/PathwayBrowser/#/R-SSC-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Sus scrofa 17154 R-SSC-5685953 https://reactome.org/PathwayBrowser/#/R-SSC-5685953 SIRT6 deacetylates RBBP8 IEA Sus scrofa 17154 R-SSC-5687653 https://reactome.org/PathwayBrowser/#/R-SSC-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Sus scrofa 17154 R-SSC-5688276 https://reactome.org/PathwayBrowser/#/R-SSC-5688276 SIRT4 transfers ADPRib to GLUD IEA Sus scrofa 17154 R-SSC-5688289 https://reactome.org/PathwayBrowser/#/R-SSC-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Sus scrofa 17154 R-SSC-5688294 https://reactome.org/PathwayBrowser/#/R-SSC-5688294 SIRT5 deacetylates Cytochrome C IEA Sus scrofa 17154 R-SSC-5696655 https://reactome.org/PathwayBrowser/#/R-SSC-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Sus scrofa 17154 R-SSC-8870346 https://reactome.org/PathwayBrowser/#/R-SSC-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Sus scrofa 17154 R-SSC-8938073 https://reactome.org/PathwayBrowser/#/R-SSC-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Sus scrofa 17154 R-SSC-8938076 https://reactome.org/PathwayBrowser/#/R-SSC-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Sus scrofa 17154 R-SSC-8948800 https://reactome.org/PathwayBrowser/#/R-SSC-8948800 TNKS and TNKS2 PARylate PTEN IEA Sus scrofa 17154 R-SSC-9620532 https://reactome.org/PathwayBrowser/#/R-SSC-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Sus scrofa 17154 R-SSC-9667952 https://reactome.org/PathwayBrowser/#/R-SSC-9667952 ANKLE2 is deacetylated by SIRT2 IEA Sus scrofa 17154 R-SSC-9854463 https://reactome.org/PathwayBrowser/#/R-SSC-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Sus scrofa 17154 R-SSC-9861626 https://reactome.org/PathwayBrowser/#/R-SSC-9861626 SIRT4 cleaves lipoyl from DLAT IEA Sus scrofa 17154 R-XTR-197250 https://reactome.org/PathwayBrowser/#/R-XTR-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Xenopus tropicalis 17154 R-XTR-5359451 https://reactome.org/PathwayBrowser/#/R-XTR-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Xenopus tropicalis 17154 R-XTR-5651723 https://reactome.org/PathwayBrowser/#/R-XTR-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Xenopus tropicalis 17154 R-XTR-5685953 https://reactome.org/PathwayBrowser/#/R-XTR-5685953 SIRT6 deacetylates RBBP8 IEA Xenopus tropicalis 17154 R-XTR-5688276 https://reactome.org/PathwayBrowser/#/R-XTR-5688276 SIRT4 transfers ADPRib to GLUD IEA Xenopus tropicalis 17154 R-XTR-5688294 https://reactome.org/PathwayBrowser/#/R-XTR-5688294 SIRT5 deacetylates Cytochrome C IEA Xenopus tropicalis 17154 R-XTR-5696655 https://reactome.org/PathwayBrowser/#/R-XTR-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Xenopus tropicalis 17154 R-XTR-8870346 https://reactome.org/PathwayBrowser/#/R-XTR-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Xenopus tropicalis 17154 R-XTR-8938073 https://reactome.org/PathwayBrowser/#/R-XTR-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Xenopus tropicalis 17154 R-XTR-8938076 https://reactome.org/PathwayBrowser/#/R-XTR-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Xenopus tropicalis 17154 R-XTR-9861626 https://reactome.org/PathwayBrowser/#/R-XTR-9861626 SIRT4 cleaves lipoyl from DLAT IEA Xenopus tropicalis 17158 R-BTA-5694071 https://reactome.org/PathwayBrowser/#/R-BTA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Bos taurus 17158 R-CFA-5694071 https://reactome.org/PathwayBrowser/#/R-CFA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Canis familiaris 17158 R-DME-5694071 https://reactome.org/PathwayBrowser/#/R-DME-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Drosophila melanogaster 17158 R-DRE-5694071 https://reactome.org/PathwayBrowser/#/R-DRE-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Danio rerio 17158 R-GGA-5694071 https://reactome.org/PathwayBrowser/#/R-GGA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Gallus gallus 17158 R-HSA-5694071 https://reactome.org/PathwayBrowser/#/R-HSA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH TAS Homo sapiens 17158 R-MMU-5694071 https://reactome.org/PathwayBrowser/#/R-MMU-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Mus musculus 17158 R-PFA-5694071 https://reactome.org/PathwayBrowser/#/R-PFA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Plasmodium falciparum 17158 R-RNO-5694071 https://reactome.org/PathwayBrowser/#/R-RNO-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Rattus norvegicus 17158 R-SCE-5694071 https://reactome.org/PathwayBrowser/#/R-SCE-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Saccharomyces cerevisiae 17158 R-SPO-5694071 https://reactome.org/PathwayBrowser/#/R-SPO-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Schizosaccharomyces pombe 17158 R-SSC-5694071 https://reactome.org/PathwayBrowser/#/R-SSC-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Sus scrofa 17158 R-XTR-5694071 https://reactome.org/PathwayBrowser/#/R-XTR-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Xenopus tropicalis 17168 R-BTA-6807052 https://reactome.org/PathwayBrowser/#/R-BTA-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Bos taurus 17168 R-BTA-6807053 https://reactome.org/PathwayBrowser/#/R-BTA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Bos taurus 17168 R-CFA-6807052 https://reactome.org/PathwayBrowser/#/R-CFA-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Canis familiaris 17168 R-CFA-6807053 https://reactome.org/PathwayBrowser/#/R-CFA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Canis familiaris 17168 R-DDI-6807052 https://reactome.org/PathwayBrowser/#/R-DDI-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Dictyostelium discoideum 17168 R-DRE-6807052 https://reactome.org/PathwayBrowser/#/R-DRE-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Danio rerio 17168 R-DRE-6807053 https://reactome.org/PathwayBrowser/#/R-DRE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Danio rerio 17168 R-GGA-6807052 https://reactome.org/PathwayBrowser/#/R-GGA-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Gallus gallus 17168 R-GGA-6807053 https://reactome.org/PathwayBrowser/#/R-GGA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Gallus gallus 17168 R-HSA-6807052 https://reactome.org/PathwayBrowser/#/R-HSA-6807052 EBP isomerizes ZYMSTNL to LTHSOL TAS Homo sapiens 17168 R-HSA-6807053 https://reactome.org/PathwayBrowser/#/R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL TAS Homo sapiens 17168 R-MMU-6807052 https://reactome.org/PathwayBrowser/#/R-MMU-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Mus musculus 17168 R-MMU-6807053 https://reactome.org/PathwayBrowser/#/R-MMU-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Mus musculus 17168 R-RNO-6807052 https://reactome.org/PathwayBrowser/#/R-RNO-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Rattus norvegicus 17168 R-RNO-6807053 https://reactome.org/PathwayBrowser/#/R-RNO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Rattus norvegicus 17168 R-SCE-6807053 https://reactome.org/PathwayBrowser/#/R-SCE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Saccharomyces cerevisiae 17168 R-SPO-6807053 https://reactome.org/PathwayBrowser/#/R-SPO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Schizosaccharomyces pombe 17168 R-SSC-6807052 https://reactome.org/PathwayBrowser/#/R-SSC-6807052 EBP isomerizes ZYMSTNL to LTHSOL IEA Sus scrofa 17168 R-SSC-6807053 https://reactome.org/PathwayBrowser/#/R-SSC-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Sus scrofa 17168 R-XTR-6807053 https://reactome.org/PathwayBrowser/#/R-XTR-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Xenopus tropicalis 171681 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 171681 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 171681 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 171681 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 171681 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 171681 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 171681 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 171681 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 171681 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 17169 R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 17169 R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 17169 R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 17169 R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 17169 R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 17169 R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 17169 R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa 17169 R-XTR-5696183 https://reactome.org/PathwayBrowser/#/R-XTR-5696183 AOC3 deaminates BZAM IEA Xenopus tropicalis 17170 R-BTA-5693373 https://reactome.org/PathwayBrowser/#/R-BTA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Bos taurus 17170 R-CFA-5693373 https://reactome.org/PathwayBrowser/#/R-CFA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Canis familiaris 17170 R-DME-5693373 https://reactome.org/PathwayBrowser/#/R-DME-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Drosophila melanogaster 17170 R-GGA-5693373 https://reactome.org/PathwayBrowser/#/R-GGA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Gallus gallus 17170 R-HSA-5693373 https://reactome.org/PathwayBrowser/#/R-HSA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit TAS Homo sapiens 17170 R-MMU-5693373 https://reactome.org/PathwayBrowser/#/R-MMU-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Mus musculus 17170 R-RNO-5693373 https://reactome.org/PathwayBrowser/#/R-RNO-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Rattus norvegicus 17170 R-XTR-5693373 https://reactome.org/PathwayBrowser/#/R-XTR-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Xenopus tropicalis 17172 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 17172 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 17172 R-BTA-109671 https://reactome.org/PathwayBrowser/#/R-BTA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Bos taurus 17172 R-BTA-112034 https://reactome.org/PathwayBrowser/#/R-BTA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Bos taurus 17172 R-BTA-74207 https://reactome.org/PathwayBrowser/#/R-BTA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Bos taurus 17172 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 17172 R-BTA-74249 https://reactome.org/PathwayBrowser/#/R-BTA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Bos taurus 17172 R-BTA-9824732 https://reactome.org/PathwayBrowser/#/R-BTA-9824732 G or G analog binds C-ter TLR7 dimer IEA Bos taurus 17172 R-CEL-112034 https://reactome.org/PathwayBrowser/#/R-CEL-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Caenorhabditis elegans 17172 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 17172 R-CEL-74249 https://reactome.org/PathwayBrowser/#/R-CEL-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Caenorhabditis elegans 17172 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 17172 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 17172 R-CFA-109671 https://reactome.org/PathwayBrowser/#/R-CFA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Canis familiaris 17172 R-CFA-112034 https://reactome.org/PathwayBrowser/#/R-CFA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Canis familiaris 17172 R-CFA-74207 https://reactome.org/PathwayBrowser/#/R-CFA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Canis familiaris 17172 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 17172 R-CFA-74249 https://reactome.org/PathwayBrowser/#/R-CFA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Canis familiaris 17172 R-CFA-9824732 https://reactome.org/PathwayBrowser/#/R-CFA-9824732 G or G analog binds C-ter TLR7 dimer IEA Canis familiaris 17172 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 17172 R-DME-112034 https://reactome.org/PathwayBrowser/#/R-DME-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Drosophila melanogaster 17172 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 17172 R-DME-74249 https://reactome.org/PathwayBrowser/#/R-DME-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Drosophila melanogaster 17172 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 17172 R-DRE-109671 https://reactome.org/PathwayBrowser/#/R-DRE-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Danio rerio 17172 R-DRE-112034 https://reactome.org/PathwayBrowser/#/R-DRE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Danio rerio 17172 R-DRE-74207 https://reactome.org/PathwayBrowser/#/R-DRE-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Danio rerio 17172 R-DRE-74249 https://reactome.org/PathwayBrowser/#/R-DRE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Danio rerio 17172 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 17172 R-GGA-109671 https://reactome.org/PathwayBrowser/#/R-GGA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Gallus gallus 17172 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 17172 R-GGA-9824732 https://reactome.org/PathwayBrowser/#/R-GGA-9824732 G or G analog binds C-ter TLR7 dimer IEA Gallus gallus 17172 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 17172 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 17172 R-HSA-109671 https://reactome.org/PathwayBrowser/#/R-HSA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) TAS Homo sapiens 17172 R-HSA-112034 https://reactome.org/PathwayBrowser/#/R-HSA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine TAS Homo sapiens 17172 R-HSA-6789114 https://reactome.org/PathwayBrowser/#/R-HSA-6789114 Hydroxyl radical reacts with the base and sugar moiety of DNA TAS Homo sapiens 17172 R-HSA-74207 https://reactome.org/PathwayBrowser/#/R-HSA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) TAS Homo sapiens 17172 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 17172 R-HSA-74249 https://reactome.org/PathwayBrowser/#/R-HSA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 17172 R-HSA-9735789 https://reactome.org/PathwayBrowser/#/R-HSA-9735789 Defective PNP does not convert (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 17172 R-HSA-9824732 https://reactome.org/PathwayBrowser/#/R-HSA-9824732 G or G analog binds C-ter TLR7 dimer TAS Homo sapiens 17172 R-HSA-9824849 https://reactome.org/PathwayBrowser/#/R-HSA-9824849 G or G analog binds C-ter TLR7 GoF variant TAS Homo sapiens 17172 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 17172 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 17172 R-MMU-109671 https://reactome.org/PathwayBrowser/#/R-MMU-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Mus musculus 17172 R-MMU-112034 https://reactome.org/PathwayBrowser/#/R-MMU-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Mus musculus 17172 R-MMU-74207 https://reactome.org/PathwayBrowser/#/R-MMU-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Mus musculus 17172 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 17172 R-MMU-74249 https://reactome.org/PathwayBrowser/#/R-MMU-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Mus musculus 17172 R-MMU-9824732 https://reactome.org/PathwayBrowser/#/R-MMU-9824732 G or G analog binds C-ter TLR7 dimer IEA Mus musculus 17172 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 17172 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 17172 R-RNO-109671 https://reactome.org/PathwayBrowser/#/R-RNO-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Rattus norvegicus 17172 R-RNO-112034 https://reactome.org/PathwayBrowser/#/R-RNO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Rattus norvegicus 17172 R-RNO-74207 https://reactome.org/PathwayBrowser/#/R-RNO-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Rattus norvegicus 17172 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 17172 R-RNO-74249 https://reactome.org/PathwayBrowser/#/R-RNO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Rattus norvegicus 17172 R-RNO-9824732 https://reactome.org/PathwayBrowser/#/R-RNO-9824732 G or G analog binds C-ter TLR7 dimer IEA Rattus norvegicus 17172 R-SCE-112034 https://reactome.org/PathwayBrowser/#/R-SCE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Saccharomyces cerevisiae 17172 R-SCE-74249 https://reactome.org/PathwayBrowser/#/R-SCE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Saccharomyces cerevisiae 17172 R-SPO-112034 https://reactome.org/PathwayBrowser/#/R-SPO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Schizosaccharomyces pombe 17172 R-SPO-74249 https://reactome.org/PathwayBrowser/#/R-SPO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Schizosaccharomyces pombe 17172 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 17172 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 17172 R-SSC-112034 https://reactome.org/PathwayBrowser/#/R-SSC-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Sus scrofa 17172 R-SSC-74207 https://reactome.org/PathwayBrowser/#/R-SSC-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Sus scrofa 17172 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 17172 R-SSC-74249 https://reactome.org/PathwayBrowser/#/R-SSC-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Sus scrofa 17172 R-SSC-9824732 https://reactome.org/PathwayBrowser/#/R-SSC-9824732 G or G analog binds C-ter TLR7 dimer IEA Sus scrofa 17172 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 17172 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 17172 R-XTR-109671 https://reactome.org/PathwayBrowser/#/R-XTR-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Xenopus tropicalis 17172 R-XTR-112034 https://reactome.org/PathwayBrowser/#/R-XTR-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Xenopus tropicalis 17172 R-XTR-74207 https://reactome.org/PathwayBrowser/#/R-XTR-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Xenopus tropicalis 17172 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 17172 R-XTR-74249 https://reactome.org/PathwayBrowser/#/R-XTR-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Xenopus tropicalis 17172 R-XTR-9824732 https://reactome.org/PathwayBrowser/#/R-XTR-9824732 G or G analog binds C-ter TLR7 dimer IEA Xenopus tropicalis 17179 R-BTA-176604 https://reactome.org/PathwayBrowser/#/R-BTA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Bos taurus 17179 R-DME-176604 https://reactome.org/PathwayBrowser/#/R-DME-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Drosophila melanogaster 17179 R-DRE-176604 https://reactome.org/PathwayBrowser/#/R-DRE-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Danio rerio 17179 R-GGA-176604 https://reactome.org/PathwayBrowser/#/R-GGA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Gallus gallus 17179 R-HSA-176604 https://reactome.org/PathwayBrowser/#/R-HSA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP TAS Homo sapiens 17179 R-MMU-176604 https://reactome.org/PathwayBrowser/#/R-MMU-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Mus musculus 17179 R-RNO-176604 https://reactome.org/PathwayBrowser/#/R-RNO-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Rattus norvegicus 17179 R-SSC-176604 https://reactome.org/PathwayBrowser/#/R-SSC-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Sus scrofa 17179 R-XTR-176604 https://reactome.org/PathwayBrowser/#/R-XTR-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Xenopus tropicalis 17189 R-BTA-5229273 https://reactome.org/PathwayBrowser/#/R-BTA-5229273 LCN2:2,5DHBA binds Fe3+ IEA Bos taurus 17189 R-BTA-5671707 https://reactome.org/PathwayBrowser/#/R-BTA-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Bos taurus 17189 R-CFA-5229273 https://reactome.org/PathwayBrowser/#/R-CFA-5229273 LCN2:2,5DHBA binds Fe3+ IEA Canis familiaris 17189 R-CFA-5671707 https://reactome.org/PathwayBrowser/#/R-CFA-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Canis familiaris 17189 R-DME-5229273 https://reactome.org/PathwayBrowser/#/R-DME-5229273 LCN2:2,5DHBA binds Fe3+ IEA Drosophila melanogaster 17189 R-DME-5671707 https://reactome.org/PathwayBrowser/#/R-DME-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Drosophila melanogaster 17189 R-DRE-5229273 https://reactome.org/PathwayBrowser/#/R-DRE-5229273 LCN2:2,5DHBA binds Fe3+ IEA Danio rerio 17189 R-GGA-5229273 https://reactome.org/PathwayBrowser/#/R-GGA-5229273 LCN2:2,5DHBA binds Fe3+ IEA Gallus gallus 17189 R-HSA-5229273 https://reactome.org/PathwayBrowser/#/R-HSA-5229273 LCN2:2,5DHBA binds Fe3+ TAS Homo sapiens 17189 R-HSA-5246444 https://reactome.org/PathwayBrowser/#/R-HSA-5246444 SLC22A17 binds LCN2:2,5DHBA:Fe3+ IEA Homo sapiens 17189 R-HSA-5671707 https://reactome.org/PathwayBrowser/#/R-HSA-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA TAS Homo sapiens 17189 R-MMU-5229273 https://reactome.org/PathwayBrowser/#/R-MMU-5229273 LCN2:2,5DHBA binds Fe3+ IEA Mus musculus 17189 R-MMU-5246466 https://reactome.org/PathwayBrowser/#/R-MMU-5246466 Slc22a17 binds Lcn2, internalising it, releasing Fe3+ TAS Mus musculus 17189 R-MMU-5671707 https://reactome.org/PathwayBrowser/#/R-MMU-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Mus musculus 17189 R-RNO-5229273 https://reactome.org/PathwayBrowser/#/R-RNO-5229273 LCN2:2,5DHBA binds Fe3+ IEA Rattus norvegicus 17189 R-RNO-5671707 https://reactome.org/PathwayBrowser/#/R-RNO-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Rattus norvegicus 17189 R-SSC-5229273 https://reactome.org/PathwayBrowser/#/R-SSC-5229273 LCN2:2,5DHBA binds Fe3+ IEA Sus scrofa 17189 R-SSC-5671707 https://reactome.org/PathwayBrowser/#/R-SSC-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Sus scrofa 17189 R-XTR-5229273 https://reactome.org/PathwayBrowser/#/R-XTR-5229273 LCN2:2,5DHBA binds Fe3+ IEA Xenopus tropicalis 171895 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 171895 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 171895 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 171895 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 171895 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 171895 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 171895 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 171895 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 171895 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 17202 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 17202 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 17202 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 17202 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 17202 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 17202 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 17202 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 17211 R-BTA-9717830 https://reactome.org/PathwayBrowser/#/R-BTA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Bos taurus 17211 R-BTA-9717834 https://reactome.org/PathwayBrowser/#/R-BTA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Bos taurus 17211 R-CEL-191303 https://reactome.org/PathwayBrowser/#/R-CEL-191303 FDPS dimer transfers IPPP to GPP IEA Caenorhabditis elegans 17211 R-CEL-191322 https://reactome.org/PathwayBrowser/#/R-CEL-191322 FDPS dimer transfers IPPP to DMAPP IEA Caenorhabditis elegans 17211 R-CFA-191303 https://reactome.org/PathwayBrowser/#/R-CFA-191303 FDPS dimer transfers IPPP to GPP IEA Canis familiaris 17211 R-CFA-191322 https://reactome.org/PathwayBrowser/#/R-CFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Canis familiaris 17211 R-CFA-9717830 https://reactome.org/PathwayBrowser/#/R-CFA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Canis familiaris 17211 R-CFA-9717834 https://reactome.org/PathwayBrowser/#/R-CFA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Canis familiaris 17211 R-DDI-191303 https://reactome.org/PathwayBrowser/#/R-DDI-191303 FDPS dimer transfers IPPP to GPP IEA Dictyostelium discoideum 17211 R-DDI-191322 https://reactome.org/PathwayBrowser/#/R-DDI-191322 FDPS dimer transfers IPPP to DMAPP IEA Dictyostelium discoideum 17211 R-DDI-9717830 https://reactome.org/PathwayBrowser/#/R-DDI-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Dictyostelium discoideum 17211 R-DDI-9717834 https://reactome.org/PathwayBrowser/#/R-DDI-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Dictyostelium discoideum 17211 R-DME-191303 https://reactome.org/PathwayBrowser/#/R-DME-191303 FDPS dimer transfers IPPP to GPP IEA Drosophila melanogaster 17211 R-DME-191322 https://reactome.org/PathwayBrowser/#/R-DME-191322 FDPS dimer transfers IPPP to DMAPP IEA Drosophila melanogaster 17211 R-DME-9717830 https://reactome.org/PathwayBrowser/#/R-DME-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Drosophila melanogaster 17211 R-DME-9717834 https://reactome.org/PathwayBrowser/#/R-DME-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Drosophila melanogaster 17211 R-DRE-191303 https://reactome.org/PathwayBrowser/#/R-DRE-191303 FDPS dimer transfers IPPP to GPP IEA Danio rerio 17211 R-DRE-191322 https://reactome.org/PathwayBrowser/#/R-DRE-191322 FDPS dimer transfers IPPP to DMAPP IEA Danio rerio 17211 R-GGA-191303 https://reactome.org/PathwayBrowser/#/R-GGA-191303 FDPS dimer transfers IPPP to GPP IEA Gallus gallus 17211 R-GGA-191322 https://reactome.org/PathwayBrowser/#/R-GGA-191322 FDPS dimer transfers IPPP to DMAPP IEA Gallus gallus 17211 R-GGA-9717830 https://reactome.org/PathwayBrowser/#/R-GGA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Gallus gallus 17211 R-GGA-9717834 https://reactome.org/PathwayBrowser/#/R-GGA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Gallus gallus 17211 R-HSA-191303 https://reactome.org/PathwayBrowser/#/R-HSA-191303 FDPS dimer transfers IPPP to GPP TAS Homo sapiens 17211 R-HSA-191322 https://reactome.org/PathwayBrowser/#/R-HSA-191322 FDPS dimer transfers IPPP to DMAPP TAS Homo sapiens 17211 R-HSA-9717830 https://reactome.org/PathwayBrowser/#/R-HSA-9717830 GGPS1 hexamer transfers IPPP to GPP TAS Homo sapiens 17211 R-HSA-9717834 https://reactome.org/PathwayBrowser/#/R-HSA-9717834 GGPS1 hexamer transfers IPPP to DMAPP TAS Homo sapiens 17211 R-MMU-191303 https://reactome.org/PathwayBrowser/#/R-MMU-191303 FDPS dimer transfers IPPP to GPP IEA Mus musculus 17211 R-MMU-191322 https://reactome.org/PathwayBrowser/#/R-MMU-191322 FDPS dimer transfers IPPP to DMAPP IEA Mus musculus 17211 R-MMU-9717830 https://reactome.org/PathwayBrowser/#/R-MMU-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Mus musculus 17211 R-MMU-9717834 https://reactome.org/PathwayBrowser/#/R-MMU-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Mus musculus 17211 R-PFA-191303 https://reactome.org/PathwayBrowser/#/R-PFA-191303 FDPS dimer transfers IPPP to GPP IEA Plasmodium falciparum 17211 R-PFA-191322 https://reactome.org/PathwayBrowser/#/R-PFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Plasmodium falciparum 17211 R-RNO-191303 https://reactome.org/PathwayBrowser/#/R-RNO-191303 FDPS dimer transfers IPPP to GPP IEA Rattus norvegicus 17211 R-RNO-191322 https://reactome.org/PathwayBrowser/#/R-RNO-191322 FDPS dimer transfers IPPP to DMAPP IEA Rattus norvegicus 17211 R-RNO-9717830 https://reactome.org/PathwayBrowser/#/R-RNO-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Rattus norvegicus 17211 R-RNO-9717834 https://reactome.org/PathwayBrowser/#/R-RNO-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Rattus norvegicus 17211 R-SCE-191303 https://reactome.org/PathwayBrowser/#/R-SCE-191303 FDPS dimer transfers IPPP to GPP IEA Saccharomyces cerevisiae 17211 R-SCE-191322 https://reactome.org/PathwayBrowser/#/R-SCE-191322 FDPS dimer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 17211 R-SCE-9717830 https://reactome.org/PathwayBrowser/#/R-SCE-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Saccharomyces cerevisiae 17211 R-SCE-9717834 https://reactome.org/PathwayBrowser/#/R-SCE-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 17211 R-SPO-191303 https://reactome.org/PathwayBrowser/#/R-SPO-191303 FDPS dimer transfers IPPP to GPP IEA Schizosaccharomyces pombe 17211 R-SPO-191322 https://reactome.org/PathwayBrowser/#/R-SPO-191322 FDPS dimer transfers IPPP to DMAPP IEA Schizosaccharomyces pombe 17211 R-SSC-191303 https://reactome.org/PathwayBrowser/#/R-SSC-191303 FDPS dimer transfers IPPP to GPP IEA Sus scrofa 17211 R-SSC-191322 https://reactome.org/PathwayBrowser/#/R-SSC-191322 FDPS dimer transfers IPPP to DMAPP IEA Sus scrofa 17211 R-SSC-9717830 https://reactome.org/PathwayBrowser/#/R-SSC-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Sus scrofa 17211 R-SSC-9717834 https://reactome.org/PathwayBrowser/#/R-SSC-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Sus scrofa 17211 R-XTR-9717830 https://reactome.org/PathwayBrowser/#/R-XTR-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Xenopus tropicalis 17211 R-XTR-9717834 https://reactome.org/PathwayBrowser/#/R-XTR-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Xenopus tropicalis 17240 R-BTA-70994 https://reactome.org/PathwayBrowser/#/R-BTA-70994 SDH complex dehydrogenates succinate IEA Bos taurus 17240 R-CEL-70994 https://reactome.org/PathwayBrowser/#/R-CEL-70994 SDH complex dehydrogenates succinate IEA Caenorhabditis elegans 17240 R-CFA-70994 https://reactome.org/PathwayBrowser/#/R-CFA-70994 SDH complex dehydrogenates succinate IEA Canis familiaris 17240 R-DDI-70994 https://reactome.org/PathwayBrowser/#/R-DDI-70994 SDH complex dehydrogenates succinate IEA Dictyostelium discoideum 17240 R-DME-70994 https://reactome.org/PathwayBrowser/#/R-DME-70994 SDH complex dehydrogenates succinate IEA Drosophila melanogaster 17240 R-DRE-70994 https://reactome.org/PathwayBrowser/#/R-DRE-70994 SDH complex dehydrogenates succinate IEA Danio rerio 17240 R-GGA-70994 https://reactome.org/PathwayBrowser/#/R-GGA-70994 SDH complex dehydrogenates succinate IEA Gallus gallus 17240 R-HSA-70994 https://reactome.org/PathwayBrowser/#/R-HSA-70994 SDH complex dehydrogenates succinate TAS Homo sapiens 17240 R-MMU-70994 https://reactome.org/PathwayBrowser/#/R-MMU-70994 SDH complex dehydrogenates succinate IEA Mus musculus 17240 R-RNO-70994 https://reactome.org/PathwayBrowser/#/R-RNO-70994 SDH complex dehydrogenates succinate IEA Rattus norvegicus 17240 R-SCE-70994 https://reactome.org/PathwayBrowser/#/R-SCE-70994 SDH complex dehydrogenates succinate IEA Saccharomyces cerevisiae 17240 R-SPO-70994 https://reactome.org/PathwayBrowser/#/R-SPO-70994 SDH complex dehydrogenates succinate IEA Schizosaccharomyces pombe 17240 R-SSC-70994 https://reactome.org/PathwayBrowser/#/R-SSC-70994 SDH complex dehydrogenates succinate IEA Sus scrofa 17240 R-XTR-70994 https://reactome.org/PathwayBrowser/#/R-XTR-70994 SDH complex dehydrogenates succinate IEA Xenopus tropicalis 17245 R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 17245 R-BTA-189398 https://reactome.org/PathwayBrowser/#/R-BTA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Bos taurus 17245 R-BTA-8953398 https://reactome.org/PathwayBrowser/#/R-BTA-8953398 PIR oxygenates quercetin IEA Bos taurus 17245 R-BTA-9707504 https://reactome.org/PathwayBrowser/#/R-BTA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Bos taurus 17245 R-BTA-9709317 https://reactome.org/PathwayBrowser/#/R-BTA-9709317 CO binds to free ferrohemoglobin IEA Bos taurus 17245 R-BTA-9709406 https://reactome.org/PathwayBrowser/#/R-BTA-9709406 CO binds to Cytochrome c oxidase IEA Bos taurus 17245 R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 17245 R-CFA-189398 https://reactome.org/PathwayBrowser/#/R-CFA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Canis familiaris 17245 R-CFA-8953398 https://reactome.org/PathwayBrowser/#/R-CFA-8953398 PIR oxygenates quercetin IEA Canis familiaris 17245 R-CFA-9707504 https://reactome.org/PathwayBrowser/#/R-CFA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Canis familiaris 17245 R-CFA-9709317 https://reactome.org/PathwayBrowser/#/R-CFA-9709317 CO binds to free ferrohemoglobin IEA Canis familiaris 17245 R-CFA-9709406 https://reactome.org/PathwayBrowser/#/R-CFA-9709406 CO binds to Cytochrome c oxidase IEA Canis familiaris 17245 R-DDI-8953398 https://reactome.org/PathwayBrowser/#/R-DDI-8953398 PIR oxygenates quercetin IEA Dictyostelium discoideum 17245 R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 17245 R-DME-189398 https://reactome.org/PathwayBrowser/#/R-DME-189398 HMOX1 dimer, HMOX2 cleave heme IEA Drosophila melanogaster 17245 R-DME-9709406 https://reactome.org/PathwayBrowser/#/R-DME-9709406 CO binds to Cytochrome c oxidase IEA Drosophila melanogaster 17245 R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 17245 R-DRE-189398 https://reactome.org/PathwayBrowser/#/R-DRE-189398 HMOX1 dimer, HMOX2 cleave heme IEA Danio rerio 17245 R-DRE-9707504 https://reactome.org/PathwayBrowser/#/R-DRE-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Danio rerio 17245 R-DRE-9709317 https://reactome.org/PathwayBrowser/#/R-DRE-9709317 CO binds to free ferrohemoglobin IEA Danio rerio 17245 R-DRE-9709406 https://reactome.org/PathwayBrowser/#/R-DRE-9709406 CO binds to Cytochrome c oxidase IEA Danio rerio 17245 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 17245 R-GGA-189398 https://reactome.org/PathwayBrowser/#/R-GGA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Gallus gallus 17245 R-GGA-9707504 https://reactome.org/PathwayBrowser/#/R-GGA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Gallus gallus 17245 R-GGA-9709317 https://reactome.org/PathwayBrowser/#/R-GGA-9709317 CO binds to free ferrohemoglobin IEA Gallus gallus 17245 R-GGA-9709406 https://reactome.org/PathwayBrowser/#/R-GGA-9709406 CO binds to Cytochrome c oxidase IEA Gallus gallus 17245 R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 17245 R-HSA-189398 https://reactome.org/PathwayBrowser/#/R-HSA-189398 HMOX1 dimer, HMOX2 cleave heme TAS Homo sapiens 17245 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 17245 R-HSA-8953398 https://reactome.org/PathwayBrowser/#/R-HSA-8953398 PIR oxygenates quercetin TAS Homo sapiens 17245 R-HSA-9707504 https://reactome.org/PathwayBrowser/#/R-HSA-9707504 H2O2 oxidises ferrohemoglobin to MetHb TAS Homo sapiens 17245 R-HSA-9709317 https://reactome.org/PathwayBrowser/#/R-HSA-9709317 CO binds to free ferrohemoglobin TAS Homo sapiens 17245 R-HSA-9709366 https://reactome.org/PathwayBrowser/#/R-HSA-9709366 CO translocates from cytosol to mitochondrial inner membrane TAS Homo sapiens 17245 R-HSA-9709396 https://reactome.org/PathwayBrowser/#/R-HSA-9709396 CO translocates from cytosol to extracellular region TAS Homo sapiens 17245 R-HSA-9709406 https://reactome.org/PathwayBrowser/#/R-HSA-9709406 CO binds to Cytochrome c oxidase TAS Homo sapiens 17245 R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 17245 R-MMU-189398 https://reactome.org/PathwayBrowser/#/R-MMU-189398 HMOX1 dimer, HMOX2 cleave heme IEA Mus musculus 17245 R-MMU-8953398 https://reactome.org/PathwayBrowser/#/R-MMU-8953398 PIR oxygenates quercetin IEA Mus musculus 17245 R-MMU-9707504 https://reactome.org/PathwayBrowser/#/R-MMU-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Mus musculus 17245 R-MMU-9709317 https://reactome.org/PathwayBrowser/#/R-MMU-9709317 CO binds to free ferrohemoglobin IEA Mus musculus 17245 R-MMU-9709406 https://reactome.org/PathwayBrowser/#/R-MMU-9709406 CO binds to Cytochrome c oxidase IEA Mus musculus 17245 R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 17245 R-RNO-189398 https://reactome.org/PathwayBrowser/#/R-RNO-189398 HMOX1 dimer, HMOX2 cleave heme IEA Rattus norvegicus 17245 R-RNO-8953398 https://reactome.org/PathwayBrowser/#/R-RNO-8953398 PIR oxygenates quercetin IEA Rattus norvegicus 17245 R-RNO-9707504 https://reactome.org/PathwayBrowser/#/R-RNO-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Rattus norvegicus 17245 R-RNO-9709317 https://reactome.org/PathwayBrowser/#/R-RNO-9709317 CO binds to free ferrohemoglobin IEA Rattus norvegicus 17245 R-RNO-9709406 https://reactome.org/PathwayBrowser/#/R-RNO-9709406 CO binds to Cytochrome c oxidase IEA Rattus norvegicus 17245 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa 17245 R-SSC-189398 https://reactome.org/PathwayBrowser/#/R-SSC-189398 HMOX1 dimer, HMOX2 cleave heme IEA Sus scrofa 17245 R-SSC-8953398 https://reactome.org/PathwayBrowser/#/R-SSC-8953398 PIR oxygenates quercetin IEA Sus scrofa 17245 R-SSC-9707504 https://reactome.org/PathwayBrowser/#/R-SSC-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Sus scrofa 17245 R-SSC-9709317 https://reactome.org/PathwayBrowser/#/R-SSC-9709317 CO binds to free ferrohemoglobin IEA Sus scrofa 17245 R-SSC-9709406 https://reactome.org/PathwayBrowser/#/R-SSC-9709406 CO binds to Cytochrome c oxidase IEA Sus scrofa 17245 R-XTR-163214 https://reactome.org/PathwayBrowser/#/R-XTR-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Xenopus tropicalis 17245 R-XTR-189398 https://reactome.org/PathwayBrowser/#/R-XTR-189398 HMOX1 dimer, HMOX2 cleave heme IEA Xenopus tropicalis 17245 R-XTR-8953398 https://reactome.org/PathwayBrowser/#/R-XTR-8953398 PIR oxygenates quercetin IEA Xenopus tropicalis 17245 R-XTR-9707504 https://reactome.org/PathwayBrowser/#/R-XTR-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Xenopus tropicalis 17245 R-XTR-9709317 https://reactome.org/PathwayBrowser/#/R-XTR-9709317 CO binds to free ferrohemoglobin IEA Xenopus tropicalis 17245 R-XTR-9709406 https://reactome.org/PathwayBrowser/#/R-XTR-9709406 CO binds to Cytochrome c oxidase IEA Xenopus tropicalis 17252 R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 17252 R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 17252 R-BTA-193961 https://reactome.org/PathwayBrowser/#/R-BTA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Bos taurus 17252 R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 17252 R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 17252 R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 17252 R-CFA-193961 https://reactome.org/PathwayBrowser/#/R-CFA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Canis familiaris 17252 R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 17252 R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 17252 R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 17252 R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 17252 R-DRE-193961 https://reactome.org/PathwayBrowser/#/R-DRE-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Danio rerio 17252 R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 17252 R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 17252 R-GGA-193961 https://reactome.org/PathwayBrowser/#/R-GGA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Gallus gallus 17252 R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 17252 R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 17252 R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 17252 R-HSA-193961 https://reactome.org/PathwayBrowser/#/R-HSA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone TAS Homo sapiens 17252 R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 17252 R-HSA-9035956 https://reactome.org/PathwayBrowser/#/R-HSA-9035956 Defective CYP17A1 does not cleave 17aHPROG TAS Homo sapiens 17252 R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 17252 R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 17252 R-MMU-193961 https://reactome.org/PathwayBrowser/#/R-MMU-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Mus musculus 17252 R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 17252 R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 17252 R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 17252 R-RNO-193961 https://reactome.org/PathwayBrowser/#/R-RNO-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Rattus norvegicus 17252 R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 17252 R-SSC-193072 https://reactome.org/PathwayBrowser/#/R-SSC-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Sus scrofa 17252 R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 17252 R-SSC-193961 https://reactome.org/PathwayBrowser/#/R-SSC-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Sus scrofa 17252 R-SSC-193981 https://reactome.org/PathwayBrowser/#/R-SSC-193981 CYP21A2 oxidises 17HPROG IEA Sus scrofa 17252 R-XTR-193072 https://reactome.org/PathwayBrowser/#/R-XTR-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Xenopus tropicalis 17252 R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 17256 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 17256 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 17256 R-BTA-109530 https://reactome.org/PathwayBrowser/#/R-BTA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Bos taurus 17256 R-BTA-109624 https://reactome.org/PathwayBrowser/#/R-BTA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Bos taurus 17256 R-BTA-109671 https://reactome.org/PathwayBrowser/#/R-BTA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Bos taurus 17256 R-BTA-74207 https://reactome.org/PathwayBrowser/#/R-BTA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Bos taurus 17256 R-BTA-74241 https://reactome.org/PathwayBrowser/#/R-BTA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Bos taurus 17256 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans 17256 R-CEL-109624 https://reactome.org/PathwayBrowser/#/R-CEL-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Caenorhabditis elegans 17256 R-CEL-74241 https://reactome.org/PathwayBrowser/#/R-CEL-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Caenorhabditis elegans 17256 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 17256 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 17256 R-CFA-109624 https://reactome.org/PathwayBrowser/#/R-CFA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Canis familiaris 17256 R-CFA-109671 https://reactome.org/PathwayBrowser/#/R-CFA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Canis familiaris 17256 R-CFA-74207 https://reactome.org/PathwayBrowser/#/R-CFA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Canis familiaris 17256 R-CFA-74241 https://reactome.org/PathwayBrowser/#/R-CFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Canis familiaris 17256 R-DDI-109624 https://reactome.org/PathwayBrowser/#/R-DDI-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Dictyostelium discoideum 17256 R-DDI-74241 https://reactome.org/PathwayBrowser/#/R-DDI-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Dictyostelium discoideum 17256 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 17256 R-DME-109530 https://reactome.org/PathwayBrowser/#/R-DME-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Drosophila melanogaster 17256 R-DME-109624 https://reactome.org/PathwayBrowser/#/R-DME-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Drosophila melanogaster 17256 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 17256 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 17256 R-DRE-109624 https://reactome.org/PathwayBrowser/#/R-DRE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Danio rerio 17256 R-DRE-109671 https://reactome.org/PathwayBrowser/#/R-DRE-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Danio rerio 17256 R-DRE-74207 https://reactome.org/PathwayBrowser/#/R-DRE-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Danio rerio 17256 R-DRE-74241 https://reactome.org/PathwayBrowser/#/R-DRE-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Danio rerio 17256 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 17256 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 17256 R-GGA-109624 https://reactome.org/PathwayBrowser/#/R-GGA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Gallus gallus 17256 R-GGA-109671 https://reactome.org/PathwayBrowser/#/R-GGA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Gallus gallus 17256 R-GGA-74241 https://reactome.org/PathwayBrowser/#/R-GGA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Gallus gallus 17256 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 17256 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 17256 R-HSA-109530 https://reactome.org/PathwayBrowser/#/R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 TAS Homo sapiens 17256 R-HSA-109624 https://reactome.org/PathwayBrowser/#/R-HSA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) TAS Homo sapiens 17256 R-HSA-109671 https://reactome.org/PathwayBrowser/#/R-HSA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) TAS Homo sapiens 17256 R-HSA-6789114 https://reactome.org/PathwayBrowser/#/R-HSA-6789114 Hydroxyl radical reacts with the base and sugar moiety of DNA TAS Homo sapiens 17256 R-HSA-74207 https://reactome.org/PathwayBrowser/#/R-HSA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) TAS Homo sapiens 17256 R-HSA-74241 https://reactome.org/PathwayBrowser/#/R-HSA-74241 ADA catalyzes the deamination of (deoxy)adenosine TAS Homo sapiens 17256 R-HSA-9734745 https://reactome.org/PathwayBrowser/#/R-HSA-9734745 Defective ADA does not deaminate (deoxy)adenosine TAS Homo sapiens 17256 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 17256 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 17256 R-MMU-109530 https://reactome.org/PathwayBrowser/#/R-MMU-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Mus musculus 17256 R-MMU-109624 https://reactome.org/PathwayBrowser/#/R-MMU-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Mus musculus 17256 R-MMU-109671 https://reactome.org/PathwayBrowser/#/R-MMU-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Mus musculus 17256 R-MMU-74207 https://reactome.org/PathwayBrowser/#/R-MMU-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Mus musculus 17256 R-MMU-74241 https://reactome.org/PathwayBrowser/#/R-MMU-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Mus musculus 17256 R-PFA-74241 https://reactome.org/PathwayBrowser/#/R-PFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Plasmodium falciparum 17256 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 17256 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 17256 R-RNO-109530 https://reactome.org/PathwayBrowser/#/R-RNO-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Rattus norvegicus 17256 R-RNO-109624 https://reactome.org/PathwayBrowser/#/R-RNO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Rattus norvegicus 17256 R-RNO-109671 https://reactome.org/PathwayBrowser/#/R-RNO-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Rattus norvegicus 17256 R-RNO-74207 https://reactome.org/PathwayBrowser/#/R-RNO-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Rattus norvegicus 17256 R-RNO-74241 https://reactome.org/PathwayBrowser/#/R-RNO-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Rattus norvegicus 17256 R-SCE-109624 https://reactome.org/PathwayBrowser/#/R-SCE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Saccharomyces cerevisiae 17256 R-SPO-109624 https://reactome.org/PathwayBrowser/#/R-SPO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Schizosaccharomyces pombe 17256 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 17256 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 17256 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa 17256 R-SSC-109624 https://reactome.org/PathwayBrowser/#/R-SSC-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Sus scrofa 17256 R-SSC-74207 https://reactome.org/PathwayBrowser/#/R-SSC-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Sus scrofa 17256 R-SSC-74241 https://reactome.org/PathwayBrowser/#/R-SSC-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Sus scrofa 17256 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 17256 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 17256 R-XTR-109530 https://reactome.org/PathwayBrowser/#/R-XTR-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Xenopus tropicalis 17256 R-XTR-109624 https://reactome.org/PathwayBrowser/#/R-XTR-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Xenopus tropicalis 17256 R-XTR-109671 https://reactome.org/PathwayBrowser/#/R-XTR-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Xenopus tropicalis 17256 R-XTR-74207 https://reactome.org/PathwayBrowser/#/R-XTR-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Xenopus tropicalis 17256 R-XTR-74241 https://reactome.org/PathwayBrowser/#/R-XTR-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Xenopus tropicalis 17263 R-BTA-176664 https://reactome.org/PathwayBrowser/#/R-BTA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Bos taurus 17263 R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 17263 R-BTA-5693390 https://reactome.org/PathwayBrowser/#/R-BTA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Bos taurus 17263 R-BTA-5696822 https://reactome.org/PathwayBrowser/#/R-BTA-5696822 AKR1B15 reduces EST17b to E1 IEA Bos taurus 17263 R-BTA-6810594 https://reactome.org/PathwayBrowser/#/R-BTA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 17263 R-BTA-804969 https://reactome.org/PathwayBrowser/#/R-BTA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Bos taurus 17263 R-BTA-8862137 https://reactome.org/PathwayBrowser/#/R-BTA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 17263 R-BTA-9008258 https://reactome.org/PathwayBrowser/#/R-BTA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Bos taurus 17263 R-BTA-9008270 https://reactome.org/PathwayBrowser/#/R-BTA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Bos taurus 17263 R-BTA-9008271 https://reactome.org/PathwayBrowser/#/R-BTA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Bos taurus 17263 R-BTA-9008285 https://reactome.org/PathwayBrowser/#/R-BTA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Bos taurus 17263 R-BTA-9009526 https://reactome.org/PathwayBrowser/#/R-BTA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 17263 R-BTA-9009533 https://reactome.org/PathwayBrowser/#/R-BTA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Bos taurus 17263 R-BTA-9009536 https://reactome.org/PathwayBrowser/#/R-BTA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Bos taurus 17263 R-BTA-9009541 https://reactome.org/PathwayBrowser/#/R-BTA-9009541 ESR1 binds to TFF1 gene promoter IEA Bos taurus 17263 R-BTA-9023860 https://reactome.org/PathwayBrowser/#/R-BTA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Bos taurus 17263 R-BTA-9023861 https://reactome.org/PathwayBrowser/#/R-BTA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 17263 R-BTA-9023884 https://reactome.org/PathwayBrowser/#/R-BTA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Bos taurus 17263 R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 17263 R-CEL-5696822 https://reactome.org/PathwayBrowser/#/R-CEL-5696822 AKR1B15 reduces EST17b to E1 IEA Caenorhabditis elegans 17263 R-CFA-176664 https://reactome.org/PathwayBrowser/#/R-CFA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Canis familiaris 17263 R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 17263 R-CFA-5693390 https://reactome.org/PathwayBrowser/#/R-CFA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Canis familiaris 17263 R-CFA-804969 https://reactome.org/PathwayBrowser/#/R-CFA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Canis familiaris 17263 R-CFA-8862137 https://reactome.org/PathwayBrowser/#/R-CFA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Canis familiaris 17263 R-CFA-9008258 https://reactome.org/PathwayBrowser/#/R-CFA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Canis familiaris 17263 R-CFA-9008270 https://reactome.org/PathwayBrowser/#/R-CFA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Canis familiaris 17263 R-CFA-9008271 https://reactome.org/PathwayBrowser/#/R-CFA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Canis familiaris 17263 R-CFA-9008285 https://reactome.org/PathwayBrowser/#/R-CFA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Canis familiaris 17263 R-CFA-9009526 https://reactome.org/PathwayBrowser/#/R-CFA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 17263 R-CFA-9009533 https://reactome.org/PathwayBrowser/#/R-CFA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Canis familiaris 17263 R-CFA-9009536 https://reactome.org/PathwayBrowser/#/R-CFA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Canis familiaris 17263 R-CFA-9009541 https://reactome.org/PathwayBrowser/#/R-CFA-9009541 ESR1 binds to TFF1 gene promoter IEA Canis familiaris 17263 R-CFA-9023860 https://reactome.org/PathwayBrowser/#/R-CFA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Canis familiaris 17263 R-CFA-9023861 https://reactome.org/PathwayBrowser/#/R-CFA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 17263 R-CFA-9023884 https://reactome.org/PathwayBrowser/#/R-CFA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Canis familiaris 17263 R-DDI-5696822 https://reactome.org/PathwayBrowser/#/R-DDI-5696822 AKR1B15 reduces EST17b to E1 IEA Dictyostelium discoideum 17263 R-DDI-804969 https://reactome.org/PathwayBrowser/#/R-DDI-804969 HSD17B1 hydrogenates E1 to EST17b IEA Dictyostelium discoideum 17263 R-DDI-9023860 https://reactome.org/PathwayBrowser/#/R-DDI-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Dictyostelium discoideum 17263 R-DME-176664 https://reactome.org/PathwayBrowser/#/R-DME-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Drosophila melanogaster 17263 R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 17263 R-DME-5693390 https://reactome.org/PathwayBrowser/#/R-DME-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Drosophila melanogaster 17263 R-DME-5696822 https://reactome.org/PathwayBrowser/#/R-DME-5696822 AKR1B15 reduces EST17b to E1 IEA Drosophila melanogaster 17263 R-DME-8862137 https://reactome.org/PathwayBrowser/#/R-DME-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Drosophila melanogaster 17263 R-DME-9008258 https://reactome.org/PathwayBrowser/#/R-DME-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Drosophila melanogaster 17263 R-DME-9008270 https://reactome.org/PathwayBrowser/#/R-DME-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Drosophila melanogaster 17263 R-DME-9008285 https://reactome.org/PathwayBrowser/#/R-DME-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Drosophila melanogaster 17263 R-DME-9009526 https://reactome.org/PathwayBrowser/#/R-DME-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 17263 R-DME-9009533 https://reactome.org/PathwayBrowser/#/R-DME-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Drosophila melanogaster 17263 R-DME-9009536 https://reactome.org/PathwayBrowser/#/R-DME-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Drosophila melanogaster 17263 R-DME-9009541 https://reactome.org/PathwayBrowser/#/R-DME-9009541 ESR1 binds to TFF1 gene promoter IEA Drosophila melanogaster 17263 R-DME-9023860 https://reactome.org/PathwayBrowser/#/R-DME-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Drosophila melanogaster 17263 R-DME-9023861 https://reactome.org/PathwayBrowser/#/R-DME-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 17263 R-DME-9023884 https://reactome.org/PathwayBrowser/#/R-DME-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Drosophila melanogaster 17263 R-DRE-176664 https://reactome.org/PathwayBrowser/#/R-DRE-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Danio rerio 17263 R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 17263 R-DRE-5696822 https://reactome.org/PathwayBrowser/#/R-DRE-5696822 AKR1B15 reduces EST17b to E1 IEA Danio rerio 17263 R-DRE-6810594 https://reactome.org/PathwayBrowser/#/R-DRE-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Danio rerio 17263 R-DRE-9009526 https://reactome.org/PathwayBrowser/#/R-DRE-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Danio rerio 17263 R-DRE-9009533 https://reactome.org/PathwayBrowser/#/R-DRE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Danio rerio 17263 R-DRE-9009541 https://reactome.org/PathwayBrowser/#/R-DRE-9009541 ESR1 binds to TFF1 gene promoter IEA Danio rerio 17263 R-DRE-9023860 https://reactome.org/PathwayBrowser/#/R-DRE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Danio rerio 17263 R-GGA-176664 https://reactome.org/PathwayBrowser/#/R-GGA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Gallus gallus 17263 R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 17263 R-GGA-5693390 https://reactome.org/PathwayBrowser/#/R-GGA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Gallus gallus 17263 R-GGA-5696822 https://reactome.org/PathwayBrowser/#/R-GGA-5696822 AKR1B15 reduces EST17b to E1 IEA Gallus gallus 17263 R-GGA-8862137 https://reactome.org/PathwayBrowser/#/R-GGA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Gallus gallus 17263 R-GGA-9008258 https://reactome.org/PathwayBrowser/#/R-GGA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Gallus gallus 17263 R-GGA-9008270 https://reactome.org/PathwayBrowser/#/R-GGA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Gallus gallus 17263 R-GGA-9008285 https://reactome.org/PathwayBrowser/#/R-GGA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Gallus gallus 17263 R-GGA-9009533 https://reactome.org/PathwayBrowser/#/R-GGA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Gallus gallus 17263 R-GGA-9009536 https://reactome.org/PathwayBrowser/#/R-GGA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Gallus gallus 17263 R-GGA-9009541 https://reactome.org/PathwayBrowser/#/R-GGA-9009541 ESR1 binds to TFF1 gene promoter IEA Gallus gallus 17263 R-GGA-9023860 https://reactome.org/PathwayBrowser/#/R-GGA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Gallus gallus 17263 R-GGA-9023884 https://reactome.org/PathwayBrowser/#/R-GGA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Gallus gallus 17263 R-HSA-176664 https://reactome.org/PathwayBrowser/#/R-HSA-176664 estrone + PAPS => estrone 3-sulfate + PAP TAS Homo sapiens 17263 R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 17263 R-HSA-5693390 https://reactome.org/PathwayBrowser/#/R-HSA-5693390 HSD17B11 dehydrogenates EST17b to E1 TAS Homo sapiens 17263 R-HSA-5696822 https://reactome.org/PathwayBrowser/#/R-HSA-5696822 AKR1B15 reduces EST17b to E1 TAS Homo sapiens 17263 R-HSA-6810594 https://reactome.org/PathwayBrowser/#/R-HSA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 17263 R-HSA-804969 https://reactome.org/PathwayBrowser/#/R-HSA-804969 HSD17B1 hydrogenates E1 to EST17b TAS Homo sapiens 17263 R-HSA-8862137 https://reactome.org/PathwayBrowser/#/R-HSA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 17263 R-HSA-9008258 https://reactome.org/PathwayBrowser/#/R-HSA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene TAS Homo sapiens 17263 R-HSA-9008267 https://reactome.org/PathwayBrowser/#/R-HSA-9008267 ESR1 binds to TGFA gene promoter TAS Homo sapiens 17263 R-HSA-9008270 https://reactome.org/PathwayBrowser/#/R-HSA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene TAS Homo sapiens 17263 R-HSA-9008271 https://reactome.org/PathwayBrowser/#/R-HSA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter TAS Homo sapiens 17263 R-HSA-9008285 https://reactome.org/PathwayBrowser/#/R-HSA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 TAS Homo sapiens 17263 R-HSA-9008315 https://reactome.org/PathwayBrowser/#/R-HSA-9008315 TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen TAS Homo sapiens 17263 R-HSA-9009526 https://reactome.org/PathwayBrowser/#/R-HSA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 17263 R-HSA-9009533 https://reactome.org/PathwayBrowser/#/R-HSA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter TAS Homo sapiens 17263 R-HSA-9009536 https://reactome.org/PathwayBrowser/#/R-HSA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter TAS Homo sapiens 17263 R-HSA-9009541 https://reactome.org/PathwayBrowser/#/R-HSA-9009541 ESR1 binds to TFF1 gene promoter TAS Homo sapiens 17263 R-HSA-9023859 https://reactome.org/PathwayBrowser/#/R-HSA-9023859 Estrogen-responsive TFF1 gene expression TAS Homo sapiens 17263 R-HSA-9023860 https://reactome.org/PathwayBrowser/#/R-HSA-9023860 Histone acetyltransferases are recruited to the TFF1 gene TAS Homo sapiens 17263 R-HSA-9023861 https://reactome.org/PathwayBrowser/#/R-HSA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 17263 R-HSA-9023884 https://reactome.org/PathwayBrowser/#/R-HSA-9023884 NCOA1 recruits EP300 to TGFA promoter TAS Homo sapiens 17263 R-MMU-176664 https://reactome.org/PathwayBrowser/#/R-MMU-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Mus musculus 17263 R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 17263 R-MMU-5693390 https://reactome.org/PathwayBrowser/#/R-MMU-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Mus musculus 17263 R-MMU-5696822 https://reactome.org/PathwayBrowser/#/R-MMU-5696822 AKR1B15 reduces EST17b to E1 IEA Mus musculus 17263 R-MMU-6810594 https://reactome.org/PathwayBrowser/#/R-MMU-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 17263 R-MMU-804969 https://reactome.org/PathwayBrowser/#/R-MMU-804969 HSD17B1 hydrogenates E1 to EST17b IEA Mus musculus 17263 R-MMU-8862137 https://reactome.org/PathwayBrowser/#/R-MMU-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 17263 R-MMU-9008258 https://reactome.org/PathwayBrowser/#/R-MMU-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Mus musculus 17263 R-MMU-9008270 https://reactome.org/PathwayBrowser/#/R-MMU-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Mus musculus 17263 R-MMU-9008271 https://reactome.org/PathwayBrowser/#/R-MMU-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Mus musculus 17263 R-MMU-9008285 https://reactome.org/PathwayBrowser/#/R-MMU-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Mus musculus 17263 R-MMU-9009526 https://reactome.org/PathwayBrowser/#/R-MMU-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 17263 R-MMU-9009533 https://reactome.org/PathwayBrowser/#/R-MMU-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Mus musculus 17263 R-MMU-9009536 https://reactome.org/PathwayBrowser/#/R-MMU-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Mus musculus 17263 R-MMU-9009541 https://reactome.org/PathwayBrowser/#/R-MMU-9009541 ESR1 binds to TFF1 gene promoter IEA Mus musculus 17263 R-MMU-9023860 https://reactome.org/PathwayBrowser/#/R-MMU-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Mus musculus 17263 R-MMU-9023861 https://reactome.org/PathwayBrowser/#/R-MMU-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 17263 R-MMU-9023884 https://reactome.org/PathwayBrowser/#/R-MMU-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Mus musculus 17263 R-RNO-176664 https://reactome.org/PathwayBrowser/#/R-RNO-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Rattus norvegicus 17263 R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 17263 R-RNO-5693390 https://reactome.org/PathwayBrowser/#/R-RNO-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Rattus norvegicus 17263 R-RNO-5696822 https://reactome.org/PathwayBrowser/#/R-RNO-5696822 AKR1B15 reduces EST17b to E1 IEA Rattus norvegicus 17263 R-RNO-6810594 https://reactome.org/PathwayBrowser/#/R-RNO-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 17263 R-RNO-804969 https://reactome.org/PathwayBrowser/#/R-RNO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Rattus norvegicus 17263 R-RNO-8862137 https://reactome.org/PathwayBrowser/#/R-RNO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 17263 R-RNO-9008258 https://reactome.org/PathwayBrowser/#/R-RNO-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Rattus norvegicus 17263 R-RNO-9008270 https://reactome.org/PathwayBrowser/#/R-RNO-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Rattus norvegicus 17263 R-RNO-9008271 https://reactome.org/PathwayBrowser/#/R-RNO-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Rattus norvegicus 17263 R-RNO-9008285 https://reactome.org/PathwayBrowser/#/R-RNO-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Rattus norvegicus 17263 R-RNO-9009526 https://reactome.org/PathwayBrowser/#/R-RNO-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 17263 R-RNO-9009533 https://reactome.org/PathwayBrowser/#/R-RNO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Rattus norvegicus 17263 R-RNO-9009536 https://reactome.org/PathwayBrowser/#/R-RNO-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Rattus norvegicus 17263 R-RNO-9009541 https://reactome.org/PathwayBrowser/#/R-RNO-9009541 ESR1 binds to TFF1 gene promoter IEA Rattus norvegicus 17263 R-RNO-9023860 https://reactome.org/PathwayBrowser/#/R-RNO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Rattus norvegicus 17263 R-RNO-9023861 https://reactome.org/PathwayBrowser/#/R-RNO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 17263 R-RNO-9023884 https://reactome.org/PathwayBrowser/#/R-RNO-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Rattus norvegicus 17263 R-SCE-5693390 https://reactome.org/PathwayBrowser/#/R-SCE-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Saccharomyces cerevisiae 17263 R-SCE-5696822 https://reactome.org/PathwayBrowser/#/R-SCE-5696822 AKR1B15 reduces EST17b to E1 IEA Saccharomyces cerevisiae 17263 R-SCE-9009533 https://reactome.org/PathwayBrowser/#/R-SCE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Saccharomyces cerevisiae 17263 R-SCE-9023860 https://reactome.org/PathwayBrowser/#/R-SCE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Saccharomyces cerevisiae 17263 R-SCE-9023861 https://reactome.org/PathwayBrowser/#/R-SCE-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Saccharomyces cerevisiae 17263 R-SPO-5696822 https://reactome.org/PathwayBrowser/#/R-SPO-5696822 AKR1B15 reduces EST17b to E1 IEA Schizosaccharomyces pombe 17263 R-SPO-804969 https://reactome.org/PathwayBrowser/#/R-SPO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Schizosaccharomyces pombe 17263 R-SPO-8862137 https://reactome.org/PathwayBrowser/#/R-SPO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Schizosaccharomyces pombe 17263 R-SPO-9009533 https://reactome.org/PathwayBrowser/#/R-SPO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Schizosaccharomyces pombe 17263 R-SPO-9023860 https://reactome.org/PathwayBrowser/#/R-SPO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Schizosaccharomyces pombe 17263 R-SPO-9023861 https://reactome.org/PathwayBrowser/#/R-SPO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Schizosaccharomyces pombe 17263 R-SSC-176664 https://reactome.org/PathwayBrowser/#/R-SSC-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Sus scrofa 17263 R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 17263 R-SSC-5693390 https://reactome.org/PathwayBrowser/#/R-SSC-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Sus scrofa 17263 R-SSC-804969 https://reactome.org/PathwayBrowser/#/R-SSC-804969 HSD17B1 hydrogenates E1 to EST17b IEA Sus scrofa 17263 R-SSC-8862137 https://reactome.org/PathwayBrowser/#/R-SSC-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Sus scrofa 17263 R-SSC-9008258 https://reactome.org/PathwayBrowser/#/R-SSC-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Sus scrofa 17263 R-SSC-9008270 https://reactome.org/PathwayBrowser/#/R-SSC-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Sus scrofa 17263 R-SSC-9008271 https://reactome.org/PathwayBrowser/#/R-SSC-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Sus scrofa 17263 R-SSC-9008285 https://reactome.org/PathwayBrowser/#/R-SSC-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Sus scrofa 17263 R-SSC-9009526 https://reactome.org/PathwayBrowser/#/R-SSC-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 17263 R-SSC-9009536 https://reactome.org/PathwayBrowser/#/R-SSC-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Sus scrofa 17263 R-SSC-9009541 https://reactome.org/PathwayBrowser/#/R-SSC-9009541 ESR1 binds to TFF1 gene promoter IEA Sus scrofa 17263 R-SSC-9023860 https://reactome.org/PathwayBrowser/#/R-SSC-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Sus scrofa 17263 R-SSC-9023861 https://reactome.org/PathwayBrowser/#/R-SSC-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 17263 R-SSC-9023884 https://reactome.org/PathwayBrowser/#/R-SSC-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Sus scrofa 17263 R-XTR-176664 https://reactome.org/PathwayBrowser/#/R-XTR-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Xenopus tropicalis 17263 R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 17263 R-XTR-5693390 https://reactome.org/PathwayBrowser/#/R-XTR-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Xenopus tropicalis 17263 R-XTR-5696822 https://reactome.org/PathwayBrowser/#/R-XTR-5696822 AKR1B15 reduces EST17b to E1 IEA Xenopus tropicalis 17263 R-XTR-6810594 https://reactome.org/PathwayBrowser/#/R-XTR-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 17263 R-XTR-804969 https://reactome.org/PathwayBrowser/#/R-XTR-804969 HSD17B1 hydrogenates E1 to EST17b IEA Xenopus tropicalis 17263 R-XTR-8862137 https://reactome.org/PathwayBrowser/#/R-XTR-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 17263 R-XTR-9008258 https://reactome.org/PathwayBrowser/#/R-XTR-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Xenopus tropicalis 17263 R-XTR-9008285 https://reactome.org/PathwayBrowser/#/R-XTR-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Xenopus tropicalis 17263 R-XTR-9023860 https://reactome.org/PathwayBrowser/#/R-XTR-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Xenopus tropicalis 17268 R-BTA-1482976 https://reactome.org/PathwayBrowser/#/R-BTA-1482976 CDP-DAG is converted to PI by CDIPT IEA Bos taurus 17268 R-BTA-1855154 https://reactome.org/PathwayBrowser/#/R-BTA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 17268 R-BTA-1855210 https://reactome.org/PathwayBrowser/#/R-BTA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 17268 R-BTA-1855211 https://reactome.org/PathwayBrowser/#/R-BTA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 17268 R-BTA-429101 https://reactome.org/PathwayBrowser/#/R-BTA-429101 HMIT co-transports myo-inositol with a proton IEA Bos taurus 17268 R-BTA-429571 https://reactome.org/PathwayBrowser/#/R-BTA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Bos taurus 17268 R-BTA-5678327 https://reactome.org/PathwayBrowser/#/R-BTA-5678327 MIOX oxidises Ins to GlcA IEA Bos taurus 17268 R-BTA-6813740 https://reactome.org/PathwayBrowser/#/R-BTA-6813740 GDE1 hydrolyzes GroPIns IEA Bos taurus 17268 R-CEL-1482976 https://reactome.org/PathwayBrowser/#/R-CEL-1482976 CDP-DAG is converted to PI by CDIPT IEA Caenorhabditis elegans 17268 R-CEL-1855154 https://reactome.org/PathwayBrowser/#/R-CEL-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 17268 R-CEL-1855210 https://reactome.org/PathwayBrowser/#/R-CEL-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 17268 R-CEL-1855211 https://reactome.org/PathwayBrowser/#/R-CEL-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 17268 R-CEL-429101 https://reactome.org/PathwayBrowser/#/R-CEL-429101 HMIT co-transports myo-inositol with a proton IEA Caenorhabditis elegans 17268 R-CEL-5678327 https://reactome.org/PathwayBrowser/#/R-CEL-5678327 MIOX oxidises Ins to GlcA IEA Caenorhabditis elegans 17268 R-CEL-6813740 https://reactome.org/PathwayBrowser/#/R-CEL-6813740 GDE1 hydrolyzes GroPIns IEA Caenorhabditis elegans 17268 R-CFA-1482976 https://reactome.org/PathwayBrowser/#/R-CFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Canis familiaris 17268 R-CFA-1855154 https://reactome.org/PathwayBrowser/#/R-CFA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 17268 R-CFA-1855210 https://reactome.org/PathwayBrowser/#/R-CFA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 17268 R-CFA-1855211 https://reactome.org/PathwayBrowser/#/R-CFA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 17268 R-CFA-429101 https://reactome.org/PathwayBrowser/#/R-CFA-429101 HMIT co-transports myo-inositol with a proton IEA Canis familiaris 17268 R-CFA-429571 https://reactome.org/PathwayBrowser/#/R-CFA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Canis familiaris 17268 R-CFA-429663 https://reactome.org/PathwayBrowser/#/R-CFA-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Canis familiaris 17268 R-CFA-5678327 https://reactome.org/PathwayBrowser/#/R-CFA-5678327 MIOX oxidises Ins to GlcA IEA Canis familiaris 17268 R-CFA-6813740 https://reactome.org/PathwayBrowser/#/R-CFA-6813740 GDE1 hydrolyzes GroPIns IEA Canis familiaris 17268 R-DDI-1482976 https://reactome.org/PathwayBrowser/#/R-DDI-1482976 CDP-DAG is converted to PI by CDIPT IEA Dictyostelium discoideum 17268 R-DDI-1855154 https://reactome.org/PathwayBrowser/#/R-DDI-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 17268 R-DDI-1855210 https://reactome.org/PathwayBrowser/#/R-DDI-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 17268 R-DDI-1855211 https://reactome.org/PathwayBrowser/#/R-DDI-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 17268 R-DDI-429101 https://reactome.org/PathwayBrowser/#/R-DDI-429101 HMIT co-transports myo-inositol with a proton IEA Dictyostelium discoideum 17268 R-DDI-5678327 https://reactome.org/PathwayBrowser/#/R-DDI-5678327 MIOX oxidises Ins to GlcA IEA Dictyostelium discoideum 17268 R-DME-1482976 https://reactome.org/PathwayBrowser/#/R-DME-1482976 CDP-DAG is converted to PI by CDIPT IEA Drosophila melanogaster 17268 R-DME-1855154 https://reactome.org/PathwayBrowser/#/R-DME-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 17268 R-DME-1855210 https://reactome.org/PathwayBrowser/#/R-DME-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 17268 R-DME-1855211 https://reactome.org/PathwayBrowser/#/R-DME-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 17268 R-DME-5678327 https://reactome.org/PathwayBrowser/#/R-DME-5678327 MIOX oxidises Ins to GlcA IEA Drosophila melanogaster 17268 R-DME-6813740 https://reactome.org/PathwayBrowser/#/R-DME-6813740 GDE1 hydrolyzes GroPIns IEA Drosophila melanogaster 17268 R-DRE-1482976 https://reactome.org/PathwayBrowser/#/R-DRE-1482976 CDP-DAG is converted to PI by CDIPT IEA Danio rerio 17268 R-DRE-1855154 https://reactome.org/PathwayBrowser/#/R-DRE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 17268 R-DRE-1855210 https://reactome.org/PathwayBrowser/#/R-DRE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 17268 R-DRE-1855211 https://reactome.org/PathwayBrowser/#/R-DRE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 17268 R-DRE-429571 https://reactome.org/PathwayBrowser/#/R-DRE-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Danio rerio 17268 R-DRE-5678327 https://reactome.org/PathwayBrowser/#/R-DRE-5678327 MIOX oxidises Ins to GlcA IEA Danio rerio 17268 R-DRE-6813740 https://reactome.org/PathwayBrowser/#/R-DRE-6813740 GDE1 hydrolyzes GroPIns IEA Danio rerio 17268 R-GGA-1855154 https://reactome.org/PathwayBrowser/#/R-GGA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 17268 R-GGA-1855210 https://reactome.org/PathwayBrowser/#/R-GGA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 17268 R-GGA-1855211 https://reactome.org/PathwayBrowser/#/R-GGA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 17268 R-GGA-429101 https://reactome.org/PathwayBrowser/#/R-GGA-429101 HMIT co-transports myo-inositol with a proton IEA Gallus gallus 17268 R-GGA-429571 https://reactome.org/PathwayBrowser/#/R-GGA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Gallus gallus 17268 R-GGA-5678327 https://reactome.org/PathwayBrowser/#/R-GGA-5678327 MIOX oxidises Ins to GlcA IEA Gallus gallus 17268 R-GGA-6813740 https://reactome.org/PathwayBrowser/#/R-GGA-6813740 GDE1 hydrolyzes GroPIns IEA Gallus gallus 17268 R-HSA-1482976 https://reactome.org/PathwayBrowser/#/R-HSA-1482976 CDP-DAG is converted to PI by CDIPT TAS Homo sapiens 17268 R-HSA-1855154 https://reactome.org/PathwayBrowser/#/R-HSA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 17268 R-HSA-1855210 https://reactome.org/PathwayBrowser/#/R-HSA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 17268 R-HSA-1855211 https://reactome.org/PathwayBrowser/#/R-HSA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 17268 R-HSA-429101 https://reactome.org/PathwayBrowser/#/R-HSA-429101 HMIT co-transports myo-inositol with a proton TAS Homo sapiens 17268 R-HSA-429571 https://reactome.org/PathwayBrowser/#/R-HSA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 TAS Homo sapiens 17268 R-HSA-429663 https://reactome.org/PathwayBrowser/#/R-HSA-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol TAS Homo sapiens 17268 R-HSA-5678327 https://reactome.org/PathwayBrowser/#/R-HSA-5678327 MIOX oxidises Ins to GlcA TAS Homo sapiens 17268 R-HSA-6813740 https://reactome.org/PathwayBrowser/#/R-HSA-6813740 GDE1 hydrolyzes GroPIns TAS Homo sapiens 17268 R-MMU-1482976 https://reactome.org/PathwayBrowser/#/R-MMU-1482976 CDP-DAG is converted to PI by CDIPT IEA Mus musculus 17268 R-MMU-1855154 https://reactome.org/PathwayBrowser/#/R-MMU-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 17268 R-MMU-1855210 https://reactome.org/PathwayBrowser/#/R-MMU-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 17268 R-MMU-1855211 https://reactome.org/PathwayBrowser/#/R-MMU-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 17268 R-MMU-429101 https://reactome.org/PathwayBrowser/#/R-MMU-429101 HMIT co-transports myo-inositol with a proton IEA Mus musculus 17268 R-MMU-429571 https://reactome.org/PathwayBrowser/#/R-MMU-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Mus musculus 17268 R-MMU-429663 https://reactome.org/PathwayBrowser/#/R-MMU-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Mus musculus 17268 R-MMU-5678327 https://reactome.org/PathwayBrowser/#/R-MMU-5678327 MIOX oxidises Ins to GlcA IEA Mus musculus 17268 R-MMU-6813740 https://reactome.org/PathwayBrowser/#/R-MMU-6813740 GDE1 hydrolyzes GroPIns IEA Mus musculus 17268 R-PFA-1482976 https://reactome.org/PathwayBrowser/#/R-PFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Plasmodium falciparum 17268 R-RNO-1482976 https://reactome.org/PathwayBrowser/#/R-RNO-1482976 CDP-DAG is converted to PI by CDIPT IEA Rattus norvegicus 17268 R-RNO-1855154 https://reactome.org/PathwayBrowser/#/R-RNO-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 17268 R-RNO-1855210 https://reactome.org/PathwayBrowser/#/R-RNO-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 17268 R-RNO-1855211 https://reactome.org/PathwayBrowser/#/R-RNO-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 17268 R-RNO-429101 https://reactome.org/PathwayBrowser/#/R-RNO-429101 HMIT co-transports myo-inositol with a proton IEA Rattus norvegicus 17268 R-RNO-429571 https://reactome.org/PathwayBrowser/#/R-RNO-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Rattus norvegicus 17268 R-RNO-429663 https://reactome.org/PathwayBrowser/#/R-RNO-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Rattus norvegicus 17268 R-RNO-5678327 https://reactome.org/PathwayBrowser/#/R-RNO-5678327 MIOX oxidises Ins to GlcA IEA Rattus norvegicus 17268 R-RNO-6813740 https://reactome.org/PathwayBrowser/#/R-RNO-6813740 GDE1 hydrolyzes GroPIns IEA Rattus norvegicus 17268 R-SCE-1482976 https://reactome.org/PathwayBrowser/#/R-SCE-1482976 CDP-DAG is converted to PI by CDIPT IEA Saccharomyces cerevisiae 17268 R-SCE-1855154 https://reactome.org/PathwayBrowser/#/R-SCE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 17268 R-SCE-1855210 https://reactome.org/PathwayBrowser/#/R-SCE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 17268 R-SCE-1855211 https://reactome.org/PathwayBrowser/#/R-SCE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 17268 R-SCE-429101 https://reactome.org/PathwayBrowser/#/R-SCE-429101 HMIT co-transports myo-inositol with a proton IEA Saccharomyces cerevisiae 17268 R-SPO-1482976 https://reactome.org/PathwayBrowser/#/R-SPO-1482976 CDP-DAG is converted to PI by CDIPT IEA Schizosaccharomyces pombe 17268 R-SPO-429101 https://reactome.org/PathwayBrowser/#/R-SPO-429101 HMIT co-transports myo-inositol with a proton IEA Schizosaccharomyces pombe 17268 R-SSC-1482976 https://reactome.org/PathwayBrowser/#/R-SSC-1482976 CDP-DAG is converted to PI by CDIPT IEA Sus scrofa 17268 R-SSC-1855154 https://reactome.org/PathwayBrowser/#/R-SSC-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 17268 R-SSC-1855210 https://reactome.org/PathwayBrowser/#/R-SSC-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 17268 R-SSC-1855211 https://reactome.org/PathwayBrowser/#/R-SSC-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 17268 R-SSC-429101 https://reactome.org/PathwayBrowser/#/R-SSC-429101 HMIT co-transports myo-inositol with a proton IEA Sus scrofa 17268 R-SSC-429571 https://reactome.org/PathwayBrowser/#/R-SSC-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Sus scrofa 17268 R-SSC-429663 https://reactome.org/PathwayBrowser/#/R-SSC-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Sus scrofa 17268 R-SSC-5678327 https://reactome.org/PathwayBrowser/#/R-SSC-5678327 MIOX oxidises Ins to GlcA IEA Sus scrofa 17268 R-SSC-6813740 https://reactome.org/PathwayBrowser/#/R-SSC-6813740 GDE1 hydrolyzes GroPIns IEA Sus scrofa 17268 R-XTR-1482976 https://reactome.org/PathwayBrowser/#/R-XTR-1482976 CDP-DAG is converted to PI by CDIPT IEA Xenopus tropicalis 17268 R-XTR-1855154 https://reactome.org/PathwayBrowser/#/R-XTR-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 17268 R-XTR-1855210 https://reactome.org/PathwayBrowser/#/R-XTR-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 17268 R-XTR-1855211 https://reactome.org/PathwayBrowser/#/R-XTR-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 17268 R-XTR-429101 https://reactome.org/PathwayBrowser/#/R-XTR-429101 HMIT co-transports myo-inositol with a proton IEA Xenopus tropicalis 17268 R-XTR-429571 https://reactome.org/PathwayBrowser/#/R-XTR-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Xenopus tropicalis 17268 R-XTR-6813740 https://reactome.org/PathwayBrowser/#/R-XTR-6813740 GDE1 hydrolyzes GroPIns IEA Xenopus tropicalis 17278 R-BTA-191999 https://reactome.org/PathwayBrowser/#/R-BTA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Bos taurus 17278 R-BTA-192042 https://reactome.org/PathwayBrowser/#/R-BTA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 17278 R-BTA-193800 https://reactome.org/PathwayBrowser/#/R-BTA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Bos taurus 17278 R-CEL-193800 https://reactome.org/PathwayBrowser/#/R-CEL-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Caenorhabditis elegans 17278 R-CFA-191999 https://reactome.org/PathwayBrowser/#/R-CFA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Canis familiaris 17278 R-CFA-192042 https://reactome.org/PathwayBrowser/#/R-CFA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 17278 R-DDI-193800 https://reactome.org/PathwayBrowser/#/R-DDI-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Dictyostelium discoideum 17278 R-DME-193800 https://reactome.org/PathwayBrowser/#/R-DME-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Drosophila melanogaster 17278 R-HSA-191999 https://reactome.org/PathwayBrowser/#/R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol TAS Homo sapiens 17278 R-HSA-192042 https://reactome.org/PathwayBrowser/#/R-HSA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 17278 R-HSA-193800 https://reactome.org/PathwayBrowser/#/R-HSA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol TAS Homo sapiens 17278 R-HSA-193832 https://reactome.org/PathwayBrowser/#/R-HSA-193832 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix TAS Homo sapiens 17278 R-MMU-191999 https://reactome.org/PathwayBrowser/#/R-MMU-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Mus musculus 17278 R-MMU-192042 https://reactome.org/PathwayBrowser/#/R-MMU-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 17278 R-MMU-193800 https://reactome.org/PathwayBrowser/#/R-MMU-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Mus musculus 17278 R-RNO-191999 https://reactome.org/PathwayBrowser/#/R-RNO-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Rattus norvegicus 17278 R-RNO-192042 https://reactome.org/PathwayBrowser/#/R-RNO-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 17278 R-RNO-193800 https://reactome.org/PathwayBrowser/#/R-RNO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Rattus norvegicus 17278 R-SCE-193800 https://reactome.org/PathwayBrowser/#/R-SCE-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Saccharomyces cerevisiae 17278 R-SPO-193800 https://reactome.org/PathwayBrowser/#/R-SPO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Schizosaccharomyces pombe 17278 R-SSC-191999 https://reactome.org/PathwayBrowser/#/R-SSC-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Sus scrofa 17278 R-SSC-192042 https://reactome.org/PathwayBrowser/#/R-SSC-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 17278 R-SSC-193800 https://reactome.org/PathwayBrowser/#/R-SSC-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Sus scrofa 17278 R-XTR-193800 https://reactome.org/PathwayBrowser/#/R-XTR-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Xenopus tropicalis 17285 R-BTA-6787757 https://reactome.org/PathwayBrowser/#/R-BTA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Bos taurus 17285 R-CFA-6787757 https://reactome.org/PathwayBrowser/#/R-CFA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Canis familiaris 17285 R-DME-6787757 https://reactome.org/PathwayBrowser/#/R-DME-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Drosophila melanogaster 17285 R-GGA-6787757 https://reactome.org/PathwayBrowser/#/R-GGA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Gallus gallus 17285 R-HSA-6787757 https://reactome.org/PathwayBrowser/#/R-HSA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs TAS Homo sapiens 17285 R-MMU-6787757 https://reactome.org/PathwayBrowser/#/R-MMU-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Mus musculus 17285 R-RNO-6787757 https://reactome.org/PathwayBrowser/#/R-RNO-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Rattus norvegicus 17285 R-SSC-6787757 https://reactome.org/PathwayBrowser/#/R-SSC-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Sus scrofa 17285 R-XTR-6787757 https://reactome.org/PathwayBrowser/#/R-XTR-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Xenopus tropicalis 172871 R-BTA-9731228 https://reactome.org/PathwayBrowser/#/R-BTA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Bos taurus 172871 R-CFA-9731228 https://reactome.org/PathwayBrowser/#/R-CFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Canis familiaris 172871 R-DRE-9731228 https://reactome.org/PathwayBrowser/#/R-DRE-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Danio rerio 172871 R-GGA-9731228 https://reactome.org/PathwayBrowser/#/R-GGA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Gallus gallus 172871 R-HSA-9731228 https://reactome.org/PathwayBrowser/#/R-HSA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP TAS Homo sapiens 172871 R-MMU-9731228 https://reactome.org/PathwayBrowser/#/R-MMU-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Mus musculus 172871 R-PFA-9731228 https://reactome.org/PathwayBrowser/#/R-PFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Plasmodium falciparum 172871 R-RNO-9731228 https://reactome.org/PathwayBrowser/#/R-RNO-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Rattus norvegicus 172871 R-SSC-9731228 https://reactome.org/PathwayBrowser/#/R-SSC-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Sus scrofa 172871 R-XTR-9731228 https://reactome.org/PathwayBrowser/#/R-XTR-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Xenopus tropicalis 172872 R-BTA-9731613 https://reactome.org/PathwayBrowser/#/R-BTA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Bos taurus 172872 R-CFA-9731613 https://reactome.org/PathwayBrowser/#/R-CFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Canis familiaris 172872 R-DRE-9731613 https://reactome.org/PathwayBrowser/#/R-DRE-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Danio rerio 172872 R-GGA-9731613 https://reactome.org/PathwayBrowser/#/R-GGA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Gallus gallus 172872 R-HSA-9731613 https://reactome.org/PathwayBrowser/#/R-HSA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP TAS Homo sapiens 172872 R-MMU-9731613 https://reactome.org/PathwayBrowser/#/R-MMU-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Mus musculus 172872 R-PFA-9731613 https://reactome.org/PathwayBrowser/#/R-PFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Plasmodium falciparum 172872 R-RNO-9731613 https://reactome.org/PathwayBrowser/#/R-RNO-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Rattus norvegicus 172872 R-SSC-9731613 https://reactome.org/PathwayBrowser/#/R-SSC-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Sus scrofa 172872 R-XTR-9731613 https://reactome.org/PathwayBrowser/#/R-XTR-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Xenopus tropicalis 172873 R-BTA-9731632 https://reactome.org/PathwayBrowser/#/R-BTA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Bos taurus 172873 R-CFA-9731632 https://reactome.org/PathwayBrowser/#/R-CFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Canis familiaris 172873 R-DRE-9731632 https://reactome.org/PathwayBrowser/#/R-DRE-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Danio rerio 172873 R-GGA-9731632 https://reactome.org/PathwayBrowser/#/R-GGA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Gallus gallus 172873 R-HSA-9731632 https://reactome.org/PathwayBrowser/#/R-HSA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP TAS Homo sapiens 172873 R-MMU-9731632 https://reactome.org/PathwayBrowser/#/R-MMU-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Mus musculus 172873 R-PFA-9731632 https://reactome.org/PathwayBrowser/#/R-PFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Plasmodium falciparum 172873 R-RNO-9731632 https://reactome.org/PathwayBrowser/#/R-RNO-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Rattus norvegicus 172873 R-SSC-9731632 https://reactome.org/PathwayBrowser/#/R-SSC-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Sus scrofa 172873 R-XTR-9731632 https://reactome.org/PathwayBrowser/#/R-XTR-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Xenopus tropicalis 172878 R-BTA-2395872 https://reactome.org/PathwayBrowser/#/R-BTA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Bos taurus 172878 R-CFA-2395872 https://reactome.org/PathwayBrowser/#/R-CFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Canis familiaris 172878 R-DRE-2395872 https://reactome.org/PathwayBrowser/#/R-DRE-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Danio rerio 172878 R-GGA-2395872 https://reactome.org/PathwayBrowser/#/R-GGA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Gallus gallus 172878 R-HSA-2395872 https://reactome.org/PathwayBrowser/#/R-HSA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP TAS Homo sapiens 172878 R-MMU-2395872 https://reactome.org/PathwayBrowser/#/R-MMU-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Mus musculus 172878 R-PFA-2395872 https://reactome.org/PathwayBrowser/#/R-PFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Plasmodium falciparum 172878 R-RNO-2395872 https://reactome.org/PathwayBrowser/#/R-RNO-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Rattus norvegicus 172878 R-SSC-2395872 https://reactome.org/PathwayBrowser/#/R-SSC-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Sus scrofa 172878 R-XTR-2395872 https://reactome.org/PathwayBrowser/#/R-XTR-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Xenopus tropicalis 172918 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 172918 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 172918 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 172918 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 172918 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 172918 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 172918 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 172918 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 17306 R-BTA-188979 https://reactome.org/PathwayBrowser/#/R-BTA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Bos taurus 17306 R-BTA-189053 https://reactome.org/PathwayBrowser/#/R-BTA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Bos taurus 17306 R-BTA-189102 https://reactome.org/PathwayBrowser/#/R-BTA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Bos taurus 17306 R-BTA-191101 https://reactome.org/PathwayBrowser/#/R-BTA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Bos taurus 17306 R-BTA-191108 https://reactome.org/PathwayBrowser/#/R-BTA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Bos taurus 17306 R-BTA-191114 https://reactome.org/PathwayBrowser/#/R-BTA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Bos taurus 17306 R-BTA-191116 https://reactome.org/PathwayBrowser/#/R-BTA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Bos taurus 17306 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 17306 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 17306 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 17306 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 17306 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 17306 R-CEL-188979 https://reactome.org/PathwayBrowser/#/R-CEL-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Caenorhabditis elegans 17306 R-CEL-189053 https://reactome.org/PathwayBrowser/#/R-CEL-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Caenorhabditis elegans 17306 R-CEL-189102 https://reactome.org/PathwayBrowser/#/R-CEL-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Caenorhabditis elegans 17306 R-CEL-191101 https://reactome.org/PathwayBrowser/#/R-CEL-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 17306 R-CEL-191108 https://reactome.org/PathwayBrowser/#/R-CEL-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 17306 R-CEL-191114 https://reactome.org/PathwayBrowser/#/R-CEL-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Caenorhabditis elegans 17306 R-CEL-191116 https://reactome.org/PathwayBrowser/#/R-CEL-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Caenorhabditis elegans 17306 R-CFA-188979 https://reactome.org/PathwayBrowser/#/R-CFA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Canis familiaris 17306 R-CFA-189053 https://reactome.org/PathwayBrowser/#/R-CFA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Canis familiaris 17306 R-CFA-189102 https://reactome.org/PathwayBrowser/#/R-CFA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Canis familiaris 17306 R-CFA-191101 https://reactome.org/PathwayBrowser/#/R-CFA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Canis familiaris 17306 R-CFA-191108 https://reactome.org/PathwayBrowser/#/R-CFA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Canis familiaris 17306 R-CFA-191114 https://reactome.org/PathwayBrowser/#/R-CFA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Canis familiaris 17306 R-CFA-191116 https://reactome.org/PathwayBrowser/#/R-CFA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Canis familiaris 17306 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 17306 R-DDI-189053 https://reactome.org/PathwayBrowser/#/R-DDI-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Dictyostelium discoideum 17306 R-DDI-189102 https://reactome.org/PathwayBrowser/#/R-DDI-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Dictyostelium discoideum 17306 R-DDI-191101 https://reactome.org/PathwayBrowser/#/R-DDI-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 17306 R-DDI-191108 https://reactome.org/PathwayBrowser/#/R-DDI-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 17306 R-DDI-191116 https://reactome.org/PathwayBrowser/#/R-DDI-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Dictyostelium discoideum 17306 R-DME-188979 https://reactome.org/PathwayBrowser/#/R-DME-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Drosophila melanogaster 17306 R-DME-191114 https://reactome.org/PathwayBrowser/#/R-DME-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Drosophila melanogaster 17306 R-DRE-188979 https://reactome.org/PathwayBrowser/#/R-DRE-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Danio rerio 17306 R-DRE-191114 https://reactome.org/PathwayBrowser/#/R-DRE-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Danio rerio 17306 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 17306 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 17306 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 17306 R-GGA-188979 https://reactome.org/PathwayBrowser/#/R-GGA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Gallus gallus 17306 R-GGA-189053 https://reactome.org/PathwayBrowser/#/R-GGA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Gallus gallus 17306 R-GGA-189102 https://reactome.org/PathwayBrowser/#/R-GGA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Gallus gallus 17306 R-GGA-191101 https://reactome.org/PathwayBrowser/#/R-GGA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Gallus gallus 17306 R-GGA-191108 https://reactome.org/PathwayBrowser/#/R-GGA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus 17306 R-GGA-191114 https://reactome.org/PathwayBrowser/#/R-GGA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Gallus gallus 17306 R-GGA-191116 https://reactome.org/PathwayBrowser/#/R-GGA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Gallus gallus 17306 R-HSA-188979 https://reactome.org/PathwayBrowser/#/R-HSA-188979 Digestion of linear starch (amylose) by extracellular amylase TAS Homo sapiens 17306 R-HSA-189053 https://reactome.org/PathwayBrowser/#/R-HSA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose TAS Homo sapiens 17306 R-HSA-189102 https://reactome.org/PathwayBrowser/#/R-HSA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) TAS Homo sapiens 17306 R-HSA-191101 https://reactome.org/PathwayBrowser/#/R-HSA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) TAS Homo sapiens 17306 R-HSA-191108 https://reactome.org/PathwayBrowser/#/R-HSA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) TAS Homo sapiens 17306 R-HSA-191114 https://reactome.org/PathwayBrowser/#/R-HSA-191114 Digestion of branched starch (amylopectin) by extracellular amylase TAS Homo sapiens 17306 R-HSA-191116 https://reactome.org/PathwayBrowser/#/R-HSA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) TAS Homo sapiens 17306 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 17306 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 17306 R-HSA-5659922 https://reactome.org/PathwayBrowser/#/R-HSA-5659922 Defective SI does not hydrolyze Mal TAS Homo sapiens 17306 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 17306 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 17306 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 17306 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 17306 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 17306 R-MMU-188979 https://reactome.org/PathwayBrowser/#/R-MMU-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Mus musculus 17306 R-MMU-189053 https://reactome.org/PathwayBrowser/#/R-MMU-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Mus musculus 17306 R-MMU-189102 https://reactome.org/PathwayBrowser/#/R-MMU-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Mus musculus 17306 R-MMU-191101 https://reactome.org/PathwayBrowser/#/R-MMU-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Mus musculus 17306 R-MMU-191108 https://reactome.org/PathwayBrowser/#/R-MMU-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Mus musculus 17306 R-MMU-191114 https://reactome.org/PathwayBrowser/#/R-MMU-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Mus musculus 17306 R-MMU-191116 https://reactome.org/PathwayBrowser/#/R-MMU-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Mus musculus 17306 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 17306 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 17306 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 17306 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 17306 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 17306 R-MTU-868709 https://reactome.org/PathwayBrowser/#/R-MTU-868709 Maltose is converted to trehalose TAS Mycobacterium tuberculosis 17306 R-RNO-188979 https://reactome.org/PathwayBrowser/#/R-RNO-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Rattus norvegicus 17306 R-RNO-189053 https://reactome.org/PathwayBrowser/#/R-RNO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Rattus norvegicus 17306 R-RNO-191101 https://reactome.org/PathwayBrowser/#/R-RNO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 17306 R-RNO-191108 https://reactome.org/PathwayBrowser/#/R-RNO-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 17306 R-RNO-191114 https://reactome.org/PathwayBrowser/#/R-RNO-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Rattus norvegicus 17306 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 17306 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 17306 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 17306 R-SPO-189053 https://reactome.org/PathwayBrowser/#/R-SPO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Schizosaccharomyces pombe 17306 R-SPO-189102 https://reactome.org/PathwayBrowser/#/R-SPO-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Schizosaccharomyces pombe 17306 R-SPO-191101 https://reactome.org/PathwayBrowser/#/R-SPO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 17306 R-SPO-191108 https://reactome.org/PathwayBrowser/#/R-SPO-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 17306 R-SPO-191116 https://reactome.org/PathwayBrowser/#/R-SPO-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Schizosaccharomyces pombe 17306 R-SSC-188979 https://reactome.org/PathwayBrowser/#/R-SSC-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Sus scrofa 17306 R-SSC-189053 https://reactome.org/PathwayBrowser/#/R-SSC-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Sus scrofa 17306 R-SSC-189102 https://reactome.org/PathwayBrowser/#/R-SSC-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Sus scrofa 17306 R-SSC-191101 https://reactome.org/PathwayBrowser/#/R-SSC-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Sus scrofa 17306 R-SSC-191108 https://reactome.org/PathwayBrowser/#/R-SSC-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Sus scrofa 17306 R-SSC-191114 https://reactome.org/PathwayBrowser/#/R-SSC-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Sus scrofa 17306 R-SSC-191116 https://reactome.org/PathwayBrowser/#/R-SSC-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Sus scrofa 17306 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 17306 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 17306 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 17306 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 17306 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 17306 R-XTR-188979 https://reactome.org/PathwayBrowser/#/R-XTR-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Xenopus tropicalis 17306 R-XTR-191114 https://reactome.org/PathwayBrowser/#/R-XTR-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Xenopus tropicalis 17310 R-BTA-3204311 https://reactome.org/PathwayBrowser/#/R-BTA-3204311 AOX1 oxidises PXL to PDXate IEA Bos taurus 17310 R-BTA-964970 https://reactome.org/PathwayBrowser/#/R-BTA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Bos taurus 17310 R-CEL-3204311 https://reactome.org/PathwayBrowser/#/R-CEL-3204311 AOX1 oxidises PXL to PDXate IEA Caenorhabditis elegans 17310 R-CEL-964970 https://reactome.org/PathwayBrowser/#/R-CEL-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Caenorhabditis elegans 17310 R-CFA-964970 https://reactome.org/PathwayBrowser/#/R-CFA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Canis familiaris 17310 R-DDI-3204311 https://reactome.org/PathwayBrowser/#/R-DDI-3204311 AOX1 oxidises PXL to PDXate IEA Dictyostelium discoideum 17310 R-DDI-964970 https://reactome.org/PathwayBrowser/#/R-DDI-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Dictyostelium discoideum 17310 R-DME-3204311 https://reactome.org/PathwayBrowser/#/R-DME-3204311 AOX1 oxidises PXL to PDXate IEA Drosophila melanogaster 17310 R-DME-964970 https://reactome.org/PathwayBrowser/#/R-DME-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Drosophila melanogaster 17310 R-DRE-3204311 https://reactome.org/PathwayBrowser/#/R-DRE-3204311 AOX1 oxidises PXL to PDXate IEA Danio rerio 17310 R-DRE-964970 https://reactome.org/PathwayBrowser/#/R-DRE-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Danio rerio 17310 R-GGA-3204311 https://reactome.org/PathwayBrowser/#/R-GGA-3204311 AOX1 oxidises PXL to PDXate IEA Gallus gallus 17310 R-GGA-964970 https://reactome.org/PathwayBrowser/#/R-GGA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Gallus gallus 17310 R-HSA-3204311 https://reactome.org/PathwayBrowser/#/R-HSA-3204311 AOX1 oxidises PXL to PDXate TAS Homo sapiens 17310 R-HSA-964970 https://reactome.org/PathwayBrowser/#/R-HSA-964970 2xPDXK:2xZn2+ phosphorylates PXL TAS Homo sapiens 17310 R-MMU-3204311 https://reactome.org/PathwayBrowser/#/R-MMU-3204311 AOX1 oxidises PXL to PDXate IEA Mus musculus 17310 R-MMU-964970 https://reactome.org/PathwayBrowser/#/R-MMU-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Mus musculus 17310 R-PFA-964970 https://reactome.org/PathwayBrowser/#/R-PFA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Plasmodium falciparum 17310 R-RNO-3204311 https://reactome.org/PathwayBrowser/#/R-RNO-3204311 AOX1 oxidises PXL to PDXate IEA Rattus norvegicus 17310 R-RNO-964970 https://reactome.org/PathwayBrowser/#/R-RNO-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Rattus norvegicus 17310 R-SCE-964970 https://reactome.org/PathwayBrowser/#/R-SCE-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Saccharomyces cerevisiae 17310 R-SPO-964970 https://reactome.org/PathwayBrowser/#/R-SPO-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Schizosaccharomyces pombe 17310 R-SSC-3204311 https://reactome.org/PathwayBrowser/#/R-SSC-3204311 AOX1 oxidises PXL to PDXate IEA Sus scrofa 17310 R-SSC-964970 https://reactome.org/PathwayBrowser/#/R-SSC-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Sus scrofa 17310 R-XTR-3204311 https://reactome.org/PathwayBrowser/#/R-XTR-3204311 AOX1 oxidises PXL to PDXate IEA Xenopus tropicalis 17310 R-XTR-964970 https://reactome.org/PathwayBrowser/#/R-XTR-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Xenopus tropicalis 17319 R-BTA-6793591 https://reactome.org/PathwayBrowser/#/R-BTA-6793591 LIAS synthesizes lipoyl-GCSH IEA Bos taurus 17319 R-BTA-947535 https://reactome.org/PathwayBrowser/#/R-BTA-947535 Cyclisation of GTP to precursor Z IEA Bos taurus 17319 R-CEL-947535 https://reactome.org/PathwayBrowser/#/R-CEL-947535 Cyclisation of GTP to precursor Z IEA Caenorhabditis elegans 17319 R-CFA-6793591 https://reactome.org/PathwayBrowser/#/R-CFA-6793591 LIAS synthesizes lipoyl-GCSH IEA Canis familiaris 17319 R-CFA-947535 https://reactome.org/PathwayBrowser/#/R-CFA-947535 Cyclisation of GTP to precursor Z IEA Canis familiaris 17319 R-DDI-947535 https://reactome.org/PathwayBrowser/#/R-DDI-947535 Cyclisation of GTP to precursor Z IEA Dictyostelium discoideum 17319 R-DME-6793591 https://reactome.org/PathwayBrowser/#/R-DME-6793591 LIAS synthesizes lipoyl-GCSH IEA Drosophila melanogaster 17319 R-DME-947535 https://reactome.org/PathwayBrowser/#/R-DME-947535 Cyclisation of GTP to precursor Z IEA Drosophila melanogaster 17319 R-DRE-6793591 https://reactome.org/PathwayBrowser/#/R-DRE-6793591 LIAS synthesizes lipoyl-GCSH IEA Danio rerio 17319 R-GGA-6793591 https://reactome.org/PathwayBrowser/#/R-GGA-6793591 LIAS synthesizes lipoyl-GCSH IEA Gallus gallus 17319 R-GGA-947535 https://reactome.org/PathwayBrowser/#/R-GGA-947535 Cyclisation of GTP to precursor Z IEA Gallus gallus 17319 R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 17319 R-HSA-6793591 https://reactome.org/PathwayBrowser/#/R-HSA-6793591 LIAS synthesizes lipoyl-GCSH TAS Homo sapiens 17319 R-HSA-947535 https://reactome.org/PathwayBrowser/#/R-HSA-947535 Cyclisation of GTP to precursor Z TAS Homo sapiens 17319 R-MMU-6793591 https://reactome.org/PathwayBrowser/#/R-MMU-6793591 LIAS synthesizes lipoyl-GCSH IEA Mus musculus 17319 R-MMU-947535 https://reactome.org/PathwayBrowser/#/R-MMU-947535 Cyclisation of GTP to precursor Z IEA Mus musculus 17319 R-RNO-6793591 https://reactome.org/PathwayBrowser/#/R-RNO-6793591 LIAS synthesizes lipoyl-GCSH IEA Rattus norvegicus 17319 R-RNO-947535 https://reactome.org/PathwayBrowser/#/R-RNO-947535 Cyclisation of GTP to precursor Z IEA Rattus norvegicus 17319 R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 17319 R-SSC-6793591 https://reactome.org/PathwayBrowser/#/R-SSC-6793591 LIAS synthesizes lipoyl-GCSH IEA Sus scrofa 17319 R-SSC-947535 https://reactome.org/PathwayBrowser/#/R-SSC-947535 Cyclisation of GTP to precursor Z IEA Sus scrofa 17319 R-XTR-947535 https://reactome.org/PathwayBrowser/#/R-XTR-947535 Cyclisation of GTP to precursor Z IEA Xenopus tropicalis 17333 R-MTU-964884 https://reactome.org/PathwayBrowser/#/R-MTU-964884 Dephosphorylation of EPSP yields chorismate TAS Mycobacterium tuberculosis 17336 R-BTA-2404134 https://reactome.org/PathwayBrowser/#/R-BTA-2404134 RBP4:atROL binds TTR IEA Bos taurus 17336 R-BTA-2404135 https://reactome.org/PathwayBrowser/#/R-BTA-2404135 RBP4 binds atROL IEA Bos taurus 17336 R-BTA-2404137 https://reactome.org/PathwayBrowser/#/R-BTA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 17336 R-BTA-2404142 https://reactome.org/PathwayBrowser/#/R-BTA-2404142 atROL binds RBP1 IEA Bos taurus 17336 R-BTA-2404144 https://reactome.org/PathwayBrowser/#/R-BTA-2404144 Parenchymal atROL translocates to HSCs IEA Bos taurus 17336 R-BTA-2453855 https://reactome.org/PathwayBrowser/#/R-BTA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 17336 R-BTA-2453863 https://reactome.org/PathwayBrowser/#/R-BTA-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Bos taurus 17336 R-BTA-2453876 https://reactome.org/PathwayBrowser/#/R-BTA-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Bos taurus 17336 R-BTA-2464776 https://reactome.org/PathwayBrowser/#/R-BTA-2464776 Rdh8 reduces atRAL to atROL TAS Bos taurus 17336 R-BTA-2464809 https://reactome.org/PathwayBrowser/#/R-BTA-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Bos taurus 17336 R-BTA-2464822 https://reactome.org/PathwayBrowser/#/R-BTA-2464822 RDH12 reduces atRAL to atROL IEA Bos taurus 17336 R-BTA-2465938 https://reactome.org/PathwayBrowser/#/R-BTA-2465938 RBP3 regulates atROL taken up by Muller cells IEA Bos taurus 17336 R-BTA-2465940 https://reactome.org/PathwayBrowser/#/R-BTA-2465940 atRAL is reduced to atROL IEA Bos taurus 17336 R-BTA-2465971 https://reactome.org/PathwayBrowser/#/R-BTA-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Bos taurus 17336 R-BTA-2855252 https://reactome.org/PathwayBrowser/#/R-BTA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Bos taurus 17336 R-BTA-2855259 https://reactome.org/PathwayBrowser/#/R-BTA-2855259 atROL binds RBP1 (parenchymal cell) IEA Bos taurus 17336 R-BTA-5246478 https://reactome.org/PathwayBrowser/#/R-BTA-5246478 APOM binds retinoids IEA Bos taurus 17336 R-BTA-5362518 https://reactome.org/PathwayBrowser/#/R-BTA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Bos taurus 17336 R-BTA-5362564 https://reactome.org/PathwayBrowser/#/R-BTA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Bos taurus 17336 R-BTA-5419165 https://reactome.org/PathwayBrowser/#/R-BTA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Bos taurus 17336 R-BTA-5615668 https://reactome.org/PathwayBrowser/#/R-BTA-5615668 AKR1C3 reduces atRAL to atROL IEA Bos taurus 17336 R-BTA-5623643 https://reactome.org/PathwayBrowser/#/R-BTA-5623643 RDH13 reduces atRAL to atROL IEA Bos taurus 17336 R-BTA-74843 https://reactome.org/PathwayBrowser/#/R-BTA-74843 atROL binds RBP1 to form RBP1:atROL IEA Bos taurus 17336 R-BTA-8848355 https://reactome.org/PathwayBrowser/#/R-BTA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Bos taurus 17336 R-BTA-8848585 https://reactome.org/PathwayBrowser/#/R-BTA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Bos taurus 17336 R-BTA-975593 https://reactome.org/PathwayBrowser/#/R-BTA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Bos taurus 17336 R-BTA-975594 https://reactome.org/PathwayBrowser/#/R-BTA-975594 PLB1 hydrolyses RPALM to atROL IEA Bos taurus 17336 R-BTA-975608 https://reactome.org/PathwayBrowser/#/R-BTA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Bos taurus 17336 R-BTA-975629 https://reactome.org/PathwayBrowser/#/R-BTA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Bos taurus 17336 R-BTA-975633 https://reactome.org/PathwayBrowser/#/R-BTA-975633 atROL binds to RBP2 IEA Bos taurus 17336 R-CEL-2404134 https://reactome.org/PathwayBrowser/#/R-CEL-2404134 RBP4:atROL binds TTR IEA Caenorhabditis elegans 17336 R-CEL-2404135 https://reactome.org/PathwayBrowser/#/R-CEL-2404135 RBP4 binds atROL IEA Caenorhabditis elegans 17336 R-CEL-2404142 https://reactome.org/PathwayBrowser/#/R-CEL-2404142 atROL binds RBP1 IEA Caenorhabditis elegans 17336 R-CEL-2404144 https://reactome.org/PathwayBrowser/#/R-CEL-2404144 Parenchymal atROL translocates to HSCs IEA Caenorhabditis elegans 17336 R-CEL-2465940 https://reactome.org/PathwayBrowser/#/R-CEL-2465940 atRAL is reduced to atROL IEA Caenorhabditis elegans 17336 R-CEL-2855252 https://reactome.org/PathwayBrowser/#/R-CEL-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Caenorhabditis elegans 17336 R-CEL-2855259 https://reactome.org/PathwayBrowser/#/R-CEL-2855259 atROL binds RBP1 (parenchymal cell) IEA Caenorhabditis elegans 17336 R-CEL-5362518 https://reactome.org/PathwayBrowser/#/R-CEL-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Caenorhabditis elegans 17336 R-CEL-5362564 https://reactome.org/PathwayBrowser/#/R-CEL-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Caenorhabditis elegans 17336 R-CEL-5419165 https://reactome.org/PathwayBrowser/#/R-CEL-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Caenorhabditis elegans 17336 R-CEL-5615668 https://reactome.org/PathwayBrowser/#/R-CEL-5615668 AKR1C3 reduces atRAL to atROL IEA Caenorhabditis elegans 17336 R-CEL-5623643 https://reactome.org/PathwayBrowser/#/R-CEL-5623643 RDH13 reduces atRAL to atROL IEA Caenorhabditis elegans 17336 R-CEL-74843 https://reactome.org/PathwayBrowser/#/R-CEL-74843 atROL binds RBP1 to form RBP1:atROL IEA Caenorhabditis elegans 17336 R-CEL-8848585 https://reactome.org/PathwayBrowser/#/R-CEL-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Caenorhabditis elegans 17336 R-CEL-975594 https://reactome.org/PathwayBrowser/#/R-CEL-975594 PLB1 hydrolyses RPALM to atROL IEA Caenorhabditis elegans 17336 R-CEL-975633 https://reactome.org/PathwayBrowser/#/R-CEL-975633 atROL binds to RBP2 IEA Caenorhabditis elegans 17336 R-CFA-2404134 https://reactome.org/PathwayBrowser/#/R-CFA-2404134 RBP4:atROL binds TTR IEA Canis familiaris 17336 R-CFA-2404135 https://reactome.org/PathwayBrowser/#/R-CFA-2404135 RBP4 binds atROL IEA Canis familiaris 17336 R-CFA-2404137 https://reactome.org/PathwayBrowser/#/R-CFA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 17336 R-CFA-2404142 https://reactome.org/PathwayBrowser/#/R-CFA-2404142 atROL binds RBP1 IEA Canis familiaris 17336 R-CFA-2404144 https://reactome.org/PathwayBrowser/#/R-CFA-2404144 Parenchymal atROL translocates to HSCs IEA Canis familiaris 17336 R-CFA-2453855 https://reactome.org/PathwayBrowser/#/R-CFA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 17336 R-CFA-2453863 https://reactome.org/PathwayBrowser/#/R-CFA-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Canis familiaris 17336 R-CFA-2453876 https://reactome.org/PathwayBrowser/#/R-CFA-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Canis familiaris 17336 R-CFA-2464809 https://reactome.org/PathwayBrowser/#/R-CFA-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Canis familiaris 17336 R-CFA-2464822 https://reactome.org/PathwayBrowser/#/R-CFA-2464822 RDH12 reduces atRAL to atROL IEA Canis familiaris 17336 R-CFA-2465938 https://reactome.org/PathwayBrowser/#/R-CFA-2465938 RBP3 regulates atROL taken up by Muller cells IEA Canis familiaris 17336 R-CFA-2465940 https://reactome.org/PathwayBrowser/#/R-CFA-2465940 atRAL is reduced to atROL IEA Canis familiaris 17336 R-CFA-2465971 https://reactome.org/PathwayBrowser/#/R-CFA-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Canis familiaris 17336 R-CFA-2855259 https://reactome.org/PathwayBrowser/#/R-CFA-2855259 atROL binds RBP1 (parenchymal cell) IEA Canis familiaris 17336 R-CFA-5246478 https://reactome.org/PathwayBrowser/#/R-CFA-5246478 APOM binds retinoids IEA Canis familiaris 17336 R-CFA-5362518 https://reactome.org/PathwayBrowser/#/R-CFA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Canis familiaris 17336 R-CFA-5362564 https://reactome.org/PathwayBrowser/#/R-CFA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Canis familiaris 17336 R-CFA-5419165 https://reactome.org/PathwayBrowser/#/R-CFA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Canis familiaris 17336 R-CFA-5623643 https://reactome.org/PathwayBrowser/#/R-CFA-5623643 RDH13 reduces atRAL to atROL IEA Canis familiaris 17336 R-CFA-74843 https://reactome.org/PathwayBrowser/#/R-CFA-74843 atROL binds RBP1 to form RBP1:atROL IEA Canis familiaris 17336 R-CFA-8848355 https://reactome.org/PathwayBrowser/#/R-CFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Canis familiaris 17336 R-CFA-8848585 https://reactome.org/PathwayBrowser/#/R-CFA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Canis familiaris 17336 R-CFA-975594 https://reactome.org/PathwayBrowser/#/R-CFA-975594 PLB1 hydrolyses RPALM to atROL IEA Canis familiaris 17336 R-CFA-975608 https://reactome.org/PathwayBrowser/#/R-CFA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Canis familiaris 17336 R-CFA-975633 https://reactome.org/PathwayBrowser/#/R-CFA-975633 atROL binds to RBP2 IEA Canis familiaris 17336 R-DDI-2465971 https://reactome.org/PathwayBrowser/#/R-DDI-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Dictyostelium discoideum 17336 R-DDI-5362564 https://reactome.org/PathwayBrowser/#/R-DDI-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Dictyostelium discoideum 17336 R-DDI-5419165 https://reactome.org/PathwayBrowser/#/R-DDI-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Dictyostelium discoideum 17336 R-DDI-5615668 https://reactome.org/PathwayBrowser/#/R-DDI-5615668 AKR1C3 reduces atRAL to atROL IEA Dictyostelium discoideum 17336 R-DDI-5623643 https://reactome.org/PathwayBrowser/#/R-DDI-5623643 RDH13 reduces atRAL to atROL IEA Dictyostelium discoideum 17336 R-DDI-8848585 https://reactome.org/PathwayBrowser/#/R-DDI-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Dictyostelium discoideum 17336 R-DME-2404142 https://reactome.org/PathwayBrowser/#/R-DME-2404142 atROL binds RBP1 IEA Drosophila melanogaster 17336 R-DME-2404144 https://reactome.org/PathwayBrowser/#/R-DME-2404144 Parenchymal atROL translocates to HSCs IEA Drosophila melanogaster 17336 R-DME-2464822 https://reactome.org/PathwayBrowser/#/R-DME-2464822 RDH12 reduces atRAL to atROL IEA Drosophila melanogaster 17336 R-DME-2465940 https://reactome.org/PathwayBrowser/#/R-DME-2465940 atRAL is reduced to atROL IEA Drosophila melanogaster 17336 R-DME-2465971 https://reactome.org/PathwayBrowser/#/R-DME-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Drosophila melanogaster 17336 R-DME-2855252 https://reactome.org/PathwayBrowser/#/R-DME-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 17336 R-DME-2855259 https://reactome.org/PathwayBrowser/#/R-DME-2855259 atROL binds RBP1 (parenchymal cell) IEA Drosophila melanogaster 17336 R-DME-5362518 https://reactome.org/PathwayBrowser/#/R-DME-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Drosophila melanogaster 17336 R-DME-5362564 https://reactome.org/PathwayBrowser/#/R-DME-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Drosophila melanogaster 17336 R-DME-5419165 https://reactome.org/PathwayBrowser/#/R-DME-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Drosophila melanogaster 17336 R-DME-5615668 https://reactome.org/PathwayBrowser/#/R-DME-5615668 AKR1C3 reduces atRAL to atROL IEA Drosophila melanogaster 17336 R-DME-74843 https://reactome.org/PathwayBrowser/#/R-DME-74843 atROL binds RBP1 to form RBP1:atROL IEA Drosophila melanogaster 17336 R-DME-8848585 https://reactome.org/PathwayBrowser/#/R-DME-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Drosophila melanogaster 17336 R-DME-975594 https://reactome.org/PathwayBrowser/#/R-DME-975594 PLB1 hydrolyses RPALM to atROL IEA Drosophila melanogaster 17336 R-DME-975629 https://reactome.org/PathwayBrowser/#/R-DME-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 17336 R-DME-975633 https://reactome.org/PathwayBrowser/#/R-DME-975633 atROL binds to RBP2 IEA Drosophila melanogaster 17336 R-DRE-2404135 https://reactome.org/PathwayBrowser/#/R-DRE-2404135 RBP4 binds atROL IEA Danio rerio 17336 R-DRE-2404137 https://reactome.org/PathwayBrowser/#/R-DRE-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 17336 R-DRE-2404142 https://reactome.org/PathwayBrowser/#/R-DRE-2404142 atROL binds RBP1 IEA Danio rerio 17336 R-DRE-2404144 https://reactome.org/PathwayBrowser/#/R-DRE-2404144 Parenchymal atROL translocates to HSCs IEA Danio rerio 17336 R-DRE-2453855 https://reactome.org/PathwayBrowser/#/R-DRE-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 17336 R-DRE-2464822 https://reactome.org/PathwayBrowser/#/R-DRE-2464822 RDH12 reduces atRAL to atROL IEA Danio rerio 17336 R-DRE-2465940 https://reactome.org/PathwayBrowser/#/R-DRE-2465940 atRAL is reduced to atROL IEA Danio rerio 17336 R-DRE-2465971 https://reactome.org/PathwayBrowser/#/R-DRE-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Danio rerio 17336 R-DRE-2855252 https://reactome.org/PathwayBrowser/#/R-DRE-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Danio rerio 17336 R-DRE-2855259 https://reactome.org/PathwayBrowser/#/R-DRE-2855259 atROL binds RBP1 (parenchymal cell) IEA Danio rerio 17336 R-DRE-5362518 https://reactome.org/PathwayBrowser/#/R-DRE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Danio rerio 17336 R-DRE-5362564 https://reactome.org/PathwayBrowser/#/R-DRE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Danio rerio 17336 R-DRE-5419165 https://reactome.org/PathwayBrowser/#/R-DRE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Danio rerio 17336 R-DRE-74843 https://reactome.org/PathwayBrowser/#/R-DRE-74843 atROL binds RBP1 to form RBP1:atROL IEA Danio rerio 17336 R-DRE-8848585 https://reactome.org/PathwayBrowser/#/R-DRE-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Danio rerio 17336 R-DRE-975608 https://reactome.org/PathwayBrowser/#/R-DRE-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Danio rerio 17336 R-DRE-975629 https://reactome.org/PathwayBrowser/#/R-DRE-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Danio rerio 17336 R-DRE-975633 https://reactome.org/PathwayBrowser/#/R-DRE-975633 atROL binds to RBP2 IEA Danio rerio 17336 R-GGA-2404134 https://reactome.org/PathwayBrowser/#/R-GGA-2404134 RBP4:atROL binds TTR IEA Gallus gallus 17336 R-GGA-2404135 https://reactome.org/PathwayBrowser/#/R-GGA-2404135 RBP4 binds atROL IEA Gallus gallus 17336 R-GGA-2404137 https://reactome.org/PathwayBrowser/#/R-GGA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 17336 R-GGA-2404142 https://reactome.org/PathwayBrowser/#/R-GGA-2404142 atROL binds RBP1 IEA Gallus gallus 17336 R-GGA-2404144 https://reactome.org/PathwayBrowser/#/R-GGA-2404144 Parenchymal atROL translocates to HSCs IEA Gallus gallus 17336 R-GGA-2453855 https://reactome.org/PathwayBrowser/#/R-GGA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 17336 R-GGA-2453863 https://reactome.org/PathwayBrowser/#/R-GGA-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Gallus gallus 17336 R-GGA-2453876 https://reactome.org/PathwayBrowser/#/R-GGA-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Gallus gallus 17336 R-GGA-2464809 https://reactome.org/PathwayBrowser/#/R-GGA-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Gallus gallus 17336 R-GGA-2464822 https://reactome.org/PathwayBrowser/#/R-GGA-2464822 RDH12 reduces atRAL to atROL IEA Gallus gallus 17336 R-GGA-2465929 https://reactome.org/PathwayBrowser/#/R-GGA-2465929 Isomerase II isomerises atROL to 11cROL TAS Gallus gallus 17336 R-GGA-2465938 https://reactome.org/PathwayBrowser/#/R-GGA-2465938 RBP3 regulates atROL taken up by Muller cells IEA Gallus gallus 17336 R-GGA-2465940 https://reactome.org/PathwayBrowser/#/R-GGA-2465940 atRAL is reduced to atROL IEA Gallus gallus 17336 R-GGA-2465971 https://reactome.org/PathwayBrowser/#/R-GGA-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Gallus gallus 17336 R-GGA-2855252 https://reactome.org/PathwayBrowser/#/R-GGA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Gallus gallus 17336 R-GGA-2855259 https://reactome.org/PathwayBrowser/#/R-GGA-2855259 atROL binds RBP1 (parenchymal cell) IEA Gallus gallus 17336 R-GGA-5362518 https://reactome.org/PathwayBrowser/#/R-GGA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Gallus gallus 17336 R-GGA-5362564 https://reactome.org/PathwayBrowser/#/R-GGA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Gallus gallus 17336 R-GGA-5419165 https://reactome.org/PathwayBrowser/#/R-GGA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Gallus gallus 17336 R-GGA-74843 https://reactome.org/PathwayBrowser/#/R-GGA-74843 atROL binds RBP1 to form RBP1:atROL IEA Gallus gallus 17336 R-GGA-8848355 https://reactome.org/PathwayBrowser/#/R-GGA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Gallus gallus 17336 R-GGA-8848585 https://reactome.org/PathwayBrowser/#/R-GGA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Gallus gallus 17336 R-GGA-975593 https://reactome.org/PathwayBrowser/#/R-GGA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Gallus gallus 17336 R-GGA-975594 https://reactome.org/PathwayBrowser/#/R-GGA-975594 PLB1 hydrolyses RPALM to atROL IEA Gallus gallus 17336 R-GGA-975608 https://reactome.org/PathwayBrowser/#/R-GGA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Gallus gallus 17336 R-GGA-975629 https://reactome.org/PathwayBrowser/#/R-GGA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Gallus gallus 17336 R-GGA-975633 https://reactome.org/PathwayBrowser/#/R-GGA-975633 atROL binds to RBP2 IEA Gallus gallus 17336 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 17336 R-HSA-2404134 https://reactome.org/PathwayBrowser/#/R-HSA-2404134 RBP4:atROL binds TTR TAS Homo sapiens 17336 R-HSA-2404135 https://reactome.org/PathwayBrowser/#/R-HSA-2404135 RBP4 binds atROL TAS Homo sapiens 17336 R-HSA-2404137 https://reactome.org/PathwayBrowser/#/R-HSA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 17336 R-HSA-2404139 https://reactome.org/PathwayBrowser/#/R-HSA-2404139 HSC cytosolic atROL translocates to extracellular region TAS Homo sapiens 17336 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 17336 R-HSA-2404142 https://reactome.org/PathwayBrowser/#/R-HSA-2404142 atROL binds RBP1 TAS Homo sapiens 17336 R-HSA-2404144 https://reactome.org/PathwayBrowser/#/R-HSA-2404144 Parenchymal atROL translocates to HSCs TAS Homo sapiens 17336 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 17336 R-HSA-2453818 https://reactome.org/PathwayBrowser/#/R-HSA-2453818 Defective STRA6 does not transport atROL TAS Homo sapiens 17336 R-HSA-2453855 https://reactome.org/PathwayBrowser/#/R-HSA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 17336 R-HSA-2453863 https://reactome.org/PathwayBrowser/#/R-HSA-2453863 STRA6 transports atROL from extracellular region to cytosol TAS Homo sapiens 17336 R-HSA-2453876 https://reactome.org/PathwayBrowser/#/R-HSA-2453876 TTR:RBP:atROL binds to STRA6 receptor TAS Homo sapiens 17336 R-HSA-2464803 https://reactome.org/PathwayBrowser/#/R-HSA-2464803 RDH8 reduces atRAL to atROL IEA Homo sapiens 17336 R-HSA-2464809 https://reactome.org/PathwayBrowser/#/R-HSA-2464809 RBP3 regulates the transport of atROL from ROS to RPE TAS Homo sapiens 17336 R-HSA-2464822 https://reactome.org/PathwayBrowser/#/R-HSA-2464822 RDH12 reduces atRAL to atROL TAS Homo sapiens 17336 R-HSA-2465926 https://reactome.org/PathwayBrowser/#/R-HSA-2465926 An atROL isomerase isomerises atROL to 11cROL IEA Homo sapiens 17336 R-HSA-2465938 https://reactome.org/PathwayBrowser/#/R-HSA-2465938 RBP3 regulates atROL taken up by Muller cells TAS Homo sapiens 17336 R-HSA-2465940 https://reactome.org/PathwayBrowser/#/R-HSA-2465940 atRAL is reduced to atROL TAS Homo sapiens 17336 R-HSA-2465971 https://reactome.org/PathwayBrowser/#/R-HSA-2465971 RLBP1 binds atROL to form RLBP1:atROL TAS Homo sapiens 17336 R-HSA-2466710 https://reactome.org/PathwayBrowser/#/R-HSA-2466710 Defective LRAT does not esterify RBP1:atROL and FACYLs to atREs TAS Homo sapiens 17336 R-HSA-2466828 https://reactome.org/PathwayBrowser/#/R-HSA-2466828 Defective RBP4 does not bind atROL TAS Homo sapiens 17336 R-HSA-2855252 https://reactome.org/PathwayBrowser/#/R-HSA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL TAS Homo sapiens 17336 R-HSA-2855259 https://reactome.org/PathwayBrowser/#/R-HSA-2855259 atROL binds RBP1 (parenchymal cell) TAS Homo sapiens 17336 R-HSA-5246478 https://reactome.org/PathwayBrowser/#/R-HSA-5246478 APOM binds retinoids TAS Homo sapiens 17336 R-HSA-5362518 https://reactome.org/PathwayBrowser/#/R-HSA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL TAS Homo sapiens 17336 R-HSA-5362564 https://reactome.org/PathwayBrowser/#/R-HSA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro TAS Homo sapiens 17336 R-HSA-5419165 https://reactome.org/PathwayBrowser/#/R-HSA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL TAS Homo sapiens 17336 R-HSA-5615668 https://reactome.org/PathwayBrowser/#/R-HSA-5615668 AKR1C3 reduces atRAL to atROL TAS Homo sapiens 17336 R-HSA-5623643 https://reactome.org/PathwayBrowser/#/R-HSA-5623643 RDH13 reduces atRAL to atROL TAS Homo sapiens 17336 R-HSA-74843 https://reactome.org/PathwayBrowser/#/R-HSA-74843 atROL binds RBP1 to form RBP1:atROL TAS Homo sapiens 17336 R-HSA-8848355 https://reactome.org/PathwayBrowser/#/R-HSA-8848355 PNPLA4 hydrolyzes retinyl palmitate TAS Homo sapiens 17336 R-HSA-8848585 https://reactome.org/PathwayBrowser/#/R-HSA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM TAS Homo sapiens 17336 R-HSA-8956427 https://reactome.org/PathwayBrowser/#/R-HSA-8956427 RETSAT reduces atROL to at-13,14-dhROL IEA Homo sapiens 17336 R-HSA-975593 https://reactome.org/PathwayBrowser/#/R-HSA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM TAS Homo sapiens 17336 R-HSA-975594 https://reactome.org/PathwayBrowser/#/R-HSA-975594 PLB1 hydrolyses RPALM to atROL TAS Homo sapiens 17336 R-HSA-975608 https://reactome.org/PathwayBrowser/#/R-HSA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs TAS Homo sapiens 17336 R-HSA-975629 https://reactome.org/PathwayBrowser/#/R-HSA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL TAS Homo sapiens 17336 R-HSA-975633 https://reactome.org/PathwayBrowser/#/R-HSA-975633 atROL binds to RBP2 TAS Homo sapiens 17336 R-MMU-2404134 https://reactome.org/PathwayBrowser/#/R-MMU-2404134 RBP4:atROL binds TTR IEA Mus musculus 17336 R-MMU-2404135 https://reactome.org/PathwayBrowser/#/R-MMU-2404135 RBP4 binds atROL IEA Mus musculus 17336 R-MMU-2404137 https://reactome.org/PathwayBrowser/#/R-MMU-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 17336 R-MMU-2404142 https://reactome.org/PathwayBrowser/#/R-MMU-2404142 atROL binds RBP1 IEA Mus musculus 17336 R-MMU-2404144 https://reactome.org/PathwayBrowser/#/R-MMU-2404144 Parenchymal atROL translocates to HSCs IEA Mus musculus 17336 R-MMU-2453855 https://reactome.org/PathwayBrowser/#/R-MMU-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 17336 R-MMU-2453863 https://reactome.org/PathwayBrowser/#/R-MMU-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Mus musculus 17336 R-MMU-2453876 https://reactome.org/PathwayBrowser/#/R-MMU-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Mus musculus 17336 R-MMU-2464809 https://reactome.org/PathwayBrowser/#/R-MMU-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Mus musculus 17336 R-MMU-2464822 https://reactome.org/PathwayBrowser/#/R-MMU-2464822 RDH12 reduces atRAL to atROL IEA Mus musculus 17336 R-MMU-2465938 https://reactome.org/PathwayBrowser/#/R-MMU-2465938 RBP3 regulates atROL taken up by Muller cells IEA Mus musculus 17336 R-MMU-2465940 https://reactome.org/PathwayBrowser/#/R-MMU-2465940 atRAL is reduced to atROL IEA Mus musculus 17336 R-MMU-2465971 https://reactome.org/PathwayBrowser/#/R-MMU-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Mus musculus 17336 R-MMU-2855252 https://reactome.org/PathwayBrowser/#/R-MMU-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Mus musculus 17336 R-MMU-2855259 https://reactome.org/PathwayBrowser/#/R-MMU-2855259 atROL binds RBP1 (parenchymal cell) IEA Mus musculus 17336 R-MMU-5246478 https://reactome.org/PathwayBrowser/#/R-MMU-5246478 APOM binds retinoids IEA Mus musculus 17336 R-MMU-5362518 https://reactome.org/PathwayBrowser/#/R-MMU-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Mus musculus 17336 R-MMU-5362564 https://reactome.org/PathwayBrowser/#/R-MMU-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Mus musculus 17336 R-MMU-5419165 https://reactome.org/PathwayBrowser/#/R-MMU-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Mus musculus 17336 R-MMU-5615668 https://reactome.org/PathwayBrowser/#/R-MMU-5615668 AKR1C3 reduces atRAL to atROL IEA Mus musculus 17336 R-MMU-5623643 https://reactome.org/PathwayBrowser/#/R-MMU-5623643 RDH13 reduces atRAL to atROL IEA Mus musculus 17336 R-MMU-74843 https://reactome.org/PathwayBrowser/#/R-MMU-74843 atROL binds RBP1 to form RBP1:atROL IEA Mus musculus 17336 R-MMU-8848585 https://reactome.org/PathwayBrowser/#/R-MMU-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Mus musculus 17336 R-MMU-8956439 https://reactome.org/PathwayBrowser/#/R-MMU-8956439 Retsat reduces atROL to at-13,14-dhROL TAS Mus musculus 17336 R-MMU-975593 https://reactome.org/PathwayBrowser/#/R-MMU-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Mus musculus 17336 R-MMU-975594 https://reactome.org/PathwayBrowser/#/R-MMU-975594 PLB1 hydrolyses RPALM to atROL IEA Mus musculus 17336 R-MMU-975608 https://reactome.org/PathwayBrowser/#/R-MMU-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Mus musculus 17336 R-MMU-975629 https://reactome.org/PathwayBrowser/#/R-MMU-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Mus musculus 17336 R-MMU-975633 https://reactome.org/PathwayBrowser/#/R-MMU-975633 atROL binds to RBP2 IEA Mus musculus 17336 R-PFA-5623643 https://reactome.org/PathwayBrowser/#/R-PFA-5623643 RDH13 reduces atRAL to atROL IEA Plasmodium falciparum 17336 R-PFA-8848355 https://reactome.org/PathwayBrowser/#/R-PFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Plasmodium falciparum 17336 R-RNO-2404134 https://reactome.org/PathwayBrowser/#/R-RNO-2404134 RBP4:atROL binds TTR IEA Rattus norvegicus 17336 R-RNO-2404135 https://reactome.org/PathwayBrowser/#/R-RNO-2404135 RBP4 binds atROL IEA Rattus norvegicus 17336 R-RNO-2404137 https://reactome.org/PathwayBrowser/#/R-RNO-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 17336 R-RNO-2404142 https://reactome.org/PathwayBrowser/#/R-RNO-2404142 atROL binds RBP1 IEA Rattus norvegicus 17336 R-RNO-2404144 https://reactome.org/PathwayBrowser/#/R-RNO-2404144 Parenchymal atROL translocates to HSCs IEA Rattus norvegicus 17336 R-RNO-2453855 https://reactome.org/PathwayBrowser/#/R-RNO-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 17336 R-RNO-2453863 https://reactome.org/PathwayBrowser/#/R-RNO-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Rattus norvegicus 17336 R-RNO-2453876 https://reactome.org/PathwayBrowser/#/R-RNO-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Rattus norvegicus 17336 R-RNO-2464809 https://reactome.org/PathwayBrowser/#/R-RNO-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Rattus norvegicus 17336 R-RNO-2464822 https://reactome.org/PathwayBrowser/#/R-RNO-2464822 RDH12 reduces atRAL to atROL IEA Rattus norvegicus 17336 R-RNO-2465938 https://reactome.org/PathwayBrowser/#/R-RNO-2465938 RBP3 regulates atROL taken up by Muller cells IEA Rattus norvegicus 17336 R-RNO-2465940 https://reactome.org/PathwayBrowser/#/R-RNO-2465940 atRAL is reduced to atROL IEA Rattus norvegicus 17336 R-RNO-2465971 https://reactome.org/PathwayBrowser/#/R-RNO-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Rattus norvegicus 17336 R-RNO-2855252 https://reactome.org/PathwayBrowser/#/R-RNO-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 17336 R-RNO-2855259 https://reactome.org/PathwayBrowser/#/R-RNO-2855259 atROL binds RBP1 (parenchymal cell) IEA Rattus norvegicus 17336 R-RNO-5246478 https://reactome.org/PathwayBrowser/#/R-RNO-5246478 APOM binds retinoids IEA Rattus norvegicus 17336 R-RNO-5362518 https://reactome.org/PathwayBrowser/#/R-RNO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Rattus norvegicus 17336 R-RNO-5362564 https://reactome.org/PathwayBrowser/#/R-RNO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Rattus norvegicus 17336 R-RNO-5419165 https://reactome.org/PathwayBrowser/#/R-RNO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Rattus norvegicus 17336 R-RNO-5615668 https://reactome.org/PathwayBrowser/#/R-RNO-5615668 AKR1C3 reduces atRAL to atROL IEA Rattus norvegicus 17336 R-RNO-5623643 https://reactome.org/PathwayBrowser/#/R-RNO-5623643 RDH13 reduces atRAL to atROL IEA Rattus norvegicus 17336 R-RNO-74843 https://reactome.org/PathwayBrowser/#/R-RNO-74843 atROL binds RBP1 to form RBP1:atROL IEA Rattus norvegicus 17336 R-RNO-8848355 https://reactome.org/PathwayBrowser/#/R-RNO-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Rattus norvegicus 17336 R-RNO-8848585 https://reactome.org/PathwayBrowser/#/R-RNO-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Rattus norvegicus 17336 R-RNO-975593 https://reactome.org/PathwayBrowser/#/R-RNO-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Rattus norvegicus 17336 R-RNO-975594 https://reactome.org/PathwayBrowser/#/R-RNO-975594 PLB1 hydrolyses RPALM to atROL IEA Rattus norvegicus 17336 R-RNO-975608 https://reactome.org/PathwayBrowser/#/R-RNO-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Rattus norvegicus 17336 R-RNO-975629 https://reactome.org/PathwayBrowser/#/R-RNO-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 17336 R-RNO-975633 https://reactome.org/PathwayBrowser/#/R-RNO-975633 atROL binds to RBP2 IEA Rattus norvegicus 17336 R-SCE-2465940 https://reactome.org/PathwayBrowser/#/R-SCE-2465940 atRAL is reduced to atROL IEA Saccharomyces cerevisiae 17336 R-SCE-5362518 https://reactome.org/PathwayBrowser/#/R-SCE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Saccharomyces cerevisiae 17336 R-SCE-5362564 https://reactome.org/PathwayBrowser/#/R-SCE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Saccharomyces cerevisiae 17336 R-SCE-5419165 https://reactome.org/PathwayBrowser/#/R-SCE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Saccharomyces cerevisiae 17336 R-SCE-5615668 https://reactome.org/PathwayBrowser/#/R-SCE-5615668 AKR1C3 reduces atRAL to atROL IEA Saccharomyces cerevisiae 17336 R-SCE-8848585 https://reactome.org/PathwayBrowser/#/R-SCE-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Saccharomyces cerevisiae 17336 R-SPO-5362518 https://reactome.org/PathwayBrowser/#/R-SPO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Schizosaccharomyces pombe 17336 R-SPO-5362564 https://reactome.org/PathwayBrowser/#/R-SPO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Schizosaccharomyces pombe 17336 R-SPO-5419165 https://reactome.org/PathwayBrowser/#/R-SPO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Schizosaccharomyces pombe 17336 R-SPO-5615668 https://reactome.org/PathwayBrowser/#/R-SPO-5615668 AKR1C3 reduces atRAL to atROL IEA Schizosaccharomyces pombe 17336 R-SPO-8848585 https://reactome.org/PathwayBrowser/#/R-SPO-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Schizosaccharomyces pombe 17336 R-SSC-2404134 https://reactome.org/PathwayBrowser/#/R-SSC-2404134 RBP4:atROL binds TTR IEA Sus scrofa 17336 R-SSC-2404135 https://reactome.org/PathwayBrowser/#/R-SSC-2404135 RBP4 binds atROL IEA Sus scrofa 17336 R-SSC-2404137 https://reactome.org/PathwayBrowser/#/R-SSC-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 17336 R-SSC-2404142 https://reactome.org/PathwayBrowser/#/R-SSC-2404142 atROL binds RBP1 IEA Sus scrofa 17336 R-SSC-2404144 https://reactome.org/PathwayBrowser/#/R-SSC-2404144 Parenchymal atROL translocates to HSCs IEA Sus scrofa 17336 R-SSC-2453855 https://reactome.org/PathwayBrowser/#/R-SSC-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 17336 R-SSC-2453863 https://reactome.org/PathwayBrowser/#/R-SSC-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Sus scrofa 17336 R-SSC-2453876 https://reactome.org/PathwayBrowser/#/R-SSC-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Sus scrofa 17336 R-SSC-2464809 https://reactome.org/PathwayBrowser/#/R-SSC-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Sus scrofa 17336 R-SSC-2464822 https://reactome.org/PathwayBrowser/#/R-SSC-2464822 RDH12 reduces atRAL to atROL IEA Sus scrofa 17336 R-SSC-2465938 https://reactome.org/PathwayBrowser/#/R-SSC-2465938 RBP3 regulates atROL taken up by Muller cells IEA Sus scrofa 17336 R-SSC-2465940 https://reactome.org/PathwayBrowser/#/R-SSC-2465940 atRAL is reduced to atROL IEA Sus scrofa 17336 R-SSC-2465971 https://reactome.org/PathwayBrowser/#/R-SSC-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Sus scrofa 17336 R-SSC-2855252 https://reactome.org/PathwayBrowser/#/R-SSC-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Sus scrofa 17336 R-SSC-2855259 https://reactome.org/PathwayBrowser/#/R-SSC-2855259 atROL binds RBP1 (parenchymal cell) IEA Sus scrofa 17336 R-SSC-5246478 https://reactome.org/PathwayBrowser/#/R-SSC-5246478 APOM binds retinoids IEA Sus scrofa 17336 R-SSC-5362518 https://reactome.org/PathwayBrowser/#/R-SSC-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Sus scrofa 17336 R-SSC-5362564 https://reactome.org/PathwayBrowser/#/R-SSC-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Sus scrofa 17336 R-SSC-5419165 https://reactome.org/PathwayBrowser/#/R-SSC-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Sus scrofa 17336 R-SSC-5615668 https://reactome.org/PathwayBrowser/#/R-SSC-5615668 AKR1C3 reduces atRAL to atROL IEA Sus scrofa 17336 R-SSC-5623643 https://reactome.org/PathwayBrowser/#/R-SSC-5623643 RDH13 reduces atRAL to atROL IEA Sus scrofa 17336 R-SSC-74843 https://reactome.org/PathwayBrowser/#/R-SSC-74843 atROL binds RBP1 to form RBP1:atROL IEA Sus scrofa 17336 R-SSC-8848355 https://reactome.org/PathwayBrowser/#/R-SSC-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Sus scrofa 17336 R-SSC-8848585 https://reactome.org/PathwayBrowser/#/R-SSC-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Sus scrofa 17336 R-SSC-975593 https://reactome.org/PathwayBrowser/#/R-SSC-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Sus scrofa 17336 R-SSC-975594 https://reactome.org/PathwayBrowser/#/R-SSC-975594 PLB1 hydrolyses RPALM to atROL IEA Sus scrofa 17336 R-SSC-975608 https://reactome.org/PathwayBrowser/#/R-SSC-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Sus scrofa 17336 R-SSC-975629 https://reactome.org/PathwayBrowser/#/R-SSC-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Sus scrofa 17336 R-SSC-975633 https://reactome.org/PathwayBrowser/#/R-SSC-975633 atROL binds to RBP2 IEA Sus scrofa 17336 R-XTR-2404134 https://reactome.org/PathwayBrowser/#/R-XTR-2404134 RBP4:atROL binds TTR IEA Xenopus tropicalis 17336 R-XTR-2404135 https://reactome.org/PathwayBrowser/#/R-XTR-2404135 RBP4 binds atROL IEA Xenopus tropicalis 17336 R-XTR-2404137 https://reactome.org/PathwayBrowser/#/R-XTR-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 17336 R-XTR-2404142 https://reactome.org/PathwayBrowser/#/R-XTR-2404142 atROL binds RBP1 IEA Xenopus tropicalis 17336 R-XTR-2404144 https://reactome.org/PathwayBrowser/#/R-XTR-2404144 Parenchymal atROL translocates to HSCs IEA Xenopus tropicalis 17336 R-XTR-2453855 https://reactome.org/PathwayBrowser/#/R-XTR-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 17336 R-XTR-2453863 https://reactome.org/PathwayBrowser/#/R-XTR-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Xenopus tropicalis 17336 R-XTR-2453876 https://reactome.org/PathwayBrowser/#/R-XTR-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Xenopus tropicalis 17336 R-XTR-2464809 https://reactome.org/PathwayBrowser/#/R-XTR-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Xenopus tropicalis 17336 R-XTR-2465938 https://reactome.org/PathwayBrowser/#/R-XTR-2465938 RBP3 regulates atROL taken up by Muller cells IEA Xenopus tropicalis 17336 R-XTR-2465940 https://reactome.org/PathwayBrowser/#/R-XTR-2465940 atRAL is reduced to atROL IEA Xenopus tropicalis 17336 R-XTR-2465971 https://reactome.org/PathwayBrowser/#/R-XTR-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Xenopus tropicalis 17336 R-XTR-2855252 https://reactome.org/PathwayBrowser/#/R-XTR-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Xenopus tropicalis 17336 R-XTR-2855259 https://reactome.org/PathwayBrowser/#/R-XTR-2855259 atROL binds RBP1 (parenchymal cell) IEA Xenopus tropicalis 17336 R-XTR-5246478 https://reactome.org/PathwayBrowser/#/R-XTR-5246478 APOM binds retinoids IEA Xenopus tropicalis 17336 R-XTR-5362518 https://reactome.org/PathwayBrowser/#/R-XTR-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Xenopus tropicalis 17336 R-XTR-5362564 https://reactome.org/PathwayBrowser/#/R-XTR-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Xenopus tropicalis 17336 R-XTR-5419165 https://reactome.org/PathwayBrowser/#/R-XTR-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Xenopus tropicalis 17336 R-XTR-5615668 https://reactome.org/PathwayBrowser/#/R-XTR-5615668 AKR1C3 reduces atRAL to atROL IEA Xenopus tropicalis 17336 R-XTR-5623643 https://reactome.org/PathwayBrowser/#/R-XTR-5623643 RDH13 reduces atRAL to atROL IEA Xenopus tropicalis 17336 R-XTR-74843 https://reactome.org/PathwayBrowser/#/R-XTR-74843 atROL binds RBP1 to form RBP1:atROL IEA Xenopus tropicalis 17336 R-XTR-8848355 https://reactome.org/PathwayBrowser/#/R-XTR-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Xenopus tropicalis 17336 R-XTR-8848585 https://reactome.org/PathwayBrowser/#/R-XTR-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Xenopus tropicalis 17336 R-XTR-975593 https://reactome.org/PathwayBrowser/#/R-XTR-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Xenopus tropicalis 17336 R-XTR-975608 https://reactome.org/PathwayBrowser/#/R-XTR-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Xenopus tropicalis 17336 R-XTR-975633 https://reactome.org/PathwayBrowser/#/R-XTR-975633 atROL binds to RBP2 IEA Xenopus tropicalis 17345 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 17345 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 17345 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 17345 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 17345 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 17345 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 17345 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 17347 R-BTA-193064 https://reactome.org/PathwayBrowser/#/R-BTA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Bos taurus 17347 R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 17347 R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 17347 R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 17347 R-BTA-469659 https://reactome.org/PathwayBrowser/#/R-BTA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Bos taurus 17347 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 17347 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 17347 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 17347 R-BTA-5625717 https://reactome.org/PathwayBrowser/#/R-BTA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Bos taurus 17347 R-BTA-5625738 https://reactome.org/PathwayBrowser/#/R-BTA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Bos taurus 17347 R-BTA-5625745 https://reactome.org/PathwayBrowser/#/R-BTA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Bos taurus 17347 R-BTA-5625774 https://reactome.org/PathwayBrowser/#/R-BTA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Bos taurus 17347 R-BTA-5625784 https://reactome.org/PathwayBrowser/#/R-BTA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Bos taurus 17347 R-BTA-5625796 https://reactome.org/PathwayBrowser/#/R-BTA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Bos taurus 17347 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 17347 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 17347 R-BTA-5625849 https://reactome.org/PathwayBrowser/#/R-BTA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Bos taurus 17347 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 17347 R-BTA-8877902 https://reactome.org/PathwayBrowser/#/R-BTA-8877902 Activated AR binds RUNX2 IEA Bos taurus 17347 R-BTA-9705713 https://reactome.org/PathwayBrowser/#/R-BTA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Bos taurus 17347 R-BTA-9705714 https://reactome.org/PathwayBrowser/#/R-BTA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Bos taurus 17347 R-BTA-9705925 https://reactome.org/PathwayBrowser/#/R-BTA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Bos taurus 17347 R-CEL-193064 https://reactome.org/PathwayBrowser/#/R-CEL-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Caenorhabditis elegans 17347 R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 17347 R-CEL-469659 https://reactome.org/PathwayBrowser/#/R-CEL-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 17347 R-CEL-9705713 https://reactome.org/PathwayBrowser/#/R-CEL-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 17347 R-CEL-9705714 https://reactome.org/PathwayBrowser/#/R-CEL-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 17347 R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 17347 R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 17347 R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 17347 R-CFA-469659 https://reactome.org/PathwayBrowser/#/R-CFA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Canis familiaris 17347 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 17347 R-CFA-5625717 https://reactome.org/PathwayBrowser/#/R-CFA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Canis familiaris 17347 R-CFA-5625738 https://reactome.org/PathwayBrowser/#/R-CFA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Canis familiaris 17347 R-CFA-5625745 https://reactome.org/PathwayBrowser/#/R-CFA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Canis familiaris 17347 R-CFA-5625774 https://reactome.org/PathwayBrowser/#/R-CFA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Canis familiaris 17347 R-CFA-5625784 https://reactome.org/PathwayBrowser/#/R-CFA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Canis familiaris 17347 R-CFA-5625796 https://reactome.org/PathwayBrowser/#/R-CFA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Canis familiaris 17347 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 17347 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 17347 R-CFA-5625849 https://reactome.org/PathwayBrowser/#/R-CFA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Canis familiaris 17347 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 17347 R-CFA-8877902 https://reactome.org/PathwayBrowser/#/R-CFA-8877902 Activated AR binds RUNX2 IEA Canis familiaris 17347 R-CFA-9705713 https://reactome.org/PathwayBrowser/#/R-CFA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Canis familiaris 17347 R-CFA-9705714 https://reactome.org/PathwayBrowser/#/R-CFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Canis familiaris 17347 R-CFA-9705925 https://reactome.org/PathwayBrowser/#/R-CFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Canis familiaris 17347 R-DDI-193064 https://reactome.org/PathwayBrowser/#/R-DDI-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Dictyostelium discoideum 17347 R-DDI-5625784 https://reactome.org/PathwayBrowser/#/R-DDI-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Dictyostelium discoideum 17347 R-DDI-9705714 https://reactome.org/PathwayBrowser/#/R-DDI-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Dictyostelium discoideum 17347 R-DME-193064 https://reactome.org/PathwayBrowser/#/R-DME-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Drosophila melanogaster 17347 R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 17347 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 17347 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 17347 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 17347 R-DME-5625717 https://reactome.org/PathwayBrowser/#/R-DME-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Drosophila melanogaster 17347 R-DME-5625738 https://reactome.org/PathwayBrowser/#/R-DME-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Drosophila melanogaster 17347 R-DME-5625745 https://reactome.org/PathwayBrowser/#/R-DME-5625745 PKN1 stimulates association of AR with NCOA2 IEA Drosophila melanogaster 17347 R-DME-5625774 https://reactome.org/PathwayBrowser/#/R-DME-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Drosophila melanogaster 17347 R-DME-5625784 https://reactome.org/PathwayBrowser/#/R-DME-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Drosophila melanogaster 17347 R-DME-5625796 https://reactome.org/PathwayBrowser/#/R-DME-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 17347 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 17347 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 17347 R-DME-5625849 https://reactome.org/PathwayBrowser/#/R-DME-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 17347 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 17347 R-DME-8877902 https://reactome.org/PathwayBrowser/#/R-DME-8877902 Activated AR binds RUNX2 IEA Drosophila melanogaster 17347 R-DME-9705714 https://reactome.org/PathwayBrowser/#/R-DME-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Drosophila melanogaster 17347 R-DME-9705925 https://reactome.org/PathwayBrowser/#/R-DME-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Drosophila melanogaster 17347 R-DRE-193064 https://reactome.org/PathwayBrowser/#/R-DRE-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Danio rerio 17347 R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 17347 R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 17347 R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 17347 R-DRE-469659 https://reactome.org/PathwayBrowser/#/R-DRE-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Danio rerio 17347 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 17347 R-DRE-5625717 https://reactome.org/PathwayBrowser/#/R-DRE-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Danio rerio 17347 R-DRE-5625738 https://reactome.org/PathwayBrowser/#/R-DRE-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Danio rerio 17347 R-DRE-5625745 https://reactome.org/PathwayBrowser/#/R-DRE-5625745 PKN1 stimulates association of AR with NCOA2 IEA Danio rerio 17347 R-DRE-5625774 https://reactome.org/PathwayBrowser/#/R-DRE-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Danio rerio 17347 R-DRE-5625784 https://reactome.org/PathwayBrowser/#/R-DRE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Danio rerio 17347 R-DRE-5625796 https://reactome.org/PathwayBrowser/#/R-DRE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Danio rerio 17347 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 17347 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 17347 R-DRE-8877902 https://reactome.org/PathwayBrowser/#/R-DRE-8877902 Activated AR binds RUNX2 IEA Danio rerio 17347 R-DRE-9705713 https://reactome.org/PathwayBrowser/#/R-DRE-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Danio rerio 17347 R-DRE-9705714 https://reactome.org/PathwayBrowser/#/R-DRE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Danio rerio 17347 R-DRE-9705925 https://reactome.org/PathwayBrowser/#/R-DRE-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Danio rerio 17347 R-GGA-193064 https://reactome.org/PathwayBrowser/#/R-GGA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Gallus gallus 17347 R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 17347 R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 17347 R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 17347 R-GGA-469659 https://reactome.org/PathwayBrowser/#/R-GGA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Gallus gallus 17347 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 17347 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 17347 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 17347 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus 17347 R-GGA-5625796 https://reactome.org/PathwayBrowser/#/R-GGA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Gallus gallus 17347 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 17347 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 17347 R-GGA-5625849 https://reactome.org/PathwayBrowser/#/R-GGA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Gallus gallus 17347 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 17347 R-GGA-8877902 https://reactome.org/PathwayBrowser/#/R-GGA-8877902 Activated AR binds RUNX2 IEA Gallus gallus 17347 R-GGA-9705713 https://reactome.org/PathwayBrowser/#/R-GGA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Gallus gallus 17347 R-GGA-9705714 https://reactome.org/PathwayBrowser/#/R-GGA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Gallus gallus 17347 R-GGA-9705925 https://reactome.org/PathwayBrowser/#/R-GGA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Gallus gallus 17347 R-HSA-193064 https://reactome.org/PathwayBrowser/#/R-HSA-193064 HSD17B3-like proteins reducde ANDST to TEST TAS Homo sapiens 17347 R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 17347 R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 17347 R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 17347 R-HSA-469659 https://reactome.org/PathwayBrowser/#/R-HSA-469659 SRD5A1 dehydrogenates TEST to DHTEST TAS Homo sapiens 17347 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 17347 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 17347 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 17347 R-HSA-5625717 https://reactome.org/PathwayBrowser/#/R-HSA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) TAS Homo sapiens 17347 R-HSA-5625738 https://reactome.org/PathwayBrowser/#/R-HSA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus TAS Homo sapiens 17347 R-HSA-5625745 https://reactome.org/PathwayBrowser/#/R-HSA-5625745 PKN1 stimulates association of AR with NCOA2 TAS Homo sapiens 17347 R-HSA-5625774 https://reactome.org/PathwayBrowser/#/R-HSA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes TAS Homo sapiens 17347 R-HSA-5625784 https://reactome.org/PathwayBrowser/#/R-HSA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters TAS Homo sapiens 17347 R-HSA-5625796 https://reactome.org/PathwayBrowser/#/R-HSA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters TAS Homo sapiens 17347 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 17347 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 17347 R-HSA-5625849 https://reactome.org/PathwayBrowser/#/R-HSA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters TAS Homo sapiens 17347 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 17347 R-HSA-5625883 https://reactome.org/PathwayBrowser/#/R-HSA-5625883 PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 TAS Homo sapiens 17347 R-HSA-8877902 https://reactome.org/PathwayBrowser/#/R-HSA-8877902 Activated AR binds RUNX2 TAS Homo sapiens 17347 R-HSA-8877918 https://reactome.org/PathwayBrowser/#/R-HSA-8877918 RUNX2:MAF complex binds the BGLAP gene promoter IEA Homo sapiens 17347 R-HSA-9705713 https://reactome.org/PathwayBrowser/#/R-HSA-9705713 SRD5A2 dehydrogenates TEST to DHTEST TAS Homo sapiens 17347 R-HSA-9705714 https://reactome.org/PathwayBrowser/#/R-HSA-9705714 SRD5A3 dehydrogenates TEST to DHTEST TAS Homo sapiens 17347 R-HSA-9705925 https://reactome.org/PathwayBrowser/#/R-HSA-9705925 Androgens binds AR (in the HSP90 chaperone complex) TAS Homo sapiens 17347 R-MMU-193064 https://reactome.org/PathwayBrowser/#/R-MMU-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Mus musculus 17347 R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 17347 R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 17347 R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 17347 R-MMU-469659 https://reactome.org/PathwayBrowser/#/R-MMU-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Mus musculus 17347 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 17347 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 17347 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 17347 R-MMU-5625717 https://reactome.org/PathwayBrowser/#/R-MMU-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Mus musculus 17347 R-MMU-5625738 https://reactome.org/PathwayBrowser/#/R-MMU-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Mus musculus 17347 R-MMU-5625745 https://reactome.org/PathwayBrowser/#/R-MMU-5625745 PKN1 stimulates association of AR with NCOA2 IEA Mus musculus 17347 R-MMU-8877902 https://reactome.org/PathwayBrowser/#/R-MMU-8877902 Activated AR binds RUNX2 IEA Mus musculus 17347 R-MMU-9705713 https://reactome.org/PathwayBrowser/#/R-MMU-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Mus musculus 17347 R-MMU-9705714 https://reactome.org/PathwayBrowser/#/R-MMU-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Mus musculus 17347 R-MMU-9705925 https://reactome.org/PathwayBrowser/#/R-MMU-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Mus musculus 17347 R-PFA-193064 https://reactome.org/PathwayBrowser/#/R-PFA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Plasmodium falciparum 17347 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 17347 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 17347 R-PFA-9705714 https://reactome.org/PathwayBrowser/#/R-PFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Plasmodium falciparum 17347 R-PFA-9705925 https://reactome.org/PathwayBrowser/#/R-PFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Plasmodium falciparum 17347 R-RNO-193064 https://reactome.org/PathwayBrowser/#/R-RNO-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Rattus norvegicus 17347 R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 17347 R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 17347 R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 17347 R-RNO-469659 https://reactome.org/PathwayBrowser/#/R-RNO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 17347 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 17347 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 17347 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 17347 R-RNO-5625717 https://reactome.org/PathwayBrowser/#/R-RNO-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Rattus norvegicus 17347 R-RNO-5625738 https://reactome.org/PathwayBrowser/#/R-RNO-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Rattus norvegicus 17347 R-RNO-5625745 https://reactome.org/PathwayBrowser/#/R-RNO-5625745 PKN1 stimulates association of AR with NCOA2 IEA Rattus norvegicus 17347 R-RNO-5625774 https://reactome.org/PathwayBrowser/#/R-RNO-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Rattus norvegicus 17347 R-RNO-5625784 https://reactome.org/PathwayBrowser/#/R-RNO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Rattus norvegicus 17347 R-RNO-5625796 https://reactome.org/PathwayBrowser/#/R-RNO-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Rattus norvegicus 17347 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 17347 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 17347 R-RNO-5625849 https://reactome.org/PathwayBrowser/#/R-RNO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Rattus norvegicus 17347 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 17347 R-RNO-9705713 https://reactome.org/PathwayBrowser/#/R-RNO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 17347 R-RNO-9705714 https://reactome.org/PathwayBrowser/#/R-RNO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 17347 R-RNO-9705925 https://reactome.org/PathwayBrowser/#/R-RNO-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Rattus norvegicus 17347 R-SCE-5625784 https://reactome.org/PathwayBrowser/#/R-SCE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 17347 R-SCE-5625796 https://reactome.org/PathwayBrowser/#/R-SCE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 17347 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 17347 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 17347 R-SCE-5625849 https://reactome.org/PathwayBrowser/#/R-SCE-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 17347 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 17347 R-SCE-9705714 https://reactome.org/PathwayBrowser/#/R-SCE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Saccharomyces cerevisiae 17347 R-SPO-469659 https://reactome.org/PathwayBrowser/#/R-SPO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 17347 R-SPO-5625784 https://reactome.org/PathwayBrowser/#/R-SPO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 17347 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 17347 R-SPO-5625849 https://reactome.org/PathwayBrowser/#/R-SPO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 17347 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 17347 R-SPO-9705713 https://reactome.org/PathwayBrowser/#/R-SPO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 17347 R-SPO-9705714 https://reactome.org/PathwayBrowser/#/R-SPO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 17347 R-SSC-193064 https://reactome.org/PathwayBrowser/#/R-SSC-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Sus scrofa 17347 R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 17347 R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 17347 R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 17347 R-SSC-469659 https://reactome.org/PathwayBrowser/#/R-SSC-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Sus scrofa 17347 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 17347 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 17347 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 17347 R-SSC-5625717 https://reactome.org/PathwayBrowser/#/R-SSC-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Sus scrofa 17347 R-SSC-5625738 https://reactome.org/PathwayBrowser/#/R-SSC-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Sus scrofa 17347 R-SSC-5625745 https://reactome.org/PathwayBrowser/#/R-SSC-5625745 PKN1 stimulates association of AR with NCOA2 IEA Sus scrofa 17347 R-SSC-5625774 https://reactome.org/PathwayBrowser/#/R-SSC-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Sus scrofa 17347 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa 17347 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa 17347 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 17347 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 17347 R-SSC-5625849 https://reactome.org/PathwayBrowser/#/R-SSC-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Sus scrofa 17347 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 17347 R-SSC-8877902 https://reactome.org/PathwayBrowser/#/R-SSC-8877902 Activated AR binds RUNX2 IEA Sus scrofa 17347 R-SSC-9705713 https://reactome.org/PathwayBrowser/#/R-SSC-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Sus scrofa 17347 R-SSC-9705714 https://reactome.org/PathwayBrowser/#/R-SSC-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Sus scrofa 17347 R-SSC-9705925 https://reactome.org/PathwayBrowser/#/R-SSC-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Sus scrofa 17347 R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 17347 R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 17347 R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 17347 R-XTR-469659 https://reactome.org/PathwayBrowser/#/R-XTR-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 17347 R-XTR-8877902 https://reactome.org/PathwayBrowser/#/R-XTR-8877902 Activated AR binds RUNX2 IEA Xenopus tropicalis 17347 R-XTR-9705713 https://reactome.org/PathwayBrowser/#/R-XTR-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 17347 R-XTR-9705714 https://reactome.org/PathwayBrowser/#/R-XTR-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 17347 R-XTR-9705925 https://reactome.org/PathwayBrowser/#/R-XTR-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Xenopus tropicalis 17351 R-BTA-2046098 https://reactome.org/PathwayBrowser/#/R-BTA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Bos taurus 17351 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 17351 R-BTA-400143 https://reactome.org/PathwayBrowser/#/R-BTA-400143 Fatty acid ligands activate PPARA IEA Bos taurus 17351 R-BTA-879585 https://reactome.org/PathwayBrowser/#/R-BTA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Bos taurus 17351 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 17351 R-CEL-879585 https://reactome.org/PathwayBrowser/#/R-CEL-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Caenorhabditis elegans 17351 R-CFA-2046098 https://reactome.org/PathwayBrowser/#/R-CFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Canis familiaris 17351 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 17351 R-CFA-400143 https://reactome.org/PathwayBrowser/#/R-CFA-400143 Fatty acid ligands activate PPARA IEA Canis familiaris 17351 R-CFA-879585 https://reactome.org/PathwayBrowser/#/R-CFA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Canis familiaris 17351 R-DDI-2046098 https://reactome.org/PathwayBrowser/#/R-DDI-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Dictyostelium discoideum 17351 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 17351 R-DME-400143 https://reactome.org/PathwayBrowser/#/R-DME-400143 Fatty acid ligands activate PPARA IEA Drosophila melanogaster 17351 R-DME-879585 https://reactome.org/PathwayBrowser/#/R-DME-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Drosophila melanogaster 17351 R-DRE-2046098 https://reactome.org/PathwayBrowser/#/R-DRE-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Danio rerio 17351 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 17351 R-DRE-400143 https://reactome.org/PathwayBrowser/#/R-DRE-400143 Fatty acid ligands activate PPARA IEA Danio rerio 17351 R-DRE-879585 https://reactome.org/PathwayBrowser/#/R-DRE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Danio rerio 17351 R-GGA-2046098 https://reactome.org/PathwayBrowser/#/R-GGA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Gallus gallus 17351 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 17351 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus 17351 R-GGA-879585 https://reactome.org/PathwayBrowser/#/R-GGA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Gallus gallus 17351 R-HSA-1368065 https://reactome.org/PathwayBrowser/#/R-HSA-1368065 Expression of NPAS2 IEA Homo sapiens 17351 R-HSA-1592238 https://reactome.org/PathwayBrowser/#/R-HSA-1592238 Expression of ALAS1 TAS Homo sapiens 17351 R-HSA-1655826 https://reactome.org/PathwayBrowser/#/R-HSA-1655826 Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) TAS Homo sapiens 17351 R-HSA-1655848 https://reactome.org/PathwayBrowser/#/R-HSA-1655848 Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) TAS Homo sapiens 17351 R-HSA-1655850 https://reactome.org/PathwayBrowser/#/R-HSA-1655850 Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) TAS Homo sapiens 17351 R-HSA-1801587 https://reactome.org/PathwayBrowser/#/R-HSA-1801587 Expression of CPT1A IEA Homo sapiens 17351 R-HSA-1989745 https://reactome.org/PathwayBrowser/#/R-HSA-1989745 Expression of ACADM TAS Homo sapiens 17351 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 17351 R-HSA-1989747 https://reactome.org/PathwayBrowser/#/R-HSA-1989747 Expression of FHL2 TAS Homo sapiens 17351 R-HSA-1989748 https://reactome.org/PathwayBrowser/#/R-HSA-1989748 Expression of GRHL1 TAS Homo sapiens 17351 R-HSA-1989749 https://reactome.org/PathwayBrowser/#/R-HSA-1989749 Expression of ACOX1 TAS Homo sapiens 17351 R-HSA-1989750 https://reactome.org/PathwayBrowser/#/R-HSA-1989750 Expression of FATP1 (SLC27A1) TAS Homo sapiens 17351 R-HSA-1989751 https://reactome.org/PathwayBrowser/#/R-HSA-1989751 Expression of FABP1 TAS Homo sapiens 17351 R-HSA-1989752 https://reactome.org/PathwayBrowser/#/R-HSA-1989752 Expression of TXNRD1 TAS Homo sapiens 17351 R-HSA-1989753 https://reactome.org/PathwayBrowser/#/R-HSA-1989753 Expression of PEX11A TAS Homo sapiens 17351 R-HSA-1989754 https://reactome.org/PathwayBrowser/#/R-HSA-1989754 Expression of APOA1 TAS Homo sapiens 17351 R-HSA-1989755 https://reactome.org/PathwayBrowser/#/R-HSA-1989755 Expression of CYP4A11 TAS Homo sapiens 17351 R-HSA-1989756 https://reactome.org/PathwayBrowser/#/R-HSA-1989756 Expression of ME1 TAS Homo sapiens 17351 R-HSA-1989757 https://reactome.org/PathwayBrowser/#/R-HSA-1989757 Expression of FADS1 TAS Homo sapiens 17351 R-HSA-1989758 https://reactome.org/PathwayBrowser/#/R-HSA-1989758 Expression of UGT1A9 TAS Homo sapiens 17351 R-HSA-1989759 https://reactome.org/PathwayBrowser/#/R-HSA-1989759 Expression of G0S2 TAS Homo sapiens 17351 R-HSA-1989760 https://reactome.org/PathwayBrowser/#/R-HSA-1989760 Expression of HMGCS2 TAS Homo sapiens 17351 R-HSA-1989761 https://reactome.org/PathwayBrowser/#/R-HSA-1989761 Expression of APOA5 TAS Homo sapiens 17351 R-HSA-1989762 https://reactome.org/PathwayBrowser/#/R-HSA-1989762 Expression of ABCB4 TAS Homo sapiens 17351 R-HSA-1989764 https://reactome.org/PathwayBrowser/#/R-HSA-1989764 Expression of CYP1A1 TAS Homo sapiens 17351 R-HSA-1989765 https://reactome.org/PathwayBrowser/#/R-HSA-1989765 Expression of ABCA1 TAS Homo sapiens 17351 R-HSA-1989767 https://reactome.org/PathwayBrowser/#/R-HSA-1989767 Expression of TRIB3 TAS Homo sapiens 17351 R-HSA-1989768 https://reactome.org/PathwayBrowser/#/R-HSA-1989768 Expression of TIAM2 TAS Homo sapiens 17351 R-HSA-1989770 https://reactome.org/PathwayBrowser/#/R-HSA-1989770 Expression of PLIN2 TAS Homo sapiens 17351 R-HSA-1989771 https://reactome.org/PathwayBrowser/#/R-HSA-1989771 Expression of TNFRSF21 TAS Homo sapiens 17351 R-HSA-1989772 https://reactome.org/PathwayBrowser/#/R-HSA-1989772 Expression of GLIPR1 TAS Homo sapiens 17351 R-HSA-1989773 https://reactome.org/PathwayBrowser/#/R-HSA-1989773 Expression of CPT2 TAS Homo sapiens 17351 R-HSA-1989774 https://reactome.org/PathwayBrowser/#/R-HSA-1989774 Expression of AGT TAS Homo sapiens 17351 R-HSA-1989775 https://reactome.org/PathwayBrowser/#/R-HSA-1989775 Expression of SULT2A1 TAS Homo sapiens 17351 R-HSA-1989776 https://reactome.org/PathwayBrowser/#/R-HSA-1989776 Expression of APOA2 TAS Homo sapiens 17351 R-HSA-1989777 https://reactome.org/PathwayBrowser/#/R-HSA-1989777 Expression of RGL1 TAS Homo sapiens 17351 R-HSA-1989778 https://reactome.org/PathwayBrowser/#/R-HSA-1989778 Expression of ACSL1 TAS Homo sapiens 17351 R-HSA-1989779 https://reactome.org/PathwayBrowser/#/R-HSA-1989779 Expression of ANKRD1 TAS Homo sapiens 17351 R-HSA-2046098 https://reactome.org/PathwayBrowser/#/R-HSA-2046098 Activation of linoleic acid to linoleoyl-CoA TAS Homo sapiens 17351 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 17351 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 17351 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 17351 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 17351 R-HSA-400143 https://reactome.org/PathwayBrowser/#/R-HSA-400143 Fatty acid ligands activate PPARA TAS Homo sapiens 17351 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 17351 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 17351 R-HSA-5627891 https://reactome.org/PathwayBrowser/#/R-HSA-5627891 Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol TAS Homo sapiens 17351 R-HSA-879585 https://reactome.org/PathwayBrowser/#/R-HSA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol TAS Homo sapiens 17351 R-HSA-879724 https://reactome.org/PathwayBrowser/#/R-HSA-879724 Expression of PPARA IEA Homo sapiens 17351 R-MMU-2046098 https://reactome.org/PathwayBrowser/#/R-MMU-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Mus musculus 17351 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 17351 R-MMU-400143 https://reactome.org/PathwayBrowser/#/R-MMU-400143 Fatty acid ligands activate PPARA IEA Mus musculus 17351 R-MMU-879585 https://reactome.org/PathwayBrowser/#/R-MMU-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Mus musculus 17351 R-PFA-2046098 https://reactome.org/PathwayBrowser/#/R-PFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Plasmodium falciparum 17351 R-RNO-2046098 https://reactome.org/PathwayBrowser/#/R-RNO-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Rattus norvegicus 17351 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 17351 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus 17351 R-RNO-879585 https://reactome.org/PathwayBrowser/#/R-RNO-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Rattus norvegicus 17351 R-SCE-879585 https://reactome.org/PathwayBrowser/#/R-SCE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Saccharomyces cerevisiae 17351 R-SSC-2046098 https://reactome.org/PathwayBrowser/#/R-SSC-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Sus scrofa 17351 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 17351 R-SSC-879585 https://reactome.org/PathwayBrowser/#/R-SSC-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Sus scrofa 17351 R-XTR-2046098 https://reactome.org/PathwayBrowser/#/R-XTR-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Xenopus tropicalis 17351 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 17351 R-XTR-879585 https://reactome.org/PathwayBrowser/#/R-XTR-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Xenopus tropicalis 173517 R-BTA-9753280 https://reactome.org/PathwayBrowser/#/R-BTA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Bos taurus 173517 R-BTA-9753285 https://reactome.org/PathwayBrowser/#/R-BTA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Bos taurus 173517 R-CEL-9753280 https://reactome.org/PathwayBrowser/#/R-CEL-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Caenorhabditis elegans 173517 R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans 173517 R-CFA-9753280 https://reactome.org/PathwayBrowser/#/R-CFA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Canis familiaris 173517 R-CFA-9753285 https://reactome.org/PathwayBrowser/#/R-CFA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Canis familiaris 173517 R-DDI-9753280 https://reactome.org/PathwayBrowser/#/R-DDI-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Dictyostelium discoideum 173517 R-DDI-9753285 https://reactome.org/PathwayBrowser/#/R-DDI-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Dictyostelium discoideum 173517 R-DME-9753280 https://reactome.org/PathwayBrowser/#/R-DME-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Drosophila melanogaster 173517 R-DME-9753285 https://reactome.org/PathwayBrowser/#/R-DME-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Drosophila melanogaster 173517 R-DRE-9753280 https://reactome.org/PathwayBrowser/#/R-DRE-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Danio rerio 173517 R-DRE-9753285 https://reactome.org/PathwayBrowser/#/R-DRE-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Danio rerio 173517 R-GGA-9753280 https://reactome.org/PathwayBrowser/#/R-GGA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Gallus gallus 173517 R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus 173517 R-HSA-9753280 https://reactome.org/PathwayBrowser/#/R-HSA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG TAS Homo sapiens 173517 R-HSA-9753285 https://reactome.org/PathwayBrowser/#/R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI TAS Homo sapiens 173517 R-HSA-9753916 https://reactome.org/PathwayBrowser/#/R-HSA-9753916 NAPQI binds proteins in hepatocytes TAS Homo sapiens 173517 R-MMU-9753280 https://reactome.org/PathwayBrowser/#/R-MMU-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Mus musculus 173517 R-MMU-9753285 https://reactome.org/PathwayBrowser/#/R-MMU-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Mus musculus 173517 R-PFA-9753280 https://reactome.org/PathwayBrowser/#/R-PFA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Plasmodium falciparum 173517 R-RNO-9753280 https://reactome.org/PathwayBrowser/#/R-RNO-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Rattus norvegicus 173517 R-RNO-9753285 https://reactome.org/PathwayBrowser/#/R-RNO-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Rattus norvegicus 173517 R-SSC-9753280 https://reactome.org/PathwayBrowser/#/R-SSC-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Sus scrofa 173517 R-SSC-9753285 https://reactome.org/PathwayBrowser/#/R-SSC-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Sus scrofa 173517 R-XTR-9753280 https://reactome.org/PathwayBrowser/#/R-XTR-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Xenopus tropicalis 173517 R-XTR-9753285 https://reactome.org/PathwayBrowser/#/R-XTR-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Xenopus tropicalis 17359 R-BTA-1614544 https://reactome.org/PathwayBrowser/#/R-BTA-1614544 Sulfite is oxidized to sulfate IEA Bos taurus 17359 R-BTA-1614605 https://reactome.org/PathwayBrowser/#/R-BTA-1614605 Persulfide sulfur is dioxygenated IEA Bos taurus 17359 R-BTA-1655879 https://reactome.org/PathwayBrowser/#/R-BTA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Bos taurus 17359 R-BTA-9013198 https://reactome.org/PathwayBrowser/#/R-BTA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Bos taurus 17359 R-CEL-1614544 https://reactome.org/PathwayBrowser/#/R-CEL-1614544 Sulfite is oxidized to sulfate IEA Caenorhabditis elegans 17359 R-CEL-1614605 https://reactome.org/PathwayBrowser/#/R-CEL-1614605 Persulfide sulfur is dioxygenated IEA Caenorhabditis elegans 17359 R-CEL-9013198 https://reactome.org/PathwayBrowser/#/R-CEL-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Caenorhabditis elegans 17359 R-CFA-1614544 https://reactome.org/PathwayBrowser/#/R-CFA-1614544 Sulfite is oxidized to sulfate IEA Canis familiaris 17359 R-CFA-1614605 https://reactome.org/PathwayBrowser/#/R-CFA-1614605 Persulfide sulfur is dioxygenated IEA Canis familiaris 17359 R-CFA-1655879 https://reactome.org/PathwayBrowser/#/R-CFA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Canis familiaris 17359 R-CFA-9013198 https://reactome.org/PathwayBrowser/#/R-CFA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Canis familiaris 17359 R-DDI-1614544 https://reactome.org/PathwayBrowser/#/R-DDI-1614544 Sulfite is oxidized to sulfate IEA Dictyostelium discoideum 17359 R-DDI-9013198 https://reactome.org/PathwayBrowser/#/R-DDI-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Dictyostelium discoideum 17359 R-DME-1614544 https://reactome.org/PathwayBrowser/#/R-DME-1614544 Sulfite is oxidized to sulfate IEA Drosophila melanogaster 17359 R-DME-1614605 https://reactome.org/PathwayBrowser/#/R-DME-1614605 Persulfide sulfur is dioxygenated IEA Drosophila melanogaster 17359 R-DRE-1614605 https://reactome.org/PathwayBrowser/#/R-DRE-1614605 Persulfide sulfur is dioxygenated IEA Danio rerio 17359 R-DRE-9013198 https://reactome.org/PathwayBrowser/#/R-DRE-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Danio rerio 17359 R-GGA-1614544 https://reactome.org/PathwayBrowser/#/R-GGA-1614544 Sulfite is oxidized to sulfate IEA Gallus gallus 17359 R-GGA-9013198 https://reactome.org/PathwayBrowser/#/R-GGA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Gallus gallus 17359 R-HSA-1614544 https://reactome.org/PathwayBrowser/#/R-HSA-1614544 Sulfite is oxidized to sulfate TAS Homo sapiens 17359 R-HSA-1614605 https://reactome.org/PathwayBrowser/#/R-HSA-1614605 Persulfide sulfur is dioxygenated TAS Homo sapiens 17359 R-HSA-1614618 https://reactome.org/PathwayBrowser/#/R-HSA-1614618 Persulfide sulfur is transferred onto sulfite IEA Homo sapiens 17359 R-HSA-1655879 https://reactome.org/PathwayBrowser/#/R-HSA-1655879 Thiosulfate can transfer its sulfur atom to glutathione TAS Homo sapiens 17359 R-HSA-9013198 https://reactome.org/PathwayBrowser/#/R-HSA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN TAS Homo sapiens 17359 R-MMU-1614544 https://reactome.org/PathwayBrowser/#/R-MMU-1614544 Sulfite is oxidized to sulfate IEA Mus musculus 17359 R-MMU-1614605 https://reactome.org/PathwayBrowser/#/R-MMU-1614605 Persulfide sulfur is dioxygenated IEA Mus musculus 17359 R-MMU-1655879 https://reactome.org/PathwayBrowser/#/R-MMU-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Mus musculus 17359 R-MMU-9013198 https://reactome.org/PathwayBrowser/#/R-MMU-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Mus musculus 17359 R-PFA-9013198 https://reactome.org/PathwayBrowser/#/R-PFA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Plasmodium falciparum 17359 R-RNO-1614544 https://reactome.org/PathwayBrowser/#/R-RNO-1614544 Sulfite is oxidized to sulfate IEA Rattus norvegicus 17359 R-RNO-1614605 https://reactome.org/PathwayBrowser/#/R-RNO-1614605 Persulfide sulfur is dioxygenated IEA Rattus norvegicus 17359 R-RNO-1614611 https://reactome.org/PathwayBrowser/#/R-RNO-1614611 Persulfide sulfur is transferred onto sulfite TAS Rattus norvegicus 17359 R-RNO-1655879 https://reactome.org/PathwayBrowser/#/R-RNO-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Rattus norvegicus 17359 R-RNO-9013198 https://reactome.org/PathwayBrowser/#/R-RNO-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Rattus norvegicus 17359 R-SCE-9013198 https://reactome.org/PathwayBrowser/#/R-SCE-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Saccharomyces cerevisiae 17359 R-SPO-9013198 https://reactome.org/PathwayBrowser/#/R-SPO-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Schizosaccharomyces pombe 17359 R-SSC-1614544 https://reactome.org/PathwayBrowser/#/R-SSC-1614544 Sulfite is oxidized to sulfate IEA Sus scrofa 17359 R-SSC-1614605 https://reactome.org/PathwayBrowser/#/R-SSC-1614605 Persulfide sulfur is dioxygenated IEA Sus scrofa 17359 R-SSC-1655879 https://reactome.org/PathwayBrowser/#/R-SSC-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Sus scrofa 17359 R-SSC-9013198 https://reactome.org/PathwayBrowser/#/R-SSC-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Sus scrofa 17359 R-XTR-1614544 https://reactome.org/PathwayBrowser/#/R-XTR-1614544 Sulfite is oxidized to sulfate IEA Xenopus tropicalis 17359 R-XTR-1614605 https://reactome.org/PathwayBrowser/#/R-XTR-1614605 Persulfide sulfur is dioxygenated IEA Xenopus tropicalis 17359 R-XTR-1655879 https://reactome.org/PathwayBrowser/#/R-XTR-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Xenopus tropicalis 17359 R-XTR-9013198 https://reactome.org/PathwayBrowser/#/R-XTR-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Xenopus tropicalis 17361 R-HSA-9683769 https://reactome.org/PathwayBrowser/#/R-HSA-9683769 O-glycosylation of 3a is terminated TAS Homo sapiens 17361 R-HSA-9694718 https://reactome.org/PathwayBrowser/#/R-HSA-9694718 O-glycosylation of 3a is terminated IEA Homo sapiens 17362 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 17362 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 17362 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 17362 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 17362 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 17362 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 17362 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 17362 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 17362 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 17364 R-BTA-428015 https://reactome.org/PathwayBrowser/#/R-BTA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Bos taurus 17364 R-BTA-6810076 https://reactome.org/PathwayBrowser/#/R-BTA-6810076 DDO oxidizes D-Asp to OA IEA Bos taurus 17364 R-CEL-428015 https://reactome.org/PathwayBrowser/#/R-CEL-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 17364 R-CEL-6810076 https://reactome.org/PathwayBrowser/#/R-CEL-6810076 DDO oxidizes D-Asp to OA IEA Caenorhabditis elegans 17364 R-CFA-428015 https://reactome.org/PathwayBrowser/#/R-CFA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Canis familiaris 17364 R-CFA-6810076 https://reactome.org/PathwayBrowser/#/R-CFA-6810076 DDO oxidizes D-Asp to OA IEA Canis familiaris 17364 R-DDI-6810076 https://reactome.org/PathwayBrowser/#/R-DDI-6810076 DDO oxidizes D-Asp to OA IEA Dictyostelium discoideum 17364 R-DME-428015 https://reactome.org/PathwayBrowser/#/R-DME-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Drosophila melanogaster 17364 R-DME-6810076 https://reactome.org/PathwayBrowser/#/R-DME-6810076 DDO oxidizes D-Asp to OA IEA Drosophila melanogaster 17364 R-DRE-428015 https://reactome.org/PathwayBrowser/#/R-DRE-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Danio rerio 17364 R-GGA-428015 https://reactome.org/PathwayBrowser/#/R-GGA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Gallus gallus 17364 R-GGA-6810076 https://reactome.org/PathwayBrowser/#/R-GGA-6810076 DDO oxidizes D-Asp to OA IEA Gallus gallus 17364 R-HSA-428015 https://reactome.org/PathwayBrowser/#/R-HSA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 17364 R-HSA-5625015 https://reactome.org/PathwayBrowser/#/R-HSA-5625015 Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 17364 R-HSA-5625029 https://reactome.org/PathwayBrowser/#/R-HSA-5625029 SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 17364 R-HSA-6810076 https://reactome.org/PathwayBrowser/#/R-HSA-6810076 DDO oxidizes D-Asp to OA TAS Homo sapiens 17364 R-MMU-428015 https://reactome.org/PathwayBrowser/#/R-MMU-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Mus musculus 17364 R-MMU-6810076 https://reactome.org/PathwayBrowser/#/R-MMU-6810076 DDO oxidizes D-Asp to OA IEA Mus musculus 17364 R-RNO-428015 https://reactome.org/PathwayBrowser/#/R-RNO-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Rattus norvegicus 17364 R-RNO-6810076 https://reactome.org/PathwayBrowser/#/R-RNO-6810076 DDO oxidizes D-Asp to OA IEA Rattus norvegicus 17364 R-SPO-6810076 https://reactome.org/PathwayBrowser/#/R-SPO-6810076 DDO oxidizes D-Asp to OA IEA Schizosaccharomyces pombe 17364 R-SSC-428015 https://reactome.org/PathwayBrowser/#/R-SSC-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Sus scrofa 17364 R-SSC-6810076 https://reactome.org/PathwayBrowser/#/R-SSC-6810076 DDO oxidizes D-Asp to OA IEA Sus scrofa 17364 R-XTR-428015 https://reactome.org/PathwayBrowser/#/R-XTR-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Xenopus tropicalis 17368 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17368 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17368 R-BTA-110251 https://reactome.org/PathwayBrowser/#/R-BTA-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Bos taurus 17368 R-BTA-112033 https://reactome.org/PathwayBrowser/#/R-BTA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Bos taurus 17368 R-BTA-74215 https://reactome.org/PathwayBrowser/#/R-BTA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Bos taurus 17368 R-BTA-74242 https://reactome.org/PathwayBrowser/#/R-BTA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Bos taurus 17368 R-BTA-74247 https://reactome.org/PathwayBrowser/#/R-BTA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Bos taurus 17368 R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 17368 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17368 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17368 R-CEL-112033 https://reactome.org/PathwayBrowser/#/R-CEL-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Caenorhabditis elegans 17368 R-CEL-74215 https://reactome.org/PathwayBrowser/#/R-CEL-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Caenorhabditis elegans 17368 R-CEL-74242 https://reactome.org/PathwayBrowser/#/R-CEL-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Caenorhabditis elegans 17368 R-CEL-74247 https://reactome.org/PathwayBrowser/#/R-CEL-74247 XDH oxidizes hypoxanthine to form xanthine IEA Caenorhabditis elegans 17368 R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 17368 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17368 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17368 R-CFA-110251 https://reactome.org/PathwayBrowser/#/R-CFA-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Canis familiaris 17368 R-CFA-112033 https://reactome.org/PathwayBrowser/#/R-CFA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Canis familiaris 17368 R-CFA-74215 https://reactome.org/PathwayBrowser/#/R-CFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Canis familiaris 17368 R-CFA-74242 https://reactome.org/PathwayBrowser/#/R-CFA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Canis familiaris 17368 R-CFA-74247 https://reactome.org/PathwayBrowser/#/R-CFA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Canis familiaris 17368 R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 17368 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17368 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17368 R-DDI-74215 https://reactome.org/PathwayBrowser/#/R-DDI-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Dictyostelium discoideum 17368 R-DDI-74247 https://reactome.org/PathwayBrowser/#/R-DDI-74247 XDH oxidizes hypoxanthine to form xanthine IEA Dictyostelium discoideum 17368 R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 17368 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17368 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17368 R-DME-112033 https://reactome.org/PathwayBrowser/#/R-DME-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Drosophila melanogaster 17368 R-DME-74242 https://reactome.org/PathwayBrowser/#/R-DME-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Drosophila melanogaster 17368 R-DME-74247 https://reactome.org/PathwayBrowser/#/R-DME-74247 XDH oxidizes hypoxanthine to form xanthine IEA Drosophila melanogaster 17368 R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 17368 R-DRE-110251 https://reactome.org/PathwayBrowser/#/R-DRE-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Danio rerio 17368 R-DRE-112033 https://reactome.org/PathwayBrowser/#/R-DRE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Danio rerio 17368 R-DRE-74215 https://reactome.org/PathwayBrowser/#/R-DRE-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Danio rerio 17368 R-DRE-74242 https://reactome.org/PathwayBrowser/#/R-DRE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Danio rerio 17368 R-GGA-110251 https://reactome.org/PathwayBrowser/#/R-GGA-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Gallus gallus 17368 R-GGA-421161 https://reactome.org/PathwayBrowser/#/R-GGA-421161 hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ TAS Gallus gallus 17368 R-GGA-421174 https://reactome.org/PathwayBrowser/#/R-GGA-421174 inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate IEA Gallus gallus 17368 R-GGA-74215 https://reactome.org/PathwayBrowser/#/R-GGA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Gallus gallus 17368 R-GGA-74247 https://reactome.org/PathwayBrowser/#/R-GGA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Gallus gallus 17368 R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 17368 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17368 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17368 R-HSA-110251 https://reactome.org/PathwayBrowser/#/R-HSA-110251 Cleavage of hypoxanthine by MPG glycosylase TAS Homo sapiens 17368 R-HSA-112033 https://reactome.org/PathwayBrowser/#/R-HSA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine TAS Homo sapiens 17368 R-HSA-74215 https://reactome.org/PathwayBrowser/#/R-HSA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 17368 R-HSA-74242 https://reactome.org/PathwayBrowser/#/R-HSA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 17368 R-HSA-74247 https://reactome.org/PathwayBrowser/#/R-HSA-74247 XDH oxidizes hypoxanthine to form xanthine TAS Homo sapiens 17368 R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 17368 R-HSA-9734274 https://reactome.org/PathwayBrowser/#/R-HSA-9734274 Defective HPRT1 does not convert guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 17368 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17368 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17368 R-MMU-110251 https://reactome.org/PathwayBrowser/#/R-MMU-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Mus musculus 17368 R-MMU-112033 https://reactome.org/PathwayBrowser/#/R-MMU-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Mus musculus 17368 R-MMU-74215 https://reactome.org/PathwayBrowser/#/R-MMU-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Mus musculus 17368 R-MMU-74242 https://reactome.org/PathwayBrowser/#/R-MMU-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Mus musculus 17368 R-MMU-74247 https://reactome.org/PathwayBrowser/#/R-MMU-74247 XDH oxidizes hypoxanthine to form xanthine IEA Mus musculus 17368 R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 17368 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17368 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17368 R-PFA-110251 https://reactome.org/PathwayBrowser/#/R-PFA-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Plasmodium falciparum 17368 R-PFA-74215 https://reactome.org/PathwayBrowser/#/R-PFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Plasmodium falciparum 17368 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17368 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17368 R-RNO-110251 https://reactome.org/PathwayBrowser/#/R-RNO-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Rattus norvegicus 17368 R-RNO-112033 https://reactome.org/PathwayBrowser/#/R-RNO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Rattus norvegicus 17368 R-RNO-74215 https://reactome.org/PathwayBrowser/#/R-RNO-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Rattus norvegicus 17368 R-RNO-74242 https://reactome.org/PathwayBrowser/#/R-RNO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Rattus norvegicus 17368 R-RNO-74247 https://reactome.org/PathwayBrowser/#/R-RNO-74247 XDH oxidizes hypoxanthine to form xanthine IEA Rattus norvegicus 17368 R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 17368 R-SCE-112033 https://reactome.org/PathwayBrowser/#/R-SCE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Saccharomyces cerevisiae 17368 R-SCE-74242 https://reactome.org/PathwayBrowser/#/R-SCE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Saccharomyces cerevisiae 17368 R-SPO-112033 https://reactome.org/PathwayBrowser/#/R-SPO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Schizosaccharomyces pombe 17368 R-SPO-74242 https://reactome.org/PathwayBrowser/#/R-SPO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Schizosaccharomyces pombe 17368 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17368 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17368 R-SSC-110251 https://reactome.org/PathwayBrowser/#/R-SSC-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Sus scrofa 17368 R-SSC-112033 https://reactome.org/PathwayBrowser/#/R-SSC-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Sus scrofa 17368 R-SSC-74215 https://reactome.org/PathwayBrowser/#/R-SSC-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Sus scrofa 17368 R-SSC-74242 https://reactome.org/PathwayBrowser/#/R-SSC-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Sus scrofa 17368 R-SSC-74247 https://reactome.org/PathwayBrowser/#/R-SSC-74247 XDH oxidizes hypoxanthine to form xanthine IEA Sus scrofa 17368 R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 17368 R-XTR-110251 https://reactome.org/PathwayBrowser/#/R-XTR-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Xenopus tropicalis 17368 R-XTR-112033 https://reactome.org/PathwayBrowser/#/R-XTR-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Xenopus tropicalis 17368 R-XTR-74242 https://reactome.org/PathwayBrowser/#/R-XTR-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Xenopus tropicalis 17368 R-XTR-74247 https://reactome.org/PathwayBrowser/#/R-XTR-74247 XDH oxidizes hypoxanthine to form xanthine IEA Xenopus tropicalis 17368 R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 17369 R-BTA-446201 https://reactome.org/PathwayBrowser/#/R-BTA-446201 PMM1,2 isomerise Man6P to Man1P IEA Bos taurus 17369 R-BTA-532549 https://reactome.org/PathwayBrowser/#/R-BTA-532549 MPI isomerises Fru6P to Man6P IEA Bos taurus 17369 R-CEL-446201 https://reactome.org/PathwayBrowser/#/R-CEL-446201 PMM1,2 isomerise Man6P to Man1P IEA Caenorhabditis elegans 17369 R-CEL-532549 https://reactome.org/PathwayBrowser/#/R-CEL-532549 MPI isomerises Fru6P to Man6P IEA Caenorhabditis elegans 17369 R-CFA-446201 https://reactome.org/PathwayBrowser/#/R-CFA-446201 PMM1,2 isomerise Man6P to Man1P IEA Canis familiaris 17369 R-CFA-532549 https://reactome.org/PathwayBrowser/#/R-CFA-532549 MPI isomerises Fru6P to Man6P IEA Canis familiaris 17369 R-DDI-446201 https://reactome.org/PathwayBrowser/#/R-DDI-446201 PMM1,2 isomerise Man6P to Man1P IEA Dictyostelium discoideum 17369 R-DDI-532549 https://reactome.org/PathwayBrowser/#/R-DDI-532549 MPI isomerises Fru6P to Man6P IEA Dictyostelium discoideum 17369 R-DME-446201 https://reactome.org/PathwayBrowser/#/R-DME-446201 PMM1,2 isomerise Man6P to Man1P IEA Drosophila melanogaster 17369 R-DME-532549 https://reactome.org/PathwayBrowser/#/R-DME-532549 MPI isomerises Fru6P to Man6P IEA Drosophila melanogaster 17369 R-DRE-446201 https://reactome.org/PathwayBrowser/#/R-DRE-446201 PMM1,2 isomerise Man6P to Man1P IEA Danio rerio 17369 R-DRE-532549 https://reactome.org/PathwayBrowser/#/R-DRE-532549 MPI isomerises Fru6P to Man6P IEA Danio rerio 17369 R-GGA-446201 https://reactome.org/PathwayBrowser/#/R-GGA-446201 PMM1,2 isomerise Man6P to Man1P IEA Gallus gallus 17369 R-GGA-532549 https://reactome.org/PathwayBrowser/#/R-GGA-532549 MPI isomerises Fru6P to Man6P IEA Gallus gallus 17369 R-HSA-3781926 https://reactome.org/PathwayBrowser/#/R-HSA-3781926 Defective PMM2 does not isomerise Man6P to Man1P TAS Homo sapiens 17369 R-HSA-446201 https://reactome.org/PathwayBrowser/#/R-HSA-446201 PMM1,2 isomerise Man6P to Man1P TAS Homo sapiens 17369 R-HSA-532549 https://reactome.org/PathwayBrowser/#/R-HSA-532549 MPI isomerises Fru6P to Man6P TAS Homo sapiens 17369 R-MMU-446201 https://reactome.org/PathwayBrowser/#/R-MMU-446201 PMM1,2 isomerise Man6P to Man1P IEA Mus musculus 17369 R-MMU-532549 https://reactome.org/PathwayBrowser/#/R-MMU-532549 MPI isomerises Fru6P to Man6P IEA Mus musculus 17369 R-PFA-446201 https://reactome.org/PathwayBrowser/#/R-PFA-446201 PMM1,2 isomerise Man6P to Man1P IEA Plasmodium falciparum 17369 R-PFA-532549 https://reactome.org/PathwayBrowser/#/R-PFA-532549 MPI isomerises Fru6P to Man6P IEA Plasmodium falciparum 17369 R-RNO-446201 https://reactome.org/PathwayBrowser/#/R-RNO-446201 PMM1,2 isomerise Man6P to Man1P IEA Rattus norvegicus 17369 R-RNO-532549 https://reactome.org/PathwayBrowser/#/R-RNO-532549 MPI isomerises Fru6P to Man6P IEA Rattus norvegicus 17369 R-SCE-446201 https://reactome.org/PathwayBrowser/#/R-SCE-446201 PMM1,2 isomerise Man6P to Man1P IEA Saccharomyces cerevisiae 17369 R-SCE-532549 https://reactome.org/PathwayBrowser/#/R-SCE-532549 MPI isomerises Fru6P to Man6P IEA Saccharomyces cerevisiae 17369 R-SPO-446201 https://reactome.org/PathwayBrowser/#/R-SPO-446201 PMM1,2 isomerise Man6P to Man1P IEA Schizosaccharomyces pombe 17369 R-SPO-532549 https://reactome.org/PathwayBrowser/#/R-SPO-532549 MPI isomerises Fru6P to Man6P IEA Schizosaccharomyces pombe 17369 R-SSC-446201 https://reactome.org/PathwayBrowser/#/R-SSC-446201 PMM1,2 isomerise Man6P to Man1P IEA Sus scrofa 17369 R-SSC-532549 https://reactome.org/PathwayBrowser/#/R-SSC-532549 MPI isomerises Fru6P to Man6P IEA Sus scrofa 17369 R-XTR-446201 https://reactome.org/PathwayBrowser/#/R-XTR-446201 PMM1,2 isomerise Man6P to Man1P IEA Xenopus tropicalis 17369 R-XTR-532549 https://reactome.org/PathwayBrowser/#/R-XTR-532549 MPI isomerises Fru6P to Man6P IEA Xenopus tropicalis 17378 R-BTA-6813749 https://reactome.org/PathwayBrowser/#/R-BTA-6813749 ALDH1A1 oxidises GA to DGA IEA Bos taurus 17378 R-BTA-70342 https://reactome.org/PathwayBrowser/#/R-BTA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Bos taurus 17378 R-BTA-70349 https://reactome.org/PathwayBrowser/#/R-BTA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Bos taurus 17378 R-CEL-6813749 https://reactome.org/PathwayBrowser/#/R-CEL-6813749 ALDH1A1 oxidises GA to DGA IEA Caenorhabditis elegans 17378 R-CEL-70342 https://reactome.org/PathwayBrowser/#/R-CEL-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Caenorhabditis elegans 17378 R-CEL-70349 https://reactome.org/PathwayBrowser/#/R-CEL-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 17378 R-CFA-6813749 https://reactome.org/PathwayBrowser/#/R-CFA-6813749 ALDH1A1 oxidises GA to DGA IEA Canis familiaris 17378 R-CFA-70342 https://reactome.org/PathwayBrowser/#/R-CFA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Canis familiaris 17378 R-CFA-70349 https://reactome.org/PathwayBrowser/#/R-CFA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Canis familiaris 17378 R-DDI-6813749 https://reactome.org/PathwayBrowser/#/R-DDI-6813749 ALDH1A1 oxidises GA to DGA IEA Dictyostelium discoideum 17378 R-DDI-70342 https://reactome.org/PathwayBrowser/#/R-DDI-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Dictyostelium discoideum 17378 R-DDI-70349 https://reactome.org/PathwayBrowser/#/R-DDI-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 17378 R-DME-6813749 https://reactome.org/PathwayBrowser/#/R-DME-6813749 ALDH1A1 oxidises GA to DGA IEA Drosophila melanogaster 17378 R-DME-70342 https://reactome.org/PathwayBrowser/#/R-DME-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Drosophila melanogaster 17378 R-DRE-70342 https://reactome.org/PathwayBrowser/#/R-DRE-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Danio rerio 17378 R-DRE-70349 https://reactome.org/PathwayBrowser/#/R-DRE-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Danio rerio 17378 R-GGA-6813749 https://reactome.org/PathwayBrowser/#/R-GGA-6813749 ALDH1A1 oxidises GA to DGA IEA Gallus gallus 17378 R-GGA-70342 https://reactome.org/PathwayBrowser/#/R-GGA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Gallus gallus 17378 R-GGA-70349 https://reactome.org/PathwayBrowser/#/R-GGA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Gallus gallus 17378 R-HSA-6813749 https://reactome.org/PathwayBrowser/#/R-HSA-6813749 ALDH1A1 oxidises GA to DGA TAS Homo sapiens 17378 R-HSA-70342 https://reactome.org/PathwayBrowser/#/R-HSA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP TAS Homo sapiens 17378 R-HSA-70349 https://reactome.org/PathwayBrowser/#/R-HSA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate TAS Homo sapiens 17378 R-MMU-6813749 https://reactome.org/PathwayBrowser/#/R-MMU-6813749 ALDH1A1 oxidises GA to DGA IEA Mus musculus 17378 R-MMU-70342 https://reactome.org/PathwayBrowser/#/R-MMU-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Mus musculus 17378 R-MMU-70349 https://reactome.org/PathwayBrowser/#/R-MMU-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Mus musculus 17378 R-PFA-70342 https://reactome.org/PathwayBrowser/#/R-PFA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Plasmodium falciparum 17378 R-RNO-6813749 https://reactome.org/PathwayBrowser/#/R-RNO-6813749 ALDH1A1 oxidises GA to DGA IEA Rattus norvegicus 17378 R-RNO-70342 https://reactome.org/PathwayBrowser/#/R-RNO-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Rattus norvegicus 17378 R-RNO-70349 https://reactome.org/PathwayBrowser/#/R-RNO-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 17378 R-SCE-6813749 https://reactome.org/PathwayBrowser/#/R-SCE-6813749 ALDH1A1 oxidises GA to DGA IEA Saccharomyces cerevisiae 17378 R-SCE-70349 https://reactome.org/PathwayBrowser/#/R-SCE-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Saccharomyces cerevisiae 17378 R-SPO-6813749 https://reactome.org/PathwayBrowser/#/R-SPO-6813749 ALDH1A1 oxidises GA to DGA IEA Schizosaccharomyces pombe 17378 R-SPO-70349 https://reactome.org/PathwayBrowser/#/R-SPO-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Schizosaccharomyces pombe 17378 R-SSC-6813749 https://reactome.org/PathwayBrowser/#/R-SSC-6813749 ALDH1A1 oxidises GA to DGA IEA Sus scrofa 17378 R-SSC-70342 https://reactome.org/PathwayBrowser/#/R-SSC-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Sus scrofa 17378 R-SSC-70349 https://reactome.org/PathwayBrowser/#/R-SSC-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Sus scrofa 17378 R-XTR-6813749 https://reactome.org/PathwayBrowser/#/R-XTR-6813749 ALDH1A1 oxidises GA to DGA IEA Xenopus tropicalis 17378 R-XTR-70342 https://reactome.org/PathwayBrowser/#/R-XTR-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Xenopus tropicalis 17380 R-BTA-71200 https://reactome.org/PathwayBrowser/#/R-BTA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Bos taurus 17380 R-BTA-71217 https://reactome.org/PathwayBrowser/#/R-BTA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Bos taurus 17380 R-CEL-71200 https://reactome.org/PathwayBrowser/#/R-CEL-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Caenorhabditis elegans 17380 R-CEL-71217 https://reactome.org/PathwayBrowser/#/R-CEL-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Caenorhabditis elegans 17380 R-CFA-71200 https://reactome.org/PathwayBrowser/#/R-CFA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Canis familiaris 17380 R-CFA-71217 https://reactome.org/PathwayBrowser/#/R-CFA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Canis familiaris 17380 R-DDI-71200 https://reactome.org/PathwayBrowser/#/R-DDI-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Dictyostelium discoideum 17380 R-DDI-71217 https://reactome.org/PathwayBrowser/#/R-DDI-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Dictyostelium discoideum 17380 R-DME-71200 https://reactome.org/PathwayBrowser/#/R-DME-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Drosophila melanogaster 17380 R-DRE-71200 https://reactome.org/PathwayBrowser/#/R-DRE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Danio rerio 17380 R-GGA-71200 https://reactome.org/PathwayBrowser/#/R-GGA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Gallus gallus 17380 R-GGA-71217 https://reactome.org/PathwayBrowser/#/R-GGA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Gallus gallus 17380 R-HSA-71200 https://reactome.org/PathwayBrowser/#/R-HSA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O TAS Homo sapiens 17380 R-HSA-71217 https://reactome.org/PathwayBrowser/#/R-HSA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine TAS Homo sapiens 17380 R-MMU-71200 https://reactome.org/PathwayBrowser/#/R-MMU-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Mus musculus 17380 R-MMU-71217 https://reactome.org/PathwayBrowser/#/R-MMU-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Mus musculus 17380 R-RNO-71200 https://reactome.org/PathwayBrowser/#/R-RNO-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Rattus norvegicus 17380 R-RNO-71217 https://reactome.org/PathwayBrowser/#/R-RNO-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Rattus norvegicus 17380 R-SCE-71200 https://reactome.org/PathwayBrowser/#/R-SCE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Saccharomyces cerevisiae 17380 R-SCE-71217 https://reactome.org/PathwayBrowser/#/R-SCE-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Saccharomyces cerevisiae 17380 R-SSC-71200 https://reactome.org/PathwayBrowser/#/R-SSC-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Sus scrofa 17380 R-SSC-71217 https://reactome.org/PathwayBrowser/#/R-SSC-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Sus scrofa 17380 R-XTR-71200 https://reactome.org/PathwayBrowser/#/R-XTR-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Xenopus tropicalis 17380 R-XTR-71217 https://reactome.org/PathwayBrowser/#/R-XTR-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Xenopus tropicalis 17388 R-BTA-6783939 https://reactome.org/PathwayBrowser/#/R-BTA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 17388 R-BTA-6783955 https://reactome.org/PathwayBrowser/#/R-BTA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 17388 R-BTA-70664 https://reactome.org/PathwayBrowser/#/R-BTA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 17388 R-BTA-70670 https://reactome.org/PathwayBrowser/#/R-BTA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Bos taurus 17388 R-BTA-8955817 https://reactome.org/PathwayBrowser/#/R-BTA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Bos taurus 17388 R-CEL-6783939 https://reactome.org/PathwayBrowser/#/R-CEL-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 17388 R-CEL-70664 https://reactome.org/PathwayBrowser/#/R-CEL-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 17388 R-CEL-70670 https://reactome.org/PathwayBrowser/#/R-CEL-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Caenorhabditis elegans 17388 R-CEL-8955817 https://reactome.org/PathwayBrowser/#/R-CEL-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Caenorhabditis elegans 17388 R-CFA-6783939 https://reactome.org/PathwayBrowser/#/R-CFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 17388 R-CFA-6783955 https://reactome.org/PathwayBrowser/#/R-CFA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 17388 R-CFA-70664 https://reactome.org/PathwayBrowser/#/R-CFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 17388 R-CFA-70670 https://reactome.org/PathwayBrowser/#/R-CFA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Canis familiaris 17388 R-CFA-8955817 https://reactome.org/PathwayBrowser/#/R-CFA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Canis familiaris 17388 R-DDI-6783939 https://reactome.org/PathwayBrowser/#/R-DDI-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 17388 R-DDI-6783955 https://reactome.org/PathwayBrowser/#/R-DDI-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 17388 R-DDI-70664 https://reactome.org/PathwayBrowser/#/R-DDI-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 17388 R-DDI-70670 https://reactome.org/PathwayBrowser/#/R-DDI-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Dictyostelium discoideum 17388 R-DDI-8955817 https://reactome.org/PathwayBrowser/#/R-DDI-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Dictyostelium discoideum 17388 R-DME-6783939 https://reactome.org/PathwayBrowser/#/R-DME-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 17388 R-DME-70664 https://reactome.org/PathwayBrowser/#/R-DME-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 17388 R-DME-70670 https://reactome.org/PathwayBrowser/#/R-DME-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Drosophila melanogaster 17388 R-DME-8955817 https://reactome.org/PathwayBrowser/#/R-DME-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Drosophila melanogaster 17388 R-DRE-6783939 https://reactome.org/PathwayBrowser/#/R-DRE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 17388 R-DRE-6783955 https://reactome.org/PathwayBrowser/#/R-DRE-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 17388 R-DRE-70664 https://reactome.org/PathwayBrowser/#/R-DRE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 17388 R-GGA-6783939 https://reactome.org/PathwayBrowser/#/R-GGA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 17388 R-GGA-6783955 https://reactome.org/PathwayBrowser/#/R-GGA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 17388 R-GGA-70664 https://reactome.org/PathwayBrowser/#/R-GGA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 17388 R-GGA-70670 https://reactome.org/PathwayBrowser/#/R-GGA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Gallus gallus 17388 R-HSA-6783939 https://reactome.org/PathwayBrowser/#/R-HSA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 17388 R-HSA-6783955 https://reactome.org/PathwayBrowser/#/R-HSA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 17388 R-HSA-70655 https://reactome.org/PathwayBrowser/#/R-HSA-70655 L-glutamate gamma-semialdehyde <=> L-1-pyrroline-5-carboxylate TAS Homo sapiens 17388 R-HSA-70664 https://reactome.org/PathwayBrowser/#/R-HSA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 17388 R-HSA-70667 https://reactome.org/PathwayBrowser/#/R-HSA-70667 1PYR-5COOH spontaneously hydrolyses to L-GluSS TAS Homo sapiens 17388 R-HSA-70670 https://reactome.org/PathwayBrowser/#/R-HSA-70670 PRODH oxidises L-Pro to 1PYR-5COOH TAS Homo sapiens 17388 R-HSA-8955817 https://reactome.org/PathwayBrowser/#/R-HSA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH TAS Homo sapiens 17388 R-MMU-6783939 https://reactome.org/PathwayBrowser/#/R-MMU-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 17388 R-MMU-6783955 https://reactome.org/PathwayBrowser/#/R-MMU-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 17388 R-MMU-70664 https://reactome.org/PathwayBrowser/#/R-MMU-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 17388 R-MMU-70670 https://reactome.org/PathwayBrowser/#/R-MMU-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Mus musculus 17388 R-MMU-8955817 https://reactome.org/PathwayBrowser/#/R-MMU-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Mus musculus 17388 R-PFA-6783939 https://reactome.org/PathwayBrowser/#/R-PFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 17388 R-PFA-6783955 https://reactome.org/PathwayBrowser/#/R-PFA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 17388 R-PFA-70664 https://reactome.org/PathwayBrowser/#/R-PFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 17388 R-RNO-6783939 https://reactome.org/PathwayBrowser/#/R-RNO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 17388 R-RNO-6783955 https://reactome.org/PathwayBrowser/#/R-RNO-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 17388 R-RNO-70664 https://reactome.org/PathwayBrowser/#/R-RNO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 17388 R-RNO-70670 https://reactome.org/PathwayBrowser/#/R-RNO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Rattus norvegicus 17388 R-RNO-8955817 https://reactome.org/PathwayBrowser/#/R-RNO-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Rattus norvegicus 17388 R-SCE-6783939 https://reactome.org/PathwayBrowser/#/R-SCE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 17388 R-SCE-6783955 https://reactome.org/PathwayBrowser/#/R-SCE-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 17388 R-SCE-70664 https://reactome.org/PathwayBrowser/#/R-SCE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 17388 R-SCE-70670 https://reactome.org/PathwayBrowser/#/R-SCE-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Saccharomyces cerevisiae 17388 R-SCE-8955817 https://reactome.org/PathwayBrowser/#/R-SCE-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Saccharomyces cerevisiae 17388 R-SPO-6783939 https://reactome.org/PathwayBrowser/#/R-SPO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 17388 R-SPO-6783955 https://reactome.org/PathwayBrowser/#/R-SPO-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 17388 R-SPO-70664 https://reactome.org/PathwayBrowser/#/R-SPO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 17388 R-SPO-70670 https://reactome.org/PathwayBrowser/#/R-SPO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Schizosaccharomyces pombe 17388 R-SPO-8955817 https://reactome.org/PathwayBrowser/#/R-SPO-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Schizosaccharomyces pombe 17388 R-SSC-6783939 https://reactome.org/PathwayBrowser/#/R-SSC-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 17388 R-SSC-6783955 https://reactome.org/PathwayBrowser/#/R-SSC-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 17388 R-SSC-70664 https://reactome.org/PathwayBrowser/#/R-SSC-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 17388 R-SSC-70670 https://reactome.org/PathwayBrowser/#/R-SSC-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Sus scrofa 17388 R-SSC-8955817 https://reactome.org/PathwayBrowser/#/R-SSC-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Sus scrofa 17388 R-XTR-6783939 https://reactome.org/PathwayBrowser/#/R-XTR-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 17388 R-XTR-70664 https://reactome.org/PathwayBrowser/#/R-XTR-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 17388 R-XTR-70670 https://reactome.org/PathwayBrowser/#/R-XTR-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Xenopus tropicalis 17388 R-XTR-8955817 https://reactome.org/PathwayBrowser/#/R-XTR-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Xenopus tropicalis 17389 R-BTA-1482543 https://reactome.org/PathwayBrowser/#/R-BTA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Bos taurus 17389 R-BTA-1482647 https://reactome.org/PathwayBrowser/#/R-BTA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Bos taurus 17389 R-BTA-1482654 https://reactome.org/PathwayBrowser/#/R-BTA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Bos taurus 17389 R-BTA-1482811 https://reactome.org/PathwayBrowser/#/R-BTA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Bos taurus 17389 R-BTA-6800334 https://reactome.org/PathwayBrowser/#/R-BTA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Bos taurus 17389 R-CEL-1482647 https://reactome.org/PathwayBrowser/#/R-CEL-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Caenorhabditis elegans 17389 R-CEL-1482654 https://reactome.org/PathwayBrowser/#/R-CEL-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Caenorhabditis elegans 17389 R-CEL-1482811 https://reactome.org/PathwayBrowser/#/R-CEL-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Caenorhabditis elegans 17389 R-CEL-6800334 https://reactome.org/PathwayBrowser/#/R-CEL-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Caenorhabditis elegans 17389 R-CFA-1482543 https://reactome.org/PathwayBrowser/#/R-CFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Canis familiaris 17389 R-CFA-1482647 https://reactome.org/PathwayBrowser/#/R-CFA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Canis familiaris 17389 R-CFA-1482654 https://reactome.org/PathwayBrowser/#/R-CFA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Canis familiaris 17389 R-CFA-1482811 https://reactome.org/PathwayBrowser/#/R-CFA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Canis familiaris 17389 R-CFA-6800334 https://reactome.org/PathwayBrowser/#/R-CFA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Canis familiaris 17389 R-DDI-1482543 https://reactome.org/PathwayBrowser/#/R-DDI-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Dictyostelium discoideum 17389 R-DDI-6800334 https://reactome.org/PathwayBrowser/#/R-DDI-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Dictyostelium discoideum 17389 R-DME-1482647 https://reactome.org/PathwayBrowser/#/R-DME-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Drosophila melanogaster 17389 R-DME-1482654 https://reactome.org/PathwayBrowser/#/R-DME-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Drosophila melanogaster 17389 R-DME-1482811 https://reactome.org/PathwayBrowser/#/R-DME-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Drosophila melanogaster 17389 R-DME-6800334 https://reactome.org/PathwayBrowser/#/R-DME-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Drosophila melanogaster 17389 R-DRE-1482543 https://reactome.org/PathwayBrowser/#/R-DRE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Danio rerio 17389 R-DRE-1482647 https://reactome.org/PathwayBrowser/#/R-DRE-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Danio rerio 17389 R-DRE-1482654 https://reactome.org/PathwayBrowser/#/R-DRE-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Danio rerio 17389 R-DRE-1482811 https://reactome.org/PathwayBrowser/#/R-DRE-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Danio rerio 17389 R-DRE-6800334 https://reactome.org/PathwayBrowser/#/R-DRE-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Danio rerio 17389 R-GGA-1482543 https://reactome.org/PathwayBrowser/#/R-GGA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Gallus gallus 17389 R-GGA-1482647 https://reactome.org/PathwayBrowser/#/R-GGA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Gallus gallus 17389 R-GGA-1482654 https://reactome.org/PathwayBrowser/#/R-GGA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Gallus gallus 17389 R-GGA-1482811 https://reactome.org/PathwayBrowser/#/R-GGA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Gallus gallus 17389 R-GGA-6800334 https://reactome.org/PathwayBrowser/#/R-GGA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Gallus gallus 17389 R-HSA-1482543 https://reactome.org/PathwayBrowser/#/R-HSA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL TAS Homo sapiens 17389 R-HSA-1482647 https://reactome.org/PathwayBrowser/#/R-HSA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 TAS Homo sapiens 17389 R-HSA-1482654 https://reactome.org/PathwayBrowser/#/R-HSA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 TAS Homo sapiens 17389 R-HSA-1482811 https://reactome.org/PathwayBrowser/#/R-HSA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 TAS Homo sapiens 17389 R-HSA-163402 https://reactome.org/PathwayBrowser/#/R-HSA-163402 diacylglycerol + H2O -> 2-acylglycerol + fatty acid IEA Homo sapiens 17389 R-HSA-163595 https://reactome.org/PathwayBrowser/#/R-HSA-163595 2-acylglycerol + H2O -> glycerol + fatty acid IEA Homo sapiens 17389 R-HSA-6800334 https://reactome.org/PathwayBrowser/#/R-HSA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG TAS Homo sapiens 17389 R-MMU-1482543 https://reactome.org/PathwayBrowser/#/R-MMU-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Mus musculus 17389 R-MMU-1482647 https://reactome.org/PathwayBrowser/#/R-MMU-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Mus musculus 17389 R-MMU-1482654 https://reactome.org/PathwayBrowser/#/R-MMU-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Mus musculus 17389 R-MMU-1482811 https://reactome.org/PathwayBrowser/#/R-MMU-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Mus musculus 17389 R-MMU-6800334 https://reactome.org/PathwayBrowser/#/R-MMU-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Mus musculus 17389 R-PFA-1482543 https://reactome.org/PathwayBrowser/#/R-PFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Plasmodium falciparum 17389 R-PFA-1482647 https://reactome.org/PathwayBrowser/#/R-PFA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Plasmodium falciparum 17389 R-PFA-1482654 https://reactome.org/PathwayBrowser/#/R-PFA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Plasmodium falciparum 17389 R-PFA-1482811 https://reactome.org/PathwayBrowser/#/R-PFA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Plasmodium falciparum 17389 R-RNO-1482543 https://reactome.org/PathwayBrowser/#/R-RNO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Rattus norvegicus 17389 R-RNO-1482647 https://reactome.org/PathwayBrowser/#/R-RNO-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Rattus norvegicus 17389 R-RNO-1482654 https://reactome.org/PathwayBrowser/#/R-RNO-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Rattus norvegicus 17389 R-RNO-1482811 https://reactome.org/PathwayBrowser/#/R-RNO-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Rattus norvegicus 17389 R-RNO-163439 https://reactome.org/PathwayBrowser/#/R-RNO-163439 2-acylglycerol + H2O -> glycerol + fatty acid TAS Rattus norvegicus 17389 R-RNO-163440 https://reactome.org/PathwayBrowser/#/R-RNO-163440 diacylglycerol + H2O -> 2-acylglycerol + fatty acid TAS Rattus norvegicus 17389 R-RNO-6800334 https://reactome.org/PathwayBrowser/#/R-RNO-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Rattus norvegicus 17389 R-SCE-1482543 https://reactome.org/PathwayBrowser/#/R-SCE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Saccharomyces cerevisiae 17389 R-SCE-6800334 https://reactome.org/PathwayBrowser/#/R-SCE-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Saccharomyces cerevisiae 17389 R-SPO-1482543 https://reactome.org/PathwayBrowser/#/R-SPO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Schizosaccharomyces pombe 17389 R-SPO-6800334 https://reactome.org/PathwayBrowser/#/R-SPO-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Schizosaccharomyces pombe 17389 R-SSC-1482543 https://reactome.org/PathwayBrowser/#/R-SSC-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Sus scrofa 17389 R-SSC-1482647 https://reactome.org/PathwayBrowser/#/R-SSC-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Sus scrofa 17389 R-SSC-1482654 https://reactome.org/PathwayBrowser/#/R-SSC-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Sus scrofa 17389 R-SSC-1482811 https://reactome.org/PathwayBrowser/#/R-SSC-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Sus scrofa 17389 R-SSC-6800334 https://reactome.org/PathwayBrowser/#/R-SSC-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Sus scrofa 17389 R-XTR-1482543 https://reactome.org/PathwayBrowser/#/R-XTR-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Xenopus tropicalis 17389 R-XTR-1482647 https://reactome.org/PathwayBrowser/#/R-XTR-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Xenopus tropicalis 17389 R-XTR-1482654 https://reactome.org/PathwayBrowser/#/R-XTR-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Xenopus tropicalis 17389 R-XTR-1482811 https://reactome.org/PathwayBrowser/#/R-XTR-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Xenopus tropicalis 17389 R-XTR-6800334 https://reactome.org/PathwayBrowser/#/R-XTR-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Xenopus tropicalis 17399 R-BTA-5661240 https://reactome.org/PathwayBrowser/#/R-BTA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Bos taurus 17399 R-CEL-5661240 https://reactome.org/PathwayBrowser/#/R-CEL-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Caenorhabditis elegans 17399 R-CFA-5661240 https://reactome.org/PathwayBrowser/#/R-CFA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Canis familiaris 17399 R-DME-5661240 https://reactome.org/PathwayBrowser/#/R-DME-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Drosophila melanogaster 17399 R-DRE-5661240 https://reactome.org/PathwayBrowser/#/R-DRE-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Danio rerio 17399 R-GGA-5661240 https://reactome.org/PathwayBrowser/#/R-GGA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Gallus gallus 17399 R-HSA-5661240 https://reactome.org/PathwayBrowser/#/R-HSA-5661240 DCXR tetramer reduces L-xylulose to xylitol TAS Homo sapiens 17399 R-HSA-5662473 https://reactome.org/PathwayBrowser/#/R-HSA-5662473 KGPDC decarboxylates 3-dehydro-L-gulonate to L-xylulose TAS Homo sapiens 17399 R-HSA-5662851 https://reactome.org/PathwayBrowser/#/R-HSA-5662851 Defective DCXR does not reduce L-xylulose to xylitol TAS Homo sapiens 17399 R-MMU-5661240 https://reactome.org/PathwayBrowser/#/R-MMU-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Mus musculus 17399 R-RNO-5661240 https://reactome.org/PathwayBrowser/#/R-RNO-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Rattus norvegicus 17399 R-SSC-5661240 https://reactome.org/PathwayBrowser/#/R-SSC-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Sus scrofa 17399 R-XTR-5661240 https://reactome.org/PathwayBrowser/#/R-XTR-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Xenopus tropicalis 17405 R-BTA-3204311 https://reactome.org/PathwayBrowser/#/R-BTA-3204311 AOX1 oxidises PXL to PDXate IEA Bos taurus 17405 R-CEL-3204311 https://reactome.org/PathwayBrowser/#/R-CEL-3204311 AOX1 oxidises PXL to PDXate IEA Caenorhabditis elegans 17405 R-DDI-3204311 https://reactome.org/PathwayBrowser/#/R-DDI-3204311 AOX1 oxidises PXL to PDXate IEA Dictyostelium discoideum 17405 R-DME-3204311 https://reactome.org/PathwayBrowser/#/R-DME-3204311 AOX1 oxidises PXL to PDXate IEA Drosophila melanogaster 17405 R-DRE-3204311 https://reactome.org/PathwayBrowser/#/R-DRE-3204311 AOX1 oxidises PXL to PDXate IEA Danio rerio 17405 R-GGA-3204311 https://reactome.org/PathwayBrowser/#/R-GGA-3204311 AOX1 oxidises PXL to PDXate IEA Gallus gallus 17405 R-HSA-3204311 https://reactome.org/PathwayBrowser/#/R-HSA-3204311 AOX1 oxidises PXL to PDXate TAS Homo sapiens 17405 R-MMU-3204311 https://reactome.org/PathwayBrowser/#/R-MMU-3204311 AOX1 oxidises PXL to PDXate IEA Mus musculus 17405 R-RNO-3204311 https://reactome.org/PathwayBrowser/#/R-RNO-3204311 AOX1 oxidises PXL to PDXate IEA Rattus norvegicus 17405 R-SSC-3204311 https://reactome.org/PathwayBrowser/#/R-SSC-3204311 AOX1 oxidises PXL to PDXate IEA Sus scrofa 17405 R-XTR-3204311 https://reactome.org/PathwayBrowser/#/R-XTR-3204311 AOX1 oxidises PXL to PDXate IEA Xenopus tropicalis 17408 R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 17408 R-BTA-192434 https://reactome.org/PathwayBrowser/#/R-BTA-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Bos taurus 17408 R-BTA-5696074 https://reactome.org/PathwayBrowser/#/R-BTA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Bos taurus 17408 R-BTA-5696448 https://reactome.org/PathwayBrowser/#/R-BTA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Bos taurus 17408 R-BTA-6814797 https://reactome.org/PathwayBrowser/#/R-BTA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Bos taurus 17408 R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 17408 R-CEL-5696074 https://reactome.org/PathwayBrowser/#/R-CEL-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Caenorhabditis elegans 17408 R-CEL-5696448 https://reactome.org/PathwayBrowser/#/R-CEL-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Caenorhabditis elegans 17408 R-CEL-6814797 https://reactome.org/PathwayBrowser/#/R-CEL-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Caenorhabditis elegans 17408 R-CFA-5696074 https://reactome.org/PathwayBrowser/#/R-CFA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Canis familiaris 17408 R-CFA-5696448 https://reactome.org/PathwayBrowser/#/R-CFA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Canis familiaris 17408 R-CFA-6814797 https://reactome.org/PathwayBrowser/#/R-CFA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Canis familiaris 17408 R-DDI-5696074 https://reactome.org/PathwayBrowser/#/R-DDI-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Dictyostelium discoideum 17408 R-DDI-5696448 https://reactome.org/PathwayBrowser/#/R-DDI-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Dictyostelium discoideum 17408 R-DDI-6814797 https://reactome.org/PathwayBrowser/#/R-DDI-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Dictyostelium discoideum 17408 R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 17408 R-DME-5696074 https://reactome.org/PathwayBrowser/#/R-DME-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Drosophila melanogaster 17408 R-DME-5696448 https://reactome.org/PathwayBrowser/#/R-DME-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Drosophila melanogaster 17408 R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 17408 R-DRE-5696074 https://reactome.org/PathwayBrowser/#/R-DRE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Danio rerio 17408 R-DRE-5696448 https://reactome.org/PathwayBrowser/#/R-DRE-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Danio rerio 17408 R-DRE-6814797 https://reactome.org/PathwayBrowser/#/R-DRE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Danio rerio 17408 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 17408 R-GGA-192434 https://reactome.org/PathwayBrowser/#/R-GGA-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Gallus gallus 17408 R-GGA-5696074 https://reactome.org/PathwayBrowser/#/R-GGA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Gallus gallus 17408 R-GGA-5696448 https://reactome.org/PathwayBrowser/#/R-GGA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Gallus gallus 17408 R-GGA-6814797 https://reactome.org/PathwayBrowser/#/R-GGA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Gallus gallus 17408 R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 17408 R-HSA-192434 https://reactome.org/PathwayBrowser/#/R-HSA-192434 Digestion of diacylglycerols by extracellular PTL:colipase TAS Homo sapiens 17408 R-HSA-5696074 https://reactome.org/PathwayBrowser/#/R-HSA-5696074 AGK:Mg2+ phosphorylates MAG, DAG TAS Homo sapiens 17408 R-HSA-5696448 https://reactome.org/PathwayBrowser/#/R-HSA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG TAS Homo sapiens 17408 R-HSA-6814797 https://reactome.org/PathwayBrowser/#/R-HSA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine TAS Homo sapiens 17408 R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 17408 R-MMU-192434 https://reactome.org/PathwayBrowser/#/R-MMU-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Mus musculus 17408 R-MMU-5696074 https://reactome.org/PathwayBrowser/#/R-MMU-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Mus musculus 17408 R-MMU-5696448 https://reactome.org/PathwayBrowser/#/R-MMU-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Mus musculus 17408 R-MMU-6814797 https://reactome.org/PathwayBrowser/#/R-MMU-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Mus musculus 17408 R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 17408 R-RNO-192434 https://reactome.org/PathwayBrowser/#/R-RNO-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Rattus norvegicus 17408 R-RNO-5696074 https://reactome.org/PathwayBrowser/#/R-RNO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Rattus norvegicus 17408 R-RNO-5696448 https://reactome.org/PathwayBrowser/#/R-RNO-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Rattus norvegicus 17408 R-RNO-6814797 https://reactome.org/PathwayBrowser/#/R-RNO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Rattus norvegicus 17408 R-SCE-5696074 https://reactome.org/PathwayBrowser/#/R-SCE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Saccharomyces cerevisiae 17408 R-SCE-5696448 https://reactome.org/PathwayBrowser/#/R-SCE-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Saccharomyces cerevisiae 17408 R-SCE-6814797 https://reactome.org/PathwayBrowser/#/R-SCE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Saccharomyces cerevisiae 17408 R-SPO-5696074 https://reactome.org/PathwayBrowser/#/R-SPO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Schizosaccharomyces pombe 17408 R-SPO-5696448 https://reactome.org/PathwayBrowser/#/R-SPO-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Schizosaccharomyces pombe 17408 R-SPO-6814797 https://reactome.org/PathwayBrowser/#/R-SPO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Schizosaccharomyces pombe 17408 R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 17408 R-SSC-192434 https://reactome.org/PathwayBrowser/#/R-SSC-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Sus scrofa 17408 R-SSC-5696074 https://reactome.org/PathwayBrowser/#/R-SSC-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Sus scrofa 17408 R-SSC-5696448 https://reactome.org/PathwayBrowser/#/R-SSC-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Sus scrofa 17408 R-SSC-6814797 https://reactome.org/PathwayBrowser/#/R-SSC-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Sus scrofa 17408 R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 17408 R-XTR-192434 https://reactome.org/PathwayBrowser/#/R-XTR-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis 17408 R-XTR-5696074 https://reactome.org/PathwayBrowser/#/R-XTR-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Xenopus tropicalis 17408 R-XTR-5696448 https://reactome.org/PathwayBrowser/#/R-XTR-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Xenopus tropicalis 17408 R-XTR-6814797 https://reactome.org/PathwayBrowser/#/R-XTR-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Xenopus tropicalis 17411 R-BTA-1678742 https://reactome.org/PathwayBrowser/#/R-BTA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Bos taurus 17411 R-BTA-2090038 https://reactome.org/PathwayBrowser/#/R-BTA-2090038 NAGLU hydrolyses heparan chain(2) IEA Bos taurus 17411 R-BTA-2162225 https://reactome.org/PathwayBrowser/#/R-BTA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Bos taurus 17411 R-BTA-2162226 https://reactome.org/PathwayBrowser/#/R-BTA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Bos taurus 17411 R-BTA-2203480 https://reactome.org/PathwayBrowser/#/R-BTA-2203480 COLEC11 binds ligands IEA Bos taurus 17411 R-BTA-6786421 https://reactome.org/PathwayBrowser/#/R-BTA-6786421 CHIA hydrolyses chitin IEA Bos taurus 17411 R-BTA-6799977 https://reactome.org/PathwayBrowser/#/R-BTA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Bos taurus 17411 R-BTA-6803761 https://reactome.org/PathwayBrowser/#/R-BTA-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Bos taurus 17411 R-BTA-6803771 https://reactome.org/PathwayBrowser/#/R-BTA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Bos taurus 17411 R-BTA-8853710 https://reactome.org/PathwayBrowser/#/R-BTA-8853710 MANBA hydrolyses GlcNAc:Man IEA Bos taurus 17411 R-BTA-9638076 https://reactome.org/PathwayBrowser/#/R-BTA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Bos taurus 17411 R-CEL-1678742 https://reactome.org/PathwayBrowser/#/R-CEL-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Caenorhabditis elegans 17411 R-CEL-2090038 https://reactome.org/PathwayBrowser/#/R-CEL-2090038 NAGLU hydrolyses heparan chain(2) IEA Caenorhabditis elegans 17411 R-CEL-2162225 https://reactome.org/PathwayBrowser/#/R-CEL-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Caenorhabditis elegans 17411 R-CEL-2162226 https://reactome.org/PathwayBrowser/#/R-CEL-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Caenorhabditis elegans 17411 R-CEL-6803771 https://reactome.org/PathwayBrowser/#/R-CEL-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Caenorhabditis elegans 17411 R-CEL-8853710 https://reactome.org/PathwayBrowser/#/R-CEL-8853710 MANBA hydrolyses GlcNAc:Man IEA Caenorhabditis elegans 17411 R-CEL-9638076 https://reactome.org/PathwayBrowser/#/R-CEL-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Caenorhabditis elegans 17411 R-CFA-1678742 https://reactome.org/PathwayBrowser/#/R-CFA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Canis familiaris 17411 R-CFA-2090038 https://reactome.org/PathwayBrowser/#/R-CFA-2090038 NAGLU hydrolyses heparan chain(2) IEA Canis familiaris 17411 R-CFA-2162225 https://reactome.org/PathwayBrowser/#/R-CFA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Canis familiaris 17411 R-CFA-2162226 https://reactome.org/PathwayBrowser/#/R-CFA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Canis familiaris 17411 R-CFA-6786421 https://reactome.org/PathwayBrowser/#/R-CFA-6786421 CHIA hydrolyses chitin IEA Canis familiaris 17411 R-CFA-6799977 https://reactome.org/PathwayBrowser/#/R-CFA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Canis familiaris 17411 R-CFA-6803771 https://reactome.org/PathwayBrowser/#/R-CFA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Canis familiaris 17411 R-CFA-8853710 https://reactome.org/PathwayBrowser/#/R-CFA-8853710 MANBA hydrolyses GlcNAc:Man IEA Canis familiaris 17411 R-CFA-9638076 https://reactome.org/PathwayBrowser/#/R-CFA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Canis familiaris 17411 R-DDI-1678742 https://reactome.org/PathwayBrowser/#/R-DDI-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Dictyostelium discoideum 17411 R-DDI-2090038 https://reactome.org/PathwayBrowser/#/R-DDI-2090038 NAGLU hydrolyses heparan chain(2) IEA Dictyostelium discoideum 17411 R-DDI-2162225 https://reactome.org/PathwayBrowser/#/R-DDI-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Dictyostelium discoideum 17411 R-DDI-8853710 https://reactome.org/PathwayBrowser/#/R-DDI-8853710 MANBA hydrolyses GlcNAc:Man IEA Dictyostelium discoideum 17411 R-DDI-9638076 https://reactome.org/PathwayBrowser/#/R-DDI-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Dictyostelium discoideum 17411 R-DME-1678742 https://reactome.org/PathwayBrowser/#/R-DME-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Drosophila melanogaster 17411 R-DME-2090038 https://reactome.org/PathwayBrowser/#/R-DME-2090038 NAGLU hydrolyses heparan chain(2) IEA Drosophila melanogaster 17411 R-DME-209158 https://reactome.org/PathwayBrowser/#/R-DME-209158 Polymeric PGN bound PGRP-LCx multimerises at the plasma membrane TAS Drosophila melanogaster 17411 R-DME-209167 https://reactome.org/PathwayBrowser/#/R-DME-209167 Phosphorylated REL is cleaved by and dissociates from DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' TAS Drosophila melanogaster 17411 R-DME-209221 https://reactome.org/PathwayBrowser/#/R-DME-209221 Assembly of the PGN:PGRP-LC oligomer receptor 'signalling complex' IEA Drosophila melanogaster 17411 R-DME-209227 https://reactome.org/PathwayBrowser/#/R-DME-209227 Activated Phospho IRD5:KEY dimer phosphorylates REL in the PGN:PGRP-LC oligomer receptor 'signalling complex' TAS Drosophila melanogaster 17411 R-DME-209244 https://reactome.org/PathwayBrowser/#/R-DME-209244 REL binds to DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' TAS Drosophila melanogaster 17411 R-DME-209377 https://reactome.org/PathwayBrowser/#/R-DME-209377 Polymeric PGN binds to PGRP-LCx at the plasma membrane TAS Drosophila melanogaster 17411 R-DME-2162225 https://reactome.org/PathwayBrowser/#/R-DME-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Drosophila melanogaster 17411 R-DME-2162226 https://reactome.org/PathwayBrowser/#/R-DME-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Drosophila melanogaster 17411 R-DME-6786421 https://reactome.org/PathwayBrowser/#/R-DME-6786421 CHIA hydrolyses chitin IEA Drosophila melanogaster 17411 R-DME-6799977 https://reactome.org/PathwayBrowser/#/R-DME-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Drosophila melanogaster 17411 R-DME-6803771 https://reactome.org/PathwayBrowser/#/R-DME-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Drosophila melanogaster 17411 R-DME-8853710 https://reactome.org/PathwayBrowser/#/R-DME-8853710 MANBA hydrolyses GlcNAc:Man IEA Drosophila melanogaster 17411 R-DME-9638076 https://reactome.org/PathwayBrowser/#/R-DME-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Drosophila melanogaster 17411 R-DRE-6799977 https://reactome.org/PathwayBrowser/#/R-DRE-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Danio rerio 17411 R-DRE-8853710 https://reactome.org/PathwayBrowser/#/R-DRE-8853710 MANBA hydrolyses GlcNAc:Man IEA Danio rerio 17411 R-GGA-1678742 https://reactome.org/PathwayBrowser/#/R-GGA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Gallus gallus 17411 R-GGA-2090038 https://reactome.org/PathwayBrowser/#/R-GGA-2090038 NAGLU hydrolyses heparan chain(2) IEA Gallus gallus 17411 R-GGA-2162225 https://reactome.org/PathwayBrowser/#/R-GGA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Gallus gallus 17411 R-GGA-2162226 https://reactome.org/PathwayBrowser/#/R-GGA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Gallus gallus 17411 R-GGA-2203480 https://reactome.org/PathwayBrowser/#/R-GGA-2203480 COLEC11 binds ligands IEA Gallus gallus 17411 R-GGA-6786421 https://reactome.org/PathwayBrowser/#/R-GGA-6786421 CHIA hydrolyses chitin IEA Gallus gallus 17411 R-GGA-6799977 https://reactome.org/PathwayBrowser/#/R-GGA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Gallus gallus 17411 R-GGA-6803771 https://reactome.org/PathwayBrowser/#/R-GGA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Gallus gallus 17411 R-GGA-8853710 https://reactome.org/PathwayBrowser/#/R-GGA-8853710 MANBA hydrolyses GlcNAc:Man IEA Gallus gallus 17411 R-GGA-9638076 https://reactome.org/PathwayBrowser/#/R-GGA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Gallus gallus 17411 R-HSA-1678742 https://reactome.org/PathwayBrowser/#/R-HSA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) TAS Homo sapiens 17411 R-HSA-2090038 https://reactome.org/PathwayBrowser/#/R-HSA-2090038 NAGLU hydrolyses heparan chain(2) TAS Homo sapiens 17411 R-HSA-2162225 https://reactome.org/PathwayBrowser/#/R-HSA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments TAS Homo sapiens 17411 R-HSA-2162226 https://reactome.org/PathwayBrowser/#/R-HSA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc TAS Homo sapiens 17411 R-HSA-2162229 https://reactome.org/PathwayBrowser/#/R-HSA-2162229 The single sugars GlcA and GlcNAc translocate from the lysosome to the cytosol TAS Homo sapiens 17411 R-HSA-2203480 https://reactome.org/PathwayBrowser/#/R-HSA-2203480 COLEC11 binds ligands TAS Homo sapiens 17411 R-HSA-6786421 https://reactome.org/PathwayBrowser/#/R-HSA-6786421 CHIA hydrolyses chitin TAS Homo sapiens 17411 R-HSA-6799977 https://reactome.org/PathwayBrowser/#/R-HSA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan TAS Homo sapiens 17411 R-HSA-6803761 https://reactome.org/PathwayBrowser/#/R-HSA-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc TAS Homo sapiens 17411 R-HSA-6803771 https://reactome.org/PathwayBrowser/#/R-HSA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P TAS Homo sapiens 17411 R-HSA-8853710 https://reactome.org/PathwayBrowser/#/R-HSA-8853710 MANBA hydrolyses GlcNAc:Man TAS Homo sapiens 17411 R-HSA-9638076 https://reactome.org/PathwayBrowser/#/R-HSA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments TAS Homo sapiens 17411 R-MMU-1678742 https://reactome.org/PathwayBrowser/#/R-MMU-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Mus musculus 17411 R-MMU-2090038 https://reactome.org/PathwayBrowser/#/R-MMU-2090038 NAGLU hydrolyses heparan chain(2) IEA Mus musculus 17411 R-MMU-2162225 https://reactome.org/PathwayBrowser/#/R-MMU-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Mus musculus 17411 R-MMU-2162226 https://reactome.org/PathwayBrowser/#/R-MMU-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Mus musculus 17411 R-MMU-2203480 https://reactome.org/PathwayBrowser/#/R-MMU-2203480 COLEC11 binds ligands IEA Mus musculus 17411 R-MMU-6786421 https://reactome.org/PathwayBrowser/#/R-MMU-6786421 CHIA hydrolyses chitin IEA Mus musculus 17411 R-MMU-6799977 https://reactome.org/PathwayBrowser/#/R-MMU-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Mus musculus 17411 R-MMU-6803761 https://reactome.org/PathwayBrowser/#/R-MMU-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Mus musculus 17411 R-MMU-6803771 https://reactome.org/PathwayBrowser/#/R-MMU-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Mus musculus 17411 R-MMU-8853710 https://reactome.org/PathwayBrowser/#/R-MMU-8853710 MANBA hydrolyses GlcNAc:Man IEA Mus musculus 17411 R-MMU-9638076 https://reactome.org/PathwayBrowser/#/R-MMU-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Mus musculus 17411 R-PFA-6786421 https://reactome.org/PathwayBrowser/#/R-PFA-6786421 CHIA hydrolyses chitin IEA Plasmodium falciparum 17411 R-RNO-1678742 https://reactome.org/PathwayBrowser/#/R-RNO-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Rattus norvegicus 17411 R-RNO-2090038 https://reactome.org/PathwayBrowser/#/R-RNO-2090038 NAGLU hydrolyses heparan chain(2) IEA Rattus norvegicus 17411 R-RNO-2162225 https://reactome.org/PathwayBrowser/#/R-RNO-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Rattus norvegicus 17411 R-RNO-2162226 https://reactome.org/PathwayBrowser/#/R-RNO-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Rattus norvegicus 17411 R-RNO-6786421 https://reactome.org/PathwayBrowser/#/R-RNO-6786421 CHIA hydrolyses chitin IEA Rattus norvegicus 17411 R-RNO-6799977 https://reactome.org/PathwayBrowser/#/R-RNO-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Rattus norvegicus 17411 R-RNO-6803761 https://reactome.org/PathwayBrowser/#/R-RNO-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Rattus norvegicus 17411 R-RNO-6803771 https://reactome.org/PathwayBrowser/#/R-RNO-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Rattus norvegicus 17411 R-RNO-8853710 https://reactome.org/PathwayBrowser/#/R-RNO-8853710 MANBA hydrolyses GlcNAc:Man IEA Rattus norvegicus 17411 R-RNO-9638076 https://reactome.org/PathwayBrowser/#/R-RNO-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Rattus norvegicus 17411 R-SCE-6786421 https://reactome.org/PathwayBrowser/#/R-SCE-6786421 CHIA hydrolyses chitin IEA Saccharomyces cerevisiae 17411 R-SSC-1678742 https://reactome.org/PathwayBrowser/#/R-SSC-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Sus scrofa 17411 R-SSC-2090038 https://reactome.org/PathwayBrowser/#/R-SSC-2090038 NAGLU hydrolyses heparan chain(2) IEA Sus scrofa 17411 R-SSC-2162225 https://reactome.org/PathwayBrowser/#/R-SSC-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Sus scrofa 17411 R-SSC-2162226 https://reactome.org/PathwayBrowser/#/R-SSC-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Sus scrofa 17411 R-SSC-2203480 https://reactome.org/PathwayBrowser/#/R-SSC-2203480 COLEC11 binds ligands IEA Sus scrofa 17411 R-SSC-6786421 https://reactome.org/PathwayBrowser/#/R-SSC-6786421 CHIA hydrolyses chitin IEA Sus scrofa 17411 R-SSC-6799977 https://reactome.org/PathwayBrowser/#/R-SSC-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Sus scrofa 17411 R-SSC-6803761 https://reactome.org/PathwayBrowser/#/R-SSC-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Sus scrofa 17411 R-SSC-6803771 https://reactome.org/PathwayBrowser/#/R-SSC-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Sus scrofa 17411 R-SSC-8853710 https://reactome.org/PathwayBrowser/#/R-SSC-8853710 MANBA hydrolyses GlcNAc:Man IEA Sus scrofa 17411 R-SSC-9638076 https://reactome.org/PathwayBrowser/#/R-SSC-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Sus scrofa 17411 R-XTR-2162226 https://reactome.org/PathwayBrowser/#/R-XTR-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Xenopus tropicalis 17411 R-XTR-6799977 https://reactome.org/PathwayBrowser/#/R-XTR-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Xenopus tropicalis 17411 R-XTR-6803761 https://reactome.org/PathwayBrowser/#/R-XTR-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Xenopus tropicalis 17411 R-XTR-8853710 https://reactome.org/PathwayBrowser/#/R-XTR-8853710 MANBA hydrolyses GlcNAc:Man IEA Xenopus tropicalis 17411 R-XTR-9638076 https://reactome.org/PathwayBrowser/#/R-XTR-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Xenopus tropicalis 17433 R-HSA-6782443 https://reactome.org/PathwayBrowser/#/R-HSA-6782443 QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr) TAS Homo sapiens 17439 R-BTA-3149519 https://reactome.org/PathwayBrowser/#/R-BTA-3149519 MMACHC decyanates CNCbl IEA Bos taurus 17439 R-CEL-3149519 https://reactome.org/PathwayBrowser/#/R-CEL-3149519 MMACHC decyanates CNCbl IEA Caenorhabditis elegans 17439 R-CFA-3149519 https://reactome.org/PathwayBrowser/#/R-CFA-3149519 MMACHC decyanates CNCbl IEA Canis familiaris 17439 R-DDI-3149519 https://reactome.org/PathwayBrowser/#/R-DDI-3149519 MMACHC decyanates CNCbl IEA Dictyostelium discoideum 17439 R-DRE-3149519 https://reactome.org/PathwayBrowser/#/R-DRE-3149519 MMACHC decyanates CNCbl IEA Danio rerio 17439 R-GGA-3149519 https://reactome.org/PathwayBrowser/#/R-GGA-3149519 MMACHC decyanates CNCbl IEA Gallus gallus 17439 R-HSA-3149519 https://reactome.org/PathwayBrowser/#/R-HSA-3149519 MMACHC decyanates CNCbl TAS Homo sapiens 17439 R-HSA-3318590 https://reactome.org/PathwayBrowser/#/R-HSA-3318590 Defective MMACHC does not decyanate CNCbl TAS Homo sapiens 17439 R-MMU-3149519 https://reactome.org/PathwayBrowser/#/R-MMU-3149519 MMACHC decyanates CNCbl IEA Mus musculus 17439 R-RNO-3149519 https://reactome.org/PathwayBrowser/#/R-RNO-3149519 MMACHC decyanates CNCbl IEA Rattus norvegicus 17439 R-SSC-3149519 https://reactome.org/PathwayBrowser/#/R-SSC-3149519 MMACHC decyanates CNCbl IEA Sus scrofa 17439 R-XTR-3149519 https://reactome.org/PathwayBrowser/#/R-XTR-3149519 MMACHC decyanates CNCbl IEA Xenopus tropicalis 17442 R-BTA-893583 https://reactome.org/PathwayBrowser/#/R-BTA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Bos taurus 17442 R-BTA-893596 https://reactome.org/PathwayBrowser/#/R-BTA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Bos taurus 17442 R-CEL-893596 https://reactome.org/PathwayBrowser/#/R-CEL-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Caenorhabditis elegans 17442 R-CFA-893583 https://reactome.org/PathwayBrowser/#/R-CFA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Canis familiaris 17442 R-CFA-893596 https://reactome.org/PathwayBrowser/#/R-CFA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Canis familiaris 17442 R-DDI-893583 https://reactome.org/PathwayBrowser/#/R-DDI-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Dictyostelium discoideum 17442 R-DDI-893596 https://reactome.org/PathwayBrowser/#/R-DDI-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Dictyostelium discoideum 17442 R-DME-893596 https://reactome.org/PathwayBrowser/#/R-DME-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Drosophila melanogaster 17442 R-DRE-893596 https://reactome.org/PathwayBrowser/#/R-DRE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Danio rerio 17442 R-GGA-893583 https://reactome.org/PathwayBrowser/#/R-GGA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Gallus gallus 17442 R-GGA-893596 https://reactome.org/PathwayBrowser/#/R-GGA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Gallus gallus 17442 R-HSA-893583 https://reactome.org/PathwayBrowser/#/R-HSA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate TAS Homo sapiens 17442 R-HSA-893596 https://reactome.org/PathwayBrowser/#/R-HSA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu TAS Homo sapiens 17442 R-HSA-893597 https://reactome.org/PathwayBrowser/#/R-HSA-893597 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [mitochondrial] TAS Homo sapiens 17442 R-HSA-893609 https://reactome.org/PathwayBrowser/#/R-HSA-893609 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [cytosolic] TAS Homo sapiens 17442 R-HSA-901097 https://reactome.org/PathwayBrowser/#/R-HSA-901097 kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2] IEA Homo sapiens 17442 R-MMU-893583 https://reactome.org/PathwayBrowser/#/R-MMU-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Mus musculus 17442 R-MMU-893596 https://reactome.org/PathwayBrowser/#/R-MMU-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Mus musculus 17442 R-RNO-893583 https://reactome.org/PathwayBrowser/#/R-RNO-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Rattus norvegicus 17442 R-RNO-893596 https://reactome.org/PathwayBrowser/#/R-RNO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Rattus norvegicus 17442 R-SCE-893583 https://reactome.org/PathwayBrowser/#/R-SCE-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Saccharomyces cerevisiae 17442 R-SCE-893596 https://reactome.org/PathwayBrowser/#/R-SCE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Saccharomyces cerevisiae 17442 R-SPO-893583 https://reactome.org/PathwayBrowser/#/R-SPO-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Schizosaccharomyces pombe 17442 R-SPO-893596 https://reactome.org/PathwayBrowser/#/R-SPO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Schizosaccharomyces pombe 17442 R-SSC-893583 https://reactome.org/PathwayBrowser/#/R-SSC-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Sus scrofa 17442 R-SSC-893596 https://reactome.org/PathwayBrowser/#/R-SSC-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Sus scrofa 17442 R-XTR-893583 https://reactome.org/PathwayBrowser/#/R-XTR-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Xenopus tropicalis 17442 R-XTR-893596 https://reactome.org/PathwayBrowser/#/R-XTR-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Xenopus tropicalis 17447 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 17447 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 17447 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 17447 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 17447 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 17447 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 17447 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 17447 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 17447 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 17474 R-BTA-176664 https://reactome.org/PathwayBrowser/#/R-BTA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Bos taurus 17474 R-BTA-561059 https://reactome.org/PathwayBrowser/#/R-BTA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Bos taurus 17474 R-BTA-879562 https://reactome.org/PathwayBrowser/#/R-BTA-879562 SLCO2B1 has a narrow substrate specificity IEA Bos taurus 17474 R-CEL-561059 https://reactome.org/PathwayBrowser/#/R-CEL-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Caenorhabditis elegans 17474 R-CEL-879562 https://reactome.org/PathwayBrowser/#/R-CEL-879562 SLCO2B1 has a narrow substrate specificity IEA Caenorhabditis elegans 17474 R-CFA-176664 https://reactome.org/PathwayBrowser/#/R-CFA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Canis familiaris 17474 R-CFA-561059 https://reactome.org/PathwayBrowser/#/R-CFA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Canis familiaris 17474 R-CFA-879562 https://reactome.org/PathwayBrowser/#/R-CFA-879562 SLCO2B1 has a narrow substrate specificity IEA Canis familiaris 17474 R-DME-176664 https://reactome.org/PathwayBrowser/#/R-DME-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Drosophila melanogaster 17474 R-DME-561059 https://reactome.org/PathwayBrowser/#/R-DME-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Drosophila melanogaster 17474 R-DME-879562 https://reactome.org/PathwayBrowser/#/R-DME-879562 SLCO2B1 has a narrow substrate specificity IEA Drosophila melanogaster 17474 R-DRE-176664 https://reactome.org/PathwayBrowser/#/R-DRE-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Danio rerio 17474 R-DRE-561059 https://reactome.org/PathwayBrowser/#/R-DRE-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Danio rerio 17474 R-DRE-879562 https://reactome.org/PathwayBrowser/#/R-DRE-879562 SLCO2B1 has a narrow substrate specificity IEA Danio rerio 17474 R-GGA-176664 https://reactome.org/PathwayBrowser/#/R-GGA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Gallus gallus 17474 R-GGA-561059 https://reactome.org/PathwayBrowser/#/R-GGA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Gallus gallus 17474 R-GGA-879562 https://reactome.org/PathwayBrowser/#/R-GGA-879562 SLCO2B1 has a narrow substrate specificity IEA Gallus gallus 17474 R-HSA-176664 https://reactome.org/PathwayBrowser/#/R-HSA-176664 estrone + PAPS => estrone 3-sulfate + PAP TAS Homo sapiens 17474 R-HSA-561059 https://reactome.org/PathwayBrowser/#/R-HSA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates TAS Homo sapiens 17474 R-HSA-879562 https://reactome.org/PathwayBrowser/#/R-HSA-879562 SLCO2B1 has a narrow substrate specificity TAS Homo sapiens 17474 R-MMU-176664 https://reactome.org/PathwayBrowser/#/R-MMU-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Mus musculus 17474 R-MMU-561059 https://reactome.org/PathwayBrowser/#/R-MMU-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Mus musculus 17474 R-MMU-879562 https://reactome.org/PathwayBrowser/#/R-MMU-879562 SLCO2B1 has a narrow substrate specificity IEA Mus musculus 17474 R-RNO-176664 https://reactome.org/PathwayBrowser/#/R-RNO-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Rattus norvegicus 17474 R-RNO-561059 https://reactome.org/PathwayBrowser/#/R-RNO-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Rattus norvegicus 17474 R-RNO-879562 https://reactome.org/PathwayBrowser/#/R-RNO-879562 SLCO2B1 has a narrow substrate specificity IEA Rattus norvegicus 17474 R-SSC-176664 https://reactome.org/PathwayBrowser/#/R-SSC-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Sus scrofa 17474 R-SSC-561059 https://reactome.org/PathwayBrowser/#/R-SSC-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Sus scrofa 17474 R-SSC-879562 https://reactome.org/PathwayBrowser/#/R-SSC-879562 SLCO2B1 has a narrow substrate specificity IEA Sus scrofa 17474 R-XTR-176664 https://reactome.org/PathwayBrowser/#/R-XTR-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Xenopus tropicalis 17474 R-XTR-879562 https://reactome.org/PathwayBrowser/#/R-XTR-879562 SLCO2B1 has a narrow substrate specificity IEA Xenopus tropicalis 17476 R-BTA-8874435 https://reactome.org/PathwayBrowser/#/R-BTA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Bos taurus 17476 R-CEL-8874435 https://reactome.org/PathwayBrowser/#/R-CEL-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Caenorhabditis elegans 17476 R-CFA-8874435 https://reactome.org/PathwayBrowser/#/R-CFA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Canis familiaris 17476 R-DDI-8874435 https://reactome.org/PathwayBrowser/#/R-DDI-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Dictyostelium discoideum 17476 R-DME-8874435 https://reactome.org/PathwayBrowser/#/R-DME-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Drosophila melanogaster 17476 R-DRE-8874435 https://reactome.org/PathwayBrowser/#/R-DRE-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Danio rerio 17476 R-HSA-8874435 https://reactome.org/PathwayBrowser/#/R-HSA-8874435 THEM86B hydrolyses PMCHO, PMETAM TAS Homo sapiens 17476 R-MMU-8874435 https://reactome.org/PathwayBrowser/#/R-MMU-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Mus musculus 17476 R-RNO-8874435 https://reactome.org/PathwayBrowser/#/R-RNO-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Rattus norvegicus 17476 R-SSC-8874435 https://reactome.org/PathwayBrowser/#/R-SSC-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Sus scrofa 17476 R-XTR-8874435 https://reactome.org/PathwayBrowser/#/R-XTR-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Xenopus tropicalis 17482 R-BTA-1614524 https://reactome.org/PathwayBrowser/#/R-BTA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Bos taurus 17482 R-BTA-1614583 https://reactome.org/PathwayBrowser/#/R-BTA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Bos taurus 17482 R-CEL-1614524 https://reactome.org/PathwayBrowser/#/R-CEL-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Caenorhabditis elegans 17482 R-CEL-1614583 https://reactome.org/PathwayBrowser/#/R-CEL-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Caenorhabditis elegans 17482 R-CFA-1614524 https://reactome.org/PathwayBrowser/#/R-CFA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Canis familiaris 17482 R-CFA-1614583 https://reactome.org/PathwayBrowser/#/R-CFA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Canis familiaris 17482 R-DDI-1614524 https://reactome.org/PathwayBrowser/#/R-DDI-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Dictyostelium discoideum 17482 R-DDI-1614583 https://reactome.org/PathwayBrowser/#/R-DDI-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Dictyostelium discoideum 17482 R-DME-1614524 https://reactome.org/PathwayBrowser/#/R-DME-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Drosophila melanogaster 17482 R-DME-1614583 https://reactome.org/PathwayBrowser/#/R-DME-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Drosophila melanogaster 17482 R-DRE-1614524 https://reactome.org/PathwayBrowser/#/R-DRE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Danio rerio 17482 R-DRE-1614583 https://reactome.org/PathwayBrowser/#/R-DRE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Danio rerio 17482 R-GGA-1614524 https://reactome.org/PathwayBrowser/#/R-GGA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Gallus gallus 17482 R-GGA-1614583 https://reactome.org/PathwayBrowser/#/R-GGA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Gallus gallus 17482 R-HSA-1614524 https://reactome.org/PathwayBrowser/#/R-HSA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine TAS Homo sapiens 17482 R-HSA-1614583 https://reactome.org/PathwayBrowser/#/R-HSA-1614583 PXLP-K212-CTH cleaves L-Cystathionine TAS Homo sapiens 17482 R-MMU-1614524 https://reactome.org/PathwayBrowser/#/R-MMU-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Mus musculus 17482 R-MMU-1614583 https://reactome.org/PathwayBrowser/#/R-MMU-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Mus musculus 17482 R-RNO-1614524 https://reactome.org/PathwayBrowser/#/R-RNO-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Rattus norvegicus 17482 R-RNO-1614583 https://reactome.org/PathwayBrowser/#/R-RNO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Rattus norvegicus 17482 R-SCE-1614524 https://reactome.org/PathwayBrowser/#/R-SCE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Saccharomyces cerevisiae 17482 R-SCE-1614583 https://reactome.org/PathwayBrowser/#/R-SCE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Saccharomyces cerevisiae 17482 R-SPO-1614583 https://reactome.org/PathwayBrowser/#/R-SPO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Schizosaccharomyces pombe 17482 R-SSC-1614524 https://reactome.org/PathwayBrowser/#/R-SSC-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Sus scrofa 17482 R-SSC-1614583 https://reactome.org/PathwayBrowser/#/R-SSC-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Sus scrofa 17482 R-XTR-1614583 https://reactome.org/PathwayBrowser/#/R-XTR-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Xenopus tropicalis 17490 R-BTA-200406 https://reactome.org/PathwayBrowser/#/R-BTA-200406 CPT1A,B transfers PALM to CAR IEA Bos taurus 17490 R-BTA-200410 https://reactome.org/PathwayBrowser/#/R-BTA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Bos taurus 17490 R-BTA-200424 https://reactome.org/PathwayBrowser/#/R-BTA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Bos taurus 17490 R-CEL-200406 https://reactome.org/PathwayBrowser/#/R-CEL-200406 CPT1A,B transfers PALM to CAR IEA Caenorhabditis elegans 17490 R-CEL-200410 https://reactome.org/PathwayBrowser/#/R-CEL-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Caenorhabditis elegans 17490 R-CEL-200424 https://reactome.org/PathwayBrowser/#/R-CEL-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Caenorhabditis elegans 17490 R-CFA-200406 https://reactome.org/PathwayBrowser/#/R-CFA-200406 CPT1A,B transfers PALM to CAR IEA Canis familiaris 17490 R-CFA-200410 https://reactome.org/PathwayBrowser/#/R-CFA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Canis familiaris 17490 R-CFA-200424 https://reactome.org/PathwayBrowser/#/R-CFA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Canis familiaris 17490 R-DME-200406 https://reactome.org/PathwayBrowser/#/R-DME-200406 CPT1A,B transfers PALM to CAR IEA Drosophila melanogaster 17490 R-DME-200410 https://reactome.org/PathwayBrowser/#/R-DME-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Drosophila melanogaster 17490 R-DME-200424 https://reactome.org/PathwayBrowser/#/R-DME-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Drosophila melanogaster 17490 R-DRE-200406 https://reactome.org/PathwayBrowser/#/R-DRE-200406 CPT1A,B transfers PALM to CAR IEA Danio rerio 17490 R-DRE-200410 https://reactome.org/PathwayBrowser/#/R-DRE-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Danio rerio 17490 R-DRE-200424 https://reactome.org/PathwayBrowser/#/R-DRE-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Danio rerio 17490 R-GGA-200406 https://reactome.org/PathwayBrowser/#/R-GGA-200406 CPT1A,B transfers PALM to CAR IEA Gallus gallus 17490 R-GGA-200410 https://reactome.org/PathwayBrowser/#/R-GGA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Gallus gallus 17490 R-GGA-200424 https://reactome.org/PathwayBrowser/#/R-GGA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Gallus gallus 17490 R-HSA-200406 https://reactome.org/PathwayBrowser/#/R-HSA-200406 CPT1A,B transfers PALM to CAR TAS Homo sapiens 17490 R-HSA-200410 https://reactome.org/PathwayBrowser/#/R-HSA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine TAS Homo sapiens 17490 R-HSA-200424 https://reactome.org/PathwayBrowser/#/R-HSA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane TAS Homo sapiens 17490 R-MMU-200406 https://reactome.org/PathwayBrowser/#/R-MMU-200406 CPT1A,B transfers PALM to CAR IEA Mus musculus 17490 R-MMU-200410 https://reactome.org/PathwayBrowser/#/R-MMU-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Mus musculus 17490 R-MMU-200424 https://reactome.org/PathwayBrowser/#/R-MMU-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Mus musculus 17490 R-RNO-200406 https://reactome.org/PathwayBrowser/#/R-RNO-200406 CPT1A,B transfers PALM to CAR IEA Rattus norvegicus 17490 R-RNO-200410 https://reactome.org/PathwayBrowser/#/R-RNO-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Rattus norvegicus 17490 R-RNO-200424 https://reactome.org/PathwayBrowser/#/R-RNO-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Rattus norvegicus 17490 R-SCE-200424 https://reactome.org/PathwayBrowser/#/R-SCE-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Saccharomyces cerevisiae 17490 R-SPO-200424 https://reactome.org/PathwayBrowser/#/R-SPO-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Schizosaccharomyces pombe 17490 R-SSC-200406 https://reactome.org/PathwayBrowser/#/R-SSC-200406 CPT1A,B transfers PALM to CAR IEA Sus scrofa 17490 R-SSC-200410 https://reactome.org/PathwayBrowser/#/R-SSC-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Sus scrofa 17490 R-SSC-200424 https://reactome.org/PathwayBrowser/#/R-SSC-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Sus scrofa 17490 R-XTR-200406 https://reactome.org/PathwayBrowser/#/R-XTR-200406 CPT1A,B transfers PALM to CAR IEA Xenopus tropicalis 17490 R-XTR-200410 https://reactome.org/PathwayBrowser/#/R-XTR-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Xenopus tropicalis 17490 R-XTR-200424 https://reactome.org/PathwayBrowser/#/R-XTR-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Xenopus tropicalis 17499 R-BTA-2995334 https://reactome.org/PathwayBrowser/#/R-BTA-2995334 COX15 transforms heme O to heme A IEA Bos taurus 17499 R-BTA-6797961 https://reactome.org/PathwayBrowser/#/R-BTA-6797961 CHDH oxidises Cho to BETALD IEA Bos taurus 17499 R-CEL-2995334 https://reactome.org/PathwayBrowser/#/R-CEL-2995334 COX15 transforms heme O to heme A IEA Caenorhabditis elegans 17499 R-CEL-6797961 https://reactome.org/PathwayBrowser/#/R-CEL-6797961 CHDH oxidises Cho to BETALD IEA Caenorhabditis elegans 17499 R-CFA-2995334 https://reactome.org/PathwayBrowser/#/R-CFA-2995334 COX15 transforms heme O to heme A IEA Canis familiaris 17499 R-CFA-6797961 https://reactome.org/PathwayBrowser/#/R-CFA-6797961 CHDH oxidises Cho to BETALD IEA Canis familiaris 17499 R-DDI-2995334 https://reactome.org/PathwayBrowser/#/R-DDI-2995334 COX15 transforms heme O to heme A IEA Dictyostelium discoideum 17499 R-DDI-6797961 https://reactome.org/PathwayBrowser/#/R-DDI-6797961 CHDH oxidises Cho to BETALD IEA Dictyostelium discoideum 17499 R-DME-2995334 https://reactome.org/PathwayBrowser/#/R-DME-2995334 COX15 transforms heme O to heme A IEA Drosophila melanogaster 17499 R-DME-6797961 https://reactome.org/PathwayBrowser/#/R-DME-6797961 CHDH oxidises Cho to BETALD IEA Drosophila melanogaster 17499 R-GGA-2995334 https://reactome.org/PathwayBrowser/#/R-GGA-2995334 COX15 transforms heme O to heme A IEA Gallus gallus 17499 R-GGA-6797961 https://reactome.org/PathwayBrowser/#/R-GGA-6797961 CHDH oxidises Cho to BETALD IEA Gallus gallus 17499 R-HSA-2995334 https://reactome.org/PathwayBrowser/#/R-HSA-2995334 COX15 transforms heme O to heme A TAS Homo sapiens 17499 R-HSA-6797961 https://reactome.org/PathwayBrowser/#/R-HSA-6797961 CHDH oxidises Cho to BETALD TAS Homo sapiens 17499 R-MMU-2995334 https://reactome.org/PathwayBrowser/#/R-MMU-2995334 COX15 transforms heme O to heme A IEA Mus musculus 17499 R-MMU-6797961 https://reactome.org/PathwayBrowser/#/R-MMU-6797961 CHDH oxidises Cho to BETALD IEA Mus musculus 17499 R-PFA-2995334 https://reactome.org/PathwayBrowser/#/R-PFA-2995334 COX15 transforms heme O to heme A IEA Plasmodium falciparum 17499 R-RNO-2995334 https://reactome.org/PathwayBrowser/#/R-RNO-2995334 COX15 transforms heme O to heme A IEA Rattus norvegicus 17499 R-RNO-6797961 https://reactome.org/PathwayBrowser/#/R-RNO-6797961 CHDH oxidises Cho to BETALD IEA Rattus norvegicus 17499 R-SCE-2995334 https://reactome.org/PathwayBrowser/#/R-SCE-2995334 COX15 transforms heme O to heme A IEA Saccharomyces cerevisiae 17499 R-SPO-2995334 https://reactome.org/PathwayBrowser/#/R-SPO-2995334 COX15 transforms heme O to heme A IEA Schizosaccharomyces pombe 17499 R-SSC-2995334 https://reactome.org/PathwayBrowser/#/R-SSC-2995334 COX15 transforms heme O to heme A IEA Sus scrofa 17499 R-SSC-6797961 https://reactome.org/PathwayBrowser/#/R-SSC-6797961 CHDH oxidises Cho to BETALD IEA Sus scrofa 17499 R-XTR-2995334 https://reactome.org/PathwayBrowser/#/R-XTR-2995334 COX15 transforms heme O to heme A IEA Xenopus tropicalis 17500 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 17500 R-BTA-192097 https://reactome.org/PathwayBrowser/#/R-BTA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Bos taurus 17500 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 17500 R-CFA-192097 https://reactome.org/PathwayBrowser/#/R-CFA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Canis familiaris 17500 R-DRE-192097 https://reactome.org/PathwayBrowser/#/R-DRE-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Danio rerio 17500 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 17500 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 17500 R-HSA-192097 https://reactome.org/PathwayBrowser/#/R-HSA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one TAS Homo sapiens 17500 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 17500 R-MMU-192097 https://reactome.org/PathwayBrowser/#/R-MMU-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Mus musculus 17500 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 17500 R-RNO-192097 https://reactome.org/PathwayBrowser/#/R-RNO-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Rattus norvegicus 17500 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 17500 R-SSC-192097 https://reactome.org/PathwayBrowser/#/R-SSC-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Sus scrofa 17500 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 17500 R-XTR-192097 https://reactome.org/PathwayBrowser/#/R-XTR-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Xenopus tropicalis 17504 R-BTA-111883 https://reactome.org/PathwayBrowser/#/R-BTA-111883 Hydrolysis of phosphatidylcholine IEA Bos taurus 17504 R-BTA-1482547 https://reactome.org/PathwayBrowser/#/R-BTA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Bos taurus 17504 R-BTA-1482685 https://reactome.org/PathwayBrowser/#/R-BTA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 17504 R-BTA-1482781 https://reactome.org/PathwayBrowser/#/R-BTA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Bos taurus 17504 R-BTA-1482794 https://reactome.org/PathwayBrowser/#/R-BTA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Bos taurus 17504 R-BTA-1482816 https://reactome.org/PathwayBrowser/#/R-BTA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Bos taurus 17504 R-BTA-1482856 https://reactome.org/PathwayBrowser/#/R-BTA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Bos taurus 17504 R-BTA-1602399 https://reactome.org/PathwayBrowser/#/R-BTA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Bos taurus 17504 R-BTA-1602417 https://reactome.org/PathwayBrowser/#/R-BTA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Bos taurus 17504 R-BTA-2029475 https://reactome.org/PathwayBrowser/#/R-BTA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Bos taurus 17504 R-BTA-264679 https://reactome.org/PathwayBrowser/#/R-BTA-264679 Serum albumin binds 2-lysophosphatidylcholine IEA Bos taurus 17504 R-BTA-264695 https://reactome.org/PathwayBrowser/#/R-BTA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Bos taurus 17504 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 17504 R-BTA-400509 https://reactome.org/PathwayBrowser/#/R-BTA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Bos taurus 17504 R-BTA-8848484 https://reactome.org/PathwayBrowser/#/R-BTA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Bos taurus 17504 R-BTA-8849345 https://reactome.org/PathwayBrowser/#/R-BTA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Bos taurus 17504 R-BTA-8849353 https://reactome.org/PathwayBrowser/#/R-BTA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Bos taurus 17504 R-CEL-1482547 https://reactome.org/PathwayBrowser/#/R-CEL-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Caenorhabditis elegans 17504 R-CEL-1482781 https://reactome.org/PathwayBrowser/#/R-CEL-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 17504 R-CEL-1482794 https://reactome.org/PathwayBrowser/#/R-CEL-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 17504 R-CEL-1482816 https://reactome.org/PathwayBrowser/#/R-CEL-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Caenorhabditis elegans 17504 R-CEL-1482856 https://reactome.org/PathwayBrowser/#/R-CEL-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Caenorhabditis elegans 17504 R-CEL-1602399 https://reactome.org/PathwayBrowser/#/R-CEL-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Caenorhabditis elegans 17504 R-CEL-1602417 https://reactome.org/PathwayBrowser/#/R-CEL-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Caenorhabditis elegans 17504 R-CEL-2029475 https://reactome.org/PathwayBrowser/#/R-CEL-2029475 Production of AA by iPLA2 upon FCGR activation IEA Caenorhabditis elegans 17504 R-CEL-264695 https://reactome.org/PathwayBrowser/#/R-CEL-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Caenorhabditis elegans 17504 R-CEL-8848484 https://reactome.org/PathwayBrowser/#/R-CEL-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Caenorhabditis elegans 17504 R-CEL-8849353 https://reactome.org/PathwayBrowser/#/R-CEL-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Caenorhabditis elegans 17504 R-CFA-111883 https://reactome.org/PathwayBrowser/#/R-CFA-111883 Hydrolysis of phosphatidylcholine IEA Canis familiaris 17504 R-CFA-1482547 https://reactome.org/PathwayBrowser/#/R-CFA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Canis familiaris 17504 R-CFA-1482685 https://reactome.org/PathwayBrowser/#/R-CFA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 17504 R-CFA-1482781 https://reactome.org/PathwayBrowser/#/R-CFA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Canis familiaris 17504 R-CFA-1482794 https://reactome.org/PathwayBrowser/#/R-CFA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Canis familiaris 17504 R-CFA-1482816 https://reactome.org/PathwayBrowser/#/R-CFA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Canis familiaris 17504 R-CFA-1482856 https://reactome.org/PathwayBrowser/#/R-CFA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Canis familiaris 17504 R-CFA-1602399 https://reactome.org/PathwayBrowser/#/R-CFA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Canis familiaris 17504 R-CFA-1602417 https://reactome.org/PathwayBrowser/#/R-CFA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Canis familiaris 17504 R-CFA-2029475 https://reactome.org/PathwayBrowser/#/R-CFA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Canis familiaris 17504 R-CFA-264679 https://reactome.org/PathwayBrowser/#/R-CFA-264679 Serum albumin binds 2-lysophosphatidylcholine IEA Canis familiaris 17504 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 17504 R-CFA-400509 https://reactome.org/PathwayBrowser/#/R-CFA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Canis familiaris 17504 R-CFA-8848484 https://reactome.org/PathwayBrowser/#/R-CFA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Canis familiaris 17504 R-CFA-8849345 https://reactome.org/PathwayBrowser/#/R-CFA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Canis familiaris 17504 R-DDI-1482547 https://reactome.org/PathwayBrowser/#/R-DDI-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Dictyostelium discoideum 17504 R-DDI-1482685 https://reactome.org/PathwayBrowser/#/R-DDI-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Dictyostelium discoideum 17504 R-DDI-1482781 https://reactome.org/PathwayBrowser/#/R-DDI-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 17504 R-DDI-1482794 https://reactome.org/PathwayBrowser/#/R-DDI-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 17504 R-DDI-1482816 https://reactome.org/PathwayBrowser/#/R-DDI-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Dictyostelium discoideum 17504 R-DDI-1482856 https://reactome.org/PathwayBrowser/#/R-DDI-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Dictyostelium discoideum 17504 R-DME-1482547 https://reactome.org/PathwayBrowser/#/R-DME-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Drosophila melanogaster 17504 R-DME-1482781 https://reactome.org/PathwayBrowser/#/R-DME-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Drosophila melanogaster 17504 R-DME-1482794 https://reactome.org/PathwayBrowser/#/R-DME-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Drosophila melanogaster 17504 R-DME-1482816 https://reactome.org/PathwayBrowser/#/R-DME-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Drosophila melanogaster 17504 R-DME-1482856 https://reactome.org/PathwayBrowser/#/R-DME-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Drosophila melanogaster 17504 R-DME-1602399 https://reactome.org/PathwayBrowser/#/R-DME-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Drosophila melanogaster 17504 R-DME-1602417 https://reactome.org/PathwayBrowser/#/R-DME-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Drosophila melanogaster 17504 R-DME-2029475 https://reactome.org/PathwayBrowser/#/R-DME-2029475 Production of AA by iPLA2 upon FCGR activation IEA Drosophila melanogaster 17504 R-DME-264695 https://reactome.org/PathwayBrowser/#/R-DME-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Drosophila melanogaster 17504 R-DME-8848484 https://reactome.org/PathwayBrowser/#/R-DME-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Drosophila melanogaster 17504 R-DME-8849345 https://reactome.org/PathwayBrowser/#/R-DME-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Drosophila melanogaster 17504 R-DME-8849353 https://reactome.org/PathwayBrowser/#/R-DME-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Drosophila melanogaster 17504 R-DRE-111883 https://reactome.org/PathwayBrowser/#/R-DRE-111883 Hydrolysis of phosphatidylcholine IEA Danio rerio 17504 R-DRE-1482547 https://reactome.org/PathwayBrowser/#/R-DRE-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Danio rerio 17504 R-DRE-1482685 https://reactome.org/PathwayBrowser/#/R-DRE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 17504 R-DRE-1482696 https://reactome.org/PathwayBrowser/#/R-DRE-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Danio rerio 17504 R-DRE-1482781 https://reactome.org/PathwayBrowser/#/R-DRE-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Danio rerio 17504 R-DRE-1482794 https://reactome.org/PathwayBrowser/#/R-DRE-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Danio rerio 17504 R-DRE-1482816 https://reactome.org/PathwayBrowser/#/R-DRE-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Danio rerio 17504 R-DRE-1482856 https://reactome.org/PathwayBrowser/#/R-DRE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Danio rerio 17504 R-DRE-1602417 https://reactome.org/PathwayBrowser/#/R-DRE-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Danio rerio 17504 R-DRE-8848484 https://reactome.org/PathwayBrowser/#/R-DRE-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Danio rerio 17504 R-DRE-8849345 https://reactome.org/PathwayBrowser/#/R-DRE-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Danio rerio 17504 R-GGA-111883 https://reactome.org/PathwayBrowser/#/R-GGA-111883 Hydrolysis of phosphatidylcholine IEA Gallus gallus 17504 R-GGA-1482547 https://reactome.org/PathwayBrowser/#/R-GGA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus 17504 R-GGA-1482685 https://reactome.org/PathwayBrowser/#/R-GGA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 17504 R-GGA-1482781 https://reactome.org/PathwayBrowser/#/R-GGA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Gallus gallus 17504 R-GGA-1482794 https://reactome.org/PathwayBrowser/#/R-GGA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Gallus gallus 17504 R-GGA-1482816 https://reactome.org/PathwayBrowser/#/R-GGA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Gallus gallus 17504 R-GGA-1482856 https://reactome.org/PathwayBrowser/#/R-GGA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Gallus gallus 17504 R-GGA-1602399 https://reactome.org/PathwayBrowser/#/R-GGA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Gallus gallus 17504 R-GGA-1602417 https://reactome.org/PathwayBrowser/#/R-GGA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Gallus gallus 17504 R-GGA-2029475 https://reactome.org/PathwayBrowser/#/R-GGA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Gallus gallus 17504 R-GGA-264679 https://reactome.org/PathwayBrowser/#/R-GGA-264679 Serum albumin binds 2-lysophosphatidylcholine IEA Gallus gallus 17504 R-GGA-264695 https://reactome.org/PathwayBrowser/#/R-GGA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Gallus gallus 17504 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 17504 R-GGA-400509 https://reactome.org/PathwayBrowser/#/R-GGA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Gallus gallus 17504 R-GGA-8848484 https://reactome.org/PathwayBrowser/#/R-GGA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Gallus gallus 17504 R-GGA-8849345 https://reactome.org/PathwayBrowser/#/R-GGA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Gallus gallus 17504 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus 17504 R-HSA-111883 https://reactome.org/PathwayBrowser/#/R-HSA-111883 Hydrolysis of phosphatidylcholine TAS Homo sapiens 17504 R-HSA-1482547 https://reactome.org/PathwayBrowser/#/R-HSA-1482547 1-acyl LPC is acylated to PC by LPCAT TAS Homo sapiens 17504 R-HSA-1482685 https://reactome.org/PathwayBrowser/#/R-HSA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 17504 R-HSA-1482696 https://reactome.org/PathwayBrowser/#/R-HSA-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C TAS Homo sapiens 17504 R-HSA-1482781 https://reactome.org/PathwayBrowser/#/R-HSA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) TAS Homo sapiens 17504 R-HSA-1482794 https://reactome.org/PathwayBrowser/#/R-HSA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) TAS Homo sapiens 17504 R-HSA-1482816 https://reactome.org/PathwayBrowser/#/R-HSA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] TAS Homo sapiens 17504 R-HSA-1482856 https://reactome.org/PathwayBrowser/#/R-HSA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] TAS Homo sapiens 17504 R-HSA-1602399 https://reactome.org/PathwayBrowser/#/R-HSA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 TAS Homo sapiens 17504 R-HSA-1602417 https://reactome.org/PathwayBrowser/#/R-HSA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] TAS Homo sapiens 17504 R-HSA-2029475 https://reactome.org/PathwayBrowser/#/R-HSA-2029475 Production of AA by iPLA2 upon FCGR activation TAS Homo sapiens 17504 R-HSA-264679 https://reactome.org/PathwayBrowser/#/R-HSA-264679 Serum albumin binds 2-lysophosphatidylcholine TAS Homo sapiens 17504 R-HSA-264695 https://reactome.org/PathwayBrowser/#/R-HSA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) TAS Homo sapiens 17504 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 17504 R-HSA-400509 https://reactome.org/PathwayBrowser/#/R-HSA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells TAS Homo sapiens 17504 R-HSA-8848484 https://reactome.org/PathwayBrowser/#/R-HSA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane TAS Homo sapiens 17504 R-HSA-8849345 https://reactome.org/PathwayBrowser/#/R-HSA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine TAS Homo sapiens 17504 R-HSA-8849353 https://reactome.org/PathwayBrowser/#/R-HSA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER TAS Homo sapiens 17504 R-MMU-111883 https://reactome.org/PathwayBrowser/#/R-MMU-111883 Hydrolysis of phosphatidylcholine IEA Mus musculus 17504 R-MMU-1482547 https://reactome.org/PathwayBrowser/#/R-MMU-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Mus musculus 17504 R-MMU-1482685 https://reactome.org/PathwayBrowser/#/R-MMU-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 17504 R-MMU-1482696 https://reactome.org/PathwayBrowser/#/R-MMU-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Mus musculus 17504 R-MMU-1482781 https://reactome.org/PathwayBrowser/#/R-MMU-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Mus musculus 17504 R-MMU-1482794 https://reactome.org/PathwayBrowser/#/R-MMU-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Mus musculus 17504 R-MMU-1482816 https://reactome.org/PathwayBrowser/#/R-MMU-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Mus musculus 17504 R-MMU-1482856 https://reactome.org/PathwayBrowser/#/R-MMU-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Mus musculus 17504 R-MMU-1602399 https://reactome.org/PathwayBrowser/#/R-MMU-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Mus musculus 17504 R-MMU-1602417 https://reactome.org/PathwayBrowser/#/R-MMU-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Mus musculus 17504 R-MMU-2029475 https://reactome.org/PathwayBrowser/#/R-MMU-2029475 Production of AA by iPLA2 upon FCGR activation IEA Mus musculus 17504 R-MMU-264679 https://reactome.org/PathwayBrowser/#/R-MMU-264679 Serum albumin binds 2-lysophosphatidylcholine IEA Mus musculus 17504 R-MMU-264695 https://reactome.org/PathwayBrowser/#/R-MMU-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Mus musculus 17504 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 17504 R-MMU-400509 https://reactome.org/PathwayBrowser/#/R-MMU-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Mus musculus 17504 R-MMU-8848484 https://reactome.org/PathwayBrowser/#/R-MMU-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Mus musculus 17504 R-MMU-8849345 https://reactome.org/PathwayBrowser/#/R-MMU-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Mus musculus 17504 R-MMU-8849353 https://reactome.org/PathwayBrowser/#/R-MMU-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Mus musculus 17504 R-PFA-1482547 https://reactome.org/PathwayBrowser/#/R-PFA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Plasmodium falciparum 17504 R-RNO-111883 https://reactome.org/PathwayBrowser/#/R-RNO-111883 Hydrolysis of phosphatidylcholine IEA Rattus norvegicus 17504 R-RNO-1482547 https://reactome.org/PathwayBrowser/#/R-RNO-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Rattus norvegicus 17504 R-RNO-1482685 https://reactome.org/PathwayBrowser/#/R-RNO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 17504 R-RNO-1482696 https://reactome.org/PathwayBrowser/#/R-RNO-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Rattus norvegicus 17504 R-RNO-1482781 https://reactome.org/PathwayBrowser/#/R-RNO-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Rattus norvegicus 17504 R-RNO-1482794 https://reactome.org/PathwayBrowser/#/R-RNO-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Rattus norvegicus 17504 R-RNO-1482816 https://reactome.org/PathwayBrowser/#/R-RNO-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Rattus norvegicus 17504 R-RNO-1482856 https://reactome.org/PathwayBrowser/#/R-RNO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Rattus norvegicus 17504 R-RNO-1602399 https://reactome.org/PathwayBrowser/#/R-RNO-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Rattus norvegicus 17504 R-RNO-1602417 https://reactome.org/PathwayBrowser/#/R-RNO-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Rattus norvegicus 17504 R-RNO-2029475 https://reactome.org/PathwayBrowser/#/R-RNO-2029475 Production of AA by iPLA2 upon FCGR activation IEA Rattus norvegicus 17504 R-RNO-264679 https://reactome.org/PathwayBrowser/#/R-RNO-264679 Serum albumin binds 2-lysophosphatidylcholine IEA Rattus norvegicus 17504 R-RNO-264695 https://reactome.org/PathwayBrowser/#/R-RNO-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Rattus norvegicus 17504 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 17504 R-RNO-400509 https://reactome.org/PathwayBrowser/#/R-RNO-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Rattus norvegicus 17504 R-RNO-8848484 https://reactome.org/PathwayBrowser/#/R-RNO-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Rattus norvegicus 17504 R-RNO-8849345 https://reactome.org/PathwayBrowser/#/R-RNO-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Rattus norvegicus 17504 R-RNO-8849353 https://reactome.org/PathwayBrowser/#/R-RNO-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Rattus norvegicus 17504 R-SCE-111883 https://reactome.org/PathwayBrowser/#/R-SCE-111883 Hydrolysis of phosphatidylcholine IEA Saccharomyces cerevisiae 17504 R-SCE-1482547 https://reactome.org/PathwayBrowser/#/R-SCE-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Saccharomyces cerevisiae 17504 R-SCE-1482685 https://reactome.org/PathwayBrowser/#/R-SCE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 17504 R-SCE-1482696 https://reactome.org/PathwayBrowser/#/R-SCE-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Saccharomyces cerevisiae 17504 R-SCE-1482781 https://reactome.org/PathwayBrowser/#/R-SCE-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 17504 R-SCE-1482794 https://reactome.org/PathwayBrowser/#/R-SCE-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 17504 R-SCE-1482816 https://reactome.org/PathwayBrowser/#/R-SCE-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Saccharomyces cerevisiae 17504 R-SCE-1482856 https://reactome.org/PathwayBrowser/#/R-SCE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Saccharomyces cerevisiae 17504 R-SCE-264695 https://reactome.org/PathwayBrowser/#/R-SCE-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Saccharomyces cerevisiae 17504 R-SCE-8848484 https://reactome.org/PathwayBrowser/#/R-SCE-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Saccharomyces cerevisiae 17504 R-SCE-8849345 https://reactome.org/PathwayBrowser/#/R-SCE-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Saccharomyces cerevisiae 17504 R-SPO-111883 https://reactome.org/PathwayBrowser/#/R-SPO-111883 Hydrolysis of phosphatidylcholine IEA Schizosaccharomyces pombe 17504 R-SPO-1482547 https://reactome.org/PathwayBrowser/#/R-SPO-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Schizosaccharomyces pombe 17504 R-SPO-1482685 https://reactome.org/PathwayBrowser/#/R-SPO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 17504 R-SPO-1482696 https://reactome.org/PathwayBrowser/#/R-SPO-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Schizosaccharomyces pombe 17504 R-SPO-1482816 https://reactome.org/PathwayBrowser/#/R-SPO-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Schizosaccharomyces pombe 17504 R-SPO-1482856 https://reactome.org/PathwayBrowser/#/R-SPO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Schizosaccharomyces pombe 17504 R-SPO-8848484 https://reactome.org/PathwayBrowser/#/R-SPO-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Schizosaccharomyces pombe 17504 R-SSC-111883 https://reactome.org/PathwayBrowser/#/R-SSC-111883 Hydrolysis of phosphatidylcholine IEA Sus scrofa 17504 R-SSC-1482547 https://reactome.org/PathwayBrowser/#/R-SSC-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Sus scrofa 17504 R-SSC-1482685 https://reactome.org/PathwayBrowser/#/R-SSC-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 17504 R-SSC-1482781 https://reactome.org/PathwayBrowser/#/R-SSC-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Sus scrofa 17504 R-SSC-1482794 https://reactome.org/PathwayBrowser/#/R-SSC-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Sus scrofa 17504 R-SSC-1482816 https://reactome.org/PathwayBrowser/#/R-SSC-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Sus scrofa 17504 R-SSC-1482856 https://reactome.org/PathwayBrowser/#/R-SSC-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Sus scrofa 17504 R-SSC-1602399 https://reactome.org/PathwayBrowser/#/R-SSC-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Sus scrofa 17504 R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa 17504 R-SSC-2029475 https://reactome.org/PathwayBrowser/#/R-SSC-2029475 Production of AA by iPLA2 upon FCGR activation IEA Sus scrofa 17504 R-SSC-264679 https://reactome.org/PathwayBrowser/#/R-SSC-264679 Serum albumin binds 2-lysophosphatidylcholine IEA Sus scrofa 17504 R-SSC-264695 https://reactome.org/PathwayBrowser/#/R-SSC-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Sus scrofa 17504 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 17504 R-SSC-400509 https://reactome.org/PathwayBrowser/#/R-SSC-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Sus scrofa 17504 R-SSC-8848484 https://reactome.org/PathwayBrowser/#/R-SSC-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Sus scrofa 17504 R-SSC-8849345 https://reactome.org/PathwayBrowser/#/R-SSC-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Sus scrofa 17504 R-XTR-111883 https://reactome.org/PathwayBrowser/#/R-XTR-111883 Hydrolysis of phosphatidylcholine IEA Xenopus tropicalis 17504 R-XTR-1482547 https://reactome.org/PathwayBrowser/#/R-XTR-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Xenopus tropicalis 17504 R-XTR-1482685 https://reactome.org/PathwayBrowser/#/R-XTR-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 17504 R-XTR-1482781 https://reactome.org/PathwayBrowser/#/R-XTR-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Xenopus tropicalis 17504 R-XTR-1482794 https://reactome.org/PathwayBrowser/#/R-XTR-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Xenopus tropicalis 17504 R-XTR-1482816 https://reactome.org/PathwayBrowser/#/R-XTR-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Xenopus tropicalis 17504 R-XTR-1482856 https://reactome.org/PathwayBrowser/#/R-XTR-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Xenopus tropicalis 17504 R-XTR-1602417 https://reactome.org/PathwayBrowser/#/R-XTR-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Xenopus tropicalis 17504 R-XTR-2029475 https://reactome.org/PathwayBrowser/#/R-XTR-2029475 Production of AA by iPLA2 upon FCGR activation IEA Xenopus tropicalis 17504 R-XTR-264679 https://reactome.org/PathwayBrowser/#/R-XTR-264679 Serum albumin binds 2-lysophosphatidylcholine IEA Xenopus tropicalis 17504 R-XTR-264695 https://reactome.org/PathwayBrowser/#/R-XTR-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Xenopus tropicalis 17504 R-XTR-8848484 https://reactome.org/PathwayBrowser/#/R-XTR-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Xenopus tropicalis 17504 R-XTR-8849345 https://reactome.org/PathwayBrowser/#/R-XTR-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Xenopus tropicalis 17509 R-BTA-1237160 https://reactome.org/PathwayBrowser/#/R-BTA-1237160 MTA is cleaved and phosphorylated IEA Bos taurus 17509 R-BTA-351210 https://reactome.org/PathwayBrowser/#/R-BTA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Bos taurus 17509 R-BTA-351215 https://reactome.org/PathwayBrowser/#/R-BTA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Bos taurus 17509 R-BTA-5358494 https://reactome.org/PathwayBrowser/#/R-BTA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Bos taurus 17509 R-CEL-1237160 https://reactome.org/PathwayBrowser/#/R-CEL-1237160 MTA is cleaved and phosphorylated IEA Caenorhabditis elegans 17509 R-CEL-351215 https://reactome.org/PathwayBrowser/#/R-CEL-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Caenorhabditis elegans 17509 R-CEL-5358494 https://reactome.org/PathwayBrowser/#/R-CEL-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Caenorhabditis elegans 17509 R-CFA-1237160 https://reactome.org/PathwayBrowser/#/R-CFA-1237160 MTA is cleaved and phosphorylated IEA Canis familiaris 17509 R-CFA-351210 https://reactome.org/PathwayBrowser/#/R-CFA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Canis familiaris 17509 R-CFA-351215 https://reactome.org/PathwayBrowser/#/R-CFA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Canis familiaris 17509 R-CFA-5358494 https://reactome.org/PathwayBrowser/#/R-CFA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Canis familiaris 17509 R-DDI-351215 https://reactome.org/PathwayBrowser/#/R-DDI-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Dictyostelium discoideum 17509 R-DDI-5358494 https://reactome.org/PathwayBrowser/#/R-DDI-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Dictyostelium discoideum 17509 R-DME-1237160 https://reactome.org/PathwayBrowser/#/R-DME-1237160 MTA is cleaved and phosphorylated IEA Drosophila melanogaster 17509 R-DME-351210 https://reactome.org/PathwayBrowser/#/R-DME-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Drosophila melanogaster 17509 R-DME-351215 https://reactome.org/PathwayBrowser/#/R-DME-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Drosophila melanogaster 17509 R-DME-5358494 https://reactome.org/PathwayBrowser/#/R-DME-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Drosophila melanogaster 17509 R-DRE-1237160 https://reactome.org/PathwayBrowser/#/R-DRE-1237160 MTA is cleaved and phosphorylated IEA Danio rerio 17509 R-DRE-351210 https://reactome.org/PathwayBrowser/#/R-DRE-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Danio rerio 17509 R-DRE-5358494 https://reactome.org/PathwayBrowser/#/R-DRE-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Danio rerio 17509 R-GGA-1237160 https://reactome.org/PathwayBrowser/#/R-GGA-1237160 MTA is cleaved and phosphorylated IEA Gallus gallus 17509 R-GGA-351210 https://reactome.org/PathwayBrowser/#/R-GGA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Gallus gallus 17509 R-GGA-351215 https://reactome.org/PathwayBrowser/#/R-GGA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Gallus gallus 17509 R-GGA-5358494 https://reactome.org/PathwayBrowser/#/R-GGA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Gallus gallus 17509 R-HSA-1237160 https://reactome.org/PathwayBrowser/#/R-HSA-1237160 MTA is cleaved and phosphorylated TAS Homo sapiens 17509 R-HSA-351210 https://reactome.org/PathwayBrowser/#/R-HSA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine TAS Homo sapiens 17509 R-HSA-351215 https://reactome.org/PathwayBrowser/#/R-HSA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine TAS Homo sapiens 17509 R-HSA-5358494 https://reactome.org/PathwayBrowser/#/R-HSA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 TAS Homo sapiens 17509 R-HSA-6782893 https://reactome.org/PathwayBrowser/#/R-HSA-6782893 TRMT12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 17509 R-HSA-8868783 https://reactome.org/PathwayBrowser/#/R-HSA-8868783 TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248 TAS Homo sapiens 17509 R-MMU-1237160 https://reactome.org/PathwayBrowser/#/R-MMU-1237160 MTA is cleaved and phosphorylated IEA Mus musculus 17509 R-MMU-351210 https://reactome.org/PathwayBrowser/#/R-MMU-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Mus musculus 17509 R-MMU-351215 https://reactome.org/PathwayBrowser/#/R-MMU-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Mus musculus 17509 R-MMU-5358494 https://reactome.org/PathwayBrowser/#/R-MMU-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Mus musculus 17509 R-PFA-351215 https://reactome.org/PathwayBrowser/#/R-PFA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Plasmodium falciparum 17509 R-PFA-5358494 https://reactome.org/PathwayBrowser/#/R-PFA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Plasmodium falciparum 17509 R-RNO-1237160 https://reactome.org/PathwayBrowser/#/R-RNO-1237160 MTA is cleaved and phosphorylated IEA Rattus norvegicus 17509 R-RNO-351210 https://reactome.org/PathwayBrowser/#/R-RNO-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Rattus norvegicus 17509 R-RNO-351215 https://reactome.org/PathwayBrowser/#/R-RNO-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Rattus norvegicus 17509 R-SCE-1237160 https://reactome.org/PathwayBrowser/#/R-SCE-1237160 MTA is cleaved and phosphorylated IEA Saccharomyces cerevisiae 17509 R-SCE-351215 https://reactome.org/PathwayBrowser/#/R-SCE-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Saccharomyces cerevisiae 17509 R-SCE-5358494 https://reactome.org/PathwayBrowser/#/R-SCE-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Saccharomyces cerevisiae 17509 R-SCE-6783410 https://reactome.org/PathwayBrowser/#/R-SCE-6783410 TRM12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 17509 R-SPO-1237160 https://reactome.org/PathwayBrowser/#/R-SPO-1237160 MTA is cleaved and phosphorylated IEA Schizosaccharomyces pombe 17509 R-SPO-351215 https://reactome.org/PathwayBrowser/#/R-SPO-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Schizosaccharomyces pombe 17509 R-SPO-5358494 https://reactome.org/PathwayBrowser/#/R-SPO-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Schizosaccharomyces pombe 17509 R-SSC-1237160 https://reactome.org/PathwayBrowser/#/R-SSC-1237160 MTA is cleaved and phosphorylated IEA Sus scrofa 17509 R-SSC-351210 https://reactome.org/PathwayBrowser/#/R-SSC-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Sus scrofa 17509 R-SSC-351215 https://reactome.org/PathwayBrowser/#/R-SSC-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Sus scrofa 17509 R-SSC-5358494 https://reactome.org/PathwayBrowser/#/R-SSC-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Sus scrofa 17509 R-XTR-1237160 https://reactome.org/PathwayBrowser/#/R-XTR-1237160 MTA is cleaved and phosphorylated IEA Xenopus tropicalis 17509 R-XTR-351210 https://reactome.org/PathwayBrowser/#/R-XTR-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Xenopus tropicalis 17509 R-XTR-351215 https://reactome.org/PathwayBrowser/#/R-XTR-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Xenopus tropicalis 17509 R-XTR-5358494 https://reactome.org/PathwayBrowser/#/R-XTR-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Xenopus tropicalis 17526 R-BTA-1675780 https://reactome.org/PathwayBrowser/#/R-BTA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Bos taurus 17526 R-BTA-1675813 https://reactome.org/PathwayBrowser/#/R-BTA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Bos taurus 17526 R-BTA-1675824 https://reactome.org/PathwayBrowser/#/R-BTA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Bos taurus 17526 R-BTA-1675883 https://reactome.org/PathwayBrowser/#/R-BTA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Bos taurus 17526 R-BTA-1675928 https://reactome.org/PathwayBrowser/#/R-BTA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Bos taurus 17526 R-BTA-1675974 https://reactome.org/PathwayBrowser/#/R-BTA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Bos taurus 17526 R-BTA-1675988 https://reactome.org/PathwayBrowser/#/R-BTA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Bos taurus 17526 R-BTA-1676082 https://reactome.org/PathwayBrowser/#/R-BTA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Bos taurus 17526 R-BTA-1676109 https://reactome.org/PathwayBrowser/#/R-BTA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Bos taurus 17526 R-BTA-1676124 https://reactome.org/PathwayBrowser/#/R-BTA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Bos taurus 17526 R-BTA-1676133 https://reactome.org/PathwayBrowser/#/R-BTA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Bos taurus 17526 R-BTA-1676149 https://reactome.org/PathwayBrowser/#/R-BTA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Bos taurus 17526 R-BTA-1676177 https://reactome.org/PathwayBrowser/#/R-BTA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Bos taurus 17526 R-BTA-1676185 https://reactome.org/PathwayBrowser/#/R-BTA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Bos taurus 17526 R-BTA-1676204 https://reactome.org/PathwayBrowser/#/R-BTA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Bos taurus 17526 R-BTA-1676206 https://reactome.org/PathwayBrowser/#/R-BTA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Bos taurus 17526 R-BTA-3772436 https://reactome.org/PathwayBrowser/#/R-BTA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Bos taurus 17526 R-BTA-449058 https://reactome.org/PathwayBrowser/#/R-BTA-449058 Interleukin-1 family are secreted IEA Bos taurus 17526 R-BTA-5620975 https://reactome.org/PathwayBrowser/#/R-BTA-5620975 MLKL binds PIPs IEA Bos taurus 17526 R-BTA-6805981 https://reactome.org/PathwayBrowser/#/R-BTA-6805981 HMGB1 release from cells IEA Bos taurus 17526 R-BTA-8867876 https://reactome.org/PathwayBrowser/#/R-BTA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Bos taurus 17526 R-BTA-8868066 https://reactome.org/PathwayBrowser/#/R-BTA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Bos taurus 17526 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 17526 R-BTA-8868402 https://reactome.org/PathwayBrowser/#/R-BTA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Bos taurus 17526 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 17526 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 17526 R-BTA-8868659 https://reactome.org/PathwayBrowser/#/R-BTA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Bos taurus 17526 R-BTA-8868660 https://reactome.org/PathwayBrowser/#/R-BTA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Bos taurus 17526 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 17526 R-BTA-8870499 https://reactome.org/PathwayBrowser/#/R-BTA-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Bos taurus 17526 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 17526 R-BTA-8871194 https://reactome.org/PathwayBrowser/#/R-BTA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Bos taurus 17526 R-BTA-9647619 https://reactome.org/PathwayBrowser/#/R-BTA-9647619 GSDMD forms ring‐shaped oligomers IEA Bos taurus 17526 R-BTA-9647631 https://reactome.org/PathwayBrowser/#/R-BTA-9647631 GSDMD (1-275) binds PIPs IEA Bos taurus 17526 R-BTA-9647645 https://reactome.org/PathwayBrowser/#/R-BTA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Bos taurus 17526 R-BTA-9647660 https://reactome.org/PathwayBrowser/#/R-BTA-9647660 GSDME (1-270) binds PIPs IEA Bos taurus 17526 R-BTA-9710254 https://reactome.org/PathwayBrowser/#/R-BTA-9710254 GSDME oligomerizes IEA Bos taurus 17526 R-BTA-9845055 https://reactome.org/PathwayBrowser/#/R-BTA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Bos taurus 17526 R-CEL-1675780 https://reactome.org/PathwayBrowser/#/R-CEL-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Caenorhabditis elegans 17526 R-CEL-1675813 https://reactome.org/PathwayBrowser/#/R-CEL-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Caenorhabditis elegans 17526 R-CEL-1675824 https://reactome.org/PathwayBrowser/#/R-CEL-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Caenorhabditis elegans 17526 R-CEL-1675883 https://reactome.org/PathwayBrowser/#/R-CEL-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Caenorhabditis elegans 17526 R-CEL-1675974 https://reactome.org/PathwayBrowser/#/R-CEL-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Caenorhabditis elegans 17526 R-CEL-1675988 https://reactome.org/PathwayBrowser/#/R-CEL-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Caenorhabditis elegans 17526 R-CEL-1676082 https://reactome.org/PathwayBrowser/#/R-CEL-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Caenorhabditis elegans 17526 R-CEL-1676109 https://reactome.org/PathwayBrowser/#/R-CEL-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Caenorhabditis elegans 17526 R-CEL-1676124 https://reactome.org/PathwayBrowser/#/R-CEL-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Caenorhabditis elegans 17526 R-CEL-1676133 https://reactome.org/PathwayBrowser/#/R-CEL-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Caenorhabditis elegans 17526 R-CEL-1676149 https://reactome.org/PathwayBrowser/#/R-CEL-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Caenorhabditis elegans 17526 R-CEL-1676177 https://reactome.org/PathwayBrowser/#/R-CEL-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Caenorhabditis elegans 17526 R-CEL-1676185 https://reactome.org/PathwayBrowser/#/R-CEL-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Caenorhabditis elegans 17526 R-CEL-3772436 https://reactome.org/PathwayBrowser/#/R-CEL-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Caenorhabditis elegans 17526 R-CEL-8867876 https://reactome.org/PathwayBrowser/#/R-CEL-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Caenorhabditis elegans 17526 R-CEL-8868066 https://reactome.org/PathwayBrowser/#/R-CEL-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Caenorhabditis elegans 17526 R-CEL-8868072 https://reactome.org/PathwayBrowser/#/R-CEL-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Caenorhabditis elegans 17526 R-CEL-8868402 https://reactome.org/PathwayBrowser/#/R-CEL-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Caenorhabditis elegans 17526 R-CEL-8868648 https://reactome.org/PathwayBrowser/#/R-CEL-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Caenorhabditis elegans 17526 R-CEL-8868658 https://reactome.org/PathwayBrowser/#/R-CEL-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Caenorhabditis elegans 17526 R-CEL-8868659 https://reactome.org/PathwayBrowser/#/R-CEL-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Caenorhabditis elegans 17526 R-CEL-8868660 https://reactome.org/PathwayBrowser/#/R-CEL-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Caenorhabditis elegans 17526 R-CEL-8868661 https://reactome.org/PathwayBrowser/#/R-CEL-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Caenorhabditis elegans 17526 R-CEL-8871194 https://reactome.org/PathwayBrowser/#/R-CEL-8871194 RAB5 and GAPVD1 bind AP-2 IEA Caenorhabditis elegans 17526 R-CFA-1675780 https://reactome.org/PathwayBrowser/#/R-CFA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Canis familiaris 17526 R-CFA-1675813 https://reactome.org/PathwayBrowser/#/R-CFA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Canis familiaris 17526 R-CFA-1675824 https://reactome.org/PathwayBrowser/#/R-CFA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Canis familiaris 17526 R-CFA-1675883 https://reactome.org/PathwayBrowser/#/R-CFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Canis familiaris 17526 R-CFA-1675928 https://reactome.org/PathwayBrowser/#/R-CFA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Canis familiaris 17526 R-CFA-1675974 https://reactome.org/PathwayBrowser/#/R-CFA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Canis familiaris 17526 R-CFA-1675988 https://reactome.org/PathwayBrowser/#/R-CFA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Canis familiaris 17526 R-CFA-1676082 https://reactome.org/PathwayBrowser/#/R-CFA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Canis familiaris 17526 R-CFA-1676109 https://reactome.org/PathwayBrowser/#/R-CFA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Canis familiaris 17526 R-CFA-1676124 https://reactome.org/PathwayBrowser/#/R-CFA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Canis familiaris 17526 R-CFA-1676133 https://reactome.org/PathwayBrowser/#/R-CFA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Canis familiaris 17526 R-CFA-1676149 https://reactome.org/PathwayBrowser/#/R-CFA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Canis familiaris 17526 R-CFA-1676177 https://reactome.org/PathwayBrowser/#/R-CFA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Canis familiaris 17526 R-CFA-1676185 https://reactome.org/PathwayBrowser/#/R-CFA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Canis familiaris 17526 R-CFA-1676204 https://reactome.org/PathwayBrowser/#/R-CFA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Canis familiaris 17526 R-CFA-1676206 https://reactome.org/PathwayBrowser/#/R-CFA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Canis familiaris 17526 R-CFA-3772436 https://reactome.org/PathwayBrowser/#/R-CFA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Canis familiaris 17526 R-CFA-449058 https://reactome.org/PathwayBrowser/#/R-CFA-449058 Interleukin-1 family are secreted IEA Canis familiaris 17526 R-CFA-6805981 https://reactome.org/PathwayBrowser/#/R-CFA-6805981 HMGB1 release from cells IEA Canis familiaris 17526 R-CFA-8867876 https://reactome.org/PathwayBrowser/#/R-CFA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Canis familiaris 17526 R-CFA-8868066 https://reactome.org/PathwayBrowser/#/R-CFA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Canis familiaris 17526 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 17526 R-CFA-8868402 https://reactome.org/PathwayBrowser/#/R-CFA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Canis familiaris 17526 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 17526 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 17526 R-CFA-8868659 https://reactome.org/PathwayBrowser/#/R-CFA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Canis familiaris 17526 R-CFA-8868660 https://reactome.org/PathwayBrowser/#/R-CFA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Canis familiaris 17526 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 17526 R-CFA-8870499 https://reactome.org/PathwayBrowser/#/R-CFA-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Canis familiaris 17526 R-CFA-8871193 https://reactome.org/PathwayBrowser/#/R-CFA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Canis familiaris 17526 R-CFA-8871194 https://reactome.org/PathwayBrowser/#/R-CFA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Canis familiaris 17526 R-CFA-9647619 https://reactome.org/PathwayBrowser/#/R-CFA-9647619 GSDMD forms ring‐shaped oligomers IEA Canis familiaris 17526 R-CFA-9647631 https://reactome.org/PathwayBrowser/#/R-CFA-9647631 GSDMD (1-275) binds PIPs IEA Canis familiaris 17526 R-CFA-9647645 https://reactome.org/PathwayBrowser/#/R-CFA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Canis familiaris 17526 R-CFA-9647660 https://reactome.org/PathwayBrowser/#/R-CFA-9647660 GSDME (1-270) binds PIPs IEA Canis familiaris 17526 R-CFA-9710254 https://reactome.org/PathwayBrowser/#/R-CFA-9710254 GSDME oligomerizes IEA Canis familiaris 17526 R-CFA-9845055 https://reactome.org/PathwayBrowser/#/R-CFA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Canis familiaris 17526 R-DDI-1675813 https://reactome.org/PathwayBrowser/#/R-DDI-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Dictyostelium discoideum 17526 R-DDI-1675824 https://reactome.org/PathwayBrowser/#/R-DDI-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Dictyostelium discoideum 17526 R-DDI-1675883 https://reactome.org/PathwayBrowser/#/R-DDI-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Dictyostelium discoideum 17526 R-DDI-1675928 https://reactome.org/PathwayBrowser/#/R-DDI-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Dictyostelium discoideum 17526 R-DDI-1675988 https://reactome.org/PathwayBrowser/#/R-DDI-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Dictyostelium discoideum 17526 R-DDI-1676082 https://reactome.org/PathwayBrowser/#/R-DDI-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Dictyostelium discoideum 17526 R-DDI-1676109 https://reactome.org/PathwayBrowser/#/R-DDI-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Dictyostelium discoideum 17526 R-DDI-1676124 https://reactome.org/PathwayBrowser/#/R-DDI-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Dictyostelium discoideum 17526 R-DDI-1676133 https://reactome.org/PathwayBrowser/#/R-DDI-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Dictyostelium discoideum 17526 R-DDI-1676149 https://reactome.org/PathwayBrowser/#/R-DDI-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Dictyostelium discoideum 17526 R-DDI-1676177 https://reactome.org/PathwayBrowser/#/R-DDI-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Dictyostelium discoideum 17526 R-DDI-1676185 https://reactome.org/PathwayBrowser/#/R-DDI-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Dictyostelium discoideum 17526 R-DDI-1676204 https://reactome.org/PathwayBrowser/#/R-DDI-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Dictyostelium discoideum 17526 R-DDI-1676206 https://reactome.org/PathwayBrowser/#/R-DDI-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Dictyostelium discoideum 17526 R-DDI-8867876 https://reactome.org/PathwayBrowser/#/R-DDI-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Dictyostelium discoideum 17526 R-DDI-8868066 https://reactome.org/PathwayBrowser/#/R-DDI-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Dictyostelium discoideum 17526 R-DDI-8868072 https://reactome.org/PathwayBrowser/#/R-DDI-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Dictyostelium discoideum 17526 R-DDI-8868402 https://reactome.org/PathwayBrowser/#/R-DDI-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Dictyostelium discoideum 17526 R-DME-1675780 https://reactome.org/PathwayBrowser/#/R-DME-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Drosophila melanogaster 17526 R-DME-1675813 https://reactome.org/PathwayBrowser/#/R-DME-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Drosophila melanogaster 17526 R-DME-1675824 https://reactome.org/PathwayBrowser/#/R-DME-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Drosophila melanogaster 17526 R-DME-1675883 https://reactome.org/PathwayBrowser/#/R-DME-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Drosophila melanogaster 17526 R-DME-1675928 https://reactome.org/PathwayBrowser/#/R-DME-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Drosophila melanogaster 17526 R-DME-1675974 https://reactome.org/PathwayBrowser/#/R-DME-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Drosophila melanogaster 17526 R-DME-1675988 https://reactome.org/PathwayBrowser/#/R-DME-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Drosophila melanogaster 17526 R-DME-1676082 https://reactome.org/PathwayBrowser/#/R-DME-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Drosophila melanogaster 17526 R-DME-1676109 https://reactome.org/PathwayBrowser/#/R-DME-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Drosophila melanogaster 17526 R-DME-1676124 https://reactome.org/PathwayBrowser/#/R-DME-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Drosophila melanogaster 17526 R-DME-1676133 https://reactome.org/PathwayBrowser/#/R-DME-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Drosophila melanogaster 17526 R-DME-1676149 https://reactome.org/PathwayBrowser/#/R-DME-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Drosophila melanogaster 17526 R-DME-1676177 https://reactome.org/PathwayBrowser/#/R-DME-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Drosophila melanogaster 17526 R-DME-1676185 https://reactome.org/PathwayBrowser/#/R-DME-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Drosophila melanogaster 17526 R-DME-1676206 https://reactome.org/PathwayBrowser/#/R-DME-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Drosophila melanogaster 17526 R-DME-3772436 https://reactome.org/PathwayBrowser/#/R-DME-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Drosophila melanogaster 17526 R-DME-8867876 https://reactome.org/PathwayBrowser/#/R-DME-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Drosophila melanogaster 17526 R-DME-8868066 https://reactome.org/PathwayBrowser/#/R-DME-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Drosophila melanogaster 17526 R-DME-8868072 https://reactome.org/PathwayBrowser/#/R-DME-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Drosophila melanogaster 17526 R-DME-8868402 https://reactome.org/PathwayBrowser/#/R-DME-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Drosophila melanogaster 17526 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster 17526 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster 17526 R-DME-8868660 https://reactome.org/PathwayBrowser/#/R-DME-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Drosophila melanogaster 17526 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster 17526 R-DME-8870499 https://reactome.org/PathwayBrowser/#/R-DME-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Drosophila melanogaster 17526 R-DME-8871194 https://reactome.org/PathwayBrowser/#/R-DME-8871194 RAB5 and GAPVD1 bind AP-2 IEA Drosophila melanogaster 17526 R-DRE-1675780 https://reactome.org/PathwayBrowser/#/R-DRE-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Danio rerio 17526 R-DRE-1675813 https://reactome.org/PathwayBrowser/#/R-DRE-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Danio rerio 17526 R-DRE-1675883 https://reactome.org/PathwayBrowser/#/R-DRE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Danio rerio 17526 R-DRE-1675974 https://reactome.org/PathwayBrowser/#/R-DRE-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Danio rerio 17526 R-DRE-1676082 https://reactome.org/PathwayBrowser/#/R-DRE-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Danio rerio 17526 R-DRE-1676109 https://reactome.org/PathwayBrowser/#/R-DRE-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Danio rerio 17526 R-DRE-1676124 https://reactome.org/PathwayBrowser/#/R-DRE-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Danio rerio 17526 R-DRE-1676133 https://reactome.org/PathwayBrowser/#/R-DRE-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Danio rerio 17526 R-DRE-1676149 https://reactome.org/PathwayBrowser/#/R-DRE-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Danio rerio 17526 R-DRE-1676185 https://reactome.org/PathwayBrowser/#/R-DRE-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Danio rerio 17526 R-DRE-1676204 https://reactome.org/PathwayBrowser/#/R-DRE-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Danio rerio 17526 R-DRE-6805981 https://reactome.org/PathwayBrowser/#/R-DRE-6805981 HMGB1 release from cells IEA Danio rerio 17526 R-DRE-8870499 https://reactome.org/PathwayBrowser/#/R-DRE-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Danio rerio 17526 R-DRE-9647660 https://reactome.org/PathwayBrowser/#/R-DRE-9647660 GSDME (1-270) binds PIPs IEA Danio rerio 17526 R-DRE-9710254 https://reactome.org/PathwayBrowser/#/R-DRE-9710254 GSDME oligomerizes IEA Danio rerio 17526 R-DRE-9845055 https://reactome.org/PathwayBrowser/#/R-DRE-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Danio rerio 17526 R-GGA-1675780 https://reactome.org/PathwayBrowser/#/R-GGA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Gallus gallus 17526 R-GGA-1675813 https://reactome.org/PathwayBrowser/#/R-GGA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Gallus gallus 17526 R-GGA-1675824 https://reactome.org/PathwayBrowser/#/R-GGA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Gallus gallus 17526 R-GGA-1675883 https://reactome.org/PathwayBrowser/#/R-GGA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Gallus gallus 17526 R-GGA-1675928 https://reactome.org/PathwayBrowser/#/R-GGA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Gallus gallus 17526 R-GGA-1675974 https://reactome.org/PathwayBrowser/#/R-GGA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Gallus gallus 17526 R-GGA-1675988 https://reactome.org/PathwayBrowser/#/R-GGA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Gallus gallus 17526 R-GGA-1676082 https://reactome.org/PathwayBrowser/#/R-GGA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Gallus gallus 17526 R-GGA-1676109 https://reactome.org/PathwayBrowser/#/R-GGA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Gallus gallus 17526 R-GGA-1676124 https://reactome.org/PathwayBrowser/#/R-GGA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Gallus gallus 17526 R-GGA-1676133 https://reactome.org/PathwayBrowser/#/R-GGA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Gallus gallus 17526 R-GGA-1676149 https://reactome.org/PathwayBrowser/#/R-GGA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Gallus gallus 17526 R-GGA-1676177 https://reactome.org/PathwayBrowser/#/R-GGA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Gallus gallus 17526 R-GGA-1676185 https://reactome.org/PathwayBrowser/#/R-GGA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Gallus gallus 17526 R-GGA-1676204 https://reactome.org/PathwayBrowser/#/R-GGA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Gallus gallus 17526 R-GGA-1676206 https://reactome.org/PathwayBrowser/#/R-GGA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Gallus gallus 17526 R-GGA-3772436 https://reactome.org/PathwayBrowser/#/R-GGA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Gallus gallus 17526 R-GGA-449058 https://reactome.org/PathwayBrowser/#/R-GGA-449058 Interleukin-1 family are secreted IEA Gallus gallus 17526 R-GGA-6805981 https://reactome.org/PathwayBrowser/#/R-GGA-6805981 HMGB1 release from cells IEA Gallus gallus 17526 R-GGA-8867876 https://reactome.org/PathwayBrowser/#/R-GGA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Gallus gallus 17526 R-GGA-8868066 https://reactome.org/PathwayBrowser/#/R-GGA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Gallus gallus 17526 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus 17526 R-GGA-8868402 https://reactome.org/PathwayBrowser/#/R-GGA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Gallus gallus 17526 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus 17526 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus 17526 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus 17526 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus 17526 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus 17526 R-GGA-8870499 https://reactome.org/PathwayBrowser/#/R-GGA-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Gallus gallus 17526 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus 17526 R-GGA-9647619 https://reactome.org/PathwayBrowser/#/R-GGA-9647619 GSDMD forms ring‐shaped oligomers IEA Gallus gallus 17526 R-GGA-9647631 https://reactome.org/PathwayBrowser/#/R-GGA-9647631 GSDMD (1-275) binds PIPs IEA Gallus gallus 17526 R-GGA-9647645 https://reactome.org/PathwayBrowser/#/R-GGA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Gallus gallus 17526 R-GGA-9647660 https://reactome.org/PathwayBrowser/#/R-GGA-9647660 GSDME (1-270) binds PIPs IEA Gallus gallus 17526 R-GGA-9710254 https://reactome.org/PathwayBrowser/#/R-GGA-9710254 GSDME oligomerizes IEA Gallus gallus 17526 R-GGA-9845055 https://reactome.org/PathwayBrowser/#/R-GGA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Gallus gallus 17526 R-HSA-1675780 https://reactome.org/PathwayBrowser/#/R-HSA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane TAS Homo sapiens 17526 R-HSA-1675813 https://reactome.org/PathwayBrowser/#/R-HSA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane TAS Homo sapiens 17526 R-HSA-1675815 https://reactome.org/PathwayBrowser/#/R-HSA-1675815 PI4P transports from the Golgi membrane to the plasma membrane TAS Homo sapiens 17526 R-HSA-1675824 https://reactome.org/PathwayBrowser/#/R-HSA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane TAS Homo sapiens 17526 R-HSA-1675883 https://reactome.org/PathwayBrowser/#/R-HSA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane TAS Homo sapiens 17526 R-HSA-1675928 https://reactome.org/PathwayBrowser/#/R-HSA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane TAS Homo sapiens 17526 R-HSA-1675974 https://reactome.org/PathwayBrowser/#/R-HSA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane TAS Homo sapiens 17526 R-HSA-1675988 https://reactome.org/PathwayBrowser/#/R-HSA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane TAS Homo sapiens 17526 R-HSA-1676082 https://reactome.org/PathwayBrowser/#/R-HSA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane TAS Homo sapiens 17526 R-HSA-1676109 https://reactome.org/PathwayBrowser/#/R-HSA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane TAS Homo sapiens 17526 R-HSA-1676124 https://reactome.org/PathwayBrowser/#/R-HSA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane TAS Homo sapiens 17526 R-HSA-1676133 https://reactome.org/PathwayBrowser/#/R-HSA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane TAS Homo sapiens 17526 R-HSA-1676149 https://reactome.org/PathwayBrowser/#/R-HSA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane TAS Homo sapiens 17526 R-HSA-1676177 https://reactome.org/PathwayBrowser/#/R-HSA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane TAS Homo sapiens 17526 R-HSA-1676185 https://reactome.org/PathwayBrowser/#/R-HSA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane TAS Homo sapiens 17526 R-HSA-1676204 https://reactome.org/PathwayBrowser/#/R-HSA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane TAS Homo sapiens 17526 R-HSA-1676206 https://reactome.org/PathwayBrowser/#/R-HSA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane TAS Homo sapiens 17526 R-HSA-3772436 https://reactome.org/PathwayBrowser/#/R-HSA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 TAS Homo sapiens 17526 R-HSA-449058 https://reactome.org/PathwayBrowser/#/R-HSA-449058 Interleukin-1 family are secreted TAS Homo sapiens 17526 R-HSA-5620975 https://reactome.org/PathwayBrowser/#/R-HSA-5620975 MLKL binds PIPs TAS Homo sapiens 17526 R-HSA-6805981 https://reactome.org/PathwayBrowser/#/R-HSA-6805981 HMGB1 release from cells TAS Homo sapiens 17526 R-HSA-8867876 https://reactome.org/PathwayBrowser/#/R-HSA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane TAS Homo sapiens 17526 R-HSA-8868066 https://reactome.org/PathwayBrowser/#/R-HSA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 TAS Homo sapiens 17526 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 17526 R-HSA-8868402 https://reactome.org/PathwayBrowser/#/R-HSA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane TAS Homo sapiens 17526 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 17526 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 17526 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 17526 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 17526 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 17526 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 17526 R-HSA-8870499 https://reactome.org/PathwayBrowser/#/R-HSA-8870499 PLEKHA3,8 bind PI4P, ARF1 TAS Homo sapiens 17526 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 17526 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 17526 R-HSA-9647619 https://reactome.org/PathwayBrowser/#/R-HSA-9647619 GSDMD forms ring‐shaped oligomers TAS Homo sapiens 17526 R-HSA-9647631 https://reactome.org/PathwayBrowser/#/R-HSA-9647631 GSDMD (1-275) binds PIPs TAS Homo sapiens 17526 R-HSA-9647645 https://reactome.org/PathwayBrowser/#/R-HSA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures TAS Homo sapiens 17526 R-HSA-9647660 https://reactome.org/PathwayBrowser/#/R-HSA-9647660 GSDME (1-270) binds PIPs TAS Homo sapiens 17526 R-HSA-9710254 https://reactome.org/PathwayBrowser/#/R-HSA-9710254 GSDME oligomerizes TAS Homo sapiens 17526 R-HSA-9710468 https://reactome.org/PathwayBrowser/#/R-HSA-9710468 GSDME variant does not bind PIPs TAS Homo sapiens 17526 R-HSA-9845055 https://reactome.org/PathwayBrowser/#/R-HSA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane TAS Homo sapiens 17526 R-MMU-1675780 https://reactome.org/PathwayBrowser/#/R-MMU-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Mus musculus 17526 R-MMU-1675813 https://reactome.org/PathwayBrowser/#/R-MMU-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Mus musculus 17526 R-MMU-1675824 https://reactome.org/PathwayBrowser/#/R-MMU-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Mus musculus 17526 R-MMU-1675883 https://reactome.org/PathwayBrowser/#/R-MMU-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Mus musculus 17526 R-MMU-1675928 https://reactome.org/PathwayBrowser/#/R-MMU-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Mus musculus 17526 R-MMU-1675974 https://reactome.org/PathwayBrowser/#/R-MMU-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Mus musculus 17526 R-MMU-1675988 https://reactome.org/PathwayBrowser/#/R-MMU-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Mus musculus 17526 R-MMU-1676082 https://reactome.org/PathwayBrowser/#/R-MMU-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Mus musculus 17526 R-MMU-1676109 https://reactome.org/PathwayBrowser/#/R-MMU-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Mus musculus 17526 R-MMU-1676124 https://reactome.org/PathwayBrowser/#/R-MMU-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Mus musculus 17526 R-MMU-1676133 https://reactome.org/PathwayBrowser/#/R-MMU-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Mus musculus 17526 R-MMU-1676149 https://reactome.org/PathwayBrowser/#/R-MMU-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Mus musculus 17526 R-MMU-1676177 https://reactome.org/PathwayBrowser/#/R-MMU-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Mus musculus 17526 R-MMU-1676185 https://reactome.org/PathwayBrowser/#/R-MMU-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Mus musculus 17526 R-MMU-1676204 https://reactome.org/PathwayBrowser/#/R-MMU-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Mus musculus 17526 R-MMU-1676206 https://reactome.org/PathwayBrowser/#/R-MMU-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Mus musculus 17526 R-MMU-3772436 https://reactome.org/PathwayBrowser/#/R-MMU-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Mus musculus 17526 R-MMU-449058 https://reactome.org/PathwayBrowser/#/R-MMU-449058 Interleukin-1 family are secreted IEA Mus musculus 17526 R-MMU-5620975 https://reactome.org/PathwayBrowser/#/R-MMU-5620975 MLKL binds PIPs IEA Mus musculus 17526 R-MMU-6805981 https://reactome.org/PathwayBrowser/#/R-MMU-6805981 HMGB1 release from cells IEA Mus musculus 17526 R-MMU-8867876 https://reactome.org/PathwayBrowser/#/R-MMU-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Mus musculus 17526 R-MMU-8868066 https://reactome.org/PathwayBrowser/#/R-MMU-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Mus musculus 17526 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 17526 R-MMU-8868402 https://reactome.org/PathwayBrowser/#/R-MMU-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Mus musculus 17526 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 17526 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 17526 R-MMU-8868659 https://reactome.org/PathwayBrowser/#/R-MMU-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Mus musculus 17526 R-MMU-8868660 https://reactome.org/PathwayBrowser/#/R-MMU-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Mus musculus 17526 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 17526 R-MMU-8870499 https://reactome.org/PathwayBrowser/#/R-MMU-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Mus musculus 17526 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 17526 R-MMU-8871194 https://reactome.org/PathwayBrowser/#/R-MMU-8871194 RAB5 and GAPVD1 bind AP-2 IEA Mus musculus 17526 R-MMU-9647619 https://reactome.org/PathwayBrowser/#/R-MMU-9647619 GSDMD forms ring‐shaped oligomers IEA Mus musculus 17526 R-MMU-9647631 https://reactome.org/PathwayBrowser/#/R-MMU-9647631 GSDMD (1-275) binds PIPs IEA Mus musculus 17526 R-MMU-9647645 https://reactome.org/PathwayBrowser/#/R-MMU-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Mus musculus 17526 R-MMU-9647660 https://reactome.org/PathwayBrowser/#/R-MMU-9647660 GSDME (1-270) binds PIPs IEA Mus musculus 17526 R-MMU-9710254 https://reactome.org/PathwayBrowser/#/R-MMU-9710254 GSDME oligomerizes IEA Mus musculus 17526 R-MMU-9845055 https://reactome.org/PathwayBrowser/#/R-MMU-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Mus musculus 17526 R-PFA-1675824 https://reactome.org/PathwayBrowser/#/R-PFA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Plasmodium falciparum 17526 R-PFA-1675883 https://reactome.org/PathwayBrowser/#/R-PFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Plasmodium falciparum 17526 R-PFA-1675988 https://reactome.org/PathwayBrowser/#/R-PFA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Plasmodium falciparum 17526 R-PFA-1676082 https://reactome.org/PathwayBrowser/#/R-PFA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Plasmodium falciparum 17526 R-PFA-1676124 https://reactome.org/PathwayBrowser/#/R-PFA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Plasmodium falciparum 17526 R-PFA-1676133 https://reactome.org/PathwayBrowser/#/R-PFA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Plasmodium falciparum 17526 R-PFA-1676177 https://reactome.org/PathwayBrowser/#/R-PFA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Plasmodium falciparum 17526 R-PFA-8868066 https://reactome.org/PathwayBrowser/#/R-PFA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Plasmodium falciparum 17526 R-PFA-8868402 https://reactome.org/PathwayBrowser/#/R-PFA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Plasmodium falciparum 17526 R-PFA-8870499 https://reactome.org/PathwayBrowser/#/R-PFA-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Plasmodium falciparum 17526 R-PFA-9845055 https://reactome.org/PathwayBrowser/#/R-PFA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Plasmodium falciparum 17526 R-RNO-1675780 https://reactome.org/PathwayBrowser/#/R-RNO-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Rattus norvegicus 17526 R-RNO-1675813 https://reactome.org/PathwayBrowser/#/R-RNO-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Rattus norvegicus 17526 R-RNO-1675824 https://reactome.org/PathwayBrowser/#/R-RNO-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Rattus norvegicus 17526 R-RNO-1675883 https://reactome.org/PathwayBrowser/#/R-RNO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Rattus norvegicus 17526 R-RNO-1675928 https://reactome.org/PathwayBrowser/#/R-RNO-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Rattus norvegicus 17526 R-RNO-1675974 https://reactome.org/PathwayBrowser/#/R-RNO-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Rattus norvegicus 17526 R-RNO-1675988 https://reactome.org/PathwayBrowser/#/R-RNO-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Rattus norvegicus 17526 R-RNO-1676082 https://reactome.org/PathwayBrowser/#/R-RNO-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Rattus norvegicus 17526 R-RNO-1676109 https://reactome.org/PathwayBrowser/#/R-RNO-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Rattus norvegicus 17526 R-RNO-1676124 https://reactome.org/PathwayBrowser/#/R-RNO-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Rattus norvegicus 17526 R-RNO-1676133 https://reactome.org/PathwayBrowser/#/R-RNO-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Rattus norvegicus 17526 R-RNO-1676149 https://reactome.org/PathwayBrowser/#/R-RNO-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Rattus norvegicus 17526 R-RNO-1676177 https://reactome.org/PathwayBrowser/#/R-RNO-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Rattus norvegicus 17526 R-RNO-1676185 https://reactome.org/PathwayBrowser/#/R-RNO-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Rattus norvegicus 17526 R-RNO-1676204 https://reactome.org/PathwayBrowser/#/R-RNO-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Rattus norvegicus 17526 R-RNO-1676206 https://reactome.org/PathwayBrowser/#/R-RNO-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Rattus norvegicus 17526 R-RNO-3772436 https://reactome.org/PathwayBrowser/#/R-RNO-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Rattus norvegicus 17526 R-RNO-449058 https://reactome.org/PathwayBrowser/#/R-RNO-449058 Interleukin-1 family are secreted IEA Rattus norvegicus 17526 R-RNO-5620975 https://reactome.org/PathwayBrowser/#/R-RNO-5620975 MLKL binds PIPs IEA Rattus norvegicus 17526 R-RNO-6805981 https://reactome.org/PathwayBrowser/#/R-RNO-6805981 HMGB1 release from cells IEA Rattus norvegicus 17526 R-RNO-8867876 https://reactome.org/PathwayBrowser/#/R-RNO-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Rattus norvegicus 17526 R-RNO-8868066 https://reactome.org/PathwayBrowser/#/R-RNO-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Rattus norvegicus 17526 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 17526 R-RNO-8868402 https://reactome.org/PathwayBrowser/#/R-RNO-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Rattus norvegicus 17526 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 17526 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 17526 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus 17526 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus 17526 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 17526 R-RNO-8870499 https://reactome.org/PathwayBrowser/#/R-RNO-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Rattus norvegicus 17526 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 17526 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus 17526 R-RNO-9647619 https://reactome.org/PathwayBrowser/#/R-RNO-9647619 GSDMD forms ring‐shaped oligomers IEA Rattus norvegicus 17526 R-RNO-9647631 https://reactome.org/PathwayBrowser/#/R-RNO-9647631 GSDMD (1-275) binds PIPs IEA Rattus norvegicus 17526 R-RNO-9647645 https://reactome.org/PathwayBrowser/#/R-RNO-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Rattus norvegicus 17526 R-RNO-9647660 https://reactome.org/PathwayBrowser/#/R-RNO-9647660 GSDME (1-270) binds PIPs IEA Rattus norvegicus 17526 R-RNO-9710254 https://reactome.org/PathwayBrowser/#/R-RNO-9710254 GSDME oligomerizes IEA Rattus norvegicus 17526 R-RNO-9845055 https://reactome.org/PathwayBrowser/#/R-RNO-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Rattus norvegicus 17526 R-SCE-1675780 https://reactome.org/PathwayBrowser/#/R-SCE-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Saccharomyces cerevisiae 17526 R-SCE-1675813 https://reactome.org/PathwayBrowser/#/R-SCE-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Saccharomyces cerevisiae 17526 R-SCE-1675883 https://reactome.org/PathwayBrowser/#/R-SCE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Saccharomyces cerevisiae 17526 R-SCE-1675974 https://reactome.org/PathwayBrowser/#/R-SCE-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Saccharomyces cerevisiae 17526 R-SCE-1675988 https://reactome.org/PathwayBrowser/#/R-SCE-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Saccharomyces cerevisiae 17526 R-SCE-1676082 https://reactome.org/PathwayBrowser/#/R-SCE-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Saccharomyces cerevisiae 17526 R-SCE-1676124 https://reactome.org/PathwayBrowser/#/R-SCE-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Saccharomyces cerevisiae 17526 R-SCE-1676133 https://reactome.org/PathwayBrowser/#/R-SCE-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Saccharomyces cerevisiae 17526 R-SCE-1676149 https://reactome.org/PathwayBrowser/#/R-SCE-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Saccharomyces cerevisiae 17526 R-SCE-1676177 https://reactome.org/PathwayBrowser/#/R-SCE-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Saccharomyces cerevisiae 17526 R-SCE-1676185 https://reactome.org/PathwayBrowser/#/R-SCE-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Saccharomyces cerevisiae 17526 R-SCE-1676204 https://reactome.org/PathwayBrowser/#/R-SCE-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Saccharomyces cerevisiae 17526 R-SCE-8867876 https://reactome.org/PathwayBrowser/#/R-SCE-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Saccharomyces cerevisiae 17526 R-SCE-8868066 https://reactome.org/PathwayBrowser/#/R-SCE-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Saccharomyces cerevisiae 17526 R-SCE-8868402 https://reactome.org/PathwayBrowser/#/R-SCE-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Saccharomyces cerevisiae 17526 R-SCE-8870499 https://reactome.org/PathwayBrowser/#/R-SCE-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Saccharomyces cerevisiae 17526 R-SPO-1675780 https://reactome.org/PathwayBrowser/#/R-SPO-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1675813 https://reactome.org/PathwayBrowser/#/R-SPO-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1675824 https://reactome.org/PathwayBrowser/#/R-SPO-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1675883 https://reactome.org/PathwayBrowser/#/R-SPO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1675974 https://reactome.org/PathwayBrowser/#/R-SPO-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1675988 https://reactome.org/PathwayBrowser/#/R-SPO-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1676082 https://reactome.org/PathwayBrowser/#/R-SPO-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1676124 https://reactome.org/PathwayBrowser/#/R-SPO-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1676133 https://reactome.org/PathwayBrowser/#/R-SPO-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1676149 https://reactome.org/PathwayBrowser/#/R-SPO-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1676177 https://reactome.org/PathwayBrowser/#/R-SPO-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1676185 https://reactome.org/PathwayBrowser/#/R-SPO-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Schizosaccharomyces pombe 17526 R-SPO-1676204 https://reactome.org/PathwayBrowser/#/R-SPO-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Schizosaccharomyces pombe 17526 R-SPO-8867876 https://reactome.org/PathwayBrowser/#/R-SPO-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Schizosaccharomyces pombe 17526 R-SPO-8868066 https://reactome.org/PathwayBrowser/#/R-SPO-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Schizosaccharomyces pombe 17526 R-SPO-8868402 https://reactome.org/PathwayBrowser/#/R-SPO-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Schizosaccharomyces pombe 17526 R-SPO-8868660 https://reactome.org/PathwayBrowser/#/R-SPO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Schizosaccharomyces pombe 17526 R-SSC-1675780 https://reactome.org/PathwayBrowser/#/R-SSC-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Sus scrofa 17526 R-SSC-1675813 https://reactome.org/PathwayBrowser/#/R-SSC-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Sus scrofa 17526 R-SSC-1675824 https://reactome.org/PathwayBrowser/#/R-SSC-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Sus scrofa 17526 R-SSC-1675883 https://reactome.org/PathwayBrowser/#/R-SSC-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Sus scrofa 17526 R-SSC-1675928 https://reactome.org/PathwayBrowser/#/R-SSC-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Sus scrofa 17526 R-SSC-1675974 https://reactome.org/PathwayBrowser/#/R-SSC-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Sus scrofa 17526 R-SSC-1675988 https://reactome.org/PathwayBrowser/#/R-SSC-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Sus scrofa 17526 R-SSC-1676082 https://reactome.org/PathwayBrowser/#/R-SSC-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Sus scrofa 17526 R-SSC-1676109 https://reactome.org/PathwayBrowser/#/R-SSC-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Sus scrofa 17526 R-SSC-1676124 https://reactome.org/PathwayBrowser/#/R-SSC-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Sus scrofa 17526 R-SSC-1676133 https://reactome.org/PathwayBrowser/#/R-SSC-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Sus scrofa 17526 R-SSC-1676149 https://reactome.org/PathwayBrowser/#/R-SSC-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Sus scrofa 17526 R-SSC-1676177 https://reactome.org/PathwayBrowser/#/R-SSC-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Sus scrofa 17526 R-SSC-1676185 https://reactome.org/PathwayBrowser/#/R-SSC-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Sus scrofa 17526 R-SSC-1676204 https://reactome.org/PathwayBrowser/#/R-SSC-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Sus scrofa 17526 R-SSC-1676206 https://reactome.org/PathwayBrowser/#/R-SSC-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Sus scrofa 17526 R-SSC-3772436 https://reactome.org/PathwayBrowser/#/R-SSC-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Sus scrofa 17526 R-SSC-449058 https://reactome.org/PathwayBrowser/#/R-SSC-449058 Interleukin-1 family are secreted IEA Sus scrofa 17526 R-SSC-5620975 https://reactome.org/PathwayBrowser/#/R-SSC-5620975 MLKL binds PIPs IEA Sus scrofa 17526 R-SSC-8867876 https://reactome.org/PathwayBrowser/#/R-SSC-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Sus scrofa 17526 R-SSC-8868066 https://reactome.org/PathwayBrowser/#/R-SSC-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Sus scrofa 17526 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 17526 R-SSC-8868402 https://reactome.org/PathwayBrowser/#/R-SSC-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Sus scrofa 17526 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 17526 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 17526 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa 17526 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa 17526 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 17526 R-SSC-8870499 https://reactome.org/PathwayBrowser/#/R-SSC-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Sus scrofa 17526 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 17526 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa 17526 R-SSC-9647619 https://reactome.org/PathwayBrowser/#/R-SSC-9647619 GSDMD forms ring‐shaped oligomers IEA Sus scrofa 17526 R-SSC-9647631 https://reactome.org/PathwayBrowser/#/R-SSC-9647631 GSDMD (1-275) binds PIPs IEA Sus scrofa 17526 R-SSC-9647645 https://reactome.org/PathwayBrowser/#/R-SSC-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Sus scrofa 17526 R-SSC-9647660 https://reactome.org/PathwayBrowser/#/R-SSC-9647660 GSDME (1-270) binds PIPs IEA Sus scrofa 17526 R-SSC-9710254 https://reactome.org/PathwayBrowser/#/R-SSC-9710254 GSDME oligomerizes IEA Sus scrofa 17526 R-SSC-9845055 https://reactome.org/PathwayBrowser/#/R-SSC-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Sus scrofa 17526 R-XTR-1675780 https://reactome.org/PathwayBrowser/#/R-XTR-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Xenopus tropicalis 17526 R-XTR-1675813 https://reactome.org/PathwayBrowser/#/R-XTR-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Xenopus tropicalis 17526 R-XTR-1675824 https://reactome.org/PathwayBrowser/#/R-XTR-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Xenopus tropicalis 17526 R-XTR-1675883 https://reactome.org/PathwayBrowser/#/R-XTR-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Xenopus tropicalis 17526 R-XTR-1675928 https://reactome.org/PathwayBrowser/#/R-XTR-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Xenopus tropicalis 17526 R-XTR-1675974 https://reactome.org/PathwayBrowser/#/R-XTR-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Xenopus tropicalis 17526 R-XTR-1675988 https://reactome.org/PathwayBrowser/#/R-XTR-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Xenopus tropicalis 17526 R-XTR-1676082 https://reactome.org/PathwayBrowser/#/R-XTR-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Xenopus tropicalis 17526 R-XTR-1676109 https://reactome.org/PathwayBrowser/#/R-XTR-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Xenopus tropicalis 17526 R-XTR-1676149 https://reactome.org/PathwayBrowser/#/R-XTR-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Xenopus tropicalis 17526 R-XTR-1676177 https://reactome.org/PathwayBrowser/#/R-XTR-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Xenopus tropicalis 17526 R-XTR-1676185 https://reactome.org/PathwayBrowser/#/R-XTR-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Xenopus tropicalis 17526 R-XTR-1676204 https://reactome.org/PathwayBrowser/#/R-XTR-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Xenopus tropicalis 17526 R-XTR-1676206 https://reactome.org/PathwayBrowser/#/R-XTR-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Xenopus tropicalis 17526 R-XTR-6805981 https://reactome.org/PathwayBrowser/#/R-XTR-6805981 HMGB1 release from cells IEA Xenopus tropicalis 17526 R-XTR-8867876 https://reactome.org/PathwayBrowser/#/R-XTR-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Xenopus tropicalis 17526 R-XTR-8868066 https://reactome.org/PathwayBrowser/#/R-XTR-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Xenopus tropicalis 17526 R-XTR-8870499 https://reactome.org/PathwayBrowser/#/R-XTR-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Xenopus tropicalis 17526 R-XTR-9647660 https://reactome.org/PathwayBrowser/#/R-XTR-9647660 GSDME (1-270) binds PIPs IEA Xenopus tropicalis 17526 R-XTR-9710254 https://reactome.org/PathwayBrowser/#/R-XTR-9710254 GSDME oligomerizes IEA Xenopus tropicalis 17526 R-XTR-9845055 https://reactome.org/PathwayBrowser/#/R-XTR-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Xenopus tropicalis 17533 R-BTA-70542 https://reactome.org/PathwayBrowser/#/R-BTA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Bos taurus 17533 R-BTA-70555 https://reactome.org/PathwayBrowser/#/R-BTA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Bos taurus 17533 R-CFA-70542 https://reactome.org/PathwayBrowser/#/R-CFA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Canis familiaris 17533 R-CFA-70555 https://reactome.org/PathwayBrowser/#/R-CFA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Canis familiaris 17533 R-DDI-70542 https://reactome.org/PathwayBrowser/#/R-DDI-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Dictyostelium discoideum 17533 R-DRE-70542 https://reactome.org/PathwayBrowser/#/R-DRE-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Danio rerio 17533 R-GGA-70555 https://reactome.org/PathwayBrowser/#/R-GGA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Gallus gallus 17533 R-HSA-70542 https://reactome.org/PathwayBrowser/#/R-HSA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA TAS Homo sapiens 17533 R-HSA-70555 https://reactome.org/PathwayBrowser/#/R-HSA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] TAS Homo sapiens 17533 R-MMU-70542 https://reactome.org/PathwayBrowser/#/R-MMU-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Mus musculus 17533 R-MMU-70555 https://reactome.org/PathwayBrowser/#/R-MMU-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Mus musculus 17533 R-RNO-70542 https://reactome.org/PathwayBrowser/#/R-RNO-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Rattus norvegicus 17533 R-RNO-70555 https://reactome.org/PathwayBrowser/#/R-RNO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Rattus norvegicus 17533 R-SCE-70542 https://reactome.org/PathwayBrowser/#/R-SCE-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Saccharomyces cerevisiae 17533 R-SCE-70555 https://reactome.org/PathwayBrowser/#/R-SCE-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Saccharomyces cerevisiae 17533 R-SPO-70542 https://reactome.org/PathwayBrowser/#/R-SPO-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Schizosaccharomyces pombe 17533 R-SPO-70555 https://reactome.org/PathwayBrowser/#/R-SPO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Schizosaccharomyces pombe 17533 R-SSC-70542 https://reactome.org/PathwayBrowser/#/R-SSC-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Sus scrofa 17533 R-SSC-70555 https://reactome.org/PathwayBrowser/#/R-SSC-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Sus scrofa 17533 R-XTR-70542 https://reactome.org/PathwayBrowser/#/R-XTR-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Xenopus tropicalis 17533 R-XTR-70555 https://reactome.org/PathwayBrowser/#/R-XTR-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Xenopus tropicalis 17544 R-BTA-1237038 https://reactome.org/PathwayBrowser/#/R-BTA-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Bos taurus 17544 R-BTA-1237045 https://reactome.org/PathwayBrowser/#/R-BTA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Bos taurus 17544 R-BTA-1237047 https://reactome.org/PathwayBrowser/#/R-BTA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Bos taurus 17544 R-BTA-1237059 https://reactome.org/PathwayBrowser/#/R-BTA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Bos taurus 17544 R-BTA-1237081 https://reactome.org/PathwayBrowser/#/R-BTA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Bos taurus 17544 R-BTA-1247665 https://reactome.org/PathwayBrowser/#/R-BTA-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Bos taurus 17544 R-BTA-1475017 https://reactome.org/PathwayBrowser/#/R-BTA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Bos taurus 17544 R-BTA-1475022 https://reactome.org/PathwayBrowser/#/R-BTA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Bos taurus 17544 R-BTA-1475025 https://reactome.org/PathwayBrowser/#/R-BTA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Bos taurus 17544 R-BTA-1475026 https://reactome.org/PathwayBrowser/#/R-BTA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Bos taurus 17544 R-BTA-1475028 https://reactome.org/PathwayBrowser/#/R-BTA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Bos taurus 17544 R-BTA-1475032 https://reactome.org/PathwayBrowser/#/R-BTA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Bos taurus 17544 R-BTA-1475435 https://reactome.org/PathwayBrowser/#/R-BTA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Bos taurus 17544 R-BTA-1475436 https://reactome.org/PathwayBrowser/#/R-BTA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Bos taurus 17544 R-BTA-200555 https://reactome.org/PathwayBrowser/#/R-BTA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Bos taurus 17544 R-BTA-2752067 https://reactome.org/PathwayBrowser/#/R-BTA-2752067 BESTs transport cytosolic HCO3- to extracellular region IEA Bos taurus 17544 R-BTA-383190 https://reactome.org/PathwayBrowser/#/R-BTA-383190 HCO3- transport through ion channel IEA Bos taurus 17544 R-BTA-425482 https://reactome.org/PathwayBrowser/#/R-BTA-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Bos taurus 17544 R-BTA-425483 https://reactome.org/PathwayBrowser/#/R-BTA-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Bos taurus 17544 R-BTA-425577 https://reactome.org/PathwayBrowser/#/R-BTA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Bos taurus 17544 R-BTA-427666 https://reactome.org/PathwayBrowser/#/R-BTA-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Bos taurus 17544 R-BTA-508308 https://reactome.org/PathwayBrowser/#/R-BTA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Bos taurus 17544 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 17544 R-BTA-70555 https://reactome.org/PathwayBrowser/#/R-BTA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Bos taurus 17544 R-BTA-70773 https://reactome.org/PathwayBrowser/#/R-BTA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Bos taurus 17544 R-BTA-73577 https://reactome.org/PathwayBrowser/#/R-BTA-73577 CAD hexamer transforms L-Gln to CAP IEA Bos taurus 17544 R-BTA-75851 https://reactome.org/PathwayBrowser/#/R-BTA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 17544 R-BTA-8876889 https://reactome.org/PathwayBrowser/#/R-BTA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 17544 R-BTA-8878664 https://reactome.org/PathwayBrowser/#/R-BTA-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Bos taurus 17544 R-CEL-1237038 https://reactome.org/PathwayBrowser/#/R-CEL-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Caenorhabditis elegans 17544 R-CEL-1237045 https://reactome.org/PathwayBrowser/#/R-CEL-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Caenorhabditis elegans 17544 R-CEL-1237047 https://reactome.org/PathwayBrowser/#/R-CEL-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Caenorhabditis elegans 17544 R-CEL-1237059 https://reactome.org/PathwayBrowser/#/R-CEL-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Caenorhabditis elegans 17544 R-CEL-1237081 https://reactome.org/PathwayBrowser/#/R-CEL-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Caenorhabditis elegans 17544 R-CEL-1247665 https://reactome.org/PathwayBrowser/#/R-CEL-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Caenorhabditis elegans 17544 R-CEL-1475017 https://reactome.org/PathwayBrowser/#/R-CEL-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Caenorhabditis elegans 17544 R-CEL-1475022 https://reactome.org/PathwayBrowser/#/R-CEL-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Caenorhabditis elegans 17544 R-CEL-1475025 https://reactome.org/PathwayBrowser/#/R-CEL-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Caenorhabditis elegans 17544 R-CEL-1475026 https://reactome.org/PathwayBrowser/#/R-CEL-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Caenorhabditis elegans 17544 R-CEL-1475028 https://reactome.org/PathwayBrowser/#/R-CEL-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Caenorhabditis elegans 17544 R-CEL-1475032 https://reactome.org/PathwayBrowser/#/R-CEL-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Caenorhabditis elegans 17544 R-CEL-1475435 https://reactome.org/PathwayBrowser/#/R-CEL-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Caenorhabditis elegans 17544 R-CEL-1475436 https://reactome.org/PathwayBrowser/#/R-CEL-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Caenorhabditis elegans 17544 R-CEL-200555 https://reactome.org/PathwayBrowser/#/R-CEL-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Caenorhabditis elegans 17544 R-CEL-383190 https://reactome.org/PathwayBrowser/#/R-CEL-383190 HCO3- transport through ion channel IEA Caenorhabditis elegans 17544 R-CEL-425482 https://reactome.org/PathwayBrowser/#/R-CEL-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Caenorhabditis elegans 17544 R-CEL-425483 https://reactome.org/PathwayBrowser/#/R-CEL-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Caenorhabditis elegans 17544 R-CEL-425577 https://reactome.org/PathwayBrowser/#/R-CEL-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Caenorhabditis elegans 17544 R-CEL-427666 https://reactome.org/PathwayBrowser/#/R-CEL-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Caenorhabditis elegans 17544 R-CEL-508308 https://reactome.org/PathwayBrowser/#/R-CEL-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Caenorhabditis elegans 17544 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 17544 R-CEL-70773 https://reactome.org/PathwayBrowser/#/R-CEL-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Caenorhabditis elegans 17544 R-CEL-73577 https://reactome.org/PathwayBrowser/#/R-CEL-73577 CAD hexamer transforms L-Gln to CAP IEA Caenorhabditis elegans 17544 R-CEL-75851 https://reactome.org/PathwayBrowser/#/R-CEL-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 17544 R-CEL-8876889 https://reactome.org/PathwayBrowser/#/R-CEL-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 17544 R-CEL-8878664 https://reactome.org/PathwayBrowser/#/R-CEL-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Caenorhabditis elegans 17544 R-CFA-1237038 https://reactome.org/PathwayBrowser/#/R-CFA-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Canis familiaris 17544 R-CFA-1237045 https://reactome.org/PathwayBrowser/#/R-CFA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Canis familiaris 17544 R-CFA-1237047 https://reactome.org/PathwayBrowser/#/R-CFA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Canis familiaris 17544 R-CFA-1237059 https://reactome.org/PathwayBrowser/#/R-CFA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Canis familiaris 17544 R-CFA-1237081 https://reactome.org/PathwayBrowser/#/R-CFA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Canis familiaris 17544 R-CFA-1247665 https://reactome.org/PathwayBrowser/#/R-CFA-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Canis familiaris 17544 R-CFA-1475017 https://reactome.org/PathwayBrowser/#/R-CFA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Canis familiaris 17544 R-CFA-1475022 https://reactome.org/PathwayBrowser/#/R-CFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Canis familiaris 17544 R-CFA-1475025 https://reactome.org/PathwayBrowser/#/R-CFA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Canis familiaris 17544 R-CFA-1475026 https://reactome.org/PathwayBrowser/#/R-CFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Canis familiaris 17544 R-CFA-1475028 https://reactome.org/PathwayBrowser/#/R-CFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Canis familiaris 17544 R-CFA-1475032 https://reactome.org/PathwayBrowser/#/R-CFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Canis familiaris 17544 R-CFA-1475435 https://reactome.org/PathwayBrowser/#/R-CFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Canis familiaris 17544 R-CFA-1475436 https://reactome.org/PathwayBrowser/#/R-CFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Canis familiaris 17544 R-CFA-200555 https://reactome.org/PathwayBrowser/#/R-CFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Canis familiaris 17544 R-CFA-2752067 https://reactome.org/PathwayBrowser/#/R-CFA-2752067 BESTs transport cytosolic HCO3- to extracellular region IEA Canis familiaris 17544 R-CFA-383190 https://reactome.org/PathwayBrowser/#/R-CFA-383190 HCO3- transport through ion channel IEA Canis familiaris 17544 R-CFA-425482 https://reactome.org/PathwayBrowser/#/R-CFA-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Canis familiaris 17544 R-CFA-425483 https://reactome.org/PathwayBrowser/#/R-CFA-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Canis familiaris 17544 R-CFA-425577 https://reactome.org/PathwayBrowser/#/R-CFA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Canis familiaris 17544 R-CFA-427666 https://reactome.org/PathwayBrowser/#/R-CFA-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Canis familiaris 17544 R-CFA-508308 https://reactome.org/PathwayBrowser/#/R-CFA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Canis familiaris 17544 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 17544 R-CFA-70555 https://reactome.org/PathwayBrowser/#/R-CFA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Canis familiaris 17544 R-CFA-70773 https://reactome.org/PathwayBrowser/#/R-CFA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Canis familiaris 17544 R-CFA-73577 https://reactome.org/PathwayBrowser/#/R-CFA-73577 CAD hexamer transforms L-Gln to CAP IEA Canis familiaris 17544 R-CFA-75851 https://reactome.org/PathwayBrowser/#/R-CFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 17544 R-CFA-8876889 https://reactome.org/PathwayBrowser/#/R-CFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 17544 R-CFA-8878664 https://reactome.org/PathwayBrowser/#/R-CFA-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Canis familiaris 17544 R-DDI-200555 https://reactome.org/PathwayBrowser/#/R-DDI-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Dictyostelium discoideum 17544 R-DDI-383190 https://reactome.org/PathwayBrowser/#/R-DDI-383190 HCO3- transport through ion channel IEA Dictyostelium discoideum 17544 R-DDI-427666 https://reactome.org/PathwayBrowser/#/R-DDI-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Dictyostelium discoideum 17544 R-DDI-508308 https://reactome.org/PathwayBrowser/#/R-DDI-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Dictyostelium discoideum 17544 R-DDI-70773 https://reactome.org/PathwayBrowser/#/R-DDI-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Dictyostelium discoideum 17544 R-DDI-73577 https://reactome.org/PathwayBrowser/#/R-DDI-73577 CAD hexamer transforms L-Gln to CAP IEA Dictyostelium discoideum 17544 R-DDI-75851 https://reactome.org/PathwayBrowser/#/R-DDI-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 17544 R-DDI-8876889 https://reactome.org/PathwayBrowser/#/R-DDI-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 17544 R-DME-1237038 https://reactome.org/PathwayBrowser/#/R-DME-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Drosophila melanogaster 17544 R-DME-1237045 https://reactome.org/PathwayBrowser/#/R-DME-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Drosophila melanogaster 17544 R-DME-1237047 https://reactome.org/PathwayBrowser/#/R-DME-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Drosophila melanogaster 17544 R-DME-1237059 https://reactome.org/PathwayBrowser/#/R-DME-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Drosophila melanogaster 17544 R-DME-1237081 https://reactome.org/PathwayBrowser/#/R-DME-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Drosophila melanogaster 17544 R-DME-1247665 https://reactome.org/PathwayBrowser/#/R-DME-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Drosophila melanogaster 17544 R-DME-1475017 https://reactome.org/PathwayBrowser/#/R-DME-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Drosophila melanogaster 17544 R-DME-1475022 https://reactome.org/PathwayBrowser/#/R-DME-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Drosophila melanogaster 17544 R-DME-1475025 https://reactome.org/PathwayBrowser/#/R-DME-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Drosophila melanogaster 17544 R-DME-1475026 https://reactome.org/PathwayBrowser/#/R-DME-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Drosophila melanogaster 17544 R-DME-1475028 https://reactome.org/PathwayBrowser/#/R-DME-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Drosophila melanogaster 17544 R-DME-1475032 https://reactome.org/PathwayBrowser/#/R-DME-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Drosophila melanogaster 17544 R-DME-1475435 https://reactome.org/PathwayBrowser/#/R-DME-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Drosophila melanogaster 17544 R-DME-1475436 https://reactome.org/PathwayBrowser/#/R-DME-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Drosophila melanogaster 17544 R-DME-200555 https://reactome.org/PathwayBrowser/#/R-DME-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Drosophila melanogaster 17544 R-DME-2752067 https://reactome.org/PathwayBrowser/#/R-DME-2752067 BESTs transport cytosolic HCO3- to extracellular region IEA Drosophila melanogaster 17544 R-DME-383190 https://reactome.org/PathwayBrowser/#/R-DME-383190 HCO3- transport through ion channel IEA Drosophila melanogaster 17544 R-DME-425482 https://reactome.org/PathwayBrowser/#/R-DME-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Drosophila melanogaster 17544 R-DME-425483 https://reactome.org/PathwayBrowser/#/R-DME-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Drosophila melanogaster 17544 R-DME-425577 https://reactome.org/PathwayBrowser/#/R-DME-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Drosophila melanogaster 17544 R-DME-427666 https://reactome.org/PathwayBrowser/#/R-DME-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Drosophila melanogaster 17544 R-DME-508308 https://reactome.org/PathwayBrowser/#/R-DME-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Drosophila melanogaster 17544 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 17544 R-DME-70773 https://reactome.org/PathwayBrowser/#/R-DME-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Drosophila melanogaster 17544 R-DME-73577 https://reactome.org/PathwayBrowser/#/R-DME-73577 CAD hexamer transforms L-Gln to CAP IEA Drosophila melanogaster 17544 R-DME-75851 https://reactome.org/PathwayBrowser/#/R-DME-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 17544 R-DME-8876889 https://reactome.org/PathwayBrowser/#/R-DME-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 17544 R-DME-8878664 https://reactome.org/PathwayBrowser/#/R-DME-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Drosophila melanogaster 17544 R-DRE-1237038 https://reactome.org/PathwayBrowser/#/R-DRE-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Danio rerio 17544 R-DRE-1237047 https://reactome.org/PathwayBrowser/#/R-DRE-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Danio rerio 17544 R-DRE-1237059 https://reactome.org/PathwayBrowser/#/R-DRE-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Danio rerio 17544 R-DRE-1247665 https://reactome.org/PathwayBrowser/#/R-DRE-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Danio rerio 17544 R-DRE-1475017 https://reactome.org/PathwayBrowser/#/R-DRE-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Danio rerio 17544 R-DRE-1475022 https://reactome.org/PathwayBrowser/#/R-DRE-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Danio rerio 17544 R-DRE-1475025 https://reactome.org/PathwayBrowser/#/R-DRE-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Danio rerio 17544 R-DRE-1475026 https://reactome.org/PathwayBrowser/#/R-DRE-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Danio rerio 17544 R-DRE-1475028 https://reactome.org/PathwayBrowser/#/R-DRE-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Danio rerio 17544 R-DRE-1475032 https://reactome.org/PathwayBrowser/#/R-DRE-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Danio rerio 17544 R-DRE-1475435 https://reactome.org/PathwayBrowser/#/R-DRE-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Danio rerio 17544 R-DRE-1475436 https://reactome.org/PathwayBrowser/#/R-DRE-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Danio rerio 17544 R-DRE-383190 https://reactome.org/PathwayBrowser/#/R-DRE-383190 HCO3- transport through ion channel IEA Danio rerio 17544 R-DRE-425482 https://reactome.org/PathwayBrowser/#/R-DRE-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Danio rerio 17544 R-DRE-427666 https://reactome.org/PathwayBrowser/#/R-DRE-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Danio rerio 17544 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 17544 R-GGA-1237038 https://reactome.org/PathwayBrowser/#/R-GGA-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Gallus gallus 17544 R-GGA-1237045 https://reactome.org/PathwayBrowser/#/R-GGA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Gallus gallus 17544 R-GGA-1237047 https://reactome.org/PathwayBrowser/#/R-GGA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Gallus gallus 17544 R-GGA-1237059 https://reactome.org/PathwayBrowser/#/R-GGA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Gallus gallus 17544 R-GGA-1237081 https://reactome.org/PathwayBrowser/#/R-GGA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Gallus gallus 17544 R-GGA-1247665 https://reactome.org/PathwayBrowser/#/R-GGA-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Gallus gallus 17544 R-GGA-1475017 https://reactome.org/PathwayBrowser/#/R-GGA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Gallus gallus 17544 R-GGA-1475022 https://reactome.org/PathwayBrowser/#/R-GGA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Gallus gallus 17544 R-GGA-1475025 https://reactome.org/PathwayBrowser/#/R-GGA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Gallus gallus 17544 R-GGA-1475026 https://reactome.org/PathwayBrowser/#/R-GGA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Gallus gallus 17544 R-GGA-1475028 https://reactome.org/PathwayBrowser/#/R-GGA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Gallus gallus 17544 R-GGA-1475032 https://reactome.org/PathwayBrowser/#/R-GGA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Gallus gallus 17544 R-GGA-1475435 https://reactome.org/PathwayBrowser/#/R-GGA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Gallus gallus 17544 R-GGA-1475436 https://reactome.org/PathwayBrowser/#/R-GGA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Gallus gallus 17544 R-GGA-200555 https://reactome.org/PathwayBrowser/#/R-GGA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Gallus gallus 17544 R-GGA-2752067 https://reactome.org/PathwayBrowser/#/R-GGA-2752067 BESTs transport cytosolic HCO3- to extracellular region IEA Gallus gallus 17544 R-GGA-383190 https://reactome.org/PathwayBrowser/#/R-GGA-383190 HCO3- transport through ion channel IEA Gallus gallus 17544 R-GGA-419440 https://reactome.org/PathwayBrowser/#/R-GGA-419440 L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate IEA Gallus gallus 17544 R-GGA-425482 https://reactome.org/PathwayBrowser/#/R-GGA-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Gallus gallus 17544 R-GGA-425483 https://reactome.org/PathwayBrowser/#/R-GGA-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Gallus gallus 17544 R-GGA-425577 https://reactome.org/PathwayBrowser/#/R-GGA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Gallus gallus 17544 R-GGA-427666 https://reactome.org/PathwayBrowser/#/R-GGA-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Gallus gallus 17544 R-GGA-508308 https://reactome.org/PathwayBrowser/#/R-GGA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Gallus gallus 17544 R-GGA-70555 https://reactome.org/PathwayBrowser/#/R-GGA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Gallus gallus 17544 R-GGA-70773 https://reactome.org/PathwayBrowser/#/R-GGA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Gallus gallus 17544 R-GGA-75851 https://reactome.org/PathwayBrowser/#/R-GGA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Gallus gallus 17544 R-GGA-8878664 https://reactome.org/PathwayBrowser/#/R-GGA-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Gallus gallus 17544 R-HSA-1237038 https://reactome.org/PathwayBrowser/#/R-HSA-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- TAS Homo sapiens 17544 R-HSA-1237045 https://reactome.org/PathwayBrowser/#/R-HSA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton TAS Homo sapiens 17544 R-HSA-1237047 https://reactome.org/PathwayBrowser/#/R-HSA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- TAS Homo sapiens 17544 R-HSA-1237059 https://reactome.org/PathwayBrowser/#/R-HSA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 TAS Homo sapiens 17544 R-HSA-1237081 https://reactome.org/PathwayBrowser/#/R-HSA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide TAS Homo sapiens 17544 R-HSA-1247665 https://reactome.org/PathwayBrowser/#/R-HSA-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- TAS Homo sapiens 17544 R-HSA-1475017 https://reactome.org/PathwayBrowser/#/R-HSA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) TAS Homo sapiens 17544 R-HSA-1475022 https://reactome.org/PathwayBrowser/#/R-HSA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) TAS Homo sapiens 17544 R-HSA-1475025 https://reactome.org/PathwayBrowser/#/R-HSA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) TAS Homo sapiens 17544 R-HSA-1475026 https://reactome.org/PathwayBrowser/#/R-HSA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) TAS Homo sapiens 17544 R-HSA-1475028 https://reactome.org/PathwayBrowser/#/R-HSA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) TAS Homo sapiens 17544 R-HSA-1475032 https://reactome.org/PathwayBrowser/#/R-HSA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) TAS Homo sapiens 17544 R-HSA-1475435 https://reactome.org/PathwayBrowser/#/R-HSA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- TAS Homo sapiens 17544 R-HSA-1475436 https://reactome.org/PathwayBrowser/#/R-HSA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 TAS Homo sapiens 17544 R-HSA-200555 https://reactome.org/PathwayBrowser/#/R-HSA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate TAS Homo sapiens 17544 R-HSA-2752067 https://reactome.org/PathwayBrowser/#/R-HSA-2752067 BESTs transport cytosolic HCO3- to extracellular region TAS Homo sapiens 17544 R-HSA-383190 https://reactome.org/PathwayBrowser/#/R-HSA-383190 HCO3- transport through ion channel TAS Homo sapiens 17544 R-HSA-425482 https://reactome.org/PathwayBrowser/#/R-HSA-425482 SLC4A1,2,3 exchanges HCO3- for Cl- TAS Homo sapiens 17544 R-HSA-425483 https://reactome.org/PathwayBrowser/#/R-HSA-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- TAS Homo sapiens 17544 R-HSA-425577 https://reactome.org/PathwayBrowser/#/R-HSA-425577 Na+-driven Cl-/HCO3- exchanger transport TAS Homo sapiens 17544 R-HSA-427666 https://reactome.org/PathwayBrowser/#/R-HSA-427666 SLC26A3,6 exchange Cl- for HCO3- TAS Homo sapiens 17544 R-HSA-508308 https://reactome.org/PathwayBrowser/#/R-HSA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] TAS Homo sapiens 17544 R-HSA-5627737 https://reactome.org/PathwayBrowser/#/R-HSA-5627737 SLC26A3 does not exchange Cl- for HCO3- TAS Homo sapiens 17544 R-HSA-5656219 https://reactome.org/PathwayBrowser/#/R-HSA-5656219 Defective SLC4A4 does not cotransport Na+ with 3HCO3- TAS Homo sapiens 17544 R-HSA-5656248 https://reactome.org/PathwayBrowser/#/R-HSA-5656248 Defective SLC4A1 does not exchange Cl- for HCO3- (in erythrocytes) TAS Homo sapiens 17544 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 17544 R-HSA-70555 https://reactome.org/PathwayBrowser/#/R-HSA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] TAS Homo sapiens 17544 R-HSA-70773 https://reactome.org/PathwayBrowser/#/R-HSA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] TAS Homo sapiens 17544 R-HSA-73577 https://reactome.org/PathwayBrowser/#/R-HSA-73577 CAD hexamer transforms L-Gln to CAP TAS Homo sapiens 17544 R-HSA-75851 https://reactome.org/PathwayBrowser/#/R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 17544 R-HSA-8876889 https://reactome.org/PathwayBrowser/#/R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 17544 R-HSA-8878664 https://reactome.org/PathwayBrowser/#/R-HSA-8878664 SLC4A4 cotransports Na+ with 3HCO3- TAS Homo sapiens 17544 R-HSA-9663354 https://reactome.org/PathwayBrowser/#/R-HSA-9663354 SLC26A5 (prestin) changes conformation in response to depolarization IEA Homo sapiens 17544 R-MMU-1237038 https://reactome.org/PathwayBrowser/#/R-MMU-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Mus musculus 17544 R-MMU-1237045 https://reactome.org/PathwayBrowser/#/R-MMU-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Mus musculus 17544 R-MMU-1237047 https://reactome.org/PathwayBrowser/#/R-MMU-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Mus musculus 17544 R-MMU-1237059 https://reactome.org/PathwayBrowser/#/R-MMU-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Mus musculus 17544 R-MMU-1237081 https://reactome.org/PathwayBrowser/#/R-MMU-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Mus musculus 17544 R-MMU-1247665 https://reactome.org/PathwayBrowser/#/R-MMU-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Mus musculus 17544 R-MMU-1475017 https://reactome.org/PathwayBrowser/#/R-MMU-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Mus musculus 17544 R-MMU-1475022 https://reactome.org/PathwayBrowser/#/R-MMU-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Mus musculus 17544 R-MMU-1475025 https://reactome.org/PathwayBrowser/#/R-MMU-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Mus musculus 17544 R-MMU-1475026 https://reactome.org/PathwayBrowser/#/R-MMU-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Mus musculus 17544 R-MMU-1475028 https://reactome.org/PathwayBrowser/#/R-MMU-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Mus musculus 17544 R-MMU-1475032 https://reactome.org/PathwayBrowser/#/R-MMU-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Mus musculus 17544 R-MMU-1475435 https://reactome.org/PathwayBrowser/#/R-MMU-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Mus musculus 17544 R-MMU-1475436 https://reactome.org/PathwayBrowser/#/R-MMU-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Mus musculus 17544 R-MMU-200555 https://reactome.org/PathwayBrowser/#/R-MMU-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Mus musculus 17544 R-MMU-2752067 https://reactome.org/PathwayBrowser/#/R-MMU-2752067 BESTs transport cytosolic HCO3- to extracellular region IEA Mus musculus 17544 R-MMU-383190 https://reactome.org/PathwayBrowser/#/R-MMU-383190 HCO3- transport through ion channel IEA Mus musculus 17544 R-MMU-425482 https://reactome.org/PathwayBrowser/#/R-MMU-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Mus musculus 17544 R-MMU-425483 https://reactome.org/PathwayBrowser/#/R-MMU-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Mus musculus 17544 R-MMU-425577 https://reactome.org/PathwayBrowser/#/R-MMU-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Mus musculus 17544 R-MMU-427666 https://reactome.org/PathwayBrowser/#/R-MMU-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Mus musculus 17544 R-MMU-508308 https://reactome.org/PathwayBrowser/#/R-MMU-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Mus musculus 17544 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 17544 R-MMU-70555 https://reactome.org/PathwayBrowser/#/R-MMU-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Mus musculus 17544 R-MMU-70773 https://reactome.org/PathwayBrowser/#/R-MMU-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Mus musculus 17544 R-MMU-73577 https://reactome.org/PathwayBrowser/#/R-MMU-73577 CAD hexamer transforms L-Gln to CAP IEA Mus musculus 17544 R-MMU-75851 https://reactome.org/PathwayBrowser/#/R-MMU-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 17544 R-MMU-8876889 https://reactome.org/PathwayBrowser/#/R-MMU-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 17544 R-MMU-8878664 https://reactome.org/PathwayBrowser/#/R-MMU-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Mus musculus 17544 R-MMU-9663359 https://reactome.org/PathwayBrowser/#/R-MMU-9663359 Slc26a5 changes conformation in response to depolarization TAS Mus musculus 17544 R-PFA-1475022 https://reactome.org/PathwayBrowser/#/R-PFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Plasmodium falciparum 17544 R-PFA-1475026 https://reactome.org/PathwayBrowser/#/R-PFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Plasmodium falciparum 17544 R-PFA-1475028 https://reactome.org/PathwayBrowser/#/R-PFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Plasmodium falciparum 17544 R-PFA-1475032 https://reactome.org/PathwayBrowser/#/R-PFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Plasmodium falciparum 17544 R-PFA-1475435 https://reactome.org/PathwayBrowser/#/R-PFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Plasmodium falciparum 17544 R-PFA-1475436 https://reactome.org/PathwayBrowser/#/R-PFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Plasmodium falciparum 17544 R-PFA-200555 https://reactome.org/PathwayBrowser/#/R-PFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Plasmodium falciparum 17544 R-PFA-383190 https://reactome.org/PathwayBrowser/#/R-PFA-383190 HCO3- transport through ion channel IEA Plasmodium falciparum 17544 R-PFA-73577 https://reactome.org/PathwayBrowser/#/R-PFA-73577 CAD hexamer transforms L-Gln to CAP IEA Plasmodium falciparum 17544 R-PFA-75851 https://reactome.org/PathwayBrowser/#/R-PFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 17544 R-PFA-8876889 https://reactome.org/PathwayBrowser/#/R-PFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 17544 R-RNO-1237038 https://reactome.org/PathwayBrowser/#/R-RNO-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Rattus norvegicus 17544 R-RNO-1237045 https://reactome.org/PathwayBrowser/#/R-RNO-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Rattus norvegicus 17544 R-RNO-1237047 https://reactome.org/PathwayBrowser/#/R-RNO-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Rattus norvegicus 17544 R-RNO-1237059 https://reactome.org/PathwayBrowser/#/R-RNO-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Rattus norvegicus 17544 R-RNO-1237081 https://reactome.org/PathwayBrowser/#/R-RNO-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Rattus norvegicus 17544 R-RNO-1247665 https://reactome.org/PathwayBrowser/#/R-RNO-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Rattus norvegicus 17544 R-RNO-1475017 https://reactome.org/PathwayBrowser/#/R-RNO-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Rattus norvegicus 17544 R-RNO-1475022 https://reactome.org/PathwayBrowser/#/R-RNO-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Rattus norvegicus 17544 R-RNO-1475025 https://reactome.org/PathwayBrowser/#/R-RNO-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Rattus norvegicus 17544 R-RNO-1475026 https://reactome.org/PathwayBrowser/#/R-RNO-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Rattus norvegicus 17544 R-RNO-1475028 https://reactome.org/PathwayBrowser/#/R-RNO-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Rattus norvegicus 17544 R-RNO-1475032 https://reactome.org/PathwayBrowser/#/R-RNO-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Rattus norvegicus 17544 R-RNO-1475435 https://reactome.org/PathwayBrowser/#/R-RNO-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Rattus norvegicus 17544 R-RNO-1475436 https://reactome.org/PathwayBrowser/#/R-RNO-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Rattus norvegicus 17544 R-RNO-200555 https://reactome.org/PathwayBrowser/#/R-RNO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Rattus norvegicus 17544 R-RNO-2752067 https://reactome.org/PathwayBrowser/#/R-RNO-2752067 BESTs transport cytosolic HCO3- to extracellular region IEA Rattus norvegicus 17544 R-RNO-383190 https://reactome.org/PathwayBrowser/#/R-RNO-383190 HCO3- transport through ion channel IEA Rattus norvegicus 17544 R-RNO-425482 https://reactome.org/PathwayBrowser/#/R-RNO-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Rattus norvegicus 17544 R-RNO-425483 https://reactome.org/PathwayBrowser/#/R-RNO-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Rattus norvegicus 17544 R-RNO-425577 https://reactome.org/PathwayBrowser/#/R-RNO-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Rattus norvegicus 17544 R-RNO-427666 https://reactome.org/PathwayBrowser/#/R-RNO-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Rattus norvegicus 17544 R-RNO-508308 https://reactome.org/PathwayBrowser/#/R-RNO-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Rattus norvegicus 17544 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 17544 R-RNO-70555 https://reactome.org/PathwayBrowser/#/R-RNO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Rattus norvegicus 17544 R-RNO-70773 https://reactome.org/PathwayBrowser/#/R-RNO-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Rattus norvegicus 17544 R-RNO-73577 https://reactome.org/PathwayBrowser/#/R-RNO-73577 CAD hexamer transforms L-Gln to CAP IEA Rattus norvegicus 17544 R-RNO-75851 https://reactome.org/PathwayBrowser/#/R-RNO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 17544 R-RNO-8876889 https://reactome.org/PathwayBrowser/#/R-RNO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 17544 R-RNO-8878664 https://reactome.org/PathwayBrowser/#/R-RNO-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Rattus norvegicus 17544 R-RNO-9667710 https://reactome.org/PathwayBrowser/#/R-RNO-9667710 Slc26a5 changes conformation in response to depolarization TAS Rattus norvegicus 17544 R-SCE-200555 https://reactome.org/PathwayBrowser/#/R-SCE-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Saccharomyces cerevisiae 17544 R-SCE-427666 https://reactome.org/PathwayBrowser/#/R-SCE-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Saccharomyces cerevisiae 17544 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 17544 R-SCE-70555 https://reactome.org/PathwayBrowser/#/R-SCE-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Saccharomyces cerevisiae 17544 R-SCE-73577 https://reactome.org/PathwayBrowser/#/R-SCE-73577 CAD hexamer transforms L-Gln to CAP IEA Saccharomyces cerevisiae 17544 R-SCE-75851 https://reactome.org/PathwayBrowser/#/R-SCE-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 17544 R-SCE-8876889 https://reactome.org/PathwayBrowser/#/R-SCE-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 17544 R-SPO-200555 https://reactome.org/PathwayBrowser/#/R-SPO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Schizosaccharomyces pombe 17544 R-SPO-427666 https://reactome.org/PathwayBrowser/#/R-SPO-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Schizosaccharomyces pombe 17544 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 17544 R-SPO-70555 https://reactome.org/PathwayBrowser/#/R-SPO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Schizosaccharomyces pombe 17544 R-SPO-73577 https://reactome.org/PathwayBrowser/#/R-SPO-73577 CAD hexamer transforms L-Gln to CAP IEA Schizosaccharomyces pombe 17544 R-SPO-75851 https://reactome.org/PathwayBrowser/#/R-SPO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 17544 R-SPO-8876889 https://reactome.org/PathwayBrowser/#/R-SPO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 17544 R-SSC-1237038 https://reactome.org/PathwayBrowser/#/R-SSC-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Sus scrofa 17544 R-SSC-1237045 https://reactome.org/PathwayBrowser/#/R-SSC-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Sus scrofa 17544 R-SSC-1237047 https://reactome.org/PathwayBrowser/#/R-SSC-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Sus scrofa 17544 R-SSC-1237059 https://reactome.org/PathwayBrowser/#/R-SSC-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Sus scrofa 17544 R-SSC-1237081 https://reactome.org/PathwayBrowser/#/R-SSC-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Sus scrofa 17544 R-SSC-1247665 https://reactome.org/PathwayBrowser/#/R-SSC-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Sus scrofa 17544 R-SSC-1475017 https://reactome.org/PathwayBrowser/#/R-SSC-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Sus scrofa 17544 R-SSC-1475022 https://reactome.org/PathwayBrowser/#/R-SSC-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Sus scrofa 17544 R-SSC-1475025 https://reactome.org/PathwayBrowser/#/R-SSC-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Sus scrofa 17544 R-SSC-1475026 https://reactome.org/PathwayBrowser/#/R-SSC-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Sus scrofa 17544 R-SSC-1475028 https://reactome.org/PathwayBrowser/#/R-SSC-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Sus scrofa 17544 R-SSC-1475032 https://reactome.org/PathwayBrowser/#/R-SSC-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Sus scrofa 17544 R-SSC-1475435 https://reactome.org/PathwayBrowser/#/R-SSC-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Sus scrofa 17544 R-SSC-1475436 https://reactome.org/PathwayBrowser/#/R-SSC-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Sus scrofa 17544 R-SSC-200555 https://reactome.org/PathwayBrowser/#/R-SSC-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Sus scrofa 17544 R-SSC-2752067 https://reactome.org/PathwayBrowser/#/R-SSC-2752067 BESTs transport cytosolic HCO3- to extracellular region IEA Sus scrofa 17544 R-SSC-383190 https://reactome.org/PathwayBrowser/#/R-SSC-383190 HCO3- transport through ion channel IEA Sus scrofa 17544 R-SSC-425482 https://reactome.org/PathwayBrowser/#/R-SSC-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Sus scrofa 17544 R-SSC-425483 https://reactome.org/PathwayBrowser/#/R-SSC-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Sus scrofa 17544 R-SSC-425577 https://reactome.org/PathwayBrowser/#/R-SSC-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Sus scrofa 17544 R-SSC-427666 https://reactome.org/PathwayBrowser/#/R-SSC-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Sus scrofa 17544 R-SSC-508308 https://reactome.org/PathwayBrowser/#/R-SSC-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Sus scrofa 17544 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 17544 R-SSC-70555 https://reactome.org/PathwayBrowser/#/R-SSC-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Sus scrofa 17544 R-SSC-70773 https://reactome.org/PathwayBrowser/#/R-SSC-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Sus scrofa 17544 R-SSC-73577 https://reactome.org/PathwayBrowser/#/R-SSC-73577 CAD hexamer transforms L-Gln to CAP IEA Sus scrofa 17544 R-SSC-75851 https://reactome.org/PathwayBrowser/#/R-SSC-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 17544 R-SSC-8876889 https://reactome.org/PathwayBrowser/#/R-SSC-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 17544 R-SSC-8878664 https://reactome.org/PathwayBrowser/#/R-SSC-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Sus scrofa 17544 R-XTR-1237038 https://reactome.org/PathwayBrowser/#/R-XTR-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Xenopus tropicalis 17544 R-XTR-1237047 https://reactome.org/PathwayBrowser/#/R-XTR-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Xenopus tropicalis 17544 R-XTR-1237059 https://reactome.org/PathwayBrowser/#/R-XTR-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Xenopus tropicalis 17544 R-XTR-1247665 https://reactome.org/PathwayBrowser/#/R-XTR-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Xenopus tropicalis 17544 R-XTR-1475017 https://reactome.org/PathwayBrowser/#/R-XTR-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Xenopus tropicalis 17544 R-XTR-1475022 https://reactome.org/PathwayBrowser/#/R-XTR-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Xenopus tropicalis 17544 R-XTR-1475025 https://reactome.org/PathwayBrowser/#/R-XTR-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Xenopus tropicalis 17544 R-XTR-1475026 https://reactome.org/PathwayBrowser/#/R-XTR-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Xenopus tropicalis 17544 R-XTR-1475028 https://reactome.org/PathwayBrowser/#/R-XTR-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Xenopus tropicalis 17544 R-XTR-1475032 https://reactome.org/PathwayBrowser/#/R-XTR-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Xenopus tropicalis 17544 R-XTR-1475435 https://reactome.org/PathwayBrowser/#/R-XTR-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Xenopus tropicalis 17544 R-XTR-1475436 https://reactome.org/PathwayBrowser/#/R-XTR-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Xenopus tropicalis 17544 R-XTR-200555 https://reactome.org/PathwayBrowser/#/R-XTR-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Xenopus tropicalis 17544 R-XTR-2752067 https://reactome.org/PathwayBrowser/#/R-XTR-2752067 BESTs transport cytosolic HCO3- to extracellular region IEA Xenopus tropicalis 17544 R-XTR-383190 https://reactome.org/PathwayBrowser/#/R-XTR-383190 HCO3- transport through ion channel IEA Xenopus tropicalis 17544 R-XTR-425482 https://reactome.org/PathwayBrowser/#/R-XTR-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Xenopus tropicalis 17544 R-XTR-425483 https://reactome.org/PathwayBrowser/#/R-XTR-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Xenopus tropicalis 17544 R-XTR-425577 https://reactome.org/PathwayBrowser/#/R-XTR-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Xenopus tropicalis 17544 R-XTR-427666 https://reactome.org/PathwayBrowser/#/R-XTR-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Xenopus tropicalis 17544 R-XTR-508308 https://reactome.org/PathwayBrowser/#/R-XTR-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Xenopus tropicalis 17544 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 17544 R-XTR-70555 https://reactome.org/PathwayBrowser/#/R-XTR-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Xenopus tropicalis 17544 R-XTR-70773 https://reactome.org/PathwayBrowser/#/R-XTR-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Xenopus tropicalis 17544 R-XTR-73577 https://reactome.org/PathwayBrowser/#/R-XTR-73577 CAD hexamer transforms L-Gln to CAP IEA Xenopus tropicalis 17544 R-XTR-75851 https://reactome.org/PathwayBrowser/#/R-XTR-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 17544 R-XTR-8876889 https://reactome.org/PathwayBrowser/#/R-XTR-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 17544 R-XTR-8878664 https://reactome.org/PathwayBrowser/#/R-XTR-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Xenopus tropicalis 17552 R-BTA-114552 https://reactome.org/PathwayBrowser/#/R-BTA-114552 Thrombin-activated PARs activate G12/13 IEA Bos taurus 17552 R-BTA-114558 https://reactome.org/PathwayBrowser/#/R-BTA-114558 Thrombin-activated PARs activate Gq IEA Bos taurus 17552 R-BTA-170674 https://reactome.org/PathwayBrowser/#/R-BTA-170674 Dissociation of the Gi alpha:G olf complex IEA Bos taurus 17552 R-BTA-170686 https://reactome.org/PathwayBrowser/#/R-BTA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Bos taurus 17552 R-BTA-205039 https://reactome.org/PathwayBrowser/#/R-BTA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Bos taurus 17552 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 17552 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 17552 R-BTA-381727 https://reactome.org/PathwayBrowser/#/R-BTA-381727 RAP1A exchanges GDP for GTP IEA Bos taurus 17552 R-BTA-392187 https://reactome.org/PathwayBrowser/#/R-BTA-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Bos taurus 17552 R-BTA-392195 https://reactome.org/PathwayBrowser/#/R-BTA-392195 Gi activation by P2Y purinoceptor 12 IEA Bos taurus 17552 R-BTA-3928633 https://reactome.org/PathwayBrowser/#/R-BTA-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Bos taurus 17552 R-BTA-392870 https://reactome.org/PathwayBrowser/#/R-BTA-392870 Gs activation by prostacyclin receptor IEA Bos taurus 17552 R-BTA-396996 https://reactome.org/PathwayBrowser/#/R-BTA-396996 Thrombin-activated PARs binds G-protein Gq IEA Bos taurus 17552 R-BTA-416530 https://reactome.org/PathwayBrowser/#/R-BTA-416530 FFAR1:FFAR1 ligands activate Gq IEA Bos taurus 17552 R-BTA-416546 https://reactome.org/PathwayBrowser/#/R-BTA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Bos taurus 17552 R-BTA-416588 https://reactome.org/PathwayBrowser/#/R-BTA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Bos taurus 17552 R-BTA-418574 https://reactome.org/PathwayBrowser/#/R-BTA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Bos taurus 17552 R-BTA-418582 https://reactome.org/PathwayBrowser/#/R-BTA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Bos taurus 17552 R-BTA-419166 https://reactome.org/PathwayBrowser/#/R-BTA-419166 GEFs activate RhoA,B,C IEA Bos taurus 17552 R-BTA-420883 https://reactome.org/PathwayBrowser/#/R-BTA-420883 Opsins act as GEFs for G alpha-t IEA Bos taurus 17552 R-BTA-428749 https://reactome.org/PathwayBrowser/#/R-BTA-428749 Activated TP receptor binds G-proten Gq IEA Bos taurus 17552 R-BTA-428750 https://reactome.org/PathwayBrowser/#/R-BTA-428750 Gq activation by TP receptor IEA Bos taurus 17552 R-BTA-428909 https://reactome.org/PathwayBrowser/#/R-BTA-428909 Activated TP receptor binds G-protein G13 IEA Bos taurus 17552 R-BTA-428917 https://reactome.org/PathwayBrowser/#/R-BTA-428917 G13 activation by TP receptor IEA Bos taurus 17552 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 17552 R-BTA-5638006 https://reactome.org/PathwayBrowser/#/R-BTA-5638006 ARL3 hydrolyzes GTP IEA Bos taurus 17552 R-BTA-5638016 https://reactome.org/PathwayBrowser/#/R-BTA-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Bos taurus 17552 R-BTA-749446 https://reactome.org/PathwayBrowser/#/R-BTA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Bos taurus 17552 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 17552 R-BTA-749453 https://reactome.org/PathwayBrowser/#/R-BTA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Bos taurus 17552 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 17552 R-BTA-750988 https://reactome.org/PathwayBrowser/#/R-BTA-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Bos taurus 17552 R-BTA-750993 https://reactome.org/PathwayBrowser/#/R-BTA-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Bos taurus 17552 R-BTA-751001 https://reactome.org/PathwayBrowser/#/R-BTA-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Bos taurus 17552 R-BTA-751027 https://reactome.org/PathwayBrowser/#/R-BTA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Bos taurus 17552 R-BTA-751029 https://reactome.org/PathwayBrowser/#/R-BTA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Bos taurus 17552 R-BTA-751039 https://reactome.org/PathwayBrowser/#/R-BTA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Bos taurus 17552 R-BTA-77081 https://reactome.org/PathwayBrowser/#/R-BTA-77081 Formation of the CE:GMP intermediate complex IEA Bos taurus 17552 R-BTA-8854329 https://reactome.org/PathwayBrowser/#/R-BTA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Bos taurus 17552 R-BTA-8854604 https://reactome.org/PathwayBrowser/#/R-BTA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Bos taurus 17552 R-BTA-8982012 https://reactome.org/PathwayBrowser/#/R-BTA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Bos taurus 17552 R-BTA-8982018 https://reactome.org/PathwayBrowser/#/R-BTA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Bos taurus 17552 R-BTA-8982026 https://reactome.org/PathwayBrowser/#/R-BTA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Bos taurus 17552 R-BTA-8982637 https://reactome.org/PathwayBrowser/#/R-BTA-8982637 Opsins binds G alpha-t IEA Bos taurus 17552 R-BTA-9021596 https://reactome.org/PathwayBrowser/#/R-BTA-9021596 Membrane estrogen receptors bind SRC IEA Bos taurus 17552 R-BTA-9021600 https://reactome.org/PathwayBrowser/#/R-BTA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Bos taurus 17552 R-BTA-9021601 https://reactome.org/PathwayBrowser/#/R-BTA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Bos taurus 17552 R-CEL-114552 https://reactome.org/PathwayBrowser/#/R-CEL-114552 Thrombin-activated PARs activate G12/13 IEA Caenorhabditis elegans 17552 R-CEL-114558 https://reactome.org/PathwayBrowser/#/R-CEL-114558 Thrombin-activated PARs activate Gq IEA Caenorhabditis elegans 17552 R-CEL-170674 https://reactome.org/PathwayBrowser/#/R-CEL-170674 Dissociation of the Gi alpha:G olf complex IEA Caenorhabditis elegans 17552 R-CEL-170686 https://reactome.org/PathwayBrowser/#/R-CEL-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Caenorhabditis elegans 17552 R-CEL-205039 https://reactome.org/PathwayBrowser/#/R-CEL-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Caenorhabditis elegans 17552 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 17552 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 17552 R-CEL-381727 https://reactome.org/PathwayBrowser/#/R-CEL-381727 RAP1A exchanges GDP for GTP IEA Caenorhabditis elegans 17552 R-CEL-392195 https://reactome.org/PathwayBrowser/#/R-CEL-392195 Gi activation by P2Y purinoceptor 12 IEA Caenorhabditis elegans 17552 R-CEL-3928612 https://reactome.org/PathwayBrowser/#/R-CEL-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 17552 R-CEL-3928633 https://reactome.org/PathwayBrowser/#/R-CEL-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Caenorhabditis elegans 17552 R-CEL-396996 https://reactome.org/PathwayBrowser/#/R-CEL-396996 Thrombin-activated PARs binds G-protein Gq IEA Caenorhabditis elegans 17552 R-CEL-416546 https://reactome.org/PathwayBrowser/#/R-CEL-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Caenorhabditis elegans 17552 R-CEL-416588 https://reactome.org/PathwayBrowser/#/R-CEL-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Caenorhabditis elegans 17552 R-CEL-418574 https://reactome.org/PathwayBrowser/#/R-CEL-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Caenorhabditis elegans 17552 R-CEL-418582 https://reactome.org/PathwayBrowser/#/R-CEL-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Caenorhabditis elegans 17552 R-CEL-419166 https://reactome.org/PathwayBrowser/#/R-CEL-419166 GEFs activate RhoA,B,C IEA Caenorhabditis elegans 17552 R-CEL-420883 https://reactome.org/PathwayBrowser/#/R-CEL-420883 Opsins act as GEFs for G alpha-t IEA Caenorhabditis elegans 17552 R-CEL-428750 https://reactome.org/PathwayBrowser/#/R-CEL-428750 Gq activation by TP receptor IEA Caenorhabditis elegans 17552 R-CEL-428917 https://reactome.org/PathwayBrowser/#/R-CEL-428917 G13 activation by TP receptor IEA Caenorhabditis elegans 17552 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 17552 R-CEL-5638006 https://reactome.org/PathwayBrowser/#/R-CEL-5638006 ARL3 hydrolyzes GTP IEA Caenorhabditis elegans 17552 R-CEL-5638016 https://reactome.org/PathwayBrowser/#/R-CEL-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Caenorhabditis elegans 17552 R-CEL-749446 https://reactome.org/PathwayBrowser/#/R-CEL-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Caenorhabditis elegans 17552 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 17552 R-CEL-749453 https://reactome.org/PathwayBrowser/#/R-CEL-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Caenorhabditis elegans 17552 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 17552 R-CEL-750988 https://reactome.org/PathwayBrowser/#/R-CEL-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Caenorhabditis elegans 17552 R-CEL-750993 https://reactome.org/PathwayBrowser/#/R-CEL-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Caenorhabditis elegans 17552 R-CEL-751001 https://reactome.org/PathwayBrowser/#/R-CEL-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Caenorhabditis elegans 17552 R-CEL-751027 https://reactome.org/PathwayBrowser/#/R-CEL-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Caenorhabditis elegans 17552 R-CEL-751029 https://reactome.org/PathwayBrowser/#/R-CEL-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Caenorhabditis elegans 17552 R-CEL-751039 https://reactome.org/PathwayBrowser/#/R-CEL-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Caenorhabditis elegans 17552 R-CEL-77081 https://reactome.org/PathwayBrowser/#/R-CEL-77081 Formation of the CE:GMP intermediate complex IEA Caenorhabditis elegans 17552 R-CEL-8854329 https://reactome.org/PathwayBrowser/#/R-CEL-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 17552 R-CEL-8982012 https://reactome.org/PathwayBrowser/#/R-CEL-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Caenorhabditis elegans 17552 R-CEL-8982018 https://reactome.org/PathwayBrowser/#/R-CEL-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Caenorhabditis elegans 17552 R-CEL-8982026 https://reactome.org/PathwayBrowser/#/R-CEL-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Caenorhabditis elegans 17552 R-CFA-114552 https://reactome.org/PathwayBrowser/#/R-CFA-114552 Thrombin-activated PARs activate G12/13 IEA Canis familiaris 17552 R-CFA-114558 https://reactome.org/PathwayBrowser/#/R-CFA-114558 Thrombin-activated PARs activate Gq IEA Canis familiaris 17552 R-CFA-170674 https://reactome.org/PathwayBrowser/#/R-CFA-170674 Dissociation of the Gi alpha:G olf complex IEA Canis familiaris 17552 R-CFA-170686 https://reactome.org/PathwayBrowser/#/R-CFA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Canis familiaris 17552 R-CFA-205039 https://reactome.org/PathwayBrowser/#/R-CFA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Canis familiaris 17552 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 17552 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 17552 R-CFA-381727 https://reactome.org/PathwayBrowser/#/R-CFA-381727 RAP1A exchanges GDP for GTP IEA Canis familiaris 17552 R-CFA-392187 https://reactome.org/PathwayBrowser/#/R-CFA-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Canis familiaris 17552 R-CFA-392195 https://reactome.org/PathwayBrowser/#/R-CFA-392195 Gi activation by P2Y purinoceptor 12 IEA Canis familiaris 17552 R-CFA-3928612 https://reactome.org/PathwayBrowser/#/R-CFA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 17552 R-CFA-3928633 https://reactome.org/PathwayBrowser/#/R-CFA-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Canis familiaris 17552 R-CFA-392870 https://reactome.org/PathwayBrowser/#/R-CFA-392870 Gs activation by prostacyclin receptor IEA Canis familiaris 17552 R-CFA-396996 https://reactome.org/PathwayBrowser/#/R-CFA-396996 Thrombin-activated PARs binds G-protein Gq IEA Canis familiaris 17552 R-CFA-416530 https://reactome.org/PathwayBrowser/#/R-CFA-416530 FFAR1:FFAR1 ligands activate Gq IEA Canis familiaris 17552 R-CFA-416546 https://reactome.org/PathwayBrowser/#/R-CFA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Canis familiaris 17552 R-CFA-416588 https://reactome.org/PathwayBrowser/#/R-CFA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Canis familiaris 17552 R-CFA-418574 https://reactome.org/PathwayBrowser/#/R-CFA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Canis familiaris 17552 R-CFA-418582 https://reactome.org/PathwayBrowser/#/R-CFA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Canis familiaris 17552 R-CFA-419166 https://reactome.org/PathwayBrowser/#/R-CFA-419166 GEFs activate RhoA,B,C IEA Canis familiaris 17552 R-CFA-420883 https://reactome.org/PathwayBrowser/#/R-CFA-420883 Opsins act as GEFs for G alpha-t IEA Canis familiaris 17552 R-CFA-428749 https://reactome.org/PathwayBrowser/#/R-CFA-428749 Activated TP receptor binds G-proten Gq IEA Canis familiaris 17552 R-CFA-428750 https://reactome.org/PathwayBrowser/#/R-CFA-428750 Gq activation by TP receptor IEA Canis familiaris 17552 R-CFA-428909 https://reactome.org/PathwayBrowser/#/R-CFA-428909 Activated TP receptor binds G-protein G13 IEA Canis familiaris 17552 R-CFA-428917 https://reactome.org/PathwayBrowser/#/R-CFA-428917 G13 activation by TP receptor IEA Canis familiaris 17552 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 17552 R-CFA-5638006 https://reactome.org/PathwayBrowser/#/R-CFA-5638006 ARL3 hydrolyzes GTP IEA Canis familiaris 17552 R-CFA-5638016 https://reactome.org/PathwayBrowser/#/R-CFA-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Canis familiaris 17552 R-CFA-749446 https://reactome.org/PathwayBrowser/#/R-CFA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Canis familiaris 17552 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 17552 R-CFA-749453 https://reactome.org/PathwayBrowser/#/R-CFA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Canis familiaris 17552 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 17552 R-CFA-750988 https://reactome.org/PathwayBrowser/#/R-CFA-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Canis familiaris 17552 R-CFA-750993 https://reactome.org/PathwayBrowser/#/R-CFA-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Canis familiaris 17552 R-CFA-751001 https://reactome.org/PathwayBrowser/#/R-CFA-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Canis familiaris 17552 R-CFA-751027 https://reactome.org/PathwayBrowser/#/R-CFA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Canis familiaris 17552 R-CFA-751029 https://reactome.org/PathwayBrowser/#/R-CFA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Canis familiaris 17552 R-CFA-751039 https://reactome.org/PathwayBrowser/#/R-CFA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Canis familiaris 17552 R-CFA-77081 https://reactome.org/PathwayBrowser/#/R-CFA-77081 Formation of the CE:GMP intermediate complex IEA Canis familiaris 17552 R-CFA-8854329 https://reactome.org/PathwayBrowser/#/R-CFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 17552 R-CFA-8854604 https://reactome.org/PathwayBrowser/#/R-CFA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Canis familiaris 17552 R-CFA-8982012 https://reactome.org/PathwayBrowser/#/R-CFA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Canis familiaris 17552 R-CFA-8982018 https://reactome.org/PathwayBrowser/#/R-CFA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Canis familiaris 17552 R-CFA-8982026 https://reactome.org/PathwayBrowser/#/R-CFA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Canis familiaris 17552 R-CFA-8982637 https://reactome.org/PathwayBrowser/#/R-CFA-8982637 Opsins binds G alpha-t IEA Canis familiaris 17552 R-CFA-9021596 https://reactome.org/PathwayBrowser/#/R-CFA-9021596 Membrane estrogen receptors bind SRC IEA Canis familiaris 17552 R-CFA-9021600 https://reactome.org/PathwayBrowser/#/R-CFA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Canis familiaris 17552 R-CFA-9021601 https://reactome.org/PathwayBrowser/#/R-CFA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Canis familiaris 17552 R-DDI-170674 https://reactome.org/PathwayBrowser/#/R-DDI-170674 Dissociation of the Gi alpha:G olf complex IEA Dictyostelium discoideum 17552 R-DDI-170686 https://reactome.org/PathwayBrowser/#/R-DDI-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Dictyostelium discoideum 17552 R-DDI-205039 https://reactome.org/PathwayBrowser/#/R-DDI-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Dictyostelium discoideum 17552 R-DDI-380073 https://reactome.org/PathwayBrowser/#/R-DDI-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Dictyostelium discoideum 17552 R-DDI-381727 https://reactome.org/PathwayBrowser/#/R-DDI-381727 RAP1A exchanges GDP for GTP IEA Dictyostelium discoideum 17552 R-DDI-418574 https://reactome.org/PathwayBrowser/#/R-DDI-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Dictyostelium discoideum 17552 R-DDI-418582 https://reactome.org/PathwayBrowser/#/R-DDI-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Dictyostelium discoideum 17552 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 17552 R-DDI-77081 https://reactome.org/PathwayBrowser/#/R-DDI-77081 Formation of the CE:GMP intermediate complex IEA Dictyostelium discoideum 17552 R-DDI-8854329 https://reactome.org/PathwayBrowser/#/R-DDI-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 17552 R-DDI-8854604 https://reactome.org/PathwayBrowser/#/R-DDI-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Dictyostelium discoideum 17552 R-DDI-8982012 https://reactome.org/PathwayBrowser/#/R-DDI-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Dictyostelium discoideum 17552 R-DDI-8982018 https://reactome.org/PathwayBrowser/#/R-DDI-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Dictyostelium discoideum 17552 R-DDI-8982026 https://reactome.org/PathwayBrowser/#/R-DDI-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Dictyostelium discoideum 17552 R-DME-170674 https://reactome.org/PathwayBrowser/#/R-DME-170674 Dissociation of the Gi alpha:G olf complex IEA Drosophila melanogaster 17552 R-DME-170686 https://reactome.org/PathwayBrowser/#/R-DME-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Drosophila melanogaster 17552 R-DME-205039 https://reactome.org/PathwayBrowser/#/R-DME-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Drosophila melanogaster 17552 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 17552 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 17552 R-DME-381727 https://reactome.org/PathwayBrowser/#/R-DME-381727 RAP1A exchanges GDP for GTP IEA Drosophila melanogaster 17552 R-DME-392195 https://reactome.org/PathwayBrowser/#/R-DME-392195 Gi activation by P2Y purinoceptor 12 IEA Drosophila melanogaster 17552 R-DME-3928612 https://reactome.org/PathwayBrowser/#/R-DME-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 17552 R-DME-3928633 https://reactome.org/PathwayBrowser/#/R-DME-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Drosophila melanogaster 17552 R-DME-392870 https://reactome.org/PathwayBrowser/#/R-DME-392870 Gs activation by prostacyclin receptor IEA Drosophila melanogaster 17552 R-DME-416588 https://reactome.org/PathwayBrowser/#/R-DME-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Drosophila melanogaster 17552 R-DME-418574 https://reactome.org/PathwayBrowser/#/R-DME-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Drosophila melanogaster 17552 R-DME-418582 https://reactome.org/PathwayBrowser/#/R-DME-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Drosophila melanogaster 17552 R-DME-419166 https://reactome.org/PathwayBrowser/#/R-DME-419166 GEFs activate RhoA,B,C IEA Drosophila melanogaster 17552 R-DME-428749 https://reactome.org/PathwayBrowser/#/R-DME-428749 Activated TP receptor binds G-proten Gq IEA Drosophila melanogaster 17552 R-DME-428750 https://reactome.org/PathwayBrowser/#/R-DME-428750 Gq activation by TP receptor IEA Drosophila melanogaster 17552 R-DME-428909 https://reactome.org/PathwayBrowser/#/R-DME-428909 Activated TP receptor binds G-protein G13 IEA Drosophila melanogaster 17552 R-DME-428917 https://reactome.org/PathwayBrowser/#/R-DME-428917 G13 activation by TP receptor IEA Drosophila melanogaster 17552 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 17552 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 17552 R-DME-749453 https://reactome.org/PathwayBrowser/#/R-DME-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Drosophila melanogaster 17552 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 17552 R-DME-750993 https://reactome.org/PathwayBrowser/#/R-DME-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Drosophila melanogaster 17552 R-DME-751001 https://reactome.org/PathwayBrowser/#/R-DME-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Drosophila melanogaster 17552 R-DME-751027 https://reactome.org/PathwayBrowser/#/R-DME-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Drosophila melanogaster 17552 R-DME-751029 https://reactome.org/PathwayBrowser/#/R-DME-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Drosophila melanogaster 17552 R-DME-751039 https://reactome.org/PathwayBrowser/#/R-DME-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Drosophila melanogaster 17552 R-DME-77081 https://reactome.org/PathwayBrowser/#/R-DME-77081 Formation of the CE:GMP intermediate complex IEA Drosophila melanogaster 17552 R-DME-8854329 https://reactome.org/PathwayBrowser/#/R-DME-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 17552 R-DME-8854604 https://reactome.org/PathwayBrowser/#/R-DME-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Drosophila melanogaster 17552 R-DME-8982012 https://reactome.org/PathwayBrowser/#/R-DME-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Drosophila melanogaster 17552 R-DME-8982026 https://reactome.org/PathwayBrowser/#/R-DME-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Drosophila melanogaster 17552 R-DME-9021596 https://reactome.org/PathwayBrowser/#/R-DME-9021596 Membrane estrogen receptors bind SRC IEA Drosophila melanogaster 17552 R-DME-9021600 https://reactome.org/PathwayBrowser/#/R-DME-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Drosophila melanogaster 17552 R-DME-9021601 https://reactome.org/PathwayBrowser/#/R-DME-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Drosophila melanogaster 17552 R-DRE-114558 https://reactome.org/PathwayBrowser/#/R-DRE-114558 Thrombin-activated PARs activate Gq IEA Danio rerio 17552 R-DRE-170674 https://reactome.org/PathwayBrowser/#/R-DRE-170674 Dissociation of the Gi alpha:G olf complex IEA Danio rerio 17552 R-DRE-170686 https://reactome.org/PathwayBrowser/#/R-DRE-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Danio rerio 17552 R-DRE-205039 https://reactome.org/PathwayBrowser/#/R-DRE-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Danio rerio 17552 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 17552 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 17552 R-DRE-381727 https://reactome.org/PathwayBrowser/#/R-DRE-381727 RAP1A exchanges GDP for GTP IEA Danio rerio 17552 R-DRE-392195 https://reactome.org/PathwayBrowser/#/R-DRE-392195 Gi activation by P2Y purinoceptor 12 IEA Danio rerio 17552 R-DRE-416546 https://reactome.org/PathwayBrowser/#/R-DRE-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Danio rerio 17552 R-DRE-416588 https://reactome.org/PathwayBrowser/#/R-DRE-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Danio rerio 17552 R-DRE-418574 https://reactome.org/PathwayBrowser/#/R-DRE-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Danio rerio 17552 R-DRE-418582 https://reactome.org/PathwayBrowser/#/R-DRE-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Danio rerio 17552 R-DRE-419166 https://reactome.org/PathwayBrowser/#/R-DRE-419166 GEFs activate RhoA,B,C IEA Danio rerio 17552 R-DRE-420883 https://reactome.org/PathwayBrowser/#/R-DRE-420883 Opsins act as GEFs for G alpha-t IEA Danio rerio 17552 R-DRE-428750 https://reactome.org/PathwayBrowser/#/R-DRE-428750 Gq activation by TP receptor IEA Danio rerio 17552 R-DRE-428917 https://reactome.org/PathwayBrowser/#/R-DRE-428917 G13 activation by TP receptor IEA Danio rerio 17552 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 17552 R-DRE-5638006 https://reactome.org/PathwayBrowser/#/R-DRE-5638006 ARL3 hydrolyzes GTP IEA Danio rerio 17552 R-DRE-5638016 https://reactome.org/PathwayBrowser/#/R-DRE-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Danio rerio 17552 R-DRE-77081 https://reactome.org/PathwayBrowser/#/R-DRE-77081 Formation of the CE:GMP intermediate complex IEA Danio rerio 17552 R-DRE-8854329 https://reactome.org/PathwayBrowser/#/R-DRE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Danio rerio 17552 R-DRE-8854604 https://reactome.org/PathwayBrowser/#/R-DRE-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Danio rerio 17552 R-DRE-8982012 https://reactome.org/PathwayBrowser/#/R-DRE-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Danio rerio 17552 R-DRE-8982026 https://reactome.org/PathwayBrowser/#/R-DRE-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Danio rerio 17552 R-DRE-9021596 https://reactome.org/PathwayBrowser/#/R-DRE-9021596 Membrane estrogen receptors bind SRC IEA Danio rerio 17552 R-GGA-114552 https://reactome.org/PathwayBrowser/#/R-GGA-114552 Thrombin-activated PARs activate G12/13 IEA Gallus gallus 17552 R-GGA-114558 https://reactome.org/PathwayBrowser/#/R-GGA-114558 Thrombin-activated PARs activate Gq IEA Gallus gallus 17552 R-GGA-170674 https://reactome.org/PathwayBrowser/#/R-GGA-170674 Dissociation of the Gi alpha:G olf complex IEA Gallus gallus 17552 R-GGA-170686 https://reactome.org/PathwayBrowser/#/R-GGA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Gallus gallus 17552 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus 17552 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 17552 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 17552 R-GGA-381727 https://reactome.org/PathwayBrowser/#/R-GGA-381727 RAP1A exchanges GDP for GTP IEA Gallus gallus 17552 R-GGA-392195 https://reactome.org/PathwayBrowser/#/R-GGA-392195 Gi activation by P2Y purinoceptor 12 IEA Gallus gallus 17552 R-GGA-3928612 https://reactome.org/PathwayBrowser/#/R-GGA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 17552 R-GGA-3928633 https://reactome.org/PathwayBrowser/#/R-GGA-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Gallus gallus 17552 R-GGA-396996 https://reactome.org/PathwayBrowser/#/R-GGA-396996 Thrombin-activated PARs binds G-protein Gq IEA Gallus gallus 17552 R-GGA-416588 https://reactome.org/PathwayBrowser/#/R-GGA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Gallus gallus 17552 R-GGA-418574 https://reactome.org/PathwayBrowser/#/R-GGA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Gallus gallus 17552 R-GGA-418582 https://reactome.org/PathwayBrowser/#/R-GGA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Gallus gallus 17552 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus 17552 R-GGA-420883 https://reactome.org/PathwayBrowser/#/R-GGA-420883 Opsins act as GEFs for G alpha-t IEA Gallus gallus 17552 R-GGA-428749 https://reactome.org/PathwayBrowser/#/R-GGA-428749 Activated TP receptor binds G-proten Gq IEA Gallus gallus 17552 R-GGA-428750 https://reactome.org/PathwayBrowser/#/R-GGA-428750 Gq activation by TP receptor IEA Gallus gallus 17552 R-GGA-428909 https://reactome.org/PathwayBrowser/#/R-GGA-428909 Activated TP receptor binds G-protein G13 IEA Gallus gallus 17552 R-GGA-428917 https://reactome.org/PathwayBrowser/#/R-GGA-428917 G13 activation by TP receptor IEA Gallus gallus 17552 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 17552 R-GGA-5638006 https://reactome.org/PathwayBrowser/#/R-GGA-5638006 ARL3 hydrolyzes GTP IEA Gallus gallus 17552 R-GGA-5638016 https://reactome.org/PathwayBrowser/#/R-GGA-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Gallus gallus 17552 R-GGA-749446 https://reactome.org/PathwayBrowser/#/R-GGA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Gallus gallus 17552 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 17552 R-GGA-749453 https://reactome.org/PathwayBrowser/#/R-GGA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Gallus gallus 17552 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 17552 R-GGA-750988 https://reactome.org/PathwayBrowser/#/R-GGA-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Gallus gallus 17552 R-GGA-750993 https://reactome.org/PathwayBrowser/#/R-GGA-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Gallus gallus 17552 R-GGA-751001 https://reactome.org/PathwayBrowser/#/R-GGA-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Gallus gallus 17552 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus 17552 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus 17552 R-GGA-751039 https://reactome.org/PathwayBrowser/#/R-GGA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Gallus gallus 17552 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus 17552 R-GGA-8854329 https://reactome.org/PathwayBrowser/#/R-GGA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 17552 R-GGA-8854604 https://reactome.org/PathwayBrowser/#/R-GGA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Gallus gallus 17552 R-GGA-8982012 https://reactome.org/PathwayBrowser/#/R-GGA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Gallus gallus 17552 R-GGA-8982018 https://reactome.org/PathwayBrowser/#/R-GGA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Gallus gallus 17552 R-GGA-8982026 https://reactome.org/PathwayBrowser/#/R-GGA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Gallus gallus 17552 R-GGA-8982637 https://reactome.org/PathwayBrowser/#/R-GGA-8982637 Opsins binds G alpha-t IEA Gallus gallus 17552 R-GGA-9021596 https://reactome.org/PathwayBrowser/#/R-GGA-9021596 Membrane estrogen receptors bind SRC IEA Gallus gallus 17552 R-GGA-9021600 https://reactome.org/PathwayBrowser/#/R-GGA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Gallus gallus 17552 R-GGA-9021601 https://reactome.org/PathwayBrowser/#/R-GGA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Gallus gallus 17552 R-HSA-114552 https://reactome.org/PathwayBrowser/#/R-HSA-114552 Thrombin-activated PARs activate G12/13 TAS Homo sapiens 17552 R-HSA-114558 https://reactome.org/PathwayBrowser/#/R-HSA-114558 Thrombin-activated PARs activate Gq TAS Homo sapiens 17552 R-HSA-1458485 https://reactome.org/PathwayBrowser/#/R-HSA-1458485 RALA hydrolyzes GTP IEA Homo sapiens 17552 R-HSA-170674 https://reactome.org/PathwayBrowser/#/R-HSA-170674 Dissociation of the Gi alpha:G olf complex TAS Homo sapiens 17552 R-HSA-170686 https://reactome.org/PathwayBrowser/#/R-HSA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha TAS Homo sapiens 17552 R-HSA-180687 https://reactome.org/PathwayBrowser/#/R-HSA-180687 Conversion of Ran-GDP to Ran-GTP TAS Homo sapiens 17552 R-HSA-1912349 https://reactome.org/PathwayBrowser/#/R-HSA-1912349 Fucosylation of Pre-NOTCH by POFUT1 IEA Homo sapiens 17552 R-HSA-205039 https://reactome.org/PathwayBrowser/#/R-HSA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor TAS Homo sapiens 17552 R-HSA-2255342 https://reactome.org/PathwayBrowser/#/R-HSA-2255342 RALA exchanges GDP for GTP IEA Homo sapiens 17552 R-HSA-2255343 https://reactome.org/PathwayBrowser/#/R-HSA-2255343 RAB8A,10,13,14 exchange GDP for GTP IEA Homo sapiens 17552 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 17552 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 17552 R-HSA-381727 https://reactome.org/PathwayBrowser/#/R-HSA-381727 RAP1A exchanges GDP for GTP TAS Homo sapiens 17552 R-HSA-392133 https://reactome.org/PathwayBrowser/#/R-HSA-392133 G alpha (z) auto-inactivates by hydrolysing GTP to GDP IEA Homo sapiens 17552 R-HSA-392187 https://reactome.org/PathwayBrowser/#/R-HSA-392187 Activated P2Y purinoceptor 12 binds G-protein Gi TAS Homo sapiens 17552 R-HSA-392195 https://reactome.org/PathwayBrowser/#/R-HSA-392195 Gi activation by P2Y purinoceptor 12 TAS Homo sapiens 17552 R-HSA-392212 https://reactome.org/PathwayBrowser/#/R-HSA-392212 G alpha (i) auto-inactivates by hydrolysing GTP to GDP IEA Homo sapiens 17552 R-HSA-3928612 https://reactome.org/PathwayBrowser/#/R-HSA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 17552 R-HSA-3928633 https://reactome.org/PathwayBrowser/#/R-HSA-3928633 bPIX exchanges GTP for GDP on RAC, activating it TAS Homo sapiens 17552 R-HSA-392870 https://reactome.org/PathwayBrowser/#/R-HSA-392870 Gs activation by prostacyclin receptor TAS Homo sapiens 17552 R-HSA-396941 https://reactome.org/PathwayBrowser/#/R-HSA-396941 Thrombin-activated PARs binds G-protein G12/13 IEA Homo sapiens 17552 R-HSA-396996 https://reactome.org/PathwayBrowser/#/R-HSA-396996 Thrombin-activated PARs binds G-protein Gq TAS Homo sapiens 17552 R-HSA-399935 https://reactome.org/PathwayBrowser/#/R-HSA-399935 Inactivation of R-Ras by Sema3A-Plexin-A GAP activity IEA Homo sapiens 17552 R-HSA-399995 https://reactome.org/PathwayBrowser/#/R-HSA-399995 Muscarinic Acetylcholine Receptor M3 activates Gq IEA Homo sapiens 17552 R-HSA-416530 https://reactome.org/PathwayBrowser/#/R-HSA-416530 FFAR1:FFAR1 ligands activate Gq TAS Homo sapiens 17552 R-HSA-416546 https://reactome.org/PathwayBrowser/#/R-HSA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity TAS Homo sapiens 17552 R-HSA-416588 https://reactome.org/PathwayBrowser/#/R-HSA-416588 Activation of Rho by LARG and PDZ-RhoGEF TAS Homo sapiens 17552 R-HSA-418574 https://reactome.org/PathwayBrowser/#/R-HSA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP TAS Homo sapiens 17552 R-HSA-418579 https://reactome.org/PathwayBrowser/#/R-HSA-418579 Gq activation by P2Y purinoceptor 1 IEA Homo sapiens 17552 R-HSA-418581 https://reactome.org/PathwayBrowser/#/R-HSA-418581 Activated P2Y purinoceptor 1 binds G-protein Gq IEA Homo sapiens 17552 R-HSA-418582 https://reactome.org/PathwayBrowser/#/R-HSA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP TAS Homo sapiens 17552 R-HSA-419166 https://reactome.org/PathwayBrowser/#/R-HSA-419166 GEFs activate RhoA,B,C TAS Homo sapiens 17552 R-HSA-420883 https://reactome.org/PathwayBrowser/#/R-HSA-420883 Opsins act as GEFs for G alpha-t TAS Homo sapiens 17552 R-HSA-428749 https://reactome.org/PathwayBrowser/#/R-HSA-428749 Activated TP receptor binds G-proten Gq TAS Homo sapiens 17552 R-HSA-428750 https://reactome.org/PathwayBrowser/#/R-HSA-428750 Gq activation by TP receptor TAS Homo sapiens 17552 R-HSA-428909 https://reactome.org/PathwayBrowser/#/R-HSA-428909 Activated TP receptor binds G-protein G13 TAS Homo sapiens 17552 R-HSA-428917 https://reactome.org/PathwayBrowser/#/R-HSA-428917 G13 activation by TP receptor TAS Homo sapiens 17552 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 17552 R-HSA-5218829 https://reactome.org/PathwayBrowser/#/R-HSA-5218829 VEGF induces CDC42 activation by unknown mechanism TAS Homo sapiens 17552 R-HSA-5638006 https://reactome.org/PathwayBrowser/#/R-HSA-5638006 ARL3 hydrolyzes GTP TAS Homo sapiens 17552 R-HSA-5638016 https://reactome.org/PathwayBrowser/#/R-HSA-5638016 RP2:ARL3:GDP:UNC119B dissociates TAS Homo sapiens 17552 R-HSA-749446 https://reactome.org/PathwayBrowser/#/R-HSA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz TAS Homo sapiens 17552 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 17552 R-HSA-749453 https://reactome.org/PathwayBrowser/#/R-HSA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz TAS Homo sapiens 17552 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 17552 R-HSA-750988 https://reactome.org/PathwayBrowser/#/R-HSA-750988 Inactive G alpha (z) reassociates with G beta:gamma TAS Homo sapiens 17552 R-HSA-750993 https://reactome.org/PathwayBrowser/#/R-HSA-750993 Inactive G alpha (q) reassociates with G beta:gamma TAS Homo sapiens 17552 R-HSA-751001 https://reactome.org/PathwayBrowser/#/R-HSA-751001 Inactive G alpha (i) reassociates with G beta:gamma TAS Homo sapiens 17552 R-HSA-751027 https://reactome.org/PathwayBrowser/#/R-HSA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 TAS Homo sapiens 17552 R-HSA-751029 https://reactome.org/PathwayBrowser/#/R-HSA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 TAS Homo sapiens 17552 R-HSA-751039 https://reactome.org/PathwayBrowser/#/R-HSA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma TAS Homo sapiens 17552 R-HSA-77081 https://reactome.org/PathwayBrowser/#/R-HSA-77081 Formation of the CE:GMP intermediate complex TAS Homo sapiens 17552 R-HSA-8854329 https://reactome.org/PathwayBrowser/#/R-HSA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 17552 R-HSA-8854604 https://reactome.org/PathwayBrowser/#/R-HSA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A TAS Homo sapiens 17552 R-HSA-8982012 https://reactome.org/PathwayBrowser/#/R-HSA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 TAS Homo sapiens 17552 R-HSA-8982018 https://reactome.org/PathwayBrowser/#/R-HSA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) TAS Homo sapiens 17552 R-HSA-8982026 https://reactome.org/PathwayBrowser/#/R-HSA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) TAS Homo sapiens 17552 R-HSA-8982637 https://reactome.org/PathwayBrowser/#/R-HSA-8982637 Opsins binds G alpha-t TAS Homo sapiens 17552 R-HSA-9021596 https://reactome.org/PathwayBrowser/#/R-HSA-9021596 Membrane estrogen receptors bind SRC TAS Homo sapiens 17552 R-HSA-9021600 https://reactome.org/PathwayBrowser/#/R-HSA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors TAS Homo sapiens 17552 R-HSA-9021601 https://reactome.org/PathwayBrowser/#/R-HSA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG TAS Homo sapiens 17552 R-MMU-114552 https://reactome.org/PathwayBrowser/#/R-MMU-114552 Thrombin-activated PARs activate G12/13 IEA Mus musculus 17552 R-MMU-114558 https://reactome.org/PathwayBrowser/#/R-MMU-114558 Thrombin-activated PARs activate Gq IEA Mus musculus 17552 R-MMU-1458501 https://reactome.org/PathwayBrowser/#/R-MMU-1458501 RalA Hydrolyzes GTP TAS Mus musculus 17552 R-MMU-170674 https://reactome.org/PathwayBrowser/#/R-MMU-170674 Dissociation of the Gi alpha:G olf complex IEA Mus musculus 17552 R-MMU-170686 https://reactome.org/PathwayBrowser/#/R-MMU-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Mus musculus 17552 R-MMU-205039 https://reactome.org/PathwayBrowser/#/R-MMU-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Mus musculus 17552 R-MMU-2255339 https://reactome.org/PathwayBrowser/#/R-MMU-2255339 RalA Exchanges GDP for GTP TAS Mus musculus 17552 R-MMU-2255341 https://reactome.org/PathwayBrowser/#/R-MMU-2255341 Rab8A/10/13/14 Exchange GDP for GTP TAS Mus musculus 17552 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 17552 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 17552 R-MMU-381727 https://reactome.org/PathwayBrowser/#/R-MMU-381727 RAP1A exchanges GDP for GTP IEA Mus musculus 17552 R-MMU-392187 https://reactome.org/PathwayBrowser/#/R-MMU-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Mus musculus 17552 R-MMU-392195 https://reactome.org/PathwayBrowser/#/R-MMU-392195 Gi activation by P2Y purinoceptor 12 IEA Mus musculus 17552 R-MMU-3928612 https://reactome.org/PathwayBrowser/#/R-MMU-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 17552 R-MMU-3928633 https://reactome.org/PathwayBrowser/#/R-MMU-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Mus musculus 17552 R-MMU-392870 https://reactome.org/PathwayBrowser/#/R-MMU-392870 Gs activation by prostacyclin receptor IEA Mus musculus 17552 R-MMU-396996 https://reactome.org/PathwayBrowser/#/R-MMU-396996 Thrombin-activated PARs binds G-protein Gq IEA Mus musculus 17552 R-MMU-416530 https://reactome.org/PathwayBrowser/#/R-MMU-416530 FFAR1:FFAR1 ligands activate Gq IEA Mus musculus 17552 R-MMU-416546 https://reactome.org/PathwayBrowser/#/R-MMU-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Mus musculus 17552 R-MMU-416588 https://reactome.org/PathwayBrowser/#/R-MMU-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Mus musculus 17552 R-MMU-418574 https://reactome.org/PathwayBrowser/#/R-MMU-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Mus musculus 17552 R-MMU-418582 https://reactome.org/PathwayBrowser/#/R-MMU-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Mus musculus 17552 R-MMU-419166 https://reactome.org/PathwayBrowser/#/R-MMU-419166 GEFs activate RhoA,B,C IEA Mus musculus 17552 R-MMU-420883 https://reactome.org/PathwayBrowser/#/R-MMU-420883 Opsins act as GEFs for G alpha-t IEA Mus musculus 17552 R-MMU-426547 https://reactome.org/PathwayBrowser/#/R-MMU-426547 Activation of Gq by Muscarinic Acetylcholine Receptor M3 TAS Mus musculus 17552 R-MMU-427858 https://reactome.org/PathwayBrowser/#/R-MMU-427858 Thrombin-activated PAR binds G-protein G12/13 TAS Mus musculus 17552 R-MMU-428749 https://reactome.org/PathwayBrowser/#/R-MMU-428749 Activated TP receptor binds G-proten Gq IEA Mus musculus 17552 R-MMU-428750 https://reactome.org/PathwayBrowser/#/R-MMU-428750 Gq activation by TP receptor IEA Mus musculus 17552 R-MMU-428909 https://reactome.org/PathwayBrowser/#/R-MMU-428909 Activated TP receptor binds G-protein G13 IEA Mus musculus 17552 R-MMU-428917 https://reactome.org/PathwayBrowser/#/R-MMU-428917 G13 activation by TP receptor IEA Mus musculus 17552 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 17552 R-MMU-5638006 https://reactome.org/PathwayBrowser/#/R-MMU-5638006 ARL3 hydrolyzes GTP IEA Mus musculus 17552 R-MMU-5638016 https://reactome.org/PathwayBrowser/#/R-MMU-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Mus musculus 17552 R-MMU-749446 https://reactome.org/PathwayBrowser/#/R-MMU-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Mus musculus 17552 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 17552 R-MMU-749453 https://reactome.org/PathwayBrowser/#/R-MMU-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Mus musculus 17552 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 17552 R-MMU-750988 https://reactome.org/PathwayBrowser/#/R-MMU-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Mus musculus 17552 R-MMU-750993 https://reactome.org/PathwayBrowser/#/R-MMU-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Mus musculus 17552 R-MMU-751001 https://reactome.org/PathwayBrowser/#/R-MMU-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Mus musculus 17552 R-MMU-751027 https://reactome.org/PathwayBrowser/#/R-MMU-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Mus musculus 17552 R-MMU-751029 https://reactome.org/PathwayBrowser/#/R-MMU-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Mus musculus 17552 R-MMU-751039 https://reactome.org/PathwayBrowser/#/R-MMU-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Mus musculus 17552 R-MMU-77081 https://reactome.org/PathwayBrowser/#/R-MMU-77081 Formation of the CE:GMP intermediate complex IEA Mus musculus 17552 R-MMU-8854329 https://reactome.org/PathwayBrowser/#/R-MMU-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Mus musculus 17552 R-MMU-8854604 https://reactome.org/PathwayBrowser/#/R-MMU-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Mus musculus 17552 R-MMU-8982012 https://reactome.org/PathwayBrowser/#/R-MMU-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Mus musculus 17552 R-MMU-8982018 https://reactome.org/PathwayBrowser/#/R-MMU-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Mus musculus 17552 R-MMU-8982026 https://reactome.org/PathwayBrowser/#/R-MMU-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Mus musculus 17552 R-MMU-8982637 https://reactome.org/PathwayBrowser/#/R-MMU-8982637 Opsins binds G alpha-t IEA Mus musculus 17552 R-MMU-9021596 https://reactome.org/PathwayBrowser/#/R-MMU-9021596 Membrane estrogen receptors bind SRC IEA Mus musculus 17552 R-MMU-9021600 https://reactome.org/PathwayBrowser/#/R-MMU-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Mus musculus 17552 R-MMU-9021601 https://reactome.org/PathwayBrowser/#/R-MMU-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Mus musculus 17552 R-NUL-1986584 https://reactome.org/PathwayBrowser/#/R-NUL-1986584 Fucosylation of Pre-Notch by POFUT1 TAS Cricetulus griseus 17552 R-NUL-428715 https://reactome.org/PathwayBrowser/#/R-NUL-428715 Activated human P2Y purinoceptor 1 binds mouse G-protein Gq TAS Homo sapiens 17552 R-NUL-804924 https://reactome.org/PathwayBrowser/#/R-NUL-804924 PKC (cow) phosphorylates G alpha z (rat) TAS Bos taurus 17552 R-NUL-8982712 https://reactome.org/PathwayBrowser/#/R-NUL-8982712 Gz(rat):PKC(cow) dissociates to give phosphorylated G alpha (z) TAS Bos taurus 17552 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 17552 R-PFA-77081 https://reactome.org/PathwayBrowser/#/R-PFA-77081 Formation of the CE:GMP intermediate complex IEA Plasmodium falciparum 17552 R-PFA-8854329 https://reactome.org/PathwayBrowser/#/R-PFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 17552 R-RNO-114558 https://reactome.org/PathwayBrowser/#/R-RNO-114558 Thrombin-activated PARs activate Gq IEA Rattus norvegicus 17552 R-RNO-170674 https://reactome.org/PathwayBrowser/#/R-RNO-170674 Dissociation of the Gi alpha:G olf complex IEA Rattus norvegicus 17552 R-RNO-170686 https://reactome.org/PathwayBrowser/#/R-RNO-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Rattus norvegicus 17552 R-RNO-205039 https://reactome.org/PathwayBrowser/#/R-RNO-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Rattus norvegicus 17552 R-RNO-2457808 https://reactome.org/PathwayBrowser/#/R-RNO-2457808 Rab8A/13/14 Exchange GDP for GTP TAS Rattus norvegicus 17552 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 17552 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 17552 R-RNO-381727 https://reactome.org/PathwayBrowser/#/R-RNO-381727 RAP1A exchanges GDP for GTP IEA Rattus norvegicus 17552 R-RNO-392195 https://reactome.org/PathwayBrowser/#/R-RNO-392195 Gi activation by P2Y purinoceptor 12 IEA Rattus norvegicus 17552 R-RNO-3928612 https://reactome.org/PathwayBrowser/#/R-RNO-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 17552 R-RNO-3928633 https://reactome.org/PathwayBrowser/#/R-RNO-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Rattus norvegicus 17552 R-RNO-416530 https://reactome.org/PathwayBrowser/#/R-RNO-416530 FFAR1:FFAR1 ligands activate Gq IEA Rattus norvegicus 17552 R-RNO-416546 https://reactome.org/PathwayBrowser/#/R-RNO-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Rattus norvegicus 17552 R-RNO-416588 https://reactome.org/PathwayBrowser/#/R-RNO-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Rattus norvegicus 17552 R-RNO-418574 https://reactome.org/PathwayBrowser/#/R-RNO-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Rattus norvegicus 17552 R-RNO-418582 https://reactome.org/PathwayBrowser/#/R-RNO-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Rattus norvegicus 17552 R-RNO-419166 https://reactome.org/PathwayBrowser/#/R-RNO-419166 GEFs activate RhoA,B,C IEA Rattus norvegicus 17552 R-RNO-420883 https://reactome.org/PathwayBrowser/#/R-RNO-420883 Opsins act as GEFs for G alpha-t IEA Rattus norvegicus 17552 R-RNO-421896 https://reactome.org/PathwayBrowser/#/R-RNO-421896 G alpha (i)1 auto-inactivates by hydrolysing GTP to GDP TAS Rattus norvegicus 17552 R-RNO-428750 https://reactome.org/PathwayBrowser/#/R-RNO-428750 Gq activation by TP receptor IEA Rattus norvegicus 17552 R-RNO-428917 https://reactome.org/PathwayBrowser/#/R-RNO-428917 G13 activation by TP receptor IEA Rattus norvegicus 17552 R-RNO-446954 https://reactome.org/PathwayBrowser/#/R-RNO-446954 Activation of G(s) by the Glucagon-like peptide-1 receptor (Glp1r, rat) TAS Rattus norvegicus 17552 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 17552 R-RNO-5638006 https://reactome.org/PathwayBrowser/#/R-RNO-5638006 ARL3 hydrolyzes GTP IEA Rattus norvegicus 17552 R-RNO-5638016 https://reactome.org/PathwayBrowser/#/R-RNO-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Rattus norvegicus 17552 R-RNO-749453 https://reactome.org/PathwayBrowser/#/R-RNO-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Rattus norvegicus 17552 R-RNO-77081 https://reactome.org/PathwayBrowser/#/R-RNO-77081 Formation of the CE:GMP intermediate complex IEA Rattus norvegicus 17552 R-RNO-8854329 https://reactome.org/PathwayBrowser/#/R-RNO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 17552 R-RNO-8854604 https://reactome.org/PathwayBrowser/#/R-RNO-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Rattus norvegicus 17552 R-RNO-8982012 https://reactome.org/PathwayBrowser/#/R-RNO-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Rattus norvegicus 17552 R-RNO-8982018 https://reactome.org/PathwayBrowser/#/R-RNO-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Rattus norvegicus 17552 R-RNO-8982026 https://reactome.org/PathwayBrowser/#/R-RNO-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Rattus norvegicus 17552 R-RNO-9021596 https://reactome.org/PathwayBrowser/#/R-RNO-9021596 Membrane estrogen receptors bind SRC IEA Rattus norvegicus 17552 R-SCE-381727 https://reactome.org/PathwayBrowser/#/R-SCE-381727 RAP1A exchanges GDP for GTP IEA Saccharomyces cerevisiae 17552 R-SCE-418574 https://reactome.org/PathwayBrowser/#/R-SCE-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Saccharomyces cerevisiae 17552 R-SCE-418582 https://reactome.org/PathwayBrowser/#/R-SCE-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Saccharomyces cerevisiae 17552 R-SCE-419166 https://reactome.org/PathwayBrowser/#/R-SCE-419166 GEFs activate RhoA,B,C IEA Saccharomyces cerevisiae 17552 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 17552 R-SCE-77081 https://reactome.org/PathwayBrowser/#/R-SCE-77081 Formation of the CE:GMP intermediate complex IEA Saccharomyces cerevisiae 17552 R-SCE-8854329 https://reactome.org/PathwayBrowser/#/R-SCE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 17552 R-SCE-8982012 https://reactome.org/PathwayBrowser/#/R-SCE-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Saccharomyces cerevisiae 17552 R-SCE-8982018 https://reactome.org/PathwayBrowser/#/R-SCE-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Saccharomyces cerevisiae 17552 R-SCE-8982026 https://reactome.org/PathwayBrowser/#/R-SCE-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Saccharomyces cerevisiae 17552 R-SPO-418574 https://reactome.org/PathwayBrowser/#/R-SPO-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Schizosaccharomyces pombe 17552 R-SPO-418582 https://reactome.org/PathwayBrowser/#/R-SPO-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Schizosaccharomyces pombe 17552 R-SPO-419166 https://reactome.org/PathwayBrowser/#/R-SPO-419166 GEFs activate RhoA,B,C IEA Schizosaccharomyces pombe 17552 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 17552 R-SPO-77081 https://reactome.org/PathwayBrowser/#/R-SPO-77081 Formation of the CE:GMP intermediate complex IEA Schizosaccharomyces pombe 17552 R-SPO-8854329 https://reactome.org/PathwayBrowser/#/R-SPO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 17552 R-SPO-8982012 https://reactome.org/PathwayBrowser/#/R-SPO-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Schizosaccharomyces pombe 17552 R-SPO-8982018 https://reactome.org/PathwayBrowser/#/R-SPO-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Schizosaccharomyces pombe 17552 R-SPO-8982026 https://reactome.org/PathwayBrowser/#/R-SPO-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Schizosaccharomyces pombe 17552 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa 17552 R-SSC-114558 https://reactome.org/PathwayBrowser/#/R-SSC-114558 Thrombin-activated PARs activate Gq IEA Sus scrofa 17552 R-SSC-170674 https://reactome.org/PathwayBrowser/#/R-SSC-170674 Dissociation of the Gi alpha:G olf complex IEA Sus scrofa 17552 R-SSC-170686 https://reactome.org/PathwayBrowser/#/R-SSC-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Sus scrofa 17552 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa 17552 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 17552 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 17552 R-SSC-381727 https://reactome.org/PathwayBrowser/#/R-SSC-381727 RAP1A exchanges GDP for GTP IEA Sus scrofa 17552 R-SSC-392187 https://reactome.org/PathwayBrowser/#/R-SSC-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Sus scrofa 17552 R-SSC-392195 https://reactome.org/PathwayBrowser/#/R-SSC-392195 Gi activation by P2Y purinoceptor 12 IEA Sus scrofa 17552 R-SSC-3928633 https://reactome.org/PathwayBrowser/#/R-SSC-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Sus scrofa 17552 R-SSC-392870 https://reactome.org/PathwayBrowser/#/R-SSC-392870 Gs activation by prostacyclin receptor IEA Sus scrofa 17552 R-SSC-396996 https://reactome.org/PathwayBrowser/#/R-SSC-396996 Thrombin-activated PARs binds G-protein Gq IEA Sus scrofa 17552 R-SSC-416546 https://reactome.org/PathwayBrowser/#/R-SSC-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Sus scrofa 17552 R-SSC-416588 https://reactome.org/PathwayBrowser/#/R-SSC-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Sus scrofa 17552 R-SSC-418574 https://reactome.org/PathwayBrowser/#/R-SSC-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa 17552 R-SSC-418582 https://reactome.org/PathwayBrowser/#/R-SSC-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa 17552 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa 17552 R-SSC-420883 https://reactome.org/PathwayBrowser/#/R-SSC-420883 Opsins act as GEFs for G alpha-t IEA Sus scrofa 17552 R-SSC-428749 https://reactome.org/PathwayBrowser/#/R-SSC-428749 Activated TP receptor binds G-proten Gq IEA Sus scrofa 17552 R-SSC-428750 https://reactome.org/PathwayBrowser/#/R-SSC-428750 Gq activation by TP receptor IEA Sus scrofa 17552 R-SSC-428909 https://reactome.org/PathwayBrowser/#/R-SSC-428909 Activated TP receptor binds G-protein G13 IEA Sus scrofa 17552 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa 17552 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 17552 R-SSC-749446 https://reactome.org/PathwayBrowser/#/R-SSC-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Sus scrofa 17552 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 17552 R-SSC-749453 https://reactome.org/PathwayBrowser/#/R-SSC-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Sus scrofa 17552 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 17552 R-SSC-750988 https://reactome.org/PathwayBrowser/#/R-SSC-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Sus scrofa 17552 R-SSC-750993 https://reactome.org/PathwayBrowser/#/R-SSC-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Sus scrofa 17552 R-SSC-751001 https://reactome.org/PathwayBrowser/#/R-SSC-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Sus scrofa 17552 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa 17552 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa 17552 R-SSC-751039 https://reactome.org/PathwayBrowser/#/R-SSC-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Sus scrofa 17552 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa 17552 R-SSC-8854329 https://reactome.org/PathwayBrowser/#/R-SSC-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 17552 R-SSC-8854604 https://reactome.org/PathwayBrowser/#/R-SSC-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Sus scrofa 17552 R-SSC-8982012 https://reactome.org/PathwayBrowser/#/R-SSC-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Sus scrofa 17552 R-SSC-8982018 https://reactome.org/PathwayBrowser/#/R-SSC-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Sus scrofa 17552 R-SSC-8982026 https://reactome.org/PathwayBrowser/#/R-SSC-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Sus scrofa 17552 R-SSC-8982637 https://reactome.org/PathwayBrowser/#/R-SSC-8982637 Opsins binds G alpha-t IEA Sus scrofa 17552 R-SSC-9021596 https://reactome.org/PathwayBrowser/#/R-SSC-9021596 Membrane estrogen receptors bind SRC IEA Sus scrofa 17552 R-SSC-9021600 https://reactome.org/PathwayBrowser/#/R-SSC-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Sus scrofa 17552 R-SSC-9021601 https://reactome.org/PathwayBrowser/#/R-SSC-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Sus scrofa 17552 R-XTR-114552 https://reactome.org/PathwayBrowser/#/R-XTR-114552 Thrombin-activated PARs activate G12/13 IEA Xenopus tropicalis 17552 R-XTR-114558 https://reactome.org/PathwayBrowser/#/R-XTR-114558 Thrombin-activated PARs activate Gq IEA Xenopus tropicalis 17552 R-XTR-170674 https://reactome.org/PathwayBrowser/#/R-XTR-170674 Dissociation of the Gi alpha:G olf complex IEA Xenopus tropicalis 17552 R-XTR-170686 https://reactome.org/PathwayBrowser/#/R-XTR-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Xenopus tropicalis 17552 R-XTR-205039 https://reactome.org/PathwayBrowser/#/R-XTR-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Xenopus tropicalis 17552 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 17552 R-XTR-381727 https://reactome.org/PathwayBrowser/#/R-XTR-381727 RAP1A exchanges GDP for GTP IEA Xenopus tropicalis 17552 R-XTR-392187 https://reactome.org/PathwayBrowser/#/R-XTR-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Xenopus tropicalis 17552 R-XTR-392195 https://reactome.org/PathwayBrowser/#/R-XTR-392195 Gi activation by P2Y purinoceptor 12 IEA Xenopus tropicalis 17552 R-XTR-3928633 https://reactome.org/PathwayBrowser/#/R-XTR-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Xenopus tropicalis 17552 R-XTR-392870 https://reactome.org/PathwayBrowser/#/R-XTR-392870 Gs activation by prostacyclin receptor IEA Xenopus tropicalis 17552 R-XTR-396996 https://reactome.org/PathwayBrowser/#/R-XTR-396996 Thrombin-activated PARs binds G-protein Gq IEA Xenopus tropicalis 17552 R-XTR-416546 https://reactome.org/PathwayBrowser/#/R-XTR-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Xenopus tropicalis 17552 R-XTR-416588 https://reactome.org/PathwayBrowser/#/R-XTR-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Xenopus tropicalis 17552 R-XTR-418574 https://reactome.org/PathwayBrowser/#/R-XTR-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Xenopus tropicalis 17552 R-XTR-418582 https://reactome.org/PathwayBrowser/#/R-XTR-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Xenopus tropicalis 17552 R-XTR-419166 https://reactome.org/PathwayBrowser/#/R-XTR-419166 GEFs activate RhoA,B,C IEA Xenopus tropicalis 17552 R-XTR-420883 https://reactome.org/PathwayBrowser/#/R-XTR-420883 Opsins act as GEFs for G alpha-t IEA Xenopus tropicalis 17552 R-XTR-428749 https://reactome.org/PathwayBrowser/#/R-XTR-428749 Activated TP receptor binds G-proten Gq IEA Xenopus tropicalis 17552 R-XTR-428750 https://reactome.org/PathwayBrowser/#/R-XTR-428750 Gq activation by TP receptor IEA Xenopus tropicalis 17552 R-XTR-428909 https://reactome.org/PathwayBrowser/#/R-XTR-428909 Activated TP receptor binds G-protein G13 IEA Xenopus tropicalis 17552 R-XTR-428917 https://reactome.org/PathwayBrowser/#/R-XTR-428917 G13 activation by TP receptor IEA Xenopus tropicalis 17552 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 17552 R-XTR-749446 https://reactome.org/PathwayBrowser/#/R-XTR-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Xenopus tropicalis 17552 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 17552 R-XTR-749453 https://reactome.org/PathwayBrowser/#/R-XTR-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Xenopus tropicalis 17552 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 17552 R-XTR-750988 https://reactome.org/PathwayBrowser/#/R-XTR-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Xenopus tropicalis 17552 R-XTR-750993 https://reactome.org/PathwayBrowser/#/R-XTR-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Xenopus tropicalis 17552 R-XTR-751001 https://reactome.org/PathwayBrowser/#/R-XTR-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Xenopus tropicalis 17552 R-XTR-751027 https://reactome.org/PathwayBrowser/#/R-XTR-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Xenopus tropicalis 17552 R-XTR-751029 https://reactome.org/PathwayBrowser/#/R-XTR-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Xenopus tropicalis 17552 R-XTR-751039 https://reactome.org/PathwayBrowser/#/R-XTR-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Xenopus tropicalis 17552 R-XTR-77081 https://reactome.org/PathwayBrowser/#/R-XTR-77081 Formation of the CE:GMP intermediate complex IEA Xenopus tropicalis 17552 R-XTR-8854329 https://reactome.org/PathwayBrowser/#/R-XTR-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 17552 R-XTR-8982012 https://reactome.org/PathwayBrowser/#/R-XTR-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Xenopus tropicalis 17552 R-XTR-8982018 https://reactome.org/PathwayBrowser/#/R-XTR-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Xenopus tropicalis 17552 R-XTR-8982026 https://reactome.org/PathwayBrowser/#/R-XTR-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Xenopus tropicalis 17552 R-XTR-8982637 https://reactome.org/PathwayBrowser/#/R-XTR-8982637 Opsins binds G alpha-t IEA Xenopus tropicalis 17552 R-XTR-9021600 https://reactome.org/PathwayBrowser/#/R-XTR-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Xenopus tropicalis 17552 R-XTR-9021601 https://reactome.org/PathwayBrowser/#/R-XTR-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Xenopus tropicalis 17553 R-BTA-1483096 https://reactome.org/PathwayBrowser/#/R-BTA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Bos taurus 17553 R-BTA-1483190 https://reactome.org/PathwayBrowser/#/R-BTA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Bos taurus 17553 R-BTA-1483222 https://reactome.org/PathwayBrowser/#/R-BTA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Bos taurus 17553 R-BTA-428681 https://reactome.org/PathwayBrowser/#/R-BTA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Bos taurus 17553 R-BTA-5696415 https://reactome.org/PathwayBrowser/#/R-BTA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Bos taurus 17553 R-CEL-1483190 https://reactome.org/PathwayBrowser/#/R-CEL-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Caenorhabditis elegans 17553 R-CEL-1483222 https://reactome.org/PathwayBrowser/#/R-CEL-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Caenorhabditis elegans 17553 R-CEL-428681 https://reactome.org/PathwayBrowser/#/R-CEL-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Caenorhabditis elegans 17553 R-CEL-5696415 https://reactome.org/PathwayBrowser/#/R-CEL-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Caenorhabditis elegans 17553 R-CFA-1483096 https://reactome.org/PathwayBrowser/#/R-CFA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Canis familiaris 17553 R-CFA-1483190 https://reactome.org/PathwayBrowser/#/R-CFA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Canis familiaris 17553 R-CFA-1483222 https://reactome.org/PathwayBrowser/#/R-CFA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Canis familiaris 17553 R-CFA-428681 https://reactome.org/PathwayBrowser/#/R-CFA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Canis familiaris 17553 R-CFA-5696415 https://reactome.org/PathwayBrowser/#/R-CFA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Canis familiaris 17553 R-DDI-1483190 https://reactome.org/PathwayBrowser/#/R-DDI-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Dictyostelium discoideum 17553 R-DDI-1483222 https://reactome.org/PathwayBrowser/#/R-DDI-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Dictyostelium discoideum 17553 R-DDI-428681 https://reactome.org/PathwayBrowser/#/R-DDI-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Dictyostelium discoideum 17553 R-DME-1483096 https://reactome.org/PathwayBrowser/#/R-DME-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Drosophila melanogaster 17553 R-DME-1483190 https://reactome.org/PathwayBrowser/#/R-DME-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Drosophila melanogaster 17553 R-DME-1483222 https://reactome.org/PathwayBrowser/#/R-DME-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Drosophila melanogaster 17553 R-DME-428681 https://reactome.org/PathwayBrowser/#/R-DME-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Drosophila melanogaster 17553 R-DME-5696415 https://reactome.org/PathwayBrowser/#/R-DME-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Drosophila melanogaster 17553 R-DRE-1483096 https://reactome.org/PathwayBrowser/#/R-DRE-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Danio rerio 17553 R-DRE-1483190 https://reactome.org/PathwayBrowser/#/R-DRE-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Danio rerio 17553 R-DRE-1483222 https://reactome.org/PathwayBrowser/#/R-DRE-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Danio rerio 17553 R-DRE-5696415 https://reactome.org/PathwayBrowser/#/R-DRE-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Danio rerio 17553 R-GGA-1483096 https://reactome.org/PathwayBrowser/#/R-GGA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Gallus gallus 17553 R-GGA-1483190 https://reactome.org/PathwayBrowser/#/R-GGA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Gallus gallus 17553 R-GGA-1483222 https://reactome.org/PathwayBrowser/#/R-GGA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Gallus gallus 17553 R-GGA-428681 https://reactome.org/PathwayBrowser/#/R-GGA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Gallus gallus 17553 R-GGA-5696415 https://reactome.org/PathwayBrowser/#/R-GGA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Gallus gallus 17553 R-HSA-1483096 https://reactome.org/PathwayBrowser/#/R-HSA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 TAS Homo sapiens 17553 R-HSA-1483190 https://reactome.org/PathwayBrowser/#/R-HSA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 TAS Homo sapiens 17553 R-HSA-1483222 https://reactome.org/PathwayBrowser/#/R-HSA-1483222 ETA is phosphorylated to PETA by CHK/ETNK TAS Homo sapiens 17553 R-HSA-428681 https://reactome.org/PathwayBrowser/#/R-HSA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates TAS Homo sapiens 17553 R-HSA-5696415 https://reactome.org/PathwayBrowser/#/R-HSA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA TAS Homo sapiens 17553 R-MMU-1483096 https://reactome.org/PathwayBrowser/#/R-MMU-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Mus musculus 17553 R-MMU-1483190 https://reactome.org/PathwayBrowser/#/R-MMU-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Mus musculus 17553 R-MMU-1483222 https://reactome.org/PathwayBrowser/#/R-MMU-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Mus musculus 17553 R-MMU-428681 https://reactome.org/PathwayBrowser/#/R-MMU-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Mus musculus 17553 R-MMU-5696415 https://reactome.org/PathwayBrowser/#/R-MMU-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Mus musculus 17553 R-PFA-1483190 https://reactome.org/PathwayBrowser/#/R-PFA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Plasmodium falciparum 17553 R-PFA-1483222 https://reactome.org/PathwayBrowser/#/R-PFA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Plasmodium falciparum 17553 R-RNO-1483096 https://reactome.org/PathwayBrowser/#/R-RNO-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Rattus norvegicus 17553 R-RNO-1483190 https://reactome.org/PathwayBrowser/#/R-RNO-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Rattus norvegicus 17553 R-RNO-1483222 https://reactome.org/PathwayBrowser/#/R-RNO-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Rattus norvegicus 17553 R-RNO-428681 https://reactome.org/PathwayBrowser/#/R-RNO-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Rattus norvegicus 17553 R-RNO-5696415 https://reactome.org/PathwayBrowser/#/R-RNO-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Rattus norvegicus 17553 R-SCE-1483190 https://reactome.org/PathwayBrowser/#/R-SCE-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Saccharomyces cerevisiae 17553 R-SCE-1483222 https://reactome.org/PathwayBrowser/#/R-SCE-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Saccharomyces cerevisiae 17553 R-SCE-428681 https://reactome.org/PathwayBrowser/#/R-SCE-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Saccharomyces cerevisiae 17553 R-SPO-1483190 https://reactome.org/PathwayBrowser/#/R-SPO-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Schizosaccharomyces pombe 17553 R-SPO-1483222 https://reactome.org/PathwayBrowser/#/R-SPO-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Schizosaccharomyces pombe 17553 R-SSC-1483096 https://reactome.org/PathwayBrowser/#/R-SSC-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Sus scrofa 17553 R-SSC-1483190 https://reactome.org/PathwayBrowser/#/R-SSC-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Sus scrofa 17553 R-SSC-1483222 https://reactome.org/PathwayBrowser/#/R-SSC-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Sus scrofa 17553 R-SSC-428681 https://reactome.org/PathwayBrowser/#/R-SSC-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Sus scrofa 17553 R-SSC-5696415 https://reactome.org/PathwayBrowser/#/R-SSC-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Sus scrofa 17553 R-XTR-1483096 https://reactome.org/PathwayBrowser/#/R-XTR-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Xenopus tropicalis 17553 R-XTR-1483190 https://reactome.org/PathwayBrowser/#/R-XTR-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Xenopus tropicalis 17553 R-XTR-1483222 https://reactome.org/PathwayBrowser/#/R-XTR-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Xenopus tropicalis 17553 R-XTR-428681 https://reactome.org/PathwayBrowser/#/R-XTR-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Xenopus tropicalis 17553 R-XTR-5696415 https://reactome.org/PathwayBrowser/#/R-XTR-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Xenopus tropicalis 17562 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 17562 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 17562 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 17562 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17562 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17562 R-BTA-109530 https://reactome.org/PathwayBrowser/#/R-BTA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Bos taurus 17562 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 17562 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 17562 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 17562 R-BTA-109903 https://reactome.org/PathwayBrowser/#/R-BTA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Bos taurus 17562 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 17562 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 17562 R-BTA-73598 https://reactome.org/PathwayBrowser/#/R-BTA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Bos taurus 17562 R-BTA-73599 https://reactome.org/PathwayBrowser/#/R-BTA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Bos taurus 17562 R-BTA-73608 https://reactome.org/PathwayBrowser/#/R-BTA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Bos taurus 17562 R-BTA-8954327 https://reactome.org/PathwayBrowser/#/R-BTA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Bos taurus 17562 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 17562 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17562 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17562 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans 17562 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 17562 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 17562 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 17562 R-CEL-109903 https://reactome.org/PathwayBrowser/#/R-CEL-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Caenorhabditis elegans 17562 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 17562 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 17562 R-CEL-73599 https://reactome.org/PathwayBrowser/#/R-CEL-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Caenorhabditis elegans 17562 R-CEL-73608 https://reactome.org/PathwayBrowser/#/R-CEL-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Caenorhabditis elegans 17562 R-CEL-8954327 https://reactome.org/PathwayBrowser/#/R-CEL-8954327 UCKL1 phosphorylates urindine, cytidine IEA Caenorhabditis elegans 17562 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 17562 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 17562 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 17562 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17562 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17562 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 17562 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 17562 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 17562 R-CFA-109903 https://reactome.org/PathwayBrowser/#/R-CFA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Canis familiaris 17562 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 17562 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 17562 R-CFA-73598 https://reactome.org/PathwayBrowser/#/R-CFA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Canis familiaris 17562 R-CFA-73599 https://reactome.org/PathwayBrowser/#/R-CFA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Canis familiaris 17562 R-CFA-73608 https://reactome.org/PathwayBrowser/#/R-CFA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Canis familiaris 17562 R-CFA-8954327 https://reactome.org/PathwayBrowser/#/R-CFA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Canis familiaris 17562 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17562 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17562 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 17562 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 17562 R-DDI-109903 https://reactome.org/PathwayBrowser/#/R-DDI-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Dictyostelium discoideum 17562 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 17562 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 17562 R-DDI-73599 https://reactome.org/PathwayBrowser/#/R-DDI-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Dictyostelium discoideum 17562 R-DDI-73608 https://reactome.org/PathwayBrowser/#/R-DDI-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Dictyostelium discoideum 17562 R-DDI-8954327 https://reactome.org/PathwayBrowser/#/R-DDI-8954327 UCKL1 phosphorylates urindine, cytidine IEA Dictyostelium discoideum 17562 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 17562 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 17562 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17562 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17562 R-DME-109530 https://reactome.org/PathwayBrowser/#/R-DME-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Drosophila melanogaster 17562 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 17562 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 17562 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 17562 R-DME-109903 https://reactome.org/PathwayBrowser/#/R-DME-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Drosophila melanogaster 17562 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 17562 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 17562 R-DME-73599 https://reactome.org/PathwayBrowser/#/R-DME-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Drosophila melanogaster 17562 R-DME-73608 https://reactome.org/PathwayBrowser/#/R-DME-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Drosophila melanogaster 17562 R-DME-8954327 https://reactome.org/PathwayBrowser/#/R-DME-8954327 UCKL1 phosphorylates urindine, cytidine IEA Drosophila melanogaster 17562 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 17562 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 17562 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 17562 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 17562 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 17562 R-DRE-109903 https://reactome.org/PathwayBrowser/#/R-DRE-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Danio rerio 17562 R-DRE-73598 https://reactome.org/PathwayBrowser/#/R-DRE-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Danio rerio 17562 R-DRE-73599 https://reactome.org/PathwayBrowser/#/R-DRE-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Danio rerio 17562 R-DRE-73608 https://reactome.org/PathwayBrowser/#/R-DRE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Danio rerio 17562 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 17562 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 17562 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 17562 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 17562 R-GGA-109903 https://reactome.org/PathwayBrowser/#/R-GGA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Gallus gallus 17562 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 17562 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 17562 R-GGA-73598 https://reactome.org/PathwayBrowser/#/R-GGA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Gallus gallus 17562 R-GGA-73599 https://reactome.org/PathwayBrowser/#/R-GGA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Gallus gallus 17562 R-GGA-73608 https://reactome.org/PathwayBrowser/#/R-GGA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Gallus gallus 17562 R-GGA-8954327 https://reactome.org/PathwayBrowser/#/R-GGA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Gallus gallus 17562 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 17562 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 17562 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 17562 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17562 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17562 R-HSA-109530 https://reactome.org/PathwayBrowser/#/R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 TAS Homo sapiens 17562 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 17562 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 17562 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 17562 R-HSA-109903 https://reactome.org/PathwayBrowser/#/R-HSA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] TAS Homo sapiens 17562 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 17562 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 17562 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 17562 R-HSA-73598 https://reactome.org/PathwayBrowser/#/R-HSA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) TAS Homo sapiens 17562 R-HSA-73599 https://reactome.org/PathwayBrowser/#/R-HSA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] TAS Homo sapiens 17562 R-HSA-73608 https://reactome.org/PathwayBrowser/#/R-HSA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) TAS Homo sapiens 17562 R-HSA-8954327 https://reactome.org/PathwayBrowser/#/R-HSA-8954327 UCKL1 phosphorylates urindine, cytidine TAS Homo sapiens 17562 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 17562 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 17562 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 17562 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17562 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17562 R-MMU-109530 https://reactome.org/PathwayBrowser/#/R-MMU-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Mus musculus 17562 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 17562 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 17562 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 17562 R-MMU-109903 https://reactome.org/PathwayBrowser/#/R-MMU-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Mus musculus 17562 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 17562 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 17562 R-MMU-73598 https://reactome.org/PathwayBrowser/#/R-MMU-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Mus musculus 17562 R-MMU-73599 https://reactome.org/PathwayBrowser/#/R-MMU-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Mus musculus 17562 R-MMU-73608 https://reactome.org/PathwayBrowser/#/R-MMU-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Mus musculus 17562 R-MMU-8954327 https://reactome.org/PathwayBrowser/#/R-MMU-8954327 UCKL1 phosphorylates urindine, cytidine IEA Mus musculus 17562 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17562 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17562 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 17562 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 17562 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 17562 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 17562 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 17562 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 17562 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 17562 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17562 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17562 R-RNO-109530 https://reactome.org/PathwayBrowser/#/R-RNO-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Rattus norvegicus 17562 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 17562 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 17562 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 17562 R-RNO-109903 https://reactome.org/PathwayBrowser/#/R-RNO-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Rattus norvegicus 17562 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 17562 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 17562 R-RNO-73598 https://reactome.org/PathwayBrowser/#/R-RNO-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Rattus norvegicus 17562 R-RNO-73599 https://reactome.org/PathwayBrowser/#/R-RNO-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Rattus norvegicus 17562 R-RNO-73608 https://reactome.org/PathwayBrowser/#/R-RNO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Rattus norvegicus 17562 R-RNO-8954327 https://reactome.org/PathwayBrowser/#/R-RNO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Rattus norvegicus 17562 R-SCE-73608 https://reactome.org/PathwayBrowser/#/R-SCE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Saccharomyces cerevisiae 17562 R-SCE-8954327 https://reactome.org/PathwayBrowser/#/R-SCE-8954327 UCKL1 phosphorylates urindine, cytidine IEA Saccharomyces cerevisiae 17562 R-SPO-73608 https://reactome.org/PathwayBrowser/#/R-SPO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Schizosaccharomyces pombe 17562 R-SPO-8954327 https://reactome.org/PathwayBrowser/#/R-SPO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Schizosaccharomyces pombe 17562 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 17562 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 17562 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 17562 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17562 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17562 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa 17562 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 17562 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 17562 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 17562 R-SSC-109903 https://reactome.org/PathwayBrowser/#/R-SSC-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Sus scrofa 17562 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 17562 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 17562 R-SSC-73599 https://reactome.org/PathwayBrowser/#/R-SSC-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Sus scrofa 17562 R-SSC-73608 https://reactome.org/PathwayBrowser/#/R-SSC-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Sus scrofa 17562 R-SSC-8954327 https://reactome.org/PathwayBrowser/#/R-SSC-8954327 UCKL1 phosphorylates urindine, cytidine IEA Sus scrofa 17562 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 17562 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 17562 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 17562 R-XTR-109530 https://reactome.org/PathwayBrowser/#/R-XTR-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Xenopus tropicalis 17562 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 17562 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 17562 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 17562 R-XTR-109903 https://reactome.org/PathwayBrowser/#/R-XTR-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Xenopus tropicalis 17562 R-XTR-73598 https://reactome.org/PathwayBrowser/#/R-XTR-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Xenopus tropicalis 17562 R-XTR-73599 https://reactome.org/PathwayBrowser/#/R-XTR-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Xenopus tropicalis 17562 R-XTR-73608 https://reactome.org/PathwayBrowser/#/R-XTR-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Xenopus tropicalis 17562 R-XTR-8954327 https://reactome.org/PathwayBrowser/#/R-XTR-8954327 UCKL1 phosphorylates urindine, cytidine IEA Xenopus tropicalis 17568 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17568 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17568 R-BTA-110218 https://reactome.org/PathwayBrowser/#/R-BTA-110218 Cleavage of uracil by TDG glycosylase IEA Bos taurus 17568 R-BTA-110221 https://reactome.org/PathwayBrowser/#/R-BTA-110221 Cleavage of uracil by SMUG1 glycosylase IEA Bos taurus 17568 R-BTA-110231 https://reactome.org/PathwayBrowser/#/R-BTA-110231 Cleavage of uracil by MBD4 glycosylase IEA Bos taurus 17568 R-BTA-73585 https://reactome.org/PathwayBrowser/#/R-BTA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Bos taurus 17568 R-BTA-74372 https://reactome.org/PathwayBrowser/#/R-BTA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Bos taurus 17568 R-BTA-74376 https://reactome.org/PathwayBrowser/#/R-BTA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Bos taurus 17568 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17568 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17568 R-CEL-73585 https://reactome.org/PathwayBrowser/#/R-CEL-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Caenorhabditis elegans 17568 R-CEL-74372 https://reactome.org/PathwayBrowser/#/R-CEL-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Caenorhabditis elegans 17568 R-CEL-74376 https://reactome.org/PathwayBrowser/#/R-CEL-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Caenorhabditis elegans 17568 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17568 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17568 R-CFA-110215 https://reactome.org/PathwayBrowser/#/R-CFA-110215 Cleavage of uracil by UNG glycosylase IEA Canis familiaris 17568 R-CFA-110218 https://reactome.org/PathwayBrowser/#/R-CFA-110218 Cleavage of uracil by TDG glycosylase IEA Canis familiaris 17568 R-CFA-110221 https://reactome.org/PathwayBrowser/#/R-CFA-110221 Cleavage of uracil by SMUG1 glycosylase IEA Canis familiaris 17568 R-CFA-110231 https://reactome.org/PathwayBrowser/#/R-CFA-110231 Cleavage of uracil by MBD4 glycosylase IEA Canis familiaris 17568 R-CFA-73585 https://reactome.org/PathwayBrowser/#/R-CFA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Canis familiaris 17568 R-CFA-74372 https://reactome.org/PathwayBrowser/#/R-CFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Canis familiaris 17568 R-CFA-74376 https://reactome.org/PathwayBrowser/#/R-CFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Canis familiaris 17568 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17568 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17568 R-DDI-110215 https://reactome.org/PathwayBrowser/#/R-DDI-110215 Cleavage of uracil by UNG glycosylase IEA Dictyostelium discoideum 17568 R-DDI-73585 https://reactome.org/PathwayBrowser/#/R-DDI-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Dictyostelium discoideum 17568 R-DDI-74372 https://reactome.org/PathwayBrowser/#/R-DDI-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Dictyostelium discoideum 17568 R-DDI-74376 https://reactome.org/PathwayBrowser/#/R-DDI-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Dictyostelium discoideum 17568 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17568 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17568 R-DME-110218 https://reactome.org/PathwayBrowser/#/R-DME-110218 Cleavage of uracil by TDG glycosylase IEA Drosophila melanogaster 17568 R-DME-110221 https://reactome.org/PathwayBrowser/#/R-DME-110221 Cleavage of uracil by SMUG1 glycosylase IEA Drosophila melanogaster 17568 R-DME-73585 https://reactome.org/PathwayBrowser/#/R-DME-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Drosophila melanogaster 17568 R-DME-74372 https://reactome.org/PathwayBrowser/#/R-DME-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Drosophila melanogaster 17568 R-DME-74376 https://reactome.org/PathwayBrowser/#/R-DME-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Drosophila melanogaster 17568 R-DRE-110215 https://reactome.org/PathwayBrowser/#/R-DRE-110215 Cleavage of uracil by UNG glycosylase IEA Danio rerio 17568 R-DRE-110218 https://reactome.org/PathwayBrowser/#/R-DRE-110218 Cleavage of uracil by TDG glycosylase IEA Danio rerio 17568 R-DRE-73585 https://reactome.org/PathwayBrowser/#/R-DRE-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Danio rerio 17568 R-DRE-74372 https://reactome.org/PathwayBrowser/#/R-DRE-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Danio rerio 17568 R-DRE-74376 https://reactome.org/PathwayBrowser/#/R-DRE-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Danio rerio 17568 R-GGA-110215 https://reactome.org/PathwayBrowser/#/R-GGA-110215 Cleavage of uracil by UNG glycosylase IEA Gallus gallus 17568 R-GGA-110218 https://reactome.org/PathwayBrowser/#/R-GGA-110218 Cleavage of uracil by TDG glycosylase IEA Gallus gallus 17568 R-GGA-110221 https://reactome.org/PathwayBrowser/#/R-GGA-110221 Cleavage of uracil by SMUG1 glycosylase IEA Gallus gallus 17568 R-GGA-110231 https://reactome.org/PathwayBrowser/#/R-GGA-110231 Cleavage of uracil by MBD4 glycosylase IEA Gallus gallus 17568 R-GGA-353271 https://reactome.org/PathwayBrowser/#/R-GGA-353271 Cleavage of uracil by Uracil-glycosylase TAS Gallus gallus 17568 R-GGA-73585 https://reactome.org/PathwayBrowser/#/R-GGA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Gallus gallus 17568 R-GGA-74372 https://reactome.org/PathwayBrowser/#/R-GGA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Gallus gallus 17568 R-GGA-74376 https://reactome.org/PathwayBrowser/#/R-GGA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Gallus gallus 17568 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17568 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17568 R-HSA-110215 https://reactome.org/PathwayBrowser/#/R-HSA-110215 Cleavage of uracil by UNG glycosylase TAS Homo sapiens 17568 R-HSA-110218 https://reactome.org/PathwayBrowser/#/R-HSA-110218 Cleavage of uracil by TDG glycosylase TAS Homo sapiens 17568 R-HSA-110221 https://reactome.org/PathwayBrowser/#/R-HSA-110221 Cleavage of uracil by SMUG1 glycosylase TAS Homo sapiens 17568 R-HSA-110231 https://reactome.org/PathwayBrowser/#/R-HSA-110231 Cleavage of uracil by MBD4 glycosylase TAS Homo sapiens 17568 R-HSA-112265 https://reactome.org/PathwayBrowser/#/R-HSA-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] TAS Homo sapiens 17568 R-HSA-112266 https://reactome.org/PathwayBrowser/#/R-HSA-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] TAS Homo sapiens 17568 R-HSA-73585 https://reactome.org/PathwayBrowser/#/R-HSA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ TAS Homo sapiens 17568 R-HSA-74372 https://reactome.org/PathwayBrowser/#/R-HSA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] TAS Homo sapiens 17568 R-HSA-74376 https://reactome.org/PathwayBrowser/#/R-HSA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) TAS Homo sapiens 17568 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17568 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17568 R-MMU-110215 https://reactome.org/PathwayBrowser/#/R-MMU-110215 Cleavage of uracil by UNG glycosylase IEA Mus musculus 17568 R-MMU-110218 https://reactome.org/PathwayBrowser/#/R-MMU-110218 Cleavage of uracil by TDG glycosylase IEA Mus musculus 17568 R-MMU-110221 https://reactome.org/PathwayBrowser/#/R-MMU-110221 Cleavage of uracil by SMUG1 glycosylase IEA Mus musculus 17568 R-MMU-110231 https://reactome.org/PathwayBrowser/#/R-MMU-110231 Cleavage of uracil by MBD4 glycosylase IEA Mus musculus 17568 R-MMU-112265 https://reactome.org/PathwayBrowser/#/R-MMU-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Mus musculus 17568 R-MMU-112266 https://reactome.org/PathwayBrowser/#/R-MMU-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Mus musculus 17568 R-MMU-73585 https://reactome.org/PathwayBrowser/#/R-MMU-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Mus musculus 17568 R-MMU-74372 https://reactome.org/PathwayBrowser/#/R-MMU-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Mus musculus 17568 R-MMU-74376 https://reactome.org/PathwayBrowser/#/R-MMU-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Mus musculus 17568 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17568 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17568 R-PFA-110215 https://reactome.org/PathwayBrowser/#/R-PFA-110215 Cleavage of uracil by UNG glycosylase IEA Plasmodium falciparum 17568 R-PFA-74372 https://reactome.org/PathwayBrowser/#/R-PFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Plasmodium falciparum 17568 R-PFA-74376 https://reactome.org/PathwayBrowser/#/R-PFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Plasmodium falciparum 17568 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17568 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17568 R-RNO-110215 https://reactome.org/PathwayBrowser/#/R-RNO-110215 Cleavage of uracil by UNG glycosylase IEA Rattus norvegicus 17568 R-RNO-110218 https://reactome.org/PathwayBrowser/#/R-RNO-110218 Cleavage of uracil by TDG glycosylase IEA Rattus norvegicus 17568 R-RNO-110221 https://reactome.org/PathwayBrowser/#/R-RNO-110221 Cleavage of uracil by SMUG1 glycosylase IEA Rattus norvegicus 17568 R-RNO-110231 https://reactome.org/PathwayBrowser/#/R-RNO-110231 Cleavage of uracil by MBD4 glycosylase IEA Rattus norvegicus 17568 R-RNO-112265 https://reactome.org/PathwayBrowser/#/R-RNO-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Rattus norvegicus 17568 R-RNO-112266 https://reactome.org/PathwayBrowser/#/R-RNO-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Rattus norvegicus 17568 R-RNO-73585 https://reactome.org/PathwayBrowser/#/R-RNO-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Rattus norvegicus 17568 R-RNO-74372 https://reactome.org/PathwayBrowser/#/R-RNO-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Rattus norvegicus 17568 R-RNO-74376 https://reactome.org/PathwayBrowser/#/R-RNO-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Rattus norvegicus 17568 R-SCE-110215 https://reactome.org/PathwayBrowser/#/R-SCE-110215 Cleavage of uracil by UNG glycosylase IEA Saccharomyces cerevisiae 17568 R-SPO-110215 https://reactome.org/PathwayBrowser/#/R-SPO-110215 Cleavage of uracil by UNG glycosylase IEA Schizosaccharomyces pombe 17568 R-SPO-110218 https://reactome.org/PathwayBrowser/#/R-SPO-110218 Cleavage of uracil by TDG glycosylase IEA Schizosaccharomyces pombe 17568 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17568 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17568 R-SSC-110215 https://reactome.org/PathwayBrowser/#/R-SSC-110215 Cleavage of uracil by UNG glycosylase IEA Sus scrofa 17568 R-SSC-110218 https://reactome.org/PathwayBrowser/#/R-SSC-110218 Cleavage of uracil by TDG glycosylase IEA Sus scrofa 17568 R-SSC-110221 https://reactome.org/PathwayBrowser/#/R-SSC-110221 Cleavage of uracil by SMUG1 glycosylase IEA Sus scrofa 17568 R-SSC-110231 https://reactome.org/PathwayBrowser/#/R-SSC-110231 Cleavage of uracil by MBD4 glycosylase IEA Sus scrofa 17568 R-SSC-73585 https://reactome.org/PathwayBrowser/#/R-SSC-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Sus scrofa 17568 R-SSC-74372 https://reactome.org/PathwayBrowser/#/R-SSC-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Sus scrofa 17568 R-SSC-74376 https://reactome.org/PathwayBrowser/#/R-SSC-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Sus scrofa 17568 R-XTR-110215 https://reactome.org/PathwayBrowser/#/R-XTR-110215 Cleavage of uracil by UNG glycosylase IEA Xenopus tropicalis 17568 R-XTR-110218 https://reactome.org/PathwayBrowser/#/R-XTR-110218 Cleavage of uracil by TDG glycosylase IEA Xenopus tropicalis 17568 R-XTR-110221 https://reactome.org/PathwayBrowser/#/R-XTR-110221 Cleavage of uracil by SMUG1 glycosylase IEA Xenopus tropicalis 17568 R-XTR-110231 https://reactome.org/PathwayBrowser/#/R-XTR-110231 Cleavage of uracil by MBD4 glycosylase IEA Xenopus tropicalis 17568 R-XTR-112265 https://reactome.org/PathwayBrowser/#/R-XTR-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Xenopus tropicalis 17568 R-XTR-112266 https://reactome.org/PathwayBrowser/#/R-XTR-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Xenopus tropicalis 17568 R-XTR-73585 https://reactome.org/PathwayBrowser/#/R-XTR-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Xenopus tropicalis 17568 R-XTR-74372 https://reactome.org/PathwayBrowser/#/R-XTR-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Xenopus tropicalis 17568 R-XTR-74376 https://reactome.org/PathwayBrowser/#/R-XTR-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Xenopus tropicalis 175763 R-BTA-191405 https://reactome.org/PathwayBrowser/#/R-BTA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Bos taurus 175763 R-BTA-2162253 https://reactome.org/PathwayBrowser/#/R-BTA-2162253 PDSS1,2 ligates FPP to IPPP IEA Bos taurus 175763 R-BTA-2995330 https://reactome.org/PathwayBrowser/#/R-BTA-2995330 COX10 transforms heme to heme O IEA Bos taurus 175763 R-BTA-4419978 https://reactome.org/PathwayBrowser/#/R-BTA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Bos taurus 175763 R-BTA-9717830 https://reactome.org/PathwayBrowser/#/R-BTA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Bos taurus 175763 R-CEL-191303 https://reactome.org/PathwayBrowser/#/R-CEL-191303 FDPS dimer transfers IPPP to GPP IEA Caenorhabditis elegans 175763 R-CEL-2995330 https://reactome.org/PathwayBrowser/#/R-CEL-2995330 COX10 transforms heme to heme O IEA Caenorhabditis elegans 175763 R-CEL-4419978 https://reactome.org/PathwayBrowser/#/R-CEL-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Caenorhabditis elegans 175763 R-CFA-191303 https://reactome.org/PathwayBrowser/#/R-CFA-191303 FDPS dimer transfers IPPP to GPP IEA Canis familiaris 175763 R-CFA-191405 https://reactome.org/PathwayBrowser/#/R-CFA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Canis familiaris 175763 R-CFA-2162253 https://reactome.org/PathwayBrowser/#/R-CFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Canis familiaris 175763 R-CFA-2995330 https://reactome.org/PathwayBrowser/#/R-CFA-2995330 COX10 transforms heme to heme O IEA Canis familiaris 175763 R-CFA-4419978 https://reactome.org/PathwayBrowser/#/R-CFA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Canis familiaris 175763 R-CFA-9717830 https://reactome.org/PathwayBrowser/#/R-CFA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Canis familiaris 175763 R-DDI-191303 https://reactome.org/PathwayBrowser/#/R-DDI-191303 FDPS dimer transfers IPPP to GPP IEA Dictyostelium discoideum 175763 R-DDI-191405 https://reactome.org/PathwayBrowser/#/R-DDI-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Dictyostelium discoideum 175763 R-DDI-2162253 https://reactome.org/PathwayBrowser/#/R-DDI-2162253 PDSS1,2 ligates FPP to IPPP IEA Dictyostelium discoideum 175763 R-DDI-2995330 https://reactome.org/PathwayBrowser/#/R-DDI-2995330 COX10 transforms heme to heme O IEA Dictyostelium discoideum 175763 R-DDI-4419978 https://reactome.org/PathwayBrowser/#/R-DDI-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Dictyostelium discoideum 175763 R-DDI-9717830 https://reactome.org/PathwayBrowser/#/R-DDI-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Dictyostelium discoideum 175763 R-DME-191303 https://reactome.org/PathwayBrowser/#/R-DME-191303 FDPS dimer transfers IPPP to GPP IEA Drosophila melanogaster 175763 R-DME-2162253 https://reactome.org/PathwayBrowser/#/R-DME-2162253 PDSS1,2 ligates FPP to IPPP IEA Drosophila melanogaster 175763 R-DME-2995330 https://reactome.org/PathwayBrowser/#/R-DME-2995330 COX10 transforms heme to heme O IEA Drosophila melanogaster 175763 R-DME-4419978 https://reactome.org/PathwayBrowser/#/R-DME-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Drosophila melanogaster 175763 R-DME-9717830 https://reactome.org/PathwayBrowser/#/R-DME-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Drosophila melanogaster 175763 R-DRE-191303 https://reactome.org/PathwayBrowser/#/R-DRE-191303 FDPS dimer transfers IPPP to GPP IEA Danio rerio 175763 R-DRE-2162253 https://reactome.org/PathwayBrowser/#/R-DRE-2162253 PDSS1,2 ligates FPP to IPPP IEA Danio rerio 175763 R-DRE-4419978 https://reactome.org/PathwayBrowser/#/R-DRE-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Danio rerio 175763 R-GGA-191303 https://reactome.org/PathwayBrowser/#/R-GGA-191303 FDPS dimer transfers IPPP to GPP IEA Gallus gallus 175763 R-GGA-191405 https://reactome.org/PathwayBrowser/#/R-GGA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Gallus gallus 175763 R-GGA-2162253 https://reactome.org/PathwayBrowser/#/R-GGA-2162253 PDSS1,2 ligates FPP to IPPP IEA Gallus gallus 175763 R-GGA-2995330 https://reactome.org/PathwayBrowser/#/R-GGA-2995330 COX10 transforms heme to heme O IEA Gallus gallus 175763 R-GGA-4419978 https://reactome.org/PathwayBrowser/#/R-GGA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Gallus gallus 175763 R-GGA-9717830 https://reactome.org/PathwayBrowser/#/R-GGA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Gallus gallus 175763 R-HSA-191303 https://reactome.org/PathwayBrowser/#/R-HSA-191303 FDPS dimer transfers IPPP to GPP TAS Homo sapiens 175763 R-HSA-191405 https://reactome.org/PathwayBrowser/#/R-HSA-191405 Two FPP molecules dimerize to form presqualene diphosphate TAS Homo sapiens 175763 R-HSA-2162253 https://reactome.org/PathwayBrowser/#/R-HSA-2162253 PDSS1,2 ligates FPP to IPPP TAS Homo sapiens 175763 R-HSA-2995330 https://reactome.org/PathwayBrowser/#/R-HSA-2995330 COX10 transforms heme to heme O TAS Homo sapiens 175763 R-HSA-4419978 https://reactome.org/PathwayBrowser/#/R-HSA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP TAS Homo sapiens 175763 R-HSA-4755545 https://reactome.org/PathwayBrowser/#/R-HSA-4755545 Defective DHDDS does not elongate E,E-FPP TAS Homo sapiens 175763 R-HSA-9717830 https://reactome.org/PathwayBrowser/#/R-HSA-9717830 GGPS1 hexamer transfers IPPP to GPP TAS Homo sapiens 175763 R-MMU-191303 https://reactome.org/PathwayBrowser/#/R-MMU-191303 FDPS dimer transfers IPPP to GPP IEA Mus musculus 175763 R-MMU-191405 https://reactome.org/PathwayBrowser/#/R-MMU-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Mus musculus 175763 R-MMU-2162253 https://reactome.org/PathwayBrowser/#/R-MMU-2162253 PDSS1,2 ligates FPP to IPPP IEA Mus musculus 175763 R-MMU-2995330 https://reactome.org/PathwayBrowser/#/R-MMU-2995330 COX10 transforms heme to heme O IEA Mus musculus 175763 R-MMU-4419978 https://reactome.org/PathwayBrowser/#/R-MMU-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Mus musculus 175763 R-MMU-9717830 https://reactome.org/PathwayBrowser/#/R-MMU-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Mus musculus 175763 R-PFA-191303 https://reactome.org/PathwayBrowser/#/R-PFA-191303 FDPS dimer transfers IPPP to GPP IEA Plasmodium falciparum 175763 R-PFA-2162253 https://reactome.org/PathwayBrowser/#/R-PFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Plasmodium falciparum 175763 R-PFA-2995330 https://reactome.org/PathwayBrowser/#/R-PFA-2995330 COX10 transforms heme to heme O IEA Plasmodium falciparum 175763 R-RNO-191303 https://reactome.org/PathwayBrowser/#/R-RNO-191303 FDPS dimer transfers IPPP to GPP IEA Rattus norvegicus 175763 R-RNO-191405 https://reactome.org/PathwayBrowser/#/R-RNO-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Rattus norvegicus 175763 R-RNO-2162253 https://reactome.org/PathwayBrowser/#/R-RNO-2162253 PDSS1,2 ligates FPP to IPPP IEA Rattus norvegicus 175763 R-RNO-2995330 https://reactome.org/PathwayBrowser/#/R-RNO-2995330 COX10 transforms heme to heme O IEA Rattus norvegicus 175763 R-RNO-4419978 https://reactome.org/PathwayBrowser/#/R-RNO-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Rattus norvegicus 175763 R-RNO-9717830 https://reactome.org/PathwayBrowser/#/R-RNO-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Rattus norvegicus 175763 R-SCE-191303 https://reactome.org/PathwayBrowser/#/R-SCE-191303 FDPS dimer transfers IPPP to GPP IEA Saccharomyces cerevisiae 175763 R-SCE-191405 https://reactome.org/PathwayBrowser/#/R-SCE-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Saccharomyces cerevisiae 175763 R-SCE-2162253 https://reactome.org/PathwayBrowser/#/R-SCE-2162253 PDSS1,2 ligates FPP to IPPP IEA Saccharomyces cerevisiae 175763 R-SCE-2995330 https://reactome.org/PathwayBrowser/#/R-SCE-2995330 COX10 transforms heme to heme O IEA Saccharomyces cerevisiae 175763 R-SCE-4419978 https://reactome.org/PathwayBrowser/#/R-SCE-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Saccharomyces cerevisiae 175763 R-SCE-9717830 https://reactome.org/PathwayBrowser/#/R-SCE-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Saccharomyces cerevisiae 175763 R-SPO-191303 https://reactome.org/PathwayBrowser/#/R-SPO-191303 FDPS dimer transfers IPPP to GPP IEA Schizosaccharomyces pombe 175763 R-SPO-191405 https://reactome.org/PathwayBrowser/#/R-SPO-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Schizosaccharomyces pombe 175763 R-SPO-2162253 https://reactome.org/PathwayBrowser/#/R-SPO-2162253 PDSS1,2 ligates FPP to IPPP IEA Schizosaccharomyces pombe 175763 R-SPO-2995330 https://reactome.org/PathwayBrowser/#/R-SPO-2995330 COX10 transforms heme to heme O IEA Schizosaccharomyces pombe 175763 R-SPO-4419978 https://reactome.org/PathwayBrowser/#/R-SPO-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Schizosaccharomyces pombe 175763 R-SSC-191303 https://reactome.org/PathwayBrowser/#/R-SSC-191303 FDPS dimer transfers IPPP to GPP IEA Sus scrofa 175763 R-SSC-191405 https://reactome.org/PathwayBrowser/#/R-SSC-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Sus scrofa 175763 R-SSC-2162253 https://reactome.org/PathwayBrowser/#/R-SSC-2162253 PDSS1,2 ligates FPP to IPPP IEA Sus scrofa 175763 R-SSC-2995330 https://reactome.org/PathwayBrowser/#/R-SSC-2995330 COX10 transforms heme to heme O IEA Sus scrofa 175763 R-SSC-4419978 https://reactome.org/PathwayBrowser/#/R-SSC-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Sus scrofa 175763 R-SSC-9717830 https://reactome.org/PathwayBrowser/#/R-SSC-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Sus scrofa 175763 R-XTR-191405 https://reactome.org/PathwayBrowser/#/R-XTR-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Xenopus tropicalis 175763 R-XTR-2162253 https://reactome.org/PathwayBrowser/#/R-XTR-2162253 PDSS1,2 ligates FPP to IPPP IEA Xenopus tropicalis 175763 R-XTR-2995330 https://reactome.org/PathwayBrowser/#/R-XTR-2995330 COX10 transforms heme to heme O IEA Xenopus tropicalis 175763 R-XTR-9717830 https://reactome.org/PathwayBrowser/#/R-XTR-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Xenopus tropicalis 17579 R-BTA-5164399 https://reactome.org/PathwayBrowser/#/R-BTA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Bos taurus 17579 R-BTA-975635 https://reactome.org/PathwayBrowser/#/R-BTA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Bos taurus 17579 R-CEL-5164399 https://reactome.org/PathwayBrowser/#/R-CEL-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Caenorhabditis elegans 17579 R-CEL-975635 https://reactome.org/PathwayBrowser/#/R-CEL-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Caenorhabditis elegans 17579 R-CFA-5164399 https://reactome.org/PathwayBrowser/#/R-CFA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Canis familiaris 17579 R-CFA-975635 https://reactome.org/PathwayBrowser/#/R-CFA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Canis familiaris 17579 R-DME-5164399 https://reactome.org/PathwayBrowser/#/R-DME-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Drosophila melanogaster 17579 R-DME-975635 https://reactome.org/PathwayBrowser/#/R-DME-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Drosophila melanogaster 17579 R-DRE-5164399 https://reactome.org/PathwayBrowser/#/R-DRE-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Danio rerio 17579 R-DRE-975635 https://reactome.org/PathwayBrowser/#/R-DRE-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Danio rerio 17579 R-GGA-5164399 https://reactome.org/PathwayBrowser/#/R-GGA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Gallus gallus 17579 R-GGA-975635 https://reactome.org/PathwayBrowser/#/R-GGA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Gallus gallus 17579 R-HSA-5164399 https://reactome.org/PathwayBrowser/#/R-HSA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION TAS Homo sapiens 17579 R-HSA-975635 https://reactome.org/PathwayBrowser/#/R-HSA-975635 BCMO1:Fe2+ cleaves betaC to atRAL TAS Homo sapiens 17579 R-MMU-5164399 https://reactome.org/PathwayBrowser/#/R-MMU-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Mus musculus 17579 R-MMU-975635 https://reactome.org/PathwayBrowser/#/R-MMU-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Mus musculus 17579 R-RNO-5164399 https://reactome.org/PathwayBrowser/#/R-RNO-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Rattus norvegicus 17579 R-RNO-975635 https://reactome.org/PathwayBrowser/#/R-RNO-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Rattus norvegicus 17579 R-SSC-5164399 https://reactome.org/PathwayBrowser/#/R-SSC-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Sus scrofa 17579 R-SSC-975635 https://reactome.org/PathwayBrowser/#/R-SSC-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Sus scrofa 17579 R-XTR-5164399 https://reactome.org/PathwayBrowser/#/R-XTR-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Xenopus tropicalis 17579 R-XTR-975635 https://reactome.org/PathwayBrowser/#/R-XTR-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Xenopus tropicalis 17580 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 17580 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 17580 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 17580 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 17580 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 17580 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 17580 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 17580 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 17580 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 17585 R-BTA-428681 https://reactome.org/PathwayBrowser/#/R-BTA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Bos taurus 17585 R-BTA-5692261 https://reactome.org/PathwayBrowser/#/R-BTA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Bos taurus 17585 R-CEL-428681 https://reactome.org/PathwayBrowser/#/R-CEL-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Caenorhabditis elegans 17585 R-CEL-5692261 https://reactome.org/PathwayBrowser/#/R-CEL-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Caenorhabditis elegans 17585 R-CFA-428681 https://reactome.org/PathwayBrowser/#/R-CFA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Canis familiaris 17585 R-CFA-5692261 https://reactome.org/PathwayBrowser/#/R-CFA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Canis familiaris 17585 R-DDI-428681 https://reactome.org/PathwayBrowser/#/R-DDI-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Dictyostelium discoideum 17585 R-DDI-5692261 https://reactome.org/PathwayBrowser/#/R-DDI-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Dictyostelium discoideum 17585 R-DME-428681 https://reactome.org/PathwayBrowser/#/R-DME-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Drosophila melanogaster 17585 R-DME-5692261 https://reactome.org/PathwayBrowser/#/R-DME-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Drosophila melanogaster 17585 R-DRE-5692261 https://reactome.org/PathwayBrowser/#/R-DRE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Danio rerio 17585 R-GGA-428681 https://reactome.org/PathwayBrowser/#/R-GGA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Gallus gallus 17585 R-GGA-5692261 https://reactome.org/PathwayBrowser/#/R-GGA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Gallus gallus 17585 R-HSA-428681 https://reactome.org/PathwayBrowser/#/R-HSA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates TAS Homo sapiens 17585 R-HSA-5692261 https://reactome.org/PathwayBrowser/#/R-HSA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM TAS Homo sapiens 17585 R-MMU-428681 https://reactome.org/PathwayBrowser/#/R-MMU-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Mus musculus 17585 R-MMU-5692261 https://reactome.org/PathwayBrowser/#/R-MMU-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Mus musculus 17585 R-RNO-428681 https://reactome.org/PathwayBrowser/#/R-RNO-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Rattus norvegicus 17585 R-RNO-5692261 https://reactome.org/PathwayBrowser/#/R-RNO-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Rattus norvegicus 17585 R-SCE-428681 https://reactome.org/PathwayBrowser/#/R-SCE-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Saccharomyces cerevisiae 17585 R-SCE-5692261 https://reactome.org/PathwayBrowser/#/R-SCE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Saccharomyces cerevisiae 17585 R-SSC-428681 https://reactome.org/PathwayBrowser/#/R-SSC-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Sus scrofa 17585 R-SSC-5692261 https://reactome.org/PathwayBrowser/#/R-SSC-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Sus scrofa 17585 R-XTR-428681 https://reactome.org/PathwayBrowser/#/R-XTR-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Xenopus tropicalis 17594 R-BTA-8936519 https://reactome.org/PathwayBrowser/#/R-BTA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Bos taurus 17594 R-CFA-8936519 https://reactome.org/PathwayBrowser/#/R-CFA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Canis familiaris 17594 R-GGA-8936519 https://reactome.org/PathwayBrowser/#/R-GGA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Gallus gallus 17594 R-HSA-8936519 https://reactome.org/PathwayBrowser/#/R-HSA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones TAS Homo sapiens 17594 R-MMU-8936519 https://reactome.org/PathwayBrowser/#/R-MMU-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Mus musculus 17594 R-RNO-8936519 https://reactome.org/PathwayBrowser/#/R-RNO-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Rattus norvegicus 17594 R-SSC-8936519 https://reactome.org/PathwayBrowser/#/R-SSC-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Sus scrofa 17594 R-XTR-8936519 https://reactome.org/PathwayBrowser/#/R-XTR-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Xenopus tropicalis 17596 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 17596 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 17596 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 17596 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17596 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17596 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 17596 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 17596 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 17596 R-BTA-109539 https://reactome.org/PathwayBrowser/#/R-BTA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Bos taurus 17596 R-BTA-112033 https://reactome.org/PathwayBrowser/#/R-BTA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Bos taurus 17596 R-BTA-2162066 https://reactome.org/PathwayBrowser/#/R-BTA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Bos taurus 17596 R-BTA-5693346 https://reactome.org/PathwayBrowser/#/R-BTA-5693346 CECRI deaminates Ade-Rib to Ino IEA Bos taurus 17596 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 17596 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 17596 R-BTA-74241 https://reactome.org/PathwayBrowser/#/R-BTA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Bos taurus 17596 R-BTA-74242 https://reactome.org/PathwayBrowser/#/R-BTA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Bos taurus 17596 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 17596 R-BTA-9754916 https://reactome.org/PathwayBrowser/#/R-BTA-9754916 NT5C2 tetramer phosphorylates RBV IEA Bos taurus 17596 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17596 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17596 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 17596 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 17596 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 17596 R-CEL-109539 https://reactome.org/PathwayBrowser/#/R-CEL-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Caenorhabditis elegans 17596 R-CEL-112033 https://reactome.org/PathwayBrowser/#/R-CEL-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Caenorhabditis elegans 17596 R-CEL-2162066 https://reactome.org/PathwayBrowser/#/R-CEL-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Caenorhabditis elegans 17596 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 17596 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 17596 R-CEL-74241 https://reactome.org/PathwayBrowser/#/R-CEL-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Caenorhabditis elegans 17596 R-CEL-74242 https://reactome.org/PathwayBrowser/#/R-CEL-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Caenorhabditis elegans 17596 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 17596 R-CEL-9754916 https://reactome.org/PathwayBrowser/#/R-CEL-9754916 NT5C2 tetramer phosphorylates RBV IEA Caenorhabditis elegans 17596 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 17596 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 17596 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 17596 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17596 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17596 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 17596 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 17596 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 17596 R-CFA-112033 https://reactome.org/PathwayBrowser/#/R-CFA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Canis familiaris 17596 R-CFA-2162066 https://reactome.org/PathwayBrowser/#/R-CFA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Canis familiaris 17596 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 17596 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 17596 R-CFA-74241 https://reactome.org/PathwayBrowser/#/R-CFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Canis familiaris 17596 R-CFA-74242 https://reactome.org/PathwayBrowser/#/R-CFA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Canis familiaris 17596 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 17596 R-CFA-9754916 https://reactome.org/PathwayBrowser/#/R-CFA-9754916 NT5C2 tetramer phosphorylates RBV IEA Canis familiaris 17596 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17596 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17596 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 17596 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 17596 R-DDI-2162066 https://reactome.org/PathwayBrowser/#/R-DDI-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Dictyostelium discoideum 17596 R-DDI-5693346 https://reactome.org/PathwayBrowser/#/R-DDI-5693346 CECRI deaminates Ade-Rib to Ino IEA Dictyostelium discoideum 17596 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 17596 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 17596 R-DDI-74241 https://reactome.org/PathwayBrowser/#/R-DDI-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Dictyostelium discoideum 17596 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 17596 R-DDI-9754916 https://reactome.org/PathwayBrowser/#/R-DDI-9754916 NT5C2 tetramer phosphorylates RBV IEA Dictyostelium discoideum 17596 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 17596 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17596 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17596 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 17596 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 17596 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 17596 R-DME-109539 https://reactome.org/PathwayBrowser/#/R-DME-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Drosophila melanogaster 17596 R-DME-112033 https://reactome.org/PathwayBrowser/#/R-DME-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Drosophila melanogaster 17596 R-DME-2162066 https://reactome.org/PathwayBrowser/#/R-DME-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Drosophila melanogaster 17596 R-DME-5693346 https://reactome.org/PathwayBrowser/#/R-DME-5693346 CECRI deaminates Ade-Rib to Ino IEA Drosophila melanogaster 17596 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 17596 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 17596 R-DME-74242 https://reactome.org/PathwayBrowser/#/R-DME-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Drosophila melanogaster 17596 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 17596 R-DME-9754916 https://reactome.org/PathwayBrowser/#/R-DME-9754916 NT5C2 tetramer phosphorylates RBV IEA Drosophila melanogaster 17596 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 17596 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 17596 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 17596 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 17596 R-DRE-112033 https://reactome.org/PathwayBrowser/#/R-DRE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Danio rerio 17596 R-DRE-5693346 https://reactome.org/PathwayBrowser/#/R-DRE-5693346 CECRI deaminates Ade-Rib to Ino IEA Danio rerio 17596 R-DRE-74241 https://reactome.org/PathwayBrowser/#/R-DRE-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Danio rerio 17596 R-DRE-74242 https://reactome.org/PathwayBrowser/#/R-DRE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Danio rerio 17596 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 17596 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 17596 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 17596 R-GGA-109539 https://reactome.org/PathwayBrowser/#/R-GGA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Gallus gallus 17596 R-GGA-2162066 https://reactome.org/PathwayBrowser/#/R-GGA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Gallus gallus 17596 R-GGA-421174 https://reactome.org/PathwayBrowser/#/R-GGA-421174 inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate IEA Gallus gallus 17596 R-GGA-421179 https://reactome.org/PathwayBrowser/#/R-GGA-421179 inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate IEA Gallus gallus 17596 R-GGA-5693346 https://reactome.org/PathwayBrowser/#/R-GGA-5693346 CECRI deaminates Ade-Rib to Ino IEA Gallus gallus 17596 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 17596 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 17596 R-GGA-74241 https://reactome.org/PathwayBrowser/#/R-GGA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Gallus gallus 17596 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 17596 R-GGA-9754916 https://reactome.org/PathwayBrowser/#/R-GGA-9754916 NT5C2 tetramer phosphorylates RBV IEA Gallus gallus 17596 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 17596 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 17596 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 17596 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17596 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17596 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 17596 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 17596 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 17596 R-HSA-109539 https://reactome.org/PathwayBrowser/#/R-HSA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 TAS Homo sapiens 17596 R-HSA-112033 https://reactome.org/PathwayBrowser/#/R-HSA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine TAS Homo sapiens 17596 R-HSA-2162066 https://reactome.org/PathwayBrowser/#/R-HSA-2162066 carbovir + IMP => carbovir monophosphate + inosine TAS Homo sapiens 17596 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 17596 R-HSA-5693346 https://reactome.org/PathwayBrowser/#/R-HSA-5693346 CECRI deaminates Ade-Rib to Ino TAS Homo sapiens 17596 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 17596 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 17596 R-HSA-74241 https://reactome.org/PathwayBrowser/#/R-HSA-74241 ADA catalyzes the deamination of (deoxy)adenosine TAS Homo sapiens 17596 R-HSA-74242 https://reactome.org/PathwayBrowser/#/R-HSA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 17596 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 17596 R-HSA-9735775 https://reactome.org/PathwayBrowser/#/R-HSA-9735775 Defective PNP does not convert (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 17596 R-HSA-9754916 https://reactome.org/PathwayBrowser/#/R-HSA-9754916 NT5C2 tetramer phosphorylates RBV TAS Homo sapiens 17596 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 17596 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 17596 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 17596 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17596 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17596 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 17596 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 17596 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 17596 R-MMU-109539 https://reactome.org/PathwayBrowser/#/R-MMU-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Mus musculus 17596 R-MMU-112033 https://reactome.org/PathwayBrowser/#/R-MMU-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Mus musculus 17596 R-MMU-2162066 https://reactome.org/PathwayBrowser/#/R-MMU-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Mus musculus 17596 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 17596 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 17596 R-MMU-74241 https://reactome.org/PathwayBrowser/#/R-MMU-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Mus musculus 17596 R-MMU-74242 https://reactome.org/PathwayBrowser/#/R-MMU-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Mus musculus 17596 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 17596 R-MMU-9754916 https://reactome.org/PathwayBrowser/#/R-MMU-9754916 NT5C2 tetramer phosphorylates RBV IEA Mus musculus 17596 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17596 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17596 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 17596 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 17596 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 17596 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 17596 R-PFA-74241 https://reactome.org/PathwayBrowser/#/R-PFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Plasmodium falciparum 17596 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 17596 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 17596 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 17596 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17596 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17596 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 17596 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 17596 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 17596 R-RNO-109539 https://reactome.org/PathwayBrowser/#/R-RNO-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Rattus norvegicus 17596 R-RNO-112033 https://reactome.org/PathwayBrowser/#/R-RNO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Rattus norvegicus 17596 R-RNO-2162066 https://reactome.org/PathwayBrowser/#/R-RNO-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Rattus norvegicus 17596 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 17596 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 17596 R-RNO-74241 https://reactome.org/PathwayBrowser/#/R-RNO-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Rattus norvegicus 17596 R-RNO-74242 https://reactome.org/PathwayBrowser/#/R-RNO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Rattus norvegicus 17596 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 17596 R-RNO-9754916 https://reactome.org/PathwayBrowser/#/R-RNO-9754916 NT5C2 tetramer phosphorylates RBV IEA Rattus norvegicus 17596 R-SCE-112033 https://reactome.org/PathwayBrowser/#/R-SCE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Saccharomyces cerevisiae 17596 R-SCE-74242 https://reactome.org/PathwayBrowser/#/R-SCE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Saccharomyces cerevisiae 17596 R-SPO-112033 https://reactome.org/PathwayBrowser/#/R-SPO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Schizosaccharomyces pombe 17596 R-SPO-74242 https://reactome.org/PathwayBrowser/#/R-SPO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Schizosaccharomyces pombe 17596 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 17596 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 17596 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 17596 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17596 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17596 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 17596 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 17596 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 17596 R-SSC-109539 https://reactome.org/PathwayBrowser/#/R-SSC-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Sus scrofa 17596 R-SSC-112033 https://reactome.org/PathwayBrowser/#/R-SSC-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Sus scrofa 17596 R-SSC-2162066 https://reactome.org/PathwayBrowser/#/R-SSC-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Sus scrofa 17596 R-SSC-5693346 https://reactome.org/PathwayBrowser/#/R-SSC-5693346 CECRI deaminates Ade-Rib to Ino IEA Sus scrofa 17596 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 17596 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 17596 R-SSC-74241 https://reactome.org/PathwayBrowser/#/R-SSC-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Sus scrofa 17596 R-SSC-74242 https://reactome.org/PathwayBrowser/#/R-SSC-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Sus scrofa 17596 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 17596 R-SSC-9754916 https://reactome.org/PathwayBrowser/#/R-SSC-9754916 NT5C2 tetramer phosphorylates RBV IEA Sus scrofa 17596 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 17596 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 17596 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 17596 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 17596 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 17596 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 17596 R-XTR-109539 https://reactome.org/PathwayBrowser/#/R-XTR-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Xenopus tropicalis 17596 R-XTR-112033 https://reactome.org/PathwayBrowser/#/R-XTR-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Xenopus tropicalis 17596 R-XTR-2162066 https://reactome.org/PathwayBrowser/#/R-XTR-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Xenopus tropicalis 17596 R-XTR-5693346 https://reactome.org/PathwayBrowser/#/R-XTR-5693346 CECRI deaminates Ade-Rib to Ino IEA Xenopus tropicalis 17596 R-XTR-74241 https://reactome.org/PathwayBrowser/#/R-XTR-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Xenopus tropicalis 17596 R-XTR-74242 https://reactome.org/PathwayBrowser/#/R-XTR-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Xenopus tropicalis 17596 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 17596 R-XTR-9754916 https://reactome.org/PathwayBrowser/#/R-XTR-9754916 NT5C2 tetramer phosphorylates RBV IEA Xenopus tropicalis 17600 R-BTA-428681 https://reactome.org/PathwayBrowser/#/R-BTA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Bos taurus 17600 R-BTA-5696080 https://reactome.org/PathwayBrowser/#/R-BTA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Bos taurus 17600 R-BTA-6808464 https://reactome.org/PathwayBrowser/#/R-BTA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Bos taurus 17600 R-CEL-428681 https://reactome.org/PathwayBrowser/#/R-CEL-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Caenorhabditis elegans 17600 R-CEL-5696080 https://reactome.org/PathwayBrowser/#/R-CEL-5696080 ALDH3B1 oxidises HXAL to PALM IEA Caenorhabditis elegans 17600 R-CEL-6808464 https://reactome.org/PathwayBrowser/#/R-CEL-6808464 ALDH3B2 oxidises HXAL to PALM IEA Caenorhabditis elegans 17600 R-CFA-428681 https://reactome.org/PathwayBrowser/#/R-CFA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Canis familiaris 17600 R-CFA-5696080 https://reactome.org/PathwayBrowser/#/R-CFA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Canis familiaris 17600 R-CFA-6808464 https://reactome.org/PathwayBrowser/#/R-CFA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Canis familiaris 17600 R-DDI-428681 https://reactome.org/PathwayBrowser/#/R-DDI-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Dictyostelium discoideum 17600 R-DDI-5696080 https://reactome.org/PathwayBrowser/#/R-DDI-5696080 ALDH3B1 oxidises HXAL to PALM IEA Dictyostelium discoideum 17600 R-DDI-6808464 https://reactome.org/PathwayBrowser/#/R-DDI-6808464 ALDH3B2 oxidises HXAL to PALM IEA Dictyostelium discoideum 17600 R-DME-428681 https://reactome.org/PathwayBrowser/#/R-DME-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Drosophila melanogaster 17600 R-DME-5696080 https://reactome.org/PathwayBrowser/#/R-DME-5696080 ALDH3B1 oxidises HXAL to PALM IEA Drosophila melanogaster 17600 R-DME-6808464 https://reactome.org/PathwayBrowser/#/R-DME-6808464 ALDH3B2 oxidises HXAL to PALM IEA Drosophila melanogaster 17600 R-DRE-5696080 https://reactome.org/PathwayBrowser/#/R-DRE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Danio rerio 17600 R-DRE-6808464 https://reactome.org/PathwayBrowser/#/R-DRE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Danio rerio 17600 R-GGA-428681 https://reactome.org/PathwayBrowser/#/R-GGA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Gallus gallus 17600 R-GGA-5696080 https://reactome.org/PathwayBrowser/#/R-GGA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Gallus gallus 17600 R-GGA-6808464 https://reactome.org/PathwayBrowser/#/R-GGA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Gallus gallus 17600 R-HSA-428681 https://reactome.org/PathwayBrowser/#/R-HSA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates TAS Homo sapiens 17600 R-HSA-5696080 https://reactome.org/PathwayBrowser/#/R-HSA-5696080 ALDH3B1 oxidises HXAL to PALM TAS Homo sapiens 17600 R-HSA-6808464 https://reactome.org/PathwayBrowser/#/R-HSA-6808464 ALDH3B2 oxidises HXAL to PALM TAS Homo sapiens 17600 R-MMU-428681 https://reactome.org/PathwayBrowser/#/R-MMU-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Mus musculus 17600 R-MMU-5696080 https://reactome.org/PathwayBrowser/#/R-MMU-5696080 ALDH3B1 oxidises HXAL to PALM IEA Mus musculus 17600 R-MMU-6808464 https://reactome.org/PathwayBrowser/#/R-MMU-6808464 ALDH3B2 oxidises HXAL to PALM IEA Mus musculus 17600 R-RNO-428681 https://reactome.org/PathwayBrowser/#/R-RNO-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Rattus norvegicus 17600 R-RNO-5696080 https://reactome.org/PathwayBrowser/#/R-RNO-5696080 ALDH3B1 oxidises HXAL to PALM IEA Rattus norvegicus 17600 R-RNO-6808464 https://reactome.org/PathwayBrowser/#/R-RNO-6808464 ALDH3B2 oxidises HXAL to PALM IEA Rattus norvegicus 17600 R-SCE-428681 https://reactome.org/PathwayBrowser/#/R-SCE-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Saccharomyces cerevisiae 17600 R-SCE-5696080 https://reactome.org/PathwayBrowser/#/R-SCE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 17600 R-SCE-6808464 https://reactome.org/PathwayBrowser/#/R-SCE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 17600 R-SSC-428681 https://reactome.org/PathwayBrowser/#/R-SSC-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Sus scrofa 17600 R-SSC-5696080 https://reactome.org/PathwayBrowser/#/R-SSC-5696080 ALDH3B1 oxidises HXAL to PALM IEA Sus scrofa 17600 R-SSC-6808464 https://reactome.org/PathwayBrowser/#/R-SSC-6808464 ALDH3B2 oxidises HXAL to PALM IEA Sus scrofa 17600 R-XTR-428681 https://reactome.org/PathwayBrowser/#/R-XTR-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Xenopus tropicalis 17600 R-XTR-5696080 https://reactome.org/PathwayBrowser/#/R-XTR-5696080 ALDH3B1 oxidises HXAL to PALM IEA Xenopus tropicalis 17600 R-XTR-6808464 https://reactome.org/PathwayBrowser/#/R-XTR-6808464 ALDH3B2 oxidises HXAL to PALM IEA Xenopus tropicalis 17606 R-BTA-209815 https://reactome.org/PathwayBrowser/#/R-BTA-209815 Tyrosine is monoiodinated IEA Bos taurus 17606 R-BTA-350901 https://reactome.org/PathwayBrowser/#/R-BTA-350901 Iodide is organified IEA Bos taurus 17606 R-CEL-209815 https://reactome.org/PathwayBrowser/#/R-CEL-209815 Tyrosine is monoiodinated IEA Caenorhabditis elegans 17606 R-CEL-350901 https://reactome.org/PathwayBrowser/#/R-CEL-350901 Iodide is organified IEA Caenorhabditis elegans 17606 R-CFA-209815 https://reactome.org/PathwayBrowser/#/R-CFA-209815 Tyrosine is monoiodinated IEA Canis familiaris 17606 R-CFA-350901 https://reactome.org/PathwayBrowser/#/R-CFA-350901 Iodide is organified IEA Canis familiaris 17606 R-DDI-209815 https://reactome.org/PathwayBrowser/#/R-DDI-209815 Tyrosine is monoiodinated IEA Dictyostelium discoideum 17606 R-DDI-350901 https://reactome.org/PathwayBrowser/#/R-DDI-350901 Iodide is organified IEA Dictyostelium discoideum 17606 R-DME-209815 https://reactome.org/PathwayBrowser/#/R-DME-209815 Tyrosine is monoiodinated IEA Drosophila melanogaster 17606 R-DME-350901 https://reactome.org/PathwayBrowser/#/R-DME-350901 Iodide is organified IEA Drosophila melanogaster 17606 R-GGA-209815 https://reactome.org/PathwayBrowser/#/R-GGA-209815 Tyrosine is monoiodinated IEA Gallus gallus 17606 R-GGA-350901 https://reactome.org/PathwayBrowser/#/R-GGA-350901 Iodide is organified IEA Gallus gallus 17606 R-HSA-209815 https://reactome.org/PathwayBrowser/#/R-HSA-209815 Tyrosine is monoiodinated TAS Homo sapiens 17606 R-HSA-350901 https://reactome.org/PathwayBrowser/#/R-HSA-350901 Iodide is organified TAS Homo sapiens 17606 R-MMU-209815 https://reactome.org/PathwayBrowser/#/R-MMU-209815 Tyrosine is monoiodinated IEA Mus musculus 17606 R-MMU-350901 https://reactome.org/PathwayBrowser/#/R-MMU-350901 Iodide is organified IEA Mus musculus 17606 R-RNO-209815 https://reactome.org/PathwayBrowser/#/R-RNO-209815 Tyrosine is monoiodinated IEA Rattus norvegicus 17606 R-RNO-350901 https://reactome.org/PathwayBrowser/#/R-RNO-350901 Iodide is organified IEA Rattus norvegicus 17606 R-SSC-209815 https://reactome.org/PathwayBrowser/#/R-SSC-209815 Tyrosine is monoiodinated IEA Sus scrofa 17606 R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa 17612 R-BTA-379382 https://reactome.org/PathwayBrowser/#/R-BTA-379382 MAOA:FAD deaminates DA to DOPAC IEA Bos taurus 17612 R-BTA-379464 https://reactome.org/PathwayBrowser/#/R-BTA-379464 COMT transfers Met to DOPAC to form HVA IEA Bos taurus 17612 R-CFA-379382 https://reactome.org/PathwayBrowser/#/R-CFA-379382 MAOA:FAD deaminates DA to DOPAC IEA Canis familiaris 17612 R-CFA-379464 https://reactome.org/PathwayBrowser/#/R-CFA-379464 COMT transfers Met to DOPAC to form HVA IEA Canis familiaris 17612 R-DDI-379382 https://reactome.org/PathwayBrowser/#/R-DDI-379382 MAOA:FAD deaminates DA to DOPAC IEA Dictyostelium discoideum 17612 R-DRE-379464 https://reactome.org/PathwayBrowser/#/R-DRE-379464 COMT transfers Met to DOPAC to form HVA IEA Danio rerio 17612 R-GGA-379382 https://reactome.org/PathwayBrowser/#/R-GGA-379382 MAOA:FAD deaminates DA to DOPAC IEA Gallus gallus 17612 R-GGA-379464 https://reactome.org/PathwayBrowser/#/R-GGA-379464 COMT transfers Met to DOPAC to form HVA IEA Gallus gallus 17612 R-HSA-379382 https://reactome.org/PathwayBrowser/#/R-HSA-379382 MAOA:FAD deaminates DA to DOPAC TAS Homo sapiens 17612 R-HSA-379464 https://reactome.org/PathwayBrowser/#/R-HSA-379464 COMT transfers Met to DOPAC to form HVA TAS Homo sapiens 17612 R-MMU-379382 https://reactome.org/PathwayBrowser/#/R-MMU-379382 MAOA:FAD deaminates DA to DOPAC IEA Mus musculus 17612 R-MMU-379464 https://reactome.org/PathwayBrowser/#/R-MMU-379464 COMT transfers Met to DOPAC to form HVA IEA Mus musculus 17612 R-RNO-379382 https://reactome.org/PathwayBrowser/#/R-RNO-379382 MAOA:FAD deaminates DA to DOPAC IEA Rattus norvegicus 17612 R-RNO-379464 https://reactome.org/PathwayBrowser/#/R-RNO-379464 COMT transfers Met to DOPAC to form HVA IEA Rattus norvegicus 17612 R-SPO-379464 https://reactome.org/PathwayBrowser/#/R-SPO-379464 COMT transfers Met to DOPAC to form HVA IEA Schizosaccharomyces pombe 17612 R-SSC-379382 https://reactome.org/PathwayBrowser/#/R-SSC-379382 MAOA:FAD deaminates DA to DOPAC IEA Sus scrofa 17612 R-SSC-379464 https://reactome.org/PathwayBrowser/#/R-SSC-379464 COMT transfers Met to DOPAC to form HVA IEA Sus scrofa 17612 R-XTR-379464 https://reactome.org/PathwayBrowser/#/R-XTR-379464 COMT transfers Met to DOPAC to form HVA IEA Xenopus tropicalis 17616 R-BTA-2187332 https://reactome.org/PathwayBrowser/#/R-BTA-2187332 Cytosolic CMs translocate to extracellular region IEA Bos taurus 17616 R-BTA-2395764 https://reactome.org/PathwayBrowser/#/R-BTA-2395764 atREs binds to nascent CM IEA Bos taurus 17616 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 17616 R-BTA-2395784 https://reactome.org/PathwayBrowser/#/R-BTA-2395784 Nascent CMs transform into mature CMs IEA Bos taurus 17616 R-BTA-2404131 https://reactome.org/PathwayBrowser/#/R-BTA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Bos taurus 17616 R-BTA-2404137 https://reactome.org/PathwayBrowser/#/R-BTA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 17616 R-BTA-2423785 https://reactome.org/PathwayBrowser/#/R-BTA-2423785 CR:atREs binds apoE and HSPG IEA Bos taurus 17616 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 17616 R-BTA-2453855 https://reactome.org/PathwayBrowser/#/R-BTA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 17616 R-BTA-8848355 https://reactome.org/PathwayBrowser/#/R-BTA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Bos taurus 17616 R-BTA-8848585 https://reactome.org/PathwayBrowser/#/R-BTA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Bos taurus 17616 R-BTA-975593 https://reactome.org/PathwayBrowser/#/R-BTA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Bos taurus 17616 R-BTA-975594 https://reactome.org/PathwayBrowser/#/R-BTA-975594 PLB1 hydrolyses RPALM to atROL IEA Bos taurus 17616 R-BTA-975608 https://reactome.org/PathwayBrowser/#/R-BTA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Bos taurus 17616 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 17616 R-CEL-8848585 https://reactome.org/PathwayBrowser/#/R-CEL-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Caenorhabditis elegans 17616 R-CEL-975594 https://reactome.org/PathwayBrowser/#/R-CEL-975594 PLB1 hydrolyses RPALM to atROL IEA Caenorhabditis elegans 17616 R-CFA-2187332 https://reactome.org/PathwayBrowser/#/R-CFA-2187332 Cytosolic CMs translocate to extracellular region IEA Canis familiaris 17616 R-CFA-2395764 https://reactome.org/PathwayBrowser/#/R-CFA-2395764 atREs binds to nascent CM IEA Canis familiaris 17616 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 17616 R-CFA-2395784 https://reactome.org/PathwayBrowser/#/R-CFA-2395784 Nascent CMs transform into mature CMs IEA Canis familiaris 17616 R-CFA-2404131 https://reactome.org/PathwayBrowser/#/R-CFA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Canis familiaris 17616 R-CFA-2404137 https://reactome.org/PathwayBrowser/#/R-CFA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 17616 R-CFA-2423785 https://reactome.org/PathwayBrowser/#/R-CFA-2423785 CR:atREs binds apoE and HSPG IEA Canis familiaris 17616 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 17616 R-CFA-2453855 https://reactome.org/PathwayBrowser/#/R-CFA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 17616 R-CFA-8848355 https://reactome.org/PathwayBrowser/#/R-CFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Canis familiaris 17616 R-CFA-8848585 https://reactome.org/PathwayBrowser/#/R-CFA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Canis familiaris 17616 R-CFA-975594 https://reactome.org/PathwayBrowser/#/R-CFA-975594 PLB1 hydrolyses RPALM to atROL IEA Canis familiaris 17616 R-CFA-975608 https://reactome.org/PathwayBrowser/#/R-CFA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Canis familiaris 17616 R-DDI-8848585 https://reactome.org/PathwayBrowser/#/R-DDI-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Dictyostelium discoideum 17616 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 17616 R-DME-8848585 https://reactome.org/PathwayBrowser/#/R-DME-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Drosophila melanogaster 17616 R-DME-975594 https://reactome.org/PathwayBrowser/#/R-DME-975594 PLB1 hydrolyses RPALM to atROL IEA Drosophila melanogaster 17616 R-DRE-2404137 https://reactome.org/PathwayBrowser/#/R-DRE-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 17616 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 17616 R-DRE-2453855 https://reactome.org/PathwayBrowser/#/R-DRE-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 17616 R-DRE-8848585 https://reactome.org/PathwayBrowser/#/R-DRE-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Danio rerio 17616 R-DRE-975608 https://reactome.org/PathwayBrowser/#/R-DRE-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Danio rerio 17616 R-GGA-2187332 https://reactome.org/PathwayBrowser/#/R-GGA-2187332 Cytosolic CMs translocate to extracellular region IEA Gallus gallus 17616 R-GGA-2395764 https://reactome.org/PathwayBrowser/#/R-GGA-2395764 atREs binds to nascent CM IEA Gallus gallus 17616 R-GGA-2404137 https://reactome.org/PathwayBrowser/#/R-GGA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 17616 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 17616 R-GGA-2453855 https://reactome.org/PathwayBrowser/#/R-GGA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 17616 R-GGA-8848355 https://reactome.org/PathwayBrowser/#/R-GGA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Gallus gallus 17616 R-GGA-8848585 https://reactome.org/PathwayBrowser/#/R-GGA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Gallus gallus 17616 R-GGA-975593 https://reactome.org/PathwayBrowser/#/R-GGA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Gallus gallus 17616 R-GGA-975594 https://reactome.org/PathwayBrowser/#/R-GGA-975594 PLB1 hydrolyses RPALM to atROL IEA Gallus gallus 17616 R-GGA-975608 https://reactome.org/PathwayBrowser/#/R-GGA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Gallus gallus 17616 R-HSA-2187332 https://reactome.org/PathwayBrowser/#/R-HSA-2187332 Cytosolic CMs translocate to extracellular region TAS Homo sapiens 17616 R-HSA-2395764 https://reactome.org/PathwayBrowser/#/R-HSA-2395764 atREs binds to nascent CM TAS Homo sapiens 17616 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 17616 R-HSA-2395784 https://reactome.org/PathwayBrowser/#/R-HSA-2395784 Nascent CMs transform into mature CMs TAS Homo sapiens 17616 R-HSA-2404131 https://reactome.org/PathwayBrowser/#/R-HSA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol TAS Homo sapiens 17616 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 17616 R-HSA-2404137 https://reactome.org/PathwayBrowser/#/R-HSA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 17616 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 17616 R-HSA-2423785 https://reactome.org/PathwayBrowser/#/R-HSA-2423785 CR:atREs binds apoE and HSPG TAS Homo sapiens 17616 R-HSA-2424254 https://reactome.org/PathwayBrowser/#/R-HSA-2424254 LDLR transports extracellular CR:atREs to cytosol IEA Homo sapiens 17616 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 17616 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 17616 R-HSA-2453855 https://reactome.org/PathwayBrowser/#/R-HSA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 17616 R-HSA-8848355 https://reactome.org/PathwayBrowser/#/R-HSA-8848355 PNPLA4 hydrolyzes retinyl palmitate TAS Homo sapiens 17616 R-HSA-8848585 https://reactome.org/PathwayBrowser/#/R-HSA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM TAS Homo sapiens 17616 R-HSA-975593 https://reactome.org/PathwayBrowser/#/R-HSA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM TAS Homo sapiens 17616 R-HSA-975594 https://reactome.org/PathwayBrowser/#/R-HSA-975594 PLB1 hydrolyses RPALM to atROL TAS Homo sapiens 17616 R-HSA-975608 https://reactome.org/PathwayBrowser/#/R-HSA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs TAS Homo sapiens 17616 R-MMU-2187332 https://reactome.org/PathwayBrowser/#/R-MMU-2187332 Cytosolic CMs translocate to extracellular region IEA Mus musculus 17616 R-MMU-2395764 https://reactome.org/PathwayBrowser/#/R-MMU-2395764 atREs binds to nascent CM IEA Mus musculus 17616 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 17616 R-MMU-2395784 https://reactome.org/PathwayBrowser/#/R-MMU-2395784 Nascent CMs transform into mature CMs IEA Mus musculus 17616 R-MMU-2404131 https://reactome.org/PathwayBrowser/#/R-MMU-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Mus musculus 17616 R-MMU-2404137 https://reactome.org/PathwayBrowser/#/R-MMU-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 17616 R-MMU-2423785 https://reactome.org/PathwayBrowser/#/R-MMU-2423785 CR:atREs binds apoE and HSPG IEA Mus musculus 17616 R-MMU-2425403 https://reactome.org/PathwayBrowser/#/R-MMU-2425403 Extracellular CR:atREs are transported to cytosol by Ldlr TAS Mus musculus 17616 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 17616 R-MMU-2453855 https://reactome.org/PathwayBrowser/#/R-MMU-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 17616 R-MMU-8848585 https://reactome.org/PathwayBrowser/#/R-MMU-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Mus musculus 17616 R-MMU-975593 https://reactome.org/PathwayBrowser/#/R-MMU-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Mus musculus 17616 R-MMU-975594 https://reactome.org/PathwayBrowser/#/R-MMU-975594 PLB1 hydrolyses RPALM to atROL IEA Mus musculus 17616 R-MMU-975608 https://reactome.org/PathwayBrowser/#/R-MMU-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Mus musculus 17616 R-PFA-8848355 https://reactome.org/PathwayBrowser/#/R-PFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Plasmodium falciparum 17616 R-RNO-2187332 https://reactome.org/PathwayBrowser/#/R-RNO-2187332 Cytosolic CMs translocate to extracellular region IEA Rattus norvegicus 17616 R-RNO-2395764 https://reactome.org/PathwayBrowser/#/R-RNO-2395764 atREs binds to nascent CM IEA Rattus norvegicus 17616 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 17616 R-RNO-2395784 https://reactome.org/PathwayBrowser/#/R-RNO-2395784 Nascent CMs transform into mature CMs IEA Rattus norvegicus 17616 R-RNO-2404131 https://reactome.org/PathwayBrowser/#/R-RNO-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Rattus norvegicus 17616 R-RNO-2404137 https://reactome.org/PathwayBrowser/#/R-RNO-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 17616 R-RNO-2423785 https://reactome.org/PathwayBrowser/#/R-RNO-2423785 CR:atREs binds apoE and HSPG IEA Rattus norvegicus 17616 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 17616 R-RNO-2453855 https://reactome.org/PathwayBrowser/#/R-RNO-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 17616 R-RNO-8848355 https://reactome.org/PathwayBrowser/#/R-RNO-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Rattus norvegicus 17616 R-RNO-8848585 https://reactome.org/PathwayBrowser/#/R-RNO-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Rattus norvegicus 17616 R-RNO-975593 https://reactome.org/PathwayBrowser/#/R-RNO-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Rattus norvegicus 17616 R-RNO-975594 https://reactome.org/PathwayBrowser/#/R-RNO-975594 PLB1 hydrolyses RPALM to atROL IEA Rattus norvegicus 17616 R-RNO-975608 https://reactome.org/PathwayBrowser/#/R-RNO-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Rattus norvegicus 17616 R-SCE-8848585 https://reactome.org/PathwayBrowser/#/R-SCE-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Saccharomyces cerevisiae 17616 R-SPO-8848585 https://reactome.org/PathwayBrowser/#/R-SPO-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Schizosaccharomyces pombe 17616 R-SSC-2187332 https://reactome.org/PathwayBrowser/#/R-SSC-2187332 Cytosolic CMs translocate to extracellular region IEA Sus scrofa 17616 R-SSC-2395764 https://reactome.org/PathwayBrowser/#/R-SSC-2395764 atREs binds to nascent CM IEA Sus scrofa 17616 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 17616 R-SSC-2395784 https://reactome.org/PathwayBrowser/#/R-SSC-2395784 Nascent CMs transform into mature CMs IEA Sus scrofa 17616 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa 17616 R-SSC-2404137 https://reactome.org/PathwayBrowser/#/R-SSC-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 17616 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa 17616 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 17616 R-SSC-2453855 https://reactome.org/PathwayBrowser/#/R-SSC-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 17616 R-SSC-8848355 https://reactome.org/PathwayBrowser/#/R-SSC-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Sus scrofa 17616 R-SSC-8848585 https://reactome.org/PathwayBrowser/#/R-SSC-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Sus scrofa 17616 R-SSC-975593 https://reactome.org/PathwayBrowser/#/R-SSC-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Sus scrofa 17616 R-SSC-975594 https://reactome.org/PathwayBrowser/#/R-SSC-975594 PLB1 hydrolyses RPALM to atROL IEA Sus scrofa 17616 R-SSC-975608 https://reactome.org/PathwayBrowser/#/R-SSC-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Sus scrofa 17616 R-XTR-2404137 https://reactome.org/PathwayBrowser/#/R-XTR-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 17616 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 17616 R-XTR-2453855 https://reactome.org/PathwayBrowser/#/R-XTR-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 17616 R-XTR-8848355 https://reactome.org/PathwayBrowser/#/R-XTR-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Xenopus tropicalis 17616 R-XTR-8848585 https://reactome.org/PathwayBrowser/#/R-XTR-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Xenopus tropicalis 17616 R-XTR-975593 https://reactome.org/PathwayBrowser/#/R-XTR-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Xenopus tropicalis 17616 R-XTR-975608 https://reactome.org/PathwayBrowser/#/R-XTR-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Xenopus tropicalis 17632 R-BTA-5340226 https://reactome.org/PathwayBrowser/#/R-BTA-5340226 CYGB dioxygenates NO IEA Bos taurus 17632 R-CEL-5340226 https://reactome.org/PathwayBrowser/#/R-CEL-5340226 CYGB dioxygenates NO IEA Caenorhabditis elegans 17632 R-CFA-5340226 https://reactome.org/PathwayBrowser/#/R-CFA-5340226 CYGB dioxygenates NO IEA Canis familiaris 17632 R-DRE-5340226 https://reactome.org/PathwayBrowser/#/R-DRE-5340226 CYGB dioxygenates NO IEA Danio rerio 17632 R-GGA-5340226 https://reactome.org/PathwayBrowser/#/R-GGA-5340226 CYGB dioxygenates NO IEA Gallus gallus 17632 R-HSA-1222723 https://reactome.org/PathwayBrowser/#/R-HSA-1222723 Nitric oxide is oxidized to nitrate TAS Homo sapiens 17632 R-HSA-432034 https://reactome.org/PathwayBrowser/#/R-HSA-432034 Aquaporin-6 passively transports anions into vesicles IEA Homo sapiens 17632 R-HSA-432036 https://reactome.org/PathwayBrowser/#/R-HSA-432036 Aquaporin-6 passively transports anions out of vesicles IEA Homo sapiens 17632 R-HSA-5340226 https://reactome.org/PathwayBrowser/#/R-HSA-5340226 CYGB dioxygenates NO TAS Homo sapiens 17632 R-MMU-5340226 https://reactome.org/PathwayBrowser/#/R-MMU-5340226 CYGB dioxygenates NO IEA Mus musculus 17632 R-RNO-5340226 https://reactome.org/PathwayBrowser/#/R-RNO-5340226 CYGB dioxygenates NO IEA Rattus norvegicus 17632 R-RNO-879862 https://reactome.org/PathwayBrowser/#/R-RNO-879862 Passive Transport of Anions into Vesicles by Aquaporin-6 (rat) TAS Rattus norvegicus 17632 R-RNO-879863 https://reactome.org/PathwayBrowser/#/R-RNO-879863 Passive Transport of Anions out of Vesicles by Aquaporin-6 (rat) TAS Rattus norvegicus 17632 R-SSC-5340226 https://reactome.org/PathwayBrowser/#/R-SSC-5340226 CYGB dioxygenates NO IEA Sus scrofa 17632 R-XTR-5340226 https://reactome.org/PathwayBrowser/#/R-XTR-5340226 CYGB dioxygenates NO IEA Xenopus tropicalis 17634 R-HSA-9769143 https://reactome.org/PathwayBrowser/#/R-HSA-9769143 NPAS4 translocates to the nucleus IEA Homo sapiens 17636 R-BTA-1605797 https://reactome.org/PathwayBrowser/#/R-BTA-1605797 SMPD1 hydrolyzes SPHM IEA Bos taurus 17636 R-BTA-1606273 https://reactome.org/PathwayBrowser/#/R-BTA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Bos taurus 17636 R-BTA-1606288 https://reactome.org/PathwayBrowser/#/R-BTA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Bos taurus 17636 R-BTA-1640164 https://reactome.org/PathwayBrowser/#/R-BTA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Bos taurus 17636 R-CEL-1605797 https://reactome.org/PathwayBrowser/#/R-CEL-1605797 SMPD1 hydrolyzes SPHM IEA Caenorhabditis elegans 17636 R-CEL-1606273 https://reactome.org/PathwayBrowser/#/R-CEL-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Caenorhabditis elegans 17636 R-CEL-1606288 https://reactome.org/PathwayBrowser/#/R-CEL-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Caenorhabditis elegans 17636 R-CEL-1640164 https://reactome.org/PathwayBrowser/#/R-CEL-1640164 ENPP7 hydrolyzes sphingomyelin IEA Caenorhabditis elegans 17636 R-CFA-1605797 https://reactome.org/PathwayBrowser/#/R-CFA-1605797 SMPD1 hydrolyzes SPHM IEA Canis familiaris 17636 R-CFA-1606273 https://reactome.org/PathwayBrowser/#/R-CFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Canis familiaris 17636 R-CFA-1606288 https://reactome.org/PathwayBrowser/#/R-CFA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Canis familiaris 17636 R-CFA-1640164 https://reactome.org/PathwayBrowser/#/R-CFA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Canis familiaris 17636 R-CFA-382553 https://reactome.org/PathwayBrowser/#/R-CFA-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Canis familiaris 17636 R-DDI-1605797 https://reactome.org/PathwayBrowser/#/R-DDI-1605797 SMPD1 hydrolyzes SPHM IEA Dictyostelium discoideum 17636 R-DDI-1606273 https://reactome.org/PathwayBrowser/#/R-DDI-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Dictyostelium discoideum 17636 R-DDI-1640164 https://reactome.org/PathwayBrowser/#/R-DDI-1640164 ENPP7 hydrolyzes sphingomyelin IEA Dictyostelium discoideum 17636 R-DME-1605797 https://reactome.org/PathwayBrowser/#/R-DME-1605797 SMPD1 hydrolyzes SPHM IEA Drosophila melanogaster 17636 R-DME-1606273 https://reactome.org/PathwayBrowser/#/R-DME-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Drosophila melanogaster 17636 R-DME-1606288 https://reactome.org/PathwayBrowser/#/R-DME-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Drosophila melanogaster 17636 R-DRE-1606273 https://reactome.org/PathwayBrowser/#/R-DRE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Danio rerio 17636 R-DRE-1606288 https://reactome.org/PathwayBrowser/#/R-DRE-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Danio rerio 17636 R-GGA-1605797 https://reactome.org/PathwayBrowser/#/R-GGA-1605797 SMPD1 hydrolyzes SPHM IEA Gallus gallus 17636 R-GGA-1606273 https://reactome.org/PathwayBrowser/#/R-GGA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Gallus gallus 17636 R-GGA-1606288 https://reactome.org/PathwayBrowser/#/R-GGA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Gallus gallus 17636 R-GGA-1640164 https://reactome.org/PathwayBrowser/#/R-GGA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Gallus gallus 17636 R-HSA-1605797 https://reactome.org/PathwayBrowser/#/R-HSA-1605797 SMPD1 hydrolyzes SPHM TAS Homo sapiens 17636 R-HSA-1606273 https://reactome.org/PathwayBrowser/#/R-HSA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) TAS Homo sapiens 17636 R-HSA-1606288 https://reactome.org/PathwayBrowser/#/R-HSA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) TAS Homo sapiens 17636 R-HSA-1640164 https://reactome.org/PathwayBrowser/#/R-HSA-1640164 ENPP7 hydrolyzes sphingomyelin TAS Homo sapiens 17636 R-HSA-193706 https://reactome.org/PathwayBrowser/#/R-HSA-193706 Production of ceramide which can activate JNK and other targets IEA Homo sapiens 17636 R-HSA-382553 https://reactome.org/PathwayBrowser/#/R-HSA-382553 ABCA7:Apo1A-mediated phospholipid efflux TAS Homo sapiens 17636 R-MMU-1605797 https://reactome.org/PathwayBrowser/#/R-MMU-1605797 SMPD1 hydrolyzes SPHM IEA Mus musculus 17636 R-MMU-1606273 https://reactome.org/PathwayBrowser/#/R-MMU-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Mus musculus 17636 R-MMU-1606288 https://reactome.org/PathwayBrowser/#/R-MMU-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Mus musculus 17636 R-MMU-1640164 https://reactome.org/PathwayBrowser/#/R-MMU-1640164 ENPP7 hydrolyzes sphingomyelin IEA Mus musculus 17636 R-MMU-382553 https://reactome.org/PathwayBrowser/#/R-MMU-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Mus musculus 17636 R-PFA-1606273 https://reactome.org/PathwayBrowser/#/R-PFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Plasmodium falciparum 17636 R-RNO-1605797 https://reactome.org/PathwayBrowser/#/R-RNO-1605797 SMPD1 hydrolyzes SPHM IEA Rattus norvegicus 17636 R-RNO-1606273 https://reactome.org/PathwayBrowser/#/R-RNO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Rattus norvegicus 17636 R-RNO-1606288 https://reactome.org/PathwayBrowser/#/R-RNO-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Rattus norvegicus 17636 R-RNO-1640164 https://reactome.org/PathwayBrowser/#/R-RNO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Rattus norvegicus 17636 R-RNO-209562 https://reactome.org/PathwayBrowser/#/R-RNO-209562 Production of ceramide which can activate JNK and other targets TAS Rattus norvegicus 17636 R-RNO-382553 https://reactome.org/PathwayBrowser/#/R-RNO-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Rattus norvegicus 17636 R-SCE-1606273 https://reactome.org/PathwayBrowser/#/R-SCE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Saccharomyces cerevisiae 17636 R-SCE-1640164 https://reactome.org/PathwayBrowser/#/R-SCE-1640164 ENPP7 hydrolyzes sphingomyelin IEA Saccharomyces cerevisiae 17636 R-SPO-1606273 https://reactome.org/PathwayBrowser/#/R-SPO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Schizosaccharomyces pombe 17636 R-SPO-1640164 https://reactome.org/PathwayBrowser/#/R-SPO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Schizosaccharomyces pombe 17636 R-SSC-1605797 https://reactome.org/PathwayBrowser/#/R-SSC-1605797 SMPD1 hydrolyzes SPHM IEA Sus scrofa 17636 R-SSC-1606273 https://reactome.org/PathwayBrowser/#/R-SSC-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Sus scrofa 17636 R-SSC-1606288 https://reactome.org/PathwayBrowser/#/R-SSC-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Sus scrofa 17636 R-SSC-1640164 https://reactome.org/PathwayBrowser/#/R-SSC-1640164 ENPP7 hydrolyzes sphingomyelin IEA Sus scrofa 17636 R-SSC-382553 https://reactome.org/PathwayBrowser/#/R-SSC-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Sus scrofa 17636 R-XTR-1605797 https://reactome.org/PathwayBrowser/#/R-XTR-1605797 SMPD1 hydrolyzes SPHM IEA Xenopus tropicalis 17636 R-XTR-1606273 https://reactome.org/PathwayBrowser/#/R-XTR-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Xenopus tropicalis 17636 R-XTR-1640164 https://reactome.org/PathwayBrowser/#/R-XTR-1640164 ENPP7 hydrolyzes sphingomyelin IEA Xenopus tropicalis 17650 R-BTA-1449687 https://reactome.org/PathwayBrowser/#/R-BTA-1449687 Corticosteroids bind to CBG in blood IEA Bos taurus 17650 R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 17650 R-BTA-194023 https://reactome.org/PathwayBrowser/#/R-BTA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Bos taurus 17650 R-BTA-4341025 https://reactome.org/PathwayBrowser/#/R-BTA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Bos taurus 17650 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 17650 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 17650 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 17650 R-BTA-5618099 https://reactome.org/PathwayBrowser/#/R-BTA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Bos taurus 17650 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 17650 R-CEL-1449687 https://reactome.org/PathwayBrowser/#/R-CEL-1449687 Corticosteroids bind to CBG in blood IEA Caenorhabditis elegans 17650 R-CFA-1449687 https://reactome.org/PathwayBrowser/#/R-CFA-1449687 Corticosteroids bind to CBG in blood IEA Canis familiaris 17650 R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 17650 R-CFA-194023 https://reactome.org/PathwayBrowser/#/R-CFA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Canis familiaris 17650 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 17650 R-CFA-5618099 https://reactome.org/PathwayBrowser/#/R-CFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Canis familiaris 17650 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 17650 R-DME-1449687 https://reactome.org/PathwayBrowser/#/R-DME-1449687 Corticosteroids bind to CBG in blood IEA Drosophila melanogaster 17650 R-DME-194023 https://reactome.org/PathwayBrowser/#/R-DME-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Drosophila melanogaster 17650 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 17650 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 17650 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 17650 R-DME-5618099 https://reactome.org/PathwayBrowser/#/R-DME-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 17650 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 17650 R-DRE-1449687 https://reactome.org/PathwayBrowser/#/R-DRE-1449687 Corticosteroids bind to CBG in blood IEA Danio rerio 17650 R-DRE-194023 https://reactome.org/PathwayBrowser/#/R-DRE-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Danio rerio 17650 R-DRE-4341025 https://reactome.org/PathwayBrowser/#/R-DRE-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Danio rerio 17650 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 17650 R-DRE-5618099 https://reactome.org/PathwayBrowser/#/R-DRE-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Danio rerio 17650 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 17650 R-GGA-194023 https://reactome.org/PathwayBrowser/#/R-GGA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Gallus gallus 17650 R-GGA-4341025 https://reactome.org/PathwayBrowser/#/R-GGA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Gallus gallus 17650 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 17650 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 17650 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 17650 R-GGA-5618099 https://reactome.org/PathwayBrowser/#/R-GGA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Gallus gallus 17650 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 17650 R-HSA-1449687 https://reactome.org/PathwayBrowser/#/R-HSA-1449687 Corticosteroids bind to CBG in blood TAS Homo sapiens 17650 R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 17650 R-HSA-194023 https://reactome.org/PathwayBrowser/#/R-HSA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR TAS Homo sapiens 17650 R-HSA-194036 https://reactome.org/PathwayBrowser/#/R-HSA-194036 Cortisol translocates from the mitochondrial matrix to the cytosol TAS Homo sapiens 17650 R-HSA-4341025 https://reactome.org/PathwayBrowser/#/R-HSA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 TAS Homo sapiens 17650 R-HSA-549493 https://reactome.org/PathwayBrowser/#/R-HSA-549493 Expression of PERIOD-2 IEA Homo sapiens 17650 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 17650 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 17650 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 17650 R-HSA-5618099 https://reactome.org/PathwayBrowser/#/R-HSA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) TAS Homo sapiens 17650 R-HSA-8848804 https://reactome.org/PathwayBrowser/#/R-HSA-8848804 HIF1A,EPAS1 promote PTK6 gene expression TAS Homo sapiens 17650 R-HSA-8856930 https://reactome.org/PathwayBrowser/#/R-HSA-8856930 EPAS1 (HIF2A) and activated NR3C1 (GCR) bind PTK6 gene TAS Homo sapiens 17650 R-HSA-8939900 https://reactome.org/PathwayBrowser/#/R-HSA-8939900 RUNX2 gene expression from proximal (P2) promoter is stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and inhibited by ESRRA:PPARG1CB and DEXA:NR3C1 IEA Homo sapiens 17650 R-HSA-9009085 https://reactome.org/PathwayBrowser/#/R-HSA-9009085 DEXA:NR3C1 complex binds RUNX2 gene proximal promoter IEA Homo sapiens 17650 R-HSA-9625693 https://reactome.org/PathwayBrowser/#/R-HSA-9625693 TRIM63 gene expression is stimulated by FOXO1 and FOXO3 IEA Homo sapiens 17650 R-HSA-9625699 https://reactome.org/PathwayBrowser/#/R-HSA-9625699 FOXO1 and NR3C1 bind TRIM63 gene promoter IEA Homo sapiens 17650 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 17650 R-HSA-9769345 https://reactome.org/PathwayBrowser/#/R-HSA-9769345 Activated glucocorticoid receptor represses NPAS4 gene transcription IEA Homo sapiens 17650 R-HSA-9769347 https://reactome.org/PathwayBrowser/#/R-HSA-9769347 Activated glucocorticoid receptor binds NPAS4 gene promoter IEA Homo sapiens 17650 R-MMU-1449687 https://reactome.org/PathwayBrowser/#/R-MMU-1449687 Corticosteroids bind to CBG in blood IEA Mus musculus 17650 R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 17650 R-MMU-194023 https://reactome.org/PathwayBrowser/#/R-MMU-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Mus musculus 17650 R-MMU-4341025 https://reactome.org/PathwayBrowser/#/R-MMU-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Mus musculus 17650 R-MMU-549409 https://reactome.org/PathwayBrowser/#/R-MMU-549409 Expression of Period-2 (Per2) TAS Mus musculus 17650 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 17650 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 17650 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 17650 R-MMU-5618099 https://reactome.org/PathwayBrowser/#/R-MMU-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Mus musculus 17650 R-MMU-9009091 https://reactome.org/PathwayBrowser/#/R-MMU-9009091 Nr3c1:DEXA binds Runx2 proximal promoter TAS Mus musculus 17650 R-MMU-9009102 https://reactome.org/PathwayBrowser/#/R-MMU-9009102 Runx2 gene expression from proximal (P2) promoter is stimulated by Runx2-P2 and inhibited by DEXA:Nr3c1 TAS Mus musculus 17650 R-MMU-9625700 https://reactome.org/PathwayBrowser/#/R-MMU-9625700 Foxo1 and Nr3c1 bind Trim63 gene promoter TAS Mus musculus 17650 R-MMU-9625730 https://reactome.org/PathwayBrowser/#/R-MMU-9625730 Trim63 gene expression is activated by Foxo1 and Nr3c1 TAS Mus musculus 17650 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 17650 R-MMU-9769703 https://reactome.org/PathwayBrowser/#/R-MMU-9769703 Activated glucocorticoid receptor binds Npas4 gene promoter TAS Mus musculus 17650 R-MMU-9769713 https://reactome.org/PathwayBrowser/#/R-MMU-9769713 Activated glucocorticoid receptor represses Npas4 gene transcription TAS Mus musculus 17650 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 17650 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 17650 R-PFA-5618099 https://reactome.org/PathwayBrowser/#/R-PFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 17650 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 17650 R-RNO-1449687 https://reactome.org/PathwayBrowser/#/R-RNO-1449687 Corticosteroids bind to CBG in blood IEA Rattus norvegicus 17650 R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 17650 R-RNO-194023 https://reactome.org/PathwayBrowser/#/R-RNO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Rattus norvegicus 17650 R-RNO-4341025 https://reactome.org/PathwayBrowser/#/R-RNO-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Rattus norvegicus 17650 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 17650 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 17650 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 17650 R-RNO-5618099 https://reactome.org/PathwayBrowser/#/R-RNO-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Rattus norvegicus 17650 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 17650 R-SPO-194023 https://reactome.org/PathwayBrowser/#/R-SPO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Schizosaccharomyces pombe 17650 R-SSC-1449687 https://reactome.org/PathwayBrowser/#/R-SSC-1449687 Corticosteroids bind to CBG in blood IEA Sus scrofa 17650 R-SSC-193997 https://reactome.org/PathwayBrowser/#/R-SSC-193997 CYP11B1 oxidises 11DCORT IEA Sus scrofa 17650 R-SSC-194023 https://reactome.org/PathwayBrowser/#/R-SSC-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Sus scrofa 17650 R-SSC-4341025 https://reactome.org/PathwayBrowser/#/R-SSC-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Sus scrofa 17650 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 17650 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 17650 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 17650 R-SSC-5618099 https://reactome.org/PathwayBrowser/#/R-SSC-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Sus scrofa 17650 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 17650 R-XTR-1449687 https://reactome.org/PathwayBrowser/#/R-XTR-1449687 Corticosteroids bind to CBG in blood IEA Xenopus tropicalis 17650 R-XTR-193997 https://reactome.org/PathwayBrowser/#/R-XTR-193997 CYP11B1 oxidises 11DCORT IEA Xenopus tropicalis 17650 R-XTR-194023 https://reactome.org/PathwayBrowser/#/R-XTR-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Xenopus tropicalis 17650 R-XTR-4341025 https://reactome.org/PathwayBrowser/#/R-XTR-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Xenopus tropicalis 17650 R-XTR-5618099 https://reactome.org/PathwayBrowser/#/R-XTR-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 17650 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 17654 R-HSA-9661710 https://reactome.org/PathwayBrowser/#/R-HSA-9661710 An unknown oxidase oxidises D-UBGN to UBN TAS Homo sapiens 17654 R-HSA-9661726 https://reactome.org/PathwayBrowser/#/R-HSA-9661726 An unknown reductase reduces D-UBGN to STBN TAS Homo sapiens 17654 R-HSA-9661745 https://reactome.org/PathwayBrowser/#/R-HSA-9661745 An unknown BILR reduces BIL to D-UBGN TAS Homo sapiens 17659 R-BTA-159179 https://reactome.org/PathwayBrowser/#/R-BTA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Bos taurus 17659 R-BTA-159194 https://reactome.org/PathwayBrowser/#/R-BTA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Bos taurus 17659 R-BTA-174916 https://reactome.org/PathwayBrowser/#/R-BTA-174916 Formation of N-glucuronides IEA Bos taurus 17659 R-BTA-1981120 https://reactome.org/PathwayBrowser/#/R-BTA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Bos taurus 17659 R-BTA-1981128 https://reactome.org/PathwayBrowser/#/R-BTA-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Bos taurus 17659 R-BTA-1981157 https://reactome.org/PathwayBrowser/#/R-BTA-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Bos taurus 17659 R-BTA-5173005 https://reactome.org/PathwayBrowser/#/R-BTA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Bos taurus 17659 R-BTA-6785933 https://reactome.org/PathwayBrowser/#/R-BTA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Bos taurus 17659 R-BTA-8879117 https://reactome.org/PathwayBrowser/#/R-BTA-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Bos taurus 17659 R-BTA-8931648 https://reactome.org/PathwayBrowser/#/R-BTA-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Bos taurus 17659 R-CEL-1981120 https://reactome.org/PathwayBrowser/#/R-CEL-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Caenorhabditis elegans 17659 R-CEL-1981128 https://reactome.org/PathwayBrowser/#/R-CEL-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Caenorhabditis elegans 17659 R-CEL-1981157 https://reactome.org/PathwayBrowser/#/R-CEL-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Caenorhabditis elegans 17659 R-CEL-5173005 https://reactome.org/PathwayBrowser/#/R-CEL-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Caenorhabditis elegans 17659 R-CEL-6785933 https://reactome.org/PathwayBrowser/#/R-CEL-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Caenorhabditis elegans 17659 R-CFA-1981120 https://reactome.org/PathwayBrowser/#/R-CFA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Canis familiaris 17659 R-CFA-1981128 https://reactome.org/PathwayBrowser/#/R-CFA-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Canis familiaris 17659 R-CFA-1981157 https://reactome.org/PathwayBrowser/#/R-CFA-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Canis familiaris 17659 R-CFA-5173005 https://reactome.org/PathwayBrowser/#/R-CFA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Canis familiaris 17659 R-CFA-6785933 https://reactome.org/PathwayBrowser/#/R-CFA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Canis familiaris 17659 R-CFA-8879117 https://reactome.org/PathwayBrowser/#/R-CFA-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Canis familiaris 17659 R-CFA-8931648 https://reactome.org/PathwayBrowser/#/R-CFA-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Canis familiaris 17659 R-CFA-8941701 https://reactome.org/PathwayBrowser/#/R-CFA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Canis familiaris 17659 R-DDI-159179 https://reactome.org/PathwayBrowser/#/R-DDI-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Dictyostelium discoideum 17659 R-DDI-159194 https://reactome.org/PathwayBrowser/#/R-DDI-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Dictyostelium discoideum 17659 R-DDI-174916 https://reactome.org/PathwayBrowser/#/R-DDI-174916 Formation of N-glucuronides IEA Dictyostelium discoideum 17659 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 17659 R-DDI-8941701 https://reactome.org/PathwayBrowser/#/R-DDI-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Dictyostelium discoideum 17659 R-DDI-9632038 https://reactome.org/PathwayBrowser/#/R-DDI-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Dictyostelium discoideum 17659 R-DDI-9632039 https://reactome.org/PathwayBrowser/#/R-DDI-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Dictyostelium discoideum 17659 R-DDI-9749977 https://reactome.org/PathwayBrowser/#/R-DDI-9749977 UGT1A6 glucuronates ST IEA Dictyostelium discoideum 17659 R-DME-1981120 https://reactome.org/PathwayBrowser/#/R-DME-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Drosophila melanogaster 17659 R-DME-1981128 https://reactome.org/PathwayBrowser/#/R-DME-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Drosophila melanogaster 17659 R-DME-1981157 https://reactome.org/PathwayBrowser/#/R-DME-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Drosophila melanogaster 17659 R-DME-5173005 https://reactome.org/PathwayBrowser/#/R-DME-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Drosophila melanogaster 17659 R-DRE-1981120 https://reactome.org/PathwayBrowser/#/R-DRE-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Danio rerio 17659 R-DRE-1981128 https://reactome.org/PathwayBrowser/#/R-DRE-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Danio rerio 17659 R-DRE-1981157 https://reactome.org/PathwayBrowser/#/R-DRE-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Danio rerio 17659 R-DRE-5173005 https://reactome.org/PathwayBrowser/#/R-DRE-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Danio rerio 17659 R-DRE-6785933 https://reactome.org/PathwayBrowser/#/R-DRE-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Danio rerio 17659 R-DRE-8879117 https://reactome.org/PathwayBrowser/#/R-DRE-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Danio rerio 17659 R-DRE-8931648 https://reactome.org/PathwayBrowser/#/R-DRE-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Danio rerio 17659 R-GGA-159179 https://reactome.org/PathwayBrowser/#/R-GGA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Gallus gallus 17659 R-GGA-159194 https://reactome.org/PathwayBrowser/#/R-GGA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Gallus gallus 17659 R-GGA-174916 https://reactome.org/PathwayBrowser/#/R-GGA-174916 Formation of N-glucuronides IEA Gallus gallus 17659 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 17659 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Gallus gallus 17659 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus 17659 R-GGA-6785933 https://reactome.org/PathwayBrowser/#/R-GGA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Gallus gallus 17659 R-GGA-8879117 https://reactome.org/PathwayBrowser/#/R-GGA-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Gallus gallus 17659 R-GGA-8931648 https://reactome.org/PathwayBrowser/#/R-GGA-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Gallus gallus 17659 R-GGA-8941701 https://reactome.org/PathwayBrowser/#/R-GGA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Gallus gallus 17659 R-GGA-9632038 https://reactome.org/PathwayBrowser/#/R-GGA-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Gallus gallus 17659 R-GGA-9632039 https://reactome.org/PathwayBrowser/#/R-GGA-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Gallus gallus 17659 R-GGA-9749977 https://reactome.org/PathwayBrowser/#/R-GGA-9749977 UGT1A6 glucuronates ST IEA Gallus gallus 17659 R-HSA-159179 https://reactome.org/PathwayBrowser/#/R-HSA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG TAS Homo sapiens 17659 R-HSA-159194 https://reactome.org/PathwayBrowser/#/R-HSA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG TAS Homo sapiens 17659 R-HSA-174916 https://reactome.org/PathwayBrowser/#/R-HSA-174916 Formation of N-glucuronides TAS Homo sapiens 17659 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 17659 R-HSA-1912353 https://reactome.org/PathwayBrowser/#/R-HSA-1912353 Glucosylation of Pre-NOTCH by POGLUT1 IEA Homo sapiens 17659 R-HSA-1981120 https://reactome.org/PathwayBrowser/#/R-HSA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. TAS Homo sapiens 17659 R-HSA-1981128 https://reactome.org/PathwayBrowser/#/R-HSA-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 TAS Homo sapiens 17659 R-HSA-1981157 https://reactome.org/PathwayBrowser/#/R-HSA-1981157 Glucosylation of collagen propeptide hydroxylysines TAS Homo sapiens 17659 R-HSA-5173005 https://reactome.org/PathwayBrowser/#/R-HSA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins TAS Homo sapiens 17659 R-HSA-6785933 https://reactome.org/PathwayBrowser/#/R-HSA-6785933 UGT8 transfers Gal from UDP-Gal to CERA TAS Homo sapiens 17659 R-HSA-8879117 https://reactome.org/PathwayBrowser/#/R-HSA-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 TAS Homo sapiens 17659 R-HSA-8931648 https://reactome.org/PathwayBrowser/#/R-HSA-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 TAS Homo sapiens 17659 R-HSA-8941701 https://reactome.org/PathwayBrowser/#/R-HSA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN TAS Homo sapiens 17659 R-HSA-9632038 https://reactome.org/PathwayBrowser/#/R-HSA-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG TAS Homo sapiens 17659 R-HSA-9632039 https://reactome.org/PathwayBrowser/#/R-HSA-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG TAS Homo sapiens 17659 R-HSA-9683648 https://reactome.org/PathwayBrowser/#/R-HSA-9683648 Spike trimer glycoside chains are extended TAS Homo sapiens 17659 R-HSA-9683760 https://reactome.org/PathwayBrowser/#/R-HSA-9683760 GalNAc is transferred onto 3a TAS Homo sapiens 17659 R-HSA-9694438 https://reactome.org/PathwayBrowser/#/R-HSA-9694438 GalNAc is transferred onto 3a IEA Homo sapiens 17659 R-HSA-9749977 https://reactome.org/PathwayBrowser/#/R-HSA-9749977 UGT1A6 glucuronates ST TAS Homo sapiens 17659 R-MMU-159179 https://reactome.org/PathwayBrowser/#/R-MMU-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Mus musculus 17659 R-MMU-159194 https://reactome.org/PathwayBrowser/#/R-MMU-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Mus musculus 17659 R-MMU-174916 https://reactome.org/PathwayBrowser/#/R-MMU-174916 Formation of N-glucuronides IEA Mus musculus 17659 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 17659 R-MMU-1981120 https://reactome.org/PathwayBrowser/#/R-MMU-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Mus musculus 17659 R-MMU-1981128 https://reactome.org/PathwayBrowser/#/R-MMU-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Mus musculus 17659 R-MMU-1981157 https://reactome.org/PathwayBrowser/#/R-MMU-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Mus musculus 17659 R-MMU-2023179 https://reactome.org/PathwayBrowser/#/R-MMU-2023179 Glucosylation of Pre-Notch by Poglut1 TAS Mus musculus 17659 R-MMU-5173005 https://reactome.org/PathwayBrowser/#/R-MMU-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Mus musculus 17659 R-MMU-6785933 https://reactome.org/PathwayBrowser/#/R-MMU-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Mus musculus 17659 R-MMU-8879117 https://reactome.org/PathwayBrowser/#/R-MMU-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Mus musculus 17659 R-MMU-8931648 https://reactome.org/PathwayBrowser/#/R-MMU-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Mus musculus 17659 R-MMU-8941701 https://reactome.org/PathwayBrowser/#/R-MMU-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Mus musculus 17659 R-MMU-9632038 https://reactome.org/PathwayBrowser/#/R-MMU-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Mus musculus 17659 R-MMU-9632039 https://reactome.org/PathwayBrowser/#/R-MMU-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Mus musculus 17659 R-MMU-9749977 https://reactome.org/PathwayBrowser/#/R-MMU-9749977 UGT1A6 glucuronates ST IEA Mus musculus 17659 R-RNO-159179 https://reactome.org/PathwayBrowser/#/R-RNO-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Rattus norvegicus 17659 R-RNO-159194 https://reactome.org/PathwayBrowser/#/R-RNO-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Rattus norvegicus 17659 R-RNO-174916 https://reactome.org/PathwayBrowser/#/R-RNO-174916 Formation of N-glucuronides IEA Rattus norvegicus 17659 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 17659 R-RNO-1981120 https://reactome.org/PathwayBrowser/#/R-RNO-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Rattus norvegicus 17659 R-RNO-1981128 https://reactome.org/PathwayBrowser/#/R-RNO-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Rattus norvegicus 17659 R-RNO-1981157 https://reactome.org/PathwayBrowser/#/R-RNO-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Rattus norvegicus 17659 R-RNO-5173005 https://reactome.org/PathwayBrowser/#/R-RNO-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Rattus norvegicus 17659 R-RNO-6785933 https://reactome.org/PathwayBrowser/#/R-RNO-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Rattus norvegicus 17659 R-RNO-8879117 https://reactome.org/PathwayBrowser/#/R-RNO-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Rattus norvegicus 17659 R-RNO-8931648 https://reactome.org/PathwayBrowser/#/R-RNO-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Rattus norvegicus 17659 R-RNO-8941701 https://reactome.org/PathwayBrowser/#/R-RNO-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Rattus norvegicus 17659 R-RNO-9632038 https://reactome.org/PathwayBrowser/#/R-RNO-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Rattus norvegicus 17659 R-RNO-9632039 https://reactome.org/PathwayBrowser/#/R-RNO-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Rattus norvegicus 17659 R-RNO-9749977 https://reactome.org/PathwayBrowser/#/R-RNO-9749977 UGT1A6 glucuronates ST IEA Rattus norvegicus 17659 R-SSC-159179 https://reactome.org/PathwayBrowser/#/R-SSC-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Sus scrofa 17659 R-SSC-159194 https://reactome.org/PathwayBrowser/#/R-SSC-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Sus scrofa 17659 R-SSC-174916 https://reactome.org/PathwayBrowser/#/R-SSC-174916 Formation of N-glucuronides IEA Sus scrofa 17659 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Sus scrofa 17659 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa 17659 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa 17659 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa 17659 R-SSC-6785933 https://reactome.org/PathwayBrowser/#/R-SSC-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Sus scrofa 17659 R-SSC-8879117 https://reactome.org/PathwayBrowser/#/R-SSC-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Sus scrofa 17659 R-SSC-8931648 https://reactome.org/PathwayBrowser/#/R-SSC-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Sus scrofa 17659 R-XTR-1981120 https://reactome.org/PathwayBrowser/#/R-XTR-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Xenopus tropicalis 17659 R-XTR-1981128 https://reactome.org/PathwayBrowser/#/R-XTR-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Xenopus tropicalis 17659 R-XTR-1981157 https://reactome.org/PathwayBrowser/#/R-XTR-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Xenopus tropicalis 17659 R-XTR-5173005 https://reactome.org/PathwayBrowser/#/R-XTR-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Xenopus tropicalis 17659 R-XTR-8879117 https://reactome.org/PathwayBrowser/#/R-XTR-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Xenopus tropicalis 17659 R-XTR-8931648 https://reactome.org/PathwayBrowser/#/R-XTR-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Xenopus tropicalis 17682 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 17682 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 17682 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 17682 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 17682 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 17682 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 17682 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 17682 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 17682 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 17682 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 17688 R-BTA-174916 https://reactome.org/PathwayBrowser/#/R-BTA-174916 Formation of N-glucuronides IEA Bos taurus 17688 R-DDI-174916 https://reactome.org/PathwayBrowser/#/R-DDI-174916 Formation of N-glucuronides IEA Dictyostelium discoideum 17688 R-GGA-174916 https://reactome.org/PathwayBrowser/#/R-GGA-174916 Formation of N-glucuronides IEA Gallus gallus 17688 R-HSA-174916 https://reactome.org/PathwayBrowser/#/R-HSA-174916 Formation of N-glucuronides TAS Homo sapiens 17688 R-MMU-174916 https://reactome.org/PathwayBrowser/#/R-MMU-174916 Formation of N-glucuronides IEA Mus musculus 17688 R-RNO-174916 https://reactome.org/PathwayBrowser/#/R-RNO-174916 Formation of N-glucuronides IEA Rattus norvegicus 17688 R-SSC-174916 https://reactome.org/PathwayBrowser/#/R-SSC-174916 Formation of N-glucuronides IEA Sus scrofa 176905 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 176905 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 176905 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 176905 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 176905 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 176905 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 176905 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 176960 R-BTA-9750656 https://reactome.org/PathwayBrowser/#/R-BTA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Bos taurus 176960 R-CEL-9750656 https://reactome.org/PathwayBrowser/#/R-CEL-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Caenorhabditis elegans 176960 R-CFA-9750656 https://reactome.org/PathwayBrowser/#/R-CFA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Canis familiaris 176960 R-DDI-9749977 https://reactome.org/PathwayBrowser/#/R-DDI-9749977 UGT1A6 glucuronates ST IEA Dictyostelium discoideum 176960 R-DDI-9750656 https://reactome.org/PathwayBrowser/#/R-DDI-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Dictyostelium discoideum 176960 R-DME-9750656 https://reactome.org/PathwayBrowser/#/R-DME-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Drosophila melanogaster 176960 R-DRE-9750656 https://reactome.org/PathwayBrowser/#/R-DRE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Danio rerio 176960 R-GGA-9749977 https://reactome.org/PathwayBrowser/#/R-GGA-9749977 UGT1A6 glucuronates ST IEA Gallus gallus 176960 R-GGA-9750656 https://reactome.org/PathwayBrowser/#/R-GGA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Gallus gallus 176960 R-HSA-9749977 https://reactome.org/PathwayBrowser/#/R-HSA-9749977 UGT1A6 glucuronates ST TAS Homo sapiens 176960 R-HSA-9750656 https://reactome.org/PathwayBrowser/#/R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells TAS Homo sapiens 176960 R-HSA-9757459 https://reactome.org/PathwayBrowser/#/R-HSA-9757459 ST metabolites diffuse out of ER lumen TAS Homo sapiens 176960 R-MMU-9749977 https://reactome.org/PathwayBrowser/#/R-MMU-9749977 UGT1A6 glucuronates ST IEA Mus musculus 176960 R-MMU-9750656 https://reactome.org/PathwayBrowser/#/R-MMU-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Mus musculus 176960 R-RNO-9749977 https://reactome.org/PathwayBrowser/#/R-RNO-9749977 UGT1A6 glucuronates ST IEA Rattus norvegicus 176960 R-RNO-9750656 https://reactome.org/PathwayBrowser/#/R-RNO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Rattus norvegicus 176960 R-SCE-9750656 https://reactome.org/PathwayBrowser/#/R-SCE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Saccharomyces cerevisiae 176960 R-SPO-9750656 https://reactome.org/PathwayBrowser/#/R-SPO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Schizosaccharomyces pombe 176960 R-SSC-9750656 https://reactome.org/PathwayBrowser/#/R-SSC-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Sus scrofa 176960 R-XTR-9750656 https://reactome.org/PathwayBrowser/#/R-XTR-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Xenopus tropicalis 17697 R-BTA-209792 https://reactome.org/PathwayBrowser/#/R-BTA-209792 N-acetylation of serotonin IEA Bos taurus 17697 R-BTA-209821 https://reactome.org/PathwayBrowser/#/R-BTA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Bos taurus 17697 R-CFA-209792 https://reactome.org/PathwayBrowser/#/R-CFA-209792 N-acetylation of serotonin IEA Canis familiaris 17697 R-CFA-209821 https://reactome.org/PathwayBrowser/#/R-CFA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Canis familiaris 17697 R-DDI-209821 https://reactome.org/PathwayBrowser/#/R-DDI-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Dictyostelium discoideum 17697 R-DRE-209792 https://reactome.org/PathwayBrowser/#/R-DRE-209792 N-acetylation of serotonin IEA Danio rerio 17697 R-DRE-209821 https://reactome.org/PathwayBrowser/#/R-DRE-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Danio rerio 17697 R-GGA-209792 https://reactome.org/PathwayBrowser/#/R-GGA-209792 N-acetylation of serotonin IEA Gallus gallus 17697 R-GGA-209821 https://reactome.org/PathwayBrowser/#/R-GGA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Gallus gallus 17697 R-HSA-209792 https://reactome.org/PathwayBrowser/#/R-HSA-209792 N-acetylation of serotonin TAS Homo sapiens 17697 R-HSA-209821 https://reactome.org/PathwayBrowser/#/R-HSA-209821 Methylation of N-acetyl-5-HT to form melatonin TAS Homo sapiens 17697 R-MMU-209792 https://reactome.org/PathwayBrowser/#/R-MMU-209792 N-acetylation of serotonin IEA Mus musculus 17697 R-MMU-209821 https://reactome.org/PathwayBrowser/#/R-MMU-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Mus musculus 17697 R-RNO-209792 https://reactome.org/PathwayBrowser/#/R-RNO-209792 N-acetylation of serotonin IEA Rattus norvegicus 17697 R-RNO-209821 https://reactome.org/PathwayBrowser/#/R-RNO-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Rattus norvegicus 17697 R-SCE-209792 https://reactome.org/PathwayBrowser/#/R-SCE-209792 N-acetylation of serotonin IEA Saccharomyces cerevisiae 17697 R-SPO-209792 https://reactome.org/PathwayBrowser/#/R-SPO-209792 N-acetylation of serotonin IEA Schizosaccharomyces pombe 17697 R-SSC-209792 https://reactome.org/PathwayBrowser/#/R-SSC-209792 N-acetylation of serotonin IEA Sus scrofa 17697 R-SSC-209821 https://reactome.org/PathwayBrowser/#/R-SSC-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Sus scrofa 17697 R-XTR-209821 https://reactome.org/PathwayBrowser/#/R-XTR-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Xenopus tropicalis 176976 R-BTA-9750656 https://reactome.org/PathwayBrowser/#/R-BTA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Bos taurus 176976 R-CEL-9750656 https://reactome.org/PathwayBrowser/#/R-CEL-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Caenorhabditis elegans 176976 R-CFA-9750656 https://reactome.org/PathwayBrowser/#/R-CFA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Canis familiaris 176976 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 176976 R-DDI-9750656 https://reactome.org/PathwayBrowser/#/R-DDI-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Dictyostelium discoideum 176976 R-DME-9750656 https://reactome.org/PathwayBrowser/#/R-DME-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Drosophila melanogaster 176976 R-DRE-9750656 https://reactome.org/PathwayBrowser/#/R-DRE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Danio rerio 176976 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 176976 R-GGA-9750656 https://reactome.org/PathwayBrowser/#/R-GGA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Gallus gallus 176976 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 176976 R-HSA-9750656 https://reactome.org/PathwayBrowser/#/R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells TAS Homo sapiens 176976 R-HSA-9757459 https://reactome.org/PathwayBrowser/#/R-HSA-9757459 ST metabolites diffuse out of ER lumen TAS Homo sapiens 176976 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 176976 R-MMU-9750656 https://reactome.org/PathwayBrowser/#/R-MMU-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Mus musculus 176976 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 176976 R-RNO-9750656 https://reactome.org/PathwayBrowser/#/R-RNO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Rattus norvegicus 176976 R-SCE-9750656 https://reactome.org/PathwayBrowser/#/R-SCE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Saccharomyces cerevisiae 176976 R-SPO-9750656 https://reactome.org/PathwayBrowser/#/R-SPO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Schizosaccharomyces pombe 176976 R-SSC-9750656 https://reactome.org/PathwayBrowser/#/R-SSC-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Sus scrofa 176976 R-XTR-9750656 https://reactome.org/PathwayBrowser/#/R-XTR-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Xenopus tropicalis 17698 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 17698 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 17698 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 17698 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 17698 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 17698 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 17698 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 17698 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 17698 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 17698 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 17698 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 17698 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 17698 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 17698 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 17698 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 17698 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 17698 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 17698 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 17698 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 17698 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 17698 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 17698 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 17698 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 17698 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 17698 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 17698 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 17698 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 17698 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 17698 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 17698 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 17698 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 17698 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 17698 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 17698 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 17698 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 17698 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 17698 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 17698 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 17698 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 17698 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 17698 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 17698 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 17703 R-BTA-176494 https://reactome.org/PathwayBrowser/#/R-BTA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Bos taurus 17703 R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 17703 R-BTA-192123 https://reactome.org/PathwayBrowser/#/R-BTA-192123 CYP27A1 27-hydroxylates CHOL IEA Bos taurus 17703 R-CFA-176494 https://reactome.org/PathwayBrowser/#/R-CFA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Canis familiaris 17703 R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 17703 R-CFA-192123 https://reactome.org/PathwayBrowser/#/R-CFA-192123 CYP27A1 27-hydroxylates CHOL IEA Canis familiaris 17703 R-DME-176494 https://reactome.org/PathwayBrowser/#/R-DME-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Drosophila melanogaster 17703 R-DRE-176494 https://reactome.org/PathwayBrowser/#/R-DRE-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Danio rerio 17703 R-GGA-176494 https://reactome.org/PathwayBrowser/#/R-GGA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Gallus gallus 17703 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 17703 R-HSA-176494 https://reactome.org/PathwayBrowser/#/R-HSA-176494 SULTs transfer (SO4)2- group to 27HCHOL TAS Homo sapiens 17703 R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 17703 R-HSA-192123 https://reactome.org/PathwayBrowser/#/R-HSA-192123 CYP27A1 27-hydroxylates CHOL TAS Homo sapiens 17703 R-HSA-193801 https://reactome.org/PathwayBrowser/#/R-HSA-193801 Influx of 27-hydroxycholesterol TAS Homo sapiens 17703 R-HSA-193812 https://reactome.org/PathwayBrowser/#/R-HSA-193812 Efflux of 27-hydroxycholesterol TAS Homo sapiens 17703 R-MMU-176494 https://reactome.org/PathwayBrowser/#/R-MMU-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Mus musculus 17703 R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 17703 R-MMU-192123 https://reactome.org/PathwayBrowser/#/R-MMU-192123 CYP27A1 27-hydroxylates CHOL IEA Mus musculus 17703 R-RNO-176494 https://reactome.org/PathwayBrowser/#/R-RNO-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Rattus norvegicus 17703 R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 17703 R-RNO-192123 https://reactome.org/PathwayBrowser/#/R-RNO-192123 CYP27A1 27-hydroxylates CHOL IEA Rattus norvegicus 17703 R-SSC-176494 https://reactome.org/PathwayBrowser/#/R-SSC-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Sus scrofa 17703 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 17703 R-SSC-192123 https://reactome.org/PathwayBrowser/#/R-SSC-192123 CYP27A1 27-hydroxylates CHOL IEA Sus scrofa 17703 R-XTR-176494 https://reactome.org/PathwayBrowser/#/R-XTR-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Xenopus tropicalis 17703 R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 17712 R-BTA-74247 https://reactome.org/PathwayBrowser/#/R-BTA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Bos taurus 17712 R-BTA-74255 https://reactome.org/PathwayBrowser/#/R-BTA-74255 Guanine + H2O => Xanthine + NH4+ IEA Bos taurus 17712 R-BTA-74258 https://reactome.org/PathwayBrowser/#/R-BTA-74258 XDH oxidizes xanthine to form urate IEA Bos taurus 17712 R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 17712 R-BTA-9727349 https://reactome.org/PathwayBrowser/#/R-BTA-9727349 XDH dehydrogenates xanthine to form urate IEA Bos taurus 17712 R-CEL-74247 https://reactome.org/PathwayBrowser/#/R-CEL-74247 XDH oxidizes hypoxanthine to form xanthine IEA Caenorhabditis elegans 17712 R-CEL-74258 https://reactome.org/PathwayBrowser/#/R-CEL-74258 XDH oxidizes xanthine to form urate IEA Caenorhabditis elegans 17712 R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 17712 R-CEL-9727349 https://reactome.org/PathwayBrowser/#/R-CEL-9727349 XDH dehydrogenates xanthine to form urate IEA Caenorhabditis elegans 17712 R-CFA-74247 https://reactome.org/PathwayBrowser/#/R-CFA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Canis familiaris 17712 R-CFA-74255 https://reactome.org/PathwayBrowser/#/R-CFA-74255 Guanine + H2O => Xanthine + NH4+ IEA Canis familiaris 17712 R-CFA-74258 https://reactome.org/PathwayBrowser/#/R-CFA-74258 XDH oxidizes xanthine to form urate IEA Canis familiaris 17712 R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 17712 R-CFA-9727349 https://reactome.org/PathwayBrowser/#/R-CFA-9727349 XDH dehydrogenates xanthine to form urate IEA Canis familiaris 17712 R-DDI-74247 https://reactome.org/PathwayBrowser/#/R-DDI-74247 XDH oxidizes hypoxanthine to form xanthine IEA Dictyostelium discoideum 17712 R-DDI-74255 https://reactome.org/PathwayBrowser/#/R-DDI-74255 Guanine + H2O => Xanthine + NH4+ IEA Dictyostelium discoideum 17712 R-DDI-74258 https://reactome.org/PathwayBrowser/#/R-DDI-74258 XDH oxidizes xanthine to form urate IEA Dictyostelium discoideum 17712 R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 17712 R-DDI-9727349 https://reactome.org/PathwayBrowser/#/R-DDI-9727349 XDH dehydrogenates xanthine to form urate IEA Dictyostelium discoideum 17712 R-DME-74247 https://reactome.org/PathwayBrowser/#/R-DME-74247 XDH oxidizes hypoxanthine to form xanthine IEA Drosophila melanogaster 17712 R-DME-74255 https://reactome.org/PathwayBrowser/#/R-DME-74255 Guanine + H2O => Xanthine + NH4+ IEA Drosophila melanogaster 17712 R-DME-74258 https://reactome.org/PathwayBrowser/#/R-DME-74258 XDH oxidizes xanthine to form urate IEA Drosophila melanogaster 17712 R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 17712 R-DME-9727349 https://reactome.org/PathwayBrowser/#/R-DME-9727349 XDH dehydrogenates xanthine to form urate IEA Drosophila melanogaster 17712 R-DRE-74255 https://reactome.org/PathwayBrowser/#/R-DRE-74255 Guanine + H2O => Xanthine + NH4+ IEA Danio rerio 17712 R-GGA-421158 https://reactome.org/PathwayBrowser/#/R-GGA-421158 xanthine + H2O + NAD+ => urate + NADH + H+ TAS Gallus gallus 17712 R-GGA-421161 https://reactome.org/PathwayBrowser/#/R-GGA-421161 hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ TAS Gallus gallus 17712 R-GGA-74247 https://reactome.org/PathwayBrowser/#/R-GGA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Gallus gallus 17712 R-GGA-74255 https://reactome.org/PathwayBrowser/#/R-GGA-74255 Guanine + H2O => Xanthine + NH4+ IEA Gallus gallus 17712 R-GGA-74258 https://reactome.org/PathwayBrowser/#/R-GGA-74258 XDH oxidizes xanthine to form urate IEA Gallus gallus 17712 R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 17712 R-GGA-9727349 https://reactome.org/PathwayBrowser/#/R-GGA-9727349 XDH dehydrogenates xanthine to form urate IEA Gallus gallus 17712 R-HSA-74247 https://reactome.org/PathwayBrowser/#/R-HSA-74247 XDH oxidizes hypoxanthine to form xanthine TAS Homo sapiens 17712 R-HSA-74255 https://reactome.org/PathwayBrowser/#/R-HSA-74255 Guanine + H2O => Xanthine + NH4+ TAS Homo sapiens 17712 R-HSA-74258 https://reactome.org/PathwayBrowser/#/R-HSA-74258 XDH oxidizes xanthine to form urate TAS Homo sapiens 17712 R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 17712 R-HSA-9727349 https://reactome.org/PathwayBrowser/#/R-HSA-9727349 XDH dehydrogenates xanthine to form urate TAS Homo sapiens 17712 R-MMU-74247 https://reactome.org/PathwayBrowser/#/R-MMU-74247 XDH oxidizes hypoxanthine to form xanthine IEA Mus musculus 17712 R-MMU-74255 https://reactome.org/PathwayBrowser/#/R-MMU-74255 Guanine + H2O => Xanthine + NH4+ IEA Mus musculus 17712 R-MMU-74258 https://reactome.org/PathwayBrowser/#/R-MMU-74258 XDH oxidizes xanthine to form urate IEA Mus musculus 17712 R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 17712 R-MMU-9727349 https://reactome.org/PathwayBrowser/#/R-MMU-9727349 XDH dehydrogenates xanthine to form urate IEA Mus musculus 17712 R-RNO-74247 https://reactome.org/PathwayBrowser/#/R-RNO-74247 XDH oxidizes hypoxanthine to form xanthine IEA Rattus norvegicus 17712 R-RNO-74255 https://reactome.org/PathwayBrowser/#/R-RNO-74255 Guanine + H2O => Xanthine + NH4+ IEA Rattus norvegicus 17712 R-RNO-74258 https://reactome.org/PathwayBrowser/#/R-RNO-74258 XDH oxidizes xanthine to form urate IEA Rattus norvegicus 17712 R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 17712 R-RNO-9727349 https://reactome.org/PathwayBrowser/#/R-RNO-9727349 XDH dehydrogenates xanthine to form urate IEA Rattus norvegicus 17712 R-SCE-74255 https://reactome.org/PathwayBrowser/#/R-SCE-74255 Guanine + H2O => Xanthine + NH4+ IEA Saccharomyces cerevisiae 17712 R-SPO-74255 https://reactome.org/PathwayBrowser/#/R-SPO-74255 Guanine + H2O => Xanthine + NH4+ IEA Schizosaccharomyces pombe 17712 R-SSC-74247 https://reactome.org/PathwayBrowser/#/R-SSC-74247 XDH oxidizes hypoxanthine to form xanthine IEA Sus scrofa 17712 R-SSC-74255 https://reactome.org/PathwayBrowser/#/R-SSC-74255 Guanine + H2O => Xanthine + NH4+ IEA Sus scrofa 17712 R-SSC-74258 https://reactome.org/PathwayBrowser/#/R-SSC-74258 XDH oxidizes xanthine to form urate IEA Sus scrofa 17712 R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 17712 R-SSC-9727349 https://reactome.org/PathwayBrowser/#/R-SSC-9727349 XDH dehydrogenates xanthine to form urate IEA Sus scrofa 17712 R-XTR-74247 https://reactome.org/PathwayBrowser/#/R-XTR-74247 XDH oxidizes hypoxanthine to form xanthine IEA Xenopus tropicalis 17712 R-XTR-74255 https://reactome.org/PathwayBrowser/#/R-XTR-74255 Guanine + H2O => Xanthine + NH4+ IEA Xenopus tropicalis 17712 R-XTR-74258 https://reactome.org/PathwayBrowser/#/R-XTR-74258 XDH oxidizes xanthine to form urate IEA Xenopus tropicalis 17712 R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 17712 R-XTR-9727349 https://reactome.org/PathwayBrowser/#/R-XTR-9727349 XDH dehydrogenates xanthine to form urate IEA Xenopus tropicalis 17716 R-BTA-189062 https://reactome.org/PathwayBrowser/#/R-BTA-189062 lactose + H2O => D-glucose + D-galactose IEA Bos taurus 17716 R-BTA-5653878 https://reactome.org/PathwayBrowser/#/R-BTA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Bos taurus 17716 R-CEL-189062 https://reactome.org/PathwayBrowser/#/R-CEL-189062 lactose + H2O => D-glucose + D-galactose IEA Caenorhabditis elegans 17716 R-CFA-189062 https://reactome.org/PathwayBrowser/#/R-CFA-189062 lactose + H2O => D-glucose + D-galactose IEA Canis familiaris 17716 R-CFA-5653878 https://reactome.org/PathwayBrowser/#/R-CFA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Canis familiaris 17716 R-DME-189062 https://reactome.org/PathwayBrowser/#/R-DME-189062 lactose + H2O => D-glucose + D-galactose IEA Drosophila melanogaster 17716 R-DME-5653878 https://reactome.org/PathwayBrowser/#/R-DME-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Drosophila melanogaster 17716 R-DRE-5653878 https://reactome.org/PathwayBrowser/#/R-DRE-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Danio rerio 17716 R-GGA-189062 https://reactome.org/PathwayBrowser/#/R-GGA-189062 lactose + H2O => D-glucose + D-galactose IEA Gallus gallus 17716 R-GGA-5653878 https://reactome.org/PathwayBrowser/#/R-GGA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Gallus gallus 17716 R-HSA-189062 https://reactome.org/PathwayBrowser/#/R-HSA-189062 lactose + H2O => D-glucose + D-galactose TAS Homo sapiens 17716 R-HSA-5653878 https://reactome.org/PathwayBrowser/#/R-HSA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac TAS Homo sapiens 17716 R-HSA-5658001 https://reactome.org/PathwayBrowser/#/R-HSA-5658001 Defective LCT does not hydrolyze Lac TAS Homo sapiens 17716 R-MMU-189062 https://reactome.org/PathwayBrowser/#/R-MMU-189062 lactose + H2O => D-glucose + D-galactose IEA Mus musculus 17716 R-MMU-5653878 https://reactome.org/PathwayBrowser/#/R-MMU-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Mus musculus 17716 R-RNO-189062 https://reactome.org/PathwayBrowser/#/R-RNO-189062 lactose + H2O => D-glucose + D-galactose IEA Rattus norvegicus 17716 R-SSC-189062 https://reactome.org/PathwayBrowser/#/R-SSC-189062 lactose + H2O => D-glucose + D-galactose IEA Sus scrofa 17716 R-SSC-5653878 https://reactome.org/PathwayBrowser/#/R-SSC-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Sus scrofa 17716 R-XTR-189062 https://reactome.org/PathwayBrowser/#/R-XTR-189062 lactose + H2O => D-glucose + D-galactose IEA Xenopus tropicalis 17716 R-XTR-5653878 https://reactome.org/PathwayBrowser/#/R-XTR-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Xenopus tropicalis 17728 R-BTA-5696838 https://reactome.org/PathwayBrowser/#/R-BTA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Bos taurus 17728 R-CFA-5696838 https://reactome.org/PathwayBrowser/#/R-CFA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Canis familiaris 17728 R-DRE-5696838 https://reactome.org/PathwayBrowser/#/R-DRE-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Danio rerio 17728 R-GGA-5696838 https://reactome.org/PathwayBrowser/#/R-GGA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Gallus gallus 17728 R-HSA-5696838 https://reactome.org/PathwayBrowser/#/R-HSA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS TAS Homo sapiens 17728 R-MMU-5696838 https://reactome.org/PathwayBrowser/#/R-MMU-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Mus musculus 17728 R-RNO-5696838 https://reactome.org/PathwayBrowser/#/R-RNO-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Rattus norvegicus 17728 R-SSC-5696838 https://reactome.org/PathwayBrowser/#/R-SSC-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Sus scrofa 17728 R-XTR-5696838 https://reactome.org/PathwayBrowser/#/R-XTR-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Xenopus tropicalis 17732 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 17732 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 17732 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 17732 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 17732 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 17732 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 17732 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 17732 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 17732 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 17732 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 17732 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 17732 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 17732 R-HSA-379864 https://reactome.org/PathwayBrowser/#/R-HSA-379864 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate TAS Homo sapiens 17732 R-HSA-380177 https://reactome.org/PathwayBrowser/#/R-HSA-380177 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate IEA Homo sapiens 17732 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 17732 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 17732 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 17732 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 17732 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 17732 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 17737 R-BTA-196402 https://reactome.org/PathwayBrowser/#/R-BTA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Bos taurus 17737 R-BTA-196417 https://reactome.org/PathwayBrowser/#/R-BTA-196417 Reduction of desmosterol to cholesterol IEA Bos taurus 17737 R-CEL-196402 https://reactome.org/PathwayBrowser/#/R-CEL-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Caenorhabditis elegans 17737 R-CEL-196417 https://reactome.org/PathwayBrowser/#/R-CEL-196417 Reduction of desmosterol to cholesterol IEA Caenorhabditis elegans 17737 R-CFA-196402 https://reactome.org/PathwayBrowser/#/R-CFA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Canis familiaris 17737 R-CFA-196417 https://reactome.org/PathwayBrowser/#/R-CFA-196417 Reduction of desmosterol to cholesterol IEA Canis familiaris 17737 R-DRE-196402 https://reactome.org/PathwayBrowser/#/R-DRE-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Danio rerio 17737 R-DRE-196417 https://reactome.org/PathwayBrowser/#/R-DRE-196417 Reduction of desmosterol to cholesterol IEA Danio rerio 17737 R-GGA-196402 https://reactome.org/PathwayBrowser/#/R-GGA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Gallus gallus 17737 R-GGA-196417 https://reactome.org/PathwayBrowser/#/R-GGA-196417 Reduction of desmosterol to cholesterol IEA Gallus gallus 17737 R-HSA-196402 https://reactome.org/PathwayBrowser/#/R-HSA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol TAS Homo sapiens 17737 R-HSA-196417 https://reactome.org/PathwayBrowser/#/R-HSA-196417 Reduction of desmosterol to cholesterol TAS Homo sapiens 17737 R-MMU-196402 https://reactome.org/PathwayBrowser/#/R-MMU-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Mus musculus 17737 R-MMU-196417 https://reactome.org/PathwayBrowser/#/R-MMU-196417 Reduction of desmosterol to cholesterol IEA Mus musculus 17737 R-RNO-196402 https://reactome.org/PathwayBrowser/#/R-RNO-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Rattus norvegicus 17737 R-RNO-196417 https://reactome.org/PathwayBrowser/#/R-RNO-196417 Reduction of desmosterol to cholesterol IEA Rattus norvegicus 17737 R-SSC-196402 https://reactome.org/PathwayBrowser/#/R-SSC-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Sus scrofa 17737 R-SSC-196417 https://reactome.org/PathwayBrowser/#/R-SSC-196417 Reduction of desmosterol to cholesterol IEA Sus scrofa 17737 R-XTR-196402 https://reactome.org/PathwayBrowser/#/R-XTR-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Xenopus tropicalis 17737 R-XTR-196417 https://reactome.org/PathwayBrowser/#/R-XTR-196417 Reduction of desmosterol to cholesterol IEA Xenopus tropicalis 17742 R-BTA-6784393 https://reactome.org/PathwayBrowser/#/R-BTA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Bos taurus 17742 R-BTA-6784423 https://reactome.org/PathwayBrowser/#/R-BTA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Bos taurus 17742 R-CEL-6784393 https://reactome.org/PathwayBrowser/#/R-CEL-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Caenorhabditis elegans 17742 R-CFA-6784393 https://reactome.org/PathwayBrowser/#/R-CFA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Canis familiaris 17742 R-CFA-6784423 https://reactome.org/PathwayBrowser/#/R-CFA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Canis familiaris 17742 R-DDI-6784393 https://reactome.org/PathwayBrowser/#/R-DDI-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Dictyostelium discoideum 17742 R-DME-6784393 https://reactome.org/PathwayBrowser/#/R-DME-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Drosophila melanogaster 17742 R-DRE-6784393 https://reactome.org/PathwayBrowser/#/R-DRE-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Danio rerio 17742 R-DRE-6784423 https://reactome.org/PathwayBrowser/#/R-DRE-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Danio rerio 17742 R-GGA-6784393 https://reactome.org/PathwayBrowser/#/R-GGA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Gallus gallus 17742 R-GGA-6784423 https://reactome.org/PathwayBrowser/#/R-GGA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Gallus gallus 17742 R-HSA-6784393 https://reactome.org/PathwayBrowser/#/R-HSA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) TAS Homo sapiens 17742 R-HSA-6784423 https://reactome.org/PathwayBrowser/#/R-HSA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate TAS Homo sapiens 17742 R-MMU-6784393 https://reactome.org/PathwayBrowser/#/R-MMU-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Mus musculus 17742 R-MMU-6784423 https://reactome.org/PathwayBrowser/#/R-MMU-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Mus musculus 17742 R-RNO-6784393 https://reactome.org/PathwayBrowser/#/R-RNO-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Rattus norvegicus 17742 R-RNO-6784423 https://reactome.org/PathwayBrowser/#/R-RNO-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Rattus norvegicus 17742 R-SCE-6784393 https://reactome.org/PathwayBrowser/#/R-SCE-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Saccharomyces cerevisiae 17742 R-SPO-6784393 https://reactome.org/PathwayBrowser/#/R-SPO-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Schizosaccharomyces pombe 17742 R-SSC-6784393 https://reactome.org/PathwayBrowser/#/R-SSC-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Sus scrofa 17742 R-SSC-6784423 https://reactome.org/PathwayBrowser/#/R-SSC-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Sus scrofa 17742 R-XTR-6784393 https://reactome.org/PathwayBrowser/#/R-XTR-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Xenopus tropicalis 17742 R-XTR-6784423 https://reactome.org/PathwayBrowser/#/R-XTR-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Xenopus tropicalis 17748 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 17748 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 17748 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 17748 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 17748 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 17748 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17748 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17748 R-BTA-109530 https://reactome.org/PathwayBrowser/#/R-BTA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Bos taurus 17748 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 17748 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 17748 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 17748 R-BTA-109759 https://reactome.org/PathwayBrowser/#/R-BTA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Bos taurus 17748 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 17748 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 17748 R-BTA-73632 https://reactome.org/PathwayBrowser/#/R-BTA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Bos taurus 17748 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 17748 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17748 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17748 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans 17748 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 17748 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 17748 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 17748 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 17748 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 17748 R-CEL-73632 https://reactome.org/PathwayBrowser/#/R-CEL-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Caenorhabditis elegans 17748 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 17748 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 17748 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 17748 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 17748 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 17748 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17748 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17748 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 17748 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 17748 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 17748 R-CFA-109759 https://reactome.org/PathwayBrowser/#/R-CFA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Canis familiaris 17748 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 17748 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 17748 R-CFA-73632 https://reactome.org/PathwayBrowser/#/R-CFA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Canis familiaris 17748 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17748 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17748 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 17748 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 17748 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 17748 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 17748 R-DDI-73632 https://reactome.org/PathwayBrowser/#/R-DDI-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Dictyostelium discoideum 17748 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 17748 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 17748 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17748 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17748 R-DME-109530 https://reactome.org/PathwayBrowser/#/R-DME-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Drosophila melanogaster 17748 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 17748 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 17748 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 17748 R-DME-109759 https://reactome.org/PathwayBrowser/#/R-DME-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Drosophila melanogaster 17748 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 17748 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 17748 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 17748 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 17748 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 17748 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 17748 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 17748 R-DRE-73632 https://reactome.org/PathwayBrowser/#/R-DRE-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Danio rerio 17748 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 17748 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 17748 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 17748 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 17748 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 17748 R-GGA-109759 https://reactome.org/PathwayBrowser/#/R-GGA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Gallus gallus 17748 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 17748 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 17748 R-GGA-73632 https://reactome.org/PathwayBrowser/#/R-GGA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Gallus gallus 17748 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 17748 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 17748 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 17748 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 17748 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 17748 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17748 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17748 R-HSA-109530 https://reactome.org/PathwayBrowser/#/R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 TAS Homo sapiens 17748 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 17748 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 17748 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 17748 R-HSA-109759 https://reactome.org/PathwayBrowser/#/R-HSA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] TAS Homo sapiens 17748 R-HSA-112265 https://reactome.org/PathwayBrowser/#/R-HSA-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] TAS Homo sapiens 17748 R-HSA-112266 https://reactome.org/PathwayBrowser/#/R-HSA-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] TAS Homo sapiens 17748 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 17748 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 17748 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 17748 R-HSA-73632 https://reactome.org/PathwayBrowser/#/R-HSA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] TAS Homo sapiens 17748 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 17748 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 17748 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 17748 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 17748 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 17748 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17748 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17748 R-MMU-109530 https://reactome.org/PathwayBrowser/#/R-MMU-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Mus musculus 17748 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 17748 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 17748 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 17748 R-MMU-109759 https://reactome.org/PathwayBrowser/#/R-MMU-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Mus musculus 17748 R-MMU-112265 https://reactome.org/PathwayBrowser/#/R-MMU-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Mus musculus 17748 R-MMU-112266 https://reactome.org/PathwayBrowser/#/R-MMU-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Mus musculus 17748 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 17748 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 17748 R-MMU-73632 https://reactome.org/PathwayBrowser/#/R-MMU-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Mus musculus 17748 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17748 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17748 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 17748 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 17748 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 17748 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 17748 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 17748 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 17748 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 17748 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 17748 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 17748 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17748 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17748 R-RNO-109530 https://reactome.org/PathwayBrowser/#/R-RNO-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Rattus norvegicus 17748 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 17748 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 17748 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 17748 R-RNO-109759 https://reactome.org/PathwayBrowser/#/R-RNO-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Rattus norvegicus 17748 R-RNO-112265 https://reactome.org/PathwayBrowser/#/R-RNO-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Rattus norvegicus 17748 R-RNO-112266 https://reactome.org/PathwayBrowser/#/R-RNO-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Rattus norvegicus 17748 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 17748 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 17748 R-RNO-73632 https://reactome.org/PathwayBrowser/#/R-RNO-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Rattus norvegicus 17748 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 17748 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 17748 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 17748 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 17748 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 17748 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17748 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17748 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa 17748 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 17748 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 17748 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 17748 R-SSC-109759 https://reactome.org/PathwayBrowser/#/R-SSC-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Sus scrofa 17748 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 17748 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 17748 R-SSC-73632 https://reactome.org/PathwayBrowser/#/R-SSC-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Sus scrofa 17748 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 17748 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 17748 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 17748 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 17748 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 17748 R-XTR-109530 https://reactome.org/PathwayBrowser/#/R-XTR-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Xenopus tropicalis 17748 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 17748 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 17748 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 17748 R-XTR-109759 https://reactome.org/PathwayBrowser/#/R-XTR-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Xenopus tropicalis 17748 R-XTR-112265 https://reactome.org/PathwayBrowser/#/R-XTR-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Xenopus tropicalis 17748 R-XTR-112266 https://reactome.org/PathwayBrowser/#/R-XTR-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Xenopus tropicalis 17748 R-XTR-73632 https://reactome.org/PathwayBrowser/#/R-XTR-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Xenopus tropicalis 17750 R-BTA-1614654 https://reactome.org/PathwayBrowser/#/R-BTA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Bos taurus 17750 R-BTA-352029 https://reactome.org/PathwayBrowser/#/R-BTA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Bos taurus 17750 R-BTA-6797955 https://reactome.org/PathwayBrowser/#/R-BTA-6797955 ALDH7A1 oxidises BETALD to BET IEA Bos taurus 17750 R-CEL-6797955 https://reactome.org/PathwayBrowser/#/R-CEL-6797955 ALDH7A1 oxidises BETALD to BET IEA Caenorhabditis elegans 17750 R-CFA-1614654 https://reactome.org/PathwayBrowser/#/R-CFA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Canis familiaris 17750 R-CFA-352029 https://reactome.org/PathwayBrowser/#/R-CFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Canis familiaris 17750 R-CFA-6797955 https://reactome.org/PathwayBrowser/#/R-CFA-6797955 ALDH7A1 oxidises BETALD to BET IEA Canis familiaris 17750 R-DDI-6797955 https://reactome.org/PathwayBrowser/#/R-DDI-6797955 ALDH7A1 oxidises BETALD to BET IEA Dictyostelium discoideum 17750 R-DME-6797955 https://reactome.org/PathwayBrowser/#/R-DME-6797955 ALDH7A1 oxidises BETALD to BET IEA Drosophila melanogaster 17750 R-DRE-1614654 https://reactome.org/PathwayBrowser/#/R-DRE-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Danio rerio 17750 R-DRE-352029 https://reactome.org/PathwayBrowser/#/R-DRE-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Danio rerio 17750 R-DRE-6797955 https://reactome.org/PathwayBrowser/#/R-DRE-6797955 ALDH7A1 oxidises BETALD to BET IEA Danio rerio 17750 R-GGA-1614654 https://reactome.org/PathwayBrowser/#/R-GGA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Gallus gallus 17750 R-GGA-352029 https://reactome.org/PathwayBrowser/#/R-GGA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Gallus gallus 17750 R-GGA-6797955 https://reactome.org/PathwayBrowser/#/R-GGA-6797955 ALDH7A1 oxidises BETALD to BET IEA Gallus gallus 17750 R-HSA-1614654 https://reactome.org/PathwayBrowser/#/R-HSA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY TAS Homo sapiens 17750 R-HSA-352029 https://reactome.org/PathwayBrowser/#/R-HSA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine TAS Homo sapiens 17750 R-HSA-6797955 https://reactome.org/PathwayBrowser/#/R-HSA-6797955 ALDH7A1 oxidises BETALD to BET TAS Homo sapiens 17750 R-HSA-6797957 https://reactome.org/PathwayBrowser/#/R-HSA-6797957 BET translocates from mitochondrial matrix to cytosol TAS Homo sapiens 17750 R-MMU-1614654 https://reactome.org/PathwayBrowser/#/R-MMU-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Mus musculus 17750 R-MMU-352029 https://reactome.org/PathwayBrowser/#/R-MMU-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Mus musculus 17750 R-MMU-6797955 https://reactome.org/PathwayBrowser/#/R-MMU-6797955 ALDH7A1 oxidises BETALD to BET IEA Mus musculus 17750 R-PFA-352029 https://reactome.org/PathwayBrowser/#/R-PFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Plasmodium falciparum 17750 R-RNO-1614654 https://reactome.org/PathwayBrowser/#/R-RNO-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Rattus norvegicus 17750 R-RNO-352029 https://reactome.org/PathwayBrowser/#/R-RNO-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Rattus norvegicus 17750 R-RNO-6797955 https://reactome.org/PathwayBrowser/#/R-RNO-6797955 ALDH7A1 oxidises BETALD to BET IEA Rattus norvegicus 17750 R-SSC-1614654 https://reactome.org/PathwayBrowser/#/R-SSC-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Sus scrofa 17750 R-SSC-352029 https://reactome.org/PathwayBrowser/#/R-SSC-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Sus scrofa 17750 R-SSC-6797955 https://reactome.org/PathwayBrowser/#/R-SSC-6797955 ALDH7A1 oxidises BETALD to BET IEA Sus scrofa 17750 R-XTR-1614654 https://reactome.org/PathwayBrowser/#/R-XTR-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Xenopus tropicalis 17750 R-XTR-352029 https://reactome.org/PathwayBrowser/#/R-XTR-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Xenopus tropicalis 17750 R-XTR-6797955 https://reactome.org/PathwayBrowser/#/R-XTR-6797955 ALDH7A1 oxidises BETALD to BET IEA Xenopus tropicalis 17754 R-BTA-1482543 https://reactome.org/PathwayBrowser/#/R-BTA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Bos taurus 17754 R-BTA-1482647 https://reactome.org/PathwayBrowser/#/R-BTA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Bos taurus 17754 R-BTA-1482654 https://reactome.org/PathwayBrowser/#/R-BTA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Bos taurus 17754 R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 17754 R-BTA-426043 https://reactome.org/PathwayBrowser/#/R-BTA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Bos taurus 17754 R-BTA-432049 https://reactome.org/PathwayBrowser/#/R-BTA-432049 Aquaporin-9 passively transports glycerol into cell IEA Bos taurus 17754 R-BTA-432074 https://reactome.org/PathwayBrowser/#/R-BTA-432074 Aquaporin-7 passively transports glycerol out of cell IEA Bos taurus 17754 R-BTA-507869 https://reactome.org/PathwayBrowser/#/R-BTA-507869 Aquaporins passively transport glycerol into cells IEA Bos taurus 17754 R-BTA-507871 https://reactome.org/PathwayBrowser/#/R-BTA-507871 Aquaporins passively transport glycerol out of cells IEA Bos taurus 17754 R-BTA-5694462 https://reactome.org/PathwayBrowser/#/R-BTA-5694462 ABHD6,12 hydrolyse 3AG IEA Bos taurus 17754 R-BTA-5696119 https://reactome.org/PathwayBrowser/#/R-BTA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Bos taurus 17754 R-BTA-75887 https://reactome.org/PathwayBrowser/#/R-BTA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Bos taurus 17754 R-CEL-1482647 https://reactome.org/PathwayBrowser/#/R-CEL-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Caenorhabditis elegans 17754 R-CEL-1482654 https://reactome.org/PathwayBrowser/#/R-CEL-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Caenorhabditis elegans 17754 R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 17754 R-CEL-432049 https://reactome.org/PathwayBrowser/#/R-CEL-432049 Aquaporin-9 passively transports glycerol into cell IEA Caenorhabditis elegans 17754 R-CEL-432074 https://reactome.org/PathwayBrowser/#/R-CEL-432074 Aquaporin-7 passively transports glycerol out of cell IEA Caenorhabditis elegans 17754 R-CEL-507869 https://reactome.org/PathwayBrowser/#/R-CEL-507869 Aquaporins passively transport glycerol into cells IEA Caenorhabditis elegans 17754 R-CEL-507871 https://reactome.org/PathwayBrowser/#/R-CEL-507871 Aquaporins passively transport glycerol out of cells IEA Caenorhabditis elegans 17754 R-CEL-5694462 https://reactome.org/PathwayBrowser/#/R-CEL-5694462 ABHD6,12 hydrolyse 3AG IEA Caenorhabditis elegans 17754 R-CEL-5696119 https://reactome.org/PathwayBrowser/#/R-CEL-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Caenorhabditis elegans 17754 R-CEL-75887 https://reactome.org/PathwayBrowser/#/R-CEL-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Caenorhabditis elegans 17754 R-CFA-1482543 https://reactome.org/PathwayBrowser/#/R-CFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Canis familiaris 17754 R-CFA-1482647 https://reactome.org/PathwayBrowser/#/R-CFA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Canis familiaris 17754 R-CFA-1482654 https://reactome.org/PathwayBrowser/#/R-CFA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Canis familiaris 17754 R-CFA-426043 https://reactome.org/PathwayBrowser/#/R-CFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Canis familiaris 17754 R-CFA-432049 https://reactome.org/PathwayBrowser/#/R-CFA-432049 Aquaporin-9 passively transports glycerol into cell IEA Canis familiaris 17754 R-CFA-432074 https://reactome.org/PathwayBrowser/#/R-CFA-432074 Aquaporin-7 passively transports glycerol out of cell IEA Canis familiaris 17754 R-CFA-507869 https://reactome.org/PathwayBrowser/#/R-CFA-507869 Aquaporins passively transport glycerol into cells IEA Canis familiaris 17754 R-CFA-507871 https://reactome.org/PathwayBrowser/#/R-CFA-507871 Aquaporins passively transport glycerol out of cells IEA Canis familiaris 17754 R-CFA-5694462 https://reactome.org/PathwayBrowser/#/R-CFA-5694462 ABHD6,12 hydrolyse 3AG IEA Canis familiaris 17754 R-CFA-5696119 https://reactome.org/PathwayBrowser/#/R-CFA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Canis familiaris 17754 R-CFA-75887 https://reactome.org/PathwayBrowser/#/R-CFA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Canis familiaris 17754 R-DDI-1482543 https://reactome.org/PathwayBrowser/#/R-DDI-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Dictyostelium discoideum 17754 R-DDI-426043 https://reactome.org/PathwayBrowser/#/R-DDI-426043 2-AG hydrolysis to arachidonate by MAGL IEA Dictyostelium discoideum 17754 R-DDI-5696119 https://reactome.org/PathwayBrowser/#/R-DDI-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Dictyostelium discoideum 17754 R-DDI-75887 https://reactome.org/PathwayBrowser/#/R-DDI-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Dictyostelium discoideum 17754 R-DME-1482647 https://reactome.org/PathwayBrowser/#/R-DME-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Drosophila melanogaster 17754 R-DME-1482654 https://reactome.org/PathwayBrowser/#/R-DME-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Drosophila melanogaster 17754 R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 17754 R-DME-5694462 https://reactome.org/PathwayBrowser/#/R-DME-5694462 ABHD6,12 hydrolyse 3AG IEA Drosophila melanogaster 17754 R-DME-75887 https://reactome.org/PathwayBrowser/#/R-DME-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Drosophila melanogaster 17754 R-DRE-1482543 https://reactome.org/PathwayBrowser/#/R-DRE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Danio rerio 17754 R-DRE-1482647 https://reactome.org/PathwayBrowser/#/R-DRE-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Danio rerio 17754 R-DRE-1482654 https://reactome.org/PathwayBrowser/#/R-DRE-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Danio rerio 17754 R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 17754 R-DRE-426043 https://reactome.org/PathwayBrowser/#/R-DRE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Danio rerio 17754 R-DRE-432049 https://reactome.org/PathwayBrowser/#/R-DRE-432049 Aquaporin-9 passively transports glycerol into cell IEA Danio rerio 17754 R-DRE-507869 https://reactome.org/PathwayBrowser/#/R-DRE-507869 Aquaporins passively transport glycerol into cells IEA Danio rerio 17754 R-DRE-507871 https://reactome.org/PathwayBrowser/#/R-DRE-507871 Aquaporins passively transport glycerol out of cells IEA Danio rerio 17754 R-DRE-5694462 https://reactome.org/PathwayBrowser/#/R-DRE-5694462 ABHD6,12 hydrolyse 3AG IEA Danio rerio 17754 R-DRE-5696119 https://reactome.org/PathwayBrowser/#/R-DRE-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Danio rerio 17754 R-GGA-1482543 https://reactome.org/PathwayBrowser/#/R-GGA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Gallus gallus 17754 R-GGA-1482647 https://reactome.org/PathwayBrowser/#/R-GGA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Gallus gallus 17754 R-GGA-1482654 https://reactome.org/PathwayBrowser/#/R-GGA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Gallus gallus 17754 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 17754 R-GGA-426043 https://reactome.org/PathwayBrowser/#/R-GGA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Gallus gallus 17754 R-GGA-432049 https://reactome.org/PathwayBrowser/#/R-GGA-432049 Aquaporin-9 passively transports glycerol into cell IEA Gallus gallus 17754 R-GGA-432074 https://reactome.org/PathwayBrowser/#/R-GGA-432074 Aquaporin-7 passively transports glycerol out of cell IEA Gallus gallus 17754 R-GGA-507869 https://reactome.org/PathwayBrowser/#/R-GGA-507869 Aquaporins passively transport glycerol into cells IEA Gallus gallus 17754 R-GGA-507871 https://reactome.org/PathwayBrowser/#/R-GGA-507871 Aquaporins passively transport glycerol out of cells IEA Gallus gallus 17754 R-GGA-5694462 https://reactome.org/PathwayBrowser/#/R-GGA-5694462 ABHD6,12 hydrolyse 3AG IEA Gallus gallus 17754 R-GGA-5696119 https://reactome.org/PathwayBrowser/#/R-GGA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Gallus gallus 17754 R-GGA-75887 https://reactome.org/PathwayBrowser/#/R-GGA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Gallus gallus 17754 R-HSA-1482543 https://reactome.org/PathwayBrowser/#/R-HSA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL TAS Homo sapiens 17754 R-HSA-1482647 https://reactome.org/PathwayBrowser/#/R-HSA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 TAS Homo sapiens 17754 R-HSA-1482654 https://reactome.org/PathwayBrowser/#/R-HSA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 TAS Homo sapiens 17754 R-HSA-1483142 https://reactome.org/PathwayBrowser/#/R-HSA-1483142 PC is transphosphatidylated to PG by PLD1-4/6 IEA Homo sapiens 17754 R-HSA-163595 https://reactome.org/PathwayBrowser/#/R-HSA-163595 2-acylglycerol + H2O -> glycerol + fatty acid IEA Homo sapiens 17754 R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 17754 R-HSA-426043 https://reactome.org/PathwayBrowser/#/R-HSA-426043 2-AG hydrolysis to arachidonate by MAGL TAS Homo sapiens 17754 R-HSA-432049 https://reactome.org/PathwayBrowser/#/R-HSA-432049 Aquaporin-9 passively transports glycerol into cell TAS Homo sapiens 17754 R-HSA-432074 https://reactome.org/PathwayBrowser/#/R-HSA-432074 Aquaporin-7 passively transports glycerol out of cell TAS Homo sapiens 17754 R-HSA-507869 https://reactome.org/PathwayBrowser/#/R-HSA-507869 Aquaporins passively transport glycerol into cells TAS Homo sapiens 17754 R-HSA-507871 https://reactome.org/PathwayBrowser/#/R-HSA-507871 Aquaporins passively transport glycerol out of cells TAS Homo sapiens 17754 R-HSA-5694462 https://reactome.org/PathwayBrowser/#/R-HSA-5694462 ABHD6,12 hydrolyse 3AG TAS Homo sapiens 17754 R-HSA-5696119 https://reactome.org/PathwayBrowser/#/R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol TAS Homo sapiens 17754 R-HSA-75887 https://reactome.org/PathwayBrowser/#/R-HSA-75887 Conversion of Glycerol to Glycerol-3-phosphate TAS Homo sapiens 17754 R-HSA-8955794 https://reactome.org/PathwayBrowser/#/R-HSA-8955794 PGP:Mg2+ dimer hydrolyses 3PG to glycerol IEA Homo sapiens 17754 R-MMU-1482543 https://reactome.org/PathwayBrowser/#/R-MMU-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Mus musculus 17754 R-MMU-1482647 https://reactome.org/PathwayBrowser/#/R-MMU-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Mus musculus 17754 R-MMU-1482654 https://reactome.org/PathwayBrowser/#/R-MMU-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Mus musculus 17754 R-MMU-1483172 https://reactome.org/PathwayBrowser/#/R-MMU-1483172 PC is transphosphatidylated to PG by Pld1-4/6 TAS Mus musculus 17754 R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 17754 R-MMU-426043 https://reactome.org/PathwayBrowser/#/R-MMU-426043 2-AG hydrolysis to arachidonate by MAGL IEA Mus musculus 17754 R-MMU-432049 https://reactome.org/PathwayBrowser/#/R-MMU-432049 Aquaporin-9 passively transports glycerol into cell IEA Mus musculus 17754 R-MMU-432074 https://reactome.org/PathwayBrowser/#/R-MMU-432074 Aquaporin-7 passively transports glycerol out of cell IEA Mus musculus 17754 R-MMU-507869 https://reactome.org/PathwayBrowser/#/R-MMU-507869 Aquaporins passively transport glycerol into cells IEA Mus musculus 17754 R-MMU-507871 https://reactome.org/PathwayBrowser/#/R-MMU-507871 Aquaporins passively transport glycerol out of cells IEA Mus musculus 17754 R-MMU-5694462 https://reactome.org/PathwayBrowser/#/R-MMU-5694462 ABHD6,12 hydrolyse 3AG IEA Mus musculus 17754 R-MMU-5696119 https://reactome.org/PathwayBrowser/#/R-MMU-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Mus musculus 17754 R-MMU-75887 https://reactome.org/PathwayBrowser/#/R-MMU-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Mus musculus 17754 R-PFA-1482543 https://reactome.org/PathwayBrowser/#/R-PFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Plasmodium falciparum 17754 R-PFA-1482647 https://reactome.org/PathwayBrowser/#/R-PFA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Plasmodium falciparum 17754 R-PFA-1482654 https://reactome.org/PathwayBrowser/#/R-PFA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Plasmodium falciparum 17754 R-PFA-426043 https://reactome.org/PathwayBrowser/#/R-PFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Plasmodium falciparum 17754 R-PFA-432049 https://reactome.org/PathwayBrowser/#/R-PFA-432049 Aquaporin-9 passively transports glycerol into cell IEA Plasmodium falciparum 17754 R-PFA-432074 https://reactome.org/PathwayBrowser/#/R-PFA-432074 Aquaporin-7 passively transports glycerol out of cell IEA Plasmodium falciparum 17754 R-PFA-507869 https://reactome.org/PathwayBrowser/#/R-PFA-507869 Aquaporins passively transport glycerol into cells IEA Plasmodium falciparum 17754 R-PFA-507871 https://reactome.org/PathwayBrowser/#/R-PFA-507871 Aquaporins passively transport glycerol out of cells IEA Plasmodium falciparum 17754 R-PFA-75887 https://reactome.org/PathwayBrowser/#/R-PFA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Plasmodium falciparum 17754 R-RNO-1482543 https://reactome.org/PathwayBrowser/#/R-RNO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Rattus norvegicus 17754 R-RNO-1482647 https://reactome.org/PathwayBrowser/#/R-RNO-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Rattus norvegicus 17754 R-RNO-1482654 https://reactome.org/PathwayBrowser/#/R-RNO-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Rattus norvegicus 17754 R-RNO-163439 https://reactome.org/PathwayBrowser/#/R-RNO-163439 2-acylglycerol + H2O -> glycerol + fatty acid TAS Rattus norvegicus 17754 R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 17754 R-RNO-426043 https://reactome.org/PathwayBrowser/#/R-RNO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Rattus norvegicus 17754 R-RNO-432049 https://reactome.org/PathwayBrowser/#/R-RNO-432049 Aquaporin-9 passively transports glycerol into cell IEA Rattus norvegicus 17754 R-RNO-432074 https://reactome.org/PathwayBrowser/#/R-RNO-432074 Aquaporin-7 passively transports glycerol out of cell IEA Rattus norvegicus 17754 R-RNO-507869 https://reactome.org/PathwayBrowser/#/R-RNO-507869 Aquaporins passively transport glycerol into cells IEA Rattus norvegicus 17754 R-RNO-507871 https://reactome.org/PathwayBrowser/#/R-RNO-507871 Aquaporins passively transport glycerol out of cells IEA Rattus norvegicus 17754 R-RNO-5694462 https://reactome.org/PathwayBrowser/#/R-RNO-5694462 ABHD6,12 hydrolyse 3AG IEA Rattus norvegicus 17754 R-RNO-5696119 https://reactome.org/PathwayBrowser/#/R-RNO-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Rattus norvegicus 17754 R-RNO-75887 https://reactome.org/PathwayBrowser/#/R-RNO-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Rattus norvegicus 17754 R-RNO-8955775 https://reactome.org/PathwayBrowser/#/R-RNO-8955775 Pgp:Mg2+ dimer hydrolyses 3PG to glycerol TAS Rattus norvegicus 17754 R-SCE-1482543 https://reactome.org/PathwayBrowser/#/R-SCE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Saccharomyces cerevisiae 17754 R-SCE-426043 https://reactome.org/PathwayBrowser/#/R-SCE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Saccharomyces cerevisiae 17754 R-SCE-432049 https://reactome.org/PathwayBrowser/#/R-SCE-432049 Aquaporin-9 passively transports glycerol into cell IEA Saccharomyces cerevisiae 17754 R-SCE-432074 https://reactome.org/PathwayBrowser/#/R-SCE-432074 Aquaporin-7 passively transports glycerol out of cell IEA Saccharomyces cerevisiae 17754 R-SCE-507869 https://reactome.org/PathwayBrowser/#/R-SCE-507869 Aquaporins passively transport glycerol into cells IEA Saccharomyces cerevisiae 17754 R-SCE-507871 https://reactome.org/PathwayBrowser/#/R-SCE-507871 Aquaporins passively transport glycerol out of cells IEA Saccharomyces cerevisiae 17754 R-SCE-5694462 https://reactome.org/PathwayBrowser/#/R-SCE-5694462 ABHD6,12 hydrolyse 3AG IEA Saccharomyces cerevisiae 17754 R-SCE-75887 https://reactome.org/PathwayBrowser/#/R-SCE-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Saccharomyces cerevisiae 17754 R-SPO-1482543 https://reactome.org/PathwayBrowser/#/R-SPO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Schizosaccharomyces pombe 17754 R-SPO-426043 https://reactome.org/PathwayBrowser/#/R-SPO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Schizosaccharomyces pombe 17754 R-SPO-432049 https://reactome.org/PathwayBrowser/#/R-SPO-432049 Aquaporin-9 passively transports glycerol into cell IEA Schizosaccharomyces pombe 17754 R-SPO-432074 https://reactome.org/PathwayBrowser/#/R-SPO-432074 Aquaporin-7 passively transports glycerol out of cell IEA Schizosaccharomyces pombe 17754 R-SPO-507869 https://reactome.org/PathwayBrowser/#/R-SPO-507869 Aquaporins passively transport glycerol into cells IEA Schizosaccharomyces pombe 17754 R-SPO-507871 https://reactome.org/PathwayBrowser/#/R-SPO-507871 Aquaporins passively transport glycerol out of cells IEA Schizosaccharomyces pombe 17754 R-SSC-1482543 https://reactome.org/PathwayBrowser/#/R-SSC-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Sus scrofa 17754 R-SSC-1482647 https://reactome.org/PathwayBrowser/#/R-SSC-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Sus scrofa 17754 R-SSC-1482654 https://reactome.org/PathwayBrowser/#/R-SSC-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Sus scrofa 17754 R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 17754 R-SSC-426043 https://reactome.org/PathwayBrowser/#/R-SSC-426043 2-AG hydrolysis to arachidonate by MAGL IEA Sus scrofa 17754 R-SSC-432049 https://reactome.org/PathwayBrowser/#/R-SSC-432049 Aquaporin-9 passively transports glycerol into cell IEA Sus scrofa 17754 R-SSC-432074 https://reactome.org/PathwayBrowser/#/R-SSC-432074 Aquaporin-7 passively transports glycerol out of cell IEA Sus scrofa 17754 R-SSC-507869 https://reactome.org/PathwayBrowser/#/R-SSC-507869 Aquaporins passively transport glycerol into cells IEA Sus scrofa 17754 R-SSC-507871 https://reactome.org/PathwayBrowser/#/R-SSC-507871 Aquaporins passively transport glycerol out of cells IEA Sus scrofa 17754 R-SSC-5694462 https://reactome.org/PathwayBrowser/#/R-SSC-5694462 ABHD6,12 hydrolyse 3AG IEA Sus scrofa 17754 R-SSC-5696119 https://reactome.org/PathwayBrowser/#/R-SSC-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Sus scrofa 17754 R-SSC-75887 https://reactome.org/PathwayBrowser/#/R-SSC-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Sus scrofa 17754 R-XTR-1482543 https://reactome.org/PathwayBrowser/#/R-XTR-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Xenopus tropicalis 17754 R-XTR-1482647 https://reactome.org/PathwayBrowser/#/R-XTR-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Xenopus tropicalis 17754 R-XTR-1482654 https://reactome.org/PathwayBrowser/#/R-XTR-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Xenopus tropicalis 17754 R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 17754 R-XTR-426043 https://reactome.org/PathwayBrowser/#/R-XTR-426043 2-AG hydrolysis to arachidonate by MAGL IEA Xenopus tropicalis 17754 R-XTR-432049 https://reactome.org/PathwayBrowser/#/R-XTR-432049 Aquaporin-9 passively transports glycerol into cell IEA Xenopus tropicalis 17754 R-XTR-432074 https://reactome.org/PathwayBrowser/#/R-XTR-432074 Aquaporin-7 passively transports glycerol out of cell IEA Xenopus tropicalis 17754 R-XTR-507869 https://reactome.org/PathwayBrowser/#/R-XTR-507869 Aquaporins passively transport glycerol into cells IEA Xenopus tropicalis 17754 R-XTR-507871 https://reactome.org/PathwayBrowser/#/R-XTR-507871 Aquaporins passively transport glycerol out of cells IEA Xenopus tropicalis 17754 R-XTR-5694462 https://reactome.org/PathwayBrowser/#/R-XTR-5694462 ABHD6,12 hydrolyse 3AG IEA Xenopus tropicalis 17754 R-XTR-5696119 https://reactome.org/PathwayBrowser/#/R-XTR-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Xenopus tropicalis 17754 R-XTR-75887 https://reactome.org/PathwayBrowser/#/R-XTR-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Xenopus tropicalis 17755 R-MTU-937192 https://reactome.org/PathwayBrowser/#/R-MTU-937192 Cysteine from cystathionine and vice versa TAS Mycobacterium tuberculosis 17759 R-BTA-6807053 https://reactome.org/PathwayBrowser/#/R-BTA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Bos taurus 17759 R-BTA-6807055 https://reactome.org/PathwayBrowser/#/R-BTA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Bos taurus 17759 R-CEL-6807055 https://reactome.org/PathwayBrowser/#/R-CEL-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Caenorhabditis elegans 17759 R-CFA-6807053 https://reactome.org/PathwayBrowser/#/R-CFA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Canis familiaris 17759 R-CFA-6807055 https://reactome.org/PathwayBrowser/#/R-CFA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Canis familiaris 17759 R-DRE-6807053 https://reactome.org/PathwayBrowser/#/R-DRE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Danio rerio 17759 R-DRE-6807055 https://reactome.org/PathwayBrowser/#/R-DRE-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Danio rerio 17759 R-GGA-6807053 https://reactome.org/PathwayBrowser/#/R-GGA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Gallus gallus 17759 R-GGA-6807055 https://reactome.org/PathwayBrowser/#/R-GGA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Gallus gallus 17759 R-HSA-209754 https://reactome.org/PathwayBrowser/#/R-HSA-209754 Photolytic cleavage and thermal isomerization of 7-dehydroCHOL IEA Homo sapiens 17759 R-HSA-6807053 https://reactome.org/PathwayBrowser/#/R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL TAS Homo sapiens 17759 R-HSA-6807055 https://reactome.org/PathwayBrowser/#/R-HSA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL TAS Homo sapiens 17759 R-MMU-6807053 https://reactome.org/PathwayBrowser/#/R-MMU-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Mus musculus 17759 R-MMU-6807055 https://reactome.org/PathwayBrowser/#/R-MMU-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Mus musculus 17759 R-RNO-209770 https://reactome.org/PathwayBrowser/#/R-RNO-209770 Photolytic cleavage and thermal isomerization of 7-dehydrocholesterol TAS Rattus norvegicus 17759 R-RNO-6807053 https://reactome.org/PathwayBrowser/#/R-RNO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Rattus norvegicus 17759 R-RNO-6807055 https://reactome.org/PathwayBrowser/#/R-RNO-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Rattus norvegicus 17759 R-SCE-6807053 https://reactome.org/PathwayBrowser/#/R-SCE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Saccharomyces cerevisiae 17759 R-SPO-6807053 https://reactome.org/PathwayBrowser/#/R-SPO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Schizosaccharomyces pombe 17759 R-SSC-6807053 https://reactome.org/PathwayBrowser/#/R-SSC-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Sus scrofa 17759 R-SSC-6807055 https://reactome.org/PathwayBrowser/#/R-SSC-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Sus scrofa 17759 R-XTR-6807053 https://reactome.org/PathwayBrowser/#/R-XTR-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Xenopus tropicalis 17759 R-XTR-6807055 https://reactome.org/PathwayBrowser/#/R-XTR-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Xenopus tropicalis 17761 R-BTA-6810937 https://reactome.org/PathwayBrowser/#/R-BTA-6810937 Lamellar bodies bind the early cornified envelope IEA Bos taurus 17761 R-BTA-6814387 https://reactome.org/PathwayBrowser/#/R-BTA-6814387 CASP14 cleaves filaggrin IEA Bos taurus 17761 R-BTA-6814734 https://reactome.org/PathwayBrowser/#/R-BTA-6814734 CDSN binds the cornified envelope IEA Bos taurus 17761 R-BTA-6814764 https://reactome.org/PathwayBrowser/#/R-BTA-6814764 Plasma membrane resorption IEA Bos taurus 17761 R-CFA-6810937 https://reactome.org/PathwayBrowser/#/R-CFA-6810937 Lamellar bodies bind the early cornified envelope IEA Canis familiaris 17761 R-CFA-6814387 https://reactome.org/PathwayBrowser/#/R-CFA-6814387 CASP14 cleaves filaggrin IEA Canis familiaris 17761 R-CFA-6814734 https://reactome.org/PathwayBrowser/#/R-CFA-6814734 CDSN binds the cornified envelope IEA Canis familiaris 17761 R-CFA-6814764 https://reactome.org/PathwayBrowser/#/R-CFA-6814764 Plasma membrane resorption IEA Canis familiaris 17761 R-HSA-6810937 https://reactome.org/PathwayBrowser/#/R-HSA-6810937 Lamellar bodies bind the early cornified envelope TAS Homo sapiens 17761 R-HSA-6814298 https://reactome.org/PathwayBrowser/#/R-HSA-6814298 Late envelope proteins bind cornified envelope:CDSN TAS Homo sapiens 17761 R-HSA-6814387 https://reactome.org/PathwayBrowser/#/R-HSA-6814387 CASP14 cleaves filaggrin TAS Homo sapiens 17761 R-HSA-6814734 https://reactome.org/PathwayBrowser/#/R-HSA-6814734 CDSN binds the cornified envelope TAS Homo sapiens 17761 R-HSA-6814764 https://reactome.org/PathwayBrowser/#/R-HSA-6814764 Plasma membrane resorption TAS Homo sapiens 17761 R-MMU-6810937 https://reactome.org/PathwayBrowser/#/R-MMU-6810937 Lamellar bodies bind the early cornified envelope IEA Mus musculus 17761 R-MMU-6814387 https://reactome.org/PathwayBrowser/#/R-MMU-6814387 CASP14 cleaves filaggrin IEA Mus musculus 17761 R-MMU-6814734 https://reactome.org/PathwayBrowser/#/R-MMU-6814734 CDSN binds the cornified envelope IEA Mus musculus 17761 R-MMU-6814764 https://reactome.org/PathwayBrowser/#/R-MMU-6814764 Plasma membrane resorption IEA Mus musculus 17761 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus 17761 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus 17761 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus 17761 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus 17761 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa 17775 R-BTA-2872497 https://reactome.org/PathwayBrowser/#/R-BTA-2872497 SLC17A3-2 transports cytosolic urate to extracellular region IEA Bos taurus 17775 R-BTA-429036 https://reactome.org/PathwayBrowser/#/R-BTA-429036 SLC2A9 transports Fru, Glc, urate IEA Bos taurus 17775 R-BTA-561253 https://reactome.org/PathwayBrowser/#/R-BTA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Bos taurus 17775 R-BTA-74258 https://reactome.org/PathwayBrowser/#/R-BTA-74258 XDH oxidizes xanthine to form urate IEA Bos taurus 17775 R-BTA-9727349 https://reactome.org/PathwayBrowser/#/R-BTA-9727349 XDH dehydrogenates xanthine to form urate IEA Bos taurus 17775 R-CEL-2872497 https://reactome.org/PathwayBrowser/#/R-CEL-2872497 SLC17A3-2 transports cytosolic urate to extracellular region IEA Caenorhabditis elegans 17775 R-CEL-429036 https://reactome.org/PathwayBrowser/#/R-CEL-429036 SLC2A9 transports Fru, Glc, urate IEA Caenorhabditis elegans 17775 R-CEL-561253 https://reactome.org/PathwayBrowser/#/R-CEL-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Caenorhabditis elegans 17775 R-CEL-74258 https://reactome.org/PathwayBrowser/#/R-CEL-74258 XDH oxidizes xanthine to form urate IEA Caenorhabditis elegans 17775 R-CEL-9727349 https://reactome.org/PathwayBrowser/#/R-CEL-9727349 XDH dehydrogenates xanthine to form urate IEA Caenorhabditis elegans 17775 R-CFA-2872497 https://reactome.org/PathwayBrowser/#/R-CFA-2872497 SLC17A3-2 transports cytosolic urate to extracellular region IEA Canis familiaris 17775 R-CFA-429036 https://reactome.org/PathwayBrowser/#/R-CFA-429036 SLC2A9 transports Fru, Glc, urate IEA Canis familiaris 17775 R-CFA-561253 https://reactome.org/PathwayBrowser/#/R-CFA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Canis familiaris 17775 R-CFA-74258 https://reactome.org/PathwayBrowser/#/R-CFA-74258 XDH oxidizes xanthine to form urate IEA Canis familiaris 17775 R-CFA-9727349 https://reactome.org/PathwayBrowser/#/R-CFA-9727349 XDH dehydrogenates xanthine to form urate IEA Canis familiaris 17775 R-DDI-2872497 https://reactome.org/PathwayBrowser/#/R-DDI-2872497 SLC17A3-2 transports cytosolic urate to extracellular region IEA Dictyostelium discoideum 17775 R-DDI-429036 https://reactome.org/PathwayBrowser/#/R-DDI-429036 SLC2A9 transports Fru, Glc, urate IEA Dictyostelium discoideum 17775 R-DDI-74258 https://reactome.org/PathwayBrowser/#/R-DDI-74258 XDH oxidizes xanthine to form urate IEA Dictyostelium discoideum 17775 R-DDI-9727349 https://reactome.org/PathwayBrowser/#/R-DDI-9727349 XDH dehydrogenates xanthine to form urate IEA Dictyostelium discoideum 17775 R-DME-2872497 https://reactome.org/PathwayBrowser/#/R-DME-2872497 SLC17A3-2 transports cytosolic urate to extracellular region IEA Drosophila melanogaster 17775 R-DME-429036 https://reactome.org/PathwayBrowser/#/R-DME-429036 SLC2A9 transports Fru, Glc, urate IEA Drosophila melanogaster 17775 R-DME-561253 https://reactome.org/PathwayBrowser/#/R-DME-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Drosophila melanogaster 17775 R-DME-74258 https://reactome.org/PathwayBrowser/#/R-DME-74258 XDH oxidizes xanthine to form urate IEA Drosophila melanogaster 17775 R-DME-9727349 https://reactome.org/PathwayBrowser/#/R-DME-9727349 XDH dehydrogenates xanthine to form urate IEA Drosophila melanogaster 17775 R-GGA-421158 https://reactome.org/PathwayBrowser/#/R-GGA-421158 xanthine + H2O + NAD+ => urate + NADH + H+ TAS Gallus gallus 17775 R-GGA-429036 https://reactome.org/PathwayBrowser/#/R-GGA-429036 SLC2A9 transports Fru, Glc, urate IEA Gallus gallus 17775 R-GGA-74258 https://reactome.org/PathwayBrowser/#/R-GGA-74258 XDH oxidizes xanthine to form urate IEA Gallus gallus 17775 R-GGA-9727349 https://reactome.org/PathwayBrowser/#/R-GGA-9727349 XDH dehydrogenates xanthine to form urate IEA Gallus gallus 17775 R-HSA-2872497 https://reactome.org/PathwayBrowser/#/R-HSA-2872497 SLC17A3-2 transports cytosolic urate to extracellular region TAS Homo sapiens 17775 R-HSA-429036 https://reactome.org/PathwayBrowser/#/R-HSA-429036 SLC2A9 transports Fru, Glc, urate TAS Homo sapiens 17775 R-HSA-561253 https://reactome.org/PathwayBrowser/#/R-HSA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT TAS Homo sapiens 17775 R-HSA-5625210 https://reactome.org/PathwayBrowser/#/R-HSA-5625210 Defective SLC22A12 does not exchange extracellular urate for cytosolic LACT TAS Homo sapiens 17775 R-HSA-5638209 https://reactome.org/PathwayBrowser/#/R-HSA-5638209 Defective SLC2A9 does not transport Fru, Glc, urate TAS Homo sapiens 17775 R-HSA-74258 https://reactome.org/PathwayBrowser/#/R-HSA-74258 XDH oxidizes xanthine to form urate TAS Homo sapiens 17775 R-HSA-9727349 https://reactome.org/PathwayBrowser/#/R-HSA-9727349 XDH dehydrogenates xanthine to form urate TAS Homo sapiens 17775 R-MMU-2872497 https://reactome.org/PathwayBrowser/#/R-MMU-2872497 SLC17A3-2 transports cytosolic urate to extracellular region IEA Mus musculus 17775 R-MMU-429036 https://reactome.org/PathwayBrowser/#/R-MMU-429036 SLC2A9 transports Fru, Glc, urate IEA Mus musculus 17775 R-MMU-561253 https://reactome.org/PathwayBrowser/#/R-MMU-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Mus musculus 17775 R-MMU-74258 https://reactome.org/PathwayBrowser/#/R-MMU-74258 XDH oxidizes xanthine to form urate IEA Mus musculus 17775 R-MMU-9727349 https://reactome.org/PathwayBrowser/#/R-MMU-9727349 XDH dehydrogenates xanthine to form urate IEA Mus musculus 17775 R-PFA-429036 https://reactome.org/PathwayBrowser/#/R-PFA-429036 SLC2A9 transports Fru, Glc, urate IEA Plasmodium falciparum 17775 R-RNO-2872497 https://reactome.org/PathwayBrowser/#/R-RNO-2872497 SLC17A3-2 transports cytosolic urate to extracellular region IEA Rattus norvegicus 17775 R-RNO-429036 https://reactome.org/PathwayBrowser/#/R-RNO-429036 SLC2A9 transports Fru, Glc, urate IEA Rattus norvegicus 17775 R-RNO-561253 https://reactome.org/PathwayBrowser/#/R-RNO-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Rattus norvegicus 17775 R-RNO-74258 https://reactome.org/PathwayBrowser/#/R-RNO-74258 XDH oxidizes xanthine to form urate IEA Rattus norvegicus 17775 R-RNO-9727349 https://reactome.org/PathwayBrowser/#/R-RNO-9727349 XDH dehydrogenates xanthine to form urate IEA Rattus norvegicus 17775 R-SCE-429036 https://reactome.org/PathwayBrowser/#/R-SCE-429036 SLC2A9 transports Fru, Glc, urate IEA Saccharomyces cerevisiae 17775 R-SSC-2872497 https://reactome.org/PathwayBrowser/#/R-SSC-2872497 SLC17A3-2 transports cytosolic urate to extracellular region IEA Sus scrofa 17775 R-SSC-429036 https://reactome.org/PathwayBrowser/#/R-SSC-429036 SLC2A9 transports Fru, Glc, urate IEA Sus scrofa 17775 R-SSC-561253 https://reactome.org/PathwayBrowser/#/R-SSC-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Sus scrofa 17775 R-SSC-74258 https://reactome.org/PathwayBrowser/#/R-SSC-74258 XDH oxidizes xanthine to form urate IEA Sus scrofa 17775 R-SSC-9727349 https://reactome.org/PathwayBrowser/#/R-SSC-9727349 XDH dehydrogenates xanthine to form urate IEA Sus scrofa 17775 R-XTR-429036 https://reactome.org/PathwayBrowser/#/R-XTR-429036 SLC2A9 transports Fru, Glc, urate IEA Xenopus tropicalis 17775 R-XTR-74258 https://reactome.org/PathwayBrowser/#/R-XTR-74258 XDH oxidizes xanthine to form urate IEA Xenopus tropicalis 17775 R-XTR-9727349 https://reactome.org/PathwayBrowser/#/R-XTR-9727349 XDH dehydrogenates xanthine to form urate IEA Xenopus tropicalis 17790 R-BTA-5693691 https://reactome.org/PathwayBrowser/#/R-BTA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Bos taurus 17790 R-BTA-5696365 https://reactome.org/PathwayBrowser/#/R-BTA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Bos taurus 17790 R-BTA-8856951 https://reactome.org/PathwayBrowser/#/R-BTA-8856951 PP2A demethylation by PPME1 IEA Bos taurus 17790 R-CEL-5693691 https://reactome.org/PathwayBrowser/#/R-CEL-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Caenorhabditis elegans 17790 R-CEL-8856951 https://reactome.org/PathwayBrowser/#/R-CEL-8856951 PP2A demethylation by PPME1 IEA Caenorhabditis elegans 17790 R-CFA-5693691 https://reactome.org/PathwayBrowser/#/R-CFA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Canis familiaris 17790 R-CFA-5696365 https://reactome.org/PathwayBrowser/#/R-CFA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Canis familiaris 17790 R-CFA-8856951 https://reactome.org/PathwayBrowser/#/R-CFA-8856951 PP2A demethylation by PPME1 IEA Canis familiaris 17790 R-DDI-5693691 https://reactome.org/PathwayBrowser/#/R-DDI-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Dictyostelium discoideum 17790 R-DDI-8856951 https://reactome.org/PathwayBrowser/#/R-DDI-8856951 PP2A demethylation by PPME1 IEA Dictyostelium discoideum 17790 R-DME-5693691 https://reactome.org/PathwayBrowser/#/R-DME-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Drosophila melanogaster 17790 R-DME-5696365 https://reactome.org/PathwayBrowser/#/R-DME-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Drosophila melanogaster 17790 R-DME-8856951 https://reactome.org/PathwayBrowser/#/R-DME-8856951 PP2A demethylation by PPME1 IEA Drosophila melanogaster 17790 R-DRE-5693691 https://reactome.org/PathwayBrowser/#/R-DRE-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Danio rerio 17790 R-DRE-5696365 https://reactome.org/PathwayBrowser/#/R-DRE-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Danio rerio 17790 R-DRE-8856951 https://reactome.org/PathwayBrowser/#/R-DRE-8856951 PP2A demethylation by PPME1 IEA Danio rerio 17790 R-GGA-5693691 https://reactome.org/PathwayBrowser/#/R-GGA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Gallus gallus 17790 R-GGA-5696365 https://reactome.org/PathwayBrowser/#/R-GGA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Gallus gallus 17790 R-HSA-2408530 https://reactome.org/PathwayBrowser/#/R-HSA-2408530 MeSeH is hydrolysed to H2Se by methylselenol demethylase IEA Homo sapiens 17790 R-HSA-5693691 https://reactome.org/PathwayBrowser/#/R-HSA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG TAS Homo sapiens 17790 R-HSA-5696365 https://reactome.org/PathwayBrowser/#/R-HSA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe TAS Homo sapiens 17790 R-HSA-8856951 https://reactome.org/PathwayBrowser/#/R-HSA-8856951 PP2A demethylation by PPME1 TAS Homo sapiens 17790 R-MMU-5693691 https://reactome.org/PathwayBrowser/#/R-MMU-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Mus musculus 17790 R-MMU-5696365 https://reactome.org/PathwayBrowser/#/R-MMU-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Mus musculus 17790 R-MMU-8856951 https://reactome.org/PathwayBrowser/#/R-MMU-8856951 PP2A demethylation by PPME1 IEA Mus musculus 17790 R-RNO-2408521 https://reactome.org/PathwayBrowser/#/R-RNO-2408521 MeSeH is hydrolysed to H2Se by methylselenol demethylase TAS Rattus norvegicus 17790 R-RNO-5693691 https://reactome.org/PathwayBrowser/#/R-RNO-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Rattus norvegicus 17790 R-RNO-5696365 https://reactome.org/PathwayBrowser/#/R-RNO-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Rattus norvegicus 17790 R-RNO-8856951 https://reactome.org/PathwayBrowser/#/R-RNO-8856951 PP2A demethylation by PPME1 IEA Rattus norvegicus 17790 R-SCE-8856951 https://reactome.org/PathwayBrowser/#/R-SCE-8856951 PP2A demethylation by PPME1 IEA Saccharomyces cerevisiae 17790 R-SPO-8856951 https://reactome.org/PathwayBrowser/#/R-SPO-8856951 PP2A demethylation by PPME1 IEA Schizosaccharomyces pombe 17790 R-SSC-5693691 https://reactome.org/PathwayBrowser/#/R-SSC-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Sus scrofa 17790 R-SSC-5696365 https://reactome.org/PathwayBrowser/#/R-SSC-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Sus scrofa 17790 R-SSC-8856951 https://reactome.org/PathwayBrowser/#/R-SSC-8856951 PP2A demethylation by PPME1 IEA Sus scrofa 17790 R-XTR-5693691 https://reactome.org/PathwayBrowser/#/R-XTR-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Xenopus tropicalis 17790 R-XTR-8856951 https://reactome.org/PathwayBrowser/#/R-XTR-8856951 PP2A demethylation by PPME1 IEA Xenopus tropicalis 17802 R-BTA-6788295 https://reactome.org/PathwayBrowser/#/R-BTA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Bos taurus 17802 R-CEL-6788295 https://reactome.org/PathwayBrowser/#/R-CEL-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Caenorhabditis elegans 17802 R-CFA-6788295 https://reactome.org/PathwayBrowser/#/R-CFA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Canis familiaris 17802 R-DME-6788295 https://reactome.org/PathwayBrowser/#/R-DME-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Drosophila melanogaster 17802 R-DRE-6788295 https://reactome.org/PathwayBrowser/#/R-DRE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Danio rerio 17802 R-GGA-6788295 https://reactome.org/PathwayBrowser/#/R-GGA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Gallus gallus 17802 R-HSA-6788295 https://reactome.org/PathwayBrowser/#/R-HSA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP TAS Homo sapiens 17802 R-MMU-6788295 https://reactome.org/PathwayBrowser/#/R-MMU-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Mus musculus 17802 R-RNO-6788295 https://reactome.org/PathwayBrowser/#/R-RNO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Rattus norvegicus 17802 R-SCE-6788295 https://reactome.org/PathwayBrowser/#/R-SCE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Saccharomyces cerevisiae 17802 R-SPO-6788295 https://reactome.org/PathwayBrowser/#/R-SPO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Schizosaccharomyces pombe 17802 R-SSC-6788295 https://reactome.org/PathwayBrowser/#/R-SSC-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Sus scrofa 17802 R-XTR-6788295 https://reactome.org/PathwayBrowser/#/R-XTR-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Xenopus tropicalis 17804 R-BTA-1474184 https://reactome.org/PathwayBrowser/#/R-BTA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Bos taurus 17804 R-BTA-1475414 https://reactome.org/PathwayBrowser/#/R-BTA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Bos taurus 17804 R-CEL-1474184 https://reactome.org/PathwayBrowser/#/R-CEL-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Caenorhabditis elegans 17804 R-CFA-1475414 https://reactome.org/PathwayBrowser/#/R-CFA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Canis familiaris 17804 R-DDI-1474184 https://reactome.org/PathwayBrowser/#/R-DDI-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Dictyostelium discoideum 17804 R-DDI-1475414 https://reactome.org/PathwayBrowser/#/R-DDI-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Dictyostelium discoideum 17804 R-DME-1474184 https://reactome.org/PathwayBrowser/#/R-DME-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Drosophila melanogaster 17804 R-DME-1475414 https://reactome.org/PathwayBrowser/#/R-DME-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Drosophila melanogaster 17804 R-DRE-1474184 https://reactome.org/PathwayBrowser/#/R-DRE-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Danio rerio 17804 R-DRE-1475414 https://reactome.org/PathwayBrowser/#/R-DRE-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Danio rerio 17804 R-GGA-1474184 https://reactome.org/PathwayBrowser/#/R-GGA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Gallus gallus 17804 R-GGA-1475414 https://reactome.org/PathwayBrowser/#/R-GGA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Gallus gallus 17804 R-HSA-1474184 https://reactome.org/PathwayBrowser/#/R-HSA-1474184 DHNTP is dephosphorylated by PTPS to PTHP TAS Homo sapiens 17804 R-HSA-1475414 https://reactome.org/PathwayBrowser/#/R-HSA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) TAS Homo sapiens 17804 R-HSA-9693722 https://reactome.org/PathwayBrowser/#/R-HSA-9693722 Unknown sepiapterin synthase transforms PTHP to sepiapterin TAS Homo sapiens 17804 R-MMU-1474184 https://reactome.org/PathwayBrowser/#/R-MMU-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Mus musculus 17804 R-MMU-1475414 https://reactome.org/PathwayBrowser/#/R-MMU-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Mus musculus 17804 R-PFA-1474184 https://reactome.org/PathwayBrowser/#/R-PFA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Plasmodium falciparum 17804 R-RNO-1474184 https://reactome.org/PathwayBrowser/#/R-RNO-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Rattus norvegicus 17804 R-RNO-1475414 https://reactome.org/PathwayBrowser/#/R-RNO-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Rattus norvegicus 17804 R-SSC-1474184 https://reactome.org/PathwayBrowser/#/R-SSC-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Sus scrofa 17804 R-SSC-1475414 https://reactome.org/PathwayBrowser/#/R-SSC-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Sus scrofa 17804 R-XTR-1474184 https://reactome.org/PathwayBrowser/#/R-XTR-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Xenopus tropicalis 17804 R-XTR-1475414 https://reactome.org/PathwayBrowser/#/R-XTR-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Xenopus tropicalis 17806 R-HSA-5333607 https://reactome.org/PathwayBrowser/#/R-HSA-5333607 GSSeH combines with bGalNAc derivative to form GSSebGalNac IEA Homo sapiens 17810 R-BTA-8874435 https://reactome.org/PathwayBrowser/#/R-BTA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Bos taurus 17810 R-CEL-8874435 https://reactome.org/PathwayBrowser/#/R-CEL-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Caenorhabditis elegans 17810 R-CFA-8874435 https://reactome.org/PathwayBrowser/#/R-CFA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Canis familiaris 17810 R-DDI-8874435 https://reactome.org/PathwayBrowser/#/R-DDI-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Dictyostelium discoideum 17810 R-DME-8874435 https://reactome.org/PathwayBrowser/#/R-DME-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Drosophila melanogaster 17810 R-DRE-8874435 https://reactome.org/PathwayBrowser/#/R-DRE-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Danio rerio 17810 R-HSA-8874435 https://reactome.org/PathwayBrowser/#/R-HSA-8874435 THEM86B hydrolyses PMCHO, PMETAM TAS Homo sapiens 17810 R-MMU-8874435 https://reactome.org/PathwayBrowser/#/R-MMU-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Mus musculus 17810 R-RNO-8874435 https://reactome.org/PathwayBrowser/#/R-RNO-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Rattus norvegicus 17810 R-SSC-8874435 https://reactome.org/PathwayBrowser/#/R-SSC-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Sus scrofa 17810 R-XTR-8874435 https://reactome.org/PathwayBrowser/#/R-XTR-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Xenopus tropicalis 17813 R-BTA-194641 https://reactome.org/PathwayBrowser/#/R-BTA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 17813 R-BTA-194674 https://reactome.org/PathwayBrowser/#/R-BTA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Bos taurus 17813 R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 17813 R-BTA-194698 https://reactome.org/PathwayBrowser/#/R-BTA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Bos taurus 17813 R-CFA-194641 https://reactome.org/PathwayBrowser/#/R-CFA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 17813 R-CFA-194674 https://reactome.org/PathwayBrowser/#/R-CFA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Canis familiaris 17813 R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 17813 R-CFA-194698 https://reactome.org/PathwayBrowser/#/R-CFA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Canis familiaris 17813 R-DDI-194641 https://reactome.org/PathwayBrowser/#/R-DDI-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 17813 R-DDI-194674 https://reactome.org/PathwayBrowser/#/R-DDI-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Dictyostelium discoideum 17813 R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 17813 R-DDI-194698 https://reactome.org/PathwayBrowser/#/R-DDI-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Dictyostelium discoideum 17813 R-DME-194698 https://reactome.org/PathwayBrowser/#/R-DME-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Drosophila melanogaster 17813 R-DRE-194641 https://reactome.org/PathwayBrowser/#/R-DRE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 17813 R-DRE-194674 https://reactome.org/PathwayBrowser/#/R-DRE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Danio rerio 17813 R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 17813 R-DRE-194698 https://reactome.org/PathwayBrowser/#/R-DRE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Danio rerio 17813 R-GGA-194641 https://reactome.org/PathwayBrowser/#/R-GGA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 17813 R-GGA-194674 https://reactome.org/PathwayBrowser/#/R-GGA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Gallus gallus 17813 R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 17813 R-HSA-194641 https://reactome.org/PathwayBrowser/#/R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 17813 R-HSA-194674 https://reactome.org/PathwayBrowser/#/R-HSA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] TAS Homo sapiens 17813 R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 17813 R-HSA-194698 https://reactome.org/PathwayBrowser/#/R-HSA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] TAS Homo sapiens 17813 R-MMU-194641 https://reactome.org/PathwayBrowser/#/R-MMU-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 17813 R-MMU-194674 https://reactome.org/PathwayBrowser/#/R-MMU-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Mus musculus 17813 R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 17813 R-MMU-194698 https://reactome.org/PathwayBrowser/#/R-MMU-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Mus musculus 17813 R-RNO-194641 https://reactome.org/PathwayBrowser/#/R-RNO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 17813 R-RNO-194674 https://reactome.org/PathwayBrowser/#/R-RNO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Rattus norvegicus 17813 R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 17813 R-RNO-194698 https://reactome.org/PathwayBrowser/#/R-RNO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Rattus norvegicus 17813 R-SCE-194641 https://reactome.org/PathwayBrowser/#/R-SCE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 17813 R-SCE-194674 https://reactome.org/PathwayBrowser/#/R-SCE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Saccharomyces cerevisiae 17813 R-SCE-194678 https://reactome.org/PathwayBrowser/#/R-SCE-194678 CYP51A1 demethylates LNSOL IEA Saccharomyces cerevisiae 17813 R-SCE-194698 https://reactome.org/PathwayBrowser/#/R-SCE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Saccharomyces cerevisiae 17813 R-SPO-194641 https://reactome.org/PathwayBrowser/#/R-SPO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 17813 R-SPO-194674 https://reactome.org/PathwayBrowser/#/R-SPO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Schizosaccharomyces pombe 17813 R-SPO-194678 https://reactome.org/PathwayBrowser/#/R-SPO-194678 CYP51A1 demethylates LNSOL IEA Schizosaccharomyces pombe 17813 R-SPO-194698 https://reactome.org/PathwayBrowser/#/R-SPO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Schizosaccharomyces pombe 17813 R-SSC-194641 https://reactome.org/PathwayBrowser/#/R-SSC-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 17813 R-SSC-194674 https://reactome.org/PathwayBrowser/#/R-SSC-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Sus scrofa 17813 R-SSC-194678 https://reactome.org/PathwayBrowser/#/R-SSC-194678 CYP51A1 demethylates LNSOL IEA Sus scrofa 17813 R-SSC-194698 https://reactome.org/PathwayBrowser/#/R-SSC-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Sus scrofa 17813 R-XTR-194641 https://reactome.org/PathwayBrowser/#/R-XTR-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 17813 R-XTR-194674 https://reactome.org/PathwayBrowser/#/R-XTR-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Xenopus tropicalis 17814 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 17814 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 17814 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 17814 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 17814 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 17814 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 17814 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 17814 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 17814 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 17814 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 17814 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 17814 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 17814 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 17814 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 17814 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 17814 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 17814 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 17814 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 17814 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 17814 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 17814 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 17814 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 17814 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 17814 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 17814 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 17814 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 17814 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 17814 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 17814 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 17814 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 17814 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 17814 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 17814 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 17814 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 17814 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 17814 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 17814 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 17814 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 17814 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 17814 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 17814 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 17814 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 17815 R-BTA-1112666 https://reactome.org/PathwayBrowser/#/R-BTA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Bos taurus 17815 R-BTA-114553 https://reactome.org/PathwayBrowser/#/R-BTA-114553 Activation of conventional Protein Kinase C IEA Bos taurus 17815 R-BTA-114683 https://reactome.org/PathwayBrowser/#/R-BTA-114683 Phosphorylation of Platelet Sec-1 IEA Bos taurus 17815 R-BTA-114684 https://reactome.org/PathwayBrowser/#/R-BTA-114684 Phosphorylation of Syntaxin-4 IEA Bos taurus 17815 R-BTA-114688 https://reactome.org/PathwayBrowser/#/R-BTA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Bos taurus 17815 R-BTA-114689 https://reactome.org/PathwayBrowser/#/R-BTA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Bos taurus 17815 R-BTA-1168373 https://reactome.org/PathwayBrowser/#/R-BTA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Bos taurus 17815 R-BTA-1168635 https://reactome.org/PathwayBrowser/#/R-BTA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Bos taurus 17815 R-BTA-1168636 https://reactome.org/PathwayBrowser/#/R-BTA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Bos taurus 17815 R-BTA-1482647 https://reactome.org/PathwayBrowser/#/R-BTA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Bos taurus 17815 R-BTA-1482654 https://reactome.org/PathwayBrowser/#/R-BTA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Bos taurus 17815 R-BTA-1482777 https://reactome.org/PathwayBrowser/#/R-BTA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Bos taurus 17815 R-BTA-1482811 https://reactome.org/PathwayBrowser/#/R-BTA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Bos taurus 17815 R-BTA-1482889 https://reactome.org/PathwayBrowser/#/R-BTA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Bos taurus 17815 R-BTA-1482961 https://reactome.org/PathwayBrowser/#/R-BTA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Bos taurus 17815 R-BTA-1482962 https://reactome.org/PathwayBrowser/#/R-BTA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Bos taurus 17815 R-BTA-1482973 https://reactome.org/PathwayBrowser/#/R-BTA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Bos taurus 17815 R-BTA-1483203 https://reactome.org/PathwayBrowser/#/R-BTA-1483203 PA is dephosphorylated to DAG by LPIN IEA Bos taurus 17815 R-BTA-162798 https://reactome.org/PathwayBrowser/#/R-BTA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Bos taurus 17815 R-BTA-1855177 https://reactome.org/PathwayBrowser/#/R-BTA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Bos taurus 17815 R-BTA-1855214 https://reactome.org/PathwayBrowser/#/R-BTA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Bos taurus 17815 R-BTA-1855221 https://reactome.org/PathwayBrowser/#/R-BTA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Bos taurus 17815 R-BTA-354173 https://reactome.org/PathwayBrowser/#/R-BTA-354173 Activation of Rap1 by cytosolic GEFs IEA Bos taurus 17815 R-BTA-398193 https://reactome.org/PathwayBrowser/#/R-BTA-398193 PLC beta-mediated PIP2 hydrolysis IEA Bos taurus 17815 R-BTA-399998 https://reactome.org/PathwayBrowser/#/R-BTA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Bos taurus 17815 R-BTA-416639 https://reactome.org/PathwayBrowser/#/R-BTA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Bos taurus 17815 R-BTA-421007 https://reactome.org/PathwayBrowser/#/R-BTA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Bos taurus 17815 R-BTA-425861 https://reactome.org/PathwayBrowser/#/R-BTA-425861 Activation of Protein Kinase C novel isoforms IEA Bos taurus 17815 R-BTA-426032 https://reactome.org/PathwayBrowser/#/R-BTA-426032 DAG is metabolized by DAGL to 2-AG IEA Bos taurus 17815 R-BTA-426209 https://reactome.org/PathwayBrowser/#/R-BTA-426209 DAG activation of TRPC channels IEA Bos taurus 17815 R-BTA-426223 https://reactome.org/PathwayBrowser/#/R-BTA-426223 Cation influx mediated by TRPC3/6/7 IEA Bos taurus 17815 R-BTA-426240 https://reactome.org/PathwayBrowser/#/R-BTA-426240 DAG kinase produces phosphatidic acid from DAG IEA Bos taurus 17815 R-BTA-429786 https://reactome.org/PathwayBrowser/#/R-BTA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Bos taurus 17815 R-BTA-429798 https://reactome.org/PathwayBrowser/#/R-BTA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Bos taurus 17815 R-BTA-5138432 https://reactome.org/PathwayBrowser/#/R-BTA-5138432 DVL2 is phosphorylated by PKC IEA Bos taurus 17815 R-BTA-5221130 https://reactome.org/PathwayBrowser/#/R-BTA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Bos taurus 17815 R-BTA-5223304 https://reactome.org/PathwayBrowser/#/R-BTA-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Bos taurus 17815 R-BTA-5229194 https://reactome.org/PathwayBrowser/#/R-BTA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Bos taurus 17815 R-BTA-5672965 https://reactome.org/PathwayBrowser/#/R-BTA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Bos taurus 17815 R-BTA-5696074 https://reactome.org/PathwayBrowser/#/R-BTA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Bos taurus 17815 R-BTA-5696448 https://reactome.org/PathwayBrowser/#/R-BTA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Bos taurus 17815 R-BTA-6797630 https://reactome.org/PathwayBrowser/#/R-BTA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Bos taurus 17815 R-BTA-6800334 https://reactome.org/PathwayBrowser/#/R-BTA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Bos taurus 17815 R-BTA-75899 https://reactome.org/PathwayBrowser/#/R-BTA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Bos taurus 17815 R-BTA-75900 https://reactome.org/PathwayBrowser/#/R-BTA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Bos taurus 17815 R-BTA-8848338 https://reactome.org/PathwayBrowser/#/R-BTA-8848338 PNPLA4 hydrolyzes TAG IEA Bos taurus 17815 R-BTA-8848580 https://reactome.org/PathwayBrowser/#/R-BTA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Bos taurus 17815 R-BTA-8959462 https://reactome.org/PathwayBrowser/#/R-BTA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Bos taurus 17815 R-CEL-114553 https://reactome.org/PathwayBrowser/#/R-CEL-114553 Activation of conventional Protein Kinase C IEA Caenorhabditis elegans 17815 R-CEL-114683 https://reactome.org/PathwayBrowser/#/R-CEL-114683 Phosphorylation of Platelet Sec-1 IEA Caenorhabditis elegans 17815 R-CEL-114684 https://reactome.org/PathwayBrowser/#/R-CEL-114684 Phosphorylation of Syntaxin-4 IEA Caenorhabditis elegans 17815 R-CEL-114688 https://reactome.org/PathwayBrowser/#/R-CEL-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Caenorhabditis elegans 17815 R-CEL-1168373 https://reactome.org/PathwayBrowser/#/R-CEL-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Caenorhabditis elegans 17815 R-CEL-1168636 https://reactome.org/PathwayBrowser/#/R-CEL-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Caenorhabditis elegans 17815 R-CEL-1482647 https://reactome.org/PathwayBrowser/#/R-CEL-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Caenorhabditis elegans 17815 R-CEL-1482654 https://reactome.org/PathwayBrowser/#/R-CEL-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Caenorhabditis elegans 17815 R-CEL-1482777 https://reactome.org/PathwayBrowser/#/R-CEL-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Caenorhabditis elegans 17815 R-CEL-1482811 https://reactome.org/PathwayBrowser/#/R-CEL-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Caenorhabditis elegans 17815 R-CEL-1482889 https://reactome.org/PathwayBrowser/#/R-CEL-1482889 DAG is acylated to TAG by DGAT1/2 IEA Caenorhabditis elegans 17815 R-CEL-1482961 https://reactome.org/PathwayBrowser/#/R-CEL-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Caenorhabditis elegans 17815 R-CEL-1482962 https://reactome.org/PathwayBrowser/#/R-CEL-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Caenorhabditis elegans 17815 R-CEL-1482973 https://reactome.org/PathwayBrowser/#/R-CEL-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Caenorhabditis elegans 17815 R-CEL-1483203 https://reactome.org/PathwayBrowser/#/R-CEL-1483203 PA is dephosphorylated to DAG by LPIN IEA Caenorhabditis elegans 17815 R-CEL-162798 https://reactome.org/PathwayBrowser/#/R-CEL-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Caenorhabditis elegans 17815 R-CEL-1855177 https://reactome.org/PathwayBrowser/#/R-CEL-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Caenorhabditis elegans 17815 R-CEL-1855214 https://reactome.org/PathwayBrowser/#/R-CEL-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Caenorhabditis elegans 17815 R-CEL-1855221 https://reactome.org/PathwayBrowser/#/R-CEL-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Caenorhabditis elegans 17815 R-CEL-2179413 https://reactome.org/PathwayBrowser/#/R-CEL-2179413 Activated PKC-alpha activate MMP3 IEA Caenorhabditis elegans 17815 R-CEL-2750187 https://reactome.org/PathwayBrowser/#/R-CEL-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Caenorhabditis elegans 17815 R-CEL-354173 https://reactome.org/PathwayBrowser/#/R-CEL-354173 Activation of Rap1 by cytosolic GEFs IEA Caenorhabditis elegans 17815 R-CEL-400015 https://reactome.org/PathwayBrowser/#/R-CEL-400015 Diacylgycerol activates Protein kinase C, alpha type IEA Caenorhabditis elegans 17815 R-CEL-425861 https://reactome.org/PathwayBrowser/#/R-CEL-425861 Activation of Protein Kinase C novel isoforms IEA Caenorhabditis elegans 17815 R-CEL-426032 https://reactome.org/PathwayBrowser/#/R-CEL-426032 DAG is metabolized by DAGL to 2-AG IEA Caenorhabditis elegans 17815 R-CEL-426209 https://reactome.org/PathwayBrowser/#/R-CEL-426209 DAG activation of TRPC channels IEA Caenorhabditis elegans 17815 R-CEL-426223 https://reactome.org/PathwayBrowser/#/R-CEL-426223 Cation influx mediated by TRPC3/6/7 IEA Caenorhabditis elegans 17815 R-CEL-426240 https://reactome.org/PathwayBrowser/#/R-CEL-426240 DAG kinase produces phosphatidic acid from DAG IEA Caenorhabditis elegans 17815 R-CEL-429786 https://reactome.org/PathwayBrowser/#/R-CEL-429786 SGMS2 transfers phosphocholine onto ceramide IEA Caenorhabditis elegans 17815 R-CEL-429798 https://reactome.org/PathwayBrowser/#/R-CEL-429798 SGMS1 transfers phosphocholine onto ceramide IEA Caenorhabditis elegans 17815 R-CEL-5138432 https://reactome.org/PathwayBrowser/#/R-CEL-5138432 DVL2 is phosphorylated by PKC IEA Caenorhabditis elegans 17815 R-CEL-5221130 https://reactome.org/PathwayBrowser/#/R-CEL-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Caenorhabditis elegans 17815 R-CEL-5223304 https://reactome.org/PathwayBrowser/#/R-CEL-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Caenorhabditis elegans 17815 R-CEL-549192 https://reactome.org/PathwayBrowser/#/R-CEL-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Caenorhabditis elegans 17815 R-CEL-5672965 https://reactome.org/PathwayBrowser/#/R-CEL-5672965 RAS GEFs promote RAS nucleotide exchange IEA Caenorhabditis elegans 17815 R-CEL-5696074 https://reactome.org/PathwayBrowser/#/R-CEL-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Caenorhabditis elegans 17815 R-CEL-5696448 https://reactome.org/PathwayBrowser/#/R-CEL-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Caenorhabditis elegans 17815 R-CEL-6797630 https://reactome.org/PathwayBrowser/#/R-CEL-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Caenorhabditis elegans 17815 R-CEL-6800334 https://reactome.org/PathwayBrowser/#/R-CEL-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Caenorhabditis elegans 17815 R-CEL-75899 https://reactome.org/PathwayBrowser/#/R-CEL-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Caenorhabditis elegans 17815 R-CEL-75900 https://reactome.org/PathwayBrowser/#/R-CEL-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Caenorhabditis elegans 17815 R-CEL-8848339 https://reactome.org/PathwayBrowser/#/R-CEL-8848339 PNPLA5 hydrolyzes TAG IEA Caenorhabditis elegans 17815 R-CEL-8848580 https://reactome.org/PathwayBrowser/#/R-CEL-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Caenorhabditis elegans 17815 R-CEL-8959462 https://reactome.org/PathwayBrowser/#/R-CEL-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Caenorhabditis elegans 17815 R-CFA-1112666 https://reactome.org/PathwayBrowser/#/R-CFA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Canis familiaris 17815 R-CFA-114553 https://reactome.org/PathwayBrowser/#/R-CFA-114553 Activation of conventional Protein Kinase C IEA Canis familiaris 17815 R-CFA-114683 https://reactome.org/PathwayBrowser/#/R-CFA-114683 Phosphorylation of Platelet Sec-1 IEA Canis familiaris 17815 R-CFA-114684 https://reactome.org/PathwayBrowser/#/R-CFA-114684 Phosphorylation of Syntaxin-4 IEA Canis familiaris 17815 R-CFA-114688 https://reactome.org/PathwayBrowser/#/R-CFA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Canis familiaris 17815 R-CFA-114689 https://reactome.org/PathwayBrowser/#/R-CFA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Canis familiaris 17815 R-CFA-1168373 https://reactome.org/PathwayBrowser/#/R-CFA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Canis familiaris 17815 R-CFA-1168635 https://reactome.org/PathwayBrowser/#/R-CFA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Canis familiaris 17815 R-CFA-1168636 https://reactome.org/PathwayBrowser/#/R-CFA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Canis familiaris 17815 R-CFA-1482647 https://reactome.org/PathwayBrowser/#/R-CFA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Canis familiaris 17815 R-CFA-1482654 https://reactome.org/PathwayBrowser/#/R-CFA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Canis familiaris 17815 R-CFA-1482777 https://reactome.org/PathwayBrowser/#/R-CFA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Canis familiaris 17815 R-CFA-1482811 https://reactome.org/PathwayBrowser/#/R-CFA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Canis familiaris 17815 R-CFA-1482889 https://reactome.org/PathwayBrowser/#/R-CFA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Canis familiaris 17815 R-CFA-1482961 https://reactome.org/PathwayBrowser/#/R-CFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Canis familiaris 17815 R-CFA-1482962 https://reactome.org/PathwayBrowser/#/R-CFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Canis familiaris 17815 R-CFA-1482973 https://reactome.org/PathwayBrowser/#/R-CFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Canis familiaris 17815 R-CFA-1483203 https://reactome.org/PathwayBrowser/#/R-CFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Canis familiaris 17815 R-CFA-162798 https://reactome.org/PathwayBrowser/#/R-CFA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Canis familiaris 17815 R-CFA-1855177 https://reactome.org/PathwayBrowser/#/R-CFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Canis familiaris 17815 R-CFA-1855214 https://reactome.org/PathwayBrowser/#/R-CFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Canis familiaris 17815 R-CFA-1855221 https://reactome.org/PathwayBrowser/#/R-CFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Canis familiaris 17815 R-CFA-2179413 https://reactome.org/PathwayBrowser/#/R-CFA-2179413 Activated PKC-alpha activate MMP3 IEA Canis familiaris 17815 R-CFA-2750187 https://reactome.org/PathwayBrowser/#/R-CFA-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Canis familiaris 17815 R-CFA-354173 https://reactome.org/PathwayBrowser/#/R-CFA-354173 Activation of Rap1 by cytosolic GEFs IEA Canis familiaris 17815 R-CFA-398193 https://reactome.org/PathwayBrowser/#/R-CFA-398193 PLC beta-mediated PIP2 hydrolysis IEA Canis familiaris 17815 R-CFA-399978 https://reactome.org/PathwayBrowser/#/R-CFA-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Canis familiaris 17815 R-CFA-399998 https://reactome.org/PathwayBrowser/#/R-CFA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Canis familiaris 17815 R-CFA-400015 https://reactome.org/PathwayBrowser/#/R-CFA-400015 Diacylgycerol activates Protein kinase C, alpha type IEA Canis familiaris 17815 R-CFA-416639 https://reactome.org/PathwayBrowser/#/R-CFA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Canis familiaris 17815 R-CFA-421007 https://reactome.org/PathwayBrowser/#/R-CFA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Canis familiaris 17815 R-CFA-425861 https://reactome.org/PathwayBrowser/#/R-CFA-425861 Activation of Protein Kinase C novel isoforms IEA Canis familiaris 17815 R-CFA-426032 https://reactome.org/PathwayBrowser/#/R-CFA-426032 DAG is metabolized by DAGL to 2-AG IEA Canis familiaris 17815 R-CFA-426209 https://reactome.org/PathwayBrowser/#/R-CFA-426209 DAG activation of TRPC channels IEA Canis familiaris 17815 R-CFA-426223 https://reactome.org/PathwayBrowser/#/R-CFA-426223 Cation influx mediated by TRPC3/6/7 IEA Canis familiaris 17815 R-CFA-426240 https://reactome.org/PathwayBrowser/#/R-CFA-426240 DAG kinase produces phosphatidic acid from DAG IEA Canis familiaris 17815 R-CFA-429786 https://reactome.org/PathwayBrowser/#/R-CFA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Canis familiaris 17815 R-CFA-429798 https://reactome.org/PathwayBrowser/#/R-CFA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Canis familiaris 17815 R-CFA-5138432 https://reactome.org/PathwayBrowser/#/R-CFA-5138432 DVL2 is phosphorylated by PKC IEA Canis familiaris 17815 R-CFA-5221130 https://reactome.org/PathwayBrowser/#/R-CFA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Canis familiaris 17815 R-CFA-5223304 https://reactome.org/PathwayBrowser/#/R-CFA-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Canis familiaris 17815 R-CFA-5229194 https://reactome.org/PathwayBrowser/#/R-CFA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Canis familiaris 17815 R-CFA-549192 https://reactome.org/PathwayBrowser/#/R-CFA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Canis familiaris 17815 R-CFA-5672965 https://reactome.org/PathwayBrowser/#/R-CFA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Canis familiaris 17815 R-CFA-5696074 https://reactome.org/PathwayBrowser/#/R-CFA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Canis familiaris 17815 R-CFA-5696448 https://reactome.org/PathwayBrowser/#/R-CFA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Canis familiaris 17815 R-CFA-6797630 https://reactome.org/PathwayBrowser/#/R-CFA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Canis familiaris 17815 R-CFA-6800334 https://reactome.org/PathwayBrowser/#/R-CFA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Canis familiaris 17815 R-CFA-75899 https://reactome.org/PathwayBrowser/#/R-CFA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Canis familiaris 17815 R-CFA-75900 https://reactome.org/PathwayBrowser/#/R-CFA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Canis familiaris 17815 R-CFA-8848338 https://reactome.org/PathwayBrowser/#/R-CFA-8848338 PNPLA4 hydrolyzes TAG IEA Canis familiaris 17815 R-CFA-8848339 https://reactome.org/PathwayBrowser/#/R-CFA-8848339 PNPLA5 hydrolyzes TAG IEA Canis familiaris 17815 R-CFA-8934446 https://reactome.org/PathwayBrowser/#/R-CFA-8934446 Activated PKC phosphorylates SHC1 IEA Canis familiaris 17815 R-CFA-8959462 https://reactome.org/PathwayBrowser/#/R-CFA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Canis familiaris 17815 R-DDI-114553 https://reactome.org/PathwayBrowser/#/R-DDI-114553 Activation of conventional Protein Kinase C IEA Dictyostelium discoideum 17815 R-DDI-114683 https://reactome.org/PathwayBrowser/#/R-DDI-114683 Phosphorylation of Platelet Sec-1 IEA Dictyostelium discoideum 17815 R-DDI-114684 https://reactome.org/PathwayBrowser/#/R-DDI-114684 Phosphorylation of Syntaxin-4 IEA Dictyostelium discoideum 17815 R-DDI-114688 https://reactome.org/PathwayBrowser/#/R-DDI-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Dictyostelium discoideum 17815 R-DDI-114689 https://reactome.org/PathwayBrowser/#/R-DDI-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Dictyostelium discoideum 17815 R-DDI-1168373 https://reactome.org/PathwayBrowser/#/R-DDI-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Dictyostelium discoideum 17815 R-DDI-1482889 https://reactome.org/PathwayBrowser/#/R-DDI-1482889 DAG is acylated to TAG by DGAT1/2 IEA Dictyostelium discoideum 17815 R-DDI-1482961 https://reactome.org/PathwayBrowser/#/R-DDI-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Dictyostelium discoideum 17815 R-DDI-1482962 https://reactome.org/PathwayBrowser/#/R-DDI-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Dictyostelium discoideum 17815 R-DDI-1482973 https://reactome.org/PathwayBrowser/#/R-DDI-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Dictyostelium discoideum 17815 R-DDI-1483203 https://reactome.org/PathwayBrowser/#/R-DDI-1483203 PA is dephosphorylated to DAG by LPIN IEA Dictyostelium discoideum 17815 R-DDI-162798 https://reactome.org/PathwayBrowser/#/R-DDI-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Dictyostelium discoideum 17815 R-DDI-1855177 https://reactome.org/PathwayBrowser/#/R-DDI-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Dictyostelium discoideum 17815 R-DDI-1855214 https://reactome.org/PathwayBrowser/#/R-DDI-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Dictyostelium discoideum 17815 R-DDI-1855221 https://reactome.org/PathwayBrowser/#/R-DDI-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Dictyostelium discoideum 17815 R-DDI-354173 https://reactome.org/PathwayBrowser/#/R-DDI-354173 Activation of Rap1 by cytosolic GEFs IEA Dictyostelium discoideum 17815 R-DDI-399998 https://reactome.org/PathwayBrowser/#/R-DDI-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Dictyostelium discoideum 17815 R-DDI-400015 https://reactome.org/PathwayBrowser/#/R-DDI-400015 Diacylgycerol activates Protein kinase C, alpha type IEA Dictyostelium discoideum 17815 R-DDI-425861 https://reactome.org/PathwayBrowser/#/R-DDI-425861 Activation of Protein Kinase C novel isoforms IEA Dictyostelium discoideum 17815 R-DDI-426032 https://reactome.org/PathwayBrowser/#/R-DDI-426032 DAG is metabolized by DAGL to 2-AG IEA Dictyostelium discoideum 17815 R-DDI-426240 https://reactome.org/PathwayBrowser/#/R-DDI-426240 DAG kinase produces phosphatidic acid from DAG IEA Dictyostelium discoideum 17815 R-DDI-5221130 https://reactome.org/PathwayBrowser/#/R-DDI-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Dictyostelium discoideum 17815 R-DDI-5223304 https://reactome.org/PathwayBrowser/#/R-DDI-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Dictyostelium discoideum 17815 R-DDI-549192 https://reactome.org/PathwayBrowser/#/R-DDI-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Dictyostelium discoideum 17815 R-DDI-5696074 https://reactome.org/PathwayBrowser/#/R-DDI-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Dictyostelium discoideum 17815 R-DDI-5696448 https://reactome.org/PathwayBrowser/#/R-DDI-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Dictyostelium discoideum 17815 R-DDI-6797630 https://reactome.org/PathwayBrowser/#/R-DDI-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Dictyostelium discoideum 17815 R-DDI-6800334 https://reactome.org/PathwayBrowser/#/R-DDI-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Dictyostelium discoideum 17815 R-DDI-75899 https://reactome.org/PathwayBrowser/#/R-DDI-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Dictyostelium discoideum 17815 R-DDI-75900 https://reactome.org/PathwayBrowser/#/R-DDI-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Dictyostelium discoideum 17815 R-DDI-8848580 https://reactome.org/PathwayBrowser/#/R-DDI-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Dictyostelium discoideum 17815 R-DME-114553 https://reactome.org/PathwayBrowser/#/R-DME-114553 Activation of conventional Protein Kinase C IEA Drosophila melanogaster 17815 R-DME-114683 https://reactome.org/PathwayBrowser/#/R-DME-114683 Phosphorylation of Platelet Sec-1 IEA Drosophila melanogaster 17815 R-DME-114684 https://reactome.org/PathwayBrowser/#/R-DME-114684 Phosphorylation of Syntaxin-4 IEA Drosophila melanogaster 17815 R-DME-114688 https://reactome.org/PathwayBrowser/#/R-DME-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Drosophila melanogaster 17815 R-DME-114689 https://reactome.org/PathwayBrowser/#/R-DME-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Drosophila melanogaster 17815 R-DME-1168373 https://reactome.org/PathwayBrowser/#/R-DME-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Drosophila melanogaster 17815 R-DME-1482647 https://reactome.org/PathwayBrowser/#/R-DME-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Drosophila melanogaster 17815 R-DME-1482654 https://reactome.org/PathwayBrowser/#/R-DME-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Drosophila melanogaster 17815 R-DME-1482777 https://reactome.org/PathwayBrowser/#/R-DME-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Drosophila melanogaster 17815 R-DME-1482811 https://reactome.org/PathwayBrowser/#/R-DME-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Drosophila melanogaster 17815 R-DME-1482889 https://reactome.org/PathwayBrowser/#/R-DME-1482889 DAG is acylated to TAG by DGAT1/2 IEA Drosophila melanogaster 17815 R-DME-1482961 https://reactome.org/PathwayBrowser/#/R-DME-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Drosophila melanogaster 17815 R-DME-1482962 https://reactome.org/PathwayBrowser/#/R-DME-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Drosophila melanogaster 17815 R-DME-1482973 https://reactome.org/PathwayBrowser/#/R-DME-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Drosophila melanogaster 17815 R-DME-1483203 https://reactome.org/PathwayBrowser/#/R-DME-1483203 PA is dephosphorylated to DAG by LPIN IEA Drosophila melanogaster 17815 R-DME-162798 https://reactome.org/PathwayBrowser/#/R-DME-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Drosophila melanogaster 17815 R-DME-1855177 https://reactome.org/PathwayBrowser/#/R-DME-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Drosophila melanogaster 17815 R-DME-1855214 https://reactome.org/PathwayBrowser/#/R-DME-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Drosophila melanogaster 17815 R-DME-1855221 https://reactome.org/PathwayBrowser/#/R-DME-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Drosophila melanogaster 17815 R-DME-2179413 https://reactome.org/PathwayBrowser/#/R-DME-2179413 Activated PKC-alpha activate MMP3 IEA Drosophila melanogaster 17815 R-DME-2750187 https://reactome.org/PathwayBrowser/#/R-DME-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Drosophila melanogaster 17815 R-DME-398193 https://reactome.org/PathwayBrowser/#/R-DME-398193 PLC beta-mediated PIP2 hydrolysis IEA Drosophila melanogaster 17815 R-DME-399998 https://reactome.org/PathwayBrowser/#/R-DME-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Drosophila melanogaster 17815 R-DME-400015 https://reactome.org/PathwayBrowser/#/R-DME-400015 Diacylgycerol activates Protein kinase C, alpha type IEA Drosophila melanogaster 17815 R-DME-416639 https://reactome.org/PathwayBrowser/#/R-DME-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Drosophila melanogaster 17815 R-DME-421007 https://reactome.org/PathwayBrowser/#/R-DME-421007 Endocytosis of Ca impermeable AMPA receptors IEA Drosophila melanogaster 17815 R-DME-425861 https://reactome.org/PathwayBrowser/#/R-DME-425861 Activation of Protein Kinase C novel isoforms IEA Drosophila melanogaster 17815 R-DME-426032 https://reactome.org/PathwayBrowser/#/R-DME-426032 DAG is metabolized by DAGL to 2-AG IEA Drosophila melanogaster 17815 R-DME-426240 https://reactome.org/PathwayBrowser/#/R-DME-426240 DAG kinase produces phosphatidic acid from DAG IEA Drosophila melanogaster 17815 R-DME-5221130 https://reactome.org/PathwayBrowser/#/R-DME-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Drosophila melanogaster 17815 R-DME-5223304 https://reactome.org/PathwayBrowser/#/R-DME-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Drosophila melanogaster 17815 R-DME-549192 https://reactome.org/PathwayBrowser/#/R-DME-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Drosophila melanogaster 17815 R-DME-5696074 https://reactome.org/PathwayBrowser/#/R-DME-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Drosophila melanogaster 17815 R-DME-5696448 https://reactome.org/PathwayBrowser/#/R-DME-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Drosophila melanogaster 17815 R-DME-6800334 https://reactome.org/PathwayBrowser/#/R-DME-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Drosophila melanogaster 17815 R-DME-75899 https://reactome.org/PathwayBrowser/#/R-DME-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Drosophila melanogaster 17815 R-DME-75900 https://reactome.org/PathwayBrowser/#/R-DME-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Drosophila melanogaster 17815 R-DME-8848339 https://reactome.org/PathwayBrowser/#/R-DME-8848339 PNPLA5 hydrolyzes TAG IEA Drosophila melanogaster 17815 R-DME-8848580 https://reactome.org/PathwayBrowser/#/R-DME-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Drosophila melanogaster 17815 R-DME-8934446 https://reactome.org/PathwayBrowser/#/R-DME-8934446 Activated PKC phosphorylates SHC1 IEA Drosophila melanogaster 17815 R-DME-8959462 https://reactome.org/PathwayBrowser/#/R-DME-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Drosophila melanogaster 17815 R-DRE-114553 https://reactome.org/PathwayBrowser/#/R-DRE-114553 Activation of conventional Protein Kinase C IEA Danio rerio 17815 R-DRE-114684 https://reactome.org/PathwayBrowser/#/R-DRE-114684 Phosphorylation of Syntaxin-4 IEA Danio rerio 17815 R-DRE-1168373 https://reactome.org/PathwayBrowser/#/R-DRE-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Danio rerio 17815 R-DRE-1168636 https://reactome.org/PathwayBrowser/#/R-DRE-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Danio rerio 17815 R-DRE-1482647 https://reactome.org/PathwayBrowser/#/R-DRE-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Danio rerio 17815 R-DRE-1482654 https://reactome.org/PathwayBrowser/#/R-DRE-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Danio rerio 17815 R-DRE-1482777 https://reactome.org/PathwayBrowser/#/R-DRE-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Danio rerio 17815 R-DRE-1482811 https://reactome.org/PathwayBrowser/#/R-DRE-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Danio rerio 17815 R-DRE-1482889 https://reactome.org/PathwayBrowser/#/R-DRE-1482889 DAG is acylated to TAG by DGAT1/2 IEA Danio rerio 17815 R-DRE-1482961 https://reactome.org/PathwayBrowser/#/R-DRE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Danio rerio 17815 R-DRE-1482962 https://reactome.org/PathwayBrowser/#/R-DRE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Danio rerio 17815 R-DRE-1482973 https://reactome.org/PathwayBrowser/#/R-DRE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Danio rerio 17815 R-DRE-1483203 https://reactome.org/PathwayBrowser/#/R-DRE-1483203 PA is dephosphorylated to DAG by LPIN IEA Danio rerio 17815 R-DRE-162798 https://reactome.org/PathwayBrowser/#/R-DRE-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Danio rerio 17815 R-DRE-1855221 https://reactome.org/PathwayBrowser/#/R-DRE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Danio rerio 17815 R-DRE-425861 https://reactome.org/PathwayBrowser/#/R-DRE-425861 Activation of Protein Kinase C novel isoforms IEA Danio rerio 17815 R-DRE-426032 https://reactome.org/PathwayBrowser/#/R-DRE-426032 DAG is metabolized by DAGL to 2-AG IEA Danio rerio 17815 R-DRE-426209 https://reactome.org/PathwayBrowser/#/R-DRE-426209 DAG activation of TRPC channels IEA Danio rerio 17815 R-DRE-426223 https://reactome.org/PathwayBrowser/#/R-DRE-426223 Cation influx mediated by TRPC3/6/7 IEA Danio rerio 17815 R-DRE-429786 https://reactome.org/PathwayBrowser/#/R-DRE-429786 SGMS2 transfers phosphocholine onto ceramide IEA Danio rerio 17815 R-DRE-429798 https://reactome.org/PathwayBrowser/#/R-DRE-429798 SGMS1 transfers phosphocholine onto ceramide IEA Danio rerio 17815 R-DRE-5223304 https://reactome.org/PathwayBrowser/#/R-DRE-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Danio rerio 17815 R-DRE-549192 https://reactome.org/PathwayBrowser/#/R-DRE-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Danio rerio 17815 R-DRE-5672965 https://reactome.org/PathwayBrowser/#/R-DRE-5672965 RAS GEFs promote RAS nucleotide exchange IEA Danio rerio 17815 R-DRE-5696074 https://reactome.org/PathwayBrowser/#/R-DRE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Danio rerio 17815 R-DRE-5696448 https://reactome.org/PathwayBrowser/#/R-DRE-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Danio rerio 17815 R-DRE-6800334 https://reactome.org/PathwayBrowser/#/R-DRE-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Danio rerio 17815 R-DRE-75900 https://reactome.org/PathwayBrowser/#/R-DRE-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Danio rerio 17815 R-DRE-8848339 https://reactome.org/PathwayBrowser/#/R-DRE-8848339 PNPLA5 hydrolyzes TAG IEA Danio rerio 17815 R-DRE-8848580 https://reactome.org/PathwayBrowser/#/R-DRE-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Danio rerio 17815 R-DRE-8959462 https://reactome.org/PathwayBrowser/#/R-DRE-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Danio rerio 17815 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus 17815 R-GGA-114553 https://reactome.org/PathwayBrowser/#/R-GGA-114553 Activation of conventional Protein Kinase C IEA Gallus gallus 17815 R-GGA-114683 https://reactome.org/PathwayBrowser/#/R-GGA-114683 Phosphorylation of Platelet Sec-1 IEA Gallus gallus 17815 R-GGA-114688 https://reactome.org/PathwayBrowser/#/R-GGA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Gallus gallus 17815 R-GGA-114689 https://reactome.org/PathwayBrowser/#/R-GGA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Gallus gallus 17815 R-GGA-1168373 https://reactome.org/PathwayBrowser/#/R-GGA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Gallus gallus 17815 R-GGA-1168635 https://reactome.org/PathwayBrowser/#/R-GGA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Gallus gallus 17815 R-GGA-1168636 https://reactome.org/PathwayBrowser/#/R-GGA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Gallus gallus 17815 R-GGA-1482647 https://reactome.org/PathwayBrowser/#/R-GGA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Gallus gallus 17815 R-GGA-1482654 https://reactome.org/PathwayBrowser/#/R-GGA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Gallus gallus 17815 R-GGA-1482777 https://reactome.org/PathwayBrowser/#/R-GGA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Gallus gallus 17815 R-GGA-1482811 https://reactome.org/PathwayBrowser/#/R-GGA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Gallus gallus 17815 R-GGA-1482889 https://reactome.org/PathwayBrowser/#/R-GGA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Gallus gallus 17815 R-GGA-1482961 https://reactome.org/PathwayBrowser/#/R-GGA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Gallus gallus 17815 R-GGA-1482962 https://reactome.org/PathwayBrowser/#/R-GGA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Gallus gallus 17815 R-GGA-1482973 https://reactome.org/PathwayBrowser/#/R-GGA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Gallus gallus 17815 R-GGA-1483203 https://reactome.org/PathwayBrowser/#/R-GGA-1483203 PA is dephosphorylated to DAG by LPIN IEA Gallus gallus 17815 R-GGA-162798 https://reactome.org/PathwayBrowser/#/R-GGA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Gallus gallus 17815 R-GGA-1855177 https://reactome.org/PathwayBrowser/#/R-GGA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Gallus gallus 17815 R-GGA-1855214 https://reactome.org/PathwayBrowser/#/R-GGA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Gallus gallus 17815 R-GGA-1855221 https://reactome.org/PathwayBrowser/#/R-GGA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Gallus gallus 17815 R-GGA-2179413 https://reactome.org/PathwayBrowser/#/R-GGA-2179413 Activated PKC-alpha activate MMP3 IEA Gallus gallus 17815 R-GGA-2750187 https://reactome.org/PathwayBrowser/#/R-GGA-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Gallus gallus 17815 R-GGA-354173 https://reactome.org/PathwayBrowser/#/R-GGA-354173 Activation of Rap1 by cytosolic GEFs IEA Gallus gallus 17815 R-GGA-398193 https://reactome.org/PathwayBrowser/#/R-GGA-398193 PLC beta-mediated PIP2 hydrolysis IEA Gallus gallus 17815 R-GGA-399978 https://reactome.org/PathwayBrowser/#/R-GGA-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Gallus gallus 17815 R-GGA-399998 https://reactome.org/PathwayBrowser/#/R-GGA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Gallus gallus 17815 R-GGA-400015 https://reactome.org/PathwayBrowser/#/R-GGA-400015 Diacylgycerol activates Protein kinase C, alpha type IEA Gallus gallus 17815 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus 17815 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus 17815 R-GGA-425861 https://reactome.org/PathwayBrowser/#/R-GGA-425861 Activation of Protein Kinase C novel isoforms IEA Gallus gallus 17815 R-GGA-426032 https://reactome.org/PathwayBrowser/#/R-GGA-426032 DAG is metabolized by DAGL to 2-AG IEA Gallus gallus 17815 R-GGA-426209 https://reactome.org/PathwayBrowser/#/R-GGA-426209 DAG activation of TRPC channels IEA Gallus gallus 17815 R-GGA-426223 https://reactome.org/PathwayBrowser/#/R-GGA-426223 Cation influx mediated by TRPC3/6/7 IEA Gallus gallus 17815 R-GGA-426240 https://reactome.org/PathwayBrowser/#/R-GGA-426240 DAG kinase produces phosphatidic acid from DAG IEA Gallus gallus 17815 R-GGA-429786 https://reactome.org/PathwayBrowser/#/R-GGA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Gallus gallus 17815 R-GGA-429798 https://reactome.org/PathwayBrowser/#/R-GGA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Gallus gallus 17815 R-GGA-5221130 https://reactome.org/PathwayBrowser/#/R-GGA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Gallus gallus 17815 R-GGA-5223304 https://reactome.org/PathwayBrowser/#/R-GGA-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Gallus gallus 17815 R-GGA-549192 https://reactome.org/PathwayBrowser/#/R-GGA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Gallus gallus 17815 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus 17815 R-GGA-5696074 https://reactome.org/PathwayBrowser/#/R-GGA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Gallus gallus 17815 R-GGA-5696448 https://reactome.org/PathwayBrowser/#/R-GGA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Gallus gallus 17815 R-GGA-6797630 https://reactome.org/PathwayBrowser/#/R-GGA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Gallus gallus 17815 R-GGA-6800334 https://reactome.org/PathwayBrowser/#/R-GGA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Gallus gallus 17815 R-GGA-75899 https://reactome.org/PathwayBrowser/#/R-GGA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Gallus gallus 17815 R-GGA-8848338 https://reactome.org/PathwayBrowser/#/R-GGA-8848338 PNPLA4 hydrolyzes TAG IEA Gallus gallus 17815 R-GGA-8848339 https://reactome.org/PathwayBrowser/#/R-GGA-8848339 PNPLA5 hydrolyzes TAG IEA Gallus gallus 17815 R-GGA-8848580 https://reactome.org/PathwayBrowser/#/R-GGA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Gallus gallus 17815 R-GGA-8934446 https://reactome.org/PathwayBrowser/#/R-GGA-8934446 Activated PKC phosphorylates SHC1 IEA Gallus gallus 17815 R-GGA-8959462 https://reactome.org/PathwayBrowser/#/R-GGA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Gallus gallus 17815 R-HSA-1112666 https://reactome.org/PathwayBrowser/#/R-HSA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate TAS Homo sapiens 17815 R-HSA-114553 https://reactome.org/PathwayBrowser/#/R-HSA-114553 Activation of conventional Protein Kinase C TAS Homo sapiens 17815 R-HSA-114683 https://reactome.org/PathwayBrowser/#/R-HSA-114683 Phosphorylation of Platelet Sec-1 TAS Homo sapiens 17815 R-HSA-114684 https://reactome.org/PathwayBrowser/#/R-HSA-114684 Phosphorylation of Syntaxin-4 TAS Homo sapiens 17815 R-HSA-114688 https://reactome.org/PathwayBrowser/#/R-HSA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 TAS Homo sapiens 17815 R-HSA-114689 https://reactome.org/PathwayBrowser/#/R-HSA-114689 PLC gamma 2-mediated PIP2 hydrolysis TAS Homo sapiens 17815 R-HSA-1168373 https://reactome.org/PathwayBrowser/#/R-HSA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine TAS Homo sapiens 17815 R-HSA-1168374 https://reactome.org/PathwayBrowser/#/R-HSA-1168374 RasGRP1 and RasGRP3 binds diacylglycerol and is phosphorylated IEA Homo sapiens 17815 R-HSA-1168635 https://reactome.org/PathwayBrowser/#/R-HSA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 TAS Homo sapiens 17815 R-HSA-1168636 https://reactome.org/PathwayBrowser/#/R-HSA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP TAS Homo sapiens 17815 R-HSA-1482647 https://reactome.org/PathwayBrowser/#/R-HSA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 TAS Homo sapiens 17815 R-HSA-1482654 https://reactome.org/PathwayBrowser/#/R-HSA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 TAS Homo sapiens 17815 R-HSA-1482777 https://reactome.org/PathwayBrowser/#/R-HSA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 TAS Homo sapiens 17815 R-HSA-1482811 https://reactome.org/PathwayBrowser/#/R-HSA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 TAS Homo sapiens 17815 R-HSA-1482889 https://reactome.org/PathwayBrowser/#/R-HSA-1482889 DAG is acylated to TAG by DGAT1/2 TAS Homo sapiens 17815 R-HSA-1482961 https://reactome.org/PathwayBrowser/#/R-HSA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane TAS Homo sapiens 17815 R-HSA-1482962 https://reactome.org/PathwayBrowser/#/R-HSA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 TAS Homo sapiens 17815 R-HSA-1482973 https://reactome.org/PathwayBrowser/#/R-HSA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane TAS Homo sapiens 17815 R-HSA-1483203 https://reactome.org/PathwayBrowser/#/R-HSA-1483203 PA is dephosphorylated to DAG by LPIN TAS Homo sapiens 17815 R-HSA-162798 https://reactome.org/PathwayBrowser/#/R-HSA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol TAS Homo sapiens 17815 R-HSA-163069 https://reactome.org/PathwayBrowser/#/R-HSA-163069 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol IEA Homo sapiens 17815 R-HSA-163402 https://reactome.org/PathwayBrowser/#/R-HSA-163402 diacylglycerol + H2O -> 2-acylglycerol + fatty acid IEA Homo sapiens 17815 R-HSA-163551 https://reactome.org/PathwayBrowser/#/R-HSA-163551 triacylglycerol + H2O -> diacylglycerol + fatty acid IEA Homo sapiens 17815 R-HSA-1855177 https://reactome.org/PathwayBrowser/#/R-HSA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane TAS Homo sapiens 17815 R-HSA-1855214 https://reactome.org/PathwayBrowser/#/R-HSA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane TAS Homo sapiens 17815 R-HSA-1855221 https://reactome.org/PathwayBrowser/#/R-HSA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane TAS Homo sapiens 17815 R-HSA-2179413 https://reactome.org/PathwayBrowser/#/R-HSA-2179413 Activated PKC-alpha activate MMP3 TAS Homo sapiens 17815 R-HSA-2750187 https://reactome.org/PathwayBrowser/#/R-HSA-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG TAS Homo sapiens 17815 R-HSA-354173 https://reactome.org/PathwayBrowser/#/R-HSA-354173 Activation of Rap1 by cytosolic GEFs TAS Homo sapiens 17815 R-HSA-392831 https://reactome.org/PathwayBrowser/#/R-HSA-392831 Calcium and Diacylglycerol activate CalDAG-GEFs (RasGRPs) IEA Homo sapiens 17815 R-HSA-398193 https://reactome.org/PathwayBrowser/#/R-HSA-398193 PLC beta-mediated PIP2 hydrolysis TAS Homo sapiens 17815 R-HSA-399978 https://reactome.org/PathwayBrowser/#/R-HSA-399978 Protein kinase C, alpha type phosphorylates MARCKS TAS Homo sapiens 17815 R-HSA-399998 https://reactome.org/PathwayBrowser/#/R-HSA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate TAS Homo sapiens 17815 R-HSA-400015 https://reactome.org/PathwayBrowser/#/R-HSA-400015 Diacylgycerol activates Protein kinase C, alpha type TAS Homo sapiens 17815 R-HSA-416639 https://reactome.org/PathwayBrowser/#/R-HSA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites TAS Homo sapiens 17815 R-HSA-421007 https://reactome.org/PathwayBrowser/#/R-HSA-421007 Endocytosis of Ca impermeable AMPA receptors TAS Homo sapiens 17815 R-HSA-425861 https://reactome.org/PathwayBrowser/#/R-HSA-425861 Activation of Protein Kinase C novel isoforms TAS Homo sapiens 17815 R-HSA-426032 https://reactome.org/PathwayBrowser/#/R-HSA-426032 DAG is metabolized by DAGL to 2-AG TAS Homo sapiens 17815 R-HSA-426209 https://reactome.org/PathwayBrowser/#/R-HSA-426209 DAG activation of TRPC channels TAS Homo sapiens 17815 R-HSA-426223 https://reactome.org/PathwayBrowser/#/R-HSA-426223 Cation influx mediated by TRPC3/6/7 TAS Homo sapiens 17815 R-HSA-426240 https://reactome.org/PathwayBrowser/#/R-HSA-426240 DAG kinase produces phosphatidic acid from DAG TAS Homo sapiens 17815 R-HSA-429786 https://reactome.org/PathwayBrowser/#/R-HSA-429786 SGMS2 transfers phosphocholine onto ceramide TAS Homo sapiens 17815 R-HSA-429798 https://reactome.org/PathwayBrowser/#/R-HSA-429798 SGMS1 transfers phosphocholine onto ceramide TAS Homo sapiens 17815 R-HSA-4332390 https://reactome.org/PathwayBrowser/#/R-HSA-4332390 Translocation and activation of PKC alpha in response to WNT signaling IEA Homo sapiens 17815 R-HSA-5138432 https://reactome.org/PathwayBrowser/#/R-HSA-5138432 DVL2 is phosphorylated by PKC TAS Homo sapiens 17815 R-HSA-5221130 https://reactome.org/PathwayBrowser/#/R-HSA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol TAS Homo sapiens 17815 R-HSA-5223304 https://reactome.org/PathwayBrowser/#/R-HSA-5223304 DAG and Ca+2 bind to PKC and tether it to membrane TAS Homo sapiens 17815 R-HSA-5229194 https://reactome.org/PathwayBrowser/#/R-HSA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation TAS Homo sapiens 17815 R-HSA-549192 https://reactome.org/PathwayBrowser/#/R-HSA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] TAS Homo sapiens 17815 R-HSA-5672965 https://reactome.org/PathwayBrowser/#/R-HSA-5672965 RAS GEFs promote RAS nucleotide exchange TAS Homo sapiens 17815 R-HSA-5696074 https://reactome.org/PathwayBrowser/#/R-HSA-5696074 AGK:Mg2+ phosphorylates MAG, DAG TAS Homo sapiens 17815 R-HSA-5696448 https://reactome.org/PathwayBrowser/#/R-HSA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG TAS Homo sapiens 17815 R-HSA-6797630 https://reactome.org/PathwayBrowser/#/R-HSA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA TAS Homo sapiens 17815 R-HSA-6800334 https://reactome.org/PathwayBrowser/#/R-HSA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG TAS Homo sapiens 17815 R-HSA-751040 https://reactome.org/PathwayBrowser/#/R-HSA-751040 PKC phosphorylates G alpha (z) IEA Homo sapiens 17815 R-HSA-75899 https://reactome.org/PathwayBrowser/#/R-HSA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate TAS Homo sapiens 17815 R-HSA-75900 https://reactome.org/PathwayBrowser/#/R-HSA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] TAS Homo sapiens 17815 R-HSA-8848338 https://reactome.org/PathwayBrowser/#/R-HSA-8848338 PNPLA4 hydrolyzes TAG TAS Homo sapiens 17815 R-HSA-8848339 https://reactome.org/PathwayBrowser/#/R-HSA-8848339 PNPLA5 hydrolyzes TAG TAS Homo sapiens 17815 R-HSA-8848580 https://reactome.org/PathwayBrowser/#/R-HSA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG TAS Homo sapiens 17815 R-HSA-8934446 https://reactome.org/PathwayBrowser/#/R-HSA-8934446 Activated PKC phosphorylates SHC1 TAS Homo sapiens 17815 R-HSA-8959462 https://reactome.org/PathwayBrowser/#/R-HSA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER TAS Homo sapiens 17815 R-HSA-8982703 https://reactome.org/PathwayBrowser/#/R-HSA-8982703 PKC binds active G alpha (z) IEA Homo sapiens 17815 R-HSA-8982709 https://reactome.org/PathwayBrowser/#/R-HSA-8982709 G-alpha(z):PKC dissociates to give phosphorylated G alpha (z) IEA Homo sapiens 17815 R-HSA-9717205 https://reactome.org/PathwayBrowser/#/R-HSA-9717205 GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG IEA Homo sapiens 17815 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus 17815 R-MMU-114553 https://reactome.org/PathwayBrowser/#/R-MMU-114553 Activation of conventional Protein Kinase C IEA Mus musculus 17815 R-MMU-114683 https://reactome.org/PathwayBrowser/#/R-MMU-114683 Phosphorylation of Platelet Sec-1 IEA Mus musculus 17815 R-MMU-114684 https://reactome.org/PathwayBrowser/#/R-MMU-114684 Phosphorylation of Syntaxin-4 IEA Mus musculus 17815 R-MMU-114688 https://reactome.org/PathwayBrowser/#/R-MMU-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Mus musculus 17815 R-MMU-114689 https://reactome.org/PathwayBrowser/#/R-MMU-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Mus musculus 17815 R-MMU-1168373 https://reactome.org/PathwayBrowser/#/R-MMU-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Mus musculus 17815 R-MMU-1168635 https://reactome.org/PathwayBrowser/#/R-MMU-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Mus musculus 17815 R-MMU-1168636 https://reactome.org/PathwayBrowser/#/R-MMU-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Mus musculus 17815 R-MMU-1482647 https://reactome.org/PathwayBrowser/#/R-MMU-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Mus musculus 17815 R-MMU-1482654 https://reactome.org/PathwayBrowser/#/R-MMU-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Mus musculus 17815 R-MMU-1482777 https://reactome.org/PathwayBrowser/#/R-MMU-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Mus musculus 17815 R-MMU-1482811 https://reactome.org/PathwayBrowser/#/R-MMU-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Mus musculus 17815 R-MMU-1482889 https://reactome.org/PathwayBrowser/#/R-MMU-1482889 DAG is acylated to TAG by DGAT1/2 IEA Mus musculus 17815 R-MMU-1482961 https://reactome.org/PathwayBrowser/#/R-MMU-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Mus musculus 17815 R-MMU-1482962 https://reactome.org/PathwayBrowser/#/R-MMU-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Mus musculus 17815 R-MMU-1482973 https://reactome.org/PathwayBrowser/#/R-MMU-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Mus musculus 17815 R-MMU-1483203 https://reactome.org/PathwayBrowser/#/R-MMU-1483203 PA is dephosphorylated to DAG by LPIN IEA Mus musculus 17815 R-MMU-162798 https://reactome.org/PathwayBrowser/#/R-MMU-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Mus musculus 17815 R-MMU-162863 https://reactome.org/PathwayBrowser/#/R-MMU-162863 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol TAS Mus musculus 17815 R-MMU-1855177 https://reactome.org/PathwayBrowser/#/R-MMU-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Mus musculus 17815 R-MMU-1855214 https://reactome.org/PathwayBrowser/#/R-MMU-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Mus musculus 17815 R-MMU-1855221 https://reactome.org/PathwayBrowser/#/R-MMU-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Mus musculus 17815 R-MMU-2179413 https://reactome.org/PathwayBrowser/#/R-MMU-2179413 Activated PKC-alpha activate MMP3 IEA Mus musculus 17815 R-MMU-2750187 https://reactome.org/PathwayBrowser/#/R-MMU-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Mus musculus 17815 R-MMU-354173 https://reactome.org/PathwayBrowser/#/R-MMU-354173 Activation of Rap1 by cytosolic GEFs IEA Mus musculus 17815 R-MMU-398193 https://reactome.org/PathwayBrowser/#/R-MMU-398193 PLC beta-mediated PIP2 hydrolysis IEA Mus musculus 17815 R-MMU-399978 https://reactome.org/PathwayBrowser/#/R-MMU-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Mus musculus 17815 R-MMU-399998 https://reactome.org/PathwayBrowser/#/R-MMU-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Mus musculus 17815 R-MMU-400015 https://reactome.org/PathwayBrowser/#/R-MMU-400015 Diacylgycerol activates Protein kinase C, alpha type IEA Mus musculus 17815 R-MMU-416639 https://reactome.org/PathwayBrowser/#/R-MMU-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Mus musculus 17815 R-MMU-421007 https://reactome.org/PathwayBrowser/#/R-MMU-421007 Endocytosis of Ca impermeable AMPA receptors IEA Mus musculus 17815 R-MMU-425861 https://reactome.org/PathwayBrowser/#/R-MMU-425861 Activation of Protein Kinase C novel isoforms IEA Mus musculus 17815 R-MMU-425898 https://reactome.org/PathwayBrowser/#/R-MMU-425898 Calcium and Diacylglycerol activate Ras guanyl-releasing protein 2 TAS Mus musculus 17815 R-MMU-426032 https://reactome.org/PathwayBrowser/#/R-MMU-426032 DAG is metabolized by DAGL to 2-AG IEA Mus musculus 17815 R-MMU-426209 https://reactome.org/PathwayBrowser/#/R-MMU-426209 DAG activation of TRPC channels IEA Mus musculus 17815 R-MMU-426223 https://reactome.org/PathwayBrowser/#/R-MMU-426223 Cation influx mediated by TRPC3/6/7 IEA Mus musculus 17815 R-MMU-426240 https://reactome.org/PathwayBrowser/#/R-MMU-426240 DAG kinase produces phosphatidic acid from DAG IEA Mus musculus 17815 R-MMU-429786 https://reactome.org/PathwayBrowser/#/R-MMU-429786 SGMS2 transfers phosphocholine onto ceramide IEA Mus musculus 17815 R-MMU-429798 https://reactome.org/PathwayBrowser/#/R-MMU-429798 SGMS1 transfers phosphocholine onto ceramide IEA Mus musculus 17815 R-MMU-5138432 https://reactome.org/PathwayBrowser/#/R-MMU-5138432 DVL2 is phosphorylated by PKC IEA Mus musculus 17815 R-MMU-5221130 https://reactome.org/PathwayBrowser/#/R-MMU-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Mus musculus 17815 R-MMU-5223304 https://reactome.org/PathwayBrowser/#/R-MMU-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Mus musculus 17815 R-MMU-5229194 https://reactome.org/PathwayBrowser/#/R-MMU-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Mus musculus 17815 R-MMU-549192 https://reactome.org/PathwayBrowser/#/R-MMU-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Mus musculus 17815 R-MMU-5672965 https://reactome.org/PathwayBrowser/#/R-MMU-5672965 RAS GEFs promote RAS nucleotide exchange IEA Mus musculus 17815 R-MMU-5696074 https://reactome.org/PathwayBrowser/#/R-MMU-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Mus musculus 17815 R-MMU-5696448 https://reactome.org/PathwayBrowser/#/R-MMU-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Mus musculus 17815 R-MMU-6797630 https://reactome.org/PathwayBrowser/#/R-MMU-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Mus musculus 17815 R-MMU-6800334 https://reactome.org/PathwayBrowser/#/R-MMU-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Mus musculus 17815 R-MMU-75899 https://reactome.org/PathwayBrowser/#/R-MMU-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Mus musculus 17815 R-MMU-75900 https://reactome.org/PathwayBrowser/#/R-MMU-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Mus musculus 17815 R-MMU-8848339 https://reactome.org/PathwayBrowser/#/R-MMU-8848339 PNPLA5 hydrolyzes TAG IEA Mus musculus 17815 R-MMU-8848580 https://reactome.org/PathwayBrowser/#/R-MMU-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Mus musculus 17815 R-MMU-8934446 https://reactome.org/PathwayBrowser/#/R-MMU-8934446 Activated PKC phosphorylates SHC1 IEA Mus musculus 17815 R-MMU-8959462 https://reactome.org/PathwayBrowser/#/R-MMU-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Mus musculus 17815 R-MMU-9682158 https://reactome.org/PathwayBrowser/#/R-MMU-9682158 Csf1r-associated Plcg2 hydrolyzes phosphatidylcholine yielding choline phosphate and 1,2-diacylglycerol TAS Mus musculus 17815 R-NUL-804924 https://reactome.org/PathwayBrowser/#/R-NUL-804924 PKC (cow) phosphorylates G alpha z (rat) TAS Bos taurus 17815 R-NUL-8982704 https://reactome.org/PathwayBrowser/#/R-NUL-8982704 PKC (cow) binds G alpha z (rat) TAS Bos taurus 17815 R-NUL-8982712 https://reactome.org/PathwayBrowser/#/R-NUL-8982712 Gz(rat):PKC(cow) dissociates to give phosphorylated G alpha (z) TAS Bos taurus 17815 R-NUL-9717576 https://reactome.org/PathwayBrowser/#/R-NUL-9717576 Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG TAS Bos taurus 17815 R-PFA-114689 https://reactome.org/PathwayBrowser/#/R-PFA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Plasmodium falciparum 17815 R-PFA-1482647 https://reactome.org/PathwayBrowser/#/R-PFA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Plasmodium falciparum 17815 R-PFA-1482654 https://reactome.org/PathwayBrowser/#/R-PFA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Plasmodium falciparum 17815 R-PFA-1482777 https://reactome.org/PathwayBrowser/#/R-PFA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Plasmodium falciparum 17815 R-PFA-1482811 https://reactome.org/PathwayBrowser/#/R-PFA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Plasmodium falciparum 17815 R-PFA-1482889 https://reactome.org/PathwayBrowser/#/R-PFA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Plasmodium falciparum 17815 R-PFA-1482961 https://reactome.org/PathwayBrowser/#/R-PFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Plasmodium falciparum 17815 R-PFA-1482962 https://reactome.org/PathwayBrowser/#/R-PFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Plasmodium falciparum 17815 R-PFA-1482973 https://reactome.org/PathwayBrowser/#/R-PFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Plasmodium falciparum 17815 R-PFA-1483203 https://reactome.org/PathwayBrowser/#/R-PFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Plasmodium falciparum 17815 R-PFA-1855177 https://reactome.org/PathwayBrowser/#/R-PFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Plasmodium falciparum 17815 R-PFA-1855214 https://reactome.org/PathwayBrowser/#/R-PFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Plasmodium falciparum 17815 R-PFA-1855221 https://reactome.org/PathwayBrowser/#/R-PFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Plasmodium falciparum 17815 R-PFA-426240 https://reactome.org/PathwayBrowser/#/R-PFA-426240 DAG kinase produces phosphatidic acid from DAG IEA Plasmodium falciparum 17815 R-PFA-429786 https://reactome.org/PathwayBrowser/#/R-PFA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Plasmodium falciparum 17815 R-PFA-429798 https://reactome.org/PathwayBrowser/#/R-PFA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Plasmodium falciparum 17815 R-PFA-5221130 https://reactome.org/PathwayBrowser/#/R-PFA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Plasmodium falciparum 17815 R-PFA-75899 https://reactome.org/PathwayBrowser/#/R-PFA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Plasmodium falciparum 17815 R-PFA-75900 https://reactome.org/PathwayBrowser/#/R-PFA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Plasmodium falciparum 17815 R-PFA-8848338 https://reactome.org/PathwayBrowser/#/R-PFA-8848338 PNPLA4 hydrolyzes TAG IEA Plasmodium falciparum 17815 R-PFA-8848339 https://reactome.org/PathwayBrowser/#/R-PFA-8848339 PNPLA5 hydrolyzes TAG IEA Plasmodium falciparum 17815 R-PFA-8959462 https://reactome.org/PathwayBrowser/#/R-PFA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Plasmodium falciparum 17815 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus 17815 R-RNO-114553 https://reactome.org/PathwayBrowser/#/R-RNO-114553 Activation of conventional Protein Kinase C IEA Rattus norvegicus 17815 R-RNO-114683 https://reactome.org/PathwayBrowser/#/R-RNO-114683 Phosphorylation of Platelet Sec-1 IEA Rattus norvegicus 17815 R-RNO-114684 https://reactome.org/PathwayBrowser/#/R-RNO-114684 Phosphorylation of Syntaxin-4 IEA Rattus norvegicus 17815 R-RNO-114688 https://reactome.org/PathwayBrowser/#/R-RNO-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Rattus norvegicus 17815 R-RNO-114689 https://reactome.org/PathwayBrowser/#/R-RNO-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Rattus norvegicus 17815 R-RNO-1168373 https://reactome.org/PathwayBrowser/#/R-RNO-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Rattus norvegicus 17815 R-RNO-1168635 https://reactome.org/PathwayBrowser/#/R-RNO-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Rattus norvegicus 17815 R-RNO-1168636 https://reactome.org/PathwayBrowser/#/R-RNO-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Rattus norvegicus 17815 R-RNO-1482647 https://reactome.org/PathwayBrowser/#/R-RNO-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Rattus norvegicus 17815 R-RNO-1482654 https://reactome.org/PathwayBrowser/#/R-RNO-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Rattus norvegicus 17815 R-RNO-1482777 https://reactome.org/PathwayBrowser/#/R-RNO-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Rattus norvegicus 17815 R-RNO-1482811 https://reactome.org/PathwayBrowser/#/R-RNO-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Rattus norvegicus 17815 R-RNO-1482889 https://reactome.org/PathwayBrowser/#/R-RNO-1482889 DAG is acylated to TAG by DGAT1/2 IEA Rattus norvegicus 17815 R-RNO-1482961 https://reactome.org/PathwayBrowser/#/R-RNO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Rattus norvegicus 17815 R-RNO-1482962 https://reactome.org/PathwayBrowser/#/R-RNO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Rattus norvegicus 17815 R-RNO-1482973 https://reactome.org/PathwayBrowser/#/R-RNO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Rattus norvegicus 17815 R-RNO-1483203 https://reactome.org/PathwayBrowser/#/R-RNO-1483203 PA is dephosphorylated to DAG by LPIN IEA Rattus norvegicus 17815 R-RNO-162798 https://reactome.org/PathwayBrowser/#/R-RNO-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Rattus norvegicus 17815 R-RNO-163440 https://reactome.org/PathwayBrowser/#/R-RNO-163440 diacylglycerol + H2O -> 2-acylglycerol + fatty acid TAS Rattus norvegicus 17815 R-RNO-163515 https://reactome.org/PathwayBrowser/#/R-RNO-163515 triacylglycerol + H2O -> diacylglycerol + fatty acid TAS Rattus norvegicus 17815 R-RNO-1855177 https://reactome.org/PathwayBrowser/#/R-RNO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Rattus norvegicus 17815 R-RNO-1855214 https://reactome.org/PathwayBrowser/#/R-RNO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Rattus norvegicus 17815 R-RNO-1855221 https://reactome.org/PathwayBrowser/#/R-RNO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Rattus norvegicus 17815 R-RNO-2179413 https://reactome.org/PathwayBrowser/#/R-RNO-2179413 Activated PKC-alpha activate MMP3 IEA Rattus norvegicus 17815 R-RNO-2750187 https://reactome.org/PathwayBrowser/#/R-RNO-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Rattus norvegicus 17815 R-RNO-354173 https://reactome.org/PathwayBrowser/#/R-RNO-354173 Activation of Rap1 by cytosolic GEFs IEA Rattus norvegicus 17815 R-RNO-399978 https://reactome.org/PathwayBrowser/#/R-RNO-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Rattus norvegicus 17815 R-RNO-399998 https://reactome.org/PathwayBrowser/#/R-RNO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Rattus norvegicus 17815 R-RNO-400015 https://reactome.org/PathwayBrowser/#/R-RNO-400015 Diacylgycerol activates Protein kinase C, alpha type IEA Rattus norvegicus 17815 R-RNO-416639 https://reactome.org/PathwayBrowser/#/R-RNO-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Rattus norvegicus 17815 R-RNO-421007 https://reactome.org/PathwayBrowser/#/R-RNO-421007 Endocytosis of Ca impermeable AMPA receptors IEA Rattus norvegicus 17815 R-RNO-425861 https://reactome.org/PathwayBrowser/#/R-RNO-425861 Activation of Protein Kinase C novel isoforms IEA Rattus norvegicus 17815 R-RNO-426032 https://reactome.org/PathwayBrowser/#/R-RNO-426032 DAG is metabolized by DAGL to 2-AG IEA Rattus norvegicus 17815 R-RNO-426209 https://reactome.org/PathwayBrowser/#/R-RNO-426209 DAG activation of TRPC channels IEA Rattus norvegicus 17815 R-RNO-426223 https://reactome.org/PathwayBrowser/#/R-RNO-426223 Cation influx mediated by TRPC3/6/7 IEA Rattus norvegicus 17815 R-RNO-426240 https://reactome.org/PathwayBrowser/#/R-RNO-426240 DAG kinase produces phosphatidic acid from DAG IEA Rattus norvegicus 17815 R-RNO-429786 https://reactome.org/PathwayBrowser/#/R-RNO-429786 SGMS2 transfers phosphocholine onto ceramide IEA Rattus norvegicus 17815 R-RNO-429798 https://reactome.org/PathwayBrowser/#/R-RNO-429798 SGMS1 transfers phosphocholine onto ceramide IEA Rattus norvegicus 17815 R-RNO-5138432 https://reactome.org/PathwayBrowser/#/R-RNO-5138432 DVL2 is phosphorylated by PKC IEA Rattus norvegicus 17815 R-RNO-5221130 https://reactome.org/PathwayBrowser/#/R-RNO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Rattus norvegicus 17815 R-RNO-5223304 https://reactome.org/PathwayBrowser/#/R-RNO-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Rattus norvegicus 17815 R-RNO-5229194 https://reactome.org/PathwayBrowser/#/R-RNO-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Rattus norvegicus 17815 R-RNO-549192 https://reactome.org/PathwayBrowser/#/R-RNO-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Rattus norvegicus 17815 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus 17815 R-RNO-5696074 https://reactome.org/PathwayBrowser/#/R-RNO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Rattus norvegicus 17815 R-RNO-5696448 https://reactome.org/PathwayBrowser/#/R-RNO-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Rattus norvegicus 17815 R-RNO-6797630 https://reactome.org/PathwayBrowser/#/R-RNO-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Rattus norvegicus 17815 R-RNO-6800334 https://reactome.org/PathwayBrowser/#/R-RNO-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Rattus norvegicus 17815 R-RNO-75899 https://reactome.org/PathwayBrowser/#/R-RNO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Rattus norvegicus 17815 R-RNO-75900 https://reactome.org/PathwayBrowser/#/R-RNO-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Rattus norvegicus 17815 R-RNO-8848338 https://reactome.org/PathwayBrowser/#/R-RNO-8848338 PNPLA4 hydrolyzes TAG IEA Rattus norvegicus 17815 R-RNO-8848339 https://reactome.org/PathwayBrowser/#/R-RNO-8848339 PNPLA5 hydrolyzes TAG IEA Rattus norvegicus 17815 R-RNO-8848580 https://reactome.org/PathwayBrowser/#/R-RNO-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Rattus norvegicus 17815 R-RNO-8934446 https://reactome.org/PathwayBrowser/#/R-RNO-8934446 Activated PKC phosphorylates SHC1 IEA Rattus norvegicus 17815 R-RNO-8959462 https://reactome.org/PathwayBrowser/#/R-RNO-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Rattus norvegicus 17815 R-SCE-114553 https://reactome.org/PathwayBrowser/#/R-SCE-114553 Activation of conventional Protein Kinase C IEA Saccharomyces cerevisiae 17815 R-SCE-114683 https://reactome.org/PathwayBrowser/#/R-SCE-114683 Phosphorylation of Platelet Sec-1 IEA Saccharomyces cerevisiae 17815 R-SCE-114684 https://reactome.org/PathwayBrowser/#/R-SCE-114684 Phosphorylation of Syntaxin-4 IEA Saccharomyces cerevisiae 17815 R-SCE-114688 https://reactome.org/PathwayBrowser/#/R-SCE-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Saccharomyces cerevisiae 17815 R-SCE-114689 https://reactome.org/PathwayBrowser/#/R-SCE-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Saccharomyces cerevisiae 17815 R-SCE-1168373 https://reactome.org/PathwayBrowser/#/R-SCE-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Saccharomyces cerevisiae 17815 R-SCE-1482889 https://reactome.org/PathwayBrowser/#/R-SCE-1482889 DAG is acylated to TAG by DGAT1/2 IEA Saccharomyces cerevisiae 17815 R-SCE-1482961 https://reactome.org/PathwayBrowser/#/R-SCE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Saccharomyces cerevisiae 17815 R-SCE-1482962 https://reactome.org/PathwayBrowser/#/R-SCE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Saccharomyces cerevisiae 17815 R-SCE-1482973 https://reactome.org/PathwayBrowser/#/R-SCE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Saccharomyces cerevisiae 17815 R-SCE-1483203 https://reactome.org/PathwayBrowser/#/R-SCE-1483203 PA is dephosphorylated to DAG by LPIN IEA Saccharomyces cerevisiae 17815 R-SCE-162798 https://reactome.org/PathwayBrowser/#/R-SCE-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Saccharomyces cerevisiae 17815 R-SCE-1855177 https://reactome.org/PathwayBrowser/#/R-SCE-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Saccharomyces cerevisiae 17815 R-SCE-1855214 https://reactome.org/PathwayBrowser/#/R-SCE-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Saccharomyces cerevisiae 17815 R-SCE-1855221 https://reactome.org/PathwayBrowser/#/R-SCE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Saccharomyces cerevisiae 17815 R-SCE-354173 https://reactome.org/PathwayBrowser/#/R-SCE-354173 Activation of Rap1 by cytosolic GEFs IEA Saccharomyces cerevisiae 17815 R-SCE-399998 https://reactome.org/PathwayBrowser/#/R-SCE-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Saccharomyces cerevisiae 17815 R-SCE-400015 https://reactome.org/PathwayBrowser/#/R-SCE-400015 Diacylgycerol activates Protein kinase C, alpha type IEA Saccharomyces cerevisiae 17815 R-SCE-425861 https://reactome.org/PathwayBrowser/#/R-SCE-425861 Activation of Protein Kinase C novel isoforms IEA Saccharomyces cerevisiae 17815 R-SCE-5221130 https://reactome.org/PathwayBrowser/#/R-SCE-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Saccharomyces cerevisiae 17815 R-SCE-5223304 https://reactome.org/PathwayBrowser/#/R-SCE-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Saccharomyces cerevisiae 17815 R-SCE-549192 https://reactome.org/PathwayBrowser/#/R-SCE-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Saccharomyces cerevisiae 17815 R-SCE-5696074 https://reactome.org/PathwayBrowser/#/R-SCE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Saccharomyces cerevisiae 17815 R-SCE-5696448 https://reactome.org/PathwayBrowser/#/R-SCE-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Saccharomyces cerevisiae 17815 R-SCE-6797630 https://reactome.org/PathwayBrowser/#/R-SCE-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Saccharomyces cerevisiae 17815 R-SCE-6800334 https://reactome.org/PathwayBrowser/#/R-SCE-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Saccharomyces cerevisiae 17815 R-SCE-75899 https://reactome.org/PathwayBrowser/#/R-SCE-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Saccharomyces cerevisiae 17815 R-SCE-8848580 https://reactome.org/PathwayBrowser/#/R-SCE-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Saccharomyces cerevisiae 17815 R-SPO-114553 https://reactome.org/PathwayBrowser/#/R-SPO-114553 Activation of conventional Protein Kinase C IEA Schizosaccharomyces pombe 17815 R-SPO-114683 https://reactome.org/PathwayBrowser/#/R-SPO-114683 Phosphorylation of Platelet Sec-1 IEA Schizosaccharomyces pombe 17815 R-SPO-114684 https://reactome.org/PathwayBrowser/#/R-SPO-114684 Phosphorylation of Syntaxin-4 IEA Schizosaccharomyces pombe 17815 R-SPO-114688 https://reactome.org/PathwayBrowser/#/R-SPO-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Schizosaccharomyces pombe 17815 R-SPO-114689 https://reactome.org/PathwayBrowser/#/R-SPO-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Schizosaccharomyces pombe 17815 R-SPO-1168373 https://reactome.org/PathwayBrowser/#/R-SPO-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Schizosaccharomyces pombe 17815 R-SPO-1482889 https://reactome.org/PathwayBrowser/#/R-SPO-1482889 DAG is acylated to TAG by DGAT1/2 IEA Schizosaccharomyces pombe 17815 R-SPO-1482961 https://reactome.org/PathwayBrowser/#/R-SPO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Schizosaccharomyces pombe 17815 R-SPO-1482962 https://reactome.org/PathwayBrowser/#/R-SPO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Schizosaccharomyces pombe 17815 R-SPO-1482973 https://reactome.org/PathwayBrowser/#/R-SPO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Schizosaccharomyces pombe 17815 R-SPO-1483203 https://reactome.org/PathwayBrowser/#/R-SPO-1483203 PA is dephosphorylated to DAG by LPIN IEA Schizosaccharomyces pombe 17815 R-SPO-162798 https://reactome.org/PathwayBrowser/#/R-SPO-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Schizosaccharomyces pombe 17815 R-SPO-1855177 https://reactome.org/PathwayBrowser/#/R-SPO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Schizosaccharomyces pombe 17815 R-SPO-1855214 https://reactome.org/PathwayBrowser/#/R-SPO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Schizosaccharomyces pombe 17815 R-SPO-1855221 https://reactome.org/PathwayBrowser/#/R-SPO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Schizosaccharomyces pombe 17815 R-SPO-399998 https://reactome.org/PathwayBrowser/#/R-SPO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Schizosaccharomyces pombe 17815 R-SPO-400015 https://reactome.org/PathwayBrowser/#/R-SPO-400015 Diacylgycerol activates Protein kinase C, alpha type IEA Schizosaccharomyces pombe 17815 R-SPO-425861 https://reactome.org/PathwayBrowser/#/R-SPO-425861 Activation of Protein Kinase C novel isoforms IEA Schizosaccharomyces pombe 17815 R-SPO-5221130 https://reactome.org/PathwayBrowser/#/R-SPO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Schizosaccharomyces pombe 17815 R-SPO-5223304 https://reactome.org/PathwayBrowser/#/R-SPO-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Schizosaccharomyces pombe 17815 R-SPO-549192 https://reactome.org/PathwayBrowser/#/R-SPO-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Schizosaccharomyces pombe 17815 R-SPO-5696074 https://reactome.org/PathwayBrowser/#/R-SPO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Schizosaccharomyces pombe 17815 R-SPO-5696448 https://reactome.org/PathwayBrowser/#/R-SPO-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Schizosaccharomyces pombe 17815 R-SPO-6797630 https://reactome.org/PathwayBrowser/#/R-SPO-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Schizosaccharomyces pombe 17815 R-SPO-6800334 https://reactome.org/PathwayBrowser/#/R-SPO-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Schizosaccharomyces pombe 17815 R-SPO-75899 https://reactome.org/PathwayBrowser/#/R-SPO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Schizosaccharomyces pombe 17815 R-SPO-8848580 https://reactome.org/PathwayBrowser/#/R-SPO-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Schizosaccharomyces pombe 17815 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa 17815 R-SSC-114553 https://reactome.org/PathwayBrowser/#/R-SSC-114553 Activation of conventional Protein Kinase C IEA Sus scrofa 17815 R-SSC-114683 https://reactome.org/PathwayBrowser/#/R-SSC-114683 Phosphorylation of Platelet Sec-1 IEA Sus scrofa 17815 R-SSC-114684 https://reactome.org/PathwayBrowser/#/R-SSC-114684 Phosphorylation of Syntaxin-4 IEA Sus scrofa 17815 R-SSC-114688 https://reactome.org/PathwayBrowser/#/R-SSC-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Sus scrofa 17815 R-SSC-114689 https://reactome.org/PathwayBrowser/#/R-SSC-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Sus scrofa 17815 R-SSC-1168636 https://reactome.org/PathwayBrowser/#/R-SSC-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Sus scrofa 17815 R-SSC-1482647 https://reactome.org/PathwayBrowser/#/R-SSC-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Sus scrofa 17815 R-SSC-1482654 https://reactome.org/PathwayBrowser/#/R-SSC-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Sus scrofa 17815 R-SSC-1482777 https://reactome.org/PathwayBrowser/#/R-SSC-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Sus scrofa 17815 R-SSC-1482811 https://reactome.org/PathwayBrowser/#/R-SSC-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Sus scrofa 17815 R-SSC-1482889 https://reactome.org/PathwayBrowser/#/R-SSC-1482889 DAG is acylated to TAG by DGAT1/2 IEA Sus scrofa 17815 R-SSC-1482961 https://reactome.org/PathwayBrowser/#/R-SSC-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Sus scrofa 17815 R-SSC-1482962 https://reactome.org/PathwayBrowser/#/R-SSC-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Sus scrofa 17815 R-SSC-1482973 https://reactome.org/PathwayBrowser/#/R-SSC-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Sus scrofa 17815 R-SSC-1483203 https://reactome.org/PathwayBrowser/#/R-SSC-1483203 PA is dephosphorylated to DAG by LPIN IEA Sus scrofa 17815 R-SSC-162798 https://reactome.org/PathwayBrowser/#/R-SSC-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Sus scrofa 17815 R-SSC-1855177 https://reactome.org/PathwayBrowser/#/R-SSC-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Sus scrofa 17815 R-SSC-1855214 https://reactome.org/PathwayBrowser/#/R-SSC-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Sus scrofa 17815 R-SSC-1855221 https://reactome.org/PathwayBrowser/#/R-SSC-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Sus scrofa 17815 R-SSC-2179413 https://reactome.org/PathwayBrowser/#/R-SSC-2179413 Activated PKC-alpha activate MMP3 IEA Sus scrofa 17815 R-SSC-2750187 https://reactome.org/PathwayBrowser/#/R-SSC-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Sus scrofa 17815 R-SSC-354173 https://reactome.org/PathwayBrowser/#/R-SSC-354173 Activation of Rap1 by cytosolic GEFs IEA Sus scrofa 17815 R-SSC-398193 https://reactome.org/PathwayBrowser/#/R-SSC-398193 PLC beta-mediated PIP2 hydrolysis IEA Sus scrofa 17815 R-SSC-399978 https://reactome.org/PathwayBrowser/#/R-SSC-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Sus scrofa 17815 R-SSC-399998 https://reactome.org/PathwayBrowser/#/R-SSC-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Sus scrofa 17815 R-SSC-400015 https://reactome.org/PathwayBrowser/#/R-SSC-400015 Diacylgycerol activates Protein kinase C, alpha type IEA Sus scrofa 17815 R-SSC-416639 https://reactome.org/PathwayBrowser/#/R-SSC-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Sus scrofa 17815 R-SSC-421007 https://reactome.org/PathwayBrowser/#/R-SSC-421007 Endocytosis of Ca impermeable AMPA receptors IEA Sus scrofa 17815 R-SSC-425861 https://reactome.org/PathwayBrowser/#/R-SSC-425861 Activation of Protein Kinase C novel isoforms IEA Sus scrofa 17815 R-SSC-426032 https://reactome.org/PathwayBrowser/#/R-SSC-426032 DAG is metabolized by DAGL to 2-AG IEA Sus scrofa 17815 R-SSC-426209 https://reactome.org/PathwayBrowser/#/R-SSC-426209 DAG activation of TRPC channels IEA Sus scrofa 17815 R-SSC-426223 https://reactome.org/PathwayBrowser/#/R-SSC-426223 Cation influx mediated by TRPC3/6/7 IEA Sus scrofa 17815 R-SSC-426240 https://reactome.org/PathwayBrowser/#/R-SSC-426240 DAG kinase produces phosphatidic acid from DAG IEA Sus scrofa 17815 R-SSC-429786 https://reactome.org/PathwayBrowser/#/R-SSC-429786 SGMS2 transfers phosphocholine onto ceramide IEA Sus scrofa 17815 R-SSC-429798 https://reactome.org/PathwayBrowser/#/R-SSC-429798 SGMS1 transfers phosphocholine onto ceramide IEA Sus scrofa 17815 R-SSC-5138432 https://reactome.org/PathwayBrowser/#/R-SSC-5138432 DVL2 is phosphorylated by PKC IEA Sus scrofa 17815 R-SSC-5221130 https://reactome.org/PathwayBrowser/#/R-SSC-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Sus scrofa 17815 R-SSC-5223304 https://reactome.org/PathwayBrowser/#/R-SSC-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Sus scrofa 17815 R-SSC-5229194 https://reactome.org/PathwayBrowser/#/R-SSC-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Sus scrofa 17815 R-SSC-549192 https://reactome.org/PathwayBrowser/#/R-SSC-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Sus scrofa 17815 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa 17815 R-SSC-5696074 https://reactome.org/PathwayBrowser/#/R-SSC-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Sus scrofa 17815 R-SSC-5696448 https://reactome.org/PathwayBrowser/#/R-SSC-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Sus scrofa 17815 R-SSC-6797630 https://reactome.org/PathwayBrowser/#/R-SSC-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Sus scrofa 17815 R-SSC-6800334 https://reactome.org/PathwayBrowser/#/R-SSC-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Sus scrofa 17815 R-SSC-75899 https://reactome.org/PathwayBrowser/#/R-SSC-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Sus scrofa 17815 R-SSC-75900 https://reactome.org/PathwayBrowser/#/R-SSC-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Sus scrofa 17815 R-SSC-8848338 https://reactome.org/PathwayBrowser/#/R-SSC-8848338 PNPLA4 hydrolyzes TAG IEA Sus scrofa 17815 R-SSC-8848580 https://reactome.org/PathwayBrowser/#/R-SSC-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Sus scrofa 17815 R-SSC-8934446 https://reactome.org/PathwayBrowser/#/R-SSC-8934446 Activated PKC phosphorylates SHC1 IEA Sus scrofa 17815 R-SSC-8959462 https://reactome.org/PathwayBrowser/#/R-SSC-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Sus scrofa 17815 R-XLA-4332392 https://reactome.org/PathwayBrowser/#/R-XLA-4332392 translocation of Xenopus prkca to plasma membrane TAS Xenopus laevis 17815 R-XTR-114553 https://reactome.org/PathwayBrowser/#/R-XTR-114553 Activation of conventional Protein Kinase C IEA Xenopus tropicalis 17815 R-XTR-114683 https://reactome.org/PathwayBrowser/#/R-XTR-114683 Phosphorylation of Platelet Sec-1 IEA Xenopus tropicalis 17815 R-XTR-114684 https://reactome.org/PathwayBrowser/#/R-XTR-114684 Phosphorylation of Syntaxin-4 IEA Xenopus tropicalis 17815 R-XTR-114688 https://reactome.org/PathwayBrowser/#/R-XTR-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Xenopus tropicalis 17815 R-XTR-114689 https://reactome.org/PathwayBrowser/#/R-XTR-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Xenopus tropicalis 17815 R-XTR-1168373 https://reactome.org/PathwayBrowser/#/R-XTR-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Xenopus tropicalis 17815 R-XTR-1168635 https://reactome.org/PathwayBrowser/#/R-XTR-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Xenopus tropicalis 17815 R-XTR-1168636 https://reactome.org/PathwayBrowser/#/R-XTR-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Xenopus tropicalis 17815 R-XTR-1482647 https://reactome.org/PathwayBrowser/#/R-XTR-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Xenopus tropicalis 17815 R-XTR-1482654 https://reactome.org/PathwayBrowser/#/R-XTR-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Xenopus tropicalis 17815 R-XTR-1482777 https://reactome.org/PathwayBrowser/#/R-XTR-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Xenopus tropicalis 17815 R-XTR-1482811 https://reactome.org/PathwayBrowser/#/R-XTR-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Xenopus tropicalis 17815 R-XTR-1482889 https://reactome.org/PathwayBrowser/#/R-XTR-1482889 DAG is acylated to TAG by DGAT1/2 IEA Xenopus tropicalis 17815 R-XTR-1482961 https://reactome.org/PathwayBrowser/#/R-XTR-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Xenopus tropicalis 17815 R-XTR-1482962 https://reactome.org/PathwayBrowser/#/R-XTR-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Xenopus tropicalis 17815 R-XTR-1482973 https://reactome.org/PathwayBrowser/#/R-XTR-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Xenopus tropicalis 17815 R-XTR-1483203 https://reactome.org/PathwayBrowser/#/R-XTR-1483203 PA is dephosphorylated to DAG by LPIN IEA Xenopus tropicalis 17815 R-XTR-162798 https://reactome.org/PathwayBrowser/#/R-XTR-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Xenopus tropicalis 17815 R-XTR-1855177 https://reactome.org/PathwayBrowser/#/R-XTR-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Xenopus tropicalis 17815 R-XTR-1855214 https://reactome.org/PathwayBrowser/#/R-XTR-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Xenopus tropicalis 17815 R-XTR-1855221 https://reactome.org/PathwayBrowser/#/R-XTR-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Xenopus tropicalis 17815 R-XTR-354173 https://reactome.org/PathwayBrowser/#/R-XTR-354173 Activation of Rap1 by cytosolic GEFs IEA Xenopus tropicalis 17815 R-XTR-398193 https://reactome.org/PathwayBrowser/#/R-XTR-398193 PLC beta-mediated PIP2 hydrolysis IEA Xenopus tropicalis 17815 R-XTR-425861 https://reactome.org/PathwayBrowser/#/R-XTR-425861 Activation of Protein Kinase C novel isoforms IEA Xenopus tropicalis 17815 R-XTR-426032 https://reactome.org/PathwayBrowser/#/R-XTR-426032 DAG is metabolized by DAGL to 2-AG IEA Xenopus tropicalis 17815 R-XTR-426209 https://reactome.org/PathwayBrowser/#/R-XTR-426209 DAG activation of TRPC channels IEA Xenopus tropicalis 17815 R-XTR-426223 https://reactome.org/PathwayBrowser/#/R-XTR-426223 Cation influx mediated by TRPC3/6/7 IEA Xenopus tropicalis 17815 R-XTR-426240 https://reactome.org/PathwayBrowser/#/R-XTR-426240 DAG kinase produces phosphatidic acid from DAG IEA Xenopus tropicalis 17815 R-XTR-429786 https://reactome.org/PathwayBrowser/#/R-XTR-429786 SGMS2 transfers phosphocholine onto ceramide IEA Xenopus tropicalis 17815 R-XTR-429798 https://reactome.org/PathwayBrowser/#/R-XTR-429798 SGMS1 transfers phosphocholine onto ceramide IEA Xenopus tropicalis 17815 R-XTR-5138432 https://reactome.org/PathwayBrowser/#/R-XTR-5138432 DVL2 is phosphorylated by PKC IEA Xenopus tropicalis 17815 R-XTR-5221130 https://reactome.org/PathwayBrowser/#/R-XTR-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Xenopus tropicalis 17815 R-XTR-5223304 https://reactome.org/PathwayBrowser/#/R-XTR-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Xenopus tropicalis 17815 R-XTR-5229194 https://reactome.org/PathwayBrowser/#/R-XTR-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Xenopus tropicalis 17815 R-XTR-549192 https://reactome.org/PathwayBrowser/#/R-XTR-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Xenopus tropicalis 17815 R-XTR-5672965 https://reactome.org/PathwayBrowser/#/R-XTR-5672965 RAS GEFs promote RAS nucleotide exchange IEA Xenopus tropicalis 17815 R-XTR-5696074 https://reactome.org/PathwayBrowser/#/R-XTR-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Xenopus tropicalis 17815 R-XTR-5696448 https://reactome.org/PathwayBrowser/#/R-XTR-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Xenopus tropicalis 17815 R-XTR-6797630 https://reactome.org/PathwayBrowser/#/R-XTR-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Xenopus tropicalis 17815 R-XTR-6800334 https://reactome.org/PathwayBrowser/#/R-XTR-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Xenopus tropicalis 17815 R-XTR-75899 https://reactome.org/PathwayBrowser/#/R-XTR-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Xenopus tropicalis 17815 R-XTR-75900 https://reactome.org/PathwayBrowser/#/R-XTR-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Xenopus tropicalis 17815 R-XTR-8848338 https://reactome.org/PathwayBrowser/#/R-XTR-8848338 PNPLA4 hydrolyzes TAG IEA Xenopus tropicalis 17815 R-XTR-8848339 https://reactome.org/PathwayBrowser/#/R-XTR-8848339 PNPLA5 hydrolyzes TAG IEA Xenopus tropicalis 17815 R-XTR-8848580 https://reactome.org/PathwayBrowser/#/R-XTR-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Xenopus tropicalis 17815 R-XTR-8959462 https://reactome.org/PathwayBrowser/#/R-XTR-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Xenopus tropicalis 17816 R-BTA-1855174 https://reactome.org/PathwayBrowser/#/R-BTA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Bos taurus 17816 R-BTA-1855208 https://reactome.org/PathwayBrowser/#/R-BTA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Bos taurus 17816 R-BTA-1855222 https://reactome.org/PathwayBrowser/#/R-BTA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Bos taurus 17816 R-CEL-1855174 https://reactome.org/PathwayBrowser/#/R-CEL-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Caenorhabditis elegans 17816 R-CEL-1855222 https://reactome.org/PathwayBrowser/#/R-CEL-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Caenorhabditis elegans 17816 R-CFA-1855174 https://reactome.org/PathwayBrowser/#/R-CFA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Canis familiaris 17816 R-CFA-1855208 https://reactome.org/PathwayBrowser/#/R-CFA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Canis familiaris 17816 R-CFA-1855222 https://reactome.org/PathwayBrowser/#/R-CFA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Canis familiaris 17816 R-DDI-1855174 https://reactome.org/PathwayBrowser/#/R-DDI-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Dictyostelium discoideum 17816 R-DDI-1855208 https://reactome.org/PathwayBrowser/#/R-DDI-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Dictyostelium discoideum 17816 R-DDI-1855222 https://reactome.org/PathwayBrowser/#/R-DDI-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Dictyostelium discoideum 17816 R-DME-1855174 https://reactome.org/PathwayBrowser/#/R-DME-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Drosophila melanogaster 17816 R-DME-1855208 https://reactome.org/PathwayBrowser/#/R-DME-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Drosophila melanogaster 17816 R-DME-1855222 https://reactome.org/PathwayBrowser/#/R-DME-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Drosophila melanogaster 17816 R-DRE-1855222 https://reactome.org/PathwayBrowser/#/R-DRE-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Danio rerio 17816 R-GGA-1855174 https://reactome.org/PathwayBrowser/#/R-GGA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Gallus gallus 17816 R-GGA-1855208 https://reactome.org/PathwayBrowser/#/R-GGA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Gallus gallus 17816 R-GGA-1855222 https://reactome.org/PathwayBrowser/#/R-GGA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Gallus gallus 17816 R-HSA-1855174 https://reactome.org/PathwayBrowser/#/R-HSA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol TAS Homo sapiens 17816 R-HSA-1855208 https://reactome.org/PathwayBrowser/#/R-HSA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol TAS Homo sapiens 17816 R-HSA-1855222 https://reactome.org/PathwayBrowser/#/R-HSA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane TAS Homo sapiens 17816 R-MMU-1855174 https://reactome.org/PathwayBrowser/#/R-MMU-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Mus musculus 17816 R-MMU-1855208 https://reactome.org/PathwayBrowser/#/R-MMU-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Mus musculus 17816 R-MMU-1855222 https://reactome.org/PathwayBrowser/#/R-MMU-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Mus musculus 17816 R-PFA-1855174 https://reactome.org/PathwayBrowser/#/R-PFA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Plasmodium falciparum 17816 R-PFA-1855222 https://reactome.org/PathwayBrowser/#/R-PFA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Plasmodium falciparum 17816 R-RNO-1855174 https://reactome.org/PathwayBrowser/#/R-RNO-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Rattus norvegicus 17816 R-RNO-1855208 https://reactome.org/PathwayBrowser/#/R-RNO-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Rattus norvegicus 17816 R-RNO-1855222 https://reactome.org/PathwayBrowser/#/R-RNO-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Rattus norvegicus 17816 R-SCE-1855174 https://reactome.org/PathwayBrowser/#/R-SCE-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Saccharomyces cerevisiae 17816 R-SPO-1855174 https://reactome.org/PathwayBrowser/#/R-SPO-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Schizosaccharomyces pombe 17816 R-SPO-1855222 https://reactome.org/PathwayBrowser/#/R-SPO-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Schizosaccharomyces pombe 17816 R-SSC-1855174 https://reactome.org/PathwayBrowser/#/R-SSC-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Sus scrofa 17816 R-SSC-1855208 https://reactome.org/PathwayBrowser/#/R-SSC-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Sus scrofa 17816 R-SSC-1855222 https://reactome.org/PathwayBrowser/#/R-SSC-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Sus scrofa 17816 R-XTR-1855174 https://reactome.org/PathwayBrowser/#/R-XTR-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Xenopus tropicalis 17816 R-XTR-1855222 https://reactome.org/PathwayBrowser/#/R-XTR-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Xenopus tropicalis 17821 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17821 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 17821 R-BTA-110219 https://reactome.org/PathwayBrowser/#/R-BTA-110219 Cleavage of thymine by TDG glycosylase IEA Bos taurus 17821 R-BTA-110232 https://reactome.org/PathwayBrowser/#/R-BTA-110232 Cleavage of thymine by MBD4 glycosylase IEA Bos taurus 17821 R-BTA-73616 https://reactome.org/PathwayBrowser/#/R-BTA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Bos taurus 17821 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17821 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 17821 R-CEL-73616 https://reactome.org/PathwayBrowser/#/R-CEL-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Caenorhabditis elegans 17821 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17821 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 17821 R-CFA-110219 https://reactome.org/PathwayBrowser/#/R-CFA-110219 Cleavage of thymine by TDG glycosylase IEA Canis familiaris 17821 R-CFA-110232 https://reactome.org/PathwayBrowser/#/R-CFA-110232 Cleavage of thymine by MBD4 glycosylase IEA Canis familiaris 17821 R-CFA-73616 https://reactome.org/PathwayBrowser/#/R-CFA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Canis familiaris 17821 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17821 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 17821 R-DDI-73616 https://reactome.org/PathwayBrowser/#/R-DDI-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Dictyostelium discoideum 17821 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17821 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 17821 R-DME-110219 https://reactome.org/PathwayBrowser/#/R-DME-110219 Cleavage of thymine by TDG glycosylase IEA Drosophila melanogaster 17821 R-DME-73616 https://reactome.org/PathwayBrowser/#/R-DME-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Drosophila melanogaster 17821 R-DRE-110219 https://reactome.org/PathwayBrowser/#/R-DRE-110219 Cleavage of thymine by TDG glycosylase IEA Danio rerio 17821 R-DRE-73616 https://reactome.org/PathwayBrowser/#/R-DRE-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Danio rerio 17821 R-GGA-110219 https://reactome.org/PathwayBrowser/#/R-GGA-110219 Cleavage of thymine by TDG glycosylase IEA Gallus gallus 17821 R-GGA-110232 https://reactome.org/PathwayBrowser/#/R-GGA-110232 Cleavage of thymine by MBD4 glycosylase IEA Gallus gallus 17821 R-GGA-353277 https://reactome.org/PathwayBrowser/#/R-GGA-353277 Cleavage of thymine by 5-methylcytosine G/T mismatch specific glycosylase TAS Gallus gallus 17821 R-GGA-353444 https://reactome.org/PathwayBrowser/#/R-GGA-353444 Cleavage of thymine by TDG glycosylase TAS Gallus gallus 17821 R-GGA-73616 https://reactome.org/PathwayBrowser/#/R-GGA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Gallus gallus 17821 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17821 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 17821 R-HSA-110219 https://reactome.org/PathwayBrowser/#/R-HSA-110219 Cleavage of thymine by TDG glycosylase TAS Homo sapiens 17821 R-HSA-110232 https://reactome.org/PathwayBrowser/#/R-HSA-110232 Cleavage of thymine by MBD4 glycosylase TAS Homo sapiens 17821 R-HSA-112265 https://reactome.org/PathwayBrowser/#/R-HSA-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] TAS Homo sapiens 17821 R-HSA-112266 https://reactome.org/PathwayBrowser/#/R-HSA-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] TAS Homo sapiens 17821 R-HSA-73616 https://reactome.org/PathwayBrowser/#/R-HSA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ TAS Homo sapiens 17821 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17821 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 17821 R-MMU-110219 https://reactome.org/PathwayBrowser/#/R-MMU-110219 Cleavage of thymine by TDG glycosylase IEA Mus musculus 17821 R-MMU-110232 https://reactome.org/PathwayBrowser/#/R-MMU-110232 Cleavage of thymine by MBD4 glycosylase IEA Mus musculus 17821 R-MMU-112265 https://reactome.org/PathwayBrowser/#/R-MMU-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Mus musculus 17821 R-MMU-112266 https://reactome.org/PathwayBrowser/#/R-MMU-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Mus musculus 17821 R-MMU-73616 https://reactome.org/PathwayBrowser/#/R-MMU-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Mus musculus 17821 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17821 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 17821 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17821 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 17821 R-RNO-110219 https://reactome.org/PathwayBrowser/#/R-RNO-110219 Cleavage of thymine by TDG glycosylase IEA Rattus norvegicus 17821 R-RNO-110232 https://reactome.org/PathwayBrowser/#/R-RNO-110232 Cleavage of thymine by MBD4 glycosylase IEA Rattus norvegicus 17821 R-RNO-112265 https://reactome.org/PathwayBrowser/#/R-RNO-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Rattus norvegicus 17821 R-RNO-112266 https://reactome.org/PathwayBrowser/#/R-RNO-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Rattus norvegicus 17821 R-RNO-73616 https://reactome.org/PathwayBrowser/#/R-RNO-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Rattus norvegicus 17821 R-SPO-110219 https://reactome.org/PathwayBrowser/#/R-SPO-110219 Cleavage of thymine by TDG glycosylase IEA Schizosaccharomyces pombe 17821 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17821 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 17821 R-SSC-110219 https://reactome.org/PathwayBrowser/#/R-SSC-110219 Cleavage of thymine by TDG glycosylase IEA Sus scrofa 17821 R-SSC-110232 https://reactome.org/PathwayBrowser/#/R-SSC-110232 Cleavage of thymine by MBD4 glycosylase IEA Sus scrofa 17821 R-SSC-73616 https://reactome.org/PathwayBrowser/#/R-SSC-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Sus scrofa 17821 R-XTR-110219 https://reactome.org/PathwayBrowser/#/R-XTR-110219 Cleavage of thymine by TDG glycosylase IEA Xenopus tropicalis 17821 R-XTR-110232 https://reactome.org/PathwayBrowser/#/R-XTR-110232 Cleavage of thymine by MBD4 glycosylase IEA Xenopus tropicalis 17821 R-XTR-112265 https://reactome.org/PathwayBrowser/#/R-XTR-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Xenopus tropicalis 17821 R-XTR-112266 https://reactome.org/PathwayBrowser/#/R-XTR-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Xenopus tropicalis 17821 R-XTR-73616 https://reactome.org/PathwayBrowser/#/R-XTR-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Xenopus tropicalis 17823 R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 17823 R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 17823 R-BTA-211950 https://reactome.org/PathwayBrowser/#/R-BTA-211950 CYP24A1 24-hydroxylates CTL IEA Bos taurus 17823 R-BTA-8963915 https://reactome.org/PathwayBrowser/#/R-BTA-8963915 1,25(OH)2D binds VDR IEA Bos taurus 17823 R-CEL-8963915 https://reactome.org/PathwayBrowser/#/R-CEL-8963915 1,25(OH)2D binds VDR IEA Caenorhabditis elegans 17823 R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 17823 R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 17823 R-CFA-211950 https://reactome.org/PathwayBrowser/#/R-CFA-211950 CYP24A1 24-hydroxylates CTL IEA Canis familiaris 17823 R-CFA-8963915 https://reactome.org/PathwayBrowser/#/R-CFA-8963915 1,25(OH)2D binds VDR IEA Canis familiaris 17823 R-DME-8963915 https://reactome.org/PathwayBrowser/#/R-DME-8963915 1,25(OH)2D binds VDR IEA Drosophila melanogaster 17823 R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 17823 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 17823 R-DRE-211950 https://reactome.org/PathwayBrowser/#/R-DRE-211950 CYP24A1 24-hydroxylates CTL IEA Danio rerio 17823 R-DRE-8963915 https://reactome.org/PathwayBrowser/#/R-DRE-8963915 1,25(OH)2D binds VDR IEA Danio rerio 17823 R-GGA-8963915 https://reactome.org/PathwayBrowser/#/R-GGA-8963915 1,25(OH)2D binds VDR IEA Gallus gallus 17823 R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 17823 R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 17823 R-HSA-211950 https://reactome.org/PathwayBrowser/#/R-HSA-211950 CYP24A1 24-hydroxylates CTL TAS Homo sapiens 17823 R-HSA-5602004 https://reactome.org/PathwayBrowser/#/R-HSA-5602004 Defective CYP24A1 does not 24-hydroxylate CALTOL TAS Homo sapiens 17823 R-HSA-8963913 https://reactome.org/PathwayBrowser/#/R-HSA-8963913 1,25(OH)2D translocates from cytosol to nucleoplasm TAS Homo sapiens 17823 R-HSA-8963915 https://reactome.org/PathwayBrowser/#/R-HSA-8963915 1,25(OH)2D binds VDR TAS Homo sapiens 17823 R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 17823 R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 17823 R-MMU-211950 https://reactome.org/PathwayBrowser/#/R-MMU-211950 CYP24A1 24-hydroxylates CTL IEA Mus musculus 17823 R-MMU-8963915 https://reactome.org/PathwayBrowser/#/R-MMU-8963915 1,25(OH)2D binds VDR IEA Mus musculus 17823 R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 17823 R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 17823 R-RNO-211950 https://reactome.org/PathwayBrowser/#/R-RNO-211950 CYP24A1 24-hydroxylates CTL IEA Rattus norvegicus 17823 R-RNO-8963915 https://reactome.org/PathwayBrowser/#/R-RNO-8963915 1,25(OH)2D binds VDR IEA Rattus norvegicus 17823 R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 17823 R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 17823 R-SSC-211950 https://reactome.org/PathwayBrowser/#/R-SSC-211950 CYP24A1 24-hydroxylates CTL IEA Sus scrofa 17823 R-SSC-8963915 https://reactome.org/PathwayBrowser/#/R-SSC-8963915 1,25(OH)2D binds VDR IEA Sus scrofa 17823 R-XTR-8963915 https://reactome.org/PathwayBrowser/#/R-XTR-8963915 1,25(OH)2D binds VDR IEA Xenopus tropicalis 17825 R-BTA-429961 https://reactome.org/PathwayBrowser/#/R-BTA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Bos taurus 17825 R-BTA-5694126 https://reactome.org/PathwayBrowser/#/R-BTA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Bos taurus 17825 R-BTA-6814555 https://reactome.org/PathwayBrowser/#/R-BTA-6814555 Integrator complex processes the 3' end of snRNA IEA Bos taurus 17825 R-BTA-6814559 https://reactome.org/PathwayBrowser/#/R-BTA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Bos taurus 17825 R-BTA-6814885 https://reactome.org/PathwayBrowser/#/R-BTA-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Bos taurus 17825 R-CEL-429961 https://reactome.org/PathwayBrowser/#/R-CEL-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Caenorhabditis elegans 17825 R-CEL-5694126 https://reactome.org/PathwayBrowser/#/R-CEL-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Caenorhabditis elegans 17825 R-CEL-6814555 https://reactome.org/PathwayBrowser/#/R-CEL-6814555 Integrator complex processes the 3' end of snRNA IEA Caenorhabditis elegans 17825 R-CEL-6814559 https://reactome.org/PathwayBrowser/#/R-CEL-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Caenorhabditis elegans 17825 R-CEL-6814885 https://reactome.org/PathwayBrowser/#/R-CEL-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Caenorhabditis elegans 17825 R-CFA-429961 https://reactome.org/PathwayBrowser/#/R-CFA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Canis familiaris 17825 R-CFA-5694126 https://reactome.org/PathwayBrowser/#/R-CFA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Canis familiaris 17825 R-CFA-6814555 https://reactome.org/PathwayBrowser/#/R-CFA-6814555 Integrator complex processes the 3' end of snRNA IEA Canis familiaris 17825 R-CFA-6814559 https://reactome.org/PathwayBrowser/#/R-CFA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Canis familiaris 17825 R-CFA-6814885 https://reactome.org/PathwayBrowser/#/R-CFA-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Canis familiaris 17825 R-DDI-6814555 https://reactome.org/PathwayBrowser/#/R-DDI-6814555 Integrator complex processes the 3' end of snRNA IEA Dictyostelium discoideum 17825 R-DDI-6814559 https://reactome.org/PathwayBrowser/#/R-DDI-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Dictyostelium discoideum 17825 R-DME-429961 https://reactome.org/PathwayBrowser/#/R-DME-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Drosophila melanogaster 17825 R-DME-5694126 https://reactome.org/PathwayBrowser/#/R-DME-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Drosophila melanogaster 17825 R-DME-6814555 https://reactome.org/PathwayBrowser/#/R-DME-6814555 Integrator complex processes the 3' end of snRNA IEA Drosophila melanogaster 17825 R-DME-6814559 https://reactome.org/PathwayBrowser/#/R-DME-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Drosophila melanogaster 17825 R-DME-6814885 https://reactome.org/PathwayBrowser/#/R-DME-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Drosophila melanogaster 17825 R-DRE-6814555 https://reactome.org/PathwayBrowser/#/R-DRE-6814555 Integrator complex processes the 3' end of snRNA IEA Danio rerio 17825 R-DRE-6814559 https://reactome.org/PathwayBrowser/#/R-DRE-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Danio rerio 17825 R-GGA-429961 https://reactome.org/PathwayBrowser/#/R-GGA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Gallus gallus 17825 R-GGA-5694126 https://reactome.org/PathwayBrowser/#/R-GGA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Gallus gallus 17825 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus 17825 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus 17825 R-HSA-168280 https://reactome.org/PathwayBrowser/#/R-HSA-168280 Priming and Initiation of Transcription TAS Homo sapiens 17825 R-HSA-168301 https://reactome.org/PathwayBrowser/#/R-HSA-168301 Elongation, Polyadenylation and Termination TAS Homo sapiens 17825 R-HSA-191825 https://reactome.org/PathwayBrowser/#/R-HSA-191825 Nuclear export of snRNA transcripts TAS Homo sapiens 17825 R-HSA-429961 https://reactome.org/PathwayBrowser/#/R-HSA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA TAS Homo sapiens 17825 R-HSA-5694126 https://reactome.org/PathwayBrowser/#/R-HSA-5694126 NT5C3B hydrolyses 7MGP to 7MG TAS Homo sapiens 17825 R-HSA-6814555 https://reactome.org/PathwayBrowser/#/R-HSA-6814555 Integrator complex processes the 3' end of snRNA TAS Homo sapiens 17825 R-HSA-6814559 https://reactome.org/PathwayBrowser/#/R-HSA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine TAS Homo sapiens 17825 R-HSA-6814885 https://reactome.org/PathwayBrowser/#/R-HSA-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA TAS Homo sapiens 17825 R-MMU-429961 https://reactome.org/PathwayBrowser/#/R-MMU-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Mus musculus 17825 R-MMU-5694126 https://reactome.org/PathwayBrowser/#/R-MMU-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Mus musculus 17825 R-MMU-6814555 https://reactome.org/PathwayBrowser/#/R-MMU-6814555 Integrator complex processes the 3' end of snRNA IEA Mus musculus 17825 R-MMU-6814559 https://reactome.org/PathwayBrowser/#/R-MMU-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Mus musculus 17825 R-MMU-6814885 https://reactome.org/PathwayBrowser/#/R-MMU-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Mus musculus 17825 R-RNO-429961 https://reactome.org/PathwayBrowser/#/R-RNO-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Rattus norvegicus 17825 R-RNO-5694126 https://reactome.org/PathwayBrowser/#/R-RNO-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Rattus norvegicus 17825 R-RNO-6814555 https://reactome.org/PathwayBrowser/#/R-RNO-6814555 Integrator complex processes the 3' end of snRNA IEA Rattus norvegicus 17825 R-RNO-6814559 https://reactome.org/PathwayBrowser/#/R-RNO-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Rattus norvegicus 17825 R-RNO-6814885 https://reactome.org/PathwayBrowser/#/R-RNO-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Rattus norvegicus 17825 R-SCE-429961 https://reactome.org/PathwayBrowser/#/R-SCE-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Saccharomyces cerevisiae 17825 R-SPO-429961 https://reactome.org/PathwayBrowser/#/R-SPO-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Schizosaccharomyces pombe 17825 R-SSC-429961 https://reactome.org/PathwayBrowser/#/R-SSC-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Sus scrofa 17825 R-SSC-5694126 https://reactome.org/PathwayBrowser/#/R-SSC-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Sus scrofa 17825 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa 17825 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa 17825 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa 17825 R-XTR-429961 https://reactome.org/PathwayBrowser/#/R-XTR-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Xenopus tropicalis 17825 R-XTR-5694126 https://reactome.org/PathwayBrowser/#/R-XTR-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Xenopus tropicalis 17825 R-XTR-6814555 https://reactome.org/PathwayBrowser/#/R-XTR-6814555 Integrator complex processes the 3' end of snRNA IEA Xenopus tropicalis 17825 R-XTR-6814559 https://reactome.org/PathwayBrowser/#/R-XTR-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Xenopus tropicalis 17826 R-BTA-6800149 https://reactome.org/PathwayBrowser/#/R-BTA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Bos taurus 17826 R-CEL-6800149 https://reactome.org/PathwayBrowser/#/R-CEL-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Caenorhabditis elegans 17826 R-CFA-6800149 https://reactome.org/PathwayBrowser/#/R-CFA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Canis familiaris 17826 R-DDI-6800149 https://reactome.org/PathwayBrowser/#/R-DDI-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Dictyostelium discoideum 17826 R-DME-6800149 https://reactome.org/PathwayBrowser/#/R-DME-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Drosophila melanogaster 17826 R-DRE-6800149 https://reactome.org/PathwayBrowser/#/R-DRE-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Danio rerio 17826 R-HSA-6800149 https://reactome.org/PathwayBrowser/#/R-HSA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII TAS Homo sapiens 17826 R-MMU-6800149 https://reactome.org/PathwayBrowser/#/R-MMU-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Mus musculus 17826 R-PFA-6800149 https://reactome.org/PathwayBrowser/#/R-PFA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Plasmodium falciparum 17826 R-SCE-6800149 https://reactome.org/PathwayBrowser/#/R-SCE-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Saccharomyces cerevisiae 17826 R-SPO-6800149 https://reactome.org/PathwayBrowser/#/R-SPO-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Schizosaccharomyces pombe 17826 R-SSC-6800149 https://reactome.org/PathwayBrowser/#/R-SSC-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Sus scrofa 17826 R-XTR-6800149 https://reactome.org/PathwayBrowser/#/R-XTR-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Xenopus tropicalis 1784 R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 1784 R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 1784 R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 1784 R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 1784 R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 1784 R-RNO-76373 https://reactome.org/PathwayBrowser/#/R-RNO-76373 N-hydroxylation of 4-aminobiphenyl IEA Rattus norvegicus 1784 R-SSC-76373 https://reactome.org/PathwayBrowser/#/R-SSC-76373 N-hydroxylation of 4-aminobiphenyl IEA Sus scrofa 17843 R-HSA-141671 https://reactome.org/PathwayBrowser/#/R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex IEA Homo sapiens 17843 R-HSA-164500 https://reactome.org/PathwayBrowser/#/R-HSA-164500 Conformational changes in gp120 exposes gp41 TAS Homo sapiens 17843 R-HSA-164503 https://reactome.org/PathwayBrowser/#/R-HSA-164503 First strand transfer mediated by Repeated (R) sequence TAS Homo sapiens 17843 R-HSA-164504 https://reactome.org/PathwayBrowser/#/R-HSA-164504 Synthesis of minus strand strong stop DNA (-sssDNA) TAS Homo sapiens 17843 R-HSA-164507 https://reactome.org/PathwayBrowser/#/R-HSA-164507 CD4:gp120 binds to chemokine co-receptor CCR5/CXCR4 TAS Homo sapiens 17843 R-HSA-164508 https://reactome.org/PathwayBrowser/#/R-HSA-164508 N and C terminal heptad repeat helices of gp41 form six-helix bundle TAS Homo sapiens 17843 R-HSA-164509 https://reactome.org/PathwayBrowser/#/R-HSA-164509 Binding of gp120 of ENV oligomer to the host CD4 TAS Homo sapiens 17843 R-HSA-164510 https://reactome.org/PathwayBrowser/#/R-HSA-164510 Conformational change in gp120 of Env oligomer TAS Homo sapiens 17843 R-HSA-164512 https://reactome.org/PathwayBrowser/#/R-HSA-164512 Second strand transfer by annealing complementary PBS sequences TAS Homo sapiens 17843 R-HSA-164513 https://reactome.org/PathwayBrowser/#/R-HSA-164513 3' PPT-primed initiation of plus-strand DNA synthesis TAS Homo sapiens 17843 R-HSA-164515 https://reactome.org/PathwayBrowser/#/R-HSA-164515 Fusogenic activation of gp41 TAS Homo sapiens 17843 R-HSA-164519 https://reactome.org/PathwayBrowser/#/R-HSA-164519 RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex TAS Homo sapiens 17843 R-HSA-164520 https://reactome.org/PathwayBrowser/#/R-HSA-164520 Minus strand DNA synthesis resumes TAS Homo sapiens 17843 R-HSA-164521 https://reactome.org/PathwayBrowser/#/R-HSA-164521 Insertion of gp41 fusion peptide into the target membrane TAS Homo sapiens 17843 R-HSA-164524 https://reactome.org/PathwayBrowser/#/R-HSA-164524 Fusion of viral membrane with host cell membrane TAS Homo sapiens 17843 R-HSA-164527 https://reactome.org/PathwayBrowser/#/R-HSA-164527 Annealing of 3'-end of unwound transfer RNA primer with genomic RNA TAS Homo sapiens 17843 R-HSA-164528 https://reactome.org/PathwayBrowser/#/R-HSA-164528 RNase H-mediated cleavage of the template strand TAS Homo sapiens 17843 R-HSA-173111 https://reactome.org/PathwayBrowser/#/R-HSA-173111 Disassembly of viral capsid TAS Homo sapiens 17843 R-HSA-173642 https://reactome.org/PathwayBrowser/#/R-HSA-173642 Disintegration of matrix layer TAS Homo sapiens 17843 R-HSA-173769 https://reactome.org/PathwayBrowser/#/R-HSA-173769 RNase H-mediated digestion of tRNA, 3'PPT and cPPT RNA primers TAS Homo sapiens 17843 R-HSA-173771 https://reactome.org/PathwayBrowser/#/R-HSA-173771 Formation of RTC (Reverse Transcription Complex) TAS Homo sapiens 17843 R-HSA-180632 https://reactome.org/PathwayBrowser/#/R-HSA-180632 Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand TAS Homo sapiens 17843 R-HSA-180634 https://reactome.org/PathwayBrowser/#/R-HSA-180634 Association of APOBEC3G with single-stranded region of forming HIV-1 minus strand TAS Homo sapiens 17843 R-HSA-182795 https://reactome.org/PathwayBrowser/#/R-HSA-182795 RNase H-mediated degradation of the template strand TAS Homo sapiens 17843 R-HSA-182859 https://reactome.org/PathwayBrowser/#/R-HSA-182859 RNase H-mediated degradation of the RNA strand of the -sssDNA:RNA duplex TAS Homo sapiens 17843 R-HSA-3139027 https://reactome.org/PathwayBrowser/#/R-HSA-3139027 Maturation of HIV Virion TAS Homo sapiens 17843 R-HSA-3149454 https://reactome.org/PathwayBrowser/#/R-HSA-3149454 Packaging of HIV virion on the host cell plasma membrane TAS Homo sapiens 17843 R-HSA-3159227 https://reactome.org/PathwayBrowser/#/R-HSA-3159227 HIV Virion Budding TAS Homo sapiens 17843 R-HSA-5389839 https://reactome.org/PathwayBrowser/#/R-HSA-5389839 39S subunit binds 28S subunit:mRNA:fMet-tRNA IEA Homo sapiens 17843 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 17843 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 17843 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 17843 R-HSA-5419261 https://reactome.org/PathwayBrowser/#/R-HSA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP TAS Homo sapiens 17843 R-HSA-5419264 https://reactome.org/PathwayBrowser/#/R-HSA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA TAS Homo sapiens 17843 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 17843 R-HSA-5419273 https://reactome.org/PathwayBrowser/#/R-HSA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits TAS Homo sapiens 17843 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 17843 R-HSA-5419279 https://reactome.org/PathwayBrowser/#/R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) IEA Homo sapiens 17843 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 17843 R-HSA-5696807 https://reactome.org/PathwayBrowser/#/R-HSA-5696807 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 17843 R-HSA-5696813 https://reactome.org/PathwayBrowser/#/R-HSA-5696813 TSEN complex cleaves the intron from pre-tRNA TAS Homo sapiens 17843 R-HSA-5696816 https://reactome.org/PathwayBrowser/#/R-HSA-5696816 tRNA ligase complex ligates tRNA exons TAS Homo sapiens 17843 R-HSA-6782296 https://reactome.org/PathwayBrowser/#/R-HSA-6782296 DUS2:EPRS reduces uridine to dihydrouridine in tRNAs IEA Homo sapiens 17843 R-HSA-6783483 https://reactome.org/PathwayBrowser/#/R-HSA-6783483 tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol TAS Homo sapiens 17843 R-HSA-6784462 https://reactome.org/PathwayBrowser/#/R-HSA-6784462 TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs IEA Homo sapiens 17843 R-HSA-6784494 https://reactome.org/PathwayBrowser/#/R-HSA-6784494 EKC complex threonylcarbamoylates A37 of tRNAs IEA Homo sapiens 17843 R-HSA-6785478 https://reactome.org/PathwayBrowser/#/R-HSA-6785478 Processed tRNA binds XPOT and RAN:GTP TAS Homo sapiens 17843 R-HSA-6786501 https://reactome.org/PathwayBrowser/#/R-HSA-6786501 TRMT11:TRMT112 methylates guanosine-10 in tRNA IEA Homo sapiens 17843 R-HSA-6786567 https://reactome.org/PathwayBrowser/#/R-HSA-6786567 KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine TAS Homo sapiens 17843 R-HSA-6786571 https://reactome.org/PathwayBrowser/#/R-HSA-6786571 CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37 TAS Homo sapiens 17843 R-HSA-6786583 https://reactome.org/PathwayBrowser/#/R-HSA-6786583 PUS7 transforms uridine to pseudouridine in tRNAs IEA Homo sapiens 17843 R-HSA-6786621 https://reactome.org/PathwayBrowser/#/R-HSA-6786621 TRMT10A methylates guanosine-9 in tRNA IEA Homo sapiens 17843 R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 17843 R-HSA-6787525 https://reactome.org/PathwayBrowser/#/R-HSA-6787525 TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58 TAS Homo sapiens 17843 R-HSA-6787567 https://reactome.org/PathwayBrowser/#/R-HSA-6787567 TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) TAS Homo sapiens 17843 R-HSA-6787591 https://reactome.org/PathwayBrowser/#/R-HSA-6787591 TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9 TAS Homo sapiens 17843 R-HSA-6787594 https://reactome.org/PathwayBrowser/#/R-HSA-6787594 TRMT10C:HSD17B10 (TRMT10C:SDR5C1) methylates adenosine-9 in tRNA yielding 1-methyladenosine-9 TAS Homo sapiens 17843 R-HSA-8870289 https://reactome.org/PathwayBrowser/#/R-HSA-8870289 PUS3 transforms uridine-39 to pseudouridine-39 in tRNA TAS Homo sapiens 17843 R-HSA-9014610 https://reactome.org/PathwayBrowser/#/R-HSA-9014610 Translation of ROBO3.2 mRNA initiates NMD IEA Homo sapiens 17843 R-HSA-9014652 https://reactome.org/PathwayBrowser/#/R-HSA-9014652 Translation of ROBO3.2 mRNA is negatively regulated by NMD IEA Homo sapiens 17843 R-HSA-927789 https://reactome.org/PathwayBrowser/#/R-HSA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex TAS Homo sapiens 17843 R-HSA-927813 https://reactome.org/PathwayBrowser/#/R-HSA-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A TAS Homo sapiens 17843 R-HSA-927832 https://reactome.org/PathwayBrowser/#/R-HSA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex TAS Homo sapiens 17843 R-HSA-927836 https://reactome.org/PathwayBrowser/#/R-HSA-927836 SMG6 hydrolyzes mRNA with premature termination codon TAS Homo sapiens 17843 R-HSA-927889 https://reactome.org/PathwayBrowser/#/R-HSA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) TAS Homo sapiens 17843 R-HSA-9633005 https://reactome.org/PathwayBrowser/#/R-HSA-9633005 EIF2AK4 (GCN2) binds tRNA IEA Homo sapiens 17843 R-HSA-9633008 https://reactome.org/PathwayBrowser/#/R-HSA-9633008 p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1 IEA Homo sapiens 17843 R-HSA-9633742 https://reactome.org/PathwayBrowser/#/R-HSA-9633742 EIF2AK4 (GCN2) dimer autophosphorylates IEA Homo sapiens 17843 R-HSA-9697051 https://reactome.org/PathwayBrowser/#/R-HSA-9697051 RTC binds NRTIs TAS Homo sapiens 17843 R-HSA-9708408 https://reactome.org/PathwayBrowser/#/R-HSA-9708408 DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid TAS Homo sapiens 17843 R-MMU-9633481 https://reactome.org/PathwayBrowser/#/R-MMU-9633481 Eif2ak4 binds tRNA IEA Mus musculus 17843 R-MMU-9633504 https://reactome.org/PathwayBrowser/#/R-MMU-9633504 Eif2ak4 phosphorylates Eif2s1 IEA Mus musculus 17843 R-MMU-9633741 https://reactome.org/PathwayBrowser/#/R-MMU-9633741 Eif2ak4 dimer autophosphorylates IEA Mus musculus 17843 R-SCE-141698 https://reactome.org/PathwayBrowser/#/R-SCE-141698 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex TAS Saccharomyces cerevisiae 17843 R-SCE-6784469 https://reactome.org/PathwayBrowser/#/R-SCE-6784469 EKC/KEOPS complex threonylcarbamoylates adenosine-37 of tRNAs TAS Saccharomyces cerevisiae 17843 R-SCE-6786492 https://reactome.org/PathwayBrowser/#/R-SCE-6786492 TRM11:TRM112 methylates guanosine-10 in tRNA yielding N(2)-methylguanosine-10 TAS Saccharomyces cerevisiae 17843 R-SCE-6786558 https://reactome.org/PathwayBrowser/#/R-SCE-6786558 PUS7 transforms uridine to pseudouridine at nucleotide 13 of tRNA TAS Saccharomyces cerevisiae 17843 R-SCE-6786632 https://reactome.org/PathwayBrowser/#/R-SCE-6786632 TRM10 methylates guanosine-9 in tRNA TAS Saccharomyces cerevisiae 17843 R-SCE-6790167 https://reactome.org/PathwayBrowser/#/R-SCE-6790167 MOD5 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) TAS Saccharomyces cerevisiae 17843 R-SCE-9633467 https://reactome.org/PathwayBrowser/#/R-SCE-9633467 GCN2 binds tRNA TAS Saccharomyces cerevisiae 17843 R-SCE-9633480 https://reactome.org/PathwayBrowser/#/R-SCE-9633480 GCN2 phosphorylates SUI2 TAS Saccharomyces cerevisiae 17843 R-SCE-9633750 https://reactome.org/PathwayBrowser/#/R-SCE-9633750 GCN2 dimer autophosphorylates TAS Saccharomyces cerevisiae 17851 R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 17851 R-HSA-9681314 https://reactome.org/PathwayBrowser/#/R-HSA-9681314 Replication transcription complex binds SARS-CoV-1 genomic RNA TAS Homo sapiens 17851 R-HSA-9681651 https://reactome.org/PathwayBrowser/#/R-HSA-9681651 nsp8 generates RNA primers TAS Homo sapiens 17851 R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 17851 R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 17851 R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 17851 R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 17851 R-HSA-9682603 https://reactome.org/PathwayBrowser/#/R-HSA-9682603 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 17851 R-HSA-9682695 https://reactome.org/PathwayBrowser/#/R-HSA-9682695 nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template TAS Homo sapiens 17851 R-HSA-9683618 https://reactome.org/PathwayBrowser/#/R-HSA-9683618 mRNA3 is translated to protein 3a TAS Homo sapiens 17851 R-HSA-9683622 https://reactome.org/PathwayBrowser/#/R-HSA-9683622 mRNA5 is translated to protein M TAS Homo sapiens 17851 R-HSA-9683624 https://reactome.org/PathwayBrowser/#/R-HSA-9683624 mRNA2 is translated to Spike TAS Homo sapiens 17851 R-HSA-9683656 https://reactome.org/PathwayBrowser/#/R-HSA-9683656 mRNA4 is translated to protein E TAS Homo sapiens 17851 R-HSA-9683735 https://reactome.org/PathwayBrowser/#/R-HSA-9683735 mRNA9 is translated to Nucleoprotein TAS Homo sapiens 17851 R-HSA-9684030 https://reactome.org/PathwayBrowser/#/R-HSA-9684030 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 17851 R-HSA-9684032 https://reactome.org/PathwayBrowser/#/R-HSA-9684032 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 17851 R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 17851 R-HSA-9684229 https://reactome.org/PathwayBrowser/#/R-HSA-9684229 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 17851 R-HSA-9684234 https://reactome.org/PathwayBrowser/#/R-HSA-9684234 Encapsidation of SARS coronavirus genomic RNA TAS Homo sapiens 17851 R-HSA-9684238 https://reactome.org/PathwayBrowser/#/R-HSA-9684238 E and N are recruited to the M lattice TAS Homo sapiens 17851 R-HSA-9684241 https://reactome.org/PathwayBrowser/#/R-HSA-9684241 Recruitment of Spike trimer to assembling virion TAS Homo sapiens 17851 R-HSA-9684277 https://reactome.org/PathwayBrowser/#/R-HSA-9684277 mRNA1 is translated to pp1ab TAS Homo sapiens 17851 R-HSA-9684301 https://reactome.org/PathwayBrowser/#/R-HSA-9684301 mRNA1 is translated to pp1a TAS Homo sapiens 17851 R-HSA-9685519 https://reactome.org/PathwayBrowser/#/R-HSA-9685519 Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) TAS Homo sapiens 17851 R-HSA-9685531 https://reactome.org/PathwayBrowser/#/R-HSA-9685531 SARS virus buds into ERGIC lumen TAS Homo sapiens 17851 R-HSA-9685597 https://reactome.org/PathwayBrowser/#/R-HSA-9685597 RTC binds SARS-CoV-1 genomic RNA complement (minus strand) TAS Homo sapiens 17851 R-HSA-9685639 https://reactome.org/PathwayBrowser/#/R-HSA-9685639 Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching TAS Homo sapiens 17851 R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 17851 R-HSA-9686174 https://reactome.org/PathwayBrowser/#/R-HSA-9686174 Accessory proteins are recruited to the maturing virion TAS Homo sapiens 17851 R-HSA-9687384 https://reactome.org/PathwayBrowser/#/R-HSA-9687384 SARS-CoV-1 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 17851 R-HSA-9687388 https://reactome.org/PathwayBrowser/#/R-HSA-9687388 SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 17851 R-HSA-9693589 https://reactome.org/PathwayBrowser/#/R-HSA-9693589 SARS-CoV-1 dsRNA intermediates bind DDX58 TAS Homo sapiens 17851 R-HSA-9693590 https://reactome.org/PathwayBrowser/#/R-HSA-9693590 SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC IEA Homo sapiens 17851 R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 17851 R-HSA-9694274 https://reactome.org/PathwayBrowser/#/R-HSA-9694274 mRNA1 is translated to pp1ab IEA Homo sapiens 17851 R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 17851 R-HSA-9694280 https://reactome.org/PathwayBrowser/#/R-HSA-9694280 mRNA4 is translated to protein E TAS Homo sapiens 17851 R-HSA-9694281 https://reactome.org/PathwayBrowser/#/R-HSA-9694281 Encapsidation of SARS coronavirus genomic RNA IEA Homo sapiens 17851 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 17851 R-HSA-9694334 https://reactome.org/PathwayBrowser/#/R-HSA-9694334 mRNA1 is translated to pp1a IEA Homo sapiens 17851 R-HSA-9694344 https://reactome.org/PathwayBrowser/#/R-HSA-9694344 Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching IEA Homo sapiens 17851 R-HSA-9694370 https://reactome.org/PathwayBrowser/#/R-HSA-9694370 mRNA9a is translated to Nucleoprotein TAS Homo sapiens 17851 R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 17851 R-HSA-9694444 https://reactome.org/PathwayBrowser/#/R-HSA-9694444 E and N are recruited to the M lattice IEA Homo sapiens 17851 R-HSA-9694447 https://reactome.org/PathwayBrowser/#/R-HSA-9694447 mRNA2 is translated to Spike TAS Homo sapiens 17851 R-HSA-9694454 https://reactome.org/PathwayBrowser/#/R-HSA-9694454 Replication transcription complex binds SARS-CoV-2 genomic RNA TAS Homo sapiens 17851 R-HSA-9694455 https://reactome.org/PathwayBrowser/#/R-HSA-9694455 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 17851 R-HSA-9694471 https://reactome.org/PathwayBrowser/#/R-HSA-9694471 Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) TAS Homo sapiens 17851 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 17851 R-HSA-9694495 https://reactome.org/PathwayBrowser/#/R-HSA-9694495 RTC binds SARS-CoV-2 genomic RNA complement (minus strand) IEA Homo sapiens 17851 R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 17851 R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 17851 R-HSA-9694528 https://reactome.org/PathwayBrowser/#/R-HSA-9694528 Accessory proteins are recruited to the maturing virion IEA Homo sapiens 17851 R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 17851 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 17851 R-HSA-9694553 https://reactome.org/PathwayBrowser/#/R-HSA-9694553 Recruitment of Spike trimer to assembling virion IEA Homo sapiens 17851 R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 17851 R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 17851 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 17851 R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 17851 R-HSA-9694633 https://reactome.org/PathwayBrowser/#/R-HSA-9694633 SARS virus buds into ERGIC lumen IEA Homo sapiens 17851 R-HSA-9694641 https://reactome.org/PathwayBrowser/#/R-HSA-9694641 Viral release IEA Homo sapiens 17851 R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 17851 R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 17851 R-HSA-9694677 https://reactome.org/PathwayBrowser/#/R-HSA-9694677 ZCRB1 binds 5'UTR of SARS-CoV-2 genomic RNA IEA Homo sapiens 17851 R-HSA-9694681 https://reactome.org/PathwayBrowser/#/R-HSA-9694681 mRNA5 is translated to protein M TAS Homo sapiens 17851 R-HSA-9694689 https://reactome.org/PathwayBrowser/#/R-HSA-9694689 Fusion and Release of SARS-CoV-2 Nucleocapsid IEA Homo sapiens 17851 R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 17851 R-HSA-9694723 https://reactome.org/PathwayBrowser/#/R-HSA-9694723 Uncoating of SARS-CoV-2 Genome IEA Homo sapiens 17851 R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 17851 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 17851 R-HSA-9694794 https://reactome.org/PathwayBrowser/#/R-HSA-9694794 mRNA3 is translated to protein 3a TAS Homo sapiens 17851 R-HSA-9697423 https://reactome.org/PathwayBrowser/#/R-HSA-9697423 Endocytosis of SARS-CoV-2 Virion IEA Homo sapiens 17851 R-HSA-9698988 https://reactome.org/PathwayBrowser/#/R-HSA-9698988 Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid TAS Homo sapiens 17851 R-HSA-9699007 https://reactome.org/PathwayBrowser/#/R-HSA-9699007 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 17851 R-HSA-9705961 https://reactome.org/PathwayBrowser/#/R-HSA-9705961 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 17851 R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 17851 R-HSA-9727292 https://reactome.org/PathwayBrowser/#/R-HSA-9727292 mRNA6 is translated to protein 6 TAS Homo sapiens 17851 R-HSA-9727297 https://reactome.org/PathwayBrowser/#/R-HSA-9727297 mRNA7 is translated to protein 7a TAS Homo sapiens 17851 R-HSA-9727303 https://reactome.org/PathwayBrowser/#/R-HSA-9727303 mRNA9 is translated to protein 9b TAS Homo sapiens 17851 R-HSA-9727305 https://reactome.org/PathwayBrowser/#/R-HSA-9727305 mRNA8 is translated to protein 8 TAS Homo sapiens 17851 R-HSA-9754745 https://reactome.org/PathwayBrowser/#/R-HSA-9754745 IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 17851 R-HSA-9755252 https://reactome.org/PathwayBrowser/#/R-HSA-9755252 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 17851 R-HSA-9755258 https://reactome.org/PathwayBrowser/#/R-HSA-9755258 DDX58 binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 17851 R-HSA-9755368 https://reactome.org/PathwayBrowser/#/R-HSA-9755368 TLR2:TLR1 binds SARS-CoV-2 E pentamer TAS Homo sapiens 17851 R-HSA-9756574 https://reactome.org/PathwayBrowser/#/R-HSA-9756574 SARS-CoV-2 S binds SFTPD 12mer TAS Homo sapiens 17851 R-HSA-9759709 https://reactome.org/PathwayBrowser/#/R-HSA-9759709 CNBP binds SARS-CoV-2 G-rich RNA TAS Homo sapiens 17851 R-HSA-9760510 https://reactome.org/PathwayBrowser/#/R-HSA-9760510 LARP1 binds SARS-CoV-2 RNA TAS Homo sapiens 17851 R-HSA-9769949 https://reactome.org/PathwayBrowser/#/R-HSA-9769949 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage TAS Homo sapiens 17851 R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 17855 R-BTA-1482647 https://reactome.org/PathwayBrowser/#/R-BTA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Bos taurus 17855 R-BTA-1482777 https://reactome.org/PathwayBrowser/#/R-BTA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Bos taurus 17855 R-BTA-1482889 https://reactome.org/PathwayBrowser/#/R-BTA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Bos taurus 17855 R-BTA-171059 https://reactome.org/PathwayBrowser/#/R-BTA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Bos taurus 17855 R-BTA-171106 https://reactome.org/PathwayBrowser/#/R-BTA-171106 LDLR:LDL complex => LDLR + LDL IEA Bos taurus 17855 R-BTA-171122 https://reactome.org/PathwayBrowser/#/R-BTA-171122 LDL + LDLR => LDL:LDLR complex IEA Bos taurus 17855 R-BTA-171141 https://reactome.org/PathwayBrowser/#/R-BTA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Bos taurus 17855 R-BTA-174587 https://reactome.org/PathwayBrowser/#/R-BTA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Bos taurus 17855 R-BTA-174657 https://reactome.org/PathwayBrowser/#/R-BTA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Bos taurus 17855 R-BTA-174660 https://reactome.org/PathwayBrowser/#/R-BTA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Bos taurus 17855 R-BTA-174690 https://reactome.org/PathwayBrowser/#/R-BTA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Bos taurus 17855 R-BTA-174706 https://reactome.org/PathwayBrowser/#/R-BTA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Bos taurus 17855 R-BTA-174739 https://reactome.org/PathwayBrowser/#/R-BTA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Bos taurus 17855 R-BTA-174741 https://reactome.org/PathwayBrowser/#/R-BTA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Bos taurus 17855 R-BTA-174757 https://reactome.org/PathwayBrowser/#/R-BTA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Bos taurus 17855 R-BTA-174786 https://reactome.org/PathwayBrowser/#/R-BTA-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Bos taurus 17855 R-BTA-192422 https://reactome.org/PathwayBrowser/#/R-BTA-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Bos taurus 17855 R-BTA-192430 https://reactome.org/PathwayBrowser/#/R-BTA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 17855 R-BTA-192475 https://reactome.org/PathwayBrowser/#/R-BTA-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Bos taurus 17855 R-BTA-203130 https://reactome.org/PathwayBrowser/#/R-BTA-203130 OLR1 binds to oxidized LDL IEA Bos taurus 17855 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 17855 R-BTA-2187332 https://reactome.org/PathwayBrowser/#/R-BTA-2187332 Cytosolic CMs translocate to extracellular region IEA Bos taurus 17855 R-BTA-2197646 https://reactome.org/PathwayBrowser/#/R-BTA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Bos taurus 17855 R-BTA-2197770 https://reactome.org/PathwayBrowser/#/R-BTA-2197770 STAB1 (FEEL-1) binds ligands IEA Bos taurus 17855 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 17855 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 17855 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 17855 R-BTA-2247513 https://reactome.org/PathwayBrowser/#/R-BTA-2247513 STAB1:ligand is endocytosed IEA Bos taurus 17855 R-BTA-2395764 https://reactome.org/PathwayBrowser/#/R-BTA-2395764 atREs binds to nascent CM IEA Bos taurus 17855 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 17855 R-BTA-2395784 https://reactome.org/PathwayBrowser/#/R-BTA-2395784 Nascent CMs transform into mature CMs IEA Bos taurus 17855 R-BTA-2404131 https://reactome.org/PathwayBrowser/#/R-BTA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Bos taurus 17855 R-BTA-2423785 https://reactome.org/PathwayBrowser/#/R-BTA-2423785 CR:atREs binds apoE and HSPG IEA Bos taurus 17855 R-BTA-2512800 https://reactome.org/PathwayBrowser/#/R-BTA-2512800 SCARB1:ligand is endocytosed IEA Bos taurus 17855 R-BTA-266299 https://reactome.org/PathwayBrowser/#/R-BTA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Bos taurus 17855 R-BTA-266303 https://reactome.org/PathwayBrowser/#/R-BTA-266303 Spherical HDL binds C and E apolipoproteins IEA Bos taurus 17855 R-BTA-266310 https://reactome.org/PathwayBrowser/#/R-BTA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Bos taurus 17855 R-BTA-266315 https://reactome.org/PathwayBrowser/#/R-BTA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Bos taurus 17855 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 17855 R-BTA-349637 https://reactome.org/PathwayBrowser/#/R-BTA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Bos taurus 17855 R-BTA-349638 https://reactome.org/PathwayBrowser/#/R-BTA-349638 Disassembly of SR-BI-bound spherical HDL IEA Bos taurus 17855 R-BTA-432121 https://reactome.org/PathwayBrowser/#/R-BTA-432121 LDL binds to LRP8 IEA Bos taurus 17855 R-BTA-432129 https://reactome.org/PathwayBrowser/#/R-BTA-432129 FGR binds and phosphorylates LRP8 IEA Bos taurus 17855 R-BTA-435244 https://reactome.org/PathwayBrowser/#/R-BTA-435244 PECAM1 is phosphorylated IEA Bos taurus 17855 R-BTA-5694109 https://reactome.org/PathwayBrowser/#/R-BTA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Bos taurus 17855 R-BTA-6789310 https://reactome.org/PathwayBrowser/#/R-BTA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Bos taurus 17855 R-BTA-75900 https://reactome.org/PathwayBrowser/#/R-BTA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Bos taurus 17855 R-BTA-8848338 https://reactome.org/PathwayBrowser/#/R-BTA-8848338 PNPLA4 hydrolyzes TAG IEA Bos taurus 17855 R-BTA-8848580 https://reactome.org/PathwayBrowser/#/R-BTA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Bos taurus 17855 R-BTA-8856630 https://reactome.org/PathwayBrowser/#/R-BTA-8856630 CIDEA:CIDEC binds lipid droplets IEA Bos taurus 17855 R-BTA-8857686 https://reactome.org/PathwayBrowser/#/R-BTA-8857686 FITM1, FITM2 bind TAGs IEA Bos taurus 17855 R-BTA-8858252 https://reactome.org/PathwayBrowser/#/R-BTA-8858252 HDLBP binds HDL IEA Bos taurus 17855 R-BTA-8862380 https://reactome.org/PathwayBrowser/#/R-BTA-8862380 HSD17B13 binds lipid droplets IEA Bos taurus 17855 R-BTA-8863471 https://reactome.org/PathwayBrowser/#/R-BTA-8863471 LDLR is bound by DAB2 and ARH IEA Bos taurus 17855 R-BTA-8865667 https://reactome.org/PathwayBrowser/#/R-BTA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Bos taurus 17855 R-BTA-8866304 https://reactome.org/PathwayBrowser/#/R-BTA-8866304 pre-VLDL binds lipids to form VLDL IEA Bos taurus 17855 R-BTA-8866308 https://reactome.org/PathwayBrowser/#/R-BTA-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Bos taurus 17855 R-BTA-8866327 https://reactome.org/PathwayBrowser/#/R-BTA-8866327 VLDL translocates from SER lumen to extracellular region IEA Bos taurus 17855 R-BTA-8866329 https://reactome.org/PathwayBrowser/#/R-BTA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Bos taurus 17855 R-BTA-8867754 https://reactome.org/PathwayBrowser/#/R-BTA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Bos taurus 17855 R-BTA-8867756 https://reactome.org/PathwayBrowser/#/R-BTA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Bos taurus 17855 R-BTA-8868071 https://reactome.org/PathwayBrowser/#/R-BTA-8868071 Clathrin recruits PIK3C2A IEA Bos taurus 17855 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 17855 R-BTA-8868230 https://reactome.org/PathwayBrowser/#/R-BTA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Bos taurus 17855 R-BTA-8868236 https://reactome.org/PathwayBrowser/#/R-BTA-8868236 BAR domain proteins recruit dynamin IEA Bos taurus 17855 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 17855 R-BTA-8868651 https://reactome.org/PathwayBrowser/#/R-BTA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Bos taurus 17855 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 17855 R-BTA-8868659 https://reactome.org/PathwayBrowser/#/R-BTA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Bos taurus 17855 R-BTA-8868660 https://reactome.org/PathwayBrowser/#/R-BTA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Bos taurus 17855 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 17855 R-BTA-8869667 https://reactome.org/PathwayBrowser/#/R-BTA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Bos taurus 17855 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 17855 R-BTA-8871194 https://reactome.org/PathwayBrowser/#/R-BTA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Bos taurus 17855 R-BTA-8876366 https://reactome.org/PathwayBrowser/#/R-BTA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Bos taurus 17855 R-BTA-8948034 https://reactome.org/PathwayBrowser/#/R-BTA-8948034 FGR binds LDL:LRP8 IEA Bos taurus 17855 R-BTA-8979996 https://reactome.org/PathwayBrowser/#/R-BTA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Bos taurus 17855 R-BTA-8980228 https://reactome.org/PathwayBrowser/#/R-BTA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Bos taurus 17855 R-BTA-9707586 https://reactome.org/PathwayBrowser/#/R-BTA-9707586 FeHM oxidises LDL,HDL IEA Bos taurus 17855 R-BTA-9737780 https://reactome.org/PathwayBrowser/#/R-BTA-9737780 MTTP binds lomitapide IEA Bos taurus 17855 R-CEL-1482647 https://reactome.org/PathwayBrowser/#/R-CEL-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Caenorhabditis elegans 17855 R-CEL-1482777 https://reactome.org/PathwayBrowser/#/R-CEL-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Caenorhabditis elegans 17855 R-CEL-1482889 https://reactome.org/PathwayBrowser/#/R-CEL-1482889 DAG is acylated to TAG by DGAT1/2 IEA Caenorhabditis elegans 17855 R-CEL-192430 https://reactome.org/PathwayBrowser/#/R-CEL-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 17855 R-CEL-549192 https://reactome.org/PathwayBrowser/#/R-CEL-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Caenorhabditis elegans 17855 R-CEL-75900 https://reactome.org/PathwayBrowser/#/R-CEL-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Caenorhabditis elegans 17855 R-CEL-8848339 https://reactome.org/PathwayBrowser/#/R-CEL-8848339 PNPLA5 hydrolyzes TAG IEA Caenorhabditis elegans 17855 R-CEL-8848580 https://reactome.org/PathwayBrowser/#/R-CEL-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Caenorhabditis elegans 17855 R-CEL-8857686 https://reactome.org/PathwayBrowser/#/R-CEL-8857686 FITM1, FITM2 bind TAGs IEA Caenorhabditis elegans 17855 R-CEL-9737780 https://reactome.org/PathwayBrowser/#/R-CEL-9737780 MTTP binds lomitapide IEA Caenorhabditis elegans 17855 R-CFA-1482647 https://reactome.org/PathwayBrowser/#/R-CFA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Canis familiaris 17855 R-CFA-1482777 https://reactome.org/PathwayBrowser/#/R-CFA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Canis familiaris 17855 R-CFA-1482889 https://reactome.org/PathwayBrowser/#/R-CFA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Canis familiaris 17855 R-CFA-171059 https://reactome.org/PathwayBrowser/#/R-CFA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Canis familiaris 17855 R-CFA-171106 https://reactome.org/PathwayBrowser/#/R-CFA-171106 LDLR:LDL complex => LDLR + LDL IEA Canis familiaris 17855 R-CFA-171122 https://reactome.org/PathwayBrowser/#/R-CFA-171122 LDL + LDLR => LDL:LDLR complex IEA Canis familiaris 17855 R-CFA-171141 https://reactome.org/PathwayBrowser/#/R-CFA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Canis familiaris 17855 R-CFA-174587 https://reactome.org/PathwayBrowser/#/R-CFA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Canis familiaris 17855 R-CFA-174657 https://reactome.org/PathwayBrowser/#/R-CFA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Canis familiaris 17855 R-CFA-174660 https://reactome.org/PathwayBrowser/#/R-CFA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Canis familiaris 17855 R-CFA-174690 https://reactome.org/PathwayBrowser/#/R-CFA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Canis familiaris 17855 R-CFA-174706 https://reactome.org/PathwayBrowser/#/R-CFA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Canis familiaris 17855 R-CFA-174739 https://reactome.org/PathwayBrowser/#/R-CFA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Canis familiaris 17855 R-CFA-174741 https://reactome.org/PathwayBrowser/#/R-CFA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Canis familiaris 17855 R-CFA-174757 https://reactome.org/PathwayBrowser/#/R-CFA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Canis familiaris 17855 R-CFA-174786 https://reactome.org/PathwayBrowser/#/R-CFA-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Canis familiaris 17855 R-CFA-203130 https://reactome.org/PathwayBrowser/#/R-CFA-203130 OLR1 binds to oxidized LDL IEA Canis familiaris 17855 R-CFA-2187332 https://reactome.org/PathwayBrowser/#/R-CFA-2187332 Cytosolic CMs translocate to extracellular region IEA Canis familiaris 17855 R-CFA-2197646 https://reactome.org/PathwayBrowser/#/R-CFA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Canis familiaris 17855 R-CFA-2197770 https://reactome.org/PathwayBrowser/#/R-CFA-2197770 STAB1 (FEEL-1) binds ligands IEA Canis familiaris 17855 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 17855 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 17855 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 17855 R-CFA-2247513 https://reactome.org/PathwayBrowser/#/R-CFA-2247513 STAB1:ligand is endocytosed IEA Canis familiaris 17855 R-CFA-2395764 https://reactome.org/PathwayBrowser/#/R-CFA-2395764 atREs binds to nascent CM IEA Canis familiaris 17855 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 17855 R-CFA-2395784 https://reactome.org/PathwayBrowser/#/R-CFA-2395784 Nascent CMs transform into mature CMs IEA Canis familiaris 17855 R-CFA-2404131 https://reactome.org/PathwayBrowser/#/R-CFA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Canis familiaris 17855 R-CFA-2423785 https://reactome.org/PathwayBrowser/#/R-CFA-2423785 CR:atREs binds apoE and HSPG IEA Canis familiaris 17855 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 17855 R-CFA-2512800 https://reactome.org/PathwayBrowser/#/R-CFA-2512800 SCARB1:ligand is endocytosed IEA Canis familiaris 17855 R-CFA-266299 https://reactome.org/PathwayBrowser/#/R-CFA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Canis familiaris 17855 R-CFA-266303 https://reactome.org/PathwayBrowser/#/R-CFA-266303 Spherical HDL binds C and E apolipoproteins IEA Canis familiaris 17855 R-CFA-349637 https://reactome.org/PathwayBrowser/#/R-CFA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Canis familiaris 17855 R-CFA-349638 https://reactome.org/PathwayBrowser/#/R-CFA-349638 Disassembly of SR-BI-bound spherical HDL IEA Canis familiaris 17855 R-CFA-432121 https://reactome.org/PathwayBrowser/#/R-CFA-432121 LDL binds to LRP8 IEA Canis familiaris 17855 R-CFA-432129 https://reactome.org/PathwayBrowser/#/R-CFA-432129 FGR binds and phosphorylates LRP8 IEA Canis familiaris 17855 R-CFA-435244 https://reactome.org/PathwayBrowser/#/R-CFA-435244 PECAM1 is phosphorylated IEA Canis familiaris 17855 R-CFA-549192 https://reactome.org/PathwayBrowser/#/R-CFA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Canis familiaris 17855 R-CFA-5694109 https://reactome.org/PathwayBrowser/#/R-CFA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Canis familiaris 17855 R-CFA-6789310 https://reactome.org/PathwayBrowser/#/R-CFA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Canis familiaris 17855 R-CFA-75900 https://reactome.org/PathwayBrowser/#/R-CFA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Canis familiaris 17855 R-CFA-8848338 https://reactome.org/PathwayBrowser/#/R-CFA-8848338 PNPLA4 hydrolyzes TAG IEA Canis familiaris 17855 R-CFA-8848339 https://reactome.org/PathwayBrowser/#/R-CFA-8848339 PNPLA5 hydrolyzes TAG IEA Canis familiaris 17855 R-CFA-8854408 https://reactome.org/PathwayBrowser/#/R-CFA-8854408 APOBR dimer binds VLDLs IEA Canis familiaris 17855 R-CFA-8854462 https://reactome.org/PathwayBrowser/#/R-CFA-8854462 VLDLR binds VLDL IEA Canis familiaris 17855 R-CFA-8856630 https://reactome.org/PathwayBrowser/#/R-CFA-8856630 CIDEA:CIDEC binds lipid droplets IEA Canis familiaris 17855 R-CFA-8857686 https://reactome.org/PathwayBrowser/#/R-CFA-8857686 FITM1, FITM2 bind TAGs IEA Canis familiaris 17855 R-CFA-8858252 https://reactome.org/PathwayBrowser/#/R-CFA-8858252 HDLBP binds HDL IEA Canis familiaris 17855 R-CFA-8858270 https://reactome.org/PathwayBrowser/#/R-CFA-8858270 HILPDA binds lipid droplets IEA Canis familiaris 17855 R-CFA-8863471 https://reactome.org/PathwayBrowser/#/R-CFA-8863471 LDLR is bound by DAB2 and ARH IEA Canis familiaris 17855 R-CFA-8865667 https://reactome.org/PathwayBrowser/#/R-CFA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Canis familiaris 17855 R-CFA-8866304 https://reactome.org/PathwayBrowser/#/R-CFA-8866304 pre-VLDL binds lipids to form VLDL IEA Canis familiaris 17855 R-CFA-8866308 https://reactome.org/PathwayBrowser/#/R-CFA-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Canis familiaris 17855 R-CFA-8866321 https://reactome.org/PathwayBrowser/#/R-CFA-8866321 VLDL binds APOC1 and APOC4 IEA Canis familiaris 17855 R-CFA-8866327 https://reactome.org/PathwayBrowser/#/R-CFA-8866327 VLDL translocates from SER lumen to extracellular region IEA Canis familiaris 17855 R-CFA-8866329 https://reactome.org/PathwayBrowser/#/R-CFA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Canis familiaris 17855 R-CFA-8867754 https://reactome.org/PathwayBrowser/#/R-CFA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Canis familiaris 17855 R-CFA-8867756 https://reactome.org/PathwayBrowser/#/R-CFA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Canis familiaris 17855 R-CFA-8868071 https://reactome.org/PathwayBrowser/#/R-CFA-8868071 Clathrin recruits PIK3C2A IEA Canis familiaris 17855 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 17855 R-CFA-8868230 https://reactome.org/PathwayBrowser/#/R-CFA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Canis familiaris 17855 R-CFA-8868236 https://reactome.org/PathwayBrowser/#/R-CFA-8868236 BAR domain proteins recruit dynamin IEA Canis familiaris 17855 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 17855 R-CFA-8868651 https://reactome.org/PathwayBrowser/#/R-CFA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Canis familiaris 17855 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 17855 R-CFA-8868659 https://reactome.org/PathwayBrowser/#/R-CFA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Canis familiaris 17855 R-CFA-8868660 https://reactome.org/PathwayBrowser/#/R-CFA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Canis familiaris 17855 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 17855 R-CFA-8871193 https://reactome.org/PathwayBrowser/#/R-CFA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Canis familiaris 17855 R-CFA-8871194 https://reactome.org/PathwayBrowser/#/R-CFA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Canis familiaris 17855 R-CFA-8876366 https://reactome.org/PathwayBrowser/#/R-CFA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Canis familiaris 17855 R-CFA-8948034 https://reactome.org/PathwayBrowser/#/R-CFA-8948034 FGR binds LDL:LRP8 IEA Canis familiaris 17855 R-CFA-8979996 https://reactome.org/PathwayBrowser/#/R-CFA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Canis familiaris 17855 R-CFA-8980228 https://reactome.org/PathwayBrowser/#/R-CFA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Canis familiaris 17855 R-CFA-9707586 https://reactome.org/PathwayBrowser/#/R-CFA-9707586 FeHM oxidises LDL,HDL IEA Canis familiaris 17855 R-CFA-9737780 https://reactome.org/PathwayBrowser/#/R-CFA-9737780 MTTP binds lomitapide IEA Canis familiaris 17855 R-DDI-1482889 https://reactome.org/PathwayBrowser/#/R-DDI-1482889 DAG is acylated to TAG by DGAT1/2 IEA Dictyostelium discoideum 17855 R-DDI-549192 https://reactome.org/PathwayBrowser/#/R-DDI-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Dictyostelium discoideum 17855 R-DDI-6789310 https://reactome.org/PathwayBrowser/#/R-DDI-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Dictyostelium discoideum 17855 R-DDI-75900 https://reactome.org/PathwayBrowser/#/R-DDI-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Dictyostelium discoideum 17855 R-DDI-8848580 https://reactome.org/PathwayBrowser/#/R-DDI-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Dictyostelium discoideum 17855 R-DDI-8979996 https://reactome.org/PathwayBrowser/#/R-DDI-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Dictyostelium discoideum 17855 R-DME-1482647 https://reactome.org/PathwayBrowser/#/R-DME-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Drosophila melanogaster 17855 R-DME-1482777 https://reactome.org/PathwayBrowser/#/R-DME-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Drosophila melanogaster 17855 R-DME-1482889 https://reactome.org/PathwayBrowser/#/R-DME-1482889 DAG is acylated to TAG by DGAT1/2 IEA Drosophila melanogaster 17855 R-DME-192430 https://reactome.org/PathwayBrowser/#/R-DME-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 17855 R-DME-192475 https://reactome.org/PathwayBrowser/#/R-DME-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Drosophila melanogaster 17855 R-DME-549192 https://reactome.org/PathwayBrowser/#/R-DME-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Drosophila melanogaster 17855 R-DME-5694109 https://reactome.org/PathwayBrowser/#/R-DME-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Drosophila melanogaster 17855 R-DME-75900 https://reactome.org/PathwayBrowser/#/R-DME-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Drosophila melanogaster 17855 R-DME-8848339 https://reactome.org/PathwayBrowser/#/R-DME-8848339 PNPLA5 hydrolyzes TAG IEA Drosophila melanogaster 17855 R-DME-8848580 https://reactome.org/PathwayBrowser/#/R-DME-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Drosophila melanogaster 17855 R-DME-8856630 https://reactome.org/PathwayBrowser/#/R-DME-8856630 CIDEA:CIDEC binds lipid droplets IEA Drosophila melanogaster 17855 R-DME-8857686 https://reactome.org/PathwayBrowser/#/R-DME-8857686 FITM1, FITM2 bind TAGs IEA Drosophila melanogaster 17855 R-DME-8862380 https://reactome.org/PathwayBrowser/#/R-DME-8862380 HSD17B13 binds lipid droplets IEA Drosophila melanogaster 17855 R-DME-8980228 https://reactome.org/PathwayBrowser/#/R-DME-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Drosophila melanogaster 17855 R-DME-9737780 https://reactome.org/PathwayBrowser/#/R-DME-9737780 MTTP binds lomitapide IEA Drosophila melanogaster 17855 R-DRE-1482647 https://reactome.org/PathwayBrowser/#/R-DRE-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Danio rerio 17855 R-DRE-1482777 https://reactome.org/PathwayBrowser/#/R-DRE-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Danio rerio 17855 R-DRE-1482889 https://reactome.org/PathwayBrowser/#/R-DRE-1482889 DAG is acylated to TAG by DGAT1/2 IEA Danio rerio 17855 R-DRE-192430 https://reactome.org/PathwayBrowser/#/R-DRE-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 17855 R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 17855 R-DRE-266299 https://reactome.org/PathwayBrowser/#/R-DRE-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Danio rerio 17855 R-DRE-549192 https://reactome.org/PathwayBrowser/#/R-DRE-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Danio rerio 17855 R-DRE-5694109 https://reactome.org/PathwayBrowser/#/R-DRE-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Danio rerio 17855 R-DRE-6789310 https://reactome.org/PathwayBrowser/#/R-DRE-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Danio rerio 17855 R-DRE-75900 https://reactome.org/PathwayBrowser/#/R-DRE-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Danio rerio 17855 R-DRE-8848339 https://reactome.org/PathwayBrowser/#/R-DRE-8848339 PNPLA5 hydrolyzes TAG IEA Danio rerio 17855 R-DRE-8848580 https://reactome.org/PathwayBrowser/#/R-DRE-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Danio rerio 17855 R-DRE-8857686 https://reactome.org/PathwayBrowser/#/R-DRE-8857686 FITM1, FITM2 bind TAGs IEA Danio rerio 17855 R-DRE-8980228 https://reactome.org/PathwayBrowser/#/R-DRE-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Danio rerio 17855 R-DRE-9737780 https://reactome.org/PathwayBrowser/#/R-DRE-9737780 MTTP binds lomitapide IEA Danio rerio 17855 R-GGA-1482647 https://reactome.org/PathwayBrowser/#/R-GGA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Gallus gallus 17855 R-GGA-1482777 https://reactome.org/PathwayBrowser/#/R-GGA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Gallus gallus 17855 R-GGA-1482889 https://reactome.org/PathwayBrowser/#/R-GGA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Gallus gallus 17855 R-GGA-174587 https://reactome.org/PathwayBrowser/#/R-GGA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Gallus gallus 17855 R-GGA-174786 https://reactome.org/PathwayBrowser/#/R-GGA-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Gallus gallus 17855 R-GGA-192422 https://reactome.org/PathwayBrowser/#/R-GGA-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Gallus gallus 17855 R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 17855 R-GGA-2187332 https://reactome.org/PathwayBrowser/#/R-GGA-2187332 Cytosolic CMs translocate to extracellular region IEA Gallus gallus 17855 R-GGA-2197646 https://reactome.org/PathwayBrowser/#/R-GGA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Gallus gallus 17855 R-GGA-2197770 https://reactome.org/PathwayBrowser/#/R-GGA-2197770 STAB1 (FEEL-1) binds ligands IEA Gallus gallus 17855 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 17855 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 17855 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 17855 R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus 17855 R-GGA-2395764 https://reactome.org/PathwayBrowser/#/R-GGA-2395764 atREs binds to nascent CM IEA Gallus gallus 17855 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 17855 R-GGA-2512800 https://reactome.org/PathwayBrowser/#/R-GGA-2512800 SCARB1:ligand is endocytosed IEA Gallus gallus 17855 R-GGA-266299 https://reactome.org/PathwayBrowser/#/R-GGA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Gallus gallus 17855 R-GGA-266310 https://reactome.org/PathwayBrowser/#/R-GGA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Gallus gallus 17855 R-GGA-266315 https://reactome.org/PathwayBrowser/#/R-GGA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Gallus gallus 17855 R-GGA-266328 https://reactome.org/PathwayBrowser/#/R-GGA-266328 CETP-mediated lipid exchange: spherical HDL gains triacylglycerol IEA Gallus gallus 17855 R-GGA-266350 https://reactome.org/PathwayBrowser/#/R-GGA-266350 CETP-mediated lipid exchange: LDL gains cholesterol ester IEA Gallus gallus 17855 R-GGA-349404 https://reactome.org/PathwayBrowser/#/R-GGA-349404 CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex IEA Gallus gallus 17855 R-GGA-349637 https://reactome.org/PathwayBrowser/#/R-GGA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Gallus gallus 17855 R-GGA-349638 https://reactome.org/PathwayBrowser/#/R-GGA-349638 Disassembly of SR-BI-bound spherical HDL IEA Gallus gallus 17855 R-GGA-432121 https://reactome.org/PathwayBrowser/#/R-GGA-432121 LDL binds to LRP8 IEA Gallus gallus 17855 R-GGA-432129 https://reactome.org/PathwayBrowser/#/R-GGA-432129 FGR binds and phosphorylates LRP8 IEA Gallus gallus 17855 R-GGA-435244 https://reactome.org/PathwayBrowser/#/R-GGA-435244 PECAM1 is phosphorylated IEA Gallus gallus 17855 R-GGA-549192 https://reactome.org/PathwayBrowser/#/R-GGA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Gallus gallus 17855 R-GGA-5694109 https://reactome.org/PathwayBrowser/#/R-GGA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Gallus gallus 17855 R-GGA-6789310 https://reactome.org/PathwayBrowser/#/R-GGA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Gallus gallus 17855 R-GGA-8848338 https://reactome.org/PathwayBrowser/#/R-GGA-8848338 PNPLA4 hydrolyzes TAG IEA Gallus gallus 17855 R-GGA-8848339 https://reactome.org/PathwayBrowser/#/R-GGA-8848339 PNPLA5 hydrolyzes TAG IEA Gallus gallus 17855 R-GGA-8848580 https://reactome.org/PathwayBrowser/#/R-GGA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Gallus gallus 17855 R-GGA-8856630 https://reactome.org/PathwayBrowser/#/R-GGA-8856630 CIDEA:CIDEC binds lipid droplets IEA Gallus gallus 17855 R-GGA-8857686 https://reactome.org/PathwayBrowser/#/R-GGA-8857686 FITM1, FITM2 bind TAGs IEA Gallus gallus 17855 R-GGA-8858252 https://reactome.org/PathwayBrowser/#/R-GGA-8858252 HDLBP binds HDL IEA Gallus gallus 17855 R-GGA-8862380 https://reactome.org/PathwayBrowser/#/R-GGA-8862380 HSD17B13 binds lipid droplets IEA Gallus gallus 17855 R-GGA-8865667 https://reactome.org/PathwayBrowser/#/R-GGA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Gallus gallus 17855 R-GGA-8866304 https://reactome.org/PathwayBrowser/#/R-GGA-8866304 pre-VLDL binds lipids to form VLDL IEA Gallus gallus 17855 R-GGA-8866308 https://reactome.org/PathwayBrowser/#/R-GGA-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Gallus gallus 17855 R-GGA-8866327 https://reactome.org/PathwayBrowser/#/R-GGA-8866327 VLDL translocates from SER lumen to extracellular region IEA Gallus gallus 17855 R-GGA-8866329 https://reactome.org/PathwayBrowser/#/R-GGA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Gallus gallus 17855 R-GGA-8869667 https://reactome.org/PathwayBrowser/#/R-GGA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Gallus gallus 17855 R-GGA-8876366 https://reactome.org/PathwayBrowser/#/R-GGA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Gallus gallus 17855 R-GGA-8948034 https://reactome.org/PathwayBrowser/#/R-GGA-8948034 FGR binds LDL:LRP8 IEA Gallus gallus 17855 R-GGA-8980228 https://reactome.org/PathwayBrowser/#/R-GGA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Gallus gallus 17855 R-GGA-9707586 https://reactome.org/PathwayBrowser/#/R-GGA-9707586 FeHM oxidises LDL,HDL IEA Gallus gallus 17855 R-GGA-9737780 https://reactome.org/PathwayBrowser/#/R-GGA-9737780 MTTP binds lomitapide IEA Gallus gallus 17855 R-HSA-1482647 https://reactome.org/PathwayBrowser/#/R-HSA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 TAS Homo sapiens 17855 R-HSA-1482777 https://reactome.org/PathwayBrowser/#/R-HSA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 TAS Homo sapiens 17855 R-HSA-1482889 https://reactome.org/PathwayBrowser/#/R-HSA-1482889 DAG is acylated to TAG by DGAT1/2 TAS Homo sapiens 17855 R-HSA-163551 https://reactome.org/PathwayBrowser/#/R-HSA-163551 triacylglycerol + H2O -> diacylglycerol + fatty acid IEA Homo sapiens 17855 R-HSA-171059 https://reactome.org/PathwayBrowser/#/R-HSA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] TAS Homo sapiens 17855 R-HSA-171106 https://reactome.org/PathwayBrowser/#/R-HSA-171106 LDLR:LDL complex => LDLR + LDL TAS Homo sapiens 17855 R-HSA-171122 https://reactome.org/PathwayBrowser/#/R-HSA-171122 LDL + LDLR => LDL:LDLR complex TAS Homo sapiens 17855 R-HSA-171141 https://reactome.org/PathwayBrowser/#/R-HSA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) TAS Homo sapiens 17855 R-HSA-174587 https://reactome.org/PathwayBrowser/#/R-HSA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] TAS Homo sapiens 17855 R-HSA-174624 https://reactome.org/PathwayBrowser/#/R-HSA-174624 chylomicron remnant:apoE:LDLR complex => chylomicron remnant:apoE + LDLR IEA Homo sapiens 17855 R-HSA-174657 https://reactome.org/PathwayBrowser/#/R-HSA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex TAS Homo sapiens 17855 R-HSA-174660 https://reactome.org/PathwayBrowser/#/R-HSA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron TAS Homo sapiens 17855 R-HSA-174690 https://reactome.org/PathwayBrowser/#/R-HSA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III TAS Homo sapiens 17855 R-HSA-174706 https://reactome.org/PathwayBrowser/#/R-HSA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) TAS Homo sapiens 17855 R-HSA-174739 https://reactome.org/PathwayBrowser/#/R-HSA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex TAS Homo sapiens 17855 R-HSA-174741 https://reactome.org/PathwayBrowser/#/R-HSA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron TAS Homo sapiens 17855 R-HSA-174757 https://reactome.org/PathwayBrowser/#/R-HSA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols TAS Homo sapiens 17855 R-HSA-174786 https://reactome.org/PathwayBrowser/#/R-HSA-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex TAS Homo sapiens 17855 R-HSA-174808 https://reactome.org/PathwayBrowser/#/R-HSA-174808 chylomicron remnant:apoE:LDLR complex [coated vesicle membrane] => chylomicron remnant:apoE:LDLR complex [endosome membrane] IEA Homo sapiens 17855 R-HSA-176879 https://reactome.org/PathwayBrowser/#/R-HSA-176879 apolipoprotein(a) + LDL => Lp(a) TAS Homo sapiens 17855 R-HSA-192422 https://reactome.org/PathwayBrowser/#/R-HSA-192422 Digestion of triacylglycerols by extracellular PTL:colipase TAS Homo sapiens 17855 R-HSA-192430 https://reactome.org/PathwayBrowser/#/R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 17855 R-HSA-192475 https://reactome.org/PathwayBrowser/#/R-HSA-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 TAS Homo sapiens 17855 R-HSA-203130 https://reactome.org/PathwayBrowser/#/R-HSA-203130 OLR1 binds to oxidized LDL TAS Homo sapiens 17855 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 17855 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 17855 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 17855 R-HSA-2187332 https://reactome.org/PathwayBrowser/#/R-HSA-2187332 Cytosolic CMs translocate to extracellular region TAS Homo sapiens 17855 R-HSA-2197645 https://reactome.org/PathwayBrowser/#/R-HSA-2197645 SCARF1 (SREC-I) binds ligands IEA Homo sapiens 17855 R-HSA-2197646 https://reactome.org/PathwayBrowser/#/R-HSA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands TAS Homo sapiens 17855 R-HSA-2197770 https://reactome.org/PathwayBrowser/#/R-HSA-2197770 STAB1 (FEEL-1) binds ligands TAS Homo sapiens 17855 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 17855 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 17855 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 17855 R-HSA-2247513 https://reactome.org/PathwayBrowser/#/R-HSA-2247513 STAB1:ligand is endocytosed TAS Homo sapiens 17855 R-HSA-2247514 https://reactome.org/PathwayBrowser/#/R-HSA-2247514 SCARF1:ligand is endocytosed TAS Homo sapiens 17855 R-HSA-2395764 https://reactome.org/PathwayBrowser/#/R-HSA-2395764 atREs binds to nascent CM TAS Homo sapiens 17855 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 17855 R-HSA-2395784 https://reactome.org/PathwayBrowser/#/R-HSA-2395784 Nascent CMs transform into mature CMs TAS Homo sapiens 17855 R-HSA-2404131 https://reactome.org/PathwayBrowser/#/R-HSA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol TAS Homo sapiens 17855 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 17855 R-HSA-2423785 https://reactome.org/PathwayBrowser/#/R-HSA-2423785 CR:atREs binds apoE and HSPG TAS Homo sapiens 17855 R-HSA-2424254 https://reactome.org/PathwayBrowser/#/R-HSA-2424254 LDLR transports extracellular CR:atREs to cytosol IEA Homo sapiens 17855 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 17855 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 17855 R-HSA-2512800 https://reactome.org/PathwayBrowser/#/R-HSA-2512800 SCARB1:ligand is endocytosed TAS Homo sapiens 17855 R-HSA-266299 https://reactome.org/PathwayBrowser/#/R-HSA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids TAS Homo sapiens 17855 R-HSA-266303 https://reactome.org/PathwayBrowser/#/R-HSA-266303 Spherical HDL binds C and E apolipoproteins TAS Homo sapiens 17855 R-HSA-266310 https://reactome.org/PathwayBrowser/#/R-HSA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL TAS Homo sapiens 17855 R-HSA-266315 https://reactome.org/PathwayBrowser/#/R-HSA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex TAS Homo sapiens 17855 R-HSA-266328 https://reactome.org/PathwayBrowser/#/R-HSA-266328 CETP-mediated lipid exchange: spherical HDL gains triacylglycerol TAS Homo sapiens 17855 R-HSA-266350 https://reactome.org/PathwayBrowser/#/R-HSA-266350 CETP-mediated lipid exchange: LDL gains cholesterol ester TAS Homo sapiens 17855 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 17855 R-HSA-349404 https://reactome.org/PathwayBrowser/#/R-HSA-349404 CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex TAS Homo sapiens 17855 R-HSA-349637 https://reactome.org/PathwayBrowser/#/R-HSA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface TAS Homo sapiens 17855 R-HSA-349638 https://reactome.org/PathwayBrowser/#/R-HSA-349638 Disassembly of SR-BI-bound spherical HDL TAS Homo sapiens 17855 R-HSA-432121 https://reactome.org/PathwayBrowser/#/R-HSA-432121 LDL binds to LRP8 TAS Homo sapiens 17855 R-HSA-432129 https://reactome.org/PathwayBrowser/#/R-HSA-432129 FGR binds and phosphorylates LRP8 TAS Homo sapiens 17855 R-HSA-435244 https://reactome.org/PathwayBrowser/#/R-HSA-435244 PECAM1 is phosphorylated TAS Homo sapiens 17855 R-HSA-549192 https://reactome.org/PathwayBrowser/#/R-HSA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] TAS Homo sapiens 17855 R-HSA-5694109 https://reactome.org/PathwayBrowser/#/R-HSA-5694109 LIPC dimer hydrolyses TAG to DAG and FA TAS Homo sapiens 17855 R-HSA-6789310 https://reactome.org/PathwayBrowser/#/R-HSA-6789310 LIPs hydrolyse TG to DAG and RCOOH TAS Homo sapiens 17855 R-HSA-75900 https://reactome.org/PathwayBrowser/#/R-HSA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] TAS Homo sapiens 17855 R-HSA-8848338 https://reactome.org/PathwayBrowser/#/R-HSA-8848338 PNPLA4 hydrolyzes TAG TAS Homo sapiens 17855 R-HSA-8848339 https://reactome.org/PathwayBrowser/#/R-HSA-8848339 PNPLA5 hydrolyzes TAG TAS Homo sapiens 17855 R-HSA-8848580 https://reactome.org/PathwayBrowser/#/R-HSA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG TAS Homo sapiens 17855 R-HSA-8854408 https://reactome.org/PathwayBrowser/#/R-HSA-8854408 APOBR dimer binds VLDLs TAS Homo sapiens 17855 R-HSA-8854462 https://reactome.org/PathwayBrowser/#/R-HSA-8854462 VLDLR binds VLDL TAS Homo sapiens 17855 R-HSA-8856630 https://reactome.org/PathwayBrowser/#/R-HSA-8856630 CIDEA:CIDEC binds lipid droplets TAS Homo sapiens 17855 R-HSA-8857686 https://reactome.org/PathwayBrowser/#/R-HSA-8857686 FITM1, FITM2 bind TAGs TAS Homo sapiens 17855 R-HSA-8858252 https://reactome.org/PathwayBrowser/#/R-HSA-8858252 HDLBP binds HDL TAS Homo sapiens 17855 R-HSA-8858270 https://reactome.org/PathwayBrowser/#/R-HSA-8858270 HILPDA binds lipid droplets TAS Homo sapiens 17855 R-HSA-8862380 https://reactome.org/PathwayBrowser/#/R-HSA-8862380 HSD17B13 binds lipid droplets TAS Homo sapiens 17855 R-HSA-8863471 https://reactome.org/PathwayBrowser/#/R-HSA-8863471 LDLR is bound by DAB2 and ARH TAS Homo sapiens 17855 R-HSA-8865667 https://reactome.org/PathwayBrowser/#/R-HSA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids TAS Homo sapiens 17855 R-HSA-8866304 https://reactome.org/PathwayBrowser/#/R-HSA-8866304 pre-VLDL binds lipids to form VLDL TAS Homo sapiens 17855 R-HSA-8866308 https://reactome.org/PathwayBrowser/#/R-HSA-8866308 pre-VLDL translocates from RER membrane to SER lumen TAS Homo sapiens 17855 R-HSA-8866321 https://reactome.org/PathwayBrowser/#/R-HSA-8866321 VLDL binds APOC1 and APOC4 TAS Homo sapiens 17855 R-HSA-8866327 https://reactome.org/PathwayBrowser/#/R-HSA-8866327 VLDL translocates from SER lumen to extracellular region TAS Homo sapiens 17855 R-HSA-8866329 https://reactome.org/PathwayBrowser/#/R-HSA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL TAS Homo sapiens 17855 R-HSA-8867754 https://reactome.org/PathwayBrowser/#/R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit TAS Homo sapiens 17855 R-HSA-8867756 https://reactome.org/PathwayBrowser/#/R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit TAS Homo sapiens 17855 R-HSA-8868071 https://reactome.org/PathwayBrowser/#/R-HSA-8868071 Clathrin recruits PIK3C2A TAS Homo sapiens 17855 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 17855 R-HSA-8868230 https://reactome.org/PathwayBrowser/#/R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery TAS Homo sapiens 17855 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 17855 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 17855 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 17855 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 17855 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 17855 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 17855 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 17855 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 17855 R-HSA-8869667 https://reactome.org/PathwayBrowser/#/R-HSA-8869667 oxLDL:CD36 binds TLR4:TLR6 TAS Homo sapiens 17855 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 17855 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 17855 R-HSA-8876366 https://reactome.org/PathwayBrowser/#/R-HSA-8876366 LDL translocates from endosome lumen to lysosome lumen TAS Homo sapiens 17855 R-HSA-8933258 https://reactome.org/PathwayBrowser/#/R-HSA-8933258 LSR trimer binds LDL IEA Homo sapiens 17855 R-HSA-8933292 https://reactome.org/PathwayBrowser/#/R-HSA-8933292 LSR trimer binds VLDL IEA Homo sapiens 17855 R-HSA-8948034 https://reactome.org/PathwayBrowser/#/R-HSA-8948034 FGR binds LDL:LRP8 TAS Homo sapiens 17855 R-HSA-8979996 https://reactome.org/PathwayBrowser/#/R-HSA-8979996 LIPs hydrolyze TG to DAG and LCFA TAS Homo sapiens 17855 R-HSA-8980228 https://reactome.org/PathwayBrowser/#/R-HSA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA TAS Homo sapiens 17855 R-HSA-9707586 https://reactome.org/PathwayBrowser/#/R-HSA-9707586 FeHM oxidises LDL,HDL TAS Homo sapiens 17855 R-HSA-9737780 https://reactome.org/PathwayBrowser/#/R-HSA-9737780 MTTP binds lomitapide TAS Homo sapiens 17855 R-MMU-1482647 https://reactome.org/PathwayBrowser/#/R-MMU-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Mus musculus 17855 R-MMU-1482777 https://reactome.org/PathwayBrowser/#/R-MMU-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Mus musculus 17855 R-MMU-1482889 https://reactome.org/PathwayBrowser/#/R-MMU-1482889 DAG is acylated to TAG by DGAT1/2 IEA Mus musculus 17855 R-MMU-171059 https://reactome.org/PathwayBrowser/#/R-MMU-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Mus musculus 17855 R-MMU-171106 https://reactome.org/PathwayBrowser/#/R-MMU-171106 LDLR:LDL complex => LDLR + LDL IEA Mus musculus 17855 R-MMU-171122 https://reactome.org/PathwayBrowser/#/R-MMU-171122 LDL + LDLR => LDL:LDLR complex IEA Mus musculus 17855 R-MMU-171141 https://reactome.org/PathwayBrowser/#/R-MMU-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Mus musculus 17855 R-MMU-174587 https://reactome.org/PathwayBrowser/#/R-MMU-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Mus musculus 17855 R-MMU-174657 https://reactome.org/PathwayBrowser/#/R-MMU-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Mus musculus 17855 R-MMU-174660 https://reactome.org/PathwayBrowser/#/R-MMU-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Mus musculus 17855 R-MMU-174690 https://reactome.org/PathwayBrowser/#/R-MMU-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Mus musculus 17855 R-MMU-174706 https://reactome.org/PathwayBrowser/#/R-MMU-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Mus musculus 17855 R-MMU-174739 https://reactome.org/PathwayBrowser/#/R-MMU-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Mus musculus 17855 R-MMU-174741 https://reactome.org/PathwayBrowser/#/R-MMU-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Mus musculus 17855 R-MMU-174757 https://reactome.org/PathwayBrowser/#/R-MMU-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Mus musculus 17855 R-MMU-174786 https://reactome.org/PathwayBrowser/#/R-MMU-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Mus musculus 17855 R-MMU-192422 https://reactome.org/PathwayBrowser/#/R-MMU-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Mus musculus 17855 R-MMU-192430 https://reactome.org/PathwayBrowser/#/R-MMU-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 17855 R-MMU-192475 https://reactome.org/PathwayBrowser/#/R-MMU-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Mus musculus 17855 R-MMU-203130 https://reactome.org/PathwayBrowser/#/R-MMU-203130 OLR1 binds to oxidized LDL IEA Mus musculus 17855 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 17855 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 17855 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 17855 R-MMU-2187332 https://reactome.org/PathwayBrowser/#/R-MMU-2187332 Cytosolic CMs translocate to extracellular region IEA Mus musculus 17855 R-MMU-2197646 https://reactome.org/PathwayBrowser/#/R-MMU-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Mus musculus 17855 R-MMU-2197770 https://reactome.org/PathwayBrowser/#/R-MMU-2197770 STAB1 (FEEL-1) binds ligands IEA Mus musculus 17855 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 17855 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 17855 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 17855 R-MMU-2247513 https://reactome.org/PathwayBrowser/#/R-MMU-2247513 STAB1:ligand is endocytosed IEA Mus musculus 17855 R-MMU-2395764 https://reactome.org/PathwayBrowser/#/R-MMU-2395764 atREs binds to nascent CM IEA Mus musculus 17855 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 17855 R-MMU-2395784 https://reactome.org/PathwayBrowser/#/R-MMU-2395784 Nascent CMs transform into mature CMs IEA Mus musculus 17855 R-MMU-2404131 https://reactome.org/PathwayBrowser/#/R-MMU-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Mus musculus 17855 R-MMU-2423785 https://reactome.org/PathwayBrowser/#/R-MMU-2423785 CR:atREs binds apoE and HSPG IEA Mus musculus 17855 R-MMU-2425403 https://reactome.org/PathwayBrowser/#/R-MMU-2425403 Extracellular CR:atREs are transported to cytosol by Ldlr TAS Mus musculus 17855 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 17855 R-MMU-2512800 https://reactome.org/PathwayBrowser/#/R-MMU-2512800 SCARB1:ligand is endocytosed IEA Mus musculus 17855 R-MMU-266299 https://reactome.org/PathwayBrowser/#/R-MMU-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Mus musculus 17855 R-MMU-266303 https://reactome.org/PathwayBrowser/#/R-MMU-266303 Spherical HDL binds C and E apolipoproteins IEA Mus musculus 17855 R-MMU-266310 https://reactome.org/PathwayBrowser/#/R-MMU-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Mus musculus 17855 R-MMU-266315 https://reactome.org/PathwayBrowser/#/R-MMU-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Mus musculus 17855 R-MMU-349637 https://reactome.org/PathwayBrowser/#/R-MMU-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Mus musculus 17855 R-MMU-349638 https://reactome.org/PathwayBrowser/#/R-MMU-349638 Disassembly of SR-BI-bound spherical HDL IEA Mus musculus 17855 R-MMU-432121 https://reactome.org/PathwayBrowser/#/R-MMU-432121 LDL binds to LRP8 IEA Mus musculus 17855 R-MMU-432129 https://reactome.org/PathwayBrowser/#/R-MMU-432129 FGR binds and phosphorylates LRP8 IEA Mus musculus 17855 R-MMU-435244 https://reactome.org/PathwayBrowser/#/R-MMU-435244 PECAM1 is phosphorylated IEA Mus musculus 17855 R-MMU-549192 https://reactome.org/PathwayBrowser/#/R-MMU-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Mus musculus 17855 R-MMU-5694109 https://reactome.org/PathwayBrowser/#/R-MMU-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Mus musculus 17855 R-MMU-6789310 https://reactome.org/PathwayBrowser/#/R-MMU-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Mus musculus 17855 R-MMU-75900 https://reactome.org/PathwayBrowser/#/R-MMU-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Mus musculus 17855 R-MMU-8848339 https://reactome.org/PathwayBrowser/#/R-MMU-8848339 PNPLA5 hydrolyzes TAG IEA Mus musculus 17855 R-MMU-8848580 https://reactome.org/PathwayBrowser/#/R-MMU-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Mus musculus 17855 R-MMU-8854408 https://reactome.org/PathwayBrowser/#/R-MMU-8854408 APOBR dimer binds VLDLs IEA Mus musculus 17855 R-MMU-8854462 https://reactome.org/PathwayBrowser/#/R-MMU-8854462 VLDLR binds VLDL IEA Mus musculus 17855 R-MMU-8856630 https://reactome.org/PathwayBrowser/#/R-MMU-8856630 CIDEA:CIDEC binds lipid droplets IEA Mus musculus 17855 R-MMU-8857686 https://reactome.org/PathwayBrowser/#/R-MMU-8857686 FITM1, FITM2 bind TAGs IEA Mus musculus 17855 R-MMU-8858252 https://reactome.org/PathwayBrowser/#/R-MMU-8858252 HDLBP binds HDL IEA Mus musculus 17855 R-MMU-8858270 https://reactome.org/PathwayBrowser/#/R-MMU-8858270 HILPDA binds lipid droplets IEA Mus musculus 17855 R-MMU-8862380 https://reactome.org/PathwayBrowser/#/R-MMU-8862380 HSD17B13 binds lipid droplets IEA Mus musculus 17855 R-MMU-8863471 https://reactome.org/PathwayBrowser/#/R-MMU-8863471 LDLR is bound by DAB2 and ARH IEA Mus musculus 17855 R-MMU-8865667 https://reactome.org/PathwayBrowser/#/R-MMU-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Mus musculus 17855 R-MMU-8866304 https://reactome.org/PathwayBrowser/#/R-MMU-8866304 pre-VLDL binds lipids to form VLDL IEA Mus musculus 17855 R-MMU-8866308 https://reactome.org/PathwayBrowser/#/R-MMU-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Mus musculus 17855 R-MMU-8866321 https://reactome.org/PathwayBrowser/#/R-MMU-8866321 VLDL binds APOC1 and APOC4 IEA Mus musculus 17855 R-MMU-8866327 https://reactome.org/PathwayBrowser/#/R-MMU-8866327 VLDL translocates from SER lumen to extracellular region IEA Mus musculus 17855 R-MMU-8866329 https://reactome.org/PathwayBrowser/#/R-MMU-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Mus musculus 17855 R-MMU-8867754 https://reactome.org/PathwayBrowser/#/R-MMU-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Mus musculus 17855 R-MMU-8867756 https://reactome.org/PathwayBrowser/#/R-MMU-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Mus musculus 17855 R-MMU-8868071 https://reactome.org/PathwayBrowser/#/R-MMU-8868071 Clathrin recruits PIK3C2A IEA Mus musculus 17855 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 17855 R-MMU-8868236 https://reactome.org/PathwayBrowser/#/R-MMU-8868236 BAR domain proteins recruit dynamin IEA Mus musculus 17855 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 17855 R-MMU-8868651 https://reactome.org/PathwayBrowser/#/R-MMU-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Mus musculus 17855 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 17855 R-MMU-8868659 https://reactome.org/PathwayBrowser/#/R-MMU-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Mus musculus 17855 R-MMU-8868660 https://reactome.org/PathwayBrowser/#/R-MMU-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Mus musculus 17855 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 17855 R-MMU-8869667 https://reactome.org/PathwayBrowser/#/R-MMU-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Mus musculus 17855 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 17855 R-MMU-8871194 https://reactome.org/PathwayBrowser/#/R-MMU-8871194 RAB5 and GAPVD1 bind AP-2 IEA Mus musculus 17855 R-MMU-8876366 https://reactome.org/PathwayBrowser/#/R-MMU-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Mus musculus 17855 R-MMU-8933256 https://reactome.org/PathwayBrowser/#/R-MMU-8933256 Lsr trimer binds LDL TAS Mus musculus 17855 R-MMU-8933295 https://reactome.org/PathwayBrowser/#/R-MMU-8933295 Lsr trimer binds VLDL TAS Mus musculus 17855 R-MMU-8948034 https://reactome.org/PathwayBrowser/#/R-MMU-8948034 FGR binds LDL:LRP8 IEA Mus musculus 17855 R-MMU-8979996 https://reactome.org/PathwayBrowser/#/R-MMU-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Mus musculus 17855 R-MMU-8980228 https://reactome.org/PathwayBrowser/#/R-MMU-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Mus musculus 17855 R-MMU-9707586 https://reactome.org/PathwayBrowser/#/R-MMU-9707586 FeHM oxidises LDL,HDL IEA Mus musculus 17855 R-MMU-9737780 https://reactome.org/PathwayBrowser/#/R-MMU-9737780 MTTP binds lomitapide IEA Mus musculus 17855 R-PFA-1482647 https://reactome.org/PathwayBrowser/#/R-PFA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Plasmodium falciparum 17855 R-PFA-1482777 https://reactome.org/PathwayBrowser/#/R-PFA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Plasmodium falciparum 17855 R-PFA-1482889 https://reactome.org/PathwayBrowser/#/R-PFA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Plasmodium falciparum 17855 R-PFA-6789310 https://reactome.org/PathwayBrowser/#/R-PFA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Plasmodium falciparum 17855 R-PFA-75900 https://reactome.org/PathwayBrowser/#/R-PFA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Plasmodium falciparum 17855 R-PFA-8848338 https://reactome.org/PathwayBrowser/#/R-PFA-8848338 PNPLA4 hydrolyzes TAG IEA Plasmodium falciparum 17855 R-PFA-8848339 https://reactome.org/PathwayBrowser/#/R-PFA-8848339 PNPLA5 hydrolyzes TAG IEA Plasmodium falciparum 17855 R-PFA-8979996 https://reactome.org/PathwayBrowser/#/R-PFA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Plasmodium falciparum 17855 R-RNO-1482647 https://reactome.org/PathwayBrowser/#/R-RNO-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Rattus norvegicus 17855 R-RNO-1482777 https://reactome.org/PathwayBrowser/#/R-RNO-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Rattus norvegicus 17855 R-RNO-1482889 https://reactome.org/PathwayBrowser/#/R-RNO-1482889 DAG is acylated to TAG by DGAT1/2 IEA Rattus norvegicus 17855 R-RNO-163515 https://reactome.org/PathwayBrowser/#/R-RNO-163515 triacylglycerol + H2O -> diacylglycerol + fatty acid TAS Rattus norvegicus 17855 R-RNO-171059 https://reactome.org/PathwayBrowser/#/R-RNO-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Rattus norvegicus 17855 R-RNO-171106 https://reactome.org/PathwayBrowser/#/R-RNO-171106 LDLR:LDL complex => LDLR + LDL IEA Rattus norvegicus 17855 R-RNO-171122 https://reactome.org/PathwayBrowser/#/R-RNO-171122 LDL + LDLR => LDL:LDLR complex IEA Rattus norvegicus 17855 R-RNO-171141 https://reactome.org/PathwayBrowser/#/R-RNO-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Rattus norvegicus 17855 R-RNO-174587 https://reactome.org/PathwayBrowser/#/R-RNO-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Rattus norvegicus 17855 R-RNO-174657 https://reactome.org/PathwayBrowser/#/R-RNO-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Rattus norvegicus 17855 R-RNO-174660 https://reactome.org/PathwayBrowser/#/R-RNO-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Rattus norvegicus 17855 R-RNO-174690 https://reactome.org/PathwayBrowser/#/R-RNO-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Rattus norvegicus 17855 R-RNO-174706 https://reactome.org/PathwayBrowser/#/R-RNO-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Rattus norvegicus 17855 R-RNO-174739 https://reactome.org/PathwayBrowser/#/R-RNO-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Rattus norvegicus 17855 R-RNO-174741 https://reactome.org/PathwayBrowser/#/R-RNO-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Rattus norvegicus 17855 R-RNO-174757 https://reactome.org/PathwayBrowser/#/R-RNO-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Rattus norvegicus 17855 R-RNO-174786 https://reactome.org/PathwayBrowser/#/R-RNO-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Rattus norvegicus 17855 R-RNO-192422 https://reactome.org/PathwayBrowser/#/R-RNO-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Rattus norvegicus 17855 R-RNO-192430 https://reactome.org/PathwayBrowser/#/R-RNO-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 17855 R-RNO-192475 https://reactome.org/PathwayBrowser/#/R-RNO-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Rattus norvegicus 17855 R-RNO-203130 https://reactome.org/PathwayBrowser/#/R-RNO-203130 OLR1 binds to oxidized LDL IEA Rattus norvegicus 17855 R-RNO-2187332 https://reactome.org/PathwayBrowser/#/R-RNO-2187332 Cytosolic CMs translocate to extracellular region IEA Rattus norvegicus 17855 R-RNO-2197646 https://reactome.org/PathwayBrowser/#/R-RNO-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Rattus norvegicus 17855 R-RNO-2197770 https://reactome.org/PathwayBrowser/#/R-RNO-2197770 STAB1 (FEEL-1) binds ligands IEA Rattus norvegicus 17855 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 17855 R-RNO-2247513 https://reactome.org/PathwayBrowser/#/R-RNO-2247513 STAB1:ligand is endocytosed IEA Rattus norvegicus 17855 R-RNO-2395764 https://reactome.org/PathwayBrowser/#/R-RNO-2395764 atREs binds to nascent CM IEA Rattus norvegicus 17855 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 17855 R-RNO-2395784 https://reactome.org/PathwayBrowser/#/R-RNO-2395784 Nascent CMs transform into mature CMs IEA Rattus norvegicus 17855 R-RNO-2404131 https://reactome.org/PathwayBrowser/#/R-RNO-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Rattus norvegicus 17855 R-RNO-2423785 https://reactome.org/PathwayBrowser/#/R-RNO-2423785 CR:atREs binds apoE and HSPG IEA Rattus norvegicus 17855 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 17855 R-RNO-2512800 https://reactome.org/PathwayBrowser/#/R-RNO-2512800 SCARB1:ligand is endocytosed IEA Rattus norvegicus 17855 R-RNO-266299 https://reactome.org/PathwayBrowser/#/R-RNO-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Rattus norvegicus 17855 R-RNO-266303 https://reactome.org/PathwayBrowser/#/R-RNO-266303 Spherical HDL binds C and E apolipoproteins IEA Rattus norvegicus 17855 R-RNO-266310 https://reactome.org/PathwayBrowser/#/R-RNO-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Rattus norvegicus 17855 R-RNO-266315 https://reactome.org/PathwayBrowser/#/R-RNO-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Rattus norvegicus 17855 R-RNO-349637 https://reactome.org/PathwayBrowser/#/R-RNO-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Rattus norvegicus 17855 R-RNO-349638 https://reactome.org/PathwayBrowser/#/R-RNO-349638 Disassembly of SR-BI-bound spherical HDL IEA Rattus norvegicus 17855 R-RNO-432121 https://reactome.org/PathwayBrowser/#/R-RNO-432121 LDL binds to LRP8 IEA Rattus norvegicus 17855 R-RNO-432129 https://reactome.org/PathwayBrowser/#/R-RNO-432129 FGR binds and phosphorylates LRP8 IEA Rattus norvegicus 17855 R-RNO-435244 https://reactome.org/PathwayBrowser/#/R-RNO-435244 PECAM1 is phosphorylated IEA Rattus norvegicus 17855 R-RNO-549192 https://reactome.org/PathwayBrowser/#/R-RNO-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Rattus norvegicus 17855 R-RNO-5694109 https://reactome.org/PathwayBrowser/#/R-RNO-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Rattus norvegicus 17855 R-RNO-6789310 https://reactome.org/PathwayBrowser/#/R-RNO-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Rattus norvegicus 17855 R-RNO-75900 https://reactome.org/PathwayBrowser/#/R-RNO-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Rattus norvegicus 17855 R-RNO-8848338 https://reactome.org/PathwayBrowser/#/R-RNO-8848338 PNPLA4 hydrolyzes TAG IEA Rattus norvegicus 17855 R-RNO-8848339 https://reactome.org/PathwayBrowser/#/R-RNO-8848339 PNPLA5 hydrolyzes TAG IEA Rattus norvegicus 17855 R-RNO-8848580 https://reactome.org/PathwayBrowser/#/R-RNO-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Rattus norvegicus 17855 R-RNO-8854408 https://reactome.org/PathwayBrowser/#/R-RNO-8854408 APOBR dimer binds VLDLs IEA Rattus norvegicus 17855 R-RNO-8854462 https://reactome.org/PathwayBrowser/#/R-RNO-8854462 VLDLR binds VLDL IEA Rattus norvegicus 17855 R-RNO-8856630 https://reactome.org/PathwayBrowser/#/R-RNO-8856630 CIDEA:CIDEC binds lipid droplets IEA Rattus norvegicus 17855 R-RNO-8857686 https://reactome.org/PathwayBrowser/#/R-RNO-8857686 FITM1, FITM2 bind TAGs IEA Rattus norvegicus 17855 R-RNO-8858252 https://reactome.org/PathwayBrowser/#/R-RNO-8858252 HDLBP binds HDL IEA Rattus norvegicus 17855 R-RNO-8862380 https://reactome.org/PathwayBrowser/#/R-RNO-8862380 HSD17B13 binds lipid droplets IEA Rattus norvegicus 17855 R-RNO-8863471 https://reactome.org/PathwayBrowser/#/R-RNO-8863471 LDLR is bound by DAB2 and ARH IEA Rattus norvegicus 17855 R-RNO-8865667 https://reactome.org/PathwayBrowser/#/R-RNO-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Rattus norvegicus 17855 R-RNO-8866304 https://reactome.org/PathwayBrowser/#/R-RNO-8866304 pre-VLDL binds lipids to form VLDL IEA Rattus norvegicus 17855 R-RNO-8866308 https://reactome.org/PathwayBrowser/#/R-RNO-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Rattus norvegicus 17855 R-RNO-8866321 https://reactome.org/PathwayBrowser/#/R-RNO-8866321 VLDL binds APOC1 and APOC4 IEA Rattus norvegicus 17855 R-RNO-8866327 https://reactome.org/PathwayBrowser/#/R-RNO-8866327 VLDL translocates from SER lumen to extracellular region IEA Rattus norvegicus 17855 R-RNO-8866329 https://reactome.org/PathwayBrowser/#/R-RNO-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Rattus norvegicus 17855 R-RNO-8867754 https://reactome.org/PathwayBrowser/#/R-RNO-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Rattus norvegicus 17855 R-RNO-8867756 https://reactome.org/PathwayBrowser/#/R-RNO-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Rattus norvegicus 17855 R-RNO-8868071 https://reactome.org/PathwayBrowser/#/R-RNO-8868071 Clathrin recruits PIK3C2A IEA Rattus norvegicus 17855 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 17855 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus 17855 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 17855 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus 17855 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 17855 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus 17855 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus 17855 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 17855 R-RNO-8869667 https://reactome.org/PathwayBrowser/#/R-RNO-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Rattus norvegicus 17855 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 17855 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus 17855 R-RNO-8876366 https://reactome.org/PathwayBrowser/#/R-RNO-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Rattus norvegicus 17855 R-RNO-8948034 https://reactome.org/PathwayBrowser/#/R-RNO-8948034 FGR binds LDL:LRP8 IEA Rattus norvegicus 17855 R-RNO-8979996 https://reactome.org/PathwayBrowser/#/R-RNO-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Rattus norvegicus 17855 R-RNO-8980228 https://reactome.org/PathwayBrowser/#/R-RNO-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Rattus norvegicus 17855 R-RNO-9707586 https://reactome.org/PathwayBrowser/#/R-RNO-9707586 FeHM oxidises LDL,HDL IEA Rattus norvegicus 17855 R-RNO-9737780 https://reactome.org/PathwayBrowser/#/R-RNO-9737780 MTTP binds lomitapide IEA Rattus norvegicus 17855 R-SCE-1482889 https://reactome.org/PathwayBrowser/#/R-SCE-1482889 DAG is acylated to TAG by DGAT1/2 IEA Saccharomyces cerevisiae 17855 R-SCE-549192 https://reactome.org/PathwayBrowser/#/R-SCE-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Saccharomyces cerevisiae 17855 R-SCE-6789310 https://reactome.org/PathwayBrowser/#/R-SCE-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Saccharomyces cerevisiae 17855 R-SCE-8848580 https://reactome.org/PathwayBrowser/#/R-SCE-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Saccharomyces cerevisiae 17855 R-SCE-8857686 https://reactome.org/PathwayBrowser/#/R-SCE-8857686 FITM1, FITM2 bind TAGs IEA Saccharomyces cerevisiae 17855 R-SCE-8862380 https://reactome.org/PathwayBrowser/#/R-SCE-8862380 HSD17B13 binds lipid droplets IEA Saccharomyces cerevisiae 17855 R-SCE-8979996 https://reactome.org/PathwayBrowser/#/R-SCE-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Saccharomyces cerevisiae 17855 R-SPO-1482889 https://reactome.org/PathwayBrowser/#/R-SPO-1482889 DAG is acylated to TAG by DGAT1/2 IEA Schizosaccharomyces pombe 17855 R-SPO-549192 https://reactome.org/PathwayBrowser/#/R-SPO-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Schizosaccharomyces pombe 17855 R-SPO-6789310 https://reactome.org/PathwayBrowser/#/R-SPO-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Schizosaccharomyces pombe 17855 R-SPO-8848580 https://reactome.org/PathwayBrowser/#/R-SPO-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Schizosaccharomyces pombe 17855 R-SPO-8857686 https://reactome.org/PathwayBrowser/#/R-SPO-8857686 FITM1, FITM2 bind TAGs IEA Schizosaccharomyces pombe 17855 R-SPO-8979996 https://reactome.org/PathwayBrowser/#/R-SPO-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Schizosaccharomyces pombe 17855 R-SSC-1482647 https://reactome.org/PathwayBrowser/#/R-SSC-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Sus scrofa 17855 R-SSC-1482777 https://reactome.org/PathwayBrowser/#/R-SSC-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Sus scrofa 17855 R-SSC-1482889 https://reactome.org/PathwayBrowser/#/R-SSC-1482889 DAG is acylated to TAG by DGAT1/2 IEA Sus scrofa 17855 R-SSC-171059 https://reactome.org/PathwayBrowser/#/R-SSC-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Sus scrofa 17855 R-SSC-171106 https://reactome.org/PathwayBrowser/#/R-SSC-171106 LDLR:LDL complex => LDLR + LDL IEA Sus scrofa 17855 R-SSC-171122 https://reactome.org/PathwayBrowser/#/R-SSC-171122 LDL + LDLR => LDL:LDLR complex IEA Sus scrofa 17855 R-SSC-171141 https://reactome.org/PathwayBrowser/#/R-SSC-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Sus scrofa 17855 R-SSC-174587 https://reactome.org/PathwayBrowser/#/R-SSC-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Sus scrofa 17855 R-SSC-174657 https://reactome.org/PathwayBrowser/#/R-SSC-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Sus scrofa 17855 R-SSC-174660 https://reactome.org/PathwayBrowser/#/R-SSC-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Sus scrofa 17855 R-SSC-174690 https://reactome.org/PathwayBrowser/#/R-SSC-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Sus scrofa 17855 R-SSC-174706 https://reactome.org/PathwayBrowser/#/R-SSC-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Sus scrofa 17855 R-SSC-174739 https://reactome.org/PathwayBrowser/#/R-SSC-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Sus scrofa 17855 R-SSC-174741 https://reactome.org/PathwayBrowser/#/R-SSC-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Sus scrofa 17855 R-SSC-174757 https://reactome.org/PathwayBrowser/#/R-SSC-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Sus scrofa 17855 R-SSC-174786 https://reactome.org/PathwayBrowser/#/R-SSC-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Sus scrofa 17855 R-SSC-192422 https://reactome.org/PathwayBrowser/#/R-SSC-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Sus scrofa 17855 R-SSC-192430 https://reactome.org/PathwayBrowser/#/R-SSC-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 17855 R-SSC-192475 https://reactome.org/PathwayBrowser/#/R-SSC-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Sus scrofa 17855 R-SSC-203130 https://reactome.org/PathwayBrowser/#/R-SSC-203130 OLR1 binds to oxidized LDL IEA Sus scrofa 17855 R-SSC-2187332 https://reactome.org/PathwayBrowser/#/R-SSC-2187332 Cytosolic CMs translocate to extracellular region IEA Sus scrofa 17855 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa 17855 R-SSC-2197770 https://reactome.org/PathwayBrowser/#/R-SSC-2197770 STAB1 (FEEL-1) binds ligands IEA Sus scrofa 17855 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 17855 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 17855 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 17855 R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa 17855 R-SSC-2395764 https://reactome.org/PathwayBrowser/#/R-SSC-2395764 atREs binds to nascent CM IEA Sus scrofa 17855 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 17855 R-SSC-2395784 https://reactome.org/PathwayBrowser/#/R-SSC-2395784 Nascent CMs transform into mature CMs IEA Sus scrofa 17855 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa 17855 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa 17855 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 17855 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa 17855 R-SSC-266299 https://reactome.org/PathwayBrowser/#/R-SSC-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Sus scrofa 17855 R-SSC-266303 https://reactome.org/PathwayBrowser/#/R-SSC-266303 Spherical HDL binds C and E apolipoproteins IEA Sus scrofa 17855 R-SSC-266310 https://reactome.org/PathwayBrowser/#/R-SSC-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Sus scrofa 17855 R-SSC-266315 https://reactome.org/PathwayBrowser/#/R-SSC-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Sus scrofa 17855 R-SSC-349637 https://reactome.org/PathwayBrowser/#/R-SSC-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Sus scrofa 17855 R-SSC-349638 https://reactome.org/PathwayBrowser/#/R-SSC-349638 Disassembly of SR-BI-bound spherical HDL IEA Sus scrofa 17855 R-SSC-432121 https://reactome.org/PathwayBrowser/#/R-SSC-432121 LDL binds to LRP8 IEA Sus scrofa 17855 R-SSC-432129 https://reactome.org/PathwayBrowser/#/R-SSC-432129 FGR binds and phosphorylates LRP8 IEA Sus scrofa 17855 R-SSC-435244 https://reactome.org/PathwayBrowser/#/R-SSC-435244 PECAM1 is phosphorylated IEA Sus scrofa 17855 R-SSC-549192 https://reactome.org/PathwayBrowser/#/R-SSC-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Sus scrofa 17855 R-SSC-5694109 https://reactome.org/PathwayBrowser/#/R-SSC-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Sus scrofa 17855 R-SSC-6789310 https://reactome.org/PathwayBrowser/#/R-SSC-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Sus scrofa 17855 R-SSC-75900 https://reactome.org/PathwayBrowser/#/R-SSC-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Sus scrofa 17855 R-SSC-8848338 https://reactome.org/PathwayBrowser/#/R-SSC-8848338 PNPLA4 hydrolyzes TAG IEA Sus scrofa 17855 R-SSC-8848580 https://reactome.org/PathwayBrowser/#/R-SSC-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Sus scrofa 17855 R-SSC-8856630 https://reactome.org/PathwayBrowser/#/R-SSC-8856630 CIDEA:CIDEC binds lipid droplets IEA Sus scrofa 17855 R-SSC-8857686 https://reactome.org/PathwayBrowser/#/R-SSC-8857686 FITM1, FITM2 bind TAGs IEA Sus scrofa 17855 R-SSC-8858252 https://reactome.org/PathwayBrowser/#/R-SSC-8858252 HDLBP binds HDL IEA Sus scrofa 17855 R-SSC-8858270 https://reactome.org/PathwayBrowser/#/R-SSC-8858270 HILPDA binds lipid droplets IEA Sus scrofa 17855 R-SSC-8862380 https://reactome.org/PathwayBrowser/#/R-SSC-8862380 HSD17B13 binds lipid droplets IEA Sus scrofa 17855 R-SSC-8863471 https://reactome.org/PathwayBrowser/#/R-SSC-8863471 LDLR is bound by DAB2 and ARH IEA Sus scrofa 17855 R-SSC-8865667 https://reactome.org/PathwayBrowser/#/R-SSC-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Sus scrofa 17855 R-SSC-8866304 https://reactome.org/PathwayBrowser/#/R-SSC-8866304 pre-VLDL binds lipids to form VLDL IEA Sus scrofa 17855 R-SSC-8866308 https://reactome.org/PathwayBrowser/#/R-SSC-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Sus scrofa 17855 R-SSC-8866327 https://reactome.org/PathwayBrowser/#/R-SSC-8866327 VLDL translocates from SER lumen to extracellular region IEA Sus scrofa 17855 R-SSC-8866329 https://reactome.org/PathwayBrowser/#/R-SSC-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Sus scrofa 17855 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa 17855 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa 17855 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa 17855 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 17855 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa 17855 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa 17855 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 17855 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa 17855 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 17855 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa 17855 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa 17855 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 17855 R-SSC-8869667 https://reactome.org/PathwayBrowser/#/R-SSC-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Sus scrofa 17855 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 17855 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa 17855 R-SSC-8876366 https://reactome.org/PathwayBrowser/#/R-SSC-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Sus scrofa 17855 R-SSC-8948034 https://reactome.org/PathwayBrowser/#/R-SSC-8948034 FGR binds LDL:LRP8 IEA Sus scrofa 17855 R-SSC-8980228 https://reactome.org/PathwayBrowser/#/R-SSC-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Sus scrofa 17855 R-SSC-9707586 https://reactome.org/PathwayBrowser/#/R-SSC-9707586 FeHM oxidises LDL,HDL IEA Sus scrofa 17855 R-SSC-9737780 https://reactome.org/PathwayBrowser/#/R-SSC-9737780 MTTP binds lomitapide IEA Sus scrofa 17855 R-XTR-1482647 https://reactome.org/PathwayBrowser/#/R-XTR-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Xenopus tropicalis 17855 R-XTR-1482777 https://reactome.org/PathwayBrowser/#/R-XTR-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Xenopus tropicalis 17855 R-XTR-1482889 https://reactome.org/PathwayBrowser/#/R-XTR-1482889 DAG is acylated to TAG by DGAT1/2 IEA Xenopus tropicalis 17855 R-XTR-192422 https://reactome.org/PathwayBrowser/#/R-XTR-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis 17855 R-XTR-192430 https://reactome.org/PathwayBrowser/#/R-XTR-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 17855 R-XTR-549192 https://reactome.org/PathwayBrowser/#/R-XTR-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Xenopus tropicalis 17855 R-XTR-5694109 https://reactome.org/PathwayBrowser/#/R-XTR-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Xenopus tropicalis 17855 R-XTR-75900 https://reactome.org/PathwayBrowser/#/R-XTR-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Xenopus tropicalis 17855 R-XTR-8848338 https://reactome.org/PathwayBrowser/#/R-XTR-8848338 PNPLA4 hydrolyzes TAG IEA Xenopus tropicalis 17855 R-XTR-8848339 https://reactome.org/PathwayBrowser/#/R-XTR-8848339 PNPLA5 hydrolyzes TAG IEA Xenopus tropicalis 17855 R-XTR-8848580 https://reactome.org/PathwayBrowser/#/R-XTR-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Xenopus tropicalis 17855 R-XTR-8856630 https://reactome.org/PathwayBrowser/#/R-XTR-8856630 CIDEA:CIDEC binds lipid droplets IEA Xenopus tropicalis 17855 R-XTR-8857686 https://reactome.org/PathwayBrowser/#/R-XTR-8857686 FITM1, FITM2 bind TAGs IEA Xenopus tropicalis 17855 R-XTR-8862380 https://reactome.org/PathwayBrowser/#/R-XTR-8862380 HSD17B13 binds lipid droplets IEA Xenopus tropicalis 17855 R-XTR-8980228 https://reactome.org/PathwayBrowser/#/R-XTR-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Xenopus tropicalis 17855 R-XTR-9737780 https://reactome.org/PathwayBrowser/#/R-XTR-9737780 MTTP binds lomitapide IEA Xenopus tropicalis 17862 R-GGA-433550 https://reactome.org/PathwayBrowser/#/R-GGA-433550 palmitoyl-CoA + serine => 3-dehydrosphinganine + CoASH + CO2 IEA Gallus gallus 17862 R-GGA-433576 https://reactome.org/PathwayBrowser/#/R-GGA-433576 3-dehydrosphinganine + NADPH + H+ => sphinganine + NADP+ IEA Gallus gallus 17864 R-BTA-176604 https://reactome.org/PathwayBrowser/#/R-BTA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Bos taurus 17864 R-BTA-433089 https://reactome.org/PathwayBrowser/#/R-BTA-433089 SOAT can transport taurolithocholate-3-sulphate IEA Bos taurus 17864 R-CEL-433089 https://reactome.org/PathwayBrowser/#/R-CEL-433089 SOAT can transport taurolithocholate-3-sulphate IEA Caenorhabditis elegans 17864 R-CFA-433089 https://reactome.org/PathwayBrowser/#/R-CFA-433089 SOAT can transport taurolithocholate-3-sulphate IEA Canis familiaris 17864 R-DME-176604 https://reactome.org/PathwayBrowser/#/R-DME-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Drosophila melanogaster 17864 R-DME-433089 https://reactome.org/PathwayBrowser/#/R-DME-433089 SOAT can transport taurolithocholate-3-sulphate IEA Drosophila melanogaster 17864 R-DRE-176604 https://reactome.org/PathwayBrowser/#/R-DRE-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Danio rerio 17864 R-GGA-176604 https://reactome.org/PathwayBrowser/#/R-GGA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Gallus gallus 17864 R-HSA-176604 https://reactome.org/PathwayBrowser/#/R-HSA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP TAS Homo sapiens 17864 R-HSA-433089 https://reactome.org/PathwayBrowser/#/R-HSA-433089 SOAT can transport taurolithocholate-3-sulphate TAS Homo sapiens 17864 R-MMU-176604 https://reactome.org/PathwayBrowser/#/R-MMU-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Mus musculus 17864 R-MMU-433089 https://reactome.org/PathwayBrowser/#/R-MMU-433089 SOAT can transport taurolithocholate-3-sulphate IEA Mus musculus 17864 R-RNO-176604 https://reactome.org/PathwayBrowser/#/R-RNO-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Rattus norvegicus 17864 R-RNO-433089 https://reactome.org/PathwayBrowser/#/R-RNO-433089 SOAT can transport taurolithocholate-3-sulphate IEA Rattus norvegicus 17864 R-SSC-176604 https://reactome.org/PathwayBrowser/#/R-SSC-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Sus scrofa 17864 R-SSC-433089 https://reactome.org/PathwayBrowser/#/R-SSC-433089 SOAT can transport taurolithocholate-3-sulphate IEA Sus scrofa 17864 R-XTR-176604 https://reactome.org/PathwayBrowser/#/R-XTR-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Xenopus tropicalis 17864 R-XTR-433089 https://reactome.org/PathwayBrowser/#/R-XTR-433089 SOAT can transport taurolithocholate-3-sulphate IEA Xenopus tropicalis 17865 R-BTA-508179 https://reactome.org/PathwayBrowser/#/R-BTA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Bos taurus 17865 R-BTA-508189 https://reactome.org/PathwayBrowser/#/R-BTA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Bos taurus 17865 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 17865 R-BTA-70723 https://reactome.org/PathwayBrowser/#/R-BTA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Bos taurus 17865 R-BTA-70724 https://reactome.org/PathwayBrowser/#/R-BTA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Bos taurus 17865 R-CEL-508179 https://reactome.org/PathwayBrowser/#/R-CEL-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Caenorhabditis elegans 17865 R-CEL-508189 https://reactome.org/PathwayBrowser/#/R-CEL-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Caenorhabditis elegans 17865 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 17865 R-CEL-70723 https://reactome.org/PathwayBrowser/#/R-CEL-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Caenorhabditis elegans 17865 R-CEL-70724 https://reactome.org/PathwayBrowser/#/R-CEL-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Caenorhabditis elegans 17865 R-CFA-508179 https://reactome.org/PathwayBrowser/#/R-CFA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Canis familiaris 17865 R-CFA-508189 https://reactome.org/PathwayBrowser/#/R-CFA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Canis familiaris 17865 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 17865 R-CFA-70723 https://reactome.org/PathwayBrowser/#/R-CFA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Canis familiaris 17865 R-CFA-70724 https://reactome.org/PathwayBrowser/#/R-CFA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Canis familiaris 17865 R-DDI-508179 https://reactome.org/PathwayBrowser/#/R-DDI-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Dictyostelium discoideum 17865 R-DDI-508189 https://reactome.org/PathwayBrowser/#/R-DDI-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Dictyostelium discoideum 17865 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 17865 R-DDI-70723 https://reactome.org/PathwayBrowser/#/R-DDI-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Dictyostelium discoideum 17865 R-DDI-70724 https://reactome.org/PathwayBrowser/#/R-DDI-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Dictyostelium discoideum 17865 R-DME-508179 https://reactome.org/PathwayBrowser/#/R-DME-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Drosophila melanogaster 17865 R-DME-508189 https://reactome.org/PathwayBrowser/#/R-DME-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Drosophila melanogaster 17865 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 17865 R-DME-70723 https://reactome.org/PathwayBrowser/#/R-DME-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Drosophila melanogaster 17865 R-DME-70724 https://reactome.org/PathwayBrowser/#/R-DME-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Drosophila melanogaster 17865 R-DRE-508179 https://reactome.org/PathwayBrowser/#/R-DRE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Danio rerio 17865 R-DRE-508189 https://reactome.org/PathwayBrowser/#/R-DRE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Danio rerio 17865 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 17865 R-DRE-70723 https://reactome.org/PathwayBrowser/#/R-DRE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Danio rerio 17865 R-DRE-70724 https://reactome.org/PathwayBrowser/#/R-DRE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Danio rerio 17865 R-GGA-508189 https://reactome.org/PathwayBrowser/#/R-GGA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Gallus gallus 17865 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 17865 R-GGA-70723 https://reactome.org/PathwayBrowser/#/R-GGA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Gallus gallus 17865 R-HSA-508179 https://reactome.org/PathwayBrowser/#/R-HSA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] TAS Homo sapiens 17865 R-HSA-508189 https://reactome.org/PathwayBrowser/#/R-HSA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] TAS Homo sapiens 17865 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 17865 R-HSA-70723 https://reactome.org/PathwayBrowser/#/R-HSA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] TAS Homo sapiens 17865 R-HSA-70724 https://reactome.org/PathwayBrowser/#/R-HSA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] TAS Homo sapiens 17865 R-MMU-508179 https://reactome.org/PathwayBrowser/#/R-MMU-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Mus musculus 17865 R-MMU-508189 https://reactome.org/PathwayBrowser/#/R-MMU-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Mus musculus 17865 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 17865 R-MMU-70723 https://reactome.org/PathwayBrowser/#/R-MMU-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Mus musculus 17865 R-MMU-70724 https://reactome.org/PathwayBrowser/#/R-MMU-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Mus musculus 17865 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 17865 R-RNO-508179 https://reactome.org/PathwayBrowser/#/R-RNO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Rattus norvegicus 17865 R-RNO-508189 https://reactome.org/PathwayBrowser/#/R-RNO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Rattus norvegicus 17865 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 17865 R-RNO-70723 https://reactome.org/PathwayBrowser/#/R-RNO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Rattus norvegicus 17865 R-RNO-70724 https://reactome.org/PathwayBrowser/#/R-RNO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Rattus norvegicus 17865 R-SCE-508179 https://reactome.org/PathwayBrowser/#/R-SCE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Saccharomyces cerevisiae 17865 R-SCE-508189 https://reactome.org/PathwayBrowser/#/R-SCE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Saccharomyces cerevisiae 17865 R-SCE-70723 https://reactome.org/PathwayBrowser/#/R-SCE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Saccharomyces cerevisiae 17865 R-SCE-70724 https://reactome.org/PathwayBrowser/#/R-SCE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Saccharomyces cerevisiae 17865 R-SPO-508179 https://reactome.org/PathwayBrowser/#/R-SPO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Schizosaccharomyces pombe 17865 R-SPO-508189 https://reactome.org/PathwayBrowser/#/R-SPO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Schizosaccharomyces pombe 17865 R-SPO-70723 https://reactome.org/PathwayBrowser/#/R-SPO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Schizosaccharomyces pombe 17865 R-SPO-70724 https://reactome.org/PathwayBrowser/#/R-SPO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Schizosaccharomyces pombe 17865 R-SSC-508179 https://reactome.org/PathwayBrowser/#/R-SSC-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Sus scrofa 17865 R-SSC-508189 https://reactome.org/PathwayBrowser/#/R-SSC-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Sus scrofa 17865 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 17865 R-SSC-70723 https://reactome.org/PathwayBrowser/#/R-SSC-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Sus scrofa 17865 R-SSC-70724 https://reactome.org/PathwayBrowser/#/R-SSC-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Sus scrofa 17865 R-XTR-508179 https://reactome.org/PathwayBrowser/#/R-XTR-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Xenopus tropicalis 17865 R-XTR-508189 https://reactome.org/PathwayBrowser/#/R-XTR-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Xenopus tropicalis 17865 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 17865 R-XTR-70723 https://reactome.org/PathwayBrowser/#/R-XTR-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Xenopus tropicalis 17865 R-XTR-70724 https://reactome.org/PathwayBrowser/#/R-XTR-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Xenopus tropicalis 17879 R-BTA-2162192 https://reactome.org/PathwayBrowser/#/R-BTA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Bos taurus 17879 R-CEL-2162192 https://reactome.org/PathwayBrowser/#/R-CEL-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Caenorhabditis elegans 17879 R-CFA-2162192 https://reactome.org/PathwayBrowser/#/R-CFA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Canis familiaris 17879 R-DDI-2162192 https://reactome.org/PathwayBrowser/#/R-DDI-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Dictyostelium discoideum 17879 R-DME-2162192 https://reactome.org/PathwayBrowser/#/R-DME-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Drosophila melanogaster 17879 R-DRE-2162192 https://reactome.org/PathwayBrowser/#/R-DRE-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Danio rerio 17879 R-GGA-2162192 https://reactome.org/PathwayBrowser/#/R-GGA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Gallus gallus 17879 R-HSA-2162192 https://reactome.org/PathwayBrowser/#/R-HSA-2162192 COQ2 ligates all-E-10PrP2 to PHB TAS Homo sapiens 17879 R-MMU-2162192 https://reactome.org/PathwayBrowser/#/R-MMU-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Mus musculus 17879 R-PFA-2162192 https://reactome.org/PathwayBrowser/#/R-PFA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Plasmodium falciparum 17879 R-RNO-2162192 https://reactome.org/PathwayBrowser/#/R-RNO-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Rattus norvegicus 17879 R-SCE-2162192 https://reactome.org/PathwayBrowser/#/R-SCE-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Saccharomyces cerevisiae 17879 R-SPO-2162192 https://reactome.org/PathwayBrowser/#/R-SPO-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Schizosaccharomyces pombe 17879 R-SSC-2162192 https://reactome.org/PathwayBrowser/#/R-SSC-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Sus scrofa 17879 R-XTR-2162192 https://reactome.org/PathwayBrowser/#/R-XTR-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Xenopus tropicalis 17883 R-BTA-3301943 https://reactome.org/PathwayBrowser/#/R-BTA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Bos taurus 17883 R-CEL-3301943 https://reactome.org/PathwayBrowser/#/R-CEL-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Caenorhabditis elegans 17883 R-CFA-3301943 https://reactome.org/PathwayBrowser/#/R-CFA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Canis familiaris 17883 R-DRE-3301943 https://reactome.org/PathwayBrowser/#/R-DRE-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Danio rerio 17883 R-GGA-3301943 https://reactome.org/PathwayBrowser/#/R-GGA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Gallus gallus 17883 R-HSA-3301943 https://reactome.org/PathwayBrowser/#/R-HSA-3301943 GSTK1 dimer transfers GS from GSH to CDNB TAS Homo sapiens 17883 R-MMU-3301943 https://reactome.org/PathwayBrowser/#/R-MMU-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Mus musculus 17883 R-RNO-3301943 https://reactome.org/PathwayBrowser/#/R-RNO-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Rattus norvegicus 17883 R-SSC-3301943 https://reactome.org/PathwayBrowser/#/R-SSC-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Sus scrofa 17898 R-BTA-1467466 https://reactome.org/PathwayBrowser/#/R-BTA-1467466 ABCA4 mediates atRAL transport IEA Bos taurus 17898 R-BTA-2399913 https://reactome.org/PathwayBrowser/#/R-BTA-2399913 atRAL binds to RBP2 IEA Bos taurus 17898 R-BTA-2464776 https://reactome.org/PathwayBrowser/#/R-BTA-2464776 Rdh8 reduces atRAL to atROL TAS Bos taurus 17898 R-BTA-2464822 https://reactome.org/PathwayBrowser/#/R-BTA-2464822 RDH12 reduces atRAL to atROL IEA Bos taurus 17898 R-BTA-2465940 https://reactome.org/PathwayBrowser/#/R-BTA-2465940 atRAL is reduced to atROL IEA Bos taurus 17898 R-BTA-2466085 https://reactome.org/PathwayBrowser/#/R-BTA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Bos taurus 17898 R-BTA-2530504 https://reactome.org/PathwayBrowser/#/R-BTA-2530504 MII catalyses GDP/GTP exchange on Gt TAS Bos taurus 17898 R-BTA-2581495 https://reactome.org/PathwayBrowser/#/R-BTA-2581495 Sag binds p-MII to form p-MII:Sag TAS Bos taurus 17898 R-BTA-2632521 https://reactome.org/PathwayBrowser/#/R-BTA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Bos taurus 17898 R-BTA-2855252 https://reactome.org/PathwayBrowser/#/R-BTA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Bos taurus 17898 R-BTA-5362518 https://reactome.org/PathwayBrowser/#/R-BTA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Bos taurus 17898 R-BTA-5362522 https://reactome.org/PathwayBrowser/#/R-BTA-5362522 ALDHs oxidise atRAL to atRA IEA Bos taurus 17898 R-BTA-5362564 https://reactome.org/PathwayBrowser/#/R-BTA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Bos taurus 17898 R-BTA-5419165 https://reactome.org/PathwayBrowser/#/R-BTA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Bos taurus 17898 R-BTA-5615668 https://reactome.org/PathwayBrowser/#/R-BTA-5615668 AKR1C3 reduces atRAL to atROL IEA Bos taurus 17898 R-BTA-5623643 https://reactome.org/PathwayBrowser/#/R-BTA-5623643 RDH13 reduces atRAL to atROL IEA Bos taurus 17898 R-BTA-74831 https://reactome.org/PathwayBrowser/#/R-BTA-74831 p-MII:Sag dissociates to p-Rho and Sag TAS Bos taurus 17898 R-BTA-975629 https://reactome.org/PathwayBrowser/#/R-BTA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Bos taurus 17898 R-BTA-975635 https://reactome.org/PathwayBrowser/#/R-BTA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Bos taurus 17898 R-CEL-1467466 https://reactome.org/PathwayBrowser/#/R-CEL-1467466 ABCA4 mediates atRAL transport IEA Caenorhabditis elegans 17898 R-CEL-2399913 https://reactome.org/PathwayBrowser/#/R-CEL-2399913 atRAL binds to RBP2 IEA Caenorhabditis elegans 17898 R-CEL-2465940 https://reactome.org/PathwayBrowser/#/R-CEL-2465940 atRAL is reduced to atROL IEA Caenorhabditis elegans 17898 R-CEL-2466085 https://reactome.org/PathwayBrowser/#/R-CEL-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Caenorhabditis elegans 17898 R-CEL-2632521 https://reactome.org/PathwayBrowser/#/R-CEL-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Caenorhabditis elegans 17898 R-CEL-2855252 https://reactome.org/PathwayBrowser/#/R-CEL-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Caenorhabditis elegans 17898 R-CEL-5362518 https://reactome.org/PathwayBrowser/#/R-CEL-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Caenorhabditis elegans 17898 R-CEL-5362522 https://reactome.org/PathwayBrowser/#/R-CEL-5362522 ALDHs oxidise atRAL to atRA IEA Caenorhabditis elegans 17898 R-CEL-5362564 https://reactome.org/PathwayBrowser/#/R-CEL-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Caenorhabditis elegans 17898 R-CEL-5419165 https://reactome.org/PathwayBrowser/#/R-CEL-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Caenorhabditis elegans 17898 R-CEL-5615668 https://reactome.org/PathwayBrowser/#/R-CEL-5615668 AKR1C3 reduces atRAL to atROL IEA Caenorhabditis elegans 17898 R-CEL-5623643 https://reactome.org/PathwayBrowser/#/R-CEL-5623643 RDH13 reduces atRAL to atROL IEA Caenorhabditis elegans 17898 R-CEL-975635 https://reactome.org/PathwayBrowser/#/R-CEL-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Caenorhabditis elegans 17898 R-CFA-1467466 https://reactome.org/PathwayBrowser/#/R-CFA-1467466 ABCA4 mediates atRAL transport IEA Canis familiaris 17898 R-CFA-2399913 https://reactome.org/PathwayBrowser/#/R-CFA-2399913 atRAL binds to RBP2 IEA Canis familiaris 17898 R-CFA-2464822 https://reactome.org/PathwayBrowser/#/R-CFA-2464822 RDH12 reduces atRAL to atROL IEA Canis familiaris 17898 R-CFA-2465940 https://reactome.org/PathwayBrowser/#/R-CFA-2465940 atRAL is reduced to atROL IEA Canis familiaris 17898 R-CFA-2466085 https://reactome.org/PathwayBrowser/#/R-CFA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Canis familiaris 17898 R-CFA-2632521 https://reactome.org/PathwayBrowser/#/R-CFA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Canis familiaris 17898 R-CFA-5362518 https://reactome.org/PathwayBrowser/#/R-CFA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Canis familiaris 17898 R-CFA-5362522 https://reactome.org/PathwayBrowser/#/R-CFA-5362522 ALDHs oxidise atRAL to atRA IEA Canis familiaris 17898 R-CFA-5362564 https://reactome.org/PathwayBrowser/#/R-CFA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Canis familiaris 17898 R-CFA-5419165 https://reactome.org/PathwayBrowser/#/R-CFA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Canis familiaris 17898 R-CFA-5623643 https://reactome.org/PathwayBrowser/#/R-CFA-5623643 RDH13 reduces atRAL to atROL IEA Canis familiaris 17898 R-CFA-975635 https://reactome.org/PathwayBrowser/#/R-CFA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Canis familiaris 17898 R-DDI-1467466 https://reactome.org/PathwayBrowser/#/R-DDI-1467466 ABCA4 mediates atRAL transport IEA Dictyostelium discoideum 17898 R-DDI-5362522 https://reactome.org/PathwayBrowser/#/R-DDI-5362522 ALDHs oxidise atRAL to atRA IEA Dictyostelium discoideum 17898 R-DDI-5362564 https://reactome.org/PathwayBrowser/#/R-DDI-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Dictyostelium discoideum 17898 R-DDI-5419165 https://reactome.org/PathwayBrowser/#/R-DDI-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Dictyostelium discoideum 17898 R-DDI-5615668 https://reactome.org/PathwayBrowser/#/R-DDI-5615668 AKR1C3 reduces atRAL to atROL IEA Dictyostelium discoideum 17898 R-DDI-5623643 https://reactome.org/PathwayBrowser/#/R-DDI-5623643 RDH13 reduces atRAL to atROL IEA Dictyostelium discoideum 17898 R-DME-1467466 https://reactome.org/PathwayBrowser/#/R-DME-1467466 ABCA4 mediates atRAL transport IEA Drosophila melanogaster 17898 R-DME-2399913 https://reactome.org/PathwayBrowser/#/R-DME-2399913 atRAL binds to RBP2 IEA Drosophila melanogaster 17898 R-DME-2464822 https://reactome.org/PathwayBrowser/#/R-DME-2464822 RDH12 reduces atRAL to atROL IEA Drosophila melanogaster 17898 R-DME-2465940 https://reactome.org/PathwayBrowser/#/R-DME-2465940 atRAL is reduced to atROL IEA Drosophila melanogaster 17898 R-DME-2855252 https://reactome.org/PathwayBrowser/#/R-DME-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 17898 R-DME-5362518 https://reactome.org/PathwayBrowser/#/R-DME-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Drosophila melanogaster 17898 R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster 17898 R-DME-5362564 https://reactome.org/PathwayBrowser/#/R-DME-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Drosophila melanogaster 17898 R-DME-5419165 https://reactome.org/PathwayBrowser/#/R-DME-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Drosophila melanogaster 17898 R-DME-5615668 https://reactome.org/PathwayBrowser/#/R-DME-5615668 AKR1C3 reduces atRAL to atROL IEA Drosophila melanogaster 17898 R-DME-975629 https://reactome.org/PathwayBrowser/#/R-DME-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 17898 R-DME-975635 https://reactome.org/PathwayBrowser/#/R-DME-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Drosophila melanogaster 17898 R-DRE-2399913 https://reactome.org/PathwayBrowser/#/R-DRE-2399913 atRAL binds to RBP2 IEA Danio rerio 17898 R-DRE-2464822 https://reactome.org/PathwayBrowser/#/R-DRE-2464822 RDH12 reduces atRAL to atROL IEA Danio rerio 17898 R-DRE-2465940 https://reactome.org/PathwayBrowser/#/R-DRE-2465940 atRAL is reduced to atROL IEA Danio rerio 17898 R-DRE-2466085 https://reactome.org/PathwayBrowser/#/R-DRE-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Danio rerio 17898 R-DRE-2632521 https://reactome.org/PathwayBrowser/#/R-DRE-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Danio rerio 17898 R-DRE-2855252 https://reactome.org/PathwayBrowser/#/R-DRE-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Danio rerio 17898 R-DRE-5362518 https://reactome.org/PathwayBrowser/#/R-DRE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Danio rerio 17898 R-DRE-5362522 https://reactome.org/PathwayBrowser/#/R-DRE-5362522 ALDHs oxidise atRAL to atRA IEA Danio rerio 17898 R-DRE-5362564 https://reactome.org/PathwayBrowser/#/R-DRE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Danio rerio 17898 R-DRE-5419165 https://reactome.org/PathwayBrowser/#/R-DRE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Danio rerio 17898 R-DRE-975629 https://reactome.org/PathwayBrowser/#/R-DRE-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Danio rerio 17898 R-DRE-975635 https://reactome.org/PathwayBrowser/#/R-DRE-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Danio rerio 17898 R-GGA-1467466 https://reactome.org/PathwayBrowser/#/R-GGA-1467466 ABCA4 mediates atRAL transport IEA Gallus gallus 17898 R-GGA-2399913 https://reactome.org/PathwayBrowser/#/R-GGA-2399913 atRAL binds to RBP2 IEA Gallus gallus 17898 R-GGA-2464822 https://reactome.org/PathwayBrowser/#/R-GGA-2464822 RDH12 reduces atRAL to atROL IEA Gallus gallus 17898 R-GGA-2465940 https://reactome.org/PathwayBrowser/#/R-GGA-2465940 atRAL is reduced to atROL IEA Gallus gallus 17898 R-GGA-2466085 https://reactome.org/PathwayBrowser/#/R-GGA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Gallus gallus 17898 R-GGA-2632521 https://reactome.org/PathwayBrowser/#/R-GGA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Gallus gallus 17898 R-GGA-2855252 https://reactome.org/PathwayBrowser/#/R-GGA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Gallus gallus 17898 R-GGA-5362518 https://reactome.org/PathwayBrowser/#/R-GGA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Gallus gallus 17898 R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus 17898 R-GGA-5362564 https://reactome.org/PathwayBrowser/#/R-GGA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Gallus gallus 17898 R-GGA-5419165 https://reactome.org/PathwayBrowser/#/R-GGA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Gallus gallus 17898 R-GGA-975629 https://reactome.org/PathwayBrowser/#/R-GGA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Gallus gallus 17898 R-GGA-975635 https://reactome.org/PathwayBrowser/#/R-GGA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Gallus gallus 17898 R-HSA-1467466 https://reactome.org/PathwayBrowser/#/R-HSA-1467466 ABCA4 mediates atRAL transport TAS Homo sapiens 17898 R-HSA-2399913 https://reactome.org/PathwayBrowser/#/R-HSA-2399913 atRAL binds to RBP2 TAS Homo sapiens 17898 R-HSA-2464803 https://reactome.org/PathwayBrowser/#/R-HSA-2464803 RDH8 reduces atRAL to atROL IEA Homo sapiens 17898 R-HSA-2464810 https://reactome.org/PathwayBrowser/#/R-HSA-2464810 atRAL(membrane) diffuses to atRAL(cytosol) TAS Homo sapiens 17898 R-HSA-2464822 https://reactome.org/PathwayBrowser/#/R-HSA-2464822 RDH12 reduces atRAL to atROL TAS Homo sapiens 17898 R-HSA-2465940 https://reactome.org/PathwayBrowser/#/R-HSA-2465940 atRAL is reduced to atROL TAS Homo sapiens 17898 R-HSA-2466085 https://reactome.org/PathwayBrowser/#/R-HSA-2466085 at-retinyl is hydrolysed from R* to release atRAL TAS Homo sapiens 17898 R-HSA-2466718 https://reactome.org/PathwayBrowser/#/R-HSA-2466718 NRPE dissociates to atRAL and PE TAS Homo sapiens 17898 R-HSA-2466764 https://reactome.org/PathwayBrowser/#/R-HSA-2466764 NRPE condenses with atRAL to form A2PE TAS Homo sapiens 17898 R-HSA-2466846 https://reactome.org/PathwayBrowser/#/R-HSA-2466846 atRAL can spontaneously react with PE to form NRPE TAS Homo sapiens 17898 R-HSA-2466861 https://reactome.org/PathwayBrowser/#/R-HSA-2466861 Defective RDH12 does not reduce atRAL to atROL and causes LCA13 TAS Homo sapiens 17898 R-HSA-2471670 https://reactome.org/PathwayBrowser/#/R-HSA-2471670 Defective RDH12 does not reduce atRAL to atROL TAS Homo sapiens 17898 R-HSA-2632521 https://reactome.org/PathwayBrowser/#/R-HSA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL TAS Homo sapiens 17898 R-HSA-2855252 https://reactome.org/PathwayBrowser/#/R-HSA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL TAS Homo sapiens 17898 R-HSA-5362518 https://reactome.org/PathwayBrowser/#/R-HSA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL TAS Homo sapiens 17898 R-HSA-5362522 https://reactome.org/PathwayBrowser/#/R-HSA-5362522 ALDHs oxidise atRAL to atRA TAS Homo sapiens 17898 R-HSA-5362564 https://reactome.org/PathwayBrowser/#/R-HSA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro TAS Homo sapiens 17898 R-HSA-5419165 https://reactome.org/PathwayBrowser/#/R-HSA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL TAS Homo sapiens 17898 R-HSA-5615668 https://reactome.org/PathwayBrowser/#/R-HSA-5615668 AKR1C3 reduces atRAL to atROL TAS Homo sapiens 17898 R-HSA-5623643 https://reactome.org/PathwayBrowser/#/R-HSA-5623643 RDH13 reduces atRAL to atROL TAS Homo sapiens 17898 R-HSA-975629 https://reactome.org/PathwayBrowser/#/R-HSA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL TAS Homo sapiens 17898 R-HSA-975635 https://reactome.org/PathwayBrowser/#/R-HSA-975635 BCMO1:Fe2+ cleaves betaC to atRAL TAS Homo sapiens 17898 R-MMU-1467466 https://reactome.org/PathwayBrowser/#/R-MMU-1467466 ABCA4 mediates atRAL transport IEA Mus musculus 17898 R-MMU-2399913 https://reactome.org/PathwayBrowser/#/R-MMU-2399913 atRAL binds to RBP2 IEA Mus musculus 17898 R-MMU-2464822 https://reactome.org/PathwayBrowser/#/R-MMU-2464822 RDH12 reduces atRAL to atROL IEA Mus musculus 17898 R-MMU-2465940 https://reactome.org/PathwayBrowser/#/R-MMU-2465940 atRAL is reduced to atROL IEA Mus musculus 17898 R-MMU-2466085 https://reactome.org/PathwayBrowser/#/R-MMU-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Mus musculus 17898 R-MMU-2632521 https://reactome.org/PathwayBrowser/#/R-MMU-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Mus musculus 17898 R-MMU-2855252 https://reactome.org/PathwayBrowser/#/R-MMU-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Mus musculus 17898 R-MMU-5362518 https://reactome.org/PathwayBrowser/#/R-MMU-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Mus musculus 17898 R-MMU-5362522 https://reactome.org/PathwayBrowser/#/R-MMU-5362522 ALDHs oxidise atRAL to atRA IEA Mus musculus 17898 R-MMU-5362564 https://reactome.org/PathwayBrowser/#/R-MMU-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Mus musculus 17898 R-MMU-5419165 https://reactome.org/PathwayBrowser/#/R-MMU-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Mus musculus 17898 R-MMU-5615668 https://reactome.org/PathwayBrowser/#/R-MMU-5615668 AKR1C3 reduces atRAL to atROL IEA Mus musculus 17898 R-MMU-5623643 https://reactome.org/PathwayBrowser/#/R-MMU-5623643 RDH13 reduces atRAL to atROL IEA Mus musculus 17898 R-MMU-975629 https://reactome.org/PathwayBrowser/#/R-MMU-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Mus musculus 17898 R-MMU-975635 https://reactome.org/PathwayBrowser/#/R-MMU-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Mus musculus 17898 R-PFA-1467466 https://reactome.org/PathwayBrowser/#/R-PFA-1467466 ABCA4 mediates atRAL transport IEA Plasmodium falciparum 17898 R-PFA-5623643 https://reactome.org/PathwayBrowser/#/R-PFA-5623643 RDH13 reduces atRAL to atROL IEA Plasmodium falciparum 17898 R-RNO-2399913 https://reactome.org/PathwayBrowser/#/R-RNO-2399913 atRAL binds to RBP2 IEA Rattus norvegicus 17898 R-RNO-2464822 https://reactome.org/PathwayBrowser/#/R-RNO-2464822 RDH12 reduces atRAL to atROL IEA Rattus norvegicus 17898 R-RNO-2465940 https://reactome.org/PathwayBrowser/#/R-RNO-2465940 atRAL is reduced to atROL IEA Rattus norvegicus 17898 R-RNO-2466085 https://reactome.org/PathwayBrowser/#/R-RNO-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Rattus norvegicus 17898 R-RNO-2632521 https://reactome.org/PathwayBrowser/#/R-RNO-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Rattus norvegicus 17898 R-RNO-2855252 https://reactome.org/PathwayBrowser/#/R-RNO-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 17898 R-RNO-5362518 https://reactome.org/PathwayBrowser/#/R-RNO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Rattus norvegicus 17898 R-RNO-5362522 https://reactome.org/PathwayBrowser/#/R-RNO-5362522 ALDHs oxidise atRAL to atRA IEA Rattus norvegicus 17898 R-RNO-5362564 https://reactome.org/PathwayBrowser/#/R-RNO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Rattus norvegicus 17898 R-RNO-5419165 https://reactome.org/PathwayBrowser/#/R-RNO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Rattus norvegicus 17898 R-RNO-5615668 https://reactome.org/PathwayBrowser/#/R-RNO-5615668 AKR1C3 reduces atRAL to atROL IEA Rattus norvegicus 17898 R-RNO-5623643 https://reactome.org/PathwayBrowser/#/R-RNO-5623643 RDH13 reduces atRAL to atROL IEA Rattus norvegicus 17898 R-RNO-975629 https://reactome.org/PathwayBrowser/#/R-RNO-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 17898 R-RNO-975635 https://reactome.org/PathwayBrowser/#/R-RNO-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Rattus norvegicus 17898 R-SCE-2465940 https://reactome.org/PathwayBrowser/#/R-SCE-2465940 atRAL is reduced to atROL IEA Saccharomyces cerevisiae 17898 R-SCE-5362518 https://reactome.org/PathwayBrowser/#/R-SCE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Saccharomyces cerevisiae 17898 R-SCE-5362522 https://reactome.org/PathwayBrowser/#/R-SCE-5362522 ALDHs oxidise atRAL to atRA IEA Saccharomyces cerevisiae 17898 R-SCE-5362564 https://reactome.org/PathwayBrowser/#/R-SCE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Saccharomyces cerevisiae 17898 R-SCE-5419165 https://reactome.org/PathwayBrowser/#/R-SCE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Saccharomyces cerevisiae 17898 R-SCE-5615668 https://reactome.org/PathwayBrowser/#/R-SCE-5615668 AKR1C3 reduces atRAL to atROL IEA Saccharomyces cerevisiae 17898 R-SPO-5362518 https://reactome.org/PathwayBrowser/#/R-SPO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Schizosaccharomyces pombe 17898 R-SPO-5362522 https://reactome.org/PathwayBrowser/#/R-SPO-5362522 ALDHs oxidise atRAL to atRA IEA Schizosaccharomyces pombe 17898 R-SPO-5362564 https://reactome.org/PathwayBrowser/#/R-SPO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Schizosaccharomyces pombe 17898 R-SPO-5419165 https://reactome.org/PathwayBrowser/#/R-SPO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Schizosaccharomyces pombe 17898 R-SPO-5615668 https://reactome.org/PathwayBrowser/#/R-SPO-5615668 AKR1C3 reduces atRAL to atROL IEA Schizosaccharomyces pombe 17898 R-SSC-1467466 https://reactome.org/PathwayBrowser/#/R-SSC-1467466 ABCA4 mediates atRAL transport IEA Sus scrofa 17898 R-SSC-2399913 https://reactome.org/PathwayBrowser/#/R-SSC-2399913 atRAL binds to RBP2 IEA Sus scrofa 17898 R-SSC-2464822 https://reactome.org/PathwayBrowser/#/R-SSC-2464822 RDH12 reduces atRAL to atROL IEA Sus scrofa 17898 R-SSC-2465940 https://reactome.org/PathwayBrowser/#/R-SSC-2465940 atRAL is reduced to atROL IEA Sus scrofa 17898 R-SSC-2466085 https://reactome.org/PathwayBrowser/#/R-SSC-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Sus scrofa 17898 R-SSC-2632521 https://reactome.org/PathwayBrowser/#/R-SSC-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Sus scrofa 17898 R-SSC-2855252 https://reactome.org/PathwayBrowser/#/R-SSC-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Sus scrofa 17898 R-SSC-5362518 https://reactome.org/PathwayBrowser/#/R-SSC-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Sus scrofa 17898 R-SSC-5362522 https://reactome.org/PathwayBrowser/#/R-SSC-5362522 ALDHs oxidise atRAL to atRA IEA Sus scrofa 17898 R-SSC-5362564 https://reactome.org/PathwayBrowser/#/R-SSC-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Sus scrofa 17898 R-SSC-5419165 https://reactome.org/PathwayBrowser/#/R-SSC-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Sus scrofa 17898 R-SSC-5615668 https://reactome.org/PathwayBrowser/#/R-SSC-5615668 AKR1C3 reduces atRAL to atROL IEA Sus scrofa 17898 R-SSC-5623643 https://reactome.org/PathwayBrowser/#/R-SSC-5623643 RDH13 reduces atRAL to atROL IEA Sus scrofa 17898 R-SSC-975629 https://reactome.org/PathwayBrowser/#/R-SSC-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Sus scrofa 17898 R-SSC-975635 https://reactome.org/PathwayBrowser/#/R-SSC-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Sus scrofa 17898 R-XTR-1467466 https://reactome.org/PathwayBrowser/#/R-XTR-1467466 ABCA4 mediates atRAL transport IEA Xenopus tropicalis 17898 R-XTR-2399913 https://reactome.org/PathwayBrowser/#/R-XTR-2399913 atRAL binds to RBP2 IEA Xenopus tropicalis 17898 R-XTR-2465940 https://reactome.org/PathwayBrowser/#/R-XTR-2465940 atRAL is reduced to atROL IEA Xenopus tropicalis 17898 R-XTR-2466085 https://reactome.org/PathwayBrowser/#/R-XTR-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Xenopus tropicalis 17898 R-XTR-2855252 https://reactome.org/PathwayBrowser/#/R-XTR-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Xenopus tropicalis 17898 R-XTR-5362518 https://reactome.org/PathwayBrowser/#/R-XTR-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Xenopus tropicalis 17898 R-XTR-5362522 https://reactome.org/PathwayBrowser/#/R-XTR-5362522 ALDHs oxidise atRAL to atRA IEA Xenopus tropicalis 17898 R-XTR-5362564 https://reactome.org/PathwayBrowser/#/R-XTR-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Xenopus tropicalis 17898 R-XTR-5419165 https://reactome.org/PathwayBrowser/#/R-XTR-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Xenopus tropicalis 17898 R-XTR-5615668 https://reactome.org/PathwayBrowser/#/R-XTR-5615668 AKR1C3 reduces atRAL to atROL IEA Xenopus tropicalis 17898 R-XTR-5623643 https://reactome.org/PathwayBrowser/#/R-XTR-5623643 RDH13 reduces atRAL to atROL IEA Xenopus tropicalis 17898 R-XTR-975635 https://reactome.org/PathwayBrowser/#/R-XTR-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Xenopus tropicalis 17899 R-BTA-192033 https://reactome.org/PathwayBrowser/#/R-BTA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Bos taurus 17899 R-BTA-192097 https://reactome.org/PathwayBrowser/#/R-BTA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Bos taurus 17899 R-CEL-192033 https://reactome.org/PathwayBrowser/#/R-CEL-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Caenorhabditis elegans 17899 R-CFA-192033 https://reactome.org/PathwayBrowser/#/R-CFA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Canis familiaris 17899 R-CFA-192097 https://reactome.org/PathwayBrowser/#/R-CFA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Canis familiaris 17899 R-CFA-192157 https://reactome.org/PathwayBrowser/#/R-CFA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Canis familiaris 17899 R-DDI-192033 https://reactome.org/PathwayBrowser/#/R-DDI-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Dictyostelium discoideum 17899 R-DME-192033 https://reactome.org/PathwayBrowser/#/R-DME-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Drosophila melanogaster 17899 R-DRE-192097 https://reactome.org/PathwayBrowser/#/R-DRE-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Danio rerio 17899 R-DRE-192157 https://reactome.org/PathwayBrowser/#/R-DRE-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Danio rerio 17899 R-GGA-192033 https://reactome.org/PathwayBrowser/#/R-GGA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Gallus gallus 17899 R-HSA-192033 https://reactome.org/PathwayBrowser/#/R-HSA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one TAS Homo sapiens 17899 R-HSA-192097 https://reactome.org/PathwayBrowser/#/R-HSA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one TAS Homo sapiens 17899 R-HSA-192157 https://reactome.org/PathwayBrowser/#/R-HSA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE TAS Homo sapiens 17899 R-MMU-192033 https://reactome.org/PathwayBrowser/#/R-MMU-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Mus musculus 17899 R-MMU-192097 https://reactome.org/PathwayBrowser/#/R-MMU-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Mus musculus 17899 R-MMU-192157 https://reactome.org/PathwayBrowser/#/R-MMU-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Mus musculus 17899 R-RNO-192033 https://reactome.org/PathwayBrowser/#/R-RNO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Rattus norvegicus 17899 R-RNO-192097 https://reactome.org/PathwayBrowser/#/R-RNO-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Rattus norvegicus 17899 R-RNO-192157 https://reactome.org/PathwayBrowser/#/R-RNO-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Rattus norvegicus 17899 R-SCE-192033 https://reactome.org/PathwayBrowser/#/R-SCE-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Saccharomyces cerevisiae 17899 R-SPO-192033 https://reactome.org/PathwayBrowser/#/R-SPO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Schizosaccharomyces pombe 17899 R-SSC-192033 https://reactome.org/PathwayBrowser/#/R-SSC-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Sus scrofa 17899 R-SSC-192097 https://reactome.org/PathwayBrowser/#/R-SSC-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Sus scrofa 17899 R-SSC-192157 https://reactome.org/PathwayBrowser/#/R-SSC-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Sus scrofa 17899 R-XTR-192033 https://reactome.org/PathwayBrowser/#/R-XTR-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Xenopus tropicalis 17899 R-XTR-192097 https://reactome.org/PathwayBrowser/#/R-XTR-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Xenopus tropicalis 17899 R-XTR-192157 https://reactome.org/PathwayBrowser/#/R-XTR-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Xenopus tropicalis 17909 R-BTA-111285 https://reactome.org/PathwayBrowser/#/R-BTA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Bos taurus 17909 R-BTA-111289 https://reactome.org/PathwayBrowser/#/R-BTA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Bos taurus 17909 R-BTA-73815 https://reactome.org/PathwayBrowser/#/R-BTA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Bos taurus 17909 R-CEL-111285 https://reactome.org/PathwayBrowser/#/R-CEL-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Caenorhabditis elegans 17909 R-CEL-111289 https://reactome.org/PathwayBrowser/#/R-CEL-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Caenorhabditis elegans 17909 R-CEL-73815 https://reactome.org/PathwayBrowser/#/R-CEL-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Caenorhabditis elegans 17909 R-CFA-111285 https://reactome.org/PathwayBrowser/#/R-CFA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Canis familiaris 17909 R-CFA-111289 https://reactome.org/PathwayBrowser/#/R-CFA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Canis familiaris 17909 R-CFA-73815 https://reactome.org/PathwayBrowser/#/R-CFA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Canis familiaris 17909 R-DME-111285 https://reactome.org/PathwayBrowser/#/R-DME-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Drosophila melanogaster 17909 R-DME-111289 https://reactome.org/PathwayBrowser/#/R-DME-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Drosophila melanogaster 17909 R-DME-73815 https://reactome.org/PathwayBrowser/#/R-DME-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Drosophila melanogaster 17909 R-DRE-111285 https://reactome.org/PathwayBrowser/#/R-DRE-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Danio rerio 17909 R-DRE-111289 https://reactome.org/PathwayBrowser/#/R-DRE-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Danio rerio 17909 R-DRE-73815 https://reactome.org/PathwayBrowser/#/R-DRE-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Danio rerio 17909 R-GGA-111285 https://reactome.org/PathwayBrowser/#/R-GGA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Gallus gallus 17909 R-GGA-111289 https://reactome.org/PathwayBrowser/#/R-GGA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Gallus gallus 17909 R-GGA-73815 https://reactome.org/PathwayBrowser/#/R-GGA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Gallus gallus 17909 R-HSA-111285 https://reactome.org/PathwayBrowser/#/R-HSA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer TAS Homo sapiens 17909 R-HSA-111289 https://reactome.org/PathwayBrowser/#/R-HSA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer TAS Homo sapiens 17909 R-HSA-73815 https://reactome.org/PathwayBrowser/#/R-HSA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate TAS Homo sapiens 17909 R-MMU-111285 https://reactome.org/PathwayBrowser/#/R-MMU-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Mus musculus 17909 R-MMU-111289 https://reactome.org/PathwayBrowser/#/R-MMU-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Mus musculus 17909 R-MMU-73815 https://reactome.org/PathwayBrowser/#/R-MMU-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Mus musculus 17909 R-RNO-111285 https://reactome.org/PathwayBrowser/#/R-RNO-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Rattus norvegicus 17909 R-RNO-111289 https://reactome.org/PathwayBrowser/#/R-RNO-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Rattus norvegicus 17909 R-RNO-73815 https://reactome.org/PathwayBrowser/#/R-RNO-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Rattus norvegicus 17909 R-SSC-111285 https://reactome.org/PathwayBrowser/#/R-SSC-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Sus scrofa 17909 R-SSC-111289 https://reactome.org/PathwayBrowser/#/R-SSC-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Sus scrofa 17909 R-SSC-73815 https://reactome.org/PathwayBrowser/#/R-SSC-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Sus scrofa 17909 R-XTR-111285 https://reactome.org/PathwayBrowser/#/R-XTR-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Xenopus tropicalis 17909 R-XTR-111289 https://reactome.org/PathwayBrowser/#/R-XTR-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Xenopus tropicalis 17909 R-XTR-73815 https://reactome.org/PathwayBrowser/#/R-XTR-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Xenopus tropicalis 17924 R-BTA-5652172 https://reactome.org/PathwayBrowser/#/R-BTA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Bos taurus 17924 R-BTA-5652195 https://reactome.org/PathwayBrowser/#/R-BTA-5652195 SORD oxidizes D-sorbitol to Fru IEA Bos taurus 17924 R-CEL-5652172 https://reactome.org/PathwayBrowser/#/R-CEL-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Caenorhabditis elegans 17924 R-CEL-5652195 https://reactome.org/PathwayBrowser/#/R-CEL-5652195 SORD oxidizes D-sorbitol to Fru IEA Caenorhabditis elegans 17924 R-CFA-5652172 https://reactome.org/PathwayBrowser/#/R-CFA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Canis familiaris 17924 R-CFA-5652195 https://reactome.org/PathwayBrowser/#/R-CFA-5652195 SORD oxidizes D-sorbitol to Fru IEA Canis familiaris 17924 R-DDI-5652172 https://reactome.org/PathwayBrowser/#/R-DDI-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Dictyostelium discoideum 17924 R-DME-5652172 https://reactome.org/PathwayBrowser/#/R-DME-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Drosophila melanogaster 17924 R-DME-5652195 https://reactome.org/PathwayBrowser/#/R-DME-5652195 SORD oxidizes D-sorbitol to Fru IEA Drosophila melanogaster 17924 R-DRE-5652172 https://reactome.org/PathwayBrowser/#/R-DRE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Danio rerio 17924 R-GGA-5652172 https://reactome.org/PathwayBrowser/#/R-GGA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Gallus gallus 17924 R-GGA-5652195 https://reactome.org/PathwayBrowser/#/R-GGA-5652195 SORD oxidizes D-sorbitol to Fru IEA Gallus gallus 17924 R-HSA-5652172 https://reactome.org/PathwayBrowser/#/R-HSA-5652172 AKR1B1 reduces Glc to D-sorbitol TAS Homo sapiens 17924 R-HSA-5652195 https://reactome.org/PathwayBrowser/#/R-HSA-5652195 SORD oxidizes D-sorbitol to Fru TAS Homo sapiens 17924 R-MMU-5652172 https://reactome.org/PathwayBrowser/#/R-MMU-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Mus musculus 17924 R-MMU-5652195 https://reactome.org/PathwayBrowser/#/R-MMU-5652195 SORD oxidizes D-sorbitol to Fru IEA Mus musculus 17924 R-RNO-5652172 https://reactome.org/PathwayBrowser/#/R-RNO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Rattus norvegicus 17924 R-RNO-5652195 https://reactome.org/PathwayBrowser/#/R-RNO-5652195 SORD oxidizes D-sorbitol to Fru IEA Rattus norvegicus 17924 R-SCE-5652172 https://reactome.org/PathwayBrowser/#/R-SCE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Saccharomyces cerevisiae 17924 R-SCE-5652195 https://reactome.org/PathwayBrowser/#/R-SCE-5652195 SORD oxidizes D-sorbitol to Fru IEA Saccharomyces cerevisiae 17924 R-SPO-5652172 https://reactome.org/PathwayBrowser/#/R-SPO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Schizosaccharomyces pombe 17924 R-SPO-5652195 https://reactome.org/PathwayBrowser/#/R-SPO-5652195 SORD oxidizes D-sorbitol to Fru IEA Schizosaccharomyces pombe 17924 R-SSC-5652172 https://reactome.org/PathwayBrowser/#/R-SSC-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Sus scrofa 17924 R-SSC-5652195 https://reactome.org/PathwayBrowser/#/R-SSC-5652195 SORD oxidizes D-sorbitol to Fru IEA Sus scrofa 17924 R-XTR-5652172 https://reactome.org/PathwayBrowser/#/R-XTR-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Xenopus tropicalis 17924 R-XTR-5652195 https://reactome.org/PathwayBrowser/#/R-XTR-5652195 SORD oxidizes D-sorbitol to Fru IEA Xenopus tropicalis 17925 R-BTA-1605591 https://reactome.org/PathwayBrowser/#/R-BTA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Bos taurus 17925 R-BTA-1606564 https://reactome.org/PathwayBrowser/#/R-BTA-1606564 GALC hydrolyzes GalCer IEA Bos taurus 17925 R-BTA-1861788 https://reactome.org/PathwayBrowser/#/R-BTA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Bos taurus 17925 R-BTA-1861789 https://reactome.org/PathwayBrowser/#/R-BTA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Bos taurus 17925 R-BTA-188979 https://reactome.org/PathwayBrowser/#/R-BTA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Bos taurus 17925 R-BTA-189053 https://reactome.org/PathwayBrowser/#/R-BTA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Bos taurus 17925 R-BTA-189062 https://reactome.org/PathwayBrowser/#/R-BTA-189062 lactose + H2O => D-glucose + D-galactose IEA Bos taurus 17925 R-BTA-189069 https://reactome.org/PathwayBrowser/#/R-BTA-189069 sucrose + H2O => glucose + fructose IEA Bos taurus 17925 R-BTA-189102 https://reactome.org/PathwayBrowser/#/R-BTA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Bos taurus 17925 R-BTA-189208 https://reactome.org/PathwayBrowser/#/R-BTA-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Bos taurus 17925 R-BTA-189242 https://reactome.org/PathwayBrowser/#/R-BTA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Bos taurus 17925 R-BTA-191101 https://reactome.org/PathwayBrowser/#/R-BTA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Bos taurus 17925 R-BTA-191108 https://reactome.org/PathwayBrowser/#/R-BTA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Bos taurus 17925 R-BTA-191114 https://reactome.org/PathwayBrowser/#/R-BTA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Bos taurus 17925 R-BTA-191116 https://reactome.org/PathwayBrowser/#/R-BTA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Bos taurus 17925 R-BTA-265682 https://reactome.org/PathwayBrowser/#/R-BTA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Bos taurus 17925 R-BTA-3262512 https://reactome.org/PathwayBrowser/#/R-BTA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Bos taurus 17925 R-BTA-3266566 https://reactome.org/PathwayBrowser/#/R-BTA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Bos taurus 17925 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 17925 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 17925 R-BTA-422048 https://reactome.org/PathwayBrowser/#/R-BTA-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Bos taurus 17925 R-BTA-428779 https://reactome.org/PathwayBrowser/#/R-BTA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Bos taurus 17925 R-BTA-429036 https://reactome.org/PathwayBrowser/#/R-BTA-429036 SLC2A9 transports Fru, Glc, urate IEA Bos taurus 17925 R-BTA-429094 https://reactome.org/PathwayBrowser/#/R-BTA-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Bos taurus 17925 R-BTA-429567 https://reactome.org/PathwayBrowser/#/R-BTA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Bos taurus 17925 R-BTA-429613 https://reactome.org/PathwayBrowser/#/R-BTA-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Bos taurus 17925 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 17925 R-BTA-450095 https://reactome.org/PathwayBrowser/#/R-BTA-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Bos taurus 17925 R-BTA-499981 https://reactome.org/PathwayBrowser/#/R-BTA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Bos taurus 17925 R-BTA-5339524 https://reactome.org/PathwayBrowser/#/R-BTA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Bos taurus 17925 R-BTA-5652172 https://reactome.org/PathwayBrowser/#/R-BTA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Bos taurus 17925 R-BTA-5653873 https://reactome.org/PathwayBrowser/#/R-BTA-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Bos taurus 17925 R-BTA-5653878 https://reactome.org/PathwayBrowser/#/R-BTA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Bos taurus 17925 R-BTA-5659861 https://reactome.org/PathwayBrowser/#/R-BTA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Bos taurus 17925 R-BTA-5696021 https://reactome.org/PathwayBrowser/#/R-BTA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Bos taurus 17925 R-BTA-70420 https://reactome.org/PathwayBrowser/#/R-BTA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Bos taurus 17925 R-BTA-71593 https://reactome.org/PathwayBrowser/#/R-BTA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Bos taurus 17925 R-BTA-71825 https://reactome.org/PathwayBrowser/#/R-BTA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Bos taurus 17925 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 17925 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 17925 R-BTA-8875902 https://reactome.org/PathwayBrowser/#/R-BTA-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Bos taurus 17925 R-BTA-8932955 https://reactome.org/PathwayBrowser/#/R-BTA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Bos taurus 17925 R-BTA-8981553 https://reactome.org/PathwayBrowser/#/R-BTA-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Bos taurus 17925 R-BTA-8981564 https://reactome.org/PathwayBrowser/#/R-BTA-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Bos taurus 17925 R-BTA-8981570 https://reactome.org/PathwayBrowser/#/R-BTA-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Bos taurus 17925 R-BTA-8981574 https://reactome.org/PathwayBrowser/#/R-BTA-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Bos taurus 17925 R-BTA-9036727 https://reactome.org/PathwayBrowser/#/R-BTA-9036727 GAA hydrolyzes lysosomal glycogen IEA Bos taurus 17925 R-BTA-964759 https://reactome.org/PathwayBrowser/#/R-BTA-964759 Alternative endo-mannosidase I route IEA Bos taurus 17925 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 17925 R-CEL-1605591 https://reactome.org/PathwayBrowser/#/R-CEL-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Caenorhabditis elegans 17925 R-CEL-1606564 https://reactome.org/PathwayBrowser/#/R-CEL-1606564 GALC hydrolyzes GalCer IEA Caenorhabditis elegans 17925 R-CEL-1861788 https://reactome.org/PathwayBrowser/#/R-CEL-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Caenorhabditis elegans 17925 R-CEL-1861789 https://reactome.org/PathwayBrowser/#/R-CEL-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Caenorhabditis elegans 17925 R-CEL-188979 https://reactome.org/PathwayBrowser/#/R-CEL-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Caenorhabditis elegans 17925 R-CEL-189053 https://reactome.org/PathwayBrowser/#/R-CEL-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Caenorhabditis elegans 17925 R-CEL-189062 https://reactome.org/PathwayBrowser/#/R-CEL-189062 lactose + H2O => D-glucose + D-galactose IEA Caenorhabditis elegans 17925 R-CEL-189069 https://reactome.org/PathwayBrowser/#/R-CEL-189069 sucrose + H2O => glucose + fructose IEA Caenorhabditis elegans 17925 R-CEL-189102 https://reactome.org/PathwayBrowser/#/R-CEL-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Caenorhabditis elegans 17925 R-CEL-189242 https://reactome.org/PathwayBrowser/#/R-CEL-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Caenorhabditis elegans 17925 R-CEL-191101 https://reactome.org/PathwayBrowser/#/R-CEL-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 17925 R-CEL-191108 https://reactome.org/PathwayBrowser/#/R-CEL-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 17925 R-CEL-191114 https://reactome.org/PathwayBrowser/#/R-CEL-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Caenorhabditis elegans 17925 R-CEL-191116 https://reactome.org/PathwayBrowser/#/R-CEL-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Caenorhabditis elegans 17925 R-CEL-428779 https://reactome.org/PathwayBrowser/#/R-CEL-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Caenorhabditis elegans 17925 R-CEL-429036 https://reactome.org/PathwayBrowser/#/R-CEL-429036 SLC2A9 transports Fru, Glc, urate IEA Caenorhabditis elegans 17925 R-CEL-450095 https://reactome.org/PathwayBrowser/#/R-CEL-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Caenorhabditis elegans 17925 R-CEL-499981 https://reactome.org/PathwayBrowser/#/R-CEL-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Caenorhabditis elegans 17925 R-CEL-5339524 https://reactome.org/PathwayBrowser/#/R-CEL-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Caenorhabditis elegans 17925 R-CEL-5652172 https://reactome.org/PathwayBrowser/#/R-CEL-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Caenorhabditis elegans 17925 R-CEL-5653873 https://reactome.org/PathwayBrowser/#/R-CEL-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Caenorhabditis elegans 17925 R-CEL-5659861 https://reactome.org/PathwayBrowser/#/R-CEL-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 17925 R-CEL-5696021 https://reactome.org/PathwayBrowser/#/R-CEL-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Caenorhabditis elegans 17925 R-CEL-70420 https://reactome.org/PathwayBrowser/#/R-CEL-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Caenorhabditis elegans 17925 R-CEL-71593 https://reactome.org/PathwayBrowser/#/R-CEL-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Caenorhabditis elegans 17925 R-CEL-8981553 https://reactome.org/PathwayBrowser/#/R-CEL-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Caenorhabditis elegans 17925 R-CEL-8981564 https://reactome.org/PathwayBrowser/#/R-CEL-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Caenorhabditis elegans 17925 R-CEL-8981570 https://reactome.org/PathwayBrowser/#/R-CEL-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Caenorhabditis elegans 17925 R-CEL-8981574 https://reactome.org/PathwayBrowser/#/R-CEL-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Caenorhabditis elegans 17925 R-CFA-1605591 https://reactome.org/PathwayBrowser/#/R-CFA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Canis familiaris 17925 R-CFA-1606564 https://reactome.org/PathwayBrowser/#/R-CFA-1606564 GALC hydrolyzes GalCer IEA Canis familiaris 17925 R-CFA-170810 https://reactome.org/PathwayBrowser/#/R-CFA-170810 nucleoplasmic GCK1:GKRP complex => glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Canis familiaris 17925 R-CFA-1861788 https://reactome.org/PathwayBrowser/#/R-CFA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Canis familiaris 17925 R-CFA-1861789 https://reactome.org/PathwayBrowser/#/R-CFA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Canis familiaris 17925 R-CFA-188979 https://reactome.org/PathwayBrowser/#/R-CFA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Canis familiaris 17925 R-CFA-189053 https://reactome.org/PathwayBrowser/#/R-CFA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Canis familiaris 17925 R-CFA-189062 https://reactome.org/PathwayBrowser/#/R-CFA-189062 lactose + H2O => D-glucose + D-galactose IEA Canis familiaris 17925 R-CFA-189069 https://reactome.org/PathwayBrowser/#/R-CFA-189069 sucrose + H2O => glucose + fructose IEA Canis familiaris 17925 R-CFA-189102 https://reactome.org/PathwayBrowser/#/R-CFA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Canis familiaris 17925 R-CFA-189208 https://reactome.org/PathwayBrowser/#/R-CFA-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Canis familiaris 17925 R-CFA-189242 https://reactome.org/PathwayBrowser/#/R-CFA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Canis familiaris 17925 R-CFA-191101 https://reactome.org/PathwayBrowser/#/R-CFA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Canis familiaris 17925 R-CFA-191108 https://reactome.org/PathwayBrowser/#/R-CFA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Canis familiaris 17925 R-CFA-191114 https://reactome.org/PathwayBrowser/#/R-CFA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Canis familiaris 17925 R-CFA-191116 https://reactome.org/PathwayBrowser/#/R-CFA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Canis familiaris 17925 R-CFA-265682 https://reactome.org/PathwayBrowser/#/R-CFA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Canis familiaris 17925 R-CFA-3262512 https://reactome.org/PathwayBrowser/#/R-CFA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Canis familiaris 17925 R-CFA-3266566 https://reactome.org/PathwayBrowser/#/R-CFA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Canis familiaris 17925 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 17925 R-CFA-422048 https://reactome.org/PathwayBrowser/#/R-CFA-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Canis familiaris 17925 R-CFA-428779 https://reactome.org/PathwayBrowser/#/R-CFA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Canis familiaris 17925 R-CFA-429036 https://reactome.org/PathwayBrowser/#/R-CFA-429036 SLC2A9 transports Fru, Glc, urate IEA Canis familiaris 17925 R-CFA-429094 https://reactome.org/PathwayBrowser/#/R-CFA-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Canis familiaris 17925 R-CFA-429567 https://reactome.org/PathwayBrowser/#/R-CFA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Canis familiaris 17925 R-CFA-429613 https://reactome.org/PathwayBrowser/#/R-CFA-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Canis familiaris 17925 R-CFA-450095 https://reactome.org/PathwayBrowser/#/R-CFA-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Canis familiaris 17925 R-CFA-499981 https://reactome.org/PathwayBrowser/#/R-CFA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Canis familiaris 17925 R-CFA-5339524 https://reactome.org/PathwayBrowser/#/R-CFA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Canis familiaris 17925 R-CFA-5652172 https://reactome.org/PathwayBrowser/#/R-CFA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Canis familiaris 17925 R-CFA-5653873 https://reactome.org/PathwayBrowser/#/R-CFA-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Canis familiaris 17925 R-CFA-5653878 https://reactome.org/PathwayBrowser/#/R-CFA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Canis familiaris 17925 R-CFA-5659861 https://reactome.org/PathwayBrowser/#/R-CFA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Canis familiaris 17925 R-CFA-5696021 https://reactome.org/PathwayBrowser/#/R-CFA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Canis familiaris 17925 R-CFA-70420 https://reactome.org/PathwayBrowser/#/R-CFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Canis familiaris 17925 R-CFA-71593 https://reactome.org/PathwayBrowser/#/R-CFA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Canis familiaris 17925 R-CFA-71825 https://reactome.org/PathwayBrowser/#/R-CFA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Canis familiaris 17925 R-CFA-8875902 https://reactome.org/PathwayBrowser/#/R-CFA-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Canis familiaris 17925 R-CFA-8876319 https://reactome.org/PathwayBrowser/#/R-CFA-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Canis familiaris 17925 R-CFA-8932955 https://reactome.org/PathwayBrowser/#/R-CFA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Canis familiaris 17925 R-CFA-8981553 https://reactome.org/PathwayBrowser/#/R-CFA-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Canis familiaris 17925 R-CFA-8981564 https://reactome.org/PathwayBrowser/#/R-CFA-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Canis familiaris 17925 R-CFA-8981570 https://reactome.org/PathwayBrowser/#/R-CFA-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Canis familiaris 17925 R-CFA-8981574 https://reactome.org/PathwayBrowser/#/R-CFA-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Canis familiaris 17925 R-CFA-9036727 https://reactome.org/PathwayBrowser/#/R-CFA-9036727 GAA hydrolyzes lysosomal glycogen IEA Canis familiaris 17925 R-CFA-964759 https://reactome.org/PathwayBrowser/#/R-CFA-964759 Alternative endo-mannosidase I route IEA Canis familiaris 17925 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 17925 R-DDI-1861788 https://reactome.org/PathwayBrowser/#/R-DDI-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Dictyostelium discoideum 17925 R-DDI-189053 https://reactome.org/PathwayBrowser/#/R-DDI-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Dictyostelium discoideum 17925 R-DDI-189069 https://reactome.org/PathwayBrowser/#/R-DDI-189069 sucrose + H2O => glucose + fructose IEA Dictyostelium discoideum 17925 R-DDI-189102 https://reactome.org/PathwayBrowser/#/R-DDI-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Dictyostelium discoideum 17925 R-DDI-189242 https://reactome.org/PathwayBrowser/#/R-DDI-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Dictyostelium discoideum 17925 R-DDI-191101 https://reactome.org/PathwayBrowser/#/R-DDI-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 17925 R-DDI-191108 https://reactome.org/PathwayBrowser/#/R-DDI-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 17925 R-DDI-191116 https://reactome.org/PathwayBrowser/#/R-DDI-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Dictyostelium discoideum 17925 R-DDI-428779 https://reactome.org/PathwayBrowser/#/R-DDI-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Dictyostelium discoideum 17925 R-DDI-429036 https://reactome.org/PathwayBrowser/#/R-DDI-429036 SLC2A9 transports Fru, Glc, urate IEA Dictyostelium discoideum 17925 R-DDI-429094 https://reactome.org/PathwayBrowser/#/R-DDI-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Dictyostelium discoideum 17925 R-DDI-450095 https://reactome.org/PathwayBrowser/#/R-DDI-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Dictyostelium discoideum 17925 R-DDI-499981 https://reactome.org/PathwayBrowser/#/R-DDI-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Dictyostelium discoideum 17925 R-DDI-5339524 https://reactome.org/PathwayBrowser/#/R-DDI-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 17925 R-DDI-5652172 https://reactome.org/PathwayBrowser/#/R-DDI-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Dictyostelium discoideum 17925 R-DDI-5653873 https://reactome.org/PathwayBrowser/#/R-DDI-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Dictyostelium discoideum 17925 R-DDI-5659861 https://reactome.org/PathwayBrowser/#/R-DDI-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 17925 R-DDI-5696021 https://reactome.org/PathwayBrowser/#/R-DDI-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Dictyostelium discoideum 17925 R-DDI-71593 https://reactome.org/PathwayBrowser/#/R-DDI-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Dictyostelium discoideum 17925 R-DDI-8875902 https://reactome.org/PathwayBrowser/#/R-DDI-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 17925 R-DDI-8876319 https://reactome.org/PathwayBrowser/#/R-DDI-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Dictyostelium discoideum 17925 R-DDI-8981553 https://reactome.org/PathwayBrowser/#/R-DDI-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 17925 R-DDI-8981564 https://reactome.org/PathwayBrowser/#/R-DDI-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 17925 R-DDI-8981570 https://reactome.org/PathwayBrowser/#/R-DDI-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 17925 R-DDI-8981574 https://reactome.org/PathwayBrowser/#/R-DDI-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 17925 R-DDI-9036727 https://reactome.org/PathwayBrowser/#/R-DDI-9036727 GAA hydrolyzes lysosomal glycogen IEA Dictyostelium discoideum 17925 R-DME-1605591 https://reactome.org/PathwayBrowser/#/R-DME-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Drosophila melanogaster 17925 R-DME-1861788 https://reactome.org/PathwayBrowser/#/R-DME-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Drosophila melanogaster 17925 R-DME-1861789 https://reactome.org/PathwayBrowser/#/R-DME-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Drosophila melanogaster 17925 R-DME-188979 https://reactome.org/PathwayBrowser/#/R-DME-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Drosophila melanogaster 17925 R-DME-189062 https://reactome.org/PathwayBrowser/#/R-DME-189062 lactose + H2O => D-glucose + D-galactose IEA Drosophila melanogaster 17925 R-DME-189242 https://reactome.org/PathwayBrowser/#/R-DME-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Drosophila melanogaster 17925 R-DME-191114 https://reactome.org/PathwayBrowser/#/R-DME-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Drosophila melanogaster 17925 R-DME-265682 https://reactome.org/PathwayBrowser/#/R-DME-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Drosophila melanogaster 17925 R-DME-3262512 https://reactome.org/PathwayBrowser/#/R-DME-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Drosophila melanogaster 17925 R-DME-3266566 https://reactome.org/PathwayBrowser/#/R-DME-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Drosophila melanogaster 17925 R-DME-428779 https://reactome.org/PathwayBrowser/#/R-DME-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Drosophila melanogaster 17925 R-DME-429036 https://reactome.org/PathwayBrowser/#/R-DME-429036 SLC2A9 transports Fru, Glc, urate IEA Drosophila melanogaster 17925 R-DME-429094 https://reactome.org/PathwayBrowser/#/R-DME-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Drosophila melanogaster 17925 R-DME-450095 https://reactome.org/PathwayBrowser/#/R-DME-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Drosophila melanogaster 17925 R-DME-499981 https://reactome.org/PathwayBrowser/#/R-DME-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Drosophila melanogaster 17925 R-DME-5339524 https://reactome.org/PathwayBrowser/#/R-DME-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Drosophila melanogaster 17925 R-DME-5652172 https://reactome.org/PathwayBrowser/#/R-DME-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Drosophila melanogaster 17925 R-DME-5653873 https://reactome.org/PathwayBrowser/#/R-DME-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Drosophila melanogaster 17925 R-DME-5653878 https://reactome.org/PathwayBrowser/#/R-DME-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Drosophila melanogaster 17925 R-DME-70420 https://reactome.org/PathwayBrowser/#/R-DME-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Drosophila melanogaster 17925 R-DME-71593 https://reactome.org/PathwayBrowser/#/R-DME-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Drosophila melanogaster 17925 R-DME-71825 https://reactome.org/PathwayBrowser/#/R-DME-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Drosophila melanogaster 17925 R-DME-8981553 https://reactome.org/PathwayBrowser/#/R-DME-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Drosophila melanogaster 17925 R-DME-8981564 https://reactome.org/PathwayBrowser/#/R-DME-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Drosophila melanogaster 17925 R-DME-8981570 https://reactome.org/PathwayBrowser/#/R-DME-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Drosophila melanogaster 17925 R-DME-8981574 https://reactome.org/PathwayBrowser/#/R-DME-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Drosophila melanogaster 17925 R-DME-964759 https://reactome.org/PathwayBrowser/#/R-DME-964759 Alternative endo-mannosidase I route IEA Drosophila melanogaster 17925 R-DRE-1861788 https://reactome.org/PathwayBrowser/#/R-DRE-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Danio rerio 17925 R-DRE-1861789 https://reactome.org/PathwayBrowser/#/R-DRE-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Danio rerio 17925 R-DRE-188979 https://reactome.org/PathwayBrowser/#/R-DRE-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Danio rerio 17925 R-DRE-189208 https://reactome.org/PathwayBrowser/#/R-DRE-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Danio rerio 17925 R-DRE-189242 https://reactome.org/PathwayBrowser/#/R-DRE-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Danio rerio 17925 R-DRE-191114 https://reactome.org/PathwayBrowser/#/R-DRE-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Danio rerio 17925 R-DRE-3262512 https://reactome.org/PathwayBrowser/#/R-DRE-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Danio rerio 17925 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 17925 R-DRE-422048 https://reactome.org/PathwayBrowser/#/R-DRE-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Danio rerio 17925 R-DRE-429094 https://reactome.org/PathwayBrowser/#/R-DRE-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Danio rerio 17925 R-DRE-429567 https://reactome.org/PathwayBrowser/#/R-DRE-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Danio rerio 17925 R-DRE-429613 https://reactome.org/PathwayBrowser/#/R-DRE-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Danio rerio 17925 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 17925 R-DRE-450095 https://reactome.org/PathwayBrowser/#/R-DRE-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Danio rerio 17925 R-DRE-499981 https://reactome.org/PathwayBrowser/#/R-DRE-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Danio rerio 17925 R-DRE-5339524 https://reactome.org/PathwayBrowser/#/R-DRE-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Danio rerio 17925 R-DRE-5652172 https://reactome.org/PathwayBrowser/#/R-DRE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Danio rerio 17925 R-DRE-5653873 https://reactome.org/PathwayBrowser/#/R-DRE-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Danio rerio 17925 R-DRE-5653878 https://reactome.org/PathwayBrowser/#/R-DRE-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Danio rerio 17925 R-DRE-5696021 https://reactome.org/PathwayBrowser/#/R-DRE-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Danio rerio 17925 R-DRE-70420 https://reactome.org/PathwayBrowser/#/R-DRE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Danio rerio 17925 R-DRE-8875902 https://reactome.org/PathwayBrowser/#/R-DRE-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Danio rerio 17925 R-DRE-8876319 https://reactome.org/PathwayBrowser/#/R-DRE-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Danio rerio 17925 R-DRE-8932955 https://reactome.org/PathwayBrowser/#/R-DRE-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Danio rerio 17925 R-DRE-8981553 https://reactome.org/PathwayBrowser/#/R-DRE-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Danio rerio 17925 R-DRE-8981564 https://reactome.org/PathwayBrowser/#/R-DRE-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Danio rerio 17925 R-DRE-8981574 https://reactome.org/PathwayBrowser/#/R-DRE-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Danio rerio 17925 R-DRE-964759 https://reactome.org/PathwayBrowser/#/R-DRE-964759 Alternative endo-mannosidase I route IEA Danio rerio 17925 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 17925 R-GGA-1605591 https://reactome.org/PathwayBrowser/#/R-GGA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Gallus gallus 17925 R-GGA-1606564 https://reactome.org/PathwayBrowser/#/R-GGA-1606564 GALC hydrolyzes GalCer IEA Gallus gallus 17925 R-GGA-1861788 https://reactome.org/PathwayBrowser/#/R-GGA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Gallus gallus 17925 R-GGA-188979 https://reactome.org/PathwayBrowser/#/R-GGA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Gallus gallus 17925 R-GGA-189053 https://reactome.org/PathwayBrowser/#/R-GGA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Gallus gallus 17925 R-GGA-189062 https://reactome.org/PathwayBrowser/#/R-GGA-189062 lactose + H2O => D-glucose + D-galactose IEA Gallus gallus 17925 R-GGA-189069 https://reactome.org/PathwayBrowser/#/R-GGA-189069 sucrose + H2O => glucose + fructose IEA Gallus gallus 17925 R-GGA-189102 https://reactome.org/PathwayBrowser/#/R-GGA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Gallus gallus 17925 R-GGA-189242 https://reactome.org/PathwayBrowser/#/R-GGA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Gallus gallus 17925 R-GGA-191101 https://reactome.org/PathwayBrowser/#/R-GGA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Gallus gallus 17925 R-GGA-191108 https://reactome.org/PathwayBrowser/#/R-GGA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus 17925 R-GGA-191114 https://reactome.org/PathwayBrowser/#/R-GGA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Gallus gallus 17925 R-GGA-191116 https://reactome.org/PathwayBrowser/#/R-GGA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Gallus gallus 17925 R-GGA-265682 https://reactome.org/PathwayBrowser/#/R-GGA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Gallus gallus 17925 R-GGA-3262512 https://reactome.org/PathwayBrowser/#/R-GGA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Gallus gallus 17925 R-GGA-3266566 https://reactome.org/PathwayBrowser/#/R-GGA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Gallus gallus 17925 R-GGA-352840 https://reactome.org/PathwayBrowser/#/R-GGA-352840 glucose + ATP => glucose 6-phosphate + ADP TAS Gallus gallus 17925 R-GGA-352864 https://reactome.org/PathwayBrowser/#/R-GGA-352864 glucose [extracellular] <=> glucose [cytosol] TAS Gallus gallus 17925 R-GGA-352867 https://reactome.org/PathwayBrowser/#/R-GGA-352867 glucose [cytosol] <=> glucose [extracellular] TAS Gallus gallus 17925 R-GGA-353058 https://reactome.org/PathwayBrowser/#/R-GGA-353058 glucose 6-phosphate + H2O => glucose + phosphate IEA Gallus gallus 17925 R-GGA-376886 https://reactome.org/PathwayBrowser/#/R-GGA-376886 Efflux of glucose and orthophosphate from the endoplasmic reticulum TAS Gallus gallus 17925 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 17925 R-GGA-422048 https://reactome.org/PathwayBrowser/#/R-GGA-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Gallus gallus 17925 R-GGA-428779 https://reactome.org/PathwayBrowser/#/R-GGA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Gallus gallus 17925 R-GGA-429036 https://reactome.org/PathwayBrowser/#/R-GGA-429036 SLC2A9 transports Fru, Glc, urate IEA Gallus gallus 17925 R-GGA-429094 https://reactome.org/PathwayBrowser/#/R-GGA-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Gallus gallus 17925 R-GGA-429567 https://reactome.org/PathwayBrowser/#/R-GGA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Gallus gallus 17925 R-GGA-450095 https://reactome.org/PathwayBrowser/#/R-GGA-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Gallus gallus 17925 R-GGA-499981 https://reactome.org/PathwayBrowser/#/R-GGA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Gallus gallus 17925 R-GGA-5339524 https://reactome.org/PathwayBrowser/#/R-GGA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus 17925 R-GGA-5652172 https://reactome.org/PathwayBrowser/#/R-GGA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Gallus gallus 17925 R-GGA-5653873 https://reactome.org/PathwayBrowser/#/R-GGA-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Gallus gallus 17925 R-GGA-5653878 https://reactome.org/PathwayBrowser/#/R-GGA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Gallus gallus 17925 R-GGA-5659861 https://reactome.org/PathwayBrowser/#/R-GGA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus 17925 R-GGA-5696021 https://reactome.org/PathwayBrowser/#/R-GGA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Gallus gallus 17925 R-GGA-70420 https://reactome.org/PathwayBrowser/#/R-GGA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Gallus gallus 17925 R-GGA-71593 https://reactome.org/PathwayBrowser/#/R-GGA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Gallus gallus 17925 R-GGA-71825 https://reactome.org/PathwayBrowser/#/R-GGA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Gallus gallus 17925 R-GGA-8875902 https://reactome.org/PathwayBrowser/#/R-GGA-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Gallus gallus 17925 R-GGA-8932955 https://reactome.org/PathwayBrowser/#/R-GGA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Gallus gallus 17925 R-GGA-8981553 https://reactome.org/PathwayBrowser/#/R-GGA-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus 17925 R-GGA-8981564 https://reactome.org/PathwayBrowser/#/R-GGA-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus 17925 R-GGA-8981570 https://reactome.org/PathwayBrowser/#/R-GGA-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus 17925 R-GGA-8981574 https://reactome.org/PathwayBrowser/#/R-GGA-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus 17925 R-GGA-964759 https://reactome.org/PathwayBrowser/#/R-GGA-964759 Alternative endo-mannosidase I route IEA Gallus gallus 17925 R-HSA-1605591 https://reactome.org/PathwayBrowser/#/R-HSA-1605591 GBA1:SAPC hydrolyzes GlcCer TAS Homo sapiens 17925 R-HSA-1606564 https://reactome.org/PathwayBrowser/#/R-HSA-1606564 GALC hydrolyzes GalCer TAS Homo sapiens 17925 R-HSA-170810 https://reactome.org/PathwayBrowser/#/R-HSA-170810 nucleoplasmic GCK1:GKRP complex => glucokinase (GCK1) + glucokinase regulatory protein (GKRP) TAS Homo sapiens 17925 R-HSA-1861788 https://reactome.org/PathwayBrowser/#/R-HSA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) TAS Homo sapiens 17925 R-HSA-1861789 https://reactome.org/PathwayBrowser/#/R-HSA-1861789 GBA3 hydrolyzes GlcCer (cytosol) TAS Homo sapiens 17925 R-HSA-188979 https://reactome.org/PathwayBrowser/#/R-HSA-188979 Digestion of linear starch (amylose) by extracellular amylase TAS Homo sapiens 17925 R-HSA-188985 https://reactome.org/PathwayBrowser/#/R-HSA-188985 trehalose + H2O => 2 D-glucose IEA Homo sapiens 17925 R-HSA-189053 https://reactome.org/PathwayBrowser/#/R-HSA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose TAS Homo sapiens 17925 R-HSA-189062 https://reactome.org/PathwayBrowser/#/R-HSA-189062 lactose + H2O => D-glucose + D-galactose TAS Homo sapiens 17925 R-HSA-189069 https://reactome.org/PathwayBrowser/#/R-HSA-189069 sucrose + H2O => glucose + fructose TAS Homo sapiens 17925 R-HSA-189102 https://reactome.org/PathwayBrowser/#/R-HSA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) TAS Homo sapiens 17925 R-HSA-189208 https://reactome.org/PathwayBrowser/#/R-HSA-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-189242 https://reactome.org/PathwayBrowser/#/R-HSA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region TAS Homo sapiens 17925 R-HSA-191101 https://reactome.org/PathwayBrowser/#/R-HSA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) TAS Homo sapiens 17925 R-HSA-191108 https://reactome.org/PathwayBrowser/#/R-HSA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) TAS Homo sapiens 17925 R-HSA-191114 https://reactome.org/PathwayBrowser/#/R-HSA-191114 Digestion of branched starch (amylopectin) by extracellular amylase TAS Homo sapiens 17925 R-HSA-191116 https://reactome.org/PathwayBrowser/#/R-HSA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) TAS Homo sapiens 17925 R-HSA-198458 https://reactome.org/PathwayBrowser/#/R-HSA-198458 Efflux of Glc from the endoplasmic reticulum TAS Homo sapiens 17925 R-HSA-265682 https://reactome.org/PathwayBrowser/#/R-HSA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel TAS Homo sapiens 17925 R-HSA-3262512 https://reactome.org/PathwayBrowser/#/R-HSA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) TAS Homo sapiens 17925 R-HSA-3266566 https://reactome.org/PathwayBrowser/#/R-HSA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) TAS Homo sapiens 17925 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 17925 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 17925 R-HSA-422048 https://reactome.org/PathwayBrowser/#/R-HSA-422048 Acyl Ghrelin and C-Ghrelin are secreted TAS Homo sapiens 17925 R-HSA-428779 https://reactome.org/PathwayBrowser/#/R-HSA-428779 GLUT7 and GLUT11 transport glucose and fructose TAS Homo sapiens 17925 R-HSA-429036 https://reactome.org/PathwayBrowser/#/R-HSA-429036 SLC2A9 transports Fru, Glc, urate TAS Homo sapiens 17925 R-HSA-429094 https://reactome.org/PathwayBrowser/#/R-HSA-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-429567 https://reactome.org/PathwayBrowser/#/R-HSA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 TAS Homo sapiens 17925 R-HSA-429613 https://reactome.org/PathwayBrowser/#/R-HSA-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 17925 R-HSA-450095 https://reactome.org/PathwayBrowser/#/R-HSA-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region TAS Homo sapiens 17925 R-HSA-499981 https://reactome.org/PathwayBrowser/#/R-HSA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 TAS Homo sapiens 17925 R-HSA-532667 https://reactome.org/PathwayBrowser/#/R-HSA-532667 Removal of the second glucose by glucosidase II TAS Homo sapiens 17925 R-HSA-532678 https://reactome.org/PathwayBrowser/#/R-HSA-532678 Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase TAS Homo sapiens 17925 R-HSA-5339524 https://reactome.org/PathwayBrowser/#/R-HSA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-548890 https://reactome.org/PathwayBrowser/#/R-HSA-548890 Removal of the third glucose by glucosidase II and release from the chaperone TAS Homo sapiens 17925 R-HSA-5621888 https://reactome.org/PathwayBrowser/#/R-HSA-5621888 Defective HK1 does not phosphorylate Glc to form G6P TAS Homo sapiens 17925 R-HSA-5621918 https://reactome.org/PathwayBrowser/#/R-HSA-5621918 Defective GCK does not phosphorylate Glc to form G6P TAS Homo sapiens 17925 R-HSA-5632804 https://reactome.org/PathwayBrowser/#/R-HSA-5632804 SLC2A1 tetramer does not transport Glc from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-5632871 https://reactome.org/PathwayBrowser/#/R-HSA-5632871 Defective SLC2A10 does not transport Glc from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-5638209 https://reactome.org/PathwayBrowser/#/R-HSA-5638209 Defective SLC2A9 does not transport Fru, Glc, urate TAS Homo sapiens 17925 R-HSA-5638222 https://reactome.org/PathwayBrowser/#/R-HSA-5638222 Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region TAS Homo sapiens 17925 R-HSA-5652172 https://reactome.org/PathwayBrowser/#/R-HSA-5652172 AKR1B1 reduces Glc to D-sorbitol TAS Homo sapiens 17925 R-HSA-5653873 https://reactome.org/PathwayBrowser/#/R-HSA-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen TAS Homo sapiens 17925 R-HSA-5653878 https://reactome.org/PathwayBrowser/#/R-HSA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac TAS Homo sapiens 17925 R-HSA-5656356 https://reactome.org/PathwayBrowser/#/R-HSA-5656356 Defective SLC5A1 does not cotransport Glc and Na+ TAS Homo sapiens 17925 R-HSA-5658163 https://reactome.org/PathwayBrowser/#/R-HSA-5658163 Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-5659861 https://reactome.org/PathwayBrowser/#/R-HSA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) TAS Homo sapiens 17925 R-HSA-5696021 https://reactome.org/PathwayBrowser/#/R-HSA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P TAS Homo sapiens 17925 R-HSA-70420 https://reactome.org/PathwayBrowser/#/R-HSA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P TAS Homo sapiens 17925 R-HSA-71593 https://reactome.org/PathwayBrowser/#/R-HSA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose TAS Homo sapiens 17925 R-HSA-71825 https://reactome.org/PathwayBrowser/#/R-HSA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) TAS Homo sapiens 17925 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 17925 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 17925 R-HSA-8875902 https://reactome.org/PathwayBrowser/#/R-HSA-8875902 SLC45A3 transports Glc from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-8876319 https://reactome.org/PathwayBrowser/#/R-HSA-8876319 SLC50A1 transports Glc from cytosol to extracellular region TAS Homo sapiens 17925 R-HSA-8932955 https://reactome.org/PathwayBrowser/#/R-HSA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-8981553 https://reactome.org/PathwayBrowser/#/R-HSA-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-8981564 https://reactome.org/PathwayBrowser/#/R-HSA-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-8981570 https://reactome.org/PathwayBrowser/#/R-HSA-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-8981574 https://reactome.org/PathwayBrowser/#/R-HSA-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol TAS Homo sapiens 17925 R-HSA-9036727 https://reactome.org/PathwayBrowser/#/R-HSA-9036727 GAA hydrolyzes lysosomal glycogen TAS Homo sapiens 17925 R-HSA-964759 https://reactome.org/PathwayBrowser/#/R-HSA-964759 Alternative endo-mannosidase I route TAS Homo sapiens 17925 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 17925 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 17925 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 17925 R-MMU-1605591 https://reactome.org/PathwayBrowser/#/R-MMU-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Mus musculus 17925 R-MMU-1606564 https://reactome.org/PathwayBrowser/#/R-MMU-1606564 GALC hydrolyzes GalCer IEA Mus musculus 17925 R-MMU-170810 https://reactome.org/PathwayBrowser/#/R-MMU-170810 nucleoplasmic GCK1:GKRP complex => glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Mus musculus 17925 R-MMU-1861788 https://reactome.org/PathwayBrowser/#/R-MMU-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Mus musculus 17925 R-MMU-188979 https://reactome.org/PathwayBrowser/#/R-MMU-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Mus musculus 17925 R-MMU-189053 https://reactome.org/PathwayBrowser/#/R-MMU-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Mus musculus 17925 R-MMU-189062 https://reactome.org/PathwayBrowser/#/R-MMU-189062 lactose + H2O => D-glucose + D-galactose IEA Mus musculus 17925 R-MMU-189069 https://reactome.org/PathwayBrowser/#/R-MMU-189069 sucrose + H2O => glucose + fructose IEA Mus musculus 17925 R-MMU-189102 https://reactome.org/PathwayBrowser/#/R-MMU-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Mus musculus 17925 R-MMU-189208 https://reactome.org/PathwayBrowser/#/R-MMU-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Mus musculus 17925 R-MMU-189242 https://reactome.org/PathwayBrowser/#/R-MMU-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Mus musculus 17925 R-MMU-191101 https://reactome.org/PathwayBrowser/#/R-MMU-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Mus musculus 17925 R-MMU-191108 https://reactome.org/PathwayBrowser/#/R-MMU-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Mus musculus 17925 R-MMU-191114 https://reactome.org/PathwayBrowser/#/R-MMU-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Mus musculus 17925 R-MMU-191116 https://reactome.org/PathwayBrowser/#/R-MMU-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Mus musculus 17925 R-MMU-265682 https://reactome.org/PathwayBrowser/#/R-MMU-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Mus musculus 17925 R-MMU-3262512 https://reactome.org/PathwayBrowser/#/R-MMU-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Mus musculus 17925 R-MMU-3266566 https://reactome.org/PathwayBrowser/#/R-MMU-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Mus musculus 17925 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 17925 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 17925 R-MMU-422048 https://reactome.org/PathwayBrowser/#/R-MMU-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Mus musculus 17925 R-MMU-428779 https://reactome.org/PathwayBrowser/#/R-MMU-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Mus musculus 17925 R-MMU-429036 https://reactome.org/PathwayBrowser/#/R-MMU-429036 SLC2A9 transports Fru, Glc, urate IEA Mus musculus 17925 R-MMU-429094 https://reactome.org/PathwayBrowser/#/R-MMU-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Mus musculus 17925 R-MMU-429567 https://reactome.org/PathwayBrowser/#/R-MMU-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Mus musculus 17925 R-MMU-429613 https://reactome.org/PathwayBrowser/#/R-MMU-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Mus musculus 17925 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 17925 R-MMU-450095 https://reactome.org/PathwayBrowser/#/R-MMU-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Mus musculus 17925 R-MMU-499981 https://reactome.org/PathwayBrowser/#/R-MMU-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Mus musculus 17925 R-MMU-5339524 https://reactome.org/PathwayBrowser/#/R-MMU-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Mus musculus 17925 R-MMU-5652172 https://reactome.org/PathwayBrowser/#/R-MMU-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Mus musculus 17925 R-MMU-5653873 https://reactome.org/PathwayBrowser/#/R-MMU-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Mus musculus 17925 R-MMU-5653878 https://reactome.org/PathwayBrowser/#/R-MMU-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Mus musculus 17925 R-MMU-5659861 https://reactome.org/PathwayBrowser/#/R-MMU-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Mus musculus 17925 R-MMU-5696021 https://reactome.org/PathwayBrowser/#/R-MMU-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Mus musculus 17925 R-MMU-70420 https://reactome.org/PathwayBrowser/#/R-MMU-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Mus musculus 17925 R-MMU-71593 https://reactome.org/PathwayBrowser/#/R-MMU-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Mus musculus 17925 R-MMU-71825 https://reactome.org/PathwayBrowser/#/R-MMU-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Mus musculus 17925 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 17925 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 17925 R-MMU-8875902 https://reactome.org/PathwayBrowser/#/R-MMU-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Mus musculus 17925 R-MMU-8876319 https://reactome.org/PathwayBrowser/#/R-MMU-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Mus musculus 17925 R-MMU-8932955 https://reactome.org/PathwayBrowser/#/R-MMU-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Mus musculus 17925 R-MMU-8981553 https://reactome.org/PathwayBrowser/#/R-MMU-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Mus musculus 17925 R-MMU-8981564 https://reactome.org/PathwayBrowser/#/R-MMU-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Mus musculus 17925 R-MMU-8981570 https://reactome.org/PathwayBrowser/#/R-MMU-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Mus musculus 17925 R-MMU-8981574 https://reactome.org/PathwayBrowser/#/R-MMU-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Mus musculus 17925 R-MMU-9036727 https://reactome.org/PathwayBrowser/#/R-MMU-9036727 GAA hydrolyzes lysosomal glycogen IEA Mus musculus 17925 R-MMU-964759 https://reactome.org/PathwayBrowser/#/R-MMU-964759 Alternative endo-mannosidase I route IEA Mus musculus 17925 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 17925 R-OCU-189019 https://reactome.org/PathwayBrowser/#/R-OCU-189019 trehalose + H2O => 2 D-glucose TAS Oryctolagus cuniculus 17925 R-PFA-189242 https://reactome.org/PathwayBrowser/#/R-PFA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Plasmodium falciparum 17925 R-PFA-428779 https://reactome.org/PathwayBrowser/#/R-PFA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Plasmodium falciparum 17925 R-PFA-429036 https://reactome.org/PathwayBrowser/#/R-PFA-429036 SLC2A9 transports Fru, Glc, urate IEA Plasmodium falciparum 17925 R-PFA-450095 https://reactome.org/PathwayBrowser/#/R-PFA-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Plasmodium falciparum 17925 R-PFA-499981 https://reactome.org/PathwayBrowser/#/R-PFA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Plasmodium falciparum 17925 R-PFA-5339524 https://reactome.org/PathwayBrowser/#/R-PFA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Plasmodium falciparum 17925 R-PFA-5653873 https://reactome.org/PathwayBrowser/#/R-PFA-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Plasmodium falciparum 17925 R-PFA-70420 https://reactome.org/PathwayBrowser/#/R-PFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Plasmodium falciparum 17925 R-PFA-8876319 https://reactome.org/PathwayBrowser/#/R-PFA-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Plasmodium falciparum 17925 R-PFA-8981553 https://reactome.org/PathwayBrowser/#/R-PFA-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Plasmodium falciparum 17925 R-PFA-8981564 https://reactome.org/PathwayBrowser/#/R-PFA-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Plasmodium falciparum 17925 R-PFA-8981570 https://reactome.org/PathwayBrowser/#/R-PFA-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Plasmodium falciparum 17925 R-PFA-8981574 https://reactome.org/PathwayBrowser/#/R-PFA-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Plasmodium falciparum 17925 R-RNO-1605591 https://reactome.org/PathwayBrowser/#/R-RNO-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Rattus norvegicus 17925 R-RNO-1606564 https://reactome.org/PathwayBrowser/#/R-RNO-1606564 GALC hydrolyzes GalCer IEA Rattus norvegicus 17925 R-RNO-170810 https://reactome.org/PathwayBrowser/#/R-RNO-170810 nucleoplasmic GCK1:GKRP complex => glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Rattus norvegicus 17925 R-RNO-1861788 https://reactome.org/PathwayBrowser/#/R-RNO-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Rattus norvegicus 17925 R-RNO-1861789 https://reactome.org/PathwayBrowser/#/R-RNO-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Rattus norvegicus 17925 R-RNO-188979 https://reactome.org/PathwayBrowser/#/R-RNO-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Rattus norvegicus 17925 R-RNO-189053 https://reactome.org/PathwayBrowser/#/R-RNO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Rattus norvegicus 17925 R-RNO-189062 https://reactome.org/PathwayBrowser/#/R-RNO-189062 lactose + H2O => D-glucose + D-galactose IEA Rattus norvegicus 17925 R-RNO-189069 https://reactome.org/PathwayBrowser/#/R-RNO-189069 sucrose + H2O => glucose + fructose IEA Rattus norvegicus 17925 R-RNO-189208 https://reactome.org/PathwayBrowser/#/R-RNO-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Rattus norvegicus 17925 R-RNO-189242 https://reactome.org/PathwayBrowser/#/R-RNO-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Rattus norvegicus 17925 R-RNO-191101 https://reactome.org/PathwayBrowser/#/R-RNO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 17925 R-RNO-191108 https://reactome.org/PathwayBrowser/#/R-RNO-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 17925 R-RNO-191114 https://reactome.org/PathwayBrowser/#/R-RNO-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Rattus norvegicus 17925 R-RNO-265682 https://reactome.org/PathwayBrowser/#/R-RNO-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Rattus norvegicus 17925 R-RNO-3262512 https://reactome.org/PathwayBrowser/#/R-RNO-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Rattus norvegicus 17925 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 17925 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 17925 R-RNO-422048 https://reactome.org/PathwayBrowser/#/R-RNO-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Rattus norvegicus 17925 R-RNO-428779 https://reactome.org/PathwayBrowser/#/R-RNO-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Rattus norvegicus 17925 R-RNO-429036 https://reactome.org/PathwayBrowser/#/R-RNO-429036 SLC2A9 transports Fru, Glc, urate IEA Rattus norvegicus 17925 R-RNO-429094 https://reactome.org/PathwayBrowser/#/R-RNO-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Rattus norvegicus 17925 R-RNO-429567 https://reactome.org/PathwayBrowser/#/R-RNO-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Rattus norvegicus 17925 R-RNO-429613 https://reactome.org/PathwayBrowser/#/R-RNO-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Rattus norvegicus 17925 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 17925 R-RNO-450095 https://reactome.org/PathwayBrowser/#/R-RNO-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Rattus norvegicus 17925 R-RNO-499981 https://reactome.org/PathwayBrowser/#/R-RNO-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Rattus norvegicus 17925 R-RNO-5339524 https://reactome.org/PathwayBrowser/#/R-RNO-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Rattus norvegicus 17925 R-RNO-5652172 https://reactome.org/PathwayBrowser/#/R-RNO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Rattus norvegicus 17925 R-RNO-5653873 https://reactome.org/PathwayBrowser/#/R-RNO-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Rattus norvegicus 17925 R-RNO-5659861 https://reactome.org/PathwayBrowser/#/R-RNO-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 17925 R-RNO-5696021 https://reactome.org/PathwayBrowser/#/R-RNO-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Rattus norvegicus 17925 R-RNO-70420 https://reactome.org/PathwayBrowser/#/R-RNO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Rattus norvegicus 17925 R-RNO-71593 https://reactome.org/PathwayBrowser/#/R-RNO-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Rattus norvegicus 17925 R-RNO-71825 https://reactome.org/PathwayBrowser/#/R-RNO-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Rattus norvegicus 17925 R-RNO-8875902 https://reactome.org/PathwayBrowser/#/R-RNO-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Rattus norvegicus 17925 R-RNO-8876319 https://reactome.org/PathwayBrowser/#/R-RNO-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Rattus norvegicus 17925 R-RNO-8932955 https://reactome.org/PathwayBrowser/#/R-RNO-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Rattus norvegicus 17925 R-RNO-8981553 https://reactome.org/PathwayBrowser/#/R-RNO-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Rattus norvegicus 17925 R-RNO-8981564 https://reactome.org/PathwayBrowser/#/R-RNO-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Rattus norvegicus 17925 R-RNO-8981570 https://reactome.org/PathwayBrowser/#/R-RNO-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Rattus norvegicus 17925 R-RNO-8981574 https://reactome.org/PathwayBrowser/#/R-RNO-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Rattus norvegicus 17925 R-RNO-9036727 https://reactome.org/PathwayBrowser/#/R-RNO-9036727 GAA hydrolyzes lysosomal glycogen IEA Rattus norvegicus 17925 R-RNO-964759 https://reactome.org/PathwayBrowser/#/R-RNO-964759 Alternative endo-mannosidase I route IEA Rattus norvegicus 17925 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 17925 R-SCE-189242 https://reactome.org/PathwayBrowser/#/R-SCE-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Saccharomyces cerevisiae 17925 R-SCE-428779 https://reactome.org/PathwayBrowser/#/R-SCE-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Saccharomyces cerevisiae 17925 R-SCE-429036 https://reactome.org/PathwayBrowser/#/R-SCE-429036 SLC2A9 transports Fru, Glc, urate IEA Saccharomyces cerevisiae 17925 R-SCE-450095 https://reactome.org/PathwayBrowser/#/R-SCE-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Saccharomyces cerevisiae 17925 R-SCE-499981 https://reactome.org/PathwayBrowser/#/R-SCE-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Saccharomyces cerevisiae 17925 R-SCE-5339524 https://reactome.org/PathwayBrowser/#/R-SCE-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Saccharomyces cerevisiae 17925 R-SCE-5652172 https://reactome.org/PathwayBrowser/#/R-SCE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Saccharomyces cerevisiae 17925 R-SCE-5653873 https://reactome.org/PathwayBrowser/#/R-SCE-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Saccharomyces cerevisiae 17925 R-SCE-70420 https://reactome.org/PathwayBrowser/#/R-SCE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Saccharomyces cerevisiae 17925 R-SCE-71593 https://reactome.org/PathwayBrowser/#/R-SCE-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Saccharomyces cerevisiae 17925 R-SCE-8981553 https://reactome.org/PathwayBrowser/#/R-SCE-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Saccharomyces cerevisiae 17925 R-SCE-8981564 https://reactome.org/PathwayBrowser/#/R-SCE-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Saccharomyces cerevisiae 17925 R-SCE-8981570 https://reactome.org/PathwayBrowser/#/R-SCE-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Saccharomyces cerevisiae 17925 R-SCE-8981574 https://reactome.org/PathwayBrowser/#/R-SCE-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Saccharomyces cerevisiae 17925 R-SPO-189053 https://reactome.org/PathwayBrowser/#/R-SPO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Schizosaccharomyces pombe 17925 R-SPO-189069 https://reactome.org/PathwayBrowser/#/R-SPO-189069 sucrose + H2O => glucose + fructose IEA Schizosaccharomyces pombe 17925 R-SPO-189102 https://reactome.org/PathwayBrowser/#/R-SPO-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Schizosaccharomyces pombe 17925 R-SPO-191101 https://reactome.org/PathwayBrowser/#/R-SPO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 17925 R-SPO-191108 https://reactome.org/PathwayBrowser/#/R-SPO-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 17925 R-SPO-191116 https://reactome.org/PathwayBrowser/#/R-SPO-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Schizosaccharomyces pombe 17925 R-SPO-5652172 https://reactome.org/PathwayBrowser/#/R-SPO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Schizosaccharomyces pombe 17925 R-SPO-5659861 https://reactome.org/PathwayBrowser/#/R-SPO-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 17925 R-SPO-70420 https://reactome.org/PathwayBrowser/#/R-SPO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Schizosaccharomyces pombe 17925 R-SPO-8875902 https://reactome.org/PathwayBrowser/#/R-SPO-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Schizosaccharomyces pombe 17925 R-SPO-9036727 https://reactome.org/PathwayBrowser/#/R-SPO-9036727 GAA hydrolyzes lysosomal glycogen IEA Schizosaccharomyces pombe 17925 R-SSC-1605591 https://reactome.org/PathwayBrowser/#/R-SSC-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Sus scrofa 17925 R-SSC-1606564 https://reactome.org/PathwayBrowser/#/R-SSC-1606564 GALC hydrolyzes GalCer IEA Sus scrofa 17925 R-SSC-1861788 https://reactome.org/PathwayBrowser/#/R-SSC-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Sus scrofa 17925 R-SSC-1861789 https://reactome.org/PathwayBrowser/#/R-SSC-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Sus scrofa 17925 R-SSC-188979 https://reactome.org/PathwayBrowser/#/R-SSC-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Sus scrofa 17925 R-SSC-189053 https://reactome.org/PathwayBrowser/#/R-SSC-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Sus scrofa 17925 R-SSC-189062 https://reactome.org/PathwayBrowser/#/R-SSC-189062 lactose + H2O => D-glucose + D-galactose IEA Sus scrofa 17925 R-SSC-189069 https://reactome.org/PathwayBrowser/#/R-SSC-189069 sucrose + H2O => glucose + fructose IEA Sus scrofa 17925 R-SSC-189102 https://reactome.org/PathwayBrowser/#/R-SSC-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Sus scrofa 17925 R-SSC-189208 https://reactome.org/PathwayBrowser/#/R-SSC-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Sus scrofa 17925 R-SSC-189242 https://reactome.org/PathwayBrowser/#/R-SSC-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Sus scrofa 17925 R-SSC-191101 https://reactome.org/PathwayBrowser/#/R-SSC-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Sus scrofa 17925 R-SSC-191108 https://reactome.org/PathwayBrowser/#/R-SSC-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Sus scrofa 17925 R-SSC-191114 https://reactome.org/PathwayBrowser/#/R-SSC-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Sus scrofa 17925 R-SSC-191116 https://reactome.org/PathwayBrowser/#/R-SSC-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Sus scrofa 17925 R-SSC-265682 https://reactome.org/PathwayBrowser/#/R-SSC-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Sus scrofa 17925 R-SSC-3262512 https://reactome.org/PathwayBrowser/#/R-SSC-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Sus scrofa 17925 R-SSC-3266566 https://reactome.org/PathwayBrowser/#/R-SSC-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Sus scrofa 17925 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 17925 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 17925 R-SSC-422048 https://reactome.org/PathwayBrowser/#/R-SSC-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Sus scrofa 17925 R-SSC-428779 https://reactome.org/PathwayBrowser/#/R-SSC-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Sus scrofa 17925 R-SSC-429036 https://reactome.org/PathwayBrowser/#/R-SSC-429036 SLC2A9 transports Fru, Glc, urate IEA Sus scrofa 17925 R-SSC-429094 https://reactome.org/PathwayBrowser/#/R-SSC-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Sus scrofa 17925 R-SSC-429567 https://reactome.org/PathwayBrowser/#/R-SSC-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Sus scrofa 17925 R-SSC-429613 https://reactome.org/PathwayBrowser/#/R-SSC-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Sus scrofa 17925 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 17925 R-SSC-450095 https://reactome.org/PathwayBrowser/#/R-SSC-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Sus scrofa 17925 R-SSC-499981 https://reactome.org/PathwayBrowser/#/R-SSC-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Sus scrofa 17925 R-SSC-5339524 https://reactome.org/PathwayBrowser/#/R-SSC-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Sus scrofa 17925 R-SSC-5652172 https://reactome.org/PathwayBrowser/#/R-SSC-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Sus scrofa 17925 R-SSC-5653873 https://reactome.org/PathwayBrowser/#/R-SSC-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Sus scrofa 17925 R-SSC-5653878 https://reactome.org/PathwayBrowser/#/R-SSC-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Sus scrofa 17925 R-SSC-5659861 https://reactome.org/PathwayBrowser/#/R-SSC-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Sus scrofa 17925 R-SSC-5696021 https://reactome.org/PathwayBrowser/#/R-SSC-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Sus scrofa 17925 R-SSC-70420 https://reactome.org/PathwayBrowser/#/R-SSC-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Sus scrofa 17925 R-SSC-71593 https://reactome.org/PathwayBrowser/#/R-SSC-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Sus scrofa 17925 R-SSC-71825 https://reactome.org/PathwayBrowser/#/R-SSC-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Sus scrofa 17925 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 17925 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 17925 R-SSC-8875902 https://reactome.org/PathwayBrowser/#/R-SSC-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Sus scrofa 17925 R-SSC-8876319 https://reactome.org/PathwayBrowser/#/R-SSC-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Sus scrofa 17925 R-SSC-8932955 https://reactome.org/PathwayBrowser/#/R-SSC-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Sus scrofa 17925 R-SSC-8981553 https://reactome.org/PathwayBrowser/#/R-SSC-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Sus scrofa 17925 R-SSC-8981564 https://reactome.org/PathwayBrowser/#/R-SSC-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Sus scrofa 17925 R-SSC-8981570 https://reactome.org/PathwayBrowser/#/R-SSC-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Sus scrofa 17925 R-SSC-8981574 https://reactome.org/PathwayBrowser/#/R-SSC-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Sus scrofa 17925 R-SSC-9036727 https://reactome.org/PathwayBrowser/#/R-SSC-9036727 GAA hydrolyzes lysosomal glycogen IEA Sus scrofa 17925 R-SSC-964759 https://reactome.org/PathwayBrowser/#/R-SSC-964759 Alternative endo-mannosidase I route IEA Sus scrofa 17925 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 17925 R-XTR-170810 https://reactome.org/PathwayBrowser/#/R-XTR-170810 nucleoplasmic GCK1:GKRP complex => glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Xenopus tropicalis 17925 R-XTR-188979 https://reactome.org/PathwayBrowser/#/R-XTR-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Xenopus tropicalis 17925 R-XTR-189062 https://reactome.org/PathwayBrowser/#/R-XTR-189062 lactose + H2O => D-glucose + D-galactose IEA Xenopus tropicalis 17925 R-XTR-189208 https://reactome.org/PathwayBrowser/#/R-XTR-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Xenopus tropicalis 17925 R-XTR-189242 https://reactome.org/PathwayBrowser/#/R-XTR-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Xenopus tropicalis 17925 R-XTR-191114 https://reactome.org/PathwayBrowser/#/R-XTR-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Xenopus tropicalis 17925 R-XTR-265682 https://reactome.org/PathwayBrowser/#/R-XTR-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Xenopus tropicalis 17925 R-XTR-383313 https://reactome.org/PathwayBrowser/#/R-XTR-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Xenopus tropicalis 17925 R-XTR-428779 https://reactome.org/PathwayBrowser/#/R-XTR-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Xenopus tropicalis 17925 R-XTR-429036 https://reactome.org/PathwayBrowser/#/R-XTR-429036 SLC2A9 transports Fru, Glc, urate IEA Xenopus tropicalis 17925 R-XTR-429094 https://reactome.org/PathwayBrowser/#/R-XTR-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Xenopus tropicalis 17925 R-XTR-429613 https://reactome.org/PathwayBrowser/#/R-XTR-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 17925 R-XTR-450095 https://reactome.org/PathwayBrowser/#/R-XTR-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Xenopus tropicalis 17925 R-XTR-499981 https://reactome.org/PathwayBrowser/#/R-XTR-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Xenopus tropicalis 17925 R-XTR-5339524 https://reactome.org/PathwayBrowser/#/R-XTR-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 17925 R-XTR-5652172 https://reactome.org/PathwayBrowser/#/R-XTR-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Xenopus tropicalis 17925 R-XTR-5653873 https://reactome.org/PathwayBrowser/#/R-XTR-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Xenopus tropicalis 17925 R-XTR-5653878 https://reactome.org/PathwayBrowser/#/R-XTR-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Xenopus tropicalis 17925 R-XTR-5696021 https://reactome.org/PathwayBrowser/#/R-XTR-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Xenopus tropicalis 17925 R-XTR-70420 https://reactome.org/PathwayBrowser/#/R-XTR-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Xenopus tropicalis 17925 R-XTR-71593 https://reactome.org/PathwayBrowser/#/R-XTR-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Xenopus tropicalis 17925 R-XTR-71825 https://reactome.org/PathwayBrowser/#/R-XTR-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Xenopus tropicalis 17925 R-XTR-8875902 https://reactome.org/PathwayBrowser/#/R-XTR-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 17925 R-XTR-8876319 https://reactome.org/PathwayBrowser/#/R-XTR-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Xenopus tropicalis 17925 R-XTR-8932955 https://reactome.org/PathwayBrowser/#/R-XTR-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Xenopus tropicalis 17925 R-XTR-8981553 https://reactome.org/PathwayBrowser/#/R-XTR-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 17925 R-XTR-8981564 https://reactome.org/PathwayBrowser/#/R-XTR-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 17925 R-XTR-8981570 https://reactome.org/PathwayBrowser/#/R-XTR-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 17925 R-XTR-8981574 https://reactome.org/PathwayBrowser/#/R-XTR-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 17925 R-XTR-964759 https://reactome.org/PathwayBrowser/#/R-XTR-964759 Alternative endo-mannosidase I route IEA Xenopus tropicalis 17927 R-BTA-141348 https://reactome.org/PathwayBrowser/#/R-BTA-141348 PAO:FAD oxidises NASPM to PTCN IEA Bos taurus 17927 R-BTA-351208 https://reactome.org/PathwayBrowser/#/R-BTA-351208 Spermidine => N-acetylated spermidine IEA Bos taurus 17927 R-CEL-141348 https://reactome.org/PathwayBrowser/#/R-CEL-141348 PAO:FAD oxidises NASPM to PTCN IEA Caenorhabditis elegans 17927 R-CEL-351208 https://reactome.org/PathwayBrowser/#/R-CEL-351208 Spermidine => N-acetylated spermidine IEA Caenorhabditis elegans 17927 R-CFA-141348 https://reactome.org/PathwayBrowser/#/R-CFA-141348 PAO:FAD oxidises NASPM to PTCN IEA Canis familiaris 17927 R-CFA-351208 https://reactome.org/PathwayBrowser/#/R-CFA-351208 Spermidine => N-acetylated spermidine IEA Canis familiaris 17927 R-DDI-351208 https://reactome.org/PathwayBrowser/#/R-DDI-351208 Spermidine => N-acetylated spermidine IEA Dictyostelium discoideum 17927 R-DME-141348 https://reactome.org/PathwayBrowser/#/R-DME-141348 PAO:FAD oxidises NASPM to PTCN IEA Drosophila melanogaster 17927 R-DME-351208 https://reactome.org/PathwayBrowser/#/R-DME-351208 Spermidine => N-acetylated spermidine IEA Drosophila melanogaster 17927 R-DRE-141348 https://reactome.org/PathwayBrowser/#/R-DRE-141348 PAO:FAD oxidises NASPM to PTCN IEA Danio rerio 17927 R-DRE-351208 https://reactome.org/PathwayBrowser/#/R-DRE-351208 Spermidine => N-acetylated spermidine IEA Danio rerio 17927 R-GGA-141348 https://reactome.org/PathwayBrowser/#/R-GGA-141348 PAO:FAD oxidises NASPM to PTCN IEA Gallus gallus 17927 R-GGA-351208 https://reactome.org/PathwayBrowser/#/R-GGA-351208 Spermidine => N-acetylated spermidine IEA Gallus gallus 17927 R-HSA-141348 https://reactome.org/PathwayBrowser/#/R-HSA-141348 PAO:FAD oxidises NASPM to PTCN TAS Homo sapiens 17927 R-HSA-351201 https://reactome.org/PathwayBrowser/#/R-HSA-351201 N-acetylated spermidine (cytosol)=>N-acetylated spermidine (peroxisomal) TAS Homo sapiens 17927 R-HSA-351208 https://reactome.org/PathwayBrowser/#/R-HSA-351208 Spermidine => N-acetylated spermidine TAS Homo sapiens 17927 R-MMU-141348 https://reactome.org/PathwayBrowser/#/R-MMU-141348 PAO:FAD oxidises NASPM to PTCN IEA Mus musculus 17927 R-MMU-351208 https://reactome.org/PathwayBrowser/#/R-MMU-351208 Spermidine => N-acetylated spermidine IEA Mus musculus 17927 R-RNO-141348 https://reactome.org/PathwayBrowser/#/R-RNO-141348 PAO:FAD oxidises NASPM to PTCN IEA Rattus norvegicus 17927 R-RNO-351208 https://reactome.org/PathwayBrowser/#/R-RNO-351208 Spermidine => N-acetylated spermidine IEA Rattus norvegicus 17927 R-SCE-351208 https://reactome.org/PathwayBrowser/#/R-SCE-351208 Spermidine => N-acetylated spermidine IEA Saccharomyces cerevisiae 17927 R-SPO-351208 https://reactome.org/PathwayBrowser/#/R-SPO-351208 Spermidine => N-acetylated spermidine IEA Schizosaccharomyces pombe 17927 R-SSC-141348 https://reactome.org/PathwayBrowser/#/R-SSC-141348 PAO:FAD oxidises NASPM to PTCN IEA Sus scrofa 17927 R-SSC-351208 https://reactome.org/PathwayBrowser/#/R-SSC-351208 Spermidine => N-acetylated spermidine IEA Sus scrofa 17927 R-XTR-351208 https://reactome.org/PathwayBrowser/#/R-XTR-351208 Spermidine => N-acetylated spermidine IEA Xenopus tropicalis 17931 R-BTA-176669 https://reactome.org/PathwayBrowser/#/R-BTA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Bos taurus 17931 R-CFA-176669 https://reactome.org/PathwayBrowser/#/R-CFA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Canis familiaris 17931 R-DME-176669 https://reactome.org/PathwayBrowser/#/R-DME-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Drosophila melanogaster 17931 R-DRE-176669 https://reactome.org/PathwayBrowser/#/R-DRE-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Danio rerio 17931 R-GGA-176669 https://reactome.org/PathwayBrowser/#/R-GGA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Gallus gallus 17931 R-HSA-176669 https://reactome.org/PathwayBrowser/#/R-HSA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP TAS Homo sapiens 17931 R-MMU-176669 https://reactome.org/PathwayBrowser/#/R-MMU-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Mus musculus 17931 R-RNO-176669 https://reactome.org/PathwayBrowser/#/R-RNO-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Rattus norvegicus 17931 R-SSC-176669 https://reactome.org/PathwayBrowser/#/R-SSC-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Sus scrofa 17931 R-XTR-176669 https://reactome.org/PathwayBrowser/#/R-XTR-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Xenopus tropicalis 17933 R-BTA-209760 https://reactome.org/PathwayBrowser/#/R-BTA-209760 Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen IEA Bos taurus 17933 R-BTA-209845 https://reactome.org/PathwayBrowser/#/R-BTA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Bos taurus 17933 R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 17933 R-BTA-209944 https://reactome.org/PathwayBrowser/#/R-BTA-209944 25(OH)D binds GC IEA Bos taurus 17933 R-BTA-350158 https://reactome.org/PathwayBrowser/#/R-BTA-350158 LGMN degrades GC IEA Bos taurus 17933 R-BTA-350168 https://reactome.org/PathwayBrowser/#/R-BTA-350168 LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D IEA Bos taurus 17933 R-BTA-350186 https://reactome.org/PathwayBrowser/#/R-BTA-350186 CUBN binds GC:25(OH)D IEA Bos taurus 17933 R-BTA-8963864 https://reactome.org/PathwayBrowser/#/R-BTA-8963864 CUBN dissociates from 25(OH)D IEA Bos taurus 17933 R-CEL-209845 https://reactome.org/PathwayBrowser/#/R-CEL-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Caenorhabditis elegans 17933 R-CEL-8963864 https://reactome.org/PathwayBrowser/#/R-CEL-8963864 CUBN dissociates from 25(OH)D IEA Caenorhabditis elegans 17933 R-CFA-209845 https://reactome.org/PathwayBrowser/#/R-CFA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Canis familiaris 17933 R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 17933 R-CFA-209944 https://reactome.org/PathwayBrowser/#/R-CFA-209944 25(OH)D binds GC IEA Canis familiaris 17933 R-DDI-209845 https://reactome.org/PathwayBrowser/#/R-DDI-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Dictyostelium discoideum 17933 R-DME-209845 https://reactome.org/PathwayBrowser/#/R-DME-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Drosophila melanogaster 17933 R-DME-8963864 https://reactome.org/PathwayBrowser/#/R-DME-8963864 CUBN dissociates from 25(OH)D IEA Drosophila melanogaster 17933 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 17933 R-GGA-209845 https://reactome.org/PathwayBrowser/#/R-GGA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Gallus gallus 17933 R-GGA-209944 https://reactome.org/PathwayBrowser/#/R-GGA-209944 25(OH)D binds GC IEA Gallus gallus 17933 R-HSA-209760 https://reactome.org/PathwayBrowser/#/R-HSA-209760 Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen TAS Homo sapiens 17933 R-HSA-209766 https://reactome.org/PathwayBrowser/#/R-HSA-209766 25(OH)D translocates from lysosomal lumen to cytosol TAS Homo sapiens 17933 R-HSA-209845 https://reactome.org/PathwayBrowser/#/R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D TAS Homo sapiens 17933 R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 17933 R-HSA-209944 https://reactome.org/PathwayBrowser/#/R-HSA-209944 25(OH)D binds GC TAS Homo sapiens 17933 R-HSA-350158 https://reactome.org/PathwayBrowser/#/R-HSA-350158 LGMN degrades GC TAS Homo sapiens 17933 R-HSA-350168 https://reactome.org/PathwayBrowser/#/R-HSA-350168 LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D TAS Homo sapiens 17933 R-HSA-350186 https://reactome.org/PathwayBrowser/#/R-HSA-350186 CUBN binds GC:25(OH)D TAS Homo sapiens 17933 R-HSA-5602186 https://reactome.org/PathwayBrowser/#/R-HSA-5602186 Defective CYP27B1 does not hydroxylate CDL TAS Homo sapiens 17933 R-HSA-6807242 https://reactome.org/PathwayBrowser/#/R-HSA-6807242 25(OH)D translocates from ER membrane to extracellular region TAS Homo sapiens 17933 R-HSA-8963864 https://reactome.org/PathwayBrowser/#/R-HSA-8963864 CUBN dissociates from 25(OH)D TAS Homo sapiens 17933 R-MMU-209845 https://reactome.org/PathwayBrowser/#/R-MMU-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Mus musculus 17933 R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 17933 R-MMU-209944 https://reactome.org/PathwayBrowser/#/R-MMU-209944 25(OH)D binds GC IEA Mus musculus 17933 R-RNO-209760 https://reactome.org/PathwayBrowser/#/R-RNO-209760 Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen IEA Rattus norvegicus 17933 R-RNO-209845 https://reactome.org/PathwayBrowser/#/R-RNO-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Rattus norvegicus 17933 R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 17933 R-RNO-209944 https://reactome.org/PathwayBrowser/#/R-RNO-209944 25(OH)D binds GC IEA Rattus norvegicus 17933 R-RNO-350158 https://reactome.org/PathwayBrowser/#/R-RNO-350158 LGMN degrades GC IEA Rattus norvegicus 17933 R-RNO-350168 https://reactome.org/PathwayBrowser/#/R-RNO-350168 LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D IEA Rattus norvegicus 17933 R-RNO-350186 https://reactome.org/PathwayBrowser/#/R-RNO-350186 CUBN binds GC:25(OH)D IEA Rattus norvegicus 17933 R-RNO-8963864 https://reactome.org/PathwayBrowser/#/R-RNO-8963864 CUBN dissociates from 25(OH)D IEA Rattus norvegicus 17933 R-SSC-209845 https://reactome.org/PathwayBrowser/#/R-SSC-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Sus scrofa 17933 R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 17933 R-SSC-209944 https://reactome.org/PathwayBrowser/#/R-SSC-209944 25(OH)D binds GC IEA Sus scrofa 17933 R-XTR-209845 https://reactome.org/PathwayBrowser/#/R-XTR-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Xenopus tropicalis 17933 R-XTR-209944 https://reactome.org/PathwayBrowser/#/R-XTR-209944 25(OH)D binds GC IEA Xenopus tropicalis 17936 R-BTA-6792445 https://reactome.org/PathwayBrowser/#/R-BTA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Bos taurus 17936 R-CFA-6792445 https://reactome.org/PathwayBrowser/#/R-CFA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Canis familiaris 17936 R-DME-6792445 https://reactome.org/PathwayBrowser/#/R-DME-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Drosophila melanogaster 17936 R-DRE-6792445 https://reactome.org/PathwayBrowser/#/R-DRE-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Danio rerio 17936 R-GGA-6792445 https://reactome.org/PathwayBrowser/#/R-GGA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Gallus gallus 17936 R-HSA-6792445 https://reactome.org/PathwayBrowser/#/R-HSA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA TAS Homo sapiens 17936 R-MMU-6792445 https://reactome.org/PathwayBrowser/#/R-MMU-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Mus musculus 17936 R-RNO-6792445 https://reactome.org/PathwayBrowser/#/R-RNO-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Rattus norvegicus 17936 R-SSC-6792445 https://reactome.org/PathwayBrowser/#/R-SSC-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Sus scrofa 17936 R-XTR-6792445 https://reactome.org/PathwayBrowser/#/R-XTR-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Xenopus tropicalis 17950 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 17950 R-BTA-9844587 https://reactome.org/PathwayBrowser/#/R-BTA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Bos taurus 17950 R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 17950 R-BTA-9846477 https://reactome.org/PathwayBrowser/#/R-BTA-9846477 A4GALT transfers galactose to LacCer IEA Bos taurus 17950 R-BTA-9846501 https://reactome.org/PathwayBrowser/#/R-BTA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Bos taurus 17950 R-BTA-9851347 https://reactome.org/PathwayBrowser/#/R-BTA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Bos taurus 17950 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 17950 R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 17950 R-CFA-9846477 https://reactome.org/PathwayBrowser/#/R-CFA-9846477 A4GALT transfers galactose to LacCer IEA Canis familiaris 17950 R-CFA-9851347 https://reactome.org/PathwayBrowser/#/R-CFA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Canis familiaris 17950 R-DME-9846477 https://reactome.org/PathwayBrowser/#/R-DME-9846477 A4GALT transfers galactose to LacCer IEA Drosophila melanogaster 17950 R-DME-9846501 https://reactome.org/PathwayBrowser/#/R-DME-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Drosophila melanogaster 17950 R-DME-9851347 https://reactome.org/PathwayBrowser/#/R-DME-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Drosophila melanogaster 17950 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 17950 R-DRE-9844587 https://reactome.org/PathwayBrowser/#/R-DRE-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Danio rerio 17950 R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 17950 R-DRE-9846501 https://reactome.org/PathwayBrowser/#/R-DRE-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Danio rerio 17950 R-DRE-9851347 https://reactome.org/PathwayBrowser/#/R-DRE-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Danio rerio 17950 R-GGA-9844587 https://reactome.org/PathwayBrowser/#/R-GGA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Gallus gallus 17950 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 17950 R-GGA-9846477 https://reactome.org/PathwayBrowser/#/R-GGA-9846477 A4GALT transfers galactose to LacCer IEA Gallus gallus 17950 R-GGA-9846501 https://reactome.org/PathwayBrowser/#/R-GGA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Gallus gallus 17950 R-GGA-9851347 https://reactome.org/PathwayBrowser/#/R-GGA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Gallus gallus 17950 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 17950 R-HSA-9844587 https://reactome.org/PathwayBrowser/#/R-HSA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer TAS Homo sapiens 17950 R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 17950 R-HSA-9846477 https://reactome.org/PathwayBrowser/#/R-HSA-9846477 A4GALT transfers galactose to LacCer TAS Homo sapiens 17950 R-HSA-9846501 https://reactome.org/PathwayBrowser/#/R-HSA-9846501 B3GNT5 transfers GlcNAc to LacCer TAS Homo sapiens 17950 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 17950 R-HSA-9851347 https://reactome.org/PathwayBrowser/#/R-HSA-9851347 B4GALT5/6 transfer Gal to GlcCer TAS Homo sapiens 17950 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 17950 R-MMU-9844587 https://reactome.org/PathwayBrowser/#/R-MMU-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Mus musculus 17950 R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 17950 R-MMU-9846477 https://reactome.org/PathwayBrowser/#/R-MMU-9846477 A4GALT transfers galactose to LacCer IEA Mus musculus 17950 R-MMU-9846501 https://reactome.org/PathwayBrowser/#/R-MMU-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Mus musculus 17950 R-MMU-9851347 https://reactome.org/PathwayBrowser/#/R-MMU-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Mus musculus 17950 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 17950 R-RNO-9844587 https://reactome.org/PathwayBrowser/#/R-RNO-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Rattus norvegicus 17950 R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 17950 R-RNO-9846477 https://reactome.org/PathwayBrowser/#/R-RNO-9846477 A4GALT transfers galactose to LacCer IEA Rattus norvegicus 17950 R-RNO-9846501 https://reactome.org/PathwayBrowser/#/R-RNO-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Rattus norvegicus 17950 R-RNO-9851347 https://reactome.org/PathwayBrowser/#/R-RNO-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Rattus norvegicus 17950 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 17950 R-SSC-9844587 https://reactome.org/PathwayBrowser/#/R-SSC-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Sus scrofa 17950 R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 17950 R-SSC-9846477 https://reactome.org/PathwayBrowser/#/R-SSC-9846477 A4GALT transfers galactose to LacCer IEA Sus scrofa 17950 R-SSC-9846501 https://reactome.org/PathwayBrowser/#/R-SSC-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Sus scrofa 17950 R-SSC-9851347 https://reactome.org/PathwayBrowser/#/R-SSC-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Sus scrofa 17950 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 17950 R-XTR-9844587 https://reactome.org/PathwayBrowser/#/R-XTR-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Xenopus tropicalis 17950 R-XTR-9846501 https://reactome.org/PathwayBrowser/#/R-XTR-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Xenopus tropicalis 17950 R-XTR-9851347 https://reactome.org/PathwayBrowser/#/R-XTR-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Xenopus tropicalis 17968 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 17968 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Bos taurus 17968 R-BTA-444047 https://reactome.org/PathwayBrowser/#/R-BTA-444047 Receptor FFAR3 binds carboxylates IEA Bos taurus 17968 R-BTA-444171 https://reactome.org/PathwayBrowser/#/R-BTA-444171 Receptor FFAR2 binds carboxylates IEA Bos taurus 17968 R-BTA-5695964 https://reactome.org/PathwayBrowser/#/R-BTA-5695964 ABHD14B hydrolyses PNPB IEA Bos taurus 17968 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 17968 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 17968 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 17968 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Caenorhabditis elegans 17968 R-CEL-5695964 https://reactome.org/PathwayBrowser/#/R-CEL-5695964 ABHD14B hydrolyses PNPB IEA Caenorhabditis elegans 17968 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 17968 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 17968 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Canis familiaris 17968 R-CFA-444047 https://reactome.org/PathwayBrowser/#/R-CFA-444047 Receptor FFAR3 binds carboxylates IEA Canis familiaris 17968 R-CFA-444171 https://reactome.org/PathwayBrowser/#/R-CFA-444171 Receptor FFAR2 binds carboxylates IEA Canis familiaris 17968 R-CFA-5695964 https://reactome.org/PathwayBrowser/#/R-CFA-5695964 ABHD14B hydrolyses PNPB IEA Canis familiaris 17968 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 17968 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 17968 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 17968 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Drosophila melanogaster 17968 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 17968 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 17968 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Danio rerio 17968 R-DRE-444047 https://reactome.org/PathwayBrowser/#/R-DRE-444047 Receptor FFAR3 binds carboxylates IEA Danio rerio 17968 R-DRE-444171 https://reactome.org/PathwayBrowser/#/R-DRE-444171 Receptor FFAR2 binds carboxylates IEA Danio rerio 17968 R-DRE-5695964 https://reactome.org/PathwayBrowser/#/R-DRE-5695964 ABHD14B hydrolyses PNPB IEA Danio rerio 17968 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 17968 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 17968 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Gallus gallus 17968 R-GGA-444171 https://reactome.org/PathwayBrowser/#/R-GGA-444171 Receptor FFAR2 binds carboxylates IEA Gallus gallus 17968 R-GGA-5695964 https://reactome.org/PathwayBrowser/#/R-GGA-5695964 ABHD14B hydrolyses PNPB IEA Gallus gallus 17968 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 17968 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 17968 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 17968 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 17968 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol TAS Homo sapiens 17968 R-HSA-444047 https://reactome.org/PathwayBrowser/#/R-HSA-444047 Receptor FFAR3 binds carboxylates TAS Homo sapiens 17968 R-HSA-444171 https://reactome.org/PathwayBrowser/#/R-HSA-444171 Receptor FFAR2 binds carboxylates TAS Homo sapiens 17968 R-HSA-5695964 https://reactome.org/PathwayBrowser/#/R-HSA-5695964 ABHD14B hydrolyses PNPB TAS Homo sapiens 17968 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 17968 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 17968 R-HSA-8875013 https://reactome.org/PathwayBrowser/#/R-HSA-8875013 ACSM3,ACSM6 ligate CoA to BUT IEA Homo sapiens 17968 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 17968 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 17968 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 17968 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 17968 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Mus musculus 17968 R-MMU-444047 https://reactome.org/PathwayBrowser/#/R-MMU-444047 Receptor FFAR3 binds carboxylates IEA Mus musculus 17968 R-MMU-444171 https://reactome.org/PathwayBrowser/#/R-MMU-444171 Receptor FFAR2 binds carboxylates IEA Mus musculus 17968 R-MMU-5695964 https://reactome.org/PathwayBrowser/#/R-MMU-5695964 ABHD14B hydrolyses PNPB IEA Mus musculus 17968 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 17968 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 17968 R-MMU-8875039 https://reactome.org/PathwayBrowser/#/R-MMU-8875039 Acsm3 ligates CoA to BUT TAS Mus musculus 17968 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 17968 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 17968 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Rattus norvegicus 17968 R-RNO-444047 https://reactome.org/PathwayBrowser/#/R-RNO-444047 Receptor FFAR3 binds carboxylates IEA Rattus norvegicus 17968 R-RNO-444171 https://reactome.org/PathwayBrowser/#/R-RNO-444171 Receptor FFAR2 binds carboxylates IEA Rattus norvegicus 17968 R-RNO-5695964 https://reactome.org/PathwayBrowser/#/R-RNO-5695964 ABHD14B hydrolyses PNPB IEA Rattus norvegicus 17968 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 17968 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Sus scrofa 17968 R-SSC-444047 https://reactome.org/PathwayBrowser/#/R-SSC-444047 Receptor FFAR3 binds carboxylates IEA Sus scrofa 17968 R-SSC-444171 https://reactome.org/PathwayBrowser/#/R-SSC-444171 Receptor FFAR2 binds carboxylates IEA Sus scrofa 17968 R-SSC-5695964 https://reactome.org/PathwayBrowser/#/R-SSC-5695964 ABHD14B hydrolyses PNPB IEA Sus scrofa 17968 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 17968 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 17968 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 17968 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Xenopus tropicalis 17968 R-XTR-444171 https://reactome.org/PathwayBrowser/#/R-XTR-444171 Receptor FFAR2 binds carboxylates IEA Xenopus tropicalis 17968 R-XTR-5695964 https://reactome.org/PathwayBrowser/#/R-XTR-5695964 ABHD14B hydrolyses PNPB IEA Xenopus tropicalis 17968 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 17968 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 17972 R-BTA-6781824 https://reactome.org/PathwayBrowser/#/R-BTA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Bos taurus 17972 R-CEL-6781824 https://reactome.org/PathwayBrowser/#/R-CEL-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Caenorhabditis elegans 17972 R-CFA-6781824 https://reactome.org/PathwayBrowser/#/R-CFA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Canis familiaris 17972 R-DDI-6781824 https://reactome.org/PathwayBrowser/#/R-DDI-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Dictyostelium discoideum 17972 R-DME-6781824 https://reactome.org/PathwayBrowser/#/R-DME-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Drosophila melanogaster 17972 R-GGA-6781824 https://reactome.org/PathwayBrowser/#/R-GGA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Gallus gallus 17972 R-HSA-6781824 https://reactome.org/PathwayBrowser/#/R-HSA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template TAS Homo sapiens 17972 R-MMU-6781824 https://reactome.org/PathwayBrowser/#/R-MMU-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Mus musculus 17972 R-PFA-6781824 https://reactome.org/PathwayBrowser/#/R-PFA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Plasmodium falciparum 17972 R-RNO-6781824 https://reactome.org/PathwayBrowser/#/R-RNO-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Rattus norvegicus 17972 R-SCE-6781824 https://reactome.org/PathwayBrowser/#/R-SCE-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Saccharomyces cerevisiae 17972 R-SPO-6781824 https://reactome.org/PathwayBrowser/#/R-SPO-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Schizosaccharomyces pombe 17972 R-SSC-6781824 https://reactome.org/PathwayBrowser/#/R-SSC-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Sus scrofa 17972 R-XTR-6781824 https://reactome.org/PathwayBrowser/#/R-XTR-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Xenopus tropicalis 17973 R-BTA-70355 https://reactome.org/PathwayBrowser/#/R-BTA-70355 GALK1 phosphorylates Gal to Gal1P IEA Bos taurus 17973 R-BTA-70361 https://reactome.org/PathwayBrowser/#/R-BTA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Bos taurus 17973 R-CEL-70361 https://reactome.org/PathwayBrowser/#/R-CEL-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Caenorhabditis elegans 17973 R-CFA-70355 https://reactome.org/PathwayBrowser/#/R-CFA-70355 GALK1 phosphorylates Gal to Gal1P IEA Canis familiaris 17973 R-CFA-70361 https://reactome.org/PathwayBrowser/#/R-CFA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Canis familiaris 17973 R-DME-70361 https://reactome.org/PathwayBrowser/#/R-DME-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Drosophila melanogaster 17973 R-DRE-70355 https://reactome.org/PathwayBrowser/#/R-DRE-70355 GALK1 phosphorylates Gal to Gal1P IEA Danio rerio 17973 R-GGA-70355 https://reactome.org/PathwayBrowser/#/R-GGA-70355 GALK1 phosphorylates Gal to Gal1P IEA Gallus gallus 17973 R-HSA-5610038 https://reactome.org/PathwayBrowser/#/R-HSA-5610038 Defective GALT does not transfer UMP to Gal1P TAS Homo sapiens 17973 R-HSA-70355 https://reactome.org/PathwayBrowser/#/R-HSA-70355 GALK1 phosphorylates Gal to Gal1P TAS Homo sapiens 17973 R-HSA-70361 https://reactome.org/PathwayBrowser/#/R-HSA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal TAS Homo sapiens 17973 R-MMU-70355 https://reactome.org/PathwayBrowser/#/R-MMU-70355 GALK1 phosphorylates Gal to Gal1P IEA Mus musculus 17973 R-MMU-70361 https://reactome.org/PathwayBrowser/#/R-MMU-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Mus musculus 17973 R-RNO-70355 https://reactome.org/PathwayBrowser/#/R-RNO-70355 GALK1 phosphorylates Gal to Gal1P IEA Rattus norvegicus 17973 R-RNO-70361 https://reactome.org/PathwayBrowser/#/R-RNO-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Rattus norvegicus 17973 R-SSC-70355 https://reactome.org/PathwayBrowser/#/R-SSC-70355 GALK1 phosphorylates Gal to Gal1P IEA Sus scrofa 17973 R-SSC-70361 https://reactome.org/PathwayBrowser/#/R-SSC-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Sus scrofa 17973 R-XTR-70355 https://reactome.org/PathwayBrowser/#/R-XTR-70355 GALK1 phosphorylates Gal to Gal1P IEA Xenopus tropicalis 17976 R-AMA-1614571 https://reactome.org/PathwayBrowser/#/R-AMA-1614571 Sqr oxidizes sulfide to bound persulfide TAS Arenicola marina 17976 R-BTA-163217 https://reactome.org/PathwayBrowser/#/R-BTA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Bos taurus 17976 R-BTA-164651 https://reactome.org/PathwayBrowser/#/R-BTA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Bos taurus 17976 R-BTA-73569 https://reactome.org/PathwayBrowser/#/R-BTA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Bos taurus 17976 R-CEL-164651 https://reactome.org/PathwayBrowser/#/R-CEL-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Caenorhabditis elegans 17976 R-CEL-169270 https://reactome.org/PathwayBrowser/#/R-CEL-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Caenorhabditis elegans 17976 R-CEL-73569 https://reactome.org/PathwayBrowser/#/R-CEL-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Caenorhabditis elegans 17976 R-CFA-163217 https://reactome.org/PathwayBrowser/#/R-CFA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Canis familiaris 17976 R-CFA-169270 https://reactome.org/PathwayBrowser/#/R-CFA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Canis familiaris 17976 R-CFA-73569 https://reactome.org/PathwayBrowser/#/R-CFA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Canis familiaris 17976 R-DDI-164651 https://reactome.org/PathwayBrowser/#/R-DDI-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Dictyostelium discoideum 17976 R-DDI-169270 https://reactome.org/PathwayBrowser/#/R-DDI-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Dictyostelium discoideum 17976 R-DME-163217 https://reactome.org/PathwayBrowser/#/R-DME-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Drosophila melanogaster 17976 R-DME-164651 https://reactome.org/PathwayBrowser/#/R-DME-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Drosophila melanogaster 17976 R-DME-169270 https://reactome.org/PathwayBrowser/#/R-DME-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Drosophila melanogaster 17976 R-DME-73569 https://reactome.org/PathwayBrowser/#/R-DME-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Drosophila melanogaster 17976 R-DRE-163217 https://reactome.org/PathwayBrowser/#/R-DRE-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Danio rerio 17976 R-DRE-164651 https://reactome.org/PathwayBrowser/#/R-DRE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Danio rerio 17976 R-DRE-169270 https://reactome.org/PathwayBrowser/#/R-DRE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Danio rerio 17976 R-DRE-73569 https://reactome.org/PathwayBrowser/#/R-DRE-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Danio rerio 17976 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Gallus gallus 17976 R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus 17976 R-GGA-419452 https://reactome.org/PathwayBrowser/#/R-GGA-419452 (S)-dihydroorotate + ubiquinone => orotate + ubiquinol IEA Gallus gallus 17976 R-GGA-73569 https://reactome.org/PathwayBrowser/#/R-GGA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Gallus gallus 17976 R-HSA-1614665 https://reactome.org/PathwayBrowser/#/R-HSA-1614665 SQR oxidizes sulfide to bound persulfide IEA Homo sapiens 17976 R-HSA-163213 https://reactome.org/PathwayBrowser/#/R-HSA-163213 Transfer of electrons through the succinate dehydrogenase complex IEA Homo sapiens 17976 R-HSA-163217 https://reactome.org/PathwayBrowser/#/R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 TAS Homo sapiens 17976 R-HSA-164651 https://reactome.org/PathwayBrowser/#/R-HSA-164651 Electron transfer from ubiquinol to cytochrome c of complex III TAS Homo sapiens 17976 R-HSA-169270 https://reactome.org/PathwayBrowser/#/R-HSA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 TAS Homo sapiens 17976 R-HSA-73569 https://reactome.org/PathwayBrowser/#/R-HSA-73569 DHODH:FMN oxidises (S)-DHO to orotate TAS Homo sapiens 17976 R-MMU-163217 https://reactome.org/PathwayBrowser/#/R-MMU-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Mus musculus 17976 R-MMU-164651 https://reactome.org/PathwayBrowser/#/R-MMU-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Mus musculus 17976 R-MMU-169270 https://reactome.org/PathwayBrowser/#/R-MMU-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Mus musculus 17976 R-MMU-73569 https://reactome.org/PathwayBrowser/#/R-MMU-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Mus musculus 17976 R-PFA-73569 https://reactome.org/PathwayBrowser/#/R-PFA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Plasmodium falciparum 17976 R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Rattus norvegicus 17976 R-RNO-164651 https://reactome.org/PathwayBrowser/#/R-RNO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Rattus norvegicus 17976 R-RNO-169270 https://reactome.org/PathwayBrowser/#/R-RNO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Rattus norvegicus 17976 R-RNO-73569 https://reactome.org/PathwayBrowser/#/R-RNO-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Rattus norvegicus 17976 R-SCE-164651 https://reactome.org/PathwayBrowser/#/R-SCE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Saccharomyces cerevisiae 17976 R-SCE-169270 https://reactome.org/PathwayBrowser/#/R-SCE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Saccharomyces cerevisiae 17976 R-SPO-164651 https://reactome.org/PathwayBrowser/#/R-SPO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Schizosaccharomyces pombe 17976 R-SPO-169270 https://reactome.org/PathwayBrowser/#/R-SPO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Schizosaccharomyces pombe 17976 R-SPO-73569 https://reactome.org/PathwayBrowser/#/R-SPO-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Schizosaccharomyces pombe 17976 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Sus scrofa 17976 R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa 17976 R-SSC-169270 https://reactome.org/PathwayBrowser/#/R-SSC-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Sus scrofa 17976 R-SSC-73569 https://reactome.org/PathwayBrowser/#/R-SSC-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Sus scrofa 17976 R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Xenopus tropicalis 17976 R-XTR-169270 https://reactome.org/PathwayBrowser/#/R-XTR-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Xenopus tropicalis 17976 R-XTR-73569 https://reactome.org/PathwayBrowser/#/R-XTR-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Xenopus tropicalis 17981 R-MTU-936615 https://reactome.org/PathwayBrowser/#/R-MTU-936615 acetylation of serine TAS Mycobacterium tuberculosis 17981 R-MTU-936642 https://reactome.org/PathwayBrowser/#/R-MTU-936642 deacetylation of O-acetylserine and sulfhydrylation using CysK1 TAS Mycobacterium tuberculosis 17981 R-MTU-936745 https://reactome.org/PathwayBrowser/#/R-MTU-936745 deacetylation of O-acetylserine and sulfhydrylation using CysK2 TAS Mycobacterium tuberculosis 17984 R-BTA-1482533 https://reactome.org/PathwayBrowser/#/R-BTA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Bos taurus 17984 R-BTA-1482539 https://reactome.org/PathwayBrowser/#/R-BTA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Bos taurus 17984 R-BTA-1482546 https://reactome.org/PathwayBrowser/#/R-BTA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Bos taurus 17984 R-BTA-1482547 https://reactome.org/PathwayBrowser/#/R-BTA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Bos taurus 17984 R-BTA-1482548 https://reactome.org/PathwayBrowser/#/R-BTA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Bos taurus 17984 R-BTA-1482598 https://reactome.org/PathwayBrowser/#/R-BTA-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Bos taurus 17984 R-BTA-1482626 https://reactome.org/PathwayBrowser/#/R-BTA-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Bos taurus 17984 R-BTA-1482635 https://reactome.org/PathwayBrowser/#/R-BTA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Bos taurus 17984 R-BTA-1482636 https://reactome.org/PathwayBrowser/#/R-BTA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Bos taurus 17984 R-BTA-1482646 https://reactome.org/PathwayBrowser/#/R-BTA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Bos taurus 17984 R-BTA-1482667 https://reactome.org/PathwayBrowser/#/R-BTA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Bos taurus 17984 R-BTA-1482689 https://reactome.org/PathwayBrowser/#/R-BTA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Bos taurus 17984 R-BTA-1482691 https://reactome.org/PathwayBrowser/#/R-BTA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Bos taurus 17984 R-BTA-1482695 https://reactome.org/PathwayBrowser/#/R-BTA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Bos taurus 17984 R-BTA-1482775 https://reactome.org/PathwayBrowser/#/R-BTA-1482775 MLCL is acylated to CL by HADH (IM) IEA Bos taurus 17984 R-BTA-1482861 https://reactome.org/PathwayBrowser/#/R-BTA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Bos taurus 17984 R-BTA-1482867 https://reactome.org/PathwayBrowser/#/R-BTA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Bos taurus 17984 R-BTA-1482889 https://reactome.org/PathwayBrowser/#/R-BTA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Bos taurus 17984 R-BTA-1483002 https://reactome.org/PathwayBrowser/#/R-BTA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Bos taurus 17984 R-BTA-428127 https://reactome.org/PathwayBrowser/#/R-BTA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Bos taurus 17984 R-BTA-428185 https://reactome.org/PathwayBrowser/#/R-BTA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Bos taurus 17984 R-BTA-549112 https://reactome.org/PathwayBrowser/#/R-BTA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Bos taurus 17984 R-BTA-5696424 https://reactome.org/PathwayBrowser/#/R-BTA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Bos taurus 17984 R-BTA-5696448 https://reactome.org/PathwayBrowser/#/R-BTA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Bos taurus 17984 R-BTA-6800334 https://reactome.org/PathwayBrowser/#/R-BTA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Bos taurus 17984 R-BTA-75885 https://reactome.org/PathwayBrowser/#/R-BTA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Bos taurus 17984 R-BTA-8848580 https://reactome.org/PathwayBrowser/#/R-BTA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Bos taurus 17984 R-BTA-8874745 https://reactome.org/PathwayBrowser/#/R-BTA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Bos taurus 17984 R-BTA-8876696 https://reactome.org/PathwayBrowser/#/R-BTA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Bos taurus 17984 R-CEL-1482533 https://reactome.org/PathwayBrowser/#/R-CEL-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Caenorhabditis elegans 17984 R-CEL-1482539 https://reactome.org/PathwayBrowser/#/R-CEL-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Caenorhabditis elegans 17984 R-CEL-1482546 https://reactome.org/PathwayBrowser/#/R-CEL-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Caenorhabditis elegans 17984 R-CEL-1482547 https://reactome.org/PathwayBrowser/#/R-CEL-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Caenorhabditis elegans 17984 R-CEL-1482548 https://reactome.org/PathwayBrowser/#/R-CEL-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Caenorhabditis elegans 17984 R-CEL-1482598 https://reactome.org/PathwayBrowser/#/R-CEL-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Caenorhabditis elegans 17984 R-CEL-1482626 https://reactome.org/PathwayBrowser/#/R-CEL-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Caenorhabditis elegans 17984 R-CEL-1482635 https://reactome.org/PathwayBrowser/#/R-CEL-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Caenorhabditis elegans 17984 R-CEL-1482636 https://reactome.org/PathwayBrowser/#/R-CEL-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Caenorhabditis elegans 17984 R-CEL-1482646 https://reactome.org/PathwayBrowser/#/R-CEL-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Caenorhabditis elegans 17984 R-CEL-1482667 https://reactome.org/PathwayBrowser/#/R-CEL-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Caenorhabditis elegans 17984 R-CEL-1482689 https://reactome.org/PathwayBrowser/#/R-CEL-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Caenorhabditis elegans 17984 R-CEL-1482691 https://reactome.org/PathwayBrowser/#/R-CEL-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Caenorhabditis elegans 17984 R-CEL-1482695 https://reactome.org/PathwayBrowser/#/R-CEL-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Caenorhabditis elegans 17984 R-CEL-1482775 https://reactome.org/PathwayBrowser/#/R-CEL-1482775 MLCL is acylated to CL by HADH (IM) IEA Caenorhabditis elegans 17984 R-CEL-1482861 https://reactome.org/PathwayBrowser/#/R-CEL-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Caenorhabditis elegans 17984 R-CEL-1482867 https://reactome.org/PathwayBrowser/#/R-CEL-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Caenorhabditis elegans 17984 R-CEL-1482889 https://reactome.org/PathwayBrowser/#/R-CEL-1482889 DAG is acylated to TAG by DGAT1/2 IEA Caenorhabditis elegans 17984 R-CEL-1483002 https://reactome.org/PathwayBrowser/#/R-CEL-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Caenorhabditis elegans 17984 R-CEL-428185 https://reactome.org/PathwayBrowser/#/R-CEL-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Caenorhabditis elegans 17984 R-CEL-549112 https://reactome.org/PathwayBrowser/#/R-CEL-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Caenorhabditis elegans 17984 R-CEL-5696424 https://reactome.org/PathwayBrowser/#/R-CEL-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Caenorhabditis elegans 17984 R-CEL-5696448 https://reactome.org/PathwayBrowser/#/R-CEL-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Caenorhabditis elegans 17984 R-CEL-6800334 https://reactome.org/PathwayBrowser/#/R-CEL-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Caenorhabditis elegans 17984 R-CEL-75885 https://reactome.org/PathwayBrowser/#/R-CEL-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Caenorhabditis elegans 17984 R-CEL-8848580 https://reactome.org/PathwayBrowser/#/R-CEL-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Caenorhabditis elegans 17984 R-CEL-8874745 https://reactome.org/PathwayBrowser/#/R-CEL-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Caenorhabditis elegans 17984 R-CEL-8876696 https://reactome.org/PathwayBrowser/#/R-CEL-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Caenorhabditis elegans 17984 R-CFA-1482533 https://reactome.org/PathwayBrowser/#/R-CFA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Canis familiaris 17984 R-CFA-1482539 https://reactome.org/PathwayBrowser/#/R-CFA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Canis familiaris 17984 R-CFA-1482547 https://reactome.org/PathwayBrowser/#/R-CFA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Canis familiaris 17984 R-CFA-1482548 https://reactome.org/PathwayBrowser/#/R-CFA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Canis familiaris 17984 R-CFA-1482598 https://reactome.org/PathwayBrowser/#/R-CFA-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Canis familiaris 17984 R-CFA-1482626 https://reactome.org/PathwayBrowser/#/R-CFA-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Canis familiaris 17984 R-CFA-1482635 https://reactome.org/PathwayBrowser/#/R-CFA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Canis familiaris 17984 R-CFA-1482636 https://reactome.org/PathwayBrowser/#/R-CFA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Canis familiaris 17984 R-CFA-1482646 https://reactome.org/PathwayBrowser/#/R-CFA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Canis familiaris 17984 R-CFA-1482667 https://reactome.org/PathwayBrowser/#/R-CFA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Canis familiaris 17984 R-CFA-1482691 https://reactome.org/PathwayBrowser/#/R-CFA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Canis familiaris 17984 R-CFA-1482695 https://reactome.org/PathwayBrowser/#/R-CFA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Canis familiaris 17984 R-CFA-1482775 https://reactome.org/PathwayBrowser/#/R-CFA-1482775 MLCL is acylated to CL by HADH (IM) IEA Canis familiaris 17984 R-CFA-1482861 https://reactome.org/PathwayBrowser/#/R-CFA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Canis familiaris 17984 R-CFA-1482867 https://reactome.org/PathwayBrowser/#/R-CFA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Canis familiaris 17984 R-CFA-1482889 https://reactome.org/PathwayBrowser/#/R-CFA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Canis familiaris 17984 R-CFA-1483002 https://reactome.org/PathwayBrowser/#/R-CFA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Canis familiaris 17984 R-CFA-428127 https://reactome.org/PathwayBrowser/#/R-CFA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Canis familiaris 17984 R-CFA-428185 https://reactome.org/PathwayBrowser/#/R-CFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Canis familiaris 17984 R-CFA-549112 https://reactome.org/PathwayBrowser/#/R-CFA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Canis familiaris 17984 R-CFA-5696424 https://reactome.org/PathwayBrowser/#/R-CFA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Canis familiaris 17984 R-CFA-5696448 https://reactome.org/PathwayBrowser/#/R-CFA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Canis familiaris 17984 R-CFA-6800334 https://reactome.org/PathwayBrowser/#/R-CFA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Canis familiaris 17984 R-CFA-75885 https://reactome.org/PathwayBrowser/#/R-CFA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Canis familiaris 17984 R-CFA-8874745 https://reactome.org/PathwayBrowser/#/R-CFA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Canis familiaris 17984 R-CFA-8876696 https://reactome.org/PathwayBrowser/#/R-CFA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Canis familiaris 17984 R-DDI-1482533 https://reactome.org/PathwayBrowser/#/R-DDI-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Dictyostelium discoideum 17984 R-DDI-1482539 https://reactome.org/PathwayBrowser/#/R-DDI-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Dictyostelium discoideum 17984 R-DDI-1482547 https://reactome.org/PathwayBrowser/#/R-DDI-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Dictyostelium discoideum 17984 R-DDI-1482548 https://reactome.org/PathwayBrowser/#/R-DDI-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Dictyostelium discoideum 17984 R-DDI-1482598 https://reactome.org/PathwayBrowser/#/R-DDI-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Dictyostelium discoideum 17984 R-DDI-1482626 https://reactome.org/PathwayBrowser/#/R-DDI-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Dictyostelium discoideum 17984 R-DDI-1482635 https://reactome.org/PathwayBrowser/#/R-DDI-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Dictyostelium discoideum 17984 R-DDI-1482636 https://reactome.org/PathwayBrowser/#/R-DDI-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Dictyostelium discoideum 17984 R-DDI-1482646 https://reactome.org/PathwayBrowser/#/R-DDI-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Dictyostelium discoideum 17984 R-DDI-1482667 https://reactome.org/PathwayBrowser/#/R-DDI-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Dictyostelium discoideum 17984 R-DDI-1482691 https://reactome.org/PathwayBrowser/#/R-DDI-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Dictyostelium discoideum 17984 R-DDI-1482861 https://reactome.org/PathwayBrowser/#/R-DDI-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Dictyostelium discoideum 17984 R-DDI-1482867 https://reactome.org/PathwayBrowser/#/R-DDI-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Dictyostelium discoideum 17984 R-DDI-1482889 https://reactome.org/PathwayBrowser/#/R-DDI-1482889 DAG is acylated to TAG by DGAT1/2 IEA Dictyostelium discoideum 17984 R-DDI-428185 https://reactome.org/PathwayBrowser/#/R-DDI-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Dictyostelium discoideum 17984 R-DDI-549112 https://reactome.org/PathwayBrowser/#/R-DDI-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Dictyostelium discoideum 17984 R-DDI-5696424 https://reactome.org/PathwayBrowser/#/R-DDI-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Dictyostelium discoideum 17984 R-DDI-5696448 https://reactome.org/PathwayBrowser/#/R-DDI-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Dictyostelium discoideum 17984 R-DDI-6800334 https://reactome.org/PathwayBrowser/#/R-DDI-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Dictyostelium discoideum 17984 R-DDI-75885 https://reactome.org/PathwayBrowser/#/R-DDI-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Dictyostelium discoideum 17984 R-DDI-8848580 https://reactome.org/PathwayBrowser/#/R-DDI-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Dictyostelium discoideum 17984 R-DME-1482533 https://reactome.org/PathwayBrowser/#/R-DME-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Drosophila melanogaster 17984 R-DME-1482539 https://reactome.org/PathwayBrowser/#/R-DME-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Drosophila melanogaster 17984 R-DME-1482546 https://reactome.org/PathwayBrowser/#/R-DME-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Drosophila melanogaster 17984 R-DME-1482547 https://reactome.org/PathwayBrowser/#/R-DME-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Drosophila melanogaster 17984 R-DME-1482598 https://reactome.org/PathwayBrowser/#/R-DME-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Drosophila melanogaster 17984 R-DME-1482626 https://reactome.org/PathwayBrowser/#/R-DME-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Drosophila melanogaster 17984 R-DME-1482635 https://reactome.org/PathwayBrowser/#/R-DME-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Drosophila melanogaster 17984 R-DME-1482636 https://reactome.org/PathwayBrowser/#/R-DME-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Drosophila melanogaster 17984 R-DME-1482646 https://reactome.org/PathwayBrowser/#/R-DME-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Drosophila melanogaster 17984 R-DME-1482667 https://reactome.org/PathwayBrowser/#/R-DME-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Drosophila melanogaster 17984 R-DME-1482689 https://reactome.org/PathwayBrowser/#/R-DME-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Drosophila melanogaster 17984 R-DME-1482691 https://reactome.org/PathwayBrowser/#/R-DME-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Drosophila melanogaster 17984 R-DME-1482695 https://reactome.org/PathwayBrowser/#/R-DME-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Drosophila melanogaster 17984 R-DME-1482775 https://reactome.org/PathwayBrowser/#/R-DME-1482775 MLCL is acylated to CL by HADH (IM) IEA Drosophila melanogaster 17984 R-DME-1482889 https://reactome.org/PathwayBrowser/#/R-DME-1482889 DAG is acylated to TAG by DGAT1/2 IEA Drosophila melanogaster 17984 R-DME-1483002 https://reactome.org/PathwayBrowser/#/R-DME-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Drosophila melanogaster 17984 R-DME-428127 https://reactome.org/PathwayBrowser/#/R-DME-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Drosophila melanogaster 17984 R-DME-428185 https://reactome.org/PathwayBrowser/#/R-DME-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Drosophila melanogaster 17984 R-DME-549112 https://reactome.org/PathwayBrowser/#/R-DME-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Drosophila melanogaster 17984 R-DME-5696424 https://reactome.org/PathwayBrowser/#/R-DME-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Drosophila melanogaster 17984 R-DME-5696448 https://reactome.org/PathwayBrowser/#/R-DME-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Drosophila melanogaster 17984 R-DME-6800334 https://reactome.org/PathwayBrowser/#/R-DME-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Drosophila melanogaster 17984 R-DME-75885 https://reactome.org/PathwayBrowser/#/R-DME-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Drosophila melanogaster 17984 R-DME-8848580 https://reactome.org/PathwayBrowser/#/R-DME-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Drosophila melanogaster 17984 R-DME-8874745 https://reactome.org/PathwayBrowser/#/R-DME-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Drosophila melanogaster 17984 R-DME-8876696 https://reactome.org/PathwayBrowser/#/R-DME-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Drosophila melanogaster 17984 R-DRE-1482533 https://reactome.org/PathwayBrowser/#/R-DRE-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Danio rerio 17984 R-DRE-1482539 https://reactome.org/PathwayBrowser/#/R-DRE-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Danio rerio 17984 R-DRE-1482546 https://reactome.org/PathwayBrowser/#/R-DRE-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Danio rerio 17984 R-DRE-1482547 https://reactome.org/PathwayBrowser/#/R-DRE-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Danio rerio 17984 R-DRE-1482598 https://reactome.org/PathwayBrowser/#/R-DRE-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Danio rerio 17984 R-DRE-1482626 https://reactome.org/PathwayBrowser/#/R-DRE-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Danio rerio 17984 R-DRE-1482635 https://reactome.org/PathwayBrowser/#/R-DRE-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Danio rerio 17984 R-DRE-1482689 https://reactome.org/PathwayBrowser/#/R-DRE-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Danio rerio 17984 R-DRE-1482695 https://reactome.org/PathwayBrowser/#/R-DRE-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Danio rerio 17984 R-DRE-1482775 https://reactome.org/PathwayBrowser/#/R-DRE-1482775 MLCL is acylated to CL by HADH (IM) IEA Danio rerio 17984 R-DRE-1482861 https://reactome.org/PathwayBrowser/#/R-DRE-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Danio rerio 17984 R-DRE-1482867 https://reactome.org/PathwayBrowser/#/R-DRE-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Danio rerio 17984 R-DRE-1482889 https://reactome.org/PathwayBrowser/#/R-DRE-1482889 DAG is acylated to TAG by DGAT1/2 IEA Danio rerio 17984 R-DRE-428127 https://reactome.org/PathwayBrowser/#/R-DRE-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Danio rerio 17984 R-DRE-428185 https://reactome.org/PathwayBrowser/#/R-DRE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Danio rerio 17984 R-DRE-549112 https://reactome.org/PathwayBrowser/#/R-DRE-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Danio rerio 17984 R-DRE-5696424 https://reactome.org/PathwayBrowser/#/R-DRE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Danio rerio 17984 R-DRE-5696448 https://reactome.org/PathwayBrowser/#/R-DRE-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Danio rerio 17984 R-DRE-6800334 https://reactome.org/PathwayBrowser/#/R-DRE-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Danio rerio 17984 R-DRE-75885 https://reactome.org/PathwayBrowser/#/R-DRE-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Danio rerio 17984 R-DRE-8848580 https://reactome.org/PathwayBrowser/#/R-DRE-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Danio rerio 17984 R-DRE-8874745 https://reactome.org/PathwayBrowser/#/R-DRE-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Danio rerio 17984 R-DRE-8876696 https://reactome.org/PathwayBrowser/#/R-DRE-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Danio rerio 17984 R-GGA-1482533 https://reactome.org/PathwayBrowser/#/R-GGA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus 17984 R-GGA-1482539 https://reactome.org/PathwayBrowser/#/R-GGA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Gallus gallus 17984 R-GGA-1482546 https://reactome.org/PathwayBrowser/#/R-GGA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Gallus gallus 17984 R-GGA-1482547 https://reactome.org/PathwayBrowser/#/R-GGA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus 17984 R-GGA-1482548 https://reactome.org/PathwayBrowser/#/R-GGA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Gallus gallus 17984 R-GGA-1482635 https://reactome.org/PathwayBrowser/#/R-GGA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Gallus gallus 17984 R-GGA-1482636 https://reactome.org/PathwayBrowser/#/R-GGA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus 17984 R-GGA-1482646 https://reactome.org/PathwayBrowser/#/R-GGA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Gallus gallus 17984 R-GGA-1482667 https://reactome.org/PathwayBrowser/#/R-GGA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Gallus gallus 17984 R-GGA-1482689 https://reactome.org/PathwayBrowser/#/R-GGA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Gallus gallus 17984 R-GGA-1482691 https://reactome.org/PathwayBrowser/#/R-GGA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus 17984 R-GGA-1482695 https://reactome.org/PathwayBrowser/#/R-GGA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Gallus gallus 17984 R-GGA-1482775 https://reactome.org/PathwayBrowser/#/R-GGA-1482775 MLCL is acylated to CL by HADH (IM) IEA Gallus gallus 17984 R-GGA-1482861 https://reactome.org/PathwayBrowser/#/R-GGA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Gallus gallus 17984 R-GGA-1482867 https://reactome.org/PathwayBrowser/#/R-GGA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Gallus gallus 17984 R-GGA-1482889 https://reactome.org/PathwayBrowser/#/R-GGA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Gallus gallus 17984 R-GGA-428127 https://reactome.org/PathwayBrowser/#/R-GGA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Gallus gallus 17984 R-GGA-428185 https://reactome.org/PathwayBrowser/#/R-GGA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Gallus gallus 17984 R-GGA-549112 https://reactome.org/PathwayBrowser/#/R-GGA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Gallus gallus 17984 R-GGA-5696424 https://reactome.org/PathwayBrowser/#/R-GGA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Gallus gallus 17984 R-GGA-5696448 https://reactome.org/PathwayBrowser/#/R-GGA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Gallus gallus 17984 R-GGA-6800334 https://reactome.org/PathwayBrowser/#/R-GGA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Gallus gallus 17984 R-GGA-75885 https://reactome.org/PathwayBrowser/#/R-GGA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Gallus gallus 17984 R-GGA-8848580 https://reactome.org/PathwayBrowser/#/R-GGA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Gallus gallus 17984 R-GGA-8874745 https://reactome.org/PathwayBrowser/#/R-GGA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Gallus gallus 17984 R-GGA-8876696 https://reactome.org/PathwayBrowser/#/R-GGA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Gallus gallus 17984 R-HSA-1482533 https://reactome.org/PathwayBrowser/#/R-HSA-1482533 2-acyl LPC is acylated to PC by LPCAT TAS Homo sapiens 17984 R-HSA-1482539 https://reactome.org/PathwayBrowser/#/R-HSA-1482539 1-acyl LPG is acylated to PG by LPGAT TAS Homo sapiens 17984 R-HSA-1482546 https://reactome.org/PathwayBrowser/#/R-HSA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) TAS Homo sapiens 17984 R-HSA-1482547 https://reactome.org/PathwayBrowser/#/R-HSA-1482547 1-acyl LPC is acylated to PC by LPCAT TAS Homo sapiens 17984 R-HSA-1482548 https://reactome.org/PathwayBrowser/#/R-HSA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) TAS Homo sapiens 17984 R-HSA-1482598 https://reactome.org/PathwayBrowser/#/R-HSA-1482598 1-acyl LPI is acylated to PI by MBOAT7 TAS Homo sapiens 17984 R-HSA-1482626 https://reactome.org/PathwayBrowser/#/R-HSA-1482626 2-acyl LPI is acylated to PI by MBOAT7 TAS Homo sapiens 17984 R-HSA-1482635 https://reactome.org/PathwayBrowser/#/R-HSA-1482635 2-acyl LPG is acylated to PG by LPGAT TAS Homo sapiens 17984 R-HSA-1482636 https://reactome.org/PathwayBrowser/#/R-HSA-1482636 1-acyl LPS is acylated to PS by LPSAT TAS Homo sapiens 17984 R-HSA-1482646 https://reactome.org/PathwayBrowser/#/R-HSA-1482646 2-acyl LPE is acylated to PE by LPEAT TAS Homo sapiens 17984 R-HSA-1482667 https://reactome.org/PathwayBrowser/#/R-HSA-1482667 1-acyl LPE is acylated to PE by LPEAT TAS Homo sapiens 17984 R-HSA-1482689 https://reactome.org/PathwayBrowser/#/R-HSA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) TAS Homo sapiens 17984 R-HSA-1482691 https://reactome.org/PathwayBrowser/#/R-HSA-1482691 2-acyl LPS is acylated to PS by LPSAT TAS Homo sapiens 17984 R-HSA-1482695 https://reactome.org/PathwayBrowser/#/R-HSA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) TAS Homo sapiens 17984 R-HSA-1482775 https://reactome.org/PathwayBrowser/#/R-HSA-1482775 MLCL is acylated to CL by HADH (IM) TAS Homo sapiens 17984 R-HSA-1482861 https://reactome.org/PathwayBrowser/#/R-HSA-1482861 MLCL is acylated to CL by LCLAT1 (ER) TAS Homo sapiens 17984 R-HSA-1482867 https://reactome.org/PathwayBrowser/#/R-HSA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) TAS Homo sapiens 17984 R-HSA-1482889 https://reactome.org/PathwayBrowser/#/R-HSA-1482889 DAG is acylated to TAG by DGAT1/2 TAS Homo sapiens 17984 R-HSA-1483002 https://reactome.org/PathwayBrowser/#/R-HSA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT TAS Homo sapiens 17984 R-HSA-428127 https://reactome.org/PathwayBrowser/#/R-HSA-428127 SPTLC complexes transfer acyl-CoA onto serine TAS Homo sapiens 17984 R-HSA-428185 https://reactome.org/PathwayBrowser/#/R-HSA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid TAS Homo sapiens 17984 R-HSA-549112 https://reactome.org/PathwayBrowser/#/R-HSA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 TAS Homo sapiens 17984 R-HSA-5696424 https://reactome.org/PathwayBrowser/#/R-HSA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters TAS Homo sapiens 17984 R-HSA-5696448 https://reactome.org/PathwayBrowser/#/R-HSA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG TAS Homo sapiens 17984 R-HSA-6800334 https://reactome.org/PathwayBrowser/#/R-HSA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG TAS Homo sapiens 17984 R-HSA-75885 https://reactome.org/PathwayBrowser/#/R-HSA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) TAS Homo sapiens 17984 R-HSA-8848580 https://reactome.org/PathwayBrowser/#/R-HSA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG TAS Homo sapiens 17984 R-HSA-8874745 https://reactome.org/PathwayBrowser/#/R-HSA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH TAS Homo sapiens 17984 R-HSA-8876696 https://reactome.org/PathwayBrowser/#/R-HSA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST TAS Homo sapiens 17984 R-MMU-1482533 https://reactome.org/PathwayBrowser/#/R-MMU-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Mus musculus 17984 R-MMU-1482539 https://reactome.org/PathwayBrowser/#/R-MMU-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Mus musculus 17984 R-MMU-1482546 https://reactome.org/PathwayBrowser/#/R-MMU-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Mus musculus 17984 R-MMU-1482547 https://reactome.org/PathwayBrowser/#/R-MMU-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Mus musculus 17984 R-MMU-1482548 https://reactome.org/PathwayBrowser/#/R-MMU-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Mus musculus 17984 R-MMU-1482598 https://reactome.org/PathwayBrowser/#/R-MMU-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Mus musculus 17984 R-MMU-1482626 https://reactome.org/PathwayBrowser/#/R-MMU-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Mus musculus 17984 R-MMU-1482635 https://reactome.org/PathwayBrowser/#/R-MMU-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Mus musculus 17984 R-MMU-1482636 https://reactome.org/PathwayBrowser/#/R-MMU-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Mus musculus 17984 R-MMU-1482646 https://reactome.org/PathwayBrowser/#/R-MMU-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Mus musculus 17984 R-MMU-1482667 https://reactome.org/PathwayBrowser/#/R-MMU-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Mus musculus 17984 R-MMU-1482689 https://reactome.org/PathwayBrowser/#/R-MMU-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Mus musculus 17984 R-MMU-1482691 https://reactome.org/PathwayBrowser/#/R-MMU-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Mus musculus 17984 R-MMU-1482695 https://reactome.org/PathwayBrowser/#/R-MMU-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Mus musculus 17984 R-MMU-1482775 https://reactome.org/PathwayBrowser/#/R-MMU-1482775 MLCL is acylated to CL by HADH (IM) IEA Mus musculus 17984 R-MMU-1482861 https://reactome.org/PathwayBrowser/#/R-MMU-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Mus musculus 17984 R-MMU-1482867 https://reactome.org/PathwayBrowser/#/R-MMU-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Mus musculus 17984 R-MMU-1482889 https://reactome.org/PathwayBrowser/#/R-MMU-1482889 DAG is acylated to TAG by DGAT1/2 IEA Mus musculus 17984 R-MMU-1483002 https://reactome.org/PathwayBrowser/#/R-MMU-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Mus musculus 17984 R-MMU-428127 https://reactome.org/PathwayBrowser/#/R-MMU-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Mus musculus 17984 R-MMU-428185 https://reactome.org/PathwayBrowser/#/R-MMU-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Mus musculus 17984 R-MMU-549112 https://reactome.org/PathwayBrowser/#/R-MMU-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Mus musculus 17984 R-MMU-5696424 https://reactome.org/PathwayBrowser/#/R-MMU-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Mus musculus 17984 R-MMU-5696448 https://reactome.org/PathwayBrowser/#/R-MMU-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Mus musculus 17984 R-MMU-6800334 https://reactome.org/PathwayBrowser/#/R-MMU-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Mus musculus 17984 R-MMU-75885 https://reactome.org/PathwayBrowser/#/R-MMU-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Mus musculus 17984 R-MMU-8848580 https://reactome.org/PathwayBrowser/#/R-MMU-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Mus musculus 17984 R-MMU-8874745 https://reactome.org/PathwayBrowser/#/R-MMU-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Mus musculus 17984 R-MMU-8876696 https://reactome.org/PathwayBrowser/#/R-MMU-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Mus musculus 17984 R-PFA-1482533 https://reactome.org/PathwayBrowser/#/R-PFA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Plasmodium falciparum 17984 R-PFA-1482539 https://reactome.org/PathwayBrowser/#/R-PFA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Plasmodium falciparum 17984 R-PFA-1482547 https://reactome.org/PathwayBrowser/#/R-PFA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Plasmodium falciparum 17984 R-PFA-1482635 https://reactome.org/PathwayBrowser/#/R-PFA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Plasmodium falciparum 17984 R-PFA-1482636 https://reactome.org/PathwayBrowser/#/R-PFA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Plasmodium falciparum 17984 R-PFA-1482646 https://reactome.org/PathwayBrowser/#/R-PFA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Plasmodium falciparum 17984 R-PFA-1482667 https://reactome.org/PathwayBrowser/#/R-PFA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Plasmodium falciparum 17984 R-PFA-1482691 https://reactome.org/PathwayBrowser/#/R-PFA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Plasmodium falciparum 17984 R-PFA-1482889 https://reactome.org/PathwayBrowser/#/R-PFA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Plasmodium falciparum 17984 R-PFA-428185 https://reactome.org/PathwayBrowser/#/R-PFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Plasmodium falciparum 17984 R-PFA-75885 https://reactome.org/PathwayBrowser/#/R-PFA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Plasmodium falciparum 17984 R-RNO-1482533 https://reactome.org/PathwayBrowser/#/R-RNO-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Rattus norvegicus 17984 R-RNO-1482539 https://reactome.org/PathwayBrowser/#/R-RNO-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Rattus norvegicus 17984 R-RNO-1482546 https://reactome.org/PathwayBrowser/#/R-RNO-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Rattus norvegicus 17984 R-RNO-1482547 https://reactome.org/PathwayBrowser/#/R-RNO-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Rattus norvegicus 17984 R-RNO-1482548 https://reactome.org/PathwayBrowser/#/R-RNO-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Rattus norvegicus 17984 R-RNO-1482635 https://reactome.org/PathwayBrowser/#/R-RNO-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Rattus norvegicus 17984 R-RNO-1482636 https://reactome.org/PathwayBrowser/#/R-RNO-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Rattus norvegicus 17984 R-RNO-1482646 https://reactome.org/PathwayBrowser/#/R-RNO-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Rattus norvegicus 17984 R-RNO-1482667 https://reactome.org/PathwayBrowser/#/R-RNO-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Rattus norvegicus 17984 R-RNO-1482689 https://reactome.org/PathwayBrowser/#/R-RNO-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Rattus norvegicus 17984 R-RNO-1482691 https://reactome.org/PathwayBrowser/#/R-RNO-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Rattus norvegicus 17984 R-RNO-1482695 https://reactome.org/PathwayBrowser/#/R-RNO-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Rattus norvegicus 17984 R-RNO-1482775 https://reactome.org/PathwayBrowser/#/R-RNO-1482775 MLCL is acylated to CL by HADH (IM) IEA Rattus norvegicus 17984 R-RNO-1482861 https://reactome.org/PathwayBrowser/#/R-RNO-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Rattus norvegicus 17984 R-RNO-1482867 https://reactome.org/PathwayBrowser/#/R-RNO-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Rattus norvegicus 17984 R-RNO-1482889 https://reactome.org/PathwayBrowser/#/R-RNO-1482889 DAG is acylated to TAG by DGAT1/2 IEA Rattus norvegicus 17984 R-RNO-1483002 https://reactome.org/PathwayBrowser/#/R-RNO-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Rattus norvegicus 17984 R-RNO-428127 https://reactome.org/PathwayBrowser/#/R-RNO-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Rattus norvegicus 17984 R-RNO-428185 https://reactome.org/PathwayBrowser/#/R-RNO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Rattus norvegicus 17984 R-RNO-549112 https://reactome.org/PathwayBrowser/#/R-RNO-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Rattus norvegicus 17984 R-RNO-5696424 https://reactome.org/PathwayBrowser/#/R-RNO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Rattus norvegicus 17984 R-RNO-5696448 https://reactome.org/PathwayBrowser/#/R-RNO-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Rattus norvegicus 17984 R-RNO-6800334 https://reactome.org/PathwayBrowser/#/R-RNO-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Rattus norvegicus 17984 R-RNO-75885 https://reactome.org/PathwayBrowser/#/R-RNO-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Rattus norvegicus 17984 R-RNO-8848580 https://reactome.org/PathwayBrowser/#/R-RNO-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Rattus norvegicus 17984 R-RNO-8874745 https://reactome.org/PathwayBrowser/#/R-RNO-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Rattus norvegicus 17984 R-RNO-8876696 https://reactome.org/PathwayBrowser/#/R-RNO-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Rattus norvegicus 17984 R-SCE-1482533 https://reactome.org/PathwayBrowser/#/R-SCE-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Saccharomyces cerevisiae 17984 R-SCE-1482539 https://reactome.org/PathwayBrowser/#/R-SCE-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Saccharomyces cerevisiae 17984 R-SCE-1482546 https://reactome.org/PathwayBrowser/#/R-SCE-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Saccharomyces cerevisiae 17984 R-SCE-1482547 https://reactome.org/PathwayBrowser/#/R-SCE-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Saccharomyces cerevisiae 17984 R-SCE-1482598 https://reactome.org/PathwayBrowser/#/R-SCE-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Saccharomyces cerevisiae 17984 R-SCE-1482626 https://reactome.org/PathwayBrowser/#/R-SCE-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Saccharomyces cerevisiae 17984 R-SCE-1482635 https://reactome.org/PathwayBrowser/#/R-SCE-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Saccharomyces cerevisiae 17984 R-SCE-1482636 https://reactome.org/PathwayBrowser/#/R-SCE-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Saccharomyces cerevisiae 17984 R-SCE-1482646 https://reactome.org/PathwayBrowser/#/R-SCE-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Saccharomyces cerevisiae 17984 R-SCE-1482667 https://reactome.org/PathwayBrowser/#/R-SCE-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Saccharomyces cerevisiae 17984 R-SCE-1482689 https://reactome.org/PathwayBrowser/#/R-SCE-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Saccharomyces cerevisiae 17984 R-SCE-1482691 https://reactome.org/PathwayBrowser/#/R-SCE-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Saccharomyces cerevisiae 17984 R-SCE-1482861 https://reactome.org/PathwayBrowser/#/R-SCE-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Saccharomyces cerevisiae 17984 R-SCE-1482867 https://reactome.org/PathwayBrowser/#/R-SCE-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Saccharomyces cerevisiae 17984 R-SCE-1482889 https://reactome.org/PathwayBrowser/#/R-SCE-1482889 DAG is acylated to TAG by DGAT1/2 IEA Saccharomyces cerevisiae 17984 R-SCE-428185 https://reactome.org/PathwayBrowser/#/R-SCE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Saccharomyces cerevisiae 17984 R-SCE-5696424 https://reactome.org/PathwayBrowser/#/R-SCE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Saccharomyces cerevisiae 17984 R-SCE-5696448 https://reactome.org/PathwayBrowser/#/R-SCE-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Saccharomyces cerevisiae 17984 R-SCE-6800334 https://reactome.org/PathwayBrowser/#/R-SCE-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Saccharomyces cerevisiae 17984 R-SCE-75885 https://reactome.org/PathwayBrowser/#/R-SCE-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Saccharomyces cerevisiae 17984 R-SCE-8848580 https://reactome.org/PathwayBrowser/#/R-SCE-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Saccharomyces cerevisiae 17984 R-SPO-1482533 https://reactome.org/PathwayBrowser/#/R-SPO-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Schizosaccharomyces pombe 17984 R-SPO-1482539 https://reactome.org/PathwayBrowser/#/R-SPO-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Schizosaccharomyces pombe 17984 R-SPO-1482546 https://reactome.org/PathwayBrowser/#/R-SPO-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Schizosaccharomyces pombe 17984 R-SPO-1482547 https://reactome.org/PathwayBrowser/#/R-SPO-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Schizosaccharomyces pombe 17984 R-SPO-1482598 https://reactome.org/PathwayBrowser/#/R-SPO-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Schizosaccharomyces pombe 17984 R-SPO-1482626 https://reactome.org/PathwayBrowser/#/R-SPO-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Schizosaccharomyces pombe 17984 R-SPO-1482635 https://reactome.org/PathwayBrowser/#/R-SPO-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Schizosaccharomyces pombe 17984 R-SPO-1482636 https://reactome.org/PathwayBrowser/#/R-SPO-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Schizosaccharomyces pombe 17984 R-SPO-1482646 https://reactome.org/PathwayBrowser/#/R-SPO-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Schizosaccharomyces pombe 17984 R-SPO-1482667 https://reactome.org/PathwayBrowser/#/R-SPO-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Schizosaccharomyces pombe 17984 R-SPO-1482689 https://reactome.org/PathwayBrowser/#/R-SPO-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Schizosaccharomyces pombe 17984 R-SPO-1482691 https://reactome.org/PathwayBrowser/#/R-SPO-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Schizosaccharomyces pombe 17984 R-SPO-1482861 https://reactome.org/PathwayBrowser/#/R-SPO-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Schizosaccharomyces pombe 17984 R-SPO-1482867 https://reactome.org/PathwayBrowser/#/R-SPO-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Schizosaccharomyces pombe 17984 R-SPO-1482889 https://reactome.org/PathwayBrowser/#/R-SPO-1482889 DAG is acylated to TAG by DGAT1/2 IEA Schizosaccharomyces pombe 17984 R-SPO-428185 https://reactome.org/PathwayBrowser/#/R-SPO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Schizosaccharomyces pombe 17984 R-SPO-5696424 https://reactome.org/PathwayBrowser/#/R-SPO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Schizosaccharomyces pombe 17984 R-SPO-5696448 https://reactome.org/PathwayBrowser/#/R-SPO-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Schizosaccharomyces pombe 17984 R-SPO-6800334 https://reactome.org/PathwayBrowser/#/R-SPO-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Schizosaccharomyces pombe 17984 R-SPO-75885 https://reactome.org/PathwayBrowser/#/R-SPO-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Schizosaccharomyces pombe 17984 R-SPO-8848580 https://reactome.org/PathwayBrowser/#/R-SPO-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Schizosaccharomyces pombe 17984 R-SSC-1482533 https://reactome.org/PathwayBrowser/#/R-SSC-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Sus scrofa 17984 R-SSC-1482539 https://reactome.org/PathwayBrowser/#/R-SSC-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa 17984 R-SSC-1482546 https://reactome.org/PathwayBrowser/#/R-SSC-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Sus scrofa 17984 R-SSC-1482547 https://reactome.org/PathwayBrowser/#/R-SSC-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Sus scrofa 17984 R-SSC-1482548 https://reactome.org/PathwayBrowser/#/R-SSC-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Sus scrofa 17984 R-SSC-1482598 https://reactome.org/PathwayBrowser/#/R-SSC-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Sus scrofa 17984 R-SSC-1482626 https://reactome.org/PathwayBrowser/#/R-SSC-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Sus scrofa 17984 R-SSC-1482635 https://reactome.org/PathwayBrowser/#/R-SSC-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa 17984 R-SSC-1482636 https://reactome.org/PathwayBrowser/#/R-SSC-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa 17984 R-SSC-1482646 https://reactome.org/PathwayBrowser/#/R-SSC-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Sus scrofa 17984 R-SSC-1482667 https://reactome.org/PathwayBrowser/#/R-SSC-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Sus scrofa 17984 R-SSC-1482689 https://reactome.org/PathwayBrowser/#/R-SSC-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Sus scrofa 17984 R-SSC-1482691 https://reactome.org/PathwayBrowser/#/R-SSC-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa 17984 R-SSC-1482695 https://reactome.org/PathwayBrowser/#/R-SSC-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Sus scrofa 17984 R-SSC-1482775 https://reactome.org/PathwayBrowser/#/R-SSC-1482775 MLCL is acylated to CL by HADH (IM) IEA Sus scrofa 17984 R-SSC-1482861 https://reactome.org/PathwayBrowser/#/R-SSC-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Sus scrofa 17984 R-SSC-1482867 https://reactome.org/PathwayBrowser/#/R-SSC-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Sus scrofa 17984 R-SSC-1482889 https://reactome.org/PathwayBrowser/#/R-SSC-1482889 DAG is acylated to TAG by DGAT1/2 IEA Sus scrofa 17984 R-SSC-1483002 https://reactome.org/PathwayBrowser/#/R-SSC-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Sus scrofa 17984 R-SSC-428127 https://reactome.org/PathwayBrowser/#/R-SSC-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Sus scrofa 17984 R-SSC-428185 https://reactome.org/PathwayBrowser/#/R-SSC-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Sus scrofa 17984 R-SSC-549112 https://reactome.org/PathwayBrowser/#/R-SSC-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Sus scrofa 17984 R-SSC-5696448 https://reactome.org/PathwayBrowser/#/R-SSC-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Sus scrofa 17984 R-SSC-6800334 https://reactome.org/PathwayBrowser/#/R-SSC-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Sus scrofa 17984 R-SSC-75885 https://reactome.org/PathwayBrowser/#/R-SSC-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Sus scrofa 17984 R-SSC-8848580 https://reactome.org/PathwayBrowser/#/R-SSC-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Sus scrofa 17984 R-SSC-8874745 https://reactome.org/PathwayBrowser/#/R-SSC-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Sus scrofa 17984 R-SSC-8876696 https://reactome.org/PathwayBrowser/#/R-SSC-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Sus scrofa 17984 R-XTR-1482533 https://reactome.org/PathwayBrowser/#/R-XTR-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Xenopus tropicalis 17984 R-XTR-1482539 https://reactome.org/PathwayBrowser/#/R-XTR-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Xenopus tropicalis 17984 R-XTR-1482547 https://reactome.org/PathwayBrowser/#/R-XTR-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Xenopus tropicalis 17984 R-XTR-1482598 https://reactome.org/PathwayBrowser/#/R-XTR-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Xenopus tropicalis 17984 R-XTR-1482626 https://reactome.org/PathwayBrowser/#/R-XTR-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Xenopus tropicalis 17984 R-XTR-1482635 https://reactome.org/PathwayBrowser/#/R-XTR-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Xenopus tropicalis 17984 R-XTR-1482636 https://reactome.org/PathwayBrowser/#/R-XTR-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Xenopus tropicalis 17984 R-XTR-1482646 https://reactome.org/PathwayBrowser/#/R-XTR-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Xenopus tropicalis 17984 R-XTR-1482667 https://reactome.org/PathwayBrowser/#/R-XTR-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Xenopus tropicalis 17984 R-XTR-1482691 https://reactome.org/PathwayBrowser/#/R-XTR-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Xenopus tropicalis 17984 R-XTR-1482695 https://reactome.org/PathwayBrowser/#/R-XTR-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Xenopus tropicalis 17984 R-XTR-1482775 https://reactome.org/PathwayBrowser/#/R-XTR-1482775 MLCL is acylated to CL by HADH (IM) IEA Xenopus tropicalis 17984 R-XTR-1482861 https://reactome.org/PathwayBrowser/#/R-XTR-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Xenopus tropicalis 17984 R-XTR-1482867 https://reactome.org/PathwayBrowser/#/R-XTR-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Xenopus tropicalis 17984 R-XTR-1482889 https://reactome.org/PathwayBrowser/#/R-XTR-1482889 DAG is acylated to TAG by DGAT1/2 IEA Xenopus tropicalis 17984 R-XTR-1483002 https://reactome.org/PathwayBrowser/#/R-XTR-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Xenopus tropicalis 17984 R-XTR-428127 https://reactome.org/PathwayBrowser/#/R-XTR-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Xenopus tropicalis 17984 R-XTR-428185 https://reactome.org/PathwayBrowser/#/R-XTR-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Xenopus tropicalis 17984 R-XTR-549112 https://reactome.org/PathwayBrowser/#/R-XTR-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Xenopus tropicalis 17984 R-XTR-5696424 https://reactome.org/PathwayBrowser/#/R-XTR-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Xenopus tropicalis 17984 R-XTR-5696448 https://reactome.org/PathwayBrowser/#/R-XTR-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Xenopus tropicalis 17984 R-XTR-6800334 https://reactome.org/PathwayBrowser/#/R-XTR-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Xenopus tropicalis 17984 R-XTR-75885 https://reactome.org/PathwayBrowser/#/R-XTR-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Xenopus tropicalis 17984 R-XTR-8848580 https://reactome.org/PathwayBrowser/#/R-XTR-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Xenopus tropicalis 17984 R-XTR-8874745 https://reactome.org/PathwayBrowser/#/R-XTR-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Xenopus tropicalis 17984 R-XTR-8876696 https://reactome.org/PathwayBrowser/#/R-XTR-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Xenopus tropicalis 179906 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 179906 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 179906 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 179906 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 179906 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 179906 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 179906 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 179906 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 179906 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 17992 R-BTA-189069 https://reactome.org/PathwayBrowser/#/R-BTA-189069 sucrose + H2O => glucose + fructose IEA Bos taurus 17992 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 17992 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 17992 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 17992 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 17992 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 17992 R-CEL-189069 https://reactome.org/PathwayBrowser/#/R-CEL-189069 sucrose + H2O => glucose + fructose IEA Caenorhabditis elegans 17992 R-CFA-189069 https://reactome.org/PathwayBrowser/#/R-CFA-189069 sucrose + H2O => glucose + fructose IEA Canis familiaris 17992 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 17992 R-DDI-189069 https://reactome.org/PathwayBrowser/#/R-DDI-189069 sucrose + H2O => glucose + fructose IEA Dictyostelium discoideum 17992 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 17992 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 17992 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 17992 R-GGA-189069 https://reactome.org/PathwayBrowser/#/R-GGA-189069 sucrose + H2O => glucose + fructose IEA Gallus gallus 17992 R-HSA-189069 https://reactome.org/PathwayBrowser/#/R-HSA-189069 sucrose + H2O => glucose + fructose TAS Homo sapiens 17992 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 17992 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 17992 R-HSA-5659926 https://reactome.org/PathwayBrowser/#/R-HSA-5659926 Defective SI does not hydrolyze Suc IEA Homo sapiens 17992 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 17992 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 17992 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 17992 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 17992 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 17992 R-MMU-189069 https://reactome.org/PathwayBrowser/#/R-MMU-189069 sucrose + H2O => glucose + fructose IEA Mus musculus 17992 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 17992 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 17992 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 17992 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 17992 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 17992 R-RNO-189069 https://reactome.org/PathwayBrowser/#/R-RNO-189069 sucrose + H2O => glucose + fructose IEA Rattus norvegicus 17992 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 17992 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 17992 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 17992 R-SPO-189069 https://reactome.org/PathwayBrowser/#/R-SPO-189069 sucrose + H2O => glucose + fructose IEA Schizosaccharomyces pombe 17992 R-SSC-189069 https://reactome.org/PathwayBrowser/#/R-SSC-189069 sucrose + H2O => glucose + fructose IEA Sus scrofa 17992 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 17992 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 17992 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 17992 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 17992 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 17996 R-BTA-1237038 https://reactome.org/PathwayBrowser/#/R-BTA-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Bos taurus 17996 R-BTA-1247665 https://reactome.org/PathwayBrowser/#/R-BTA-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Bos taurus 17996 R-BTA-2022405 https://reactome.org/PathwayBrowser/#/R-BTA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 17996 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 17996 R-BTA-2684901 https://reactome.org/PathwayBrowser/#/R-BTA-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Bos taurus 17996 R-BTA-2730692 https://reactome.org/PathwayBrowser/#/R-BTA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Bos taurus 17996 R-BTA-2730959 https://reactome.org/PathwayBrowser/#/R-BTA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Bos taurus 17996 R-BTA-2744228 https://reactome.org/PathwayBrowser/#/R-BTA-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region IEA Bos taurus 17996 R-BTA-2744242 https://reactome.org/PathwayBrowser/#/R-BTA-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Bos taurus 17996 R-BTA-2744349 https://reactome.org/PathwayBrowser/#/R-BTA-2744349 TTYH1 transports cytosolic Cl- to extracellular region IEA Bos taurus 17996 R-BTA-2744361 https://reactome.org/PathwayBrowser/#/R-BTA-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Bos taurus 17996 R-BTA-351987 https://reactome.org/PathwayBrowser/#/R-BTA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Bos taurus 17996 R-BTA-352029 https://reactome.org/PathwayBrowser/#/R-BTA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Bos taurus 17996 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 17996 R-BTA-425482 https://reactome.org/PathwayBrowser/#/R-BTA-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Bos taurus 17996 R-BTA-425577 https://reactome.org/PathwayBrowser/#/R-BTA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Bos taurus 17996 R-BTA-426086 https://reactome.org/PathwayBrowser/#/R-BTA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Bos taurus 17996 R-BTA-426130 https://reactome.org/PathwayBrowser/#/R-BTA-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 17996 R-BTA-426155 https://reactome.org/PathwayBrowser/#/R-BTA-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Bos taurus 17996 R-BTA-427570 https://reactome.org/PathwayBrowser/#/R-BTA-427570 Group 3 - Selective Cl- transport IEA Bos taurus 17996 R-BTA-427666 https://reactome.org/PathwayBrowser/#/R-BTA-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Bos taurus 17996 R-BTA-429594 https://reactome.org/PathwayBrowser/#/R-BTA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 17996 R-BTA-444007 https://reactome.org/PathwayBrowser/#/R-BTA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Bos taurus 17996 R-BTA-444008 https://reactome.org/PathwayBrowser/#/R-BTA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 17996 R-BTA-444100 https://reactome.org/PathwayBrowser/#/R-BTA-444100 PROT mediates L-proline uptake IEA Bos taurus 17996 R-BTA-444120 https://reactome.org/PathwayBrowser/#/R-BTA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 17996 R-BTA-451283 https://reactome.org/PathwayBrowser/#/R-BTA-451283 kainate receptor binds glutamate IEA Bos taurus 17996 R-BTA-451309 https://reactome.org/PathwayBrowser/#/R-BTA-451309 Edited Kainate Receptor binds glutamate IEA Bos taurus 17996 R-BTA-451310 https://reactome.org/PathwayBrowser/#/R-BTA-451310 Activation of Edited Kainate receptors IEA Bos taurus 17996 R-BTA-451311 https://reactome.org/PathwayBrowser/#/R-BTA-451311 Activation of Ca-permeable Kainate receptors IEA Bos taurus 17996 R-BTA-500708 https://reactome.org/PathwayBrowser/#/R-BTA-500708 GRIK3 homomer binds glutamate IEA Bos taurus 17996 R-BTA-500717 https://reactome.org/PathwayBrowser/#/R-BTA-500717 Activation of GRIK3 homomer IEA Bos taurus 17996 R-BTA-5678863 https://reactome.org/PathwayBrowser/#/R-BTA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Bos taurus 17996 R-BTA-6789031 https://reactome.org/PathwayBrowser/#/R-BTA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 17996 R-BTA-6789126 https://reactome.org/PathwayBrowser/#/R-BTA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 17996 R-BTA-76434 https://reactome.org/PathwayBrowser/#/R-BTA-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Bos taurus 17996 R-BTA-8941543 https://reactome.org/PathwayBrowser/#/R-BTA-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Bos taurus 17996 R-BTA-9011595 https://reactome.org/PathwayBrowser/#/R-BTA-9011595 GSTZ1 dimer dehalogenates DCA IEA Bos taurus 17996 R-BTA-9659568 https://reactome.org/PathwayBrowser/#/R-BTA-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Bos taurus 17996 R-BTA-975340 https://reactome.org/PathwayBrowser/#/R-BTA-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Bos taurus 17996 R-BTA-975389 https://reactome.org/PathwayBrowser/#/R-BTA-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Bos taurus 17996 R-BTA-975449 https://reactome.org/PathwayBrowser/#/R-BTA-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Bos taurus 17996 R-CEL-1237038 https://reactome.org/PathwayBrowser/#/R-CEL-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Caenorhabditis elegans 17996 R-CEL-1247665 https://reactome.org/PathwayBrowser/#/R-CEL-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Caenorhabditis elegans 17996 R-CEL-2022405 https://reactome.org/PathwayBrowser/#/R-CEL-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 17996 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 17996 R-CEL-2684901 https://reactome.org/PathwayBrowser/#/R-CEL-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Caenorhabditis elegans 17996 R-CEL-2730692 https://reactome.org/PathwayBrowser/#/R-CEL-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Caenorhabditis elegans 17996 R-CEL-2730959 https://reactome.org/PathwayBrowser/#/R-CEL-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Caenorhabditis elegans 17996 R-CEL-2744228 https://reactome.org/PathwayBrowser/#/R-CEL-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region IEA Caenorhabditis elegans 17996 R-CEL-2744242 https://reactome.org/PathwayBrowser/#/R-CEL-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Caenorhabditis elegans 17996 R-CEL-2744349 https://reactome.org/PathwayBrowser/#/R-CEL-2744349 TTYH1 transports cytosolic Cl- to extracellular region IEA Caenorhabditis elegans 17996 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 17996 R-CEL-425482 https://reactome.org/PathwayBrowser/#/R-CEL-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Caenorhabditis elegans 17996 R-CEL-425577 https://reactome.org/PathwayBrowser/#/R-CEL-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Caenorhabditis elegans 17996 R-CEL-426086 https://reactome.org/PathwayBrowser/#/R-CEL-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Caenorhabditis elegans 17996 R-CEL-426130 https://reactome.org/PathwayBrowser/#/R-CEL-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 17996 R-CEL-426155 https://reactome.org/PathwayBrowser/#/R-CEL-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Caenorhabditis elegans 17996 R-CEL-427570 https://reactome.org/PathwayBrowser/#/R-CEL-427570 Group 3 - Selective Cl- transport IEA Caenorhabditis elegans 17996 R-CEL-427666 https://reactome.org/PathwayBrowser/#/R-CEL-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Caenorhabditis elegans 17996 R-CEL-429594 https://reactome.org/PathwayBrowser/#/R-CEL-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 17996 R-CEL-444007 https://reactome.org/PathwayBrowser/#/R-CEL-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Caenorhabditis elegans 17996 R-CEL-444008 https://reactome.org/PathwayBrowser/#/R-CEL-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 17996 R-CEL-444100 https://reactome.org/PathwayBrowser/#/R-CEL-444100 PROT mediates L-proline uptake IEA Caenorhabditis elegans 17996 R-CEL-444120 https://reactome.org/PathwayBrowser/#/R-CEL-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 17996 R-CEL-451283 https://reactome.org/PathwayBrowser/#/R-CEL-451283 kainate receptor binds glutamate IEA Caenorhabditis elegans 17996 R-CEL-451311 https://reactome.org/PathwayBrowser/#/R-CEL-451311 Activation of Ca-permeable Kainate receptors IEA Caenorhabditis elegans 17996 R-CEL-5678863 https://reactome.org/PathwayBrowser/#/R-CEL-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Caenorhabditis elegans 17996 R-CEL-6789031 https://reactome.org/PathwayBrowser/#/R-CEL-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 17996 R-CEL-6789126 https://reactome.org/PathwayBrowser/#/R-CEL-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 17996 R-CEL-76434 https://reactome.org/PathwayBrowser/#/R-CEL-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Caenorhabditis elegans 17996 R-CEL-8941543 https://reactome.org/PathwayBrowser/#/R-CEL-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Caenorhabditis elegans 17996 R-CEL-9011595 https://reactome.org/PathwayBrowser/#/R-CEL-9011595 GSTZ1 dimer dehalogenates DCA IEA Caenorhabditis elegans 17996 R-CEL-975340 https://reactome.org/PathwayBrowser/#/R-CEL-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Caenorhabditis elegans 17996 R-CEL-975389 https://reactome.org/PathwayBrowser/#/R-CEL-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Caenorhabditis elegans 17996 R-CEL-975449 https://reactome.org/PathwayBrowser/#/R-CEL-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Caenorhabditis elegans 17996 R-CFA-1237038 https://reactome.org/PathwayBrowser/#/R-CFA-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Canis familiaris 17996 R-CFA-1247665 https://reactome.org/PathwayBrowser/#/R-CFA-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Canis familiaris 17996 R-CFA-2022405 https://reactome.org/PathwayBrowser/#/R-CFA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 17996 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 17996 R-CFA-2684901 https://reactome.org/PathwayBrowser/#/R-CFA-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Canis familiaris 17996 R-CFA-2730692 https://reactome.org/PathwayBrowser/#/R-CFA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Canis familiaris 17996 R-CFA-2730959 https://reactome.org/PathwayBrowser/#/R-CFA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Canis familiaris 17996 R-CFA-2744228 https://reactome.org/PathwayBrowser/#/R-CFA-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region IEA Canis familiaris 17996 R-CFA-2744242 https://reactome.org/PathwayBrowser/#/R-CFA-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Canis familiaris 17996 R-CFA-2744349 https://reactome.org/PathwayBrowser/#/R-CFA-2744349 TTYH1 transports cytosolic Cl- to extracellular region IEA Canis familiaris 17996 R-CFA-2744361 https://reactome.org/PathwayBrowser/#/R-CFA-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Canis familiaris 17996 R-CFA-351987 https://reactome.org/PathwayBrowser/#/R-CFA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Canis familiaris 17996 R-CFA-352029 https://reactome.org/PathwayBrowser/#/R-CFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Canis familiaris 17996 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 17996 R-CFA-425482 https://reactome.org/PathwayBrowser/#/R-CFA-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Canis familiaris 17996 R-CFA-425577 https://reactome.org/PathwayBrowser/#/R-CFA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Canis familiaris 17996 R-CFA-426086 https://reactome.org/PathwayBrowser/#/R-CFA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Canis familiaris 17996 R-CFA-426130 https://reactome.org/PathwayBrowser/#/R-CFA-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 17996 R-CFA-426155 https://reactome.org/PathwayBrowser/#/R-CFA-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Canis familiaris 17996 R-CFA-427570 https://reactome.org/PathwayBrowser/#/R-CFA-427570 Group 3 - Selective Cl- transport IEA Canis familiaris 17996 R-CFA-427666 https://reactome.org/PathwayBrowser/#/R-CFA-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Canis familiaris 17996 R-CFA-429594 https://reactome.org/PathwayBrowser/#/R-CFA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 17996 R-CFA-444007 https://reactome.org/PathwayBrowser/#/R-CFA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Canis familiaris 17996 R-CFA-444008 https://reactome.org/PathwayBrowser/#/R-CFA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 17996 R-CFA-444100 https://reactome.org/PathwayBrowser/#/R-CFA-444100 PROT mediates L-proline uptake IEA Canis familiaris 17996 R-CFA-444120 https://reactome.org/PathwayBrowser/#/R-CFA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 17996 R-CFA-451283 https://reactome.org/PathwayBrowser/#/R-CFA-451283 kainate receptor binds glutamate IEA Canis familiaris 17996 R-CFA-451309 https://reactome.org/PathwayBrowser/#/R-CFA-451309 Edited Kainate Receptor binds glutamate IEA Canis familiaris 17996 R-CFA-451310 https://reactome.org/PathwayBrowser/#/R-CFA-451310 Activation of Edited Kainate receptors IEA Canis familiaris 17996 R-CFA-451311 https://reactome.org/PathwayBrowser/#/R-CFA-451311 Activation of Ca-permeable Kainate receptors IEA Canis familiaris 17996 R-CFA-500708 https://reactome.org/PathwayBrowser/#/R-CFA-500708 GRIK3 homomer binds glutamate IEA Canis familiaris 17996 R-CFA-500717 https://reactome.org/PathwayBrowser/#/R-CFA-500717 Activation of GRIK3 homomer IEA Canis familiaris 17996 R-CFA-5678863 https://reactome.org/PathwayBrowser/#/R-CFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Canis familiaris 17996 R-CFA-6789031 https://reactome.org/PathwayBrowser/#/R-CFA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 17996 R-CFA-6789126 https://reactome.org/PathwayBrowser/#/R-CFA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 17996 R-CFA-76434 https://reactome.org/PathwayBrowser/#/R-CFA-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Canis familiaris 17996 R-CFA-8941543 https://reactome.org/PathwayBrowser/#/R-CFA-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Canis familiaris 17996 R-CFA-9011595 https://reactome.org/PathwayBrowser/#/R-CFA-9011595 GSTZ1 dimer dehalogenates DCA IEA Canis familiaris 17996 R-CFA-9659568 https://reactome.org/PathwayBrowser/#/R-CFA-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Canis familiaris 17996 R-CFA-975340 https://reactome.org/PathwayBrowser/#/R-CFA-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Canis familiaris 17996 R-CFA-975389 https://reactome.org/PathwayBrowser/#/R-CFA-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Canis familiaris 17996 R-CFA-975449 https://reactome.org/PathwayBrowser/#/R-CFA-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Canis familiaris 17996 R-DDI-2684901 https://reactome.org/PathwayBrowser/#/R-DDI-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Dictyostelium discoideum 17996 R-DDI-2730692 https://reactome.org/PathwayBrowser/#/R-DDI-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Dictyostelium discoideum 17996 R-DDI-2744228 https://reactome.org/PathwayBrowser/#/R-DDI-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region IEA Dictyostelium discoideum 17996 R-DDI-2744242 https://reactome.org/PathwayBrowser/#/R-DDI-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Dictyostelium discoideum 17996 R-DDI-2744349 https://reactome.org/PathwayBrowser/#/R-DDI-2744349 TTYH1 transports cytosolic Cl- to extracellular region IEA Dictyostelium discoideum 17996 R-DDI-427570 https://reactome.org/PathwayBrowser/#/R-DDI-427570 Group 3 - Selective Cl- transport IEA Dictyostelium discoideum 17996 R-DDI-427666 https://reactome.org/PathwayBrowser/#/R-DDI-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Dictyostelium discoideum 17996 R-DDI-5678863 https://reactome.org/PathwayBrowser/#/R-DDI-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Dictyostelium discoideum 17996 R-DDI-6789031 https://reactome.org/PathwayBrowser/#/R-DDI-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 17996 R-DDI-6789126 https://reactome.org/PathwayBrowser/#/R-DDI-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 17996 R-DDI-76434 https://reactome.org/PathwayBrowser/#/R-DDI-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Dictyostelium discoideum 17996 R-DDI-9011595 https://reactome.org/PathwayBrowser/#/R-DDI-9011595 GSTZ1 dimer dehalogenates DCA IEA Dictyostelium discoideum 17996 R-DDI-9659568 https://reactome.org/PathwayBrowser/#/R-DDI-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Dictyostelium discoideum 17996 R-DME-1237038 https://reactome.org/PathwayBrowser/#/R-DME-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Drosophila melanogaster 17996 R-DME-1247665 https://reactome.org/PathwayBrowser/#/R-DME-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Drosophila melanogaster 17996 R-DME-2022405 https://reactome.org/PathwayBrowser/#/R-DME-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 17996 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 17996 R-DME-2684901 https://reactome.org/PathwayBrowser/#/R-DME-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Drosophila melanogaster 17996 R-DME-2730692 https://reactome.org/PathwayBrowser/#/R-DME-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Drosophila melanogaster 17996 R-DME-2730959 https://reactome.org/PathwayBrowser/#/R-DME-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Drosophila melanogaster 17996 R-DME-2744228 https://reactome.org/PathwayBrowser/#/R-DME-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region IEA Drosophila melanogaster 17996 R-DME-2744242 https://reactome.org/PathwayBrowser/#/R-DME-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Drosophila melanogaster 17996 R-DME-2744349 https://reactome.org/PathwayBrowser/#/R-DME-2744349 TTYH1 transports cytosolic Cl- to extracellular region IEA Drosophila melanogaster 17996 R-DME-2744361 https://reactome.org/PathwayBrowser/#/R-DME-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Drosophila melanogaster 17996 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 17996 R-DME-425482 https://reactome.org/PathwayBrowser/#/R-DME-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Drosophila melanogaster 17996 R-DME-425577 https://reactome.org/PathwayBrowser/#/R-DME-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Drosophila melanogaster 17996 R-DME-426086 https://reactome.org/PathwayBrowser/#/R-DME-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Drosophila melanogaster 17996 R-DME-426130 https://reactome.org/PathwayBrowser/#/R-DME-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 17996 R-DME-426155 https://reactome.org/PathwayBrowser/#/R-DME-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Drosophila melanogaster 17996 R-DME-427570 https://reactome.org/PathwayBrowser/#/R-DME-427570 Group 3 - Selective Cl- transport IEA Drosophila melanogaster 17996 R-DME-427666 https://reactome.org/PathwayBrowser/#/R-DME-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Drosophila melanogaster 17996 R-DME-429594 https://reactome.org/PathwayBrowser/#/R-DME-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 17996 R-DME-444007 https://reactome.org/PathwayBrowser/#/R-DME-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Drosophila melanogaster 17996 R-DME-444008 https://reactome.org/PathwayBrowser/#/R-DME-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 17996 R-DME-444100 https://reactome.org/PathwayBrowser/#/R-DME-444100 PROT mediates L-proline uptake IEA Drosophila melanogaster 17996 R-DME-444120 https://reactome.org/PathwayBrowser/#/R-DME-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 17996 R-DME-451283 https://reactome.org/PathwayBrowser/#/R-DME-451283 kainate receptor binds glutamate IEA Drosophila melanogaster 17996 R-DME-451309 https://reactome.org/PathwayBrowser/#/R-DME-451309 Edited Kainate Receptor binds glutamate IEA Drosophila melanogaster 17996 R-DME-451310 https://reactome.org/PathwayBrowser/#/R-DME-451310 Activation of Edited Kainate receptors IEA Drosophila melanogaster 17996 R-DME-451311 https://reactome.org/PathwayBrowser/#/R-DME-451311 Activation of Ca-permeable Kainate receptors IEA Drosophila melanogaster 17996 R-DME-500708 https://reactome.org/PathwayBrowser/#/R-DME-500708 GRIK3 homomer binds glutamate IEA Drosophila melanogaster 17996 R-DME-500717 https://reactome.org/PathwayBrowser/#/R-DME-500717 Activation of GRIK3 homomer IEA Drosophila melanogaster 17996 R-DME-5678863 https://reactome.org/PathwayBrowser/#/R-DME-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Drosophila melanogaster 17996 R-DME-6789031 https://reactome.org/PathwayBrowser/#/R-DME-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 17996 R-DME-6789126 https://reactome.org/PathwayBrowser/#/R-DME-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 17996 R-DME-76434 https://reactome.org/PathwayBrowser/#/R-DME-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Drosophila melanogaster 17996 R-DME-8941543 https://reactome.org/PathwayBrowser/#/R-DME-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Drosophila melanogaster 17996 R-DME-9011595 https://reactome.org/PathwayBrowser/#/R-DME-9011595 GSTZ1 dimer dehalogenates DCA IEA Drosophila melanogaster 17996 R-DME-975340 https://reactome.org/PathwayBrowser/#/R-DME-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Drosophila melanogaster 17996 R-DME-975389 https://reactome.org/PathwayBrowser/#/R-DME-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Drosophila melanogaster 17996 R-DME-975449 https://reactome.org/PathwayBrowser/#/R-DME-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Drosophila melanogaster 17996 R-DRE-1237038 https://reactome.org/PathwayBrowser/#/R-DRE-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Danio rerio 17996 R-DRE-1247665 https://reactome.org/PathwayBrowser/#/R-DRE-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Danio rerio 17996 R-DRE-2684901 https://reactome.org/PathwayBrowser/#/R-DRE-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Danio rerio 17996 R-DRE-2730692 https://reactome.org/PathwayBrowser/#/R-DRE-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Danio rerio 17996 R-DRE-2744228 https://reactome.org/PathwayBrowser/#/R-DRE-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region IEA Danio rerio 17996 R-DRE-2744242 https://reactome.org/PathwayBrowser/#/R-DRE-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Danio rerio 17996 R-DRE-351987 https://reactome.org/PathwayBrowser/#/R-DRE-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Danio rerio 17996 R-DRE-352029 https://reactome.org/PathwayBrowser/#/R-DRE-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Danio rerio 17996 R-DRE-425482 https://reactome.org/PathwayBrowser/#/R-DRE-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Danio rerio 17996 R-DRE-426086 https://reactome.org/PathwayBrowser/#/R-DRE-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Danio rerio 17996 R-DRE-427666 https://reactome.org/PathwayBrowser/#/R-DRE-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Danio rerio 17996 R-DRE-444007 https://reactome.org/PathwayBrowser/#/R-DRE-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Danio rerio 17996 R-DRE-444008 https://reactome.org/PathwayBrowser/#/R-DRE-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Danio rerio 17996 R-DRE-444120 https://reactome.org/PathwayBrowser/#/R-DRE-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Danio rerio 17996 R-DRE-5678863 https://reactome.org/PathwayBrowser/#/R-DRE-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Danio rerio 17996 R-DRE-76434 https://reactome.org/PathwayBrowser/#/R-DRE-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Danio rerio 17996 R-DRE-8941543 https://reactome.org/PathwayBrowser/#/R-DRE-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Danio rerio 17996 R-DRE-9011595 https://reactome.org/PathwayBrowser/#/R-DRE-9011595 GSTZ1 dimer dehalogenates DCA IEA Danio rerio 17996 R-DRE-975389 https://reactome.org/PathwayBrowser/#/R-DRE-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Danio rerio 17996 R-DRE-975449 https://reactome.org/PathwayBrowser/#/R-DRE-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Danio rerio 17996 R-GGA-1237038 https://reactome.org/PathwayBrowser/#/R-GGA-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Gallus gallus 17996 R-GGA-1247665 https://reactome.org/PathwayBrowser/#/R-GGA-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Gallus gallus 17996 R-GGA-2022405 https://reactome.org/PathwayBrowser/#/R-GGA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 17996 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 17996 R-GGA-2684901 https://reactome.org/PathwayBrowser/#/R-GGA-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Gallus gallus 17996 R-GGA-2730692 https://reactome.org/PathwayBrowser/#/R-GGA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Gallus gallus 17996 R-GGA-2730959 https://reactome.org/PathwayBrowser/#/R-GGA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Gallus gallus 17996 R-GGA-2744228 https://reactome.org/PathwayBrowser/#/R-GGA-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region IEA Gallus gallus 17996 R-GGA-2744242 https://reactome.org/PathwayBrowser/#/R-GGA-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Gallus gallus 17996 R-GGA-2744361 https://reactome.org/PathwayBrowser/#/R-GGA-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Gallus gallus 17996 R-GGA-351987 https://reactome.org/PathwayBrowser/#/R-GGA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Gallus gallus 17996 R-GGA-352029 https://reactome.org/PathwayBrowser/#/R-GGA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Gallus gallus 17996 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 17996 R-GGA-425482 https://reactome.org/PathwayBrowser/#/R-GGA-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Gallus gallus 17996 R-GGA-425577 https://reactome.org/PathwayBrowser/#/R-GGA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Gallus gallus 17996 R-GGA-426086 https://reactome.org/PathwayBrowser/#/R-GGA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Gallus gallus 17996 R-GGA-426155 https://reactome.org/PathwayBrowser/#/R-GGA-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Gallus gallus 17996 R-GGA-427570 https://reactome.org/PathwayBrowser/#/R-GGA-427570 Group 3 - Selective Cl- transport IEA Gallus gallus 17996 R-GGA-427666 https://reactome.org/PathwayBrowser/#/R-GGA-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Gallus gallus 17996 R-GGA-429594 https://reactome.org/PathwayBrowser/#/R-GGA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 17996 R-GGA-444007 https://reactome.org/PathwayBrowser/#/R-GGA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Gallus gallus 17996 R-GGA-444008 https://reactome.org/PathwayBrowser/#/R-GGA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 17996 R-GGA-444100 https://reactome.org/PathwayBrowser/#/R-GGA-444100 PROT mediates L-proline uptake IEA Gallus gallus 17996 R-GGA-444120 https://reactome.org/PathwayBrowser/#/R-GGA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 17996 R-GGA-451283 https://reactome.org/PathwayBrowser/#/R-GGA-451283 kainate receptor binds glutamate IEA Gallus gallus 17996 R-GGA-451309 https://reactome.org/PathwayBrowser/#/R-GGA-451309 Edited Kainate Receptor binds glutamate IEA Gallus gallus 17996 R-GGA-451310 https://reactome.org/PathwayBrowser/#/R-GGA-451310 Activation of Edited Kainate receptors IEA Gallus gallus 17996 R-GGA-451311 https://reactome.org/PathwayBrowser/#/R-GGA-451311 Activation of Ca-permeable Kainate receptors IEA Gallus gallus 17996 R-GGA-500708 https://reactome.org/PathwayBrowser/#/R-GGA-500708 GRIK3 homomer binds glutamate IEA Gallus gallus 17996 R-GGA-500717 https://reactome.org/PathwayBrowser/#/R-GGA-500717 Activation of GRIK3 homomer IEA Gallus gallus 17996 R-GGA-5678863 https://reactome.org/PathwayBrowser/#/R-GGA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Gallus gallus 17996 R-GGA-6789031 https://reactome.org/PathwayBrowser/#/R-GGA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 17996 R-GGA-6789126 https://reactome.org/PathwayBrowser/#/R-GGA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 17996 R-GGA-76434 https://reactome.org/PathwayBrowser/#/R-GGA-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Gallus gallus 17996 R-GGA-8941543 https://reactome.org/PathwayBrowser/#/R-GGA-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Gallus gallus 17996 R-GGA-9011595 https://reactome.org/PathwayBrowser/#/R-GGA-9011595 GSTZ1 dimer dehalogenates DCA IEA Gallus gallus 17996 R-GGA-9659568 https://reactome.org/PathwayBrowser/#/R-GGA-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Gallus gallus 17996 R-GGA-975340 https://reactome.org/PathwayBrowser/#/R-GGA-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Gallus gallus 17996 R-GGA-975389 https://reactome.org/PathwayBrowser/#/R-GGA-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Gallus gallus 17996 R-GGA-975449 https://reactome.org/PathwayBrowser/#/R-GGA-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Gallus gallus 17996 R-HSA-1237038 https://reactome.org/PathwayBrowser/#/R-HSA-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- TAS Homo sapiens 17996 R-HSA-1247665 https://reactome.org/PathwayBrowser/#/R-HSA-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- TAS Homo sapiens 17996 R-HSA-2022405 https://reactome.org/PathwayBrowser/#/R-HSA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 17996 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 17996 R-HSA-2684901 https://reactome.org/PathwayBrowser/#/R-HSA-2684901 ANOs transport cytosolic Cl- to extracellular region TAS Homo sapiens 17996 R-HSA-2730692 https://reactome.org/PathwayBrowser/#/R-HSA-2730692 CLCN4/5/6 exchange Cl- for H+ TAS Homo sapiens 17996 R-HSA-2730959 https://reactome.org/PathwayBrowser/#/R-HSA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ TAS Homo sapiens 17996 R-HSA-2731002 https://reactome.org/PathwayBrowser/#/R-HSA-2731002 CLCN3 exchanges Cl- for H+ IEA Homo sapiens 17996 R-HSA-2744228 https://reactome.org/PathwayBrowser/#/R-HSA-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region TAS Homo sapiens 17996 R-HSA-2744242 https://reactome.org/PathwayBrowser/#/R-HSA-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region TAS Homo sapiens 17996 R-HSA-2744349 https://reactome.org/PathwayBrowser/#/R-HSA-2744349 TTYH1 transports cytosolic Cl- to extracellular region TAS Homo sapiens 17996 R-HSA-2744361 https://reactome.org/PathwayBrowser/#/R-HSA-2744361 BESTs transport cytosolic Cl- to extracellular region TAS Homo sapiens 17996 R-HSA-351987 https://reactome.org/PathwayBrowser/#/R-HSA-351987 SLC6A6-mediated uptake of taurine and beta-alanine TAS Homo sapiens 17996 R-HSA-352029 https://reactome.org/PathwayBrowser/#/R-HSA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine TAS Homo sapiens 17996 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-425482 https://reactome.org/PathwayBrowser/#/R-HSA-425482 SLC4A1,2,3 exchanges HCO3- for Cl- TAS Homo sapiens 17996 R-HSA-425577 https://reactome.org/PathwayBrowser/#/R-HSA-425577 Na+-driven Cl-/HCO3- exchanger transport TAS Homo sapiens 17996 R-HSA-426086 https://reactome.org/PathwayBrowser/#/R-HSA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-426130 https://reactome.org/PathwayBrowser/#/R-HSA-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-426155 https://reactome.org/PathwayBrowser/#/R-HSA-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region TAS Homo sapiens 17996 R-HSA-427570 https://reactome.org/PathwayBrowser/#/R-HSA-427570 Group 3 - Selective Cl- transport TAS Homo sapiens 17996 R-HSA-427666 https://reactome.org/PathwayBrowser/#/R-HSA-427666 SLC26A3,6 exchange Cl- for HCO3- TAS Homo sapiens 17996 R-HSA-429594 https://reactome.org/PathwayBrowser/#/R-HSA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-432034 https://reactome.org/PathwayBrowser/#/R-HSA-432034 Aquaporin-6 passively transports anions into vesicles IEA Homo sapiens 17996 R-HSA-432036 https://reactome.org/PathwayBrowser/#/R-HSA-432036 Aquaporin-6 passively transports anions out of vesicles IEA Homo sapiens 17996 R-HSA-444007 https://reactome.org/PathwayBrowser/#/R-HSA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport TAS Homo sapiens 17996 R-HSA-444008 https://reactome.org/PathwayBrowser/#/R-HSA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-444100 https://reactome.org/PathwayBrowser/#/R-HSA-444100 PROT mediates L-proline uptake TAS Homo sapiens 17996 R-HSA-444120 https://reactome.org/PathwayBrowser/#/R-HSA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-451283 https://reactome.org/PathwayBrowser/#/R-HSA-451283 kainate receptor binds glutamate TAS Homo sapiens 17996 R-HSA-451309 https://reactome.org/PathwayBrowser/#/R-HSA-451309 Edited Kainate Receptor binds glutamate TAS Homo sapiens 17996 R-HSA-451310 https://reactome.org/PathwayBrowser/#/R-HSA-451310 Activation of Edited Kainate receptors TAS Homo sapiens 17996 R-HSA-451311 https://reactome.org/PathwayBrowser/#/R-HSA-451311 Activation of Ca-permeable Kainate receptors TAS Homo sapiens 17996 R-HSA-500708 https://reactome.org/PathwayBrowser/#/R-HSA-500708 GRIK3 homomer binds glutamate TAS Homo sapiens 17996 R-HSA-500717 https://reactome.org/PathwayBrowser/#/R-HSA-500717 Activation of GRIK3 homomer TAS Homo sapiens 17996 R-HSA-5623588 https://reactome.org/PathwayBrowser/#/R-HSA-5623588 Defective SLC12A1 does not cotransport Na+, K+, 2Cl- from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-5623705 https://reactome.org/PathwayBrowser/#/R-HSA-5623705 Defective SLC12A3 does not cotransport Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-5623806 https://reactome.org/PathwayBrowser/#/R-HSA-5623806 Defective SLC12A6 does not cotransport K+, Cl- from cytosol to extracellular region TAS Homo sapiens 17996 R-HSA-5627737 https://reactome.org/PathwayBrowser/#/R-HSA-5627737 SLC26A3 does not exchange Cl- for HCO3- TAS Homo sapiens 17996 R-HSA-5656248 https://reactome.org/PathwayBrowser/#/R-HSA-5656248 Defective SLC4A1 does not exchange Cl- for HCO3- (in erythrocytes) TAS Homo sapiens 17996 R-HSA-5658483 https://reactome.org/PathwayBrowser/#/R-HSA-5658483 Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-5660840 https://reactome.org/PathwayBrowser/#/R-HSA-5660840 Defective SLC6A5 does not cotransport Gly, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-5678822 https://reactome.org/PathwayBrowser/#/R-HSA-5678822 Defective CFTR does not transport Cl- from cytosol to extracellular region TAS Homo sapiens 17996 R-HSA-5678863 https://reactome.org/PathwayBrowser/#/R-HSA-5678863 CFTR transports Cl- from cytosol to extracellular region TAS Homo sapiens 17996 R-HSA-5678992 https://reactome.org/PathwayBrowser/#/R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region TAS Homo sapiens 17996 R-HSA-6789031 https://reactome.org/PathwayBrowser/#/R-HSA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 17996 R-HSA-6789126 https://reactome.org/PathwayBrowser/#/R-HSA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 17996 R-HSA-76434 https://reactome.org/PathwayBrowser/#/R-HSA-76434 Dehalogenation of carbon tetrachloride to form a free radical TAS Homo sapiens 17996 R-HSA-8941543 https://reactome.org/PathwayBrowser/#/R-HSA-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region TAS Homo sapiens 17996 R-HSA-9011595 https://reactome.org/PathwayBrowser/#/R-HSA-9011595 GSTZ1 dimer dehalogenates DCA TAS Homo sapiens 17996 R-HSA-9625540 https://reactome.org/PathwayBrowser/#/R-HSA-9625540 Cys-sulfenyl chloride is converted to Cys-sulfenic acid TAS Homo sapiens 17996 R-HSA-9659568 https://reactome.org/PathwayBrowser/#/R-HSA-9659568 ANO1 transports cytosolic Cl- to extracellular region TAS Homo sapiens 17996 R-HSA-9663354 https://reactome.org/PathwayBrowser/#/R-HSA-9663354 SLC26A5 (prestin) changes conformation in response to depolarization IEA Homo sapiens 17996 R-HSA-9712204 https://reactome.org/PathwayBrowser/#/R-HSA-9712204 ANO2:Ca2+ translocates Cl- from the cytosol to the extracellular region IEA Homo sapiens 17996 R-HSA-975340 https://reactome.org/PathwayBrowser/#/R-HSA-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol TAS Homo sapiens 17996 R-HSA-975389 https://reactome.org/PathwayBrowser/#/R-HSA-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol TAS Homo sapiens 17996 R-HSA-975449 https://reactome.org/PathwayBrowser/#/R-HSA-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol TAS Homo sapiens 17996 R-HSA-9793564 https://reactome.org/PathwayBrowser/#/R-HSA-9793564 Cipro HCl dissolves TAS Homo sapiens 17996 R-HSA-9863531 https://reactome.org/PathwayBrowser/#/R-HSA-9863531 GS-MCA spontaneously hydrolyzes TAS Homo sapiens 17996 R-MMU-1237038 https://reactome.org/PathwayBrowser/#/R-MMU-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Mus musculus 17996 R-MMU-1247665 https://reactome.org/PathwayBrowser/#/R-MMU-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Mus musculus 17996 R-MMU-2022405 https://reactome.org/PathwayBrowser/#/R-MMU-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 17996 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 17996 R-MMU-2684901 https://reactome.org/PathwayBrowser/#/R-MMU-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Mus musculus 17996 R-MMU-2730692 https://reactome.org/PathwayBrowser/#/R-MMU-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Mus musculus 17996 R-MMU-2730951 https://reactome.org/PathwayBrowser/#/R-MMU-2730951 Clcn3 exchanges Cl- for H+ TAS Mus musculus 17996 R-MMU-2730959 https://reactome.org/PathwayBrowser/#/R-MMU-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Mus musculus 17996 R-MMU-2744228 https://reactome.org/PathwayBrowser/#/R-MMU-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region IEA Mus musculus 17996 R-MMU-2744242 https://reactome.org/PathwayBrowser/#/R-MMU-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Mus musculus 17996 R-MMU-2744349 https://reactome.org/PathwayBrowser/#/R-MMU-2744349 TTYH1 transports cytosolic Cl- to extracellular region IEA Mus musculus 17996 R-MMU-2744361 https://reactome.org/PathwayBrowser/#/R-MMU-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Mus musculus 17996 R-MMU-351987 https://reactome.org/PathwayBrowser/#/R-MMU-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Mus musculus 17996 R-MMU-352029 https://reactome.org/PathwayBrowser/#/R-MMU-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Mus musculus 17996 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 17996 R-MMU-425482 https://reactome.org/PathwayBrowser/#/R-MMU-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Mus musculus 17996 R-MMU-425577 https://reactome.org/PathwayBrowser/#/R-MMU-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Mus musculus 17996 R-MMU-426086 https://reactome.org/PathwayBrowser/#/R-MMU-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Mus musculus 17996 R-MMU-426130 https://reactome.org/PathwayBrowser/#/R-MMU-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 17996 R-MMU-426155 https://reactome.org/PathwayBrowser/#/R-MMU-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Mus musculus 17996 R-MMU-427570 https://reactome.org/PathwayBrowser/#/R-MMU-427570 Group 3 - Selective Cl- transport IEA Mus musculus 17996 R-MMU-427666 https://reactome.org/PathwayBrowser/#/R-MMU-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Mus musculus 17996 R-MMU-429594 https://reactome.org/PathwayBrowser/#/R-MMU-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 17996 R-MMU-444007 https://reactome.org/PathwayBrowser/#/R-MMU-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Mus musculus 17996 R-MMU-444008 https://reactome.org/PathwayBrowser/#/R-MMU-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 17996 R-MMU-444100 https://reactome.org/PathwayBrowser/#/R-MMU-444100 PROT mediates L-proline uptake IEA Mus musculus 17996 R-MMU-444120 https://reactome.org/PathwayBrowser/#/R-MMU-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 17996 R-MMU-451283 https://reactome.org/PathwayBrowser/#/R-MMU-451283 kainate receptor binds glutamate IEA Mus musculus 17996 R-MMU-451309 https://reactome.org/PathwayBrowser/#/R-MMU-451309 Edited Kainate Receptor binds glutamate IEA Mus musculus 17996 R-MMU-451310 https://reactome.org/PathwayBrowser/#/R-MMU-451310 Activation of Edited Kainate receptors IEA Mus musculus 17996 R-MMU-451311 https://reactome.org/PathwayBrowser/#/R-MMU-451311 Activation of Ca-permeable Kainate receptors IEA Mus musculus 17996 R-MMU-500708 https://reactome.org/PathwayBrowser/#/R-MMU-500708 GRIK3 homomer binds glutamate IEA Mus musculus 17996 R-MMU-500717 https://reactome.org/PathwayBrowser/#/R-MMU-500717 Activation of GRIK3 homomer IEA Mus musculus 17996 R-MMU-5678863 https://reactome.org/PathwayBrowser/#/R-MMU-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Mus musculus 17996 R-MMU-6789031 https://reactome.org/PathwayBrowser/#/R-MMU-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 17996 R-MMU-6789126 https://reactome.org/PathwayBrowser/#/R-MMU-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 17996 R-MMU-76434 https://reactome.org/PathwayBrowser/#/R-MMU-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Mus musculus 17996 R-MMU-8941543 https://reactome.org/PathwayBrowser/#/R-MMU-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Mus musculus 17996 R-MMU-9011595 https://reactome.org/PathwayBrowser/#/R-MMU-9011595 GSTZ1 dimer dehalogenates DCA IEA Mus musculus 17996 R-MMU-9659568 https://reactome.org/PathwayBrowser/#/R-MMU-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Mus musculus 17996 R-MMU-9663359 https://reactome.org/PathwayBrowser/#/R-MMU-9663359 Slc26a5 changes conformation in response to depolarization TAS Mus musculus 17996 R-MMU-9714186 https://reactome.org/PathwayBrowser/#/R-MMU-9714186 Ano2 dimer:Ca2+ translocates Cl- from the cytosol to the extracellular region TAS Mus musculus 17996 R-MMU-975340 https://reactome.org/PathwayBrowser/#/R-MMU-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Mus musculus 17996 R-MMU-975389 https://reactome.org/PathwayBrowser/#/R-MMU-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Mus musculus 17996 R-MMU-975449 https://reactome.org/PathwayBrowser/#/R-MMU-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Mus musculus 17996 R-PFA-351987 https://reactome.org/PathwayBrowser/#/R-PFA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Plasmodium falciparum 17996 R-PFA-352029 https://reactome.org/PathwayBrowser/#/R-PFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Plasmodium falciparum 17996 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 17996 R-PFA-444007 https://reactome.org/PathwayBrowser/#/R-PFA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Plasmodium falciparum 17996 R-PFA-444008 https://reactome.org/PathwayBrowser/#/R-PFA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 17996 R-PFA-444100 https://reactome.org/PathwayBrowser/#/R-PFA-444100 PROT mediates L-proline uptake IEA Plasmodium falciparum 17996 R-PFA-444120 https://reactome.org/PathwayBrowser/#/R-PFA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 17996 R-PFA-5678863 https://reactome.org/PathwayBrowser/#/R-PFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Plasmodium falciparum 17996 R-RNO-1237038 https://reactome.org/PathwayBrowser/#/R-RNO-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Rattus norvegicus 17996 R-RNO-1247665 https://reactome.org/PathwayBrowser/#/R-RNO-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Rattus norvegicus 17996 R-RNO-2022405 https://reactome.org/PathwayBrowser/#/R-RNO-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 17996 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 17996 R-RNO-2684901 https://reactome.org/PathwayBrowser/#/R-RNO-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Rattus norvegicus 17996 R-RNO-2730692 https://reactome.org/PathwayBrowser/#/R-RNO-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Rattus norvegicus 17996 R-RNO-2730959 https://reactome.org/PathwayBrowser/#/R-RNO-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Rattus norvegicus 17996 R-RNO-2744228 https://reactome.org/PathwayBrowser/#/R-RNO-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region IEA Rattus norvegicus 17996 R-RNO-2744242 https://reactome.org/PathwayBrowser/#/R-RNO-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Rattus norvegicus 17996 R-RNO-2744349 https://reactome.org/PathwayBrowser/#/R-RNO-2744349 TTYH1 transports cytosolic Cl- to extracellular region IEA Rattus norvegicus 17996 R-RNO-2744361 https://reactome.org/PathwayBrowser/#/R-RNO-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Rattus norvegicus 17996 R-RNO-351987 https://reactome.org/PathwayBrowser/#/R-RNO-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Rattus norvegicus 17996 R-RNO-352029 https://reactome.org/PathwayBrowser/#/R-RNO-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Rattus norvegicus 17996 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 17996 R-RNO-425482 https://reactome.org/PathwayBrowser/#/R-RNO-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Rattus norvegicus 17996 R-RNO-425577 https://reactome.org/PathwayBrowser/#/R-RNO-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Rattus norvegicus 17996 R-RNO-426086 https://reactome.org/PathwayBrowser/#/R-RNO-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Rattus norvegicus 17996 R-RNO-426130 https://reactome.org/PathwayBrowser/#/R-RNO-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 17996 R-RNO-426155 https://reactome.org/PathwayBrowser/#/R-RNO-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Rattus norvegicus 17996 R-RNO-427570 https://reactome.org/PathwayBrowser/#/R-RNO-427570 Group 3 - Selective Cl- transport IEA Rattus norvegicus 17996 R-RNO-427666 https://reactome.org/PathwayBrowser/#/R-RNO-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Rattus norvegicus 17996 R-RNO-429594 https://reactome.org/PathwayBrowser/#/R-RNO-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 17996 R-RNO-444007 https://reactome.org/PathwayBrowser/#/R-RNO-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Rattus norvegicus 17996 R-RNO-444008 https://reactome.org/PathwayBrowser/#/R-RNO-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 17996 R-RNO-444100 https://reactome.org/PathwayBrowser/#/R-RNO-444100 PROT mediates L-proline uptake IEA Rattus norvegicus 17996 R-RNO-444120 https://reactome.org/PathwayBrowser/#/R-RNO-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 17996 R-RNO-451283 https://reactome.org/PathwayBrowser/#/R-RNO-451283 kainate receptor binds glutamate IEA Rattus norvegicus 17996 R-RNO-451309 https://reactome.org/PathwayBrowser/#/R-RNO-451309 Edited Kainate Receptor binds glutamate IEA Rattus norvegicus 17996 R-RNO-451310 https://reactome.org/PathwayBrowser/#/R-RNO-451310 Activation of Edited Kainate receptors IEA Rattus norvegicus 17996 R-RNO-451311 https://reactome.org/PathwayBrowser/#/R-RNO-451311 Activation of Ca-permeable Kainate receptors IEA Rattus norvegicus 17996 R-RNO-500708 https://reactome.org/PathwayBrowser/#/R-RNO-500708 GRIK3 homomer binds glutamate IEA Rattus norvegicus 17996 R-RNO-5678863 https://reactome.org/PathwayBrowser/#/R-RNO-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Rattus norvegicus 17996 R-RNO-6789031 https://reactome.org/PathwayBrowser/#/R-RNO-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 17996 R-RNO-6789126 https://reactome.org/PathwayBrowser/#/R-RNO-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 17996 R-RNO-76434 https://reactome.org/PathwayBrowser/#/R-RNO-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Rattus norvegicus 17996 R-RNO-879862 https://reactome.org/PathwayBrowser/#/R-RNO-879862 Passive Transport of Anions into Vesicles by Aquaporin-6 (rat) TAS Rattus norvegicus 17996 R-RNO-879863 https://reactome.org/PathwayBrowser/#/R-RNO-879863 Passive Transport of Anions out of Vesicles by Aquaporin-6 (rat) TAS Rattus norvegicus 17996 R-RNO-8941543 https://reactome.org/PathwayBrowser/#/R-RNO-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Rattus norvegicus 17996 R-RNO-9011595 https://reactome.org/PathwayBrowser/#/R-RNO-9011595 GSTZ1 dimer dehalogenates DCA IEA Rattus norvegicus 17996 R-RNO-9659568 https://reactome.org/PathwayBrowser/#/R-RNO-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Rattus norvegicus 17996 R-RNO-9667710 https://reactome.org/PathwayBrowser/#/R-RNO-9667710 Slc26a5 changes conformation in response to depolarization TAS Rattus norvegicus 17996 R-RNO-975340 https://reactome.org/PathwayBrowser/#/R-RNO-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Rattus norvegicus 17996 R-RNO-975389 https://reactome.org/PathwayBrowser/#/R-RNO-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Rattus norvegicus 17996 R-RNO-975449 https://reactome.org/PathwayBrowser/#/R-RNO-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Rattus norvegicus 17996 R-SCE-2684901 https://reactome.org/PathwayBrowser/#/R-SCE-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Saccharomyces cerevisiae 17996 R-SCE-2730692 https://reactome.org/PathwayBrowser/#/R-SCE-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Saccharomyces cerevisiae 17996 R-SCE-427570 https://reactome.org/PathwayBrowser/#/R-SCE-427570 Group 3 - Selective Cl- transport IEA Saccharomyces cerevisiae 17996 R-SCE-427666 https://reactome.org/PathwayBrowser/#/R-SCE-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Saccharomyces cerevisiae 17996 R-SCE-9659568 https://reactome.org/PathwayBrowser/#/R-SCE-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Saccharomyces cerevisiae 17996 R-SPO-2684901 https://reactome.org/PathwayBrowser/#/R-SPO-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Schizosaccharomyces pombe 17996 R-SPO-2730692 https://reactome.org/PathwayBrowser/#/R-SPO-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Schizosaccharomyces pombe 17996 R-SPO-427570 https://reactome.org/PathwayBrowser/#/R-SPO-427570 Group 3 - Selective Cl- transport IEA Schizosaccharomyces pombe 17996 R-SPO-427666 https://reactome.org/PathwayBrowser/#/R-SPO-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Schizosaccharomyces pombe 17996 R-SPO-9659568 https://reactome.org/PathwayBrowser/#/R-SPO-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Schizosaccharomyces pombe 17996 R-SSC-1237038 https://reactome.org/PathwayBrowser/#/R-SSC-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Sus scrofa 17996 R-SSC-1247665 https://reactome.org/PathwayBrowser/#/R-SSC-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Sus scrofa 17996 R-SSC-2022405 https://reactome.org/PathwayBrowser/#/R-SSC-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 17996 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 17996 R-SSC-2684901 https://reactome.org/PathwayBrowser/#/R-SSC-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Sus scrofa 17996 R-SSC-2730692 https://reactome.org/PathwayBrowser/#/R-SSC-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Sus scrofa 17996 R-SSC-2730959 https://reactome.org/PathwayBrowser/#/R-SSC-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Sus scrofa 17996 R-SSC-2744228 https://reactome.org/PathwayBrowser/#/R-SSC-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region IEA Sus scrofa 17996 R-SSC-2744242 https://reactome.org/PathwayBrowser/#/R-SSC-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Sus scrofa 17996 R-SSC-2744349 https://reactome.org/PathwayBrowser/#/R-SSC-2744349 TTYH1 transports cytosolic Cl- to extracellular region IEA Sus scrofa 17996 R-SSC-2744361 https://reactome.org/PathwayBrowser/#/R-SSC-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Sus scrofa 17996 R-SSC-351987 https://reactome.org/PathwayBrowser/#/R-SSC-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Sus scrofa 17996 R-SSC-352029 https://reactome.org/PathwayBrowser/#/R-SSC-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Sus scrofa 17996 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 17996 R-SSC-425482 https://reactome.org/PathwayBrowser/#/R-SSC-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Sus scrofa 17996 R-SSC-425577 https://reactome.org/PathwayBrowser/#/R-SSC-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Sus scrofa 17996 R-SSC-426086 https://reactome.org/PathwayBrowser/#/R-SSC-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Sus scrofa 17996 R-SSC-426130 https://reactome.org/PathwayBrowser/#/R-SSC-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 17996 R-SSC-426155 https://reactome.org/PathwayBrowser/#/R-SSC-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Sus scrofa 17996 R-SSC-427570 https://reactome.org/PathwayBrowser/#/R-SSC-427570 Group 3 - Selective Cl- transport IEA Sus scrofa 17996 R-SSC-427666 https://reactome.org/PathwayBrowser/#/R-SSC-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Sus scrofa 17996 R-SSC-429594 https://reactome.org/PathwayBrowser/#/R-SSC-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 17996 R-SSC-444007 https://reactome.org/PathwayBrowser/#/R-SSC-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Sus scrofa 17996 R-SSC-444008 https://reactome.org/PathwayBrowser/#/R-SSC-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 17996 R-SSC-444100 https://reactome.org/PathwayBrowser/#/R-SSC-444100 PROT mediates L-proline uptake IEA Sus scrofa 17996 R-SSC-444120 https://reactome.org/PathwayBrowser/#/R-SSC-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 17996 R-SSC-451283 https://reactome.org/PathwayBrowser/#/R-SSC-451283 kainate receptor binds glutamate IEA Sus scrofa 17996 R-SSC-451309 https://reactome.org/PathwayBrowser/#/R-SSC-451309 Edited Kainate Receptor binds glutamate IEA Sus scrofa 17996 R-SSC-451310 https://reactome.org/PathwayBrowser/#/R-SSC-451310 Activation of Edited Kainate receptors IEA Sus scrofa 17996 R-SSC-451311 https://reactome.org/PathwayBrowser/#/R-SSC-451311 Activation of Ca-permeable Kainate receptors IEA Sus scrofa 17996 R-SSC-500708 https://reactome.org/PathwayBrowser/#/R-SSC-500708 GRIK3 homomer binds glutamate IEA Sus scrofa 17996 R-SSC-500717 https://reactome.org/PathwayBrowser/#/R-SSC-500717 Activation of GRIK3 homomer IEA Sus scrofa 17996 R-SSC-5678863 https://reactome.org/PathwayBrowser/#/R-SSC-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Sus scrofa 17996 R-SSC-6789031 https://reactome.org/PathwayBrowser/#/R-SSC-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 17996 R-SSC-6789126 https://reactome.org/PathwayBrowser/#/R-SSC-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 17996 R-SSC-76434 https://reactome.org/PathwayBrowser/#/R-SSC-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Sus scrofa 17996 R-SSC-8941543 https://reactome.org/PathwayBrowser/#/R-SSC-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Sus scrofa 17996 R-SSC-9011595 https://reactome.org/PathwayBrowser/#/R-SSC-9011595 GSTZ1 dimer dehalogenates DCA IEA Sus scrofa 17996 R-SSC-9659568 https://reactome.org/PathwayBrowser/#/R-SSC-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Sus scrofa 17996 R-SSC-975340 https://reactome.org/PathwayBrowser/#/R-SSC-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Sus scrofa 17996 R-SSC-975389 https://reactome.org/PathwayBrowser/#/R-SSC-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Sus scrofa 17996 R-SSC-975449 https://reactome.org/PathwayBrowser/#/R-SSC-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Sus scrofa 17996 R-XTR-1237038 https://reactome.org/PathwayBrowser/#/R-XTR-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Xenopus tropicalis 17996 R-XTR-1247665 https://reactome.org/PathwayBrowser/#/R-XTR-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Xenopus tropicalis 17996 R-XTR-2022405 https://reactome.org/PathwayBrowser/#/R-XTR-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 17996 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 17996 R-XTR-2684901 https://reactome.org/PathwayBrowser/#/R-XTR-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Xenopus tropicalis 17996 R-XTR-2730692 https://reactome.org/PathwayBrowser/#/R-XTR-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Xenopus tropicalis 17996 R-XTR-2730959 https://reactome.org/PathwayBrowser/#/R-XTR-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Xenopus tropicalis 17996 R-XTR-2744228 https://reactome.org/PathwayBrowser/#/R-XTR-2744228 CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region IEA Xenopus tropicalis 17996 R-XTR-2744242 https://reactome.org/PathwayBrowser/#/R-XTR-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Xenopus tropicalis 17996 R-XTR-2744349 https://reactome.org/PathwayBrowser/#/R-XTR-2744349 TTYH1 transports cytosolic Cl- to extracellular region IEA Xenopus tropicalis 17996 R-XTR-2744361 https://reactome.org/PathwayBrowser/#/R-XTR-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Xenopus tropicalis 17996 R-XTR-351987 https://reactome.org/PathwayBrowser/#/R-XTR-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Xenopus tropicalis 17996 R-XTR-352029 https://reactome.org/PathwayBrowser/#/R-XTR-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Xenopus tropicalis 17996 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 17996 R-XTR-425482 https://reactome.org/PathwayBrowser/#/R-XTR-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Xenopus tropicalis 17996 R-XTR-425577 https://reactome.org/PathwayBrowser/#/R-XTR-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Xenopus tropicalis 17996 R-XTR-426086 https://reactome.org/PathwayBrowser/#/R-XTR-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Xenopus tropicalis 17996 R-XTR-426130 https://reactome.org/PathwayBrowser/#/R-XTR-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 17996 R-XTR-426155 https://reactome.org/PathwayBrowser/#/R-XTR-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Xenopus tropicalis 17996 R-XTR-427570 https://reactome.org/PathwayBrowser/#/R-XTR-427570 Group 3 - Selective Cl- transport IEA Xenopus tropicalis 17996 R-XTR-427666 https://reactome.org/PathwayBrowser/#/R-XTR-427666 SLC26A3,6 exchange Cl- for HCO3- IEA Xenopus tropicalis 17996 R-XTR-429594 https://reactome.org/PathwayBrowser/#/R-XTR-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 17996 R-XTR-444007 https://reactome.org/PathwayBrowser/#/R-XTR-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Xenopus tropicalis 17996 R-XTR-444008 https://reactome.org/PathwayBrowser/#/R-XTR-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 17996 R-XTR-444100 https://reactome.org/PathwayBrowser/#/R-XTR-444100 PROT mediates L-proline uptake IEA Xenopus tropicalis 17996 R-XTR-444120 https://reactome.org/PathwayBrowser/#/R-XTR-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 17996 R-XTR-500708 https://reactome.org/PathwayBrowser/#/R-XTR-500708 GRIK3 homomer binds glutamate IEA Xenopus tropicalis 17996 R-XTR-500717 https://reactome.org/PathwayBrowser/#/R-XTR-500717 Activation of GRIK3 homomer IEA Xenopus tropicalis 17996 R-XTR-5678863 https://reactome.org/PathwayBrowser/#/R-XTR-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Xenopus tropicalis 17996 R-XTR-76434 https://reactome.org/PathwayBrowser/#/R-XTR-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Xenopus tropicalis 17996 R-XTR-9011595 https://reactome.org/PathwayBrowser/#/R-XTR-9011595 GSTZ1 dimer dehalogenates DCA IEA Xenopus tropicalis 17996 R-XTR-9659568 https://reactome.org/PathwayBrowser/#/R-XTR-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Xenopus tropicalis 17996 R-XTR-975340 https://reactome.org/PathwayBrowser/#/R-XTR-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Xenopus tropicalis 17996 R-XTR-975389 https://reactome.org/PathwayBrowser/#/R-XTR-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Xenopus tropicalis 17996 R-XTR-975449 https://reactome.org/PathwayBrowser/#/R-XTR-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Xenopus tropicalis 17998 R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 17998 R-BTA-196060 https://reactome.org/PathwayBrowser/#/R-BTA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Bos taurus 17998 R-CEL-196060 https://reactome.org/PathwayBrowser/#/R-CEL-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Caenorhabditis elegans 17998 R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 17998 R-CFA-196060 https://reactome.org/PathwayBrowser/#/R-CFA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Canis familiaris 17998 R-DDI-196060 https://reactome.org/PathwayBrowser/#/R-DDI-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Dictyostelium discoideum 17998 R-DME-196060 https://reactome.org/PathwayBrowser/#/R-DME-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Drosophila melanogaster 17998 R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 17998 R-DRE-196060 https://reactome.org/PathwayBrowser/#/R-DRE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Danio rerio 17998 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 17998 R-GGA-196060 https://reactome.org/PathwayBrowser/#/R-GGA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Gallus gallus 17998 R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 17998 R-HSA-196060 https://reactome.org/PathwayBrowser/#/R-HSA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol TAS Homo sapiens 17998 R-HSA-196125 https://reactome.org/PathwayBrowser/#/R-HSA-196125 Translocation of isocaproaldehyde from the mitochondrial matrix to the cytosol TAS Homo sapiens 17998 R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 17998 R-MMU-196060 https://reactome.org/PathwayBrowser/#/R-MMU-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Mus musculus 17998 R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 17998 R-RNO-196060 https://reactome.org/PathwayBrowser/#/R-RNO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Rattus norvegicus 17998 R-SCE-196060 https://reactome.org/PathwayBrowser/#/R-SCE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Saccharomyces cerevisiae 17998 R-SPO-196060 https://reactome.org/PathwayBrowser/#/R-SPO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Schizosaccharomyces pombe 17998 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 17998 R-SSC-196060 https://reactome.org/PathwayBrowser/#/R-SSC-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Sus scrofa 17998 R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 17998 R-XTR-196060 https://reactome.org/PathwayBrowser/#/R-XTR-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Xenopus tropicalis 18005 R-BTA-2160492 https://reactome.org/PathwayBrowser/#/R-BTA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Bos taurus 18005 R-CFA-2160492 https://reactome.org/PathwayBrowser/#/R-CFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Canis familiaris 18005 R-DDI-2160492 https://reactome.org/PathwayBrowser/#/R-DDI-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Dictyostelium discoideum 18005 R-HSA-2160492 https://reactome.org/PathwayBrowser/#/R-HSA-2160492 IL4I1:FAD oxidises L-Phe to kPPV TAS Homo sapiens 18005 R-MMU-2160492 https://reactome.org/PathwayBrowser/#/R-MMU-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Mus musculus 18005 R-PFA-2160492 https://reactome.org/PathwayBrowser/#/R-PFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Plasmodium falciparum 18005 R-RNO-2160492 https://reactome.org/PathwayBrowser/#/R-RNO-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Rattus norvegicus 18005 R-SSC-2160492 https://reactome.org/PathwayBrowser/#/R-SSC-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Sus scrofa 18005 R-XTR-2160492 https://reactome.org/PathwayBrowser/#/R-XTR-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Xenopus tropicalis 18009 R-BTA-1236967 https://reactome.org/PathwayBrowser/#/R-BTA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Bos taurus 18009 R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 18009 R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 18009 R-BTA-194674 https://reactome.org/PathwayBrowser/#/R-BTA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Bos taurus 18009 R-BTA-2046088 https://reactome.org/PathwayBrowser/#/R-BTA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Bos taurus 18009 R-BTA-2046090 https://reactome.org/PathwayBrowser/#/R-BTA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 18009 R-BTA-2046094 https://reactome.org/PathwayBrowser/#/R-BTA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Bos taurus 18009 R-BTA-2046100 https://reactome.org/PathwayBrowser/#/R-BTA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Bos taurus 18009 R-BTA-209921 https://reactome.org/PathwayBrowser/#/R-BTA-209921 Monoiodinated tyrosine can be deiodinated IEA Bos taurus 18009 R-BTA-209960 https://reactome.org/PathwayBrowser/#/R-BTA-209960 Diiodinated tyrosine can be deiodinated IEA Bos taurus 18009 R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 18009 R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 18009 R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 18009 R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 18009 R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 18009 R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 18009 R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 18009 R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 18009 R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 18009 R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 18009 R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 18009 R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 18009 R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 18009 R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 18009 R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 18009 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 18009 R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 18009 R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 18009 R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 18009 R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 18009 R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 18009 R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 18009 R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Bos taurus 18009 R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 18009 R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 18009 R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 18009 R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 18009 R-BTA-350901 https://reactome.org/PathwayBrowser/#/R-BTA-350901 Iodide is organified IEA Bos taurus 18009 R-BTA-389550 https://reactome.org/PathwayBrowser/#/R-BTA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 18009 R-BTA-389826 https://reactome.org/PathwayBrowser/#/R-BTA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Bos taurus 18009 R-BTA-5623643 https://reactome.org/PathwayBrowser/#/R-BTA-5623643 RDH13 reduces atRAL to atROL IEA Bos taurus 18009 R-BTA-5693347 https://reactome.org/PathwayBrowser/#/R-BTA-5693347 CRYM reduces P2C to PPCA IEA Bos taurus 18009 R-BTA-5693681 https://reactome.org/PathwayBrowser/#/R-BTA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Bos taurus 18009 R-BTA-6786720 https://reactome.org/PathwayBrowser/#/R-BTA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Bos taurus 18009 R-BTA-6809810 https://reactome.org/PathwayBrowser/#/R-BTA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Bos taurus 18009 R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 18009 R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 18009 R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 18009 R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 18009 R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 18009 R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 18009 R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 18009 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 18009 R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 18009 R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 18009 R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 18009 R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 18009 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 18009 R-CEL-2046088 https://reactome.org/PathwayBrowser/#/R-CEL-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Caenorhabditis elegans 18009 R-CEL-2046094 https://reactome.org/PathwayBrowser/#/R-CEL-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Caenorhabditis elegans 18009 R-CEL-209921 https://reactome.org/PathwayBrowser/#/R-CEL-209921 Monoiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 18009 R-CEL-209960 https://reactome.org/PathwayBrowser/#/R-CEL-209960 Diiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 18009 R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 18009 R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 18009 R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 18009 R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 18009 R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 18009 R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 18009 R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 18009 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 18009 R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 18009 R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 18009 R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 18009 R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 18009 R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 18009 R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 18009 R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 18009 R-CEL-350901 https://reactome.org/PathwayBrowser/#/R-CEL-350901 Iodide is organified IEA Caenorhabditis elegans 18009 R-CEL-389550 https://reactome.org/PathwayBrowser/#/R-CEL-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 18009 R-CEL-5623643 https://reactome.org/PathwayBrowser/#/R-CEL-5623643 RDH13 reduces atRAL to atROL IEA Caenorhabditis elegans 18009 R-CEL-5693681 https://reactome.org/PathwayBrowser/#/R-CEL-5693681 DUOX1,2 reduce O2 to H2O2 IEA Caenorhabditis elegans 18009 R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 18009 R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 18009 R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 18009 R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 18009 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 18009 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 18009 R-CFA-1236967 https://reactome.org/PathwayBrowser/#/R-CFA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Canis familiaris 18009 R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 18009 R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 18009 R-CFA-194674 https://reactome.org/PathwayBrowser/#/R-CFA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Canis familiaris 18009 R-CFA-2046088 https://reactome.org/PathwayBrowser/#/R-CFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Canis familiaris 18009 R-CFA-2046090 https://reactome.org/PathwayBrowser/#/R-CFA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 18009 R-CFA-2046094 https://reactome.org/PathwayBrowser/#/R-CFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Canis familiaris 18009 R-CFA-2046100 https://reactome.org/PathwayBrowser/#/R-CFA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Canis familiaris 18009 R-CFA-209921 https://reactome.org/PathwayBrowser/#/R-CFA-209921 Monoiodinated tyrosine can be deiodinated IEA Canis familiaris 18009 R-CFA-209960 https://reactome.org/PathwayBrowser/#/R-CFA-209960 Diiodinated tyrosine can be deiodinated IEA Canis familiaris 18009 R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 18009 R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 18009 R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 18009 R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 18009 R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 18009 R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 18009 R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 18009 R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 18009 R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 18009 R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 18009 R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 18009 R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 18009 R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 18009 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 18009 R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 18009 R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 18009 R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 18009 R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 18009 R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Canis familiaris 18009 R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 18009 R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 18009 R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 18009 R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 18009 R-CFA-350901 https://reactome.org/PathwayBrowser/#/R-CFA-350901 Iodide is organified IEA Canis familiaris 18009 R-CFA-389550 https://reactome.org/PathwayBrowser/#/R-CFA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 18009 R-CFA-389826 https://reactome.org/PathwayBrowser/#/R-CFA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Canis familiaris 18009 R-CFA-5623643 https://reactome.org/PathwayBrowser/#/R-CFA-5623643 RDH13 reduces atRAL to atROL IEA Canis familiaris 18009 R-CFA-5693347 https://reactome.org/PathwayBrowser/#/R-CFA-5693347 CRYM reduces P2C to PPCA IEA Canis familiaris 18009 R-CFA-5693681 https://reactome.org/PathwayBrowser/#/R-CFA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Canis familiaris 18009 R-CFA-6786720 https://reactome.org/PathwayBrowser/#/R-CFA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Canis familiaris 18009 R-CFA-6809810 https://reactome.org/PathwayBrowser/#/R-CFA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Canis familiaris 18009 R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 18009 R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 18009 R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 18009 R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 18009 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 18009 R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 18009 R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 18009 R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 18009 R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 18009 R-DDI-194674 https://reactome.org/PathwayBrowser/#/R-DDI-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Dictyostelium discoideum 18009 R-DDI-2046088 https://reactome.org/PathwayBrowser/#/R-DDI-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Dictyostelium discoideum 18009 R-DDI-2046090 https://reactome.org/PathwayBrowser/#/R-DDI-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Dictyostelium discoideum 18009 R-DDI-2046094 https://reactome.org/PathwayBrowser/#/R-DDI-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Dictyostelium discoideum 18009 R-DDI-2046100 https://reactome.org/PathwayBrowser/#/R-DDI-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Dictyostelium discoideum 18009 R-DDI-209973 https://reactome.org/PathwayBrowser/#/R-DDI-209973 Tyrosine is diiodinated IEA Dictyostelium discoideum 18009 R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 18009 R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 18009 R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 18009 R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 18009 R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 18009 R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 18009 R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 18009 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 18009 R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 18009 R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 18009 R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 18009 R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 18009 R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 18009 R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 18009 R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 18009 R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 18009 R-DDI-350901 https://reactome.org/PathwayBrowser/#/R-DDI-350901 Iodide is organified IEA Dictyostelium discoideum 18009 R-DDI-389550 https://reactome.org/PathwayBrowser/#/R-DDI-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 18009 R-DDI-5623643 https://reactome.org/PathwayBrowser/#/R-DDI-5623643 RDH13 reduces atRAL to atROL IEA Dictyostelium discoideum 18009 R-DDI-5693347 https://reactome.org/PathwayBrowser/#/R-DDI-5693347 CRYM reduces P2C to PPCA IEA Dictyostelium discoideum 18009 R-DDI-5693681 https://reactome.org/PathwayBrowser/#/R-DDI-5693681 DUOX1,2 reduce O2 to H2O2 IEA Dictyostelium discoideum 18009 R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 18009 R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 18009 R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 18009 R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 18009 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 18009 R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 18009 R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 18009 R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster 18009 R-DME-2046090 https://reactome.org/PathwayBrowser/#/R-DME-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Drosophila melanogaster 18009 R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster 18009 R-DME-2046100 https://reactome.org/PathwayBrowser/#/R-DME-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Drosophila melanogaster 18009 R-DME-209921 https://reactome.org/PathwayBrowser/#/R-DME-209921 Monoiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 18009 R-DME-209960 https://reactome.org/PathwayBrowser/#/R-DME-209960 Diiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 18009 R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 18009 R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 18009 R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 18009 R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 18009 R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 18009 R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 18009 R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 18009 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 18009 R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 18009 R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 18009 R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 18009 R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 18009 R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 18009 R-DME-350901 https://reactome.org/PathwayBrowser/#/R-DME-350901 Iodide is organified IEA Drosophila melanogaster 18009 R-DME-389550 https://reactome.org/PathwayBrowser/#/R-DME-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 18009 R-DME-389826 https://reactome.org/PathwayBrowser/#/R-DME-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Drosophila melanogaster 18009 R-DME-5693347 https://reactome.org/PathwayBrowser/#/R-DME-5693347 CRYM reduces P2C to PPCA IEA Drosophila melanogaster 18009 R-DME-5693681 https://reactome.org/PathwayBrowser/#/R-DME-5693681 DUOX1,2 reduce O2 to H2O2 IEA Drosophila melanogaster 18009 R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 18009 R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 18009 R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 18009 R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 18009 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 18009 R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 18009 R-DRE-1236967 https://reactome.org/PathwayBrowser/#/R-DRE-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Danio rerio 18009 R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 18009 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 18009 R-DRE-194674 https://reactome.org/PathwayBrowser/#/R-DRE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Danio rerio 18009 R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio 18009 R-DRE-2046090 https://reactome.org/PathwayBrowser/#/R-DRE-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 18009 R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio 18009 R-DRE-2046100 https://reactome.org/PathwayBrowser/#/R-DRE-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Danio rerio 18009 R-DRE-209921 https://reactome.org/PathwayBrowser/#/R-DRE-209921 Monoiodinated tyrosine can be deiodinated IEA Danio rerio 18009 R-DRE-209960 https://reactome.org/PathwayBrowser/#/R-DRE-209960 Diiodinated tyrosine can be deiodinated IEA Danio rerio 18009 R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 18009 R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 18009 R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 18009 R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 18009 R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 18009 R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 18009 R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 18009 R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 18009 R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 18009 R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 18009 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 18009 R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 18009 R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 18009 R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 18009 R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 18009 R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 18009 R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Danio rerio 18009 R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 18009 R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 18009 R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 18009 R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 18009 R-DRE-389550 https://reactome.org/PathwayBrowser/#/R-DRE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 18009 R-DRE-389826 https://reactome.org/PathwayBrowser/#/R-DRE-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Danio rerio 18009 R-DRE-5693347 https://reactome.org/PathwayBrowser/#/R-DRE-5693347 CRYM reduces P2C to PPCA IEA Danio rerio 18009 R-DRE-6786720 https://reactome.org/PathwayBrowser/#/R-DRE-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Danio rerio 18009 R-DRE-6809810 https://reactome.org/PathwayBrowser/#/R-DRE-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Danio rerio 18009 R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 18009 R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 18009 R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 18009 R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 18009 R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 18009 R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 18009 R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 18009 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 18009 R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 18009 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 18009 R-GGA-1236967 https://reactome.org/PathwayBrowser/#/R-GGA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Gallus gallus 18009 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 18009 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 18009 R-GGA-194674 https://reactome.org/PathwayBrowser/#/R-GGA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Gallus gallus 18009 R-GGA-2046088 https://reactome.org/PathwayBrowser/#/R-GGA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Gallus gallus 18009 R-GGA-2046090 https://reactome.org/PathwayBrowser/#/R-GGA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 18009 R-GGA-2046094 https://reactome.org/PathwayBrowser/#/R-GGA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Gallus gallus 18009 R-GGA-2046100 https://reactome.org/PathwayBrowser/#/R-GGA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Gallus gallus 18009 R-GGA-209921 https://reactome.org/PathwayBrowser/#/R-GGA-209921 Monoiodinated tyrosine can be deiodinated IEA Gallus gallus 18009 R-GGA-209960 https://reactome.org/PathwayBrowser/#/R-GGA-209960 Diiodinated tyrosine can be deiodinated IEA Gallus gallus 18009 R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 18009 R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 18009 R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 18009 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 18009 R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 18009 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 18009 R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 18009 R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 18009 R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 18009 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 18009 R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 18009 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 18009 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 18009 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 18009 R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 18009 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 18009 R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 18009 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Gallus gallus 18009 R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 18009 R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 18009 R-GGA-350901 https://reactome.org/PathwayBrowser/#/R-GGA-350901 Iodide is organified IEA Gallus gallus 18009 R-GGA-389550 https://reactome.org/PathwayBrowser/#/R-GGA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 18009 R-GGA-389826 https://reactome.org/PathwayBrowser/#/R-GGA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Gallus gallus 18009 R-GGA-5693347 https://reactome.org/PathwayBrowser/#/R-GGA-5693347 CRYM reduces P2C to PPCA IEA Gallus gallus 18009 R-GGA-5693681 https://reactome.org/PathwayBrowser/#/R-GGA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Gallus gallus 18009 R-GGA-6786720 https://reactome.org/PathwayBrowser/#/R-GGA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Gallus gallus 18009 R-GGA-6809810 https://reactome.org/PathwayBrowser/#/R-GGA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Gallus gallus 18009 R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 18009 R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 18009 R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 18009 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 18009 R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 18009 R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 18009 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 18009 R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 18009 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 18009 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 18009 R-HSA-1236967 https://reactome.org/PathwayBrowser/#/R-HSA-1236967 Alkalization of the phagosomal lumen by NOX2 TAS Homo sapiens 18009 R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 18009 R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 18009 R-HSA-194674 https://reactome.org/PathwayBrowser/#/R-HSA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] TAS Homo sapiens 18009 R-HSA-2046088 https://reactome.org/PathwayBrowser/#/R-HSA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA TAS Homo sapiens 18009 R-HSA-2046090 https://reactome.org/PathwayBrowser/#/R-HSA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 18009 R-HSA-2046094 https://reactome.org/PathwayBrowser/#/R-HSA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA TAS Homo sapiens 18009 R-HSA-2046100 https://reactome.org/PathwayBrowser/#/R-HSA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA TAS Homo sapiens 18009 R-HSA-209921 https://reactome.org/PathwayBrowser/#/R-HSA-209921 Monoiodinated tyrosine can be deiodinated TAS Homo sapiens 18009 R-HSA-209960 https://reactome.org/PathwayBrowser/#/R-HSA-209960 Diiodinated tyrosine can be deiodinated TAS Homo sapiens 18009 R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 18009 R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 18009 R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 18009 R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 18009 R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 18009 R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 18009 R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 18009 R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 18009 R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 18009 R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 18009 R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 18009 R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 18009 R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 18009 R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 18009 R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 18009 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 18009 R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 18009 R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 18009 R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 18009 R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 18009 R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 18009 R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 18009 R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 18009 R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) TAS Homo sapiens 18009 R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 18009 R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 18009 R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 18009 R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 18009 R-HSA-350901 https://reactome.org/PathwayBrowser/#/R-HSA-350901 Iodide is organified TAS Homo sapiens 18009 R-HSA-389550 https://reactome.org/PathwayBrowser/#/R-HSA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 18009 R-HSA-389826 https://reactome.org/PathwayBrowser/#/R-HSA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ TAS Homo sapiens 18009 R-HSA-5623643 https://reactome.org/PathwayBrowser/#/R-HSA-5623643 RDH13 reduces atRAL to atROL TAS Homo sapiens 18009 R-HSA-5693347 https://reactome.org/PathwayBrowser/#/R-HSA-5693347 CRYM reduces P2C to PPCA TAS Homo sapiens 18009 R-HSA-5693681 https://reactome.org/PathwayBrowser/#/R-HSA-5693681 DUOX1,2 reduce O2 to H2O2 TAS Homo sapiens 18009 R-HSA-6786720 https://reactome.org/PathwayBrowser/#/R-HSA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA TAS Homo sapiens 18009 R-HSA-6809810 https://reactome.org/PathwayBrowser/#/R-HSA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA TAS Homo sapiens 18009 R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 18009 R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 18009 R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 18009 R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 18009 R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 18009 R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 18009 R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 18009 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 18009 R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 18009 R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 18009 R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 18009 R-HSA-9661820 https://reactome.org/PathwayBrowser/#/R-HSA-9661820 Bacterial GUSB hydrolyses BDG to BIL TAS Homo sapiens 18009 R-MMU-1236967 https://reactome.org/PathwayBrowser/#/R-MMU-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Mus musculus 18009 R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 18009 R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 18009 R-MMU-194674 https://reactome.org/PathwayBrowser/#/R-MMU-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Mus musculus 18009 R-MMU-2046088 https://reactome.org/PathwayBrowser/#/R-MMU-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Mus musculus 18009 R-MMU-2046090 https://reactome.org/PathwayBrowser/#/R-MMU-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 18009 R-MMU-2046094 https://reactome.org/PathwayBrowser/#/R-MMU-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Mus musculus 18009 R-MMU-2046100 https://reactome.org/PathwayBrowser/#/R-MMU-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Mus musculus 18009 R-MMU-209921 https://reactome.org/PathwayBrowser/#/R-MMU-209921 Monoiodinated tyrosine can be deiodinated IEA Mus musculus 18009 R-MMU-209960 https://reactome.org/PathwayBrowser/#/R-MMU-209960 Diiodinated tyrosine can be deiodinated IEA Mus musculus 18009 R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 18009 R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 18009 R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 18009 R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 18009 R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 18009 R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 18009 R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 18009 R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 18009 R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 18009 R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 18009 R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 18009 R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 18009 R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 18009 R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 18009 R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 18009 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 18009 R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 18009 R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 18009 R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 18009 R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 18009 R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 18009 R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 18009 R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 18009 R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Mus musculus 18009 R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 18009 R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 18009 R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 18009 R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 18009 R-MMU-350901 https://reactome.org/PathwayBrowser/#/R-MMU-350901 Iodide is organified IEA Mus musculus 18009 R-MMU-389550 https://reactome.org/PathwayBrowser/#/R-MMU-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 18009 R-MMU-389826 https://reactome.org/PathwayBrowser/#/R-MMU-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Mus musculus 18009 R-MMU-5623643 https://reactome.org/PathwayBrowser/#/R-MMU-5623643 RDH13 reduces atRAL to atROL IEA Mus musculus 18009 R-MMU-5693347 https://reactome.org/PathwayBrowser/#/R-MMU-5693347 CRYM reduces P2C to PPCA IEA Mus musculus 18009 R-MMU-5693681 https://reactome.org/PathwayBrowser/#/R-MMU-5693681 DUOX1,2 reduce O2 to H2O2 IEA Mus musculus 18009 R-MMU-6786720 https://reactome.org/PathwayBrowser/#/R-MMU-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Mus musculus 18009 R-MMU-6809810 https://reactome.org/PathwayBrowser/#/R-MMU-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Mus musculus 18009 R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 18009 R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 18009 R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 18009 R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 18009 R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 18009 R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 18009 R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 18009 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 18009 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 18009 R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 18009 R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 18009 R-PFA-2046088 https://reactome.org/PathwayBrowser/#/R-PFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Plasmodium falciparum 18009 R-PFA-2046094 https://reactome.org/PathwayBrowser/#/R-PFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Plasmodium falciparum 18009 R-PFA-5623643 https://reactome.org/PathwayBrowser/#/R-PFA-5623643 RDH13 reduces atRAL to atROL IEA Plasmodium falciparum 18009 R-RNO-1236967 https://reactome.org/PathwayBrowser/#/R-RNO-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Rattus norvegicus 18009 R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 18009 R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 18009 R-RNO-194674 https://reactome.org/PathwayBrowser/#/R-RNO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Rattus norvegicus 18009 R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus 18009 R-RNO-2046090 https://reactome.org/PathwayBrowser/#/R-RNO-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 18009 R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus 18009 R-RNO-2046100 https://reactome.org/PathwayBrowser/#/R-RNO-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Rattus norvegicus 18009 R-RNO-209921 https://reactome.org/PathwayBrowser/#/R-RNO-209921 Monoiodinated tyrosine can be deiodinated IEA Rattus norvegicus 18009 R-RNO-209960 https://reactome.org/PathwayBrowser/#/R-RNO-209960 Diiodinated tyrosine can be deiodinated IEA Rattus norvegicus 18009 R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 18009 R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 18009 R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 18009 R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 18009 R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 18009 R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 18009 R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 18009 R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 18009 R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 18009 R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 18009 R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 18009 R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 18009 R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 18009 R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 18009 R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 18009 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 18009 R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 18009 R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 18009 R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 18009 R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 18009 R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 18009 R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 18009 R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 18009 R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Rattus norvegicus 18009 R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 18009 R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 18009 R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 18009 R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 18009 R-RNO-350901 https://reactome.org/PathwayBrowser/#/R-RNO-350901 Iodide is organified IEA Rattus norvegicus 18009 R-RNO-389550 https://reactome.org/PathwayBrowser/#/R-RNO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 18009 R-RNO-389826 https://reactome.org/PathwayBrowser/#/R-RNO-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Rattus norvegicus 18009 R-RNO-5623643 https://reactome.org/PathwayBrowser/#/R-RNO-5623643 RDH13 reduces atRAL to atROL IEA Rattus norvegicus 18009 R-RNO-5693347 https://reactome.org/PathwayBrowser/#/R-RNO-5693347 CRYM reduces P2C to PPCA IEA Rattus norvegicus 18009 R-RNO-5693681 https://reactome.org/PathwayBrowser/#/R-RNO-5693681 DUOX1,2 reduce O2 to H2O2 IEA Rattus norvegicus 18009 R-RNO-6786720 https://reactome.org/PathwayBrowser/#/R-RNO-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Rattus norvegicus 18009 R-RNO-6809810 https://reactome.org/PathwayBrowser/#/R-RNO-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Rattus norvegicus 18009 R-RNO-76354 https://reactome.org/PathwayBrowser/#/R-RNO-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Rattus norvegicus 18009 R-RNO-76373 https://reactome.org/PathwayBrowser/#/R-RNO-76373 N-hydroxylation of 4-aminobiphenyl IEA Rattus norvegicus 18009 R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 18009 R-RNO-76397 https://reactome.org/PathwayBrowser/#/R-RNO-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Rattus norvegicus 18009 R-RNO-76416 https://reactome.org/PathwayBrowser/#/R-RNO-76416 Benzene is hydroxylated to phenol IEA Rattus norvegicus 18009 R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 18009 R-RNO-76453 https://reactome.org/PathwayBrowser/#/R-RNO-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Rattus norvegicus 18009 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 18009 R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 18009 R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 18009 R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 18009 R-SCE-194674 https://reactome.org/PathwayBrowser/#/R-SCE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Saccharomyces cerevisiae 18009 R-SCE-2046088 https://reactome.org/PathwayBrowser/#/R-SCE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Saccharomyces cerevisiae 18009 R-SCE-2046094 https://reactome.org/PathwayBrowser/#/R-SCE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Saccharomyces cerevisiae 18009 R-SCE-389550 https://reactome.org/PathwayBrowser/#/R-SCE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 18009 R-SCE-5693347 https://reactome.org/PathwayBrowser/#/R-SCE-5693347 CRYM reduces P2C to PPCA IEA Saccharomyces cerevisiae 18009 R-SCE-5693681 https://reactome.org/PathwayBrowser/#/R-SCE-5693681 DUOX1,2 reduce O2 to H2O2 IEA Saccharomyces cerevisiae 18009 R-SCE-6786720 https://reactome.org/PathwayBrowser/#/R-SCE-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Saccharomyces cerevisiae 18009 R-SCE-6790127 https://reactome.org/PathwayBrowser/#/R-SCE-6790127 SMM1 (DUS2) reduces uridine-20 to dihydrouridine in tRNA(Leu) TAS Saccharomyces cerevisiae 18009 R-SPO-194674 https://reactome.org/PathwayBrowser/#/R-SPO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Schizosaccharomyces pombe 18009 R-SPO-2046088 https://reactome.org/PathwayBrowser/#/R-SPO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Schizosaccharomyces pombe 18009 R-SPO-2046094 https://reactome.org/PathwayBrowser/#/R-SPO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Schizosaccharomyces pombe 18009 R-SPO-389550 https://reactome.org/PathwayBrowser/#/R-SPO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 18009 R-SPO-5693347 https://reactome.org/PathwayBrowser/#/R-SPO-5693347 CRYM reduces P2C to PPCA IEA Schizosaccharomyces pombe 18009 R-SSC-1236967 https://reactome.org/PathwayBrowser/#/R-SSC-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Sus scrofa 18009 R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 18009 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 18009 R-SSC-194674 https://reactome.org/PathwayBrowser/#/R-SSC-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Sus scrofa 18009 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa 18009 R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 18009 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa 18009 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa 18009 R-SSC-209921 https://reactome.org/PathwayBrowser/#/R-SSC-209921 Monoiodinated tyrosine can be deiodinated IEA Sus scrofa 18009 R-SSC-209960 https://reactome.org/PathwayBrowser/#/R-SSC-209960 Diiodinated tyrosine can be deiodinated IEA Sus scrofa 18009 R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 18009 R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 18009 R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa 18009 R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 18009 R-SSC-211904 https://reactome.org/PathwayBrowser/#/R-SSC-211904 CYP4F12 18-hydroxylates ARA IEA Sus scrofa 18009 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 18009 R-SSC-211919 https://reactome.org/PathwayBrowser/#/R-SSC-211919 CYP4F8 19-hydroxylates PGH2 IEA Sus scrofa 18009 R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa 18009 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 18009 R-SSC-211948 https://reactome.org/PathwayBrowser/#/R-SSC-211948 CYP3A4 can N-demethylate loperamide IEA Sus scrofa 18009 R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 18009 R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa 18009 R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa 18009 R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa 18009 R-SSC-211968 https://reactome.org/PathwayBrowser/#/R-SSC-211968 CYP2W1 oxidises INDOL IEA Sus scrofa 18009 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 18009 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 18009 R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa 18009 R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 18009 R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa 18009 R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 18009 R-SSC-213175 https://reactome.org/PathwayBrowser/#/R-SSC-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Sus scrofa 18009 R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa 18009 R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Sus scrofa 18009 R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa 18009 R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa 18009 R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 18009 R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 18009 R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa 18009 R-SSC-389550 https://reactome.org/PathwayBrowser/#/R-SSC-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 18009 R-SSC-389826 https://reactome.org/PathwayBrowser/#/R-SSC-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Sus scrofa 18009 R-SSC-5623643 https://reactome.org/PathwayBrowser/#/R-SSC-5623643 RDH13 reduces atRAL to atROL IEA Sus scrofa 18009 R-SSC-5693347 https://reactome.org/PathwayBrowser/#/R-SSC-5693347 CRYM reduces P2C to PPCA IEA Sus scrofa 18009 R-SSC-5693681 https://reactome.org/PathwayBrowser/#/R-SSC-5693681 DUOX1,2 reduce O2 to H2O2 IEA Sus scrofa 18009 R-SSC-6786720 https://reactome.org/PathwayBrowser/#/R-SSC-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Sus scrofa 18009 R-SSC-6809810 https://reactome.org/PathwayBrowser/#/R-SSC-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Sus scrofa 18009 R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa 18009 R-SSC-76373 https://reactome.org/PathwayBrowser/#/R-SSC-76373 N-hydroxylation of 4-aminobiphenyl IEA Sus scrofa 18009 R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 18009 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa 18009 R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa 18009 R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 18009 R-SSC-76453 https://reactome.org/PathwayBrowser/#/R-SSC-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Sus scrofa 18009 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 18009 R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 18009 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 18009 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 18009 R-XTR-1236967 https://reactome.org/PathwayBrowser/#/R-XTR-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Xenopus tropicalis 18009 R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 18009 R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 18009 R-XTR-194674 https://reactome.org/PathwayBrowser/#/R-XTR-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Xenopus tropicalis 18009 R-XTR-2046088 https://reactome.org/PathwayBrowser/#/R-XTR-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Xenopus tropicalis 18009 R-XTR-2046090 https://reactome.org/PathwayBrowser/#/R-XTR-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Xenopus tropicalis 18009 R-XTR-2046094 https://reactome.org/PathwayBrowser/#/R-XTR-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Xenopus tropicalis 18009 R-XTR-2046100 https://reactome.org/PathwayBrowser/#/R-XTR-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Xenopus tropicalis 18009 R-XTR-209921 https://reactome.org/PathwayBrowser/#/R-XTR-209921 Monoiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 18009 R-XTR-209960 https://reactome.org/PathwayBrowser/#/R-XTR-209960 Diiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 18009 R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 18009 R-XTR-211881 https://reactome.org/PathwayBrowser/#/R-XTR-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Xenopus tropicalis 18009 R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 18009 R-XTR-211904 https://reactome.org/PathwayBrowser/#/R-XTR-211904 CYP4F12 18-hydroxylates ARA IEA Xenopus tropicalis 18009 R-XTR-211919 https://reactome.org/PathwayBrowser/#/R-XTR-211919 CYP4F8 19-hydroxylates PGH2 IEA Xenopus tropicalis 18009 R-XTR-211924 https://reactome.org/PathwayBrowser/#/R-XTR-211924 CYP4B1 12-hydroxylates ARA IEA Xenopus tropicalis 18009 R-XTR-211948 https://reactome.org/PathwayBrowser/#/R-XTR-211948 CYP3A4 can N-demethylate loperamide IEA Xenopus tropicalis 18009 R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 18009 R-XTR-211960 https://reactome.org/PathwayBrowser/#/R-XTR-211960 CYP2U1 19-hydroxylates ARA IEA Xenopus tropicalis 18009 R-XTR-211962 https://reactome.org/PathwayBrowser/#/R-XTR-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Xenopus tropicalis 18009 R-XTR-211966 https://reactome.org/PathwayBrowser/#/R-XTR-211966 CYP2D6 4-hydroxylates debrisoquine IEA Xenopus tropicalis 18009 R-XTR-211968 https://reactome.org/PathwayBrowser/#/R-XTR-211968 CYP2W1 oxidises INDOL IEA Xenopus tropicalis 18009 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 18009 R-XTR-211991 https://reactome.org/PathwayBrowser/#/R-XTR-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Xenopus tropicalis 18009 R-XTR-212005 https://reactome.org/PathwayBrowser/#/R-XTR-212005 CYP2F1 dehydrogenates 3-methylindole IEA Xenopus tropicalis 18009 R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 18009 R-XTR-213175 https://reactome.org/PathwayBrowser/#/R-XTR-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 18009 R-XTR-215526 https://reactome.org/PathwayBrowser/#/R-XTR-215526 CYP4F3 20-hydroxylates LTB4 IEA Xenopus tropicalis 18009 R-XTR-2161814 https://reactome.org/PathwayBrowser/#/R-XTR-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Xenopus tropicalis 18009 R-XTR-2161940 https://reactome.org/PathwayBrowser/#/R-XTR-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Xenopus tropicalis 18009 R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 18009 R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 18009 R-XTR-389550 https://reactome.org/PathwayBrowser/#/R-XTR-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 18009 R-XTR-389826 https://reactome.org/PathwayBrowser/#/R-XTR-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Xenopus tropicalis 18009 R-XTR-5623643 https://reactome.org/PathwayBrowser/#/R-XTR-5623643 RDH13 reduces atRAL to atROL IEA Xenopus tropicalis 18009 R-XTR-5693347 https://reactome.org/PathwayBrowser/#/R-XTR-5693347 CRYM reduces P2C to PPCA IEA Xenopus tropicalis 18009 R-XTR-5693681 https://reactome.org/PathwayBrowser/#/R-XTR-5693681 DUOX1,2 reduce O2 to H2O2 IEA Xenopus tropicalis 18009 R-XTR-76354 https://reactome.org/PathwayBrowser/#/R-XTR-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Xenopus tropicalis 18009 R-XTR-76397 https://reactome.org/PathwayBrowser/#/R-XTR-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Xenopus tropicalis 18009 R-XTR-76416 https://reactome.org/PathwayBrowser/#/R-XTR-76416 Benzene is hydroxylated to phenol IEA Xenopus tropicalis 18009 R-XTR-76453 https://reactome.org/PathwayBrowser/#/R-XTR-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Xenopus tropicalis 18009 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 18009 R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 18009 R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 18020 R-BTA-71249 https://reactome.org/PathwayBrowser/#/R-BTA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Bos taurus 18020 R-BTA-71260 https://reactome.org/PathwayBrowser/#/R-BTA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Bos taurus 18020 R-CEL-71249 https://reactome.org/PathwayBrowser/#/R-CEL-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Caenorhabditis elegans 18020 R-CEL-71260 https://reactome.org/PathwayBrowser/#/R-CEL-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Caenorhabditis elegans 18020 R-CFA-71249 https://reactome.org/PathwayBrowser/#/R-CFA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Canis familiaris 18020 R-CFA-71260 https://reactome.org/PathwayBrowser/#/R-CFA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Canis familiaris 18020 R-DDI-71249 https://reactome.org/PathwayBrowser/#/R-DDI-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Dictyostelium discoideum 18020 R-DME-71249 https://reactome.org/PathwayBrowser/#/R-DME-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Drosophila melanogaster 18020 R-DRE-71249 https://reactome.org/PathwayBrowser/#/R-DRE-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Danio rerio 18020 R-DRE-71260 https://reactome.org/PathwayBrowser/#/R-DRE-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Danio rerio 18020 R-GGA-71249 https://reactome.org/PathwayBrowser/#/R-GGA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Gallus gallus 18020 R-GGA-71260 https://reactome.org/PathwayBrowser/#/R-GGA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Gallus gallus 18020 R-HSA-71249 https://reactome.org/PathwayBrowser/#/R-HSA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly TAS Homo sapiens 18020 R-HSA-71260 https://reactome.org/PathwayBrowser/#/R-HSA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT TAS Homo sapiens 18020 R-MMU-71249 https://reactome.org/PathwayBrowser/#/R-MMU-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Mus musculus 18020 R-MMU-71260 https://reactome.org/PathwayBrowser/#/R-MMU-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Mus musculus 18020 R-PFA-71249 https://reactome.org/PathwayBrowser/#/R-PFA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Plasmodium falciparum 18020 R-RNO-71249 https://reactome.org/PathwayBrowser/#/R-RNO-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Rattus norvegicus 18020 R-RNO-71260 https://reactome.org/PathwayBrowser/#/R-RNO-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Rattus norvegicus 18020 R-SSC-71249 https://reactome.org/PathwayBrowser/#/R-SSC-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Sus scrofa 18020 R-SSC-71260 https://reactome.org/PathwayBrowser/#/R-SSC-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Sus scrofa 18020 R-XTR-71249 https://reactome.org/PathwayBrowser/#/R-XTR-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Xenopus tropicalis 18020 R-XTR-71260 https://reactome.org/PathwayBrowser/#/R-XTR-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Xenopus tropicalis 18022 R-BTA-8855490 https://reactome.org/PathwayBrowser/#/R-BTA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Bos taurus 18022 R-BTA-9013198 https://reactome.org/PathwayBrowser/#/R-BTA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Bos taurus 18022 R-BTA-9013471 https://reactome.org/PathwayBrowser/#/R-BTA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Bos taurus 18022 R-BTA-9013533 https://reactome.org/PathwayBrowser/#/R-BTA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Bos taurus 18022 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 18022 R-CEL-8855490 https://reactome.org/PathwayBrowser/#/R-CEL-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Caenorhabditis elegans 18022 R-CEL-9013198 https://reactome.org/PathwayBrowser/#/R-CEL-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Caenorhabditis elegans 18022 R-CEL-9013471 https://reactome.org/PathwayBrowser/#/R-CEL-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Caenorhabditis elegans 18022 R-CEL-9013533 https://reactome.org/PathwayBrowser/#/R-CEL-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Caenorhabditis elegans 18022 R-CFA-8855490 https://reactome.org/PathwayBrowser/#/R-CFA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Canis familiaris 18022 R-CFA-9013198 https://reactome.org/PathwayBrowser/#/R-CFA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Canis familiaris 18022 R-CFA-9013471 https://reactome.org/PathwayBrowser/#/R-CFA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Canis familiaris 18022 R-CFA-9013533 https://reactome.org/PathwayBrowser/#/R-CFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Canis familiaris 18022 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 18022 R-DDI-8855490 https://reactome.org/PathwayBrowser/#/R-DDI-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Dictyostelium discoideum 18022 R-DDI-9013198 https://reactome.org/PathwayBrowser/#/R-DDI-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Dictyostelium discoideum 18022 R-DDI-9013471 https://reactome.org/PathwayBrowser/#/R-DDI-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Dictyostelium discoideum 18022 R-DDI-9013533 https://reactome.org/PathwayBrowser/#/R-DDI-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Dictyostelium discoideum 18022 R-DME-8855490 https://reactome.org/PathwayBrowser/#/R-DME-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Drosophila melanogaster 18022 R-DRE-9013198 https://reactome.org/PathwayBrowser/#/R-DRE-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Danio rerio 18022 R-DRE-9013471 https://reactome.org/PathwayBrowser/#/R-DRE-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Danio rerio 18022 R-DRE-9013533 https://reactome.org/PathwayBrowser/#/R-DRE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Danio rerio 18022 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 18022 R-GGA-8855490 https://reactome.org/PathwayBrowser/#/R-GGA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Gallus gallus 18022 R-GGA-9013198 https://reactome.org/PathwayBrowser/#/R-GGA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Gallus gallus 18022 R-GGA-9013471 https://reactome.org/PathwayBrowser/#/R-GGA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Gallus gallus 18022 R-GGA-9013533 https://reactome.org/PathwayBrowser/#/R-GGA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Gallus gallus 18022 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 18022 R-HSA-8855490 https://reactome.org/PathwayBrowser/#/R-HSA-8855490 Lactoperoxidase (LPO) produces OSCN- TAS Homo sapiens 18022 R-HSA-9013198 https://reactome.org/PathwayBrowser/#/R-HSA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN TAS Homo sapiens 18022 R-HSA-9013471 https://reactome.org/PathwayBrowser/#/R-HSA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN TAS Homo sapiens 18022 R-HSA-9013533 https://reactome.org/PathwayBrowser/#/R-HSA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN TAS Homo sapiens 18022 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 18022 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 18022 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 18022 R-MMU-8855490 https://reactome.org/PathwayBrowser/#/R-MMU-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Mus musculus 18022 R-MMU-9013198 https://reactome.org/PathwayBrowser/#/R-MMU-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Mus musculus 18022 R-MMU-9013471 https://reactome.org/PathwayBrowser/#/R-MMU-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Mus musculus 18022 R-MMU-9013533 https://reactome.org/PathwayBrowser/#/R-MMU-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Mus musculus 18022 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 18022 R-PFA-9013198 https://reactome.org/PathwayBrowser/#/R-PFA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Plasmodium falciparum 18022 R-PFA-9013471 https://reactome.org/PathwayBrowser/#/R-PFA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Plasmodium falciparum 18022 R-PFA-9013533 https://reactome.org/PathwayBrowser/#/R-PFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Plasmodium falciparum 18022 R-RNO-8855490 https://reactome.org/PathwayBrowser/#/R-RNO-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Rattus norvegicus 18022 R-RNO-9013198 https://reactome.org/PathwayBrowser/#/R-RNO-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Rattus norvegicus 18022 R-RNO-9013471 https://reactome.org/PathwayBrowser/#/R-RNO-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Rattus norvegicus 18022 R-RNO-9013533 https://reactome.org/PathwayBrowser/#/R-RNO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Rattus norvegicus 18022 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 18022 R-SCE-9013198 https://reactome.org/PathwayBrowser/#/R-SCE-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Saccharomyces cerevisiae 18022 R-SCE-9013471 https://reactome.org/PathwayBrowser/#/R-SCE-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Saccharomyces cerevisiae 18022 R-SCE-9013533 https://reactome.org/PathwayBrowser/#/R-SCE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Saccharomyces cerevisiae 18022 R-SPO-9013198 https://reactome.org/PathwayBrowser/#/R-SPO-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Schizosaccharomyces pombe 18022 R-SPO-9013471 https://reactome.org/PathwayBrowser/#/R-SPO-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Schizosaccharomyces pombe 18022 R-SPO-9013533 https://reactome.org/PathwayBrowser/#/R-SPO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Schizosaccharomyces pombe 18022 R-SSC-8855490 https://reactome.org/PathwayBrowser/#/R-SSC-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Sus scrofa 18022 R-SSC-9013198 https://reactome.org/PathwayBrowser/#/R-SSC-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Sus scrofa 18022 R-SSC-9013471 https://reactome.org/PathwayBrowser/#/R-SSC-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Sus scrofa 18022 R-SSC-9013533 https://reactome.org/PathwayBrowser/#/R-SSC-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Sus scrofa 18022 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 18022 R-XTR-9013198 https://reactome.org/PathwayBrowser/#/R-XTR-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Xenopus tropicalis 18022 R-XTR-9013471 https://reactome.org/PathwayBrowser/#/R-XTR-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Xenopus tropicalis 18022 R-XTR-9013533 https://reactome.org/PathwayBrowser/#/R-XTR-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Xenopus tropicalis 18034 R-BTA-71173 https://reactome.org/PathwayBrowser/#/R-BTA-71173 GSTZ1 isomerizes 4-MAA IEA Bos taurus 18034 R-BTA-71181 https://reactome.org/PathwayBrowser/#/R-BTA-71181 FAH cleaves 4FAA IEA Bos taurus 18034 R-CEL-71173 https://reactome.org/PathwayBrowser/#/R-CEL-71173 GSTZ1 isomerizes 4-MAA IEA Caenorhabditis elegans 18034 R-CEL-71181 https://reactome.org/PathwayBrowser/#/R-CEL-71181 FAH cleaves 4FAA IEA Caenorhabditis elegans 18034 R-CFA-71173 https://reactome.org/PathwayBrowser/#/R-CFA-71173 GSTZ1 isomerizes 4-MAA IEA Canis familiaris 18034 R-CFA-71181 https://reactome.org/PathwayBrowser/#/R-CFA-71181 FAH cleaves 4FAA IEA Canis familiaris 18034 R-DDI-71173 https://reactome.org/PathwayBrowser/#/R-DDI-71173 GSTZ1 isomerizes 4-MAA IEA Dictyostelium discoideum 18034 R-DDI-71181 https://reactome.org/PathwayBrowser/#/R-DDI-71181 FAH cleaves 4FAA IEA Dictyostelium discoideum 18034 R-DME-71173 https://reactome.org/PathwayBrowser/#/R-DME-71173 GSTZ1 isomerizes 4-MAA IEA Drosophila melanogaster 18034 R-DME-71181 https://reactome.org/PathwayBrowser/#/R-DME-71181 FAH cleaves 4FAA IEA Drosophila melanogaster 18034 R-DRE-71173 https://reactome.org/PathwayBrowser/#/R-DRE-71173 GSTZ1 isomerizes 4-MAA IEA Danio rerio 18034 R-GGA-71173 https://reactome.org/PathwayBrowser/#/R-GGA-71173 GSTZ1 isomerizes 4-MAA IEA Gallus gallus 18034 R-GGA-71181 https://reactome.org/PathwayBrowser/#/R-GGA-71181 FAH cleaves 4FAA IEA Gallus gallus 18034 R-HSA-71173 https://reactome.org/PathwayBrowser/#/R-HSA-71173 GSTZ1 isomerizes 4-MAA TAS Homo sapiens 18034 R-HSA-71181 https://reactome.org/PathwayBrowser/#/R-HSA-71181 FAH cleaves 4FAA TAS Homo sapiens 18034 R-MMU-71173 https://reactome.org/PathwayBrowser/#/R-MMU-71173 GSTZ1 isomerizes 4-MAA IEA Mus musculus 18034 R-MMU-71181 https://reactome.org/PathwayBrowser/#/R-MMU-71181 FAH cleaves 4FAA IEA Mus musculus 18034 R-RNO-71173 https://reactome.org/PathwayBrowser/#/R-RNO-71173 GSTZ1 isomerizes 4-MAA IEA Rattus norvegicus 18034 R-RNO-71181 https://reactome.org/PathwayBrowser/#/R-RNO-71181 FAH cleaves 4FAA IEA Rattus norvegicus 18034 R-SSC-71173 https://reactome.org/PathwayBrowser/#/R-SSC-71173 GSTZ1 isomerizes 4-MAA IEA Sus scrofa 18034 R-SSC-71181 https://reactome.org/PathwayBrowser/#/R-SSC-71181 FAH cleaves 4FAA IEA Sus scrofa 18034 R-XTR-71173 https://reactome.org/PathwayBrowser/#/R-XTR-71173 GSTZ1 isomerizes 4-MAA IEA Xenopus tropicalis 18034 R-XTR-71181 https://reactome.org/PathwayBrowser/#/R-XTR-71181 FAH cleaves 4FAA IEA Xenopus tropicalis 18035 R-BTA-111879 https://reactome.org/PathwayBrowser/#/R-BTA-111879 PIP2 hydrolysis IEA Bos taurus 18035 R-BTA-174757 https://reactome.org/PathwayBrowser/#/R-BTA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Bos taurus 18035 R-BTA-192422 https://reactome.org/PathwayBrowser/#/R-BTA-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Bos taurus 18035 R-BTA-192430 https://reactome.org/PathwayBrowser/#/R-BTA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 18035 R-BTA-192434 https://reactome.org/PathwayBrowser/#/R-BTA-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Bos taurus 18035 R-BTA-192475 https://reactome.org/PathwayBrowser/#/R-BTA-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Bos taurus 18035 R-BTA-198314 https://reactome.org/PathwayBrowser/#/R-BTA-198314 DAG stimulates protein kinase C-delta IEA Bos taurus 18035 R-BTA-202222 https://reactome.org/PathwayBrowser/#/R-BTA-202222 Phosphorylation of PKC theta IEA Bos taurus 18035 R-BTA-202307 https://reactome.org/PathwayBrowser/#/R-BTA-202307 Change of PKC theta conformation IEA Bos taurus 18035 R-BTA-202328 https://reactome.org/PathwayBrowser/#/R-BTA-202328 Translocation of PKC theta to plasma membrane IEA Bos taurus 18035 R-BTA-202407 https://reactome.org/PathwayBrowser/#/R-BTA-202407 PLC-gamma1 hydrolyses PIP2 IEA Bos taurus 18035 R-BTA-202437 https://reactome.org/PathwayBrowser/#/R-BTA-202437 Phosphorylation of CARMA1 IEA Bos taurus 18035 R-BTA-2029468 https://reactome.org/PathwayBrowser/#/R-BTA-2029468 Conversion of PA into DAG by PAP-1 IEA Bos taurus 18035 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 18035 R-BTA-2730835 https://reactome.org/PathwayBrowser/#/R-BTA-2730835 Autophosphorylation of PKC-theta IEA Bos taurus 18035 R-BTA-2730847 https://reactome.org/PathwayBrowser/#/R-BTA-2730847 Hydrolysis of PIP2 by PLCG IEA Bos taurus 18035 R-BTA-2730861 https://reactome.org/PathwayBrowser/#/R-BTA-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 IEA Bos taurus 18035 R-BTA-2730863 https://reactome.org/PathwayBrowser/#/R-BTA-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Bos taurus 18035 R-BTA-2730864 https://reactome.org/PathwayBrowser/#/R-BTA-2730864 Recruitment of TRAF6 to CBM complex by binding to MALT1 IEA Bos taurus 18035 R-BTA-2730876 https://reactome.org/PathwayBrowser/#/R-BTA-2730876 Phosphorylation of IKK-beta by TAK1 IEA Bos taurus 18035 R-BTA-2730882 https://reactome.org/PathwayBrowser/#/R-BTA-2730882 Phosphorylation of PKC-theta IEA Bos taurus 18035 R-BTA-2730899 https://reactome.org/PathwayBrowser/#/R-BTA-2730899 Oligomerization of BCL10 and MALT1 IEA Bos taurus 18035 R-BTA-2730900 https://reactome.org/PathwayBrowser/#/R-BTA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Bos taurus 18035 R-BTA-2730902 https://reactome.org/PathwayBrowser/#/R-BTA-2730902 Oligomerization of p-CARMA1 IEA Bos taurus 18035 R-BTA-2730903 https://reactome.org/PathwayBrowser/#/R-BTA-2730903 Oligomerization of TRAF6 IEA Bos taurus 18035 R-BTA-5218813 https://reactome.org/PathwayBrowser/#/R-BTA-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Bos taurus 18035 R-BTA-5218823 https://reactome.org/PathwayBrowser/#/R-BTA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Bos taurus 18035 R-BTA-5607734 https://reactome.org/PathwayBrowser/#/R-BTA-5607734 PKC-delta translocates to plasma membrane IEA Bos taurus 18035 R-BTA-5607735 https://reactome.org/PathwayBrowser/#/R-BTA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Bos taurus 18035 R-BTA-5607740 https://reactome.org/PathwayBrowser/#/R-BTA-5607740 PKC-delta phosphorylates CARD9 IEA Bos taurus 18035 R-BTA-5607746 https://reactome.org/PathwayBrowser/#/R-BTA-5607746 PKC-delta is activated IEA Bos taurus 18035 R-BTA-5694109 https://reactome.org/PathwayBrowser/#/R-BTA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Bos taurus 18035 R-BTA-6789310 https://reactome.org/PathwayBrowser/#/R-BTA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Bos taurus 18035 R-BTA-8979996 https://reactome.org/PathwayBrowser/#/R-BTA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Bos taurus 18035 R-BTA-8980228 https://reactome.org/PathwayBrowser/#/R-BTA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Bos taurus 18035 R-BTA-9653503 https://reactome.org/PathwayBrowser/#/R-BTA-9653503 KRAS4B is phosphorylated on serine 181 IEA Bos taurus 18035 R-CEL-111879 https://reactome.org/PathwayBrowser/#/R-CEL-111879 PIP2 hydrolysis IEA Caenorhabditis elegans 18035 R-CEL-192430 https://reactome.org/PathwayBrowser/#/R-CEL-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 18035 R-CEL-198314 https://reactome.org/PathwayBrowser/#/R-CEL-198314 DAG stimulates protein kinase C-delta IEA Caenorhabditis elegans 18035 R-CEL-202222 https://reactome.org/PathwayBrowser/#/R-CEL-202222 Phosphorylation of PKC theta IEA Caenorhabditis elegans 18035 R-CEL-202328 https://reactome.org/PathwayBrowser/#/R-CEL-202328 Translocation of PKC theta to plasma membrane IEA Caenorhabditis elegans 18035 R-CEL-2730835 https://reactome.org/PathwayBrowser/#/R-CEL-2730835 Autophosphorylation of PKC-theta IEA Caenorhabditis elegans 18035 R-CEL-5218813 https://reactome.org/PathwayBrowser/#/R-CEL-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Caenorhabditis elegans 18035 R-CEL-5218823 https://reactome.org/PathwayBrowser/#/R-CEL-5218823 PKC phosphorylates sphingosine kinase 1 IEA Caenorhabditis elegans 18035 R-CEL-5607734 https://reactome.org/PathwayBrowser/#/R-CEL-5607734 PKC-delta translocates to plasma membrane IEA Caenorhabditis elegans 18035 R-CEL-5607746 https://reactome.org/PathwayBrowser/#/R-CEL-5607746 PKC-delta is activated IEA Caenorhabditis elegans 18035 R-CEL-9653503 https://reactome.org/PathwayBrowser/#/R-CEL-9653503 KRAS4B is phosphorylated on serine 181 IEA Caenorhabditis elegans 18035 R-CFA-111879 https://reactome.org/PathwayBrowser/#/R-CFA-111879 PIP2 hydrolysis IEA Canis familiaris 18035 R-CFA-174757 https://reactome.org/PathwayBrowser/#/R-CFA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Canis familiaris 18035 R-CFA-198314 https://reactome.org/PathwayBrowser/#/R-CFA-198314 DAG stimulates protein kinase C-delta IEA Canis familiaris 18035 R-CFA-202222 https://reactome.org/PathwayBrowser/#/R-CFA-202222 Phosphorylation of PKC theta IEA Canis familiaris 18035 R-CFA-202307 https://reactome.org/PathwayBrowser/#/R-CFA-202307 Change of PKC theta conformation IEA Canis familiaris 18035 R-CFA-202328 https://reactome.org/PathwayBrowser/#/R-CFA-202328 Translocation of PKC theta to plasma membrane IEA Canis familiaris 18035 R-CFA-202407 https://reactome.org/PathwayBrowser/#/R-CFA-202407 PLC-gamma1 hydrolyses PIP2 IEA Canis familiaris 18035 R-CFA-202437 https://reactome.org/PathwayBrowser/#/R-CFA-202437 Phosphorylation of CARMA1 IEA Canis familiaris 18035 R-CFA-2029468 https://reactome.org/PathwayBrowser/#/R-CFA-2029468 Conversion of PA into DAG by PAP-1 IEA Canis familiaris 18035 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 18035 R-CFA-2730835 https://reactome.org/PathwayBrowser/#/R-CFA-2730835 Autophosphorylation of PKC-theta IEA Canis familiaris 18035 R-CFA-2730847 https://reactome.org/PathwayBrowser/#/R-CFA-2730847 Hydrolysis of PIP2 by PLCG IEA Canis familiaris 18035 R-CFA-2730861 https://reactome.org/PathwayBrowser/#/R-CFA-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 IEA Canis familiaris 18035 R-CFA-2730863 https://reactome.org/PathwayBrowser/#/R-CFA-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Canis familiaris 18035 R-CFA-2730864 https://reactome.org/PathwayBrowser/#/R-CFA-2730864 Recruitment of TRAF6 to CBM complex by binding to MALT1 IEA Canis familiaris 18035 R-CFA-2730876 https://reactome.org/PathwayBrowser/#/R-CFA-2730876 Phosphorylation of IKK-beta by TAK1 IEA Canis familiaris 18035 R-CFA-2730882 https://reactome.org/PathwayBrowser/#/R-CFA-2730882 Phosphorylation of PKC-theta IEA Canis familiaris 18035 R-CFA-2730899 https://reactome.org/PathwayBrowser/#/R-CFA-2730899 Oligomerization of BCL10 and MALT1 IEA Canis familiaris 18035 R-CFA-2730900 https://reactome.org/PathwayBrowser/#/R-CFA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Canis familiaris 18035 R-CFA-2730902 https://reactome.org/PathwayBrowser/#/R-CFA-2730902 Oligomerization of p-CARMA1 IEA Canis familiaris 18035 R-CFA-2730903 https://reactome.org/PathwayBrowser/#/R-CFA-2730903 Oligomerization of TRAF6 IEA Canis familiaris 18035 R-CFA-2730904 https://reactome.org/PathwayBrowser/#/R-CFA-2730904 Auto-ubiquitination of TRAF6 IEA Canis familiaris 18035 R-CFA-5218813 https://reactome.org/PathwayBrowser/#/R-CFA-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Canis familiaris 18035 R-CFA-5218823 https://reactome.org/PathwayBrowser/#/R-CFA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Canis familiaris 18035 R-CFA-5607734 https://reactome.org/PathwayBrowser/#/R-CFA-5607734 PKC-delta translocates to plasma membrane IEA Canis familiaris 18035 R-CFA-5607735 https://reactome.org/PathwayBrowser/#/R-CFA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Canis familiaris 18035 R-CFA-5607740 https://reactome.org/PathwayBrowser/#/R-CFA-5607740 PKC-delta phosphorylates CARD9 IEA Canis familiaris 18035 R-CFA-5607746 https://reactome.org/PathwayBrowser/#/R-CFA-5607746 PKC-delta is activated IEA Canis familiaris 18035 R-CFA-5694109 https://reactome.org/PathwayBrowser/#/R-CFA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Canis familiaris 18035 R-CFA-6789310 https://reactome.org/PathwayBrowser/#/R-CFA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Canis familiaris 18035 R-CFA-8934446 https://reactome.org/PathwayBrowser/#/R-CFA-8934446 Activated PKC phosphorylates SHC1 IEA Canis familiaris 18035 R-CFA-8979996 https://reactome.org/PathwayBrowser/#/R-CFA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Canis familiaris 18035 R-CFA-8980228 https://reactome.org/PathwayBrowser/#/R-CFA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Canis familiaris 18035 R-CFA-9653503 https://reactome.org/PathwayBrowser/#/R-CFA-9653503 KRAS4B is phosphorylated on serine 181 IEA Canis familiaris 18035 R-DDI-111879 https://reactome.org/PathwayBrowser/#/R-DDI-111879 PIP2 hydrolysis IEA Dictyostelium discoideum 18035 R-DDI-198314 https://reactome.org/PathwayBrowser/#/R-DDI-198314 DAG stimulates protein kinase C-delta IEA Dictyostelium discoideum 18035 R-DDI-202222 https://reactome.org/PathwayBrowser/#/R-DDI-202222 Phosphorylation of PKC theta IEA Dictyostelium discoideum 18035 R-DDI-202328 https://reactome.org/PathwayBrowser/#/R-DDI-202328 Translocation of PKC theta to plasma membrane IEA Dictyostelium discoideum 18035 R-DDI-202407 https://reactome.org/PathwayBrowser/#/R-DDI-202407 PLC-gamma1 hydrolyses PIP2 IEA Dictyostelium discoideum 18035 R-DDI-2029468 https://reactome.org/PathwayBrowser/#/R-DDI-2029468 Conversion of PA into DAG by PAP-1 IEA Dictyostelium discoideum 18035 R-DDI-2730835 https://reactome.org/PathwayBrowser/#/R-DDI-2730835 Autophosphorylation of PKC-theta IEA Dictyostelium discoideum 18035 R-DDI-5218813 https://reactome.org/PathwayBrowser/#/R-DDI-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Dictyostelium discoideum 18035 R-DDI-5218823 https://reactome.org/PathwayBrowser/#/R-DDI-5218823 PKC phosphorylates sphingosine kinase 1 IEA Dictyostelium discoideum 18035 R-DDI-5607734 https://reactome.org/PathwayBrowser/#/R-DDI-5607734 PKC-delta translocates to plasma membrane IEA Dictyostelium discoideum 18035 R-DDI-5607735 https://reactome.org/PathwayBrowser/#/R-DDI-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Dictyostelium discoideum 18035 R-DDI-5607746 https://reactome.org/PathwayBrowser/#/R-DDI-5607746 PKC-delta is activated IEA Dictyostelium discoideum 18035 R-DDI-6789310 https://reactome.org/PathwayBrowser/#/R-DDI-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Dictyostelium discoideum 18035 R-DDI-8979996 https://reactome.org/PathwayBrowser/#/R-DDI-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Dictyostelium discoideum 18035 R-DME-111879 https://reactome.org/PathwayBrowser/#/R-DME-111879 PIP2 hydrolysis IEA Drosophila melanogaster 18035 R-DME-192430 https://reactome.org/PathwayBrowser/#/R-DME-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 18035 R-DME-192475 https://reactome.org/PathwayBrowser/#/R-DME-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Drosophila melanogaster 18035 R-DME-198314 https://reactome.org/PathwayBrowser/#/R-DME-198314 DAG stimulates protein kinase C-delta IEA Drosophila melanogaster 18035 R-DME-202222 https://reactome.org/PathwayBrowser/#/R-DME-202222 Phosphorylation of PKC theta IEA Drosophila melanogaster 18035 R-DME-202328 https://reactome.org/PathwayBrowser/#/R-DME-202328 Translocation of PKC theta to plasma membrane IEA Drosophila melanogaster 18035 R-DME-202407 https://reactome.org/PathwayBrowser/#/R-DME-202407 PLC-gamma1 hydrolyses PIP2 IEA Drosophila melanogaster 18035 R-DME-2029468 https://reactome.org/PathwayBrowser/#/R-DME-2029468 Conversion of PA into DAG by PAP-1 IEA Drosophila melanogaster 18035 R-DME-2730835 https://reactome.org/PathwayBrowser/#/R-DME-2730835 Autophosphorylation of PKC-theta IEA Drosophila melanogaster 18035 R-DME-2730847 https://reactome.org/PathwayBrowser/#/R-DME-2730847 Hydrolysis of PIP2 by PLCG IEA Drosophila melanogaster 18035 R-DME-5218813 https://reactome.org/PathwayBrowser/#/R-DME-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Drosophila melanogaster 18035 R-DME-5218823 https://reactome.org/PathwayBrowser/#/R-DME-5218823 PKC phosphorylates sphingosine kinase 1 IEA Drosophila melanogaster 18035 R-DME-5607734 https://reactome.org/PathwayBrowser/#/R-DME-5607734 PKC-delta translocates to plasma membrane IEA Drosophila melanogaster 18035 R-DME-5607735 https://reactome.org/PathwayBrowser/#/R-DME-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Drosophila melanogaster 18035 R-DME-5607746 https://reactome.org/PathwayBrowser/#/R-DME-5607746 PKC-delta is activated IEA Drosophila melanogaster 18035 R-DME-5694109 https://reactome.org/PathwayBrowser/#/R-DME-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Drosophila melanogaster 18035 R-DME-8934446 https://reactome.org/PathwayBrowser/#/R-DME-8934446 Activated PKC phosphorylates SHC1 IEA Drosophila melanogaster 18035 R-DME-8980228 https://reactome.org/PathwayBrowser/#/R-DME-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Drosophila melanogaster 18035 R-DME-9653503 https://reactome.org/PathwayBrowser/#/R-DME-9653503 KRAS4B is phosphorylated on serine 181 IEA Drosophila melanogaster 18035 R-DRE-192430 https://reactome.org/PathwayBrowser/#/R-DRE-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 18035 R-DRE-198314 https://reactome.org/PathwayBrowser/#/R-DRE-198314 DAG stimulates protein kinase C-delta IEA Danio rerio 18035 R-DRE-202407 https://reactome.org/PathwayBrowser/#/R-DRE-202407 PLC-gamma1 hydrolyses PIP2 IEA Danio rerio 18035 R-DRE-5218813 https://reactome.org/PathwayBrowser/#/R-DRE-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Danio rerio 18035 R-DRE-5607734 https://reactome.org/PathwayBrowser/#/R-DRE-5607734 PKC-delta translocates to plasma membrane IEA Danio rerio 18035 R-DRE-5607746 https://reactome.org/PathwayBrowser/#/R-DRE-5607746 PKC-delta is activated IEA Danio rerio 18035 R-DRE-5694109 https://reactome.org/PathwayBrowser/#/R-DRE-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Danio rerio 18035 R-DRE-6789310 https://reactome.org/PathwayBrowser/#/R-DRE-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Danio rerio 18035 R-DRE-8980228 https://reactome.org/PathwayBrowser/#/R-DRE-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Danio rerio 18035 R-GGA-111879 https://reactome.org/PathwayBrowser/#/R-GGA-111879 PIP2 hydrolysis IEA Gallus gallus 18035 R-GGA-192422 https://reactome.org/PathwayBrowser/#/R-GGA-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Gallus gallus 18035 R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 18035 R-GGA-192434 https://reactome.org/PathwayBrowser/#/R-GGA-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Gallus gallus 18035 R-GGA-198314 https://reactome.org/PathwayBrowser/#/R-GGA-198314 DAG stimulates protein kinase C-delta IEA Gallus gallus 18035 R-GGA-202407 https://reactome.org/PathwayBrowser/#/R-GGA-202407 PLC-gamma1 hydrolyses PIP2 IEA Gallus gallus 18035 R-GGA-2029468 https://reactome.org/PathwayBrowser/#/R-GGA-2029468 Conversion of PA into DAG by PAP-1 IEA Gallus gallus 18035 R-GGA-2730847 https://reactome.org/PathwayBrowser/#/R-GGA-2730847 Hydrolysis of PIP2 by PLCG IEA Gallus gallus 18035 R-GGA-2730861 https://reactome.org/PathwayBrowser/#/R-GGA-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 IEA Gallus gallus 18035 R-GGA-2730864 https://reactome.org/PathwayBrowser/#/R-GGA-2730864 Recruitment of TRAF6 to CBM complex by binding to MALT1 IEA Gallus gallus 18035 R-GGA-2730899 https://reactome.org/PathwayBrowser/#/R-GGA-2730899 Oligomerization of BCL10 and MALT1 IEA Gallus gallus 18035 R-GGA-2730900 https://reactome.org/PathwayBrowser/#/R-GGA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Gallus gallus 18035 R-GGA-2730903 https://reactome.org/PathwayBrowser/#/R-GGA-2730903 Oligomerization of TRAF6 IEA Gallus gallus 18035 R-GGA-5218813 https://reactome.org/PathwayBrowser/#/R-GGA-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Gallus gallus 18035 R-GGA-5218823 https://reactome.org/PathwayBrowser/#/R-GGA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Gallus gallus 18035 R-GGA-5607734 https://reactome.org/PathwayBrowser/#/R-GGA-5607734 PKC-delta translocates to plasma membrane IEA Gallus gallus 18035 R-GGA-5607735 https://reactome.org/PathwayBrowser/#/R-GGA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Gallus gallus 18035 R-GGA-5607740 https://reactome.org/PathwayBrowser/#/R-GGA-5607740 PKC-delta phosphorylates CARD9 IEA Gallus gallus 18035 R-GGA-5607746 https://reactome.org/PathwayBrowser/#/R-GGA-5607746 PKC-delta is activated IEA Gallus gallus 18035 R-GGA-5694109 https://reactome.org/PathwayBrowser/#/R-GGA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Gallus gallus 18035 R-GGA-6789310 https://reactome.org/PathwayBrowser/#/R-GGA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Gallus gallus 18035 R-GGA-8934446 https://reactome.org/PathwayBrowser/#/R-GGA-8934446 Activated PKC phosphorylates SHC1 IEA Gallus gallus 18035 R-GGA-8980228 https://reactome.org/PathwayBrowser/#/R-GGA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Gallus gallus 18035 R-HSA-111879 https://reactome.org/PathwayBrowser/#/R-HSA-111879 PIP2 hydrolysis TAS Homo sapiens 18035 R-HSA-167686 https://reactome.org/PathwayBrowser/#/R-HSA-167686 Active PLCG1 hydrolyses PIP2 IEA Homo sapiens 18035 R-HSA-174757 https://reactome.org/PathwayBrowser/#/R-HSA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols TAS Homo sapiens 18035 R-HSA-192422 https://reactome.org/PathwayBrowser/#/R-HSA-192422 Digestion of triacylglycerols by extracellular PTL:colipase TAS Homo sapiens 18035 R-HSA-192430 https://reactome.org/PathwayBrowser/#/R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 18035 R-HSA-192434 https://reactome.org/PathwayBrowser/#/R-HSA-192434 Digestion of diacylglycerols by extracellular PTL:colipase TAS Homo sapiens 18035 R-HSA-192475 https://reactome.org/PathwayBrowser/#/R-HSA-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 TAS Homo sapiens 18035 R-HSA-198314 https://reactome.org/PathwayBrowser/#/R-HSA-198314 DAG stimulates protein kinase C-delta TAS Homo sapiens 18035 R-HSA-202222 https://reactome.org/PathwayBrowser/#/R-HSA-202222 Phosphorylation of PKC theta TAS Homo sapiens 18035 R-HSA-202307 https://reactome.org/PathwayBrowser/#/R-HSA-202307 Change of PKC theta conformation TAS Homo sapiens 18035 R-HSA-202328 https://reactome.org/PathwayBrowser/#/R-HSA-202328 Translocation of PKC theta to plasma membrane TAS Homo sapiens 18035 R-HSA-202407 https://reactome.org/PathwayBrowser/#/R-HSA-202407 PLC-gamma1 hydrolyses PIP2 TAS Homo sapiens 18035 R-HSA-202437 https://reactome.org/PathwayBrowser/#/R-HSA-202437 Phosphorylation of CARMA1 TAS Homo sapiens 18035 R-HSA-2029468 https://reactome.org/PathwayBrowser/#/R-HSA-2029468 Conversion of PA into DAG by PAP-1 TAS Homo sapiens 18035 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 18035 R-HSA-2730835 https://reactome.org/PathwayBrowser/#/R-HSA-2730835 Autophosphorylation of PKC-theta TAS Homo sapiens 18035 R-HSA-2730836 https://reactome.org/PathwayBrowser/#/R-HSA-2730836 Interaction of BCL10:MALT1 with CARMA1 to form CBM complex IEA Homo sapiens 18035 R-HSA-2730847 https://reactome.org/PathwayBrowser/#/R-HSA-2730847 Hydrolysis of PIP2 by PLCG TAS Homo sapiens 18035 R-HSA-2730861 https://reactome.org/PathwayBrowser/#/R-HSA-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 TAS Homo sapiens 18035 R-HSA-2730863 https://reactome.org/PathwayBrowser/#/R-HSA-2730863 Phosphorylation of CARMA1 by PKC-theta TAS Homo sapiens 18035 R-HSA-2730864 https://reactome.org/PathwayBrowser/#/R-HSA-2730864 Recruitment of TRAF6 to CBM complex by binding to MALT1 TAS Homo sapiens 18035 R-HSA-2730871 https://reactome.org/PathwayBrowser/#/R-HSA-2730871 RasGRP interacts with DAG and Ca2+ IEA Homo sapiens 18035 R-HSA-2730876 https://reactome.org/PathwayBrowser/#/R-HSA-2730876 Phosphorylation of IKK-beta by TAK1 TAS Homo sapiens 18035 R-HSA-2730882 https://reactome.org/PathwayBrowser/#/R-HSA-2730882 Phosphorylation of PKC-theta TAS Homo sapiens 18035 R-HSA-2730899 https://reactome.org/PathwayBrowser/#/R-HSA-2730899 Oligomerization of BCL10 and MALT1 TAS Homo sapiens 18035 R-HSA-2730900 https://reactome.org/PathwayBrowser/#/R-HSA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 TAS Homo sapiens 18035 R-HSA-2730902 https://reactome.org/PathwayBrowser/#/R-HSA-2730902 Oligomerization of p-CARMA1 TAS Homo sapiens 18035 R-HSA-2730903 https://reactome.org/PathwayBrowser/#/R-HSA-2730903 Oligomerization of TRAF6 TAS Homo sapiens 18035 R-HSA-2730904 https://reactome.org/PathwayBrowser/#/R-HSA-2730904 Auto-ubiquitination of TRAF6 TAS Homo sapiens 18035 R-HSA-5218813 https://reactome.org/PathwayBrowser/#/R-HSA-5218813 DAG and Ca+2 bind to PKC and tether it to membrane TAS Homo sapiens 18035 R-HSA-5218823 https://reactome.org/PathwayBrowser/#/R-HSA-5218823 PKC phosphorylates sphingosine kinase 1 TAS Homo sapiens 18035 R-HSA-5607734 https://reactome.org/PathwayBrowser/#/R-HSA-5607734 PKC-delta translocates to plasma membrane TAS Homo sapiens 18035 R-HSA-5607735 https://reactome.org/PathwayBrowser/#/R-HSA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 TAS Homo sapiens 18035 R-HSA-5607740 https://reactome.org/PathwayBrowser/#/R-HSA-5607740 PKC-delta phosphorylates CARD9 TAS Homo sapiens 18035 R-HSA-5607746 https://reactome.org/PathwayBrowser/#/R-HSA-5607746 PKC-delta is activated TAS Homo sapiens 18035 R-HSA-5694109 https://reactome.org/PathwayBrowser/#/R-HSA-5694109 LIPC dimer hydrolyses TAG to DAG and FA TAS Homo sapiens 18035 R-HSA-622382 https://reactome.org/PathwayBrowser/#/R-HSA-622382 PIP2 hydrolysis IEA Homo sapiens 18035 R-HSA-622390 https://reactome.org/PathwayBrowser/#/R-HSA-622390 Activation of TRPC channels by Netrin-1 IEA Homo sapiens 18035 R-HSA-6789310 https://reactome.org/PathwayBrowser/#/R-HSA-6789310 LIPs hydrolyse TG to DAG and RCOOH TAS Homo sapiens 18035 R-HSA-8934446 https://reactome.org/PathwayBrowser/#/R-HSA-8934446 Activated PKC phosphorylates SHC1 TAS Homo sapiens 18035 R-HSA-8979996 https://reactome.org/PathwayBrowser/#/R-HSA-8979996 LIPs hydrolyze TG to DAG and LCFA TAS Homo sapiens 18035 R-HSA-8980228 https://reactome.org/PathwayBrowser/#/R-HSA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA TAS Homo sapiens 18035 R-HSA-9032478 https://reactome.org/PathwayBrowser/#/R-HSA-9032478 EPOR-associated PLCG hydrolyzes 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate IEA Homo sapiens 18035 R-HSA-9653503 https://reactome.org/PathwayBrowser/#/R-HSA-9653503 KRAS4B is phosphorylated on serine 181 TAS Homo sapiens 18035 R-HSA-9680388 https://reactome.org/PathwayBrowser/#/R-HSA-9680388 CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine IEA Homo sapiens 18035 R-MMU-111879 https://reactome.org/PathwayBrowser/#/R-MMU-111879 PIP2 hydrolysis IEA Mus musculus 18035 R-MMU-1169494 https://reactome.org/PathwayBrowser/#/R-MMU-1169494 Rasgrp1 and Rasgrp3 are recruited to the membrane and phosphorylated TAS Mus musculus 18035 R-MMU-174757 https://reactome.org/PathwayBrowser/#/R-MMU-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Mus musculus 18035 R-MMU-192422 https://reactome.org/PathwayBrowser/#/R-MMU-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Mus musculus 18035 R-MMU-192430 https://reactome.org/PathwayBrowser/#/R-MMU-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 18035 R-MMU-192434 https://reactome.org/PathwayBrowser/#/R-MMU-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Mus musculus 18035 R-MMU-192475 https://reactome.org/PathwayBrowser/#/R-MMU-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Mus musculus 18035 R-MMU-198314 https://reactome.org/PathwayBrowser/#/R-MMU-198314 DAG stimulates protein kinase C-delta IEA Mus musculus 18035 R-MMU-202222 https://reactome.org/PathwayBrowser/#/R-MMU-202222 Phosphorylation of PKC theta IEA Mus musculus 18035 R-MMU-202307 https://reactome.org/PathwayBrowser/#/R-MMU-202307 Change of PKC theta conformation IEA Mus musculus 18035 R-MMU-202328 https://reactome.org/PathwayBrowser/#/R-MMU-202328 Translocation of PKC theta to plasma membrane IEA Mus musculus 18035 R-MMU-202407 https://reactome.org/PathwayBrowser/#/R-MMU-202407 PLC-gamma1 hydrolyses PIP2 IEA Mus musculus 18035 R-MMU-202437 https://reactome.org/PathwayBrowser/#/R-MMU-202437 Phosphorylation of CARMA1 IEA Mus musculus 18035 R-MMU-2029468 https://reactome.org/PathwayBrowser/#/R-MMU-2029468 Conversion of PA into DAG by PAP-1 IEA Mus musculus 18035 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 18035 R-MMU-2730835 https://reactome.org/PathwayBrowser/#/R-MMU-2730835 Autophosphorylation of PKC-theta IEA Mus musculus 18035 R-MMU-2730847 https://reactome.org/PathwayBrowser/#/R-MMU-2730847 Hydrolysis of PIP2 by PLCG IEA Mus musculus 18035 R-MMU-2730861 https://reactome.org/PathwayBrowser/#/R-MMU-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 IEA Mus musculus 18035 R-MMU-2730863 https://reactome.org/PathwayBrowser/#/R-MMU-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Mus musculus 18035 R-MMU-2730864 https://reactome.org/PathwayBrowser/#/R-MMU-2730864 Recruitment of TRAF6 to CBM complex by binding to MALT1 IEA Mus musculus 18035 R-MMU-2730865 https://reactome.org/PathwayBrowser/#/R-MMU-2730865 RasGRP interacts with DAG and Ca2+ TAS Mus musculus 18035 R-MMU-2730876 https://reactome.org/PathwayBrowser/#/R-MMU-2730876 Phosphorylation of IKK-beta by TAK1 IEA Mus musculus 18035 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus 18035 R-MMU-2730899 https://reactome.org/PathwayBrowser/#/R-MMU-2730899 Oligomerization of BCL10 and MALT1 IEA Mus musculus 18035 R-MMU-2730900 https://reactome.org/PathwayBrowser/#/R-MMU-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Mus musculus 18035 R-MMU-2730902 https://reactome.org/PathwayBrowser/#/R-MMU-2730902 Oligomerization of p-CARMA1 IEA Mus musculus 18035 R-MMU-2730903 https://reactome.org/PathwayBrowser/#/R-MMU-2730903 Oligomerization of TRAF6 IEA Mus musculus 18035 R-MMU-2730904 https://reactome.org/PathwayBrowser/#/R-MMU-2730904 Auto-ubiquitination of TRAF6 IEA Mus musculus 18035 R-MMU-5218813 https://reactome.org/PathwayBrowser/#/R-MMU-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Mus musculus 18035 R-MMU-5218823 https://reactome.org/PathwayBrowser/#/R-MMU-5218823 PKC phosphorylates sphingosine kinase 1 IEA Mus musculus 18035 R-MMU-5607734 https://reactome.org/PathwayBrowser/#/R-MMU-5607734 PKC-delta translocates to plasma membrane IEA Mus musculus 18035 R-MMU-5607735 https://reactome.org/PathwayBrowser/#/R-MMU-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Mus musculus 18035 R-MMU-5607740 https://reactome.org/PathwayBrowser/#/R-MMU-5607740 PKC-delta phosphorylates CARD9 IEA Mus musculus 18035 R-MMU-5607746 https://reactome.org/PathwayBrowser/#/R-MMU-5607746 PKC-delta is activated IEA Mus musculus 18035 R-MMU-5694109 https://reactome.org/PathwayBrowser/#/R-MMU-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Mus musculus 18035 R-MMU-6789310 https://reactome.org/PathwayBrowser/#/R-MMU-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Mus musculus 18035 R-MMU-8934446 https://reactome.org/PathwayBrowser/#/R-MMU-8934446 Activated PKC phosphorylates SHC1 IEA Mus musculus 18035 R-MMU-8979996 https://reactome.org/PathwayBrowser/#/R-MMU-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Mus musculus 18035 R-MMU-8980228 https://reactome.org/PathwayBrowser/#/R-MMU-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Mus musculus 18035 R-MMU-9032476 https://reactome.org/PathwayBrowser/#/R-MMU-9032476 Epor-associated Plcg hydrolyzes 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate TAS Mus musculus 18035 R-MMU-9653503 https://reactome.org/PathwayBrowser/#/R-MMU-9653503 KRAS4B is phosphorylated on serine 181 IEA Mus musculus 18035 R-PFA-202407 https://reactome.org/PathwayBrowser/#/R-PFA-202407 PLC-gamma1 hydrolyses PIP2 IEA Plasmodium falciparum 18035 R-PFA-5607735 https://reactome.org/PathwayBrowser/#/R-PFA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Plasmodium falciparum 18035 R-PFA-6789310 https://reactome.org/PathwayBrowser/#/R-PFA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Plasmodium falciparum 18035 R-PFA-8979996 https://reactome.org/PathwayBrowser/#/R-PFA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Plasmodium falciparum 18035 R-RNO-111879 https://reactome.org/PathwayBrowser/#/R-RNO-111879 PIP2 hydrolysis IEA Rattus norvegicus 18035 R-RNO-174757 https://reactome.org/PathwayBrowser/#/R-RNO-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Rattus norvegicus 18035 R-RNO-182061 https://reactome.org/PathwayBrowser/#/R-RNO-182061 Active Plcg1 hydrolyses PIP2 TAS Rattus norvegicus 18035 R-RNO-192422 https://reactome.org/PathwayBrowser/#/R-RNO-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Rattus norvegicus 18035 R-RNO-192430 https://reactome.org/PathwayBrowser/#/R-RNO-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 18035 R-RNO-192434 https://reactome.org/PathwayBrowser/#/R-RNO-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Rattus norvegicus 18035 R-RNO-192475 https://reactome.org/PathwayBrowser/#/R-RNO-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Rattus norvegicus 18035 R-RNO-198314 https://reactome.org/PathwayBrowser/#/R-RNO-198314 DAG stimulates protein kinase C-delta IEA Rattus norvegicus 18035 R-RNO-202222 https://reactome.org/PathwayBrowser/#/R-RNO-202222 Phosphorylation of PKC theta IEA Rattus norvegicus 18035 R-RNO-202307 https://reactome.org/PathwayBrowser/#/R-RNO-202307 Change of PKC theta conformation IEA Rattus norvegicus 18035 R-RNO-202328 https://reactome.org/PathwayBrowser/#/R-RNO-202328 Translocation of PKC theta to plasma membrane IEA Rattus norvegicus 18035 R-RNO-202407 https://reactome.org/PathwayBrowser/#/R-RNO-202407 PLC-gamma1 hydrolyses PIP2 IEA Rattus norvegicus 18035 R-RNO-202437 https://reactome.org/PathwayBrowser/#/R-RNO-202437 Phosphorylation of CARMA1 IEA Rattus norvegicus 18035 R-RNO-2029468 https://reactome.org/PathwayBrowser/#/R-RNO-2029468 Conversion of PA into DAG by PAP-1 IEA Rattus norvegicus 18035 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 18035 R-RNO-2730835 https://reactome.org/PathwayBrowser/#/R-RNO-2730835 Autophosphorylation of PKC-theta IEA Rattus norvegicus 18035 R-RNO-2730847 https://reactome.org/PathwayBrowser/#/R-RNO-2730847 Hydrolysis of PIP2 by PLCG IEA Rattus norvegicus 18035 R-RNO-2730861 https://reactome.org/PathwayBrowser/#/R-RNO-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 IEA Rattus norvegicus 18035 R-RNO-2730863 https://reactome.org/PathwayBrowser/#/R-RNO-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Rattus norvegicus 18035 R-RNO-2730864 https://reactome.org/PathwayBrowser/#/R-RNO-2730864 Recruitment of TRAF6 to CBM complex by binding to MALT1 IEA Rattus norvegicus 18035 R-RNO-2730876 https://reactome.org/PathwayBrowser/#/R-RNO-2730876 Phosphorylation of IKK-beta by TAK1 IEA Rattus norvegicus 18035 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus 18035 R-RNO-2730899 https://reactome.org/PathwayBrowser/#/R-RNO-2730899 Oligomerization of BCL10 and MALT1 IEA Rattus norvegicus 18035 R-RNO-2730900 https://reactome.org/PathwayBrowser/#/R-RNO-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Rattus norvegicus 18035 R-RNO-2730902 https://reactome.org/PathwayBrowser/#/R-RNO-2730902 Oligomerization of p-CARMA1 IEA Rattus norvegicus 18035 R-RNO-2730903 https://reactome.org/PathwayBrowser/#/R-RNO-2730903 Oligomerization of TRAF6 IEA Rattus norvegicus 18035 R-RNO-5218813 https://reactome.org/PathwayBrowser/#/R-RNO-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Rattus norvegicus 18035 R-RNO-5218823 https://reactome.org/PathwayBrowser/#/R-RNO-5218823 PKC phosphorylates sphingosine kinase 1 IEA Rattus norvegicus 18035 R-RNO-5607734 https://reactome.org/PathwayBrowser/#/R-RNO-5607734 PKC-delta translocates to plasma membrane IEA Rattus norvegicus 18035 R-RNO-5607735 https://reactome.org/PathwayBrowser/#/R-RNO-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Rattus norvegicus 18035 R-RNO-5607740 https://reactome.org/PathwayBrowser/#/R-RNO-5607740 PKC-delta phosphorylates CARD9 IEA Rattus norvegicus 18035 R-RNO-5607746 https://reactome.org/PathwayBrowser/#/R-RNO-5607746 PKC-delta is activated IEA Rattus norvegicus 18035 R-RNO-5694109 https://reactome.org/PathwayBrowser/#/R-RNO-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Rattus norvegicus 18035 R-RNO-622387 https://reactome.org/PathwayBrowser/#/R-RNO-622387 PIP2 hydrolysis TAS Rattus norvegicus 18035 R-RNO-6789310 https://reactome.org/PathwayBrowser/#/R-RNO-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Rattus norvegicus 18035 R-RNO-8934446 https://reactome.org/PathwayBrowser/#/R-RNO-8934446 Activated PKC phosphorylates SHC1 IEA Rattus norvegicus 18035 R-RNO-8979996 https://reactome.org/PathwayBrowser/#/R-RNO-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Rattus norvegicus 18035 R-RNO-8980228 https://reactome.org/PathwayBrowser/#/R-RNO-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Rattus norvegicus 18035 R-RNO-9653503 https://reactome.org/PathwayBrowser/#/R-RNO-9653503 KRAS4B is phosphorylated on serine 181 IEA Rattus norvegicus 18035 R-SCE-111879 https://reactome.org/PathwayBrowser/#/R-SCE-111879 PIP2 hydrolysis IEA Saccharomyces cerevisiae 18035 R-SCE-198314 https://reactome.org/PathwayBrowser/#/R-SCE-198314 DAG stimulates protein kinase C-delta IEA Saccharomyces cerevisiae 18035 R-SCE-202222 https://reactome.org/PathwayBrowser/#/R-SCE-202222 Phosphorylation of PKC theta IEA Saccharomyces cerevisiae 18035 R-SCE-202328 https://reactome.org/PathwayBrowser/#/R-SCE-202328 Translocation of PKC theta to plasma membrane IEA Saccharomyces cerevisiae 18035 R-SCE-202407 https://reactome.org/PathwayBrowser/#/R-SCE-202407 PLC-gamma1 hydrolyses PIP2 IEA Saccharomyces cerevisiae 18035 R-SCE-2029468 https://reactome.org/PathwayBrowser/#/R-SCE-2029468 Conversion of PA into DAG by PAP-1 IEA Saccharomyces cerevisiae 18035 R-SCE-2730835 https://reactome.org/PathwayBrowser/#/R-SCE-2730835 Autophosphorylation of PKC-theta IEA Saccharomyces cerevisiae 18035 R-SCE-5218813 https://reactome.org/PathwayBrowser/#/R-SCE-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Saccharomyces cerevisiae 18035 R-SCE-5218823 https://reactome.org/PathwayBrowser/#/R-SCE-5218823 PKC phosphorylates sphingosine kinase 1 IEA Saccharomyces cerevisiae 18035 R-SCE-5607734 https://reactome.org/PathwayBrowser/#/R-SCE-5607734 PKC-delta translocates to plasma membrane IEA Saccharomyces cerevisiae 18035 R-SCE-5607735 https://reactome.org/PathwayBrowser/#/R-SCE-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Saccharomyces cerevisiae 18035 R-SCE-5607746 https://reactome.org/PathwayBrowser/#/R-SCE-5607746 PKC-delta is activated IEA Saccharomyces cerevisiae 18035 R-SCE-6789310 https://reactome.org/PathwayBrowser/#/R-SCE-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Saccharomyces cerevisiae 18035 R-SCE-8979996 https://reactome.org/PathwayBrowser/#/R-SCE-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Saccharomyces cerevisiae 18035 R-SPO-111879 https://reactome.org/PathwayBrowser/#/R-SPO-111879 PIP2 hydrolysis IEA Schizosaccharomyces pombe 18035 R-SPO-198314 https://reactome.org/PathwayBrowser/#/R-SPO-198314 DAG stimulates protein kinase C-delta IEA Schizosaccharomyces pombe 18035 R-SPO-202222 https://reactome.org/PathwayBrowser/#/R-SPO-202222 Phosphorylation of PKC theta IEA Schizosaccharomyces pombe 18035 R-SPO-202328 https://reactome.org/PathwayBrowser/#/R-SPO-202328 Translocation of PKC theta to plasma membrane IEA Schizosaccharomyces pombe 18035 R-SPO-202407 https://reactome.org/PathwayBrowser/#/R-SPO-202407 PLC-gamma1 hydrolyses PIP2 IEA Schizosaccharomyces pombe 18035 R-SPO-2029468 https://reactome.org/PathwayBrowser/#/R-SPO-2029468 Conversion of PA into DAG by PAP-1 IEA Schizosaccharomyces pombe 18035 R-SPO-2730835 https://reactome.org/PathwayBrowser/#/R-SPO-2730835 Autophosphorylation of PKC-theta IEA Schizosaccharomyces pombe 18035 R-SPO-5218813 https://reactome.org/PathwayBrowser/#/R-SPO-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Schizosaccharomyces pombe 18035 R-SPO-5218823 https://reactome.org/PathwayBrowser/#/R-SPO-5218823 PKC phosphorylates sphingosine kinase 1 IEA Schizosaccharomyces pombe 18035 R-SPO-5607734 https://reactome.org/PathwayBrowser/#/R-SPO-5607734 PKC-delta translocates to plasma membrane IEA Schizosaccharomyces pombe 18035 R-SPO-5607735 https://reactome.org/PathwayBrowser/#/R-SPO-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Schizosaccharomyces pombe 18035 R-SPO-5607746 https://reactome.org/PathwayBrowser/#/R-SPO-5607746 PKC-delta is activated IEA Schizosaccharomyces pombe 18035 R-SPO-6789310 https://reactome.org/PathwayBrowser/#/R-SPO-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Schizosaccharomyces pombe 18035 R-SPO-8979996 https://reactome.org/PathwayBrowser/#/R-SPO-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Schizosaccharomyces pombe 18035 R-SSC-111879 https://reactome.org/PathwayBrowser/#/R-SSC-111879 PIP2 hydrolysis IEA Sus scrofa 18035 R-SSC-174757 https://reactome.org/PathwayBrowser/#/R-SSC-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Sus scrofa 18035 R-SSC-192422 https://reactome.org/PathwayBrowser/#/R-SSC-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Sus scrofa 18035 R-SSC-192430 https://reactome.org/PathwayBrowser/#/R-SSC-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 18035 R-SSC-192434 https://reactome.org/PathwayBrowser/#/R-SSC-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Sus scrofa 18035 R-SSC-192475 https://reactome.org/PathwayBrowser/#/R-SSC-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Sus scrofa 18035 R-SSC-198314 https://reactome.org/PathwayBrowser/#/R-SSC-198314 DAG stimulates protein kinase C-delta IEA Sus scrofa 18035 R-SSC-202222 https://reactome.org/PathwayBrowser/#/R-SSC-202222 Phosphorylation of PKC theta IEA Sus scrofa 18035 R-SSC-202307 https://reactome.org/PathwayBrowser/#/R-SSC-202307 Change of PKC theta conformation IEA Sus scrofa 18035 R-SSC-202328 https://reactome.org/PathwayBrowser/#/R-SSC-202328 Translocation of PKC theta to plasma membrane IEA Sus scrofa 18035 R-SSC-202407 https://reactome.org/PathwayBrowser/#/R-SSC-202407 PLC-gamma1 hydrolyses PIP2 IEA Sus scrofa 18035 R-SSC-202437 https://reactome.org/PathwayBrowser/#/R-SSC-202437 Phosphorylation of CARMA1 IEA Sus scrofa 18035 R-SSC-2029468 https://reactome.org/PathwayBrowser/#/R-SSC-2029468 Conversion of PA into DAG by PAP-1 IEA Sus scrofa 18035 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 18035 R-SSC-2730835 https://reactome.org/PathwayBrowser/#/R-SSC-2730835 Autophosphorylation of PKC-theta IEA Sus scrofa 18035 R-SSC-2730847 https://reactome.org/PathwayBrowser/#/R-SSC-2730847 Hydrolysis of PIP2 by PLCG IEA Sus scrofa 18035 R-SSC-2730861 https://reactome.org/PathwayBrowser/#/R-SSC-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 IEA Sus scrofa 18035 R-SSC-2730863 https://reactome.org/PathwayBrowser/#/R-SSC-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Sus scrofa 18035 R-SSC-2730864 https://reactome.org/PathwayBrowser/#/R-SSC-2730864 Recruitment of TRAF6 to CBM complex by binding to MALT1 IEA Sus scrofa 18035 R-SSC-2730876 https://reactome.org/PathwayBrowser/#/R-SSC-2730876 Phosphorylation of IKK-beta by TAK1 IEA Sus scrofa 18035 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa 18035 R-SSC-2730899 https://reactome.org/PathwayBrowser/#/R-SSC-2730899 Oligomerization of BCL10 and MALT1 IEA Sus scrofa 18035 R-SSC-2730900 https://reactome.org/PathwayBrowser/#/R-SSC-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Sus scrofa 18035 R-SSC-2730902 https://reactome.org/PathwayBrowser/#/R-SSC-2730902 Oligomerization of p-CARMA1 IEA Sus scrofa 18035 R-SSC-2730903 https://reactome.org/PathwayBrowser/#/R-SSC-2730903 Oligomerization of TRAF6 IEA Sus scrofa 18035 R-SSC-2730904 https://reactome.org/PathwayBrowser/#/R-SSC-2730904 Auto-ubiquitination of TRAF6 IEA Sus scrofa 18035 R-SSC-5218813 https://reactome.org/PathwayBrowser/#/R-SSC-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Sus scrofa 18035 R-SSC-5218823 https://reactome.org/PathwayBrowser/#/R-SSC-5218823 PKC phosphorylates sphingosine kinase 1 IEA Sus scrofa 18035 R-SSC-5607734 https://reactome.org/PathwayBrowser/#/R-SSC-5607734 PKC-delta translocates to plasma membrane IEA Sus scrofa 18035 R-SSC-5607735 https://reactome.org/PathwayBrowser/#/R-SSC-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Sus scrofa 18035 R-SSC-5607740 https://reactome.org/PathwayBrowser/#/R-SSC-5607740 PKC-delta phosphorylates CARD9 IEA Sus scrofa 18035 R-SSC-5607746 https://reactome.org/PathwayBrowser/#/R-SSC-5607746 PKC-delta is activated IEA Sus scrofa 18035 R-SSC-5694109 https://reactome.org/PathwayBrowser/#/R-SSC-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Sus scrofa 18035 R-SSC-6789310 https://reactome.org/PathwayBrowser/#/R-SSC-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Sus scrofa 18035 R-SSC-8934446 https://reactome.org/PathwayBrowser/#/R-SSC-8934446 Activated PKC phosphorylates SHC1 IEA Sus scrofa 18035 R-SSC-8980228 https://reactome.org/PathwayBrowser/#/R-SSC-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Sus scrofa 18035 R-SSC-9653503 https://reactome.org/PathwayBrowser/#/R-SSC-9653503 KRAS4B is phosphorylated on serine 181 IEA Sus scrofa 18035 R-XLA-622403 https://reactome.org/PathwayBrowser/#/R-XLA-622403 Activation of TRPC channels by Netrin-1 TAS Xenopus laevis 18035 R-XTR-111879 https://reactome.org/PathwayBrowser/#/R-XTR-111879 PIP2 hydrolysis IEA Xenopus tropicalis 18035 R-XTR-192422 https://reactome.org/PathwayBrowser/#/R-XTR-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis 18035 R-XTR-192430 https://reactome.org/PathwayBrowser/#/R-XTR-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 18035 R-XTR-192434 https://reactome.org/PathwayBrowser/#/R-XTR-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis 18035 R-XTR-198314 https://reactome.org/PathwayBrowser/#/R-XTR-198314 DAG stimulates protein kinase C-delta IEA Xenopus tropicalis 18035 R-XTR-202407 https://reactome.org/PathwayBrowser/#/R-XTR-202407 PLC-gamma1 hydrolyses PIP2 IEA Xenopus tropicalis 18035 R-XTR-2029468 https://reactome.org/PathwayBrowser/#/R-XTR-2029468 Conversion of PA into DAG by PAP-1 IEA Xenopus tropicalis 18035 R-XTR-2730847 https://reactome.org/PathwayBrowser/#/R-XTR-2730847 Hydrolysis of PIP2 by PLCG IEA Xenopus tropicalis 18035 R-XTR-5218813 https://reactome.org/PathwayBrowser/#/R-XTR-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Xenopus tropicalis 18035 R-XTR-5607734 https://reactome.org/PathwayBrowser/#/R-XTR-5607734 PKC-delta translocates to plasma membrane IEA Xenopus tropicalis 18035 R-XTR-5607735 https://reactome.org/PathwayBrowser/#/R-XTR-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Xenopus tropicalis 18035 R-XTR-5607740 https://reactome.org/PathwayBrowser/#/R-XTR-5607740 PKC-delta phosphorylates CARD9 IEA Xenopus tropicalis 18035 R-XTR-5607746 https://reactome.org/PathwayBrowser/#/R-XTR-5607746 PKC-delta is activated IEA Xenopus tropicalis 18035 R-XTR-5694109 https://reactome.org/PathwayBrowser/#/R-XTR-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Xenopus tropicalis 18035 R-XTR-8980228 https://reactome.org/PathwayBrowser/#/R-XTR-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Xenopus tropicalis 18036 R-BTA-8866601 https://reactome.org/PathwayBrowser/#/R-BTA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Bos taurus 18036 R-CEL-8866601 https://reactome.org/PathwayBrowser/#/R-CEL-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Caenorhabditis elegans 18036 R-CFA-8866601 https://reactome.org/PathwayBrowser/#/R-CFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Canis familiaris 18036 R-DDI-8866601 https://reactome.org/PathwayBrowser/#/R-DDI-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Dictyostelium discoideum 18036 R-DME-8866601 https://reactome.org/PathwayBrowser/#/R-DME-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Drosophila melanogaster 18036 R-DRE-8866601 https://reactome.org/PathwayBrowser/#/R-DRE-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Danio rerio 18036 R-GGA-8866601 https://reactome.org/PathwayBrowser/#/R-GGA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Gallus gallus 18036 R-HSA-8866601 https://reactome.org/PathwayBrowser/#/R-HSA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate TAS Homo sapiens 18036 R-MMU-8866601 https://reactome.org/PathwayBrowser/#/R-MMU-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Mus musculus 18036 R-PFA-8866601 https://reactome.org/PathwayBrowser/#/R-PFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Plasmodium falciparum 18036 R-RNO-8866601 https://reactome.org/PathwayBrowser/#/R-RNO-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Rattus norvegicus 18036 R-SSC-8866601 https://reactome.org/PathwayBrowser/#/R-SSC-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Sus scrofa 18036 R-XTR-8866601 https://reactome.org/PathwayBrowser/#/R-XTR-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Xenopus tropicalis 180460 R-BTA-9753632 https://reactome.org/PathwayBrowser/#/R-BTA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Bos taurus 180460 R-BTA-9753634 https://reactome.org/PathwayBrowser/#/R-BTA-9753634 GGT dimers hydrolyse APAP-SG IEA Bos taurus 180460 R-CEL-9753632 https://reactome.org/PathwayBrowser/#/R-CEL-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Caenorhabditis elegans 180460 R-CEL-9753634 https://reactome.org/PathwayBrowser/#/R-CEL-9753634 GGT dimers hydrolyse APAP-SG IEA Caenorhabditis elegans 180460 R-CFA-9753632 https://reactome.org/PathwayBrowser/#/R-CFA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Canis familiaris 180460 R-CFA-9753634 https://reactome.org/PathwayBrowser/#/R-CFA-9753634 GGT dimers hydrolyse APAP-SG IEA Canis familiaris 180460 R-DDI-9753632 https://reactome.org/PathwayBrowser/#/R-DDI-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Dictyostelium discoideum 180460 R-DME-9753632 https://reactome.org/PathwayBrowser/#/R-DME-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Drosophila melanogaster 180460 R-DME-9753634 https://reactome.org/PathwayBrowser/#/R-DME-9753634 GGT dimers hydrolyse APAP-SG IEA Drosophila melanogaster 180460 R-DRE-9753632 https://reactome.org/PathwayBrowser/#/R-DRE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Danio rerio 180460 R-GGA-9753632 https://reactome.org/PathwayBrowser/#/R-GGA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Gallus gallus 180460 R-GGA-9753634 https://reactome.org/PathwayBrowser/#/R-GGA-9753634 GGT dimers hydrolyse APAP-SG IEA Gallus gallus 180460 R-HSA-9753632 https://reactome.org/PathwayBrowser/#/R-HSA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly TAS Homo sapiens 180460 R-HSA-9753634 https://reactome.org/PathwayBrowser/#/R-HSA-9753634 GGT dimers hydrolyse APAP-SG TAS Homo sapiens 180460 R-MMU-9753632 https://reactome.org/PathwayBrowser/#/R-MMU-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Mus musculus 180460 R-MMU-9753634 https://reactome.org/PathwayBrowser/#/R-MMU-9753634 GGT dimers hydrolyse APAP-SG IEA Mus musculus 180460 R-RNO-9753632 https://reactome.org/PathwayBrowser/#/R-RNO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Rattus norvegicus 180460 R-RNO-9753634 https://reactome.org/PathwayBrowser/#/R-RNO-9753634 GGT dimers hydrolyse APAP-SG IEA Rattus norvegicus 180460 R-SCE-9753632 https://reactome.org/PathwayBrowser/#/R-SCE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Saccharomyces cerevisiae 180460 R-SCE-9753634 https://reactome.org/PathwayBrowser/#/R-SCE-9753634 GGT dimers hydrolyse APAP-SG IEA Saccharomyces cerevisiae 180460 R-SPO-9753632 https://reactome.org/PathwayBrowser/#/R-SPO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Schizosaccharomyces pombe 180460 R-SPO-9753634 https://reactome.org/PathwayBrowser/#/R-SPO-9753634 GGT dimers hydrolyse APAP-SG IEA Schizosaccharomyces pombe 180460 R-SSC-9753632 https://reactome.org/PathwayBrowser/#/R-SSC-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Sus scrofa 180460 R-SSC-9753634 https://reactome.org/PathwayBrowser/#/R-SSC-9753634 GGT dimers hydrolyse APAP-SG IEA Sus scrofa 180460 R-XTR-9753632 https://reactome.org/PathwayBrowser/#/R-XTR-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Xenopus tropicalis 180482 R-BTA-9755044 https://reactome.org/PathwayBrowser/#/R-BTA-9755044 PNP trimer transforms RBV to T-CONH2 IEA Bos taurus 180482 R-CEL-9755044 https://reactome.org/PathwayBrowser/#/R-CEL-9755044 PNP trimer transforms RBV to T-CONH2 IEA Caenorhabditis elegans 180482 R-CFA-9755044 https://reactome.org/PathwayBrowser/#/R-CFA-9755044 PNP trimer transforms RBV to T-CONH2 IEA Canis familiaris 180482 R-DME-9755044 https://reactome.org/PathwayBrowser/#/R-DME-9755044 PNP trimer transforms RBV to T-CONH2 IEA Drosophila melanogaster 180482 R-DRE-9755044 https://reactome.org/PathwayBrowser/#/R-DRE-9755044 PNP trimer transforms RBV to T-CONH2 IEA Danio rerio 180482 R-HSA-9755044 https://reactome.org/PathwayBrowser/#/R-HSA-9755044 PNP trimer transforms RBV to T-CONH2 TAS Homo sapiens 180482 R-MMU-9755044 https://reactome.org/PathwayBrowser/#/R-MMU-9755044 PNP trimer transforms RBV to T-CONH2 IEA Mus musculus 180482 R-RNO-9755044 https://reactome.org/PathwayBrowser/#/R-RNO-9755044 PNP trimer transforms RBV to T-CONH2 IEA Rattus norvegicus 180482 R-SCE-9755044 https://reactome.org/PathwayBrowser/#/R-SCE-9755044 PNP trimer transforms RBV to T-CONH2 IEA Saccharomyces cerevisiae 180482 R-SPO-9755044 https://reactome.org/PathwayBrowser/#/R-SPO-9755044 PNP trimer transforms RBV to T-CONH2 IEA Schizosaccharomyces pombe 180482 R-SSC-9755044 https://reactome.org/PathwayBrowser/#/R-SSC-9755044 PNP trimer transforms RBV to T-CONH2 IEA Sus scrofa 180482 R-XTR-9755044 https://reactome.org/PathwayBrowser/#/R-XTR-9755044 PNP trimer transforms RBV to T-CONH2 IEA Xenopus tropicalis 18059 R-BTA-5229283 https://reactome.org/PathwayBrowser/#/R-BTA-5229283 LCNs bind lipids IEA Bos taurus 18059 R-BTA-5682285 https://reactome.org/PathwayBrowser/#/R-BTA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Bos taurus 18059 R-CEL-5682285 https://reactome.org/PathwayBrowser/#/R-CEL-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Caenorhabditis elegans 18059 R-CFA-5229283 https://reactome.org/PathwayBrowser/#/R-CFA-5229283 LCNs bind lipids IEA Canis familiaris 18059 R-CFA-5682285 https://reactome.org/PathwayBrowser/#/R-CFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Canis familiaris 18059 R-DDI-5682285 https://reactome.org/PathwayBrowser/#/R-DDI-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Dictyostelium discoideum 18059 R-DME-5229283 https://reactome.org/PathwayBrowser/#/R-DME-5229283 LCNs bind lipids IEA Drosophila melanogaster 18059 R-DME-5682285 https://reactome.org/PathwayBrowser/#/R-DME-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Drosophila melanogaster 18059 R-DRE-5229283 https://reactome.org/PathwayBrowser/#/R-DRE-5229283 LCNs bind lipids IEA Danio rerio 18059 R-GGA-5229283 https://reactome.org/PathwayBrowser/#/R-GGA-5229283 LCNs bind lipids IEA Gallus gallus 18059 R-GGA-5682285 https://reactome.org/PathwayBrowser/#/R-GGA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Gallus gallus 18059 R-HSA-5229283 https://reactome.org/PathwayBrowser/#/R-HSA-5229283 LCNs bind lipids TAS Homo sapiens 18059 R-HSA-5682285 https://reactome.org/PathwayBrowser/#/R-HSA-5682285 ABCA12 transports lipids from cytosol to extracellular region TAS Homo sapiens 18059 R-HSA-5682311 https://reactome.org/PathwayBrowser/#/R-HSA-5682311 Defective ABCA12 does not transport lipids from cytosol to extracellular region TAS Homo sapiens 18059 R-HSA-6789042 https://reactome.org/PathwayBrowser/#/R-HSA-6789042 Hydroxyl-initiated lipid peroxidation TAS Homo sapiens 18059 R-HSA-6789218 https://reactome.org/PathwayBrowser/#/R-HSA-6789218 Hypochlorous acid (HOCl) reacts with unsaturated lipid to form lipid chlorohydrins TAS Homo sapiens 18059 R-MMU-5229283 https://reactome.org/PathwayBrowser/#/R-MMU-5229283 LCNs bind lipids IEA Mus musculus 18059 R-MMU-5682285 https://reactome.org/PathwayBrowser/#/R-MMU-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Mus musculus 18059 R-PFA-5682285 https://reactome.org/PathwayBrowser/#/R-PFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Plasmodium falciparum 18059 R-RNO-5229283 https://reactome.org/PathwayBrowser/#/R-RNO-5229283 LCNs bind lipids IEA Rattus norvegicus 18059 R-RNO-5682285 https://reactome.org/PathwayBrowser/#/R-RNO-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Rattus norvegicus 18059 R-SSC-5229283 https://reactome.org/PathwayBrowser/#/R-SSC-5229283 LCNs bind lipids IEA Sus scrofa 18059 R-SSC-5682285 https://reactome.org/PathwayBrowser/#/R-SSC-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Sus scrofa 18059 R-XTR-5229283 https://reactome.org/PathwayBrowser/#/R-XTR-5229283 LCNs bind lipids IEA Xenopus tropicalis 180684 R-BTA-9748945 https://reactome.org/PathwayBrowser/#/R-BTA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Bos taurus 180684 R-BTA-9748951 https://reactome.org/PathwayBrowser/#/R-BTA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Bos taurus 180684 R-BTA-9748979 https://reactome.org/PathwayBrowser/#/R-BTA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Bos taurus 180684 R-BTA-9750546 https://reactome.org/PathwayBrowser/#/R-BTA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 180684 R-BTA-9750617 https://reactome.org/PathwayBrowser/#/R-BTA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 180684 R-CEL-9748945 https://reactome.org/PathwayBrowser/#/R-CEL-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Caenorhabditis elegans 180684 R-CEL-9748951 https://reactome.org/PathwayBrowser/#/R-CEL-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Caenorhabditis elegans 180684 R-CEL-9750546 https://reactome.org/PathwayBrowser/#/R-CEL-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 180684 R-CEL-9750617 https://reactome.org/PathwayBrowser/#/R-CEL-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 180684 R-CFA-9748945 https://reactome.org/PathwayBrowser/#/R-CFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Canis familiaris 180684 R-CFA-9748951 https://reactome.org/PathwayBrowser/#/R-CFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Canis familiaris 180684 R-CFA-9748979 https://reactome.org/PathwayBrowser/#/R-CFA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Canis familiaris 180684 R-CFA-9750546 https://reactome.org/PathwayBrowser/#/R-CFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 180684 R-CFA-9750617 https://reactome.org/PathwayBrowser/#/R-CFA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 180684 R-DDI-9748945 https://reactome.org/PathwayBrowser/#/R-DDI-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Dictyostelium discoideum 180684 R-DDI-9748951 https://reactome.org/PathwayBrowser/#/R-DDI-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Dictyostelium discoideum 180684 R-DDI-9750546 https://reactome.org/PathwayBrowser/#/R-DDI-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Dictyostelium discoideum 180684 R-DME-9748945 https://reactome.org/PathwayBrowser/#/R-DME-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Drosophila melanogaster 180684 R-DME-9750546 https://reactome.org/PathwayBrowser/#/R-DME-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Drosophila melanogaster 180684 R-DRE-9748945 https://reactome.org/PathwayBrowser/#/R-DRE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Danio rerio 180684 R-DRE-9748951 https://reactome.org/PathwayBrowser/#/R-DRE-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Danio rerio 180684 R-DRE-9748979 https://reactome.org/PathwayBrowser/#/R-DRE-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Danio rerio 180684 R-DRE-9750546 https://reactome.org/PathwayBrowser/#/R-DRE-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 180684 R-DRE-9750617 https://reactome.org/PathwayBrowser/#/R-DRE-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 180684 R-GGA-9748945 https://reactome.org/PathwayBrowser/#/R-GGA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Gallus gallus 180684 R-GGA-9748951 https://reactome.org/PathwayBrowser/#/R-GGA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Gallus gallus 180684 R-GGA-9748979 https://reactome.org/PathwayBrowser/#/R-GGA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Gallus gallus 180684 R-GGA-9750546 https://reactome.org/PathwayBrowser/#/R-GGA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 180684 R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 180684 R-HSA-9748945 https://reactome.org/PathwayBrowser/#/R-HSA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP TAS Homo sapiens 180684 R-HSA-9748951 https://reactome.org/PathwayBrowser/#/R-HSA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP TAS Homo sapiens 180684 R-HSA-9748979 https://reactome.org/PathwayBrowser/#/R-HSA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP TAS Homo sapiens 180684 R-HSA-9750546 https://reactome.org/PathwayBrowser/#/R-HSA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 180684 R-HSA-9750617 https://reactome.org/PathwayBrowser/#/R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 180684 R-MMU-9748945 https://reactome.org/PathwayBrowser/#/R-MMU-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Mus musculus 180684 R-MMU-9748951 https://reactome.org/PathwayBrowser/#/R-MMU-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Mus musculus 180684 R-MMU-9748979 https://reactome.org/PathwayBrowser/#/R-MMU-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Mus musculus 180684 R-MMU-9750546 https://reactome.org/PathwayBrowser/#/R-MMU-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 180684 R-MMU-9750617 https://reactome.org/PathwayBrowser/#/R-MMU-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 180684 R-PFA-9748945 https://reactome.org/PathwayBrowser/#/R-PFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Plasmodium falciparum 180684 R-PFA-9748951 https://reactome.org/PathwayBrowser/#/R-PFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Plasmodium falciparum 180684 R-PFA-9750546 https://reactome.org/PathwayBrowser/#/R-PFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Plasmodium falciparum 180684 R-RNO-9748945 https://reactome.org/PathwayBrowser/#/R-RNO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Rattus norvegicus 180684 R-RNO-9748951 https://reactome.org/PathwayBrowser/#/R-RNO-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Rattus norvegicus 180684 R-RNO-9748979 https://reactome.org/PathwayBrowser/#/R-RNO-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Rattus norvegicus 180684 R-RNO-9750546 https://reactome.org/PathwayBrowser/#/R-RNO-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 180684 R-RNO-9750617 https://reactome.org/PathwayBrowser/#/R-RNO-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 180684 R-SCE-9748945 https://reactome.org/PathwayBrowser/#/R-SCE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Saccharomyces cerevisiae 180684 R-SPO-9748945 https://reactome.org/PathwayBrowser/#/R-SPO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Schizosaccharomyces pombe 180684 R-SSC-9748945 https://reactome.org/PathwayBrowser/#/R-SSC-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Sus scrofa 180684 R-SSC-9748951 https://reactome.org/PathwayBrowser/#/R-SSC-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Sus scrofa 180684 R-SSC-9748979 https://reactome.org/PathwayBrowser/#/R-SSC-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Sus scrofa 180684 R-SSC-9750546 https://reactome.org/PathwayBrowser/#/R-SSC-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 180684 R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 180684 R-XTR-9748945 https://reactome.org/PathwayBrowser/#/R-XTR-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Xenopus tropicalis 180684 R-XTR-9748979 https://reactome.org/PathwayBrowser/#/R-XTR-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Xenopus tropicalis 180684 R-XTR-9750617 https://reactome.org/PathwayBrowser/#/R-XTR-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Xenopus tropicalis 180685 R-BTA-9748945 https://reactome.org/PathwayBrowser/#/R-BTA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Bos taurus 180685 R-BTA-9748957 https://reactome.org/PathwayBrowser/#/R-BTA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Bos taurus 180685 R-BTA-9750617 https://reactome.org/PathwayBrowser/#/R-BTA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 180685 R-CEL-9748945 https://reactome.org/PathwayBrowser/#/R-CEL-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Caenorhabditis elegans 180685 R-CEL-9748957 https://reactome.org/PathwayBrowser/#/R-CEL-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Caenorhabditis elegans 180685 R-CEL-9750617 https://reactome.org/PathwayBrowser/#/R-CEL-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 180685 R-CFA-9748945 https://reactome.org/PathwayBrowser/#/R-CFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Canis familiaris 180685 R-CFA-9748957 https://reactome.org/PathwayBrowser/#/R-CFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Canis familiaris 180685 R-CFA-9750617 https://reactome.org/PathwayBrowser/#/R-CFA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 180685 R-DDI-9748945 https://reactome.org/PathwayBrowser/#/R-DDI-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Dictyostelium discoideum 180685 R-DDI-9748957 https://reactome.org/PathwayBrowser/#/R-DDI-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Dictyostelium discoideum 180685 R-DME-9748945 https://reactome.org/PathwayBrowser/#/R-DME-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Drosophila melanogaster 180685 R-DME-9748957 https://reactome.org/PathwayBrowser/#/R-DME-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Drosophila melanogaster 180685 R-DRE-9748945 https://reactome.org/PathwayBrowser/#/R-DRE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Danio rerio 180685 R-DRE-9750617 https://reactome.org/PathwayBrowser/#/R-DRE-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 180685 R-GGA-9748945 https://reactome.org/PathwayBrowser/#/R-GGA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Gallus gallus 180685 R-GGA-9748957 https://reactome.org/PathwayBrowser/#/R-GGA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Gallus gallus 180685 R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 180685 R-HSA-9748945 https://reactome.org/PathwayBrowser/#/R-HSA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP TAS Homo sapiens 180685 R-HSA-9748957 https://reactome.org/PathwayBrowser/#/R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP TAS Homo sapiens 180685 R-HSA-9750617 https://reactome.org/PathwayBrowser/#/R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 180685 R-MMU-9748945 https://reactome.org/PathwayBrowser/#/R-MMU-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Mus musculus 180685 R-MMU-9748957 https://reactome.org/PathwayBrowser/#/R-MMU-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Mus musculus 180685 R-MMU-9750617 https://reactome.org/PathwayBrowser/#/R-MMU-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 180685 R-PFA-9748945 https://reactome.org/PathwayBrowser/#/R-PFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Plasmodium falciparum 180685 R-PFA-9748957 https://reactome.org/PathwayBrowser/#/R-PFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Plasmodium falciparum 180685 R-RNO-9748945 https://reactome.org/PathwayBrowser/#/R-RNO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Rattus norvegicus 180685 R-RNO-9748957 https://reactome.org/PathwayBrowser/#/R-RNO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Rattus norvegicus 180685 R-RNO-9750617 https://reactome.org/PathwayBrowser/#/R-RNO-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 180685 R-SCE-9748945 https://reactome.org/PathwayBrowser/#/R-SCE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Saccharomyces cerevisiae 180685 R-SCE-9748957 https://reactome.org/PathwayBrowser/#/R-SCE-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Saccharomyces cerevisiae 180685 R-SPO-9748945 https://reactome.org/PathwayBrowser/#/R-SPO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Schizosaccharomyces pombe 180685 R-SPO-9748957 https://reactome.org/PathwayBrowser/#/R-SPO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Schizosaccharomyces pombe 180685 R-SSC-9748945 https://reactome.org/PathwayBrowser/#/R-SSC-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Sus scrofa 180685 R-SSC-9748957 https://reactome.org/PathwayBrowser/#/R-SSC-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Sus scrofa 180685 R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 180685 R-XTR-9748945 https://reactome.org/PathwayBrowser/#/R-XTR-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Xenopus tropicalis 180685 R-XTR-9748957 https://reactome.org/PathwayBrowser/#/R-XTR-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Xenopus tropicalis 180685 R-XTR-9750617 https://reactome.org/PathwayBrowser/#/R-XTR-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Xenopus tropicalis 180686 R-BTA-9748949 https://reactome.org/PathwayBrowser/#/R-BTA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Bos taurus 180686 R-BTA-9748957 https://reactome.org/PathwayBrowser/#/R-BTA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Bos taurus 180686 R-BTA-9750546 https://reactome.org/PathwayBrowser/#/R-BTA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 180686 R-BTA-9750617 https://reactome.org/PathwayBrowser/#/R-BTA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 180686 R-CEL-9748949 https://reactome.org/PathwayBrowser/#/R-CEL-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Caenorhabditis elegans 180686 R-CEL-9748957 https://reactome.org/PathwayBrowser/#/R-CEL-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Caenorhabditis elegans 180686 R-CEL-9750546 https://reactome.org/PathwayBrowser/#/R-CEL-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 180686 R-CEL-9750617 https://reactome.org/PathwayBrowser/#/R-CEL-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 180686 R-CFA-9748949 https://reactome.org/PathwayBrowser/#/R-CFA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Canis familiaris 180686 R-CFA-9748957 https://reactome.org/PathwayBrowser/#/R-CFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Canis familiaris 180686 R-CFA-9750546 https://reactome.org/PathwayBrowser/#/R-CFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 180686 R-CFA-9750617 https://reactome.org/PathwayBrowser/#/R-CFA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 180686 R-DDI-9748949 https://reactome.org/PathwayBrowser/#/R-DDI-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Dictyostelium discoideum 180686 R-DDI-9748957 https://reactome.org/PathwayBrowser/#/R-DDI-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Dictyostelium discoideum 180686 R-DDI-9750546 https://reactome.org/PathwayBrowser/#/R-DDI-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Dictyostelium discoideum 180686 R-DME-9748949 https://reactome.org/PathwayBrowser/#/R-DME-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Drosophila melanogaster 180686 R-DME-9748957 https://reactome.org/PathwayBrowser/#/R-DME-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Drosophila melanogaster 180686 R-DME-9750546 https://reactome.org/PathwayBrowser/#/R-DME-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Drosophila melanogaster 180686 R-DRE-9748949 https://reactome.org/PathwayBrowser/#/R-DRE-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Danio rerio 180686 R-DRE-9750546 https://reactome.org/PathwayBrowser/#/R-DRE-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 180686 R-DRE-9750617 https://reactome.org/PathwayBrowser/#/R-DRE-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 180686 R-GGA-9748949 https://reactome.org/PathwayBrowser/#/R-GGA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Gallus gallus 180686 R-GGA-9748957 https://reactome.org/PathwayBrowser/#/R-GGA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Gallus gallus 180686 R-GGA-9750546 https://reactome.org/PathwayBrowser/#/R-GGA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 180686 R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 180686 R-HSA-9748949 https://reactome.org/PathwayBrowser/#/R-HSA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP TAS Homo sapiens 180686 R-HSA-9748957 https://reactome.org/PathwayBrowser/#/R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP TAS Homo sapiens 180686 R-HSA-9750546 https://reactome.org/PathwayBrowser/#/R-HSA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 180686 R-HSA-9750617 https://reactome.org/PathwayBrowser/#/R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 180686 R-MMU-9748949 https://reactome.org/PathwayBrowser/#/R-MMU-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Mus musculus 180686 R-MMU-9748957 https://reactome.org/PathwayBrowser/#/R-MMU-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Mus musculus 180686 R-MMU-9750546 https://reactome.org/PathwayBrowser/#/R-MMU-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 180686 R-MMU-9750617 https://reactome.org/PathwayBrowser/#/R-MMU-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 180686 R-PFA-9748949 https://reactome.org/PathwayBrowser/#/R-PFA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Plasmodium falciparum 180686 R-PFA-9748957 https://reactome.org/PathwayBrowser/#/R-PFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Plasmodium falciparum 180686 R-PFA-9750546 https://reactome.org/PathwayBrowser/#/R-PFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Plasmodium falciparum 180686 R-RNO-9748949 https://reactome.org/PathwayBrowser/#/R-RNO-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Rattus norvegicus 180686 R-RNO-9748957 https://reactome.org/PathwayBrowser/#/R-RNO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Rattus norvegicus 180686 R-RNO-9750546 https://reactome.org/PathwayBrowser/#/R-RNO-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 180686 R-RNO-9750617 https://reactome.org/PathwayBrowser/#/R-RNO-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 180686 R-SCE-9748949 https://reactome.org/PathwayBrowser/#/R-SCE-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Saccharomyces cerevisiae 180686 R-SCE-9748957 https://reactome.org/PathwayBrowser/#/R-SCE-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Saccharomyces cerevisiae 180686 R-SPO-9748949 https://reactome.org/PathwayBrowser/#/R-SPO-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Schizosaccharomyces pombe 180686 R-SPO-9748957 https://reactome.org/PathwayBrowser/#/R-SPO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Schizosaccharomyces pombe 180686 R-SSC-9748949 https://reactome.org/PathwayBrowser/#/R-SSC-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Sus scrofa 180686 R-SSC-9748957 https://reactome.org/PathwayBrowser/#/R-SSC-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Sus scrofa 180686 R-SSC-9750546 https://reactome.org/PathwayBrowser/#/R-SSC-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 180686 R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 180686 R-XTR-9748949 https://reactome.org/PathwayBrowser/#/R-XTR-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Xenopus tropicalis 180686 R-XTR-9748957 https://reactome.org/PathwayBrowser/#/R-XTR-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Xenopus tropicalis 180686 R-XTR-9750617 https://reactome.org/PathwayBrowser/#/R-XTR-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Xenopus tropicalis 180687 R-BTA-9748949 https://reactome.org/PathwayBrowser/#/R-BTA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Bos taurus 180687 R-BTA-9748999 https://reactome.org/PathwayBrowser/#/R-BTA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Bos taurus 180687 R-CEL-9748949 https://reactome.org/PathwayBrowser/#/R-CEL-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Caenorhabditis elegans 180687 R-CEL-9748999 https://reactome.org/PathwayBrowser/#/R-CEL-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Caenorhabditis elegans 180687 R-CFA-9748949 https://reactome.org/PathwayBrowser/#/R-CFA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Canis familiaris 180687 R-CFA-9748999 https://reactome.org/PathwayBrowser/#/R-CFA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Canis familiaris 180687 R-DDI-9748949 https://reactome.org/PathwayBrowser/#/R-DDI-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Dictyostelium discoideum 180687 R-DDI-9748999 https://reactome.org/PathwayBrowser/#/R-DDI-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Dictyostelium discoideum 180687 R-DME-9748949 https://reactome.org/PathwayBrowser/#/R-DME-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Drosophila melanogaster 180687 R-DME-9748999 https://reactome.org/PathwayBrowser/#/R-DME-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Drosophila melanogaster 180687 R-DRE-9748949 https://reactome.org/PathwayBrowser/#/R-DRE-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Danio rerio 180687 R-DRE-9748999 https://reactome.org/PathwayBrowser/#/R-DRE-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Danio rerio 180687 R-GGA-9748949 https://reactome.org/PathwayBrowser/#/R-GGA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Gallus gallus 180687 R-GGA-9748999 https://reactome.org/PathwayBrowser/#/R-GGA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Gallus gallus 180687 R-HSA-9748949 https://reactome.org/PathwayBrowser/#/R-HSA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP TAS Homo sapiens 180687 R-HSA-9748999 https://reactome.org/PathwayBrowser/#/R-HSA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP TAS Homo sapiens 180687 R-MMU-9748949 https://reactome.org/PathwayBrowser/#/R-MMU-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Mus musculus 180687 R-MMU-9748999 https://reactome.org/PathwayBrowser/#/R-MMU-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Mus musculus 180687 R-PFA-9748949 https://reactome.org/PathwayBrowser/#/R-PFA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Plasmodium falciparum 180687 R-PFA-9748999 https://reactome.org/PathwayBrowser/#/R-PFA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Plasmodium falciparum 180687 R-RNO-9748949 https://reactome.org/PathwayBrowser/#/R-RNO-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Rattus norvegicus 180687 R-RNO-9748999 https://reactome.org/PathwayBrowser/#/R-RNO-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Rattus norvegicus 180687 R-SCE-9748949 https://reactome.org/PathwayBrowser/#/R-SCE-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Saccharomyces cerevisiae 180687 R-SCE-9748999 https://reactome.org/PathwayBrowser/#/R-SCE-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Saccharomyces cerevisiae 180687 R-SPO-9748949 https://reactome.org/PathwayBrowser/#/R-SPO-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Schizosaccharomyces pombe 180687 R-SPO-9748999 https://reactome.org/PathwayBrowser/#/R-SPO-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Schizosaccharomyces pombe 180687 R-SSC-9748949 https://reactome.org/PathwayBrowser/#/R-SSC-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Sus scrofa 180687 R-SSC-9748999 https://reactome.org/PathwayBrowser/#/R-SSC-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Sus scrofa 180687 R-XTR-9748949 https://reactome.org/PathwayBrowser/#/R-XTR-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Xenopus tropicalis 180688 R-BTA-9748999 https://reactome.org/PathwayBrowser/#/R-BTA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Bos taurus 180688 R-BTA-9751201 https://reactome.org/PathwayBrowser/#/R-BTA-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Bos taurus 180688 R-CEL-9748999 https://reactome.org/PathwayBrowser/#/R-CEL-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Caenorhabditis elegans 180688 R-CEL-9751201 https://reactome.org/PathwayBrowser/#/R-CEL-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Caenorhabditis elegans 180688 R-CFA-9748999 https://reactome.org/PathwayBrowser/#/R-CFA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Canis familiaris 180688 R-CFA-9751201 https://reactome.org/PathwayBrowser/#/R-CFA-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Canis familiaris 180688 R-DDI-9748999 https://reactome.org/PathwayBrowser/#/R-DDI-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Dictyostelium discoideum 180688 R-DME-9748999 https://reactome.org/PathwayBrowser/#/R-DME-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Drosophila melanogaster 180688 R-DME-9751201 https://reactome.org/PathwayBrowser/#/R-DME-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Drosophila melanogaster 180688 R-DRE-9748999 https://reactome.org/PathwayBrowser/#/R-DRE-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Danio rerio 180688 R-GGA-9748999 https://reactome.org/PathwayBrowser/#/R-GGA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Gallus gallus 180688 R-GGA-9751201 https://reactome.org/PathwayBrowser/#/R-GGA-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Gallus gallus 180688 R-HSA-9748999 https://reactome.org/PathwayBrowser/#/R-HSA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP TAS Homo sapiens 180688 R-HSA-9751201 https://reactome.org/PathwayBrowser/#/R-HSA-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 TAS Homo sapiens 180688 R-MMU-9748999 https://reactome.org/PathwayBrowser/#/R-MMU-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Mus musculus 180688 R-MMU-9751201 https://reactome.org/PathwayBrowser/#/R-MMU-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Mus musculus 180688 R-PFA-9748999 https://reactome.org/PathwayBrowser/#/R-PFA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Plasmodium falciparum 180688 R-RNO-9748999 https://reactome.org/PathwayBrowser/#/R-RNO-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Rattus norvegicus 180688 R-RNO-9751201 https://reactome.org/PathwayBrowser/#/R-RNO-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Rattus norvegicus 180688 R-SCE-9748999 https://reactome.org/PathwayBrowser/#/R-SCE-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Saccharomyces cerevisiae 180688 R-SPO-9748999 https://reactome.org/PathwayBrowser/#/R-SPO-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Schizosaccharomyces pombe 180688 R-SSC-9748999 https://reactome.org/PathwayBrowser/#/R-SSC-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Sus scrofa 180688 R-SSC-9751201 https://reactome.org/PathwayBrowser/#/R-SSC-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Sus scrofa 180688 R-XTR-9751201 https://reactome.org/PathwayBrowser/#/R-XTR-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Xenopus tropicalis 180689 R-BTA-9748963 https://reactome.org/PathwayBrowser/#/R-BTA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Bos taurus 180689 R-BTA-9750555 https://reactome.org/PathwayBrowser/#/R-BTA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Bos taurus 180689 R-CEL-9748963 https://reactome.org/PathwayBrowser/#/R-CEL-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Caenorhabditis elegans 180689 R-CFA-9748963 https://reactome.org/PathwayBrowser/#/R-CFA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Canis familiaris 180689 R-CFA-9750555 https://reactome.org/PathwayBrowser/#/R-CFA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Canis familiaris 180689 R-DDI-9748963 https://reactome.org/PathwayBrowser/#/R-DDI-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Dictyostelium discoideum 180689 R-DME-9748963 https://reactome.org/PathwayBrowser/#/R-DME-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Drosophila melanogaster 180689 R-DRE-9748963 https://reactome.org/PathwayBrowser/#/R-DRE-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Danio rerio 180689 R-GGA-9748963 https://reactome.org/PathwayBrowser/#/R-GGA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Gallus gallus 180689 R-GGA-9750555 https://reactome.org/PathwayBrowser/#/R-GGA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Gallus gallus 180689 R-HSA-9748963 https://reactome.org/PathwayBrowser/#/R-HSA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP TAS Homo sapiens 180689 R-HSA-9750555 https://reactome.org/PathwayBrowser/#/R-HSA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP TAS Homo sapiens 180689 R-MMU-9748963 https://reactome.org/PathwayBrowser/#/R-MMU-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Mus musculus 180689 R-MMU-9750555 https://reactome.org/PathwayBrowser/#/R-MMU-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Mus musculus 180689 R-PFA-9748963 https://reactome.org/PathwayBrowser/#/R-PFA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Plasmodium falciparum 180689 R-RNO-9748963 https://reactome.org/PathwayBrowser/#/R-RNO-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Rattus norvegicus 180689 R-RNO-9750555 https://reactome.org/PathwayBrowser/#/R-RNO-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Rattus norvegicus 180689 R-SCE-9748963 https://reactome.org/PathwayBrowser/#/R-SCE-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Saccharomyces cerevisiae 180689 R-SPO-9748963 https://reactome.org/PathwayBrowser/#/R-SPO-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Schizosaccharomyces pombe 180689 R-SSC-9748963 https://reactome.org/PathwayBrowser/#/R-SSC-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Sus scrofa 180689 R-SSC-9750555 https://reactome.org/PathwayBrowser/#/R-SSC-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Sus scrofa 180689 R-XTR-9748963 https://reactome.org/PathwayBrowser/#/R-XTR-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Xenopus tropicalis 180689 R-XTR-9750555 https://reactome.org/PathwayBrowser/#/R-XTR-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Xenopus tropicalis 180690 R-BTA-9748963 https://reactome.org/PathwayBrowser/#/R-BTA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Bos taurus 180690 R-BTA-9748969 https://reactome.org/PathwayBrowser/#/R-BTA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Bos taurus 180690 R-CEL-9748963 https://reactome.org/PathwayBrowser/#/R-CEL-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Caenorhabditis elegans 180690 R-CEL-9748969 https://reactome.org/PathwayBrowser/#/R-CEL-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Caenorhabditis elegans 180690 R-CFA-9748963 https://reactome.org/PathwayBrowser/#/R-CFA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Canis familiaris 180690 R-CFA-9748969 https://reactome.org/PathwayBrowser/#/R-CFA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Canis familiaris 180690 R-DDI-9748963 https://reactome.org/PathwayBrowser/#/R-DDI-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Dictyostelium discoideum 180690 R-DDI-9748969 https://reactome.org/PathwayBrowser/#/R-DDI-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Dictyostelium discoideum 180690 R-DME-9748963 https://reactome.org/PathwayBrowser/#/R-DME-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Drosophila melanogaster 180690 R-DME-9748969 https://reactome.org/PathwayBrowser/#/R-DME-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Drosophila melanogaster 180690 R-DRE-9748963 https://reactome.org/PathwayBrowser/#/R-DRE-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Danio rerio 180690 R-DRE-9748969 https://reactome.org/PathwayBrowser/#/R-DRE-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Danio rerio 180690 R-GGA-9748963 https://reactome.org/PathwayBrowser/#/R-GGA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Gallus gallus 180690 R-GGA-9748969 https://reactome.org/PathwayBrowser/#/R-GGA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Gallus gallus 180690 R-HSA-9748963 https://reactome.org/PathwayBrowser/#/R-HSA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP TAS Homo sapiens 180690 R-HSA-9748969 https://reactome.org/PathwayBrowser/#/R-HSA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP TAS Homo sapiens 180690 R-MMU-9748963 https://reactome.org/PathwayBrowser/#/R-MMU-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Mus musculus 180690 R-MMU-9748969 https://reactome.org/PathwayBrowser/#/R-MMU-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Mus musculus 180690 R-PFA-9748963 https://reactome.org/PathwayBrowser/#/R-PFA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Plasmodium falciparum 180690 R-PFA-9748969 https://reactome.org/PathwayBrowser/#/R-PFA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Plasmodium falciparum 180690 R-RNO-9748963 https://reactome.org/PathwayBrowser/#/R-RNO-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Rattus norvegicus 180690 R-RNO-9748969 https://reactome.org/PathwayBrowser/#/R-RNO-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Rattus norvegicus 180690 R-SCE-9748963 https://reactome.org/PathwayBrowser/#/R-SCE-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Saccharomyces cerevisiae 180690 R-SCE-9748969 https://reactome.org/PathwayBrowser/#/R-SCE-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Saccharomyces cerevisiae 180690 R-SPO-9748963 https://reactome.org/PathwayBrowser/#/R-SPO-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Schizosaccharomyces pombe 180690 R-SPO-9748969 https://reactome.org/PathwayBrowser/#/R-SPO-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Schizosaccharomyces pombe 180690 R-SSC-9748963 https://reactome.org/PathwayBrowser/#/R-SSC-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Sus scrofa 180690 R-SSC-9748969 https://reactome.org/PathwayBrowser/#/R-SSC-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Sus scrofa 180690 R-XTR-9748963 https://reactome.org/PathwayBrowser/#/R-XTR-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Xenopus tropicalis 180691 R-BTA-9748969 https://reactome.org/PathwayBrowser/#/R-BTA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Bos taurus 180691 R-BTA-9750555 https://reactome.org/PathwayBrowser/#/R-BTA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Bos taurus 180691 R-CEL-9748969 https://reactome.org/PathwayBrowser/#/R-CEL-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Caenorhabditis elegans 180691 R-CFA-9748969 https://reactome.org/PathwayBrowser/#/R-CFA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Canis familiaris 180691 R-CFA-9750555 https://reactome.org/PathwayBrowser/#/R-CFA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Canis familiaris 180691 R-DDI-9748969 https://reactome.org/PathwayBrowser/#/R-DDI-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Dictyostelium discoideum 180691 R-DME-9748969 https://reactome.org/PathwayBrowser/#/R-DME-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Drosophila melanogaster 180691 R-DRE-9748969 https://reactome.org/PathwayBrowser/#/R-DRE-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Danio rerio 180691 R-GGA-9748969 https://reactome.org/PathwayBrowser/#/R-GGA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Gallus gallus 180691 R-GGA-9750555 https://reactome.org/PathwayBrowser/#/R-GGA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Gallus gallus 180691 R-HSA-9748969 https://reactome.org/PathwayBrowser/#/R-HSA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP TAS Homo sapiens 180691 R-HSA-9750555 https://reactome.org/PathwayBrowser/#/R-HSA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP TAS Homo sapiens 180691 R-MMU-9748969 https://reactome.org/PathwayBrowser/#/R-MMU-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Mus musculus 180691 R-MMU-9750555 https://reactome.org/PathwayBrowser/#/R-MMU-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Mus musculus 180691 R-PFA-9748969 https://reactome.org/PathwayBrowser/#/R-PFA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Plasmodium falciparum 180691 R-RNO-9748969 https://reactome.org/PathwayBrowser/#/R-RNO-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Rattus norvegicus 180691 R-RNO-9750555 https://reactome.org/PathwayBrowser/#/R-RNO-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Rattus norvegicus 180691 R-SCE-9748969 https://reactome.org/PathwayBrowser/#/R-SCE-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Saccharomyces cerevisiae 180691 R-SPO-9748969 https://reactome.org/PathwayBrowser/#/R-SPO-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Schizosaccharomyces pombe 180691 R-SSC-9748969 https://reactome.org/PathwayBrowser/#/R-SSC-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Sus scrofa 180691 R-SSC-9750555 https://reactome.org/PathwayBrowser/#/R-SSC-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Sus scrofa 180691 R-XTR-9750555 https://reactome.org/PathwayBrowser/#/R-XTR-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Xenopus tropicalis 180696 R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 180696 R-BTA-9758682 https://reactome.org/PathwayBrowser/#/R-BTA-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Bos taurus 180696 R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 180696 R-CEL-9758682 https://reactome.org/PathwayBrowser/#/R-CEL-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Caenorhabditis elegans 180696 R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 180696 R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 180696 R-DDI-9758682 https://reactome.org/PathwayBrowser/#/R-DDI-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Dictyostelium discoideum 180696 R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 180696 R-DME-9758682 https://reactome.org/PathwayBrowser/#/R-DME-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Drosophila melanogaster 180696 R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 180696 R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 180696 R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 180696 R-HSA-9758682 https://reactome.org/PathwayBrowser/#/R-HSA-9758682 AKR1C1 hydrogenates PREDN,PREDL TAS Homo sapiens 180696 R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 180696 R-MMU-9758682 https://reactome.org/PathwayBrowser/#/R-MMU-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Mus musculus 180696 R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 180696 R-RNO-9758682 https://reactome.org/PathwayBrowser/#/R-RNO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Rattus norvegicus 180696 R-SCE-9758682 https://reactome.org/PathwayBrowser/#/R-SCE-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Saccharomyces cerevisiae 180696 R-SPO-9758682 https://reactome.org/PathwayBrowser/#/R-SPO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Schizosaccharomyces pombe 180696 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 180696 R-SSC-9758682 https://reactome.org/PathwayBrowser/#/R-SSC-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Sus scrofa 180696 R-XTR-9758682 https://reactome.org/PathwayBrowser/#/R-XTR-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Xenopus tropicalis 180697 R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 180697 R-BTA-9758674 https://reactome.org/PathwayBrowser/#/R-BTA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Bos taurus 180697 R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 180697 R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 180697 R-CFA-9758674 https://reactome.org/PathwayBrowser/#/R-CFA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Canis familiaris 180697 R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 180697 R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 180697 R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 180697 R-DRE-9758674 https://reactome.org/PathwayBrowser/#/R-DRE-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Danio rerio 180697 R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 180697 R-GGA-9758674 https://reactome.org/PathwayBrowser/#/R-GGA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Gallus gallus 180697 R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 180697 R-HSA-9758674 https://reactome.org/PathwayBrowser/#/R-HSA-9758674 CYP3A4 oxidizes PREDN,PREDL TAS Homo sapiens 180697 R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 180697 R-MMU-9758674 https://reactome.org/PathwayBrowser/#/R-MMU-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Mus musculus 180697 R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 180697 R-RNO-9758674 https://reactome.org/PathwayBrowser/#/R-RNO-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Rattus norvegicus 180697 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 180697 R-SSC-9758674 https://reactome.org/PathwayBrowser/#/R-SSC-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Sus scrofa 180697 R-XTR-9758674 https://reactome.org/PathwayBrowser/#/R-XTR-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Xenopus tropicalis 18085 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 18085 R-BTA-140696 https://reactome.org/PathwayBrowser/#/R-BTA-140696 factor V -> factor Va + factor V activation peptide IEA Bos taurus 18085 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 18085 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 18085 R-BTA-5578883 https://reactome.org/PathwayBrowser/#/R-BTA-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Bos taurus 18085 R-BTA-5591086 https://reactome.org/PathwayBrowser/#/R-BTA-5591086 SERPINA5 binds activated protein C IEA Bos taurus 18085 R-BTA-5602080 https://reactome.org/PathwayBrowser/#/R-BTA-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Bos taurus 18085 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 18085 R-CFA-140696 https://reactome.org/PathwayBrowser/#/R-CFA-140696 factor V -> factor Va + factor V activation peptide IEA Canis familiaris 18085 R-CFA-5578883 https://reactome.org/PathwayBrowser/#/R-CFA-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Canis familiaris 18085 R-CFA-5591086 https://reactome.org/PathwayBrowser/#/R-CFA-5591086 SERPINA5 binds activated protein C IEA Canis familiaris 18085 R-CFA-5602080 https://reactome.org/PathwayBrowser/#/R-CFA-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Canis familiaris 18085 R-DRE-5591086 https://reactome.org/PathwayBrowser/#/R-DRE-5591086 SERPINA5 binds activated protein C IEA Danio rerio 18085 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 18085 R-GGA-140696 https://reactome.org/PathwayBrowser/#/R-GGA-140696 factor V -> factor Va + factor V activation peptide IEA Gallus gallus 18085 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 18085 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 18085 R-GGA-5578883 https://reactome.org/PathwayBrowser/#/R-GGA-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Gallus gallus 18085 R-GGA-5602080 https://reactome.org/PathwayBrowser/#/R-GGA-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Gallus gallus 18085 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 18085 R-HSA-140696 https://reactome.org/PathwayBrowser/#/R-HSA-140696 factor V -> factor Va + factor V activation peptide TAS Homo sapiens 18085 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 18085 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 18085 R-HSA-5578883 https://reactome.org/PathwayBrowser/#/R-HSA-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) TAS Homo sapiens 18085 R-HSA-5591086 https://reactome.org/PathwayBrowser/#/R-HSA-5591086 SERPINA5 binds activated protein C TAS Homo sapiens 18085 R-HSA-5602080 https://reactome.org/PathwayBrowser/#/R-HSA-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. TAS Homo sapiens 18085 R-HSA-976734 https://reactome.org/PathwayBrowser/#/R-HSA-976734 Amyloid fibrils have additional components TAS Homo sapiens 18085 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 18085 R-MMU-140696 https://reactome.org/PathwayBrowser/#/R-MMU-140696 factor V -> factor Va + factor V activation peptide IEA Mus musculus 18085 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 18085 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 18085 R-MMU-5578883 https://reactome.org/PathwayBrowser/#/R-MMU-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Mus musculus 18085 R-MMU-5591086 https://reactome.org/PathwayBrowser/#/R-MMU-5591086 SERPINA5 binds activated protein C IEA Mus musculus 18085 R-MMU-5602080 https://reactome.org/PathwayBrowser/#/R-MMU-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Mus musculus 18085 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 18085 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 18085 R-RNO-5578883 https://reactome.org/PathwayBrowser/#/R-RNO-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Rattus norvegicus 18085 R-RNO-5591086 https://reactome.org/PathwayBrowser/#/R-RNO-5591086 SERPINA5 binds activated protein C IEA Rattus norvegicus 18085 R-RNO-5602080 https://reactome.org/PathwayBrowser/#/R-RNO-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Rattus norvegicus 18085 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 18085 R-SSC-140696 https://reactome.org/PathwayBrowser/#/R-SSC-140696 factor V -> factor Va + factor V activation peptide IEA Sus scrofa 18085 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 18085 R-SSC-5578883 https://reactome.org/PathwayBrowser/#/R-SSC-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Sus scrofa 18085 R-SSC-5591086 https://reactome.org/PathwayBrowser/#/R-SSC-5591086 SERPINA5 binds activated protein C IEA Sus scrofa 18085 R-SSC-5602080 https://reactome.org/PathwayBrowser/#/R-SSC-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Sus scrofa 18085 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 18085 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 18085 R-XTR-5578883 https://reactome.org/PathwayBrowser/#/R-XTR-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Xenopus tropicalis 18085 R-XTR-5591086 https://reactome.org/PathwayBrowser/#/R-XTR-5591086 SERPINA5 binds activated protein C IEA Xenopus tropicalis 18085 R-XTR-5602080 https://reactome.org/PathwayBrowser/#/R-XTR-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Xenopus tropicalis 18090 R-BTA-141341 https://reactome.org/PathwayBrowser/#/R-BTA-141341 SMOX-3 oxidises SPN to SPM IEA Bos taurus 18090 R-CFA-141341 https://reactome.org/PathwayBrowser/#/R-CFA-141341 SMOX-3 oxidises SPN to SPM IEA Canis familiaris 18090 R-DME-141341 https://reactome.org/PathwayBrowser/#/R-DME-141341 SMOX-3 oxidises SPN to SPM IEA Drosophila melanogaster 18090 R-GGA-141341 https://reactome.org/PathwayBrowser/#/R-GGA-141341 SMOX-3 oxidises SPN to SPM IEA Gallus gallus 18090 R-HSA-141341 https://reactome.org/PathwayBrowser/#/R-HSA-141341 SMOX-3 oxidises SPN to SPM TAS Homo sapiens 18090 R-MMU-141341 https://reactome.org/PathwayBrowser/#/R-MMU-141341 SMOX-3 oxidises SPN to SPM IEA Mus musculus 18090 R-RNO-141341 https://reactome.org/PathwayBrowser/#/R-RNO-141341 SMOX-3 oxidises SPN to SPM IEA Rattus norvegicus 18090 R-SSC-141341 https://reactome.org/PathwayBrowser/#/R-SSC-141341 SMOX-3 oxidises SPN to SPM IEA Sus scrofa 18090 R-XTR-141341 https://reactome.org/PathwayBrowser/#/R-XTR-141341 SMOX-3 oxidises SPN to SPM IEA Xenopus tropicalis 180930 R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 180930 R-BTA-9758674 https://reactome.org/PathwayBrowser/#/R-BTA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Bos taurus 180930 R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 180930 R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 180930 R-CFA-9758674 https://reactome.org/PathwayBrowser/#/R-CFA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Canis familiaris 180930 R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 180930 R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 180930 R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 180930 R-DRE-9758674 https://reactome.org/PathwayBrowser/#/R-DRE-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Danio rerio 180930 R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 180930 R-GGA-9758674 https://reactome.org/PathwayBrowser/#/R-GGA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Gallus gallus 180930 R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 180930 R-HSA-9758674 https://reactome.org/PathwayBrowser/#/R-HSA-9758674 CYP3A4 oxidizes PREDN,PREDL TAS Homo sapiens 180930 R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 180930 R-MMU-9758674 https://reactome.org/PathwayBrowser/#/R-MMU-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Mus musculus 180930 R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 180930 R-RNO-9758674 https://reactome.org/PathwayBrowser/#/R-RNO-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Rattus norvegicus 180930 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 180930 R-SSC-9758674 https://reactome.org/PathwayBrowser/#/R-SSC-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Sus scrofa 180930 R-XTR-9758674 https://reactome.org/PathwayBrowser/#/R-XTR-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Xenopus tropicalis 180931 R-BTA-9748996 https://reactome.org/PathwayBrowser/#/R-BTA-9748996 GST dimers cleave AZA to 6MP IEA Bos taurus 180931 R-CFA-9748996 https://reactome.org/PathwayBrowser/#/R-CFA-9748996 GST dimers cleave AZA to 6MP IEA Canis familiaris 180931 R-DDI-9748996 https://reactome.org/PathwayBrowser/#/R-DDI-9748996 GST dimers cleave AZA to 6MP IEA Dictyostelium discoideum 180931 R-DRE-9748996 https://reactome.org/PathwayBrowser/#/R-DRE-9748996 GST dimers cleave AZA to 6MP IEA Danio rerio 180931 R-GGA-9748996 https://reactome.org/PathwayBrowser/#/R-GGA-9748996 GST dimers cleave AZA to 6MP IEA Gallus gallus 180931 R-HSA-9748996 https://reactome.org/PathwayBrowser/#/R-HSA-9748996 GST dimers cleave AZA to 6MP TAS Homo sapiens 180931 R-HSA-9751051 https://reactome.org/PathwayBrowser/#/R-HSA-9751051 GSH cleaves AZA to 6MP TAS Homo sapiens 180931 R-MMU-9748996 https://reactome.org/PathwayBrowser/#/R-MMU-9748996 GST dimers cleave AZA to 6MP IEA Mus musculus 180931 R-PFA-9748996 https://reactome.org/PathwayBrowser/#/R-PFA-9748996 GST dimers cleave AZA to 6MP IEA Plasmodium falciparum 180931 R-RNO-9748996 https://reactome.org/PathwayBrowser/#/R-RNO-9748996 GST dimers cleave AZA to 6MP IEA Rattus norvegicus 180931 R-SSC-9748996 https://reactome.org/PathwayBrowser/#/R-SSC-9748996 GST dimers cleave AZA to 6MP IEA Sus scrofa 180931 R-XTR-9748996 https://reactome.org/PathwayBrowser/#/R-XTR-9748996 GST dimers cleave AZA to 6MP IEA Xenopus tropicalis 180932 R-BTA-9756134 https://reactome.org/PathwayBrowser/#/R-BTA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Bos taurus 180932 R-BTA-9756138 https://reactome.org/PathwayBrowser/#/R-BTA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Bos taurus 180932 R-BTA-9757139 https://reactome.org/PathwayBrowser/#/R-BTA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Bos taurus 180932 R-CEL-9757139 https://reactome.org/PathwayBrowser/#/R-CEL-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Caenorhabditis elegans 180932 R-CFA-9756138 https://reactome.org/PathwayBrowser/#/R-CFA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Canis familiaris 180932 R-CFA-9757139 https://reactome.org/PathwayBrowser/#/R-CFA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Canis familiaris 180932 R-DDI-9756134 https://reactome.org/PathwayBrowser/#/R-DDI-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Dictyostelium discoideum 180932 R-DDI-9757139 https://reactome.org/PathwayBrowser/#/R-DDI-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Dictyostelium discoideum 180932 R-DME-9757139 https://reactome.org/PathwayBrowser/#/R-DME-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Drosophila melanogaster 180932 R-DRE-9756138 https://reactome.org/PathwayBrowser/#/R-DRE-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Danio rerio 180932 R-DRE-9757139 https://reactome.org/PathwayBrowser/#/R-DRE-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Danio rerio 180932 R-GGA-9756134 https://reactome.org/PathwayBrowser/#/R-GGA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Gallus gallus 180932 R-GGA-9756138 https://reactome.org/PathwayBrowser/#/R-GGA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Gallus gallus 180932 R-GGA-9757139 https://reactome.org/PathwayBrowser/#/R-GGA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Gallus gallus 180932 R-HSA-9756134 https://reactome.org/PathwayBrowser/#/R-HSA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL TAS Homo sapiens 180932 R-HSA-9756136 https://reactome.org/PathwayBrowser/#/R-HSA-9756136 PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV IEA Homo sapiens 180932 R-HSA-9756138 https://reactome.org/PathwayBrowser/#/R-HSA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL TAS Homo sapiens 180932 R-HSA-9757139 https://reactome.org/PathwayBrowser/#/R-HSA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region TAS Homo sapiens 180932 R-MMU-9756134 https://reactome.org/PathwayBrowser/#/R-MMU-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Mus musculus 180932 R-MMU-9756138 https://reactome.org/PathwayBrowser/#/R-MMU-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Mus musculus 180932 R-MMU-9757139 https://reactome.org/PathwayBrowser/#/R-MMU-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Mus musculus 180932 R-PFA-9757139 https://reactome.org/PathwayBrowser/#/R-PFA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Plasmodium falciparum 180932 R-RNO-9756134 https://reactome.org/PathwayBrowser/#/R-RNO-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Rattus norvegicus 180932 R-RNO-9756138 https://reactome.org/PathwayBrowser/#/R-RNO-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Rattus norvegicus 180932 R-RNO-9757139 https://reactome.org/PathwayBrowser/#/R-RNO-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Rattus norvegicus 180932 R-SCE-9757139 https://reactome.org/PathwayBrowser/#/R-SCE-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Saccharomyces cerevisiae 180932 R-SPO-9757139 https://reactome.org/PathwayBrowser/#/R-SPO-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Schizosaccharomyces pombe 180932 R-SSC-9756134 https://reactome.org/PathwayBrowser/#/R-SSC-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Sus scrofa 180932 R-SSC-9756138 https://reactome.org/PathwayBrowser/#/R-SSC-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Sus scrofa 180932 R-SSC-9757139 https://reactome.org/PathwayBrowser/#/R-SSC-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Sus scrofa 180932 R-XTR-9756138 https://reactome.org/PathwayBrowser/#/R-XTR-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Xenopus tropicalis 180932 R-XTR-9757139 https://reactome.org/PathwayBrowser/#/R-XTR-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Xenopus tropicalis 180934 R-BTA-9756180 https://reactome.org/PathwayBrowser/#/R-BTA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Bos taurus 180934 R-BTA-9756183 https://reactome.org/PathwayBrowser/#/R-BTA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Bos taurus 180934 R-BTA-9757139 https://reactome.org/PathwayBrowser/#/R-BTA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Bos taurus 180934 R-CEL-9757139 https://reactome.org/PathwayBrowser/#/R-CEL-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Caenorhabditis elegans 180934 R-CFA-9756180 https://reactome.org/PathwayBrowser/#/R-CFA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Canis familiaris 180934 R-CFA-9757139 https://reactome.org/PathwayBrowser/#/R-CFA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Canis familiaris 180934 R-DDI-9756183 https://reactome.org/PathwayBrowser/#/R-DDI-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Dictyostelium discoideum 180934 R-DDI-9757139 https://reactome.org/PathwayBrowser/#/R-DDI-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Dictyostelium discoideum 180934 R-DME-9757139 https://reactome.org/PathwayBrowser/#/R-DME-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Drosophila melanogaster 180934 R-DRE-9756180 https://reactome.org/PathwayBrowser/#/R-DRE-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Danio rerio 180934 R-DRE-9757139 https://reactome.org/PathwayBrowser/#/R-DRE-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Danio rerio 180934 R-GGA-9756180 https://reactome.org/PathwayBrowser/#/R-GGA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Gallus gallus 180934 R-GGA-9756183 https://reactome.org/PathwayBrowser/#/R-GGA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Gallus gallus 180934 R-GGA-9757139 https://reactome.org/PathwayBrowser/#/R-GGA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Gallus gallus 180934 R-HSA-9756150 https://reactome.org/PathwayBrowser/#/R-HSA-9756150 PON1,3 hydrolyse 4-OH-ATVL to 4-OH-ATV IEA Homo sapiens 180934 R-HSA-9756180 https://reactome.org/PathwayBrowser/#/R-HSA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL TAS Homo sapiens 180934 R-HSA-9756183 https://reactome.org/PathwayBrowser/#/R-HSA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL TAS Homo sapiens 180934 R-HSA-9757139 https://reactome.org/PathwayBrowser/#/R-HSA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region TAS Homo sapiens 180934 R-MMU-9756180 https://reactome.org/PathwayBrowser/#/R-MMU-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Mus musculus 180934 R-MMU-9756183 https://reactome.org/PathwayBrowser/#/R-MMU-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Mus musculus 180934 R-MMU-9757139 https://reactome.org/PathwayBrowser/#/R-MMU-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Mus musculus 180934 R-PFA-9757139 https://reactome.org/PathwayBrowser/#/R-PFA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Plasmodium falciparum 180934 R-RNO-9756180 https://reactome.org/PathwayBrowser/#/R-RNO-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Rattus norvegicus 180934 R-RNO-9756183 https://reactome.org/PathwayBrowser/#/R-RNO-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Rattus norvegicus 180934 R-RNO-9757139 https://reactome.org/PathwayBrowser/#/R-RNO-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Rattus norvegicus 180934 R-SCE-9757139 https://reactome.org/PathwayBrowser/#/R-SCE-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Saccharomyces cerevisiae 180934 R-SPO-9757139 https://reactome.org/PathwayBrowser/#/R-SPO-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Schizosaccharomyces pombe 180934 R-SSC-9756180 https://reactome.org/PathwayBrowser/#/R-SSC-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Sus scrofa 180934 R-SSC-9756183 https://reactome.org/PathwayBrowser/#/R-SSC-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Sus scrofa 180934 R-SSC-9757139 https://reactome.org/PathwayBrowser/#/R-SSC-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Sus scrofa 180934 R-XTR-9756180 https://reactome.org/PathwayBrowser/#/R-XTR-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Xenopus tropicalis 180934 R-XTR-9757139 https://reactome.org/PathwayBrowser/#/R-XTR-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Xenopus tropicalis 18097 R-BTA-5690565 https://reactome.org/PathwayBrowser/#/R-BTA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Bos taurus 18097 R-BTA-8847579 https://reactome.org/PathwayBrowser/#/R-BTA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Bos taurus 18097 R-CEL-5690565 https://reactome.org/PathwayBrowser/#/R-CEL-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 18097 R-CEL-8847579 https://reactome.org/PathwayBrowser/#/R-CEL-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 18097 R-CFA-5690565 https://reactome.org/PathwayBrowser/#/R-CFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Canis familiaris 18097 R-CFA-8847579 https://reactome.org/PathwayBrowser/#/R-CFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Canis familiaris 18097 R-DDI-5690565 https://reactome.org/PathwayBrowser/#/R-DDI-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 18097 R-DDI-8847579 https://reactome.org/PathwayBrowser/#/R-DDI-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 18097 R-DME-5690565 https://reactome.org/PathwayBrowser/#/R-DME-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 18097 R-DME-8847579 https://reactome.org/PathwayBrowser/#/R-DME-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 18097 R-DRE-5690565 https://reactome.org/PathwayBrowser/#/R-DRE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Danio rerio 18097 R-GGA-5690565 https://reactome.org/PathwayBrowser/#/R-GGA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Gallus gallus 18097 R-GGA-8847579 https://reactome.org/PathwayBrowser/#/R-GGA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Gallus gallus 18097 R-HSA-5690565 https://reactome.org/PathwayBrowser/#/R-HSA-5690565 SCD desaturates ST-CoA to OLE-CoA TAS Homo sapiens 18097 R-HSA-8847579 https://reactome.org/PathwayBrowser/#/R-HSA-8847579 SCD5 desaturates ST-CoA to OLE-CoA TAS Homo sapiens 18097 R-MMU-5690565 https://reactome.org/PathwayBrowser/#/R-MMU-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Mus musculus 18097 R-PFA-5690565 https://reactome.org/PathwayBrowser/#/R-PFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 18097 R-PFA-8847579 https://reactome.org/PathwayBrowser/#/R-PFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 18097 R-RNO-5690565 https://reactome.org/PathwayBrowser/#/R-RNO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Rattus norvegicus 18097 R-SCE-5690565 https://reactome.org/PathwayBrowser/#/R-SCE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 18097 R-SCE-8847579 https://reactome.org/PathwayBrowser/#/R-SCE-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 18097 R-SPO-5690565 https://reactome.org/PathwayBrowser/#/R-SPO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 18097 R-SPO-8847579 https://reactome.org/PathwayBrowser/#/R-SPO-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 18097 R-SSC-5690565 https://reactome.org/PathwayBrowser/#/R-SSC-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Sus scrofa 18097 R-SSC-8847579 https://reactome.org/PathwayBrowser/#/R-SSC-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Sus scrofa 18097 R-XTR-5690565 https://reactome.org/PathwayBrowser/#/R-XTR-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Xenopus tropicalis 18105 R-CFA-170799 https://reactome.org/PathwayBrowser/#/R-CFA-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Canis familiaris 18105 R-CFA-170824 https://reactome.org/PathwayBrowser/#/R-CFA-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Canis familiaris 18105 R-HSA-170799 https://reactome.org/PathwayBrowser/#/R-HSA-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) TAS Homo sapiens 18105 R-HSA-170824 https://reactome.org/PathwayBrowser/#/R-HSA-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex TAS Homo sapiens 18105 R-HSA-5656438 https://reactome.org/PathwayBrowser/#/R-HSA-5656438 Defective ALDOB does not cleave Fru 1-P to GA and DHAP TAS Homo sapiens 18105 R-MMU-170799 https://reactome.org/PathwayBrowser/#/R-MMU-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Mus musculus 18105 R-MMU-170824 https://reactome.org/PathwayBrowser/#/R-MMU-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Mus musculus 18105 R-RNO-170799 https://reactome.org/PathwayBrowser/#/R-RNO-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Rattus norvegicus 18105 R-RNO-170824 https://reactome.org/PathwayBrowser/#/R-RNO-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Rattus norvegicus 18105 R-XTR-170799 https://reactome.org/PathwayBrowser/#/R-XTR-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Xenopus tropicalis 18105 R-XTR-170824 https://reactome.org/PathwayBrowser/#/R-XTR-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Xenopus tropicalis 18111 R-HSA-6790906 https://reactome.org/PathwayBrowser/#/R-HSA-6790906 EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 IEA Homo sapiens 18111 R-HSA-6790982 https://reactome.org/PathwayBrowser/#/R-HSA-6790982 WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639 TAS Homo sapiens 18111 R-HSA-6790987 https://reactome.org/PathwayBrowser/#/R-HSA-6790987 NAT10 acetylates cytidine-1337 and cytidine-1842 of 18S rRNA yielding 4-acetylcytidine-1377 and 4-acetylcytidine-1842 TAS Homo sapiens 18111 R-HSA-6790994 https://reactome.org/PathwayBrowser/#/R-HSA-6790994 DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851 TAS Homo sapiens 18111 R-HSA-6791218 https://reactome.org/PathwayBrowser/#/R-HSA-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA TAS Homo sapiens 18111 R-HSA-6791219 https://reactome.org/PathwayBrowser/#/R-HSA-6791219 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA TAS Homo sapiens 18111 R-HSA-6791221 https://reactome.org/PathwayBrowser/#/R-HSA-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA TAS Homo sapiens 18111 R-HSA-6791222 https://reactome.org/PathwayBrowser/#/R-HSA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA TAS Homo sapiens 18111 R-HSA-6791223 https://reactome.org/PathwayBrowser/#/R-HSA-6791223 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol TAS Homo sapiens 18111 R-HSA-6791227 https://reactome.org/PathwayBrowser/#/R-HSA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA TAS Homo sapiens 18111 R-HSA-6791228 https://reactome.org/PathwayBrowser/#/R-HSA-6791228 45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA TAS Homo sapiens 18111 R-HSA-8868783 https://reactome.org/PathwayBrowser/#/R-HSA-8868783 TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248 TAS Homo sapiens 18116 R-BTA-6788295 https://reactome.org/PathwayBrowser/#/R-BTA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Bos taurus 18116 R-CEL-6788295 https://reactome.org/PathwayBrowser/#/R-CEL-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Caenorhabditis elegans 18116 R-CFA-6788295 https://reactome.org/PathwayBrowser/#/R-CFA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Canis familiaris 18116 R-DME-6788295 https://reactome.org/PathwayBrowser/#/R-DME-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Drosophila melanogaster 18116 R-DRE-6788295 https://reactome.org/PathwayBrowser/#/R-DRE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Danio rerio 18116 R-GGA-6788295 https://reactome.org/PathwayBrowser/#/R-GGA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Gallus gallus 18116 R-HSA-6788295 https://reactome.org/PathwayBrowser/#/R-HSA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP TAS Homo sapiens 18116 R-MMU-6788295 https://reactome.org/PathwayBrowser/#/R-MMU-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Mus musculus 18116 R-RNO-6788295 https://reactome.org/PathwayBrowser/#/R-RNO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Rattus norvegicus 18116 R-SCE-6788295 https://reactome.org/PathwayBrowser/#/R-SCE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Saccharomyces cerevisiae 18116 R-SPO-6788295 https://reactome.org/PathwayBrowser/#/R-SPO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Schizosaccharomyces pombe 18116 R-SSC-6788295 https://reactome.org/PathwayBrowser/#/R-SSC-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Sus scrofa 18116 R-XTR-6788295 https://reactome.org/PathwayBrowser/#/R-XTR-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Xenopus tropicalis 18132 R-BTA-1606288 https://reactome.org/PathwayBrowser/#/R-BTA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Bos taurus 18132 R-BTA-6814797 https://reactome.org/PathwayBrowser/#/R-BTA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Bos taurus 18132 R-CEL-1606288 https://reactome.org/PathwayBrowser/#/R-CEL-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Caenorhabditis elegans 18132 R-CEL-6814797 https://reactome.org/PathwayBrowser/#/R-CEL-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Caenorhabditis elegans 18132 R-CFA-1606288 https://reactome.org/PathwayBrowser/#/R-CFA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Canis familiaris 18132 R-CFA-6814797 https://reactome.org/PathwayBrowser/#/R-CFA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Canis familiaris 18132 R-DDI-6814797 https://reactome.org/PathwayBrowser/#/R-DDI-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Dictyostelium discoideum 18132 R-DME-1606288 https://reactome.org/PathwayBrowser/#/R-DME-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Drosophila melanogaster 18132 R-DRE-1606288 https://reactome.org/PathwayBrowser/#/R-DRE-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Danio rerio 18132 R-DRE-6814797 https://reactome.org/PathwayBrowser/#/R-DRE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Danio rerio 18132 R-GGA-1606288 https://reactome.org/PathwayBrowser/#/R-GGA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Gallus gallus 18132 R-GGA-6814797 https://reactome.org/PathwayBrowser/#/R-GGA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Gallus gallus 18132 R-HSA-1606288 https://reactome.org/PathwayBrowser/#/R-HSA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) TAS Homo sapiens 18132 R-HSA-193706 https://reactome.org/PathwayBrowser/#/R-HSA-193706 Production of ceramide which can activate JNK and other targets IEA Homo sapiens 18132 R-HSA-6814797 https://reactome.org/PathwayBrowser/#/R-HSA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine TAS Homo sapiens 18132 R-HSA-9680388 https://reactome.org/PathwayBrowser/#/R-HSA-9680388 CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine IEA Homo sapiens 18132 R-MMU-1606288 https://reactome.org/PathwayBrowser/#/R-MMU-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Mus musculus 18132 R-MMU-6814797 https://reactome.org/PathwayBrowser/#/R-MMU-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Mus musculus 18132 R-MMU-9682158 https://reactome.org/PathwayBrowser/#/R-MMU-9682158 Csf1r-associated Plcg2 hydrolyzes phosphatidylcholine yielding choline phosphate and 1,2-diacylglycerol TAS Mus musculus 18132 R-RNO-1606288 https://reactome.org/PathwayBrowser/#/R-RNO-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Rattus norvegicus 18132 R-RNO-209562 https://reactome.org/PathwayBrowser/#/R-RNO-209562 Production of ceramide which can activate JNK and other targets TAS Rattus norvegicus 18132 R-RNO-6814797 https://reactome.org/PathwayBrowser/#/R-RNO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Rattus norvegicus 18132 R-SCE-6814797 https://reactome.org/PathwayBrowser/#/R-SCE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Saccharomyces cerevisiae 18132 R-SPO-6814797 https://reactome.org/PathwayBrowser/#/R-SPO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Schizosaccharomyces pombe 18132 R-SSC-1606288 https://reactome.org/PathwayBrowser/#/R-SSC-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Sus scrofa 18132 R-SSC-6814797 https://reactome.org/PathwayBrowser/#/R-SSC-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Sus scrofa 18132 R-XTR-6814797 https://reactome.org/PathwayBrowser/#/R-XTR-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Xenopus tropicalis 18139 R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 18139 R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 18139 R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 18139 R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 18139 R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 18139 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 18139 R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 18139 R-HSA-5602966 https://reactome.org/PathwayBrowser/#/R-HSA-5602966 Defective FMO3 does not N-oxidise TMA TAS Homo sapiens 18139 R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 18139 R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 18139 R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 18139 R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 18145 R-BTA-8874705 https://reactome.org/PathwayBrowser/#/R-BTA-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane IEA Bos taurus 18145 R-BTA-8874718 https://reactome.org/PathwayBrowser/#/R-BTA-8874718 TTPA binds alpha-TOH IEA Bos taurus 18145 R-CFA-8874705 https://reactome.org/PathwayBrowser/#/R-CFA-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane IEA Canis familiaris 18145 R-CFA-8874718 https://reactome.org/PathwayBrowser/#/R-CFA-8874718 TTPA binds alpha-TOH IEA Canis familiaris 18145 R-DDI-8874705 https://reactome.org/PathwayBrowser/#/R-DDI-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane IEA Dictyostelium discoideum 18145 R-DDI-8874718 https://reactome.org/PathwayBrowser/#/R-DDI-8874718 TTPA binds alpha-TOH IEA Dictyostelium discoideum 18145 R-DME-8874705 https://reactome.org/PathwayBrowser/#/R-DME-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane IEA Drosophila melanogaster 18145 R-DME-8874718 https://reactome.org/PathwayBrowser/#/R-DME-8874718 TTPA binds alpha-TOH IEA Drosophila melanogaster 18145 R-GGA-8874705 https://reactome.org/PathwayBrowser/#/R-GGA-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane IEA Gallus gallus 18145 R-GGA-8874718 https://reactome.org/PathwayBrowser/#/R-GGA-8874718 TTPA binds alpha-TOH IEA Gallus gallus 18145 R-HSA-8874705 https://reactome.org/PathwayBrowser/#/R-HSA-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane TAS Homo sapiens 18145 R-HSA-8874718 https://reactome.org/PathwayBrowser/#/R-HSA-8874718 TTPA binds alpha-TOH TAS Homo sapiens 18145 R-MMU-8874705 https://reactome.org/PathwayBrowser/#/R-MMU-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane IEA Mus musculus 18145 R-MMU-8874718 https://reactome.org/PathwayBrowser/#/R-MMU-8874718 TTPA binds alpha-TOH IEA Mus musculus 18145 R-RNO-8874705 https://reactome.org/PathwayBrowser/#/R-RNO-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane IEA Rattus norvegicus 18145 R-RNO-8874718 https://reactome.org/PathwayBrowser/#/R-RNO-8874718 TTPA binds alpha-TOH IEA Rattus norvegicus 18145 R-SSC-8874705 https://reactome.org/PathwayBrowser/#/R-SSC-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane IEA Sus scrofa 18145 R-SSC-8874718 https://reactome.org/PathwayBrowser/#/R-SSC-8874718 TTPA binds alpha-TOH IEA Sus scrofa 18148 R-BTA-8955760 https://reactome.org/PathwayBrowser/#/R-BTA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Bos taurus 18148 R-CEL-8955760 https://reactome.org/PathwayBrowser/#/R-CEL-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Caenorhabditis elegans 18148 R-CFA-8955760 https://reactome.org/PathwayBrowser/#/R-CFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Canis familiaris 18148 R-DDI-8955760 https://reactome.org/PathwayBrowser/#/R-DDI-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Dictyostelium discoideum 18148 R-DME-8955760 https://reactome.org/PathwayBrowser/#/R-DME-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Drosophila melanogaster 18148 R-DRE-8955760 https://reactome.org/PathwayBrowser/#/R-DRE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Danio rerio 18148 R-GGA-8955760 https://reactome.org/PathwayBrowser/#/R-GGA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Gallus gallus 18148 R-HSA-8955760 https://reactome.org/PathwayBrowser/#/R-HSA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP TAS Homo sapiens 18148 R-MMU-8955760 https://reactome.org/PathwayBrowser/#/R-MMU-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Mus musculus 18148 R-PFA-8955760 https://reactome.org/PathwayBrowser/#/R-PFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Plasmodium falciparum 18148 R-RNO-8955760 https://reactome.org/PathwayBrowser/#/R-RNO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Rattus norvegicus 18148 R-RNO-9769759 https://reactome.org/PathwayBrowser/#/R-RNO-9769759 Npas4 translocates to the nucleus TAS Rattus norvegicus 18148 R-SCE-8955760 https://reactome.org/PathwayBrowser/#/R-SCE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Saccharomyces cerevisiae 18148 R-SPO-8955760 https://reactome.org/PathwayBrowser/#/R-SPO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Schizosaccharomyces pombe 18148 R-SSC-8955760 https://reactome.org/PathwayBrowser/#/R-SSC-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Sus scrofa 18148 R-XTR-8955760 https://reactome.org/PathwayBrowser/#/R-XTR-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Xenopus tropicalis 18153 R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 18153 R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 18153 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 18153 R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 18153 R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 18153 R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 18153 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 18169 R-BTA-1855178 https://reactome.org/PathwayBrowser/#/R-BTA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Bos taurus 18169 R-BTA-1855202 https://reactome.org/PathwayBrowser/#/R-BTA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Bos taurus 18169 R-BTA-1855210 https://reactome.org/PathwayBrowser/#/R-BTA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 18169 R-CEL-1855178 https://reactome.org/PathwayBrowser/#/R-CEL-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Caenorhabditis elegans 18169 R-CEL-1855202 https://reactome.org/PathwayBrowser/#/R-CEL-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Caenorhabditis elegans 18169 R-CEL-1855210 https://reactome.org/PathwayBrowser/#/R-CEL-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 18169 R-CFA-1855202 https://reactome.org/PathwayBrowser/#/R-CFA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Canis familiaris 18169 R-CFA-1855210 https://reactome.org/PathwayBrowser/#/R-CFA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 18169 R-DDI-1855178 https://reactome.org/PathwayBrowser/#/R-DDI-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Dictyostelium discoideum 18169 R-DDI-1855210 https://reactome.org/PathwayBrowser/#/R-DDI-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 18169 R-DME-1855178 https://reactome.org/PathwayBrowser/#/R-DME-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Drosophila melanogaster 18169 R-DME-1855202 https://reactome.org/PathwayBrowser/#/R-DME-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Drosophila melanogaster 18169 R-DME-1855210 https://reactome.org/PathwayBrowser/#/R-DME-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 18169 R-DRE-1855202 https://reactome.org/PathwayBrowser/#/R-DRE-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Danio rerio 18169 R-DRE-1855210 https://reactome.org/PathwayBrowser/#/R-DRE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 18169 R-GGA-1855178 https://reactome.org/PathwayBrowser/#/R-GGA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Gallus gallus 18169 R-GGA-1855202 https://reactome.org/PathwayBrowser/#/R-GGA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Gallus gallus 18169 R-GGA-1855210 https://reactome.org/PathwayBrowser/#/R-GGA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 18169 R-HSA-1855178 https://reactome.org/PathwayBrowser/#/R-HSA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol TAS Homo sapiens 18169 R-HSA-1855202 https://reactome.org/PathwayBrowser/#/R-HSA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol TAS Homo sapiens 18169 R-HSA-1855210 https://reactome.org/PathwayBrowser/#/R-HSA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 18169 R-MMU-1855178 https://reactome.org/PathwayBrowser/#/R-MMU-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Mus musculus 18169 R-MMU-1855202 https://reactome.org/PathwayBrowser/#/R-MMU-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Mus musculus 18169 R-MMU-1855210 https://reactome.org/PathwayBrowser/#/R-MMU-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 18169 R-PFA-1855178 https://reactome.org/PathwayBrowser/#/R-PFA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Plasmodium falciparum 18169 R-RNO-1855178 https://reactome.org/PathwayBrowser/#/R-RNO-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Rattus norvegicus 18169 R-RNO-1855202 https://reactome.org/PathwayBrowser/#/R-RNO-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Rattus norvegicus 18169 R-RNO-1855210 https://reactome.org/PathwayBrowser/#/R-RNO-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 18169 R-SCE-1855178 https://reactome.org/PathwayBrowser/#/R-SCE-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Saccharomyces cerevisiae 18169 R-SCE-1855210 https://reactome.org/PathwayBrowser/#/R-SCE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 18169 R-SSC-1855178 https://reactome.org/PathwayBrowser/#/R-SSC-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Sus scrofa 18169 R-SSC-1855202 https://reactome.org/PathwayBrowser/#/R-SSC-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Sus scrofa 18169 R-SSC-1855210 https://reactome.org/PathwayBrowser/#/R-SSC-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 18169 R-XTR-1855178 https://reactome.org/PathwayBrowser/#/R-XTR-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Xenopus tropicalis 18169 R-XTR-1855202 https://reactome.org/PathwayBrowser/#/R-XTR-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Xenopus tropicalis 18169 R-XTR-1855210 https://reactome.org/PathwayBrowser/#/R-XTR-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 18170 R-HSA-2408525 https://reactome.org/PathwayBrowser/#/R-HSA-2408525 H2SeO4 is converted to APSe by PAPSS1,2 IEA Homo sapiens 18170 R-RNO-2408504 https://reactome.org/PathwayBrowser/#/R-RNO-2408504 H2SeO4 is converted to APSe by PAPSS1,2 TAS Rattus norvegicus 18191 R-HSA-2161612 https://reactome.org/PathwayBrowser/#/R-HSA-2161612 PGH2 is reduced to PGF2a by FAM213B IEA Homo sapiens 18191 R-MMU-2161718 https://reactome.org/PathwayBrowser/#/R-MMU-2161718 PGH2 is reduced to PGF2a by Fam213b TAS Mus musculus 18205 R-BTA-446201 https://reactome.org/PathwayBrowser/#/R-BTA-446201 PMM1,2 isomerise Man6P to Man1P IEA Bos taurus 18205 R-CEL-446201 https://reactome.org/PathwayBrowser/#/R-CEL-446201 PMM1,2 isomerise Man6P to Man1P IEA Caenorhabditis elegans 18205 R-CFA-446201 https://reactome.org/PathwayBrowser/#/R-CFA-446201 PMM1,2 isomerise Man6P to Man1P IEA Canis familiaris 18205 R-DDI-446201 https://reactome.org/PathwayBrowser/#/R-DDI-446201 PMM1,2 isomerise Man6P to Man1P IEA Dictyostelium discoideum 18205 R-DME-446201 https://reactome.org/PathwayBrowser/#/R-DME-446201 PMM1,2 isomerise Man6P to Man1P IEA Drosophila melanogaster 18205 R-DRE-446201 https://reactome.org/PathwayBrowser/#/R-DRE-446201 PMM1,2 isomerise Man6P to Man1P IEA Danio rerio 18205 R-GGA-446201 https://reactome.org/PathwayBrowser/#/R-GGA-446201 PMM1,2 isomerise Man6P to Man1P IEA Gallus gallus 18205 R-HSA-446201 https://reactome.org/PathwayBrowser/#/R-HSA-446201 PMM1,2 isomerise Man6P to Man1P TAS Homo sapiens 18205 R-HSA-446221 https://reactome.org/PathwayBrowser/#/R-HSA-446221 Mannose-1-phosphate converted to GDP-Mannose IEA Homo sapiens 18205 R-MMU-446201 https://reactome.org/PathwayBrowser/#/R-MMU-446201 PMM1,2 isomerise Man6P to Man1P IEA Mus musculus 18205 R-PFA-446201 https://reactome.org/PathwayBrowser/#/R-PFA-446201 PMM1,2 isomerise Man6P to Man1P IEA Plasmodium falciparum 18205 R-RNO-446201 https://reactome.org/PathwayBrowser/#/R-RNO-446201 PMM1,2 isomerise Man6P to Man1P IEA Rattus norvegicus 18205 R-RNO-749516 https://reactome.org/PathwayBrowser/#/R-RNO-749516 Mannose-1-phosphate converted to GDP-Mannose TAS Rattus norvegicus 18205 R-SCE-446201 https://reactome.org/PathwayBrowser/#/R-SCE-446201 PMM1,2 isomerise Man6P to Man1P IEA Saccharomyces cerevisiae 18205 R-SPO-446201 https://reactome.org/PathwayBrowser/#/R-SPO-446201 PMM1,2 isomerise Man6P to Man1P IEA Schizosaccharomyces pombe 18205 R-SSC-446201 https://reactome.org/PathwayBrowser/#/R-SSC-446201 PMM1,2 isomerise Man6P to Man1P IEA Sus scrofa 18205 R-XTR-446201 https://reactome.org/PathwayBrowser/#/R-XTR-446201 PMM1,2 isomerise Man6P to Man1P IEA Xenopus tropicalis 18212 R-BTA-2408527 https://reactome.org/PathwayBrowser/#/R-BTA-2408527 SeO3(2-) is reduced to H2Se by TXNRD1 TAS Bos taurus 18212 R-HSA-2408548 https://reactome.org/PathwayBrowser/#/R-HSA-2408548 PAPSe is reduced to SeO3(2-) by PAPSe reductase IEA Homo sapiens 18212 R-HSA-2408556 https://reactome.org/PathwayBrowser/#/R-HSA-2408556 SeO3(2-) combines with GSH to form GSSeSG and GSSG IEA Homo sapiens 18212 R-HSA-2408558 https://reactome.org/PathwayBrowser/#/R-HSA-2408558 SeO3(2-) is reduced to H2Se by TXNRD1 IEA Homo sapiens 18212 R-RNO-2408553 https://reactome.org/PathwayBrowser/#/R-RNO-2408553 SeO3(2-) combines with GSH to form GSSeSG and GSSG TAS Rattus norvegicus 18212 R-SCE-2408518 https://reactome.org/PathwayBrowser/#/R-SCE-2408518 PAPSe is reduced to SeO3(2-) by MET16 TAS Saccharomyces cerevisiae 18216 R-HSA-5228406 https://reactome.org/PathwayBrowser/#/R-HSA-5228406 tetX HC transports tetX LC from target cell endosome membrane into cytosol TAS Homo sapiens 18216 R-HSA-5228407 https://reactome.org/PathwayBrowser/#/R-HSA-5228407 tetX HC:LC binds target cell-surface gangliosides TAS Homo sapiens 18216 R-HSA-5228408 https://reactome.org/PathwayBrowser/#/R-HSA-5228408 Retrograde transport of internalized tetX HC:LC:gangliosides TAS Homo sapiens 18216 R-HSA-5228411 https://reactome.org/PathwayBrowser/#/R-HSA-5228411 Clathrin-mediated endocytosis of tetX HC:LC:gangliosides TAS Homo sapiens 18224 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 18224 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 18224 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 18224 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 18224 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 18224 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 18224 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 18224 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 18224 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 18225 R-BTA-1855180 https://reactome.org/PathwayBrowser/#/R-BTA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Bos taurus 18225 R-CEL-1855180 https://reactome.org/PathwayBrowser/#/R-CEL-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Caenorhabditis elegans 18225 R-CFA-1855180 https://reactome.org/PathwayBrowser/#/R-CFA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Canis familiaris 18225 R-DME-1855180 https://reactome.org/PathwayBrowser/#/R-DME-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Drosophila melanogaster 18225 R-DRE-1855180 https://reactome.org/PathwayBrowser/#/R-DRE-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Danio rerio 18225 R-GGA-1855180 https://reactome.org/PathwayBrowser/#/R-GGA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Gallus gallus 18225 R-HSA-1855180 https://reactome.org/PathwayBrowser/#/R-HSA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol TAS Homo sapiens 18225 R-HSA-6809561 https://reactome.org/PathwayBrowser/#/R-HSA-6809561 I(1,3)P2 is dephosphorylated into I1P by MTMR7 IEA Homo sapiens 18225 R-HSA-6809565 https://reactome.org/PathwayBrowser/#/R-HSA-6809565 I(1,3)P2 is dephosphorylated into I1P by MTMR7:MTMR9 IEA Homo sapiens 18225 R-MMU-1855180 https://reactome.org/PathwayBrowser/#/R-MMU-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Mus musculus 18225 R-MMU-6809624 https://reactome.org/PathwayBrowser/#/R-MMU-6809624 I(1,3)P2 is dephosphorylated into I1P by Mtmr7 TAS Mus musculus 18225 R-MMU-6809627 https://reactome.org/PathwayBrowser/#/R-MMU-6809627 I(1,3)P2 is dephosphorylated into I1P by Mtmr7:Mtmr9 TAS Mus musculus 18225 R-RNO-1855180 https://reactome.org/PathwayBrowser/#/R-RNO-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Rattus norvegicus 18225 R-SSC-1855180 https://reactome.org/PathwayBrowser/#/R-SSC-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Sus scrofa 18225 R-XTR-1855180 https://reactome.org/PathwayBrowser/#/R-XTR-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Xenopus tropicalis 18248 R-HSA-2564826 https://reactome.org/PathwayBrowser/#/R-HSA-2564826 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold IEA Homo sapiens 18248 R-SCE-2564822 https://reactome.org/PathwayBrowser/#/R-SCE-2564822 4Fe-4S cluster assembles on CFD1:NBP35 scaffold TAS Saccharomyces cerevisiae 18252 R-BTA-194632 https://reactome.org/PathwayBrowser/#/R-BTA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Bos taurus 18252 R-BTA-195690 https://reactome.org/PathwayBrowser/#/R-BTA-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Bos taurus 18252 R-BTA-6807064 https://reactome.org/PathwayBrowser/#/R-BTA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Bos taurus 18252 R-CEL-6807064 https://reactome.org/PathwayBrowser/#/R-CEL-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Caenorhabditis elegans 18252 R-CFA-194632 https://reactome.org/PathwayBrowser/#/R-CFA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Canis familiaris 18252 R-CFA-195690 https://reactome.org/PathwayBrowser/#/R-CFA-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Canis familiaris 18252 R-CFA-6807064 https://reactome.org/PathwayBrowser/#/R-CFA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Canis familiaris 18252 R-DDI-195690 https://reactome.org/PathwayBrowser/#/R-DDI-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Dictyostelium discoideum 18252 R-DRE-194632 https://reactome.org/PathwayBrowser/#/R-DRE-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Danio rerio 18252 R-DRE-195690 https://reactome.org/PathwayBrowser/#/R-DRE-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Danio rerio 18252 R-DRE-6807064 https://reactome.org/PathwayBrowser/#/R-DRE-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Danio rerio 18252 R-GGA-194632 https://reactome.org/PathwayBrowser/#/R-GGA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Gallus gallus 18252 R-GGA-195690 https://reactome.org/PathwayBrowser/#/R-GGA-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Gallus gallus 18252 R-GGA-6807064 https://reactome.org/PathwayBrowser/#/R-GGA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Gallus gallus 18252 R-HSA-194632 https://reactome.org/PathwayBrowser/#/R-HSA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) TAS Homo sapiens 18252 R-HSA-195690 https://reactome.org/PathwayBrowser/#/R-HSA-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol TAS Homo sapiens 18252 R-HSA-6807064 https://reactome.org/PathwayBrowser/#/R-HSA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL TAS Homo sapiens 18252 R-MMU-194632 https://reactome.org/PathwayBrowser/#/R-MMU-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Mus musculus 18252 R-MMU-195690 https://reactome.org/PathwayBrowser/#/R-MMU-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Mus musculus 18252 R-MMU-6807064 https://reactome.org/PathwayBrowser/#/R-MMU-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Mus musculus 18252 R-RNO-194632 https://reactome.org/PathwayBrowser/#/R-RNO-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Rattus norvegicus 18252 R-RNO-195690 https://reactome.org/PathwayBrowser/#/R-RNO-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Rattus norvegicus 18252 R-RNO-6807064 https://reactome.org/PathwayBrowser/#/R-RNO-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Rattus norvegicus 18252 R-SSC-194632 https://reactome.org/PathwayBrowser/#/R-SSC-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Sus scrofa 18252 R-SSC-195690 https://reactome.org/PathwayBrowser/#/R-SSC-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol IEA Sus scrofa 18252 R-SSC-6807064 https://reactome.org/PathwayBrowser/#/R-SSC-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Sus scrofa 18252 R-XTR-6807064 https://reactome.org/PathwayBrowser/#/R-XTR-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Xenopus tropicalis 18274 R-BTA-8866601 https://reactome.org/PathwayBrowser/#/R-BTA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Bos taurus 18274 R-CEL-8866601 https://reactome.org/PathwayBrowser/#/R-CEL-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Caenorhabditis elegans 18274 R-CFA-8866601 https://reactome.org/PathwayBrowser/#/R-CFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Canis familiaris 18274 R-DDI-8866601 https://reactome.org/PathwayBrowser/#/R-DDI-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Dictyostelium discoideum 18274 R-DME-8866601 https://reactome.org/PathwayBrowser/#/R-DME-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Drosophila melanogaster 18274 R-DRE-8866601 https://reactome.org/PathwayBrowser/#/R-DRE-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Danio rerio 18274 R-GGA-8866601 https://reactome.org/PathwayBrowser/#/R-GGA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Gallus gallus 18274 R-HSA-8866601 https://reactome.org/PathwayBrowser/#/R-HSA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate TAS Homo sapiens 18274 R-MMU-8866601 https://reactome.org/PathwayBrowser/#/R-MMU-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Mus musculus 18274 R-PFA-8866601 https://reactome.org/PathwayBrowser/#/R-PFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Plasmodium falciparum 18274 R-RNO-8866601 https://reactome.org/PathwayBrowser/#/R-RNO-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Rattus norvegicus 18274 R-SSC-8866601 https://reactome.org/PathwayBrowser/#/R-SSC-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Sus scrofa 18274 R-XTR-8866601 https://reactome.org/PathwayBrowser/#/R-XTR-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Xenopus tropicalis 18276 R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 18276 R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 18276 R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 18276 R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 18276 R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 18276 R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 18276 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 18276 R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 18276 R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 18276 R-RNO-76397 https://reactome.org/PathwayBrowser/#/R-RNO-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Rattus norvegicus 18276 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa 18276 R-XTR-76397 https://reactome.org/PathwayBrowser/#/R-XTR-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Xenopus tropicalis 18278 R-BTA-446191 https://reactome.org/PathwayBrowser/#/R-BTA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Bos taurus 18278 R-BTA-446207 https://reactome.org/PathwayBrowser/#/R-BTA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Bos taurus 18278 R-CEL-446191 https://reactome.org/PathwayBrowser/#/R-CEL-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Caenorhabditis elegans 18278 R-CEL-446207 https://reactome.org/PathwayBrowser/#/R-CEL-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Caenorhabditis elegans 18278 R-CFA-446191 https://reactome.org/PathwayBrowser/#/R-CFA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Canis familiaris 18278 R-CFA-446207 https://reactome.org/PathwayBrowser/#/R-CFA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Canis familiaris 18278 R-DDI-446191 https://reactome.org/PathwayBrowser/#/R-DDI-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Dictyostelium discoideum 18278 R-DME-446191 https://reactome.org/PathwayBrowser/#/R-DME-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Drosophila melanogaster 18278 R-DME-446207 https://reactome.org/PathwayBrowser/#/R-DME-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Drosophila melanogaster 18278 R-DRE-446191 https://reactome.org/PathwayBrowser/#/R-DRE-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Danio rerio 18278 R-GGA-446191 https://reactome.org/PathwayBrowser/#/R-GGA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Gallus gallus 18278 R-GGA-446207 https://reactome.org/PathwayBrowser/#/R-GGA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Gallus gallus 18278 R-HSA-446191 https://reactome.org/PathwayBrowser/#/R-HSA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate TAS Homo sapiens 18278 R-HSA-446207 https://reactome.org/PathwayBrowser/#/R-HSA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP TAS Homo sapiens 18278 R-HSA-5633241 https://reactome.org/PathwayBrowser/#/R-HSA-5633241 Defective ALG14 does not transfer GlcNAc from UDP-GlcNAc to GlcNAcDOLP TAS Homo sapiens 18278 R-MMU-446191 https://reactome.org/PathwayBrowser/#/R-MMU-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Mus musculus 18278 R-MMU-446207 https://reactome.org/PathwayBrowser/#/R-MMU-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Mus musculus 18278 R-PFA-446191 https://reactome.org/PathwayBrowser/#/R-PFA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Plasmodium falciparum 18278 R-PFA-446207 https://reactome.org/PathwayBrowser/#/R-PFA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Plasmodium falciparum 18278 R-RNO-446191 https://reactome.org/PathwayBrowser/#/R-RNO-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Rattus norvegicus 18278 R-RNO-446207 https://reactome.org/PathwayBrowser/#/R-RNO-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Rattus norvegicus 18278 R-SCE-446191 https://reactome.org/PathwayBrowser/#/R-SCE-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Saccharomyces cerevisiae 18278 R-SPO-446191 https://reactome.org/PathwayBrowser/#/R-SPO-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Schizosaccharomyces pombe 18278 R-SPO-446207 https://reactome.org/PathwayBrowser/#/R-SPO-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Schizosaccharomyces pombe 18278 R-SSC-446191 https://reactome.org/PathwayBrowser/#/R-SSC-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Sus scrofa 18278 R-SSC-446207 https://reactome.org/PathwayBrowser/#/R-SSC-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Sus scrofa 18278 R-XTR-446191 https://reactome.org/PathwayBrowser/#/R-XTR-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Xenopus tropicalis 18278 R-XTR-446207 https://reactome.org/PathwayBrowser/#/R-XTR-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Xenopus tropicalis 18283 R-MTU-868608 https://reactome.org/PathwayBrowser/#/R-MTU-868608 Trehalose-6-phosphate is hydrolyzed to trehalose TAS Mycobacterium tuberculosis 18283 R-MTU-868622 https://reactome.org/PathwayBrowser/#/R-MTU-868622 Glucose is transferred from UDP-glucose onto glucose-6-phosphate TAS Mycobacterium tuberculosis 18293 R-HSA-9713837 https://reactome.org/PathwayBrowser/#/R-HSA-9713837 Psoralens in combination with UV generate DNA interstrand crosslinks TAS Homo sapiens 182969 R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 182969 R-BTA-9758682 https://reactome.org/PathwayBrowser/#/R-BTA-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Bos taurus 182969 R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 182969 R-CEL-9758682 https://reactome.org/PathwayBrowser/#/R-CEL-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Caenorhabditis elegans 182969 R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 182969 R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 182969 R-DDI-9758682 https://reactome.org/PathwayBrowser/#/R-DDI-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Dictyostelium discoideum 182969 R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 182969 R-DME-9758682 https://reactome.org/PathwayBrowser/#/R-DME-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Drosophila melanogaster 182969 R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 182969 R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 182969 R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 182969 R-HSA-9758682 https://reactome.org/PathwayBrowser/#/R-HSA-9758682 AKR1C1 hydrogenates PREDN,PREDL TAS Homo sapiens 182969 R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 182969 R-MMU-9758682 https://reactome.org/PathwayBrowser/#/R-MMU-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Mus musculus 182969 R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 182969 R-RNO-9758682 https://reactome.org/PathwayBrowser/#/R-RNO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Rattus norvegicus 182969 R-SCE-9758682 https://reactome.org/PathwayBrowser/#/R-SCE-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Saccharomyces cerevisiae 182969 R-SPO-9758682 https://reactome.org/PathwayBrowser/#/R-SPO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Schizosaccharomyces pombe 182969 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 182969 R-SSC-9758682 https://reactome.org/PathwayBrowser/#/R-SSC-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Sus scrofa 182969 R-XTR-9758682 https://reactome.org/PathwayBrowser/#/R-XTR-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Xenopus tropicalis 18297 R-BTA-1855154 https://reactome.org/PathwayBrowser/#/R-BTA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 18297 R-CEL-1855154 https://reactome.org/PathwayBrowser/#/R-CEL-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 18297 R-CFA-1855154 https://reactome.org/PathwayBrowser/#/R-CFA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 18297 R-DDI-1855154 https://reactome.org/PathwayBrowser/#/R-DDI-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 18297 R-DME-1855154 https://reactome.org/PathwayBrowser/#/R-DME-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 18297 R-DRE-1855154 https://reactome.org/PathwayBrowser/#/R-DRE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 18297 R-GGA-1855154 https://reactome.org/PathwayBrowser/#/R-GGA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 18297 R-HSA-1855154 https://reactome.org/PathwayBrowser/#/R-HSA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 18297 R-HSA-6809561 https://reactome.org/PathwayBrowser/#/R-HSA-6809561 I(1,3)P2 is dephosphorylated into I1P by MTMR7 IEA Homo sapiens 18297 R-HSA-6809565 https://reactome.org/PathwayBrowser/#/R-HSA-6809565 I(1,3)P2 is dephosphorylated into I1P by MTMR7:MTMR9 IEA Homo sapiens 18297 R-MMU-1855154 https://reactome.org/PathwayBrowser/#/R-MMU-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 18297 R-MMU-6809624 https://reactome.org/PathwayBrowser/#/R-MMU-6809624 I(1,3)P2 is dephosphorylated into I1P by Mtmr7 TAS Mus musculus 18297 R-MMU-6809627 https://reactome.org/PathwayBrowser/#/R-MMU-6809627 I(1,3)P2 is dephosphorylated into I1P by Mtmr7:Mtmr9 TAS Mus musculus 18297 R-MTU-879298 https://reactome.org/PathwayBrowser/#/R-MTU-879298 acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate TAS Mycobacterium tuberculosis 18297 R-MTU-879331 https://reactome.org/PathwayBrowser/#/R-MTU-879331 glucose-6-phosphate is converted to inositol-1-phosphate TAS Mycobacterium tuberculosis 18297 R-RNO-1855154 https://reactome.org/PathwayBrowser/#/R-RNO-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 18297 R-SCE-1855154 https://reactome.org/PathwayBrowser/#/R-SCE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 18297 R-SSC-1855154 https://reactome.org/PathwayBrowser/#/R-SSC-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 18297 R-XTR-1855154 https://reactome.org/PathwayBrowser/#/R-XTR-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 182970 R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 182970 R-BTA-9758682 https://reactome.org/PathwayBrowser/#/R-BTA-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Bos taurus 182970 R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 182970 R-CEL-9758682 https://reactome.org/PathwayBrowser/#/R-CEL-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Caenorhabditis elegans 182970 R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 182970 R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 182970 R-DDI-9758682 https://reactome.org/PathwayBrowser/#/R-DDI-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Dictyostelium discoideum 182970 R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 182970 R-DME-9758682 https://reactome.org/PathwayBrowser/#/R-DME-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Drosophila melanogaster 182970 R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 182970 R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 182970 R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 182970 R-HSA-9758682 https://reactome.org/PathwayBrowser/#/R-HSA-9758682 AKR1C1 hydrogenates PREDN,PREDL TAS Homo sapiens 182970 R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 182970 R-MMU-9758682 https://reactome.org/PathwayBrowser/#/R-MMU-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Mus musculus 182970 R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 182970 R-RNO-9758682 https://reactome.org/PathwayBrowser/#/R-RNO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Rattus norvegicus 182970 R-SCE-9758682 https://reactome.org/PathwayBrowser/#/R-SCE-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Saccharomyces cerevisiae 182970 R-SPO-9758682 https://reactome.org/PathwayBrowser/#/R-SPO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Schizosaccharomyces pombe 182970 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 182970 R-SSC-9758682 https://reactome.org/PathwayBrowser/#/R-SSC-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Sus scrofa 182970 R-XTR-9758682 https://reactome.org/PathwayBrowser/#/R-XTR-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Xenopus tropicalis 18304 R-BTA-197235 https://reactome.org/PathwayBrowser/#/R-BTA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 18304 R-BTA-197271 https://reactome.org/PathwayBrowser/#/R-BTA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Bos taurus 18304 R-BTA-200474 https://reactome.org/PathwayBrowser/#/R-BTA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 18304 R-BTA-200512 https://reactome.org/PathwayBrowser/#/R-BTA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 18304 R-CEL-197235 https://reactome.org/PathwayBrowser/#/R-CEL-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 18304 R-CEL-197271 https://reactome.org/PathwayBrowser/#/R-CEL-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Caenorhabditis elegans 18304 R-CEL-200474 https://reactome.org/PathwayBrowser/#/R-CEL-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 18304 R-CEL-200512 https://reactome.org/PathwayBrowser/#/R-CEL-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 18304 R-CFA-197235 https://reactome.org/PathwayBrowser/#/R-CFA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 18304 R-CFA-197271 https://reactome.org/PathwayBrowser/#/R-CFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Canis familiaris 18304 R-CFA-200474 https://reactome.org/PathwayBrowser/#/R-CFA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 18304 R-CFA-200512 https://reactome.org/PathwayBrowser/#/R-CFA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 18304 R-DDI-197235 https://reactome.org/PathwayBrowser/#/R-DDI-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 18304 R-DDI-197271 https://reactome.org/PathwayBrowser/#/R-DDI-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Dictyostelium discoideum 18304 R-DDI-200474 https://reactome.org/PathwayBrowser/#/R-DDI-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 18304 R-DDI-200512 https://reactome.org/PathwayBrowser/#/R-DDI-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 18304 R-DME-197235 https://reactome.org/PathwayBrowser/#/R-DME-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 18304 R-DME-197271 https://reactome.org/PathwayBrowser/#/R-DME-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Drosophila melanogaster 18304 R-DME-200474 https://reactome.org/PathwayBrowser/#/R-DME-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 18304 R-DME-200512 https://reactome.org/PathwayBrowser/#/R-DME-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 18304 R-DRE-197235 https://reactome.org/PathwayBrowser/#/R-DRE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 18304 R-DRE-197271 https://reactome.org/PathwayBrowser/#/R-DRE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Danio rerio 18304 R-DRE-200512 https://reactome.org/PathwayBrowser/#/R-DRE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 18304 R-GGA-197235 https://reactome.org/PathwayBrowser/#/R-GGA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 18304 R-GGA-197271 https://reactome.org/PathwayBrowser/#/R-GGA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Gallus gallus 18304 R-GGA-200474 https://reactome.org/PathwayBrowser/#/R-GGA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 18304 R-GGA-200512 https://reactome.org/PathwayBrowser/#/R-GGA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 18304 R-HSA-197235 https://reactome.org/PathwayBrowser/#/R-HSA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 18304 R-HSA-197271 https://reactome.org/PathwayBrowser/#/R-HSA-197271 NADSYN1 hexamer amidates NAAD to NAD+ TAS Homo sapiens 18304 R-HSA-200474 https://reactome.org/PathwayBrowser/#/R-HSA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 18304 R-HSA-200512 https://reactome.org/PathwayBrowser/#/R-HSA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 18304 R-MMU-197235 https://reactome.org/PathwayBrowser/#/R-MMU-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 18304 R-MMU-197271 https://reactome.org/PathwayBrowser/#/R-MMU-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Mus musculus 18304 R-MMU-200474 https://reactome.org/PathwayBrowser/#/R-MMU-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 18304 R-MMU-200512 https://reactome.org/PathwayBrowser/#/R-MMU-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 18304 R-PFA-197271 https://reactome.org/PathwayBrowser/#/R-PFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Plasmodium falciparum 18304 R-RNO-197235 https://reactome.org/PathwayBrowser/#/R-RNO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 18304 R-RNO-197271 https://reactome.org/PathwayBrowser/#/R-RNO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Rattus norvegicus 18304 R-RNO-200474 https://reactome.org/PathwayBrowser/#/R-RNO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 18304 R-RNO-200512 https://reactome.org/PathwayBrowser/#/R-RNO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 18304 R-SCE-197235 https://reactome.org/PathwayBrowser/#/R-SCE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 18304 R-SCE-197271 https://reactome.org/PathwayBrowser/#/R-SCE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Saccharomyces cerevisiae 18304 R-SCE-200474 https://reactome.org/PathwayBrowser/#/R-SCE-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 18304 R-SCE-200512 https://reactome.org/PathwayBrowser/#/R-SCE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 18304 R-SPO-197235 https://reactome.org/PathwayBrowser/#/R-SPO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 18304 R-SPO-197271 https://reactome.org/PathwayBrowser/#/R-SPO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Schizosaccharomyces pombe 18304 R-SPO-200474 https://reactome.org/PathwayBrowser/#/R-SPO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 18304 R-SPO-200512 https://reactome.org/PathwayBrowser/#/R-SPO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 18304 R-SSC-197235 https://reactome.org/PathwayBrowser/#/R-SSC-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 18304 R-SSC-197271 https://reactome.org/PathwayBrowser/#/R-SSC-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Sus scrofa 18304 R-SSC-200474 https://reactome.org/PathwayBrowser/#/R-SSC-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 18304 R-SSC-200512 https://reactome.org/PathwayBrowser/#/R-SSC-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 18305 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 18305 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 18305 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 18305 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 18305 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 18305 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 18305 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 18305 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 18305 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 18305 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 18305 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 18305 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 18305 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 18305 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 18305 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 18305 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 18305 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 18305 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 18305 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 18305 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 18305 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 18305 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 18305 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 18305 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 18305 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 18305 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 18305 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 18305 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 18305 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 18305 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 18305 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 18305 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 18305 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 18305 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 18305 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 18305 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 18305 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 18305 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 18305 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 18305 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 18305 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 18305 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 18313 R-BTA-9846477 https://reactome.org/PathwayBrowser/#/R-BTA-9846477 A4GALT transfers galactose to LacCer IEA Bos taurus 18313 R-CFA-8878914 https://reactome.org/PathwayBrowser/#/R-CFA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Canis familiaris 18313 R-CFA-9846477 https://reactome.org/PathwayBrowser/#/R-CFA-9846477 A4GALT transfers galactose to LacCer IEA Canis familiaris 18313 R-DME-8878914 https://reactome.org/PathwayBrowser/#/R-DME-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Drosophila melanogaster 18313 R-DME-9846477 https://reactome.org/PathwayBrowser/#/R-DME-9846477 A4GALT transfers galactose to LacCer IEA Drosophila melanogaster 18313 R-GGA-8878914 https://reactome.org/PathwayBrowser/#/R-GGA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Gallus gallus 18313 R-GGA-9846477 https://reactome.org/PathwayBrowser/#/R-GGA-9846477 A4GALT transfers galactose to LacCer IEA Gallus gallus 18313 R-HSA-8878914 https://reactome.org/PathwayBrowser/#/R-HSA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer TAS Homo sapiens 18313 R-HSA-9846477 https://reactome.org/PathwayBrowser/#/R-HSA-9846477 A4GALT transfers galactose to LacCer TAS Homo sapiens 18313 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 18313 R-MMU-8878914 https://reactome.org/PathwayBrowser/#/R-MMU-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Mus musculus 18313 R-MMU-9846477 https://reactome.org/PathwayBrowser/#/R-MMU-9846477 A4GALT transfers galactose to LacCer IEA Mus musculus 18313 R-RNO-8878914 https://reactome.org/PathwayBrowser/#/R-RNO-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Rattus norvegicus 18313 R-RNO-9846477 https://reactome.org/PathwayBrowser/#/R-RNO-9846477 A4GALT transfers galactose to LacCer IEA Rattus norvegicus 18313 R-SSC-8878914 https://reactome.org/PathwayBrowser/#/R-SSC-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Sus scrofa 18313 R-SSC-9846477 https://reactome.org/PathwayBrowser/#/R-SSC-9846477 A4GALT transfers galactose to LacCer IEA Sus scrofa 18315 R-BTA-209891 https://reactome.org/PathwayBrowser/#/R-BTA-209891 Dopamine is oxidised to noradrenaline IEA Bos taurus 18315 R-CFA-209891 https://reactome.org/PathwayBrowser/#/R-CFA-209891 Dopamine is oxidised to noradrenaline IEA Canis familiaris 18315 R-DME-209891 https://reactome.org/PathwayBrowser/#/R-DME-209891 Dopamine is oxidised to noradrenaline IEA Drosophila melanogaster 18315 R-DRE-209891 https://reactome.org/PathwayBrowser/#/R-DRE-209891 Dopamine is oxidised to noradrenaline IEA Danio rerio 18315 R-GGA-209891 https://reactome.org/PathwayBrowser/#/R-GGA-209891 Dopamine is oxidised to noradrenaline IEA Gallus gallus 18315 R-HSA-209891 https://reactome.org/PathwayBrowser/#/R-HSA-209891 Dopamine is oxidised to noradrenaline TAS Homo sapiens 18315 R-MMU-209891 https://reactome.org/PathwayBrowser/#/R-MMU-209891 Dopamine is oxidised to noradrenaline IEA Mus musculus 18315 R-RNO-209891 https://reactome.org/PathwayBrowser/#/R-RNO-209891 Dopamine is oxidised to noradrenaline IEA Rattus norvegicus 18315 R-SSC-209891 https://reactome.org/PathwayBrowser/#/R-SSC-209891 Dopamine is oxidised to noradrenaline IEA Sus scrofa 18315 R-XTR-209891 https://reactome.org/PathwayBrowser/#/R-XTR-209891 Dopamine is oxidised to noradrenaline IEA Xenopus tropicalis 18327 R-BTA-70906 https://reactome.org/PathwayBrowser/#/R-BTA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Bos taurus 18327 R-BTA-70920 https://reactome.org/PathwayBrowser/#/R-BTA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Bos taurus 18327 R-CEL-70906 https://reactome.org/PathwayBrowser/#/R-CEL-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Caenorhabditis elegans 18327 R-CFA-70906 https://reactome.org/PathwayBrowser/#/R-CFA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Canis familiaris 18327 R-CFA-70920 https://reactome.org/PathwayBrowser/#/R-CFA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Canis familiaris 18327 R-DDI-70906 https://reactome.org/PathwayBrowser/#/R-DDI-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Dictyostelium discoideum 18327 R-DDI-70920 https://reactome.org/PathwayBrowser/#/R-DDI-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Dictyostelium discoideum 18327 R-DRE-70906 https://reactome.org/PathwayBrowser/#/R-DRE-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Danio rerio 18327 R-GGA-70906 https://reactome.org/PathwayBrowser/#/R-GGA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Gallus gallus 18327 R-GGA-70920 https://reactome.org/PathwayBrowser/#/R-GGA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Gallus gallus 18327 R-HSA-70906 https://reactome.org/PathwayBrowser/#/R-HSA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ TAS Homo sapiens 18327 R-HSA-70920 https://reactome.org/PathwayBrowser/#/R-HSA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate TAS Homo sapiens 18327 R-MMU-70906 https://reactome.org/PathwayBrowser/#/R-MMU-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Mus musculus 18327 R-MMU-70920 https://reactome.org/PathwayBrowser/#/R-MMU-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Mus musculus 18327 R-RNO-70906 https://reactome.org/PathwayBrowser/#/R-RNO-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Rattus norvegicus 18327 R-RNO-70920 https://reactome.org/PathwayBrowser/#/R-RNO-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Rattus norvegicus 18327 R-SSC-70906 https://reactome.org/PathwayBrowser/#/R-SSC-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Sus scrofa 18327 R-SSC-70920 https://reactome.org/PathwayBrowser/#/R-SSC-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Sus scrofa 18327 R-XTR-70906 https://reactome.org/PathwayBrowser/#/R-XTR-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Xenopus tropicalis 18327 R-XTR-70920 https://reactome.org/PathwayBrowser/#/R-XTR-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Xenopus tropicalis 18332 R-BTA-209772 https://reactome.org/PathwayBrowser/#/R-BTA-209772 Thyroxine is deiodinated to triiodothyronine IEA Bos taurus 18332 R-BTA-209840 https://reactome.org/PathwayBrowser/#/R-BTA-209840 Two DITs combine to form thyroxine IEA Bos taurus 18332 R-BTA-350869 https://reactome.org/PathwayBrowser/#/R-BTA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Bos taurus 18332 R-BTA-879575 https://reactome.org/PathwayBrowser/#/R-BTA-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Bos taurus 18332 R-BTA-879584 https://reactome.org/PathwayBrowser/#/R-BTA-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Bos taurus 18332 R-BTA-9631987 https://reactome.org/PathwayBrowser/#/R-BTA-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Bos taurus 18332 R-CEL-209840 https://reactome.org/PathwayBrowser/#/R-CEL-209840 Two DITs combine to form thyroxine IEA Caenorhabditis elegans 18332 R-CEL-879575 https://reactome.org/PathwayBrowser/#/R-CEL-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Caenorhabditis elegans 18332 R-CEL-9631987 https://reactome.org/PathwayBrowser/#/R-CEL-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Caenorhabditis elegans 18332 R-CFA-209772 https://reactome.org/PathwayBrowser/#/R-CFA-209772 Thyroxine is deiodinated to triiodothyronine IEA Canis familiaris 18332 R-CFA-209840 https://reactome.org/PathwayBrowser/#/R-CFA-209840 Two DITs combine to form thyroxine IEA Canis familiaris 18332 R-CFA-879575 https://reactome.org/PathwayBrowser/#/R-CFA-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Canis familiaris 18332 R-CFA-879584 https://reactome.org/PathwayBrowser/#/R-CFA-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Canis familiaris 18332 R-CFA-9631987 https://reactome.org/PathwayBrowser/#/R-CFA-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Canis familiaris 18332 R-DDI-209772 https://reactome.org/PathwayBrowser/#/R-DDI-209772 Thyroxine is deiodinated to triiodothyronine IEA Dictyostelium discoideum 18332 R-DDI-209840 https://reactome.org/PathwayBrowser/#/R-DDI-209840 Two DITs combine to form thyroxine IEA Dictyostelium discoideum 18332 R-DDI-350869 https://reactome.org/PathwayBrowser/#/R-DDI-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Dictyostelium discoideum 18332 R-DDI-879575 https://reactome.org/PathwayBrowser/#/R-DDI-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Dictyostelium discoideum 18332 R-DME-209840 https://reactome.org/PathwayBrowser/#/R-DME-209840 Two DITs combine to form thyroxine IEA Drosophila melanogaster 18332 R-DME-879575 https://reactome.org/PathwayBrowser/#/R-DME-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Drosophila melanogaster 18332 R-DME-9631987 https://reactome.org/PathwayBrowser/#/R-DME-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Drosophila melanogaster 18332 R-DRE-879575 https://reactome.org/PathwayBrowser/#/R-DRE-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Danio rerio 18332 R-DRE-9631987 https://reactome.org/PathwayBrowser/#/R-DRE-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Danio rerio 18332 R-GGA-209772 https://reactome.org/PathwayBrowser/#/R-GGA-209772 Thyroxine is deiodinated to triiodothyronine IEA Gallus gallus 18332 R-GGA-209840 https://reactome.org/PathwayBrowser/#/R-GGA-209840 Two DITs combine to form thyroxine IEA Gallus gallus 18332 R-GGA-879575 https://reactome.org/PathwayBrowser/#/R-GGA-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Gallus gallus 18332 R-GGA-879584 https://reactome.org/PathwayBrowser/#/R-GGA-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Gallus gallus 18332 R-GGA-9631987 https://reactome.org/PathwayBrowser/#/R-GGA-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Gallus gallus 18332 R-HSA-209772 https://reactome.org/PathwayBrowser/#/R-HSA-209772 Thyroxine is deiodinated to triiodothyronine TAS Homo sapiens 18332 R-HSA-209840 https://reactome.org/PathwayBrowser/#/R-HSA-209840 Two DITs combine to form thyroxine TAS Homo sapiens 18332 R-HSA-350869 https://reactome.org/PathwayBrowser/#/R-HSA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) TAS Homo sapiens 18332 R-HSA-879575 https://reactome.org/PathwayBrowser/#/R-HSA-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol TAS Homo sapiens 18332 R-HSA-879584 https://reactome.org/PathwayBrowser/#/R-HSA-879584 SLCO3A1 isoform 1 has abroad substrate specificity TAS Homo sapiens 18332 R-HSA-9631987 https://reactome.org/PathwayBrowser/#/R-HSA-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol TAS Homo sapiens 18332 R-MMU-209772 https://reactome.org/PathwayBrowser/#/R-MMU-209772 Thyroxine is deiodinated to triiodothyronine IEA Mus musculus 18332 R-MMU-209840 https://reactome.org/PathwayBrowser/#/R-MMU-209840 Two DITs combine to form thyroxine IEA Mus musculus 18332 R-MMU-350869 https://reactome.org/PathwayBrowser/#/R-MMU-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Mus musculus 18332 R-MMU-879575 https://reactome.org/PathwayBrowser/#/R-MMU-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Mus musculus 18332 R-MMU-879584 https://reactome.org/PathwayBrowser/#/R-MMU-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Mus musculus 18332 R-MMU-9631987 https://reactome.org/PathwayBrowser/#/R-MMU-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Mus musculus 18332 R-PFA-879575 https://reactome.org/PathwayBrowser/#/R-PFA-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Plasmodium falciparum 18332 R-RNO-209772 https://reactome.org/PathwayBrowser/#/R-RNO-209772 Thyroxine is deiodinated to triiodothyronine IEA Rattus norvegicus 18332 R-RNO-209840 https://reactome.org/PathwayBrowser/#/R-RNO-209840 Two DITs combine to form thyroxine IEA Rattus norvegicus 18332 R-RNO-350869 https://reactome.org/PathwayBrowser/#/R-RNO-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Rattus norvegicus 18332 R-RNO-879575 https://reactome.org/PathwayBrowser/#/R-RNO-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Rattus norvegicus 18332 R-RNO-879584 https://reactome.org/PathwayBrowser/#/R-RNO-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Rattus norvegicus 18332 R-RNO-9631987 https://reactome.org/PathwayBrowser/#/R-RNO-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Rattus norvegicus 18332 R-SCE-879575 https://reactome.org/PathwayBrowser/#/R-SCE-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Saccharomyces cerevisiae 18332 R-SSC-209772 https://reactome.org/PathwayBrowser/#/R-SSC-209772 Thyroxine is deiodinated to triiodothyronine IEA Sus scrofa 18332 R-SSC-209840 https://reactome.org/PathwayBrowser/#/R-SSC-209840 Two DITs combine to form thyroxine IEA Sus scrofa 18332 R-SSC-350869 https://reactome.org/PathwayBrowser/#/R-SSC-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Sus scrofa 18332 R-SSC-879575 https://reactome.org/PathwayBrowser/#/R-SSC-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Sus scrofa 18332 R-SSC-879584 https://reactome.org/PathwayBrowser/#/R-SSC-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Sus scrofa 18332 R-SSC-9631987 https://reactome.org/PathwayBrowser/#/R-SSC-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Sus scrofa 18332 R-XTR-879575 https://reactome.org/PathwayBrowser/#/R-XTR-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Xenopus tropicalis 18332 R-XTR-9631987 https://reactome.org/PathwayBrowser/#/R-XTR-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Xenopus tropicalis 18335 R-BTA-964958 https://reactome.org/PathwayBrowser/#/R-BTA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Bos taurus 18335 R-BTA-965079 https://reactome.org/PathwayBrowser/#/R-BTA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Bos taurus 18335 R-CEL-964958 https://reactome.org/PathwayBrowser/#/R-CEL-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Caenorhabditis elegans 18335 R-CEL-965079 https://reactome.org/PathwayBrowser/#/R-CEL-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Caenorhabditis elegans 18335 R-CFA-964958 https://reactome.org/PathwayBrowser/#/R-CFA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Canis familiaris 18335 R-CFA-965079 https://reactome.org/PathwayBrowser/#/R-CFA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Canis familiaris 18335 R-DDI-964958 https://reactome.org/PathwayBrowser/#/R-DDI-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Dictyostelium discoideum 18335 R-DDI-965079 https://reactome.org/PathwayBrowser/#/R-DDI-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Dictyostelium discoideum 18335 R-DME-964958 https://reactome.org/PathwayBrowser/#/R-DME-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Drosophila melanogaster 18335 R-DME-965079 https://reactome.org/PathwayBrowser/#/R-DME-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Drosophila melanogaster 18335 R-DRE-964958 https://reactome.org/PathwayBrowser/#/R-DRE-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Danio rerio 18335 R-GGA-964958 https://reactome.org/PathwayBrowser/#/R-GGA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Gallus gallus 18335 R-GGA-965079 https://reactome.org/PathwayBrowser/#/R-GGA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Gallus gallus 18335 R-HSA-964958 https://reactome.org/PathwayBrowser/#/R-HSA-964958 2xPDXK:2xZn2+ phosphorylates PXA TAS Homo sapiens 18335 R-HSA-965079 https://reactome.org/PathwayBrowser/#/R-HSA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP TAS Homo sapiens 18335 R-MMU-964958 https://reactome.org/PathwayBrowser/#/R-MMU-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Mus musculus 18335 R-MMU-965079 https://reactome.org/PathwayBrowser/#/R-MMU-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Mus musculus 18335 R-PFA-964958 https://reactome.org/PathwayBrowser/#/R-PFA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Plasmodium falciparum 18335 R-RNO-964958 https://reactome.org/PathwayBrowser/#/R-RNO-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Rattus norvegicus 18335 R-RNO-965079 https://reactome.org/PathwayBrowser/#/R-RNO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Rattus norvegicus 18335 R-SCE-964958 https://reactome.org/PathwayBrowser/#/R-SCE-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Saccharomyces cerevisiae 18335 R-SCE-965079 https://reactome.org/PathwayBrowser/#/R-SCE-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Saccharomyces cerevisiae 18335 R-SPO-964958 https://reactome.org/PathwayBrowser/#/R-SPO-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Schizosaccharomyces pombe 18335 R-SPO-965079 https://reactome.org/PathwayBrowser/#/R-SPO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Schizosaccharomyces pombe 18335 R-SSC-964958 https://reactome.org/PathwayBrowser/#/R-SSC-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Sus scrofa 18335 R-SSC-965079 https://reactome.org/PathwayBrowser/#/R-SSC-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Sus scrofa 18335 R-XTR-964958 https://reactome.org/PathwayBrowser/#/R-XTR-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Xenopus tropicalis 18335 R-XTR-965079 https://reactome.org/PathwayBrowser/#/R-XTR-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Xenopus tropicalis 18341 R-BTA-446207 https://reactome.org/PathwayBrowser/#/R-BTA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Bos taurus 18341 R-BTA-446218 https://reactome.org/PathwayBrowser/#/R-BTA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Bos taurus 18341 R-CEL-446207 https://reactome.org/PathwayBrowser/#/R-CEL-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Caenorhabditis elegans 18341 R-CEL-446218 https://reactome.org/PathwayBrowser/#/R-CEL-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Caenorhabditis elegans 18341 R-CFA-446207 https://reactome.org/PathwayBrowser/#/R-CFA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Canis familiaris 18341 R-CFA-446218 https://reactome.org/PathwayBrowser/#/R-CFA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Canis familiaris 18341 R-DDI-446218 https://reactome.org/PathwayBrowser/#/R-DDI-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Dictyostelium discoideum 18341 R-DME-446207 https://reactome.org/PathwayBrowser/#/R-DME-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Drosophila melanogaster 18341 R-DME-446218 https://reactome.org/PathwayBrowser/#/R-DME-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Drosophila melanogaster 18341 R-DRE-446218 https://reactome.org/PathwayBrowser/#/R-DRE-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Danio rerio 18341 R-GGA-446207 https://reactome.org/PathwayBrowser/#/R-GGA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Gallus gallus 18341 R-GGA-446218 https://reactome.org/PathwayBrowser/#/R-GGA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Gallus gallus 18341 R-HSA-446207 https://reactome.org/PathwayBrowser/#/R-HSA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP TAS Homo sapiens 18341 R-HSA-446218 https://reactome.org/PathwayBrowser/#/R-HSA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 TAS Homo sapiens 18341 R-HSA-4549382 https://reactome.org/PathwayBrowser/#/R-HSA-4549382 Defective ALG1 does not transfer the first Man to the N-glycan precursor TAS Homo sapiens 18341 R-MMU-446207 https://reactome.org/PathwayBrowser/#/R-MMU-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Mus musculus 18341 R-MMU-446218 https://reactome.org/PathwayBrowser/#/R-MMU-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Mus musculus 18341 R-PFA-446207 https://reactome.org/PathwayBrowser/#/R-PFA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Plasmodium falciparum 18341 R-RNO-446207 https://reactome.org/PathwayBrowser/#/R-RNO-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Rattus norvegicus 18341 R-RNO-446218 https://reactome.org/PathwayBrowser/#/R-RNO-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Rattus norvegicus 18341 R-SCE-446218 https://reactome.org/PathwayBrowser/#/R-SCE-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Saccharomyces cerevisiae 18341 R-SPO-446207 https://reactome.org/PathwayBrowser/#/R-SPO-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Schizosaccharomyces pombe 18341 R-SPO-446218 https://reactome.org/PathwayBrowser/#/R-SPO-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Schizosaccharomyces pombe 18341 R-SSC-446207 https://reactome.org/PathwayBrowser/#/R-SSC-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Sus scrofa 18341 R-SSC-446218 https://reactome.org/PathwayBrowser/#/R-SSC-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Sus scrofa 18341 R-XTR-446207 https://reactome.org/PathwayBrowser/#/R-XTR-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Xenopus tropicalis 18344 R-BTA-6805205 https://reactome.org/PathwayBrowser/#/R-BTA-6805205 GPR35 binds kynurenic acid IEA Bos taurus 18344 R-CEL-6805205 https://reactome.org/PathwayBrowser/#/R-CEL-6805205 GPR35 binds kynurenic acid IEA Caenorhabditis elegans 18344 R-CFA-6805205 https://reactome.org/PathwayBrowser/#/R-CFA-6805205 GPR35 binds kynurenic acid IEA Canis familiaris 18344 R-DRE-6805205 https://reactome.org/PathwayBrowser/#/R-DRE-6805205 GPR35 binds kynurenic acid IEA Danio rerio 18344 R-GGA-6805205 https://reactome.org/PathwayBrowser/#/R-GGA-6805205 GPR35 binds kynurenic acid IEA Gallus gallus 18344 R-HSA-6805205 https://reactome.org/PathwayBrowser/#/R-HSA-6805205 GPR35 binds kynurenic acid TAS Homo sapiens 18344 R-HSA-893597 https://reactome.org/PathwayBrowser/#/R-HSA-893597 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [mitochondrial] TAS Homo sapiens 18344 R-HSA-893609 https://reactome.org/PathwayBrowser/#/R-HSA-893609 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [cytosolic] TAS Homo sapiens 18344 R-MMU-6805205 https://reactome.org/PathwayBrowser/#/R-MMU-6805205 GPR35 binds kynurenic acid IEA Mus musculus 18344 R-RNO-6805205 https://reactome.org/PathwayBrowser/#/R-RNO-6805205 GPR35 binds kynurenic acid IEA Rattus norvegicus 18344 R-SSC-6805205 https://reactome.org/PathwayBrowser/#/R-SSC-6805205 GPR35 binds kynurenic acid IEA Sus scrofa 18344 R-XTR-6805205 https://reactome.org/PathwayBrowser/#/R-XTR-6805205 GPR35 binds kynurenic acid IEA Xenopus tropicalis 18346 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 18346 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 18346 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 18346 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 18346 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 18346 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 18346 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 18346 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 18346 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 18358 R-HSA-9713837 https://reactome.org/PathwayBrowser/#/R-HSA-9713837 Psoralens in combination with UV generate DNA interstrand crosslinks TAS Homo sapiens 18364 R-BTA-194674 https://reactome.org/PathwayBrowser/#/R-BTA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Bos taurus 18364 R-BTA-194698 https://reactome.org/PathwayBrowser/#/R-BTA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Bos taurus 18364 R-CFA-194674 https://reactome.org/PathwayBrowser/#/R-CFA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Canis familiaris 18364 R-CFA-194698 https://reactome.org/PathwayBrowser/#/R-CFA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Canis familiaris 18364 R-DDI-194674 https://reactome.org/PathwayBrowser/#/R-DDI-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Dictyostelium discoideum 18364 R-DDI-194698 https://reactome.org/PathwayBrowser/#/R-DDI-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Dictyostelium discoideum 18364 R-DME-194698 https://reactome.org/PathwayBrowser/#/R-DME-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Drosophila melanogaster 18364 R-DRE-194674 https://reactome.org/PathwayBrowser/#/R-DRE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Danio rerio 18364 R-DRE-194698 https://reactome.org/PathwayBrowser/#/R-DRE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Danio rerio 18364 R-GGA-194674 https://reactome.org/PathwayBrowser/#/R-GGA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Gallus gallus 18364 R-HSA-194674 https://reactome.org/PathwayBrowser/#/R-HSA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] TAS Homo sapiens 18364 R-HSA-194698 https://reactome.org/PathwayBrowser/#/R-HSA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] TAS Homo sapiens 18364 R-MMU-194674 https://reactome.org/PathwayBrowser/#/R-MMU-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Mus musculus 18364 R-MMU-194698 https://reactome.org/PathwayBrowser/#/R-MMU-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Mus musculus 18364 R-RNO-194674 https://reactome.org/PathwayBrowser/#/R-RNO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Rattus norvegicus 18364 R-RNO-194698 https://reactome.org/PathwayBrowser/#/R-RNO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Rattus norvegicus 18364 R-SCE-194674 https://reactome.org/PathwayBrowser/#/R-SCE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Saccharomyces cerevisiae 18364 R-SCE-194698 https://reactome.org/PathwayBrowser/#/R-SCE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Saccharomyces cerevisiae 18364 R-SPO-194674 https://reactome.org/PathwayBrowser/#/R-SPO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Schizosaccharomyces pombe 18364 R-SPO-194698 https://reactome.org/PathwayBrowser/#/R-SPO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Schizosaccharomyces pombe 18364 R-SSC-194674 https://reactome.org/PathwayBrowser/#/R-SSC-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Sus scrofa 18364 R-SSC-194698 https://reactome.org/PathwayBrowser/#/R-SSC-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Sus scrofa 18364 R-XTR-194674 https://reactome.org/PathwayBrowser/#/R-XTR-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Xenopus tropicalis 18366 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 18366 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 18366 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 18366 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 18366 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 18366 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 18366 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 18366 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 18366 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 18366 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 18366 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 18366 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 18366 R-HSA-379993 https://reactome.org/PathwayBrowser/#/R-HSA-379993 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 18366 R-HSA-380224 https://reactome.org/PathwayBrowser/#/R-HSA-380224 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 18366 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 18366 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 18366 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 18366 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 18366 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 18366 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 18367 R-BTA-5362459 https://reactome.org/PathwayBrowser/#/R-BTA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Bos taurus 18367 R-BTA-9755044 https://reactome.org/PathwayBrowser/#/R-BTA-9755044 PNP trimer transforms RBV to T-CONH2 IEA Bos taurus 18367 R-BTA-9755078 https://reactome.org/PathwayBrowser/#/R-BTA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Bos taurus 18367 R-CEL-9755044 https://reactome.org/PathwayBrowser/#/R-CEL-9755044 PNP trimer transforms RBV to T-CONH2 IEA Caenorhabditis elegans 18367 R-CEL-9755078 https://reactome.org/PathwayBrowser/#/R-CEL-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Caenorhabditis elegans 18367 R-CFA-5362459 https://reactome.org/PathwayBrowser/#/R-CFA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Canis familiaris 18367 R-CFA-9755044 https://reactome.org/PathwayBrowser/#/R-CFA-9755044 PNP trimer transforms RBV to T-CONH2 IEA Canis familiaris 18367 R-CFA-9755078 https://reactome.org/PathwayBrowser/#/R-CFA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Canis familiaris 18367 R-DDI-9755078 https://reactome.org/PathwayBrowser/#/R-DDI-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Dictyostelium discoideum 18367 R-DME-5362459 https://reactome.org/PathwayBrowser/#/R-DME-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Drosophila melanogaster 18367 R-DME-9755044 https://reactome.org/PathwayBrowser/#/R-DME-9755044 PNP trimer transforms RBV to T-CONH2 IEA Drosophila melanogaster 18367 R-DME-9755078 https://reactome.org/PathwayBrowser/#/R-DME-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Drosophila melanogaster 18367 R-DRE-5362459 https://reactome.org/PathwayBrowser/#/R-DRE-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Danio rerio 18367 R-DRE-9755044 https://reactome.org/PathwayBrowser/#/R-DRE-9755044 PNP trimer transforms RBV to T-CONH2 IEA Danio rerio 18367 R-GGA-5362459 https://reactome.org/PathwayBrowser/#/R-GGA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Gallus gallus 18367 R-GGA-9755078 https://reactome.org/PathwayBrowser/#/R-GGA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Gallus gallus 18367 R-HSA-5362459 https://reactome.org/PathwayBrowser/#/R-HSA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol TAS Homo sapiens 18367 R-HSA-5387389 https://reactome.org/PathwayBrowser/#/R-HSA-5387389 Hh processing variants are translocated to the cytosol in a VCP-dependent manner TAS Homo sapiens 18367 R-HSA-9755044 https://reactome.org/PathwayBrowser/#/R-HSA-9755044 PNP trimer transforms RBV to T-CONH2 TAS Homo sapiens 18367 R-HSA-9755078 https://reactome.org/PathwayBrowser/#/R-HSA-9755078 NT5C2 tetramer dephosphorylates RBV-MP TAS Homo sapiens 18367 R-MMU-5362459 https://reactome.org/PathwayBrowser/#/R-MMU-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Mus musculus 18367 R-MMU-9755044 https://reactome.org/PathwayBrowser/#/R-MMU-9755044 PNP trimer transforms RBV to T-CONH2 IEA Mus musculus 18367 R-MMU-9755078 https://reactome.org/PathwayBrowser/#/R-MMU-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Mus musculus 18367 R-RNO-5362459 https://reactome.org/PathwayBrowser/#/R-RNO-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Rattus norvegicus 18367 R-RNO-9755044 https://reactome.org/PathwayBrowser/#/R-RNO-9755044 PNP trimer transforms RBV to T-CONH2 IEA Rattus norvegicus 18367 R-RNO-9755078 https://reactome.org/PathwayBrowser/#/R-RNO-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Rattus norvegicus 18367 R-SCE-9755044 https://reactome.org/PathwayBrowser/#/R-SCE-9755044 PNP trimer transforms RBV to T-CONH2 IEA Saccharomyces cerevisiae 18367 R-SPO-9755044 https://reactome.org/PathwayBrowser/#/R-SPO-9755044 PNP trimer transforms RBV to T-CONH2 IEA Schizosaccharomyces pombe 18367 R-SSC-5362459 https://reactome.org/PathwayBrowser/#/R-SSC-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Sus scrofa 18367 R-SSC-9755044 https://reactome.org/PathwayBrowser/#/R-SSC-9755044 PNP trimer transforms RBV to T-CONH2 IEA Sus scrofa 18367 R-SSC-9755078 https://reactome.org/PathwayBrowser/#/R-SSC-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Sus scrofa 18367 R-XTR-5362459 https://reactome.org/PathwayBrowser/#/R-XTR-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Xenopus tropicalis 18367 R-XTR-9755044 https://reactome.org/PathwayBrowser/#/R-XTR-9755044 PNP trimer transforms RBV to T-CONH2 IEA Xenopus tropicalis 18367 R-XTR-9755078 https://reactome.org/PathwayBrowser/#/R-XTR-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Xenopus tropicalis 18377 R-BTA-198563 https://reactome.org/PathwayBrowser/#/R-BTA-198563 IDO1 dioxygenates L-Trp to NFK IEA Bos taurus 18377 R-BTA-71188 https://reactome.org/PathwayBrowser/#/R-BTA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Bos taurus 18377 R-BTA-888614 https://reactome.org/PathwayBrowser/#/R-BTA-888614 IDO2 dioxygenates L-Trp to NFK IEA Bos taurus 18377 R-CEL-71188 https://reactome.org/PathwayBrowser/#/R-CEL-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Caenorhabditis elegans 18377 R-CFA-198563 https://reactome.org/PathwayBrowser/#/R-CFA-198563 IDO1 dioxygenates L-Trp to NFK IEA Canis familiaris 18377 R-CFA-71188 https://reactome.org/PathwayBrowser/#/R-CFA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Canis familiaris 18377 R-CFA-888614 https://reactome.org/PathwayBrowser/#/R-CFA-888614 IDO2 dioxygenates L-Trp to NFK IEA Canis familiaris 18377 R-DDI-71188 https://reactome.org/PathwayBrowser/#/R-DDI-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Dictyostelium discoideum 18377 R-DME-71188 https://reactome.org/PathwayBrowser/#/R-DME-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Drosophila melanogaster 18377 R-DRE-71188 https://reactome.org/PathwayBrowser/#/R-DRE-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Danio rerio 18377 R-DRE-888614 https://reactome.org/PathwayBrowser/#/R-DRE-888614 IDO2 dioxygenates L-Trp to NFK IEA Danio rerio 18377 R-GGA-71188 https://reactome.org/PathwayBrowser/#/R-GGA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Gallus gallus 18377 R-GGA-888614 https://reactome.org/PathwayBrowser/#/R-GGA-888614 IDO2 dioxygenates L-Trp to NFK IEA Gallus gallus 18377 R-HSA-198563 https://reactome.org/PathwayBrowser/#/R-HSA-198563 IDO1 dioxygenates L-Trp to NFK TAS Homo sapiens 18377 R-HSA-71188 https://reactome.org/PathwayBrowser/#/R-HSA-71188 TDO tetramer dioxygenates L-Trp to NFK TAS Homo sapiens 18377 R-HSA-71189 https://reactome.org/PathwayBrowser/#/R-HSA-71189 AFMID hydrolyses NFK to L-KYN IEA Homo sapiens 18377 R-HSA-888614 https://reactome.org/PathwayBrowser/#/R-HSA-888614 IDO2 dioxygenates L-Trp to NFK TAS Homo sapiens 18377 R-MMU-198563 https://reactome.org/PathwayBrowser/#/R-MMU-198563 IDO1 dioxygenates L-Trp to NFK IEA Mus musculus 18377 R-MMU-71188 https://reactome.org/PathwayBrowser/#/R-MMU-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Mus musculus 18377 R-MMU-71196 https://reactome.org/PathwayBrowser/#/R-MMU-71196 N-formylkynurenine + H2O => kynurenine + formate [mouse] TAS Mus musculus 18377 R-MMU-888614 https://reactome.org/PathwayBrowser/#/R-MMU-888614 IDO2 dioxygenates L-Trp to NFK IEA Mus musculus 18377 R-RNO-198563 https://reactome.org/PathwayBrowser/#/R-RNO-198563 IDO1 dioxygenates L-Trp to NFK IEA Rattus norvegicus 18377 R-RNO-71188 https://reactome.org/PathwayBrowser/#/R-RNO-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Rattus norvegicus 18377 R-RNO-888614 https://reactome.org/PathwayBrowser/#/R-RNO-888614 IDO2 dioxygenates L-Trp to NFK IEA Rattus norvegicus 18377 R-SCE-198563 https://reactome.org/PathwayBrowser/#/R-SCE-198563 IDO1 dioxygenates L-Trp to NFK IEA Saccharomyces cerevisiae 18377 R-SCE-888614 https://reactome.org/PathwayBrowser/#/R-SCE-888614 IDO2 dioxygenates L-Trp to NFK IEA Saccharomyces cerevisiae 18377 R-SSC-198563 https://reactome.org/PathwayBrowser/#/R-SSC-198563 IDO1 dioxygenates L-Trp to NFK IEA Sus scrofa 18377 R-SSC-71188 https://reactome.org/PathwayBrowser/#/R-SSC-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Sus scrofa 18377 R-SSC-888614 https://reactome.org/PathwayBrowser/#/R-SSC-888614 IDO2 dioxygenates L-Trp to NFK IEA Sus scrofa 18377 R-XTR-71188 https://reactome.org/PathwayBrowser/#/R-XTR-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Xenopus tropicalis 18377 R-XTR-888614 https://reactome.org/PathwayBrowser/#/R-XTR-888614 IDO2 dioxygenates L-Trp to NFK IEA Xenopus tropicalis 18384 R-BTA-1855208 https://reactome.org/PathwayBrowser/#/R-BTA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Bos taurus 18384 R-BTA-1855211 https://reactome.org/PathwayBrowser/#/R-BTA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 18384 R-CEL-1855211 https://reactome.org/PathwayBrowser/#/R-CEL-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 18384 R-CFA-1855208 https://reactome.org/PathwayBrowser/#/R-CFA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Canis familiaris 18384 R-CFA-1855211 https://reactome.org/PathwayBrowser/#/R-CFA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 18384 R-DDI-1855208 https://reactome.org/PathwayBrowser/#/R-DDI-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Dictyostelium discoideum 18384 R-DDI-1855211 https://reactome.org/PathwayBrowser/#/R-DDI-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 18384 R-DME-1855208 https://reactome.org/PathwayBrowser/#/R-DME-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Drosophila melanogaster 18384 R-DME-1855211 https://reactome.org/PathwayBrowser/#/R-DME-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 18384 R-DRE-1855211 https://reactome.org/PathwayBrowser/#/R-DRE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 18384 R-GGA-1855208 https://reactome.org/PathwayBrowser/#/R-GGA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Gallus gallus 18384 R-GGA-1855211 https://reactome.org/PathwayBrowser/#/R-GGA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 18384 R-HSA-1855208 https://reactome.org/PathwayBrowser/#/R-HSA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol TAS Homo sapiens 18384 R-HSA-1855211 https://reactome.org/PathwayBrowser/#/R-HSA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 18384 R-MMU-1855208 https://reactome.org/PathwayBrowser/#/R-MMU-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Mus musculus 18384 R-MMU-1855211 https://reactome.org/PathwayBrowser/#/R-MMU-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 18384 R-RNO-1855208 https://reactome.org/PathwayBrowser/#/R-RNO-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Rattus norvegicus 18384 R-RNO-1855211 https://reactome.org/PathwayBrowser/#/R-RNO-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 18384 R-SCE-1855211 https://reactome.org/PathwayBrowser/#/R-SCE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 18384 R-SSC-1855208 https://reactome.org/PathwayBrowser/#/R-SSC-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Sus scrofa 18384 R-SSC-1855211 https://reactome.org/PathwayBrowser/#/R-SSC-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 18384 R-XTR-1855211 https://reactome.org/PathwayBrowser/#/R-XTR-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 18385 R-BTA-196761 https://reactome.org/PathwayBrowser/#/R-BTA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Bos taurus 18385 R-BTA-199626 https://reactome.org/PathwayBrowser/#/R-BTA-199626 SLC19A2/3 transport extracellular THMN to cytosol IEA Bos taurus 18385 R-CEL-196761 https://reactome.org/PathwayBrowser/#/R-CEL-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Caenorhabditis elegans 18385 R-CEL-199626 https://reactome.org/PathwayBrowser/#/R-CEL-199626 SLC19A2/3 transport extracellular THMN to cytosol IEA Caenorhabditis elegans 18385 R-CFA-196761 https://reactome.org/PathwayBrowser/#/R-CFA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Canis familiaris 18385 R-CFA-199626 https://reactome.org/PathwayBrowser/#/R-CFA-199626 SLC19A2/3 transport extracellular THMN to cytosol IEA Canis familiaris 18385 R-DDI-196761 https://reactome.org/PathwayBrowser/#/R-DDI-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Dictyostelium discoideum 18385 R-DDI-199626 https://reactome.org/PathwayBrowser/#/R-DDI-199626 SLC19A2/3 transport extracellular THMN to cytosol IEA Dictyostelium discoideum 18385 R-DME-196761 https://reactome.org/PathwayBrowser/#/R-DME-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Drosophila melanogaster 18385 R-DME-199626 https://reactome.org/PathwayBrowser/#/R-DME-199626 SLC19A2/3 transport extracellular THMN to cytosol IEA Drosophila melanogaster 18385 R-DRE-196761 https://reactome.org/PathwayBrowser/#/R-DRE-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Danio rerio 18385 R-GGA-196761 https://reactome.org/PathwayBrowser/#/R-GGA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Gallus gallus 18385 R-GGA-199626 https://reactome.org/PathwayBrowser/#/R-GGA-199626 SLC19A2/3 transport extracellular THMN to cytosol IEA Gallus gallus 18385 R-HSA-196761 https://reactome.org/PathwayBrowser/#/R-HSA-196761 2xTPK1:Mg2+ phosphorylates THMN TAS Homo sapiens 18385 R-HSA-199626 https://reactome.org/PathwayBrowser/#/R-HSA-199626 SLC19A2/3 transport extracellular THMN to cytosol TAS Homo sapiens 18385 R-MMU-196761 https://reactome.org/PathwayBrowser/#/R-MMU-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Mus musculus 18385 R-MMU-199626 https://reactome.org/PathwayBrowser/#/R-MMU-199626 SLC19A2/3 transport extracellular THMN to cytosol IEA Mus musculus 18385 R-PFA-196761 https://reactome.org/PathwayBrowser/#/R-PFA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Plasmodium falciparum 18385 R-RNO-196761 https://reactome.org/PathwayBrowser/#/R-RNO-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Rattus norvegicus 18385 R-RNO-199626 https://reactome.org/PathwayBrowser/#/R-RNO-199626 SLC19A2/3 transport extracellular THMN to cytosol IEA Rattus norvegicus 18385 R-SCE-196761 https://reactome.org/PathwayBrowser/#/R-SCE-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Saccharomyces cerevisiae 18385 R-SPO-196761 https://reactome.org/PathwayBrowser/#/R-SPO-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Schizosaccharomyces pombe 18385 R-SSC-196761 https://reactome.org/PathwayBrowser/#/R-SSC-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Sus scrofa 18385 R-SSC-199626 https://reactome.org/PathwayBrowser/#/R-SSC-199626 SLC19A2/3 transport extracellular THMN to cytosol IEA Sus scrofa 18385 R-XTR-196761 https://reactome.org/PathwayBrowser/#/R-XTR-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Xenopus tropicalis 18385 R-XTR-199626 https://reactome.org/PathwayBrowser/#/R-XTR-199626 SLC19A2/3 transport extracellular THMN to cytosol IEA Xenopus tropicalis 18396 R-BTA-446208 https://reactome.org/PathwayBrowser/#/R-BTA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Bos taurus 18396 R-BTA-446218 https://reactome.org/PathwayBrowser/#/R-BTA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Bos taurus 18396 R-CEL-446208 https://reactome.org/PathwayBrowser/#/R-CEL-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Caenorhabditis elegans 18396 R-CEL-446218 https://reactome.org/PathwayBrowser/#/R-CEL-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Caenorhabditis elegans 18396 R-CFA-446208 https://reactome.org/PathwayBrowser/#/R-CFA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Canis familiaris 18396 R-CFA-446218 https://reactome.org/PathwayBrowser/#/R-CFA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Canis familiaris 18396 R-DDI-446208 https://reactome.org/PathwayBrowser/#/R-DDI-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Dictyostelium discoideum 18396 R-DDI-446218 https://reactome.org/PathwayBrowser/#/R-DDI-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Dictyostelium discoideum 18396 R-DME-446208 https://reactome.org/PathwayBrowser/#/R-DME-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Drosophila melanogaster 18396 R-DME-446218 https://reactome.org/PathwayBrowser/#/R-DME-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Drosophila melanogaster 18396 R-DRE-446218 https://reactome.org/PathwayBrowser/#/R-DRE-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Danio rerio 18396 R-GGA-446208 https://reactome.org/PathwayBrowser/#/R-GGA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Gallus gallus 18396 R-GGA-446218 https://reactome.org/PathwayBrowser/#/R-GGA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Gallus gallus 18396 R-HSA-446208 https://reactome.org/PathwayBrowser/#/R-HSA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 TAS Homo sapiens 18396 R-HSA-446218 https://reactome.org/PathwayBrowser/#/R-HSA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 TAS Homo sapiens 18396 R-HSA-4549368 https://reactome.org/PathwayBrowser/#/R-HSA-4549368 Defective ALG2 does not transfer a second Man to N-glycan precursor TAS Homo sapiens 18396 R-MMU-446208 https://reactome.org/PathwayBrowser/#/R-MMU-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Mus musculus 18396 R-MMU-446218 https://reactome.org/PathwayBrowser/#/R-MMU-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Mus musculus 18396 R-RNO-446208 https://reactome.org/PathwayBrowser/#/R-RNO-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Rattus norvegicus 18396 R-RNO-446218 https://reactome.org/PathwayBrowser/#/R-RNO-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Rattus norvegicus 18396 R-SCE-446208 https://reactome.org/PathwayBrowser/#/R-SCE-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Saccharomyces cerevisiae 18396 R-SCE-446218 https://reactome.org/PathwayBrowser/#/R-SCE-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Saccharomyces cerevisiae 18396 R-SPO-446208 https://reactome.org/PathwayBrowser/#/R-SPO-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Schizosaccharomyces pombe 18396 R-SPO-446218 https://reactome.org/PathwayBrowser/#/R-SPO-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Schizosaccharomyces pombe 18396 R-SSC-446208 https://reactome.org/PathwayBrowser/#/R-SSC-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Sus scrofa 18396 R-SSC-446218 https://reactome.org/PathwayBrowser/#/R-SSC-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Sus scrofa 18396 R-XTR-446208 https://reactome.org/PathwayBrowser/#/R-XTR-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Xenopus tropicalis 18397 R-BTA-141200 https://reactome.org/PathwayBrowser/#/R-BTA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Bos taurus 18397 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 18397 R-BTA-391211 https://reactome.org/PathwayBrowser/#/R-BTA-391211 Trace amine-associated receptors can bind trace amines IEA Bos taurus 18397 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 18397 R-CEL-391211 https://reactome.org/PathwayBrowser/#/R-CEL-391211 Trace amine-associated receptors can bind trace amines IEA Caenorhabditis elegans 18397 R-CFA-141200 https://reactome.org/PathwayBrowser/#/R-CFA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Canis familiaris 18397 R-DDI-141200 https://reactome.org/PathwayBrowser/#/R-DDI-141200 MAOB:FAD oxidatively deaminates of PEA IEA Dictyostelium discoideum 18397 R-DRE-141200 https://reactome.org/PathwayBrowser/#/R-DRE-141200 MAOB:FAD oxidatively deaminates of PEA IEA Danio rerio 18397 R-DRE-391211 https://reactome.org/PathwayBrowser/#/R-DRE-391211 Trace amine-associated receptors can bind trace amines IEA Danio rerio 18397 R-GGA-141200 https://reactome.org/PathwayBrowser/#/R-GGA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Gallus gallus 18397 R-HSA-141200 https://reactome.org/PathwayBrowser/#/R-HSA-141200 MAOB:FAD oxidatively deaminates of PEA TAS Homo sapiens 18397 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 18397 R-HSA-391211 https://reactome.org/PathwayBrowser/#/R-HSA-391211 Trace amine-associated receptors can bind trace amines TAS Homo sapiens 18397 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 18397 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 18397 R-MMU-141200 https://reactome.org/PathwayBrowser/#/R-MMU-141200 MAOB:FAD oxidatively deaminates of PEA IEA Mus musculus 18397 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 18397 R-MMU-391211 https://reactome.org/PathwayBrowser/#/R-MMU-391211 Trace amine-associated receptors can bind trace amines IEA Mus musculus 18397 R-RNO-141200 https://reactome.org/PathwayBrowser/#/R-RNO-141200 MAOB:FAD oxidatively deaminates of PEA IEA Rattus norvegicus 18397 R-RNO-391211 https://reactome.org/PathwayBrowser/#/R-RNO-391211 Trace amine-associated receptors can bind trace amines IEA Rattus norvegicus 18397 R-SSC-141200 https://reactome.org/PathwayBrowser/#/R-SSC-141200 MAOB:FAD oxidatively deaminates of PEA IEA Sus scrofa 18397 R-XTR-141200 https://reactome.org/PathwayBrowser/#/R-XTR-141200 MAOB:FAD oxidatively deaminates of PEA IEA Xenopus tropicalis 18397 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 18397 R-XTR-391211 https://reactome.org/PathwayBrowser/#/R-XTR-391211 Trace amine-associated receptors can bind trace amines IEA Xenopus tropicalis 18402 R-BTA-192054 https://reactome.org/PathwayBrowser/#/R-BTA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Bos taurus 18402 R-BTA-192137 https://reactome.org/PathwayBrowser/#/R-BTA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 18402 R-BTA-193401 https://reactome.org/PathwayBrowser/#/R-BTA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 18402 R-CEL-192137 https://reactome.org/PathwayBrowser/#/R-CEL-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 18402 R-CEL-193401 https://reactome.org/PathwayBrowser/#/R-CEL-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 18402 R-CFA-192054 https://reactome.org/PathwayBrowser/#/R-CFA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Canis familiaris 18402 R-CFA-192137 https://reactome.org/PathwayBrowser/#/R-CFA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 18402 R-CFA-193401 https://reactome.org/PathwayBrowser/#/R-CFA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 18402 R-DME-192137 https://reactome.org/PathwayBrowser/#/R-DME-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 18402 R-DME-193401 https://reactome.org/PathwayBrowser/#/R-DME-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 18402 R-DRE-192137 https://reactome.org/PathwayBrowser/#/R-DRE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 18402 R-GGA-192137 https://reactome.org/PathwayBrowser/#/R-GGA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 18402 R-GGA-193401 https://reactome.org/PathwayBrowser/#/R-GGA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 18402 R-HSA-191971 https://reactome.org/PathwayBrowser/#/R-HSA-191971 THCA is translocated from the mitochondrial matrix to the cytosol TAS Homo sapiens 18402 R-HSA-192054 https://reactome.org/PathwayBrowser/#/R-HSA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) TAS Homo sapiens 18402 R-HSA-192137 https://reactome.org/PathwayBrowser/#/R-HSA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 18402 R-HSA-193401 https://reactome.org/PathwayBrowser/#/R-HSA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 18402 R-MMU-192054 https://reactome.org/PathwayBrowser/#/R-MMU-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Mus musculus 18402 R-MMU-192137 https://reactome.org/PathwayBrowser/#/R-MMU-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 18402 R-MMU-193401 https://reactome.org/PathwayBrowser/#/R-MMU-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 18402 R-RNO-192054 https://reactome.org/PathwayBrowser/#/R-RNO-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Rattus norvegicus 18402 R-RNO-192137 https://reactome.org/PathwayBrowser/#/R-RNO-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 18402 R-RNO-193401 https://reactome.org/PathwayBrowser/#/R-RNO-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 18402 R-SCE-192137 https://reactome.org/PathwayBrowser/#/R-SCE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 18402 R-SCE-193401 https://reactome.org/PathwayBrowser/#/R-SCE-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 18402 R-SSC-192054 https://reactome.org/PathwayBrowser/#/R-SSC-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Sus scrofa 18402 R-SSC-192137 https://reactome.org/PathwayBrowser/#/R-SSC-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 18402 R-SSC-193401 https://reactome.org/PathwayBrowser/#/R-SSC-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 18402 R-XTR-192137 https://reactome.org/PathwayBrowser/#/R-XTR-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 18402 R-XTR-193401 https://reactome.org/PathwayBrowser/#/R-XTR-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 18407 R-BTA-3149519 https://reactome.org/PathwayBrowser/#/R-BTA-3149519 MMACHC decyanates CNCbl IEA Bos taurus 18407 R-BTA-9013198 https://reactome.org/PathwayBrowser/#/R-BTA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Bos taurus 18407 R-BTA-9013471 https://reactome.org/PathwayBrowser/#/R-BTA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Bos taurus 18407 R-BTA-9013533 https://reactome.org/PathwayBrowser/#/R-BTA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Bos taurus 18407 R-CEL-3149519 https://reactome.org/PathwayBrowser/#/R-CEL-3149519 MMACHC decyanates CNCbl IEA Caenorhabditis elegans 18407 R-CEL-9013198 https://reactome.org/PathwayBrowser/#/R-CEL-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Caenorhabditis elegans 18407 R-CEL-9013471 https://reactome.org/PathwayBrowser/#/R-CEL-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Caenorhabditis elegans 18407 R-CEL-9013533 https://reactome.org/PathwayBrowser/#/R-CEL-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Caenorhabditis elegans 18407 R-CFA-3149519 https://reactome.org/PathwayBrowser/#/R-CFA-3149519 MMACHC decyanates CNCbl IEA Canis familiaris 18407 R-CFA-9013198 https://reactome.org/PathwayBrowser/#/R-CFA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Canis familiaris 18407 R-CFA-9013471 https://reactome.org/PathwayBrowser/#/R-CFA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Canis familiaris 18407 R-CFA-9013533 https://reactome.org/PathwayBrowser/#/R-CFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Canis familiaris 18407 R-DDI-3149519 https://reactome.org/PathwayBrowser/#/R-DDI-3149519 MMACHC decyanates CNCbl IEA Dictyostelium discoideum 18407 R-DDI-9013198 https://reactome.org/PathwayBrowser/#/R-DDI-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Dictyostelium discoideum 18407 R-DDI-9013471 https://reactome.org/PathwayBrowser/#/R-DDI-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Dictyostelium discoideum 18407 R-DDI-9013533 https://reactome.org/PathwayBrowser/#/R-DDI-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Dictyostelium discoideum 18407 R-DRE-3149519 https://reactome.org/PathwayBrowser/#/R-DRE-3149519 MMACHC decyanates CNCbl IEA Danio rerio 18407 R-DRE-9013198 https://reactome.org/PathwayBrowser/#/R-DRE-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Danio rerio 18407 R-DRE-9013471 https://reactome.org/PathwayBrowser/#/R-DRE-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Danio rerio 18407 R-DRE-9013533 https://reactome.org/PathwayBrowser/#/R-DRE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Danio rerio 18407 R-GGA-3149519 https://reactome.org/PathwayBrowser/#/R-GGA-3149519 MMACHC decyanates CNCbl IEA Gallus gallus 18407 R-GGA-9013198 https://reactome.org/PathwayBrowser/#/R-GGA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Gallus gallus 18407 R-GGA-9013471 https://reactome.org/PathwayBrowser/#/R-GGA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Gallus gallus 18407 R-GGA-9013533 https://reactome.org/PathwayBrowser/#/R-GGA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Gallus gallus 18407 R-HSA-3149519 https://reactome.org/PathwayBrowser/#/R-HSA-3149519 MMACHC decyanates CNCbl TAS Homo sapiens 18407 R-HSA-9013198 https://reactome.org/PathwayBrowser/#/R-HSA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN TAS Homo sapiens 18407 R-HSA-9013471 https://reactome.org/PathwayBrowser/#/R-HSA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN TAS Homo sapiens 18407 R-HSA-9013533 https://reactome.org/PathwayBrowser/#/R-HSA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN TAS Homo sapiens 18407 R-MMU-3149519 https://reactome.org/PathwayBrowser/#/R-MMU-3149519 MMACHC decyanates CNCbl IEA Mus musculus 18407 R-MMU-9013198 https://reactome.org/PathwayBrowser/#/R-MMU-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Mus musculus 18407 R-MMU-9013471 https://reactome.org/PathwayBrowser/#/R-MMU-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Mus musculus 18407 R-MMU-9013533 https://reactome.org/PathwayBrowser/#/R-MMU-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Mus musculus 18407 R-PFA-9013198 https://reactome.org/PathwayBrowser/#/R-PFA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Plasmodium falciparum 18407 R-PFA-9013471 https://reactome.org/PathwayBrowser/#/R-PFA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Plasmodium falciparum 18407 R-PFA-9013533 https://reactome.org/PathwayBrowser/#/R-PFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Plasmodium falciparum 18407 R-RNO-3149519 https://reactome.org/PathwayBrowser/#/R-RNO-3149519 MMACHC decyanates CNCbl IEA Rattus norvegicus 18407 R-RNO-9013198 https://reactome.org/PathwayBrowser/#/R-RNO-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Rattus norvegicus 18407 R-RNO-9013471 https://reactome.org/PathwayBrowser/#/R-RNO-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Rattus norvegicus 18407 R-RNO-9013533 https://reactome.org/PathwayBrowser/#/R-RNO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Rattus norvegicus 18407 R-SCE-9013198 https://reactome.org/PathwayBrowser/#/R-SCE-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Saccharomyces cerevisiae 18407 R-SCE-9013471 https://reactome.org/PathwayBrowser/#/R-SCE-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Saccharomyces cerevisiae 18407 R-SCE-9013533 https://reactome.org/PathwayBrowser/#/R-SCE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Saccharomyces cerevisiae 18407 R-SPO-9013198 https://reactome.org/PathwayBrowser/#/R-SPO-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Schizosaccharomyces pombe 18407 R-SPO-9013471 https://reactome.org/PathwayBrowser/#/R-SPO-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Schizosaccharomyces pombe 18407 R-SPO-9013533 https://reactome.org/PathwayBrowser/#/R-SPO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Schizosaccharomyces pombe 18407 R-SSC-3149519 https://reactome.org/PathwayBrowser/#/R-SSC-3149519 MMACHC decyanates CNCbl IEA Sus scrofa 18407 R-SSC-9013198 https://reactome.org/PathwayBrowser/#/R-SSC-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Sus scrofa 18407 R-SSC-9013471 https://reactome.org/PathwayBrowser/#/R-SSC-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Sus scrofa 18407 R-SSC-9013533 https://reactome.org/PathwayBrowser/#/R-SSC-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Sus scrofa 18407 R-XTR-3149519 https://reactome.org/PathwayBrowser/#/R-XTR-3149519 MMACHC decyanates CNCbl IEA Xenopus tropicalis 18407 R-XTR-9013198 https://reactome.org/PathwayBrowser/#/R-XTR-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Xenopus tropicalis 18407 R-XTR-9013471 https://reactome.org/PathwayBrowser/#/R-XTR-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Xenopus tropicalis 18407 R-XTR-9013533 https://reactome.org/PathwayBrowser/#/R-XTR-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Xenopus tropicalis 18408 R-BTA-3159253 https://reactome.org/PathwayBrowser/#/R-BTA-3159253 MMAB adenosylates cob(I)alamin IEA Bos taurus 18408 R-BTA-3159259 https://reactome.org/PathwayBrowser/#/R-BTA-3159259 MMAA:MUT binds AdoCbl IEA Bos taurus 18408 R-BTA-71010 https://reactome.org/PathwayBrowser/#/R-BTA-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Bos taurus 18408 R-CEL-3159253 https://reactome.org/PathwayBrowser/#/R-CEL-3159253 MMAB adenosylates cob(I)alamin IEA Caenorhabditis elegans 18408 R-CEL-3159259 https://reactome.org/PathwayBrowser/#/R-CEL-3159259 MMAA:MUT binds AdoCbl IEA Caenorhabditis elegans 18408 R-CEL-71010 https://reactome.org/PathwayBrowser/#/R-CEL-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Caenorhabditis elegans 18408 R-CFA-3159253 https://reactome.org/PathwayBrowser/#/R-CFA-3159253 MMAB adenosylates cob(I)alamin IEA Canis familiaris 18408 R-CFA-3159259 https://reactome.org/PathwayBrowser/#/R-CFA-3159259 MMAA:MUT binds AdoCbl IEA Canis familiaris 18408 R-CFA-71010 https://reactome.org/PathwayBrowser/#/R-CFA-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Canis familiaris 18408 R-DDI-3159253 https://reactome.org/PathwayBrowser/#/R-DDI-3159253 MMAB adenosylates cob(I)alamin IEA Dictyostelium discoideum 18408 R-DRE-3159259 https://reactome.org/PathwayBrowser/#/R-DRE-3159259 MMAA:MUT binds AdoCbl IEA Danio rerio 18408 R-DRE-71010 https://reactome.org/PathwayBrowser/#/R-DRE-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Danio rerio 18408 R-GGA-3159253 https://reactome.org/PathwayBrowser/#/R-GGA-3159253 MMAB adenosylates cob(I)alamin IEA Gallus gallus 18408 R-GGA-3159259 https://reactome.org/PathwayBrowser/#/R-GGA-3159259 MMAA:MUT binds AdoCbl IEA Gallus gallus 18408 R-GGA-71010 https://reactome.org/PathwayBrowser/#/R-GGA-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Gallus gallus 18408 R-HSA-3159253 https://reactome.org/PathwayBrowser/#/R-HSA-3159253 MMAB adenosylates cob(I)alamin TAS Homo sapiens 18408 R-HSA-3159259 https://reactome.org/PathwayBrowser/#/R-HSA-3159259 MMAA:MUT binds AdoCbl TAS Homo sapiens 18408 R-HSA-3322135 https://reactome.org/PathwayBrowser/#/R-HSA-3322135 Defective MMAA does not protect MUT TAS Homo sapiens 18408 R-HSA-3322971 https://reactome.org/PathwayBrowser/#/R-HSA-3322971 Defective MUT does not isomerise L-MM-CoA to SUCC-CoA TAS Homo sapiens 18408 R-HSA-71010 https://reactome.org/PathwayBrowser/#/R-HSA-71010 MUT isomerises L-MM-CoA to SUCC-CoA TAS Homo sapiens 18408 R-MMU-3159253 https://reactome.org/PathwayBrowser/#/R-MMU-3159253 MMAB adenosylates cob(I)alamin IEA Mus musculus 18408 R-MMU-3159259 https://reactome.org/PathwayBrowser/#/R-MMU-3159259 MMAA:MUT binds AdoCbl IEA Mus musculus 18408 R-MMU-71010 https://reactome.org/PathwayBrowser/#/R-MMU-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Mus musculus 18408 R-RNO-3159253 https://reactome.org/PathwayBrowser/#/R-RNO-3159253 MMAB adenosylates cob(I)alamin IEA Rattus norvegicus 18408 R-RNO-3159259 https://reactome.org/PathwayBrowser/#/R-RNO-3159259 MMAA:MUT binds AdoCbl IEA Rattus norvegicus 18408 R-RNO-71010 https://reactome.org/PathwayBrowser/#/R-RNO-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Rattus norvegicus 18408 R-SSC-3159253 https://reactome.org/PathwayBrowser/#/R-SSC-3159253 MMAB adenosylates cob(I)alamin IEA Sus scrofa 18408 R-SSC-3159259 https://reactome.org/PathwayBrowser/#/R-SSC-3159259 MMAA:MUT binds AdoCbl IEA Sus scrofa 18408 R-SSC-71010 https://reactome.org/PathwayBrowser/#/R-SSC-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Sus scrofa 18408 R-XTR-3159253 https://reactome.org/PathwayBrowser/#/R-XTR-3159253 MMAB adenosylates cob(I)alamin IEA Xenopus tropicalis 18420 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 18420 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 18420 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 18420 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 18420 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 18420 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 18420 R-BTA-109624 https://reactome.org/PathwayBrowser/#/R-BTA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Bos taurus 18420 R-BTA-109671 https://reactome.org/PathwayBrowser/#/R-BTA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Bos taurus 18420 R-BTA-111215 https://reactome.org/PathwayBrowser/#/R-BTA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Bos taurus 18420 R-BTA-111524 https://reactome.org/PathwayBrowser/#/R-BTA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Bos taurus 18420 R-BTA-111930 https://reactome.org/PathwayBrowser/#/R-BTA-111930 Adenylate cyclase produces cAMP IEA Bos taurus 18420 R-BTA-1237129 https://reactome.org/PathwayBrowser/#/R-BTA-1237129 Acireductone is created IEA Bos taurus 18420 R-BTA-1482961 https://reactome.org/PathwayBrowser/#/R-BTA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Bos taurus 18420 R-BTA-1482962 https://reactome.org/PathwayBrowser/#/R-BTA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Bos taurus 18420 R-BTA-1482973 https://reactome.org/PathwayBrowser/#/R-BTA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Bos taurus 18420 R-BTA-1482976 https://reactome.org/PathwayBrowser/#/R-BTA-1482976 CDP-DAG is converted to PI by CDIPT IEA Bos taurus 18420 R-BTA-1483096 https://reactome.org/PathwayBrowser/#/R-BTA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Bos taurus 18420 R-BTA-1483121 https://reactome.org/PathwayBrowser/#/R-BTA-1483121 PA is converted to CDP-DAG by CDS1 IEA Bos taurus 18420 R-BTA-1483159 https://reactome.org/PathwayBrowser/#/R-BTA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Bos taurus 18420 R-BTA-1483203 https://reactome.org/PathwayBrowser/#/R-BTA-1483203 PA is dephosphorylated to DAG by LPIN IEA Bos taurus 18420 R-BTA-1606273 https://reactome.org/PathwayBrowser/#/R-BTA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Bos taurus 18420 R-BTA-1606288 https://reactome.org/PathwayBrowser/#/R-BTA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Bos taurus 18420 R-BTA-163741 https://reactome.org/PathwayBrowser/#/R-BTA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Bos taurus 18420 R-BTA-163751 https://reactome.org/PathwayBrowser/#/R-BTA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Bos taurus 18420 R-BTA-1675928 https://reactome.org/PathwayBrowser/#/R-BTA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Bos taurus 18420 R-BTA-1675939 https://reactome.org/PathwayBrowser/#/R-BTA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Bos taurus 18420 R-BTA-1675961 https://reactome.org/PathwayBrowser/#/R-BTA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Bos taurus 18420 R-BTA-1676024 https://reactome.org/PathwayBrowser/#/R-BTA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Bos taurus 18420 R-BTA-1676109 https://reactome.org/PathwayBrowser/#/R-BTA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Bos taurus 18420 R-BTA-1676206 https://reactome.org/PathwayBrowser/#/R-BTA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Bos taurus 18420 R-BTA-170666 https://reactome.org/PathwayBrowser/#/R-BTA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Bos taurus 18420 R-BTA-170671 https://reactome.org/PathwayBrowser/#/R-BTA-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Bos taurus 18420 R-BTA-170672 https://reactome.org/PathwayBrowser/#/R-BTA-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Bos taurus 18420 R-BTA-170674 https://reactome.org/PathwayBrowser/#/R-BTA-170674 Dissociation of the Gi alpha:G olf complex IEA Bos taurus 18420 R-BTA-170676 https://reactome.org/PathwayBrowser/#/R-BTA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Bos taurus 18420 R-BTA-170677 https://reactome.org/PathwayBrowser/#/R-BTA-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Bos taurus 18420 R-BTA-170685 https://reactome.org/PathwayBrowser/#/R-BTA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Bos taurus 18420 R-BTA-170686 https://reactome.org/PathwayBrowser/#/R-BTA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Bos taurus 18420 R-BTA-174391 https://reactome.org/PathwayBrowser/#/R-BTA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Bos taurus 18420 R-BTA-174394 https://reactome.org/PathwayBrowser/#/R-BTA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Bos taurus 18420 R-BTA-1855154 https://reactome.org/PathwayBrowser/#/R-BTA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 18420 R-BTA-1855159 https://reactome.org/PathwayBrowser/#/R-BTA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Bos taurus 18420 R-BTA-1855162 https://reactome.org/PathwayBrowser/#/R-BTA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Bos taurus 18420 R-BTA-1855165 https://reactome.org/PathwayBrowser/#/R-BTA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 18420 R-BTA-1855166 https://reactome.org/PathwayBrowser/#/R-BTA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Bos taurus 18420 R-BTA-1855169 https://reactome.org/PathwayBrowser/#/R-BTA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Bos taurus 18420 R-BTA-1855171 https://reactome.org/PathwayBrowser/#/R-BTA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Bos taurus 18420 R-BTA-1855172 https://reactome.org/PathwayBrowser/#/R-BTA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Bos taurus 18420 R-BTA-1855197 https://reactome.org/PathwayBrowser/#/R-BTA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Bos taurus 18420 R-BTA-1855198 https://reactome.org/PathwayBrowser/#/R-BTA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 18420 R-BTA-1855205 https://reactome.org/PathwayBrowser/#/R-BTA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Bos taurus 18420 R-BTA-1855208 https://reactome.org/PathwayBrowser/#/R-BTA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Bos taurus 18420 R-BTA-1855210 https://reactome.org/PathwayBrowser/#/R-BTA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 18420 R-BTA-1855211 https://reactome.org/PathwayBrowser/#/R-BTA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 18420 R-BTA-1855218 https://reactome.org/PathwayBrowser/#/R-BTA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Bos taurus 18420 R-BTA-1855219 https://reactome.org/PathwayBrowser/#/R-BTA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Bos taurus 18420 R-BTA-1855232 https://reactome.org/PathwayBrowser/#/R-BTA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Bos taurus 18420 R-BTA-187688 https://reactome.org/PathwayBrowser/#/R-BTA-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Bos taurus 18420 R-BTA-191382 https://reactome.org/PathwayBrowser/#/R-BTA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Bos taurus 18420 R-BTA-191402 https://reactome.org/PathwayBrowser/#/R-BTA-191402 Reduction of presqualene diphosphate to form squalene IEA Bos taurus 18420 R-BTA-191405 https://reactome.org/PathwayBrowser/#/R-BTA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Bos taurus 18420 R-BTA-196761 https://reactome.org/PathwayBrowser/#/R-BTA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Bos taurus 18420 R-BTA-196964 https://reactome.org/PathwayBrowser/#/R-BTA-196964 RFK:Mg2+ phosphorylates RIB IEA Bos taurus 18420 R-BTA-197186 https://reactome.org/PathwayBrowser/#/R-BTA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Bos taurus 18420 R-BTA-197235 https://reactome.org/PathwayBrowser/#/R-BTA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 18420 R-BTA-200474 https://reactome.org/PathwayBrowser/#/R-BTA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 18420 R-BTA-2023971 https://reactome.org/PathwayBrowser/#/R-BTA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 18420 R-BTA-2023973 https://reactome.org/PathwayBrowser/#/R-BTA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 18420 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 18420 R-BTA-204169 https://reactome.org/PathwayBrowser/#/R-BTA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Bos taurus 18420 R-BTA-2046085 https://reactome.org/PathwayBrowser/#/R-BTA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Bos taurus 18420 R-BTA-2046098 https://reactome.org/PathwayBrowser/#/R-BTA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Bos taurus 18420 R-BTA-216043 https://reactome.org/PathwayBrowser/#/R-BTA-216043 Collagen type II binds integrin alpha10beta1 IEA Bos taurus 18420 R-BTA-216045 https://reactome.org/PathwayBrowser/#/R-BTA-216045 Collagen type I binds integrin alpha11beta1 IEA Bos taurus 18420 R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Bos taurus 18420 R-BTA-2162066 https://reactome.org/PathwayBrowser/#/R-BTA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Bos taurus 18420 R-BTA-2162253 https://reactome.org/PathwayBrowser/#/R-BTA-2162253 PDSS1,2 ligates FPP to IPPP IEA Bos taurus 18420 R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 18420 R-BTA-2393939 https://reactome.org/PathwayBrowser/#/R-BTA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 18420 R-BTA-2393954 https://reactome.org/PathwayBrowser/#/R-BTA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 18420 R-BTA-2395818 https://reactome.org/PathwayBrowser/#/R-BTA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Bos taurus 18420 R-BTA-2395849 https://reactome.org/PathwayBrowser/#/R-BTA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 18420 R-BTA-2395872 https://reactome.org/PathwayBrowser/#/R-BTA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Bos taurus 18420 R-BTA-2408551 https://reactome.org/PathwayBrowser/#/R-BTA-2408551 SeMet is converted to AdoSeMet by MAT IEA Bos taurus 18420 R-BTA-2509793 https://reactome.org/PathwayBrowser/#/R-BTA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Bos taurus 18420 R-BTA-2509816 https://reactome.org/PathwayBrowser/#/R-BTA-2509816 NUDT16 hydrolyses IDP to IMP IEA Bos taurus 18420 R-BTA-2509827 https://reactome.org/PathwayBrowser/#/R-BTA-2509827 ITPA hydrolyses ITP to IMP IEA Bos taurus 18420 R-BTA-2509831 https://reactome.org/PathwayBrowser/#/R-BTA-2509831 ITPA hydrolyses XTP to XMP IEA Bos taurus 18420 R-BTA-2509838 https://reactome.org/PathwayBrowser/#/R-BTA-2509838 ITPA hydrolyses dITP to dIMP IEA Bos taurus 18420 R-BTA-265682 https://reactome.org/PathwayBrowser/#/R-BTA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Bos taurus 18420 R-BTA-3322001 https://reactome.org/PathwayBrowser/#/R-BTA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Bos taurus 18420 R-BTA-3322003 https://reactome.org/PathwayBrowser/#/R-BTA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Bos taurus 18420 R-BTA-3322005 https://reactome.org/PathwayBrowser/#/R-BTA-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Bos taurus 18420 R-BTA-3322009 https://reactome.org/PathwayBrowser/#/R-BTA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Bos taurus 18420 R-BTA-3322014 https://reactome.org/PathwayBrowser/#/R-BTA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Bos taurus 18420 R-BTA-3322016 https://reactome.org/PathwayBrowser/#/R-BTA-3322016 GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a IEA Bos taurus 18420 R-BTA-3322019 https://reactome.org/PathwayBrowser/#/R-BTA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Bos taurus 18420 R-BTA-3322025 https://reactome.org/PathwayBrowser/#/R-BTA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Bos taurus 18420 R-BTA-3322041 https://reactome.org/PathwayBrowser/#/R-BTA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Bos taurus 18420 R-BTA-3322057 https://reactome.org/PathwayBrowser/#/R-BTA-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Bos taurus 18420 R-BTA-354066 https://reactome.org/PathwayBrowser/#/R-BTA-354066 Translocation of PTK2 to Focal complexes IEA Bos taurus 18420 R-BTA-354073 https://reactome.org/PathwayBrowser/#/R-BTA-354073 Autophosphorylation of PTK2 at Y397 IEA Bos taurus 18420 R-BTA-354087 https://reactome.org/PathwayBrowser/#/R-BTA-354087 Recruitment of GRB2 to p-PTK2 IEA Bos taurus 18420 R-BTA-354124 https://reactome.org/PathwayBrowser/#/R-BTA-354124 Phosphorylation of pPTK2 by SRC IEA Bos taurus 18420 R-BTA-354149 https://reactome.org/PathwayBrowser/#/R-BTA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Bos taurus 18420 R-BTA-354165 https://reactome.org/PathwayBrowser/#/R-BTA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Bos taurus 18420 R-BTA-372693 https://reactome.org/PathwayBrowser/#/R-BTA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Bos taurus 18420 R-BTA-372697 https://reactome.org/PathwayBrowser/#/R-BTA-372697 Crk binding to p130cas IEA Bos taurus 18420 R-BTA-372705 https://reactome.org/PathwayBrowser/#/R-BTA-372705 Recruitment of BCAR1 to PTK2 complex IEA Bos taurus 18420 R-BTA-377640 https://reactome.org/PathwayBrowser/#/R-BTA-377640 Autophosphorylation of SRC IEA Bos taurus 18420 R-BTA-377641 https://reactome.org/PathwayBrowser/#/R-BTA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Bos taurus 18420 R-BTA-377643 https://reactome.org/PathwayBrowser/#/R-BTA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Bos taurus 18420 R-BTA-377644 https://reactome.org/PathwayBrowser/#/R-BTA-377644 Release of CSK from SRC IEA Bos taurus 18420 R-BTA-3780994 https://reactome.org/PathwayBrowser/#/R-BTA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Bos taurus 18420 R-BTA-3780997 https://reactome.org/PathwayBrowser/#/R-BTA-3780997 PPP1R3C binds to glycogen:GYG2:GYS2 IEA Bos taurus 18420 R-BTA-3781011 https://reactome.org/PathwayBrowser/#/R-BTA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Bos taurus 18420 R-BTA-3781018 https://reactome.org/PathwayBrowser/#/R-BTA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Bos taurus 18420 R-BTA-3781023 https://reactome.org/PathwayBrowser/#/R-BTA-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Bos taurus 18420 R-BTA-3781024 https://reactome.org/PathwayBrowser/#/R-BTA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Bos taurus 18420 R-BTA-3858495 https://reactome.org/PathwayBrowser/#/R-BTA-3858495 DAAM1 recruits GTP-bound RHOA IEA Bos taurus 18420 R-BTA-389611 https://reactome.org/PathwayBrowser/#/R-BTA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Bos taurus 18420 R-BTA-392064 https://reactome.org/PathwayBrowser/#/R-BTA-392064 G alpha (z) inhibits adenylate cyclase IEA Bos taurus 18420 R-BTA-4084989 https://reactome.org/PathwayBrowser/#/R-BTA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Bos taurus 18420 R-BTA-426223 https://reactome.org/PathwayBrowser/#/R-BTA-426223 Cation influx mediated by TRPC3/6/7 IEA Bos taurus 18420 R-BTA-429415 https://reactome.org/PathwayBrowser/#/R-BTA-429415 SYK binds to integrin alphaIIb beta3 IEA Bos taurus 18420 R-BTA-429441 https://reactome.org/PathwayBrowser/#/R-BTA-429441 SYK activation by SRC IEA Bos taurus 18420 R-BTA-442661 https://reactome.org/PathwayBrowser/#/R-BTA-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol IEA Bos taurus 18420 R-BTA-449937 https://reactome.org/PathwayBrowser/#/R-BTA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Bos taurus 18420 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 18420 R-BTA-5218804 https://reactome.org/PathwayBrowser/#/R-BTA-5218804 p38 MAPK activation by VEGFR IEA Bos taurus 18420 R-BTA-5218826 https://reactome.org/PathwayBrowser/#/R-BTA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Bos taurus 18420 R-BTA-5228992 https://reactome.org/PathwayBrowser/#/R-BTA-5228992 ROCK1,ROCK2 are activated IEA Bos taurus 18420 R-BTA-5336453 https://reactome.org/PathwayBrowser/#/R-BTA-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Bos taurus 18420 R-BTA-5336466 https://reactome.org/PathwayBrowser/#/R-BTA-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Bos taurus 18420 R-BTA-5339528 https://reactome.org/PathwayBrowser/#/R-BTA-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Bos taurus 18420 R-BTA-5339538 https://reactome.org/PathwayBrowser/#/R-BTA-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Bos taurus 18420 R-BTA-5603114 https://reactome.org/PathwayBrowser/#/R-BTA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Bos taurus 18420 R-BTA-5610727 https://reactome.org/PathwayBrowser/#/R-BTA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Bos taurus 18420 R-BTA-5655835 https://reactome.org/PathwayBrowser/#/R-BTA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Bos taurus 18420 R-BTA-5655892 https://reactome.org/PathwayBrowser/#/R-BTA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Bos taurus 18420 R-BTA-5655965 https://reactome.org/PathwayBrowser/#/R-BTA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Bos taurus 18420 R-BTA-5656105 https://reactome.org/PathwayBrowser/#/R-BTA-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Bos taurus 18420 R-BTA-5656148 https://reactome.org/PathwayBrowser/#/R-BTA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Bos taurus 18420 R-BTA-5656158 https://reactome.org/PathwayBrowser/#/R-BTA-5656158 POLZ elongates POLI-incorporated dNMP IEA Bos taurus 18420 R-BTA-5672972 https://reactome.org/PathwayBrowser/#/R-BTA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Bos taurus 18420 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 18420 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 18420 R-BTA-5672980 https://reactome.org/PathwayBrowser/#/R-BTA-5672980 Dissociation of RAS:RAF complex IEA Bos taurus 18420 R-BTA-5694018 https://reactome.org/PathwayBrowser/#/R-BTA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Bos taurus 18420 R-BTA-5696021 https://reactome.org/PathwayBrowser/#/R-BTA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Bos taurus 18420 R-BTA-5696074 https://reactome.org/PathwayBrowser/#/R-BTA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Bos taurus 18420 R-BTA-6787329 https://reactome.org/PathwayBrowser/#/R-BTA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Bos taurus 18420 R-BTA-6788295 https://reactome.org/PathwayBrowser/#/R-BTA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Bos taurus 18420 R-BTA-6788597 https://reactome.org/PathwayBrowser/#/R-BTA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Bos taurus 18420 R-BTA-6788912 https://reactome.org/PathwayBrowser/#/R-BTA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Bos taurus 18420 R-BTA-70349 https://reactome.org/PathwayBrowser/#/R-BTA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Bos taurus 18420 R-BTA-70479 https://reactome.org/PathwayBrowser/#/R-BTA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Bos taurus 18420 R-BTA-70486 https://reactome.org/PathwayBrowser/#/R-BTA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Bos taurus 18420 R-BTA-70494 https://reactome.org/PathwayBrowser/#/R-BTA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Bos taurus 18420 R-BTA-70997 https://reactome.org/PathwayBrowser/#/R-BTA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Bos taurus 18420 R-BTA-71037 https://reactome.org/PathwayBrowser/#/R-BTA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Bos taurus 18420 R-BTA-71181 https://reactome.org/PathwayBrowser/#/R-BTA-71181 FAH cleaves 4FAA IEA Bos taurus 18420 R-BTA-71324 https://reactome.org/PathwayBrowser/#/R-BTA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 18420 R-BTA-71335 https://reactome.org/PathwayBrowser/#/R-BTA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Bos taurus 18420 R-BTA-71401 https://reactome.org/PathwayBrowser/#/R-BTA-71401 OGDH dimer decarboxylates 2-OG IEA Bos taurus 18420 R-BTA-71660 https://reactome.org/PathwayBrowser/#/R-BTA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Bos taurus 18420 R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 18420 R-BTA-71732 https://reactome.org/PathwayBrowser/#/R-BTA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Bos taurus 18420 R-BTA-71775 https://reactome.org/PathwayBrowser/#/R-BTA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Bos taurus 18420 R-BTA-71850 https://reactome.org/PathwayBrowser/#/R-BTA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Bos taurus 18420 R-BTA-73598 https://reactome.org/PathwayBrowser/#/R-BTA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Bos taurus 18420 R-BTA-73605 https://reactome.org/PathwayBrowser/#/R-BTA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Bos taurus 18420 R-BTA-74215 https://reactome.org/PathwayBrowser/#/R-BTA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Bos taurus 18420 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 18420 R-BTA-74948 https://reactome.org/PathwayBrowser/#/R-BTA-74948 PP2A dephosphorylates p-RHO to RHO IEA Bos taurus 18420 R-BTA-8850846 https://reactome.org/PathwayBrowser/#/R-BTA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Bos taurus 18420 R-BTA-8850854 https://reactome.org/PathwayBrowser/#/R-BTA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Bos taurus 18420 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 18420 R-BTA-8851110 https://reactome.org/PathwayBrowser/#/R-BTA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Bos taurus 18420 R-BTA-8851129 https://reactome.org/PathwayBrowser/#/R-BTA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Bos taurus 18420 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 18420 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 18420 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 18420 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 18420 R-BTA-8939959 https://reactome.org/PathwayBrowser/#/R-BTA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Bos taurus 18420 R-BTA-8953499 https://reactome.org/PathwayBrowser/#/R-BTA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Bos taurus 18420 R-BTA-8955760 https://reactome.org/PathwayBrowser/#/R-BTA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Bos taurus 18420 R-BTA-8982667 https://reactome.org/PathwayBrowser/#/R-BTA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Bos taurus 18420 R-BTA-9012016 https://reactome.org/PathwayBrowser/#/R-BTA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Bos taurus 18420 R-BTA-9012036 https://reactome.org/PathwayBrowser/#/R-BTA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Bos taurus 18420 R-BTA-9012268 https://reactome.org/PathwayBrowser/#/R-BTA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Bos taurus 18420 R-BTA-9012349 https://reactome.org/PathwayBrowser/#/R-BTA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Bos taurus 18420 R-BTA-9014741 https://reactome.org/PathwayBrowser/#/R-BTA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Bos taurus 18420 R-BTA-9014766 https://reactome.org/PathwayBrowser/#/R-BTA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Bos taurus 18420 R-BTA-9024993 https://reactome.org/PathwayBrowser/#/R-BTA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Bos taurus 18420 R-BTA-936883 https://reactome.org/PathwayBrowser/#/R-BTA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Bos taurus 18420 R-BTA-947531 https://reactome.org/PathwayBrowser/#/R-BTA-947531 Molybdenum ion transfer onto molybdopterin IEA Bos taurus 18420 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 18420 R-BTA-9621179 https://reactome.org/PathwayBrowser/#/R-BTA-9621179 Cinaciguat binds sGC:NO IEA Bos taurus 18420 R-BTA-965067 https://reactome.org/PathwayBrowser/#/R-BTA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Bos taurus 18420 R-BTA-9650858 https://reactome.org/PathwayBrowser/#/R-BTA-9650858 Meglitinides bind ABCC8 IEA Bos taurus 18420 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 18420 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus 18420 R-BTA-9657603 https://reactome.org/PathwayBrowser/#/R-BTA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Bos taurus 18420 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 18420 R-BTA-9657608 https://reactome.org/PathwayBrowser/#/R-BTA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Bos taurus 18420 R-BTA-9717830 https://reactome.org/PathwayBrowser/#/R-BTA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Bos taurus 18420 R-BTA-9717834 https://reactome.org/PathwayBrowser/#/R-BTA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Bos taurus 18420 R-BTA-9731228 https://reactome.org/PathwayBrowser/#/R-BTA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Bos taurus 18420 R-BTA-9731590 https://reactome.org/PathwayBrowser/#/R-BTA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Bos taurus 18420 R-BTA-9731613 https://reactome.org/PathwayBrowser/#/R-BTA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Bos taurus 18420 R-BTA-9731632 https://reactome.org/PathwayBrowser/#/R-BTA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Bos taurus 18420 R-BTA-9748951 https://reactome.org/PathwayBrowser/#/R-BTA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Bos taurus 18420 R-BTA-9754916 https://reactome.org/PathwayBrowser/#/R-BTA-9754916 NT5C2 tetramer phosphorylates RBV IEA Bos taurus 18420 R-BTA-9754974 https://reactome.org/PathwayBrowser/#/R-BTA-9754974 ADK phosphorylates RBV IEA Bos taurus 18420 R-BTA-9755078 https://reactome.org/PathwayBrowser/#/R-BTA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Bos taurus 18420 R-BTA-9770141 https://reactome.org/PathwayBrowser/#/R-BTA-9770141 Formation of the Spliceosomal C* complex IEA Bos taurus 18420 R-BTA-9770145 https://reactome.org/PathwayBrowser/#/R-BTA-9770145 Formation of the Spliceosomal Bact complex IEA Bos taurus 18420 R-BTA-9770236 https://reactome.org/PathwayBrowser/#/R-BTA-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Bos taurus 18420 R-BTA-977324 https://reactome.org/PathwayBrowser/#/R-BTA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Bos taurus 18420 R-BTA-983153 https://reactome.org/PathwayBrowser/#/R-BTA-983153 E1 mediated ubiquitin activation IEA Bos taurus 18420 R-BTA-9853499 https://reactome.org/PathwayBrowser/#/R-BTA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 18420 R-BTA-9853512 https://reactome.org/PathwayBrowser/#/R-BTA-9853512 DLST transfers succinyl to CoA IEA Bos taurus 18420 R-BTA-9861616 https://reactome.org/PathwayBrowser/#/R-BTA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 18420 R-BTA-9861631 https://reactome.org/PathwayBrowser/#/R-BTA-9861631 ME1 tetramerizes IEA Bos taurus 18420 R-BTA-9861642 https://reactome.org/PathwayBrowser/#/R-BTA-9861642 NEK1 phosphorylates ME1 IEA Bos taurus 18420 R-BTA-9861660 https://reactome.org/PathwayBrowser/#/R-BTA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Bos taurus 18420 R-BTA-9861667 https://reactome.org/PathwayBrowser/#/R-BTA-9861667 DLAT trimer transfers acetyl to CoA IEA Bos taurus 18420 R-BTA-9861734 https://reactome.org/PathwayBrowser/#/R-BTA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Bos taurus 18420 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 18420 R-CEL-109624 https://reactome.org/PathwayBrowser/#/R-CEL-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Caenorhabditis elegans 18420 R-CEL-111524 https://reactome.org/PathwayBrowser/#/R-CEL-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Caenorhabditis elegans 18420 R-CEL-111930 https://reactome.org/PathwayBrowser/#/R-CEL-111930 Adenylate cyclase produces cAMP IEA Caenorhabditis elegans 18420 R-CEL-1237129 https://reactome.org/PathwayBrowser/#/R-CEL-1237129 Acireductone is created IEA Caenorhabditis elegans 18420 R-CEL-1482961 https://reactome.org/PathwayBrowser/#/R-CEL-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Caenorhabditis elegans 18420 R-CEL-1482962 https://reactome.org/PathwayBrowser/#/R-CEL-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Caenorhabditis elegans 18420 R-CEL-1482973 https://reactome.org/PathwayBrowser/#/R-CEL-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Caenorhabditis elegans 18420 R-CEL-1482976 https://reactome.org/PathwayBrowser/#/R-CEL-1482976 CDP-DAG is converted to PI by CDIPT IEA Caenorhabditis elegans 18420 R-CEL-1483121 https://reactome.org/PathwayBrowser/#/R-CEL-1483121 PA is converted to CDP-DAG by CDS1 IEA Caenorhabditis elegans 18420 R-CEL-1483203 https://reactome.org/PathwayBrowser/#/R-CEL-1483203 PA is dephosphorylated to DAG by LPIN IEA Caenorhabditis elegans 18420 R-CEL-1606273 https://reactome.org/PathwayBrowser/#/R-CEL-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Caenorhabditis elegans 18420 R-CEL-1606288 https://reactome.org/PathwayBrowser/#/R-CEL-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Caenorhabditis elegans 18420 R-CEL-163741 https://reactome.org/PathwayBrowser/#/R-CEL-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Caenorhabditis elegans 18420 R-CEL-163751 https://reactome.org/PathwayBrowser/#/R-CEL-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Caenorhabditis elegans 18420 R-CEL-170666 https://reactome.org/PathwayBrowser/#/R-CEL-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Caenorhabditis elegans 18420 R-CEL-170671 https://reactome.org/PathwayBrowser/#/R-CEL-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Caenorhabditis elegans 18420 R-CEL-170672 https://reactome.org/PathwayBrowser/#/R-CEL-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Caenorhabditis elegans 18420 R-CEL-170674 https://reactome.org/PathwayBrowser/#/R-CEL-170674 Dissociation of the Gi alpha:G olf complex IEA Caenorhabditis elegans 18420 R-CEL-170676 https://reactome.org/PathwayBrowser/#/R-CEL-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Caenorhabditis elegans 18420 R-CEL-170677 https://reactome.org/PathwayBrowser/#/R-CEL-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Caenorhabditis elegans 18420 R-CEL-170685 https://reactome.org/PathwayBrowser/#/R-CEL-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Caenorhabditis elegans 18420 R-CEL-170686 https://reactome.org/PathwayBrowser/#/R-CEL-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Caenorhabditis elegans 18420 R-CEL-174394 https://reactome.org/PathwayBrowser/#/R-CEL-174394 GSS:Mg2+ dimer synthesizes GSH IEA Caenorhabditis elegans 18420 R-CEL-1855154 https://reactome.org/PathwayBrowser/#/R-CEL-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 18420 R-CEL-1855165 https://reactome.org/PathwayBrowser/#/R-CEL-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 18420 R-CEL-1855166 https://reactome.org/PathwayBrowser/#/R-CEL-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Caenorhabditis elegans 18420 R-CEL-1855198 https://reactome.org/PathwayBrowser/#/R-CEL-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 18420 R-CEL-1855205 https://reactome.org/PathwayBrowser/#/R-CEL-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Caenorhabditis elegans 18420 R-CEL-1855210 https://reactome.org/PathwayBrowser/#/R-CEL-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 18420 R-CEL-1855211 https://reactome.org/PathwayBrowser/#/R-CEL-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 18420 R-CEL-187688 https://reactome.org/PathwayBrowser/#/R-CEL-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Caenorhabditis elegans 18420 R-CEL-191303 https://reactome.org/PathwayBrowser/#/R-CEL-191303 FDPS dimer transfers IPPP to GPP IEA Caenorhabditis elegans 18420 R-CEL-191322 https://reactome.org/PathwayBrowser/#/R-CEL-191322 FDPS dimer transfers IPPP to DMAPP IEA Caenorhabditis elegans 18420 R-CEL-191382 https://reactome.org/PathwayBrowser/#/R-CEL-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Caenorhabditis elegans 18420 R-CEL-196761 https://reactome.org/PathwayBrowser/#/R-CEL-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Caenorhabditis elegans 18420 R-CEL-196964 https://reactome.org/PathwayBrowser/#/R-CEL-196964 RFK:Mg2+ phosphorylates RIB IEA Caenorhabditis elegans 18420 R-CEL-197186 https://reactome.org/PathwayBrowser/#/R-CEL-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Caenorhabditis elegans 18420 R-CEL-197235 https://reactome.org/PathwayBrowser/#/R-CEL-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 18420 R-CEL-200474 https://reactome.org/PathwayBrowser/#/R-CEL-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 18420 R-CEL-2023971 https://reactome.org/PathwayBrowser/#/R-CEL-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 18420 R-CEL-2023973 https://reactome.org/PathwayBrowser/#/R-CEL-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 18420 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 18420 R-CEL-204169 https://reactome.org/PathwayBrowser/#/R-CEL-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Caenorhabditis elegans 18420 R-CEL-216043 https://reactome.org/PathwayBrowser/#/R-CEL-216043 Collagen type II binds integrin alpha10beta1 IEA Caenorhabditis elegans 18420 R-CEL-216045 https://reactome.org/PathwayBrowser/#/R-CEL-216045 Collagen type I binds integrin alpha11beta1 IEA Caenorhabditis elegans 18420 R-CEL-2162066 https://reactome.org/PathwayBrowser/#/R-CEL-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Caenorhabditis elegans 18420 R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 18420 R-CEL-2393939 https://reactome.org/PathwayBrowser/#/R-CEL-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 18420 R-CEL-2393954 https://reactome.org/PathwayBrowser/#/R-CEL-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 18420 R-CEL-2509827 https://reactome.org/PathwayBrowser/#/R-CEL-2509827 ITPA hydrolyses ITP to IMP IEA Caenorhabditis elegans 18420 R-CEL-2509831 https://reactome.org/PathwayBrowser/#/R-CEL-2509831 ITPA hydrolyses XTP to XMP IEA Caenorhabditis elegans 18420 R-CEL-2509838 https://reactome.org/PathwayBrowser/#/R-CEL-2509838 ITPA hydrolyses dITP to dIMP IEA Caenorhabditis elegans 18420 R-CEL-3322001 https://reactome.org/PathwayBrowser/#/R-CEL-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Caenorhabditis elegans 18420 R-CEL-3322003 https://reactome.org/PathwayBrowser/#/R-CEL-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Caenorhabditis elegans 18420 R-CEL-3322005 https://reactome.org/PathwayBrowser/#/R-CEL-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Caenorhabditis elegans 18420 R-CEL-3322009 https://reactome.org/PathwayBrowser/#/R-CEL-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Caenorhabditis elegans 18420 R-CEL-3322014 https://reactome.org/PathwayBrowser/#/R-CEL-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Caenorhabditis elegans 18420 R-CEL-3322016 https://reactome.org/PathwayBrowser/#/R-CEL-3322016 GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a IEA Caenorhabditis elegans 18420 R-CEL-3322019 https://reactome.org/PathwayBrowser/#/R-CEL-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Caenorhabditis elegans 18420 R-CEL-3322025 https://reactome.org/PathwayBrowser/#/R-CEL-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Caenorhabditis elegans 18420 R-CEL-3322041 https://reactome.org/PathwayBrowser/#/R-CEL-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Caenorhabditis elegans 18420 R-CEL-3322057 https://reactome.org/PathwayBrowser/#/R-CEL-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Caenorhabditis elegans 18420 R-CEL-354066 https://reactome.org/PathwayBrowser/#/R-CEL-354066 Translocation of PTK2 to Focal complexes IEA Caenorhabditis elegans 18420 R-CEL-354073 https://reactome.org/PathwayBrowser/#/R-CEL-354073 Autophosphorylation of PTK2 at Y397 IEA Caenorhabditis elegans 18420 R-CEL-354087 https://reactome.org/PathwayBrowser/#/R-CEL-354087 Recruitment of GRB2 to p-PTK2 IEA Caenorhabditis elegans 18420 R-CEL-354124 https://reactome.org/PathwayBrowser/#/R-CEL-354124 Phosphorylation of pPTK2 by SRC IEA Caenorhabditis elegans 18420 R-CEL-354149 https://reactome.org/PathwayBrowser/#/R-CEL-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Caenorhabditis elegans 18420 R-CEL-354165 https://reactome.org/PathwayBrowser/#/R-CEL-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Caenorhabditis elegans 18420 R-CEL-377640 https://reactome.org/PathwayBrowser/#/R-CEL-377640 Autophosphorylation of SRC IEA Caenorhabditis elegans 18420 R-CEL-377641 https://reactome.org/PathwayBrowser/#/R-CEL-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Caenorhabditis elegans 18420 R-CEL-377644 https://reactome.org/PathwayBrowser/#/R-CEL-377644 Release of CSK from SRC IEA Caenorhabditis elegans 18420 R-CEL-3780994 https://reactome.org/PathwayBrowser/#/R-CEL-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Caenorhabditis elegans 18420 R-CEL-3780997 https://reactome.org/PathwayBrowser/#/R-CEL-3780997 PPP1R3C binds to glycogen:GYG2:GYS2 IEA Caenorhabditis elegans 18420 R-CEL-3781011 https://reactome.org/PathwayBrowser/#/R-CEL-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Caenorhabditis elegans 18420 R-CEL-3781018 https://reactome.org/PathwayBrowser/#/R-CEL-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Caenorhabditis elegans 18420 R-CEL-3781023 https://reactome.org/PathwayBrowser/#/R-CEL-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Caenorhabditis elegans 18420 R-CEL-3781024 https://reactome.org/PathwayBrowser/#/R-CEL-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Caenorhabditis elegans 18420 R-CEL-3858495 https://reactome.org/PathwayBrowser/#/R-CEL-3858495 DAAM1 recruits GTP-bound RHOA IEA Caenorhabditis elegans 18420 R-CEL-389611 https://reactome.org/PathwayBrowser/#/R-CEL-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Caenorhabditis elegans 18420 R-CEL-392064 https://reactome.org/PathwayBrowser/#/R-CEL-392064 G alpha (z) inhibits adenylate cyclase IEA Caenorhabditis elegans 18420 R-CEL-426223 https://reactome.org/PathwayBrowser/#/R-CEL-426223 Cation influx mediated by TRPC3/6/7 IEA Caenorhabditis elegans 18420 R-CEL-429415 https://reactome.org/PathwayBrowser/#/R-CEL-429415 SYK binds to integrin alphaIIb beta3 IEA Caenorhabditis elegans 18420 R-CEL-429441 https://reactome.org/PathwayBrowser/#/R-CEL-429441 SYK activation by SRC IEA Caenorhabditis elegans 18420 R-CEL-442661 https://reactome.org/PathwayBrowser/#/R-CEL-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol IEA Caenorhabditis elegans 18420 R-CEL-449937 https://reactome.org/PathwayBrowser/#/R-CEL-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Caenorhabditis elegans 18420 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 18420 R-CEL-5218804 https://reactome.org/PathwayBrowser/#/R-CEL-5218804 p38 MAPK activation by VEGFR IEA Caenorhabditis elegans 18420 R-CEL-5228992 https://reactome.org/PathwayBrowser/#/R-CEL-5228992 ROCK1,ROCK2 are activated IEA Caenorhabditis elegans 18420 R-CEL-5336453 https://reactome.org/PathwayBrowser/#/R-CEL-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Caenorhabditis elegans 18420 R-CEL-5339528 https://reactome.org/PathwayBrowser/#/R-CEL-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Caenorhabditis elegans 18420 R-CEL-5339538 https://reactome.org/PathwayBrowser/#/R-CEL-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Caenorhabditis elegans 18420 R-CEL-5610727 https://reactome.org/PathwayBrowser/#/R-CEL-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Caenorhabditis elegans 18420 R-CEL-5655892 https://reactome.org/PathwayBrowser/#/R-CEL-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Caenorhabditis elegans 18420 R-CEL-5656148 https://reactome.org/PathwayBrowser/#/R-CEL-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Caenorhabditis elegans 18420 R-CEL-5672972 https://reactome.org/PathwayBrowser/#/R-CEL-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Caenorhabditis elegans 18420 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 18420 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 18420 R-CEL-5672980 https://reactome.org/PathwayBrowser/#/R-CEL-5672980 Dissociation of RAS:RAF complex IEA Caenorhabditis elegans 18420 R-CEL-5694018 https://reactome.org/PathwayBrowser/#/R-CEL-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Caenorhabditis elegans 18420 R-CEL-5696021 https://reactome.org/PathwayBrowser/#/R-CEL-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Caenorhabditis elegans 18420 R-CEL-5696074 https://reactome.org/PathwayBrowser/#/R-CEL-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Caenorhabditis elegans 18420 R-CEL-6787329 https://reactome.org/PathwayBrowser/#/R-CEL-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Caenorhabditis elegans 18420 R-CEL-6788295 https://reactome.org/PathwayBrowser/#/R-CEL-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Caenorhabditis elegans 18420 R-CEL-6788597 https://reactome.org/PathwayBrowser/#/R-CEL-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Caenorhabditis elegans 18420 R-CEL-6788912 https://reactome.org/PathwayBrowser/#/R-CEL-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Caenorhabditis elegans 18420 R-CEL-70349 https://reactome.org/PathwayBrowser/#/R-CEL-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 18420 R-CEL-70479 https://reactome.org/PathwayBrowser/#/R-CEL-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Caenorhabditis elegans 18420 R-CEL-70486 https://reactome.org/PathwayBrowser/#/R-CEL-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Caenorhabditis elegans 18420 R-CEL-70494 https://reactome.org/PathwayBrowser/#/R-CEL-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Caenorhabditis elegans 18420 R-CEL-70997 https://reactome.org/PathwayBrowser/#/R-CEL-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Caenorhabditis elegans 18420 R-CEL-71037 https://reactome.org/PathwayBrowser/#/R-CEL-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 18420 R-CEL-71181 https://reactome.org/PathwayBrowser/#/R-CEL-71181 FAH cleaves 4FAA IEA Caenorhabditis elegans 18420 R-CEL-71324 https://reactome.org/PathwayBrowser/#/R-CEL-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 18420 R-CEL-71335 https://reactome.org/PathwayBrowser/#/R-CEL-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Caenorhabditis elegans 18420 R-CEL-71401 https://reactome.org/PathwayBrowser/#/R-CEL-71401 OGDH dimer decarboxylates 2-OG IEA Caenorhabditis elegans 18420 R-CEL-71660 https://reactome.org/PathwayBrowser/#/R-CEL-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Caenorhabditis elegans 18420 R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 18420 R-CEL-71732 https://reactome.org/PathwayBrowser/#/R-CEL-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Caenorhabditis elegans 18420 R-CEL-71775 https://reactome.org/PathwayBrowser/#/R-CEL-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Caenorhabditis elegans 18420 R-CEL-71850 https://reactome.org/PathwayBrowser/#/R-CEL-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Caenorhabditis elegans 18420 R-CEL-73605 https://reactome.org/PathwayBrowser/#/R-CEL-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Caenorhabditis elegans 18420 R-CEL-74215 https://reactome.org/PathwayBrowser/#/R-CEL-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Caenorhabditis elegans 18420 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 18420 R-CEL-74948 https://reactome.org/PathwayBrowser/#/R-CEL-74948 PP2A dephosphorylates p-RHO to RHO IEA Caenorhabditis elegans 18420 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 18420 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 18420 R-CEL-8939959 https://reactome.org/PathwayBrowser/#/R-CEL-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Caenorhabditis elegans 18420 R-CEL-8953499 https://reactome.org/PathwayBrowser/#/R-CEL-8953499 IMPAD1 hydrolyses PAP to AMP IEA Caenorhabditis elegans 18420 R-CEL-8955760 https://reactome.org/PathwayBrowser/#/R-CEL-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Caenorhabditis elegans 18420 R-CEL-8982667 https://reactome.org/PathwayBrowser/#/R-CEL-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Caenorhabditis elegans 18420 R-CEL-9012016 https://reactome.org/PathwayBrowser/#/R-CEL-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Caenorhabditis elegans 18420 R-CEL-9012036 https://reactome.org/PathwayBrowser/#/R-CEL-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 18420 R-CEL-9012268 https://reactome.org/PathwayBrowser/#/R-CEL-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 18420 R-CEL-9012349 https://reactome.org/PathwayBrowser/#/R-CEL-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 18420 R-CEL-9014741 https://reactome.org/PathwayBrowser/#/R-CEL-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Caenorhabditis elegans 18420 R-CEL-9014766 https://reactome.org/PathwayBrowser/#/R-CEL-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Caenorhabditis elegans 18420 R-CEL-936883 https://reactome.org/PathwayBrowser/#/R-CEL-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Caenorhabditis elegans 18420 R-CEL-947531 https://reactome.org/PathwayBrowser/#/R-CEL-947531 Molybdenum ion transfer onto molybdopterin IEA Caenorhabditis elegans 18420 R-CEL-9638125 https://reactome.org/PathwayBrowser/#/R-CEL-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Caenorhabditis elegans 18420 R-CEL-9638127 https://reactome.org/PathwayBrowser/#/R-CEL-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Caenorhabditis elegans 18420 R-CEL-9657599 https://reactome.org/PathwayBrowser/#/R-CEL-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Caenorhabditis elegans 18420 R-CEL-9657603 https://reactome.org/PathwayBrowser/#/R-CEL-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Caenorhabditis elegans 18420 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 18420 R-CEL-9657608 https://reactome.org/PathwayBrowser/#/R-CEL-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Caenorhabditis elegans 18420 R-CEL-9717841 https://reactome.org/PathwayBrowser/#/R-CEL-9717841 holo-FDPS dimer binds NBPs IEA Caenorhabditis elegans 18420 R-CEL-9748951 https://reactome.org/PathwayBrowser/#/R-CEL-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Caenorhabditis elegans 18420 R-CEL-9754916 https://reactome.org/PathwayBrowser/#/R-CEL-9754916 NT5C2 tetramer phosphorylates RBV IEA Caenorhabditis elegans 18420 R-CEL-9754974 https://reactome.org/PathwayBrowser/#/R-CEL-9754974 ADK phosphorylates RBV IEA Caenorhabditis elegans 18420 R-CEL-9755078 https://reactome.org/PathwayBrowser/#/R-CEL-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Caenorhabditis elegans 18420 R-CEL-9770141 https://reactome.org/PathwayBrowser/#/R-CEL-9770141 Formation of the Spliceosomal C* complex IEA Caenorhabditis elegans 18420 R-CEL-9770236 https://reactome.org/PathwayBrowser/#/R-CEL-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Caenorhabditis elegans 18420 R-CEL-977324 https://reactome.org/PathwayBrowser/#/R-CEL-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Caenorhabditis elegans 18420 R-CEL-983153 https://reactome.org/PathwayBrowser/#/R-CEL-983153 E1 mediated ubiquitin activation IEA Caenorhabditis elegans 18420 R-CEL-9853499 https://reactome.org/PathwayBrowser/#/R-CEL-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 18420 R-CEL-9853512 https://reactome.org/PathwayBrowser/#/R-CEL-9853512 DLST transfers succinyl to CoA IEA Caenorhabditis elegans 18420 R-CEL-9861616 https://reactome.org/PathwayBrowser/#/R-CEL-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 18420 R-CEL-9861631 https://reactome.org/PathwayBrowser/#/R-CEL-9861631 ME1 tetramerizes IEA Caenorhabditis elegans 18420 R-CEL-9861660 https://reactome.org/PathwayBrowser/#/R-CEL-9861660 ME1 tetramer decarboxylates OA to PYR IEA Caenorhabditis elegans 18420 R-CEL-9861667 https://reactome.org/PathwayBrowser/#/R-CEL-9861667 DLAT trimer transfers acetyl to CoA IEA Caenorhabditis elegans 18420 R-CEL-9861734 https://reactome.org/PathwayBrowser/#/R-CEL-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Caenorhabditis elegans 18420 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 18420 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 18420 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 18420 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 18420 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 18420 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 18420 R-CFA-109624 https://reactome.org/PathwayBrowser/#/R-CFA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Canis familiaris 18420 R-CFA-109671 https://reactome.org/PathwayBrowser/#/R-CFA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Canis familiaris 18420 R-CFA-111215 https://reactome.org/PathwayBrowser/#/R-CFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Canis familiaris 18420 R-CFA-111524 https://reactome.org/PathwayBrowser/#/R-CFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Canis familiaris 18420 R-CFA-111930 https://reactome.org/PathwayBrowser/#/R-CFA-111930 Adenylate cyclase produces cAMP IEA Canis familiaris 18420 R-CFA-1237129 https://reactome.org/PathwayBrowser/#/R-CFA-1237129 Acireductone is created IEA Canis familiaris 18420 R-CFA-1482961 https://reactome.org/PathwayBrowser/#/R-CFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Canis familiaris 18420 R-CFA-1482962 https://reactome.org/PathwayBrowser/#/R-CFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Canis familiaris 18420 R-CFA-1482973 https://reactome.org/PathwayBrowser/#/R-CFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Canis familiaris 18420 R-CFA-1482976 https://reactome.org/PathwayBrowser/#/R-CFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Canis familiaris 18420 R-CFA-1483096 https://reactome.org/PathwayBrowser/#/R-CFA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Canis familiaris 18420 R-CFA-1483121 https://reactome.org/PathwayBrowser/#/R-CFA-1483121 PA is converted to CDP-DAG by CDS1 IEA Canis familiaris 18420 R-CFA-1483159 https://reactome.org/PathwayBrowser/#/R-CFA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Canis familiaris 18420 R-CFA-1483203 https://reactome.org/PathwayBrowser/#/R-CFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Canis familiaris 18420 R-CFA-1606273 https://reactome.org/PathwayBrowser/#/R-CFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Canis familiaris 18420 R-CFA-1606288 https://reactome.org/PathwayBrowser/#/R-CFA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Canis familiaris 18420 R-CFA-163741 https://reactome.org/PathwayBrowser/#/R-CFA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Canis familiaris 18420 R-CFA-163751 https://reactome.org/PathwayBrowser/#/R-CFA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Canis familiaris 18420 R-CFA-1675928 https://reactome.org/PathwayBrowser/#/R-CFA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Canis familiaris 18420 R-CFA-1675939 https://reactome.org/PathwayBrowser/#/R-CFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Canis familiaris 18420 R-CFA-1675961 https://reactome.org/PathwayBrowser/#/R-CFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Canis familiaris 18420 R-CFA-1676024 https://reactome.org/PathwayBrowser/#/R-CFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Canis familiaris 18420 R-CFA-1676109 https://reactome.org/PathwayBrowser/#/R-CFA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Canis familiaris 18420 R-CFA-1676206 https://reactome.org/PathwayBrowser/#/R-CFA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Canis familiaris 18420 R-CFA-170666 https://reactome.org/PathwayBrowser/#/R-CFA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Canis familiaris 18420 R-CFA-170671 https://reactome.org/PathwayBrowser/#/R-CFA-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Canis familiaris 18420 R-CFA-170672 https://reactome.org/PathwayBrowser/#/R-CFA-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Canis familiaris 18420 R-CFA-170674 https://reactome.org/PathwayBrowser/#/R-CFA-170674 Dissociation of the Gi alpha:G olf complex IEA Canis familiaris 18420 R-CFA-170676 https://reactome.org/PathwayBrowser/#/R-CFA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Canis familiaris 18420 R-CFA-170677 https://reactome.org/PathwayBrowser/#/R-CFA-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Canis familiaris 18420 R-CFA-170685 https://reactome.org/PathwayBrowser/#/R-CFA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Canis familiaris 18420 R-CFA-170686 https://reactome.org/PathwayBrowser/#/R-CFA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Canis familiaris 18420 R-CFA-174391 https://reactome.org/PathwayBrowser/#/R-CFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Canis familiaris 18420 R-CFA-174394 https://reactome.org/PathwayBrowser/#/R-CFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Canis familiaris 18420 R-CFA-1855154 https://reactome.org/PathwayBrowser/#/R-CFA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 18420 R-CFA-1855159 https://reactome.org/PathwayBrowser/#/R-CFA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Canis familiaris 18420 R-CFA-1855162 https://reactome.org/PathwayBrowser/#/R-CFA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Canis familiaris 18420 R-CFA-1855165 https://reactome.org/PathwayBrowser/#/R-CFA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 18420 R-CFA-1855166 https://reactome.org/PathwayBrowser/#/R-CFA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Canis familiaris 18420 R-CFA-1855169 https://reactome.org/PathwayBrowser/#/R-CFA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 18420 R-CFA-1855171 https://reactome.org/PathwayBrowser/#/R-CFA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Canis familiaris 18420 R-CFA-1855172 https://reactome.org/PathwayBrowser/#/R-CFA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Canis familiaris 18420 R-CFA-1855197 https://reactome.org/PathwayBrowser/#/R-CFA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 18420 R-CFA-1855198 https://reactome.org/PathwayBrowser/#/R-CFA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 18420 R-CFA-1855205 https://reactome.org/PathwayBrowser/#/R-CFA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Canis familiaris 18420 R-CFA-1855208 https://reactome.org/PathwayBrowser/#/R-CFA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Canis familiaris 18420 R-CFA-1855210 https://reactome.org/PathwayBrowser/#/R-CFA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 18420 R-CFA-1855211 https://reactome.org/PathwayBrowser/#/R-CFA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 18420 R-CFA-1855218 https://reactome.org/PathwayBrowser/#/R-CFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Canis familiaris 18420 R-CFA-1855219 https://reactome.org/PathwayBrowser/#/R-CFA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 18420 R-CFA-1855232 https://reactome.org/PathwayBrowser/#/R-CFA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Canis familiaris 18420 R-CFA-191303 https://reactome.org/PathwayBrowser/#/R-CFA-191303 FDPS dimer transfers IPPP to GPP IEA Canis familiaris 18420 R-CFA-191322 https://reactome.org/PathwayBrowser/#/R-CFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Canis familiaris 18420 R-CFA-191382 https://reactome.org/PathwayBrowser/#/R-CFA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Canis familiaris 18420 R-CFA-191402 https://reactome.org/PathwayBrowser/#/R-CFA-191402 Reduction of presqualene diphosphate to form squalene IEA Canis familiaris 18420 R-CFA-191405 https://reactome.org/PathwayBrowser/#/R-CFA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Canis familiaris 18420 R-CFA-196761 https://reactome.org/PathwayBrowser/#/R-CFA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Canis familiaris 18420 R-CFA-196964 https://reactome.org/PathwayBrowser/#/R-CFA-196964 RFK:Mg2+ phosphorylates RIB IEA Canis familiaris 18420 R-CFA-197186 https://reactome.org/PathwayBrowser/#/R-CFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Canis familiaris 18420 R-CFA-197235 https://reactome.org/PathwayBrowser/#/R-CFA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 18420 R-CFA-200474 https://reactome.org/PathwayBrowser/#/R-CFA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 18420 R-CFA-2023971 https://reactome.org/PathwayBrowser/#/R-CFA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 18420 R-CFA-2023973 https://reactome.org/PathwayBrowser/#/R-CFA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 18420 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 18420 R-CFA-204169 https://reactome.org/PathwayBrowser/#/R-CFA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Canis familiaris 18420 R-CFA-2046085 https://reactome.org/PathwayBrowser/#/R-CFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Canis familiaris 18420 R-CFA-2046098 https://reactome.org/PathwayBrowser/#/R-CFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Canis familiaris 18420 R-CFA-216043 https://reactome.org/PathwayBrowser/#/R-CFA-216043 Collagen type II binds integrin alpha10beta1 IEA Canis familiaris 18420 R-CFA-216045 https://reactome.org/PathwayBrowser/#/R-CFA-216045 Collagen type I binds integrin alpha11beta1 IEA Canis familiaris 18420 R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Canis familiaris 18420 R-CFA-2162066 https://reactome.org/PathwayBrowser/#/R-CFA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Canis familiaris 18420 R-CFA-2162253 https://reactome.org/PathwayBrowser/#/R-CFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Canis familiaris 18420 R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 18420 R-CFA-2393939 https://reactome.org/PathwayBrowser/#/R-CFA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 18420 R-CFA-2393954 https://reactome.org/PathwayBrowser/#/R-CFA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 18420 R-CFA-2395818 https://reactome.org/PathwayBrowser/#/R-CFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Canis familiaris 18420 R-CFA-2395849 https://reactome.org/PathwayBrowser/#/R-CFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 18420 R-CFA-2395872 https://reactome.org/PathwayBrowser/#/R-CFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Canis familiaris 18420 R-CFA-2408551 https://reactome.org/PathwayBrowser/#/R-CFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Canis familiaris 18420 R-CFA-2509793 https://reactome.org/PathwayBrowser/#/R-CFA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Canis familiaris 18420 R-CFA-2509816 https://reactome.org/PathwayBrowser/#/R-CFA-2509816 NUDT16 hydrolyses IDP to IMP IEA Canis familiaris 18420 R-CFA-2509827 https://reactome.org/PathwayBrowser/#/R-CFA-2509827 ITPA hydrolyses ITP to IMP IEA Canis familiaris 18420 R-CFA-2509831 https://reactome.org/PathwayBrowser/#/R-CFA-2509831 ITPA hydrolyses XTP to XMP IEA Canis familiaris 18420 R-CFA-2509838 https://reactome.org/PathwayBrowser/#/R-CFA-2509838 ITPA hydrolyses dITP to dIMP IEA Canis familiaris 18420 R-CFA-265682 https://reactome.org/PathwayBrowser/#/R-CFA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Canis familiaris 18420 R-CFA-3322001 https://reactome.org/PathwayBrowser/#/R-CFA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Canis familiaris 18420 R-CFA-3322003 https://reactome.org/PathwayBrowser/#/R-CFA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Canis familiaris 18420 R-CFA-3322005 https://reactome.org/PathwayBrowser/#/R-CFA-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Canis familiaris 18420 R-CFA-3322009 https://reactome.org/PathwayBrowser/#/R-CFA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Canis familiaris 18420 R-CFA-3322014 https://reactome.org/PathwayBrowser/#/R-CFA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Canis familiaris 18420 R-CFA-3322016 https://reactome.org/PathwayBrowser/#/R-CFA-3322016 GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a IEA Canis familiaris 18420 R-CFA-3322019 https://reactome.org/PathwayBrowser/#/R-CFA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Canis familiaris 18420 R-CFA-3322025 https://reactome.org/PathwayBrowser/#/R-CFA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Canis familiaris 18420 R-CFA-3322041 https://reactome.org/PathwayBrowser/#/R-CFA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Canis familiaris 18420 R-CFA-3322057 https://reactome.org/PathwayBrowser/#/R-CFA-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Canis familiaris 18420 R-CFA-354066 https://reactome.org/PathwayBrowser/#/R-CFA-354066 Translocation of PTK2 to Focal complexes IEA Canis familiaris 18420 R-CFA-354073 https://reactome.org/PathwayBrowser/#/R-CFA-354073 Autophosphorylation of PTK2 at Y397 IEA Canis familiaris 18420 R-CFA-354087 https://reactome.org/PathwayBrowser/#/R-CFA-354087 Recruitment of GRB2 to p-PTK2 IEA Canis familiaris 18420 R-CFA-354124 https://reactome.org/PathwayBrowser/#/R-CFA-354124 Phosphorylation of pPTK2 by SRC IEA Canis familiaris 18420 R-CFA-354149 https://reactome.org/PathwayBrowser/#/R-CFA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Canis familiaris 18420 R-CFA-354165 https://reactome.org/PathwayBrowser/#/R-CFA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Canis familiaris 18420 R-CFA-372693 https://reactome.org/PathwayBrowser/#/R-CFA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Canis familiaris 18420 R-CFA-372697 https://reactome.org/PathwayBrowser/#/R-CFA-372697 Crk binding to p130cas IEA Canis familiaris 18420 R-CFA-372705 https://reactome.org/PathwayBrowser/#/R-CFA-372705 Recruitment of BCAR1 to PTK2 complex IEA Canis familiaris 18420 R-CFA-377640 https://reactome.org/PathwayBrowser/#/R-CFA-377640 Autophosphorylation of SRC IEA Canis familiaris 18420 R-CFA-377641 https://reactome.org/PathwayBrowser/#/R-CFA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Canis familiaris 18420 R-CFA-377643 https://reactome.org/PathwayBrowser/#/R-CFA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Canis familiaris 18420 R-CFA-377644 https://reactome.org/PathwayBrowser/#/R-CFA-377644 Release of CSK from SRC IEA Canis familiaris 18420 R-CFA-3780994 https://reactome.org/PathwayBrowser/#/R-CFA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Canis familiaris 18420 R-CFA-3780997 https://reactome.org/PathwayBrowser/#/R-CFA-3780997 PPP1R3C binds to glycogen:GYG2:GYS2 IEA Canis familiaris 18420 R-CFA-3781011 https://reactome.org/PathwayBrowser/#/R-CFA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Canis familiaris 18420 R-CFA-3781018 https://reactome.org/PathwayBrowser/#/R-CFA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Canis familiaris 18420 R-CFA-3781023 https://reactome.org/PathwayBrowser/#/R-CFA-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Canis familiaris 18420 R-CFA-3781024 https://reactome.org/PathwayBrowser/#/R-CFA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Canis familiaris 18420 R-CFA-3858495 https://reactome.org/PathwayBrowser/#/R-CFA-3858495 DAAM1 recruits GTP-bound RHOA IEA Canis familiaris 18420 R-CFA-389611 https://reactome.org/PathwayBrowser/#/R-CFA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Canis familiaris 18420 R-CFA-392064 https://reactome.org/PathwayBrowser/#/R-CFA-392064 G alpha (z) inhibits adenylate cyclase IEA Canis familiaris 18420 R-CFA-4084989 https://reactome.org/PathwayBrowser/#/R-CFA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Canis familiaris 18420 R-CFA-421879 https://reactome.org/PathwayBrowser/#/R-CFA-421879 Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate TAS Canis familiaris 18420 R-CFA-426223 https://reactome.org/PathwayBrowser/#/R-CFA-426223 Cation influx mediated by TRPC3/6/7 IEA Canis familiaris 18420 R-CFA-429415 https://reactome.org/PathwayBrowser/#/R-CFA-429415 SYK binds to integrin alphaIIb beta3 IEA Canis familiaris 18420 R-CFA-429441 https://reactome.org/PathwayBrowser/#/R-CFA-429441 SYK activation by SRC IEA Canis familiaris 18420 R-CFA-442661 https://reactome.org/PathwayBrowser/#/R-CFA-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol IEA Canis familiaris 18420 R-CFA-449937 https://reactome.org/PathwayBrowser/#/R-CFA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Canis familiaris 18420 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 18420 R-CFA-5218804 https://reactome.org/PathwayBrowser/#/R-CFA-5218804 p38 MAPK activation by VEGFR IEA Canis familiaris 18420 R-CFA-5218826 https://reactome.org/PathwayBrowser/#/R-CFA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Canis familiaris 18420 R-CFA-5228992 https://reactome.org/PathwayBrowser/#/R-CFA-5228992 ROCK1,ROCK2 are activated IEA Canis familiaris 18420 R-CFA-5336453 https://reactome.org/PathwayBrowser/#/R-CFA-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Canis familiaris 18420 R-CFA-5336466 https://reactome.org/PathwayBrowser/#/R-CFA-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Canis familiaris 18420 R-CFA-5339528 https://reactome.org/PathwayBrowser/#/R-CFA-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Canis familiaris 18420 R-CFA-5339538 https://reactome.org/PathwayBrowser/#/R-CFA-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Canis familiaris 18420 R-CFA-5603114 https://reactome.org/PathwayBrowser/#/R-CFA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Canis familiaris 18420 R-CFA-5610727 https://reactome.org/PathwayBrowser/#/R-CFA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Canis familiaris 18420 R-CFA-5655835 https://reactome.org/PathwayBrowser/#/R-CFA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Canis familiaris 18420 R-CFA-5655892 https://reactome.org/PathwayBrowser/#/R-CFA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Canis familiaris 18420 R-CFA-5655965 https://reactome.org/PathwayBrowser/#/R-CFA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Canis familiaris 18420 R-CFA-5656105 https://reactome.org/PathwayBrowser/#/R-CFA-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Canis familiaris 18420 R-CFA-5656148 https://reactome.org/PathwayBrowser/#/R-CFA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Canis familiaris 18420 R-CFA-5656158 https://reactome.org/PathwayBrowser/#/R-CFA-5656158 POLZ elongates POLI-incorporated dNMP IEA Canis familiaris 18420 R-CFA-5672972 https://reactome.org/PathwayBrowser/#/R-CFA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Canis familiaris 18420 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 18420 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 18420 R-CFA-5672980 https://reactome.org/PathwayBrowser/#/R-CFA-5672980 Dissociation of RAS:RAF complex IEA Canis familiaris 18420 R-CFA-5694018 https://reactome.org/PathwayBrowser/#/R-CFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Canis familiaris 18420 R-CFA-5696021 https://reactome.org/PathwayBrowser/#/R-CFA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Canis familiaris 18420 R-CFA-5696074 https://reactome.org/PathwayBrowser/#/R-CFA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Canis familiaris 18420 R-CFA-6787329 https://reactome.org/PathwayBrowser/#/R-CFA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Canis familiaris 18420 R-CFA-6788295 https://reactome.org/PathwayBrowser/#/R-CFA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Canis familiaris 18420 R-CFA-6788597 https://reactome.org/PathwayBrowser/#/R-CFA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Canis familiaris 18420 R-CFA-6788912 https://reactome.org/PathwayBrowser/#/R-CFA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Canis familiaris 18420 R-CFA-70349 https://reactome.org/PathwayBrowser/#/R-CFA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Canis familiaris 18420 R-CFA-70479 https://reactome.org/PathwayBrowser/#/R-CFA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Canis familiaris 18420 R-CFA-70486 https://reactome.org/PathwayBrowser/#/R-CFA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Canis familiaris 18420 R-CFA-70494 https://reactome.org/PathwayBrowser/#/R-CFA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Canis familiaris 18420 R-CFA-70997 https://reactome.org/PathwayBrowser/#/R-CFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Canis familiaris 18420 R-CFA-71037 https://reactome.org/PathwayBrowser/#/R-CFA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Canis familiaris 18420 R-CFA-71181 https://reactome.org/PathwayBrowser/#/R-CFA-71181 FAH cleaves 4FAA IEA Canis familiaris 18420 R-CFA-71324 https://reactome.org/PathwayBrowser/#/R-CFA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 18420 R-CFA-71335 https://reactome.org/PathwayBrowser/#/R-CFA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Canis familiaris 18420 R-CFA-71401 https://reactome.org/PathwayBrowser/#/R-CFA-71401 OGDH dimer decarboxylates 2-OG IEA Canis familiaris 18420 R-CFA-71660 https://reactome.org/PathwayBrowser/#/R-CFA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Canis familiaris 18420 R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 18420 R-CFA-71732 https://reactome.org/PathwayBrowser/#/R-CFA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Canis familiaris 18420 R-CFA-71775 https://reactome.org/PathwayBrowser/#/R-CFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Canis familiaris 18420 R-CFA-71850 https://reactome.org/PathwayBrowser/#/R-CFA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Canis familiaris 18420 R-CFA-73598 https://reactome.org/PathwayBrowser/#/R-CFA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Canis familiaris 18420 R-CFA-73605 https://reactome.org/PathwayBrowser/#/R-CFA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Canis familiaris 18420 R-CFA-74215 https://reactome.org/PathwayBrowser/#/R-CFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Canis familiaris 18420 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 18420 R-CFA-74948 https://reactome.org/PathwayBrowser/#/R-CFA-74948 PP2A dephosphorylates p-RHO to RHO IEA Canis familiaris 18420 R-CFA-8850846 https://reactome.org/PathwayBrowser/#/R-CFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Canis familiaris 18420 R-CFA-8850854 https://reactome.org/PathwayBrowser/#/R-CFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Canis familiaris 18420 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 18420 R-CFA-8851110 https://reactome.org/PathwayBrowser/#/R-CFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Canis familiaris 18420 R-CFA-8851129 https://reactome.org/PathwayBrowser/#/R-CFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Canis familiaris 18420 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 18420 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 18420 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 18420 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 18420 R-CFA-8939959 https://reactome.org/PathwayBrowser/#/R-CFA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Canis familiaris 18420 R-CFA-8953499 https://reactome.org/PathwayBrowser/#/R-CFA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Canis familiaris 18420 R-CFA-8955760 https://reactome.org/PathwayBrowser/#/R-CFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Canis familiaris 18420 R-CFA-8982667 https://reactome.org/PathwayBrowser/#/R-CFA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Canis familiaris 18420 R-CFA-9012016 https://reactome.org/PathwayBrowser/#/R-CFA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Canis familiaris 18420 R-CFA-9012036 https://reactome.org/PathwayBrowser/#/R-CFA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Canis familiaris 18420 R-CFA-9012268 https://reactome.org/PathwayBrowser/#/R-CFA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Canis familiaris 18420 R-CFA-9012349 https://reactome.org/PathwayBrowser/#/R-CFA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Canis familiaris 18420 R-CFA-9014741 https://reactome.org/PathwayBrowser/#/R-CFA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Canis familiaris 18420 R-CFA-9014766 https://reactome.org/PathwayBrowser/#/R-CFA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Canis familiaris 18420 R-CFA-9024993 https://reactome.org/PathwayBrowser/#/R-CFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Canis familiaris 18420 R-CFA-936883 https://reactome.org/PathwayBrowser/#/R-CFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Canis familiaris 18420 R-CFA-947531 https://reactome.org/PathwayBrowser/#/R-CFA-947531 Molybdenum ion transfer onto molybdopterin IEA Canis familiaris 18420 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 18420 R-CFA-9621179 https://reactome.org/PathwayBrowser/#/R-CFA-9621179 Cinaciguat binds sGC:NO IEA Canis familiaris 18420 R-CFA-965067 https://reactome.org/PathwayBrowser/#/R-CFA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Canis familiaris 18420 R-CFA-9650858 https://reactome.org/PathwayBrowser/#/R-CFA-9650858 Meglitinides bind ABCC8 IEA Canis familiaris 18420 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 18420 R-CFA-9657599 https://reactome.org/PathwayBrowser/#/R-CFA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Canis familiaris 18420 R-CFA-9657603 https://reactome.org/PathwayBrowser/#/R-CFA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Canis familiaris 18420 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 18420 R-CFA-9657608 https://reactome.org/PathwayBrowser/#/R-CFA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Canis familiaris 18420 R-CFA-9717830 https://reactome.org/PathwayBrowser/#/R-CFA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Canis familiaris 18420 R-CFA-9717834 https://reactome.org/PathwayBrowser/#/R-CFA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Canis familiaris 18420 R-CFA-9717841 https://reactome.org/PathwayBrowser/#/R-CFA-9717841 holo-FDPS dimer binds NBPs IEA Canis familiaris 18420 R-CFA-9731228 https://reactome.org/PathwayBrowser/#/R-CFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Canis familiaris 18420 R-CFA-9731590 https://reactome.org/PathwayBrowser/#/R-CFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Canis familiaris 18420 R-CFA-9731613 https://reactome.org/PathwayBrowser/#/R-CFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Canis familiaris 18420 R-CFA-9731632 https://reactome.org/PathwayBrowser/#/R-CFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Canis familiaris 18420 R-CFA-9748951 https://reactome.org/PathwayBrowser/#/R-CFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Canis familiaris 18420 R-CFA-9754916 https://reactome.org/PathwayBrowser/#/R-CFA-9754916 NT5C2 tetramer phosphorylates RBV IEA Canis familiaris 18420 R-CFA-9754974 https://reactome.org/PathwayBrowser/#/R-CFA-9754974 ADK phosphorylates RBV IEA Canis familiaris 18420 R-CFA-9755078 https://reactome.org/PathwayBrowser/#/R-CFA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Canis familiaris 18420 R-CFA-9770141 https://reactome.org/PathwayBrowser/#/R-CFA-9770141 Formation of the Spliceosomal C* complex IEA Canis familiaris 18420 R-CFA-9770236 https://reactome.org/PathwayBrowser/#/R-CFA-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Canis familiaris 18420 R-CFA-977324 https://reactome.org/PathwayBrowser/#/R-CFA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Canis familiaris 18420 R-CFA-983153 https://reactome.org/PathwayBrowser/#/R-CFA-983153 E1 mediated ubiquitin activation IEA Canis familiaris 18420 R-CFA-9853499 https://reactome.org/PathwayBrowser/#/R-CFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 18420 R-CFA-9853512 https://reactome.org/PathwayBrowser/#/R-CFA-9853512 DLST transfers succinyl to CoA IEA Canis familiaris 18420 R-CFA-9861616 https://reactome.org/PathwayBrowser/#/R-CFA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 18420 R-CFA-9861631 https://reactome.org/PathwayBrowser/#/R-CFA-9861631 ME1 tetramerizes IEA Canis familiaris 18420 R-CFA-9861642 https://reactome.org/PathwayBrowser/#/R-CFA-9861642 NEK1 phosphorylates ME1 IEA Canis familiaris 18420 R-CFA-9861660 https://reactome.org/PathwayBrowser/#/R-CFA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Canis familiaris 18420 R-CFA-9861667 https://reactome.org/PathwayBrowser/#/R-CFA-9861667 DLAT trimer transfers acetyl to CoA IEA Canis familiaris 18420 R-CFA-9861734 https://reactome.org/PathwayBrowser/#/R-CFA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Canis familiaris 18420 R-DDI-109624 https://reactome.org/PathwayBrowser/#/R-DDI-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Dictyostelium discoideum 18420 R-DDI-111215 https://reactome.org/PathwayBrowser/#/R-DDI-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Dictyostelium discoideum 18420 R-DDI-111524 https://reactome.org/PathwayBrowser/#/R-DDI-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Dictyostelium discoideum 18420 R-DDI-111930 https://reactome.org/PathwayBrowser/#/R-DDI-111930 Adenylate cyclase produces cAMP IEA Dictyostelium discoideum 18420 R-DDI-1237129 https://reactome.org/PathwayBrowser/#/R-DDI-1237129 Acireductone is created IEA Dictyostelium discoideum 18420 R-DDI-1482961 https://reactome.org/PathwayBrowser/#/R-DDI-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Dictyostelium discoideum 18420 R-DDI-1482962 https://reactome.org/PathwayBrowser/#/R-DDI-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Dictyostelium discoideum 18420 R-DDI-1482973 https://reactome.org/PathwayBrowser/#/R-DDI-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Dictyostelium discoideum 18420 R-DDI-1482976 https://reactome.org/PathwayBrowser/#/R-DDI-1482976 CDP-DAG is converted to PI by CDIPT IEA Dictyostelium discoideum 18420 R-DDI-1483121 https://reactome.org/PathwayBrowser/#/R-DDI-1483121 PA is converted to CDP-DAG by CDS1 IEA Dictyostelium discoideum 18420 R-DDI-1483203 https://reactome.org/PathwayBrowser/#/R-DDI-1483203 PA is dephosphorylated to DAG by LPIN IEA Dictyostelium discoideum 18420 R-DDI-1606273 https://reactome.org/PathwayBrowser/#/R-DDI-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Dictyostelium discoideum 18420 R-DDI-1675928 https://reactome.org/PathwayBrowser/#/R-DDI-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Dictyostelium discoideum 18420 R-DDI-1675939 https://reactome.org/PathwayBrowser/#/R-DDI-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Dictyostelium discoideum 18420 R-DDI-1675961 https://reactome.org/PathwayBrowser/#/R-DDI-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Dictyostelium discoideum 18420 R-DDI-1676024 https://reactome.org/PathwayBrowser/#/R-DDI-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Dictyostelium discoideum 18420 R-DDI-1676109 https://reactome.org/PathwayBrowser/#/R-DDI-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Dictyostelium discoideum 18420 R-DDI-1676206 https://reactome.org/PathwayBrowser/#/R-DDI-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Dictyostelium discoideum 18420 R-DDI-170666 https://reactome.org/PathwayBrowser/#/R-DDI-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Dictyostelium discoideum 18420 R-DDI-170671 https://reactome.org/PathwayBrowser/#/R-DDI-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Dictyostelium discoideum 18420 R-DDI-170672 https://reactome.org/PathwayBrowser/#/R-DDI-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Dictyostelium discoideum 18420 R-DDI-170674 https://reactome.org/PathwayBrowser/#/R-DDI-170674 Dissociation of the Gi alpha:G olf complex IEA Dictyostelium discoideum 18420 R-DDI-170676 https://reactome.org/PathwayBrowser/#/R-DDI-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Dictyostelium discoideum 18420 R-DDI-170677 https://reactome.org/PathwayBrowser/#/R-DDI-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Dictyostelium discoideum 18420 R-DDI-170685 https://reactome.org/PathwayBrowser/#/R-DDI-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Dictyostelium discoideum 18420 R-DDI-170686 https://reactome.org/PathwayBrowser/#/R-DDI-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Dictyostelium discoideum 18420 R-DDI-174391 https://reactome.org/PathwayBrowser/#/R-DDI-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Dictyostelium discoideum 18420 R-DDI-174394 https://reactome.org/PathwayBrowser/#/R-DDI-174394 GSS:Mg2+ dimer synthesizes GSH IEA Dictyostelium discoideum 18420 R-DDI-1855154 https://reactome.org/PathwayBrowser/#/R-DDI-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855159 https://reactome.org/PathwayBrowser/#/R-DDI-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855162 https://reactome.org/PathwayBrowser/#/R-DDI-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855165 https://reactome.org/PathwayBrowser/#/R-DDI-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855166 https://reactome.org/PathwayBrowser/#/R-DDI-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855169 https://reactome.org/PathwayBrowser/#/R-DDI-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855171 https://reactome.org/PathwayBrowser/#/R-DDI-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855172 https://reactome.org/PathwayBrowser/#/R-DDI-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855197 https://reactome.org/PathwayBrowser/#/R-DDI-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855198 https://reactome.org/PathwayBrowser/#/R-DDI-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855205 https://reactome.org/PathwayBrowser/#/R-DDI-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855208 https://reactome.org/PathwayBrowser/#/R-DDI-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855210 https://reactome.org/PathwayBrowser/#/R-DDI-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855211 https://reactome.org/PathwayBrowser/#/R-DDI-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855218 https://reactome.org/PathwayBrowser/#/R-DDI-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855219 https://reactome.org/PathwayBrowser/#/R-DDI-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-1855232 https://reactome.org/PathwayBrowser/#/R-DDI-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-191303 https://reactome.org/PathwayBrowser/#/R-DDI-191303 FDPS dimer transfers IPPP to GPP IEA Dictyostelium discoideum 18420 R-DDI-191322 https://reactome.org/PathwayBrowser/#/R-DDI-191322 FDPS dimer transfers IPPP to DMAPP IEA Dictyostelium discoideum 18420 R-DDI-191382 https://reactome.org/PathwayBrowser/#/R-DDI-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Dictyostelium discoideum 18420 R-DDI-191402 https://reactome.org/PathwayBrowser/#/R-DDI-191402 Reduction of presqualene diphosphate to form squalene IEA Dictyostelium discoideum 18420 R-DDI-191405 https://reactome.org/PathwayBrowser/#/R-DDI-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Dictyostelium discoideum 18420 R-DDI-196761 https://reactome.org/PathwayBrowser/#/R-DDI-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Dictyostelium discoideum 18420 R-DDI-197186 https://reactome.org/PathwayBrowser/#/R-DDI-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Dictyostelium discoideum 18420 R-DDI-197235 https://reactome.org/PathwayBrowser/#/R-DDI-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 18420 R-DDI-200474 https://reactome.org/PathwayBrowser/#/R-DDI-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 18420 R-DDI-2023971 https://reactome.org/PathwayBrowser/#/R-DDI-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-2023973 https://reactome.org/PathwayBrowser/#/R-DDI-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 18420 R-DDI-2046085 https://reactome.org/PathwayBrowser/#/R-DDI-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Dictyostelium discoideum 18420 R-DDI-2046098 https://reactome.org/PathwayBrowser/#/R-DDI-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Dictyostelium discoideum 18420 R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Dictyostelium discoideum 18420 R-DDI-2162066 https://reactome.org/PathwayBrowser/#/R-DDI-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Dictyostelium discoideum 18420 R-DDI-2162253 https://reactome.org/PathwayBrowser/#/R-DDI-2162253 PDSS1,2 ligates FPP to IPPP IEA Dictyostelium discoideum 18420 R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 18420 R-DDI-2393939 https://reactome.org/PathwayBrowser/#/R-DDI-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Dictyostelium discoideum 18420 R-DDI-2408551 https://reactome.org/PathwayBrowser/#/R-DDI-2408551 SeMet is converted to AdoSeMet by MAT IEA Dictyostelium discoideum 18420 R-DDI-2509827 https://reactome.org/PathwayBrowser/#/R-DDI-2509827 ITPA hydrolyses ITP to IMP IEA Dictyostelium discoideum 18420 R-DDI-2509831 https://reactome.org/PathwayBrowser/#/R-DDI-2509831 ITPA hydrolyses XTP to XMP IEA Dictyostelium discoideum 18420 R-DDI-2509838 https://reactome.org/PathwayBrowser/#/R-DDI-2509838 ITPA hydrolyses dITP to dIMP IEA Dictyostelium discoideum 18420 R-DDI-3322001 https://reactome.org/PathwayBrowser/#/R-DDI-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Dictyostelium discoideum 18420 R-DDI-3322003 https://reactome.org/PathwayBrowser/#/R-DDI-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Dictyostelium discoideum 18420 R-DDI-3322005 https://reactome.org/PathwayBrowser/#/R-DDI-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Dictyostelium discoideum 18420 R-DDI-3322009 https://reactome.org/PathwayBrowser/#/R-DDI-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Dictyostelium discoideum 18420 R-DDI-3322014 https://reactome.org/PathwayBrowser/#/R-DDI-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Dictyostelium discoideum 18420 R-DDI-3322016 https://reactome.org/PathwayBrowser/#/R-DDI-3322016 GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a IEA Dictyostelium discoideum 18420 R-DDI-3322019 https://reactome.org/PathwayBrowser/#/R-DDI-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Dictyostelium discoideum 18420 R-DDI-3322025 https://reactome.org/PathwayBrowser/#/R-DDI-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Dictyostelium discoideum 18420 R-DDI-3322041 https://reactome.org/PathwayBrowser/#/R-DDI-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Dictyostelium discoideum 18420 R-DDI-3322057 https://reactome.org/PathwayBrowser/#/R-DDI-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Dictyostelium discoideum 18420 R-DDI-389611 https://reactome.org/PathwayBrowser/#/R-DDI-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Dictyostelium discoideum 18420 R-DDI-392064 https://reactome.org/PathwayBrowser/#/R-DDI-392064 G alpha (z) inhibits adenylate cyclase IEA Dictyostelium discoideum 18420 R-DDI-449937 https://reactome.org/PathwayBrowser/#/R-DDI-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Dictyostelium discoideum 18420 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 18420 R-DDI-5336466 https://reactome.org/PathwayBrowser/#/R-DDI-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Dictyostelium discoideum 18420 R-DDI-5339528 https://reactome.org/PathwayBrowser/#/R-DDI-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Dictyostelium discoideum 18420 R-DDI-5339538 https://reactome.org/PathwayBrowser/#/R-DDI-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Dictyostelium discoideum 18420 R-DDI-5603114 https://reactome.org/PathwayBrowser/#/R-DDI-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Dictyostelium discoideum 18420 R-DDI-5610727 https://reactome.org/PathwayBrowser/#/R-DDI-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Dictyostelium discoideum 18420 R-DDI-5655892 https://reactome.org/PathwayBrowser/#/R-DDI-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Dictyostelium discoideum 18420 R-DDI-5694018 https://reactome.org/PathwayBrowser/#/R-DDI-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Dictyostelium discoideum 18420 R-DDI-5696021 https://reactome.org/PathwayBrowser/#/R-DDI-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Dictyostelium discoideum 18420 R-DDI-5696074 https://reactome.org/PathwayBrowser/#/R-DDI-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Dictyostelium discoideum 18420 R-DDI-6787329 https://reactome.org/PathwayBrowser/#/R-DDI-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Dictyostelium discoideum 18420 R-DDI-6788597 https://reactome.org/PathwayBrowser/#/R-DDI-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Dictyostelium discoideum 18420 R-DDI-70349 https://reactome.org/PathwayBrowser/#/R-DDI-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 18420 R-DDI-70479 https://reactome.org/PathwayBrowser/#/R-DDI-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Dictyostelium discoideum 18420 R-DDI-70486 https://reactome.org/PathwayBrowser/#/R-DDI-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Dictyostelium discoideum 18420 R-DDI-70494 https://reactome.org/PathwayBrowser/#/R-DDI-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Dictyostelium discoideum 18420 R-DDI-70997 https://reactome.org/PathwayBrowser/#/R-DDI-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Dictyostelium discoideum 18420 R-DDI-71037 https://reactome.org/PathwayBrowser/#/R-DDI-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 18420 R-DDI-71181 https://reactome.org/PathwayBrowser/#/R-DDI-71181 FAH cleaves 4FAA IEA Dictyostelium discoideum 18420 R-DDI-71401 https://reactome.org/PathwayBrowser/#/R-DDI-71401 OGDH dimer decarboxylates 2-OG IEA Dictyostelium discoideum 18420 R-DDI-71660 https://reactome.org/PathwayBrowser/#/R-DDI-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Dictyostelium discoideum 18420 R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 18420 R-DDI-71732 https://reactome.org/PathwayBrowser/#/R-DDI-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Dictyostelium discoideum 18420 R-DDI-71775 https://reactome.org/PathwayBrowser/#/R-DDI-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Dictyostelium discoideum 18420 R-DDI-71850 https://reactome.org/PathwayBrowser/#/R-DDI-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Dictyostelium discoideum 18420 R-DDI-74215 https://reactome.org/PathwayBrowser/#/R-DDI-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Dictyostelium discoideum 18420 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 18420 R-DDI-8939959 https://reactome.org/PathwayBrowser/#/R-DDI-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Dictyostelium discoideum 18420 R-DDI-8953499 https://reactome.org/PathwayBrowser/#/R-DDI-8953499 IMPAD1 hydrolyses PAP to AMP IEA Dictyostelium discoideum 18420 R-DDI-8955760 https://reactome.org/PathwayBrowser/#/R-DDI-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Dictyostelium discoideum 18420 R-DDI-8982667 https://reactome.org/PathwayBrowser/#/R-DDI-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Dictyostelium discoideum 18420 R-DDI-9012016 https://reactome.org/PathwayBrowser/#/R-DDI-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Dictyostelium discoideum 18420 R-DDI-9014741 https://reactome.org/PathwayBrowser/#/R-DDI-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Dictyostelium discoideum 18420 R-DDI-9014766 https://reactome.org/PathwayBrowser/#/R-DDI-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Dictyostelium discoideum 18420 R-DDI-9024993 https://reactome.org/PathwayBrowser/#/R-DDI-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Dictyostelium discoideum 18420 R-DDI-947531 https://reactome.org/PathwayBrowser/#/R-DDI-947531 Molybdenum ion transfer onto molybdopterin IEA Dictyostelium discoideum 18420 R-DDI-9638125 https://reactome.org/PathwayBrowser/#/R-DDI-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Dictyostelium discoideum 18420 R-DDI-9638127 https://reactome.org/PathwayBrowser/#/R-DDI-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Dictyostelium discoideum 18420 R-DDI-9717830 https://reactome.org/PathwayBrowser/#/R-DDI-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Dictyostelium discoideum 18420 R-DDI-9717834 https://reactome.org/PathwayBrowser/#/R-DDI-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Dictyostelium discoideum 18420 R-DDI-9717841 https://reactome.org/PathwayBrowser/#/R-DDI-9717841 holo-FDPS dimer binds NBPs IEA Dictyostelium discoideum 18420 R-DDI-9748951 https://reactome.org/PathwayBrowser/#/R-DDI-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Dictyostelium discoideum 18420 R-DDI-9754916 https://reactome.org/PathwayBrowser/#/R-DDI-9754916 NT5C2 tetramer phosphorylates RBV IEA Dictyostelium discoideum 18420 R-DDI-9754974 https://reactome.org/PathwayBrowser/#/R-DDI-9754974 ADK phosphorylates RBV IEA Dictyostelium discoideum 18420 R-DDI-9755078 https://reactome.org/PathwayBrowser/#/R-DDI-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Dictyostelium discoideum 18420 R-DDI-9770236 https://reactome.org/PathwayBrowser/#/R-DDI-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Dictyostelium discoideum 18420 R-DDI-977324 https://reactome.org/PathwayBrowser/#/R-DDI-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Dictyostelium discoideum 18420 R-DDI-983153 https://reactome.org/PathwayBrowser/#/R-DDI-983153 E1 mediated ubiquitin activation IEA Dictyostelium discoideum 18420 R-DDI-9853499 https://reactome.org/PathwayBrowser/#/R-DDI-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 18420 R-DDI-9853512 https://reactome.org/PathwayBrowser/#/R-DDI-9853512 DLST transfers succinyl to CoA IEA Dictyostelium discoideum 18420 R-DDI-9861616 https://reactome.org/PathwayBrowser/#/R-DDI-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 18420 R-DDI-9861667 https://reactome.org/PathwayBrowser/#/R-DDI-9861667 DLAT trimer transfers acetyl to CoA IEA Dictyostelium discoideum 18420 R-DDI-9861734 https://reactome.org/PathwayBrowser/#/R-DDI-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Dictyostelium discoideum 18420 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 18420 R-DME-109624 https://reactome.org/PathwayBrowser/#/R-DME-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Drosophila melanogaster 18420 R-DME-111524 https://reactome.org/PathwayBrowser/#/R-DME-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Drosophila melanogaster 18420 R-DME-111930 https://reactome.org/PathwayBrowser/#/R-DME-111930 Adenylate cyclase produces cAMP IEA Drosophila melanogaster 18420 R-DME-1237129 https://reactome.org/PathwayBrowser/#/R-DME-1237129 Acireductone is created IEA Drosophila melanogaster 18420 R-DME-1482961 https://reactome.org/PathwayBrowser/#/R-DME-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Drosophila melanogaster 18420 R-DME-1482962 https://reactome.org/PathwayBrowser/#/R-DME-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Drosophila melanogaster 18420 R-DME-1482973 https://reactome.org/PathwayBrowser/#/R-DME-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Drosophila melanogaster 18420 R-DME-1482976 https://reactome.org/PathwayBrowser/#/R-DME-1482976 CDP-DAG is converted to PI by CDIPT IEA Drosophila melanogaster 18420 R-DME-1483096 https://reactome.org/PathwayBrowser/#/R-DME-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Drosophila melanogaster 18420 R-DME-1483121 https://reactome.org/PathwayBrowser/#/R-DME-1483121 PA is converted to CDP-DAG by CDS1 IEA Drosophila melanogaster 18420 R-DME-1483159 https://reactome.org/PathwayBrowser/#/R-DME-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Drosophila melanogaster 18420 R-DME-1483203 https://reactome.org/PathwayBrowser/#/R-DME-1483203 PA is dephosphorylated to DAG by LPIN IEA Drosophila melanogaster 18420 R-DME-1606273 https://reactome.org/PathwayBrowser/#/R-DME-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Drosophila melanogaster 18420 R-DME-1606288 https://reactome.org/PathwayBrowser/#/R-DME-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Drosophila melanogaster 18420 R-DME-163741 https://reactome.org/PathwayBrowser/#/R-DME-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Drosophila melanogaster 18420 R-DME-163751 https://reactome.org/PathwayBrowser/#/R-DME-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Drosophila melanogaster 18420 R-DME-1675928 https://reactome.org/PathwayBrowser/#/R-DME-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Drosophila melanogaster 18420 R-DME-1675939 https://reactome.org/PathwayBrowser/#/R-DME-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Drosophila melanogaster 18420 R-DME-1675961 https://reactome.org/PathwayBrowser/#/R-DME-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Drosophila melanogaster 18420 R-DME-1676024 https://reactome.org/PathwayBrowser/#/R-DME-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Drosophila melanogaster 18420 R-DME-1676109 https://reactome.org/PathwayBrowser/#/R-DME-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Drosophila melanogaster 18420 R-DME-1676206 https://reactome.org/PathwayBrowser/#/R-DME-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Drosophila melanogaster 18420 R-DME-170666 https://reactome.org/PathwayBrowser/#/R-DME-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Drosophila melanogaster 18420 R-DME-170671 https://reactome.org/PathwayBrowser/#/R-DME-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Drosophila melanogaster 18420 R-DME-170672 https://reactome.org/PathwayBrowser/#/R-DME-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Drosophila melanogaster 18420 R-DME-170674 https://reactome.org/PathwayBrowser/#/R-DME-170674 Dissociation of the Gi alpha:G olf complex IEA Drosophila melanogaster 18420 R-DME-170676 https://reactome.org/PathwayBrowser/#/R-DME-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Drosophila melanogaster 18420 R-DME-170677 https://reactome.org/PathwayBrowser/#/R-DME-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Drosophila melanogaster 18420 R-DME-170685 https://reactome.org/PathwayBrowser/#/R-DME-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Drosophila melanogaster 18420 R-DME-170686 https://reactome.org/PathwayBrowser/#/R-DME-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Drosophila melanogaster 18420 R-DME-174394 https://reactome.org/PathwayBrowser/#/R-DME-174394 GSS:Mg2+ dimer synthesizes GSH IEA Drosophila melanogaster 18420 R-DME-1855154 https://reactome.org/PathwayBrowser/#/R-DME-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 18420 R-DME-1855165 https://reactome.org/PathwayBrowser/#/R-DME-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 18420 R-DME-1855166 https://reactome.org/PathwayBrowser/#/R-DME-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Drosophila melanogaster 18420 R-DME-1855198 https://reactome.org/PathwayBrowser/#/R-DME-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 18420 R-DME-1855205 https://reactome.org/PathwayBrowser/#/R-DME-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Drosophila melanogaster 18420 R-DME-1855208 https://reactome.org/PathwayBrowser/#/R-DME-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Drosophila melanogaster 18420 R-DME-1855210 https://reactome.org/PathwayBrowser/#/R-DME-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 18420 R-DME-1855211 https://reactome.org/PathwayBrowser/#/R-DME-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 18420 R-DME-1855232 https://reactome.org/PathwayBrowser/#/R-DME-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Drosophila melanogaster 18420 R-DME-187688 https://reactome.org/PathwayBrowser/#/R-DME-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Drosophila melanogaster 18420 R-DME-191303 https://reactome.org/PathwayBrowser/#/R-DME-191303 FDPS dimer transfers IPPP to GPP IEA Drosophila melanogaster 18420 R-DME-191322 https://reactome.org/PathwayBrowser/#/R-DME-191322 FDPS dimer transfers IPPP to DMAPP IEA Drosophila melanogaster 18420 R-DME-191382 https://reactome.org/PathwayBrowser/#/R-DME-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Drosophila melanogaster 18420 R-DME-196761 https://reactome.org/PathwayBrowser/#/R-DME-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Drosophila melanogaster 18420 R-DME-196964 https://reactome.org/PathwayBrowser/#/R-DME-196964 RFK:Mg2+ phosphorylates RIB IEA Drosophila melanogaster 18420 R-DME-197186 https://reactome.org/PathwayBrowser/#/R-DME-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Drosophila melanogaster 18420 R-DME-197235 https://reactome.org/PathwayBrowser/#/R-DME-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 18420 R-DME-200474 https://reactome.org/PathwayBrowser/#/R-DME-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 18420 R-DME-2023971 https://reactome.org/PathwayBrowser/#/R-DME-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 18420 R-DME-2023973 https://reactome.org/PathwayBrowser/#/R-DME-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 18420 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 18420 R-DME-204169 https://reactome.org/PathwayBrowser/#/R-DME-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Drosophila melanogaster 18420 R-DME-2162066 https://reactome.org/PathwayBrowser/#/R-DME-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Drosophila melanogaster 18420 R-DME-2162253 https://reactome.org/PathwayBrowser/#/R-DME-2162253 PDSS1,2 ligates FPP to IPPP IEA Drosophila melanogaster 18420 R-DME-2393954 https://reactome.org/PathwayBrowser/#/R-DME-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Drosophila melanogaster 18420 R-DME-2509827 https://reactome.org/PathwayBrowser/#/R-DME-2509827 ITPA hydrolyses ITP to IMP IEA Drosophila melanogaster 18420 R-DME-2509831 https://reactome.org/PathwayBrowser/#/R-DME-2509831 ITPA hydrolyses XTP to XMP IEA Drosophila melanogaster 18420 R-DME-2509838 https://reactome.org/PathwayBrowser/#/R-DME-2509838 ITPA hydrolyses dITP to dIMP IEA Drosophila melanogaster 18420 R-DME-265682 https://reactome.org/PathwayBrowser/#/R-DME-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Drosophila melanogaster 18420 R-DME-3322001 https://reactome.org/PathwayBrowser/#/R-DME-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Drosophila melanogaster 18420 R-DME-3322003 https://reactome.org/PathwayBrowser/#/R-DME-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Drosophila melanogaster 18420 R-DME-3322005 https://reactome.org/PathwayBrowser/#/R-DME-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Drosophila melanogaster 18420 R-DME-3322009 https://reactome.org/PathwayBrowser/#/R-DME-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Drosophila melanogaster 18420 R-DME-3322014 https://reactome.org/PathwayBrowser/#/R-DME-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Drosophila melanogaster 18420 R-DME-3322016 https://reactome.org/PathwayBrowser/#/R-DME-3322016 GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a IEA Drosophila melanogaster 18420 R-DME-3322019 https://reactome.org/PathwayBrowser/#/R-DME-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Drosophila melanogaster 18420 R-DME-3322025 https://reactome.org/PathwayBrowser/#/R-DME-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Drosophila melanogaster 18420 R-DME-3322041 https://reactome.org/PathwayBrowser/#/R-DME-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Drosophila melanogaster 18420 R-DME-3322057 https://reactome.org/PathwayBrowser/#/R-DME-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Drosophila melanogaster 18420 R-DME-354149 https://reactome.org/PathwayBrowser/#/R-DME-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Drosophila melanogaster 18420 R-DME-377640 https://reactome.org/PathwayBrowser/#/R-DME-377640 Autophosphorylation of SRC IEA Drosophila melanogaster 18420 R-DME-377641 https://reactome.org/PathwayBrowser/#/R-DME-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Drosophila melanogaster 18420 R-DME-377643 https://reactome.org/PathwayBrowser/#/R-DME-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Drosophila melanogaster 18420 R-DME-377644 https://reactome.org/PathwayBrowser/#/R-DME-377644 Release of CSK from SRC IEA Drosophila melanogaster 18420 R-DME-3780994 https://reactome.org/PathwayBrowser/#/R-DME-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Drosophila melanogaster 18420 R-DME-3780997 https://reactome.org/PathwayBrowser/#/R-DME-3780997 PPP1R3C binds to glycogen:GYG2:GYS2 IEA Drosophila melanogaster 18420 R-DME-3781011 https://reactome.org/PathwayBrowser/#/R-DME-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Drosophila melanogaster 18420 R-DME-3781018 https://reactome.org/PathwayBrowser/#/R-DME-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Drosophila melanogaster 18420 R-DME-3781023 https://reactome.org/PathwayBrowser/#/R-DME-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Drosophila melanogaster 18420 R-DME-3781024 https://reactome.org/PathwayBrowser/#/R-DME-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Drosophila melanogaster 18420 R-DME-3858495 https://reactome.org/PathwayBrowser/#/R-DME-3858495 DAAM1 recruits GTP-bound RHOA IEA Drosophila melanogaster 18420 R-DME-389611 https://reactome.org/PathwayBrowser/#/R-DME-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Drosophila melanogaster 18420 R-DME-4084989 https://reactome.org/PathwayBrowser/#/R-DME-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Drosophila melanogaster 18420 R-DME-429415 https://reactome.org/PathwayBrowser/#/R-DME-429415 SYK binds to integrin alphaIIb beta3 IEA Drosophila melanogaster 18420 R-DME-429441 https://reactome.org/PathwayBrowser/#/R-DME-429441 SYK activation by SRC IEA Drosophila melanogaster 18420 R-DME-442661 https://reactome.org/PathwayBrowser/#/R-DME-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol IEA Drosophila melanogaster 18420 R-DME-449937 https://reactome.org/PathwayBrowser/#/R-DME-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Drosophila melanogaster 18420 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 18420 R-DME-5218804 https://reactome.org/PathwayBrowser/#/R-DME-5218804 p38 MAPK activation by VEGFR IEA Drosophila melanogaster 18420 R-DME-5228992 https://reactome.org/PathwayBrowser/#/R-DME-5228992 ROCK1,ROCK2 are activated IEA Drosophila melanogaster 18420 R-DME-5336453 https://reactome.org/PathwayBrowser/#/R-DME-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Drosophila melanogaster 18420 R-DME-5339528 https://reactome.org/PathwayBrowser/#/R-DME-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Drosophila melanogaster 18420 R-DME-5339538 https://reactome.org/PathwayBrowser/#/R-DME-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Drosophila melanogaster 18420 R-DME-5610727 https://reactome.org/PathwayBrowser/#/R-DME-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Drosophila melanogaster 18420 R-DME-5655892 https://reactome.org/PathwayBrowser/#/R-DME-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Drosophila melanogaster 18420 R-DME-5655965 https://reactome.org/PathwayBrowser/#/R-DME-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Drosophila melanogaster 18420 R-DME-5656105 https://reactome.org/PathwayBrowser/#/R-DME-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Drosophila melanogaster 18420 R-DME-5656148 https://reactome.org/PathwayBrowser/#/R-DME-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Drosophila melanogaster 18420 R-DME-5656158 https://reactome.org/PathwayBrowser/#/R-DME-5656158 POLZ elongates POLI-incorporated dNMP IEA Drosophila melanogaster 18420 R-DME-5672972 https://reactome.org/PathwayBrowser/#/R-DME-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Drosophila melanogaster 18420 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 18420 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 18420 R-DME-5672980 https://reactome.org/PathwayBrowser/#/R-DME-5672980 Dissociation of RAS:RAF complex IEA Drosophila melanogaster 18420 R-DME-5694018 https://reactome.org/PathwayBrowser/#/R-DME-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Drosophila melanogaster 18420 R-DME-5696074 https://reactome.org/PathwayBrowser/#/R-DME-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Drosophila melanogaster 18420 R-DME-6787329 https://reactome.org/PathwayBrowser/#/R-DME-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Drosophila melanogaster 18420 R-DME-6788295 https://reactome.org/PathwayBrowser/#/R-DME-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Drosophila melanogaster 18420 R-DME-6788597 https://reactome.org/PathwayBrowser/#/R-DME-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Drosophila melanogaster 18420 R-DME-70479 https://reactome.org/PathwayBrowser/#/R-DME-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Drosophila melanogaster 18420 R-DME-70486 https://reactome.org/PathwayBrowser/#/R-DME-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Drosophila melanogaster 18420 R-DME-70494 https://reactome.org/PathwayBrowser/#/R-DME-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Drosophila melanogaster 18420 R-DME-70997 https://reactome.org/PathwayBrowser/#/R-DME-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Drosophila melanogaster 18420 R-DME-71037 https://reactome.org/PathwayBrowser/#/R-DME-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 18420 R-DME-71181 https://reactome.org/PathwayBrowser/#/R-DME-71181 FAH cleaves 4FAA IEA Drosophila melanogaster 18420 R-DME-71324 https://reactome.org/PathwayBrowser/#/R-DME-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 18420 R-DME-71335 https://reactome.org/PathwayBrowser/#/R-DME-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Drosophila melanogaster 18420 R-DME-71401 https://reactome.org/PathwayBrowser/#/R-DME-71401 OGDH dimer decarboxylates 2-OG IEA Drosophila melanogaster 18420 R-DME-71660 https://reactome.org/PathwayBrowser/#/R-DME-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Drosophila melanogaster 18420 R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 18420 R-DME-71732 https://reactome.org/PathwayBrowser/#/R-DME-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Drosophila melanogaster 18420 R-DME-71775 https://reactome.org/PathwayBrowser/#/R-DME-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Drosophila melanogaster 18420 R-DME-71850 https://reactome.org/PathwayBrowser/#/R-DME-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Drosophila melanogaster 18420 R-DME-73605 https://reactome.org/PathwayBrowser/#/R-DME-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Drosophila melanogaster 18420 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 18420 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 18420 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 18420 R-DME-8939959 https://reactome.org/PathwayBrowser/#/R-DME-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Drosophila melanogaster 18420 R-DME-8953499 https://reactome.org/PathwayBrowser/#/R-DME-8953499 IMPAD1 hydrolyses PAP to AMP IEA Drosophila melanogaster 18420 R-DME-8955760 https://reactome.org/PathwayBrowser/#/R-DME-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Drosophila melanogaster 18420 R-DME-8982667 https://reactome.org/PathwayBrowser/#/R-DME-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Drosophila melanogaster 18420 R-DME-9012016 https://reactome.org/PathwayBrowser/#/R-DME-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Drosophila melanogaster 18420 R-DME-9012036 https://reactome.org/PathwayBrowser/#/R-DME-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 18420 R-DME-9012268 https://reactome.org/PathwayBrowser/#/R-DME-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 18420 R-DME-9012349 https://reactome.org/PathwayBrowser/#/R-DME-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 18420 R-DME-936883 https://reactome.org/PathwayBrowser/#/R-DME-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Drosophila melanogaster 18420 R-DME-947531 https://reactome.org/PathwayBrowser/#/R-DME-947531 Molybdenum ion transfer onto molybdopterin IEA Drosophila melanogaster 18420 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 18420 R-DME-9621179 https://reactome.org/PathwayBrowser/#/R-DME-9621179 Cinaciguat binds sGC:NO IEA Drosophila melanogaster 18420 R-DME-9638125 https://reactome.org/PathwayBrowser/#/R-DME-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Drosophila melanogaster 18420 R-DME-9638127 https://reactome.org/PathwayBrowser/#/R-DME-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Drosophila melanogaster 18420 R-DME-9650858 https://reactome.org/PathwayBrowser/#/R-DME-9650858 Meglitinides bind ABCC8 IEA Drosophila melanogaster 18420 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 18420 R-DME-9657599 https://reactome.org/PathwayBrowser/#/R-DME-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Drosophila melanogaster 18420 R-DME-9657603 https://reactome.org/PathwayBrowser/#/R-DME-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Drosophila melanogaster 18420 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 18420 R-DME-9657608 https://reactome.org/PathwayBrowser/#/R-DME-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Drosophila melanogaster 18420 R-DME-9717830 https://reactome.org/PathwayBrowser/#/R-DME-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Drosophila melanogaster 18420 R-DME-9717834 https://reactome.org/PathwayBrowser/#/R-DME-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Drosophila melanogaster 18420 R-DME-9717841 https://reactome.org/PathwayBrowser/#/R-DME-9717841 holo-FDPS dimer binds NBPs IEA Drosophila melanogaster 18420 R-DME-9754916 https://reactome.org/PathwayBrowser/#/R-DME-9754916 NT5C2 tetramer phosphorylates RBV IEA Drosophila melanogaster 18420 R-DME-9754974 https://reactome.org/PathwayBrowser/#/R-DME-9754974 ADK phosphorylates RBV IEA Drosophila melanogaster 18420 R-DME-9755078 https://reactome.org/PathwayBrowser/#/R-DME-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Drosophila melanogaster 18420 R-DME-9770141 https://reactome.org/PathwayBrowser/#/R-DME-9770141 Formation of the Spliceosomal C* complex IEA Drosophila melanogaster 18420 R-DME-9770236 https://reactome.org/PathwayBrowser/#/R-DME-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Drosophila melanogaster 18420 R-DME-977324 https://reactome.org/PathwayBrowser/#/R-DME-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Drosophila melanogaster 18420 R-DME-983153 https://reactome.org/PathwayBrowser/#/R-DME-983153 E1 mediated ubiquitin activation IEA Drosophila melanogaster 18420 R-DME-9853499 https://reactome.org/PathwayBrowser/#/R-DME-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 18420 R-DME-9853512 https://reactome.org/PathwayBrowser/#/R-DME-9853512 DLST transfers succinyl to CoA IEA Drosophila melanogaster 18420 R-DME-9861616 https://reactome.org/PathwayBrowser/#/R-DME-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 18420 R-DME-9861631 https://reactome.org/PathwayBrowser/#/R-DME-9861631 ME1 tetramerizes IEA Drosophila melanogaster 18420 R-DME-9861660 https://reactome.org/PathwayBrowser/#/R-DME-9861660 ME1 tetramer decarboxylates OA to PYR IEA Drosophila melanogaster 18420 R-DME-9861667 https://reactome.org/PathwayBrowser/#/R-DME-9861667 DLAT trimer transfers acetyl to CoA IEA Drosophila melanogaster 18420 R-DME-9861734 https://reactome.org/PathwayBrowser/#/R-DME-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Drosophila melanogaster 18420 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 18420 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 18420 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 18420 R-DRE-109624 https://reactome.org/PathwayBrowser/#/R-DRE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Danio rerio 18420 R-DRE-109671 https://reactome.org/PathwayBrowser/#/R-DRE-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Danio rerio 18420 R-DRE-111215 https://reactome.org/PathwayBrowser/#/R-DRE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Danio rerio 18420 R-DRE-111524 https://reactome.org/PathwayBrowser/#/R-DRE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Danio rerio 18420 R-DRE-111930 https://reactome.org/PathwayBrowser/#/R-DRE-111930 Adenylate cyclase produces cAMP IEA Danio rerio 18420 R-DRE-1237129 https://reactome.org/PathwayBrowser/#/R-DRE-1237129 Acireductone is created IEA Danio rerio 18420 R-DRE-1482961 https://reactome.org/PathwayBrowser/#/R-DRE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Danio rerio 18420 R-DRE-1482962 https://reactome.org/PathwayBrowser/#/R-DRE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Danio rerio 18420 R-DRE-1482973 https://reactome.org/PathwayBrowser/#/R-DRE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Danio rerio 18420 R-DRE-1482976 https://reactome.org/PathwayBrowser/#/R-DRE-1482976 CDP-DAG is converted to PI by CDIPT IEA Danio rerio 18420 R-DRE-1483096 https://reactome.org/PathwayBrowser/#/R-DRE-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Danio rerio 18420 R-DRE-1483159 https://reactome.org/PathwayBrowser/#/R-DRE-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Danio rerio 18420 R-DRE-1483203 https://reactome.org/PathwayBrowser/#/R-DRE-1483203 PA is dephosphorylated to DAG by LPIN IEA Danio rerio 18420 R-DRE-1606273 https://reactome.org/PathwayBrowser/#/R-DRE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Danio rerio 18420 R-DRE-1606288 https://reactome.org/PathwayBrowser/#/R-DRE-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Danio rerio 18420 R-DRE-1676109 https://reactome.org/PathwayBrowser/#/R-DRE-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Danio rerio 18420 R-DRE-170666 https://reactome.org/PathwayBrowser/#/R-DRE-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Danio rerio 18420 R-DRE-170671 https://reactome.org/PathwayBrowser/#/R-DRE-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Danio rerio 18420 R-DRE-170672 https://reactome.org/PathwayBrowser/#/R-DRE-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Danio rerio 18420 R-DRE-170674 https://reactome.org/PathwayBrowser/#/R-DRE-170674 Dissociation of the Gi alpha:G olf complex IEA Danio rerio 18420 R-DRE-170676 https://reactome.org/PathwayBrowser/#/R-DRE-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Danio rerio 18420 R-DRE-170677 https://reactome.org/PathwayBrowser/#/R-DRE-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Danio rerio 18420 R-DRE-170685 https://reactome.org/PathwayBrowser/#/R-DRE-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Danio rerio 18420 R-DRE-170686 https://reactome.org/PathwayBrowser/#/R-DRE-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Danio rerio 18420 R-DRE-174391 https://reactome.org/PathwayBrowser/#/R-DRE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Danio rerio 18420 R-DRE-174394 https://reactome.org/PathwayBrowser/#/R-DRE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Danio rerio 18420 R-DRE-1855154 https://reactome.org/PathwayBrowser/#/R-DRE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 18420 R-DRE-1855159 https://reactome.org/PathwayBrowser/#/R-DRE-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Danio rerio 18420 R-DRE-1855162 https://reactome.org/PathwayBrowser/#/R-DRE-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Danio rerio 18420 R-DRE-1855165 https://reactome.org/PathwayBrowser/#/R-DRE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 18420 R-DRE-1855166 https://reactome.org/PathwayBrowser/#/R-DRE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Danio rerio 18420 R-DRE-1855169 https://reactome.org/PathwayBrowser/#/R-DRE-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Danio rerio 18420 R-DRE-1855171 https://reactome.org/PathwayBrowser/#/R-DRE-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Danio rerio 18420 R-DRE-1855172 https://reactome.org/PathwayBrowser/#/R-DRE-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Danio rerio 18420 R-DRE-1855197 https://reactome.org/PathwayBrowser/#/R-DRE-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Danio rerio 18420 R-DRE-1855198 https://reactome.org/PathwayBrowser/#/R-DRE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 18420 R-DRE-1855205 https://reactome.org/PathwayBrowser/#/R-DRE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Danio rerio 18420 R-DRE-1855210 https://reactome.org/PathwayBrowser/#/R-DRE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 18420 R-DRE-1855211 https://reactome.org/PathwayBrowser/#/R-DRE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 18420 R-DRE-1855218 https://reactome.org/PathwayBrowser/#/R-DRE-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Danio rerio 18420 R-DRE-1855219 https://reactome.org/PathwayBrowser/#/R-DRE-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Danio rerio 18420 R-DRE-187688 https://reactome.org/PathwayBrowser/#/R-DRE-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Danio rerio 18420 R-DRE-191303 https://reactome.org/PathwayBrowser/#/R-DRE-191303 FDPS dimer transfers IPPP to GPP IEA Danio rerio 18420 R-DRE-191322 https://reactome.org/PathwayBrowser/#/R-DRE-191322 FDPS dimer transfers IPPP to DMAPP IEA Danio rerio 18420 R-DRE-196761 https://reactome.org/PathwayBrowser/#/R-DRE-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Danio rerio 18420 R-DRE-197186 https://reactome.org/PathwayBrowser/#/R-DRE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Danio rerio 18420 R-DRE-197235 https://reactome.org/PathwayBrowser/#/R-DRE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 18420 R-DRE-2023971 https://reactome.org/PathwayBrowser/#/R-DRE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 18420 R-DRE-2023973 https://reactome.org/PathwayBrowser/#/R-DRE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 18420 R-DRE-2046085 https://reactome.org/PathwayBrowser/#/R-DRE-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Danio rerio 18420 R-DRE-2046098 https://reactome.org/PathwayBrowser/#/R-DRE-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Danio rerio 18420 R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Danio rerio 18420 R-DRE-2162253 https://reactome.org/PathwayBrowser/#/R-DRE-2162253 PDSS1,2 ligates FPP to IPPP IEA Danio rerio 18420 R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 18420 R-DRE-2393939 https://reactome.org/PathwayBrowser/#/R-DRE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 18420 R-DRE-2395818 https://reactome.org/PathwayBrowser/#/R-DRE-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Danio rerio 18420 R-DRE-2395849 https://reactome.org/PathwayBrowser/#/R-DRE-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Danio rerio 18420 R-DRE-2395872 https://reactome.org/PathwayBrowser/#/R-DRE-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Danio rerio 18420 R-DRE-2408551 https://reactome.org/PathwayBrowser/#/R-DRE-2408551 SeMet is converted to AdoSeMet by MAT IEA Danio rerio 18420 R-DRE-2509793 https://reactome.org/PathwayBrowser/#/R-DRE-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Danio rerio 18420 R-DRE-2509816 https://reactome.org/PathwayBrowser/#/R-DRE-2509816 NUDT16 hydrolyses IDP to IMP IEA Danio rerio 18420 R-DRE-2509827 https://reactome.org/PathwayBrowser/#/R-DRE-2509827 ITPA hydrolyses ITP to IMP IEA Danio rerio 18420 R-DRE-2509831 https://reactome.org/PathwayBrowser/#/R-DRE-2509831 ITPA hydrolyses XTP to XMP IEA Danio rerio 18420 R-DRE-2509838 https://reactome.org/PathwayBrowser/#/R-DRE-2509838 ITPA hydrolyses dITP to dIMP IEA Danio rerio 18420 R-DRE-3322001 https://reactome.org/PathwayBrowser/#/R-DRE-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Danio rerio 18420 R-DRE-3322003 https://reactome.org/PathwayBrowser/#/R-DRE-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Danio rerio 18420 R-DRE-3322025 https://reactome.org/PathwayBrowser/#/R-DRE-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Danio rerio 18420 R-DRE-3322041 https://reactome.org/PathwayBrowser/#/R-DRE-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Danio rerio 18420 R-DRE-354149 https://reactome.org/PathwayBrowser/#/R-DRE-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Danio rerio 18420 R-DRE-377640 https://reactome.org/PathwayBrowser/#/R-DRE-377640 Autophosphorylation of SRC IEA Danio rerio 18420 R-DRE-377641 https://reactome.org/PathwayBrowser/#/R-DRE-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Danio rerio 18420 R-DRE-377644 https://reactome.org/PathwayBrowser/#/R-DRE-377644 Release of CSK from SRC IEA Danio rerio 18420 R-DRE-3781018 https://reactome.org/PathwayBrowser/#/R-DRE-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Danio rerio 18420 R-DRE-3781023 https://reactome.org/PathwayBrowser/#/R-DRE-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Danio rerio 18420 R-DRE-3781024 https://reactome.org/PathwayBrowser/#/R-DRE-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Danio rerio 18420 R-DRE-3858495 https://reactome.org/PathwayBrowser/#/R-DRE-3858495 DAAM1 recruits GTP-bound RHOA IEA Danio rerio 18420 R-DRE-389611 https://reactome.org/PathwayBrowser/#/R-DRE-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Danio rerio 18420 R-DRE-4084989 https://reactome.org/PathwayBrowser/#/R-DRE-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Danio rerio 18420 R-DRE-426223 https://reactome.org/PathwayBrowser/#/R-DRE-426223 Cation influx mediated by TRPC3/6/7 IEA Danio rerio 18420 R-DRE-442661 https://reactome.org/PathwayBrowser/#/R-DRE-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol IEA Danio rerio 18420 R-DRE-449937 https://reactome.org/PathwayBrowser/#/R-DRE-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Danio rerio 18420 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 18420 R-DRE-5218804 https://reactome.org/PathwayBrowser/#/R-DRE-5218804 p38 MAPK activation by VEGFR IEA Danio rerio 18420 R-DRE-5228992 https://reactome.org/PathwayBrowser/#/R-DRE-5228992 ROCK1,ROCK2 are activated IEA Danio rerio 18420 R-DRE-5336453 https://reactome.org/PathwayBrowser/#/R-DRE-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Danio rerio 18420 R-DRE-5339538 https://reactome.org/PathwayBrowser/#/R-DRE-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Danio rerio 18420 R-DRE-5603114 https://reactome.org/PathwayBrowser/#/R-DRE-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Danio rerio 18420 R-DRE-5610727 https://reactome.org/PathwayBrowser/#/R-DRE-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Danio rerio 18420 R-DRE-5656148 https://reactome.org/PathwayBrowser/#/R-DRE-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Danio rerio 18420 R-DRE-5694018 https://reactome.org/PathwayBrowser/#/R-DRE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Danio rerio 18420 R-DRE-5696021 https://reactome.org/PathwayBrowser/#/R-DRE-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Danio rerio 18420 R-DRE-5696074 https://reactome.org/PathwayBrowser/#/R-DRE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Danio rerio 18420 R-DRE-6787329 https://reactome.org/PathwayBrowser/#/R-DRE-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Danio rerio 18420 R-DRE-6788295 https://reactome.org/PathwayBrowser/#/R-DRE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Danio rerio 18420 R-DRE-6788597 https://reactome.org/PathwayBrowser/#/R-DRE-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Danio rerio 18420 R-DRE-6788912 https://reactome.org/PathwayBrowser/#/R-DRE-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Danio rerio 18420 R-DRE-70349 https://reactome.org/PathwayBrowser/#/R-DRE-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Danio rerio 18420 R-DRE-70479 https://reactome.org/PathwayBrowser/#/R-DRE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Danio rerio 18420 R-DRE-70486 https://reactome.org/PathwayBrowser/#/R-DRE-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Danio rerio 18420 R-DRE-70494 https://reactome.org/PathwayBrowser/#/R-DRE-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Danio rerio 18420 R-DRE-70997 https://reactome.org/PathwayBrowser/#/R-DRE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Danio rerio 18420 R-DRE-71037 https://reactome.org/PathwayBrowser/#/R-DRE-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Danio rerio 18420 R-DRE-71401 https://reactome.org/PathwayBrowser/#/R-DRE-71401 OGDH dimer decarboxylates 2-OG IEA Danio rerio 18420 R-DRE-71660 https://reactome.org/PathwayBrowser/#/R-DRE-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Danio rerio 18420 R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 18420 R-DRE-71732 https://reactome.org/PathwayBrowser/#/R-DRE-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Danio rerio 18420 R-DRE-71850 https://reactome.org/PathwayBrowser/#/R-DRE-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Danio rerio 18420 R-DRE-73598 https://reactome.org/PathwayBrowser/#/R-DRE-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Danio rerio 18420 R-DRE-73605 https://reactome.org/PathwayBrowser/#/R-DRE-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Danio rerio 18420 R-DRE-74215 https://reactome.org/PathwayBrowser/#/R-DRE-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Danio rerio 18420 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 18420 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 18420 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 18420 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 18420 R-DRE-8939959 https://reactome.org/PathwayBrowser/#/R-DRE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Danio rerio 18420 R-DRE-8953499 https://reactome.org/PathwayBrowser/#/R-DRE-8953499 IMPAD1 hydrolyses PAP to AMP IEA Danio rerio 18420 R-DRE-8955760 https://reactome.org/PathwayBrowser/#/R-DRE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Danio rerio 18420 R-DRE-8982667 https://reactome.org/PathwayBrowser/#/R-DRE-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Danio rerio 18420 R-DRE-9012016 https://reactome.org/PathwayBrowser/#/R-DRE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Danio rerio 18420 R-DRE-9012036 https://reactome.org/PathwayBrowser/#/R-DRE-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Danio rerio 18420 R-DRE-9012268 https://reactome.org/PathwayBrowser/#/R-DRE-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Danio rerio 18420 R-DRE-9012349 https://reactome.org/PathwayBrowser/#/R-DRE-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Danio rerio 18420 R-DRE-9024993 https://reactome.org/PathwayBrowser/#/R-DRE-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Danio rerio 18420 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 18420 R-DRE-9621179 https://reactome.org/PathwayBrowser/#/R-DRE-9621179 Cinaciguat binds sGC:NO IEA Danio rerio 18420 R-DRE-9638125 https://reactome.org/PathwayBrowser/#/R-DRE-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Danio rerio 18420 R-DRE-9638127 https://reactome.org/PathwayBrowser/#/R-DRE-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Danio rerio 18420 R-DRE-9717841 https://reactome.org/PathwayBrowser/#/R-DRE-9717841 holo-FDPS dimer binds NBPs IEA Danio rerio 18420 R-DRE-9731228 https://reactome.org/PathwayBrowser/#/R-DRE-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Danio rerio 18420 R-DRE-9731590 https://reactome.org/PathwayBrowser/#/R-DRE-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Danio rerio 18420 R-DRE-9731613 https://reactome.org/PathwayBrowser/#/R-DRE-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Danio rerio 18420 R-DRE-9731632 https://reactome.org/PathwayBrowser/#/R-DRE-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Danio rerio 18420 R-DRE-9748951 https://reactome.org/PathwayBrowser/#/R-DRE-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Danio rerio 18420 R-DRE-9754974 https://reactome.org/PathwayBrowser/#/R-DRE-9754974 ADK phosphorylates RBV IEA Danio rerio 18420 R-DRE-9770236 https://reactome.org/PathwayBrowser/#/R-DRE-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Danio rerio 18420 R-DRE-977324 https://reactome.org/PathwayBrowser/#/R-DRE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Danio rerio 18420 R-DRE-983153 https://reactome.org/PathwayBrowser/#/R-DRE-983153 E1 mediated ubiquitin activation IEA Danio rerio 18420 R-DRE-9853499 https://reactome.org/PathwayBrowser/#/R-DRE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Danio rerio 18420 R-DRE-9853512 https://reactome.org/PathwayBrowser/#/R-DRE-9853512 DLST transfers succinyl to CoA IEA Danio rerio 18420 R-DRE-9861631 https://reactome.org/PathwayBrowser/#/R-DRE-9861631 ME1 tetramerizes IEA Danio rerio 18420 R-DRE-9861660 https://reactome.org/PathwayBrowser/#/R-DRE-9861660 ME1 tetramer decarboxylates OA to PYR IEA Danio rerio 18420 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 18420 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 18420 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 18420 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 18420 R-GGA-109624 https://reactome.org/PathwayBrowser/#/R-GGA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Gallus gallus 18420 R-GGA-109671 https://reactome.org/PathwayBrowser/#/R-GGA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Gallus gallus 18420 R-GGA-111215 https://reactome.org/PathwayBrowser/#/R-GGA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Gallus gallus 18420 R-GGA-111524 https://reactome.org/PathwayBrowser/#/R-GGA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Gallus gallus 18420 R-GGA-111930 https://reactome.org/PathwayBrowser/#/R-GGA-111930 Adenylate cyclase produces cAMP IEA Gallus gallus 18420 R-GGA-1237129 https://reactome.org/PathwayBrowser/#/R-GGA-1237129 Acireductone is created IEA Gallus gallus 18420 R-GGA-1482961 https://reactome.org/PathwayBrowser/#/R-GGA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Gallus gallus 18420 R-GGA-1482962 https://reactome.org/PathwayBrowser/#/R-GGA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Gallus gallus 18420 R-GGA-1482973 https://reactome.org/PathwayBrowser/#/R-GGA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Gallus gallus 18420 R-GGA-1483096 https://reactome.org/PathwayBrowser/#/R-GGA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Gallus gallus 18420 R-GGA-1483121 https://reactome.org/PathwayBrowser/#/R-GGA-1483121 PA is converted to CDP-DAG by CDS1 IEA Gallus gallus 18420 R-GGA-1483159 https://reactome.org/PathwayBrowser/#/R-GGA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Gallus gallus 18420 R-GGA-1483203 https://reactome.org/PathwayBrowser/#/R-GGA-1483203 PA is dephosphorylated to DAG by LPIN IEA Gallus gallus 18420 R-GGA-1606273 https://reactome.org/PathwayBrowser/#/R-GGA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Gallus gallus 18420 R-GGA-1606288 https://reactome.org/PathwayBrowser/#/R-GGA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Gallus gallus 18420 R-GGA-163741 https://reactome.org/PathwayBrowser/#/R-GGA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Gallus gallus 18420 R-GGA-163751 https://reactome.org/PathwayBrowser/#/R-GGA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Gallus gallus 18420 R-GGA-1675928 https://reactome.org/PathwayBrowser/#/R-GGA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Gallus gallus 18420 R-GGA-1675939 https://reactome.org/PathwayBrowser/#/R-GGA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Gallus gallus 18420 R-GGA-1675961 https://reactome.org/PathwayBrowser/#/R-GGA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Gallus gallus 18420 R-GGA-1676024 https://reactome.org/PathwayBrowser/#/R-GGA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Gallus gallus 18420 R-GGA-1676109 https://reactome.org/PathwayBrowser/#/R-GGA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Gallus gallus 18420 R-GGA-1676206 https://reactome.org/PathwayBrowser/#/R-GGA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Gallus gallus 18420 R-GGA-170666 https://reactome.org/PathwayBrowser/#/R-GGA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus 18420 R-GGA-170671 https://reactome.org/PathwayBrowser/#/R-GGA-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Gallus gallus 18420 R-GGA-170672 https://reactome.org/PathwayBrowser/#/R-GGA-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Gallus gallus 18420 R-GGA-170674 https://reactome.org/PathwayBrowser/#/R-GGA-170674 Dissociation of the Gi alpha:G olf complex IEA Gallus gallus 18420 R-GGA-170676 https://reactome.org/PathwayBrowser/#/R-GGA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Gallus gallus 18420 R-GGA-170677 https://reactome.org/PathwayBrowser/#/R-GGA-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Gallus gallus 18420 R-GGA-170685 https://reactome.org/PathwayBrowser/#/R-GGA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus 18420 R-GGA-170686 https://reactome.org/PathwayBrowser/#/R-GGA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Gallus gallus 18420 R-GGA-174391 https://reactome.org/PathwayBrowser/#/R-GGA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Gallus gallus 18420 R-GGA-174394 https://reactome.org/PathwayBrowser/#/R-GGA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Gallus gallus 18420 R-GGA-1855154 https://reactome.org/PathwayBrowser/#/R-GGA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 18420 R-GGA-1855159 https://reactome.org/PathwayBrowser/#/R-GGA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Gallus gallus 18420 R-GGA-1855162 https://reactome.org/PathwayBrowser/#/R-GGA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Gallus gallus 18420 R-GGA-1855165 https://reactome.org/PathwayBrowser/#/R-GGA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 18420 R-GGA-1855166 https://reactome.org/PathwayBrowser/#/R-GGA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Gallus gallus 18420 R-GGA-1855169 https://reactome.org/PathwayBrowser/#/R-GGA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 18420 R-GGA-1855171 https://reactome.org/PathwayBrowser/#/R-GGA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Gallus gallus 18420 R-GGA-1855172 https://reactome.org/PathwayBrowser/#/R-GGA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Gallus gallus 18420 R-GGA-1855197 https://reactome.org/PathwayBrowser/#/R-GGA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 18420 R-GGA-1855198 https://reactome.org/PathwayBrowser/#/R-GGA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 18420 R-GGA-1855205 https://reactome.org/PathwayBrowser/#/R-GGA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Gallus gallus 18420 R-GGA-1855208 https://reactome.org/PathwayBrowser/#/R-GGA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Gallus gallus 18420 R-GGA-1855210 https://reactome.org/PathwayBrowser/#/R-GGA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 18420 R-GGA-1855211 https://reactome.org/PathwayBrowser/#/R-GGA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 18420 R-GGA-1855218 https://reactome.org/PathwayBrowser/#/R-GGA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Gallus gallus 18420 R-GGA-1855219 https://reactome.org/PathwayBrowser/#/R-GGA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 18420 R-GGA-1855232 https://reactome.org/PathwayBrowser/#/R-GGA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Gallus gallus 18420 R-GGA-187688 https://reactome.org/PathwayBrowser/#/R-GGA-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Gallus gallus 18420 R-GGA-191303 https://reactome.org/PathwayBrowser/#/R-GGA-191303 FDPS dimer transfers IPPP to GPP IEA Gallus gallus 18420 R-GGA-191322 https://reactome.org/PathwayBrowser/#/R-GGA-191322 FDPS dimer transfers IPPP to DMAPP IEA Gallus gallus 18420 R-GGA-191382 https://reactome.org/PathwayBrowser/#/R-GGA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Gallus gallus 18420 R-GGA-191402 https://reactome.org/PathwayBrowser/#/R-GGA-191402 Reduction of presqualene diphosphate to form squalene IEA Gallus gallus 18420 R-GGA-191405 https://reactome.org/PathwayBrowser/#/R-GGA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Gallus gallus 18420 R-GGA-196761 https://reactome.org/PathwayBrowser/#/R-GGA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Gallus gallus 18420 R-GGA-196964 https://reactome.org/PathwayBrowser/#/R-GGA-196964 RFK:Mg2+ phosphorylates RIB IEA Gallus gallus 18420 R-GGA-197186 https://reactome.org/PathwayBrowser/#/R-GGA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Gallus gallus 18420 R-GGA-197235 https://reactome.org/PathwayBrowser/#/R-GGA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 18420 R-GGA-200474 https://reactome.org/PathwayBrowser/#/R-GGA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 18420 R-GGA-2023971 https://reactome.org/PathwayBrowser/#/R-GGA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 18420 R-GGA-2023973 https://reactome.org/PathwayBrowser/#/R-GGA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 18420 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 18420 R-GGA-204169 https://reactome.org/PathwayBrowser/#/R-GGA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Gallus gallus 18420 R-GGA-2046085 https://reactome.org/PathwayBrowser/#/R-GGA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Gallus gallus 18420 R-GGA-2046098 https://reactome.org/PathwayBrowser/#/R-GGA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Gallus gallus 18420 R-GGA-2132061 https://reactome.org/PathwayBrowser/#/R-GGA-2132061 Complement factor B binds to surface-bound C3b fragment IEA Gallus gallus 18420 R-GGA-2132096 https://reactome.org/PathwayBrowser/#/R-GGA-2132096 Formation of C4b:factor B complex IEA Gallus gallus 18420 R-GGA-216045 https://reactome.org/PathwayBrowser/#/R-GGA-216045 Collagen type I binds integrin alpha11beta1 IEA Gallus gallus 18420 R-GGA-216069 https://reactome.org/PathwayBrowser/#/R-GGA-216069 Interaction of integrin alphaDbeta2 with fibrin IEA Gallus gallus 18420 R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Gallus gallus 18420 R-GGA-2162066 https://reactome.org/PathwayBrowser/#/R-GGA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Gallus gallus 18420 R-GGA-2162253 https://reactome.org/PathwayBrowser/#/R-GGA-2162253 PDSS1,2 ligates FPP to IPPP IEA Gallus gallus 18420 R-GGA-2393939 https://reactome.org/PathwayBrowser/#/R-GGA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 18420 R-GGA-2393954 https://reactome.org/PathwayBrowser/#/R-GGA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 18420 R-GGA-2395818 https://reactome.org/PathwayBrowser/#/R-GGA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Gallus gallus 18420 R-GGA-2395849 https://reactome.org/PathwayBrowser/#/R-GGA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 18420 R-GGA-2395872 https://reactome.org/PathwayBrowser/#/R-GGA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Gallus gallus 18420 R-GGA-2408551 https://reactome.org/PathwayBrowser/#/R-GGA-2408551 SeMet is converted to AdoSeMet by MAT IEA Gallus gallus 18420 R-GGA-2509827 https://reactome.org/PathwayBrowser/#/R-GGA-2509827 ITPA hydrolyses ITP to IMP IEA Gallus gallus 18420 R-GGA-2509831 https://reactome.org/PathwayBrowser/#/R-GGA-2509831 ITPA hydrolyses XTP to XMP IEA Gallus gallus 18420 R-GGA-2509838 https://reactome.org/PathwayBrowser/#/R-GGA-2509838 ITPA hydrolyses dITP to dIMP IEA Gallus gallus 18420 R-GGA-265682 https://reactome.org/PathwayBrowser/#/R-GGA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Gallus gallus 18420 R-GGA-3322001 https://reactome.org/PathwayBrowser/#/R-GGA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Gallus gallus 18420 R-GGA-3322003 https://reactome.org/PathwayBrowser/#/R-GGA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Gallus gallus 18420 R-GGA-3322005 https://reactome.org/PathwayBrowser/#/R-GGA-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Gallus gallus 18420 R-GGA-3322009 https://reactome.org/PathwayBrowser/#/R-GGA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Gallus gallus 18420 R-GGA-3322014 https://reactome.org/PathwayBrowser/#/R-GGA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Gallus gallus 18420 R-GGA-3322016 https://reactome.org/PathwayBrowser/#/R-GGA-3322016 GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a IEA Gallus gallus 18420 R-GGA-3322019 https://reactome.org/PathwayBrowser/#/R-GGA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Gallus gallus 18420 R-GGA-3322025 https://reactome.org/PathwayBrowser/#/R-GGA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Gallus gallus 18420 R-GGA-3322041 https://reactome.org/PathwayBrowser/#/R-GGA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Gallus gallus 18420 R-GGA-3322057 https://reactome.org/PathwayBrowser/#/R-GGA-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Gallus gallus 18420 R-GGA-352981 https://reactome.org/PathwayBrowser/#/R-GGA-352981 phosphoenolpyruvate + H2O <=> 2-phosphoglycerate TAS Gallus gallus 18420 R-GGA-353044 https://reactome.org/PathwayBrowser/#/R-GGA-353044 2-phosphoglycerate <=> phosphoenolpyruvate + H2O TAS Gallus gallus 18420 R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 18420 R-GGA-354066 https://reactome.org/PathwayBrowser/#/R-GGA-354066 Translocation of PTK2 to Focal complexes IEA Gallus gallus 18420 R-GGA-354073 https://reactome.org/PathwayBrowser/#/R-GGA-354073 Autophosphorylation of PTK2 at Y397 IEA Gallus gallus 18420 R-GGA-354087 https://reactome.org/PathwayBrowser/#/R-GGA-354087 Recruitment of GRB2 to p-PTK2 IEA Gallus gallus 18420 R-GGA-354124 https://reactome.org/PathwayBrowser/#/R-GGA-354124 Phosphorylation of pPTK2 by SRC IEA Gallus gallus 18420 R-GGA-354149 https://reactome.org/PathwayBrowser/#/R-GGA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Gallus gallus 18420 R-GGA-354165 https://reactome.org/PathwayBrowser/#/R-GGA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Gallus gallus 18420 R-GGA-372693 https://reactome.org/PathwayBrowser/#/R-GGA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Gallus gallus 18420 R-GGA-372697 https://reactome.org/PathwayBrowser/#/R-GGA-372697 Crk binding to p130cas IEA Gallus gallus 18420 R-GGA-372705 https://reactome.org/PathwayBrowser/#/R-GGA-372705 Recruitment of BCAR1 to PTK2 complex IEA Gallus gallus 18420 R-GGA-377640 https://reactome.org/PathwayBrowser/#/R-GGA-377640 Autophosphorylation of SRC IEA Gallus gallus 18420 R-GGA-377641 https://reactome.org/PathwayBrowser/#/R-GGA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Gallus gallus 18420 R-GGA-377643 https://reactome.org/PathwayBrowser/#/R-GGA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Gallus gallus 18420 R-GGA-377644 https://reactome.org/PathwayBrowser/#/R-GGA-377644 Release of CSK from SRC IEA Gallus gallus 18420 R-GGA-3780994 https://reactome.org/PathwayBrowser/#/R-GGA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Gallus gallus 18420 R-GGA-3780997 https://reactome.org/PathwayBrowser/#/R-GGA-3780997 PPP1R3C binds to glycogen:GYG2:GYS2 IEA Gallus gallus 18420 R-GGA-3781011 https://reactome.org/PathwayBrowser/#/R-GGA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Gallus gallus 18420 R-GGA-3781018 https://reactome.org/PathwayBrowser/#/R-GGA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Gallus gallus 18420 R-GGA-3781023 https://reactome.org/PathwayBrowser/#/R-GGA-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Gallus gallus 18420 R-GGA-3781024 https://reactome.org/PathwayBrowser/#/R-GGA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Gallus gallus 18420 R-GGA-389611 https://reactome.org/PathwayBrowser/#/R-GGA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Gallus gallus 18420 R-GGA-392064 https://reactome.org/PathwayBrowser/#/R-GGA-392064 G alpha (z) inhibits adenylate cyclase IEA Gallus gallus 18420 R-GGA-4084989 https://reactome.org/PathwayBrowser/#/R-GGA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Gallus gallus 18420 R-GGA-426223 https://reactome.org/PathwayBrowser/#/R-GGA-426223 Cation influx mediated by TRPC3/6/7 IEA Gallus gallus 18420 R-GGA-429415 https://reactome.org/PathwayBrowser/#/R-GGA-429415 SYK binds to integrin alphaIIb beta3 IEA Gallus gallus 18420 R-GGA-429441 https://reactome.org/PathwayBrowser/#/R-GGA-429441 SYK activation by SRC IEA Gallus gallus 18420 R-GGA-442661 https://reactome.org/PathwayBrowser/#/R-GGA-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol IEA Gallus gallus 18420 R-GGA-449937 https://reactome.org/PathwayBrowser/#/R-GGA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Gallus gallus 18420 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 18420 R-GGA-5218804 https://reactome.org/PathwayBrowser/#/R-GGA-5218804 p38 MAPK activation by VEGFR IEA Gallus gallus 18420 R-GGA-5218826 https://reactome.org/PathwayBrowser/#/R-GGA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Gallus gallus 18420 R-GGA-5228992 https://reactome.org/PathwayBrowser/#/R-GGA-5228992 ROCK1,ROCK2 are activated IEA Gallus gallus 18420 R-GGA-5336453 https://reactome.org/PathwayBrowser/#/R-GGA-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Gallus gallus 18420 R-GGA-5336466 https://reactome.org/PathwayBrowser/#/R-GGA-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Gallus gallus 18420 R-GGA-5339528 https://reactome.org/PathwayBrowser/#/R-GGA-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Gallus gallus 18420 R-GGA-5339538 https://reactome.org/PathwayBrowser/#/R-GGA-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Gallus gallus 18420 R-GGA-5603114 https://reactome.org/PathwayBrowser/#/R-GGA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Gallus gallus 18420 R-GGA-5610727 https://reactome.org/PathwayBrowser/#/R-GGA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Gallus gallus 18420 R-GGA-5655835 https://reactome.org/PathwayBrowser/#/R-GGA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Gallus gallus 18420 R-GGA-5655892 https://reactome.org/PathwayBrowser/#/R-GGA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Gallus gallus 18420 R-GGA-5655965 https://reactome.org/PathwayBrowser/#/R-GGA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Gallus gallus 18420 R-GGA-5656148 https://reactome.org/PathwayBrowser/#/R-GGA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Gallus gallus 18420 R-GGA-5656158 https://reactome.org/PathwayBrowser/#/R-GGA-5656158 POLZ elongates POLI-incorporated dNMP IEA Gallus gallus 18420 R-GGA-5672972 https://reactome.org/PathwayBrowser/#/R-GGA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Gallus gallus 18420 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 18420 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 18420 R-GGA-5672980 https://reactome.org/PathwayBrowser/#/R-GGA-5672980 Dissociation of RAS:RAF complex IEA Gallus gallus 18420 R-GGA-5694018 https://reactome.org/PathwayBrowser/#/R-GGA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Gallus gallus 18420 R-GGA-5696021 https://reactome.org/PathwayBrowser/#/R-GGA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Gallus gallus 18420 R-GGA-5696074 https://reactome.org/PathwayBrowser/#/R-GGA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Gallus gallus 18420 R-GGA-6787329 https://reactome.org/PathwayBrowser/#/R-GGA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Gallus gallus 18420 R-GGA-6788295 https://reactome.org/PathwayBrowser/#/R-GGA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Gallus gallus 18420 R-GGA-6788597 https://reactome.org/PathwayBrowser/#/R-GGA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Gallus gallus 18420 R-GGA-6788912 https://reactome.org/PathwayBrowser/#/R-GGA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Gallus gallus 18420 R-GGA-70349 https://reactome.org/PathwayBrowser/#/R-GGA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Gallus gallus 18420 R-GGA-70479 https://reactome.org/PathwayBrowser/#/R-GGA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Gallus gallus 18420 R-GGA-70486 https://reactome.org/PathwayBrowser/#/R-GGA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Gallus gallus 18420 R-GGA-70494 https://reactome.org/PathwayBrowser/#/R-GGA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Gallus gallus 18420 R-GGA-70997 https://reactome.org/PathwayBrowser/#/R-GGA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Gallus gallus 18420 R-GGA-71037 https://reactome.org/PathwayBrowser/#/R-GGA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Gallus gallus 18420 R-GGA-71181 https://reactome.org/PathwayBrowser/#/R-GGA-71181 FAH cleaves 4FAA IEA Gallus gallus 18420 R-GGA-71324 https://reactome.org/PathwayBrowser/#/R-GGA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 18420 R-GGA-71335 https://reactome.org/PathwayBrowser/#/R-GGA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Gallus gallus 18420 R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus 18420 R-GGA-71660 https://reactome.org/PathwayBrowser/#/R-GGA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Gallus gallus 18420 R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 18420 R-GGA-71732 https://reactome.org/PathwayBrowser/#/R-GGA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Gallus gallus 18420 R-GGA-71775 https://reactome.org/PathwayBrowser/#/R-GGA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Gallus gallus 18420 R-GGA-71850 https://reactome.org/PathwayBrowser/#/R-GGA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Gallus gallus 18420 R-GGA-73598 https://reactome.org/PathwayBrowser/#/R-GGA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Gallus gallus 18420 R-GGA-74215 https://reactome.org/PathwayBrowser/#/R-GGA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Gallus gallus 18420 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 18420 R-GGA-74948 https://reactome.org/PathwayBrowser/#/R-GGA-74948 PP2A dephosphorylates p-RHO to RHO IEA Gallus gallus 18420 R-GGA-8850846 https://reactome.org/PathwayBrowser/#/R-GGA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Gallus gallus 18420 R-GGA-8850854 https://reactome.org/PathwayBrowser/#/R-GGA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Gallus gallus 18420 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 18420 R-GGA-8851110 https://reactome.org/PathwayBrowser/#/R-GGA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Gallus gallus 18420 R-GGA-8851129 https://reactome.org/PathwayBrowser/#/R-GGA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Gallus gallus 18420 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 18420 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 18420 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 18420 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 18420 R-GGA-8939959 https://reactome.org/PathwayBrowser/#/R-GGA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Gallus gallus 18420 R-GGA-8955760 https://reactome.org/PathwayBrowser/#/R-GGA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Gallus gallus 18420 R-GGA-8982667 https://reactome.org/PathwayBrowser/#/R-GGA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Gallus gallus 18420 R-GGA-9012016 https://reactome.org/PathwayBrowser/#/R-GGA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Gallus gallus 18420 R-GGA-9012036 https://reactome.org/PathwayBrowser/#/R-GGA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Gallus gallus 18420 R-GGA-9012349 https://reactome.org/PathwayBrowser/#/R-GGA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Gallus gallus 18420 R-GGA-9014741 https://reactome.org/PathwayBrowser/#/R-GGA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Gallus gallus 18420 R-GGA-9014766 https://reactome.org/PathwayBrowser/#/R-GGA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Gallus gallus 18420 R-GGA-9024993 https://reactome.org/PathwayBrowser/#/R-GGA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Gallus gallus 18420 R-GGA-936883 https://reactome.org/PathwayBrowser/#/R-GGA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Gallus gallus 18420 R-GGA-947531 https://reactome.org/PathwayBrowser/#/R-GGA-947531 Molybdenum ion transfer onto molybdopterin IEA Gallus gallus 18420 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 18420 R-GGA-9621179 https://reactome.org/PathwayBrowser/#/R-GGA-9621179 Cinaciguat binds sGC:NO IEA Gallus gallus 18420 R-GGA-9638125 https://reactome.org/PathwayBrowser/#/R-GGA-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Gallus gallus 18420 R-GGA-9638127 https://reactome.org/PathwayBrowser/#/R-GGA-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Gallus gallus 18420 R-GGA-9650858 https://reactome.org/PathwayBrowser/#/R-GGA-9650858 Meglitinides bind ABCC8 IEA Gallus gallus 18420 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 18420 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus 18420 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus 18420 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 18420 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus 18420 R-GGA-9717830 https://reactome.org/PathwayBrowser/#/R-GGA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Gallus gallus 18420 R-GGA-9717834 https://reactome.org/PathwayBrowser/#/R-GGA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Gallus gallus 18420 R-GGA-9717841 https://reactome.org/PathwayBrowser/#/R-GGA-9717841 holo-FDPS dimer binds NBPs IEA Gallus gallus 18420 R-GGA-9731228 https://reactome.org/PathwayBrowser/#/R-GGA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Gallus gallus 18420 R-GGA-9731590 https://reactome.org/PathwayBrowser/#/R-GGA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Gallus gallus 18420 R-GGA-9731613 https://reactome.org/PathwayBrowser/#/R-GGA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Gallus gallus 18420 R-GGA-9731632 https://reactome.org/PathwayBrowser/#/R-GGA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Gallus gallus 18420 R-GGA-9748951 https://reactome.org/PathwayBrowser/#/R-GGA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Gallus gallus 18420 R-GGA-9754916 https://reactome.org/PathwayBrowser/#/R-GGA-9754916 NT5C2 tetramer phosphorylates RBV IEA Gallus gallus 18420 R-GGA-9754974 https://reactome.org/PathwayBrowser/#/R-GGA-9754974 ADK phosphorylates RBV IEA Gallus gallus 18420 R-GGA-9755078 https://reactome.org/PathwayBrowser/#/R-GGA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Gallus gallus 18420 R-GGA-977324 https://reactome.org/PathwayBrowser/#/R-GGA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Gallus gallus 18420 R-GGA-983153 https://reactome.org/PathwayBrowser/#/R-GGA-983153 E1 mediated ubiquitin activation IEA Gallus gallus 18420 R-GGA-9853499 https://reactome.org/PathwayBrowser/#/R-GGA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 18420 R-GGA-9853512 https://reactome.org/PathwayBrowser/#/R-GGA-9853512 DLST transfers succinyl to CoA IEA Gallus gallus 18420 R-GGA-9861616 https://reactome.org/PathwayBrowser/#/R-GGA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 18420 R-GGA-9861631 https://reactome.org/PathwayBrowser/#/R-GGA-9861631 ME1 tetramerizes IEA Gallus gallus 18420 R-GGA-9861642 https://reactome.org/PathwayBrowser/#/R-GGA-9861642 NEK1 phosphorylates ME1 IEA Gallus gallus 18420 R-GGA-9861660 https://reactome.org/PathwayBrowser/#/R-GGA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Gallus gallus 18420 R-GGA-9861667 https://reactome.org/PathwayBrowser/#/R-GGA-9861667 DLAT trimer transfers acetyl to CoA IEA Gallus gallus 18420 R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus 18420 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 18420 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 18420 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 18420 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 18420 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 18420 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 18420 R-HSA-109624 https://reactome.org/PathwayBrowser/#/R-HSA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) TAS Homo sapiens 18420 R-HSA-109671 https://reactome.org/PathwayBrowser/#/R-HSA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) TAS Homo sapiens 18420 R-HSA-111215 https://reactome.org/PathwayBrowser/#/R-HSA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate TAS Homo sapiens 18420 R-HSA-111524 https://reactome.org/PathwayBrowser/#/R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] TAS Homo sapiens 18420 R-HSA-111930 https://reactome.org/PathwayBrowser/#/R-HSA-111930 Adenylate cyclase produces cAMP TAS Homo sapiens 18420 R-HSA-114563 https://reactome.org/PathwayBrowser/#/R-HSA-114563 Collagen type I binds integrin alpha1beta1, alpha2beta1, alpha10beta1 IEA Homo sapiens 18420 R-HSA-1237129 https://reactome.org/PathwayBrowser/#/R-HSA-1237129 Acireductone is created TAS Homo sapiens 18420 R-HSA-1482961 https://reactome.org/PathwayBrowser/#/R-HSA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane TAS Homo sapiens 18420 R-HSA-1482962 https://reactome.org/PathwayBrowser/#/R-HSA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 TAS Homo sapiens 18420 R-HSA-1482973 https://reactome.org/PathwayBrowser/#/R-HSA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane TAS Homo sapiens 18420 R-HSA-1482976 https://reactome.org/PathwayBrowser/#/R-HSA-1482976 CDP-DAG is converted to PI by CDIPT TAS Homo sapiens 18420 R-HSA-1483096 https://reactome.org/PathwayBrowser/#/R-HSA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 TAS Homo sapiens 18420 R-HSA-1483121 https://reactome.org/PathwayBrowser/#/R-HSA-1483121 PA is converted to CDP-DAG by CDS1 TAS Homo sapiens 18420 R-HSA-1483159 https://reactome.org/PathwayBrowser/#/R-HSA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 TAS Homo sapiens 18420 R-HSA-1483203 https://reactome.org/PathwayBrowser/#/R-HSA-1483203 PA is dephosphorylated to DAG by LPIN TAS Homo sapiens 18420 R-HSA-1606273 https://reactome.org/PathwayBrowser/#/R-HSA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) TAS Homo sapiens 18420 R-HSA-1606288 https://reactome.org/PathwayBrowser/#/R-HSA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) TAS Homo sapiens 18420 R-HSA-163617 https://reactome.org/PathwayBrowser/#/R-HSA-163617 G alpha (s) activates adenylate cyclase TAS Homo sapiens 18420 R-HSA-163741 https://reactome.org/PathwayBrowser/#/R-HSA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate TAS Homo sapiens 18420 R-HSA-163751 https://reactome.org/PathwayBrowser/#/R-HSA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate TAS Homo sapiens 18420 R-HSA-164377 https://reactome.org/PathwayBrowser/#/R-HSA-164377 Activated Adenylate cyclase catalyses cAMP synthesis TAS Homo sapiens 18420 R-HSA-1675928 https://reactome.org/PathwayBrowser/#/R-HSA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane TAS Homo sapiens 18420 R-HSA-1675939 https://reactome.org/PathwayBrowser/#/R-HSA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane TAS Homo sapiens 18420 R-HSA-1675961 https://reactome.org/PathwayBrowser/#/R-HSA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane TAS Homo sapiens 18420 R-HSA-1676024 https://reactome.org/PathwayBrowser/#/R-HSA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane TAS Homo sapiens 18420 R-HSA-1676109 https://reactome.org/PathwayBrowser/#/R-HSA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane TAS Homo sapiens 18420 R-HSA-1676206 https://reactome.org/PathwayBrowser/#/R-HSA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane TAS Homo sapiens 18420 R-HSA-170666 https://reactome.org/PathwayBrowser/#/R-HSA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf TAS Homo sapiens 18420 R-HSA-170671 https://reactome.org/PathwayBrowser/#/R-HSA-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex TAS Homo sapiens 18420 R-HSA-170672 https://reactome.org/PathwayBrowser/#/R-HSA-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it TAS Homo sapiens 18420 R-HSA-170674 https://reactome.org/PathwayBrowser/#/R-HSA-170674 Dissociation of the Gi alpha:G olf complex TAS Homo sapiens 18420 R-HSA-170676 https://reactome.org/PathwayBrowser/#/R-HSA-170676 Adenylate cyclase converts ATP into cyclic AMP TAS Homo sapiens 18420 R-HSA-170677 https://reactome.org/PathwayBrowser/#/R-HSA-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates TAS Homo sapiens 18420 R-HSA-170685 https://reactome.org/PathwayBrowser/#/R-HSA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf TAS Homo sapiens 18420 R-HSA-170686 https://reactome.org/PathwayBrowser/#/R-HSA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha TAS Homo sapiens 18420 R-HSA-171011 https://reactome.org/PathwayBrowser/#/R-HSA-171011 Binding and activation of MAP Kinase IEA Homo sapiens 18420 R-HSA-174391 https://reactome.org/PathwayBrowser/#/R-HSA-174391 MAT1A multimers transfer Ado from ATP to L-Met TAS Homo sapiens 18420 R-HSA-174394 https://reactome.org/PathwayBrowser/#/R-HSA-174394 GSS:Mg2+ dimer synthesizes GSH TAS Homo sapiens 18420 R-HSA-1855154 https://reactome.org/PathwayBrowser/#/R-HSA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 18420 R-HSA-1855159 https://reactome.org/PathwayBrowser/#/R-HSA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol TAS Homo sapiens 18420 R-HSA-1855162 https://reactome.org/PathwayBrowser/#/R-HSA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol TAS Homo sapiens 18420 R-HSA-1855165 https://reactome.org/PathwayBrowser/#/R-HSA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 18420 R-HSA-1855166 https://reactome.org/PathwayBrowser/#/R-HSA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol TAS Homo sapiens 18420 R-HSA-1855169 https://reactome.org/PathwayBrowser/#/R-HSA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 18420 R-HSA-1855171 https://reactome.org/PathwayBrowser/#/R-HSA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol TAS Homo sapiens 18420 R-HSA-1855172 https://reactome.org/PathwayBrowser/#/R-HSA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol TAS Homo sapiens 18420 R-HSA-1855197 https://reactome.org/PathwayBrowser/#/R-HSA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 18420 R-HSA-1855198 https://reactome.org/PathwayBrowser/#/R-HSA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 18420 R-HSA-1855205 https://reactome.org/PathwayBrowser/#/R-HSA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol TAS Homo sapiens 18420 R-HSA-1855208 https://reactome.org/PathwayBrowser/#/R-HSA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol TAS Homo sapiens 18420 R-HSA-1855210 https://reactome.org/PathwayBrowser/#/R-HSA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 18420 R-HSA-1855211 https://reactome.org/PathwayBrowser/#/R-HSA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 18420 R-HSA-1855218 https://reactome.org/PathwayBrowser/#/R-HSA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol TAS Homo sapiens 18420 R-HSA-1855219 https://reactome.org/PathwayBrowser/#/R-HSA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 18420 R-HSA-1855232 https://reactome.org/PathwayBrowser/#/R-HSA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol TAS Homo sapiens 18420 R-HSA-187688 https://reactome.org/PathwayBrowser/#/R-HSA-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 TAS Homo sapiens 18420 R-HSA-191303 https://reactome.org/PathwayBrowser/#/R-HSA-191303 FDPS dimer transfers IPPP to GPP TAS Homo sapiens 18420 R-HSA-191322 https://reactome.org/PathwayBrowser/#/R-HSA-191322 FDPS dimer transfers IPPP to DMAPP TAS Homo sapiens 18420 R-HSA-191382 https://reactome.org/PathwayBrowser/#/R-HSA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate TAS Homo sapiens 18420 R-HSA-191402 https://reactome.org/PathwayBrowser/#/R-HSA-191402 Reduction of presqualene diphosphate to form squalene TAS Homo sapiens 18420 R-HSA-191405 https://reactome.org/PathwayBrowser/#/R-HSA-191405 Two FPP molecules dimerize to form presqualene diphosphate TAS Homo sapiens 18420 R-HSA-193672 https://reactome.org/PathwayBrowser/#/R-HSA-193672 Sphingomyelinase is activated by the NGF:p75NTR complex IEA Homo sapiens 18420 R-HSA-193706 https://reactome.org/PathwayBrowser/#/R-HSA-193706 Production of ceramide which can activate JNK and other targets IEA Homo sapiens 18420 R-HSA-196761 https://reactome.org/PathwayBrowser/#/R-HSA-196761 2xTPK1:Mg2+ phosphorylates THMN TAS Homo sapiens 18420 R-HSA-196964 https://reactome.org/PathwayBrowser/#/R-HSA-196964 RFK:Mg2+ phosphorylates RIB TAS Homo sapiens 18420 R-HSA-197186 https://reactome.org/PathwayBrowser/#/R-HSA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN TAS Homo sapiens 18420 R-HSA-197235 https://reactome.org/PathwayBrowser/#/R-HSA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 18420 R-HSA-200474 https://reactome.org/PathwayBrowser/#/R-HSA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 18420 R-HSA-2023971 https://reactome.org/PathwayBrowser/#/R-HSA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 18420 R-HSA-2023973 https://reactome.org/PathwayBrowser/#/R-HSA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 18420 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 18420 R-HSA-204169 https://reactome.org/PathwayBrowser/#/R-HSA-204169 PDP1,2 dephosphorylate p-lipo-PDH TAS Homo sapiens 18420 R-HSA-2046085 https://reactome.org/PathwayBrowser/#/R-HSA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA TAS Homo sapiens 18420 R-HSA-2046098 https://reactome.org/PathwayBrowser/#/R-HSA-2046098 Activation of linoleic acid to linoleoyl-CoA TAS Homo sapiens 18420 R-HSA-216040 https://reactome.org/PathwayBrowser/#/R-HSA-216040 Collagen type IV networks bind integrins alpha1beta1, alpha2beta1 IEA Homo sapiens 18420 R-HSA-216043 https://reactome.org/PathwayBrowser/#/R-HSA-216043 Collagen type II binds integrin alpha10beta1 TAS Homo sapiens 18420 R-HSA-216045 https://reactome.org/PathwayBrowser/#/R-HSA-216045 Collagen type I binds integrin alpha11beta1 TAS Homo sapiens 18420 R-HSA-216069 https://reactome.org/PathwayBrowser/#/R-HSA-216069 Interaction of integrin alphaDbeta2 with fibrin TAS Homo sapiens 18420 R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 TAS Homo sapiens 18420 R-HSA-2162066 https://reactome.org/PathwayBrowser/#/R-HSA-2162066 carbovir + IMP => carbovir monophosphate + inosine TAS Homo sapiens 18420 R-HSA-2162253 https://reactome.org/PathwayBrowser/#/R-HSA-2162253 PDSS1,2 ligates FPP to IPPP TAS Homo sapiens 18420 R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 18420 R-HSA-2393939 https://reactome.org/PathwayBrowser/#/R-HSA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 18420 R-HSA-2393954 https://reactome.org/PathwayBrowser/#/R-HSA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 18420 R-HSA-2395818 https://reactome.org/PathwayBrowser/#/R-HSA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP TAS Homo sapiens 18420 R-HSA-2395849 https://reactome.org/PathwayBrowser/#/R-HSA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 18420 R-HSA-2395872 https://reactome.org/PathwayBrowser/#/R-HSA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP TAS Homo sapiens 18420 R-HSA-2408507 https://reactome.org/PathwayBrowser/#/R-HSA-2408507 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK IEA Homo sapiens 18420 R-HSA-2408551 https://reactome.org/PathwayBrowser/#/R-HSA-2408551 SeMet is converted to AdoSeMet by MAT TAS Homo sapiens 18420 R-HSA-2509793 https://reactome.org/PathwayBrowser/#/R-HSA-2509793 NUDT16 hydrolyses dIDP to dIMP TAS Homo sapiens 18420 R-HSA-2509816 https://reactome.org/PathwayBrowser/#/R-HSA-2509816 NUDT16 hydrolyses IDP to IMP TAS Homo sapiens 18420 R-HSA-2509827 https://reactome.org/PathwayBrowser/#/R-HSA-2509827 ITPA hydrolyses ITP to IMP TAS Homo sapiens 18420 R-HSA-2509831 https://reactome.org/PathwayBrowser/#/R-HSA-2509831 ITPA hydrolyses XTP to XMP TAS Homo sapiens 18420 R-HSA-2509838 https://reactome.org/PathwayBrowser/#/R-HSA-2509838 ITPA hydrolyses dITP to dIMP TAS Homo sapiens 18420 R-HSA-265682 https://reactome.org/PathwayBrowser/#/R-HSA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel TAS Homo sapiens 18420 R-HSA-3244605 https://reactome.org/PathwayBrowser/#/R-HSA-3244605 TREX1 binds retroviral-derived DNA TAS Homo sapiens 18420 R-HSA-3245943 https://reactome.org/PathwayBrowser/#/R-HSA-3245943 Viral DNA cleavage by TREX1 TAS Homo sapiens 18420 R-HSA-3322001 https://reactome.org/PathwayBrowser/#/R-HSA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 TAS Homo sapiens 18420 R-HSA-3322003 https://reactome.org/PathwayBrowser/#/R-HSA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b TAS Homo sapiens 18420 R-HSA-3322005 https://reactome.org/PathwayBrowser/#/R-HSA-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a TAS Homo sapiens 18420 R-HSA-3322009 https://reactome.org/PathwayBrowser/#/R-HSA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 TAS Homo sapiens 18420 R-HSA-3322014 https://reactome.org/PathwayBrowser/#/R-HSA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a TAS Homo sapiens 18420 R-HSA-3322016 https://reactome.org/PathwayBrowser/#/R-HSA-3322016 GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a TAS Homo sapiens 18420 R-HSA-3322019 https://reactome.org/PathwayBrowser/#/R-HSA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b TAS Homo sapiens 18420 R-HSA-3322025 https://reactome.org/PathwayBrowser/#/R-HSA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a TAS Homo sapiens 18420 R-HSA-3322041 https://reactome.org/PathwayBrowser/#/R-HSA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 TAS Homo sapiens 18420 R-HSA-3322057 https://reactome.org/PathwayBrowser/#/R-HSA-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b TAS Homo sapiens 18420 R-HSA-354066 https://reactome.org/PathwayBrowser/#/R-HSA-354066 Translocation of PTK2 to Focal complexes TAS Homo sapiens 18420 R-HSA-354073 https://reactome.org/PathwayBrowser/#/R-HSA-354073 Autophosphorylation of PTK2 at Y397 TAS Homo sapiens 18420 R-HSA-354087 https://reactome.org/PathwayBrowser/#/R-HSA-354087 Recruitment of GRB2 to p-PTK2 TAS Homo sapiens 18420 R-HSA-354124 https://reactome.org/PathwayBrowser/#/R-HSA-354124 Phosphorylation of pPTK2 by SRC TAS Homo sapiens 18420 R-HSA-354149 https://reactome.org/PathwayBrowser/#/R-HSA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen TAS Homo sapiens 18420 R-HSA-354165 https://reactome.org/PathwayBrowser/#/R-HSA-354165 Interaction of SOS with GRB2 bound to FADK1 TAS Homo sapiens 18420 R-HSA-372693 https://reactome.org/PathwayBrowser/#/R-HSA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex TAS Homo sapiens 18420 R-HSA-372697 https://reactome.org/PathwayBrowser/#/R-HSA-372697 Crk binding to p130cas TAS Homo sapiens 18420 R-HSA-372705 https://reactome.org/PathwayBrowser/#/R-HSA-372705 Recruitment of BCAR1 to PTK2 complex TAS Homo sapiens 18420 R-HSA-377640 https://reactome.org/PathwayBrowser/#/R-HSA-377640 Autophosphorylation of SRC TAS Homo sapiens 18420 R-HSA-377641 https://reactome.org/PathwayBrowser/#/R-HSA-377641 Clustering of Integrin alphaIIb beta3 complexes TAS Homo sapiens 18420 R-HSA-377643 https://reactome.org/PathwayBrowser/#/R-HSA-377643 Dephosphorylation of inactive SRC by PTPB1 TAS Homo sapiens 18420 R-HSA-377644 https://reactome.org/PathwayBrowser/#/R-HSA-377644 Release of CSK from SRC TAS Homo sapiens 18420 R-HSA-3780994 https://reactome.org/PathwayBrowser/#/R-HSA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 TAS Homo sapiens 18420 R-HSA-3780995 https://reactome.org/PathwayBrowser/#/R-HSA-3780995 NHLRC1 mediated ubiquitination of EPM2A (laforin) and PPP1RC3 (PTG) associated with glycogen-GYG2 TAS Homo sapiens 18420 R-HSA-3780997 https://reactome.org/PathwayBrowser/#/R-HSA-3780997 PPP1R3C binds to glycogen:GYG2:GYS2 TAS Homo sapiens 18420 R-HSA-3781001 https://reactome.org/PathwayBrowser/#/R-HSA-3781001 EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex TAS Homo sapiens 18420 R-HSA-3781009 https://reactome.org/PathwayBrowser/#/R-HSA-3781009 NHLRC1 mediated ubiquitination of EPM2A and PPP1RC3 associated with glycogen-GYG1 TAS Homo sapiens 18420 R-HSA-3781011 https://reactome.org/PathwayBrowser/#/R-HSA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 TAS Homo sapiens 18420 R-HSA-3781018 https://reactome.org/PathwayBrowser/#/R-HSA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 TAS Homo sapiens 18420 R-HSA-3781021 https://reactome.org/PathwayBrowser/#/R-HSA-3781021 EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG2 complex TAS Homo sapiens 18420 R-HSA-3781023 https://reactome.org/PathwayBrowser/#/R-HSA-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 TAS Homo sapiens 18420 R-HSA-3781024 https://reactome.org/PathwayBrowser/#/R-HSA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 TAS Homo sapiens 18420 R-HSA-3791349 https://reactome.org/PathwayBrowser/#/R-HSA-3791349 Defective EPM2A does not dephosphorylate phosphoglycogen (type 2A disease) TAS Homo sapiens 18420 R-HSA-3797226 https://reactome.org/PathwayBrowser/#/R-HSA-3797226 Defective NHLRC1 does not ubiquitinate EPM2A (laforin) and PPP1R3C (PTG) (type 2B disease) TAS Homo sapiens 18420 R-HSA-3814838 https://reactome.org/PathwayBrowser/#/R-HSA-3814838 Defective GYG1 is not autoglucosyolated TAS Homo sapiens 18420 R-HSA-3828061 https://reactome.org/PathwayBrowser/#/R-HSA-3828061 Defective GYS1 does not transfer glucose to growing glycogen chains TAS Homo sapiens 18420 R-HSA-3858495 https://reactome.org/PathwayBrowser/#/R-HSA-3858495 DAAM1 recruits GTP-bound RHOA TAS Homo sapiens 18420 R-HSA-3858506 https://reactome.org/PathwayBrowser/#/R-HSA-3858506 Defective GYS2 does not transfer glucose to growing glycogen chains TAS Homo sapiens 18420 R-HSA-3878762 https://reactome.org/PathwayBrowser/#/R-HSA-3878762 Defective GBE1 does not catalyze branch formation in growing glycogen chains (liver) TAS Homo sapiens 18420 R-HSA-389611 https://reactome.org/PathwayBrowser/#/R-HSA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA TAS Homo sapiens 18420 R-HSA-392064 https://reactome.org/PathwayBrowser/#/R-HSA-392064 G alpha (z) inhibits adenylate cyclase TAS Homo sapiens 18420 R-HSA-392129 https://reactome.org/PathwayBrowser/#/R-HSA-392129 Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate IEA Homo sapiens 18420 R-HSA-392143 https://reactome.org/PathwayBrowser/#/R-HSA-392143 NO binds to Guanylate Cyclase IEA Homo sapiens 18420 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 18420 R-HSA-392206 https://reactome.org/PathwayBrowser/#/R-HSA-392206 G alpha (i) inhibits adenylate cyclase IEA Homo sapiens 18420 R-HSA-4084989 https://reactome.org/PathwayBrowser/#/R-HSA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac TAS Homo sapiens 18420 R-HSA-426223 https://reactome.org/PathwayBrowser/#/R-HSA-426223 Cation influx mediated by TRPC3/6/7 TAS Homo sapiens 18420 R-HSA-429415 https://reactome.org/PathwayBrowser/#/R-HSA-429415 SYK binds to integrin alphaIIb beta3 TAS Homo sapiens 18420 R-HSA-429441 https://reactome.org/PathwayBrowser/#/R-HSA-429441 SYK activation by SRC TAS Homo sapiens 18420 R-HSA-432162 https://reactome.org/PathwayBrowser/#/R-HSA-432162 Unblocking of GRIN1:GRIN2 NMDA receptors IEA Homo sapiens 18420 R-HSA-432172 https://reactome.org/PathwayBrowser/#/R-HSA-432172 Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor IEA Homo sapiens 18420 R-HSA-442661 https://reactome.org/PathwayBrowser/#/R-HSA-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol TAS Homo sapiens 18420 R-HSA-449937 https://reactome.org/PathwayBrowser/#/R-HSA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] TAS Homo sapiens 18420 R-HSA-451152 https://reactome.org/PathwayBrowser/#/R-HSA-451152 MAP kinase p38 phosphorylates KSRP IEA Homo sapiens 18420 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 18420 R-HSA-5218804 https://reactome.org/PathwayBrowser/#/R-HSA-5218804 p38 MAPK activation by VEGFR TAS Homo sapiens 18420 R-HSA-5218826 https://reactome.org/PathwayBrowser/#/R-HSA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 TAS Homo sapiens 18420 R-HSA-5228992 https://reactome.org/PathwayBrowser/#/R-HSA-5228992 ROCK1,ROCK2 are activated TAS Homo sapiens 18420 R-HSA-5336453 https://reactome.org/PathwayBrowser/#/R-HSA-5336453 NIPAs transport Mg2+ from extracellular region to cytosol TAS Homo sapiens 18420 R-HSA-5336454 https://reactome.org/PathwayBrowser/#/R-HSA-5336454 MMGT1 transports Mg2+ from cytosol to Golgi lumen IEA Homo sapiens 18420 R-HSA-5336466 https://reactome.org/PathwayBrowser/#/R-HSA-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix TAS Homo sapiens 18420 R-HSA-5339528 https://reactome.org/PathwayBrowser/#/R-HSA-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol TAS Homo sapiens 18420 R-HSA-5339538 https://reactome.org/PathwayBrowser/#/R-HSA-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol TAS Homo sapiens 18420 R-HSA-5602901 https://reactome.org/PathwayBrowser/#/R-HSA-5602901 Defective GSS does not synthesize GSH TAS Homo sapiens 18420 R-HSA-5603087 https://reactome.org/PathwayBrowser/#/R-HSA-5603087 Defective MAT1A does not transfer Ado from ATP to L-Met TAS Homo sapiens 18420 R-HSA-5603114 https://reactome.org/PathwayBrowser/#/R-HSA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met TAS Homo sapiens 18420 R-HSA-5609939 https://reactome.org/PathwayBrowser/#/R-HSA-5609939 Defective PGM1 does not isomerise G6P to G1P TAS Homo sapiens 18420 R-HSA-5610727 https://reactome.org/PathwayBrowser/#/R-HSA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner TAS Homo sapiens 18420 R-HSA-5655835 https://reactome.org/PathwayBrowser/#/R-HSA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template TAS Homo sapiens 18420 R-HSA-5655892 https://reactome.org/PathwayBrowser/#/R-HSA-5655892 POLK incorporates dNMP opposite to damaged DNA base TAS Homo sapiens 18420 R-HSA-5655965 https://reactome.org/PathwayBrowser/#/R-HSA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini TAS Homo sapiens 18420 R-HSA-5656105 https://reactome.org/PathwayBrowser/#/R-HSA-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA TAS Homo sapiens 18420 R-HSA-5656148 https://reactome.org/PathwayBrowser/#/R-HSA-5656148 POLI incorporates dNMP opposite to damaged DNA base TAS Homo sapiens 18420 R-HSA-5656158 https://reactome.org/PathwayBrowser/#/R-HSA-5656158 POLZ elongates POLI-incorporated dNMP TAS Homo sapiens 18420 R-HSA-5672972 https://reactome.org/PathwayBrowser/#/R-HSA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex TAS Homo sapiens 18420 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 18420 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 18420 R-HSA-5672980 https://reactome.org/PathwayBrowser/#/R-HSA-5672980 Dissociation of RAS:RAF complex TAS Homo sapiens 18420 R-HSA-5694018 https://reactome.org/PathwayBrowser/#/R-HSA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate TAS Homo sapiens 18420 R-HSA-5696021 https://reactome.org/PathwayBrowser/#/R-HSA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P TAS Homo sapiens 18420 R-HSA-5696074 https://reactome.org/PathwayBrowser/#/R-HSA-5696074 AGK:Mg2+ phosphorylates MAG, DAG TAS Homo sapiens 18420 R-HSA-6786257 https://reactome.org/PathwayBrowser/#/R-HSA-6786257 DCTPP1 hydrolyses 5idCTP IEA Homo sapiens 18420 R-HSA-6787329 https://reactome.org/PathwayBrowser/#/R-HSA-6787329 PGM2:Mg2+ isomerises R1P to R5P TAS Homo sapiens 18420 R-HSA-6788295 https://reactome.org/PathwayBrowser/#/R-HSA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP TAS Homo sapiens 18420 R-HSA-6788597 https://reactome.org/PathwayBrowser/#/R-HSA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA TAS Homo sapiens 18420 R-HSA-6788912 https://reactome.org/PathwayBrowser/#/R-HSA-6788912 LHPP:Mg2+ dimer hydrolyses PPi TAS Homo sapiens 18420 R-HSA-6802910 https://reactome.org/PathwayBrowser/#/R-HSA-6802910 Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants TAS Homo sapiens 18420 R-HSA-6802911 https://reactome.org/PathwayBrowser/#/R-HSA-6802911 High kinase activity BRAF complexes phosphorylate MAP2Ks TAS Homo sapiens 18420 R-HSA-6802912 https://reactome.org/PathwayBrowser/#/R-HSA-6802912 High kinase activity BRAF mutants bind MAP2Ks and MAPKs TAS Homo sapiens 18420 R-HSA-6802914 https://reactome.org/PathwayBrowser/#/R-HSA-6802914 RAS:GTP:moderate kinase activity p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 18420 R-HSA-6802918 https://reactome.org/PathwayBrowser/#/R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants TAS Homo sapiens 18420 R-HSA-6802919 https://reactome.org/PathwayBrowser/#/R-HSA-6802919 RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 18420 R-HSA-6802921 https://reactome.org/PathwayBrowser/#/R-HSA-6802921 Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 18420 R-HSA-6802922 https://reactome.org/PathwayBrowser/#/R-HSA-6802922 Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS TAS Homo sapiens 18420 R-HSA-6802925 https://reactome.org/PathwayBrowser/#/R-HSA-6802925 Mutant RAS:p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 18420 R-HSA-6802926 https://reactome.org/PathwayBrowser/#/R-HSA-6802926 Mutant RAS:p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 18420 R-HSA-6802932 https://reactome.org/PathwayBrowser/#/R-HSA-6802932 Dissociation of BRAF/RAF fusion complex TAS Homo sapiens 18420 R-HSA-6802933 https://reactome.org/PathwayBrowser/#/R-HSA-6802933 p-BRAF and RAF fusion dimers phosphorylate MAP2Ks TAS Homo sapiens 18420 R-HSA-6802934 https://reactome.org/PathwayBrowser/#/R-HSA-6802934 p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs TAS Homo sapiens 18420 R-HSA-6802935 https://reactome.org/PathwayBrowser/#/R-HSA-6802935 MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers TAS Homo sapiens 18420 R-HSA-6802942 https://reactome.org/PathwayBrowser/#/R-HSA-6802942 RAS:GTP:p-RAF complexes paradoxically bind MAP2Ks and MAPKs TAS Homo sapiens 18420 R-HSA-6802943 https://reactome.org/PathwayBrowser/#/R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 18420 R-HSA-6803227 https://reactome.org/PathwayBrowser/#/R-HSA-6803227 Dissociation of high activity BRAF complexes TAS Homo sapiens 18420 R-HSA-6803230 https://reactome.org/PathwayBrowser/#/R-HSA-6803230 Dissociation of moderate activity BRAF complexes TAS Homo sapiens 18420 R-HSA-6803233 https://reactome.org/PathwayBrowser/#/R-HSA-6803233 Dissociation of oncogenic RAS:RAF complex TAS Homo sapiens 18420 R-HSA-6803234 https://reactome.org/PathwayBrowser/#/R-HSA-6803234 Dissociation of paradoxically activated RAS:BRAF complexes TAS Homo sapiens 18420 R-HSA-70349 https://reactome.org/PathwayBrowser/#/R-HSA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate TAS Homo sapiens 18420 R-HSA-70479 https://reactome.org/PathwayBrowser/#/R-HSA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P TAS Homo sapiens 18420 R-HSA-70486 https://reactome.org/PathwayBrowser/#/R-HSA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG TAS Homo sapiens 18420 R-HSA-70494 https://reactome.org/PathwayBrowser/#/R-HSA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG TAS Homo sapiens 18420 R-HSA-70997 https://reactome.org/PathwayBrowser/#/R-HSA-70997 SUCLG1/A2 cleaves succinyl-CoA TAS Homo sapiens 18420 R-HSA-71037 https://reactome.org/PathwayBrowser/#/R-HSA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ TAS Homo sapiens 18420 R-HSA-71181 https://reactome.org/PathwayBrowser/#/R-HSA-71181 FAH cleaves 4FAA TAS Homo sapiens 18420 R-HSA-71324 https://reactome.org/PathwayBrowser/#/R-HSA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 18420 R-HSA-71335 https://reactome.org/PathwayBrowser/#/R-HSA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate TAS Homo sapiens 18420 R-HSA-71401 https://reactome.org/PathwayBrowser/#/R-HSA-71401 OGDH dimer decarboxylates 2-OG TAS Homo sapiens 18420 R-HSA-71660 https://reactome.org/PathwayBrowser/#/R-HSA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O TAS Homo sapiens 18420 R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 18420 R-HSA-71732 https://reactome.org/PathwayBrowser/#/R-HSA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate TAS Homo sapiens 18420 R-HSA-71775 https://reactome.org/PathwayBrowser/#/R-HSA-71775 SUCLG1/G2 cleaves succinyl-CoA TAS Homo sapiens 18420 R-HSA-71850 https://reactome.org/PathwayBrowser/#/R-HSA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP TAS Homo sapiens 18420 R-HSA-73598 https://reactome.org/PathwayBrowser/#/R-HSA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) TAS Homo sapiens 18420 R-HSA-73605 https://reactome.org/PathwayBrowser/#/R-HSA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate TAS Homo sapiens 18420 R-HSA-74215 https://reactome.org/PathwayBrowser/#/R-HSA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 18420 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 18420 R-HSA-74948 https://reactome.org/PathwayBrowser/#/R-HSA-74948 PP2A dephosphorylates p-RHO to RHO TAS Homo sapiens 18420 R-HSA-8850846 https://reactome.org/PathwayBrowser/#/R-HSA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates TAS Homo sapiens 18420 R-HSA-8850854 https://reactome.org/PathwayBrowser/#/R-HSA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates TAS Homo sapiens 18420 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 18420 R-HSA-8851110 https://reactome.org/PathwayBrowser/#/R-HSA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates TAS Homo sapiens 18420 R-HSA-8851129 https://reactome.org/PathwayBrowser/#/R-HSA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates TAS Homo sapiens 18420 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 18420 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 18420 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 18420 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 18420 R-HSA-8939959 https://reactome.org/PathwayBrowser/#/R-HSA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ TAS Homo sapiens 18420 R-HSA-8953499 https://reactome.org/PathwayBrowser/#/R-HSA-8953499 IMPAD1 hydrolyses PAP to AMP TAS Homo sapiens 18420 R-HSA-8955760 https://reactome.org/PathwayBrowser/#/R-HSA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP TAS Homo sapiens 18420 R-HSA-8955794 https://reactome.org/PathwayBrowser/#/R-HSA-8955794 PGP:Mg2+ dimer hydrolyses 3PG to glycerol IEA Homo sapiens 18420 R-HSA-8982667 https://reactome.org/PathwayBrowser/#/R-HSA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P TAS Homo sapiens 18420 R-HSA-9012016 https://reactome.org/PathwayBrowser/#/R-HSA-9012016 FAHD1 dimer hydrolyses OA to PYR TAS Homo sapiens 18420 R-HSA-9012036 https://reactome.org/PathwayBrowser/#/R-HSA-9012036 ME1 tetramer decarboxylates MAL to PYR TAS Homo sapiens 18420 R-HSA-9012268 https://reactome.org/PathwayBrowser/#/R-HSA-9012268 ME2 tetramer decarboxylates MAL to PYR TAS Homo sapiens 18420 R-HSA-9012349 https://reactome.org/PathwayBrowser/#/R-HSA-9012349 ME3 tetramer decarboxylates MAL to PYR TAS Homo sapiens 18420 R-HSA-9014741 https://reactome.org/PathwayBrowser/#/R-HSA-9014741 PXLP-K56-SRR dimer deaminates D-Ser TAS Homo sapiens 18420 R-HSA-9014766 https://reactome.org/PathwayBrowser/#/R-HSA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser TAS Homo sapiens 18420 R-HSA-9024993 https://reactome.org/PathwayBrowser/#/R-HSA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 TAS Homo sapiens 18420 R-HSA-936883 https://reactome.org/PathwayBrowser/#/R-HSA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen TAS Homo sapiens 18420 R-HSA-947531 https://reactome.org/PathwayBrowser/#/R-HSA-947531 Molybdenum ion transfer onto molybdopterin TAS Homo sapiens 18420 R-HSA-9614185 https://reactome.org/PathwayBrowser/#/R-HSA-9614185 Mg2+ binds GRIN1:GRIN2 NMDA receptors IEA Homo sapiens 18420 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 18420 R-HSA-9621179 https://reactome.org/PathwayBrowser/#/R-HSA-9621179 Cinaciguat binds sGC:NO TAS Homo sapiens 18420 R-HSA-9638125 https://reactome.org/PathwayBrowser/#/R-HSA-9638125 PGM1:Mg2+ isomerises G1P to G6P TAS Homo sapiens 18420 R-HSA-9638127 https://reactome.org/PathwayBrowser/#/R-HSA-9638127 PGM1:Mg2+ isomerises G6P to G1P TAS Homo sapiens 18420 R-HSA-9639567 https://reactome.org/PathwayBrowser/#/R-HSA-9639567 NPAS4 gene transcription is repressed by KCNIP3 IEA Homo sapiens 18420 R-HSA-9640060 https://reactome.org/PathwayBrowser/#/R-HSA-9640060 KCNIP3 binds NPAS4 gene promoter IEA Homo sapiens 18420 R-HSA-9640063 https://reactome.org/PathwayBrowser/#/R-HSA-9640063 Ca2+ binds KCNIP3 IEA Homo sapiens 18420 R-HSA-965067 https://reactome.org/PathwayBrowser/#/R-HSA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP TAS Homo sapiens 18420 R-HSA-9650858 https://reactome.org/PathwayBrowser/#/R-HSA-9650858 Meglitinides bind ABCC8 TAS Homo sapiens 18420 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 18420 R-HSA-9656209 https://reactome.org/PathwayBrowser/#/R-HSA-9656209 Dissociation of RAS:RAF1 mutant complex TAS Homo sapiens 18420 R-HSA-9656211 https://reactome.org/PathwayBrowser/#/R-HSA-9656211 MAP2Ks and MAPKs bind to the activated mutant RAF1 complex TAS Homo sapiens 18420 R-HSA-9656214 https://reactome.org/PathwayBrowser/#/R-HSA-9656214 MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants TAS Homo sapiens 18420 R-HSA-9656215 https://reactome.org/PathwayBrowser/#/R-HSA-9656215 RAF1 mutant complexes phosphorylate MAP2K dimer TAS Homo sapiens 18420 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 18420 R-HSA-9657603 https://reactome.org/PathwayBrowser/#/R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs TAS Homo sapiens 18420 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 18420 R-HSA-9657608 https://reactome.org/PathwayBrowser/#/R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK TAS Homo sapiens 18420 R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 18420 R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 18420 R-HSA-9694344 https://reactome.org/PathwayBrowser/#/R-HSA-9694344 Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching IEA Homo sapiens 18420 R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 18420 R-HSA-9694445 https://reactome.org/PathwayBrowser/#/R-HSA-9694445 nsp16 binds nsp10 TAS Homo sapiens 18420 R-HSA-9694454 https://reactome.org/PathwayBrowser/#/R-HSA-9694454 Replication transcription complex binds SARS-CoV-2 genomic RNA TAS Homo sapiens 18420 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 18420 R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 18420 R-HSA-9694495 https://reactome.org/PathwayBrowser/#/R-HSA-9694495 RTC binds SARS-CoV-2 genomic RNA complement (minus strand) IEA Homo sapiens 18420 R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 18420 R-HSA-9694506 https://reactome.org/PathwayBrowser/#/R-HSA-9694506 Synthesis of SARS-CoV-2 plus strand subgenomic mRNAs TAS Homo sapiens 18420 R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 18420 R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 18420 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 18420 R-HSA-9694576 https://reactome.org/PathwayBrowser/#/R-HSA-9694576 nsp3 binds to nsp7-8 and nsp12-16 IEA Homo sapiens 18420 R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 18420 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 18420 R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 18420 R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 18420 R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 18420 R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 18420 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 18420 R-HSA-9712183 https://reactome.org/PathwayBrowser/#/R-HSA-9712183 ADCY3:GNAL:GTP converts ATP to cAMP IEA Homo sapiens 18420 R-HSA-9712187 https://reactome.org/PathwayBrowser/#/R-HSA-9712187 GNAL:GTP (G alpha-olf) binds ADCY3 IEA Homo sapiens 18420 R-HSA-9717830 https://reactome.org/PathwayBrowser/#/R-HSA-9717830 GGPS1 hexamer transfers IPPP to GPP TAS Homo sapiens 18420 R-HSA-9717834 https://reactome.org/PathwayBrowser/#/R-HSA-9717834 GGPS1 hexamer transfers IPPP to DMAPP TAS Homo sapiens 18420 R-HSA-9717841 https://reactome.org/PathwayBrowser/#/R-HSA-9717841 holo-FDPS dimer binds NBPs TAS Homo sapiens 18420 R-HSA-9729330 https://reactome.org/PathwayBrowser/#/R-HSA-9729330 SRPK1/2 phosphorylates nucleoprotein TAS Homo sapiens 18420 R-HSA-9731228 https://reactome.org/PathwayBrowser/#/R-HSA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP TAS Homo sapiens 18420 R-HSA-9731590 https://reactome.org/PathwayBrowser/#/R-HSA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP TAS Homo sapiens 18420 R-HSA-9731613 https://reactome.org/PathwayBrowser/#/R-HSA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP TAS Homo sapiens 18420 R-HSA-9731632 https://reactome.org/PathwayBrowser/#/R-HSA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP TAS Homo sapiens 18420 R-HSA-9734274 https://reactome.org/PathwayBrowser/#/R-HSA-9734274 Defective HPRT1 does not convert guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 18420 R-HSA-9748951 https://reactome.org/PathwayBrowser/#/R-HSA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP TAS Homo sapiens 18420 R-HSA-9754745 https://reactome.org/PathwayBrowser/#/R-HSA-9754745 IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 18420 R-HSA-9754916 https://reactome.org/PathwayBrowser/#/R-HSA-9754916 NT5C2 tetramer phosphorylates RBV TAS Homo sapiens 18420 R-HSA-9754974 https://reactome.org/PathwayBrowser/#/R-HSA-9754974 ADK phosphorylates RBV TAS Homo sapiens 18420 R-HSA-9755078 https://reactome.org/PathwayBrowser/#/R-HSA-9755078 NT5C2 tetramer dephosphorylates RBV-MP TAS Homo sapiens 18420 R-HSA-9755252 https://reactome.org/PathwayBrowser/#/R-HSA-9755252 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 18420 R-HSA-9755258 https://reactome.org/PathwayBrowser/#/R-HSA-9755258 DDX58 binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 18420 R-HSA-9759709 https://reactome.org/PathwayBrowser/#/R-HSA-9759709 CNBP binds SARS-CoV-2 G-rich RNA TAS Homo sapiens 18420 R-HSA-9760510 https://reactome.org/PathwayBrowser/#/R-HSA-9760510 LARP1 binds SARS-CoV-2 RNA TAS Homo sapiens 18420 R-HSA-9761852 https://reactome.org/PathwayBrowser/#/R-HSA-9761852 NFE2L2-dependent TKT gene expression TAS Homo sapiens 18420 R-HSA-9761854 https://reactome.org/PathwayBrowser/#/R-HSA-9761854 NFE2L2-dependent ME1 gene expression TAS Homo sapiens 18420 R-HSA-9770131 https://reactome.org/PathwayBrowser/#/R-HSA-9770131 Formation of the Spliceosomal B* complex TAS Homo sapiens 18420 R-HSA-9770141 https://reactome.org/PathwayBrowser/#/R-HSA-9770141 Formation of the Spliceosomal C* complex TAS Homo sapiens 18420 R-HSA-9770145 https://reactome.org/PathwayBrowser/#/R-HSA-9770145 Formation of the Spliceosomal Bact complex TAS Homo sapiens 18420 R-HSA-9770236 https://reactome.org/PathwayBrowser/#/R-HSA-9770236 Formation of the Spliceosomal P complex and exon ligation TAS Homo sapiens 18420 R-HSA-9770847 https://reactome.org/PathwayBrowser/#/R-HSA-9770847 Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) TAS Homo sapiens 18420 R-HSA-9772351 https://reactome.org/PathwayBrowser/#/R-HSA-9772351 Disassembly of the Intron Lariat Spliceosome (new) TAS Homo sapiens 18420 R-HSA-977324 https://reactome.org/PathwayBrowser/#/R-HSA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser TAS Homo sapiens 18420 R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 18420 R-HSA-9821967 https://reactome.org/PathwayBrowser/#/R-HSA-9821967 SRPK1 phosphorylates PRM2 in PRM2:dsDNA IEA Homo sapiens 18420 R-HSA-9821982 https://reactome.org/PathwayBrowser/#/R-HSA-9821982 SRPK1 phosphorylates PRM1 in PRM1:dsDNA IEA Homo sapiens 18420 R-HSA-9828639 https://reactome.org/PathwayBrowser/#/R-HSA-9828639 Transcription of respiratory syncytial virus subgenomic positive sense mRNAs TAS Homo sapiens 18420 R-HSA-9830236 https://reactome.org/PathwayBrowser/#/R-HSA-9830236 Protein P tetramer binds protein L TAS Homo sapiens 18420 R-HSA-9830284 https://reactome.org/PathwayBrowser/#/R-HSA-9830284 Protein M2-1 tetramers bind protein P tetramer TAS Homo sapiens 18420 R-HSA-9830848 https://reactome.org/PathwayBrowser/#/R-HSA-9830848 L protein acts as a cap N7 methyltransferase to modify RSV mRNAs TAS Homo sapiens 18420 R-HSA-9831485 https://reactome.org/PathwayBrowser/#/R-HSA-9831485 Nascent L binds Mg2+ TAS Homo sapiens 18420 R-HSA-983153 https://reactome.org/PathwayBrowser/#/R-HSA-983153 E1 mediated ubiquitin activation TAS Homo sapiens 18420 R-HSA-9833031 https://reactome.org/PathwayBrowser/#/R-HSA-9833031 Polyadenylation of respiratory syncytial virus subgenomic positive-sense mRNAs TAS Homo sapiens 18420 R-HSA-9833933 https://reactome.org/PathwayBrowser/#/R-HSA-9833933 RdRP binds hRSV nucleocapsid TAS Homo sapiens 18420 R-HSA-9834003 https://reactome.org/PathwayBrowser/#/R-HSA-9834003 L protein acts as a cap 2'-O-methyltransferase to modify RSV mRNAs TAS Homo sapiens 18420 R-HSA-9834719 https://reactome.org/PathwayBrowser/#/R-HSA-9834719 Synthesis of negative sense genomic RNA of respiratory syncytial virus TAS Homo sapiens 18420 R-HSA-9834736 https://reactome.org/PathwayBrowser/#/R-HSA-9834736 Synthesis of antigenomic RNA of human respiratory syncytial virus TAS Homo sapiens 18420 R-HSA-9835151 https://reactome.org/PathwayBrowser/#/R-HSA-9835151 Packaging of RdRP complex with replicated hRSV A nucleocapsid TAS Homo sapiens 18420 R-HSA-9835165 https://reactome.org/PathwayBrowser/#/R-HSA-9835165 Formation of hRSV A matrix lattice TAS Homo sapiens 18420 R-HSA-9835171 https://reactome.org/PathwayBrowser/#/R-HSA-9835171 Budding of hRSV A virions from infected cell TAS Homo sapiens 18420 R-HSA-9836227 https://reactome.org/PathwayBrowser/#/R-HSA-9836227 RSV F binds TLR4:LY96:CD14 TAS Homo sapiens 18420 R-HSA-9836467 https://reactome.org/PathwayBrowser/#/R-HSA-9836467 F protein binds NCL on host cell surface TAS Homo sapiens 18420 R-HSA-9836468 https://reactome.org/PathwayBrowser/#/R-HSA-9836468 G protein binds CX3CR1 on host cell surface TAS Homo sapiens 18420 R-HSA-9837376 https://reactome.org/PathwayBrowser/#/R-HSA-9837376 RSV G binds CD209,CLEC4M TAS Homo sapiens 18420 R-HSA-9837392 https://reactome.org/PathwayBrowser/#/R-HSA-9837392 Packaging of antigenomic RNA of human respiratory syncytial virus TAS Homo sapiens 18420 R-HSA-9837511 https://reactome.org/PathwayBrowser/#/R-HSA-9837511 Abortive replication of hRSV A TAS Homo sapiens 18420 R-HSA-9837543 https://reactome.org/PathwayBrowser/#/R-HSA-9837543 hRSV A enters host cell through membrane fusion TAS Homo sapiens 18420 R-HSA-9837625 https://reactome.org/PathwayBrowser/#/R-HSA-9837625 hRSV A enters host cell through macropinocytosis TAS Homo sapiens 18420 R-HSA-9837707 https://reactome.org/PathwayBrowser/#/R-HSA-9837707 Release of hRSV A nucleocapsid from macropinosome TAS Homo sapiens 18420 R-HSA-9845143 https://reactome.org/PathwayBrowser/#/R-HSA-9845143 F inhibitors bind F on RSV virion TAS Homo sapiens 18420 R-HSA-9845222 https://reactome.org/PathwayBrowser/#/R-HSA-9845222 Lumicitabine binds RdRP on nucleocapsid TAS Homo sapiens 18420 R-HSA-9853499 https://reactome.org/PathwayBrowser/#/R-HSA-9853499 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 18420 R-HSA-9853512 https://reactome.org/PathwayBrowser/#/R-HSA-9853512 DLST transfers succinyl to CoA TAS Homo sapiens 18420 R-HSA-9861616 https://reactome.org/PathwayBrowser/#/R-HSA-9861616 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 18420 R-HSA-9861631 https://reactome.org/PathwayBrowser/#/R-HSA-9861631 ME1 tetramerizes TAS Homo sapiens 18420 R-HSA-9861642 https://reactome.org/PathwayBrowser/#/R-HSA-9861642 NEK1 phosphorylates ME1 TAS Homo sapiens 18420 R-HSA-9861660 https://reactome.org/PathwayBrowser/#/R-HSA-9861660 ME1 tetramer decarboxylates OA to PYR TAS Homo sapiens 18420 R-HSA-9861667 https://reactome.org/PathwayBrowser/#/R-HSA-9861667 DLAT trimer transfers acetyl to CoA TAS Homo sapiens 18420 R-HSA-9861734 https://reactome.org/PathwayBrowser/#/R-HSA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT TAS Homo sapiens 18420 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 18420 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 18420 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 18420 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 18420 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 18420 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 18420 R-MMU-109624 https://reactome.org/PathwayBrowser/#/R-MMU-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Mus musculus 18420 R-MMU-109671 https://reactome.org/PathwayBrowser/#/R-MMU-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Mus musculus 18420 R-MMU-111215 https://reactome.org/PathwayBrowser/#/R-MMU-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Mus musculus 18420 R-MMU-111519 https://reactome.org/PathwayBrowser/#/R-MMU-111519 inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate TAS Mus musculus 18420 R-MMU-111524 https://reactome.org/PathwayBrowser/#/R-MMU-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Mus musculus 18420 R-MMU-111930 https://reactome.org/PathwayBrowser/#/R-MMU-111930 Adenylate cyclase produces cAMP IEA Mus musculus 18420 R-MMU-1237129 https://reactome.org/PathwayBrowser/#/R-MMU-1237129 Acireductone is created IEA Mus musculus 18420 R-MMU-1482961 https://reactome.org/PathwayBrowser/#/R-MMU-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Mus musculus 18420 R-MMU-1482962 https://reactome.org/PathwayBrowser/#/R-MMU-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Mus musculus 18420 R-MMU-1482973 https://reactome.org/PathwayBrowser/#/R-MMU-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Mus musculus 18420 R-MMU-1482976 https://reactome.org/PathwayBrowser/#/R-MMU-1482976 CDP-DAG is converted to PI by CDIPT IEA Mus musculus 18420 R-MMU-1483096 https://reactome.org/PathwayBrowser/#/R-MMU-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Mus musculus 18420 R-MMU-1483121 https://reactome.org/PathwayBrowser/#/R-MMU-1483121 PA is converted to CDP-DAG by CDS1 IEA Mus musculus 18420 R-MMU-1483159 https://reactome.org/PathwayBrowser/#/R-MMU-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Mus musculus 18420 R-MMU-1483203 https://reactome.org/PathwayBrowser/#/R-MMU-1483203 PA is dephosphorylated to DAG by LPIN IEA Mus musculus 18420 R-MMU-1606273 https://reactome.org/PathwayBrowser/#/R-MMU-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Mus musculus 18420 R-MMU-1606288 https://reactome.org/PathwayBrowser/#/R-MMU-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Mus musculus 18420 R-MMU-163741 https://reactome.org/PathwayBrowser/#/R-MMU-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Mus musculus 18420 R-MMU-163751 https://reactome.org/PathwayBrowser/#/R-MMU-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Mus musculus 18420 R-MMU-1675928 https://reactome.org/PathwayBrowser/#/R-MMU-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Mus musculus 18420 R-MMU-1675939 https://reactome.org/PathwayBrowser/#/R-MMU-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Mus musculus 18420 R-MMU-1675961 https://reactome.org/PathwayBrowser/#/R-MMU-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Mus musculus 18420 R-MMU-1676024 https://reactome.org/PathwayBrowser/#/R-MMU-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Mus musculus 18420 R-MMU-1676109 https://reactome.org/PathwayBrowser/#/R-MMU-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Mus musculus 18420 R-MMU-1676206 https://reactome.org/PathwayBrowser/#/R-MMU-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Mus musculus 18420 R-MMU-170666 https://reactome.org/PathwayBrowser/#/R-MMU-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Mus musculus 18420 R-MMU-170671 https://reactome.org/PathwayBrowser/#/R-MMU-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Mus musculus 18420 R-MMU-170672 https://reactome.org/PathwayBrowser/#/R-MMU-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Mus musculus 18420 R-MMU-170674 https://reactome.org/PathwayBrowser/#/R-MMU-170674 Dissociation of the Gi alpha:G olf complex IEA Mus musculus 18420 R-MMU-170676 https://reactome.org/PathwayBrowser/#/R-MMU-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Mus musculus 18420 R-MMU-170677 https://reactome.org/PathwayBrowser/#/R-MMU-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Mus musculus 18420 R-MMU-170685 https://reactome.org/PathwayBrowser/#/R-MMU-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Mus musculus 18420 R-MMU-170686 https://reactome.org/PathwayBrowser/#/R-MMU-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Mus musculus 18420 R-MMU-174391 https://reactome.org/PathwayBrowser/#/R-MMU-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Mus musculus 18420 R-MMU-174394 https://reactome.org/PathwayBrowser/#/R-MMU-174394 GSS:Mg2+ dimer synthesizes GSH IEA Mus musculus 18420 R-MMU-1855154 https://reactome.org/PathwayBrowser/#/R-MMU-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 18420 R-MMU-1855159 https://reactome.org/PathwayBrowser/#/R-MMU-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Mus musculus 18420 R-MMU-1855162 https://reactome.org/PathwayBrowser/#/R-MMU-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Mus musculus 18420 R-MMU-1855165 https://reactome.org/PathwayBrowser/#/R-MMU-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 18420 R-MMU-1855166 https://reactome.org/PathwayBrowser/#/R-MMU-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Mus musculus 18420 R-MMU-1855169 https://reactome.org/PathwayBrowser/#/R-MMU-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Mus musculus 18420 R-MMU-1855171 https://reactome.org/PathwayBrowser/#/R-MMU-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Mus musculus 18420 R-MMU-1855172 https://reactome.org/PathwayBrowser/#/R-MMU-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Mus musculus 18420 R-MMU-1855197 https://reactome.org/PathwayBrowser/#/R-MMU-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Mus musculus 18420 R-MMU-1855198 https://reactome.org/PathwayBrowser/#/R-MMU-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 18420 R-MMU-1855205 https://reactome.org/PathwayBrowser/#/R-MMU-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Mus musculus 18420 R-MMU-1855208 https://reactome.org/PathwayBrowser/#/R-MMU-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Mus musculus 18420 R-MMU-1855210 https://reactome.org/PathwayBrowser/#/R-MMU-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 18420 R-MMU-1855211 https://reactome.org/PathwayBrowser/#/R-MMU-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 18420 R-MMU-1855218 https://reactome.org/PathwayBrowser/#/R-MMU-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Mus musculus 18420 R-MMU-1855219 https://reactome.org/PathwayBrowser/#/R-MMU-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Mus musculus 18420 R-MMU-1855232 https://reactome.org/PathwayBrowser/#/R-MMU-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Mus musculus 18420 R-MMU-187688 https://reactome.org/PathwayBrowser/#/R-MMU-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Mus musculus 18420 R-MMU-191303 https://reactome.org/PathwayBrowser/#/R-MMU-191303 FDPS dimer transfers IPPP to GPP IEA Mus musculus 18420 R-MMU-191322 https://reactome.org/PathwayBrowser/#/R-MMU-191322 FDPS dimer transfers IPPP to DMAPP IEA Mus musculus 18420 R-MMU-191382 https://reactome.org/PathwayBrowser/#/R-MMU-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Mus musculus 18420 R-MMU-191402 https://reactome.org/PathwayBrowser/#/R-MMU-191402 Reduction of presqualene diphosphate to form squalene IEA Mus musculus 18420 R-MMU-191405 https://reactome.org/PathwayBrowser/#/R-MMU-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Mus musculus 18420 R-MMU-196761 https://reactome.org/PathwayBrowser/#/R-MMU-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Mus musculus 18420 R-MMU-196964 https://reactome.org/PathwayBrowser/#/R-MMU-196964 RFK:Mg2+ phosphorylates RIB IEA Mus musculus 18420 R-MMU-197186 https://reactome.org/PathwayBrowser/#/R-MMU-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Mus musculus 18420 R-MMU-197235 https://reactome.org/PathwayBrowser/#/R-MMU-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 18420 R-MMU-200474 https://reactome.org/PathwayBrowser/#/R-MMU-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 18420 R-MMU-2023971 https://reactome.org/PathwayBrowser/#/R-MMU-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 18420 R-MMU-2023973 https://reactome.org/PathwayBrowser/#/R-MMU-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 18420 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 18420 R-MMU-204169 https://reactome.org/PathwayBrowser/#/R-MMU-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Mus musculus 18420 R-MMU-2046085 https://reactome.org/PathwayBrowser/#/R-MMU-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Mus musculus 18420 R-MMU-2046098 https://reactome.org/PathwayBrowser/#/R-MMU-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Mus musculus 18420 R-MMU-216043 https://reactome.org/PathwayBrowser/#/R-MMU-216043 Collagen type II binds integrin alpha10beta1 IEA Mus musculus 18420 R-MMU-216045 https://reactome.org/PathwayBrowser/#/R-MMU-216045 Collagen type I binds integrin alpha11beta1 IEA Mus musculus 18420 R-MMU-216069 https://reactome.org/PathwayBrowser/#/R-MMU-216069 Interaction of integrin alphaDbeta2 with fibrin IEA Mus musculus 18420 R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Mus musculus 18420 R-MMU-2162066 https://reactome.org/PathwayBrowser/#/R-MMU-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Mus musculus 18420 R-MMU-2162253 https://reactome.org/PathwayBrowser/#/R-MMU-2162253 PDSS1,2 ligates FPP to IPPP IEA Mus musculus 18420 R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 18420 R-MMU-2393939 https://reactome.org/PathwayBrowser/#/R-MMU-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 18420 R-MMU-2393954 https://reactome.org/PathwayBrowser/#/R-MMU-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 18420 R-MMU-2395818 https://reactome.org/PathwayBrowser/#/R-MMU-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Mus musculus 18420 R-MMU-2395849 https://reactome.org/PathwayBrowser/#/R-MMU-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 18420 R-MMU-2395872 https://reactome.org/PathwayBrowser/#/R-MMU-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Mus musculus 18420 R-MMU-2408505 https://reactome.org/PathwayBrowser/#/R-MMU-2408505 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by Pstk TAS Mus musculus 18420 R-MMU-2408551 https://reactome.org/PathwayBrowser/#/R-MMU-2408551 SeMet is converted to AdoSeMet by MAT IEA Mus musculus 18420 R-MMU-2509793 https://reactome.org/PathwayBrowser/#/R-MMU-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Mus musculus 18420 R-MMU-2509816 https://reactome.org/PathwayBrowser/#/R-MMU-2509816 NUDT16 hydrolyses IDP to IMP IEA Mus musculus 18420 R-MMU-2509827 https://reactome.org/PathwayBrowser/#/R-MMU-2509827 ITPA hydrolyses ITP to IMP IEA Mus musculus 18420 R-MMU-2509831 https://reactome.org/PathwayBrowser/#/R-MMU-2509831 ITPA hydrolyses XTP to XMP IEA Mus musculus 18420 R-MMU-2509838 https://reactome.org/PathwayBrowser/#/R-MMU-2509838 ITPA hydrolyses dITP to dIMP IEA Mus musculus 18420 R-MMU-265682 https://reactome.org/PathwayBrowser/#/R-MMU-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Mus musculus 18420 R-MMU-3322001 https://reactome.org/PathwayBrowser/#/R-MMU-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Mus musculus 18420 R-MMU-3322003 https://reactome.org/PathwayBrowser/#/R-MMU-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Mus musculus 18420 R-MMU-3322005 https://reactome.org/PathwayBrowser/#/R-MMU-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Mus musculus 18420 R-MMU-3322025 https://reactome.org/PathwayBrowser/#/R-MMU-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Mus musculus 18420 R-MMU-3322041 https://reactome.org/PathwayBrowser/#/R-MMU-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Mus musculus 18420 R-MMU-3322057 https://reactome.org/PathwayBrowser/#/R-MMU-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Mus musculus 18420 R-MMU-354066 https://reactome.org/PathwayBrowser/#/R-MMU-354066 Translocation of PTK2 to Focal complexes IEA Mus musculus 18420 R-MMU-354073 https://reactome.org/PathwayBrowser/#/R-MMU-354073 Autophosphorylation of PTK2 at Y397 IEA Mus musculus 18420 R-MMU-354087 https://reactome.org/PathwayBrowser/#/R-MMU-354087 Recruitment of GRB2 to p-PTK2 IEA Mus musculus 18420 R-MMU-354124 https://reactome.org/PathwayBrowser/#/R-MMU-354124 Phosphorylation of pPTK2 by SRC IEA Mus musculus 18420 R-MMU-354149 https://reactome.org/PathwayBrowser/#/R-MMU-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Mus musculus 18420 R-MMU-354165 https://reactome.org/PathwayBrowser/#/R-MMU-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Mus musculus 18420 R-MMU-372693 https://reactome.org/PathwayBrowser/#/R-MMU-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Mus musculus 18420 R-MMU-372697 https://reactome.org/PathwayBrowser/#/R-MMU-372697 Crk binding to p130cas IEA Mus musculus 18420 R-MMU-372705 https://reactome.org/PathwayBrowser/#/R-MMU-372705 Recruitment of BCAR1 to PTK2 complex IEA Mus musculus 18420 R-MMU-377640 https://reactome.org/PathwayBrowser/#/R-MMU-377640 Autophosphorylation of SRC IEA Mus musculus 18420 R-MMU-377641 https://reactome.org/PathwayBrowser/#/R-MMU-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Mus musculus 18420 R-MMU-377643 https://reactome.org/PathwayBrowser/#/R-MMU-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Mus musculus 18420 R-MMU-377644 https://reactome.org/PathwayBrowser/#/R-MMU-377644 Release of CSK from SRC IEA Mus musculus 18420 R-MMU-3781018 https://reactome.org/PathwayBrowser/#/R-MMU-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Mus musculus 18420 R-MMU-3781023 https://reactome.org/PathwayBrowser/#/R-MMU-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Mus musculus 18420 R-MMU-3781024 https://reactome.org/PathwayBrowser/#/R-MMU-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Mus musculus 18420 R-MMU-3858495 https://reactome.org/PathwayBrowser/#/R-MMU-3858495 DAAM1 recruits GTP-bound RHOA IEA Mus musculus 18420 R-MMU-389611 https://reactome.org/PathwayBrowser/#/R-MMU-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Mus musculus 18420 R-MMU-392064 https://reactome.org/PathwayBrowser/#/R-MMU-392064 G alpha (z) inhibits adenylate cyclase IEA Mus musculus 18420 R-MMU-4084989 https://reactome.org/PathwayBrowser/#/R-MMU-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Mus musculus 18420 R-MMU-426223 https://reactome.org/PathwayBrowser/#/R-MMU-426223 Cation influx mediated by TRPC3/6/7 IEA Mus musculus 18420 R-MMU-429415 https://reactome.org/PathwayBrowser/#/R-MMU-429415 SYK binds to integrin alphaIIb beta3 IEA Mus musculus 18420 R-MMU-429441 https://reactome.org/PathwayBrowser/#/R-MMU-429441 SYK activation by SRC IEA Mus musculus 18420 R-MMU-442661 https://reactome.org/PathwayBrowser/#/R-MMU-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol IEA Mus musculus 18420 R-MMU-449937 https://reactome.org/PathwayBrowser/#/R-MMU-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Mus musculus 18420 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 18420 R-MMU-5218804 https://reactome.org/PathwayBrowser/#/R-MMU-5218804 p38 MAPK activation by VEGFR IEA Mus musculus 18420 R-MMU-5218826 https://reactome.org/PathwayBrowser/#/R-MMU-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Mus musculus 18420 R-MMU-5228992 https://reactome.org/PathwayBrowser/#/R-MMU-5228992 ROCK1,ROCK2 are activated IEA Mus musculus 18420 R-MMU-5336430 https://reactome.org/PathwayBrowser/#/R-MMU-5336430 Mmgt1,2 transport Mg2+ from cytosol to Golgi lumen TAS Mus musculus 18420 R-MMU-5336453 https://reactome.org/PathwayBrowser/#/R-MMU-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Mus musculus 18420 R-MMU-5336466 https://reactome.org/PathwayBrowser/#/R-MMU-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Mus musculus 18420 R-MMU-5339528 https://reactome.org/PathwayBrowser/#/R-MMU-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Mus musculus 18420 R-MMU-5339538 https://reactome.org/PathwayBrowser/#/R-MMU-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Mus musculus 18420 R-MMU-5603114 https://reactome.org/PathwayBrowser/#/R-MMU-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Mus musculus 18420 R-MMU-5610727 https://reactome.org/PathwayBrowser/#/R-MMU-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Mus musculus 18420 R-MMU-5655835 https://reactome.org/PathwayBrowser/#/R-MMU-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Mus musculus 18420 R-MMU-5655892 https://reactome.org/PathwayBrowser/#/R-MMU-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Mus musculus 18420 R-MMU-5655965 https://reactome.org/PathwayBrowser/#/R-MMU-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Mus musculus 18420 R-MMU-5656105 https://reactome.org/PathwayBrowser/#/R-MMU-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Mus musculus 18420 R-MMU-5656148 https://reactome.org/PathwayBrowser/#/R-MMU-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Mus musculus 18420 R-MMU-5656158 https://reactome.org/PathwayBrowser/#/R-MMU-5656158 POLZ elongates POLI-incorporated dNMP IEA Mus musculus 18420 R-MMU-5672972 https://reactome.org/PathwayBrowser/#/R-MMU-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Mus musculus 18420 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 18420 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 18420 R-MMU-5672980 https://reactome.org/PathwayBrowser/#/R-MMU-5672980 Dissociation of RAS:RAF complex IEA Mus musculus 18420 R-MMU-5694018 https://reactome.org/PathwayBrowser/#/R-MMU-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Mus musculus 18420 R-MMU-5696021 https://reactome.org/PathwayBrowser/#/R-MMU-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Mus musculus 18420 R-MMU-5696074 https://reactome.org/PathwayBrowser/#/R-MMU-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Mus musculus 18420 R-MMU-6786295 https://reactome.org/PathwayBrowser/#/R-MMU-6786295 Dctpp1 hydrolyses 5idCTP TAS Mus musculus 18420 R-MMU-6787329 https://reactome.org/PathwayBrowser/#/R-MMU-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Mus musculus 18420 R-MMU-6788295 https://reactome.org/PathwayBrowser/#/R-MMU-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Mus musculus 18420 R-MMU-6788597 https://reactome.org/PathwayBrowser/#/R-MMU-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Mus musculus 18420 R-MMU-6788912 https://reactome.org/PathwayBrowser/#/R-MMU-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Mus musculus 18420 R-MMU-70349 https://reactome.org/PathwayBrowser/#/R-MMU-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Mus musculus 18420 R-MMU-70479 https://reactome.org/PathwayBrowser/#/R-MMU-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Mus musculus 18420 R-MMU-70486 https://reactome.org/PathwayBrowser/#/R-MMU-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Mus musculus 18420 R-MMU-70494 https://reactome.org/PathwayBrowser/#/R-MMU-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Mus musculus 18420 R-MMU-70997 https://reactome.org/PathwayBrowser/#/R-MMU-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Mus musculus 18420 R-MMU-71037 https://reactome.org/PathwayBrowser/#/R-MMU-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Mus musculus 18420 R-MMU-71181 https://reactome.org/PathwayBrowser/#/R-MMU-71181 FAH cleaves 4FAA IEA Mus musculus 18420 R-MMU-71324 https://reactome.org/PathwayBrowser/#/R-MMU-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 18420 R-MMU-71335 https://reactome.org/PathwayBrowser/#/R-MMU-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Mus musculus 18420 R-MMU-71401 https://reactome.org/PathwayBrowser/#/R-MMU-71401 OGDH dimer decarboxylates 2-OG IEA Mus musculus 18420 R-MMU-71660 https://reactome.org/PathwayBrowser/#/R-MMU-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Mus musculus 18420 R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 18420 R-MMU-71732 https://reactome.org/PathwayBrowser/#/R-MMU-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Mus musculus 18420 R-MMU-71775 https://reactome.org/PathwayBrowser/#/R-MMU-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Mus musculus 18420 R-MMU-71850 https://reactome.org/PathwayBrowser/#/R-MMU-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Mus musculus 18420 R-MMU-73598 https://reactome.org/PathwayBrowser/#/R-MMU-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Mus musculus 18420 R-MMU-73605 https://reactome.org/PathwayBrowser/#/R-MMU-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Mus musculus 18420 R-MMU-74215 https://reactome.org/PathwayBrowser/#/R-MMU-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Mus musculus 18420 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 18420 R-MMU-74948 https://reactome.org/PathwayBrowser/#/R-MMU-74948 PP2A dephosphorylates p-RHO to RHO IEA Mus musculus 18420 R-MMU-8850846 https://reactome.org/PathwayBrowser/#/R-MMU-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Mus musculus 18420 R-MMU-8850854 https://reactome.org/PathwayBrowser/#/R-MMU-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Mus musculus 18420 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 18420 R-MMU-8851110 https://reactome.org/PathwayBrowser/#/R-MMU-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Mus musculus 18420 R-MMU-8851129 https://reactome.org/PathwayBrowser/#/R-MMU-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Mus musculus 18420 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 18420 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 18420 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 18420 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 18420 R-MMU-8939959 https://reactome.org/PathwayBrowser/#/R-MMU-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Mus musculus 18420 R-MMU-8953499 https://reactome.org/PathwayBrowser/#/R-MMU-8953499 IMPAD1 hydrolyses PAP to AMP IEA Mus musculus 18420 R-MMU-8955760 https://reactome.org/PathwayBrowser/#/R-MMU-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Mus musculus 18420 R-MMU-8982667 https://reactome.org/PathwayBrowser/#/R-MMU-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Mus musculus 18420 R-MMU-9012016 https://reactome.org/PathwayBrowser/#/R-MMU-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Mus musculus 18420 R-MMU-9012036 https://reactome.org/PathwayBrowser/#/R-MMU-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Mus musculus 18420 R-MMU-9012268 https://reactome.org/PathwayBrowser/#/R-MMU-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Mus musculus 18420 R-MMU-9012349 https://reactome.org/PathwayBrowser/#/R-MMU-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Mus musculus 18420 R-MMU-9014741 https://reactome.org/PathwayBrowser/#/R-MMU-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Mus musculus 18420 R-MMU-9014766 https://reactome.org/PathwayBrowser/#/R-MMU-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Mus musculus 18420 R-MMU-9024993 https://reactome.org/PathwayBrowser/#/R-MMU-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Mus musculus 18420 R-MMU-936883 https://reactome.org/PathwayBrowser/#/R-MMU-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Mus musculus 18420 R-MMU-947531 https://reactome.org/PathwayBrowser/#/R-MMU-947531 Molybdenum ion transfer onto molybdopterin IEA Mus musculus 18420 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 18420 R-MMU-9621179 https://reactome.org/PathwayBrowser/#/R-MMU-9621179 Cinaciguat binds sGC:NO IEA Mus musculus 18420 R-MMU-9638125 https://reactome.org/PathwayBrowser/#/R-MMU-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Mus musculus 18420 R-MMU-9638127 https://reactome.org/PathwayBrowser/#/R-MMU-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Mus musculus 18420 R-MMU-9640074 https://reactome.org/PathwayBrowser/#/R-MMU-9640074 Kcnip3 binds Npas4 gene promoter TAS Mus musculus 18420 R-MMU-9640094 https://reactome.org/PathwayBrowser/#/R-MMU-9640094 Ca2+ binds Kcnip3 TAS Mus musculus 18420 R-MMU-965067 https://reactome.org/PathwayBrowser/#/R-MMU-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Mus musculus 18420 R-MMU-9650858 https://reactome.org/PathwayBrowser/#/R-MMU-9650858 Meglitinides bind ABCC8 IEA Mus musculus 18420 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 18420 R-MMU-9657599 https://reactome.org/PathwayBrowser/#/R-MMU-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Mus musculus 18420 R-MMU-9657603 https://reactome.org/PathwayBrowser/#/R-MMU-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Mus musculus 18420 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 18420 R-MMU-9657608 https://reactome.org/PathwayBrowser/#/R-MMU-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Mus musculus 18420 R-MMU-9713712 https://reactome.org/PathwayBrowser/#/R-MMU-9713712 Adcy3:Gnal:GTP converts ATP to cAMP TAS Mus musculus 18420 R-MMU-9717830 https://reactome.org/PathwayBrowser/#/R-MMU-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Mus musculus 18420 R-MMU-9717834 https://reactome.org/PathwayBrowser/#/R-MMU-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Mus musculus 18420 R-MMU-9717841 https://reactome.org/PathwayBrowser/#/R-MMU-9717841 holo-FDPS dimer binds NBPs IEA Mus musculus 18420 R-MMU-9731228 https://reactome.org/PathwayBrowser/#/R-MMU-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Mus musculus 18420 R-MMU-9731590 https://reactome.org/PathwayBrowser/#/R-MMU-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Mus musculus 18420 R-MMU-9731613 https://reactome.org/PathwayBrowser/#/R-MMU-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Mus musculus 18420 R-MMU-9731632 https://reactome.org/PathwayBrowser/#/R-MMU-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Mus musculus 18420 R-MMU-9748951 https://reactome.org/PathwayBrowser/#/R-MMU-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Mus musculus 18420 R-MMU-9754916 https://reactome.org/PathwayBrowser/#/R-MMU-9754916 NT5C2 tetramer phosphorylates RBV IEA Mus musculus 18420 R-MMU-9754974 https://reactome.org/PathwayBrowser/#/R-MMU-9754974 ADK phosphorylates RBV IEA Mus musculus 18420 R-MMU-9755078 https://reactome.org/PathwayBrowser/#/R-MMU-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Mus musculus 18420 R-MMU-9770141 https://reactome.org/PathwayBrowser/#/R-MMU-9770141 Formation of the Spliceosomal C* complex IEA Mus musculus 18420 R-MMU-9770145 https://reactome.org/PathwayBrowser/#/R-MMU-9770145 Formation of the Spliceosomal Bact complex IEA Mus musculus 18420 R-MMU-9770236 https://reactome.org/PathwayBrowser/#/R-MMU-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Mus musculus 18420 R-MMU-977324 https://reactome.org/PathwayBrowser/#/R-MMU-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Mus musculus 18420 R-MMU-9821987 https://reactome.org/PathwayBrowser/#/R-MMU-9821987 Srpk1 phosphorylates Prm2 in Prm2:dsDNA TAS Mus musculus 18420 R-MMU-9821990 https://reactome.org/PathwayBrowser/#/R-MMU-9821990 Srpk1 phosphorylates Prm1 in Prm1:dsDNA TAS Mus musculus 18420 R-MMU-983153 https://reactome.org/PathwayBrowser/#/R-MMU-983153 E1 mediated ubiquitin activation IEA Mus musculus 18420 R-MMU-9853499 https://reactome.org/PathwayBrowser/#/R-MMU-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 18420 R-MMU-9853512 https://reactome.org/PathwayBrowser/#/R-MMU-9853512 DLST transfers succinyl to CoA IEA Mus musculus 18420 R-MMU-9861616 https://reactome.org/PathwayBrowser/#/R-MMU-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 18420 R-MMU-9861631 https://reactome.org/PathwayBrowser/#/R-MMU-9861631 ME1 tetramerizes IEA Mus musculus 18420 R-MMU-9861642 https://reactome.org/PathwayBrowser/#/R-MMU-9861642 NEK1 phosphorylates ME1 IEA Mus musculus 18420 R-MMU-9861660 https://reactome.org/PathwayBrowser/#/R-MMU-9861660 ME1 tetramer decarboxylates OA to PYR IEA Mus musculus 18420 R-MMU-9861667 https://reactome.org/PathwayBrowser/#/R-MMU-9861667 DLAT trimer transfers acetyl to CoA IEA Mus musculus 18420 R-MMU-9861734 https://reactome.org/PathwayBrowser/#/R-MMU-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Mus musculus 18420 R-MTU-868608 https://reactome.org/PathwayBrowser/#/R-MTU-868608 Trehalose-6-phosphate is hydrolyzed to trehalose TAS Mycobacterium tuberculosis 18420 R-MTU-936659 https://reactome.org/PathwayBrowser/#/R-MTU-936659 PAPS is dephosphorylated to APS TAS Mycobacterium tuberculosis 18420 R-MTU-964939 https://reactome.org/PathwayBrowser/#/R-MTU-964939 Phosphorylation of shikimate TAS Mycobacterium tuberculosis 18420 R-NUL-350485 https://reactome.org/PathwayBrowser/#/R-NUL-350485 RhoA:GTP binds to activated Daam1 TAS Homo sapiens 18420 R-NUL-421821 https://reactome.org/PathwayBrowser/#/R-NUL-421821 G alpha (i) inhibits adenylate cyclase TAS Canis familiaris 18420 R-PFA-111215 https://reactome.org/PathwayBrowser/#/R-PFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Plasmodium falciparum 18420 R-PFA-111524 https://reactome.org/PathwayBrowser/#/R-PFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Plasmodium falciparum 18420 R-PFA-1482961 https://reactome.org/PathwayBrowser/#/R-PFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Plasmodium falciparum 18420 R-PFA-1482962 https://reactome.org/PathwayBrowser/#/R-PFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Plasmodium falciparum 18420 R-PFA-1482973 https://reactome.org/PathwayBrowser/#/R-PFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Plasmodium falciparum 18420 R-PFA-1482976 https://reactome.org/PathwayBrowser/#/R-PFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Plasmodium falciparum 18420 R-PFA-1483121 https://reactome.org/PathwayBrowser/#/R-PFA-1483121 PA is converted to CDP-DAG by CDS1 IEA Plasmodium falciparum 18420 R-PFA-1483203 https://reactome.org/PathwayBrowser/#/R-PFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Plasmodium falciparum 18420 R-PFA-1606273 https://reactome.org/PathwayBrowser/#/R-PFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Plasmodium falciparum 18420 R-PFA-174391 https://reactome.org/PathwayBrowser/#/R-PFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Plasmodium falciparum 18420 R-PFA-174394 https://reactome.org/PathwayBrowser/#/R-PFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Plasmodium falciparum 18420 R-PFA-191303 https://reactome.org/PathwayBrowser/#/R-PFA-191303 FDPS dimer transfers IPPP to GPP IEA Plasmodium falciparum 18420 R-PFA-191322 https://reactome.org/PathwayBrowser/#/R-PFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Plasmodium falciparum 18420 R-PFA-196761 https://reactome.org/PathwayBrowser/#/R-PFA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Plasmodium falciparum 18420 R-PFA-196964 https://reactome.org/PathwayBrowser/#/R-PFA-196964 RFK:Mg2+ phosphorylates RIB IEA Plasmodium falciparum 18420 R-PFA-197186 https://reactome.org/PathwayBrowser/#/R-PFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Plasmodium falciparum 18420 R-PFA-2046085 https://reactome.org/PathwayBrowser/#/R-PFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Plasmodium falciparum 18420 R-PFA-2046098 https://reactome.org/PathwayBrowser/#/R-PFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Plasmodium falciparum 18420 R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Plasmodium falciparum 18420 R-PFA-2162253 https://reactome.org/PathwayBrowser/#/R-PFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Plasmodium falciparum 18420 R-PFA-2395818 https://reactome.org/PathwayBrowser/#/R-PFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Plasmodium falciparum 18420 R-PFA-2395849 https://reactome.org/PathwayBrowser/#/R-PFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Plasmodium falciparum 18420 R-PFA-2395872 https://reactome.org/PathwayBrowser/#/R-PFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Plasmodium falciparum 18420 R-PFA-2408551 https://reactome.org/PathwayBrowser/#/R-PFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Plasmodium falciparum 18420 R-PFA-2509827 https://reactome.org/PathwayBrowser/#/R-PFA-2509827 ITPA hydrolyses ITP to IMP IEA Plasmodium falciparum 18420 R-PFA-2509831 https://reactome.org/PathwayBrowser/#/R-PFA-2509831 ITPA hydrolyses XTP to XMP IEA Plasmodium falciparum 18420 R-PFA-2509838 https://reactome.org/PathwayBrowser/#/R-PFA-2509838 ITPA hydrolyses dITP to dIMP IEA Plasmodium falciparum 18420 R-PFA-449937 https://reactome.org/PathwayBrowser/#/R-PFA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Plasmodium falciparum 18420 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 18420 R-PFA-5336466 https://reactome.org/PathwayBrowser/#/R-PFA-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Plasmodium falciparum 18420 R-PFA-5339528 https://reactome.org/PathwayBrowser/#/R-PFA-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Plasmodium falciparum 18420 R-PFA-5339538 https://reactome.org/PathwayBrowser/#/R-PFA-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Plasmodium falciparum 18420 R-PFA-5655892 https://reactome.org/PathwayBrowser/#/R-PFA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Plasmodium falciparum 18420 R-PFA-5655965 https://reactome.org/PathwayBrowser/#/R-PFA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Plasmodium falciparum 18420 R-PFA-5656148 https://reactome.org/PathwayBrowser/#/R-PFA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Plasmodium falciparum 18420 R-PFA-5656158 https://reactome.org/PathwayBrowser/#/R-PFA-5656158 POLZ elongates POLI-incorporated dNMP IEA Plasmodium falciparum 18420 R-PFA-5694018 https://reactome.org/PathwayBrowser/#/R-PFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Plasmodium falciparum 18420 R-PFA-6787329 https://reactome.org/PathwayBrowser/#/R-PFA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Plasmodium falciparum 18420 R-PFA-70486 https://reactome.org/PathwayBrowser/#/R-PFA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Plasmodium falciparum 18420 R-PFA-70494 https://reactome.org/PathwayBrowser/#/R-PFA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Plasmodium falciparum 18420 R-PFA-70997 https://reactome.org/PathwayBrowser/#/R-PFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Plasmodium falciparum 18420 R-PFA-71401 https://reactome.org/PathwayBrowser/#/R-PFA-71401 OGDH dimer decarboxylates 2-OG IEA Plasmodium falciparum 18420 R-PFA-71660 https://reactome.org/PathwayBrowser/#/R-PFA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Plasmodium falciparum 18420 R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 18420 R-PFA-71732 https://reactome.org/PathwayBrowser/#/R-PFA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Plasmodium falciparum 18420 R-PFA-71775 https://reactome.org/PathwayBrowser/#/R-PFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Plasmodium falciparum 18420 R-PFA-71850 https://reactome.org/PathwayBrowser/#/R-PFA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Plasmodium falciparum 18420 R-PFA-73605 https://reactome.org/PathwayBrowser/#/R-PFA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Plasmodium falciparum 18420 R-PFA-74215 https://reactome.org/PathwayBrowser/#/R-PFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Plasmodium falciparum 18420 R-PFA-8850846 https://reactome.org/PathwayBrowser/#/R-PFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 18420 R-PFA-8850854 https://reactome.org/PathwayBrowser/#/R-PFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 18420 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 18420 R-PFA-8851110 https://reactome.org/PathwayBrowser/#/R-PFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 18420 R-PFA-8851129 https://reactome.org/PathwayBrowser/#/R-PFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 18420 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 18420 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 18420 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 18420 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 18420 R-PFA-8955760 https://reactome.org/PathwayBrowser/#/R-PFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Plasmodium falciparum 18420 R-PFA-8982667 https://reactome.org/PathwayBrowser/#/R-PFA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Plasmodium falciparum 18420 R-PFA-9024993 https://reactome.org/PathwayBrowser/#/R-PFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Plasmodium falciparum 18420 R-PFA-936883 https://reactome.org/PathwayBrowser/#/R-PFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Plasmodium falciparum 18420 R-PFA-9717841 https://reactome.org/PathwayBrowser/#/R-PFA-9717841 holo-FDPS dimer binds NBPs IEA Plasmodium falciparum 18420 R-PFA-9731228 https://reactome.org/PathwayBrowser/#/R-PFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Plasmodium falciparum 18420 R-PFA-9731590 https://reactome.org/PathwayBrowser/#/R-PFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Plasmodium falciparum 18420 R-PFA-9731613 https://reactome.org/PathwayBrowser/#/R-PFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Plasmodium falciparum 18420 R-PFA-9731632 https://reactome.org/PathwayBrowser/#/R-PFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Plasmodium falciparum 18420 R-PFA-9748951 https://reactome.org/PathwayBrowser/#/R-PFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Plasmodium falciparum 18420 R-PFA-983153 https://reactome.org/PathwayBrowser/#/R-PFA-983153 E1 mediated ubiquitin activation IEA Plasmodium falciparum 18420 R-PFA-9853499 https://reactome.org/PathwayBrowser/#/R-PFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Plasmodium falciparum 18420 R-PFA-9853512 https://reactome.org/PathwayBrowser/#/R-PFA-9853512 DLST transfers succinyl to CoA IEA Plasmodium falciparum 18420 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 18420 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 18420 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 18420 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 18420 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 18420 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 18420 R-RNO-109624 https://reactome.org/PathwayBrowser/#/R-RNO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Rattus norvegicus 18420 R-RNO-109671 https://reactome.org/PathwayBrowser/#/R-RNO-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Rattus norvegicus 18420 R-RNO-111215 https://reactome.org/PathwayBrowser/#/R-RNO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Rattus norvegicus 18420 R-RNO-111524 https://reactome.org/PathwayBrowser/#/R-RNO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Rattus norvegicus 18420 R-RNO-111930 https://reactome.org/PathwayBrowser/#/R-RNO-111930 Adenylate cyclase produces cAMP IEA Rattus norvegicus 18420 R-RNO-1237129 https://reactome.org/PathwayBrowser/#/R-RNO-1237129 Acireductone is created IEA Rattus norvegicus 18420 R-RNO-1482961 https://reactome.org/PathwayBrowser/#/R-RNO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Rattus norvegicus 18420 R-RNO-1482962 https://reactome.org/PathwayBrowser/#/R-RNO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Rattus norvegicus 18420 R-RNO-1482973 https://reactome.org/PathwayBrowser/#/R-RNO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Rattus norvegicus 18420 R-RNO-1482976 https://reactome.org/PathwayBrowser/#/R-RNO-1482976 CDP-DAG is converted to PI by CDIPT IEA Rattus norvegicus 18420 R-RNO-1483096 https://reactome.org/PathwayBrowser/#/R-RNO-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Rattus norvegicus 18420 R-RNO-1483121 https://reactome.org/PathwayBrowser/#/R-RNO-1483121 PA is converted to CDP-DAG by CDS1 IEA Rattus norvegicus 18420 R-RNO-1483159 https://reactome.org/PathwayBrowser/#/R-RNO-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Rattus norvegicus 18420 R-RNO-1483203 https://reactome.org/PathwayBrowser/#/R-RNO-1483203 PA is dephosphorylated to DAG by LPIN IEA Rattus norvegicus 18420 R-RNO-1606273 https://reactome.org/PathwayBrowser/#/R-RNO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Rattus norvegicus 18420 R-RNO-1606288 https://reactome.org/PathwayBrowser/#/R-RNO-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Rattus norvegicus 18420 R-RNO-163741 https://reactome.org/PathwayBrowser/#/R-RNO-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Rattus norvegicus 18420 R-RNO-163751 https://reactome.org/PathwayBrowser/#/R-RNO-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Rattus norvegicus 18420 R-RNO-1675928 https://reactome.org/PathwayBrowser/#/R-RNO-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Rattus norvegicus 18420 R-RNO-1675939 https://reactome.org/PathwayBrowser/#/R-RNO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Rattus norvegicus 18420 R-RNO-1675961 https://reactome.org/PathwayBrowser/#/R-RNO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Rattus norvegicus 18420 R-RNO-1676024 https://reactome.org/PathwayBrowser/#/R-RNO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Rattus norvegicus 18420 R-RNO-1676109 https://reactome.org/PathwayBrowser/#/R-RNO-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Rattus norvegicus 18420 R-RNO-1676206 https://reactome.org/PathwayBrowser/#/R-RNO-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Rattus norvegicus 18420 R-RNO-170666 https://reactome.org/PathwayBrowser/#/R-RNO-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Rattus norvegicus 18420 R-RNO-170671 https://reactome.org/PathwayBrowser/#/R-RNO-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Rattus norvegicus 18420 R-RNO-170672 https://reactome.org/PathwayBrowser/#/R-RNO-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Rattus norvegicus 18420 R-RNO-170674 https://reactome.org/PathwayBrowser/#/R-RNO-170674 Dissociation of the Gi alpha:G olf complex IEA Rattus norvegicus 18420 R-RNO-170676 https://reactome.org/PathwayBrowser/#/R-RNO-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Rattus norvegicus 18420 R-RNO-170677 https://reactome.org/PathwayBrowser/#/R-RNO-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Rattus norvegicus 18420 R-RNO-170685 https://reactome.org/PathwayBrowser/#/R-RNO-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Rattus norvegicus 18420 R-RNO-170686 https://reactome.org/PathwayBrowser/#/R-RNO-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Rattus norvegicus 18420 R-RNO-174391 https://reactome.org/PathwayBrowser/#/R-RNO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Rattus norvegicus 18420 R-RNO-174394 https://reactome.org/PathwayBrowser/#/R-RNO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Rattus norvegicus 18420 R-RNO-1855154 https://reactome.org/PathwayBrowser/#/R-RNO-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855159 https://reactome.org/PathwayBrowser/#/R-RNO-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855162 https://reactome.org/PathwayBrowser/#/R-RNO-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855165 https://reactome.org/PathwayBrowser/#/R-RNO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855166 https://reactome.org/PathwayBrowser/#/R-RNO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855169 https://reactome.org/PathwayBrowser/#/R-RNO-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855171 https://reactome.org/PathwayBrowser/#/R-RNO-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855172 https://reactome.org/PathwayBrowser/#/R-RNO-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855197 https://reactome.org/PathwayBrowser/#/R-RNO-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855198 https://reactome.org/PathwayBrowser/#/R-RNO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855205 https://reactome.org/PathwayBrowser/#/R-RNO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855208 https://reactome.org/PathwayBrowser/#/R-RNO-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855210 https://reactome.org/PathwayBrowser/#/R-RNO-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855211 https://reactome.org/PathwayBrowser/#/R-RNO-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855218 https://reactome.org/PathwayBrowser/#/R-RNO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855219 https://reactome.org/PathwayBrowser/#/R-RNO-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 18420 R-RNO-1855232 https://reactome.org/PathwayBrowser/#/R-RNO-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Rattus norvegicus 18420 R-RNO-187682 https://reactome.org/PathwayBrowser/#/R-RNO-187682 Binding and activation of MAP kinase TAS Rattus norvegicus 18420 R-RNO-187688 https://reactome.org/PathwayBrowser/#/R-RNO-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Rattus norvegicus 18420 R-RNO-191303 https://reactome.org/PathwayBrowser/#/R-RNO-191303 FDPS dimer transfers IPPP to GPP IEA Rattus norvegicus 18420 R-RNO-191322 https://reactome.org/PathwayBrowser/#/R-RNO-191322 FDPS dimer transfers IPPP to DMAPP IEA Rattus norvegicus 18420 R-RNO-191382 https://reactome.org/PathwayBrowser/#/R-RNO-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Rattus norvegicus 18420 R-RNO-191402 https://reactome.org/PathwayBrowser/#/R-RNO-191402 Reduction of presqualene diphosphate to form squalene IEA Rattus norvegicus 18420 R-RNO-191405 https://reactome.org/PathwayBrowser/#/R-RNO-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Rattus norvegicus 18420 R-RNO-194339 https://reactome.org/PathwayBrowser/#/R-RNO-194339 Sphingomyelinase is activated by the NGF:p75NTR complex TAS Rattus norvegicus 18420 R-RNO-196761 https://reactome.org/PathwayBrowser/#/R-RNO-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Rattus norvegicus 18420 R-RNO-196964 https://reactome.org/PathwayBrowser/#/R-RNO-196964 RFK:Mg2+ phosphorylates RIB IEA Rattus norvegicus 18420 R-RNO-197186 https://reactome.org/PathwayBrowser/#/R-RNO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Rattus norvegicus 18420 R-RNO-197235 https://reactome.org/PathwayBrowser/#/R-RNO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 18420 R-RNO-200474 https://reactome.org/PathwayBrowser/#/R-RNO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 18420 R-RNO-2023971 https://reactome.org/PathwayBrowser/#/R-RNO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 18420 R-RNO-2023973 https://reactome.org/PathwayBrowser/#/R-RNO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 18420 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 18420 R-RNO-204169 https://reactome.org/PathwayBrowser/#/R-RNO-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Rattus norvegicus 18420 R-RNO-2046085 https://reactome.org/PathwayBrowser/#/R-RNO-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Rattus norvegicus 18420 R-RNO-2046098 https://reactome.org/PathwayBrowser/#/R-RNO-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Rattus norvegicus 18420 R-RNO-209562 https://reactome.org/PathwayBrowser/#/R-RNO-209562 Production of ceramide which can activate JNK and other targets TAS Rattus norvegicus 18420 R-RNO-216043 https://reactome.org/PathwayBrowser/#/R-RNO-216043 Collagen type II binds integrin alpha10beta1 IEA Rattus norvegicus 18420 R-RNO-216045 https://reactome.org/PathwayBrowser/#/R-RNO-216045 Collagen type I binds integrin alpha11beta1 IEA Rattus norvegicus 18420 R-RNO-216069 https://reactome.org/PathwayBrowser/#/R-RNO-216069 Interaction of integrin alphaDbeta2 with fibrin IEA Rattus norvegicus 18420 R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Rattus norvegicus 18420 R-RNO-2162066 https://reactome.org/PathwayBrowser/#/R-RNO-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Rattus norvegicus 18420 R-RNO-2162253 https://reactome.org/PathwayBrowser/#/R-RNO-2162253 PDSS1,2 ligates FPP to IPPP IEA Rattus norvegicus 18420 R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 18420 R-RNO-2393939 https://reactome.org/PathwayBrowser/#/R-RNO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 18420 R-RNO-2393954 https://reactome.org/PathwayBrowser/#/R-RNO-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 18420 R-RNO-2395818 https://reactome.org/PathwayBrowser/#/R-RNO-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Rattus norvegicus 18420 R-RNO-2395849 https://reactome.org/PathwayBrowser/#/R-RNO-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 18420 R-RNO-2395872 https://reactome.org/PathwayBrowser/#/R-RNO-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Rattus norvegicus 18420 R-RNO-2408551 https://reactome.org/PathwayBrowser/#/R-RNO-2408551 SeMet is converted to AdoSeMet by MAT IEA Rattus norvegicus 18420 R-RNO-2509793 https://reactome.org/PathwayBrowser/#/R-RNO-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Rattus norvegicus 18420 R-RNO-2509816 https://reactome.org/PathwayBrowser/#/R-RNO-2509816 NUDT16 hydrolyses IDP to IMP IEA Rattus norvegicus 18420 R-RNO-2509827 https://reactome.org/PathwayBrowser/#/R-RNO-2509827 ITPA hydrolyses ITP to IMP IEA Rattus norvegicus 18420 R-RNO-2509831 https://reactome.org/PathwayBrowser/#/R-RNO-2509831 ITPA hydrolyses XTP to XMP IEA Rattus norvegicus 18420 R-RNO-2509838 https://reactome.org/PathwayBrowser/#/R-RNO-2509838 ITPA hydrolyses dITP to dIMP IEA Rattus norvegicus 18420 R-RNO-265682 https://reactome.org/PathwayBrowser/#/R-RNO-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Rattus norvegicus 18420 R-RNO-3322001 https://reactome.org/PathwayBrowser/#/R-RNO-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Rattus norvegicus 18420 R-RNO-3322003 https://reactome.org/PathwayBrowser/#/R-RNO-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Rattus norvegicus 18420 R-RNO-3322005 https://reactome.org/PathwayBrowser/#/R-RNO-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Rattus norvegicus 18420 R-RNO-3322025 https://reactome.org/PathwayBrowser/#/R-RNO-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Rattus norvegicus 18420 R-RNO-3322041 https://reactome.org/PathwayBrowser/#/R-RNO-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Rattus norvegicus 18420 R-RNO-3322057 https://reactome.org/PathwayBrowser/#/R-RNO-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Rattus norvegicus 18420 R-RNO-354066 https://reactome.org/PathwayBrowser/#/R-RNO-354066 Translocation of PTK2 to Focal complexes IEA Rattus norvegicus 18420 R-RNO-354073 https://reactome.org/PathwayBrowser/#/R-RNO-354073 Autophosphorylation of PTK2 at Y397 IEA Rattus norvegicus 18420 R-RNO-354087 https://reactome.org/PathwayBrowser/#/R-RNO-354087 Recruitment of GRB2 to p-PTK2 IEA Rattus norvegicus 18420 R-RNO-354124 https://reactome.org/PathwayBrowser/#/R-RNO-354124 Phosphorylation of pPTK2 by SRC IEA Rattus norvegicus 18420 R-RNO-354149 https://reactome.org/PathwayBrowser/#/R-RNO-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Rattus norvegicus 18420 R-RNO-354165 https://reactome.org/PathwayBrowser/#/R-RNO-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Rattus norvegicus 18420 R-RNO-372693 https://reactome.org/PathwayBrowser/#/R-RNO-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Rattus norvegicus 18420 R-RNO-372697 https://reactome.org/PathwayBrowser/#/R-RNO-372697 Crk binding to p130cas IEA Rattus norvegicus 18420 R-RNO-372705 https://reactome.org/PathwayBrowser/#/R-RNO-372705 Recruitment of BCAR1 to PTK2 complex IEA Rattus norvegicus 18420 R-RNO-377640 https://reactome.org/PathwayBrowser/#/R-RNO-377640 Autophosphorylation of SRC IEA Rattus norvegicus 18420 R-RNO-377641 https://reactome.org/PathwayBrowser/#/R-RNO-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Rattus norvegicus 18420 R-RNO-377643 https://reactome.org/PathwayBrowser/#/R-RNO-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Rattus norvegicus 18420 R-RNO-377644 https://reactome.org/PathwayBrowser/#/R-RNO-377644 Release of CSK from SRC IEA Rattus norvegicus 18420 R-RNO-3781018 https://reactome.org/PathwayBrowser/#/R-RNO-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Rattus norvegicus 18420 R-RNO-3781023 https://reactome.org/PathwayBrowser/#/R-RNO-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Rattus norvegicus 18420 R-RNO-3781024 https://reactome.org/PathwayBrowser/#/R-RNO-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Rattus norvegicus 18420 R-RNO-3858495 https://reactome.org/PathwayBrowser/#/R-RNO-3858495 DAAM1 recruits GTP-bound RHOA IEA Rattus norvegicus 18420 R-RNO-389611 https://reactome.org/PathwayBrowser/#/R-RNO-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Rattus norvegicus 18420 R-RNO-392064 https://reactome.org/PathwayBrowser/#/R-RNO-392064 G alpha (z) inhibits adenylate cyclase IEA Rattus norvegicus 18420 R-RNO-4084989 https://reactome.org/PathwayBrowser/#/R-RNO-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Rattus norvegicus 18420 R-RNO-426223 https://reactome.org/PathwayBrowser/#/R-RNO-426223 Cation influx mediated by TRPC3/6/7 IEA Rattus norvegicus 18420 R-RNO-427279 https://reactome.org/PathwayBrowser/#/R-RNO-427279 NO binds to Guanylate Cyclase TAS Rattus norvegicus 18420 R-RNO-427288 https://reactome.org/PathwayBrowser/#/R-RNO-427288 Soluble guanylate cyclase converts GTP to cGMP TAS Rattus norvegicus 18420 R-RNO-429415 https://reactome.org/PathwayBrowser/#/R-RNO-429415 SYK binds to integrin alphaIIb beta3 IEA Rattus norvegicus 18420 R-RNO-429441 https://reactome.org/PathwayBrowser/#/R-RNO-429441 SYK activation by SRC IEA Rattus norvegicus 18420 R-RNO-442661 https://reactome.org/PathwayBrowser/#/R-RNO-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol IEA Rattus norvegicus 18420 R-RNO-449937 https://reactome.org/PathwayBrowser/#/R-RNO-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Rattus norvegicus 18420 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 18420 R-RNO-5218804 https://reactome.org/PathwayBrowser/#/R-RNO-5218804 p38 MAPK activation by VEGFR IEA Rattus norvegicus 18420 R-RNO-5218826 https://reactome.org/PathwayBrowser/#/R-RNO-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Rattus norvegicus 18420 R-RNO-5228992 https://reactome.org/PathwayBrowser/#/R-RNO-5228992 ROCK1,ROCK2 are activated IEA Rattus norvegicus 18420 R-RNO-5336453 https://reactome.org/PathwayBrowser/#/R-RNO-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Rattus norvegicus 18420 R-RNO-5336466 https://reactome.org/PathwayBrowser/#/R-RNO-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Rattus norvegicus 18420 R-RNO-5339528 https://reactome.org/PathwayBrowser/#/R-RNO-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Rattus norvegicus 18420 R-RNO-5339538 https://reactome.org/PathwayBrowser/#/R-RNO-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Rattus norvegicus 18420 R-RNO-5603114 https://reactome.org/PathwayBrowser/#/R-RNO-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Rattus norvegicus 18420 R-RNO-5610727 https://reactome.org/PathwayBrowser/#/R-RNO-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Rattus norvegicus 18420 R-RNO-5655835 https://reactome.org/PathwayBrowser/#/R-RNO-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Rattus norvegicus 18420 R-RNO-5655892 https://reactome.org/PathwayBrowser/#/R-RNO-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Rattus norvegicus 18420 R-RNO-5655965 https://reactome.org/PathwayBrowser/#/R-RNO-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Rattus norvegicus 18420 R-RNO-5656105 https://reactome.org/PathwayBrowser/#/R-RNO-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Rattus norvegicus 18420 R-RNO-5656148 https://reactome.org/PathwayBrowser/#/R-RNO-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Rattus norvegicus 18420 R-RNO-5656158 https://reactome.org/PathwayBrowser/#/R-RNO-5656158 POLZ elongates POLI-incorporated dNMP IEA Rattus norvegicus 18420 R-RNO-5672972 https://reactome.org/PathwayBrowser/#/R-RNO-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Rattus norvegicus 18420 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 18420 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 18420 R-RNO-5672980 https://reactome.org/PathwayBrowser/#/R-RNO-5672980 Dissociation of RAS:RAF complex IEA Rattus norvegicus 18420 R-RNO-5694018 https://reactome.org/PathwayBrowser/#/R-RNO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Rattus norvegicus 18420 R-RNO-5696021 https://reactome.org/PathwayBrowser/#/R-RNO-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Rattus norvegicus 18420 R-RNO-5696074 https://reactome.org/PathwayBrowser/#/R-RNO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Rattus norvegicus 18420 R-RNO-6787329 https://reactome.org/PathwayBrowser/#/R-RNO-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Rattus norvegicus 18420 R-RNO-6788295 https://reactome.org/PathwayBrowser/#/R-RNO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Rattus norvegicus 18420 R-RNO-6788597 https://reactome.org/PathwayBrowser/#/R-RNO-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Rattus norvegicus 18420 R-RNO-6788912 https://reactome.org/PathwayBrowser/#/R-RNO-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Rattus norvegicus 18420 R-RNO-70349 https://reactome.org/PathwayBrowser/#/R-RNO-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 18420 R-RNO-70479 https://reactome.org/PathwayBrowser/#/R-RNO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Rattus norvegicus 18420 R-RNO-70486 https://reactome.org/PathwayBrowser/#/R-RNO-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Rattus norvegicus 18420 R-RNO-70494 https://reactome.org/PathwayBrowser/#/R-RNO-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Rattus norvegicus 18420 R-RNO-70997 https://reactome.org/PathwayBrowser/#/R-RNO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Rattus norvegicus 18420 R-RNO-71037 https://reactome.org/PathwayBrowser/#/R-RNO-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 18420 R-RNO-71181 https://reactome.org/PathwayBrowser/#/R-RNO-71181 FAH cleaves 4FAA IEA Rattus norvegicus 18420 R-RNO-71324 https://reactome.org/PathwayBrowser/#/R-RNO-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 18420 R-RNO-71335 https://reactome.org/PathwayBrowser/#/R-RNO-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Rattus norvegicus 18420 R-RNO-71401 https://reactome.org/PathwayBrowser/#/R-RNO-71401 OGDH dimer decarboxylates 2-OG IEA Rattus norvegicus 18420 R-RNO-71660 https://reactome.org/PathwayBrowser/#/R-RNO-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Rattus norvegicus 18420 R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 18420 R-RNO-71732 https://reactome.org/PathwayBrowser/#/R-RNO-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Rattus norvegicus 18420 R-RNO-71775 https://reactome.org/PathwayBrowser/#/R-RNO-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Rattus norvegicus 18420 R-RNO-71850 https://reactome.org/PathwayBrowser/#/R-RNO-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Rattus norvegicus 18420 R-RNO-73598 https://reactome.org/PathwayBrowser/#/R-RNO-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Rattus norvegicus 18420 R-RNO-73605 https://reactome.org/PathwayBrowser/#/R-RNO-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Rattus norvegicus 18420 R-RNO-74215 https://reactome.org/PathwayBrowser/#/R-RNO-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Rattus norvegicus 18420 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 18420 R-RNO-74948 https://reactome.org/PathwayBrowser/#/R-RNO-74948 PP2A dephosphorylates p-RHO to RHO IEA Rattus norvegicus 18420 R-RNO-8850846 https://reactome.org/PathwayBrowser/#/R-RNO-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 18420 R-RNO-8850854 https://reactome.org/PathwayBrowser/#/R-RNO-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 18420 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 18420 R-RNO-8851110 https://reactome.org/PathwayBrowser/#/R-RNO-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 18420 R-RNO-8851129 https://reactome.org/PathwayBrowser/#/R-RNO-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 18420 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 18420 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 18420 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 18420 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 18420 R-RNO-8939959 https://reactome.org/PathwayBrowser/#/R-RNO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Rattus norvegicus 18420 R-RNO-8953499 https://reactome.org/PathwayBrowser/#/R-RNO-8953499 IMPAD1 hydrolyses PAP to AMP IEA Rattus norvegicus 18420 R-RNO-8955760 https://reactome.org/PathwayBrowser/#/R-RNO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Rattus norvegicus 18420 R-RNO-8955775 https://reactome.org/PathwayBrowser/#/R-RNO-8955775 Pgp:Mg2+ dimer hydrolyses 3PG to glycerol TAS Rattus norvegicus 18420 R-RNO-8982667 https://reactome.org/PathwayBrowser/#/R-RNO-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Rattus norvegicus 18420 R-RNO-9012016 https://reactome.org/PathwayBrowser/#/R-RNO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Rattus norvegicus 18420 R-RNO-9012036 https://reactome.org/PathwayBrowser/#/R-RNO-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 18420 R-RNO-9012268 https://reactome.org/PathwayBrowser/#/R-RNO-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 18420 R-RNO-9012349 https://reactome.org/PathwayBrowser/#/R-RNO-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 18420 R-RNO-9014741 https://reactome.org/PathwayBrowser/#/R-RNO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Rattus norvegicus 18420 R-RNO-9014766 https://reactome.org/PathwayBrowser/#/R-RNO-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Rattus norvegicus 18420 R-RNO-9024993 https://reactome.org/PathwayBrowser/#/R-RNO-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Rattus norvegicus 18420 R-RNO-936883 https://reactome.org/PathwayBrowser/#/R-RNO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Rattus norvegicus 18420 R-RNO-947531 https://reactome.org/PathwayBrowser/#/R-RNO-947531 Molybdenum ion transfer onto molybdopterin IEA Rattus norvegicus 18420 R-RNO-9614228 https://reactome.org/PathwayBrowser/#/R-RNO-9614228 Mg2+ binds Grin1:Grin2 NMDA receptors TAS Rattus norvegicus 18420 R-RNO-9614351 https://reactome.org/PathwayBrowser/#/R-RNO-9614351 Unblocking of Grin1:Grin2 NMDA receptors TAS Rattus norvegicus 18420 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 18420 R-RNO-9621179 https://reactome.org/PathwayBrowser/#/R-RNO-9621179 Cinaciguat binds sGC:NO IEA Rattus norvegicus 18420 R-RNO-9638125 https://reactome.org/PathwayBrowser/#/R-RNO-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Rattus norvegicus 18420 R-RNO-9638127 https://reactome.org/PathwayBrowser/#/R-RNO-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Rattus norvegicus 18420 R-RNO-965067 https://reactome.org/PathwayBrowser/#/R-RNO-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Rattus norvegicus 18420 R-RNO-9650858 https://reactome.org/PathwayBrowser/#/R-RNO-9650858 Meglitinides bind ABCC8 IEA Rattus norvegicus 18420 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 18420 R-RNO-9657599 https://reactome.org/PathwayBrowser/#/R-RNO-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Rattus norvegicus 18420 R-RNO-9657603 https://reactome.org/PathwayBrowser/#/R-RNO-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Rattus norvegicus 18420 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 18420 R-RNO-9657608 https://reactome.org/PathwayBrowser/#/R-RNO-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Rattus norvegicus 18420 R-RNO-9713735 https://reactome.org/PathwayBrowser/#/R-RNO-9713735 Adcy3:Gnal:GTP converts ATP to cAMP TAS Rattus norvegicus 18420 R-RNO-9717830 https://reactome.org/PathwayBrowser/#/R-RNO-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Rattus norvegicus 18420 R-RNO-9717834 https://reactome.org/PathwayBrowser/#/R-RNO-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Rattus norvegicus 18420 R-RNO-9717841 https://reactome.org/PathwayBrowser/#/R-RNO-9717841 holo-FDPS dimer binds NBPs IEA Rattus norvegicus 18420 R-RNO-9731228 https://reactome.org/PathwayBrowser/#/R-RNO-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Rattus norvegicus 18420 R-RNO-9731590 https://reactome.org/PathwayBrowser/#/R-RNO-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Rattus norvegicus 18420 R-RNO-9731613 https://reactome.org/PathwayBrowser/#/R-RNO-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Rattus norvegicus 18420 R-RNO-9731632 https://reactome.org/PathwayBrowser/#/R-RNO-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Rattus norvegicus 18420 R-RNO-9748951 https://reactome.org/PathwayBrowser/#/R-RNO-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Rattus norvegicus 18420 R-RNO-9754916 https://reactome.org/PathwayBrowser/#/R-RNO-9754916 NT5C2 tetramer phosphorylates RBV IEA Rattus norvegicus 18420 R-RNO-9754974 https://reactome.org/PathwayBrowser/#/R-RNO-9754974 ADK phosphorylates RBV IEA Rattus norvegicus 18420 R-RNO-9755078 https://reactome.org/PathwayBrowser/#/R-RNO-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Rattus norvegicus 18420 R-RNO-9770141 https://reactome.org/PathwayBrowser/#/R-RNO-9770141 Formation of the Spliceosomal C* complex IEA Rattus norvegicus 18420 R-RNO-9770236 https://reactome.org/PathwayBrowser/#/R-RNO-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Rattus norvegicus 18420 R-RNO-977324 https://reactome.org/PathwayBrowser/#/R-RNO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Rattus norvegicus 18420 R-RNO-983153 https://reactome.org/PathwayBrowser/#/R-RNO-983153 E1 mediated ubiquitin activation IEA Rattus norvegicus 18420 R-RNO-9853499 https://reactome.org/PathwayBrowser/#/R-RNO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 18420 R-RNO-9853512 https://reactome.org/PathwayBrowser/#/R-RNO-9853512 DLST transfers succinyl to CoA IEA Rattus norvegicus 18420 R-RNO-9861616 https://reactome.org/PathwayBrowser/#/R-RNO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 18420 R-RNO-9861631 https://reactome.org/PathwayBrowser/#/R-RNO-9861631 ME1 tetramerizes IEA Rattus norvegicus 18420 R-RNO-9861642 https://reactome.org/PathwayBrowser/#/R-RNO-9861642 NEK1 phosphorylates ME1 IEA Rattus norvegicus 18420 R-RNO-9861660 https://reactome.org/PathwayBrowser/#/R-RNO-9861660 ME1 tetramer decarboxylates OA to PYR IEA Rattus norvegicus 18420 R-RNO-9861667 https://reactome.org/PathwayBrowser/#/R-RNO-9861667 DLAT trimer transfers acetyl to CoA IEA Rattus norvegicus 18420 R-RNO-9861734 https://reactome.org/PathwayBrowser/#/R-RNO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Rattus norvegicus 18420 R-SCE-109624 https://reactome.org/PathwayBrowser/#/R-SCE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Saccharomyces cerevisiae 18420 R-SCE-111215 https://reactome.org/PathwayBrowser/#/R-SCE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Saccharomyces cerevisiae 18420 R-SCE-111524 https://reactome.org/PathwayBrowser/#/R-SCE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Saccharomyces cerevisiae 18420 R-SCE-1237129 https://reactome.org/PathwayBrowser/#/R-SCE-1237129 Acireductone is created IEA Saccharomyces cerevisiae 18420 R-SCE-1482961 https://reactome.org/PathwayBrowser/#/R-SCE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Saccharomyces cerevisiae 18420 R-SCE-1482962 https://reactome.org/PathwayBrowser/#/R-SCE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Saccharomyces cerevisiae 18420 R-SCE-1482973 https://reactome.org/PathwayBrowser/#/R-SCE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Saccharomyces cerevisiae 18420 R-SCE-1482976 https://reactome.org/PathwayBrowser/#/R-SCE-1482976 CDP-DAG is converted to PI by CDIPT IEA Saccharomyces cerevisiae 18420 R-SCE-1483121 https://reactome.org/PathwayBrowser/#/R-SCE-1483121 PA is converted to CDP-DAG by CDS1 IEA Saccharomyces cerevisiae 18420 R-SCE-1483203 https://reactome.org/PathwayBrowser/#/R-SCE-1483203 PA is dephosphorylated to DAG by LPIN IEA Saccharomyces cerevisiae 18420 R-SCE-1606273 https://reactome.org/PathwayBrowser/#/R-SCE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Saccharomyces cerevisiae 18420 R-SCE-174391 https://reactome.org/PathwayBrowser/#/R-SCE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Saccharomyces cerevisiae 18420 R-SCE-174394 https://reactome.org/PathwayBrowser/#/R-SCE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Saccharomyces cerevisiae 18420 R-SCE-1855154 https://reactome.org/PathwayBrowser/#/R-SCE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 18420 R-SCE-1855165 https://reactome.org/PathwayBrowser/#/R-SCE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 18420 R-SCE-1855166 https://reactome.org/PathwayBrowser/#/R-SCE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Saccharomyces cerevisiae 18420 R-SCE-1855198 https://reactome.org/PathwayBrowser/#/R-SCE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 18420 R-SCE-1855205 https://reactome.org/PathwayBrowser/#/R-SCE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Saccharomyces cerevisiae 18420 R-SCE-1855210 https://reactome.org/PathwayBrowser/#/R-SCE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 18420 R-SCE-1855211 https://reactome.org/PathwayBrowser/#/R-SCE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 18420 R-SCE-191303 https://reactome.org/PathwayBrowser/#/R-SCE-191303 FDPS dimer transfers IPPP to GPP IEA Saccharomyces cerevisiae 18420 R-SCE-191322 https://reactome.org/PathwayBrowser/#/R-SCE-191322 FDPS dimer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 18420 R-SCE-191382 https://reactome.org/PathwayBrowser/#/R-SCE-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Saccharomyces cerevisiae 18420 R-SCE-191402 https://reactome.org/PathwayBrowser/#/R-SCE-191402 Reduction of presqualene diphosphate to form squalene IEA Saccharomyces cerevisiae 18420 R-SCE-191405 https://reactome.org/PathwayBrowser/#/R-SCE-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Saccharomyces cerevisiae 18420 R-SCE-196761 https://reactome.org/PathwayBrowser/#/R-SCE-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Saccharomyces cerevisiae 18420 R-SCE-196964 https://reactome.org/PathwayBrowser/#/R-SCE-196964 RFK:Mg2+ phosphorylates RIB IEA Saccharomyces cerevisiae 18420 R-SCE-197186 https://reactome.org/PathwayBrowser/#/R-SCE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Saccharomyces cerevisiae 18420 R-SCE-197235 https://reactome.org/PathwayBrowser/#/R-SCE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 18420 R-SCE-200474 https://reactome.org/PathwayBrowser/#/R-SCE-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 18420 R-SCE-2023971 https://reactome.org/PathwayBrowser/#/R-SCE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 18420 R-SCE-2023973 https://reactome.org/PathwayBrowser/#/R-SCE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 18420 R-SCE-2162253 https://reactome.org/PathwayBrowser/#/R-SCE-2162253 PDSS1,2 ligates FPP to IPPP IEA Saccharomyces cerevisiae 18420 R-SCE-2393939 https://reactome.org/PathwayBrowser/#/R-SCE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Saccharomyces cerevisiae 18420 R-SCE-2408551 https://reactome.org/PathwayBrowser/#/R-SCE-2408551 SeMet is converted to AdoSeMet by MAT IEA Saccharomyces cerevisiae 18420 R-SCE-2509827 https://reactome.org/PathwayBrowser/#/R-SCE-2509827 ITPA hydrolyses ITP to IMP IEA Saccharomyces cerevisiae 18420 R-SCE-2509831 https://reactome.org/PathwayBrowser/#/R-SCE-2509831 ITPA hydrolyses XTP to XMP IEA Saccharomyces cerevisiae 18420 R-SCE-2509838 https://reactome.org/PathwayBrowser/#/R-SCE-2509838 ITPA hydrolyses dITP to dIMP IEA Saccharomyces cerevisiae 18420 R-SCE-3322001 https://reactome.org/PathwayBrowser/#/R-SCE-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Saccharomyces cerevisiae 18420 R-SCE-3322003 https://reactome.org/PathwayBrowser/#/R-SCE-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Saccharomyces cerevisiae 18420 R-SCE-3322005 https://reactome.org/PathwayBrowser/#/R-SCE-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Saccharomyces cerevisiae 18420 R-SCE-3322009 https://reactome.org/PathwayBrowser/#/R-SCE-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Saccharomyces cerevisiae 18420 R-SCE-3322014 https://reactome.org/PathwayBrowser/#/R-SCE-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Saccharomyces cerevisiae 18420 R-SCE-3322016 https://reactome.org/PathwayBrowser/#/R-SCE-3322016 GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a IEA Saccharomyces cerevisiae 18420 R-SCE-3322019 https://reactome.org/PathwayBrowser/#/R-SCE-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Saccharomyces cerevisiae 18420 R-SCE-3322025 https://reactome.org/PathwayBrowser/#/R-SCE-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Saccharomyces cerevisiae 18420 R-SCE-3322041 https://reactome.org/PathwayBrowser/#/R-SCE-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Saccharomyces cerevisiae 18420 R-SCE-3322057 https://reactome.org/PathwayBrowser/#/R-SCE-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Saccharomyces cerevisiae 18420 R-SCE-3780994 https://reactome.org/PathwayBrowser/#/R-SCE-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Saccharomyces cerevisiae 18420 R-SCE-3780997 https://reactome.org/PathwayBrowser/#/R-SCE-3780997 PPP1R3C binds to glycogen:GYG2:GYS2 IEA Saccharomyces cerevisiae 18420 R-SCE-3781011 https://reactome.org/PathwayBrowser/#/R-SCE-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Saccharomyces cerevisiae 18420 R-SCE-3781018 https://reactome.org/PathwayBrowser/#/R-SCE-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Saccharomyces cerevisiae 18420 R-SCE-3781023 https://reactome.org/PathwayBrowser/#/R-SCE-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Saccharomyces cerevisiae 18420 R-SCE-3781024 https://reactome.org/PathwayBrowser/#/R-SCE-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Saccharomyces cerevisiae 18420 R-SCE-389611 https://reactome.org/PathwayBrowser/#/R-SCE-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Saccharomyces cerevisiae 18420 R-SCE-449937 https://reactome.org/PathwayBrowser/#/R-SCE-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Saccharomyces cerevisiae 18420 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 18420 R-SCE-5336466 https://reactome.org/PathwayBrowser/#/R-SCE-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Saccharomyces cerevisiae 18420 R-SCE-5339528 https://reactome.org/PathwayBrowser/#/R-SCE-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 18420 R-SCE-5339538 https://reactome.org/PathwayBrowser/#/R-SCE-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 18420 R-SCE-5655892 https://reactome.org/PathwayBrowser/#/R-SCE-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Saccharomyces cerevisiae 18420 R-SCE-5655965 https://reactome.org/PathwayBrowser/#/R-SCE-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Saccharomyces cerevisiae 18420 R-SCE-5656148 https://reactome.org/PathwayBrowser/#/R-SCE-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Saccharomyces cerevisiae 18420 R-SCE-5656158 https://reactome.org/PathwayBrowser/#/R-SCE-5656158 POLZ elongates POLI-incorporated dNMP IEA Saccharomyces cerevisiae 18420 R-SCE-5694018 https://reactome.org/PathwayBrowser/#/R-SCE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Saccharomyces cerevisiae 18420 R-SCE-5696074 https://reactome.org/PathwayBrowser/#/R-SCE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Saccharomyces cerevisiae 18420 R-SCE-6787329 https://reactome.org/PathwayBrowser/#/R-SCE-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Saccharomyces cerevisiae 18420 R-SCE-6788295 https://reactome.org/PathwayBrowser/#/R-SCE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Saccharomyces cerevisiae 18420 R-SCE-70349 https://reactome.org/PathwayBrowser/#/R-SCE-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Saccharomyces cerevisiae 18420 R-SCE-70479 https://reactome.org/PathwayBrowser/#/R-SCE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Saccharomyces cerevisiae 18420 R-SCE-70486 https://reactome.org/PathwayBrowser/#/R-SCE-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Saccharomyces cerevisiae 18420 R-SCE-70494 https://reactome.org/PathwayBrowser/#/R-SCE-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Saccharomyces cerevisiae 18420 R-SCE-70997 https://reactome.org/PathwayBrowser/#/R-SCE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Saccharomyces cerevisiae 18420 R-SCE-71401 https://reactome.org/PathwayBrowser/#/R-SCE-71401 OGDH dimer decarboxylates 2-OG IEA Saccharomyces cerevisiae 18420 R-SCE-71660 https://reactome.org/PathwayBrowser/#/R-SCE-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Saccharomyces cerevisiae 18420 R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 18420 R-SCE-71732 https://reactome.org/PathwayBrowser/#/R-SCE-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Saccharomyces cerevisiae 18420 R-SCE-71850 https://reactome.org/PathwayBrowser/#/R-SCE-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Saccharomyces cerevisiae 18420 R-SCE-73605 https://reactome.org/PathwayBrowser/#/R-SCE-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Saccharomyces cerevisiae 18420 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 18420 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 18420 R-SCE-8939959 https://reactome.org/PathwayBrowser/#/R-SCE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Saccharomyces cerevisiae 18420 R-SCE-8955760 https://reactome.org/PathwayBrowser/#/R-SCE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Saccharomyces cerevisiae 18420 R-SCE-8982667 https://reactome.org/PathwayBrowser/#/R-SCE-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Saccharomyces cerevisiae 18420 R-SCE-9012016 https://reactome.org/PathwayBrowser/#/R-SCE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Saccharomyces cerevisiae 18420 R-SCE-9014741 https://reactome.org/PathwayBrowser/#/R-SCE-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Saccharomyces cerevisiae 18420 R-SCE-9014766 https://reactome.org/PathwayBrowser/#/R-SCE-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Saccharomyces cerevisiae 18420 R-SCE-936883 https://reactome.org/PathwayBrowser/#/R-SCE-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Saccharomyces cerevisiae 18420 R-SCE-9638125 https://reactome.org/PathwayBrowser/#/R-SCE-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Saccharomyces cerevisiae 18420 R-SCE-9638127 https://reactome.org/PathwayBrowser/#/R-SCE-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Saccharomyces cerevisiae 18420 R-SCE-9717830 https://reactome.org/PathwayBrowser/#/R-SCE-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Saccharomyces cerevisiae 18420 R-SCE-9717834 https://reactome.org/PathwayBrowser/#/R-SCE-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 18420 R-SCE-9717841 https://reactome.org/PathwayBrowser/#/R-SCE-9717841 holo-FDPS dimer binds NBPs IEA Saccharomyces cerevisiae 18420 R-SCE-9754974 https://reactome.org/PathwayBrowser/#/R-SCE-9754974 ADK phosphorylates RBV IEA Saccharomyces cerevisiae 18420 R-SCE-977324 https://reactome.org/PathwayBrowser/#/R-SCE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Saccharomyces cerevisiae 18420 R-SCE-983153 https://reactome.org/PathwayBrowser/#/R-SCE-983153 E1 mediated ubiquitin activation IEA Saccharomyces cerevisiae 18420 R-SCE-9853499 https://reactome.org/PathwayBrowser/#/R-SCE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 18420 R-SCE-9853512 https://reactome.org/PathwayBrowser/#/R-SCE-9853512 DLST transfers succinyl to CoA IEA Saccharomyces cerevisiae 18420 R-SCE-9861616 https://reactome.org/PathwayBrowser/#/R-SCE-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 18420 R-SCE-9861667 https://reactome.org/PathwayBrowser/#/R-SCE-9861667 DLAT trimer transfers acetyl to CoA IEA Saccharomyces cerevisiae 18420 R-SCE-9861734 https://reactome.org/PathwayBrowser/#/R-SCE-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Saccharomyces cerevisiae 18420 R-SPO-109624 https://reactome.org/PathwayBrowser/#/R-SPO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Schizosaccharomyces pombe 18420 R-SPO-111215 https://reactome.org/PathwayBrowser/#/R-SPO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Schizosaccharomyces pombe 18420 R-SPO-111524 https://reactome.org/PathwayBrowser/#/R-SPO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Schizosaccharomyces pombe 18420 R-SPO-1237129 https://reactome.org/PathwayBrowser/#/R-SPO-1237129 Acireductone is created IEA Schizosaccharomyces pombe 18420 R-SPO-1482961 https://reactome.org/PathwayBrowser/#/R-SPO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Schizosaccharomyces pombe 18420 R-SPO-1482962 https://reactome.org/PathwayBrowser/#/R-SPO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Schizosaccharomyces pombe 18420 R-SPO-1482973 https://reactome.org/PathwayBrowser/#/R-SPO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Schizosaccharomyces pombe 18420 R-SPO-1482976 https://reactome.org/PathwayBrowser/#/R-SPO-1482976 CDP-DAG is converted to PI by CDIPT IEA Schizosaccharomyces pombe 18420 R-SPO-1483121 https://reactome.org/PathwayBrowser/#/R-SPO-1483121 PA is converted to CDP-DAG by CDS1 IEA Schizosaccharomyces pombe 18420 R-SPO-1483203 https://reactome.org/PathwayBrowser/#/R-SPO-1483203 PA is dephosphorylated to DAG by LPIN IEA Schizosaccharomyces pombe 18420 R-SPO-1606273 https://reactome.org/PathwayBrowser/#/R-SPO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Schizosaccharomyces pombe 18420 R-SPO-174391 https://reactome.org/PathwayBrowser/#/R-SPO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Schizosaccharomyces pombe 18420 R-SPO-174394 https://reactome.org/PathwayBrowser/#/R-SPO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Schizosaccharomyces pombe 18420 R-SPO-1855165 https://reactome.org/PathwayBrowser/#/R-SPO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 18420 R-SPO-1855166 https://reactome.org/PathwayBrowser/#/R-SPO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Schizosaccharomyces pombe 18420 R-SPO-1855198 https://reactome.org/PathwayBrowser/#/R-SPO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 18420 R-SPO-1855205 https://reactome.org/PathwayBrowser/#/R-SPO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Schizosaccharomyces pombe 18420 R-SPO-191303 https://reactome.org/PathwayBrowser/#/R-SPO-191303 FDPS dimer transfers IPPP to GPP IEA Schizosaccharomyces pombe 18420 R-SPO-191322 https://reactome.org/PathwayBrowser/#/R-SPO-191322 FDPS dimer transfers IPPP to DMAPP IEA Schizosaccharomyces pombe 18420 R-SPO-191382 https://reactome.org/PathwayBrowser/#/R-SPO-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Schizosaccharomyces pombe 18420 R-SPO-191402 https://reactome.org/PathwayBrowser/#/R-SPO-191402 Reduction of presqualene diphosphate to form squalene IEA Schizosaccharomyces pombe 18420 R-SPO-191405 https://reactome.org/PathwayBrowser/#/R-SPO-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Schizosaccharomyces pombe 18420 R-SPO-196761 https://reactome.org/PathwayBrowser/#/R-SPO-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Schizosaccharomyces pombe 18420 R-SPO-196964 https://reactome.org/PathwayBrowser/#/R-SPO-196964 RFK:Mg2+ phosphorylates RIB IEA Schizosaccharomyces pombe 18420 R-SPO-197186 https://reactome.org/PathwayBrowser/#/R-SPO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Schizosaccharomyces pombe 18420 R-SPO-197235 https://reactome.org/PathwayBrowser/#/R-SPO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 18420 R-SPO-200474 https://reactome.org/PathwayBrowser/#/R-SPO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 18420 R-SPO-2023971 https://reactome.org/PathwayBrowser/#/R-SPO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 18420 R-SPO-2023973 https://reactome.org/PathwayBrowser/#/R-SPO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 18420 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 18420 R-SPO-2162253 https://reactome.org/PathwayBrowser/#/R-SPO-2162253 PDSS1,2 ligates FPP to IPPP IEA Schizosaccharomyces pombe 18420 R-SPO-2393939 https://reactome.org/PathwayBrowser/#/R-SPO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Schizosaccharomyces pombe 18420 R-SPO-2408551 https://reactome.org/PathwayBrowser/#/R-SPO-2408551 SeMet is converted to AdoSeMet by MAT IEA Schizosaccharomyces pombe 18420 R-SPO-2509827 https://reactome.org/PathwayBrowser/#/R-SPO-2509827 ITPA hydrolyses ITP to IMP IEA Schizosaccharomyces pombe 18420 R-SPO-2509831 https://reactome.org/PathwayBrowser/#/R-SPO-2509831 ITPA hydrolyses XTP to XMP IEA Schizosaccharomyces pombe 18420 R-SPO-2509838 https://reactome.org/PathwayBrowser/#/R-SPO-2509838 ITPA hydrolyses dITP to dIMP IEA Schizosaccharomyces pombe 18420 R-SPO-389611 https://reactome.org/PathwayBrowser/#/R-SPO-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Schizosaccharomyces pombe 18420 R-SPO-449937 https://reactome.org/PathwayBrowser/#/R-SPO-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Schizosaccharomyces pombe 18420 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 18420 R-SPO-5336466 https://reactome.org/PathwayBrowser/#/R-SPO-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Schizosaccharomyces pombe 18420 R-SPO-5339528 https://reactome.org/PathwayBrowser/#/R-SPO-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Schizosaccharomyces pombe 18420 R-SPO-5339538 https://reactome.org/PathwayBrowser/#/R-SPO-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Schizosaccharomyces pombe 18420 R-SPO-5655835 https://reactome.org/PathwayBrowser/#/R-SPO-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Schizosaccharomyces pombe 18420 R-SPO-5655892 https://reactome.org/PathwayBrowser/#/R-SPO-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Schizosaccharomyces pombe 18420 R-SPO-5655965 https://reactome.org/PathwayBrowser/#/R-SPO-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Schizosaccharomyces pombe 18420 R-SPO-5656148 https://reactome.org/PathwayBrowser/#/R-SPO-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Schizosaccharomyces pombe 18420 R-SPO-5656158 https://reactome.org/PathwayBrowser/#/R-SPO-5656158 POLZ elongates POLI-incorporated dNMP IEA Schizosaccharomyces pombe 18420 R-SPO-5694018 https://reactome.org/PathwayBrowser/#/R-SPO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Schizosaccharomyces pombe 18420 R-SPO-5696074 https://reactome.org/PathwayBrowser/#/R-SPO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Schizosaccharomyces pombe 18420 R-SPO-6787329 https://reactome.org/PathwayBrowser/#/R-SPO-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Schizosaccharomyces pombe 18420 R-SPO-6788295 https://reactome.org/PathwayBrowser/#/R-SPO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Schizosaccharomyces pombe 18420 R-SPO-70349 https://reactome.org/PathwayBrowser/#/R-SPO-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Schizosaccharomyces pombe 18420 R-SPO-70479 https://reactome.org/PathwayBrowser/#/R-SPO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Schizosaccharomyces pombe 18420 R-SPO-70486 https://reactome.org/PathwayBrowser/#/R-SPO-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Schizosaccharomyces pombe 18420 R-SPO-70494 https://reactome.org/PathwayBrowser/#/R-SPO-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Schizosaccharomyces pombe 18420 R-SPO-70997 https://reactome.org/PathwayBrowser/#/R-SPO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Schizosaccharomyces pombe 18420 R-SPO-71401 https://reactome.org/PathwayBrowser/#/R-SPO-71401 OGDH dimer decarboxylates 2-OG IEA Schizosaccharomyces pombe 18420 R-SPO-71660 https://reactome.org/PathwayBrowser/#/R-SPO-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Schizosaccharomyces pombe 18420 R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 18420 R-SPO-71732 https://reactome.org/PathwayBrowser/#/R-SPO-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Schizosaccharomyces pombe 18420 R-SPO-71850 https://reactome.org/PathwayBrowser/#/R-SPO-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Schizosaccharomyces pombe 18420 R-SPO-73605 https://reactome.org/PathwayBrowser/#/R-SPO-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Schizosaccharomyces pombe 18420 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 18420 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 18420 R-SPO-8939959 https://reactome.org/PathwayBrowser/#/R-SPO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Schizosaccharomyces pombe 18420 R-SPO-8955760 https://reactome.org/PathwayBrowser/#/R-SPO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Schizosaccharomyces pombe 18420 R-SPO-8982667 https://reactome.org/PathwayBrowser/#/R-SPO-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Schizosaccharomyces pombe 18420 R-SPO-9012016 https://reactome.org/PathwayBrowser/#/R-SPO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Schizosaccharomyces pombe 18420 R-SPO-9014741 https://reactome.org/PathwayBrowser/#/R-SPO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Schizosaccharomyces pombe 18420 R-SPO-9014766 https://reactome.org/PathwayBrowser/#/R-SPO-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Schizosaccharomyces pombe 18420 R-SPO-936883 https://reactome.org/PathwayBrowser/#/R-SPO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Schizosaccharomyces pombe 18420 R-SPO-9638125 https://reactome.org/PathwayBrowser/#/R-SPO-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Schizosaccharomyces pombe 18420 R-SPO-9638127 https://reactome.org/PathwayBrowser/#/R-SPO-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Schizosaccharomyces pombe 18420 R-SPO-9717841 https://reactome.org/PathwayBrowser/#/R-SPO-9717841 holo-FDPS dimer binds NBPs IEA Schizosaccharomyces pombe 18420 R-SPO-9754974 https://reactome.org/PathwayBrowser/#/R-SPO-9754974 ADK phosphorylates RBV IEA Schizosaccharomyces pombe 18420 R-SPO-977324 https://reactome.org/PathwayBrowser/#/R-SPO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Schizosaccharomyces pombe 18420 R-SPO-983153 https://reactome.org/PathwayBrowser/#/R-SPO-983153 E1 mediated ubiquitin activation IEA Schizosaccharomyces pombe 18420 R-SPO-9853499 https://reactome.org/PathwayBrowser/#/R-SPO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 18420 R-SPO-9853512 https://reactome.org/PathwayBrowser/#/R-SPO-9853512 DLST transfers succinyl to CoA IEA Schizosaccharomyces pombe 18420 R-SPO-9861616 https://reactome.org/PathwayBrowser/#/R-SPO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 18420 R-SPO-9861667 https://reactome.org/PathwayBrowser/#/R-SPO-9861667 DLAT trimer transfers acetyl to CoA IEA Schizosaccharomyces pombe 18420 R-SPO-9861734 https://reactome.org/PathwayBrowser/#/R-SPO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Schizosaccharomyces pombe 18420 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 18420 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 18420 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 18420 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 18420 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 18420 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 18420 R-SSC-109624 https://reactome.org/PathwayBrowser/#/R-SSC-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Sus scrofa 18420 R-SSC-111215 https://reactome.org/PathwayBrowser/#/R-SSC-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Sus scrofa 18420 R-SSC-111524 https://reactome.org/PathwayBrowser/#/R-SSC-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Sus scrofa 18420 R-SSC-111930 https://reactome.org/PathwayBrowser/#/R-SSC-111930 Adenylate cyclase produces cAMP IEA Sus scrofa 18420 R-SSC-1237129 https://reactome.org/PathwayBrowser/#/R-SSC-1237129 Acireductone is created IEA Sus scrofa 18420 R-SSC-1482961 https://reactome.org/PathwayBrowser/#/R-SSC-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Sus scrofa 18420 R-SSC-1482962 https://reactome.org/PathwayBrowser/#/R-SSC-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Sus scrofa 18420 R-SSC-1482973 https://reactome.org/PathwayBrowser/#/R-SSC-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Sus scrofa 18420 R-SSC-1482976 https://reactome.org/PathwayBrowser/#/R-SSC-1482976 CDP-DAG is converted to PI by CDIPT IEA Sus scrofa 18420 R-SSC-1483096 https://reactome.org/PathwayBrowser/#/R-SSC-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Sus scrofa 18420 R-SSC-1483121 https://reactome.org/PathwayBrowser/#/R-SSC-1483121 PA is converted to CDP-DAG by CDS1 IEA Sus scrofa 18420 R-SSC-1483159 https://reactome.org/PathwayBrowser/#/R-SSC-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Sus scrofa 18420 R-SSC-1483203 https://reactome.org/PathwayBrowser/#/R-SSC-1483203 PA is dephosphorylated to DAG by LPIN IEA Sus scrofa 18420 R-SSC-1606273 https://reactome.org/PathwayBrowser/#/R-SSC-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Sus scrofa 18420 R-SSC-1606288 https://reactome.org/PathwayBrowser/#/R-SSC-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Sus scrofa 18420 R-SSC-163741 https://reactome.org/PathwayBrowser/#/R-SSC-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Sus scrofa 18420 R-SSC-163751 https://reactome.org/PathwayBrowser/#/R-SSC-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Sus scrofa 18420 R-SSC-1675928 https://reactome.org/PathwayBrowser/#/R-SSC-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Sus scrofa 18420 R-SSC-1675939 https://reactome.org/PathwayBrowser/#/R-SSC-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Sus scrofa 18420 R-SSC-1675961 https://reactome.org/PathwayBrowser/#/R-SSC-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Sus scrofa 18420 R-SSC-1676024 https://reactome.org/PathwayBrowser/#/R-SSC-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Sus scrofa 18420 R-SSC-1676109 https://reactome.org/PathwayBrowser/#/R-SSC-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Sus scrofa 18420 R-SSC-1676206 https://reactome.org/PathwayBrowser/#/R-SSC-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Sus scrofa 18420 R-SSC-170666 https://reactome.org/PathwayBrowser/#/R-SSC-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa 18420 R-SSC-170671 https://reactome.org/PathwayBrowser/#/R-SSC-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Sus scrofa 18420 R-SSC-170672 https://reactome.org/PathwayBrowser/#/R-SSC-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Sus scrofa 18420 R-SSC-170674 https://reactome.org/PathwayBrowser/#/R-SSC-170674 Dissociation of the Gi alpha:G olf complex IEA Sus scrofa 18420 R-SSC-170676 https://reactome.org/PathwayBrowser/#/R-SSC-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Sus scrofa 18420 R-SSC-170677 https://reactome.org/PathwayBrowser/#/R-SSC-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Sus scrofa 18420 R-SSC-170685 https://reactome.org/PathwayBrowser/#/R-SSC-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa 18420 R-SSC-170686 https://reactome.org/PathwayBrowser/#/R-SSC-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Sus scrofa 18420 R-SSC-174391 https://reactome.org/PathwayBrowser/#/R-SSC-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Sus scrofa 18420 R-SSC-174394 https://reactome.org/PathwayBrowser/#/R-SSC-174394 GSS:Mg2+ dimer synthesizes GSH IEA Sus scrofa 18420 R-SSC-1855154 https://reactome.org/PathwayBrowser/#/R-SSC-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 18420 R-SSC-1855159 https://reactome.org/PathwayBrowser/#/R-SSC-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Sus scrofa 18420 R-SSC-1855162 https://reactome.org/PathwayBrowser/#/R-SSC-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Sus scrofa 18420 R-SSC-1855165 https://reactome.org/PathwayBrowser/#/R-SSC-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 18420 R-SSC-1855166 https://reactome.org/PathwayBrowser/#/R-SSC-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Sus scrofa 18420 R-SSC-1855169 https://reactome.org/PathwayBrowser/#/R-SSC-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 18420 R-SSC-1855171 https://reactome.org/PathwayBrowser/#/R-SSC-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Sus scrofa 18420 R-SSC-1855172 https://reactome.org/PathwayBrowser/#/R-SSC-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Sus scrofa 18420 R-SSC-1855197 https://reactome.org/PathwayBrowser/#/R-SSC-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 18420 R-SSC-1855198 https://reactome.org/PathwayBrowser/#/R-SSC-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 18420 R-SSC-1855205 https://reactome.org/PathwayBrowser/#/R-SSC-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Sus scrofa 18420 R-SSC-1855208 https://reactome.org/PathwayBrowser/#/R-SSC-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Sus scrofa 18420 R-SSC-1855210 https://reactome.org/PathwayBrowser/#/R-SSC-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 18420 R-SSC-1855211 https://reactome.org/PathwayBrowser/#/R-SSC-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 18420 R-SSC-1855218 https://reactome.org/PathwayBrowser/#/R-SSC-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Sus scrofa 18420 R-SSC-1855219 https://reactome.org/PathwayBrowser/#/R-SSC-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 18420 R-SSC-1855232 https://reactome.org/PathwayBrowser/#/R-SSC-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Sus scrofa 18420 R-SSC-187688 https://reactome.org/PathwayBrowser/#/R-SSC-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Sus scrofa 18420 R-SSC-191303 https://reactome.org/PathwayBrowser/#/R-SSC-191303 FDPS dimer transfers IPPP to GPP IEA Sus scrofa 18420 R-SSC-191322 https://reactome.org/PathwayBrowser/#/R-SSC-191322 FDPS dimer transfers IPPP to DMAPP IEA Sus scrofa 18420 R-SSC-191382 https://reactome.org/PathwayBrowser/#/R-SSC-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Sus scrofa 18420 R-SSC-191402 https://reactome.org/PathwayBrowser/#/R-SSC-191402 Reduction of presqualene diphosphate to form squalene IEA Sus scrofa 18420 R-SSC-191405 https://reactome.org/PathwayBrowser/#/R-SSC-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Sus scrofa 18420 R-SSC-196761 https://reactome.org/PathwayBrowser/#/R-SSC-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Sus scrofa 18420 R-SSC-196964 https://reactome.org/PathwayBrowser/#/R-SSC-196964 RFK:Mg2+ phosphorylates RIB IEA Sus scrofa 18420 R-SSC-197186 https://reactome.org/PathwayBrowser/#/R-SSC-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Sus scrofa 18420 R-SSC-197235 https://reactome.org/PathwayBrowser/#/R-SSC-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 18420 R-SSC-200474 https://reactome.org/PathwayBrowser/#/R-SSC-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 18420 R-SSC-2023971 https://reactome.org/PathwayBrowser/#/R-SSC-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 18420 R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 18420 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 18420 R-SSC-204169 https://reactome.org/PathwayBrowser/#/R-SSC-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Sus scrofa 18420 R-SSC-2046085 https://reactome.org/PathwayBrowser/#/R-SSC-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Sus scrofa 18420 R-SSC-2046098 https://reactome.org/PathwayBrowser/#/R-SSC-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Sus scrofa 18420 R-SSC-216043 https://reactome.org/PathwayBrowser/#/R-SSC-216043 Collagen type II binds integrin alpha10beta1 IEA Sus scrofa 18420 R-SSC-216045 https://reactome.org/PathwayBrowser/#/R-SSC-216045 Collagen type I binds integrin alpha11beta1 IEA Sus scrofa 18420 R-SSC-216069 https://reactome.org/PathwayBrowser/#/R-SSC-216069 Interaction of integrin alphaDbeta2 with fibrin IEA Sus scrofa 18420 R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Sus scrofa 18420 R-SSC-2162066 https://reactome.org/PathwayBrowser/#/R-SSC-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Sus scrofa 18420 R-SSC-2162253 https://reactome.org/PathwayBrowser/#/R-SSC-2162253 PDSS1,2 ligates FPP to IPPP IEA Sus scrofa 18420 R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 18420 R-SSC-2393939 https://reactome.org/PathwayBrowser/#/R-SSC-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 18420 R-SSC-2393954 https://reactome.org/PathwayBrowser/#/R-SSC-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 18420 R-SSC-2395818 https://reactome.org/PathwayBrowser/#/R-SSC-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Sus scrofa 18420 R-SSC-2395849 https://reactome.org/PathwayBrowser/#/R-SSC-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 18420 R-SSC-2395872 https://reactome.org/PathwayBrowser/#/R-SSC-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Sus scrofa 18420 R-SSC-2408551 https://reactome.org/PathwayBrowser/#/R-SSC-2408551 SeMet is converted to AdoSeMet by MAT IEA Sus scrofa 18420 R-SSC-2509793 https://reactome.org/PathwayBrowser/#/R-SSC-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Sus scrofa 18420 R-SSC-2509816 https://reactome.org/PathwayBrowser/#/R-SSC-2509816 NUDT16 hydrolyses IDP to IMP IEA Sus scrofa 18420 R-SSC-2509827 https://reactome.org/PathwayBrowser/#/R-SSC-2509827 ITPA hydrolyses ITP to IMP IEA Sus scrofa 18420 R-SSC-2509831 https://reactome.org/PathwayBrowser/#/R-SSC-2509831 ITPA hydrolyses XTP to XMP IEA Sus scrofa 18420 R-SSC-2509838 https://reactome.org/PathwayBrowser/#/R-SSC-2509838 ITPA hydrolyses dITP to dIMP IEA Sus scrofa 18420 R-SSC-265682 https://reactome.org/PathwayBrowser/#/R-SSC-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Sus scrofa 18420 R-SSC-3322001 https://reactome.org/PathwayBrowser/#/R-SSC-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Sus scrofa 18420 R-SSC-3322003 https://reactome.org/PathwayBrowser/#/R-SSC-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Sus scrofa 18420 R-SSC-3322005 https://reactome.org/PathwayBrowser/#/R-SSC-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Sus scrofa 18420 R-SSC-3322009 https://reactome.org/PathwayBrowser/#/R-SSC-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Sus scrofa 18420 R-SSC-3322014 https://reactome.org/PathwayBrowser/#/R-SSC-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Sus scrofa 18420 R-SSC-3322016 https://reactome.org/PathwayBrowser/#/R-SSC-3322016 GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a IEA Sus scrofa 18420 R-SSC-3322019 https://reactome.org/PathwayBrowser/#/R-SSC-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Sus scrofa 18420 R-SSC-3322025 https://reactome.org/PathwayBrowser/#/R-SSC-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Sus scrofa 18420 R-SSC-3322041 https://reactome.org/PathwayBrowser/#/R-SSC-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Sus scrofa 18420 R-SSC-3322057 https://reactome.org/PathwayBrowser/#/R-SSC-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Sus scrofa 18420 R-SSC-354073 https://reactome.org/PathwayBrowser/#/R-SSC-354073 Autophosphorylation of PTK2 at Y397 IEA Sus scrofa 18420 R-SSC-354087 https://reactome.org/PathwayBrowser/#/R-SSC-354087 Recruitment of GRB2 to p-PTK2 IEA Sus scrofa 18420 R-SSC-354124 https://reactome.org/PathwayBrowser/#/R-SSC-354124 Phosphorylation of pPTK2 by SRC IEA Sus scrofa 18420 R-SSC-354149 https://reactome.org/PathwayBrowser/#/R-SSC-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Sus scrofa 18420 R-SSC-354165 https://reactome.org/PathwayBrowser/#/R-SSC-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Sus scrofa 18420 R-SSC-372693 https://reactome.org/PathwayBrowser/#/R-SSC-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Sus scrofa 18420 R-SSC-372697 https://reactome.org/PathwayBrowser/#/R-SSC-372697 Crk binding to p130cas IEA Sus scrofa 18420 R-SSC-372705 https://reactome.org/PathwayBrowser/#/R-SSC-372705 Recruitment of BCAR1 to PTK2 complex IEA Sus scrofa 18420 R-SSC-377640 https://reactome.org/PathwayBrowser/#/R-SSC-377640 Autophosphorylation of SRC IEA Sus scrofa 18420 R-SSC-377641 https://reactome.org/PathwayBrowser/#/R-SSC-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Sus scrofa 18420 R-SSC-377643 https://reactome.org/PathwayBrowser/#/R-SSC-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Sus scrofa 18420 R-SSC-377644 https://reactome.org/PathwayBrowser/#/R-SSC-377644 Release of CSK from SRC IEA Sus scrofa 18420 R-SSC-3780994 https://reactome.org/PathwayBrowser/#/R-SSC-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Sus scrofa 18420 R-SSC-3780997 https://reactome.org/PathwayBrowser/#/R-SSC-3780997 PPP1R3C binds to glycogen:GYG2:GYS2 IEA Sus scrofa 18420 R-SSC-3781011 https://reactome.org/PathwayBrowser/#/R-SSC-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Sus scrofa 18420 R-SSC-3781018 https://reactome.org/PathwayBrowser/#/R-SSC-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Sus scrofa 18420 R-SSC-3781023 https://reactome.org/PathwayBrowser/#/R-SSC-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Sus scrofa 18420 R-SSC-3781024 https://reactome.org/PathwayBrowser/#/R-SSC-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Sus scrofa 18420 R-SSC-3858495 https://reactome.org/PathwayBrowser/#/R-SSC-3858495 DAAM1 recruits GTP-bound RHOA IEA Sus scrofa 18420 R-SSC-389611 https://reactome.org/PathwayBrowser/#/R-SSC-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Sus scrofa 18420 R-SSC-392064 https://reactome.org/PathwayBrowser/#/R-SSC-392064 G alpha (z) inhibits adenylate cyclase IEA Sus scrofa 18420 R-SSC-4084989 https://reactome.org/PathwayBrowser/#/R-SSC-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Sus scrofa 18420 R-SSC-426223 https://reactome.org/PathwayBrowser/#/R-SSC-426223 Cation influx mediated by TRPC3/6/7 IEA Sus scrofa 18420 R-SSC-429415 https://reactome.org/PathwayBrowser/#/R-SSC-429415 SYK binds to integrin alphaIIb beta3 IEA Sus scrofa 18420 R-SSC-429441 https://reactome.org/PathwayBrowser/#/R-SSC-429441 SYK activation by SRC IEA Sus scrofa 18420 R-SSC-442661 https://reactome.org/PathwayBrowser/#/R-SSC-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol IEA Sus scrofa 18420 R-SSC-449937 https://reactome.org/PathwayBrowser/#/R-SSC-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Sus scrofa 18420 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 18420 R-SSC-5218804 https://reactome.org/PathwayBrowser/#/R-SSC-5218804 p38 MAPK activation by VEGFR IEA Sus scrofa 18420 R-SSC-5218826 https://reactome.org/PathwayBrowser/#/R-SSC-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Sus scrofa 18420 R-SSC-5228992 https://reactome.org/PathwayBrowser/#/R-SSC-5228992 ROCK1,ROCK2 are activated IEA Sus scrofa 18420 R-SSC-5336453 https://reactome.org/PathwayBrowser/#/R-SSC-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Sus scrofa 18420 R-SSC-5336466 https://reactome.org/PathwayBrowser/#/R-SSC-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Sus scrofa 18420 R-SSC-5339528 https://reactome.org/PathwayBrowser/#/R-SSC-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol IEA Sus scrofa 18420 R-SSC-5339538 https://reactome.org/PathwayBrowser/#/R-SSC-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol IEA Sus scrofa 18420 R-SSC-5603114 https://reactome.org/PathwayBrowser/#/R-SSC-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Sus scrofa 18420 R-SSC-5610727 https://reactome.org/PathwayBrowser/#/R-SSC-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Sus scrofa 18420 R-SSC-5655835 https://reactome.org/PathwayBrowser/#/R-SSC-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Sus scrofa 18420 R-SSC-5655892 https://reactome.org/PathwayBrowser/#/R-SSC-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Sus scrofa 18420 R-SSC-5655965 https://reactome.org/PathwayBrowser/#/R-SSC-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Sus scrofa 18420 R-SSC-5656105 https://reactome.org/PathwayBrowser/#/R-SSC-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Sus scrofa 18420 R-SSC-5656148 https://reactome.org/PathwayBrowser/#/R-SSC-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Sus scrofa 18420 R-SSC-5656158 https://reactome.org/PathwayBrowser/#/R-SSC-5656158 POLZ elongates POLI-incorporated dNMP IEA Sus scrofa 18420 R-SSC-5672972 https://reactome.org/PathwayBrowser/#/R-SSC-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Sus scrofa 18420 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 18420 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 18420 R-SSC-5672980 https://reactome.org/PathwayBrowser/#/R-SSC-5672980 Dissociation of RAS:RAF complex IEA Sus scrofa 18420 R-SSC-5694018 https://reactome.org/PathwayBrowser/#/R-SSC-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Sus scrofa 18420 R-SSC-5696021 https://reactome.org/PathwayBrowser/#/R-SSC-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Sus scrofa 18420 R-SSC-5696074 https://reactome.org/PathwayBrowser/#/R-SSC-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Sus scrofa 18420 R-SSC-6787329 https://reactome.org/PathwayBrowser/#/R-SSC-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Sus scrofa 18420 R-SSC-6788295 https://reactome.org/PathwayBrowser/#/R-SSC-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Sus scrofa 18420 R-SSC-6788597 https://reactome.org/PathwayBrowser/#/R-SSC-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Sus scrofa 18420 R-SSC-6788912 https://reactome.org/PathwayBrowser/#/R-SSC-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Sus scrofa 18420 R-SSC-70349 https://reactome.org/PathwayBrowser/#/R-SSC-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Sus scrofa 18420 R-SSC-70479 https://reactome.org/PathwayBrowser/#/R-SSC-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Sus scrofa 18420 R-SSC-70486 https://reactome.org/PathwayBrowser/#/R-SSC-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Sus scrofa 18420 R-SSC-70494 https://reactome.org/PathwayBrowser/#/R-SSC-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Sus scrofa 18420 R-SSC-70997 https://reactome.org/PathwayBrowser/#/R-SSC-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Sus scrofa 18420 R-SSC-71037 https://reactome.org/PathwayBrowser/#/R-SSC-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Sus scrofa 18420 R-SSC-71181 https://reactome.org/PathwayBrowser/#/R-SSC-71181 FAH cleaves 4FAA IEA Sus scrofa 18420 R-SSC-71324 https://reactome.org/PathwayBrowser/#/R-SSC-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 18420 R-SSC-71335 https://reactome.org/PathwayBrowser/#/R-SSC-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Sus scrofa 18420 R-SSC-71401 https://reactome.org/PathwayBrowser/#/R-SSC-71401 OGDH dimer decarboxylates 2-OG IEA Sus scrofa 18420 R-SSC-71660 https://reactome.org/PathwayBrowser/#/R-SSC-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Sus scrofa 18420 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 18420 R-SSC-71732 https://reactome.org/PathwayBrowser/#/R-SSC-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Sus scrofa 18420 R-SSC-71775 https://reactome.org/PathwayBrowser/#/R-SSC-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Sus scrofa 18420 R-SSC-71850 https://reactome.org/PathwayBrowser/#/R-SSC-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Sus scrofa 18420 R-SSC-73605 https://reactome.org/PathwayBrowser/#/R-SSC-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Sus scrofa 18420 R-SSC-74215 https://reactome.org/PathwayBrowser/#/R-SSC-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Sus scrofa 18420 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 18420 R-SSC-74948 https://reactome.org/PathwayBrowser/#/R-SSC-74948 PP2A dephosphorylates p-RHO to RHO IEA Sus scrofa 18420 R-SSC-8850846 https://reactome.org/PathwayBrowser/#/R-SSC-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Sus scrofa 18420 R-SSC-8850854 https://reactome.org/PathwayBrowser/#/R-SSC-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Sus scrofa 18420 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 18420 R-SSC-8851110 https://reactome.org/PathwayBrowser/#/R-SSC-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Sus scrofa 18420 R-SSC-8851129 https://reactome.org/PathwayBrowser/#/R-SSC-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Sus scrofa 18420 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 18420 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 18420 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 18420 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 18420 R-SSC-8939959 https://reactome.org/PathwayBrowser/#/R-SSC-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Sus scrofa 18420 R-SSC-8953499 https://reactome.org/PathwayBrowser/#/R-SSC-8953499 IMPAD1 hydrolyses PAP to AMP IEA Sus scrofa 18420 R-SSC-8955760 https://reactome.org/PathwayBrowser/#/R-SSC-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Sus scrofa 18420 R-SSC-8982667 https://reactome.org/PathwayBrowser/#/R-SSC-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Sus scrofa 18420 R-SSC-9012016 https://reactome.org/PathwayBrowser/#/R-SSC-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Sus scrofa 18420 R-SSC-9012036 https://reactome.org/PathwayBrowser/#/R-SSC-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Sus scrofa 18420 R-SSC-9012268 https://reactome.org/PathwayBrowser/#/R-SSC-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Sus scrofa 18420 R-SSC-9012349 https://reactome.org/PathwayBrowser/#/R-SSC-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Sus scrofa 18420 R-SSC-9014741 https://reactome.org/PathwayBrowser/#/R-SSC-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Sus scrofa 18420 R-SSC-9014766 https://reactome.org/PathwayBrowser/#/R-SSC-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Sus scrofa 18420 R-SSC-9024993 https://reactome.org/PathwayBrowser/#/R-SSC-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Sus scrofa 18420 R-SSC-936883 https://reactome.org/PathwayBrowser/#/R-SSC-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Sus scrofa 18420 R-SSC-947531 https://reactome.org/PathwayBrowser/#/R-SSC-947531 Molybdenum ion transfer onto molybdopterin IEA Sus scrofa 18420 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 18420 R-SSC-9621179 https://reactome.org/PathwayBrowser/#/R-SSC-9621179 Cinaciguat binds sGC:NO IEA Sus scrofa 18420 R-SSC-965067 https://reactome.org/PathwayBrowser/#/R-SSC-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Sus scrofa 18420 R-SSC-9650858 https://reactome.org/PathwayBrowser/#/R-SSC-9650858 Meglitinides bind ABCC8 IEA Sus scrofa 18420 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 18420 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa 18420 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa 18420 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 18420 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa 18420 R-SSC-9717830 https://reactome.org/PathwayBrowser/#/R-SSC-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Sus scrofa 18420 R-SSC-9717834 https://reactome.org/PathwayBrowser/#/R-SSC-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Sus scrofa 18420 R-SSC-9717841 https://reactome.org/PathwayBrowser/#/R-SSC-9717841 holo-FDPS dimer binds NBPs IEA Sus scrofa 18420 R-SSC-9731228 https://reactome.org/PathwayBrowser/#/R-SSC-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Sus scrofa 18420 R-SSC-9731590 https://reactome.org/PathwayBrowser/#/R-SSC-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Sus scrofa 18420 R-SSC-9731613 https://reactome.org/PathwayBrowser/#/R-SSC-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Sus scrofa 18420 R-SSC-9731632 https://reactome.org/PathwayBrowser/#/R-SSC-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Sus scrofa 18420 R-SSC-9748951 https://reactome.org/PathwayBrowser/#/R-SSC-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Sus scrofa 18420 R-SSC-9754916 https://reactome.org/PathwayBrowser/#/R-SSC-9754916 NT5C2 tetramer phosphorylates RBV IEA Sus scrofa 18420 R-SSC-9754974 https://reactome.org/PathwayBrowser/#/R-SSC-9754974 ADK phosphorylates RBV IEA Sus scrofa 18420 R-SSC-9755078 https://reactome.org/PathwayBrowser/#/R-SSC-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Sus scrofa 18420 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa 18420 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa 18420 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa 18420 R-SSC-977324 https://reactome.org/PathwayBrowser/#/R-SSC-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Sus scrofa 18420 R-SSC-983153 https://reactome.org/PathwayBrowser/#/R-SSC-983153 E1 mediated ubiquitin activation IEA Sus scrofa 18420 R-SSC-9853499 https://reactome.org/PathwayBrowser/#/R-SSC-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 18420 R-SSC-9853512 https://reactome.org/PathwayBrowser/#/R-SSC-9853512 DLST transfers succinyl to CoA IEA Sus scrofa 18420 R-SSC-9861616 https://reactome.org/PathwayBrowser/#/R-SSC-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 18420 R-SSC-9861631 https://reactome.org/PathwayBrowser/#/R-SSC-9861631 ME1 tetramerizes IEA Sus scrofa 18420 R-SSC-9861642 https://reactome.org/PathwayBrowser/#/R-SSC-9861642 NEK1 phosphorylates ME1 IEA Sus scrofa 18420 R-SSC-9861660 https://reactome.org/PathwayBrowser/#/R-SSC-9861660 ME1 tetramer decarboxylates OA to PYR IEA Sus scrofa 18420 R-SSC-9861667 https://reactome.org/PathwayBrowser/#/R-SSC-9861667 DLAT trimer transfers acetyl to CoA IEA Sus scrofa 18420 R-SSC-9861734 https://reactome.org/PathwayBrowser/#/R-SSC-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Sus scrofa 18420 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 18420 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 18420 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 18420 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 18420 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 18420 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 18420 R-XTR-109624 https://reactome.org/PathwayBrowser/#/R-XTR-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Xenopus tropicalis 18420 R-XTR-109671 https://reactome.org/PathwayBrowser/#/R-XTR-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Xenopus tropicalis 18420 R-XTR-111215 https://reactome.org/PathwayBrowser/#/R-XTR-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Xenopus tropicalis 18420 R-XTR-111524 https://reactome.org/PathwayBrowser/#/R-XTR-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Xenopus tropicalis 18420 R-XTR-111930 https://reactome.org/PathwayBrowser/#/R-XTR-111930 Adenylate cyclase produces cAMP IEA Xenopus tropicalis 18420 R-XTR-1237129 https://reactome.org/PathwayBrowser/#/R-XTR-1237129 Acireductone is created IEA Xenopus tropicalis 18420 R-XTR-1482961 https://reactome.org/PathwayBrowser/#/R-XTR-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Xenopus tropicalis 18420 R-XTR-1482962 https://reactome.org/PathwayBrowser/#/R-XTR-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Xenopus tropicalis 18420 R-XTR-1482973 https://reactome.org/PathwayBrowser/#/R-XTR-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Xenopus tropicalis 18420 R-XTR-1482976 https://reactome.org/PathwayBrowser/#/R-XTR-1482976 CDP-DAG is converted to PI by CDIPT IEA Xenopus tropicalis 18420 R-XTR-1483096 https://reactome.org/PathwayBrowser/#/R-XTR-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Xenopus tropicalis 18420 R-XTR-1483121 https://reactome.org/PathwayBrowser/#/R-XTR-1483121 PA is converted to CDP-DAG by CDS1 IEA Xenopus tropicalis 18420 R-XTR-1483159 https://reactome.org/PathwayBrowser/#/R-XTR-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Xenopus tropicalis 18420 R-XTR-1483203 https://reactome.org/PathwayBrowser/#/R-XTR-1483203 PA is dephosphorylated to DAG by LPIN IEA Xenopus tropicalis 18420 R-XTR-1606273 https://reactome.org/PathwayBrowser/#/R-XTR-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Xenopus tropicalis 18420 R-XTR-163741 https://reactome.org/PathwayBrowser/#/R-XTR-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Xenopus tropicalis 18420 R-XTR-163751 https://reactome.org/PathwayBrowser/#/R-XTR-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Xenopus tropicalis 18420 R-XTR-1675928 https://reactome.org/PathwayBrowser/#/R-XTR-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Xenopus tropicalis 18420 R-XTR-1675939 https://reactome.org/PathwayBrowser/#/R-XTR-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Xenopus tropicalis 18420 R-XTR-1675961 https://reactome.org/PathwayBrowser/#/R-XTR-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Xenopus tropicalis 18420 R-XTR-1676024 https://reactome.org/PathwayBrowser/#/R-XTR-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Xenopus tropicalis 18420 R-XTR-1676109 https://reactome.org/PathwayBrowser/#/R-XTR-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Xenopus tropicalis 18420 R-XTR-1676206 https://reactome.org/PathwayBrowser/#/R-XTR-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Xenopus tropicalis 18420 R-XTR-170666 https://reactome.org/PathwayBrowser/#/R-XTR-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Xenopus tropicalis 18420 R-XTR-170671 https://reactome.org/PathwayBrowser/#/R-XTR-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Xenopus tropicalis 18420 R-XTR-170672 https://reactome.org/PathwayBrowser/#/R-XTR-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Xenopus tropicalis 18420 R-XTR-170674 https://reactome.org/PathwayBrowser/#/R-XTR-170674 Dissociation of the Gi alpha:G olf complex IEA Xenopus tropicalis 18420 R-XTR-170676 https://reactome.org/PathwayBrowser/#/R-XTR-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Xenopus tropicalis 18420 R-XTR-170677 https://reactome.org/PathwayBrowser/#/R-XTR-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Xenopus tropicalis 18420 R-XTR-170685 https://reactome.org/PathwayBrowser/#/R-XTR-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Xenopus tropicalis 18420 R-XTR-170686 https://reactome.org/PathwayBrowser/#/R-XTR-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Xenopus tropicalis 18420 R-XTR-174391 https://reactome.org/PathwayBrowser/#/R-XTR-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Xenopus tropicalis 18420 R-XTR-1855154 https://reactome.org/PathwayBrowser/#/R-XTR-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855159 https://reactome.org/PathwayBrowser/#/R-XTR-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855162 https://reactome.org/PathwayBrowser/#/R-XTR-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855165 https://reactome.org/PathwayBrowser/#/R-XTR-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855166 https://reactome.org/PathwayBrowser/#/R-XTR-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855169 https://reactome.org/PathwayBrowser/#/R-XTR-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855171 https://reactome.org/PathwayBrowser/#/R-XTR-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855172 https://reactome.org/PathwayBrowser/#/R-XTR-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855197 https://reactome.org/PathwayBrowser/#/R-XTR-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855198 https://reactome.org/PathwayBrowser/#/R-XTR-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855205 https://reactome.org/PathwayBrowser/#/R-XTR-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855210 https://reactome.org/PathwayBrowser/#/R-XTR-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855211 https://reactome.org/PathwayBrowser/#/R-XTR-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855218 https://reactome.org/PathwayBrowser/#/R-XTR-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-1855219 https://reactome.org/PathwayBrowser/#/R-XTR-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 18420 R-XTR-191382 https://reactome.org/PathwayBrowser/#/R-XTR-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Xenopus tropicalis 18420 R-XTR-191402 https://reactome.org/PathwayBrowser/#/R-XTR-191402 Reduction of presqualene diphosphate to form squalene IEA Xenopus tropicalis 18420 R-XTR-191405 https://reactome.org/PathwayBrowser/#/R-XTR-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Xenopus tropicalis 18420 R-XTR-196761 https://reactome.org/PathwayBrowser/#/R-XTR-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Xenopus tropicalis 18420 R-XTR-196964 https://reactome.org/PathwayBrowser/#/R-XTR-196964 RFK:Mg2+ phosphorylates RIB IEA Xenopus tropicalis 18420 R-XTR-2023971 https://reactome.org/PathwayBrowser/#/R-XTR-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 18420 R-XTR-2023973 https://reactome.org/PathwayBrowser/#/R-XTR-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 18420 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 18420 R-XTR-2046085 https://reactome.org/PathwayBrowser/#/R-XTR-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Xenopus tropicalis 18420 R-XTR-2046098 https://reactome.org/PathwayBrowser/#/R-XTR-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Xenopus tropicalis 18420 R-XTR-216043 https://reactome.org/PathwayBrowser/#/R-XTR-216043 Collagen type II binds integrin alpha10beta1 IEA Xenopus tropicalis 18420 R-XTR-216045 https://reactome.org/PathwayBrowser/#/R-XTR-216045 Collagen type I binds integrin alpha11beta1 IEA Xenopus tropicalis 18420 R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Xenopus tropicalis 18420 R-XTR-2162066 https://reactome.org/PathwayBrowser/#/R-XTR-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Xenopus tropicalis 18420 R-XTR-2162253 https://reactome.org/PathwayBrowser/#/R-XTR-2162253 PDSS1,2 ligates FPP to IPPP IEA Xenopus tropicalis 18420 R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 18420 R-XTR-2393939 https://reactome.org/PathwayBrowser/#/R-XTR-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 18420 R-XTR-2393954 https://reactome.org/PathwayBrowser/#/R-XTR-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 18420 R-XTR-2395818 https://reactome.org/PathwayBrowser/#/R-XTR-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Xenopus tropicalis 18420 R-XTR-2395849 https://reactome.org/PathwayBrowser/#/R-XTR-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 18420 R-XTR-2395872 https://reactome.org/PathwayBrowser/#/R-XTR-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Xenopus tropicalis 18420 R-XTR-2408551 https://reactome.org/PathwayBrowser/#/R-XTR-2408551 SeMet is converted to AdoSeMet by MAT IEA Xenopus tropicalis 18420 R-XTR-2509793 https://reactome.org/PathwayBrowser/#/R-XTR-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Xenopus tropicalis 18420 R-XTR-2509816 https://reactome.org/PathwayBrowser/#/R-XTR-2509816 NUDT16 hydrolyses IDP to IMP IEA Xenopus tropicalis 18420 R-XTR-2509827 https://reactome.org/PathwayBrowser/#/R-XTR-2509827 ITPA hydrolyses ITP to IMP IEA Xenopus tropicalis 18420 R-XTR-2509831 https://reactome.org/PathwayBrowser/#/R-XTR-2509831 ITPA hydrolyses XTP to XMP IEA Xenopus tropicalis 18420 R-XTR-2509838 https://reactome.org/PathwayBrowser/#/R-XTR-2509838 ITPA hydrolyses dITP to dIMP IEA Xenopus tropicalis 18420 R-XTR-265682 https://reactome.org/PathwayBrowser/#/R-XTR-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Xenopus tropicalis 18420 R-XTR-3858495 https://reactome.org/PathwayBrowser/#/R-XTR-3858495 DAAM1 recruits GTP-bound RHOA IEA Xenopus tropicalis 18420 R-XTR-389611 https://reactome.org/PathwayBrowser/#/R-XTR-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Xenopus tropicalis 18420 R-XTR-392064 https://reactome.org/PathwayBrowser/#/R-XTR-392064 G alpha (z) inhibits adenylate cyclase IEA Xenopus tropicalis 18420 R-XTR-4084989 https://reactome.org/PathwayBrowser/#/R-XTR-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Xenopus tropicalis 18420 R-XTR-426223 https://reactome.org/PathwayBrowser/#/R-XTR-426223 Cation influx mediated by TRPC3/6/7 IEA Xenopus tropicalis 18420 R-XTR-442661 https://reactome.org/PathwayBrowser/#/R-XTR-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol IEA Xenopus tropicalis 18420 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 18420 R-XTR-5218804 https://reactome.org/PathwayBrowser/#/R-XTR-5218804 p38 MAPK activation by VEGFR IEA Xenopus tropicalis 18420 R-XTR-5228992 https://reactome.org/PathwayBrowser/#/R-XTR-5228992 ROCK1,ROCK2 are activated IEA Xenopus tropicalis 18420 R-XTR-5336453 https://reactome.org/PathwayBrowser/#/R-XTR-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Xenopus tropicalis 18420 R-XTR-5336466 https://reactome.org/PathwayBrowser/#/R-XTR-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Xenopus tropicalis 18420 R-XTR-5603114 https://reactome.org/PathwayBrowser/#/R-XTR-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Xenopus tropicalis 18420 R-XTR-5610727 https://reactome.org/PathwayBrowser/#/R-XTR-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Xenopus tropicalis 18420 R-XTR-5655892 https://reactome.org/PathwayBrowser/#/R-XTR-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Xenopus tropicalis 18420 R-XTR-5655965 https://reactome.org/PathwayBrowser/#/R-XTR-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Xenopus tropicalis 18420 R-XTR-5656105 https://reactome.org/PathwayBrowser/#/R-XTR-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Xenopus tropicalis 18420 R-XTR-5656148 https://reactome.org/PathwayBrowser/#/R-XTR-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Xenopus tropicalis 18420 R-XTR-5656158 https://reactome.org/PathwayBrowser/#/R-XTR-5656158 POLZ elongates POLI-incorporated dNMP IEA Xenopus tropicalis 18420 R-XTR-5694018 https://reactome.org/PathwayBrowser/#/R-XTR-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Xenopus tropicalis 18420 R-XTR-5696021 https://reactome.org/PathwayBrowser/#/R-XTR-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Xenopus tropicalis 18420 R-XTR-5696074 https://reactome.org/PathwayBrowser/#/R-XTR-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Xenopus tropicalis 18420 R-XTR-6787329 https://reactome.org/PathwayBrowser/#/R-XTR-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Xenopus tropicalis 18420 R-XTR-6788295 https://reactome.org/PathwayBrowser/#/R-XTR-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Xenopus tropicalis 18420 R-XTR-6788597 https://reactome.org/PathwayBrowser/#/R-XTR-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Xenopus tropicalis 18420 R-XTR-6788912 https://reactome.org/PathwayBrowser/#/R-XTR-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Xenopus tropicalis 18420 R-XTR-70479 https://reactome.org/PathwayBrowser/#/R-XTR-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Xenopus tropicalis 18420 R-XTR-70494 https://reactome.org/PathwayBrowser/#/R-XTR-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Xenopus tropicalis 18420 R-XTR-70997 https://reactome.org/PathwayBrowser/#/R-XTR-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Xenopus tropicalis 18420 R-XTR-71037 https://reactome.org/PathwayBrowser/#/R-XTR-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 18420 R-XTR-71181 https://reactome.org/PathwayBrowser/#/R-XTR-71181 FAH cleaves 4FAA IEA Xenopus tropicalis 18420 R-XTR-71324 https://reactome.org/PathwayBrowser/#/R-XTR-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 18420 R-XTR-71335 https://reactome.org/PathwayBrowser/#/R-XTR-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Xenopus tropicalis 18420 R-XTR-71401 https://reactome.org/PathwayBrowser/#/R-XTR-71401 OGDH dimer decarboxylates 2-OG IEA Xenopus tropicalis 18420 R-XTR-71660 https://reactome.org/PathwayBrowser/#/R-XTR-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Xenopus tropicalis 18420 R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 18420 R-XTR-71732 https://reactome.org/PathwayBrowser/#/R-XTR-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Xenopus tropicalis 18420 R-XTR-71775 https://reactome.org/PathwayBrowser/#/R-XTR-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Xenopus tropicalis 18420 R-XTR-73598 https://reactome.org/PathwayBrowser/#/R-XTR-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Xenopus tropicalis 18420 R-XTR-73605 https://reactome.org/PathwayBrowser/#/R-XTR-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Xenopus tropicalis 18420 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 18420 R-XTR-8850846 https://reactome.org/PathwayBrowser/#/R-XTR-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 18420 R-XTR-8850854 https://reactome.org/PathwayBrowser/#/R-XTR-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 18420 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 18420 R-XTR-8851110 https://reactome.org/PathwayBrowser/#/R-XTR-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 18420 R-XTR-8851129 https://reactome.org/PathwayBrowser/#/R-XTR-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 18420 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 18420 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 18420 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 18420 R-XTR-8953499 https://reactome.org/PathwayBrowser/#/R-XTR-8953499 IMPAD1 hydrolyses PAP to AMP IEA Xenopus tropicalis 18420 R-XTR-8955760 https://reactome.org/PathwayBrowser/#/R-XTR-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Xenopus tropicalis 18420 R-XTR-8982667 https://reactome.org/PathwayBrowser/#/R-XTR-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Xenopus tropicalis 18420 R-XTR-9012016 https://reactome.org/PathwayBrowser/#/R-XTR-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Xenopus tropicalis 18420 R-XTR-9012268 https://reactome.org/PathwayBrowser/#/R-XTR-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 18420 R-XTR-9012349 https://reactome.org/PathwayBrowser/#/R-XTR-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 18420 R-XTR-9014741 https://reactome.org/PathwayBrowser/#/R-XTR-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Xenopus tropicalis 18420 R-XTR-9014766 https://reactome.org/PathwayBrowser/#/R-XTR-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Xenopus tropicalis 18420 R-XTR-9024993 https://reactome.org/PathwayBrowser/#/R-XTR-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Xenopus tropicalis 18420 R-XTR-936883 https://reactome.org/PathwayBrowser/#/R-XTR-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Xenopus tropicalis 18420 R-XTR-965067 https://reactome.org/PathwayBrowser/#/R-XTR-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Xenopus tropicalis 18420 R-XTR-9650858 https://reactome.org/PathwayBrowser/#/R-XTR-9650858 Meglitinides bind ABCC8 IEA Xenopus tropicalis 18420 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 18420 R-XTR-9717830 https://reactome.org/PathwayBrowser/#/R-XTR-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Xenopus tropicalis 18420 R-XTR-9717834 https://reactome.org/PathwayBrowser/#/R-XTR-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Xenopus tropicalis 18420 R-XTR-9731228 https://reactome.org/PathwayBrowser/#/R-XTR-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Xenopus tropicalis 18420 R-XTR-9731590 https://reactome.org/PathwayBrowser/#/R-XTR-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Xenopus tropicalis 18420 R-XTR-9731613 https://reactome.org/PathwayBrowser/#/R-XTR-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Xenopus tropicalis 18420 R-XTR-9731632 https://reactome.org/PathwayBrowser/#/R-XTR-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Xenopus tropicalis 18420 R-XTR-9754916 https://reactome.org/PathwayBrowser/#/R-XTR-9754916 NT5C2 tetramer phosphorylates RBV IEA Xenopus tropicalis 18420 R-XTR-9754974 https://reactome.org/PathwayBrowser/#/R-XTR-9754974 ADK phosphorylates RBV IEA Xenopus tropicalis 18420 R-XTR-9755078 https://reactome.org/PathwayBrowser/#/R-XTR-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Xenopus tropicalis 18420 R-XTR-977324 https://reactome.org/PathwayBrowser/#/R-XTR-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Xenopus tropicalis 18420 R-XTR-983153 https://reactome.org/PathwayBrowser/#/R-XTR-983153 E1 mediated ubiquitin activation IEA Xenopus tropicalis 18420 R-XTR-9853499 https://reactome.org/PathwayBrowser/#/R-XTR-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 18420 R-XTR-9853512 https://reactome.org/PathwayBrowser/#/R-XTR-9853512 DLST transfers succinyl to CoA IEA Xenopus tropicalis 18420 R-XTR-9861616 https://reactome.org/PathwayBrowser/#/R-XTR-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 18420 R-XTR-9861667 https://reactome.org/PathwayBrowser/#/R-XTR-9861667 DLAT trimer transfers acetyl to CoA IEA Xenopus tropicalis 18420 R-XTR-9861734 https://reactome.org/PathwayBrowser/#/R-XTR-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Xenopus tropicalis 18421 R-BTA-1222376 https://reactome.org/PathwayBrowser/#/R-BTA-1222376 NOX2 generates superoxide from oxygen IEA Bos taurus 18421 R-BTA-1236967 https://reactome.org/PathwayBrowser/#/R-BTA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Bos taurus 18421 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 18421 R-BTA-3299680 https://reactome.org/PathwayBrowser/#/R-BTA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Bos taurus 18421 R-BTA-3299682 https://reactome.org/PathwayBrowser/#/R-BTA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Bos taurus 18421 R-BTA-3299691 https://reactome.org/PathwayBrowser/#/R-BTA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Bos taurus 18421 R-BTA-3341294 https://reactome.org/PathwayBrowser/#/R-BTA-3341294 Superoxide reduces cytochrome c IEA Bos taurus 18421 R-BTA-3777112 https://reactome.org/PathwayBrowser/#/R-BTA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Bos taurus 18421 R-BTA-5218841 https://reactome.org/PathwayBrowser/#/R-BTA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Bos taurus 18421 R-BTA-5668629 https://reactome.org/PathwayBrowser/#/R-BTA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Bos taurus 18421 R-BTA-5668718 https://reactome.org/PathwayBrowser/#/R-BTA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 18421 R-BTA-5668731 https://reactome.org/PathwayBrowser/#/R-BTA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 18421 R-BTA-6789092 https://reactome.org/PathwayBrowser/#/R-BTA-6789092 NOX2 generates superoxide anion from oxygen IEA Bos taurus 18421 R-BTA-6807557 https://reactome.org/PathwayBrowser/#/R-BTA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Bos taurus 18421 R-BTA-9709883 https://reactome.org/PathwayBrowser/#/R-BTA-9709883 BIL:ALB scavenges O2.- IEA Bos taurus 18421 R-BTA-9854368 https://reactome.org/PathwayBrowser/#/R-BTA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Bos taurus 18421 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 18421 R-CEL-3299680 https://reactome.org/PathwayBrowser/#/R-CEL-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Caenorhabditis elegans 18421 R-CEL-3299691 https://reactome.org/PathwayBrowser/#/R-CEL-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Caenorhabditis elegans 18421 R-CEL-3341294 https://reactome.org/PathwayBrowser/#/R-CEL-3341294 Superoxide reduces cytochrome c IEA Caenorhabditis elegans 18421 R-CEL-3777112 https://reactome.org/PathwayBrowser/#/R-CEL-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Caenorhabditis elegans 18421 R-CEL-9854368 https://reactome.org/PathwayBrowser/#/R-CEL-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Caenorhabditis elegans 18421 R-CFA-1222376 https://reactome.org/PathwayBrowser/#/R-CFA-1222376 NOX2 generates superoxide from oxygen IEA Canis familiaris 18421 R-CFA-1236967 https://reactome.org/PathwayBrowser/#/R-CFA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Canis familiaris 18421 R-CFA-3299680 https://reactome.org/PathwayBrowser/#/R-CFA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Canis familiaris 18421 R-CFA-3299682 https://reactome.org/PathwayBrowser/#/R-CFA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Canis familiaris 18421 R-CFA-3299691 https://reactome.org/PathwayBrowser/#/R-CFA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Canis familiaris 18421 R-CFA-3341294 https://reactome.org/PathwayBrowser/#/R-CFA-3341294 Superoxide reduces cytochrome c IEA Canis familiaris 18421 R-CFA-3777112 https://reactome.org/PathwayBrowser/#/R-CFA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Canis familiaris 18421 R-CFA-5218841 https://reactome.org/PathwayBrowser/#/R-CFA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Canis familiaris 18421 R-CFA-5668629 https://reactome.org/PathwayBrowser/#/R-CFA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Canis familiaris 18421 R-CFA-5668718 https://reactome.org/PathwayBrowser/#/R-CFA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 18421 R-CFA-5668731 https://reactome.org/PathwayBrowser/#/R-CFA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 18421 R-CFA-6789092 https://reactome.org/PathwayBrowser/#/R-CFA-6789092 NOX2 generates superoxide anion from oxygen IEA Canis familiaris 18421 R-CFA-6807557 https://reactome.org/PathwayBrowser/#/R-CFA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Canis familiaris 18421 R-CFA-9709883 https://reactome.org/PathwayBrowser/#/R-CFA-9709883 BIL:ALB scavenges O2.- IEA Canis familiaris 18421 R-CFA-9854368 https://reactome.org/PathwayBrowser/#/R-CFA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Canis familiaris 18421 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 18421 R-DDI-3299680 https://reactome.org/PathwayBrowser/#/R-DDI-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Dictyostelium discoideum 18421 R-DDI-3299682 https://reactome.org/PathwayBrowser/#/R-DDI-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Dictyostelium discoideum 18421 R-DDI-3299691 https://reactome.org/PathwayBrowser/#/R-DDI-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Dictyostelium discoideum 18421 R-DDI-3341294 https://reactome.org/PathwayBrowser/#/R-DDI-3341294 Superoxide reduces cytochrome c IEA Dictyostelium discoideum 18421 R-DDI-3777112 https://reactome.org/PathwayBrowser/#/R-DDI-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Dictyostelium discoideum 18421 R-DDI-6807557 https://reactome.org/PathwayBrowser/#/R-DDI-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Dictyostelium discoideum 18421 R-DDI-9854368 https://reactome.org/PathwayBrowser/#/R-DDI-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Dictyostelium discoideum 18421 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 18421 R-DME-3299680 https://reactome.org/PathwayBrowser/#/R-DME-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Drosophila melanogaster 18421 R-DME-3299691 https://reactome.org/PathwayBrowser/#/R-DME-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Drosophila melanogaster 18421 R-DME-3341294 https://reactome.org/PathwayBrowser/#/R-DME-3341294 Superoxide reduces cytochrome c IEA Drosophila melanogaster 18421 R-DME-3777112 https://reactome.org/PathwayBrowser/#/R-DME-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Drosophila melanogaster 18421 R-DME-6807557 https://reactome.org/PathwayBrowser/#/R-DME-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Drosophila melanogaster 18421 R-DME-9854368 https://reactome.org/PathwayBrowser/#/R-DME-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Drosophila melanogaster 18421 R-DRE-1222376 https://reactome.org/PathwayBrowser/#/R-DRE-1222376 NOX2 generates superoxide from oxygen IEA Danio rerio 18421 R-DRE-1236967 https://reactome.org/PathwayBrowser/#/R-DRE-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Danio rerio 18421 R-DRE-3299680 https://reactome.org/PathwayBrowser/#/R-DRE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Danio rerio 18421 R-DRE-3299682 https://reactome.org/PathwayBrowser/#/R-DRE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Danio rerio 18421 R-DRE-3299691 https://reactome.org/PathwayBrowser/#/R-DRE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Danio rerio 18421 R-DRE-3341294 https://reactome.org/PathwayBrowser/#/R-DRE-3341294 Superoxide reduces cytochrome c IEA Danio rerio 18421 R-DRE-3777112 https://reactome.org/PathwayBrowser/#/R-DRE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Danio rerio 18421 R-DRE-5218841 https://reactome.org/PathwayBrowser/#/R-DRE-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Danio rerio 18421 R-DRE-5668629 https://reactome.org/PathwayBrowser/#/R-DRE-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Danio rerio 18421 R-DRE-5668718 https://reactome.org/PathwayBrowser/#/R-DRE-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 18421 R-DRE-5668731 https://reactome.org/PathwayBrowser/#/R-DRE-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 18421 R-DRE-6789092 https://reactome.org/PathwayBrowser/#/R-DRE-6789092 NOX2 generates superoxide anion from oxygen IEA Danio rerio 18421 R-DRE-9854368 https://reactome.org/PathwayBrowser/#/R-DRE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Danio rerio 18421 R-GGA-1222376 https://reactome.org/PathwayBrowser/#/R-GGA-1222376 NOX2 generates superoxide from oxygen IEA Gallus gallus 18421 R-GGA-1236967 https://reactome.org/PathwayBrowser/#/R-GGA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Gallus gallus 18421 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 18421 R-GGA-3299680 https://reactome.org/PathwayBrowser/#/R-GGA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Gallus gallus 18421 R-GGA-3299682 https://reactome.org/PathwayBrowser/#/R-GGA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Gallus gallus 18421 R-GGA-3299691 https://reactome.org/PathwayBrowser/#/R-GGA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Gallus gallus 18421 R-GGA-3341294 https://reactome.org/PathwayBrowser/#/R-GGA-3341294 Superoxide reduces cytochrome c IEA Gallus gallus 18421 R-GGA-3777112 https://reactome.org/PathwayBrowser/#/R-GGA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Gallus gallus 18421 R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus 18421 R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus 18421 R-GGA-5668718 https://reactome.org/PathwayBrowser/#/R-GGA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 18421 R-GGA-5668731 https://reactome.org/PathwayBrowser/#/R-GGA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 18421 R-GGA-6789092 https://reactome.org/PathwayBrowser/#/R-GGA-6789092 NOX2 generates superoxide anion from oxygen IEA Gallus gallus 18421 R-GGA-6807557 https://reactome.org/PathwayBrowser/#/R-GGA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Gallus gallus 18421 R-GGA-9709883 https://reactome.org/PathwayBrowser/#/R-GGA-9709883 BIL:ALB scavenges O2.- IEA Gallus gallus 18421 R-GGA-9854368 https://reactome.org/PathwayBrowser/#/R-GGA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Gallus gallus 18421 R-HSA-1222353 https://reactome.org/PathwayBrowser/#/R-HSA-1222353 Protonation of superoxide TAS Homo sapiens 18421 R-HSA-1222376 https://reactome.org/PathwayBrowser/#/R-HSA-1222376 NOX2 generates superoxide from oxygen TAS Homo sapiens 18421 R-HSA-1222407 https://reactome.org/PathwayBrowser/#/R-HSA-1222407 Superoxide and nitric oxide react to peroxynitrite TAS Homo sapiens 18421 R-HSA-1222462 https://reactome.org/PathwayBrowser/#/R-HSA-1222462 SodB reduces superoxide to H2O2 TAS Homo sapiens 18421 R-HSA-1222469 https://reactome.org/PathwayBrowser/#/R-HSA-1222469 SodC reduces superoxide to H2O2 TAS Homo sapiens 18421 R-HSA-1236967 https://reactome.org/PathwayBrowser/#/R-HSA-1236967 Alkalization of the phagosomal lumen by NOX2 TAS Homo sapiens 18421 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 18421 R-HSA-1497878 https://reactome.org/PathwayBrowser/#/R-HSA-1497878 Superoxide reacts rapidly with NO to form peroxynitrite (ONOO-) TAS Homo sapiens 18421 R-HSA-3299680 https://reactome.org/PathwayBrowser/#/R-HSA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) TAS Homo sapiens 18421 R-HSA-3299682 https://reactome.org/PathwayBrowser/#/R-HSA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) TAS Homo sapiens 18421 R-HSA-3299691 https://reactome.org/PathwayBrowser/#/R-HSA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) TAS Homo sapiens 18421 R-HSA-3341294 https://reactome.org/PathwayBrowser/#/R-HSA-3341294 Superoxide reduces cytochrome c TAS Homo sapiens 18421 R-HSA-3697855 https://reactome.org/PathwayBrowser/#/R-HSA-3697855 Superoxide and nitric oxide react to form peroxynitrite in mitochondria TAS Homo sapiens 18421 R-HSA-3777112 https://reactome.org/PathwayBrowser/#/R-HSA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) TAS Homo sapiens 18421 R-HSA-5218841 https://reactome.org/PathwayBrowser/#/R-HSA-5218841 NADPH oxidase 2 generates superoxide from oxygen TAS Homo sapiens 18421 R-HSA-5668629 https://reactome.org/PathwayBrowser/#/R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP TAS Homo sapiens 18421 R-HSA-5668718 https://reactome.org/PathwayBrowser/#/R-HSA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 18421 R-HSA-5668731 https://reactome.org/PathwayBrowser/#/R-HSA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 18421 R-HSA-6788975 https://reactome.org/PathwayBrowser/#/R-HSA-6788975 Superoxide anion dismutates to H2O2 TAS Homo sapiens 18421 R-HSA-6789092 https://reactome.org/PathwayBrowser/#/R-HSA-6789092 NOX2 generates superoxide anion from oxygen TAS Homo sapiens 18421 R-HSA-6789109 https://reactome.org/PathwayBrowser/#/R-HSA-6789109 Superoxide anion reacts with Fe-S cluster TAS Homo sapiens 18421 R-HSA-6799733 https://reactome.org/PathwayBrowser/#/R-HSA-6799733 Semiquinone reacts with oxygen TAS Homo sapiens 18421 R-HSA-6807557 https://reactome.org/PathwayBrowser/#/R-HSA-6807557 NOX4, NOX5 reduce O2 to O2.- TAS Homo sapiens 18421 R-HSA-8942052 https://reactome.org/PathwayBrowser/#/R-HSA-8942052 Superoxide and nitric oxide react to peroxynitrite in the phagosome TAS Homo sapiens 18421 R-HSA-9673797 https://reactome.org/PathwayBrowser/#/R-HSA-9673797 NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 18421 R-HSA-9709879 https://reactome.org/PathwayBrowser/#/R-HSA-9709879 BIL scavenges O2.- TAS Homo sapiens 18421 R-HSA-9709883 https://reactome.org/PathwayBrowser/#/R-HSA-9709883 BIL:ALB scavenges O2.- TAS Homo sapiens 18421 R-HSA-9854368 https://reactome.org/PathwayBrowser/#/R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S TAS Homo sapiens 18421 R-MMU-1222376 https://reactome.org/PathwayBrowser/#/R-MMU-1222376 NOX2 generates superoxide from oxygen IEA Mus musculus 18421 R-MMU-1236967 https://reactome.org/PathwayBrowser/#/R-MMU-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Mus musculus 18421 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 18421 R-MMU-3299680 https://reactome.org/PathwayBrowser/#/R-MMU-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Mus musculus 18421 R-MMU-3299682 https://reactome.org/PathwayBrowser/#/R-MMU-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Mus musculus 18421 R-MMU-3299691 https://reactome.org/PathwayBrowser/#/R-MMU-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Mus musculus 18421 R-MMU-3341294 https://reactome.org/PathwayBrowser/#/R-MMU-3341294 Superoxide reduces cytochrome c IEA Mus musculus 18421 R-MMU-3777112 https://reactome.org/PathwayBrowser/#/R-MMU-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Mus musculus 18421 R-MMU-5218841 https://reactome.org/PathwayBrowser/#/R-MMU-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Mus musculus 18421 R-MMU-5668629 https://reactome.org/PathwayBrowser/#/R-MMU-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Mus musculus 18421 R-MMU-5668718 https://reactome.org/PathwayBrowser/#/R-MMU-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 18421 R-MMU-5668731 https://reactome.org/PathwayBrowser/#/R-MMU-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 18421 R-MMU-6789092 https://reactome.org/PathwayBrowser/#/R-MMU-6789092 NOX2 generates superoxide anion from oxygen IEA Mus musculus 18421 R-MMU-6807557 https://reactome.org/PathwayBrowser/#/R-MMU-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Mus musculus 18421 R-MMU-9709883 https://reactome.org/PathwayBrowser/#/R-MMU-9709883 BIL:ALB scavenges O2.- IEA Mus musculus 18421 R-MMU-9854368 https://reactome.org/PathwayBrowser/#/R-MMU-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Mus musculus 18421 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 18421 R-PFA-3341294 https://reactome.org/PathwayBrowser/#/R-PFA-3341294 Superoxide reduces cytochrome c IEA Plasmodium falciparum 18421 R-RNO-1222376 https://reactome.org/PathwayBrowser/#/R-RNO-1222376 NOX2 generates superoxide from oxygen IEA Rattus norvegicus 18421 R-RNO-1236967 https://reactome.org/PathwayBrowser/#/R-RNO-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Rattus norvegicus 18421 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 18421 R-RNO-3299680 https://reactome.org/PathwayBrowser/#/R-RNO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Rattus norvegicus 18421 R-RNO-3299682 https://reactome.org/PathwayBrowser/#/R-RNO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Rattus norvegicus 18421 R-RNO-3299691 https://reactome.org/PathwayBrowser/#/R-RNO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Rattus norvegicus 18421 R-RNO-3341294 https://reactome.org/PathwayBrowser/#/R-RNO-3341294 Superoxide reduces cytochrome c IEA Rattus norvegicus 18421 R-RNO-3777112 https://reactome.org/PathwayBrowser/#/R-RNO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Rattus norvegicus 18421 R-RNO-5218841 https://reactome.org/PathwayBrowser/#/R-RNO-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Rattus norvegicus 18421 R-RNO-5668629 https://reactome.org/PathwayBrowser/#/R-RNO-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Rattus norvegicus 18421 R-RNO-5668718 https://reactome.org/PathwayBrowser/#/R-RNO-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 18421 R-RNO-5668731 https://reactome.org/PathwayBrowser/#/R-RNO-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 18421 R-RNO-6789092 https://reactome.org/PathwayBrowser/#/R-RNO-6789092 NOX2 generates superoxide anion from oxygen IEA Rattus norvegicus 18421 R-RNO-6807557 https://reactome.org/PathwayBrowser/#/R-RNO-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Rattus norvegicus 18421 R-RNO-9709883 https://reactome.org/PathwayBrowser/#/R-RNO-9709883 BIL:ALB scavenges O2.- IEA Rattus norvegicus 18421 R-RNO-9854368 https://reactome.org/PathwayBrowser/#/R-RNO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Rattus norvegicus 18421 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 18421 R-SCE-3299680 https://reactome.org/PathwayBrowser/#/R-SCE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Saccharomyces cerevisiae 18421 R-SCE-3299682 https://reactome.org/PathwayBrowser/#/R-SCE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Saccharomyces cerevisiae 18421 R-SCE-3299691 https://reactome.org/PathwayBrowser/#/R-SCE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Saccharomyces cerevisiae 18421 R-SCE-3341294 https://reactome.org/PathwayBrowser/#/R-SCE-3341294 Superoxide reduces cytochrome c IEA Saccharomyces cerevisiae 18421 R-SCE-3777112 https://reactome.org/PathwayBrowser/#/R-SCE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Saccharomyces cerevisiae 18421 R-SCE-6807557 https://reactome.org/PathwayBrowser/#/R-SCE-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Saccharomyces cerevisiae 18421 R-SCE-9854368 https://reactome.org/PathwayBrowser/#/R-SCE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Saccharomyces cerevisiae 18421 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 18421 R-SPO-3299680 https://reactome.org/PathwayBrowser/#/R-SPO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Schizosaccharomyces pombe 18421 R-SPO-3299682 https://reactome.org/PathwayBrowser/#/R-SPO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Schizosaccharomyces pombe 18421 R-SPO-3299691 https://reactome.org/PathwayBrowser/#/R-SPO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Schizosaccharomyces pombe 18421 R-SPO-3341294 https://reactome.org/PathwayBrowser/#/R-SPO-3341294 Superoxide reduces cytochrome c IEA Schizosaccharomyces pombe 18421 R-SPO-3777112 https://reactome.org/PathwayBrowser/#/R-SPO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Schizosaccharomyces pombe 18421 R-SPO-9854368 https://reactome.org/PathwayBrowser/#/R-SPO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Schizosaccharomyces pombe 18421 R-SSC-1222376 https://reactome.org/PathwayBrowser/#/R-SSC-1222376 NOX2 generates superoxide from oxygen IEA Sus scrofa 18421 R-SSC-1236967 https://reactome.org/PathwayBrowser/#/R-SSC-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Sus scrofa 18421 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 18421 R-SSC-3299680 https://reactome.org/PathwayBrowser/#/R-SSC-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Sus scrofa 18421 R-SSC-3299682 https://reactome.org/PathwayBrowser/#/R-SSC-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Sus scrofa 18421 R-SSC-3299691 https://reactome.org/PathwayBrowser/#/R-SSC-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Sus scrofa 18421 R-SSC-3341294 https://reactome.org/PathwayBrowser/#/R-SSC-3341294 Superoxide reduces cytochrome c IEA Sus scrofa 18421 R-SSC-3777112 https://reactome.org/PathwayBrowser/#/R-SSC-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Sus scrofa 18421 R-SSC-5218841 https://reactome.org/PathwayBrowser/#/R-SSC-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Sus scrofa 18421 R-SSC-5668629 https://reactome.org/PathwayBrowser/#/R-SSC-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Sus scrofa 18421 R-SSC-5668718 https://reactome.org/PathwayBrowser/#/R-SSC-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 18421 R-SSC-5668731 https://reactome.org/PathwayBrowser/#/R-SSC-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 18421 R-SSC-6789092 https://reactome.org/PathwayBrowser/#/R-SSC-6789092 NOX2 generates superoxide anion from oxygen IEA Sus scrofa 18421 R-SSC-6807557 https://reactome.org/PathwayBrowser/#/R-SSC-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Sus scrofa 18421 R-SSC-9709883 https://reactome.org/PathwayBrowser/#/R-SSC-9709883 BIL:ALB scavenges O2.- IEA Sus scrofa 18421 R-SSC-9854368 https://reactome.org/PathwayBrowser/#/R-SSC-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Sus scrofa 18421 R-XTR-1222376 https://reactome.org/PathwayBrowser/#/R-XTR-1222376 NOX2 generates superoxide from oxygen IEA Xenopus tropicalis 18421 R-XTR-1236967 https://reactome.org/PathwayBrowser/#/R-XTR-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Xenopus tropicalis 18421 R-XTR-3299680 https://reactome.org/PathwayBrowser/#/R-XTR-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Xenopus tropicalis 18421 R-XTR-3299682 https://reactome.org/PathwayBrowser/#/R-XTR-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Xenopus tropicalis 18421 R-XTR-3299691 https://reactome.org/PathwayBrowser/#/R-XTR-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Xenopus tropicalis 18421 R-XTR-3341294 https://reactome.org/PathwayBrowser/#/R-XTR-3341294 Superoxide reduces cytochrome c IEA Xenopus tropicalis 18421 R-XTR-3777112 https://reactome.org/PathwayBrowser/#/R-XTR-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Xenopus tropicalis 18421 R-XTR-5218841 https://reactome.org/PathwayBrowser/#/R-XTR-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Xenopus tropicalis 18421 R-XTR-5668629 https://reactome.org/PathwayBrowser/#/R-XTR-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Xenopus tropicalis 18421 R-XTR-5668718 https://reactome.org/PathwayBrowser/#/R-XTR-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 18421 R-XTR-5668731 https://reactome.org/PathwayBrowser/#/R-XTR-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 18421 R-XTR-6789092 https://reactome.org/PathwayBrowser/#/R-XTR-6789092 NOX2 generates superoxide anion from oxygen IEA Xenopus tropicalis 18421 R-XTR-9709883 https://reactome.org/PathwayBrowser/#/R-XTR-9709883 BIL:ALB scavenges O2.- IEA Xenopus tropicalis 18421 R-XTR-9854368 https://reactome.org/PathwayBrowser/#/R-XTR-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Xenopus tropicalis 18431 R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 18431 R-BTA-193816 https://reactome.org/PathwayBrowser/#/R-BTA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Bos taurus 18431 R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 18431 R-CFA-193816 https://reactome.org/PathwayBrowser/#/R-CFA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Canis familiaris 18431 R-DRE-193816 https://reactome.org/PathwayBrowser/#/R-DRE-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Danio rerio 18431 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 18431 R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 18431 R-HSA-193816 https://reactome.org/PathwayBrowser/#/R-HSA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one TAS Homo sapiens 18431 R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 18431 R-MMU-193816 https://reactome.org/PathwayBrowser/#/R-MMU-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Mus musculus 18431 R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 18431 R-RNO-193816 https://reactome.org/PathwayBrowser/#/R-RNO-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Rattus norvegicus 18431 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 18431 R-SSC-193816 https://reactome.org/PathwayBrowser/#/R-SSC-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Sus scrofa 18431 R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 18431 R-XTR-193816 https://reactome.org/PathwayBrowser/#/R-XTR-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Xenopus tropicalis 18608 R-BTA-200652 https://reactome.org/PathwayBrowser/#/R-BTA-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Bos taurus 18608 R-BTA-200681 https://reactome.org/PathwayBrowser/#/R-BTA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Bos taurus 18608 R-BTA-3149539 https://reactome.org/PathwayBrowser/#/R-BTA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Bos taurus 18608 R-CEL-200652 https://reactome.org/PathwayBrowser/#/R-CEL-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Caenorhabditis elegans 18608 R-CEL-200681 https://reactome.org/PathwayBrowser/#/R-CEL-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Caenorhabditis elegans 18608 R-CEL-3149539 https://reactome.org/PathwayBrowser/#/R-CEL-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Caenorhabditis elegans 18608 R-CFA-200652 https://reactome.org/PathwayBrowser/#/R-CFA-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Canis familiaris 18608 R-CFA-200681 https://reactome.org/PathwayBrowser/#/R-CFA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Canis familiaris 18608 R-CFA-3149539 https://reactome.org/PathwayBrowser/#/R-CFA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Canis familiaris 18608 R-DDI-200652 https://reactome.org/PathwayBrowser/#/R-DDI-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Dictyostelium discoideum 18608 R-DDI-200681 https://reactome.org/PathwayBrowser/#/R-DDI-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Dictyostelium discoideum 18608 R-DDI-3149539 https://reactome.org/PathwayBrowser/#/R-DDI-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Dictyostelium discoideum 18608 R-DME-200652 https://reactome.org/PathwayBrowser/#/R-DME-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Drosophila melanogaster 18608 R-DME-200681 https://reactome.org/PathwayBrowser/#/R-DME-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Drosophila melanogaster 18608 R-DRE-200652 https://reactome.org/PathwayBrowser/#/R-DRE-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Danio rerio 18608 R-DRE-200681 https://reactome.org/PathwayBrowser/#/R-DRE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Danio rerio 18608 R-GGA-200652 https://reactome.org/PathwayBrowser/#/R-GGA-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Gallus gallus 18608 R-GGA-200681 https://reactome.org/PathwayBrowser/#/R-GGA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Gallus gallus 18608 R-GGA-3149539 https://reactome.org/PathwayBrowser/#/R-GGA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Gallus gallus 18608 R-HSA-200652 https://reactome.org/PathwayBrowser/#/R-HSA-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol TAS Homo sapiens 18608 R-HSA-200681 https://reactome.org/PathwayBrowser/#/R-HSA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG TAS Homo sapiens 18608 R-HSA-3149539 https://reactome.org/PathwayBrowser/#/R-HSA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin TAS Homo sapiens 18608 R-HSA-3321918 https://reactome.org/PathwayBrowser/#/R-HSA-3321918 Defective MTR does not transfer CH3 group from MTHF to cob(I)alamin TAS Homo sapiens 18608 R-MMU-200652 https://reactome.org/PathwayBrowser/#/R-MMU-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Mus musculus 18608 R-MMU-200681 https://reactome.org/PathwayBrowser/#/R-MMU-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Mus musculus 18608 R-MMU-3149539 https://reactome.org/PathwayBrowser/#/R-MMU-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Mus musculus 18608 R-RNO-200652 https://reactome.org/PathwayBrowser/#/R-RNO-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Rattus norvegicus 18608 R-RNO-200681 https://reactome.org/PathwayBrowser/#/R-RNO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Rattus norvegicus 18608 R-RNO-3149539 https://reactome.org/PathwayBrowser/#/R-RNO-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Rattus norvegicus 18608 R-SCE-200681 https://reactome.org/PathwayBrowser/#/R-SCE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Saccharomyces cerevisiae 18608 R-SPO-200681 https://reactome.org/PathwayBrowser/#/R-SPO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Schizosaccharomyces pombe 18608 R-SSC-200652 https://reactome.org/PathwayBrowser/#/R-SSC-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Sus scrofa 18608 R-SSC-200681 https://reactome.org/PathwayBrowser/#/R-SSC-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Sus scrofa 18608 R-SSC-3149539 https://reactome.org/PathwayBrowser/#/R-SSC-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Sus scrofa 18608 R-XTR-200652 https://reactome.org/PathwayBrowser/#/R-XTR-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Xenopus tropicalis 18608 R-XTR-200681 https://reactome.org/PathwayBrowser/#/R-XTR-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Xenopus tropicalis 1864 R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 1864 R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 1864 R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 1864 R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 1864 R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 1864 R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 1864 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 1864 R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 1864 R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 1864 R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 1864 R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa 1864 R-XTR-211991 https://reactome.org/PathwayBrowser/#/R-XTR-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Xenopus tropicalis 188347 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 188347 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 188347 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 188347 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 188347 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 188347 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 188347 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 188347 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 188347 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 188347 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 188348 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 188348 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 188348 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 188348 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 188348 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 188348 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 188348 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 188348 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 188348 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 188349 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 188349 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 188349 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 188349 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 188349 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 188349 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 188349 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 188349 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 188349 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 188349 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 188350 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 188350 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 188350 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 188350 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 188350 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 188350 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 188350 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 188350 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 188350 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 188350 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 188351 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 188351 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 188351 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 188351 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 188351 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 188351 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 188351 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 188351 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 188351 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 18898 R-BTA-9620103 https://reactome.org/PathwayBrowser/#/R-BTA-9620103 ALDH2 transforms GTN to NO IEA Bos taurus 18898 R-CEL-9620103 https://reactome.org/PathwayBrowser/#/R-CEL-9620103 ALDH2 transforms GTN to NO IEA Caenorhabditis elegans 18898 R-CFA-9620103 https://reactome.org/PathwayBrowser/#/R-CFA-9620103 ALDH2 transforms GTN to NO IEA Canis familiaris 18898 R-DDI-9620103 https://reactome.org/PathwayBrowser/#/R-DDI-9620103 ALDH2 transforms GTN to NO IEA Dictyostelium discoideum 18898 R-DME-9620103 https://reactome.org/PathwayBrowser/#/R-DME-9620103 ALDH2 transforms GTN to NO IEA Drosophila melanogaster 18898 R-DRE-9620103 https://reactome.org/PathwayBrowser/#/R-DRE-9620103 ALDH2 transforms GTN to NO IEA Danio rerio 18898 R-GGA-9620103 https://reactome.org/PathwayBrowser/#/R-GGA-9620103 ALDH2 transforms GTN to NO IEA Gallus gallus 18898 R-HSA-9620103 https://reactome.org/PathwayBrowser/#/R-HSA-9620103 ALDH2 transforms GTN to NO TAS Homo sapiens 18898 R-MMU-9620103 https://reactome.org/PathwayBrowser/#/R-MMU-9620103 ALDH2 transforms GTN to NO IEA Mus musculus 18898 R-RNO-9620103 https://reactome.org/PathwayBrowser/#/R-RNO-9620103 ALDH2 transforms GTN to NO IEA Rattus norvegicus 18898 R-SCE-9620103 https://reactome.org/PathwayBrowser/#/R-SCE-9620103 ALDH2 transforms GTN to NO IEA Saccharomyces cerevisiae 18898 R-SPO-9620103 https://reactome.org/PathwayBrowser/#/R-SPO-9620103 ALDH2 transforms GTN to NO IEA Schizosaccharomyces pombe 18898 R-SSC-9620103 https://reactome.org/PathwayBrowser/#/R-SSC-9620103 ALDH2 transforms GTN to NO IEA Sus scrofa 18898 R-XTR-9620103 https://reactome.org/PathwayBrowser/#/R-XTR-9620103 ALDH2 transforms GTN to NO IEA Xenopus tropicalis 189047 R-HSA-164504 https://reactome.org/PathwayBrowser/#/R-HSA-164504 Synthesis of minus strand strong stop DNA (-sssDNA) TAS Homo sapiens 189047 R-HSA-2162096 https://reactome.org/PathwayBrowser/#/R-HSA-2162096 carbovir diphosphate + ATP => carbovir triphosphate + ADP IEA Homo sapiens 189047 R-RNO-2162084 https://reactome.org/PathwayBrowser/#/R-RNO-2162084 carbovir diphosphate + ATP => carbovir triphosphate + ADP TAS Rattus norvegicus 189052 R-HSA-2162092 https://reactome.org/PathwayBrowser/#/R-HSA-2162092 carbovir monophosphate + ATP => carbovir diphosphate + ADP IEA Homo sapiens 189052 R-HSA-2162096 https://reactome.org/PathwayBrowser/#/R-HSA-2162096 carbovir diphosphate + ATP => carbovir triphosphate + ADP IEA Homo sapiens 189052 R-RNO-2162084 https://reactome.org/PathwayBrowser/#/R-RNO-2162084 carbovir diphosphate + ATP => carbovir triphosphate + ADP TAS Rattus norvegicus 189052 R-SSC-2162073 https://reactome.org/PathwayBrowser/#/R-SSC-2162073 carbovir monophosphate + ATP => carbovir diphosphate + ADP TAS Sus scrofa 189053 R-BTA-2161195 https://reactome.org/PathwayBrowser/#/R-BTA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Bos taurus 189053 R-BTA-2162066 https://reactome.org/PathwayBrowser/#/R-BTA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Bos taurus 189053 R-CEL-2161195 https://reactome.org/PathwayBrowser/#/R-CEL-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Caenorhabditis elegans 189053 R-CEL-2162066 https://reactome.org/PathwayBrowser/#/R-CEL-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Caenorhabditis elegans 189053 R-CFA-2161195 https://reactome.org/PathwayBrowser/#/R-CFA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Canis familiaris 189053 R-CFA-2162066 https://reactome.org/PathwayBrowser/#/R-CFA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Canis familiaris 189053 R-DDI-2162066 https://reactome.org/PathwayBrowser/#/R-DDI-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Dictyostelium discoideum 189053 R-DME-2161195 https://reactome.org/PathwayBrowser/#/R-DME-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Drosophila melanogaster 189053 R-DME-2162066 https://reactome.org/PathwayBrowser/#/R-DME-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Drosophila melanogaster 189053 R-DRE-2161195 https://reactome.org/PathwayBrowser/#/R-DRE-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Danio rerio 189053 R-GGA-2161195 https://reactome.org/PathwayBrowser/#/R-GGA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Gallus gallus 189053 R-GGA-2162066 https://reactome.org/PathwayBrowser/#/R-GGA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Gallus gallus 189053 R-HSA-2161195 https://reactome.org/PathwayBrowser/#/R-HSA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine TAS Homo sapiens 189053 R-HSA-2162066 https://reactome.org/PathwayBrowser/#/R-HSA-2162066 carbovir + IMP => carbovir monophosphate + inosine TAS Homo sapiens 189053 R-HSA-2162092 https://reactome.org/PathwayBrowser/#/R-HSA-2162092 carbovir monophosphate + ATP => carbovir diphosphate + ADP IEA Homo sapiens 189053 R-MMU-2161195 https://reactome.org/PathwayBrowser/#/R-MMU-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Mus musculus 189053 R-MMU-2162066 https://reactome.org/PathwayBrowser/#/R-MMU-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Mus musculus 189053 R-RNO-2162066 https://reactome.org/PathwayBrowser/#/R-RNO-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Rattus norvegicus 189053 R-SSC-2161195 https://reactome.org/PathwayBrowser/#/R-SSC-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Sus scrofa 189053 R-SSC-2162066 https://reactome.org/PathwayBrowser/#/R-SSC-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Sus scrofa 189053 R-SSC-2162073 https://reactome.org/PathwayBrowser/#/R-SSC-2162073 carbovir monophosphate + ATP => carbovir diphosphate + ADP TAS Sus scrofa 189053 R-XTR-2161195 https://reactome.org/PathwayBrowser/#/R-XTR-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Xenopus tropicalis 189053 R-XTR-2162066 https://reactome.org/PathwayBrowser/#/R-XTR-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Xenopus tropicalis 189091 R-BTA-9754916 https://reactome.org/PathwayBrowser/#/R-BTA-9754916 NT5C2 tetramer phosphorylates RBV IEA Bos taurus 189091 R-BTA-9754974 https://reactome.org/PathwayBrowser/#/R-BTA-9754974 ADK phosphorylates RBV IEA Bos taurus 189091 R-BTA-9755030 https://reactome.org/PathwayBrowser/#/R-BTA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Bos taurus 189091 R-BTA-9755078 https://reactome.org/PathwayBrowser/#/R-BTA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Bos taurus 189091 R-CEL-9754916 https://reactome.org/PathwayBrowser/#/R-CEL-9754916 NT5C2 tetramer phosphorylates RBV IEA Caenorhabditis elegans 189091 R-CEL-9754974 https://reactome.org/PathwayBrowser/#/R-CEL-9754974 ADK phosphorylates RBV IEA Caenorhabditis elegans 189091 R-CEL-9755030 https://reactome.org/PathwayBrowser/#/R-CEL-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Caenorhabditis elegans 189091 R-CEL-9755078 https://reactome.org/PathwayBrowser/#/R-CEL-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Caenorhabditis elegans 189091 R-CFA-9754916 https://reactome.org/PathwayBrowser/#/R-CFA-9754916 NT5C2 tetramer phosphorylates RBV IEA Canis familiaris 189091 R-CFA-9754974 https://reactome.org/PathwayBrowser/#/R-CFA-9754974 ADK phosphorylates RBV IEA Canis familiaris 189091 R-CFA-9755030 https://reactome.org/PathwayBrowser/#/R-CFA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Canis familiaris 189091 R-CFA-9755078 https://reactome.org/PathwayBrowser/#/R-CFA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Canis familiaris 189091 R-DDI-9754916 https://reactome.org/PathwayBrowser/#/R-DDI-9754916 NT5C2 tetramer phosphorylates RBV IEA Dictyostelium discoideum 189091 R-DDI-9754974 https://reactome.org/PathwayBrowser/#/R-DDI-9754974 ADK phosphorylates RBV IEA Dictyostelium discoideum 189091 R-DDI-9755030 https://reactome.org/PathwayBrowser/#/R-DDI-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Dictyostelium discoideum 189091 R-DDI-9755078 https://reactome.org/PathwayBrowser/#/R-DDI-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Dictyostelium discoideum 189091 R-DME-9754916 https://reactome.org/PathwayBrowser/#/R-DME-9754916 NT5C2 tetramer phosphorylates RBV IEA Drosophila melanogaster 189091 R-DME-9754974 https://reactome.org/PathwayBrowser/#/R-DME-9754974 ADK phosphorylates RBV IEA Drosophila melanogaster 189091 R-DME-9755030 https://reactome.org/PathwayBrowser/#/R-DME-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Drosophila melanogaster 189091 R-DME-9755078 https://reactome.org/PathwayBrowser/#/R-DME-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Drosophila melanogaster 189091 R-DRE-9754974 https://reactome.org/PathwayBrowser/#/R-DRE-9754974 ADK phosphorylates RBV IEA Danio rerio 189091 R-DRE-9755030 https://reactome.org/PathwayBrowser/#/R-DRE-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Danio rerio 189091 R-GGA-9754916 https://reactome.org/PathwayBrowser/#/R-GGA-9754916 NT5C2 tetramer phosphorylates RBV IEA Gallus gallus 189091 R-GGA-9754974 https://reactome.org/PathwayBrowser/#/R-GGA-9754974 ADK phosphorylates RBV IEA Gallus gallus 189091 R-GGA-9755030 https://reactome.org/PathwayBrowser/#/R-GGA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Gallus gallus 189091 R-GGA-9755078 https://reactome.org/PathwayBrowser/#/R-GGA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Gallus gallus 189091 R-HSA-9754916 https://reactome.org/PathwayBrowser/#/R-HSA-9754916 NT5C2 tetramer phosphorylates RBV TAS Homo sapiens 189091 R-HSA-9754974 https://reactome.org/PathwayBrowser/#/R-HSA-9754974 ADK phosphorylates RBV TAS Homo sapiens 189091 R-HSA-9754978 https://reactome.org/PathwayBrowser/#/R-HSA-9754978 Unknown kinase phosphorylates RBV-MP TAS Homo sapiens 189091 R-HSA-9755030 https://reactome.org/PathwayBrowser/#/R-HSA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP TAS Homo sapiens 189091 R-HSA-9755078 https://reactome.org/PathwayBrowser/#/R-HSA-9755078 NT5C2 tetramer dephosphorylates RBV-MP TAS Homo sapiens 189091 R-MMU-9754916 https://reactome.org/PathwayBrowser/#/R-MMU-9754916 NT5C2 tetramer phosphorylates RBV IEA Mus musculus 189091 R-MMU-9754974 https://reactome.org/PathwayBrowser/#/R-MMU-9754974 ADK phosphorylates RBV IEA Mus musculus 189091 R-MMU-9755030 https://reactome.org/PathwayBrowser/#/R-MMU-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Mus musculus 189091 R-MMU-9755078 https://reactome.org/PathwayBrowser/#/R-MMU-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Mus musculus 189091 R-PFA-9755030 https://reactome.org/PathwayBrowser/#/R-PFA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Plasmodium falciparum 189091 R-RNO-9754916 https://reactome.org/PathwayBrowser/#/R-RNO-9754916 NT5C2 tetramer phosphorylates RBV IEA Rattus norvegicus 189091 R-RNO-9754974 https://reactome.org/PathwayBrowser/#/R-RNO-9754974 ADK phosphorylates RBV IEA Rattus norvegicus 189091 R-RNO-9755030 https://reactome.org/PathwayBrowser/#/R-RNO-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Rattus norvegicus 189091 R-RNO-9755078 https://reactome.org/PathwayBrowser/#/R-RNO-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Rattus norvegicus 189091 R-SCE-9754974 https://reactome.org/PathwayBrowser/#/R-SCE-9754974 ADK phosphorylates RBV IEA Saccharomyces cerevisiae 189091 R-SCE-9755030 https://reactome.org/PathwayBrowser/#/R-SCE-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Saccharomyces cerevisiae 189091 R-SPO-9754974 https://reactome.org/PathwayBrowser/#/R-SPO-9754974 ADK phosphorylates RBV IEA Schizosaccharomyces pombe 189091 R-SPO-9755030 https://reactome.org/PathwayBrowser/#/R-SPO-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Schizosaccharomyces pombe 189091 R-SSC-9754916 https://reactome.org/PathwayBrowser/#/R-SSC-9754916 NT5C2 tetramer phosphorylates RBV IEA Sus scrofa 189091 R-SSC-9754974 https://reactome.org/PathwayBrowser/#/R-SSC-9754974 ADK phosphorylates RBV IEA Sus scrofa 189091 R-SSC-9755030 https://reactome.org/PathwayBrowser/#/R-SSC-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Sus scrofa 189091 R-SSC-9755078 https://reactome.org/PathwayBrowser/#/R-SSC-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Sus scrofa 189091 R-XTR-9754916 https://reactome.org/PathwayBrowser/#/R-XTR-9754916 NT5C2 tetramer phosphorylates RBV IEA Xenopus tropicalis 189091 R-XTR-9754974 https://reactome.org/PathwayBrowser/#/R-XTR-9754974 ADK phosphorylates RBV IEA Xenopus tropicalis 189091 R-XTR-9755030 https://reactome.org/PathwayBrowser/#/R-XTR-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Xenopus tropicalis 189091 R-XTR-9755078 https://reactome.org/PathwayBrowser/#/R-XTR-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Xenopus tropicalis 189092 R-BTA-9755013 https://reactome.org/PathwayBrowser/#/R-BTA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Bos taurus 189092 R-CEL-9755013 https://reactome.org/PathwayBrowser/#/R-CEL-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Caenorhabditis elegans 189092 R-CFA-9755013 https://reactome.org/PathwayBrowser/#/R-CFA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Canis familiaris 189092 R-DDI-9755013 https://reactome.org/PathwayBrowser/#/R-DDI-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Dictyostelium discoideum 189092 R-DME-9755013 https://reactome.org/PathwayBrowser/#/R-DME-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Drosophila melanogaster 189092 R-DRE-9755013 https://reactome.org/PathwayBrowser/#/R-DRE-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Danio rerio 189092 R-GGA-9755013 https://reactome.org/PathwayBrowser/#/R-GGA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Gallus gallus 189092 R-HSA-9754978 https://reactome.org/PathwayBrowser/#/R-HSA-9754978 Unknown kinase phosphorylates RBV-MP TAS Homo sapiens 189092 R-HSA-9755013 https://reactome.org/PathwayBrowser/#/R-HSA-9755013 NME1,2 hexamers phosphorylate RBV-DP TAS Homo sapiens 189092 R-MMU-9755013 https://reactome.org/PathwayBrowser/#/R-MMU-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Mus musculus 189092 R-PFA-9755013 https://reactome.org/PathwayBrowser/#/R-PFA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Plasmodium falciparum 189092 R-RNO-9755013 https://reactome.org/PathwayBrowser/#/R-RNO-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Rattus norvegicus 189092 R-SCE-9755013 https://reactome.org/PathwayBrowser/#/R-SCE-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Saccharomyces cerevisiae 189092 R-SPO-9755013 https://reactome.org/PathwayBrowser/#/R-SPO-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Schizosaccharomyces pombe 189092 R-SSC-9755013 https://reactome.org/PathwayBrowser/#/R-SSC-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Sus scrofa 189092 R-XTR-9755013 https://reactome.org/PathwayBrowser/#/R-XTR-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Xenopus tropicalis 189093 R-BTA-9754929 https://reactome.org/PathwayBrowser/#/R-BTA-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Bos taurus 189093 R-BTA-9755013 https://reactome.org/PathwayBrowser/#/R-BTA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Bos taurus 189093 R-BTA-9755030 https://reactome.org/PathwayBrowser/#/R-BTA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Bos taurus 189093 R-CEL-9754929 https://reactome.org/PathwayBrowser/#/R-CEL-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Caenorhabditis elegans 189093 R-CEL-9755013 https://reactome.org/PathwayBrowser/#/R-CEL-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Caenorhabditis elegans 189093 R-CEL-9755030 https://reactome.org/PathwayBrowser/#/R-CEL-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Caenorhabditis elegans 189093 R-CFA-9754929 https://reactome.org/PathwayBrowser/#/R-CFA-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Canis familiaris 189093 R-CFA-9755013 https://reactome.org/PathwayBrowser/#/R-CFA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Canis familiaris 189093 R-CFA-9755030 https://reactome.org/PathwayBrowser/#/R-CFA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Canis familiaris 189093 R-DDI-9754929 https://reactome.org/PathwayBrowser/#/R-DDI-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Dictyostelium discoideum 189093 R-DDI-9755013 https://reactome.org/PathwayBrowser/#/R-DDI-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Dictyostelium discoideum 189093 R-DDI-9755030 https://reactome.org/PathwayBrowser/#/R-DDI-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Dictyostelium discoideum 189093 R-DME-9754929 https://reactome.org/PathwayBrowser/#/R-DME-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Drosophila melanogaster 189093 R-DME-9755013 https://reactome.org/PathwayBrowser/#/R-DME-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Drosophila melanogaster 189093 R-DME-9755030 https://reactome.org/PathwayBrowser/#/R-DME-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Drosophila melanogaster 189093 R-DRE-9755013 https://reactome.org/PathwayBrowser/#/R-DRE-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Danio rerio 189093 R-DRE-9755030 https://reactome.org/PathwayBrowser/#/R-DRE-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Danio rerio 189093 R-GGA-9754929 https://reactome.org/PathwayBrowser/#/R-GGA-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Gallus gallus 189093 R-GGA-9755013 https://reactome.org/PathwayBrowser/#/R-GGA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Gallus gallus 189093 R-GGA-9755030 https://reactome.org/PathwayBrowser/#/R-GGA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Gallus gallus 189093 R-HSA-9754929 https://reactome.org/PathwayBrowser/#/R-HSA-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix TAS Homo sapiens 189093 R-HSA-9755013 https://reactome.org/PathwayBrowser/#/R-HSA-9755013 NME1,2 hexamers phosphorylate RBV-DP TAS Homo sapiens 189093 R-HSA-9755030 https://reactome.org/PathwayBrowser/#/R-HSA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP TAS Homo sapiens 189093 R-MMU-9754929 https://reactome.org/PathwayBrowser/#/R-MMU-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Mus musculus 189093 R-MMU-9755013 https://reactome.org/PathwayBrowser/#/R-MMU-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Mus musculus 189093 R-MMU-9755030 https://reactome.org/PathwayBrowser/#/R-MMU-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Mus musculus 189093 R-PFA-9754929 https://reactome.org/PathwayBrowser/#/R-PFA-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Plasmodium falciparum 189093 R-PFA-9755013 https://reactome.org/PathwayBrowser/#/R-PFA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Plasmodium falciparum 189093 R-PFA-9755030 https://reactome.org/PathwayBrowser/#/R-PFA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Plasmodium falciparum 189093 R-RNO-9754929 https://reactome.org/PathwayBrowser/#/R-RNO-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Rattus norvegicus 189093 R-RNO-9755013 https://reactome.org/PathwayBrowser/#/R-RNO-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Rattus norvegicus 189093 R-RNO-9755030 https://reactome.org/PathwayBrowser/#/R-RNO-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Rattus norvegicus 189093 R-SCE-9755013 https://reactome.org/PathwayBrowser/#/R-SCE-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Saccharomyces cerevisiae 189093 R-SCE-9755030 https://reactome.org/PathwayBrowser/#/R-SCE-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Saccharomyces cerevisiae 189093 R-SPO-9755013 https://reactome.org/PathwayBrowser/#/R-SPO-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Schizosaccharomyces pombe 189093 R-SPO-9755030 https://reactome.org/PathwayBrowser/#/R-SPO-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Schizosaccharomyces pombe 189093 R-SSC-9754929 https://reactome.org/PathwayBrowser/#/R-SSC-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Sus scrofa 189093 R-SSC-9755013 https://reactome.org/PathwayBrowser/#/R-SSC-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Sus scrofa 189093 R-SSC-9755030 https://reactome.org/PathwayBrowser/#/R-SSC-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Sus scrofa 189093 R-XTR-9755013 https://reactome.org/PathwayBrowser/#/R-XTR-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Xenopus tropicalis 189093 R-XTR-9755030 https://reactome.org/PathwayBrowser/#/R-XTR-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Xenopus tropicalis 18914 R-BTA-5693925 https://reactome.org/PathwayBrowser/#/R-BTA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Bos taurus 18914 R-CEL-5693925 https://reactome.org/PathwayBrowser/#/R-CEL-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Caenorhabditis elegans 18914 R-CFA-5693925 https://reactome.org/PathwayBrowser/#/R-CFA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Canis familiaris 18914 R-DDI-5693925 https://reactome.org/PathwayBrowser/#/R-DDI-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Dictyostelium discoideum 18914 R-DME-5693925 https://reactome.org/PathwayBrowser/#/R-DME-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Drosophila melanogaster 18914 R-HSA-5693925 https://reactome.org/PathwayBrowser/#/R-HSA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc TAS Homo sapiens 18914 R-SSC-5693925 https://reactome.org/PathwayBrowser/#/R-SSC-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Sus scrofa 18914 R-XTR-5693925 https://reactome.org/PathwayBrowser/#/R-XTR-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Xenopus tropicalis 18915 R-BTA-5693925 https://reactome.org/PathwayBrowser/#/R-BTA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Bos taurus 18915 R-CEL-5693925 https://reactome.org/PathwayBrowser/#/R-CEL-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Caenorhabditis elegans 18915 R-CFA-5693925 https://reactome.org/PathwayBrowser/#/R-CFA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Canis familiaris 18915 R-DDI-5693925 https://reactome.org/PathwayBrowser/#/R-DDI-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Dictyostelium discoideum 18915 R-DME-5693925 https://reactome.org/PathwayBrowser/#/R-DME-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Drosophila melanogaster 18915 R-HSA-5693925 https://reactome.org/PathwayBrowser/#/R-HSA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc TAS Homo sapiens 18915 R-SSC-5693925 https://reactome.org/PathwayBrowser/#/R-SSC-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Sus scrofa 18915 R-XTR-5693925 https://reactome.org/PathwayBrowser/#/R-XTR-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Xenopus tropicalis 189551 R-BTA-9754964 https://reactome.org/PathwayBrowser/#/R-BTA-9754964 ADA deamidates RBV IEA Bos taurus 189551 R-CEL-9754964 https://reactome.org/PathwayBrowser/#/R-CEL-9754964 ADA deamidates RBV IEA Caenorhabditis elegans 189551 R-CFA-9754964 https://reactome.org/PathwayBrowser/#/R-CFA-9754964 ADA deamidates RBV IEA Canis familiaris 189551 R-DDI-9754964 https://reactome.org/PathwayBrowser/#/R-DDI-9754964 ADA deamidates RBV IEA Dictyostelium discoideum 189551 R-DRE-9754964 https://reactome.org/PathwayBrowser/#/R-DRE-9754964 ADA deamidates RBV IEA Danio rerio 189551 R-GGA-9754964 https://reactome.org/PathwayBrowser/#/R-GGA-9754964 ADA deamidates RBV IEA Gallus gallus 189551 R-HSA-9754964 https://reactome.org/PathwayBrowser/#/R-HSA-9754964 ADA deamidates RBV TAS Homo sapiens 189551 R-MMU-9754964 https://reactome.org/PathwayBrowser/#/R-MMU-9754964 ADA deamidates RBV IEA Mus musculus 189551 R-PFA-9754964 https://reactome.org/PathwayBrowser/#/R-PFA-9754964 ADA deamidates RBV IEA Plasmodium falciparum 189551 R-RNO-9754964 https://reactome.org/PathwayBrowser/#/R-RNO-9754964 ADA deamidates RBV IEA Rattus norvegicus 189551 R-SSC-9754964 https://reactome.org/PathwayBrowser/#/R-SSC-9754964 ADA deamidates RBV IEA Sus scrofa 189551 R-XTR-9754964 https://reactome.org/PathwayBrowser/#/R-XTR-9754964 ADA deamidates RBV IEA Xenopus tropicalis 189572 R-BTA-9861626 https://reactome.org/PathwayBrowser/#/R-BTA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Bos taurus 189572 R-CEL-9861626 https://reactome.org/PathwayBrowser/#/R-CEL-9861626 SIRT4 cleaves lipoyl from DLAT IEA Caenorhabditis elegans 189572 R-CFA-9861626 https://reactome.org/PathwayBrowser/#/R-CFA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Canis familiaris 189572 R-DME-9861626 https://reactome.org/PathwayBrowser/#/R-DME-9861626 SIRT4 cleaves lipoyl from DLAT IEA Drosophila melanogaster 189572 R-DRE-9861626 https://reactome.org/PathwayBrowser/#/R-DRE-9861626 SIRT4 cleaves lipoyl from DLAT IEA Danio rerio 189572 R-GGA-9861626 https://reactome.org/PathwayBrowser/#/R-GGA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Gallus gallus 189572 R-HSA-9861626 https://reactome.org/PathwayBrowser/#/R-HSA-9861626 SIRT4 cleaves lipoyl from DLAT TAS Homo sapiens 189572 R-MMU-9861626 https://reactome.org/PathwayBrowser/#/R-MMU-9861626 SIRT4 cleaves lipoyl from DLAT IEA Mus musculus 189572 R-RNO-9861626 https://reactome.org/PathwayBrowser/#/R-RNO-9861626 SIRT4 cleaves lipoyl from DLAT IEA Rattus norvegicus 189572 R-SSC-9861626 https://reactome.org/PathwayBrowser/#/R-SSC-9861626 SIRT4 cleaves lipoyl from DLAT IEA Sus scrofa 189572 R-XTR-9861626 https://reactome.org/PathwayBrowser/#/R-XTR-9861626 SIRT4 cleaves lipoyl from DLAT IEA Xenopus tropicalis 19138 R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 19138 R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 19138 R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 19138 R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 19138 R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 19138 R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 19138 R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa 19138 R-XTR-211924 https://reactome.org/PathwayBrowser/#/R-XTR-211924 CYP4B1 12-hydroxylates ARA IEA Xenopus tropicalis 192484 R-BTA-9794120 https://reactome.org/PathwayBrowser/#/R-BTA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Bos taurus 192484 R-BTA-9794270 https://reactome.org/PathwayBrowser/#/R-BTA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Bos taurus 192484 R-BTA-9794444 https://reactome.org/PathwayBrowser/#/R-BTA-9794444 ALB binds Cipro IEA Bos taurus 192484 R-BTA-9794475 https://reactome.org/PathwayBrowser/#/R-BTA-9794475 Cipro:ALB dissociates IEA Bos taurus 192484 R-BTA-9794523 https://reactome.org/PathwayBrowser/#/R-BTA-9794523 SLC22A1 transports Cipro into renal cell IEA Bos taurus 192484 R-BTA-9794572 https://reactome.org/PathwayBrowser/#/R-BTA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Bos taurus 192484 R-BTA-9795207 https://reactome.org/PathwayBrowser/#/R-BTA-9795207 SLC22A1 transports Cipro into hepatic cell IEA Bos taurus 192484 R-CEL-9794120 https://reactome.org/PathwayBrowser/#/R-CEL-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Caenorhabditis elegans 192484 R-CEL-9794270 https://reactome.org/PathwayBrowser/#/R-CEL-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Caenorhabditis elegans 192484 R-CEL-9794523 https://reactome.org/PathwayBrowser/#/R-CEL-9794523 SLC22A1 transports Cipro into renal cell IEA Caenorhabditis elegans 192484 R-CEL-9794572 https://reactome.org/PathwayBrowser/#/R-CEL-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Caenorhabditis elegans 192484 R-CEL-9795207 https://reactome.org/PathwayBrowser/#/R-CEL-9795207 SLC22A1 transports Cipro into hepatic cell IEA Caenorhabditis elegans 192484 R-CFA-9794120 https://reactome.org/PathwayBrowser/#/R-CFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Canis familiaris 192484 R-CFA-9794270 https://reactome.org/PathwayBrowser/#/R-CFA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Canis familiaris 192484 R-CFA-9794444 https://reactome.org/PathwayBrowser/#/R-CFA-9794444 ALB binds Cipro IEA Canis familiaris 192484 R-CFA-9794475 https://reactome.org/PathwayBrowser/#/R-CFA-9794475 Cipro:ALB dissociates IEA Canis familiaris 192484 R-CFA-9794523 https://reactome.org/PathwayBrowser/#/R-CFA-9794523 SLC22A1 transports Cipro into renal cell IEA Canis familiaris 192484 R-CFA-9794572 https://reactome.org/PathwayBrowser/#/R-CFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Canis familiaris 192484 R-CFA-9795207 https://reactome.org/PathwayBrowser/#/R-CFA-9795207 SLC22A1 transports Cipro into hepatic cell IEA Canis familiaris 192484 R-DDI-9794120 https://reactome.org/PathwayBrowser/#/R-DDI-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Dictyostelium discoideum 192484 R-DDI-9794572 https://reactome.org/PathwayBrowser/#/R-DDI-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Dictyostelium discoideum 192484 R-DME-9794120 https://reactome.org/PathwayBrowser/#/R-DME-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Drosophila melanogaster 192484 R-DME-9794270 https://reactome.org/PathwayBrowser/#/R-DME-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Drosophila melanogaster 192484 R-DME-9794523 https://reactome.org/PathwayBrowser/#/R-DME-9794523 SLC22A1 transports Cipro into renal cell IEA Drosophila melanogaster 192484 R-DME-9794572 https://reactome.org/PathwayBrowser/#/R-DME-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Drosophila melanogaster 192484 R-DME-9795207 https://reactome.org/PathwayBrowser/#/R-DME-9795207 SLC22A1 transports Cipro into hepatic cell IEA Drosophila melanogaster 192484 R-DRE-9794270 https://reactome.org/PathwayBrowser/#/R-DRE-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Danio rerio 192484 R-DRE-9794523 https://reactome.org/PathwayBrowser/#/R-DRE-9794523 SLC22A1 transports Cipro into renal cell IEA Danio rerio 192484 R-DRE-9795207 https://reactome.org/PathwayBrowser/#/R-DRE-9795207 SLC22A1 transports Cipro into hepatic cell IEA Danio rerio 192484 R-GGA-9794270 https://reactome.org/PathwayBrowser/#/R-GGA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Gallus gallus 192484 R-GGA-9794444 https://reactome.org/PathwayBrowser/#/R-GGA-9794444 ALB binds Cipro IEA Gallus gallus 192484 R-GGA-9794475 https://reactome.org/PathwayBrowser/#/R-GGA-9794475 Cipro:ALB dissociates IEA Gallus gallus 192484 R-GGA-9794523 https://reactome.org/PathwayBrowser/#/R-GGA-9794523 SLC22A1 transports Cipro into renal cell IEA Gallus gallus 192484 R-GGA-9795207 https://reactome.org/PathwayBrowser/#/R-GGA-9795207 SLC22A1 transports Cipro into hepatic cell IEA Gallus gallus 192484 R-HSA-9793628 https://reactome.org/PathwayBrowser/#/R-HSA-9793628 Cipro is imported by organic cation transporters TAS Homo sapiens 192484 R-HSA-9794120 https://reactome.org/PathwayBrowser/#/R-HSA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space TAS Homo sapiens 192484 R-HSA-9794270 https://reactome.org/PathwayBrowser/#/R-HSA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol TAS Homo sapiens 192484 R-HSA-9794352 https://reactome.org/PathwayBrowser/#/R-HSA-9794352 Basolateral transport of Cipro into intestinal cell TAS Homo sapiens 192484 R-HSA-9794414 https://reactome.org/PathwayBrowser/#/R-HSA-9794414 Basolateral transport of Cipro to extracellular space TAS Homo sapiens 192484 R-HSA-9794444 https://reactome.org/PathwayBrowser/#/R-HSA-9794444 ALB binds Cipro TAS Homo sapiens 192484 R-HSA-9794475 https://reactome.org/PathwayBrowser/#/R-HSA-9794475 Cipro:ALB dissociates TAS Homo sapiens 192484 R-HSA-9794523 https://reactome.org/PathwayBrowser/#/R-HSA-9794523 SLC22A1 transports Cipro into renal cell TAS Homo sapiens 192484 R-HSA-9794569 https://reactome.org/PathwayBrowser/#/R-HSA-9794569 Apical transport of Cipro to extracellular space TAS Homo sapiens 192484 R-HSA-9794572 https://reactome.org/PathwayBrowser/#/R-HSA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space TAS Homo sapiens 192484 R-HSA-9794830 https://reactome.org/PathwayBrowser/#/R-HSA-9794830 SLC22A8 transports Cipro into renal cell IEA Homo sapiens 192484 R-HSA-9794840 https://reactome.org/PathwayBrowser/#/R-HSA-9794840 Cipro is oxidized to oxo-Cipro TAS Homo sapiens 192484 R-HSA-9795134 https://reactome.org/PathwayBrowser/#/R-HSA-9795134 Cipro is sulfonated to sulfo-Cipro TAS Homo sapiens 192484 R-HSA-9795207 https://reactome.org/PathwayBrowser/#/R-HSA-9795207 SLC22A1 transports Cipro into hepatic cell TAS Homo sapiens 192484 R-MMU-9794120 https://reactome.org/PathwayBrowser/#/R-MMU-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Mus musculus 192484 R-MMU-9794270 https://reactome.org/PathwayBrowser/#/R-MMU-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Mus musculus 192484 R-MMU-9794444 https://reactome.org/PathwayBrowser/#/R-MMU-9794444 ALB binds Cipro IEA Mus musculus 192484 R-MMU-9794475 https://reactome.org/PathwayBrowser/#/R-MMU-9794475 Cipro:ALB dissociates IEA Mus musculus 192484 R-MMU-9794523 https://reactome.org/PathwayBrowser/#/R-MMU-9794523 SLC22A1 transports Cipro into renal cell IEA Mus musculus 192484 R-MMU-9794572 https://reactome.org/PathwayBrowser/#/R-MMU-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Mus musculus 192484 R-MMU-9794643 https://reactome.org/PathwayBrowser/#/R-MMU-9794643 Slc22a8 transports Cipro into renal cell TAS Mus musculus 192484 R-MMU-9795207 https://reactome.org/PathwayBrowser/#/R-MMU-9795207 SLC22A1 transports Cipro into hepatic cell IEA Mus musculus 192484 R-PFA-9794120 https://reactome.org/PathwayBrowser/#/R-PFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Plasmodium falciparum 192484 R-PFA-9794572 https://reactome.org/PathwayBrowser/#/R-PFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Plasmodium falciparum 192484 R-RNO-9794120 https://reactome.org/PathwayBrowser/#/R-RNO-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Rattus norvegicus 192484 R-RNO-9794270 https://reactome.org/PathwayBrowser/#/R-RNO-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Rattus norvegicus 192484 R-RNO-9794444 https://reactome.org/PathwayBrowser/#/R-RNO-9794444 ALB binds Cipro IEA Rattus norvegicus 192484 R-RNO-9794475 https://reactome.org/PathwayBrowser/#/R-RNO-9794475 Cipro:ALB dissociates IEA Rattus norvegicus 192484 R-RNO-9794523 https://reactome.org/PathwayBrowser/#/R-RNO-9794523 SLC22A1 transports Cipro into renal cell IEA Rattus norvegicus 192484 R-RNO-9794572 https://reactome.org/PathwayBrowser/#/R-RNO-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Rattus norvegicus 192484 R-RNO-9795207 https://reactome.org/PathwayBrowser/#/R-RNO-9795207 SLC22A1 transports Cipro into hepatic cell IEA Rattus norvegicus 192484 R-SCE-9794120 https://reactome.org/PathwayBrowser/#/R-SCE-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Saccharomyces cerevisiae 192484 R-SCE-9794572 https://reactome.org/PathwayBrowser/#/R-SCE-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Saccharomyces cerevisiae 192484 R-SSC-9794120 https://reactome.org/PathwayBrowser/#/R-SSC-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Sus scrofa 192484 R-SSC-9794270 https://reactome.org/PathwayBrowser/#/R-SSC-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Sus scrofa 192484 R-SSC-9794444 https://reactome.org/PathwayBrowser/#/R-SSC-9794444 ALB binds Cipro IEA Sus scrofa 192484 R-SSC-9794475 https://reactome.org/PathwayBrowser/#/R-SSC-9794475 Cipro:ALB dissociates IEA Sus scrofa 192484 R-SSC-9794523 https://reactome.org/PathwayBrowser/#/R-SSC-9794523 SLC22A1 transports Cipro into renal cell IEA Sus scrofa 192484 R-SSC-9794572 https://reactome.org/PathwayBrowser/#/R-SSC-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Sus scrofa 192484 R-SSC-9795207 https://reactome.org/PathwayBrowser/#/R-SSC-9795207 SLC22A1 transports Cipro into hepatic cell IEA Sus scrofa 192484 R-XTR-9794120 https://reactome.org/PathwayBrowser/#/R-XTR-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Xenopus tropicalis 192484 R-XTR-9794444 https://reactome.org/PathwayBrowser/#/R-XTR-9794444 ALB binds Cipro IEA Xenopus tropicalis 192484 R-XTR-9794475 https://reactome.org/PathwayBrowser/#/R-XTR-9794475 Cipro:ALB dissociates IEA Xenopus tropicalis 192484 R-XTR-9794523 https://reactome.org/PathwayBrowser/#/R-XTR-9794523 SLC22A1 transports Cipro into renal cell IEA Xenopus tropicalis 192484 R-XTR-9794572 https://reactome.org/PathwayBrowser/#/R-XTR-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Xenopus tropicalis 192484 R-XTR-9795207 https://reactome.org/PathwayBrowser/#/R-XTR-9795207 SLC22A1 transports Cipro into hepatic cell IEA Xenopus tropicalis 192486 R-BTA-9794270 https://reactome.org/PathwayBrowser/#/R-BTA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Bos taurus 192486 R-CEL-9794270 https://reactome.org/PathwayBrowser/#/R-CEL-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Caenorhabditis elegans 192486 R-CFA-9794270 https://reactome.org/PathwayBrowser/#/R-CFA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Canis familiaris 192486 R-DME-9794270 https://reactome.org/PathwayBrowser/#/R-DME-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Drosophila melanogaster 192486 R-DRE-9794270 https://reactome.org/PathwayBrowser/#/R-DRE-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Danio rerio 192486 R-GGA-9794270 https://reactome.org/PathwayBrowser/#/R-GGA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Gallus gallus 192486 R-HSA-9793564 https://reactome.org/PathwayBrowser/#/R-HSA-9793564 Cipro HCl dissolves TAS Homo sapiens 192486 R-HSA-9793628 https://reactome.org/PathwayBrowser/#/R-HSA-9793628 Cipro is imported by organic cation transporters TAS Homo sapiens 192486 R-HSA-9794270 https://reactome.org/PathwayBrowser/#/R-HSA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol TAS Homo sapiens 192486 R-MMU-9794270 https://reactome.org/PathwayBrowser/#/R-MMU-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Mus musculus 192486 R-RNO-9794270 https://reactome.org/PathwayBrowser/#/R-RNO-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Rattus norvegicus 192486 R-SSC-9794270 https://reactome.org/PathwayBrowser/#/R-SSC-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Sus scrofa 192773 R-HSA-9794840 https://reactome.org/PathwayBrowser/#/R-HSA-9794840 Cipro is oxidized to oxo-Cipro TAS Homo sapiens 192773 R-HSA-9795153 https://reactome.org/PathwayBrowser/#/R-HSA-9795153 Basolateral excretion of oxo-Cipro TAS Homo sapiens 192798 R-HSA-9795134 https://reactome.org/PathwayBrowser/#/R-HSA-9795134 Cipro is sulfonated to sulfo-Cipro TAS Homo sapiens 192798 R-HSA-9795147 https://reactome.org/PathwayBrowser/#/R-HSA-9795147 Apical excretion of sulfo-Cipro TAS Homo sapiens 19324 R-BTA-6798335 https://reactome.org/PathwayBrowser/#/R-BTA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Bos taurus 19324 R-CFA-6798335 https://reactome.org/PathwayBrowser/#/R-CFA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Canis familiaris 19324 R-DDI-6798335 https://reactome.org/PathwayBrowser/#/R-DDI-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Dictyostelium discoideum 19324 R-DME-6798335 https://reactome.org/PathwayBrowser/#/R-DME-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Drosophila melanogaster 19324 R-DRE-6798335 https://reactome.org/PathwayBrowser/#/R-DRE-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Danio rerio 19324 R-GGA-6798335 https://reactome.org/PathwayBrowser/#/R-GGA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Gallus gallus 19324 R-HSA-6798335 https://reactome.org/PathwayBrowser/#/R-HSA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG TAS Homo sapiens 19324 R-MMU-6798335 https://reactome.org/PathwayBrowser/#/R-MMU-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Mus musculus 19324 R-PFA-6798335 https://reactome.org/PathwayBrowser/#/R-PFA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Plasmodium falciparum 19324 R-RNO-6798335 https://reactome.org/PathwayBrowser/#/R-RNO-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Rattus norvegicus 19324 R-SPO-6798335 https://reactome.org/PathwayBrowser/#/R-SPO-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Schizosaccharomyces pombe 19324 R-SSC-6798335 https://reactome.org/PathwayBrowser/#/R-SSC-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Sus scrofa 19324 R-XTR-6798335 https://reactome.org/PathwayBrowser/#/R-XTR-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Xenopus tropicalis 195408 R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus 195408 R-BTA-1605632 https://reactome.org/PathwayBrowser/#/R-BTA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Bos taurus 195408 R-BTA-1605724 https://reactome.org/PathwayBrowser/#/R-BTA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Bos taurus 195408 R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus 195408 R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus 195408 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 195408 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 195408 R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 195408 R-BTA-9842115 https://reactome.org/PathwayBrowser/#/R-BTA-9842115 PSAP(195-273) dimer binds PE IEA Bos taurus 195408 R-CEL-1605624 https://reactome.org/PathwayBrowser/#/R-CEL-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Caenorhabditis elegans 195408 R-CEL-1605632 https://reactome.org/PathwayBrowser/#/R-CEL-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Caenorhabditis elegans 195408 R-CEL-1605736 https://reactome.org/PathwayBrowser/#/R-CEL-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Caenorhabditis elegans 195408 R-CEL-1606312 https://reactome.org/PathwayBrowser/#/R-CEL-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Caenorhabditis elegans 195408 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 195408 R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 195408 R-CEL-9842115 https://reactome.org/PathwayBrowser/#/R-CEL-9842115 PSAP(195-273) dimer binds PE IEA Caenorhabditis elegans 195408 R-CFA-1605624 https://reactome.org/PathwayBrowser/#/R-CFA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Canis familiaris 195408 R-CFA-1605632 https://reactome.org/PathwayBrowser/#/R-CFA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Canis familiaris 195408 R-CFA-1605724 https://reactome.org/PathwayBrowser/#/R-CFA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Canis familiaris 195408 R-CFA-1605736 https://reactome.org/PathwayBrowser/#/R-CFA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Canis familiaris 195408 R-CFA-1606312 https://reactome.org/PathwayBrowser/#/R-CFA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Canis familiaris 195408 R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 195408 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 195408 R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 195408 R-CFA-9842115 https://reactome.org/PathwayBrowser/#/R-CFA-9842115 PSAP(195-273) dimer binds PE IEA Canis familiaris 195408 R-DDI-1605624 https://reactome.org/PathwayBrowser/#/R-DDI-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Dictyostelium discoideum 195408 R-DDI-1605632 https://reactome.org/PathwayBrowser/#/R-DDI-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Dictyostelium discoideum 195408 R-DDI-1605736 https://reactome.org/PathwayBrowser/#/R-DDI-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Dictyostelium discoideum 195408 R-DDI-1606312 https://reactome.org/PathwayBrowser/#/R-DDI-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Dictyostelium discoideum 195408 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 195408 R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 195408 R-DDI-9842115 https://reactome.org/PathwayBrowser/#/R-DDI-9842115 PSAP(195-273) dimer binds PE IEA Dictyostelium discoideum 195408 R-DME-1605624 https://reactome.org/PathwayBrowser/#/R-DME-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Drosophila melanogaster 195408 R-DME-1605632 https://reactome.org/PathwayBrowser/#/R-DME-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Drosophila melanogaster 195408 R-DME-1606312 https://reactome.org/PathwayBrowser/#/R-DME-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Drosophila melanogaster 195408 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 195408 R-DME-9842115 https://reactome.org/PathwayBrowser/#/R-DME-9842115 PSAP(195-273) dimer binds PE IEA Drosophila melanogaster 195408 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus 195408 R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus 195408 R-GGA-1605724 https://reactome.org/PathwayBrowser/#/R-GGA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Gallus gallus 195408 R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus 195408 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus 195408 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 195408 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 195408 R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 195408 R-GGA-9842115 https://reactome.org/PathwayBrowser/#/R-GGA-9842115 PSAP(195-273) dimer binds PE IEA Gallus gallus 195408 R-HSA-1605624 https://reactome.org/PathwayBrowser/#/R-HSA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 TAS Homo sapiens 195408 R-HSA-1605632 https://reactome.org/PathwayBrowser/#/R-HSA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE TAS Homo sapiens 195408 R-HSA-1605724 https://reactome.org/PathwayBrowser/#/R-HSA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE TAS Homo sapiens 195408 R-HSA-1605736 https://reactome.org/PathwayBrowser/#/R-HSA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE TAS Homo sapiens 195408 R-HSA-1606312 https://reactome.org/PathwayBrowser/#/R-HSA-1606312 GLB1 hydrolyzes SapB/C:LacCer TAS Homo sapiens 195408 R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 195408 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 195408 R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 195408 R-HSA-9842115 https://reactome.org/PathwayBrowser/#/R-HSA-9842115 PSAP(195-273) dimer binds PE TAS Homo sapiens 195408 R-MMU-1605624 https://reactome.org/PathwayBrowser/#/R-MMU-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Mus musculus 195408 R-MMU-1605632 https://reactome.org/PathwayBrowser/#/R-MMU-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Mus musculus 195408 R-MMU-1605724 https://reactome.org/PathwayBrowser/#/R-MMU-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Mus musculus 195408 R-MMU-1605736 https://reactome.org/PathwayBrowser/#/R-MMU-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Mus musculus 195408 R-MMU-1606312 https://reactome.org/PathwayBrowser/#/R-MMU-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Mus musculus 195408 R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 195408 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 195408 R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 195408 R-MMU-9842115 https://reactome.org/PathwayBrowser/#/R-MMU-9842115 PSAP(195-273) dimer binds PE IEA Mus musculus 195408 R-RNO-1605624 https://reactome.org/PathwayBrowser/#/R-RNO-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Rattus norvegicus 195408 R-RNO-1605632 https://reactome.org/PathwayBrowser/#/R-RNO-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Rattus norvegicus 195408 R-RNO-1605724 https://reactome.org/PathwayBrowser/#/R-RNO-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Rattus norvegicus 195408 R-RNO-1605736 https://reactome.org/PathwayBrowser/#/R-RNO-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Rattus norvegicus 195408 R-RNO-1606312 https://reactome.org/PathwayBrowser/#/R-RNO-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Rattus norvegicus 195408 R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 195408 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 195408 R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 195408 R-RNO-9842115 https://reactome.org/PathwayBrowser/#/R-RNO-9842115 PSAP(195-273) dimer binds PE IEA Rattus norvegicus 195408 R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa 195408 R-SSC-1605632 https://reactome.org/PathwayBrowser/#/R-SSC-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Sus scrofa 195408 R-SSC-1605724 https://reactome.org/PathwayBrowser/#/R-SSC-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Sus scrofa 195408 R-SSC-1605736 https://reactome.org/PathwayBrowser/#/R-SSC-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Sus scrofa 195408 R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa 195408 R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 195408 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 195408 R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 195408 R-SSC-9842115 https://reactome.org/PathwayBrowser/#/R-SSC-9842115 PSAP(195-273) dimer binds PE IEA Sus scrofa 195410 R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus 195410 R-BTA-1605632 https://reactome.org/PathwayBrowser/#/R-BTA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Bos taurus 195410 R-BTA-1605724 https://reactome.org/PathwayBrowser/#/R-BTA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Bos taurus 195410 R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus 195410 R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus 195410 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 195410 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 195410 R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 195410 R-BTA-9842115 https://reactome.org/PathwayBrowser/#/R-BTA-9842115 PSAP(195-273) dimer binds PE IEA Bos taurus 195410 R-CEL-1605624 https://reactome.org/PathwayBrowser/#/R-CEL-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Caenorhabditis elegans 195410 R-CEL-1605632 https://reactome.org/PathwayBrowser/#/R-CEL-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Caenorhabditis elegans 195410 R-CEL-1605736 https://reactome.org/PathwayBrowser/#/R-CEL-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Caenorhabditis elegans 195410 R-CEL-1606312 https://reactome.org/PathwayBrowser/#/R-CEL-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Caenorhabditis elegans 195410 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 195410 R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 195410 R-CEL-9842115 https://reactome.org/PathwayBrowser/#/R-CEL-9842115 PSAP(195-273) dimer binds PE IEA Caenorhabditis elegans 195410 R-CFA-1605624 https://reactome.org/PathwayBrowser/#/R-CFA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Canis familiaris 195410 R-CFA-1605632 https://reactome.org/PathwayBrowser/#/R-CFA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Canis familiaris 195410 R-CFA-1605724 https://reactome.org/PathwayBrowser/#/R-CFA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Canis familiaris 195410 R-CFA-1605736 https://reactome.org/PathwayBrowser/#/R-CFA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Canis familiaris 195410 R-CFA-1606312 https://reactome.org/PathwayBrowser/#/R-CFA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Canis familiaris 195410 R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 195410 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 195410 R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 195410 R-CFA-9842115 https://reactome.org/PathwayBrowser/#/R-CFA-9842115 PSAP(195-273) dimer binds PE IEA Canis familiaris 195410 R-DDI-1605624 https://reactome.org/PathwayBrowser/#/R-DDI-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Dictyostelium discoideum 195410 R-DDI-1605632 https://reactome.org/PathwayBrowser/#/R-DDI-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Dictyostelium discoideum 195410 R-DDI-1605736 https://reactome.org/PathwayBrowser/#/R-DDI-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Dictyostelium discoideum 195410 R-DDI-1606312 https://reactome.org/PathwayBrowser/#/R-DDI-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Dictyostelium discoideum 195410 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 195410 R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 195410 R-DDI-9842115 https://reactome.org/PathwayBrowser/#/R-DDI-9842115 PSAP(195-273) dimer binds PE IEA Dictyostelium discoideum 195410 R-DME-1605624 https://reactome.org/PathwayBrowser/#/R-DME-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Drosophila melanogaster 195410 R-DME-1605632 https://reactome.org/PathwayBrowser/#/R-DME-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Drosophila melanogaster 195410 R-DME-1606312 https://reactome.org/PathwayBrowser/#/R-DME-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Drosophila melanogaster 195410 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 195410 R-DME-9842115 https://reactome.org/PathwayBrowser/#/R-DME-9842115 PSAP(195-273) dimer binds PE IEA Drosophila melanogaster 195410 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus 195410 R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus 195410 R-GGA-1605724 https://reactome.org/PathwayBrowser/#/R-GGA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Gallus gallus 195410 R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus 195410 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus 195410 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 195410 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 195410 R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 195410 R-GGA-9842115 https://reactome.org/PathwayBrowser/#/R-GGA-9842115 PSAP(195-273) dimer binds PE IEA Gallus gallus 195410 R-HSA-1605624 https://reactome.org/PathwayBrowser/#/R-HSA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 TAS Homo sapiens 195410 R-HSA-1605632 https://reactome.org/PathwayBrowser/#/R-HSA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE TAS Homo sapiens 195410 R-HSA-1605724 https://reactome.org/PathwayBrowser/#/R-HSA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE TAS Homo sapiens 195410 R-HSA-1605736 https://reactome.org/PathwayBrowser/#/R-HSA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE TAS Homo sapiens 195410 R-HSA-1606312 https://reactome.org/PathwayBrowser/#/R-HSA-1606312 GLB1 hydrolyzes SapB/C:LacCer TAS Homo sapiens 195410 R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 195410 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 195410 R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 195410 R-HSA-9842115 https://reactome.org/PathwayBrowser/#/R-HSA-9842115 PSAP(195-273) dimer binds PE TAS Homo sapiens 195410 R-MMU-1605624 https://reactome.org/PathwayBrowser/#/R-MMU-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Mus musculus 195410 R-MMU-1605632 https://reactome.org/PathwayBrowser/#/R-MMU-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Mus musculus 195410 R-MMU-1605724 https://reactome.org/PathwayBrowser/#/R-MMU-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Mus musculus 195410 R-MMU-1605736 https://reactome.org/PathwayBrowser/#/R-MMU-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Mus musculus 195410 R-MMU-1606312 https://reactome.org/PathwayBrowser/#/R-MMU-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Mus musculus 195410 R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 195410 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 195410 R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 195410 R-MMU-9842115 https://reactome.org/PathwayBrowser/#/R-MMU-9842115 PSAP(195-273) dimer binds PE IEA Mus musculus 195410 R-RNO-1605624 https://reactome.org/PathwayBrowser/#/R-RNO-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Rattus norvegicus 195410 R-RNO-1605632 https://reactome.org/PathwayBrowser/#/R-RNO-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Rattus norvegicus 195410 R-RNO-1605724 https://reactome.org/PathwayBrowser/#/R-RNO-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Rattus norvegicus 195410 R-RNO-1605736 https://reactome.org/PathwayBrowser/#/R-RNO-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Rattus norvegicus 195410 R-RNO-1606312 https://reactome.org/PathwayBrowser/#/R-RNO-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Rattus norvegicus 195410 R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 195410 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 195410 R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 195410 R-RNO-9842115 https://reactome.org/PathwayBrowser/#/R-RNO-9842115 PSAP(195-273) dimer binds PE IEA Rattus norvegicus 195410 R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa 195410 R-SSC-1605632 https://reactome.org/PathwayBrowser/#/R-SSC-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Sus scrofa 195410 R-SSC-1605724 https://reactome.org/PathwayBrowser/#/R-SSC-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Sus scrofa 195410 R-SSC-1605736 https://reactome.org/PathwayBrowser/#/R-SSC-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Sus scrofa 195410 R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa 195410 R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 195410 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 195410 R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 195410 R-SSC-9842115 https://reactome.org/PathwayBrowser/#/R-SSC-9842115 PSAP(195-273) dimer binds PE IEA Sus scrofa 195411 R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus 195411 R-BTA-1605632 https://reactome.org/PathwayBrowser/#/R-BTA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Bos taurus 195411 R-BTA-1605724 https://reactome.org/PathwayBrowser/#/R-BTA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Bos taurus 195411 R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus 195411 R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus 195411 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 195411 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 195411 R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 195411 R-BTA-9842115 https://reactome.org/PathwayBrowser/#/R-BTA-9842115 PSAP(195-273) dimer binds PE IEA Bos taurus 195411 R-CEL-1605624 https://reactome.org/PathwayBrowser/#/R-CEL-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Caenorhabditis elegans 195411 R-CEL-1605632 https://reactome.org/PathwayBrowser/#/R-CEL-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Caenorhabditis elegans 195411 R-CEL-1605736 https://reactome.org/PathwayBrowser/#/R-CEL-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Caenorhabditis elegans 195411 R-CEL-1606312 https://reactome.org/PathwayBrowser/#/R-CEL-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Caenorhabditis elegans 195411 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 195411 R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 195411 R-CEL-9842115 https://reactome.org/PathwayBrowser/#/R-CEL-9842115 PSAP(195-273) dimer binds PE IEA Caenorhabditis elegans 195411 R-CFA-1605624 https://reactome.org/PathwayBrowser/#/R-CFA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Canis familiaris 195411 R-CFA-1605632 https://reactome.org/PathwayBrowser/#/R-CFA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Canis familiaris 195411 R-CFA-1605724 https://reactome.org/PathwayBrowser/#/R-CFA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Canis familiaris 195411 R-CFA-1605736 https://reactome.org/PathwayBrowser/#/R-CFA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Canis familiaris 195411 R-CFA-1606312 https://reactome.org/PathwayBrowser/#/R-CFA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Canis familiaris 195411 R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 195411 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 195411 R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 195411 R-CFA-9842115 https://reactome.org/PathwayBrowser/#/R-CFA-9842115 PSAP(195-273) dimer binds PE IEA Canis familiaris 195411 R-DDI-1605624 https://reactome.org/PathwayBrowser/#/R-DDI-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Dictyostelium discoideum 195411 R-DDI-1605632 https://reactome.org/PathwayBrowser/#/R-DDI-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Dictyostelium discoideum 195411 R-DDI-1605736 https://reactome.org/PathwayBrowser/#/R-DDI-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Dictyostelium discoideum 195411 R-DDI-1606312 https://reactome.org/PathwayBrowser/#/R-DDI-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Dictyostelium discoideum 195411 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 195411 R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 195411 R-DDI-9842115 https://reactome.org/PathwayBrowser/#/R-DDI-9842115 PSAP(195-273) dimer binds PE IEA Dictyostelium discoideum 195411 R-DME-1605624 https://reactome.org/PathwayBrowser/#/R-DME-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Drosophila melanogaster 195411 R-DME-1605632 https://reactome.org/PathwayBrowser/#/R-DME-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Drosophila melanogaster 195411 R-DME-1606312 https://reactome.org/PathwayBrowser/#/R-DME-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Drosophila melanogaster 195411 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 195411 R-DME-9842115 https://reactome.org/PathwayBrowser/#/R-DME-9842115 PSAP(195-273) dimer binds PE IEA Drosophila melanogaster 195411 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus 195411 R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus 195411 R-GGA-1605724 https://reactome.org/PathwayBrowser/#/R-GGA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Gallus gallus 195411 R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus 195411 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus 195411 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 195411 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 195411 R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 195411 R-GGA-9842115 https://reactome.org/PathwayBrowser/#/R-GGA-9842115 PSAP(195-273) dimer binds PE IEA Gallus gallus 195411 R-HSA-1605624 https://reactome.org/PathwayBrowser/#/R-HSA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 TAS Homo sapiens 195411 R-HSA-1605632 https://reactome.org/PathwayBrowser/#/R-HSA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE TAS Homo sapiens 195411 R-HSA-1605724 https://reactome.org/PathwayBrowser/#/R-HSA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE TAS Homo sapiens 195411 R-HSA-1605736 https://reactome.org/PathwayBrowser/#/R-HSA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE TAS Homo sapiens 195411 R-HSA-1606312 https://reactome.org/PathwayBrowser/#/R-HSA-1606312 GLB1 hydrolyzes SapB/C:LacCer TAS Homo sapiens 195411 R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 195411 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 195411 R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 195411 R-HSA-9842115 https://reactome.org/PathwayBrowser/#/R-HSA-9842115 PSAP(195-273) dimer binds PE TAS Homo sapiens 195411 R-MMU-1605624 https://reactome.org/PathwayBrowser/#/R-MMU-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Mus musculus 195411 R-MMU-1605632 https://reactome.org/PathwayBrowser/#/R-MMU-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Mus musculus 195411 R-MMU-1605724 https://reactome.org/PathwayBrowser/#/R-MMU-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Mus musculus 195411 R-MMU-1605736 https://reactome.org/PathwayBrowser/#/R-MMU-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Mus musculus 195411 R-MMU-1606312 https://reactome.org/PathwayBrowser/#/R-MMU-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Mus musculus 195411 R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 195411 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 195411 R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 195411 R-MMU-9842115 https://reactome.org/PathwayBrowser/#/R-MMU-9842115 PSAP(195-273) dimer binds PE IEA Mus musculus 195411 R-RNO-1605624 https://reactome.org/PathwayBrowser/#/R-RNO-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Rattus norvegicus 195411 R-RNO-1605632 https://reactome.org/PathwayBrowser/#/R-RNO-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Rattus norvegicus 195411 R-RNO-1605724 https://reactome.org/PathwayBrowser/#/R-RNO-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Rattus norvegicus 195411 R-RNO-1605736 https://reactome.org/PathwayBrowser/#/R-RNO-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Rattus norvegicus 195411 R-RNO-1606312 https://reactome.org/PathwayBrowser/#/R-RNO-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Rattus norvegicus 195411 R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 195411 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 195411 R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 195411 R-RNO-9842115 https://reactome.org/PathwayBrowser/#/R-RNO-9842115 PSAP(195-273) dimer binds PE IEA Rattus norvegicus 195411 R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa 195411 R-SSC-1605632 https://reactome.org/PathwayBrowser/#/R-SSC-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Sus scrofa 195411 R-SSC-1605724 https://reactome.org/PathwayBrowser/#/R-SSC-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Sus scrofa 195411 R-SSC-1605736 https://reactome.org/PathwayBrowser/#/R-SSC-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Sus scrofa 195411 R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa 195411 R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 195411 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 195411 R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 195411 R-SSC-9842115 https://reactome.org/PathwayBrowser/#/R-SSC-9842115 PSAP(195-273) dimer binds PE IEA Sus scrofa 195476 R-BTA-1605717 https://reactome.org/PathwayBrowser/#/R-BTA-1605717 GM2A binds and mobilizes ligands IEA Bos taurus 195476 R-BTA-9840795 https://reactome.org/PathwayBrowser/#/R-BTA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Bos taurus 195476 R-BTA-9840833 https://reactome.org/PathwayBrowser/#/R-BTA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Bos taurus 195476 R-CEL-1605717 https://reactome.org/PathwayBrowser/#/R-CEL-1605717 GM2A binds and mobilizes ligands IEA Caenorhabditis elegans 195476 R-CEL-9840795 https://reactome.org/PathwayBrowser/#/R-CEL-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Caenorhabditis elegans 195476 R-CEL-9840833 https://reactome.org/PathwayBrowser/#/R-CEL-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Caenorhabditis elegans 195476 R-CFA-1605717 https://reactome.org/PathwayBrowser/#/R-CFA-1605717 GM2A binds and mobilizes ligands IEA Canis familiaris 195476 R-CFA-9840795 https://reactome.org/PathwayBrowser/#/R-CFA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Canis familiaris 195476 R-CFA-9840833 https://reactome.org/PathwayBrowser/#/R-CFA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Canis familiaris 195476 R-HSA-1605717 https://reactome.org/PathwayBrowser/#/R-HSA-1605717 GM2A binds and mobilizes ligands TAS Homo sapiens 195476 R-HSA-9840795 https://reactome.org/PathwayBrowser/#/R-HSA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 TAS Homo sapiens 195476 R-HSA-9840833 https://reactome.org/PathwayBrowser/#/R-HSA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer TAS Homo sapiens 195476 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 195476 R-MMU-1605717 https://reactome.org/PathwayBrowser/#/R-MMU-1605717 GM2A binds and mobilizes ligands IEA Mus musculus 195476 R-MMU-9840795 https://reactome.org/PathwayBrowser/#/R-MMU-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Mus musculus 195476 R-MMU-9840833 https://reactome.org/PathwayBrowser/#/R-MMU-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Mus musculus 195476 R-RNO-1605717 https://reactome.org/PathwayBrowser/#/R-RNO-1605717 GM2A binds and mobilizes ligands IEA Rattus norvegicus 195476 R-RNO-9840795 https://reactome.org/PathwayBrowser/#/R-RNO-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Rattus norvegicus 195476 R-RNO-9840833 https://reactome.org/PathwayBrowser/#/R-RNO-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Rattus norvegicus 195476 R-SSC-1605717 https://reactome.org/PathwayBrowser/#/R-SSC-1605717 GM2A binds and mobilizes ligands IEA Sus scrofa 195476 R-SSC-9840795 https://reactome.org/PathwayBrowser/#/R-SSC-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Sus scrofa 195476 R-SSC-9840833 https://reactome.org/PathwayBrowser/#/R-SSC-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Sus scrofa 195476 R-XTR-1605717 https://reactome.org/PathwayBrowser/#/R-XTR-1605717 GM2A binds and mobilizes ligands IEA Xenopus tropicalis 195476 R-XTR-9840795 https://reactome.org/PathwayBrowser/#/R-XTR-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Xenopus tropicalis 195476 R-XTR-9840833 https://reactome.org/PathwayBrowser/#/R-XTR-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Xenopus tropicalis 195546 R-BTA-1605723 https://reactome.org/PathwayBrowser/#/R-BTA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Bos taurus 195546 R-BTA-1605724 https://reactome.org/PathwayBrowser/#/R-BTA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Bos taurus 195546 R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus 195546 R-BTA-1605768 https://reactome.org/PathwayBrowser/#/R-BTA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Bos taurus 195546 R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus 195546 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 195546 R-BTA-9840833 https://reactome.org/PathwayBrowser/#/R-BTA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Bos taurus 195546 R-BTA-9840949 https://reactome.org/PathwayBrowser/#/R-BTA-9840949 ARSA removes sulfate from SM3 IEA Bos taurus 195546 R-CEL-1605736 https://reactome.org/PathwayBrowser/#/R-CEL-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Caenorhabditis elegans 195546 R-CEL-1606312 https://reactome.org/PathwayBrowser/#/R-CEL-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Caenorhabditis elegans 195546 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 195546 R-CEL-9840833 https://reactome.org/PathwayBrowser/#/R-CEL-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Caenorhabditis elegans 195546 R-CFA-1605723 https://reactome.org/PathwayBrowser/#/R-CFA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Canis familiaris 195546 R-CFA-1605724 https://reactome.org/PathwayBrowser/#/R-CFA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Canis familiaris 195546 R-CFA-1605736 https://reactome.org/PathwayBrowser/#/R-CFA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Canis familiaris 195546 R-CFA-1605768 https://reactome.org/PathwayBrowser/#/R-CFA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Canis familiaris 195546 R-CFA-1606312 https://reactome.org/PathwayBrowser/#/R-CFA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Canis familiaris 195546 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 195546 R-CFA-9840833 https://reactome.org/PathwayBrowser/#/R-CFA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Canis familiaris 195546 R-CFA-9840949 https://reactome.org/PathwayBrowser/#/R-CFA-9840949 ARSA removes sulfate from SM3 IEA Canis familiaris 195546 R-DDI-1605736 https://reactome.org/PathwayBrowser/#/R-DDI-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Dictyostelium discoideum 195546 R-DDI-1606312 https://reactome.org/PathwayBrowser/#/R-DDI-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Dictyostelium discoideum 195546 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 195546 R-DME-1606312 https://reactome.org/PathwayBrowser/#/R-DME-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Drosophila melanogaster 195546 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 195546 R-DRE-1605723 https://reactome.org/PathwayBrowser/#/R-DRE-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Danio rerio 195546 R-DRE-1605768 https://reactome.org/PathwayBrowser/#/R-DRE-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Danio rerio 195546 R-GGA-1605723 https://reactome.org/PathwayBrowser/#/R-GGA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Gallus gallus 195546 R-GGA-1605724 https://reactome.org/PathwayBrowser/#/R-GGA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Gallus gallus 195546 R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus 195546 R-GGA-1605768 https://reactome.org/PathwayBrowser/#/R-GGA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Gallus gallus 195546 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus 195546 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 195546 R-GGA-9840949 https://reactome.org/PathwayBrowser/#/R-GGA-9840949 ARSA removes sulfate from SM3 IEA Gallus gallus 195546 R-HSA-1605723 https://reactome.org/PathwayBrowser/#/R-HSA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) TAS Homo sapiens 195546 R-HSA-1605724 https://reactome.org/PathwayBrowser/#/R-HSA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE TAS Homo sapiens 195546 R-HSA-1605736 https://reactome.org/PathwayBrowser/#/R-HSA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE TAS Homo sapiens 195546 R-HSA-1605768 https://reactome.org/PathwayBrowser/#/R-HSA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) TAS Homo sapiens 195546 R-HSA-1606312 https://reactome.org/PathwayBrowser/#/R-HSA-1606312 GLB1 hydrolyzes SapB/C:LacCer TAS Homo sapiens 195546 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 195546 R-HSA-9840833 https://reactome.org/PathwayBrowser/#/R-HSA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer TAS Homo sapiens 195546 R-HSA-9840949 https://reactome.org/PathwayBrowser/#/R-HSA-9840949 ARSA removes sulfate from SM3 TAS Homo sapiens 195546 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 195546 R-MMU-1605723 https://reactome.org/PathwayBrowser/#/R-MMU-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Mus musculus 195546 R-MMU-1605724 https://reactome.org/PathwayBrowser/#/R-MMU-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Mus musculus 195546 R-MMU-1605736 https://reactome.org/PathwayBrowser/#/R-MMU-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Mus musculus 195546 R-MMU-1605768 https://reactome.org/PathwayBrowser/#/R-MMU-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Mus musculus 195546 R-MMU-1606312 https://reactome.org/PathwayBrowser/#/R-MMU-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Mus musculus 195546 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 195546 R-MMU-9840833 https://reactome.org/PathwayBrowser/#/R-MMU-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Mus musculus 195546 R-MMU-9840949 https://reactome.org/PathwayBrowser/#/R-MMU-9840949 ARSA removes sulfate from SM3 IEA Mus musculus 195546 R-RNO-1605723 https://reactome.org/PathwayBrowser/#/R-RNO-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Rattus norvegicus 195546 R-RNO-1605724 https://reactome.org/PathwayBrowser/#/R-RNO-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Rattus norvegicus 195546 R-RNO-1605736 https://reactome.org/PathwayBrowser/#/R-RNO-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Rattus norvegicus 195546 R-RNO-1605768 https://reactome.org/PathwayBrowser/#/R-RNO-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Rattus norvegicus 195546 R-RNO-1606312 https://reactome.org/PathwayBrowser/#/R-RNO-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Rattus norvegicus 195546 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 195546 R-RNO-9840833 https://reactome.org/PathwayBrowser/#/R-RNO-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Rattus norvegicus 195546 R-RNO-9840949 https://reactome.org/PathwayBrowser/#/R-RNO-9840949 ARSA removes sulfate from SM3 IEA Rattus norvegicus 195546 R-SPO-9840949 https://reactome.org/PathwayBrowser/#/R-SPO-9840949 ARSA removes sulfate from SM3 IEA Schizosaccharomyces pombe 195546 R-SSC-1605723 https://reactome.org/PathwayBrowser/#/R-SSC-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Sus scrofa 195546 R-SSC-1605724 https://reactome.org/PathwayBrowser/#/R-SSC-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Sus scrofa 195546 R-SSC-1605736 https://reactome.org/PathwayBrowser/#/R-SSC-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Sus scrofa 195546 R-SSC-1605768 https://reactome.org/PathwayBrowser/#/R-SSC-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Sus scrofa 195546 R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa 195546 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 195546 R-SSC-9840833 https://reactome.org/PathwayBrowser/#/R-SSC-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Sus scrofa 195546 R-SSC-9840949 https://reactome.org/PathwayBrowser/#/R-SSC-9840949 ARSA removes sulfate from SM3 IEA Sus scrofa 195546 R-XTR-1605723 https://reactome.org/PathwayBrowser/#/R-XTR-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Xenopus tropicalis 195546 R-XTR-1605768 https://reactome.org/PathwayBrowser/#/R-XTR-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Xenopus tropicalis 195546 R-XTR-9840833 https://reactome.org/PathwayBrowser/#/R-XTR-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Xenopus tropicalis 195546 R-XTR-9840949 https://reactome.org/PathwayBrowser/#/R-XTR-9840949 ARSA removes sulfate from SM3 IEA Xenopus tropicalis 195634 R-BTA-428259 https://reactome.org/PathwayBrowser/#/R-BTA-428259 DEGS1 dehydrogenates dihydroceramide IEA Bos taurus 195634 R-CEL-428259 https://reactome.org/PathwayBrowser/#/R-CEL-428259 DEGS1 dehydrogenates dihydroceramide IEA Caenorhabditis elegans 195634 R-CFA-428259 https://reactome.org/PathwayBrowser/#/R-CFA-428259 DEGS1 dehydrogenates dihydroceramide IEA Canis familiaris 195634 R-DDI-428259 https://reactome.org/PathwayBrowser/#/R-DDI-428259 DEGS1 dehydrogenates dihydroceramide IEA Dictyostelium discoideum 195634 R-DME-428259 https://reactome.org/PathwayBrowser/#/R-DME-428259 DEGS1 dehydrogenates dihydroceramide IEA Drosophila melanogaster 195634 R-DRE-428259 https://reactome.org/PathwayBrowser/#/R-DRE-428259 DEGS1 dehydrogenates dihydroceramide IEA Danio rerio 195634 R-GGA-428259 https://reactome.org/PathwayBrowser/#/R-GGA-428259 DEGS1 dehydrogenates dihydroceramide IEA Gallus gallus 195634 R-HSA-428259 https://reactome.org/PathwayBrowser/#/R-HSA-428259 DEGS1 dehydrogenates dihydroceramide TAS Homo sapiens 195634 R-MMU-428259 https://reactome.org/PathwayBrowser/#/R-MMU-428259 DEGS1 dehydrogenates dihydroceramide IEA Mus musculus 195634 R-RNO-428259 https://reactome.org/PathwayBrowser/#/R-RNO-428259 DEGS1 dehydrogenates dihydroceramide IEA Rattus norvegicus 195634 R-SPO-428259 https://reactome.org/PathwayBrowser/#/R-SPO-428259 DEGS1 dehydrogenates dihydroceramide IEA Schizosaccharomyces pombe 195634 R-SSC-428259 https://reactome.org/PathwayBrowser/#/R-SSC-428259 DEGS1 dehydrogenates dihydroceramide IEA Sus scrofa 195634 R-XTR-428259 https://reactome.org/PathwayBrowser/#/R-XTR-428259 DEGS1 dehydrogenates dihydroceramide IEA Xenopus tropicalis 196991 R-BTA-5692283 https://reactome.org/PathwayBrowser/#/R-BTA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Bos taurus 196991 R-CEL-5692283 https://reactome.org/PathwayBrowser/#/R-CEL-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Caenorhabditis elegans 196991 R-CFA-5692283 https://reactome.org/PathwayBrowser/#/R-CFA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Canis familiaris 196991 R-DDI-5692283 https://reactome.org/PathwayBrowser/#/R-DDI-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Dictyostelium discoideum 196991 R-DME-5692283 https://reactome.org/PathwayBrowser/#/R-DME-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Drosophila melanogaster 196991 R-DRE-5692283 https://reactome.org/PathwayBrowser/#/R-DRE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Danio rerio 196991 R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus 196991 R-HSA-5692283 https://reactome.org/PathwayBrowser/#/R-HSA-5692283 ALD3A1 oxidises 4HPCP to CXPA TAS Homo sapiens 196991 R-MMU-5692283 https://reactome.org/PathwayBrowser/#/R-MMU-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Mus musculus 196991 R-RNO-5692283 https://reactome.org/PathwayBrowser/#/R-RNO-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Rattus norvegicus 196991 R-SCE-5692283 https://reactome.org/PathwayBrowser/#/R-SCE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Saccharomyces cerevisiae 196991 R-SSC-5692283 https://reactome.org/PathwayBrowser/#/R-SSC-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Sus scrofa 20067 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 20067 R-BTA-444661 https://reactome.org/PathwayBrowser/#/R-BTA-444661 HCAR2 binds HCAR2 ligands IEA Bos taurus 20067 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 20067 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 20067 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 20067 R-CFA-444661 https://reactome.org/PathwayBrowser/#/R-CFA-444661 HCAR2 binds HCAR2 ligands IEA Canis familiaris 20067 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 20067 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 20067 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 20067 R-DRE-444661 https://reactome.org/PathwayBrowser/#/R-DRE-444661 HCAR2 binds HCAR2 ligands IEA Danio rerio 20067 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 20067 R-HSA-444661 https://reactome.org/PathwayBrowser/#/R-HSA-444661 HCAR2 binds HCAR2 ligands TAS Homo sapiens 20067 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 20067 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 20067 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 20067 R-MMU-444661 https://reactome.org/PathwayBrowser/#/R-MMU-444661 HCAR2 binds HCAR2 ligands IEA Mus musculus 20067 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 20067 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 20067 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 20067 R-RNO-444661 https://reactome.org/PathwayBrowser/#/R-RNO-444661 HCAR2 binds HCAR2 ligands IEA Rattus norvegicus 20067 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 20067 R-SSC-444661 https://reactome.org/PathwayBrowser/#/R-SSC-444661 HCAR2 binds HCAR2 ligands IEA Sus scrofa 20067 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 20067 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 202940 R-BTA-2162066 https://reactome.org/PathwayBrowser/#/R-BTA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Bos taurus 202940 R-CEL-2162066 https://reactome.org/PathwayBrowser/#/R-CEL-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Caenorhabditis elegans 202940 R-CFA-2162066 https://reactome.org/PathwayBrowser/#/R-CFA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Canis familiaris 202940 R-DDI-2162066 https://reactome.org/PathwayBrowser/#/R-DDI-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Dictyostelium discoideum 202940 R-DME-2162066 https://reactome.org/PathwayBrowser/#/R-DME-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Drosophila melanogaster 202940 R-GGA-2162066 https://reactome.org/PathwayBrowser/#/R-GGA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Gallus gallus 202940 R-HSA-2162066 https://reactome.org/PathwayBrowser/#/R-HSA-2162066 carbovir + IMP => carbovir monophosphate + inosine TAS Homo sapiens 202940 R-MMU-2162066 https://reactome.org/PathwayBrowser/#/R-MMU-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Mus musculus 202940 R-RNO-2162066 https://reactome.org/PathwayBrowser/#/R-RNO-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Rattus norvegicus 202940 R-SSC-2162066 https://reactome.org/PathwayBrowser/#/R-SSC-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Sus scrofa 202940 R-XTR-2162066 https://reactome.org/PathwayBrowser/#/R-XTR-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Xenopus tropicalis 203600 R-BTA-1112666 https://reactome.org/PathwayBrowser/#/R-BTA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Bos taurus 203600 R-BTA-111879 https://reactome.org/PathwayBrowser/#/R-BTA-111879 PIP2 hydrolysis IEA Bos taurus 203600 R-BTA-114688 https://reactome.org/PathwayBrowser/#/R-BTA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Bos taurus 203600 R-BTA-114689 https://reactome.org/PathwayBrowser/#/R-BTA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Bos taurus 203600 R-BTA-1168376 https://reactome.org/PathwayBrowser/#/R-BTA-1168376 STIM1 oligomerizes IEA Bos taurus 203600 R-BTA-139854 https://reactome.org/PathwayBrowser/#/R-BTA-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Bos taurus 203600 R-BTA-139941 https://reactome.org/PathwayBrowser/#/R-BTA-139941 Binding of IP3 to IP3 receptor IEA Bos taurus 203600 R-BTA-1855153 https://reactome.org/PathwayBrowser/#/R-BTA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Bos taurus 203600 R-BTA-1855174 https://reactome.org/PathwayBrowser/#/R-BTA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Bos taurus 203600 R-BTA-1855177 https://reactome.org/PathwayBrowser/#/R-BTA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Bos taurus 203600 R-BTA-1855200 https://reactome.org/PathwayBrowser/#/R-BTA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Bos taurus 203600 R-BTA-1855205 https://reactome.org/PathwayBrowser/#/R-BTA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Bos taurus 203600 R-BTA-1855214 https://reactome.org/PathwayBrowser/#/R-BTA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Bos taurus 203600 R-BTA-1855221 https://reactome.org/PathwayBrowser/#/R-BTA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Bos taurus 203600 R-BTA-1855222 https://reactome.org/PathwayBrowser/#/R-BTA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Bos taurus 203600 R-BTA-1855233 https://reactome.org/PathwayBrowser/#/R-BTA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Bos taurus 203600 R-BTA-202407 https://reactome.org/PathwayBrowser/#/R-BTA-202407 PLC-gamma1 hydrolyses PIP2 IEA Bos taurus 203600 R-BTA-2730847 https://reactome.org/PathwayBrowser/#/R-BTA-2730847 Hydrolysis of PIP2 by PLCG IEA Bos taurus 203600 R-BTA-381644 https://reactome.org/PathwayBrowser/#/R-BTA-381644 ER calcium channels open in response to activated PKA IEA Bos taurus 203600 R-BTA-398193 https://reactome.org/PathwayBrowser/#/R-BTA-398193 PLC beta-mediated PIP2 hydrolysis IEA Bos taurus 203600 R-BTA-399998 https://reactome.org/PathwayBrowser/#/R-BTA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Bos taurus 203600 R-BTA-5226904 https://reactome.org/PathwayBrowser/#/R-BTA-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Bos taurus 203600 R-BTA-5607735 https://reactome.org/PathwayBrowser/#/R-BTA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Bos taurus 203600 R-BTA-9717214 https://reactome.org/PathwayBrowser/#/R-BTA-9717214 I(1,4,5)P3 binds ITPR3 tetramer IEA Bos taurus 203600 R-BTA-9717215 https://reactome.org/PathwayBrowser/#/R-BTA-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Bos taurus 203600 R-CEL-111879 https://reactome.org/PathwayBrowser/#/R-CEL-111879 PIP2 hydrolysis IEA Caenorhabditis elegans 203600 R-CEL-114688 https://reactome.org/PathwayBrowser/#/R-CEL-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Caenorhabditis elegans 203600 R-CEL-1168376 https://reactome.org/PathwayBrowser/#/R-CEL-1168376 STIM1 oligomerizes IEA Caenorhabditis elegans 203600 R-CEL-139854 https://reactome.org/PathwayBrowser/#/R-CEL-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Caenorhabditis elegans 203600 R-CEL-139941 https://reactome.org/PathwayBrowser/#/R-CEL-139941 Binding of IP3 to IP3 receptor IEA Caenorhabditis elegans 203600 R-CEL-1855153 https://reactome.org/PathwayBrowser/#/R-CEL-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Caenorhabditis elegans 203600 R-CEL-1855174 https://reactome.org/PathwayBrowser/#/R-CEL-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Caenorhabditis elegans 203600 R-CEL-1855177 https://reactome.org/PathwayBrowser/#/R-CEL-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Caenorhabditis elegans 203600 R-CEL-1855205 https://reactome.org/PathwayBrowser/#/R-CEL-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Caenorhabditis elegans 203600 R-CEL-1855214 https://reactome.org/PathwayBrowser/#/R-CEL-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Caenorhabditis elegans 203600 R-CEL-1855221 https://reactome.org/PathwayBrowser/#/R-CEL-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Caenorhabditis elegans 203600 R-CEL-1855222 https://reactome.org/PathwayBrowser/#/R-CEL-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Caenorhabditis elegans 203600 R-CEL-1855233 https://reactome.org/PathwayBrowser/#/R-CEL-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Caenorhabditis elegans 203600 R-CEL-381644 https://reactome.org/PathwayBrowser/#/R-CEL-381644 ER calcium channels open in response to activated PKA IEA Caenorhabditis elegans 203600 R-CEL-9717214 https://reactome.org/PathwayBrowser/#/R-CEL-9717214 I(1,4,5)P3 binds ITPR3 tetramer IEA Caenorhabditis elegans 203600 R-CEL-9717215 https://reactome.org/PathwayBrowser/#/R-CEL-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Caenorhabditis elegans 203600 R-CFA-1112666 https://reactome.org/PathwayBrowser/#/R-CFA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Canis familiaris 203600 R-CFA-111879 https://reactome.org/PathwayBrowser/#/R-CFA-111879 PIP2 hydrolysis IEA Canis familiaris 203600 R-CFA-114688 https://reactome.org/PathwayBrowser/#/R-CFA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Canis familiaris 203600 R-CFA-114689 https://reactome.org/PathwayBrowser/#/R-CFA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Canis familiaris 203600 R-CFA-1168376 https://reactome.org/PathwayBrowser/#/R-CFA-1168376 STIM1 oligomerizes IEA Canis familiaris 203600 R-CFA-139854 https://reactome.org/PathwayBrowser/#/R-CFA-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Canis familiaris 203600 R-CFA-139941 https://reactome.org/PathwayBrowser/#/R-CFA-139941 Binding of IP3 to IP3 receptor IEA Canis familiaris 203600 R-CFA-1855153 https://reactome.org/PathwayBrowser/#/R-CFA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Canis familiaris 203600 R-CFA-1855174 https://reactome.org/PathwayBrowser/#/R-CFA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Canis familiaris 203600 R-CFA-1855177 https://reactome.org/PathwayBrowser/#/R-CFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Canis familiaris 203600 R-CFA-1855200 https://reactome.org/PathwayBrowser/#/R-CFA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Canis familiaris 203600 R-CFA-1855205 https://reactome.org/PathwayBrowser/#/R-CFA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Canis familiaris 203600 R-CFA-1855214 https://reactome.org/PathwayBrowser/#/R-CFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Canis familiaris 203600 R-CFA-1855221 https://reactome.org/PathwayBrowser/#/R-CFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Canis familiaris 203600 R-CFA-1855222 https://reactome.org/PathwayBrowser/#/R-CFA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Canis familiaris 203600 R-CFA-1855233 https://reactome.org/PathwayBrowser/#/R-CFA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Canis familiaris 203600 R-CFA-202407 https://reactome.org/PathwayBrowser/#/R-CFA-202407 PLC-gamma1 hydrolyses PIP2 IEA Canis familiaris 203600 R-CFA-2730847 https://reactome.org/PathwayBrowser/#/R-CFA-2730847 Hydrolysis of PIP2 by PLCG IEA Canis familiaris 203600 R-CFA-381644 https://reactome.org/PathwayBrowser/#/R-CFA-381644 ER calcium channels open in response to activated PKA IEA Canis familiaris 203600 R-CFA-398193 https://reactome.org/PathwayBrowser/#/R-CFA-398193 PLC beta-mediated PIP2 hydrolysis IEA Canis familiaris 203600 R-CFA-399998 https://reactome.org/PathwayBrowser/#/R-CFA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Canis familiaris 203600 R-CFA-5226904 https://reactome.org/PathwayBrowser/#/R-CFA-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Canis familiaris 203600 R-CFA-5607735 https://reactome.org/PathwayBrowser/#/R-CFA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Canis familiaris 203600 R-CFA-9717214 https://reactome.org/PathwayBrowser/#/R-CFA-9717214 I(1,4,5)P3 binds ITPR3 tetramer IEA Canis familiaris 203600 R-CFA-9717215 https://reactome.org/PathwayBrowser/#/R-CFA-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Canis familiaris 203600 R-DDI-111879 https://reactome.org/PathwayBrowser/#/R-DDI-111879 PIP2 hydrolysis IEA Dictyostelium discoideum 203600 R-DDI-114688 https://reactome.org/PathwayBrowser/#/R-DDI-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Dictyostelium discoideum 203600 R-DDI-114689 https://reactome.org/PathwayBrowser/#/R-DDI-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Dictyostelium discoideum 203600 R-DDI-139854 https://reactome.org/PathwayBrowser/#/R-DDI-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Dictyostelium discoideum 203600 R-DDI-139941 https://reactome.org/PathwayBrowser/#/R-DDI-139941 Binding of IP3 to IP3 receptor IEA Dictyostelium discoideum 203600 R-DDI-1855153 https://reactome.org/PathwayBrowser/#/R-DDI-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Dictyostelium discoideum 203600 R-DDI-1855174 https://reactome.org/PathwayBrowser/#/R-DDI-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Dictyostelium discoideum 203600 R-DDI-1855177 https://reactome.org/PathwayBrowser/#/R-DDI-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Dictyostelium discoideum 203600 R-DDI-1855200 https://reactome.org/PathwayBrowser/#/R-DDI-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 203600 R-DDI-1855205 https://reactome.org/PathwayBrowser/#/R-DDI-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Dictyostelium discoideum 203600 R-DDI-1855214 https://reactome.org/PathwayBrowser/#/R-DDI-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Dictyostelium discoideum 203600 R-DDI-1855221 https://reactome.org/PathwayBrowser/#/R-DDI-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Dictyostelium discoideum 203600 R-DDI-1855222 https://reactome.org/PathwayBrowser/#/R-DDI-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Dictyostelium discoideum 203600 R-DDI-1855233 https://reactome.org/PathwayBrowser/#/R-DDI-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Dictyostelium discoideum 203600 R-DDI-202407 https://reactome.org/PathwayBrowser/#/R-DDI-202407 PLC-gamma1 hydrolyses PIP2 IEA Dictyostelium discoideum 203600 R-DDI-381644 https://reactome.org/PathwayBrowser/#/R-DDI-381644 ER calcium channels open in response to activated PKA IEA Dictyostelium discoideum 203600 R-DDI-399998 https://reactome.org/PathwayBrowser/#/R-DDI-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Dictyostelium discoideum 203600 R-DDI-5607735 https://reactome.org/PathwayBrowser/#/R-DDI-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Dictyostelium discoideum 203600 R-DDI-9717214 https://reactome.org/PathwayBrowser/#/R-DDI-9717214 I(1,4,5)P3 binds ITPR3 tetramer IEA Dictyostelium discoideum 203600 R-DDI-9717215 https://reactome.org/PathwayBrowser/#/R-DDI-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Dictyostelium discoideum 203600 R-DME-111879 https://reactome.org/PathwayBrowser/#/R-DME-111879 PIP2 hydrolysis IEA Drosophila melanogaster 203600 R-DME-114688 https://reactome.org/PathwayBrowser/#/R-DME-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Drosophila melanogaster 203600 R-DME-114689 https://reactome.org/PathwayBrowser/#/R-DME-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Drosophila melanogaster 203600 R-DME-1168376 https://reactome.org/PathwayBrowser/#/R-DME-1168376 STIM1 oligomerizes IEA Drosophila melanogaster 203600 R-DME-139854 https://reactome.org/PathwayBrowser/#/R-DME-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Drosophila melanogaster 203600 R-DME-139941 https://reactome.org/PathwayBrowser/#/R-DME-139941 Binding of IP3 to IP3 receptor IEA Drosophila melanogaster 203600 R-DME-1855153 https://reactome.org/PathwayBrowser/#/R-DME-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Drosophila melanogaster 203600 R-DME-1855174 https://reactome.org/PathwayBrowser/#/R-DME-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Drosophila melanogaster 203600 R-DME-1855177 https://reactome.org/PathwayBrowser/#/R-DME-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Drosophila melanogaster 203600 R-DME-1855205 https://reactome.org/PathwayBrowser/#/R-DME-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Drosophila melanogaster 203600 R-DME-1855214 https://reactome.org/PathwayBrowser/#/R-DME-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Drosophila melanogaster 203600 R-DME-1855221 https://reactome.org/PathwayBrowser/#/R-DME-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Drosophila melanogaster 203600 R-DME-1855222 https://reactome.org/PathwayBrowser/#/R-DME-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Drosophila melanogaster 203600 R-DME-1855233 https://reactome.org/PathwayBrowser/#/R-DME-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Drosophila melanogaster 203600 R-DME-202407 https://reactome.org/PathwayBrowser/#/R-DME-202407 PLC-gamma1 hydrolyses PIP2 IEA Drosophila melanogaster 203600 R-DME-2730847 https://reactome.org/PathwayBrowser/#/R-DME-2730847 Hydrolysis of PIP2 by PLCG IEA Drosophila melanogaster 203600 R-DME-381644 https://reactome.org/PathwayBrowser/#/R-DME-381644 ER calcium channels open in response to activated PKA IEA Drosophila melanogaster 203600 R-DME-398193 https://reactome.org/PathwayBrowser/#/R-DME-398193 PLC beta-mediated PIP2 hydrolysis IEA Drosophila melanogaster 203600 R-DME-399998 https://reactome.org/PathwayBrowser/#/R-DME-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Drosophila melanogaster 203600 R-DME-5226904 https://reactome.org/PathwayBrowser/#/R-DME-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Drosophila melanogaster 203600 R-DME-5607735 https://reactome.org/PathwayBrowser/#/R-DME-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Drosophila melanogaster 203600 R-DME-9717214 https://reactome.org/PathwayBrowser/#/R-DME-9717214 I(1,4,5)P3 binds ITPR3 tetramer IEA Drosophila melanogaster 203600 R-DME-9717215 https://reactome.org/PathwayBrowser/#/R-DME-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Drosophila melanogaster 203600 R-DRE-1855200 https://reactome.org/PathwayBrowser/#/R-DRE-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Danio rerio 203600 R-DRE-1855205 https://reactome.org/PathwayBrowser/#/R-DRE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Danio rerio 203600 R-DRE-1855221 https://reactome.org/PathwayBrowser/#/R-DRE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Danio rerio 203600 R-DRE-1855222 https://reactome.org/PathwayBrowser/#/R-DRE-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Danio rerio 203600 R-DRE-1855233 https://reactome.org/PathwayBrowser/#/R-DRE-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Danio rerio 203600 R-DRE-202407 https://reactome.org/PathwayBrowser/#/R-DRE-202407 PLC-gamma1 hydrolyses PIP2 IEA Danio rerio 203600 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus 203600 R-GGA-111879 https://reactome.org/PathwayBrowser/#/R-GGA-111879 PIP2 hydrolysis IEA Gallus gallus 203600 R-GGA-114688 https://reactome.org/PathwayBrowser/#/R-GGA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Gallus gallus 203600 R-GGA-114689 https://reactome.org/PathwayBrowser/#/R-GGA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Gallus gallus 203600 R-GGA-1168376 https://reactome.org/PathwayBrowser/#/R-GGA-1168376 STIM1 oligomerizes IEA Gallus gallus 203600 R-GGA-139854 https://reactome.org/PathwayBrowser/#/R-GGA-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Gallus gallus 203600 R-GGA-139941 https://reactome.org/PathwayBrowser/#/R-GGA-139941 Binding of IP3 to IP3 receptor IEA Gallus gallus 203600 R-GGA-1855153 https://reactome.org/PathwayBrowser/#/R-GGA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Gallus gallus 203600 R-GGA-1855174 https://reactome.org/PathwayBrowser/#/R-GGA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Gallus gallus 203600 R-GGA-1855177 https://reactome.org/PathwayBrowser/#/R-GGA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Gallus gallus 203600 R-GGA-1855200 https://reactome.org/PathwayBrowser/#/R-GGA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Gallus gallus 203600 R-GGA-1855205 https://reactome.org/PathwayBrowser/#/R-GGA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Gallus gallus 203600 R-GGA-1855214 https://reactome.org/PathwayBrowser/#/R-GGA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Gallus gallus 203600 R-GGA-1855221 https://reactome.org/PathwayBrowser/#/R-GGA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Gallus gallus 203600 R-GGA-1855222 https://reactome.org/PathwayBrowser/#/R-GGA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Gallus gallus 203600 R-GGA-1855233 https://reactome.org/PathwayBrowser/#/R-GGA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Gallus gallus 203600 R-GGA-202407 https://reactome.org/PathwayBrowser/#/R-GGA-202407 PLC-gamma1 hydrolyses PIP2 IEA Gallus gallus 203600 R-GGA-2730847 https://reactome.org/PathwayBrowser/#/R-GGA-2730847 Hydrolysis of PIP2 by PLCG IEA Gallus gallus 203600 R-GGA-381644 https://reactome.org/PathwayBrowser/#/R-GGA-381644 ER calcium channels open in response to activated PKA IEA Gallus gallus 203600 R-GGA-398193 https://reactome.org/PathwayBrowser/#/R-GGA-398193 PLC beta-mediated PIP2 hydrolysis IEA Gallus gallus 203600 R-GGA-399998 https://reactome.org/PathwayBrowser/#/R-GGA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Gallus gallus 203600 R-GGA-5226904 https://reactome.org/PathwayBrowser/#/R-GGA-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Gallus gallus 203600 R-GGA-5607735 https://reactome.org/PathwayBrowser/#/R-GGA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Gallus gallus 203600 R-HSA-1112666 https://reactome.org/PathwayBrowser/#/R-HSA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate TAS Homo sapiens 203600 R-HSA-111879 https://reactome.org/PathwayBrowser/#/R-HSA-111879 PIP2 hydrolysis TAS Homo sapiens 203600 R-HSA-114688 https://reactome.org/PathwayBrowser/#/R-HSA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 TAS Homo sapiens 203600 R-HSA-114689 https://reactome.org/PathwayBrowser/#/R-HSA-114689 PLC gamma 2-mediated PIP2 hydrolysis TAS Homo sapiens 203600 R-HSA-1168376 https://reactome.org/PathwayBrowser/#/R-HSA-1168376 STIM1 oligomerizes TAS Homo sapiens 203600 R-HSA-139854 https://reactome.org/PathwayBrowser/#/R-HSA-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol TAS Homo sapiens 203600 R-HSA-139941 https://reactome.org/PathwayBrowser/#/R-HSA-139941 Binding of IP3 to IP3 receptor TAS Homo sapiens 203600 R-HSA-167686 https://reactome.org/PathwayBrowser/#/R-HSA-167686 Active PLCG1 hydrolyses PIP2 IEA Homo sapiens 203600 R-HSA-169680 https://reactome.org/PathwayBrowser/#/R-HSA-169680 IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel IEA Homo sapiens 203600 R-HSA-169683 https://reactome.org/PathwayBrowser/#/R-HSA-169683 IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol IEA Homo sapiens 203600 R-HSA-1855153 https://reactome.org/PathwayBrowser/#/R-HSA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol TAS Homo sapiens 203600 R-HSA-1855174 https://reactome.org/PathwayBrowser/#/R-HSA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol TAS Homo sapiens 203600 R-HSA-1855177 https://reactome.org/PathwayBrowser/#/R-HSA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane TAS Homo sapiens 203600 R-HSA-1855190 https://reactome.org/PathwayBrowser/#/R-HSA-1855190 I(1,4,5)P3 transports from the cytosol to the nucleus TAS Homo sapiens 203600 R-HSA-1855200 https://reactome.org/PathwayBrowser/#/R-HSA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen TAS Homo sapiens 203600 R-HSA-1855205 https://reactome.org/PathwayBrowser/#/R-HSA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol TAS Homo sapiens 203600 R-HSA-1855214 https://reactome.org/PathwayBrowser/#/R-HSA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane TAS Homo sapiens 203600 R-HSA-1855217 https://reactome.org/PathwayBrowser/#/R-HSA-1855217 I(1,4,5)P3 transports from the ER lumen to the cytosol TAS Homo sapiens 203600 R-HSA-1855221 https://reactome.org/PathwayBrowser/#/R-HSA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane TAS Homo sapiens 203600 R-HSA-1855222 https://reactome.org/PathwayBrowser/#/R-HSA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane TAS Homo sapiens 203600 R-HSA-1855233 https://reactome.org/PathwayBrowser/#/R-HSA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus TAS Homo sapiens 203600 R-HSA-202407 https://reactome.org/PathwayBrowser/#/R-HSA-202407 PLC-gamma1 hydrolyses PIP2 TAS Homo sapiens 203600 R-HSA-2730847 https://reactome.org/PathwayBrowser/#/R-HSA-2730847 Hydrolysis of PIP2 by PLCG TAS Homo sapiens 203600 R-HSA-381644 https://reactome.org/PathwayBrowser/#/R-HSA-381644 ER calcium channels open in response to activated PKA TAS Homo sapiens 203600 R-HSA-398193 https://reactome.org/PathwayBrowser/#/R-HSA-398193 PLC beta-mediated PIP2 hydrolysis TAS Homo sapiens 203600 R-HSA-399998 https://reactome.org/PathwayBrowser/#/R-HSA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate TAS Homo sapiens 203600 R-HSA-4420052 https://reactome.org/PathwayBrowser/#/R-HSA-4420052 Decreasing cGMP concentration promotes intracellular Ca2+ release in response to WNT IEA Homo sapiens 203600 R-HSA-5226904 https://reactome.org/PathwayBrowser/#/R-HSA-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it TAS Homo sapiens 203600 R-HSA-5607735 https://reactome.org/PathwayBrowser/#/R-HSA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 TAS Homo sapiens 203600 R-HSA-622382 https://reactome.org/PathwayBrowser/#/R-HSA-622382 PIP2 hydrolysis IEA Homo sapiens 203600 R-HSA-9032478 https://reactome.org/PathwayBrowser/#/R-HSA-9032478 EPOR-associated PLCG hydrolyzes 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate IEA Homo sapiens 203600 R-HSA-9717205 https://reactome.org/PathwayBrowser/#/R-HSA-9717205 GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG IEA Homo sapiens 203600 R-HSA-9717214 https://reactome.org/PathwayBrowser/#/R-HSA-9717214 I(1,4,5)P3 binds ITPR3 tetramer TAS Homo sapiens 203600 R-HSA-9717215 https://reactome.org/PathwayBrowser/#/R-HSA-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol TAS Homo sapiens 203600 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus 203600 R-MMU-111879 https://reactome.org/PathwayBrowser/#/R-MMU-111879 PIP2 hydrolysis IEA Mus musculus 203600 R-MMU-114688 https://reactome.org/PathwayBrowser/#/R-MMU-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Mus musculus 203600 R-MMU-114689 https://reactome.org/PathwayBrowser/#/R-MMU-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Mus musculus 203600 R-MMU-1168376 https://reactome.org/PathwayBrowser/#/R-MMU-1168376 STIM1 oligomerizes IEA Mus musculus 203600 R-MMU-139854 https://reactome.org/PathwayBrowser/#/R-MMU-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Mus musculus 203600 R-MMU-139941 https://reactome.org/PathwayBrowser/#/R-MMU-139941 Binding of IP3 to IP3 receptor IEA Mus musculus 203600 R-MMU-1855153 https://reactome.org/PathwayBrowser/#/R-MMU-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Mus musculus 203600 R-MMU-1855174 https://reactome.org/PathwayBrowser/#/R-MMU-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Mus musculus 203600 R-MMU-1855177 https://reactome.org/PathwayBrowser/#/R-MMU-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Mus musculus 203600 R-MMU-1855200 https://reactome.org/PathwayBrowser/#/R-MMU-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Mus musculus 203600 R-MMU-1855205 https://reactome.org/PathwayBrowser/#/R-MMU-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Mus musculus 203600 R-MMU-1855214 https://reactome.org/PathwayBrowser/#/R-MMU-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Mus musculus 203600 R-MMU-1855221 https://reactome.org/PathwayBrowser/#/R-MMU-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Mus musculus 203600 R-MMU-1855222 https://reactome.org/PathwayBrowser/#/R-MMU-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Mus musculus 203600 R-MMU-1855233 https://reactome.org/PathwayBrowser/#/R-MMU-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Mus musculus 203600 R-MMU-202407 https://reactome.org/PathwayBrowser/#/R-MMU-202407 PLC-gamma1 hydrolyses PIP2 IEA Mus musculus 203600 R-MMU-2730847 https://reactome.org/PathwayBrowser/#/R-MMU-2730847 Hydrolysis of PIP2 by PLCG IEA Mus musculus 203600 R-MMU-381644 https://reactome.org/PathwayBrowser/#/R-MMU-381644 ER calcium channels open in response to activated PKA IEA Mus musculus 203600 R-MMU-398193 https://reactome.org/PathwayBrowser/#/R-MMU-398193 PLC beta-mediated PIP2 hydrolysis IEA Mus musculus 203600 R-MMU-399998 https://reactome.org/PathwayBrowser/#/R-MMU-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Mus musculus 203600 R-MMU-5226904 https://reactome.org/PathwayBrowser/#/R-MMU-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Mus musculus 203600 R-MMU-5607735 https://reactome.org/PathwayBrowser/#/R-MMU-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Mus musculus 203600 R-MMU-9032476 https://reactome.org/PathwayBrowser/#/R-MMU-9032476 Epor-associated Plcg hydrolyzes 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate TAS Mus musculus 203600 R-MMU-9717214 https://reactome.org/PathwayBrowser/#/R-MMU-9717214 I(1,4,5)P3 binds ITPR3 tetramer IEA Mus musculus 203600 R-MMU-9717215 https://reactome.org/PathwayBrowser/#/R-MMU-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Mus musculus 203600 R-NUL-9717576 https://reactome.org/PathwayBrowser/#/R-NUL-9717576 Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG TAS Bos taurus 203600 R-PFA-114689 https://reactome.org/PathwayBrowser/#/R-PFA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Plasmodium falciparum 203600 R-PFA-1855153 https://reactome.org/PathwayBrowser/#/R-PFA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Plasmodium falciparum 203600 R-PFA-1855174 https://reactome.org/PathwayBrowser/#/R-PFA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Plasmodium falciparum 203600 R-PFA-1855177 https://reactome.org/PathwayBrowser/#/R-PFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Plasmodium falciparum 203600 R-PFA-1855214 https://reactome.org/PathwayBrowser/#/R-PFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Plasmodium falciparum 203600 R-PFA-1855221 https://reactome.org/PathwayBrowser/#/R-PFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Plasmodium falciparum 203600 R-PFA-1855222 https://reactome.org/PathwayBrowser/#/R-PFA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Plasmodium falciparum 203600 R-PFA-1855233 https://reactome.org/PathwayBrowser/#/R-PFA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Plasmodium falciparum 203600 R-PFA-202407 https://reactome.org/PathwayBrowser/#/R-PFA-202407 PLC-gamma1 hydrolyses PIP2 IEA Plasmodium falciparum 203600 R-PFA-5607735 https://reactome.org/PathwayBrowser/#/R-PFA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Plasmodium falciparum 203600 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus 203600 R-RNO-111879 https://reactome.org/PathwayBrowser/#/R-RNO-111879 PIP2 hydrolysis IEA Rattus norvegicus 203600 R-RNO-114688 https://reactome.org/PathwayBrowser/#/R-RNO-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Rattus norvegicus 203600 R-RNO-114689 https://reactome.org/PathwayBrowser/#/R-RNO-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Rattus norvegicus 203600 R-RNO-1168376 https://reactome.org/PathwayBrowser/#/R-RNO-1168376 STIM1 oligomerizes IEA Rattus norvegicus 203600 R-RNO-139854 https://reactome.org/PathwayBrowser/#/R-RNO-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Rattus norvegicus 203600 R-RNO-139941 https://reactome.org/PathwayBrowser/#/R-RNO-139941 Binding of IP3 to IP3 receptor IEA Rattus norvegicus 203600 R-RNO-182052 https://reactome.org/PathwayBrowser/#/R-RNO-182052 IP3 binds to the IP3 receptor, opening the Ca2+ channel TAS Rattus norvegicus 203600 R-RNO-182061 https://reactome.org/PathwayBrowser/#/R-RNO-182061 Active Plcg1 hydrolyses PIP2 TAS Rattus norvegicus 203600 R-RNO-182097 https://reactome.org/PathwayBrowser/#/R-RNO-182097 Calcium release from intracellular stores by IP3 receptor activation TAS Rattus norvegicus 203600 R-RNO-1855153 https://reactome.org/PathwayBrowser/#/R-RNO-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Rattus norvegicus 203600 R-RNO-1855174 https://reactome.org/PathwayBrowser/#/R-RNO-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Rattus norvegicus 203600 R-RNO-1855177 https://reactome.org/PathwayBrowser/#/R-RNO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Rattus norvegicus 203600 R-RNO-1855200 https://reactome.org/PathwayBrowser/#/R-RNO-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Rattus norvegicus 203600 R-RNO-1855205 https://reactome.org/PathwayBrowser/#/R-RNO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Rattus norvegicus 203600 R-RNO-1855214 https://reactome.org/PathwayBrowser/#/R-RNO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Rattus norvegicus 203600 R-RNO-1855221 https://reactome.org/PathwayBrowser/#/R-RNO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Rattus norvegicus 203600 R-RNO-1855222 https://reactome.org/PathwayBrowser/#/R-RNO-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Rattus norvegicus 203600 R-RNO-1855233 https://reactome.org/PathwayBrowser/#/R-RNO-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Rattus norvegicus 203600 R-RNO-202407 https://reactome.org/PathwayBrowser/#/R-RNO-202407 PLC-gamma1 hydrolyses PIP2 IEA Rattus norvegicus 203600 R-RNO-2730847 https://reactome.org/PathwayBrowser/#/R-RNO-2730847 Hydrolysis of PIP2 by PLCG IEA Rattus norvegicus 203600 R-RNO-381644 https://reactome.org/PathwayBrowser/#/R-RNO-381644 ER calcium channels open in response to activated PKA IEA Rattus norvegicus 203600 R-RNO-399998 https://reactome.org/PathwayBrowser/#/R-RNO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Rattus norvegicus 203600 R-RNO-5226904 https://reactome.org/PathwayBrowser/#/R-RNO-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Rattus norvegicus 203600 R-RNO-5607735 https://reactome.org/PathwayBrowser/#/R-RNO-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Rattus norvegicus 203600 R-RNO-622387 https://reactome.org/PathwayBrowser/#/R-RNO-622387 PIP2 hydrolysis TAS Rattus norvegicus 203600 R-RNO-9717214 https://reactome.org/PathwayBrowser/#/R-RNO-9717214 I(1,4,5)P3 binds ITPR3 tetramer IEA Rattus norvegicus 203600 R-RNO-9717215 https://reactome.org/PathwayBrowser/#/R-RNO-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Rattus norvegicus 203600 R-SCE-111879 https://reactome.org/PathwayBrowser/#/R-SCE-111879 PIP2 hydrolysis IEA Saccharomyces cerevisiae 203600 R-SCE-114688 https://reactome.org/PathwayBrowser/#/R-SCE-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Saccharomyces cerevisiae 203600 R-SCE-114689 https://reactome.org/PathwayBrowser/#/R-SCE-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Saccharomyces cerevisiae 203600 R-SCE-1855174 https://reactome.org/PathwayBrowser/#/R-SCE-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Saccharomyces cerevisiae 203600 R-SCE-1855177 https://reactome.org/PathwayBrowser/#/R-SCE-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Saccharomyces cerevisiae 203600 R-SCE-1855205 https://reactome.org/PathwayBrowser/#/R-SCE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Saccharomyces cerevisiae 203600 R-SCE-1855214 https://reactome.org/PathwayBrowser/#/R-SCE-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Saccharomyces cerevisiae 203600 R-SCE-1855221 https://reactome.org/PathwayBrowser/#/R-SCE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Saccharomyces cerevisiae 203600 R-SCE-202407 https://reactome.org/PathwayBrowser/#/R-SCE-202407 PLC-gamma1 hydrolyses PIP2 IEA Saccharomyces cerevisiae 203600 R-SCE-399998 https://reactome.org/PathwayBrowser/#/R-SCE-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Saccharomyces cerevisiae 203600 R-SCE-5607735 https://reactome.org/PathwayBrowser/#/R-SCE-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Saccharomyces cerevisiae 203600 R-SPO-111879 https://reactome.org/PathwayBrowser/#/R-SPO-111879 PIP2 hydrolysis IEA Schizosaccharomyces pombe 203600 R-SPO-114688 https://reactome.org/PathwayBrowser/#/R-SPO-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Schizosaccharomyces pombe 203600 R-SPO-114689 https://reactome.org/PathwayBrowser/#/R-SPO-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Schizosaccharomyces pombe 203600 R-SPO-1855174 https://reactome.org/PathwayBrowser/#/R-SPO-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Schizosaccharomyces pombe 203600 R-SPO-1855177 https://reactome.org/PathwayBrowser/#/R-SPO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Schizosaccharomyces pombe 203600 R-SPO-1855205 https://reactome.org/PathwayBrowser/#/R-SPO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Schizosaccharomyces pombe 203600 R-SPO-1855214 https://reactome.org/PathwayBrowser/#/R-SPO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Schizosaccharomyces pombe 203600 R-SPO-1855221 https://reactome.org/PathwayBrowser/#/R-SPO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Schizosaccharomyces pombe 203600 R-SPO-1855222 https://reactome.org/PathwayBrowser/#/R-SPO-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Schizosaccharomyces pombe 203600 R-SPO-202407 https://reactome.org/PathwayBrowser/#/R-SPO-202407 PLC-gamma1 hydrolyses PIP2 IEA Schizosaccharomyces pombe 203600 R-SPO-399998 https://reactome.org/PathwayBrowser/#/R-SPO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Schizosaccharomyces pombe 203600 R-SPO-5607735 https://reactome.org/PathwayBrowser/#/R-SPO-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Schizosaccharomyces pombe 203600 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa 203600 R-SSC-111879 https://reactome.org/PathwayBrowser/#/R-SSC-111879 PIP2 hydrolysis IEA Sus scrofa 203600 R-SSC-114688 https://reactome.org/PathwayBrowser/#/R-SSC-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Sus scrofa 203600 R-SSC-114689 https://reactome.org/PathwayBrowser/#/R-SSC-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Sus scrofa 203600 R-SSC-1168376 https://reactome.org/PathwayBrowser/#/R-SSC-1168376 STIM1 oligomerizes IEA Sus scrofa 203600 R-SSC-139854 https://reactome.org/PathwayBrowser/#/R-SSC-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Sus scrofa 203600 R-SSC-139941 https://reactome.org/PathwayBrowser/#/R-SSC-139941 Binding of IP3 to IP3 receptor IEA Sus scrofa 203600 R-SSC-1855153 https://reactome.org/PathwayBrowser/#/R-SSC-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Sus scrofa 203600 R-SSC-1855174 https://reactome.org/PathwayBrowser/#/R-SSC-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Sus scrofa 203600 R-SSC-1855177 https://reactome.org/PathwayBrowser/#/R-SSC-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Sus scrofa 203600 R-SSC-1855200 https://reactome.org/PathwayBrowser/#/R-SSC-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Sus scrofa 203600 R-SSC-1855205 https://reactome.org/PathwayBrowser/#/R-SSC-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Sus scrofa 203600 R-SSC-1855214 https://reactome.org/PathwayBrowser/#/R-SSC-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Sus scrofa 203600 R-SSC-1855221 https://reactome.org/PathwayBrowser/#/R-SSC-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Sus scrofa 203600 R-SSC-1855222 https://reactome.org/PathwayBrowser/#/R-SSC-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Sus scrofa 203600 R-SSC-202407 https://reactome.org/PathwayBrowser/#/R-SSC-202407 PLC-gamma1 hydrolyses PIP2 IEA Sus scrofa 203600 R-SSC-2730847 https://reactome.org/PathwayBrowser/#/R-SSC-2730847 Hydrolysis of PIP2 by PLCG IEA Sus scrofa 203600 R-SSC-381644 https://reactome.org/PathwayBrowser/#/R-SSC-381644 ER calcium channels open in response to activated PKA IEA Sus scrofa 203600 R-SSC-398193 https://reactome.org/PathwayBrowser/#/R-SSC-398193 PLC beta-mediated PIP2 hydrolysis IEA Sus scrofa 203600 R-SSC-399998 https://reactome.org/PathwayBrowser/#/R-SSC-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Sus scrofa 203600 R-SSC-5226904 https://reactome.org/PathwayBrowser/#/R-SSC-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Sus scrofa 203600 R-SSC-5607735 https://reactome.org/PathwayBrowser/#/R-SSC-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Sus scrofa 203600 R-SSC-9717214 https://reactome.org/PathwayBrowser/#/R-SSC-9717214 I(1,4,5)P3 binds ITPR3 tetramer IEA Sus scrofa 203600 R-SSC-9717215 https://reactome.org/PathwayBrowser/#/R-SSC-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Sus scrofa 203600 R-XTR-111879 https://reactome.org/PathwayBrowser/#/R-XTR-111879 PIP2 hydrolysis IEA Xenopus tropicalis 203600 R-XTR-114688 https://reactome.org/PathwayBrowser/#/R-XTR-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Xenopus tropicalis 203600 R-XTR-114689 https://reactome.org/PathwayBrowser/#/R-XTR-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Xenopus tropicalis 203600 R-XTR-1168376 https://reactome.org/PathwayBrowser/#/R-XTR-1168376 STIM1 oligomerizes IEA Xenopus tropicalis 203600 R-XTR-139854 https://reactome.org/PathwayBrowser/#/R-XTR-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Xenopus tropicalis 203600 R-XTR-139941 https://reactome.org/PathwayBrowser/#/R-XTR-139941 Binding of IP3 to IP3 receptor IEA Xenopus tropicalis 203600 R-XTR-1855174 https://reactome.org/PathwayBrowser/#/R-XTR-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Xenopus tropicalis 203600 R-XTR-1855177 https://reactome.org/PathwayBrowser/#/R-XTR-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Xenopus tropicalis 203600 R-XTR-1855200 https://reactome.org/PathwayBrowser/#/R-XTR-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Xenopus tropicalis 203600 R-XTR-1855205 https://reactome.org/PathwayBrowser/#/R-XTR-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Xenopus tropicalis 203600 R-XTR-1855214 https://reactome.org/PathwayBrowser/#/R-XTR-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Xenopus tropicalis 203600 R-XTR-1855221 https://reactome.org/PathwayBrowser/#/R-XTR-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Xenopus tropicalis 203600 R-XTR-1855222 https://reactome.org/PathwayBrowser/#/R-XTR-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Xenopus tropicalis 203600 R-XTR-1855233 https://reactome.org/PathwayBrowser/#/R-XTR-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Xenopus tropicalis 203600 R-XTR-202407 https://reactome.org/PathwayBrowser/#/R-XTR-202407 PLC-gamma1 hydrolyses PIP2 IEA Xenopus tropicalis 203600 R-XTR-2730847 https://reactome.org/PathwayBrowser/#/R-XTR-2730847 Hydrolysis of PIP2 by PLCG IEA Xenopus tropicalis 203600 R-XTR-381644 https://reactome.org/PathwayBrowser/#/R-XTR-381644 ER calcium channels open in response to activated PKA IEA Xenopus tropicalis 203600 R-XTR-398193 https://reactome.org/PathwayBrowser/#/R-XTR-398193 PLC beta-mediated PIP2 hydrolysis IEA Xenopus tropicalis 203600 R-XTR-5607735 https://reactome.org/PathwayBrowser/#/R-XTR-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Xenopus tropicalis 203600 R-XTR-9717214 https://reactome.org/PathwayBrowser/#/R-XTR-9717214 I(1,4,5)P3 binds ITPR3 tetramer IEA Xenopus tropicalis 203600 R-XTR-9717215 https://reactome.org/PathwayBrowser/#/R-XTR-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Xenopus tropicalis 20680 R-BTA-71130 https://reactome.org/PathwayBrowser/#/R-BTA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Bos taurus 20680 R-BTA-71146 https://reactome.org/PathwayBrowser/#/R-BTA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Bos taurus 20680 R-CEL-71130 https://reactome.org/PathwayBrowser/#/R-CEL-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Caenorhabditis elegans 20680 R-CEL-71146 https://reactome.org/PathwayBrowser/#/R-CEL-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Caenorhabditis elegans 20680 R-CFA-71130 https://reactome.org/PathwayBrowser/#/R-CFA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Canis familiaris 20680 R-CFA-71146 https://reactome.org/PathwayBrowser/#/R-CFA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Canis familiaris 20680 R-DDI-71130 https://reactome.org/PathwayBrowser/#/R-DDI-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Dictyostelium discoideum 20680 R-DDI-71146 https://reactome.org/PathwayBrowser/#/R-DDI-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Dictyostelium discoideum 20680 R-DME-71130 https://reactome.org/PathwayBrowser/#/R-DME-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Drosophila melanogaster 20680 R-DME-71146 https://reactome.org/PathwayBrowser/#/R-DME-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Drosophila melanogaster 20680 R-DRE-71130 https://reactome.org/PathwayBrowser/#/R-DRE-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Danio rerio 20680 R-DRE-71146 https://reactome.org/PathwayBrowser/#/R-DRE-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Danio rerio 20680 R-GGA-71130 https://reactome.org/PathwayBrowser/#/R-GGA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Gallus gallus 20680 R-GGA-71146 https://reactome.org/PathwayBrowser/#/R-GGA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Gallus gallus 20680 R-HSA-71130 https://reactome.org/PathwayBrowser/#/R-HSA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ TAS Homo sapiens 20680 R-HSA-71146 https://reactome.org/PathwayBrowser/#/R-HSA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O TAS Homo sapiens 20680 R-MMU-71130 https://reactome.org/PathwayBrowser/#/R-MMU-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Mus musculus 20680 R-MMU-71146 https://reactome.org/PathwayBrowser/#/R-MMU-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Mus musculus 20680 R-PFA-71146 https://reactome.org/PathwayBrowser/#/R-PFA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Plasmodium falciparum 20680 R-RNO-71130 https://reactome.org/PathwayBrowser/#/R-RNO-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Rattus norvegicus 20680 R-RNO-71146 https://reactome.org/PathwayBrowser/#/R-RNO-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Rattus norvegicus 20680 R-SCE-71146 https://reactome.org/PathwayBrowser/#/R-SCE-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Saccharomyces cerevisiae 20680 R-SPO-71146 https://reactome.org/PathwayBrowser/#/R-SPO-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Schizosaccharomyces pombe 20680 R-SSC-71130 https://reactome.org/PathwayBrowser/#/R-SSC-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Sus scrofa 20680 R-SSC-71146 https://reactome.org/PathwayBrowser/#/R-SSC-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Sus scrofa 20680 R-XTR-71130 https://reactome.org/PathwayBrowser/#/R-XTR-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Xenopus tropicalis 20680 R-XTR-71146 https://reactome.org/PathwayBrowser/#/R-XTR-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Xenopus tropicalis 20794 R-BTA-429860 https://reactome.org/PathwayBrowser/#/R-BTA-429860 DCP1-DCP2 complex decaps mRNA IEA Bos taurus 20794 R-BTA-5694126 https://reactome.org/PathwayBrowser/#/R-BTA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Bos taurus 20794 R-CEL-429860 https://reactome.org/PathwayBrowser/#/R-CEL-429860 DCP1-DCP2 complex decaps mRNA IEA Caenorhabditis elegans 20794 R-CEL-5694126 https://reactome.org/PathwayBrowser/#/R-CEL-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Caenorhabditis elegans 20794 R-CFA-429860 https://reactome.org/PathwayBrowser/#/R-CFA-429860 DCP1-DCP2 complex decaps mRNA IEA Canis familiaris 20794 R-CFA-5694126 https://reactome.org/PathwayBrowser/#/R-CFA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Canis familiaris 20794 R-DDI-429860 https://reactome.org/PathwayBrowser/#/R-DDI-429860 DCP1-DCP2 complex decaps mRNA IEA Dictyostelium discoideum 20794 R-DME-429860 https://reactome.org/PathwayBrowser/#/R-DME-429860 DCP1-DCP2 complex decaps mRNA IEA Drosophila melanogaster 20794 R-DME-5694126 https://reactome.org/PathwayBrowser/#/R-DME-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Drosophila melanogaster 20794 R-DRE-429860 https://reactome.org/PathwayBrowser/#/R-DRE-429860 DCP1-DCP2 complex decaps mRNA IEA Danio rerio 20794 R-GGA-429860 https://reactome.org/PathwayBrowser/#/R-GGA-429860 DCP1-DCP2 complex decaps mRNA IEA Gallus gallus 20794 R-GGA-5694126 https://reactome.org/PathwayBrowser/#/R-GGA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Gallus gallus 20794 R-HSA-429860 https://reactome.org/PathwayBrowser/#/R-HSA-429860 DCP1-DCP2 complex decaps mRNA TAS Homo sapiens 20794 R-HSA-5694126 https://reactome.org/PathwayBrowser/#/R-HSA-5694126 NT5C3B hydrolyses 7MGP to 7MG TAS Homo sapiens 20794 R-HSA-6790982 https://reactome.org/PathwayBrowser/#/R-HSA-6790982 WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639 TAS Homo sapiens 20794 R-HSA-6790994 https://reactome.org/PathwayBrowser/#/R-HSA-6790994 DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851 TAS Homo sapiens 20794 R-MMU-429860 https://reactome.org/PathwayBrowser/#/R-MMU-429860 DCP1-DCP2 complex decaps mRNA IEA Mus musculus 20794 R-MMU-5694126 https://reactome.org/PathwayBrowser/#/R-MMU-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Mus musculus 20794 R-PFA-429860 https://reactome.org/PathwayBrowser/#/R-PFA-429860 DCP1-DCP2 complex decaps mRNA IEA Plasmodium falciparum 20794 R-RNO-429860 https://reactome.org/PathwayBrowser/#/R-RNO-429860 DCP1-DCP2 complex decaps mRNA IEA Rattus norvegicus 20794 R-RNO-5694126 https://reactome.org/PathwayBrowser/#/R-RNO-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Rattus norvegicus 20794 R-SCE-429860 https://reactome.org/PathwayBrowser/#/R-SCE-429860 DCP1-DCP2 complex decaps mRNA IEA Saccharomyces cerevisiae 20794 R-SSC-429860 https://reactome.org/PathwayBrowser/#/R-SSC-429860 DCP1-DCP2 complex decaps mRNA IEA Sus scrofa 20794 R-SSC-5694126 https://reactome.org/PathwayBrowser/#/R-SSC-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Sus scrofa 20794 R-XTR-429860 https://reactome.org/PathwayBrowser/#/R-XTR-429860 DCP1-DCP2 complex decaps mRNA IEA Xenopus tropicalis 20794 R-XTR-5694126 https://reactome.org/PathwayBrowser/#/R-XTR-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Xenopus tropicalis 21338 R-BTA-1678716 https://reactome.org/PathwayBrowser/#/R-BTA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Bos taurus 21338 R-BTA-1793186 https://reactome.org/PathwayBrowser/#/R-BTA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Bos taurus 21338 R-BTA-2090037 https://reactome.org/PathwayBrowser/#/R-BTA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Bos taurus 21338 R-CFA-1678716 https://reactome.org/PathwayBrowser/#/R-CFA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Canis familiaris 21338 R-CFA-1793186 https://reactome.org/PathwayBrowser/#/R-CFA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Canis familiaris 21338 R-CFA-2090037 https://reactome.org/PathwayBrowser/#/R-CFA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Canis familiaris 21338 R-DDI-1678716 https://reactome.org/PathwayBrowser/#/R-DDI-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Dictyostelium discoideum 21338 R-DDI-1793186 https://reactome.org/PathwayBrowser/#/R-DDI-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Dictyostelium discoideum 21338 R-DDI-2090037 https://reactome.org/PathwayBrowser/#/R-DDI-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Dictyostelium discoideum 21338 R-DME-1678716 https://reactome.org/PathwayBrowser/#/R-DME-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Drosophila melanogaster 21338 R-DME-1793186 https://reactome.org/PathwayBrowser/#/R-DME-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Drosophila melanogaster 21338 R-DME-2090037 https://reactome.org/PathwayBrowser/#/R-DME-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Drosophila melanogaster 21338 R-GGA-1678716 https://reactome.org/PathwayBrowser/#/R-GGA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Gallus gallus 21338 R-GGA-1793186 https://reactome.org/PathwayBrowser/#/R-GGA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Gallus gallus 21338 R-GGA-2090037 https://reactome.org/PathwayBrowser/#/R-GGA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Gallus gallus 21338 R-HSA-1678716 https://reactome.org/PathwayBrowser/#/R-HSA-1678716 IDUA hydrolyses Heparan sulfate chain(1) TAS Homo sapiens 21338 R-HSA-1793186 https://reactome.org/PathwayBrowser/#/R-HSA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS TAS Homo sapiens 21338 R-HSA-2090037 https://reactome.org/PathwayBrowser/#/R-HSA-2090037 IDUA hydrolyses Heparan sulfate chain(6) TAS Homo sapiens 21338 R-MMU-1678716 https://reactome.org/PathwayBrowser/#/R-MMU-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Mus musculus 21338 R-MMU-1793186 https://reactome.org/PathwayBrowser/#/R-MMU-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Mus musculus 21338 R-MMU-2090037 https://reactome.org/PathwayBrowser/#/R-MMU-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Mus musculus 21338 R-RNO-1678716 https://reactome.org/PathwayBrowser/#/R-RNO-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Rattus norvegicus 21338 R-RNO-1793186 https://reactome.org/PathwayBrowser/#/R-RNO-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Rattus norvegicus 21338 R-RNO-2090037 https://reactome.org/PathwayBrowser/#/R-RNO-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Rattus norvegicus 21338 R-SSC-1678716 https://reactome.org/PathwayBrowser/#/R-SSC-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Sus scrofa 21338 R-SSC-1793186 https://reactome.org/PathwayBrowser/#/R-SSC-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Sus scrofa 21338 R-SSC-2090037 https://reactome.org/PathwayBrowser/#/R-SSC-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Sus scrofa 21338 R-XTR-1678716 https://reactome.org/PathwayBrowser/#/R-XTR-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Xenopus tropicalis 21338 R-XTR-1793186 https://reactome.org/PathwayBrowser/#/R-XTR-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Xenopus tropicalis 21338 R-XTR-2090037 https://reactome.org/PathwayBrowser/#/R-XTR-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Xenopus tropicalis 21347 R-BTA-1614591 https://reactome.org/PathwayBrowser/#/R-BTA-1614591 Excess cysteine yields lanthionine and H2S IEA Bos taurus 21347 R-CEL-1614591 https://reactome.org/PathwayBrowser/#/R-CEL-1614591 Excess cysteine yields lanthionine and H2S IEA Caenorhabditis elegans 21347 R-CFA-1614591 https://reactome.org/PathwayBrowser/#/R-CFA-1614591 Excess cysteine yields lanthionine and H2S IEA Canis familiaris 21347 R-DDI-1614591 https://reactome.org/PathwayBrowser/#/R-DDI-1614591 Excess cysteine yields lanthionine and H2S IEA Dictyostelium discoideum 21347 R-DME-1614591 https://reactome.org/PathwayBrowser/#/R-DME-1614591 Excess cysteine yields lanthionine and H2S IEA Drosophila melanogaster 21347 R-DRE-1614591 https://reactome.org/PathwayBrowser/#/R-DRE-1614591 Excess cysteine yields lanthionine and H2S IEA Danio rerio 21347 R-GGA-1614591 https://reactome.org/PathwayBrowser/#/R-GGA-1614591 Excess cysteine yields lanthionine and H2S IEA Gallus gallus 21347 R-HSA-1614591 https://reactome.org/PathwayBrowser/#/R-HSA-1614591 Excess cysteine yields lanthionine and H2S TAS Homo sapiens 21347 R-MMU-1614591 https://reactome.org/PathwayBrowser/#/R-MMU-1614591 Excess cysteine yields lanthionine and H2S IEA Mus musculus 21347 R-RNO-1614591 https://reactome.org/PathwayBrowser/#/R-RNO-1614591 Excess cysteine yields lanthionine and H2S IEA Rattus norvegicus 21347 R-SCE-1614591 https://reactome.org/PathwayBrowser/#/R-SCE-1614591 Excess cysteine yields lanthionine and H2S IEA Saccharomyces cerevisiae 21347 R-SPO-1614591 https://reactome.org/PathwayBrowser/#/R-SPO-1614591 Excess cysteine yields lanthionine and H2S IEA Schizosaccharomyces pombe 21347 R-SSC-1614591 https://reactome.org/PathwayBrowser/#/R-SSC-1614591 Excess cysteine yields lanthionine and H2S IEA Sus scrofa 21347 R-XTR-1614591 https://reactome.org/PathwayBrowser/#/R-XTR-1614591 Excess cysteine yields lanthionine and H2S IEA Xenopus tropicalis 21363 R-HSA-5676926 https://reactome.org/PathwayBrowser/#/R-HSA-5676926 Methionine sulfoxide is oxidised to methionine sulfone TAS Homo sapiens 21437 R-BTA-8936442 https://reactome.org/PathwayBrowser/#/R-BTA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Bos taurus 21437 R-CEL-8936442 https://reactome.org/PathwayBrowser/#/R-CEL-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Caenorhabditis elegans 21437 R-CFA-8936442 https://reactome.org/PathwayBrowser/#/R-CFA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Canis familiaris 21437 R-DDI-8936442 https://reactome.org/PathwayBrowser/#/R-DDI-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Dictyostelium discoideum 21437 R-DME-8936442 https://reactome.org/PathwayBrowser/#/R-DME-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Drosophila melanogaster 21437 R-DRE-8936442 https://reactome.org/PathwayBrowser/#/R-DRE-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Danio rerio 21437 R-GGA-8936442 https://reactome.org/PathwayBrowser/#/R-GGA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Gallus gallus 21437 R-HSA-8936442 https://reactome.org/PathwayBrowser/#/R-HSA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds TAS Homo sapiens 21437 R-MMU-8936442 https://reactome.org/PathwayBrowser/#/R-MMU-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Mus musculus 21437 R-RNO-8936442 https://reactome.org/PathwayBrowser/#/R-RNO-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Rattus norvegicus 21437 R-SSC-8936442 https://reactome.org/PathwayBrowser/#/R-SSC-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Sus scrofa 21437 R-XTR-8936442 https://reactome.org/PathwayBrowser/#/R-XTR-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Xenopus tropicalis 21507 R-BTA-4084980 https://reactome.org/PathwayBrowser/#/R-BTA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Bos taurus 21507 R-BTA-4084999 https://reactome.org/PathwayBrowser/#/R-BTA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 21507 R-BTA-4085029 https://reactome.org/PathwayBrowser/#/R-BTA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 21507 R-BTA-9638120 https://reactome.org/PathwayBrowser/#/R-BTA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 21507 R-CFA-4084980 https://reactome.org/PathwayBrowser/#/R-CFA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Canis familiaris 21507 R-CFA-4084999 https://reactome.org/PathwayBrowser/#/R-CFA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 21507 R-CFA-4085029 https://reactome.org/PathwayBrowser/#/R-CFA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 21507 R-CFA-9638120 https://reactome.org/PathwayBrowser/#/R-CFA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 21507 R-DRE-4084980 https://reactome.org/PathwayBrowser/#/R-DRE-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Danio rerio 21507 R-DRE-4085029 https://reactome.org/PathwayBrowser/#/R-DRE-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 21507 R-GGA-4084980 https://reactome.org/PathwayBrowser/#/R-GGA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Gallus gallus 21507 R-GGA-4085029 https://reactome.org/PathwayBrowser/#/R-GGA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 21507 R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus 21507 R-HSA-4084980 https://reactome.org/PathwayBrowser/#/R-HSA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) TAS Homo sapiens 21507 R-HSA-4084999 https://reactome.org/PathwayBrowser/#/R-HSA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 21507 R-HSA-4085029 https://reactome.org/PathwayBrowser/#/R-HSA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 21507 R-HSA-9638120 https://reactome.org/PathwayBrowser/#/R-HSA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 21507 R-MMU-4084980 https://reactome.org/PathwayBrowser/#/R-MMU-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Mus musculus 21507 R-MMU-4084999 https://reactome.org/PathwayBrowser/#/R-MMU-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 21507 R-MMU-4085029 https://reactome.org/PathwayBrowser/#/R-MMU-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 21507 R-MMU-9638120 https://reactome.org/PathwayBrowser/#/R-MMU-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 21507 R-RNO-4084980 https://reactome.org/PathwayBrowser/#/R-RNO-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Rattus norvegicus 21507 R-RNO-4084999 https://reactome.org/PathwayBrowser/#/R-RNO-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 21507 R-RNO-4085029 https://reactome.org/PathwayBrowser/#/R-RNO-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 21507 R-RNO-9638120 https://reactome.org/PathwayBrowser/#/R-RNO-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 21507 R-SSC-4084980 https://reactome.org/PathwayBrowser/#/R-SSC-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Sus scrofa 21507 R-SSC-4084999 https://reactome.org/PathwayBrowser/#/R-SSC-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 21507 R-SSC-4085029 https://reactome.org/PathwayBrowser/#/R-SSC-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 21507 R-SSC-9638120 https://reactome.org/PathwayBrowser/#/R-SSC-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 21507 R-XTR-4084980 https://reactome.org/PathwayBrowser/#/R-XTR-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Xenopus tropicalis 21507 R-XTR-4084999 https://reactome.org/PathwayBrowser/#/R-XTR-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 21507 R-XTR-4085029 https://reactome.org/PathwayBrowser/#/R-XTR-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 21507 R-XTR-9638120 https://reactome.org/PathwayBrowser/#/R-XTR-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 21547 R-BTA-5691507 https://reactome.org/PathwayBrowser/#/R-BTA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Bos taurus 21547 R-BTA-8942575 https://reactome.org/PathwayBrowser/#/R-BTA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Bos taurus 21547 R-BTA-8954468 https://reactome.org/PathwayBrowser/#/R-BTA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Bos taurus 21547 R-CFA-5691507 https://reactome.org/PathwayBrowser/#/R-CFA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Canis familiaris 21547 R-CFA-8942575 https://reactome.org/PathwayBrowser/#/R-CFA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Canis familiaris 21547 R-CFA-8954468 https://reactome.org/PathwayBrowser/#/R-CFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Canis familiaris 21547 R-DDI-8954468 https://reactome.org/PathwayBrowser/#/R-DDI-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Dictyostelium discoideum 21547 R-DRE-5691507 https://reactome.org/PathwayBrowser/#/R-DRE-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Danio rerio 21547 R-DRE-8942575 https://reactome.org/PathwayBrowser/#/R-DRE-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Danio rerio 21547 R-DRE-8954468 https://reactome.org/PathwayBrowser/#/R-DRE-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Danio rerio 21547 R-GGA-5691507 https://reactome.org/PathwayBrowser/#/R-GGA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Gallus gallus 21547 R-GGA-8942575 https://reactome.org/PathwayBrowser/#/R-GGA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Gallus gallus 21547 R-GGA-8954468 https://reactome.org/PathwayBrowser/#/R-GGA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Gallus gallus 21547 R-HSA-5691507 https://reactome.org/PathwayBrowser/#/R-HSA-5691507 ASPA deacetylates NAA to acetate and L-aspartate TAS Homo sapiens 21547 R-HSA-8942575 https://reactome.org/PathwayBrowser/#/R-HSA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG TAS Homo sapiens 21547 R-HSA-8954468 https://reactome.org/PathwayBrowser/#/R-HSA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA TAS Homo sapiens 21547 R-HSA-8954513 https://reactome.org/PathwayBrowser/#/R-HSA-8954513 NAA translocates from mitochondrial matrix to cytosol TAS Homo sapiens 21547 R-MMU-5691507 https://reactome.org/PathwayBrowser/#/R-MMU-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Mus musculus 21547 R-MMU-8942575 https://reactome.org/PathwayBrowser/#/R-MMU-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Mus musculus 21547 R-MMU-8954468 https://reactome.org/PathwayBrowser/#/R-MMU-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Mus musculus 21547 R-PFA-8954468 https://reactome.org/PathwayBrowser/#/R-PFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Plasmodium falciparum 21547 R-RNO-5691507 https://reactome.org/PathwayBrowser/#/R-RNO-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Rattus norvegicus 21547 R-RNO-8942575 https://reactome.org/PathwayBrowser/#/R-RNO-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Rattus norvegicus 21547 R-RNO-8954468 https://reactome.org/PathwayBrowser/#/R-RNO-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Rattus norvegicus 21547 R-SSC-5691507 https://reactome.org/PathwayBrowser/#/R-SSC-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Sus scrofa 21547 R-SSC-8942575 https://reactome.org/PathwayBrowser/#/R-SSC-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Sus scrofa 21547 R-SSC-8954468 https://reactome.org/PathwayBrowser/#/R-SSC-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Sus scrofa 21547 R-XTR-5691507 https://reactome.org/PathwayBrowser/#/R-XTR-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Xenopus tropicalis 21547 R-XTR-8942575 https://reactome.org/PathwayBrowser/#/R-XTR-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Xenopus tropicalis 21547 R-XTR-8954468 https://reactome.org/PathwayBrowser/#/R-XTR-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Xenopus tropicalis 21615 R-BTA-8862320 https://reactome.org/PathwayBrowser/#/R-BTA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Bos taurus 21615 R-CFA-8862320 https://reactome.org/PathwayBrowser/#/R-CFA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Canis familiaris 21615 R-DDI-8862320 https://reactome.org/PathwayBrowser/#/R-DDI-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Dictyostelium discoideum 21615 R-DME-8862320 https://reactome.org/PathwayBrowser/#/R-DME-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Drosophila melanogaster 21615 R-DRE-8862320 https://reactome.org/PathwayBrowser/#/R-DRE-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Danio rerio 21615 R-GGA-8862320 https://reactome.org/PathwayBrowser/#/R-GGA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Gallus gallus 21615 R-HSA-6789208 https://reactome.org/PathwayBrowser/#/R-HSA-6789208 HOCl-induced glycosaminoglycan fragmentation TAS Homo sapiens 21615 R-HSA-8862320 https://reactome.org/PathwayBrowser/#/R-HSA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall TAS Homo sapiens 21615 R-MMU-8862320 https://reactome.org/PathwayBrowser/#/R-MMU-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Mus musculus 21615 R-RNO-8862320 https://reactome.org/PathwayBrowser/#/R-RNO-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Rattus norvegicus 21615 R-SSC-8862320 https://reactome.org/PathwayBrowser/#/R-SSC-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Sus scrofa 21615 R-XTR-8862320 https://reactome.org/PathwayBrowser/#/R-XTR-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Xenopus tropicalis 2181 R-BTA-2203480 https://reactome.org/PathwayBrowser/#/R-BTA-2203480 COLEC11 binds ligands IEA Bos taurus 2181 R-BTA-5693807 https://reactome.org/PathwayBrowser/#/R-BTA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Bos taurus 2181 R-CEL-5693807 https://reactome.org/PathwayBrowser/#/R-CEL-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Caenorhabditis elegans 2181 R-CFA-5693807 https://reactome.org/PathwayBrowser/#/R-CFA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Canis familiaris 2181 R-DDI-5693807 https://reactome.org/PathwayBrowser/#/R-DDI-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Dictyostelium discoideum 2181 R-DME-5693807 https://reactome.org/PathwayBrowser/#/R-DME-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Drosophila melanogaster 2181 R-DRE-5693807 https://reactome.org/PathwayBrowser/#/R-DRE-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Danio rerio 2181 R-GGA-2203480 https://reactome.org/PathwayBrowser/#/R-GGA-2203480 COLEC11 binds ligands IEA Gallus gallus 2181 R-GGA-5693807 https://reactome.org/PathwayBrowser/#/R-GGA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Gallus gallus 2181 R-HSA-2203480 https://reactome.org/PathwayBrowser/#/R-HSA-2203480 COLEC11 binds ligands TAS Homo sapiens 2181 R-HSA-5693807 https://reactome.org/PathwayBrowser/#/R-HSA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc TAS Homo sapiens 2181 R-MMU-2203480 https://reactome.org/PathwayBrowser/#/R-MMU-2203480 COLEC11 binds ligands IEA Mus musculus 2181 R-MMU-5693807 https://reactome.org/PathwayBrowser/#/R-MMU-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Mus musculus 2181 R-RNO-5693807 https://reactome.org/PathwayBrowser/#/R-RNO-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Rattus norvegicus 2181 R-SSC-2203480 https://reactome.org/PathwayBrowser/#/R-SSC-2203480 COLEC11 binds ligands IEA Sus scrofa 2181 R-SSC-5693807 https://reactome.org/PathwayBrowser/#/R-SSC-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Sus scrofa 2181 R-XTR-5693807 https://reactome.org/PathwayBrowser/#/R-XTR-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Xenopus tropicalis 21891 R-BTA-8857692 https://reactome.org/PathwayBrowser/#/R-BTA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Bos taurus 21891 R-CFA-8857692 https://reactome.org/PathwayBrowser/#/R-CFA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Canis familiaris 21891 R-DRE-8857692 https://reactome.org/PathwayBrowser/#/R-DRE-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Danio rerio 21891 R-GGA-8857692 https://reactome.org/PathwayBrowser/#/R-GGA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Gallus gallus 21891 R-HSA-8857692 https://reactome.org/PathwayBrowser/#/R-HSA-8857692 RNA demethylases demethylate N6-methyladenosine RNA TAS Homo sapiens 21891 R-MMU-8857692 https://reactome.org/PathwayBrowser/#/R-MMU-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Mus musculus 21891 R-RNO-8857692 https://reactome.org/PathwayBrowser/#/R-RNO-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Rattus norvegicus 21891 R-SSC-8857692 https://reactome.org/PathwayBrowser/#/R-SSC-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Sus scrofa 21891 R-XTR-8857692 https://reactome.org/PathwayBrowser/#/R-XTR-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Xenopus tropicalis 2208 R-BTA-158609 https://reactome.org/PathwayBrowser/#/R-BTA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Bos taurus 2208 R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 2208 R-CFA-158609 https://reactome.org/PathwayBrowser/#/R-CFA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Canis familiaris 2208 R-DRE-158609 https://reactome.org/PathwayBrowser/#/R-DRE-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Danio rerio 2208 R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 2208 R-GGA-158609 https://reactome.org/PathwayBrowser/#/R-GGA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Gallus gallus 2208 R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 2208 R-HSA-158609 https://reactome.org/PathwayBrowser/#/R-HSA-158609 TPMT transfers CH3 from AdoMet to 6MP TAS Homo sapiens 2208 R-HSA-5603379 https://reactome.org/PathwayBrowser/#/R-HSA-5603379 TPMT does not transfer CH3 from AdoMet to 6MP TAS Homo sapiens 2208 R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 2208 R-MMU-158609 https://reactome.org/PathwayBrowser/#/R-MMU-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Mus musculus 2208 R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 2208 R-RNO-158609 https://reactome.org/PathwayBrowser/#/R-RNO-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Rattus norvegicus 2208 R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 2208 R-SSC-158609 https://reactome.org/PathwayBrowser/#/R-SSC-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Sus scrofa 2208 R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 2208 R-XTR-158609 https://reactome.org/PathwayBrowser/#/R-XTR-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Xenopus tropicalis 22221 R-BTA-5694583 https://reactome.org/PathwayBrowser/#/R-BTA-5694583 ABHD4 hydrolyses NAPE IEA Bos taurus 22221 R-CEL-5694583 https://reactome.org/PathwayBrowser/#/R-CEL-5694583 ABHD4 hydrolyses NAPE IEA Caenorhabditis elegans 22221 R-CFA-5694583 https://reactome.org/PathwayBrowser/#/R-CFA-5694583 ABHD4 hydrolyses NAPE IEA Canis familiaris 22221 R-DME-5694583 https://reactome.org/PathwayBrowser/#/R-DME-5694583 ABHD4 hydrolyses NAPE IEA Drosophila melanogaster 22221 R-HSA-5694583 https://reactome.org/PathwayBrowser/#/R-HSA-5694583 ABHD4 hydrolyses NAPE TAS Homo sapiens 22221 R-MMU-5694583 https://reactome.org/PathwayBrowser/#/R-MMU-5694583 ABHD4 hydrolyses NAPE IEA Mus musculus 22221 R-RNO-5694583 https://reactome.org/PathwayBrowser/#/R-RNO-5694583 ABHD4 hydrolyses NAPE IEA Rattus norvegicus 22221 R-SCE-5694583 https://reactome.org/PathwayBrowser/#/R-SCE-5694583 ABHD4 hydrolyses NAPE IEA Saccharomyces cerevisiae 22221 R-SPO-5694583 https://reactome.org/PathwayBrowser/#/R-SPO-5694583 ABHD4 hydrolyses NAPE IEA Schizosaccharomyces pombe 22221 R-SSC-5694583 https://reactome.org/PathwayBrowser/#/R-SSC-5694583 ABHD4 hydrolyses NAPE IEA Sus scrofa 22221 R-XTR-5694583 https://reactome.org/PathwayBrowser/#/R-XTR-5694583 ABHD4 hydrolyses NAPE IEA Xenopus tropicalis 225238 R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 225238 R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 225238 R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 225238 R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 225238 R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 225238 R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 225238 R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa 225238 R-XTR-5696183 https://reactome.org/PathwayBrowser/#/R-XTR-5696183 AOC3 deaminates BZAM IEA Xenopus tropicalis 2274 R-BTA-191784 https://reactome.org/PathwayBrowser/#/R-BTA-191784 snRNA Cap hypermethylation IEA Bos taurus 2274 R-CEL-191784 https://reactome.org/PathwayBrowser/#/R-CEL-191784 snRNA Cap hypermethylation IEA Caenorhabditis elegans 2274 R-CFA-191784 https://reactome.org/PathwayBrowser/#/R-CFA-191784 snRNA Cap hypermethylation IEA Canis familiaris 2274 R-GGA-191784 https://reactome.org/PathwayBrowser/#/R-GGA-191784 snRNA Cap hypermethylation IEA Gallus gallus 2274 R-HSA-191784 https://reactome.org/PathwayBrowser/#/R-HSA-191784 snRNA Cap hypermethylation TAS Homo sapiens 2274 R-HSA-191786 https://reactome.org/PathwayBrowser/#/R-HSA-191786 snRNP complex assembly TAS Homo sapiens 2274 R-HSA-191825 https://reactome.org/PathwayBrowser/#/R-HSA-191825 Nuclear export of snRNA transcripts TAS Homo sapiens 2274 R-MMU-191784 https://reactome.org/PathwayBrowser/#/R-MMU-191784 snRNA Cap hypermethylation IEA Mus musculus 2274 R-RNO-191784 https://reactome.org/PathwayBrowser/#/R-RNO-191784 snRNA Cap hypermethylation IEA Rattus norvegicus 2274 R-SSC-191784 https://reactome.org/PathwayBrowser/#/R-SSC-191784 snRNA Cap hypermethylation IEA Sus scrofa 22801 R-BTA-1605591 https://reactome.org/PathwayBrowser/#/R-BTA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Bos taurus 22801 R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus 22801 R-BTA-1638104 https://reactome.org/PathwayBrowser/#/R-BTA-1638104 UGCG transfers glucose to ceramide IEA Bos taurus 22801 R-BTA-1861788 https://reactome.org/PathwayBrowser/#/R-BTA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Bos taurus 22801 R-BTA-1861789 https://reactome.org/PathwayBrowser/#/R-BTA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Bos taurus 22801 R-BTA-9845055 https://reactome.org/PathwayBrowser/#/R-BTA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Bos taurus 22801 R-BTA-9851347 https://reactome.org/PathwayBrowser/#/R-BTA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Bos taurus 22801 R-CEL-1605591 https://reactome.org/PathwayBrowser/#/R-CEL-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Caenorhabditis elegans 22801 R-CEL-1606312 https://reactome.org/PathwayBrowser/#/R-CEL-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Caenorhabditis elegans 22801 R-CEL-1638104 https://reactome.org/PathwayBrowser/#/R-CEL-1638104 UGCG transfers glucose to ceramide IEA Caenorhabditis elegans 22801 R-CEL-1861788 https://reactome.org/PathwayBrowser/#/R-CEL-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Caenorhabditis elegans 22801 R-CEL-1861789 https://reactome.org/PathwayBrowser/#/R-CEL-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Caenorhabditis elegans 22801 R-CFA-1605591 https://reactome.org/PathwayBrowser/#/R-CFA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Canis familiaris 22801 R-CFA-1606312 https://reactome.org/PathwayBrowser/#/R-CFA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Canis familiaris 22801 R-CFA-1638104 https://reactome.org/PathwayBrowser/#/R-CFA-1638104 UGCG transfers glucose to ceramide IEA Canis familiaris 22801 R-CFA-1861788 https://reactome.org/PathwayBrowser/#/R-CFA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Canis familiaris 22801 R-CFA-1861789 https://reactome.org/PathwayBrowser/#/R-CFA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Canis familiaris 22801 R-CFA-9845055 https://reactome.org/PathwayBrowser/#/R-CFA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Canis familiaris 22801 R-CFA-9851347 https://reactome.org/PathwayBrowser/#/R-CFA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Canis familiaris 22801 R-DDI-1606312 https://reactome.org/PathwayBrowser/#/R-DDI-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Dictyostelium discoideum 22801 R-DDI-1861788 https://reactome.org/PathwayBrowser/#/R-DDI-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Dictyostelium discoideum 22801 R-DME-1605591 https://reactome.org/PathwayBrowser/#/R-DME-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Drosophila melanogaster 22801 R-DME-1606312 https://reactome.org/PathwayBrowser/#/R-DME-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Drosophila melanogaster 22801 R-DME-1638104 https://reactome.org/PathwayBrowser/#/R-DME-1638104 UGCG transfers glucose to ceramide IEA Drosophila melanogaster 22801 R-DME-1861788 https://reactome.org/PathwayBrowser/#/R-DME-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Drosophila melanogaster 22801 R-DME-1861789 https://reactome.org/PathwayBrowser/#/R-DME-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Drosophila melanogaster 22801 R-DME-9851347 https://reactome.org/PathwayBrowser/#/R-DME-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Drosophila melanogaster 22801 R-DRE-1638104 https://reactome.org/PathwayBrowser/#/R-DRE-1638104 UGCG transfers glucose to ceramide IEA Danio rerio 22801 R-DRE-1861788 https://reactome.org/PathwayBrowser/#/R-DRE-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Danio rerio 22801 R-DRE-1861789 https://reactome.org/PathwayBrowser/#/R-DRE-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Danio rerio 22801 R-DRE-9845055 https://reactome.org/PathwayBrowser/#/R-DRE-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Danio rerio 22801 R-DRE-9851347 https://reactome.org/PathwayBrowser/#/R-DRE-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Danio rerio 22801 R-GGA-1605591 https://reactome.org/PathwayBrowser/#/R-GGA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Gallus gallus 22801 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus 22801 R-GGA-1638104 https://reactome.org/PathwayBrowser/#/R-GGA-1638104 UGCG transfers glucose to ceramide IEA Gallus gallus 22801 R-GGA-1861788 https://reactome.org/PathwayBrowser/#/R-GGA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Gallus gallus 22801 R-GGA-9845055 https://reactome.org/PathwayBrowser/#/R-GGA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Gallus gallus 22801 R-GGA-9851347 https://reactome.org/PathwayBrowser/#/R-GGA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Gallus gallus 22801 R-HSA-1605591 https://reactome.org/PathwayBrowser/#/R-HSA-1605591 GBA1:SAPC hydrolyzes GlcCer TAS Homo sapiens 22801 R-HSA-1606312 https://reactome.org/PathwayBrowser/#/R-HSA-1606312 GLB1 hydrolyzes SapB/C:LacCer TAS Homo sapiens 22801 R-HSA-1638104 https://reactome.org/PathwayBrowser/#/R-HSA-1638104 UGCG transfers glucose to ceramide TAS Homo sapiens 22801 R-HSA-1861788 https://reactome.org/PathwayBrowser/#/R-HSA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) TAS Homo sapiens 22801 R-HSA-1861789 https://reactome.org/PathwayBrowser/#/R-HSA-1861789 GBA3 hydrolyzes GlcCer (cytosol) TAS Homo sapiens 22801 R-HSA-9845055 https://reactome.org/PathwayBrowser/#/R-HSA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane TAS Homo sapiens 22801 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 22801 R-HSA-9851347 https://reactome.org/PathwayBrowser/#/R-HSA-9851347 B4GALT5/6 transfer Gal to GlcCer TAS Homo sapiens 22801 R-MMU-1605591 https://reactome.org/PathwayBrowser/#/R-MMU-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Mus musculus 22801 R-MMU-1606312 https://reactome.org/PathwayBrowser/#/R-MMU-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Mus musculus 22801 R-MMU-1638104 https://reactome.org/PathwayBrowser/#/R-MMU-1638104 UGCG transfers glucose to ceramide IEA Mus musculus 22801 R-MMU-1861788 https://reactome.org/PathwayBrowser/#/R-MMU-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Mus musculus 22801 R-MMU-9845055 https://reactome.org/PathwayBrowser/#/R-MMU-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Mus musculus 22801 R-MMU-9851347 https://reactome.org/PathwayBrowser/#/R-MMU-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Mus musculus 22801 R-PFA-9845055 https://reactome.org/PathwayBrowser/#/R-PFA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Plasmodium falciparum 22801 R-RNO-1605591 https://reactome.org/PathwayBrowser/#/R-RNO-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Rattus norvegicus 22801 R-RNO-1606312 https://reactome.org/PathwayBrowser/#/R-RNO-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Rattus norvegicus 22801 R-RNO-1638104 https://reactome.org/PathwayBrowser/#/R-RNO-1638104 UGCG transfers glucose to ceramide IEA Rattus norvegicus 22801 R-RNO-1861788 https://reactome.org/PathwayBrowser/#/R-RNO-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Rattus norvegicus 22801 R-RNO-1861789 https://reactome.org/PathwayBrowser/#/R-RNO-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Rattus norvegicus 22801 R-RNO-9845055 https://reactome.org/PathwayBrowser/#/R-RNO-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Rattus norvegicus 22801 R-RNO-9851347 https://reactome.org/PathwayBrowser/#/R-RNO-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Rattus norvegicus 22801 R-SSC-1605591 https://reactome.org/PathwayBrowser/#/R-SSC-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Sus scrofa 22801 R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa 22801 R-SSC-1638104 https://reactome.org/PathwayBrowser/#/R-SSC-1638104 UGCG transfers glucose to ceramide IEA Sus scrofa 22801 R-SSC-1861788 https://reactome.org/PathwayBrowser/#/R-SSC-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Sus scrofa 22801 R-SSC-1861789 https://reactome.org/PathwayBrowser/#/R-SSC-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Sus scrofa 22801 R-SSC-9845055 https://reactome.org/PathwayBrowser/#/R-SSC-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Sus scrofa 22801 R-SSC-9851347 https://reactome.org/PathwayBrowser/#/R-SSC-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Sus scrofa 22801 R-XTR-1638104 https://reactome.org/PathwayBrowser/#/R-XTR-1638104 UGCG transfers glucose to ceramide IEA Xenopus tropicalis 22801 R-XTR-9845055 https://reactome.org/PathwayBrowser/#/R-XTR-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Xenopus tropicalis 22801 R-XTR-9851347 https://reactome.org/PathwayBrowser/#/R-XTR-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Xenopus tropicalis 2288 R-BTA-192036 https://reactome.org/PathwayBrowser/#/R-BTA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Bos taurus 2288 R-BTA-192067 https://reactome.org/PathwayBrowser/#/R-BTA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Bos taurus 2288 R-CEL-192036 https://reactome.org/PathwayBrowser/#/R-CEL-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Caenorhabditis elegans 2288 R-CEL-192067 https://reactome.org/PathwayBrowser/#/R-CEL-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Caenorhabditis elegans 2288 R-CFA-192067 https://reactome.org/PathwayBrowser/#/R-CFA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Canis familiaris 2288 R-DDI-192036 https://reactome.org/PathwayBrowser/#/R-DDI-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Dictyostelium discoideum 2288 R-DDI-192067 https://reactome.org/PathwayBrowser/#/R-DDI-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Dictyostelium discoideum 2288 R-DME-192036 https://reactome.org/PathwayBrowser/#/R-DME-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Drosophila melanogaster 2288 R-DME-192067 https://reactome.org/PathwayBrowser/#/R-DME-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Drosophila melanogaster 2288 R-GGA-192067 https://reactome.org/PathwayBrowser/#/R-GGA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Gallus gallus 2288 R-HSA-192036 https://reactome.org/PathwayBrowser/#/R-HSA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol TAS Homo sapiens 2288 R-HSA-192067 https://reactome.org/PathwayBrowser/#/R-HSA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one TAS Homo sapiens 2288 R-MMU-192036 https://reactome.org/PathwayBrowser/#/R-MMU-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Mus musculus 2288 R-MMU-192067 https://reactome.org/PathwayBrowser/#/R-MMU-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Mus musculus 2288 R-RNO-192036 https://reactome.org/PathwayBrowser/#/R-RNO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Rattus norvegicus 2288 R-RNO-192067 https://reactome.org/PathwayBrowser/#/R-RNO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Rattus norvegicus 2288 R-SCE-192036 https://reactome.org/PathwayBrowser/#/R-SCE-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Saccharomyces cerevisiae 2288 R-SCE-192067 https://reactome.org/PathwayBrowser/#/R-SCE-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Saccharomyces cerevisiae 2288 R-SPO-192036 https://reactome.org/PathwayBrowser/#/R-SPO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Schizosaccharomyces pombe 2288 R-SPO-192067 https://reactome.org/PathwayBrowser/#/R-SPO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Schizosaccharomyces pombe 2288 R-SSC-192036 https://reactome.org/PathwayBrowser/#/R-SSC-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Sus scrofa 2288 R-SSC-192067 https://reactome.org/PathwayBrowser/#/R-SSC-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Sus scrofa 2288 R-XTR-192036 https://reactome.org/PathwayBrowser/#/R-XTR-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Xenopus tropicalis 2288 R-XTR-192067 https://reactome.org/PathwayBrowser/#/R-XTR-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Xenopus tropicalis 2290 R-BTA-192033 https://reactome.org/PathwayBrowser/#/R-BTA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Bos taurus 2290 R-BTA-192160 https://reactome.org/PathwayBrowser/#/R-BTA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Bos taurus 2290 R-CEL-192033 https://reactome.org/PathwayBrowser/#/R-CEL-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Caenorhabditis elegans 2290 R-CEL-192160 https://reactome.org/PathwayBrowser/#/R-CEL-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Caenorhabditis elegans 2290 R-CFA-192033 https://reactome.org/PathwayBrowser/#/R-CFA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Canis familiaris 2290 R-DDI-192033 https://reactome.org/PathwayBrowser/#/R-DDI-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Dictyostelium discoideum 2290 R-DDI-192160 https://reactome.org/PathwayBrowser/#/R-DDI-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Dictyostelium discoideum 2290 R-DME-192033 https://reactome.org/PathwayBrowser/#/R-DME-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Drosophila melanogaster 2290 R-DME-192160 https://reactome.org/PathwayBrowser/#/R-DME-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Drosophila melanogaster 2290 R-GGA-192033 https://reactome.org/PathwayBrowser/#/R-GGA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Gallus gallus 2290 R-HSA-192033 https://reactome.org/PathwayBrowser/#/R-HSA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one TAS Homo sapiens 2290 R-HSA-192160 https://reactome.org/PathwayBrowser/#/R-HSA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol TAS Homo sapiens 2290 R-MMU-192033 https://reactome.org/PathwayBrowser/#/R-MMU-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Mus musculus 2290 R-MMU-192160 https://reactome.org/PathwayBrowser/#/R-MMU-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Mus musculus 2290 R-RNO-192033 https://reactome.org/PathwayBrowser/#/R-RNO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Rattus norvegicus 2290 R-RNO-192160 https://reactome.org/PathwayBrowser/#/R-RNO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Rattus norvegicus 2290 R-SCE-192033 https://reactome.org/PathwayBrowser/#/R-SCE-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Saccharomyces cerevisiae 2290 R-SCE-192160 https://reactome.org/PathwayBrowser/#/R-SCE-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Saccharomyces cerevisiae 2290 R-SPO-192033 https://reactome.org/PathwayBrowser/#/R-SPO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Schizosaccharomyces pombe 2290 R-SPO-192160 https://reactome.org/PathwayBrowser/#/R-SPO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Schizosaccharomyces pombe 2290 R-SSC-192033 https://reactome.org/PathwayBrowser/#/R-SSC-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Sus scrofa 2290 R-SSC-192160 https://reactome.org/PathwayBrowser/#/R-SSC-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Sus scrofa 2290 R-XTR-192033 https://reactome.org/PathwayBrowser/#/R-XTR-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Xenopus tropicalis 2290 R-XTR-192160 https://reactome.org/PathwayBrowser/#/R-XTR-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Xenopus tropicalis 229639 R-BTA-9011595 https://reactome.org/PathwayBrowser/#/R-BTA-9011595 GSTZ1 dimer dehalogenates DCA IEA Bos taurus 229639 R-CEL-9011595 https://reactome.org/PathwayBrowser/#/R-CEL-9011595 GSTZ1 dimer dehalogenates DCA IEA Caenorhabditis elegans 229639 R-CFA-9011595 https://reactome.org/PathwayBrowser/#/R-CFA-9011595 GSTZ1 dimer dehalogenates DCA IEA Canis familiaris 229639 R-DDI-9011595 https://reactome.org/PathwayBrowser/#/R-DDI-9011595 GSTZ1 dimer dehalogenates DCA IEA Dictyostelium discoideum 229639 R-DME-9011595 https://reactome.org/PathwayBrowser/#/R-DME-9011595 GSTZ1 dimer dehalogenates DCA IEA Drosophila melanogaster 229639 R-DRE-9011595 https://reactome.org/PathwayBrowser/#/R-DRE-9011595 GSTZ1 dimer dehalogenates DCA IEA Danio rerio 229639 R-GGA-9011595 https://reactome.org/PathwayBrowser/#/R-GGA-9011595 GSTZ1 dimer dehalogenates DCA IEA Gallus gallus 229639 R-HSA-9011595 https://reactome.org/PathwayBrowser/#/R-HSA-9011595 GSTZ1 dimer dehalogenates DCA TAS Homo sapiens 229639 R-HSA-9863531 https://reactome.org/PathwayBrowser/#/R-HSA-9863531 GS-MCA spontaneously hydrolyzes TAS Homo sapiens 229639 R-MMU-9011595 https://reactome.org/PathwayBrowser/#/R-MMU-9011595 GSTZ1 dimer dehalogenates DCA IEA Mus musculus 229639 R-RNO-9011595 https://reactome.org/PathwayBrowser/#/R-RNO-9011595 GSTZ1 dimer dehalogenates DCA IEA Rattus norvegicus 229639 R-SSC-9011595 https://reactome.org/PathwayBrowser/#/R-SSC-9011595 GSTZ1 dimer dehalogenates DCA IEA Sus scrofa 229639 R-XTR-9011595 https://reactome.org/PathwayBrowser/#/R-XTR-9011595 GSTZ1 dimer dehalogenates DCA IEA Xenopus tropicalis 2332 R-BTA-9750546 https://reactome.org/PathwayBrowser/#/R-BTA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 2332 R-BTA-9750617 https://reactome.org/PathwayBrowser/#/R-BTA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 2332 R-CEL-9750546 https://reactome.org/PathwayBrowser/#/R-CEL-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 2332 R-CEL-9750617 https://reactome.org/PathwayBrowser/#/R-CEL-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 2332 R-CFA-9750546 https://reactome.org/PathwayBrowser/#/R-CFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 2332 R-CFA-9750617 https://reactome.org/PathwayBrowser/#/R-CFA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 2332 R-DDI-9750546 https://reactome.org/PathwayBrowser/#/R-DDI-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Dictyostelium discoideum 2332 R-DME-9750546 https://reactome.org/PathwayBrowser/#/R-DME-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Drosophila melanogaster 2332 R-DRE-9750546 https://reactome.org/PathwayBrowser/#/R-DRE-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 2332 R-DRE-9750617 https://reactome.org/PathwayBrowser/#/R-DRE-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 2332 R-GGA-9750546 https://reactome.org/PathwayBrowser/#/R-GGA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 2332 R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 2332 R-HSA-9750546 https://reactome.org/PathwayBrowser/#/R-HSA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 2332 R-HSA-9750617 https://reactome.org/PathwayBrowser/#/R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 2332 R-MMU-9750546 https://reactome.org/PathwayBrowser/#/R-MMU-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 2332 R-MMU-9750617 https://reactome.org/PathwayBrowser/#/R-MMU-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 2332 R-PFA-9750546 https://reactome.org/PathwayBrowser/#/R-PFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Plasmodium falciparum 2332 R-RNO-9750546 https://reactome.org/PathwayBrowser/#/R-RNO-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 2332 R-RNO-9750617 https://reactome.org/PathwayBrowser/#/R-RNO-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 2332 R-SSC-9750546 https://reactome.org/PathwayBrowser/#/R-SSC-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 2332 R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 2332 R-XTR-9750617 https://reactome.org/PathwayBrowser/#/R-XTR-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Xenopus tropicalis 23359 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 23359 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 23359 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 23359 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 23359 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 23359 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 23359 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 23359 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 23359 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 23359 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 23359 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 23359 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 23359 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 23359 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 23359 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 23359 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 23359 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 23359 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 23359 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 23359 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 23359 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 23359 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 23359 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 23359 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 23359 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 23359 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 23359 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 23359 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 23359 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 23359 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 23359 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 23359 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 23359 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 23359 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 23359 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 23359 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 23359 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 23359 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 23359 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 23359 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 23359 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 23359 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 23367 R-BTA-1006143 https://reactome.org/PathwayBrowser/#/R-BTA-1006143 CD46 binds C3b IEA Bos taurus 23367 R-BTA-1006169 https://reactome.org/PathwayBrowser/#/R-BTA-1006169 Factor H binds host cell surface markers IEA Bos taurus 23367 R-BTA-1222685 https://reactome.org/PathwayBrowser/#/R-BTA-1222685 Cathelicidin LL-37 binds to bacterial cell wall IEA Bos taurus 23367 R-BTA-1236956 https://reactome.org/PathwayBrowser/#/R-BTA-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Bos taurus 23367 R-BTA-1236958 https://reactome.org/PathwayBrowser/#/R-BTA-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Bos taurus 23367 R-BTA-1638803 https://reactome.org/PathwayBrowser/#/R-BTA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Bos taurus 23367 R-BTA-1638821 https://reactome.org/PathwayBrowser/#/R-BTA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Bos taurus 23367 R-BTA-164651 https://reactome.org/PathwayBrowser/#/R-BTA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Bos taurus 23367 R-BTA-166721 https://reactome.org/PathwayBrowser/#/R-BTA-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa IEA Bos taurus 23367 R-BTA-166726 https://reactome.org/PathwayBrowser/#/R-BTA-166726 Activation of MASPs IEA Bos taurus 23367 R-BTA-166753 https://reactome.org/PathwayBrowser/#/R-BTA-166753 Conversion of C4 into C4a and C4b IEA Bos taurus 23367 R-BTA-166792 https://reactome.org/PathwayBrowser/#/R-BTA-166792 Conversion of C2 into C2a and C2b IEA Bos taurus 23367 R-BTA-166795 https://reactome.org/PathwayBrowser/#/R-BTA-166795 Formation of Classical C3 convertase (C4b:C2a complex) IEA Bos taurus 23367 R-BTA-166817 https://reactome.org/PathwayBrowser/#/R-BTA-166817 Cleavage of C3 by C3 convertases IEA Bos taurus 23367 R-BTA-168947 https://reactome.org/PathwayBrowser/#/R-BTA-168947 Ligand binds to TLR10 IEA Bos taurus 23367 R-BTA-173636 https://reactome.org/PathwayBrowser/#/R-BTA-173636 Formation of classic pathway C5 convertase IEA Bos taurus 23367 R-BTA-173680 https://reactome.org/PathwayBrowser/#/R-BTA-173680 Activation of C5 IEA Bos taurus 23367 R-BTA-173754 https://reactome.org/PathwayBrowser/#/R-BTA-173754 Properdin stabilizes C3b:Bb bound to cell surfaces IEA Bos taurus 23367 R-BTA-174456 https://reactome.org/PathwayBrowser/#/R-BTA-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Bos taurus 23367 R-BTA-174551 https://reactome.org/PathwayBrowser/#/R-BTA-174551 Formation of alternative pathway C5 convertase IEA Bos taurus 23367 R-BTA-176700 https://reactome.org/PathwayBrowser/#/R-BTA-176700 Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure IEA Bos taurus 23367 R-BTA-176702 https://reactome.org/PathwayBrowser/#/R-BTA-176702 Disassociation of Processive Complex and Completed Telomere End IEA Bos taurus 23367 R-BTA-181450 https://reactome.org/PathwayBrowser/#/R-BTA-181450 Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure IEA Bos taurus 23367 R-BTA-183122 https://reactome.org/PathwayBrowser/#/R-BTA-183122 Factor D cleaves C3b-bound Factor B IEA Bos taurus 23367 R-BTA-183126 https://reactome.org/PathwayBrowser/#/R-BTA-183126 Factor B binds to surface-associated C3b IEA Bos taurus 23367 R-BTA-203156 https://reactome.org/PathwayBrowser/#/R-BTA-203156 Platelet-derived TREM-1 ligand binds to TREM-1 IEA Bos taurus 23367 R-BTA-2130706 https://reactome.org/PathwayBrowser/#/R-BTA-2130706 MHC class II antigen processing IEA Bos taurus 23367 R-BTA-2213240 https://reactome.org/PathwayBrowser/#/R-BTA-2213240 Reduction of disulphide bonds in MHC II antigens IEA Bos taurus 23367 R-BTA-2408524 https://reactome.org/PathwayBrowser/#/R-BTA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Bos taurus 23367 R-BTA-2466068 https://reactome.org/PathwayBrowser/#/R-BTA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Bos taurus 23367 R-BTA-2467794 https://reactome.org/PathwayBrowser/#/R-BTA-2467794 Resolution of sister chromatids IEA Bos taurus 23367 R-BTA-2467809 https://reactome.org/PathwayBrowser/#/R-BTA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Bos taurus 23367 R-BTA-2467811 https://reactome.org/PathwayBrowser/#/R-BTA-2467811 Separation of sister chromatids IEA Bos taurus 23367 R-BTA-2468039 https://reactome.org/PathwayBrowser/#/R-BTA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Bos taurus 23367 R-BTA-2468041 https://reactome.org/PathwayBrowser/#/R-BTA-2468041 CDCA5 (Sororin) enables cohesion of sister chromosomal arms IEA Bos taurus 23367 R-BTA-2468287 https://reactome.org/PathwayBrowser/#/R-BTA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Bos taurus 23367 R-BTA-2468293 https://reactome.org/PathwayBrowser/#/R-BTA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Bos taurus 23367 R-BTA-2470935 https://reactome.org/PathwayBrowser/#/R-BTA-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Bos taurus 23367 R-BTA-2473151 https://reactome.org/PathwayBrowser/#/R-BTA-2473151 CDCA5 (Sororin) enables cohesion of sister centromeres IEA Bos taurus 23367 R-BTA-2473152 https://reactome.org/PathwayBrowser/#/R-BTA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Bos taurus 23367 R-BTA-2484822 https://reactome.org/PathwayBrowser/#/R-BTA-2484822 Kinetochore assembly IEA Bos taurus 23367 R-BTA-2993898 https://reactome.org/PathwayBrowser/#/R-BTA-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Bos taurus 23367 R-BTA-2995376 https://reactome.org/PathwayBrowser/#/R-BTA-2995376 BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins IEA Bos taurus 23367 R-BTA-3785711 https://reactome.org/PathwayBrowser/#/R-BTA-3785711 Telomere shortening during replicative exhaustion IEA Bos taurus 23367 R-BTA-5324632 https://reactome.org/PathwayBrowser/#/R-BTA-5324632 Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates IEA Bos taurus 23367 R-BTA-5419261 https://reactome.org/PathwayBrowser/#/R-BTA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Bos taurus 23367 R-BTA-5419264 https://reactome.org/PathwayBrowser/#/R-BTA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Bos taurus 23367 R-BTA-5419271 https://reactome.org/PathwayBrowser/#/R-BTA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Bos taurus 23367 R-BTA-5432422 https://reactome.org/PathwayBrowser/#/R-BTA-5432422 Translocation of 55S ribosome by 3 bases in the 3' direction TAS Bos taurus 23367 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 23367 R-BTA-5617816 https://reactome.org/PathwayBrowser/#/R-BTA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Bos taurus 23367 R-BTA-5638009 https://reactome.org/PathwayBrowser/#/R-BTA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Bos taurus 23367 R-BTA-5638014 https://reactome.org/PathwayBrowser/#/R-BTA-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Bos taurus 23367 R-BTA-5693620 https://reactome.org/PathwayBrowser/#/R-BTA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Bos taurus 23367 R-BTA-6789031 https://reactome.org/PathwayBrowser/#/R-BTA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 23367 R-BTA-6789136 https://reactome.org/PathwayBrowser/#/R-BTA-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Bos taurus 23367 R-BTA-6801762 https://reactome.org/PathwayBrowser/#/R-BTA-6801762 REG3A oligomerize to form a pore complex IEA Bos taurus 23367 R-BTA-6801776 https://reactome.org/PathwayBrowser/#/R-BTA-6801776 REG3A binds bacterial phospholipids IEA Bos taurus 23367 R-BTA-6806732 https://reactome.org/PathwayBrowser/#/R-BTA-6806732 GNLY binds the bacterial cell surface IEA Bos taurus 23367 R-BTA-6807144 https://reactome.org/PathwayBrowser/#/R-BTA-6807144 HTN1,HTN3 or HTN5 binds the bacterial anionic surface IEA Bos taurus 23367 R-BTA-6807578 https://reactome.org/PathwayBrowser/#/R-BTA-6807578 GNLY binds the bacterial cell surface in the phagosome IEA Bos taurus 23367 R-BTA-6808566 https://reactome.org/PathwayBrowser/#/R-BTA-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Bos taurus 23367 R-BTA-6809521 https://reactome.org/PathwayBrowser/#/R-BTA-6809521 BPIF binds bacteria IEA Bos taurus 23367 R-BTA-6810643 https://reactome.org/PathwayBrowser/#/R-BTA-6810643 EPPIN protein complex binds bacteria IEA Bos taurus 23367 R-BTA-6810937 https://reactome.org/PathwayBrowser/#/R-BTA-6810937 Lamellar bodies bind the early cornified envelope IEA Bos taurus 23367 R-BTA-6813626 https://reactome.org/PathwayBrowser/#/R-BTA-6813626 LEAP2 binds bacteria IEA Bos taurus 23367 R-BTA-6813659 https://reactome.org/PathwayBrowser/#/R-BTA-6813659 ELANE, CTSG or PRTN3 binds bacteria IEA Bos taurus 23367 R-BTA-6814187 https://reactome.org/PathwayBrowser/#/R-BTA-6814187 EVL:PPL heterodimer binds the inner surface of the plasma membrane IEA Bos taurus 23367 R-BTA-6814387 https://reactome.org/PathwayBrowser/#/R-BTA-6814387 CASP14 cleaves filaggrin IEA Bos taurus 23367 R-BTA-6814734 https://reactome.org/PathwayBrowser/#/R-BTA-6814734 CDSN binds the cornified envelope IEA Bos taurus 23367 R-BTA-6814764 https://reactome.org/PathwayBrowser/#/R-BTA-6814764 Plasma membrane resorption IEA Bos taurus 23367 R-BTA-77592 https://reactome.org/PathwayBrowser/#/R-BTA-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Bos taurus 23367 R-BTA-8851436 https://reactome.org/PathwayBrowser/#/R-BTA-8851436 CFHR dimers bind C3b IEA Bos taurus 23367 R-BTA-8851979 https://reactome.org/PathwayBrowser/#/R-BTA-8851979 BTNL9 binds immune cell surfaces IEA Bos taurus 23367 R-BTA-8851988 https://reactome.org/PathwayBrowser/#/R-BTA-8851988 BTN2A2 binds T cell surface IEA Bos taurus 23367 R-BTA-8852010 https://reactome.org/PathwayBrowser/#/R-BTA-8852010 BTNL2 binds activated T cells surface IEA Bos taurus 23367 R-BTA-8852509 https://reactome.org/PathwayBrowser/#/R-BTA-8852509 CL-LK binds carbohydrates on target cell surface IEA Bos taurus 23367 R-BTA-8862771 https://reactome.org/PathwayBrowser/#/R-BTA-8862771 PLA2G2A binds bacterial phospholipids IEA Bos taurus 23367 R-BTA-8948027 https://reactome.org/PathwayBrowser/#/R-BTA-8948027 RNASEs bind bacterial phospholipids IEA Bos taurus 23367 R-BTA-8951486 https://reactome.org/PathwayBrowser/#/R-BTA-8951486 CD46 binds C4b IEA Bos taurus 23367 R-BTA-9615901 https://reactome.org/PathwayBrowser/#/R-BTA-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Bos taurus 23367 R-BTA-9618378 https://reactome.org/PathwayBrowser/#/R-BTA-9618378 POM121 binds the Nup107-Nup160 complex IEA Bos taurus 23367 R-BTA-9624876 https://reactome.org/PathwayBrowser/#/R-BTA-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Bos taurus 23367 R-BTA-9624893 https://reactome.org/PathwayBrowser/#/R-BTA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Bos taurus 23367 R-BTA-9629195 https://reactome.org/PathwayBrowser/#/R-BTA-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Bos taurus 23367 R-BTA-9629216 https://reactome.org/PathwayBrowser/#/R-BTA-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Bos taurus 23367 R-BTA-9634169 https://reactome.org/PathwayBrowser/#/R-BTA-9634169 POM121 and NDC1 bind the Nup93 complex IEA Bos taurus 23367 R-BTA-9670114 https://reactome.org/PathwayBrowser/#/R-BTA-9670114 Histone H3.3 deposition at telomere IEA Bos taurus 23367 R-BTA-977359 https://reactome.org/PathwayBrowser/#/R-BTA-977359 Complement factor I binds to membrane-associated Factor H:C3b IEA Bos taurus 23367 R-BTA-977363 https://reactome.org/PathwayBrowser/#/R-BTA-977363 Factor H binds to C3bBb IEA Bos taurus 23367 R-BTA-977371 https://reactome.org/PathwayBrowser/#/R-BTA-977371 Factor I inactivates Factor H-boundC3b IEA Bos taurus 23367 R-BTA-977602 https://reactome.org/PathwayBrowser/#/R-BTA-977602 Complement factor I binds to MCP, CR1:C4b, C3b IEA Bos taurus 23367 R-BTA-977605 https://reactome.org/PathwayBrowser/#/R-BTA-977605 Factor H displaces Bb IEA Bos taurus 23367 R-BTA-977615 https://reactome.org/PathwayBrowser/#/R-BTA-977615 Factor I inactivates MCP/CR1-bound C4b/C3b IEA Bos taurus 23367 R-BTA-977619 https://reactome.org/PathwayBrowser/#/R-BTA-977619 CD55 (DAF) promotes C3bBb/C4bC2a dissociation IEA Bos taurus 23367 R-BTA-981535 https://reactome.org/PathwayBrowser/#/R-BTA-981535 CD55 (DAF) binds C3bBb, C4bC2a IEA Bos taurus 23367 R-BTA-981539 https://reactome.org/PathwayBrowser/#/R-BTA-981539 C3b binds to cell surface IEA Bos taurus 23367 R-BTA-981621 https://reactome.org/PathwayBrowser/#/R-BTA-981621 C3 convertases spontaneously dissociate IEA Bos taurus 23367 R-BTA-981713 https://reactome.org/PathwayBrowser/#/R-BTA-981713 C4b binds to cell surface IEA Bos taurus 23367 R-BTA-981728 https://reactome.org/PathwayBrowser/#/R-BTA-981728 Factor H binds to membrane-associated C3b IEA Bos taurus 23367 R-BTA-983140 https://reactome.org/PathwayBrowser/#/R-BTA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Bos taurus 23367 R-BTA-983147 https://reactome.org/PathwayBrowser/#/R-BTA-983147 Release of E3 from polyubiquitinated substrate IEA Bos taurus 23367 R-BTA-983150 https://reactome.org/PathwayBrowser/#/R-BTA-983150 Proteasomal cleavage of substrate IEA Bos taurus 23367 R-BTA-983156 https://reactome.org/PathwayBrowser/#/R-BTA-983156 Polyubiquitination of substrate IEA Bos taurus 23367 R-BTA-983157 https://reactome.org/PathwayBrowser/#/R-BTA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Bos taurus 23367 R-CEL-1236956 https://reactome.org/PathwayBrowser/#/R-CEL-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Caenorhabditis elegans 23367 R-CEL-1236958 https://reactome.org/PathwayBrowser/#/R-CEL-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Caenorhabditis elegans 23367 R-CEL-164651 https://reactome.org/PathwayBrowser/#/R-CEL-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Caenorhabditis elegans 23367 R-CEL-203973 https://reactome.org/PathwayBrowser/#/R-CEL-203973 Vesicle budding IEA Caenorhabditis elegans 23367 R-CEL-2130706 https://reactome.org/PathwayBrowser/#/R-CEL-2130706 MHC class II antigen processing IEA Caenorhabditis elegans 23367 R-CEL-2213240 https://reactome.org/PathwayBrowser/#/R-CEL-2213240 Reduction of disulphide bonds in MHC II antigens IEA Caenorhabditis elegans 23367 R-CEL-2408524 https://reactome.org/PathwayBrowser/#/R-CEL-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Caenorhabditis elegans 23367 R-CEL-2466068 https://reactome.org/PathwayBrowser/#/R-CEL-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Caenorhabditis elegans 23367 R-CEL-2468039 https://reactome.org/PathwayBrowser/#/R-CEL-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Caenorhabditis elegans 23367 R-CEL-2468293 https://reactome.org/PathwayBrowser/#/R-CEL-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Caenorhabditis elegans 23367 R-CEL-2470935 https://reactome.org/PathwayBrowser/#/R-CEL-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Caenorhabditis elegans 23367 R-CEL-2473152 https://reactome.org/PathwayBrowser/#/R-CEL-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Caenorhabditis elegans 23367 R-CEL-5324632 https://reactome.org/PathwayBrowser/#/R-CEL-5324632 Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates IEA Caenorhabditis elegans 23367 R-CEL-5419261 https://reactome.org/PathwayBrowser/#/R-CEL-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Caenorhabditis elegans 23367 R-CEL-5419264 https://reactome.org/PathwayBrowser/#/R-CEL-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Caenorhabditis elegans 23367 R-CEL-5419271 https://reactome.org/PathwayBrowser/#/R-CEL-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Caenorhabditis elegans 23367 R-CEL-5638014 https://reactome.org/PathwayBrowser/#/R-CEL-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Caenorhabditis elegans 23367 R-CEL-5694417 https://reactome.org/PathwayBrowser/#/R-CEL-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Caenorhabditis elegans 23367 R-CEL-5694522 https://reactome.org/PathwayBrowser/#/R-CEL-5694522 Inner coat assembly and cargo binding IEA Caenorhabditis elegans 23367 R-CEL-5694527 https://reactome.org/PathwayBrowser/#/R-CEL-5694527 Loss of SAR1B GTPase IEA Caenorhabditis elegans 23367 R-CEL-6789031 https://reactome.org/PathwayBrowser/#/R-CEL-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 23367 R-CEL-6789136 https://reactome.org/PathwayBrowser/#/R-CEL-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Caenorhabditis elegans 23367 R-CEL-6801762 https://reactome.org/PathwayBrowser/#/R-CEL-6801762 REG3A oligomerize to form a pore complex IEA Caenorhabditis elegans 23367 R-CEL-6801776 https://reactome.org/PathwayBrowser/#/R-CEL-6801776 REG3A binds bacterial phospholipids IEA Caenorhabditis elegans 23367 R-CEL-77592 https://reactome.org/PathwayBrowser/#/R-CEL-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Caenorhabditis elegans 23367 R-CEL-8862771 https://reactome.org/PathwayBrowser/#/R-CEL-8862771 PLA2G2A binds bacterial phospholipids IEA Caenorhabditis elegans 23367 R-CEL-9615901 https://reactome.org/PathwayBrowser/#/R-CEL-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Caenorhabditis elegans 23367 R-CEL-9624876 https://reactome.org/PathwayBrowser/#/R-CEL-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Caenorhabditis elegans 23367 R-CEL-9624893 https://reactome.org/PathwayBrowser/#/R-CEL-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Caenorhabditis elegans 23367 R-CEL-983140 https://reactome.org/PathwayBrowser/#/R-CEL-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Caenorhabditis elegans 23367 R-CEL-983147 https://reactome.org/PathwayBrowser/#/R-CEL-983147 Release of E3 from polyubiquitinated substrate IEA Caenorhabditis elegans 23367 R-CEL-983150 https://reactome.org/PathwayBrowser/#/R-CEL-983150 Proteasomal cleavage of substrate IEA Caenorhabditis elegans 23367 R-CEL-983156 https://reactome.org/PathwayBrowser/#/R-CEL-983156 Polyubiquitination of substrate IEA Caenorhabditis elegans 23367 R-CEL-983157 https://reactome.org/PathwayBrowser/#/R-CEL-983157 Interaction of E3 with substrate and E2-Ub complex IEA Caenorhabditis elegans 23367 R-CFA-1006143 https://reactome.org/PathwayBrowser/#/R-CFA-1006143 CD46 binds C3b IEA Canis familiaris 23367 R-CFA-1006169 https://reactome.org/PathwayBrowser/#/R-CFA-1006169 Factor H binds host cell surface markers IEA Canis familiaris 23367 R-CFA-1222685 https://reactome.org/PathwayBrowser/#/R-CFA-1222685 Cathelicidin LL-37 binds to bacterial cell wall IEA Canis familiaris 23367 R-CFA-1236956 https://reactome.org/PathwayBrowser/#/R-CFA-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Canis familiaris 23367 R-CFA-1236958 https://reactome.org/PathwayBrowser/#/R-CFA-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Canis familiaris 23367 R-CFA-1638803 https://reactome.org/PathwayBrowser/#/R-CFA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Canis familiaris 23367 R-CFA-1638821 https://reactome.org/PathwayBrowser/#/R-CFA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Canis familiaris 23367 R-CFA-166753 https://reactome.org/PathwayBrowser/#/R-CFA-166753 Conversion of C4 into C4a and C4b IEA Canis familiaris 23367 R-CFA-166792 https://reactome.org/PathwayBrowser/#/R-CFA-166792 Conversion of C2 into C2a and C2b IEA Canis familiaris 23367 R-CFA-166795 https://reactome.org/PathwayBrowser/#/R-CFA-166795 Formation of Classical C3 convertase (C4b:C2a complex) IEA Canis familiaris 23367 R-CFA-166817 https://reactome.org/PathwayBrowser/#/R-CFA-166817 Cleavage of C3 by C3 convertases IEA Canis familiaris 23367 R-CFA-173636 https://reactome.org/PathwayBrowser/#/R-CFA-173636 Formation of classic pathway C5 convertase IEA Canis familiaris 23367 R-CFA-173680 https://reactome.org/PathwayBrowser/#/R-CFA-173680 Activation of C5 IEA Canis familiaris 23367 R-CFA-173754 https://reactome.org/PathwayBrowser/#/R-CFA-173754 Properdin stabilizes C3b:Bb bound to cell surfaces IEA Canis familiaris 23367 R-CFA-174456 https://reactome.org/PathwayBrowser/#/R-CFA-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Canis familiaris 23367 R-CFA-174551 https://reactome.org/PathwayBrowser/#/R-CFA-174551 Formation of alternative pathway C5 convertase IEA Canis familiaris 23367 R-CFA-176702 https://reactome.org/PathwayBrowser/#/R-CFA-176702 Disassociation of Processive Complex and Completed Telomere End IEA Canis familiaris 23367 R-CFA-183122 https://reactome.org/PathwayBrowser/#/R-CFA-183122 Factor D cleaves C3b-bound Factor B IEA Canis familiaris 23367 R-CFA-183126 https://reactome.org/PathwayBrowser/#/R-CFA-183126 Factor B binds to surface-associated C3b IEA Canis familiaris 23367 R-CFA-203156 https://reactome.org/PathwayBrowser/#/R-CFA-203156 Platelet-derived TREM-1 ligand binds to TREM-1 IEA Canis familiaris 23367 R-CFA-2130706 https://reactome.org/PathwayBrowser/#/R-CFA-2130706 MHC class II antigen processing IEA Canis familiaris 23367 R-CFA-2213240 https://reactome.org/PathwayBrowser/#/R-CFA-2213240 Reduction of disulphide bonds in MHC II antigens IEA Canis familiaris 23367 R-CFA-2408524 https://reactome.org/PathwayBrowser/#/R-CFA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Canis familiaris 23367 R-CFA-2466068 https://reactome.org/PathwayBrowser/#/R-CFA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Canis familiaris 23367 R-CFA-2467794 https://reactome.org/PathwayBrowser/#/R-CFA-2467794 Resolution of sister chromatids IEA Canis familiaris 23367 R-CFA-2467809 https://reactome.org/PathwayBrowser/#/R-CFA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Canis familiaris 23367 R-CFA-2467811 https://reactome.org/PathwayBrowser/#/R-CFA-2467811 Separation of sister chromatids IEA Canis familiaris 23367 R-CFA-2468039 https://reactome.org/PathwayBrowser/#/R-CFA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Canis familiaris 23367 R-CFA-2468041 https://reactome.org/PathwayBrowser/#/R-CFA-2468041 CDCA5 (Sororin) enables cohesion of sister chromosomal arms IEA Canis familiaris 23367 R-CFA-2468287 https://reactome.org/PathwayBrowser/#/R-CFA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Canis familiaris 23367 R-CFA-2468293 https://reactome.org/PathwayBrowser/#/R-CFA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Canis familiaris 23367 R-CFA-2470935 https://reactome.org/PathwayBrowser/#/R-CFA-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Canis familiaris 23367 R-CFA-2473151 https://reactome.org/PathwayBrowser/#/R-CFA-2473151 CDCA5 (Sororin) enables cohesion of sister centromeres IEA Canis familiaris 23367 R-CFA-2473152 https://reactome.org/PathwayBrowser/#/R-CFA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Canis familiaris 23367 R-CFA-2484822 https://reactome.org/PathwayBrowser/#/R-CFA-2484822 Kinetochore assembly IEA Canis familiaris 23367 R-CFA-2993898 https://reactome.org/PathwayBrowser/#/R-CFA-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Canis familiaris 23367 R-CFA-2995376 https://reactome.org/PathwayBrowser/#/R-CFA-2995376 BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins IEA Canis familiaris 23367 R-CFA-3785711 https://reactome.org/PathwayBrowser/#/R-CFA-3785711 Telomere shortening during replicative exhaustion IEA Canis familiaris 23367 R-CFA-5419261 https://reactome.org/PathwayBrowser/#/R-CFA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Canis familiaris 23367 R-CFA-5419264 https://reactome.org/PathwayBrowser/#/R-CFA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Canis familiaris 23367 R-CFA-5419271 https://reactome.org/PathwayBrowser/#/R-CFA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Canis familiaris 23367 R-CFA-5617816 https://reactome.org/PathwayBrowser/#/R-CFA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Canis familiaris 23367 R-CFA-5638009 https://reactome.org/PathwayBrowser/#/R-CFA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Canis familiaris 23367 R-CFA-5638014 https://reactome.org/PathwayBrowser/#/R-CFA-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Canis familiaris 23367 R-CFA-5693620 https://reactome.org/PathwayBrowser/#/R-CFA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Canis familiaris 23367 R-CFA-6789031 https://reactome.org/PathwayBrowser/#/R-CFA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 23367 R-CFA-6789136 https://reactome.org/PathwayBrowser/#/R-CFA-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Canis familiaris 23367 R-CFA-6801762 https://reactome.org/PathwayBrowser/#/R-CFA-6801762 REG3A oligomerize to form a pore complex IEA Canis familiaris 23367 R-CFA-6801776 https://reactome.org/PathwayBrowser/#/R-CFA-6801776 REG3A binds bacterial phospholipids IEA Canis familiaris 23367 R-CFA-6806732 https://reactome.org/PathwayBrowser/#/R-CFA-6806732 GNLY binds the bacterial cell surface IEA Canis familiaris 23367 R-CFA-6807578 https://reactome.org/PathwayBrowser/#/R-CFA-6807578 GNLY binds the bacterial cell surface in the phagosome IEA Canis familiaris 23367 R-CFA-6808566 https://reactome.org/PathwayBrowser/#/R-CFA-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Canis familiaris 23367 R-CFA-6809521 https://reactome.org/PathwayBrowser/#/R-CFA-6809521 BPIF binds bacteria IEA Canis familiaris 23367 R-CFA-6810937 https://reactome.org/PathwayBrowser/#/R-CFA-6810937 Lamellar bodies bind the early cornified envelope IEA Canis familiaris 23367 R-CFA-6813626 https://reactome.org/PathwayBrowser/#/R-CFA-6813626 LEAP2 binds bacteria IEA Canis familiaris 23367 R-CFA-6813659 https://reactome.org/PathwayBrowser/#/R-CFA-6813659 ELANE, CTSG or PRTN3 binds bacteria IEA Canis familiaris 23367 R-CFA-6814187 https://reactome.org/PathwayBrowser/#/R-CFA-6814187 EVL:PPL heterodimer binds the inner surface of the plasma membrane IEA Canis familiaris 23367 R-CFA-6814387 https://reactome.org/PathwayBrowser/#/R-CFA-6814387 CASP14 cleaves filaggrin IEA Canis familiaris 23367 R-CFA-6814734 https://reactome.org/PathwayBrowser/#/R-CFA-6814734 CDSN binds the cornified envelope IEA Canis familiaris 23367 R-CFA-6814764 https://reactome.org/PathwayBrowser/#/R-CFA-6814764 Plasma membrane resorption IEA Canis familiaris 23367 R-CFA-77592 https://reactome.org/PathwayBrowser/#/R-CFA-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Canis familiaris 23367 R-CFA-8851436 https://reactome.org/PathwayBrowser/#/R-CFA-8851436 CFHR dimers bind C3b IEA Canis familiaris 23367 R-CFA-8851979 https://reactome.org/PathwayBrowser/#/R-CFA-8851979 BTNL9 binds immune cell surfaces IEA Canis familiaris 23367 R-CFA-8851988 https://reactome.org/PathwayBrowser/#/R-CFA-8851988 BTN2A2 binds T cell surface IEA Canis familiaris 23367 R-CFA-8852010 https://reactome.org/PathwayBrowser/#/R-CFA-8852010 BTNL2 binds activated T cells surface IEA Canis familiaris 23367 R-CFA-8852509 https://reactome.org/PathwayBrowser/#/R-CFA-8852509 CL-LK binds carbohydrates on target cell surface IEA Canis familiaris 23367 R-CFA-8951486 https://reactome.org/PathwayBrowser/#/R-CFA-8951486 CD46 binds C4b IEA Canis familiaris 23367 R-CFA-9615901 https://reactome.org/PathwayBrowser/#/R-CFA-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Canis familiaris 23367 R-CFA-9618378 https://reactome.org/PathwayBrowser/#/R-CFA-9618378 POM121 binds the Nup107-Nup160 complex IEA Canis familiaris 23367 R-CFA-9624876 https://reactome.org/PathwayBrowser/#/R-CFA-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Canis familiaris 23367 R-CFA-9624893 https://reactome.org/PathwayBrowser/#/R-CFA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Canis familiaris 23367 R-CFA-9629195 https://reactome.org/PathwayBrowser/#/R-CFA-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Canis familiaris 23367 R-CFA-9629216 https://reactome.org/PathwayBrowser/#/R-CFA-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Canis familiaris 23367 R-CFA-9634169 https://reactome.org/PathwayBrowser/#/R-CFA-9634169 POM121 and NDC1 bind the Nup93 complex IEA Canis familiaris 23367 R-CFA-9670101 https://reactome.org/PathwayBrowser/#/R-CFA-9670101 ATRX:DAXX binds to subtelomeric chromosomal regions IEA Canis familiaris 23367 R-CFA-977359 https://reactome.org/PathwayBrowser/#/R-CFA-977359 Complement factor I binds to membrane-associated Factor H:C3b IEA Canis familiaris 23367 R-CFA-977363 https://reactome.org/PathwayBrowser/#/R-CFA-977363 Factor H binds to C3bBb IEA Canis familiaris 23367 R-CFA-977371 https://reactome.org/PathwayBrowser/#/R-CFA-977371 Factor I inactivates Factor H-boundC3b IEA Canis familiaris 23367 R-CFA-977375 https://reactome.org/PathwayBrowser/#/R-CFA-977375 CR1 binds C3bBb/C4bC2a IEA Canis familiaris 23367 R-CFA-977602 https://reactome.org/PathwayBrowser/#/R-CFA-977602 Complement factor I binds to MCP, CR1:C4b, C3b IEA Canis familiaris 23367 R-CFA-977605 https://reactome.org/PathwayBrowser/#/R-CFA-977605 Factor H displaces Bb IEA Canis familiaris 23367 R-CFA-977615 https://reactome.org/PathwayBrowser/#/R-CFA-977615 Factor I inactivates MCP/CR1-bound C4b/C3b IEA Canis familiaris 23367 R-CFA-977619 https://reactome.org/PathwayBrowser/#/R-CFA-977619 CD55 (DAF) promotes C3bBb/C4bC2a dissociation IEA Canis familiaris 23367 R-CFA-977629 https://reactome.org/PathwayBrowser/#/R-CFA-977629 Displacement of C2a/Bb by CR1 IEA Canis familiaris 23367 R-CFA-981535 https://reactome.org/PathwayBrowser/#/R-CFA-981535 CD55 (DAF) binds C3bBb, C4bC2a IEA Canis familiaris 23367 R-CFA-981539 https://reactome.org/PathwayBrowser/#/R-CFA-981539 C3b binds to cell surface IEA Canis familiaris 23367 R-CFA-981621 https://reactome.org/PathwayBrowser/#/R-CFA-981621 C3 convertases spontaneously dissociate IEA Canis familiaris 23367 R-CFA-981713 https://reactome.org/PathwayBrowser/#/R-CFA-981713 C4b binds to cell surface IEA Canis familiaris 23367 R-CFA-981728 https://reactome.org/PathwayBrowser/#/R-CFA-981728 Factor H binds to membrane-associated C3b IEA Canis familiaris 23367 R-CFA-983140 https://reactome.org/PathwayBrowser/#/R-CFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Canis familiaris 23367 R-CFA-983147 https://reactome.org/PathwayBrowser/#/R-CFA-983147 Release of E3 from polyubiquitinated substrate IEA Canis familiaris 23367 R-CFA-983150 https://reactome.org/PathwayBrowser/#/R-CFA-983150 Proteasomal cleavage of substrate IEA Canis familiaris 23367 R-CFA-983156 https://reactome.org/PathwayBrowser/#/R-CFA-983156 Polyubiquitination of substrate IEA Canis familiaris 23367 R-CFA-983157 https://reactome.org/PathwayBrowser/#/R-CFA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Canis familiaris 23367 R-DDI-164651 https://reactome.org/PathwayBrowser/#/R-DDI-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Dictyostelium discoideum 23367 R-DDI-2130706 https://reactome.org/PathwayBrowser/#/R-DDI-2130706 MHC class II antigen processing IEA Dictyostelium discoideum 23367 R-DDI-2466068 https://reactome.org/PathwayBrowser/#/R-DDI-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Dictyostelium discoideum 23367 R-DDI-2468039 https://reactome.org/PathwayBrowser/#/R-DDI-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Dictyostelium discoideum 23367 R-DDI-2470935 https://reactome.org/PathwayBrowser/#/R-DDI-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Dictyostelium discoideum 23367 R-DDI-2473152 https://reactome.org/PathwayBrowser/#/R-DDI-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Dictyostelium discoideum 23367 R-DDI-5324632 https://reactome.org/PathwayBrowser/#/R-DDI-5324632 Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates IEA Dictyostelium discoideum 23367 R-DDI-6789031 https://reactome.org/PathwayBrowser/#/R-DDI-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 23367 R-DDI-6789136 https://reactome.org/PathwayBrowser/#/R-DDI-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Dictyostelium discoideum 23367 R-DDI-9624876 https://reactome.org/PathwayBrowser/#/R-DDI-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Dictyostelium discoideum 23367 R-DDI-983140 https://reactome.org/PathwayBrowser/#/R-DDI-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Dictyostelium discoideum 23367 R-DDI-983147 https://reactome.org/PathwayBrowser/#/R-DDI-983147 Release of E3 from polyubiquitinated substrate IEA Dictyostelium discoideum 23367 R-DDI-983150 https://reactome.org/PathwayBrowser/#/R-DDI-983150 Proteasomal cleavage of substrate IEA Dictyostelium discoideum 23367 R-DDI-983156 https://reactome.org/PathwayBrowser/#/R-DDI-983156 Polyubiquitination of substrate IEA Dictyostelium discoideum 23367 R-DDI-983157 https://reactome.org/PathwayBrowser/#/R-DDI-983157 Interaction of E3 with substrate and E2-Ub complex IEA Dictyostelium discoideum 23367 R-DME-1236956 https://reactome.org/PathwayBrowser/#/R-DME-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Drosophila melanogaster 23367 R-DME-1236958 https://reactome.org/PathwayBrowser/#/R-DME-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Drosophila melanogaster 23367 R-DME-164651 https://reactome.org/PathwayBrowser/#/R-DME-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Drosophila melanogaster 23367 R-DME-168947 https://reactome.org/PathwayBrowser/#/R-DME-168947 Ligand binds to TLR10 IEA Drosophila melanogaster 23367 R-DME-2130706 https://reactome.org/PathwayBrowser/#/R-DME-2130706 MHC class II antigen processing IEA Drosophila melanogaster 23367 R-DME-2213240 https://reactome.org/PathwayBrowser/#/R-DME-2213240 Reduction of disulphide bonds in MHC II antigens IEA Drosophila melanogaster 23367 R-DME-2466068 https://reactome.org/PathwayBrowser/#/R-DME-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Drosophila melanogaster 23367 R-DME-2468039 https://reactome.org/PathwayBrowser/#/R-DME-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Drosophila melanogaster 23367 R-DME-2468293 https://reactome.org/PathwayBrowser/#/R-DME-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Drosophila melanogaster 23367 R-DME-2470935 https://reactome.org/PathwayBrowser/#/R-DME-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Drosophila melanogaster 23367 R-DME-2473152 https://reactome.org/PathwayBrowser/#/R-DME-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Drosophila melanogaster 23367 R-DME-5324632 https://reactome.org/PathwayBrowser/#/R-DME-5324632 Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates IEA Drosophila melanogaster 23367 R-DME-5419261 https://reactome.org/PathwayBrowser/#/R-DME-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Drosophila melanogaster 23367 R-DME-5419264 https://reactome.org/PathwayBrowser/#/R-DME-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Drosophila melanogaster 23367 R-DME-5419271 https://reactome.org/PathwayBrowser/#/R-DME-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Drosophila melanogaster 23367 R-DME-6789031 https://reactome.org/PathwayBrowser/#/R-DME-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 23367 R-DME-6789136 https://reactome.org/PathwayBrowser/#/R-DME-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Drosophila melanogaster 23367 R-DME-6801762 https://reactome.org/PathwayBrowser/#/R-DME-6801762 REG3A oligomerize to form a pore complex IEA Drosophila melanogaster 23367 R-DME-6801776 https://reactome.org/PathwayBrowser/#/R-DME-6801776 REG3A binds bacterial phospholipids IEA Drosophila melanogaster 23367 R-DME-77592 https://reactome.org/PathwayBrowser/#/R-DME-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Drosophila melanogaster 23367 R-DME-8862771 https://reactome.org/PathwayBrowser/#/R-DME-8862771 PLA2G2A binds bacterial phospholipids IEA Drosophila melanogaster 23367 R-DME-9615901 https://reactome.org/PathwayBrowser/#/R-DME-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Drosophila melanogaster 23367 R-DME-9618378 https://reactome.org/PathwayBrowser/#/R-DME-9618378 POM121 binds the Nup107-Nup160 complex IEA Drosophila melanogaster 23367 R-DME-9624876 https://reactome.org/PathwayBrowser/#/R-DME-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Drosophila melanogaster 23367 R-DME-9624893 https://reactome.org/PathwayBrowser/#/R-DME-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Drosophila melanogaster 23367 R-DME-9634169 https://reactome.org/PathwayBrowser/#/R-DME-9634169 POM121 and NDC1 bind the Nup93 complex IEA Drosophila melanogaster 23367 R-DME-983140 https://reactome.org/PathwayBrowser/#/R-DME-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Drosophila melanogaster 23367 R-DME-983147 https://reactome.org/PathwayBrowser/#/R-DME-983147 Release of E3 from polyubiquitinated substrate IEA Drosophila melanogaster 23367 R-DME-983150 https://reactome.org/PathwayBrowser/#/R-DME-983150 Proteasomal cleavage of substrate IEA Drosophila melanogaster 23367 R-DME-983156 https://reactome.org/PathwayBrowser/#/R-DME-983156 Polyubiquitination of substrate IEA Drosophila melanogaster 23367 R-DME-983157 https://reactome.org/PathwayBrowser/#/R-DME-983157 Interaction of E3 with substrate and E2-Ub complex IEA Drosophila melanogaster 23367 R-DRE-1006169 https://reactome.org/PathwayBrowser/#/R-DRE-1006169 Factor H binds host cell surface markers IEA Danio rerio 23367 R-DRE-1236956 https://reactome.org/PathwayBrowser/#/R-DRE-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Danio rerio 23367 R-DRE-1236958 https://reactome.org/PathwayBrowser/#/R-DRE-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Danio rerio 23367 R-DRE-164651 https://reactome.org/PathwayBrowser/#/R-DRE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Danio rerio 23367 R-DRE-166817 https://reactome.org/PathwayBrowser/#/R-DRE-166817 Cleavage of C3 by C3 convertases IEA Danio rerio 23367 R-DRE-168947 https://reactome.org/PathwayBrowser/#/R-DRE-168947 Ligand binds to TLR10 IEA Danio rerio 23367 R-DRE-183122 https://reactome.org/PathwayBrowser/#/R-DRE-183122 Factor D cleaves C3b-bound Factor B IEA Danio rerio 23367 R-DRE-183126 https://reactome.org/PathwayBrowser/#/R-DRE-183126 Factor B binds to surface-associated C3b IEA Danio rerio 23367 R-DRE-2130706 https://reactome.org/PathwayBrowser/#/R-DRE-2130706 MHC class II antigen processing IEA Danio rerio 23367 R-DRE-2213240 https://reactome.org/PathwayBrowser/#/R-DRE-2213240 Reduction of disulphide bonds in MHC II antigens IEA Danio rerio 23367 R-DRE-2408524 https://reactome.org/PathwayBrowser/#/R-DRE-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Danio rerio 23367 R-DRE-2466068 https://reactome.org/PathwayBrowser/#/R-DRE-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Danio rerio 23367 R-DRE-2468039 https://reactome.org/PathwayBrowser/#/R-DRE-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Danio rerio 23367 R-DRE-2468293 https://reactome.org/PathwayBrowser/#/R-DRE-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Danio rerio 23367 R-DRE-2473152 https://reactome.org/PathwayBrowser/#/R-DRE-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Danio rerio 23367 R-DRE-5419261 https://reactome.org/PathwayBrowser/#/R-DRE-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Danio rerio 23367 R-DRE-5638014 https://reactome.org/PathwayBrowser/#/R-DRE-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Danio rerio 23367 R-DRE-6806732 https://reactome.org/PathwayBrowser/#/R-DRE-6806732 GNLY binds the bacterial cell surface IEA Danio rerio 23367 R-DRE-6807578 https://reactome.org/PathwayBrowser/#/R-DRE-6807578 GNLY binds the bacterial cell surface in the phagosome IEA Danio rerio 23367 R-DRE-6813626 https://reactome.org/PathwayBrowser/#/R-DRE-6813626 LEAP2 binds bacteria IEA Danio rerio 23367 R-DRE-8851436 https://reactome.org/PathwayBrowser/#/R-DRE-8851436 CFHR dimers bind C3b IEA Danio rerio 23367 R-DRE-8948027 https://reactome.org/PathwayBrowser/#/R-DRE-8948027 RNASEs bind bacterial phospholipids IEA Danio rerio 23367 R-DRE-9624876 https://reactome.org/PathwayBrowser/#/R-DRE-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Danio rerio 23367 R-DRE-9624893 https://reactome.org/PathwayBrowser/#/R-DRE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Danio rerio 23367 R-DRE-977363 https://reactome.org/PathwayBrowser/#/R-DRE-977363 Factor H binds to C3bBb IEA Danio rerio 23367 R-DRE-977605 https://reactome.org/PathwayBrowser/#/R-DRE-977605 Factor H displaces Bb IEA Danio rerio 23367 R-DRE-981539 https://reactome.org/PathwayBrowser/#/R-DRE-981539 C3b binds to cell surface IEA Danio rerio 23367 R-DRE-981728 https://reactome.org/PathwayBrowser/#/R-DRE-981728 Factor H binds to membrane-associated C3b IEA Danio rerio 23367 R-DRE-983140 https://reactome.org/PathwayBrowser/#/R-DRE-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Danio rerio 23367 R-DRE-983147 https://reactome.org/PathwayBrowser/#/R-DRE-983147 Release of E3 from polyubiquitinated substrate IEA Danio rerio 23367 R-DRE-983150 https://reactome.org/PathwayBrowser/#/R-DRE-983150 Proteasomal cleavage of substrate IEA Danio rerio 23367 R-DRE-983156 https://reactome.org/PathwayBrowser/#/R-DRE-983156 Polyubiquitination of substrate IEA Danio rerio 23367 R-DRE-983157 https://reactome.org/PathwayBrowser/#/R-DRE-983157 Interaction of E3 with substrate and E2-Ub complex IEA Danio rerio 23367 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 23367 R-ECO-159887 https://reactome.org/PathwayBrowser/#/R-ECO-159887 Translocation of ribosome by 3 bases in the 3' direction TAS Escherichia coli 23367 R-GGA-1006143 https://reactome.org/PathwayBrowser/#/R-GGA-1006143 CD46 binds C3b IEA Gallus gallus 23367 R-GGA-1006169 https://reactome.org/PathwayBrowser/#/R-GGA-1006169 Factor H binds host cell surface markers IEA Gallus gallus 23367 R-GGA-1222685 https://reactome.org/PathwayBrowser/#/R-GGA-1222685 Cathelicidin LL-37 binds to bacterial cell wall IEA Gallus gallus 23367 R-GGA-1236956 https://reactome.org/PathwayBrowser/#/R-GGA-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Gallus gallus 23367 R-GGA-1236958 https://reactome.org/PathwayBrowser/#/R-GGA-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Gallus gallus 23367 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus 23367 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus 23367 R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus 23367 R-GGA-166721 https://reactome.org/PathwayBrowser/#/R-GGA-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa IEA Gallus gallus 23367 R-GGA-166726 https://reactome.org/PathwayBrowser/#/R-GGA-166726 Activation of MASPs IEA Gallus gallus 23367 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus 23367 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus 23367 R-GGA-166795 https://reactome.org/PathwayBrowser/#/R-GGA-166795 Formation of Classical C3 convertase (C4b:C2a complex) IEA Gallus gallus 23367 R-GGA-166817 https://reactome.org/PathwayBrowser/#/R-GGA-166817 Cleavage of C3 by C3 convertases IEA Gallus gallus 23367 R-GGA-168947 https://reactome.org/PathwayBrowser/#/R-GGA-168947 Ligand binds to TLR10 IEA Gallus gallus 23367 R-GGA-173636 https://reactome.org/PathwayBrowser/#/R-GGA-173636 Formation of classic pathway C5 convertase IEA Gallus gallus 23367 R-GGA-173680 https://reactome.org/PathwayBrowser/#/R-GGA-173680 Activation of C5 IEA Gallus gallus 23367 R-GGA-183122 https://reactome.org/PathwayBrowser/#/R-GGA-183122 Factor D cleaves C3b-bound Factor B IEA Gallus gallus 23367 R-GGA-183126 https://reactome.org/PathwayBrowser/#/R-GGA-183126 Factor B binds to surface-associated C3b IEA Gallus gallus 23367 R-GGA-2130706 https://reactome.org/PathwayBrowser/#/R-GGA-2130706 MHC class II antigen processing IEA Gallus gallus 23367 R-GGA-2132061 https://reactome.org/PathwayBrowser/#/R-GGA-2132061 Complement factor B binds to surface-bound C3b fragment IEA Gallus gallus 23367 R-GGA-2132074 https://reactome.org/PathwayBrowser/#/R-GGA-2132074 Cleavage of surface-bound factor B IEA Gallus gallus 23367 R-GGA-2132085 https://reactome.org/PathwayBrowser/#/R-GGA-2132085 Cleavage of C3 by surface-bound C3 convertases TAS Gallus gallus 23367 R-GGA-2132096 https://reactome.org/PathwayBrowser/#/R-GGA-2132096 Formation of C4b:factor B complex IEA Gallus gallus 23367 R-GGA-2132187 https://reactome.org/PathwayBrowser/#/R-GGA-2132187 MBL or ficolin binds an oligosaccharide pattern on the target cell surface TAS Gallus gallus 23367 R-GGA-2132201 https://reactome.org/PathwayBrowser/#/R-GGA-2132201 Opsonization with C3b or C4b IEA Gallus gallus 23367 R-GGA-2132206 https://reactome.org/PathwayBrowser/#/R-GGA-2132206 MASPs activation TAS Gallus gallus 23367 R-GGA-2132210 https://reactome.org/PathwayBrowser/#/R-GGA-2132210 C3b fragment binds to the target cell surface IEA Gallus gallus 23367 R-GGA-2132222 https://reactome.org/PathwayBrowser/#/R-GGA-2132222 Cleavage of factor B to form classical C3 convertase TAS Gallus gallus 23367 R-GGA-2132233 https://reactome.org/PathwayBrowser/#/R-GGA-2132233 Proteolytic cleavage of complement factor C4 TAS Gallus gallus 23367 R-GGA-2132248 https://reactome.org/PathwayBrowser/#/R-GGA-2132248 C4b binds to target cell surface IEA Gallus gallus 23367 R-GGA-2132260 https://reactome.org/PathwayBrowser/#/R-GGA-2132260 Complement factor I inactivates surface-bound C3b IEA Gallus gallus 23367 R-GGA-2132264 https://reactome.org/PathwayBrowser/#/R-GGA-2132264 Formation of alternate C5 convertase IEA Gallus gallus 23367 R-GGA-2132269 https://reactome.org/PathwayBrowser/#/R-GGA-2132269 Formation of classical C5 convertase IEA Gallus gallus 23367 R-GGA-2132271 https://reactome.org/PathwayBrowser/#/R-GGA-2132271 Factor H displaces Bb in Cb:Bb complex IEA Gallus gallus 23367 R-GGA-2132277 https://reactome.org/PathwayBrowser/#/R-GGA-2132277 Complement factor H binds to surface-bound C3b IEA Gallus gallus 23367 R-GGA-2132278 https://reactome.org/PathwayBrowser/#/R-GGA-2132278 Cleavage of C5 by C5 convertases IEA Gallus gallus 23367 R-GGA-2132283 https://reactome.org/PathwayBrowser/#/R-GGA-2132283 Factor H binds to host cell surface IEA Gallus gallus 23367 R-GGA-2213240 https://reactome.org/PathwayBrowser/#/R-GGA-2213240 Reduction of disulphide bonds in MHC II antigens IEA Gallus gallus 23367 R-GGA-2408524 https://reactome.org/PathwayBrowser/#/R-GGA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Gallus gallus 23367 R-GGA-2466068 https://reactome.org/PathwayBrowser/#/R-GGA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Gallus gallus 23367 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus 23367 R-GGA-2468039 https://reactome.org/PathwayBrowser/#/R-GGA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus 23367 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus 23367 R-GGA-2468293 https://reactome.org/PathwayBrowser/#/R-GGA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Gallus gallus 23367 R-GGA-2470935 https://reactome.org/PathwayBrowser/#/R-GGA-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Gallus gallus 23367 R-GGA-2473152 https://reactome.org/PathwayBrowser/#/R-GGA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus 23367 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus 23367 R-GGA-2530565 https://reactome.org/PathwayBrowser/#/R-GGA-2530565 iC3b proteolysis TAS Gallus gallus 23367 R-GGA-2530573 https://reactome.org/PathwayBrowser/#/R-GGA-2530573 CREG(CR1L) binds to surface-bound C3 convertases IEA Gallus gallus 23367 R-GGA-2530584 https://reactome.org/PathwayBrowser/#/R-GGA-2530584 CREM (CREMP) binds to surface-bound C3b or C4b TAS Gallus gallus 23367 R-GGA-2530591 https://reactome.org/PathwayBrowser/#/R-GGA-2530591 CREG (CR1L) causes dissociation of C3 convertases IEA Gallus gallus 23367 R-GGA-353516 https://reactome.org/PathwayBrowser/#/R-GGA-353516 Ligation of DNA at sites of patch replacement TAS Gallus gallus 23367 R-GGA-418106 https://reactome.org/PathwayBrowser/#/R-GGA-418106 Packaging of telomere ends TAS Gallus gallus 23367 R-GGA-434053 https://reactome.org/PathwayBrowser/#/R-GGA-434053 TRAF6 binds to p-IRAK2 complexed with activated TLR IEA Gallus gallus 23367 R-GGA-434084 https://reactome.org/PathwayBrowser/#/R-GGA-434084 p-IRAK2- TRAF6 dissociates from the activated chTLR complex IEA Gallus gallus 23367 R-GGA-434130 https://reactome.org/PathwayBrowser/#/R-GGA-434130 IRAK4 binds to activated TLR5 or 15. IEA Gallus gallus 23367 R-GGA-451511 https://reactome.org/PathwayBrowser/#/R-GGA-451511 TLR15 binds to recognized ligand TAS Gallus gallus 23367 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus 23367 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus 23367 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Gallus gallus 23367 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus 23367 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus 23367 R-GGA-5638014 https://reactome.org/PathwayBrowser/#/R-GGA-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Gallus gallus 23367 R-GGA-5693620 https://reactome.org/PathwayBrowser/#/R-GGA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Gallus gallus 23367 R-GGA-6789031 https://reactome.org/PathwayBrowser/#/R-GGA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 23367 R-GGA-6789136 https://reactome.org/PathwayBrowser/#/R-GGA-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Gallus gallus 23367 R-GGA-6806732 https://reactome.org/PathwayBrowser/#/R-GGA-6806732 GNLY binds the bacterial cell surface IEA Gallus gallus 23367 R-GGA-6807578 https://reactome.org/PathwayBrowser/#/R-GGA-6807578 GNLY binds the bacterial cell surface in the phagosome IEA Gallus gallus 23367 R-GGA-6808566 https://reactome.org/PathwayBrowser/#/R-GGA-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Gallus gallus 23367 R-GGA-6809521 https://reactome.org/PathwayBrowser/#/R-GGA-6809521 BPIF binds bacteria IEA Gallus gallus 23367 R-GGA-6813626 https://reactome.org/PathwayBrowser/#/R-GGA-6813626 LEAP2 binds bacteria IEA Gallus gallus 23367 R-GGA-6813659 https://reactome.org/PathwayBrowser/#/R-GGA-6813659 ELANE, CTSG or PRTN3 binds bacteria IEA Gallus gallus 23367 R-GGA-6814187 https://reactome.org/PathwayBrowser/#/R-GGA-6814187 EVL:PPL heterodimer binds the inner surface of the plasma membrane IEA Gallus gallus 23367 R-GGA-77592 https://reactome.org/PathwayBrowser/#/R-GGA-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Gallus gallus 23367 R-GGA-8851038 https://reactome.org/PathwayBrowser/#/R-GGA-8851038 BTN3A1 binds prenylated phosphoantigens IEA Gallus gallus 23367 R-GGA-8851436 https://reactome.org/PathwayBrowser/#/R-GGA-8851436 CFHR dimers bind C3b IEA Gallus gallus 23367 R-GGA-8851979 https://reactome.org/PathwayBrowser/#/R-GGA-8851979 BTNL9 binds immune cell surfaces IEA Gallus gallus 23367 R-GGA-8851988 https://reactome.org/PathwayBrowser/#/R-GGA-8851988 BTN2A2 binds T cell surface IEA Gallus gallus 23367 R-GGA-8852010 https://reactome.org/PathwayBrowser/#/R-GGA-8852010 BTNL2 binds activated T cells surface IEA Gallus gallus 23367 R-GGA-8852013 https://reactome.org/PathwayBrowser/#/R-GGA-8852013 BTNL8 binds resting T cell surface IEA Gallus gallus 23367 R-GGA-8852509 https://reactome.org/PathwayBrowser/#/R-GGA-8852509 CL-LK binds carbohydrates on target cell surface IEA Gallus gallus 23367 R-GGA-8862771 https://reactome.org/PathwayBrowser/#/R-GGA-8862771 PLA2G2A binds bacterial phospholipids IEA Gallus gallus 23367 R-GGA-8948027 https://reactome.org/PathwayBrowser/#/R-GGA-8948027 RNASEs bind bacterial phospholipids IEA Gallus gallus 23367 R-GGA-8951486 https://reactome.org/PathwayBrowser/#/R-GGA-8951486 CD46 binds C4b IEA Gallus gallus 23367 R-GGA-9615901 https://reactome.org/PathwayBrowser/#/R-GGA-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Gallus gallus 23367 R-GGA-9618378 https://reactome.org/PathwayBrowser/#/R-GGA-9618378 POM121 binds the Nup107-Nup160 complex IEA Gallus gallus 23367 R-GGA-9624876 https://reactome.org/PathwayBrowser/#/R-GGA-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Gallus gallus 23367 R-GGA-9624893 https://reactome.org/PathwayBrowser/#/R-GGA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Gallus gallus 23367 R-GGA-9634169 https://reactome.org/PathwayBrowser/#/R-GGA-9634169 POM121 and NDC1 bind the Nup93 complex IEA Gallus gallus 23367 R-GGA-977237 https://reactome.org/PathwayBrowser/#/R-GGA-977237 IRAK2 binds to IRAK4 associated with activated TLR : MyD88 complex IEA Gallus gallus 23367 R-GGA-977238 https://reactome.org/PathwayBrowser/#/R-GGA-977238 Activated TLR5/TLR15 homodimer recruits MyD88 adaptor TAS Gallus gallus 23367 R-GGA-977239 https://reactome.org/PathwayBrowser/#/R-GGA-977239 Activated IRAK4 bound to activated TLR : MyD88 complex phosphorylates IRAK2 IEA Gallus gallus 23367 R-GGA-977250 https://reactome.org/PathwayBrowser/#/R-GGA-977250 Autophosphorylation of IRAK4 bound to activated TLR5 or 15 IEA Gallus gallus 23367 R-GGA-977359 https://reactome.org/PathwayBrowser/#/R-GGA-977359 Complement factor I binds to membrane-associated Factor H:C3b IEA Gallus gallus 23367 R-GGA-977363 https://reactome.org/PathwayBrowser/#/R-GGA-977363 Factor H binds to C3bBb IEA Gallus gallus 23367 R-GGA-977371 https://reactome.org/PathwayBrowser/#/R-GGA-977371 Factor I inactivates Factor H-boundC3b IEA Gallus gallus 23367 R-GGA-977375 https://reactome.org/PathwayBrowser/#/R-GGA-977375 CR1 binds C3bBb/C4bC2a IEA Gallus gallus 23367 R-GGA-977602 https://reactome.org/PathwayBrowser/#/R-GGA-977602 Complement factor I binds to MCP, CR1:C4b, C3b IEA Gallus gallus 23367 R-GGA-977605 https://reactome.org/PathwayBrowser/#/R-GGA-977605 Factor H displaces Bb IEA Gallus gallus 23367 R-GGA-977615 https://reactome.org/PathwayBrowser/#/R-GGA-977615 Factor I inactivates MCP/CR1-bound C4b/C3b IEA Gallus gallus 23367 R-GGA-977619 https://reactome.org/PathwayBrowser/#/R-GGA-977619 CD55 (DAF) promotes C3bBb/C4bC2a dissociation IEA Gallus gallus 23367 R-GGA-977629 https://reactome.org/PathwayBrowser/#/R-GGA-977629 Displacement of C2a/Bb by CR1 IEA Gallus gallus 23367 R-GGA-981535 https://reactome.org/PathwayBrowser/#/R-GGA-981535 CD55 (DAF) binds C3bBb, C4bC2a IEA Gallus gallus 23367 R-GGA-981539 https://reactome.org/PathwayBrowser/#/R-GGA-981539 C3b binds to cell surface IEA Gallus gallus 23367 R-GGA-981713 https://reactome.org/PathwayBrowser/#/R-GGA-981713 C4b binds to cell surface IEA Gallus gallus 23367 R-GGA-981728 https://reactome.org/PathwayBrowser/#/R-GGA-981728 Factor H binds to membrane-associated C3b IEA Gallus gallus 23367 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus 23367 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus 23367 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus 23367 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus 23367 R-HSA-1006143 https://reactome.org/PathwayBrowser/#/R-HSA-1006143 CD46 binds C3b TAS Homo sapiens 23367 R-HSA-1006169 https://reactome.org/PathwayBrowser/#/R-HSA-1006169 Factor H binds host cell surface markers TAS Homo sapiens 23367 R-HSA-1222685 https://reactome.org/PathwayBrowser/#/R-HSA-1222685 Cathelicidin LL-37 binds to bacterial cell wall TAS Homo sapiens 23367 R-HSA-1236935 https://reactome.org/PathwayBrowser/#/R-HSA-1236935 Proteasomal cleavage of substrate IEA Homo sapiens 23367 R-HSA-1236938 https://reactome.org/PathwayBrowser/#/R-HSA-1236938 Partial proteolysis of antigen in phagolysosomes TAS Homo sapiens 23367 R-HSA-1236947 https://reactome.org/PathwayBrowser/#/R-HSA-1236947 Egress of internalized antigen to the cytosol via sec61 IEA Homo sapiens 23367 R-HSA-1236956 https://reactome.org/PathwayBrowser/#/R-HSA-1236956 Engulfment of particulate antigen into phagocytic vesicle TAS Homo sapiens 23367 R-HSA-1236958 https://reactome.org/PathwayBrowser/#/R-HSA-1236958 Interaction of particulate antigens with dendritic cell receptors TAS Homo sapiens 23367 R-HSA-1236963 https://reactome.org/PathwayBrowser/#/R-HSA-1236963 Maturation of phagosome into phagolysosome TAS Homo sapiens 23367 R-HSA-1236972 https://reactome.org/PathwayBrowser/#/R-HSA-1236972 Escape of antigens from phagosome to cytosol TAS Homo sapiens 23367 R-HSA-141671 https://reactome.org/PathwayBrowser/#/R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex IEA Homo sapiens 23367 R-HSA-141673 https://reactome.org/PathwayBrowser/#/R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex IEA Homo sapiens 23367 R-HSA-141691 https://reactome.org/PathwayBrowser/#/R-HSA-141691 GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex IEA Homo sapiens 23367 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 23367 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 23367 R-HSA-1638803 https://reactome.org/PathwayBrowser/#/R-HSA-1638803 Phosphorylation of cohesin by PLK1 at centromeres TAS Homo sapiens 23367 R-HSA-1638821 https://reactome.org/PathwayBrowser/#/R-HSA-1638821 PP2A-B56 dephosphorylates centromeric cohesin TAS Homo sapiens 23367 R-HSA-164651 https://reactome.org/PathwayBrowser/#/R-HSA-164651 Electron transfer from ubiquinol to cytochrome c of complex III TAS Homo sapiens 23367 R-HSA-164943 https://reactome.org/PathwayBrowser/#/R-HSA-164943 Nef mediated activation of the T-cell receptor TAS Homo sapiens 23367 R-HSA-166721 https://reactome.org/PathwayBrowser/#/R-HSA-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa TAS Homo sapiens 23367 R-HSA-166726 https://reactome.org/PathwayBrowser/#/R-HSA-166726 Activation of MASPs TAS Homo sapiens 23367 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens 23367 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens 23367 R-HSA-166795 https://reactome.org/PathwayBrowser/#/R-HSA-166795 Formation of Classical C3 convertase (C4b:C2a complex) TAS Homo sapiens 23367 R-HSA-166817 https://reactome.org/PathwayBrowser/#/R-HSA-166817 Cleavage of C3 by C3 convertases TAS Homo sapiens 23367 R-HSA-168272 https://reactome.org/PathwayBrowser/#/R-HSA-168272 Binding of the influenza virion to the host cell TAS Homo sapiens 23367 R-HSA-168285 https://reactome.org/PathwayBrowser/#/R-HSA-168285 Clathrin-Mediated Pit Formation And Endocytosis Of The Influenza Virion TAS Homo sapiens 23367 R-HSA-168299 https://reactome.org/PathwayBrowser/#/R-HSA-168299 Ribonucleoprotein release from M1 proteins TAS Homo sapiens 23367 R-HSA-168306 https://reactome.org/PathwayBrowser/#/R-HSA-168306 Concerted hemagglutinin pore formation TAS Homo sapiens 23367 R-HSA-168312 https://reactome.org/PathwayBrowser/#/R-HSA-168312 Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane TAS Homo sapiens 23367 R-HSA-168313 https://reactome.org/PathwayBrowser/#/R-HSA-168313 Virion-associated M2 protein mediated ion infusion TAS Homo sapiens 23367 R-HSA-168324 https://reactome.org/PathwayBrowser/#/R-HSA-168324 Conformation change in hemagglutinin freeing the fusion peptide of HA2 TAS Homo sapiens 23367 R-HSA-168860 https://reactome.org/PathwayBrowser/#/R-HSA-168860 Membrane fusion TAS Homo sapiens 23367 R-HSA-168862 https://reactome.org/PathwayBrowser/#/R-HSA-168862 Association of HA into rafts TAS Homo sapiens 23367 R-HSA-168870 https://reactome.org/PathwayBrowser/#/R-HSA-168870 Neuraminidase enzymatic release from sialic acid TAS Homo sapiens 23367 R-HSA-168882 https://reactome.org/PathwayBrowser/#/R-HSA-168882 Association of NP into rafts TAS Homo sapiens 23367 R-HSA-168947 https://reactome.org/PathwayBrowser/#/R-HSA-168947 Ligand binds to TLR10 TAS Homo sapiens 23367 R-HSA-173636 https://reactome.org/PathwayBrowser/#/R-HSA-173636 Formation of classic pathway C5 convertase TAS Homo sapiens 23367 R-HSA-173680 https://reactome.org/PathwayBrowser/#/R-HSA-173680 Activation of C5 TAS Homo sapiens 23367 R-HSA-173754 https://reactome.org/PathwayBrowser/#/R-HSA-173754 Properdin stabilizes C3b:Bb bound to cell surfaces TAS Homo sapiens 23367 R-HSA-174456 https://reactome.org/PathwayBrowser/#/R-HSA-174456 Joining of adjacent Okazaki fragments of the C-strand TAS Homo sapiens 23367 R-HSA-174551 https://reactome.org/PathwayBrowser/#/R-HSA-174551 Formation of alternative pathway C5 convertase TAS Homo sapiens 23367 R-HSA-176700 https://reactome.org/PathwayBrowser/#/R-HSA-176700 Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure TAS Homo sapiens 23367 R-HSA-176702 https://reactome.org/PathwayBrowser/#/R-HSA-176702 Disassociation of Processive Complex and Completed Telomere End TAS Homo sapiens 23367 R-HSA-181450 https://reactome.org/PathwayBrowser/#/R-HSA-181450 Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure TAS Homo sapiens 23367 R-HSA-183122 https://reactome.org/PathwayBrowser/#/R-HSA-183122 Factor D cleaves C3b-bound Factor B TAS Homo sapiens 23367 R-HSA-183126 https://reactome.org/PathwayBrowser/#/R-HSA-183126 Factor B binds to surface-associated C3b TAS Homo sapiens 23367 R-HSA-195726 https://reactome.org/PathwayBrowser/#/R-HSA-195726 Association of NA into rafts TAS Homo sapiens 23367 R-HSA-195730 https://reactome.org/PathwayBrowser/#/R-HSA-195730 Transport of processed viral proteins to the cell membrane TAS Homo sapiens 23367 R-HSA-203156 https://reactome.org/PathwayBrowser/#/R-HSA-203156 Platelet-derived TREM-1 ligand binds to TREM-1 TAS Homo sapiens 23367 R-HSA-203973 https://reactome.org/PathwayBrowser/#/R-HSA-203973 Vesicle budding TAS Homo sapiens 23367 R-HSA-204008 https://reactome.org/PathwayBrowser/#/R-HSA-204008 SEC31:SEC13 and v-SNARE recruitment TAS Homo sapiens 23367 R-HSA-2130706 https://reactome.org/PathwayBrowser/#/R-HSA-2130706 MHC class II antigen processing TAS Homo sapiens 23367 R-HSA-2213240 https://reactome.org/PathwayBrowser/#/R-HSA-2213240 Reduction of disulphide bonds in MHC II antigens TAS Homo sapiens 23367 R-HSA-2294574 https://reactome.org/PathwayBrowser/#/R-HSA-2294574 Condensin II-mediated condensation of prophase chromosomes TAS Homo sapiens 23367 R-HSA-2314566 https://reactome.org/PathwayBrowser/#/R-HSA-2314566 GORASP1 phosphorylated by PLK1 and GORASP2 phosphorylated by MAPK3-3/MAPK1 are unable to promote Golgi cisternae stacking TAS Homo sapiens 23367 R-HSA-2314569 https://reactome.org/PathwayBrowser/#/R-HSA-2314569 GOLGA2 phosphorylated by CDK1 is unable to promote fusion of ER to Golgi transport vesicles with cis-Golgi TAS Homo sapiens 23367 R-HSA-2408524 https://reactome.org/PathwayBrowser/#/R-HSA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer TAS Homo sapiens 23367 R-HSA-2466068 https://reactome.org/PathwayBrowser/#/R-HSA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms TAS Homo sapiens 23367 R-HSA-2467794 https://reactome.org/PathwayBrowser/#/R-HSA-2467794 Resolution of sister chromatids TAS Homo sapiens 23367 R-HSA-2467809 https://reactome.org/PathwayBrowser/#/R-HSA-2467809 ESPL1 (Separase) cleaves centromeric cohesin TAS Homo sapiens 23367 R-HSA-2467811 https://reactome.org/PathwayBrowser/#/R-HSA-2467811 Separation of sister chromatids TAS Homo sapiens 23367 R-HSA-2468039 https://reactome.org/PathwayBrowser/#/R-HSA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 TAS Homo sapiens 23367 R-HSA-2468041 https://reactome.org/PathwayBrowser/#/R-HSA-2468041 CDCA5 (Sororin) enables cohesion of sister chromosomal arms TAS Homo sapiens 23367 R-HSA-2468287 https://reactome.org/PathwayBrowser/#/R-HSA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres TAS Homo sapiens 23367 R-HSA-2468293 https://reactome.org/PathwayBrowser/#/R-HSA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms TAS Homo sapiens 23367 R-HSA-2470935 https://reactome.org/PathwayBrowser/#/R-HSA-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 TAS Homo sapiens 23367 R-HSA-2473151 https://reactome.org/PathwayBrowser/#/R-HSA-2473151 CDCA5 (Sororin) enables cohesion of sister centromeres TAS Homo sapiens 23367 R-HSA-2473152 https://reactome.org/PathwayBrowser/#/R-HSA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 TAS Homo sapiens 23367 R-HSA-2484822 https://reactome.org/PathwayBrowser/#/R-HSA-2484822 Kinetochore assembly TAS Homo sapiens 23367 R-HSA-2520883 https://reactome.org/PathwayBrowser/#/R-HSA-2520883 Phosphorylated condensin I promotes condensation of prometaphase chromosomes TAS Homo sapiens 23367 R-HSA-2993898 https://reactome.org/PathwayBrowser/#/R-HSA-2993898 VRK1/VRK2 phosphorylate BANF1 TAS Homo sapiens 23367 R-HSA-2995376 https://reactome.org/PathwayBrowser/#/R-HSA-2995376 BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins TAS Homo sapiens 23367 R-HSA-3785711 https://reactome.org/PathwayBrowser/#/R-HSA-3785711 Telomere shortening during replicative exhaustion TAS Homo sapiens 23367 R-HSA-5324632 https://reactome.org/PathwayBrowser/#/R-HSA-5324632 Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates TAS Homo sapiens 23367 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 23367 R-HSA-5419261 https://reactome.org/PathwayBrowser/#/R-HSA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP TAS Homo sapiens 23367 R-HSA-5419264 https://reactome.org/PathwayBrowser/#/R-HSA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA TAS Homo sapiens 23367 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 23367 R-HSA-5419279 https://reactome.org/PathwayBrowser/#/R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) IEA Homo sapiens 23367 R-HSA-5602472 https://reactome.org/PathwayBrowser/#/R-HSA-5602472 Defective IRAK4 does not form a complex with MyD88 within the TLR5 complex TAS Homo sapiens 23367 R-HSA-5602603 https://reactome.org/PathwayBrowser/#/R-HSA-5602603 IRAK4 deficiency blocks formation of the MyD88-IRAK4 Myddosome in the TLR5 pathway TAS Homo sapiens 23367 R-HSA-5617816 https://reactome.org/PathwayBrowser/#/R-HSA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A TAS Homo sapiens 23367 R-HSA-5638009 https://reactome.org/PathwayBrowser/#/R-HSA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body TAS Homo sapiens 23367 R-HSA-5638014 https://reactome.org/PathwayBrowser/#/R-HSA-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP TAS Homo sapiens 23367 R-HSA-5686410 https://reactome.org/PathwayBrowser/#/R-HSA-5686410 BLM mediates dissolution of double Holliday junction TAS Homo sapiens 23367 R-HSA-5686469 https://reactome.org/PathwayBrowser/#/R-HSA-5686469 Resolution of D-loops cleaved by MUS81:EME1 or MUS81:EME2 TAS Homo sapiens 23367 R-HSA-5686483 https://reactome.org/PathwayBrowser/#/R-HSA-5686483 Resolution of Holliday junctions cleaved by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) TAS Homo sapiens 23367 R-HSA-5693589 https://reactome.org/PathwayBrowser/#/R-HSA-5693589 D-loop dissociation and strand annealing TAS Homo sapiens 23367 R-HSA-5693620 https://reactome.org/PathwayBrowser/#/R-HSA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 TAS Homo sapiens 23367 R-HSA-5694417 https://reactome.org/PathwayBrowser/#/R-HSA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 TAS Homo sapiens 23367 R-HSA-5694436 https://reactome.org/PathwayBrowser/#/R-HSA-5694436 MIA2 and MIA3 dissociate from procollagen VII vesicle TAS Homo sapiens 23367 R-HSA-5694522 https://reactome.org/PathwayBrowser/#/R-HSA-5694522 Inner coat assembly and cargo binding TAS Homo sapiens 23367 R-HSA-5694527 https://reactome.org/PathwayBrowser/#/R-HSA-5694527 Loss of SAR1B GTPase TAS Homo sapiens 23367 R-HSA-6789031 https://reactome.org/PathwayBrowser/#/R-HSA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 23367 R-HSA-6789136 https://reactome.org/PathwayBrowser/#/R-HSA-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface TAS Homo sapiens 23367 R-HSA-6801762 https://reactome.org/PathwayBrowser/#/R-HSA-6801762 REG3A oligomerize to form a pore complex TAS Homo sapiens 23367 R-HSA-6801776 https://reactome.org/PathwayBrowser/#/R-HSA-6801776 REG3A binds bacterial phospholipids TAS Homo sapiens 23367 R-HSA-6803047 https://reactome.org/PathwayBrowser/#/R-HSA-6803047 DCD peptide binds bacterial membrane phospholipids TAS Homo sapiens 23367 R-HSA-6803104 https://reactome.org/PathwayBrowser/#/R-HSA-6803104 DCD forms oligomeric complex TAS Homo sapiens 23367 R-HSA-6806732 https://reactome.org/PathwayBrowser/#/R-HSA-6806732 GNLY binds the bacterial cell surface TAS Homo sapiens 23367 R-HSA-6807144 https://reactome.org/PathwayBrowser/#/R-HSA-6807144 HTN1,HTN3 or HTN5 binds the bacterial anionic surface TAS Homo sapiens 23367 R-HSA-6807578 https://reactome.org/PathwayBrowser/#/R-HSA-6807578 GNLY binds the bacterial cell surface in the phagosome TAS Homo sapiens 23367 R-HSA-6808566 https://reactome.org/PathwayBrowser/#/R-HSA-6808566 CHGA-derived peptide binds the bacterial cell surface TAS Homo sapiens 23367 R-HSA-6809521 https://reactome.org/PathwayBrowser/#/R-HSA-6809521 BPIF binds bacteria TAS Homo sapiens 23367 R-HSA-6810643 https://reactome.org/PathwayBrowser/#/R-HSA-6810643 EPPIN protein complex binds bacteria TAS Homo sapiens 23367 R-HSA-6810894 https://reactome.org/PathwayBrowser/#/R-HSA-6810894 Envoplakin, periplakin, involucrin, SPR binding mediated by TGM1 crosslinking TAS Homo sapiens 23367 R-HSA-6810899 https://reactome.org/PathwayBrowser/#/R-HSA-6810899 TGM1 and involucrin bind the plasma membrane TAS Homo sapiens 23367 R-HSA-6810937 https://reactome.org/PathwayBrowser/#/R-HSA-6810937 Lamellar bodies bind the early cornified envelope TAS Homo sapiens 23367 R-HSA-6811539 https://reactome.org/PathwayBrowser/#/R-HSA-6811539 Reinforcement of the Cornified Envelope TAS Homo sapiens 23367 R-HSA-6813626 https://reactome.org/PathwayBrowser/#/R-HSA-6813626 LEAP2 binds bacteria TAS Homo sapiens 23367 R-HSA-6813659 https://reactome.org/PathwayBrowser/#/R-HSA-6813659 ELANE, CTSG or PRTN3 binds bacteria TAS Homo sapiens 23367 R-HSA-6814187 https://reactome.org/PathwayBrowser/#/R-HSA-6814187 EVL:PPL heterodimer binds the inner surface of the plasma membrane TAS Homo sapiens 23367 R-HSA-6814298 https://reactome.org/PathwayBrowser/#/R-HSA-6814298 Late envelope proteins bind cornified envelope:CDSN TAS Homo sapiens 23367 R-HSA-6814387 https://reactome.org/PathwayBrowser/#/R-HSA-6814387 CASP14 cleaves filaggrin TAS Homo sapiens 23367 R-HSA-6814734 https://reactome.org/PathwayBrowser/#/R-HSA-6814734 CDSN binds the cornified envelope TAS Homo sapiens 23367 R-HSA-6814764 https://reactome.org/PathwayBrowser/#/R-HSA-6814764 Plasma membrane resorption TAS Homo sapiens 23367 R-HSA-77592 https://reactome.org/PathwayBrowser/#/R-HSA-77592 Cleavage of Intronless Pre-mRNA at 3'-end TAS Homo sapiens 23367 R-HSA-8851038 https://reactome.org/PathwayBrowser/#/R-HSA-8851038 BTN3A1 binds prenylated phosphoantigens TAS Homo sapiens 23367 R-HSA-8851436 https://reactome.org/PathwayBrowser/#/R-HSA-8851436 CFHR dimers bind C3b TAS Homo sapiens 23367 R-HSA-8851979 https://reactome.org/PathwayBrowser/#/R-HSA-8851979 BTNL9 binds immune cell surfaces TAS Homo sapiens 23367 R-HSA-8851988 https://reactome.org/PathwayBrowser/#/R-HSA-8851988 BTN2A2 binds T cell surface TAS Homo sapiens 23367 R-HSA-8852010 https://reactome.org/PathwayBrowser/#/R-HSA-8852010 BTNL2 binds activated T cells surface TAS Homo sapiens 23367 R-HSA-8852013 https://reactome.org/PathwayBrowser/#/R-HSA-8852013 BTNL8 binds resting T cell surface TAS Homo sapiens 23367 R-HSA-8852509 https://reactome.org/PathwayBrowser/#/R-HSA-8852509 CL-LK binds carbohydrates on target cell surface TAS Homo sapiens 23367 R-HSA-8862771 https://reactome.org/PathwayBrowser/#/R-HSA-8862771 PLA2G2A binds bacterial phospholipids TAS Homo sapiens 23367 R-HSA-8878603 https://reactome.org/PathwayBrowser/#/R-HSA-8878603 SSC5D binds ligands IEA Homo sapiens 23367 R-HSA-8948027 https://reactome.org/PathwayBrowser/#/R-HSA-8948027 RNASEs bind bacterial phospholipids TAS Homo sapiens 23367 R-HSA-8951486 https://reactome.org/PathwayBrowser/#/R-HSA-8951486 CD46 binds C4b TAS Homo sapiens 23367 R-HSA-9020249 https://reactome.org/PathwayBrowser/#/R-HSA-9020249 Hydroperoxy reductase reduces 4(S)-Hp-17(S)-HDHA to RvD6 TAS Homo sapiens 23367 R-HSA-9020260 https://reactome.org/PathwayBrowser/#/R-HSA-9020260 Hydroperoxy reducatse reduces 7(S)-Hp-17(S)-HDHA to RvD5 TAS Homo sapiens 23367 R-HSA-9024624 https://reactome.org/PathwayBrowser/#/R-HSA-9024624 Hydroperoxy reductase reduces 4(S)-Hp-17(R)-HDHA to AT-RvD6 TAS Homo sapiens 23367 R-HSA-9024630 https://reactome.org/PathwayBrowser/#/R-HSA-9024630 Hydroperoxy reductase reduces 7(S)-Hp-17(R)-HDHA to AT-RvD5 TAS Homo sapiens 23367 R-HSA-9025007 https://reactome.org/PathwayBrowser/#/R-HSA-9025007 Hydroperoxy reductase reduces 7(S),14(S)-diHp-DHA to 7-epi-MaR1 TAS Homo sapiens 23367 R-HSA-9026001 https://reactome.org/PathwayBrowser/#/R-HSA-9026001 Hydroperoxy reductase reduces 7,17-diHp-DPAn-3 to RvD5n-3DPA TAS Homo sapiens 23367 R-HSA-9027033 https://reactome.org/PathwayBrowser/#/R-HSA-9027033 Hydroperoxy reducatase reduces 14(S)-Hp-DHA to 14(S)-HDHA TAS Homo sapiens 23367 R-HSA-912408 https://reactome.org/PathwayBrowser/#/R-HSA-912408 Telomeres cluster at the nuclear membrane IEA Homo sapiens 23367 R-HSA-9615901 https://reactome.org/PathwayBrowser/#/R-HSA-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex TAS Homo sapiens 23367 R-HSA-9618378 https://reactome.org/PathwayBrowser/#/R-HSA-9618378 POM121 binds the Nup107-Nup160 complex TAS Homo sapiens 23367 R-HSA-9624876 https://reactome.org/PathwayBrowser/#/R-HSA-9624876 RAN:GTP recruits nuclear envelope (NE) membranes TAS Homo sapiens 23367 R-HSA-9624893 https://reactome.org/PathwayBrowser/#/R-HSA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes TAS Homo sapiens 23367 R-HSA-9629195 https://reactome.org/PathwayBrowser/#/R-HSA-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA TAS Homo sapiens 23367 R-HSA-9629216 https://reactome.org/PathwayBrowser/#/R-HSA-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA TAS Homo sapiens 23367 R-HSA-9629372 https://reactome.org/PathwayBrowser/#/R-HSA-9629372 NEIL3 recognizes and binds to thymine glycol in telomeric DNA IEA Homo sapiens 23367 R-HSA-9629373 https://reactome.org/PathwayBrowser/#/R-HSA-9629373 NEIL3 recognizes and binds to spiroiminodihydantoin in telomeric DNA IEA Homo sapiens 23367 R-HSA-9629483 https://reactome.org/PathwayBrowser/#/R-HSA-9629483 NEIL3 cleaves spiroiminodihydantoin from damaged telomeric DNA IEA Homo sapiens 23367 R-HSA-9629497 https://reactome.org/PathwayBrowser/#/R-HSA-9629497 NEIL3 cleaves thymine glycol from telomeric DNA IEA Homo sapiens 23367 R-HSA-9634169 https://reactome.org/PathwayBrowser/#/R-HSA-9634169 POM121 and NDC1 bind the Nup93 complex TAS Homo sapiens 23367 R-HSA-9634219 https://reactome.org/PathwayBrowser/#/R-HSA-9634219 NUP93 recruits the Nup62 complex IEA Homo sapiens 23367 R-HSA-9664261 https://reactome.org/PathwayBrowser/#/R-HSA-9664261 Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK TAS Homo sapiens 23367 R-HSA-9664268 https://reactome.org/PathwayBrowser/#/R-HSA-9664268 Opsonized leishmania amastigote binds FCGR3 TAS Homo sapiens 23367 R-HSA-9664270 https://reactome.org/PathwayBrowser/#/R-HSA-9664270 Recruitment of PLCgamma to membrane due to FCGR3A effect TAS Homo sapiens 23367 R-HSA-9664271 https://reactome.org/PathwayBrowser/#/R-HSA-9664271 Release of PLCG from FCGR3A TAS Homo sapiens 23367 R-HSA-9664273 https://reactome.org/PathwayBrowser/#/R-HSA-9664273 SYK binds IgG:Lma antigens:FCGR3A:p-CD3 dimers TAS Homo sapiens 23367 R-HSA-9664275 https://reactome.org/PathwayBrowser/#/R-HSA-9664275 Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers TAS Homo sapiens 23367 R-HSA-9664278 https://reactome.org/PathwayBrowser/#/R-HSA-9664278 Phosphorylation and activation of PLCG due to FCGR3A effect TAS Homo sapiens 23367 R-HSA-9664285 https://reactome.org/PathwayBrowser/#/R-HSA-9664285 IgG binds the surface of the amastigote form of Leishmania TAS Homo sapiens 23367 R-HSA-9664406 https://reactome.org/PathwayBrowser/#/R-HSA-9664406 IgG:Lma antigens binds FCGR3A:CD3 dimers TAS Homo sapiens 23367 R-HSA-9666425 https://reactome.org/PathwayBrowser/#/R-HSA-9666425 p-6Y-SYK phosphorylates VAV1,2,3 TAS Homo sapiens 23367 R-HSA-9666426 https://reactome.org/PathwayBrowser/#/R-HSA-9666426 CRKII:DOCK180:ELMO binds FCGR3A TAS Homo sapiens 23367 R-HSA-9666428 https://reactome.org/PathwayBrowser/#/R-HSA-9666428 DOCK180 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens 23367 R-HSA-9666430 https://reactome.org/PathwayBrowser/#/R-HSA-9666430 p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens 23367 R-HSA-9666433 https://reactome.org/PathwayBrowser/#/R-HSA-9666433 IgG binds the surface of the amastigote form of Leishmania TAS Homo sapiens 23367 R-HSA-9666435 https://reactome.org/PathwayBrowser/#/R-HSA-9666435 VAV1,2,3:PI(3,4,5)P3 binds p-6Y-SYK TAS Homo sapiens 23367 R-HSA-9666458 https://reactome.org/PathwayBrowser/#/R-HSA-9666458 IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole TAS Homo sapiens 23367 R-HSA-9670101 https://reactome.org/PathwayBrowser/#/R-HSA-9670101 ATRX:DAXX binds to subtelomeric chromosomal regions TAS Homo sapiens 23367 R-HSA-9670114 https://reactome.org/PathwayBrowser/#/R-HSA-9670114 Histone H3.3 deposition at telomere TAS Homo sapiens 23367 R-HSA-9670149 https://reactome.org/PathwayBrowser/#/R-HSA-9670149 TERRA transcription TAS Homo sapiens 23367 R-HSA-9685956 https://reactome.org/PathwayBrowser/#/R-HSA-9685956 3a is externalized together with membrane structures TAS Homo sapiens 23367 R-HSA-9694308 https://reactome.org/PathwayBrowser/#/R-HSA-9694308 3a is externalized together with membrane structures IEA Homo sapiens 23367 R-HSA-9701199 https://reactome.org/PathwayBrowser/#/R-HSA-9701199 Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of BRCA1 in PALB2 binding TAS Homo sapiens 23367 R-HSA-9704330 https://reactome.org/PathwayBrowser/#/R-HSA-9704330 Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in BRCA1 binding TAS Homo sapiens 23367 R-HSA-9704408 https://reactome.org/PathwayBrowser/#/R-HSA-9704408 Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in binding to BRCA2/RAD51/RAD51C TAS Homo sapiens 23367 R-HSA-9709601 https://reactome.org/PathwayBrowser/#/R-HSA-9709601 Defective recruitment of BRCA2 and RAD51 due to loss of BRCA2 function in PALB2 binding TAS Homo sapiens 23367 R-HSA-975852 https://reactome.org/PathwayBrowser/#/R-HSA-975852 IRAK1/or IRAK2 binds to the activated IRAK4 :oligo MyD88:activated TLR5 or 10 complex TAS Homo sapiens 23367 R-HSA-975853 https://reactome.org/PathwayBrowser/#/R-HSA-975853 Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR TAS Homo sapiens 23367 R-HSA-975857 https://reactome.org/PathwayBrowser/#/R-HSA-975857 TRAF6 binds to hp- IRAK1 or p-IRAK2 TAS Homo sapiens 23367 R-HSA-975861 https://reactome.org/PathwayBrowser/#/R-HSA-975861 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex TAS Homo sapiens 23367 R-HSA-975865 https://reactome.org/PathwayBrowser/#/R-HSA-975865 IRAK4 autophosphorylation within the complex activated TLR:MyD88 TAS Homo sapiens 23367 R-HSA-975866 https://reactome.org/PathwayBrowser/#/R-HSA-975866 MyD88 forms a complex with the activated TLR receptor TAS Homo sapiens 23367 R-HSA-975873 https://reactome.org/PathwayBrowser/#/R-HSA-975873 IRAK4 binds to MyD88 bound to the activated TLR5 or 10 receptor TAS Homo sapiens 23367 R-HSA-975874 https://reactome.org/PathwayBrowser/#/R-HSA-975874 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex TAS Homo sapiens 23367 R-HSA-975878 https://reactome.org/PathwayBrowser/#/R-HSA-975878 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR TAS Homo sapiens 23367 R-HSA-975879 https://reactome.org/PathwayBrowser/#/R-HSA-975879 Dissociation of hp-IRAK1:TRAF6 or IRAK2:TRAF6-oligomer from the activated TLR5 or 10:oligo-Myd88:p-IRAK4 complex TAS Homo sapiens 23367 R-HSA-975880 https://reactome.org/PathwayBrowser/#/R-HSA-975880 MyD88 oligomerization within the complex of activated TLR:MyD88 TAS Homo sapiens 23367 R-HSA-977359 https://reactome.org/PathwayBrowser/#/R-HSA-977359 Complement factor I binds to membrane-associated Factor H:C3b TAS Homo sapiens 23367 R-HSA-977363 https://reactome.org/PathwayBrowser/#/R-HSA-977363 Factor H binds to C3bBb TAS Homo sapiens 23367 R-HSA-977371 https://reactome.org/PathwayBrowser/#/R-HSA-977371 Factor I inactivates Factor H-boundC3b TAS Homo sapiens 23367 R-HSA-977375 https://reactome.org/PathwayBrowser/#/R-HSA-977375 CR1 binds C3bBb/C4bC2a TAS Homo sapiens 23367 R-HSA-977602 https://reactome.org/PathwayBrowser/#/R-HSA-977602 Complement factor I binds to MCP, CR1:C4b, C3b TAS Homo sapiens 23367 R-HSA-977605 https://reactome.org/PathwayBrowser/#/R-HSA-977605 Factor H displaces Bb TAS Homo sapiens 23367 R-HSA-977615 https://reactome.org/PathwayBrowser/#/R-HSA-977615 Factor I inactivates MCP/CR1-bound C4b/C3b TAS Homo sapiens 23367 R-HSA-977619 https://reactome.org/PathwayBrowser/#/R-HSA-977619 CD55 (DAF) promotes C3bBb/C4bC2a dissociation TAS Homo sapiens 23367 R-HSA-977629 https://reactome.org/PathwayBrowser/#/R-HSA-977629 Displacement of C2a/Bb by CR1 TAS Homo sapiens 23367 R-HSA-981535 https://reactome.org/PathwayBrowser/#/R-HSA-981535 CD55 (DAF) binds C3bBb, C4bC2a TAS Homo sapiens 23367 R-HSA-981539 https://reactome.org/PathwayBrowser/#/R-HSA-981539 C3b binds to cell surface TAS Homo sapiens 23367 R-HSA-981621 https://reactome.org/PathwayBrowser/#/R-HSA-981621 C3 convertases spontaneously dissociate TAS Homo sapiens 23367 R-HSA-981648 https://reactome.org/PathwayBrowser/#/R-HSA-981648 C4b binding protein binds C4bC2a TAS Homo sapiens 23367 R-HSA-981680 https://reactome.org/PathwayBrowser/#/R-HSA-981680 C4b binding protein displaces C2a TAS Homo sapiens 23367 R-HSA-981713 https://reactome.org/PathwayBrowser/#/R-HSA-981713 C4b binds to cell surface TAS Homo sapiens 23367 R-HSA-981728 https://reactome.org/PathwayBrowser/#/R-HSA-981728 Factor H binds to membrane-associated C3b TAS Homo sapiens 23367 R-HSA-983140 https://reactome.org/PathwayBrowser/#/R-HSA-983140 Transfer of Ub from E2 to substrate and release of E2 TAS Homo sapiens 23367 R-HSA-983147 https://reactome.org/PathwayBrowser/#/R-HSA-983147 Release of E3 from polyubiquitinated substrate TAS Homo sapiens 23367 R-HSA-983150 https://reactome.org/PathwayBrowser/#/R-HSA-983150 Proteasomal cleavage of substrate TAS Homo sapiens 23367 R-HSA-983156 https://reactome.org/PathwayBrowser/#/R-HSA-983156 Polyubiquitination of substrate TAS Homo sapiens 23367 R-HSA-983157 https://reactome.org/PathwayBrowser/#/R-HSA-983157 Interaction of E3 with substrate and E2-Ub complex TAS Homo sapiens 23367 R-MMU-1006143 https://reactome.org/PathwayBrowser/#/R-MMU-1006143 CD46 binds C3b IEA Mus musculus 23367 R-MMU-1222685 https://reactome.org/PathwayBrowser/#/R-MMU-1222685 Cathelicidin LL-37 binds to bacterial cell wall IEA Mus musculus 23367 R-MMU-1236956 https://reactome.org/PathwayBrowser/#/R-MMU-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Mus musculus 23367 R-MMU-1236958 https://reactome.org/PathwayBrowser/#/R-MMU-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Mus musculus 23367 R-MMU-1638803 https://reactome.org/PathwayBrowser/#/R-MMU-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Mus musculus 23367 R-MMU-1638821 https://reactome.org/PathwayBrowser/#/R-MMU-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Mus musculus 23367 R-MMU-164651 https://reactome.org/PathwayBrowser/#/R-MMU-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Mus musculus 23367 R-MMU-166721 https://reactome.org/PathwayBrowser/#/R-MMU-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa IEA Mus musculus 23367 R-MMU-166726 https://reactome.org/PathwayBrowser/#/R-MMU-166726 Activation of MASPs IEA Mus musculus 23367 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus 23367 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus 23367 R-MMU-166795 https://reactome.org/PathwayBrowser/#/R-MMU-166795 Formation of Classical C3 convertase (C4b:C2a complex) IEA Mus musculus 23367 R-MMU-166817 https://reactome.org/PathwayBrowser/#/R-MMU-166817 Cleavage of C3 by C3 convertases IEA Mus musculus 23367 R-MMU-173636 https://reactome.org/PathwayBrowser/#/R-MMU-173636 Formation of classic pathway C5 convertase IEA Mus musculus 23367 R-MMU-173680 https://reactome.org/PathwayBrowser/#/R-MMU-173680 Activation of C5 IEA Mus musculus 23367 R-MMU-173754 https://reactome.org/PathwayBrowser/#/R-MMU-173754 Properdin stabilizes C3b:Bb bound to cell surfaces IEA Mus musculus 23367 R-MMU-174456 https://reactome.org/PathwayBrowser/#/R-MMU-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Mus musculus 23367 R-MMU-174551 https://reactome.org/PathwayBrowser/#/R-MMU-174551 Formation of alternative pathway C5 convertase IEA Mus musculus 23367 R-MMU-176702 https://reactome.org/PathwayBrowser/#/R-MMU-176702 Disassociation of Processive Complex and Completed Telomere End IEA Mus musculus 23367 R-MMU-183122 https://reactome.org/PathwayBrowser/#/R-MMU-183122 Factor D cleaves C3b-bound Factor B IEA Mus musculus 23367 R-MMU-183126 https://reactome.org/PathwayBrowser/#/R-MMU-183126 Factor B binds to surface-associated C3b IEA Mus musculus 23367 R-MMU-203156 https://reactome.org/PathwayBrowser/#/R-MMU-203156 Platelet-derived TREM-1 ligand binds to TREM-1 IEA Mus musculus 23367 R-MMU-203973 https://reactome.org/PathwayBrowser/#/R-MMU-203973 Vesicle budding IEA Mus musculus 23367 R-MMU-204008 https://reactome.org/PathwayBrowser/#/R-MMU-204008 SEC31:SEC13 and v-SNARE recruitment IEA Mus musculus 23367 R-MMU-2130706 https://reactome.org/PathwayBrowser/#/R-MMU-2130706 MHC class II antigen processing IEA Mus musculus 23367 R-MMU-2213240 https://reactome.org/PathwayBrowser/#/R-MMU-2213240 Reduction of disulphide bonds in MHC II antigens IEA Mus musculus 23367 R-MMU-2408524 https://reactome.org/PathwayBrowser/#/R-MMU-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Mus musculus 23367 R-MMU-2466068 https://reactome.org/PathwayBrowser/#/R-MMU-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Mus musculus 23367 R-MMU-2467794 https://reactome.org/PathwayBrowser/#/R-MMU-2467794 Resolution of sister chromatids IEA Mus musculus 23367 R-MMU-2467809 https://reactome.org/PathwayBrowser/#/R-MMU-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Mus musculus 23367 R-MMU-2467811 https://reactome.org/PathwayBrowser/#/R-MMU-2467811 Separation of sister chromatids IEA Mus musculus 23367 R-MMU-2468039 https://reactome.org/PathwayBrowser/#/R-MMU-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Mus musculus 23367 R-MMU-2468041 https://reactome.org/PathwayBrowser/#/R-MMU-2468041 CDCA5 (Sororin) enables cohesion of sister chromosomal arms IEA Mus musculus 23367 R-MMU-2468287 https://reactome.org/PathwayBrowser/#/R-MMU-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Mus musculus 23367 R-MMU-2468293 https://reactome.org/PathwayBrowser/#/R-MMU-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Mus musculus 23367 R-MMU-2470935 https://reactome.org/PathwayBrowser/#/R-MMU-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Mus musculus 23367 R-MMU-2473151 https://reactome.org/PathwayBrowser/#/R-MMU-2473151 CDCA5 (Sororin) enables cohesion of sister centromeres IEA Mus musculus 23367 R-MMU-2473152 https://reactome.org/PathwayBrowser/#/R-MMU-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Mus musculus 23367 R-MMU-2484822 https://reactome.org/PathwayBrowser/#/R-MMU-2484822 Kinetochore assembly IEA Mus musculus 23367 R-MMU-2993898 https://reactome.org/PathwayBrowser/#/R-MMU-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Mus musculus 23367 R-MMU-2995376 https://reactome.org/PathwayBrowser/#/R-MMU-2995376 BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins IEA Mus musculus 23367 R-MMU-3785711 https://reactome.org/PathwayBrowser/#/R-MMU-3785711 Telomere shortening during replicative exhaustion IEA Mus musculus 23367 R-MMU-5324632 https://reactome.org/PathwayBrowser/#/R-MMU-5324632 Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates IEA Mus musculus 23367 R-MMU-5419261 https://reactome.org/PathwayBrowser/#/R-MMU-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Mus musculus 23367 R-MMU-5419264 https://reactome.org/PathwayBrowser/#/R-MMU-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Mus musculus 23367 R-MMU-5419271 https://reactome.org/PathwayBrowser/#/R-MMU-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Mus musculus 23367 R-MMU-5617816 https://reactome.org/PathwayBrowser/#/R-MMU-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Mus musculus 23367 R-MMU-5638009 https://reactome.org/PathwayBrowser/#/R-MMU-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Mus musculus 23367 R-MMU-5638014 https://reactome.org/PathwayBrowser/#/R-MMU-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Mus musculus 23367 R-MMU-5693620 https://reactome.org/PathwayBrowser/#/R-MMU-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Mus musculus 23367 R-MMU-5694417 https://reactome.org/PathwayBrowser/#/R-MMU-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Mus musculus 23367 R-MMU-5694436 https://reactome.org/PathwayBrowser/#/R-MMU-5694436 MIA2 and MIA3 dissociate from procollagen VII vesicle IEA Mus musculus 23367 R-MMU-5694522 https://reactome.org/PathwayBrowser/#/R-MMU-5694522 Inner coat assembly and cargo binding IEA Mus musculus 23367 R-MMU-5694527 https://reactome.org/PathwayBrowser/#/R-MMU-5694527 Loss of SAR1B GTPase IEA Mus musculus 23367 R-MMU-6789031 https://reactome.org/PathwayBrowser/#/R-MMU-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 23367 R-MMU-6789136 https://reactome.org/PathwayBrowser/#/R-MMU-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Mus musculus 23367 R-MMU-6801762 https://reactome.org/PathwayBrowser/#/R-MMU-6801762 REG3A oligomerize to form a pore complex IEA Mus musculus 23367 R-MMU-6801776 https://reactome.org/PathwayBrowser/#/R-MMU-6801776 REG3A binds bacterial phospholipids IEA Mus musculus 23367 R-MMU-6808566 https://reactome.org/PathwayBrowser/#/R-MMU-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Mus musculus 23367 R-MMU-6809521 https://reactome.org/PathwayBrowser/#/R-MMU-6809521 BPIF binds bacteria IEA Mus musculus 23367 R-MMU-6810643 https://reactome.org/PathwayBrowser/#/R-MMU-6810643 EPPIN protein complex binds bacteria IEA Mus musculus 23367 R-MMU-6810937 https://reactome.org/PathwayBrowser/#/R-MMU-6810937 Lamellar bodies bind the early cornified envelope IEA Mus musculus 23367 R-MMU-6813626 https://reactome.org/PathwayBrowser/#/R-MMU-6813626 LEAP2 binds bacteria IEA Mus musculus 23367 R-MMU-6813659 https://reactome.org/PathwayBrowser/#/R-MMU-6813659 ELANE, CTSG or PRTN3 binds bacteria IEA Mus musculus 23367 R-MMU-6814187 https://reactome.org/PathwayBrowser/#/R-MMU-6814187 EVL:PPL heterodimer binds the inner surface of the plasma membrane IEA Mus musculus 23367 R-MMU-6814387 https://reactome.org/PathwayBrowser/#/R-MMU-6814387 CASP14 cleaves filaggrin IEA Mus musculus 23367 R-MMU-6814734 https://reactome.org/PathwayBrowser/#/R-MMU-6814734 CDSN binds the cornified envelope IEA Mus musculus 23367 R-MMU-6814764 https://reactome.org/PathwayBrowser/#/R-MMU-6814764 Plasma membrane resorption IEA Mus musculus 23367 R-MMU-77592 https://reactome.org/PathwayBrowser/#/R-MMU-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Mus musculus 23367 R-MMU-8851436 https://reactome.org/PathwayBrowser/#/R-MMU-8851436 CFHR dimers bind C3b IEA Mus musculus 23367 R-MMU-8851979 https://reactome.org/PathwayBrowser/#/R-MMU-8851979 BTNL9 binds immune cell surfaces IEA Mus musculus 23367 R-MMU-8851988 https://reactome.org/PathwayBrowser/#/R-MMU-8851988 BTN2A2 binds T cell surface IEA Mus musculus 23367 R-MMU-8852010 https://reactome.org/PathwayBrowser/#/R-MMU-8852010 BTNL2 binds activated T cells surface IEA Mus musculus 23367 R-MMU-8852509 https://reactome.org/PathwayBrowser/#/R-MMU-8852509 CL-LK binds carbohydrates on target cell surface IEA Mus musculus 23367 R-MMU-8862771 https://reactome.org/PathwayBrowser/#/R-MMU-8862771 PLA2G2A binds bacterial phospholipids IEA Mus musculus 23367 R-MMU-8948027 https://reactome.org/PathwayBrowser/#/R-MMU-8948027 RNASEs bind bacterial phospholipids IEA Mus musculus 23367 R-MMU-8951486 https://reactome.org/PathwayBrowser/#/R-MMU-8951486 CD46 binds C4b IEA Mus musculus 23367 R-MMU-912355 https://reactome.org/PathwayBrowser/#/R-MMU-912355 Telomere clustering at the nuclear membrane TAS Mus musculus 23367 R-MMU-9615901 https://reactome.org/PathwayBrowser/#/R-MMU-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Mus musculus 23367 R-MMU-9618378 https://reactome.org/PathwayBrowser/#/R-MMU-9618378 POM121 binds the Nup107-Nup160 complex IEA Mus musculus 23367 R-MMU-9624876 https://reactome.org/PathwayBrowser/#/R-MMU-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Mus musculus 23367 R-MMU-9624893 https://reactome.org/PathwayBrowser/#/R-MMU-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Mus musculus 23367 R-MMU-9629195 https://reactome.org/PathwayBrowser/#/R-MMU-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Mus musculus 23367 R-MMU-9629216 https://reactome.org/PathwayBrowser/#/R-MMU-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Mus musculus 23367 R-MMU-9634169 https://reactome.org/PathwayBrowser/#/R-MMU-9634169 POM121 and NDC1 bind the Nup93 complex IEA Mus musculus 23367 R-MMU-9670101 https://reactome.org/PathwayBrowser/#/R-MMU-9670101 ATRX:DAXX binds to subtelomeric chromosomal regions IEA Mus musculus 23367 R-MMU-9670114 https://reactome.org/PathwayBrowser/#/R-MMU-9670114 Histone H3.3 deposition at telomere IEA Mus musculus 23367 R-MMU-977602 https://reactome.org/PathwayBrowser/#/R-MMU-977602 Complement factor I binds to MCP, CR1:C4b, C3b IEA Mus musculus 23367 R-MMU-977615 https://reactome.org/PathwayBrowser/#/R-MMU-977615 Factor I inactivates MCP/CR1-bound C4b/C3b IEA Mus musculus 23367 R-MMU-977619 https://reactome.org/PathwayBrowser/#/R-MMU-977619 CD55 (DAF) promotes C3bBb/C4bC2a dissociation IEA Mus musculus 23367 R-MMU-981535 https://reactome.org/PathwayBrowser/#/R-MMU-981535 CD55 (DAF) binds C3bBb, C4bC2a IEA Mus musculus 23367 R-MMU-981539 https://reactome.org/PathwayBrowser/#/R-MMU-981539 C3b binds to cell surface IEA Mus musculus 23367 R-MMU-981621 https://reactome.org/PathwayBrowser/#/R-MMU-981621 C3 convertases spontaneously dissociate IEA Mus musculus 23367 R-MMU-981713 https://reactome.org/PathwayBrowser/#/R-MMU-981713 C4b binds to cell surface IEA Mus musculus 23367 R-MMU-983140 https://reactome.org/PathwayBrowser/#/R-MMU-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Mus musculus 23367 R-MMU-983147 https://reactome.org/PathwayBrowser/#/R-MMU-983147 Release of E3 from polyubiquitinated substrate IEA Mus musculus 23367 R-MMU-983150 https://reactome.org/PathwayBrowser/#/R-MMU-983150 Proteasomal cleavage of substrate IEA Mus musculus 23367 R-MMU-983156 https://reactome.org/PathwayBrowser/#/R-MMU-983156 Polyubiquitination of substrate IEA Mus musculus 23367 R-MMU-983157 https://reactome.org/PathwayBrowser/#/R-MMU-983157 Interaction of E3 with substrate and E2-Ub complex IEA Mus musculus 23367 R-PFA-2130706 https://reactome.org/PathwayBrowser/#/R-PFA-2130706 MHC class II antigen processing IEA Plasmodium falciparum 23367 R-PFA-9624876 https://reactome.org/PathwayBrowser/#/R-PFA-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Plasmodium falciparum 23367 R-PFA-983140 https://reactome.org/PathwayBrowser/#/R-PFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Plasmodium falciparum 23367 R-PFA-983147 https://reactome.org/PathwayBrowser/#/R-PFA-983147 Release of E3 from polyubiquitinated substrate IEA Plasmodium falciparum 23367 R-PFA-983150 https://reactome.org/PathwayBrowser/#/R-PFA-983150 Proteasomal cleavage of substrate IEA Plasmodium falciparum 23367 R-PFA-983156 https://reactome.org/PathwayBrowser/#/R-PFA-983156 Polyubiquitination of substrate IEA Plasmodium falciparum 23367 R-PFA-983157 https://reactome.org/PathwayBrowser/#/R-PFA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Plasmodium falciparum 23367 R-RNO-1006143 https://reactome.org/PathwayBrowser/#/R-RNO-1006143 CD46 binds C3b IEA Rattus norvegicus 23367 R-RNO-1222685 https://reactome.org/PathwayBrowser/#/R-RNO-1222685 Cathelicidin LL-37 binds to bacterial cell wall IEA Rattus norvegicus 23367 R-RNO-1236956 https://reactome.org/PathwayBrowser/#/R-RNO-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Rattus norvegicus 23367 R-RNO-1236958 https://reactome.org/PathwayBrowser/#/R-RNO-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Rattus norvegicus 23367 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus 23367 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus 23367 R-RNO-164651 https://reactome.org/PathwayBrowser/#/R-RNO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Rattus norvegicus 23367 R-RNO-166721 https://reactome.org/PathwayBrowser/#/R-RNO-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa IEA Rattus norvegicus 23367 R-RNO-166726 https://reactome.org/PathwayBrowser/#/R-RNO-166726 Activation of MASPs IEA Rattus norvegicus 23367 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus 23367 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus 23367 R-RNO-166795 https://reactome.org/PathwayBrowser/#/R-RNO-166795 Formation of Classical C3 convertase (C4b:C2a complex) IEA Rattus norvegicus 23367 R-RNO-166817 https://reactome.org/PathwayBrowser/#/R-RNO-166817 Cleavage of C3 by C3 convertases IEA Rattus norvegicus 23367 R-RNO-168947 https://reactome.org/PathwayBrowser/#/R-RNO-168947 Ligand binds to TLR10 IEA Rattus norvegicus 23367 R-RNO-173636 https://reactome.org/PathwayBrowser/#/R-RNO-173636 Formation of classic pathway C5 convertase IEA Rattus norvegicus 23367 R-RNO-173680 https://reactome.org/PathwayBrowser/#/R-RNO-173680 Activation of C5 IEA Rattus norvegicus 23367 R-RNO-174456 https://reactome.org/PathwayBrowser/#/R-RNO-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Rattus norvegicus 23367 R-RNO-176702 https://reactome.org/PathwayBrowser/#/R-RNO-176702 Disassociation of Processive Complex and Completed Telomere End IEA Rattus norvegicus 23367 R-RNO-203156 https://reactome.org/PathwayBrowser/#/R-RNO-203156 Platelet-derived TREM-1 ligand binds to TREM-1 IEA Rattus norvegicus 23367 R-RNO-203973 https://reactome.org/PathwayBrowser/#/R-RNO-203973 Vesicle budding IEA Rattus norvegicus 23367 R-RNO-204008 https://reactome.org/PathwayBrowser/#/R-RNO-204008 SEC31:SEC13 and v-SNARE recruitment IEA Rattus norvegicus 23367 R-RNO-2130706 https://reactome.org/PathwayBrowser/#/R-RNO-2130706 MHC class II antigen processing IEA Rattus norvegicus 23367 R-RNO-2213240 https://reactome.org/PathwayBrowser/#/R-RNO-2213240 Reduction of disulphide bonds in MHC II antigens IEA Rattus norvegicus 23367 R-RNO-2408524 https://reactome.org/PathwayBrowser/#/R-RNO-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Rattus norvegicus 23367 R-RNO-2466068 https://reactome.org/PathwayBrowser/#/R-RNO-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Rattus norvegicus 23367 R-RNO-2467794 https://reactome.org/PathwayBrowser/#/R-RNO-2467794 Resolution of sister chromatids IEA Rattus norvegicus 23367 R-RNO-2467809 https://reactome.org/PathwayBrowser/#/R-RNO-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Rattus norvegicus 23367 R-RNO-2467811 https://reactome.org/PathwayBrowser/#/R-RNO-2467811 Separation of sister chromatids IEA Rattus norvegicus 23367 R-RNO-2468039 https://reactome.org/PathwayBrowser/#/R-RNO-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Rattus norvegicus 23367 R-RNO-2468041 https://reactome.org/PathwayBrowser/#/R-RNO-2468041 CDCA5 (Sororin) enables cohesion of sister chromosomal arms IEA Rattus norvegicus 23367 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus 23367 R-RNO-2468293 https://reactome.org/PathwayBrowser/#/R-RNO-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Rattus norvegicus 23367 R-RNO-2470935 https://reactome.org/PathwayBrowser/#/R-RNO-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Rattus norvegicus 23367 R-RNO-2473151 https://reactome.org/PathwayBrowser/#/R-RNO-2473151 CDCA5 (Sororin) enables cohesion of sister centromeres IEA Rattus norvegicus 23367 R-RNO-2473152 https://reactome.org/PathwayBrowser/#/R-RNO-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Rattus norvegicus 23367 R-RNO-2484822 https://reactome.org/PathwayBrowser/#/R-RNO-2484822 Kinetochore assembly IEA Rattus norvegicus 23367 R-RNO-2993898 https://reactome.org/PathwayBrowser/#/R-RNO-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Rattus norvegicus 23367 R-RNO-2995376 https://reactome.org/PathwayBrowser/#/R-RNO-2995376 BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins IEA Rattus norvegicus 23367 R-RNO-3785711 https://reactome.org/PathwayBrowser/#/R-RNO-3785711 Telomere shortening during replicative exhaustion IEA Rattus norvegicus 23367 R-RNO-5324632 https://reactome.org/PathwayBrowser/#/R-RNO-5324632 Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates IEA Rattus norvegicus 23367 R-RNO-5419261 https://reactome.org/PathwayBrowser/#/R-RNO-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Rattus norvegicus 23367 R-RNO-5419264 https://reactome.org/PathwayBrowser/#/R-RNO-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Rattus norvegicus 23367 R-RNO-5419271 https://reactome.org/PathwayBrowser/#/R-RNO-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Rattus norvegicus 23367 R-RNO-5617816 https://reactome.org/PathwayBrowser/#/R-RNO-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus 23367 R-RNO-5638009 https://reactome.org/PathwayBrowser/#/R-RNO-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Rattus norvegicus 23367 R-RNO-5638014 https://reactome.org/PathwayBrowser/#/R-RNO-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Rattus norvegicus 23367 R-RNO-5693620 https://reactome.org/PathwayBrowser/#/R-RNO-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Rattus norvegicus 23367 R-RNO-5694417 https://reactome.org/PathwayBrowser/#/R-RNO-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Rattus norvegicus 23367 R-RNO-5694436 https://reactome.org/PathwayBrowser/#/R-RNO-5694436 MIA2 and MIA3 dissociate from procollagen VII vesicle IEA Rattus norvegicus 23367 R-RNO-5694522 https://reactome.org/PathwayBrowser/#/R-RNO-5694522 Inner coat assembly and cargo binding IEA Rattus norvegicus 23367 R-RNO-5694527 https://reactome.org/PathwayBrowser/#/R-RNO-5694527 Loss of SAR1B GTPase IEA Rattus norvegicus 23367 R-RNO-6789031 https://reactome.org/PathwayBrowser/#/R-RNO-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 23367 R-RNO-6789136 https://reactome.org/PathwayBrowser/#/R-RNO-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Rattus norvegicus 23367 R-RNO-6801762 https://reactome.org/PathwayBrowser/#/R-RNO-6801762 REG3A oligomerize to form a pore complex IEA Rattus norvegicus 23367 R-RNO-6801776 https://reactome.org/PathwayBrowser/#/R-RNO-6801776 REG3A binds bacterial phospholipids IEA Rattus norvegicus 23367 R-RNO-6807144 https://reactome.org/PathwayBrowser/#/R-RNO-6807144 HTN1,HTN3 or HTN5 binds the bacterial anionic surface IEA Rattus norvegicus 23367 R-RNO-6808566 https://reactome.org/PathwayBrowser/#/R-RNO-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Rattus norvegicus 23367 R-RNO-6809521 https://reactome.org/PathwayBrowser/#/R-RNO-6809521 BPIF binds bacteria IEA Rattus norvegicus 23367 R-RNO-6810643 https://reactome.org/PathwayBrowser/#/R-RNO-6810643 EPPIN protein complex binds bacteria IEA Rattus norvegicus 23367 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus 23367 R-RNO-6813626 https://reactome.org/PathwayBrowser/#/R-RNO-6813626 LEAP2 binds bacteria IEA Rattus norvegicus 23367 R-RNO-6813659 https://reactome.org/PathwayBrowser/#/R-RNO-6813659 ELANE, CTSG or PRTN3 binds bacteria IEA Rattus norvegicus 23367 R-RNO-6814187 https://reactome.org/PathwayBrowser/#/R-RNO-6814187 EVL:PPL heterodimer binds the inner surface of the plasma membrane IEA Rattus norvegicus 23367 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus 23367 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus 23367 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus 23367 R-RNO-77592 https://reactome.org/PathwayBrowser/#/R-RNO-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Rattus norvegicus 23367 R-RNO-8851436 https://reactome.org/PathwayBrowser/#/R-RNO-8851436 CFHR dimers bind C3b IEA Rattus norvegicus 23367 R-RNO-8851979 https://reactome.org/PathwayBrowser/#/R-RNO-8851979 BTNL9 binds immune cell surfaces IEA Rattus norvegicus 23367 R-RNO-8851988 https://reactome.org/PathwayBrowser/#/R-RNO-8851988 BTN2A2 binds T cell surface IEA Rattus norvegicus 23367 R-RNO-8852010 https://reactome.org/PathwayBrowser/#/R-RNO-8852010 BTNL2 binds activated T cells surface IEA Rattus norvegicus 23367 R-RNO-8852509 https://reactome.org/PathwayBrowser/#/R-RNO-8852509 CL-LK binds carbohydrates on target cell surface IEA Rattus norvegicus 23367 R-RNO-8862771 https://reactome.org/PathwayBrowser/#/R-RNO-8862771 PLA2G2A binds bacterial phospholipids IEA Rattus norvegicus 23367 R-RNO-8948027 https://reactome.org/PathwayBrowser/#/R-RNO-8948027 RNASEs bind bacterial phospholipids IEA Rattus norvegicus 23367 R-RNO-8951486 https://reactome.org/PathwayBrowser/#/R-RNO-8951486 CD46 binds C4b IEA Rattus norvegicus 23367 R-RNO-9615901 https://reactome.org/PathwayBrowser/#/R-RNO-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Rattus norvegicus 23367 R-RNO-9618378 https://reactome.org/PathwayBrowser/#/R-RNO-9618378 POM121 binds the Nup107-Nup160 complex IEA Rattus norvegicus 23367 R-RNO-9624876 https://reactome.org/PathwayBrowser/#/R-RNO-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Rattus norvegicus 23367 R-RNO-9624893 https://reactome.org/PathwayBrowser/#/R-RNO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Rattus norvegicus 23367 R-RNO-9629195 https://reactome.org/PathwayBrowser/#/R-RNO-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Rattus norvegicus 23367 R-RNO-9629216 https://reactome.org/PathwayBrowser/#/R-RNO-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Rattus norvegicus 23367 R-RNO-9634169 https://reactome.org/PathwayBrowser/#/R-RNO-9634169 POM121 and NDC1 bind the Nup93 complex IEA Rattus norvegicus 23367 R-RNO-977375 https://reactome.org/PathwayBrowser/#/R-RNO-977375 CR1 binds C3bBb/C4bC2a IEA Rattus norvegicus 23367 R-RNO-977602 https://reactome.org/PathwayBrowser/#/R-RNO-977602 Complement factor I binds to MCP, CR1:C4b, C3b IEA Rattus norvegicus 23367 R-RNO-977615 https://reactome.org/PathwayBrowser/#/R-RNO-977615 Factor I inactivates MCP/CR1-bound C4b/C3b IEA Rattus norvegicus 23367 R-RNO-981535 https://reactome.org/PathwayBrowser/#/R-RNO-981535 CD55 (DAF) binds C3bBb, C4bC2a IEA Rattus norvegicus 23367 R-RNO-981539 https://reactome.org/PathwayBrowser/#/R-RNO-981539 C3b binds to cell surface IEA Rattus norvegicus 23367 R-RNO-981713 https://reactome.org/PathwayBrowser/#/R-RNO-981713 C4b binds to cell surface IEA Rattus norvegicus 23367 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus 23367 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus 23367 R-RNO-983150 https://reactome.org/PathwayBrowser/#/R-RNO-983150 Proteasomal cleavage of substrate IEA Rattus norvegicus 23367 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus 23367 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus 23367 R-SCE-141667 https://reactome.org/PathwayBrowser/#/R-SCE-141667 GTP bound eRF3:eRF1 complex binds the peptidyl-tRNA:mRNA:Ribosome complex TAS Saccharomyces cerevisiae 23367 R-SCE-141687 https://reactome.org/PathwayBrowser/#/R-SCE-141687 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex TAS Saccharomyces cerevisiae 23367 R-SCE-141698 https://reactome.org/PathwayBrowser/#/R-SCE-141698 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex TAS Saccharomyces cerevisiae 23367 R-SCE-164651 https://reactome.org/PathwayBrowser/#/R-SCE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Saccharomyces cerevisiae 23367 R-SCE-2466068 https://reactome.org/PathwayBrowser/#/R-SCE-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Saccharomyces cerevisiae 23367 R-SCE-2468039 https://reactome.org/PathwayBrowser/#/R-SCE-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Saccharomyces cerevisiae 23367 R-SCE-2473152 https://reactome.org/PathwayBrowser/#/R-SCE-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Saccharomyces cerevisiae 23367 R-SCE-5324632 https://reactome.org/PathwayBrowser/#/R-SCE-5324632 Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates IEA Saccharomyces cerevisiae 23367 R-SCE-5638014 https://reactome.org/PathwayBrowser/#/R-SCE-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Saccharomyces cerevisiae 23367 R-SCE-9624876 https://reactome.org/PathwayBrowser/#/R-SCE-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Saccharomyces cerevisiae 23367 R-SCE-9624893 https://reactome.org/PathwayBrowser/#/R-SCE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Saccharomyces cerevisiae 23367 R-SCE-983140 https://reactome.org/PathwayBrowser/#/R-SCE-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Saccharomyces cerevisiae 23367 R-SCE-983147 https://reactome.org/PathwayBrowser/#/R-SCE-983147 Release of E3 from polyubiquitinated substrate IEA Saccharomyces cerevisiae 23367 R-SCE-983150 https://reactome.org/PathwayBrowser/#/R-SCE-983150 Proteasomal cleavage of substrate IEA Saccharomyces cerevisiae 23367 R-SCE-983156 https://reactome.org/PathwayBrowser/#/R-SCE-983156 Polyubiquitination of substrate IEA Saccharomyces cerevisiae 23367 R-SCE-983157 https://reactome.org/PathwayBrowser/#/R-SCE-983157 Interaction of E3 with substrate and E2-Ub complex IEA Saccharomyces cerevisiae 23367 R-SPO-164651 https://reactome.org/PathwayBrowser/#/R-SPO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Schizosaccharomyces pombe 23367 R-SPO-2466068 https://reactome.org/PathwayBrowser/#/R-SPO-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Schizosaccharomyces pombe 23367 R-SPO-2470935 https://reactome.org/PathwayBrowser/#/R-SPO-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Schizosaccharomyces pombe 23367 R-SPO-5324632 https://reactome.org/PathwayBrowser/#/R-SPO-5324632 Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates IEA Schizosaccharomyces pombe 23367 R-SPO-5638014 https://reactome.org/PathwayBrowser/#/R-SPO-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Schizosaccharomyces pombe 23367 R-SPO-9618378 https://reactome.org/PathwayBrowser/#/R-SPO-9618378 POM121 binds the Nup107-Nup160 complex IEA Schizosaccharomyces pombe 23367 R-SPO-9624876 https://reactome.org/PathwayBrowser/#/R-SPO-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Schizosaccharomyces pombe 23367 R-SPO-9624893 https://reactome.org/PathwayBrowser/#/R-SPO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Schizosaccharomyces pombe 23367 R-SPO-9634169 https://reactome.org/PathwayBrowser/#/R-SPO-9634169 POM121 and NDC1 bind the Nup93 complex IEA Schizosaccharomyces pombe 23367 R-SPO-983140 https://reactome.org/PathwayBrowser/#/R-SPO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Schizosaccharomyces pombe 23367 R-SPO-983147 https://reactome.org/PathwayBrowser/#/R-SPO-983147 Release of E3 from polyubiquitinated substrate IEA Schizosaccharomyces pombe 23367 R-SPO-983150 https://reactome.org/PathwayBrowser/#/R-SPO-983150 Proteasomal cleavage of substrate IEA Schizosaccharomyces pombe 23367 R-SPO-983156 https://reactome.org/PathwayBrowser/#/R-SPO-983156 Polyubiquitination of substrate IEA Schizosaccharomyces pombe 23367 R-SPO-983157 https://reactome.org/PathwayBrowser/#/R-SPO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Schizosaccharomyces pombe 23367 R-SSC-1006143 https://reactome.org/PathwayBrowser/#/R-SSC-1006143 CD46 binds C3b IEA Sus scrofa 23367 R-SSC-1006169 https://reactome.org/PathwayBrowser/#/R-SSC-1006169 Factor H binds host cell surface markers IEA Sus scrofa 23367 R-SSC-1222685 https://reactome.org/PathwayBrowser/#/R-SSC-1222685 Cathelicidin LL-37 binds to bacterial cell wall IEA Sus scrofa 23367 R-SSC-1236956 https://reactome.org/PathwayBrowser/#/R-SSC-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Sus scrofa 23367 R-SSC-1236958 https://reactome.org/PathwayBrowser/#/R-SSC-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Sus scrofa 23367 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa 23367 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa 23367 R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa 23367 R-SSC-166721 https://reactome.org/PathwayBrowser/#/R-SSC-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa IEA Sus scrofa 23367 R-SSC-166726 https://reactome.org/PathwayBrowser/#/R-SSC-166726 Activation of MASPs IEA Sus scrofa 23367 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa 23367 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa 23367 R-SSC-166795 https://reactome.org/PathwayBrowser/#/R-SSC-166795 Formation of Classical C3 convertase (C4b:C2a complex) IEA Sus scrofa 23367 R-SSC-166817 https://reactome.org/PathwayBrowser/#/R-SSC-166817 Cleavage of C3 by C3 convertases IEA Sus scrofa 23367 R-SSC-168947 https://reactome.org/PathwayBrowser/#/R-SSC-168947 Ligand binds to TLR10 IEA Sus scrofa 23367 R-SSC-173636 https://reactome.org/PathwayBrowser/#/R-SSC-173636 Formation of classic pathway C5 convertase IEA Sus scrofa 23367 R-SSC-173680 https://reactome.org/PathwayBrowser/#/R-SSC-173680 Activation of C5 IEA Sus scrofa 23367 R-SSC-173754 https://reactome.org/PathwayBrowser/#/R-SSC-173754 Properdin stabilizes C3b:Bb bound to cell surfaces IEA Sus scrofa 23367 R-SSC-174456 https://reactome.org/PathwayBrowser/#/R-SSC-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Sus scrofa 23367 R-SSC-174551 https://reactome.org/PathwayBrowser/#/R-SSC-174551 Formation of alternative pathway C5 convertase IEA Sus scrofa 23367 R-SSC-176702 https://reactome.org/PathwayBrowser/#/R-SSC-176702 Disassociation of Processive Complex and Completed Telomere End IEA Sus scrofa 23367 R-SSC-183122 https://reactome.org/PathwayBrowser/#/R-SSC-183122 Factor D cleaves C3b-bound Factor B IEA Sus scrofa 23367 R-SSC-183126 https://reactome.org/PathwayBrowser/#/R-SSC-183126 Factor B binds to surface-associated C3b IEA Sus scrofa 23367 R-SSC-203156 https://reactome.org/PathwayBrowser/#/R-SSC-203156 Platelet-derived TREM-1 ligand binds to TREM-1 IEA Sus scrofa 23367 R-SSC-203973 https://reactome.org/PathwayBrowser/#/R-SSC-203973 Vesicle budding IEA Sus scrofa 23367 R-SSC-204008 https://reactome.org/PathwayBrowser/#/R-SSC-204008 SEC31:SEC13 and v-SNARE recruitment IEA Sus scrofa 23367 R-SSC-2130706 https://reactome.org/PathwayBrowser/#/R-SSC-2130706 MHC class II antigen processing IEA Sus scrofa 23367 R-SSC-2213240 https://reactome.org/PathwayBrowser/#/R-SSC-2213240 Reduction of disulphide bonds in MHC II antigens IEA Sus scrofa 23367 R-SSC-2408524 https://reactome.org/PathwayBrowser/#/R-SSC-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Sus scrofa 23367 R-SSC-2466068 https://reactome.org/PathwayBrowser/#/R-SSC-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Sus scrofa 23367 R-SSC-2467794 https://reactome.org/PathwayBrowser/#/R-SSC-2467794 Resolution of sister chromatids IEA Sus scrofa 23367 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa 23367 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa 23367 R-SSC-2468039 https://reactome.org/PathwayBrowser/#/R-SSC-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Sus scrofa 23367 R-SSC-2468041 https://reactome.org/PathwayBrowser/#/R-SSC-2468041 CDCA5 (Sororin) enables cohesion of sister chromosomal arms IEA Sus scrofa 23367 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa 23367 R-SSC-2468293 https://reactome.org/PathwayBrowser/#/R-SSC-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Sus scrofa 23367 R-SSC-2470935 https://reactome.org/PathwayBrowser/#/R-SSC-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Sus scrofa 23367 R-SSC-2473151 https://reactome.org/PathwayBrowser/#/R-SSC-2473151 CDCA5 (Sororin) enables cohesion of sister centromeres IEA Sus scrofa 23367 R-SSC-2473152 https://reactome.org/PathwayBrowser/#/R-SSC-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Sus scrofa 23367 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa 23367 R-SSC-2993898 https://reactome.org/PathwayBrowser/#/R-SSC-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Sus scrofa 23367 R-SSC-2995376 https://reactome.org/PathwayBrowser/#/R-SSC-2995376 BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins IEA Sus scrofa 23367 R-SSC-3785711 https://reactome.org/PathwayBrowser/#/R-SSC-3785711 Telomere shortening during replicative exhaustion IEA Sus scrofa 23367 R-SSC-5324632 https://reactome.org/PathwayBrowser/#/R-SSC-5324632 Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates IEA Sus scrofa 23367 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa 23367 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa 23367 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Sus scrofa 23367 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa 23367 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa 23367 R-SSC-5638014 https://reactome.org/PathwayBrowser/#/R-SSC-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Sus scrofa 23367 R-SSC-5693620 https://reactome.org/PathwayBrowser/#/R-SSC-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Sus scrofa 23367 R-SSC-5694417 https://reactome.org/PathwayBrowser/#/R-SSC-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Sus scrofa 23367 R-SSC-5694436 https://reactome.org/PathwayBrowser/#/R-SSC-5694436 MIA2 and MIA3 dissociate from procollagen VII vesicle IEA Sus scrofa 23367 R-SSC-5694522 https://reactome.org/PathwayBrowser/#/R-SSC-5694522 Inner coat assembly and cargo binding IEA Sus scrofa 23367 R-SSC-5694527 https://reactome.org/PathwayBrowser/#/R-SSC-5694527 Loss of SAR1B GTPase IEA Sus scrofa 23367 R-SSC-6789031 https://reactome.org/PathwayBrowser/#/R-SSC-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 23367 R-SSC-6789136 https://reactome.org/PathwayBrowser/#/R-SSC-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Sus scrofa 23367 R-SSC-6801762 https://reactome.org/PathwayBrowser/#/R-SSC-6801762 REG3A oligomerize to form a pore complex IEA Sus scrofa 23367 R-SSC-6801776 https://reactome.org/PathwayBrowser/#/R-SSC-6801776 REG3A binds bacterial phospholipids IEA Sus scrofa 23367 R-SSC-6806732 https://reactome.org/PathwayBrowser/#/R-SSC-6806732 GNLY binds the bacterial cell surface IEA Sus scrofa 23367 R-SSC-6807578 https://reactome.org/PathwayBrowser/#/R-SSC-6807578 GNLY binds the bacterial cell surface in the phagosome IEA Sus scrofa 23367 R-SSC-6808566 https://reactome.org/PathwayBrowser/#/R-SSC-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Sus scrofa 23367 R-SSC-6809521 https://reactome.org/PathwayBrowser/#/R-SSC-6809521 BPIF binds bacteria IEA Sus scrofa 23367 R-SSC-6810643 https://reactome.org/PathwayBrowser/#/R-SSC-6810643 EPPIN protein complex binds bacteria IEA Sus scrofa 23367 R-SSC-6813626 https://reactome.org/PathwayBrowser/#/R-SSC-6813626 LEAP2 binds bacteria IEA Sus scrofa 23367 R-SSC-6813659 https://reactome.org/PathwayBrowser/#/R-SSC-6813659 ELANE, CTSG or PRTN3 binds bacteria IEA Sus scrofa 23367 R-SSC-6814187 https://reactome.org/PathwayBrowser/#/R-SSC-6814187 EVL:PPL heterodimer binds the inner surface of the plasma membrane IEA Sus scrofa 23367 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa 23367 R-SSC-77592 https://reactome.org/PathwayBrowser/#/R-SSC-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Sus scrofa 23367 R-SSC-8851979 https://reactome.org/PathwayBrowser/#/R-SSC-8851979 BTNL9 binds immune cell surfaces IEA Sus scrofa 23367 R-SSC-8851988 https://reactome.org/PathwayBrowser/#/R-SSC-8851988 BTN2A2 binds T cell surface IEA Sus scrofa 23367 R-SSC-8852010 https://reactome.org/PathwayBrowser/#/R-SSC-8852010 BTNL2 binds activated T cells surface IEA Sus scrofa 23367 R-SSC-8852509 https://reactome.org/PathwayBrowser/#/R-SSC-8852509 CL-LK binds carbohydrates on target cell surface IEA Sus scrofa 23367 R-SSC-8862771 https://reactome.org/PathwayBrowser/#/R-SSC-8862771 PLA2G2A binds bacterial phospholipids IEA Sus scrofa 23367 R-SSC-8948027 https://reactome.org/PathwayBrowser/#/R-SSC-8948027 RNASEs bind bacterial phospholipids IEA Sus scrofa 23367 R-SSC-8951486 https://reactome.org/PathwayBrowser/#/R-SSC-8951486 CD46 binds C4b IEA Sus scrofa 23367 R-SSC-9615901 https://reactome.org/PathwayBrowser/#/R-SSC-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Sus scrofa 23367 R-SSC-9618378 https://reactome.org/PathwayBrowser/#/R-SSC-9618378 POM121 binds the Nup107-Nup160 complex IEA Sus scrofa 23367 R-SSC-9624876 https://reactome.org/PathwayBrowser/#/R-SSC-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Sus scrofa 23367 R-SSC-9624893 https://reactome.org/PathwayBrowser/#/R-SSC-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Sus scrofa 23367 R-SSC-9629195 https://reactome.org/PathwayBrowser/#/R-SSC-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Sus scrofa 23367 R-SSC-9629216 https://reactome.org/PathwayBrowser/#/R-SSC-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Sus scrofa 23367 R-SSC-9634169 https://reactome.org/PathwayBrowser/#/R-SSC-9634169 POM121 and NDC1 bind the Nup93 complex IEA Sus scrofa 23367 R-SSC-9670101 https://reactome.org/PathwayBrowser/#/R-SSC-9670101 ATRX:DAXX binds to subtelomeric chromosomal regions IEA Sus scrofa 23367 R-SSC-977359 https://reactome.org/PathwayBrowser/#/R-SSC-977359 Complement factor I binds to membrane-associated Factor H:C3b IEA Sus scrofa 23367 R-SSC-977363 https://reactome.org/PathwayBrowser/#/R-SSC-977363 Factor H binds to C3bBb IEA Sus scrofa 23367 R-SSC-977371 https://reactome.org/PathwayBrowser/#/R-SSC-977371 Factor I inactivates Factor H-boundC3b IEA Sus scrofa 23367 R-SSC-977375 https://reactome.org/PathwayBrowser/#/R-SSC-977375 CR1 binds C3bBb/C4bC2a IEA Sus scrofa 23367 R-SSC-977602 https://reactome.org/PathwayBrowser/#/R-SSC-977602 Complement factor I binds to MCP, CR1:C4b, C3b IEA Sus scrofa 23367 R-SSC-977605 https://reactome.org/PathwayBrowser/#/R-SSC-977605 Factor H displaces Bb IEA Sus scrofa 23367 R-SSC-977615 https://reactome.org/PathwayBrowser/#/R-SSC-977615 Factor I inactivates MCP/CR1-bound C4b/C3b IEA Sus scrofa 23367 R-SSC-977619 https://reactome.org/PathwayBrowser/#/R-SSC-977619 CD55 (DAF) promotes C3bBb/C4bC2a dissociation IEA Sus scrofa 23367 R-SSC-977629 https://reactome.org/PathwayBrowser/#/R-SSC-977629 Displacement of C2a/Bb by CR1 IEA Sus scrofa 23367 R-SSC-981535 https://reactome.org/PathwayBrowser/#/R-SSC-981535 CD55 (DAF) binds C3bBb, C4bC2a IEA Sus scrofa 23367 R-SSC-981539 https://reactome.org/PathwayBrowser/#/R-SSC-981539 C3b binds to cell surface IEA Sus scrofa 23367 R-SSC-981621 https://reactome.org/PathwayBrowser/#/R-SSC-981621 C3 convertases spontaneously dissociate IEA Sus scrofa 23367 R-SSC-981713 https://reactome.org/PathwayBrowser/#/R-SSC-981713 C4b binds to cell surface IEA Sus scrofa 23367 R-SSC-981728 https://reactome.org/PathwayBrowser/#/R-SSC-981728 Factor H binds to membrane-associated C3b IEA Sus scrofa 23367 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa 23367 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa 23367 R-SSC-983150 https://reactome.org/PathwayBrowser/#/R-SSC-983150 Proteasomal cleavage of substrate IEA Sus scrofa 23367 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa 23367 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa 23367 R-XTR-1006169 https://reactome.org/PathwayBrowser/#/R-XTR-1006169 Factor H binds host cell surface markers IEA Xenopus tropicalis 23367 R-XTR-1236956 https://reactome.org/PathwayBrowser/#/R-XTR-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Xenopus tropicalis 23367 R-XTR-1236958 https://reactome.org/PathwayBrowser/#/R-XTR-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Xenopus tropicalis 23367 R-XTR-1638803 https://reactome.org/PathwayBrowser/#/R-XTR-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Xenopus tropicalis 23367 R-XTR-1638821 https://reactome.org/PathwayBrowser/#/R-XTR-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Xenopus tropicalis 23367 R-XTR-166795 https://reactome.org/PathwayBrowser/#/R-XTR-166795 Formation of Classical C3 convertase (C4b:C2a complex) IEA Xenopus tropicalis 23367 R-XTR-166817 https://reactome.org/PathwayBrowser/#/R-XTR-166817 Cleavage of C3 by C3 convertases IEA Xenopus tropicalis 23367 R-XTR-168947 https://reactome.org/PathwayBrowser/#/R-XTR-168947 Ligand binds to TLR10 IEA Xenopus tropicalis 23367 R-XTR-173636 https://reactome.org/PathwayBrowser/#/R-XTR-173636 Formation of classic pathway C5 convertase IEA Xenopus tropicalis 23367 R-XTR-173754 https://reactome.org/PathwayBrowser/#/R-XTR-173754 Properdin stabilizes C3b:Bb bound to cell surfaces IEA Xenopus tropicalis 23367 R-XTR-174551 https://reactome.org/PathwayBrowser/#/R-XTR-174551 Formation of alternative pathway C5 convertase IEA Xenopus tropicalis 23367 R-XTR-176700 https://reactome.org/PathwayBrowser/#/R-XTR-176700 Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure IEA Xenopus tropicalis 23367 R-XTR-181450 https://reactome.org/PathwayBrowser/#/R-XTR-181450 Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure IEA Xenopus tropicalis 23367 R-XTR-183122 https://reactome.org/PathwayBrowser/#/R-XTR-183122 Factor D cleaves C3b-bound Factor B IEA Xenopus tropicalis 23367 R-XTR-183126 https://reactome.org/PathwayBrowser/#/R-XTR-183126 Factor B binds to surface-associated C3b IEA Xenopus tropicalis 23367 R-XTR-2130706 https://reactome.org/PathwayBrowser/#/R-XTR-2130706 MHC class II antigen processing IEA Xenopus tropicalis 23367 R-XTR-2213240 https://reactome.org/PathwayBrowser/#/R-XTR-2213240 Reduction of disulphide bonds in MHC II antigens IEA Xenopus tropicalis 23367 R-XTR-2408524 https://reactome.org/PathwayBrowser/#/R-XTR-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Xenopus tropicalis 23367 R-XTR-2466068 https://reactome.org/PathwayBrowser/#/R-XTR-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Xenopus tropicalis 23367 R-XTR-2467809 https://reactome.org/PathwayBrowser/#/R-XTR-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Xenopus tropicalis 23367 R-XTR-2468287 https://reactome.org/PathwayBrowser/#/R-XTR-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Xenopus tropicalis 23367 R-XTR-2468293 https://reactome.org/PathwayBrowser/#/R-XTR-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Xenopus tropicalis 23367 R-XTR-2484822 https://reactome.org/PathwayBrowser/#/R-XTR-2484822 Kinetochore assembly IEA Xenopus tropicalis 23367 R-XTR-3785711 https://reactome.org/PathwayBrowser/#/R-XTR-3785711 Telomere shortening during replicative exhaustion IEA Xenopus tropicalis 23367 R-XTR-5617816 https://reactome.org/PathwayBrowser/#/R-XTR-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Xenopus tropicalis 23367 R-XTR-5638009 https://reactome.org/PathwayBrowser/#/R-XTR-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Xenopus tropicalis 23367 R-XTR-5638014 https://reactome.org/PathwayBrowser/#/R-XTR-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Xenopus tropicalis 23367 R-XTR-5694522 https://reactome.org/PathwayBrowser/#/R-XTR-5694522 Inner coat assembly and cargo binding IEA Xenopus tropicalis 23367 R-XTR-5694527 https://reactome.org/PathwayBrowser/#/R-XTR-5694527 Loss of SAR1B GTPase IEA Xenopus tropicalis 23367 R-XTR-6801762 https://reactome.org/PathwayBrowser/#/R-XTR-6801762 REG3A oligomerize to form a pore complex IEA Xenopus tropicalis 23367 R-XTR-6801776 https://reactome.org/PathwayBrowser/#/R-XTR-6801776 REG3A binds bacterial phospholipids IEA Xenopus tropicalis 23367 R-XTR-6808566 https://reactome.org/PathwayBrowser/#/R-XTR-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Xenopus tropicalis 23367 R-XTR-6809521 https://reactome.org/PathwayBrowser/#/R-XTR-6809521 BPIF binds bacteria IEA Xenopus tropicalis 23367 R-XTR-6813659 https://reactome.org/PathwayBrowser/#/R-XTR-6813659 ELANE, CTSG or PRTN3 binds bacteria IEA Xenopus tropicalis 23367 R-XTR-6814187 https://reactome.org/PathwayBrowser/#/R-XTR-6814187 EVL:PPL heterodimer binds the inner surface of the plasma membrane IEA Xenopus tropicalis 23367 R-XTR-8851038 https://reactome.org/PathwayBrowser/#/R-XTR-8851038 BTN3A1 binds prenylated phosphoantigens IEA Xenopus tropicalis 23367 R-XTR-8851436 https://reactome.org/PathwayBrowser/#/R-XTR-8851436 CFHR dimers bind C3b IEA Xenopus tropicalis 23367 R-XTR-8851979 https://reactome.org/PathwayBrowser/#/R-XTR-8851979 BTNL9 binds immune cell surfaces IEA Xenopus tropicalis 23367 R-XTR-8851988 https://reactome.org/PathwayBrowser/#/R-XTR-8851988 BTN2A2 binds T cell surface IEA Xenopus tropicalis 23367 R-XTR-8852010 https://reactome.org/PathwayBrowser/#/R-XTR-8852010 BTNL2 binds activated T cells surface IEA Xenopus tropicalis 23367 R-XTR-8852013 https://reactome.org/PathwayBrowser/#/R-XTR-8852013 BTNL8 binds resting T cell surface IEA Xenopus tropicalis 23367 R-XTR-8862771 https://reactome.org/PathwayBrowser/#/R-XTR-8862771 PLA2G2A binds bacterial phospholipids IEA Xenopus tropicalis 23367 R-XTR-9615901 https://reactome.org/PathwayBrowser/#/R-XTR-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Xenopus tropicalis 23367 R-XTR-9624876 https://reactome.org/PathwayBrowser/#/R-XTR-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Xenopus tropicalis 23367 R-XTR-9624893 https://reactome.org/PathwayBrowser/#/R-XTR-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Xenopus tropicalis 23367 R-XTR-9629195 https://reactome.org/PathwayBrowser/#/R-XTR-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Xenopus tropicalis 23367 R-XTR-9629216 https://reactome.org/PathwayBrowser/#/R-XTR-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Xenopus tropicalis 23367 R-XTR-977359 https://reactome.org/PathwayBrowser/#/R-XTR-977359 Complement factor I binds to membrane-associated Factor H:C3b IEA Xenopus tropicalis 23367 R-XTR-977363 https://reactome.org/PathwayBrowser/#/R-XTR-977363 Factor H binds to C3bBb IEA Xenopus tropicalis 23367 R-XTR-977371 https://reactome.org/PathwayBrowser/#/R-XTR-977371 Factor I inactivates Factor H-boundC3b IEA Xenopus tropicalis 23367 R-XTR-977605 https://reactome.org/PathwayBrowser/#/R-XTR-977605 Factor H displaces Bb IEA Xenopus tropicalis 23367 R-XTR-977619 https://reactome.org/PathwayBrowser/#/R-XTR-977619 CD55 (DAF) promotes C3bBb/C4bC2a dissociation IEA Xenopus tropicalis 23367 R-XTR-981535 https://reactome.org/PathwayBrowser/#/R-XTR-981535 CD55 (DAF) binds C3bBb, C4bC2a IEA Xenopus tropicalis 23367 R-XTR-981539 https://reactome.org/PathwayBrowser/#/R-XTR-981539 C3b binds to cell surface IEA Xenopus tropicalis 23367 R-XTR-981621 https://reactome.org/PathwayBrowser/#/R-XTR-981621 C3 convertases spontaneously dissociate IEA Xenopus tropicalis 23367 R-XTR-981713 https://reactome.org/PathwayBrowser/#/R-XTR-981713 C4b binds to cell surface IEA Xenopus tropicalis 23367 R-XTR-981728 https://reactome.org/PathwayBrowser/#/R-XTR-981728 Factor H binds to membrane-associated C3b IEA Xenopus tropicalis 23367 R-XTR-983140 https://reactome.org/PathwayBrowser/#/R-XTR-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Xenopus tropicalis 23367 R-XTR-983147 https://reactome.org/PathwayBrowser/#/R-XTR-983147 Release of E3 from polyubiquitinated substrate IEA Xenopus tropicalis 23367 R-XTR-983156 https://reactome.org/PathwayBrowser/#/R-XTR-983156 Polyubiquitination of substrate IEA Xenopus tropicalis 23367 R-XTR-983157 https://reactome.org/PathwayBrowser/#/R-XTR-983157 Interaction of E3 with substrate and E2-Ub complex IEA Xenopus tropicalis 2366 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 2366 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2366 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2366 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2366 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 2366 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 2366 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2366 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2366 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2366 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 2366 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 2366 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2366 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 2366 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 2366 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2366 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 2366 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2366 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 2366 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 2366 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2366 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2366 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2366 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 2366 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 2366 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 2366 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 2366 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2366 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2366 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2366 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 2366 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 2366 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2366 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 2366 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 2366 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2366 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2366 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2366 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 2366 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 2366 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2366 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 2366 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 23736 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 23736 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 23736 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 23736 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 23736 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 23736 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 23736 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 23736 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 23736 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 23736 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 23781 R-BTA-5663050 https://reactome.org/PathwayBrowser/#/R-BTA-5663050 DHI and DHICA polymerize forming eumelanin IEA Bos taurus 23781 R-CEL-5663050 https://reactome.org/PathwayBrowser/#/R-CEL-5663050 DHI and DHICA polymerize forming eumelanin IEA Caenorhabditis elegans 23781 R-CFA-5663050 https://reactome.org/PathwayBrowser/#/R-CFA-5663050 DHI and DHICA polymerize forming eumelanin IEA Canis familiaris 23781 R-DDI-5663050 https://reactome.org/PathwayBrowser/#/R-DDI-5663050 DHI and DHICA polymerize forming eumelanin IEA Dictyostelium discoideum 23781 R-GGA-5663050 https://reactome.org/PathwayBrowser/#/R-GGA-5663050 DHI and DHICA polymerize forming eumelanin IEA Gallus gallus 23781 R-HSA-5663050 https://reactome.org/PathwayBrowser/#/R-HSA-5663050 DHI and DHICA polymerize forming eumelanin TAS Homo sapiens 23781 R-MMU-5663050 https://reactome.org/PathwayBrowser/#/R-MMU-5663050 DHI and DHICA polymerize forming eumelanin IEA Mus musculus 23781 R-RNO-5663050 https://reactome.org/PathwayBrowser/#/R-RNO-5663050 DHI and DHICA polymerize forming eumelanin IEA Rattus norvegicus 23781 R-SSC-5663050 https://reactome.org/PathwayBrowser/#/R-SSC-5663050 DHI and DHICA polymerize forming eumelanin IEA Sus scrofa 23781 R-XTR-5663050 https://reactome.org/PathwayBrowser/#/R-XTR-5663050 DHI and DHICA polymerize forming eumelanin IEA Xenopus tropicalis 2379 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 2379 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 2379 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 2379 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 2379 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 2379 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 2379 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 2379 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 2379 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 2379 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 2379 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 2379 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 2379 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 2379 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 2379 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 2379 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 2379 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 2379 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 2379 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 2379 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 2379 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 2379 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 2379 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 2379 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 2379 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 2379 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 2379 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 2379 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 2379 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 2379 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 2379 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 2379 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 2379 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 2379 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 2379 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 2379 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 2379 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 24103 R-CEL-6788867 https://reactome.org/PathwayBrowser/#/R-CEL-6788867 FN3K phosphorylates ketosamines IEA Caenorhabditis elegans 24103 R-CFA-6788867 https://reactome.org/PathwayBrowser/#/R-CFA-6788867 FN3K phosphorylates ketosamines IEA Canis familiaris 24103 R-DRE-6788867 https://reactome.org/PathwayBrowser/#/R-DRE-6788867 FN3K phosphorylates ketosamines IEA Danio rerio 24103 R-GGA-6788867 https://reactome.org/PathwayBrowser/#/R-GGA-6788867 FN3K phosphorylates ketosamines IEA Gallus gallus 24103 R-HSA-6788867 https://reactome.org/PathwayBrowser/#/R-HSA-6788867 FN3K phosphorylates ketosamines TAS Homo sapiens 24103 R-MMU-6788867 https://reactome.org/PathwayBrowser/#/R-MMU-6788867 FN3K phosphorylates ketosamines IEA Mus musculus 24103 R-RNO-6788867 https://reactome.org/PathwayBrowser/#/R-RNO-6788867 FN3K phosphorylates ketosamines IEA Rattus norvegicus 24103 R-SSC-6788867 https://reactome.org/PathwayBrowser/#/R-SSC-6788867 FN3K phosphorylates ketosamines IEA Sus scrofa 24103 R-XTR-6788867 https://reactome.org/PathwayBrowser/#/R-XTR-6788867 FN3K phosphorylates ketosamines IEA Xenopus tropicalis 24261 R-HSA-9662781 https://reactome.org/PathwayBrowser/#/R-HSA-9662781 CD163 gene produces CD163 protein TAS Homo sapiens 24402 R-BTA-5340320 https://reactome.org/PathwayBrowser/#/R-BTA-5340320 GLTP transports GSL from plasma membrane to ER membrane IEA Bos taurus 24402 R-CFA-5340320 https://reactome.org/PathwayBrowser/#/R-CFA-5340320 GLTP transports GSL from plasma membrane to ER membrane IEA Canis familiaris 24402 R-DRE-5340320 https://reactome.org/PathwayBrowser/#/R-DRE-5340320 GLTP transports GSL from plasma membrane to ER membrane IEA Danio rerio 24402 R-GGA-5340320 https://reactome.org/PathwayBrowser/#/R-GGA-5340320 GLTP transports GSL from plasma membrane to ER membrane IEA Gallus gallus 24402 R-HSA-5340320 https://reactome.org/PathwayBrowser/#/R-HSA-5340320 GLTP transports GSL from plasma membrane to ER membrane TAS Homo sapiens 24402 R-MMU-5340320 https://reactome.org/PathwayBrowser/#/R-MMU-5340320 GLTP transports GSL from plasma membrane to ER membrane IEA Mus musculus 24402 R-PFA-5340320 https://reactome.org/PathwayBrowser/#/R-PFA-5340320 GLTP transports GSL from plasma membrane to ER membrane IEA Plasmodium falciparum 24402 R-RNO-5340320 https://reactome.org/PathwayBrowser/#/R-RNO-5340320 GLTP transports GSL from plasma membrane to ER membrane IEA Rattus norvegicus 24402 R-SSC-5340320 https://reactome.org/PathwayBrowser/#/R-SSC-5340320 GLTP transports GSL from plasma membrane to ER membrane IEA Sus scrofa 24402 R-XTR-5340320 https://reactome.org/PathwayBrowser/#/R-XTR-5340320 GLTP transports GSL from plasma membrane to ER membrane IEA Xenopus tropicalis 24431 R-HSA-5662891 https://reactome.org/PathwayBrowser/#/R-HSA-5662891 pheomelanin formation TAS Homo sapiens 24499 R-BTA-174757 https://reactome.org/PathwayBrowser/#/R-BTA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Bos taurus 24499 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 24499 R-BTA-6784628 https://reactome.org/PathwayBrowser/#/R-BTA-6784628 PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Bos taurus 24499 R-BTA-6784676 https://reactome.org/PathwayBrowser/#/R-BTA-6784676 PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Bos taurus 24499 R-BTA-6784861 https://reactome.org/PathwayBrowser/#/R-BTA-6784861 HSPG binds LPL dimer IEA Bos taurus 24499 R-BTA-8857928 https://reactome.org/PathwayBrowser/#/R-BTA-8857928 GPIHBP1 binds HSPG:LPL dimer IEA Bos taurus 24499 R-CFA-174757 https://reactome.org/PathwayBrowser/#/R-CFA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Canis familiaris 24499 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 24499 R-CFA-6784628 https://reactome.org/PathwayBrowser/#/R-CFA-6784628 PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Canis familiaris 24499 R-CFA-6784676 https://reactome.org/PathwayBrowser/#/R-CFA-6784676 PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Canis familiaris 24499 R-CFA-6784861 https://reactome.org/PathwayBrowser/#/R-CFA-6784861 HSPG binds LPL dimer IEA Canis familiaris 24499 R-CFA-8857928 https://reactome.org/PathwayBrowser/#/R-CFA-8857928 GPIHBP1 binds HSPG:LPL dimer IEA Canis familiaris 24499 R-DME-6784628 https://reactome.org/PathwayBrowser/#/R-DME-6784628 PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Drosophila melanogaster 24499 R-DME-6784676 https://reactome.org/PathwayBrowser/#/R-DME-6784676 PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Drosophila melanogaster 24499 R-DME-6784861 https://reactome.org/PathwayBrowser/#/R-DME-6784861 HSPG binds LPL dimer IEA Drosophila melanogaster 24499 R-DME-8857928 https://reactome.org/PathwayBrowser/#/R-DME-8857928 GPIHBP1 binds HSPG:LPL dimer IEA Drosophila melanogaster 24499 R-DRE-6784861 https://reactome.org/PathwayBrowser/#/R-DRE-6784861 HSPG binds LPL dimer IEA Danio rerio 24499 R-GGA-6784628 https://reactome.org/PathwayBrowser/#/R-GGA-6784628 PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Gallus gallus 24499 R-GGA-6784676 https://reactome.org/PathwayBrowser/#/R-GGA-6784676 PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Gallus gallus 24499 R-GGA-6784861 https://reactome.org/PathwayBrowser/#/R-GGA-6784861 HSPG binds LPL dimer IEA Gallus gallus 24499 R-GGA-8857928 https://reactome.org/PathwayBrowser/#/R-GGA-8857928 GPIHBP1 binds HSPG:LPL dimer IEA Gallus gallus 24499 R-HSA-174757 https://reactome.org/PathwayBrowser/#/R-HSA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols TAS Homo sapiens 24499 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 24499 R-HSA-6784628 https://reactome.org/PathwayBrowser/#/R-HSA-6784628 PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer TAS Homo sapiens 24499 R-HSA-6784676 https://reactome.org/PathwayBrowser/#/R-HSA-6784676 PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer TAS Homo sapiens 24499 R-HSA-6784861 https://reactome.org/PathwayBrowser/#/R-HSA-6784861 HSPG binds LPL dimer TAS Homo sapiens 24499 R-HSA-8857928 https://reactome.org/PathwayBrowser/#/R-HSA-8857928 GPIHBP1 binds HSPG:LPL dimer TAS Homo sapiens 24499 R-HSA-9609689 https://reactome.org/PathwayBrowser/#/R-HSA-9609689 HCMV Binds to the Host Cell via heparan sulfate proteoglycans (HSPG) TAS Homo sapiens 24499 R-HSA-9610867 https://reactome.org/PathwayBrowser/#/R-HSA-9610867 HCMV Binds Host Cell Receptor - Endocytic Pathway TAS Homo sapiens 24499 R-HSA-9611147 https://reactome.org/PathwayBrowser/#/R-HSA-9611147 Endocytic Uptake of HCMV Virion TAS Homo sapiens 24499 R-HSA-9611158 https://reactome.org/PathwayBrowser/#/R-HSA-9611158 Fusion of HCMV Envelope with Plasma Membrane TAS Homo sapiens 24499 R-MMU-174757 https://reactome.org/PathwayBrowser/#/R-MMU-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Mus musculus 24499 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 24499 R-MMU-6784628 https://reactome.org/PathwayBrowser/#/R-MMU-6784628 PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Mus musculus 24499 R-MMU-6784676 https://reactome.org/PathwayBrowser/#/R-MMU-6784676 PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Mus musculus 24499 R-MMU-6784861 https://reactome.org/PathwayBrowser/#/R-MMU-6784861 HSPG binds LPL dimer IEA Mus musculus 24499 R-MMU-8857928 https://reactome.org/PathwayBrowser/#/R-MMU-8857928 GPIHBP1 binds HSPG:LPL dimer IEA Mus musculus 24499 R-RNO-174757 https://reactome.org/PathwayBrowser/#/R-RNO-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Rattus norvegicus 24499 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 24499 R-RNO-6784628 https://reactome.org/PathwayBrowser/#/R-RNO-6784628 PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Rattus norvegicus 24499 R-RNO-6784676 https://reactome.org/PathwayBrowser/#/R-RNO-6784676 PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Rattus norvegicus 24499 R-RNO-6784861 https://reactome.org/PathwayBrowser/#/R-RNO-6784861 HSPG binds LPL dimer IEA Rattus norvegicus 24499 R-RNO-8857928 https://reactome.org/PathwayBrowser/#/R-RNO-8857928 GPIHBP1 binds HSPG:LPL dimer IEA Rattus norvegicus 24499 R-SSC-174757 https://reactome.org/PathwayBrowser/#/R-SSC-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Sus scrofa 24499 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 24499 R-SSC-6784628 https://reactome.org/PathwayBrowser/#/R-SSC-6784628 PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Sus scrofa 24499 R-SSC-6784676 https://reactome.org/PathwayBrowser/#/R-SSC-6784676 PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Sus scrofa 24499 R-SSC-6784861 https://reactome.org/PathwayBrowser/#/R-SSC-6784861 HSPG binds LPL dimer IEA Sus scrofa 24499 R-SSC-8857928 https://reactome.org/PathwayBrowser/#/R-SSC-8857928 GPIHBP1 binds HSPG:LPL dimer IEA Sus scrofa 24499 R-XTR-6784861 https://reactome.org/PathwayBrowser/#/R-XTR-6784861 HSPG binds LPL dimer IEA Xenopus tropicalis 24505 R-BTA-1006169 https://reactome.org/PathwayBrowser/#/R-BTA-1006169 Factor H binds host cell surface markers IEA Bos taurus 24505 R-BTA-1604763 https://reactome.org/PathwayBrowser/#/R-BTA-1604763 Autocatalytic activation of MMP7 IEA Bos taurus 24505 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 24505 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 24505 R-BTA-5694109 https://reactome.org/PathwayBrowser/#/R-BTA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Bos taurus 24505 R-BTA-6785213 https://reactome.org/PathwayBrowser/#/R-BTA-6785213 LIPC dimer binds heparin IEA Bos taurus 24505 R-BTA-977363 https://reactome.org/PathwayBrowser/#/R-BTA-977363 Factor H binds to C3bBb IEA Bos taurus 24505 R-BTA-981728 https://reactome.org/PathwayBrowser/#/R-BTA-981728 Factor H binds to membrane-associated C3b IEA Bos taurus 24505 R-CEL-1604763 https://reactome.org/PathwayBrowser/#/R-CEL-1604763 Autocatalytic activation of MMP7 IEA Caenorhabditis elegans 24505 R-CFA-1006169 https://reactome.org/PathwayBrowser/#/R-CFA-1006169 Factor H binds host cell surface markers IEA Canis familiaris 24505 R-CFA-1604763 https://reactome.org/PathwayBrowser/#/R-CFA-1604763 Autocatalytic activation of MMP7 IEA Canis familiaris 24505 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 24505 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 24505 R-CFA-5694109 https://reactome.org/PathwayBrowser/#/R-CFA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Canis familiaris 24505 R-CFA-6785213 https://reactome.org/PathwayBrowser/#/R-CFA-6785213 LIPC dimer binds heparin IEA Canis familiaris 24505 R-CFA-977363 https://reactome.org/PathwayBrowser/#/R-CFA-977363 Factor H binds to C3bBb IEA Canis familiaris 24505 R-CFA-981728 https://reactome.org/PathwayBrowser/#/R-CFA-981728 Factor H binds to membrane-associated C3b IEA Canis familiaris 24505 R-DME-1604763 https://reactome.org/PathwayBrowser/#/R-DME-1604763 Autocatalytic activation of MMP7 IEA Drosophila melanogaster 24505 R-DME-5694109 https://reactome.org/PathwayBrowser/#/R-DME-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Drosophila melanogaster 24505 R-DME-6785213 https://reactome.org/PathwayBrowser/#/R-DME-6785213 LIPC dimer binds heparin IEA Drosophila melanogaster 24505 R-DRE-1006169 https://reactome.org/PathwayBrowser/#/R-DRE-1006169 Factor H binds host cell surface markers IEA Danio rerio 24505 R-DRE-1604763 https://reactome.org/PathwayBrowser/#/R-DRE-1604763 Autocatalytic activation of MMP7 IEA Danio rerio 24505 R-DRE-5694109 https://reactome.org/PathwayBrowser/#/R-DRE-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Danio rerio 24505 R-DRE-6785213 https://reactome.org/PathwayBrowser/#/R-DRE-6785213 LIPC dimer binds heparin IEA Danio rerio 24505 R-DRE-977363 https://reactome.org/PathwayBrowser/#/R-DRE-977363 Factor H binds to C3bBb IEA Danio rerio 24505 R-DRE-981728 https://reactome.org/PathwayBrowser/#/R-DRE-981728 Factor H binds to membrane-associated C3b IEA Danio rerio 24505 R-GGA-1006169 https://reactome.org/PathwayBrowser/#/R-GGA-1006169 Factor H binds host cell surface markers IEA Gallus gallus 24505 R-GGA-1604763 https://reactome.org/PathwayBrowser/#/R-GGA-1604763 Autocatalytic activation of MMP7 IEA Gallus gallus 24505 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 24505 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 24505 R-GGA-5694109 https://reactome.org/PathwayBrowser/#/R-GGA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Gallus gallus 24505 R-GGA-6785213 https://reactome.org/PathwayBrowser/#/R-GGA-6785213 LIPC dimer binds heparin IEA Gallus gallus 24505 R-GGA-977363 https://reactome.org/PathwayBrowser/#/R-GGA-977363 Factor H binds to C3bBb IEA Gallus gallus 24505 R-GGA-981728 https://reactome.org/PathwayBrowser/#/R-GGA-981728 Factor H binds to membrane-associated C3b IEA Gallus gallus 24505 R-HSA-1006169 https://reactome.org/PathwayBrowser/#/R-HSA-1006169 Factor H binds host cell surface markers TAS Homo sapiens 24505 R-HSA-1604763 https://reactome.org/PathwayBrowser/#/R-HSA-1604763 Autocatalytic activation of MMP7 TAS Homo sapiens 24505 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 24505 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 24505 R-HSA-5694109 https://reactome.org/PathwayBrowser/#/R-HSA-5694109 LIPC dimer hydrolyses TAG to DAG and FA TAS Homo sapiens 24505 R-HSA-6785213 https://reactome.org/PathwayBrowser/#/R-HSA-6785213 LIPC dimer binds heparin TAS Homo sapiens 24505 R-HSA-977363 https://reactome.org/PathwayBrowser/#/R-HSA-977363 Factor H binds to C3bBb TAS Homo sapiens 24505 R-HSA-981728 https://reactome.org/PathwayBrowser/#/R-HSA-981728 Factor H binds to membrane-associated C3b TAS Homo sapiens 24505 R-MMU-1604763 https://reactome.org/PathwayBrowser/#/R-MMU-1604763 Autocatalytic activation of MMP7 IEA Mus musculus 24505 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 24505 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 24505 R-MMU-5694109 https://reactome.org/PathwayBrowser/#/R-MMU-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Mus musculus 24505 R-MMU-6785213 https://reactome.org/PathwayBrowser/#/R-MMU-6785213 LIPC dimer binds heparin IEA Mus musculus 24505 R-RNO-1604763 https://reactome.org/PathwayBrowser/#/R-RNO-1604763 Autocatalytic activation of MMP7 IEA Rattus norvegicus 24505 R-RNO-5694109 https://reactome.org/PathwayBrowser/#/R-RNO-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Rattus norvegicus 24505 R-RNO-6785213 https://reactome.org/PathwayBrowser/#/R-RNO-6785213 LIPC dimer binds heparin IEA Rattus norvegicus 24505 R-SSC-1006169 https://reactome.org/PathwayBrowser/#/R-SSC-1006169 Factor H binds host cell surface markers IEA Sus scrofa 24505 R-SSC-1604763 https://reactome.org/PathwayBrowser/#/R-SSC-1604763 Autocatalytic activation of MMP7 IEA Sus scrofa 24505 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 24505 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 24505 R-SSC-5694109 https://reactome.org/PathwayBrowser/#/R-SSC-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Sus scrofa 24505 R-SSC-6785213 https://reactome.org/PathwayBrowser/#/R-SSC-6785213 LIPC dimer binds heparin IEA Sus scrofa 24505 R-SSC-977363 https://reactome.org/PathwayBrowser/#/R-SSC-977363 Factor H binds to C3bBb IEA Sus scrofa 24505 R-SSC-981728 https://reactome.org/PathwayBrowser/#/R-SSC-981728 Factor H binds to membrane-associated C3b IEA Sus scrofa 24505 R-XTR-1006169 https://reactome.org/PathwayBrowser/#/R-XTR-1006169 Factor H binds host cell surface markers IEA Xenopus tropicalis 24505 R-XTR-1604763 https://reactome.org/PathwayBrowser/#/R-XTR-1604763 Autocatalytic activation of MMP7 IEA Xenopus tropicalis 24505 R-XTR-5694109 https://reactome.org/PathwayBrowser/#/R-XTR-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Xenopus tropicalis 24505 R-XTR-6785213 https://reactome.org/PathwayBrowser/#/R-XTR-6785213 LIPC dimer binds heparin IEA Xenopus tropicalis 24505 R-XTR-977363 https://reactome.org/PathwayBrowser/#/R-XTR-977363 Factor H binds to C3bBb IEA Xenopus tropicalis 24505 R-XTR-981728 https://reactome.org/PathwayBrowser/#/R-XTR-981728 Factor H binds to membrane-associated C3b IEA Xenopus tropicalis 2453 R-BTA-561041 https://reactome.org/PathwayBrowser/#/R-BTA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Bos taurus 2453 R-BTA-6784959 https://reactome.org/PathwayBrowser/#/R-BTA-6784959 BPHL hydrolyses VACV to ACV IEA Bos taurus 2453 R-CEL-561041 https://reactome.org/PathwayBrowser/#/R-CEL-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Caenorhabditis elegans 2453 R-CEL-6784959 https://reactome.org/PathwayBrowser/#/R-CEL-6784959 BPHL hydrolyses VACV to ACV IEA Caenorhabditis elegans 2453 R-CFA-561041 https://reactome.org/PathwayBrowser/#/R-CFA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Canis familiaris 2453 R-CFA-6784959 https://reactome.org/PathwayBrowser/#/R-CFA-6784959 BPHL hydrolyses VACV to ACV IEA Canis familiaris 2453 R-DME-561041 https://reactome.org/PathwayBrowser/#/R-DME-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Drosophila melanogaster 2453 R-DME-6784959 https://reactome.org/PathwayBrowser/#/R-DME-6784959 BPHL hydrolyses VACV to ACV IEA Drosophila melanogaster 2453 R-DRE-561041 https://reactome.org/PathwayBrowser/#/R-DRE-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Danio rerio 2453 R-GGA-561041 https://reactome.org/PathwayBrowser/#/R-GGA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Gallus gallus 2453 R-GGA-6784959 https://reactome.org/PathwayBrowser/#/R-GGA-6784959 BPHL hydrolyses VACV to ACV IEA Gallus gallus 2453 R-HSA-561041 https://reactome.org/PathwayBrowser/#/R-HSA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids TAS Homo sapiens 2453 R-HSA-6784959 https://reactome.org/PathwayBrowser/#/R-HSA-6784959 BPHL hydrolyses VACV to ACV TAS Homo sapiens 2453 R-MMU-561041 https://reactome.org/PathwayBrowser/#/R-MMU-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Mus musculus 2453 R-MMU-6784959 https://reactome.org/PathwayBrowser/#/R-MMU-6784959 BPHL hydrolyses VACV to ACV IEA Mus musculus 2453 R-RNO-561041 https://reactome.org/PathwayBrowser/#/R-RNO-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Rattus norvegicus 2453 R-RNO-6784959 https://reactome.org/PathwayBrowser/#/R-RNO-6784959 BPHL hydrolyses VACV to ACV IEA Rattus norvegicus 2453 R-SSC-561041 https://reactome.org/PathwayBrowser/#/R-SSC-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Sus scrofa 2453 R-SSC-6784959 https://reactome.org/PathwayBrowser/#/R-SSC-6784959 BPHL hydrolyses VACV to ACV IEA Sus scrofa 2453 R-XTR-561041 https://reactome.org/PathwayBrowser/#/R-XTR-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Xenopus tropicalis 24636 R-HSA-3785704 https://reactome.org/PathwayBrowser/#/R-HSA-3785704 DSB inducing agents induce double strand DNA breaks TAS Homo sapiens 246422 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 246422 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 246422 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 246422 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 246422 R-BTA-109759 https://reactome.org/PathwayBrowser/#/R-BTA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Bos taurus 246422 R-BTA-73596 https://reactome.org/PathwayBrowser/#/R-BTA-73596 dCMP + H2O => dUMP + NH4+ IEA Bos taurus 246422 R-BTA-73605 https://reactome.org/PathwayBrowser/#/R-BTA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Bos taurus 246422 R-BTA-73635 https://reactome.org/PathwayBrowser/#/R-BTA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Bos taurus 246422 R-BTA-73666 https://reactome.org/PathwayBrowser/#/R-BTA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Bos taurus 246422 R-BTA-75126 https://reactome.org/PathwayBrowser/#/R-BTA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Bos taurus 246422 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 246422 R-CEL-73605 https://reactome.org/PathwayBrowser/#/R-CEL-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Caenorhabditis elegans 246422 R-CEL-73635 https://reactome.org/PathwayBrowser/#/R-CEL-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Caenorhabditis elegans 246422 R-CEL-73666 https://reactome.org/PathwayBrowser/#/R-CEL-73666 dUTP + H2O => dUMP + pyrophosphate IEA Caenorhabditis elegans 246422 R-CEL-75126 https://reactome.org/PathwayBrowser/#/R-CEL-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Caenorhabditis elegans 246422 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 246422 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 246422 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 246422 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 246422 R-CFA-109759 https://reactome.org/PathwayBrowser/#/R-CFA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Canis familiaris 246422 R-CFA-73596 https://reactome.org/PathwayBrowser/#/R-CFA-73596 dCMP + H2O => dUMP + NH4+ IEA Canis familiaris 246422 R-CFA-73605 https://reactome.org/PathwayBrowser/#/R-CFA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Canis familiaris 246422 R-CFA-73635 https://reactome.org/PathwayBrowser/#/R-CFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Canis familiaris 246422 R-CFA-73666 https://reactome.org/PathwayBrowser/#/R-CFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Canis familiaris 246422 R-CFA-75126 https://reactome.org/PathwayBrowser/#/R-CFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Canis familiaris 246422 R-DDI-73635 https://reactome.org/PathwayBrowser/#/R-DDI-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Dictyostelium discoideum 246422 R-DDI-73666 https://reactome.org/PathwayBrowser/#/R-DDI-73666 dUTP + H2O => dUMP + pyrophosphate IEA Dictyostelium discoideum 246422 R-DDI-75126 https://reactome.org/PathwayBrowser/#/R-DDI-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Dictyostelium discoideum 246422 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 246422 R-DME-109759 https://reactome.org/PathwayBrowser/#/R-DME-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Drosophila melanogaster 246422 R-DME-73605 https://reactome.org/PathwayBrowser/#/R-DME-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Drosophila melanogaster 246422 R-DME-73635 https://reactome.org/PathwayBrowser/#/R-DME-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Drosophila melanogaster 246422 R-DME-73666 https://reactome.org/PathwayBrowser/#/R-DME-73666 dUTP + H2O => dUMP + pyrophosphate IEA Drosophila melanogaster 246422 R-DME-75126 https://reactome.org/PathwayBrowser/#/R-DME-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Drosophila melanogaster 246422 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 246422 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 246422 R-DRE-73596 https://reactome.org/PathwayBrowser/#/R-DRE-73596 dCMP + H2O => dUMP + NH4+ IEA Danio rerio 246422 R-DRE-73605 https://reactome.org/PathwayBrowser/#/R-DRE-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Danio rerio 246422 R-DRE-73635 https://reactome.org/PathwayBrowser/#/R-DRE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Danio rerio 246422 R-DRE-73666 https://reactome.org/PathwayBrowser/#/R-DRE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Danio rerio 246422 R-DRE-75126 https://reactome.org/PathwayBrowser/#/R-DRE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Danio rerio 246422 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 246422 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 246422 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 246422 R-GGA-109759 https://reactome.org/PathwayBrowser/#/R-GGA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Gallus gallus 246422 R-GGA-73596 https://reactome.org/PathwayBrowser/#/R-GGA-73596 dCMP + H2O => dUMP + NH4+ IEA Gallus gallus 246422 R-GGA-73635 https://reactome.org/PathwayBrowser/#/R-GGA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Gallus gallus 246422 R-GGA-73666 https://reactome.org/PathwayBrowser/#/R-GGA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Gallus gallus 246422 R-GGA-75126 https://reactome.org/PathwayBrowser/#/R-GGA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Gallus gallus 246422 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 246422 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 246422 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 246422 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 246422 R-HSA-109759 https://reactome.org/PathwayBrowser/#/R-HSA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] TAS Homo sapiens 246422 R-HSA-73596 https://reactome.org/PathwayBrowser/#/R-HSA-73596 dCMP + H2O => dUMP + NH4+ TAS Homo sapiens 246422 R-HSA-73605 https://reactome.org/PathwayBrowser/#/R-HSA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate TAS Homo sapiens 246422 R-HSA-73635 https://reactome.org/PathwayBrowser/#/R-HSA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] TAS Homo sapiens 246422 R-HSA-73666 https://reactome.org/PathwayBrowser/#/R-HSA-73666 dUTP + H2O => dUMP + pyrophosphate TAS Homo sapiens 246422 R-HSA-75126 https://reactome.org/PathwayBrowser/#/R-HSA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] TAS Homo sapiens 246422 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 246422 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 246422 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 246422 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 246422 R-MMU-109759 https://reactome.org/PathwayBrowser/#/R-MMU-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Mus musculus 246422 R-MMU-73596 https://reactome.org/PathwayBrowser/#/R-MMU-73596 dCMP + H2O => dUMP + NH4+ IEA Mus musculus 246422 R-MMU-73605 https://reactome.org/PathwayBrowser/#/R-MMU-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Mus musculus 246422 R-MMU-73635 https://reactome.org/PathwayBrowser/#/R-MMU-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Mus musculus 246422 R-MMU-73666 https://reactome.org/PathwayBrowser/#/R-MMU-73666 dUTP + H2O => dUMP + pyrophosphate IEA Mus musculus 246422 R-MMU-75126 https://reactome.org/PathwayBrowser/#/R-MMU-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Mus musculus 246422 R-PFA-73605 https://reactome.org/PathwayBrowser/#/R-PFA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Plasmodium falciparum 246422 R-PFA-73635 https://reactome.org/PathwayBrowser/#/R-PFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Plasmodium falciparum 246422 R-PFA-73666 https://reactome.org/PathwayBrowser/#/R-PFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Plasmodium falciparum 246422 R-PFA-75126 https://reactome.org/PathwayBrowser/#/R-PFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Plasmodium falciparum 246422 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 246422 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 246422 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 246422 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 246422 R-RNO-109759 https://reactome.org/PathwayBrowser/#/R-RNO-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Rattus norvegicus 246422 R-RNO-73596 https://reactome.org/PathwayBrowser/#/R-RNO-73596 dCMP + H2O => dUMP + NH4+ IEA Rattus norvegicus 246422 R-RNO-73605 https://reactome.org/PathwayBrowser/#/R-RNO-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Rattus norvegicus 246422 R-RNO-73635 https://reactome.org/PathwayBrowser/#/R-RNO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Rattus norvegicus 246422 R-RNO-73666 https://reactome.org/PathwayBrowser/#/R-RNO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Rattus norvegicus 246422 R-RNO-75126 https://reactome.org/PathwayBrowser/#/R-RNO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Rattus norvegicus 246422 R-SCE-73605 https://reactome.org/PathwayBrowser/#/R-SCE-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Saccharomyces cerevisiae 246422 R-SCE-73635 https://reactome.org/PathwayBrowser/#/R-SCE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Saccharomyces cerevisiae 246422 R-SCE-73666 https://reactome.org/PathwayBrowser/#/R-SCE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Saccharomyces cerevisiae 246422 R-SCE-75126 https://reactome.org/PathwayBrowser/#/R-SCE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Saccharomyces cerevisiae 246422 R-SPO-73605 https://reactome.org/PathwayBrowser/#/R-SPO-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Schizosaccharomyces pombe 246422 R-SPO-73635 https://reactome.org/PathwayBrowser/#/R-SPO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Schizosaccharomyces pombe 246422 R-SPO-73666 https://reactome.org/PathwayBrowser/#/R-SPO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Schizosaccharomyces pombe 246422 R-SPO-75126 https://reactome.org/PathwayBrowser/#/R-SPO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Schizosaccharomyces pombe 246422 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 246422 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 246422 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 246422 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 246422 R-SSC-109759 https://reactome.org/PathwayBrowser/#/R-SSC-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Sus scrofa 246422 R-SSC-73596 https://reactome.org/PathwayBrowser/#/R-SSC-73596 dCMP + H2O => dUMP + NH4+ IEA Sus scrofa 246422 R-SSC-73605 https://reactome.org/PathwayBrowser/#/R-SSC-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Sus scrofa 246422 R-SSC-73635 https://reactome.org/PathwayBrowser/#/R-SSC-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Sus scrofa 246422 R-SSC-73666 https://reactome.org/PathwayBrowser/#/R-SSC-73666 dUTP + H2O => dUMP + pyrophosphate IEA Sus scrofa 246422 R-SSC-75126 https://reactome.org/PathwayBrowser/#/R-SSC-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Sus scrofa 246422 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 246422 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 246422 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 246422 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 246422 R-XTR-109759 https://reactome.org/PathwayBrowser/#/R-XTR-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Xenopus tropicalis 246422 R-XTR-73596 https://reactome.org/PathwayBrowser/#/R-XTR-73596 dCMP + H2O => dUMP + NH4+ IEA Xenopus tropicalis 246422 R-XTR-73605 https://reactome.org/PathwayBrowser/#/R-XTR-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Xenopus tropicalis 246422 R-XTR-73635 https://reactome.org/PathwayBrowser/#/R-XTR-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Xenopus tropicalis 246422 R-XTR-73666 https://reactome.org/PathwayBrowser/#/R-XTR-73666 dUTP + H2O => dUMP + pyrophosphate IEA Xenopus tropicalis 246422 R-XTR-75126 https://reactome.org/PathwayBrowser/#/R-XTR-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Xenopus tropicalis 24654 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 24654 R-BTA-2197646 https://reactome.org/PathwayBrowser/#/R-BTA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Bos taurus 24654 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 24654 R-BTA-2512800 https://reactome.org/PathwayBrowser/#/R-BTA-2512800 SCARB1:ligand is endocytosed IEA Bos taurus 24654 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 24654 R-BTA-8869667 https://reactome.org/PathwayBrowser/#/R-BTA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Bos taurus 24654 R-CFA-2197646 https://reactome.org/PathwayBrowser/#/R-CFA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Canis familiaris 24654 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 24654 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 24654 R-CFA-2512800 https://reactome.org/PathwayBrowser/#/R-CFA-2512800 SCARB1:ligand is endocytosed IEA Canis familiaris 24654 R-GGA-2197646 https://reactome.org/PathwayBrowser/#/R-GGA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Gallus gallus 24654 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 24654 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 24654 R-GGA-2512800 https://reactome.org/PathwayBrowser/#/R-GGA-2512800 SCARB1:ligand is endocytosed IEA Gallus gallus 24654 R-GGA-8869667 https://reactome.org/PathwayBrowser/#/R-GGA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Gallus gallus 24654 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 24654 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 24654 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 24654 R-HSA-2197645 https://reactome.org/PathwayBrowser/#/R-HSA-2197645 SCARF1 (SREC-I) binds ligands IEA Homo sapiens 24654 R-HSA-2197646 https://reactome.org/PathwayBrowser/#/R-HSA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands TAS Homo sapiens 24654 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 24654 R-HSA-2247514 https://reactome.org/PathwayBrowser/#/R-HSA-2247514 SCARF1:ligand is endocytosed TAS Homo sapiens 24654 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 24654 R-HSA-2512800 https://reactome.org/PathwayBrowser/#/R-HSA-2512800 SCARB1:ligand is endocytosed TAS Homo sapiens 24654 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 24654 R-HSA-8869667 https://reactome.org/PathwayBrowser/#/R-HSA-8869667 oxLDL:CD36 binds TLR4:TLR6 TAS Homo sapiens 24654 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 24654 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 24654 R-MMU-2197646 https://reactome.org/PathwayBrowser/#/R-MMU-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Mus musculus 24654 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 24654 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 24654 R-MMU-2512800 https://reactome.org/PathwayBrowser/#/R-MMU-2512800 SCARB1:ligand is endocytosed IEA Mus musculus 24654 R-MMU-8869667 https://reactome.org/PathwayBrowser/#/R-MMU-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Mus musculus 24654 R-RNO-2197646 https://reactome.org/PathwayBrowser/#/R-RNO-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Rattus norvegicus 24654 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 24654 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 24654 R-RNO-2512800 https://reactome.org/PathwayBrowser/#/R-RNO-2512800 SCARB1:ligand is endocytosed IEA Rattus norvegicus 24654 R-RNO-8869667 https://reactome.org/PathwayBrowser/#/R-RNO-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Rattus norvegicus 24654 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa 24654 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 24654 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 24654 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa 24654 R-SSC-8869667 https://reactome.org/PathwayBrowser/#/R-SSC-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Sus scrofa 24757 R-BTA-6789031 https://reactome.org/PathwayBrowser/#/R-BTA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 24757 R-BTA-6789126 https://reactome.org/PathwayBrowser/#/R-BTA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 24757 R-CEL-6789031 https://reactome.org/PathwayBrowser/#/R-CEL-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 24757 R-CEL-6789126 https://reactome.org/PathwayBrowser/#/R-CEL-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 24757 R-CFA-6789031 https://reactome.org/PathwayBrowser/#/R-CFA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 24757 R-CFA-6789126 https://reactome.org/PathwayBrowser/#/R-CFA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 24757 R-DDI-6789031 https://reactome.org/PathwayBrowser/#/R-DDI-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 24757 R-DDI-6789126 https://reactome.org/PathwayBrowser/#/R-DDI-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 24757 R-DME-6789031 https://reactome.org/PathwayBrowser/#/R-DME-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 24757 R-DME-6789126 https://reactome.org/PathwayBrowser/#/R-DME-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 24757 R-GGA-6789031 https://reactome.org/PathwayBrowser/#/R-GGA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 24757 R-GGA-6789126 https://reactome.org/PathwayBrowser/#/R-GGA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 24757 R-HSA-6788974 https://reactome.org/PathwayBrowser/#/R-HSA-6788974 Hypochlorous acid and nitrite react to nitryl chloride (NO2Cl) TAS Homo sapiens 24757 R-HSA-6789031 https://reactome.org/PathwayBrowser/#/R-HSA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 24757 R-HSA-6789126 https://reactome.org/PathwayBrowser/#/R-HSA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 24757 R-HSA-6789185 https://reactome.org/PathwayBrowser/#/R-HSA-6789185 Chloride ion and N-acyl group react to chloramide TAS Homo sapiens 24757 R-HSA-6789218 https://reactome.org/PathwayBrowser/#/R-HSA-6789218 Hypochlorous acid (HOCl) reacts with unsaturated lipid to form lipid chlorohydrins TAS Homo sapiens 24757 R-HSA-9625548 https://reactome.org/PathwayBrowser/#/R-HSA-9625548 Hypochlorous acid (HOCL) oxidizes Cys residues to form Cys-sulfenyl chloride TAS Homo sapiens 24757 R-HSA-9625904 https://reactome.org/PathwayBrowser/#/R-HSA-9625904 Hypochlorous acid (HOCL) reacts with Lys residue to form Lys-monochloramine TAS Homo sapiens 24757 R-HSA-9625913 https://reactome.org/PathwayBrowser/#/R-HSA-9625913 Hypochlorous acid (HOCL) reacts with Lys-monochloramine TAS Homo sapiens 24757 R-MMU-6789031 https://reactome.org/PathwayBrowser/#/R-MMU-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 24757 R-MMU-6789126 https://reactome.org/PathwayBrowser/#/R-MMU-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 24757 R-RNO-6789031 https://reactome.org/PathwayBrowser/#/R-RNO-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 24757 R-RNO-6789126 https://reactome.org/PathwayBrowser/#/R-RNO-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 24757 R-SSC-6789031 https://reactome.org/PathwayBrowser/#/R-SSC-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 24757 R-SSC-6789126 https://reactome.org/PathwayBrowser/#/R-SSC-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 2485 R-HSA-2408525 https://reactome.org/PathwayBrowser/#/R-HSA-2408525 H2SeO4 is converted to APSe by PAPSS1,2 IEA Homo sapiens 2485 R-HSA-2408540 https://reactome.org/PathwayBrowser/#/R-HSA-2408540 APSe is phosphorylated to PAPSe by PAPSS1,2 IEA Homo sapiens 2485 R-PCH-2408503 https://reactome.org/PathwayBrowser/#/R-PCH-2408503 APSe is phosphorylated to PAPSe by Kaps TAS Penicillium chrysogenum 2485 R-RNO-2408504 https://reactome.org/PathwayBrowser/#/R-RNO-2408504 H2SeO4 is converted to APSe by PAPSS1,2 TAS Rattus norvegicus 2504 R-BTA-156526 https://reactome.org/PathwayBrowser/#/R-BTA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Bos taurus 2504 R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 2504 R-BTA-5423664 https://reactome.org/PathwayBrowser/#/R-BTA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Bos taurus 2504 R-BTA-5423672 https://reactome.org/PathwayBrowser/#/R-BTA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Bos taurus 2504 R-BTA-5423678 https://reactome.org/PathwayBrowser/#/R-BTA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Bos taurus 2504 R-CEL-156526 https://reactome.org/PathwayBrowser/#/R-CEL-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Caenorhabditis elegans 2504 R-CFA-156526 https://reactome.org/PathwayBrowser/#/R-CFA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Canis familiaris 2504 R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 2504 R-CFA-5423664 https://reactome.org/PathwayBrowser/#/R-CFA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Canis familiaris 2504 R-CFA-5423672 https://reactome.org/PathwayBrowser/#/R-CFA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Canis familiaris 2504 R-DDI-156526 https://reactome.org/PathwayBrowser/#/R-DDI-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Dictyostelium discoideum 2504 R-DME-156526 https://reactome.org/PathwayBrowser/#/R-DME-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Drosophila melanogaster 2504 R-DRE-156526 https://reactome.org/PathwayBrowser/#/R-DRE-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Danio rerio 2504 R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 2504 R-DRE-5423664 https://reactome.org/PathwayBrowser/#/R-DRE-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Danio rerio 2504 R-DRE-5423672 https://reactome.org/PathwayBrowser/#/R-DRE-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Danio rerio 2504 R-DRE-5423678 https://reactome.org/PathwayBrowser/#/R-DRE-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Danio rerio 2504 R-GGA-156526 https://reactome.org/PathwayBrowser/#/R-GGA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Gallus gallus 2504 R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 2504 R-GGA-5423664 https://reactome.org/PathwayBrowser/#/R-GGA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Gallus gallus 2504 R-GGA-5423672 https://reactome.org/PathwayBrowser/#/R-GGA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Gallus gallus 2504 R-GGA-5423678 https://reactome.org/PathwayBrowser/#/R-GGA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Gallus gallus 2504 R-HSA-156526 https://reactome.org/PathwayBrowser/#/R-HSA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO TAS Homo sapiens 2504 R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 2504 R-HSA-5423664 https://reactome.org/PathwayBrowser/#/R-HSA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 TAS Homo sapiens 2504 R-HSA-5423672 https://reactome.org/PathwayBrowser/#/R-HSA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO TAS Homo sapiens 2504 R-HSA-5423678 https://reactome.org/PathwayBrowser/#/R-HSA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 TAS Homo sapiens 2504 R-MMU-156526 https://reactome.org/PathwayBrowser/#/R-MMU-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Mus musculus 2504 R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 2504 R-MMU-5423664 https://reactome.org/PathwayBrowser/#/R-MMU-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Mus musculus 2504 R-MMU-5423672 https://reactome.org/PathwayBrowser/#/R-MMU-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Mus musculus 2504 R-MMU-5423678 https://reactome.org/PathwayBrowser/#/R-MMU-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Mus musculus 2504 R-RNO-156526 https://reactome.org/PathwayBrowser/#/R-RNO-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Rattus norvegicus 2504 R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 2504 R-RNO-5423664 https://reactome.org/PathwayBrowser/#/R-RNO-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Rattus norvegicus 2504 R-RNO-5423672 https://reactome.org/PathwayBrowser/#/R-RNO-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Rattus norvegicus 2504 R-RNO-5423678 https://reactome.org/PathwayBrowser/#/R-RNO-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Rattus norvegicus 2504 R-SSC-156526 https://reactome.org/PathwayBrowser/#/R-SSC-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Sus scrofa 2504 R-SSC-213175 https://reactome.org/PathwayBrowser/#/R-SSC-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Sus scrofa 2504 R-SSC-5423664 https://reactome.org/PathwayBrowser/#/R-SSC-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Sus scrofa 2504 R-SSC-5423672 https://reactome.org/PathwayBrowser/#/R-SSC-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Sus scrofa 2504 R-SSC-5423678 https://reactome.org/PathwayBrowser/#/R-SSC-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Sus scrofa 2504 R-XTR-156526 https://reactome.org/PathwayBrowser/#/R-XTR-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 2504 R-XTR-213175 https://reactome.org/PathwayBrowser/#/R-XTR-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 2504 R-XTR-5423664 https://reactome.org/PathwayBrowser/#/R-XTR-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Xenopus tropicalis 2504 R-XTR-5423672 https://reactome.org/PathwayBrowser/#/R-XTR-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Xenopus tropicalis 2505 R-BTA-176059 https://reactome.org/PathwayBrowser/#/R-BTA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Bos taurus 2505 R-CFA-176059 https://reactome.org/PathwayBrowser/#/R-CFA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Canis familiaris 2505 R-DDI-176059 https://reactome.org/PathwayBrowser/#/R-DDI-176059 GST trimers transfer GS from GSH to luminal substrates IEA Dictyostelium discoideum 2505 R-DME-176059 https://reactome.org/PathwayBrowser/#/R-DME-176059 GST trimers transfer GS from GSH to luminal substrates IEA Drosophila melanogaster 2505 R-DRE-176059 https://reactome.org/PathwayBrowser/#/R-DRE-176059 GST trimers transfer GS from GSH to luminal substrates IEA Danio rerio 2505 R-GGA-176059 https://reactome.org/PathwayBrowser/#/R-GGA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Gallus gallus 2505 R-HSA-176059 https://reactome.org/PathwayBrowser/#/R-HSA-176059 GST trimers transfer GS from GSH to luminal substrates TAS Homo sapiens 2505 R-MMU-176059 https://reactome.org/PathwayBrowser/#/R-MMU-176059 GST trimers transfer GS from GSH to luminal substrates IEA Mus musculus 2505 R-RNO-176059 https://reactome.org/PathwayBrowser/#/R-RNO-176059 GST trimers transfer GS from GSH to luminal substrates IEA Rattus norvegicus 2505 R-SSC-176059 https://reactome.org/PathwayBrowser/#/R-SSC-176059 GST trimers transfer GS from GSH to luminal substrates IEA Sus scrofa 2505 R-XTR-176059 https://reactome.org/PathwayBrowser/#/R-XTR-176059 GST trimers transfer GS from GSH to luminal substrates IEA Xenopus tropicalis 251408 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 251408 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 251408 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 251408 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 251408 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 251408 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 251408 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 251408 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 251408 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 251408 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 251408 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 251408 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 251408 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 251408 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 251408 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 25372 R-BTA-1614544 https://reactome.org/PathwayBrowser/#/R-BTA-1614544 Sulfite is oxidized to sulfate IEA Bos taurus 25372 R-BTA-947499 https://reactome.org/PathwayBrowser/#/R-BTA-947499 Exchange of oxygen with sulfur in MoCo IEA Bos taurus 25372 R-BTA-947531 https://reactome.org/PathwayBrowser/#/R-BTA-947531 Molybdenum ion transfer onto molybdopterin IEA Bos taurus 25372 R-CEL-1614544 https://reactome.org/PathwayBrowser/#/R-CEL-1614544 Sulfite is oxidized to sulfate IEA Caenorhabditis elegans 25372 R-CEL-947499 https://reactome.org/PathwayBrowser/#/R-CEL-947499 Exchange of oxygen with sulfur in MoCo IEA Caenorhabditis elegans 25372 R-CEL-947531 https://reactome.org/PathwayBrowser/#/R-CEL-947531 Molybdenum ion transfer onto molybdopterin IEA Caenorhabditis elegans 25372 R-CFA-1614544 https://reactome.org/PathwayBrowser/#/R-CFA-1614544 Sulfite is oxidized to sulfate IEA Canis familiaris 25372 R-CFA-947499 https://reactome.org/PathwayBrowser/#/R-CFA-947499 Exchange of oxygen with sulfur in MoCo IEA Canis familiaris 25372 R-CFA-947531 https://reactome.org/PathwayBrowser/#/R-CFA-947531 Molybdenum ion transfer onto molybdopterin IEA Canis familiaris 25372 R-DDI-1614544 https://reactome.org/PathwayBrowser/#/R-DDI-1614544 Sulfite is oxidized to sulfate IEA Dictyostelium discoideum 25372 R-DDI-947499 https://reactome.org/PathwayBrowser/#/R-DDI-947499 Exchange of oxygen with sulfur in MoCo IEA Dictyostelium discoideum 25372 R-DDI-947531 https://reactome.org/PathwayBrowser/#/R-DDI-947531 Molybdenum ion transfer onto molybdopterin IEA Dictyostelium discoideum 25372 R-DME-1614544 https://reactome.org/PathwayBrowser/#/R-DME-1614544 Sulfite is oxidized to sulfate IEA Drosophila melanogaster 25372 R-DME-947499 https://reactome.org/PathwayBrowser/#/R-DME-947499 Exchange of oxygen with sulfur in MoCo IEA Drosophila melanogaster 25372 R-DME-947531 https://reactome.org/PathwayBrowser/#/R-DME-947531 Molybdenum ion transfer onto molybdopterin IEA Drosophila melanogaster 25372 R-DRE-947499 https://reactome.org/PathwayBrowser/#/R-DRE-947499 Exchange of oxygen with sulfur in MoCo IEA Danio rerio 25372 R-GGA-1614544 https://reactome.org/PathwayBrowser/#/R-GGA-1614544 Sulfite is oxidized to sulfate IEA Gallus gallus 25372 R-GGA-947499 https://reactome.org/PathwayBrowser/#/R-GGA-947499 Exchange of oxygen with sulfur in MoCo IEA Gallus gallus 25372 R-GGA-947531 https://reactome.org/PathwayBrowser/#/R-GGA-947531 Molybdenum ion transfer onto molybdopterin IEA Gallus gallus 25372 R-HSA-1614544 https://reactome.org/PathwayBrowser/#/R-HSA-1614544 Sulfite is oxidized to sulfate TAS Homo sapiens 25372 R-HSA-947499 https://reactome.org/PathwayBrowser/#/R-HSA-947499 Exchange of oxygen with sulfur in MoCo TAS Homo sapiens 25372 R-HSA-947531 https://reactome.org/PathwayBrowser/#/R-HSA-947531 Molybdenum ion transfer onto molybdopterin TAS Homo sapiens 25372 R-MMU-1614544 https://reactome.org/PathwayBrowser/#/R-MMU-1614544 Sulfite is oxidized to sulfate IEA Mus musculus 25372 R-MMU-947499 https://reactome.org/PathwayBrowser/#/R-MMU-947499 Exchange of oxygen with sulfur in MoCo IEA Mus musculus 25372 R-MMU-947531 https://reactome.org/PathwayBrowser/#/R-MMU-947531 Molybdenum ion transfer onto molybdopterin IEA Mus musculus 25372 R-RNO-1614544 https://reactome.org/PathwayBrowser/#/R-RNO-1614544 Sulfite is oxidized to sulfate IEA Rattus norvegicus 25372 R-RNO-947499 https://reactome.org/PathwayBrowser/#/R-RNO-947499 Exchange of oxygen with sulfur in MoCo IEA Rattus norvegicus 25372 R-RNO-947531 https://reactome.org/PathwayBrowser/#/R-RNO-947531 Molybdenum ion transfer onto molybdopterin IEA Rattus norvegicus 25372 R-SSC-1614544 https://reactome.org/PathwayBrowser/#/R-SSC-1614544 Sulfite is oxidized to sulfate IEA Sus scrofa 25372 R-SSC-947499 https://reactome.org/PathwayBrowser/#/R-SSC-947499 Exchange of oxygen with sulfur in MoCo IEA Sus scrofa 25372 R-SSC-947531 https://reactome.org/PathwayBrowser/#/R-SSC-947531 Molybdenum ion transfer onto molybdopterin IEA Sus scrofa 25372 R-XTR-1614544 https://reactome.org/PathwayBrowser/#/R-XTR-1614544 Sulfite is oxidized to sulfate IEA Xenopus tropicalis 25567 R-HSA-6803998 https://reactome.org/PathwayBrowser/#/R-HSA-6803998 Nitrite ion and HNO2 form a conjugated acid-base pair TAS Homo sapiens 25567 R-HSA-6803999 https://reactome.org/PathwayBrowser/#/R-HSA-6803999 HNO2 produces N2O3 TAS Homo sapiens 25609 R-HSA-9683669 https://reactome.org/PathwayBrowser/#/R-HSA-9683669 E protein gets N-glycosylated TAS Homo sapiens 25609 R-HSA-9683751 https://reactome.org/PathwayBrowser/#/R-HSA-9683751 M protein gets N-glycosylated TAS Homo sapiens 25609 R-HSA-9683755 https://reactome.org/PathwayBrowser/#/R-HSA-9683755 Spike protein gets N-glycosylated TAS Homo sapiens 25609 R-HSA-9684261 https://reactome.org/PathwayBrowser/#/R-HSA-9684261 nsp4 is glycosylated TAS Homo sapiens 25609 R-HSA-9684275 https://reactome.org/PathwayBrowser/#/R-HSA-9684275 nsp3-4 is glycosylated TAS Homo sapiens 25609 R-HSA-9684290 https://reactome.org/PathwayBrowser/#/R-HSA-9684290 nsp3 is glycosylated TAS Homo sapiens 25609 R-HSA-9694331 https://reactome.org/PathwayBrowser/#/R-HSA-9694331 nsp3-4 is glycosylated IEA Homo sapiens 25609 R-HSA-9694389 https://reactome.org/PathwayBrowser/#/R-HSA-9694389 nsp3 is glycosylated IEA Homo sapiens 25609 R-HSA-9694525 https://reactome.org/PathwayBrowser/#/R-HSA-9694525 M protein gets N-glycosylated IEA Homo sapiens 25609 R-HSA-9694611 https://reactome.org/PathwayBrowser/#/R-HSA-9694611 nsp4 is glycosylated IEA Homo sapiens 25609 R-HSA-9694790 https://reactome.org/PathwayBrowser/#/R-HSA-9694790 E protein gets N-glycosylated IEA Homo sapiens 25667 R-BTA-2404137 https://reactome.org/PathwayBrowser/#/R-BTA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 25667 R-BTA-2453855 https://reactome.org/PathwayBrowser/#/R-BTA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 25667 R-BTA-975608 https://reactome.org/PathwayBrowser/#/R-BTA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Bos taurus 25667 R-CFA-2404137 https://reactome.org/PathwayBrowser/#/R-CFA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 25667 R-CFA-2453855 https://reactome.org/PathwayBrowser/#/R-CFA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 25667 R-CFA-975608 https://reactome.org/PathwayBrowser/#/R-CFA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Canis familiaris 25667 R-DRE-2404137 https://reactome.org/PathwayBrowser/#/R-DRE-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 25667 R-DRE-2453855 https://reactome.org/PathwayBrowser/#/R-DRE-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 25667 R-DRE-975608 https://reactome.org/PathwayBrowser/#/R-DRE-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Danio rerio 25667 R-GGA-2404137 https://reactome.org/PathwayBrowser/#/R-GGA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 25667 R-GGA-2453855 https://reactome.org/PathwayBrowser/#/R-GGA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 25667 R-GGA-975608 https://reactome.org/PathwayBrowser/#/R-GGA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Gallus gallus 25667 R-HSA-2404137 https://reactome.org/PathwayBrowser/#/R-HSA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 25667 R-HSA-2453855 https://reactome.org/PathwayBrowser/#/R-HSA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 25667 R-HSA-2466710 https://reactome.org/PathwayBrowser/#/R-HSA-2466710 Defective LRAT does not esterify RBP1:atROL and FACYLs to atREs TAS Homo sapiens 25667 R-HSA-975608 https://reactome.org/PathwayBrowser/#/R-HSA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs TAS Homo sapiens 25667 R-MMU-2404137 https://reactome.org/PathwayBrowser/#/R-MMU-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 25667 R-MMU-2453855 https://reactome.org/PathwayBrowser/#/R-MMU-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 25667 R-MMU-975608 https://reactome.org/PathwayBrowser/#/R-MMU-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Mus musculus 25667 R-RNO-2404137 https://reactome.org/PathwayBrowser/#/R-RNO-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 25667 R-RNO-2453855 https://reactome.org/PathwayBrowser/#/R-RNO-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 25667 R-RNO-975608 https://reactome.org/PathwayBrowser/#/R-RNO-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Rattus norvegicus 25667 R-SSC-2404137 https://reactome.org/PathwayBrowser/#/R-SSC-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 25667 R-SSC-2453855 https://reactome.org/PathwayBrowser/#/R-SSC-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 25667 R-SSC-975608 https://reactome.org/PathwayBrowser/#/R-SSC-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Sus scrofa 25667 R-XTR-2404137 https://reactome.org/PathwayBrowser/#/R-XTR-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 25667 R-XTR-2453855 https://reactome.org/PathwayBrowser/#/R-XTR-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 25667 R-XTR-975608 https://reactome.org/PathwayBrowser/#/R-XTR-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Xenopus tropicalis 2567 R-CEL-9717841 https://reactome.org/PathwayBrowser/#/R-CEL-9717841 holo-FDPS dimer binds NBPs IEA Caenorhabditis elegans 2567 R-CFA-9717841 https://reactome.org/PathwayBrowser/#/R-CFA-9717841 holo-FDPS dimer binds NBPs IEA Canis familiaris 2567 R-DDI-9717841 https://reactome.org/PathwayBrowser/#/R-DDI-9717841 holo-FDPS dimer binds NBPs IEA Dictyostelium discoideum 2567 R-DME-9717841 https://reactome.org/PathwayBrowser/#/R-DME-9717841 holo-FDPS dimer binds NBPs IEA Drosophila melanogaster 2567 R-DRE-9717841 https://reactome.org/PathwayBrowser/#/R-DRE-9717841 holo-FDPS dimer binds NBPs IEA Danio rerio 2567 R-GGA-9717841 https://reactome.org/PathwayBrowser/#/R-GGA-9717841 holo-FDPS dimer binds NBPs IEA Gallus gallus 2567 R-HSA-9717841 https://reactome.org/PathwayBrowser/#/R-HSA-9717841 holo-FDPS dimer binds NBPs TAS Homo sapiens 2567 R-MMU-9717841 https://reactome.org/PathwayBrowser/#/R-MMU-9717841 holo-FDPS dimer binds NBPs IEA Mus musculus 2567 R-PFA-9717841 https://reactome.org/PathwayBrowser/#/R-PFA-9717841 holo-FDPS dimer binds NBPs IEA Plasmodium falciparum 2567 R-RNO-9717841 https://reactome.org/PathwayBrowser/#/R-RNO-9717841 holo-FDPS dimer binds NBPs IEA Rattus norvegicus 2567 R-SCE-9717841 https://reactome.org/PathwayBrowser/#/R-SCE-9717841 holo-FDPS dimer binds NBPs IEA Saccharomyces cerevisiae 2567 R-SPO-9717841 https://reactome.org/PathwayBrowser/#/R-SPO-9717841 holo-FDPS dimer binds NBPs IEA Schizosaccharomyces pombe 2567 R-SSC-9717841 https://reactome.org/PathwayBrowser/#/R-SSC-9717841 holo-FDPS dimer binds NBPs IEA Sus scrofa 25676 R-BTA-1236943 https://reactome.org/PathwayBrowser/#/R-BTA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Bos taurus 25676 R-BTA-1236954 https://reactome.org/PathwayBrowser/#/R-BTA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Bos taurus 25676 R-BTA-1236964 https://reactome.org/PathwayBrowser/#/R-BTA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Bos taurus 25676 R-BTA-1236970 https://reactome.org/PathwayBrowser/#/R-BTA-1236970 Proteasomal clevage of exogenous antigen IEA Bos taurus 25676 R-BTA-8940641 https://reactome.org/PathwayBrowser/#/R-BTA-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) IEA Bos taurus 25676 R-BTA-8951499 https://reactome.org/PathwayBrowser/#/R-BTA-8951499 Loading of antigenic peptides on to class I MHC IEA Bos taurus 25676 R-BTA-983138 https://reactome.org/PathwayBrowser/#/R-BTA-983138 Transport of MHC heterotrimer to ER exit site IEA Bos taurus 25676 R-BTA-983144 https://reactome.org/PathwayBrowser/#/R-BTA-983144 Transport of Antigen peptide in to ER IEA Bos taurus 25676 R-BTA-983150 https://reactome.org/PathwayBrowser/#/R-BTA-983150 Proteasomal cleavage of substrate IEA Bos taurus 25676 R-BTA-983158 https://reactome.org/PathwayBrowser/#/R-BTA-983158 Trimming of peptides in ER IEA Bos taurus 25676 R-BTA-983161 https://reactome.org/PathwayBrowser/#/R-BTA-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Bos taurus 25676 R-BTA-983162 https://reactome.org/PathwayBrowser/#/R-BTA-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Bos taurus 25676 R-BTA-983424 https://reactome.org/PathwayBrowser/#/R-BTA-983424 Budding of COPII coated vesicle IEA Bos taurus 25676 R-BTA-983425 https://reactome.org/PathwayBrowser/#/R-BTA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Bos taurus 25676 R-CEL-1236970 https://reactome.org/PathwayBrowser/#/R-CEL-1236970 Proteasomal clevage of exogenous antigen IEA Caenorhabditis elegans 25676 R-CEL-983144 https://reactome.org/PathwayBrowser/#/R-CEL-983144 Transport of Antigen peptide in to ER IEA Caenorhabditis elegans 25676 R-CEL-983150 https://reactome.org/PathwayBrowser/#/R-CEL-983150 Proteasomal cleavage of substrate IEA Caenorhabditis elegans 25676 R-CEL-983158 https://reactome.org/PathwayBrowser/#/R-CEL-983158 Trimming of peptides in ER IEA Caenorhabditis elegans 25676 R-CEL-983162 https://reactome.org/PathwayBrowser/#/R-CEL-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Caenorhabditis elegans 25676 R-CFA-1236943 https://reactome.org/PathwayBrowser/#/R-CFA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Canis familiaris 25676 R-CFA-1236954 https://reactome.org/PathwayBrowser/#/R-CFA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Canis familiaris 25676 R-CFA-1236964 https://reactome.org/PathwayBrowser/#/R-CFA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Canis familiaris 25676 R-CFA-1236970 https://reactome.org/PathwayBrowser/#/R-CFA-1236970 Proteasomal clevage of exogenous antigen IEA Canis familiaris 25676 R-CFA-8940641 https://reactome.org/PathwayBrowser/#/R-CFA-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) IEA Canis familiaris 25676 R-CFA-8951499 https://reactome.org/PathwayBrowser/#/R-CFA-8951499 Loading of antigenic peptides on to class I MHC IEA Canis familiaris 25676 R-CFA-983138 https://reactome.org/PathwayBrowser/#/R-CFA-983138 Transport of MHC heterotrimer to ER exit site IEA Canis familiaris 25676 R-CFA-983150 https://reactome.org/PathwayBrowser/#/R-CFA-983150 Proteasomal cleavage of substrate IEA Canis familiaris 25676 R-CFA-983158 https://reactome.org/PathwayBrowser/#/R-CFA-983158 Trimming of peptides in ER IEA Canis familiaris 25676 R-CFA-983162 https://reactome.org/PathwayBrowser/#/R-CFA-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Canis familiaris 25676 R-CFA-983424 https://reactome.org/PathwayBrowser/#/R-CFA-983424 Budding of COPII coated vesicle IEA Canis familiaris 25676 R-CFA-983425 https://reactome.org/PathwayBrowser/#/R-CFA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Canis familiaris 25676 R-DDI-1236970 https://reactome.org/PathwayBrowser/#/R-DDI-1236970 Proteasomal clevage of exogenous antigen IEA Dictyostelium discoideum 25676 R-DDI-8940641 https://reactome.org/PathwayBrowser/#/R-DDI-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) IEA Dictyostelium discoideum 25676 R-DDI-983150 https://reactome.org/PathwayBrowser/#/R-DDI-983150 Proteasomal cleavage of substrate IEA Dictyostelium discoideum 25676 R-DDI-983158 https://reactome.org/PathwayBrowser/#/R-DDI-983158 Trimming of peptides in ER IEA Dictyostelium discoideum 25676 R-DDI-983162 https://reactome.org/PathwayBrowser/#/R-DDI-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Dictyostelium discoideum 25676 R-DME-1236970 https://reactome.org/PathwayBrowser/#/R-DME-1236970 Proteasomal clevage of exogenous antigen IEA Drosophila melanogaster 25676 R-DME-983150 https://reactome.org/PathwayBrowser/#/R-DME-983150 Proteasomal cleavage of substrate IEA Drosophila melanogaster 25676 R-DME-983158 https://reactome.org/PathwayBrowser/#/R-DME-983158 Trimming of peptides in ER IEA Drosophila melanogaster 25676 R-DME-983162 https://reactome.org/PathwayBrowser/#/R-DME-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Drosophila melanogaster 25676 R-DRE-1236943 https://reactome.org/PathwayBrowser/#/R-DRE-1236943 Loading of antigen peptide onto MHC class I molecule IEA Danio rerio 25676 R-DRE-1236964 https://reactome.org/PathwayBrowser/#/R-DRE-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Danio rerio 25676 R-DRE-1236970 https://reactome.org/PathwayBrowser/#/R-DRE-1236970 Proteasomal clevage of exogenous antigen IEA Danio rerio 25676 R-DRE-8951499 https://reactome.org/PathwayBrowser/#/R-DRE-8951499 Loading of antigenic peptides on to class I MHC IEA Danio rerio 25676 R-DRE-983138 https://reactome.org/PathwayBrowser/#/R-DRE-983138 Transport of MHC heterotrimer to ER exit site IEA Danio rerio 25676 R-DRE-983150 https://reactome.org/PathwayBrowser/#/R-DRE-983150 Proteasomal cleavage of substrate IEA Danio rerio 25676 R-DRE-983162 https://reactome.org/PathwayBrowser/#/R-DRE-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Danio rerio 25676 R-DRE-983424 https://reactome.org/PathwayBrowser/#/R-DRE-983424 Budding of COPII coated vesicle IEA Danio rerio 25676 R-DRE-983425 https://reactome.org/PathwayBrowser/#/R-DRE-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Danio rerio 25676 R-GGA-1236943 https://reactome.org/PathwayBrowser/#/R-GGA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Gallus gallus 25676 R-GGA-1236954 https://reactome.org/PathwayBrowser/#/R-GGA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Gallus gallus 25676 R-GGA-1236964 https://reactome.org/PathwayBrowser/#/R-GGA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Gallus gallus 25676 R-GGA-8940641 https://reactome.org/PathwayBrowser/#/R-GGA-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) IEA Gallus gallus 25676 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus 25676 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus 25676 R-GGA-983158 https://reactome.org/PathwayBrowser/#/R-GGA-983158 Trimming of peptides in ER IEA Gallus gallus 25676 R-GGA-983162 https://reactome.org/PathwayBrowser/#/R-GGA-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Gallus gallus 25676 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus 25676 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus 25676 R-HSA-1236935 https://reactome.org/PathwayBrowser/#/R-HSA-1236935 Proteasomal cleavage of substrate IEA Homo sapiens 25676 R-HSA-1236943 https://reactome.org/PathwayBrowser/#/R-HSA-1236943 Loading of antigen peptide onto MHC class I molecule TAS Homo sapiens 25676 R-HSA-1236948 https://reactome.org/PathwayBrowser/#/R-HSA-1236948 Antigen processing by cathepsin S in endosoytic vesicle IEA Homo sapiens 25676 R-HSA-1236949 https://reactome.org/PathwayBrowser/#/R-HSA-1236949 Translocation of antigenic peptides back to phagosomes via TAP IEA Homo sapiens 25676 R-HSA-1236954 https://reactome.org/PathwayBrowser/#/R-HSA-1236954 Trimming of peptides by IRAP in endocytic vesicles TAS Homo sapiens 25676 R-HSA-1236964 https://reactome.org/PathwayBrowser/#/R-HSA-1236964 Translocation of peptide bound MHC class I complex to cell surface TAS Homo sapiens 25676 R-HSA-1236970 https://reactome.org/PathwayBrowser/#/R-HSA-1236970 Proteasomal clevage of exogenous antigen TAS Homo sapiens 25676 R-HSA-8940641 https://reactome.org/PathwayBrowser/#/R-HSA-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) TAS Homo sapiens 25676 R-HSA-8951499 https://reactome.org/PathwayBrowser/#/R-HSA-8951499 Loading of antigenic peptides on to class I MHC TAS Homo sapiens 25676 R-HSA-9755328 https://reactome.org/PathwayBrowser/#/R-HSA-9755328 SARS-CoV-2 8 binds class I MHC TAS Homo sapiens 25676 R-HSA-9755359 https://reactome.org/PathwayBrowser/#/R-HSA-9755359 SARS-CoV-2 8:class I MHC binds BECN1 TAS Homo sapiens 25676 R-HSA-983138 https://reactome.org/PathwayBrowser/#/R-HSA-983138 Transport of MHC heterotrimer to ER exit site TAS Homo sapiens 25676 R-HSA-983144 https://reactome.org/PathwayBrowser/#/R-HSA-983144 Transport of Antigen peptide in to ER TAS Homo sapiens 25676 R-HSA-983150 https://reactome.org/PathwayBrowser/#/R-HSA-983150 Proteasomal cleavage of substrate TAS Homo sapiens 25676 R-HSA-983158 https://reactome.org/PathwayBrowser/#/R-HSA-983158 Trimming of peptides in ER TAS Homo sapiens 25676 R-HSA-983161 https://reactome.org/PathwayBrowser/#/R-HSA-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex TAS Homo sapiens 25676 R-HSA-983162 https://reactome.org/PathwayBrowser/#/R-HSA-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases TAS Homo sapiens 25676 R-HSA-983424 https://reactome.org/PathwayBrowser/#/R-HSA-983424 Budding of COPII coated vesicle TAS Homo sapiens 25676 R-HSA-983425 https://reactome.org/PathwayBrowser/#/R-HSA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle TAS Homo sapiens 25676 R-HSA-983426 https://reactome.org/PathwayBrowser/#/R-HSA-983426 Capturing cargo and formation of prebudding complex TAS Homo sapiens 25676 R-MMU-1236943 https://reactome.org/PathwayBrowser/#/R-MMU-1236943 Loading of antigen peptide onto MHC class I molecule IEA Mus musculus 25676 R-MMU-1236954 https://reactome.org/PathwayBrowser/#/R-MMU-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Mus musculus 25676 R-MMU-1236964 https://reactome.org/PathwayBrowser/#/R-MMU-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Mus musculus 25676 R-MMU-1236970 https://reactome.org/PathwayBrowser/#/R-MMU-1236970 Proteasomal clevage of exogenous antigen IEA Mus musculus 25676 R-MMU-8940641 https://reactome.org/PathwayBrowser/#/R-MMU-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) IEA Mus musculus 25676 R-MMU-8951499 https://reactome.org/PathwayBrowser/#/R-MMU-8951499 Loading of antigenic peptides on to class I MHC IEA Mus musculus 25676 R-MMU-983138 https://reactome.org/PathwayBrowser/#/R-MMU-983138 Transport of MHC heterotrimer to ER exit site IEA Mus musculus 25676 R-MMU-983144 https://reactome.org/PathwayBrowser/#/R-MMU-983144 Transport of Antigen peptide in to ER IEA Mus musculus 25676 R-MMU-983150 https://reactome.org/PathwayBrowser/#/R-MMU-983150 Proteasomal cleavage of substrate IEA Mus musculus 25676 R-MMU-983158 https://reactome.org/PathwayBrowser/#/R-MMU-983158 Trimming of peptides in ER IEA Mus musculus 25676 R-MMU-983161 https://reactome.org/PathwayBrowser/#/R-MMU-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Mus musculus 25676 R-MMU-983162 https://reactome.org/PathwayBrowser/#/R-MMU-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Mus musculus 25676 R-MMU-983424 https://reactome.org/PathwayBrowser/#/R-MMU-983424 Budding of COPII coated vesicle IEA Mus musculus 25676 R-MMU-983425 https://reactome.org/PathwayBrowser/#/R-MMU-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Mus musculus 25676 R-PFA-1236970 https://reactome.org/PathwayBrowser/#/R-PFA-1236970 Proteasomal clevage of exogenous antigen IEA Plasmodium falciparum 25676 R-PFA-983150 https://reactome.org/PathwayBrowser/#/R-PFA-983150 Proteasomal cleavage of substrate IEA Plasmodium falciparum 25676 R-RNO-1236943 https://reactome.org/PathwayBrowser/#/R-RNO-1236943 Loading of antigen peptide onto MHC class I molecule IEA Rattus norvegicus 25676 R-RNO-1236954 https://reactome.org/PathwayBrowser/#/R-RNO-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Rattus norvegicus 25676 R-RNO-1236964 https://reactome.org/PathwayBrowser/#/R-RNO-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Rattus norvegicus 25676 R-RNO-1236970 https://reactome.org/PathwayBrowser/#/R-RNO-1236970 Proteasomal clevage of exogenous antigen IEA Rattus norvegicus 25676 R-RNO-8940641 https://reactome.org/PathwayBrowser/#/R-RNO-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) IEA Rattus norvegicus 25676 R-RNO-8951499 https://reactome.org/PathwayBrowser/#/R-RNO-8951499 Loading of antigenic peptides on to class I MHC IEA Rattus norvegicus 25676 R-RNO-983138 https://reactome.org/PathwayBrowser/#/R-RNO-983138 Transport of MHC heterotrimer to ER exit site IEA Rattus norvegicus 25676 R-RNO-983144 https://reactome.org/PathwayBrowser/#/R-RNO-983144 Transport of Antigen peptide in to ER IEA Rattus norvegicus 25676 R-RNO-983150 https://reactome.org/PathwayBrowser/#/R-RNO-983150 Proteasomal cleavage of substrate IEA Rattus norvegicus 25676 R-RNO-983158 https://reactome.org/PathwayBrowser/#/R-RNO-983158 Trimming of peptides in ER IEA Rattus norvegicus 25676 R-RNO-983161 https://reactome.org/PathwayBrowser/#/R-RNO-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Rattus norvegicus 25676 R-RNO-983162 https://reactome.org/PathwayBrowser/#/R-RNO-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Rattus norvegicus 25676 R-RNO-983424 https://reactome.org/PathwayBrowser/#/R-RNO-983424 Budding of COPII coated vesicle IEA Rattus norvegicus 25676 R-RNO-983425 https://reactome.org/PathwayBrowser/#/R-RNO-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Rattus norvegicus 25676 R-SCE-1236970 https://reactome.org/PathwayBrowser/#/R-SCE-1236970 Proteasomal clevage of exogenous antigen IEA Saccharomyces cerevisiae 25676 R-SCE-8940641 https://reactome.org/PathwayBrowser/#/R-SCE-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) IEA Saccharomyces cerevisiae 25676 R-SCE-983150 https://reactome.org/PathwayBrowser/#/R-SCE-983150 Proteasomal cleavage of substrate IEA Saccharomyces cerevisiae 25676 R-SCE-983162 https://reactome.org/PathwayBrowser/#/R-SCE-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Saccharomyces cerevisiae 25676 R-SPO-1236970 https://reactome.org/PathwayBrowser/#/R-SPO-1236970 Proteasomal clevage of exogenous antigen IEA Schizosaccharomyces pombe 25676 R-SPO-983144 https://reactome.org/PathwayBrowser/#/R-SPO-983144 Transport of Antigen peptide in to ER IEA Schizosaccharomyces pombe 25676 R-SPO-983150 https://reactome.org/PathwayBrowser/#/R-SPO-983150 Proteasomal cleavage of substrate IEA Schizosaccharomyces pombe 25676 R-SPO-983162 https://reactome.org/PathwayBrowser/#/R-SPO-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Schizosaccharomyces pombe 25676 R-SSC-1236943 https://reactome.org/PathwayBrowser/#/R-SSC-1236943 Loading of antigen peptide onto MHC class I molecule IEA Sus scrofa 25676 R-SSC-1236954 https://reactome.org/PathwayBrowser/#/R-SSC-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Sus scrofa 25676 R-SSC-1236964 https://reactome.org/PathwayBrowser/#/R-SSC-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Sus scrofa 25676 R-SSC-1236970 https://reactome.org/PathwayBrowser/#/R-SSC-1236970 Proteasomal clevage of exogenous antigen IEA Sus scrofa 25676 R-SSC-8940641 https://reactome.org/PathwayBrowser/#/R-SSC-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) IEA Sus scrofa 25676 R-SSC-8951499 https://reactome.org/PathwayBrowser/#/R-SSC-8951499 Loading of antigenic peptides on to class I MHC IEA Sus scrofa 25676 R-SSC-983138 https://reactome.org/PathwayBrowser/#/R-SSC-983138 Transport of MHC heterotrimer to ER exit site IEA Sus scrofa 25676 R-SSC-983144 https://reactome.org/PathwayBrowser/#/R-SSC-983144 Transport of Antigen peptide in to ER IEA Sus scrofa 25676 R-SSC-983150 https://reactome.org/PathwayBrowser/#/R-SSC-983150 Proteasomal cleavage of substrate IEA Sus scrofa 25676 R-SSC-983158 https://reactome.org/PathwayBrowser/#/R-SSC-983158 Trimming of peptides in ER IEA Sus scrofa 25676 R-SSC-983161 https://reactome.org/PathwayBrowser/#/R-SSC-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Sus scrofa 25676 R-SSC-983162 https://reactome.org/PathwayBrowser/#/R-SSC-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Sus scrofa 25676 R-SSC-983424 https://reactome.org/PathwayBrowser/#/R-SSC-983424 Budding of COPII coated vesicle IEA Sus scrofa 25676 R-SSC-983425 https://reactome.org/PathwayBrowser/#/R-SSC-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Sus scrofa 25676 R-XTR-8940641 https://reactome.org/PathwayBrowser/#/R-XTR-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) IEA Xenopus tropicalis 25676 R-XTR-983158 https://reactome.org/PathwayBrowser/#/R-XTR-983158 Trimming of peptides in ER IEA Xenopus tropicalis 25676 R-XTR-983162 https://reactome.org/PathwayBrowser/#/R-XTR-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Xenopus tropicalis 25676 R-XTR-983424 https://reactome.org/PathwayBrowser/#/R-XTR-983424 Budding of COPII coated vesicle IEA Xenopus tropicalis 25676 R-XTR-983425 https://reactome.org/PathwayBrowser/#/R-XTR-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Xenopus tropicalis 25696 R-BTA-1454916 https://reactome.org/PathwayBrowser/#/R-BTA-1454916 The ABCC family mediates organic anion transport IEA Bos taurus 25696 R-BTA-372449 https://reactome.org/PathwayBrowser/#/R-BTA-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Bos taurus 25696 R-CEL-1454916 https://reactome.org/PathwayBrowser/#/R-CEL-1454916 The ABCC family mediates organic anion transport IEA Caenorhabditis elegans 25696 R-CEL-372449 https://reactome.org/PathwayBrowser/#/R-CEL-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Caenorhabditis elegans 25696 R-CFA-1454916 https://reactome.org/PathwayBrowser/#/R-CFA-1454916 The ABCC family mediates organic anion transport IEA Canis familiaris 25696 R-CFA-372449 https://reactome.org/PathwayBrowser/#/R-CFA-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Canis familiaris 25696 R-DDI-1454916 https://reactome.org/PathwayBrowser/#/R-DDI-1454916 The ABCC family mediates organic anion transport IEA Dictyostelium discoideum 25696 R-DME-1454916 https://reactome.org/PathwayBrowser/#/R-DME-1454916 The ABCC family mediates organic anion transport IEA Drosophila melanogaster 25696 R-DME-372449 https://reactome.org/PathwayBrowser/#/R-DME-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Drosophila melanogaster 25696 R-DRE-1454916 https://reactome.org/PathwayBrowser/#/R-DRE-1454916 The ABCC family mediates organic anion transport IEA Danio rerio 25696 R-DRE-372449 https://reactome.org/PathwayBrowser/#/R-DRE-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Danio rerio 25696 R-GGA-1454916 https://reactome.org/PathwayBrowser/#/R-GGA-1454916 The ABCC family mediates organic anion transport IEA Gallus gallus 25696 R-GGA-372449 https://reactome.org/PathwayBrowser/#/R-GGA-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Gallus gallus 25696 R-HSA-1454916 https://reactome.org/PathwayBrowser/#/R-HSA-1454916 The ABCC family mediates organic anion transport TAS Homo sapiens 25696 R-HSA-372449 https://reactome.org/PathwayBrowser/#/R-HSA-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion TAS Homo sapiens 25696 R-HSA-5690340 https://reactome.org/PathwayBrowser/#/R-HSA-5690340 Defective ABCC6 does not transport organic anion from cytosol to extracellular region TAS Homo sapiens 25696 R-MMU-1454916 https://reactome.org/PathwayBrowser/#/R-MMU-1454916 The ABCC family mediates organic anion transport IEA Mus musculus 25696 R-MMU-372449 https://reactome.org/PathwayBrowser/#/R-MMU-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Mus musculus 25696 R-PFA-1454916 https://reactome.org/PathwayBrowser/#/R-PFA-1454916 The ABCC family mediates organic anion transport IEA Plasmodium falciparum 25696 R-RNO-1454916 https://reactome.org/PathwayBrowser/#/R-RNO-1454916 The ABCC family mediates organic anion transport IEA Rattus norvegicus 25696 R-RNO-372449 https://reactome.org/PathwayBrowser/#/R-RNO-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Rattus norvegicus 25696 R-SCE-1454916 https://reactome.org/PathwayBrowser/#/R-SCE-1454916 The ABCC family mediates organic anion transport IEA Saccharomyces cerevisiae 25696 R-SCE-372449 https://reactome.org/PathwayBrowser/#/R-SCE-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Saccharomyces cerevisiae 25696 R-SPO-1454916 https://reactome.org/PathwayBrowser/#/R-SPO-1454916 The ABCC family mediates organic anion transport IEA Schizosaccharomyces pombe 25696 R-SPO-372449 https://reactome.org/PathwayBrowser/#/R-SPO-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Schizosaccharomyces pombe 25696 R-SSC-1454916 https://reactome.org/PathwayBrowser/#/R-SSC-1454916 The ABCC family mediates organic anion transport IEA Sus scrofa 25696 R-SSC-372449 https://reactome.org/PathwayBrowser/#/R-SSC-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Sus scrofa 25696 R-XTR-1454916 https://reactome.org/PathwayBrowser/#/R-XTR-1454916 The ABCC family mediates organic anion transport IEA Xenopus tropicalis 25696 R-XTR-372449 https://reactome.org/PathwayBrowser/#/R-XTR-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Xenopus tropicalis 258351 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 258351 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 258351 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 258351 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 258351 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 258351 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 258351 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 258351 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 258351 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 258351 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 258351 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 258351 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 258351 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 258351 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 258351 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 258351 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 258351 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 258351 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 258351 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 258351 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 258351 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 258351 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 258351 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 258351 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 258351 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 258351 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 258351 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 258351 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 258351 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 258351 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 258351 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 258351 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 258351 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 258351 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 258351 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 258351 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 258351 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 25858 R-BTA-174967 https://reactome.org/PathwayBrowser/#/R-BTA-174967 NAT2 acetylation IEA Bos taurus 25858 R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 25858 R-DRE-174967 https://reactome.org/PathwayBrowser/#/R-DRE-174967 NAT2 acetylation IEA Danio rerio 25858 R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 25858 R-GGA-174967 https://reactome.org/PathwayBrowser/#/R-GGA-174967 NAT2 acetylation IEA Gallus gallus 25858 R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 25858 R-HSA-174967 https://reactome.org/PathwayBrowser/#/R-HSA-174967 NAT2 acetylation TAS Homo sapiens 25858 R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 25858 R-MMU-174967 https://reactome.org/PathwayBrowser/#/R-MMU-174967 NAT2 acetylation IEA Mus musculus 25858 R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 25858 R-RNO-174967 https://reactome.org/PathwayBrowser/#/R-RNO-174967 NAT2 acetylation IEA Rattus norvegicus 25858 R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 25858 R-SSC-174967 https://reactome.org/PathwayBrowser/#/R-SSC-174967 NAT2 acetylation IEA Sus scrofa 25858 R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 25935 R-HSA-1222342 https://reactome.org/PathwayBrowser/#/R-HSA-1222342 Hydroperoxyl enters the bacterium TAS Homo sapiens 25935 R-HSA-1222353 https://reactome.org/PathwayBrowser/#/R-HSA-1222353 Protonation of superoxide TAS Homo sapiens 25941 R-BTA-3697882 https://reactome.org/PathwayBrowser/#/R-BTA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Bos taurus 25941 R-BTA-3697894 https://reactome.org/PathwayBrowser/#/R-BTA-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Bos taurus 25941 R-BTA-9854368 https://reactome.org/PathwayBrowser/#/R-BTA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Bos taurus 25941 R-CEL-9854368 https://reactome.org/PathwayBrowser/#/R-CEL-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Caenorhabditis elegans 25941 R-CFA-3697882 https://reactome.org/PathwayBrowser/#/R-CFA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Canis familiaris 25941 R-CFA-9854368 https://reactome.org/PathwayBrowser/#/R-CFA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Canis familiaris 25941 R-DDI-3697882 https://reactome.org/PathwayBrowser/#/R-DDI-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Dictyostelium discoideum 25941 R-DDI-3697894 https://reactome.org/PathwayBrowser/#/R-DDI-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Dictyostelium discoideum 25941 R-DDI-9854368 https://reactome.org/PathwayBrowser/#/R-DDI-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Dictyostelium discoideum 25941 R-DME-3697882 https://reactome.org/PathwayBrowser/#/R-DME-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Drosophila melanogaster 25941 R-DME-3697894 https://reactome.org/PathwayBrowser/#/R-DME-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Drosophila melanogaster 25941 R-DME-9854368 https://reactome.org/PathwayBrowser/#/R-DME-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Drosophila melanogaster 25941 R-DRE-3697882 https://reactome.org/PathwayBrowser/#/R-DRE-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Danio rerio 25941 R-DRE-3697894 https://reactome.org/PathwayBrowser/#/R-DRE-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Danio rerio 25941 R-DRE-9854368 https://reactome.org/PathwayBrowser/#/R-DRE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Danio rerio 25941 R-GGA-9854368 https://reactome.org/PathwayBrowser/#/R-GGA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Gallus gallus 25941 R-HSA-1222407 https://reactome.org/PathwayBrowser/#/R-HSA-1222407 Superoxide and nitric oxide react to peroxynitrite TAS Homo sapiens 25941 R-HSA-1222411 https://reactome.org/PathwayBrowser/#/R-HSA-1222411 Peroxynitrite oxidizes Peptide-Methionine residues TAS Homo sapiens 25941 R-HSA-1222431 https://reactome.org/PathwayBrowser/#/R-HSA-1222431 Peroxynitrite is reduced to nitrite by AhpC TAS Homo sapiens 25941 R-HSA-1222755 https://reactome.org/PathwayBrowser/#/R-HSA-1222755 Peroxynitrite is reduced to nitrite by Tpx TAS Homo sapiens 25941 R-HSA-1470073 https://reactome.org/PathwayBrowser/#/R-HSA-1470073 Peroxynitrite enters the bacterium TAS Homo sapiens 25941 R-HSA-1497866 https://reactome.org/PathwayBrowser/#/R-HSA-1497866 Peroxynitrite can oxidise BH4 to the BH3 radical TAS Homo sapiens 25941 R-HSA-1497878 https://reactome.org/PathwayBrowser/#/R-HSA-1497878 Superoxide reacts rapidly with NO to form peroxynitrite (ONOO-) TAS Homo sapiens 25941 R-HSA-1500804 https://reactome.org/PathwayBrowser/#/R-HSA-1500804 Peroxynitrite is reduced by AhpE TAS Homo sapiens 25941 R-HSA-3697855 https://reactome.org/PathwayBrowser/#/R-HSA-3697855 Superoxide and nitric oxide react to form peroxynitrite in mitochondria TAS Homo sapiens 25941 R-HSA-3697882 https://reactome.org/PathwayBrowser/#/R-HSA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN TAS Homo sapiens 25941 R-HSA-3697894 https://reactome.org/PathwayBrowser/#/R-HSA-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 TAS Homo sapiens 25941 R-HSA-8942052 https://reactome.org/PathwayBrowser/#/R-HSA-8942052 Superoxide and nitric oxide react to peroxynitrite in the phagosome TAS Homo sapiens 25941 R-HSA-8942075 https://reactome.org/PathwayBrowser/#/R-HSA-8942075 Peroxynitrite and carbon dioxide react to nitrosoperoxycarbonate TAS Homo sapiens 25941 R-HSA-8948180 https://reactome.org/PathwayBrowser/#/R-HSA-8948180 Peroxynitrite oxidizes Cys residues TAS Homo sapiens 25941 R-HSA-9854368 https://reactome.org/PathwayBrowser/#/R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S TAS Homo sapiens 25941 R-MMU-3697882 https://reactome.org/PathwayBrowser/#/R-MMU-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Mus musculus 25941 R-MMU-3697894 https://reactome.org/PathwayBrowser/#/R-MMU-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Mus musculus 25941 R-MMU-9854368 https://reactome.org/PathwayBrowser/#/R-MMU-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Mus musculus 25941 R-PFA-3697882 https://reactome.org/PathwayBrowser/#/R-PFA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Plasmodium falciparum 25941 R-RNO-3697882 https://reactome.org/PathwayBrowser/#/R-RNO-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Rattus norvegicus 25941 R-RNO-3697894 https://reactome.org/PathwayBrowser/#/R-RNO-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Rattus norvegicus 25941 R-RNO-9854368 https://reactome.org/PathwayBrowser/#/R-RNO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Rattus norvegicus 25941 R-SCE-3697882 https://reactome.org/PathwayBrowser/#/R-SCE-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Saccharomyces cerevisiae 25941 R-SCE-9854368 https://reactome.org/PathwayBrowser/#/R-SCE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Saccharomyces cerevisiae 25941 R-SPO-3697882 https://reactome.org/PathwayBrowser/#/R-SPO-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Schizosaccharomyces pombe 25941 R-SPO-9854368 https://reactome.org/PathwayBrowser/#/R-SPO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Schizosaccharomyces pombe 25941 R-SSC-3697882 https://reactome.org/PathwayBrowser/#/R-SSC-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Sus scrofa 25941 R-SSC-3697894 https://reactome.org/PathwayBrowser/#/R-SSC-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Sus scrofa 25941 R-SSC-9854368 https://reactome.org/PathwayBrowser/#/R-SSC-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Sus scrofa 25941 R-XTR-3697894 https://reactome.org/PathwayBrowser/#/R-XTR-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Xenopus tropicalis 25941 R-XTR-9854368 https://reactome.org/PathwayBrowser/#/R-XTR-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Xenopus tropicalis 26034 R-BTA-5672012 https://reactome.org/PathwayBrowser/#/R-BTA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Bos taurus 26034 R-BTA-5679206 https://reactome.org/PathwayBrowser/#/R-BTA-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Bos taurus 26034 R-BTA-6809777 https://reactome.org/PathwayBrowser/#/R-BTA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Bos taurus 26034 R-CEL-5672012 https://reactome.org/PathwayBrowser/#/R-CEL-5672012 Beclin-1 complex phosphorylates PtdIns IEA Caenorhabditis elegans 26034 R-CEL-6809777 https://reactome.org/PathwayBrowser/#/R-CEL-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Caenorhabditis elegans 26034 R-CFA-5672012 https://reactome.org/PathwayBrowser/#/R-CFA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Canis familiaris 26034 R-CFA-5679206 https://reactome.org/PathwayBrowser/#/R-CFA-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Canis familiaris 26034 R-CFA-6809777 https://reactome.org/PathwayBrowser/#/R-CFA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Canis familiaris 26034 R-DDI-5672012 https://reactome.org/PathwayBrowser/#/R-DDI-5672012 Beclin-1 complex phosphorylates PtdIns IEA Dictyostelium discoideum 26034 R-DDI-5679206 https://reactome.org/PathwayBrowser/#/R-DDI-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Dictyostelium discoideum 26034 R-DDI-6809777 https://reactome.org/PathwayBrowser/#/R-DDI-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Dictyostelium discoideum 26034 R-DME-5672012 https://reactome.org/PathwayBrowser/#/R-DME-5672012 Beclin-1 complex phosphorylates PtdIns IEA Drosophila melanogaster 26034 R-DME-5679206 https://reactome.org/PathwayBrowser/#/R-DME-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Drosophila melanogaster 26034 R-DME-6809777 https://reactome.org/PathwayBrowser/#/R-DME-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Drosophila melanogaster 26034 R-GGA-5672012 https://reactome.org/PathwayBrowser/#/R-GGA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Gallus gallus 26034 R-GGA-5679206 https://reactome.org/PathwayBrowser/#/R-GGA-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Gallus gallus 26034 R-GGA-6809777 https://reactome.org/PathwayBrowser/#/R-GGA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Gallus gallus 26034 R-HSA-5672012 https://reactome.org/PathwayBrowser/#/R-HSA-5672012 Beclin-1 complex phosphorylates PtdIns TAS Homo sapiens 26034 R-HSA-5679206 https://reactome.org/PathwayBrowser/#/R-HSA-5679206 MTMR14, MTMR3 dephosphorylate PI3P TAS Homo sapiens 26034 R-HSA-6809777 https://reactome.org/PathwayBrowser/#/R-HSA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 TAS Homo sapiens 26034 R-HSA-9636457 https://reactome.org/PathwayBrowser/#/R-HSA-9636457 SapM dephosphorylates PI3P TAS Homo sapiens 26034 R-MMU-5672012 https://reactome.org/PathwayBrowser/#/R-MMU-5672012 Beclin-1 complex phosphorylates PtdIns IEA Mus musculus 26034 R-MMU-5679206 https://reactome.org/PathwayBrowser/#/R-MMU-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Mus musculus 26034 R-MMU-6809777 https://reactome.org/PathwayBrowser/#/R-MMU-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Mus musculus 26034 R-RNO-5672012 https://reactome.org/PathwayBrowser/#/R-RNO-5672012 Beclin-1 complex phosphorylates PtdIns IEA Rattus norvegicus 26034 R-RNO-5679206 https://reactome.org/PathwayBrowser/#/R-RNO-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Rattus norvegicus 26034 R-RNO-6809777 https://reactome.org/PathwayBrowser/#/R-RNO-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Rattus norvegicus 26034 R-SCE-5672012 https://reactome.org/PathwayBrowser/#/R-SCE-5672012 Beclin-1 complex phosphorylates PtdIns IEA Saccharomyces cerevisiae 26034 R-SCE-5679206 https://reactome.org/PathwayBrowser/#/R-SCE-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Saccharomyces cerevisiae 26034 R-SCE-6809777 https://reactome.org/PathwayBrowser/#/R-SCE-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Saccharomyces cerevisiae 26034 R-SPO-5672012 https://reactome.org/PathwayBrowser/#/R-SPO-5672012 Beclin-1 complex phosphorylates PtdIns IEA Schizosaccharomyces pombe 26034 R-SPO-5679206 https://reactome.org/PathwayBrowser/#/R-SPO-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Schizosaccharomyces pombe 26034 R-SPO-6809777 https://reactome.org/PathwayBrowser/#/R-SPO-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Schizosaccharomyces pombe 26034 R-SSC-5672012 https://reactome.org/PathwayBrowser/#/R-SSC-5672012 Beclin-1 complex phosphorylates PtdIns IEA Sus scrofa 26034 R-SSC-5679206 https://reactome.org/PathwayBrowser/#/R-SSC-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Sus scrofa 26034 R-SSC-6809777 https://reactome.org/PathwayBrowser/#/R-SSC-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Sus scrofa 26034 R-XTR-5672012 https://reactome.org/PathwayBrowser/#/R-XTR-5672012 Beclin-1 complex phosphorylates PtdIns IEA Xenopus tropicalis 26034 R-XTR-5679206 https://reactome.org/PathwayBrowser/#/R-XTR-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Xenopus tropicalis 26125 R-BTA-265783 https://reactome.org/PathwayBrowser/#/R-BTA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Bos taurus 26125 R-CEL-265783 https://reactome.org/PathwayBrowser/#/R-CEL-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Caenorhabditis elegans 26125 R-CFA-265783 https://reactome.org/PathwayBrowser/#/R-CFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Canis familiaris 26125 R-DDI-265783 https://reactome.org/PathwayBrowser/#/R-DDI-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Dictyostelium discoideum 26125 R-DME-265783 https://reactome.org/PathwayBrowser/#/R-DME-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Drosophila melanogaster 26125 R-GGA-265783 https://reactome.org/PathwayBrowser/#/R-GGA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Gallus gallus 26125 R-HSA-265545 https://reactome.org/PathwayBrowser/#/R-HSA-265545 NPC1L1-mediated phytosterol uptake IEA Homo sapiens 26125 R-HSA-265783 https://reactome.org/PathwayBrowser/#/R-HSA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region TAS Homo sapiens 26125 R-HSA-5679101 https://reactome.org/PathwayBrowser/#/R-HSA-5679101 Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 26125 R-HSA-5679145 https://reactome.org/PathwayBrowser/#/R-HSA-5679145 Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 26125 R-MMU-265783 https://reactome.org/PathwayBrowser/#/R-MMU-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Mus musculus 26125 R-PFA-265783 https://reactome.org/PathwayBrowser/#/R-PFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Plasmodium falciparum 26125 R-RNO-265783 https://reactome.org/PathwayBrowser/#/R-RNO-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Rattus norvegicus 26125 R-SCE-265783 https://reactome.org/PathwayBrowser/#/R-SCE-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Saccharomyces cerevisiae 26125 R-SSC-265783 https://reactome.org/PathwayBrowser/#/R-SSC-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Sus scrofa 2622 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 2622 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2622 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2622 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2622 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 2622 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 2622 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2622 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2622 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2622 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 2622 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 2622 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2622 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 2622 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 2622 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2622 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 2622 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2622 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 2622 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 2622 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2622 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2622 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2622 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 2622 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 2622 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 2622 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 2622 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2622 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2622 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2622 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 2622 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 2622 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2622 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 2622 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 2622 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2622 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2622 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2622 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 2622 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 2622 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2622 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 2622 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 26355 R-BTA-140355 https://reactome.org/PathwayBrowser/#/R-BTA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Bos taurus 26355 R-BTA-140359 https://reactome.org/PathwayBrowser/#/R-BTA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Bos taurus 26355 R-BTA-2161951 https://reactome.org/PathwayBrowser/#/R-BTA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Bos taurus 26355 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 26355 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 26355 R-BTA-2309787 https://reactome.org/PathwayBrowser/#/R-BTA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Bos taurus 26355 R-BTA-2314678 https://reactome.org/PathwayBrowser/#/R-BTA-2314678 ASA- acetylates PTGS1 IEA Bos taurus 26355 R-BTA-2314686 https://reactome.org/PathwayBrowser/#/R-BTA-2314686 ASA- acetylates PTGS2 IEA Bos taurus 26355 R-BTA-70994 https://reactome.org/PathwayBrowser/#/R-BTA-70994 SDH complex dehydrogenates succinate IEA Bos taurus 26355 R-BTA-9018880 https://reactome.org/PathwayBrowser/#/R-BTA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Bos taurus 26355 R-BTA-9020261 https://reactome.org/PathwayBrowser/#/R-BTA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Bos taurus 26355 R-BTA-9026408 https://reactome.org/PathwayBrowser/#/R-BTA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Bos taurus 26355 R-BTA-9027532 https://reactome.org/PathwayBrowser/#/R-BTA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Bos taurus 26355 R-BTA-9027607 https://reactome.org/PathwayBrowser/#/R-BTA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Bos taurus 26355 R-BTA-9027627 https://reactome.org/PathwayBrowser/#/R-BTA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Bos taurus 26355 R-BTA-9028255 https://reactome.org/PathwayBrowser/#/R-BTA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Bos taurus 26355 R-BTA-917811 https://reactome.org/PathwayBrowser/#/R-BTA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Bos taurus 26355 R-BTA-9677320 https://reactome.org/PathwayBrowser/#/R-BTA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Bos taurus 26355 R-BTA-9855252 https://reactome.org/PathwayBrowser/#/R-BTA-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Bos taurus 26355 R-CEL-70994 https://reactome.org/PathwayBrowser/#/R-CEL-70994 SDH complex dehydrogenates succinate IEA Caenorhabditis elegans 26355 R-CFA-140355 https://reactome.org/PathwayBrowser/#/R-CFA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Canis familiaris 26355 R-CFA-140359 https://reactome.org/PathwayBrowser/#/R-CFA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Canis familiaris 26355 R-CFA-2161951 https://reactome.org/PathwayBrowser/#/R-CFA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Canis familiaris 26355 R-CFA-2168881 https://reactome.org/PathwayBrowser/#/R-CFA-2168881 Truncated Alpha-1-Microglobulin binds heme IEA Canis familiaris 26355 R-CFA-2168888 https://reactome.org/PathwayBrowser/#/R-CFA-2168888 Alpha1-Microglobulin binds heme IEA Canis familiaris 26355 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 26355 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 26355 R-CFA-2309787 https://reactome.org/PathwayBrowser/#/R-CFA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Canis familiaris 26355 R-CFA-2314678 https://reactome.org/PathwayBrowser/#/R-CFA-2314678 ASA- acetylates PTGS1 IEA Canis familiaris 26355 R-CFA-2314686 https://reactome.org/PathwayBrowser/#/R-CFA-2314686 ASA- acetylates PTGS2 IEA Canis familiaris 26355 R-CFA-70994 https://reactome.org/PathwayBrowser/#/R-CFA-70994 SDH complex dehydrogenates succinate IEA Canis familiaris 26355 R-CFA-9018880 https://reactome.org/PathwayBrowser/#/R-CFA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Canis familiaris 26355 R-CFA-9020261 https://reactome.org/PathwayBrowser/#/R-CFA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Canis familiaris 26355 R-CFA-9026408 https://reactome.org/PathwayBrowser/#/R-CFA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Canis familiaris 26355 R-CFA-9027532 https://reactome.org/PathwayBrowser/#/R-CFA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Canis familiaris 26355 R-CFA-9027607 https://reactome.org/PathwayBrowser/#/R-CFA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Canis familiaris 26355 R-CFA-9027627 https://reactome.org/PathwayBrowser/#/R-CFA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Canis familiaris 26355 R-CFA-9028255 https://reactome.org/PathwayBrowser/#/R-CFA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Canis familiaris 26355 R-CFA-917811 https://reactome.org/PathwayBrowser/#/R-CFA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Canis familiaris 26355 R-CFA-9677320 https://reactome.org/PathwayBrowser/#/R-CFA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Canis familiaris 26355 R-DDI-70994 https://reactome.org/PathwayBrowser/#/R-DDI-70994 SDH complex dehydrogenates succinate IEA Dictyostelium discoideum 26355 R-DME-70994 https://reactome.org/PathwayBrowser/#/R-DME-70994 SDH complex dehydrogenates succinate IEA Drosophila melanogaster 26355 R-DRE-140355 https://reactome.org/PathwayBrowser/#/R-DRE-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Danio rerio 26355 R-DRE-140359 https://reactome.org/PathwayBrowser/#/R-DRE-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Danio rerio 26355 R-DRE-2161951 https://reactome.org/PathwayBrowser/#/R-DRE-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Danio rerio 26355 R-DRE-2168881 https://reactome.org/PathwayBrowser/#/R-DRE-2168881 Truncated Alpha-1-Microglobulin binds heme IEA Danio rerio 26355 R-DRE-2168888 https://reactome.org/PathwayBrowser/#/R-DRE-2168888 Alpha1-Microglobulin binds heme IEA Danio rerio 26355 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 26355 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 26355 R-DRE-2309787 https://reactome.org/PathwayBrowser/#/R-DRE-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Danio rerio 26355 R-DRE-2314678 https://reactome.org/PathwayBrowser/#/R-DRE-2314678 ASA- acetylates PTGS1 IEA Danio rerio 26355 R-DRE-2314686 https://reactome.org/PathwayBrowser/#/R-DRE-2314686 ASA- acetylates PTGS2 IEA Danio rerio 26355 R-DRE-70994 https://reactome.org/PathwayBrowser/#/R-DRE-70994 SDH complex dehydrogenates succinate IEA Danio rerio 26355 R-DRE-9018880 https://reactome.org/PathwayBrowser/#/R-DRE-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Danio rerio 26355 R-DRE-9020261 https://reactome.org/PathwayBrowser/#/R-DRE-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Danio rerio 26355 R-DRE-9026408 https://reactome.org/PathwayBrowser/#/R-DRE-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Danio rerio 26355 R-DRE-9027532 https://reactome.org/PathwayBrowser/#/R-DRE-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Danio rerio 26355 R-DRE-9027607 https://reactome.org/PathwayBrowser/#/R-DRE-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Danio rerio 26355 R-DRE-9027627 https://reactome.org/PathwayBrowser/#/R-DRE-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Danio rerio 26355 R-DRE-9028255 https://reactome.org/PathwayBrowser/#/R-DRE-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Danio rerio 26355 R-DRE-9677320 https://reactome.org/PathwayBrowser/#/R-DRE-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Danio rerio 26355 R-GGA-140355 https://reactome.org/PathwayBrowser/#/R-GGA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Gallus gallus 26355 R-GGA-140359 https://reactome.org/PathwayBrowser/#/R-GGA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Gallus gallus 26355 R-GGA-2161951 https://reactome.org/PathwayBrowser/#/R-GGA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Gallus gallus 26355 R-GGA-2168881 https://reactome.org/PathwayBrowser/#/R-GGA-2168881 Truncated Alpha-1-Microglobulin binds heme IEA Gallus gallus 26355 R-GGA-2168888 https://reactome.org/PathwayBrowser/#/R-GGA-2168888 Alpha1-Microglobulin binds heme IEA Gallus gallus 26355 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 26355 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 26355 R-GGA-2309787 https://reactome.org/PathwayBrowser/#/R-GGA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Gallus gallus 26355 R-GGA-2314678 https://reactome.org/PathwayBrowser/#/R-GGA-2314678 ASA- acetylates PTGS1 IEA Gallus gallus 26355 R-GGA-2314686 https://reactome.org/PathwayBrowser/#/R-GGA-2314686 ASA- acetylates PTGS2 IEA Gallus gallus 26355 R-GGA-70994 https://reactome.org/PathwayBrowser/#/R-GGA-70994 SDH complex dehydrogenates succinate IEA Gallus gallus 26355 R-GGA-9018880 https://reactome.org/PathwayBrowser/#/R-GGA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Gallus gallus 26355 R-GGA-9020261 https://reactome.org/PathwayBrowser/#/R-GGA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Gallus gallus 26355 R-GGA-9026408 https://reactome.org/PathwayBrowser/#/R-GGA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Gallus gallus 26355 R-GGA-9027532 https://reactome.org/PathwayBrowser/#/R-GGA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Gallus gallus 26355 R-GGA-9027607 https://reactome.org/PathwayBrowser/#/R-GGA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Gallus gallus 26355 R-GGA-9027627 https://reactome.org/PathwayBrowser/#/R-GGA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Gallus gallus 26355 R-GGA-9028255 https://reactome.org/PathwayBrowser/#/R-GGA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Gallus gallus 26355 R-GGA-917811 https://reactome.org/PathwayBrowser/#/R-GGA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Gallus gallus 26355 R-GGA-9677320 https://reactome.org/PathwayBrowser/#/R-GGA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Gallus gallus 26355 R-HSA-140355 https://reactome.org/PathwayBrowser/#/R-HSA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 TAS Homo sapiens 26355 R-HSA-140359 https://reactome.org/PathwayBrowser/#/R-HSA-140359 PGG2 is reduced to PGH2 by PTGS1 TAS Homo sapiens 26355 R-HSA-163213 https://reactome.org/PathwayBrowser/#/R-HSA-163213 Transfer of electrons through the succinate dehydrogenase complex IEA Homo sapiens 26355 R-HSA-2161951 https://reactome.org/PathwayBrowser/#/R-HSA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 TAS Homo sapiens 26355 R-HSA-2168881 https://reactome.org/PathwayBrowser/#/R-HSA-2168881 Truncated Alpha-1-Microglobulin binds heme TAS Homo sapiens 26355 R-HSA-2168888 https://reactome.org/PathwayBrowser/#/R-HSA-2168888 Alpha1-Microglobulin binds heme TAS Homo sapiens 26355 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 26355 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 26355 R-HSA-2309787 https://reactome.org/PathwayBrowser/#/R-HSA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 TAS Homo sapiens 26355 R-HSA-2314678 https://reactome.org/PathwayBrowser/#/R-HSA-2314678 ASA- acetylates PTGS1 TAS Homo sapiens 26355 R-HSA-2314686 https://reactome.org/PathwayBrowser/#/R-HSA-2314686 ASA- acetylates PTGS2 TAS Homo sapiens 26355 R-HSA-70994 https://reactome.org/PathwayBrowser/#/R-HSA-70994 SDH complex dehydrogenates succinate TAS Homo sapiens 26355 R-HSA-9018880 https://reactome.org/PathwayBrowser/#/R-HSA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE TAS Homo sapiens 26355 R-HSA-9020261 https://reactome.org/PathwayBrowser/#/R-HSA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA TAS Homo sapiens 26355 R-HSA-9026408 https://reactome.org/PathwayBrowser/#/R-HSA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 TAS Homo sapiens 26355 R-HSA-9027532 https://reactome.org/PathwayBrowser/#/R-HSA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA TAS Homo sapiens 26355 R-HSA-9027607 https://reactome.org/PathwayBrowser/#/R-HSA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 TAS Homo sapiens 26355 R-HSA-9027627 https://reactome.org/PathwayBrowser/#/R-HSA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) TAS Homo sapiens 26355 R-HSA-9028255 https://reactome.org/PathwayBrowser/#/R-HSA-9028255 PTGS2 dimer oxidises EPA to PGH3 TAS Homo sapiens 26355 R-HSA-917811 https://reactome.org/PathwayBrowser/#/R-HSA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ TAS Homo sapiens 26355 R-HSA-9677320 https://reactome.org/PathwayBrowser/#/R-HSA-9677320 PTGS1 dimer binds PTGS1 Inhibitors TAS Homo sapiens 26355 R-HSA-9855252 https://reactome.org/PathwayBrowser/#/R-HSA-9855252 SDHA:SDHB binds to SDHC:SDHD TAS Homo sapiens 26355 R-MMU-140355 https://reactome.org/PathwayBrowser/#/R-MMU-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Mus musculus 26355 R-MMU-140359 https://reactome.org/PathwayBrowser/#/R-MMU-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Mus musculus 26355 R-MMU-2161951 https://reactome.org/PathwayBrowser/#/R-MMU-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Mus musculus 26355 R-MMU-2168881 https://reactome.org/PathwayBrowser/#/R-MMU-2168881 Truncated Alpha-1-Microglobulin binds heme IEA Mus musculus 26355 R-MMU-2168888 https://reactome.org/PathwayBrowser/#/R-MMU-2168888 Alpha1-Microglobulin binds heme IEA Mus musculus 26355 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 26355 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 26355 R-MMU-2309787 https://reactome.org/PathwayBrowser/#/R-MMU-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Mus musculus 26355 R-MMU-2314678 https://reactome.org/PathwayBrowser/#/R-MMU-2314678 ASA- acetylates PTGS1 IEA Mus musculus 26355 R-MMU-2314686 https://reactome.org/PathwayBrowser/#/R-MMU-2314686 ASA- acetylates PTGS2 IEA Mus musculus 26355 R-MMU-70994 https://reactome.org/PathwayBrowser/#/R-MMU-70994 SDH complex dehydrogenates succinate IEA Mus musculus 26355 R-MMU-9018880 https://reactome.org/PathwayBrowser/#/R-MMU-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Mus musculus 26355 R-MMU-9020261 https://reactome.org/PathwayBrowser/#/R-MMU-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Mus musculus 26355 R-MMU-9026408 https://reactome.org/PathwayBrowser/#/R-MMU-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Mus musculus 26355 R-MMU-9027532 https://reactome.org/PathwayBrowser/#/R-MMU-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Mus musculus 26355 R-MMU-9027607 https://reactome.org/PathwayBrowser/#/R-MMU-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Mus musculus 26355 R-MMU-9027627 https://reactome.org/PathwayBrowser/#/R-MMU-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Mus musculus 26355 R-MMU-9028255 https://reactome.org/PathwayBrowser/#/R-MMU-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Mus musculus 26355 R-MMU-917811 https://reactome.org/PathwayBrowser/#/R-MMU-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Mus musculus 26355 R-MMU-9677320 https://reactome.org/PathwayBrowser/#/R-MMU-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Mus musculus 26355 R-MMU-9855252 https://reactome.org/PathwayBrowser/#/R-MMU-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Mus musculus 26355 R-RNO-140355 https://reactome.org/PathwayBrowser/#/R-RNO-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Rattus norvegicus 26355 R-RNO-140359 https://reactome.org/PathwayBrowser/#/R-RNO-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Rattus norvegicus 26355 R-RNO-2161951 https://reactome.org/PathwayBrowser/#/R-RNO-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Rattus norvegicus 26355 R-RNO-2168881 https://reactome.org/PathwayBrowser/#/R-RNO-2168881 Truncated Alpha-1-Microglobulin binds heme IEA Rattus norvegicus 26355 R-RNO-2168888 https://reactome.org/PathwayBrowser/#/R-RNO-2168888 Alpha1-Microglobulin binds heme IEA Rattus norvegicus 26355 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 26355 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 26355 R-RNO-2309787 https://reactome.org/PathwayBrowser/#/R-RNO-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Rattus norvegicus 26355 R-RNO-2314678 https://reactome.org/PathwayBrowser/#/R-RNO-2314678 ASA- acetylates PTGS1 IEA Rattus norvegicus 26355 R-RNO-2314686 https://reactome.org/PathwayBrowser/#/R-RNO-2314686 ASA- acetylates PTGS2 IEA Rattus norvegicus 26355 R-RNO-70994 https://reactome.org/PathwayBrowser/#/R-RNO-70994 SDH complex dehydrogenates succinate IEA Rattus norvegicus 26355 R-RNO-9018880 https://reactome.org/PathwayBrowser/#/R-RNO-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Rattus norvegicus 26355 R-RNO-9020261 https://reactome.org/PathwayBrowser/#/R-RNO-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Rattus norvegicus 26355 R-RNO-9026408 https://reactome.org/PathwayBrowser/#/R-RNO-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Rattus norvegicus 26355 R-RNO-9027532 https://reactome.org/PathwayBrowser/#/R-RNO-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Rattus norvegicus 26355 R-RNO-9027607 https://reactome.org/PathwayBrowser/#/R-RNO-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Rattus norvegicus 26355 R-RNO-9027627 https://reactome.org/PathwayBrowser/#/R-RNO-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Rattus norvegicus 26355 R-RNO-9028255 https://reactome.org/PathwayBrowser/#/R-RNO-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Rattus norvegicus 26355 R-RNO-917811 https://reactome.org/PathwayBrowser/#/R-RNO-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Rattus norvegicus 26355 R-RNO-9677320 https://reactome.org/PathwayBrowser/#/R-RNO-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Rattus norvegicus 26355 R-SCE-70994 https://reactome.org/PathwayBrowser/#/R-SCE-70994 SDH complex dehydrogenates succinate IEA Saccharomyces cerevisiae 26355 R-SPO-70994 https://reactome.org/PathwayBrowser/#/R-SPO-70994 SDH complex dehydrogenates succinate IEA Schizosaccharomyces pombe 26355 R-SSC-140355 https://reactome.org/PathwayBrowser/#/R-SSC-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Sus scrofa 26355 R-SSC-140359 https://reactome.org/PathwayBrowser/#/R-SSC-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Sus scrofa 26355 R-SSC-2161951 https://reactome.org/PathwayBrowser/#/R-SSC-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Sus scrofa 26355 R-SSC-2168881 https://reactome.org/PathwayBrowser/#/R-SSC-2168881 Truncated Alpha-1-Microglobulin binds heme IEA Sus scrofa 26355 R-SSC-2168888 https://reactome.org/PathwayBrowser/#/R-SSC-2168888 Alpha1-Microglobulin binds heme IEA Sus scrofa 26355 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 26355 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 26355 R-SSC-2309787 https://reactome.org/PathwayBrowser/#/R-SSC-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Sus scrofa 26355 R-SSC-2314678 https://reactome.org/PathwayBrowser/#/R-SSC-2314678 ASA- acetylates PTGS1 IEA Sus scrofa 26355 R-SSC-2314686 https://reactome.org/PathwayBrowser/#/R-SSC-2314686 ASA- acetylates PTGS2 IEA Sus scrofa 26355 R-SSC-70994 https://reactome.org/PathwayBrowser/#/R-SSC-70994 SDH complex dehydrogenates succinate IEA Sus scrofa 26355 R-SSC-9018880 https://reactome.org/PathwayBrowser/#/R-SSC-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Sus scrofa 26355 R-SSC-9020261 https://reactome.org/PathwayBrowser/#/R-SSC-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Sus scrofa 26355 R-SSC-9026408 https://reactome.org/PathwayBrowser/#/R-SSC-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Sus scrofa 26355 R-SSC-9027532 https://reactome.org/PathwayBrowser/#/R-SSC-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Sus scrofa 26355 R-SSC-9027607 https://reactome.org/PathwayBrowser/#/R-SSC-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Sus scrofa 26355 R-SSC-9027627 https://reactome.org/PathwayBrowser/#/R-SSC-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Sus scrofa 26355 R-SSC-9028255 https://reactome.org/PathwayBrowser/#/R-SSC-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Sus scrofa 26355 R-SSC-917811 https://reactome.org/PathwayBrowser/#/R-SSC-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Sus scrofa 26355 R-SSC-9677320 https://reactome.org/PathwayBrowser/#/R-SSC-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Sus scrofa 26355 R-SSC-9855252 https://reactome.org/PathwayBrowser/#/R-SSC-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Sus scrofa 26355 R-XTR-140355 https://reactome.org/PathwayBrowser/#/R-XTR-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Xenopus tropicalis 26355 R-XTR-140359 https://reactome.org/PathwayBrowser/#/R-XTR-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Xenopus tropicalis 26355 R-XTR-2161951 https://reactome.org/PathwayBrowser/#/R-XTR-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Xenopus tropicalis 26355 R-XTR-2168881 https://reactome.org/PathwayBrowser/#/R-XTR-2168881 Truncated Alpha-1-Microglobulin binds heme IEA Xenopus tropicalis 26355 R-XTR-2168888 https://reactome.org/PathwayBrowser/#/R-XTR-2168888 Alpha1-Microglobulin binds heme IEA Xenopus tropicalis 26355 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 26355 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 26355 R-XTR-2309787 https://reactome.org/PathwayBrowser/#/R-XTR-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Xenopus tropicalis 26355 R-XTR-2314678 https://reactome.org/PathwayBrowser/#/R-XTR-2314678 ASA- acetylates PTGS1 IEA Xenopus tropicalis 26355 R-XTR-2314686 https://reactome.org/PathwayBrowser/#/R-XTR-2314686 ASA- acetylates PTGS2 IEA Xenopus tropicalis 26355 R-XTR-70994 https://reactome.org/PathwayBrowser/#/R-XTR-70994 SDH complex dehydrogenates succinate IEA Xenopus tropicalis 26355 R-XTR-9018880 https://reactome.org/PathwayBrowser/#/R-XTR-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Xenopus tropicalis 26355 R-XTR-9020261 https://reactome.org/PathwayBrowser/#/R-XTR-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Xenopus tropicalis 26355 R-XTR-9026408 https://reactome.org/PathwayBrowser/#/R-XTR-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Xenopus tropicalis 26355 R-XTR-9027532 https://reactome.org/PathwayBrowser/#/R-XTR-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Xenopus tropicalis 26355 R-XTR-9027607 https://reactome.org/PathwayBrowser/#/R-XTR-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Xenopus tropicalis 26355 R-XTR-9027627 https://reactome.org/PathwayBrowser/#/R-XTR-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Xenopus tropicalis 26355 R-XTR-9028255 https://reactome.org/PathwayBrowser/#/R-XTR-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Xenopus tropicalis 26355 R-XTR-917811 https://reactome.org/PathwayBrowser/#/R-XTR-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Xenopus tropicalis 26355 R-XTR-9677320 https://reactome.org/PathwayBrowser/#/R-XTR-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Xenopus tropicalis 26355 R-XTR-9855252 https://reactome.org/PathwayBrowser/#/R-XTR-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Xenopus tropicalis 2651 R-BTA-156808 https://reactome.org/PathwayBrowser/#/R-BTA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Bos taurus 2651 R-BTA-156823 https://reactome.org/PathwayBrowser/#/R-BTA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Bos taurus 2651 R-BTA-157849 https://reactome.org/PathwayBrowser/#/R-BTA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Bos taurus 2651 R-BTA-72621 https://reactome.org/PathwayBrowser/#/R-BTA-72621 Ribosomal scanning IEA Bos taurus 2651 R-BTA-72669 https://reactome.org/PathwayBrowser/#/R-BTA-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Bos taurus 2651 R-BTA-72671 https://reactome.org/PathwayBrowser/#/R-BTA-72671 eIF5B:GTP is hydrolyzed and released IEA Bos taurus 2651 R-BTA-72672 https://reactome.org/PathwayBrowser/#/R-BTA-72672 The 60S subunit joins the translation initiation complex IEA Bos taurus 2651 R-BTA-72691 https://reactome.org/PathwayBrowser/#/R-BTA-72691 Formation of the 43S pre-initiation complex IEA Bos taurus 2651 R-BTA-72697 https://reactome.org/PathwayBrowser/#/R-BTA-72697 Start codon recognition IEA Bos taurus 2651 R-CEL-156808 https://reactome.org/PathwayBrowser/#/R-CEL-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Caenorhabditis elegans 2651 R-CEL-156823 https://reactome.org/PathwayBrowser/#/R-CEL-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Caenorhabditis elegans 2651 R-CEL-157849 https://reactome.org/PathwayBrowser/#/R-CEL-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Caenorhabditis elegans 2651 R-CEL-72621 https://reactome.org/PathwayBrowser/#/R-CEL-72621 Ribosomal scanning IEA Caenorhabditis elegans 2651 R-CEL-72669 https://reactome.org/PathwayBrowser/#/R-CEL-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Caenorhabditis elegans 2651 R-CEL-72671 https://reactome.org/PathwayBrowser/#/R-CEL-72671 eIF5B:GTP is hydrolyzed and released IEA Caenorhabditis elegans 2651 R-CEL-72672 https://reactome.org/PathwayBrowser/#/R-CEL-72672 The 60S subunit joins the translation initiation complex IEA Caenorhabditis elegans 2651 R-CEL-72691 https://reactome.org/PathwayBrowser/#/R-CEL-72691 Formation of the 43S pre-initiation complex IEA Caenorhabditis elegans 2651 R-CEL-72697 https://reactome.org/PathwayBrowser/#/R-CEL-72697 Start codon recognition IEA Caenorhabditis elegans 2651 R-CFA-156808 https://reactome.org/PathwayBrowser/#/R-CFA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Canis familiaris 2651 R-CFA-156823 https://reactome.org/PathwayBrowser/#/R-CFA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Canis familiaris 2651 R-CFA-157849 https://reactome.org/PathwayBrowser/#/R-CFA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Canis familiaris 2651 R-CFA-72619 https://reactome.org/PathwayBrowser/#/R-CFA-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Canis familiaris 2651 R-CFA-72621 https://reactome.org/PathwayBrowser/#/R-CFA-72621 Ribosomal scanning IEA Canis familiaris 2651 R-CFA-72669 https://reactome.org/PathwayBrowser/#/R-CFA-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Canis familiaris 2651 R-CFA-72671 https://reactome.org/PathwayBrowser/#/R-CFA-72671 eIF5B:GTP is hydrolyzed and released IEA Canis familiaris 2651 R-CFA-72672 https://reactome.org/PathwayBrowser/#/R-CFA-72672 The 60S subunit joins the translation initiation complex IEA Canis familiaris 2651 R-CFA-72691 https://reactome.org/PathwayBrowser/#/R-CFA-72691 Formation of the 43S pre-initiation complex IEA Canis familiaris 2651 R-CFA-72697 https://reactome.org/PathwayBrowser/#/R-CFA-72697 Start codon recognition IEA Canis familiaris 2651 R-DDI-156823 https://reactome.org/PathwayBrowser/#/R-DDI-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Dictyostelium discoideum 2651 R-DDI-72621 https://reactome.org/PathwayBrowser/#/R-DDI-72621 Ribosomal scanning IEA Dictyostelium discoideum 2651 R-DDI-72669 https://reactome.org/PathwayBrowser/#/R-DDI-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Dictyostelium discoideum 2651 R-DDI-72671 https://reactome.org/PathwayBrowser/#/R-DDI-72671 eIF5B:GTP is hydrolyzed and released IEA Dictyostelium discoideum 2651 R-DDI-72672 https://reactome.org/PathwayBrowser/#/R-DDI-72672 The 60S subunit joins the translation initiation complex IEA Dictyostelium discoideum 2651 R-DDI-72691 https://reactome.org/PathwayBrowser/#/R-DDI-72691 Formation of the 43S pre-initiation complex IEA Dictyostelium discoideum 2651 R-DDI-72697 https://reactome.org/PathwayBrowser/#/R-DDI-72697 Start codon recognition IEA Dictyostelium discoideum 2651 R-DME-156823 https://reactome.org/PathwayBrowser/#/R-DME-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Drosophila melanogaster 2651 R-DME-157849 https://reactome.org/PathwayBrowser/#/R-DME-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Drosophila melanogaster 2651 R-DME-72621 https://reactome.org/PathwayBrowser/#/R-DME-72621 Ribosomal scanning IEA Drosophila melanogaster 2651 R-DME-72669 https://reactome.org/PathwayBrowser/#/R-DME-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Drosophila melanogaster 2651 R-DME-72671 https://reactome.org/PathwayBrowser/#/R-DME-72671 eIF5B:GTP is hydrolyzed and released IEA Drosophila melanogaster 2651 R-DME-72672 https://reactome.org/PathwayBrowser/#/R-DME-72672 The 60S subunit joins the translation initiation complex IEA Drosophila melanogaster 2651 R-DME-72691 https://reactome.org/PathwayBrowser/#/R-DME-72691 Formation of the 43S pre-initiation complex IEA Drosophila melanogaster 2651 R-DME-72697 https://reactome.org/PathwayBrowser/#/R-DME-72697 Start codon recognition IEA Drosophila melanogaster 2651 R-DRE-156823 https://reactome.org/PathwayBrowser/#/R-DRE-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Danio rerio 2651 R-DRE-72621 https://reactome.org/PathwayBrowser/#/R-DRE-72621 Ribosomal scanning IEA Danio rerio 2651 R-DRE-72669 https://reactome.org/PathwayBrowser/#/R-DRE-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Danio rerio 2651 R-DRE-72691 https://reactome.org/PathwayBrowser/#/R-DRE-72691 Formation of the 43S pre-initiation complex IEA Danio rerio 2651 R-DRE-72697 https://reactome.org/PathwayBrowser/#/R-DRE-72697 Start codon recognition IEA Danio rerio 2651 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 2651 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus 2651 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus 2651 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus 2651 R-GGA-72669 https://reactome.org/PathwayBrowser/#/R-GGA-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Gallus gallus 2651 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus 2651 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus 2651 R-GGA-72691 https://reactome.org/PathwayBrowser/#/R-GGA-72691 Formation of the 43S pre-initiation complex IEA Gallus gallus 2651 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus 2651 R-HSA-156808 https://reactome.org/PathwayBrowser/#/R-HSA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation TAS Homo sapiens 2651 R-HSA-156823 https://reactome.org/PathwayBrowser/#/R-HSA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA TAS Homo sapiens 2651 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 2651 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 2651 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 2651 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 2651 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 2651 R-HSA-157849 https://reactome.org/PathwayBrowser/#/R-HSA-157849 Formation of translation initiation complexes containing mRNA that does not circularize TAS Homo sapiens 2651 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 2651 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 2651 R-HSA-2408529 https://reactome.org/PathwayBrowser/#/R-HSA-2408529 Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome IEA Homo sapiens 2651 R-HSA-5333615 https://reactome.org/PathwayBrowser/#/R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC IEA Homo sapiens 2651 R-HSA-72619 https://reactome.org/PathwayBrowser/#/R-HSA-72619 eIF2:GTP is hydrolyzed, eIFs are released TAS Homo sapiens 2651 R-HSA-72621 https://reactome.org/PathwayBrowser/#/R-HSA-72621 Ribosomal scanning TAS Homo sapiens 2651 R-HSA-72669 https://reactome.org/PathwayBrowser/#/R-HSA-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex TAS Homo sapiens 2651 R-HSA-72671 https://reactome.org/PathwayBrowser/#/R-HSA-72671 eIF5B:GTP is hydrolyzed and released TAS Homo sapiens 2651 R-HSA-72672 https://reactome.org/PathwayBrowser/#/R-HSA-72672 The 60S subunit joins the translation initiation complex TAS Homo sapiens 2651 R-HSA-72691 https://reactome.org/PathwayBrowser/#/R-HSA-72691 Formation of the 43S pre-initiation complex TAS Homo sapiens 2651 R-HSA-72697 https://reactome.org/PathwayBrowser/#/R-HSA-72697 Start codon recognition TAS Homo sapiens 2651 R-MMU-156808 https://reactome.org/PathwayBrowser/#/R-MMU-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Mus musculus 2651 R-MMU-156823 https://reactome.org/PathwayBrowser/#/R-MMU-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Mus musculus 2651 R-MMU-157849 https://reactome.org/PathwayBrowser/#/R-MMU-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Mus musculus 2651 R-MMU-72619 https://reactome.org/PathwayBrowser/#/R-MMU-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Mus musculus 2651 R-MMU-72621 https://reactome.org/PathwayBrowser/#/R-MMU-72621 Ribosomal scanning IEA Mus musculus 2651 R-MMU-72669 https://reactome.org/PathwayBrowser/#/R-MMU-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Mus musculus 2651 R-MMU-72671 https://reactome.org/PathwayBrowser/#/R-MMU-72671 eIF5B:GTP is hydrolyzed and released IEA Mus musculus 2651 R-MMU-72672 https://reactome.org/PathwayBrowser/#/R-MMU-72672 The 60S subunit joins the translation initiation complex IEA Mus musculus 2651 R-MMU-72691 https://reactome.org/PathwayBrowser/#/R-MMU-72691 Formation of the 43S pre-initiation complex IEA Mus musculus 2651 R-MMU-72697 https://reactome.org/PathwayBrowser/#/R-MMU-72697 Start codon recognition IEA Mus musculus 2651 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 2651 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 2651 R-PFA-156808 https://reactome.org/PathwayBrowser/#/R-PFA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Plasmodium falciparum 2651 R-PFA-156823 https://reactome.org/PathwayBrowser/#/R-PFA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Plasmodium falciparum 2651 R-PFA-157849 https://reactome.org/PathwayBrowser/#/R-PFA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Plasmodium falciparum 2651 R-PFA-72621 https://reactome.org/PathwayBrowser/#/R-PFA-72621 Ribosomal scanning IEA Plasmodium falciparum 2651 R-PFA-72669 https://reactome.org/PathwayBrowser/#/R-PFA-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Plasmodium falciparum 2651 R-PFA-72671 https://reactome.org/PathwayBrowser/#/R-PFA-72671 eIF5B:GTP is hydrolyzed and released IEA Plasmodium falciparum 2651 R-PFA-72672 https://reactome.org/PathwayBrowser/#/R-PFA-72672 The 60S subunit joins the translation initiation complex IEA Plasmodium falciparum 2651 R-PFA-72691 https://reactome.org/PathwayBrowser/#/R-PFA-72691 Formation of the 43S pre-initiation complex IEA Plasmodium falciparum 2651 R-PFA-72697 https://reactome.org/PathwayBrowser/#/R-PFA-72697 Start codon recognition IEA Plasmodium falciparum 2651 R-RNO-156808 https://reactome.org/PathwayBrowser/#/R-RNO-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Rattus norvegicus 2651 R-RNO-156823 https://reactome.org/PathwayBrowser/#/R-RNO-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Rattus norvegicus 2651 R-RNO-157849 https://reactome.org/PathwayBrowser/#/R-RNO-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Rattus norvegicus 2651 R-RNO-2408535 https://reactome.org/PathwayBrowser/#/R-RNO-2408535 Sec-tRNA(Sec):Eefsec:GTP binds to Rpl30 TAS Rattus norvegicus 2651 R-RNO-5333610 https://reactome.org/PathwayBrowser/#/R-RNO-5333610 Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec-tRNA(Sec):Eefsec:GTP is hydrolysed to Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec and Eefsec:GDP by Eefsec TAS Rattus norvegicus 2651 R-RNO-72621 https://reactome.org/PathwayBrowser/#/R-RNO-72621 Ribosomal scanning IEA Rattus norvegicus 2651 R-RNO-72669 https://reactome.org/PathwayBrowser/#/R-RNO-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Rattus norvegicus 2651 R-RNO-72671 https://reactome.org/PathwayBrowser/#/R-RNO-72671 eIF5B:GTP is hydrolyzed and released IEA Rattus norvegicus 2651 R-RNO-72672 https://reactome.org/PathwayBrowser/#/R-RNO-72672 The 60S subunit joins the translation initiation complex IEA Rattus norvegicus 2651 R-RNO-72691 https://reactome.org/PathwayBrowser/#/R-RNO-72691 Formation of the 43S pre-initiation complex IEA Rattus norvegicus 2651 R-RNO-72697 https://reactome.org/PathwayBrowser/#/R-RNO-72697 Start codon recognition IEA Rattus norvegicus 2651 R-SCE-156808 https://reactome.org/PathwayBrowser/#/R-SCE-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Saccharomyces cerevisiae 2651 R-SCE-156823 https://reactome.org/PathwayBrowser/#/R-SCE-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Saccharomyces cerevisiae 2651 R-SCE-157849 https://reactome.org/PathwayBrowser/#/R-SCE-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Saccharomyces cerevisiae 2651 R-SCE-72621 https://reactome.org/PathwayBrowser/#/R-SCE-72621 Ribosomal scanning IEA Saccharomyces cerevisiae 2651 R-SCE-72669 https://reactome.org/PathwayBrowser/#/R-SCE-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Saccharomyces cerevisiae 2651 R-SCE-72671 https://reactome.org/PathwayBrowser/#/R-SCE-72671 eIF5B:GTP is hydrolyzed and released IEA Saccharomyces cerevisiae 2651 R-SCE-72672 https://reactome.org/PathwayBrowser/#/R-SCE-72672 The 60S subunit joins the translation initiation complex IEA Saccharomyces cerevisiae 2651 R-SCE-72691 https://reactome.org/PathwayBrowser/#/R-SCE-72691 Formation of the 43S pre-initiation complex IEA Saccharomyces cerevisiae 2651 R-SCE-72697 https://reactome.org/PathwayBrowser/#/R-SCE-72697 Start codon recognition IEA Saccharomyces cerevisiae 2651 R-SPO-156823 https://reactome.org/PathwayBrowser/#/R-SPO-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Schizosaccharomyces pombe 2651 R-SPO-157849 https://reactome.org/PathwayBrowser/#/R-SPO-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Schizosaccharomyces pombe 2651 R-SPO-72619 https://reactome.org/PathwayBrowser/#/R-SPO-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Schizosaccharomyces pombe 2651 R-SPO-72621 https://reactome.org/PathwayBrowser/#/R-SPO-72621 Ribosomal scanning IEA Schizosaccharomyces pombe 2651 R-SPO-72669 https://reactome.org/PathwayBrowser/#/R-SPO-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Schizosaccharomyces pombe 2651 R-SPO-72671 https://reactome.org/PathwayBrowser/#/R-SPO-72671 eIF5B:GTP is hydrolyzed and released IEA Schizosaccharomyces pombe 2651 R-SPO-72672 https://reactome.org/PathwayBrowser/#/R-SPO-72672 The 60S subunit joins the translation initiation complex IEA Schizosaccharomyces pombe 2651 R-SPO-72691 https://reactome.org/PathwayBrowser/#/R-SPO-72691 Formation of the 43S pre-initiation complex IEA Schizosaccharomyces pombe 2651 R-SPO-72697 https://reactome.org/PathwayBrowser/#/R-SPO-72697 Start codon recognition IEA Schizosaccharomyces pombe 2651 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa 2651 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa 2651 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa 2651 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa 2651 R-SSC-72669 https://reactome.org/PathwayBrowser/#/R-SSC-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Sus scrofa 2651 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa 2651 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa 2651 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa 2651 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa 2651 R-XTR-156823 https://reactome.org/PathwayBrowser/#/R-XTR-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Xenopus tropicalis 2651 R-XTR-72621 https://reactome.org/PathwayBrowser/#/R-XTR-72621 Ribosomal scanning IEA Xenopus tropicalis 2651 R-XTR-72669 https://reactome.org/PathwayBrowser/#/R-XTR-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Xenopus tropicalis 2651 R-XTR-72671 https://reactome.org/PathwayBrowser/#/R-XTR-72671 eIF5B:GTP is hydrolyzed and released IEA Xenopus tropicalis 2651 R-XTR-72672 https://reactome.org/PathwayBrowser/#/R-XTR-72672 The 60S subunit joins the translation initiation complex IEA Xenopus tropicalis 2651 R-XTR-72691 https://reactome.org/PathwayBrowser/#/R-XTR-72691 Formation of the 43S pre-initiation complex IEA Xenopus tropicalis 2651 R-XTR-72697 https://reactome.org/PathwayBrowser/#/R-XTR-72697 Start codon recognition IEA Xenopus tropicalis 26523 R-BTA-1250280 https://reactome.org/PathwayBrowser/#/R-BTA-1250280 ROS oxidize thioredoxin IEA Bos taurus 26523 R-BTA-3225851 https://reactome.org/PathwayBrowser/#/R-BTA-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Bos taurus 26523 R-BTA-9620515 https://reactome.org/PathwayBrowser/#/R-BTA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Bos taurus 26523 R-BTA-9664879 https://reactome.org/PathwayBrowser/#/R-BTA-9664879 ATM:PEX5 binds ATM IEA Bos taurus 26523 R-BTA-9708466 https://reactome.org/PathwayBrowser/#/R-BTA-9708466 p-Y483 BACH1 translocates from the nucleoplasm to the cytosol IEA Bos taurus 26523 R-BTA-9755505 https://reactome.org/PathwayBrowser/#/R-BTA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Bos taurus 26523 R-CEL-1250280 https://reactome.org/PathwayBrowser/#/R-CEL-1250280 ROS oxidize thioredoxin IEA Caenorhabditis elegans 26523 R-CEL-3225851 https://reactome.org/PathwayBrowser/#/R-CEL-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Caenorhabditis elegans 26523 R-CEL-9620515 https://reactome.org/PathwayBrowser/#/R-CEL-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Caenorhabditis elegans 26523 R-CEL-9755505 https://reactome.org/PathwayBrowser/#/R-CEL-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Caenorhabditis elegans 26523 R-CFA-1250280 https://reactome.org/PathwayBrowser/#/R-CFA-1250280 ROS oxidize thioredoxin IEA Canis familiaris 26523 R-CFA-3225851 https://reactome.org/PathwayBrowser/#/R-CFA-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Canis familiaris 26523 R-CFA-9620515 https://reactome.org/PathwayBrowser/#/R-CFA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Canis familiaris 26523 R-CFA-9664879 https://reactome.org/PathwayBrowser/#/R-CFA-9664879 ATM:PEX5 binds ATM IEA Canis familiaris 26523 R-CFA-9708466 https://reactome.org/PathwayBrowser/#/R-CFA-9708466 p-Y483 BACH1 translocates from the nucleoplasm to the cytosol IEA Canis familiaris 26523 R-CFA-9755505 https://reactome.org/PathwayBrowser/#/R-CFA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Canis familiaris 26523 R-DDI-1250280 https://reactome.org/PathwayBrowser/#/R-DDI-1250280 ROS oxidize thioredoxin IEA Dictyostelium discoideum 26523 R-DDI-9664879 https://reactome.org/PathwayBrowser/#/R-DDI-9664879 ATM:PEX5 binds ATM IEA Dictyostelium discoideum 26523 R-DDI-9755505 https://reactome.org/PathwayBrowser/#/R-DDI-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Dictyostelium discoideum 26523 R-DME-1250280 https://reactome.org/PathwayBrowser/#/R-DME-1250280 ROS oxidize thioredoxin IEA Drosophila melanogaster 26523 R-DME-3225851 https://reactome.org/PathwayBrowser/#/R-DME-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Drosophila melanogaster 26523 R-DME-9620515 https://reactome.org/PathwayBrowser/#/R-DME-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Drosophila melanogaster 26523 R-DME-9664879 https://reactome.org/PathwayBrowser/#/R-DME-9664879 ATM:PEX5 binds ATM IEA Drosophila melanogaster 26523 R-DME-9708466 https://reactome.org/PathwayBrowser/#/R-DME-9708466 p-Y483 BACH1 translocates from the nucleoplasm to the cytosol IEA Drosophila melanogaster 26523 R-DME-9755505 https://reactome.org/PathwayBrowser/#/R-DME-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Drosophila melanogaster 26523 R-DRE-1250280 https://reactome.org/PathwayBrowser/#/R-DRE-1250280 ROS oxidize thioredoxin IEA Danio rerio 26523 R-DRE-9620515 https://reactome.org/PathwayBrowser/#/R-DRE-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Danio rerio 26523 R-DRE-9755505 https://reactome.org/PathwayBrowser/#/R-DRE-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Danio rerio 26523 R-GGA-1250280 https://reactome.org/PathwayBrowser/#/R-GGA-1250280 ROS oxidize thioredoxin IEA Gallus gallus 26523 R-GGA-3225851 https://reactome.org/PathwayBrowser/#/R-GGA-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Gallus gallus 26523 R-GGA-9620515 https://reactome.org/PathwayBrowser/#/R-GGA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Gallus gallus 26523 R-GGA-9664879 https://reactome.org/PathwayBrowser/#/R-GGA-9664879 ATM:PEX5 binds ATM IEA Gallus gallus 26523 R-GGA-9708466 https://reactome.org/PathwayBrowser/#/R-GGA-9708466 p-Y483 BACH1 translocates from the nucleoplasm to the cytosol IEA Gallus gallus 26523 R-GGA-9755505 https://reactome.org/PathwayBrowser/#/R-GGA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Gallus gallus 26523 R-HSA-1250280 https://reactome.org/PathwayBrowser/#/R-HSA-1250280 ROS oxidize thioredoxin TAS Homo sapiens 26523 R-HSA-3223236 https://reactome.org/PathwayBrowser/#/R-HSA-3223236 RAS signaling and prolonged interferon-beta stimulation promote generation of reactive oxygen species (ROS) TAS Homo sapiens 26523 R-HSA-3225851 https://reactome.org/PathwayBrowser/#/R-HSA-3225851 ROS oxidize thioredoxin and activate MAP3K5 TAS Homo sapiens 26523 R-HSA-3225867 https://reactome.org/PathwayBrowser/#/R-HSA-3225867 Expression of MINK1/TNIK is positively regulated by ROS TAS Homo sapiens 26523 R-HSA-3785704 https://reactome.org/PathwayBrowser/#/R-HSA-3785704 DSB inducing agents induce double strand DNA breaks TAS Homo sapiens 26523 R-HSA-8932284 https://reactome.org/PathwayBrowser/#/R-HSA-8932284 PKC phosphorylates NFE2L2 IEA Homo sapiens 26523 R-HSA-8932322 https://reactome.org/PathwayBrowser/#/R-HSA-8932322 CK2 phosphorylates NFE2L2 IEA Homo sapiens 26523 R-HSA-9617660 https://reactome.org/PathwayBrowser/#/R-HSA-9617660 ROS oxidize FOXO4 cysteine residues IEA Homo sapiens 26523 R-HSA-9620515 https://reactome.org/PathwayBrowser/#/R-HSA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress TAS Homo sapiens 26523 R-HSA-9639698 https://reactome.org/PathwayBrowser/#/R-HSA-9639698 ROS positively regulates misfolding of cilia proteins IEA Homo sapiens 26523 R-HSA-9658813 https://reactome.org/PathwayBrowser/#/R-HSA-9658813 OGG1 S326C is oxidized TAS Homo sapiens 26523 R-HSA-9664879 https://reactome.org/PathwayBrowser/#/R-HSA-9664879 ATM:PEX5 binds ATM TAS Homo sapiens 26523 R-HSA-9708466 https://reactome.org/PathwayBrowser/#/R-HSA-9708466 p-Y483 BACH1 translocates from the nucleoplasm to the cytosol TAS Homo sapiens 26523 R-HSA-9755505 https://reactome.org/PathwayBrowser/#/R-HSA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 TAS Homo sapiens 26523 R-MMU-1250280 https://reactome.org/PathwayBrowser/#/R-MMU-1250280 ROS oxidize thioredoxin IEA Mus musculus 26523 R-MMU-3225851 https://reactome.org/PathwayBrowser/#/R-MMU-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Mus musculus 26523 R-MMU-8932375 https://reactome.org/PathwayBrowser/#/R-MMU-8932375 CK2 phosphorylates Nrf2 TAS Mus musculus 26523 R-MMU-9617657 https://reactome.org/PathwayBrowser/#/R-MMU-9617657 ROS oxidize Foxo4 cysteine residues TAS Mus musculus 26523 R-MMU-9620515 https://reactome.org/PathwayBrowser/#/R-MMU-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Mus musculus 26523 R-MMU-9639715 https://reactome.org/PathwayBrowser/#/R-MMU-9639715 ROS positively regulates misfolding of cilia proteins TAS Mus musculus 26523 R-MMU-9664879 https://reactome.org/PathwayBrowser/#/R-MMU-9664879 ATM:PEX5 binds ATM IEA Mus musculus 26523 R-MMU-9708466 https://reactome.org/PathwayBrowser/#/R-MMU-9708466 p-Y483 BACH1 translocates from the nucleoplasm to the cytosol IEA Mus musculus 26523 R-MMU-9755505 https://reactome.org/PathwayBrowser/#/R-MMU-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Mus musculus 26523 R-PFA-1250280 https://reactome.org/PathwayBrowser/#/R-PFA-1250280 ROS oxidize thioredoxin IEA Plasmodium falciparum 26523 R-RNO-1250280 https://reactome.org/PathwayBrowser/#/R-RNO-1250280 ROS oxidize thioredoxin IEA Rattus norvegicus 26523 R-RNO-3225851 https://reactome.org/PathwayBrowser/#/R-RNO-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Rattus norvegicus 26523 R-RNO-8932373 https://reactome.org/PathwayBrowser/#/R-RNO-8932373 PKC phosphorylates Nrf2 TAS Rattus norvegicus 26523 R-RNO-9620515 https://reactome.org/PathwayBrowser/#/R-RNO-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Rattus norvegicus 26523 R-RNO-9664879 https://reactome.org/PathwayBrowser/#/R-RNO-9664879 ATM:PEX5 binds ATM IEA Rattus norvegicus 26523 R-RNO-9708466 https://reactome.org/PathwayBrowser/#/R-RNO-9708466 p-Y483 BACH1 translocates from the nucleoplasm to the cytosol IEA Rattus norvegicus 26523 R-RNO-9755505 https://reactome.org/PathwayBrowser/#/R-RNO-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Rattus norvegicus 26523 R-SCE-1250280 https://reactome.org/PathwayBrowser/#/R-SCE-1250280 ROS oxidize thioredoxin IEA Saccharomyces cerevisiae 26523 R-SCE-3225851 https://reactome.org/PathwayBrowser/#/R-SCE-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Saccharomyces cerevisiae 26523 R-SCE-9664879 https://reactome.org/PathwayBrowser/#/R-SCE-9664879 ATM:PEX5 binds ATM IEA Saccharomyces cerevisiae 26523 R-SPO-1250280 https://reactome.org/PathwayBrowser/#/R-SPO-1250280 ROS oxidize thioredoxin IEA Schizosaccharomyces pombe 26523 R-SPO-3225851 https://reactome.org/PathwayBrowser/#/R-SPO-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Schizosaccharomyces pombe 26523 R-SPO-9664879 https://reactome.org/PathwayBrowser/#/R-SPO-9664879 ATM:PEX5 binds ATM IEA Schizosaccharomyces pombe 26523 R-SSC-1250280 https://reactome.org/PathwayBrowser/#/R-SSC-1250280 ROS oxidize thioredoxin IEA Sus scrofa 26523 R-SSC-3225851 https://reactome.org/PathwayBrowser/#/R-SSC-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Sus scrofa 26523 R-SSC-9620515 https://reactome.org/PathwayBrowser/#/R-SSC-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Sus scrofa 26523 R-SSC-9664879 https://reactome.org/PathwayBrowser/#/R-SSC-9664879 ATM:PEX5 binds ATM IEA Sus scrofa 26523 R-SSC-9708466 https://reactome.org/PathwayBrowser/#/R-SSC-9708466 p-Y483 BACH1 translocates from the nucleoplasm to the cytosol IEA Sus scrofa 26523 R-SSC-9755505 https://reactome.org/PathwayBrowser/#/R-SSC-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Sus scrofa 26523 R-XTR-9620515 https://reactome.org/PathwayBrowser/#/R-XTR-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Xenopus tropicalis 26523 R-XTR-9708466 https://reactome.org/PathwayBrowser/#/R-XTR-9708466 p-Y483 BACH1 translocates from the nucleoplasm to the cytosol IEA Xenopus tropicalis 26523 R-XTR-9755505 https://reactome.org/PathwayBrowser/#/R-XTR-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Xenopus tropicalis 26558 R-HSA-9682603 https://reactome.org/PathwayBrowser/#/R-HSA-9682603 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 26558 R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 26561 R-HSA-9836822 https://reactome.org/PathwayBrowser/#/R-HSA-9836822 REXO2 hydrolyzes 4-5 nucleotide RNAs to ribonucleotides TAS Homo sapiens 2663 R-BTA-9613570 https://reactome.org/PathwayBrowser/#/R-BTA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Bos taurus 2663 R-CEL-9613570 https://reactome.org/PathwayBrowser/#/R-CEL-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Caenorhabditis elegans 2663 R-CFA-9613570 https://reactome.org/PathwayBrowser/#/R-CFA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Canis familiaris 2663 R-DME-9613570 https://reactome.org/PathwayBrowser/#/R-DME-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Drosophila melanogaster 2663 R-GGA-9613570 https://reactome.org/PathwayBrowser/#/R-GGA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Gallus gallus 2663 R-HSA-9613570 https://reactome.org/PathwayBrowser/#/R-HSA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers TAS Homo sapiens 2663 R-MMU-9613570 https://reactome.org/PathwayBrowser/#/R-MMU-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Mus musculus 2663 R-PFA-9613570 https://reactome.org/PathwayBrowser/#/R-PFA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Plasmodium falciparum 2663 R-RNO-9613570 https://reactome.org/PathwayBrowser/#/R-RNO-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Rattus norvegicus 2663 R-SSC-9613570 https://reactome.org/PathwayBrowser/#/R-SSC-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Sus scrofa 2663 R-XTR-9613570 https://reactome.org/PathwayBrowser/#/R-XTR-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Xenopus tropicalis 26667 R-HSA-168272 https://reactome.org/PathwayBrowser/#/R-HSA-168272 Binding of the influenza virion to the host cell TAS Homo sapiens 26667 R-HSA-168285 https://reactome.org/PathwayBrowser/#/R-HSA-168285 Clathrin-Mediated Pit Formation And Endocytosis Of The Influenza Virion TAS Homo sapiens 26667 R-HSA-168860 https://reactome.org/PathwayBrowser/#/R-HSA-168860 Membrane fusion TAS Homo sapiens 26667 R-HSA-168870 https://reactome.org/PathwayBrowser/#/R-HSA-168870 Neuraminidase enzymatic release from sialic acid TAS Homo sapiens 2668 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 2668 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 2668 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 2668 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 2668 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 2668 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 2668 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 2668 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 2668 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 2668 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 26753 R-BTA-2404137 https://reactome.org/PathwayBrowser/#/R-BTA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 26753 R-BTA-2453855 https://reactome.org/PathwayBrowser/#/R-BTA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 26753 R-BTA-975608 https://reactome.org/PathwayBrowser/#/R-BTA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Bos taurus 26753 R-CFA-2404137 https://reactome.org/PathwayBrowser/#/R-CFA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 26753 R-CFA-2453855 https://reactome.org/PathwayBrowser/#/R-CFA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 26753 R-CFA-975608 https://reactome.org/PathwayBrowser/#/R-CFA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Canis familiaris 26753 R-DRE-2404137 https://reactome.org/PathwayBrowser/#/R-DRE-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 26753 R-DRE-2453855 https://reactome.org/PathwayBrowser/#/R-DRE-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 26753 R-DRE-975608 https://reactome.org/PathwayBrowser/#/R-DRE-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Danio rerio 26753 R-GGA-2404137 https://reactome.org/PathwayBrowser/#/R-GGA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 26753 R-GGA-2453855 https://reactome.org/PathwayBrowser/#/R-GGA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 26753 R-GGA-975608 https://reactome.org/PathwayBrowser/#/R-GGA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Gallus gallus 26753 R-HSA-2404137 https://reactome.org/PathwayBrowser/#/R-HSA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 26753 R-HSA-2453855 https://reactome.org/PathwayBrowser/#/R-HSA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 26753 R-HSA-2466710 https://reactome.org/PathwayBrowser/#/R-HSA-2466710 Defective LRAT does not esterify RBP1:atROL and FACYLs to atREs TAS Homo sapiens 26753 R-HSA-975608 https://reactome.org/PathwayBrowser/#/R-HSA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs TAS Homo sapiens 26753 R-MMU-2404137 https://reactome.org/PathwayBrowser/#/R-MMU-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 26753 R-MMU-2453855 https://reactome.org/PathwayBrowser/#/R-MMU-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 26753 R-MMU-975608 https://reactome.org/PathwayBrowser/#/R-MMU-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Mus musculus 26753 R-RNO-2404137 https://reactome.org/PathwayBrowser/#/R-RNO-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 26753 R-RNO-2453855 https://reactome.org/PathwayBrowser/#/R-RNO-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 26753 R-RNO-975608 https://reactome.org/PathwayBrowser/#/R-RNO-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Rattus norvegicus 26753 R-SSC-2404137 https://reactome.org/PathwayBrowser/#/R-SSC-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 26753 R-SSC-2453855 https://reactome.org/PathwayBrowser/#/R-SSC-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 26753 R-SSC-975608 https://reactome.org/PathwayBrowser/#/R-SSC-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Sus scrofa 26753 R-XTR-2404137 https://reactome.org/PathwayBrowser/#/R-XTR-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 26753 R-XTR-2453855 https://reactome.org/PathwayBrowser/#/R-XTR-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 26753 R-XTR-975608 https://reactome.org/PathwayBrowser/#/R-XTR-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Xenopus tropicalis 26756 R-HSA-9661726 https://reactome.org/PathwayBrowser/#/R-HSA-9661726 An unknown reductase reduces D-UBGN to STBN TAS Homo sapiens 26833 R-HSA-2564826 https://reactome.org/PathwayBrowser/#/R-HSA-2564826 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold IEA Homo sapiens 26833 R-SCE-2564822 https://reactome.org/PathwayBrowser/#/R-SCE-2564822 4Fe-4S cluster assembles on CFD1:NBP35 scaffold TAS Saccharomyces cerevisiae 26948 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 26948 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 26948 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 26948 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 26948 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 26948 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 26948 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 26948 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 26948 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 26948 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 26948 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 26948 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 26948 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 26948 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 26948 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 26948 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 26948 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 26948 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 26948 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 26948 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 26948 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 26948 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 26948 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 26948 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 26948 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 26948 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 26948 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 26948 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 26948 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 26948 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 26948 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 26948 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 26948 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 26948 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 26948 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 26948 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 26948 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 26948 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 26948 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 26948 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 26948 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 26948 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 2700 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2700 R-BTA-419426 https://reactome.org/PathwayBrowser/#/R-BTA-419426 Cannabinoid receptors can bind cannabinoids IEA Bos taurus 2700 R-BTA-5693742 https://reactome.org/PathwayBrowser/#/R-BTA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Bos taurus 2700 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 2700 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2700 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2700 R-CEL-5693742 https://reactome.org/PathwayBrowser/#/R-CEL-5693742 FAAH hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 2700 R-CEL-5693751 https://reactome.org/PathwayBrowser/#/R-CEL-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 2700 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 2700 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2700 R-CFA-419426 https://reactome.org/PathwayBrowser/#/R-CFA-419426 Cannabinoid receptors can bind cannabinoids IEA Canis familiaris 2700 R-CFA-5693742 https://reactome.org/PathwayBrowser/#/R-CFA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Canis familiaris 2700 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2700 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2700 R-DME-5693751 https://reactome.org/PathwayBrowser/#/R-DME-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Drosophila melanogaster 2700 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2700 R-DRE-419426 https://reactome.org/PathwayBrowser/#/R-DRE-419426 Cannabinoid receptors can bind cannabinoids IEA Danio rerio 2700 R-DRE-5693751 https://reactome.org/PathwayBrowser/#/R-DRE-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Danio rerio 2700 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2700 R-GGA-419426 https://reactome.org/PathwayBrowser/#/R-GGA-419426 Cannabinoid receptors can bind cannabinoids IEA Gallus gallus 2700 R-GGA-5693742 https://reactome.org/PathwayBrowser/#/R-GGA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Gallus gallus 2700 R-GGA-5693751 https://reactome.org/PathwayBrowser/#/R-GGA-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Gallus gallus 2700 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 2700 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 2700 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2700 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2700 R-HSA-419426 https://reactome.org/PathwayBrowser/#/R-HSA-419426 Cannabinoid receptors can bind cannabinoids TAS Homo sapiens 2700 R-HSA-5693742 https://reactome.org/PathwayBrowser/#/R-HSA-5693742 FAAH hydrolyses AEA to AA and ETA TAS Homo sapiens 2700 R-HSA-5693751 https://reactome.org/PathwayBrowser/#/R-HSA-5693751 FAAH2 hydrolyses AEA to AA and ETA TAS Homo sapiens 2700 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 2700 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2700 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2700 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2700 R-MMU-419426 https://reactome.org/PathwayBrowser/#/R-MMU-419426 Cannabinoid receptors can bind cannabinoids IEA Mus musculus 2700 R-MMU-5693742 https://reactome.org/PathwayBrowser/#/R-MMU-5693742 FAAH hydrolyses AEA to AA and ETA IEA Mus musculus 2700 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 2700 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2700 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2700 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2700 R-RNO-419426 https://reactome.org/PathwayBrowser/#/R-RNO-419426 Cannabinoid receptors can bind cannabinoids IEA Rattus norvegicus 2700 R-RNO-5693742 https://reactome.org/PathwayBrowser/#/R-RNO-5693742 FAAH hydrolyses AEA to AA and ETA IEA Rattus norvegicus 2700 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 2700 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2700 R-SSC-419426 https://reactome.org/PathwayBrowser/#/R-SSC-419426 Cannabinoid receptors can bind cannabinoids IEA Sus scrofa 2700 R-SSC-5693742 https://reactome.org/PathwayBrowser/#/R-SSC-5693742 FAAH hydrolyses AEA to AA and ETA IEA Sus scrofa 2700 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 2700 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2700 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2700 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2700 R-XTR-419426 https://reactome.org/PathwayBrowser/#/R-XTR-419426 Cannabinoid receptors can bind cannabinoids IEA Xenopus tropicalis 2700 R-XTR-5693742 https://reactome.org/PathwayBrowser/#/R-XTR-5693742 FAAH hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 2700 R-XTR-5693751 https://reactome.org/PathwayBrowser/#/R-XTR-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 2700 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 2700 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 2700 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 27283 R-BTA-5696007 https://reactome.org/PathwayBrowser/#/R-BTA-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Bos taurus 27283 R-CFA-5695957 https://reactome.org/PathwayBrowser/#/R-CFA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Canis familiaris 27283 R-DDI-5695957 https://reactome.org/PathwayBrowser/#/R-DDI-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Dictyostelium discoideum 27283 R-DDI-5696007 https://reactome.org/PathwayBrowser/#/R-DDI-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Dictyostelium discoideum 27283 R-DME-5695957 https://reactome.org/PathwayBrowser/#/R-DME-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Drosophila melanogaster 27283 R-DME-5696007 https://reactome.org/PathwayBrowser/#/R-DME-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Drosophila melanogaster 27283 R-GGA-5695957 https://reactome.org/PathwayBrowser/#/R-GGA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Gallus gallus 27283 R-HSA-5695957 https://reactome.org/PathwayBrowser/#/R-HSA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA TAS Homo sapiens 27283 R-HSA-5696007 https://reactome.org/PathwayBrowser/#/R-HSA-5696007 ACSF3 ligates CoA-SH to VLCFA TAS Homo sapiens 27283 R-HSA-8875077 https://reactome.org/PathwayBrowser/#/R-HSA-8875077 SLC27A3 ligates CoA-SH to VLCFA IEA Homo sapiens 27283 R-MMU-5695957 https://reactome.org/PathwayBrowser/#/R-MMU-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Mus musculus 27283 R-MMU-5696007 https://reactome.org/PathwayBrowser/#/R-MMU-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Mus musculus 27283 R-MMU-8875095 https://reactome.org/PathwayBrowser/#/R-MMU-8875095 Slc27a3 ligates CoA to VLCFA TAS Mus musculus 27283 R-RNO-5695957 https://reactome.org/PathwayBrowser/#/R-RNO-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Rattus norvegicus 27283 R-RNO-5696007 https://reactome.org/PathwayBrowser/#/R-RNO-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Rattus norvegicus 27283 R-SSC-5695957 https://reactome.org/PathwayBrowser/#/R-SSC-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Sus scrofa 27283 R-SSC-5696007 https://reactome.org/PathwayBrowser/#/R-SSC-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Sus scrofa 27372 R-BTA-429571 https://reactome.org/PathwayBrowser/#/R-BTA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Bos taurus 27372 R-CFA-429571 https://reactome.org/PathwayBrowser/#/R-CFA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Canis familiaris 27372 R-DRE-429571 https://reactome.org/PathwayBrowser/#/R-DRE-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Danio rerio 27372 R-GGA-429571 https://reactome.org/PathwayBrowser/#/R-GGA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Gallus gallus 27372 R-HSA-429571 https://reactome.org/PathwayBrowser/#/R-HSA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 TAS Homo sapiens 27372 R-MMU-429571 https://reactome.org/PathwayBrowser/#/R-MMU-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Mus musculus 27372 R-RNO-429571 https://reactome.org/PathwayBrowser/#/R-RNO-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Rattus norvegicus 27372 R-SSC-429571 https://reactome.org/PathwayBrowser/#/R-SSC-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Sus scrofa 27372 R-XTR-429571 https://reactome.org/PathwayBrowser/#/R-XTR-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Xenopus tropicalis 27379 R-BTA-192341 https://reactome.org/PathwayBrowser/#/R-BTA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Bos taurus 27379 R-BTA-193455 https://reactome.org/PathwayBrowser/#/R-BTA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 27379 R-CEL-193455 https://reactome.org/PathwayBrowser/#/R-CEL-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 27379 R-CFA-192341 https://reactome.org/PathwayBrowser/#/R-CFA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Canis familiaris 27379 R-CFA-193455 https://reactome.org/PathwayBrowser/#/R-CFA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 27379 R-DDI-193455 https://reactome.org/PathwayBrowser/#/R-DDI-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 27379 R-DME-192341 https://reactome.org/PathwayBrowser/#/R-DME-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Drosophila melanogaster 27379 R-DME-193455 https://reactome.org/PathwayBrowser/#/R-DME-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 27379 R-DRE-192341 https://reactome.org/PathwayBrowser/#/R-DRE-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Danio rerio 27379 R-GGA-192341 https://reactome.org/PathwayBrowser/#/R-GGA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Gallus gallus 27379 R-GGA-193455 https://reactome.org/PathwayBrowser/#/R-GGA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 27379 R-HSA-192341 https://reactome.org/PathwayBrowser/#/R-HSA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA TAS Homo sapiens 27379 R-HSA-193455 https://reactome.org/PathwayBrowser/#/R-HSA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 27379 R-MMU-192341 https://reactome.org/PathwayBrowser/#/R-MMU-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Mus musculus 27379 R-MMU-193455 https://reactome.org/PathwayBrowser/#/R-MMU-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 27379 R-RNO-192341 https://reactome.org/PathwayBrowser/#/R-RNO-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Rattus norvegicus 27379 R-RNO-193455 https://reactome.org/PathwayBrowser/#/R-RNO-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 27384 R-BTA-70903 https://reactome.org/PathwayBrowser/#/R-BTA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Bos taurus 27384 R-BTA-70906 https://reactome.org/PathwayBrowser/#/R-BTA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Bos taurus 27384 R-CEL-70903 https://reactome.org/PathwayBrowser/#/R-CEL-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Caenorhabditis elegans 27384 R-CEL-70906 https://reactome.org/PathwayBrowser/#/R-CEL-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Caenorhabditis elegans 27384 R-CFA-70903 https://reactome.org/PathwayBrowser/#/R-CFA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Canis familiaris 27384 R-CFA-70906 https://reactome.org/PathwayBrowser/#/R-CFA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Canis familiaris 27384 R-DDI-70903 https://reactome.org/PathwayBrowser/#/R-DDI-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Dictyostelium discoideum 27384 R-DDI-70906 https://reactome.org/PathwayBrowser/#/R-DDI-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Dictyostelium discoideum 27384 R-DRE-70903 https://reactome.org/PathwayBrowser/#/R-DRE-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Danio rerio 27384 R-DRE-70906 https://reactome.org/PathwayBrowser/#/R-DRE-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Danio rerio 27384 R-GGA-70903 https://reactome.org/PathwayBrowser/#/R-GGA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Gallus gallus 27384 R-GGA-70906 https://reactome.org/PathwayBrowser/#/R-GGA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Gallus gallus 27384 R-HSA-70903 https://reactome.org/PathwayBrowser/#/R-HSA-70903 urocanate + H2O => 4-imidazolone-5-propionate TAS Homo sapiens 27384 R-HSA-70906 https://reactome.org/PathwayBrowser/#/R-HSA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ TAS Homo sapiens 27384 R-MMU-70903 https://reactome.org/PathwayBrowser/#/R-MMU-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Mus musculus 27384 R-MMU-70906 https://reactome.org/PathwayBrowser/#/R-MMU-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Mus musculus 27384 R-RNO-70903 https://reactome.org/PathwayBrowser/#/R-RNO-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Rattus norvegicus 27384 R-RNO-70906 https://reactome.org/PathwayBrowser/#/R-RNO-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Rattus norvegicus 27384 R-SSC-70903 https://reactome.org/PathwayBrowser/#/R-SSC-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Sus scrofa 27384 R-SSC-70906 https://reactome.org/PathwayBrowser/#/R-SSC-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Sus scrofa 27384 R-XTR-70903 https://reactome.org/PathwayBrowser/#/R-XTR-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Xenopus tropicalis 27384 R-XTR-70906 https://reactome.org/PathwayBrowser/#/R-XTR-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ IEA Xenopus tropicalis 27385 R-BTA-76434 https://reactome.org/PathwayBrowser/#/R-BTA-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Bos taurus 27385 R-CEL-76434 https://reactome.org/PathwayBrowser/#/R-CEL-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Caenorhabditis elegans 27385 R-CFA-76434 https://reactome.org/PathwayBrowser/#/R-CFA-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Canis familiaris 27385 R-DDI-76434 https://reactome.org/PathwayBrowser/#/R-DDI-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Dictyostelium discoideum 27385 R-DME-76434 https://reactome.org/PathwayBrowser/#/R-DME-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Drosophila melanogaster 27385 R-DRE-76434 https://reactome.org/PathwayBrowser/#/R-DRE-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Danio rerio 27385 R-GGA-76434 https://reactome.org/PathwayBrowser/#/R-GGA-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Gallus gallus 27385 R-HSA-76434 https://reactome.org/PathwayBrowser/#/R-HSA-76434 Dehalogenation of carbon tetrachloride to form a free radical TAS Homo sapiens 27385 R-MMU-76434 https://reactome.org/PathwayBrowser/#/R-MMU-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Mus musculus 27385 R-RNO-76434 https://reactome.org/PathwayBrowser/#/R-RNO-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Rattus norvegicus 27385 R-SSC-76434 https://reactome.org/PathwayBrowser/#/R-SSC-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Sus scrofa 27385 R-XTR-76434 https://reactome.org/PathwayBrowser/#/R-XTR-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Xenopus tropicalis 27393 R-BTA-193369 https://reactome.org/PathwayBrowser/#/R-BTA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Bos taurus 27393 R-BTA-193535 https://reactome.org/PathwayBrowser/#/R-BTA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Bos taurus 27393 R-CEL-193369 https://reactome.org/PathwayBrowser/#/R-CEL-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Caenorhabditis elegans 27393 R-CEL-193535 https://reactome.org/PathwayBrowser/#/R-CEL-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Caenorhabditis elegans 27393 R-CFA-193369 https://reactome.org/PathwayBrowser/#/R-CFA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Canis familiaris 27393 R-CFA-193535 https://reactome.org/PathwayBrowser/#/R-CFA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Canis familiaris 27393 R-DDI-193369 https://reactome.org/PathwayBrowser/#/R-DDI-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Dictyostelium discoideum 27393 R-DDI-193535 https://reactome.org/PathwayBrowser/#/R-DDI-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Dictyostelium discoideum 27393 R-DME-193369 https://reactome.org/PathwayBrowser/#/R-DME-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Drosophila melanogaster 27393 R-DME-193535 https://reactome.org/PathwayBrowser/#/R-DME-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Drosophila melanogaster 27393 R-GGA-193369 https://reactome.org/PathwayBrowser/#/R-GGA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Gallus gallus 27393 R-GGA-193535 https://reactome.org/PathwayBrowser/#/R-GGA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Gallus gallus 27393 R-HSA-193369 https://reactome.org/PathwayBrowser/#/R-HSA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA TAS Homo sapiens 27393 R-HSA-193535 https://reactome.org/PathwayBrowser/#/R-HSA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA TAS Homo sapiens 27393 R-MMU-193369 https://reactome.org/PathwayBrowser/#/R-MMU-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Mus musculus 27393 R-MMU-193535 https://reactome.org/PathwayBrowser/#/R-MMU-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Mus musculus 27393 R-RNO-193369 https://reactome.org/PathwayBrowser/#/R-RNO-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Rattus norvegicus 27393 R-RNO-193535 https://reactome.org/PathwayBrowser/#/R-RNO-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Rattus norvegicus 27393 R-SSC-193369 https://reactome.org/PathwayBrowser/#/R-SSC-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Sus scrofa 27393 R-XTR-193369 https://reactome.org/PathwayBrowser/#/R-XTR-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Xenopus tropicalis 27398 R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 27398 R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 27398 R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 27398 R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 27398 R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 27398 R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 27398 R-SSC-5696131 https://reactome.org/PathwayBrowser/#/R-SSC-5696131 AOC1 deaminates Hist IEA Sus scrofa 27398 R-XTR-5696131 https://reactome.org/PathwayBrowser/#/R-XTR-5696131 AOC1 deaminates Hist IEA Xenopus tropicalis 27402 R-BTA-77301 https://reactome.org/PathwayBrowser/#/R-BTA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Bos taurus 27402 R-BTA-77303 https://reactome.org/PathwayBrowser/#/R-BTA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Bos taurus 27402 R-CEL-77301 https://reactome.org/PathwayBrowser/#/R-CEL-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Caenorhabditis elegans 27402 R-CEL-77303 https://reactome.org/PathwayBrowser/#/R-CEL-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Caenorhabditis elegans 27402 R-CFA-77301 https://reactome.org/PathwayBrowser/#/R-CFA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Canis familiaris 27402 R-CFA-77303 https://reactome.org/PathwayBrowser/#/R-CFA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Canis familiaris 27402 R-DME-77301 https://reactome.org/PathwayBrowser/#/R-DME-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Drosophila melanogaster 27402 R-DME-77303 https://reactome.org/PathwayBrowser/#/R-DME-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Drosophila melanogaster 27402 R-DRE-77301 https://reactome.org/PathwayBrowser/#/R-DRE-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Danio rerio 27402 R-DRE-77303 https://reactome.org/PathwayBrowser/#/R-DRE-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Danio rerio 27402 R-GGA-77301 https://reactome.org/PathwayBrowser/#/R-GGA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Gallus gallus 27402 R-GGA-77303 https://reactome.org/PathwayBrowser/#/R-GGA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Gallus gallus 27402 R-HSA-77301 https://reactome.org/PathwayBrowser/#/R-HSA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA TAS Homo sapiens 27402 R-HSA-77303 https://reactome.org/PathwayBrowser/#/R-HSA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H TAS Homo sapiens 27402 R-MMU-77301 https://reactome.org/PathwayBrowser/#/R-MMU-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Mus musculus 27402 R-MMU-77303 https://reactome.org/PathwayBrowser/#/R-MMU-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Mus musculus 27402 R-RNO-77301 https://reactome.org/PathwayBrowser/#/R-RNO-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Rattus norvegicus 27402 R-RNO-77303 https://reactome.org/PathwayBrowser/#/R-RNO-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Rattus norvegicus 27402 R-SSC-77301 https://reactome.org/PathwayBrowser/#/R-SSC-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Sus scrofa 27402 R-SSC-77303 https://reactome.org/PathwayBrowser/#/R-SSC-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Sus scrofa 27402 R-XTR-77301 https://reactome.org/PathwayBrowser/#/R-XTR-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Xenopus tropicalis 27402 R-XTR-77303 https://reactome.org/PathwayBrowser/#/R-XTR-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Xenopus tropicalis 27403 R-BTA-193508 https://reactome.org/PathwayBrowser/#/R-BTA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 27403 R-BTA-193535 https://reactome.org/PathwayBrowser/#/R-BTA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Bos taurus 27403 R-BTA-193711 https://reactome.org/PathwayBrowser/#/R-BTA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 27403 R-BTA-193736 https://reactome.org/PathwayBrowser/#/R-BTA-193736 Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Bos taurus 27403 R-BTA-193743 https://reactome.org/PathwayBrowser/#/R-BTA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 27403 R-CEL-193508 https://reactome.org/PathwayBrowser/#/R-CEL-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 27403 R-CEL-193535 https://reactome.org/PathwayBrowser/#/R-CEL-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Caenorhabditis elegans 27403 R-CEL-193711 https://reactome.org/PathwayBrowser/#/R-CEL-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 27403 R-CEL-193736 https://reactome.org/PathwayBrowser/#/R-CEL-193736 Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Caenorhabditis elegans 27403 R-CEL-193743 https://reactome.org/PathwayBrowser/#/R-CEL-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 27403 R-CFA-193508 https://reactome.org/PathwayBrowser/#/R-CFA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 27403 R-CFA-193535 https://reactome.org/PathwayBrowser/#/R-CFA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Canis familiaris 27403 R-CFA-193711 https://reactome.org/PathwayBrowser/#/R-CFA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 27403 R-CFA-193743 https://reactome.org/PathwayBrowser/#/R-CFA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 27403 R-DDI-193508 https://reactome.org/PathwayBrowser/#/R-DDI-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 27403 R-DDI-193535 https://reactome.org/PathwayBrowser/#/R-DDI-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Dictyostelium discoideum 27403 R-DME-193508 https://reactome.org/PathwayBrowser/#/R-DME-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 27403 R-DME-193535 https://reactome.org/PathwayBrowser/#/R-DME-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Drosophila melanogaster 27403 R-DME-193711 https://reactome.org/PathwayBrowser/#/R-DME-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 27403 R-DME-193736 https://reactome.org/PathwayBrowser/#/R-DME-193736 Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Drosophila melanogaster 27403 R-DME-193743 https://reactome.org/PathwayBrowser/#/R-DME-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 27403 R-DRE-193711 https://reactome.org/PathwayBrowser/#/R-DRE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 27403 R-DRE-193736 https://reactome.org/PathwayBrowser/#/R-DRE-193736 Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Danio rerio 27403 R-GGA-193508 https://reactome.org/PathwayBrowser/#/R-GGA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 27403 R-GGA-193535 https://reactome.org/PathwayBrowser/#/R-GGA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Gallus gallus 27403 R-GGA-193711 https://reactome.org/PathwayBrowser/#/R-GGA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 27403 R-GGA-193736 https://reactome.org/PathwayBrowser/#/R-GGA-193736 Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Gallus gallus 27403 R-GGA-193743 https://reactome.org/PathwayBrowser/#/R-GGA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 27403 R-HSA-193508 https://reactome.org/PathwayBrowser/#/R-HSA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 27403 R-HSA-193535 https://reactome.org/PathwayBrowser/#/R-HSA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA TAS Homo sapiens 27403 R-HSA-193711 https://reactome.org/PathwayBrowser/#/R-HSA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 27403 R-HSA-193736 https://reactome.org/PathwayBrowser/#/R-HSA-193736 Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA TAS Homo sapiens 27403 R-HSA-193743 https://reactome.org/PathwayBrowser/#/R-HSA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 27403 R-HSA-193753 https://reactome.org/PathwayBrowser/#/R-HSA-193753 3,7,24THCA-CoA is translocated from the cytosol to the peroxisome TAS Homo sapiens 27403 R-MMU-193508 https://reactome.org/PathwayBrowser/#/R-MMU-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 27403 R-MMU-193535 https://reactome.org/PathwayBrowser/#/R-MMU-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Mus musculus 27403 R-MMU-193711 https://reactome.org/PathwayBrowser/#/R-MMU-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 27403 R-MMU-193736 https://reactome.org/PathwayBrowser/#/R-MMU-193736 Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Mus musculus 27403 R-MMU-193743 https://reactome.org/PathwayBrowser/#/R-MMU-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 27403 R-RNO-193508 https://reactome.org/PathwayBrowser/#/R-RNO-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 27403 R-RNO-193535 https://reactome.org/PathwayBrowser/#/R-RNO-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Rattus norvegicus 27403 R-RNO-193711 https://reactome.org/PathwayBrowser/#/R-RNO-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 27403 R-RNO-193736 https://reactome.org/PathwayBrowser/#/R-RNO-193736 Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Rattus norvegicus 27403 R-RNO-193743 https://reactome.org/PathwayBrowser/#/R-RNO-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 27403 R-SCE-193711 https://reactome.org/PathwayBrowser/#/R-SCE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 27403 R-SCE-193743 https://reactome.org/PathwayBrowser/#/R-SCE-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 27403 R-SSC-193711 https://reactome.org/PathwayBrowser/#/R-SSC-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 27403 R-SSC-193743 https://reactome.org/PathwayBrowser/#/R-SSC-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 27403 R-XTR-193711 https://reactome.org/PathwayBrowser/#/R-XTR-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 27403 R-XTR-193736 https://reactome.org/PathwayBrowser/#/R-XTR-193736 Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Xenopus tropicalis 27403 R-XTR-193743 https://reactome.org/PathwayBrowser/#/R-XTR-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 27404 R-BTA-5663050 https://reactome.org/PathwayBrowser/#/R-BTA-5663050 DHI and DHICA polymerize forming eumelanin IEA Bos taurus 27404 R-CEL-5663050 https://reactome.org/PathwayBrowser/#/R-CEL-5663050 DHI and DHICA polymerize forming eumelanin IEA Caenorhabditis elegans 27404 R-CFA-5663050 https://reactome.org/PathwayBrowser/#/R-CFA-5663050 DHI and DHICA polymerize forming eumelanin IEA Canis familiaris 27404 R-DDI-5663050 https://reactome.org/PathwayBrowser/#/R-DDI-5663050 DHI and DHICA polymerize forming eumelanin IEA Dictyostelium discoideum 27404 R-GGA-5663050 https://reactome.org/PathwayBrowser/#/R-GGA-5663050 DHI and DHICA polymerize forming eumelanin IEA Gallus gallus 27404 R-HSA-5662706 https://reactome.org/PathwayBrowser/#/R-HSA-5662706 Dopachrome transforms to DHI TAS Homo sapiens 27404 R-HSA-5663050 https://reactome.org/PathwayBrowser/#/R-HSA-5663050 DHI and DHICA polymerize forming eumelanin TAS Homo sapiens 27404 R-MMU-5663050 https://reactome.org/PathwayBrowser/#/R-MMU-5663050 DHI and DHICA polymerize forming eumelanin IEA Mus musculus 27404 R-RNO-5663050 https://reactome.org/PathwayBrowser/#/R-RNO-5663050 DHI and DHICA polymerize forming eumelanin IEA Rattus norvegicus 27404 R-SSC-5663050 https://reactome.org/PathwayBrowser/#/R-SSC-5663050 DHI and DHICA polymerize forming eumelanin IEA Sus scrofa 27404 R-XTR-5663050 https://reactome.org/PathwayBrowser/#/R-XTR-5663050 DHI and DHICA polymerize forming eumelanin IEA Xenopus tropicalis 27428 R-BTA-193460 https://reactome.org/PathwayBrowser/#/R-BTA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Bos taurus 27428 R-BTA-193497 https://reactome.org/PathwayBrowser/#/R-BTA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Bos taurus 27428 R-CFA-193460 https://reactome.org/PathwayBrowser/#/R-CFA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Canis familiaris 27428 R-CFA-193497 https://reactome.org/PathwayBrowser/#/R-CFA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Canis familiaris 27428 R-HSA-193460 https://reactome.org/PathwayBrowser/#/R-HSA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) TAS Homo sapiens 27428 R-HSA-193497 https://reactome.org/PathwayBrowser/#/R-HSA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al TAS Homo sapiens 27428 R-MMU-193460 https://reactome.org/PathwayBrowser/#/R-MMU-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Mus musculus 27428 R-MMU-193497 https://reactome.org/PathwayBrowser/#/R-MMU-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Mus musculus 27428 R-RNO-193460 https://reactome.org/PathwayBrowser/#/R-RNO-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Rattus norvegicus 27428 R-RNO-193497 https://reactome.org/PathwayBrowser/#/R-RNO-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Rattus norvegicus 27428 R-SSC-193460 https://reactome.org/PathwayBrowser/#/R-SSC-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Sus scrofa 27428 R-SSC-193497 https://reactome.org/PathwayBrowser/#/R-SSC-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Sus scrofa 27432 R-BTA-2046085 https://reactome.org/PathwayBrowser/#/R-BTA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Bos taurus 27432 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 27432 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 27432 R-BTA-400143 https://reactome.org/PathwayBrowser/#/R-BTA-400143 Fatty acid ligands activate PPARA IEA Bos taurus 27432 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 27432 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 27432 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 27432 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 27432 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 27432 R-CFA-2046085 https://reactome.org/PathwayBrowser/#/R-CFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Canis familiaris 27432 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 27432 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 27432 R-CFA-400143 https://reactome.org/PathwayBrowser/#/R-CFA-400143 Fatty acid ligands activate PPARA IEA Canis familiaris 27432 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 27432 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 27432 R-DDI-2046085 https://reactome.org/PathwayBrowser/#/R-DDI-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Dictyostelium discoideum 27432 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 27432 R-DME-400143 https://reactome.org/PathwayBrowser/#/R-DME-400143 Fatty acid ligands activate PPARA IEA Drosophila melanogaster 27432 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 27432 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 27432 R-DRE-2046085 https://reactome.org/PathwayBrowser/#/R-DRE-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Danio rerio 27432 R-DRE-400143 https://reactome.org/PathwayBrowser/#/R-DRE-400143 Fatty acid ligands activate PPARA IEA Danio rerio 27432 R-GGA-2046085 https://reactome.org/PathwayBrowser/#/R-GGA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Gallus gallus 27432 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 27432 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 27432 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus 27432 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 27432 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 27432 R-HSA-1368065 https://reactome.org/PathwayBrowser/#/R-HSA-1368065 Expression of NPAS2 IEA Homo sapiens 27432 R-HSA-1592238 https://reactome.org/PathwayBrowser/#/R-HSA-1592238 Expression of ALAS1 TAS Homo sapiens 27432 R-HSA-1655826 https://reactome.org/PathwayBrowser/#/R-HSA-1655826 Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) TAS Homo sapiens 27432 R-HSA-1655848 https://reactome.org/PathwayBrowser/#/R-HSA-1655848 Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) TAS Homo sapiens 27432 R-HSA-1655850 https://reactome.org/PathwayBrowser/#/R-HSA-1655850 Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) TAS Homo sapiens 27432 R-HSA-1801587 https://reactome.org/PathwayBrowser/#/R-HSA-1801587 Expression of CPT1A IEA Homo sapiens 27432 R-HSA-1989745 https://reactome.org/PathwayBrowser/#/R-HSA-1989745 Expression of ACADM TAS Homo sapiens 27432 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 27432 R-HSA-1989747 https://reactome.org/PathwayBrowser/#/R-HSA-1989747 Expression of FHL2 TAS Homo sapiens 27432 R-HSA-1989748 https://reactome.org/PathwayBrowser/#/R-HSA-1989748 Expression of GRHL1 TAS Homo sapiens 27432 R-HSA-1989749 https://reactome.org/PathwayBrowser/#/R-HSA-1989749 Expression of ACOX1 TAS Homo sapiens 27432 R-HSA-1989750 https://reactome.org/PathwayBrowser/#/R-HSA-1989750 Expression of FATP1 (SLC27A1) TAS Homo sapiens 27432 R-HSA-1989751 https://reactome.org/PathwayBrowser/#/R-HSA-1989751 Expression of FABP1 TAS Homo sapiens 27432 R-HSA-1989752 https://reactome.org/PathwayBrowser/#/R-HSA-1989752 Expression of TXNRD1 TAS Homo sapiens 27432 R-HSA-1989753 https://reactome.org/PathwayBrowser/#/R-HSA-1989753 Expression of PEX11A TAS Homo sapiens 27432 R-HSA-1989754 https://reactome.org/PathwayBrowser/#/R-HSA-1989754 Expression of APOA1 TAS Homo sapiens 27432 R-HSA-1989755 https://reactome.org/PathwayBrowser/#/R-HSA-1989755 Expression of CYP4A11 TAS Homo sapiens 27432 R-HSA-1989756 https://reactome.org/PathwayBrowser/#/R-HSA-1989756 Expression of ME1 TAS Homo sapiens 27432 R-HSA-1989757 https://reactome.org/PathwayBrowser/#/R-HSA-1989757 Expression of FADS1 TAS Homo sapiens 27432 R-HSA-1989758 https://reactome.org/PathwayBrowser/#/R-HSA-1989758 Expression of UGT1A9 TAS Homo sapiens 27432 R-HSA-1989759 https://reactome.org/PathwayBrowser/#/R-HSA-1989759 Expression of G0S2 TAS Homo sapiens 27432 R-HSA-1989760 https://reactome.org/PathwayBrowser/#/R-HSA-1989760 Expression of HMGCS2 TAS Homo sapiens 27432 R-HSA-1989761 https://reactome.org/PathwayBrowser/#/R-HSA-1989761 Expression of APOA5 TAS Homo sapiens 27432 R-HSA-1989762 https://reactome.org/PathwayBrowser/#/R-HSA-1989762 Expression of ABCB4 TAS Homo sapiens 27432 R-HSA-1989764 https://reactome.org/PathwayBrowser/#/R-HSA-1989764 Expression of CYP1A1 TAS Homo sapiens 27432 R-HSA-1989765 https://reactome.org/PathwayBrowser/#/R-HSA-1989765 Expression of ABCA1 TAS Homo sapiens 27432 R-HSA-1989767 https://reactome.org/PathwayBrowser/#/R-HSA-1989767 Expression of TRIB3 TAS Homo sapiens 27432 R-HSA-1989768 https://reactome.org/PathwayBrowser/#/R-HSA-1989768 Expression of TIAM2 TAS Homo sapiens 27432 R-HSA-1989770 https://reactome.org/PathwayBrowser/#/R-HSA-1989770 Expression of PLIN2 TAS Homo sapiens 27432 R-HSA-1989771 https://reactome.org/PathwayBrowser/#/R-HSA-1989771 Expression of TNFRSF21 TAS Homo sapiens 27432 R-HSA-1989772 https://reactome.org/PathwayBrowser/#/R-HSA-1989772 Expression of GLIPR1 TAS Homo sapiens 27432 R-HSA-1989773 https://reactome.org/PathwayBrowser/#/R-HSA-1989773 Expression of CPT2 TAS Homo sapiens 27432 R-HSA-1989774 https://reactome.org/PathwayBrowser/#/R-HSA-1989774 Expression of AGT TAS Homo sapiens 27432 R-HSA-1989775 https://reactome.org/PathwayBrowser/#/R-HSA-1989775 Expression of SULT2A1 TAS Homo sapiens 27432 R-HSA-1989776 https://reactome.org/PathwayBrowser/#/R-HSA-1989776 Expression of APOA2 TAS Homo sapiens 27432 R-HSA-1989777 https://reactome.org/PathwayBrowser/#/R-HSA-1989777 Expression of RGL1 TAS Homo sapiens 27432 R-HSA-1989778 https://reactome.org/PathwayBrowser/#/R-HSA-1989778 Expression of ACSL1 TAS Homo sapiens 27432 R-HSA-1989779 https://reactome.org/PathwayBrowser/#/R-HSA-1989779 Expression of ANKRD1 TAS Homo sapiens 27432 R-HSA-2046085 https://reactome.org/PathwayBrowser/#/R-HSA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA TAS Homo sapiens 27432 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 27432 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 27432 R-HSA-400143 https://reactome.org/PathwayBrowser/#/R-HSA-400143 Fatty acid ligands activate PPARA TAS Homo sapiens 27432 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 27432 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 27432 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 27432 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 27432 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 27432 R-HSA-879724 https://reactome.org/PathwayBrowser/#/R-HSA-879724 Expression of PPARA IEA Homo sapiens 27432 R-MMU-2046085 https://reactome.org/PathwayBrowser/#/R-MMU-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Mus musculus 27432 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 27432 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 27432 R-MMU-400143 https://reactome.org/PathwayBrowser/#/R-MMU-400143 Fatty acid ligands activate PPARA IEA Mus musculus 27432 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 27432 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 27432 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 27432 R-PFA-2046085 https://reactome.org/PathwayBrowser/#/R-PFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Plasmodium falciparum 27432 R-RNO-2046085 https://reactome.org/PathwayBrowser/#/R-RNO-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Rattus norvegicus 27432 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 27432 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 27432 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus 27432 R-SSC-2046085 https://reactome.org/PathwayBrowser/#/R-SSC-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Sus scrofa 27432 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 27432 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 27432 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 27432 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 27432 R-XTR-2046085 https://reactome.org/PathwayBrowser/#/R-XTR-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Xenopus tropicalis 27432 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 27438 R-BTA-4084976 https://reactome.org/PathwayBrowser/#/R-BTA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Bos taurus 27438 R-BTA-4084989 https://reactome.org/PathwayBrowser/#/R-BTA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Bos taurus 27438 R-CFA-4084976 https://reactome.org/PathwayBrowser/#/R-CFA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Canis familiaris 27438 R-CFA-4084989 https://reactome.org/PathwayBrowser/#/R-CFA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Canis familiaris 27438 R-DME-4084976 https://reactome.org/PathwayBrowser/#/R-DME-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Drosophila melanogaster 27438 R-DME-4084989 https://reactome.org/PathwayBrowser/#/R-DME-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Drosophila melanogaster 27438 R-DRE-4084976 https://reactome.org/PathwayBrowser/#/R-DRE-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Danio rerio 27438 R-DRE-4084989 https://reactome.org/PathwayBrowser/#/R-DRE-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Danio rerio 27438 R-GGA-4084976 https://reactome.org/PathwayBrowser/#/R-GGA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Gallus gallus 27438 R-GGA-4084989 https://reactome.org/PathwayBrowser/#/R-GGA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Gallus gallus 27438 R-HSA-4084976 https://reactome.org/PathwayBrowser/#/R-HSA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P TAS Homo sapiens 27438 R-HSA-4084989 https://reactome.org/PathwayBrowser/#/R-HSA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac TAS Homo sapiens 27438 R-MMU-4084976 https://reactome.org/PathwayBrowser/#/R-MMU-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Mus musculus 27438 R-MMU-4084989 https://reactome.org/PathwayBrowser/#/R-MMU-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Mus musculus 27438 R-RNO-4084976 https://reactome.org/PathwayBrowser/#/R-RNO-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Rattus norvegicus 27438 R-RNO-4084989 https://reactome.org/PathwayBrowser/#/R-RNO-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Rattus norvegicus 27438 R-SSC-4084976 https://reactome.org/PathwayBrowser/#/R-SSC-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Sus scrofa 27438 R-SSC-4084989 https://reactome.org/PathwayBrowser/#/R-SSC-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Sus scrofa 27438 R-XTR-4084976 https://reactome.org/PathwayBrowser/#/R-XTR-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Xenopus tropicalis 27438 R-XTR-4084989 https://reactome.org/PathwayBrowser/#/R-XTR-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Xenopus tropicalis 27458 R-BTA-193727 https://reactome.org/PathwayBrowser/#/R-BTA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 27458 R-BTA-193763 https://reactome.org/PathwayBrowser/#/R-BTA-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Bos taurus 27458 R-BTA-193766 https://reactome.org/PathwayBrowser/#/R-BTA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 27458 R-CEL-193727 https://reactome.org/PathwayBrowser/#/R-CEL-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 27458 R-CEL-193763 https://reactome.org/PathwayBrowser/#/R-CEL-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Caenorhabditis elegans 27458 R-CEL-193766 https://reactome.org/PathwayBrowser/#/R-CEL-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 27458 R-CFA-193727 https://reactome.org/PathwayBrowser/#/R-CFA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 27458 R-CFA-193766 https://reactome.org/PathwayBrowser/#/R-CFA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 27458 R-DME-193727 https://reactome.org/PathwayBrowser/#/R-DME-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 27458 R-DME-193763 https://reactome.org/PathwayBrowser/#/R-DME-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Drosophila melanogaster 27458 R-DME-193766 https://reactome.org/PathwayBrowser/#/R-DME-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 27458 R-DRE-193763 https://reactome.org/PathwayBrowser/#/R-DRE-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Danio rerio 27458 R-DRE-193766 https://reactome.org/PathwayBrowser/#/R-DRE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 27458 R-GGA-193727 https://reactome.org/PathwayBrowser/#/R-GGA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 27458 R-GGA-193763 https://reactome.org/PathwayBrowser/#/R-GGA-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Gallus gallus 27458 R-GGA-193766 https://reactome.org/PathwayBrowser/#/R-GGA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 27458 R-HSA-193727 https://reactome.org/PathwayBrowser/#/R-HSA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 27458 R-HSA-193761 https://reactome.org/PathwayBrowser/#/R-HSA-193761 25(R) TetraHCA-CoA is translocated from the cytosol to the peroxisome TAS Homo sapiens 27458 R-HSA-193763 https://reactome.org/PathwayBrowser/#/R-HSA-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA TAS Homo sapiens 27458 R-HSA-193766 https://reactome.org/PathwayBrowser/#/R-HSA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 27458 R-MMU-193727 https://reactome.org/PathwayBrowser/#/R-MMU-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 27458 R-MMU-193763 https://reactome.org/PathwayBrowser/#/R-MMU-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Mus musculus 27458 R-MMU-193766 https://reactome.org/PathwayBrowser/#/R-MMU-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 27458 R-RNO-193727 https://reactome.org/PathwayBrowser/#/R-RNO-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 27458 R-RNO-193763 https://reactome.org/PathwayBrowser/#/R-RNO-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Rattus norvegicus 27458 R-RNO-193766 https://reactome.org/PathwayBrowser/#/R-RNO-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 27458 R-SCE-193727 https://reactome.org/PathwayBrowser/#/R-SCE-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 27458 R-SCE-193766 https://reactome.org/PathwayBrowser/#/R-SCE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 27458 R-SSC-193727 https://reactome.org/PathwayBrowser/#/R-SSC-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 27458 R-SSC-193766 https://reactome.org/PathwayBrowser/#/R-SSC-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 27458 R-XTR-193727 https://reactome.org/PathwayBrowser/#/R-XTR-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 27458 R-XTR-193763 https://reactome.org/PathwayBrowser/#/R-XTR-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Xenopus tropicalis 27458 R-XTR-193766 https://reactome.org/PathwayBrowser/#/R-XTR-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 27459 R-BTA-6803761 https://reactome.org/PathwayBrowser/#/R-BTA-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Bos taurus 27459 R-BTA-6803771 https://reactome.org/PathwayBrowser/#/R-BTA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Bos taurus 27459 R-CEL-6803771 https://reactome.org/PathwayBrowser/#/R-CEL-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Caenorhabditis elegans 27459 R-CFA-6803771 https://reactome.org/PathwayBrowser/#/R-CFA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Canis familiaris 27459 R-DME-6803771 https://reactome.org/PathwayBrowser/#/R-DME-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Drosophila melanogaster 27459 R-GGA-6803771 https://reactome.org/PathwayBrowser/#/R-GGA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Gallus gallus 27459 R-HSA-6803761 https://reactome.org/PathwayBrowser/#/R-HSA-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc TAS Homo sapiens 27459 R-HSA-6803771 https://reactome.org/PathwayBrowser/#/R-HSA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P TAS Homo sapiens 27459 R-MMU-6803761 https://reactome.org/PathwayBrowser/#/R-MMU-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Mus musculus 27459 R-MMU-6803771 https://reactome.org/PathwayBrowser/#/R-MMU-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Mus musculus 27459 R-RNO-6803761 https://reactome.org/PathwayBrowser/#/R-RNO-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Rattus norvegicus 27459 R-RNO-6803771 https://reactome.org/PathwayBrowser/#/R-RNO-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Rattus norvegicus 27459 R-SSC-6803761 https://reactome.org/PathwayBrowser/#/R-SSC-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Sus scrofa 27459 R-SSC-6803771 https://reactome.org/PathwayBrowser/#/R-SSC-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Sus scrofa 27459 R-XTR-6803761 https://reactome.org/PathwayBrowser/#/R-XTR-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Xenopus tropicalis 27466 R-BTA-77277 https://reactome.org/PathwayBrowser/#/R-BTA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Bos taurus 27466 R-BTA-77283 https://reactome.org/PathwayBrowser/#/R-BTA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Bos taurus 27466 R-CEL-77277 https://reactome.org/PathwayBrowser/#/R-CEL-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Caenorhabditis elegans 27466 R-CEL-77283 https://reactome.org/PathwayBrowser/#/R-CEL-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 27466 R-CFA-77277 https://reactome.org/PathwayBrowser/#/R-CFA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Canis familiaris 27466 R-CFA-77283 https://reactome.org/PathwayBrowser/#/R-CFA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Canis familiaris 27466 R-DME-77277 https://reactome.org/PathwayBrowser/#/R-DME-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Drosophila melanogaster 27466 R-DME-77283 https://reactome.org/PathwayBrowser/#/R-DME-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Drosophila melanogaster 27466 R-DRE-77277 https://reactome.org/PathwayBrowser/#/R-DRE-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Danio rerio 27466 R-DRE-77283 https://reactome.org/PathwayBrowser/#/R-DRE-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Danio rerio 27466 R-GGA-77277 https://reactome.org/PathwayBrowser/#/R-GGA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Gallus gallus 27466 R-GGA-77283 https://reactome.org/PathwayBrowser/#/R-GGA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Gallus gallus 27466 R-HSA-77277 https://reactome.org/PathwayBrowser/#/R-HSA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA TAS Homo sapiens 27466 R-HSA-77283 https://reactome.org/PathwayBrowser/#/R-HSA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H TAS Homo sapiens 27466 R-MMU-77277 https://reactome.org/PathwayBrowser/#/R-MMU-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Mus musculus 27466 R-MMU-77283 https://reactome.org/PathwayBrowser/#/R-MMU-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Mus musculus 27466 R-RNO-77277 https://reactome.org/PathwayBrowser/#/R-RNO-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Rattus norvegicus 27466 R-RNO-77283 https://reactome.org/PathwayBrowser/#/R-RNO-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Rattus norvegicus 27466 R-SSC-77277 https://reactome.org/PathwayBrowser/#/R-SSC-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Sus scrofa 27466 R-SSC-77283 https://reactome.org/PathwayBrowser/#/R-SSC-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Sus scrofa 27466 R-XTR-77277 https://reactome.org/PathwayBrowser/#/R-XTR-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Xenopus tropicalis 27466 R-XTR-77283 https://reactome.org/PathwayBrowser/#/R-XTR-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Xenopus tropicalis 27468 R-BTA-73616 https://reactome.org/PathwayBrowser/#/R-BTA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Bos taurus 27468 R-BTA-73618 https://reactome.org/PathwayBrowser/#/R-BTA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Bos taurus 27468 R-CEL-73616 https://reactome.org/PathwayBrowser/#/R-CEL-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Caenorhabditis elegans 27468 R-CEL-73618 https://reactome.org/PathwayBrowser/#/R-CEL-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Caenorhabditis elegans 27468 R-CFA-73616 https://reactome.org/PathwayBrowser/#/R-CFA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Canis familiaris 27468 R-CFA-73618 https://reactome.org/PathwayBrowser/#/R-CFA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Canis familiaris 27468 R-DDI-73616 https://reactome.org/PathwayBrowser/#/R-DDI-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Dictyostelium discoideum 27468 R-DDI-73618 https://reactome.org/PathwayBrowser/#/R-DDI-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Dictyostelium discoideum 27468 R-DME-73616 https://reactome.org/PathwayBrowser/#/R-DME-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Drosophila melanogaster 27468 R-DME-73618 https://reactome.org/PathwayBrowser/#/R-DME-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Drosophila melanogaster 27468 R-DRE-73616 https://reactome.org/PathwayBrowser/#/R-DRE-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Danio rerio 27468 R-DRE-73618 https://reactome.org/PathwayBrowser/#/R-DRE-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Danio rerio 27468 R-GGA-73616 https://reactome.org/PathwayBrowser/#/R-GGA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Gallus gallus 27468 R-GGA-73618 https://reactome.org/PathwayBrowser/#/R-GGA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Gallus gallus 27468 R-HSA-73616 https://reactome.org/PathwayBrowser/#/R-HSA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ TAS Homo sapiens 27468 R-HSA-73618 https://reactome.org/PathwayBrowser/#/R-HSA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate TAS Homo sapiens 27468 R-MMU-73616 https://reactome.org/PathwayBrowser/#/R-MMU-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Mus musculus 27468 R-MMU-73618 https://reactome.org/PathwayBrowser/#/R-MMU-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Mus musculus 27468 R-RNO-73616 https://reactome.org/PathwayBrowser/#/R-RNO-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Rattus norvegicus 27468 R-RNO-73618 https://reactome.org/PathwayBrowser/#/R-RNO-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Rattus norvegicus 27468 R-SSC-73616 https://reactome.org/PathwayBrowser/#/R-SSC-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Sus scrofa 27468 R-SSC-73618 https://reactome.org/PathwayBrowser/#/R-SSC-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Sus scrofa 27468 R-XTR-73616 https://reactome.org/PathwayBrowser/#/R-XTR-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Xenopus tropicalis 27470 R-BTA-197963 https://reactome.org/PathwayBrowser/#/R-BTA-197963 DHFR2 reduces FOLA to DHF IEA Bos taurus 27470 R-BTA-200646 https://reactome.org/PathwayBrowser/#/R-BTA-200646 Cytosolic folate export across the plasma membrane IEA Bos taurus 27470 R-BTA-200729 https://reactome.org/PathwayBrowser/#/R-BTA-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Bos taurus 27470 R-BTA-8940134 https://reactome.org/PathwayBrowser/#/R-BTA-8940134 FOLR2 binds FOLA IEA Bos taurus 27470 R-BTA-8942344 https://reactome.org/PathwayBrowser/#/R-BTA-8942344 FOLR2 transports FOLA from extracellular region to cytosol IEA Bos taurus 27470 R-BTA-9709098 https://reactome.org/PathwayBrowser/#/R-BTA-9709098 DHFR dimer reduces FOLA to DHF IEA Bos taurus 27470 R-CEL-197963 https://reactome.org/PathwayBrowser/#/R-CEL-197963 DHFR2 reduces FOLA to DHF IEA Caenorhabditis elegans 27470 R-CEL-200646 https://reactome.org/PathwayBrowser/#/R-CEL-200646 Cytosolic folate export across the plasma membrane IEA Caenorhabditis elegans 27470 R-CEL-200729 https://reactome.org/PathwayBrowser/#/R-CEL-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Caenorhabditis elegans 27470 R-CEL-9709098 https://reactome.org/PathwayBrowser/#/R-CEL-9709098 DHFR dimer reduces FOLA to DHF IEA Caenorhabditis elegans 27470 R-CFA-197963 https://reactome.org/PathwayBrowser/#/R-CFA-197963 DHFR2 reduces FOLA to DHF IEA Canis familiaris 27470 R-CFA-200646 https://reactome.org/PathwayBrowser/#/R-CFA-200646 Cytosolic folate export across the plasma membrane IEA Canis familiaris 27470 R-CFA-200729 https://reactome.org/PathwayBrowser/#/R-CFA-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Canis familiaris 27470 R-CFA-8940134 https://reactome.org/PathwayBrowser/#/R-CFA-8940134 FOLR2 binds FOLA IEA Canis familiaris 27470 R-CFA-8942344 https://reactome.org/PathwayBrowser/#/R-CFA-8942344 FOLR2 transports FOLA from extracellular region to cytosol IEA Canis familiaris 27470 R-CFA-9709098 https://reactome.org/PathwayBrowser/#/R-CFA-9709098 DHFR dimer reduces FOLA to DHF IEA Canis familiaris 27470 R-DDI-197963 https://reactome.org/PathwayBrowser/#/R-DDI-197963 DHFR2 reduces FOLA to DHF IEA Dictyostelium discoideum 27470 R-DDI-9709098 https://reactome.org/PathwayBrowser/#/R-DDI-9709098 DHFR dimer reduces FOLA to DHF IEA Dictyostelium discoideum 27470 R-DME-197963 https://reactome.org/PathwayBrowser/#/R-DME-197963 DHFR2 reduces FOLA to DHF IEA Drosophila melanogaster 27470 R-DME-200646 https://reactome.org/PathwayBrowser/#/R-DME-200646 Cytosolic folate export across the plasma membrane IEA Drosophila melanogaster 27470 R-DME-200729 https://reactome.org/PathwayBrowser/#/R-DME-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Drosophila melanogaster 27470 R-DME-9709098 https://reactome.org/PathwayBrowser/#/R-DME-9709098 DHFR dimer reduces FOLA to DHF IEA Drosophila melanogaster 27470 R-DRE-197963 https://reactome.org/PathwayBrowser/#/R-DRE-197963 DHFR2 reduces FOLA to DHF IEA Danio rerio 27470 R-DRE-200646 https://reactome.org/PathwayBrowser/#/R-DRE-200646 Cytosolic folate export across the plasma membrane IEA Danio rerio 27470 R-DRE-200729 https://reactome.org/PathwayBrowser/#/R-DRE-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Danio rerio 27470 R-DRE-8940134 https://reactome.org/PathwayBrowser/#/R-DRE-8940134 FOLR2 binds FOLA IEA Danio rerio 27470 R-DRE-8942344 https://reactome.org/PathwayBrowser/#/R-DRE-8942344 FOLR2 transports FOLA from extracellular region to cytosol IEA Danio rerio 27470 R-DRE-9709098 https://reactome.org/PathwayBrowser/#/R-DRE-9709098 DHFR dimer reduces FOLA to DHF IEA Danio rerio 27470 R-GGA-197963 https://reactome.org/PathwayBrowser/#/R-GGA-197963 DHFR2 reduces FOLA to DHF IEA Gallus gallus 27470 R-GGA-200646 https://reactome.org/PathwayBrowser/#/R-GGA-200646 Cytosolic folate export across the plasma membrane IEA Gallus gallus 27470 R-GGA-200729 https://reactome.org/PathwayBrowser/#/R-GGA-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Gallus gallus 27470 R-GGA-8940134 https://reactome.org/PathwayBrowser/#/R-GGA-8940134 FOLR2 binds FOLA IEA Gallus gallus 27470 R-GGA-8942344 https://reactome.org/PathwayBrowser/#/R-GGA-8942344 FOLR2 transports FOLA from extracellular region to cytosol IEA Gallus gallus 27470 R-GGA-9709098 https://reactome.org/PathwayBrowser/#/R-GGA-9709098 DHFR dimer reduces FOLA to DHF IEA Gallus gallus 27470 R-HSA-197963 https://reactome.org/PathwayBrowser/#/R-HSA-197963 DHFR2 reduces FOLA to DHF TAS Homo sapiens 27470 R-HSA-200646 https://reactome.org/PathwayBrowser/#/R-HSA-200646 Cytosolic folate export across the plasma membrane TAS Homo sapiens 27470 R-HSA-200729 https://reactome.org/PathwayBrowser/#/R-HSA-200729 SLC46A1 transports FOLA from extracellular region to cytosol TAS Homo sapiens 27470 R-HSA-8940134 https://reactome.org/PathwayBrowser/#/R-HSA-8940134 FOLR2 binds FOLA TAS Homo sapiens 27470 R-HSA-8942344 https://reactome.org/PathwayBrowser/#/R-HSA-8942344 FOLR2 transports FOLA from extracellular region to cytosol TAS Homo sapiens 27470 R-HSA-9709098 https://reactome.org/PathwayBrowser/#/R-HSA-9709098 DHFR dimer reduces FOLA to DHF TAS Homo sapiens 27470 R-MMU-197963 https://reactome.org/PathwayBrowser/#/R-MMU-197963 DHFR2 reduces FOLA to DHF IEA Mus musculus 27470 R-MMU-200646 https://reactome.org/PathwayBrowser/#/R-MMU-200646 Cytosolic folate export across the plasma membrane IEA Mus musculus 27470 R-MMU-200729 https://reactome.org/PathwayBrowser/#/R-MMU-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Mus musculus 27470 R-MMU-8940134 https://reactome.org/PathwayBrowser/#/R-MMU-8940134 FOLR2 binds FOLA IEA Mus musculus 27470 R-MMU-8942344 https://reactome.org/PathwayBrowser/#/R-MMU-8942344 FOLR2 transports FOLA from extracellular region to cytosol IEA Mus musculus 27470 R-MMU-9709098 https://reactome.org/PathwayBrowser/#/R-MMU-9709098 DHFR dimer reduces FOLA to DHF IEA Mus musculus 27470 R-RNO-197963 https://reactome.org/PathwayBrowser/#/R-RNO-197963 DHFR2 reduces FOLA to DHF IEA Rattus norvegicus 27470 R-RNO-200646 https://reactome.org/PathwayBrowser/#/R-RNO-200646 Cytosolic folate export across the plasma membrane IEA Rattus norvegicus 27470 R-RNO-200729 https://reactome.org/PathwayBrowser/#/R-RNO-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Rattus norvegicus 27470 R-RNO-8940134 https://reactome.org/PathwayBrowser/#/R-RNO-8940134 FOLR2 binds FOLA IEA Rattus norvegicus 27470 R-RNO-8942344 https://reactome.org/PathwayBrowser/#/R-RNO-8942344 FOLR2 transports FOLA from extracellular region to cytosol IEA Rattus norvegicus 27470 R-RNO-9709098 https://reactome.org/PathwayBrowser/#/R-RNO-9709098 DHFR dimer reduces FOLA to DHF IEA Rattus norvegicus 27470 R-SCE-197963 https://reactome.org/PathwayBrowser/#/R-SCE-197963 DHFR2 reduces FOLA to DHF IEA Saccharomyces cerevisiae 27470 R-SCE-200646 https://reactome.org/PathwayBrowser/#/R-SCE-200646 Cytosolic folate export across the plasma membrane IEA Saccharomyces cerevisiae 27470 R-SCE-200729 https://reactome.org/PathwayBrowser/#/R-SCE-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Saccharomyces cerevisiae 27470 R-SCE-9709098 https://reactome.org/PathwayBrowser/#/R-SCE-9709098 DHFR dimer reduces FOLA to DHF IEA Saccharomyces cerevisiae 27470 R-SPO-197963 https://reactome.org/PathwayBrowser/#/R-SPO-197963 DHFR2 reduces FOLA to DHF IEA Schizosaccharomyces pombe 27470 R-SPO-200646 https://reactome.org/PathwayBrowser/#/R-SPO-200646 Cytosolic folate export across the plasma membrane IEA Schizosaccharomyces pombe 27470 R-SPO-200729 https://reactome.org/PathwayBrowser/#/R-SPO-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Schizosaccharomyces pombe 27470 R-SPO-9709098 https://reactome.org/PathwayBrowser/#/R-SPO-9709098 DHFR dimer reduces FOLA to DHF IEA Schizosaccharomyces pombe 27470 R-SSC-197963 https://reactome.org/PathwayBrowser/#/R-SSC-197963 DHFR2 reduces FOLA to DHF IEA Sus scrofa 27470 R-SSC-200646 https://reactome.org/PathwayBrowser/#/R-SSC-200646 Cytosolic folate export across the plasma membrane IEA Sus scrofa 27470 R-SSC-200729 https://reactome.org/PathwayBrowser/#/R-SSC-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Sus scrofa 27470 R-SSC-8940134 https://reactome.org/PathwayBrowser/#/R-SSC-8940134 FOLR2 binds FOLA IEA Sus scrofa 27470 R-SSC-8942344 https://reactome.org/PathwayBrowser/#/R-SSC-8942344 FOLR2 transports FOLA from extracellular region to cytosol IEA Sus scrofa 27470 R-SSC-9709098 https://reactome.org/PathwayBrowser/#/R-SSC-9709098 DHFR dimer reduces FOLA to DHF IEA Sus scrofa 27470 R-XTR-200646 https://reactome.org/PathwayBrowser/#/R-XTR-200646 Cytosolic folate export across the plasma membrane IEA Xenopus tropicalis 27470 R-XTR-200729 https://reactome.org/PathwayBrowser/#/R-XTR-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Xenopus tropicalis 27485 R-HSA-2161563 https://reactome.org/PathwayBrowser/#/R-HSA-2161563 PGJ2 is isomerised to delta12-PGJ2 TAS Homo sapiens 27485 R-HSA-2161733 https://reactome.org/PathwayBrowser/#/R-HSA-2161733 PGD2 is dehydrated to PGJ2 TAS Homo sapiens 27505 R-BTA-192331 https://reactome.org/PathwayBrowser/#/R-BTA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Bos taurus 27505 R-BTA-192335 https://reactome.org/PathwayBrowser/#/R-BTA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Bos taurus 27505 R-CEL-192331 https://reactome.org/PathwayBrowser/#/R-CEL-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Caenorhabditis elegans 27505 R-CEL-192335 https://reactome.org/PathwayBrowser/#/R-CEL-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Caenorhabditis elegans 27505 R-CFA-192331 https://reactome.org/PathwayBrowser/#/R-CFA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Canis familiaris 27505 R-CFA-192335 https://reactome.org/PathwayBrowser/#/R-CFA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Canis familiaris 27505 R-DDI-192331 https://reactome.org/PathwayBrowser/#/R-DDI-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Dictyostelium discoideum 27505 R-DDI-192335 https://reactome.org/PathwayBrowser/#/R-DDI-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Dictyostelium discoideum 27505 R-DME-192331 https://reactome.org/PathwayBrowser/#/R-DME-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Drosophila melanogaster 27505 R-DME-192335 https://reactome.org/PathwayBrowser/#/R-DME-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Drosophila melanogaster 27505 R-GGA-192331 https://reactome.org/PathwayBrowser/#/R-GGA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Gallus gallus 27505 R-GGA-192335 https://reactome.org/PathwayBrowser/#/R-GGA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Gallus gallus 27505 R-HSA-192331 https://reactome.org/PathwayBrowser/#/R-HSA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA TAS Homo sapiens 27505 R-HSA-192335 https://reactome.org/PathwayBrowser/#/R-HSA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) TAS Homo sapiens 27505 R-MMU-192331 https://reactome.org/PathwayBrowser/#/R-MMU-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Mus musculus 27505 R-MMU-192335 https://reactome.org/PathwayBrowser/#/R-MMU-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Mus musculus 27505 R-RNO-192331 https://reactome.org/PathwayBrowser/#/R-RNO-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Rattus norvegicus 27505 R-RNO-192335 https://reactome.org/PathwayBrowser/#/R-RNO-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Rattus norvegicus 27505 R-SSC-192335 https://reactome.org/PathwayBrowser/#/R-SSC-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Sus scrofa 27505 R-XTR-192335 https://reactome.org/PathwayBrowser/#/R-XTR-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Xenopus tropicalis 27510 R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 27510 R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 27510 R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 27510 R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 27510 R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 27510 R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 27510 R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 27510 R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 27510 R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 27510 R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 27510 R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 27510 R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 27510 R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 27510 R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 27510 R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 27510 R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 27510 R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 27510 R-RNO-76453 https://reactome.org/PathwayBrowser/#/R-RNO-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Rattus norvegicus 27510 R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa 27510 R-SSC-76453 https://reactome.org/PathwayBrowser/#/R-SSC-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Sus scrofa 27510 R-XTR-211881 https://reactome.org/PathwayBrowser/#/R-XTR-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Xenopus tropicalis 27510 R-XTR-76453 https://reactome.org/PathwayBrowser/#/R-XTR-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Xenopus tropicalis 27537 R-BTA-6809808 https://reactome.org/PathwayBrowser/#/R-BTA-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Bos taurus 27537 R-BTA-77333 https://reactome.org/PathwayBrowser/#/R-BTA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Bos taurus 27537 R-BTA-77338 https://reactome.org/PathwayBrowser/#/R-BTA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Bos taurus 27537 R-CEL-6809808 https://reactome.org/PathwayBrowser/#/R-CEL-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Caenorhabditis elegans 27537 R-CEL-77333 https://reactome.org/PathwayBrowser/#/R-CEL-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Caenorhabditis elegans 27537 R-CEL-77338 https://reactome.org/PathwayBrowser/#/R-CEL-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 27537 R-CFA-6809808 https://reactome.org/PathwayBrowser/#/R-CFA-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Canis familiaris 27537 R-CFA-77333 https://reactome.org/PathwayBrowser/#/R-CFA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Canis familiaris 27537 R-CFA-77338 https://reactome.org/PathwayBrowser/#/R-CFA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Canis familiaris 27537 R-DDI-77333 https://reactome.org/PathwayBrowser/#/R-DDI-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Dictyostelium discoideum 27537 R-DME-6809808 https://reactome.org/PathwayBrowser/#/R-DME-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Drosophila melanogaster 27537 R-DME-77333 https://reactome.org/PathwayBrowser/#/R-DME-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Drosophila melanogaster 27537 R-DME-77338 https://reactome.org/PathwayBrowser/#/R-DME-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 27537 R-GGA-6809808 https://reactome.org/PathwayBrowser/#/R-GGA-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Gallus gallus 27537 R-GGA-77338 https://reactome.org/PathwayBrowser/#/R-GGA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Gallus gallus 27537 R-HSA-6809808 https://reactome.org/PathwayBrowser/#/R-HSA-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA TAS Homo sapiens 27537 R-HSA-77333 https://reactome.org/PathwayBrowser/#/R-HSA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA TAS Homo sapiens 27537 R-HSA-77338 https://reactome.org/PathwayBrowser/#/R-HSA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 TAS Homo sapiens 27537 R-MMU-6809808 https://reactome.org/PathwayBrowser/#/R-MMU-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Mus musculus 27537 R-MMU-77333 https://reactome.org/PathwayBrowser/#/R-MMU-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Mus musculus 27537 R-MMU-77338 https://reactome.org/PathwayBrowser/#/R-MMU-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Mus musculus 27537 R-RNO-6809808 https://reactome.org/PathwayBrowser/#/R-RNO-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Rattus norvegicus 27537 R-RNO-77333 https://reactome.org/PathwayBrowser/#/R-RNO-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Rattus norvegicus 27537 R-RNO-77338 https://reactome.org/PathwayBrowser/#/R-RNO-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 27537 R-SCE-6809808 https://reactome.org/PathwayBrowser/#/R-SCE-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Saccharomyces cerevisiae 27537 R-SSC-6809808 https://reactome.org/PathwayBrowser/#/R-SSC-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Sus scrofa 27537 R-SSC-77333 https://reactome.org/PathwayBrowser/#/R-SSC-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Sus scrofa 27537 R-SSC-77338 https://reactome.org/PathwayBrowser/#/R-SSC-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Sus scrofa 27537 R-XTR-6809808 https://reactome.org/PathwayBrowser/#/R-XTR-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Xenopus tropicalis 27537 R-XTR-77333 https://reactome.org/PathwayBrowser/#/R-XTR-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Xenopus tropicalis 27551 R-BTA-212269 https://reactome.org/PathwayBrowser/#/R-BTA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Bos taurus 27551 R-BTA-427337 https://reactome.org/PathwayBrowser/#/R-BTA-427337 MBD2 binds methylcytosine in chromatin IEA Bos taurus 27551 R-BTA-73718 https://reactome.org/PathwayBrowser/#/R-BTA-73718 UBF-1 Binds rDNA Promoter IEA Bos taurus 27551 R-CFA-212269 https://reactome.org/PathwayBrowser/#/R-CFA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Canis familiaris 27551 R-CFA-427337 https://reactome.org/PathwayBrowser/#/R-CFA-427337 MBD2 binds methylcytosine in chromatin IEA Canis familiaris 27551 R-CFA-73718 https://reactome.org/PathwayBrowser/#/R-CFA-73718 UBF-1 Binds rDNA Promoter IEA Canis familiaris 27551 R-DME-212269 https://reactome.org/PathwayBrowser/#/R-DME-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Drosophila melanogaster 27551 R-DME-427337 https://reactome.org/PathwayBrowser/#/R-DME-427337 MBD2 binds methylcytosine in chromatin IEA Drosophila melanogaster 27551 R-DRE-212269 https://reactome.org/PathwayBrowser/#/R-DRE-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Danio rerio 27551 R-DRE-427337 https://reactome.org/PathwayBrowser/#/R-DRE-427337 MBD2 binds methylcytosine in chromatin IEA Danio rerio 27551 R-DRE-73718 https://reactome.org/PathwayBrowser/#/R-DRE-73718 UBF-1 Binds rDNA Promoter IEA Danio rerio 27551 R-GGA-212269 https://reactome.org/PathwayBrowser/#/R-GGA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Gallus gallus 27551 R-GGA-73718 https://reactome.org/PathwayBrowser/#/R-GGA-73718 UBF-1 Binds rDNA Promoter IEA Gallus gallus 27551 R-HSA-212269 https://reactome.org/PathwayBrowser/#/R-HSA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 TAS Homo sapiens 27551 R-HSA-427337 https://reactome.org/PathwayBrowser/#/R-HSA-427337 MBD2 binds methylcytosine in chromatin TAS Homo sapiens 27551 R-HSA-5221014 https://reactome.org/PathwayBrowser/#/R-HSA-5221014 TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine IEA Homo sapiens 27551 R-HSA-5227490 https://reactome.org/PathwayBrowser/#/R-HSA-5227490 NoRC:HDAC:DNMT methylates cytosine of the rRNA genes IEA Homo sapiens 27551 R-HSA-5334097 https://reactome.org/PathwayBrowser/#/R-HSA-5334097 DNMT3B:DNMT3L methylates cytosine in DNA IEA Homo sapiens 27551 R-HSA-5334099 https://reactome.org/PathwayBrowser/#/R-HSA-5334099 UHRF1 binds chromatin with hemimethylated cytosine IEA Homo sapiens 27551 R-HSA-5334151 https://reactome.org/PathwayBrowser/#/R-HSA-5334151 DNMT1 methylates cytosine in hemimethylated DNA IEA Homo sapiens 27551 R-HSA-5334152 https://reactome.org/PathwayBrowser/#/R-HSA-5334152 DNMT3A:DNMT3L methylates cytosine in DNA IEA Homo sapiens 27551 R-HSA-5334160 https://reactome.org/PathwayBrowser/#/R-HSA-5334160 UHRF1:Chromatin binds DNMT1 IEA Homo sapiens 27551 R-HSA-73718 https://reactome.org/PathwayBrowser/#/R-HSA-73718 UBF-1 Binds rDNA Promoter TAS Homo sapiens 27551 R-HSA-9817458 https://reactome.org/PathwayBrowser/#/R-HSA-9817458 TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 IEA Homo sapiens 27551 R-HSA-9817471 https://reactome.org/PathwayBrowser/#/R-HSA-9817471 DPPA3 binds histone H3K9me2 in chromatin IEA Homo sapiens 27551 R-HSA-9817512 https://reactome.org/PathwayBrowser/#/R-HSA-9817512 UNG (UNG2) and base excision repair remove uridine and 5-methylcytidine from chromatin containing histone H3.3 IEA Homo sapiens 27551 R-HSA-9817513 https://reactome.org/PathwayBrowser/#/R-HSA-9817513 AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine IEA Homo sapiens 27551 R-HSA-9822591 https://reactome.org/PathwayBrowser/#/R-HSA-9822591 TET3 binds chromatin with H3K17me2a and 5-mC:METTL23:STGP4 IEA Homo sapiens 27551 R-HSA-9822597 https://reactome.org/PathwayBrowser/#/R-HSA-9822597 METTL23 and STGP4 (GSE) bind H3.3 dimethylarginine-17 (H3K17me2a) IEA Homo sapiens 27551 R-MMU-212269 https://reactome.org/PathwayBrowser/#/R-MMU-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Mus musculus 27551 R-MMU-5220944 https://reactome.org/PathwayBrowser/#/R-MMU-5220944 Tet1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine TAS Mus musculus 27551 R-MMU-5336231 https://reactome.org/PathwayBrowser/#/R-MMU-5336231 Uhrf1 binds chromatin with hemimethylC TAS Mus musculus 27551 R-MMU-5336316 https://reactome.org/PathwayBrowser/#/R-MMU-5336316 Dnmt3a:Dnmt3l methylates cytosine in DNA TAS Mus musculus 27551 R-MMU-5336365 https://reactome.org/PathwayBrowser/#/R-MMU-5336365 Uhrf1:Chromatin binds Dnmt1 TAS Mus musculus 27551 R-MMU-5336369 https://reactome.org/PathwayBrowser/#/R-MMU-5336369 Dnmt1 methylates cytosine in hemimethylated DNA TAS Mus musculus 27551 R-MMU-5336380 https://reactome.org/PathwayBrowser/#/R-MMU-5336380 Dnmt3b:Dnmt3l methylates cytosine in DNA TAS Mus musculus 27551 R-MMU-573383 https://reactome.org/PathwayBrowser/#/R-MMU-573383 NoRC:intergenic spacer:Hdac:Dnmt complex methylates cytosine in the rRNA genes TAS Mus musculus 27551 R-MMU-9817463 https://reactome.org/PathwayBrowser/#/R-MMU-9817463 Tet3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 dimethylated on lysine-9 TAS Mus musculus 27551 R-MMU-9817490 https://reactome.org/PathwayBrowser/#/R-MMU-9817490 Dppa3 binds histone H3K9me2 in chromatin TAS Mus musculus 27551 R-MMU-9817520 https://reactome.org/PathwayBrowser/#/R-MMU-9817520 Aicda deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine TAS Mus musculus 27551 R-MMU-9817522 https://reactome.org/PathwayBrowser/#/R-MMU-9817522 Ung (Ung2) and base excision repair remove uridine and 5-methylcytidine from chromatin containing histone H3.3 TAS Mus musculus 27551 R-MMU-9822631 https://reactome.org/PathwayBrowser/#/R-MMU-9822631 Tet3 binds chromatin with H3K17me2a and 5-mC:Mettl23:Stgp4 TAS Mus musculus 27551 R-MMU-9822637 https://reactome.org/PathwayBrowser/#/R-MMU-9822637 Mettl23 and Stgp4 (Gse) bind chromatin with H3.3 dimethylarginine-17 TAS Mus musculus 27551 R-RNO-212269 https://reactome.org/PathwayBrowser/#/R-RNO-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Rattus norvegicus 27551 R-RNO-427337 https://reactome.org/PathwayBrowser/#/R-RNO-427337 MBD2 binds methylcytosine in chromatin IEA Rattus norvegicus 27551 R-RNO-73718 https://reactome.org/PathwayBrowser/#/R-RNO-73718 UBF-1 Binds rDNA Promoter IEA Rattus norvegicus 27551 R-SSC-212269 https://reactome.org/PathwayBrowser/#/R-SSC-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Sus scrofa 27551 R-SSC-427337 https://reactome.org/PathwayBrowser/#/R-SSC-427337 MBD2 binds methylcytosine in chromatin IEA Sus scrofa 27551 R-SSC-73718 https://reactome.org/PathwayBrowser/#/R-SSC-73718 UBF-1 Binds rDNA Promoter IEA Sus scrofa 27551 R-XTR-212269 https://reactome.org/PathwayBrowser/#/R-XTR-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Xenopus tropicalis 27551 R-XTR-427337 https://reactome.org/PathwayBrowser/#/R-XTR-427337 MBD2 binds methylcytosine in chromatin IEA Xenopus tropicalis 27551 R-XTR-73718 https://reactome.org/PathwayBrowser/#/R-XTR-73718 UBF-1 Binds rDNA Promoter IEA Xenopus tropicalis 27555 R-HSA-2161666 https://reactome.org/PathwayBrowser/#/R-HSA-2161666 PGA2 is isomerised to PGC2 TAS Homo sapiens 27555 R-HSA-2161735 https://reactome.org/PathwayBrowser/#/R-HSA-2161735 PGC2 is isomerised to PGB2 TAS Homo sapiens 27561 R-BTA-176059 https://reactome.org/PathwayBrowser/#/R-BTA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Bos taurus 27561 R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 27561 R-CFA-176059 https://reactome.org/PathwayBrowser/#/R-CFA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Canis familiaris 27561 R-DDI-176059 https://reactome.org/PathwayBrowser/#/R-DDI-176059 GST trimers transfer GS from GSH to luminal substrates IEA Dictyostelium discoideum 27561 R-DME-176059 https://reactome.org/PathwayBrowser/#/R-DME-176059 GST trimers transfer GS from GSH to luminal substrates IEA Drosophila melanogaster 27561 R-DRE-176059 https://reactome.org/PathwayBrowser/#/R-DRE-176059 GST trimers transfer GS from GSH to luminal substrates IEA Danio rerio 27561 R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 27561 R-GGA-176059 https://reactome.org/PathwayBrowser/#/R-GGA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Gallus gallus 27561 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 27561 R-HSA-176059 https://reactome.org/PathwayBrowser/#/R-HSA-176059 GST trimers transfer GS from GSH to luminal substrates TAS Homo sapiens 27561 R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 27561 R-MMU-176059 https://reactome.org/PathwayBrowser/#/R-MMU-176059 GST trimers transfer GS from GSH to luminal substrates IEA Mus musculus 27561 R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 27561 R-RNO-176059 https://reactome.org/PathwayBrowser/#/R-RNO-176059 GST trimers transfer GS from GSH to luminal substrates IEA Rattus norvegicus 27561 R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 27561 R-SSC-176059 https://reactome.org/PathwayBrowser/#/R-SSC-176059 GST trimers transfer GS from GSH to luminal substrates IEA Sus scrofa 27561 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 27561 R-XTR-176059 https://reactome.org/PathwayBrowser/#/R-XTR-176059 GST trimers transfer GS from GSH to luminal substrates IEA Xenopus tropicalis 27562 R-BTA-2161792 https://reactome.org/PathwayBrowser/#/R-BTA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Bos taurus 27562 R-CFA-2161792 https://reactome.org/PathwayBrowser/#/R-CFA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Canis familiaris 27562 R-DRE-2161792 https://reactome.org/PathwayBrowser/#/R-DRE-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Danio rerio 27562 R-HSA-2161790 https://reactome.org/PathwayBrowser/#/R-HSA-2161790 20cooh-LTB4 is converted to 18cooh-LTB4 TAS Homo sapiens 27562 R-HSA-2161792 https://reactome.org/PathwayBrowser/#/R-HSA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 TAS Homo sapiens 27562 R-HSA-2161979 https://reactome.org/PathwayBrowser/#/R-HSA-2161979 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH TAS Homo sapiens 27562 R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus 27562 R-RNO-2161792 https://reactome.org/PathwayBrowser/#/R-RNO-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 27562 R-SSC-2161792 https://reactome.org/PathwayBrowser/#/R-SSC-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Sus scrofa 27562 R-XTR-2161792 https://reactome.org/PathwayBrowser/#/R-XTR-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 27565 R-BTA-174963 https://reactome.org/PathwayBrowser/#/R-BTA-174963 NAT1 acetylation IEA Bos taurus 27565 R-DRE-174963 https://reactome.org/PathwayBrowser/#/R-DRE-174963 NAT1 acetylation IEA Danio rerio 27565 R-GGA-174963 https://reactome.org/PathwayBrowser/#/R-GGA-174963 NAT1 acetylation IEA Gallus gallus 27565 R-HSA-174963 https://reactome.org/PathwayBrowser/#/R-HSA-174963 NAT1 acetylation TAS Homo sapiens 27565 R-MMU-174963 https://reactome.org/PathwayBrowser/#/R-MMU-174963 NAT1 acetylation IEA Mus musculus 27565 R-RNO-174963 https://reactome.org/PathwayBrowser/#/R-RNO-174963 NAT1 acetylation IEA Rattus norvegicus 27565 R-SSC-174963 https://reactome.org/PathwayBrowser/#/R-SSC-174963 NAT1 acetylation IEA Sus scrofa 27584 R-BTA-1449687 https://reactome.org/PathwayBrowser/#/R-BTA-1449687 Corticosteroids bind to CBG in blood IEA Bos taurus 27584 R-BTA-193965 https://reactome.org/PathwayBrowser/#/R-BTA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Bos taurus 27584 R-BTA-4341025 https://reactome.org/PathwayBrowser/#/R-BTA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Bos taurus 27584 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 27584 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 27584 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 27584 R-BTA-5618099 https://reactome.org/PathwayBrowser/#/R-BTA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Bos taurus 27584 R-CEL-1449687 https://reactome.org/PathwayBrowser/#/R-CEL-1449687 Corticosteroids bind to CBG in blood IEA Caenorhabditis elegans 27584 R-CFA-1449687 https://reactome.org/PathwayBrowser/#/R-CFA-1449687 Corticosteroids bind to CBG in blood IEA Canis familiaris 27584 R-CFA-193965 https://reactome.org/PathwayBrowser/#/R-CFA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Canis familiaris 27584 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 27584 R-CFA-5618099 https://reactome.org/PathwayBrowser/#/R-CFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Canis familiaris 27584 R-DME-1449687 https://reactome.org/PathwayBrowser/#/R-DME-1449687 Corticosteroids bind to CBG in blood IEA Drosophila melanogaster 27584 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 27584 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 27584 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 27584 R-DME-5618099 https://reactome.org/PathwayBrowser/#/R-DME-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 27584 R-DRE-1449687 https://reactome.org/PathwayBrowser/#/R-DRE-1449687 Corticosteroids bind to CBG in blood IEA Danio rerio 27584 R-DRE-4341025 https://reactome.org/PathwayBrowser/#/R-DRE-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Danio rerio 27584 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 27584 R-DRE-5618099 https://reactome.org/PathwayBrowser/#/R-DRE-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Danio rerio 27584 R-GGA-4341025 https://reactome.org/PathwayBrowser/#/R-GGA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Gallus gallus 27584 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 27584 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 27584 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 27584 R-GGA-5618099 https://reactome.org/PathwayBrowser/#/R-GGA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Gallus gallus 27584 R-HSA-1449687 https://reactome.org/PathwayBrowser/#/R-HSA-1449687 Corticosteroids bind to CBG in blood TAS Homo sapiens 27584 R-HSA-193965 https://reactome.org/PathwayBrowser/#/R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO TAS Homo sapiens 27584 R-HSA-4341025 https://reactome.org/PathwayBrowser/#/R-HSA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 TAS Homo sapiens 27584 R-HSA-549493 https://reactome.org/PathwayBrowser/#/R-HSA-549493 Expression of PERIOD-2 IEA Homo sapiens 27584 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 27584 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 27584 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 27584 R-HSA-5618099 https://reactome.org/PathwayBrowser/#/R-HSA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) TAS Homo sapiens 27584 R-HSA-8848804 https://reactome.org/PathwayBrowser/#/R-HSA-8848804 HIF1A,EPAS1 promote PTK6 gene expression TAS Homo sapiens 27584 R-HSA-8856930 https://reactome.org/PathwayBrowser/#/R-HSA-8856930 EPAS1 (HIF2A) and activated NR3C1 (GCR) bind PTK6 gene TAS Homo sapiens 27584 R-HSA-8939900 https://reactome.org/PathwayBrowser/#/R-HSA-8939900 RUNX2 gene expression from proximal (P2) promoter is stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and inhibited by ESRRA:PPARG1CB and DEXA:NR3C1 IEA Homo sapiens 27584 R-HSA-9009085 https://reactome.org/PathwayBrowser/#/R-HSA-9009085 DEXA:NR3C1 complex binds RUNX2 gene proximal promoter IEA Homo sapiens 27584 R-HSA-9625693 https://reactome.org/PathwayBrowser/#/R-HSA-9625693 TRIM63 gene expression is stimulated by FOXO1 and FOXO3 IEA Homo sapiens 27584 R-HSA-9625699 https://reactome.org/PathwayBrowser/#/R-HSA-9625699 FOXO1 and NR3C1 bind TRIM63 gene promoter IEA Homo sapiens 27584 R-HSA-9769345 https://reactome.org/PathwayBrowser/#/R-HSA-9769345 Activated glucocorticoid receptor represses NPAS4 gene transcription IEA Homo sapiens 27584 R-HSA-9769347 https://reactome.org/PathwayBrowser/#/R-HSA-9769347 Activated glucocorticoid receptor binds NPAS4 gene promoter IEA Homo sapiens 27584 R-MMU-1449687 https://reactome.org/PathwayBrowser/#/R-MMU-1449687 Corticosteroids bind to CBG in blood IEA Mus musculus 27584 R-MMU-193965 https://reactome.org/PathwayBrowser/#/R-MMU-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Mus musculus 27584 R-MMU-4341025 https://reactome.org/PathwayBrowser/#/R-MMU-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Mus musculus 27584 R-MMU-549409 https://reactome.org/PathwayBrowser/#/R-MMU-549409 Expression of Period-2 (Per2) TAS Mus musculus 27584 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 27584 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 27584 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 27584 R-MMU-5618099 https://reactome.org/PathwayBrowser/#/R-MMU-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Mus musculus 27584 R-MMU-9009091 https://reactome.org/PathwayBrowser/#/R-MMU-9009091 Nr3c1:DEXA binds Runx2 proximal promoter TAS Mus musculus 27584 R-MMU-9009102 https://reactome.org/PathwayBrowser/#/R-MMU-9009102 Runx2 gene expression from proximal (P2) promoter is stimulated by Runx2-P2 and inhibited by DEXA:Nr3c1 TAS Mus musculus 27584 R-MMU-9625700 https://reactome.org/PathwayBrowser/#/R-MMU-9625700 Foxo1 and Nr3c1 bind Trim63 gene promoter TAS Mus musculus 27584 R-MMU-9625730 https://reactome.org/PathwayBrowser/#/R-MMU-9625730 Trim63 gene expression is activated by Foxo1 and Nr3c1 TAS Mus musculus 27584 R-MMU-9769703 https://reactome.org/PathwayBrowser/#/R-MMU-9769703 Activated glucocorticoid receptor binds Npas4 gene promoter TAS Mus musculus 27584 R-MMU-9769713 https://reactome.org/PathwayBrowser/#/R-MMU-9769713 Activated glucocorticoid receptor represses Npas4 gene transcription TAS Mus musculus 27584 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 27584 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 27584 R-PFA-5618099 https://reactome.org/PathwayBrowser/#/R-PFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 27584 R-RNO-1449687 https://reactome.org/PathwayBrowser/#/R-RNO-1449687 Corticosteroids bind to CBG in blood IEA Rattus norvegicus 27584 R-RNO-193965 https://reactome.org/PathwayBrowser/#/R-RNO-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Rattus norvegicus 27584 R-RNO-4341025 https://reactome.org/PathwayBrowser/#/R-RNO-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Rattus norvegicus 27584 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 27584 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 27584 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 27584 R-RNO-5618099 https://reactome.org/PathwayBrowser/#/R-RNO-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Rattus norvegicus 27584 R-SSC-1449687 https://reactome.org/PathwayBrowser/#/R-SSC-1449687 Corticosteroids bind to CBG in blood IEA Sus scrofa 27584 R-SSC-193965 https://reactome.org/PathwayBrowser/#/R-SSC-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Sus scrofa 27584 R-SSC-4341025 https://reactome.org/PathwayBrowser/#/R-SSC-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Sus scrofa 27584 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 27584 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 27584 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 27584 R-SSC-5618099 https://reactome.org/PathwayBrowser/#/R-SSC-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Sus scrofa 27584 R-XTR-1449687 https://reactome.org/PathwayBrowser/#/R-XTR-1449687 Corticosteroids bind to CBG in blood IEA Xenopus tropicalis 27584 R-XTR-193965 https://reactome.org/PathwayBrowser/#/R-XTR-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Xenopus tropicalis 27584 R-XTR-4341025 https://reactome.org/PathwayBrowser/#/R-XTR-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Xenopus tropicalis 27584 R-XTR-5618099 https://reactome.org/PathwayBrowser/#/R-XTR-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 27595 R-BTA-2161614 https://reactome.org/PathwayBrowser/#/R-BTA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Bos taurus 27595 R-CEL-2161614 https://reactome.org/PathwayBrowser/#/R-CEL-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Caenorhabditis elegans 27595 R-DDI-2161614 https://reactome.org/PathwayBrowser/#/R-DDI-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Dictyostelium discoideum 27595 R-DME-2161614 https://reactome.org/PathwayBrowser/#/R-DME-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Drosophila melanogaster 27595 R-HSA-2161614 https://reactome.org/PathwayBrowser/#/R-HSA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 TAS Homo sapiens 27595 R-MMU-2161614 https://reactome.org/PathwayBrowser/#/R-MMU-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Mus musculus 27595 R-RNO-2161614 https://reactome.org/PathwayBrowser/#/R-RNO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Rattus norvegicus 27595 R-SCE-2161614 https://reactome.org/PathwayBrowser/#/R-SCE-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Saccharomyces cerevisiae 27595 R-SPO-2161614 https://reactome.org/PathwayBrowser/#/R-SPO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Schizosaccharomyces pombe 27595 R-SSC-2161614 https://reactome.org/PathwayBrowser/#/R-SSC-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Sus scrofa 27595 R-XTR-2161614 https://reactome.org/PathwayBrowser/#/R-XTR-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Xenopus tropicalis 27613 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 27613 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 27613 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 27613 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 27613 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 27613 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 27613 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 27613 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 27613 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 27613 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 27613 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 27613 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 27613 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 27613 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 27613 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 27613 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 27613 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 27613 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 27613 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 27613 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 27613 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 27613 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 27613 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 27613 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 27613 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 27613 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 27613 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 27613 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 27613 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 27613 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 27613 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 27613 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 27613 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 27613 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 27613 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 27613 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 27613 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 27613 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 27613 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 27613 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 27613 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 27613 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 27632 R-MTU-879273 https://reactome.org/PathwayBrowser/#/R-MTU-879273 mycothiol conjugates with electrophilic xenobiotic TAS Mycobacterium tuberculosis 27638 R-BTA-2534096 https://reactome.org/PathwayBrowser/#/R-BTA-2534096 METAP1/2 demethylates GNAT1 IEA Bos taurus 27638 R-BTA-880007 https://reactome.org/PathwayBrowser/#/R-BTA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Bos taurus 27638 R-CEL-880007 https://reactome.org/PathwayBrowser/#/R-CEL-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Caenorhabditis elegans 27638 R-CFA-2534096 https://reactome.org/PathwayBrowser/#/R-CFA-2534096 METAP1/2 demethylates GNAT1 IEA Canis familiaris 27638 R-CFA-880007 https://reactome.org/PathwayBrowser/#/R-CFA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Canis familiaris 27638 R-DDI-2534096 https://reactome.org/PathwayBrowser/#/R-DDI-2534096 METAP1/2 demethylates GNAT1 IEA Dictyostelium discoideum 27638 R-DDI-880007 https://reactome.org/PathwayBrowser/#/R-DDI-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Dictyostelium discoideum 27638 R-DME-880007 https://reactome.org/PathwayBrowser/#/R-DME-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Drosophila melanogaster 27638 R-DRE-2534096 https://reactome.org/PathwayBrowser/#/R-DRE-2534096 METAP1/2 demethylates GNAT1 IEA Danio rerio 27638 R-DRE-880007 https://reactome.org/PathwayBrowser/#/R-DRE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Danio rerio 27638 R-GGA-880007 https://reactome.org/PathwayBrowser/#/R-GGA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus 27638 R-HSA-2534096 https://reactome.org/PathwayBrowser/#/R-HSA-2534096 METAP1/2 demethylates GNAT1 TAS Homo sapiens 27638 R-HSA-880007 https://reactome.org/PathwayBrowser/#/R-HSA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 TAS Homo sapiens 27638 R-MMU-2534096 https://reactome.org/PathwayBrowser/#/R-MMU-2534096 METAP1/2 demethylates GNAT1 IEA Mus musculus 27638 R-MMU-880007 https://reactome.org/PathwayBrowser/#/R-MMU-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Mus musculus 27638 R-RNO-2534096 https://reactome.org/PathwayBrowser/#/R-RNO-2534096 METAP1/2 demethylates GNAT1 IEA Rattus norvegicus 27638 R-RNO-880007 https://reactome.org/PathwayBrowser/#/R-RNO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Rattus norvegicus 27638 R-SCE-2534096 https://reactome.org/PathwayBrowser/#/R-SCE-2534096 METAP1/2 demethylates GNAT1 IEA Saccharomyces cerevisiae 27638 R-SCE-880007 https://reactome.org/PathwayBrowser/#/R-SCE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Saccharomyces cerevisiae 27638 R-SPO-2534096 https://reactome.org/PathwayBrowser/#/R-SPO-2534096 METAP1/2 demethylates GNAT1 IEA Schizosaccharomyces pombe 27638 R-SPO-880007 https://reactome.org/PathwayBrowser/#/R-SPO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Schizosaccharomyces pombe 27638 R-SSC-2534096 https://reactome.org/PathwayBrowser/#/R-SSC-2534096 METAP1/2 demethylates GNAT1 IEA Sus scrofa 27638 R-SSC-880007 https://reactome.org/PathwayBrowser/#/R-SSC-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa 27638 R-XTR-2534096 https://reactome.org/PathwayBrowser/#/R-XTR-2534096 METAP1/2 demethylates GNAT1 IEA Xenopus tropicalis 27638 R-XTR-880007 https://reactome.org/PathwayBrowser/#/R-XTR-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Xenopus tropicalis 27641 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 27641 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 27641 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 27641 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 27641 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 27641 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 27641 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 27641 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 27641 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 27641 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 27647 R-BTA-140355 https://reactome.org/PathwayBrowser/#/R-BTA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Bos taurus 27647 R-BTA-140359 https://reactome.org/PathwayBrowser/#/R-BTA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Bos taurus 27647 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 27647 R-BTA-2309787 https://reactome.org/PathwayBrowser/#/R-BTA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Bos taurus 27647 R-CFA-140355 https://reactome.org/PathwayBrowser/#/R-CFA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Canis familiaris 27647 R-CFA-140359 https://reactome.org/PathwayBrowser/#/R-CFA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Canis familiaris 27647 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 27647 R-CFA-2309787 https://reactome.org/PathwayBrowser/#/R-CFA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Canis familiaris 27647 R-DRE-140355 https://reactome.org/PathwayBrowser/#/R-DRE-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Danio rerio 27647 R-DRE-140359 https://reactome.org/PathwayBrowser/#/R-DRE-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Danio rerio 27647 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 27647 R-DRE-2309787 https://reactome.org/PathwayBrowser/#/R-DRE-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Danio rerio 27647 R-GGA-140355 https://reactome.org/PathwayBrowser/#/R-GGA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Gallus gallus 27647 R-GGA-140359 https://reactome.org/PathwayBrowser/#/R-GGA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Gallus gallus 27647 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 27647 R-GGA-2309787 https://reactome.org/PathwayBrowser/#/R-GGA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Gallus gallus 27647 R-HSA-140355 https://reactome.org/PathwayBrowser/#/R-HSA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 TAS Homo sapiens 27647 R-HSA-140359 https://reactome.org/PathwayBrowser/#/R-HSA-140359 PGG2 is reduced to PGH2 by PTGS1 TAS Homo sapiens 27647 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 27647 R-HSA-2309787 https://reactome.org/PathwayBrowser/#/R-HSA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 TAS Homo sapiens 27647 R-MMU-140355 https://reactome.org/PathwayBrowser/#/R-MMU-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Mus musculus 27647 R-MMU-140359 https://reactome.org/PathwayBrowser/#/R-MMU-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Mus musculus 27647 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 27647 R-MMU-2309787 https://reactome.org/PathwayBrowser/#/R-MMU-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Mus musculus 27647 R-RNO-140355 https://reactome.org/PathwayBrowser/#/R-RNO-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Rattus norvegicus 27647 R-RNO-140359 https://reactome.org/PathwayBrowser/#/R-RNO-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Rattus norvegicus 27647 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 27647 R-RNO-2309787 https://reactome.org/PathwayBrowser/#/R-RNO-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Rattus norvegicus 27647 R-SSC-140355 https://reactome.org/PathwayBrowser/#/R-SSC-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Sus scrofa 27647 R-SSC-140359 https://reactome.org/PathwayBrowser/#/R-SSC-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Sus scrofa 27647 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 27647 R-SSC-2309787 https://reactome.org/PathwayBrowser/#/R-SSC-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Sus scrofa 27647 R-XTR-140355 https://reactome.org/PathwayBrowser/#/R-XTR-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Xenopus tropicalis 27647 R-XTR-140359 https://reactome.org/PathwayBrowser/#/R-XTR-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Xenopus tropicalis 27647 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 27647 R-XTR-2309787 https://reactome.org/PathwayBrowser/#/R-XTR-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Xenopus tropicalis 27648 R-BTA-77321 https://reactome.org/PathwayBrowser/#/R-BTA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Bos taurus 27648 R-BTA-77323 https://reactome.org/PathwayBrowser/#/R-BTA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Bos taurus 27648 R-CEL-77321 https://reactome.org/PathwayBrowser/#/R-CEL-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Caenorhabditis elegans 27648 R-CEL-77323 https://reactome.org/PathwayBrowser/#/R-CEL-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Caenorhabditis elegans 27648 R-CFA-77321 https://reactome.org/PathwayBrowser/#/R-CFA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Canis familiaris 27648 R-CFA-77323 https://reactome.org/PathwayBrowser/#/R-CFA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Canis familiaris 27648 R-DME-77321 https://reactome.org/PathwayBrowser/#/R-DME-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Drosophila melanogaster 27648 R-DRE-77321 https://reactome.org/PathwayBrowser/#/R-DRE-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Danio rerio 27648 R-DRE-77323 https://reactome.org/PathwayBrowser/#/R-DRE-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Danio rerio 27648 R-GGA-77321 https://reactome.org/PathwayBrowser/#/R-GGA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Gallus gallus 27648 R-GGA-77323 https://reactome.org/PathwayBrowser/#/R-GGA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Gallus gallus 27648 R-HSA-77321 https://reactome.org/PathwayBrowser/#/R-HSA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA TAS Homo sapiens 27648 R-HSA-77323 https://reactome.org/PathwayBrowser/#/R-HSA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H TAS Homo sapiens 27648 R-MMU-77321 https://reactome.org/PathwayBrowser/#/R-MMU-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Mus musculus 27648 R-MMU-77323 https://reactome.org/PathwayBrowser/#/R-MMU-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Mus musculus 27648 R-RNO-77321 https://reactome.org/PathwayBrowser/#/R-RNO-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Rattus norvegicus 27648 R-RNO-77323 https://reactome.org/PathwayBrowser/#/R-RNO-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Rattus norvegicus 27648 R-SSC-77321 https://reactome.org/PathwayBrowser/#/R-SSC-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Sus scrofa 27648 R-SSC-77323 https://reactome.org/PathwayBrowser/#/R-SSC-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Sus scrofa 27648 R-XTR-77321 https://reactome.org/PathwayBrowser/#/R-XTR-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Xenopus tropicalis 27648 R-XTR-77323 https://reactome.org/PathwayBrowser/#/R-XTR-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Xenopus tropicalis 27662 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 27662 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 27662 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 27662 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 27662 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 27662 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 27662 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 27662 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 27662 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 27662 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 27662 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 27662 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 27662 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 27662 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 27662 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 27662 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 27662 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 27662 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 27668 R-BTA-77254 https://reactome.org/PathwayBrowser/#/R-BTA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Bos taurus 27668 R-BTA-77256 https://reactome.org/PathwayBrowser/#/R-BTA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Bos taurus 27668 R-CEL-77254 https://reactome.org/PathwayBrowser/#/R-CEL-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 27668 R-CEL-77256 https://reactome.org/PathwayBrowser/#/R-CEL-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Caenorhabditis elegans 27668 R-CFA-77254 https://reactome.org/PathwayBrowser/#/R-CFA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Canis familiaris 27668 R-CFA-77256 https://reactome.org/PathwayBrowser/#/R-CFA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Canis familiaris 27668 R-DDI-77256 https://reactome.org/PathwayBrowser/#/R-DDI-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Dictyostelium discoideum 27668 R-DME-77256 https://reactome.org/PathwayBrowser/#/R-DME-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Drosophila melanogaster 27668 R-DRE-77254 https://reactome.org/PathwayBrowser/#/R-DRE-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Danio rerio 27668 R-GGA-77254 https://reactome.org/PathwayBrowser/#/R-GGA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Gallus gallus 27668 R-HSA-77254 https://reactome.org/PathwayBrowser/#/R-HSA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H TAS Homo sapiens 27668 R-HSA-77256 https://reactome.org/PathwayBrowser/#/R-HSA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA TAS Homo sapiens 27668 R-MMU-77254 https://reactome.org/PathwayBrowser/#/R-MMU-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Mus musculus 27668 R-MMU-77256 https://reactome.org/PathwayBrowser/#/R-MMU-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Mus musculus 27668 R-RNO-77254 https://reactome.org/PathwayBrowser/#/R-RNO-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Rattus norvegicus 27668 R-RNO-77256 https://reactome.org/PathwayBrowser/#/R-RNO-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Rattus norvegicus 27668 R-SSC-77254 https://reactome.org/PathwayBrowser/#/R-SSC-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Sus scrofa 27668 R-SSC-77256 https://reactome.org/PathwayBrowser/#/R-SSC-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Sus scrofa 27668 R-XTR-77254 https://reactome.org/PathwayBrowser/#/R-XTR-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Xenopus tropicalis 27668 R-XTR-77256 https://reactome.org/PathwayBrowser/#/R-XTR-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Xenopus tropicalis 27692 R-HSA-1467209 https://reactome.org/PathwayBrowser/#/R-HSA-1467209 Binding of defensins to lipid II TAS Homo sapiens 27700 R-BTA-6786720 https://reactome.org/PathwayBrowser/#/R-BTA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Bos taurus 27700 R-CFA-6786720 https://reactome.org/PathwayBrowser/#/R-CFA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Canis familiaris 27700 R-DRE-6786720 https://reactome.org/PathwayBrowser/#/R-DRE-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Danio rerio 27700 R-GGA-6786720 https://reactome.org/PathwayBrowser/#/R-GGA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Gallus gallus 27700 R-HSA-6786720 https://reactome.org/PathwayBrowser/#/R-HSA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA TAS Homo sapiens 27700 R-MMU-6786720 https://reactome.org/PathwayBrowser/#/R-MMU-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Mus musculus 27700 R-RNO-6786720 https://reactome.org/PathwayBrowser/#/R-RNO-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Rattus norvegicus 27700 R-SCE-6786720 https://reactome.org/PathwayBrowser/#/R-SCE-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Saccharomyces cerevisiae 27700 R-SSC-6786720 https://reactome.org/PathwayBrowser/#/R-SSC-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Sus scrofa 27721 R-BTA-77274 https://reactome.org/PathwayBrowser/#/R-BTA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Bos taurus 27721 R-BTA-77277 https://reactome.org/PathwayBrowser/#/R-BTA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Bos taurus 27721 R-CEL-77277 https://reactome.org/PathwayBrowser/#/R-CEL-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Caenorhabditis elegans 27721 R-CFA-77274 https://reactome.org/PathwayBrowser/#/R-CFA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Canis familiaris 27721 R-CFA-77277 https://reactome.org/PathwayBrowser/#/R-CFA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Canis familiaris 27721 R-DME-77277 https://reactome.org/PathwayBrowser/#/R-DME-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Drosophila melanogaster 27721 R-DRE-77274 https://reactome.org/PathwayBrowser/#/R-DRE-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Danio rerio 27721 R-DRE-77277 https://reactome.org/PathwayBrowser/#/R-DRE-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Danio rerio 27721 R-GGA-77274 https://reactome.org/PathwayBrowser/#/R-GGA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Gallus gallus 27721 R-GGA-77277 https://reactome.org/PathwayBrowser/#/R-GGA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Gallus gallus 27721 R-HSA-77274 https://reactome.org/PathwayBrowser/#/R-HSA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 TAS Homo sapiens 27721 R-HSA-77277 https://reactome.org/PathwayBrowser/#/R-HSA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA TAS Homo sapiens 27721 R-MMU-77274 https://reactome.org/PathwayBrowser/#/R-MMU-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Mus musculus 27721 R-MMU-77277 https://reactome.org/PathwayBrowser/#/R-MMU-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Mus musculus 27721 R-RNO-77274 https://reactome.org/PathwayBrowser/#/R-RNO-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 27721 R-RNO-77277 https://reactome.org/PathwayBrowser/#/R-RNO-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Rattus norvegicus 27721 R-SSC-77274 https://reactome.org/PathwayBrowser/#/R-SSC-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Sus scrofa 27721 R-SSC-77277 https://reactome.org/PathwayBrowser/#/R-SSC-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Sus scrofa 27721 R-XTR-77274 https://reactome.org/PathwayBrowser/#/R-XTR-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Xenopus tropicalis 27721 R-XTR-77277 https://reactome.org/PathwayBrowser/#/R-XTR-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Xenopus tropicalis 27732 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 27732 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 27732 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 27732 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 27732 R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 27732 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 27732 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 27732 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 27732 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 27732 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 27732 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 27732 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 27732 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 27732 R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 27732 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 27732 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 27732 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 27732 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 27732 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 27732 R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 27732 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 27732 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 27732 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 27732 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 27732 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 27732 R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 27732 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 27732 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 27732 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 27732 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 27732 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 27732 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 27732 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 27732 R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 27732 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 27732 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 27732 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 27732 R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 27732 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 27732 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 27732 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 27732 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 27732 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 27732 R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 27732 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 27732 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 27732 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 27732 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 27732 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 27747 R-BTA-8959781 https://reactome.org/PathwayBrowser/#/R-BTA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Bos taurus 27747 R-CEL-8959781 https://reactome.org/PathwayBrowser/#/R-CEL-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Caenorhabditis elegans 27747 R-CFA-8959781 https://reactome.org/PathwayBrowser/#/R-CFA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Canis familiaris 27747 R-DME-8959781 https://reactome.org/PathwayBrowser/#/R-DME-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Drosophila melanogaster 27747 R-DRE-8959781 https://reactome.org/PathwayBrowser/#/R-DRE-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Danio rerio 27747 R-GGA-8959781 https://reactome.org/PathwayBrowser/#/R-GGA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Gallus gallus 27747 R-HSA-8959781 https://reactome.org/PathwayBrowser/#/R-HSA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix TAS Homo sapiens 27747 R-MMU-8959781 https://reactome.org/PathwayBrowser/#/R-MMU-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Mus musculus 27747 R-RNO-8959781 https://reactome.org/PathwayBrowser/#/R-RNO-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Rattus norvegicus 27747 R-XTR-8959781 https://reactome.org/PathwayBrowser/#/R-XTR-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Xenopus tropicalis 27754 R-BTA-70859 https://reactome.org/PathwayBrowser/#/R-BTA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Bos taurus 27754 R-BTA-70870 https://reactome.org/PathwayBrowser/#/R-BTA-70870 ECHS1 hydrates methacrylyl-CoA IEA Bos taurus 27754 R-CEL-70859 https://reactome.org/PathwayBrowser/#/R-CEL-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Caenorhabditis elegans 27754 R-CEL-70870 https://reactome.org/PathwayBrowser/#/R-CEL-70870 ECHS1 hydrates methacrylyl-CoA IEA Caenorhabditis elegans 27754 R-CFA-70859 https://reactome.org/PathwayBrowser/#/R-CFA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Canis familiaris 27754 R-CFA-70870 https://reactome.org/PathwayBrowser/#/R-CFA-70870 ECHS1 hydrates methacrylyl-CoA IEA Canis familiaris 27754 R-DDI-70859 https://reactome.org/PathwayBrowser/#/R-DDI-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Dictyostelium discoideum 27754 R-DDI-70870 https://reactome.org/PathwayBrowser/#/R-DDI-70870 ECHS1 hydrates methacrylyl-CoA IEA Dictyostelium discoideum 27754 R-DME-70870 https://reactome.org/PathwayBrowser/#/R-DME-70870 ECHS1 hydrates methacrylyl-CoA IEA Drosophila melanogaster 27754 R-DRE-70859 https://reactome.org/PathwayBrowser/#/R-DRE-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Danio rerio 27754 R-GGA-70859 https://reactome.org/PathwayBrowser/#/R-GGA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Gallus gallus 27754 R-HSA-70859 https://reactome.org/PathwayBrowser/#/R-HSA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 TAS Homo sapiens 27754 R-HSA-70870 https://reactome.org/PathwayBrowser/#/R-HSA-70870 ECHS1 hydrates methacrylyl-CoA TAS Homo sapiens 27754 R-MMU-70859 https://reactome.org/PathwayBrowser/#/R-MMU-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Mus musculus 27754 R-MMU-70870 https://reactome.org/PathwayBrowser/#/R-MMU-70870 ECHS1 hydrates methacrylyl-CoA IEA Mus musculus 27754 R-RNO-70859 https://reactome.org/PathwayBrowser/#/R-RNO-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Rattus norvegicus 27754 R-RNO-70870 https://reactome.org/PathwayBrowser/#/R-RNO-70870 ECHS1 hydrates methacrylyl-CoA IEA Rattus norvegicus 27754 R-SSC-70859 https://reactome.org/PathwayBrowser/#/R-SSC-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Sus scrofa 27754 R-SSC-70870 https://reactome.org/PathwayBrowser/#/R-SSC-70870 ECHS1 hydrates methacrylyl-CoA IEA Sus scrofa 27754 R-XTR-70859 https://reactome.org/PathwayBrowser/#/R-XTR-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Xenopus tropicalis 27754 R-XTR-70870 https://reactome.org/PathwayBrowser/#/R-XTR-70870 ECHS1 hydrates methacrylyl-CoA IEA Xenopus tropicalis 27760 R-HSA-2408543 https://reactome.org/PathwayBrowser/#/R-HSA-2408543 SeCysta is hydrolysed to Sec by PXLP-K212-CTH IEA Homo sapiens 27760 R-HSA-2408559 https://reactome.org/PathwayBrowser/#/R-HSA-2408559 SeHCys and Ser are dehydrated into SeCysta by CBS IEA Homo sapiens 27760 R-RNO-2408502 https://reactome.org/PathwayBrowser/#/R-RNO-2408502 SeCysta is hydrolysed to Sec by PXLP-K211-Cth TAS Rattus norvegicus 27760 R-RNO-2408533 https://reactome.org/PathwayBrowser/#/R-RNO-2408533 SeHCys and Ser are dehydrated into SeCysta by Cbs TAS Rattus norvegicus 27812 R-HSA-2408539 https://reactome.org/PathwayBrowser/#/R-HSA-2408539 MeSec is hydrolysed to MeSeH by PXLP-K212-CTH IEA Homo sapiens 27812 R-RNO-2408538 https://reactome.org/PathwayBrowser/#/R-RNO-2408538 MeSec is hydrolysed to MeSeH by PXLP-K211-Cth TAS Rattus norvegicus 27814 R-HSA-2161567 https://reactome.org/PathwayBrowser/#/R-HSA-2161567 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 IEA Homo sapiens 27814 R-SSC-2161617 https://reactome.org/PathwayBrowser/#/R-SSC-2161617 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 TAS Sus scrofa 27820 R-HSA-2161659 https://reactome.org/PathwayBrowser/#/R-HSA-2161659 PGE2 is dehydrated to PGA2 TAS Homo sapiens 27820 R-HSA-2161666 https://reactome.org/PathwayBrowser/#/R-HSA-2161666 PGA2 is isomerised to PGC2 TAS Homo sapiens 27820 R-HSA-2161668 https://reactome.org/PathwayBrowser/#/R-HSA-2161668 PGA2 is dehydrated to 15d-PGA2 IEA Homo sapiens 27820 R-MMU-2161646 https://reactome.org/PathwayBrowser/#/R-MMU-2161646 PGA2 is dehydrated to 15d-PGA2 TAS Mus musculus 27823 R-BTA-380608 https://reactome.org/PathwayBrowser/#/R-BTA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Bos taurus 27823 R-CEL-380608 https://reactome.org/PathwayBrowser/#/R-CEL-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Caenorhabditis elegans 27823 R-CFA-380608 https://reactome.org/PathwayBrowser/#/R-CFA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Canis familiaris 27823 R-DDI-380608 https://reactome.org/PathwayBrowser/#/R-DDI-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Dictyostelium discoideum 27823 R-DME-380608 https://reactome.org/PathwayBrowser/#/R-DME-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Drosophila melanogaster 27823 R-DRE-380608 https://reactome.org/PathwayBrowser/#/R-DRE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Danio rerio 27823 R-GGA-380608 https://reactome.org/PathwayBrowser/#/R-GGA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Gallus gallus 27823 R-HSA-380608 https://reactome.org/PathwayBrowser/#/R-HSA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid TAS Homo sapiens 27823 R-MMU-380608 https://reactome.org/PathwayBrowser/#/R-MMU-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Mus musculus 27823 R-RNO-380608 https://reactome.org/PathwayBrowser/#/R-RNO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Rattus norvegicus 27823 R-SCE-380608 https://reactome.org/PathwayBrowser/#/R-SCE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Saccharomyces cerevisiae 27823 R-SPO-380608 https://reactome.org/PathwayBrowser/#/R-SPO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Schizosaccharomyces pombe 27823 R-SSC-380608 https://reactome.org/PathwayBrowser/#/R-SSC-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Sus scrofa 27823 R-XTR-380608 https://reactome.org/PathwayBrowser/#/R-XTR-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Xenopus tropicalis 27847 R-BTA-209815 https://reactome.org/PathwayBrowser/#/R-BTA-209815 Tyrosine is monoiodinated IEA Bos taurus 27847 R-BTA-209921 https://reactome.org/PathwayBrowser/#/R-BTA-209921 Monoiodinated tyrosine can be deiodinated IEA Bos taurus 27847 R-BTA-209925 https://reactome.org/PathwayBrowser/#/R-BTA-209925 DIT and MIT combine to form triiodothyronine IEA Bos taurus 27847 R-CEL-209815 https://reactome.org/PathwayBrowser/#/R-CEL-209815 Tyrosine is monoiodinated IEA Caenorhabditis elegans 27847 R-CEL-209921 https://reactome.org/PathwayBrowser/#/R-CEL-209921 Monoiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 27847 R-CEL-209925 https://reactome.org/PathwayBrowser/#/R-CEL-209925 DIT and MIT combine to form triiodothyronine IEA Caenorhabditis elegans 27847 R-CFA-209815 https://reactome.org/PathwayBrowser/#/R-CFA-209815 Tyrosine is monoiodinated IEA Canis familiaris 27847 R-CFA-209921 https://reactome.org/PathwayBrowser/#/R-CFA-209921 Monoiodinated tyrosine can be deiodinated IEA Canis familiaris 27847 R-CFA-209925 https://reactome.org/PathwayBrowser/#/R-CFA-209925 DIT and MIT combine to form triiodothyronine IEA Canis familiaris 27847 R-DDI-209815 https://reactome.org/PathwayBrowser/#/R-DDI-209815 Tyrosine is monoiodinated IEA Dictyostelium discoideum 27847 R-DDI-209925 https://reactome.org/PathwayBrowser/#/R-DDI-209925 DIT and MIT combine to form triiodothyronine IEA Dictyostelium discoideum 27847 R-DME-209815 https://reactome.org/PathwayBrowser/#/R-DME-209815 Tyrosine is monoiodinated IEA Drosophila melanogaster 27847 R-DME-209921 https://reactome.org/PathwayBrowser/#/R-DME-209921 Monoiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 27847 R-DME-209925 https://reactome.org/PathwayBrowser/#/R-DME-209925 DIT and MIT combine to form triiodothyronine IEA Drosophila melanogaster 27847 R-DRE-209921 https://reactome.org/PathwayBrowser/#/R-DRE-209921 Monoiodinated tyrosine can be deiodinated IEA Danio rerio 27847 R-GGA-209815 https://reactome.org/PathwayBrowser/#/R-GGA-209815 Tyrosine is monoiodinated IEA Gallus gallus 27847 R-GGA-209921 https://reactome.org/PathwayBrowser/#/R-GGA-209921 Monoiodinated tyrosine can be deiodinated IEA Gallus gallus 27847 R-GGA-209925 https://reactome.org/PathwayBrowser/#/R-GGA-209925 DIT and MIT combine to form triiodothyronine IEA Gallus gallus 27847 R-HSA-209815 https://reactome.org/PathwayBrowser/#/R-HSA-209815 Tyrosine is monoiodinated TAS Homo sapiens 27847 R-HSA-209921 https://reactome.org/PathwayBrowser/#/R-HSA-209921 Monoiodinated tyrosine can be deiodinated TAS Homo sapiens 27847 R-HSA-209925 https://reactome.org/PathwayBrowser/#/R-HSA-209925 DIT and MIT combine to form triiodothyronine TAS Homo sapiens 27847 R-MMU-209815 https://reactome.org/PathwayBrowser/#/R-MMU-209815 Tyrosine is monoiodinated IEA Mus musculus 27847 R-MMU-209921 https://reactome.org/PathwayBrowser/#/R-MMU-209921 Monoiodinated tyrosine can be deiodinated IEA Mus musculus 27847 R-MMU-209925 https://reactome.org/PathwayBrowser/#/R-MMU-209925 DIT and MIT combine to form triiodothyronine IEA Mus musculus 27847 R-RNO-209815 https://reactome.org/PathwayBrowser/#/R-RNO-209815 Tyrosine is monoiodinated IEA Rattus norvegicus 27847 R-RNO-209921 https://reactome.org/PathwayBrowser/#/R-RNO-209921 Monoiodinated tyrosine can be deiodinated IEA Rattus norvegicus 27847 R-RNO-209925 https://reactome.org/PathwayBrowser/#/R-RNO-209925 DIT and MIT combine to form triiodothyronine IEA Rattus norvegicus 27847 R-SSC-209815 https://reactome.org/PathwayBrowser/#/R-SSC-209815 Tyrosine is monoiodinated IEA Sus scrofa 27847 R-SSC-209921 https://reactome.org/PathwayBrowser/#/R-SSC-209921 Monoiodinated tyrosine can be deiodinated IEA Sus scrofa 27847 R-SSC-209925 https://reactome.org/PathwayBrowser/#/R-SSC-209925 DIT and MIT combine to form triiodothyronine IEA Sus scrofa 27847 R-XTR-209921 https://reactome.org/PathwayBrowser/#/R-XTR-209921 Monoiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 27852 R-BTA-374909 https://reactome.org/PathwayBrowser/#/R-BTA-374909 Catabolism of Noradrenaline IEA Bos taurus 27852 R-CFA-374909 https://reactome.org/PathwayBrowser/#/R-CFA-374909 Catabolism of Noradrenaline IEA Canis familiaris 27852 R-DDI-374909 https://reactome.org/PathwayBrowser/#/R-DDI-374909 Catabolism of Noradrenaline IEA Dictyostelium discoideum 27852 R-GGA-374909 https://reactome.org/PathwayBrowser/#/R-GGA-374909 Catabolism of Noradrenaline IEA Gallus gallus 27852 R-HSA-374909 https://reactome.org/PathwayBrowser/#/R-HSA-374909 Catabolism of Noradrenaline TAS Homo sapiens 27852 R-MMU-374909 https://reactome.org/PathwayBrowser/#/R-MMU-374909 Catabolism of Noradrenaline IEA Mus musculus 27852 R-RNO-374909 https://reactome.org/PathwayBrowser/#/R-RNO-374909 Catabolism of Noradrenaline IEA Rattus norvegicus 27852 R-SSC-374909 https://reactome.org/PathwayBrowser/#/R-SSC-374909 Catabolism of Noradrenaline IEA Sus scrofa 27868 R-BTA-77254 https://reactome.org/PathwayBrowser/#/R-BTA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Bos taurus 27868 R-BTA-77309 https://reactome.org/PathwayBrowser/#/R-BTA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Bos taurus 27868 R-CEL-77254 https://reactome.org/PathwayBrowser/#/R-CEL-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 27868 R-CEL-77309 https://reactome.org/PathwayBrowser/#/R-CEL-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Caenorhabditis elegans 27868 R-CFA-77254 https://reactome.org/PathwayBrowser/#/R-CFA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Canis familiaris 27868 R-CFA-77309 https://reactome.org/PathwayBrowser/#/R-CFA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Canis familiaris 27868 R-DME-77309 https://reactome.org/PathwayBrowser/#/R-DME-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Drosophila melanogaster 27868 R-DRE-77254 https://reactome.org/PathwayBrowser/#/R-DRE-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Danio rerio 27868 R-DRE-77309 https://reactome.org/PathwayBrowser/#/R-DRE-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Danio rerio 27868 R-GGA-77254 https://reactome.org/PathwayBrowser/#/R-GGA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Gallus gallus 27868 R-GGA-77309 https://reactome.org/PathwayBrowser/#/R-GGA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Gallus gallus 27868 R-HSA-77254 https://reactome.org/PathwayBrowser/#/R-HSA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H TAS Homo sapiens 27868 R-HSA-77309 https://reactome.org/PathwayBrowser/#/R-HSA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA TAS Homo sapiens 27868 R-MMU-77254 https://reactome.org/PathwayBrowser/#/R-MMU-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Mus musculus 27868 R-MMU-77309 https://reactome.org/PathwayBrowser/#/R-MMU-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Mus musculus 27868 R-RNO-77254 https://reactome.org/PathwayBrowser/#/R-RNO-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Rattus norvegicus 27868 R-RNO-77309 https://reactome.org/PathwayBrowser/#/R-RNO-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Rattus norvegicus 27868 R-SSC-77254 https://reactome.org/PathwayBrowser/#/R-SSC-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Sus scrofa 27868 R-SSC-77309 https://reactome.org/PathwayBrowser/#/R-SSC-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Sus scrofa 27868 R-XTR-77254 https://reactome.org/PathwayBrowser/#/R-XTR-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Xenopus tropicalis 27868 R-XTR-77309 https://reactome.org/PathwayBrowser/#/R-XTR-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Xenopus tropicalis 27870 R-BTA-3076905 https://reactome.org/PathwayBrowser/#/R-BTA-3076905 Extracellular BTD hydrolyses BCTN IEA Bos taurus 27870 R-BTA-4167509 https://reactome.org/PathwayBrowser/#/R-BTA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Bos taurus 27870 R-CFA-3076905 https://reactome.org/PathwayBrowser/#/R-CFA-3076905 Extracellular BTD hydrolyses BCTN IEA Canis familiaris 27870 R-CFA-4167509 https://reactome.org/PathwayBrowser/#/R-CFA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Canis familiaris 27870 R-DDI-3076905 https://reactome.org/PathwayBrowser/#/R-DDI-3076905 Extracellular BTD hydrolyses BCTN IEA Dictyostelium discoideum 27870 R-DDI-4167509 https://reactome.org/PathwayBrowser/#/R-DDI-4167509 Mitochondrial BTD hydrolyses BCTN IEA Dictyostelium discoideum 27870 R-DME-3076905 https://reactome.org/PathwayBrowser/#/R-DME-3076905 Extracellular BTD hydrolyses BCTN IEA Drosophila melanogaster 27870 R-DME-4167509 https://reactome.org/PathwayBrowser/#/R-DME-4167509 Mitochondrial BTD hydrolyses BCTN IEA Drosophila melanogaster 27870 R-DRE-3076905 https://reactome.org/PathwayBrowser/#/R-DRE-3076905 Extracellular BTD hydrolyses BCTN IEA Danio rerio 27870 R-DRE-4167509 https://reactome.org/PathwayBrowser/#/R-DRE-4167509 Mitochondrial BTD hydrolyses BCTN IEA Danio rerio 27870 R-GGA-3076905 https://reactome.org/PathwayBrowser/#/R-GGA-3076905 Extracellular BTD hydrolyses BCTN IEA Gallus gallus 27870 R-GGA-4167509 https://reactome.org/PathwayBrowser/#/R-GGA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Gallus gallus 27870 R-HSA-3065958 https://reactome.org/PathwayBrowser/#/R-HSA-3065958 An unknown protease degrades ACACA TAS Homo sapiens 27870 R-HSA-3065959 https://reactome.org/PathwayBrowser/#/R-HSA-3065959 An unknown protease degrades hCBXs TAS Homo sapiens 27870 R-HSA-3076881 https://reactome.org/PathwayBrowser/#/R-HSA-3076881 BCTN translocates to extracellular region TAS Homo sapiens 27870 R-HSA-3076905 https://reactome.org/PathwayBrowser/#/R-HSA-3076905 Extracellular BTD hydrolyses BCTN TAS Homo sapiens 27870 R-HSA-3325540 https://reactome.org/PathwayBrowser/#/R-HSA-3325540 Defective extracellular BTD does not hydrolyse BCTN TAS Homo sapiens 27870 R-HSA-4167501 https://reactome.org/PathwayBrowser/#/R-HSA-4167501 An unknown protease degrades ACACB TAS Homo sapiens 27870 R-HSA-4167509 https://reactome.org/PathwayBrowser/#/R-HSA-4167509 Mitochondrial BTD hydrolyses BCTN TAS Homo sapiens 27870 R-HSA-4225086 https://reactome.org/PathwayBrowser/#/R-HSA-4225086 Defective mitochondrial BTD does not hydrolyse BCTN TAS Homo sapiens 27870 R-MMU-3076905 https://reactome.org/PathwayBrowser/#/R-MMU-3076905 Extracellular BTD hydrolyses BCTN IEA Mus musculus 27870 R-MMU-4167509 https://reactome.org/PathwayBrowser/#/R-MMU-4167509 Mitochondrial BTD hydrolyses BCTN IEA Mus musculus 27870 R-RNO-3076905 https://reactome.org/PathwayBrowser/#/R-RNO-3076905 Extracellular BTD hydrolyses BCTN IEA Rattus norvegicus 27870 R-RNO-4167509 https://reactome.org/PathwayBrowser/#/R-RNO-4167509 Mitochondrial BTD hydrolyses BCTN IEA Rattus norvegicus 27870 R-SSC-3076905 https://reactome.org/PathwayBrowser/#/R-SSC-3076905 Extracellular BTD hydrolyses BCTN IEA Sus scrofa 27870 R-SSC-4167509 https://reactome.org/PathwayBrowser/#/R-SSC-4167509 Mitochondrial BTD hydrolyses BCTN IEA Sus scrofa 27870 R-XTR-3076905 https://reactome.org/PathwayBrowser/#/R-XTR-3076905 Extracellular BTD hydrolyses BCTN IEA Xenopus tropicalis 27870 R-XTR-4167509 https://reactome.org/PathwayBrowser/#/R-XTR-4167509 Mitochondrial BTD hydrolyses BCTN IEA Xenopus tropicalis 2788 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 2788 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 2788 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 2788 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 2788 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 2788 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 2788 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 2788 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 2788 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 2788 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 2788 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 27881 R-BTA-8936519 https://reactome.org/PathwayBrowser/#/R-BTA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Bos taurus 27881 R-CFA-8936519 https://reactome.org/PathwayBrowser/#/R-CFA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Canis familiaris 27881 R-GGA-8936519 https://reactome.org/PathwayBrowser/#/R-GGA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Gallus gallus 27881 R-HSA-8936519 https://reactome.org/PathwayBrowser/#/R-HSA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones TAS Homo sapiens 27881 R-MMU-8936519 https://reactome.org/PathwayBrowser/#/R-MMU-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Mus musculus 27881 R-RNO-8936519 https://reactome.org/PathwayBrowser/#/R-RNO-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Rattus norvegicus 27881 R-SSC-8936519 https://reactome.org/PathwayBrowser/#/R-SSC-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Sus scrofa 27881 R-XTR-8936519 https://reactome.org/PathwayBrowser/#/R-XTR-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Xenopus tropicalis 27889 R-BTA-189439 https://reactome.org/PathwayBrowser/#/R-BTA-189439 ALAD condenses 2 dALAs to form PBG IEA Bos taurus 27889 R-BTA-189465 https://reactome.org/PathwayBrowser/#/R-BTA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Bos taurus 27889 R-CEL-189465 https://reactome.org/PathwayBrowser/#/R-CEL-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Caenorhabditis elegans 27889 R-CFA-189439 https://reactome.org/PathwayBrowser/#/R-CFA-189439 ALAD condenses 2 dALAs to form PBG IEA Canis familiaris 27889 R-CFA-189465 https://reactome.org/PathwayBrowser/#/R-CFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Canis familiaris 27889 R-DDI-189439 https://reactome.org/PathwayBrowser/#/R-DDI-189439 ALAD condenses 2 dALAs to form PBG IEA Dictyostelium discoideum 27889 R-DDI-189465 https://reactome.org/PathwayBrowser/#/R-DDI-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Dictyostelium discoideum 27889 R-DME-189439 https://reactome.org/PathwayBrowser/#/R-DME-189439 ALAD condenses 2 dALAs to form PBG IEA Drosophila melanogaster 27889 R-DME-189465 https://reactome.org/PathwayBrowser/#/R-DME-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Drosophila melanogaster 27889 R-DRE-189439 https://reactome.org/PathwayBrowser/#/R-DRE-189439 ALAD condenses 2 dALAs to form PBG IEA Danio rerio 27889 R-DRE-189465 https://reactome.org/PathwayBrowser/#/R-DRE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Danio rerio 27889 R-GGA-189439 https://reactome.org/PathwayBrowser/#/R-GGA-189439 ALAD condenses 2 dALAs to form PBG IEA Gallus gallus 27889 R-GGA-189465 https://reactome.org/PathwayBrowser/#/R-GGA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Gallus gallus 27889 R-HSA-189439 https://reactome.org/PathwayBrowser/#/R-HSA-189439 ALAD condenses 2 dALAs to form PBG TAS Homo sapiens 27889 R-HSA-189465 https://reactome.org/PathwayBrowser/#/R-HSA-189465 FECH binds Fe2+ to PRIN9 to form heme TAS Homo sapiens 27889 R-HSA-190141 https://reactome.org/PathwayBrowser/#/R-HSA-190141 ALAD binds to Pb2+ TAS Homo sapiens 27889 R-MMU-189439 https://reactome.org/PathwayBrowser/#/R-MMU-189439 ALAD condenses 2 dALAs to form PBG IEA Mus musculus 27889 R-MMU-189465 https://reactome.org/PathwayBrowser/#/R-MMU-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Mus musculus 27889 R-PFA-189439 https://reactome.org/PathwayBrowser/#/R-PFA-189439 ALAD condenses 2 dALAs to form PBG IEA Plasmodium falciparum 27889 R-PFA-189465 https://reactome.org/PathwayBrowser/#/R-PFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Plasmodium falciparum 27889 R-RNO-189439 https://reactome.org/PathwayBrowser/#/R-RNO-189439 ALAD condenses 2 dALAs to form PBG IEA Rattus norvegicus 27889 R-RNO-189465 https://reactome.org/PathwayBrowser/#/R-RNO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Rattus norvegicus 27889 R-SCE-189439 https://reactome.org/PathwayBrowser/#/R-SCE-189439 ALAD condenses 2 dALAs to form PBG IEA Saccharomyces cerevisiae 27889 R-SCE-189465 https://reactome.org/PathwayBrowser/#/R-SCE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Saccharomyces cerevisiae 27889 R-SPO-189439 https://reactome.org/PathwayBrowser/#/R-SPO-189439 ALAD condenses 2 dALAs to form PBG IEA Schizosaccharomyces pombe 27889 R-SPO-189465 https://reactome.org/PathwayBrowser/#/R-SPO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Schizosaccharomyces pombe 27889 R-SSC-189439 https://reactome.org/PathwayBrowser/#/R-SSC-189439 ALAD condenses 2 dALAs to form PBG IEA Sus scrofa 27889 R-SSC-189465 https://reactome.org/PathwayBrowser/#/R-SSC-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Sus scrofa 27889 R-XTR-189439 https://reactome.org/PathwayBrowser/#/R-XTR-189439 ALAD condenses 2 dALAs to form PBG IEA Xenopus tropicalis 27905 R-BTA-158849 https://reactome.org/PathwayBrowser/#/R-BTA-158849 Phenol can form a sulfate conjugate IEA Bos taurus 27905 R-CFA-158849 https://reactome.org/PathwayBrowser/#/R-CFA-158849 Phenol can form a sulfate conjugate IEA Canis familiaris 27905 R-DME-158849 https://reactome.org/PathwayBrowser/#/R-DME-158849 Phenol can form a sulfate conjugate IEA Drosophila melanogaster 27905 R-DRE-158849 https://reactome.org/PathwayBrowser/#/R-DRE-158849 Phenol can form a sulfate conjugate IEA Danio rerio 27905 R-GGA-158849 https://reactome.org/PathwayBrowser/#/R-GGA-158849 Phenol can form a sulfate conjugate IEA Gallus gallus 27905 R-HSA-158849 https://reactome.org/PathwayBrowser/#/R-HSA-158849 Phenol can form a sulfate conjugate TAS Homo sapiens 27905 R-MMU-158849 https://reactome.org/PathwayBrowser/#/R-MMU-158849 Phenol can form a sulfate conjugate IEA Mus musculus 27905 R-RNO-158849 https://reactome.org/PathwayBrowser/#/R-RNO-158849 Phenol can form a sulfate conjugate IEA Rattus norvegicus 27905 R-SSC-158849 https://reactome.org/PathwayBrowser/#/R-SSC-158849 Phenol can form a sulfate conjugate IEA Sus scrofa 27905 R-XTR-158849 https://reactome.org/PathwayBrowser/#/R-XTR-158849 Phenol can form a sulfate conjugate IEA Xenopus tropicalis 27910 R-BTA-195664 https://reactome.org/PathwayBrowser/#/R-BTA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Bos taurus 27910 R-BTA-196402 https://reactome.org/PathwayBrowser/#/R-BTA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Bos taurus 27910 R-CEL-196402 https://reactome.org/PathwayBrowser/#/R-CEL-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Caenorhabditis elegans 27910 R-CFA-195664 https://reactome.org/PathwayBrowser/#/R-CFA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Canis familiaris 27910 R-CFA-196402 https://reactome.org/PathwayBrowser/#/R-CFA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Canis familiaris 27910 R-DRE-195664 https://reactome.org/PathwayBrowser/#/R-DRE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Danio rerio 27910 R-DRE-196402 https://reactome.org/PathwayBrowser/#/R-DRE-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Danio rerio 27910 R-GGA-195664 https://reactome.org/PathwayBrowser/#/R-GGA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Gallus gallus 27910 R-GGA-196402 https://reactome.org/PathwayBrowser/#/R-GGA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Gallus gallus 27910 R-HSA-195664 https://reactome.org/PathwayBrowser/#/R-HSA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol TAS Homo sapiens 27910 R-HSA-196402 https://reactome.org/PathwayBrowser/#/R-HSA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol TAS Homo sapiens 27910 R-MMU-195664 https://reactome.org/PathwayBrowser/#/R-MMU-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Mus musculus 27910 R-MMU-196402 https://reactome.org/PathwayBrowser/#/R-MMU-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Mus musculus 27910 R-RNO-195664 https://reactome.org/PathwayBrowser/#/R-RNO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Rattus norvegicus 27910 R-RNO-196402 https://reactome.org/PathwayBrowser/#/R-RNO-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Rattus norvegicus 27910 R-SCE-195664 https://reactome.org/PathwayBrowser/#/R-SCE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Saccharomyces cerevisiae 27910 R-SPO-195664 https://reactome.org/PathwayBrowser/#/R-SPO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Schizosaccharomyces pombe 27910 R-SSC-195664 https://reactome.org/PathwayBrowser/#/R-SSC-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Sus scrofa 27910 R-SSC-196402 https://reactome.org/PathwayBrowser/#/R-SSC-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Sus scrofa 27910 R-XTR-195664 https://reactome.org/PathwayBrowser/#/R-XTR-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Xenopus tropicalis 27910 R-XTR-196402 https://reactome.org/PathwayBrowser/#/R-XTR-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Xenopus tropicalis 27913 R-HSA-9640321 https://reactome.org/PathwayBrowser/#/R-HSA-9640321 2,3-DKG hydrolyses to ERU and oxalate TAS Homo sapiens 27923 R-BTA-1482546 https://reactome.org/PathwayBrowser/#/R-BTA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Bos taurus 27923 R-BTA-1482635 https://reactome.org/PathwayBrowser/#/R-BTA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Bos taurus 27923 R-BTA-1482847 https://reactome.org/PathwayBrowser/#/R-BTA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Bos taurus 27923 R-BTA-1482920 https://reactome.org/PathwayBrowser/#/R-BTA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Bos taurus 27923 R-CEL-1482546 https://reactome.org/PathwayBrowser/#/R-CEL-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Caenorhabditis elegans 27923 R-CEL-1482635 https://reactome.org/PathwayBrowser/#/R-CEL-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Caenorhabditis elegans 27923 R-CFA-1482635 https://reactome.org/PathwayBrowser/#/R-CFA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Canis familiaris 27923 R-CFA-1482847 https://reactome.org/PathwayBrowser/#/R-CFA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Canis familiaris 27923 R-CFA-1482920 https://reactome.org/PathwayBrowser/#/R-CFA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Canis familiaris 27923 R-DDI-1482635 https://reactome.org/PathwayBrowser/#/R-DDI-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Dictyostelium discoideum 27923 R-DME-1482546 https://reactome.org/PathwayBrowser/#/R-DME-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Drosophila melanogaster 27923 R-DME-1482635 https://reactome.org/PathwayBrowser/#/R-DME-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Drosophila melanogaster 27923 R-DRE-1482546 https://reactome.org/PathwayBrowser/#/R-DRE-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Danio rerio 27923 R-DRE-1482635 https://reactome.org/PathwayBrowser/#/R-DRE-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Danio rerio 27923 R-GGA-1482546 https://reactome.org/PathwayBrowser/#/R-GGA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Gallus gallus 27923 R-GGA-1482635 https://reactome.org/PathwayBrowser/#/R-GGA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Gallus gallus 27923 R-GGA-1482847 https://reactome.org/PathwayBrowser/#/R-GGA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Gallus gallus 27923 R-GGA-1482920 https://reactome.org/PathwayBrowser/#/R-GGA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Gallus gallus 27923 R-HSA-1482546 https://reactome.org/PathwayBrowser/#/R-HSA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) TAS Homo sapiens 27923 R-HSA-1482635 https://reactome.org/PathwayBrowser/#/R-HSA-1482635 2-acyl LPG is acylated to PG by LPGAT TAS Homo sapiens 27923 R-HSA-1482847 https://reactome.org/PathwayBrowser/#/R-HSA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) TAS Homo sapiens 27923 R-HSA-1482920 https://reactome.org/PathwayBrowser/#/R-HSA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] TAS Homo sapiens 27923 R-MMU-1482546 https://reactome.org/PathwayBrowser/#/R-MMU-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Mus musculus 27923 R-MMU-1482635 https://reactome.org/PathwayBrowser/#/R-MMU-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Mus musculus 27923 R-MMU-1482847 https://reactome.org/PathwayBrowser/#/R-MMU-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Mus musculus 27923 R-MMU-1482920 https://reactome.org/PathwayBrowser/#/R-MMU-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Mus musculus 27923 R-PFA-1482635 https://reactome.org/PathwayBrowser/#/R-PFA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Plasmodium falciparum 27923 R-RNO-1482546 https://reactome.org/PathwayBrowser/#/R-RNO-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Rattus norvegicus 27923 R-RNO-1482635 https://reactome.org/PathwayBrowser/#/R-RNO-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Rattus norvegicus 27923 R-RNO-1482847 https://reactome.org/PathwayBrowser/#/R-RNO-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Rattus norvegicus 27923 R-RNO-1482920 https://reactome.org/PathwayBrowser/#/R-RNO-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Rattus norvegicus 27923 R-SCE-1482546 https://reactome.org/PathwayBrowser/#/R-SCE-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Saccharomyces cerevisiae 27923 R-SCE-1482635 https://reactome.org/PathwayBrowser/#/R-SCE-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Saccharomyces cerevisiae 27923 R-SCE-1482847 https://reactome.org/PathwayBrowser/#/R-SCE-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Saccharomyces cerevisiae 27923 R-SCE-1482920 https://reactome.org/PathwayBrowser/#/R-SCE-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Saccharomyces cerevisiae 27923 R-SPO-1482546 https://reactome.org/PathwayBrowser/#/R-SPO-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Schizosaccharomyces pombe 27923 R-SPO-1482635 https://reactome.org/PathwayBrowser/#/R-SPO-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Schizosaccharomyces pombe 27923 R-SPO-1482847 https://reactome.org/PathwayBrowser/#/R-SPO-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Schizosaccharomyces pombe 27923 R-SPO-1482920 https://reactome.org/PathwayBrowser/#/R-SPO-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Schizosaccharomyces pombe 27923 R-SSC-1482546 https://reactome.org/PathwayBrowser/#/R-SSC-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Sus scrofa 27923 R-SSC-1482635 https://reactome.org/PathwayBrowser/#/R-SSC-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa 27923 R-SSC-1482847 https://reactome.org/PathwayBrowser/#/R-SSC-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Sus scrofa 27923 R-SSC-1482920 https://reactome.org/PathwayBrowser/#/R-SSC-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Sus scrofa 27923 R-XTR-1482635 https://reactome.org/PathwayBrowser/#/R-XTR-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Xenopus tropicalis 27923 R-XTR-1482847 https://reactome.org/PathwayBrowser/#/R-XTR-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Xenopus tropicalis 27923 R-XTR-1482920 https://reactome.org/PathwayBrowser/#/R-XTR-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Xenopus tropicalis 27931 R-BTA-188979 https://reactome.org/PathwayBrowser/#/R-BTA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Bos taurus 27931 R-BTA-189053 https://reactome.org/PathwayBrowser/#/R-BTA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Bos taurus 27931 R-BTA-191101 https://reactome.org/PathwayBrowser/#/R-BTA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Bos taurus 27931 R-BTA-191114 https://reactome.org/PathwayBrowser/#/R-BTA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Bos taurus 27931 R-BTA-191116 https://reactome.org/PathwayBrowser/#/R-BTA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Bos taurus 27931 R-CEL-188979 https://reactome.org/PathwayBrowser/#/R-CEL-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Caenorhabditis elegans 27931 R-CEL-189053 https://reactome.org/PathwayBrowser/#/R-CEL-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Caenorhabditis elegans 27931 R-CEL-191101 https://reactome.org/PathwayBrowser/#/R-CEL-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 27931 R-CEL-191114 https://reactome.org/PathwayBrowser/#/R-CEL-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Caenorhabditis elegans 27931 R-CEL-191116 https://reactome.org/PathwayBrowser/#/R-CEL-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Caenorhabditis elegans 27931 R-CFA-188979 https://reactome.org/PathwayBrowser/#/R-CFA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Canis familiaris 27931 R-CFA-189053 https://reactome.org/PathwayBrowser/#/R-CFA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Canis familiaris 27931 R-CFA-191101 https://reactome.org/PathwayBrowser/#/R-CFA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Canis familiaris 27931 R-CFA-191114 https://reactome.org/PathwayBrowser/#/R-CFA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Canis familiaris 27931 R-CFA-191116 https://reactome.org/PathwayBrowser/#/R-CFA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Canis familiaris 27931 R-DDI-189053 https://reactome.org/PathwayBrowser/#/R-DDI-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Dictyostelium discoideum 27931 R-DDI-191101 https://reactome.org/PathwayBrowser/#/R-DDI-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 27931 R-DDI-191116 https://reactome.org/PathwayBrowser/#/R-DDI-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Dictyostelium discoideum 27931 R-DME-188979 https://reactome.org/PathwayBrowser/#/R-DME-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Drosophila melanogaster 27931 R-DME-191114 https://reactome.org/PathwayBrowser/#/R-DME-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Drosophila melanogaster 27931 R-DRE-188979 https://reactome.org/PathwayBrowser/#/R-DRE-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Danio rerio 27931 R-DRE-191114 https://reactome.org/PathwayBrowser/#/R-DRE-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Danio rerio 27931 R-GGA-188979 https://reactome.org/PathwayBrowser/#/R-GGA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Gallus gallus 27931 R-GGA-189053 https://reactome.org/PathwayBrowser/#/R-GGA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Gallus gallus 27931 R-GGA-191101 https://reactome.org/PathwayBrowser/#/R-GGA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Gallus gallus 27931 R-GGA-191114 https://reactome.org/PathwayBrowser/#/R-GGA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Gallus gallus 27931 R-GGA-191116 https://reactome.org/PathwayBrowser/#/R-GGA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Gallus gallus 27931 R-HSA-188979 https://reactome.org/PathwayBrowser/#/R-HSA-188979 Digestion of linear starch (amylose) by extracellular amylase TAS Homo sapiens 27931 R-HSA-189053 https://reactome.org/PathwayBrowser/#/R-HSA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose TAS Homo sapiens 27931 R-HSA-191101 https://reactome.org/PathwayBrowser/#/R-HSA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) TAS Homo sapiens 27931 R-HSA-191114 https://reactome.org/PathwayBrowser/#/R-HSA-191114 Digestion of branched starch (amylopectin) by extracellular amylase TAS Homo sapiens 27931 R-HSA-191116 https://reactome.org/PathwayBrowser/#/R-HSA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) TAS Homo sapiens 27931 R-HSA-5659899 https://reactome.org/PathwayBrowser/#/R-HSA-5659899 Defective SI does not hydrolyze maltotriose IEA Homo sapiens 27931 R-MMU-188979 https://reactome.org/PathwayBrowser/#/R-MMU-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Mus musculus 27931 R-MMU-189053 https://reactome.org/PathwayBrowser/#/R-MMU-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Mus musculus 27931 R-MMU-191101 https://reactome.org/PathwayBrowser/#/R-MMU-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Mus musculus 27931 R-MMU-191114 https://reactome.org/PathwayBrowser/#/R-MMU-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Mus musculus 27931 R-MMU-191116 https://reactome.org/PathwayBrowser/#/R-MMU-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Mus musculus 27931 R-RNO-188979 https://reactome.org/PathwayBrowser/#/R-RNO-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Rattus norvegicus 27931 R-RNO-189053 https://reactome.org/PathwayBrowser/#/R-RNO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Rattus norvegicus 27931 R-RNO-191101 https://reactome.org/PathwayBrowser/#/R-RNO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 27931 R-RNO-191114 https://reactome.org/PathwayBrowser/#/R-RNO-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Rattus norvegicus 27931 R-SPO-189053 https://reactome.org/PathwayBrowser/#/R-SPO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Schizosaccharomyces pombe 27931 R-SPO-191101 https://reactome.org/PathwayBrowser/#/R-SPO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 27931 R-SPO-191116 https://reactome.org/PathwayBrowser/#/R-SPO-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Schizosaccharomyces pombe 27931 R-SSC-188979 https://reactome.org/PathwayBrowser/#/R-SSC-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Sus scrofa 27931 R-SSC-189053 https://reactome.org/PathwayBrowser/#/R-SSC-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Sus scrofa 27931 R-SSC-191101 https://reactome.org/PathwayBrowser/#/R-SSC-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Sus scrofa 27931 R-SSC-191114 https://reactome.org/PathwayBrowser/#/R-SSC-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Sus scrofa 27931 R-SSC-191116 https://reactome.org/PathwayBrowser/#/R-SSC-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Sus scrofa 27931 R-XTR-188979 https://reactome.org/PathwayBrowser/#/R-XTR-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Xenopus tropicalis 27931 R-XTR-191114 https://reactome.org/PathwayBrowser/#/R-XTR-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Xenopus tropicalis 27958 R-BTA-5693691 https://reactome.org/PathwayBrowser/#/R-BTA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Bos taurus 27958 R-CEL-5693691 https://reactome.org/PathwayBrowser/#/R-CEL-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Caenorhabditis elegans 27958 R-CFA-5693691 https://reactome.org/PathwayBrowser/#/R-CFA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Canis familiaris 27958 R-DDI-5693691 https://reactome.org/PathwayBrowser/#/R-DDI-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Dictyostelium discoideum 27958 R-DME-5693691 https://reactome.org/PathwayBrowser/#/R-DME-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Drosophila melanogaster 27958 R-DRE-5693691 https://reactome.org/PathwayBrowser/#/R-DRE-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Danio rerio 27958 R-GGA-5693691 https://reactome.org/PathwayBrowser/#/R-GGA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Gallus gallus 27958 R-HSA-5693691 https://reactome.org/PathwayBrowser/#/R-HSA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG TAS Homo sapiens 27958 R-MMU-5693691 https://reactome.org/PathwayBrowser/#/R-MMU-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Mus musculus 27958 R-RNO-5693691 https://reactome.org/PathwayBrowser/#/R-RNO-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Rattus norvegicus 27958 R-SSC-5693691 https://reactome.org/PathwayBrowser/#/R-SSC-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Sus scrofa 27958 R-XTR-5693691 https://reactome.org/PathwayBrowser/#/R-XTR-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Xenopus tropicalis 27974 R-BTA-9008258 https://reactome.org/PathwayBrowser/#/R-BTA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Bos taurus 27974 R-BTA-9008270 https://reactome.org/PathwayBrowser/#/R-BTA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Bos taurus 27974 R-BTA-9008271 https://reactome.org/PathwayBrowser/#/R-BTA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Bos taurus 27974 R-BTA-9008285 https://reactome.org/PathwayBrowser/#/R-BTA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Bos taurus 27974 R-BTA-9009526 https://reactome.org/PathwayBrowser/#/R-BTA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 27974 R-BTA-9009533 https://reactome.org/PathwayBrowser/#/R-BTA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Bos taurus 27974 R-BTA-9009536 https://reactome.org/PathwayBrowser/#/R-BTA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Bos taurus 27974 R-BTA-9009541 https://reactome.org/PathwayBrowser/#/R-BTA-9009541 ESR1 binds to TFF1 gene promoter IEA Bos taurus 27974 R-BTA-9023860 https://reactome.org/PathwayBrowser/#/R-BTA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Bos taurus 27974 R-BTA-9023861 https://reactome.org/PathwayBrowser/#/R-BTA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 27974 R-BTA-9023884 https://reactome.org/PathwayBrowser/#/R-BTA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Bos taurus 27974 R-CFA-9008258 https://reactome.org/PathwayBrowser/#/R-CFA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Canis familiaris 27974 R-CFA-9008270 https://reactome.org/PathwayBrowser/#/R-CFA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Canis familiaris 27974 R-CFA-9008271 https://reactome.org/PathwayBrowser/#/R-CFA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Canis familiaris 27974 R-CFA-9008285 https://reactome.org/PathwayBrowser/#/R-CFA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Canis familiaris 27974 R-CFA-9009526 https://reactome.org/PathwayBrowser/#/R-CFA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 27974 R-CFA-9009533 https://reactome.org/PathwayBrowser/#/R-CFA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Canis familiaris 27974 R-CFA-9009536 https://reactome.org/PathwayBrowser/#/R-CFA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Canis familiaris 27974 R-CFA-9009541 https://reactome.org/PathwayBrowser/#/R-CFA-9009541 ESR1 binds to TFF1 gene promoter IEA Canis familiaris 27974 R-CFA-9023860 https://reactome.org/PathwayBrowser/#/R-CFA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Canis familiaris 27974 R-CFA-9023861 https://reactome.org/PathwayBrowser/#/R-CFA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 27974 R-CFA-9023884 https://reactome.org/PathwayBrowser/#/R-CFA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Canis familiaris 27974 R-DDI-9023860 https://reactome.org/PathwayBrowser/#/R-DDI-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Dictyostelium discoideum 27974 R-DME-9008258 https://reactome.org/PathwayBrowser/#/R-DME-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Drosophila melanogaster 27974 R-DME-9008270 https://reactome.org/PathwayBrowser/#/R-DME-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Drosophila melanogaster 27974 R-DME-9008285 https://reactome.org/PathwayBrowser/#/R-DME-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Drosophila melanogaster 27974 R-DME-9009526 https://reactome.org/PathwayBrowser/#/R-DME-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 27974 R-DME-9009533 https://reactome.org/PathwayBrowser/#/R-DME-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Drosophila melanogaster 27974 R-DME-9009536 https://reactome.org/PathwayBrowser/#/R-DME-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Drosophila melanogaster 27974 R-DME-9009541 https://reactome.org/PathwayBrowser/#/R-DME-9009541 ESR1 binds to TFF1 gene promoter IEA Drosophila melanogaster 27974 R-DME-9023860 https://reactome.org/PathwayBrowser/#/R-DME-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Drosophila melanogaster 27974 R-DME-9023861 https://reactome.org/PathwayBrowser/#/R-DME-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 27974 R-DME-9023884 https://reactome.org/PathwayBrowser/#/R-DME-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Drosophila melanogaster 27974 R-DRE-9009526 https://reactome.org/PathwayBrowser/#/R-DRE-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Danio rerio 27974 R-DRE-9009533 https://reactome.org/PathwayBrowser/#/R-DRE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Danio rerio 27974 R-DRE-9009541 https://reactome.org/PathwayBrowser/#/R-DRE-9009541 ESR1 binds to TFF1 gene promoter IEA Danio rerio 27974 R-DRE-9023860 https://reactome.org/PathwayBrowser/#/R-DRE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Danio rerio 27974 R-GGA-9008258 https://reactome.org/PathwayBrowser/#/R-GGA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Gallus gallus 27974 R-GGA-9008270 https://reactome.org/PathwayBrowser/#/R-GGA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Gallus gallus 27974 R-GGA-9008285 https://reactome.org/PathwayBrowser/#/R-GGA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Gallus gallus 27974 R-GGA-9009533 https://reactome.org/PathwayBrowser/#/R-GGA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Gallus gallus 27974 R-GGA-9009536 https://reactome.org/PathwayBrowser/#/R-GGA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Gallus gallus 27974 R-GGA-9009541 https://reactome.org/PathwayBrowser/#/R-GGA-9009541 ESR1 binds to TFF1 gene promoter IEA Gallus gallus 27974 R-GGA-9023860 https://reactome.org/PathwayBrowser/#/R-GGA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Gallus gallus 27974 R-GGA-9023884 https://reactome.org/PathwayBrowser/#/R-GGA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Gallus gallus 27974 R-HSA-9008258 https://reactome.org/PathwayBrowser/#/R-HSA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene TAS Homo sapiens 27974 R-HSA-9008267 https://reactome.org/PathwayBrowser/#/R-HSA-9008267 ESR1 binds to TGFA gene promoter TAS Homo sapiens 27974 R-HSA-9008270 https://reactome.org/PathwayBrowser/#/R-HSA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene TAS Homo sapiens 27974 R-HSA-9008271 https://reactome.org/PathwayBrowser/#/R-HSA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter TAS Homo sapiens 27974 R-HSA-9008285 https://reactome.org/PathwayBrowser/#/R-HSA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 TAS Homo sapiens 27974 R-HSA-9008315 https://reactome.org/PathwayBrowser/#/R-HSA-9008315 TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen TAS Homo sapiens 27974 R-HSA-9009526 https://reactome.org/PathwayBrowser/#/R-HSA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 27974 R-HSA-9009533 https://reactome.org/PathwayBrowser/#/R-HSA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter TAS Homo sapiens 27974 R-HSA-9009536 https://reactome.org/PathwayBrowser/#/R-HSA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter TAS Homo sapiens 27974 R-HSA-9009541 https://reactome.org/PathwayBrowser/#/R-HSA-9009541 ESR1 binds to TFF1 gene promoter TAS Homo sapiens 27974 R-HSA-9023859 https://reactome.org/PathwayBrowser/#/R-HSA-9023859 Estrogen-responsive TFF1 gene expression TAS Homo sapiens 27974 R-HSA-9023860 https://reactome.org/PathwayBrowser/#/R-HSA-9023860 Histone acetyltransferases are recruited to the TFF1 gene TAS Homo sapiens 27974 R-HSA-9023861 https://reactome.org/PathwayBrowser/#/R-HSA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 27974 R-HSA-9023884 https://reactome.org/PathwayBrowser/#/R-HSA-9023884 NCOA1 recruits EP300 to TGFA promoter TAS Homo sapiens 27974 R-MMU-9008258 https://reactome.org/PathwayBrowser/#/R-MMU-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Mus musculus 27974 R-MMU-9008270 https://reactome.org/PathwayBrowser/#/R-MMU-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Mus musculus 27974 R-MMU-9008271 https://reactome.org/PathwayBrowser/#/R-MMU-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Mus musculus 27974 R-MMU-9008285 https://reactome.org/PathwayBrowser/#/R-MMU-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Mus musculus 27974 R-MMU-9009526 https://reactome.org/PathwayBrowser/#/R-MMU-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 27974 R-MMU-9009533 https://reactome.org/PathwayBrowser/#/R-MMU-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Mus musculus 27974 R-MMU-9009536 https://reactome.org/PathwayBrowser/#/R-MMU-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Mus musculus 27974 R-MMU-9009541 https://reactome.org/PathwayBrowser/#/R-MMU-9009541 ESR1 binds to TFF1 gene promoter IEA Mus musculus 27974 R-MMU-9023860 https://reactome.org/PathwayBrowser/#/R-MMU-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Mus musculus 27974 R-MMU-9023861 https://reactome.org/PathwayBrowser/#/R-MMU-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 27974 R-MMU-9023884 https://reactome.org/PathwayBrowser/#/R-MMU-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Mus musculus 27974 R-RNO-9008258 https://reactome.org/PathwayBrowser/#/R-RNO-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Rattus norvegicus 27974 R-RNO-9008270 https://reactome.org/PathwayBrowser/#/R-RNO-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Rattus norvegicus 27974 R-RNO-9008271 https://reactome.org/PathwayBrowser/#/R-RNO-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Rattus norvegicus 27974 R-RNO-9008285 https://reactome.org/PathwayBrowser/#/R-RNO-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Rattus norvegicus 27974 R-RNO-9009526 https://reactome.org/PathwayBrowser/#/R-RNO-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 27974 R-RNO-9009533 https://reactome.org/PathwayBrowser/#/R-RNO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Rattus norvegicus 27974 R-RNO-9009536 https://reactome.org/PathwayBrowser/#/R-RNO-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Rattus norvegicus 27974 R-RNO-9009541 https://reactome.org/PathwayBrowser/#/R-RNO-9009541 ESR1 binds to TFF1 gene promoter IEA Rattus norvegicus 27974 R-RNO-9023860 https://reactome.org/PathwayBrowser/#/R-RNO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Rattus norvegicus 27974 R-RNO-9023861 https://reactome.org/PathwayBrowser/#/R-RNO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 27974 R-RNO-9023884 https://reactome.org/PathwayBrowser/#/R-RNO-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Rattus norvegicus 27974 R-SCE-9009533 https://reactome.org/PathwayBrowser/#/R-SCE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Saccharomyces cerevisiae 27974 R-SCE-9023860 https://reactome.org/PathwayBrowser/#/R-SCE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Saccharomyces cerevisiae 27974 R-SCE-9023861 https://reactome.org/PathwayBrowser/#/R-SCE-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Saccharomyces cerevisiae 27974 R-SPO-9009533 https://reactome.org/PathwayBrowser/#/R-SPO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Schizosaccharomyces pombe 27974 R-SPO-9023860 https://reactome.org/PathwayBrowser/#/R-SPO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Schizosaccharomyces pombe 27974 R-SPO-9023861 https://reactome.org/PathwayBrowser/#/R-SPO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Schizosaccharomyces pombe 27974 R-SSC-9008258 https://reactome.org/PathwayBrowser/#/R-SSC-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Sus scrofa 27974 R-SSC-9008270 https://reactome.org/PathwayBrowser/#/R-SSC-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Sus scrofa 27974 R-SSC-9008271 https://reactome.org/PathwayBrowser/#/R-SSC-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Sus scrofa 27974 R-SSC-9008285 https://reactome.org/PathwayBrowser/#/R-SSC-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Sus scrofa 27974 R-SSC-9009526 https://reactome.org/PathwayBrowser/#/R-SSC-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 27974 R-SSC-9009536 https://reactome.org/PathwayBrowser/#/R-SSC-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Sus scrofa 27974 R-SSC-9009541 https://reactome.org/PathwayBrowser/#/R-SSC-9009541 ESR1 binds to TFF1 gene promoter IEA Sus scrofa 27974 R-SSC-9023860 https://reactome.org/PathwayBrowser/#/R-SSC-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Sus scrofa 27974 R-SSC-9023861 https://reactome.org/PathwayBrowser/#/R-SSC-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 27974 R-SSC-9023884 https://reactome.org/PathwayBrowser/#/R-SSC-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Sus scrofa 27974 R-XTR-9008258 https://reactome.org/PathwayBrowser/#/R-XTR-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Xenopus tropicalis 27974 R-XTR-9008285 https://reactome.org/PathwayBrowser/#/R-XTR-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Xenopus tropicalis 27974 R-XTR-9023860 https://reactome.org/PathwayBrowser/#/R-XTR-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Xenopus tropicalis 27979 R-BTA-2046092 https://reactome.org/PathwayBrowser/#/R-BTA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Bos taurus 27979 R-BTA-2046094 https://reactome.org/PathwayBrowser/#/R-BTA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Bos taurus 27979 R-CEL-2046092 https://reactome.org/PathwayBrowser/#/R-CEL-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Caenorhabditis elegans 27979 R-CEL-2046094 https://reactome.org/PathwayBrowser/#/R-CEL-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Caenorhabditis elegans 27979 R-CFA-2046092 https://reactome.org/PathwayBrowser/#/R-CFA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Canis familiaris 27979 R-CFA-2046094 https://reactome.org/PathwayBrowser/#/R-CFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Canis familiaris 27979 R-DDI-2046094 https://reactome.org/PathwayBrowser/#/R-DDI-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Dictyostelium discoideum 27979 R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster 27979 R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio 27979 R-GGA-2046092 https://reactome.org/PathwayBrowser/#/R-GGA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Gallus gallus 27979 R-GGA-2046094 https://reactome.org/PathwayBrowser/#/R-GGA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Gallus gallus 27979 R-HSA-2046092 https://reactome.org/PathwayBrowser/#/R-HSA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA TAS Homo sapiens 27979 R-HSA-2046094 https://reactome.org/PathwayBrowser/#/R-HSA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA TAS Homo sapiens 27979 R-MMU-2046092 https://reactome.org/PathwayBrowser/#/R-MMU-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Mus musculus 27979 R-MMU-2046094 https://reactome.org/PathwayBrowser/#/R-MMU-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Mus musculus 27979 R-PFA-2046094 https://reactome.org/PathwayBrowser/#/R-PFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Plasmodium falciparum 27979 R-RNO-2046092 https://reactome.org/PathwayBrowser/#/R-RNO-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Rattus norvegicus 27979 R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus 27979 R-SCE-2046094 https://reactome.org/PathwayBrowser/#/R-SCE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Saccharomyces cerevisiae 27979 R-SPO-2046094 https://reactome.org/PathwayBrowser/#/R-SPO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Schizosaccharomyces pombe 27979 R-SSC-2046092 https://reactome.org/PathwayBrowser/#/R-SSC-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Sus scrofa 27979 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa 27979 R-XTR-2046092 https://reactome.org/PathwayBrowser/#/R-XTR-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Xenopus tropicalis 27979 R-XTR-2046094 https://reactome.org/PathwayBrowser/#/R-XTR-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Xenopus tropicalis 27983 R-BTA-110229 https://reactome.org/PathwayBrowser/#/R-BTA-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Bos taurus 27983 R-BTA-5649673 https://reactome.org/PathwayBrowser/#/R-BTA-5649673 NEIL1 cleaves FapyA from damaged DNA IEA Bos taurus 27983 R-CEL-110229 https://reactome.org/PathwayBrowser/#/R-CEL-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Caenorhabditis elegans 27983 R-CFA-110229 https://reactome.org/PathwayBrowser/#/R-CFA-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Canis familiaris 27983 R-CFA-5649673 https://reactome.org/PathwayBrowser/#/R-CFA-5649673 NEIL1 cleaves FapyA from damaged DNA IEA Canis familiaris 27983 R-DDI-110229 https://reactome.org/PathwayBrowser/#/R-DDI-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Dictyostelium discoideum 27983 R-DME-110229 https://reactome.org/PathwayBrowser/#/R-DME-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Drosophila melanogaster 27983 R-DRE-5649673 https://reactome.org/PathwayBrowser/#/R-DRE-5649673 NEIL1 cleaves FapyA from damaged DNA IEA Danio rerio 27983 R-GGA-110229 https://reactome.org/PathwayBrowser/#/R-GGA-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Gallus gallus 27983 R-GGA-5649673 https://reactome.org/PathwayBrowser/#/R-GGA-5649673 NEIL1 cleaves FapyA from damaged DNA IEA Gallus gallus 27983 R-HSA-110229 https://reactome.org/PathwayBrowser/#/R-HSA-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase TAS Homo sapiens 27983 R-HSA-5649673 https://reactome.org/PathwayBrowser/#/R-HSA-5649673 NEIL1 cleaves FapyA from damaged DNA TAS Homo sapiens 27983 R-MMU-110229 https://reactome.org/PathwayBrowser/#/R-MMU-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Mus musculus 27983 R-MMU-5649673 https://reactome.org/PathwayBrowser/#/R-MMU-5649673 NEIL1 cleaves FapyA from damaged DNA IEA Mus musculus 27983 R-PFA-110229 https://reactome.org/PathwayBrowser/#/R-PFA-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Plasmodium falciparum 27983 R-RNO-110229 https://reactome.org/PathwayBrowser/#/R-RNO-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Rattus norvegicus 27983 R-RNO-5649673 https://reactome.org/PathwayBrowser/#/R-RNO-5649673 NEIL1 cleaves FapyA from damaged DNA IEA Rattus norvegicus 27983 R-SCE-110229 https://reactome.org/PathwayBrowser/#/R-SCE-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Saccharomyces cerevisiae 27983 R-SPO-110229 https://reactome.org/PathwayBrowser/#/R-SPO-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Schizosaccharomyces pombe 27983 R-SSC-110229 https://reactome.org/PathwayBrowser/#/R-SSC-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Sus scrofa 27983 R-SSC-5649673 https://reactome.org/PathwayBrowser/#/R-SSC-5649673 NEIL1 cleaves FapyA from damaged DNA IEA Sus scrofa 27983 R-XTR-110229 https://reactome.org/PathwayBrowser/#/R-XTR-110229 Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase IEA Xenopus tropicalis 27983 R-XTR-5649673 https://reactome.org/PathwayBrowser/#/R-XTR-5649673 NEIL1 cleaves FapyA from damaged DNA IEA Xenopus tropicalis 27997 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 27997 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 27997 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 27997 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 27997 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 27997 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 27997 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 27997 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 27997 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 27997 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 27997 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 27997 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 27997 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 27997 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 27997 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 27997 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 27997 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 27997 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 27997 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 27997 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 27997 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 27997 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 27997 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 27997 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 27997 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 27997 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 27997 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 27997 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 27997 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 27997 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 27997 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 27997 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 27997 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 27997 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 27997 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 27999 R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 27999 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 27999 R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 27999 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 27999 R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 27999 R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 27999 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 27999 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 27999 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 27999 R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 27999 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 27999 R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 27999 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 27999 R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 27999 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 27999 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 27999 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 27999 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 28002 R-BTA-109338 https://reactome.org/PathwayBrowser/#/R-BTA-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Bos taurus 28002 R-CFA-109338 https://reactome.org/PathwayBrowser/#/R-CFA-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Canis familiaris 28002 R-DME-109338 https://reactome.org/PathwayBrowser/#/R-DME-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Drosophila melanogaster 28002 R-GGA-109338 https://reactome.org/PathwayBrowser/#/R-GGA-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Gallus gallus 28002 R-HSA-109338 https://reactome.org/PathwayBrowser/#/R-HSA-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA TAS Homo sapiens 28002 R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 28002 R-MMU-109338 https://reactome.org/PathwayBrowser/#/R-MMU-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Mus musculus 28002 R-RNO-109338 https://reactome.org/PathwayBrowser/#/R-RNO-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Rattus norvegicus 28002 R-SSC-109338 https://reactome.org/PathwayBrowser/#/R-SSC-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Sus scrofa 28002 R-XTR-109338 https://reactome.org/PathwayBrowser/#/R-XTR-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Xenopus tropicalis 28009 R-BTA-166726 https://reactome.org/PathwayBrowser/#/R-BTA-166726 Activation of MASPs IEA Bos taurus 28009 R-BTA-166753 https://reactome.org/PathwayBrowser/#/R-BTA-166753 Conversion of C4 into C4a and C4b IEA Bos taurus 28009 R-BTA-166792 https://reactome.org/PathwayBrowser/#/R-BTA-166792 Conversion of C2 into C2a and C2b IEA Bos taurus 28009 R-BTA-2855054 https://reactome.org/PathwayBrowser/#/R-BTA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Bos taurus 28009 R-BTA-2855125 https://reactome.org/PathwayBrowser/#/R-BTA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Bos taurus 28009 R-BTA-8862320 https://reactome.org/PathwayBrowser/#/R-BTA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Bos taurus 28009 R-CFA-166726 https://reactome.org/PathwayBrowser/#/R-CFA-166726 Activation of MASPs IEA Canis familiaris 28009 R-CFA-166753 https://reactome.org/PathwayBrowser/#/R-CFA-166753 Conversion of C4 into C4a and C4b IEA Canis familiaris 28009 R-CFA-166792 https://reactome.org/PathwayBrowser/#/R-CFA-166792 Conversion of C2 into C2a and C2b IEA Canis familiaris 28009 R-CFA-2855054 https://reactome.org/PathwayBrowser/#/R-CFA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Canis familiaris 28009 R-CFA-2855125 https://reactome.org/PathwayBrowser/#/R-CFA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Canis familiaris 28009 R-CFA-8862320 https://reactome.org/PathwayBrowser/#/R-CFA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Canis familiaris 28009 R-DDI-8862320 https://reactome.org/PathwayBrowser/#/R-DDI-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Dictyostelium discoideum 28009 R-DME-8862320 https://reactome.org/PathwayBrowser/#/R-DME-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Drosophila melanogaster 28009 R-DRE-8862320 https://reactome.org/PathwayBrowser/#/R-DRE-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Danio rerio 28009 R-GGA-166726 https://reactome.org/PathwayBrowser/#/R-GGA-166726 Activation of MASPs IEA Gallus gallus 28009 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus 28009 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus 28009 R-GGA-2855054 https://reactome.org/PathwayBrowser/#/R-GGA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Gallus gallus 28009 R-GGA-2855125 https://reactome.org/PathwayBrowser/#/R-GGA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Gallus gallus 28009 R-GGA-8862320 https://reactome.org/PathwayBrowser/#/R-GGA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Gallus gallus 28009 R-HSA-166726 https://reactome.org/PathwayBrowser/#/R-HSA-166726 Activation of MASPs TAS Homo sapiens 28009 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens 28009 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens 28009 R-HSA-2855054 https://reactome.org/PathwayBrowser/#/R-HSA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface TAS Homo sapiens 28009 R-HSA-2855077 https://reactome.org/PathwayBrowser/#/R-HSA-2855077 Ficolin-3 binds to molecular patterns on the target cell surface TAS Homo sapiens 28009 R-HSA-2855125 https://reactome.org/PathwayBrowser/#/R-HSA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface TAS Homo sapiens 28009 R-HSA-6789208 https://reactome.org/PathwayBrowser/#/R-HSA-6789208 HOCl-induced glycosaminoglycan fragmentation TAS Homo sapiens 28009 R-HSA-8862320 https://reactome.org/PathwayBrowser/#/R-HSA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall TAS Homo sapiens 28009 R-MMU-166726 https://reactome.org/PathwayBrowser/#/R-MMU-166726 Activation of MASPs IEA Mus musculus 28009 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus 28009 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus 28009 R-MMU-2855054 https://reactome.org/PathwayBrowser/#/R-MMU-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Mus musculus 28009 R-MMU-2855125 https://reactome.org/PathwayBrowser/#/R-MMU-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Mus musculus 28009 R-MMU-8862320 https://reactome.org/PathwayBrowser/#/R-MMU-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Mus musculus 28009 R-RNO-166726 https://reactome.org/PathwayBrowser/#/R-RNO-166726 Activation of MASPs IEA Rattus norvegicus 28009 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus 28009 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus 28009 R-RNO-2855054 https://reactome.org/PathwayBrowser/#/R-RNO-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Rattus norvegicus 28009 R-RNO-2855125 https://reactome.org/PathwayBrowser/#/R-RNO-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Rattus norvegicus 28009 R-RNO-8862320 https://reactome.org/PathwayBrowser/#/R-RNO-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Rattus norvegicus 28009 R-SSC-166726 https://reactome.org/PathwayBrowser/#/R-SSC-166726 Activation of MASPs IEA Sus scrofa 28009 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa 28009 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa 28009 R-SSC-2855054 https://reactome.org/PathwayBrowser/#/R-SSC-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Sus scrofa 28009 R-SSC-2855125 https://reactome.org/PathwayBrowser/#/R-SSC-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Sus scrofa 28009 R-SSC-8862320 https://reactome.org/PathwayBrowser/#/R-SSC-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Sus scrofa 28009 R-XTR-166726 https://reactome.org/PathwayBrowser/#/R-XTR-166726 Activation of MASPs IEA Xenopus tropicalis 28009 R-XTR-166753 https://reactome.org/PathwayBrowser/#/R-XTR-166753 Conversion of C4 into C4a and C4b IEA Xenopus tropicalis 28009 R-XTR-166792 https://reactome.org/PathwayBrowser/#/R-XTR-166792 Conversion of C2 into C2a and C2b IEA Xenopus tropicalis 28009 R-XTR-2855054 https://reactome.org/PathwayBrowser/#/R-XTR-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Xenopus tropicalis 28009 R-XTR-2855125 https://reactome.org/PathwayBrowser/#/R-XTR-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Xenopus tropicalis 28009 R-XTR-8862320 https://reactome.org/PathwayBrowser/#/R-XTR-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Xenopus tropicalis 28010 R-BTA-200661 https://reactome.org/PathwayBrowser/#/R-BTA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Bos taurus 28010 R-BTA-200711 https://reactome.org/PathwayBrowser/#/R-BTA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Bos taurus 28010 R-BTA-200740 https://reactome.org/PathwayBrowser/#/R-BTA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Bos taurus 28010 R-BTA-6808487 https://reactome.org/PathwayBrowser/#/R-BTA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 28010 R-BTA-6808496 https://reactome.org/PathwayBrowser/#/R-BTA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 28010 R-CEL-200661 https://reactome.org/PathwayBrowser/#/R-CEL-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Caenorhabditis elegans 28010 R-CEL-200711 https://reactome.org/PathwayBrowser/#/R-CEL-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Caenorhabditis elegans 28010 R-CEL-200740 https://reactome.org/PathwayBrowser/#/R-CEL-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Caenorhabditis elegans 28010 R-CEL-6808487 https://reactome.org/PathwayBrowser/#/R-CEL-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 28010 R-CEL-6808496 https://reactome.org/PathwayBrowser/#/R-CEL-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 28010 R-CFA-200661 https://reactome.org/PathwayBrowser/#/R-CFA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Canis familiaris 28010 R-CFA-200711 https://reactome.org/PathwayBrowser/#/R-CFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Canis familiaris 28010 R-CFA-200740 https://reactome.org/PathwayBrowser/#/R-CFA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Canis familiaris 28010 R-CFA-6808487 https://reactome.org/PathwayBrowser/#/R-CFA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 28010 R-CFA-6808496 https://reactome.org/PathwayBrowser/#/R-CFA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 28010 R-DDI-200661 https://reactome.org/PathwayBrowser/#/R-DDI-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Dictyostelium discoideum 28010 R-DDI-200711 https://reactome.org/PathwayBrowser/#/R-DDI-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Dictyostelium discoideum 28010 R-DDI-200740 https://reactome.org/PathwayBrowser/#/R-DDI-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Dictyostelium discoideum 28010 R-DME-200661 https://reactome.org/PathwayBrowser/#/R-DME-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Drosophila melanogaster 28010 R-DME-200711 https://reactome.org/PathwayBrowser/#/R-DME-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Drosophila melanogaster 28010 R-DME-200740 https://reactome.org/PathwayBrowser/#/R-DME-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Drosophila melanogaster 28010 R-DME-6808487 https://reactome.org/PathwayBrowser/#/R-DME-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 28010 R-DME-6808496 https://reactome.org/PathwayBrowser/#/R-DME-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 28010 R-DRE-200661 https://reactome.org/PathwayBrowser/#/R-DRE-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio 28010 R-DRE-200711 https://reactome.org/PathwayBrowser/#/R-DRE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Danio rerio 28010 R-DRE-200740 https://reactome.org/PathwayBrowser/#/R-DRE-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Danio rerio 28010 R-DRE-6808496 https://reactome.org/PathwayBrowser/#/R-DRE-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Danio rerio 28010 R-GGA-200661 https://reactome.org/PathwayBrowser/#/R-GGA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Gallus gallus 28010 R-GGA-200711 https://reactome.org/PathwayBrowser/#/R-GGA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Gallus gallus 28010 R-GGA-200740 https://reactome.org/PathwayBrowser/#/R-GGA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Gallus gallus 28010 R-GGA-6808487 https://reactome.org/PathwayBrowser/#/R-GGA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Gallus gallus 28010 R-HSA-200661 https://reactome.org/PathwayBrowser/#/R-HSA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG TAS Homo sapiens 28010 R-HSA-200711 https://reactome.org/PathwayBrowser/#/R-HSA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG TAS Homo sapiens 28010 R-HSA-200740 https://reactome.org/PathwayBrowser/#/R-HSA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate TAS Homo sapiens 28010 R-HSA-6808487 https://reactome.org/PathwayBrowser/#/R-HSA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 28010 R-HSA-6808496 https://reactome.org/PathwayBrowser/#/R-HSA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 28010 R-MMU-200661 https://reactome.org/PathwayBrowser/#/R-MMU-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Mus musculus 28010 R-MMU-200711 https://reactome.org/PathwayBrowser/#/R-MMU-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Mus musculus 28010 R-MMU-200740 https://reactome.org/PathwayBrowser/#/R-MMU-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Mus musculus 28010 R-MMU-6808487 https://reactome.org/PathwayBrowser/#/R-MMU-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 28010 R-MMU-6808496 https://reactome.org/PathwayBrowser/#/R-MMU-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 28010 R-PFA-200661 https://reactome.org/PathwayBrowser/#/R-PFA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Plasmodium falciparum 28010 R-PFA-200711 https://reactome.org/PathwayBrowser/#/R-PFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Plasmodium falciparum 28010 R-PFA-200740 https://reactome.org/PathwayBrowser/#/R-PFA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Plasmodium falciparum 28010 R-RNO-200661 https://reactome.org/PathwayBrowser/#/R-RNO-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Rattus norvegicus 28010 R-RNO-200711 https://reactome.org/PathwayBrowser/#/R-RNO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Rattus norvegicus 28010 R-RNO-200740 https://reactome.org/PathwayBrowser/#/R-RNO-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Rattus norvegicus 28010 R-RNO-6808487 https://reactome.org/PathwayBrowser/#/R-RNO-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 28010 R-RNO-6808496 https://reactome.org/PathwayBrowser/#/R-RNO-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 28010 R-SCE-200661 https://reactome.org/PathwayBrowser/#/R-SCE-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Saccharomyces cerevisiae 28010 R-SCE-200711 https://reactome.org/PathwayBrowser/#/R-SCE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Saccharomyces cerevisiae 28010 R-SCE-200740 https://reactome.org/PathwayBrowser/#/R-SCE-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Saccharomyces cerevisiae 28010 R-SPO-200661 https://reactome.org/PathwayBrowser/#/R-SPO-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Schizosaccharomyces pombe 28010 R-SPO-200711 https://reactome.org/PathwayBrowser/#/R-SPO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Schizosaccharomyces pombe 28010 R-SPO-200740 https://reactome.org/PathwayBrowser/#/R-SPO-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Schizosaccharomyces pombe 28010 R-SSC-200661 https://reactome.org/PathwayBrowser/#/R-SSC-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Sus scrofa 28010 R-SSC-200711 https://reactome.org/PathwayBrowser/#/R-SSC-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Sus scrofa 28010 R-SSC-200740 https://reactome.org/PathwayBrowser/#/R-SSC-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Sus scrofa 28010 R-SSC-6808487 https://reactome.org/PathwayBrowser/#/R-SSC-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 28010 R-SSC-6808496 https://reactome.org/PathwayBrowser/#/R-SSC-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 28010 R-XTR-200661 https://reactome.org/PathwayBrowser/#/R-XTR-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Xenopus tropicalis 28010 R-XTR-200711 https://reactome.org/PathwayBrowser/#/R-XTR-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Xenopus tropicalis 28010 R-XTR-200740 https://reactome.org/PathwayBrowser/#/R-XTR-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Xenopus tropicalis 28010 R-XTR-6808487 https://reactome.org/PathwayBrowser/#/R-XTR-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 28010 R-XTR-6808496 https://reactome.org/PathwayBrowser/#/R-XTR-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 28037 R-BTA-1605595 https://reactome.org/PathwayBrowser/#/R-BTA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Bos taurus 28037 R-BTA-1605632 https://reactome.org/PathwayBrowser/#/R-BTA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Bos taurus 28037 R-BTA-1638053 https://reactome.org/PathwayBrowser/#/R-BTA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Bos taurus 28037 R-BTA-2105001 https://reactome.org/PathwayBrowser/#/R-BTA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Bos taurus 28037 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 28037 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 28037 R-BTA-9638075 https://reactome.org/PathwayBrowser/#/R-BTA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Bos taurus 28037 R-BTA-9638078 https://reactome.org/PathwayBrowser/#/R-BTA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Bos taurus 28037 R-BTA-9840833 https://reactome.org/PathwayBrowser/#/R-BTA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Bos taurus 28037 R-BTA-9840884 https://reactome.org/PathwayBrowser/#/R-BTA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Bos taurus 28037 R-CEL-1605595 https://reactome.org/PathwayBrowser/#/R-CEL-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Caenorhabditis elegans 28037 R-CEL-1605632 https://reactome.org/PathwayBrowser/#/R-CEL-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Caenorhabditis elegans 28037 R-CEL-1638053 https://reactome.org/PathwayBrowser/#/R-CEL-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Caenorhabditis elegans 28037 R-CEL-2105001 https://reactome.org/PathwayBrowser/#/R-CEL-2105001 HEXA cleaves the terminal GalNAc from DS IEA Caenorhabditis elegans 28037 R-CEL-9638075 https://reactome.org/PathwayBrowser/#/R-CEL-9638075 HEXB cleaves the terminal GalNAc from DS IEA Caenorhabditis elegans 28037 R-CEL-9638078 https://reactome.org/PathwayBrowser/#/R-CEL-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Caenorhabditis elegans 28037 R-CEL-9840833 https://reactome.org/PathwayBrowser/#/R-CEL-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Caenorhabditis elegans 28037 R-CEL-9840884 https://reactome.org/PathwayBrowser/#/R-CEL-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Caenorhabditis elegans 28037 R-CFA-1605595 https://reactome.org/PathwayBrowser/#/R-CFA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Canis familiaris 28037 R-CFA-1605632 https://reactome.org/PathwayBrowser/#/R-CFA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Canis familiaris 28037 R-CFA-1638053 https://reactome.org/PathwayBrowser/#/R-CFA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Canis familiaris 28037 R-CFA-2105001 https://reactome.org/PathwayBrowser/#/R-CFA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Canis familiaris 28037 R-CFA-9638075 https://reactome.org/PathwayBrowser/#/R-CFA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Canis familiaris 28037 R-CFA-9638078 https://reactome.org/PathwayBrowser/#/R-CFA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Canis familiaris 28037 R-CFA-9840833 https://reactome.org/PathwayBrowser/#/R-CFA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Canis familiaris 28037 R-CFA-9840884 https://reactome.org/PathwayBrowser/#/R-CFA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Canis familiaris 28037 R-DDI-1605632 https://reactome.org/PathwayBrowser/#/R-DDI-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Dictyostelium discoideum 28037 R-DDI-1638053 https://reactome.org/PathwayBrowser/#/R-DDI-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Dictyostelium discoideum 28037 R-DDI-2105001 https://reactome.org/PathwayBrowser/#/R-DDI-2105001 HEXA cleaves the terminal GalNAc from DS IEA Dictyostelium discoideum 28037 R-DDI-9638075 https://reactome.org/PathwayBrowser/#/R-DDI-9638075 HEXB cleaves the terminal GalNAc from DS IEA Dictyostelium discoideum 28037 R-DDI-9638078 https://reactome.org/PathwayBrowser/#/R-DDI-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Dictyostelium discoideum 28037 R-DME-1605632 https://reactome.org/PathwayBrowser/#/R-DME-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Drosophila melanogaster 28037 R-DME-1638053 https://reactome.org/PathwayBrowser/#/R-DME-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Drosophila melanogaster 28037 R-DME-2105001 https://reactome.org/PathwayBrowser/#/R-DME-2105001 HEXA cleaves the terminal GalNAc from DS IEA Drosophila melanogaster 28037 R-DME-9638075 https://reactome.org/PathwayBrowser/#/R-DME-9638075 HEXB cleaves the terminal GalNAc from DS IEA Drosophila melanogaster 28037 R-DME-9638078 https://reactome.org/PathwayBrowser/#/R-DME-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Drosophila melanogaster 28037 R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus 28037 R-GGA-1638053 https://reactome.org/PathwayBrowser/#/R-GGA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Gallus gallus 28037 R-GGA-2105001 https://reactome.org/PathwayBrowser/#/R-GGA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Gallus gallus 28037 R-GGA-9638075 https://reactome.org/PathwayBrowser/#/R-GGA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Gallus gallus 28037 R-GGA-9638078 https://reactome.org/PathwayBrowser/#/R-GGA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Gallus gallus 28037 R-HSA-1605595 https://reactome.org/PathwayBrowser/#/R-HSA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 TAS Homo sapiens 28037 R-HSA-1605632 https://reactome.org/PathwayBrowser/#/R-HSA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE TAS Homo sapiens 28037 R-HSA-1638053 https://reactome.org/PathwayBrowser/#/R-HSA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate TAS Homo sapiens 28037 R-HSA-2105001 https://reactome.org/PathwayBrowser/#/R-HSA-2105001 HEXA cleaves the terminal GalNAc from DS TAS Homo sapiens 28037 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 28037 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 28037 R-HSA-9638075 https://reactome.org/PathwayBrowser/#/R-HSA-9638075 HEXB cleaves the terminal GalNAc from DS TAS Homo sapiens 28037 R-HSA-9638078 https://reactome.org/PathwayBrowser/#/R-HSA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate TAS Homo sapiens 28037 R-HSA-9840833 https://reactome.org/PathwayBrowser/#/R-HSA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer TAS Homo sapiens 28037 R-HSA-9840884 https://reactome.org/PathwayBrowser/#/R-HSA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 TAS Homo sapiens 28037 R-MMU-1605595 https://reactome.org/PathwayBrowser/#/R-MMU-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Mus musculus 28037 R-MMU-1605632 https://reactome.org/PathwayBrowser/#/R-MMU-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Mus musculus 28037 R-MMU-1638053 https://reactome.org/PathwayBrowser/#/R-MMU-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Mus musculus 28037 R-MMU-2105001 https://reactome.org/PathwayBrowser/#/R-MMU-2105001 HEXA cleaves the terminal GalNAc from DS IEA Mus musculus 28037 R-MMU-9638075 https://reactome.org/PathwayBrowser/#/R-MMU-9638075 HEXB cleaves the terminal GalNAc from DS IEA Mus musculus 28037 R-MMU-9638078 https://reactome.org/PathwayBrowser/#/R-MMU-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Mus musculus 28037 R-MMU-9840833 https://reactome.org/PathwayBrowser/#/R-MMU-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Mus musculus 28037 R-MMU-9840884 https://reactome.org/PathwayBrowser/#/R-MMU-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Mus musculus 28037 R-RNO-1605595 https://reactome.org/PathwayBrowser/#/R-RNO-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Rattus norvegicus 28037 R-RNO-1605632 https://reactome.org/PathwayBrowser/#/R-RNO-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Rattus norvegicus 28037 R-RNO-1638053 https://reactome.org/PathwayBrowser/#/R-RNO-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Rattus norvegicus 28037 R-RNO-2105001 https://reactome.org/PathwayBrowser/#/R-RNO-2105001 HEXA cleaves the terminal GalNAc from DS IEA Rattus norvegicus 28037 R-RNO-9638075 https://reactome.org/PathwayBrowser/#/R-RNO-9638075 HEXB cleaves the terminal GalNAc from DS IEA Rattus norvegicus 28037 R-RNO-9638078 https://reactome.org/PathwayBrowser/#/R-RNO-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Rattus norvegicus 28037 R-RNO-9840833 https://reactome.org/PathwayBrowser/#/R-RNO-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Rattus norvegicus 28037 R-RNO-9840884 https://reactome.org/PathwayBrowser/#/R-RNO-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Rattus norvegicus 28037 R-SSC-1605595 https://reactome.org/PathwayBrowser/#/R-SSC-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Sus scrofa 28037 R-SSC-1605632 https://reactome.org/PathwayBrowser/#/R-SSC-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Sus scrofa 28037 R-SSC-1638053 https://reactome.org/PathwayBrowser/#/R-SSC-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Sus scrofa 28037 R-SSC-2105001 https://reactome.org/PathwayBrowser/#/R-SSC-2105001 HEXA cleaves the terminal GalNAc from DS IEA Sus scrofa 28037 R-SSC-9638075 https://reactome.org/PathwayBrowser/#/R-SSC-9638075 HEXB cleaves the terminal GalNAc from DS IEA Sus scrofa 28037 R-SSC-9638078 https://reactome.org/PathwayBrowser/#/R-SSC-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Sus scrofa 28037 R-SSC-9840833 https://reactome.org/PathwayBrowser/#/R-SSC-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Sus scrofa 28037 R-SSC-9840884 https://reactome.org/PathwayBrowser/#/R-SSC-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Sus scrofa 28037 R-XTR-9638075 https://reactome.org/PathwayBrowser/#/R-XTR-9638075 HEXB cleaves the terminal GalNAc from DS IEA Xenopus tropicalis 28037 R-XTR-9638078 https://reactome.org/PathwayBrowser/#/R-XTR-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Xenopus tropicalis 28037 R-XTR-9840833 https://reactome.org/PathwayBrowser/#/R-XTR-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Xenopus tropicalis 28047 R-BTA-192160 https://reactome.org/PathwayBrowser/#/R-BTA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Bos taurus 28047 R-BTA-193393 https://reactome.org/PathwayBrowser/#/R-BTA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Bos taurus 28047 R-CEL-192160 https://reactome.org/PathwayBrowser/#/R-CEL-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Caenorhabditis elegans 28047 R-CFA-193393 https://reactome.org/PathwayBrowser/#/R-CFA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Canis familiaris 28047 R-DDI-192160 https://reactome.org/PathwayBrowser/#/R-DDI-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Dictyostelium discoideum 28047 R-DME-192160 https://reactome.org/PathwayBrowser/#/R-DME-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Drosophila melanogaster 28047 R-HSA-192160 https://reactome.org/PathwayBrowser/#/R-HSA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol TAS Homo sapiens 28047 R-HSA-193393 https://reactome.org/PathwayBrowser/#/R-HSA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol TAS Homo sapiens 28047 R-HSA-193537 https://reactome.org/PathwayBrowser/#/R-HSA-193537 5beta-cholestan-3alpha, 7alpha-diol is translocated from the cytosol to the mitochondrial matrix TAS Homo sapiens 28047 R-MMU-192160 https://reactome.org/PathwayBrowser/#/R-MMU-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Mus musculus 28047 R-MMU-193393 https://reactome.org/PathwayBrowser/#/R-MMU-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Mus musculus 28047 R-RNO-192160 https://reactome.org/PathwayBrowser/#/R-RNO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Rattus norvegicus 28047 R-RNO-193393 https://reactome.org/PathwayBrowser/#/R-RNO-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Rattus norvegicus 28047 R-SCE-192160 https://reactome.org/PathwayBrowser/#/R-SCE-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Saccharomyces cerevisiae 28047 R-SPO-192160 https://reactome.org/PathwayBrowser/#/R-SPO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Schizosaccharomyces pombe 28047 R-SSC-192160 https://reactome.org/PathwayBrowser/#/R-SSC-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Sus scrofa 28047 R-SSC-193393 https://reactome.org/PathwayBrowser/#/R-SSC-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Sus scrofa 28047 R-XTR-192160 https://reactome.org/PathwayBrowser/#/R-XTR-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Xenopus tropicalis 28057 R-BTA-191114 https://reactome.org/PathwayBrowser/#/R-BTA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Bos taurus 28057 R-CEL-191114 https://reactome.org/PathwayBrowser/#/R-CEL-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Caenorhabditis elegans 28057 R-CFA-191114 https://reactome.org/PathwayBrowser/#/R-CFA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Canis familiaris 28057 R-DME-191114 https://reactome.org/PathwayBrowser/#/R-DME-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Drosophila melanogaster 28057 R-DRE-191114 https://reactome.org/PathwayBrowser/#/R-DRE-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Danio rerio 28057 R-GGA-191114 https://reactome.org/PathwayBrowser/#/R-GGA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Gallus gallus 28057 R-HSA-191114 https://reactome.org/PathwayBrowser/#/R-HSA-191114 Digestion of branched starch (amylopectin) by extracellular amylase TAS Homo sapiens 28057 R-MMU-191114 https://reactome.org/PathwayBrowser/#/R-MMU-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Mus musculus 28057 R-RNO-191114 https://reactome.org/PathwayBrowser/#/R-RNO-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Rattus norvegicus 28057 R-SSC-191114 https://reactome.org/PathwayBrowser/#/R-SSC-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Sus scrofa 28057 R-XTR-191114 https://reactome.org/PathwayBrowser/#/R-XTR-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Xenopus tropicalis 28061 R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus 28061 R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus 28061 R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus 28061 R-BTA-1630306 https://reactome.org/PathwayBrowser/#/R-BTA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Bos taurus 28061 R-BTA-2090079 https://reactome.org/PathwayBrowser/#/R-BTA-2090079 GLB1 hydrolyses linker chain(2) IEA Bos taurus 28061 R-BTA-9840795 https://reactome.org/PathwayBrowser/#/R-BTA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Bos taurus 28061 R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 28061 R-CEL-1605624 https://reactome.org/PathwayBrowser/#/R-CEL-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Caenorhabditis elegans 28061 R-CEL-1605736 https://reactome.org/PathwayBrowser/#/R-CEL-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Caenorhabditis elegans 28061 R-CEL-1606312 https://reactome.org/PathwayBrowser/#/R-CEL-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Caenorhabditis elegans 28061 R-CEL-1630306 https://reactome.org/PathwayBrowser/#/R-CEL-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Caenorhabditis elegans 28061 R-CEL-2090079 https://reactome.org/PathwayBrowser/#/R-CEL-2090079 GLB1 hydrolyses linker chain(2) IEA Caenorhabditis elegans 28061 R-CEL-9840795 https://reactome.org/PathwayBrowser/#/R-CEL-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Caenorhabditis elegans 28061 R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 28061 R-CFA-1605624 https://reactome.org/PathwayBrowser/#/R-CFA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Canis familiaris 28061 R-CFA-1605736 https://reactome.org/PathwayBrowser/#/R-CFA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Canis familiaris 28061 R-CFA-1606312 https://reactome.org/PathwayBrowser/#/R-CFA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Canis familiaris 28061 R-CFA-1630306 https://reactome.org/PathwayBrowser/#/R-CFA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Canis familiaris 28061 R-CFA-2090079 https://reactome.org/PathwayBrowser/#/R-CFA-2090079 GLB1 hydrolyses linker chain(2) IEA Canis familiaris 28061 R-CFA-9840795 https://reactome.org/PathwayBrowser/#/R-CFA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Canis familiaris 28061 R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 28061 R-DDI-1605624 https://reactome.org/PathwayBrowser/#/R-DDI-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Dictyostelium discoideum 28061 R-DDI-1605736 https://reactome.org/PathwayBrowser/#/R-DDI-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Dictyostelium discoideum 28061 R-DDI-1606312 https://reactome.org/PathwayBrowser/#/R-DDI-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Dictyostelium discoideum 28061 R-DDI-1630306 https://reactome.org/PathwayBrowser/#/R-DDI-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Dictyostelium discoideum 28061 R-DDI-2090079 https://reactome.org/PathwayBrowser/#/R-DDI-2090079 GLB1 hydrolyses linker chain(2) IEA Dictyostelium discoideum 28061 R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 28061 R-DME-1605624 https://reactome.org/PathwayBrowser/#/R-DME-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Drosophila melanogaster 28061 R-DME-1606312 https://reactome.org/PathwayBrowser/#/R-DME-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Drosophila melanogaster 28061 R-DME-1630306 https://reactome.org/PathwayBrowser/#/R-DME-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Drosophila melanogaster 28061 R-DME-2090079 https://reactome.org/PathwayBrowser/#/R-DME-2090079 GLB1 hydrolyses linker chain(2) IEA Drosophila melanogaster 28061 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus 28061 R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus 28061 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus 28061 R-GGA-1630306 https://reactome.org/PathwayBrowser/#/R-GGA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Gallus gallus 28061 R-GGA-2090079 https://reactome.org/PathwayBrowser/#/R-GGA-2090079 GLB1 hydrolyses linker chain(2) IEA Gallus gallus 28061 R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 28061 R-HSA-1605624 https://reactome.org/PathwayBrowser/#/R-HSA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 TAS Homo sapiens 28061 R-HSA-1605736 https://reactome.org/PathwayBrowser/#/R-HSA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE TAS Homo sapiens 28061 R-HSA-1606312 https://reactome.org/PathwayBrowser/#/R-HSA-1606312 GLB1 hydrolyzes SapB/C:LacCer TAS Homo sapiens 28061 R-HSA-1630306 https://reactome.org/PathwayBrowser/#/R-HSA-1630306 GLB1 hydrolyses a glycosaminoglycan TAS Homo sapiens 28061 R-HSA-2090079 https://reactome.org/PathwayBrowser/#/R-HSA-2090079 GLB1 hydrolyses linker chain(2) TAS Homo sapiens 28061 R-HSA-9840795 https://reactome.org/PathwayBrowser/#/R-HSA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 TAS Homo sapiens 28061 R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 28061 R-MMU-1605624 https://reactome.org/PathwayBrowser/#/R-MMU-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Mus musculus 28061 R-MMU-1605736 https://reactome.org/PathwayBrowser/#/R-MMU-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Mus musculus 28061 R-MMU-1606312 https://reactome.org/PathwayBrowser/#/R-MMU-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Mus musculus 28061 R-MMU-1630306 https://reactome.org/PathwayBrowser/#/R-MMU-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Mus musculus 28061 R-MMU-2090079 https://reactome.org/PathwayBrowser/#/R-MMU-2090079 GLB1 hydrolyses linker chain(2) IEA Mus musculus 28061 R-MMU-9840795 https://reactome.org/PathwayBrowser/#/R-MMU-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Mus musculus 28061 R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 28061 R-RNO-1605624 https://reactome.org/PathwayBrowser/#/R-RNO-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Rattus norvegicus 28061 R-RNO-1605736 https://reactome.org/PathwayBrowser/#/R-RNO-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Rattus norvegicus 28061 R-RNO-1606312 https://reactome.org/PathwayBrowser/#/R-RNO-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Rattus norvegicus 28061 R-RNO-1630306 https://reactome.org/PathwayBrowser/#/R-RNO-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Rattus norvegicus 28061 R-RNO-2090079 https://reactome.org/PathwayBrowser/#/R-RNO-2090079 GLB1 hydrolyses linker chain(2) IEA Rattus norvegicus 28061 R-RNO-9840795 https://reactome.org/PathwayBrowser/#/R-RNO-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Rattus norvegicus 28061 R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 28061 R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa 28061 R-SSC-1605736 https://reactome.org/PathwayBrowser/#/R-SSC-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Sus scrofa 28061 R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa 28061 R-SSC-1630306 https://reactome.org/PathwayBrowser/#/R-SSC-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Sus scrofa 28061 R-SSC-2090079 https://reactome.org/PathwayBrowser/#/R-SSC-2090079 GLB1 hydrolyses linker chain(2) IEA Sus scrofa 28061 R-SSC-9840795 https://reactome.org/PathwayBrowser/#/R-SSC-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Sus scrofa 28061 R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 28061 R-XTR-1605624 https://reactome.org/PathwayBrowser/#/R-XTR-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Xenopus tropicalis 28061 R-XTR-1630306 https://reactome.org/PathwayBrowser/#/R-XTR-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Xenopus tropicalis 28061 R-XTR-2090079 https://reactome.org/PathwayBrowser/#/R-XTR-2090079 GLB1 hydrolyses linker chain(2) IEA Xenopus tropicalis 28061 R-XTR-9840795 https://reactome.org/PathwayBrowser/#/R-XTR-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Xenopus tropicalis 28077 R-BTA-4755524 https://reactome.org/PathwayBrowser/#/R-BTA-4755524 SUMOylation of NR1I2 with SUMO3 IEA Bos taurus 28077 R-DME-4755524 https://reactome.org/PathwayBrowser/#/R-DME-4755524 SUMOylation of NR1I2 with SUMO3 IEA Drosophila melanogaster 28077 R-DRE-4755524 https://reactome.org/PathwayBrowser/#/R-DRE-4755524 SUMOylation of NR1I2 with SUMO3 IEA Danio rerio 28077 R-HSA-4755524 https://reactome.org/PathwayBrowser/#/R-HSA-4755524 SUMOylation of NR1I2 with SUMO3 TAS Homo sapiens 28077 R-HSA-9685655 https://reactome.org/PathwayBrowser/#/R-HSA-9685655 CTSL bind CTSL inhibitors TAS Homo sapiens 28077 R-HSA-9686710 https://reactome.org/PathwayBrowser/#/R-HSA-9686710 Cleavage of S protein into S1:S2 TAS Homo sapiens 28077 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 28077 R-HSA-9697085 https://reactome.org/PathwayBrowser/#/R-HSA-9697085 RNAP transcribes Mtb RNA polyanion TAS Homo sapiens 28077 R-HSA-9697086 https://reactome.org/PathwayBrowser/#/R-HSA-9697086 Rifampicin binds Mtb RNAP TAS Homo sapiens 28077 R-MMU-4755524 https://reactome.org/PathwayBrowser/#/R-MMU-4755524 SUMOylation of NR1I2 with SUMO3 IEA Mus musculus 28077 R-RNO-4755524 https://reactome.org/PathwayBrowser/#/R-RNO-4755524 SUMOylation of NR1I2 with SUMO3 IEA Rattus norvegicus 28077 R-SSC-4755524 https://reactome.org/PathwayBrowser/#/R-SSC-4755524 SUMOylation of NR1I2 with SUMO3 IEA Sus scrofa 28099 R-HSA-2161735 https://reactome.org/PathwayBrowser/#/R-HSA-2161735 PGC2 is isomerised to PGB2 TAS Homo sapiens 28102 R-BTA-188979 https://reactome.org/PathwayBrowser/#/R-BTA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Bos taurus 28102 R-BTA-191114 https://reactome.org/PathwayBrowser/#/R-BTA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Bos taurus 28102 R-CEL-188979 https://reactome.org/PathwayBrowser/#/R-CEL-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Caenorhabditis elegans 28102 R-CEL-191114 https://reactome.org/PathwayBrowser/#/R-CEL-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Caenorhabditis elegans 28102 R-CFA-188979 https://reactome.org/PathwayBrowser/#/R-CFA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Canis familiaris 28102 R-CFA-191114 https://reactome.org/PathwayBrowser/#/R-CFA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Canis familiaris 28102 R-DME-188979 https://reactome.org/PathwayBrowser/#/R-DME-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Drosophila melanogaster 28102 R-DME-191114 https://reactome.org/PathwayBrowser/#/R-DME-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Drosophila melanogaster 28102 R-DRE-188979 https://reactome.org/PathwayBrowser/#/R-DRE-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Danio rerio 28102 R-DRE-191114 https://reactome.org/PathwayBrowser/#/R-DRE-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Danio rerio 28102 R-GGA-188979 https://reactome.org/PathwayBrowser/#/R-GGA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Gallus gallus 28102 R-GGA-191114 https://reactome.org/PathwayBrowser/#/R-GGA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Gallus gallus 28102 R-HSA-188979 https://reactome.org/PathwayBrowser/#/R-HSA-188979 Digestion of linear starch (amylose) by extracellular amylase TAS Homo sapiens 28102 R-HSA-191114 https://reactome.org/PathwayBrowser/#/R-HSA-191114 Digestion of branched starch (amylopectin) by extracellular amylase TAS Homo sapiens 28102 R-MMU-188979 https://reactome.org/PathwayBrowser/#/R-MMU-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Mus musculus 28102 R-MMU-191114 https://reactome.org/PathwayBrowser/#/R-MMU-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Mus musculus 28102 R-RNO-188979 https://reactome.org/PathwayBrowser/#/R-RNO-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Rattus norvegicus 28102 R-RNO-191114 https://reactome.org/PathwayBrowser/#/R-RNO-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Rattus norvegicus 28102 R-SSC-188979 https://reactome.org/PathwayBrowser/#/R-SSC-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Sus scrofa 28102 R-SSC-191114 https://reactome.org/PathwayBrowser/#/R-SSC-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Sus scrofa 28102 R-XTR-188979 https://reactome.org/PathwayBrowser/#/R-XTR-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Xenopus tropicalis 28102 R-XTR-191114 https://reactome.org/PathwayBrowser/#/R-XTR-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Xenopus tropicalis 28113 R-BTA-9755937 https://reactome.org/PathwayBrowser/#/R-BTA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Bos taurus 28113 R-CEL-9755937 https://reactome.org/PathwayBrowser/#/R-CEL-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Caenorhabditis elegans 28113 R-CFA-9755937 https://reactome.org/PathwayBrowser/#/R-CFA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Canis familiaris 28113 R-DRE-9755937 https://reactome.org/PathwayBrowser/#/R-DRE-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Danio rerio 28113 R-GGA-9755937 https://reactome.org/PathwayBrowser/#/R-GGA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Gallus gallus 28113 R-HSA-9755937 https://reactome.org/PathwayBrowser/#/R-HSA-9755937 DHCR24 reduces LAN to 24,25-dhLAN TAS Homo sapiens 28113 R-MMU-9755937 https://reactome.org/PathwayBrowser/#/R-MMU-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Mus musculus 28113 R-RNO-9755937 https://reactome.org/PathwayBrowser/#/R-RNO-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Rattus norvegicus 28113 R-SSC-9755937 https://reactome.org/PathwayBrowser/#/R-SSC-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Sus scrofa 28113 R-XTR-9755937 https://reactome.org/PathwayBrowser/#/R-XTR-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Xenopus tropicalis 28115 R-BTA-174374 https://reactome.org/PathwayBrowser/#/R-BTA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Bos taurus 28115 R-BTA-3149518 https://reactome.org/PathwayBrowser/#/R-BTA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Bos taurus 28115 R-BTA-3149539 https://reactome.org/PathwayBrowser/#/R-BTA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Bos taurus 28115 R-CEL-174374 https://reactome.org/PathwayBrowser/#/R-CEL-174374 MTR transfers CH3 from MeCbl to HCYS IEA Caenorhabditis elegans 28115 R-CEL-3149518 https://reactome.org/PathwayBrowser/#/R-CEL-3149518 MTRR reduces cob(II)alamin to meCbl IEA Caenorhabditis elegans 28115 R-CEL-3149539 https://reactome.org/PathwayBrowser/#/R-CEL-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Caenorhabditis elegans 28115 R-CFA-174374 https://reactome.org/PathwayBrowser/#/R-CFA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Canis familiaris 28115 R-CFA-3149518 https://reactome.org/PathwayBrowser/#/R-CFA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Canis familiaris 28115 R-CFA-3149539 https://reactome.org/PathwayBrowser/#/R-CFA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Canis familiaris 28115 R-DDI-174374 https://reactome.org/PathwayBrowser/#/R-DDI-174374 MTR transfers CH3 from MeCbl to HCYS IEA Dictyostelium discoideum 28115 R-DDI-3149518 https://reactome.org/PathwayBrowser/#/R-DDI-3149518 MTRR reduces cob(II)alamin to meCbl IEA Dictyostelium discoideum 28115 R-DDI-3149539 https://reactome.org/PathwayBrowser/#/R-DDI-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Dictyostelium discoideum 28115 R-GGA-174374 https://reactome.org/PathwayBrowser/#/R-GGA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Gallus gallus 28115 R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus 28115 R-GGA-3149539 https://reactome.org/PathwayBrowser/#/R-GGA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Gallus gallus 28115 R-HSA-174374 https://reactome.org/PathwayBrowser/#/R-HSA-174374 MTR transfers CH3 from MeCbl to HCYS TAS Homo sapiens 28115 R-HSA-3149518 https://reactome.org/PathwayBrowser/#/R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl TAS Homo sapiens 28115 R-HSA-3149539 https://reactome.org/PathwayBrowser/#/R-HSA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin TAS Homo sapiens 28115 R-HSA-3322140 https://reactome.org/PathwayBrowser/#/R-HSA-3322140 Defective MTR does not transfer CH3 group from MeCbl to HCYS TAS Homo sapiens 28115 R-MMU-174374 https://reactome.org/PathwayBrowser/#/R-MMU-174374 MTR transfers CH3 from MeCbl to HCYS IEA Mus musculus 28115 R-MMU-3149518 https://reactome.org/PathwayBrowser/#/R-MMU-3149518 MTRR reduces cob(II)alamin to meCbl IEA Mus musculus 28115 R-MMU-3149539 https://reactome.org/PathwayBrowser/#/R-MMU-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Mus musculus 28115 R-RNO-174374 https://reactome.org/PathwayBrowser/#/R-RNO-174374 MTR transfers CH3 from MeCbl to HCYS IEA Rattus norvegicus 28115 R-RNO-3149518 https://reactome.org/PathwayBrowser/#/R-RNO-3149518 MTRR reduces cob(II)alamin to meCbl IEA Rattus norvegicus 28115 R-RNO-3149539 https://reactome.org/PathwayBrowser/#/R-RNO-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Rattus norvegicus 28115 R-SSC-174374 https://reactome.org/PathwayBrowser/#/R-SSC-174374 MTR transfers CH3 from MeCbl to HCYS IEA Sus scrofa 28115 R-SSC-3149518 https://reactome.org/PathwayBrowser/#/R-SSC-3149518 MTRR reduces cob(II)alamin to meCbl IEA Sus scrofa 28115 R-SSC-3149539 https://reactome.org/PathwayBrowser/#/R-SSC-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Sus scrofa 28119 R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 28119 R-BTA-5692283 https://reactome.org/PathwayBrowser/#/R-BTA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Bos taurus 28119 R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 28119 R-BTA-8936849 https://reactome.org/PathwayBrowser/#/R-BTA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Bos taurus 28119 R-BTA-8937169 https://reactome.org/PathwayBrowser/#/R-BTA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Bos taurus 28119 R-BTA-8937177 https://reactome.org/PathwayBrowser/#/R-BTA-8937177 AHR:TCDD binds ARNT IEA Bos taurus 28119 R-BTA-8937191 https://reactome.org/PathwayBrowser/#/R-BTA-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Bos taurus 28119 R-CEL-8936849 https://reactome.org/PathwayBrowser/#/R-CEL-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Caenorhabditis elegans 28119 R-CEL-8937169 https://reactome.org/PathwayBrowser/#/R-CEL-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Caenorhabditis elegans 28119 R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 28119 R-CFA-5692283 https://reactome.org/PathwayBrowser/#/R-CFA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Canis familiaris 28119 R-CFA-8936849 https://reactome.org/PathwayBrowser/#/R-CFA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Canis familiaris 28119 R-CFA-8937169 https://reactome.org/PathwayBrowser/#/R-CFA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Canis familiaris 28119 R-CFA-8937177 https://reactome.org/PathwayBrowser/#/R-CFA-8937177 AHR:TCDD binds ARNT IEA Canis familiaris 28119 R-DDI-8936849 https://reactome.org/PathwayBrowser/#/R-DDI-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Dictyostelium discoideum 28119 R-DDI-8937169 https://reactome.org/PathwayBrowser/#/R-DDI-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Dictyostelium discoideum 28119 R-DME-5692283 https://reactome.org/PathwayBrowser/#/R-DME-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Drosophila melanogaster 28119 R-DME-8936849 https://reactome.org/PathwayBrowser/#/R-DME-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Drosophila melanogaster 28119 R-DME-8937169 https://reactome.org/PathwayBrowser/#/R-DME-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Drosophila melanogaster 28119 R-DME-8937177 https://reactome.org/PathwayBrowser/#/R-DME-8937177 AHR:TCDD binds ARNT IEA Drosophila melanogaster 28119 R-DME-8937191 https://reactome.org/PathwayBrowser/#/R-DME-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Drosophila melanogaster 28119 R-DRE-8936849 https://reactome.org/PathwayBrowser/#/R-DRE-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Danio rerio 28119 R-DRE-8937169 https://reactome.org/PathwayBrowser/#/R-DRE-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Danio rerio 28119 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 28119 R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus 28119 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 28119 R-GGA-8936849 https://reactome.org/PathwayBrowser/#/R-GGA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Gallus gallus 28119 R-GGA-8937169 https://reactome.org/PathwayBrowser/#/R-GGA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Gallus gallus 28119 R-GGA-8937177 https://reactome.org/PathwayBrowser/#/R-GGA-8937177 AHR:TCDD binds ARNT IEA Gallus gallus 28119 R-GGA-8937191 https://reactome.org/PathwayBrowser/#/R-GGA-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Gallus gallus 28119 R-HSA-1989764 https://reactome.org/PathwayBrowser/#/R-HSA-1989764 Expression of CYP1A1 TAS Homo sapiens 28119 R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 28119 R-HSA-5692283 https://reactome.org/PathwayBrowser/#/R-HSA-5692283 ALD3A1 oxidises 4HPCP to CXPA TAS Homo sapiens 28119 R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 28119 R-HSA-8936849 https://reactome.org/PathwayBrowser/#/R-HSA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD TAS Homo sapiens 28119 R-HSA-8937169 https://reactome.org/PathwayBrowser/#/R-HSA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm TAS Homo sapiens 28119 R-HSA-8937177 https://reactome.org/PathwayBrowser/#/R-HSA-8937177 AHR:TCDD binds ARNT TAS Homo sapiens 28119 R-HSA-8937191 https://reactome.org/PathwayBrowser/#/R-HSA-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates TAS Homo sapiens 28119 R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 28119 R-MMU-5692283 https://reactome.org/PathwayBrowser/#/R-MMU-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Mus musculus 28119 R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 28119 R-MMU-8936849 https://reactome.org/PathwayBrowser/#/R-MMU-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Mus musculus 28119 R-MMU-8937169 https://reactome.org/PathwayBrowser/#/R-MMU-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Mus musculus 28119 R-MMU-8937177 https://reactome.org/PathwayBrowser/#/R-MMU-8937177 AHR:TCDD binds ARNT IEA Mus musculus 28119 R-MMU-8937191 https://reactome.org/PathwayBrowser/#/R-MMU-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Mus musculus 28119 R-PFA-8936849 https://reactome.org/PathwayBrowser/#/R-PFA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Plasmodium falciparum 28119 R-PFA-8937169 https://reactome.org/PathwayBrowser/#/R-PFA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Plasmodium falciparum 28119 R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 28119 R-RNO-5692283 https://reactome.org/PathwayBrowser/#/R-RNO-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Rattus norvegicus 28119 R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 28119 R-RNO-8936849 https://reactome.org/PathwayBrowser/#/R-RNO-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Rattus norvegicus 28119 R-RNO-8937169 https://reactome.org/PathwayBrowser/#/R-RNO-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Rattus norvegicus 28119 R-RNO-8937177 https://reactome.org/PathwayBrowser/#/R-RNO-8937177 AHR:TCDD binds ARNT IEA Rattus norvegicus 28119 R-RNO-8937191 https://reactome.org/PathwayBrowser/#/R-RNO-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Rattus norvegicus 28119 R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 28119 R-SSC-5692283 https://reactome.org/PathwayBrowser/#/R-SSC-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Sus scrofa 28119 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 28119 R-SSC-8936849 https://reactome.org/PathwayBrowser/#/R-SSC-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Sus scrofa 28119 R-SSC-8937169 https://reactome.org/PathwayBrowser/#/R-SSC-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Sus scrofa 28119 R-SSC-8937177 https://reactome.org/PathwayBrowser/#/R-SSC-8937177 AHR:TCDD binds ARNT IEA Sus scrofa 28119 R-SSC-8937191 https://reactome.org/PathwayBrowser/#/R-SSC-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Sus scrofa 28119 R-XTR-8936849 https://reactome.org/PathwayBrowser/#/R-XTR-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Xenopus tropicalis 28119 R-XTR-8937169 https://reactome.org/PathwayBrowser/#/R-XTR-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Xenopus tropicalis 28119 R-XTR-8937177 https://reactome.org/PathwayBrowser/#/R-XTR-8937177 AHR:TCDD binds ARNT IEA Xenopus tropicalis 28119 R-XTR-8937191 https://reactome.org/PathwayBrowser/#/R-XTR-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Xenopus tropicalis 28130 R-HSA-2161563 https://reactome.org/PathwayBrowser/#/R-HSA-2161563 PGJ2 is isomerised to delta12-PGJ2 TAS Homo sapiens 28130 R-HSA-2161588 https://reactome.org/PathwayBrowser/#/R-HSA-2161588 Delta12-PGJ2 is dehydrated to 15d-PGJ2 TAS Homo sapiens 28158 R-HSA-2161619 https://reactome.org/PathwayBrowser/#/R-HSA-2161619 PGI2 is hydrolysed to 6k-PGF1a TAS Homo sapiens 28164 R-CFA-2247510 https://reactome.org/PathwayBrowser/#/R-CFA-2247510 MARCO:ligand is endocytosed IEA Canis familiaris 28164 R-HSA-2173781 https://reactome.org/PathwayBrowser/#/R-HSA-2173781 MARCO (SCARA2) binds ligands IEA Homo sapiens 28164 R-HSA-2247510 https://reactome.org/PathwayBrowser/#/R-HSA-2247510 MARCO:ligand is endocytosed TAS Homo sapiens 28164 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 28164 R-MMU-2247510 https://reactome.org/PathwayBrowser/#/R-MMU-2247510 MARCO:ligand is endocytosed IEA Mus musculus 28164 R-RNO-2247510 https://reactome.org/PathwayBrowser/#/R-RNO-2247510 MARCO:ligand is endocytosed IEA Rattus norvegicus 28179 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 28179 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 28179 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 28179 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 28179 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 28179 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 28179 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 28179 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 28179 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 28179 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 28181 R-BTA-9824732 https://reactome.org/PathwayBrowser/#/R-BTA-9824732 G or G analog binds C-ter TLR7 dimer IEA Bos taurus 28181 R-CFA-9824732 https://reactome.org/PathwayBrowser/#/R-CFA-9824732 G or G analog binds C-ter TLR7 dimer IEA Canis familiaris 28181 R-GGA-9824732 https://reactome.org/PathwayBrowser/#/R-GGA-9824732 G or G analog binds C-ter TLR7 dimer IEA Gallus gallus 28181 R-HSA-9824732 https://reactome.org/PathwayBrowser/#/R-HSA-9824732 G or G analog binds C-ter TLR7 dimer TAS Homo sapiens 28181 R-HSA-9824849 https://reactome.org/PathwayBrowser/#/R-HSA-9824849 G or G analog binds C-ter TLR7 GoF variant TAS Homo sapiens 28181 R-MMU-9824732 https://reactome.org/PathwayBrowser/#/R-MMU-9824732 G or G analog binds C-ter TLR7 dimer IEA Mus musculus 28181 R-RNO-9824732 https://reactome.org/PathwayBrowser/#/R-RNO-9824732 G or G analog binds C-ter TLR7 dimer IEA Rattus norvegicus 28181 R-SSC-9824732 https://reactome.org/PathwayBrowser/#/R-SSC-9824732 G or G analog binds C-ter TLR7 dimer IEA Sus scrofa 28181 R-XTR-9824732 https://reactome.org/PathwayBrowser/#/R-XTR-9824732 G or G analog binds C-ter TLR7 dimer IEA Xenopus tropicalis 28189 R-BTA-5659861 https://reactome.org/PathwayBrowser/#/R-BTA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Bos taurus 28189 R-CEL-5659861 https://reactome.org/PathwayBrowser/#/R-CEL-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 28189 R-CFA-5659861 https://reactome.org/PathwayBrowser/#/R-CFA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Canis familiaris 28189 R-DDI-5659861 https://reactome.org/PathwayBrowser/#/R-DDI-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 28189 R-GGA-5659861 https://reactome.org/PathwayBrowser/#/R-GGA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus 28189 R-HSA-5659861 https://reactome.org/PathwayBrowser/#/R-HSA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) TAS Homo sapiens 28189 R-HSA-5659879 https://reactome.org/PathwayBrowser/#/R-HSA-5659879 Defective SI does not hydrolyze iMal IEA Homo sapiens 28189 R-MMU-5659861 https://reactome.org/PathwayBrowser/#/R-MMU-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Mus musculus 28189 R-RNO-5659861 https://reactome.org/PathwayBrowser/#/R-RNO-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 28189 R-SPO-5659861 https://reactome.org/PathwayBrowser/#/R-SPO-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 28189 R-SSC-5659861 https://reactome.org/PathwayBrowser/#/R-SSC-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Sus scrofa 28195 R-GGA-421508 https://reactome.org/PathwayBrowser/#/R-GGA-421508 Synthesis of ALAS1 nascent polypeptide TAS Gallus gallus 28199 R-ECO-1222667 https://reactome.org/PathwayBrowser/#/R-ECO-1222667 Iron is reduced and separates from enterobactin TAS Escherichia coli 28209 R-HSA-2161776 https://reactome.org/PathwayBrowser/#/R-HSA-2161776 5S-HETE is oxidised to 5-oxoETE by 5-HEDH TAS Homo sapiens 28209 R-HSA-2161946 https://reactome.org/PathwayBrowser/#/R-HSA-2161946 5S-HpETE is reduced to 5S-HETE by GPX1/2/4 IEA Homo sapiens 28209 R-OCU-2161896 https://reactome.org/PathwayBrowser/#/R-OCU-2161896 5S-HpETE is reduced to 5S-HETE by GPX1 TAS Oryctolagus cuniculus 28229 R-BTA-8959781 https://reactome.org/PathwayBrowser/#/R-BTA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Bos taurus 28229 R-CEL-8959781 https://reactome.org/PathwayBrowser/#/R-CEL-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Caenorhabditis elegans 28229 R-CFA-8959781 https://reactome.org/PathwayBrowser/#/R-CFA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Canis familiaris 28229 R-DME-8959781 https://reactome.org/PathwayBrowser/#/R-DME-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Drosophila melanogaster 28229 R-DRE-8959781 https://reactome.org/PathwayBrowser/#/R-DRE-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Danio rerio 28229 R-GGA-8959781 https://reactome.org/PathwayBrowser/#/R-GGA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Gallus gallus 28229 R-HSA-8959781 https://reactome.org/PathwayBrowser/#/R-HSA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix TAS Homo sapiens 28229 R-MMU-8959781 https://reactome.org/PathwayBrowser/#/R-MMU-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Mus musculus 28229 R-RNO-8959781 https://reactome.org/PathwayBrowser/#/R-RNO-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Rattus norvegicus 28229 R-XTR-8959781 https://reactome.org/PathwayBrowser/#/R-XTR-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Xenopus tropicalis 28235 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 28235 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 28235 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 28235 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 28235 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 28235 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 28235 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 28235 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 28235 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 28240 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 28240 R-BTA-9011543 https://reactome.org/PathwayBrowser/#/R-BTA-9011543 DCA binds PDK2 IEA Bos taurus 28240 R-BTA-9011595 https://reactome.org/PathwayBrowser/#/R-BTA-9011595 GSTZ1 dimer dehalogenates DCA IEA Bos taurus 28240 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 28240 R-CEL-9011543 https://reactome.org/PathwayBrowser/#/R-CEL-9011543 DCA binds PDK2 IEA Caenorhabditis elegans 28240 R-CEL-9011595 https://reactome.org/PathwayBrowser/#/R-CEL-9011595 GSTZ1 dimer dehalogenates DCA IEA Caenorhabditis elegans 28240 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 28240 R-CFA-9011543 https://reactome.org/PathwayBrowser/#/R-CFA-9011543 DCA binds PDK2 IEA Canis familiaris 28240 R-CFA-9011595 https://reactome.org/PathwayBrowser/#/R-CFA-9011595 GSTZ1 dimer dehalogenates DCA IEA Canis familiaris 28240 R-DDI-9011595 https://reactome.org/PathwayBrowser/#/R-DDI-9011595 GSTZ1 dimer dehalogenates DCA IEA Dictyostelium discoideum 28240 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 28240 R-DME-9011543 https://reactome.org/PathwayBrowser/#/R-DME-9011543 DCA binds PDK2 IEA Drosophila melanogaster 28240 R-DME-9011595 https://reactome.org/PathwayBrowser/#/R-DME-9011595 GSTZ1 dimer dehalogenates DCA IEA Drosophila melanogaster 28240 R-DRE-9011543 https://reactome.org/PathwayBrowser/#/R-DRE-9011543 DCA binds PDK2 IEA Danio rerio 28240 R-DRE-9011595 https://reactome.org/PathwayBrowser/#/R-DRE-9011595 GSTZ1 dimer dehalogenates DCA IEA Danio rerio 28240 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 28240 R-GGA-9011543 https://reactome.org/PathwayBrowser/#/R-GGA-9011543 DCA binds PDK2 IEA Gallus gallus 28240 R-GGA-9011595 https://reactome.org/PathwayBrowser/#/R-GGA-9011595 GSTZ1 dimer dehalogenates DCA IEA Gallus gallus 28240 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 28240 R-HSA-9011543 https://reactome.org/PathwayBrowser/#/R-HSA-9011543 DCA binds PDK2 TAS Homo sapiens 28240 R-HSA-9011595 https://reactome.org/PathwayBrowser/#/R-HSA-9011595 GSTZ1 dimer dehalogenates DCA TAS Homo sapiens 28240 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 28240 R-MMU-9011543 https://reactome.org/PathwayBrowser/#/R-MMU-9011543 DCA binds PDK2 IEA Mus musculus 28240 R-MMU-9011595 https://reactome.org/PathwayBrowser/#/R-MMU-9011595 GSTZ1 dimer dehalogenates DCA IEA Mus musculus 28240 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 28240 R-RNO-9011543 https://reactome.org/PathwayBrowser/#/R-RNO-9011543 DCA binds PDK2 IEA Rattus norvegicus 28240 R-RNO-9011595 https://reactome.org/PathwayBrowser/#/R-RNO-9011595 GSTZ1 dimer dehalogenates DCA IEA Rattus norvegicus 28240 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 28240 R-SPO-9011543 https://reactome.org/PathwayBrowser/#/R-SPO-9011543 DCA binds PDK2 IEA Schizosaccharomyces pombe 28240 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 28240 R-SSC-9011543 https://reactome.org/PathwayBrowser/#/R-SSC-9011543 DCA binds PDK2 IEA Sus scrofa 28240 R-SSC-9011595 https://reactome.org/PathwayBrowser/#/R-SSC-9011595 GSTZ1 dimer dehalogenates DCA IEA Sus scrofa 28240 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 28240 R-XTR-9011543 https://reactome.org/PathwayBrowser/#/R-XTR-9011543 DCA binds PDK2 IEA Xenopus tropicalis 28240 R-XTR-9011595 https://reactome.org/PathwayBrowser/#/R-XTR-9011595 GSTZ1 dimer dehalogenates DCA IEA Xenopus tropicalis 28241 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 28241 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 28241 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 28241 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 28241 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 28241 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 28241 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 28241 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 28241 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 28241 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 28241 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 28241 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 28241 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 28241 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 28241 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 28241 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 28241 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 28241 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 28241 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 28241 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 28241 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 28241 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 28241 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 28241 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 28241 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 28241 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 28241 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 28241 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 28241 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 28241 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 28241 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 28241 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 28241 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 28241 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 28241 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 28241 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 28241 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 28241 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 28241 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 28241 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 28241 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 28241 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 2825 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 2825 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2825 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2825 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2825 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 2825 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 2825 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2825 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2825 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2825 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 2825 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 2825 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2825 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 2825 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 2825 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2825 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 2825 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2825 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 2825 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 2825 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2825 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2825 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2825 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 2825 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 2825 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 2825 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 2825 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2825 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2825 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2825 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 2825 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 2825 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2825 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 2825 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 2825 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2825 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2825 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2825 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 2825 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 2825 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2825 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 2825 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 28255 R-BTA-4085217 https://reactome.org/PathwayBrowser/#/R-BTA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Bos taurus 28255 R-BTA-6803761 https://reactome.org/PathwayBrowser/#/R-BTA-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Bos taurus 28255 R-CFA-4085217 https://reactome.org/PathwayBrowser/#/R-CFA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Canis familiaris 28255 R-DRE-4085217 https://reactome.org/PathwayBrowser/#/R-DRE-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Danio rerio 28255 R-GGA-4085217 https://reactome.org/PathwayBrowser/#/R-GGA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Gallus gallus 28255 R-HSA-4085217 https://reactome.org/PathwayBrowser/#/R-HSA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate TAS Homo sapiens 28255 R-HSA-6803761 https://reactome.org/PathwayBrowser/#/R-HSA-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc TAS Homo sapiens 28255 R-MMU-4085217 https://reactome.org/PathwayBrowser/#/R-MMU-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Mus musculus 28255 R-MMU-6803761 https://reactome.org/PathwayBrowser/#/R-MMU-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Mus musculus 28255 R-RNO-4085217 https://reactome.org/PathwayBrowser/#/R-RNO-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Rattus norvegicus 28255 R-RNO-6803761 https://reactome.org/PathwayBrowser/#/R-RNO-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Rattus norvegicus 28255 R-SSC-4085217 https://reactome.org/PathwayBrowser/#/R-SSC-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Sus scrofa 28255 R-SSC-6803761 https://reactome.org/PathwayBrowser/#/R-SSC-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Sus scrofa 28255 R-XTR-4085217 https://reactome.org/PathwayBrowser/#/R-XTR-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Xenopus tropicalis 28255 R-XTR-6803761 https://reactome.org/PathwayBrowser/#/R-XTR-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc IEA Xenopus tropicalis 28259 R-BTA-70870 https://reactome.org/PathwayBrowser/#/R-BTA-70870 ECHS1 hydrates methacrylyl-CoA IEA Bos taurus 28259 R-BTA-70881 https://reactome.org/PathwayBrowser/#/R-BTA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Bos taurus 28259 R-CEL-70870 https://reactome.org/PathwayBrowser/#/R-CEL-70870 ECHS1 hydrates methacrylyl-CoA IEA Caenorhabditis elegans 28259 R-CEL-70881 https://reactome.org/PathwayBrowser/#/R-CEL-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Caenorhabditis elegans 28259 R-CFA-70870 https://reactome.org/PathwayBrowser/#/R-CFA-70870 ECHS1 hydrates methacrylyl-CoA IEA Canis familiaris 28259 R-CFA-70881 https://reactome.org/PathwayBrowser/#/R-CFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Canis familiaris 28259 R-DDI-70870 https://reactome.org/PathwayBrowser/#/R-DDI-70870 ECHS1 hydrates methacrylyl-CoA IEA Dictyostelium discoideum 28259 R-DDI-70881 https://reactome.org/PathwayBrowser/#/R-DDI-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Dictyostelium discoideum 28259 R-DME-70870 https://reactome.org/PathwayBrowser/#/R-DME-70870 ECHS1 hydrates methacrylyl-CoA IEA Drosophila melanogaster 28259 R-DME-70881 https://reactome.org/PathwayBrowser/#/R-DME-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Drosophila melanogaster 28259 R-DRE-70881 https://reactome.org/PathwayBrowser/#/R-DRE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Danio rerio 28259 R-GGA-70881 https://reactome.org/PathwayBrowser/#/R-GGA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Gallus gallus 28259 R-HSA-70870 https://reactome.org/PathwayBrowser/#/R-HSA-70870 ECHS1 hydrates methacrylyl-CoA TAS Homo sapiens 28259 R-HSA-70881 https://reactome.org/PathwayBrowser/#/R-HSA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA TAS Homo sapiens 28259 R-MMU-70870 https://reactome.org/PathwayBrowser/#/R-MMU-70870 ECHS1 hydrates methacrylyl-CoA IEA Mus musculus 28259 R-MMU-70881 https://reactome.org/PathwayBrowser/#/R-MMU-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Mus musculus 28259 R-PFA-70881 https://reactome.org/PathwayBrowser/#/R-PFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Plasmodium falciparum 28259 R-RNO-70870 https://reactome.org/PathwayBrowser/#/R-RNO-70870 ECHS1 hydrates methacrylyl-CoA IEA Rattus norvegicus 28259 R-RNO-70881 https://reactome.org/PathwayBrowser/#/R-RNO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Rattus norvegicus 28259 R-SCE-70881 https://reactome.org/PathwayBrowser/#/R-SCE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Saccharomyces cerevisiae 28259 R-SPO-70881 https://reactome.org/PathwayBrowser/#/R-SPO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Schizosaccharomyces pombe 28259 R-SSC-70870 https://reactome.org/PathwayBrowser/#/R-SSC-70870 ECHS1 hydrates methacrylyl-CoA IEA Sus scrofa 28259 R-SSC-70881 https://reactome.org/PathwayBrowser/#/R-SSC-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Sus scrofa 28259 R-XTR-70870 https://reactome.org/PathwayBrowser/#/R-XTR-70870 ECHS1 hydrates methacrylyl-CoA IEA Xenopus tropicalis 28264 R-BTA-77329 https://reactome.org/PathwayBrowser/#/R-BTA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Bos taurus 28264 R-BTA-77331 https://reactome.org/PathwayBrowser/#/R-BTA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Bos taurus 28264 R-CEL-77329 https://reactome.org/PathwayBrowser/#/R-CEL-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Caenorhabditis elegans 28264 R-CEL-77331 https://reactome.org/PathwayBrowser/#/R-CEL-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Caenorhabditis elegans 28264 R-CFA-77329 https://reactome.org/PathwayBrowser/#/R-CFA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Canis familiaris 28264 R-CFA-77331 https://reactome.org/PathwayBrowser/#/R-CFA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Canis familiaris 28264 R-DME-77329 https://reactome.org/PathwayBrowser/#/R-DME-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Drosophila melanogaster 28264 R-DRE-77329 https://reactome.org/PathwayBrowser/#/R-DRE-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Danio rerio 28264 R-DRE-77331 https://reactome.org/PathwayBrowser/#/R-DRE-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Danio rerio 28264 R-GGA-77329 https://reactome.org/PathwayBrowser/#/R-GGA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Gallus gallus 28264 R-GGA-77331 https://reactome.org/PathwayBrowser/#/R-GGA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Gallus gallus 28264 R-HSA-77329 https://reactome.org/PathwayBrowser/#/R-HSA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA TAS Homo sapiens 28264 R-HSA-77331 https://reactome.org/PathwayBrowser/#/R-HSA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H TAS Homo sapiens 28264 R-MMU-77329 https://reactome.org/PathwayBrowser/#/R-MMU-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Mus musculus 28264 R-MMU-77331 https://reactome.org/PathwayBrowser/#/R-MMU-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Mus musculus 28264 R-RNO-77329 https://reactome.org/PathwayBrowser/#/R-RNO-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Rattus norvegicus 28264 R-RNO-77331 https://reactome.org/PathwayBrowser/#/R-RNO-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Rattus norvegicus 28264 R-SSC-77329 https://reactome.org/PathwayBrowser/#/R-SSC-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Sus scrofa 28264 R-SSC-77331 https://reactome.org/PathwayBrowser/#/R-SSC-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Sus scrofa 28264 R-XTR-77329 https://reactome.org/PathwayBrowser/#/R-XTR-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Xenopus tropicalis 28264 R-XTR-77331 https://reactome.org/PathwayBrowser/#/R-XTR-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Xenopus tropicalis 28273 R-BTA-4084976 https://reactome.org/PathwayBrowser/#/R-BTA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Bos taurus 28273 R-BTA-4085028 https://reactome.org/PathwayBrowser/#/R-BTA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Bos taurus 28273 R-CFA-4084976 https://reactome.org/PathwayBrowser/#/R-CFA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Canis familiaris 28273 R-CFA-4085028 https://reactome.org/PathwayBrowser/#/R-CFA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Canis familiaris 28273 R-DME-4084976 https://reactome.org/PathwayBrowser/#/R-DME-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Drosophila melanogaster 28273 R-DRE-4084976 https://reactome.org/PathwayBrowser/#/R-DRE-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Danio rerio 28273 R-DRE-4085028 https://reactome.org/PathwayBrowser/#/R-DRE-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Danio rerio 28273 R-GGA-4084976 https://reactome.org/PathwayBrowser/#/R-GGA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Gallus gallus 28273 R-GGA-4085028 https://reactome.org/PathwayBrowser/#/R-GGA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Gallus gallus 28273 R-HSA-4084976 https://reactome.org/PathwayBrowser/#/R-HSA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P TAS Homo sapiens 28273 R-HSA-4085028 https://reactome.org/PathwayBrowser/#/R-HSA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P TAS Homo sapiens 28273 R-MMU-4084976 https://reactome.org/PathwayBrowser/#/R-MMU-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Mus musculus 28273 R-MMU-4085028 https://reactome.org/PathwayBrowser/#/R-MMU-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Mus musculus 28273 R-RNO-4084976 https://reactome.org/PathwayBrowser/#/R-RNO-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Rattus norvegicus 28273 R-RNO-4085028 https://reactome.org/PathwayBrowser/#/R-RNO-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Rattus norvegicus 28273 R-SSC-4084976 https://reactome.org/PathwayBrowser/#/R-SSC-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Sus scrofa 28273 R-SSC-4085028 https://reactome.org/PathwayBrowser/#/R-SSC-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Sus scrofa 28273 R-XTR-4084976 https://reactome.org/PathwayBrowser/#/R-XTR-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Xenopus tropicalis 28273 R-XTR-4085028 https://reactome.org/PathwayBrowser/#/R-XTR-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Xenopus tropicalis 28276 R-BTA-77323 https://reactome.org/PathwayBrowser/#/R-BTA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Bos taurus 28276 R-BTA-77325 https://reactome.org/PathwayBrowser/#/R-BTA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Bos taurus 28276 R-CEL-77323 https://reactome.org/PathwayBrowser/#/R-CEL-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Caenorhabditis elegans 28276 R-CEL-77325 https://reactome.org/PathwayBrowser/#/R-CEL-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Caenorhabditis elegans 28276 R-CFA-77323 https://reactome.org/PathwayBrowser/#/R-CFA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Canis familiaris 28276 R-CFA-77325 https://reactome.org/PathwayBrowser/#/R-CFA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Canis familiaris 28276 R-DDI-77325 https://reactome.org/PathwayBrowser/#/R-DDI-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Dictyostelium discoideum 28276 R-DME-77325 https://reactome.org/PathwayBrowser/#/R-DME-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Drosophila melanogaster 28276 R-DRE-77323 https://reactome.org/PathwayBrowser/#/R-DRE-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Danio rerio 28276 R-GGA-77323 https://reactome.org/PathwayBrowser/#/R-GGA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Gallus gallus 28276 R-HSA-77323 https://reactome.org/PathwayBrowser/#/R-HSA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H TAS Homo sapiens 28276 R-HSA-77325 https://reactome.org/PathwayBrowser/#/R-HSA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA TAS Homo sapiens 28276 R-MMU-77323 https://reactome.org/PathwayBrowser/#/R-MMU-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Mus musculus 28276 R-MMU-77325 https://reactome.org/PathwayBrowser/#/R-MMU-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Mus musculus 28276 R-RNO-77323 https://reactome.org/PathwayBrowser/#/R-RNO-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Rattus norvegicus 28276 R-RNO-77325 https://reactome.org/PathwayBrowser/#/R-RNO-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Rattus norvegicus 28276 R-SSC-77323 https://reactome.org/PathwayBrowser/#/R-SSC-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Sus scrofa 28276 R-SSC-77325 https://reactome.org/PathwayBrowser/#/R-SSC-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Sus scrofa 28276 R-XTR-77323 https://reactome.org/PathwayBrowser/#/R-XTR-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Xenopus tropicalis 28276 R-XTR-77325 https://reactome.org/PathwayBrowser/#/R-XTR-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Xenopus tropicalis 28279 R-BTA-158609 https://reactome.org/PathwayBrowser/#/R-BTA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Bos taurus 28279 R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 28279 R-BTA-9748983 https://reactome.org/PathwayBrowser/#/R-BTA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Bos taurus 28279 R-CFA-158609 https://reactome.org/PathwayBrowser/#/R-CFA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Canis familiaris 28279 R-CFA-9748983 https://reactome.org/PathwayBrowser/#/R-CFA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Canis familiaris 28279 R-DRE-158609 https://reactome.org/PathwayBrowser/#/R-DRE-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Danio rerio 28279 R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 28279 R-DRE-9748983 https://reactome.org/PathwayBrowser/#/R-DRE-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Danio rerio 28279 R-GGA-158609 https://reactome.org/PathwayBrowser/#/R-GGA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Gallus gallus 28279 R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 28279 R-GGA-9748983 https://reactome.org/PathwayBrowser/#/R-GGA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Gallus gallus 28279 R-HSA-158609 https://reactome.org/PathwayBrowser/#/R-HSA-158609 TPMT transfers CH3 from AdoMet to 6MP TAS Homo sapiens 28279 R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 28279 R-HSA-9748983 https://reactome.org/PathwayBrowser/#/R-HSA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP TAS Homo sapiens 28279 R-MMU-158609 https://reactome.org/PathwayBrowser/#/R-MMU-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Mus musculus 28279 R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 28279 R-MMU-9748983 https://reactome.org/PathwayBrowser/#/R-MMU-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Mus musculus 28279 R-RNO-158609 https://reactome.org/PathwayBrowser/#/R-RNO-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Rattus norvegicus 28279 R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 28279 R-RNO-9748983 https://reactome.org/PathwayBrowser/#/R-RNO-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Rattus norvegicus 28279 R-SSC-158609 https://reactome.org/PathwayBrowser/#/R-SSC-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Sus scrofa 28279 R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 28279 R-SSC-9748983 https://reactome.org/PathwayBrowser/#/R-SSC-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Sus scrofa 28279 R-XTR-158609 https://reactome.org/PathwayBrowser/#/R-XTR-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Xenopus tropicalis 28279 R-XTR-9748983 https://reactome.org/PathwayBrowser/#/R-XTR-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Xenopus tropicalis 28324 R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 28324 R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 28324 R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 28324 R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 28324 R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 28324 R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 28324 R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 28324 R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 28324 R-HSA-194025 https://reactome.org/PathwayBrowser/#/R-HSA-194025 11-deoxycortisol translocates to the mitochondrion TAS Homo sapiens 28324 R-HSA-5580292 https://reactome.org/PathwayBrowser/#/R-HSA-5580292 Defective CYP11B1 does not oxidise 11DCORT TAS Homo sapiens 28324 R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 28324 R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 28324 R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 28324 R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 28324 R-SSC-193981 https://reactome.org/PathwayBrowser/#/R-SSC-193981 CYP21A2 oxidises 17HPROG IEA Sus scrofa 28324 R-SSC-193997 https://reactome.org/PathwayBrowser/#/R-SSC-193997 CYP11B1 oxidises 11DCORT IEA Sus scrofa 28324 R-XTR-193997 https://reactome.org/PathwayBrowser/#/R-XTR-193997 CYP11B1 oxidises 11DCORT IEA Xenopus tropicalis 28325 R-BTA-77342 https://reactome.org/PathwayBrowser/#/R-BTA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Bos taurus 28325 R-BTA-77344 https://reactome.org/PathwayBrowser/#/R-BTA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Bos taurus 28325 R-CEL-77342 https://reactome.org/PathwayBrowser/#/R-CEL-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 28325 R-CEL-77344 https://reactome.org/PathwayBrowser/#/R-CEL-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Caenorhabditis elegans 28325 R-CFA-77342 https://reactome.org/PathwayBrowser/#/R-CFA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Canis familiaris 28325 R-CFA-77344 https://reactome.org/PathwayBrowser/#/R-CFA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Canis familiaris 28325 R-DDI-77344 https://reactome.org/PathwayBrowser/#/R-DDI-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Dictyostelium discoideum 28325 R-DME-77344 https://reactome.org/PathwayBrowser/#/R-DME-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Drosophila melanogaster 28325 R-DRE-77342 https://reactome.org/PathwayBrowser/#/R-DRE-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Danio rerio 28325 R-GGA-77342 https://reactome.org/PathwayBrowser/#/R-GGA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Gallus gallus 28325 R-HSA-77342 https://reactome.org/PathwayBrowser/#/R-HSA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H TAS Homo sapiens 28325 R-HSA-77344 https://reactome.org/PathwayBrowser/#/R-HSA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA TAS Homo sapiens 28325 R-MMU-77342 https://reactome.org/PathwayBrowser/#/R-MMU-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Mus musculus 28325 R-MMU-77344 https://reactome.org/PathwayBrowser/#/R-MMU-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Mus musculus 28325 R-RNO-77342 https://reactome.org/PathwayBrowser/#/R-RNO-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Rattus norvegicus 28325 R-RNO-77344 https://reactome.org/PathwayBrowser/#/R-RNO-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Rattus norvegicus 28325 R-SSC-77342 https://reactome.org/PathwayBrowser/#/R-SSC-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Sus scrofa 28325 R-SSC-77344 https://reactome.org/PathwayBrowser/#/R-SSC-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Sus scrofa 28325 R-XTR-77342 https://reactome.org/PathwayBrowser/#/R-XTR-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Xenopus tropicalis 28325 R-XTR-77344 https://reactome.org/PathwayBrowser/#/R-XTR-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Xenopus tropicalis 28329 R-HSA-9713837 https://reactome.org/PathwayBrowser/#/R-HSA-9713837 Psoralens in combination with UV generate DNA interstrand crosslinks TAS Homo sapiens 28364 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 28364 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 28364 R-BTA-400143 https://reactome.org/PathwayBrowser/#/R-BTA-400143 Fatty acid ligands activate PPARA IEA Bos taurus 28364 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 28364 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 28364 R-BTA-9018880 https://reactome.org/PathwayBrowser/#/R-BTA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Bos taurus 28364 R-BTA-9027628 https://reactome.org/PathwayBrowser/#/R-BTA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Bos taurus 28364 R-BTA-9028255 https://reactome.org/PathwayBrowser/#/R-BTA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Bos taurus 28364 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 28364 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 28364 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 28364 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 28364 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 28364 R-CFA-400143 https://reactome.org/PathwayBrowser/#/R-CFA-400143 Fatty acid ligands activate PPARA IEA Canis familiaris 28364 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 28364 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 28364 R-CFA-9018880 https://reactome.org/PathwayBrowser/#/R-CFA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Canis familiaris 28364 R-CFA-9027628 https://reactome.org/PathwayBrowser/#/R-CFA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Canis familiaris 28364 R-CFA-9028255 https://reactome.org/PathwayBrowser/#/R-CFA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Canis familiaris 28364 R-DDI-9027628 https://reactome.org/PathwayBrowser/#/R-DDI-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Dictyostelium discoideum 28364 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 28364 R-DME-400143 https://reactome.org/PathwayBrowser/#/R-DME-400143 Fatty acid ligands activate PPARA IEA Drosophila melanogaster 28364 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 28364 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 28364 R-DRE-400143 https://reactome.org/PathwayBrowser/#/R-DRE-400143 Fatty acid ligands activate PPARA IEA Danio rerio 28364 R-DRE-9018880 https://reactome.org/PathwayBrowser/#/R-DRE-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Danio rerio 28364 R-DRE-9027628 https://reactome.org/PathwayBrowser/#/R-DRE-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Danio rerio 28364 R-DRE-9028255 https://reactome.org/PathwayBrowser/#/R-DRE-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Danio rerio 28364 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 28364 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 28364 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus 28364 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 28364 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 28364 R-GGA-9018880 https://reactome.org/PathwayBrowser/#/R-GGA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Gallus gallus 28364 R-GGA-9027628 https://reactome.org/PathwayBrowser/#/R-GGA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Gallus gallus 28364 R-GGA-9028255 https://reactome.org/PathwayBrowser/#/R-GGA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Gallus gallus 28364 R-HSA-1368065 https://reactome.org/PathwayBrowser/#/R-HSA-1368065 Expression of NPAS2 IEA Homo sapiens 28364 R-HSA-1592238 https://reactome.org/PathwayBrowser/#/R-HSA-1592238 Expression of ALAS1 TAS Homo sapiens 28364 R-HSA-1655826 https://reactome.org/PathwayBrowser/#/R-HSA-1655826 Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) TAS Homo sapiens 28364 R-HSA-1655848 https://reactome.org/PathwayBrowser/#/R-HSA-1655848 Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) TAS Homo sapiens 28364 R-HSA-1655850 https://reactome.org/PathwayBrowser/#/R-HSA-1655850 Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) TAS Homo sapiens 28364 R-HSA-1801587 https://reactome.org/PathwayBrowser/#/R-HSA-1801587 Expression of CPT1A IEA Homo sapiens 28364 R-HSA-1989745 https://reactome.org/PathwayBrowser/#/R-HSA-1989745 Expression of ACADM TAS Homo sapiens 28364 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 28364 R-HSA-1989747 https://reactome.org/PathwayBrowser/#/R-HSA-1989747 Expression of FHL2 TAS Homo sapiens 28364 R-HSA-1989748 https://reactome.org/PathwayBrowser/#/R-HSA-1989748 Expression of GRHL1 TAS Homo sapiens 28364 R-HSA-1989749 https://reactome.org/PathwayBrowser/#/R-HSA-1989749 Expression of ACOX1 TAS Homo sapiens 28364 R-HSA-1989750 https://reactome.org/PathwayBrowser/#/R-HSA-1989750 Expression of FATP1 (SLC27A1) TAS Homo sapiens 28364 R-HSA-1989751 https://reactome.org/PathwayBrowser/#/R-HSA-1989751 Expression of FABP1 TAS Homo sapiens 28364 R-HSA-1989752 https://reactome.org/PathwayBrowser/#/R-HSA-1989752 Expression of TXNRD1 TAS Homo sapiens 28364 R-HSA-1989753 https://reactome.org/PathwayBrowser/#/R-HSA-1989753 Expression of PEX11A TAS Homo sapiens 28364 R-HSA-1989754 https://reactome.org/PathwayBrowser/#/R-HSA-1989754 Expression of APOA1 TAS Homo sapiens 28364 R-HSA-1989755 https://reactome.org/PathwayBrowser/#/R-HSA-1989755 Expression of CYP4A11 TAS Homo sapiens 28364 R-HSA-1989756 https://reactome.org/PathwayBrowser/#/R-HSA-1989756 Expression of ME1 TAS Homo sapiens 28364 R-HSA-1989757 https://reactome.org/PathwayBrowser/#/R-HSA-1989757 Expression of FADS1 TAS Homo sapiens 28364 R-HSA-1989758 https://reactome.org/PathwayBrowser/#/R-HSA-1989758 Expression of UGT1A9 TAS Homo sapiens 28364 R-HSA-1989759 https://reactome.org/PathwayBrowser/#/R-HSA-1989759 Expression of G0S2 TAS Homo sapiens 28364 R-HSA-1989760 https://reactome.org/PathwayBrowser/#/R-HSA-1989760 Expression of HMGCS2 TAS Homo sapiens 28364 R-HSA-1989761 https://reactome.org/PathwayBrowser/#/R-HSA-1989761 Expression of APOA5 TAS Homo sapiens 28364 R-HSA-1989762 https://reactome.org/PathwayBrowser/#/R-HSA-1989762 Expression of ABCB4 TAS Homo sapiens 28364 R-HSA-1989764 https://reactome.org/PathwayBrowser/#/R-HSA-1989764 Expression of CYP1A1 TAS Homo sapiens 28364 R-HSA-1989765 https://reactome.org/PathwayBrowser/#/R-HSA-1989765 Expression of ABCA1 TAS Homo sapiens 28364 R-HSA-1989767 https://reactome.org/PathwayBrowser/#/R-HSA-1989767 Expression of TRIB3 TAS Homo sapiens 28364 R-HSA-1989768 https://reactome.org/PathwayBrowser/#/R-HSA-1989768 Expression of TIAM2 TAS Homo sapiens 28364 R-HSA-1989770 https://reactome.org/PathwayBrowser/#/R-HSA-1989770 Expression of PLIN2 TAS Homo sapiens 28364 R-HSA-1989771 https://reactome.org/PathwayBrowser/#/R-HSA-1989771 Expression of TNFRSF21 TAS Homo sapiens 28364 R-HSA-1989772 https://reactome.org/PathwayBrowser/#/R-HSA-1989772 Expression of GLIPR1 TAS Homo sapiens 28364 R-HSA-1989773 https://reactome.org/PathwayBrowser/#/R-HSA-1989773 Expression of CPT2 TAS Homo sapiens 28364 R-HSA-1989774 https://reactome.org/PathwayBrowser/#/R-HSA-1989774 Expression of AGT TAS Homo sapiens 28364 R-HSA-1989775 https://reactome.org/PathwayBrowser/#/R-HSA-1989775 Expression of SULT2A1 TAS Homo sapiens 28364 R-HSA-1989776 https://reactome.org/PathwayBrowser/#/R-HSA-1989776 Expression of APOA2 TAS Homo sapiens 28364 R-HSA-1989777 https://reactome.org/PathwayBrowser/#/R-HSA-1989777 Expression of RGL1 TAS Homo sapiens 28364 R-HSA-1989778 https://reactome.org/PathwayBrowser/#/R-HSA-1989778 Expression of ACSL1 TAS Homo sapiens 28364 R-HSA-1989779 https://reactome.org/PathwayBrowser/#/R-HSA-1989779 Expression of ANKRD1 TAS Homo sapiens 28364 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 28364 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 28364 R-HSA-400143 https://reactome.org/PathwayBrowser/#/R-HSA-400143 Fatty acid ligands activate PPARA TAS Homo sapiens 28364 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 28364 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 28364 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 28364 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 28364 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 28364 R-HSA-879724 https://reactome.org/PathwayBrowser/#/R-HSA-879724 Expression of PPARA IEA Homo sapiens 28364 R-HSA-9018874 https://reactome.org/PathwayBrowser/#/R-HSA-9018874 CYP monooxygenates EPA to 18(S)-HpEPE TAS Homo sapiens 28364 R-HSA-9018880 https://reactome.org/PathwayBrowser/#/R-HSA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE TAS Homo sapiens 28364 R-HSA-9027628 https://reactome.org/PathwayBrowser/#/R-HSA-9027628 ALOX5 oxidises EPA to 5-HEPE TAS Homo sapiens 28364 R-HSA-9028255 https://reactome.org/PathwayBrowser/#/R-HSA-9028255 PTGS2 dimer oxidises EPA to PGH3 TAS Homo sapiens 28364 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 28364 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 28364 R-MMU-400143 https://reactome.org/PathwayBrowser/#/R-MMU-400143 Fatty acid ligands activate PPARA IEA Mus musculus 28364 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 28364 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 28364 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 28364 R-MMU-9018880 https://reactome.org/PathwayBrowser/#/R-MMU-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Mus musculus 28364 R-MMU-9027628 https://reactome.org/PathwayBrowser/#/R-MMU-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Mus musculus 28364 R-MMU-9028255 https://reactome.org/PathwayBrowser/#/R-MMU-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Mus musculus 28364 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 28364 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 28364 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus 28364 R-RNO-9018880 https://reactome.org/PathwayBrowser/#/R-RNO-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Rattus norvegicus 28364 R-RNO-9027628 https://reactome.org/PathwayBrowser/#/R-RNO-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Rattus norvegicus 28364 R-RNO-9028255 https://reactome.org/PathwayBrowser/#/R-RNO-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Rattus norvegicus 28364 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 28364 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 28364 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 28364 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 28364 R-SSC-9018880 https://reactome.org/PathwayBrowser/#/R-SSC-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Sus scrofa 28364 R-SSC-9027628 https://reactome.org/PathwayBrowser/#/R-SSC-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Sus scrofa 28364 R-SSC-9028255 https://reactome.org/PathwayBrowser/#/R-SSC-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Sus scrofa 28364 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 28364 R-XTR-9018880 https://reactome.org/PathwayBrowser/#/R-XTR-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Xenopus tropicalis 28364 R-XTR-9027628 https://reactome.org/PathwayBrowser/#/R-XTR-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Xenopus tropicalis 28364 R-XTR-9028255 https://reactome.org/PathwayBrowser/#/R-XTR-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Xenopus tropicalis 28387 R-BTA-109338 https://reactome.org/PathwayBrowser/#/R-BTA-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Bos taurus 28387 R-CFA-109338 https://reactome.org/PathwayBrowser/#/R-CFA-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Canis familiaris 28387 R-DME-109338 https://reactome.org/PathwayBrowser/#/R-DME-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Drosophila melanogaster 28387 R-GGA-109338 https://reactome.org/PathwayBrowser/#/R-GGA-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Gallus gallus 28387 R-HSA-109338 https://reactome.org/PathwayBrowser/#/R-HSA-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA TAS Homo sapiens 28387 R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 28387 R-MMU-109338 https://reactome.org/PathwayBrowser/#/R-MMU-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Mus musculus 28387 R-RNO-109338 https://reactome.org/PathwayBrowser/#/R-RNO-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Rattus norvegicus 28387 R-SSC-109338 https://reactome.org/PathwayBrowser/#/R-SSC-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Sus scrofa 28387 R-XTR-109338 https://reactome.org/PathwayBrowser/#/R-XTR-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Xenopus tropicalis 28424 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 28424 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 28424 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 28424 R-HSA-5228406 https://reactome.org/PathwayBrowser/#/R-HSA-5228406 tetX HC transports tetX LC from target cell endosome membrane into cytosol TAS Homo sapiens 28424 R-HSA-5228407 https://reactome.org/PathwayBrowser/#/R-HSA-5228407 tetX HC:LC binds target cell-surface gangliosides TAS Homo sapiens 28424 R-HSA-5228408 https://reactome.org/PathwayBrowser/#/R-HSA-5228408 Retrograde transport of internalized tetX HC:LC:gangliosides TAS Homo sapiens 28424 R-HSA-5228411 https://reactome.org/PathwayBrowser/#/R-HSA-5228411 Clathrin-mediated endocytosis of tetX HC:LC:gangliosides TAS Homo sapiens 28424 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 28424 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 28424 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 28424 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 28424 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 28424 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 28442 R-HSA-2161662 https://reactome.org/PathwayBrowser/#/R-HSA-2161662 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD IEA Homo sapiens 28442 R-HSA-2161692 https://reactome.org/PathwayBrowser/#/R-HSA-2161692 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1 IEA Homo sapiens 28442 R-MMU-2161638 https://reactome.org/PathwayBrowser/#/R-MMU-2161638 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by Ptgr2 TAS Mus musculus 28442 R-OCU-2161568 https://reactome.org/PathwayBrowser/#/R-OCU-2161568 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD TAS Oryctolagus cuniculus 28450 R-HSA-2408540 https://reactome.org/PathwayBrowser/#/R-HSA-2408540 APSe is phosphorylated to PAPSe by PAPSS1,2 IEA Homo sapiens 28450 R-HSA-2408548 https://reactome.org/PathwayBrowser/#/R-HSA-2408548 PAPSe is reduced to SeO3(2-) by PAPSe reductase IEA Homo sapiens 28450 R-PCH-2408503 https://reactome.org/PathwayBrowser/#/R-PCH-2408503 APSe is phosphorylated to PAPSe by Kaps TAS Penicillium chrysogenum 28450 R-SCE-2408518 https://reactome.org/PathwayBrowser/#/R-SCE-2408518 PAPSe is reduced to SeO3(2-) by MET16 TAS Saccharomyces cerevisiae 28477 R-BTA-192067 https://reactome.org/PathwayBrowser/#/R-BTA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Bos taurus 28477 R-CEL-192067 https://reactome.org/PathwayBrowser/#/R-CEL-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Caenorhabditis elegans 28477 R-CFA-192067 https://reactome.org/PathwayBrowser/#/R-CFA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Canis familiaris 28477 R-CFA-192157 https://reactome.org/PathwayBrowser/#/R-CFA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Canis familiaris 28477 R-DDI-192067 https://reactome.org/PathwayBrowser/#/R-DDI-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Dictyostelium discoideum 28477 R-DME-192067 https://reactome.org/PathwayBrowser/#/R-DME-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Drosophila melanogaster 28477 R-DRE-192157 https://reactome.org/PathwayBrowser/#/R-DRE-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Danio rerio 28477 R-GGA-192067 https://reactome.org/PathwayBrowser/#/R-GGA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Gallus gallus 28477 R-HSA-192067 https://reactome.org/PathwayBrowser/#/R-HSA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one TAS Homo sapiens 28477 R-HSA-192157 https://reactome.org/PathwayBrowser/#/R-HSA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE TAS Homo sapiens 28477 R-MMU-192067 https://reactome.org/PathwayBrowser/#/R-MMU-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Mus musculus 28477 R-MMU-192157 https://reactome.org/PathwayBrowser/#/R-MMU-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Mus musculus 28477 R-RNO-192067 https://reactome.org/PathwayBrowser/#/R-RNO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Rattus norvegicus 28477 R-RNO-192157 https://reactome.org/PathwayBrowser/#/R-RNO-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Rattus norvegicus 28477 R-SCE-192067 https://reactome.org/PathwayBrowser/#/R-SCE-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Saccharomyces cerevisiae 28477 R-SPO-192067 https://reactome.org/PathwayBrowser/#/R-SPO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Schizosaccharomyces pombe 28477 R-SSC-192067 https://reactome.org/PathwayBrowser/#/R-SSC-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Sus scrofa 28477 R-SSC-192157 https://reactome.org/PathwayBrowser/#/R-SSC-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Sus scrofa 28477 R-XTR-192067 https://reactome.org/PathwayBrowser/#/R-XTR-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Xenopus tropicalis 28477 R-XTR-192157 https://reactome.org/PathwayBrowser/#/R-XTR-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Xenopus tropicalis 28484 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 28484 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 28484 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 28484 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 28484 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 28484 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 28484 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 28484 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 28484 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 28493 R-BTA-77309 https://reactome.org/PathwayBrowser/#/R-BTA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Bos taurus 28493 R-BTA-77345 https://reactome.org/PathwayBrowser/#/R-BTA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Bos taurus 28493 R-BTA-8952873 https://reactome.org/PathwayBrowser/#/R-BTA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Bos taurus 28493 R-CEL-77309 https://reactome.org/PathwayBrowser/#/R-CEL-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Caenorhabditis elegans 28493 R-CEL-77345 https://reactome.org/PathwayBrowser/#/R-CEL-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 28493 R-CEL-8952873 https://reactome.org/PathwayBrowser/#/R-CEL-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Caenorhabditis elegans 28493 R-CFA-77309 https://reactome.org/PathwayBrowser/#/R-CFA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Canis familiaris 28493 R-CFA-77345 https://reactome.org/PathwayBrowser/#/R-CFA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Canis familiaris 28493 R-CFA-8952873 https://reactome.org/PathwayBrowser/#/R-CFA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Canis familiaris 28493 R-DDI-8952873 https://reactome.org/PathwayBrowser/#/R-DDI-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Dictyostelium discoideum 28493 R-DME-77309 https://reactome.org/PathwayBrowser/#/R-DME-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Drosophila melanogaster 28493 R-DME-77345 https://reactome.org/PathwayBrowser/#/R-DME-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 28493 R-DME-8952873 https://reactome.org/PathwayBrowser/#/R-DME-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Drosophila melanogaster 28493 R-DRE-77309 https://reactome.org/PathwayBrowser/#/R-DRE-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Danio rerio 28493 R-DRE-8952873 https://reactome.org/PathwayBrowser/#/R-DRE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Danio rerio 28493 R-GGA-77309 https://reactome.org/PathwayBrowser/#/R-GGA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Gallus gallus 28493 R-GGA-77345 https://reactome.org/PathwayBrowser/#/R-GGA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Gallus gallus 28493 R-GGA-8952873 https://reactome.org/PathwayBrowser/#/R-GGA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Gallus gallus 28493 R-HSA-77309 https://reactome.org/PathwayBrowser/#/R-HSA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA TAS Homo sapiens 28493 R-HSA-77345 https://reactome.org/PathwayBrowser/#/R-HSA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 TAS Homo sapiens 28493 R-HSA-8952873 https://reactome.org/PathwayBrowser/#/R-HSA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA TAS Homo sapiens 28493 R-MMU-77309 https://reactome.org/PathwayBrowser/#/R-MMU-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Mus musculus 28493 R-MMU-77345 https://reactome.org/PathwayBrowser/#/R-MMU-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Mus musculus 28493 R-MMU-8952873 https://reactome.org/PathwayBrowser/#/R-MMU-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Mus musculus 28493 R-RNO-77309 https://reactome.org/PathwayBrowser/#/R-RNO-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Rattus norvegicus 28493 R-RNO-77345 https://reactome.org/PathwayBrowser/#/R-RNO-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 28493 R-RNO-8952873 https://reactome.org/PathwayBrowser/#/R-RNO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Rattus norvegicus 28493 R-SCE-8952873 https://reactome.org/PathwayBrowser/#/R-SCE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Saccharomyces cerevisiae 28493 R-SPO-8952873 https://reactome.org/PathwayBrowser/#/R-SPO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Schizosaccharomyces pombe 28493 R-SSC-77309 https://reactome.org/PathwayBrowser/#/R-SSC-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Sus scrofa 28493 R-SSC-77345 https://reactome.org/PathwayBrowser/#/R-SSC-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Sus scrofa 28493 R-SSC-8952873 https://reactome.org/PathwayBrowser/#/R-SSC-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Sus scrofa 28493 R-XTR-77309 https://reactome.org/PathwayBrowser/#/R-XTR-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Xenopus tropicalis 28493 R-XTR-8952873 https://reactome.org/PathwayBrowser/#/R-XTR-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Xenopus tropicalis 28494 R-BTA-114284 https://reactome.org/PathwayBrowser/#/R-BTA-114284 Release of Cytochrome c from mitochondria IEA Bos taurus 28494 R-BTA-1482775 https://reactome.org/PathwayBrowser/#/R-BTA-1482775 MLCL is acylated to CL by HADH (IM) IEA Bos taurus 28494 R-BTA-1482781 https://reactome.org/PathwayBrowser/#/R-BTA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Bos taurus 28494 R-BTA-1482794 https://reactome.org/PathwayBrowser/#/R-BTA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Bos taurus 28494 R-BTA-1482850 https://reactome.org/PathwayBrowser/#/R-BTA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Bos taurus 28494 R-BTA-1482861 https://reactome.org/PathwayBrowser/#/R-BTA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Bos taurus 28494 R-BTA-1482894 https://reactome.org/PathwayBrowser/#/R-BTA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Bos taurus 28494 R-BTA-1483063 https://reactome.org/PathwayBrowser/#/R-BTA-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Bos taurus 28494 R-BTA-8954398 https://reactome.org/PathwayBrowser/#/R-BTA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Bos taurus 28494 R-BTA-9647643 https://reactome.org/PathwayBrowser/#/R-BTA-9647643 GSDMD (1-275) binds bacterial cardiolipin IEA Bos taurus 28494 R-BTA-9710353 https://reactome.org/PathwayBrowser/#/R-BTA-9710353 GSDMD (1-275) binds cardiolipin IEA Bos taurus 28494 R-BTA-9710354 https://reactome.org/PathwayBrowser/#/R-BTA-9710354 GSDME (1-270) binds cardiolipin IEA Bos taurus 28494 R-CEL-1482775 https://reactome.org/PathwayBrowser/#/R-CEL-1482775 MLCL is acylated to CL by HADH (IM) IEA Caenorhabditis elegans 28494 R-CEL-1482781 https://reactome.org/PathwayBrowser/#/R-CEL-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 28494 R-CEL-1482794 https://reactome.org/PathwayBrowser/#/R-CEL-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 28494 R-CEL-1482850 https://reactome.org/PathwayBrowser/#/R-CEL-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 28494 R-CEL-1482861 https://reactome.org/PathwayBrowser/#/R-CEL-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Caenorhabditis elegans 28494 R-CEL-1482894 https://reactome.org/PathwayBrowser/#/R-CEL-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 28494 R-CEL-1483063 https://reactome.org/PathwayBrowser/#/R-CEL-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Caenorhabditis elegans 28494 R-CFA-114284 https://reactome.org/PathwayBrowser/#/R-CFA-114284 Release of Cytochrome c from mitochondria IEA Canis familiaris 28494 R-CFA-1482775 https://reactome.org/PathwayBrowser/#/R-CFA-1482775 MLCL is acylated to CL by HADH (IM) IEA Canis familiaris 28494 R-CFA-1482781 https://reactome.org/PathwayBrowser/#/R-CFA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Canis familiaris 28494 R-CFA-1482794 https://reactome.org/PathwayBrowser/#/R-CFA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Canis familiaris 28494 R-CFA-1482850 https://reactome.org/PathwayBrowser/#/R-CFA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Canis familiaris 28494 R-CFA-1482861 https://reactome.org/PathwayBrowser/#/R-CFA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Canis familiaris 28494 R-CFA-1482894 https://reactome.org/PathwayBrowser/#/R-CFA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Canis familiaris 28494 R-CFA-8954398 https://reactome.org/PathwayBrowser/#/R-CFA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Canis familiaris 28494 R-CFA-9647643 https://reactome.org/PathwayBrowser/#/R-CFA-9647643 GSDMD (1-275) binds bacterial cardiolipin IEA Canis familiaris 28494 R-CFA-9710353 https://reactome.org/PathwayBrowser/#/R-CFA-9710353 GSDMD (1-275) binds cardiolipin IEA Canis familiaris 28494 R-CFA-9710354 https://reactome.org/PathwayBrowser/#/R-CFA-9710354 GSDME (1-270) binds cardiolipin IEA Canis familiaris 28494 R-DDI-1482781 https://reactome.org/PathwayBrowser/#/R-DDI-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 28494 R-DDI-1482794 https://reactome.org/PathwayBrowser/#/R-DDI-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 28494 R-DDI-1482850 https://reactome.org/PathwayBrowser/#/R-DDI-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 28494 R-DDI-1482861 https://reactome.org/PathwayBrowser/#/R-DDI-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Dictyostelium discoideum 28494 R-DDI-1482894 https://reactome.org/PathwayBrowser/#/R-DDI-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 28494 R-DDI-8954398 https://reactome.org/PathwayBrowser/#/R-DDI-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Dictyostelium discoideum 28494 R-DME-1482775 https://reactome.org/PathwayBrowser/#/R-DME-1482775 MLCL is acylated to CL by HADH (IM) IEA Drosophila melanogaster 28494 R-DME-1482781 https://reactome.org/PathwayBrowser/#/R-DME-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Drosophila melanogaster 28494 R-DME-1482794 https://reactome.org/PathwayBrowser/#/R-DME-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Drosophila melanogaster 28494 R-DME-1482850 https://reactome.org/PathwayBrowser/#/R-DME-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Drosophila melanogaster 28494 R-DME-1482894 https://reactome.org/PathwayBrowser/#/R-DME-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Drosophila melanogaster 28494 R-DME-1483063 https://reactome.org/PathwayBrowser/#/R-DME-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Drosophila melanogaster 28494 R-DME-8954398 https://reactome.org/PathwayBrowser/#/R-DME-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Drosophila melanogaster 28494 R-DRE-114284 https://reactome.org/PathwayBrowser/#/R-DRE-114284 Release of Cytochrome c from mitochondria IEA Danio rerio 28494 R-DRE-1482775 https://reactome.org/PathwayBrowser/#/R-DRE-1482775 MLCL is acylated to CL by HADH (IM) IEA Danio rerio 28494 R-DRE-1482781 https://reactome.org/PathwayBrowser/#/R-DRE-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Danio rerio 28494 R-DRE-1482794 https://reactome.org/PathwayBrowser/#/R-DRE-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Danio rerio 28494 R-DRE-1482850 https://reactome.org/PathwayBrowser/#/R-DRE-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Danio rerio 28494 R-DRE-1482861 https://reactome.org/PathwayBrowser/#/R-DRE-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Danio rerio 28494 R-DRE-1482894 https://reactome.org/PathwayBrowser/#/R-DRE-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Danio rerio 28494 R-DRE-1483063 https://reactome.org/PathwayBrowser/#/R-DRE-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Danio rerio 28494 R-DRE-8954398 https://reactome.org/PathwayBrowser/#/R-DRE-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Danio rerio 28494 R-DRE-9710354 https://reactome.org/PathwayBrowser/#/R-DRE-9710354 GSDME (1-270) binds cardiolipin IEA Danio rerio 28494 R-GGA-114284 https://reactome.org/PathwayBrowser/#/R-GGA-114284 Release of Cytochrome c from mitochondria IEA Gallus gallus 28494 R-GGA-1482775 https://reactome.org/PathwayBrowser/#/R-GGA-1482775 MLCL is acylated to CL by HADH (IM) IEA Gallus gallus 28494 R-GGA-1482781 https://reactome.org/PathwayBrowser/#/R-GGA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Gallus gallus 28494 R-GGA-1482794 https://reactome.org/PathwayBrowser/#/R-GGA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Gallus gallus 28494 R-GGA-1482850 https://reactome.org/PathwayBrowser/#/R-GGA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Gallus gallus 28494 R-GGA-1482861 https://reactome.org/PathwayBrowser/#/R-GGA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Gallus gallus 28494 R-GGA-1482894 https://reactome.org/PathwayBrowser/#/R-GGA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Gallus gallus 28494 R-GGA-1483063 https://reactome.org/PathwayBrowser/#/R-GGA-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Gallus gallus 28494 R-GGA-8954398 https://reactome.org/PathwayBrowser/#/R-GGA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Gallus gallus 28494 R-GGA-9647643 https://reactome.org/PathwayBrowser/#/R-GGA-9647643 GSDMD (1-275) binds bacterial cardiolipin IEA Gallus gallus 28494 R-GGA-9710353 https://reactome.org/PathwayBrowser/#/R-GGA-9710353 GSDMD (1-275) binds cardiolipin IEA Gallus gallus 28494 R-GGA-9710354 https://reactome.org/PathwayBrowser/#/R-GGA-9710354 GSDME (1-270) binds cardiolipin IEA Gallus gallus 28494 R-HSA-114284 https://reactome.org/PathwayBrowser/#/R-HSA-114284 Release of Cytochrome c from mitochondria TAS Homo sapiens 28494 R-HSA-1482775 https://reactome.org/PathwayBrowser/#/R-HSA-1482775 MLCL is acylated to CL by HADH (IM) TAS Homo sapiens 28494 R-HSA-1482778 https://reactome.org/PathwayBrowser/#/R-HSA-1482778 CL is hydrolyzed to MLCL by PLA2G6 (IM) IEA Homo sapiens 28494 R-HSA-1482781 https://reactome.org/PathwayBrowser/#/R-HSA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) TAS Homo sapiens 28494 R-HSA-1482794 https://reactome.org/PathwayBrowser/#/R-HSA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) TAS Homo sapiens 28494 R-HSA-1482850 https://reactome.org/PathwayBrowser/#/R-HSA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) TAS Homo sapiens 28494 R-HSA-1482857 https://reactome.org/PathwayBrowser/#/R-HSA-1482857 CL transports from the ER to the IM TAS Homo sapiens 28494 R-HSA-1482861 https://reactome.org/PathwayBrowser/#/R-HSA-1482861 MLCL is acylated to CL by LCLAT1 (ER) TAS Homo sapiens 28494 R-HSA-1482894 https://reactome.org/PathwayBrowser/#/R-HSA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) TAS Homo sapiens 28494 R-HSA-1483063 https://reactome.org/PathwayBrowser/#/R-HSA-1483063 PG and CDP-DAG are converted to CL by CRLS1 TAS Homo sapiens 28494 R-HSA-8954398 https://reactome.org/PathwayBrowser/#/R-HSA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG TAS Homo sapiens 28494 R-HSA-9647643 https://reactome.org/PathwayBrowser/#/R-HSA-9647643 GSDMD (1-275) binds bacterial cardiolipin TAS Homo sapiens 28494 R-HSA-9710353 https://reactome.org/PathwayBrowser/#/R-HSA-9710353 GSDMD (1-275) binds cardiolipin TAS Homo sapiens 28494 R-HSA-9710354 https://reactome.org/PathwayBrowser/#/R-HSA-9710354 GSDME (1-270) binds cardiolipin TAS Homo sapiens 28494 R-MMU-114284 https://reactome.org/PathwayBrowser/#/R-MMU-114284 Release of Cytochrome c from mitochondria IEA Mus musculus 28494 R-MMU-1482775 https://reactome.org/PathwayBrowser/#/R-MMU-1482775 MLCL is acylated to CL by HADH (IM) IEA Mus musculus 28494 R-MMU-1482781 https://reactome.org/PathwayBrowser/#/R-MMU-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Mus musculus 28494 R-MMU-1482794 https://reactome.org/PathwayBrowser/#/R-MMU-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Mus musculus 28494 R-MMU-1482850 https://reactome.org/PathwayBrowser/#/R-MMU-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Mus musculus 28494 R-MMU-1482861 https://reactome.org/PathwayBrowser/#/R-MMU-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Mus musculus 28494 R-MMU-1482894 https://reactome.org/PathwayBrowser/#/R-MMU-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Mus musculus 28494 R-MMU-1483063 https://reactome.org/PathwayBrowser/#/R-MMU-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Mus musculus 28494 R-MMU-8954398 https://reactome.org/PathwayBrowser/#/R-MMU-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Mus musculus 28494 R-MMU-9647643 https://reactome.org/PathwayBrowser/#/R-MMU-9647643 GSDMD (1-275) binds bacterial cardiolipin IEA Mus musculus 28494 R-MMU-9710353 https://reactome.org/PathwayBrowser/#/R-MMU-9710353 GSDMD (1-275) binds cardiolipin IEA Mus musculus 28494 R-MMU-9710354 https://reactome.org/PathwayBrowser/#/R-MMU-9710354 GSDME (1-270) binds cardiolipin IEA Mus musculus 28494 R-RNO-114284 https://reactome.org/PathwayBrowser/#/R-RNO-114284 Release of Cytochrome c from mitochondria IEA Rattus norvegicus 28494 R-RNO-1482775 https://reactome.org/PathwayBrowser/#/R-RNO-1482775 MLCL is acylated to CL by HADH (IM) IEA Rattus norvegicus 28494 R-RNO-1482781 https://reactome.org/PathwayBrowser/#/R-RNO-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Rattus norvegicus 28494 R-RNO-1482794 https://reactome.org/PathwayBrowser/#/R-RNO-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Rattus norvegicus 28494 R-RNO-1482836 https://reactome.org/PathwayBrowser/#/R-RNO-1482836 CL is hydrolyzed to MLCL by Pla2g6 (IM) TAS Rattus norvegicus 28494 R-RNO-1482850 https://reactome.org/PathwayBrowser/#/R-RNO-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Rattus norvegicus 28494 R-RNO-1482861 https://reactome.org/PathwayBrowser/#/R-RNO-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Rattus norvegicus 28494 R-RNO-1482894 https://reactome.org/PathwayBrowser/#/R-RNO-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Rattus norvegicus 28494 R-RNO-1483063 https://reactome.org/PathwayBrowser/#/R-RNO-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Rattus norvegicus 28494 R-RNO-8954398 https://reactome.org/PathwayBrowser/#/R-RNO-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Rattus norvegicus 28494 R-RNO-9647643 https://reactome.org/PathwayBrowser/#/R-RNO-9647643 GSDMD (1-275) binds bacterial cardiolipin IEA Rattus norvegicus 28494 R-RNO-9710353 https://reactome.org/PathwayBrowser/#/R-RNO-9710353 GSDMD (1-275) binds cardiolipin IEA Rattus norvegicus 28494 R-RNO-9710354 https://reactome.org/PathwayBrowser/#/R-RNO-9710354 GSDME (1-270) binds cardiolipin IEA Rattus norvegicus 28494 R-SCE-1482781 https://reactome.org/PathwayBrowser/#/R-SCE-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 28494 R-SCE-1482794 https://reactome.org/PathwayBrowser/#/R-SCE-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 28494 R-SCE-1482850 https://reactome.org/PathwayBrowser/#/R-SCE-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 28494 R-SCE-1482861 https://reactome.org/PathwayBrowser/#/R-SCE-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Saccharomyces cerevisiae 28494 R-SCE-1482894 https://reactome.org/PathwayBrowser/#/R-SCE-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 28494 R-SCE-1483063 https://reactome.org/PathwayBrowser/#/R-SCE-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Saccharomyces cerevisiae 28494 R-SPO-1482861 https://reactome.org/PathwayBrowser/#/R-SPO-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Schizosaccharomyces pombe 28494 R-SPO-1483063 https://reactome.org/PathwayBrowser/#/R-SPO-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Schizosaccharomyces pombe 28494 R-SSC-114284 https://reactome.org/PathwayBrowser/#/R-SSC-114284 Release of Cytochrome c from mitochondria IEA Sus scrofa 28494 R-SSC-1482775 https://reactome.org/PathwayBrowser/#/R-SSC-1482775 MLCL is acylated to CL by HADH (IM) IEA Sus scrofa 28494 R-SSC-1482781 https://reactome.org/PathwayBrowser/#/R-SSC-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Sus scrofa 28494 R-SSC-1482794 https://reactome.org/PathwayBrowser/#/R-SSC-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Sus scrofa 28494 R-SSC-1482850 https://reactome.org/PathwayBrowser/#/R-SSC-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Sus scrofa 28494 R-SSC-1482861 https://reactome.org/PathwayBrowser/#/R-SSC-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Sus scrofa 28494 R-SSC-1482894 https://reactome.org/PathwayBrowser/#/R-SSC-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Sus scrofa 28494 R-SSC-1483063 https://reactome.org/PathwayBrowser/#/R-SSC-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Sus scrofa 28494 R-SSC-8954398 https://reactome.org/PathwayBrowser/#/R-SSC-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Sus scrofa 28494 R-SSC-9647643 https://reactome.org/PathwayBrowser/#/R-SSC-9647643 GSDMD (1-275) binds bacterial cardiolipin IEA Sus scrofa 28494 R-SSC-9710353 https://reactome.org/PathwayBrowser/#/R-SSC-9710353 GSDMD (1-275) binds cardiolipin IEA Sus scrofa 28494 R-SSC-9710354 https://reactome.org/PathwayBrowser/#/R-SSC-9710354 GSDME (1-270) binds cardiolipin IEA Sus scrofa 28494 R-XTR-114284 https://reactome.org/PathwayBrowser/#/R-XTR-114284 Release of Cytochrome c from mitochondria IEA Xenopus tropicalis 28494 R-XTR-1482775 https://reactome.org/PathwayBrowser/#/R-XTR-1482775 MLCL is acylated to CL by HADH (IM) IEA Xenopus tropicalis 28494 R-XTR-1482781 https://reactome.org/PathwayBrowser/#/R-XTR-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Xenopus tropicalis 28494 R-XTR-1482794 https://reactome.org/PathwayBrowser/#/R-XTR-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Xenopus tropicalis 28494 R-XTR-1482850 https://reactome.org/PathwayBrowser/#/R-XTR-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Xenopus tropicalis 28494 R-XTR-1482861 https://reactome.org/PathwayBrowser/#/R-XTR-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Xenopus tropicalis 28494 R-XTR-1482894 https://reactome.org/PathwayBrowser/#/R-XTR-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Xenopus tropicalis 28494 R-XTR-8954398 https://reactome.org/PathwayBrowser/#/R-XTR-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Xenopus tropicalis 28494 R-XTR-9710354 https://reactome.org/PathwayBrowser/#/R-XTR-9710354 GSDME (1-270) binds cardiolipin IEA Xenopus tropicalis 28497 R-HSA-5333609 https://reactome.org/PathwayBrowser/#/R-HSA-5333609 MeSebGalNac is hydrolysed to MeSeH and bGalNac IEA Homo sapiens 28497 R-RNO-5333611 https://reactome.org/PathwayBrowser/#/R-RNO-5333611 MeSebGalNac is hydrolysed to MeSeH and bGalNac TAS Rattus norvegicus 28497 R-RNO-5333617 https://reactome.org/PathwayBrowser/#/R-RNO-5333617 GSSeH combines with bGalNAc derivative to form GSSebGalNac TAS Rattus norvegicus 28509 R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 28509 R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 28509 R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 28509 R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 28509 R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 28509 R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 28509 R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 28509 R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 28509 R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 28509 R-RNO-76354 https://reactome.org/PathwayBrowser/#/R-RNO-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Rattus norvegicus 28509 R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa 28509 R-XTR-76354 https://reactome.org/PathwayBrowser/#/R-XTR-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Xenopus tropicalis 28528 R-BTA-77340 https://reactome.org/PathwayBrowser/#/R-BTA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Bos taurus 28528 R-BTA-77342 https://reactome.org/PathwayBrowser/#/R-BTA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Bos taurus 28528 R-CEL-77340 https://reactome.org/PathwayBrowser/#/R-CEL-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Caenorhabditis elegans 28528 R-CEL-77342 https://reactome.org/PathwayBrowser/#/R-CEL-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 28528 R-CFA-77340 https://reactome.org/PathwayBrowser/#/R-CFA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Canis familiaris 28528 R-CFA-77342 https://reactome.org/PathwayBrowser/#/R-CFA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Canis familiaris 28528 R-DME-77340 https://reactome.org/PathwayBrowser/#/R-DME-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Drosophila melanogaster 28528 R-DRE-77340 https://reactome.org/PathwayBrowser/#/R-DRE-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Danio rerio 28528 R-DRE-77342 https://reactome.org/PathwayBrowser/#/R-DRE-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Danio rerio 28528 R-GGA-77340 https://reactome.org/PathwayBrowser/#/R-GGA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Gallus gallus 28528 R-GGA-77342 https://reactome.org/PathwayBrowser/#/R-GGA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Gallus gallus 28528 R-HSA-77340 https://reactome.org/PathwayBrowser/#/R-HSA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA TAS Homo sapiens 28528 R-HSA-77342 https://reactome.org/PathwayBrowser/#/R-HSA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H TAS Homo sapiens 28528 R-MMU-77340 https://reactome.org/PathwayBrowser/#/R-MMU-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Mus musculus 28528 R-MMU-77342 https://reactome.org/PathwayBrowser/#/R-MMU-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Mus musculus 28528 R-RNO-77340 https://reactome.org/PathwayBrowser/#/R-RNO-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Rattus norvegicus 28528 R-RNO-77342 https://reactome.org/PathwayBrowser/#/R-RNO-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Rattus norvegicus 28528 R-SSC-77340 https://reactome.org/PathwayBrowser/#/R-SSC-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Sus scrofa 28528 R-SSC-77342 https://reactome.org/PathwayBrowser/#/R-SSC-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Sus scrofa 28528 R-XTR-77340 https://reactome.org/PathwayBrowser/#/R-XTR-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Xenopus tropicalis 28528 R-XTR-77342 https://reactome.org/PathwayBrowser/#/R-XTR-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Xenopus tropicalis 2853 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 2853 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2853 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2853 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2853 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 2853 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 2853 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2853 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2853 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2853 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 2853 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 2853 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2853 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 2853 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 2853 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2853 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 2853 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2853 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 2853 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 2853 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2853 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2853 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2853 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 2853 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 2853 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 2853 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 2853 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2853 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2853 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2853 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 2853 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 2853 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2853 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 2853 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 2853 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2853 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2853 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2853 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 2853 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 2853 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2853 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 2853 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 28533 R-BTA-193508 https://reactome.org/PathwayBrowser/#/R-BTA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 28533 R-BTA-193533 https://reactome.org/PathwayBrowser/#/R-BTA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Bos taurus 28533 R-CEL-193508 https://reactome.org/PathwayBrowser/#/R-CEL-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 28533 R-CFA-193508 https://reactome.org/PathwayBrowser/#/R-CFA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 28533 R-CFA-193533 https://reactome.org/PathwayBrowser/#/R-CFA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Canis familiaris 28533 R-DDI-193508 https://reactome.org/PathwayBrowser/#/R-DDI-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 28533 R-DME-193508 https://reactome.org/PathwayBrowser/#/R-DME-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 28533 R-DME-193533 https://reactome.org/PathwayBrowser/#/R-DME-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Drosophila melanogaster 28533 R-DRE-193533 https://reactome.org/PathwayBrowser/#/R-DRE-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Danio rerio 28533 R-GGA-193508 https://reactome.org/PathwayBrowser/#/R-GGA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 28533 R-GGA-193533 https://reactome.org/PathwayBrowser/#/R-GGA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Gallus gallus 28533 R-HSA-193508 https://reactome.org/PathwayBrowser/#/R-HSA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 28533 R-HSA-193533 https://reactome.org/PathwayBrowser/#/R-HSA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA TAS Homo sapiens 28533 R-MMU-193508 https://reactome.org/PathwayBrowser/#/R-MMU-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 28533 R-MMU-193533 https://reactome.org/PathwayBrowser/#/R-MMU-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Mus musculus 28533 R-RNO-193508 https://reactome.org/PathwayBrowser/#/R-RNO-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 28533 R-RNO-193533 https://reactome.org/PathwayBrowser/#/R-RNO-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Rattus norvegicus 28540 R-BTA-193393 https://reactome.org/PathwayBrowser/#/R-BTA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Bos taurus 28540 R-BTA-193497 https://reactome.org/PathwayBrowser/#/R-BTA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Bos taurus 28540 R-BTA-193841 https://reactome.org/PathwayBrowser/#/R-BTA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Bos taurus 28540 R-CEL-193841 https://reactome.org/PathwayBrowser/#/R-CEL-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Caenorhabditis elegans 28540 R-CFA-193393 https://reactome.org/PathwayBrowser/#/R-CFA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Canis familiaris 28540 R-CFA-193497 https://reactome.org/PathwayBrowser/#/R-CFA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Canis familiaris 28540 R-DDI-193841 https://reactome.org/PathwayBrowser/#/R-DDI-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Dictyostelium discoideum 28540 R-DME-193841 https://reactome.org/PathwayBrowser/#/R-DME-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Drosophila melanogaster 28540 R-HSA-193393 https://reactome.org/PathwayBrowser/#/R-HSA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol TAS Homo sapiens 28540 R-HSA-193497 https://reactome.org/PathwayBrowser/#/R-HSA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al TAS Homo sapiens 28540 R-HSA-193808 https://reactome.org/PathwayBrowser/#/R-HSA-193808 5beta-cholestan-3alpha,7alpha,27-triol is translocated from the cytosol to the mitochondrial matrix TAS Homo sapiens 28540 R-HSA-193841 https://reactome.org/PathwayBrowser/#/R-HSA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol TAS Homo sapiens 28540 R-MMU-193393 https://reactome.org/PathwayBrowser/#/R-MMU-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Mus musculus 28540 R-MMU-193497 https://reactome.org/PathwayBrowser/#/R-MMU-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Mus musculus 28540 R-MMU-193841 https://reactome.org/PathwayBrowser/#/R-MMU-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Mus musculus 28540 R-RNO-193393 https://reactome.org/PathwayBrowser/#/R-RNO-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Rattus norvegicus 28540 R-RNO-193497 https://reactome.org/PathwayBrowser/#/R-RNO-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Rattus norvegicus 28540 R-RNO-193841 https://reactome.org/PathwayBrowser/#/R-RNO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Rattus norvegicus 28540 R-SCE-193841 https://reactome.org/PathwayBrowser/#/R-SCE-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Saccharomyces cerevisiae 28540 R-SPO-193841 https://reactome.org/PathwayBrowser/#/R-SPO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Schizosaccharomyces pombe 28540 R-SSC-193393 https://reactome.org/PathwayBrowser/#/R-SSC-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Sus scrofa 28540 R-SSC-193497 https://reactome.org/PathwayBrowser/#/R-SSC-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Sus scrofa 28540 R-SSC-193841 https://reactome.org/PathwayBrowser/#/R-SSC-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Sus scrofa 28540 R-XTR-193841 https://reactome.org/PathwayBrowser/#/R-XTR-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Xenopus tropicalis 28579 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 28579 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 28579 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 28579 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 28579 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 28579 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 28579 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 28579 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 28579 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 28579 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 28591 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 28591 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 28591 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 28591 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 28591 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 28591 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 28591 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 28591 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 28591 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 28593 R-BTA-597628 https://reactome.org/PathwayBrowser/#/R-BTA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Bos taurus 28593 R-CEL-597628 https://reactome.org/PathwayBrowser/#/R-CEL-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Caenorhabditis elegans 28593 R-CFA-597628 https://reactome.org/PathwayBrowser/#/R-CFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Canis familiaris 28593 R-DRE-597628 https://reactome.org/PathwayBrowser/#/R-DRE-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Danio rerio 28593 R-GGA-597628 https://reactome.org/PathwayBrowser/#/R-GGA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Gallus gallus 28593 R-HSA-5625574 https://reactome.org/PathwayBrowser/#/R-HSA-5625574 Defective SLC22A18 does not exchange extracellular organic cations for cytosolic H+ TAS Homo sapiens 28593 R-HSA-597628 https://reactome.org/PathwayBrowser/#/R-HSA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ TAS Homo sapiens 28593 R-MMU-597628 https://reactome.org/PathwayBrowser/#/R-MMU-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Mus musculus 28593 R-PFA-597628 https://reactome.org/PathwayBrowser/#/R-PFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Plasmodium falciparum 28593 R-RNO-597628 https://reactome.org/PathwayBrowser/#/R-RNO-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Rattus norvegicus 28593 R-SSC-597628 https://reactome.org/PathwayBrowser/#/R-SSC-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Sus scrofa 28593 R-XTR-597628 https://reactome.org/PathwayBrowser/#/R-XTR-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Xenopus tropicalis 28599 R-MTU-936703 https://reactome.org/PathwayBrowser/#/R-MTU-936703 sulfite is reduced to sulfide TAS Mycobacterium tuberculosis 28600 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 28600 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 28600 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 28600 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 28600 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 28600 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 28600 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 28600 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 28600 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 28602 R-BTA-5628905 https://reactome.org/PathwayBrowser/#/R-BTA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Bos taurus 28602 R-BTA-70262 https://reactome.org/PathwayBrowser/#/R-BTA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Bos taurus 28602 R-BTA-70467 https://reactome.org/PathwayBrowser/#/R-BTA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Bos taurus 28602 R-BTA-71802 https://reactome.org/PathwayBrowser/#/R-BTA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Bos taurus 28602 R-CEL-70262 https://reactome.org/PathwayBrowser/#/R-CEL-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Caenorhabditis elegans 28602 R-CEL-70467 https://reactome.org/PathwayBrowser/#/R-CEL-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Caenorhabditis elegans 28602 R-CEL-71802 https://reactome.org/PathwayBrowser/#/R-CEL-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Caenorhabditis elegans 28602 R-CFA-5628905 https://reactome.org/PathwayBrowser/#/R-CFA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Canis familiaris 28602 R-CFA-70262 https://reactome.org/PathwayBrowser/#/R-CFA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Canis familiaris 28602 R-CFA-70467 https://reactome.org/PathwayBrowser/#/R-CFA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Canis familiaris 28602 R-CFA-71802 https://reactome.org/PathwayBrowser/#/R-CFA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Canis familiaris 28602 R-DDI-70262 https://reactome.org/PathwayBrowser/#/R-DDI-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Dictyostelium discoideum 28602 R-DDI-71802 https://reactome.org/PathwayBrowser/#/R-DDI-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Dictyostelium discoideum 28602 R-DME-70262 https://reactome.org/PathwayBrowser/#/R-DME-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Drosophila melanogaster 28602 R-DME-70467 https://reactome.org/PathwayBrowser/#/R-DME-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Drosophila melanogaster 28602 R-DME-71802 https://reactome.org/PathwayBrowser/#/R-DME-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Drosophila melanogaster 28602 R-DRE-5628905 https://reactome.org/PathwayBrowser/#/R-DRE-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Danio rerio 28602 R-DRE-70467 https://reactome.org/PathwayBrowser/#/R-DRE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Danio rerio 28602 R-DRE-71802 https://reactome.org/PathwayBrowser/#/R-DRE-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Danio rerio 28602 R-GGA-352908 https://reactome.org/PathwayBrowser/#/R-GGA-352908 fructose 6-phosphate + ATP => fructose 2,6-bisphosphate + ADP TAS Gallus gallus 28602 R-GGA-352945 https://reactome.org/PathwayBrowser/#/R-GGA-352945 fructose 6-phosphate + ATP => fructose 1,6-bisphosphate + ADP TAS Gallus gallus 28602 R-GGA-372388 https://reactome.org/PathwayBrowser/#/R-GGA-372388 fructose 1,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate TAS Gallus gallus 28602 R-GGA-372425 https://reactome.org/PathwayBrowser/#/R-GGA-372425 fructose 2,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate TAS Gallus gallus 28602 R-GGA-5628905 https://reactome.org/PathwayBrowser/#/R-GGA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Gallus gallus 28602 R-GGA-70262 https://reactome.org/PathwayBrowser/#/R-GGA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Gallus gallus 28602 R-GGA-70467 https://reactome.org/PathwayBrowser/#/R-GGA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Gallus gallus 28602 R-GGA-71802 https://reactome.org/PathwayBrowser/#/R-GGA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Gallus gallus 28602 R-HSA-5628905 https://reactome.org/PathwayBrowser/#/R-HSA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate TAS Homo sapiens 28602 R-HSA-70262 https://reactome.org/PathwayBrowser/#/R-HSA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate TAS Homo sapiens 28602 R-HSA-70467 https://reactome.org/PathwayBrowser/#/R-HSA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP TAS Homo sapiens 28602 R-HSA-71802 https://reactome.org/PathwayBrowser/#/R-HSA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP TAS Homo sapiens 28602 R-MMU-5628905 https://reactome.org/PathwayBrowser/#/R-MMU-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Mus musculus 28602 R-MMU-70262 https://reactome.org/PathwayBrowser/#/R-MMU-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Mus musculus 28602 R-MMU-70467 https://reactome.org/PathwayBrowser/#/R-MMU-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Mus musculus 28602 R-MMU-71802 https://reactome.org/PathwayBrowser/#/R-MMU-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Mus musculus 28602 R-RNO-5628905 https://reactome.org/PathwayBrowser/#/R-RNO-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Rattus norvegicus 28602 R-RNO-70262 https://reactome.org/PathwayBrowser/#/R-RNO-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Rattus norvegicus 28602 R-RNO-70467 https://reactome.org/PathwayBrowser/#/R-RNO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Rattus norvegicus 28602 R-RNO-71802 https://reactome.org/PathwayBrowser/#/R-RNO-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Rattus norvegicus 28602 R-SCE-70262 https://reactome.org/PathwayBrowser/#/R-SCE-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Saccharomyces cerevisiae 28602 R-SCE-70467 https://reactome.org/PathwayBrowser/#/R-SCE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 28602 R-SCE-71802 https://reactome.org/PathwayBrowser/#/R-SCE-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 28602 R-SPO-70262 https://reactome.org/PathwayBrowser/#/R-SPO-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Schizosaccharomyces pombe 28602 R-SPO-70467 https://reactome.org/PathwayBrowser/#/R-SPO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 28602 R-SPO-71802 https://reactome.org/PathwayBrowser/#/R-SPO-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 28602 R-SSC-5628905 https://reactome.org/PathwayBrowser/#/R-SSC-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Sus scrofa 28602 R-SSC-70262 https://reactome.org/PathwayBrowser/#/R-SSC-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Sus scrofa 28602 R-SSC-70467 https://reactome.org/PathwayBrowser/#/R-SSC-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Sus scrofa 28602 R-SSC-71802 https://reactome.org/PathwayBrowser/#/R-SSC-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Sus scrofa 28602 R-XTR-5628905 https://reactome.org/PathwayBrowser/#/R-XTR-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Xenopus tropicalis 28602 R-XTR-71802 https://reactome.org/PathwayBrowser/#/R-XTR-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Xenopus tropicalis 28624 R-BTA-197958 https://reactome.org/PathwayBrowser/#/R-BTA-197958 FPGS-2 transforms THF to THFPG IEA Bos taurus 28624 R-BTA-200651 https://reactome.org/PathwayBrowser/#/R-BTA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Bos taurus 28624 R-BTA-200682 https://reactome.org/PathwayBrowser/#/R-BTA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Bos taurus 28624 R-BTA-200711 https://reactome.org/PathwayBrowser/#/R-BTA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Bos taurus 28624 R-BTA-200735 https://reactome.org/PathwayBrowser/#/R-BTA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Bos taurus 28624 R-BTA-6808487 https://reactome.org/PathwayBrowser/#/R-BTA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 28624 R-BTA-6808496 https://reactome.org/PathwayBrowser/#/R-BTA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 28624 R-CEL-197958 https://reactome.org/PathwayBrowser/#/R-CEL-197958 FPGS-2 transforms THF to THFPG IEA Caenorhabditis elegans 28624 R-CEL-200651 https://reactome.org/PathwayBrowser/#/R-CEL-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Caenorhabditis elegans 28624 R-CEL-200682 https://reactome.org/PathwayBrowser/#/R-CEL-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Caenorhabditis elegans 28624 R-CEL-200711 https://reactome.org/PathwayBrowser/#/R-CEL-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Caenorhabditis elegans 28624 R-CEL-200735 https://reactome.org/PathwayBrowser/#/R-CEL-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Caenorhabditis elegans 28624 R-CEL-6808487 https://reactome.org/PathwayBrowser/#/R-CEL-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 28624 R-CEL-6808496 https://reactome.org/PathwayBrowser/#/R-CEL-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 28624 R-CFA-197958 https://reactome.org/PathwayBrowser/#/R-CFA-197958 FPGS-2 transforms THF to THFPG IEA Canis familiaris 28624 R-CFA-200651 https://reactome.org/PathwayBrowser/#/R-CFA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Canis familiaris 28624 R-CFA-200682 https://reactome.org/PathwayBrowser/#/R-CFA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Canis familiaris 28624 R-CFA-200711 https://reactome.org/PathwayBrowser/#/R-CFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Canis familiaris 28624 R-CFA-200735 https://reactome.org/PathwayBrowser/#/R-CFA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Canis familiaris 28624 R-CFA-6808487 https://reactome.org/PathwayBrowser/#/R-CFA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 28624 R-CFA-6808496 https://reactome.org/PathwayBrowser/#/R-CFA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 28624 R-DDI-197958 https://reactome.org/PathwayBrowser/#/R-DDI-197958 FPGS-2 transforms THF to THFPG IEA Dictyostelium discoideum 28624 R-DDI-200651 https://reactome.org/PathwayBrowser/#/R-DDI-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Dictyostelium discoideum 28624 R-DDI-200682 https://reactome.org/PathwayBrowser/#/R-DDI-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Dictyostelium discoideum 28624 R-DDI-200711 https://reactome.org/PathwayBrowser/#/R-DDI-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Dictyostelium discoideum 28624 R-DDI-200735 https://reactome.org/PathwayBrowser/#/R-DDI-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Dictyostelium discoideum 28624 R-DME-197958 https://reactome.org/PathwayBrowser/#/R-DME-197958 FPGS-2 transforms THF to THFPG IEA Drosophila melanogaster 28624 R-DME-200651 https://reactome.org/PathwayBrowser/#/R-DME-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Drosophila melanogaster 28624 R-DME-200682 https://reactome.org/PathwayBrowser/#/R-DME-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Drosophila melanogaster 28624 R-DME-200711 https://reactome.org/PathwayBrowser/#/R-DME-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Drosophila melanogaster 28624 R-DME-200735 https://reactome.org/PathwayBrowser/#/R-DME-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Drosophila melanogaster 28624 R-DME-6808487 https://reactome.org/PathwayBrowser/#/R-DME-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 28624 R-DME-6808496 https://reactome.org/PathwayBrowser/#/R-DME-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 28624 R-DRE-197958 https://reactome.org/PathwayBrowser/#/R-DRE-197958 FPGS-2 transforms THF to THFPG IEA Danio rerio 28624 R-DRE-200651 https://reactome.org/PathwayBrowser/#/R-DRE-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Danio rerio 28624 R-DRE-200682 https://reactome.org/PathwayBrowser/#/R-DRE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Danio rerio 28624 R-DRE-200711 https://reactome.org/PathwayBrowser/#/R-DRE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Danio rerio 28624 R-DRE-200735 https://reactome.org/PathwayBrowser/#/R-DRE-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Danio rerio 28624 R-DRE-6808496 https://reactome.org/PathwayBrowser/#/R-DRE-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Danio rerio 28624 R-GGA-197958 https://reactome.org/PathwayBrowser/#/R-GGA-197958 FPGS-2 transforms THF to THFPG IEA Gallus gallus 28624 R-GGA-200651 https://reactome.org/PathwayBrowser/#/R-GGA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Gallus gallus 28624 R-GGA-200682 https://reactome.org/PathwayBrowser/#/R-GGA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Gallus gallus 28624 R-GGA-200711 https://reactome.org/PathwayBrowser/#/R-GGA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Gallus gallus 28624 R-GGA-200735 https://reactome.org/PathwayBrowser/#/R-GGA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Gallus gallus 28624 R-GGA-6808487 https://reactome.org/PathwayBrowser/#/R-GGA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Gallus gallus 28624 R-HSA-197958 https://reactome.org/PathwayBrowser/#/R-HSA-197958 FPGS-2 transforms THF to THFPG TAS Homo sapiens 28624 R-HSA-200651 https://reactome.org/PathwayBrowser/#/R-HSA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine TAS Homo sapiens 28624 R-HSA-200682 https://reactome.org/PathwayBrowser/#/R-HSA-200682 Mitochondrial FPGS-1 transforms THF to THFPG TAS Homo sapiens 28624 R-HSA-200711 https://reactome.org/PathwayBrowser/#/R-HSA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG TAS Homo sapiens 28624 R-HSA-200735 https://reactome.org/PathwayBrowser/#/R-HSA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG TAS Homo sapiens 28624 R-HSA-6808487 https://reactome.org/PathwayBrowser/#/R-HSA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 28624 R-HSA-6808496 https://reactome.org/PathwayBrowser/#/R-HSA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 28624 R-MMU-197958 https://reactome.org/PathwayBrowser/#/R-MMU-197958 FPGS-2 transforms THF to THFPG IEA Mus musculus 28624 R-MMU-200651 https://reactome.org/PathwayBrowser/#/R-MMU-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Mus musculus 28624 R-MMU-200682 https://reactome.org/PathwayBrowser/#/R-MMU-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Mus musculus 28624 R-MMU-200711 https://reactome.org/PathwayBrowser/#/R-MMU-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Mus musculus 28624 R-MMU-200735 https://reactome.org/PathwayBrowser/#/R-MMU-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Mus musculus 28624 R-MMU-6808487 https://reactome.org/PathwayBrowser/#/R-MMU-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 28624 R-MMU-6808496 https://reactome.org/PathwayBrowser/#/R-MMU-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 28624 R-PFA-200651 https://reactome.org/PathwayBrowser/#/R-PFA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Plasmodium falciparum 28624 R-PFA-200711 https://reactome.org/PathwayBrowser/#/R-PFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Plasmodium falciparum 28624 R-PFA-200735 https://reactome.org/PathwayBrowser/#/R-PFA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Plasmodium falciparum 28624 R-RNO-197958 https://reactome.org/PathwayBrowser/#/R-RNO-197958 FPGS-2 transforms THF to THFPG IEA Rattus norvegicus 28624 R-RNO-200651 https://reactome.org/PathwayBrowser/#/R-RNO-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Rattus norvegicus 28624 R-RNO-200682 https://reactome.org/PathwayBrowser/#/R-RNO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Rattus norvegicus 28624 R-RNO-200711 https://reactome.org/PathwayBrowser/#/R-RNO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Rattus norvegicus 28624 R-RNO-200735 https://reactome.org/PathwayBrowser/#/R-RNO-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Rattus norvegicus 28624 R-RNO-6808487 https://reactome.org/PathwayBrowser/#/R-RNO-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 28624 R-RNO-6808496 https://reactome.org/PathwayBrowser/#/R-RNO-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 28624 R-SCE-197958 https://reactome.org/PathwayBrowser/#/R-SCE-197958 FPGS-2 transforms THF to THFPG IEA Saccharomyces cerevisiae 28624 R-SCE-200682 https://reactome.org/PathwayBrowser/#/R-SCE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Saccharomyces cerevisiae 28624 R-SCE-200711 https://reactome.org/PathwayBrowser/#/R-SCE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Saccharomyces cerevisiae 28624 R-SPO-197958 https://reactome.org/PathwayBrowser/#/R-SPO-197958 FPGS-2 transforms THF to THFPG IEA Schizosaccharomyces pombe 28624 R-SPO-200682 https://reactome.org/PathwayBrowser/#/R-SPO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Schizosaccharomyces pombe 28624 R-SPO-200711 https://reactome.org/PathwayBrowser/#/R-SPO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Schizosaccharomyces pombe 28624 R-SSC-197958 https://reactome.org/PathwayBrowser/#/R-SSC-197958 FPGS-2 transforms THF to THFPG IEA Sus scrofa 28624 R-SSC-200651 https://reactome.org/PathwayBrowser/#/R-SSC-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Sus scrofa 28624 R-SSC-200682 https://reactome.org/PathwayBrowser/#/R-SSC-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Sus scrofa 28624 R-SSC-200711 https://reactome.org/PathwayBrowser/#/R-SSC-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Sus scrofa 28624 R-SSC-200735 https://reactome.org/PathwayBrowser/#/R-SSC-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Sus scrofa 28624 R-SSC-6808487 https://reactome.org/PathwayBrowser/#/R-SSC-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 28624 R-SSC-6808496 https://reactome.org/PathwayBrowser/#/R-SSC-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 28624 R-XTR-197958 https://reactome.org/PathwayBrowser/#/R-XTR-197958 FPGS-2 transforms THF to THFPG IEA Xenopus tropicalis 28624 R-XTR-200651 https://reactome.org/PathwayBrowser/#/R-XTR-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Xenopus tropicalis 28624 R-XTR-200682 https://reactome.org/PathwayBrowser/#/R-XTR-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Xenopus tropicalis 28624 R-XTR-200711 https://reactome.org/PathwayBrowser/#/R-XTR-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Xenopus tropicalis 28624 R-XTR-200735 https://reactome.org/PathwayBrowser/#/R-XTR-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Xenopus tropicalis 28624 R-XTR-6808487 https://reactome.org/PathwayBrowser/#/R-XTR-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 28624 R-XTR-6808496 https://reactome.org/PathwayBrowser/#/R-XTR-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 28632 R-BTA-77331 https://reactome.org/PathwayBrowser/#/R-BTA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Bos taurus 28632 R-BTA-77333 https://reactome.org/PathwayBrowser/#/R-BTA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Bos taurus 28632 R-CEL-77331 https://reactome.org/PathwayBrowser/#/R-CEL-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Caenorhabditis elegans 28632 R-CEL-77333 https://reactome.org/PathwayBrowser/#/R-CEL-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Caenorhabditis elegans 28632 R-CFA-77331 https://reactome.org/PathwayBrowser/#/R-CFA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Canis familiaris 28632 R-CFA-77333 https://reactome.org/PathwayBrowser/#/R-CFA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Canis familiaris 28632 R-DDI-77333 https://reactome.org/PathwayBrowser/#/R-DDI-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Dictyostelium discoideum 28632 R-DME-77333 https://reactome.org/PathwayBrowser/#/R-DME-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Drosophila melanogaster 28632 R-DRE-77331 https://reactome.org/PathwayBrowser/#/R-DRE-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Danio rerio 28632 R-GGA-77331 https://reactome.org/PathwayBrowser/#/R-GGA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Gallus gallus 28632 R-HSA-77331 https://reactome.org/PathwayBrowser/#/R-HSA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H TAS Homo sapiens 28632 R-HSA-77333 https://reactome.org/PathwayBrowser/#/R-HSA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA TAS Homo sapiens 28632 R-MMU-77331 https://reactome.org/PathwayBrowser/#/R-MMU-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Mus musculus 28632 R-MMU-77333 https://reactome.org/PathwayBrowser/#/R-MMU-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Mus musculus 28632 R-RNO-77331 https://reactome.org/PathwayBrowser/#/R-RNO-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Rattus norvegicus 28632 R-RNO-77333 https://reactome.org/PathwayBrowser/#/R-RNO-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Rattus norvegicus 28632 R-SSC-77331 https://reactome.org/PathwayBrowser/#/R-SSC-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Sus scrofa 28632 R-SSC-77333 https://reactome.org/PathwayBrowser/#/R-SSC-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Sus scrofa 28632 R-XTR-77331 https://reactome.org/PathwayBrowser/#/R-XTR-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Xenopus tropicalis 28632 R-XTR-77333 https://reactome.org/PathwayBrowser/#/R-XTR-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Xenopus tropicalis 28640 R-BTA-166726 https://reactome.org/PathwayBrowser/#/R-BTA-166726 Activation of MASPs IEA Bos taurus 28640 R-BTA-166753 https://reactome.org/PathwayBrowser/#/R-BTA-166753 Conversion of C4 into C4a and C4b IEA Bos taurus 28640 R-BTA-166792 https://reactome.org/PathwayBrowser/#/R-BTA-166792 Conversion of C2 into C2a and C2b IEA Bos taurus 28640 R-BTA-2203480 https://reactome.org/PathwayBrowser/#/R-BTA-2203480 COLEC11 binds ligands IEA Bos taurus 28640 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 28640 R-BTA-2855054 https://reactome.org/PathwayBrowser/#/R-BTA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Bos taurus 28640 R-BTA-6804099 https://reactome.org/PathwayBrowser/#/R-BTA-6804099 HMGB1 binds LTP IEA Bos taurus 28640 R-CEL-6804099 https://reactome.org/PathwayBrowser/#/R-CEL-6804099 HMGB1 binds LTP IEA Caenorhabditis elegans 28640 R-CFA-166726 https://reactome.org/PathwayBrowser/#/R-CFA-166726 Activation of MASPs IEA Canis familiaris 28640 R-CFA-166753 https://reactome.org/PathwayBrowser/#/R-CFA-166753 Conversion of C4 into C4a and C4b IEA Canis familiaris 28640 R-CFA-166792 https://reactome.org/PathwayBrowser/#/R-CFA-166792 Conversion of C2 into C2a and C2b IEA Canis familiaris 28640 R-CFA-2247510 https://reactome.org/PathwayBrowser/#/R-CFA-2247510 MARCO:ligand is endocytosed IEA Canis familiaris 28640 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 28640 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 28640 R-CFA-2855054 https://reactome.org/PathwayBrowser/#/R-CFA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Canis familiaris 28640 R-CFA-6804099 https://reactome.org/PathwayBrowser/#/R-CFA-6804099 HMGB1 binds LTP IEA Canis familiaris 28640 R-DDI-6804099 https://reactome.org/PathwayBrowser/#/R-DDI-6804099 HMGB1 binds LTP IEA Dictyostelium discoideum 28640 R-DME-6804099 https://reactome.org/PathwayBrowser/#/R-DME-6804099 HMGB1 binds LTP IEA Drosophila melanogaster 28640 R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 28640 R-DRE-6804099 https://reactome.org/PathwayBrowser/#/R-DRE-6804099 HMGB1 binds LTP IEA Danio rerio 28640 R-GGA-166726 https://reactome.org/PathwayBrowser/#/R-GGA-166726 Activation of MASPs IEA Gallus gallus 28640 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus 28640 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus 28640 R-GGA-2203480 https://reactome.org/PathwayBrowser/#/R-GGA-2203480 COLEC11 binds ligands IEA Gallus gallus 28640 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 28640 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 28640 R-GGA-2855054 https://reactome.org/PathwayBrowser/#/R-GGA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Gallus gallus 28640 R-GGA-6804099 https://reactome.org/PathwayBrowser/#/R-GGA-6804099 HMGB1 binds LTP IEA Gallus gallus 28640 R-HSA-166072 https://reactome.org/PathwayBrowser/#/R-HSA-166072 MyD88 forms a complex with TIRAP:activated TLR2/4 TAS Homo sapiens 28640 R-HSA-166082 https://reactome.org/PathwayBrowser/#/R-HSA-166082 IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex TAS Homo sapiens 28640 R-HSA-166091 https://reactome.org/PathwayBrowser/#/R-HSA-166091 IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex TAS Homo sapiens 28640 R-HSA-166119 https://reactome.org/PathwayBrowser/#/R-HSA-166119 First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal TAS Homo sapiens 28640 R-HSA-166284 https://reactome.org/PathwayBrowser/#/R-HSA-166284 Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP TAS Homo sapiens 28640 R-HSA-166286 https://reactome.org/PathwayBrowser/#/R-HSA-166286 Multiple IRAK1 autophosphorylation steps TAS Homo sapiens 28640 R-HSA-166362 https://reactome.org/PathwayBrowser/#/R-HSA-166362 Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 28640 R-HSA-166363 https://reactome.org/PathwayBrowser/#/R-HSA-166363 TRAF6 binds to hp- IRAK1 TAS Homo sapiens 28640 R-HSA-166726 https://reactome.org/PathwayBrowser/#/R-HSA-166726 Activation of MASPs TAS Homo sapiens 28640 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens 28640 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens 28640 R-HSA-168950 https://reactome.org/PathwayBrowser/#/R-HSA-168950 TLR6:TLR2 is recruited to ligand:CD14:CD36 TAS Homo sapiens 28640 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 28640 R-HSA-2173781 https://reactome.org/PathwayBrowser/#/R-HSA-2173781 MARCO (SCARA2) binds ligands IEA Homo sapiens 28640 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 28640 R-HSA-2201316 https://reactome.org/PathwayBrowser/#/R-HSA-2201316 Activated TLR2/4 interacts with MAL (TIRAP) TAS Homo sapiens 28640 R-HSA-2201322 https://reactome.org/PathwayBrowser/#/R-HSA-2201322 TIRAP is phosphorylated by BTK TAS Homo sapiens 28640 R-HSA-2203480 https://reactome.org/PathwayBrowser/#/R-HSA-2203480 COLEC11 binds ligands TAS Homo sapiens 28640 R-HSA-2247510 https://reactome.org/PathwayBrowser/#/R-HSA-2247510 MARCO:ligand is endocytosed TAS Homo sapiens 28640 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 28640 R-HSA-2262775 https://reactome.org/PathwayBrowser/#/R-HSA-2262775 Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 28640 R-HSA-2262777 https://reactome.org/PathwayBrowser/#/R-HSA-2262777 TRAF6 binds to p-IRAK2 TAS Homo sapiens 28640 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 28640 R-HSA-2559414 https://reactome.org/PathwayBrowser/#/R-HSA-2559414 Activated TLR2/4:TIRAP interacts with BTK TAS Homo sapiens 28640 R-HSA-2559464 https://reactome.org/PathwayBrowser/#/R-HSA-2559464 TLR6/2 ligand associates with CD14 and CD36 within lipid rafts TAS Homo sapiens 28640 R-HSA-2855054 https://reactome.org/PathwayBrowser/#/R-HSA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface TAS Homo sapiens 28640 R-HSA-5602353 https://reactome.org/PathwayBrowser/#/R-HSA-5602353 Defective IRAK4 variants do not bind MyD88:MAL:BTK:activated TLR2/4 TAS Homo sapiens 28640 R-HSA-5602383 https://reactome.org/PathwayBrowser/#/R-HSA-5602383 Defective MyD88 does not oligomerize within the activated TLR2/4 complex TAS Homo sapiens 28640 R-HSA-5602606 https://reactome.org/PathwayBrowser/#/R-HSA-5602606 Defective MyD88 does not bind MAL(TIRAP):TLR2/4 TAS Homo sapiens 28640 R-HSA-5602672 https://reactome.org/PathwayBrowser/#/R-HSA-5602672 Defective IRAK4 does not bind MyD88 within the TLR2/4 complex TAS Homo sapiens 28640 R-HSA-6804099 https://reactome.org/PathwayBrowser/#/R-HSA-6804099 HMGB1 binds LTP TAS Homo sapiens 28640 R-HSA-8863895 https://reactome.org/PathwayBrowser/#/R-HSA-8863895 IKKB phosphorylates SNAP23 TAS Homo sapiens 28640 R-HSA-937022 https://reactome.org/PathwayBrowser/#/R-HSA-937022 IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP TAS Homo sapiens 28640 R-HSA-937059 https://reactome.org/PathwayBrowser/#/R-HSA-937059 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex TAS Homo sapiens 28640 R-HSA-937079 https://reactome.org/PathwayBrowser/#/R-HSA-937079 MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 TAS Homo sapiens 28640 R-MMU-166726 https://reactome.org/PathwayBrowser/#/R-MMU-166726 Activation of MASPs IEA Mus musculus 28640 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus 28640 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus 28640 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 28640 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 28640 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 28640 R-MMU-2203480 https://reactome.org/PathwayBrowser/#/R-MMU-2203480 COLEC11 binds ligands IEA Mus musculus 28640 R-MMU-2247510 https://reactome.org/PathwayBrowser/#/R-MMU-2247510 MARCO:ligand is endocytosed IEA Mus musculus 28640 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 28640 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 28640 R-MMU-2855054 https://reactome.org/PathwayBrowser/#/R-MMU-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Mus musculus 28640 R-MMU-6804099 https://reactome.org/PathwayBrowser/#/R-MMU-6804099 HMGB1 binds LTP IEA Mus musculus 28640 R-PFA-6804099 https://reactome.org/PathwayBrowser/#/R-PFA-6804099 HMGB1 binds LTP IEA Plasmodium falciparum 28640 R-RNO-166726 https://reactome.org/PathwayBrowser/#/R-RNO-166726 Activation of MASPs IEA Rattus norvegicus 28640 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus 28640 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus 28640 R-RNO-2247510 https://reactome.org/PathwayBrowser/#/R-RNO-2247510 MARCO:ligand is endocytosed IEA Rattus norvegicus 28640 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 28640 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 28640 R-RNO-2855054 https://reactome.org/PathwayBrowser/#/R-RNO-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Rattus norvegicus 28640 R-RNO-6804099 https://reactome.org/PathwayBrowser/#/R-RNO-6804099 HMGB1 binds LTP IEA Rattus norvegicus 28640 R-SCE-6804099 https://reactome.org/PathwayBrowser/#/R-SCE-6804099 HMGB1 binds LTP IEA Saccharomyces cerevisiae 28640 R-SPO-6804099 https://reactome.org/PathwayBrowser/#/R-SPO-6804099 HMGB1 binds LTP IEA Schizosaccharomyces pombe 28640 R-SSC-166726 https://reactome.org/PathwayBrowser/#/R-SSC-166726 Activation of MASPs IEA Sus scrofa 28640 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa 28640 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa 28640 R-SSC-2203480 https://reactome.org/PathwayBrowser/#/R-SSC-2203480 COLEC11 binds ligands IEA Sus scrofa 28640 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 28640 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 28640 R-SSC-2855054 https://reactome.org/PathwayBrowser/#/R-SSC-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Sus scrofa 28640 R-XTR-166726 https://reactome.org/PathwayBrowser/#/R-XTR-166726 Activation of MASPs IEA Xenopus tropicalis 28640 R-XTR-166753 https://reactome.org/PathwayBrowser/#/R-XTR-166753 Conversion of C4 into C4a and C4b IEA Xenopus tropicalis 28640 R-XTR-166792 https://reactome.org/PathwayBrowser/#/R-XTR-166792 Conversion of C2 into C2a and C2b IEA Xenopus tropicalis 28640 R-XTR-2855054 https://reactome.org/PathwayBrowser/#/R-XTR-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Xenopus tropicalis 28640 R-XTR-6804099 https://reactome.org/PathwayBrowser/#/R-XTR-6804099 HMGB1 binds LTP IEA Xenopus tropicalis 28645 R-BTA-70333 https://reactome.org/PathwayBrowser/#/R-BTA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Bos taurus 28645 R-DDI-70333 https://reactome.org/PathwayBrowser/#/R-DDI-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Dictyostelium discoideum 28645 R-DME-70333 https://reactome.org/PathwayBrowser/#/R-DME-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Drosophila melanogaster 28645 R-GGA-70333 https://reactome.org/PathwayBrowser/#/R-GGA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Gallus gallus 28645 R-HSA-70333 https://reactome.org/PathwayBrowser/#/R-HSA-70333 KHK dimer phosphorylates Fru to Fru 1-P TAS Homo sapiens 28645 R-MMU-70333 https://reactome.org/PathwayBrowser/#/R-MMU-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Mus musculus 28645 R-RNO-70333 https://reactome.org/PathwayBrowser/#/R-RNO-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Rattus norvegicus 28645 R-SSC-70333 https://reactome.org/PathwayBrowser/#/R-SSC-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Sus scrofa 28648 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 28648 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 28648 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 28648 R-HSA-5250600 https://reactome.org/PathwayBrowser/#/R-HSA-5250600 botD:SV2:GD2 internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 28648 R-HSA-5250607 https://reactome.org/PathwayBrowser/#/R-HSA-5250607 botD HC:LC binds SV2A or B or C and GD2 on the target cell surface TAS Homo sapiens 28648 R-HSA-5250616 https://reactome.org/PathwayBrowser/#/R-HSA-5250616 botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 28648 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 28648 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 28648 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 28648 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 28648 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 28648 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 28654 R-BTA-508179 https://reactome.org/PathwayBrowser/#/R-BTA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Bos taurus 28654 R-BTA-508189 https://reactome.org/PathwayBrowser/#/R-BTA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Bos taurus 28654 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 28654 R-BTA-70723 https://reactome.org/PathwayBrowser/#/R-BTA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Bos taurus 28654 R-BTA-70724 https://reactome.org/PathwayBrowser/#/R-BTA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Bos taurus 28654 R-CEL-508179 https://reactome.org/PathwayBrowser/#/R-CEL-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Caenorhabditis elegans 28654 R-CEL-508189 https://reactome.org/PathwayBrowser/#/R-CEL-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Caenorhabditis elegans 28654 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 28654 R-CEL-70723 https://reactome.org/PathwayBrowser/#/R-CEL-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Caenorhabditis elegans 28654 R-CEL-70724 https://reactome.org/PathwayBrowser/#/R-CEL-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Caenorhabditis elegans 28654 R-CFA-508179 https://reactome.org/PathwayBrowser/#/R-CFA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Canis familiaris 28654 R-CFA-508189 https://reactome.org/PathwayBrowser/#/R-CFA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Canis familiaris 28654 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 28654 R-CFA-70723 https://reactome.org/PathwayBrowser/#/R-CFA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Canis familiaris 28654 R-CFA-70724 https://reactome.org/PathwayBrowser/#/R-CFA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Canis familiaris 28654 R-DDI-508179 https://reactome.org/PathwayBrowser/#/R-DDI-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Dictyostelium discoideum 28654 R-DDI-508189 https://reactome.org/PathwayBrowser/#/R-DDI-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Dictyostelium discoideum 28654 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 28654 R-DDI-70723 https://reactome.org/PathwayBrowser/#/R-DDI-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Dictyostelium discoideum 28654 R-DDI-70724 https://reactome.org/PathwayBrowser/#/R-DDI-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Dictyostelium discoideum 28654 R-DME-508179 https://reactome.org/PathwayBrowser/#/R-DME-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Drosophila melanogaster 28654 R-DME-508189 https://reactome.org/PathwayBrowser/#/R-DME-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Drosophila melanogaster 28654 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 28654 R-DME-70723 https://reactome.org/PathwayBrowser/#/R-DME-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Drosophila melanogaster 28654 R-DME-70724 https://reactome.org/PathwayBrowser/#/R-DME-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Drosophila melanogaster 28654 R-DRE-508179 https://reactome.org/PathwayBrowser/#/R-DRE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Danio rerio 28654 R-DRE-508189 https://reactome.org/PathwayBrowser/#/R-DRE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Danio rerio 28654 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 28654 R-DRE-70723 https://reactome.org/PathwayBrowser/#/R-DRE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Danio rerio 28654 R-DRE-70724 https://reactome.org/PathwayBrowser/#/R-DRE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Danio rerio 28654 R-GGA-508189 https://reactome.org/PathwayBrowser/#/R-GGA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Gallus gallus 28654 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 28654 R-GGA-70723 https://reactome.org/PathwayBrowser/#/R-GGA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Gallus gallus 28654 R-HSA-508179 https://reactome.org/PathwayBrowser/#/R-HSA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] TAS Homo sapiens 28654 R-HSA-508189 https://reactome.org/PathwayBrowser/#/R-HSA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] TAS Homo sapiens 28654 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 28654 R-HSA-70723 https://reactome.org/PathwayBrowser/#/R-HSA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] TAS Homo sapiens 28654 R-HSA-70724 https://reactome.org/PathwayBrowser/#/R-HSA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] TAS Homo sapiens 28654 R-MMU-508179 https://reactome.org/PathwayBrowser/#/R-MMU-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Mus musculus 28654 R-MMU-508189 https://reactome.org/PathwayBrowser/#/R-MMU-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Mus musculus 28654 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 28654 R-MMU-70723 https://reactome.org/PathwayBrowser/#/R-MMU-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Mus musculus 28654 R-MMU-70724 https://reactome.org/PathwayBrowser/#/R-MMU-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Mus musculus 28654 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 28654 R-RNO-508179 https://reactome.org/PathwayBrowser/#/R-RNO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Rattus norvegicus 28654 R-RNO-508189 https://reactome.org/PathwayBrowser/#/R-RNO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Rattus norvegicus 28654 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 28654 R-RNO-70723 https://reactome.org/PathwayBrowser/#/R-RNO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Rattus norvegicus 28654 R-RNO-70724 https://reactome.org/PathwayBrowser/#/R-RNO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Rattus norvegicus 28654 R-SCE-508179 https://reactome.org/PathwayBrowser/#/R-SCE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Saccharomyces cerevisiae 28654 R-SCE-508189 https://reactome.org/PathwayBrowser/#/R-SCE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Saccharomyces cerevisiae 28654 R-SCE-70723 https://reactome.org/PathwayBrowser/#/R-SCE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Saccharomyces cerevisiae 28654 R-SCE-70724 https://reactome.org/PathwayBrowser/#/R-SCE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Saccharomyces cerevisiae 28654 R-SPO-508179 https://reactome.org/PathwayBrowser/#/R-SPO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Schizosaccharomyces pombe 28654 R-SPO-508189 https://reactome.org/PathwayBrowser/#/R-SPO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Schizosaccharomyces pombe 28654 R-SPO-70723 https://reactome.org/PathwayBrowser/#/R-SPO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Schizosaccharomyces pombe 28654 R-SPO-70724 https://reactome.org/PathwayBrowser/#/R-SPO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Schizosaccharomyces pombe 28654 R-SSC-508179 https://reactome.org/PathwayBrowser/#/R-SSC-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Sus scrofa 28654 R-SSC-508189 https://reactome.org/PathwayBrowser/#/R-SSC-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Sus scrofa 28654 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 28654 R-SSC-70723 https://reactome.org/PathwayBrowser/#/R-SSC-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Sus scrofa 28654 R-SSC-70724 https://reactome.org/PathwayBrowser/#/R-SSC-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Sus scrofa 28654 R-XTR-508179 https://reactome.org/PathwayBrowser/#/R-XTR-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Xenopus tropicalis 28654 R-XTR-508189 https://reactome.org/PathwayBrowser/#/R-XTR-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Xenopus tropicalis 28654 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 28654 R-XTR-70723 https://reactome.org/PathwayBrowser/#/R-XTR-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Xenopus tropicalis 28654 R-XTR-70724 https://reactome.org/PathwayBrowser/#/R-XTR-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Xenopus tropicalis 28661 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 28661 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 28661 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 28661 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 28661 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 28661 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 28661 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 28661 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 28661 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 28661 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 28661 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 28661 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 28661 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 28661 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 28661 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 28661 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 28661 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 28661 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 28661 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 28661 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 28661 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 28661 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 28661 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 28661 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 28661 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 28661 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 28661 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 28661 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 28661 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 28661 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 28661 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 28661 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 28661 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 28661 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 28661 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 28666 R-BTA-266012 https://reactome.org/PathwayBrowser/#/R-BTA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Bos taurus 28666 R-BTA-266046 https://reactome.org/PathwayBrowser/#/R-BTA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Bos taurus 28666 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 28666 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 28666 R-BTA-391937 https://reactome.org/PathwayBrowser/#/R-BTA-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Bos taurus 28666 R-BTA-391943 https://reactome.org/PathwayBrowser/#/R-BTA-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Bos taurus 28666 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 28666 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 28666 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 28666 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 28666 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 28666 R-CEL-266046 https://reactome.org/PathwayBrowser/#/R-CEL-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Caenorhabditis elegans 28666 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 28666 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 28666 R-CEL-391937 https://reactome.org/PathwayBrowser/#/R-CEL-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Caenorhabditis elegans 28666 R-CEL-391943 https://reactome.org/PathwayBrowser/#/R-CEL-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 28666 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 28666 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 28666 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 28666 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 28666 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 28666 R-CFA-266012 https://reactome.org/PathwayBrowser/#/R-CFA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Canis familiaris 28666 R-CFA-266046 https://reactome.org/PathwayBrowser/#/R-CFA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Canis familiaris 28666 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 28666 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 28666 R-CFA-391937 https://reactome.org/PathwayBrowser/#/R-CFA-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Canis familiaris 28666 R-CFA-391943 https://reactome.org/PathwayBrowser/#/R-CFA-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Canis familiaris 28666 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 28666 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 28666 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 28666 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 28666 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 28666 R-DME-266012 https://reactome.org/PathwayBrowser/#/R-DME-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Drosophila melanogaster 28666 R-DME-266046 https://reactome.org/PathwayBrowser/#/R-DME-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Drosophila melanogaster 28666 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 28666 R-DME-391943 https://reactome.org/PathwayBrowser/#/R-DME-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 28666 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 28666 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 28666 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 28666 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 28666 R-DRE-391943 https://reactome.org/PathwayBrowser/#/R-DRE-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Danio rerio 28666 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 28666 R-GGA-266012 https://reactome.org/PathwayBrowser/#/R-GGA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Gallus gallus 28666 R-GGA-266046 https://reactome.org/PathwayBrowser/#/R-GGA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Gallus gallus 28666 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 28666 R-GGA-391943 https://reactome.org/PathwayBrowser/#/R-GGA-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Gallus gallus 28666 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 28666 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 28666 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 28666 R-HSA-266012 https://reactome.org/PathwayBrowser/#/R-HSA-266012 LTD4 is converted to LTE4 by DPEP1/2 TAS Homo sapiens 28666 R-HSA-266046 https://reactome.org/PathwayBrowser/#/R-HSA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 TAS Homo sapiens 28666 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 28666 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 28666 R-HSA-391937 https://reactome.org/PathwayBrowser/#/R-HSA-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes TAS Homo sapiens 28666 R-HSA-391943 https://reactome.org/PathwayBrowser/#/R-HSA-391943 CYSLT2 binds LTC4,LTD4,LTE4 TAS Homo sapiens 28666 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 28666 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 28666 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 28666 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 28666 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 28666 R-MMU-266012 https://reactome.org/PathwayBrowser/#/R-MMU-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Mus musculus 28666 R-MMU-266046 https://reactome.org/PathwayBrowser/#/R-MMU-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Mus musculus 28666 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 28666 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 28666 R-MMU-391937 https://reactome.org/PathwayBrowser/#/R-MMU-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Mus musculus 28666 R-MMU-391943 https://reactome.org/PathwayBrowser/#/R-MMU-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Mus musculus 28666 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 28666 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 28666 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 28666 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 28666 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 28666 R-RNO-266012 https://reactome.org/PathwayBrowser/#/R-RNO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Rattus norvegicus 28666 R-RNO-266046 https://reactome.org/PathwayBrowser/#/R-RNO-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Rattus norvegicus 28666 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 28666 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 28666 R-RNO-391937 https://reactome.org/PathwayBrowser/#/R-RNO-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Rattus norvegicus 28666 R-RNO-391943 https://reactome.org/PathwayBrowser/#/R-RNO-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 28666 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 28666 R-SCE-266046 https://reactome.org/PathwayBrowser/#/R-SCE-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Saccharomyces cerevisiae 28666 R-SPO-266012 https://reactome.org/PathwayBrowser/#/R-SPO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Schizosaccharomyces pombe 28666 R-SPO-266046 https://reactome.org/PathwayBrowser/#/R-SPO-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Schizosaccharomyces pombe 28666 R-SSC-266012 https://reactome.org/PathwayBrowser/#/R-SSC-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Sus scrofa 28666 R-SSC-266046 https://reactome.org/PathwayBrowser/#/R-SSC-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Sus scrofa 28666 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 28666 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 28666 R-SSC-391937 https://reactome.org/PathwayBrowser/#/R-SSC-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes IEA Sus scrofa 28666 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 28666 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 28666 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 28666 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 28666 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 28666 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 28667 R-HSA-2161732 https://reactome.org/PathwayBrowser/#/R-HSA-2161732 TXB2 is converted to 11dh-TXB2 by TXDH TAS Homo sapiens 28689 R-BTA-176631 https://reactome.org/PathwayBrowser/#/R-BTA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Bos taurus 28689 R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 28689 R-BTA-193073 https://reactome.org/PathwayBrowser/#/R-BTA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Bos taurus 28689 R-CFA-176631 https://reactome.org/PathwayBrowser/#/R-CFA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Canis familiaris 28689 R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 28689 R-CFA-193073 https://reactome.org/PathwayBrowser/#/R-CFA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Canis familiaris 28689 R-DME-176631 https://reactome.org/PathwayBrowser/#/R-DME-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Drosophila melanogaster 28689 R-DRE-176631 https://reactome.org/PathwayBrowser/#/R-DRE-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Danio rerio 28689 R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 28689 R-DRE-193073 https://reactome.org/PathwayBrowser/#/R-DRE-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Danio rerio 28689 R-GGA-176631 https://reactome.org/PathwayBrowser/#/R-GGA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Gallus gallus 28689 R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 28689 R-GGA-193073 https://reactome.org/PathwayBrowser/#/R-GGA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Gallus gallus 28689 R-HSA-176631 https://reactome.org/PathwayBrowser/#/R-HSA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP TAS Homo sapiens 28689 R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 28689 R-HSA-193073 https://reactome.org/PathwayBrowser/#/R-HSA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST TAS Homo sapiens 28689 R-MMU-176631 https://reactome.org/PathwayBrowser/#/R-MMU-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Mus musculus 28689 R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 28689 R-MMU-193073 https://reactome.org/PathwayBrowser/#/R-MMU-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Mus musculus 28689 R-RNO-176631 https://reactome.org/PathwayBrowser/#/R-RNO-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Rattus norvegicus 28689 R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 28689 R-RNO-193073 https://reactome.org/PathwayBrowser/#/R-RNO-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Rattus norvegicus 28689 R-SSC-176631 https://reactome.org/PathwayBrowser/#/R-SSC-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Sus scrofa 28689 R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 28689 R-SSC-193073 https://reactome.org/PathwayBrowser/#/R-SSC-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Sus scrofa 28689 R-XTR-176631 https://reactome.org/PathwayBrowser/#/R-XTR-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Xenopus tropicalis 28689 R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 28694 R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 28694 R-BTA-209891 https://reactome.org/PathwayBrowser/#/R-BTA-209891 Dopamine is oxidised to noradrenaline IEA Bos taurus 28694 R-BTA-442368 https://reactome.org/PathwayBrowser/#/R-BTA-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Bos taurus 28694 R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 28694 R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 28694 R-BTA-917933 https://reactome.org/PathwayBrowser/#/R-BTA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Bos taurus 28694 R-BTA-9709406 https://reactome.org/PathwayBrowser/#/R-BTA-9709406 CO binds to Cytochrome c oxidase IEA Bos taurus 28694 R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 28694 R-CFA-209891 https://reactome.org/PathwayBrowser/#/R-CFA-209891 Dopamine is oxidised to noradrenaline IEA Canis familiaris 28694 R-CFA-442368 https://reactome.org/PathwayBrowser/#/R-CFA-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Canis familiaris 28694 R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 28694 R-CFA-917933 https://reactome.org/PathwayBrowser/#/R-CFA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Canis familiaris 28694 R-CFA-9709406 https://reactome.org/PathwayBrowser/#/R-CFA-9709406 CO binds to Cytochrome c oxidase IEA Canis familiaris 28694 R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 28694 R-DME-209891 https://reactome.org/PathwayBrowser/#/R-DME-209891 Dopamine is oxidised to noradrenaline IEA Drosophila melanogaster 28694 R-DME-9709406 https://reactome.org/PathwayBrowser/#/R-DME-9709406 CO binds to Cytochrome c oxidase IEA Drosophila melanogaster 28694 R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 28694 R-DRE-209891 https://reactome.org/PathwayBrowser/#/R-DRE-209891 Dopamine is oxidised to noradrenaline IEA Danio rerio 28694 R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 28694 R-DRE-9709406 https://reactome.org/PathwayBrowser/#/R-DRE-9709406 CO binds to Cytochrome c oxidase IEA Danio rerio 28694 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 28694 R-GGA-209891 https://reactome.org/PathwayBrowser/#/R-GGA-209891 Dopamine is oxidised to noradrenaline IEA Gallus gallus 28694 R-GGA-442368 https://reactome.org/PathwayBrowser/#/R-GGA-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Gallus gallus 28694 R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 28694 R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 28694 R-GGA-917933 https://reactome.org/PathwayBrowser/#/R-GGA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Gallus gallus 28694 R-GGA-9709406 https://reactome.org/PathwayBrowser/#/R-GGA-9709406 CO binds to Cytochrome c oxidase IEA Gallus gallus 28694 R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 28694 R-HSA-209891 https://reactome.org/PathwayBrowser/#/R-HSA-209891 Dopamine is oxidised to noradrenaline TAS Homo sapiens 28694 R-HSA-442368 https://reactome.org/PathwayBrowser/#/R-HSA-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region TAS Homo sapiens 28694 R-HSA-5655760 https://reactome.org/PathwayBrowser/#/R-HSA-5655760 Defective SLC40A1 does not transport Fe3+ from extracellular region to cytosol TAS Homo sapiens 28694 R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 28694 R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 28694 R-HSA-917933 https://reactome.org/PathwayBrowser/#/R-HSA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ TAS Homo sapiens 28694 R-HSA-9709406 https://reactome.org/PathwayBrowser/#/R-HSA-9709406 CO binds to Cytochrome c oxidase TAS Homo sapiens 28694 R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 28694 R-MMU-209891 https://reactome.org/PathwayBrowser/#/R-MMU-209891 Dopamine is oxidised to noradrenaline IEA Mus musculus 28694 R-MMU-442368 https://reactome.org/PathwayBrowser/#/R-MMU-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Mus musculus 28694 R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 28694 R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 28694 R-MMU-917933 https://reactome.org/PathwayBrowser/#/R-MMU-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Mus musculus 28694 R-MMU-9709406 https://reactome.org/PathwayBrowser/#/R-MMU-9709406 CO binds to Cytochrome c oxidase IEA Mus musculus 28694 R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 28694 R-RNO-209891 https://reactome.org/PathwayBrowser/#/R-RNO-209891 Dopamine is oxidised to noradrenaline IEA Rattus norvegicus 28694 R-RNO-442368 https://reactome.org/PathwayBrowser/#/R-RNO-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Rattus norvegicus 28694 R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 28694 R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 28694 R-RNO-917933 https://reactome.org/PathwayBrowser/#/R-RNO-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Rattus norvegicus 28694 R-RNO-9709406 https://reactome.org/PathwayBrowser/#/R-RNO-9709406 CO binds to Cytochrome c oxidase IEA Rattus norvegicus 28694 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa 28694 R-SSC-209891 https://reactome.org/PathwayBrowser/#/R-SSC-209891 Dopamine is oxidised to noradrenaline IEA Sus scrofa 28694 R-SSC-442368 https://reactome.org/PathwayBrowser/#/R-SSC-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Sus scrofa 28694 R-SSC-5696131 https://reactome.org/PathwayBrowser/#/R-SSC-5696131 AOC1 deaminates Hist IEA Sus scrofa 28694 R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa 28694 R-SSC-917933 https://reactome.org/PathwayBrowser/#/R-SSC-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Sus scrofa 28694 R-SSC-9709406 https://reactome.org/PathwayBrowser/#/R-SSC-9709406 CO binds to Cytochrome c oxidase IEA Sus scrofa 28694 R-XTR-163214 https://reactome.org/PathwayBrowser/#/R-XTR-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Xenopus tropicalis 28694 R-XTR-209891 https://reactome.org/PathwayBrowser/#/R-XTR-209891 Dopamine is oxidised to noradrenaline IEA Xenopus tropicalis 28694 R-XTR-442368 https://reactome.org/PathwayBrowser/#/R-XTR-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Xenopus tropicalis 28694 R-XTR-5696131 https://reactome.org/PathwayBrowser/#/R-XTR-5696131 AOC1 deaminates Hist IEA Xenopus tropicalis 28694 R-XTR-5696183 https://reactome.org/PathwayBrowser/#/R-XTR-5696183 AOC3 deaminates BZAM IEA Xenopus tropicalis 28694 R-XTR-917933 https://reactome.org/PathwayBrowser/#/R-XTR-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Xenopus tropicalis 28694 R-XTR-9709406 https://reactome.org/PathwayBrowser/#/R-XTR-9709406 CO binds to Cytochrome c oxidase IEA Xenopus tropicalis 28716 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 28716 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 28716 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 28716 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 28716 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 28716 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 28716 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 28716 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 28716 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 28716 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 28716 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 28716 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 28716 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 28716 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 28716 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 28716 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 28716 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 28716 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 28716 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 28716 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 28716 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 28716 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 28716 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 28716 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 28716 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 28716 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 28716 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 28716 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 28716 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 28716 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 28716 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 28716 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 28716 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 28716 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 28716 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 28726 R-BTA-77271 https://reactome.org/PathwayBrowser/#/R-BTA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Bos taurus 28726 R-BTA-77283 https://reactome.org/PathwayBrowser/#/R-BTA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Bos taurus 28726 R-CEL-77271 https://reactome.org/PathwayBrowser/#/R-CEL-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Caenorhabditis elegans 28726 R-CEL-77283 https://reactome.org/PathwayBrowser/#/R-CEL-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 28726 R-CFA-77271 https://reactome.org/PathwayBrowser/#/R-CFA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Canis familiaris 28726 R-CFA-77283 https://reactome.org/PathwayBrowser/#/R-CFA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Canis familiaris 28726 R-DME-77271 https://reactome.org/PathwayBrowser/#/R-DME-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Drosophila melanogaster 28726 R-DME-77283 https://reactome.org/PathwayBrowser/#/R-DME-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Drosophila melanogaster 28726 R-DRE-77271 https://reactome.org/PathwayBrowser/#/R-DRE-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Danio rerio 28726 R-DRE-77283 https://reactome.org/PathwayBrowser/#/R-DRE-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Danio rerio 28726 R-GGA-77271 https://reactome.org/PathwayBrowser/#/R-GGA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Gallus gallus 28726 R-GGA-77283 https://reactome.org/PathwayBrowser/#/R-GGA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Gallus gallus 28726 R-HSA-77271 https://reactome.org/PathwayBrowser/#/R-HSA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA TAS Homo sapiens 28726 R-HSA-77283 https://reactome.org/PathwayBrowser/#/R-HSA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H TAS Homo sapiens 28726 R-MMU-77271 https://reactome.org/PathwayBrowser/#/R-MMU-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Mus musculus 28726 R-MMU-77283 https://reactome.org/PathwayBrowser/#/R-MMU-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Mus musculus 28726 R-RNO-77271 https://reactome.org/PathwayBrowser/#/R-RNO-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Rattus norvegicus 28726 R-RNO-77283 https://reactome.org/PathwayBrowser/#/R-RNO-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Rattus norvegicus 28726 R-SSC-77271 https://reactome.org/PathwayBrowser/#/R-SSC-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Sus scrofa 28726 R-SSC-77283 https://reactome.org/PathwayBrowser/#/R-SSC-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Sus scrofa 28726 R-XTR-77271 https://reactome.org/PathwayBrowser/#/R-XTR-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Xenopus tropicalis 28726 R-XTR-77283 https://reactome.org/PathwayBrowser/#/R-XTR-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Xenopus tropicalis 28728 R-HSA-2161732 https://reactome.org/PathwayBrowser/#/R-HSA-2161732 TXB2 is converted to 11dh-TXB2 by TXDH TAS Homo sapiens 28728 R-HSA-443894 https://reactome.org/PathwayBrowser/#/R-HSA-443894 TXA2 is hydrolysed to TXB2 TAS Homo sapiens 28750 R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 28750 R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 28750 R-BTA-196372 https://reactome.org/PathwayBrowser/#/R-BTA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Bos taurus 28750 R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 28750 R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 28750 R-CFA-196372 https://reactome.org/PathwayBrowser/#/R-CFA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Canis familiaris 28750 R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 28750 R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 28750 R-DRE-196372 https://reactome.org/PathwayBrowser/#/R-DRE-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Danio rerio 28750 R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 28750 R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 28750 R-GGA-196372 https://reactome.org/PathwayBrowser/#/R-GGA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Gallus gallus 28750 R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 28750 R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 28750 R-HSA-196372 https://reactome.org/PathwayBrowser/#/R-HSA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol TAS Homo sapiens 28750 R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 28750 R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 28750 R-MMU-196372 https://reactome.org/PathwayBrowser/#/R-MMU-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Mus musculus 28750 R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 28750 R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 28750 R-RNO-196372 https://reactome.org/PathwayBrowser/#/R-RNO-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Rattus norvegicus 28750 R-SSC-193068 https://reactome.org/PathwayBrowser/#/R-SSC-193068 CYP17A1 17-hydroxylates PREG IEA Sus scrofa 28750 R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 28750 R-SSC-196372 https://reactome.org/PathwayBrowser/#/R-SSC-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Sus scrofa 28750 R-XTR-193068 https://reactome.org/PathwayBrowser/#/R-XTR-193068 CYP17A1 17-hydroxylates PREG IEA Xenopus tropicalis 28750 R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 2877 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2877 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 2877 R-BTA-5696365 https://reactome.org/PathwayBrowser/#/R-BTA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Bos taurus 2877 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2877 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2877 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 2877 R-CFA-5696365 https://reactome.org/PathwayBrowser/#/R-CFA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Canis familiaris 2877 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 2877 R-DME-5696365 https://reactome.org/PathwayBrowser/#/R-DME-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Drosophila melanogaster 2877 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2877 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 2877 R-DRE-5696365 https://reactome.org/PathwayBrowser/#/R-DRE-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Danio rerio 2877 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 2877 R-GGA-5696365 https://reactome.org/PathwayBrowser/#/R-GGA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Gallus gallus 2877 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2877 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 2877 R-HSA-5696365 https://reactome.org/PathwayBrowser/#/R-HSA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe TAS Homo sapiens 2877 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2877 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2877 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 2877 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 2877 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 2877 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2877 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 2877 R-MMU-5696365 https://reactome.org/PathwayBrowser/#/R-MMU-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Mus musculus 2877 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2877 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2877 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 2877 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2877 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 2877 R-RNO-5696365 https://reactome.org/PathwayBrowser/#/R-RNO-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Rattus norvegicus 2877 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 2877 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2877 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 2877 R-SSC-5696365 https://reactome.org/PathwayBrowser/#/R-SSC-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Sus scrofa 2877 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2877 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2877 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 28774 R-BTA-176585 https://reactome.org/PathwayBrowser/#/R-BTA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Bos taurus 28774 R-BTA-209772 https://reactome.org/PathwayBrowser/#/R-BTA-209772 Thyroxine is deiodinated to triiodothyronine IEA Bos taurus 28774 R-BTA-209925 https://reactome.org/PathwayBrowser/#/R-BTA-209925 DIT and MIT combine to form triiodothyronine IEA Bos taurus 28774 R-BTA-350869 https://reactome.org/PathwayBrowser/#/R-BTA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Bos taurus 28774 R-BTA-879575 https://reactome.org/PathwayBrowser/#/R-BTA-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Bos taurus 28774 R-BTA-9631987 https://reactome.org/PathwayBrowser/#/R-BTA-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Bos taurus 28774 R-CEL-176585 https://reactome.org/PathwayBrowser/#/R-CEL-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Caenorhabditis elegans 28774 R-CEL-209925 https://reactome.org/PathwayBrowser/#/R-CEL-209925 DIT and MIT combine to form triiodothyronine IEA Caenorhabditis elegans 28774 R-CEL-879575 https://reactome.org/PathwayBrowser/#/R-CEL-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Caenorhabditis elegans 28774 R-CEL-9631987 https://reactome.org/PathwayBrowser/#/R-CEL-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Caenorhabditis elegans 28774 R-CFA-176585 https://reactome.org/PathwayBrowser/#/R-CFA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Canis familiaris 28774 R-CFA-209772 https://reactome.org/PathwayBrowser/#/R-CFA-209772 Thyroxine is deiodinated to triiodothyronine IEA Canis familiaris 28774 R-CFA-209925 https://reactome.org/PathwayBrowser/#/R-CFA-209925 DIT and MIT combine to form triiodothyronine IEA Canis familiaris 28774 R-CFA-879575 https://reactome.org/PathwayBrowser/#/R-CFA-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Canis familiaris 28774 R-CFA-9631987 https://reactome.org/PathwayBrowser/#/R-CFA-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Canis familiaris 28774 R-DDI-209772 https://reactome.org/PathwayBrowser/#/R-DDI-209772 Thyroxine is deiodinated to triiodothyronine IEA Dictyostelium discoideum 28774 R-DDI-209925 https://reactome.org/PathwayBrowser/#/R-DDI-209925 DIT and MIT combine to form triiodothyronine IEA Dictyostelium discoideum 28774 R-DDI-350869 https://reactome.org/PathwayBrowser/#/R-DDI-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Dictyostelium discoideum 28774 R-DDI-879575 https://reactome.org/PathwayBrowser/#/R-DDI-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Dictyostelium discoideum 28774 R-DME-176585 https://reactome.org/PathwayBrowser/#/R-DME-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Drosophila melanogaster 28774 R-DME-209925 https://reactome.org/PathwayBrowser/#/R-DME-209925 DIT and MIT combine to form triiodothyronine IEA Drosophila melanogaster 28774 R-DME-879575 https://reactome.org/PathwayBrowser/#/R-DME-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Drosophila melanogaster 28774 R-DME-9631987 https://reactome.org/PathwayBrowser/#/R-DME-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Drosophila melanogaster 28774 R-DRE-176585 https://reactome.org/PathwayBrowser/#/R-DRE-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Danio rerio 28774 R-DRE-879575 https://reactome.org/PathwayBrowser/#/R-DRE-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Danio rerio 28774 R-DRE-9631987 https://reactome.org/PathwayBrowser/#/R-DRE-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Danio rerio 28774 R-GGA-176585 https://reactome.org/PathwayBrowser/#/R-GGA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Gallus gallus 28774 R-GGA-209772 https://reactome.org/PathwayBrowser/#/R-GGA-209772 Thyroxine is deiodinated to triiodothyronine IEA Gallus gallus 28774 R-GGA-209925 https://reactome.org/PathwayBrowser/#/R-GGA-209925 DIT and MIT combine to form triiodothyronine IEA Gallus gallus 28774 R-GGA-879575 https://reactome.org/PathwayBrowser/#/R-GGA-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Gallus gallus 28774 R-GGA-9631987 https://reactome.org/PathwayBrowser/#/R-GGA-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Gallus gallus 28774 R-HSA-176585 https://reactome.org/PathwayBrowser/#/R-HSA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP TAS Homo sapiens 28774 R-HSA-209772 https://reactome.org/PathwayBrowser/#/R-HSA-209772 Thyroxine is deiodinated to triiodothyronine TAS Homo sapiens 28774 R-HSA-209925 https://reactome.org/PathwayBrowser/#/R-HSA-209925 DIT and MIT combine to form triiodothyronine TAS Homo sapiens 28774 R-HSA-350869 https://reactome.org/PathwayBrowser/#/R-HSA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) TAS Homo sapiens 28774 R-HSA-879575 https://reactome.org/PathwayBrowser/#/R-HSA-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol TAS Homo sapiens 28774 R-HSA-9631987 https://reactome.org/PathwayBrowser/#/R-HSA-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol TAS Homo sapiens 28774 R-MMU-176585 https://reactome.org/PathwayBrowser/#/R-MMU-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Mus musculus 28774 R-MMU-209772 https://reactome.org/PathwayBrowser/#/R-MMU-209772 Thyroxine is deiodinated to triiodothyronine IEA Mus musculus 28774 R-MMU-209925 https://reactome.org/PathwayBrowser/#/R-MMU-209925 DIT and MIT combine to form triiodothyronine IEA Mus musculus 28774 R-MMU-350869 https://reactome.org/PathwayBrowser/#/R-MMU-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Mus musculus 28774 R-MMU-879575 https://reactome.org/PathwayBrowser/#/R-MMU-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Mus musculus 28774 R-MMU-9631987 https://reactome.org/PathwayBrowser/#/R-MMU-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Mus musculus 28774 R-PFA-879575 https://reactome.org/PathwayBrowser/#/R-PFA-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Plasmodium falciparum 28774 R-RNO-176585 https://reactome.org/PathwayBrowser/#/R-RNO-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Rattus norvegicus 28774 R-RNO-209772 https://reactome.org/PathwayBrowser/#/R-RNO-209772 Thyroxine is deiodinated to triiodothyronine IEA Rattus norvegicus 28774 R-RNO-209925 https://reactome.org/PathwayBrowser/#/R-RNO-209925 DIT and MIT combine to form triiodothyronine IEA Rattus norvegicus 28774 R-RNO-350869 https://reactome.org/PathwayBrowser/#/R-RNO-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Rattus norvegicus 28774 R-RNO-879575 https://reactome.org/PathwayBrowser/#/R-RNO-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Rattus norvegicus 28774 R-RNO-9631987 https://reactome.org/PathwayBrowser/#/R-RNO-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Rattus norvegicus 28774 R-SCE-879575 https://reactome.org/PathwayBrowser/#/R-SCE-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Saccharomyces cerevisiae 28774 R-SSC-176585 https://reactome.org/PathwayBrowser/#/R-SSC-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Sus scrofa 28774 R-SSC-209772 https://reactome.org/PathwayBrowser/#/R-SSC-209772 Thyroxine is deiodinated to triiodothyronine IEA Sus scrofa 28774 R-SSC-209925 https://reactome.org/PathwayBrowser/#/R-SSC-209925 DIT and MIT combine to form triiodothyronine IEA Sus scrofa 28774 R-SSC-350869 https://reactome.org/PathwayBrowser/#/R-SSC-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Sus scrofa 28774 R-SSC-879575 https://reactome.org/PathwayBrowser/#/R-SSC-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Sus scrofa 28774 R-SSC-9631987 https://reactome.org/PathwayBrowser/#/R-SSC-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Sus scrofa 28774 R-XTR-176585 https://reactome.org/PathwayBrowser/#/R-XTR-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Xenopus tropicalis 28774 R-XTR-879575 https://reactome.org/PathwayBrowser/#/R-XTR-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Xenopus tropicalis 28774 R-XTR-9631987 https://reactome.org/PathwayBrowser/#/R-XTR-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Xenopus tropicalis 28787 R-BTA-9620103 https://reactome.org/PathwayBrowser/#/R-BTA-9620103 ALDH2 transforms GTN to NO IEA Bos taurus 28787 R-CEL-9620103 https://reactome.org/PathwayBrowser/#/R-CEL-9620103 ALDH2 transforms GTN to NO IEA Caenorhabditis elegans 28787 R-CFA-9620103 https://reactome.org/PathwayBrowser/#/R-CFA-9620103 ALDH2 transforms GTN to NO IEA Canis familiaris 28787 R-DDI-9620103 https://reactome.org/PathwayBrowser/#/R-DDI-9620103 ALDH2 transforms GTN to NO IEA Dictyostelium discoideum 28787 R-DME-9620103 https://reactome.org/PathwayBrowser/#/R-DME-9620103 ALDH2 transforms GTN to NO IEA Drosophila melanogaster 28787 R-DRE-9620103 https://reactome.org/PathwayBrowser/#/R-DRE-9620103 ALDH2 transforms GTN to NO IEA Danio rerio 28787 R-GGA-9620103 https://reactome.org/PathwayBrowser/#/R-GGA-9620103 ALDH2 transforms GTN to NO IEA Gallus gallus 28787 R-HSA-9620103 https://reactome.org/PathwayBrowser/#/R-HSA-9620103 ALDH2 transforms GTN to NO TAS Homo sapiens 28787 R-MMU-9620103 https://reactome.org/PathwayBrowser/#/R-MMU-9620103 ALDH2 transforms GTN to NO IEA Mus musculus 28787 R-RNO-9620103 https://reactome.org/PathwayBrowser/#/R-RNO-9620103 ALDH2 transforms GTN to NO IEA Rattus norvegicus 28787 R-SCE-9620103 https://reactome.org/PathwayBrowser/#/R-SCE-9620103 ALDH2 transforms GTN to NO IEA Saccharomyces cerevisiae 28787 R-SPO-9620103 https://reactome.org/PathwayBrowser/#/R-SPO-9620103 ALDH2 transforms GTN to NO IEA Schizosaccharomyces pombe 28787 R-SSC-9620103 https://reactome.org/PathwayBrowser/#/R-SSC-9620103 ALDH2 transforms GTN to NO IEA Sus scrofa 28787 R-XTR-9620103 https://reactome.org/PathwayBrowser/#/R-XTR-9620103 ALDH2 transforms GTN to NO IEA Xenopus tropicalis 28794 R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 28794 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 28794 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 28794 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 28794 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 28794 R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 28794 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 28794 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 28794 R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 28794 R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 28794 R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 28794 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 28794 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 28794 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 28794 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 28794 R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 28794 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 28794 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 28794 R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 28794 R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 28794 R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 28794 R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 28794 R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 28794 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 28794 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 28794 R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 28794 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 28794 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 28794 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 28794 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 28794 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 28794 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 28794 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 28794 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 28794 R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 28794 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 28794 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 28794 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 28794 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 28794 R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 28794 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 28794 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 28794 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 28794 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 28794 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 28794 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 28794 R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 28794 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 28794 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 28794 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 28794 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 28794 R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 28794 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 28794 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 28794 R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 28794 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 28794 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 28794 R-RNO-76453 https://reactome.org/PathwayBrowser/#/R-RNO-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Rattus norvegicus 28794 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 28794 R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa 28794 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 28794 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 28794 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 28794 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 28794 R-SSC-76453 https://reactome.org/PathwayBrowser/#/R-SSC-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Sus scrofa 28794 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 28794 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 28794 R-XTR-211881 https://reactome.org/PathwayBrowser/#/R-XTR-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Xenopus tropicalis 28794 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 28794 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 28794 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 28794 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 28794 R-XTR-76453 https://reactome.org/PathwayBrowser/#/R-XTR-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Xenopus tropicalis 28803 R-BTA-964962 https://reactome.org/PathwayBrowser/#/R-BTA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Bos taurus 28803 R-BTA-965019 https://reactome.org/PathwayBrowser/#/R-BTA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Bos taurus 28803 R-CEL-964962 https://reactome.org/PathwayBrowser/#/R-CEL-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Caenorhabditis elegans 28803 R-CEL-965019 https://reactome.org/PathwayBrowser/#/R-CEL-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Caenorhabditis elegans 28803 R-CFA-964962 https://reactome.org/PathwayBrowser/#/R-CFA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Canis familiaris 28803 R-CFA-965019 https://reactome.org/PathwayBrowser/#/R-CFA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Canis familiaris 28803 R-DDI-964962 https://reactome.org/PathwayBrowser/#/R-DDI-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Dictyostelium discoideum 28803 R-DDI-965019 https://reactome.org/PathwayBrowser/#/R-DDI-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Dictyostelium discoideum 28803 R-DME-964962 https://reactome.org/PathwayBrowser/#/R-DME-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Drosophila melanogaster 28803 R-DME-965019 https://reactome.org/PathwayBrowser/#/R-DME-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Drosophila melanogaster 28803 R-DRE-964962 https://reactome.org/PathwayBrowser/#/R-DRE-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Danio rerio 28803 R-GGA-964962 https://reactome.org/PathwayBrowser/#/R-GGA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Gallus gallus 28803 R-GGA-965019 https://reactome.org/PathwayBrowser/#/R-GGA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Gallus gallus 28803 R-HSA-964962 https://reactome.org/PathwayBrowser/#/R-HSA-964962 2xPDKX:2xZn2+ phosphorylates PDX TAS Homo sapiens 28803 R-HSA-965019 https://reactome.org/PathwayBrowser/#/R-HSA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP TAS Homo sapiens 28803 R-MMU-964962 https://reactome.org/PathwayBrowser/#/R-MMU-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Mus musculus 28803 R-MMU-965019 https://reactome.org/PathwayBrowser/#/R-MMU-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Mus musculus 28803 R-PFA-964962 https://reactome.org/PathwayBrowser/#/R-PFA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Plasmodium falciparum 28803 R-RNO-964962 https://reactome.org/PathwayBrowser/#/R-RNO-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Rattus norvegicus 28803 R-RNO-965019 https://reactome.org/PathwayBrowser/#/R-RNO-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Rattus norvegicus 28803 R-SCE-964962 https://reactome.org/PathwayBrowser/#/R-SCE-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Saccharomyces cerevisiae 28803 R-SCE-965019 https://reactome.org/PathwayBrowser/#/R-SCE-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Saccharomyces cerevisiae 28803 R-SPO-964962 https://reactome.org/PathwayBrowser/#/R-SPO-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Schizosaccharomyces pombe 28803 R-SPO-965019 https://reactome.org/PathwayBrowser/#/R-SPO-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Schizosaccharomyces pombe 28803 R-SSC-964962 https://reactome.org/PathwayBrowser/#/R-SSC-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Sus scrofa 28803 R-SSC-965019 https://reactome.org/PathwayBrowser/#/R-SSC-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Sus scrofa 28803 R-XTR-964962 https://reactome.org/PathwayBrowser/#/R-XTR-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Xenopus tropicalis 28803 R-XTR-965019 https://reactome.org/PathwayBrowser/#/R-XTR-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Xenopus tropicalis 28808 R-BTA-5621347 https://reactome.org/PathwayBrowser/#/R-BTA-5621347 PLCG2 translocates from cytosol to plasma membrane IEA Bos taurus 28808 R-BTA-5621354 https://reactome.org/PathwayBrowser/#/R-BTA-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Bos taurus 28808 R-BTA-5621355 https://reactome.org/PathwayBrowser/#/R-BTA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Bos taurus 28808 R-BTA-5621363 https://reactome.org/PathwayBrowser/#/R-BTA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Bos taurus 28808 R-BTA-5621366 https://reactome.org/PathwayBrowser/#/R-BTA-5621366 SYK binds to p-Y65,Y76-FCER1G IEA Bos taurus 28808 R-BTA-5621370 https://reactome.org/PathwayBrowser/#/R-BTA-5621370 SYK autophosphorylates IEA Bos taurus 28808 R-CFA-5621347 https://reactome.org/PathwayBrowser/#/R-CFA-5621347 PLCG2 translocates from cytosol to plasma membrane IEA Canis familiaris 28808 R-CFA-5621354 https://reactome.org/PathwayBrowser/#/R-CFA-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Canis familiaris 28808 R-CFA-5621355 https://reactome.org/PathwayBrowser/#/R-CFA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Canis familiaris 28808 R-CFA-5621363 https://reactome.org/PathwayBrowser/#/R-CFA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Canis familiaris 28808 R-CFA-5621366 https://reactome.org/PathwayBrowser/#/R-CFA-5621366 SYK binds to p-Y65,Y76-FCER1G IEA Canis familiaris 28808 R-CFA-5621370 https://reactome.org/PathwayBrowser/#/R-CFA-5621370 SYK autophosphorylates IEA Canis familiaris 28808 R-DRE-5621354 https://reactome.org/PathwayBrowser/#/R-DRE-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Danio rerio 28808 R-DRE-5621355 https://reactome.org/PathwayBrowser/#/R-DRE-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Danio rerio 28808 R-HSA-5621347 https://reactome.org/PathwayBrowser/#/R-HSA-5621347 PLCG2 translocates from cytosol to plasma membrane TAS Homo sapiens 28808 R-HSA-5621352 https://reactome.org/PathwayBrowser/#/R-HSA-5621352 CLEC6A binds alpha-mannan in fungal cell walls IEA Homo sapiens 28808 R-HSA-5621354 https://reactome.org/PathwayBrowser/#/R-HSA-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate TAS Homo sapiens 28808 R-HSA-5621355 https://reactome.org/PathwayBrowser/#/R-HSA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG TAS Homo sapiens 28808 R-HSA-5621356 https://reactome.org/PathwayBrowser/#/R-HSA-5621356 PLCG1 binds p-6Y-SYK:p-Y65,Y76-FCER1G IEA Homo sapiens 28808 R-HSA-5621363 https://reactome.org/PathwayBrowser/#/R-HSA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 TAS Homo sapiens 28808 R-HSA-5621366 https://reactome.org/PathwayBrowser/#/R-HSA-5621366 SYK binds to p-Y65,Y76-FCER1G TAS Homo sapiens 28808 R-HSA-5621370 https://reactome.org/PathwayBrowser/#/R-HSA-5621370 SYK autophosphorylates TAS Homo sapiens 28808 R-MMU-5621347 https://reactome.org/PathwayBrowser/#/R-MMU-5621347 PLCG2 translocates from cytosol to plasma membrane IEA Mus musculus 28808 R-MMU-5621348 https://reactome.org/PathwayBrowser/#/R-MMU-5621348 Clec6a binds alpha-mannan in fungal cell walls TAS Mus musculus 28808 R-MMU-5621354 https://reactome.org/PathwayBrowser/#/R-MMU-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Mus musculus 28808 R-MMU-5621355 https://reactome.org/PathwayBrowser/#/R-MMU-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Mus musculus 28808 R-MMU-5621363 https://reactome.org/PathwayBrowser/#/R-MMU-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Mus musculus 28808 R-MMU-5621366 https://reactome.org/PathwayBrowser/#/R-MMU-5621366 SYK binds to p-Y65,Y76-FCER1G IEA Mus musculus 28808 R-MMU-5621370 https://reactome.org/PathwayBrowser/#/R-MMU-5621370 SYK autophosphorylates IEA Mus musculus 28808 R-RNO-5621347 https://reactome.org/PathwayBrowser/#/R-RNO-5621347 PLCG2 translocates from cytosol to plasma membrane IEA Rattus norvegicus 28808 R-RNO-5621354 https://reactome.org/PathwayBrowser/#/R-RNO-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Rattus norvegicus 28808 R-RNO-5621355 https://reactome.org/PathwayBrowser/#/R-RNO-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Rattus norvegicus 28808 R-RNO-5621363 https://reactome.org/PathwayBrowser/#/R-RNO-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Rattus norvegicus 28808 R-RNO-5621366 https://reactome.org/PathwayBrowser/#/R-RNO-5621366 SYK binds to p-Y65,Y76-FCER1G IEA Rattus norvegicus 28808 R-RNO-5621370 https://reactome.org/PathwayBrowser/#/R-RNO-5621370 SYK autophosphorylates IEA Rattus norvegicus 28808 R-SSC-5621347 https://reactome.org/PathwayBrowser/#/R-SSC-5621347 PLCG2 translocates from cytosol to plasma membrane IEA Sus scrofa 28808 R-SSC-5621354 https://reactome.org/PathwayBrowser/#/R-SSC-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Sus scrofa 28808 R-SSC-5621355 https://reactome.org/PathwayBrowser/#/R-SSC-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Sus scrofa 28808 R-SSC-5621363 https://reactome.org/PathwayBrowser/#/R-SSC-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Sus scrofa 28808 R-SSC-5621366 https://reactome.org/PathwayBrowser/#/R-SSC-5621366 SYK binds to p-Y65,Y76-FCER1G IEA Sus scrofa 28808 R-SSC-5621370 https://reactome.org/PathwayBrowser/#/R-SSC-5621370 SYK autophosphorylates IEA Sus scrofa 28815 R-BTA-109699 https://reactome.org/PathwayBrowser/#/R-BTA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Bos taurus 28815 R-BTA-1307955 https://reactome.org/PathwayBrowser/#/R-BTA-1307955 FGFR4 binds HS:KLB:FGF19 IEA Bos taurus 28815 R-BTA-1307963 https://reactome.org/PathwayBrowser/#/R-BTA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Bos taurus 28815 R-BTA-190245 https://reactome.org/PathwayBrowser/#/R-BTA-190245 FGFR1b binds to FGF IEA Bos taurus 28815 R-BTA-190256 https://reactome.org/PathwayBrowser/#/R-BTA-190256 FGFR1c binds to FGF IEA Bos taurus 28815 R-BTA-190258 https://reactome.org/PathwayBrowser/#/R-BTA-190258 FGFR2c binds to FGF IEA Bos taurus 28815 R-BTA-190260 https://reactome.org/PathwayBrowser/#/R-BTA-190260 FGFR2b binds to FGF IEA Bos taurus 28815 R-BTA-190261 https://reactome.org/PathwayBrowser/#/R-BTA-190261 FGFR3c binds to FGF IEA Bos taurus 28815 R-BTA-190263 https://reactome.org/PathwayBrowser/#/R-BTA-190263 FGFR3b binds to FGF IEA Bos taurus 28815 R-BTA-190265 https://reactome.org/PathwayBrowser/#/R-BTA-190265 FGFR4 binds to FGF IEA Bos taurus 28815 R-BTA-190268 https://reactome.org/PathwayBrowser/#/R-BTA-190268 FGFR1c binds to Klotho-bound FGF23 IEA Bos taurus 28815 R-BTA-190326 https://reactome.org/PathwayBrowser/#/R-BTA-190326 Autocatalytic phosphorylation of FGFR4 IEA Bos taurus 28815 R-BTA-190385 https://reactome.org/PathwayBrowser/#/R-BTA-190385 Autocatalytic phosphorylation of FGFR3b IEA Bos taurus 28815 R-BTA-190388 https://reactome.org/PathwayBrowser/#/R-BTA-190388 Autocatalytic phosphorylation of FGFR3c IEA Bos taurus 28815 R-BTA-190408 https://reactome.org/PathwayBrowser/#/R-BTA-190408 Autocatalytic phosphorylation of FGFR2b IEA Bos taurus 28815 R-BTA-190413 https://reactome.org/PathwayBrowser/#/R-BTA-190413 Autocatalytic phosphorylation of FGFR2c IEA Bos taurus 28815 R-BTA-190427 https://reactome.org/PathwayBrowser/#/R-BTA-190427 Autocatalytic phosphorylation of FGFR1b IEA Bos taurus 28815 R-BTA-190429 https://reactome.org/PathwayBrowser/#/R-BTA-190429 Autocatalytic phosphorylation of FGFR1c IEA Bos taurus 28815 R-BTA-191062 https://reactome.org/PathwayBrowser/#/R-BTA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Bos taurus 28815 R-BTA-204485 https://reactome.org/PathwayBrowser/#/R-BTA-204485 Basigin binds CyPA IEA Bos taurus 28815 R-BTA-2316434 https://reactome.org/PathwayBrowser/#/R-BTA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 28815 R-BTA-5654147 https://reactome.org/PathwayBrowser/#/R-BTA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Bos taurus 28815 R-BTA-5654148 https://reactome.org/PathwayBrowser/#/R-BTA-5654148 p-4Y-PLCG1 dissociates from activated FGFR3 IEA Bos taurus 28815 R-BTA-5654149 https://reactome.org/PathwayBrowser/#/R-BTA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Bos taurus 28815 R-BTA-5654151 https://reactome.org/PathwayBrowser/#/R-BTA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Bos taurus 28815 R-BTA-5654157 https://reactome.org/PathwayBrowser/#/R-BTA-5654157 p-4Y-PLCG1 dissociates from activated FGFR2 IEA Bos taurus 28815 R-BTA-5654159 https://reactome.org/PathwayBrowser/#/R-BTA-5654159 Activated FGFR2 binds PLCG1 IEA Bos taurus 28815 R-BTA-5654163 https://reactome.org/PathwayBrowser/#/R-BTA-5654163 Activated FGFR4 binds PLCG1 IEA Bos taurus 28815 R-BTA-5654165 https://reactome.org/PathwayBrowser/#/R-BTA-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Bos taurus 28815 R-BTA-5654167 https://reactome.org/PathwayBrowser/#/R-BTA-5654167 Activated FGFR1 binds PLCG1 IEA Bos taurus 28815 R-BTA-5654169 https://reactome.org/PathwayBrowser/#/R-BTA-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Bos taurus 28815 R-BTA-5654222 https://reactome.org/PathwayBrowser/#/R-BTA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Bos taurus 28815 R-BTA-5654224 https://reactome.org/PathwayBrowser/#/R-BTA-5654224 Activated FGFR3 binds PLCG1 IEA Bos taurus 28815 R-BTA-5654392 https://reactome.org/PathwayBrowser/#/R-BTA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-5654397 https://reactome.org/PathwayBrowser/#/R-BTA-5654397 Activated FGFR2 phosphorylates FRS2 IEA Bos taurus 28815 R-BTA-5654399 https://reactome.org/PathwayBrowser/#/R-BTA-5654399 Activated FGFR2 binds FRS2 IEA Bos taurus 28815 R-BTA-5654402 https://reactome.org/PathwayBrowser/#/R-BTA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-5654404 https://reactome.org/PathwayBrowser/#/R-BTA-5654404 Activated FGFR2 binds SHC1 IEA Bos taurus 28815 R-BTA-5654406 https://reactome.org/PathwayBrowser/#/R-BTA-5654406 Activated FGFR2:p-SHC1 binds GRB2:SOS1 IEA Bos taurus 28815 R-BTA-5654407 https://reactome.org/PathwayBrowser/#/R-BTA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Bos taurus 28815 R-BTA-5654408 https://reactome.org/PathwayBrowser/#/R-BTA-5654408 Activated FGFR3 phosphorylates FRS2 IEA Bos taurus 28815 R-BTA-5654409 https://reactome.org/PathwayBrowser/#/R-BTA-5654409 Activated FGFR3 binds FRS2 IEA Bos taurus 28815 R-BTA-5654413 https://reactome.org/PathwayBrowser/#/R-BTA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-5654416 https://reactome.org/PathwayBrowser/#/R-BTA-5654416 Activated FGFR3:pFRS binds GRB2:SOS1 IEA Bos taurus 28815 R-BTA-5654418 https://reactome.org/PathwayBrowser/#/R-BTA-5654418 Activated FGFR4 phosphorylates FRS2 IEA Bos taurus 28815 R-BTA-5654422 https://reactome.org/PathwayBrowser/#/R-BTA-5654422 Activated FGFR4 binds FRS2 IEA Bos taurus 28815 R-BTA-5654423 https://reactome.org/PathwayBrowser/#/R-BTA-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Bos taurus 28815 R-BTA-5654425 https://reactome.org/PathwayBrowser/#/R-BTA-5654425 Activated FGFR4 binds SHC1 IEA Bos taurus 28815 R-BTA-5654426 https://reactome.org/PathwayBrowser/#/R-BTA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-5654428 https://reactome.org/PathwayBrowser/#/R-BTA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Bos taurus 28815 R-BTA-5654511 https://reactome.org/PathwayBrowser/#/R-BTA-5654511 FGFRL1 dimer binds FGFs IEA Bos taurus 28815 R-BTA-5654560 https://reactome.org/PathwayBrowser/#/R-BTA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Bos taurus 28815 R-BTA-5654562 https://reactome.org/PathwayBrowser/#/R-BTA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Bos taurus 28815 R-BTA-5654565 https://reactome.org/PathwayBrowser/#/R-BTA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Bos taurus 28815 R-BTA-5654566 https://reactome.org/PathwayBrowser/#/R-BTA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Bos taurus 28815 R-BTA-5654569 https://reactome.org/PathwayBrowser/#/R-BTA-5654569 Activated FGFR1 binds FRS2 IEA Bos taurus 28815 R-BTA-5654571 https://reactome.org/PathwayBrowser/#/R-BTA-5654571 Activated FGFR1 binds FRS3 IEA Bos taurus 28815 R-BTA-5654573 https://reactome.org/PathwayBrowser/#/R-BTA-5654573 Activated FGFR1 binds SHC1 IEA Bos taurus 28815 R-BTA-5654575 https://reactome.org/PathwayBrowser/#/R-BTA-5654575 Activated FGFR1 phosphorylates FRS2 IEA Bos taurus 28815 R-BTA-5654578 https://reactome.org/PathwayBrowser/#/R-BTA-5654578 Activated FGFR1 phosphorylates FRS3 IEA Bos taurus 28815 R-BTA-5654582 https://reactome.org/PathwayBrowser/#/R-BTA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Bos taurus 28815 R-BTA-5654584 https://reactome.org/PathwayBrowser/#/R-BTA-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Bos taurus 28815 R-BTA-5654586 https://reactome.org/PathwayBrowser/#/R-BTA-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Bos taurus 28815 R-BTA-5654587 https://reactome.org/PathwayBrowser/#/R-BTA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Bos taurus 28815 R-BTA-5654591 https://reactome.org/PathwayBrowser/#/R-BTA-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Bos taurus 28815 R-BTA-5654592 https://reactome.org/PathwayBrowser/#/R-BTA-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Bos taurus 28815 R-BTA-5654594 https://reactome.org/PathwayBrowser/#/R-BTA-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Bos taurus 28815 R-BTA-5654596 https://reactome.org/PathwayBrowser/#/R-BTA-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Bos taurus 28815 R-BTA-5654597 https://reactome.org/PathwayBrowser/#/R-BTA-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Bos taurus 28815 R-BTA-5654600 https://reactome.org/PathwayBrowser/#/R-BTA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-5654603 https://reactome.org/PathwayBrowser/#/R-BTA-5654603 Activated FGFR2 binds FRS3 IEA Bos taurus 28815 R-BTA-5654605 https://reactome.org/PathwayBrowser/#/R-BTA-5654605 Activated FGFR2 phosphorylates FRS3 IEA Bos taurus 28815 R-BTA-5654607 https://reactome.org/PathwayBrowser/#/R-BTA-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Bos taurus 28815 R-BTA-5654608 https://reactome.org/PathwayBrowser/#/R-BTA-5654608 Activated FGFR2:p-FRS bind to PPTN11 IEA Bos taurus 28815 R-BTA-5654612 https://reactome.org/PathwayBrowser/#/R-BTA-5654612 Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Bos taurus 28815 R-BTA-5654614 https://reactome.org/PathwayBrowser/#/R-BTA-5654614 Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Bos taurus 28815 R-BTA-5654615 https://reactome.org/PathwayBrowser/#/R-BTA-5654615 Activated FGFR2:pFRS binds GRB2:SOS1 IEA Bos taurus 28815 R-BTA-5654618 https://reactome.org/PathwayBrowser/#/R-BTA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-5654620 https://reactome.org/PathwayBrowser/#/R-BTA-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Bos taurus 28815 R-BTA-5654622 https://reactome.org/PathwayBrowser/#/R-BTA-5654622 Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Bos taurus 28815 R-BTA-5654623 https://reactome.org/PathwayBrowser/#/R-BTA-5654623 Activated FGFR3 binds FRS3 IEA Bos taurus 28815 R-BTA-5654625 https://reactome.org/PathwayBrowser/#/R-BTA-5654625 Activated FGFR3 binds SHC1 IEA Bos taurus 28815 R-BTA-5654628 https://reactome.org/PathwayBrowser/#/R-BTA-5654628 Activated FGFR3 phosphorylates FRS3 IEA Bos taurus 28815 R-BTA-5654631 https://reactome.org/PathwayBrowser/#/R-BTA-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Bos taurus 28815 R-BTA-5654633 https://reactome.org/PathwayBrowser/#/R-BTA-5654633 Activated FGFR3:p-FRS bind to PPTN11 IEA Bos taurus 28815 R-BTA-5654634 https://reactome.org/PathwayBrowser/#/R-BTA-5654634 Activated FGFR3 phosphorylates SHC1 IEA Bos taurus 28815 R-BTA-5654637 https://reactome.org/PathwayBrowser/#/R-BTA-5654637 Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Bos taurus 28815 R-BTA-5654640 https://reactome.org/PathwayBrowser/#/R-BTA-5654640 Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Bos taurus 28815 R-BTA-5654641 https://reactome.org/PathwayBrowser/#/R-BTA-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Bos taurus 28815 R-BTA-5654643 https://reactome.org/PathwayBrowser/#/R-BTA-5654643 Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Bos taurus 28815 R-BTA-5654646 https://reactome.org/PathwayBrowser/#/R-BTA-5654646 Activated FGFR3:p-SHC1 binds GRB2:SOS1 IEA Bos taurus 28815 R-BTA-5654647 https://reactome.org/PathwayBrowser/#/R-BTA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-5654651 https://reactome.org/PathwayBrowser/#/R-BTA-5654651 Activated FGFR4 binds FRS3 IEA Bos taurus 28815 R-BTA-5654653 https://reactome.org/PathwayBrowser/#/R-BTA-5654653 Activated FGFR4 phosphorylates FRS3 IEA Bos taurus 28815 R-BTA-5654655 https://reactome.org/PathwayBrowser/#/R-BTA-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Bos taurus 28815 R-BTA-5654658 https://reactome.org/PathwayBrowser/#/R-BTA-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Bos taurus 28815 R-BTA-5654659 https://reactome.org/PathwayBrowser/#/R-BTA-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Bos taurus 28815 R-BTA-5654662 https://reactome.org/PathwayBrowser/#/R-BTA-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Bos taurus 28815 R-BTA-5654663 https://reactome.org/PathwayBrowser/#/R-BTA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-5654664 https://reactome.org/PathwayBrowser/#/R-BTA-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Bos taurus 28815 R-BTA-5654667 https://reactome.org/PathwayBrowser/#/R-BTA-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Bos taurus 28815 R-BTA-5654669 https://reactome.org/PathwayBrowser/#/R-BTA-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Bos taurus 28815 R-BTA-5654672 https://reactome.org/PathwayBrowser/#/R-BTA-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Bos taurus 28815 R-BTA-5654673 https://reactome.org/PathwayBrowser/#/R-BTA-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Bos taurus 28815 R-BTA-5654677 https://reactome.org/PathwayBrowser/#/R-BTA-5654677 CBL ubiquitinates FRS2 and FGFR2 IEA Bos taurus 28815 R-BTA-5654679 https://reactome.org/PathwayBrowser/#/R-BTA-5654679 CBL ubiquitinates FRS2 and FGFR3 IEA Bos taurus 28815 R-BTA-5654684 https://reactome.org/PathwayBrowser/#/R-BTA-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Bos taurus 28815 R-BTA-5654690 https://reactome.org/PathwayBrowser/#/R-BTA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 28815 R-BTA-5654692 https://reactome.org/PathwayBrowser/#/R-BTA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 28815 R-BTA-5654697 https://reactome.org/PathwayBrowser/#/R-BTA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 28815 R-BTA-5654701 https://reactome.org/PathwayBrowser/#/R-BTA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 28815 R-BTA-5654705 https://reactome.org/PathwayBrowser/#/R-BTA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 28815 R-BTA-5654709 https://reactome.org/PathwayBrowser/#/R-BTA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 28815 R-BTA-5654714 https://reactome.org/PathwayBrowser/#/R-BTA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 28815 R-BTA-5654717 https://reactome.org/PathwayBrowser/#/R-BTA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 28815 R-BTA-5654729 https://reactome.org/PathwayBrowser/#/R-BTA-5654729 p-CBL:GRB2 binds p-FRS2:activated FGFR2 IEA Bos taurus 28815 R-BTA-5654730 https://reactome.org/PathwayBrowser/#/R-BTA-5654730 p-CBL:GRB2 binds p-FRS2:activated FGFR3 IEA Bos taurus 28815 R-BTA-5654734 https://reactome.org/PathwayBrowser/#/R-BTA-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Bos taurus 28815 R-BTA-5656064 https://reactome.org/PathwayBrowser/#/R-BTA-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Bos taurus 28815 R-BTA-5672965 https://reactome.org/PathwayBrowser/#/R-BTA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-8941613 https://reactome.org/PathwayBrowser/#/R-BTA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-8941618 https://reactome.org/PathwayBrowser/#/R-BTA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-8941623 https://reactome.org/PathwayBrowser/#/R-BTA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 28815 R-BTA-8941628 https://reactome.org/PathwayBrowser/#/R-BTA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 28815 R-CEL-1307955 https://reactome.org/PathwayBrowser/#/R-CEL-1307955 FGFR4 binds HS:KLB:FGF19 IEA Caenorhabditis elegans 28815 R-CEL-1307963 https://reactome.org/PathwayBrowser/#/R-CEL-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Caenorhabditis elegans 28815 R-CEL-190245 https://reactome.org/PathwayBrowser/#/R-CEL-190245 FGFR1b binds to FGF IEA Caenorhabditis elegans 28815 R-CEL-190256 https://reactome.org/PathwayBrowser/#/R-CEL-190256 FGFR1c binds to FGF IEA Caenorhabditis elegans 28815 R-CEL-190258 https://reactome.org/PathwayBrowser/#/R-CEL-190258 FGFR2c binds to FGF IEA Caenorhabditis elegans 28815 R-CEL-190260 https://reactome.org/PathwayBrowser/#/R-CEL-190260 FGFR2b binds to FGF IEA Caenorhabditis elegans 28815 R-CEL-190261 https://reactome.org/PathwayBrowser/#/R-CEL-190261 FGFR3c binds to FGF IEA Caenorhabditis elegans 28815 R-CEL-190263 https://reactome.org/PathwayBrowser/#/R-CEL-190263 FGFR3b binds to FGF IEA Caenorhabditis elegans 28815 R-CEL-190265 https://reactome.org/PathwayBrowser/#/R-CEL-190265 FGFR4 binds to FGF IEA Caenorhabditis elegans 28815 R-CEL-190268 https://reactome.org/PathwayBrowser/#/R-CEL-190268 FGFR1c binds to Klotho-bound FGF23 IEA Caenorhabditis elegans 28815 R-CEL-190326 https://reactome.org/PathwayBrowser/#/R-CEL-190326 Autocatalytic phosphorylation of FGFR4 IEA Caenorhabditis elegans 28815 R-CEL-190385 https://reactome.org/PathwayBrowser/#/R-CEL-190385 Autocatalytic phosphorylation of FGFR3b IEA Caenorhabditis elegans 28815 R-CEL-190388 https://reactome.org/PathwayBrowser/#/R-CEL-190388 Autocatalytic phosphorylation of FGFR3c IEA Caenorhabditis elegans 28815 R-CEL-190408 https://reactome.org/PathwayBrowser/#/R-CEL-190408 Autocatalytic phosphorylation of FGFR2b IEA Caenorhabditis elegans 28815 R-CEL-190413 https://reactome.org/PathwayBrowser/#/R-CEL-190413 Autocatalytic phosphorylation of FGFR2c IEA Caenorhabditis elegans 28815 R-CEL-190427 https://reactome.org/PathwayBrowser/#/R-CEL-190427 Autocatalytic phosphorylation of FGFR1b IEA Caenorhabditis elegans 28815 R-CEL-190429 https://reactome.org/PathwayBrowser/#/R-CEL-190429 Autocatalytic phosphorylation of FGFR1c IEA Caenorhabditis elegans 28815 R-CEL-191062 https://reactome.org/PathwayBrowser/#/R-CEL-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Caenorhabditis elegans 28815 R-CEL-204485 https://reactome.org/PathwayBrowser/#/R-CEL-204485 Basigin binds CyPA IEA Caenorhabditis elegans 28815 R-CEL-2316434 https://reactome.org/PathwayBrowser/#/R-CEL-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 28815 R-CEL-5654149 https://reactome.org/PathwayBrowser/#/R-CEL-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Caenorhabditis elegans 28815 R-CEL-5654151 https://reactome.org/PathwayBrowser/#/R-CEL-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Caenorhabditis elegans 28815 R-CEL-5654392 https://reactome.org/PathwayBrowser/#/R-CEL-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 28815 R-CEL-5654402 https://reactome.org/PathwayBrowser/#/R-CEL-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 28815 R-CEL-5654418 https://reactome.org/PathwayBrowser/#/R-CEL-5654418 Activated FGFR4 phosphorylates FRS2 IEA Caenorhabditis elegans 28815 R-CEL-5654423 https://reactome.org/PathwayBrowser/#/R-CEL-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Caenorhabditis elegans 28815 R-CEL-5654426 https://reactome.org/PathwayBrowser/#/R-CEL-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 28815 R-CEL-5654428 https://reactome.org/PathwayBrowser/#/R-CEL-5654428 Activated FGFR4 phosphorylates SHC1 IEA Caenorhabditis elegans 28815 R-CEL-5654511 https://reactome.org/PathwayBrowser/#/R-CEL-5654511 FGFRL1 dimer binds FGFs IEA Caenorhabditis elegans 28815 R-CEL-5654515 https://reactome.org/PathwayBrowser/#/R-CEL-5654515 KAL1 binds HS IEA Caenorhabditis elegans 28815 R-CEL-5654560 https://reactome.org/PathwayBrowser/#/R-CEL-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Caenorhabditis elegans 28815 R-CEL-5654566 https://reactome.org/PathwayBrowser/#/R-CEL-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Caenorhabditis elegans 28815 R-CEL-5654575 https://reactome.org/PathwayBrowser/#/R-CEL-5654575 Activated FGFR1 phosphorylates FRS2 IEA Caenorhabditis elegans 28815 R-CEL-5654578 https://reactome.org/PathwayBrowser/#/R-CEL-5654578 Activated FGFR1 phosphorylates FRS3 IEA Caenorhabditis elegans 28815 R-CEL-5654582 https://reactome.org/PathwayBrowser/#/R-CEL-5654582 Activated FGFR1 phosphorylates SHC1 IEA Caenorhabditis elegans 28815 R-CEL-5654586 https://reactome.org/PathwayBrowser/#/R-CEL-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Caenorhabditis elegans 28815 R-CEL-5654597 https://reactome.org/PathwayBrowser/#/R-CEL-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Caenorhabditis elegans 28815 R-CEL-5654600 https://reactome.org/PathwayBrowser/#/R-CEL-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 28815 R-CEL-5654647 https://reactome.org/PathwayBrowser/#/R-CEL-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 28815 R-CEL-5654653 https://reactome.org/PathwayBrowser/#/R-CEL-5654653 Activated FGFR4 phosphorylates FRS3 IEA Caenorhabditis elegans 28815 R-CEL-5654663 https://reactome.org/PathwayBrowser/#/R-CEL-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 28815 R-CEL-5654664 https://reactome.org/PathwayBrowser/#/R-CEL-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Caenorhabditis elegans 28815 R-CEL-5654690 https://reactome.org/PathwayBrowser/#/R-CEL-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 28815 R-CEL-5654717 https://reactome.org/PathwayBrowser/#/R-CEL-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 28815 R-CEL-5672965 https://reactome.org/PathwayBrowser/#/R-CEL-5672965 RAS GEFs promote RAS nucleotide exchange IEA Caenorhabditis elegans 28815 R-CFA-109699 https://reactome.org/PathwayBrowser/#/R-CFA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Canis familiaris 28815 R-CFA-1307955 https://reactome.org/PathwayBrowser/#/R-CFA-1307955 FGFR4 binds HS:KLB:FGF19 IEA Canis familiaris 28815 R-CFA-1307963 https://reactome.org/PathwayBrowser/#/R-CFA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Canis familiaris 28815 R-CFA-190245 https://reactome.org/PathwayBrowser/#/R-CFA-190245 FGFR1b binds to FGF IEA Canis familiaris 28815 R-CFA-190256 https://reactome.org/PathwayBrowser/#/R-CFA-190256 FGFR1c binds to FGF IEA Canis familiaris 28815 R-CFA-190258 https://reactome.org/PathwayBrowser/#/R-CFA-190258 FGFR2c binds to FGF IEA Canis familiaris 28815 R-CFA-190260 https://reactome.org/PathwayBrowser/#/R-CFA-190260 FGFR2b binds to FGF IEA Canis familiaris 28815 R-CFA-190261 https://reactome.org/PathwayBrowser/#/R-CFA-190261 FGFR3c binds to FGF IEA Canis familiaris 28815 R-CFA-190263 https://reactome.org/PathwayBrowser/#/R-CFA-190263 FGFR3b binds to FGF IEA Canis familiaris 28815 R-CFA-190265 https://reactome.org/PathwayBrowser/#/R-CFA-190265 FGFR4 binds to FGF IEA Canis familiaris 28815 R-CFA-190268 https://reactome.org/PathwayBrowser/#/R-CFA-190268 FGFR1c binds to Klotho-bound FGF23 IEA Canis familiaris 28815 R-CFA-190326 https://reactome.org/PathwayBrowser/#/R-CFA-190326 Autocatalytic phosphorylation of FGFR4 IEA Canis familiaris 28815 R-CFA-190385 https://reactome.org/PathwayBrowser/#/R-CFA-190385 Autocatalytic phosphorylation of FGFR3b IEA Canis familiaris 28815 R-CFA-190388 https://reactome.org/PathwayBrowser/#/R-CFA-190388 Autocatalytic phosphorylation of FGFR3c IEA Canis familiaris 28815 R-CFA-190408 https://reactome.org/PathwayBrowser/#/R-CFA-190408 Autocatalytic phosphorylation of FGFR2b IEA Canis familiaris 28815 R-CFA-190413 https://reactome.org/PathwayBrowser/#/R-CFA-190413 Autocatalytic phosphorylation of FGFR2c IEA Canis familiaris 28815 R-CFA-190427 https://reactome.org/PathwayBrowser/#/R-CFA-190427 Autocatalytic phosphorylation of FGFR1b IEA Canis familiaris 28815 R-CFA-190429 https://reactome.org/PathwayBrowser/#/R-CFA-190429 Autocatalytic phosphorylation of FGFR1c IEA Canis familiaris 28815 R-CFA-191062 https://reactome.org/PathwayBrowser/#/R-CFA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Canis familiaris 28815 R-CFA-204485 https://reactome.org/PathwayBrowser/#/R-CFA-204485 Basigin binds CyPA IEA Canis familiaris 28815 R-CFA-2316434 https://reactome.org/PathwayBrowser/#/R-CFA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 28815 R-CFA-5654147 https://reactome.org/PathwayBrowser/#/R-CFA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Canis familiaris 28815 R-CFA-5654148 https://reactome.org/PathwayBrowser/#/R-CFA-5654148 p-4Y-PLCG1 dissociates from activated FGFR3 IEA Canis familiaris 28815 R-CFA-5654149 https://reactome.org/PathwayBrowser/#/R-CFA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Canis familiaris 28815 R-CFA-5654151 https://reactome.org/PathwayBrowser/#/R-CFA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Canis familiaris 28815 R-CFA-5654157 https://reactome.org/PathwayBrowser/#/R-CFA-5654157 p-4Y-PLCG1 dissociates from activated FGFR2 IEA Canis familiaris 28815 R-CFA-5654159 https://reactome.org/PathwayBrowser/#/R-CFA-5654159 Activated FGFR2 binds PLCG1 IEA Canis familiaris 28815 R-CFA-5654163 https://reactome.org/PathwayBrowser/#/R-CFA-5654163 Activated FGFR4 binds PLCG1 IEA Canis familiaris 28815 R-CFA-5654165 https://reactome.org/PathwayBrowser/#/R-CFA-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Canis familiaris 28815 R-CFA-5654167 https://reactome.org/PathwayBrowser/#/R-CFA-5654167 Activated FGFR1 binds PLCG1 IEA Canis familiaris 28815 R-CFA-5654169 https://reactome.org/PathwayBrowser/#/R-CFA-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Canis familiaris 28815 R-CFA-5654222 https://reactome.org/PathwayBrowser/#/R-CFA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Canis familiaris 28815 R-CFA-5654224 https://reactome.org/PathwayBrowser/#/R-CFA-5654224 Activated FGFR3 binds PLCG1 IEA Canis familiaris 28815 R-CFA-5654392 https://reactome.org/PathwayBrowser/#/R-CFA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-5654397 https://reactome.org/PathwayBrowser/#/R-CFA-5654397 Activated FGFR2 phosphorylates FRS2 IEA Canis familiaris 28815 R-CFA-5654399 https://reactome.org/PathwayBrowser/#/R-CFA-5654399 Activated FGFR2 binds FRS2 IEA Canis familiaris 28815 R-CFA-5654402 https://reactome.org/PathwayBrowser/#/R-CFA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-5654404 https://reactome.org/PathwayBrowser/#/R-CFA-5654404 Activated FGFR2 binds SHC1 IEA Canis familiaris 28815 R-CFA-5654406 https://reactome.org/PathwayBrowser/#/R-CFA-5654406 Activated FGFR2:p-SHC1 binds GRB2:SOS1 IEA Canis familiaris 28815 R-CFA-5654407 https://reactome.org/PathwayBrowser/#/R-CFA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Canis familiaris 28815 R-CFA-5654408 https://reactome.org/PathwayBrowser/#/R-CFA-5654408 Activated FGFR3 phosphorylates FRS2 IEA Canis familiaris 28815 R-CFA-5654409 https://reactome.org/PathwayBrowser/#/R-CFA-5654409 Activated FGFR3 binds FRS2 IEA Canis familiaris 28815 R-CFA-5654413 https://reactome.org/PathwayBrowser/#/R-CFA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-5654416 https://reactome.org/PathwayBrowser/#/R-CFA-5654416 Activated FGFR3:pFRS binds GRB2:SOS1 IEA Canis familiaris 28815 R-CFA-5654418 https://reactome.org/PathwayBrowser/#/R-CFA-5654418 Activated FGFR4 phosphorylates FRS2 IEA Canis familiaris 28815 R-CFA-5654422 https://reactome.org/PathwayBrowser/#/R-CFA-5654422 Activated FGFR4 binds FRS2 IEA Canis familiaris 28815 R-CFA-5654423 https://reactome.org/PathwayBrowser/#/R-CFA-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Canis familiaris 28815 R-CFA-5654425 https://reactome.org/PathwayBrowser/#/R-CFA-5654425 Activated FGFR4 binds SHC1 IEA Canis familiaris 28815 R-CFA-5654426 https://reactome.org/PathwayBrowser/#/R-CFA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-5654428 https://reactome.org/PathwayBrowser/#/R-CFA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Canis familiaris 28815 R-CFA-5654511 https://reactome.org/PathwayBrowser/#/R-CFA-5654511 FGFRL1 dimer binds FGFs IEA Canis familiaris 28815 R-CFA-5654515 https://reactome.org/PathwayBrowser/#/R-CFA-5654515 KAL1 binds HS IEA Canis familiaris 28815 R-CFA-5654560 https://reactome.org/PathwayBrowser/#/R-CFA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Canis familiaris 28815 R-CFA-5654562 https://reactome.org/PathwayBrowser/#/R-CFA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Canis familiaris 28815 R-CFA-5654565 https://reactome.org/PathwayBrowser/#/R-CFA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Canis familiaris 28815 R-CFA-5654566 https://reactome.org/PathwayBrowser/#/R-CFA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Canis familiaris 28815 R-CFA-5654569 https://reactome.org/PathwayBrowser/#/R-CFA-5654569 Activated FGFR1 binds FRS2 IEA Canis familiaris 28815 R-CFA-5654571 https://reactome.org/PathwayBrowser/#/R-CFA-5654571 Activated FGFR1 binds FRS3 IEA Canis familiaris 28815 R-CFA-5654573 https://reactome.org/PathwayBrowser/#/R-CFA-5654573 Activated FGFR1 binds SHC1 IEA Canis familiaris 28815 R-CFA-5654575 https://reactome.org/PathwayBrowser/#/R-CFA-5654575 Activated FGFR1 phosphorylates FRS2 IEA Canis familiaris 28815 R-CFA-5654578 https://reactome.org/PathwayBrowser/#/R-CFA-5654578 Activated FGFR1 phosphorylates FRS3 IEA Canis familiaris 28815 R-CFA-5654582 https://reactome.org/PathwayBrowser/#/R-CFA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Canis familiaris 28815 R-CFA-5654584 https://reactome.org/PathwayBrowser/#/R-CFA-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Canis familiaris 28815 R-CFA-5654586 https://reactome.org/PathwayBrowser/#/R-CFA-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Canis familiaris 28815 R-CFA-5654587 https://reactome.org/PathwayBrowser/#/R-CFA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Canis familiaris 28815 R-CFA-5654591 https://reactome.org/PathwayBrowser/#/R-CFA-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Canis familiaris 28815 R-CFA-5654592 https://reactome.org/PathwayBrowser/#/R-CFA-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Canis familiaris 28815 R-CFA-5654594 https://reactome.org/PathwayBrowser/#/R-CFA-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Canis familiaris 28815 R-CFA-5654596 https://reactome.org/PathwayBrowser/#/R-CFA-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Canis familiaris 28815 R-CFA-5654597 https://reactome.org/PathwayBrowser/#/R-CFA-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Canis familiaris 28815 R-CFA-5654600 https://reactome.org/PathwayBrowser/#/R-CFA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-5654603 https://reactome.org/PathwayBrowser/#/R-CFA-5654603 Activated FGFR2 binds FRS3 IEA Canis familiaris 28815 R-CFA-5654605 https://reactome.org/PathwayBrowser/#/R-CFA-5654605 Activated FGFR2 phosphorylates FRS3 IEA Canis familiaris 28815 R-CFA-5654607 https://reactome.org/PathwayBrowser/#/R-CFA-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Canis familiaris 28815 R-CFA-5654608 https://reactome.org/PathwayBrowser/#/R-CFA-5654608 Activated FGFR2:p-FRS bind to PPTN11 IEA Canis familiaris 28815 R-CFA-5654612 https://reactome.org/PathwayBrowser/#/R-CFA-5654612 Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Canis familiaris 28815 R-CFA-5654614 https://reactome.org/PathwayBrowser/#/R-CFA-5654614 Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Canis familiaris 28815 R-CFA-5654615 https://reactome.org/PathwayBrowser/#/R-CFA-5654615 Activated FGFR2:pFRS binds GRB2:SOS1 IEA Canis familiaris 28815 R-CFA-5654618 https://reactome.org/PathwayBrowser/#/R-CFA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-5654620 https://reactome.org/PathwayBrowser/#/R-CFA-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Canis familiaris 28815 R-CFA-5654622 https://reactome.org/PathwayBrowser/#/R-CFA-5654622 Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Canis familiaris 28815 R-CFA-5654623 https://reactome.org/PathwayBrowser/#/R-CFA-5654623 Activated FGFR3 binds FRS3 IEA Canis familiaris 28815 R-CFA-5654625 https://reactome.org/PathwayBrowser/#/R-CFA-5654625 Activated FGFR3 binds SHC1 IEA Canis familiaris 28815 R-CFA-5654628 https://reactome.org/PathwayBrowser/#/R-CFA-5654628 Activated FGFR3 phosphorylates FRS3 IEA Canis familiaris 28815 R-CFA-5654631 https://reactome.org/PathwayBrowser/#/R-CFA-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Canis familiaris 28815 R-CFA-5654633 https://reactome.org/PathwayBrowser/#/R-CFA-5654633 Activated FGFR3:p-FRS bind to PPTN11 IEA Canis familiaris 28815 R-CFA-5654634 https://reactome.org/PathwayBrowser/#/R-CFA-5654634 Activated FGFR3 phosphorylates SHC1 IEA Canis familiaris 28815 R-CFA-5654637 https://reactome.org/PathwayBrowser/#/R-CFA-5654637 Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Canis familiaris 28815 R-CFA-5654640 https://reactome.org/PathwayBrowser/#/R-CFA-5654640 Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Canis familiaris 28815 R-CFA-5654641 https://reactome.org/PathwayBrowser/#/R-CFA-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Canis familiaris 28815 R-CFA-5654643 https://reactome.org/PathwayBrowser/#/R-CFA-5654643 Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Canis familiaris 28815 R-CFA-5654646 https://reactome.org/PathwayBrowser/#/R-CFA-5654646 Activated FGFR3:p-SHC1 binds GRB2:SOS1 IEA Canis familiaris 28815 R-CFA-5654647 https://reactome.org/PathwayBrowser/#/R-CFA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-5654651 https://reactome.org/PathwayBrowser/#/R-CFA-5654651 Activated FGFR4 binds FRS3 IEA Canis familiaris 28815 R-CFA-5654653 https://reactome.org/PathwayBrowser/#/R-CFA-5654653 Activated FGFR4 phosphorylates FRS3 IEA Canis familiaris 28815 R-CFA-5654655 https://reactome.org/PathwayBrowser/#/R-CFA-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Canis familiaris 28815 R-CFA-5654658 https://reactome.org/PathwayBrowser/#/R-CFA-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Canis familiaris 28815 R-CFA-5654659 https://reactome.org/PathwayBrowser/#/R-CFA-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Canis familiaris 28815 R-CFA-5654662 https://reactome.org/PathwayBrowser/#/R-CFA-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Canis familiaris 28815 R-CFA-5654663 https://reactome.org/PathwayBrowser/#/R-CFA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-5654664 https://reactome.org/PathwayBrowser/#/R-CFA-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Canis familiaris 28815 R-CFA-5654667 https://reactome.org/PathwayBrowser/#/R-CFA-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Canis familiaris 28815 R-CFA-5654669 https://reactome.org/PathwayBrowser/#/R-CFA-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Canis familiaris 28815 R-CFA-5654672 https://reactome.org/PathwayBrowser/#/R-CFA-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Canis familiaris 28815 R-CFA-5654673 https://reactome.org/PathwayBrowser/#/R-CFA-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Canis familiaris 28815 R-CFA-5654677 https://reactome.org/PathwayBrowser/#/R-CFA-5654677 CBL ubiquitinates FRS2 and FGFR2 IEA Canis familiaris 28815 R-CFA-5654679 https://reactome.org/PathwayBrowser/#/R-CFA-5654679 CBL ubiquitinates FRS2 and FGFR3 IEA Canis familiaris 28815 R-CFA-5654684 https://reactome.org/PathwayBrowser/#/R-CFA-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Canis familiaris 28815 R-CFA-5654690 https://reactome.org/PathwayBrowser/#/R-CFA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 28815 R-CFA-5654692 https://reactome.org/PathwayBrowser/#/R-CFA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 28815 R-CFA-5654697 https://reactome.org/PathwayBrowser/#/R-CFA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 28815 R-CFA-5654701 https://reactome.org/PathwayBrowser/#/R-CFA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 28815 R-CFA-5654705 https://reactome.org/PathwayBrowser/#/R-CFA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 28815 R-CFA-5654709 https://reactome.org/PathwayBrowser/#/R-CFA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 28815 R-CFA-5654714 https://reactome.org/PathwayBrowser/#/R-CFA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 28815 R-CFA-5654717 https://reactome.org/PathwayBrowser/#/R-CFA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 28815 R-CFA-5654729 https://reactome.org/PathwayBrowser/#/R-CFA-5654729 p-CBL:GRB2 binds p-FRS2:activated FGFR2 IEA Canis familiaris 28815 R-CFA-5654730 https://reactome.org/PathwayBrowser/#/R-CFA-5654730 p-CBL:GRB2 binds p-FRS2:activated FGFR3 IEA Canis familiaris 28815 R-CFA-5654734 https://reactome.org/PathwayBrowser/#/R-CFA-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Canis familiaris 28815 R-CFA-5656064 https://reactome.org/PathwayBrowser/#/R-CFA-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Canis familiaris 28815 R-CFA-5672965 https://reactome.org/PathwayBrowser/#/R-CFA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-8941613 https://reactome.org/PathwayBrowser/#/R-CFA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-8941618 https://reactome.org/PathwayBrowser/#/R-CFA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-8941623 https://reactome.org/PathwayBrowser/#/R-CFA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-CFA-8941628 https://reactome.org/PathwayBrowser/#/R-CFA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 28815 R-DME-109699 https://reactome.org/PathwayBrowser/#/R-DME-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Drosophila melanogaster 28815 R-DME-1307955 https://reactome.org/PathwayBrowser/#/R-DME-1307955 FGFR4 binds HS:KLB:FGF19 IEA Drosophila melanogaster 28815 R-DME-1307963 https://reactome.org/PathwayBrowser/#/R-DME-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Drosophila melanogaster 28815 R-DME-190245 https://reactome.org/PathwayBrowser/#/R-DME-190245 FGFR1b binds to FGF IEA Drosophila melanogaster 28815 R-DME-190256 https://reactome.org/PathwayBrowser/#/R-DME-190256 FGFR1c binds to FGF IEA Drosophila melanogaster 28815 R-DME-190258 https://reactome.org/PathwayBrowser/#/R-DME-190258 FGFR2c binds to FGF IEA Drosophila melanogaster 28815 R-DME-190260 https://reactome.org/PathwayBrowser/#/R-DME-190260 FGFR2b binds to FGF IEA Drosophila melanogaster 28815 R-DME-190261 https://reactome.org/PathwayBrowser/#/R-DME-190261 FGFR3c binds to FGF IEA Drosophila melanogaster 28815 R-DME-190263 https://reactome.org/PathwayBrowser/#/R-DME-190263 FGFR3b binds to FGF IEA Drosophila melanogaster 28815 R-DME-190265 https://reactome.org/PathwayBrowser/#/R-DME-190265 FGFR4 binds to FGF IEA Drosophila melanogaster 28815 R-DME-190268 https://reactome.org/PathwayBrowser/#/R-DME-190268 FGFR1c binds to Klotho-bound FGF23 IEA Drosophila melanogaster 28815 R-DME-190326 https://reactome.org/PathwayBrowser/#/R-DME-190326 Autocatalytic phosphorylation of FGFR4 IEA Drosophila melanogaster 28815 R-DME-190385 https://reactome.org/PathwayBrowser/#/R-DME-190385 Autocatalytic phosphorylation of FGFR3b IEA Drosophila melanogaster 28815 R-DME-190388 https://reactome.org/PathwayBrowser/#/R-DME-190388 Autocatalytic phosphorylation of FGFR3c IEA Drosophila melanogaster 28815 R-DME-190408 https://reactome.org/PathwayBrowser/#/R-DME-190408 Autocatalytic phosphorylation of FGFR2b IEA Drosophila melanogaster 28815 R-DME-190413 https://reactome.org/PathwayBrowser/#/R-DME-190413 Autocatalytic phosphorylation of FGFR2c IEA Drosophila melanogaster 28815 R-DME-190427 https://reactome.org/PathwayBrowser/#/R-DME-190427 Autocatalytic phosphorylation of FGFR1b IEA Drosophila melanogaster 28815 R-DME-190429 https://reactome.org/PathwayBrowser/#/R-DME-190429 Autocatalytic phosphorylation of FGFR1c IEA Drosophila melanogaster 28815 R-DME-191062 https://reactome.org/PathwayBrowser/#/R-DME-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Drosophila melanogaster 28815 R-DME-204485 https://reactome.org/PathwayBrowser/#/R-DME-204485 Basigin binds CyPA IEA Drosophila melanogaster 28815 R-DME-2316434 https://reactome.org/PathwayBrowser/#/R-DME-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 28815 R-DME-5654147 https://reactome.org/PathwayBrowser/#/R-DME-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Drosophila melanogaster 28815 R-DME-5654148 https://reactome.org/PathwayBrowser/#/R-DME-5654148 p-4Y-PLCG1 dissociates from activated FGFR3 IEA Drosophila melanogaster 28815 R-DME-5654149 https://reactome.org/PathwayBrowser/#/R-DME-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Drosophila melanogaster 28815 R-DME-5654151 https://reactome.org/PathwayBrowser/#/R-DME-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Drosophila melanogaster 28815 R-DME-5654157 https://reactome.org/PathwayBrowser/#/R-DME-5654157 p-4Y-PLCG1 dissociates from activated FGFR2 IEA Drosophila melanogaster 28815 R-DME-5654159 https://reactome.org/PathwayBrowser/#/R-DME-5654159 Activated FGFR2 binds PLCG1 IEA Drosophila melanogaster 28815 R-DME-5654163 https://reactome.org/PathwayBrowser/#/R-DME-5654163 Activated FGFR4 binds PLCG1 IEA Drosophila melanogaster 28815 R-DME-5654165 https://reactome.org/PathwayBrowser/#/R-DME-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Drosophila melanogaster 28815 R-DME-5654167 https://reactome.org/PathwayBrowser/#/R-DME-5654167 Activated FGFR1 binds PLCG1 IEA Drosophila melanogaster 28815 R-DME-5654169 https://reactome.org/PathwayBrowser/#/R-DME-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Drosophila melanogaster 28815 R-DME-5654222 https://reactome.org/PathwayBrowser/#/R-DME-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Drosophila melanogaster 28815 R-DME-5654224 https://reactome.org/PathwayBrowser/#/R-DME-5654224 Activated FGFR3 binds PLCG1 IEA Drosophila melanogaster 28815 R-DME-5654392 https://reactome.org/PathwayBrowser/#/R-DME-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-5654397 https://reactome.org/PathwayBrowser/#/R-DME-5654397 Activated FGFR2 phosphorylates FRS2 IEA Drosophila melanogaster 28815 R-DME-5654399 https://reactome.org/PathwayBrowser/#/R-DME-5654399 Activated FGFR2 binds FRS2 IEA Drosophila melanogaster 28815 R-DME-5654402 https://reactome.org/PathwayBrowser/#/R-DME-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-5654404 https://reactome.org/PathwayBrowser/#/R-DME-5654404 Activated FGFR2 binds SHC1 IEA Drosophila melanogaster 28815 R-DME-5654406 https://reactome.org/PathwayBrowser/#/R-DME-5654406 Activated FGFR2:p-SHC1 binds GRB2:SOS1 IEA Drosophila melanogaster 28815 R-DME-5654407 https://reactome.org/PathwayBrowser/#/R-DME-5654407 Activated FGFR2 phosphorylates SHC1 IEA Drosophila melanogaster 28815 R-DME-5654408 https://reactome.org/PathwayBrowser/#/R-DME-5654408 Activated FGFR3 phosphorylates FRS2 IEA Drosophila melanogaster 28815 R-DME-5654409 https://reactome.org/PathwayBrowser/#/R-DME-5654409 Activated FGFR3 binds FRS2 IEA Drosophila melanogaster 28815 R-DME-5654413 https://reactome.org/PathwayBrowser/#/R-DME-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-5654416 https://reactome.org/PathwayBrowser/#/R-DME-5654416 Activated FGFR3:pFRS binds GRB2:SOS1 IEA Drosophila melanogaster 28815 R-DME-5654418 https://reactome.org/PathwayBrowser/#/R-DME-5654418 Activated FGFR4 phosphorylates FRS2 IEA Drosophila melanogaster 28815 R-DME-5654422 https://reactome.org/PathwayBrowser/#/R-DME-5654422 Activated FGFR4 binds FRS2 IEA Drosophila melanogaster 28815 R-DME-5654423 https://reactome.org/PathwayBrowser/#/R-DME-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Drosophila melanogaster 28815 R-DME-5654425 https://reactome.org/PathwayBrowser/#/R-DME-5654425 Activated FGFR4 binds SHC1 IEA Drosophila melanogaster 28815 R-DME-5654426 https://reactome.org/PathwayBrowser/#/R-DME-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-5654428 https://reactome.org/PathwayBrowser/#/R-DME-5654428 Activated FGFR4 phosphorylates SHC1 IEA Drosophila melanogaster 28815 R-DME-5654511 https://reactome.org/PathwayBrowser/#/R-DME-5654511 FGFRL1 dimer binds FGFs IEA Drosophila melanogaster 28815 R-DME-5654515 https://reactome.org/PathwayBrowser/#/R-DME-5654515 KAL1 binds HS IEA Drosophila melanogaster 28815 R-DME-5654560 https://reactome.org/PathwayBrowser/#/R-DME-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Drosophila melanogaster 28815 R-DME-5654562 https://reactome.org/PathwayBrowser/#/R-DME-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Drosophila melanogaster 28815 R-DME-5654565 https://reactome.org/PathwayBrowser/#/R-DME-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Drosophila melanogaster 28815 R-DME-5654566 https://reactome.org/PathwayBrowser/#/R-DME-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Drosophila melanogaster 28815 R-DME-5654569 https://reactome.org/PathwayBrowser/#/R-DME-5654569 Activated FGFR1 binds FRS2 IEA Drosophila melanogaster 28815 R-DME-5654571 https://reactome.org/PathwayBrowser/#/R-DME-5654571 Activated FGFR1 binds FRS3 IEA Drosophila melanogaster 28815 R-DME-5654573 https://reactome.org/PathwayBrowser/#/R-DME-5654573 Activated FGFR1 binds SHC1 IEA Drosophila melanogaster 28815 R-DME-5654575 https://reactome.org/PathwayBrowser/#/R-DME-5654575 Activated FGFR1 phosphorylates FRS2 IEA Drosophila melanogaster 28815 R-DME-5654578 https://reactome.org/PathwayBrowser/#/R-DME-5654578 Activated FGFR1 phosphorylates FRS3 IEA Drosophila melanogaster 28815 R-DME-5654582 https://reactome.org/PathwayBrowser/#/R-DME-5654582 Activated FGFR1 phosphorylates SHC1 IEA Drosophila melanogaster 28815 R-DME-5654586 https://reactome.org/PathwayBrowser/#/R-DME-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Drosophila melanogaster 28815 R-DME-5654587 https://reactome.org/PathwayBrowser/#/R-DME-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Drosophila melanogaster 28815 R-DME-5654592 https://reactome.org/PathwayBrowser/#/R-DME-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Drosophila melanogaster 28815 R-DME-5654594 https://reactome.org/PathwayBrowser/#/R-DME-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Drosophila melanogaster 28815 R-DME-5654597 https://reactome.org/PathwayBrowser/#/R-DME-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Drosophila melanogaster 28815 R-DME-5654600 https://reactome.org/PathwayBrowser/#/R-DME-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-5654603 https://reactome.org/PathwayBrowser/#/R-DME-5654603 Activated FGFR2 binds FRS3 IEA Drosophila melanogaster 28815 R-DME-5654605 https://reactome.org/PathwayBrowser/#/R-DME-5654605 Activated FGFR2 phosphorylates FRS3 IEA Drosophila melanogaster 28815 R-DME-5654607 https://reactome.org/PathwayBrowser/#/R-DME-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Drosophila melanogaster 28815 R-DME-5654612 https://reactome.org/PathwayBrowser/#/R-DME-5654612 Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Drosophila melanogaster 28815 R-DME-5654615 https://reactome.org/PathwayBrowser/#/R-DME-5654615 Activated FGFR2:pFRS binds GRB2:SOS1 IEA Drosophila melanogaster 28815 R-DME-5654618 https://reactome.org/PathwayBrowser/#/R-DME-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-5654620 https://reactome.org/PathwayBrowser/#/R-DME-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Drosophila melanogaster 28815 R-DME-5654623 https://reactome.org/PathwayBrowser/#/R-DME-5654623 Activated FGFR3 binds FRS3 IEA Drosophila melanogaster 28815 R-DME-5654625 https://reactome.org/PathwayBrowser/#/R-DME-5654625 Activated FGFR3 binds SHC1 IEA Drosophila melanogaster 28815 R-DME-5654628 https://reactome.org/PathwayBrowser/#/R-DME-5654628 Activated FGFR3 phosphorylates FRS3 IEA Drosophila melanogaster 28815 R-DME-5654631 https://reactome.org/PathwayBrowser/#/R-DME-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Drosophila melanogaster 28815 R-DME-5654634 https://reactome.org/PathwayBrowser/#/R-DME-5654634 Activated FGFR3 phosphorylates SHC1 IEA Drosophila melanogaster 28815 R-DME-5654637 https://reactome.org/PathwayBrowser/#/R-DME-5654637 Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Drosophila melanogaster 28815 R-DME-5654641 https://reactome.org/PathwayBrowser/#/R-DME-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Drosophila melanogaster 28815 R-DME-5654646 https://reactome.org/PathwayBrowser/#/R-DME-5654646 Activated FGFR3:p-SHC1 binds GRB2:SOS1 IEA Drosophila melanogaster 28815 R-DME-5654647 https://reactome.org/PathwayBrowser/#/R-DME-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-5654651 https://reactome.org/PathwayBrowser/#/R-DME-5654651 Activated FGFR4 binds FRS3 IEA Drosophila melanogaster 28815 R-DME-5654653 https://reactome.org/PathwayBrowser/#/R-DME-5654653 Activated FGFR4 phosphorylates FRS3 IEA Drosophila melanogaster 28815 R-DME-5654655 https://reactome.org/PathwayBrowser/#/R-DME-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Drosophila melanogaster 28815 R-DME-5654659 https://reactome.org/PathwayBrowser/#/R-DME-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Drosophila melanogaster 28815 R-DME-5654663 https://reactome.org/PathwayBrowser/#/R-DME-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-5654664 https://reactome.org/PathwayBrowser/#/R-DME-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Drosophila melanogaster 28815 R-DME-5654667 https://reactome.org/PathwayBrowser/#/R-DME-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Drosophila melanogaster 28815 R-DME-5654672 https://reactome.org/PathwayBrowser/#/R-DME-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Drosophila melanogaster 28815 R-DME-5654673 https://reactome.org/PathwayBrowser/#/R-DME-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Drosophila melanogaster 28815 R-DME-5654677 https://reactome.org/PathwayBrowser/#/R-DME-5654677 CBL ubiquitinates FRS2 and FGFR2 IEA Drosophila melanogaster 28815 R-DME-5654679 https://reactome.org/PathwayBrowser/#/R-DME-5654679 CBL ubiquitinates FRS2 and FGFR3 IEA Drosophila melanogaster 28815 R-DME-5654684 https://reactome.org/PathwayBrowser/#/R-DME-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Drosophila melanogaster 28815 R-DME-5654690 https://reactome.org/PathwayBrowser/#/R-DME-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 28815 R-DME-5654692 https://reactome.org/PathwayBrowser/#/R-DME-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 28815 R-DME-5654697 https://reactome.org/PathwayBrowser/#/R-DME-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 28815 R-DME-5654701 https://reactome.org/PathwayBrowser/#/R-DME-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 28815 R-DME-5654705 https://reactome.org/PathwayBrowser/#/R-DME-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 28815 R-DME-5654709 https://reactome.org/PathwayBrowser/#/R-DME-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 28815 R-DME-5654714 https://reactome.org/PathwayBrowser/#/R-DME-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 28815 R-DME-5654717 https://reactome.org/PathwayBrowser/#/R-DME-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 28815 R-DME-5654729 https://reactome.org/PathwayBrowser/#/R-DME-5654729 p-CBL:GRB2 binds p-FRS2:activated FGFR2 IEA Drosophila melanogaster 28815 R-DME-5654730 https://reactome.org/PathwayBrowser/#/R-DME-5654730 p-CBL:GRB2 binds p-FRS2:activated FGFR3 IEA Drosophila melanogaster 28815 R-DME-5654734 https://reactome.org/PathwayBrowser/#/R-DME-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Drosophila melanogaster 28815 R-DME-5656064 https://reactome.org/PathwayBrowser/#/R-DME-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Drosophila melanogaster 28815 R-DME-5672965 https://reactome.org/PathwayBrowser/#/R-DME-5672965 RAS GEFs promote RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-8941613 https://reactome.org/PathwayBrowser/#/R-DME-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-8941618 https://reactome.org/PathwayBrowser/#/R-DME-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-8941623 https://reactome.org/PathwayBrowser/#/R-DME-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DME-8941628 https://reactome.org/PathwayBrowser/#/R-DME-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 28815 R-DRE-190245 https://reactome.org/PathwayBrowser/#/R-DRE-190245 FGFR1b binds to FGF IEA Danio rerio 28815 R-DRE-190256 https://reactome.org/PathwayBrowser/#/R-DRE-190256 FGFR1c binds to FGF IEA Danio rerio 28815 R-DRE-190258 https://reactome.org/PathwayBrowser/#/R-DRE-190258 FGFR2c binds to FGF IEA Danio rerio 28815 R-DRE-190260 https://reactome.org/PathwayBrowser/#/R-DRE-190260 FGFR2b binds to FGF IEA Danio rerio 28815 R-DRE-190261 https://reactome.org/PathwayBrowser/#/R-DRE-190261 FGFR3c binds to FGF IEA Danio rerio 28815 R-DRE-190263 https://reactome.org/PathwayBrowser/#/R-DRE-190263 FGFR3b binds to FGF IEA Danio rerio 28815 R-DRE-190265 https://reactome.org/PathwayBrowser/#/R-DRE-190265 FGFR4 binds to FGF IEA Danio rerio 28815 R-DRE-190268 https://reactome.org/PathwayBrowser/#/R-DRE-190268 FGFR1c binds to Klotho-bound FGF23 IEA Danio rerio 28815 R-DRE-190326 https://reactome.org/PathwayBrowser/#/R-DRE-190326 Autocatalytic phosphorylation of FGFR4 IEA Danio rerio 28815 R-DRE-190385 https://reactome.org/PathwayBrowser/#/R-DRE-190385 Autocatalytic phosphorylation of FGFR3b IEA Danio rerio 28815 R-DRE-190388 https://reactome.org/PathwayBrowser/#/R-DRE-190388 Autocatalytic phosphorylation of FGFR3c IEA Danio rerio 28815 R-DRE-190408 https://reactome.org/PathwayBrowser/#/R-DRE-190408 Autocatalytic phosphorylation of FGFR2b IEA Danio rerio 28815 R-DRE-190413 https://reactome.org/PathwayBrowser/#/R-DRE-190413 Autocatalytic phosphorylation of FGFR2c IEA Danio rerio 28815 R-DRE-190427 https://reactome.org/PathwayBrowser/#/R-DRE-190427 Autocatalytic phosphorylation of FGFR1b IEA Danio rerio 28815 R-DRE-190429 https://reactome.org/PathwayBrowser/#/R-DRE-190429 Autocatalytic phosphorylation of FGFR1c IEA Danio rerio 28815 R-DRE-191062 https://reactome.org/PathwayBrowser/#/R-DRE-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Danio rerio 28815 R-DRE-2316434 https://reactome.org/PathwayBrowser/#/R-DRE-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 28815 R-DRE-5654147 https://reactome.org/PathwayBrowser/#/R-DRE-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Danio rerio 28815 R-DRE-5654148 https://reactome.org/PathwayBrowser/#/R-DRE-5654148 p-4Y-PLCG1 dissociates from activated FGFR3 IEA Danio rerio 28815 R-DRE-5654149 https://reactome.org/PathwayBrowser/#/R-DRE-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Danio rerio 28815 R-DRE-5654151 https://reactome.org/PathwayBrowser/#/R-DRE-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Danio rerio 28815 R-DRE-5654157 https://reactome.org/PathwayBrowser/#/R-DRE-5654157 p-4Y-PLCG1 dissociates from activated FGFR2 IEA Danio rerio 28815 R-DRE-5654159 https://reactome.org/PathwayBrowser/#/R-DRE-5654159 Activated FGFR2 binds PLCG1 IEA Danio rerio 28815 R-DRE-5654163 https://reactome.org/PathwayBrowser/#/R-DRE-5654163 Activated FGFR4 binds PLCG1 IEA Danio rerio 28815 R-DRE-5654165 https://reactome.org/PathwayBrowser/#/R-DRE-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Danio rerio 28815 R-DRE-5654167 https://reactome.org/PathwayBrowser/#/R-DRE-5654167 Activated FGFR1 binds PLCG1 IEA Danio rerio 28815 R-DRE-5654169 https://reactome.org/PathwayBrowser/#/R-DRE-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Danio rerio 28815 R-DRE-5654222 https://reactome.org/PathwayBrowser/#/R-DRE-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Danio rerio 28815 R-DRE-5654224 https://reactome.org/PathwayBrowser/#/R-DRE-5654224 Activated FGFR3 binds PLCG1 IEA Danio rerio 28815 R-DRE-5654392 https://reactome.org/PathwayBrowser/#/R-DRE-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 28815 R-DRE-5654402 https://reactome.org/PathwayBrowser/#/R-DRE-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 28815 R-DRE-5654413 https://reactome.org/PathwayBrowser/#/R-DRE-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 28815 R-DRE-5654416 https://reactome.org/PathwayBrowser/#/R-DRE-5654416 Activated FGFR3:pFRS binds GRB2:SOS1 IEA Danio rerio 28815 R-DRE-5654511 https://reactome.org/PathwayBrowser/#/R-DRE-5654511 FGFRL1 dimer binds FGFs IEA Danio rerio 28815 R-DRE-5654515 https://reactome.org/PathwayBrowser/#/R-DRE-5654515 KAL1 binds HS IEA Danio rerio 28815 R-DRE-5654560 https://reactome.org/PathwayBrowser/#/R-DRE-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Danio rerio 28815 R-DRE-5654571 https://reactome.org/PathwayBrowser/#/R-DRE-5654571 Activated FGFR1 binds FRS3 IEA Danio rerio 28815 R-DRE-5654575 https://reactome.org/PathwayBrowser/#/R-DRE-5654575 Activated FGFR1 phosphorylates FRS2 IEA Danio rerio 28815 R-DRE-5654578 https://reactome.org/PathwayBrowser/#/R-DRE-5654578 Activated FGFR1 phosphorylates FRS3 IEA Danio rerio 28815 R-DRE-5654582 https://reactome.org/PathwayBrowser/#/R-DRE-5654582 Activated FGFR1 phosphorylates SHC1 IEA Danio rerio 28815 R-DRE-5654586 https://reactome.org/PathwayBrowser/#/R-DRE-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Danio rerio 28815 R-DRE-5654587 https://reactome.org/PathwayBrowser/#/R-DRE-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Danio rerio 28815 R-DRE-5654597 https://reactome.org/PathwayBrowser/#/R-DRE-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Danio rerio 28815 R-DRE-5654600 https://reactome.org/PathwayBrowser/#/R-DRE-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 28815 R-DRE-5654603 https://reactome.org/PathwayBrowser/#/R-DRE-5654603 Activated FGFR2 binds FRS3 IEA Danio rerio 28815 R-DRE-5654605 https://reactome.org/PathwayBrowser/#/R-DRE-5654605 Activated FGFR2 phosphorylates FRS3 IEA Danio rerio 28815 R-DRE-5654607 https://reactome.org/PathwayBrowser/#/R-DRE-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Danio rerio 28815 R-DRE-5654615 https://reactome.org/PathwayBrowser/#/R-DRE-5654615 Activated FGFR2:pFRS binds GRB2:SOS1 IEA Danio rerio 28815 R-DRE-5654618 https://reactome.org/PathwayBrowser/#/R-DRE-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 28815 R-DRE-5654623 https://reactome.org/PathwayBrowser/#/R-DRE-5654623 Activated FGFR3 binds FRS3 IEA Danio rerio 28815 R-DRE-5654628 https://reactome.org/PathwayBrowser/#/R-DRE-5654628 Activated FGFR3 phosphorylates FRS3 IEA Danio rerio 28815 R-DRE-5654631 https://reactome.org/PathwayBrowser/#/R-DRE-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Danio rerio 28815 R-DRE-5654647 https://reactome.org/PathwayBrowser/#/R-DRE-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 28815 R-DRE-5654651 https://reactome.org/PathwayBrowser/#/R-DRE-5654651 Activated FGFR4 binds FRS3 IEA Danio rerio 28815 R-DRE-5654653 https://reactome.org/PathwayBrowser/#/R-DRE-5654653 Activated FGFR4 phosphorylates FRS3 IEA Danio rerio 28815 R-DRE-5654663 https://reactome.org/PathwayBrowser/#/R-DRE-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 28815 R-DRE-5654664 https://reactome.org/PathwayBrowser/#/R-DRE-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Danio rerio 28815 R-DRE-5654690 https://reactome.org/PathwayBrowser/#/R-DRE-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 28815 R-DRE-5656064 https://reactome.org/PathwayBrowser/#/R-DRE-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Danio rerio 28815 R-DRE-5672965 https://reactome.org/PathwayBrowser/#/R-DRE-5672965 RAS GEFs promote RAS nucleotide exchange IEA Danio rerio 28815 R-DRE-8941618 https://reactome.org/PathwayBrowser/#/R-DRE-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Danio rerio 28815 R-DRE-8941623 https://reactome.org/PathwayBrowser/#/R-DRE-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Danio rerio 28815 R-DRE-8941628 https://reactome.org/PathwayBrowser/#/R-DRE-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Danio rerio 28815 R-GGA-109699 https://reactome.org/PathwayBrowser/#/R-GGA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Gallus gallus 28815 R-GGA-1307955 https://reactome.org/PathwayBrowser/#/R-GGA-1307955 FGFR4 binds HS:KLB:FGF19 IEA Gallus gallus 28815 R-GGA-1307963 https://reactome.org/PathwayBrowser/#/R-GGA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Gallus gallus 28815 R-GGA-190245 https://reactome.org/PathwayBrowser/#/R-GGA-190245 FGFR1b binds to FGF IEA Gallus gallus 28815 R-GGA-190256 https://reactome.org/PathwayBrowser/#/R-GGA-190256 FGFR1c binds to FGF IEA Gallus gallus 28815 R-GGA-190258 https://reactome.org/PathwayBrowser/#/R-GGA-190258 FGFR2c binds to FGF IEA Gallus gallus 28815 R-GGA-190260 https://reactome.org/PathwayBrowser/#/R-GGA-190260 FGFR2b binds to FGF IEA Gallus gallus 28815 R-GGA-190261 https://reactome.org/PathwayBrowser/#/R-GGA-190261 FGFR3c binds to FGF IEA Gallus gallus 28815 R-GGA-190263 https://reactome.org/PathwayBrowser/#/R-GGA-190263 FGFR3b binds to FGF IEA Gallus gallus 28815 R-GGA-190265 https://reactome.org/PathwayBrowser/#/R-GGA-190265 FGFR4 binds to FGF IEA Gallus gallus 28815 R-GGA-190268 https://reactome.org/PathwayBrowser/#/R-GGA-190268 FGFR1c binds to Klotho-bound FGF23 IEA Gallus gallus 28815 R-GGA-190326 https://reactome.org/PathwayBrowser/#/R-GGA-190326 Autocatalytic phosphorylation of FGFR4 IEA Gallus gallus 28815 R-GGA-190385 https://reactome.org/PathwayBrowser/#/R-GGA-190385 Autocatalytic phosphorylation of FGFR3b IEA Gallus gallus 28815 R-GGA-190388 https://reactome.org/PathwayBrowser/#/R-GGA-190388 Autocatalytic phosphorylation of FGFR3c IEA Gallus gallus 28815 R-GGA-190408 https://reactome.org/PathwayBrowser/#/R-GGA-190408 Autocatalytic phosphorylation of FGFR2b IEA Gallus gallus 28815 R-GGA-190413 https://reactome.org/PathwayBrowser/#/R-GGA-190413 Autocatalytic phosphorylation of FGFR2c IEA Gallus gallus 28815 R-GGA-190427 https://reactome.org/PathwayBrowser/#/R-GGA-190427 Autocatalytic phosphorylation of FGFR1b IEA Gallus gallus 28815 R-GGA-190429 https://reactome.org/PathwayBrowser/#/R-GGA-190429 Autocatalytic phosphorylation of FGFR1c IEA Gallus gallus 28815 R-GGA-191062 https://reactome.org/PathwayBrowser/#/R-GGA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Gallus gallus 28815 R-GGA-204485 https://reactome.org/PathwayBrowser/#/R-GGA-204485 Basigin binds CyPA IEA Gallus gallus 28815 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 28815 R-GGA-5654147 https://reactome.org/PathwayBrowser/#/R-GGA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Gallus gallus 28815 R-GGA-5654148 https://reactome.org/PathwayBrowser/#/R-GGA-5654148 p-4Y-PLCG1 dissociates from activated FGFR3 IEA Gallus gallus 28815 R-GGA-5654149 https://reactome.org/PathwayBrowser/#/R-GGA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Gallus gallus 28815 R-GGA-5654151 https://reactome.org/PathwayBrowser/#/R-GGA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Gallus gallus 28815 R-GGA-5654157 https://reactome.org/PathwayBrowser/#/R-GGA-5654157 p-4Y-PLCG1 dissociates from activated FGFR2 IEA Gallus gallus 28815 R-GGA-5654159 https://reactome.org/PathwayBrowser/#/R-GGA-5654159 Activated FGFR2 binds PLCG1 IEA Gallus gallus 28815 R-GGA-5654163 https://reactome.org/PathwayBrowser/#/R-GGA-5654163 Activated FGFR4 binds PLCG1 IEA Gallus gallus 28815 R-GGA-5654165 https://reactome.org/PathwayBrowser/#/R-GGA-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Gallus gallus 28815 R-GGA-5654167 https://reactome.org/PathwayBrowser/#/R-GGA-5654167 Activated FGFR1 binds PLCG1 IEA Gallus gallus 28815 R-GGA-5654169 https://reactome.org/PathwayBrowser/#/R-GGA-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Gallus gallus 28815 R-GGA-5654222 https://reactome.org/PathwayBrowser/#/R-GGA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Gallus gallus 28815 R-GGA-5654224 https://reactome.org/PathwayBrowser/#/R-GGA-5654224 Activated FGFR3 binds PLCG1 IEA Gallus gallus 28815 R-GGA-5654392 https://reactome.org/PathwayBrowser/#/R-GGA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-5654397 https://reactome.org/PathwayBrowser/#/R-GGA-5654397 Activated FGFR2 phosphorylates FRS2 IEA Gallus gallus 28815 R-GGA-5654399 https://reactome.org/PathwayBrowser/#/R-GGA-5654399 Activated FGFR2 binds FRS2 IEA Gallus gallus 28815 R-GGA-5654402 https://reactome.org/PathwayBrowser/#/R-GGA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-5654404 https://reactome.org/PathwayBrowser/#/R-GGA-5654404 Activated FGFR2 binds SHC1 IEA Gallus gallus 28815 R-GGA-5654406 https://reactome.org/PathwayBrowser/#/R-GGA-5654406 Activated FGFR2:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus 28815 R-GGA-5654407 https://reactome.org/PathwayBrowser/#/R-GGA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Gallus gallus 28815 R-GGA-5654408 https://reactome.org/PathwayBrowser/#/R-GGA-5654408 Activated FGFR3 phosphorylates FRS2 IEA Gallus gallus 28815 R-GGA-5654409 https://reactome.org/PathwayBrowser/#/R-GGA-5654409 Activated FGFR3 binds FRS2 IEA Gallus gallus 28815 R-GGA-5654413 https://reactome.org/PathwayBrowser/#/R-GGA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-5654416 https://reactome.org/PathwayBrowser/#/R-GGA-5654416 Activated FGFR3:pFRS binds GRB2:SOS1 IEA Gallus gallus 28815 R-GGA-5654418 https://reactome.org/PathwayBrowser/#/R-GGA-5654418 Activated FGFR4 phosphorylates FRS2 IEA Gallus gallus 28815 R-GGA-5654422 https://reactome.org/PathwayBrowser/#/R-GGA-5654422 Activated FGFR4 binds FRS2 IEA Gallus gallus 28815 R-GGA-5654423 https://reactome.org/PathwayBrowser/#/R-GGA-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus 28815 R-GGA-5654425 https://reactome.org/PathwayBrowser/#/R-GGA-5654425 Activated FGFR4 binds SHC1 IEA Gallus gallus 28815 R-GGA-5654426 https://reactome.org/PathwayBrowser/#/R-GGA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-5654428 https://reactome.org/PathwayBrowser/#/R-GGA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Gallus gallus 28815 R-GGA-5654511 https://reactome.org/PathwayBrowser/#/R-GGA-5654511 FGFRL1 dimer binds FGFs IEA Gallus gallus 28815 R-GGA-5654515 https://reactome.org/PathwayBrowser/#/R-GGA-5654515 KAL1 binds HS IEA Gallus gallus 28815 R-GGA-5654560 https://reactome.org/PathwayBrowser/#/R-GGA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Gallus gallus 28815 R-GGA-5654562 https://reactome.org/PathwayBrowser/#/R-GGA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Gallus gallus 28815 R-GGA-5654565 https://reactome.org/PathwayBrowser/#/R-GGA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Gallus gallus 28815 R-GGA-5654566 https://reactome.org/PathwayBrowser/#/R-GGA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Gallus gallus 28815 R-GGA-5654569 https://reactome.org/PathwayBrowser/#/R-GGA-5654569 Activated FGFR1 binds FRS2 IEA Gallus gallus 28815 R-GGA-5654571 https://reactome.org/PathwayBrowser/#/R-GGA-5654571 Activated FGFR1 binds FRS3 IEA Gallus gallus 28815 R-GGA-5654573 https://reactome.org/PathwayBrowser/#/R-GGA-5654573 Activated FGFR1 binds SHC1 IEA Gallus gallus 28815 R-GGA-5654575 https://reactome.org/PathwayBrowser/#/R-GGA-5654575 Activated FGFR1 phosphorylates FRS2 IEA Gallus gallus 28815 R-GGA-5654578 https://reactome.org/PathwayBrowser/#/R-GGA-5654578 Activated FGFR1 phosphorylates FRS3 IEA Gallus gallus 28815 R-GGA-5654582 https://reactome.org/PathwayBrowser/#/R-GGA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Gallus gallus 28815 R-GGA-5654584 https://reactome.org/PathwayBrowser/#/R-GGA-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Gallus gallus 28815 R-GGA-5654586 https://reactome.org/PathwayBrowser/#/R-GGA-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Gallus gallus 28815 R-GGA-5654587 https://reactome.org/PathwayBrowser/#/R-GGA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Gallus gallus 28815 R-GGA-5654591 https://reactome.org/PathwayBrowser/#/R-GGA-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Gallus gallus 28815 R-GGA-5654592 https://reactome.org/PathwayBrowser/#/R-GGA-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Gallus gallus 28815 R-GGA-5654594 https://reactome.org/PathwayBrowser/#/R-GGA-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Gallus gallus 28815 R-GGA-5654596 https://reactome.org/PathwayBrowser/#/R-GGA-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Gallus gallus 28815 R-GGA-5654597 https://reactome.org/PathwayBrowser/#/R-GGA-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus 28815 R-GGA-5654600 https://reactome.org/PathwayBrowser/#/R-GGA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-5654603 https://reactome.org/PathwayBrowser/#/R-GGA-5654603 Activated FGFR2 binds FRS3 IEA Gallus gallus 28815 R-GGA-5654605 https://reactome.org/PathwayBrowser/#/R-GGA-5654605 Activated FGFR2 phosphorylates FRS3 IEA Gallus gallus 28815 R-GGA-5654607 https://reactome.org/PathwayBrowser/#/R-GGA-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Gallus gallus 28815 R-GGA-5654608 https://reactome.org/PathwayBrowser/#/R-GGA-5654608 Activated FGFR2:p-FRS bind to PPTN11 IEA Gallus gallus 28815 R-GGA-5654612 https://reactome.org/PathwayBrowser/#/R-GGA-5654612 Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Gallus gallus 28815 R-GGA-5654614 https://reactome.org/PathwayBrowser/#/R-GGA-5654614 Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Gallus gallus 28815 R-GGA-5654615 https://reactome.org/PathwayBrowser/#/R-GGA-5654615 Activated FGFR2:pFRS binds GRB2:SOS1 IEA Gallus gallus 28815 R-GGA-5654618 https://reactome.org/PathwayBrowser/#/R-GGA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-5654620 https://reactome.org/PathwayBrowser/#/R-GGA-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Gallus gallus 28815 R-GGA-5654622 https://reactome.org/PathwayBrowser/#/R-GGA-5654622 Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Gallus gallus 28815 R-GGA-5654623 https://reactome.org/PathwayBrowser/#/R-GGA-5654623 Activated FGFR3 binds FRS3 IEA Gallus gallus 28815 R-GGA-5654625 https://reactome.org/PathwayBrowser/#/R-GGA-5654625 Activated FGFR3 binds SHC1 IEA Gallus gallus 28815 R-GGA-5654628 https://reactome.org/PathwayBrowser/#/R-GGA-5654628 Activated FGFR3 phosphorylates FRS3 IEA Gallus gallus 28815 R-GGA-5654631 https://reactome.org/PathwayBrowser/#/R-GGA-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Gallus gallus 28815 R-GGA-5654633 https://reactome.org/PathwayBrowser/#/R-GGA-5654633 Activated FGFR3:p-FRS bind to PPTN11 IEA Gallus gallus 28815 R-GGA-5654634 https://reactome.org/PathwayBrowser/#/R-GGA-5654634 Activated FGFR3 phosphorylates SHC1 IEA Gallus gallus 28815 R-GGA-5654637 https://reactome.org/PathwayBrowser/#/R-GGA-5654637 Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Gallus gallus 28815 R-GGA-5654640 https://reactome.org/PathwayBrowser/#/R-GGA-5654640 Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Gallus gallus 28815 R-GGA-5654641 https://reactome.org/PathwayBrowser/#/R-GGA-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Gallus gallus 28815 R-GGA-5654643 https://reactome.org/PathwayBrowser/#/R-GGA-5654643 Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Gallus gallus 28815 R-GGA-5654646 https://reactome.org/PathwayBrowser/#/R-GGA-5654646 Activated FGFR3:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus 28815 R-GGA-5654647 https://reactome.org/PathwayBrowser/#/R-GGA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-5654651 https://reactome.org/PathwayBrowser/#/R-GGA-5654651 Activated FGFR4 binds FRS3 IEA Gallus gallus 28815 R-GGA-5654653 https://reactome.org/PathwayBrowser/#/R-GGA-5654653 Activated FGFR4 phosphorylates FRS3 IEA Gallus gallus 28815 R-GGA-5654655 https://reactome.org/PathwayBrowser/#/R-GGA-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Gallus gallus 28815 R-GGA-5654658 https://reactome.org/PathwayBrowser/#/R-GGA-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Gallus gallus 28815 R-GGA-5654659 https://reactome.org/PathwayBrowser/#/R-GGA-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Gallus gallus 28815 R-GGA-5654662 https://reactome.org/PathwayBrowser/#/R-GGA-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Gallus gallus 28815 R-GGA-5654663 https://reactome.org/PathwayBrowser/#/R-GGA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-5654664 https://reactome.org/PathwayBrowser/#/R-GGA-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Gallus gallus 28815 R-GGA-5654667 https://reactome.org/PathwayBrowser/#/R-GGA-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Gallus gallus 28815 R-GGA-5654669 https://reactome.org/PathwayBrowser/#/R-GGA-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Gallus gallus 28815 R-GGA-5654672 https://reactome.org/PathwayBrowser/#/R-GGA-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Gallus gallus 28815 R-GGA-5654673 https://reactome.org/PathwayBrowser/#/R-GGA-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Gallus gallus 28815 R-GGA-5654677 https://reactome.org/PathwayBrowser/#/R-GGA-5654677 CBL ubiquitinates FRS2 and FGFR2 IEA Gallus gallus 28815 R-GGA-5654679 https://reactome.org/PathwayBrowser/#/R-GGA-5654679 CBL ubiquitinates FRS2 and FGFR3 IEA Gallus gallus 28815 R-GGA-5654684 https://reactome.org/PathwayBrowser/#/R-GGA-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Gallus gallus 28815 R-GGA-5654690 https://reactome.org/PathwayBrowser/#/R-GGA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 28815 R-GGA-5654692 https://reactome.org/PathwayBrowser/#/R-GGA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 28815 R-GGA-5654697 https://reactome.org/PathwayBrowser/#/R-GGA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 28815 R-GGA-5654701 https://reactome.org/PathwayBrowser/#/R-GGA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 28815 R-GGA-5654705 https://reactome.org/PathwayBrowser/#/R-GGA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 28815 R-GGA-5654709 https://reactome.org/PathwayBrowser/#/R-GGA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 28815 R-GGA-5654714 https://reactome.org/PathwayBrowser/#/R-GGA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 28815 R-GGA-5654717 https://reactome.org/PathwayBrowser/#/R-GGA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 28815 R-GGA-5654729 https://reactome.org/PathwayBrowser/#/R-GGA-5654729 p-CBL:GRB2 binds p-FRS2:activated FGFR2 IEA Gallus gallus 28815 R-GGA-5654730 https://reactome.org/PathwayBrowser/#/R-GGA-5654730 p-CBL:GRB2 binds p-FRS2:activated FGFR3 IEA Gallus gallus 28815 R-GGA-5654734 https://reactome.org/PathwayBrowser/#/R-GGA-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Gallus gallus 28815 R-GGA-5656064 https://reactome.org/PathwayBrowser/#/R-GGA-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Gallus gallus 28815 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-8941613 https://reactome.org/PathwayBrowser/#/R-GGA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-8941618 https://reactome.org/PathwayBrowser/#/R-GGA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-8941623 https://reactome.org/PathwayBrowser/#/R-GGA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-GGA-8941628 https://reactome.org/PathwayBrowser/#/R-GGA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 28815 R-HSA-109699 https://reactome.org/PathwayBrowser/#/R-HSA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-1307955 https://reactome.org/PathwayBrowser/#/R-HSA-1307955 FGFR4 binds HS:KLB:FGF19 TAS Homo sapiens 28815 R-HSA-1307963 https://reactome.org/PathwayBrowser/#/R-HSA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 TAS Homo sapiens 28815 R-HSA-1839094 https://reactome.org/PathwayBrowser/#/R-HSA-1839094 Activated FGFR1 mutants and fusions bind PLCG1 TAS Homo sapiens 28815 R-HSA-1839098 https://reactome.org/PathwayBrowser/#/R-HSA-1839098 Activated FGFR1 mutants and fusions phosphorylate PLCG1 TAS Homo sapiens 28815 R-HSA-1839100 https://reactome.org/PathwayBrowser/#/R-HSA-1839100 p-4Y- PLCG1 dissociates from activated FGFR1 mutants and fusions TAS Homo sapiens 28815 R-HSA-190245 https://reactome.org/PathwayBrowser/#/R-HSA-190245 FGFR1b binds to FGF TAS Homo sapiens 28815 R-HSA-190256 https://reactome.org/PathwayBrowser/#/R-HSA-190256 FGFR1c binds to FGF TAS Homo sapiens 28815 R-HSA-190258 https://reactome.org/PathwayBrowser/#/R-HSA-190258 FGFR2c binds to FGF TAS Homo sapiens 28815 R-HSA-190260 https://reactome.org/PathwayBrowser/#/R-HSA-190260 FGFR2b binds to FGF TAS Homo sapiens 28815 R-HSA-190261 https://reactome.org/PathwayBrowser/#/R-HSA-190261 FGFR3c binds to FGF TAS Homo sapiens 28815 R-HSA-190263 https://reactome.org/PathwayBrowser/#/R-HSA-190263 FGFR3b binds to FGF TAS Homo sapiens 28815 R-HSA-190265 https://reactome.org/PathwayBrowser/#/R-HSA-190265 FGFR4 binds to FGF TAS Homo sapiens 28815 R-HSA-190268 https://reactome.org/PathwayBrowser/#/R-HSA-190268 FGFR1c binds to Klotho-bound FGF23 TAS Homo sapiens 28815 R-HSA-190326 https://reactome.org/PathwayBrowser/#/R-HSA-190326 Autocatalytic phosphorylation of FGFR4 TAS Homo sapiens 28815 R-HSA-190385 https://reactome.org/PathwayBrowser/#/R-HSA-190385 Autocatalytic phosphorylation of FGFR3b TAS Homo sapiens 28815 R-HSA-190388 https://reactome.org/PathwayBrowser/#/R-HSA-190388 Autocatalytic phosphorylation of FGFR3c TAS Homo sapiens 28815 R-HSA-190408 https://reactome.org/PathwayBrowser/#/R-HSA-190408 Autocatalytic phosphorylation of FGFR2b TAS Homo sapiens 28815 R-HSA-190413 https://reactome.org/PathwayBrowser/#/R-HSA-190413 Autocatalytic phosphorylation of FGFR2c TAS Homo sapiens 28815 R-HSA-190427 https://reactome.org/PathwayBrowser/#/R-HSA-190427 Autocatalytic phosphorylation of FGFR1b TAS Homo sapiens 28815 R-HSA-190429 https://reactome.org/PathwayBrowser/#/R-HSA-190429 Autocatalytic phosphorylation of FGFR1c TAS Homo sapiens 28815 R-HSA-191062 https://reactome.org/PathwayBrowser/#/R-HSA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c TAS Homo sapiens 28815 R-HSA-2012073 https://reactome.org/PathwayBrowser/#/R-HSA-2012073 Autocatalytic phosphorylation of FGFR3c P250R mutant TAS Homo sapiens 28815 R-HSA-2012074 https://reactome.org/PathwayBrowser/#/R-HSA-2012074 FGFR3c P250R mutant binds to ligand with enhanced affinity TAS Homo sapiens 28815 R-HSA-2023451 https://reactome.org/PathwayBrowser/#/R-HSA-2023451 FGFR1c P252X mutants bind ligand with enhanced affinity TAS Homo sapiens 28815 R-HSA-2023455 https://reactome.org/PathwayBrowser/#/R-HSA-2023455 Autocatalytic phosphorylation of FGFR1c P252X mutant dimers TAS Homo sapiens 28815 R-HSA-2033472 https://reactome.org/PathwayBrowser/#/R-HSA-2033472 FGFR2c mutants bind an expanded range of ligands TAS Homo sapiens 28815 R-HSA-2033474 https://reactome.org/PathwayBrowser/#/R-HSA-2033474 FGFR2b mutants bind an expanded range of ligands TAS Homo sapiens 28815 R-HSA-2033486 https://reactome.org/PathwayBrowser/#/R-HSA-2033486 Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding TAS Homo sapiens 28815 R-HSA-2033488 https://reactome.org/PathwayBrowser/#/R-HSA-2033488 Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding TAS Homo sapiens 28815 R-HSA-204485 https://reactome.org/PathwayBrowser/#/R-HSA-204485 Basigin binds CyPA TAS Homo sapiens 28815 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 28815 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 28815 R-HSA-2316434 https://reactome.org/PathwayBrowser/#/R-HSA-2316434 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 28815 R-HSA-5654147 https://reactome.org/PathwayBrowser/#/R-HSA-5654147 Activated FGFR2 phosphorylates PLCG1 TAS Homo sapiens 28815 R-HSA-5654148 https://reactome.org/PathwayBrowser/#/R-HSA-5654148 p-4Y-PLCG1 dissociates from activated FGFR3 TAS Homo sapiens 28815 R-HSA-5654149 https://reactome.org/PathwayBrowser/#/R-HSA-5654149 Activated FGFR1 phosphorylates PLCG1 TAS Homo sapiens 28815 R-HSA-5654151 https://reactome.org/PathwayBrowser/#/R-HSA-5654151 Activated FGFR4 phosphorylates PLCG1 TAS Homo sapiens 28815 R-HSA-5654157 https://reactome.org/PathwayBrowser/#/R-HSA-5654157 p-4Y-PLCG1 dissociates from activated FGFR2 TAS Homo sapiens 28815 R-HSA-5654159 https://reactome.org/PathwayBrowser/#/R-HSA-5654159 Activated FGFR2 binds PLCG1 TAS Homo sapiens 28815 R-HSA-5654163 https://reactome.org/PathwayBrowser/#/R-HSA-5654163 Activated FGFR4 binds PLCG1 TAS Homo sapiens 28815 R-HSA-5654165 https://reactome.org/PathwayBrowser/#/R-HSA-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 TAS Homo sapiens 28815 R-HSA-5654167 https://reactome.org/PathwayBrowser/#/R-HSA-5654167 Activated FGFR1 binds PLCG1 TAS Homo sapiens 28815 R-HSA-5654169 https://reactome.org/PathwayBrowser/#/R-HSA-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 TAS Homo sapiens 28815 R-HSA-5654222 https://reactome.org/PathwayBrowser/#/R-HSA-5654222 Activated FGFR3 phosphorylates PLCG1 TAS Homo sapiens 28815 R-HSA-5654224 https://reactome.org/PathwayBrowser/#/R-HSA-5654224 Activated FGFR3 binds PLCG1 TAS Homo sapiens 28815 R-HSA-5654392 https://reactome.org/PathwayBrowser/#/R-HSA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-5654397 https://reactome.org/PathwayBrowser/#/R-HSA-5654397 Activated FGFR2 phosphorylates FRS2 TAS Homo sapiens 28815 R-HSA-5654399 https://reactome.org/PathwayBrowser/#/R-HSA-5654399 Activated FGFR2 binds FRS2 TAS Homo sapiens 28815 R-HSA-5654402 https://reactome.org/PathwayBrowser/#/R-HSA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-5654404 https://reactome.org/PathwayBrowser/#/R-HSA-5654404 Activated FGFR2 binds SHC1 TAS Homo sapiens 28815 R-HSA-5654406 https://reactome.org/PathwayBrowser/#/R-HSA-5654406 Activated FGFR2:p-SHC1 binds GRB2:SOS1 TAS Homo sapiens 28815 R-HSA-5654407 https://reactome.org/PathwayBrowser/#/R-HSA-5654407 Activated FGFR2 phosphorylates SHC1 TAS Homo sapiens 28815 R-HSA-5654408 https://reactome.org/PathwayBrowser/#/R-HSA-5654408 Activated FGFR3 phosphorylates FRS2 TAS Homo sapiens 28815 R-HSA-5654409 https://reactome.org/PathwayBrowser/#/R-HSA-5654409 Activated FGFR3 binds FRS2 TAS Homo sapiens 28815 R-HSA-5654413 https://reactome.org/PathwayBrowser/#/R-HSA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-5654416 https://reactome.org/PathwayBrowser/#/R-HSA-5654416 Activated FGFR3:pFRS binds GRB2:SOS1 TAS Homo sapiens 28815 R-HSA-5654418 https://reactome.org/PathwayBrowser/#/R-HSA-5654418 Activated FGFR4 phosphorylates FRS2 TAS Homo sapiens 28815 R-HSA-5654422 https://reactome.org/PathwayBrowser/#/R-HSA-5654422 Activated FGFR4 binds FRS2 TAS Homo sapiens 28815 R-HSA-5654423 https://reactome.org/PathwayBrowser/#/R-HSA-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 TAS Homo sapiens 28815 R-HSA-5654425 https://reactome.org/PathwayBrowser/#/R-HSA-5654425 Activated FGFR4 binds SHC1 TAS Homo sapiens 28815 R-HSA-5654426 https://reactome.org/PathwayBrowser/#/R-HSA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-5654428 https://reactome.org/PathwayBrowser/#/R-HSA-5654428 Activated FGFR4 phosphorylates SHC1 TAS Homo sapiens 28815 R-HSA-5654511 https://reactome.org/PathwayBrowser/#/R-HSA-5654511 FGFRL1 dimer binds FGFs TAS Homo sapiens 28815 R-HSA-5654515 https://reactome.org/PathwayBrowser/#/R-HSA-5654515 KAL1 binds HS TAS Homo sapiens 28815 R-HSA-5654560 https://reactome.org/PathwayBrowser/#/R-HSA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. TAS Homo sapiens 28815 R-HSA-5654562 https://reactome.org/PathwayBrowser/#/R-HSA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 TAS Homo sapiens 28815 R-HSA-5654565 https://reactome.org/PathwayBrowser/#/R-HSA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. TAS Homo sapiens 28815 R-HSA-5654566 https://reactome.org/PathwayBrowser/#/R-HSA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. TAS Homo sapiens 28815 R-HSA-5654569 https://reactome.org/PathwayBrowser/#/R-HSA-5654569 Activated FGFR1 binds FRS2 TAS Homo sapiens 28815 R-HSA-5654571 https://reactome.org/PathwayBrowser/#/R-HSA-5654571 Activated FGFR1 binds FRS3 TAS Homo sapiens 28815 R-HSA-5654573 https://reactome.org/PathwayBrowser/#/R-HSA-5654573 Activated FGFR1 binds SHC1 TAS Homo sapiens 28815 R-HSA-5654575 https://reactome.org/PathwayBrowser/#/R-HSA-5654575 Activated FGFR1 phosphorylates FRS2 TAS Homo sapiens 28815 R-HSA-5654578 https://reactome.org/PathwayBrowser/#/R-HSA-5654578 Activated FGFR1 phosphorylates FRS3 TAS Homo sapiens 28815 R-HSA-5654582 https://reactome.org/PathwayBrowser/#/R-HSA-5654582 Activated FGFR1 phosphorylates SHC1 TAS Homo sapiens 28815 R-HSA-5654584 https://reactome.org/PathwayBrowser/#/R-HSA-5654584 Activated FGFR1:p-FRS bind to PPTN11 TAS Homo sapiens 28815 R-HSA-5654586 https://reactome.org/PathwayBrowser/#/R-HSA-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 TAS Homo sapiens 28815 R-HSA-5654587 https://reactome.org/PathwayBrowser/#/R-HSA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 TAS Homo sapiens 28815 R-HSA-5654591 https://reactome.org/PathwayBrowser/#/R-HSA-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA TAS Homo sapiens 28815 R-HSA-5654592 https://reactome.org/PathwayBrowser/#/R-HSA-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 TAS Homo sapiens 28815 R-HSA-5654594 https://reactome.org/PathwayBrowser/#/R-HSA-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 TAS Homo sapiens 28815 R-HSA-5654596 https://reactome.org/PathwayBrowser/#/R-HSA-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA TAS Homo sapiens 28815 R-HSA-5654597 https://reactome.org/PathwayBrowser/#/R-HSA-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 TAS Homo sapiens 28815 R-HSA-5654600 https://reactome.org/PathwayBrowser/#/R-HSA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-5654603 https://reactome.org/PathwayBrowser/#/R-HSA-5654603 Activated FGFR2 binds FRS3 TAS Homo sapiens 28815 R-HSA-5654605 https://reactome.org/PathwayBrowser/#/R-HSA-5654605 Activated FGFR2 phosphorylates FRS3 TAS Homo sapiens 28815 R-HSA-5654607 https://reactome.org/PathwayBrowser/#/R-HSA-5654607 Activated FGFR2 phosphorylates PPTN11 TAS Homo sapiens 28815 R-HSA-5654608 https://reactome.org/PathwayBrowser/#/R-HSA-5654608 Activated FGFR2:p-FRS bind to PPTN11 TAS Homo sapiens 28815 R-HSA-5654612 https://reactome.org/PathwayBrowser/#/R-HSA-5654612 Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 TAS Homo sapiens 28815 R-HSA-5654614 https://reactome.org/PathwayBrowser/#/R-HSA-5654614 Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA TAS Homo sapiens 28815 R-HSA-5654615 https://reactome.org/PathwayBrowser/#/R-HSA-5654615 Activated FGFR2:pFRS binds GRB2:SOS1 TAS Homo sapiens 28815 R-HSA-5654618 https://reactome.org/PathwayBrowser/#/R-HSA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-5654620 https://reactome.org/PathwayBrowser/#/R-HSA-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 TAS Homo sapiens 28815 R-HSA-5654622 https://reactome.org/PathwayBrowser/#/R-HSA-5654622 Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA TAS Homo sapiens 28815 R-HSA-5654623 https://reactome.org/PathwayBrowser/#/R-HSA-5654623 Activated FGFR3 binds FRS3 TAS Homo sapiens 28815 R-HSA-5654625 https://reactome.org/PathwayBrowser/#/R-HSA-5654625 Activated FGFR3 binds SHC1 TAS Homo sapiens 28815 R-HSA-5654628 https://reactome.org/PathwayBrowser/#/R-HSA-5654628 Activated FGFR3 phosphorylates FRS3 TAS Homo sapiens 28815 R-HSA-5654631 https://reactome.org/PathwayBrowser/#/R-HSA-5654631 Activated FGFR3 phosphorylates PPTN11 TAS Homo sapiens 28815 R-HSA-5654633 https://reactome.org/PathwayBrowser/#/R-HSA-5654633 Activated FGFR3:p-FRS bind to PPTN11 TAS Homo sapiens 28815 R-HSA-5654634 https://reactome.org/PathwayBrowser/#/R-HSA-5654634 Activated FGFR3 phosphorylates SHC1 TAS Homo sapiens 28815 R-HSA-5654637 https://reactome.org/PathwayBrowser/#/R-HSA-5654637 Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 TAS Homo sapiens 28815 R-HSA-5654640 https://reactome.org/PathwayBrowser/#/R-HSA-5654640 Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA TAS Homo sapiens 28815 R-HSA-5654641 https://reactome.org/PathwayBrowser/#/R-HSA-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 TAS Homo sapiens 28815 R-HSA-5654643 https://reactome.org/PathwayBrowser/#/R-HSA-5654643 Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA TAS Homo sapiens 28815 R-HSA-5654646 https://reactome.org/PathwayBrowser/#/R-HSA-5654646 Activated FGFR3:p-SHC1 binds GRB2:SOS1 TAS Homo sapiens 28815 R-HSA-5654647 https://reactome.org/PathwayBrowser/#/R-HSA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-5654651 https://reactome.org/PathwayBrowser/#/R-HSA-5654651 Activated FGFR4 binds FRS3 TAS Homo sapiens 28815 R-HSA-5654653 https://reactome.org/PathwayBrowser/#/R-HSA-5654653 Activated FGFR4 phosphorylates FRS3 TAS Homo sapiens 28815 R-HSA-5654655 https://reactome.org/PathwayBrowser/#/R-HSA-5654655 Activated FGFR4 phosphorylates PPTN11 TAS Homo sapiens 28815 R-HSA-5654658 https://reactome.org/PathwayBrowser/#/R-HSA-5654658 Activated FGFR4:p-FRS bind to PPTN11 TAS Homo sapiens 28815 R-HSA-5654659 https://reactome.org/PathwayBrowser/#/R-HSA-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 TAS Homo sapiens 28815 R-HSA-5654662 https://reactome.org/PathwayBrowser/#/R-HSA-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA TAS Homo sapiens 28815 R-HSA-5654663 https://reactome.org/PathwayBrowser/#/R-HSA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-5654664 https://reactome.org/PathwayBrowser/#/R-HSA-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 TAS Homo sapiens 28815 R-HSA-5654667 https://reactome.org/PathwayBrowser/#/R-HSA-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 TAS Homo sapiens 28815 R-HSA-5654669 https://reactome.org/PathwayBrowser/#/R-HSA-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA TAS Homo sapiens 28815 R-HSA-5654672 https://reactome.org/PathwayBrowser/#/R-HSA-5654672 CBL ubiquitinates FRS2 and FGFR1 TAS Homo sapiens 28815 R-HSA-5654673 https://reactome.org/PathwayBrowser/#/R-HSA-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 TAS Homo sapiens 28815 R-HSA-5654677 https://reactome.org/PathwayBrowser/#/R-HSA-5654677 CBL ubiquitinates FRS2 and FGFR2 TAS Homo sapiens 28815 R-HSA-5654679 https://reactome.org/PathwayBrowser/#/R-HSA-5654679 CBL ubiquitinates FRS2 and FGFR3 TAS Homo sapiens 28815 R-HSA-5654684 https://reactome.org/PathwayBrowser/#/R-HSA-5654684 CBL ubiquitinates FRS2 and FGFR4 TAS Homo sapiens 28815 R-HSA-5654690 https://reactome.org/PathwayBrowser/#/R-HSA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-5654692 https://reactome.org/PathwayBrowser/#/R-HSA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-5654697 https://reactome.org/PathwayBrowser/#/R-HSA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-5654701 https://reactome.org/PathwayBrowser/#/R-HSA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-5654705 https://reactome.org/PathwayBrowser/#/R-HSA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-5654709 https://reactome.org/PathwayBrowser/#/R-HSA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-5654714 https://reactome.org/PathwayBrowser/#/R-HSA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-5654717 https://reactome.org/PathwayBrowser/#/R-HSA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-5654729 https://reactome.org/PathwayBrowser/#/R-HSA-5654729 p-CBL:GRB2 binds p-FRS2:activated FGFR2 TAS Homo sapiens 28815 R-HSA-5654730 https://reactome.org/PathwayBrowser/#/R-HSA-5654730 p-CBL:GRB2 binds p-FRS2:activated FGFR3 TAS Homo sapiens 28815 R-HSA-5654734 https://reactome.org/PathwayBrowser/#/R-HSA-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 TAS Homo sapiens 28815 R-HSA-5654748 https://reactome.org/PathwayBrowser/#/R-HSA-5654748 p-4Y-PLCG1 dissociates from activated FGFR2 mutants TAS Homo sapiens 28815 R-HSA-5655233 https://reactome.org/PathwayBrowser/#/R-HSA-5655233 Activated FGFR2 mutants:p-FRS2 binds GRB2-SOS1 TAS Homo sapiens 28815 R-HSA-5655240 https://reactome.org/PathwayBrowser/#/R-HSA-5655240 Activated FGFR1 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 TAS Homo sapiens 28815 R-HSA-5655241 https://reactome.org/PathwayBrowser/#/R-HSA-5655241 Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-5655243 https://reactome.org/PathwayBrowser/#/R-HSA-5655243 Activated FGFR3 point and translocation mutants phosphorylate PLCG1 TAS Homo sapiens 28815 R-HSA-5655244 https://reactome.org/PathwayBrowser/#/R-HSA-5655244 Activated FGFR3 point and translocation mutants bind PLCG1 TAS Homo sapiens 28815 R-HSA-5655245 https://reactome.org/PathwayBrowser/#/R-HSA-5655245 Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA TAS Homo sapiens 28815 R-HSA-5655247 https://reactome.org/PathwayBrowser/#/R-HSA-5655247 p-4Y-PLCG1 dissociates from activated FGFR3 point and translocation mutants TAS Homo sapiens 28815 R-HSA-5655262 https://reactome.org/PathwayBrowser/#/R-HSA-5655262 Activated FGFR3 point, translocation and fusion mutants bind FRS2 TAS Homo sapiens 28815 R-HSA-5655263 https://reactome.org/PathwayBrowser/#/R-HSA-5655263 Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA TAS Homo sapiens 28815 R-HSA-5655266 https://reactome.org/PathwayBrowser/#/R-HSA-5655266 Activated FGFR1 mutants:p-FRS2 binds GRB2-SOS1 TAS Homo sapiens 28815 R-HSA-5655268 https://reactome.org/PathwayBrowser/#/R-HSA-5655268 Activated FGFR2 mutants phosphorylate FRS2 TAS Homo sapiens 28815 R-HSA-5655269 https://reactome.org/PathwayBrowser/#/R-HSA-5655269 Activated FGFR1 mutants bind FRS2 TAS Homo sapiens 28815 R-HSA-5655270 https://reactome.org/PathwayBrowser/#/R-HSA-5655270 Activated FGFR3 point, translocation and fusion mutants phosphorylate FRS2 TAS Homo sapiens 28815 R-HSA-5655277 https://reactome.org/PathwayBrowser/#/R-HSA-5655277 Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-5655278 https://reactome.org/PathwayBrowser/#/R-HSA-5655278 Activated FGFR1 mutants phosphorylate FRS2 TAS Homo sapiens 28815 R-HSA-5655285 https://reactome.org/PathwayBrowser/#/R-HSA-5655285 Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA TAS Homo sapiens 28815 R-HSA-5655289 https://reactome.org/PathwayBrowser/#/R-HSA-5655289 Activated FGFR3 point, translocation and fusion mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-5655290 https://reactome.org/PathwayBrowser/#/R-HSA-5655290 Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-5655295 https://reactome.org/PathwayBrowser/#/R-HSA-5655295 Activated FGFR3 point, translocation and fusion mutants:p-FRS2 binds GRB2-SOS1 TAS Homo sapiens 28815 R-HSA-5655301 https://reactome.org/PathwayBrowser/#/R-HSA-5655301 Activated FGFR2 mutants phosphorylate PLCG1 TAS Homo sapiens 28815 R-HSA-5655315 https://reactome.org/PathwayBrowser/#/R-HSA-5655315 Activated FGFR3 point, translocation and fusion mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 TAS Homo sapiens 28815 R-HSA-5655320 https://reactome.org/PathwayBrowser/#/R-HSA-5655320 Activated FGFR2 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 TAS Homo sapiens 28815 R-HSA-5655323 https://reactome.org/PathwayBrowser/#/R-HSA-5655323 Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 28815 R-HSA-5655326 https://reactome.org/PathwayBrowser/#/R-HSA-5655326 Activated FGFR1 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-5655339 https://reactome.org/PathwayBrowser/#/R-HSA-5655339 Activated FGFR2 mutants bind FRS2 TAS Homo sapiens 28815 R-HSA-5655343 https://reactome.org/PathwayBrowser/#/R-HSA-5655343 Activated FGFR2 mutants bind PLCG1 TAS Homo sapiens 28815 R-HSA-5656064 https://reactome.org/PathwayBrowser/#/R-HSA-5656064 Activated FGFR1 binds FLRT1,2,3 TAS Homo sapiens 28815 R-HSA-5672965 https://reactome.org/PathwayBrowser/#/R-HSA-5672965 RAS GEFs promote RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-8853320 https://reactome.org/PathwayBrowser/#/R-HSA-8853320 FGFR2IIIa TM binds ligand and full length receptors to inhibit signaling IEA Homo sapiens 28815 R-HSA-8941613 https://reactome.org/PathwayBrowser/#/R-HSA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-8941618 https://reactome.org/PathwayBrowser/#/R-HSA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-8941623 https://reactome.org/PathwayBrowser/#/R-HSA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-HSA-8941628 https://reactome.org/PathwayBrowser/#/R-HSA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 28815 R-MMU-109699 https://reactome.org/PathwayBrowser/#/R-MMU-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Mus musculus 28815 R-MMU-1307955 https://reactome.org/PathwayBrowser/#/R-MMU-1307955 FGFR4 binds HS:KLB:FGF19 IEA Mus musculus 28815 R-MMU-1307963 https://reactome.org/PathwayBrowser/#/R-MMU-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Mus musculus 28815 R-MMU-190245 https://reactome.org/PathwayBrowser/#/R-MMU-190245 FGFR1b binds to FGF IEA Mus musculus 28815 R-MMU-190256 https://reactome.org/PathwayBrowser/#/R-MMU-190256 FGFR1c binds to FGF IEA Mus musculus 28815 R-MMU-190258 https://reactome.org/PathwayBrowser/#/R-MMU-190258 FGFR2c binds to FGF IEA Mus musculus 28815 R-MMU-190260 https://reactome.org/PathwayBrowser/#/R-MMU-190260 FGFR2b binds to FGF IEA Mus musculus 28815 R-MMU-190261 https://reactome.org/PathwayBrowser/#/R-MMU-190261 FGFR3c binds to FGF IEA Mus musculus 28815 R-MMU-190263 https://reactome.org/PathwayBrowser/#/R-MMU-190263 FGFR3b binds to FGF IEA Mus musculus 28815 R-MMU-190265 https://reactome.org/PathwayBrowser/#/R-MMU-190265 FGFR4 binds to FGF IEA Mus musculus 28815 R-MMU-190268 https://reactome.org/PathwayBrowser/#/R-MMU-190268 FGFR1c binds to Klotho-bound FGF23 IEA Mus musculus 28815 R-MMU-190326 https://reactome.org/PathwayBrowser/#/R-MMU-190326 Autocatalytic phosphorylation of FGFR4 IEA Mus musculus 28815 R-MMU-190385 https://reactome.org/PathwayBrowser/#/R-MMU-190385 Autocatalytic phosphorylation of FGFR3b IEA Mus musculus 28815 R-MMU-190388 https://reactome.org/PathwayBrowser/#/R-MMU-190388 Autocatalytic phosphorylation of FGFR3c IEA Mus musculus 28815 R-MMU-190408 https://reactome.org/PathwayBrowser/#/R-MMU-190408 Autocatalytic phosphorylation of FGFR2b IEA Mus musculus 28815 R-MMU-190413 https://reactome.org/PathwayBrowser/#/R-MMU-190413 Autocatalytic phosphorylation of FGFR2c IEA Mus musculus 28815 R-MMU-190427 https://reactome.org/PathwayBrowser/#/R-MMU-190427 Autocatalytic phosphorylation of FGFR1b IEA Mus musculus 28815 R-MMU-190429 https://reactome.org/PathwayBrowser/#/R-MMU-190429 Autocatalytic phosphorylation of FGFR1c IEA Mus musculus 28815 R-MMU-191062 https://reactome.org/PathwayBrowser/#/R-MMU-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Mus musculus 28815 R-MMU-204485 https://reactome.org/PathwayBrowser/#/R-MMU-204485 Basigin binds CyPA IEA Mus musculus 28815 R-MMU-2316434 https://reactome.org/PathwayBrowser/#/R-MMU-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 28815 R-MMU-5654147 https://reactome.org/PathwayBrowser/#/R-MMU-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Mus musculus 28815 R-MMU-5654148 https://reactome.org/PathwayBrowser/#/R-MMU-5654148 p-4Y-PLCG1 dissociates from activated FGFR3 IEA Mus musculus 28815 R-MMU-5654149 https://reactome.org/PathwayBrowser/#/R-MMU-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Mus musculus 28815 R-MMU-5654151 https://reactome.org/PathwayBrowser/#/R-MMU-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Mus musculus 28815 R-MMU-5654157 https://reactome.org/PathwayBrowser/#/R-MMU-5654157 p-4Y-PLCG1 dissociates from activated FGFR2 IEA Mus musculus 28815 R-MMU-5654159 https://reactome.org/PathwayBrowser/#/R-MMU-5654159 Activated FGFR2 binds PLCG1 IEA Mus musculus 28815 R-MMU-5654163 https://reactome.org/PathwayBrowser/#/R-MMU-5654163 Activated FGFR4 binds PLCG1 IEA Mus musculus 28815 R-MMU-5654165 https://reactome.org/PathwayBrowser/#/R-MMU-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Mus musculus 28815 R-MMU-5654167 https://reactome.org/PathwayBrowser/#/R-MMU-5654167 Activated FGFR1 binds PLCG1 IEA Mus musculus 28815 R-MMU-5654169 https://reactome.org/PathwayBrowser/#/R-MMU-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Mus musculus 28815 R-MMU-5654222 https://reactome.org/PathwayBrowser/#/R-MMU-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Mus musculus 28815 R-MMU-5654224 https://reactome.org/PathwayBrowser/#/R-MMU-5654224 Activated FGFR3 binds PLCG1 IEA Mus musculus 28815 R-MMU-5654392 https://reactome.org/PathwayBrowser/#/R-MMU-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-5654397 https://reactome.org/PathwayBrowser/#/R-MMU-5654397 Activated FGFR2 phosphorylates FRS2 IEA Mus musculus 28815 R-MMU-5654399 https://reactome.org/PathwayBrowser/#/R-MMU-5654399 Activated FGFR2 binds FRS2 IEA Mus musculus 28815 R-MMU-5654402 https://reactome.org/PathwayBrowser/#/R-MMU-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-5654404 https://reactome.org/PathwayBrowser/#/R-MMU-5654404 Activated FGFR2 binds SHC1 IEA Mus musculus 28815 R-MMU-5654406 https://reactome.org/PathwayBrowser/#/R-MMU-5654406 Activated FGFR2:p-SHC1 binds GRB2:SOS1 IEA Mus musculus 28815 R-MMU-5654407 https://reactome.org/PathwayBrowser/#/R-MMU-5654407 Activated FGFR2 phosphorylates SHC1 IEA Mus musculus 28815 R-MMU-5654408 https://reactome.org/PathwayBrowser/#/R-MMU-5654408 Activated FGFR3 phosphorylates FRS2 IEA Mus musculus 28815 R-MMU-5654409 https://reactome.org/PathwayBrowser/#/R-MMU-5654409 Activated FGFR3 binds FRS2 IEA Mus musculus 28815 R-MMU-5654413 https://reactome.org/PathwayBrowser/#/R-MMU-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-5654416 https://reactome.org/PathwayBrowser/#/R-MMU-5654416 Activated FGFR3:pFRS binds GRB2:SOS1 IEA Mus musculus 28815 R-MMU-5654418 https://reactome.org/PathwayBrowser/#/R-MMU-5654418 Activated FGFR4 phosphorylates FRS2 IEA Mus musculus 28815 R-MMU-5654422 https://reactome.org/PathwayBrowser/#/R-MMU-5654422 Activated FGFR4 binds FRS2 IEA Mus musculus 28815 R-MMU-5654423 https://reactome.org/PathwayBrowser/#/R-MMU-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Mus musculus 28815 R-MMU-5654425 https://reactome.org/PathwayBrowser/#/R-MMU-5654425 Activated FGFR4 binds SHC1 IEA Mus musculus 28815 R-MMU-5654426 https://reactome.org/PathwayBrowser/#/R-MMU-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-5654428 https://reactome.org/PathwayBrowser/#/R-MMU-5654428 Activated FGFR4 phosphorylates SHC1 IEA Mus musculus 28815 R-MMU-5654511 https://reactome.org/PathwayBrowser/#/R-MMU-5654511 FGFRL1 dimer binds FGFs IEA Mus musculus 28815 R-MMU-5654560 https://reactome.org/PathwayBrowser/#/R-MMU-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Mus musculus 28815 R-MMU-5654562 https://reactome.org/PathwayBrowser/#/R-MMU-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Mus musculus 28815 R-MMU-5654565 https://reactome.org/PathwayBrowser/#/R-MMU-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Mus musculus 28815 R-MMU-5654566 https://reactome.org/PathwayBrowser/#/R-MMU-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Mus musculus 28815 R-MMU-5654569 https://reactome.org/PathwayBrowser/#/R-MMU-5654569 Activated FGFR1 binds FRS2 IEA Mus musculus 28815 R-MMU-5654571 https://reactome.org/PathwayBrowser/#/R-MMU-5654571 Activated FGFR1 binds FRS3 IEA Mus musculus 28815 R-MMU-5654573 https://reactome.org/PathwayBrowser/#/R-MMU-5654573 Activated FGFR1 binds SHC1 IEA Mus musculus 28815 R-MMU-5654575 https://reactome.org/PathwayBrowser/#/R-MMU-5654575 Activated FGFR1 phosphorylates FRS2 IEA Mus musculus 28815 R-MMU-5654578 https://reactome.org/PathwayBrowser/#/R-MMU-5654578 Activated FGFR1 phosphorylates FRS3 IEA Mus musculus 28815 R-MMU-5654582 https://reactome.org/PathwayBrowser/#/R-MMU-5654582 Activated FGFR1 phosphorylates SHC1 IEA Mus musculus 28815 R-MMU-5654584 https://reactome.org/PathwayBrowser/#/R-MMU-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Mus musculus 28815 R-MMU-5654586 https://reactome.org/PathwayBrowser/#/R-MMU-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Mus musculus 28815 R-MMU-5654587 https://reactome.org/PathwayBrowser/#/R-MMU-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Mus musculus 28815 R-MMU-5654591 https://reactome.org/PathwayBrowser/#/R-MMU-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Mus musculus 28815 R-MMU-5654592 https://reactome.org/PathwayBrowser/#/R-MMU-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Mus musculus 28815 R-MMU-5654594 https://reactome.org/PathwayBrowser/#/R-MMU-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Mus musculus 28815 R-MMU-5654596 https://reactome.org/PathwayBrowser/#/R-MMU-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Mus musculus 28815 R-MMU-5654597 https://reactome.org/PathwayBrowser/#/R-MMU-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Mus musculus 28815 R-MMU-5654600 https://reactome.org/PathwayBrowser/#/R-MMU-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-5654603 https://reactome.org/PathwayBrowser/#/R-MMU-5654603 Activated FGFR2 binds FRS3 IEA Mus musculus 28815 R-MMU-5654605 https://reactome.org/PathwayBrowser/#/R-MMU-5654605 Activated FGFR2 phosphorylates FRS3 IEA Mus musculus 28815 R-MMU-5654607 https://reactome.org/PathwayBrowser/#/R-MMU-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Mus musculus 28815 R-MMU-5654608 https://reactome.org/PathwayBrowser/#/R-MMU-5654608 Activated FGFR2:p-FRS bind to PPTN11 IEA Mus musculus 28815 R-MMU-5654612 https://reactome.org/PathwayBrowser/#/R-MMU-5654612 Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Mus musculus 28815 R-MMU-5654614 https://reactome.org/PathwayBrowser/#/R-MMU-5654614 Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Mus musculus 28815 R-MMU-5654615 https://reactome.org/PathwayBrowser/#/R-MMU-5654615 Activated FGFR2:pFRS binds GRB2:SOS1 IEA Mus musculus 28815 R-MMU-5654618 https://reactome.org/PathwayBrowser/#/R-MMU-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-5654620 https://reactome.org/PathwayBrowser/#/R-MMU-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Mus musculus 28815 R-MMU-5654622 https://reactome.org/PathwayBrowser/#/R-MMU-5654622 Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Mus musculus 28815 R-MMU-5654623 https://reactome.org/PathwayBrowser/#/R-MMU-5654623 Activated FGFR3 binds FRS3 IEA Mus musculus 28815 R-MMU-5654625 https://reactome.org/PathwayBrowser/#/R-MMU-5654625 Activated FGFR3 binds SHC1 IEA Mus musculus 28815 R-MMU-5654628 https://reactome.org/PathwayBrowser/#/R-MMU-5654628 Activated FGFR3 phosphorylates FRS3 IEA Mus musculus 28815 R-MMU-5654631 https://reactome.org/PathwayBrowser/#/R-MMU-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Mus musculus 28815 R-MMU-5654633 https://reactome.org/PathwayBrowser/#/R-MMU-5654633 Activated FGFR3:p-FRS bind to PPTN11 IEA Mus musculus 28815 R-MMU-5654634 https://reactome.org/PathwayBrowser/#/R-MMU-5654634 Activated FGFR3 phosphorylates SHC1 IEA Mus musculus 28815 R-MMU-5654637 https://reactome.org/PathwayBrowser/#/R-MMU-5654637 Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Mus musculus 28815 R-MMU-5654640 https://reactome.org/PathwayBrowser/#/R-MMU-5654640 Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Mus musculus 28815 R-MMU-5654641 https://reactome.org/PathwayBrowser/#/R-MMU-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Mus musculus 28815 R-MMU-5654643 https://reactome.org/PathwayBrowser/#/R-MMU-5654643 Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Mus musculus 28815 R-MMU-5654646 https://reactome.org/PathwayBrowser/#/R-MMU-5654646 Activated FGFR3:p-SHC1 binds GRB2:SOS1 IEA Mus musculus 28815 R-MMU-5654647 https://reactome.org/PathwayBrowser/#/R-MMU-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-5654651 https://reactome.org/PathwayBrowser/#/R-MMU-5654651 Activated FGFR4 binds FRS3 IEA Mus musculus 28815 R-MMU-5654653 https://reactome.org/PathwayBrowser/#/R-MMU-5654653 Activated FGFR4 phosphorylates FRS3 IEA Mus musculus 28815 R-MMU-5654655 https://reactome.org/PathwayBrowser/#/R-MMU-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Mus musculus 28815 R-MMU-5654658 https://reactome.org/PathwayBrowser/#/R-MMU-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Mus musculus 28815 R-MMU-5654659 https://reactome.org/PathwayBrowser/#/R-MMU-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Mus musculus 28815 R-MMU-5654662 https://reactome.org/PathwayBrowser/#/R-MMU-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Mus musculus 28815 R-MMU-5654663 https://reactome.org/PathwayBrowser/#/R-MMU-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-5654664 https://reactome.org/PathwayBrowser/#/R-MMU-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Mus musculus 28815 R-MMU-5654667 https://reactome.org/PathwayBrowser/#/R-MMU-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Mus musculus 28815 R-MMU-5654669 https://reactome.org/PathwayBrowser/#/R-MMU-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Mus musculus 28815 R-MMU-5654672 https://reactome.org/PathwayBrowser/#/R-MMU-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Mus musculus 28815 R-MMU-5654673 https://reactome.org/PathwayBrowser/#/R-MMU-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Mus musculus 28815 R-MMU-5654677 https://reactome.org/PathwayBrowser/#/R-MMU-5654677 CBL ubiquitinates FRS2 and FGFR2 IEA Mus musculus 28815 R-MMU-5654679 https://reactome.org/PathwayBrowser/#/R-MMU-5654679 CBL ubiquitinates FRS2 and FGFR3 IEA Mus musculus 28815 R-MMU-5654684 https://reactome.org/PathwayBrowser/#/R-MMU-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Mus musculus 28815 R-MMU-5654690 https://reactome.org/PathwayBrowser/#/R-MMU-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 28815 R-MMU-5654692 https://reactome.org/PathwayBrowser/#/R-MMU-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 28815 R-MMU-5654697 https://reactome.org/PathwayBrowser/#/R-MMU-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 28815 R-MMU-5654701 https://reactome.org/PathwayBrowser/#/R-MMU-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 28815 R-MMU-5654705 https://reactome.org/PathwayBrowser/#/R-MMU-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 28815 R-MMU-5654709 https://reactome.org/PathwayBrowser/#/R-MMU-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 28815 R-MMU-5654714 https://reactome.org/PathwayBrowser/#/R-MMU-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 28815 R-MMU-5654717 https://reactome.org/PathwayBrowser/#/R-MMU-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 28815 R-MMU-5654729 https://reactome.org/PathwayBrowser/#/R-MMU-5654729 p-CBL:GRB2 binds p-FRS2:activated FGFR2 IEA Mus musculus 28815 R-MMU-5654730 https://reactome.org/PathwayBrowser/#/R-MMU-5654730 p-CBL:GRB2 binds p-FRS2:activated FGFR3 IEA Mus musculus 28815 R-MMU-5654734 https://reactome.org/PathwayBrowser/#/R-MMU-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Mus musculus 28815 R-MMU-5656064 https://reactome.org/PathwayBrowser/#/R-MMU-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Mus musculus 28815 R-MMU-5672965 https://reactome.org/PathwayBrowser/#/R-MMU-5672965 RAS GEFs promote RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-8941613 https://reactome.org/PathwayBrowser/#/R-MMU-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-8941618 https://reactome.org/PathwayBrowser/#/R-MMU-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-8941623 https://reactome.org/PathwayBrowser/#/R-MMU-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 28815 R-MMU-8941628 https://reactome.org/PathwayBrowser/#/R-MMU-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 28815 R-NUL-8853328 https://reactome.org/PathwayBrowser/#/R-NUL-8853328 Mouse FGFR2 IIIa TM binds FGF1,2 and full-length receptors TAS Homo sapiens 28815 R-RNO-109699 https://reactome.org/PathwayBrowser/#/R-RNO-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Rattus norvegicus 28815 R-RNO-1307955 https://reactome.org/PathwayBrowser/#/R-RNO-1307955 FGFR4 binds HS:KLB:FGF19 IEA Rattus norvegicus 28815 R-RNO-1307963 https://reactome.org/PathwayBrowser/#/R-RNO-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Rattus norvegicus 28815 R-RNO-190245 https://reactome.org/PathwayBrowser/#/R-RNO-190245 FGFR1b binds to FGF IEA Rattus norvegicus 28815 R-RNO-190256 https://reactome.org/PathwayBrowser/#/R-RNO-190256 FGFR1c binds to FGF IEA Rattus norvegicus 28815 R-RNO-190258 https://reactome.org/PathwayBrowser/#/R-RNO-190258 FGFR2c binds to FGF IEA Rattus norvegicus 28815 R-RNO-190260 https://reactome.org/PathwayBrowser/#/R-RNO-190260 FGFR2b binds to FGF IEA Rattus norvegicus 28815 R-RNO-190261 https://reactome.org/PathwayBrowser/#/R-RNO-190261 FGFR3c binds to FGF IEA Rattus norvegicus 28815 R-RNO-190263 https://reactome.org/PathwayBrowser/#/R-RNO-190263 FGFR3b binds to FGF IEA Rattus norvegicus 28815 R-RNO-190265 https://reactome.org/PathwayBrowser/#/R-RNO-190265 FGFR4 binds to FGF IEA Rattus norvegicus 28815 R-RNO-190268 https://reactome.org/PathwayBrowser/#/R-RNO-190268 FGFR1c binds to Klotho-bound FGF23 IEA Rattus norvegicus 28815 R-RNO-190326 https://reactome.org/PathwayBrowser/#/R-RNO-190326 Autocatalytic phosphorylation of FGFR4 IEA Rattus norvegicus 28815 R-RNO-190385 https://reactome.org/PathwayBrowser/#/R-RNO-190385 Autocatalytic phosphorylation of FGFR3b IEA Rattus norvegicus 28815 R-RNO-190388 https://reactome.org/PathwayBrowser/#/R-RNO-190388 Autocatalytic phosphorylation of FGFR3c IEA Rattus norvegicus 28815 R-RNO-190408 https://reactome.org/PathwayBrowser/#/R-RNO-190408 Autocatalytic phosphorylation of FGFR2b IEA Rattus norvegicus 28815 R-RNO-190413 https://reactome.org/PathwayBrowser/#/R-RNO-190413 Autocatalytic phosphorylation of FGFR2c IEA Rattus norvegicus 28815 R-RNO-190427 https://reactome.org/PathwayBrowser/#/R-RNO-190427 Autocatalytic phosphorylation of FGFR1b IEA Rattus norvegicus 28815 R-RNO-190429 https://reactome.org/PathwayBrowser/#/R-RNO-190429 Autocatalytic phosphorylation of FGFR1c IEA Rattus norvegicus 28815 R-RNO-191062 https://reactome.org/PathwayBrowser/#/R-RNO-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Rattus norvegicus 28815 R-RNO-204485 https://reactome.org/PathwayBrowser/#/R-RNO-204485 Basigin binds CyPA IEA Rattus norvegicus 28815 R-RNO-2316434 https://reactome.org/PathwayBrowser/#/R-RNO-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 28815 R-RNO-5654147 https://reactome.org/PathwayBrowser/#/R-RNO-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Rattus norvegicus 28815 R-RNO-5654148 https://reactome.org/PathwayBrowser/#/R-RNO-5654148 p-4Y-PLCG1 dissociates from activated FGFR3 IEA Rattus norvegicus 28815 R-RNO-5654149 https://reactome.org/PathwayBrowser/#/R-RNO-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Rattus norvegicus 28815 R-RNO-5654151 https://reactome.org/PathwayBrowser/#/R-RNO-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Rattus norvegicus 28815 R-RNO-5654157 https://reactome.org/PathwayBrowser/#/R-RNO-5654157 p-4Y-PLCG1 dissociates from activated FGFR2 IEA Rattus norvegicus 28815 R-RNO-5654159 https://reactome.org/PathwayBrowser/#/R-RNO-5654159 Activated FGFR2 binds PLCG1 IEA Rattus norvegicus 28815 R-RNO-5654163 https://reactome.org/PathwayBrowser/#/R-RNO-5654163 Activated FGFR4 binds PLCG1 IEA Rattus norvegicus 28815 R-RNO-5654165 https://reactome.org/PathwayBrowser/#/R-RNO-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Rattus norvegicus 28815 R-RNO-5654167 https://reactome.org/PathwayBrowser/#/R-RNO-5654167 Activated FGFR1 binds PLCG1 IEA Rattus norvegicus 28815 R-RNO-5654169 https://reactome.org/PathwayBrowser/#/R-RNO-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Rattus norvegicus 28815 R-RNO-5654222 https://reactome.org/PathwayBrowser/#/R-RNO-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Rattus norvegicus 28815 R-RNO-5654224 https://reactome.org/PathwayBrowser/#/R-RNO-5654224 Activated FGFR3 binds PLCG1 IEA Rattus norvegicus 28815 R-RNO-5654392 https://reactome.org/PathwayBrowser/#/R-RNO-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-5654397 https://reactome.org/PathwayBrowser/#/R-RNO-5654397 Activated FGFR2 phosphorylates FRS2 IEA Rattus norvegicus 28815 R-RNO-5654399 https://reactome.org/PathwayBrowser/#/R-RNO-5654399 Activated FGFR2 binds FRS2 IEA Rattus norvegicus 28815 R-RNO-5654402 https://reactome.org/PathwayBrowser/#/R-RNO-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-5654404 https://reactome.org/PathwayBrowser/#/R-RNO-5654404 Activated FGFR2 binds SHC1 IEA Rattus norvegicus 28815 R-RNO-5654406 https://reactome.org/PathwayBrowser/#/R-RNO-5654406 Activated FGFR2:p-SHC1 binds GRB2:SOS1 IEA Rattus norvegicus 28815 R-RNO-5654407 https://reactome.org/PathwayBrowser/#/R-RNO-5654407 Activated FGFR2 phosphorylates SHC1 IEA Rattus norvegicus 28815 R-RNO-5654408 https://reactome.org/PathwayBrowser/#/R-RNO-5654408 Activated FGFR3 phosphorylates FRS2 IEA Rattus norvegicus 28815 R-RNO-5654409 https://reactome.org/PathwayBrowser/#/R-RNO-5654409 Activated FGFR3 binds FRS2 IEA Rattus norvegicus 28815 R-RNO-5654413 https://reactome.org/PathwayBrowser/#/R-RNO-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-5654416 https://reactome.org/PathwayBrowser/#/R-RNO-5654416 Activated FGFR3:pFRS binds GRB2:SOS1 IEA Rattus norvegicus 28815 R-RNO-5654418 https://reactome.org/PathwayBrowser/#/R-RNO-5654418 Activated FGFR4 phosphorylates FRS2 IEA Rattus norvegicus 28815 R-RNO-5654422 https://reactome.org/PathwayBrowser/#/R-RNO-5654422 Activated FGFR4 binds FRS2 IEA Rattus norvegicus 28815 R-RNO-5654423 https://reactome.org/PathwayBrowser/#/R-RNO-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Rattus norvegicus 28815 R-RNO-5654425 https://reactome.org/PathwayBrowser/#/R-RNO-5654425 Activated FGFR4 binds SHC1 IEA Rattus norvegicus 28815 R-RNO-5654426 https://reactome.org/PathwayBrowser/#/R-RNO-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-5654428 https://reactome.org/PathwayBrowser/#/R-RNO-5654428 Activated FGFR4 phosphorylates SHC1 IEA Rattus norvegicus 28815 R-RNO-5654511 https://reactome.org/PathwayBrowser/#/R-RNO-5654511 FGFRL1 dimer binds FGFs IEA Rattus norvegicus 28815 R-RNO-5654560 https://reactome.org/PathwayBrowser/#/R-RNO-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Rattus norvegicus 28815 R-RNO-5654562 https://reactome.org/PathwayBrowser/#/R-RNO-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Rattus norvegicus 28815 R-RNO-5654565 https://reactome.org/PathwayBrowser/#/R-RNO-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Rattus norvegicus 28815 R-RNO-5654566 https://reactome.org/PathwayBrowser/#/R-RNO-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Rattus norvegicus 28815 R-RNO-5654569 https://reactome.org/PathwayBrowser/#/R-RNO-5654569 Activated FGFR1 binds FRS2 IEA Rattus norvegicus 28815 R-RNO-5654571 https://reactome.org/PathwayBrowser/#/R-RNO-5654571 Activated FGFR1 binds FRS3 IEA Rattus norvegicus 28815 R-RNO-5654573 https://reactome.org/PathwayBrowser/#/R-RNO-5654573 Activated FGFR1 binds SHC1 IEA Rattus norvegicus 28815 R-RNO-5654575 https://reactome.org/PathwayBrowser/#/R-RNO-5654575 Activated FGFR1 phosphorylates FRS2 IEA Rattus norvegicus 28815 R-RNO-5654578 https://reactome.org/PathwayBrowser/#/R-RNO-5654578 Activated FGFR1 phosphorylates FRS3 IEA Rattus norvegicus 28815 R-RNO-5654582 https://reactome.org/PathwayBrowser/#/R-RNO-5654582 Activated FGFR1 phosphorylates SHC1 IEA Rattus norvegicus 28815 R-RNO-5654584 https://reactome.org/PathwayBrowser/#/R-RNO-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Rattus norvegicus 28815 R-RNO-5654586 https://reactome.org/PathwayBrowser/#/R-RNO-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Rattus norvegicus 28815 R-RNO-5654587 https://reactome.org/PathwayBrowser/#/R-RNO-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Rattus norvegicus 28815 R-RNO-5654591 https://reactome.org/PathwayBrowser/#/R-RNO-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Rattus norvegicus 28815 R-RNO-5654592 https://reactome.org/PathwayBrowser/#/R-RNO-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Rattus norvegicus 28815 R-RNO-5654594 https://reactome.org/PathwayBrowser/#/R-RNO-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Rattus norvegicus 28815 R-RNO-5654596 https://reactome.org/PathwayBrowser/#/R-RNO-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Rattus norvegicus 28815 R-RNO-5654597 https://reactome.org/PathwayBrowser/#/R-RNO-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Rattus norvegicus 28815 R-RNO-5654600 https://reactome.org/PathwayBrowser/#/R-RNO-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-5654603 https://reactome.org/PathwayBrowser/#/R-RNO-5654603 Activated FGFR2 binds FRS3 IEA Rattus norvegicus 28815 R-RNO-5654605 https://reactome.org/PathwayBrowser/#/R-RNO-5654605 Activated FGFR2 phosphorylates FRS3 IEA Rattus norvegicus 28815 R-RNO-5654607 https://reactome.org/PathwayBrowser/#/R-RNO-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Rattus norvegicus 28815 R-RNO-5654608 https://reactome.org/PathwayBrowser/#/R-RNO-5654608 Activated FGFR2:p-FRS bind to PPTN11 IEA Rattus norvegicus 28815 R-RNO-5654612 https://reactome.org/PathwayBrowser/#/R-RNO-5654612 Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Rattus norvegicus 28815 R-RNO-5654614 https://reactome.org/PathwayBrowser/#/R-RNO-5654614 Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Rattus norvegicus 28815 R-RNO-5654615 https://reactome.org/PathwayBrowser/#/R-RNO-5654615 Activated FGFR2:pFRS binds GRB2:SOS1 IEA Rattus norvegicus 28815 R-RNO-5654618 https://reactome.org/PathwayBrowser/#/R-RNO-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-5654620 https://reactome.org/PathwayBrowser/#/R-RNO-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Rattus norvegicus 28815 R-RNO-5654622 https://reactome.org/PathwayBrowser/#/R-RNO-5654622 Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Rattus norvegicus 28815 R-RNO-5654623 https://reactome.org/PathwayBrowser/#/R-RNO-5654623 Activated FGFR3 binds FRS3 IEA Rattus norvegicus 28815 R-RNO-5654625 https://reactome.org/PathwayBrowser/#/R-RNO-5654625 Activated FGFR3 binds SHC1 IEA Rattus norvegicus 28815 R-RNO-5654628 https://reactome.org/PathwayBrowser/#/R-RNO-5654628 Activated FGFR3 phosphorylates FRS3 IEA Rattus norvegicus 28815 R-RNO-5654631 https://reactome.org/PathwayBrowser/#/R-RNO-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Rattus norvegicus 28815 R-RNO-5654633 https://reactome.org/PathwayBrowser/#/R-RNO-5654633 Activated FGFR3:p-FRS bind to PPTN11 IEA Rattus norvegicus 28815 R-RNO-5654634 https://reactome.org/PathwayBrowser/#/R-RNO-5654634 Activated FGFR3 phosphorylates SHC1 IEA Rattus norvegicus 28815 R-RNO-5654637 https://reactome.org/PathwayBrowser/#/R-RNO-5654637 Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Rattus norvegicus 28815 R-RNO-5654640 https://reactome.org/PathwayBrowser/#/R-RNO-5654640 Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Rattus norvegicus 28815 R-RNO-5654641 https://reactome.org/PathwayBrowser/#/R-RNO-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Rattus norvegicus 28815 R-RNO-5654643 https://reactome.org/PathwayBrowser/#/R-RNO-5654643 Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Rattus norvegicus 28815 R-RNO-5654646 https://reactome.org/PathwayBrowser/#/R-RNO-5654646 Activated FGFR3:p-SHC1 binds GRB2:SOS1 IEA Rattus norvegicus 28815 R-RNO-5654647 https://reactome.org/PathwayBrowser/#/R-RNO-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-5654651 https://reactome.org/PathwayBrowser/#/R-RNO-5654651 Activated FGFR4 binds FRS3 IEA Rattus norvegicus 28815 R-RNO-5654653 https://reactome.org/PathwayBrowser/#/R-RNO-5654653 Activated FGFR4 phosphorylates FRS3 IEA Rattus norvegicus 28815 R-RNO-5654655 https://reactome.org/PathwayBrowser/#/R-RNO-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Rattus norvegicus 28815 R-RNO-5654658 https://reactome.org/PathwayBrowser/#/R-RNO-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Rattus norvegicus 28815 R-RNO-5654659 https://reactome.org/PathwayBrowser/#/R-RNO-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Rattus norvegicus 28815 R-RNO-5654662 https://reactome.org/PathwayBrowser/#/R-RNO-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Rattus norvegicus 28815 R-RNO-5654663 https://reactome.org/PathwayBrowser/#/R-RNO-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-5654664 https://reactome.org/PathwayBrowser/#/R-RNO-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Rattus norvegicus 28815 R-RNO-5654667 https://reactome.org/PathwayBrowser/#/R-RNO-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Rattus norvegicus 28815 R-RNO-5654669 https://reactome.org/PathwayBrowser/#/R-RNO-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Rattus norvegicus 28815 R-RNO-5654672 https://reactome.org/PathwayBrowser/#/R-RNO-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Rattus norvegicus 28815 R-RNO-5654673 https://reactome.org/PathwayBrowser/#/R-RNO-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Rattus norvegicus 28815 R-RNO-5654677 https://reactome.org/PathwayBrowser/#/R-RNO-5654677 CBL ubiquitinates FRS2 and FGFR2 IEA Rattus norvegicus 28815 R-RNO-5654679 https://reactome.org/PathwayBrowser/#/R-RNO-5654679 CBL ubiquitinates FRS2 and FGFR3 IEA Rattus norvegicus 28815 R-RNO-5654684 https://reactome.org/PathwayBrowser/#/R-RNO-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Rattus norvegicus 28815 R-RNO-5654690 https://reactome.org/PathwayBrowser/#/R-RNO-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 28815 R-RNO-5654692 https://reactome.org/PathwayBrowser/#/R-RNO-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 28815 R-RNO-5654697 https://reactome.org/PathwayBrowser/#/R-RNO-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 28815 R-RNO-5654701 https://reactome.org/PathwayBrowser/#/R-RNO-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 28815 R-RNO-5654705 https://reactome.org/PathwayBrowser/#/R-RNO-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 28815 R-RNO-5654709 https://reactome.org/PathwayBrowser/#/R-RNO-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 28815 R-RNO-5654714 https://reactome.org/PathwayBrowser/#/R-RNO-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 28815 R-RNO-5654717 https://reactome.org/PathwayBrowser/#/R-RNO-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 28815 R-RNO-5654729 https://reactome.org/PathwayBrowser/#/R-RNO-5654729 p-CBL:GRB2 binds p-FRS2:activated FGFR2 IEA Rattus norvegicus 28815 R-RNO-5654730 https://reactome.org/PathwayBrowser/#/R-RNO-5654730 p-CBL:GRB2 binds p-FRS2:activated FGFR3 IEA Rattus norvegicus 28815 R-RNO-5654734 https://reactome.org/PathwayBrowser/#/R-RNO-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Rattus norvegicus 28815 R-RNO-5656064 https://reactome.org/PathwayBrowser/#/R-RNO-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Rattus norvegicus 28815 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-8941613 https://reactome.org/PathwayBrowser/#/R-RNO-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-8941618 https://reactome.org/PathwayBrowser/#/R-RNO-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-8941623 https://reactome.org/PathwayBrowser/#/R-RNO-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-RNO-8941628 https://reactome.org/PathwayBrowser/#/R-RNO-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 28815 R-SSC-109699 https://reactome.org/PathwayBrowser/#/R-SSC-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Sus scrofa 28815 R-SSC-1307955 https://reactome.org/PathwayBrowser/#/R-SSC-1307955 FGFR4 binds HS:KLB:FGF19 IEA Sus scrofa 28815 R-SSC-1307963 https://reactome.org/PathwayBrowser/#/R-SSC-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Sus scrofa 28815 R-SSC-190245 https://reactome.org/PathwayBrowser/#/R-SSC-190245 FGFR1b binds to FGF IEA Sus scrofa 28815 R-SSC-190256 https://reactome.org/PathwayBrowser/#/R-SSC-190256 FGFR1c binds to FGF IEA Sus scrofa 28815 R-SSC-190265 https://reactome.org/PathwayBrowser/#/R-SSC-190265 FGFR4 binds to FGF IEA Sus scrofa 28815 R-SSC-190268 https://reactome.org/PathwayBrowser/#/R-SSC-190268 FGFR1c binds to Klotho-bound FGF23 IEA Sus scrofa 28815 R-SSC-190326 https://reactome.org/PathwayBrowser/#/R-SSC-190326 Autocatalytic phosphorylation of FGFR4 IEA Sus scrofa 28815 R-SSC-190427 https://reactome.org/PathwayBrowser/#/R-SSC-190427 Autocatalytic phosphorylation of FGFR1b IEA Sus scrofa 28815 R-SSC-190429 https://reactome.org/PathwayBrowser/#/R-SSC-190429 Autocatalytic phosphorylation of FGFR1c IEA Sus scrofa 28815 R-SSC-191062 https://reactome.org/PathwayBrowser/#/R-SSC-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Sus scrofa 28815 R-SSC-204485 https://reactome.org/PathwayBrowser/#/R-SSC-204485 Basigin binds CyPA IEA Sus scrofa 28815 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 28815 R-SSC-5654149 https://reactome.org/PathwayBrowser/#/R-SSC-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Sus scrofa 28815 R-SSC-5654151 https://reactome.org/PathwayBrowser/#/R-SSC-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Sus scrofa 28815 R-SSC-5654163 https://reactome.org/PathwayBrowser/#/R-SSC-5654163 Activated FGFR4 binds PLCG1 IEA Sus scrofa 28815 R-SSC-5654165 https://reactome.org/PathwayBrowser/#/R-SSC-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Sus scrofa 28815 R-SSC-5654167 https://reactome.org/PathwayBrowser/#/R-SSC-5654167 Activated FGFR1 binds PLCG1 IEA Sus scrofa 28815 R-SSC-5654169 https://reactome.org/PathwayBrowser/#/R-SSC-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Sus scrofa 28815 R-SSC-5654392 https://reactome.org/PathwayBrowser/#/R-SSC-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 28815 R-SSC-5654418 https://reactome.org/PathwayBrowser/#/R-SSC-5654418 Activated FGFR4 phosphorylates FRS2 IEA Sus scrofa 28815 R-SSC-5654422 https://reactome.org/PathwayBrowser/#/R-SSC-5654422 Activated FGFR4 binds FRS2 IEA Sus scrofa 28815 R-SSC-5654423 https://reactome.org/PathwayBrowser/#/R-SSC-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Sus scrofa 28815 R-SSC-5654425 https://reactome.org/PathwayBrowser/#/R-SSC-5654425 Activated FGFR4 binds SHC1 IEA Sus scrofa 28815 R-SSC-5654426 https://reactome.org/PathwayBrowser/#/R-SSC-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 28815 R-SSC-5654428 https://reactome.org/PathwayBrowser/#/R-SSC-5654428 Activated FGFR4 phosphorylates SHC1 IEA Sus scrofa 28815 R-SSC-5654511 https://reactome.org/PathwayBrowser/#/R-SSC-5654511 FGFRL1 dimer binds FGFs IEA Sus scrofa 28815 R-SSC-5654515 https://reactome.org/PathwayBrowser/#/R-SSC-5654515 KAL1 binds HS IEA Sus scrofa 28815 R-SSC-5654560 https://reactome.org/PathwayBrowser/#/R-SSC-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Sus scrofa 28815 R-SSC-5654566 https://reactome.org/PathwayBrowser/#/R-SSC-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Sus scrofa 28815 R-SSC-5654569 https://reactome.org/PathwayBrowser/#/R-SSC-5654569 Activated FGFR1 binds FRS2 IEA Sus scrofa 28815 R-SSC-5654571 https://reactome.org/PathwayBrowser/#/R-SSC-5654571 Activated FGFR1 binds FRS3 IEA Sus scrofa 28815 R-SSC-5654573 https://reactome.org/PathwayBrowser/#/R-SSC-5654573 Activated FGFR1 binds SHC1 IEA Sus scrofa 28815 R-SSC-5654575 https://reactome.org/PathwayBrowser/#/R-SSC-5654575 Activated FGFR1 phosphorylates FRS2 IEA Sus scrofa 28815 R-SSC-5654578 https://reactome.org/PathwayBrowser/#/R-SSC-5654578 Activated FGFR1 phosphorylates FRS3 IEA Sus scrofa 28815 R-SSC-5654582 https://reactome.org/PathwayBrowser/#/R-SSC-5654582 Activated FGFR1 phosphorylates SHC1 IEA Sus scrofa 28815 R-SSC-5654584 https://reactome.org/PathwayBrowser/#/R-SSC-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Sus scrofa 28815 R-SSC-5654586 https://reactome.org/PathwayBrowser/#/R-SSC-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Sus scrofa 28815 R-SSC-5654587 https://reactome.org/PathwayBrowser/#/R-SSC-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Sus scrofa 28815 R-SSC-5654591 https://reactome.org/PathwayBrowser/#/R-SSC-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Sus scrofa 28815 R-SSC-5654592 https://reactome.org/PathwayBrowser/#/R-SSC-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Sus scrofa 28815 R-SSC-5654594 https://reactome.org/PathwayBrowser/#/R-SSC-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Sus scrofa 28815 R-SSC-5654596 https://reactome.org/PathwayBrowser/#/R-SSC-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Sus scrofa 28815 R-SSC-5654597 https://reactome.org/PathwayBrowser/#/R-SSC-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Sus scrofa 28815 R-SSC-5654600 https://reactome.org/PathwayBrowser/#/R-SSC-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 28815 R-SSC-5654651 https://reactome.org/PathwayBrowser/#/R-SSC-5654651 Activated FGFR4 binds FRS3 IEA Sus scrofa 28815 R-SSC-5654653 https://reactome.org/PathwayBrowser/#/R-SSC-5654653 Activated FGFR4 phosphorylates FRS3 IEA Sus scrofa 28815 R-SSC-5654655 https://reactome.org/PathwayBrowser/#/R-SSC-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Sus scrofa 28815 R-SSC-5654658 https://reactome.org/PathwayBrowser/#/R-SSC-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Sus scrofa 28815 R-SSC-5654659 https://reactome.org/PathwayBrowser/#/R-SSC-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Sus scrofa 28815 R-SSC-5654662 https://reactome.org/PathwayBrowser/#/R-SSC-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Sus scrofa 28815 R-SSC-5654663 https://reactome.org/PathwayBrowser/#/R-SSC-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 28815 R-SSC-5654664 https://reactome.org/PathwayBrowser/#/R-SSC-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Sus scrofa 28815 R-SSC-5654667 https://reactome.org/PathwayBrowser/#/R-SSC-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Sus scrofa 28815 R-SSC-5654669 https://reactome.org/PathwayBrowser/#/R-SSC-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Sus scrofa 28815 R-SSC-5654672 https://reactome.org/PathwayBrowser/#/R-SSC-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Sus scrofa 28815 R-SSC-5654673 https://reactome.org/PathwayBrowser/#/R-SSC-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Sus scrofa 28815 R-SSC-5654684 https://reactome.org/PathwayBrowser/#/R-SSC-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Sus scrofa 28815 R-SSC-5654690 https://reactome.org/PathwayBrowser/#/R-SSC-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 28815 R-SSC-5654692 https://reactome.org/PathwayBrowser/#/R-SSC-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 28815 R-SSC-5654714 https://reactome.org/PathwayBrowser/#/R-SSC-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 28815 R-SSC-5654717 https://reactome.org/PathwayBrowser/#/R-SSC-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 28815 R-SSC-5654734 https://reactome.org/PathwayBrowser/#/R-SSC-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Sus scrofa 28815 R-SSC-5656064 https://reactome.org/PathwayBrowser/#/R-SSC-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Sus scrofa 28815 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa 28815 R-SSC-8941613 https://reactome.org/PathwayBrowser/#/R-SSC-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa 28815 R-SSC-8941623 https://reactome.org/PathwayBrowser/#/R-SSC-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa 28815 R-XTR-109699 https://reactome.org/PathwayBrowser/#/R-XTR-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Xenopus tropicalis 28815 R-XTR-1307955 https://reactome.org/PathwayBrowser/#/R-XTR-1307955 FGFR4 binds HS:KLB:FGF19 IEA Xenopus tropicalis 28815 R-XTR-1307963 https://reactome.org/PathwayBrowser/#/R-XTR-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Xenopus tropicalis 28815 R-XTR-190245 https://reactome.org/PathwayBrowser/#/R-XTR-190245 FGFR1b binds to FGF IEA Xenopus tropicalis 28815 R-XTR-190256 https://reactome.org/PathwayBrowser/#/R-XTR-190256 FGFR1c binds to FGF IEA Xenopus tropicalis 28815 R-XTR-190265 https://reactome.org/PathwayBrowser/#/R-XTR-190265 FGFR4 binds to FGF IEA Xenopus tropicalis 28815 R-XTR-190268 https://reactome.org/PathwayBrowser/#/R-XTR-190268 FGFR1c binds to Klotho-bound FGF23 IEA Xenopus tropicalis 28815 R-XTR-190326 https://reactome.org/PathwayBrowser/#/R-XTR-190326 Autocatalytic phosphorylation of FGFR4 IEA Xenopus tropicalis 28815 R-XTR-190427 https://reactome.org/PathwayBrowser/#/R-XTR-190427 Autocatalytic phosphorylation of FGFR1b IEA Xenopus tropicalis 28815 R-XTR-190429 https://reactome.org/PathwayBrowser/#/R-XTR-190429 Autocatalytic phosphorylation of FGFR1c IEA Xenopus tropicalis 28815 R-XTR-191062 https://reactome.org/PathwayBrowser/#/R-XTR-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Xenopus tropicalis 28815 R-XTR-204485 https://reactome.org/PathwayBrowser/#/R-XTR-204485 Basigin binds CyPA IEA Xenopus tropicalis 28815 R-XTR-2316434 https://reactome.org/PathwayBrowser/#/R-XTR-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 28815 R-XTR-5654149 https://reactome.org/PathwayBrowser/#/R-XTR-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Xenopus tropicalis 28815 R-XTR-5654151 https://reactome.org/PathwayBrowser/#/R-XTR-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Xenopus tropicalis 28815 R-XTR-5654163 https://reactome.org/PathwayBrowser/#/R-XTR-5654163 Activated FGFR4 binds PLCG1 IEA Xenopus tropicalis 28815 R-XTR-5654165 https://reactome.org/PathwayBrowser/#/R-XTR-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Xenopus tropicalis 28815 R-XTR-5654167 https://reactome.org/PathwayBrowser/#/R-XTR-5654167 Activated FGFR1 binds PLCG1 IEA Xenopus tropicalis 28815 R-XTR-5654169 https://reactome.org/PathwayBrowser/#/R-XTR-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Xenopus tropicalis 28815 R-XTR-5654392 https://reactome.org/PathwayBrowser/#/R-XTR-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 28815 R-XTR-5654418 https://reactome.org/PathwayBrowser/#/R-XTR-5654418 Activated FGFR4 phosphorylates FRS2 IEA Xenopus tropicalis 28815 R-XTR-5654422 https://reactome.org/PathwayBrowser/#/R-XTR-5654422 Activated FGFR4 binds FRS2 IEA Xenopus tropicalis 28815 R-XTR-5654423 https://reactome.org/PathwayBrowser/#/R-XTR-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Xenopus tropicalis 28815 R-XTR-5654426 https://reactome.org/PathwayBrowser/#/R-XTR-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 28815 R-XTR-5654428 https://reactome.org/PathwayBrowser/#/R-XTR-5654428 Activated FGFR4 phosphorylates SHC1 IEA Xenopus tropicalis 28815 R-XTR-5654511 https://reactome.org/PathwayBrowser/#/R-XTR-5654511 FGFRL1 dimer binds FGFs IEA Xenopus tropicalis 28815 R-XTR-5654515 https://reactome.org/PathwayBrowser/#/R-XTR-5654515 KAL1 binds HS IEA Xenopus tropicalis 28815 R-XTR-5654560 https://reactome.org/PathwayBrowser/#/R-XTR-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Xenopus tropicalis 28815 R-XTR-5654566 https://reactome.org/PathwayBrowser/#/R-XTR-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Xenopus tropicalis 28815 R-XTR-5654569 https://reactome.org/PathwayBrowser/#/R-XTR-5654569 Activated FGFR1 binds FRS2 IEA Xenopus tropicalis 28815 R-XTR-5654571 https://reactome.org/PathwayBrowser/#/R-XTR-5654571 Activated FGFR1 binds FRS3 IEA Xenopus tropicalis 28815 R-XTR-5654575 https://reactome.org/PathwayBrowser/#/R-XTR-5654575 Activated FGFR1 phosphorylates FRS2 IEA Xenopus tropicalis 28815 R-XTR-5654578 https://reactome.org/PathwayBrowser/#/R-XTR-5654578 Activated FGFR1 phosphorylates FRS3 IEA Xenopus tropicalis 28815 R-XTR-5654582 https://reactome.org/PathwayBrowser/#/R-XTR-5654582 Activated FGFR1 phosphorylates SHC1 IEA Xenopus tropicalis 28815 R-XTR-5654584 https://reactome.org/PathwayBrowser/#/R-XTR-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Xenopus tropicalis 28815 R-XTR-5654586 https://reactome.org/PathwayBrowser/#/R-XTR-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Xenopus tropicalis 28815 R-XTR-5654587 https://reactome.org/PathwayBrowser/#/R-XTR-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Xenopus tropicalis 28815 R-XTR-5654591 https://reactome.org/PathwayBrowser/#/R-XTR-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Xenopus tropicalis 28815 R-XTR-5654592 https://reactome.org/PathwayBrowser/#/R-XTR-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Xenopus tropicalis 28815 R-XTR-5654594 https://reactome.org/PathwayBrowser/#/R-XTR-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Xenopus tropicalis 28815 R-XTR-5654596 https://reactome.org/PathwayBrowser/#/R-XTR-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Xenopus tropicalis 28815 R-XTR-5654597 https://reactome.org/PathwayBrowser/#/R-XTR-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Xenopus tropicalis 28815 R-XTR-5654600 https://reactome.org/PathwayBrowser/#/R-XTR-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 28815 R-XTR-5654651 https://reactome.org/PathwayBrowser/#/R-XTR-5654651 Activated FGFR4 binds FRS3 IEA Xenopus tropicalis 28815 R-XTR-5654653 https://reactome.org/PathwayBrowser/#/R-XTR-5654653 Activated FGFR4 phosphorylates FRS3 IEA Xenopus tropicalis 28815 R-XTR-5654655 https://reactome.org/PathwayBrowser/#/R-XTR-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Xenopus tropicalis 28815 R-XTR-5654658 https://reactome.org/PathwayBrowser/#/R-XTR-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Xenopus tropicalis 28815 R-XTR-5654659 https://reactome.org/PathwayBrowser/#/R-XTR-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Xenopus tropicalis 28815 R-XTR-5654662 https://reactome.org/PathwayBrowser/#/R-XTR-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Xenopus tropicalis 28815 R-XTR-5654663 https://reactome.org/PathwayBrowser/#/R-XTR-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 28815 R-XTR-5654664 https://reactome.org/PathwayBrowser/#/R-XTR-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Xenopus tropicalis 28815 R-XTR-5654667 https://reactome.org/PathwayBrowser/#/R-XTR-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Xenopus tropicalis 28815 R-XTR-5654669 https://reactome.org/PathwayBrowser/#/R-XTR-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Xenopus tropicalis 28815 R-XTR-5654672 https://reactome.org/PathwayBrowser/#/R-XTR-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Xenopus tropicalis 28815 R-XTR-5654684 https://reactome.org/PathwayBrowser/#/R-XTR-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Xenopus tropicalis 28815 R-XTR-5654690 https://reactome.org/PathwayBrowser/#/R-XTR-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 28815 R-XTR-5654692 https://reactome.org/PathwayBrowser/#/R-XTR-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 28815 R-XTR-5654714 https://reactome.org/PathwayBrowser/#/R-XTR-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 28815 R-XTR-5654717 https://reactome.org/PathwayBrowser/#/R-XTR-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 28815 R-XTR-5656064 https://reactome.org/PathwayBrowser/#/R-XTR-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Xenopus tropicalis 28815 R-XTR-5672965 https://reactome.org/PathwayBrowser/#/R-XTR-5672965 RAS GEFs promote RAS nucleotide exchange IEA Xenopus tropicalis 28815 R-XTR-8941613 https://reactome.org/PathwayBrowser/#/R-XTR-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Xenopus tropicalis 28815 R-XTR-8941623 https://reactome.org/PathwayBrowser/#/R-XTR-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Xenopus tropicalis 28822 R-BTA-879585 https://reactome.org/PathwayBrowser/#/R-BTA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Bos taurus 28822 R-CEL-879585 https://reactome.org/PathwayBrowser/#/R-CEL-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Caenorhabditis elegans 28822 R-CFA-879585 https://reactome.org/PathwayBrowser/#/R-CFA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Canis familiaris 28822 R-DME-879585 https://reactome.org/PathwayBrowser/#/R-DME-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Drosophila melanogaster 28822 R-DRE-879585 https://reactome.org/PathwayBrowser/#/R-DRE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Danio rerio 28822 R-GGA-879585 https://reactome.org/PathwayBrowser/#/R-GGA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Gallus gallus 28822 R-HSA-5627891 https://reactome.org/PathwayBrowser/#/R-HSA-5627891 Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol TAS Homo sapiens 28822 R-HSA-879585 https://reactome.org/PathwayBrowser/#/R-HSA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol TAS Homo sapiens 28822 R-MMU-879585 https://reactome.org/PathwayBrowser/#/R-MMU-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Mus musculus 28822 R-RNO-879585 https://reactome.org/PathwayBrowser/#/R-RNO-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Rattus norvegicus 28822 R-SCE-879585 https://reactome.org/PathwayBrowser/#/R-SCE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Saccharomyces cerevisiae 28822 R-SSC-879585 https://reactome.org/PathwayBrowser/#/R-SSC-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Sus scrofa 28822 R-XTR-879585 https://reactome.org/PathwayBrowser/#/R-XTR-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Xenopus tropicalis 28834 R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 28834 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 28834 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 28834 R-BTA-194187 https://reactome.org/PathwayBrowser/#/R-BTA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Bos taurus 28834 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 28834 R-BTA-444654 https://reactome.org/PathwayBrowser/#/R-BTA-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Bos taurus 28834 R-BTA-5340195 https://reactome.org/PathwayBrowser/#/R-BTA-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Bos taurus 28834 R-BTA-5340251 https://reactome.org/PathwayBrowser/#/R-BTA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Bos taurus 28834 R-BTA-8873850 https://reactome.org/PathwayBrowser/#/R-BTA-8873850 STARD5 binds DCA, LCA IEA Bos taurus 28834 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 28834 R-CEL-444654 https://reactome.org/PathwayBrowser/#/R-CEL-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Caenorhabditis elegans 28834 R-CEL-8873850 https://reactome.org/PathwayBrowser/#/R-CEL-8873850 STARD5 binds DCA, LCA IEA Caenorhabditis elegans 28834 R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 28834 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 28834 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 28834 R-CFA-194187 https://reactome.org/PathwayBrowser/#/R-CFA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Canis familiaris 28834 R-CFA-444654 https://reactome.org/PathwayBrowser/#/R-CFA-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Canis familiaris 28834 R-CFA-5340195 https://reactome.org/PathwayBrowser/#/R-CFA-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Canis familiaris 28834 R-CFA-5340251 https://reactome.org/PathwayBrowser/#/R-CFA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Canis familiaris 28834 R-CFA-8873850 https://reactome.org/PathwayBrowser/#/R-CFA-8873850 STARD5 binds DCA, LCA IEA Canis familiaris 28834 R-DME-194187 https://reactome.org/PathwayBrowser/#/R-DME-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 28834 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 28834 R-DME-444654 https://reactome.org/PathwayBrowser/#/R-DME-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Drosophila melanogaster 28834 R-DME-5340195 https://reactome.org/PathwayBrowser/#/R-DME-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Drosophila melanogaster 28834 R-DME-5340251 https://reactome.org/PathwayBrowser/#/R-DME-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Drosophila melanogaster 28834 R-DRE-194187 https://reactome.org/PathwayBrowser/#/R-DRE-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Danio rerio 28834 R-DRE-5340195 https://reactome.org/PathwayBrowser/#/R-DRE-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Danio rerio 28834 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 28834 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 28834 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 28834 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus 28834 R-GGA-5340195 https://reactome.org/PathwayBrowser/#/R-GGA-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Gallus gallus 28834 R-GGA-5340251 https://reactome.org/PathwayBrowser/#/R-GGA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Gallus gallus 28834 R-GGA-8873850 https://reactome.org/PathwayBrowser/#/R-GGA-8873850 STARD5 binds DCA, LCA IEA Gallus gallus 28834 R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 28834 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 28834 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 28834 R-HSA-194187 https://reactome.org/PathwayBrowser/#/R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol TAS Homo sapiens 28834 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 28834 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 28834 R-HSA-444654 https://reactome.org/PathwayBrowser/#/R-HSA-444654 G-protein coupled bile acid receptor binds lithocholic acid TAS Homo sapiens 28834 R-HSA-5340195 https://reactome.org/PathwayBrowser/#/R-HSA-5340195 NR1H4 binds DCA, CDCA, LCHA TAS Homo sapiens 28834 R-HSA-5340251 https://reactome.org/PathwayBrowser/#/R-HSA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 TAS Homo sapiens 28834 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 28834 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 28834 R-HSA-8873850 https://reactome.org/PathwayBrowser/#/R-HSA-8873850 STARD5 binds DCA, LCA TAS Homo sapiens 28834 R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 28834 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 28834 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 28834 R-MMU-194187 https://reactome.org/PathwayBrowser/#/R-MMU-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Mus musculus 28834 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 28834 R-MMU-444654 https://reactome.org/PathwayBrowser/#/R-MMU-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Mus musculus 28834 R-MMU-5340195 https://reactome.org/PathwayBrowser/#/R-MMU-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Mus musculus 28834 R-MMU-5340251 https://reactome.org/PathwayBrowser/#/R-MMU-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Mus musculus 28834 R-MMU-8873850 https://reactome.org/PathwayBrowser/#/R-MMU-8873850 STARD5 binds DCA, LCA IEA Mus musculus 28834 R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 28834 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 28834 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 28834 R-RNO-194187 https://reactome.org/PathwayBrowser/#/R-RNO-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Rattus norvegicus 28834 R-RNO-444654 https://reactome.org/PathwayBrowser/#/R-RNO-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Rattus norvegicus 28834 R-RNO-5340195 https://reactome.org/PathwayBrowser/#/R-RNO-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Rattus norvegicus 28834 R-RNO-5340251 https://reactome.org/PathwayBrowser/#/R-RNO-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Rattus norvegicus 28834 R-RNO-8873850 https://reactome.org/PathwayBrowser/#/R-RNO-8873850 STARD5 binds DCA, LCA IEA Rattus norvegicus 28834 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 28834 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 28834 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 28834 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa 28834 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 28834 R-SSC-444654 https://reactome.org/PathwayBrowser/#/R-SSC-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Sus scrofa 28834 R-SSC-5340195 https://reactome.org/PathwayBrowser/#/R-SSC-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Sus scrofa 28834 R-SSC-5340251 https://reactome.org/PathwayBrowser/#/R-SSC-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Sus scrofa 28834 R-SSC-8873850 https://reactome.org/PathwayBrowser/#/R-SSC-8873850 STARD5 binds DCA, LCA IEA Sus scrofa 28834 R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 28834 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 28834 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 28834 R-XTR-194187 https://reactome.org/PathwayBrowser/#/R-XTR-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 28834 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 28834 R-XTR-444654 https://reactome.org/PathwayBrowser/#/R-XTR-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Xenopus tropicalis 28834 R-XTR-5340195 https://reactome.org/PathwayBrowser/#/R-XTR-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Xenopus tropicalis 28834 R-XTR-8873850 https://reactome.org/PathwayBrowser/#/R-XTR-8873850 STARD5 binds DCA, LCA IEA Xenopus tropicalis 28837 R-BTA-422104 https://reactome.org/PathwayBrowser/#/R-BTA-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Bos taurus 28837 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 28837 R-CFA-422104 https://reactome.org/PathwayBrowser/#/R-CFA-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Canis familiaris 28837 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 28837 R-DRE-422104 https://reactome.org/PathwayBrowser/#/R-DRE-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Danio rerio 28837 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 28837 R-GGA-422104 https://reactome.org/PathwayBrowser/#/R-GGA-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Gallus gallus 28837 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 28837 R-HSA-422104 https://reactome.org/PathwayBrowser/#/R-HSA-422104 Ghrelin O-acyltransferase octanoylates Proghrelin TAS Homo sapiens 28837 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 28837 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 28837 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 28837 R-MMU-422104 https://reactome.org/PathwayBrowser/#/R-MMU-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Mus musculus 28837 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 28837 R-RNO-422104 https://reactome.org/PathwayBrowser/#/R-RNO-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Rattus norvegicus 28837 R-SSC-422104 https://reactome.org/PathwayBrowser/#/R-SSC-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Sus scrofa 28837 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 28847 R-HSA-166726 https://reactome.org/PathwayBrowser/#/R-HSA-166726 Activation of MASPs TAS Homo sapiens 28847 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens 28847 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens 28847 R-HSA-2855077 https://reactome.org/PathwayBrowser/#/R-HSA-2855077 Ficolin-3 binds to molecular patterns on the target cell surface TAS Homo sapiens 28855 R-ECO-1222667 https://reactome.org/PathwayBrowser/#/R-ECO-1222667 Iron is reduced and separates from enterobactin TAS Escherichia coli 28857 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 28857 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 28857 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 28857 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 28857 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 28857 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 28857 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 28857 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 28857 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 28858 R-BTA-1855202 https://reactome.org/PathwayBrowser/#/R-BTA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Bos taurus 28858 R-BTA-1855232 https://reactome.org/PathwayBrowser/#/R-BTA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Bos taurus 28858 R-CEL-1855202 https://reactome.org/PathwayBrowser/#/R-CEL-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Caenorhabditis elegans 28858 R-CFA-1855202 https://reactome.org/PathwayBrowser/#/R-CFA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Canis familiaris 28858 R-CFA-1855232 https://reactome.org/PathwayBrowser/#/R-CFA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Canis familiaris 28858 R-DDI-1855232 https://reactome.org/PathwayBrowser/#/R-DDI-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Dictyostelium discoideum 28858 R-DME-1855202 https://reactome.org/PathwayBrowser/#/R-DME-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Drosophila melanogaster 28858 R-DME-1855232 https://reactome.org/PathwayBrowser/#/R-DME-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Drosophila melanogaster 28858 R-DRE-1855202 https://reactome.org/PathwayBrowser/#/R-DRE-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Danio rerio 28858 R-GGA-1855202 https://reactome.org/PathwayBrowser/#/R-GGA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Gallus gallus 28858 R-GGA-1855232 https://reactome.org/PathwayBrowser/#/R-GGA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Gallus gallus 28858 R-HSA-1855202 https://reactome.org/PathwayBrowser/#/R-HSA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol TAS Homo sapiens 28858 R-HSA-1855232 https://reactome.org/PathwayBrowser/#/R-HSA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol TAS Homo sapiens 28858 R-MMU-1855202 https://reactome.org/PathwayBrowser/#/R-MMU-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Mus musculus 28858 R-MMU-1855232 https://reactome.org/PathwayBrowser/#/R-MMU-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Mus musculus 28858 R-RNO-1855202 https://reactome.org/PathwayBrowser/#/R-RNO-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Rattus norvegicus 28858 R-RNO-1855232 https://reactome.org/PathwayBrowser/#/R-RNO-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Rattus norvegicus 28858 R-SSC-1855202 https://reactome.org/PathwayBrowser/#/R-SSC-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Sus scrofa 28858 R-SSC-1855232 https://reactome.org/PathwayBrowser/#/R-SSC-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Sus scrofa 28858 R-XTR-1855202 https://reactome.org/PathwayBrowser/#/R-XTR-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Xenopus tropicalis 28866 R-BTA-879585 https://reactome.org/PathwayBrowser/#/R-BTA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Bos taurus 28866 R-CEL-879585 https://reactome.org/PathwayBrowser/#/R-CEL-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Caenorhabditis elegans 28866 R-CFA-879585 https://reactome.org/PathwayBrowser/#/R-CFA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Canis familiaris 28866 R-DME-879585 https://reactome.org/PathwayBrowser/#/R-DME-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Drosophila melanogaster 28866 R-DRE-879585 https://reactome.org/PathwayBrowser/#/R-DRE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Danio rerio 28866 R-GGA-879585 https://reactome.org/PathwayBrowser/#/R-GGA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Gallus gallus 28866 R-HSA-5627891 https://reactome.org/PathwayBrowser/#/R-HSA-5627891 Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol TAS Homo sapiens 28866 R-HSA-879585 https://reactome.org/PathwayBrowser/#/R-HSA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol TAS Homo sapiens 28866 R-MMU-879585 https://reactome.org/PathwayBrowser/#/R-MMU-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Mus musculus 28866 R-RNO-879585 https://reactome.org/PathwayBrowser/#/R-RNO-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Rattus norvegicus 28866 R-SCE-879585 https://reactome.org/PathwayBrowser/#/R-SCE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Saccharomyces cerevisiae 28866 R-SSC-879585 https://reactome.org/PathwayBrowser/#/R-SSC-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Sus scrofa 28866 R-XTR-879585 https://reactome.org/PathwayBrowser/#/R-XTR-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Xenopus tropicalis 28867 R-BTA-390284 https://reactome.org/PathwayBrowser/#/R-BTA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Bos taurus 28867 R-CEL-390284 https://reactome.org/PathwayBrowser/#/R-CEL-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Caenorhabditis elegans 28867 R-CFA-390284 https://reactome.org/PathwayBrowser/#/R-CFA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Canis familiaris 28867 R-DME-390284 https://reactome.org/PathwayBrowser/#/R-DME-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Drosophila melanogaster 28867 R-DRE-390284 https://reactome.org/PathwayBrowser/#/R-DRE-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Danio rerio 28867 R-GGA-390284 https://reactome.org/PathwayBrowser/#/R-GGA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Gallus gallus 28867 R-HSA-390284 https://reactome.org/PathwayBrowser/#/R-HSA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH TAS Homo sapiens 28867 R-MMU-390284 https://reactome.org/PathwayBrowser/#/R-MMU-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Mus musculus 28867 R-RNO-390284 https://reactome.org/PathwayBrowser/#/R-RNO-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Rattus norvegicus 28867 R-SSC-390284 https://reactome.org/PathwayBrowser/#/R-SSC-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Sus scrofa 28867 R-XTR-390284 https://reactome.org/PathwayBrowser/#/R-XTR-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Xenopus tropicalis 28868 R-BTA-1606583 https://reactome.org/PathwayBrowser/#/R-BTA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Bos taurus 28868 R-BTA-1606602 https://reactome.org/PathwayBrowser/#/R-BTA-1606602 ASAH1 hydrolyzes ceramide IEA Bos taurus 28868 R-BTA-166214 https://reactome.org/PathwayBrowser/#/R-BTA-166214 FA anion flip-flops to the opposite surface IEA Bos taurus 28868 R-BTA-166220 https://reactome.org/PathwayBrowser/#/R-BTA-166220 FA anion diffuses laterally to UCP IEA Bos taurus 28868 R-BTA-166387 https://reactome.org/PathwayBrowser/#/R-BTA-166387 The FA anion diffuses away laterally from UCP IEA Bos taurus 28868 R-BTA-428205 https://reactome.org/PathwayBrowser/#/R-BTA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Bos taurus 28868 R-BTA-428231 https://reactome.org/PathwayBrowser/#/R-BTA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Bos taurus 28868 R-BTA-428262 https://reactome.org/PathwayBrowser/#/R-BTA-428262 ACER3 hydrolyzes phytoceramide IEA Bos taurus 28868 R-BTA-5694485 https://reactome.org/PathwayBrowser/#/R-BTA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Bos taurus 28868 R-CEL-1606602 https://reactome.org/PathwayBrowser/#/R-CEL-1606602 ASAH1 hydrolyzes ceramide IEA Caenorhabditis elegans 28868 R-CEL-166214 https://reactome.org/PathwayBrowser/#/R-CEL-166214 FA anion flip-flops to the opposite surface IEA Caenorhabditis elegans 28868 R-CEL-166220 https://reactome.org/PathwayBrowser/#/R-CEL-166220 FA anion diffuses laterally to UCP IEA Caenorhabditis elegans 28868 R-CEL-166387 https://reactome.org/PathwayBrowser/#/R-CEL-166387 The FA anion diffuses away laterally from UCP IEA Caenorhabditis elegans 28868 R-CEL-428205 https://reactome.org/PathwayBrowser/#/R-CEL-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Caenorhabditis elegans 28868 R-CEL-428231 https://reactome.org/PathwayBrowser/#/R-CEL-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Caenorhabditis elegans 28868 R-CEL-5694485 https://reactome.org/PathwayBrowser/#/R-CEL-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Caenorhabditis elegans 28868 R-CFA-1606583 https://reactome.org/PathwayBrowser/#/R-CFA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Canis familiaris 28868 R-CFA-1606602 https://reactome.org/PathwayBrowser/#/R-CFA-1606602 ASAH1 hydrolyzes ceramide IEA Canis familiaris 28868 R-CFA-166214 https://reactome.org/PathwayBrowser/#/R-CFA-166214 FA anion flip-flops to the opposite surface IEA Canis familiaris 28868 R-CFA-166220 https://reactome.org/PathwayBrowser/#/R-CFA-166220 FA anion diffuses laterally to UCP IEA Canis familiaris 28868 R-CFA-166387 https://reactome.org/PathwayBrowser/#/R-CFA-166387 The FA anion diffuses away laterally from UCP IEA Canis familiaris 28868 R-CFA-428205 https://reactome.org/PathwayBrowser/#/R-CFA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Canis familiaris 28868 R-CFA-428231 https://reactome.org/PathwayBrowser/#/R-CFA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Canis familiaris 28868 R-CFA-428262 https://reactome.org/PathwayBrowser/#/R-CFA-428262 ACER3 hydrolyzes phytoceramide IEA Canis familiaris 28868 R-CFA-5694485 https://reactome.org/PathwayBrowser/#/R-CFA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Canis familiaris 28868 R-DDI-1606583 https://reactome.org/PathwayBrowser/#/R-DDI-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Dictyostelium discoideum 28868 R-DDI-428262 https://reactome.org/PathwayBrowser/#/R-DDI-428262 ACER3 hydrolyzes phytoceramide IEA Dictyostelium discoideum 28868 R-DDI-5694485 https://reactome.org/PathwayBrowser/#/R-DDI-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Dictyostelium discoideum 28868 R-DME-1606583 https://reactome.org/PathwayBrowser/#/R-DME-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Drosophila melanogaster 28868 R-DME-166214 https://reactome.org/PathwayBrowser/#/R-DME-166214 FA anion flip-flops to the opposite surface IEA Drosophila melanogaster 28868 R-DME-166220 https://reactome.org/PathwayBrowser/#/R-DME-166220 FA anion diffuses laterally to UCP IEA Drosophila melanogaster 28868 R-DME-166387 https://reactome.org/PathwayBrowser/#/R-DME-166387 The FA anion diffuses away laterally from UCP IEA Drosophila melanogaster 28868 R-DME-428205 https://reactome.org/PathwayBrowser/#/R-DME-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Drosophila melanogaster 28868 R-DME-428231 https://reactome.org/PathwayBrowser/#/R-DME-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Drosophila melanogaster 28868 R-DME-5694485 https://reactome.org/PathwayBrowser/#/R-DME-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Drosophila melanogaster 28868 R-DRE-1606583 https://reactome.org/PathwayBrowser/#/R-DRE-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Danio rerio 28868 R-DRE-166214 https://reactome.org/PathwayBrowser/#/R-DRE-166214 FA anion flip-flops to the opposite surface IEA Danio rerio 28868 R-DRE-166220 https://reactome.org/PathwayBrowser/#/R-DRE-166220 FA anion diffuses laterally to UCP IEA Danio rerio 28868 R-DRE-166387 https://reactome.org/PathwayBrowser/#/R-DRE-166387 The FA anion diffuses away laterally from UCP IEA Danio rerio 28868 R-DRE-428231 https://reactome.org/PathwayBrowser/#/R-DRE-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Danio rerio 28868 R-DRE-5694485 https://reactome.org/PathwayBrowser/#/R-DRE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Danio rerio 28868 R-GGA-1606583 https://reactome.org/PathwayBrowser/#/R-GGA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Gallus gallus 28868 R-GGA-1606602 https://reactome.org/PathwayBrowser/#/R-GGA-1606602 ASAH1 hydrolyzes ceramide IEA Gallus gallus 28868 R-GGA-166214 https://reactome.org/PathwayBrowser/#/R-GGA-166214 FA anion flip-flops to the opposite surface IEA Gallus gallus 28868 R-GGA-166220 https://reactome.org/PathwayBrowser/#/R-GGA-166220 FA anion diffuses laterally to UCP IEA Gallus gallus 28868 R-GGA-166387 https://reactome.org/PathwayBrowser/#/R-GGA-166387 The FA anion diffuses away laterally from UCP IEA Gallus gallus 28868 R-GGA-428205 https://reactome.org/PathwayBrowser/#/R-GGA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Gallus gallus 28868 R-GGA-428231 https://reactome.org/PathwayBrowser/#/R-GGA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Gallus gallus 28868 R-GGA-428262 https://reactome.org/PathwayBrowser/#/R-GGA-428262 ACER3 hydrolyzes phytoceramide IEA Gallus gallus 28868 R-GGA-5694485 https://reactome.org/PathwayBrowser/#/R-GGA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Gallus gallus 28868 R-HSA-1222341 https://reactome.org/PathwayBrowser/#/R-HSA-1222341 H2O2 gets scavenged by unsaturated lipid TAS Homo sapiens 28868 R-HSA-1606583 https://reactome.org/PathwayBrowser/#/R-HSA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) TAS Homo sapiens 28868 R-HSA-1606602 https://reactome.org/PathwayBrowser/#/R-HSA-1606602 ASAH1 hydrolyzes ceramide TAS Homo sapiens 28868 R-HSA-166214 https://reactome.org/PathwayBrowser/#/R-HSA-166214 FA anion flip-flops to the opposite surface TAS Homo sapiens 28868 R-HSA-166219 https://reactome.org/PathwayBrowser/#/R-HSA-166219 FA anion picks up a proton TAS Homo sapiens 28868 R-HSA-166220 https://reactome.org/PathwayBrowser/#/R-HSA-166220 FA anion diffuses laterally to UCP TAS Homo sapiens 28868 R-HSA-166223 https://reactome.org/PathwayBrowser/#/R-HSA-166223 The proton is delivered to the matrix side TAS Homo sapiens 28868 R-HSA-166387 https://reactome.org/PathwayBrowser/#/R-HSA-166387 The FA anion diffuses away laterally from UCP TAS Homo sapiens 28868 R-HSA-428205 https://reactome.org/PathwayBrowser/#/R-HSA-428205 ACER2 hydrolyzes ceramide (Golgi) TAS Homo sapiens 28868 R-HSA-428231 https://reactome.org/PathwayBrowser/#/R-HSA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) TAS Homo sapiens 28868 R-HSA-428262 https://reactome.org/PathwayBrowser/#/R-HSA-428262 ACER3 hydrolyzes phytoceramide TAS Homo sapiens 28868 R-HSA-5694485 https://reactome.org/PathwayBrowser/#/R-HSA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC TAS Homo sapiens 28868 R-HSA-6789042 https://reactome.org/PathwayBrowser/#/R-HSA-6789042 Hydroxyl-initiated lipid peroxidation TAS Homo sapiens 28868 R-HSA-6789218 https://reactome.org/PathwayBrowser/#/R-HSA-6789218 Hypochlorous acid (HOCl) reacts with unsaturated lipid to form lipid chlorohydrins TAS Homo sapiens 28868 R-MMU-1606583 https://reactome.org/PathwayBrowser/#/R-MMU-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Mus musculus 28868 R-MMU-1606602 https://reactome.org/PathwayBrowser/#/R-MMU-1606602 ASAH1 hydrolyzes ceramide IEA Mus musculus 28868 R-MMU-166214 https://reactome.org/PathwayBrowser/#/R-MMU-166214 FA anion flip-flops to the opposite surface IEA Mus musculus 28868 R-MMU-166220 https://reactome.org/PathwayBrowser/#/R-MMU-166220 FA anion diffuses laterally to UCP IEA Mus musculus 28868 R-MMU-166387 https://reactome.org/PathwayBrowser/#/R-MMU-166387 The FA anion diffuses away laterally from UCP IEA Mus musculus 28868 R-MMU-428205 https://reactome.org/PathwayBrowser/#/R-MMU-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Mus musculus 28868 R-MMU-428231 https://reactome.org/PathwayBrowser/#/R-MMU-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Mus musculus 28868 R-MMU-428262 https://reactome.org/PathwayBrowser/#/R-MMU-428262 ACER3 hydrolyzes phytoceramide IEA Mus musculus 28868 R-MMU-5694485 https://reactome.org/PathwayBrowser/#/R-MMU-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Mus musculus 28868 R-RNO-1606583 https://reactome.org/PathwayBrowser/#/R-RNO-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Rattus norvegicus 28868 R-RNO-1606602 https://reactome.org/PathwayBrowser/#/R-RNO-1606602 ASAH1 hydrolyzes ceramide IEA Rattus norvegicus 28868 R-RNO-166214 https://reactome.org/PathwayBrowser/#/R-RNO-166214 FA anion flip-flops to the opposite surface IEA Rattus norvegicus 28868 R-RNO-166220 https://reactome.org/PathwayBrowser/#/R-RNO-166220 FA anion diffuses laterally to UCP IEA Rattus norvegicus 28868 R-RNO-166387 https://reactome.org/PathwayBrowser/#/R-RNO-166387 The FA anion diffuses away laterally from UCP IEA Rattus norvegicus 28868 R-RNO-428205 https://reactome.org/PathwayBrowser/#/R-RNO-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Rattus norvegicus 28868 R-RNO-428231 https://reactome.org/PathwayBrowser/#/R-RNO-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Rattus norvegicus 28868 R-RNO-428262 https://reactome.org/PathwayBrowser/#/R-RNO-428262 ACER3 hydrolyzes phytoceramide IEA Rattus norvegicus 28868 R-RNO-5694485 https://reactome.org/PathwayBrowser/#/R-RNO-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Rattus norvegicus 28868 R-SCE-428262 https://reactome.org/PathwayBrowser/#/R-SCE-428262 ACER3 hydrolyzes phytoceramide IEA Saccharomyces cerevisiae 28868 R-SCE-5694485 https://reactome.org/PathwayBrowser/#/R-SCE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Saccharomyces cerevisiae 28868 R-SSC-1606583 https://reactome.org/PathwayBrowser/#/R-SSC-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Sus scrofa 28868 R-SSC-1606602 https://reactome.org/PathwayBrowser/#/R-SSC-1606602 ASAH1 hydrolyzes ceramide IEA Sus scrofa 28868 R-SSC-166214 https://reactome.org/PathwayBrowser/#/R-SSC-166214 FA anion flip-flops to the opposite surface IEA Sus scrofa 28868 R-SSC-166220 https://reactome.org/PathwayBrowser/#/R-SSC-166220 FA anion diffuses laterally to UCP IEA Sus scrofa 28868 R-SSC-166387 https://reactome.org/PathwayBrowser/#/R-SSC-166387 The FA anion diffuses away laterally from UCP IEA Sus scrofa 28868 R-SSC-428205 https://reactome.org/PathwayBrowser/#/R-SSC-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Sus scrofa 28868 R-SSC-428231 https://reactome.org/PathwayBrowser/#/R-SSC-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Sus scrofa 28868 R-SSC-428262 https://reactome.org/PathwayBrowser/#/R-SSC-428262 ACER3 hydrolyzes phytoceramide IEA Sus scrofa 28868 R-SSC-5694485 https://reactome.org/PathwayBrowser/#/R-SSC-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Sus scrofa 28868 R-XTR-1606583 https://reactome.org/PathwayBrowser/#/R-XTR-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Xenopus tropicalis 28868 R-XTR-166214 https://reactome.org/PathwayBrowser/#/R-XTR-166214 FA anion flip-flops to the opposite surface IEA Xenopus tropicalis 28868 R-XTR-166220 https://reactome.org/PathwayBrowser/#/R-XTR-166220 FA anion diffuses laterally to UCP IEA Xenopus tropicalis 28868 R-XTR-166387 https://reactome.org/PathwayBrowser/#/R-XTR-166387 The FA anion diffuses away laterally from UCP IEA Xenopus tropicalis 28868 R-XTR-428205 https://reactome.org/PathwayBrowser/#/R-XTR-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Xenopus tropicalis 28868 R-XTR-428231 https://reactome.org/PathwayBrowser/#/R-XTR-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Xenopus tropicalis 28868 R-XTR-428262 https://reactome.org/PathwayBrowser/#/R-XTR-428262 ACER3 hydrolyzes phytoceramide IEA Xenopus tropicalis 28868 R-XTR-5694485 https://reactome.org/PathwayBrowser/#/R-XTR-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Xenopus tropicalis 28869 R-BTA-6806674 https://reactome.org/PathwayBrowser/#/R-BTA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Bos taurus 28869 R-CFA-6806674 https://reactome.org/PathwayBrowser/#/R-CFA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Canis familiaris 28869 R-DDI-6806674 https://reactome.org/PathwayBrowser/#/R-DDI-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Dictyostelium discoideum 28869 R-DME-6806674 https://reactome.org/PathwayBrowser/#/R-DME-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 28869 R-DRE-6806674 https://reactome.org/PathwayBrowser/#/R-DRE-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Danio rerio 28869 R-GGA-6806674 https://reactome.org/PathwayBrowser/#/R-GGA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Gallus gallus 28869 R-HSA-6806674 https://reactome.org/PathwayBrowser/#/R-HSA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) TAS Homo sapiens 28869 R-MMU-6806674 https://reactome.org/PathwayBrowser/#/R-MMU-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Mus musculus 28869 R-RNO-6806674 https://reactome.org/PathwayBrowser/#/R-RNO-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 28869 R-SSC-6806674 https://reactome.org/PathwayBrowser/#/R-SSC-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Sus scrofa 28869 R-XTR-6806674 https://reactome.org/PathwayBrowser/#/R-XTR-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 28874 R-BTA-8850326 https://reactome.org/PathwayBrowser/#/R-BTA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Bos taurus 28874 R-CFA-8850326 https://reactome.org/PathwayBrowser/#/R-CFA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Canis familiaris 28874 R-GGA-8850326 https://reactome.org/PathwayBrowser/#/R-GGA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Gallus gallus 28874 R-HSA-8850326 https://reactome.org/PathwayBrowser/#/R-HSA-8850326 TCR binds self-lipid-based antigen via CD1 TAS Homo sapiens 28874 R-MMU-8850326 https://reactome.org/PathwayBrowser/#/R-MMU-8850326 TCR binds self-lipid-based antigen via CD1 IEA Mus musculus 28874 R-RNO-8850326 https://reactome.org/PathwayBrowser/#/R-RNO-8850326 TCR binds self-lipid-based antigen via CD1 IEA Rattus norvegicus 28874 R-SSC-8850326 https://reactome.org/PathwayBrowser/#/R-SSC-8850326 TCR binds self-lipid-based antigen via CD1 IEA Sus scrofa 28875 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 28875 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 28875 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 28875 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 28875 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 28875 R-BTA-879585 https://reactome.org/PathwayBrowser/#/R-BTA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Bos taurus 28875 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 28875 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 28875 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 28875 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 28875 R-CEL-879585 https://reactome.org/PathwayBrowser/#/R-CEL-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Caenorhabditis elegans 28875 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 28875 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 28875 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 28875 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 28875 R-CFA-879585 https://reactome.org/PathwayBrowser/#/R-CFA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Canis familiaris 28875 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 28875 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 28875 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 28875 R-DME-879585 https://reactome.org/PathwayBrowser/#/R-DME-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Drosophila melanogaster 28875 R-DRE-879585 https://reactome.org/PathwayBrowser/#/R-DRE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Danio rerio 28875 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 28875 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 28875 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 28875 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 28875 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 28875 R-GGA-879585 https://reactome.org/PathwayBrowser/#/R-GGA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Gallus gallus 28875 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 28875 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 28875 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 28875 R-HSA-5627891 https://reactome.org/PathwayBrowser/#/R-HSA-5627891 Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol TAS Homo sapiens 28875 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 28875 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 28875 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 28875 R-HSA-879585 https://reactome.org/PathwayBrowser/#/R-HSA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol TAS Homo sapiens 28875 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 28875 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 28875 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 28875 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 28875 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 28875 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 28875 R-MMU-879585 https://reactome.org/PathwayBrowser/#/R-MMU-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Mus musculus 28875 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 28875 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 28875 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 28875 R-RNO-879585 https://reactome.org/PathwayBrowser/#/R-RNO-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Rattus norvegicus 28875 R-SCE-879585 https://reactome.org/PathwayBrowser/#/R-SCE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Saccharomyces cerevisiae 28875 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 28875 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 28875 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 28875 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 28875 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 28875 R-SSC-879585 https://reactome.org/PathwayBrowser/#/R-SSC-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Sus scrofa 28875 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 28875 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 28875 R-XTR-879585 https://reactome.org/PathwayBrowser/#/R-XTR-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Xenopus tropicalis 28878 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 28878 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 28878 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 28878 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 28878 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 28878 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 28878 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 28878 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 28878 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 28879 R-BTA-1006169 https://reactome.org/PathwayBrowser/#/R-BTA-1006169 Factor H binds host cell surface markers IEA Bos taurus 28879 R-BTA-166726 https://reactome.org/PathwayBrowser/#/R-BTA-166726 Activation of MASPs IEA Bos taurus 28879 R-BTA-166753 https://reactome.org/PathwayBrowser/#/R-BTA-166753 Conversion of C4 into C4a and C4b IEA Bos taurus 28879 R-BTA-166792 https://reactome.org/PathwayBrowser/#/R-BTA-166792 Conversion of C2 into C2a and C2b IEA Bos taurus 28879 R-BTA-2855125 https://reactome.org/PathwayBrowser/#/R-BTA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Bos taurus 28879 R-BTA-5685607 https://reactome.org/PathwayBrowser/#/R-BTA-5685607 Sialic acid binds SIGLEC IEA Bos taurus 28879 R-BTA-977363 https://reactome.org/PathwayBrowser/#/R-BTA-977363 Factor H binds to C3bBb IEA Bos taurus 28879 R-BTA-981728 https://reactome.org/PathwayBrowser/#/R-BTA-981728 Factor H binds to membrane-associated C3b IEA Bos taurus 28879 R-CFA-1006169 https://reactome.org/PathwayBrowser/#/R-CFA-1006169 Factor H binds host cell surface markers IEA Canis familiaris 28879 R-CFA-166726 https://reactome.org/PathwayBrowser/#/R-CFA-166726 Activation of MASPs IEA Canis familiaris 28879 R-CFA-166753 https://reactome.org/PathwayBrowser/#/R-CFA-166753 Conversion of C4 into C4a and C4b IEA Canis familiaris 28879 R-CFA-166792 https://reactome.org/PathwayBrowser/#/R-CFA-166792 Conversion of C2 into C2a and C2b IEA Canis familiaris 28879 R-CFA-2855125 https://reactome.org/PathwayBrowser/#/R-CFA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Canis familiaris 28879 R-CFA-422454 https://reactome.org/PathwayBrowser/#/R-CFA-422454 Polysialylation of NCAM1 IEA Canis familiaris 28879 R-CFA-5685607 https://reactome.org/PathwayBrowser/#/R-CFA-5685607 Sialic acid binds SIGLEC IEA Canis familiaris 28879 R-CFA-977363 https://reactome.org/PathwayBrowser/#/R-CFA-977363 Factor H binds to C3bBb IEA Canis familiaris 28879 R-CFA-981728 https://reactome.org/PathwayBrowser/#/R-CFA-981728 Factor H binds to membrane-associated C3b IEA Canis familiaris 28879 R-DRE-1006169 https://reactome.org/PathwayBrowser/#/R-DRE-1006169 Factor H binds host cell surface markers IEA Danio rerio 28879 R-DRE-5685607 https://reactome.org/PathwayBrowser/#/R-DRE-5685607 Sialic acid binds SIGLEC IEA Danio rerio 28879 R-DRE-977363 https://reactome.org/PathwayBrowser/#/R-DRE-977363 Factor H binds to C3bBb IEA Danio rerio 28879 R-DRE-981728 https://reactome.org/PathwayBrowser/#/R-DRE-981728 Factor H binds to membrane-associated C3b IEA Danio rerio 28879 R-GGA-1006169 https://reactome.org/PathwayBrowser/#/R-GGA-1006169 Factor H binds host cell surface markers IEA Gallus gallus 28879 R-GGA-166726 https://reactome.org/PathwayBrowser/#/R-GGA-166726 Activation of MASPs IEA Gallus gallus 28879 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus 28879 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus 28879 R-GGA-2855125 https://reactome.org/PathwayBrowser/#/R-GGA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Gallus gallus 28879 R-GGA-977363 https://reactome.org/PathwayBrowser/#/R-GGA-977363 Factor H binds to C3bBb IEA Gallus gallus 28879 R-GGA-981728 https://reactome.org/PathwayBrowser/#/R-GGA-981728 Factor H binds to membrane-associated C3b IEA Gallus gallus 28879 R-HSA-1006169 https://reactome.org/PathwayBrowser/#/R-HSA-1006169 Factor H binds host cell surface markers TAS Homo sapiens 28879 R-HSA-166726 https://reactome.org/PathwayBrowser/#/R-HSA-166726 Activation of MASPs TAS Homo sapiens 28879 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens 28879 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens 28879 R-HSA-2855125 https://reactome.org/PathwayBrowser/#/R-HSA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface TAS Homo sapiens 28879 R-HSA-422454 https://reactome.org/PathwayBrowser/#/R-HSA-422454 Polysialylation of NCAM1 TAS Homo sapiens 28879 R-HSA-5685607 https://reactome.org/PathwayBrowser/#/R-HSA-5685607 Sialic acid binds SIGLEC TAS Homo sapiens 28879 R-HSA-977363 https://reactome.org/PathwayBrowser/#/R-HSA-977363 Factor H binds to C3bBb TAS Homo sapiens 28879 R-HSA-981728 https://reactome.org/PathwayBrowser/#/R-HSA-981728 Factor H binds to membrane-associated C3b TAS Homo sapiens 28879 R-MMU-166726 https://reactome.org/PathwayBrowser/#/R-MMU-166726 Activation of MASPs IEA Mus musculus 28879 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus 28879 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus 28879 R-MMU-2855125 https://reactome.org/PathwayBrowser/#/R-MMU-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Mus musculus 28879 R-MMU-422454 https://reactome.org/PathwayBrowser/#/R-MMU-422454 Polysialylation of NCAM1 IEA Mus musculus 28879 R-MMU-5685607 https://reactome.org/PathwayBrowser/#/R-MMU-5685607 Sialic acid binds SIGLEC IEA Mus musculus 28879 R-RNO-166726 https://reactome.org/PathwayBrowser/#/R-RNO-166726 Activation of MASPs IEA Rattus norvegicus 28879 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus 28879 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus 28879 R-RNO-2855125 https://reactome.org/PathwayBrowser/#/R-RNO-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Rattus norvegicus 28879 R-RNO-422454 https://reactome.org/PathwayBrowser/#/R-RNO-422454 Polysialylation of NCAM1 IEA Rattus norvegicus 28879 R-RNO-5685607 https://reactome.org/PathwayBrowser/#/R-RNO-5685607 Sialic acid binds SIGLEC IEA Rattus norvegicus 28879 R-SSC-1006169 https://reactome.org/PathwayBrowser/#/R-SSC-1006169 Factor H binds host cell surface markers IEA Sus scrofa 28879 R-SSC-166726 https://reactome.org/PathwayBrowser/#/R-SSC-166726 Activation of MASPs IEA Sus scrofa 28879 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa 28879 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa 28879 R-SSC-2855125 https://reactome.org/PathwayBrowser/#/R-SSC-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Sus scrofa 28879 R-SSC-5685607 https://reactome.org/PathwayBrowser/#/R-SSC-5685607 Sialic acid binds SIGLEC IEA Sus scrofa 28879 R-SSC-977363 https://reactome.org/PathwayBrowser/#/R-SSC-977363 Factor H binds to C3bBb IEA Sus scrofa 28879 R-SSC-981728 https://reactome.org/PathwayBrowser/#/R-SSC-981728 Factor H binds to membrane-associated C3b IEA Sus scrofa 28879 R-XTR-1006169 https://reactome.org/PathwayBrowser/#/R-XTR-1006169 Factor H binds host cell surface markers IEA Xenopus tropicalis 28879 R-XTR-166726 https://reactome.org/PathwayBrowser/#/R-XTR-166726 Activation of MASPs IEA Xenopus tropicalis 28879 R-XTR-166753 https://reactome.org/PathwayBrowser/#/R-XTR-166753 Conversion of C4 into C4a and C4b IEA Xenopus tropicalis 28879 R-XTR-166792 https://reactome.org/PathwayBrowser/#/R-XTR-166792 Conversion of C2 into C2a and C2b IEA Xenopus tropicalis 28879 R-XTR-2855125 https://reactome.org/PathwayBrowser/#/R-XTR-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Xenopus tropicalis 28879 R-XTR-5685607 https://reactome.org/PathwayBrowser/#/R-XTR-5685607 Sialic acid binds SIGLEC IEA Xenopus tropicalis 28879 R-XTR-977363 https://reactome.org/PathwayBrowser/#/R-XTR-977363 Factor H binds to C3bBb IEA Xenopus tropicalis 28879 R-XTR-981728 https://reactome.org/PathwayBrowser/#/R-XTR-981728 Factor H binds to membrane-associated C3b IEA Xenopus tropicalis 28881 R-BTA-6799977 https://reactome.org/PathwayBrowser/#/R-BTA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Bos taurus 28881 R-CFA-6799977 https://reactome.org/PathwayBrowser/#/R-CFA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Canis familiaris 28881 R-DME-209158 https://reactome.org/PathwayBrowser/#/R-DME-209158 Polymeric PGN bound PGRP-LCx multimerises at the plasma membrane TAS Drosophila melanogaster 28881 R-DME-209167 https://reactome.org/PathwayBrowser/#/R-DME-209167 Phosphorylated REL is cleaved by and dissociates from DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' TAS Drosophila melanogaster 28881 R-DME-209221 https://reactome.org/PathwayBrowser/#/R-DME-209221 Assembly of the PGN:PGRP-LC oligomer receptor 'signalling complex' IEA Drosophila melanogaster 28881 R-DME-209227 https://reactome.org/PathwayBrowser/#/R-DME-209227 Activated Phospho IRD5:KEY dimer phosphorylates REL in the PGN:PGRP-LC oligomer receptor 'signalling complex' TAS Drosophila melanogaster 28881 R-DME-209244 https://reactome.org/PathwayBrowser/#/R-DME-209244 REL binds to DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' TAS Drosophila melanogaster 28881 R-DME-209377 https://reactome.org/PathwayBrowser/#/R-DME-209377 Polymeric PGN binds to PGRP-LCx at the plasma membrane TAS Drosophila melanogaster 28881 R-DME-6799977 https://reactome.org/PathwayBrowser/#/R-DME-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Drosophila melanogaster 28881 R-DRE-6799977 https://reactome.org/PathwayBrowser/#/R-DRE-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Danio rerio 28881 R-GGA-6799977 https://reactome.org/PathwayBrowser/#/R-GGA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Gallus gallus 28881 R-HSA-6799977 https://reactome.org/PathwayBrowser/#/R-HSA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan TAS Homo sapiens 28881 R-MMU-6799977 https://reactome.org/PathwayBrowser/#/R-MMU-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Mus musculus 28881 R-RNO-6799977 https://reactome.org/PathwayBrowser/#/R-RNO-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Rattus norvegicus 28881 R-SSC-6799977 https://reactome.org/PathwayBrowser/#/R-SSC-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Sus scrofa 28881 R-XTR-6799977 https://reactome.org/PathwayBrowser/#/R-XTR-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Xenopus tropicalis 28895 R-HSA-9705961 https://reactome.org/PathwayBrowser/#/R-HSA-9705961 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 28895 R-HSA-9755252 https://reactome.org/PathwayBrowser/#/R-HSA-9755252 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 28911 R-HSA-3299657 https://reactome.org/PathwayBrowser/#/R-HSA-3299657 Defective TCII does not bind Cbl in the circulation TAS Homo sapiens 28911 R-HSA-3315455 https://reactome.org/PathwayBrowser/#/R-HSA-3315455 Defective CBLIF does not bind Cbl TAS Homo sapiens 28911 R-HSA-3318576 https://reactome.org/PathwayBrowser/#/R-HSA-3318576 Defective MMACHC does not reduce Cbl TAS Homo sapiens 28911 R-HSA-3325546 https://reactome.org/PathwayBrowser/#/R-HSA-3325546 Defective CD320 does not transport extracellular TCII:Cbl to endosome TAS Homo sapiens 28911 R-HSA-5683325 https://reactome.org/PathwayBrowser/#/R-HSA-5683325 Defective ABCD4:LMBRD1 does not transport Cbl from lysosomal lumen to cytosol TAS Homo sapiens 28912 R-BTA-189053 https://reactome.org/PathwayBrowser/#/R-BTA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Bos taurus 28912 R-BTA-191114 https://reactome.org/PathwayBrowser/#/R-BTA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Bos taurus 28912 R-CEL-189053 https://reactome.org/PathwayBrowser/#/R-CEL-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Caenorhabditis elegans 28912 R-CEL-191114 https://reactome.org/PathwayBrowser/#/R-CEL-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Caenorhabditis elegans 28912 R-CFA-189053 https://reactome.org/PathwayBrowser/#/R-CFA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Canis familiaris 28912 R-CFA-191114 https://reactome.org/PathwayBrowser/#/R-CFA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Canis familiaris 28912 R-DDI-189053 https://reactome.org/PathwayBrowser/#/R-DDI-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Dictyostelium discoideum 28912 R-DME-191114 https://reactome.org/PathwayBrowser/#/R-DME-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Drosophila melanogaster 28912 R-DRE-191114 https://reactome.org/PathwayBrowser/#/R-DRE-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Danio rerio 28912 R-GGA-189053 https://reactome.org/PathwayBrowser/#/R-GGA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Gallus gallus 28912 R-GGA-191114 https://reactome.org/PathwayBrowser/#/R-GGA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Gallus gallus 28912 R-HSA-189053 https://reactome.org/PathwayBrowser/#/R-HSA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose TAS Homo sapiens 28912 R-HSA-191114 https://reactome.org/PathwayBrowser/#/R-HSA-191114 Digestion of branched starch (amylopectin) by extracellular amylase TAS Homo sapiens 28912 R-MMU-189053 https://reactome.org/PathwayBrowser/#/R-MMU-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Mus musculus 28912 R-MMU-191114 https://reactome.org/PathwayBrowser/#/R-MMU-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Mus musculus 28912 R-RNO-189053 https://reactome.org/PathwayBrowser/#/R-RNO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Rattus norvegicus 28912 R-RNO-191114 https://reactome.org/PathwayBrowser/#/R-RNO-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Rattus norvegicus 28912 R-SPO-189053 https://reactome.org/PathwayBrowser/#/R-SPO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Schizosaccharomyces pombe 28912 R-SSC-189053 https://reactome.org/PathwayBrowser/#/R-SSC-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Sus scrofa 28912 R-SSC-191114 https://reactome.org/PathwayBrowser/#/R-SSC-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Sus scrofa 28912 R-XTR-191114 https://reactome.org/PathwayBrowser/#/R-XTR-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Xenopus tropicalis 28914 R-BTA-1482598 https://reactome.org/PathwayBrowser/#/R-BTA-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Bos taurus 28914 R-BTA-1482825 https://reactome.org/PathwayBrowser/#/R-BTA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Bos taurus 28914 R-BTA-1482868 https://reactome.org/PathwayBrowser/#/R-BTA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Bos taurus 28914 R-BTA-1602377 https://reactome.org/PathwayBrowser/#/R-BTA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Bos taurus 28914 R-CEL-1482598 https://reactome.org/PathwayBrowser/#/R-CEL-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Caenorhabditis elegans 28914 R-CEL-1482868 https://reactome.org/PathwayBrowser/#/R-CEL-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Caenorhabditis elegans 28914 R-CEL-1602377 https://reactome.org/PathwayBrowser/#/R-CEL-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Caenorhabditis elegans 28914 R-CFA-1482598 https://reactome.org/PathwayBrowser/#/R-CFA-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Canis familiaris 28914 R-CFA-1482825 https://reactome.org/PathwayBrowser/#/R-CFA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Canis familiaris 28914 R-CFA-1602377 https://reactome.org/PathwayBrowser/#/R-CFA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Canis familiaris 28914 R-DDI-1482598 https://reactome.org/PathwayBrowser/#/R-DDI-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Dictyostelium discoideum 28914 R-DDI-1482825 https://reactome.org/PathwayBrowser/#/R-DDI-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Dictyostelium discoideum 28914 R-DME-1482598 https://reactome.org/PathwayBrowser/#/R-DME-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Drosophila melanogaster 28914 R-DME-1482868 https://reactome.org/PathwayBrowser/#/R-DME-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Drosophila melanogaster 28914 R-DME-1602377 https://reactome.org/PathwayBrowser/#/R-DME-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Drosophila melanogaster 28914 R-DRE-1482598 https://reactome.org/PathwayBrowser/#/R-DRE-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Danio rerio 28914 R-DRE-1482825 https://reactome.org/PathwayBrowser/#/R-DRE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Danio rerio 28914 R-DRE-1482868 https://reactome.org/PathwayBrowser/#/R-DRE-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Danio rerio 28914 R-DRE-1602377 https://reactome.org/PathwayBrowser/#/R-DRE-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Danio rerio 28914 R-GGA-1482825 https://reactome.org/PathwayBrowser/#/R-GGA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Gallus gallus 28914 R-GGA-1482868 https://reactome.org/PathwayBrowser/#/R-GGA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Gallus gallus 28914 R-GGA-1602377 https://reactome.org/PathwayBrowser/#/R-GGA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Gallus gallus 28914 R-HSA-1482598 https://reactome.org/PathwayBrowser/#/R-HSA-1482598 1-acyl LPI is acylated to PI by MBOAT7 TAS Homo sapiens 28914 R-HSA-1482825 https://reactome.org/PathwayBrowser/#/R-HSA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] TAS Homo sapiens 28914 R-HSA-1482868 https://reactome.org/PathwayBrowser/#/R-HSA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] TAS Homo sapiens 28914 R-HSA-1602377 https://reactome.org/PathwayBrowser/#/R-HSA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] TAS Homo sapiens 28914 R-MMU-1482598 https://reactome.org/PathwayBrowser/#/R-MMU-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Mus musculus 28914 R-MMU-1482825 https://reactome.org/PathwayBrowser/#/R-MMU-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Mus musculus 28914 R-MMU-1482868 https://reactome.org/PathwayBrowser/#/R-MMU-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Mus musculus 28914 R-MMU-1602377 https://reactome.org/PathwayBrowser/#/R-MMU-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Mus musculus 28914 R-RNO-1482825 https://reactome.org/PathwayBrowser/#/R-RNO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Rattus norvegicus 28914 R-RNO-1482868 https://reactome.org/PathwayBrowser/#/R-RNO-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Rattus norvegicus 28914 R-RNO-1602377 https://reactome.org/PathwayBrowser/#/R-RNO-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Rattus norvegicus 28914 R-SCE-1482598 https://reactome.org/PathwayBrowser/#/R-SCE-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Saccharomyces cerevisiae 28914 R-SCE-1482825 https://reactome.org/PathwayBrowser/#/R-SCE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Saccharomyces cerevisiae 28914 R-SCE-1482868 https://reactome.org/PathwayBrowser/#/R-SCE-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Saccharomyces cerevisiae 28914 R-SPO-1482598 https://reactome.org/PathwayBrowser/#/R-SPO-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Schizosaccharomyces pombe 28914 R-SPO-1482825 https://reactome.org/PathwayBrowser/#/R-SPO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Schizosaccharomyces pombe 28914 R-SPO-1482868 https://reactome.org/PathwayBrowser/#/R-SPO-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Schizosaccharomyces pombe 28914 R-SSC-1482598 https://reactome.org/PathwayBrowser/#/R-SSC-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Sus scrofa 28914 R-SSC-1482825 https://reactome.org/PathwayBrowser/#/R-SSC-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Sus scrofa 28914 R-SSC-1482868 https://reactome.org/PathwayBrowser/#/R-SSC-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Sus scrofa 28914 R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa 28914 R-XTR-1482598 https://reactome.org/PathwayBrowser/#/R-XTR-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Xenopus tropicalis 28914 R-XTR-1482825 https://reactome.org/PathwayBrowser/#/R-XTR-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Xenopus tropicalis 28914 R-XTR-1482868 https://reactome.org/PathwayBrowser/#/R-XTR-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Xenopus tropicalis 28914 R-XTR-1602377 https://reactome.org/PathwayBrowser/#/R-XTR-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Xenopus tropicalis 28936 R-BTA-1482646 https://reactome.org/PathwayBrowser/#/R-BTA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Bos taurus 28936 R-BTA-1482828 https://reactome.org/PathwayBrowser/#/R-BTA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Bos taurus 28936 R-CEL-1482646 https://reactome.org/PathwayBrowser/#/R-CEL-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Caenorhabditis elegans 28936 R-CFA-1482646 https://reactome.org/PathwayBrowser/#/R-CFA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Canis familiaris 28936 R-CFA-1482828 https://reactome.org/PathwayBrowser/#/R-CFA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Canis familiaris 28936 R-DDI-1482646 https://reactome.org/PathwayBrowser/#/R-DDI-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Dictyostelium discoideum 28936 R-DME-1482646 https://reactome.org/PathwayBrowser/#/R-DME-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Drosophila melanogaster 28936 R-DRE-1482545 https://reactome.org/PathwayBrowser/#/R-DRE-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Danio rerio 28936 R-DRE-1482828 https://reactome.org/PathwayBrowser/#/R-DRE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Danio rerio 28936 R-DRE-1482892 https://reactome.org/PathwayBrowser/#/R-DRE-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Danio rerio 28936 R-GGA-1482646 https://reactome.org/PathwayBrowser/#/R-GGA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Gallus gallus 28936 R-GGA-1482828 https://reactome.org/PathwayBrowser/#/R-GGA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Gallus gallus 28936 R-HSA-1482545 https://reactome.org/PathwayBrowser/#/R-HSA-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C TAS Homo sapiens 28936 R-HSA-1482646 https://reactome.org/PathwayBrowser/#/R-HSA-1482646 2-acyl LPE is acylated to PE by LPEAT TAS Homo sapiens 28936 R-HSA-1482828 https://reactome.org/PathwayBrowser/#/R-HSA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] TAS Homo sapiens 28936 R-HSA-1482892 https://reactome.org/PathwayBrowser/#/R-HSA-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C TAS Homo sapiens 28936 R-MMU-1482545 https://reactome.org/PathwayBrowser/#/R-MMU-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Mus musculus 28936 R-MMU-1482646 https://reactome.org/PathwayBrowser/#/R-MMU-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Mus musculus 28936 R-MMU-1482828 https://reactome.org/PathwayBrowser/#/R-MMU-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Mus musculus 28936 R-MMU-1482892 https://reactome.org/PathwayBrowser/#/R-MMU-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Mus musculus 28936 R-PFA-1482646 https://reactome.org/PathwayBrowser/#/R-PFA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Plasmodium falciparum 28936 R-RNO-1482545 https://reactome.org/PathwayBrowser/#/R-RNO-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Rattus norvegicus 28936 R-RNO-1482646 https://reactome.org/PathwayBrowser/#/R-RNO-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Rattus norvegicus 28936 R-RNO-1482828 https://reactome.org/PathwayBrowser/#/R-RNO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Rattus norvegicus 28936 R-RNO-1482892 https://reactome.org/PathwayBrowser/#/R-RNO-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Rattus norvegicus 28936 R-SCE-1482545 https://reactome.org/PathwayBrowser/#/R-SCE-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Saccharomyces cerevisiae 28936 R-SCE-1482646 https://reactome.org/PathwayBrowser/#/R-SCE-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Saccharomyces cerevisiae 28936 R-SCE-1482828 https://reactome.org/PathwayBrowser/#/R-SCE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Saccharomyces cerevisiae 28936 R-SCE-1482892 https://reactome.org/PathwayBrowser/#/R-SCE-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Saccharomyces cerevisiae 28936 R-SPO-1482545 https://reactome.org/PathwayBrowser/#/R-SPO-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Schizosaccharomyces pombe 28936 R-SPO-1482646 https://reactome.org/PathwayBrowser/#/R-SPO-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Schizosaccharomyces pombe 28936 R-SPO-1482828 https://reactome.org/PathwayBrowser/#/R-SPO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Schizosaccharomyces pombe 28936 R-SPO-1482892 https://reactome.org/PathwayBrowser/#/R-SPO-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Schizosaccharomyces pombe 28936 R-SSC-1482646 https://reactome.org/PathwayBrowser/#/R-SSC-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Sus scrofa 28936 R-SSC-1482828 https://reactome.org/PathwayBrowser/#/R-SSC-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Sus scrofa 28936 R-XTR-1482646 https://reactome.org/PathwayBrowser/#/R-XTR-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Xenopus tropicalis 28936 R-XTR-1482828 https://reactome.org/PathwayBrowser/#/R-XTR-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Xenopus tropicalis 28938 R-BTA-141186 https://reactome.org/PathwayBrowser/#/R-BTA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Bos taurus 28938 R-BTA-189406 https://reactome.org/PathwayBrowser/#/R-BTA-189406 4 PBGs bind to form HMB IEA Bos taurus 28938 R-BTA-389821 https://reactome.org/PathwayBrowser/#/R-BTA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Bos taurus 28938 R-BTA-444393 https://reactome.org/PathwayBrowser/#/R-BTA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Bos taurus 28938 R-BTA-444416 https://reactome.org/PathwayBrowser/#/R-BTA-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) IEA Bos taurus 28938 R-BTA-444419 https://reactome.org/PathwayBrowser/#/R-BTA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Bos taurus 28938 R-BTA-446277 https://reactome.org/PathwayBrowser/#/R-BTA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Bos taurus 28938 R-BTA-446278 https://reactome.org/PathwayBrowser/#/R-BTA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Bos taurus 28938 R-BTA-514604 https://reactome.org/PathwayBrowser/#/R-BTA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Bos taurus 28938 R-BTA-5358475 https://reactome.org/PathwayBrowser/#/R-BTA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Bos taurus 28938 R-BTA-6799604 https://reactome.org/PathwayBrowser/#/R-BTA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Bos taurus 28938 R-BTA-6810076 https://reactome.org/PathwayBrowser/#/R-BTA-6810076 DDO oxidizes D-Asp to OA IEA Bos taurus 28938 R-BTA-70555 https://reactome.org/PathwayBrowser/#/R-BTA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Bos taurus 28938 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Bos taurus 28938 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Bos taurus 28938 R-BTA-70606 https://reactome.org/PathwayBrowser/#/R-BTA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Bos taurus 28938 R-BTA-70609 https://reactome.org/PathwayBrowser/#/R-BTA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Bos taurus 28938 R-BTA-70899 https://reactome.org/PathwayBrowser/#/R-BTA-70899 histidine => urocanate + NH4+ IEA Bos taurus 28938 R-BTA-73591 https://reactome.org/PathwayBrowser/#/R-BTA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Bos taurus 28938 R-BTA-73596 https://reactome.org/PathwayBrowser/#/R-BTA-73596 dCMP + H2O => dUMP + NH4+ IEA Bos taurus 28938 R-BTA-73608 https://reactome.org/PathwayBrowser/#/R-BTA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Bos taurus 28938 R-BTA-73620 https://reactome.org/PathwayBrowser/#/R-BTA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Bos taurus 28938 R-BTA-74241 https://reactome.org/PathwayBrowser/#/R-BTA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Bos taurus 28938 R-BTA-74255 https://reactome.org/PathwayBrowser/#/R-BTA-74255 Guanine + H2O => Xanthine + NH4+ IEA Bos taurus 28938 R-BTA-76590 https://reactome.org/PathwayBrowser/#/R-BTA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Bos taurus 28938 R-BTA-965079 https://reactome.org/PathwayBrowser/#/R-BTA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Bos taurus 28938 R-BTA-9754964 https://reactome.org/PathwayBrowser/#/R-BTA-9754964 ADA deamidates RBV IEA Bos taurus 28938 R-CEL-389821 https://reactome.org/PathwayBrowser/#/R-CEL-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Caenorhabditis elegans 28938 R-CEL-444393 https://reactome.org/PathwayBrowser/#/R-CEL-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Caenorhabditis elegans 28938 R-CEL-444416 https://reactome.org/PathwayBrowser/#/R-CEL-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) IEA Caenorhabditis elegans 28938 R-CEL-444419 https://reactome.org/PathwayBrowser/#/R-CEL-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Caenorhabditis elegans 28938 R-CEL-446277 https://reactome.org/PathwayBrowser/#/R-CEL-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Caenorhabditis elegans 28938 R-CEL-446278 https://reactome.org/PathwayBrowser/#/R-CEL-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Caenorhabditis elegans 28938 R-CEL-514604 https://reactome.org/PathwayBrowser/#/R-CEL-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Caenorhabditis elegans 28938 R-CEL-5358475 https://reactome.org/PathwayBrowser/#/R-CEL-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Caenorhabditis elegans 28938 R-CEL-6799604 https://reactome.org/PathwayBrowser/#/R-CEL-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Caenorhabditis elegans 28938 R-CEL-6810076 https://reactome.org/PathwayBrowser/#/R-CEL-6810076 DDO oxidizes D-Asp to OA IEA Caenorhabditis elegans 28938 R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Caenorhabditis elegans 28938 R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Caenorhabditis elegans 28938 R-CEL-70606 https://reactome.org/PathwayBrowser/#/R-CEL-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Caenorhabditis elegans 28938 R-CEL-70609 https://reactome.org/PathwayBrowser/#/R-CEL-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Caenorhabditis elegans 28938 R-CEL-70899 https://reactome.org/PathwayBrowser/#/R-CEL-70899 histidine => urocanate + NH4+ IEA Caenorhabditis elegans 28938 R-CEL-73591 https://reactome.org/PathwayBrowser/#/R-CEL-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Caenorhabditis elegans 28938 R-CEL-73608 https://reactome.org/PathwayBrowser/#/R-CEL-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Caenorhabditis elegans 28938 R-CEL-73620 https://reactome.org/PathwayBrowser/#/R-CEL-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Caenorhabditis elegans 28938 R-CEL-74241 https://reactome.org/PathwayBrowser/#/R-CEL-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Caenorhabditis elegans 28938 R-CEL-76590 https://reactome.org/PathwayBrowser/#/R-CEL-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Caenorhabditis elegans 28938 R-CEL-965079 https://reactome.org/PathwayBrowser/#/R-CEL-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Caenorhabditis elegans 28938 R-CEL-9754964 https://reactome.org/PathwayBrowser/#/R-CEL-9754964 ADA deamidates RBV IEA Caenorhabditis elegans 28938 R-CFA-141186 https://reactome.org/PathwayBrowser/#/R-CFA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Canis familiaris 28938 R-CFA-189406 https://reactome.org/PathwayBrowser/#/R-CFA-189406 4 PBGs bind to form HMB IEA Canis familiaris 28938 R-CFA-389821 https://reactome.org/PathwayBrowser/#/R-CFA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Canis familiaris 28938 R-CFA-444393 https://reactome.org/PathwayBrowser/#/R-CFA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Canis familiaris 28938 R-CFA-444416 https://reactome.org/PathwayBrowser/#/R-CFA-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) IEA Canis familiaris 28938 R-CFA-444419 https://reactome.org/PathwayBrowser/#/R-CFA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Canis familiaris 28938 R-CFA-446277 https://reactome.org/PathwayBrowser/#/R-CFA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Canis familiaris 28938 R-CFA-446278 https://reactome.org/PathwayBrowser/#/R-CFA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Canis familiaris 28938 R-CFA-514604 https://reactome.org/PathwayBrowser/#/R-CFA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Canis familiaris 28938 R-CFA-5358475 https://reactome.org/PathwayBrowser/#/R-CFA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Canis familiaris 28938 R-CFA-6799604 https://reactome.org/PathwayBrowser/#/R-CFA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Canis familiaris 28938 R-CFA-6810076 https://reactome.org/PathwayBrowser/#/R-CFA-6810076 DDO oxidizes D-Asp to OA IEA Canis familiaris 28938 R-CFA-70555 https://reactome.org/PathwayBrowser/#/R-CFA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Canis familiaris 28938 R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Canis familiaris 28938 R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Canis familiaris 28938 R-CFA-70606 https://reactome.org/PathwayBrowser/#/R-CFA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Canis familiaris 28938 R-CFA-70609 https://reactome.org/PathwayBrowser/#/R-CFA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Canis familiaris 28938 R-CFA-70899 https://reactome.org/PathwayBrowser/#/R-CFA-70899 histidine => urocanate + NH4+ IEA Canis familiaris 28938 R-CFA-73591 https://reactome.org/PathwayBrowser/#/R-CFA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Canis familiaris 28938 R-CFA-73596 https://reactome.org/PathwayBrowser/#/R-CFA-73596 dCMP + H2O => dUMP + NH4+ IEA Canis familiaris 28938 R-CFA-73608 https://reactome.org/PathwayBrowser/#/R-CFA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Canis familiaris 28938 R-CFA-73620 https://reactome.org/PathwayBrowser/#/R-CFA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Canis familiaris 28938 R-CFA-74241 https://reactome.org/PathwayBrowser/#/R-CFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Canis familiaris 28938 R-CFA-74255 https://reactome.org/PathwayBrowser/#/R-CFA-74255 Guanine + H2O => Xanthine + NH4+ IEA Canis familiaris 28938 R-CFA-76590 https://reactome.org/PathwayBrowser/#/R-CFA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Canis familiaris 28938 R-CFA-965079 https://reactome.org/PathwayBrowser/#/R-CFA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Canis familiaris 28938 R-CFA-9754964 https://reactome.org/PathwayBrowser/#/R-CFA-9754964 ADA deamidates RBV IEA Canis familiaris 28938 R-DDI-141186 https://reactome.org/PathwayBrowser/#/R-DDI-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Dictyostelium discoideum 28938 R-DDI-389821 https://reactome.org/PathwayBrowser/#/R-DDI-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Dictyostelium discoideum 28938 R-DDI-444393 https://reactome.org/PathwayBrowser/#/R-DDI-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Dictyostelium discoideum 28938 R-DDI-444416 https://reactome.org/PathwayBrowser/#/R-DDI-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) IEA Dictyostelium discoideum 28938 R-DDI-444419 https://reactome.org/PathwayBrowser/#/R-DDI-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Dictyostelium discoideum 28938 R-DDI-446277 https://reactome.org/PathwayBrowser/#/R-DDI-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Dictyostelium discoideum 28938 R-DDI-446278 https://reactome.org/PathwayBrowser/#/R-DDI-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Dictyostelium discoideum 28938 R-DDI-5358475 https://reactome.org/PathwayBrowser/#/R-DDI-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Dictyostelium discoideum 28938 R-DDI-6799604 https://reactome.org/PathwayBrowser/#/R-DDI-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Dictyostelium discoideum 28938 R-DDI-6810076 https://reactome.org/PathwayBrowser/#/R-DDI-6810076 DDO oxidizes D-Asp to OA IEA Dictyostelium discoideum 28938 R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Dictyostelium discoideum 28938 R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Dictyostelium discoideum 28938 R-DDI-70899 https://reactome.org/PathwayBrowser/#/R-DDI-70899 histidine => urocanate + NH4+ IEA Dictyostelium discoideum 28938 R-DDI-73591 https://reactome.org/PathwayBrowser/#/R-DDI-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Dictyostelium discoideum 28938 R-DDI-73608 https://reactome.org/PathwayBrowser/#/R-DDI-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Dictyostelium discoideum 28938 R-DDI-73620 https://reactome.org/PathwayBrowser/#/R-DDI-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Dictyostelium discoideum 28938 R-DDI-74241 https://reactome.org/PathwayBrowser/#/R-DDI-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Dictyostelium discoideum 28938 R-DDI-74255 https://reactome.org/PathwayBrowser/#/R-DDI-74255 Guanine + H2O => Xanthine + NH4+ IEA Dictyostelium discoideum 28938 R-DDI-76590 https://reactome.org/PathwayBrowser/#/R-DDI-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Dictyostelium discoideum 28938 R-DDI-965079 https://reactome.org/PathwayBrowser/#/R-DDI-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Dictyostelium discoideum 28938 R-DDI-9754964 https://reactome.org/PathwayBrowser/#/R-DDI-9754964 ADA deamidates RBV IEA Dictyostelium discoideum 28938 R-DME-189406 https://reactome.org/PathwayBrowser/#/R-DME-189406 4 PBGs bind to form HMB IEA Drosophila melanogaster 28938 R-DME-389821 https://reactome.org/PathwayBrowser/#/R-DME-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Drosophila melanogaster 28938 R-DME-444393 https://reactome.org/PathwayBrowser/#/R-DME-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Drosophila melanogaster 28938 R-DME-444416 https://reactome.org/PathwayBrowser/#/R-DME-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) IEA Drosophila melanogaster 28938 R-DME-444419 https://reactome.org/PathwayBrowser/#/R-DME-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Drosophila melanogaster 28938 R-DME-446277 https://reactome.org/PathwayBrowser/#/R-DME-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Drosophila melanogaster 28938 R-DME-446278 https://reactome.org/PathwayBrowser/#/R-DME-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Drosophila melanogaster 28938 R-DME-5358475 https://reactome.org/PathwayBrowser/#/R-DME-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Drosophila melanogaster 28938 R-DME-6799604 https://reactome.org/PathwayBrowser/#/R-DME-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Drosophila melanogaster 28938 R-DME-6810076 https://reactome.org/PathwayBrowser/#/R-DME-6810076 DDO oxidizes D-Asp to OA IEA Drosophila melanogaster 28938 R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Drosophila melanogaster 28938 R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Drosophila melanogaster 28938 R-DME-70606 https://reactome.org/PathwayBrowser/#/R-DME-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Drosophila melanogaster 28938 R-DME-70609 https://reactome.org/PathwayBrowser/#/R-DME-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Drosophila melanogaster 28938 R-DME-73591 https://reactome.org/PathwayBrowser/#/R-DME-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Drosophila melanogaster 28938 R-DME-73608 https://reactome.org/PathwayBrowser/#/R-DME-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Drosophila melanogaster 28938 R-DME-73620 https://reactome.org/PathwayBrowser/#/R-DME-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Drosophila melanogaster 28938 R-DME-74255 https://reactome.org/PathwayBrowser/#/R-DME-74255 Guanine + H2O => Xanthine + NH4+ IEA Drosophila melanogaster 28938 R-DME-76590 https://reactome.org/PathwayBrowser/#/R-DME-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Drosophila melanogaster 28938 R-DME-965079 https://reactome.org/PathwayBrowser/#/R-DME-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Drosophila melanogaster 28938 R-DRE-389821 https://reactome.org/PathwayBrowser/#/R-DRE-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Danio rerio 28938 R-DRE-444393 https://reactome.org/PathwayBrowser/#/R-DRE-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Danio rerio 28938 R-DRE-444416 https://reactome.org/PathwayBrowser/#/R-DRE-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) IEA Danio rerio 28938 R-DRE-444419 https://reactome.org/PathwayBrowser/#/R-DRE-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Danio rerio 28938 R-DRE-446277 https://reactome.org/PathwayBrowser/#/R-DRE-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Danio rerio 28938 R-DRE-446278 https://reactome.org/PathwayBrowser/#/R-DRE-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Danio rerio 28938 R-DRE-514604 https://reactome.org/PathwayBrowser/#/R-DRE-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Danio rerio 28938 R-DRE-6799604 https://reactome.org/PathwayBrowser/#/R-DRE-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Danio rerio 28938 R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Danio rerio 28938 R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Danio rerio 28938 R-DRE-70606 https://reactome.org/PathwayBrowser/#/R-DRE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Danio rerio 28938 R-DRE-70609 https://reactome.org/PathwayBrowser/#/R-DRE-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Danio rerio 28938 R-DRE-70899 https://reactome.org/PathwayBrowser/#/R-DRE-70899 histidine => urocanate + NH4+ IEA Danio rerio 28938 R-DRE-73591 https://reactome.org/PathwayBrowser/#/R-DRE-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Danio rerio 28938 R-DRE-73596 https://reactome.org/PathwayBrowser/#/R-DRE-73596 dCMP + H2O => dUMP + NH4+ IEA Danio rerio 28938 R-DRE-73608 https://reactome.org/PathwayBrowser/#/R-DRE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Danio rerio 28938 R-DRE-73620 https://reactome.org/PathwayBrowser/#/R-DRE-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Danio rerio 28938 R-DRE-74241 https://reactome.org/PathwayBrowser/#/R-DRE-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Danio rerio 28938 R-DRE-74255 https://reactome.org/PathwayBrowser/#/R-DRE-74255 Guanine + H2O => Xanthine + NH4+ IEA Danio rerio 28938 R-DRE-76590 https://reactome.org/PathwayBrowser/#/R-DRE-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Danio rerio 28938 R-DRE-9754964 https://reactome.org/PathwayBrowser/#/R-DRE-9754964 ADA deamidates RBV IEA Danio rerio 28938 R-GGA-140851 https://reactome.org/PathwayBrowser/#/R-GGA-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Gallus gallus 28938 R-GGA-141186 https://reactome.org/PathwayBrowser/#/R-GGA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Gallus gallus 28938 R-GGA-189406 https://reactome.org/PathwayBrowser/#/R-GGA-189406 4 PBGs bind to form HMB IEA Gallus gallus 28938 R-GGA-389821 https://reactome.org/PathwayBrowser/#/R-GGA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Gallus gallus 28938 R-GGA-444393 https://reactome.org/PathwayBrowser/#/R-GGA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Gallus gallus 28938 R-GGA-444416 https://reactome.org/PathwayBrowser/#/R-GGA-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) IEA Gallus gallus 28938 R-GGA-444419 https://reactome.org/PathwayBrowser/#/R-GGA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Gallus gallus 28938 R-GGA-446277 https://reactome.org/PathwayBrowser/#/R-GGA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Gallus gallus 28938 R-GGA-446278 https://reactome.org/PathwayBrowser/#/R-GGA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Gallus gallus 28938 R-GGA-514604 https://reactome.org/PathwayBrowser/#/R-GGA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Gallus gallus 28938 R-GGA-5358475 https://reactome.org/PathwayBrowser/#/R-GGA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Gallus gallus 28938 R-GGA-6799604 https://reactome.org/PathwayBrowser/#/R-GGA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Gallus gallus 28938 R-GGA-6810076 https://reactome.org/PathwayBrowser/#/R-GGA-6810076 DDO oxidizes D-Asp to OA IEA Gallus gallus 28938 R-GGA-70555 https://reactome.org/PathwayBrowser/#/R-GGA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Gallus gallus 28938 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Gallus gallus 28938 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Gallus gallus 28938 R-GGA-70606 https://reactome.org/PathwayBrowser/#/R-GGA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Gallus gallus 28938 R-GGA-70609 https://reactome.org/PathwayBrowser/#/R-GGA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Gallus gallus 28938 R-GGA-70899 https://reactome.org/PathwayBrowser/#/R-GGA-70899 histidine => urocanate + NH4+ IEA Gallus gallus 28938 R-GGA-73591 https://reactome.org/PathwayBrowser/#/R-GGA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Gallus gallus 28938 R-GGA-73596 https://reactome.org/PathwayBrowser/#/R-GGA-73596 dCMP + H2O => dUMP + NH4+ IEA Gallus gallus 28938 R-GGA-73608 https://reactome.org/PathwayBrowser/#/R-GGA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Gallus gallus 28938 R-GGA-73620 https://reactome.org/PathwayBrowser/#/R-GGA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Gallus gallus 28938 R-GGA-74241 https://reactome.org/PathwayBrowser/#/R-GGA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Gallus gallus 28938 R-GGA-74255 https://reactome.org/PathwayBrowser/#/R-GGA-74255 Guanine + H2O => Xanthine + NH4+ IEA Gallus gallus 28938 R-GGA-76590 https://reactome.org/PathwayBrowser/#/R-GGA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Gallus gallus 28938 R-GGA-965079 https://reactome.org/PathwayBrowser/#/R-GGA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Gallus gallus 28938 R-GGA-9754964 https://reactome.org/PathwayBrowser/#/R-GGA-9754964 ADA deamidates RBV IEA Gallus gallus 28938 R-HSA-140851 https://reactome.org/PathwayBrowser/#/R-HSA-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ TAS Homo sapiens 28938 R-HSA-141186 https://reactome.org/PathwayBrowser/#/R-HSA-141186 MAOA:FAD oxidatively deaminates of 5HT TAS Homo sapiens 28938 R-HSA-189406 https://reactome.org/PathwayBrowser/#/R-HSA-189406 4 PBGs bind to form HMB TAS Homo sapiens 28938 R-HSA-389821 https://reactome.org/PathwayBrowser/#/R-HSA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ TAS Homo sapiens 28938 R-HSA-444393 https://reactome.org/PathwayBrowser/#/R-HSA-444393 RhCG mediates ammonium influx into kidney collecting duct cells TAS Homo sapiens 28938 R-HSA-444416 https://reactome.org/PathwayBrowser/#/R-HSA-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) TAS Homo sapiens 28938 R-HSA-444419 https://reactome.org/PathwayBrowser/#/R-HSA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells TAS Homo sapiens 28938 R-HSA-446277 https://reactome.org/PathwayBrowser/#/R-HSA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells TAS Homo sapiens 28938 R-HSA-446278 https://reactome.org/PathwayBrowser/#/R-HSA-446278 RhBG mediates ammonium influx into kidney collecting duct cells TAS Homo sapiens 28938 R-HSA-514604 https://reactome.org/PathwayBrowser/#/R-HSA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) TAS Homo sapiens 28938 R-HSA-5358475 https://reactome.org/PathwayBrowser/#/R-HSA-5358475 DPH6 ligates ammonium to diphthine-EEF2 TAS Homo sapiens 28938 R-HSA-5623051 https://reactome.org/PathwayBrowser/#/R-HSA-5623051 Defective RHAG does not transport NH4+ from cytosol to extracellular region (rbc) TAS Homo sapiens 28938 R-HSA-6799604 https://reactome.org/PathwayBrowser/#/R-HSA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P TAS Homo sapiens 28938 R-HSA-6810076 https://reactome.org/PathwayBrowser/#/R-HSA-6810076 DDO oxidizes D-Asp to OA TAS Homo sapiens 28938 R-HSA-70555 https://reactome.org/PathwayBrowser/#/R-HSA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] TAS Homo sapiens 28938 R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] TAS Homo sapiens 28938 R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] TAS Homo sapiens 28938 R-HSA-70606 https://reactome.org/PathwayBrowser/#/R-HSA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] TAS Homo sapiens 28938 R-HSA-70609 https://reactome.org/PathwayBrowser/#/R-HSA-70609 glutamine + H2O => glutamate + NH4+ [GLS] TAS Homo sapiens 28938 R-HSA-70899 https://reactome.org/PathwayBrowser/#/R-HSA-70899 histidine => urocanate + NH4+ TAS Homo sapiens 28938 R-HSA-73591 https://reactome.org/PathwayBrowser/#/R-HSA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 TAS Homo sapiens 28938 R-HSA-73596 https://reactome.org/PathwayBrowser/#/R-HSA-73596 dCMP + H2O => dUMP + NH4+ TAS Homo sapiens 28938 R-HSA-73608 https://reactome.org/PathwayBrowser/#/R-HSA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) TAS Homo sapiens 28938 R-HSA-73620 https://reactome.org/PathwayBrowser/#/R-HSA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 TAS Homo sapiens 28938 R-HSA-74241 https://reactome.org/PathwayBrowser/#/R-HSA-74241 ADA catalyzes the deamination of (deoxy)adenosine TAS Homo sapiens 28938 R-HSA-74255 https://reactome.org/PathwayBrowser/#/R-HSA-74255 Guanine + H2O => Xanthine + NH4+ TAS Homo sapiens 28938 R-HSA-76590 https://reactome.org/PathwayBrowser/#/R-HSA-76590 AMP + H2O => IMP + NH4+ (AMPD) TAS Homo sapiens 28938 R-HSA-965079 https://reactome.org/PathwayBrowser/#/R-HSA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP TAS Homo sapiens 28938 R-HSA-9754964 https://reactome.org/PathwayBrowser/#/R-HSA-9754964 ADA deamidates RBV TAS Homo sapiens 28938 R-HSA-9817513 https://reactome.org/PathwayBrowser/#/R-HSA-9817513 AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine IEA Homo sapiens 28938 R-MMU-140851 https://reactome.org/PathwayBrowser/#/R-MMU-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Mus musculus 28938 R-MMU-141186 https://reactome.org/PathwayBrowser/#/R-MMU-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Mus musculus 28938 R-MMU-189406 https://reactome.org/PathwayBrowser/#/R-MMU-189406 4 PBGs bind to form HMB IEA Mus musculus 28938 R-MMU-389821 https://reactome.org/PathwayBrowser/#/R-MMU-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Mus musculus 28938 R-MMU-444393 https://reactome.org/PathwayBrowser/#/R-MMU-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Mus musculus 28938 R-MMU-444416 https://reactome.org/PathwayBrowser/#/R-MMU-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) IEA Mus musculus 28938 R-MMU-444419 https://reactome.org/PathwayBrowser/#/R-MMU-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Mus musculus 28938 R-MMU-446277 https://reactome.org/PathwayBrowser/#/R-MMU-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Mus musculus 28938 R-MMU-446278 https://reactome.org/PathwayBrowser/#/R-MMU-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Mus musculus 28938 R-MMU-514604 https://reactome.org/PathwayBrowser/#/R-MMU-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Mus musculus 28938 R-MMU-5358475 https://reactome.org/PathwayBrowser/#/R-MMU-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Mus musculus 28938 R-MMU-6799604 https://reactome.org/PathwayBrowser/#/R-MMU-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Mus musculus 28938 R-MMU-6810076 https://reactome.org/PathwayBrowser/#/R-MMU-6810076 DDO oxidizes D-Asp to OA IEA Mus musculus 28938 R-MMU-70555 https://reactome.org/PathwayBrowser/#/R-MMU-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Mus musculus 28938 R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Mus musculus 28938 R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Mus musculus 28938 R-MMU-70606 https://reactome.org/PathwayBrowser/#/R-MMU-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Mus musculus 28938 R-MMU-70609 https://reactome.org/PathwayBrowser/#/R-MMU-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Mus musculus 28938 R-MMU-70899 https://reactome.org/PathwayBrowser/#/R-MMU-70899 histidine => urocanate + NH4+ IEA Mus musculus 28938 R-MMU-73591 https://reactome.org/PathwayBrowser/#/R-MMU-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Mus musculus 28938 R-MMU-73596 https://reactome.org/PathwayBrowser/#/R-MMU-73596 dCMP + H2O => dUMP + NH4+ IEA Mus musculus 28938 R-MMU-73608 https://reactome.org/PathwayBrowser/#/R-MMU-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Mus musculus 28938 R-MMU-73620 https://reactome.org/PathwayBrowser/#/R-MMU-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Mus musculus 28938 R-MMU-74241 https://reactome.org/PathwayBrowser/#/R-MMU-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Mus musculus 28938 R-MMU-74255 https://reactome.org/PathwayBrowser/#/R-MMU-74255 Guanine + H2O => Xanthine + NH4+ IEA Mus musculus 28938 R-MMU-76590 https://reactome.org/PathwayBrowser/#/R-MMU-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Mus musculus 28938 R-MMU-965079 https://reactome.org/PathwayBrowser/#/R-MMU-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Mus musculus 28938 R-MMU-9754964 https://reactome.org/PathwayBrowser/#/R-MMU-9754964 ADA deamidates RBV IEA Mus musculus 28938 R-PFA-189406 https://reactome.org/PathwayBrowser/#/R-PFA-189406 4 PBGs bind to form HMB IEA Plasmodium falciparum 28938 R-PFA-74241 https://reactome.org/PathwayBrowser/#/R-PFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Plasmodium falciparum 28938 R-PFA-76590 https://reactome.org/PathwayBrowser/#/R-PFA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Plasmodium falciparum 28938 R-PFA-9754964 https://reactome.org/PathwayBrowser/#/R-PFA-9754964 ADA deamidates RBV IEA Plasmodium falciparum 28938 R-RNO-140851 https://reactome.org/PathwayBrowser/#/R-RNO-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Rattus norvegicus 28938 R-RNO-141186 https://reactome.org/PathwayBrowser/#/R-RNO-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Rattus norvegicus 28938 R-RNO-189406 https://reactome.org/PathwayBrowser/#/R-RNO-189406 4 PBGs bind to form HMB IEA Rattus norvegicus 28938 R-RNO-389821 https://reactome.org/PathwayBrowser/#/R-RNO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Rattus norvegicus 28938 R-RNO-444393 https://reactome.org/PathwayBrowser/#/R-RNO-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Rattus norvegicus 28938 R-RNO-444416 https://reactome.org/PathwayBrowser/#/R-RNO-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) IEA Rattus norvegicus 28938 R-RNO-444419 https://reactome.org/PathwayBrowser/#/R-RNO-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Rattus norvegicus 28938 R-RNO-446277 https://reactome.org/PathwayBrowser/#/R-RNO-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Rattus norvegicus 28938 R-RNO-446278 https://reactome.org/PathwayBrowser/#/R-RNO-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Rattus norvegicus 28938 R-RNO-514604 https://reactome.org/PathwayBrowser/#/R-RNO-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Rattus norvegicus 28938 R-RNO-5358475 https://reactome.org/PathwayBrowser/#/R-RNO-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Rattus norvegicus 28938 R-RNO-6799604 https://reactome.org/PathwayBrowser/#/R-RNO-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Rattus norvegicus 28938 R-RNO-6810076 https://reactome.org/PathwayBrowser/#/R-RNO-6810076 DDO oxidizes D-Asp to OA IEA Rattus norvegicus 28938 R-RNO-70555 https://reactome.org/PathwayBrowser/#/R-RNO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Rattus norvegicus 28938 R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Rattus norvegicus 28938 R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Rattus norvegicus 28938 R-RNO-70606 https://reactome.org/PathwayBrowser/#/R-RNO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Rattus norvegicus 28938 R-RNO-70609 https://reactome.org/PathwayBrowser/#/R-RNO-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Rattus norvegicus 28938 R-RNO-70899 https://reactome.org/PathwayBrowser/#/R-RNO-70899 histidine => urocanate + NH4+ IEA Rattus norvegicus 28938 R-RNO-73591 https://reactome.org/PathwayBrowser/#/R-RNO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Rattus norvegicus 28938 R-RNO-73596 https://reactome.org/PathwayBrowser/#/R-RNO-73596 dCMP + H2O => dUMP + NH4+ IEA Rattus norvegicus 28938 R-RNO-73608 https://reactome.org/PathwayBrowser/#/R-RNO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Rattus norvegicus 28938 R-RNO-73620 https://reactome.org/PathwayBrowser/#/R-RNO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Rattus norvegicus 28938 R-RNO-74241 https://reactome.org/PathwayBrowser/#/R-RNO-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Rattus norvegicus 28938 R-RNO-74255 https://reactome.org/PathwayBrowser/#/R-RNO-74255 Guanine + H2O => Xanthine + NH4+ IEA Rattus norvegicus 28938 R-RNO-76590 https://reactome.org/PathwayBrowser/#/R-RNO-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Rattus norvegicus 28938 R-RNO-965079 https://reactome.org/PathwayBrowser/#/R-RNO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Rattus norvegicus 28938 R-RNO-9754964 https://reactome.org/PathwayBrowser/#/R-RNO-9754964 ADA deamidates RBV IEA Rattus norvegicus 28938 R-SCE-189406 https://reactome.org/PathwayBrowser/#/R-SCE-189406 4 PBGs bind to form HMB IEA Saccharomyces cerevisiae 28938 R-SCE-5358475 https://reactome.org/PathwayBrowser/#/R-SCE-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Saccharomyces cerevisiae 28938 R-SCE-70555 https://reactome.org/PathwayBrowser/#/R-SCE-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Saccharomyces cerevisiae 28938 R-SCE-70606 https://reactome.org/PathwayBrowser/#/R-SCE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Saccharomyces cerevisiae 28938 R-SCE-73608 https://reactome.org/PathwayBrowser/#/R-SCE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Saccharomyces cerevisiae 28938 R-SCE-74255 https://reactome.org/PathwayBrowser/#/R-SCE-74255 Guanine + H2O => Xanthine + NH4+ IEA Saccharomyces cerevisiae 28938 R-SCE-76590 https://reactome.org/PathwayBrowser/#/R-SCE-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Saccharomyces cerevisiae 28938 R-SCE-965079 https://reactome.org/PathwayBrowser/#/R-SCE-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Saccharomyces cerevisiae 28938 R-SPO-189406 https://reactome.org/PathwayBrowser/#/R-SPO-189406 4 PBGs bind to form HMB IEA Schizosaccharomyces pombe 28938 R-SPO-389821 https://reactome.org/PathwayBrowser/#/R-SPO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Schizosaccharomyces pombe 28938 R-SPO-5358475 https://reactome.org/PathwayBrowser/#/R-SPO-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Schizosaccharomyces pombe 28938 R-SPO-6810076 https://reactome.org/PathwayBrowser/#/R-SPO-6810076 DDO oxidizes D-Asp to OA IEA Schizosaccharomyces pombe 28938 R-SPO-70555 https://reactome.org/PathwayBrowser/#/R-SPO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Schizosaccharomyces pombe 28938 R-SPO-70606 https://reactome.org/PathwayBrowser/#/R-SPO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Schizosaccharomyces pombe 28938 R-SPO-73591 https://reactome.org/PathwayBrowser/#/R-SPO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Schizosaccharomyces pombe 28938 R-SPO-73608 https://reactome.org/PathwayBrowser/#/R-SPO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Schizosaccharomyces pombe 28938 R-SPO-73620 https://reactome.org/PathwayBrowser/#/R-SPO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Schizosaccharomyces pombe 28938 R-SPO-74255 https://reactome.org/PathwayBrowser/#/R-SPO-74255 Guanine + H2O => Xanthine + NH4+ IEA Schizosaccharomyces pombe 28938 R-SPO-76590 https://reactome.org/PathwayBrowser/#/R-SPO-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Schizosaccharomyces pombe 28938 R-SPO-965079 https://reactome.org/PathwayBrowser/#/R-SPO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Schizosaccharomyces pombe 28938 R-SSC-140851 https://reactome.org/PathwayBrowser/#/R-SSC-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Sus scrofa 28938 R-SSC-141186 https://reactome.org/PathwayBrowser/#/R-SSC-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Sus scrofa 28938 R-SSC-189406 https://reactome.org/PathwayBrowser/#/R-SSC-189406 4 PBGs bind to form HMB IEA Sus scrofa 28938 R-SSC-389821 https://reactome.org/PathwayBrowser/#/R-SSC-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Sus scrofa 28938 R-SSC-444393 https://reactome.org/PathwayBrowser/#/R-SSC-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Sus scrofa 28938 R-SSC-444416 https://reactome.org/PathwayBrowser/#/R-SSC-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) IEA Sus scrofa 28938 R-SSC-444419 https://reactome.org/PathwayBrowser/#/R-SSC-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Sus scrofa 28938 R-SSC-446277 https://reactome.org/PathwayBrowser/#/R-SSC-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Sus scrofa 28938 R-SSC-446278 https://reactome.org/PathwayBrowser/#/R-SSC-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Sus scrofa 28938 R-SSC-514604 https://reactome.org/PathwayBrowser/#/R-SSC-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Sus scrofa 28938 R-SSC-5358475 https://reactome.org/PathwayBrowser/#/R-SSC-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Sus scrofa 28938 R-SSC-6799604 https://reactome.org/PathwayBrowser/#/R-SSC-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Sus scrofa 28938 R-SSC-6810076 https://reactome.org/PathwayBrowser/#/R-SSC-6810076 DDO oxidizes D-Asp to OA IEA Sus scrofa 28938 R-SSC-70555 https://reactome.org/PathwayBrowser/#/R-SSC-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Sus scrofa 28938 R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Sus scrofa 28938 R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Sus scrofa 28938 R-SSC-70606 https://reactome.org/PathwayBrowser/#/R-SSC-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Sus scrofa 28938 R-SSC-70609 https://reactome.org/PathwayBrowser/#/R-SSC-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Sus scrofa 28938 R-SSC-70899 https://reactome.org/PathwayBrowser/#/R-SSC-70899 histidine => urocanate + NH4+ IEA Sus scrofa 28938 R-SSC-73591 https://reactome.org/PathwayBrowser/#/R-SSC-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Sus scrofa 28938 R-SSC-73596 https://reactome.org/PathwayBrowser/#/R-SSC-73596 dCMP + H2O => dUMP + NH4+ IEA Sus scrofa 28938 R-SSC-73608 https://reactome.org/PathwayBrowser/#/R-SSC-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Sus scrofa 28938 R-SSC-73620 https://reactome.org/PathwayBrowser/#/R-SSC-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Sus scrofa 28938 R-SSC-74241 https://reactome.org/PathwayBrowser/#/R-SSC-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Sus scrofa 28938 R-SSC-74255 https://reactome.org/PathwayBrowser/#/R-SSC-74255 Guanine + H2O => Xanthine + NH4+ IEA Sus scrofa 28938 R-SSC-76590 https://reactome.org/PathwayBrowser/#/R-SSC-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Sus scrofa 28938 R-SSC-965079 https://reactome.org/PathwayBrowser/#/R-SSC-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Sus scrofa 28938 R-SSC-9754964 https://reactome.org/PathwayBrowser/#/R-SSC-9754964 ADA deamidates RBV IEA Sus scrofa 28938 R-XTR-189406 https://reactome.org/PathwayBrowser/#/R-XTR-189406 4 PBGs bind to form HMB IEA Xenopus tropicalis 28938 R-XTR-389821 https://reactome.org/PathwayBrowser/#/R-XTR-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Xenopus tropicalis 28938 R-XTR-444393 https://reactome.org/PathwayBrowser/#/R-XTR-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Xenopus tropicalis 28938 R-XTR-444416 https://reactome.org/PathwayBrowser/#/R-XTR-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) IEA Xenopus tropicalis 28938 R-XTR-444419 https://reactome.org/PathwayBrowser/#/R-XTR-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Xenopus tropicalis 28938 R-XTR-446277 https://reactome.org/PathwayBrowser/#/R-XTR-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Xenopus tropicalis 28938 R-XTR-446278 https://reactome.org/PathwayBrowser/#/R-XTR-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Xenopus tropicalis 28938 R-XTR-514604 https://reactome.org/PathwayBrowser/#/R-XTR-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Xenopus tropicalis 28938 R-XTR-5358475 https://reactome.org/PathwayBrowser/#/R-XTR-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Xenopus tropicalis 28938 R-XTR-6799604 https://reactome.org/PathwayBrowser/#/R-XTR-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Xenopus tropicalis 28938 R-XTR-70555 https://reactome.org/PathwayBrowser/#/R-XTR-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Xenopus tropicalis 28938 R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Xenopus tropicalis 28938 R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Xenopus tropicalis 28938 R-XTR-70606 https://reactome.org/PathwayBrowser/#/R-XTR-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Xenopus tropicalis 28938 R-XTR-70609 https://reactome.org/PathwayBrowser/#/R-XTR-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Xenopus tropicalis 28938 R-XTR-70899 https://reactome.org/PathwayBrowser/#/R-XTR-70899 histidine => urocanate + NH4+ IEA Xenopus tropicalis 28938 R-XTR-73596 https://reactome.org/PathwayBrowser/#/R-XTR-73596 dCMP + H2O => dUMP + NH4+ IEA Xenopus tropicalis 28938 R-XTR-73608 https://reactome.org/PathwayBrowser/#/R-XTR-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Xenopus tropicalis 28938 R-XTR-74241 https://reactome.org/PathwayBrowser/#/R-XTR-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Xenopus tropicalis 28938 R-XTR-74255 https://reactome.org/PathwayBrowser/#/R-XTR-74255 Guanine + H2O => Xanthine + NH4+ IEA Xenopus tropicalis 28938 R-XTR-76590 https://reactome.org/PathwayBrowser/#/R-XTR-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Xenopus tropicalis 28938 R-XTR-965079 https://reactome.org/PathwayBrowser/#/R-XTR-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Xenopus tropicalis 28938 R-XTR-9754964 https://reactome.org/PathwayBrowser/#/R-XTR-9754964 ADA deamidates RBV IEA Xenopus tropicalis 28940 R-BTA-209738 https://reactome.org/PathwayBrowser/#/R-BTA-209738 VD3 binds GC IEA Bos taurus 28940 R-BTA-209845 https://reactome.org/PathwayBrowser/#/R-BTA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Bos taurus 28940 R-BTA-8963851 https://reactome.org/PathwayBrowser/#/R-BTA-8963851 VD3 dissociates from GC IEA Bos taurus 28940 R-CEL-209845 https://reactome.org/PathwayBrowser/#/R-CEL-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Caenorhabditis elegans 28940 R-CFA-209738 https://reactome.org/PathwayBrowser/#/R-CFA-209738 VD3 binds GC IEA Canis familiaris 28940 R-CFA-209845 https://reactome.org/PathwayBrowser/#/R-CFA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Canis familiaris 28940 R-CFA-8963851 https://reactome.org/PathwayBrowser/#/R-CFA-8963851 VD3 dissociates from GC IEA Canis familiaris 28940 R-DDI-209845 https://reactome.org/PathwayBrowser/#/R-DDI-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Dictyostelium discoideum 28940 R-DME-209845 https://reactome.org/PathwayBrowser/#/R-DME-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Drosophila melanogaster 28940 R-GGA-209738 https://reactome.org/PathwayBrowser/#/R-GGA-209738 VD3 binds GC IEA Gallus gallus 28940 R-GGA-209845 https://reactome.org/PathwayBrowser/#/R-GGA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Gallus gallus 28940 R-GGA-8963851 https://reactome.org/PathwayBrowser/#/R-GGA-8963851 VD3 dissociates from GC IEA Gallus gallus 28940 R-HSA-209738 https://reactome.org/PathwayBrowser/#/R-HSA-209738 VD3 binds GC TAS Homo sapiens 28940 R-HSA-209754 https://reactome.org/PathwayBrowser/#/R-HSA-209754 Photolytic cleavage and thermal isomerization of 7-dehydroCHOL IEA Homo sapiens 28940 R-HSA-209845 https://reactome.org/PathwayBrowser/#/R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D TAS Homo sapiens 28940 R-HSA-350147 https://reactome.org/PathwayBrowser/#/R-HSA-350147 VD3 translocates from extracellular region to ER membrane TAS Homo sapiens 28940 R-HSA-5602147 https://reactome.org/PathwayBrowser/#/R-HSA-5602147 Defective CYP2R1 does not 25-hydroxylate vitamin D TAS Homo sapiens 28940 R-HSA-8963851 https://reactome.org/PathwayBrowser/#/R-HSA-8963851 VD3 dissociates from GC TAS Homo sapiens 28940 R-HSA-8963872 https://reactome.org/PathwayBrowser/#/R-HSA-8963872 VD3 translocates from ER membrane to extracellular region TAS Homo sapiens 28940 R-MMU-209738 https://reactome.org/PathwayBrowser/#/R-MMU-209738 VD3 binds GC IEA Mus musculus 28940 R-MMU-209845 https://reactome.org/PathwayBrowser/#/R-MMU-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Mus musculus 28940 R-MMU-8963851 https://reactome.org/PathwayBrowser/#/R-MMU-8963851 VD3 dissociates from GC IEA Mus musculus 28940 R-RNO-209738 https://reactome.org/PathwayBrowser/#/R-RNO-209738 VD3 binds GC IEA Rattus norvegicus 28940 R-RNO-209770 https://reactome.org/PathwayBrowser/#/R-RNO-209770 Photolytic cleavage and thermal isomerization of 7-dehydrocholesterol TAS Rattus norvegicus 28940 R-RNO-209845 https://reactome.org/PathwayBrowser/#/R-RNO-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Rattus norvegicus 28940 R-RNO-8963851 https://reactome.org/PathwayBrowser/#/R-RNO-8963851 VD3 dissociates from GC IEA Rattus norvegicus 28940 R-SSC-209738 https://reactome.org/PathwayBrowser/#/R-SSC-209738 VD3 binds GC IEA Sus scrofa 28940 R-SSC-209845 https://reactome.org/PathwayBrowser/#/R-SSC-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Sus scrofa 28940 R-SSC-8963851 https://reactome.org/PathwayBrowser/#/R-SSC-8963851 VD3 dissociates from GC IEA Sus scrofa 28940 R-XTR-209738 https://reactome.org/PathwayBrowser/#/R-XTR-209738 VD3 binds GC IEA Xenopus tropicalis 28940 R-XTR-209845 https://reactome.org/PathwayBrowser/#/R-XTR-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Xenopus tropicalis 28940 R-XTR-8963851 https://reactome.org/PathwayBrowser/#/R-XTR-8963851 VD3 dissociates from GC IEA Xenopus tropicalis 28973 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 28973 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 28973 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 28973 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 28973 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 28973 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 28973 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 28973 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 28973 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 28973 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 28973 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 28973 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 28973 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 28973 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 28973 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 28973 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 28973 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 28973 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 28973 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 28973 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 28973 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 28973 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 28973 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 28973 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 28973 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 28973 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 28973 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 28973 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 28973 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 28973 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 28973 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 28973 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 28973 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 28973 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 28973 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 28973 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 28973 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 28973 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 28973 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 28973 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 28973 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 28973 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 28997 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 28997 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 28997 R-BTA-112033 https://reactome.org/PathwayBrowser/#/R-BTA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Bos taurus 28997 R-BTA-74207 https://reactome.org/PathwayBrowser/#/R-BTA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Bos taurus 28997 R-BTA-74241 https://reactome.org/PathwayBrowser/#/R-BTA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Bos taurus 28997 R-BTA-74242 https://reactome.org/PathwayBrowser/#/R-BTA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Bos taurus 28997 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 28997 R-CEL-112033 https://reactome.org/PathwayBrowser/#/R-CEL-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Caenorhabditis elegans 28997 R-CEL-74241 https://reactome.org/PathwayBrowser/#/R-CEL-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Caenorhabditis elegans 28997 R-CEL-74242 https://reactome.org/PathwayBrowser/#/R-CEL-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Caenorhabditis elegans 28997 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 28997 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 28997 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 28997 R-CFA-112033 https://reactome.org/PathwayBrowser/#/R-CFA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Canis familiaris 28997 R-CFA-74207 https://reactome.org/PathwayBrowser/#/R-CFA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Canis familiaris 28997 R-CFA-74241 https://reactome.org/PathwayBrowser/#/R-CFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Canis familiaris 28997 R-CFA-74242 https://reactome.org/PathwayBrowser/#/R-CFA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Canis familiaris 28997 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 28997 R-DDI-74241 https://reactome.org/PathwayBrowser/#/R-DDI-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Dictyostelium discoideum 28997 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 28997 R-DME-112033 https://reactome.org/PathwayBrowser/#/R-DME-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Drosophila melanogaster 28997 R-DME-74242 https://reactome.org/PathwayBrowser/#/R-DME-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Drosophila melanogaster 28997 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 28997 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 28997 R-DRE-112033 https://reactome.org/PathwayBrowser/#/R-DRE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Danio rerio 28997 R-DRE-74207 https://reactome.org/PathwayBrowser/#/R-DRE-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Danio rerio 28997 R-DRE-74241 https://reactome.org/PathwayBrowser/#/R-DRE-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Danio rerio 28997 R-DRE-74242 https://reactome.org/PathwayBrowser/#/R-DRE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Danio rerio 28997 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 28997 R-GGA-74241 https://reactome.org/PathwayBrowser/#/R-GGA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Gallus gallus 28997 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 28997 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 28997 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 28997 R-HSA-112033 https://reactome.org/PathwayBrowser/#/R-HSA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine TAS Homo sapiens 28997 R-HSA-74207 https://reactome.org/PathwayBrowser/#/R-HSA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) TAS Homo sapiens 28997 R-HSA-74241 https://reactome.org/PathwayBrowser/#/R-HSA-74241 ADA catalyzes the deamination of (deoxy)adenosine TAS Homo sapiens 28997 R-HSA-74242 https://reactome.org/PathwayBrowser/#/R-HSA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 28997 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 28997 R-HSA-9735775 https://reactome.org/PathwayBrowser/#/R-HSA-9735775 Defective PNP does not convert (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 28997 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 28997 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 28997 R-MMU-112033 https://reactome.org/PathwayBrowser/#/R-MMU-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Mus musculus 28997 R-MMU-74207 https://reactome.org/PathwayBrowser/#/R-MMU-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Mus musculus 28997 R-MMU-74241 https://reactome.org/PathwayBrowser/#/R-MMU-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Mus musculus 28997 R-MMU-74242 https://reactome.org/PathwayBrowser/#/R-MMU-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Mus musculus 28997 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 28997 R-PFA-74241 https://reactome.org/PathwayBrowser/#/R-PFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Plasmodium falciparum 28997 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 28997 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 28997 R-RNO-112033 https://reactome.org/PathwayBrowser/#/R-RNO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Rattus norvegicus 28997 R-RNO-74207 https://reactome.org/PathwayBrowser/#/R-RNO-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Rattus norvegicus 28997 R-RNO-74241 https://reactome.org/PathwayBrowser/#/R-RNO-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Rattus norvegicus 28997 R-RNO-74242 https://reactome.org/PathwayBrowser/#/R-RNO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Rattus norvegicus 28997 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 28997 R-SCE-112033 https://reactome.org/PathwayBrowser/#/R-SCE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Saccharomyces cerevisiae 28997 R-SCE-74242 https://reactome.org/PathwayBrowser/#/R-SCE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Saccharomyces cerevisiae 28997 R-SPO-112033 https://reactome.org/PathwayBrowser/#/R-SPO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Schizosaccharomyces pombe 28997 R-SPO-74242 https://reactome.org/PathwayBrowser/#/R-SPO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Schizosaccharomyces pombe 28997 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 28997 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 28997 R-SSC-112033 https://reactome.org/PathwayBrowser/#/R-SSC-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Sus scrofa 28997 R-SSC-74207 https://reactome.org/PathwayBrowser/#/R-SSC-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Sus scrofa 28997 R-SSC-74241 https://reactome.org/PathwayBrowser/#/R-SSC-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Sus scrofa 28997 R-SSC-74242 https://reactome.org/PathwayBrowser/#/R-SSC-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Sus scrofa 28997 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 28997 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 28997 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 28997 R-XTR-112033 https://reactome.org/PathwayBrowser/#/R-XTR-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Xenopus tropicalis 28997 R-XTR-74207 https://reactome.org/PathwayBrowser/#/R-XTR-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Xenopus tropicalis 28997 R-XTR-74241 https://reactome.org/PathwayBrowser/#/R-XTR-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Xenopus tropicalis 28997 R-XTR-74242 https://reactome.org/PathwayBrowser/#/R-XTR-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Xenopus tropicalis 28997 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 29009 R-HSA-175993 https://reactome.org/PathwayBrowser/#/R-HSA-175993 HNMT transfers CH3 group from AdoMet to Hist TAS Homo sapiens 29009 R-HSA-2408544 https://reactome.org/PathwayBrowser/#/R-HSA-2408544 AdoSeMet is converted to AdeSeHCys by MetTrans(1) IEA Homo sapiens 29009 R-RNO-2408545 https://reactome.org/PathwayBrowser/#/R-RNO-2408545 AdoSeMet is converted to AdeSeHCys by MetTrans(2) TAS Rattus norvegicus 29017 R-BTA-1482667 https://reactome.org/PathwayBrowser/#/R-BTA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Bos taurus 29017 R-BTA-1482850 https://reactome.org/PathwayBrowser/#/R-BTA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Bos taurus 29017 R-BTA-1482884 https://reactome.org/PathwayBrowser/#/R-BTA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Bos taurus 29017 R-BTA-1482887 https://reactome.org/PathwayBrowser/#/R-BTA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Bos taurus 29017 R-BTA-1482894 https://reactome.org/PathwayBrowser/#/R-BTA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Bos taurus 29017 R-BTA-1602398 https://reactome.org/PathwayBrowser/#/R-BTA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Bos taurus 29017 R-CEL-1482667 https://reactome.org/PathwayBrowser/#/R-CEL-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Caenorhabditis elegans 29017 R-CEL-1482850 https://reactome.org/PathwayBrowser/#/R-CEL-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 29017 R-CEL-1482884 https://reactome.org/PathwayBrowser/#/R-CEL-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Caenorhabditis elegans 29017 R-CEL-1482887 https://reactome.org/PathwayBrowser/#/R-CEL-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Caenorhabditis elegans 29017 R-CEL-1482894 https://reactome.org/PathwayBrowser/#/R-CEL-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 29017 R-CEL-1602398 https://reactome.org/PathwayBrowser/#/R-CEL-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Caenorhabditis elegans 29017 R-CFA-1482667 https://reactome.org/PathwayBrowser/#/R-CFA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Canis familiaris 29017 R-CFA-1482850 https://reactome.org/PathwayBrowser/#/R-CFA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Canis familiaris 29017 R-CFA-1482884 https://reactome.org/PathwayBrowser/#/R-CFA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Canis familiaris 29017 R-CFA-1482887 https://reactome.org/PathwayBrowser/#/R-CFA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Canis familiaris 29017 R-CFA-1482894 https://reactome.org/PathwayBrowser/#/R-CFA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Canis familiaris 29017 R-CFA-1602398 https://reactome.org/PathwayBrowser/#/R-CFA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Canis familiaris 29017 R-DDI-1482667 https://reactome.org/PathwayBrowser/#/R-DDI-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Dictyostelium discoideum 29017 R-DDI-1482850 https://reactome.org/PathwayBrowser/#/R-DDI-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 29017 R-DDI-1482884 https://reactome.org/PathwayBrowser/#/R-DDI-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Dictyostelium discoideum 29017 R-DDI-1482887 https://reactome.org/PathwayBrowser/#/R-DDI-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Dictyostelium discoideum 29017 R-DDI-1482894 https://reactome.org/PathwayBrowser/#/R-DDI-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 29017 R-DME-1482667 https://reactome.org/PathwayBrowser/#/R-DME-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Drosophila melanogaster 29017 R-DME-1482850 https://reactome.org/PathwayBrowser/#/R-DME-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Drosophila melanogaster 29017 R-DME-1482884 https://reactome.org/PathwayBrowser/#/R-DME-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Drosophila melanogaster 29017 R-DME-1482887 https://reactome.org/PathwayBrowser/#/R-DME-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Drosophila melanogaster 29017 R-DME-1482894 https://reactome.org/PathwayBrowser/#/R-DME-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Drosophila melanogaster 29017 R-DME-1602398 https://reactome.org/PathwayBrowser/#/R-DME-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Drosophila melanogaster 29017 R-DRE-1482571 https://reactome.org/PathwayBrowser/#/R-DRE-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Danio rerio 29017 R-DRE-1482850 https://reactome.org/PathwayBrowser/#/R-DRE-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Danio rerio 29017 R-DRE-1482884 https://reactome.org/PathwayBrowser/#/R-DRE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Danio rerio 29017 R-DRE-1482894 https://reactome.org/PathwayBrowser/#/R-DRE-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Danio rerio 29017 R-DRE-1602398 https://reactome.org/PathwayBrowser/#/R-DRE-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Danio rerio 29017 R-GGA-1482667 https://reactome.org/PathwayBrowser/#/R-GGA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Gallus gallus 29017 R-GGA-1482850 https://reactome.org/PathwayBrowser/#/R-GGA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Gallus gallus 29017 R-GGA-1482884 https://reactome.org/PathwayBrowser/#/R-GGA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Gallus gallus 29017 R-GGA-1482887 https://reactome.org/PathwayBrowser/#/R-GGA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Gallus gallus 29017 R-GGA-1482894 https://reactome.org/PathwayBrowser/#/R-GGA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Gallus gallus 29017 R-GGA-1602398 https://reactome.org/PathwayBrowser/#/R-GGA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Gallus gallus 29017 R-HSA-1482571 https://reactome.org/PathwayBrowser/#/R-HSA-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C TAS Homo sapiens 29017 R-HSA-1482667 https://reactome.org/PathwayBrowser/#/R-HSA-1482667 1-acyl LPE is acylated to PE by LPEAT TAS Homo sapiens 29017 R-HSA-1482850 https://reactome.org/PathwayBrowser/#/R-HSA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) TAS Homo sapiens 29017 R-HSA-1482884 https://reactome.org/PathwayBrowser/#/R-HSA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] TAS Homo sapiens 29017 R-HSA-1482887 https://reactome.org/PathwayBrowser/#/R-HSA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] TAS Homo sapiens 29017 R-HSA-1482894 https://reactome.org/PathwayBrowser/#/R-HSA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) TAS Homo sapiens 29017 R-HSA-1602398 https://reactome.org/PathwayBrowser/#/R-HSA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] TAS Homo sapiens 29017 R-MMU-1482571 https://reactome.org/PathwayBrowser/#/R-MMU-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Mus musculus 29017 R-MMU-1482667 https://reactome.org/PathwayBrowser/#/R-MMU-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Mus musculus 29017 R-MMU-1482850 https://reactome.org/PathwayBrowser/#/R-MMU-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Mus musculus 29017 R-MMU-1482884 https://reactome.org/PathwayBrowser/#/R-MMU-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Mus musculus 29017 R-MMU-1482887 https://reactome.org/PathwayBrowser/#/R-MMU-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Mus musculus 29017 R-MMU-1482894 https://reactome.org/PathwayBrowser/#/R-MMU-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Mus musculus 29017 R-MMU-1602398 https://reactome.org/PathwayBrowser/#/R-MMU-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Mus musculus 29017 R-PFA-1482667 https://reactome.org/PathwayBrowser/#/R-PFA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Plasmodium falciparum 29017 R-RNO-1482571 https://reactome.org/PathwayBrowser/#/R-RNO-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Rattus norvegicus 29017 R-RNO-1482667 https://reactome.org/PathwayBrowser/#/R-RNO-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Rattus norvegicus 29017 R-RNO-1482850 https://reactome.org/PathwayBrowser/#/R-RNO-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Rattus norvegicus 29017 R-RNO-1482884 https://reactome.org/PathwayBrowser/#/R-RNO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Rattus norvegicus 29017 R-RNO-1482887 https://reactome.org/PathwayBrowser/#/R-RNO-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Rattus norvegicus 29017 R-RNO-1482894 https://reactome.org/PathwayBrowser/#/R-RNO-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Rattus norvegicus 29017 R-RNO-1602398 https://reactome.org/PathwayBrowser/#/R-RNO-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Rattus norvegicus 29017 R-SCE-1482571 https://reactome.org/PathwayBrowser/#/R-SCE-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Saccharomyces cerevisiae 29017 R-SCE-1482667 https://reactome.org/PathwayBrowser/#/R-SCE-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Saccharomyces cerevisiae 29017 R-SCE-1482850 https://reactome.org/PathwayBrowser/#/R-SCE-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 29017 R-SCE-1482884 https://reactome.org/PathwayBrowser/#/R-SCE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Saccharomyces cerevisiae 29017 R-SCE-1482894 https://reactome.org/PathwayBrowser/#/R-SCE-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 29017 R-SPO-1482571 https://reactome.org/PathwayBrowser/#/R-SPO-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Schizosaccharomyces pombe 29017 R-SPO-1482667 https://reactome.org/PathwayBrowser/#/R-SPO-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Schizosaccharomyces pombe 29017 R-SPO-1482884 https://reactome.org/PathwayBrowser/#/R-SPO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Schizosaccharomyces pombe 29017 R-SSC-1482667 https://reactome.org/PathwayBrowser/#/R-SSC-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Sus scrofa 29017 R-SSC-1482850 https://reactome.org/PathwayBrowser/#/R-SSC-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Sus scrofa 29017 R-SSC-1482884 https://reactome.org/PathwayBrowser/#/R-SSC-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Sus scrofa 29017 R-SSC-1482887 https://reactome.org/PathwayBrowser/#/R-SSC-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Sus scrofa 29017 R-SSC-1482894 https://reactome.org/PathwayBrowser/#/R-SSC-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Sus scrofa 29017 R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa 29017 R-XTR-1482667 https://reactome.org/PathwayBrowser/#/R-XTR-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Xenopus tropicalis 29017 R-XTR-1482850 https://reactome.org/PathwayBrowser/#/R-XTR-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Xenopus tropicalis 29017 R-XTR-1482884 https://reactome.org/PathwayBrowser/#/R-XTR-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Xenopus tropicalis 29017 R-XTR-1482887 https://reactome.org/PathwayBrowser/#/R-XTR-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Xenopus tropicalis 29017 R-XTR-1482894 https://reactome.org/PathwayBrowser/#/R-XTR-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Xenopus tropicalis 29017 R-XTR-1602398 https://reactome.org/PathwayBrowser/#/R-XTR-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Xenopus tropicalis 29025 R-BTA-4085217 https://reactome.org/PathwayBrowser/#/R-BTA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Bos taurus 29025 R-CFA-4085217 https://reactome.org/PathwayBrowser/#/R-CFA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Canis familiaris 29025 R-DRE-4085217 https://reactome.org/PathwayBrowser/#/R-DRE-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Danio rerio 29025 R-GGA-4085217 https://reactome.org/PathwayBrowser/#/R-GGA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Gallus gallus 29025 R-HSA-4085217 https://reactome.org/PathwayBrowser/#/R-HSA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate TAS Homo sapiens 29025 R-MMU-4085217 https://reactome.org/PathwayBrowser/#/R-MMU-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Mus musculus 29025 R-RNO-4085217 https://reactome.org/PathwayBrowser/#/R-RNO-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Rattus norvegicus 29025 R-SSC-4085217 https://reactome.org/PathwayBrowser/#/R-SSC-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Sus scrofa 29025 R-XTR-4085217 https://reactome.org/PathwayBrowser/#/R-XTR-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Xenopus tropicalis 29032 R-BTA-196857 https://reactome.org/PathwayBrowser/#/R-BTA-196857 PANK2 phosphorylates PanK IEA Bos taurus 29032 R-BTA-199203 https://reactome.org/PathwayBrowser/#/R-BTA-199203 PANK1/3 phosphorylate PanK IEA Bos taurus 29032 R-BTA-199206 https://reactome.org/PathwayBrowser/#/R-BTA-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Bos taurus 29032 R-BTA-429581 https://reactome.org/PathwayBrowser/#/R-BTA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Bos taurus 29032 R-BTA-8938300 https://reactome.org/PathwayBrowser/#/R-BTA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Bos taurus 29032 R-CFA-196857 https://reactome.org/PathwayBrowser/#/R-CFA-196857 PANK2 phosphorylates PanK IEA Canis familiaris 29032 R-CFA-199203 https://reactome.org/PathwayBrowser/#/R-CFA-199203 PANK1/3 phosphorylate PanK IEA Canis familiaris 29032 R-CFA-199206 https://reactome.org/PathwayBrowser/#/R-CFA-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Canis familiaris 29032 R-CFA-429581 https://reactome.org/PathwayBrowser/#/R-CFA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Canis familiaris 29032 R-CFA-8938300 https://reactome.org/PathwayBrowser/#/R-CFA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Canis familiaris 29032 R-DDI-8938300 https://reactome.org/PathwayBrowser/#/R-DDI-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Dictyostelium discoideum 29032 R-DME-196857 https://reactome.org/PathwayBrowser/#/R-DME-196857 PANK2 phosphorylates PanK IEA Drosophila melanogaster 29032 R-DME-199203 https://reactome.org/PathwayBrowser/#/R-DME-199203 PANK1/3 phosphorylate PanK IEA Drosophila melanogaster 29032 R-DRE-199203 https://reactome.org/PathwayBrowser/#/R-DRE-199203 PANK1/3 phosphorylate PanK IEA Danio rerio 29032 R-DRE-199206 https://reactome.org/PathwayBrowser/#/R-DRE-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Danio rerio 29032 R-DRE-429581 https://reactome.org/PathwayBrowser/#/R-DRE-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Danio rerio 29032 R-GGA-196857 https://reactome.org/PathwayBrowser/#/R-GGA-196857 PANK2 phosphorylates PanK IEA Gallus gallus 29032 R-GGA-199203 https://reactome.org/PathwayBrowser/#/R-GGA-199203 PANK1/3 phosphorylate PanK IEA Gallus gallus 29032 R-GGA-199206 https://reactome.org/PathwayBrowser/#/R-GGA-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Gallus gallus 29032 R-GGA-429581 https://reactome.org/PathwayBrowser/#/R-GGA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Gallus gallus 29032 R-GGA-8938300 https://reactome.org/PathwayBrowser/#/R-GGA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Gallus gallus 29032 R-HSA-196857 https://reactome.org/PathwayBrowser/#/R-HSA-196857 PANK2 phosphorylates PanK TAS Homo sapiens 29032 R-HSA-199203 https://reactome.org/PathwayBrowser/#/R-HSA-199203 PANK1/3 phosphorylate PanK TAS Homo sapiens 29032 R-HSA-199206 https://reactome.org/PathwayBrowser/#/R-HSA-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol TAS Homo sapiens 29032 R-HSA-429581 https://reactome.org/PathwayBrowser/#/R-HSA-429581 SLC5A6 transports vitamins from extracellular region to cytosol TAS Homo sapiens 29032 R-HSA-8938300 https://reactome.org/PathwayBrowser/#/R-HSA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET TAS Homo sapiens 29032 R-MMU-196857 https://reactome.org/PathwayBrowser/#/R-MMU-196857 PANK2 phosphorylates PanK IEA Mus musculus 29032 R-MMU-199203 https://reactome.org/PathwayBrowser/#/R-MMU-199203 PANK1/3 phosphorylate PanK IEA Mus musculus 29032 R-MMU-199206 https://reactome.org/PathwayBrowser/#/R-MMU-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Mus musculus 29032 R-MMU-429581 https://reactome.org/PathwayBrowser/#/R-MMU-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Mus musculus 29032 R-MMU-8938300 https://reactome.org/PathwayBrowser/#/R-MMU-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Mus musculus 29032 R-RNO-196857 https://reactome.org/PathwayBrowser/#/R-RNO-196857 PANK2 phosphorylates PanK IEA Rattus norvegicus 29032 R-RNO-199203 https://reactome.org/PathwayBrowser/#/R-RNO-199203 PANK1/3 phosphorylate PanK IEA Rattus norvegicus 29032 R-RNO-199206 https://reactome.org/PathwayBrowser/#/R-RNO-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Rattus norvegicus 29032 R-RNO-429581 https://reactome.org/PathwayBrowser/#/R-RNO-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Rattus norvegicus 29032 R-RNO-8938300 https://reactome.org/PathwayBrowser/#/R-RNO-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Rattus norvegicus 29032 R-SSC-196857 https://reactome.org/PathwayBrowser/#/R-SSC-196857 PANK2 phosphorylates PanK IEA Sus scrofa 29032 R-SSC-199203 https://reactome.org/PathwayBrowser/#/R-SSC-199203 PANK1/3 phosphorylate PanK IEA Sus scrofa 29032 R-SSC-199206 https://reactome.org/PathwayBrowser/#/R-SSC-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Sus scrofa 29032 R-SSC-429581 https://reactome.org/PathwayBrowser/#/R-SSC-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Sus scrofa 29032 R-SSC-8938300 https://reactome.org/PathwayBrowser/#/R-SSC-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Sus scrofa 29032 R-XTR-196857 https://reactome.org/PathwayBrowser/#/R-XTR-196857 PANK2 phosphorylates PanK IEA Xenopus tropicalis 29032 R-XTR-199206 https://reactome.org/PathwayBrowser/#/R-XTR-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Xenopus tropicalis 29032 R-XTR-429581 https://reactome.org/PathwayBrowser/#/R-XTR-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Xenopus tropicalis 29032 R-XTR-8938300 https://reactome.org/PathwayBrowser/#/R-XTR-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Xenopus tropicalis 29033 R-BTA-111285 https://reactome.org/PathwayBrowser/#/R-BTA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Bos taurus 29033 R-BTA-111289 https://reactome.org/PathwayBrowser/#/R-BTA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Bos taurus 29033 R-BTA-1234159 https://reactome.org/PathwayBrowser/#/R-BTA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Bos taurus 29033 R-BTA-1234163 https://reactome.org/PathwayBrowser/#/R-BTA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Bos taurus 29033 R-BTA-1234164 https://reactome.org/PathwayBrowser/#/R-BTA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Bos taurus 29033 R-BTA-1234165 https://reactome.org/PathwayBrowser/#/R-BTA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Bos taurus 29033 R-BTA-1234173 https://reactome.org/PathwayBrowser/#/R-BTA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Bos taurus 29033 R-BTA-1234177 https://reactome.org/PathwayBrowser/#/R-BTA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Bos taurus 29033 R-BTA-1234181 https://reactome.org/PathwayBrowser/#/R-BTA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Bos taurus 29033 R-BTA-1234183 https://reactome.org/PathwayBrowser/#/R-BTA-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Bos taurus 29033 R-BTA-1237119 https://reactome.org/PathwayBrowser/#/R-BTA-1237119 Acireductone is oxidized to MOB IEA Bos taurus 29033 R-BTA-1362408 https://reactome.org/PathwayBrowser/#/R-BTA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Bos taurus 29033 R-BTA-1362416 https://reactome.org/PathwayBrowser/#/R-BTA-1362416 Frataxin binds iron IEA Bos taurus 29033 R-BTA-1562626 https://reactome.org/PathwayBrowser/#/R-BTA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Bos taurus 29033 R-BTA-1614645 https://reactome.org/PathwayBrowser/#/R-BTA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Bos taurus 29033 R-BTA-1650808 https://reactome.org/PathwayBrowser/#/R-BTA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Bos taurus 29033 R-BTA-180038 https://reactome.org/PathwayBrowser/#/R-BTA-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function IEA Bos taurus 29033 R-BTA-189398 https://reactome.org/PathwayBrowser/#/R-BTA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Bos taurus 29033 R-BTA-189465 https://reactome.org/PathwayBrowser/#/R-BTA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Bos taurus 29033 R-BTA-1980233 https://reactome.org/PathwayBrowser/#/R-BTA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Bos taurus 29033 R-BTA-1981104 https://reactome.org/PathwayBrowser/#/R-BTA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Bos taurus 29033 R-BTA-1981128 https://reactome.org/PathwayBrowser/#/R-BTA-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Bos taurus 29033 R-BTA-1981157 https://reactome.org/PathwayBrowser/#/R-BTA-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Bos taurus 29033 R-BTA-199803 https://reactome.org/PathwayBrowser/#/R-BTA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Bos taurus 29033 R-BTA-204662 https://reactome.org/PathwayBrowser/#/R-BTA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Bos taurus 29033 R-BTA-209823 https://reactome.org/PathwayBrowser/#/R-BTA-209823 Tyrosine is hydroxylated to dopa IEA Bos taurus 29033 R-BTA-209828 https://reactome.org/PathwayBrowser/#/R-BTA-209828 Tryptophan is hydroxylated IEA Bos taurus 29033 R-BTA-2161768 https://reactome.org/PathwayBrowser/#/R-BTA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Bos taurus 29033 R-BTA-2161775 https://reactome.org/PathwayBrowser/#/R-BTA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Bos taurus 29033 R-BTA-2161794 https://reactome.org/PathwayBrowser/#/R-BTA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Bos taurus 29033 R-BTA-2161907 https://reactome.org/PathwayBrowser/#/R-BTA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Bos taurus 29033 R-BTA-2161917 https://reactome.org/PathwayBrowser/#/R-BTA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Bos taurus 29033 R-BTA-2161948 https://reactome.org/PathwayBrowser/#/R-BTA-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Bos taurus 29033 R-BTA-2161950 https://reactome.org/PathwayBrowser/#/R-BTA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Bos taurus 29033 R-BTA-2161964 https://reactome.org/PathwayBrowser/#/R-BTA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Bos taurus 29033 R-BTA-2162002 https://reactome.org/PathwayBrowser/#/R-BTA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Bos taurus 29033 R-BTA-2162019 https://reactome.org/PathwayBrowser/#/R-BTA-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Bos taurus 29033 R-BTA-2162186 https://reactome.org/PathwayBrowser/#/R-BTA-2162186 COQ3 methylates DeMQ10H2 IEA Bos taurus 29033 R-BTA-2162188 https://reactome.org/PathwayBrowser/#/R-BTA-2162188 COQ5 methylates MDMQ10H2 IEA Bos taurus 29033 R-BTA-2162193 https://reactome.org/PathwayBrowser/#/R-BTA-2162193 COQ3 methylates DHDB IEA Bos taurus 29033 R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 29033 R-BTA-2172678 https://reactome.org/PathwayBrowser/#/R-BTA-2172678 PHF8 demethylates histone H4K20me1 IEA Bos taurus 29033 R-BTA-2245218 https://reactome.org/PathwayBrowser/#/R-BTA-2245218 CDK1 phosphorylates PHF8 IEA Bos taurus 29033 R-BTA-2301205 https://reactome.org/PathwayBrowser/#/R-BTA-2301205 SETD8 monomethylates histone H4 IEA Bos taurus 29033 R-BTA-265296 https://reactome.org/PathwayBrowser/#/R-BTA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Bos taurus 29033 R-BTA-266050 https://reactome.org/PathwayBrowser/#/R-BTA-266050 LTA4 is converted to LTC4 by LTC4S IEA Bos taurus 29033 R-BTA-266051 https://reactome.org/PathwayBrowser/#/R-BTA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Bos taurus 29033 R-BTA-3222593 https://reactome.org/PathwayBrowser/#/R-BTA-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Bos taurus 29033 R-BTA-389639 https://reactome.org/PathwayBrowser/#/R-BTA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Bos taurus 29033 R-BTA-428259 https://reactome.org/PathwayBrowser/#/R-BTA-428259 DEGS1 dehydrogenates dihydroceramide IEA Bos taurus 29033 R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 29033 R-BTA-429016 https://reactome.org/PathwayBrowser/#/R-BTA-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Bos taurus 29033 R-BTA-435171 https://reactome.org/PathwayBrowser/#/R-BTA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Bos taurus 29033 R-BTA-435349 https://reactome.org/PathwayBrowser/#/R-BTA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Bos taurus 29033 R-BTA-442368 https://reactome.org/PathwayBrowser/#/R-BTA-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Bos taurus 29033 R-BTA-5164399 https://reactome.org/PathwayBrowser/#/R-BTA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Bos taurus 29033 R-BTA-5678327 https://reactome.org/PathwayBrowser/#/R-BTA-5678327 MIOX oxidises Ins to GlcA IEA Bos taurus 29033 R-BTA-5690873 https://reactome.org/PathwayBrowser/#/R-BTA-5690873 ACO1 binds 4Fe-4S IEA Bos taurus 29033 R-BTA-5691107 https://reactome.org/PathwayBrowser/#/R-BTA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Bos taurus 29033 R-BTA-5693761 https://reactome.org/PathwayBrowser/#/R-BTA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Bos taurus 29033 R-BTA-6814153 https://reactome.org/PathwayBrowser/#/R-BTA-6814153 ADO oxidises 2AET to HTAU IEA Bos taurus 29033 R-BTA-71118 https://reactome.org/PathwayBrowser/#/R-BTA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Bos taurus 29033 R-BTA-71163 https://reactome.org/PathwayBrowser/#/R-BTA-71163 HPD dioxygenates HPP IEA Bos taurus 29033 R-BTA-71164 https://reactome.org/PathwayBrowser/#/R-BTA-71164 HGD dioxygenates homogentisate IEA Bos taurus 29033 R-BTA-71218 https://reactome.org/PathwayBrowser/#/R-BTA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Bos taurus 29033 R-BTA-71241 https://reactome.org/PathwayBrowser/#/R-BTA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Bos taurus 29033 R-BTA-71261 https://reactome.org/PathwayBrowser/#/R-BTA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Bos taurus 29033 R-BTA-71303 https://reactome.org/PathwayBrowser/#/R-BTA-71303 RPE dimers isomerise RU5P to XY5P IEA Bos taurus 29033 R-BTA-73815 https://reactome.org/PathwayBrowser/#/R-BTA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Bos taurus 29033 R-BTA-8857692 https://reactome.org/PathwayBrowser/#/R-BTA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Bos taurus 29033 R-BTA-8948219 https://reactome.org/PathwayBrowser/#/R-BTA-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Bos taurus 29033 R-BTA-8948222 https://reactome.org/PathwayBrowser/#/R-BTA-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Bos taurus 29033 R-BTA-8948224 https://reactome.org/PathwayBrowser/#/R-BTA-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Bos taurus 29033 R-BTA-8948232 https://reactome.org/PathwayBrowser/#/R-BTA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Bos taurus 29033 R-BTA-8979071 https://reactome.org/PathwayBrowser/#/R-BTA-8979071 KDM6B binds iron IEA Bos taurus 29033 R-BTA-9020274 https://reactome.org/PathwayBrowser/#/R-BTA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Bos taurus 29033 R-BTA-9024983 https://reactome.org/PathwayBrowser/#/R-BTA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Bos taurus 29033 R-BTA-9025957 https://reactome.org/PathwayBrowser/#/R-BTA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Bos taurus 29033 R-BTA-9026006 https://reactome.org/PathwayBrowser/#/R-BTA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Bos taurus 29033 R-BTA-9026007 https://reactome.org/PathwayBrowser/#/R-BTA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Bos taurus 29033 R-BTA-904830 https://reactome.org/PathwayBrowser/#/R-BTA-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Bos taurus 29033 R-BTA-917805 https://reactome.org/PathwayBrowser/#/R-BTA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Bos taurus 29033 R-BTA-917811 https://reactome.org/PathwayBrowser/#/R-BTA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Bos taurus 29033 R-BTA-917891 https://reactome.org/PathwayBrowser/#/R-BTA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Bos taurus 29033 R-BTA-917933 https://reactome.org/PathwayBrowser/#/R-BTA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Bos taurus 29033 R-BTA-917936 https://reactome.org/PathwayBrowser/#/R-BTA-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Bos taurus 29033 R-BTA-9629578 https://reactome.org/PathwayBrowser/#/R-BTA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Bos taurus 29033 R-BTA-9629591 https://reactome.org/PathwayBrowser/#/R-BTA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Bos taurus 29033 R-BTA-9629869 https://reactome.org/PathwayBrowser/#/R-BTA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Bos taurus 29033 R-BTA-9629888 https://reactome.org/PathwayBrowser/#/R-BTA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Bos taurus 29033 R-BTA-9629946 https://reactome.org/PathwayBrowser/#/R-BTA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Bos taurus 29033 R-BTA-9630022 https://reactome.org/PathwayBrowser/#/R-BTA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Bos taurus 29033 R-BTA-9630769 https://reactome.org/PathwayBrowser/#/R-BTA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Bos taurus 29033 R-BTA-9630967 https://reactome.org/PathwayBrowser/#/R-BTA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Bos taurus 29033 R-BTA-9630993 https://reactome.org/PathwayBrowser/#/R-BTA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Bos taurus 29033 R-BTA-9631356 https://reactome.org/PathwayBrowser/#/R-BTA-9631356 ASPH:Fe2+ hydroxylates an aspartate residue of F9 TAS Bos taurus 29033 R-BTA-9707186 https://reactome.org/PathwayBrowser/#/R-BTA-9707186 ALOX5 binds ALOX5 inhibitors IEA Bos taurus 29033 R-BTA-975635 https://reactome.org/PathwayBrowser/#/R-BTA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Bos taurus 29033 R-BTA-9854368 https://reactome.org/PathwayBrowser/#/R-BTA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Bos taurus 29033 R-BTA-9854405 https://reactome.org/PathwayBrowser/#/R-BTA-9854405 Frataxin transfers Fe2+ to ACO2 IEA Bos taurus 29033 R-BTA-9854984 https://reactome.org/PathwayBrowser/#/R-BTA-9854984 Transfer of Fe-S clusters to SDHB IEA Bos taurus 29033 R-CEL-111285 https://reactome.org/PathwayBrowser/#/R-CEL-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Caenorhabditis elegans 29033 R-CEL-111289 https://reactome.org/PathwayBrowser/#/R-CEL-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Caenorhabditis elegans 29033 R-CEL-1234159 https://reactome.org/PathwayBrowser/#/R-CEL-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Caenorhabditis elegans 29033 R-CEL-1234163 https://reactome.org/PathwayBrowser/#/R-CEL-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Caenorhabditis elegans 29033 R-CEL-1234165 https://reactome.org/PathwayBrowser/#/R-CEL-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 29033 R-CEL-1234173 https://reactome.org/PathwayBrowser/#/R-CEL-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 29033 R-CEL-1234177 https://reactome.org/PathwayBrowser/#/R-CEL-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 29033 R-CEL-1234181 https://reactome.org/PathwayBrowser/#/R-CEL-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 29033 R-CEL-1234183 https://reactome.org/PathwayBrowser/#/R-CEL-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Caenorhabditis elegans 29033 R-CEL-1237119 https://reactome.org/PathwayBrowser/#/R-CEL-1237119 Acireductone is oxidized to MOB IEA Caenorhabditis elegans 29033 R-CEL-1362408 https://reactome.org/PathwayBrowser/#/R-CEL-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Caenorhabditis elegans 29033 R-CEL-1362416 https://reactome.org/PathwayBrowser/#/R-CEL-1362416 Frataxin binds iron IEA Caenorhabditis elegans 29033 R-CEL-1562626 https://reactome.org/PathwayBrowser/#/R-CEL-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Caenorhabditis elegans 29033 R-CEL-1614645 https://reactome.org/PathwayBrowser/#/R-CEL-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Caenorhabditis elegans 29033 R-CEL-1650808 https://reactome.org/PathwayBrowser/#/R-CEL-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Caenorhabditis elegans 29033 R-CEL-189465 https://reactome.org/PathwayBrowser/#/R-CEL-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Caenorhabditis elegans 29033 R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 29033 R-CEL-1981104 https://reactome.org/PathwayBrowser/#/R-CEL-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Caenorhabditis elegans 29033 R-CEL-1981128 https://reactome.org/PathwayBrowser/#/R-CEL-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Caenorhabditis elegans 29033 R-CEL-1981157 https://reactome.org/PathwayBrowser/#/R-CEL-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Caenorhabditis elegans 29033 R-CEL-199803 https://reactome.org/PathwayBrowser/#/R-CEL-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Caenorhabditis elegans 29033 R-CEL-204662 https://reactome.org/PathwayBrowser/#/R-CEL-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Caenorhabditis elegans 29033 R-CEL-209823 https://reactome.org/PathwayBrowser/#/R-CEL-209823 Tyrosine is hydroxylated to dopa IEA Caenorhabditis elegans 29033 R-CEL-209828 https://reactome.org/PathwayBrowser/#/R-CEL-209828 Tryptophan is hydroxylated IEA Caenorhabditis elegans 29033 R-CEL-2162186 https://reactome.org/PathwayBrowser/#/R-CEL-2162186 COQ3 methylates DeMQ10H2 IEA Caenorhabditis elegans 29033 R-CEL-2162188 https://reactome.org/PathwayBrowser/#/R-CEL-2162188 COQ5 methylates MDMQ10H2 IEA Caenorhabditis elegans 29033 R-CEL-2162193 https://reactome.org/PathwayBrowser/#/R-CEL-2162193 COQ3 methylates DHDB IEA Caenorhabditis elegans 29033 R-CEL-2172678 https://reactome.org/PathwayBrowser/#/R-CEL-2172678 PHF8 demethylates histone H4K20me1 IEA Caenorhabditis elegans 29033 R-CEL-2301205 https://reactome.org/PathwayBrowser/#/R-CEL-2301205 SETD8 monomethylates histone H4 IEA Caenorhabditis elegans 29033 R-CEL-3222593 https://reactome.org/PathwayBrowser/#/R-CEL-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Caenorhabditis elegans 29033 R-CEL-389639 https://reactome.org/PathwayBrowser/#/R-CEL-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Caenorhabditis elegans 29033 R-CEL-428259 https://reactome.org/PathwayBrowser/#/R-CEL-428259 DEGS1 dehydrogenates dihydroceramide IEA Caenorhabditis elegans 29033 R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 29033 R-CEL-435171 https://reactome.org/PathwayBrowser/#/R-CEL-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Caenorhabditis elegans 29033 R-CEL-435349 https://reactome.org/PathwayBrowser/#/R-CEL-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 29033 R-CEL-5164399 https://reactome.org/PathwayBrowser/#/R-CEL-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Caenorhabditis elegans 29033 R-CEL-5678327 https://reactome.org/PathwayBrowser/#/R-CEL-5678327 MIOX oxidises Ins to GlcA IEA Caenorhabditis elegans 29033 R-CEL-5690873 https://reactome.org/PathwayBrowser/#/R-CEL-5690873 ACO1 binds 4Fe-4S IEA Caenorhabditis elegans 29033 R-CEL-5691107 https://reactome.org/PathwayBrowser/#/R-CEL-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Caenorhabditis elegans 29033 R-CEL-5693761 https://reactome.org/PathwayBrowser/#/R-CEL-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Caenorhabditis elegans 29033 R-CEL-6814153 https://reactome.org/PathwayBrowser/#/R-CEL-6814153 ADO oxidises 2AET to HTAU IEA Caenorhabditis elegans 29033 R-CEL-71118 https://reactome.org/PathwayBrowser/#/R-CEL-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Caenorhabditis elegans 29033 R-CEL-71163 https://reactome.org/PathwayBrowser/#/R-CEL-71163 HPD dioxygenates HPP IEA Caenorhabditis elegans 29033 R-CEL-71164 https://reactome.org/PathwayBrowser/#/R-CEL-71164 HGD dioxygenates homogentisate IEA Caenorhabditis elegans 29033 R-CEL-71218 https://reactome.org/PathwayBrowser/#/R-CEL-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Caenorhabditis elegans 29033 R-CEL-71241 https://reactome.org/PathwayBrowser/#/R-CEL-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Caenorhabditis elegans 29033 R-CEL-71261 https://reactome.org/PathwayBrowser/#/R-CEL-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Caenorhabditis elegans 29033 R-CEL-71303 https://reactome.org/PathwayBrowser/#/R-CEL-71303 RPE dimers isomerise RU5P to XY5P IEA Caenorhabditis elegans 29033 R-CEL-73815 https://reactome.org/PathwayBrowser/#/R-CEL-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Caenorhabditis elegans 29033 R-CEL-8948219 https://reactome.org/PathwayBrowser/#/R-CEL-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Caenorhabditis elegans 29033 R-CEL-8948222 https://reactome.org/PathwayBrowser/#/R-CEL-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Caenorhabditis elegans 29033 R-CEL-8948224 https://reactome.org/PathwayBrowser/#/R-CEL-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Caenorhabditis elegans 29033 R-CEL-8948232 https://reactome.org/PathwayBrowser/#/R-CEL-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Caenorhabditis elegans 29033 R-CEL-8979071 https://reactome.org/PathwayBrowser/#/R-CEL-8979071 KDM6B binds iron IEA Caenorhabditis elegans 29033 R-CEL-917805 https://reactome.org/PathwayBrowser/#/R-CEL-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Caenorhabditis elegans 29033 R-CEL-917936 https://reactome.org/PathwayBrowser/#/R-CEL-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Caenorhabditis elegans 29033 R-CEL-9629869 https://reactome.org/PathwayBrowser/#/R-CEL-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Caenorhabditis elegans 29033 R-CEL-9629888 https://reactome.org/PathwayBrowser/#/R-CEL-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Caenorhabditis elegans 29033 R-CEL-9629946 https://reactome.org/PathwayBrowser/#/R-CEL-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Caenorhabditis elegans 29033 R-CEL-9630022 https://reactome.org/PathwayBrowser/#/R-CEL-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Caenorhabditis elegans 29033 R-CEL-9630769 https://reactome.org/PathwayBrowser/#/R-CEL-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Caenorhabditis elegans 29033 R-CEL-9630993 https://reactome.org/PathwayBrowser/#/R-CEL-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Caenorhabditis elegans 29033 R-CEL-975635 https://reactome.org/PathwayBrowser/#/R-CEL-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Caenorhabditis elegans 29033 R-CEL-9854368 https://reactome.org/PathwayBrowser/#/R-CEL-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Caenorhabditis elegans 29033 R-CEL-9854405 https://reactome.org/PathwayBrowser/#/R-CEL-9854405 Frataxin transfers Fe2+ to ACO2 IEA Caenorhabditis elegans 29033 R-CFA-111285 https://reactome.org/PathwayBrowser/#/R-CFA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Canis familiaris 29033 R-CFA-111289 https://reactome.org/PathwayBrowser/#/R-CFA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Canis familiaris 29033 R-CFA-1234159 https://reactome.org/PathwayBrowser/#/R-CFA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Canis familiaris 29033 R-CFA-1234163 https://reactome.org/PathwayBrowser/#/R-CFA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Canis familiaris 29033 R-CFA-1234164 https://reactome.org/PathwayBrowser/#/R-CFA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Canis familiaris 29033 R-CFA-1234165 https://reactome.org/PathwayBrowser/#/R-CFA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 29033 R-CFA-1234173 https://reactome.org/PathwayBrowser/#/R-CFA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 29033 R-CFA-1234177 https://reactome.org/PathwayBrowser/#/R-CFA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 29033 R-CFA-1234181 https://reactome.org/PathwayBrowser/#/R-CFA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 29033 R-CFA-1234183 https://reactome.org/PathwayBrowser/#/R-CFA-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Canis familiaris 29033 R-CFA-1237119 https://reactome.org/PathwayBrowser/#/R-CFA-1237119 Acireductone is oxidized to MOB IEA Canis familiaris 29033 R-CFA-1362408 https://reactome.org/PathwayBrowser/#/R-CFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Canis familiaris 29033 R-CFA-1362416 https://reactome.org/PathwayBrowser/#/R-CFA-1362416 Frataxin binds iron IEA Canis familiaris 29033 R-CFA-1562626 https://reactome.org/PathwayBrowser/#/R-CFA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Canis familiaris 29033 R-CFA-1614645 https://reactome.org/PathwayBrowser/#/R-CFA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Canis familiaris 29033 R-CFA-1650808 https://reactome.org/PathwayBrowser/#/R-CFA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Canis familiaris 29033 R-CFA-180038 https://reactome.org/PathwayBrowser/#/R-CFA-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function IEA Canis familiaris 29033 R-CFA-189398 https://reactome.org/PathwayBrowser/#/R-CFA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Canis familiaris 29033 R-CFA-189465 https://reactome.org/PathwayBrowser/#/R-CFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Canis familiaris 29033 R-CFA-1980233 https://reactome.org/PathwayBrowser/#/R-CFA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Canis familiaris 29033 R-CFA-1981104 https://reactome.org/PathwayBrowser/#/R-CFA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Canis familiaris 29033 R-CFA-1981128 https://reactome.org/PathwayBrowser/#/R-CFA-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Canis familiaris 29033 R-CFA-1981157 https://reactome.org/PathwayBrowser/#/R-CFA-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Canis familiaris 29033 R-CFA-199803 https://reactome.org/PathwayBrowser/#/R-CFA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Canis familiaris 29033 R-CFA-204662 https://reactome.org/PathwayBrowser/#/R-CFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Canis familiaris 29033 R-CFA-209823 https://reactome.org/PathwayBrowser/#/R-CFA-209823 Tyrosine is hydroxylated to dopa IEA Canis familiaris 29033 R-CFA-209828 https://reactome.org/PathwayBrowser/#/R-CFA-209828 Tryptophan is hydroxylated IEA Canis familiaris 29033 R-CFA-2161768 https://reactome.org/PathwayBrowser/#/R-CFA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Canis familiaris 29033 R-CFA-2161775 https://reactome.org/PathwayBrowser/#/R-CFA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Canis familiaris 29033 R-CFA-2161794 https://reactome.org/PathwayBrowser/#/R-CFA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Canis familiaris 29033 R-CFA-2161907 https://reactome.org/PathwayBrowser/#/R-CFA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Canis familiaris 29033 R-CFA-2161917 https://reactome.org/PathwayBrowser/#/R-CFA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Canis familiaris 29033 R-CFA-2161948 https://reactome.org/PathwayBrowser/#/R-CFA-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Canis familiaris 29033 R-CFA-2161950 https://reactome.org/PathwayBrowser/#/R-CFA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Canis familiaris 29033 R-CFA-2161964 https://reactome.org/PathwayBrowser/#/R-CFA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Canis familiaris 29033 R-CFA-2162002 https://reactome.org/PathwayBrowser/#/R-CFA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Canis familiaris 29033 R-CFA-2162019 https://reactome.org/PathwayBrowser/#/R-CFA-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Canis familiaris 29033 R-CFA-2162186 https://reactome.org/PathwayBrowser/#/R-CFA-2162186 COQ3 methylates DeMQ10H2 IEA Canis familiaris 29033 R-CFA-2162188 https://reactome.org/PathwayBrowser/#/R-CFA-2162188 COQ5 methylates MDMQ10H2 IEA Canis familiaris 29033 R-CFA-2162193 https://reactome.org/PathwayBrowser/#/R-CFA-2162193 COQ3 methylates DHDB IEA Canis familiaris 29033 R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 29033 R-CFA-2172678 https://reactome.org/PathwayBrowser/#/R-CFA-2172678 PHF8 demethylates histone H4K20me1 IEA Canis familiaris 29033 R-CFA-265296 https://reactome.org/PathwayBrowser/#/R-CFA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Canis familiaris 29033 R-CFA-266050 https://reactome.org/PathwayBrowser/#/R-CFA-266050 LTA4 is converted to LTC4 by LTC4S IEA Canis familiaris 29033 R-CFA-266051 https://reactome.org/PathwayBrowser/#/R-CFA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Canis familiaris 29033 R-CFA-3222593 https://reactome.org/PathwayBrowser/#/R-CFA-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Canis familiaris 29033 R-CFA-389639 https://reactome.org/PathwayBrowser/#/R-CFA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Canis familiaris 29033 R-CFA-428259 https://reactome.org/PathwayBrowser/#/R-CFA-428259 DEGS1 dehydrogenates dihydroceramide IEA Canis familiaris 29033 R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 29033 R-CFA-435171 https://reactome.org/PathwayBrowser/#/R-CFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Canis familiaris 29033 R-CFA-435349 https://reactome.org/PathwayBrowser/#/R-CFA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Canis familiaris 29033 R-CFA-442368 https://reactome.org/PathwayBrowser/#/R-CFA-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Canis familiaris 29033 R-CFA-5164399 https://reactome.org/PathwayBrowser/#/R-CFA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Canis familiaris 29033 R-CFA-5678327 https://reactome.org/PathwayBrowser/#/R-CFA-5678327 MIOX oxidises Ins to GlcA IEA Canis familiaris 29033 R-CFA-5690873 https://reactome.org/PathwayBrowser/#/R-CFA-5690873 ACO1 binds 4Fe-4S IEA Canis familiaris 29033 R-CFA-5691107 https://reactome.org/PathwayBrowser/#/R-CFA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Canis familiaris 29033 R-CFA-5693761 https://reactome.org/PathwayBrowser/#/R-CFA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Canis familiaris 29033 R-CFA-6814153 https://reactome.org/PathwayBrowser/#/R-CFA-6814153 ADO oxidises 2AET to HTAU IEA Canis familiaris 29033 R-CFA-71118 https://reactome.org/PathwayBrowser/#/R-CFA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Canis familiaris 29033 R-CFA-71163 https://reactome.org/PathwayBrowser/#/R-CFA-71163 HPD dioxygenates HPP IEA Canis familiaris 29033 R-CFA-71164 https://reactome.org/PathwayBrowser/#/R-CFA-71164 HGD dioxygenates homogentisate IEA Canis familiaris 29033 R-CFA-71218 https://reactome.org/PathwayBrowser/#/R-CFA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Canis familiaris 29033 R-CFA-71241 https://reactome.org/PathwayBrowser/#/R-CFA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Canis familiaris 29033 R-CFA-71261 https://reactome.org/PathwayBrowser/#/R-CFA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Canis familiaris 29033 R-CFA-71303 https://reactome.org/PathwayBrowser/#/R-CFA-71303 RPE dimers isomerise RU5P to XY5P IEA Canis familiaris 29033 R-CFA-73815 https://reactome.org/PathwayBrowser/#/R-CFA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Canis familiaris 29033 R-CFA-8857692 https://reactome.org/PathwayBrowser/#/R-CFA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Canis familiaris 29033 R-CFA-8948219 https://reactome.org/PathwayBrowser/#/R-CFA-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Canis familiaris 29033 R-CFA-8948222 https://reactome.org/PathwayBrowser/#/R-CFA-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Canis familiaris 29033 R-CFA-8948224 https://reactome.org/PathwayBrowser/#/R-CFA-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Canis familiaris 29033 R-CFA-8948232 https://reactome.org/PathwayBrowser/#/R-CFA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Canis familiaris 29033 R-CFA-8979071 https://reactome.org/PathwayBrowser/#/R-CFA-8979071 KDM6B binds iron IEA Canis familiaris 29033 R-CFA-9020274 https://reactome.org/PathwayBrowser/#/R-CFA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Canis familiaris 29033 R-CFA-9024983 https://reactome.org/PathwayBrowser/#/R-CFA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Canis familiaris 29033 R-CFA-9025957 https://reactome.org/PathwayBrowser/#/R-CFA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Canis familiaris 29033 R-CFA-9026006 https://reactome.org/PathwayBrowser/#/R-CFA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Canis familiaris 29033 R-CFA-9026007 https://reactome.org/PathwayBrowser/#/R-CFA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Canis familiaris 29033 R-CFA-904830 https://reactome.org/PathwayBrowser/#/R-CFA-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Canis familiaris 29033 R-CFA-917805 https://reactome.org/PathwayBrowser/#/R-CFA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Canis familiaris 29033 R-CFA-917811 https://reactome.org/PathwayBrowser/#/R-CFA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Canis familiaris 29033 R-CFA-917891 https://reactome.org/PathwayBrowser/#/R-CFA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Canis familiaris 29033 R-CFA-917933 https://reactome.org/PathwayBrowser/#/R-CFA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Canis familiaris 29033 R-CFA-917936 https://reactome.org/PathwayBrowser/#/R-CFA-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Canis familiaris 29033 R-CFA-9629578 https://reactome.org/PathwayBrowser/#/R-CFA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Canis familiaris 29033 R-CFA-9629591 https://reactome.org/PathwayBrowser/#/R-CFA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Canis familiaris 29033 R-CFA-9629869 https://reactome.org/PathwayBrowser/#/R-CFA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Canis familiaris 29033 R-CFA-9629888 https://reactome.org/PathwayBrowser/#/R-CFA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Canis familiaris 29033 R-CFA-9629946 https://reactome.org/PathwayBrowser/#/R-CFA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Canis familiaris 29033 R-CFA-9630022 https://reactome.org/PathwayBrowser/#/R-CFA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Canis familiaris 29033 R-CFA-9630769 https://reactome.org/PathwayBrowser/#/R-CFA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Canis familiaris 29033 R-CFA-9630967 https://reactome.org/PathwayBrowser/#/R-CFA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Canis familiaris 29033 R-CFA-9630993 https://reactome.org/PathwayBrowser/#/R-CFA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Canis familiaris 29033 R-CFA-9707186 https://reactome.org/PathwayBrowser/#/R-CFA-9707186 ALOX5 binds ALOX5 inhibitors IEA Canis familiaris 29033 R-CFA-975635 https://reactome.org/PathwayBrowser/#/R-CFA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Canis familiaris 29033 R-CFA-9854368 https://reactome.org/PathwayBrowser/#/R-CFA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Canis familiaris 29033 R-CFA-9854405 https://reactome.org/PathwayBrowser/#/R-CFA-9854405 Frataxin transfers Fe2+ to ACO2 IEA Canis familiaris 29033 R-DDI-1237119 https://reactome.org/PathwayBrowser/#/R-DDI-1237119 Acireductone is oxidized to MOB IEA Dictyostelium discoideum 29033 R-DDI-1362408 https://reactome.org/PathwayBrowser/#/R-DDI-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Dictyostelium discoideum 29033 R-DDI-1362416 https://reactome.org/PathwayBrowser/#/R-DDI-1362416 Frataxin binds iron IEA Dictyostelium discoideum 29033 R-DDI-1614645 https://reactome.org/PathwayBrowser/#/R-DDI-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Dictyostelium discoideum 29033 R-DDI-189465 https://reactome.org/PathwayBrowser/#/R-DDI-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Dictyostelium discoideum 29033 R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 29033 R-DDI-199803 https://reactome.org/PathwayBrowser/#/R-DDI-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Dictyostelium discoideum 29033 R-DDI-204662 https://reactome.org/PathwayBrowser/#/R-DDI-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Dictyostelium discoideum 29033 R-DDI-209823 https://reactome.org/PathwayBrowser/#/R-DDI-209823 Tyrosine is hydroxylated to dopa IEA Dictyostelium discoideum 29033 R-DDI-209828 https://reactome.org/PathwayBrowser/#/R-DDI-209828 Tryptophan is hydroxylated IEA Dictyostelium discoideum 29033 R-DDI-2161768 https://reactome.org/PathwayBrowser/#/R-DDI-2161768 EXA4 is converted to EXC4 by LTC4S IEA Dictyostelium discoideum 29033 R-DDI-2161775 https://reactome.org/PathwayBrowser/#/R-DDI-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Dictyostelium discoideum 29033 R-DDI-2161794 https://reactome.org/PathwayBrowser/#/R-DDI-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Dictyostelium discoideum 29033 R-DDI-2161907 https://reactome.org/PathwayBrowser/#/R-DDI-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Dictyostelium discoideum 29033 R-DDI-2161917 https://reactome.org/PathwayBrowser/#/R-DDI-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Dictyostelium discoideum 29033 R-DDI-2161948 https://reactome.org/PathwayBrowser/#/R-DDI-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Dictyostelium discoideum 29033 R-DDI-2161950 https://reactome.org/PathwayBrowser/#/R-DDI-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Dictyostelium discoideum 29033 R-DDI-2161964 https://reactome.org/PathwayBrowser/#/R-DDI-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Dictyostelium discoideum 29033 R-DDI-2162002 https://reactome.org/PathwayBrowser/#/R-DDI-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Dictyostelium discoideum 29033 R-DDI-2162019 https://reactome.org/PathwayBrowser/#/R-DDI-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Dictyostelium discoideum 29033 R-DDI-2162186 https://reactome.org/PathwayBrowser/#/R-DDI-2162186 COQ3 methylates DeMQ10H2 IEA Dictyostelium discoideum 29033 R-DDI-2162188 https://reactome.org/PathwayBrowser/#/R-DDI-2162188 COQ5 methylates MDMQ10H2 IEA Dictyostelium discoideum 29033 R-DDI-2162193 https://reactome.org/PathwayBrowser/#/R-DDI-2162193 COQ3 methylates DHDB IEA Dictyostelium discoideum 29033 R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 29033 R-DDI-2172678 https://reactome.org/PathwayBrowser/#/R-DDI-2172678 PHF8 demethylates histone H4K20me1 IEA Dictyostelium discoideum 29033 R-DDI-265296 https://reactome.org/PathwayBrowser/#/R-DDI-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Dictyostelium discoideum 29033 R-DDI-266050 https://reactome.org/PathwayBrowser/#/R-DDI-266050 LTA4 is converted to LTC4 by LTC4S IEA Dictyostelium discoideum 29033 R-DDI-266051 https://reactome.org/PathwayBrowser/#/R-DDI-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Dictyostelium discoideum 29033 R-DDI-3222593 https://reactome.org/PathwayBrowser/#/R-DDI-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Dictyostelium discoideum 29033 R-DDI-389639 https://reactome.org/PathwayBrowser/#/R-DDI-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Dictyostelium discoideum 29033 R-DDI-428259 https://reactome.org/PathwayBrowser/#/R-DDI-428259 DEGS1 dehydrogenates dihydroceramide IEA Dictyostelium discoideum 29033 R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 29033 R-DDI-435171 https://reactome.org/PathwayBrowser/#/R-DDI-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Dictyostelium discoideum 29033 R-DDI-435349 https://reactome.org/PathwayBrowser/#/R-DDI-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Dictyostelium discoideum 29033 R-DDI-5678327 https://reactome.org/PathwayBrowser/#/R-DDI-5678327 MIOX oxidises Ins to GlcA IEA Dictyostelium discoideum 29033 R-DDI-5690873 https://reactome.org/PathwayBrowser/#/R-DDI-5690873 ACO1 binds 4Fe-4S IEA Dictyostelium discoideum 29033 R-DDI-5693761 https://reactome.org/PathwayBrowser/#/R-DDI-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Dictyostelium discoideum 29033 R-DDI-6814153 https://reactome.org/PathwayBrowser/#/R-DDI-6814153 ADO oxidises 2AET to HTAU IEA Dictyostelium discoideum 29033 R-DDI-71118 https://reactome.org/PathwayBrowser/#/R-DDI-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Dictyostelium discoideum 29033 R-DDI-71163 https://reactome.org/PathwayBrowser/#/R-DDI-71163 HPD dioxygenates HPP IEA Dictyostelium discoideum 29033 R-DDI-71164 https://reactome.org/PathwayBrowser/#/R-DDI-71164 HGD dioxygenates homogentisate IEA Dictyostelium discoideum 29033 R-DDI-71218 https://reactome.org/PathwayBrowser/#/R-DDI-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Dictyostelium discoideum 29033 R-DDI-71303 https://reactome.org/PathwayBrowser/#/R-DDI-71303 RPE dimers isomerise RU5P to XY5P IEA Dictyostelium discoideum 29033 R-DDI-8979071 https://reactome.org/PathwayBrowser/#/R-DDI-8979071 KDM6B binds iron IEA Dictyostelium discoideum 29033 R-DDI-9020274 https://reactome.org/PathwayBrowser/#/R-DDI-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Dictyostelium discoideum 29033 R-DDI-9024983 https://reactome.org/PathwayBrowser/#/R-DDI-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Dictyostelium discoideum 29033 R-DDI-9025957 https://reactome.org/PathwayBrowser/#/R-DDI-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Dictyostelium discoideum 29033 R-DDI-9026006 https://reactome.org/PathwayBrowser/#/R-DDI-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Dictyostelium discoideum 29033 R-DDI-9026007 https://reactome.org/PathwayBrowser/#/R-DDI-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Dictyostelium discoideum 29033 R-DDI-917936 https://reactome.org/PathwayBrowser/#/R-DDI-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Dictyostelium discoideum 29033 R-DDI-9629578 https://reactome.org/PathwayBrowser/#/R-DDI-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Dictyostelium discoideum 29033 R-DDI-9629591 https://reactome.org/PathwayBrowser/#/R-DDI-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Dictyostelium discoideum 29033 R-DDI-9629869 https://reactome.org/PathwayBrowser/#/R-DDI-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Dictyostelium discoideum 29033 R-DDI-9630993 https://reactome.org/PathwayBrowser/#/R-DDI-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Dictyostelium discoideum 29033 R-DDI-9707186 https://reactome.org/PathwayBrowser/#/R-DDI-9707186 ALOX5 binds ALOX5 inhibitors IEA Dictyostelium discoideum 29033 R-DDI-9854368 https://reactome.org/PathwayBrowser/#/R-DDI-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Dictyostelium discoideum 29033 R-DDI-9854405 https://reactome.org/PathwayBrowser/#/R-DDI-9854405 Frataxin transfers Fe2+ to ACO2 IEA Dictyostelium discoideum 29033 R-DME-111285 https://reactome.org/PathwayBrowser/#/R-DME-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Drosophila melanogaster 29033 R-DME-111289 https://reactome.org/PathwayBrowser/#/R-DME-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Drosophila melanogaster 29033 R-DME-1234159 https://reactome.org/PathwayBrowser/#/R-DME-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Drosophila melanogaster 29033 R-DME-1234163 https://reactome.org/PathwayBrowser/#/R-DME-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Drosophila melanogaster 29033 R-DME-1234165 https://reactome.org/PathwayBrowser/#/R-DME-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 29033 R-DME-1234173 https://reactome.org/PathwayBrowser/#/R-DME-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 29033 R-DME-1234177 https://reactome.org/PathwayBrowser/#/R-DME-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 29033 R-DME-1234181 https://reactome.org/PathwayBrowser/#/R-DME-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 29033 R-DME-1234183 https://reactome.org/PathwayBrowser/#/R-DME-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Drosophila melanogaster 29033 R-DME-1237119 https://reactome.org/PathwayBrowser/#/R-DME-1237119 Acireductone is oxidized to MOB IEA Drosophila melanogaster 29033 R-DME-1362408 https://reactome.org/PathwayBrowser/#/R-DME-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Drosophila melanogaster 29033 R-DME-1362416 https://reactome.org/PathwayBrowser/#/R-DME-1362416 Frataxin binds iron IEA Drosophila melanogaster 29033 R-DME-1562626 https://reactome.org/PathwayBrowser/#/R-DME-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Drosophila melanogaster 29033 R-DME-1614645 https://reactome.org/PathwayBrowser/#/R-DME-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Drosophila melanogaster 29033 R-DME-189398 https://reactome.org/PathwayBrowser/#/R-DME-189398 HMOX1 dimer, HMOX2 cleave heme IEA Drosophila melanogaster 29033 R-DME-189465 https://reactome.org/PathwayBrowser/#/R-DME-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Drosophila melanogaster 29033 R-DME-1981104 https://reactome.org/PathwayBrowser/#/R-DME-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Drosophila melanogaster 29033 R-DME-1981128 https://reactome.org/PathwayBrowser/#/R-DME-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Drosophila melanogaster 29033 R-DME-1981157 https://reactome.org/PathwayBrowser/#/R-DME-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Drosophila melanogaster 29033 R-DME-199803 https://reactome.org/PathwayBrowser/#/R-DME-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Drosophila melanogaster 29033 R-DME-204662 https://reactome.org/PathwayBrowser/#/R-DME-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Drosophila melanogaster 29033 R-DME-209823 https://reactome.org/PathwayBrowser/#/R-DME-209823 Tyrosine is hydroxylated to dopa IEA Drosophila melanogaster 29033 R-DME-209828 https://reactome.org/PathwayBrowser/#/R-DME-209828 Tryptophan is hydroxylated IEA Drosophila melanogaster 29033 R-DME-2162186 https://reactome.org/PathwayBrowser/#/R-DME-2162186 COQ3 methylates DeMQ10H2 IEA Drosophila melanogaster 29033 R-DME-2162188 https://reactome.org/PathwayBrowser/#/R-DME-2162188 COQ5 methylates MDMQ10H2 IEA Drosophila melanogaster 29033 R-DME-2162193 https://reactome.org/PathwayBrowser/#/R-DME-2162193 COQ3 methylates DHDB IEA Drosophila melanogaster 29033 R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 29033 R-DME-2172678 https://reactome.org/PathwayBrowser/#/R-DME-2172678 PHF8 demethylates histone H4K20me1 IEA Drosophila melanogaster 29033 R-DME-2301205 https://reactome.org/PathwayBrowser/#/R-DME-2301205 SETD8 monomethylates histone H4 IEA Drosophila melanogaster 29033 R-DME-3222593 https://reactome.org/PathwayBrowser/#/R-DME-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Drosophila melanogaster 29033 R-DME-428259 https://reactome.org/PathwayBrowser/#/R-DME-428259 DEGS1 dehydrogenates dihydroceramide IEA Drosophila melanogaster 29033 R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 29033 R-DME-435171 https://reactome.org/PathwayBrowser/#/R-DME-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Drosophila melanogaster 29033 R-DME-435349 https://reactome.org/PathwayBrowser/#/R-DME-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Drosophila melanogaster 29033 R-DME-5164399 https://reactome.org/PathwayBrowser/#/R-DME-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Drosophila melanogaster 29033 R-DME-5678327 https://reactome.org/PathwayBrowser/#/R-DME-5678327 MIOX oxidises Ins to GlcA IEA Drosophila melanogaster 29033 R-DME-5690873 https://reactome.org/PathwayBrowser/#/R-DME-5690873 ACO1 binds 4Fe-4S IEA Drosophila melanogaster 29033 R-DME-5691107 https://reactome.org/PathwayBrowser/#/R-DME-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Drosophila melanogaster 29033 R-DME-5693761 https://reactome.org/PathwayBrowser/#/R-DME-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Drosophila melanogaster 29033 R-DME-6814153 https://reactome.org/PathwayBrowser/#/R-DME-6814153 ADO oxidises 2AET to HTAU IEA Drosophila melanogaster 29033 R-DME-71118 https://reactome.org/PathwayBrowser/#/R-DME-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Drosophila melanogaster 29033 R-DME-71163 https://reactome.org/PathwayBrowser/#/R-DME-71163 HPD dioxygenates HPP IEA Drosophila melanogaster 29033 R-DME-71164 https://reactome.org/PathwayBrowser/#/R-DME-71164 HGD dioxygenates homogentisate IEA Drosophila melanogaster 29033 R-DME-71241 https://reactome.org/PathwayBrowser/#/R-DME-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Drosophila melanogaster 29033 R-DME-71261 https://reactome.org/PathwayBrowser/#/R-DME-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Drosophila melanogaster 29033 R-DME-71303 https://reactome.org/PathwayBrowser/#/R-DME-71303 RPE dimers isomerise RU5P to XY5P IEA Drosophila melanogaster 29033 R-DME-73815 https://reactome.org/PathwayBrowser/#/R-DME-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Drosophila melanogaster 29033 R-DME-8979071 https://reactome.org/PathwayBrowser/#/R-DME-8979071 KDM6B binds iron IEA Drosophila melanogaster 29033 R-DME-917805 https://reactome.org/PathwayBrowser/#/R-DME-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Drosophila melanogaster 29033 R-DME-917936 https://reactome.org/PathwayBrowser/#/R-DME-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Drosophila melanogaster 29033 R-DME-9629578 https://reactome.org/PathwayBrowser/#/R-DME-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Drosophila melanogaster 29033 R-DME-9629591 https://reactome.org/PathwayBrowser/#/R-DME-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Drosophila melanogaster 29033 R-DME-9629869 https://reactome.org/PathwayBrowser/#/R-DME-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Drosophila melanogaster 29033 R-DME-9629888 https://reactome.org/PathwayBrowser/#/R-DME-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Drosophila melanogaster 29033 R-DME-9629946 https://reactome.org/PathwayBrowser/#/R-DME-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Drosophila melanogaster 29033 R-DME-9630022 https://reactome.org/PathwayBrowser/#/R-DME-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Drosophila melanogaster 29033 R-DME-9630769 https://reactome.org/PathwayBrowser/#/R-DME-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Drosophila melanogaster 29033 R-DME-9630993 https://reactome.org/PathwayBrowser/#/R-DME-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Drosophila melanogaster 29033 R-DME-975635 https://reactome.org/PathwayBrowser/#/R-DME-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Drosophila melanogaster 29033 R-DME-9854368 https://reactome.org/PathwayBrowser/#/R-DME-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Drosophila melanogaster 29033 R-DME-9854405 https://reactome.org/PathwayBrowser/#/R-DME-9854405 Frataxin transfers Fe2+ to ACO2 IEA Drosophila melanogaster 29033 R-DRE-111285 https://reactome.org/PathwayBrowser/#/R-DRE-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Danio rerio 29033 R-DRE-111289 https://reactome.org/PathwayBrowser/#/R-DRE-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Danio rerio 29033 R-DRE-1234164 https://reactome.org/PathwayBrowser/#/R-DRE-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Danio rerio 29033 R-DRE-1234165 https://reactome.org/PathwayBrowser/#/R-DRE-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Danio rerio 29033 R-DRE-1234181 https://reactome.org/PathwayBrowser/#/R-DRE-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Danio rerio 29033 R-DRE-1237119 https://reactome.org/PathwayBrowser/#/R-DRE-1237119 Acireductone is oxidized to MOB IEA Danio rerio 29033 R-DRE-1362408 https://reactome.org/PathwayBrowser/#/R-DRE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Danio rerio 29033 R-DRE-1362416 https://reactome.org/PathwayBrowser/#/R-DRE-1362416 Frataxin binds iron IEA Danio rerio 29033 R-DRE-1562626 https://reactome.org/PathwayBrowser/#/R-DRE-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Danio rerio 29033 R-DRE-1614645 https://reactome.org/PathwayBrowser/#/R-DRE-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Danio rerio 29033 R-DRE-1650808 https://reactome.org/PathwayBrowser/#/R-DRE-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Danio rerio 29033 R-DRE-189398 https://reactome.org/PathwayBrowser/#/R-DRE-189398 HMOX1 dimer, HMOX2 cleave heme IEA Danio rerio 29033 R-DRE-189465 https://reactome.org/PathwayBrowser/#/R-DRE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Danio rerio 29033 R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 29033 R-DRE-1981104 https://reactome.org/PathwayBrowser/#/R-DRE-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Danio rerio 29033 R-DRE-1981128 https://reactome.org/PathwayBrowser/#/R-DRE-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Danio rerio 29033 R-DRE-1981157 https://reactome.org/PathwayBrowser/#/R-DRE-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Danio rerio 29033 R-DRE-199803 https://reactome.org/PathwayBrowser/#/R-DRE-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Danio rerio 29033 R-DRE-204662 https://reactome.org/PathwayBrowser/#/R-DRE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Danio rerio 29033 R-DRE-209823 https://reactome.org/PathwayBrowser/#/R-DRE-209823 Tyrosine is hydroxylated to dopa IEA Danio rerio 29033 R-DRE-209828 https://reactome.org/PathwayBrowser/#/R-DRE-209828 Tryptophan is hydroxylated IEA Danio rerio 29033 R-DRE-2161775 https://reactome.org/PathwayBrowser/#/R-DRE-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Danio rerio 29033 R-DRE-2161794 https://reactome.org/PathwayBrowser/#/R-DRE-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Danio rerio 29033 R-DRE-2161948 https://reactome.org/PathwayBrowser/#/R-DRE-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Danio rerio 29033 R-DRE-2161950 https://reactome.org/PathwayBrowser/#/R-DRE-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Danio rerio 29033 R-DRE-2161964 https://reactome.org/PathwayBrowser/#/R-DRE-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Danio rerio 29033 R-DRE-2162002 https://reactome.org/PathwayBrowser/#/R-DRE-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Danio rerio 29033 R-DRE-2162019 https://reactome.org/PathwayBrowser/#/R-DRE-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Danio rerio 29033 R-DRE-2162186 https://reactome.org/PathwayBrowser/#/R-DRE-2162186 COQ3 methylates DeMQ10H2 IEA Danio rerio 29033 R-DRE-2162188 https://reactome.org/PathwayBrowser/#/R-DRE-2162188 COQ5 methylates MDMQ10H2 IEA Danio rerio 29033 R-DRE-2162193 https://reactome.org/PathwayBrowser/#/R-DRE-2162193 COQ3 methylates DHDB IEA Danio rerio 29033 R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 29033 R-DRE-2172678 https://reactome.org/PathwayBrowser/#/R-DRE-2172678 PHF8 demethylates histone H4K20me1 IEA Danio rerio 29033 R-DRE-2245218 https://reactome.org/PathwayBrowser/#/R-DRE-2245218 CDK1 phosphorylates PHF8 IEA Danio rerio 29033 R-DRE-2301205 https://reactome.org/PathwayBrowser/#/R-DRE-2301205 SETD8 monomethylates histone H4 IEA Danio rerio 29033 R-DRE-389639 https://reactome.org/PathwayBrowser/#/R-DRE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Danio rerio 29033 R-DRE-428259 https://reactome.org/PathwayBrowser/#/R-DRE-428259 DEGS1 dehydrogenates dihydroceramide IEA Danio rerio 29033 R-DRE-429016 https://reactome.org/PathwayBrowser/#/R-DRE-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Danio rerio 29033 R-DRE-435171 https://reactome.org/PathwayBrowser/#/R-DRE-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Danio rerio 29033 R-DRE-435349 https://reactome.org/PathwayBrowser/#/R-DRE-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Danio rerio 29033 R-DRE-5164399 https://reactome.org/PathwayBrowser/#/R-DRE-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Danio rerio 29033 R-DRE-5678327 https://reactome.org/PathwayBrowser/#/R-DRE-5678327 MIOX oxidises Ins to GlcA IEA Danio rerio 29033 R-DRE-5690873 https://reactome.org/PathwayBrowser/#/R-DRE-5690873 ACO1 binds 4Fe-4S IEA Danio rerio 29033 R-DRE-5691107 https://reactome.org/PathwayBrowser/#/R-DRE-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Danio rerio 29033 R-DRE-6814153 https://reactome.org/PathwayBrowser/#/R-DRE-6814153 ADO oxidises 2AET to HTAU IEA Danio rerio 29033 R-DRE-71118 https://reactome.org/PathwayBrowser/#/R-DRE-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Danio rerio 29033 R-DRE-71163 https://reactome.org/PathwayBrowser/#/R-DRE-71163 HPD dioxygenates HPP IEA Danio rerio 29033 R-DRE-71164 https://reactome.org/PathwayBrowser/#/R-DRE-71164 HGD dioxygenates homogentisate IEA Danio rerio 29033 R-DRE-71218 https://reactome.org/PathwayBrowser/#/R-DRE-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Danio rerio 29033 R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio 29033 R-DRE-71303 https://reactome.org/PathwayBrowser/#/R-DRE-71303 RPE dimers isomerise RU5P to XY5P IEA Danio rerio 29033 R-DRE-73815 https://reactome.org/PathwayBrowser/#/R-DRE-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Danio rerio 29033 R-DRE-8857692 https://reactome.org/PathwayBrowser/#/R-DRE-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Danio rerio 29033 R-DRE-8948219 https://reactome.org/PathwayBrowser/#/R-DRE-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Danio rerio 29033 R-DRE-8948222 https://reactome.org/PathwayBrowser/#/R-DRE-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Danio rerio 29033 R-DRE-8948224 https://reactome.org/PathwayBrowser/#/R-DRE-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Danio rerio 29033 R-DRE-8948232 https://reactome.org/PathwayBrowser/#/R-DRE-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Danio rerio 29033 R-DRE-9020274 https://reactome.org/PathwayBrowser/#/R-DRE-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Danio rerio 29033 R-DRE-9024983 https://reactome.org/PathwayBrowser/#/R-DRE-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Danio rerio 29033 R-DRE-9025957 https://reactome.org/PathwayBrowser/#/R-DRE-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Danio rerio 29033 R-DRE-9026006 https://reactome.org/PathwayBrowser/#/R-DRE-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Danio rerio 29033 R-DRE-9026007 https://reactome.org/PathwayBrowser/#/R-DRE-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Danio rerio 29033 R-DRE-904830 https://reactome.org/PathwayBrowser/#/R-DRE-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Danio rerio 29033 R-DRE-917805 https://reactome.org/PathwayBrowser/#/R-DRE-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Danio rerio 29033 R-DRE-917891 https://reactome.org/PathwayBrowser/#/R-DRE-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Danio rerio 29033 R-DRE-917936 https://reactome.org/PathwayBrowser/#/R-DRE-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Danio rerio 29033 R-DRE-9629591 https://reactome.org/PathwayBrowser/#/R-DRE-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Danio rerio 29033 R-DRE-9629869 https://reactome.org/PathwayBrowser/#/R-DRE-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Danio rerio 29033 R-DRE-9629946 https://reactome.org/PathwayBrowser/#/R-DRE-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Danio rerio 29033 R-DRE-9630993 https://reactome.org/PathwayBrowser/#/R-DRE-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Danio rerio 29033 R-DRE-975635 https://reactome.org/PathwayBrowser/#/R-DRE-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Danio rerio 29033 R-DRE-9854368 https://reactome.org/PathwayBrowser/#/R-DRE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Danio rerio 29033 R-DRE-9854405 https://reactome.org/PathwayBrowser/#/R-DRE-9854405 Frataxin transfers Fe2+ to ACO2 IEA Danio rerio 29033 R-ECO-1222667 https://reactome.org/PathwayBrowser/#/R-ECO-1222667 Iron is reduced and separates from enterobactin TAS Escherichia coli 29033 R-GGA-111285 https://reactome.org/PathwayBrowser/#/R-GGA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Gallus gallus 29033 R-GGA-111289 https://reactome.org/PathwayBrowser/#/R-GGA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Gallus gallus 29033 R-GGA-1234163 https://reactome.org/PathwayBrowser/#/R-GGA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Gallus gallus 29033 R-GGA-1234164 https://reactome.org/PathwayBrowser/#/R-GGA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Gallus gallus 29033 R-GGA-1234165 https://reactome.org/PathwayBrowser/#/R-GGA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 29033 R-GGA-1234173 https://reactome.org/PathwayBrowser/#/R-GGA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 29033 R-GGA-1234177 https://reactome.org/PathwayBrowser/#/R-GGA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 29033 R-GGA-1234181 https://reactome.org/PathwayBrowser/#/R-GGA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 29033 R-GGA-1234183 https://reactome.org/PathwayBrowser/#/R-GGA-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Gallus gallus 29033 R-GGA-1237119 https://reactome.org/PathwayBrowser/#/R-GGA-1237119 Acireductone is oxidized to MOB IEA Gallus gallus 29033 R-GGA-1362408 https://reactome.org/PathwayBrowser/#/R-GGA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Gallus gallus 29033 R-GGA-1362416 https://reactome.org/PathwayBrowser/#/R-GGA-1362416 Frataxin binds iron IEA Gallus gallus 29033 R-GGA-1562626 https://reactome.org/PathwayBrowser/#/R-GGA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Gallus gallus 29033 R-GGA-1614645 https://reactome.org/PathwayBrowser/#/R-GGA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Gallus gallus 29033 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus 29033 R-GGA-189398 https://reactome.org/PathwayBrowser/#/R-GGA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Gallus gallus 29033 R-GGA-189465 https://reactome.org/PathwayBrowser/#/R-GGA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Gallus gallus 29033 R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 29033 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus 29033 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus 29033 R-GGA-199803 https://reactome.org/PathwayBrowser/#/R-GGA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Gallus gallus 29033 R-GGA-204662 https://reactome.org/PathwayBrowser/#/R-GGA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Gallus gallus 29033 R-GGA-209823 https://reactome.org/PathwayBrowser/#/R-GGA-209823 Tyrosine is hydroxylated to dopa IEA Gallus gallus 29033 R-GGA-209828 https://reactome.org/PathwayBrowser/#/R-GGA-209828 Tryptophan is hydroxylated IEA Gallus gallus 29033 R-GGA-2161768 https://reactome.org/PathwayBrowser/#/R-GGA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Gallus gallus 29033 R-GGA-2161907 https://reactome.org/PathwayBrowser/#/R-GGA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Gallus gallus 29033 R-GGA-2161917 https://reactome.org/PathwayBrowser/#/R-GGA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Gallus gallus 29033 R-GGA-2161950 https://reactome.org/PathwayBrowser/#/R-GGA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Gallus gallus 29033 R-GGA-2162002 https://reactome.org/PathwayBrowser/#/R-GGA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Gallus gallus 29033 R-GGA-2162186 https://reactome.org/PathwayBrowser/#/R-GGA-2162186 COQ3 methylates DeMQ10H2 IEA Gallus gallus 29033 R-GGA-2162188 https://reactome.org/PathwayBrowser/#/R-GGA-2162188 COQ5 methylates MDMQ10H2 IEA Gallus gallus 29033 R-GGA-2162193 https://reactome.org/PathwayBrowser/#/R-GGA-2162193 COQ3 methylates DHDB IEA Gallus gallus 29033 R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 29033 R-GGA-2172678 https://reactome.org/PathwayBrowser/#/R-GGA-2172678 PHF8 demethylates histone H4K20me1 IEA Gallus gallus 29033 R-GGA-2301205 https://reactome.org/PathwayBrowser/#/R-GGA-2301205 SETD8 monomethylates histone H4 IEA Gallus gallus 29033 R-GGA-265296 https://reactome.org/PathwayBrowser/#/R-GGA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Gallus gallus 29033 R-GGA-266050 https://reactome.org/PathwayBrowser/#/R-GGA-266050 LTA4 is converted to LTC4 by LTC4S IEA Gallus gallus 29033 R-GGA-266051 https://reactome.org/PathwayBrowser/#/R-GGA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Gallus gallus 29033 R-GGA-389639 https://reactome.org/PathwayBrowser/#/R-GGA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Gallus gallus 29033 R-GGA-421447 https://reactome.org/PathwayBrowser/#/R-GGA-421447 protoporphyrin IX + Fe++ => heme + 2 H+ TAS Gallus gallus 29033 R-GGA-428259 https://reactome.org/PathwayBrowser/#/R-GGA-428259 DEGS1 dehydrogenates dihydroceramide IEA Gallus gallus 29033 R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 29033 R-GGA-429016 https://reactome.org/PathwayBrowser/#/R-GGA-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Gallus gallus 29033 R-GGA-435171 https://reactome.org/PathwayBrowser/#/R-GGA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Gallus gallus 29033 R-GGA-435349 https://reactome.org/PathwayBrowser/#/R-GGA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Gallus gallus 29033 R-GGA-442368 https://reactome.org/PathwayBrowser/#/R-GGA-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Gallus gallus 29033 R-GGA-5164399 https://reactome.org/PathwayBrowser/#/R-GGA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Gallus gallus 29033 R-GGA-5678327 https://reactome.org/PathwayBrowser/#/R-GGA-5678327 MIOX oxidises Ins to GlcA IEA Gallus gallus 29033 R-GGA-5690873 https://reactome.org/PathwayBrowser/#/R-GGA-5690873 ACO1 binds 4Fe-4S IEA Gallus gallus 29033 R-GGA-5691107 https://reactome.org/PathwayBrowser/#/R-GGA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Gallus gallus 29033 R-GGA-5693761 https://reactome.org/PathwayBrowser/#/R-GGA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Gallus gallus 29033 R-GGA-71118 https://reactome.org/PathwayBrowser/#/R-GGA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Gallus gallus 29033 R-GGA-71163 https://reactome.org/PathwayBrowser/#/R-GGA-71163 HPD dioxygenates HPP IEA Gallus gallus 29033 R-GGA-71164 https://reactome.org/PathwayBrowser/#/R-GGA-71164 HGD dioxygenates homogentisate IEA Gallus gallus 29033 R-GGA-71218 https://reactome.org/PathwayBrowser/#/R-GGA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Gallus gallus 29033 R-GGA-71241 https://reactome.org/PathwayBrowser/#/R-GGA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Gallus gallus 29033 R-GGA-71261 https://reactome.org/PathwayBrowser/#/R-GGA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Gallus gallus 29033 R-GGA-71303 https://reactome.org/PathwayBrowser/#/R-GGA-71303 RPE dimers isomerise RU5P to XY5P IEA Gallus gallus 29033 R-GGA-73815 https://reactome.org/PathwayBrowser/#/R-GGA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Gallus gallus 29033 R-GGA-8857692 https://reactome.org/PathwayBrowser/#/R-GGA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Gallus gallus 29033 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus 29033 R-GGA-904830 https://reactome.org/PathwayBrowser/#/R-GGA-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Gallus gallus 29033 R-GGA-917805 https://reactome.org/PathwayBrowser/#/R-GGA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Gallus gallus 29033 R-GGA-917811 https://reactome.org/PathwayBrowser/#/R-GGA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Gallus gallus 29033 R-GGA-917891 https://reactome.org/PathwayBrowser/#/R-GGA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Gallus gallus 29033 R-GGA-917933 https://reactome.org/PathwayBrowser/#/R-GGA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Gallus gallus 29033 R-GGA-917936 https://reactome.org/PathwayBrowser/#/R-GGA-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Gallus gallus 29033 R-GGA-9629578 https://reactome.org/PathwayBrowser/#/R-GGA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Gallus gallus 29033 R-GGA-9629591 https://reactome.org/PathwayBrowser/#/R-GGA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Gallus gallus 29033 R-GGA-9629869 https://reactome.org/PathwayBrowser/#/R-GGA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Gallus gallus 29033 R-GGA-9629946 https://reactome.org/PathwayBrowser/#/R-GGA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Gallus gallus 29033 R-GGA-9630022 https://reactome.org/PathwayBrowser/#/R-GGA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Gallus gallus 29033 R-GGA-9630769 https://reactome.org/PathwayBrowser/#/R-GGA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Gallus gallus 29033 R-GGA-9630967 https://reactome.org/PathwayBrowser/#/R-GGA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Gallus gallus 29033 R-GGA-9630993 https://reactome.org/PathwayBrowser/#/R-GGA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Gallus gallus 29033 R-GGA-9707186 https://reactome.org/PathwayBrowser/#/R-GGA-9707186 ALOX5 binds ALOX5 inhibitors IEA Gallus gallus 29033 R-GGA-975635 https://reactome.org/PathwayBrowser/#/R-GGA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Gallus gallus 29033 R-GGA-9854368 https://reactome.org/PathwayBrowser/#/R-GGA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Gallus gallus 29033 R-GGA-9854405 https://reactome.org/PathwayBrowser/#/R-GGA-9854405 Frataxin transfers Fe2+ to ACO2 IEA Gallus gallus 29033 R-HSA-111285 https://reactome.org/PathwayBrowser/#/R-HSA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer TAS Homo sapiens 29033 R-HSA-111289 https://reactome.org/PathwayBrowser/#/R-HSA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer TAS Homo sapiens 29033 R-HSA-112118 https://reactome.org/PathwayBrowser/#/R-HSA-112118 Oxidative demethylation of 1-meA damaged DNA by ALKBH2 TAS Homo sapiens 29033 R-HSA-112120 https://reactome.org/PathwayBrowser/#/R-HSA-112120 Oxidative demethylation of 3-meC damaged DNA by ALKBH2 TAS Homo sapiens 29033 R-HSA-112121 https://reactome.org/PathwayBrowser/#/R-HSA-112121 Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 TAS Homo sapiens 29033 R-HSA-112123 https://reactome.org/PathwayBrowser/#/R-HSA-112123 Oxidative demethylation of 1-meA damaged DNA By ALKBH3 TAS Homo sapiens 29033 R-HSA-112124 https://reactome.org/PathwayBrowser/#/R-HSA-112124 Oxidative demethylation of 3-meC damaged DNA By ALKBH3 TAS Homo sapiens 29033 R-HSA-112125 https://reactome.org/PathwayBrowser/#/R-HSA-112125 Oxidative dealkylation of 1-EtA damaged DNA by ABH3 TAS Homo sapiens 29033 R-HSA-1222399 https://reactome.org/PathwayBrowser/#/R-HSA-1222399 Iron is reduced and separates from mycobactin IEA Homo sapiens 29033 R-HSA-1222462 https://reactome.org/PathwayBrowser/#/R-HSA-1222462 SodB reduces superoxide to H2O2 TAS Homo sapiens 29033 R-HSA-1234159 https://reactome.org/PathwayBrowser/#/R-HSA-1234159 Proteasome proteolyzes ub-HIF-alpha TAS Homo sapiens 29033 R-HSA-1234163 https://reactome.org/PathwayBrowser/#/R-HSA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha TAS Homo sapiens 29033 R-HSA-1234164 https://reactome.org/PathwayBrowser/#/R-HSA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) TAS Homo sapiens 29033 R-HSA-1234165 https://reactome.org/PathwayBrowser/#/R-HSA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 29033 R-HSA-1234166 https://reactome.org/PathwayBrowser/#/R-HSA-1234166 Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 29033 R-HSA-1234173 https://reactome.org/PathwayBrowser/#/R-HSA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 29033 R-HSA-1234177 https://reactome.org/PathwayBrowser/#/R-HSA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 29033 R-HSA-1234179 https://reactome.org/PathwayBrowser/#/R-HSA-1234179 Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 29033 R-HSA-1234181 https://reactome.org/PathwayBrowser/#/R-HSA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 29033 R-HSA-1234183 https://reactome.org/PathwayBrowser/#/R-HSA-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha TAS Homo sapiens 29033 R-HSA-1237119 https://reactome.org/PathwayBrowser/#/R-HSA-1237119 Acireductone is oxidized to MOB TAS Homo sapiens 29033 R-HSA-1362408 https://reactome.org/PathwayBrowser/#/R-HSA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster TAS Homo sapiens 29033 R-HSA-1362416 https://reactome.org/PathwayBrowser/#/R-HSA-1362416 Frataxin binds iron TAS Homo sapiens 29033 R-HSA-1362417 https://reactome.org/PathwayBrowser/#/R-HSA-1362417 Mitoferrin translocates iron from the mitochondrial intermembrane space to the mitochondrial matrix IEA Homo sapiens 29033 R-HSA-1497883 https://reactome.org/PathwayBrowser/#/R-HSA-1497883 Ferrous iron reduces the BH3 radical back to BH4 TAS Homo sapiens 29033 R-HSA-1562603 https://reactome.org/PathwayBrowser/#/R-HSA-1562603 BfrB stores iron TAS Homo sapiens 29033 R-HSA-1562604 https://reactome.org/PathwayBrowser/#/R-HSA-1562604 BfrA stores iron TAS Homo sapiens 29033 R-HSA-1562626 https://reactome.org/PathwayBrowser/#/R-HSA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) TAS Homo sapiens 29033 R-HSA-1614645 https://reactome.org/PathwayBrowser/#/R-HSA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine TAS Homo sapiens 29033 R-HSA-1650808 https://reactome.org/PathwayBrowser/#/R-HSA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines TAS Homo sapiens 29033 R-HSA-180038 https://reactome.org/PathwayBrowser/#/R-HSA-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function TAS Homo sapiens 29033 R-HSA-189398 https://reactome.org/PathwayBrowser/#/R-HSA-189398 HMOX1 dimer, HMOX2 cleave heme TAS Homo sapiens 29033 R-HSA-189465 https://reactome.org/PathwayBrowser/#/R-HSA-189465 FECH binds Fe2+ to PRIN9 to form heme TAS Homo sapiens 29033 R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 29033 R-HSA-1980233 https://reactome.org/PathwayBrowser/#/R-HSA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen TAS Homo sapiens 29033 R-HSA-1981104 https://reactome.org/PathwayBrowser/#/R-HSA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines TAS Homo sapiens 29033 R-HSA-1981128 https://reactome.org/PathwayBrowser/#/R-HSA-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 TAS Homo sapiens 29033 R-HSA-1981157 https://reactome.org/PathwayBrowser/#/R-HSA-1981157 Glucosylation of collagen propeptide hydroxylysines TAS Homo sapiens 29033 R-HSA-199803 https://reactome.org/PathwayBrowser/#/R-HSA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate TAS Homo sapiens 29033 R-HSA-204662 https://reactome.org/PathwayBrowser/#/R-HSA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A TAS Homo sapiens 29033 R-HSA-209823 https://reactome.org/PathwayBrowser/#/R-HSA-209823 Tyrosine is hydroxylated to dopa TAS Homo sapiens 29033 R-HSA-209828 https://reactome.org/PathwayBrowser/#/R-HSA-209828 Tryptophan is hydroxylated TAS Homo sapiens 29033 R-HSA-2161768 https://reactome.org/PathwayBrowser/#/R-HSA-2161768 EXA4 is converted to EXC4 by LTC4S TAS Homo sapiens 29033 R-HSA-2161775 https://reactome.org/PathwayBrowser/#/R-HSA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 TAS Homo sapiens 29033 R-HSA-2161794 https://reactome.org/PathwayBrowser/#/R-HSA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 TAS Homo sapiens 29033 R-HSA-2161907 https://reactome.org/PathwayBrowser/#/R-HSA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 TAS Homo sapiens 29033 R-HSA-2161917 https://reactome.org/PathwayBrowser/#/R-HSA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 TAS Homo sapiens 29033 R-HSA-2161948 https://reactome.org/PathwayBrowser/#/R-HSA-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 TAS Homo sapiens 29033 R-HSA-2161950 https://reactome.org/PathwayBrowser/#/R-HSA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B TAS Homo sapiens 29033 R-HSA-2161964 https://reactome.org/PathwayBrowser/#/R-HSA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 TAS Homo sapiens 29033 R-HSA-2162002 https://reactome.org/PathwayBrowser/#/R-HSA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B TAS Homo sapiens 29033 R-HSA-2162019 https://reactome.org/PathwayBrowser/#/R-HSA-2162019 LTA4 is converted to EXA4 by ALOX15 TAS Homo sapiens 29033 R-HSA-2162186 https://reactome.org/PathwayBrowser/#/R-HSA-2162186 COQ3 methylates DeMQ10H2 TAS Homo sapiens 29033 R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB IEA Homo sapiens 29033 R-HSA-2162188 https://reactome.org/PathwayBrowser/#/R-HSA-2162188 COQ5 methylates MDMQ10H2 TAS Homo sapiens 29033 R-HSA-2162193 https://reactome.org/PathwayBrowser/#/R-HSA-2162193 COQ3 methylates DHDB TAS Homo sapiens 29033 R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 29033 R-HSA-2172678 https://reactome.org/PathwayBrowser/#/R-HSA-2172678 PHF8 demethylates histone H4K20me1 TAS Homo sapiens 29033 R-HSA-2245218 https://reactome.org/PathwayBrowser/#/R-HSA-2245218 CDK1 phosphorylates PHF8 TAS Homo sapiens 29033 R-HSA-2301205 https://reactome.org/PathwayBrowser/#/R-HSA-2301205 SETD8 monomethylates histone H4 TAS Homo sapiens 29033 R-HSA-265296 https://reactome.org/PathwayBrowser/#/R-HSA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 TAS Homo sapiens 29033 R-HSA-266050 https://reactome.org/PathwayBrowser/#/R-HSA-266050 LTA4 is converted to LTC4 by LTC4S TAS Homo sapiens 29033 R-HSA-266051 https://reactome.org/PathwayBrowser/#/R-HSA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 TAS Homo sapiens 29033 R-HSA-3222593 https://reactome.org/PathwayBrowser/#/R-HSA-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter TAS Homo sapiens 29033 R-HSA-3223200 https://reactome.org/PathwayBrowser/#/R-HSA-3223200 Demethylation of H3K27Me3 by KDM6B stimulates p16INK4A transcription, while binding of PRC1.4 complex to H3K27Me3 represses p16INK4A transcription TAS Homo sapiens 29033 R-HSA-389639 https://reactome.org/PathwayBrowser/#/R-HSA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 TAS Homo sapiens 29033 R-HSA-428259 https://reactome.org/PathwayBrowser/#/R-HSA-428259 DEGS1 dehydrogenates dihydroceramide TAS Homo sapiens 29033 R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 29033 R-HSA-429016 https://reactome.org/PathwayBrowser/#/R-HSA-429016 ALOX5 is phosphorylated by MAPKAP2 TAS Homo sapiens 29033 R-HSA-435171 https://reactome.org/PathwayBrowser/#/R-HSA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages TAS Homo sapiens 29033 R-HSA-435349 https://reactome.org/PathwayBrowser/#/R-HSA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol TAS Homo sapiens 29033 R-HSA-442368 https://reactome.org/PathwayBrowser/#/R-HSA-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region TAS Homo sapiens 29033 R-HSA-5164399 https://reactome.org/PathwayBrowser/#/R-HSA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION TAS Homo sapiens 29033 R-HSA-5220952 https://reactome.org/PathwayBrowser/#/R-HSA-5220952 TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine IEA Homo sapiens 29033 R-HSA-5220990 https://reactome.org/PathwayBrowser/#/R-HSA-5220990 TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine IEA Homo sapiens 29033 R-HSA-5221014 https://reactome.org/PathwayBrowser/#/R-HSA-5221014 TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine IEA Homo sapiens 29033 R-HSA-5621402 https://reactome.org/PathwayBrowser/#/R-HSA-5621402 Defective CP does not oxidise Fe2+ to Fe3+ TAS Homo sapiens 29033 R-HSA-5623558 https://reactome.org/PathwayBrowser/#/R-HSA-5623558 Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol TAS Homo sapiens 29033 R-HSA-5649483 https://reactome.org/PathwayBrowser/#/R-HSA-5649483 Defective PAH does not hydroxylate L-Phe to L-Tyr TAS Homo sapiens 29033 R-HSA-5655733 https://reactome.org/PathwayBrowser/#/R-HSA-5655733 Defective SLC40A1 does not transport Fe2+ from cytosol to extracellular region TAS Homo sapiens 29033 R-HSA-5657617 https://reactome.org/PathwayBrowser/#/R-HSA-5657617 ALKBH3 associated with ASCC1:ASCC2:ASCC3 binds alkylated dsDNA containing 3-meC TAS Homo sapiens 29033 R-HSA-5657637 https://reactome.org/PathwayBrowser/#/R-HSA-5657637 ALKBH3 associated with ASCC1:ASCC2:ASCC3 binds alkylated dsDNA containing 1-meA TAS Homo sapiens 29033 R-HSA-5657641 https://reactome.org/PathwayBrowser/#/R-HSA-5657641 ALKBH2 binds alkylated DNA containing 1-meA TAS Homo sapiens 29033 R-HSA-5657642 https://reactome.org/PathwayBrowser/#/R-HSA-5657642 ALKBH3 in complex with ASCC1:ASCC2:ASCC3 binds alkylated DNA containing 1-etA TAS Homo sapiens 29033 R-HSA-5657649 https://reactome.org/PathwayBrowser/#/R-HSA-5657649 ALKBH2 binds alkylated DNA containing 1-etA TAS Homo sapiens 29033 R-HSA-5657665 https://reactome.org/PathwayBrowser/#/R-HSA-5657665 ALKBH2 binds alkylated dsDNA containing 3-meC TAS Homo sapiens 29033 R-HSA-5678327 https://reactome.org/PathwayBrowser/#/R-HSA-5678327 MIOX oxidises Ins to GlcA TAS Homo sapiens 29033 R-HSA-5690873 https://reactome.org/PathwayBrowser/#/R-HSA-5690873 ACO1 binds 4Fe-4S TAS Homo sapiens 29033 R-HSA-5690886 https://reactome.org/PathwayBrowser/#/R-HSA-5690886 ACO1, IREB2 bind IREs in TFRC, ALAD, FTL, FTH1 mRNAs TAS Homo sapiens 29033 R-HSA-5691107 https://reactome.org/PathwayBrowser/#/R-HSA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) TAS Homo sapiens 29033 R-HSA-5693761 https://reactome.org/PathwayBrowser/#/R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids TAS Homo sapiens 29033 R-HSA-6783455 https://reactome.org/PathwayBrowser/#/R-HSA-6783455 TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 29033 R-HSA-6786500 https://reactome.org/PathwayBrowser/#/R-HSA-6786500 ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 IEA Homo sapiens 29033 R-HSA-6789109 https://reactome.org/PathwayBrowser/#/R-HSA-6789109 Superoxide anion reacts with Fe-S cluster TAS Homo sapiens 29033 R-HSA-6789160 https://reactome.org/PathwayBrowser/#/R-HSA-6789160 Hydrogen peroxide and Fe2+ react to hydroxyl, hydroxide and Fe3+ TAS Homo sapiens 29033 R-HSA-6789208 https://reactome.org/PathwayBrowser/#/R-HSA-6789208 HOCl-induced glycosaminoglycan fragmentation TAS Homo sapiens 29033 R-HSA-6814153 https://reactome.org/PathwayBrowser/#/R-HSA-6814153 ADO oxidises 2AET to HTAU TAS Homo sapiens 29033 R-HSA-71118 https://reactome.org/PathwayBrowser/#/R-HSA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr TAS Homo sapiens 29033 R-HSA-71163 https://reactome.org/PathwayBrowser/#/R-HSA-71163 HPD dioxygenates HPP TAS Homo sapiens 29033 R-HSA-71164 https://reactome.org/PathwayBrowser/#/R-HSA-71164 HGD dioxygenates homogentisate TAS Homo sapiens 29033 R-HSA-71218 https://reactome.org/PathwayBrowser/#/R-HSA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde TAS Homo sapiens 29033 R-HSA-71241 https://reactome.org/PathwayBrowser/#/R-HSA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA TAS Homo sapiens 29033 R-HSA-71261 https://reactome.org/PathwayBrowser/#/R-HSA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA TAS Homo sapiens 29033 R-HSA-71303 https://reactome.org/PathwayBrowser/#/R-HSA-71303 RPE dimers isomerise RU5P to XY5P TAS Homo sapiens 29033 R-HSA-73815 https://reactome.org/PathwayBrowser/#/R-HSA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate TAS Homo sapiens 29033 R-HSA-76494 https://reactome.org/PathwayBrowser/#/R-HSA-76494 POR reduces CYP450:Fe3+ to CYP450:Fe2+ TAS Homo sapiens 29033 R-HSA-8857692 https://reactome.org/PathwayBrowser/#/R-HSA-8857692 RNA demethylases demethylate N6-methyladenosine RNA TAS Homo sapiens 29033 R-HSA-8948219 https://reactome.org/PathwayBrowser/#/R-HSA-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides TAS Homo sapiens 29033 R-HSA-8948222 https://reactome.org/PathwayBrowser/#/R-HSA-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates TAS Homo sapiens 29033 R-HSA-8948224 https://reactome.org/PathwayBrowser/#/R-HSA-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates TAS Homo sapiens 29033 R-HSA-8948226 https://reactome.org/PathwayBrowser/#/R-HSA-8948226 Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates TAS Homo sapiens 29033 R-HSA-8948230 https://reactome.org/PathwayBrowser/#/R-HSA-8948230 P3HB binds 4-Hyp-collagen propeptides TAS Homo sapiens 29033 R-HSA-8948232 https://reactome.org/PathwayBrowser/#/R-HSA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases TAS Homo sapiens 29033 R-HSA-8979071 https://reactome.org/PathwayBrowser/#/R-HSA-8979071 KDM6B binds iron TAS Homo sapiens 29033 R-HSA-9020274 https://reactome.org/PathwayBrowser/#/R-HSA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA TAS Homo sapiens 29033 R-HSA-9024983 https://reactome.org/PathwayBrowser/#/R-HSA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA TAS Homo sapiens 29033 R-HSA-9025957 https://reactome.org/PathwayBrowser/#/R-HSA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 TAS Homo sapiens 29033 R-HSA-9026006 https://reactome.org/PathwayBrowser/#/R-HSA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 TAS Homo sapiens 29033 R-HSA-9026007 https://reactome.org/PathwayBrowser/#/R-HSA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 TAS Homo sapiens 29033 R-HSA-904830 https://reactome.org/PathwayBrowser/#/R-HSA-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region TAS Homo sapiens 29033 R-HSA-917805 https://reactome.org/PathwayBrowser/#/R-HSA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ TAS Homo sapiens 29033 R-HSA-917811 https://reactome.org/PathwayBrowser/#/R-HSA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ TAS Homo sapiens 29033 R-HSA-917891 https://reactome.org/PathwayBrowser/#/R-HSA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ TAS Homo sapiens 29033 R-HSA-917933 https://reactome.org/PathwayBrowser/#/R-HSA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ TAS Homo sapiens 29033 R-HSA-917936 https://reactome.org/PathwayBrowser/#/R-HSA-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol TAS Homo sapiens 29033 R-HSA-9629578 https://reactome.org/PathwayBrowser/#/R-HSA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 TAS Homo sapiens 29033 R-HSA-9629591 https://reactome.org/PathwayBrowser/#/R-HSA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 TAS Homo sapiens 29033 R-HSA-9629869 https://reactome.org/PathwayBrowser/#/R-HSA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 TAS Homo sapiens 29033 R-HSA-9629888 https://reactome.org/PathwayBrowser/#/R-HSA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 TAS Homo sapiens 29033 R-HSA-9629946 https://reactome.org/PathwayBrowser/#/R-HSA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 TAS Homo sapiens 29033 R-HSA-9630022 https://reactome.org/PathwayBrowser/#/R-HSA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 TAS Homo sapiens 29033 R-HSA-9630769 https://reactome.org/PathwayBrowser/#/R-HSA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 TAS Homo sapiens 29033 R-HSA-9630967 https://reactome.org/PathwayBrowser/#/R-HSA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A TAS Homo sapiens 29033 R-HSA-9630993 https://reactome.org/PathwayBrowser/#/R-HSA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 TAS Homo sapiens 29033 R-HSA-9631355 https://reactome.org/PathwayBrowser/#/R-HSA-9631355 ASPH:Fe2+ hydroxylates an aspartate residue of F9 IEA Homo sapiens 29033 R-HSA-9707186 https://reactome.org/PathwayBrowser/#/R-HSA-9707186 ALOX5 binds ALOX5 inhibitors TAS Homo sapiens 29033 R-HSA-975635 https://reactome.org/PathwayBrowser/#/R-HSA-975635 BCMO1:Fe2+ cleaves betaC to atRAL TAS Homo sapiens 29033 R-HSA-9817458 https://reactome.org/PathwayBrowser/#/R-HSA-9817458 TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 IEA Homo sapiens 29033 R-HSA-9822461 https://reactome.org/PathwayBrowser/#/R-HSA-9822461 KDM5B demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 29033 R-HSA-9822467 https://reactome.org/PathwayBrowser/#/R-HSA-9822467 KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 29033 R-HSA-9822591 https://reactome.org/PathwayBrowser/#/R-HSA-9822591 TET3 binds chromatin with H3K17me2a and 5-mC:METTL23:STGP4 IEA Homo sapiens 29033 R-HSA-9822914 https://reactome.org/PathwayBrowser/#/R-HSA-9822914 KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 29033 R-HSA-9822985 https://reactome.org/PathwayBrowser/#/R-HSA-9822985 KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 29033 R-HSA-9854368 https://reactome.org/PathwayBrowser/#/R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S TAS Homo sapiens 29033 R-HSA-9854405 https://reactome.org/PathwayBrowser/#/R-HSA-9854405 Frataxin transfers Fe2+ to ACO2 TAS Homo sapiens 29033 R-HSA-9854984 https://reactome.org/PathwayBrowser/#/R-HSA-9854984 Transfer of Fe-S clusters to SDHB TAS Homo sapiens 29033 R-MMU-111285 https://reactome.org/PathwayBrowser/#/R-MMU-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Mus musculus 29033 R-MMU-111289 https://reactome.org/PathwayBrowser/#/R-MMU-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Mus musculus 29033 R-MMU-1234159 https://reactome.org/PathwayBrowser/#/R-MMU-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Mus musculus 29033 R-MMU-1234163 https://reactome.org/PathwayBrowser/#/R-MMU-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Mus musculus 29033 R-MMU-1234164 https://reactome.org/PathwayBrowser/#/R-MMU-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Mus musculus 29033 R-MMU-1234165 https://reactome.org/PathwayBrowser/#/R-MMU-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Mus musculus 29033 R-MMU-1234173 https://reactome.org/PathwayBrowser/#/R-MMU-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Mus musculus 29033 R-MMU-1234177 https://reactome.org/PathwayBrowser/#/R-MMU-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Mus musculus 29033 R-MMU-1234181 https://reactome.org/PathwayBrowser/#/R-MMU-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Mus musculus 29033 R-MMU-1234183 https://reactome.org/PathwayBrowser/#/R-MMU-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Mus musculus 29033 R-MMU-1237119 https://reactome.org/PathwayBrowser/#/R-MMU-1237119 Acireductone is oxidized to MOB IEA Mus musculus 29033 R-MMU-1362408 https://reactome.org/PathwayBrowser/#/R-MMU-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Mus musculus 29033 R-MMU-1362412 https://reactome.org/PathwayBrowser/#/R-MMU-1362412 Mitoferrin Transports Iron Across the Mitochondrial Inner Membrane TAS Mus musculus 29033 R-MMU-1362416 https://reactome.org/PathwayBrowser/#/R-MMU-1362416 Frataxin binds iron IEA Mus musculus 29033 R-MMU-1562626 https://reactome.org/PathwayBrowser/#/R-MMU-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Mus musculus 29033 R-MMU-1614645 https://reactome.org/PathwayBrowser/#/R-MMU-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Mus musculus 29033 R-MMU-1650808 https://reactome.org/PathwayBrowser/#/R-MMU-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Mus musculus 29033 R-MMU-180038 https://reactome.org/PathwayBrowser/#/R-MMU-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function IEA Mus musculus 29033 R-MMU-189398 https://reactome.org/PathwayBrowser/#/R-MMU-189398 HMOX1 dimer, HMOX2 cleave heme IEA Mus musculus 29033 R-MMU-189465 https://reactome.org/PathwayBrowser/#/R-MMU-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Mus musculus 29033 R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 29033 R-MMU-1980233 https://reactome.org/PathwayBrowser/#/R-MMU-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Mus musculus 29033 R-MMU-1981104 https://reactome.org/PathwayBrowser/#/R-MMU-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Mus musculus 29033 R-MMU-1981128 https://reactome.org/PathwayBrowser/#/R-MMU-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Mus musculus 29033 R-MMU-1981157 https://reactome.org/PathwayBrowser/#/R-MMU-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Mus musculus 29033 R-MMU-199803 https://reactome.org/PathwayBrowser/#/R-MMU-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Mus musculus 29033 R-MMU-204662 https://reactome.org/PathwayBrowser/#/R-MMU-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Mus musculus 29033 R-MMU-209823 https://reactome.org/PathwayBrowser/#/R-MMU-209823 Tyrosine is hydroxylated to dopa IEA Mus musculus 29033 R-MMU-209828 https://reactome.org/PathwayBrowser/#/R-MMU-209828 Tryptophan is hydroxylated IEA Mus musculus 29033 R-MMU-2161768 https://reactome.org/PathwayBrowser/#/R-MMU-2161768 EXA4 is converted to EXC4 by LTC4S IEA Mus musculus 29033 R-MMU-2161775 https://reactome.org/PathwayBrowser/#/R-MMU-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Mus musculus 29033 R-MMU-2161794 https://reactome.org/PathwayBrowser/#/R-MMU-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Mus musculus 29033 R-MMU-2161907 https://reactome.org/PathwayBrowser/#/R-MMU-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Mus musculus 29033 R-MMU-2161917 https://reactome.org/PathwayBrowser/#/R-MMU-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Mus musculus 29033 R-MMU-2161948 https://reactome.org/PathwayBrowser/#/R-MMU-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Mus musculus 29033 R-MMU-2161950 https://reactome.org/PathwayBrowser/#/R-MMU-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Mus musculus 29033 R-MMU-2161964 https://reactome.org/PathwayBrowser/#/R-MMU-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Mus musculus 29033 R-MMU-2162002 https://reactome.org/PathwayBrowser/#/R-MMU-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Mus musculus 29033 R-MMU-2162019 https://reactome.org/PathwayBrowser/#/R-MMU-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Mus musculus 29033 R-MMU-2162186 https://reactome.org/PathwayBrowser/#/R-MMU-2162186 COQ3 methylates DeMQ10H2 IEA Mus musculus 29033 R-MMU-2162188 https://reactome.org/PathwayBrowser/#/R-MMU-2162188 COQ5 methylates MDMQ10H2 IEA Mus musculus 29033 R-MMU-2162193 https://reactome.org/PathwayBrowser/#/R-MMU-2162193 COQ3 methylates DHDB IEA Mus musculus 29033 R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 29033 R-MMU-265296 https://reactome.org/PathwayBrowser/#/R-MMU-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Mus musculus 29033 R-MMU-266050 https://reactome.org/PathwayBrowser/#/R-MMU-266050 LTA4 is converted to LTC4 by LTC4S IEA Mus musculus 29033 R-MMU-266051 https://reactome.org/PathwayBrowser/#/R-MMU-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Mus musculus 29033 R-MMU-389639 https://reactome.org/PathwayBrowser/#/R-MMU-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Mus musculus 29033 R-MMU-428259 https://reactome.org/PathwayBrowser/#/R-MMU-428259 DEGS1 dehydrogenates dihydroceramide IEA Mus musculus 29033 R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 29033 R-MMU-429016 https://reactome.org/PathwayBrowser/#/R-MMU-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Mus musculus 29033 R-MMU-435171 https://reactome.org/PathwayBrowser/#/R-MMU-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Mus musculus 29033 R-MMU-435349 https://reactome.org/PathwayBrowser/#/R-MMU-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Mus musculus 29033 R-MMU-442368 https://reactome.org/PathwayBrowser/#/R-MMU-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Mus musculus 29033 R-MMU-5164399 https://reactome.org/PathwayBrowser/#/R-MMU-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Mus musculus 29033 R-MMU-5220931 https://reactome.org/PathwayBrowser/#/R-MMU-5220931 Tet1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine TAS Mus musculus 29033 R-MMU-5220936 https://reactome.org/PathwayBrowser/#/R-MMU-5220936 Tet1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine TAS Mus musculus 29033 R-MMU-5220944 https://reactome.org/PathwayBrowser/#/R-MMU-5220944 Tet1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine TAS Mus musculus 29033 R-MMU-5678327 https://reactome.org/PathwayBrowser/#/R-MMU-5678327 MIOX oxidises Ins to GlcA IEA Mus musculus 29033 R-MMU-5690873 https://reactome.org/PathwayBrowser/#/R-MMU-5690873 ACO1 binds 4Fe-4S IEA Mus musculus 29033 R-MMU-5691107 https://reactome.org/PathwayBrowser/#/R-MMU-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Mus musculus 29033 R-MMU-5693761 https://reactome.org/PathwayBrowser/#/R-MMU-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Mus musculus 29033 R-MMU-6814153 https://reactome.org/PathwayBrowser/#/R-MMU-6814153 ADO oxidises 2AET to HTAU IEA Mus musculus 29033 R-MMU-71118 https://reactome.org/PathwayBrowser/#/R-MMU-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Mus musculus 29033 R-MMU-71163 https://reactome.org/PathwayBrowser/#/R-MMU-71163 HPD dioxygenates HPP IEA Mus musculus 29033 R-MMU-71164 https://reactome.org/PathwayBrowser/#/R-MMU-71164 HGD dioxygenates homogentisate IEA Mus musculus 29033 R-MMU-71218 https://reactome.org/PathwayBrowser/#/R-MMU-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Mus musculus 29033 R-MMU-71241 https://reactome.org/PathwayBrowser/#/R-MMU-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Mus musculus 29033 R-MMU-71261 https://reactome.org/PathwayBrowser/#/R-MMU-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Mus musculus 29033 R-MMU-71303 https://reactome.org/PathwayBrowser/#/R-MMU-71303 RPE dimers isomerise RU5P to XY5P IEA Mus musculus 29033 R-MMU-73815 https://reactome.org/PathwayBrowser/#/R-MMU-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Mus musculus 29033 R-MMU-8857692 https://reactome.org/PathwayBrowser/#/R-MMU-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Mus musculus 29033 R-MMU-8948219 https://reactome.org/PathwayBrowser/#/R-MMU-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Mus musculus 29033 R-MMU-8948222 https://reactome.org/PathwayBrowser/#/R-MMU-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Mus musculus 29033 R-MMU-8948224 https://reactome.org/PathwayBrowser/#/R-MMU-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Mus musculus 29033 R-MMU-8948232 https://reactome.org/PathwayBrowser/#/R-MMU-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Mus musculus 29033 R-MMU-8979071 https://reactome.org/PathwayBrowser/#/R-MMU-8979071 KDM6B binds iron IEA Mus musculus 29033 R-MMU-9020274 https://reactome.org/PathwayBrowser/#/R-MMU-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Mus musculus 29033 R-MMU-9024983 https://reactome.org/PathwayBrowser/#/R-MMU-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Mus musculus 29033 R-MMU-9025957 https://reactome.org/PathwayBrowser/#/R-MMU-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Mus musculus 29033 R-MMU-9026006 https://reactome.org/PathwayBrowser/#/R-MMU-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Mus musculus 29033 R-MMU-9026007 https://reactome.org/PathwayBrowser/#/R-MMU-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Mus musculus 29033 R-MMU-904830 https://reactome.org/PathwayBrowser/#/R-MMU-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Mus musculus 29033 R-MMU-917805 https://reactome.org/PathwayBrowser/#/R-MMU-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Mus musculus 29033 R-MMU-917811 https://reactome.org/PathwayBrowser/#/R-MMU-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Mus musculus 29033 R-MMU-917891 https://reactome.org/PathwayBrowser/#/R-MMU-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Mus musculus 29033 R-MMU-917933 https://reactome.org/PathwayBrowser/#/R-MMU-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Mus musculus 29033 R-MMU-917936 https://reactome.org/PathwayBrowser/#/R-MMU-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Mus musculus 29033 R-MMU-9629578 https://reactome.org/PathwayBrowser/#/R-MMU-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Mus musculus 29033 R-MMU-9629591 https://reactome.org/PathwayBrowser/#/R-MMU-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Mus musculus 29033 R-MMU-9629869 https://reactome.org/PathwayBrowser/#/R-MMU-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Mus musculus 29033 R-MMU-9629888 https://reactome.org/PathwayBrowser/#/R-MMU-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Mus musculus 29033 R-MMU-9629946 https://reactome.org/PathwayBrowser/#/R-MMU-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Mus musculus 29033 R-MMU-9630022 https://reactome.org/PathwayBrowser/#/R-MMU-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Mus musculus 29033 R-MMU-9630769 https://reactome.org/PathwayBrowser/#/R-MMU-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Mus musculus 29033 R-MMU-9630967 https://reactome.org/PathwayBrowser/#/R-MMU-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Mus musculus 29033 R-MMU-9630993 https://reactome.org/PathwayBrowser/#/R-MMU-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Mus musculus 29033 R-MMU-9707186 https://reactome.org/PathwayBrowser/#/R-MMU-9707186 ALOX5 binds ALOX5 inhibitors IEA Mus musculus 29033 R-MMU-975635 https://reactome.org/PathwayBrowser/#/R-MMU-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Mus musculus 29033 R-MMU-9817463 https://reactome.org/PathwayBrowser/#/R-MMU-9817463 Tet3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 dimethylated on lysine-9 TAS Mus musculus 29033 R-MMU-9822448 https://reactome.org/PathwayBrowser/#/R-MMU-9822448 Kdm5b demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 29033 R-MMU-9822463 https://reactome.org/PathwayBrowser/#/R-MMU-9822463 Kdm5a demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 29033 R-MMU-9822631 https://reactome.org/PathwayBrowser/#/R-MMU-9822631 Tet3 binds chromatin with H3K17me2a and 5-mC:Mettl23:Stgp4 TAS Mus musculus 29033 R-MMU-9822924 https://reactome.org/PathwayBrowser/#/R-MMU-9822924 Kdm6b (Jmjd3) demethylates histone H3 trimethyllysine-27 (H3K27me3) TAS Mus musculus 29033 R-MMU-9822964 https://reactome.org/PathwayBrowser/#/R-MMU-9822964 Kdm6a (Utx) demethylates trimethylated histone H3 lysine-27 (H3K27me3) TAS Mus musculus 29033 R-MMU-9854368 https://reactome.org/PathwayBrowser/#/R-MMU-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Mus musculus 29033 R-MMU-9854405 https://reactome.org/PathwayBrowser/#/R-MMU-9854405 Frataxin transfers Fe2+ to ACO2 IEA Mus musculus 29033 R-MMU-9854984 https://reactome.org/PathwayBrowser/#/R-MMU-9854984 Transfer of Fe-S clusters to SDHB IEA Mus musculus 29033 R-PFA-1362408 https://reactome.org/PathwayBrowser/#/R-PFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Plasmodium falciparum 29033 R-PFA-1362416 https://reactome.org/PathwayBrowser/#/R-PFA-1362416 Frataxin binds iron IEA Plasmodium falciparum 29033 R-PFA-189465 https://reactome.org/PathwayBrowser/#/R-PFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Plasmodium falciparum 29033 R-PFA-199803 https://reactome.org/PathwayBrowser/#/R-PFA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Plasmodium falciparum 29033 R-PFA-204662 https://reactome.org/PathwayBrowser/#/R-PFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Plasmodium falciparum 29033 R-PFA-2172678 https://reactome.org/PathwayBrowser/#/R-PFA-2172678 PHF8 demethylates histone H4K20me1 IEA Plasmodium falciparum 29033 R-PFA-2301205 https://reactome.org/PathwayBrowser/#/R-PFA-2301205 SETD8 monomethylates histone H4 IEA Plasmodium falciparum 29033 R-PFA-435171 https://reactome.org/PathwayBrowser/#/R-PFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Plasmodium falciparum 29033 R-PFA-435349 https://reactome.org/PathwayBrowser/#/R-PFA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Plasmodium falciparum 29033 R-PFA-5690873 https://reactome.org/PathwayBrowser/#/R-PFA-5690873 ACO1 binds 4Fe-4S IEA Plasmodium falciparum 29033 R-PFA-71303 https://reactome.org/PathwayBrowser/#/R-PFA-71303 RPE dimers isomerise RU5P to XY5P IEA Plasmodium falciparum 29033 R-RNO-111285 https://reactome.org/PathwayBrowser/#/R-RNO-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Rattus norvegicus 29033 R-RNO-111289 https://reactome.org/PathwayBrowser/#/R-RNO-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Rattus norvegicus 29033 R-RNO-1234159 https://reactome.org/PathwayBrowser/#/R-RNO-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Rattus norvegicus 29033 R-RNO-1234163 https://reactome.org/PathwayBrowser/#/R-RNO-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Rattus norvegicus 29033 R-RNO-1234164 https://reactome.org/PathwayBrowser/#/R-RNO-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Rattus norvegicus 29033 R-RNO-1234165 https://reactome.org/PathwayBrowser/#/R-RNO-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 29033 R-RNO-1234173 https://reactome.org/PathwayBrowser/#/R-RNO-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 29033 R-RNO-1234177 https://reactome.org/PathwayBrowser/#/R-RNO-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 29033 R-RNO-1234181 https://reactome.org/PathwayBrowser/#/R-RNO-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 29033 R-RNO-1234183 https://reactome.org/PathwayBrowser/#/R-RNO-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Rattus norvegicus 29033 R-RNO-1237119 https://reactome.org/PathwayBrowser/#/R-RNO-1237119 Acireductone is oxidized to MOB IEA Rattus norvegicus 29033 R-RNO-1362408 https://reactome.org/PathwayBrowser/#/R-RNO-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Rattus norvegicus 29033 R-RNO-1362416 https://reactome.org/PathwayBrowser/#/R-RNO-1362416 Frataxin binds iron IEA Rattus norvegicus 29033 R-RNO-1562626 https://reactome.org/PathwayBrowser/#/R-RNO-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Rattus norvegicus 29033 R-RNO-1614645 https://reactome.org/PathwayBrowser/#/R-RNO-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Rattus norvegicus 29033 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus 29033 R-RNO-180038 https://reactome.org/PathwayBrowser/#/R-RNO-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function IEA Rattus norvegicus 29033 R-RNO-189398 https://reactome.org/PathwayBrowser/#/R-RNO-189398 HMOX1 dimer, HMOX2 cleave heme IEA Rattus norvegicus 29033 R-RNO-189465 https://reactome.org/PathwayBrowser/#/R-RNO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Rattus norvegicus 29033 R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 29033 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus 29033 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus 29033 R-RNO-1981128 https://reactome.org/PathwayBrowser/#/R-RNO-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Rattus norvegicus 29033 R-RNO-1981157 https://reactome.org/PathwayBrowser/#/R-RNO-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Rattus norvegicus 29033 R-RNO-199803 https://reactome.org/PathwayBrowser/#/R-RNO-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Rattus norvegicus 29033 R-RNO-204662 https://reactome.org/PathwayBrowser/#/R-RNO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Rattus norvegicus 29033 R-RNO-209823 https://reactome.org/PathwayBrowser/#/R-RNO-209823 Tyrosine is hydroxylated to dopa IEA Rattus norvegicus 29033 R-RNO-209828 https://reactome.org/PathwayBrowser/#/R-RNO-209828 Tryptophan is hydroxylated IEA Rattus norvegicus 29033 R-RNO-2161768 https://reactome.org/PathwayBrowser/#/R-RNO-2161768 EXA4 is converted to EXC4 by LTC4S IEA Rattus norvegicus 29033 R-RNO-2161775 https://reactome.org/PathwayBrowser/#/R-RNO-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Rattus norvegicus 29033 R-RNO-2161794 https://reactome.org/PathwayBrowser/#/R-RNO-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Rattus norvegicus 29033 R-RNO-2161907 https://reactome.org/PathwayBrowser/#/R-RNO-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Rattus norvegicus 29033 R-RNO-2161917 https://reactome.org/PathwayBrowser/#/R-RNO-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Rattus norvegicus 29033 R-RNO-2161948 https://reactome.org/PathwayBrowser/#/R-RNO-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Rattus norvegicus 29033 R-RNO-2161950 https://reactome.org/PathwayBrowser/#/R-RNO-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Rattus norvegicus 29033 R-RNO-2161964 https://reactome.org/PathwayBrowser/#/R-RNO-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Rattus norvegicus 29033 R-RNO-2162002 https://reactome.org/PathwayBrowser/#/R-RNO-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Rattus norvegicus 29033 R-RNO-2162019 https://reactome.org/PathwayBrowser/#/R-RNO-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Rattus norvegicus 29033 R-RNO-2162186 https://reactome.org/PathwayBrowser/#/R-RNO-2162186 COQ3 methylates DeMQ10H2 IEA Rattus norvegicus 29033 R-RNO-2162188 https://reactome.org/PathwayBrowser/#/R-RNO-2162188 COQ5 methylates MDMQ10H2 IEA Rattus norvegicus 29033 R-RNO-2162193 https://reactome.org/PathwayBrowser/#/R-RNO-2162193 COQ3 methylates DHDB IEA Rattus norvegicus 29033 R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 29033 R-RNO-2172678 https://reactome.org/PathwayBrowser/#/R-RNO-2172678 PHF8 demethylates histone H4K20me1 IEA Rattus norvegicus 29033 R-RNO-2301205 https://reactome.org/PathwayBrowser/#/R-RNO-2301205 SETD8 monomethylates histone H4 IEA Rattus norvegicus 29033 R-RNO-265296 https://reactome.org/PathwayBrowser/#/R-RNO-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Rattus norvegicus 29033 R-RNO-266050 https://reactome.org/PathwayBrowser/#/R-RNO-266050 LTA4 is converted to LTC4 by LTC4S IEA Rattus norvegicus 29033 R-RNO-266051 https://reactome.org/PathwayBrowser/#/R-RNO-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Rattus norvegicus 29033 R-RNO-3222593 https://reactome.org/PathwayBrowser/#/R-RNO-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Rattus norvegicus 29033 R-RNO-389639 https://reactome.org/PathwayBrowser/#/R-RNO-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Rattus norvegicus 29033 R-RNO-428259 https://reactome.org/PathwayBrowser/#/R-RNO-428259 DEGS1 dehydrogenates dihydroceramide IEA Rattus norvegicus 29033 R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 29033 R-RNO-429016 https://reactome.org/PathwayBrowser/#/R-RNO-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Rattus norvegicus 29033 R-RNO-435171 https://reactome.org/PathwayBrowser/#/R-RNO-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Rattus norvegicus 29033 R-RNO-435349 https://reactome.org/PathwayBrowser/#/R-RNO-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Rattus norvegicus 29033 R-RNO-442368 https://reactome.org/PathwayBrowser/#/R-RNO-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Rattus norvegicus 29033 R-RNO-5164399 https://reactome.org/PathwayBrowser/#/R-RNO-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Rattus norvegicus 29033 R-RNO-5678327 https://reactome.org/PathwayBrowser/#/R-RNO-5678327 MIOX oxidises Ins to GlcA IEA Rattus norvegicus 29033 R-RNO-5690873 https://reactome.org/PathwayBrowser/#/R-RNO-5690873 ACO1 binds 4Fe-4S IEA Rattus norvegicus 29033 R-RNO-5691107 https://reactome.org/PathwayBrowser/#/R-RNO-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Rattus norvegicus 29033 R-RNO-5693761 https://reactome.org/PathwayBrowser/#/R-RNO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Rattus norvegicus 29033 R-RNO-6814153 https://reactome.org/PathwayBrowser/#/R-RNO-6814153 ADO oxidises 2AET to HTAU IEA Rattus norvegicus 29033 R-RNO-71118 https://reactome.org/PathwayBrowser/#/R-RNO-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Rattus norvegicus 29033 R-RNO-71163 https://reactome.org/PathwayBrowser/#/R-RNO-71163 HPD dioxygenates HPP IEA Rattus norvegicus 29033 R-RNO-71164 https://reactome.org/PathwayBrowser/#/R-RNO-71164 HGD dioxygenates homogentisate IEA Rattus norvegicus 29033 R-RNO-71218 https://reactome.org/PathwayBrowser/#/R-RNO-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Rattus norvegicus 29033 R-RNO-71241 https://reactome.org/PathwayBrowser/#/R-RNO-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Rattus norvegicus 29033 R-RNO-71261 https://reactome.org/PathwayBrowser/#/R-RNO-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Rattus norvegicus 29033 R-RNO-71303 https://reactome.org/PathwayBrowser/#/R-RNO-71303 RPE dimers isomerise RU5P to XY5P IEA Rattus norvegicus 29033 R-RNO-73815 https://reactome.org/PathwayBrowser/#/R-RNO-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Rattus norvegicus 29033 R-RNO-8857692 https://reactome.org/PathwayBrowser/#/R-RNO-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Rattus norvegicus 29033 R-RNO-8948219 https://reactome.org/PathwayBrowser/#/R-RNO-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus 29033 R-RNO-8948222 https://reactome.org/PathwayBrowser/#/R-RNO-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus 29033 R-RNO-8948224 https://reactome.org/PathwayBrowser/#/R-RNO-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus 29033 R-RNO-8948232 https://reactome.org/PathwayBrowser/#/R-RNO-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Rattus norvegicus 29033 R-RNO-8979071 https://reactome.org/PathwayBrowser/#/R-RNO-8979071 KDM6B binds iron IEA Rattus norvegicus 29033 R-RNO-9020274 https://reactome.org/PathwayBrowser/#/R-RNO-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Rattus norvegicus 29033 R-RNO-9024983 https://reactome.org/PathwayBrowser/#/R-RNO-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Rattus norvegicus 29033 R-RNO-9025957 https://reactome.org/PathwayBrowser/#/R-RNO-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Rattus norvegicus 29033 R-RNO-9026006 https://reactome.org/PathwayBrowser/#/R-RNO-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Rattus norvegicus 29033 R-RNO-9026007 https://reactome.org/PathwayBrowser/#/R-RNO-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Rattus norvegicus 29033 R-RNO-904830 https://reactome.org/PathwayBrowser/#/R-RNO-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Rattus norvegicus 29033 R-RNO-917805 https://reactome.org/PathwayBrowser/#/R-RNO-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Rattus norvegicus 29033 R-RNO-917811 https://reactome.org/PathwayBrowser/#/R-RNO-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Rattus norvegicus 29033 R-RNO-917891 https://reactome.org/PathwayBrowser/#/R-RNO-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Rattus norvegicus 29033 R-RNO-917933 https://reactome.org/PathwayBrowser/#/R-RNO-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Rattus norvegicus 29033 R-RNO-917936 https://reactome.org/PathwayBrowser/#/R-RNO-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Rattus norvegicus 29033 R-RNO-9629578 https://reactome.org/PathwayBrowser/#/R-RNO-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Rattus norvegicus 29033 R-RNO-9629591 https://reactome.org/PathwayBrowser/#/R-RNO-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Rattus norvegicus 29033 R-RNO-9629869 https://reactome.org/PathwayBrowser/#/R-RNO-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Rattus norvegicus 29033 R-RNO-9629888 https://reactome.org/PathwayBrowser/#/R-RNO-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Rattus norvegicus 29033 R-RNO-9629946 https://reactome.org/PathwayBrowser/#/R-RNO-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Rattus norvegicus 29033 R-RNO-9630022 https://reactome.org/PathwayBrowser/#/R-RNO-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Rattus norvegicus 29033 R-RNO-9630769 https://reactome.org/PathwayBrowser/#/R-RNO-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Rattus norvegicus 29033 R-RNO-9630967 https://reactome.org/PathwayBrowser/#/R-RNO-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Rattus norvegicus 29033 R-RNO-9630993 https://reactome.org/PathwayBrowser/#/R-RNO-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Rattus norvegicus 29033 R-RNO-9707186 https://reactome.org/PathwayBrowser/#/R-RNO-9707186 ALOX5 binds ALOX5 inhibitors IEA Rattus norvegicus 29033 R-RNO-975635 https://reactome.org/PathwayBrowser/#/R-RNO-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Rattus norvegicus 29033 R-RNO-9854368 https://reactome.org/PathwayBrowser/#/R-RNO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Rattus norvegicus 29033 R-RNO-9854405 https://reactome.org/PathwayBrowser/#/R-RNO-9854405 Frataxin transfers Fe2+ to ACO2 IEA Rattus norvegicus 29033 R-SCE-1237119 https://reactome.org/PathwayBrowser/#/R-SCE-1237119 Acireductone is oxidized to MOB IEA Saccharomyces cerevisiae 29033 R-SCE-1362408 https://reactome.org/PathwayBrowser/#/R-SCE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Saccharomyces cerevisiae 29033 R-SCE-1362416 https://reactome.org/PathwayBrowser/#/R-SCE-1362416 Frataxin binds iron IEA Saccharomyces cerevisiae 29033 R-SCE-189465 https://reactome.org/PathwayBrowser/#/R-SCE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Saccharomyces cerevisiae 29033 R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 29033 R-SCE-199803 https://reactome.org/PathwayBrowser/#/R-SCE-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Saccharomyces cerevisiae 29033 R-SCE-204662 https://reactome.org/PathwayBrowser/#/R-SCE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Saccharomyces cerevisiae 29033 R-SCE-2162186 https://reactome.org/PathwayBrowser/#/R-SCE-2162186 COQ3 methylates DeMQ10H2 IEA Saccharomyces cerevisiae 29033 R-SCE-2162188 https://reactome.org/PathwayBrowser/#/R-SCE-2162188 COQ5 methylates MDMQ10H2 IEA Saccharomyces cerevisiae 29033 R-SCE-2162193 https://reactome.org/PathwayBrowser/#/R-SCE-2162193 COQ3 methylates DHDB IEA Saccharomyces cerevisiae 29033 R-SCE-2162194 https://reactome.org/PathwayBrowser/#/R-SCE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Saccharomyces cerevisiae 29033 R-SCE-2172678 https://reactome.org/PathwayBrowser/#/R-SCE-2172678 PHF8 demethylates histone H4K20me1 IEA Saccharomyces cerevisiae 29033 R-SCE-2466303 https://reactome.org/PathwayBrowser/#/R-SCE-2466303 MRS3,4 Transports Iron Across the Mitochondrial Inner Membrane TAS Saccharomyces cerevisiae 29033 R-SCE-3222593 https://reactome.org/PathwayBrowser/#/R-SCE-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Saccharomyces cerevisiae 29033 R-SCE-389639 https://reactome.org/PathwayBrowser/#/R-SCE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Saccharomyces cerevisiae 29033 R-SCE-5693761 https://reactome.org/PathwayBrowser/#/R-SCE-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Saccharomyces cerevisiae 29033 R-SCE-71218 https://reactome.org/PathwayBrowser/#/R-SCE-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Saccharomyces cerevisiae 29033 R-SCE-71261 https://reactome.org/PathwayBrowser/#/R-SCE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Saccharomyces cerevisiae 29033 R-SCE-71303 https://reactome.org/PathwayBrowser/#/R-SCE-71303 RPE dimers isomerise RU5P to XY5P IEA Saccharomyces cerevisiae 29033 R-SCE-8979071 https://reactome.org/PathwayBrowser/#/R-SCE-8979071 KDM6B binds iron IEA Saccharomyces cerevisiae 29033 R-SCE-9630769 https://reactome.org/PathwayBrowser/#/R-SCE-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Saccharomyces cerevisiae 29033 R-SCE-9854368 https://reactome.org/PathwayBrowser/#/R-SCE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Saccharomyces cerevisiae 29033 R-SCE-9854405 https://reactome.org/PathwayBrowser/#/R-SCE-9854405 Frataxin transfers Fe2+ to ACO2 IEA Saccharomyces cerevisiae 29033 R-SPO-1237119 https://reactome.org/PathwayBrowser/#/R-SPO-1237119 Acireductone is oxidized to MOB IEA Schizosaccharomyces pombe 29033 R-SPO-1362416 https://reactome.org/PathwayBrowser/#/R-SPO-1362416 Frataxin binds iron IEA Schizosaccharomyces pombe 29033 R-SPO-189465 https://reactome.org/PathwayBrowser/#/R-SPO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Schizosaccharomyces pombe 29033 R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 29033 R-SPO-199803 https://reactome.org/PathwayBrowser/#/R-SPO-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Schizosaccharomyces pombe 29033 R-SPO-204662 https://reactome.org/PathwayBrowser/#/R-SPO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Schizosaccharomyces pombe 29033 R-SPO-2162186 https://reactome.org/PathwayBrowser/#/R-SPO-2162186 COQ3 methylates DeMQ10H2 IEA Schizosaccharomyces pombe 29033 R-SPO-2162188 https://reactome.org/PathwayBrowser/#/R-SPO-2162188 COQ5 methylates MDMQ10H2 IEA Schizosaccharomyces pombe 29033 R-SPO-2162193 https://reactome.org/PathwayBrowser/#/R-SPO-2162193 COQ3 methylates DHDB IEA Schizosaccharomyces pombe 29033 R-SPO-2162194 https://reactome.org/PathwayBrowser/#/R-SPO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Schizosaccharomyces pombe 29033 R-SPO-2172678 https://reactome.org/PathwayBrowser/#/R-SPO-2172678 PHF8 demethylates histone H4K20me1 IEA Schizosaccharomyces pombe 29033 R-SPO-3222593 https://reactome.org/PathwayBrowser/#/R-SPO-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Schizosaccharomyces pombe 29033 R-SPO-428259 https://reactome.org/PathwayBrowser/#/R-SPO-428259 DEGS1 dehydrogenates dihydroceramide IEA Schizosaccharomyces pombe 29033 R-SPO-428260 https://reactome.org/PathwayBrowser/#/R-SPO-428260 DEGS2 oxygenates dihydroceramide IEA Schizosaccharomyces pombe 29033 R-SPO-5693761 https://reactome.org/PathwayBrowser/#/R-SPO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Schizosaccharomyces pombe 29033 R-SPO-71303 https://reactome.org/PathwayBrowser/#/R-SPO-71303 RPE dimers isomerise RU5P to XY5P IEA Schizosaccharomyces pombe 29033 R-SPO-8979071 https://reactome.org/PathwayBrowser/#/R-SPO-8979071 KDM6B binds iron IEA Schizosaccharomyces pombe 29033 R-SPO-9629946 https://reactome.org/PathwayBrowser/#/R-SPO-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Schizosaccharomyces pombe 29033 R-SPO-9630769 https://reactome.org/PathwayBrowser/#/R-SPO-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Schizosaccharomyces pombe 29033 R-SPO-9854368 https://reactome.org/PathwayBrowser/#/R-SPO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Schizosaccharomyces pombe 29033 R-SPO-9854405 https://reactome.org/PathwayBrowser/#/R-SPO-9854405 Frataxin transfers Fe2+ to ACO2 IEA Schizosaccharomyces pombe 29033 R-SSC-111285 https://reactome.org/PathwayBrowser/#/R-SSC-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Sus scrofa 29033 R-SSC-111289 https://reactome.org/PathwayBrowser/#/R-SSC-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Sus scrofa 29033 R-SSC-1234159 https://reactome.org/PathwayBrowser/#/R-SSC-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Sus scrofa 29033 R-SSC-1234163 https://reactome.org/PathwayBrowser/#/R-SSC-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Sus scrofa 29033 R-SSC-1234164 https://reactome.org/PathwayBrowser/#/R-SSC-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Sus scrofa 29033 R-SSC-1234165 https://reactome.org/PathwayBrowser/#/R-SSC-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 29033 R-SSC-1234173 https://reactome.org/PathwayBrowser/#/R-SSC-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 29033 R-SSC-1234177 https://reactome.org/PathwayBrowser/#/R-SSC-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 29033 R-SSC-1234181 https://reactome.org/PathwayBrowser/#/R-SSC-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 29033 R-SSC-1234183 https://reactome.org/PathwayBrowser/#/R-SSC-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Sus scrofa 29033 R-SSC-1237119 https://reactome.org/PathwayBrowser/#/R-SSC-1237119 Acireductone is oxidized to MOB IEA Sus scrofa 29033 R-SSC-1362408 https://reactome.org/PathwayBrowser/#/R-SSC-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Sus scrofa 29033 R-SSC-1362416 https://reactome.org/PathwayBrowser/#/R-SSC-1362416 Frataxin binds iron IEA Sus scrofa 29033 R-SSC-1562626 https://reactome.org/PathwayBrowser/#/R-SSC-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Sus scrofa 29033 R-SSC-1614645 https://reactome.org/PathwayBrowser/#/R-SSC-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Sus scrofa 29033 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa 29033 R-SSC-180038 https://reactome.org/PathwayBrowser/#/R-SSC-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function IEA Sus scrofa 29033 R-SSC-189398 https://reactome.org/PathwayBrowser/#/R-SSC-189398 HMOX1 dimer, HMOX2 cleave heme IEA Sus scrofa 29033 R-SSC-189465 https://reactome.org/PathwayBrowser/#/R-SSC-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Sus scrofa 29033 R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 29033 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa 29033 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa 29033 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa 29033 R-SSC-199803 https://reactome.org/PathwayBrowser/#/R-SSC-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Sus scrofa 29033 R-SSC-204662 https://reactome.org/PathwayBrowser/#/R-SSC-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Sus scrofa 29033 R-SSC-209823 https://reactome.org/PathwayBrowser/#/R-SSC-209823 Tyrosine is hydroxylated to dopa IEA Sus scrofa 29033 R-SSC-209828 https://reactome.org/PathwayBrowser/#/R-SSC-209828 Tryptophan is hydroxylated IEA Sus scrofa 29033 R-SSC-2161768 https://reactome.org/PathwayBrowser/#/R-SSC-2161768 EXA4 is converted to EXC4 by LTC4S IEA Sus scrofa 29033 R-SSC-2161775 https://reactome.org/PathwayBrowser/#/R-SSC-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Sus scrofa 29033 R-SSC-2161794 https://reactome.org/PathwayBrowser/#/R-SSC-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Sus scrofa 29033 R-SSC-2161907 https://reactome.org/PathwayBrowser/#/R-SSC-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Sus scrofa 29033 R-SSC-2161917 https://reactome.org/PathwayBrowser/#/R-SSC-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Sus scrofa 29033 R-SSC-2161948 https://reactome.org/PathwayBrowser/#/R-SSC-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Sus scrofa 29033 R-SSC-2161950 https://reactome.org/PathwayBrowser/#/R-SSC-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Sus scrofa 29033 R-SSC-2161964 https://reactome.org/PathwayBrowser/#/R-SSC-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Sus scrofa 29033 R-SSC-2162002 https://reactome.org/PathwayBrowser/#/R-SSC-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Sus scrofa 29033 R-SSC-2162019 https://reactome.org/PathwayBrowser/#/R-SSC-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Sus scrofa 29033 R-SSC-2162186 https://reactome.org/PathwayBrowser/#/R-SSC-2162186 COQ3 methylates DeMQ10H2 IEA Sus scrofa 29033 R-SSC-2162188 https://reactome.org/PathwayBrowser/#/R-SSC-2162188 COQ5 methylates MDMQ10H2 IEA Sus scrofa 29033 R-SSC-2162193 https://reactome.org/PathwayBrowser/#/R-SSC-2162193 COQ3 methylates DHDB IEA Sus scrofa 29033 R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa 29033 R-SSC-2172678 https://reactome.org/PathwayBrowser/#/R-SSC-2172678 PHF8 demethylates histone H4K20me1 IEA Sus scrofa 29033 R-SSC-2301205 https://reactome.org/PathwayBrowser/#/R-SSC-2301205 SETD8 monomethylates histone H4 IEA Sus scrofa 29033 R-SSC-265296 https://reactome.org/PathwayBrowser/#/R-SSC-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Sus scrofa 29033 R-SSC-266050 https://reactome.org/PathwayBrowser/#/R-SSC-266050 LTA4 is converted to LTC4 by LTC4S IEA Sus scrofa 29033 R-SSC-266051 https://reactome.org/PathwayBrowser/#/R-SSC-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Sus scrofa 29033 R-SSC-3222593 https://reactome.org/PathwayBrowser/#/R-SSC-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Sus scrofa 29033 R-SSC-389639 https://reactome.org/PathwayBrowser/#/R-SSC-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Sus scrofa 29033 R-SSC-428259 https://reactome.org/PathwayBrowser/#/R-SSC-428259 DEGS1 dehydrogenates dihydroceramide IEA Sus scrofa 29033 R-SSC-428260 https://reactome.org/PathwayBrowser/#/R-SSC-428260 DEGS2 oxygenates dihydroceramide IEA Sus scrofa 29033 R-SSC-429016 https://reactome.org/PathwayBrowser/#/R-SSC-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Sus scrofa 29033 R-SSC-435171 https://reactome.org/PathwayBrowser/#/R-SSC-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Sus scrofa 29033 R-SSC-435349 https://reactome.org/PathwayBrowser/#/R-SSC-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Sus scrofa 29033 R-SSC-442368 https://reactome.org/PathwayBrowser/#/R-SSC-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Sus scrofa 29033 R-SSC-5164399 https://reactome.org/PathwayBrowser/#/R-SSC-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Sus scrofa 29033 R-SSC-5678327 https://reactome.org/PathwayBrowser/#/R-SSC-5678327 MIOX oxidises Ins to GlcA IEA Sus scrofa 29033 R-SSC-5690873 https://reactome.org/PathwayBrowser/#/R-SSC-5690873 ACO1 binds 4Fe-4S IEA Sus scrofa 29033 R-SSC-5691107 https://reactome.org/PathwayBrowser/#/R-SSC-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Sus scrofa 29033 R-SSC-5693761 https://reactome.org/PathwayBrowser/#/R-SSC-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Sus scrofa 29033 R-SSC-6814153 https://reactome.org/PathwayBrowser/#/R-SSC-6814153 ADO oxidises 2AET to HTAU IEA Sus scrofa 29033 R-SSC-71118 https://reactome.org/PathwayBrowser/#/R-SSC-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Sus scrofa 29033 R-SSC-71163 https://reactome.org/PathwayBrowser/#/R-SSC-71163 HPD dioxygenates HPP IEA Sus scrofa 29033 R-SSC-71164 https://reactome.org/PathwayBrowser/#/R-SSC-71164 HGD dioxygenates homogentisate IEA Sus scrofa 29033 R-SSC-71218 https://reactome.org/PathwayBrowser/#/R-SSC-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Sus scrofa 29033 R-SSC-71241 https://reactome.org/PathwayBrowser/#/R-SSC-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Sus scrofa 29033 R-SSC-71261 https://reactome.org/PathwayBrowser/#/R-SSC-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Sus scrofa 29033 R-SSC-71303 https://reactome.org/PathwayBrowser/#/R-SSC-71303 RPE dimers isomerise RU5P to XY5P IEA Sus scrofa 29033 R-SSC-73815 https://reactome.org/PathwayBrowser/#/R-SSC-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Sus scrofa 29033 R-SSC-8857692 https://reactome.org/PathwayBrowser/#/R-SSC-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Sus scrofa 29033 R-SSC-8948219 https://reactome.org/PathwayBrowser/#/R-SSC-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Sus scrofa 29033 R-SSC-8948222 https://reactome.org/PathwayBrowser/#/R-SSC-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa 29033 R-SSC-8948224 https://reactome.org/PathwayBrowser/#/R-SSC-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa 29033 R-SSC-8948232 https://reactome.org/PathwayBrowser/#/R-SSC-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Sus scrofa 29033 R-SSC-8979071 https://reactome.org/PathwayBrowser/#/R-SSC-8979071 KDM6B binds iron IEA Sus scrofa 29033 R-SSC-9020274 https://reactome.org/PathwayBrowser/#/R-SSC-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Sus scrofa 29033 R-SSC-9024983 https://reactome.org/PathwayBrowser/#/R-SSC-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Sus scrofa 29033 R-SSC-9025957 https://reactome.org/PathwayBrowser/#/R-SSC-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Sus scrofa 29033 R-SSC-9026006 https://reactome.org/PathwayBrowser/#/R-SSC-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Sus scrofa 29033 R-SSC-9026007 https://reactome.org/PathwayBrowser/#/R-SSC-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Sus scrofa 29033 R-SSC-904830 https://reactome.org/PathwayBrowser/#/R-SSC-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Sus scrofa 29033 R-SSC-917805 https://reactome.org/PathwayBrowser/#/R-SSC-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Sus scrofa 29033 R-SSC-917811 https://reactome.org/PathwayBrowser/#/R-SSC-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Sus scrofa 29033 R-SSC-917891 https://reactome.org/PathwayBrowser/#/R-SSC-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Sus scrofa 29033 R-SSC-917933 https://reactome.org/PathwayBrowser/#/R-SSC-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Sus scrofa 29033 R-SSC-917936 https://reactome.org/PathwayBrowser/#/R-SSC-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Sus scrofa 29033 R-SSC-9629578 https://reactome.org/PathwayBrowser/#/R-SSC-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Sus scrofa 29033 R-SSC-9629591 https://reactome.org/PathwayBrowser/#/R-SSC-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Sus scrofa 29033 R-SSC-9629869 https://reactome.org/PathwayBrowser/#/R-SSC-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Sus scrofa 29033 R-SSC-9629888 https://reactome.org/PathwayBrowser/#/R-SSC-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Sus scrofa 29033 R-SSC-9629946 https://reactome.org/PathwayBrowser/#/R-SSC-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Sus scrofa 29033 R-SSC-9630022 https://reactome.org/PathwayBrowser/#/R-SSC-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Sus scrofa 29033 R-SSC-9630769 https://reactome.org/PathwayBrowser/#/R-SSC-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Sus scrofa 29033 R-SSC-9630967 https://reactome.org/PathwayBrowser/#/R-SSC-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Sus scrofa 29033 R-SSC-9630993 https://reactome.org/PathwayBrowser/#/R-SSC-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Sus scrofa 29033 R-SSC-9707186 https://reactome.org/PathwayBrowser/#/R-SSC-9707186 ALOX5 binds ALOX5 inhibitors IEA Sus scrofa 29033 R-SSC-975635 https://reactome.org/PathwayBrowser/#/R-SSC-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Sus scrofa 29033 R-SSC-9854368 https://reactome.org/PathwayBrowser/#/R-SSC-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Sus scrofa 29033 R-SSC-9854405 https://reactome.org/PathwayBrowser/#/R-SSC-9854405 Frataxin transfers Fe2+ to ACO2 IEA Sus scrofa 29033 R-SSC-9854984 https://reactome.org/PathwayBrowser/#/R-SSC-9854984 Transfer of Fe-S clusters to SDHB IEA Sus scrofa 29033 R-XTR-111285 https://reactome.org/PathwayBrowser/#/R-XTR-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Xenopus tropicalis 29033 R-XTR-111289 https://reactome.org/PathwayBrowser/#/R-XTR-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Xenopus tropicalis 29033 R-XTR-1234163 https://reactome.org/PathwayBrowser/#/R-XTR-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Xenopus tropicalis 29033 R-XTR-1234164 https://reactome.org/PathwayBrowser/#/R-XTR-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Xenopus tropicalis 29033 R-XTR-1234165 https://reactome.org/PathwayBrowser/#/R-XTR-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 29033 R-XTR-1234173 https://reactome.org/PathwayBrowser/#/R-XTR-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 29033 R-XTR-1234177 https://reactome.org/PathwayBrowser/#/R-XTR-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 29033 R-XTR-1234181 https://reactome.org/PathwayBrowser/#/R-XTR-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 29033 R-XTR-1234183 https://reactome.org/PathwayBrowser/#/R-XTR-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Xenopus tropicalis 29033 R-XTR-1237119 https://reactome.org/PathwayBrowser/#/R-XTR-1237119 Acireductone is oxidized to MOB IEA Xenopus tropicalis 29033 R-XTR-1362408 https://reactome.org/PathwayBrowser/#/R-XTR-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Xenopus tropicalis 29033 R-XTR-1362416 https://reactome.org/PathwayBrowser/#/R-XTR-1362416 Frataxin binds iron IEA Xenopus tropicalis 29033 R-XTR-1562626 https://reactome.org/PathwayBrowser/#/R-XTR-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Xenopus tropicalis 29033 R-XTR-1614645 https://reactome.org/PathwayBrowser/#/R-XTR-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Xenopus tropicalis 29033 R-XTR-1650808 https://reactome.org/PathwayBrowser/#/R-XTR-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Xenopus tropicalis 29033 R-XTR-189398 https://reactome.org/PathwayBrowser/#/R-XTR-189398 HMOX1 dimer, HMOX2 cleave heme IEA Xenopus tropicalis 29033 R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 29033 R-XTR-1980233 https://reactome.org/PathwayBrowser/#/R-XTR-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Xenopus tropicalis 29033 R-XTR-1981104 https://reactome.org/PathwayBrowser/#/R-XTR-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Xenopus tropicalis 29033 R-XTR-1981128 https://reactome.org/PathwayBrowser/#/R-XTR-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Xenopus tropicalis 29033 R-XTR-1981157 https://reactome.org/PathwayBrowser/#/R-XTR-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Xenopus tropicalis 29033 R-XTR-199803 https://reactome.org/PathwayBrowser/#/R-XTR-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Xenopus tropicalis 29033 R-XTR-204662 https://reactome.org/PathwayBrowser/#/R-XTR-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Xenopus tropicalis 29033 R-XTR-209823 https://reactome.org/PathwayBrowser/#/R-XTR-209823 Tyrosine is hydroxylated to dopa IEA Xenopus tropicalis 29033 R-XTR-2161768 https://reactome.org/PathwayBrowser/#/R-XTR-2161768 EXA4 is converted to EXC4 by LTC4S IEA Xenopus tropicalis 29033 R-XTR-2161907 https://reactome.org/PathwayBrowser/#/R-XTR-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Xenopus tropicalis 29033 R-XTR-2161917 https://reactome.org/PathwayBrowser/#/R-XTR-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Xenopus tropicalis 29033 R-XTR-2161950 https://reactome.org/PathwayBrowser/#/R-XTR-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Xenopus tropicalis 29033 R-XTR-2162002 https://reactome.org/PathwayBrowser/#/R-XTR-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Xenopus tropicalis 29033 R-XTR-2162186 https://reactome.org/PathwayBrowser/#/R-XTR-2162186 COQ3 methylates DeMQ10H2 IEA Xenopus tropicalis 29033 R-XTR-2162188 https://reactome.org/PathwayBrowser/#/R-XTR-2162188 COQ5 methylates MDMQ10H2 IEA Xenopus tropicalis 29033 R-XTR-2162193 https://reactome.org/PathwayBrowser/#/R-XTR-2162193 COQ3 methylates DHDB IEA Xenopus tropicalis 29033 R-XTR-2162194 https://reactome.org/PathwayBrowser/#/R-XTR-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Xenopus tropicalis 29033 R-XTR-2172678 https://reactome.org/PathwayBrowser/#/R-XTR-2172678 PHF8 demethylates histone H4K20me1 IEA Xenopus tropicalis 29033 R-XTR-2301205 https://reactome.org/PathwayBrowser/#/R-XTR-2301205 SETD8 monomethylates histone H4 IEA Xenopus tropicalis 29033 R-XTR-265296 https://reactome.org/PathwayBrowser/#/R-XTR-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Xenopus tropicalis 29033 R-XTR-266050 https://reactome.org/PathwayBrowser/#/R-XTR-266050 LTA4 is converted to LTC4 by LTC4S IEA Xenopus tropicalis 29033 R-XTR-266051 https://reactome.org/PathwayBrowser/#/R-XTR-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Xenopus tropicalis 29033 R-XTR-3222593 https://reactome.org/PathwayBrowser/#/R-XTR-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Xenopus tropicalis 29033 R-XTR-389639 https://reactome.org/PathwayBrowser/#/R-XTR-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Xenopus tropicalis 29033 R-XTR-428259 https://reactome.org/PathwayBrowser/#/R-XTR-428259 DEGS1 dehydrogenates dihydroceramide IEA Xenopus tropicalis 29033 R-XTR-428260 https://reactome.org/PathwayBrowser/#/R-XTR-428260 DEGS2 oxygenates dihydroceramide IEA Xenopus tropicalis 29033 R-XTR-435171 https://reactome.org/PathwayBrowser/#/R-XTR-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Xenopus tropicalis 29033 R-XTR-435349 https://reactome.org/PathwayBrowser/#/R-XTR-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Xenopus tropicalis 29033 R-XTR-442368 https://reactome.org/PathwayBrowser/#/R-XTR-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Xenopus tropicalis 29033 R-XTR-5164399 https://reactome.org/PathwayBrowser/#/R-XTR-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Xenopus tropicalis 29033 R-XTR-5690873 https://reactome.org/PathwayBrowser/#/R-XTR-5690873 ACO1 binds 4Fe-4S IEA Xenopus tropicalis 29033 R-XTR-5691107 https://reactome.org/PathwayBrowser/#/R-XTR-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Xenopus tropicalis 29033 R-XTR-5693761 https://reactome.org/PathwayBrowser/#/R-XTR-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Xenopus tropicalis 29033 R-XTR-6814153 https://reactome.org/PathwayBrowser/#/R-XTR-6814153 ADO oxidises 2AET to HTAU IEA Xenopus tropicalis 29033 R-XTR-71118 https://reactome.org/PathwayBrowser/#/R-XTR-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Xenopus tropicalis 29033 R-XTR-71163 https://reactome.org/PathwayBrowser/#/R-XTR-71163 HPD dioxygenates HPP IEA Xenopus tropicalis 29033 R-XTR-71218 https://reactome.org/PathwayBrowser/#/R-XTR-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Xenopus tropicalis 29033 R-XTR-71241 https://reactome.org/PathwayBrowser/#/R-XTR-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Xenopus tropicalis 29033 R-XTR-71261 https://reactome.org/PathwayBrowser/#/R-XTR-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Xenopus tropicalis 29033 R-XTR-71303 https://reactome.org/PathwayBrowser/#/R-XTR-71303 RPE dimers isomerise RU5P to XY5P IEA Xenopus tropicalis 29033 R-XTR-73815 https://reactome.org/PathwayBrowser/#/R-XTR-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Xenopus tropicalis 29033 R-XTR-8857692 https://reactome.org/PathwayBrowser/#/R-XTR-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Xenopus tropicalis 29033 R-XTR-8948219 https://reactome.org/PathwayBrowser/#/R-XTR-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Xenopus tropicalis 29033 R-XTR-8948222 https://reactome.org/PathwayBrowser/#/R-XTR-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Xenopus tropicalis 29033 R-XTR-8948224 https://reactome.org/PathwayBrowser/#/R-XTR-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Xenopus tropicalis 29033 R-XTR-8948232 https://reactome.org/PathwayBrowser/#/R-XTR-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Xenopus tropicalis 29033 R-XTR-8979071 https://reactome.org/PathwayBrowser/#/R-XTR-8979071 KDM6B binds iron IEA Xenopus tropicalis 29033 R-XTR-904830 https://reactome.org/PathwayBrowser/#/R-XTR-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Xenopus tropicalis 29033 R-XTR-917805 https://reactome.org/PathwayBrowser/#/R-XTR-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Xenopus tropicalis 29033 R-XTR-917811 https://reactome.org/PathwayBrowser/#/R-XTR-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Xenopus tropicalis 29033 R-XTR-917891 https://reactome.org/PathwayBrowser/#/R-XTR-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Xenopus tropicalis 29033 R-XTR-917933 https://reactome.org/PathwayBrowser/#/R-XTR-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Xenopus tropicalis 29033 R-XTR-917936 https://reactome.org/PathwayBrowser/#/R-XTR-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Xenopus tropicalis 29033 R-XTR-9629578 https://reactome.org/PathwayBrowser/#/R-XTR-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Xenopus tropicalis 29033 R-XTR-9629591 https://reactome.org/PathwayBrowser/#/R-XTR-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Xenopus tropicalis 29033 R-XTR-9629869 https://reactome.org/PathwayBrowser/#/R-XTR-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Xenopus tropicalis 29033 R-XTR-9629888 https://reactome.org/PathwayBrowser/#/R-XTR-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Xenopus tropicalis 29033 R-XTR-9630022 https://reactome.org/PathwayBrowser/#/R-XTR-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Xenopus tropicalis 29033 R-XTR-9630769 https://reactome.org/PathwayBrowser/#/R-XTR-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Xenopus tropicalis 29033 R-XTR-9630993 https://reactome.org/PathwayBrowser/#/R-XTR-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Xenopus tropicalis 29033 R-XTR-9707186 https://reactome.org/PathwayBrowser/#/R-XTR-9707186 ALOX5 binds ALOX5 inhibitors IEA Xenopus tropicalis 29033 R-XTR-975635 https://reactome.org/PathwayBrowser/#/R-XTR-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Xenopus tropicalis 29033 R-XTR-9854368 https://reactome.org/PathwayBrowser/#/R-XTR-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Xenopus tropicalis 29034 R-BTA-111742 https://reactome.org/PathwayBrowser/#/R-BTA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 29034 R-BTA-111751 https://reactome.org/PathwayBrowser/#/R-BTA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 29034 R-BTA-111804 https://reactome.org/PathwayBrowser/#/R-BTA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 29034 R-BTA-1222491 https://reactome.org/PathwayBrowser/#/R-BTA-1222491 Lactoferrin scavenges iron ions IEA Bos taurus 29034 R-BTA-2025890 https://reactome.org/PathwayBrowser/#/R-BTA-2025890 Calcineurin binds NFATC1,2,3 IEA Bos taurus 29034 R-BTA-2730849 https://reactome.org/PathwayBrowser/#/R-BTA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Bos taurus 29034 R-BTA-2730867 https://reactome.org/PathwayBrowser/#/R-BTA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Bos taurus 29034 R-BTA-2730872 https://reactome.org/PathwayBrowser/#/R-BTA-2730872 Activation of Calcineurin IEA Bos taurus 29034 R-BTA-375176 https://reactome.org/PathwayBrowser/#/R-BTA-375176 Inactive catalytic PP2B is activated by the binding of calmodulin TAS Bos taurus 29034 R-BTA-428259 https://reactome.org/PathwayBrowser/#/R-BTA-428259 DEGS1 dehydrogenates dihydroceramide IEA Bos taurus 29034 R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 29034 R-BTA-4551451 https://reactome.org/PathwayBrowser/#/R-BTA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Bos taurus 29034 R-BTA-4551465 https://reactome.org/PathwayBrowser/#/R-BTA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Bos taurus 29034 R-BTA-5229273 https://reactome.org/PathwayBrowser/#/R-BTA-5229273 LCN2:2,5DHBA binds Fe3+ IEA Bos taurus 29034 R-BTA-5671707 https://reactome.org/PathwayBrowser/#/R-BTA-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Bos taurus 29034 R-BTA-5691150 https://reactome.org/PathwayBrowser/#/R-BTA-5691150 TFR2 dimer binds 2xholoTF IEA Bos taurus 29034 R-BTA-5693761 https://reactome.org/PathwayBrowser/#/R-BTA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Bos taurus 29034 R-BTA-6793591 https://reactome.org/PathwayBrowser/#/R-BTA-6793591 LIAS synthesizes lipoyl-GCSH IEA Bos taurus 29034 R-BTA-8866277 https://reactome.org/PathwayBrowser/#/R-BTA-8866277 AP-2 directly binds some endocytic cargo IEA Bos taurus 29034 R-BTA-8866405 https://reactome.org/PathwayBrowser/#/R-BTA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 29034 R-BTA-8867754 https://reactome.org/PathwayBrowser/#/R-BTA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Bos taurus 29034 R-BTA-8867756 https://reactome.org/PathwayBrowser/#/R-BTA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Bos taurus 29034 R-BTA-8868071 https://reactome.org/PathwayBrowser/#/R-BTA-8868071 Clathrin recruits PIK3C2A IEA Bos taurus 29034 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 29034 R-BTA-8868230 https://reactome.org/PathwayBrowser/#/R-BTA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Bos taurus 29034 R-BTA-8868236 https://reactome.org/PathwayBrowser/#/R-BTA-8868236 BAR domain proteins recruit dynamin IEA Bos taurus 29034 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 29034 R-BTA-8868651 https://reactome.org/PathwayBrowser/#/R-BTA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Bos taurus 29034 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 29034 R-BTA-8868659 https://reactome.org/PathwayBrowser/#/R-BTA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Bos taurus 29034 R-BTA-8868660 https://reactome.org/PathwayBrowser/#/R-BTA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Bos taurus 29034 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 29034 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 29034 R-BTA-8871194 https://reactome.org/PathwayBrowser/#/R-BTA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Bos taurus 29034 R-BTA-917805 https://reactome.org/PathwayBrowser/#/R-BTA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Bos taurus 29034 R-BTA-917807 https://reactome.org/PathwayBrowser/#/R-BTA-917807 holoTF:TFRC dimer translocates from plasma membrane to endosome membrane IEA Bos taurus 29034 R-BTA-917811 https://reactome.org/PathwayBrowser/#/R-BTA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Bos taurus 29034 R-BTA-917835 https://reactome.org/PathwayBrowser/#/R-BTA-917835 Fe3+ dissociates from holoTF:TFRC dimer IEA Bos taurus 29034 R-BTA-917888 https://reactome.org/PathwayBrowser/#/R-BTA-917888 apoTF binds 2Fe3+ to form holoTF IEA Bos taurus 29034 R-BTA-917891 https://reactome.org/PathwayBrowser/#/R-BTA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Bos taurus 29034 R-BTA-917933 https://reactome.org/PathwayBrowser/#/R-BTA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Bos taurus 29034 R-BTA-917987 https://reactome.org/PathwayBrowser/#/R-BTA-917987 TFRC dimer binds 2xholoTF IEA Bos taurus 29034 R-CEL-111742 https://reactome.org/PathwayBrowser/#/R-CEL-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 29034 R-CEL-111751 https://reactome.org/PathwayBrowser/#/R-CEL-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 29034 R-CEL-111804 https://reactome.org/PathwayBrowser/#/R-CEL-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 29034 R-CEL-2730867 https://reactome.org/PathwayBrowser/#/R-CEL-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Caenorhabditis elegans 29034 R-CEL-2730872 https://reactome.org/PathwayBrowser/#/R-CEL-2730872 Activation of Calcineurin IEA Caenorhabditis elegans 29034 R-CEL-428259 https://reactome.org/PathwayBrowser/#/R-CEL-428259 DEGS1 dehydrogenates dihydroceramide IEA Caenorhabditis elegans 29034 R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 29034 R-CEL-4551465 https://reactome.org/PathwayBrowser/#/R-CEL-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Caenorhabditis elegans 29034 R-CEL-5693761 https://reactome.org/PathwayBrowser/#/R-CEL-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Caenorhabditis elegans 29034 R-CEL-8866405 https://reactome.org/PathwayBrowser/#/R-CEL-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 29034 R-CEL-917805 https://reactome.org/PathwayBrowser/#/R-CEL-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Caenorhabditis elegans 29034 R-CFA-111742 https://reactome.org/PathwayBrowser/#/R-CFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 29034 R-CFA-111751 https://reactome.org/PathwayBrowser/#/R-CFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 29034 R-CFA-111804 https://reactome.org/PathwayBrowser/#/R-CFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 29034 R-CFA-1222491 https://reactome.org/PathwayBrowser/#/R-CFA-1222491 Lactoferrin scavenges iron ions IEA Canis familiaris 29034 R-CFA-2025890 https://reactome.org/PathwayBrowser/#/R-CFA-2025890 Calcineurin binds NFATC1,2,3 IEA Canis familiaris 29034 R-CFA-2730849 https://reactome.org/PathwayBrowser/#/R-CFA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Canis familiaris 29034 R-CFA-2730867 https://reactome.org/PathwayBrowser/#/R-CFA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Canis familiaris 29034 R-CFA-2730872 https://reactome.org/PathwayBrowser/#/R-CFA-2730872 Activation of Calcineurin IEA Canis familiaris 29034 R-CFA-428259 https://reactome.org/PathwayBrowser/#/R-CFA-428259 DEGS1 dehydrogenates dihydroceramide IEA Canis familiaris 29034 R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 29034 R-CFA-4551451 https://reactome.org/PathwayBrowser/#/R-CFA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Canis familiaris 29034 R-CFA-4551465 https://reactome.org/PathwayBrowser/#/R-CFA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Canis familiaris 29034 R-CFA-5229273 https://reactome.org/PathwayBrowser/#/R-CFA-5229273 LCN2:2,5DHBA binds Fe3+ IEA Canis familiaris 29034 R-CFA-5671707 https://reactome.org/PathwayBrowser/#/R-CFA-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Canis familiaris 29034 R-CFA-5693761 https://reactome.org/PathwayBrowser/#/R-CFA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Canis familiaris 29034 R-CFA-6793591 https://reactome.org/PathwayBrowser/#/R-CFA-6793591 LIAS synthesizes lipoyl-GCSH IEA Canis familiaris 29034 R-CFA-8866405 https://reactome.org/PathwayBrowser/#/R-CFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 29034 R-CFA-917805 https://reactome.org/PathwayBrowser/#/R-CFA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Canis familiaris 29034 R-CFA-917811 https://reactome.org/PathwayBrowser/#/R-CFA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Canis familiaris 29034 R-CFA-917891 https://reactome.org/PathwayBrowser/#/R-CFA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Canis familiaris 29034 R-CFA-917933 https://reactome.org/PathwayBrowser/#/R-CFA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Canis familiaris 29034 R-DDI-111751 https://reactome.org/PathwayBrowser/#/R-DDI-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 29034 R-DDI-111804 https://reactome.org/PathwayBrowser/#/R-DDI-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 29034 R-DDI-2730867 https://reactome.org/PathwayBrowser/#/R-DDI-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Dictyostelium discoideum 29034 R-DDI-2730872 https://reactome.org/PathwayBrowser/#/R-DDI-2730872 Activation of Calcineurin IEA Dictyostelium discoideum 29034 R-DDI-428259 https://reactome.org/PathwayBrowser/#/R-DDI-428259 DEGS1 dehydrogenates dihydroceramide IEA Dictyostelium discoideum 29034 R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 29034 R-DDI-4551465 https://reactome.org/PathwayBrowser/#/R-DDI-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Dictyostelium discoideum 29034 R-DDI-5693761 https://reactome.org/PathwayBrowser/#/R-DDI-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Dictyostelium discoideum 29034 R-DME-111751 https://reactome.org/PathwayBrowser/#/R-DME-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 29034 R-DME-111804 https://reactome.org/PathwayBrowser/#/R-DME-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 29034 R-DME-1222491 https://reactome.org/PathwayBrowser/#/R-DME-1222491 Lactoferrin scavenges iron ions IEA Drosophila melanogaster 29034 R-DME-2025890 https://reactome.org/PathwayBrowser/#/R-DME-2025890 Calcineurin binds NFATC1,2,3 IEA Drosophila melanogaster 29034 R-DME-2730849 https://reactome.org/PathwayBrowser/#/R-DME-2730849 Calcineurin binds and dephosphorylates NFAT IEA Drosophila melanogaster 29034 R-DME-2730867 https://reactome.org/PathwayBrowser/#/R-DME-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Drosophila melanogaster 29034 R-DME-2730872 https://reactome.org/PathwayBrowser/#/R-DME-2730872 Activation of Calcineurin IEA Drosophila melanogaster 29034 R-DME-428259 https://reactome.org/PathwayBrowser/#/R-DME-428259 DEGS1 dehydrogenates dihydroceramide IEA Drosophila melanogaster 29034 R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 29034 R-DME-4551451 https://reactome.org/PathwayBrowser/#/R-DME-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Drosophila melanogaster 29034 R-DME-4551465 https://reactome.org/PathwayBrowser/#/R-DME-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Drosophila melanogaster 29034 R-DME-5229273 https://reactome.org/PathwayBrowser/#/R-DME-5229273 LCN2:2,5DHBA binds Fe3+ IEA Drosophila melanogaster 29034 R-DME-5671707 https://reactome.org/PathwayBrowser/#/R-DME-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Drosophila melanogaster 29034 R-DME-5693761 https://reactome.org/PathwayBrowser/#/R-DME-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Drosophila melanogaster 29034 R-DME-6793591 https://reactome.org/PathwayBrowser/#/R-DME-6793591 LIAS synthesizes lipoyl-GCSH IEA Drosophila melanogaster 29034 R-DME-917805 https://reactome.org/PathwayBrowser/#/R-DME-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Drosophila melanogaster 29034 R-DME-917888 https://reactome.org/PathwayBrowser/#/R-DME-917888 apoTF binds 2Fe3+ to form holoTF IEA Drosophila melanogaster 29034 R-DRE-111742 https://reactome.org/PathwayBrowser/#/R-DRE-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 29034 R-DRE-111751 https://reactome.org/PathwayBrowser/#/R-DRE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 29034 R-DRE-111804 https://reactome.org/PathwayBrowser/#/R-DRE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 29034 R-DRE-428259 https://reactome.org/PathwayBrowser/#/R-DRE-428259 DEGS1 dehydrogenates dihydroceramide IEA Danio rerio 29034 R-DRE-5229273 https://reactome.org/PathwayBrowser/#/R-DRE-5229273 LCN2:2,5DHBA binds Fe3+ IEA Danio rerio 29034 R-DRE-6793591 https://reactome.org/PathwayBrowser/#/R-DRE-6793591 LIAS synthesizes lipoyl-GCSH IEA Danio rerio 29034 R-DRE-8866405 https://reactome.org/PathwayBrowser/#/R-DRE-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 29034 R-DRE-917805 https://reactome.org/PathwayBrowser/#/R-DRE-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Danio rerio 29034 R-DRE-917891 https://reactome.org/PathwayBrowser/#/R-DRE-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Danio rerio 29034 R-GGA-1222491 https://reactome.org/PathwayBrowser/#/R-GGA-1222491 Lactoferrin scavenges iron ions IEA Gallus gallus 29034 R-GGA-2025890 https://reactome.org/PathwayBrowser/#/R-GGA-2025890 Calcineurin binds NFATC1,2,3 IEA Gallus gallus 29034 R-GGA-2730849 https://reactome.org/PathwayBrowser/#/R-GGA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Gallus gallus 29034 R-GGA-2730867 https://reactome.org/PathwayBrowser/#/R-GGA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Gallus gallus 29034 R-GGA-2730872 https://reactome.org/PathwayBrowser/#/R-GGA-2730872 Activation of Calcineurin IEA Gallus gallus 29034 R-GGA-428259 https://reactome.org/PathwayBrowser/#/R-GGA-428259 DEGS1 dehydrogenates dihydroceramide IEA Gallus gallus 29034 R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 29034 R-GGA-4551451 https://reactome.org/PathwayBrowser/#/R-GGA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Gallus gallus 29034 R-GGA-4551465 https://reactome.org/PathwayBrowser/#/R-GGA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Gallus gallus 29034 R-GGA-5229273 https://reactome.org/PathwayBrowser/#/R-GGA-5229273 LCN2:2,5DHBA binds Fe3+ IEA Gallus gallus 29034 R-GGA-5693761 https://reactome.org/PathwayBrowser/#/R-GGA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Gallus gallus 29034 R-GGA-6793591 https://reactome.org/PathwayBrowser/#/R-GGA-6793591 LIAS synthesizes lipoyl-GCSH IEA Gallus gallus 29034 R-GGA-8866277 https://reactome.org/PathwayBrowser/#/R-GGA-8866277 AP-2 directly binds some endocytic cargo IEA Gallus gallus 29034 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus 29034 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus 29034 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus 29034 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus 29034 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus 29034 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus 29034 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus 29034 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus 29034 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus 29034 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus 29034 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus 29034 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus 29034 R-GGA-917805 https://reactome.org/PathwayBrowser/#/R-GGA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Gallus gallus 29034 R-GGA-917807 https://reactome.org/PathwayBrowser/#/R-GGA-917807 holoTF:TFRC dimer translocates from plasma membrane to endosome membrane IEA Gallus gallus 29034 R-GGA-917811 https://reactome.org/PathwayBrowser/#/R-GGA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Gallus gallus 29034 R-GGA-917835 https://reactome.org/PathwayBrowser/#/R-GGA-917835 Fe3+ dissociates from holoTF:TFRC dimer IEA Gallus gallus 29034 R-GGA-917888 https://reactome.org/PathwayBrowser/#/R-GGA-917888 apoTF binds 2Fe3+ to form holoTF IEA Gallus gallus 29034 R-GGA-917891 https://reactome.org/PathwayBrowser/#/R-GGA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Gallus gallus 29034 R-GGA-917933 https://reactome.org/PathwayBrowser/#/R-GGA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Gallus gallus 29034 R-GGA-917987 https://reactome.org/PathwayBrowser/#/R-GGA-917987 TFRC dimer binds 2xholoTF IEA Gallus gallus 29034 R-HSA-111742 https://reactome.org/PathwayBrowser/#/R-HSA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 29034 R-HSA-111751 https://reactome.org/PathwayBrowser/#/R-HSA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 29034 R-HSA-111804 https://reactome.org/PathwayBrowser/#/R-HSA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 29034 R-HSA-1222325 https://reactome.org/PathwayBrowser/#/R-HSA-1222325 Carboxymycobactin and mycobactin exchange their iron load TAS Homo sapiens 29034 R-HSA-1222399 https://reactome.org/PathwayBrowser/#/R-HSA-1222399 Iron is reduced and separates from mycobactin IEA Homo sapiens 29034 R-HSA-1222491 https://reactome.org/PathwayBrowser/#/R-HSA-1222491 Lactoferrin scavenges iron ions TAS Homo sapiens 29034 R-HSA-1222597 https://reactome.org/PathwayBrowser/#/R-HSA-1222597 Loaded mycobactin gets imported TAS Homo sapiens 29034 R-HSA-1222641 https://reactome.org/PathwayBrowser/#/R-HSA-1222641 Carboxymycobactin binds LTF:2xFe3+:2xCO3(2-) TAS Homo sapiens 29034 R-HSA-1497883 https://reactome.org/PathwayBrowser/#/R-HSA-1497883 Ferrous iron reduces the BH3 radical back to BH4 TAS Homo sapiens 29034 R-HSA-1562603 https://reactome.org/PathwayBrowser/#/R-HSA-1562603 BfrB stores iron TAS Homo sapiens 29034 R-HSA-1562604 https://reactome.org/PathwayBrowser/#/R-HSA-1562604 BfrA stores iron TAS Homo sapiens 29034 R-HSA-201783 https://reactome.org/PathwayBrowser/#/R-HSA-201783 Inactive catalytic PP2B is activated by the binding of calmodulin IEA Homo sapiens 29034 R-HSA-201787 https://reactome.org/PathwayBrowser/#/R-HSA-201787 PPP3 complex dephosphorylates DARPP-32 on Thr34 IEA Homo sapiens 29034 R-HSA-2025882 https://reactome.org/PathwayBrowser/#/R-HSA-2025882 Calcineurin dephosphorylates NFATC1,2,3 IEA Homo sapiens 29034 R-HSA-2025890 https://reactome.org/PathwayBrowser/#/R-HSA-2025890 Calcineurin binds NFATC1,2,3 TAS Homo sapiens 29034 R-HSA-2187266 https://reactome.org/PathwayBrowser/#/R-HSA-2187266 SCARA5 binds ligands IEA Homo sapiens 29034 R-HSA-2299677 https://reactome.org/PathwayBrowser/#/R-HSA-2299677 SCARA5:ligand is endocytosed IEA Homo sapiens 29034 R-HSA-2730849 https://reactome.org/PathwayBrowser/#/R-HSA-2730849 Calcineurin binds and dephosphorylates NFAT TAS Homo sapiens 29034 R-HSA-2730867 https://reactome.org/PathwayBrowser/#/R-HSA-2730867 Translocation of CaN:CaM:NFAT to nucleus TAS Homo sapiens 29034 R-HSA-2730872 https://reactome.org/PathwayBrowser/#/R-HSA-2730872 Activation of Calcineurin TAS Homo sapiens 29034 R-HSA-428259 https://reactome.org/PathwayBrowser/#/R-HSA-428259 DEGS1 dehydrogenates dihydroceramide TAS Homo sapiens 29034 R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 29034 R-HSA-4551451 https://reactome.org/PathwayBrowser/#/R-HSA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling TAS Homo sapiens 29034 R-HSA-4551465 https://reactome.org/PathwayBrowser/#/R-HSA-4551465 Translocation of NFATC1:CaN:CaM to nucleus TAS Homo sapiens 29034 R-HSA-5229273 https://reactome.org/PathwayBrowser/#/R-HSA-5229273 LCN2:2,5DHBA binds Fe3+ TAS Homo sapiens 29034 R-HSA-5246444 https://reactome.org/PathwayBrowser/#/R-HSA-5246444 SLC22A17 binds LCN2:2,5DHBA:Fe3+ IEA Homo sapiens 29034 R-HSA-5655760 https://reactome.org/PathwayBrowser/#/R-HSA-5655760 Defective SLC40A1 does not transport Fe3+ from extracellular region to cytosol TAS Homo sapiens 29034 R-HSA-5671707 https://reactome.org/PathwayBrowser/#/R-HSA-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA TAS Homo sapiens 29034 R-HSA-5691150 https://reactome.org/PathwayBrowser/#/R-HSA-5691150 TFR2 dimer binds 2xholoTF TAS Homo sapiens 29034 R-HSA-5693761 https://reactome.org/PathwayBrowser/#/R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids TAS Homo sapiens 29034 R-HSA-6789160 https://reactome.org/PathwayBrowser/#/R-HSA-6789160 Hydrogen peroxide and Fe2+ react to hydroxyl, hydroxide and Fe3+ TAS Homo sapiens 29034 R-HSA-6793591 https://reactome.org/PathwayBrowser/#/R-HSA-6793591 LIAS synthesizes lipoyl-GCSH TAS Homo sapiens 29034 R-HSA-76494 https://reactome.org/PathwayBrowser/#/R-HSA-76494 POR reduces CYP450:Fe3+ to CYP450:Fe2+ TAS Homo sapiens 29034 R-HSA-8866277 https://reactome.org/PathwayBrowser/#/R-HSA-8866277 AP-2 directly binds some endocytic cargo TAS Homo sapiens 29034 R-HSA-8866405 https://reactome.org/PathwayBrowser/#/R-HSA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 29034 R-HSA-8867754 https://reactome.org/PathwayBrowser/#/R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit TAS Homo sapiens 29034 R-HSA-8867756 https://reactome.org/PathwayBrowser/#/R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit TAS Homo sapiens 29034 R-HSA-8868071 https://reactome.org/PathwayBrowser/#/R-HSA-8868071 Clathrin recruits PIK3C2A TAS Homo sapiens 29034 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 29034 R-HSA-8868230 https://reactome.org/PathwayBrowser/#/R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery TAS Homo sapiens 29034 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 29034 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 29034 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 29034 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 29034 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 29034 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 29034 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 29034 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 29034 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 29034 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 29034 R-HSA-8951549 https://reactome.org/PathwayBrowser/#/R-HSA-8951549 Carbocymycobactin binds Fe3+ from LTF:2xFe3+:2xCO3(2-) TAS Homo sapiens 29034 R-HSA-8951552 https://reactome.org/PathwayBrowser/#/R-HSA-8951552 LTF:2xCO3(2-) dissociates from Carbocymycobactin:Fe3+ TAS Homo sapiens 29034 R-HSA-917805 https://reactome.org/PathwayBrowser/#/R-HSA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ TAS Homo sapiens 29034 R-HSA-917807 https://reactome.org/PathwayBrowser/#/R-HSA-917807 holoTF:TFRC dimer translocates from plasma membrane to endosome membrane TAS Homo sapiens 29034 R-HSA-917811 https://reactome.org/PathwayBrowser/#/R-HSA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ TAS Homo sapiens 29034 R-HSA-917835 https://reactome.org/PathwayBrowser/#/R-HSA-917835 Fe3+ dissociates from holoTF:TFRC dimer TAS Homo sapiens 29034 R-HSA-917888 https://reactome.org/PathwayBrowser/#/R-HSA-917888 apoTF binds 2Fe3+ to form holoTF TAS Homo sapiens 29034 R-HSA-917891 https://reactome.org/PathwayBrowser/#/R-HSA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ TAS Homo sapiens 29034 R-HSA-917933 https://reactome.org/PathwayBrowser/#/R-HSA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ TAS Homo sapiens 29034 R-HSA-917987 https://reactome.org/PathwayBrowser/#/R-HSA-917987 TFRC dimer binds 2xholoTF TAS Homo sapiens 29034 R-MMU-111742 https://reactome.org/PathwayBrowser/#/R-MMU-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 29034 R-MMU-111751 https://reactome.org/PathwayBrowser/#/R-MMU-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 29034 R-MMU-111804 https://reactome.org/PathwayBrowser/#/R-MMU-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 29034 R-MMU-1222491 https://reactome.org/PathwayBrowser/#/R-MMU-1222491 Lactoferrin scavenges iron ions IEA Mus musculus 29034 R-MMU-2025890 https://reactome.org/PathwayBrowser/#/R-MMU-2025890 Calcineurin binds NFATC1,2,3 IEA Mus musculus 29034 R-MMU-2025936 https://reactome.org/PathwayBrowser/#/R-MMU-2025936 Calcineurin Dephosphorylates Nfatc2 TAS Mus musculus 29034 R-MMU-2187267 https://reactome.org/PathwayBrowser/#/R-MMU-2187267 Scara5 binds ligands TAS Mus musculus 29034 R-MMU-2507848 https://reactome.org/PathwayBrowser/#/R-MMU-2507848 Endocytosis of Scara5:Ferritin TAS Mus musculus 29034 R-MMU-2730849 https://reactome.org/PathwayBrowser/#/R-MMU-2730849 Calcineurin binds and dephosphorylates NFAT IEA Mus musculus 29034 R-MMU-2730867 https://reactome.org/PathwayBrowser/#/R-MMU-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Mus musculus 29034 R-MMU-2730872 https://reactome.org/PathwayBrowser/#/R-MMU-2730872 Activation of Calcineurin IEA Mus musculus 29034 R-MMU-428259 https://reactome.org/PathwayBrowser/#/R-MMU-428259 DEGS1 dehydrogenates dihydroceramide IEA Mus musculus 29034 R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 29034 R-MMU-4551451 https://reactome.org/PathwayBrowser/#/R-MMU-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Mus musculus 29034 R-MMU-4551465 https://reactome.org/PathwayBrowser/#/R-MMU-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Mus musculus 29034 R-MMU-5229273 https://reactome.org/PathwayBrowser/#/R-MMU-5229273 LCN2:2,5DHBA binds Fe3+ IEA Mus musculus 29034 R-MMU-5246466 https://reactome.org/PathwayBrowser/#/R-MMU-5246466 Slc22a17 binds Lcn2, internalising it, releasing Fe3+ TAS Mus musculus 29034 R-MMU-5671707 https://reactome.org/PathwayBrowser/#/R-MMU-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Mus musculus 29034 R-MMU-5691150 https://reactome.org/PathwayBrowser/#/R-MMU-5691150 TFR2 dimer binds 2xholoTF IEA Mus musculus 29034 R-MMU-5693761 https://reactome.org/PathwayBrowser/#/R-MMU-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Mus musculus 29034 R-MMU-6793591 https://reactome.org/PathwayBrowser/#/R-MMU-6793591 LIAS synthesizes lipoyl-GCSH IEA Mus musculus 29034 R-MMU-8866277 https://reactome.org/PathwayBrowser/#/R-MMU-8866277 AP-2 directly binds some endocytic cargo IEA Mus musculus 29034 R-MMU-8866405 https://reactome.org/PathwayBrowser/#/R-MMU-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 29034 R-MMU-8867754 https://reactome.org/PathwayBrowser/#/R-MMU-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Mus musculus 29034 R-MMU-8867756 https://reactome.org/PathwayBrowser/#/R-MMU-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Mus musculus 29034 R-MMU-8868071 https://reactome.org/PathwayBrowser/#/R-MMU-8868071 Clathrin recruits PIK3C2A IEA Mus musculus 29034 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 29034 R-MMU-8868236 https://reactome.org/PathwayBrowser/#/R-MMU-8868236 BAR domain proteins recruit dynamin IEA Mus musculus 29034 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 29034 R-MMU-8868651 https://reactome.org/PathwayBrowser/#/R-MMU-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Mus musculus 29034 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 29034 R-MMU-8868659 https://reactome.org/PathwayBrowser/#/R-MMU-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Mus musculus 29034 R-MMU-8868660 https://reactome.org/PathwayBrowser/#/R-MMU-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Mus musculus 29034 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 29034 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 29034 R-MMU-8871194 https://reactome.org/PathwayBrowser/#/R-MMU-8871194 RAB5 and GAPVD1 bind AP-2 IEA Mus musculus 29034 R-MMU-917805 https://reactome.org/PathwayBrowser/#/R-MMU-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Mus musculus 29034 R-MMU-917807 https://reactome.org/PathwayBrowser/#/R-MMU-917807 holoTF:TFRC dimer translocates from plasma membrane to endosome membrane IEA Mus musculus 29034 R-MMU-917811 https://reactome.org/PathwayBrowser/#/R-MMU-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Mus musculus 29034 R-MMU-917835 https://reactome.org/PathwayBrowser/#/R-MMU-917835 Fe3+ dissociates from holoTF:TFRC dimer IEA Mus musculus 29034 R-MMU-917888 https://reactome.org/PathwayBrowser/#/R-MMU-917888 apoTF binds 2Fe3+ to form holoTF IEA Mus musculus 29034 R-MMU-917891 https://reactome.org/PathwayBrowser/#/R-MMU-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Mus musculus 29034 R-MMU-917933 https://reactome.org/PathwayBrowser/#/R-MMU-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Mus musculus 29034 R-MMU-917987 https://reactome.org/PathwayBrowser/#/R-MMU-917987 TFRC dimer binds 2xholoTF IEA Mus musculus 29034 R-PFA-111742 https://reactome.org/PathwayBrowser/#/R-PFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 29034 R-PFA-111751 https://reactome.org/PathwayBrowser/#/R-PFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 29034 R-PFA-111804 https://reactome.org/PathwayBrowser/#/R-PFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 29034 R-PFA-2730867 https://reactome.org/PathwayBrowser/#/R-PFA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Plasmodium falciparum 29034 R-PFA-2730872 https://reactome.org/PathwayBrowser/#/R-PFA-2730872 Activation of Calcineurin IEA Plasmodium falciparum 29034 R-PFA-4551465 https://reactome.org/PathwayBrowser/#/R-PFA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Plasmodium falciparum 29034 R-PFA-8866405 https://reactome.org/PathwayBrowser/#/R-PFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 29034 R-RNO-111742 https://reactome.org/PathwayBrowser/#/R-RNO-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 29034 R-RNO-111751 https://reactome.org/PathwayBrowser/#/R-RNO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 29034 R-RNO-111804 https://reactome.org/PathwayBrowser/#/R-RNO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 29034 R-RNO-1222491 https://reactome.org/PathwayBrowser/#/R-RNO-1222491 Lactoferrin scavenges iron ions IEA Rattus norvegicus 29034 R-RNO-201760 https://reactome.org/PathwayBrowser/#/R-RNO-201760 Ppp3 complex dephosphorylates DARPP-32 on T34 TAS Rattus norvegicus 29034 R-RNO-2025890 https://reactome.org/PathwayBrowser/#/R-RNO-2025890 Calcineurin binds NFATC1,2,3 IEA Rattus norvegicus 29034 R-RNO-2730849 https://reactome.org/PathwayBrowser/#/R-RNO-2730849 Calcineurin binds and dephosphorylates NFAT IEA Rattus norvegicus 29034 R-RNO-2730867 https://reactome.org/PathwayBrowser/#/R-RNO-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Rattus norvegicus 29034 R-RNO-2730872 https://reactome.org/PathwayBrowser/#/R-RNO-2730872 Activation of Calcineurin IEA Rattus norvegicus 29034 R-RNO-428259 https://reactome.org/PathwayBrowser/#/R-RNO-428259 DEGS1 dehydrogenates dihydroceramide IEA Rattus norvegicus 29034 R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 29034 R-RNO-4551451 https://reactome.org/PathwayBrowser/#/R-RNO-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Rattus norvegicus 29034 R-RNO-4551465 https://reactome.org/PathwayBrowser/#/R-RNO-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Rattus norvegicus 29034 R-RNO-5229273 https://reactome.org/PathwayBrowser/#/R-RNO-5229273 LCN2:2,5DHBA binds Fe3+ IEA Rattus norvegicus 29034 R-RNO-5671707 https://reactome.org/PathwayBrowser/#/R-RNO-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Rattus norvegicus 29034 R-RNO-5691150 https://reactome.org/PathwayBrowser/#/R-RNO-5691150 TFR2 dimer binds 2xholoTF IEA Rattus norvegicus 29034 R-RNO-5693761 https://reactome.org/PathwayBrowser/#/R-RNO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Rattus norvegicus 29034 R-RNO-6793591 https://reactome.org/PathwayBrowser/#/R-RNO-6793591 LIAS synthesizes lipoyl-GCSH IEA Rattus norvegicus 29034 R-RNO-8866277 https://reactome.org/PathwayBrowser/#/R-RNO-8866277 AP-2 directly binds some endocytic cargo IEA Rattus norvegicus 29034 R-RNO-8866405 https://reactome.org/PathwayBrowser/#/R-RNO-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 29034 R-RNO-8867754 https://reactome.org/PathwayBrowser/#/R-RNO-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Rattus norvegicus 29034 R-RNO-8867756 https://reactome.org/PathwayBrowser/#/R-RNO-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Rattus norvegicus 29034 R-RNO-8868071 https://reactome.org/PathwayBrowser/#/R-RNO-8868071 Clathrin recruits PIK3C2A IEA Rattus norvegicus 29034 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 29034 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus 29034 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 29034 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus 29034 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 29034 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus 29034 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus 29034 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 29034 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 29034 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus 29034 R-RNO-917805 https://reactome.org/PathwayBrowser/#/R-RNO-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Rattus norvegicus 29034 R-RNO-917807 https://reactome.org/PathwayBrowser/#/R-RNO-917807 holoTF:TFRC dimer translocates from plasma membrane to endosome membrane IEA Rattus norvegicus 29034 R-RNO-917811 https://reactome.org/PathwayBrowser/#/R-RNO-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Rattus norvegicus 29034 R-RNO-917835 https://reactome.org/PathwayBrowser/#/R-RNO-917835 Fe3+ dissociates from holoTF:TFRC dimer IEA Rattus norvegicus 29034 R-RNO-917888 https://reactome.org/PathwayBrowser/#/R-RNO-917888 apoTF binds 2Fe3+ to form holoTF IEA Rattus norvegicus 29034 R-RNO-917891 https://reactome.org/PathwayBrowser/#/R-RNO-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Rattus norvegicus 29034 R-RNO-917933 https://reactome.org/PathwayBrowser/#/R-RNO-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Rattus norvegicus 29034 R-RNO-917987 https://reactome.org/PathwayBrowser/#/R-RNO-917987 TFRC dimer binds 2xholoTF IEA Rattus norvegicus 29034 R-SCE-111751 https://reactome.org/PathwayBrowser/#/R-SCE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 29034 R-SCE-111804 https://reactome.org/PathwayBrowser/#/R-SCE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 29034 R-SCE-5693761 https://reactome.org/PathwayBrowser/#/R-SCE-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Saccharomyces cerevisiae 29034 R-SPO-111751 https://reactome.org/PathwayBrowser/#/R-SPO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 29034 R-SPO-111804 https://reactome.org/PathwayBrowser/#/R-SPO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 29034 R-SPO-2730867 https://reactome.org/PathwayBrowser/#/R-SPO-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Schizosaccharomyces pombe 29034 R-SPO-2730872 https://reactome.org/PathwayBrowser/#/R-SPO-2730872 Activation of Calcineurin IEA Schizosaccharomyces pombe 29034 R-SPO-428259 https://reactome.org/PathwayBrowser/#/R-SPO-428259 DEGS1 dehydrogenates dihydroceramide IEA Schizosaccharomyces pombe 29034 R-SPO-428260 https://reactome.org/PathwayBrowser/#/R-SPO-428260 DEGS2 oxygenates dihydroceramide IEA Schizosaccharomyces pombe 29034 R-SPO-4551465 https://reactome.org/PathwayBrowser/#/R-SPO-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Schizosaccharomyces pombe 29034 R-SPO-5693761 https://reactome.org/PathwayBrowser/#/R-SPO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Schizosaccharomyces pombe 29034 R-SSC-111742 https://reactome.org/PathwayBrowser/#/R-SSC-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 29034 R-SSC-111751 https://reactome.org/PathwayBrowser/#/R-SSC-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 29034 R-SSC-111804 https://reactome.org/PathwayBrowser/#/R-SSC-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 29034 R-SSC-1222491 https://reactome.org/PathwayBrowser/#/R-SSC-1222491 Lactoferrin scavenges iron ions IEA Sus scrofa 29034 R-SSC-2025890 https://reactome.org/PathwayBrowser/#/R-SSC-2025890 Calcineurin binds NFATC1,2,3 IEA Sus scrofa 29034 R-SSC-2730849 https://reactome.org/PathwayBrowser/#/R-SSC-2730849 Calcineurin binds and dephosphorylates NFAT IEA Sus scrofa 29034 R-SSC-2730867 https://reactome.org/PathwayBrowser/#/R-SSC-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Sus scrofa 29034 R-SSC-2730872 https://reactome.org/PathwayBrowser/#/R-SSC-2730872 Activation of Calcineurin IEA Sus scrofa 29034 R-SSC-428259 https://reactome.org/PathwayBrowser/#/R-SSC-428259 DEGS1 dehydrogenates dihydroceramide IEA Sus scrofa 29034 R-SSC-428260 https://reactome.org/PathwayBrowser/#/R-SSC-428260 DEGS2 oxygenates dihydroceramide IEA Sus scrofa 29034 R-SSC-4551451 https://reactome.org/PathwayBrowser/#/R-SSC-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Sus scrofa 29034 R-SSC-4551465 https://reactome.org/PathwayBrowser/#/R-SSC-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Sus scrofa 29034 R-SSC-5229273 https://reactome.org/PathwayBrowser/#/R-SSC-5229273 LCN2:2,5DHBA binds Fe3+ IEA Sus scrofa 29034 R-SSC-5671707 https://reactome.org/PathwayBrowser/#/R-SSC-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Sus scrofa 29034 R-SSC-5691150 https://reactome.org/PathwayBrowser/#/R-SSC-5691150 TFR2 dimer binds 2xholoTF IEA Sus scrofa 29034 R-SSC-5693761 https://reactome.org/PathwayBrowser/#/R-SSC-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Sus scrofa 29034 R-SSC-6793591 https://reactome.org/PathwayBrowser/#/R-SSC-6793591 LIAS synthesizes lipoyl-GCSH IEA Sus scrofa 29034 R-SSC-8866277 https://reactome.org/PathwayBrowser/#/R-SSC-8866277 AP-2 directly binds some endocytic cargo IEA Sus scrofa 29034 R-SSC-8866405 https://reactome.org/PathwayBrowser/#/R-SSC-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 29034 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa 29034 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa 29034 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa 29034 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 29034 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa 29034 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa 29034 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 29034 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa 29034 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 29034 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa 29034 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa 29034 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 29034 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 29034 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa 29034 R-SSC-917805 https://reactome.org/PathwayBrowser/#/R-SSC-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Sus scrofa 29034 R-SSC-917807 https://reactome.org/PathwayBrowser/#/R-SSC-917807 holoTF:TFRC dimer translocates from plasma membrane to endosome membrane IEA Sus scrofa 29034 R-SSC-917811 https://reactome.org/PathwayBrowser/#/R-SSC-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Sus scrofa 29034 R-SSC-917835 https://reactome.org/PathwayBrowser/#/R-SSC-917835 Fe3+ dissociates from holoTF:TFRC dimer IEA Sus scrofa 29034 R-SSC-917888 https://reactome.org/PathwayBrowser/#/R-SSC-917888 apoTF binds 2Fe3+ to form holoTF IEA Sus scrofa 29034 R-SSC-917891 https://reactome.org/PathwayBrowser/#/R-SSC-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Sus scrofa 29034 R-SSC-917933 https://reactome.org/PathwayBrowser/#/R-SSC-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Sus scrofa 29034 R-SSC-917987 https://reactome.org/PathwayBrowser/#/R-SSC-917987 TFRC dimer binds 2xholoTF IEA Sus scrofa 29034 R-XTR-111742 https://reactome.org/PathwayBrowser/#/R-XTR-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 29034 R-XTR-1222491 https://reactome.org/PathwayBrowser/#/R-XTR-1222491 Lactoferrin scavenges iron ions IEA Xenopus tropicalis 29034 R-XTR-2730867 https://reactome.org/PathwayBrowser/#/R-XTR-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Xenopus tropicalis 29034 R-XTR-428259 https://reactome.org/PathwayBrowser/#/R-XTR-428259 DEGS1 dehydrogenates dihydroceramide IEA Xenopus tropicalis 29034 R-XTR-428260 https://reactome.org/PathwayBrowser/#/R-XTR-428260 DEGS2 oxygenates dihydroceramide IEA Xenopus tropicalis 29034 R-XTR-5229273 https://reactome.org/PathwayBrowser/#/R-XTR-5229273 LCN2:2,5DHBA binds Fe3+ IEA Xenopus tropicalis 29034 R-XTR-5691150 https://reactome.org/PathwayBrowser/#/R-XTR-5691150 TFR2 dimer binds 2xholoTF IEA Xenopus tropicalis 29034 R-XTR-5693761 https://reactome.org/PathwayBrowser/#/R-XTR-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Xenopus tropicalis 29034 R-XTR-8866405 https://reactome.org/PathwayBrowser/#/R-XTR-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 29034 R-XTR-917805 https://reactome.org/PathwayBrowser/#/R-XTR-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Xenopus tropicalis 29034 R-XTR-917811 https://reactome.org/PathwayBrowser/#/R-XTR-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Xenopus tropicalis 29034 R-XTR-917888 https://reactome.org/PathwayBrowser/#/R-XTR-917888 apoTF binds 2Fe3+ to form holoTF IEA Xenopus tropicalis 29034 R-XTR-917891 https://reactome.org/PathwayBrowser/#/R-XTR-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Xenopus tropicalis 29034 R-XTR-917933 https://reactome.org/PathwayBrowser/#/R-XTR-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Xenopus tropicalis 29035 R-BTA-1247910 https://reactome.org/PathwayBrowser/#/R-BTA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Bos taurus 29035 R-BTA-1482961 https://reactome.org/PathwayBrowser/#/R-BTA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Bos taurus 29035 R-BTA-1482962 https://reactome.org/PathwayBrowser/#/R-BTA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Bos taurus 29035 R-BTA-1482973 https://reactome.org/PathwayBrowser/#/R-BTA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Bos taurus 29035 R-BTA-1482976 https://reactome.org/PathwayBrowser/#/R-BTA-1482976 CDP-DAG is converted to PI by CDIPT IEA Bos taurus 29035 R-BTA-1675939 https://reactome.org/PathwayBrowser/#/R-BTA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Bos taurus 29035 R-BTA-1675961 https://reactome.org/PathwayBrowser/#/R-BTA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Bos taurus 29035 R-BTA-1676024 https://reactome.org/PathwayBrowser/#/R-BTA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Bos taurus 29035 R-BTA-1676109 https://reactome.org/PathwayBrowser/#/R-BTA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Bos taurus 29035 R-BTA-180038 https://reactome.org/PathwayBrowser/#/R-BTA-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function IEA Bos taurus 29035 R-BTA-1855165 https://reactome.org/PathwayBrowser/#/R-BTA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 29035 R-BTA-1855166 https://reactome.org/PathwayBrowser/#/R-BTA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Bos taurus 29035 R-BTA-1855198 https://reactome.org/PathwayBrowser/#/R-BTA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 29035 R-BTA-1889955 https://reactome.org/PathwayBrowser/#/R-BTA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Bos taurus 29035 R-BTA-200423 https://reactome.org/PathwayBrowser/#/R-BTA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Bos taurus 29035 R-BTA-2023971 https://reactome.org/PathwayBrowser/#/R-BTA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 29035 R-BTA-2023973 https://reactome.org/PathwayBrowser/#/R-BTA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 29035 R-BTA-2025723 https://reactome.org/PathwayBrowser/#/R-BTA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Bos taurus 29035 R-BTA-202723 https://reactome.org/PathwayBrowser/#/R-BTA-202723 Integrin alpha5beta1 binds FN1 dimer IEA Bos taurus 29035 R-BTA-2046265 https://reactome.org/PathwayBrowser/#/R-BTA-2046265 B4GALTs transfer Gal to the keratan chain IEA Bos taurus 29035 R-BTA-2046298 https://reactome.org/PathwayBrowser/#/R-BTA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Bos taurus 29035 R-BTA-2327746 https://reactome.org/PathwayBrowser/#/R-BTA-2327746 FN1 aggregation IEA Bos taurus 29035 R-BTA-2993802 https://reactome.org/PathwayBrowser/#/R-BTA-2993802 HLCS biotinylates PC:Mn2+ IEA Bos taurus 29035 R-BTA-2993814 https://reactome.org/PathwayBrowser/#/R-BTA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Bos taurus 29035 R-BTA-3299680 https://reactome.org/PathwayBrowser/#/R-BTA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Bos taurus 29035 R-BTA-3323111 https://reactome.org/PathwayBrowser/#/R-BTA-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Bos taurus 29035 R-BTA-354066 https://reactome.org/PathwayBrowser/#/R-BTA-354066 Translocation of PTK2 to Focal complexes IEA Bos taurus 29035 R-BTA-354073 https://reactome.org/PathwayBrowser/#/R-BTA-354073 Autophosphorylation of PTK2 at Y397 IEA Bos taurus 29035 R-BTA-354087 https://reactome.org/PathwayBrowser/#/R-BTA-354087 Recruitment of GRB2 to p-PTK2 IEA Bos taurus 29035 R-BTA-354124 https://reactome.org/PathwayBrowser/#/R-BTA-354124 Phosphorylation of pPTK2 by SRC IEA Bos taurus 29035 R-BTA-354149 https://reactome.org/PathwayBrowser/#/R-BTA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Bos taurus 29035 R-BTA-354165 https://reactome.org/PathwayBrowser/#/R-BTA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Bos taurus 29035 R-BTA-372693 https://reactome.org/PathwayBrowser/#/R-BTA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Bos taurus 29035 R-BTA-372697 https://reactome.org/PathwayBrowser/#/R-BTA-372697 Crk binding to p130cas IEA Bos taurus 29035 R-BTA-372705 https://reactome.org/PathwayBrowser/#/R-BTA-372705 Recruitment of BCAR1 to PTK2 complex IEA Bos taurus 29035 R-BTA-377640 https://reactome.org/PathwayBrowser/#/R-BTA-377640 Autophosphorylation of SRC IEA Bos taurus 29035 R-BTA-377641 https://reactome.org/PathwayBrowser/#/R-BTA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Bos taurus 29035 R-BTA-377643 https://reactome.org/PathwayBrowser/#/R-BTA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Bos taurus 29035 R-BTA-377644 https://reactome.org/PathwayBrowser/#/R-BTA-377644 Release of CSK from SRC IEA Bos taurus 29035 R-BTA-4167511 https://reactome.org/PathwayBrowser/#/R-BTA-4167511 HLCS biotinylates ACACB IEA Bos taurus 29035 R-BTA-429415 https://reactome.org/PathwayBrowser/#/R-BTA-429415 SYK binds to integrin alphaIIb beta3 IEA Bos taurus 29035 R-BTA-429441 https://reactome.org/PathwayBrowser/#/R-BTA-429441 SYK activation by SRC IEA Bos taurus 29035 R-BTA-435171 https://reactome.org/PathwayBrowser/#/R-BTA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Bos taurus 29035 R-BTA-450984 https://reactome.org/PathwayBrowser/#/R-BTA-450984 IDH2 dimer decarboxylates isocitrate IEA Bos taurus 29035 R-BTA-452036 https://reactome.org/PathwayBrowser/#/R-BTA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Bos taurus 29035 R-BTA-453339 https://reactome.org/PathwayBrowser/#/R-BTA-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Bos taurus 29035 R-BTA-5653886 https://reactome.org/PathwayBrowser/#/R-BTA-5653886 B4GALT1 binds LALBA IEA Bos taurus 29035 R-BTA-5655835 https://reactome.org/PathwayBrowser/#/R-BTA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Bos taurus 29035 R-BTA-5655892 https://reactome.org/PathwayBrowser/#/R-BTA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Bos taurus 29035 R-BTA-5655965 https://reactome.org/PathwayBrowser/#/R-BTA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Bos taurus 29035 R-BTA-5672972 https://reactome.org/PathwayBrowser/#/R-BTA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Bos taurus 29035 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 29035 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 29035 R-BTA-5672980 https://reactome.org/PathwayBrowser/#/R-BTA-5672980 Dissociation of RAS:RAF complex IEA Bos taurus 29035 R-BTA-5692462 https://reactome.org/PathwayBrowser/#/R-BTA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Bos taurus 29035 R-BTA-5693153 https://reactome.org/PathwayBrowser/#/R-BTA-5693153 PPM1K dephosphorylates p-BCKDH IEA Bos taurus 29035 R-BTA-5696049 https://reactome.org/PathwayBrowser/#/R-BTA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 29035 R-BTA-6798528 https://reactome.org/PathwayBrowser/#/R-BTA-6798528 S100A8:S100A9 binds Mn2+ IEA Bos taurus 29035 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 29035 R-BTA-70569 https://reactome.org/PathwayBrowser/#/R-BTA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Bos taurus 29035 R-BTA-70967 https://reactome.org/PathwayBrowser/#/R-BTA-70967 IDH3 complex decarboxylates isocitrate IEA Bos taurus 29035 R-BTA-71552 https://reactome.org/PathwayBrowser/#/R-BTA-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Bos taurus 29035 R-BTA-71590 https://reactome.org/PathwayBrowser/#/R-BTA-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Bos taurus 29035 R-BTA-71593 https://reactome.org/PathwayBrowser/#/R-BTA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Bos taurus 29035 R-BTA-75851 https://reactome.org/PathwayBrowser/#/R-BTA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 29035 R-BTA-880007 https://reactome.org/PathwayBrowser/#/R-BTA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Bos taurus 29035 R-BTA-8876889 https://reactome.org/PathwayBrowser/#/R-BTA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 29035 R-BTA-8959798 https://reactome.org/PathwayBrowser/#/R-BTA-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region IEA Bos taurus 29035 R-BTA-9012036 https://reactome.org/PathwayBrowser/#/R-BTA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Bos taurus 29035 R-BTA-9033959 https://reactome.org/PathwayBrowser/#/R-BTA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Bos taurus 29035 R-BTA-9033961 https://reactome.org/PathwayBrowser/#/R-BTA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Bos taurus 29035 R-BTA-9034042 https://reactome.org/PathwayBrowser/#/R-BTA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Bos taurus 29035 R-BTA-9034053 https://reactome.org/PathwayBrowser/#/R-BTA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Bos taurus 29035 R-BTA-9036727 https://reactome.org/PathwayBrowser/#/R-BTA-9036727 GAA hydrolyzes lysosomal glycogen IEA Bos taurus 29035 R-BTA-9638064 https://reactome.org/PathwayBrowser/#/R-BTA-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Bos taurus 29035 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus 29035 R-BTA-9657603 https://reactome.org/PathwayBrowser/#/R-BTA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Bos taurus 29035 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 29035 R-BTA-9657608 https://reactome.org/PathwayBrowser/#/R-BTA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Bos taurus 29035 R-BTA-9753632 https://reactome.org/PathwayBrowser/#/R-BTA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Bos taurus 29035 R-BTA-975919 https://reactome.org/PathwayBrowser/#/R-BTA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Bos taurus 29035 R-BTA-9851347 https://reactome.org/PathwayBrowser/#/R-BTA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Bos taurus 29035 R-BTA-9854415 https://reactome.org/PathwayBrowser/#/R-BTA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Bos taurus 29035 R-BTA-9854463 https://reactome.org/PathwayBrowser/#/R-BTA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Bos taurus 29035 R-BTA-9861631 https://reactome.org/PathwayBrowser/#/R-BTA-9861631 ME1 tetramerizes IEA Bos taurus 29035 R-BTA-9861660 https://reactome.org/PathwayBrowser/#/R-BTA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Bos taurus 29035 R-CEL-1247910 https://reactome.org/PathwayBrowser/#/R-CEL-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Caenorhabditis elegans 29035 R-CEL-1482961 https://reactome.org/PathwayBrowser/#/R-CEL-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Caenorhabditis elegans 29035 R-CEL-1482962 https://reactome.org/PathwayBrowser/#/R-CEL-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Caenorhabditis elegans 29035 R-CEL-1482973 https://reactome.org/PathwayBrowser/#/R-CEL-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Caenorhabditis elegans 29035 R-CEL-1482976 https://reactome.org/PathwayBrowser/#/R-CEL-1482976 CDP-DAG is converted to PI by CDIPT IEA Caenorhabditis elegans 29035 R-CEL-1675939 https://reactome.org/PathwayBrowser/#/R-CEL-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Caenorhabditis elegans 29035 R-CEL-1675961 https://reactome.org/PathwayBrowser/#/R-CEL-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Caenorhabditis elegans 29035 R-CEL-1676024 https://reactome.org/PathwayBrowser/#/R-CEL-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Caenorhabditis elegans 29035 R-CEL-1855165 https://reactome.org/PathwayBrowser/#/R-CEL-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 29035 R-CEL-1855166 https://reactome.org/PathwayBrowser/#/R-CEL-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Caenorhabditis elegans 29035 R-CEL-1855198 https://reactome.org/PathwayBrowser/#/R-CEL-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 29035 R-CEL-1889955 https://reactome.org/PathwayBrowser/#/R-CEL-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Caenorhabditis elegans 29035 R-CEL-200423 https://reactome.org/PathwayBrowser/#/R-CEL-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Caenorhabditis elegans 29035 R-CEL-2023971 https://reactome.org/PathwayBrowser/#/R-CEL-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 29035 R-CEL-2023973 https://reactome.org/PathwayBrowser/#/R-CEL-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 29035 R-CEL-202723 https://reactome.org/PathwayBrowser/#/R-CEL-202723 Integrin alpha5beta1 binds FN1 dimer IEA Caenorhabditis elegans 29035 R-CEL-2327746 https://reactome.org/PathwayBrowser/#/R-CEL-2327746 FN1 aggregation IEA Caenorhabditis elegans 29035 R-CEL-2993802 https://reactome.org/PathwayBrowser/#/R-CEL-2993802 HLCS biotinylates PC:Mn2+ IEA Caenorhabditis elegans 29035 R-CEL-2993814 https://reactome.org/PathwayBrowser/#/R-CEL-2993814 HLCS biotinylates ACACA:Mn2+ IEA Caenorhabditis elegans 29035 R-CEL-3299680 https://reactome.org/PathwayBrowser/#/R-CEL-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Caenorhabditis elegans 29035 R-CEL-3323111 https://reactome.org/PathwayBrowser/#/R-CEL-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Caenorhabditis elegans 29035 R-CEL-354066 https://reactome.org/PathwayBrowser/#/R-CEL-354066 Translocation of PTK2 to Focal complexes IEA Caenorhabditis elegans 29035 R-CEL-354073 https://reactome.org/PathwayBrowser/#/R-CEL-354073 Autophosphorylation of PTK2 at Y397 IEA Caenorhabditis elegans 29035 R-CEL-354087 https://reactome.org/PathwayBrowser/#/R-CEL-354087 Recruitment of GRB2 to p-PTK2 IEA Caenorhabditis elegans 29035 R-CEL-354124 https://reactome.org/PathwayBrowser/#/R-CEL-354124 Phosphorylation of pPTK2 by SRC IEA Caenorhabditis elegans 29035 R-CEL-354149 https://reactome.org/PathwayBrowser/#/R-CEL-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Caenorhabditis elegans 29035 R-CEL-354165 https://reactome.org/PathwayBrowser/#/R-CEL-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Caenorhabditis elegans 29035 R-CEL-377640 https://reactome.org/PathwayBrowser/#/R-CEL-377640 Autophosphorylation of SRC IEA Caenorhabditis elegans 29035 R-CEL-377641 https://reactome.org/PathwayBrowser/#/R-CEL-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Caenorhabditis elegans 29035 R-CEL-377644 https://reactome.org/PathwayBrowser/#/R-CEL-377644 Release of CSK from SRC IEA Caenorhabditis elegans 29035 R-CEL-4167511 https://reactome.org/PathwayBrowser/#/R-CEL-4167511 HLCS biotinylates ACACB IEA Caenorhabditis elegans 29035 R-CEL-429415 https://reactome.org/PathwayBrowser/#/R-CEL-429415 SYK binds to integrin alphaIIb beta3 IEA Caenorhabditis elegans 29035 R-CEL-429441 https://reactome.org/PathwayBrowser/#/R-CEL-429441 SYK activation by SRC IEA Caenorhabditis elegans 29035 R-CEL-435171 https://reactome.org/PathwayBrowser/#/R-CEL-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Caenorhabditis elegans 29035 R-CEL-450984 https://reactome.org/PathwayBrowser/#/R-CEL-450984 IDH2 dimer decarboxylates isocitrate IEA Caenorhabditis elegans 29035 R-CEL-452036 https://reactome.org/PathwayBrowser/#/R-CEL-452036 arginine + H2O => ornithine + urea [ARG2] IEA Caenorhabditis elegans 29035 R-CEL-5655892 https://reactome.org/PathwayBrowser/#/R-CEL-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Caenorhabditis elegans 29035 R-CEL-5672972 https://reactome.org/PathwayBrowser/#/R-CEL-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Caenorhabditis elegans 29035 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 29035 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 29035 R-CEL-5672980 https://reactome.org/PathwayBrowser/#/R-CEL-5672980 Dissociation of RAS:RAF complex IEA Caenorhabditis elegans 29035 R-CEL-5692462 https://reactome.org/PathwayBrowser/#/R-CEL-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Caenorhabditis elegans 29035 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 29035 R-CEL-70569 https://reactome.org/PathwayBrowser/#/R-CEL-70569 arginine + H2O => ornithine + urea [ARG1] IEA Caenorhabditis elegans 29035 R-CEL-70967 https://reactome.org/PathwayBrowser/#/R-CEL-70967 IDH3 complex decarboxylates isocitrate IEA Caenorhabditis elegans 29035 R-CEL-71552 https://reactome.org/PathwayBrowser/#/R-CEL-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Caenorhabditis elegans 29035 R-CEL-71593 https://reactome.org/PathwayBrowser/#/R-CEL-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Caenorhabditis elegans 29035 R-CEL-75851 https://reactome.org/PathwayBrowser/#/R-CEL-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 29035 R-CEL-880007 https://reactome.org/PathwayBrowser/#/R-CEL-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Caenorhabditis elegans 29035 R-CEL-8876889 https://reactome.org/PathwayBrowser/#/R-CEL-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 29035 R-CEL-8959798 https://reactome.org/PathwayBrowser/#/R-CEL-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region IEA Caenorhabditis elegans 29035 R-CEL-9012036 https://reactome.org/PathwayBrowser/#/R-CEL-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 29035 R-CEL-9638064 https://reactome.org/PathwayBrowser/#/R-CEL-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Caenorhabditis elegans 29035 R-CEL-9657599 https://reactome.org/PathwayBrowser/#/R-CEL-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Caenorhabditis elegans 29035 R-CEL-9657603 https://reactome.org/PathwayBrowser/#/R-CEL-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Caenorhabditis elegans 29035 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 29035 R-CEL-9657608 https://reactome.org/PathwayBrowser/#/R-CEL-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Caenorhabditis elegans 29035 R-CEL-9753632 https://reactome.org/PathwayBrowser/#/R-CEL-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Caenorhabditis elegans 29035 R-CEL-9854415 https://reactome.org/PathwayBrowser/#/R-CEL-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Caenorhabditis elegans 29035 R-CEL-9861631 https://reactome.org/PathwayBrowser/#/R-CEL-9861631 ME1 tetramerizes IEA Caenorhabditis elegans 29035 R-CEL-9861660 https://reactome.org/PathwayBrowser/#/R-CEL-9861660 ME1 tetramer decarboxylates OA to PYR IEA Caenorhabditis elegans 29035 R-CFA-1247910 https://reactome.org/PathwayBrowser/#/R-CFA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Canis familiaris 29035 R-CFA-1482961 https://reactome.org/PathwayBrowser/#/R-CFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Canis familiaris 29035 R-CFA-1482962 https://reactome.org/PathwayBrowser/#/R-CFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Canis familiaris 29035 R-CFA-1482973 https://reactome.org/PathwayBrowser/#/R-CFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Canis familiaris 29035 R-CFA-1482976 https://reactome.org/PathwayBrowser/#/R-CFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Canis familiaris 29035 R-CFA-1675939 https://reactome.org/PathwayBrowser/#/R-CFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Canis familiaris 29035 R-CFA-1675961 https://reactome.org/PathwayBrowser/#/R-CFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Canis familiaris 29035 R-CFA-1676024 https://reactome.org/PathwayBrowser/#/R-CFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Canis familiaris 29035 R-CFA-1676109 https://reactome.org/PathwayBrowser/#/R-CFA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Canis familiaris 29035 R-CFA-180038 https://reactome.org/PathwayBrowser/#/R-CFA-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function IEA Canis familiaris 29035 R-CFA-1855165 https://reactome.org/PathwayBrowser/#/R-CFA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 29035 R-CFA-1855166 https://reactome.org/PathwayBrowser/#/R-CFA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Canis familiaris 29035 R-CFA-1855198 https://reactome.org/PathwayBrowser/#/R-CFA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 29035 R-CFA-1889955 https://reactome.org/PathwayBrowser/#/R-CFA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Canis familiaris 29035 R-CFA-200423 https://reactome.org/PathwayBrowser/#/R-CFA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Canis familiaris 29035 R-CFA-2023971 https://reactome.org/PathwayBrowser/#/R-CFA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 29035 R-CFA-2023973 https://reactome.org/PathwayBrowser/#/R-CFA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 29035 R-CFA-2025723 https://reactome.org/PathwayBrowser/#/R-CFA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Canis familiaris 29035 R-CFA-202723 https://reactome.org/PathwayBrowser/#/R-CFA-202723 Integrin alpha5beta1 binds FN1 dimer IEA Canis familiaris 29035 R-CFA-2046265 https://reactome.org/PathwayBrowser/#/R-CFA-2046265 B4GALTs transfer Gal to the keratan chain IEA Canis familiaris 29035 R-CFA-2046298 https://reactome.org/PathwayBrowser/#/R-CFA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Canis familiaris 29035 R-CFA-2327746 https://reactome.org/PathwayBrowser/#/R-CFA-2327746 FN1 aggregation IEA Canis familiaris 29035 R-CFA-2993802 https://reactome.org/PathwayBrowser/#/R-CFA-2993802 HLCS biotinylates PC:Mn2+ IEA Canis familiaris 29035 R-CFA-2993814 https://reactome.org/PathwayBrowser/#/R-CFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Canis familiaris 29035 R-CFA-3299680 https://reactome.org/PathwayBrowser/#/R-CFA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Canis familiaris 29035 R-CFA-3323111 https://reactome.org/PathwayBrowser/#/R-CFA-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Canis familiaris 29035 R-CFA-354066 https://reactome.org/PathwayBrowser/#/R-CFA-354066 Translocation of PTK2 to Focal complexes IEA Canis familiaris 29035 R-CFA-354073 https://reactome.org/PathwayBrowser/#/R-CFA-354073 Autophosphorylation of PTK2 at Y397 IEA Canis familiaris 29035 R-CFA-354087 https://reactome.org/PathwayBrowser/#/R-CFA-354087 Recruitment of GRB2 to p-PTK2 IEA Canis familiaris 29035 R-CFA-354124 https://reactome.org/PathwayBrowser/#/R-CFA-354124 Phosphorylation of pPTK2 by SRC IEA Canis familiaris 29035 R-CFA-354149 https://reactome.org/PathwayBrowser/#/R-CFA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Canis familiaris 29035 R-CFA-354165 https://reactome.org/PathwayBrowser/#/R-CFA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Canis familiaris 29035 R-CFA-372693 https://reactome.org/PathwayBrowser/#/R-CFA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Canis familiaris 29035 R-CFA-372697 https://reactome.org/PathwayBrowser/#/R-CFA-372697 Crk binding to p130cas IEA Canis familiaris 29035 R-CFA-372705 https://reactome.org/PathwayBrowser/#/R-CFA-372705 Recruitment of BCAR1 to PTK2 complex IEA Canis familiaris 29035 R-CFA-377640 https://reactome.org/PathwayBrowser/#/R-CFA-377640 Autophosphorylation of SRC IEA Canis familiaris 29035 R-CFA-377641 https://reactome.org/PathwayBrowser/#/R-CFA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Canis familiaris 29035 R-CFA-377643 https://reactome.org/PathwayBrowser/#/R-CFA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Canis familiaris 29035 R-CFA-377644 https://reactome.org/PathwayBrowser/#/R-CFA-377644 Release of CSK from SRC IEA Canis familiaris 29035 R-CFA-4167511 https://reactome.org/PathwayBrowser/#/R-CFA-4167511 HLCS biotinylates ACACB IEA Canis familiaris 29035 R-CFA-429415 https://reactome.org/PathwayBrowser/#/R-CFA-429415 SYK binds to integrin alphaIIb beta3 IEA Canis familiaris 29035 R-CFA-429441 https://reactome.org/PathwayBrowser/#/R-CFA-429441 SYK activation by SRC IEA Canis familiaris 29035 R-CFA-435171 https://reactome.org/PathwayBrowser/#/R-CFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Canis familiaris 29035 R-CFA-450984 https://reactome.org/PathwayBrowser/#/R-CFA-450984 IDH2 dimer decarboxylates isocitrate IEA Canis familiaris 29035 R-CFA-452036 https://reactome.org/PathwayBrowser/#/R-CFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Canis familiaris 29035 R-CFA-453339 https://reactome.org/PathwayBrowser/#/R-CFA-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Canis familiaris 29035 R-CFA-5653886 https://reactome.org/PathwayBrowser/#/R-CFA-5653886 B4GALT1 binds LALBA IEA Canis familiaris 29035 R-CFA-5655835 https://reactome.org/PathwayBrowser/#/R-CFA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Canis familiaris 29035 R-CFA-5655892 https://reactome.org/PathwayBrowser/#/R-CFA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Canis familiaris 29035 R-CFA-5655965 https://reactome.org/PathwayBrowser/#/R-CFA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Canis familiaris 29035 R-CFA-5672972 https://reactome.org/PathwayBrowser/#/R-CFA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Canis familiaris 29035 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 29035 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 29035 R-CFA-5672980 https://reactome.org/PathwayBrowser/#/R-CFA-5672980 Dissociation of RAS:RAF complex IEA Canis familiaris 29035 R-CFA-5692462 https://reactome.org/PathwayBrowser/#/R-CFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Canis familiaris 29035 R-CFA-5693153 https://reactome.org/PathwayBrowser/#/R-CFA-5693153 PPM1K dephosphorylates p-BCKDH IEA Canis familiaris 29035 R-CFA-5696049 https://reactome.org/PathwayBrowser/#/R-CFA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 29035 R-CFA-6798528 https://reactome.org/PathwayBrowser/#/R-CFA-6798528 S100A8:S100A9 binds Mn2+ IEA Canis familiaris 29035 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 29035 R-CFA-70569 https://reactome.org/PathwayBrowser/#/R-CFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Canis familiaris 29035 R-CFA-70967 https://reactome.org/PathwayBrowser/#/R-CFA-70967 IDH3 complex decarboxylates isocitrate IEA Canis familiaris 29035 R-CFA-71552 https://reactome.org/PathwayBrowser/#/R-CFA-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Canis familiaris 29035 R-CFA-71590 https://reactome.org/PathwayBrowser/#/R-CFA-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Canis familiaris 29035 R-CFA-71593 https://reactome.org/PathwayBrowser/#/R-CFA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Canis familiaris 29035 R-CFA-75851 https://reactome.org/PathwayBrowser/#/R-CFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 29035 R-CFA-880007 https://reactome.org/PathwayBrowser/#/R-CFA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Canis familiaris 29035 R-CFA-8876889 https://reactome.org/PathwayBrowser/#/R-CFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 29035 R-CFA-8959798 https://reactome.org/PathwayBrowser/#/R-CFA-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region IEA Canis familiaris 29035 R-CFA-9012036 https://reactome.org/PathwayBrowser/#/R-CFA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Canis familiaris 29035 R-CFA-9033959 https://reactome.org/PathwayBrowser/#/R-CFA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Canis familiaris 29035 R-CFA-9033961 https://reactome.org/PathwayBrowser/#/R-CFA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Canis familiaris 29035 R-CFA-9034042 https://reactome.org/PathwayBrowser/#/R-CFA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Canis familiaris 29035 R-CFA-9034053 https://reactome.org/PathwayBrowser/#/R-CFA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Canis familiaris 29035 R-CFA-9036727 https://reactome.org/PathwayBrowser/#/R-CFA-9036727 GAA hydrolyzes lysosomal glycogen IEA Canis familiaris 29035 R-CFA-9638064 https://reactome.org/PathwayBrowser/#/R-CFA-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Canis familiaris 29035 R-CFA-9657599 https://reactome.org/PathwayBrowser/#/R-CFA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Canis familiaris 29035 R-CFA-9657603 https://reactome.org/PathwayBrowser/#/R-CFA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Canis familiaris 29035 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 29035 R-CFA-9657608 https://reactome.org/PathwayBrowser/#/R-CFA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Canis familiaris 29035 R-CFA-9753632 https://reactome.org/PathwayBrowser/#/R-CFA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Canis familiaris 29035 R-CFA-975919 https://reactome.org/PathwayBrowser/#/R-CFA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Canis familiaris 29035 R-CFA-9851347 https://reactome.org/PathwayBrowser/#/R-CFA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Canis familiaris 29035 R-CFA-9854415 https://reactome.org/PathwayBrowser/#/R-CFA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Canis familiaris 29035 R-CFA-9854463 https://reactome.org/PathwayBrowser/#/R-CFA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Canis familiaris 29035 R-CFA-9861631 https://reactome.org/PathwayBrowser/#/R-CFA-9861631 ME1 tetramerizes IEA Canis familiaris 29035 R-CFA-9861660 https://reactome.org/PathwayBrowser/#/R-CFA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Canis familiaris 29035 R-DDI-1247910 https://reactome.org/PathwayBrowser/#/R-DDI-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Dictyostelium discoideum 29035 R-DDI-1482961 https://reactome.org/PathwayBrowser/#/R-DDI-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Dictyostelium discoideum 29035 R-DDI-1482962 https://reactome.org/PathwayBrowser/#/R-DDI-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Dictyostelium discoideum 29035 R-DDI-1482973 https://reactome.org/PathwayBrowser/#/R-DDI-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Dictyostelium discoideum 29035 R-DDI-1482976 https://reactome.org/PathwayBrowser/#/R-DDI-1482976 CDP-DAG is converted to PI by CDIPT IEA Dictyostelium discoideum 29035 R-DDI-1675939 https://reactome.org/PathwayBrowser/#/R-DDI-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Dictyostelium discoideum 29035 R-DDI-1675961 https://reactome.org/PathwayBrowser/#/R-DDI-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Dictyostelium discoideum 29035 R-DDI-1676024 https://reactome.org/PathwayBrowser/#/R-DDI-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Dictyostelium discoideum 29035 R-DDI-1676109 https://reactome.org/PathwayBrowser/#/R-DDI-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Dictyostelium discoideum 29035 R-DDI-1855165 https://reactome.org/PathwayBrowser/#/R-DDI-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 29035 R-DDI-1855166 https://reactome.org/PathwayBrowser/#/R-DDI-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Dictyostelium discoideum 29035 R-DDI-1855198 https://reactome.org/PathwayBrowser/#/R-DDI-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 29035 R-DDI-200423 https://reactome.org/PathwayBrowser/#/R-DDI-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Dictyostelium discoideum 29035 R-DDI-2023971 https://reactome.org/PathwayBrowser/#/R-DDI-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 29035 R-DDI-2023973 https://reactome.org/PathwayBrowser/#/R-DDI-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 29035 R-DDI-2993814 https://reactome.org/PathwayBrowser/#/R-DDI-2993814 HLCS biotinylates ACACA:Mn2+ IEA Dictyostelium discoideum 29035 R-DDI-3299680 https://reactome.org/PathwayBrowser/#/R-DDI-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Dictyostelium discoideum 29035 R-DDI-4167511 https://reactome.org/PathwayBrowser/#/R-DDI-4167511 HLCS biotinylates ACACB IEA Dictyostelium discoideum 29035 R-DDI-435171 https://reactome.org/PathwayBrowser/#/R-DDI-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Dictyostelium discoideum 29035 R-DDI-452036 https://reactome.org/PathwayBrowser/#/R-DDI-452036 arginine + H2O => ornithine + urea [ARG2] IEA Dictyostelium discoideum 29035 R-DDI-453339 https://reactome.org/PathwayBrowser/#/R-DDI-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Dictyostelium discoideum 29035 R-DDI-5655892 https://reactome.org/PathwayBrowser/#/R-DDI-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Dictyostelium discoideum 29035 R-DDI-5692462 https://reactome.org/PathwayBrowser/#/R-DDI-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Dictyostelium discoideum 29035 R-DDI-70569 https://reactome.org/PathwayBrowser/#/R-DDI-70569 arginine + H2O => ornithine + urea [ARG1] IEA Dictyostelium discoideum 29035 R-DDI-70967 https://reactome.org/PathwayBrowser/#/R-DDI-70967 IDH3 complex decarboxylates isocitrate IEA Dictyostelium discoideum 29035 R-DDI-71552 https://reactome.org/PathwayBrowser/#/R-DDI-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Dictyostelium discoideum 29035 R-DDI-71590 https://reactome.org/PathwayBrowser/#/R-DDI-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Dictyostelium discoideum 29035 R-DDI-71593 https://reactome.org/PathwayBrowser/#/R-DDI-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Dictyostelium discoideum 29035 R-DDI-75851 https://reactome.org/PathwayBrowser/#/R-DDI-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 29035 R-DDI-880007 https://reactome.org/PathwayBrowser/#/R-DDI-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Dictyostelium discoideum 29035 R-DDI-8876889 https://reactome.org/PathwayBrowser/#/R-DDI-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 29035 R-DDI-8959798 https://reactome.org/PathwayBrowser/#/R-DDI-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region IEA Dictyostelium discoideum 29035 R-DDI-9036727 https://reactome.org/PathwayBrowser/#/R-DDI-9036727 GAA hydrolyzes lysosomal glycogen IEA Dictyostelium discoideum 29035 R-DDI-9753632 https://reactome.org/PathwayBrowser/#/R-DDI-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Dictyostelium discoideum 29035 R-DME-1247910 https://reactome.org/PathwayBrowser/#/R-DME-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Drosophila melanogaster 29035 R-DME-1482961 https://reactome.org/PathwayBrowser/#/R-DME-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Drosophila melanogaster 29035 R-DME-1482962 https://reactome.org/PathwayBrowser/#/R-DME-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Drosophila melanogaster 29035 R-DME-1482973 https://reactome.org/PathwayBrowser/#/R-DME-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Drosophila melanogaster 29035 R-DME-1482976 https://reactome.org/PathwayBrowser/#/R-DME-1482976 CDP-DAG is converted to PI by CDIPT IEA Drosophila melanogaster 29035 R-DME-1675939 https://reactome.org/PathwayBrowser/#/R-DME-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Drosophila melanogaster 29035 R-DME-1675961 https://reactome.org/PathwayBrowser/#/R-DME-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Drosophila melanogaster 29035 R-DME-1676024 https://reactome.org/PathwayBrowser/#/R-DME-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Drosophila melanogaster 29035 R-DME-1676109 https://reactome.org/PathwayBrowser/#/R-DME-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Drosophila melanogaster 29035 R-DME-1855165 https://reactome.org/PathwayBrowser/#/R-DME-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 29035 R-DME-1855166 https://reactome.org/PathwayBrowser/#/R-DME-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Drosophila melanogaster 29035 R-DME-1855198 https://reactome.org/PathwayBrowser/#/R-DME-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 29035 R-DME-1889955 https://reactome.org/PathwayBrowser/#/R-DME-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Drosophila melanogaster 29035 R-DME-199425 https://reactome.org/PathwayBrowser/#/R-DME-199425 PHLPP dephosphorylates S473 in AKT IEA Drosophila melanogaster 29035 R-DME-200423 https://reactome.org/PathwayBrowser/#/R-DME-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Drosophila melanogaster 29035 R-DME-2023971 https://reactome.org/PathwayBrowser/#/R-DME-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 29035 R-DME-2023973 https://reactome.org/PathwayBrowser/#/R-DME-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 29035 R-DME-2025723 https://reactome.org/PathwayBrowser/#/R-DME-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Drosophila melanogaster 29035 R-DME-2046265 https://reactome.org/PathwayBrowser/#/R-DME-2046265 B4GALTs transfer Gal to the keratan chain IEA Drosophila melanogaster 29035 R-DME-2046298 https://reactome.org/PathwayBrowser/#/R-DME-2046298 B4GALTs transfer Gal to a branch of keratan IEA Drosophila melanogaster 29035 R-DME-2993802 https://reactome.org/PathwayBrowser/#/R-DME-2993802 HLCS biotinylates PC:Mn2+ IEA Drosophila melanogaster 29035 R-DME-2993814 https://reactome.org/PathwayBrowser/#/R-DME-2993814 HLCS biotinylates ACACA:Mn2+ IEA Drosophila melanogaster 29035 R-DME-3299680 https://reactome.org/PathwayBrowser/#/R-DME-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Drosophila melanogaster 29035 R-DME-3323111 https://reactome.org/PathwayBrowser/#/R-DME-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Drosophila melanogaster 29035 R-DME-354149 https://reactome.org/PathwayBrowser/#/R-DME-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Drosophila melanogaster 29035 R-DME-377640 https://reactome.org/PathwayBrowser/#/R-DME-377640 Autophosphorylation of SRC IEA Drosophila melanogaster 29035 R-DME-377641 https://reactome.org/PathwayBrowser/#/R-DME-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Drosophila melanogaster 29035 R-DME-377643 https://reactome.org/PathwayBrowser/#/R-DME-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Drosophila melanogaster 29035 R-DME-377644 https://reactome.org/PathwayBrowser/#/R-DME-377644 Release of CSK from SRC IEA Drosophila melanogaster 29035 R-DME-4167511 https://reactome.org/PathwayBrowser/#/R-DME-4167511 HLCS biotinylates ACACB IEA Drosophila melanogaster 29035 R-DME-429415 https://reactome.org/PathwayBrowser/#/R-DME-429415 SYK binds to integrin alphaIIb beta3 IEA Drosophila melanogaster 29035 R-DME-429441 https://reactome.org/PathwayBrowser/#/R-DME-429441 SYK activation by SRC IEA Drosophila melanogaster 29035 R-DME-435171 https://reactome.org/PathwayBrowser/#/R-DME-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Drosophila melanogaster 29035 R-DME-452036 https://reactome.org/PathwayBrowser/#/R-DME-452036 arginine + H2O => ornithine + urea [ARG2] IEA Drosophila melanogaster 29035 R-DME-5653886 https://reactome.org/PathwayBrowser/#/R-DME-5653886 B4GALT1 binds LALBA IEA Drosophila melanogaster 29035 R-DME-5655892 https://reactome.org/PathwayBrowser/#/R-DME-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Drosophila melanogaster 29035 R-DME-5655965 https://reactome.org/PathwayBrowser/#/R-DME-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Drosophila melanogaster 29035 R-DME-5672972 https://reactome.org/PathwayBrowser/#/R-DME-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Drosophila melanogaster 29035 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 29035 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 29035 R-DME-5672980 https://reactome.org/PathwayBrowser/#/R-DME-5672980 Dissociation of RAS:RAF complex IEA Drosophila melanogaster 29035 R-DME-5692462 https://reactome.org/PathwayBrowser/#/R-DME-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Drosophila melanogaster 29035 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 29035 R-DME-70569 https://reactome.org/PathwayBrowser/#/R-DME-70569 arginine + H2O => ornithine + urea [ARG1] IEA Drosophila melanogaster 29035 R-DME-70967 https://reactome.org/PathwayBrowser/#/R-DME-70967 IDH3 complex decarboxylates isocitrate IEA Drosophila melanogaster 29035 R-DME-71552 https://reactome.org/PathwayBrowser/#/R-DME-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Drosophila melanogaster 29035 R-DME-71593 https://reactome.org/PathwayBrowser/#/R-DME-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Drosophila melanogaster 29035 R-DME-75851 https://reactome.org/PathwayBrowser/#/R-DME-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 29035 R-DME-880007 https://reactome.org/PathwayBrowser/#/R-DME-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Drosophila melanogaster 29035 R-DME-8876889 https://reactome.org/PathwayBrowser/#/R-DME-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 29035 R-DME-8959798 https://reactome.org/PathwayBrowser/#/R-DME-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region IEA Drosophila melanogaster 29035 R-DME-9012036 https://reactome.org/PathwayBrowser/#/R-DME-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 29035 R-DME-9638064 https://reactome.org/PathwayBrowser/#/R-DME-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Drosophila melanogaster 29035 R-DME-9657599 https://reactome.org/PathwayBrowser/#/R-DME-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Drosophila melanogaster 29035 R-DME-9657603 https://reactome.org/PathwayBrowser/#/R-DME-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Drosophila melanogaster 29035 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 29035 R-DME-9657608 https://reactome.org/PathwayBrowser/#/R-DME-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Drosophila melanogaster 29035 R-DME-9753632 https://reactome.org/PathwayBrowser/#/R-DME-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Drosophila melanogaster 29035 R-DME-975919 https://reactome.org/PathwayBrowser/#/R-DME-975919 Addition of galactose by beta 4-galactosyltransferases IEA Drosophila melanogaster 29035 R-DME-9851347 https://reactome.org/PathwayBrowser/#/R-DME-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Drosophila melanogaster 29035 R-DME-9861631 https://reactome.org/PathwayBrowser/#/R-DME-9861631 ME1 tetramerizes IEA Drosophila melanogaster 29035 R-DME-9861660 https://reactome.org/PathwayBrowser/#/R-DME-9861660 ME1 tetramer decarboxylates OA to PYR IEA Drosophila melanogaster 29035 R-DRE-1247910 https://reactome.org/PathwayBrowser/#/R-DRE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Danio rerio 29035 R-DRE-1482961 https://reactome.org/PathwayBrowser/#/R-DRE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Danio rerio 29035 R-DRE-1482962 https://reactome.org/PathwayBrowser/#/R-DRE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Danio rerio 29035 R-DRE-1482973 https://reactome.org/PathwayBrowser/#/R-DRE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Danio rerio 29035 R-DRE-1482976 https://reactome.org/PathwayBrowser/#/R-DRE-1482976 CDP-DAG is converted to PI by CDIPT IEA Danio rerio 29035 R-DRE-1676109 https://reactome.org/PathwayBrowser/#/R-DRE-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Danio rerio 29035 R-DRE-1855165 https://reactome.org/PathwayBrowser/#/R-DRE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 29035 R-DRE-1855166 https://reactome.org/PathwayBrowser/#/R-DRE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Danio rerio 29035 R-DRE-1855198 https://reactome.org/PathwayBrowser/#/R-DRE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 29035 R-DRE-1889955 https://reactome.org/PathwayBrowser/#/R-DRE-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Danio rerio 29035 R-DRE-2023971 https://reactome.org/PathwayBrowser/#/R-DRE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 29035 R-DRE-2023973 https://reactome.org/PathwayBrowser/#/R-DRE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 29035 R-DRE-2025723 https://reactome.org/PathwayBrowser/#/R-DRE-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Danio rerio 29035 R-DRE-2046265 https://reactome.org/PathwayBrowser/#/R-DRE-2046265 B4GALTs transfer Gal to the keratan chain IEA Danio rerio 29035 R-DRE-2046298 https://reactome.org/PathwayBrowser/#/R-DRE-2046298 B4GALTs transfer Gal to a branch of keratan IEA Danio rerio 29035 R-DRE-3299680 https://reactome.org/PathwayBrowser/#/R-DRE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Danio rerio 29035 R-DRE-3323111 https://reactome.org/PathwayBrowser/#/R-DRE-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Danio rerio 29035 R-DRE-354149 https://reactome.org/PathwayBrowser/#/R-DRE-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Danio rerio 29035 R-DRE-377640 https://reactome.org/PathwayBrowser/#/R-DRE-377640 Autophosphorylation of SRC IEA Danio rerio 29035 R-DRE-377641 https://reactome.org/PathwayBrowser/#/R-DRE-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Danio rerio 29035 R-DRE-377644 https://reactome.org/PathwayBrowser/#/R-DRE-377644 Release of CSK from SRC IEA Danio rerio 29035 R-DRE-435171 https://reactome.org/PathwayBrowser/#/R-DRE-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Danio rerio 29035 R-DRE-450984 https://reactome.org/PathwayBrowser/#/R-DRE-450984 IDH2 dimer decarboxylates isocitrate IEA Danio rerio 29035 R-DRE-452036 https://reactome.org/PathwayBrowser/#/R-DRE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Danio rerio 29035 R-DRE-5653886 https://reactome.org/PathwayBrowser/#/R-DRE-5653886 B4GALT1 binds LALBA IEA Danio rerio 29035 R-DRE-5696049 https://reactome.org/PathwayBrowser/#/R-DRE-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 29035 R-DRE-6798528 https://reactome.org/PathwayBrowser/#/R-DRE-6798528 S100A8:S100A9 binds Mn2+ IEA Danio rerio 29035 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 29035 R-DRE-880007 https://reactome.org/PathwayBrowser/#/R-DRE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Danio rerio 29035 R-DRE-8959798 https://reactome.org/PathwayBrowser/#/R-DRE-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region IEA Danio rerio 29035 R-DRE-9012036 https://reactome.org/PathwayBrowser/#/R-DRE-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Danio rerio 29035 R-DRE-9033959 https://reactome.org/PathwayBrowser/#/R-DRE-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Danio rerio 29035 R-DRE-9033961 https://reactome.org/PathwayBrowser/#/R-DRE-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Danio rerio 29035 R-DRE-9034042 https://reactome.org/PathwayBrowser/#/R-DRE-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Danio rerio 29035 R-DRE-9034053 https://reactome.org/PathwayBrowser/#/R-DRE-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Danio rerio 29035 R-DRE-9753632 https://reactome.org/PathwayBrowser/#/R-DRE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Danio rerio 29035 R-DRE-975919 https://reactome.org/PathwayBrowser/#/R-DRE-975919 Addition of galactose by beta 4-galactosyltransferases IEA Danio rerio 29035 R-DRE-9851347 https://reactome.org/PathwayBrowser/#/R-DRE-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Danio rerio 29035 R-DRE-9854415 https://reactome.org/PathwayBrowser/#/R-DRE-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Danio rerio 29035 R-DRE-9861631 https://reactome.org/PathwayBrowser/#/R-DRE-9861631 ME1 tetramerizes IEA Danio rerio 29035 R-DRE-9861660 https://reactome.org/PathwayBrowser/#/R-DRE-9861660 ME1 tetramer decarboxylates OA to PYR IEA Danio rerio 29035 R-GGA-1247910 https://reactome.org/PathwayBrowser/#/R-GGA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Gallus gallus 29035 R-GGA-1482961 https://reactome.org/PathwayBrowser/#/R-GGA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Gallus gallus 29035 R-GGA-1482962 https://reactome.org/PathwayBrowser/#/R-GGA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Gallus gallus 29035 R-GGA-1482973 https://reactome.org/PathwayBrowser/#/R-GGA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Gallus gallus 29035 R-GGA-1675939 https://reactome.org/PathwayBrowser/#/R-GGA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Gallus gallus 29035 R-GGA-1675961 https://reactome.org/PathwayBrowser/#/R-GGA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Gallus gallus 29035 R-GGA-1676024 https://reactome.org/PathwayBrowser/#/R-GGA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Gallus gallus 29035 R-GGA-1676109 https://reactome.org/PathwayBrowser/#/R-GGA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Gallus gallus 29035 R-GGA-1855165 https://reactome.org/PathwayBrowser/#/R-GGA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 29035 R-GGA-1855166 https://reactome.org/PathwayBrowser/#/R-GGA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Gallus gallus 29035 R-GGA-1855198 https://reactome.org/PathwayBrowser/#/R-GGA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 29035 R-GGA-1889955 https://reactome.org/PathwayBrowser/#/R-GGA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Gallus gallus 29035 R-GGA-199425 https://reactome.org/PathwayBrowser/#/R-GGA-199425 PHLPP dephosphorylates S473 in AKT IEA Gallus gallus 29035 R-GGA-2023971 https://reactome.org/PathwayBrowser/#/R-GGA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 29035 R-GGA-2023973 https://reactome.org/PathwayBrowser/#/R-GGA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 29035 R-GGA-2025723 https://reactome.org/PathwayBrowser/#/R-GGA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Gallus gallus 29035 R-GGA-2046265 https://reactome.org/PathwayBrowser/#/R-GGA-2046265 B4GALTs transfer Gal to the keratan chain IEA Gallus gallus 29035 R-GGA-2046298 https://reactome.org/PathwayBrowser/#/R-GGA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Gallus gallus 29035 R-GGA-2993814 https://reactome.org/PathwayBrowser/#/R-GGA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Gallus gallus 29035 R-GGA-3299680 https://reactome.org/PathwayBrowser/#/R-GGA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Gallus gallus 29035 R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 29035 R-GGA-354066 https://reactome.org/PathwayBrowser/#/R-GGA-354066 Translocation of PTK2 to Focal complexes IEA Gallus gallus 29035 R-GGA-354073 https://reactome.org/PathwayBrowser/#/R-GGA-354073 Autophosphorylation of PTK2 at Y397 IEA Gallus gallus 29035 R-GGA-354087 https://reactome.org/PathwayBrowser/#/R-GGA-354087 Recruitment of GRB2 to p-PTK2 IEA Gallus gallus 29035 R-GGA-354124 https://reactome.org/PathwayBrowser/#/R-GGA-354124 Phosphorylation of pPTK2 by SRC IEA Gallus gallus 29035 R-GGA-354149 https://reactome.org/PathwayBrowser/#/R-GGA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Gallus gallus 29035 R-GGA-354165 https://reactome.org/PathwayBrowser/#/R-GGA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Gallus gallus 29035 R-GGA-372693 https://reactome.org/PathwayBrowser/#/R-GGA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Gallus gallus 29035 R-GGA-372697 https://reactome.org/PathwayBrowser/#/R-GGA-372697 Crk binding to p130cas IEA Gallus gallus 29035 R-GGA-372705 https://reactome.org/PathwayBrowser/#/R-GGA-372705 Recruitment of BCAR1 to PTK2 complex IEA Gallus gallus 29035 R-GGA-377640 https://reactome.org/PathwayBrowser/#/R-GGA-377640 Autophosphorylation of SRC IEA Gallus gallus 29035 R-GGA-377641 https://reactome.org/PathwayBrowser/#/R-GGA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Gallus gallus 29035 R-GGA-377643 https://reactome.org/PathwayBrowser/#/R-GGA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Gallus gallus 29035 R-GGA-377644 https://reactome.org/PathwayBrowser/#/R-GGA-377644 Release of CSK from SRC IEA Gallus gallus 29035 R-GGA-429415 https://reactome.org/PathwayBrowser/#/R-GGA-429415 SYK binds to integrin alphaIIb beta3 IEA Gallus gallus 29035 R-GGA-429441 https://reactome.org/PathwayBrowser/#/R-GGA-429441 SYK activation by SRC IEA Gallus gallus 29035 R-GGA-435171 https://reactome.org/PathwayBrowser/#/R-GGA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Gallus gallus 29035 R-GGA-450984 https://reactome.org/PathwayBrowser/#/R-GGA-450984 IDH2 dimer decarboxylates isocitrate IEA Gallus gallus 29035 R-GGA-452036 https://reactome.org/PathwayBrowser/#/R-GGA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Gallus gallus 29035 R-GGA-5653886 https://reactome.org/PathwayBrowser/#/R-GGA-5653886 B4GALT1 binds LALBA IEA Gallus gallus 29035 R-GGA-5655835 https://reactome.org/PathwayBrowser/#/R-GGA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Gallus gallus 29035 R-GGA-5655892 https://reactome.org/PathwayBrowser/#/R-GGA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Gallus gallus 29035 R-GGA-5655965 https://reactome.org/PathwayBrowser/#/R-GGA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Gallus gallus 29035 R-GGA-5672972 https://reactome.org/PathwayBrowser/#/R-GGA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Gallus gallus 29035 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 29035 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 29035 R-GGA-5672980 https://reactome.org/PathwayBrowser/#/R-GGA-5672980 Dissociation of RAS:RAF complex IEA Gallus gallus 29035 R-GGA-5692462 https://reactome.org/PathwayBrowser/#/R-GGA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Gallus gallus 29035 R-GGA-5693153 https://reactome.org/PathwayBrowser/#/R-GGA-5693153 PPM1K dephosphorylates p-BCKDH IEA Gallus gallus 29035 R-GGA-5696049 https://reactome.org/PathwayBrowser/#/R-GGA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 29035 R-GGA-6798528 https://reactome.org/PathwayBrowser/#/R-GGA-6798528 S100A8:S100A9 binds Mn2+ IEA Gallus gallus 29035 R-GGA-71552 https://reactome.org/PathwayBrowser/#/R-GGA-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Gallus gallus 29035 R-GGA-71593 https://reactome.org/PathwayBrowser/#/R-GGA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Gallus gallus 29035 R-GGA-75851 https://reactome.org/PathwayBrowser/#/R-GGA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Gallus gallus 29035 R-GGA-880007 https://reactome.org/PathwayBrowser/#/R-GGA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus 29035 R-GGA-9012036 https://reactome.org/PathwayBrowser/#/R-GGA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Gallus gallus 29035 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus 29035 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus 29035 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 29035 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus 29035 R-GGA-9753632 https://reactome.org/PathwayBrowser/#/R-GGA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Gallus gallus 29035 R-GGA-975919 https://reactome.org/PathwayBrowser/#/R-GGA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Gallus gallus 29035 R-GGA-9851347 https://reactome.org/PathwayBrowser/#/R-GGA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Gallus gallus 29035 R-GGA-9854415 https://reactome.org/PathwayBrowser/#/R-GGA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Gallus gallus 29035 R-GGA-9854463 https://reactome.org/PathwayBrowser/#/R-GGA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Gallus gallus 29035 R-GGA-9861631 https://reactome.org/PathwayBrowser/#/R-GGA-9861631 ME1 tetramerizes IEA Gallus gallus 29035 R-GGA-9861660 https://reactome.org/PathwayBrowser/#/R-GGA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Gallus gallus 29035 R-HSA-1247910 https://reactome.org/PathwayBrowser/#/R-HSA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly TAS Homo sapiens 29035 R-HSA-1482961 https://reactome.org/PathwayBrowser/#/R-HSA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane TAS Homo sapiens 29035 R-HSA-1482962 https://reactome.org/PathwayBrowser/#/R-HSA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 TAS Homo sapiens 29035 R-HSA-1482973 https://reactome.org/PathwayBrowser/#/R-HSA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane TAS Homo sapiens 29035 R-HSA-1482976 https://reactome.org/PathwayBrowser/#/R-HSA-1482976 CDP-DAG is converted to PI by CDIPT TAS Homo sapiens 29035 R-HSA-1675939 https://reactome.org/PathwayBrowser/#/R-HSA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane TAS Homo sapiens 29035 R-HSA-1675961 https://reactome.org/PathwayBrowser/#/R-HSA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane TAS Homo sapiens 29035 R-HSA-1676024 https://reactome.org/PathwayBrowser/#/R-HSA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane TAS Homo sapiens 29035 R-HSA-1676109 https://reactome.org/PathwayBrowser/#/R-HSA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane TAS Homo sapiens 29035 R-HSA-180038 https://reactome.org/PathwayBrowser/#/R-HSA-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function TAS Homo sapiens 29035 R-HSA-1855165 https://reactome.org/PathwayBrowser/#/R-HSA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 29035 R-HSA-1855166 https://reactome.org/PathwayBrowser/#/R-HSA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol TAS Homo sapiens 29035 R-HSA-1855198 https://reactome.org/PathwayBrowser/#/R-HSA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 29035 R-HSA-1889955 https://reactome.org/PathwayBrowser/#/R-HSA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker TAS Homo sapiens 29035 R-HSA-199425 https://reactome.org/PathwayBrowser/#/R-HSA-199425 PHLPP dephosphorylates S473 in AKT TAS Homo sapiens 29035 R-HSA-200423 https://reactome.org/PathwayBrowser/#/R-HSA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis TAS Homo sapiens 29035 R-HSA-2023971 https://reactome.org/PathwayBrowser/#/R-HSA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 29035 R-HSA-2023973 https://reactome.org/PathwayBrowser/#/R-HSA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 29035 R-HSA-2025723 https://reactome.org/PathwayBrowser/#/R-HSA-2025723 B4GALTs transfer Gal to the N-glycan precursor TAS Homo sapiens 29035 R-HSA-202723 https://reactome.org/PathwayBrowser/#/R-HSA-202723 Integrin alpha5beta1 binds FN1 dimer TAS Homo sapiens 29035 R-HSA-2046265 https://reactome.org/PathwayBrowser/#/R-HSA-2046265 B4GALTs transfer Gal to the keratan chain TAS Homo sapiens 29035 R-HSA-2046298 https://reactome.org/PathwayBrowser/#/R-HSA-2046298 B4GALTs transfer Gal to a branch of keratan TAS Homo sapiens 29035 R-HSA-2327746 https://reactome.org/PathwayBrowser/#/R-HSA-2327746 FN1 aggregation TAS Homo sapiens 29035 R-HSA-2993802 https://reactome.org/PathwayBrowser/#/R-HSA-2993802 HLCS biotinylates PC:Mn2+ TAS Homo sapiens 29035 R-HSA-2993814 https://reactome.org/PathwayBrowser/#/R-HSA-2993814 HLCS biotinylates ACACA:Mn2+ TAS Homo sapiens 29035 R-HSA-3065958 https://reactome.org/PathwayBrowser/#/R-HSA-3065958 An unknown protease degrades ACACA TAS Homo sapiens 29035 R-HSA-3065959 https://reactome.org/PathwayBrowser/#/R-HSA-3065959 An unknown protease degrades hCBXs TAS Homo sapiens 29035 R-HSA-3299680 https://reactome.org/PathwayBrowser/#/R-HSA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) TAS Homo sapiens 29035 R-HSA-3323111 https://reactome.org/PathwayBrowser/#/R-HSA-3323111 Cytoslic carboxylases translocate to mitochondrial matrix TAS Homo sapiens 29035 R-HSA-3323184 https://reactome.org/PathwayBrowser/#/R-HSA-3323184 Defective HLCS does not biotinylate ACACA:Mn2+ TAS Homo sapiens 29035 R-HSA-354066 https://reactome.org/PathwayBrowser/#/R-HSA-354066 Translocation of PTK2 to Focal complexes TAS Homo sapiens 29035 R-HSA-354073 https://reactome.org/PathwayBrowser/#/R-HSA-354073 Autophosphorylation of PTK2 at Y397 TAS Homo sapiens 29035 R-HSA-354087 https://reactome.org/PathwayBrowser/#/R-HSA-354087 Recruitment of GRB2 to p-PTK2 TAS Homo sapiens 29035 R-HSA-354124 https://reactome.org/PathwayBrowser/#/R-HSA-354124 Phosphorylation of pPTK2 by SRC TAS Homo sapiens 29035 R-HSA-354149 https://reactome.org/PathwayBrowser/#/R-HSA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen TAS Homo sapiens 29035 R-HSA-354165 https://reactome.org/PathwayBrowser/#/R-HSA-354165 Interaction of SOS with GRB2 bound to FADK1 TAS Homo sapiens 29035 R-HSA-3560802 https://reactome.org/PathwayBrowser/#/R-HSA-3560802 Defective B3GAT3 does not transfer GlcA to tetrasaccharide linker TAS Homo sapiens 29035 R-HSA-372693 https://reactome.org/PathwayBrowser/#/R-HSA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex TAS Homo sapiens 29035 R-HSA-372697 https://reactome.org/PathwayBrowser/#/R-HSA-372697 Crk binding to p130cas TAS Homo sapiens 29035 R-HSA-372705 https://reactome.org/PathwayBrowser/#/R-HSA-372705 Recruitment of BCAR1 to PTK2 complex TAS Homo sapiens 29035 R-HSA-377640 https://reactome.org/PathwayBrowser/#/R-HSA-377640 Autophosphorylation of SRC TAS Homo sapiens 29035 R-HSA-377641 https://reactome.org/PathwayBrowser/#/R-HSA-377641 Clustering of Integrin alphaIIb beta3 complexes TAS Homo sapiens 29035 R-HSA-377643 https://reactome.org/PathwayBrowser/#/R-HSA-377643 Dephosphorylation of inactive SRC by PTPB1 TAS Homo sapiens 29035 R-HSA-377644 https://reactome.org/PathwayBrowser/#/R-HSA-377644 Release of CSK from SRC TAS Homo sapiens 29035 R-HSA-4167501 https://reactome.org/PathwayBrowser/#/R-HSA-4167501 An unknown protease degrades ACACB TAS Homo sapiens 29035 R-HSA-4167511 https://reactome.org/PathwayBrowser/#/R-HSA-4167511 HLCS biotinylates ACACB TAS Homo sapiens 29035 R-HSA-429415 https://reactome.org/PathwayBrowser/#/R-HSA-429415 SYK binds to integrin alphaIIb beta3 TAS Homo sapiens 29035 R-HSA-429441 https://reactome.org/PathwayBrowser/#/R-HSA-429441 SYK activation by SRC TAS Homo sapiens 29035 R-HSA-435171 https://reactome.org/PathwayBrowser/#/R-HSA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages TAS Homo sapiens 29035 R-HSA-450984 https://reactome.org/PathwayBrowser/#/R-HSA-450984 IDH2 dimer decarboxylates isocitrate TAS Homo sapiens 29035 R-HSA-452036 https://reactome.org/PathwayBrowser/#/R-HSA-452036 arginine + H2O => ornithine + urea [ARG2] TAS Homo sapiens 29035 R-HSA-453339 https://reactome.org/PathwayBrowser/#/R-HSA-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] TAS Homo sapiens 29035 R-HSA-453358 https://reactome.org/PathwayBrowser/#/R-HSA-453358 poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] IEA Homo sapiens 29035 R-HSA-5653886 https://reactome.org/PathwayBrowser/#/R-HSA-5653886 B4GALT1 binds LALBA TAS Homo sapiens 29035 R-HSA-5655835 https://reactome.org/PathwayBrowser/#/R-HSA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template TAS Homo sapiens 29035 R-HSA-5655892 https://reactome.org/PathwayBrowser/#/R-HSA-5655892 POLK incorporates dNMP opposite to damaged DNA base TAS Homo sapiens 29035 R-HSA-5655965 https://reactome.org/PathwayBrowser/#/R-HSA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini TAS Homo sapiens 29035 R-HSA-5672972 https://reactome.org/PathwayBrowser/#/R-HSA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex TAS Homo sapiens 29035 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 29035 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 29035 R-HSA-5672980 https://reactome.org/PathwayBrowser/#/R-HSA-5672980 Dissociation of RAS:RAF complex TAS Homo sapiens 29035 R-HSA-5692462 https://reactome.org/PathwayBrowser/#/R-HSA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen TAS Homo sapiens 29035 R-HSA-5693153 https://reactome.org/PathwayBrowser/#/R-HSA-5693153 PPM1K dephosphorylates p-BCKDH TAS Homo sapiens 29035 R-HSA-5696049 https://reactome.org/PathwayBrowser/#/R-HSA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 29035 R-HSA-6798528 https://reactome.org/PathwayBrowser/#/R-HSA-6798528 S100A8:S100A9 binds Mn2+ TAS Homo sapiens 29035 R-HSA-6802910 https://reactome.org/PathwayBrowser/#/R-HSA-6802910 Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants TAS Homo sapiens 29035 R-HSA-6802911 https://reactome.org/PathwayBrowser/#/R-HSA-6802911 High kinase activity BRAF complexes phosphorylate MAP2Ks TAS Homo sapiens 29035 R-HSA-6802912 https://reactome.org/PathwayBrowser/#/R-HSA-6802912 High kinase activity BRAF mutants bind MAP2Ks and MAPKs TAS Homo sapiens 29035 R-HSA-6802914 https://reactome.org/PathwayBrowser/#/R-HSA-6802914 RAS:GTP:moderate kinase activity p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 29035 R-HSA-6802918 https://reactome.org/PathwayBrowser/#/R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants TAS Homo sapiens 29035 R-HSA-6802919 https://reactome.org/PathwayBrowser/#/R-HSA-6802919 RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 29035 R-HSA-6802921 https://reactome.org/PathwayBrowser/#/R-HSA-6802921 Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 29035 R-HSA-6802922 https://reactome.org/PathwayBrowser/#/R-HSA-6802922 Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS TAS Homo sapiens 29035 R-HSA-6802925 https://reactome.org/PathwayBrowser/#/R-HSA-6802925 Mutant RAS:p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 29035 R-HSA-6802926 https://reactome.org/PathwayBrowser/#/R-HSA-6802926 Mutant RAS:p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 29035 R-HSA-6802932 https://reactome.org/PathwayBrowser/#/R-HSA-6802932 Dissociation of BRAF/RAF fusion complex TAS Homo sapiens 29035 R-HSA-6802933 https://reactome.org/PathwayBrowser/#/R-HSA-6802933 p-BRAF and RAF fusion dimers phosphorylate MAP2Ks TAS Homo sapiens 29035 R-HSA-6802934 https://reactome.org/PathwayBrowser/#/R-HSA-6802934 p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs TAS Homo sapiens 29035 R-HSA-6802935 https://reactome.org/PathwayBrowser/#/R-HSA-6802935 MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers TAS Homo sapiens 29035 R-HSA-6802942 https://reactome.org/PathwayBrowser/#/R-HSA-6802942 RAS:GTP:p-RAF complexes paradoxically bind MAP2Ks and MAPKs TAS Homo sapiens 29035 R-HSA-6802943 https://reactome.org/PathwayBrowser/#/R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 29035 R-HSA-6803227 https://reactome.org/PathwayBrowser/#/R-HSA-6803227 Dissociation of high activity BRAF complexes TAS Homo sapiens 29035 R-HSA-6803230 https://reactome.org/PathwayBrowser/#/R-HSA-6803230 Dissociation of moderate activity BRAF complexes TAS Homo sapiens 29035 R-HSA-6803233 https://reactome.org/PathwayBrowser/#/R-HSA-6803233 Dissociation of oncogenic RAS:RAF complex TAS Homo sapiens 29035 R-HSA-6803234 https://reactome.org/PathwayBrowser/#/R-HSA-6803234 Dissociation of paradoxically activated RAS:BRAF complexes TAS Homo sapiens 29035 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 29035 R-HSA-70569 https://reactome.org/PathwayBrowser/#/R-HSA-70569 arginine + H2O => ornithine + urea [ARG1] TAS Homo sapiens 29035 R-HSA-70967 https://reactome.org/PathwayBrowser/#/R-HSA-70967 IDH3 complex decarboxylates isocitrate TAS Homo sapiens 29035 R-HSA-71515 https://reactome.org/PathwayBrowser/#/R-HSA-71515 glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] IEA Homo sapiens 29035 R-HSA-71552 https://reactome.org/PathwayBrowser/#/R-HSA-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin TAS Homo sapiens 29035 R-HSA-71590 https://reactome.org/PathwayBrowser/#/R-HSA-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] TAS Homo sapiens 29035 R-HSA-71593 https://reactome.org/PathwayBrowser/#/R-HSA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose TAS Homo sapiens 29035 R-HSA-75851 https://reactome.org/PathwayBrowser/#/R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 29035 R-HSA-880007 https://reactome.org/PathwayBrowser/#/R-HSA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 TAS Homo sapiens 29035 R-HSA-8876889 https://reactome.org/PathwayBrowser/#/R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 29035 R-HSA-8959798 https://reactome.org/PathwayBrowser/#/R-HSA-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region TAS Homo sapiens 29035 R-HSA-9012036 https://reactome.org/PathwayBrowser/#/R-HSA-9012036 ME1 tetramer decarboxylates MAL to PYR TAS Homo sapiens 29035 R-HSA-9033959 https://reactome.org/PathwayBrowser/#/R-HSA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC TAS Homo sapiens 29035 R-HSA-9033961 https://reactome.org/PathwayBrowser/#/R-HSA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC TAS Homo sapiens 29035 R-HSA-9034042 https://reactome.org/PathwayBrowser/#/R-HSA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec TAS Homo sapiens 29035 R-HSA-9034053 https://reactome.org/PathwayBrowser/#/R-HSA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen TAS Homo sapiens 29035 R-HSA-9035988 https://reactome.org/PathwayBrowser/#/R-HSA-9035988 Defective HLCS does not biotinylate PC:Mn2+ TAS Homo sapiens 29035 R-HSA-9036727 https://reactome.org/PathwayBrowser/#/R-HSA-9036727 GAA hydrolyzes lysosomal glycogen TAS Homo sapiens 29035 R-HSA-9036729 https://reactome.org/PathwayBrowser/#/R-HSA-9036729 Defective GAA does not hydrolyze lysosomal glycogen TAS Homo sapiens 29035 R-HSA-9638064 https://reactome.org/PathwayBrowser/#/R-HSA-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker TAS Homo sapiens 29035 R-HSA-9656209 https://reactome.org/PathwayBrowser/#/R-HSA-9656209 Dissociation of RAS:RAF1 mutant complex TAS Homo sapiens 29035 R-HSA-9656211 https://reactome.org/PathwayBrowser/#/R-HSA-9656211 MAP2Ks and MAPKs bind to the activated mutant RAF1 complex TAS Homo sapiens 29035 R-HSA-9656214 https://reactome.org/PathwayBrowser/#/R-HSA-9656214 MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants TAS Homo sapiens 29035 R-HSA-9656215 https://reactome.org/PathwayBrowser/#/R-HSA-9656215 RAF1 mutant complexes phosphorylate MAP2K dimer TAS Homo sapiens 29035 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 29035 R-HSA-9657603 https://reactome.org/PathwayBrowser/#/R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs TAS Homo sapiens 29035 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 29035 R-HSA-9657608 https://reactome.org/PathwayBrowser/#/R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK TAS Homo sapiens 29035 R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 29035 R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 29035 R-HSA-9694344 https://reactome.org/PathwayBrowser/#/R-HSA-9694344 Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching IEA Homo sapiens 29035 R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 29035 R-HSA-9694445 https://reactome.org/PathwayBrowser/#/R-HSA-9694445 nsp16 binds nsp10 TAS Homo sapiens 29035 R-HSA-9694454 https://reactome.org/PathwayBrowser/#/R-HSA-9694454 Replication transcription complex binds SARS-CoV-2 genomic RNA TAS Homo sapiens 29035 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 29035 R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 29035 R-HSA-9694495 https://reactome.org/PathwayBrowser/#/R-HSA-9694495 RTC binds SARS-CoV-2 genomic RNA complement (minus strand) IEA Homo sapiens 29035 R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 29035 R-HSA-9694506 https://reactome.org/PathwayBrowser/#/R-HSA-9694506 Synthesis of SARS-CoV-2 plus strand subgenomic mRNAs TAS Homo sapiens 29035 R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 29035 R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 29035 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 29035 R-HSA-9694576 https://reactome.org/PathwayBrowser/#/R-HSA-9694576 nsp3 binds to nsp7-8 and nsp12-16 IEA Homo sapiens 29035 R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 29035 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 29035 R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 29035 R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 29035 R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 29035 R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 29035 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 29035 R-HSA-9753632 https://reactome.org/PathwayBrowser/#/R-HSA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly TAS Homo sapiens 29035 R-HSA-9754745 https://reactome.org/PathwayBrowser/#/R-HSA-9754745 IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 29035 R-HSA-9755252 https://reactome.org/PathwayBrowser/#/R-HSA-9755252 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 29035 R-HSA-9755258 https://reactome.org/PathwayBrowser/#/R-HSA-9755258 DDX58 binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 29035 R-HSA-975919 https://reactome.org/PathwayBrowser/#/R-HSA-975919 Addition of galactose by beta 4-galactosyltransferases TAS Homo sapiens 29035 R-HSA-9759709 https://reactome.org/PathwayBrowser/#/R-HSA-9759709 CNBP binds SARS-CoV-2 G-rich RNA TAS Homo sapiens 29035 R-HSA-9760510 https://reactome.org/PathwayBrowser/#/R-HSA-9760510 LARP1 binds SARS-CoV-2 RNA TAS Homo sapiens 29035 R-HSA-9761854 https://reactome.org/PathwayBrowser/#/R-HSA-9761854 NFE2L2-dependent ME1 gene expression TAS Homo sapiens 29035 R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 29035 R-HSA-9851347 https://reactome.org/PathwayBrowser/#/R-HSA-9851347 B4GALT5/6 transfer Gal to GlcCer TAS Homo sapiens 29035 R-HSA-9854415 https://reactome.org/PathwayBrowser/#/R-HSA-9854415 ACAT1 tetramer acetylates IDH2 dimer TAS Homo sapiens 29035 R-HSA-9854463 https://reactome.org/PathwayBrowser/#/R-HSA-9854463 SIRT3 deacetylates AcK-IDH2 dimer TAS Homo sapiens 29035 R-HSA-9861631 https://reactome.org/PathwayBrowser/#/R-HSA-9861631 ME1 tetramerizes TAS Homo sapiens 29035 R-HSA-9861660 https://reactome.org/PathwayBrowser/#/R-HSA-9861660 ME1 tetramer decarboxylates OA to PYR TAS Homo sapiens 29035 R-MMU-1247910 https://reactome.org/PathwayBrowser/#/R-MMU-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Mus musculus 29035 R-MMU-1482961 https://reactome.org/PathwayBrowser/#/R-MMU-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Mus musculus 29035 R-MMU-1482962 https://reactome.org/PathwayBrowser/#/R-MMU-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Mus musculus 29035 R-MMU-1482973 https://reactome.org/PathwayBrowser/#/R-MMU-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Mus musculus 29035 R-MMU-1482976 https://reactome.org/PathwayBrowser/#/R-MMU-1482976 CDP-DAG is converted to PI by CDIPT IEA Mus musculus 29035 R-MMU-1675939 https://reactome.org/PathwayBrowser/#/R-MMU-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Mus musculus 29035 R-MMU-1675961 https://reactome.org/PathwayBrowser/#/R-MMU-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Mus musculus 29035 R-MMU-1676024 https://reactome.org/PathwayBrowser/#/R-MMU-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Mus musculus 29035 R-MMU-1676109 https://reactome.org/PathwayBrowser/#/R-MMU-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Mus musculus 29035 R-MMU-180038 https://reactome.org/PathwayBrowser/#/R-MMU-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function IEA Mus musculus 29035 R-MMU-1855165 https://reactome.org/PathwayBrowser/#/R-MMU-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 29035 R-MMU-1855166 https://reactome.org/PathwayBrowser/#/R-MMU-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Mus musculus 29035 R-MMU-1855198 https://reactome.org/PathwayBrowser/#/R-MMU-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 29035 R-MMU-1889955 https://reactome.org/PathwayBrowser/#/R-MMU-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Mus musculus 29035 R-MMU-199425 https://reactome.org/PathwayBrowser/#/R-MMU-199425 PHLPP dephosphorylates S473 in AKT IEA Mus musculus 29035 R-MMU-200423 https://reactome.org/PathwayBrowser/#/R-MMU-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Mus musculus 29035 R-MMU-2023971 https://reactome.org/PathwayBrowser/#/R-MMU-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 29035 R-MMU-2023973 https://reactome.org/PathwayBrowser/#/R-MMU-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 29035 R-MMU-2025723 https://reactome.org/PathwayBrowser/#/R-MMU-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Mus musculus 29035 R-MMU-202723 https://reactome.org/PathwayBrowser/#/R-MMU-202723 Integrin alpha5beta1 binds FN1 dimer IEA Mus musculus 29035 R-MMU-2046265 https://reactome.org/PathwayBrowser/#/R-MMU-2046265 B4GALTs transfer Gal to the keratan chain IEA Mus musculus 29035 R-MMU-2046298 https://reactome.org/PathwayBrowser/#/R-MMU-2046298 B4GALTs transfer Gal to a branch of keratan IEA Mus musculus 29035 R-MMU-2327746 https://reactome.org/PathwayBrowser/#/R-MMU-2327746 FN1 aggregation IEA Mus musculus 29035 R-MMU-2993802 https://reactome.org/PathwayBrowser/#/R-MMU-2993802 HLCS biotinylates PC:Mn2+ IEA Mus musculus 29035 R-MMU-2993814 https://reactome.org/PathwayBrowser/#/R-MMU-2993814 HLCS biotinylates ACACA:Mn2+ IEA Mus musculus 29035 R-MMU-3299680 https://reactome.org/PathwayBrowser/#/R-MMU-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Mus musculus 29035 R-MMU-3323111 https://reactome.org/PathwayBrowser/#/R-MMU-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Mus musculus 29035 R-MMU-354066 https://reactome.org/PathwayBrowser/#/R-MMU-354066 Translocation of PTK2 to Focal complexes IEA Mus musculus 29035 R-MMU-354073 https://reactome.org/PathwayBrowser/#/R-MMU-354073 Autophosphorylation of PTK2 at Y397 IEA Mus musculus 29035 R-MMU-354087 https://reactome.org/PathwayBrowser/#/R-MMU-354087 Recruitment of GRB2 to p-PTK2 IEA Mus musculus 29035 R-MMU-354124 https://reactome.org/PathwayBrowser/#/R-MMU-354124 Phosphorylation of pPTK2 by SRC IEA Mus musculus 29035 R-MMU-354149 https://reactome.org/PathwayBrowser/#/R-MMU-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Mus musculus 29035 R-MMU-354165 https://reactome.org/PathwayBrowser/#/R-MMU-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Mus musculus 29035 R-MMU-372693 https://reactome.org/PathwayBrowser/#/R-MMU-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Mus musculus 29035 R-MMU-372697 https://reactome.org/PathwayBrowser/#/R-MMU-372697 Crk binding to p130cas IEA Mus musculus 29035 R-MMU-372705 https://reactome.org/PathwayBrowser/#/R-MMU-372705 Recruitment of BCAR1 to PTK2 complex IEA Mus musculus 29035 R-MMU-377640 https://reactome.org/PathwayBrowser/#/R-MMU-377640 Autophosphorylation of SRC IEA Mus musculus 29035 R-MMU-377641 https://reactome.org/PathwayBrowser/#/R-MMU-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Mus musculus 29035 R-MMU-377643 https://reactome.org/PathwayBrowser/#/R-MMU-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Mus musculus 29035 R-MMU-377644 https://reactome.org/PathwayBrowser/#/R-MMU-377644 Release of CSK from SRC IEA Mus musculus 29035 R-MMU-4167511 https://reactome.org/PathwayBrowser/#/R-MMU-4167511 HLCS biotinylates ACACB IEA Mus musculus 29035 R-MMU-429415 https://reactome.org/PathwayBrowser/#/R-MMU-429415 SYK binds to integrin alphaIIb beta3 IEA Mus musculus 29035 R-MMU-429441 https://reactome.org/PathwayBrowser/#/R-MMU-429441 SYK activation by SRC IEA Mus musculus 29035 R-MMU-435171 https://reactome.org/PathwayBrowser/#/R-MMU-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Mus musculus 29035 R-MMU-450984 https://reactome.org/PathwayBrowser/#/R-MMU-450984 IDH2 dimer decarboxylates isocitrate IEA Mus musculus 29035 R-MMU-452036 https://reactome.org/PathwayBrowser/#/R-MMU-452036 arginine + H2O => ornithine + urea [ARG2] IEA Mus musculus 29035 R-MMU-5653886 https://reactome.org/PathwayBrowser/#/R-MMU-5653886 B4GALT1 binds LALBA IEA Mus musculus 29035 R-MMU-5655835 https://reactome.org/PathwayBrowser/#/R-MMU-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Mus musculus 29035 R-MMU-5655892 https://reactome.org/PathwayBrowser/#/R-MMU-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Mus musculus 29035 R-MMU-5655965 https://reactome.org/PathwayBrowser/#/R-MMU-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Mus musculus 29035 R-MMU-5672972 https://reactome.org/PathwayBrowser/#/R-MMU-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Mus musculus 29035 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 29035 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 29035 R-MMU-5672980 https://reactome.org/PathwayBrowser/#/R-MMU-5672980 Dissociation of RAS:RAF complex IEA Mus musculus 29035 R-MMU-5692462 https://reactome.org/PathwayBrowser/#/R-MMU-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Mus musculus 29035 R-MMU-5693153 https://reactome.org/PathwayBrowser/#/R-MMU-5693153 PPM1K dephosphorylates p-BCKDH IEA Mus musculus 29035 R-MMU-5696049 https://reactome.org/PathwayBrowser/#/R-MMU-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 29035 R-MMU-6798528 https://reactome.org/PathwayBrowser/#/R-MMU-6798528 S100A8:S100A9 binds Mn2+ IEA Mus musculus 29035 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 29035 R-MMU-70569 https://reactome.org/PathwayBrowser/#/R-MMU-70569 arginine + H2O => ornithine + urea [ARG1] IEA Mus musculus 29035 R-MMU-70967 https://reactome.org/PathwayBrowser/#/R-MMU-70967 IDH3 complex decarboxylates isocitrate IEA Mus musculus 29035 R-MMU-71552 https://reactome.org/PathwayBrowser/#/R-MMU-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Mus musculus 29035 R-MMU-71593 https://reactome.org/PathwayBrowser/#/R-MMU-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Mus musculus 29035 R-MMU-75851 https://reactome.org/PathwayBrowser/#/R-MMU-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 29035 R-MMU-880007 https://reactome.org/PathwayBrowser/#/R-MMU-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Mus musculus 29035 R-MMU-8876889 https://reactome.org/PathwayBrowser/#/R-MMU-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 29035 R-MMU-8959798 https://reactome.org/PathwayBrowser/#/R-MMU-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region IEA Mus musculus 29035 R-MMU-9012036 https://reactome.org/PathwayBrowser/#/R-MMU-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Mus musculus 29035 R-MMU-9033959 https://reactome.org/PathwayBrowser/#/R-MMU-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Mus musculus 29035 R-MMU-9033961 https://reactome.org/PathwayBrowser/#/R-MMU-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Mus musculus 29035 R-MMU-9034042 https://reactome.org/PathwayBrowser/#/R-MMU-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Mus musculus 29035 R-MMU-9034053 https://reactome.org/PathwayBrowser/#/R-MMU-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Mus musculus 29035 R-MMU-9036727 https://reactome.org/PathwayBrowser/#/R-MMU-9036727 GAA hydrolyzes lysosomal glycogen IEA Mus musculus 29035 R-MMU-9638064 https://reactome.org/PathwayBrowser/#/R-MMU-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Mus musculus 29035 R-MMU-9657599 https://reactome.org/PathwayBrowser/#/R-MMU-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Mus musculus 29035 R-MMU-9657603 https://reactome.org/PathwayBrowser/#/R-MMU-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Mus musculus 29035 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 29035 R-MMU-9657608 https://reactome.org/PathwayBrowser/#/R-MMU-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Mus musculus 29035 R-MMU-9753632 https://reactome.org/PathwayBrowser/#/R-MMU-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Mus musculus 29035 R-MMU-975919 https://reactome.org/PathwayBrowser/#/R-MMU-975919 Addition of galactose by beta 4-galactosyltransferases IEA Mus musculus 29035 R-MMU-9851347 https://reactome.org/PathwayBrowser/#/R-MMU-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Mus musculus 29035 R-MMU-9854415 https://reactome.org/PathwayBrowser/#/R-MMU-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Mus musculus 29035 R-MMU-9854463 https://reactome.org/PathwayBrowser/#/R-MMU-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Mus musculus 29035 R-MMU-9861631 https://reactome.org/PathwayBrowser/#/R-MMU-9861631 ME1 tetramerizes IEA Mus musculus 29035 R-MMU-9861660 https://reactome.org/PathwayBrowser/#/R-MMU-9861660 ME1 tetramer decarboxylates OA to PYR IEA Mus musculus 29035 R-MTU-964912 https://reactome.org/PathwayBrowser/#/R-MTU-964912 DHAP from Ery4P and PEP TAS Mycobacterium tuberculosis 29035 R-PFA-1482961 https://reactome.org/PathwayBrowser/#/R-PFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Plasmodium falciparum 29035 R-PFA-1482962 https://reactome.org/PathwayBrowser/#/R-PFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Plasmodium falciparum 29035 R-PFA-1482973 https://reactome.org/PathwayBrowser/#/R-PFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Plasmodium falciparum 29035 R-PFA-1482976 https://reactome.org/PathwayBrowser/#/R-PFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Plasmodium falciparum 29035 R-PFA-1675939 https://reactome.org/PathwayBrowser/#/R-PFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Plasmodium falciparum 29035 R-PFA-1675961 https://reactome.org/PathwayBrowser/#/R-PFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Plasmodium falciparum 29035 R-PFA-1676024 https://reactome.org/PathwayBrowser/#/R-PFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Plasmodium falciparum 29035 R-PFA-2993814 https://reactome.org/PathwayBrowser/#/R-PFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Plasmodium falciparum 29035 R-PFA-4167511 https://reactome.org/PathwayBrowser/#/R-PFA-4167511 HLCS biotinylates ACACB IEA Plasmodium falciparum 29035 R-PFA-435171 https://reactome.org/PathwayBrowser/#/R-PFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Plasmodium falciparum 29035 R-PFA-450984 https://reactome.org/PathwayBrowser/#/R-PFA-450984 IDH2 dimer decarboxylates isocitrate IEA Plasmodium falciparum 29035 R-PFA-452036 https://reactome.org/PathwayBrowser/#/R-PFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Plasmodium falciparum 29035 R-PFA-5655892 https://reactome.org/PathwayBrowser/#/R-PFA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Plasmodium falciparum 29035 R-PFA-5655965 https://reactome.org/PathwayBrowser/#/R-PFA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Plasmodium falciparum 29035 R-PFA-5692462 https://reactome.org/PathwayBrowser/#/R-PFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Plasmodium falciparum 29035 R-PFA-70569 https://reactome.org/PathwayBrowser/#/R-PFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Plasmodium falciparum 29035 R-PFA-75851 https://reactome.org/PathwayBrowser/#/R-PFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 29035 R-PFA-8876889 https://reactome.org/PathwayBrowser/#/R-PFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 29035 R-PFA-9854415 https://reactome.org/PathwayBrowser/#/R-PFA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Plasmodium falciparum 29035 R-RNO-1247910 https://reactome.org/PathwayBrowser/#/R-RNO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Rattus norvegicus 29035 R-RNO-1482961 https://reactome.org/PathwayBrowser/#/R-RNO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Rattus norvegicus 29035 R-RNO-1482962 https://reactome.org/PathwayBrowser/#/R-RNO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Rattus norvegicus 29035 R-RNO-1482973 https://reactome.org/PathwayBrowser/#/R-RNO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Rattus norvegicus 29035 R-RNO-1482976 https://reactome.org/PathwayBrowser/#/R-RNO-1482976 CDP-DAG is converted to PI by CDIPT IEA Rattus norvegicus 29035 R-RNO-1675939 https://reactome.org/PathwayBrowser/#/R-RNO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Rattus norvegicus 29035 R-RNO-1675961 https://reactome.org/PathwayBrowser/#/R-RNO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Rattus norvegicus 29035 R-RNO-1676024 https://reactome.org/PathwayBrowser/#/R-RNO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Rattus norvegicus 29035 R-RNO-1676109 https://reactome.org/PathwayBrowser/#/R-RNO-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Rattus norvegicus 29035 R-RNO-180038 https://reactome.org/PathwayBrowser/#/R-RNO-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function IEA Rattus norvegicus 29035 R-RNO-1855165 https://reactome.org/PathwayBrowser/#/R-RNO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 29035 R-RNO-1855166 https://reactome.org/PathwayBrowser/#/R-RNO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Rattus norvegicus 29035 R-RNO-1855198 https://reactome.org/PathwayBrowser/#/R-RNO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 29035 R-RNO-1889955 https://reactome.org/PathwayBrowser/#/R-RNO-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Rattus norvegicus 29035 R-RNO-199425 https://reactome.org/PathwayBrowser/#/R-RNO-199425 PHLPP dephosphorylates S473 in AKT IEA Rattus norvegicus 29035 R-RNO-200423 https://reactome.org/PathwayBrowser/#/R-RNO-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Rattus norvegicus 29035 R-RNO-2023971 https://reactome.org/PathwayBrowser/#/R-RNO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 29035 R-RNO-2023973 https://reactome.org/PathwayBrowser/#/R-RNO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 29035 R-RNO-2025723 https://reactome.org/PathwayBrowser/#/R-RNO-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Rattus norvegicus 29035 R-RNO-202723 https://reactome.org/PathwayBrowser/#/R-RNO-202723 Integrin alpha5beta1 binds FN1 dimer IEA Rattus norvegicus 29035 R-RNO-2046265 https://reactome.org/PathwayBrowser/#/R-RNO-2046265 B4GALTs transfer Gal to the keratan chain IEA Rattus norvegicus 29035 R-RNO-2046298 https://reactome.org/PathwayBrowser/#/R-RNO-2046298 B4GALTs transfer Gal to a branch of keratan IEA Rattus norvegicus 29035 R-RNO-2327746 https://reactome.org/PathwayBrowser/#/R-RNO-2327746 FN1 aggregation IEA Rattus norvegicus 29035 R-RNO-2993802 https://reactome.org/PathwayBrowser/#/R-RNO-2993802 HLCS biotinylates PC:Mn2+ IEA Rattus norvegicus 29035 R-RNO-2993814 https://reactome.org/PathwayBrowser/#/R-RNO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Rattus norvegicus 29035 R-RNO-3299680 https://reactome.org/PathwayBrowser/#/R-RNO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Rattus norvegicus 29035 R-RNO-3323111 https://reactome.org/PathwayBrowser/#/R-RNO-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Rattus norvegicus 29035 R-RNO-354066 https://reactome.org/PathwayBrowser/#/R-RNO-354066 Translocation of PTK2 to Focal complexes IEA Rattus norvegicus 29035 R-RNO-354073 https://reactome.org/PathwayBrowser/#/R-RNO-354073 Autophosphorylation of PTK2 at Y397 IEA Rattus norvegicus 29035 R-RNO-354087 https://reactome.org/PathwayBrowser/#/R-RNO-354087 Recruitment of GRB2 to p-PTK2 IEA Rattus norvegicus 29035 R-RNO-354124 https://reactome.org/PathwayBrowser/#/R-RNO-354124 Phosphorylation of pPTK2 by SRC IEA Rattus norvegicus 29035 R-RNO-354149 https://reactome.org/PathwayBrowser/#/R-RNO-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Rattus norvegicus 29035 R-RNO-354165 https://reactome.org/PathwayBrowser/#/R-RNO-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Rattus norvegicus 29035 R-RNO-372693 https://reactome.org/PathwayBrowser/#/R-RNO-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Rattus norvegicus 29035 R-RNO-372697 https://reactome.org/PathwayBrowser/#/R-RNO-372697 Crk binding to p130cas IEA Rattus norvegicus 29035 R-RNO-372705 https://reactome.org/PathwayBrowser/#/R-RNO-372705 Recruitment of BCAR1 to PTK2 complex IEA Rattus norvegicus 29035 R-RNO-377640 https://reactome.org/PathwayBrowser/#/R-RNO-377640 Autophosphorylation of SRC IEA Rattus norvegicus 29035 R-RNO-377641 https://reactome.org/PathwayBrowser/#/R-RNO-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Rattus norvegicus 29035 R-RNO-377643 https://reactome.org/PathwayBrowser/#/R-RNO-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Rattus norvegicus 29035 R-RNO-377644 https://reactome.org/PathwayBrowser/#/R-RNO-377644 Release of CSK from SRC IEA Rattus norvegicus 29035 R-RNO-4167511 https://reactome.org/PathwayBrowser/#/R-RNO-4167511 HLCS biotinylates ACACB IEA Rattus norvegicus 29035 R-RNO-429415 https://reactome.org/PathwayBrowser/#/R-RNO-429415 SYK binds to integrin alphaIIb beta3 IEA Rattus norvegicus 29035 R-RNO-429441 https://reactome.org/PathwayBrowser/#/R-RNO-429441 SYK activation by SRC IEA Rattus norvegicus 29035 R-RNO-435171 https://reactome.org/PathwayBrowser/#/R-RNO-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Rattus norvegicus 29035 R-RNO-450984 https://reactome.org/PathwayBrowser/#/R-RNO-450984 IDH2 dimer decarboxylates isocitrate IEA Rattus norvegicus 29035 R-RNO-452036 https://reactome.org/PathwayBrowser/#/R-RNO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Rattus norvegicus 29035 R-RNO-5655835 https://reactome.org/PathwayBrowser/#/R-RNO-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Rattus norvegicus 29035 R-RNO-5655892 https://reactome.org/PathwayBrowser/#/R-RNO-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Rattus norvegicus 29035 R-RNO-5655965 https://reactome.org/PathwayBrowser/#/R-RNO-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Rattus norvegicus 29035 R-RNO-5672972 https://reactome.org/PathwayBrowser/#/R-RNO-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Rattus norvegicus 29035 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 29035 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 29035 R-RNO-5672980 https://reactome.org/PathwayBrowser/#/R-RNO-5672980 Dissociation of RAS:RAF complex IEA Rattus norvegicus 29035 R-RNO-5692462 https://reactome.org/PathwayBrowser/#/R-RNO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Rattus norvegicus 29035 R-RNO-5693153 https://reactome.org/PathwayBrowser/#/R-RNO-5693153 PPM1K dephosphorylates p-BCKDH IEA Rattus norvegicus 29035 R-RNO-5696049 https://reactome.org/PathwayBrowser/#/R-RNO-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 29035 R-RNO-6798528 https://reactome.org/PathwayBrowser/#/R-RNO-6798528 S100A8:S100A9 binds Mn2+ IEA Rattus norvegicus 29035 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 29035 R-RNO-70569 https://reactome.org/PathwayBrowser/#/R-RNO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Rattus norvegicus 29035 R-RNO-70967 https://reactome.org/PathwayBrowser/#/R-RNO-70967 IDH3 complex decarboxylates isocitrate IEA Rattus norvegicus 29035 R-RNO-71552 https://reactome.org/PathwayBrowser/#/R-RNO-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Rattus norvegicus 29035 R-RNO-71593 https://reactome.org/PathwayBrowser/#/R-RNO-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Rattus norvegicus 29035 R-RNO-75851 https://reactome.org/PathwayBrowser/#/R-RNO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 29035 R-RNO-880007 https://reactome.org/PathwayBrowser/#/R-RNO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Rattus norvegicus 29035 R-RNO-8876889 https://reactome.org/PathwayBrowser/#/R-RNO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 29035 R-RNO-8959798 https://reactome.org/PathwayBrowser/#/R-RNO-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region IEA Rattus norvegicus 29035 R-RNO-9012036 https://reactome.org/PathwayBrowser/#/R-RNO-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 29035 R-RNO-9033959 https://reactome.org/PathwayBrowser/#/R-RNO-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Rattus norvegicus 29035 R-RNO-9033961 https://reactome.org/PathwayBrowser/#/R-RNO-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Rattus norvegicus 29035 R-RNO-9034042 https://reactome.org/PathwayBrowser/#/R-RNO-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Rattus norvegicus 29035 R-RNO-9034053 https://reactome.org/PathwayBrowser/#/R-RNO-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Rattus norvegicus 29035 R-RNO-9036727 https://reactome.org/PathwayBrowser/#/R-RNO-9036727 GAA hydrolyzes lysosomal glycogen IEA Rattus norvegicus 29035 R-RNO-9657599 https://reactome.org/PathwayBrowser/#/R-RNO-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Rattus norvegicus 29035 R-RNO-9657603 https://reactome.org/PathwayBrowser/#/R-RNO-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Rattus norvegicus 29035 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 29035 R-RNO-9657608 https://reactome.org/PathwayBrowser/#/R-RNO-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Rattus norvegicus 29035 R-RNO-9753632 https://reactome.org/PathwayBrowser/#/R-RNO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Rattus norvegicus 29035 R-RNO-975919 https://reactome.org/PathwayBrowser/#/R-RNO-975919 Addition of galactose by beta 4-galactosyltransferases IEA Rattus norvegicus 29035 R-RNO-9851347 https://reactome.org/PathwayBrowser/#/R-RNO-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Rattus norvegicus 29035 R-RNO-9854415 https://reactome.org/PathwayBrowser/#/R-RNO-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Rattus norvegicus 29035 R-RNO-9854463 https://reactome.org/PathwayBrowser/#/R-RNO-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Rattus norvegicus 29035 R-RNO-9861631 https://reactome.org/PathwayBrowser/#/R-RNO-9861631 ME1 tetramerizes IEA Rattus norvegicus 29035 R-RNO-9861660 https://reactome.org/PathwayBrowser/#/R-RNO-9861660 ME1 tetramer decarboxylates OA to PYR IEA Rattus norvegicus 29035 R-SCE-1247910 https://reactome.org/PathwayBrowser/#/R-SCE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Saccharomyces cerevisiae 29035 R-SCE-1482961 https://reactome.org/PathwayBrowser/#/R-SCE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Saccharomyces cerevisiae 29035 R-SCE-1482962 https://reactome.org/PathwayBrowser/#/R-SCE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Saccharomyces cerevisiae 29035 R-SCE-1482973 https://reactome.org/PathwayBrowser/#/R-SCE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Saccharomyces cerevisiae 29035 R-SCE-1482976 https://reactome.org/PathwayBrowser/#/R-SCE-1482976 CDP-DAG is converted to PI by CDIPT IEA Saccharomyces cerevisiae 29035 R-SCE-1675939 https://reactome.org/PathwayBrowser/#/R-SCE-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Saccharomyces cerevisiae 29035 R-SCE-1675961 https://reactome.org/PathwayBrowser/#/R-SCE-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Saccharomyces cerevisiae 29035 R-SCE-1676024 https://reactome.org/PathwayBrowser/#/R-SCE-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Saccharomyces cerevisiae 29035 R-SCE-1855165 https://reactome.org/PathwayBrowser/#/R-SCE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 29035 R-SCE-1855166 https://reactome.org/PathwayBrowser/#/R-SCE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Saccharomyces cerevisiae 29035 R-SCE-1855198 https://reactome.org/PathwayBrowser/#/R-SCE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 29035 R-SCE-200423 https://reactome.org/PathwayBrowser/#/R-SCE-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Saccharomyces cerevisiae 29035 R-SCE-2023971 https://reactome.org/PathwayBrowser/#/R-SCE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 29035 R-SCE-2023973 https://reactome.org/PathwayBrowser/#/R-SCE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 29035 R-SCE-2993802 https://reactome.org/PathwayBrowser/#/R-SCE-2993802 HLCS biotinylates PC:Mn2+ IEA Saccharomyces cerevisiae 29035 R-SCE-2993814 https://reactome.org/PathwayBrowser/#/R-SCE-2993814 HLCS biotinylates ACACA:Mn2+ IEA Saccharomyces cerevisiae 29035 R-SCE-3299680 https://reactome.org/PathwayBrowser/#/R-SCE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Saccharomyces cerevisiae 29035 R-SCE-3323111 https://reactome.org/PathwayBrowser/#/R-SCE-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Saccharomyces cerevisiae 29035 R-SCE-4167511 https://reactome.org/PathwayBrowser/#/R-SCE-4167511 HLCS biotinylates ACACB IEA Saccharomyces cerevisiae 29035 R-SCE-452036 https://reactome.org/PathwayBrowser/#/R-SCE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Saccharomyces cerevisiae 29035 R-SCE-453339 https://reactome.org/PathwayBrowser/#/R-SCE-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Saccharomyces cerevisiae 29035 R-SCE-5655892 https://reactome.org/PathwayBrowser/#/R-SCE-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Saccharomyces cerevisiae 29035 R-SCE-5655965 https://reactome.org/PathwayBrowser/#/R-SCE-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Saccharomyces cerevisiae 29035 R-SCE-5692462 https://reactome.org/PathwayBrowser/#/R-SCE-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Saccharomyces cerevisiae 29035 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 29035 R-SCE-70569 https://reactome.org/PathwayBrowser/#/R-SCE-70569 arginine + H2O => ornithine + urea [ARG1] IEA Saccharomyces cerevisiae 29035 R-SCE-70967 https://reactome.org/PathwayBrowser/#/R-SCE-70967 IDH3 complex decarboxylates isocitrate IEA Saccharomyces cerevisiae 29035 R-SCE-71552 https://reactome.org/PathwayBrowser/#/R-SCE-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Saccharomyces cerevisiae 29035 R-SCE-71590 https://reactome.org/PathwayBrowser/#/R-SCE-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Saccharomyces cerevisiae 29035 R-SCE-71593 https://reactome.org/PathwayBrowser/#/R-SCE-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Saccharomyces cerevisiae 29035 R-SCE-75851 https://reactome.org/PathwayBrowser/#/R-SCE-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 29035 R-SCE-880007 https://reactome.org/PathwayBrowser/#/R-SCE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Saccharomyces cerevisiae 29035 R-SCE-8876889 https://reactome.org/PathwayBrowser/#/R-SCE-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 29035 R-SCE-8959798 https://reactome.org/PathwayBrowser/#/R-SCE-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region IEA Saccharomyces cerevisiae 29035 R-SCE-9753632 https://reactome.org/PathwayBrowser/#/R-SCE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Saccharomyces cerevisiae 29035 R-SPO-1247910 https://reactome.org/PathwayBrowser/#/R-SPO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Schizosaccharomyces pombe 29035 R-SPO-1482961 https://reactome.org/PathwayBrowser/#/R-SPO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Schizosaccharomyces pombe 29035 R-SPO-1482962 https://reactome.org/PathwayBrowser/#/R-SPO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Schizosaccharomyces pombe 29035 R-SPO-1482973 https://reactome.org/PathwayBrowser/#/R-SPO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Schizosaccharomyces pombe 29035 R-SPO-1482976 https://reactome.org/PathwayBrowser/#/R-SPO-1482976 CDP-DAG is converted to PI by CDIPT IEA Schizosaccharomyces pombe 29035 R-SPO-1675939 https://reactome.org/PathwayBrowser/#/R-SPO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Schizosaccharomyces pombe 29035 R-SPO-1675961 https://reactome.org/PathwayBrowser/#/R-SPO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Schizosaccharomyces pombe 29035 R-SPO-1676024 https://reactome.org/PathwayBrowser/#/R-SPO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Schizosaccharomyces pombe 29035 R-SPO-1855165 https://reactome.org/PathwayBrowser/#/R-SPO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 29035 R-SPO-1855166 https://reactome.org/PathwayBrowser/#/R-SPO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Schizosaccharomyces pombe 29035 R-SPO-1855198 https://reactome.org/PathwayBrowser/#/R-SPO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 29035 R-SPO-200423 https://reactome.org/PathwayBrowser/#/R-SPO-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Schizosaccharomyces pombe 29035 R-SPO-2023971 https://reactome.org/PathwayBrowser/#/R-SPO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 29035 R-SPO-2023973 https://reactome.org/PathwayBrowser/#/R-SPO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 29035 R-SPO-2993802 https://reactome.org/PathwayBrowser/#/R-SPO-2993802 HLCS biotinylates PC:Mn2+ IEA Schizosaccharomyces pombe 29035 R-SPO-2993814 https://reactome.org/PathwayBrowser/#/R-SPO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Schizosaccharomyces pombe 29035 R-SPO-3299680 https://reactome.org/PathwayBrowser/#/R-SPO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Schizosaccharomyces pombe 29035 R-SPO-3323111 https://reactome.org/PathwayBrowser/#/R-SPO-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Schizosaccharomyces pombe 29035 R-SPO-4167511 https://reactome.org/PathwayBrowser/#/R-SPO-4167511 HLCS biotinylates ACACB IEA Schizosaccharomyces pombe 29035 R-SPO-452036 https://reactome.org/PathwayBrowser/#/R-SPO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Schizosaccharomyces pombe 29035 R-SPO-5655835 https://reactome.org/PathwayBrowser/#/R-SPO-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Schizosaccharomyces pombe 29035 R-SPO-5655892 https://reactome.org/PathwayBrowser/#/R-SPO-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Schizosaccharomyces pombe 29035 R-SPO-5655965 https://reactome.org/PathwayBrowser/#/R-SPO-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Schizosaccharomyces pombe 29035 R-SPO-5692462 https://reactome.org/PathwayBrowser/#/R-SPO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Schizosaccharomyces pombe 29035 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 29035 R-SPO-70569 https://reactome.org/PathwayBrowser/#/R-SPO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Schizosaccharomyces pombe 29035 R-SPO-70967 https://reactome.org/PathwayBrowser/#/R-SPO-70967 IDH3 complex decarboxylates isocitrate IEA Schizosaccharomyces pombe 29035 R-SPO-75851 https://reactome.org/PathwayBrowser/#/R-SPO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 29035 R-SPO-880007 https://reactome.org/PathwayBrowser/#/R-SPO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Schizosaccharomyces pombe 29035 R-SPO-8876889 https://reactome.org/PathwayBrowser/#/R-SPO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 29035 R-SPO-8959798 https://reactome.org/PathwayBrowser/#/R-SPO-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region IEA Schizosaccharomyces pombe 29035 R-SPO-9036727 https://reactome.org/PathwayBrowser/#/R-SPO-9036727 GAA hydrolyzes lysosomal glycogen IEA Schizosaccharomyces pombe 29035 R-SPO-9753632 https://reactome.org/PathwayBrowser/#/R-SPO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Schizosaccharomyces pombe 29035 R-SSC-1247910 https://reactome.org/PathwayBrowser/#/R-SSC-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Sus scrofa 29035 R-SSC-1482961 https://reactome.org/PathwayBrowser/#/R-SSC-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Sus scrofa 29035 R-SSC-1482962 https://reactome.org/PathwayBrowser/#/R-SSC-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Sus scrofa 29035 R-SSC-1482973 https://reactome.org/PathwayBrowser/#/R-SSC-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Sus scrofa 29035 R-SSC-1482976 https://reactome.org/PathwayBrowser/#/R-SSC-1482976 CDP-DAG is converted to PI by CDIPT IEA Sus scrofa 29035 R-SSC-1675939 https://reactome.org/PathwayBrowser/#/R-SSC-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Sus scrofa 29035 R-SSC-1675961 https://reactome.org/PathwayBrowser/#/R-SSC-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Sus scrofa 29035 R-SSC-1676024 https://reactome.org/PathwayBrowser/#/R-SSC-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Sus scrofa 29035 R-SSC-1676109 https://reactome.org/PathwayBrowser/#/R-SSC-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Sus scrofa 29035 R-SSC-180038 https://reactome.org/PathwayBrowser/#/R-SSC-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function IEA Sus scrofa 29035 R-SSC-1855165 https://reactome.org/PathwayBrowser/#/R-SSC-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 29035 R-SSC-1855166 https://reactome.org/PathwayBrowser/#/R-SSC-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Sus scrofa 29035 R-SSC-1855198 https://reactome.org/PathwayBrowser/#/R-SSC-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 29035 R-SSC-1889955 https://reactome.org/PathwayBrowser/#/R-SSC-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Sus scrofa 29035 R-SSC-200423 https://reactome.org/PathwayBrowser/#/R-SSC-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Sus scrofa 29035 R-SSC-2023971 https://reactome.org/PathwayBrowser/#/R-SSC-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 29035 R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 29035 R-SSC-2025723 https://reactome.org/PathwayBrowser/#/R-SSC-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Sus scrofa 29035 R-SSC-202723 https://reactome.org/PathwayBrowser/#/R-SSC-202723 Integrin alpha5beta1 binds FN1 dimer IEA Sus scrofa 29035 R-SSC-2046265 https://reactome.org/PathwayBrowser/#/R-SSC-2046265 B4GALTs transfer Gal to the keratan chain IEA Sus scrofa 29035 R-SSC-2046298 https://reactome.org/PathwayBrowser/#/R-SSC-2046298 B4GALTs transfer Gal to a branch of keratan IEA Sus scrofa 29035 R-SSC-2327746 https://reactome.org/PathwayBrowser/#/R-SSC-2327746 FN1 aggregation IEA Sus scrofa 29035 R-SSC-2993802 https://reactome.org/PathwayBrowser/#/R-SSC-2993802 HLCS biotinylates PC:Mn2+ IEA Sus scrofa 29035 R-SSC-2993814 https://reactome.org/PathwayBrowser/#/R-SSC-2993814 HLCS biotinylates ACACA:Mn2+ IEA Sus scrofa 29035 R-SSC-3299680 https://reactome.org/PathwayBrowser/#/R-SSC-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Sus scrofa 29035 R-SSC-3323111 https://reactome.org/PathwayBrowser/#/R-SSC-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Sus scrofa 29035 R-SSC-354073 https://reactome.org/PathwayBrowser/#/R-SSC-354073 Autophosphorylation of PTK2 at Y397 IEA Sus scrofa 29035 R-SSC-354087 https://reactome.org/PathwayBrowser/#/R-SSC-354087 Recruitment of GRB2 to p-PTK2 IEA Sus scrofa 29035 R-SSC-354124 https://reactome.org/PathwayBrowser/#/R-SSC-354124 Phosphorylation of pPTK2 by SRC IEA Sus scrofa 29035 R-SSC-354149 https://reactome.org/PathwayBrowser/#/R-SSC-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Sus scrofa 29035 R-SSC-354165 https://reactome.org/PathwayBrowser/#/R-SSC-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Sus scrofa 29035 R-SSC-372693 https://reactome.org/PathwayBrowser/#/R-SSC-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Sus scrofa 29035 R-SSC-372697 https://reactome.org/PathwayBrowser/#/R-SSC-372697 Crk binding to p130cas IEA Sus scrofa 29035 R-SSC-372705 https://reactome.org/PathwayBrowser/#/R-SSC-372705 Recruitment of BCAR1 to PTK2 complex IEA Sus scrofa 29035 R-SSC-377640 https://reactome.org/PathwayBrowser/#/R-SSC-377640 Autophosphorylation of SRC IEA Sus scrofa 29035 R-SSC-377641 https://reactome.org/PathwayBrowser/#/R-SSC-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Sus scrofa 29035 R-SSC-377643 https://reactome.org/PathwayBrowser/#/R-SSC-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Sus scrofa 29035 R-SSC-377644 https://reactome.org/PathwayBrowser/#/R-SSC-377644 Release of CSK from SRC IEA Sus scrofa 29035 R-SSC-4167511 https://reactome.org/PathwayBrowser/#/R-SSC-4167511 HLCS biotinylates ACACB IEA Sus scrofa 29035 R-SSC-429415 https://reactome.org/PathwayBrowser/#/R-SSC-429415 SYK binds to integrin alphaIIb beta3 IEA Sus scrofa 29035 R-SSC-429441 https://reactome.org/PathwayBrowser/#/R-SSC-429441 SYK activation by SRC IEA Sus scrofa 29035 R-SSC-435171 https://reactome.org/PathwayBrowser/#/R-SSC-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Sus scrofa 29035 R-SSC-450984 https://reactome.org/PathwayBrowser/#/R-SSC-450984 IDH2 dimer decarboxylates isocitrate IEA Sus scrofa 29035 R-SSC-452036 https://reactome.org/PathwayBrowser/#/R-SSC-452036 arginine + H2O => ornithine + urea [ARG2] IEA Sus scrofa 29035 R-SSC-453339 https://reactome.org/PathwayBrowser/#/R-SSC-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Sus scrofa 29035 R-SSC-5653886 https://reactome.org/PathwayBrowser/#/R-SSC-5653886 B4GALT1 binds LALBA IEA Sus scrofa 29035 R-SSC-5655835 https://reactome.org/PathwayBrowser/#/R-SSC-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Sus scrofa 29035 R-SSC-5655892 https://reactome.org/PathwayBrowser/#/R-SSC-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Sus scrofa 29035 R-SSC-5655965 https://reactome.org/PathwayBrowser/#/R-SSC-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Sus scrofa 29035 R-SSC-5672972 https://reactome.org/PathwayBrowser/#/R-SSC-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Sus scrofa 29035 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 29035 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 29035 R-SSC-5672980 https://reactome.org/PathwayBrowser/#/R-SSC-5672980 Dissociation of RAS:RAF complex IEA Sus scrofa 29035 R-SSC-5692462 https://reactome.org/PathwayBrowser/#/R-SSC-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Sus scrofa 29035 R-SSC-5693153 https://reactome.org/PathwayBrowser/#/R-SSC-5693153 PPM1K dephosphorylates p-BCKDH IEA Sus scrofa 29035 R-SSC-5696049 https://reactome.org/PathwayBrowser/#/R-SSC-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 29035 R-SSC-6798528 https://reactome.org/PathwayBrowser/#/R-SSC-6798528 S100A8:S100A9 binds Mn2+ IEA Sus scrofa 29035 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 29035 R-SSC-70569 https://reactome.org/PathwayBrowser/#/R-SSC-70569 arginine + H2O => ornithine + urea [ARG1] IEA Sus scrofa 29035 R-SSC-70967 https://reactome.org/PathwayBrowser/#/R-SSC-70967 IDH3 complex decarboxylates isocitrate IEA Sus scrofa 29035 R-SSC-71552 https://reactome.org/PathwayBrowser/#/R-SSC-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Sus scrofa 29035 R-SSC-71590 https://reactome.org/PathwayBrowser/#/R-SSC-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Sus scrofa 29035 R-SSC-71593 https://reactome.org/PathwayBrowser/#/R-SSC-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Sus scrofa 29035 R-SSC-75851 https://reactome.org/PathwayBrowser/#/R-SSC-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 29035 R-SSC-880007 https://reactome.org/PathwayBrowser/#/R-SSC-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa 29035 R-SSC-8876889 https://reactome.org/PathwayBrowser/#/R-SSC-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 29035 R-SSC-9012036 https://reactome.org/PathwayBrowser/#/R-SSC-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Sus scrofa 29035 R-SSC-9036727 https://reactome.org/PathwayBrowser/#/R-SSC-9036727 GAA hydrolyzes lysosomal glycogen IEA Sus scrofa 29035 R-SSC-9638064 https://reactome.org/PathwayBrowser/#/R-SSC-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Sus scrofa 29035 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa 29035 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa 29035 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 29035 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa 29035 R-SSC-9753632 https://reactome.org/PathwayBrowser/#/R-SSC-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Sus scrofa 29035 R-SSC-975919 https://reactome.org/PathwayBrowser/#/R-SSC-975919 Addition of galactose by beta 4-galactosyltransferases IEA Sus scrofa 29035 R-SSC-9851347 https://reactome.org/PathwayBrowser/#/R-SSC-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Sus scrofa 29035 R-SSC-9854415 https://reactome.org/PathwayBrowser/#/R-SSC-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Sus scrofa 29035 R-SSC-9854463 https://reactome.org/PathwayBrowser/#/R-SSC-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Sus scrofa 29035 R-SSC-9861631 https://reactome.org/PathwayBrowser/#/R-SSC-9861631 ME1 tetramerizes IEA Sus scrofa 29035 R-SSC-9861660 https://reactome.org/PathwayBrowser/#/R-SSC-9861660 ME1 tetramer decarboxylates OA to PYR IEA Sus scrofa 29035 R-XTR-1247910 https://reactome.org/PathwayBrowser/#/R-XTR-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Xenopus tropicalis 29035 R-XTR-1482961 https://reactome.org/PathwayBrowser/#/R-XTR-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Xenopus tropicalis 29035 R-XTR-1482962 https://reactome.org/PathwayBrowser/#/R-XTR-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Xenopus tropicalis 29035 R-XTR-1482973 https://reactome.org/PathwayBrowser/#/R-XTR-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Xenopus tropicalis 29035 R-XTR-1482976 https://reactome.org/PathwayBrowser/#/R-XTR-1482976 CDP-DAG is converted to PI by CDIPT IEA Xenopus tropicalis 29035 R-XTR-1855165 https://reactome.org/PathwayBrowser/#/R-XTR-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 29035 R-XTR-1855166 https://reactome.org/PathwayBrowser/#/R-XTR-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Xenopus tropicalis 29035 R-XTR-1855198 https://reactome.org/PathwayBrowser/#/R-XTR-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 29035 R-XTR-1889955 https://reactome.org/PathwayBrowser/#/R-XTR-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Xenopus tropicalis 29035 R-XTR-2023971 https://reactome.org/PathwayBrowser/#/R-XTR-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 29035 R-XTR-2023973 https://reactome.org/PathwayBrowser/#/R-XTR-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 29035 R-XTR-2025723 https://reactome.org/PathwayBrowser/#/R-XTR-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Xenopus tropicalis 29035 R-XTR-202723 https://reactome.org/PathwayBrowser/#/R-XTR-202723 Integrin alpha5beta1 binds FN1 dimer IEA Xenopus tropicalis 29035 R-XTR-2046265 https://reactome.org/PathwayBrowser/#/R-XTR-2046265 B4GALTs transfer Gal to the keratan chain IEA Xenopus tropicalis 29035 R-XTR-2046298 https://reactome.org/PathwayBrowser/#/R-XTR-2046298 B4GALTs transfer Gal to a branch of keratan IEA Xenopus tropicalis 29035 R-XTR-2327746 https://reactome.org/PathwayBrowser/#/R-XTR-2327746 FN1 aggregation IEA Xenopus tropicalis 29035 R-XTR-2993802 https://reactome.org/PathwayBrowser/#/R-XTR-2993802 HLCS biotinylates PC:Mn2+ IEA Xenopus tropicalis 29035 R-XTR-2993814 https://reactome.org/PathwayBrowser/#/R-XTR-2993814 HLCS biotinylates ACACA:Mn2+ IEA Xenopus tropicalis 29035 R-XTR-3299680 https://reactome.org/PathwayBrowser/#/R-XTR-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Xenopus tropicalis 29035 R-XTR-3323111 https://reactome.org/PathwayBrowser/#/R-XTR-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Xenopus tropicalis 29035 R-XTR-4167511 https://reactome.org/PathwayBrowser/#/R-XTR-4167511 HLCS biotinylates ACACB IEA Xenopus tropicalis 29035 R-XTR-435171 https://reactome.org/PathwayBrowser/#/R-XTR-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Xenopus tropicalis 29035 R-XTR-450984 https://reactome.org/PathwayBrowser/#/R-XTR-450984 IDH2 dimer decarboxylates isocitrate IEA Xenopus tropicalis 29035 R-XTR-452036 https://reactome.org/PathwayBrowser/#/R-XTR-452036 arginine + H2O => ornithine + urea [ARG2] IEA Xenopus tropicalis 29035 R-XTR-453339 https://reactome.org/PathwayBrowser/#/R-XTR-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Xenopus tropicalis 29035 R-XTR-5653886 https://reactome.org/PathwayBrowser/#/R-XTR-5653886 B4GALT1 binds LALBA IEA Xenopus tropicalis 29035 R-XTR-5655892 https://reactome.org/PathwayBrowser/#/R-XTR-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Xenopus tropicalis 29035 R-XTR-5655965 https://reactome.org/PathwayBrowser/#/R-XTR-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Xenopus tropicalis 29035 R-XTR-5692462 https://reactome.org/PathwayBrowser/#/R-XTR-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Xenopus tropicalis 29035 R-XTR-5696049 https://reactome.org/PathwayBrowser/#/R-XTR-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 29035 R-XTR-6798528 https://reactome.org/PathwayBrowser/#/R-XTR-6798528 S100A8:S100A9 binds Mn2+ IEA Xenopus tropicalis 29035 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 29035 R-XTR-70569 https://reactome.org/PathwayBrowser/#/R-XTR-70569 arginine + H2O => ornithine + urea [ARG1] IEA Xenopus tropicalis 29035 R-XTR-71552 https://reactome.org/PathwayBrowser/#/R-XTR-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Xenopus tropicalis 29035 R-XTR-71590 https://reactome.org/PathwayBrowser/#/R-XTR-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Xenopus tropicalis 29035 R-XTR-71593 https://reactome.org/PathwayBrowser/#/R-XTR-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Xenopus tropicalis 29035 R-XTR-75851 https://reactome.org/PathwayBrowser/#/R-XTR-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 29035 R-XTR-880007 https://reactome.org/PathwayBrowser/#/R-XTR-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Xenopus tropicalis 29035 R-XTR-8876889 https://reactome.org/PathwayBrowser/#/R-XTR-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 29035 R-XTR-8959798 https://reactome.org/PathwayBrowser/#/R-XTR-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region IEA Xenopus tropicalis 29035 R-XTR-9033959 https://reactome.org/PathwayBrowser/#/R-XTR-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Xenopus tropicalis 29035 R-XTR-9033961 https://reactome.org/PathwayBrowser/#/R-XTR-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Xenopus tropicalis 29035 R-XTR-9034042 https://reactome.org/PathwayBrowser/#/R-XTR-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Xenopus tropicalis 29035 R-XTR-9034053 https://reactome.org/PathwayBrowser/#/R-XTR-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Xenopus tropicalis 29035 R-XTR-9638064 https://reactome.org/PathwayBrowser/#/R-XTR-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Xenopus tropicalis 29035 R-XTR-9753632 https://reactome.org/PathwayBrowser/#/R-XTR-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Xenopus tropicalis 29035 R-XTR-975919 https://reactome.org/PathwayBrowser/#/R-XTR-975919 Addition of galactose by beta 4-galactosyltransferases IEA Xenopus tropicalis 29035 R-XTR-9851347 https://reactome.org/PathwayBrowser/#/R-XTR-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Xenopus tropicalis 29035 R-XTR-9854415 https://reactome.org/PathwayBrowser/#/R-XTR-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Xenopus tropicalis 29036 R-BTA-2002466 https://reactome.org/PathwayBrowser/#/R-BTA-2002466 Formation of allysine by LOX IEA Bos taurus 29036 R-BTA-2129375 https://reactome.org/PathwayBrowser/#/R-BTA-2129375 Elastin cross-linking by lysyl oxidase IEA Bos taurus 29036 R-BTA-2395340 https://reactome.org/PathwayBrowser/#/R-BTA-2395340 Formation of hydroxyallysine by LOX IEA Bos taurus 29036 R-BTA-3299682 https://reactome.org/PathwayBrowser/#/R-BTA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Bos taurus 29036 R-BTA-3299691 https://reactome.org/PathwayBrowser/#/R-BTA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Bos taurus 29036 R-BTA-3299753 https://reactome.org/PathwayBrowser/#/R-BTA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Bos taurus 29036 R-BTA-3777112 https://reactome.org/PathwayBrowser/#/R-BTA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Bos taurus 29036 R-BTA-437300 https://reactome.org/PathwayBrowser/#/R-BTA-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Bos taurus 29036 R-BTA-4837364 https://reactome.org/PathwayBrowser/#/R-BTA-4837364 Secretion of SOD3 IEA Bos taurus 29036 R-BTA-5662613 https://reactome.org/PathwayBrowser/#/R-BTA-5662613 MT3 exchanges zinc for copper IEA Bos taurus 29036 R-BTA-5662662 https://reactome.org/PathwayBrowser/#/R-BTA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Bos taurus 29036 R-BTA-5662692 https://reactome.org/PathwayBrowser/#/R-BTA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Bos taurus 29036 R-BTA-5663050 https://reactome.org/PathwayBrowser/#/R-BTA-5663050 DHI and DHICA polymerize forming eumelanin IEA Bos taurus 29036 R-BTA-904830 https://reactome.org/PathwayBrowser/#/R-BTA-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Bos taurus 29036 R-BTA-917891 https://reactome.org/PathwayBrowser/#/R-BTA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Bos taurus 29036 R-CEL-3299691 https://reactome.org/PathwayBrowser/#/R-CEL-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Caenorhabditis elegans 29036 R-CEL-3777112 https://reactome.org/PathwayBrowser/#/R-CEL-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Caenorhabditis elegans 29036 R-CEL-437300 https://reactome.org/PathwayBrowser/#/R-CEL-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Caenorhabditis elegans 29036 R-CEL-5662662 https://reactome.org/PathwayBrowser/#/R-CEL-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Caenorhabditis elegans 29036 R-CEL-5662692 https://reactome.org/PathwayBrowser/#/R-CEL-5662692 Dopa is oxidized to dopaquinone by TYR IEA Caenorhabditis elegans 29036 R-CEL-5663050 https://reactome.org/PathwayBrowser/#/R-CEL-5663050 DHI and DHICA polymerize forming eumelanin IEA Caenorhabditis elegans 29036 R-CEL-936895 https://reactome.org/PathwayBrowser/#/R-CEL-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Caenorhabditis elegans 29036 R-CFA-2002466 https://reactome.org/PathwayBrowser/#/R-CFA-2002466 Formation of allysine by LOX IEA Canis familiaris 29036 R-CFA-2129375 https://reactome.org/PathwayBrowser/#/R-CFA-2129375 Elastin cross-linking by lysyl oxidase IEA Canis familiaris 29036 R-CFA-2395340 https://reactome.org/PathwayBrowser/#/R-CFA-2395340 Formation of hydroxyallysine by LOX IEA Canis familiaris 29036 R-CFA-3299682 https://reactome.org/PathwayBrowser/#/R-CFA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Canis familiaris 29036 R-CFA-3299691 https://reactome.org/PathwayBrowser/#/R-CFA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Canis familiaris 29036 R-CFA-3299753 https://reactome.org/PathwayBrowser/#/R-CFA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Canis familiaris 29036 R-CFA-3777112 https://reactome.org/PathwayBrowser/#/R-CFA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Canis familiaris 29036 R-CFA-437300 https://reactome.org/PathwayBrowser/#/R-CFA-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Canis familiaris 29036 R-CFA-4837364 https://reactome.org/PathwayBrowser/#/R-CFA-4837364 Secretion of SOD3 IEA Canis familiaris 29036 R-CFA-5662613 https://reactome.org/PathwayBrowser/#/R-CFA-5662613 MT3 exchanges zinc for copper IEA Canis familiaris 29036 R-CFA-5662662 https://reactome.org/PathwayBrowser/#/R-CFA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Canis familiaris 29036 R-CFA-5662692 https://reactome.org/PathwayBrowser/#/R-CFA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Canis familiaris 29036 R-CFA-5663050 https://reactome.org/PathwayBrowser/#/R-CFA-5663050 DHI and DHICA polymerize forming eumelanin IEA Canis familiaris 29036 R-CFA-904830 https://reactome.org/PathwayBrowser/#/R-CFA-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Canis familiaris 29036 R-CFA-917891 https://reactome.org/PathwayBrowser/#/R-CFA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Canis familiaris 29036 R-CFA-936802 https://reactome.org/PathwayBrowser/#/R-CFA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Canis familiaris 29036 R-CFA-936895 https://reactome.org/PathwayBrowser/#/R-CFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Canis familiaris 29036 R-DDI-3299682 https://reactome.org/PathwayBrowser/#/R-DDI-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Dictyostelium discoideum 29036 R-DDI-3299691 https://reactome.org/PathwayBrowser/#/R-DDI-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Dictyostelium discoideum 29036 R-DDI-3299753 https://reactome.org/PathwayBrowser/#/R-DDI-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Dictyostelium discoideum 29036 R-DDI-3777112 https://reactome.org/PathwayBrowser/#/R-DDI-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Dictyostelium discoideum 29036 R-DDI-437300 https://reactome.org/PathwayBrowser/#/R-DDI-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Dictyostelium discoideum 29036 R-DDI-4837364 https://reactome.org/PathwayBrowser/#/R-DDI-4837364 Secretion of SOD3 IEA Dictyostelium discoideum 29036 R-DDI-5662662 https://reactome.org/PathwayBrowser/#/R-DDI-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Dictyostelium discoideum 29036 R-DDI-5662692 https://reactome.org/PathwayBrowser/#/R-DDI-5662692 Dopa is oxidized to dopaquinone by TYR IEA Dictyostelium discoideum 29036 R-DDI-5663050 https://reactome.org/PathwayBrowser/#/R-DDI-5663050 DHI and DHICA polymerize forming eumelanin IEA Dictyostelium discoideum 29036 R-DDI-936895 https://reactome.org/PathwayBrowser/#/R-DDI-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Dictyostelium discoideum 29036 R-DME-3299691 https://reactome.org/PathwayBrowser/#/R-DME-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Drosophila melanogaster 29036 R-DME-3299753 https://reactome.org/PathwayBrowser/#/R-DME-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Drosophila melanogaster 29036 R-DME-3777112 https://reactome.org/PathwayBrowser/#/R-DME-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Drosophila melanogaster 29036 R-DME-437300 https://reactome.org/PathwayBrowser/#/R-DME-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Drosophila melanogaster 29036 R-DME-936895 https://reactome.org/PathwayBrowser/#/R-DME-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Drosophila melanogaster 29036 R-DRE-2002466 https://reactome.org/PathwayBrowser/#/R-DRE-2002466 Formation of allysine by LOX IEA Danio rerio 29036 R-DRE-2395340 https://reactome.org/PathwayBrowser/#/R-DRE-2395340 Formation of hydroxyallysine by LOX IEA Danio rerio 29036 R-DRE-3299682 https://reactome.org/PathwayBrowser/#/R-DRE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Danio rerio 29036 R-DRE-3299691 https://reactome.org/PathwayBrowser/#/R-DRE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Danio rerio 29036 R-DRE-3777112 https://reactome.org/PathwayBrowser/#/R-DRE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Danio rerio 29036 R-DRE-437300 https://reactome.org/PathwayBrowser/#/R-DRE-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Danio rerio 29036 R-DRE-4837364 https://reactome.org/PathwayBrowser/#/R-DRE-4837364 Secretion of SOD3 IEA Danio rerio 29036 R-DRE-5662613 https://reactome.org/PathwayBrowser/#/R-DRE-5662613 MT3 exchanges zinc for copper IEA Danio rerio 29036 R-DRE-904830 https://reactome.org/PathwayBrowser/#/R-DRE-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Danio rerio 29036 R-DRE-917891 https://reactome.org/PathwayBrowser/#/R-DRE-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Danio rerio 29036 R-DRE-936802 https://reactome.org/PathwayBrowser/#/R-DRE-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Danio rerio 29036 R-GGA-2002466 https://reactome.org/PathwayBrowser/#/R-GGA-2002466 Formation of allysine by LOX IEA Gallus gallus 29036 R-GGA-2129375 https://reactome.org/PathwayBrowser/#/R-GGA-2129375 Elastin cross-linking by lysyl oxidase IEA Gallus gallus 29036 R-GGA-2395340 https://reactome.org/PathwayBrowser/#/R-GGA-2395340 Formation of hydroxyallysine by LOX IEA Gallus gallus 29036 R-GGA-3299682 https://reactome.org/PathwayBrowser/#/R-GGA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Gallus gallus 29036 R-GGA-3299691 https://reactome.org/PathwayBrowser/#/R-GGA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Gallus gallus 29036 R-GGA-3299753 https://reactome.org/PathwayBrowser/#/R-GGA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Gallus gallus 29036 R-GGA-3777112 https://reactome.org/PathwayBrowser/#/R-GGA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Gallus gallus 29036 R-GGA-437300 https://reactome.org/PathwayBrowser/#/R-GGA-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Gallus gallus 29036 R-GGA-4837364 https://reactome.org/PathwayBrowser/#/R-GGA-4837364 Secretion of SOD3 IEA Gallus gallus 29036 R-GGA-5662613 https://reactome.org/PathwayBrowser/#/R-GGA-5662613 MT3 exchanges zinc for copper IEA Gallus gallus 29036 R-GGA-5662662 https://reactome.org/PathwayBrowser/#/R-GGA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Gallus gallus 29036 R-GGA-5662692 https://reactome.org/PathwayBrowser/#/R-GGA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Gallus gallus 29036 R-GGA-5663050 https://reactome.org/PathwayBrowser/#/R-GGA-5663050 DHI and DHICA polymerize forming eumelanin IEA Gallus gallus 29036 R-GGA-904830 https://reactome.org/PathwayBrowser/#/R-GGA-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Gallus gallus 29036 R-GGA-917891 https://reactome.org/PathwayBrowser/#/R-GGA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Gallus gallus 29036 R-GGA-936802 https://reactome.org/PathwayBrowser/#/R-GGA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Gallus gallus 29036 R-GGA-936895 https://reactome.org/PathwayBrowser/#/R-GGA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Gallus gallus 29036 R-HSA-1222469 https://reactome.org/PathwayBrowser/#/R-HSA-1222469 SodC reduces superoxide to H2O2 TAS Homo sapiens 29036 R-HSA-2002466 https://reactome.org/PathwayBrowser/#/R-HSA-2002466 Formation of allysine by LOX TAS Homo sapiens 29036 R-HSA-2129375 https://reactome.org/PathwayBrowser/#/R-HSA-2129375 Elastin cross-linking by lysyl oxidase TAS Homo sapiens 29036 R-HSA-2395340 https://reactome.org/PathwayBrowser/#/R-HSA-2395340 Formation of hydroxyallysine by LOX TAS Homo sapiens 29036 R-HSA-3299682 https://reactome.org/PathwayBrowser/#/R-HSA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) TAS Homo sapiens 29036 R-HSA-3299691 https://reactome.org/PathwayBrowser/#/R-HSA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) TAS Homo sapiens 29036 R-HSA-3299753 https://reactome.org/PathwayBrowser/#/R-HSA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 TAS Homo sapiens 29036 R-HSA-3697838 https://reactome.org/PathwayBrowser/#/R-HSA-3697838 ATP7A transfers Cu from ATOX1 to SOD3 IEA Homo sapiens 29036 R-HSA-3777112 https://reactome.org/PathwayBrowser/#/R-HSA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) TAS Homo sapiens 29036 R-HSA-3780979 https://reactome.org/PathwayBrowser/#/R-HSA-3780979 CCS transfers Cu to SOD1 (mitochondrial) IEA Homo sapiens 29036 R-HSA-437300 https://reactome.org/PathwayBrowser/#/R-HSA-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol TAS Homo sapiens 29036 R-HSA-4837364 https://reactome.org/PathwayBrowser/#/R-HSA-4837364 Secretion of SOD3 TAS Homo sapiens 29036 R-HSA-5621402 https://reactome.org/PathwayBrowser/#/R-HSA-5621402 Defective CP does not oxidise Fe2+ to Fe3+ TAS Homo sapiens 29036 R-HSA-5655733 https://reactome.org/PathwayBrowser/#/R-HSA-5655733 Defective SLC40A1 does not transport Fe2+ from cytosol to extracellular region TAS Homo sapiens 29036 R-HSA-5662613 https://reactome.org/PathwayBrowser/#/R-HSA-5662613 MT3 exchanges zinc for copper TAS Homo sapiens 29036 R-HSA-5662662 https://reactome.org/PathwayBrowser/#/R-HSA-5662662 Tyrosinase oxidises tyrosine to dopaquinone TAS Homo sapiens 29036 R-HSA-5662692 https://reactome.org/PathwayBrowser/#/R-HSA-5662692 Dopa is oxidized to dopaquinone by TYR TAS Homo sapiens 29036 R-HSA-5663050 https://reactome.org/PathwayBrowser/#/R-HSA-5663050 DHI and DHICA polymerize forming eumelanin TAS Homo sapiens 29036 R-HSA-904830 https://reactome.org/PathwayBrowser/#/R-HSA-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region TAS Homo sapiens 29036 R-HSA-917891 https://reactome.org/PathwayBrowser/#/R-HSA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ TAS Homo sapiens 29036 R-HSA-936802 https://reactome.org/PathwayBrowser/#/R-HSA-936802 ATP7A transports cytosolic Cu2+ to extracellular region TAS Homo sapiens 29036 R-HSA-936895 https://reactome.org/PathwayBrowser/#/R-HSA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen TAS Homo sapiens 29036 R-MMU-2002466 https://reactome.org/PathwayBrowser/#/R-MMU-2002466 Formation of allysine by LOX IEA Mus musculus 29036 R-MMU-2129375 https://reactome.org/PathwayBrowser/#/R-MMU-2129375 Elastin cross-linking by lysyl oxidase IEA Mus musculus 29036 R-MMU-2395340 https://reactome.org/PathwayBrowser/#/R-MMU-2395340 Formation of hydroxyallysine by LOX IEA Mus musculus 29036 R-MMU-3299682 https://reactome.org/PathwayBrowser/#/R-MMU-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Mus musculus 29036 R-MMU-3299691 https://reactome.org/PathwayBrowser/#/R-MMU-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Mus musculus 29036 R-MMU-3299753 https://reactome.org/PathwayBrowser/#/R-MMU-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Mus musculus 29036 R-MMU-3697899 https://reactome.org/PathwayBrowser/#/R-MMU-3697899 Atp7a transfers Cu from Atox1 to Sod3 TAS Mus musculus 29036 R-MMU-3777112 https://reactome.org/PathwayBrowser/#/R-MMU-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Mus musculus 29036 R-MMU-3780963 https://reactome.org/PathwayBrowser/#/R-MMU-3780963 Ccs transfers Cu to Sod1 TAS Mus musculus 29036 R-MMU-437300 https://reactome.org/PathwayBrowser/#/R-MMU-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Mus musculus 29036 R-MMU-4837364 https://reactome.org/PathwayBrowser/#/R-MMU-4837364 Secretion of SOD3 IEA Mus musculus 29036 R-MMU-5662613 https://reactome.org/PathwayBrowser/#/R-MMU-5662613 MT3 exchanges zinc for copper IEA Mus musculus 29036 R-MMU-5662662 https://reactome.org/PathwayBrowser/#/R-MMU-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Mus musculus 29036 R-MMU-5662692 https://reactome.org/PathwayBrowser/#/R-MMU-5662692 Dopa is oxidized to dopaquinone by TYR IEA Mus musculus 29036 R-MMU-5663050 https://reactome.org/PathwayBrowser/#/R-MMU-5663050 DHI and DHICA polymerize forming eumelanin IEA Mus musculus 29036 R-MMU-904830 https://reactome.org/PathwayBrowser/#/R-MMU-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Mus musculus 29036 R-MMU-917891 https://reactome.org/PathwayBrowser/#/R-MMU-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Mus musculus 29036 R-MMU-936802 https://reactome.org/PathwayBrowser/#/R-MMU-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Mus musculus 29036 R-MMU-936895 https://reactome.org/PathwayBrowser/#/R-MMU-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Mus musculus 29036 R-PFA-437300 https://reactome.org/PathwayBrowser/#/R-PFA-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Plasmodium falciparum 29036 R-PFA-936895 https://reactome.org/PathwayBrowser/#/R-PFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Plasmodium falciparum 29036 R-RNO-2002466 https://reactome.org/PathwayBrowser/#/R-RNO-2002466 Formation of allysine by LOX IEA Rattus norvegicus 29036 R-RNO-2129375 https://reactome.org/PathwayBrowser/#/R-RNO-2129375 Elastin cross-linking by lysyl oxidase IEA Rattus norvegicus 29036 R-RNO-2395340 https://reactome.org/PathwayBrowser/#/R-RNO-2395340 Formation of hydroxyallysine by LOX IEA Rattus norvegicus 29036 R-RNO-3299682 https://reactome.org/PathwayBrowser/#/R-RNO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Rattus norvegicus 29036 R-RNO-3299691 https://reactome.org/PathwayBrowser/#/R-RNO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Rattus norvegicus 29036 R-RNO-3299753 https://reactome.org/PathwayBrowser/#/R-RNO-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Rattus norvegicus 29036 R-RNO-3777112 https://reactome.org/PathwayBrowser/#/R-RNO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Rattus norvegicus 29036 R-RNO-437300 https://reactome.org/PathwayBrowser/#/R-RNO-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Rattus norvegicus 29036 R-RNO-4837364 https://reactome.org/PathwayBrowser/#/R-RNO-4837364 Secretion of SOD3 IEA Rattus norvegicus 29036 R-RNO-5662613 https://reactome.org/PathwayBrowser/#/R-RNO-5662613 MT3 exchanges zinc for copper IEA Rattus norvegicus 29036 R-RNO-5662662 https://reactome.org/PathwayBrowser/#/R-RNO-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Rattus norvegicus 29036 R-RNO-5662692 https://reactome.org/PathwayBrowser/#/R-RNO-5662692 Dopa is oxidized to dopaquinone by TYR IEA Rattus norvegicus 29036 R-RNO-5663050 https://reactome.org/PathwayBrowser/#/R-RNO-5663050 DHI and DHICA polymerize forming eumelanin IEA Rattus norvegicus 29036 R-RNO-904830 https://reactome.org/PathwayBrowser/#/R-RNO-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Rattus norvegicus 29036 R-RNO-917891 https://reactome.org/PathwayBrowser/#/R-RNO-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Rattus norvegicus 29036 R-RNO-936802 https://reactome.org/PathwayBrowser/#/R-RNO-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Rattus norvegicus 29036 R-RNO-936895 https://reactome.org/PathwayBrowser/#/R-RNO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Rattus norvegicus 29036 R-SCE-3299682 https://reactome.org/PathwayBrowser/#/R-SCE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Saccharomyces cerevisiae 29036 R-SCE-3299691 https://reactome.org/PathwayBrowser/#/R-SCE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Saccharomyces cerevisiae 29036 R-SCE-3299753 https://reactome.org/PathwayBrowser/#/R-SCE-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Saccharomyces cerevisiae 29036 R-SCE-3777112 https://reactome.org/PathwayBrowser/#/R-SCE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Saccharomyces cerevisiae 29036 R-SCE-437300 https://reactome.org/PathwayBrowser/#/R-SCE-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 29036 R-SCE-4837364 https://reactome.org/PathwayBrowser/#/R-SCE-4837364 Secretion of SOD3 IEA Saccharomyces cerevisiae 29036 R-SCE-936895 https://reactome.org/PathwayBrowser/#/R-SCE-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Saccharomyces cerevisiae 29036 R-SPO-3299682 https://reactome.org/PathwayBrowser/#/R-SPO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Schizosaccharomyces pombe 29036 R-SPO-3299691 https://reactome.org/PathwayBrowser/#/R-SPO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Schizosaccharomyces pombe 29036 R-SPO-3777112 https://reactome.org/PathwayBrowser/#/R-SPO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Schizosaccharomyces pombe 29036 R-SPO-437300 https://reactome.org/PathwayBrowser/#/R-SPO-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Schizosaccharomyces pombe 29036 R-SPO-4837364 https://reactome.org/PathwayBrowser/#/R-SPO-4837364 Secretion of SOD3 IEA Schizosaccharomyces pombe 29036 R-SPO-936895 https://reactome.org/PathwayBrowser/#/R-SPO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Schizosaccharomyces pombe 29036 R-SSC-2002466 https://reactome.org/PathwayBrowser/#/R-SSC-2002466 Formation of allysine by LOX IEA Sus scrofa 29036 R-SSC-2129375 https://reactome.org/PathwayBrowser/#/R-SSC-2129375 Elastin cross-linking by lysyl oxidase IEA Sus scrofa 29036 R-SSC-2395340 https://reactome.org/PathwayBrowser/#/R-SSC-2395340 Formation of hydroxyallysine by LOX IEA Sus scrofa 29036 R-SSC-3299682 https://reactome.org/PathwayBrowser/#/R-SSC-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Sus scrofa 29036 R-SSC-3299691 https://reactome.org/PathwayBrowser/#/R-SSC-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Sus scrofa 29036 R-SSC-3299753 https://reactome.org/PathwayBrowser/#/R-SSC-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Sus scrofa 29036 R-SSC-3777112 https://reactome.org/PathwayBrowser/#/R-SSC-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Sus scrofa 29036 R-SSC-437300 https://reactome.org/PathwayBrowser/#/R-SSC-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Sus scrofa 29036 R-SSC-4837364 https://reactome.org/PathwayBrowser/#/R-SSC-4837364 Secretion of SOD3 IEA Sus scrofa 29036 R-SSC-5662613 https://reactome.org/PathwayBrowser/#/R-SSC-5662613 MT3 exchanges zinc for copper IEA Sus scrofa 29036 R-SSC-5662662 https://reactome.org/PathwayBrowser/#/R-SSC-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Sus scrofa 29036 R-SSC-5662692 https://reactome.org/PathwayBrowser/#/R-SSC-5662692 Dopa is oxidized to dopaquinone by TYR IEA Sus scrofa 29036 R-SSC-5663050 https://reactome.org/PathwayBrowser/#/R-SSC-5663050 DHI and DHICA polymerize forming eumelanin IEA Sus scrofa 29036 R-SSC-904830 https://reactome.org/PathwayBrowser/#/R-SSC-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Sus scrofa 29036 R-SSC-917891 https://reactome.org/PathwayBrowser/#/R-SSC-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Sus scrofa 29036 R-SSC-936802 https://reactome.org/PathwayBrowser/#/R-SSC-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Sus scrofa 29036 R-XTR-2002466 https://reactome.org/PathwayBrowser/#/R-XTR-2002466 Formation of allysine by LOX IEA Xenopus tropicalis 29036 R-XTR-2395340 https://reactome.org/PathwayBrowser/#/R-XTR-2395340 Formation of hydroxyallysine by LOX IEA Xenopus tropicalis 29036 R-XTR-3299682 https://reactome.org/PathwayBrowser/#/R-XTR-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Xenopus tropicalis 29036 R-XTR-3299691 https://reactome.org/PathwayBrowser/#/R-XTR-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Xenopus tropicalis 29036 R-XTR-3299753 https://reactome.org/PathwayBrowser/#/R-XTR-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Xenopus tropicalis 29036 R-XTR-3777112 https://reactome.org/PathwayBrowser/#/R-XTR-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Xenopus tropicalis 29036 R-XTR-437300 https://reactome.org/PathwayBrowser/#/R-XTR-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Xenopus tropicalis 29036 R-XTR-4837364 https://reactome.org/PathwayBrowser/#/R-XTR-4837364 Secretion of SOD3 IEA Xenopus tropicalis 29036 R-XTR-5662662 https://reactome.org/PathwayBrowser/#/R-XTR-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Xenopus tropicalis 29036 R-XTR-5662692 https://reactome.org/PathwayBrowser/#/R-XTR-5662692 Dopa is oxidized to dopaquinone by TYR IEA Xenopus tropicalis 29036 R-XTR-5663050 https://reactome.org/PathwayBrowser/#/R-XTR-5663050 DHI and DHICA polymerize forming eumelanin IEA Xenopus tropicalis 29036 R-XTR-904830 https://reactome.org/PathwayBrowser/#/R-XTR-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Xenopus tropicalis 29036 R-XTR-917891 https://reactome.org/PathwayBrowser/#/R-XTR-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Xenopus tropicalis 29036 R-XTR-936802 https://reactome.org/PathwayBrowser/#/R-XTR-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Xenopus tropicalis 29036 R-XTR-936895 https://reactome.org/PathwayBrowser/#/R-XTR-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Xenopus tropicalis 2904 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 2904 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 2904 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 2904 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 2904 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 2904 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 2904 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 2904 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 2904 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 2904 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 2904 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 2904 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 2904 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 2904 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 2904 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 2904 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 2904 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 2904 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 2904 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 2904 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 2904 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 2904 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 2904 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 2904 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 2904 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 2904 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 2904 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 2904 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 2904 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 2904 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 2904 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 2904 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 2904 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 2904 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 2904 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 2904 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 2904 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 29073 R-BTA-1650808 https://reactome.org/PathwayBrowser/#/R-BTA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Bos taurus 29073 R-BTA-1980233 https://reactome.org/PathwayBrowser/#/R-BTA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Bos taurus 29073 R-CEL-1650808 https://reactome.org/PathwayBrowser/#/R-CEL-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Caenorhabditis elegans 29073 R-CFA-1650808 https://reactome.org/PathwayBrowser/#/R-CFA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Canis familiaris 29073 R-CFA-1980233 https://reactome.org/PathwayBrowser/#/R-CFA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Canis familiaris 29073 R-DRE-1650808 https://reactome.org/PathwayBrowser/#/R-DRE-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Danio rerio 29073 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus 29073 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus 29073 R-HSA-1650808 https://reactome.org/PathwayBrowser/#/R-HSA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines TAS Homo sapiens 29073 R-HSA-1980233 https://reactome.org/PathwayBrowser/#/R-HSA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen TAS Homo sapiens 29073 R-HSA-8948226 https://reactome.org/PathwayBrowser/#/R-HSA-8948226 Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates TAS Homo sapiens 29073 R-HSA-8948230 https://reactome.org/PathwayBrowser/#/R-HSA-8948230 P3HB binds 4-Hyp-collagen propeptides TAS Homo sapiens 29073 R-MMU-1650808 https://reactome.org/PathwayBrowser/#/R-MMU-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Mus musculus 29073 R-MMU-1980233 https://reactome.org/PathwayBrowser/#/R-MMU-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Mus musculus 29073 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus 29073 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus 29073 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa 29073 R-XTR-1650808 https://reactome.org/PathwayBrowser/#/R-XTR-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Xenopus tropicalis 29073 R-XTR-1980233 https://reactome.org/PathwayBrowser/#/R-XTR-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Xenopus tropicalis 29089 R-BTA-426240 https://reactome.org/PathwayBrowser/#/R-BTA-426240 DAG kinase produces phosphatidic acid from DAG IEA Bos taurus 29089 R-BTA-5221130 https://reactome.org/PathwayBrowser/#/R-BTA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Bos taurus 29089 R-BTA-75899 https://reactome.org/PathwayBrowser/#/R-BTA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Bos taurus 29089 R-CEL-426240 https://reactome.org/PathwayBrowser/#/R-CEL-426240 DAG kinase produces phosphatidic acid from DAG IEA Caenorhabditis elegans 29089 R-CEL-5221130 https://reactome.org/PathwayBrowser/#/R-CEL-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Caenorhabditis elegans 29089 R-CEL-75899 https://reactome.org/PathwayBrowser/#/R-CEL-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Caenorhabditis elegans 29089 R-CFA-426240 https://reactome.org/PathwayBrowser/#/R-CFA-426240 DAG kinase produces phosphatidic acid from DAG IEA Canis familiaris 29089 R-CFA-5221130 https://reactome.org/PathwayBrowser/#/R-CFA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Canis familiaris 29089 R-CFA-75899 https://reactome.org/PathwayBrowser/#/R-CFA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Canis familiaris 29089 R-DDI-426240 https://reactome.org/PathwayBrowser/#/R-DDI-426240 DAG kinase produces phosphatidic acid from DAG IEA Dictyostelium discoideum 29089 R-DDI-5221130 https://reactome.org/PathwayBrowser/#/R-DDI-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Dictyostelium discoideum 29089 R-DDI-75899 https://reactome.org/PathwayBrowser/#/R-DDI-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Dictyostelium discoideum 29089 R-DME-426240 https://reactome.org/PathwayBrowser/#/R-DME-426240 DAG kinase produces phosphatidic acid from DAG IEA Drosophila melanogaster 29089 R-DME-5221130 https://reactome.org/PathwayBrowser/#/R-DME-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Drosophila melanogaster 29089 R-DME-75899 https://reactome.org/PathwayBrowser/#/R-DME-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Drosophila melanogaster 29089 R-GGA-426240 https://reactome.org/PathwayBrowser/#/R-GGA-426240 DAG kinase produces phosphatidic acid from DAG IEA Gallus gallus 29089 R-GGA-5221130 https://reactome.org/PathwayBrowser/#/R-GGA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Gallus gallus 29089 R-GGA-75899 https://reactome.org/PathwayBrowser/#/R-GGA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Gallus gallus 29089 R-HSA-426240 https://reactome.org/PathwayBrowser/#/R-HSA-426240 DAG kinase produces phosphatidic acid from DAG TAS Homo sapiens 29089 R-HSA-5221130 https://reactome.org/PathwayBrowser/#/R-HSA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol TAS Homo sapiens 29089 R-HSA-75899 https://reactome.org/PathwayBrowser/#/R-HSA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate TAS Homo sapiens 29089 R-MMU-426240 https://reactome.org/PathwayBrowser/#/R-MMU-426240 DAG kinase produces phosphatidic acid from DAG IEA Mus musculus 29089 R-MMU-5221130 https://reactome.org/PathwayBrowser/#/R-MMU-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Mus musculus 29089 R-MMU-75899 https://reactome.org/PathwayBrowser/#/R-MMU-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Mus musculus 29089 R-PFA-426240 https://reactome.org/PathwayBrowser/#/R-PFA-426240 DAG kinase produces phosphatidic acid from DAG IEA Plasmodium falciparum 29089 R-PFA-5221130 https://reactome.org/PathwayBrowser/#/R-PFA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Plasmodium falciparum 29089 R-PFA-75899 https://reactome.org/PathwayBrowser/#/R-PFA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Plasmodium falciparum 29089 R-RNO-426240 https://reactome.org/PathwayBrowser/#/R-RNO-426240 DAG kinase produces phosphatidic acid from DAG IEA Rattus norvegicus 29089 R-RNO-5221130 https://reactome.org/PathwayBrowser/#/R-RNO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Rattus norvegicus 29089 R-RNO-75899 https://reactome.org/PathwayBrowser/#/R-RNO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Rattus norvegicus 29089 R-SCE-5221130 https://reactome.org/PathwayBrowser/#/R-SCE-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Saccharomyces cerevisiae 29089 R-SCE-75899 https://reactome.org/PathwayBrowser/#/R-SCE-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Saccharomyces cerevisiae 29089 R-SPO-5221130 https://reactome.org/PathwayBrowser/#/R-SPO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Schizosaccharomyces pombe 29089 R-SPO-75899 https://reactome.org/PathwayBrowser/#/R-SPO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Schizosaccharomyces pombe 29089 R-SSC-426240 https://reactome.org/PathwayBrowser/#/R-SSC-426240 DAG kinase produces phosphatidic acid from DAG IEA Sus scrofa 29089 R-SSC-5221130 https://reactome.org/PathwayBrowser/#/R-SSC-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Sus scrofa 29089 R-SSC-75899 https://reactome.org/PathwayBrowser/#/R-SSC-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Sus scrofa 29089 R-XTR-426240 https://reactome.org/PathwayBrowser/#/R-XTR-426240 DAG kinase produces phosphatidic acid from DAG IEA Xenopus tropicalis 29089 R-XTR-5221130 https://reactome.org/PathwayBrowser/#/R-XTR-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Xenopus tropicalis 29089 R-XTR-75899 https://reactome.org/PathwayBrowser/#/R-XTR-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Xenopus tropicalis 29101 R-BTA-109530 https://reactome.org/PathwayBrowser/#/R-BTA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Bos taurus 29101 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 29101 R-BTA-109539 https://reactome.org/PathwayBrowser/#/R-BTA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Bos taurus 29101 R-BTA-165026 https://reactome.org/PathwayBrowser/#/R-BTA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Bos taurus 29101 R-BTA-189208 https://reactome.org/PathwayBrowser/#/R-BTA-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-194121 https://reactome.org/PathwayBrowser/#/R-BTA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-194187 https://reactome.org/PathwayBrowser/#/R-BTA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-198870 https://reactome.org/PathwayBrowser/#/R-BTA-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-199206 https://reactome.org/PathwayBrowser/#/R-BTA-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Bos taurus 29101 R-BTA-199219 https://reactome.org/PathwayBrowser/#/R-BTA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Bos taurus 29101 R-BTA-200396 https://reactome.org/PathwayBrowser/#/R-BTA-200396 Creatine transport across the plasma membrane IEA Bos taurus 29101 R-BTA-209910 https://reactome.org/PathwayBrowser/#/R-BTA-209910 Iodide is taken up by thyroid epithelial cells IEA Bos taurus 29101 R-BTA-210404 https://reactome.org/PathwayBrowser/#/R-BTA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Bos taurus 29101 R-BTA-212642 https://reactome.org/PathwayBrowser/#/R-BTA-212642 L-Glutamine transport into neurons IEA Bos taurus 29101 R-BTA-2514867 https://reactome.org/PathwayBrowser/#/R-BTA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Bos taurus 29101 R-BTA-2534148 https://reactome.org/PathwayBrowser/#/R-BTA-2534148 Nckx1 exchanges Na+ for Ca2+/K+ TAS Bos taurus 29101 R-BTA-2671885 https://reactome.org/PathwayBrowser/#/R-BTA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Bos taurus 29101 R-BTA-2672334 https://reactome.org/PathwayBrowser/#/R-BTA-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Bos taurus 29101 R-BTA-2730664 https://reactome.org/PathwayBrowser/#/R-BTA-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Bos taurus 29101 R-BTA-2872444 https://reactome.org/PathwayBrowser/#/R-BTA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Bos taurus 29101 R-BTA-2872498 https://reactome.org/PathwayBrowser/#/R-BTA-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Bos taurus 29101 R-BTA-2889070 https://reactome.org/PathwayBrowser/#/R-BTA-2889070 SLC9B2 exchanges Na+ for H+ IEA Bos taurus 29101 R-BTA-3295580 https://reactome.org/PathwayBrowser/#/R-BTA-3295580 TRPM4,5 transport extracellular Na+ to cytosol IEA Bos taurus 29101 R-BTA-351987 https://reactome.org/PathwayBrowser/#/R-BTA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Bos taurus 29101 R-BTA-352029 https://reactome.org/PathwayBrowser/#/R-BTA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Bos taurus 29101 R-BTA-352052 https://reactome.org/PathwayBrowser/#/R-BTA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Bos taurus 29101 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 29101 R-BTA-352108 https://reactome.org/PathwayBrowser/#/R-BTA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Bos taurus 29101 R-BTA-352119 https://reactome.org/PathwayBrowser/#/R-BTA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Bos taurus 29101 R-BTA-352174 https://reactome.org/PathwayBrowser/#/R-BTA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Bos taurus 29101 R-BTA-352182 https://reactome.org/PathwayBrowser/#/R-BTA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Bos taurus 29101 R-BTA-352347 https://reactome.org/PathwayBrowser/#/R-BTA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Bos taurus 29101 R-BTA-352354 https://reactome.org/PathwayBrowser/#/R-BTA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Bos taurus 29101 R-BTA-352364 https://reactome.org/PathwayBrowser/#/R-BTA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Bos taurus 29101 R-BTA-352371 https://reactome.org/PathwayBrowser/#/R-BTA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Bos taurus 29101 R-BTA-352379 https://reactome.org/PathwayBrowser/#/R-BTA-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Bos taurus 29101 R-BTA-352385 https://reactome.org/PathwayBrowser/#/R-BTA-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Bos taurus 29101 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-379393 https://reactome.org/PathwayBrowser/#/R-BTA-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-379415 https://reactome.org/PathwayBrowser/#/R-BTA-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Bos taurus 29101 R-BTA-379426 https://reactome.org/PathwayBrowser/#/R-BTA-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Bos taurus 29101 R-BTA-399711 https://reactome.org/PathwayBrowser/#/R-BTA-399711 Activation of Ca impermeable AMPA receptors IEA Bos taurus 29101 R-BTA-420980 https://reactome.org/PathwayBrowser/#/R-BTA-420980 Activation of Ca permeable AMPA receptors IEA Bos taurus 29101 R-BTA-425483 https://reactome.org/PathwayBrowser/#/R-BTA-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Bos taurus 29101 R-BTA-425577 https://reactome.org/PathwayBrowser/#/R-BTA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Bos taurus 29101 R-BTA-425661 https://reactome.org/PathwayBrowser/#/R-BTA-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Bos taurus 29101 R-BTA-425678 https://reactome.org/PathwayBrowser/#/R-BTA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Bos taurus 29101 R-BTA-425965 https://reactome.org/PathwayBrowser/#/R-BTA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Bos taurus 29101 R-BTA-425983 https://reactome.org/PathwayBrowser/#/R-BTA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Bos taurus 29101 R-BTA-425994 https://reactome.org/PathwayBrowser/#/R-BTA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Bos taurus 29101 R-BTA-426015 https://reactome.org/PathwayBrowser/#/R-BTA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Bos taurus 29101 R-BTA-426086 https://reactome.org/PathwayBrowser/#/R-BTA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-426130 https://reactome.org/PathwayBrowser/#/R-BTA-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-426223 https://reactome.org/PathwayBrowser/#/R-BTA-426223 Cation influx mediated by TRPC3/6/7 IEA Bos taurus 29101 R-BTA-427605 https://reactome.org/PathwayBrowser/#/R-BTA-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-427645 https://reactome.org/PathwayBrowser/#/R-BTA-427645 SLC34A3 cotransports Pi, 2Na+ IEA Bos taurus 29101 R-BTA-427656 https://reactome.org/PathwayBrowser/#/R-BTA-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-428015 https://reactome.org/PathwayBrowser/#/R-BTA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-428609 https://reactome.org/PathwayBrowser/#/R-BTA-428609 Type I Na+-coupled phosphate co-transport IEA Bos taurus 29101 R-BTA-429567 https://reactome.org/PathwayBrowser/#/R-BTA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Bos taurus 29101 R-BTA-429571 https://reactome.org/PathwayBrowser/#/R-BTA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Bos taurus 29101 R-BTA-429581 https://reactome.org/PathwayBrowser/#/R-BTA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-429591 https://reactome.org/PathwayBrowser/#/R-BTA-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-429594 https://reactome.org/PathwayBrowser/#/R-BTA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-429613 https://reactome.org/PathwayBrowser/#/R-BTA-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-433089 https://reactome.org/PathwayBrowser/#/R-BTA-433089 SOAT can transport taurolithocholate-3-sulphate IEA Bos taurus 29101 R-BTA-433099 https://reactome.org/PathwayBrowser/#/R-BTA-433099 NaS2 co-transports sulphate and two sodium ions IEA Bos taurus 29101 R-BTA-433101 https://reactome.org/PathwayBrowser/#/R-BTA-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Bos taurus 29101 R-BTA-433104 https://reactome.org/PathwayBrowser/#/R-BTA-433104 NACT co-transports trivalent citrate and a sodium ion IEA Bos taurus 29101 R-BTA-433114 https://reactome.org/PathwayBrowser/#/R-BTA-433114 NaS1 co-transports sulphate and a sodium ion IEA Bos taurus 29101 R-BTA-433131 https://reactome.org/PathwayBrowser/#/R-BTA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Bos taurus 29101 R-BTA-438037 https://reactome.org/PathwayBrowser/#/R-BTA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Bos taurus 29101 R-BTA-443997 https://reactome.org/PathwayBrowser/#/R-BTA-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-444007 https://reactome.org/PathwayBrowser/#/R-BTA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Bos taurus 29101 R-BTA-444008 https://reactome.org/PathwayBrowser/#/R-BTA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-444100 https://reactome.org/PathwayBrowser/#/R-BTA-444100 PROT mediates L-proline uptake IEA Bos taurus 29101 R-BTA-444120 https://reactome.org/PathwayBrowser/#/R-BTA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-451310 https://reactome.org/PathwayBrowser/#/R-BTA-451310 Activation of Edited Kainate receptors IEA Bos taurus 29101 R-BTA-549241 https://reactome.org/PathwayBrowser/#/R-BTA-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-549297 https://reactome.org/PathwayBrowser/#/R-BTA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-5576895 https://reactome.org/PathwayBrowser/#/R-BTA-5576895 SCNAs:SNCBs transport Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-5626316 https://reactome.org/PathwayBrowser/#/R-BTA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Bos taurus 29101 R-BTA-622325 https://reactome.org/PathwayBrowser/#/R-BTA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 29101 R-BTA-6798528 https://reactome.org/PathwayBrowser/#/R-BTA-6798528 S100A8:S100A9 binds Mn2+ IEA Bos taurus 29101 R-BTA-8865637 https://reactome.org/PathwayBrowser/#/R-BTA-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Bos taurus 29101 R-BTA-8876283 https://reactome.org/PathwayBrowser/#/R-BTA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-8876312 https://reactome.org/PathwayBrowser/#/R-BTA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-8878664 https://reactome.org/PathwayBrowser/#/R-BTA-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Bos taurus 29101 R-BTA-8932955 https://reactome.org/PathwayBrowser/#/R-BTA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-8949688 https://reactome.org/PathwayBrowser/#/R-BTA-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Bos taurus 29101 R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 29101 R-BTA-9648983 https://reactome.org/PathwayBrowser/#/R-BTA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Bos taurus 29101 R-BTA-9751037 https://reactome.org/PathwayBrowser/#/R-BTA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-BTA-975311 https://reactome.org/PathwayBrowser/#/R-BTA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Bos taurus 29101 R-BTA-9754934 https://reactome.org/PathwayBrowser/#/R-BTA-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Bos taurus 29101 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans 29101 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 29101 R-CEL-109539 https://reactome.org/PathwayBrowser/#/R-CEL-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Caenorhabditis elegans 29101 R-CEL-165026 https://reactome.org/PathwayBrowser/#/R-CEL-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Caenorhabditis elegans 29101 R-CEL-194121 https://reactome.org/PathwayBrowser/#/R-CEL-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-194187 https://reactome.org/PathwayBrowser/#/R-CEL-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-198870 https://reactome.org/PathwayBrowser/#/R-CEL-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-209910 https://reactome.org/PathwayBrowser/#/R-CEL-209910 Iodide is taken up by thyroid epithelial cells IEA Caenorhabditis elegans 29101 R-CEL-210404 https://reactome.org/PathwayBrowser/#/R-CEL-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Caenorhabditis elegans 29101 R-CEL-2514867 https://reactome.org/PathwayBrowser/#/R-CEL-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Caenorhabditis elegans 29101 R-CEL-2671885 https://reactome.org/PathwayBrowser/#/R-CEL-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Caenorhabditis elegans 29101 R-CEL-2672334 https://reactome.org/PathwayBrowser/#/R-CEL-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Caenorhabditis elegans 29101 R-CEL-2872444 https://reactome.org/PathwayBrowser/#/R-CEL-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Caenorhabditis elegans 29101 R-CEL-2872498 https://reactome.org/PathwayBrowser/#/R-CEL-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Caenorhabditis elegans 29101 R-CEL-2889070 https://reactome.org/PathwayBrowser/#/R-CEL-2889070 SLC9B2 exchanges Na+ for H+ IEA Caenorhabditis elegans 29101 R-CEL-352347 https://reactome.org/PathwayBrowser/#/R-CEL-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Caenorhabditis elegans 29101 R-CEL-352354 https://reactome.org/PathwayBrowser/#/R-CEL-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Caenorhabditis elegans 29101 R-CEL-352364 https://reactome.org/PathwayBrowser/#/R-CEL-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Caenorhabditis elegans 29101 R-CEL-352371 https://reactome.org/PathwayBrowser/#/R-CEL-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Caenorhabditis elegans 29101 R-CEL-352379 https://reactome.org/PathwayBrowser/#/R-CEL-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Caenorhabditis elegans 29101 R-CEL-352385 https://reactome.org/PathwayBrowser/#/R-CEL-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Caenorhabditis elegans 29101 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-379393 https://reactome.org/PathwayBrowser/#/R-CEL-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-399711 https://reactome.org/PathwayBrowser/#/R-CEL-399711 Activation of Ca impermeable AMPA receptors IEA Caenorhabditis elegans 29101 R-CEL-420980 https://reactome.org/PathwayBrowser/#/R-CEL-420980 Activation of Ca permeable AMPA receptors IEA Caenorhabditis elegans 29101 R-CEL-425483 https://reactome.org/PathwayBrowser/#/R-CEL-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Caenorhabditis elegans 29101 R-CEL-425577 https://reactome.org/PathwayBrowser/#/R-CEL-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Caenorhabditis elegans 29101 R-CEL-425661 https://reactome.org/PathwayBrowser/#/R-CEL-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Caenorhabditis elegans 29101 R-CEL-425678 https://reactome.org/PathwayBrowser/#/R-CEL-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Caenorhabditis elegans 29101 R-CEL-425965 https://reactome.org/PathwayBrowser/#/R-CEL-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Caenorhabditis elegans 29101 R-CEL-425983 https://reactome.org/PathwayBrowser/#/R-CEL-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Caenorhabditis elegans 29101 R-CEL-425994 https://reactome.org/PathwayBrowser/#/R-CEL-425994 Na+/H+ exchanger transport (at cell membrane) IEA Caenorhabditis elegans 29101 R-CEL-426015 https://reactome.org/PathwayBrowser/#/R-CEL-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Caenorhabditis elegans 29101 R-CEL-426086 https://reactome.org/PathwayBrowser/#/R-CEL-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-426130 https://reactome.org/PathwayBrowser/#/R-CEL-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-426223 https://reactome.org/PathwayBrowser/#/R-CEL-426223 Cation influx mediated by TRPC3/6/7 IEA Caenorhabditis elegans 29101 R-CEL-427605 https://reactome.org/PathwayBrowser/#/R-CEL-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-427645 https://reactome.org/PathwayBrowser/#/R-CEL-427645 SLC34A3 cotransports Pi, 2Na+ IEA Caenorhabditis elegans 29101 R-CEL-427656 https://reactome.org/PathwayBrowser/#/R-CEL-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-428015 https://reactome.org/PathwayBrowser/#/R-CEL-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-428609 https://reactome.org/PathwayBrowser/#/R-CEL-428609 Type I Na+-coupled phosphate co-transport IEA Caenorhabditis elegans 29101 R-CEL-429591 https://reactome.org/PathwayBrowser/#/R-CEL-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-429594 https://reactome.org/PathwayBrowser/#/R-CEL-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-433089 https://reactome.org/PathwayBrowser/#/R-CEL-433089 SOAT can transport taurolithocholate-3-sulphate IEA Caenorhabditis elegans 29101 R-CEL-433099 https://reactome.org/PathwayBrowser/#/R-CEL-433099 NaS2 co-transports sulphate and two sodium ions IEA Caenorhabditis elegans 29101 R-CEL-433101 https://reactome.org/PathwayBrowser/#/R-CEL-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Caenorhabditis elegans 29101 R-CEL-433104 https://reactome.org/PathwayBrowser/#/R-CEL-433104 NACT co-transports trivalent citrate and a sodium ion IEA Caenorhabditis elegans 29101 R-CEL-433114 https://reactome.org/PathwayBrowser/#/R-CEL-433114 NaS1 co-transports sulphate and a sodium ion IEA Caenorhabditis elegans 29101 R-CEL-433131 https://reactome.org/PathwayBrowser/#/R-CEL-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Caenorhabditis elegans 29101 R-CEL-438037 https://reactome.org/PathwayBrowser/#/R-CEL-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Caenorhabditis elegans 29101 R-CEL-443997 https://reactome.org/PathwayBrowser/#/R-CEL-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-444007 https://reactome.org/PathwayBrowser/#/R-CEL-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Caenorhabditis elegans 29101 R-CEL-444008 https://reactome.org/PathwayBrowser/#/R-CEL-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-444100 https://reactome.org/PathwayBrowser/#/R-CEL-444100 PROT mediates L-proline uptake IEA Caenorhabditis elegans 29101 R-CEL-444120 https://reactome.org/PathwayBrowser/#/R-CEL-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-549241 https://reactome.org/PathwayBrowser/#/R-CEL-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-549297 https://reactome.org/PathwayBrowser/#/R-CEL-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-622325 https://reactome.org/PathwayBrowser/#/R-CEL-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 29101 R-CEL-8876312 https://reactome.org/PathwayBrowser/#/R-CEL-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-8878664 https://reactome.org/PathwayBrowser/#/R-CEL-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Caenorhabditis elegans 29101 R-CEL-8949688 https://reactome.org/PathwayBrowser/#/R-CEL-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Caenorhabditis elegans 29101 R-CEL-9648983 https://reactome.org/PathwayBrowser/#/R-CEL-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Caenorhabditis elegans 29101 R-CEL-9751037 https://reactome.org/PathwayBrowser/#/R-CEL-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CEL-975311 https://reactome.org/PathwayBrowser/#/R-CEL-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Caenorhabditis elegans 29101 R-CEL-9754934 https://reactome.org/PathwayBrowser/#/R-CEL-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29101 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 29101 R-CFA-165026 https://reactome.org/PathwayBrowser/#/R-CFA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Canis familiaris 29101 R-CFA-189208 https://reactome.org/PathwayBrowser/#/R-CFA-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-194121 https://reactome.org/PathwayBrowser/#/R-CFA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-194187 https://reactome.org/PathwayBrowser/#/R-CFA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-198870 https://reactome.org/PathwayBrowser/#/R-CFA-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-199206 https://reactome.org/PathwayBrowser/#/R-CFA-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Canis familiaris 29101 R-CFA-199219 https://reactome.org/PathwayBrowser/#/R-CFA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Canis familiaris 29101 R-CFA-200396 https://reactome.org/PathwayBrowser/#/R-CFA-200396 Creatine transport across the plasma membrane IEA Canis familiaris 29101 R-CFA-209910 https://reactome.org/PathwayBrowser/#/R-CFA-209910 Iodide is taken up by thyroid epithelial cells IEA Canis familiaris 29101 R-CFA-210404 https://reactome.org/PathwayBrowser/#/R-CFA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Canis familiaris 29101 R-CFA-212642 https://reactome.org/PathwayBrowser/#/R-CFA-212642 L-Glutamine transport into neurons IEA Canis familiaris 29101 R-CFA-2514867 https://reactome.org/PathwayBrowser/#/R-CFA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Canis familiaris 29101 R-CFA-2671885 https://reactome.org/PathwayBrowser/#/R-CFA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Canis familiaris 29101 R-CFA-2672334 https://reactome.org/PathwayBrowser/#/R-CFA-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Canis familiaris 29101 R-CFA-2730664 https://reactome.org/PathwayBrowser/#/R-CFA-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-2872444 https://reactome.org/PathwayBrowser/#/R-CFA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Canis familiaris 29101 R-CFA-2872498 https://reactome.org/PathwayBrowser/#/R-CFA-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Canis familiaris 29101 R-CFA-2889070 https://reactome.org/PathwayBrowser/#/R-CFA-2889070 SLC9B2 exchanges Na+ for H+ IEA Canis familiaris 29101 R-CFA-3295580 https://reactome.org/PathwayBrowser/#/R-CFA-3295580 TRPM4,5 transport extracellular Na+ to cytosol IEA Canis familiaris 29101 R-CFA-351987 https://reactome.org/PathwayBrowser/#/R-CFA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Canis familiaris 29101 R-CFA-352029 https://reactome.org/PathwayBrowser/#/R-CFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Canis familiaris 29101 R-CFA-352052 https://reactome.org/PathwayBrowser/#/R-CFA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 29101 R-CFA-352108 https://reactome.org/PathwayBrowser/#/R-CFA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Canis familiaris 29101 R-CFA-352119 https://reactome.org/PathwayBrowser/#/R-CFA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Canis familiaris 29101 R-CFA-352174 https://reactome.org/PathwayBrowser/#/R-CFA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Canis familiaris 29101 R-CFA-352182 https://reactome.org/PathwayBrowser/#/R-CFA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Canis familiaris 29101 R-CFA-352347 https://reactome.org/PathwayBrowser/#/R-CFA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Canis familiaris 29101 R-CFA-352354 https://reactome.org/PathwayBrowser/#/R-CFA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Canis familiaris 29101 R-CFA-352364 https://reactome.org/PathwayBrowser/#/R-CFA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Canis familiaris 29101 R-CFA-352371 https://reactome.org/PathwayBrowser/#/R-CFA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Canis familiaris 29101 R-CFA-352379 https://reactome.org/PathwayBrowser/#/R-CFA-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Canis familiaris 29101 R-CFA-352385 https://reactome.org/PathwayBrowser/#/R-CFA-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Canis familiaris 29101 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-379393 https://reactome.org/PathwayBrowser/#/R-CFA-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-379426 https://reactome.org/PathwayBrowser/#/R-CFA-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Canis familiaris 29101 R-CFA-399711 https://reactome.org/PathwayBrowser/#/R-CFA-399711 Activation of Ca impermeable AMPA receptors IEA Canis familiaris 29101 R-CFA-420980 https://reactome.org/PathwayBrowser/#/R-CFA-420980 Activation of Ca permeable AMPA receptors IEA Canis familiaris 29101 R-CFA-425483 https://reactome.org/PathwayBrowser/#/R-CFA-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Canis familiaris 29101 R-CFA-425577 https://reactome.org/PathwayBrowser/#/R-CFA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Canis familiaris 29101 R-CFA-425661 https://reactome.org/PathwayBrowser/#/R-CFA-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Canis familiaris 29101 R-CFA-425678 https://reactome.org/PathwayBrowser/#/R-CFA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Canis familiaris 29101 R-CFA-425965 https://reactome.org/PathwayBrowser/#/R-CFA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Canis familiaris 29101 R-CFA-425983 https://reactome.org/PathwayBrowser/#/R-CFA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Canis familiaris 29101 R-CFA-425994 https://reactome.org/PathwayBrowser/#/R-CFA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Canis familiaris 29101 R-CFA-426015 https://reactome.org/PathwayBrowser/#/R-CFA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Canis familiaris 29101 R-CFA-426086 https://reactome.org/PathwayBrowser/#/R-CFA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-426130 https://reactome.org/PathwayBrowser/#/R-CFA-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-426223 https://reactome.org/PathwayBrowser/#/R-CFA-426223 Cation influx mediated by TRPC3/6/7 IEA Canis familiaris 29101 R-CFA-427605 https://reactome.org/PathwayBrowser/#/R-CFA-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-427645 https://reactome.org/PathwayBrowser/#/R-CFA-427645 SLC34A3 cotransports Pi, 2Na+ IEA Canis familiaris 29101 R-CFA-427656 https://reactome.org/PathwayBrowser/#/R-CFA-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-428015 https://reactome.org/PathwayBrowser/#/R-CFA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-428609 https://reactome.org/PathwayBrowser/#/R-CFA-428609 Type I Na+-coupled phosphate co-transport IEA Canis familiaris 29101 R-CFA-429567 https://reactome.org/PathwayBrowser/#/R-CFA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Canis familiaris 29101 R-CFA-429571 https://reactome.org/PathwayBrowser/#/R-CFA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Canis familiaris 29101 R-CFA-429581 https://reactome.org/PathwayBrowser/#/R-CFA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-429591 https://reactome.org/PathwayBrowser/#/R-CFA-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-429594 https://reactome.org/PathwayBrowser/#/R-CFA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-429613 https://reactome.org/PathwayBrowser/#/R-CFA-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-429663 https://reactome.org/PathwayBrowser/#/R-CFA-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-433089 https://reactome.org/PathwayBrowser/#/R-CFA-433089 SOAT can transport taurolithocholate-3-sulphate IEA Canis familiaris 29101 R-CFA-433099 https://reactome.org/PathwayBrowser/#/R-CFA-433099 NaS2 co-transports sulphate and two sodium ions IEA Canis familiaris 29101 R-CFA-433101 https://reactome.org/PathwayBrowser/#/R-CFA-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Canis familiaris 29101 R-CFA-433104 https://reactome.org/PathwayBrowser/#/R-CFA-433104 NACT co-transports trivalent citrate and a sodium ion IEA Canis familiaris 29101 R-CFA-433114 https://reactome.org/PathwayBrowser/#/R-CFA-433114 NaS1 co-transports sulphate and a sodium ion IEA Canis familiaris 29101 R-CFA-433131 https://reactome.org/PathwayBrowser/#/R-CFA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Canis familiaris 29101 R-CFA-438037 https://reactome.org/PathwayBrowser/#/R-CFA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Canis familiaris 29101 R-CFA-443997 https://reactome.org/PathwayBrowser/#/R-CFA-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-444007 https://reactome.org/PathwayBrowser/#/R-CFA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Canis familiaris 29101 R-CFA-444008 https://reactome.org/PathwayBrowser/#/R-CFA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-444100 https://reactome.org/PathwayBrowser/#/R-CFA-444100 PROT mediates L-proline uptake IEA Canis familiaris 29101 R-CFA-444120 https://reactome.org/PathwayBrowser/#/R-CFA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-451310 https://reactome.org/PathwayBrowser/#/R-CFA-451310 Activation of Edited Kainate receptors IEA Canis familiaris 29101 R-CFA-549297 https://reactome.org/PathwayBrowser/#/R-CFA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-5626316 https://reactome.org/PathwayBrowser/#/R-CFA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Canis familiaris 29101 R-CFA-622325 https://reactome.org/PathwayBrowser/#/R-CFA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 29101 R-CFA-6798528 https://reactome.org/PathwayBrowser/#/R-CFA-6798528 S100A8:S100A9 binds Mn2+ IEA Canis familiaris 29101 R-CFA-8865637 https://reactome.org/PathwayBrowser/#/R-CFA-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Canis familiaris 29101 R-CFA-8876283 https://reactome.org/PathwayBrowser/#/R-CFA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-8876312 https://reactome.org/PathwayBrowser/#/R-CFA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-8878664 https://reactome.org/PathwayBrowser/#/R-CFA-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Canis familiaris 29101 R-CFA-8932955 https://reactome.org/PathwayBrowser/#/R-CFA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-8949688 https://reactome.org/PathwayBrowser/#/R-CFA-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Canis familiaris 29101 R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 29101 R-CFA-9648983 https://reactome.org/PathwayBrowser/#/R-CFA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Canis familiaris 29101 R-CFA-9751037 https://reactome.org/PathwayBrowser/#/R-CFA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-CFA-975311 https://reactome.org/PathwayBrowser/#/R-CFA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Canis familiaris 29101 R-CFA-9754934 https://reactome.org/PathwayBrowser/#/R-CFA-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Canis familiaris 29101 R-DDI-2872498 https://reactome.org/PathwayBrowser/#/R-DDI-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Dictyostelium discoideum 29101 R-DDI-425965 https://reactome.org/PathwayBrowser/#/R-DDI-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Dictyostelium discoideum 29101 R-DDI-425983 https://reactome.org/PathwayBrowser/#/R-DDI-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Dictyostelium discoideum 29101 R-DDI-425994 https://reactome.org/PathwayBrowser/#/R-DDI-425994 Na+/H+ exchanger transport (at cell membrane) IEA Dictyostelium discoideum 29101 R-DDI-426015 https://reactome.org/PathwayBrowser/#/R-DDI-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Dictyostelium discoideum 29101 R-DDI-428609 https://reactome.org/PathwayBrowser/#/R-DDI-428609 Type I Na+-coupled phosphate co-transport IEA Dictyostelium discoideum 29101 R-DDI-8865637 https://reactome.org/PathwayBrowser/#/R-DDI-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Dictyostelium discoideum 29101 R-DME-109530 https://reactome.org/PathwayBrowser/#/R-DME-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Drosophila melanogaster 29101 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 29101 R-DME-109539 https://reactome.org/PathwayBrowser/#/R-DME-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Drosophila melanogaster 29101 R-DME-165026 https://reactome.org/PathwayBrowser/#/R-DME-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Drosophila melanogaster 29101 R-DME-194121 https://reactome.org/PathwayBrowser/#/R-DME-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-194187 https://reactome.org/PathwayBrowser/#/R-DME-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-198870 https://reactome.org/PathwayBrowser/#/R-DME-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-209910 https://reactome.org/PathwayBrowser/#/R-DME-209910 Iodide is taken up by thyroid epithelial cells IEA Drosophila melanogaster 29101 R-DME-210404 https://reactome.org/PathwayBrowser/#/R-DME-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Drosophila melanogaster 29101 R-DME-212642 https://reactome.org/PathwayBrowser/#/R-DME-212642 L-Glutamine transport into neurons IEA Drosophila melanogaster 29101 R-DME-2514867 https://reactome.org/PathwayBrowser/#/R-DME-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Drosophila melanogaster 29101 R-DME-2671885 https://reactome.org/PathwayBrowser/#/R-DME-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Drosophila melanogaster 29101 R-DME-2730664 https://reactome.org/PathwayBrowser/#/R-DME-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-2872444 https://reactome.org/PathwayBrowser/#/R-DME-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Drosophila melanogaster 29101 R-DME-2872498 https://reactome.org/PathwayBrowser/#/R-DME-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Drosophila melanogaster 29101 R-DME-2889070 https://reactome.org/PathwayBrowser/#/R-DME-2889070 SLC9B2 exchanges Na+ for H+ IEA Drosophila melanogaster 29101 R-DME-352052 https://reactome.org/PathwayBrowser/#/R-DME-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 29101 R-DME-352108 https://reactome.org/PathwayBrowser/#/R-DME-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 29101 R-DME-352119 https://reactome.org/PathwayBrowser/#/R-DME-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 29101 R-DME-352174 https://reactome.org/PathwayBrowser/#/R-DME-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Drosophila melanogaster 29101 R-DME-352182 https://reactome.org/PathwayBrowser/#/R-DME-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Drosophila melanogaster 29101 R-DME-352347 https://reactome.org/PathwayBrowser/#/R-DME-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Drosophila melanogaster 29101 R-DME-352354 https://reactome.org/PathwayBrowser/#/R-DME-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Drosophila melanogaster 29101 R-DME-352364 https://reactome.org/PathwayBrowser/#/R-DME-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Drosophila melanogaster 29101 R-DME-352371 https://reactome.org/PathwayBrowser/#/R-DME-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Drosophila melanogaster 29101 R-DME-352379 https://reactome.org/PathwayBrowser/#/R-DME-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Drosophila melanogaster 29101 R-DME-352385 https://reactome.org/PathwayBrowser/#/R-DME-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Drosophila melanogaster 29101 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-379393 https://reactome.org/PathwayBrowser/#/R-DME-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-379415 https://reactome.org/PathwayBrowser/#/R-DME-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Drosophila melanogaster 29101 R-DME-379426 https://reactome.org/PathwayBrowser/#/R-DME-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Drosophila melanogaster 29101 R-DME-399711 https://reactome.org/PathwayBrowser/#/R-DME-399711 Activation of Ca impermeable AMPA receptors IEA Drosophila melanogaster 29101 R-DME-420980 https://reactome.org/PathwayBrowser/#/R-DME-420980 Activation of Ca permeable AMPA receptors IEA Drosophila melanogaster 29101 R-DME-425483 https://reactome.org/PathwayBrowser/#/R-DME-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Drosophila melanogaster 29101 R-DME-425577 https://reactome.org/PathwayBrowser/#/R-DME-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Drosophila melanogaster 29101 R-DME-425661 https://reactome.org/PathwayBrowser/#/R-DME-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Drosophila melanogaster 29101 R-DME-425678 https://reactome.org/PathwayBrowser/#/R-DME-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Drosophila melanogaster 29101 R-DME-425965 https://reactome.org/PathwayBrowser/#/R-DME-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Drosophila melanogaster 29101 R-DME-425983 https://reactome.org/PathwayBrowser/#/R-DME-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Drosophila melanogaster 29101 R-DME-425994 https://reactome.org/PathwayBrowser/#/R-DME-425994 Na+/H+ exchanger transport (at cell membrane) IEA Drosophila melanogaster 29101 R-DME-426015 https://reactome.org/PathwayBrowser/#/R-DME-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Drosophila melanogaster 29101 R-DME-426086 https://reactome.org/PathwayBrowser/#/R-DME-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-426130 https://reactome.org/PathwayBrowser/#/R-DME-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-427605 https://reactome.org/PathwayBrowser/#/R-DME-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-428015 https://reactome.org/PathwayBrowser/#/R-DME-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-428609 https://reactome.org/PathwayBrowser/#/R-DME-428609 Type I Na+-coupled phosphate co-transport IEA Drosophila melanogaster 29101 R-DME-429591 https://reactome.org/PathwayBrowser/#/R-DME-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-429594 https://reactome.org/PathwayBrowser/#/R-DME-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-433089 https://reactome.org/PathwayBrowser/#/R-DME-433089 SOAT can transport taurolithocholate-3-sulphate IEA Drosophila melanogaster 29101 R-DME-433099 https://reactome.org/PathwayBrowser/#/R-DME-433099 NaS2 co-transports sulphate and two sodium ions IEA Drosophila melanogaster 29101 R-DME-433101 https://reactome.org/PathwayBrowser/#/R-DME-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Drosophila melanogaster 29101 R-DME-433104 https://reactome.org/PathwayBrowser/#/R-DME-433104 NACT co-transports trivalent citrate and a sodium ion IEA Drosophila melanogaster 29101 R-DME-433114 https://reactome.org/PathwayBrowser/#/R-DME-433114 NaS1 co-transports sulphate and a sodium ion IEA Drosophila melanogaster 29101 R-DME-433131 https://reactome.org/PathwayBrowser/#/R-DME-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Drosophila melanogaster 29101 R-DME-438037 https://reactome.org/PathwayBrowser/#/R-DME-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Drosophila melanogaster 29101 R-DME-443997 https://reactome.org/PathwayBrowser/#/R-DME-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-444007 https://reactome.org/PathwayBrowser/#/R-DME-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Drosophila melanogaster 29101 R-DME-444008 https://reactome.org/PathwayBrowser/#/R-DME-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-444100 https://reactome.org/PathwayBrowser/#/R-DME-444100 PROT mediates L-proline uptake IEA Drosophila melanogaster 29101 R-DME-444120 https://reactome.org/PathwayBrowser/#/R-DME-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-451310 https://reactome.org/PathwayBrowser/#/R-DME-451310 Activation of Edited Kainate receptors IEA Drosophila melanogaster 29101 R-DME-549241 https://reactome.org/PathwayBrowser/#/R-DME-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-549297 https://reactome.org/PathwayBrowser/#/R-DME-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-5626316 https://reactome.org/PathwayBrowser/#/R-DME-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Drosophila melanogaster 29101 R-DME-622325 https://reactome.org/PathwayBrowser/#/R-DME-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 29101 R-DME-8876312 https://reactome.org/PathwayBrowser/#/R-DME-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-8878664 https://reactome.org/PathwayBrowser/#/R-DME-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Drosophila melanogaster 29101 R-DME-8949688 https://reactome.org/PathwayBrowser/#/R-DME-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Drosophila melanogaster 29101 R-DME-9751037 https://reactome.org/PathwayBrowser/#/R-DME-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DME-9754934 https://reactome.org/PathwayBrowser/#/R-DME-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29101 R-DRE-165026 https://reactome.org/PathwayBrowser/#/R-DRE-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Danio rerio 29101 R-DRE-189208 https://reactome.org/PathwayBrowser/#/R-DRE-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-194121 https://reactome.org/PathwayBrowser/#/R-DRE-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-194187 https://reactome.org/PathwayBrowser/#/R-DRE-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-199206 https://reactome.org/PathwayBrowser/#/R-DRE-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Danio rerio 29101 R-DRE-199219 https://reactome.org/PathwayBrowser/#/R-DRE-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Danio rerio 29101 R-DRE-209910 https://reactome.org/PathwayBrowser/#/R-DRE-209910 Iodide is taken up by thyroid epithelial cells IEA Danio rerio 29101 R-DRE-210404 https://reactome.org/PathwayBrowser/#/R-DRE-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Danio rerio 29101 R-DRE-212642 https://reactome.org/PathwayBrowser/#/R-DRE-212642 L-Glutamine transport into neurons IEA Danio rerio 29101 R-DRE-2671885 https://reactome.org/PathwayBrowser/#/R-DRE-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Danio rerio 29101 R-DRE-3295580 https://reactome.org/PathwayBrowser/#/R-DRE-3295580 TRPM4,5 transport extracellular Na+ to cytosol IEA Danio rerio 29101 R-DRE-351987 https://reactome.org/PathwayBrowser/#/R-DRE-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Danio rerio 29101 R-DRE-352029 https://reactome.org/PathwayBrowser/#/R-DRE-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Danio rerio 29101 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 29101 R-DRE-352108 https://reactome.org/PathwayBrowser/#/R-DRE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Danio rerio 29101 R-DRE-352182 https://reactome.org/PathwayBrowser/#/R-DRE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Danio rerio 29101 R-DRE-352347 https://reactome.org/PathwayBrowser/#/R-DRE-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Danio rerio 29101 R-DRE-352354 https://reactome.org/PathwayBrowser/#/R-DRE-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Danio rerio 29101 R-DRE-352364 https://reactome.org/PathwayBrowser/#/R-DRE-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Danio rerio 29101 R-DRE-352371 https://reactome.org/PathwayBrowser/#/R-DRE-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Danio rerio 29101 R-DRE-352379 https://reactome.org/PathwayBrowser/#/R-DRE-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Danio rerio 29101 R-DRE-352385 https://reactome.org/PathwayBrowser/#/R-DRE-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Danio rerio 29101 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-379393 https://reactome.org/PathwayBrowser/#/R-DRE-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-379415 https://reactome.org/PathwayBrowser/#/R-DRE-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Danio rerio 29101 R-DRE-379426 https://reactome.org/PathwayBrowser/#/R-DRE-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Danio rerio 29101 R-DRE-420980 https://reactome.org/PathwayBrowser/#/R-DRE-420980 Activation of Ca permeable AMPA receptors IEA Danio rerio 29101 R-DRE-425661 https://reactome.org/PathwayBrowser/#/R-DRE-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Danio rerio 29101 R-DRE-425983 https://reactome.org/PathwayBrowser/#/R-DRE-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Danio rerio 29101 R-DRE-425994 https://reactome.org/PathwayBrowser/#/R-DRE-425994 Na+/H+ exchanger transport (at cell membrane) IEA Danio rerio 29101 R-DRE-426015 https://reactome.org/PathwayBrowser/#/R-DRE-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Danio rerio 29101 R-DRE-426086 https://reactome.org/PathwayBrowser/#/R-DRE-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-426223 https://reactome.org/PathwayBrowser/#/R-DRE-426223 Cation influx mediated by TRPC3/6/7 IEA Danio rerio 29101 R-DRE-427605 https://reactome.org/PathwayBrowser/#/R-DRE-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-427656 https://reactome.org/PathwayBrowser/#/R-DRE-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-428015 https://reactome.org/PathwayBrowser/#/R-DRE-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-429567 https://reactome.org/PathwayBrowser/#/R-DRE-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Danio rerio 29101 R-DRE-429571 https://reactome.org/PathwayBrowser/#/R-DRE-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Danio rerio 29101 R-DRE-429581 https://reactome.org/PathwayBrowser/#/R-DRE-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-429591 https://reactome.org/PathwayBrowser/#/R-DRE-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-429613 https://reactome.org/PathwayBrowser/#/R-DRE-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-433101 https://reactome.org/PathwayBrowser/#/R-DRE-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Danio rerio 29101 R-DRE-433114 https://reactome.org/PathwayBrowser/#/R-DRE-433114 NaS1 co-transports sulphate and a sodium ion IEA Danio rerio 29101 R-DRE-433131 https://reactome.org/PathwayBrowser/#/R-DRE-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Danio rerio 29101 R-DRE-443997 https://reactome.org/PathwayBrowser/#/R-DRE-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-444007 https://reactome.org/PathwayBrowser/#/R-DRE-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Danio rerio 29101 R-DRE-444008 https://reactome.org/PathwayBrowser/#/R-DRE-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-444120 https://reactome.org/PathwayBrowser/#/R-DRE-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-549241 https://reactome.org/PathwayBrowser/#/R-DRE-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-549297 https://reactome.org/PathwayBrowser/#/R-DRE-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-6798528 https://reactome.org/PathwayBrowser/#/R-DRE-6798528 S100A8:S100A9 binds Mn2+ IEA Danio rerio 29101 R-DRE-8865637 https://reactome.org/PathwayBrowser/#/R-DRE-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Danio rerio 29101 R-DRE-8876312 https://reactome.org/PathwayBrowser/#/R-DRE-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-8932955 https://reactome.org/PathwayBrowser/#/R-DRE-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Danio rerio 29101 R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 29101 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 29101 R-GGA-109539 https://reactome.org/PathwayBrowser/#/R-GGA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Gallus gallus 29101 R-GGA-165026 https://reactome.org/PathwayBrowser/#/R-GGA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Gallus gallus 29101 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-198870 https://reactome.org/PathwayBrowser/#/R-GGA-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-199206 https://reactome.org/PathwayBrowser/#/R-GGA-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Gallus gallus 29101 R-GGA-199219 https://reactome.org/PathwayBrowser/#/R-GGA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Gallus gallus 29101 R-GGA-209910 https://reactome.org/PathwayBrowser/#/R-GGA-209910 Iodide is taken up by thyroid epithelial cells IEA Gallus gallus 29101 R-GGA-210404 https://reactome.org/PathwayBrowser/#/R-GGA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Gallus gallus 29101 R-GGA-212642 https://reactome.org/PathwayBrowser/#/R-GGA-212642 L-Glutamine transport into neurons IEA Gallus gallus 29101 R-GGA-2514867 https://reactome.org/PathwayBrowser/#/R-GGA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Gallus gallus 29101 R-GGA-2671885 https://reactome.org/PathwayBrowser/#/R-GGA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Gallus gallus 29101 R-GGA-2672334 https://reactome.org/PathwayBrowser/#/R-GGA-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Gallus gallus 29101 R-GGA-2730664 https://reactome.org/PathwayBrowser/#/R-GGA-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-2872444 https://reactome.org/PathwayBrowser/#/R-GGA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Gallus gallus 29101 R-GGA-2889070 https://reactome.org/PathwayBrowser/#/R-GGA-2889070 SLC9B2 exchanges Na+ for H+ IEA Gallus gallus 29101 R-GGA-3295580 https://reactome.org/PathwayBrowser/#/R-GGA-3295580 TRPM4,5 transport extracellular Na+ to cytosol IEA Gallus gallus 29101 R-GGA-351987 https://reactome.org/PathwayBrowser/#/R-GGA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Gallus gallus 29101 R-GGA-352029 https://reactome.org/PathwayBrowser/#/R-GGA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Gallus gallus 29101 R-GGA-352052 https://reactome.org/PathwayBrowser/#/R-GGA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 29101 R-GGA-352108 https://reactome.org/PathwayBrowser/#/R-GGA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Gallus gallus 29101 R-GGA-352119 https://reactome.org/PathwayBrowser/#/R-GGA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Gallus gallus 29101 R-GGA-352174 https://reactome.org/PathwayBrowser/#/R-GGA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Gallus gallus 29101 R-GGA-352347 https://reactome.org/PathwayBrowser/#/R-GGA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Gallus gallus 29101 R-GGA-352354 https://reactome.org/PathwayBrowser/#/R-GGA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Gallus gallus 29101 R-GGA-352364 https://reactome.org/PathwayBrowser/#/R-GGA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Gallus gallus 29101 R-GGA-352371 https://reactome.org/PathwayBrowser/#/R-GGA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Gallus gallus 29101 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-399711 https://reactome.org/PathwayBrowser/#/R-GGA-399711 Activation of Ca impermeable AMPA receptors IEA Gallus gallus 29101 R-GGA-420980 https://reactome.org/PathwayBrowser/#/R-GGA-420980 Activation of Ca permeable AMPA receptors IEA Gallus gallus 29101 R-GGA-425483 https://reactome.org/PathwayBrowser/#/R-GGA-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Gallus gallus 29101 R-GGA-425577 https://reactome.org/PathwayBrowser/#/R-GGA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Gallus gallus 29101 R-GGA-425661 https://reactome.org/PathwayBrowser/#/R-GGA-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Gallus gallus 29101 R-GGA-425678 https://reactome.org/PathwayBrowser/#/R-GGA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Gallus gallus 29101 R-GGA-425965 https://reactome.org/PathwayBrowser/#/R-GGA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Gallus gallus 29101 R-GGA-425983 https://reactome.org/PathwayBrowser/#/R-GGA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Gallus gallus 29101 R-GGA-425994 https://reactome.org/PathwayBrowser/#/R-GGA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Gallus gallus 29101 R-GGA-426015 https://reactome.org/PathwayBrowser/#/R-GGA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Gallus gallus 29101 R-GGA-426086 https://reactome.org/PathwayBrowser/#/R-GGA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-426223 https://reactome.org/PathwayBrowser/#/R-GGA-426223 Cation influx mediated by TRPC3/6/7 IEA Gallus gallus 29101 R-GGA-427605 https://reactome.org/PathwayBrowser/#/R-GGA-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-427656 https://reactome.org/PathwayBrowser/#/R-GGA-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-428015 https://reactome.org/PathwayBrowser/#/R-GGA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-429567 https://reactome.org/PathwayBrowser/#/R-GGA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Gallus gallus 29101 R-GGA-429571 https://reactome.org/PathwayBrowser/#/R-GGA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Gallus gallus 29101 R-GGA-429581 https://reactome.org/PathwayBrowser/#/R-GGA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-429591 https://reactome.org/PathwayBrowser/#/R-GGA-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-429594 https://reactome.org/PathwayBrowser/#/R-GGA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-433099 https://reactome.org/PathwayBrowser/#/R-GGA-433099 NaS2 co-transports sulphate and two sodium ions IEA Gallus gallus 29101 R-GGA-433101 https://reactome.org/PathwayBrowser/#/R-GGA-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Gallus gallus 29101 R-GGA-433104 https://reactome.org/PathwayBrowser/#/R-GGA-433104 NACT co-transports trivalent citrate and a sodium ion IEA Gallus gallus 29101 R-GGA-433114 https://reactome.org/PathwayBrowser/#/R-GGA-433114 NaS1 co-transports sulphate and a sodium ion IEA Gallus gallus 29101 R-GGA-433131 https://reactome.org/PathwayBrowser/#/R-GGA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Gallus gallus 29101 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus 29101 R-GGA-443997 https://reactome.org/PathwayBrowser/#/R-GGA-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-444007 https://reactome.org/PathwayBrowser/#/R-GGA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Gallus gallus 29101 R-GGA-444008 https://reactome.org/PathwayBrowser/#/R-GGA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-444100 https://reactome.org/PathwayBrowser/#/R-GGA-444100 PROT mediates L-proline uptake IEA Gallus gallus 29101 R-GGA-444120 https://reactome.org/PathwayBrowser/#/R-GGA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-451310 https://reactome.org/PathwayBrowser/#/R-GGA-451310 Activation of Edited Kainate receptors IEA Gallus gallus 29101 R-GGA-549241 https://reactome.org/PathwayBrowser/#/R-GGA-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-549297 https://reactome.org/PathwayBrowser/#/R-GGA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-5626316 https://reactome.org/PathwayBrowser/#/R-GGA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Gallus gallus 29101 R-GGA-622325 https://reactome.org/PathwayBrowser/#/R-GGA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 29101 R-GGA-6798528 https://reactome.org/PathwayBrowser/#/R-GGA-6798528 S100A8:S100A9 binds Mn2+ IEA Gallus gallus 29101 R-GGA-8865637 https://reactome.org/PathwayBrowser/#/R-GGA-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Gallus gallus 29101 R-GGA-8876283 https://reactome.org/PathwayBrowser/#/R-GGA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-8876312 https://reactome.org/PathwayBrowser/#/R-GGA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-8878664 https://reactome.org/PathwayBrowser/#/R-GGA-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Gallus gallus 29101 R-GGA-8932955 https://reactome.org/PathwayBrowser/#/R-GGA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 29101 R-GGA-9751037 https://reactome.org/PathwayBrowser/#/R-GGA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-GGA-9754934 https://reactome.org/PathwayBrowser/#/R-GGA-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Gallus gallus 29101 R-HSA-109530 https://reactome.org/PathwayBrowser/#/R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 TAS Homo sapiens 29101 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 29101 R-HSA-109539 https://reactome.org/PathwayBrowser/#/R-HSA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 TAS Homo sapiens 29101 R-HSA-165026 https://reactome.org/PathwayBrowser/#/R-HSA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol TAS Homo sapiens 29101 R-HSA-189208 https://reactome.org/PathwayBrowser/#/R-HSA-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-194121 https://reactome.org/PathwayBrowser/#/R-HSA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-194187 https://reactome.org/PathwayBrowser/#/R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-198870 https://reactome.org/PathwayBrowser/#/R-HSA-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-199206 https://reactome.org/PathwayBrowser/#/R-HSA-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol TAS Homo sapiens 29101 R-HSA-199219 https://reactome.org/PathwayBrowser/#/R-HSA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol TAS Homo sapiens 29101 R-HSA-200396 https://reactome.org/PathwayBrowser/#/R-HSA-200396 Creatine transport across the plasma membrane TAS Homo sapiens 29101 R-HSA-209910 https://reactome.org/PathwayBrowser/#/R-HSA-209910 Iodide is taken up by thyroid epithelial cells TAS Homo sapiens 29101 R-HSA-210404 https://reactome.org/PathwayBrowser/#/R-HSA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ TAS Homo sapiens 29101 R-HSA-212642 https://reactome.org/PathwayBrowser/#/R-HSA-212642 L-Glutamine transport into neurons TAS Homo sapiens 29101 R-HSA-2514867 https://reactome.org/PathwayBrowser/#/R-HSA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment TAS Homo sapiens 29101 R-HSA-2514891 https://reactome.org/PathwayBrowser/#/R-HSA-2514891 SLC24A1 exchanges 4Na+ for Ca2+, K+ IEA Homo sapiens 29101 R-HSA-2671885 https://reactome.org/PathwayBrowser/#/R-HSA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol TAS Homo sapiens 29101 R-HSA-2672334 https://reactome.org/PathwayBrowser/#/R-HSA-2672334 SCNN channels transport extracellular Na+ to cytosol TAS Homo sapiens 29101 R-HSA-2730664 https://reactome.org/PathwayBrowser/#/R-HSA-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-2872444 https://reactome.org/PathwayBrowser/#/R-HSA-2872444 SLC9B1/C2 exchange Na+ for H+ TAS Homo sapiens 29101 R-HSA-2872463 https://reactome.org/PathwayBrowser/#/R-HSA-2872463 SLC9C1 exchanges Na+ for H+ IEA Homo sapiens 29101 R-HSA-2872498 https://reactome.org/PathwayBrowser/#/R-HSA-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol TAS Homo sapiens 29101 R-HSA-2889070 https://reactome.org/PathwayBrowser/#/R-HSA-2889070 SLC9B2 exchanges Na+ for H+ TAS Homo sapiens 29101 R-HSA-3295580 https://reactome.org/PathwayBrowser/#/R-HSA-3295580 TRPM4,5 transport extracellular Na+ to cytosol TAS Homo sapiens 29101 R-HSA-351987 https://reactome.org/PathwayBrowser/#/R-HSA-351987 SLC6A6-mediated uptake of taurine and beta-alanine TAS Homo sapiens 29101 R-HSA-352029 https://reactome.org/PathwayBrowser/#/R-HSA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine TAS Homo sapiens 29101 R-HSA-352052 https://reactome.org/PathwayBrowser/#/R-HSA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 29101 R-HSA-352108 https://reactome.org/PathwayBrowser/#/R-HSA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids TAS Homo sapiens 29101 R-HSA-352119 https://reactome.org/PathwayBrowser/#/R-HSA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids TAS Homo sapiens 29101 R-HSA-352174 https://reactome.org/PathwayBrowser/#/R-HSA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine TAS Homo sapiens 29101 R-HSA-352182 https://reactome.org/PathwayBrowser/#/R-HSA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine TAS Homo sapiens 29101 R-HSA-352347 https://reactome.org/PathwayBrowser/#/R-HSA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine TAS Homo sapiens 29101 R-HSA-352354 https://reactome.org/PathwayBrowser/#/R-HSA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine TAS Homo sapiens 29101 R-HSA-352364 https://reactome.org/PathwayBrowser/#/R-HSA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine TAS Homo sapiens 29101 R-HSA-352371 https://reactome.org/PathwayBrowser/#/R-HSA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine TAS Homo sapiens 29101 R-HSA-352379 https://reactome.org/PathwayBrowser/#/R-HSA-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane TAS Homo sapiens 29101 R-HSA-352385 https://reactome.org/PathwayBrowser/#/R-HSA-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane TAS Homo sapiens 29101 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-379393 https://reactome.org/PathwayBrowser/#/R-HSA-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-379415 https://reactome.org/PathwayBrowser/#/R-HSA-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane TAS Homo sapiens 29101 R-HSA-379426 https://reactome.org/PathwayBrowser/#/R-HSA-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine TAS Homo sapiens 29101 R-HSA-380620 https://reactome.org/PathwayBrowser/#/R-HSA-380620 Reuptake of serotonin from the synapse TAS Homo sapiens 29101 R-HSA-399711 https://reactome.org/PathwayBrowser/#/R-HSA-399711 Activation of Ca impermeable AMPA receptors TAS Homo sapiens 29101 R-HSA-420980 https://reactome.org/PathwayBrowser/#/R-HSA-420980 Activation of Ca permeable AMPA receptors TAS Homo sapiens 29101 R-HSA-425483 https://reactome.org/PathwayBrowser/#/R-HSA-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- TAS Homo sapiens 29101 R-HSA-425577 https://reactome.org/PathwayBrowser/#/R-HSA-425577 Na+-driven Cl-/HCO3- exchanger transport TAS Homo sapiens 29101 R-HSA-425661 https://reactome.org/PathwayBrowser/#/R-HSA-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ TAS Homo sapiens 29101 R-HSA-425678 https://reactome.org/PathwayBrowser/#/R-HSA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ TAS Homo sapiens 29101 R-HSA-425965 https://reactome.org/PathwayBrowser/#/R-HSA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane TAS Homo sapiens 29101 R-HSA-425983 https://reactome.org/PathwayBrowser/#/R-HSA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane TAS Homo sapiens 29101 R-HSA-425994 https://reactome.org/PathwayBrowser/#/R-HSA-425994 Na+/H+ exchanger transport (at cell membrane) TAS Homo sapiens 29101 R-HSA-426015 https://reactome.org/PathwayBrowser/#/R-HSA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) TAS Homo sapiens 29101 R-HSA-426086 https://reactome.org/PathwayBrowser/#/R-HSA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-426130 https://reactome.org/PathwayBrowser/#/R-HSA-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-426223 https://reactome.org/PathwayBrowser/#/R-HSA-426223 Cation influx mediated by TRPC3/6/7 TAS Homo sapiens 29101 R-HSA-427605 https://reactome.org/PathwayBrowser/#/R-HSA-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-427645 https://reactome.org/PathwayBrowser/#/R-HSA-427645 SLC34A3 cotransports Pi, 2Na+ TAS Homo sapiens 29101 R-HSA-427656 https://reactome.org/PathwayBrowser/#/R-HSA-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-428015 https://reactome.org/PathwayBrowser/#/R-HSA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-428609 https://reactome.org/PathwayBrowser/#/R-HSA-428609 Type I Na+-coupled phosphate co-transport TAS Homo sapiens 29101 R-HSA-429567 https://reactome.org/PathwayBrowser/#/R-HSA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 TAS Homo sapiens 29101 R-HSA-429571 https://reactome.org/PathwayBrowser/#/R-HSA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 TAS Homo sapiens 29101 R-HSA-429581 https://reactome.org/PathwayBrowser/#/R-HSA-429581 SLC5A6 transports vitamins from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-429591 https://reactome.org/PathwayBrowser/#/R-HSA-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-429594 https://reactome.org/PathwayBrowser/#/R-HSA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-429613 https://reactome.org/PathwayBrowser/#/R-HSA-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-429663 https://reactome.org/PathwayBrowser/#/R-HSA-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-432162 https://reactome.org/PathwayBrowser/#/R-HSA-432162 Unblocking of GRIN1:GRIN2 NMDA receptors IEA Homo sapiens 29101 R-HSA-433089 https://reactome.org/PathwayBrowser/#/R-HSA-433089 SOAT can transport taurolithocholate-3-sulphate TAS Homo sapiens 29101 R-HSA-433099 https://reactome.org/PathwayBrowser/#/R-HSA-433099 NaS2 co-transports sulphate and two sodium ions TAS Homo sapiens 29101 R-HSA-433101 https://reactome.org/PathwayBrowser/#/R-HSA-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion TAS Homo sapiens 29101 R-HSA-433104 https://reactome.org/PathwayBrowser/#/R-HSA-433104 NACT co-transports trivalent citrate and a sodium ion TAS Homo sapiens 29101 R-HSA-433114 https://reactome.org/PathwayBrowser/#/R-HSA-433114 NaS1 co-transports sulphate and a sodium ion TAS Homo sapiens 29101 R-HSA-433131 https://reactome.org/PathwayBrowser/#/R-HSA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion TAS Homo sapiens 29101 R-HSA-438037 https://reactome.org/PathwayBrowser/#/R-HSA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors TAS Homo sapiens 29101 R-HSA-443997 https://reactome.org/PathwayBrowser/#/R-HSA-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-444007 https://reactome.org/PathwayBrowser/#/R-HSA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport TAS Homo sapiens 29101 R-HSA-444008 https://reactome.org/PathwayBrowser/#/R-HSA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-444100 https://reactome.org/PathwayBrowser/#/R-HSA-444100 PROT mediates L-proline uptake TAS Homo sapiens 29101 R-HSA-444120 https://reactome.org/PathwayBrowser/#/R-HSA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-451310 https://reactome.org/PathwayBrowser/#/R-HSA-451310 Activation of Edited Kainate receptors TAS Homo sapiens 29101 R-HSA-549241 https://reactome.org/PathwayBrowser/#/R-HSA-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-549297 https://reactome.org/PathwayBrowser/#/R-HSA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5576895 https://reactome.org/PathwayBrowser/#/R-HSA-5576895 SCNAs:SNCBs transport Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5623588 https://reactome.org/PathwayBrowser/#/R-HSA-5623588 Defective SLC12A1 does not cotransport Na+, K+, 2Cl- from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5623705 https://reactome.org/PathwayBrowser/#/R-HSA-5623705 Defective SLC12A3 does not cotransport Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5625015 https://reactome.org/PathwayBrowser/#/R-HSA-5625015 Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5625029 https://reactome.org/PathwayBrowser/#/R-HSA-5625029 SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5625123 https://reactome.org/PathwayBrowser/#/R-HSA-5625123 Defective SLC20A2 does not cotransport Pi, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5625674 https://reactome.org/PathwayBrowser/#/R-HSA-5625674 Defective SLC22A5 does not cotransport CAR, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5625841 https://reactome.org/PathwayBrowser/#/R-HSA-5625841 Defective SLC24A1 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ TAS Homo sapiens 29101 R-HSA-5626270 https://reactome.org/PathwayBrowser/#/R-HSA-5626270 Defective SLC24A4 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ TAS Homo sapiens 29101 R-HSA-5626316 https://reactome.org/PathwayBrowser/#/R-HSA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ TAS Homo sapiens 29101 R-HSA-5626356 https://reactome.org/PathwayBrowser/#/R-HSA-5626356 Defective SLC24A5 does not exchange cytosolic 4Na+ for Golgi luminal Ca2+, K+ TAS Homo sapiens 29101 R-HSA-5651685 https://reactome.org/PathwayBrowser/#/R-HSA-5651685 Defective SLC34A1 does not cotransport Pi, 3Na+ TAS Homo sapiens 29101 R-HSA-5651697 https://reactome.org/PathwayBrowser/#/R-HSA-5651697 Defective SLC34A2 does not cotransport Pi, 3Na+ TAS Homo sapiens 29101 R-HSA-5651971 https://reactome.org/PathwayBrowser/#/R-HSA-5651971 Defective SLC34A3 does not cotransport Pi, 2Na+ TAS Homo sapiens 29101 R-HSA-5656219 https://reactome.org/PathwayBrowser/#/R-HSA-5656219 Defective SLC4A4 does not cotransport Na+ with 3HCO3- TAS Homo sapiens 29101 R-HSA-5656356 https://reactome.org/PathwayBrowser/#/R-HSA-5656356 Defective SLC5A1 does not cotransport Glc and Na+ TAS Homo sapiens 29101 R-HSA-5658163 https://reactome.org/PathwayBrowser/#/R-HSA-5658163 Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5658195 https://reactome.org/PathwayBrowser/#/R-HSA-5658195 Defective SLC5A5 does not cotransport Na+ with I- from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5658483 https://reactome.org/PathwayBrowser/#/R-HSA-5658483 Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5659764 https://reactome.org/PathwayBrowser/#/R-HSA-5659764 Defective SLC6A2 does not cotransport NAd, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5660694 https://reactome.org/PathwayBrowser/#/R-HSA-5660694 Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol TAS Homo sapiens 29101 R-HSA-5660706 https://reactome.org/PathwayBrowser/#/R-HSA-5660706 Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5660840 https://reactome.org/PathwayBrowser/#/R-HSA-5660840 Defective SLC6A5 does not cotransport Gly, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-5660910 https://reactome.org/PathwayBrowser/#/R-HSA-5660910 Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane TAS Homo sapiens 29101 R-HSA-5661039 https://reactome.org/PathwayBrowser/#/R-HSA-5661039 Defective SLC9A6 does not exchange Na+ for H+ across the early endosome membrane TAS Homo sapiens 29101 R-HSA-5661086 https://reactome.org/PathwayBrowser/#/R-HSA-5661086 Defective SLC9A9 does not exchange Na+ for H+ across the late endosome membrane TAS Homo sapiens 29101 R-HSA-5687585 https://reactome.org/PathwayBrowser/#/R-HSA-5687585 Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-622325 https://reactome.org/PathwayBrowser/#/R-HSA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 29101 R-HSA-6798528 https://reactome.org/PathwayBrowser/#/R-HSA-6798528 S100A8:S100A9 binds Mn2+ TAS Homo sapiens 29101 R-HSA-8865637 https://reactome.org/PathwayBrowser/#/R-HSA-8865637 MFSD2A transports LPC from extracellular region to plasma membrane TAS Homo sapiens 29101 R-HSA-8876283 https://reactome.org/PathwayBrowser/#/R-HSA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-8876312 https://reactome.org/PathwayBrowser/#/R-HSA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-8878664 https://reactome.org/PathwayBrowser/#/R-HSA-8878664 SLC4A4 cotransports Na+ with 3HCO3- TAS Homo sapiens 29101 R-HSA-8932955 https://reactome.org/PathwayBrowser/#/R-HSA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-8949688 https://reactome.org/PathwayBrowser/#/R-HSA-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) TAS Homo sapiens 29101 R-HSA-8949703 https://reactome.org/PathwayBrowser/#/R-HSA-8949703 SLC8A3 (NCX3) exchanges sodium (cytosol) for calcium (mitochondrial intermembrane space) IEA Homo sapiens 29101 R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 29101 R-HSA-9648983 https://reactome.org/PathwayBrowser/#/R-HSA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ TAS Homo sapiens 29101 R-HSA-9712190 https://reactome.org/PathwayBrowser/#/R-HSA-9712190 cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol IEA Homo sapiens 29101 R-HSA-9717374 https://reactome.org/PathwayBrowser/#/R-HSA-9717374 SCN3A:SCN2B,4B transports Na+ from the extracellular region to the cytosol IEA Homo sapiens 29101 R-HSA-9717382 https://reactome.org/PathwayBrowser/#/R-HSA-9717382 SCN9A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol IEA Homo sapiens 29101 R-HSA-9717383 https://reactome.org/PathwayBrowser/#/R-HSA-9717383 TRPM4 transports Na+ from the extracellular region to the cytosol IEA Homo sapiens 29101 R-HSA-9717392 https://reactome.org/PathwayBrowser/#/R-HSA-9717392 CALHM1:CALHM3 transports ATP from the cytosol to the extracellular region IEA Homo sapiens 29101 R-HSA-9717395 https://reactome.org/PathwayBrowser/#/R-HSA-9717395 TRPM5 transports Na+ from the extracellular region to the cytosol IEA Homo sapiens 29101 R-HSA-9717396 https://reactome.org/PathwayBrowser/#/R-HSA-9717396 SCN2A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol IEA Homo sapiens 29101 R-HSA-9751037 https://reactome.org/PathwayBrowser/#/R-HSA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-HSA-975311 https://reactome.org/PathwayBrowser/#/R-HSA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ TAS Homo sapiens 29101 R-HSA-9754934 https://reactome.org/PathwayBrowser/#/R-HSA-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol TAS Homo sapiens 29101 R-MMU-109530 https://reactome.org/PathwayBrowser/#/R-MMU-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Mus musculus 29101 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 29101 R-MMU-109539 https://reactome.org/PathwayBrowser/#/R-MMU-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Mus musculus 29101 R-MMU-165026 https://reactome.org/PathwayBrowser/#/R-MMU-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Mus musculus 29101 R-MMU-189208 https://reactome.org/PathwayBrowser/#/R-MMU-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-194121 https://reactome.org/PathwayBrowser/#/R-MMU-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-194187 https://reactome.org/PathwayBrowser/#/R-MMU-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-198870 https://reactome.org/PathwayBrowser/#/R-MMU-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-199206 https://reactome.org/PathwayBrowser/#/R-MMU-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Mus musculus 29101 R-MMU-199219 https://reactome.org/PathwayBrowser/#/R-MMU-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Mus musculus 29101 R-MMU-200396 https://reactome.org/PathwayBrowser/#/R-MMU-200396 Creatine transport across the plasma membrane IEA Mus musculus 29101 R-MMU-209910 https://reactome.org/PathwayBrowser/#/R-MMU-209910 Iodide is taken up by thyroid epithelial cells IEA Mus musculus 29101 R-MMU-210404 https://reactome.org/PathwayBrowser/#/R-MMU-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Mus musculus 29101 R-MMU-212642 https://reactome.org/PathwayBrowser/#/R-MMU-212642 L-Glutamine transport into neurons IEA Mus musculus 29101 R-MMU-2514867 https://reactome.org/PathwayBrowser/#/R-MMU-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Mus musculus 29101 R-MMU-2671885 https://reactome.org/PathwayBrowser/#/R-MMU-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Mus musculus 29101 R-MMU-2672334 https://reactome.org/PathwayBrowser/#/R-MMU-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Mus musculus 29101 R-MMU-2730664 https://reactome.org/PathwayBrowser/#/R-MMU-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Mus musculus 29101 R-MMU-2872444 https://reactome.org/PathwayBrowser/#/R-MMU-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Mus musculus 29101 R-MMU-2872452 https://reactome.org/PathwayBrowser/#/R-MMU-2872452 Slc9c1 exchanges Na+ for H+ TAS Mus musculus 29101 R-MMU-2872498 https://reactome.org/PathwayBrowser/#/R-MMU-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Mus musculus 29101 R-MMU-2889070 https://reactome.org/PathwayBrowser/#/R-MMU-2889070 SLC9B2 exchanges Na+ for H+ IEA Mus musculus 29101 R-MMU-3295580 https://reactome.org/PathwayBrowser/#/R-MMU-3295580 TRPM4,5 transport extracellular Na+ to cytosol IEA Mus musculus 29101 R-MMU-351987 https://reactome.org/PathwayBrowser/#/R-MMU-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Mus musculus 29101 R-MMU-352029 https://reactome.org/PathwayBrowser/#/R-MMU-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Mus musculus 29101 R-MMU-352052 https://reactome.org/PathwayBrowser/#/R-MMU-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Mus musculus 29101 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 29101 R-MMU-352108 https://reactome.org/PathwayBrowser/#/R-MMU-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Mus musculus 29101 R-MMU-352119 https://reactome.org/PathwayBrowser/#/R-MMU-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Mus musculus 29101 R-MMU-352174 https://reactome.org/PathwayBrowser/#/R-MMU-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Mus musculus 29101 R-MMU-352182 https://reactome.org/PathwayBrowser/#/R-MMU-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Mus musculus 29101 R-MMU-352347 https://reactome.org/PathwayBrowser/#/R-MMU-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Mus musculus 29101 R-MMU-352354 https://reactome.org/PathwayBrowser/#/R-MMU-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Mus musculus 29101 R-MMU-352364 https://reactome.org/PathwayBrowser/#/R-MMU-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Mus musculus 29101 R-MMU-352371 https://reactome.org/PathwayBrowser/#/R-MMU-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Mus musculus 29101 R-MMU-352379 https://reactome.org/PathwayBrowser/#/R-MMU-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Mus musculus 29101 R-MMU-352385 https://reactome.org/PathwayBrowser/#/R-MMU-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Mus musculus 29101 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-379393 https://reactome.org/PathwayBrowser/#/R-MMU-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-379415 https://reactome.org/PathwayBrowser/#/R-MMU-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Mus musculus 29101 R-MMU-379426 https://reactome.org/PathwayBrowser/#/R-MMU-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Mus musculus 29101 R-MMU-399711 https://reactome.org/PathwayBrowser/#/R-MMU-399711 Activation of Ca impermeable AMPA receptors IEA Mus musculus 29101 R-MMU-420980 https://reactome.org/PathwayBrowser/#/R-MMU-420980 Activation of Ca permeable AMPA receptors IEA Mus musculus 29101 R-MMU-425483 https://reactome.org/PathwayBrowser/#/R-MMU-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Mus musculus 29101 R-MMU-425577 https://reactome.org/PathwayBrowser/#/R-MMU-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Mus musculus 29101 R-MMU-425661 https://reactome.org/PathwayBrowser/#/R-MMU-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Mus musculus 29101 R-MMU-425678 https://reactome.org/PathwayBrowser/#/R-MMU-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Mus musculus 29101 R-MMU-425965 https://reactome.org/PathwayBrowser/#/R-MMU-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Mus musculus 29101 R-MMU-425983 https://reactome.org/PathwayBrowser/#/R-MMU-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Mus musculus 29101 R-MMU-425994 https://reactome.org/PathwayBrowser/#/R-MMU-425994 Na+/H+ exchanger transport (at cell membrane) IEA Mus musculus 29101 R-MMU-426015 https://reactome.org/PathwayBrowser/#/R-MMU-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Mus musculus 29101 R-MMU-426086 https://reactome.org/PathwayBrowser/#/R-MMU-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-426130 https://reactome.org/PathwayBrowser/#/R-MMU-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-426223 https://reactome.org/PathwayBrowser/#/R-MMU-426223 Cation influx mediated by TRPC3/6/7 IEA Mus musculus 29101 R-MMU-427605 https://reactome.org/PathwayBrowser/#/R-MMU-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-427645 https://reactome.org/PathwayBrowser/#/R-MMU-427645 SLC34A3 cotransports Pi, 2Na+ IEA Mus musculus 29101 R-MMU-427656 https://reactome.org/PathwayBrowser/#/R-MMU-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-428015 https://reactome.org/PathwayBrowser/#/R-MMU-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-428609 https://reactome.org/PathwayBrowser/#/R-MMU-428609 Type I Na+-coupled phosphate co-transport IEA Mus musculus 29101 R-MMU-429567 https://reactome.org/PathwayBrowser/#/R-MMU-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Mus musculus 29101 R-MMU-429571 https://reactome.org/PathwayBrowser/#/R-MMU-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Mus musculus 29101 R-MMU-429581 https://reactome.org/PathwayBrowser/#/R-MMU-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-429591 https://reactome.org/PathwayBrowser/#/R-MMU-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-429594 https://reactome.org/PathwayBrowser/#/R-MMU-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-429613 https://reactome.org/PathwayBrowser/#/R-MMU-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-429663 https://reactome.org/PathwayBrowser/#/R-MMU-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-433089 https://reactome.org/PathwayBrowser/#/R-MMU-433089 SOAT can transport taurolithocholate-3-sulphate IEA Mus musculus 29101 R-MMU-433099 https://reactome.org/PathwayBrowser/#/R-MMU-433099 NaS2 co-transports sulphate and two sodium ions IEA Mus musculus 29101 R-MMU-433101 https://reactome.org/PathwayBrowser/#/R-MMU-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Mus musculus 29101 R-MMU-433104 https://reactome.org/PathwayBrowser/#/R-MMU-433104 NACT co-transports trivalent citrate and a sodium ion IEA Mus musculus 29101 R-MMU-433114 https://reactome.org/PathwayBrowser/#/R-MMU-433114 NaS1 co-transports sulphate and a sodium ion IEA Mus musculus 29101 R-MMU-433131 https://reactome.org/PathwayBrowser/#/R-MMU-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Mus musculus 29101 R-MMU-438037 https://reactome.org/PathwayBrowser/#/R-MMU-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Mus musculus 29101 R-MMU-443997 https://reactome.org/PathwayBrowser/#/R-MMU-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-444007 https://reactome.org/PathwayBrowser/#/R-MMU-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Mus musculus 29101 R-MMU-444008 https://reactome.org/PathwayBrowser/#/R-MMU-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-444100 https://reactome.org/PathwayBrowser/#/R-MMU-444100 PROT mediates L-proline uptake IEA Mus musculus 29101 R-MMU-444120 https://reactome.org/PathwayBrowser/#/R-MMU-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-451310 https://reactome.org/PathwayBrowser/#/R-MMU-451310 Activation of Edited Kainate receptors IEA Mus musculus 29101 R-MMU-549241 https://reactome.org/PathwayBrowser/#/R-MMU-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-549297 https://reactome.org/PathwayBrowser/#/R-MMU-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-5626316 https://reactome.org/PathwayBrowser/#/R-MMU-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Mus musculus 29101 R-MMU-622325 https://reactome.org/PathwayBrowser/#/R-MMU-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 29101 R-MMU-6798528 https://reactome.org/PathwayBrowser/#/R-MMU-6798528 S100A8:S100A9 binds Mn2+ IEA Mus musculus 29101 R-MMU-8865637 https://reactome.org/PathwayBrowser/#/R-MMU-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Mus musculus 29101 R-MMU-8876283 https://reactome.org/PathwayBrowser/#/R-MMU-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-8876312 https://reactome.org/PathwayBrowser/#/R-MMU-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-8878664 https://reactome.org/PathwayBrowser/#/R-MMU-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Mus musculus 29101 R-MMU-8932955 https://reactome.org/PathwayBrowser/#/R-MMU-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-8949688 https://reactome.org/PathwayBrowser/#/R-MMU-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Mus musculus 29101 R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 29101 R-MMU-9648983 https://reactome.org/PathwayBrowser/#/R-MMU-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Mus musculus 29101 R-MMU-9713672 https://reactome.org/PathwayBrowser/#/R-MMU-9713672 cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol TAS Mus musculus 29101 R-MMU-9717432 https://reactome.org/PathwayBrowser/#/R-MMU-9717432 Trpm4 transports Na+ from the extracellular region to the cytosol TAS Mus musculus 29101 R-MMU-9717433 https://reactome.org/PathwayBrowser/#/R-MMU-9717433 Trpm5 transports Na+ from the extracellular region to the cytosol TAS Mus musculus 29101 R-MMU-9717440 https://reactome.org/PathwayBrowser/#/R-MMU-9717440 Scn9a:Scn1b,2b,4b transports Na+ from the extracellular region to the cytosol TAS Mus musculus 29101 R-MMU-9717444 https://reactome.org/PathwayBrowser/#/R-MMU-9717444 Scn3a:Scn2b,4b transports Na+ from the extracellular region to the cytosol TAS Mus musculus 29101 R-MMU-9717445 https://reactome.org/PathwayBrowser/#/R-MMU-9717445 Scn2a:Scn1b,2b,4b transports Na+ from the extracellular region to the cytosol TAS Mus musculus 29101 R-MMU-9751037 https://reactome.org/PathwayBrowser/#/R-MMU-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-MMU-975311 https://reactome.org/PathwayBrowser/#/R-MMU-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Mus musculus 29101 R-MMU-9754934 https://reactome.org/PathwayBrowser/#/R-MMU-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Mus musculus 29101 R-NUL-8951809 https://reactome.org/PathwayBrowser/#/R-NUL-8951809 Slc8a3 (NCX3) exchanges sodium (cytosol) for calcium (mitochondrial intermembrane space) TAS Mus musculus 29101 R-PFA-200396 https://reactome.org/PathwayBrowser/#/R-PFA-200396 Creatine transport across the plasma membrane IEA Plasmodium falciparum 29101 R-PFA-351987 https://reactome.org/PathwayBrowser/#/R-PFA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Plasmodium falciparum 29101 R-PFA-352029 https://reactome.org/PathwayBrowser/#/R-PFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Plasmodium falciparum 29101 R-PFA-352052 https://reactome.org/PathwayBrowser/#/R-PFA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Plasmodium falciparum 29101 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 29101 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 29101 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 29101 R-PFA-379393 https://reactome.org/PathwayBrowser/#/R-PFA-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 29101 R-PFA-427605 https://reactome.org/PathwayBrowser/#/R-PFA-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 29101 R-PFA-443997 https://reactome.org/PathwayBrowser/#/R-PFA-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 29101 R-PFA-444007 https://reactome.org/PathwayBrowser/#/R-PFA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Plasmodium falciparum 29101 R-PFA-444008 https://reactome.org/PathwayBrowser/#/R-PFA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 29101 R-PFA-444100 https://reactome.org/PathwayBrowser/#/R-PFA-444100 PROT mediates L-proline uptake IEA Plasmodium falciparum 29101 R-PFA-444120 https://reactome.org/PathwayBrowser/#/R-PFA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 29101 R-PFA-8865637 https://reactome.org/PathwayBrowser/#/R-PFA-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Plasmodium falciparum 29101 R-RNO-109530 https://reactome.org/PathwayBrowser/#/R-RNO-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Rattus norvegicus 29101 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 29101 R-RNO-109539 https://reactome.org/PathwayBrowser/#/R-RNO-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Rattus norvegicus 29101 R-RNO-165026 https://reactome.org/PathwayBrowser/#/R-RNO-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Rattus norvegicus 29101 R-RNO-189208 https://reactome.org/PathwayBrowser/#/R-RNO-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-194121 https://reactome.org/PathwayBrowser/#/R-RNO-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-194187 https://reactome.org/PathwayBrowser/#/R-RNO-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-198870 https://reactome.org/PathwayBrowser/#/R-RNO-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-199206 https://reactome.org/PathwayBrowser/#/R-RNO-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Rattus norvegicus 29101 R-RNO-199219 https://reactome.org/PathwayBrowser/#/R-RNO-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Rattus norvegicus 29101 R-RNO-200396 https://reactome.org/PathwayBrowser/#/R-RNO-200396 Creatine transport across the plasma membrane IEA Rattus norvegicus 29101 R-RNO-209910 https://reactome.org/PathwayBrowser/#/R-RNO-209910 Iodide is taken up by thyroid epithelial cells IEA Rattus norvegicus 29101 R-RNO-210404 https://reactome.org/PathwayBrowser/#/R-RNO-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Rattus norvegicus 29101 R-RNO-212642 https://reactome.org/PathwayBrowser/#/R-RNO-212642 L-Glutamine transport into neurons IEA Rattus norvegicus 29101 R-RNO-2514867 https://reactome.org/PathwayBrowser/#/R-RNO-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Rattus norvegicus 29101 R-RNO-2671885 https://reactome.org/PathwayBrowser/#/R-RNO-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Rattus norvegicus 29101 R-RNO-2672334 https://reactome.org/PathwayBrowser/#/R-RNO-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Rattus norvegicus 29101 R-RNO-2730664 https://reactome.org/PathwayBrowser/#/R-RNO-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-2872498 https://reactome.org/PathwayBrowser/#/R-RNO-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Rattus norvegicus 29101 R-RNO-3295580 https://reactome.org/PathwayBrowser/#/R-RNO-3295580 TRPM4,5 transport extracellular Na+ to cytosol IEA Rattus norvegicus 29101 R-RNO-351987 https://reactome.org/PathwayBrowser/#/R-RNO-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Rattus norvegicus 29101 R-RNO-352029 https://reactome.org/PathwayBrowser/#/R-RNO-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Rattus norvegicus 29101 R-RNO-352052 https://reactome.org/PathwayBrowser/#/R-RNO-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 29101 R-RNO-352108 https://reactome.org/PathwayBrowser/#/R-RNO-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Rattus norvegicus 29101 R-RNO-352119 https://reactome.org/PathwayBrowser/#/R-RNO-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Rattus norvegicus 29101 R-RNO-352174 https://reactome.org/PathwayBrowser/#/R-RNO-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Rattus norvegicus 29101 R-RNO-352182 https://reactome.org/PathwayBrowser/#/R-RNO-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Rattus norvegicus 29101 R-RNO-352347 https://reactome.org/PathwayBrowser/#/R-RNO-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Rattus norvegicus 29101 R-RNO-352354 https://reactome.org/PathwayBrowser/#/R-RNO-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Rattus norvegicus 29101 R-RNO-352364 https://reactome.org/PathwayBrowser/#/R-RNO-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Rattus norvegicus 29101 R-RNO-352371 https://reactome.org/PathwayBrowser/#/R-RNO-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Rattus norvegicus 29101 R-RNO-352379 https://reactome.org/PathwayBrowser/#/R-RNO-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Rattus norvegicus 29101 R-RNO-352385 https://reactome.org/PathwayBrowser/#/R-RNO-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Rattus norvegicus 29101 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-379393 https://reactome.org/PathwayBrowser/#/R-RNO-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-379415 https://reactome.org/PathwayBrowser/#/R-RNO-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Rattus norvegicus 29101 R-RNO-379426 https://reactome.org/PathwayBrowser/#/R-RNO-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Rattus norvegicus 29101 R-RNO-399711 https://reactome.org/PathwayBrowser/#/R-RNO-399711 Activation of Ca impermeable AMPA receptors IEA Rattus norvegicus 29101 R-RNO-420980 https://reactome.org/PathwayBrowser/#/R-RNO-420980 Activation of Ca permeable AMPA receptors IEA Rattus norvegicus 29101 R-RNO-425483 https://reactome.org/PathwayBrowser/#/R-RNO-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Rattus norvegicus 29101 R-RNO-425577 https://reactome.org/PathwayBrowser/#/R-RNO-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Rattus norvegicus 29101 R-RNO-425661 https://reactome.org/PathwayBrowser/#/R-RNO-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Rattus norvegicus 29101 R-RNO-425678 https://reactome.org/PathwayBrowser/#/R-RNO-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Rattus norvegicus 29101 R-RNO-425965 https://reactome.org/PathwayBrowser/#/R-RNO-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Rattus norvegicus 29101 R-RNO-425983 https://reactome.org/PathwayBrowser/#/R-RNO-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Rattus norvegicus 29101 R-RNO-425994 https://reactome.org/PathwayBrowser/#/R-RNO-425994 Na+/H+ exchanger transport (at cell membrane) IEA Rattus norvegicus 29101 R-RNO-426015 https://reactome.org/PathwayBrowser/#/R-RNO-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Rattus norvegicus 29101 R-RNO-426086 https://reactome.org/PathwayBrowser/#/R-RNO-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-426130 https://reactome.org/PathwayBrowser/#/R-RNO-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-426223 https://reactome.org/PathwayBrowser/#/R-RNO-426223 Cation influx mediated by TRPC3/6/7 IEA Rattus norvegicus 29101 R-RNO-427605 https://reactome.org/PathwayBrowser/#/R-RNO-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-427645 https://reactome.org/PathwayBrowser/#/R-RNO-427645 SLC34A3 cotransports Pi, 2Na+ IEA Rattus norvegicus 29101 R-RNO-427656 https://reactome.org/PathwayBrowser/#/R-RNO-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-428015 https://reactome.org/PathwayBrowser/#/R-RNO-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-428609 https://reactome.org/PathwayBrowser/#/R-RNO-428609 Type I Na+-coupled phosphate co-transport IEA Rattus norvegicus 29101 R-RNO-429567 https://reactome.org/PathwayBrowser/#/R-RNO-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Rattus norvegicus 29101 R-RNO-429571 https://reactome.org/PathwayBrowser/#/R-RNO-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Rattus norvegicus 29101 R-RNO-429581 https://reactome.org/PathwayBrowser/#/R-RNO-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-429591 https://reactome.org/PathwayBrowser/#/R-RNO-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-429594 https://reactome.org/PathwayBrowser/#/R-RNO-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-429613 https://reactome.org/PathwayBrowser/#/R-RNO-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-429663 https://reactome.org/PathwayBrowser/#/R-RNO-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-433089 https://reactome.org/PathwayBrowser/#/R-RNO-433089 SOAT can transport taurolithocholate-3-sulphate IEA Rattus norvegicus 29101 R-RNO-433099 https://reactome.org/PathwayBrowser/#/R-RNO-433099 NaS2 co-transports sulphate and two sodium ions IEA Rattus norvegicus 29101 R-RNO-433101 https://reactome.org/PathwayBrowser/#/R-RNO-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Rattus norvegicus 29101 R-RNO-433104 https://reactome.org/PathwayBrowser/#/R-RNO-433104 NACT co-transports trivalent citrate and a sodium ion IEA Rattus norvegicus 29101 R-RNO-433114 https://reactome.org/PathwayBrowser/#/R-RNO-433114 NaS1 co-transports sulphate and a sodium ion IEA Rattus norvegicus 29101 R-RNO-433131 https://reactome.org/PathwayBrowser/#/R-RNO-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Rattus norvegicus 29101 R-RNO-438037 https://reactome.org/PathwayBrowser/#/R-RNO-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Rattus norvegicus 29101 R-RNO-443997 https://reactome.org/PathwayBrowser/#/R-RNO-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-444007 https://reactome.org/PathwayBrowser/#/R-RNO-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Rattus norvegicus 29101 R-RNO-444008 https://reactome.org/PathwayBrowser/#/R-RNO-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-444100 https://reactome.org/PathwayBrowser/#/R-RNO-444100 PROT mediates L-proline uptake IEA Rattus norvegicus 29101 R-RNO-444120 https://reactome.org/PathwayBrowser/#/R-RNO-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-451310 https://reactome.org/PathwayBrowser/#/R-RNO-451310 Activation of Edited Kainate receptors IEA Rattus norvegicus 29101 R-RNO-549241 https://reactome.org/PathwayBrowser/#/R-RNO-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-549297 https://reactome.org/PathwayBrowser/#/R-RNO-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-5626316 https://reactome.org/PathwayBrowser/#/R-RNO-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Rattus norvegicus 29101 R-RNO-622325 https://reactome.org/PathwayBrowser/#/R-RNO-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 29101 R-RNO-6798528 https://reactome.org/PathwayBrowser/#/R-RNO-6798528 S100A8:S100A9 binds Mn2+ IEA Rattus norvegicus 29101 R-RNO-8865637 https://reactome.org/PathwayBrowser/#/R-RNO-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Rattus norvegicus 29101 R-RNO-8876283 https://reactome.org/PathwayBrowser/#/R-RNO-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-8876312 https://reactome.org/PathwayBrowser/#/R-RNO-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-8878664 https://reactome.org/PathwayBrowser/#/R-RNO-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Rattus norvegicus 29101 R-RNO-8932955 https://reactome.org/PathwayBrowser/#/R-RNO-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-8949688 https://reactome.org/PathwayBrowser/#/R-RNO-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Rattus norvegicus 29101 R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 29101 R-RNO-9614351 https://reactome.org/PathwayBrowser/#/R-RNO-9614351 Unblocking of Grin1:Grin2 NMDA receptors TAS Rattus norvegicus 29101 R-RNO-9648983 https://reactome.org/PathwayBrowser/#/R-RNO-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Rattus norvegicus 29101 R-RNO-9713740 https://reactome.org/PathwayBrowser/#/R-RNO-9713740 cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol TAS Rattus norvegicus 29101 R-RNO-9751037 https://reactome.org/PathwayBrowser/#/R-RNO-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-RNO-975311 https://reactome.org/PathwayBrowser/#/R-RNO-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Rattus norvegicus 29101 R-RNO-9754934 https://reactome.org/PathwayBrowser/#/R-RNO-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Rattus norvegicus 29101 R-SCE-212642 https://reactome.org/PathwayBrowser/#/R-SCE-212642 L-Glutamine transport into neurons IEA Saccharomyces cerevisiae 29101 R-SCE-352108 https://reactome.org/PathwayBrowser/#/R-SCE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 29101 R-SCE-352119 https://reactome.org/PathwayBrowser/#/R-SCE-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 29101 R-SCE-352174 https://reactome.org/PathwayBrowser/#/R-SCE-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Saccharomyces cerevisiae 29101 R-SCE-352182 https://reactome.org/PathwayBrowser/#/R-SCE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Saccharomyces cerevisiae 29101 R-SCE-425965 https://reactome.org/PathwayBrowser/#/R-SCE-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Saccharomyces cerevisiae 29101 R-SCE-425983 https://reactome.org/PathwayBrowser/#/R-SCE-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Saccharomyces cerevisiae 29101 R-SCE-425994 https://reactome.org/PathwayBrowser/#/R-SCE-425994 Na+/H+ exchanger transport (at cell membrane) IEA Saccharomyces cerevisiae 29101 R-SCE-426015 https://reactome.org/PathwayBrowser/#/R-SCE-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Saccharomyces cerevisiae 29101 R-SCE-427605 https://reactome.org/PathwayBrowser/#/R-SCE-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 29101 R-SCE-8949688 https://reactome.org/PathwayBrowser/#/R-SCE-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Saccharomyces cerevisiae 29101 R-SPO-425965 https://reactome.org/PathwayBrowser/#/R-SPO-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Schizosaccharomyces pombe 29101 R-SPO-425983 https://reactome.org/PathwayBrowser/#/R-SPO-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Schizosaccharomyces pombe 29101 R-SPO-425994 https://reactome.org/PathwayBrowser/#/R-SPO-425994 Na+/H+ exchanger transport (at cell membrane) IEA Schizosaccharomyces pombe 29101 R-SPO-426015 https://reactome.org/PathwayBrowser/#/R-SPO-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Schizosaccharomyces pombe 29101 R-SPO-8949688 https://reactome.org/PathwayBrowser/#/R-SPO-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Schizosaccharomyces pombe 29101 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa 29101 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 29101 R-SSC-109539 https://reactome.org/PathwayBrowser/#/R-SSC-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Sus scrofa 29101 R-SSC-165026 https://reactome.org/PathwayBrowser/#/R-SSC-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Sus scrofa 29101 R-SSC-189208 https://reactome.org/PathwayBrowser/#/R-SSC-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-194121 https://reactome.org/PathwayBrowser/#/R-SSC-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-198870 https://reactome.org/PathwayBrowser/#/R-SSC-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-199206 https://reactome.org/PathwayBrowser/#/R-SSC-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Sus scrofa 29101 R-SSC-199219 https://reactome.org/PathwayBrowser/#/R-SSC-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Sus scrofa 29101 R-SSC-200396 https://reactome.org/PathwayBrowser/#/R-SSC-200396 Creatine transport across the plasma membrane IEA Sus scrofa 29101 R-SSC-209910 https://reactome.org/PathwayBrowser/#/R-SSC-209910 Iodide is taken up by thyroid epithelial cells IEA Sus scrofa 29101 R-SSC-210404 https://reactome.org/PathwayBrowser/#/R-SSC-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Sus scrofa 29101 R-SSC-212642 https://reactome.org/PathwayBrowser/#/R-SSC-212642 L-Glutamine transport into neurons IEA Sus scrofa 29101 R-SSC-2514867 https://reactome.org/PathwayBrowser/#/R-SSC-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Sus scrofa 29101 R-SSC-2671885 https://reactome.org/PathwayBrowser/#/R-SSC-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Sus scrofa 29101 R-SSC-2672334 https://reactome.org/PathwayBrowser/#/R-SSC-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Sus scrofa 29101 R-SSC-2730664 https://reactome.org/PathwayBrowser/#/R-SSC-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-2872444 https://reactome.org/PathwayBrowser/#/R-SSC-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Sus scrofa 29101 R-SSC-2872498 https://reactome.org/PathwayBrowser/#/R-SSC-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Sus scrofa 29101 R-SSC-2889070 https://reactome.org/PathwayBrowser/#/R-SSC-2889070 SLC9B2 exchanges Na+ for H+ IEA Sus scrofa 29101 R-SSC-3295580 https://reactome.org/PathwayBrowser/#/R-SSC-3295580 TRPM4,5 transport extracellular Na+ to cytosol IEA Sus scrofa 29101 R-SSC-351987 https://reactome.org/PathwayBrowser/#/R-SSC-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Sus scrofa 29101 R-SSC-352029 https://reactome.org/PathwayBrowser/#/R-SSC-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Sus scrofa 29101 R-SSC-352052 https://reactome.org/PathwayBrowser/#/R-SSC-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 29101 R-SSC-352108 https://reactome.org/PathwayBrowser/#/R-SSC-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Sus scrofa 29101 R-SSC-352119 https://reactome.org/PathwayBrowser/#/R-SSC-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Sus scrofa 29101 R-SSC-352174 https://reactome.org/PathwayBrowser/#/R-SSC-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Sus scrofa 29101 R-SSC-352182 https://reactome.org/PathwayBrowser/#/R-SSC-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Sus scrofa 29101 R-SSC-352347 https://reactome.org/PathwayBrowser/#/R-SSC-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Sus scrofa 29101 R-SSC-352354 https://reactome.org/PathwayBrowser/#/R-SSC-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Sus scrofa 29101 R-SSC-352364 https://reactome.org/PathwayBrowser/#/R-SSC-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Sus scrofa 29101 R-SSC-352371 https://reactome.org/PathwayBrowser/#/R-SSC-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Sus scrofa 29101 R-SSC-352379 https://reactome.org/PathwayBrowser/#/R-SSC-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Sus scrofa 29101 R-SSC-352385 https://reactome.org/PathwayBrowser/#/R-SSC-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Sus scrofa 29101 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-379393 https://reactome.org/PathwayBrowser/#/R-SSC-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-379415 https://reactome.org/PathwayBrowser/#/R-SSC-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Sus scrofa 29101 R-SSC-399711 https://reactome.org/PathwayBrowser/#/R-SSC-399711 Activation of Ca impermeable AMPA receptors IEA Sus scrofa 29101 R-SSC-420980 https://reactome.org/PathwayBrowser/#/R-SSC-420980 Activation of Ca permeable AMPA receptors IEA Sus scrofa 29101 R-SSC-425483 https://reactome.org/PathwayBrowser/#/R-SSC-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Sus scrofa 29101 R-SSC-425577 https://reactome.org/PathwayBrowser/#/R-SSC-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Sus scrofa 29101 R-SSC-425661 https://reactome.org/PathwayBrowser/#/R-SSC-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Sus scrofa 29101 R-SSC-425678 https://reactome.org/PathwayBrowser/#/R-SSC-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Sus scrofa 29101 R-SSC-425965 https://reactome.org/PathwayBrowser/#/R-SSC-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Sus scrofa 29101 R-SSC-425983 https://reactome.org/PathwayBrowser/#/R-SSC-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Sus scrofa 29101 R-SSC-425994 https://reactome.org/PathwayBrowser/#/R-SSC-425994 Na+/H+ exchanger transport (at cell membrane) IEA Sus scrofa 29101 R-SSC-426015 https://reactome.org/PathwayBrowser/#/R-SSC-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Sus scrofa 29101 R-SSC-426086 https://reactome.org/PathwayBrowser/#/R-SSC-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-426130 https://reactome.org/PathwayBrowser/#/R-SSC-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-426223 https://reactome.org/PathwayBrowser/#/R-SSC-426223 Cation influx mediated by TRPC3/6/7 IEA Sus scrofa 29101 R-SSC-427605 https://reactome.org/PathwayBrowser/#/R-SSC-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-427645 https://reactome.org/PathwayBrowser/#/R-SSC-427645 SLC34A3 cotransports Pi, 2Na+ IEA Sus scrofa 29101 R-SSC-427656 https://reactome.org/PathwayBrowser/#/R-SSC-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-428015 https://reactome.org/PathwayBrowser/#/R-SSC-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-428609 https://reactome.org/PathwayBrowser/#/R-SSC-428609 Type I Na+-coupled phosphate co-transport IEA Sus scrofa 29101 R-SSC-429567 https://reactome.org/PathwayBrowser/#/R-SSC-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Sus scrofa 29101 R-SSC-429571 https://reactome.org/PathwayBrowser/#/R-SSC-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Sus scrofa 29101 R-SSC-429581 https://reactome.org/PathwayBrowser/#/R-SSC-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-429591 https://reactome.org/PathwayBrowser/#/R-SSC-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-429594 https://reactome.org/PathwayBrowser/#/R-SSC-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-429613 https://reactome.org/PathwayBrowser/#/R-SSC-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-429663 https://reactome.org/PathwayBrowser/#/R-SSC-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-433089 https://reactome.org/PathwayBrowser/#/R-SSC-433089 SOAT can transport taurolithocholate-3-sulphate IEA Sus scrofa 29101 R-SSC-433099 https://reactome.org/PathwayBrowser/#/R-SSC-433099 NaS2 co-transports sulphate and two sodium ions IEA Sus scrofa 29101 R-SSC-433101 https://reactome.org/PathwayBrowser/#/R-SSC-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Sus scrofa 29101 R-SSC-433104 https://reactome.org/PathwayBrowser/#/R-SSC-433104 NACT co-transports trivalent citrate and a sodium ion IEA Sus scrofa 29101 R-SSC-433114 https://reactome.org/PathwayBrowser/#/R-SSC-433114 NaS1 co-transports sulphate and a sodium ion IEA Sus scrofa 29101 R-SSC-433131 https://reactome.org/PathwayBrowser/#/R-SSC-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Sus scrofa 29101 R-SSC-438037 https://reactome.org/PathwayBrowser/#/R-SSC-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Sus scrofa 29101 R-SSC-443997 https://reactome.org/PathwayBrowser/#/R-SSC-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-444007 https://reactome.org/PathwayBrowser/#/R-SSC-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Sus scrofa 29101 R-SSC-444008 https://reactome.org/PathwayBrowser/#/R-SSC-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-444100 https://reactome.org/PathwayBrowser/#/R-SSC-444100 PROT mediates L-proline uptake IEA Sus scrofa 29101 R-SSC-444120 https://reactome.org/PathwayBrowser/#/R-SSC-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-451310 https://reactome.org/PathwayBrowser/#/R-SSC-451310 Activation of Edited Kainate receptors IEA Sus scrofa 29101 R-SSC-549241 https://reactome.org/PathwayBrowser/#/R-SSC-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-549297 https://reactome.org/PathwayBrowser/#/R-SSC-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-5626316 https://reactome.org/PathwayBrowser/#/R-SSC-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Sus scrofa 29101 R-SSC-6798528 https://reactome.org/PathwayBrowser/#/R-SSC-6798528 S100A8:S100A9 binds Mn2+ IEA Sus scrofa 29101 R-SSC-8865637 https://reactome.org/PathwayBrowser/#/R-SSC-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Sus scrofa 29101 R-SSC-8876283 https://reactome.org/PathwayBrowser/#/R-SSC-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-8876312 https://reactome.org/PathwayBrowser/#/R-SSC-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-8878664 https://reactome.org/PathwayBrowser/#/R-SSC-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Sus scrofa 29101 R-SSC-8932955 https://reactome.org/PathwayBrowser/#/R-SSC-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-8949688 https://reactome.org/PathwayBrowser/#/R-SSC-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Sus scrofa 29101 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 29101 R-SSC-9648983 https://reactome.org/PathwayBrowser/#/R-SSC-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Sus scrofa 29101 R-SSC-9751037 https://reactome.org/PathwayBrowser/#/R-SSC-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-SSC-975311 https://reactome.org/PathwayBrowser/#/R-SSC-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Sus scrofa 29101 R-SSC-9754934 https://reactome.org/PathwayBrowser/#/R-SSC-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Sus scrofa 29101 R-XTR-109530 https://reactome.org/PathwayBrowser/#/R-XTR-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Xenopus tropicalis 29101 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 29101 R-XTR-109539 https://reactome.org/PathwayBrowser/#/R-XTR-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Xenopus tropicalis 29101 R-XTR-165026 https://reactome.org/PathwayBrowser/#/R-XTR-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Xenopus tropicalis 29101 R-XTR-189208 https://reactome.org/PathwayBrowser/#/R-XTR-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-194121 https://reactome.org/PathwayBrowser/#/R-XTR-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-194187 https://reactome.org/PathwayBrowser/#/R-XTR-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-198870 https://reactome.org/PathwayBrowser/#/R-XTR-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-199206 https://reactome.org/PathwayBrowser/#/R-XTR-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Xenopus tropicalis 29101 R-XTR-199219 https://reactome.org/PathwayBrowser/#/R-XTR-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Xenopus tropicalis 29101 R-XTR-200396 https://reactome.org/PathwayBrowser/#/R-XTR-200396 Creatine transport across the plasma membrane IEA Xenopus tropicalis 29101 R-XTR-209910 https://reactome.org/PathwayBrowser/#/R-XTR-209910 Iodide is taken up by thyroid epithelial cells IEA Xenopus tropicalis 29101 R-XTR-210404 https://reactome.org/PathwayBrowser/#/R-XTR-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Xenopus tropicalis 29101 R-XTR-212642 https://reactome.org/PathwayBrowser/#/R-XTR-212642 L-Glutamine transport into neurons IEA Xenopus tropicalis 29101 R-XTR-2671885 https://reactome.org/PathwayBrowser/#/R-XTR-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Xenopus tropicalis 29101 R-XTR-2672334 https://reactome.org/PathwayBrowser/#/R-XTR-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Xenopus tropicalis 29101 R-XTR-2872444 https://reactome.org/PathwayBrowser/#/R-XTR-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Xenopus tropicalis 29101 R-XTR-2889070 https://reactome.org/PathwayBrowser/#/R-XTR-2889070 SLC9B2 exchanges Na+ for H+ IEA Xenopus tropicalis 29101 R-XTR-351987 https://reactome.org/PathwayBrowser/#/R-XTR-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Xenopus tropicalis 29101 R-XTR-352029 https://reactome.org/PathwayBrowser/#/R-XTR-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Xenopus tropicalis 29101 R-XTR-352052 https://reactome.org/PathwayBrowser/#/R-XTR-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 29101 R-XTR-352108 https://reactome.org/PathwayBrowser/#/R-XTR-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 29101 R-XTR-352119 https://reactome.org/PathwayBrowser/#/R-XTR-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 29101 R-XTR-352174 https://reactome.org/PathwayBrowser/#/R-XTR-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Xenopus tropicalis 29101 R-XTR-352182 https://reactome.org/PathwayBrowser/#/R-XTR-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Xenopus tropicalis 29101 R-XTR-352347 https://reactome.org/PathwayBrowser/#/R-XTR-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Xenopus tropicalis 29101 R-XTR-352354 https://reactome.org/PathwayBrowser/#/R-XTR-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Xenopus tropicalis 29101 R-XTR-352364 https://reactome.org/PathwayBrowser/#/R-XTR-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Xenopus tropicalis 29101 R-XTR-352371 https://reactome.org/PathwayBrowser/#/R-XTR-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Xenopus tropicalis 29101 R-XTR-352379 https://reactome.org/PathwayBrowser/#/R-XTR-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Xenopus tropicalis 29101 R-XTR-352385 https://reactome.org/PathwayBrowser/#/R-XTR-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Xenopus tropicalis 29101 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-379393 https://reactome.org/PathwayBrowser/#/R-XTR-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-379415 https://reactome.org/PathwayBrowser/#/R-XTR-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Xenopus tropicalis 29101 R-XTR-379426 https://reactome.org/PathwayBrowser/#/R-XTR-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Xenopus tropicalis 29101 R-XTR-425483 https://reactome.org/PathwayBrowser/#/R-XTR-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Xenopus tropicalis 29101 R-XTR-425577 https://reactome.org/PathwayBrowser/#/R-XTR-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Xenopus tropicalis 29101 R-XTR-425661 https://reactome.org/PathwayBrowser/#/R-XTR-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Xenopus tropicalis 29101 R-XTR-425678 https://reactome.org/PathwayBrowser/#/R-XTR-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Xenopus tropicalis 29101 R-XTR-425965 https://reactome.org/PathwayBrowser/#/R-XTR-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Xenopus tropicalis 29101 R-XTR-425983 https://reactome.org/PathwayBrowser/#/R-XTR-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Xenopus tropicalis 29101 R-XTR-425994 https://reactome.org/PathwayBrowser/#/R-XTR-425994 Na+/H+ exchanger transport (at cell membrane) IEA Xenopus tropicalis 29101 R-XTR-426015 https://reactome.org/PathwayBrowser/#/R-XTR-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Xenopus tropicalis 29101 R-XTR-426086 https://reactome.org/PathwayBrowser/#/R-XTR-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-426130 https://reactome.org/PathwayBrowser/#/R-XTR-426130 SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-426223 https://reactome.org/PathwayBrowser/#/R-XTR-426223 Cation influx mediated by TRPC3/6/7 IEA Xenopus tropicalis 29101 R-XTR-427605 https://reactome.org/PathwayBrowser/#/R-XTR-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-427645 https://reactome.org/PathwayBrowser/#/R-XTR-427645 SLC34A3 cotransports Pi, 2Na+ IEA Xenopus tropicalis 29101 R-XTR-428015 https://reactome.org/PathwayBrowser/#/R-XTR-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-429571 https://reactome.org/PathwayBrowser/#/R-XTR-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Xenopus tropicalis 29101 R-XTR-429581 https://reactome.org/PathwayBrowser/#/R-XTR-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-429591 https://reactome.org/PathwayBrowser/#/R-XTR-429591 SLC5A5 cotransports Na+ with I- from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-429594 https://reactome.org/PathwayBrowser/#/R-XTR-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-429613 https://reactome.org/PathwayBrowser/#/R-XTR-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-433089 https://reactome.org/PathwayBrowser/#/R-XTR-433089 SOAT can transport taurolithocholate-3-sulphate IEA Xenopus tropicalis 29101 R-XTR-433101 https://reactome.org/PathwayBrowser/#/R-XTR-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Xenopus tropicalis 29101 R-XTR-433104 https://reactome.org/PathwayBrowser/#/R-XTR-433104 NACT co-transports trivalent citrate and a sodium ion IEA Xenopus tropicalis 29101 R-XTR-433114 https://reactome.org/PathwayBrowser/#/R-XTR-433114 NaS1 co-transports sulphate and a sodium ion IEA Xenopus tropicalis 29101 R-XTR-433131 https://reactome.org/PathwayBrowser/#/R-XTR-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Xenopus tropicalis 29101 R-XTR-443997 https://reactome.org/PathwayBrowser/#/R-XTR-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-444007 https://reactome.org/PathwayBrowser/#/R-XTR-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Xenopus tropicalis 29101 R-XTR-444008 https://reactome.org/PathwayBrowser/#/R-XTR-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-444100 https://reactome.org/PathwayBrowser/#/R-XTR-444100 PROT mediates L-proline uptake IEA Xenopus tropicalis 29101 R-XTR-444120 https://reactome.org/PathwayBrowser/#/R-XTR-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-549241 https://reactome.org/PathwayBrowser/#/R-XTR-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-549297 https://reactome.org/PathwayBrowser/#/R-XTR-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-5626316 https://reactome.org/PathwayBrowser/#/R-XTR-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Xenopus tropicalis 29101 R-XTR-622325 https://reactome.org/PathwayBrowser/#/R-XTR-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 29101 R-XTR-6798528 https://reactome.org/PathwayBrowser/#/R-XTR-6798528 S100A8:S100A9 binds Mn2+ IEA Xenopus tropicalis 29101 R-XTR-8865637 https://reactome.org/PathwayBrowser/#/R-XTR-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Xenopus tropicalis 29101 R-XTR-8876283 https://reactome.org/PathwayBrowser/#/R-XTR-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-8876312 https://reactome.org/PathwayBrowser/#/R-XTR-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-8878664 https://reactome.org/PathwayBrowser/#/R-XTR-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Xenopus tropicalis 29101 R-XTR-8932955 https://reactome.org/PathwayBrowser/#/R-XTR-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 29101 R-XTR-9751037 https://reactome.org/PathwayBrowser/#/R-XTR-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29101 R-XTR-9754934 https://reactome.org/PathwayBrowser/#/R-XTR-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29103 R-BTA-1013020 https://reactome.org/PathwayBrowser/#/R-BTA-1013020 Activation of GIRK/Kir3 Channels IEA Bos taurus 29103 R-BTA-1296024 https://reactome.org/PathwayBrowser/#/R-BTA-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Bos taurus 29103 R-BTA-1296037 https://reactome.org/PathwayBrowser/#/R-BTA-1296037 Activation of Ca2+ activated Potassium channels with large conductance IEA Bos taurus 29103 R-BTA-1296039 https://reactome.org/PathwayBrowser/#/R-BTA-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Bos taurus 29103 R-BTA-1296043 https://reactome.org/PathwayBrowser/#/R-BTA-1296043 Activation of HCN channels IEA Bos taurus 29103 R-BTA-1296045 https://reactome.org/PathwayBrowser/#/R-BTA-1296045 Activation of Potassium transport channels IEA Bos taurus 29103 R-BTA-1296046 https://reactome.org/PathwayBrowser/#/R-BTA-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Bos taurus 29103 R-BTA-1296127 https://reactome.org/PathwayBrowser/#/R-BTA-1296127 Activation of voltage gated Potassium channels IEA Bos taurus 29103 R-BTA-1296348 https://reactome.org/PathwayBrowser/#/R-BTA-1296348 Activation of TWIK-related K+ channel (TREK) IEA Bos taurus 29103 R-BTA-1299297 https://reactome.org/PathwayBrowser/#/R-BTA-1299297 Activation of THIK IEA Bos taurus 29103 R-BTA-1299304 https://reactome.org/PathwayBrowser/#/R-BTA-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels IEA Bos taurus 29103 R-BTA-1299318 https://reactome.org/PathwayBrowser/#/R-BTA-1299318 Activation of TASK IEA Bos taurus 29103 R-BTA-1299338 https://reactome.org/PathwayBrowser/#/R-BTA-1299338 Activation of TRESK IEA Bos taurus 29103 R-BTA-1299359 https://reactome.org/PathwayBrowser/#/R-BTA-1299359 Activation of TALK IEA Bos taurus 29103 R-BTA-1369017 https://reactome.org/PathwayBrowser/#/R-BTA-1369017 Activation of ATP sensitive Potassium channels in muscle cells IEA Bos taurus 29103 R-BTA-174391 https://reactome.org/PathwayBrowser/#/R-BTA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Bos taurus 29103 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 29103 R-BTA-204169 https://reactome.org/PathwayBrowser/#/R-BTA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Bos taurus 29103 R-BTA-210404 https://reactome.org/PathwayBrowser/#/R-BTA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Bos taurus 29103 R-BTA-210420 https://reactome.org/PathwayBrowser/#/R-BTA-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Bos taurus 29103 R-BTA-2408551 https://reactome.org/PathwayBrowser/#/R-BTA-2408551 SeMet is converted to AdoSeMet by MAT IEA Bos taurus 29103 R-BTA-2534148 https://reactome.org/PathwayBrowser/#/R-BTA-2534148 Nckx1 exchanges Na+ for Ca2+/K+ TAS Bos taurus 29103 R-BTA-2534365 https://reactome.org/PathwayBrowser/#/R-BTA-2534365 Slo3 Potassium Transport IEA Bos taurus 29103 R-BTA-375330 https://reactome.org/PathwayBrowser/#/R-BTA-375330 Connexin 45/Connexin 36 mediated neuronal gap junction communication IEA Bos taurus 29103 R-BTA-375339 https://reactome.org/PathwayBrowser/#/R-BTA-375339 Pannexin 1/Pannexin2 mediated neuronal gap junction communication IEA Bos taurus 29103 R-BTA-375340 https://reactome.org/PathwayBrowser/#/R-BTA-375340 Connexin 62 mediated neuronal gap junction communication IEA Bos taurus 29103 R-BTA-375342 https://reactome.org/PathwayBrowser/#/R-BTA-375342 Connexin 36 mediated neuronal gap junction communication IEA Bos taurus 29103 R-BTA-425678 https://reactome.org/PathwayBrowser/#/R-BTA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Bos taurus 29103 R-BTA-426086 https://reactome.org/PathwayBrowser/#/R-BTA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Bos taurus 29103 R-BTA-426155 https://reactome.org/PathwayBrowser/#/R-BTA-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Bos taurus 29103 R-BTA-428015 https://reactome.org/PathwayBrowser/#/R-BTA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Bos taurus 29103 R-BTA-5577050 https://reactome.org/PathwayBrowser/#/R-BTA-5577050 AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region IEA Bos taurus 29103 R-BTA-5577234 https://reactome.org/PathwayBrowser/#/R-BTA-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Bos taurus 29103 R-BTA-5577237 https://reactome.org/PathwayBrowser/#/R-BTA-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region IEA Bos taurus 29103 R-BTA-5578910 https://reactome.org/PathwayBrowser/#/R-BTA-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Bos taurus 29103 R-BTA-5603114 https://reactome.org/PathwayBrowser/#/R-BTA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Bos taurus 29103 R-BTA-5626316 https://reactome.org/PathwayBrowser/#/R-BTA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Bos taurus 29103 R-BTA-5678261 https://reactome.org/PathwayBrowser/#/R-BTA-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol IEA Bos taurus 29103 R-BTA-5693148 https://reactome.org/PathwayBrowser/#/R-BTA-5693148 BCKDK phosphorylates BCKDH IEA Bos taurus 29103 R-BTA-5693153 https://reactome.org/PathwayBrowser/#/R-BTA-5693153 PPM1K dephosphorylates p-BCKDH IEA Bos taurus 29103 R-BTA-70333 https://reactome.org/PathwayBrowser/#/R-BTA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Bos taurus 29103 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 29103 R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 29103 R-BTA-877187 https://reactome.org/PathwayBrowser/#/R-BTA-877187 P2X7 mediates loss of intracellular K+ IEA Bos taurus 29103 R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 29103 R-BTA-937311 https://reactome.org/PathwayBrowser/#/R-BTA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Bos taurus 29103 R-BTA-9648983 https://reactome.org/PathwayBrowser/#/R-BTA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Bos taurus 29103 R-BTA-9727198 https://reactome.org/PathwayBrowser/#/R-BTA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Bos taurus 29103 R-BTA-975311 https://reactome.org/PathwayBrowser/#/R-BTA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Bos taurus 29103 R-BTA-9861616 https://reactome.org/PathwayBrowser/#/R-BTA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 29103 R-BTA-9861667 https://reactome.org/PathwayBrowser/#/R-BTA-9861667 DLAT trimer transfers acetyl to CoA IEA Bos taurus 29103 R-BTA-9861734 https://reactome.org/PathwayBrowser/#/R-BTA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Bos taurus 29103 R-CEL-1013020 https://reactome.org/PathwayBrowser/#/R-CEL-1013020 Activation of GIRK/Kir3 Channels IEA Caenorhabditis elegans 29103 R-CEL-1296035 https://reactome.org/PathwayBrowser/#/R-CEL-1296035 Activation of Ca2+ activated Potassium channels with Intermediate conductance IEA Caenorhabditis elegans 29103 R-CEL-1296039 https://reactome.org/PathwayBrowser/#/R-CEL-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Caenorhabditis elegans 29103 R-CEL-1296045 https://reactome.org/PathwayBrowser/#/R-CEL-1296045 Activation of Potassium transport channels IEA Caenorhabditis elegans 29103 R-CEL-1296046 https://reactome.org/PathwayBrowser/#/R-CEL-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Caenorhabditis elegans 29103 R-CEL-1296348 https://reactome.org/PathwayBrowser/#/R-CEL-1296348 Activation of TWIK-related K+ channel (TREK) IEA Caenorhabditis elegans 29103 R-CEL-1299297 https://reactome.org/PathwayBrowser/#/R-CEL-1299297 Activation of THIK IEA Caenorhabditis elegans 29103 R-CEL-1299304 https://reactome.org/PathwayBrowser/#/R-CEL-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels IEA Caenorhabditis elegans 29103 R-CEL-1299318 https://reactome.org/PathwayBrowser/#/R-CEL-1299318 Activation of TASK IEA Caenorhabditis elegans 29103 R-CEL-1299338 https://reactome.org/PathwayBrowser/#/R-CEL-1299338 Activation of TRESK IEA Caenorhabditis elegans 29103 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 29103 R-CEL-204169 https://reactome.org/PathwayBrowser/#/R-CEL-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Caenorhabditis elegans 29103 R-CEL-210404 https://reactome.org/PathwayBrowser/#/R-CEL-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Caenorhabditis elegans 29103 R-CEL-210420 https://reactome.org/PathwayBrowser/#/R-CEL-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Caenorhabditis elegans 29103 R-CEL-2534365 https://reactome.org/PathwayBrowser/#/R-CEL-2534365 Slo3 Potassium Transport IEA Caenorhabditis elegans 29103 R-CEL-425678 https://reactome.org/PathwayBrowser/#/R-CEL-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Caenorhabditis elegans 29103 R-CEL-426086 https://reactome.org/PathwayBrowser/#/R-CEL-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Caenorhabditis elegans 29103 R-CEL-426155 https://reactome.org/PathwayBrowser/#/R-CEL-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Caenorhabditis elegans 29103 R-CEL-428015 https://reactome.org/PathwayBrowser/#/R-CEL-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29103 R-CEL-5577234 https://reactome.org/PathwayBrowser/#/R-CEL-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Caenorhabditis elegans 29103 R-CEL-5578910 https://reactome.org/PathwayBrowser/#/R-CEL-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Caenorhabditis elegans 29103 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 29103 R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 29103 R-CEL-9648983 https://reactome.org/PathwayBrowser/#/R-CEL-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Caenorhabditis elegans 29103 R-CEL-975311 https://reactome.org/PathwayBrowser/#/R-CEL-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Caenorhabditis elegans 29103 R-CEL-9861616 https://reactome.org/PathwayBrowser/#/R-CEL-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 29103 R-CEL-9861667 https://reactome.org/PathwayBrowser/#/R-CEL-9861667 DLAT trimer transfers acetyl to CoA IEA Caenorhabditis elegans 29103 R-CEL-9861734 https://reactome.org/PathwayBrowser/#/R-CEL-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Caenorhabditis elegans 29103 R-CFA-1013020 https://reactome.org/PathwayBrowser/#/R-CFA-1013020 Activation of GIRK/Kir3 Channels IEA Canis familiaris 29103 R-CFA-1296024 https://reactome.org/PathwayBrowser/#/R-CFA-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Canis familiaris 29103 R-CFA-1296035 https://reactome.org/PathwayBrowser/#/R-CFA-1296035 Activation of Ca2+ activated Potassium channels with Intermediate conductance IEA Canis familiaris 29103 R-CFA-1296037 https://reactome.org/PathwayBrowser/#/R-CFA-1296037 Activation of Ca2+ activated Potassium channels with large conductance IEA Canis familiaris 29103 R-CFA-1296039 https://reactome.org/PathwayBrowser/#/R-CFA-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Canis familiaris 29103 R-CFA-1296043 https://reactome.org/PathwayBrowser/#/R-CFA-1296043 Activation of HCN channels IEA Canis familiaris 29103 R-CFA-1296045 https://reactome.org/PathwayBrowser/#/R-CFA-1296045 Activation of Potassium transport channels IEA Canis familiaris 29103 R-CFA-1296046 https://reactome.org/PathwayBrowser/#/R-CFA-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Canis familiaris 29103 R-CFA-1296127 https://reactome.org/PathwayBrowser/#/R-CFA-1296127 Activation of voltage gated Potassium channels IEA Canis familiaris 29103 R-CFA-1296348 https://reactome.org/PathwayBrowser/#/R-CFA-1296348 Activation of TWIK-related K+ channel (TREK) IEA Canis familiaris 29103 R-CFA-1299297 https://reactome.org/PathwayBrowser/#/R-CFA-1299297 Activation of THIK IEA Canis familiaris 29103 R-CFA-1299304 https://reactome.org/PathwayBrowser/#/R-CFA-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels IEA Canis familiaris 29103 R-CFA-1299318 https://reactome.org/PathwayBrowser/#/R-CFA-1299318 Activation of TASK IEA Canis familiaris 29103 R-CFA-1299338 https://reactome.org/PathwayBrowser/#/R-CFA-1299338 Activation of TRESK IEA Canis familiaris 29103 R-CFA-1299359 https://reactome.org/PathwayBrowser/#/R-CFA-1299359 Activation of TALK IEA Canis familiaris 29103 R-CFA-1369017 https://reactome.org/PathwayBrowser/#/R-CFA-1369017 Activation of ATP sensitive Potassium channels in muscle cells IEA Canis familiaris 29103 R-CFA-174391 https://reactome.org/PathwayBrowser/#/R-CFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Canis familiaris 29103 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 29103 R-CFA-204169 https://reactome.org/PathwayBrowser/#/R-CFA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Canis familiaris 29103 R-CFA-210404 https://reactome.org/PathwayBrowser/#/R-CFA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Canis familiaris 29103 R-CFA-210420 https://reactome.org/PathwayBrowser/#/R-CFA-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Canis familiaris 29103 R-CFA-2408551 https://reactome.org/PathwayBrowser/#/R-CFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Canis familiaris 29103 R-CFA-2534365 https://reactome.org/PathwayBrowser/#/R-CFA-2534365 Slo3 Potassium Transport IEA Canis familiaris 29103 R-CFA-375330 https://reactome.org/PathwayBrowser/#/R-CFA-375330 Connexin 45/Connexin 36 mediated neuronal gap junction communication IEA Canis familiaris 29103 R-CFA-375339 https://reactome.org/PathwayBrowser/#/R-CFA-375339 Pannexin 1/Pannexin2 mediated neuronal gap junction communication IEA Canis familiaris 29103 R-CFA-375340 https://reactome.org/PathwayBrowser/#/R-CFA-375340 Connexin 62 mediated neuronal gap junction communication IEA Canis familiaris 29103 R-CFA-375342 https://reactome.org/PathwayBrowser/#/R-CFA-375342 Connexin 36 mediated neuronal gap junction communication IEA Canis familiaris 29103 R-CFA-425678 https://reactome.org/PathwayBrowser/#/R-CFA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Canis familiaris 29103 R-CFA-426086 https://reactome.org/PathwayBrowser/#/R-CFA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Canis familiaris 29103 R-CFA-426155 https://reactome.org/PathwayBrowser/#/R-CFA-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Canis familiaris 29103 R-CFA-428015 https://reactome.org/PathwayBrowser/#/R-CFA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Canis familiaris 29103 R-CFA-5577234 https://reactome.org/PathwayBrowser/#/R-CFA-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Canis familiaris 29103 R-CFA-5577237 https://reactome.org/PathwayBrowser/#/R-CFA-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region IEA Canis familiaris 29103 R-CFA-5578910 https://reactome.org/PathwayBrowser/#/R-CFA-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Canis familiaris 29103 R-CFA-5603114 https://reactome.org/PathwayBrowser/#/R-CFA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Canis familiaris 29103 R-CFA-5626316 https://reactome.org/PathwayBrowser/#/R-CFA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Canis familiaris 29103 R-CFA-5678261 https://reactome.org/PathwayBrowser/#/R-CFA-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol IEA Canis familiaris 29103 R-CFA-5693148 https://reactome.org/PathwayBrowser/#/R-CFA-5693148 BCKDK phosphorylates BCKDH IEA Canis familiaris 29103 R-CFA-5693153 https://reactome.org/PathwayBrowser/#/R-CFA-5693153 PPM1K dephosphorylates p-BCKDH IEA Canis familiaris 29103 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 29103 R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 29103 R-CFA-877187 https://reactome.org/PathwayBrowser/#/R-CFA-877187 P2X7 mediates loss of intracellular K+ IEA Canis familiaris 29103 R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 29103 R-CFA-937311 https://reactome.org/PathwayBrowser/#/R-CFA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Canis familiaris 29103 R-CFA-9648983 https://reactome.org/PathwayBrowser/#/R-CFA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Canis familiaris 29103 R-CFA-9727198 https://reactome.org/PathwayBrowser/#/R-CFA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Canis familiaris 29103 R-CFA-975311 https://reactome.org/PathwayBrowser/#/R-CFA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Canis familiaris 29103 R-CFA-9861616 https://reactome.org/PathwayBrowser/#/R-CFA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 29103 R-CFA-9861667 https://reactome.org/PathwayBrowser/#/R-CFA-9861667 DLAT trimer transfers acetyl to CoA IEA Canis familiaris 29103 R-CFA-9861734 https://reactome.org/PathwayBrowser/#/R-CFA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Canis familiaris 29103 R-DDI-1296035 https://reactome.org/PathwayBrowser/#/R-DDI-1296035 Activation of Ca2+ activated Potassium channels with Intermediate conductance IEA Dictyostelium discoideum 29103 R-DDI-1296039 https://reactome.org/PathwayBrowser/#/R-DDI-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Dictyostelium discoideum 29103 R-DDI-174391 https://reactome.org/PathwayBrowser/#/R-DDI-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Dictyostelium discoideum 29103 R-DDI-2408551 https://reactome.org/PathwayBrowser/#/R-DDI-2408551 SeMet is converted to AdoSeMet by MAT IEA Dictyostelium discoideum 29103 R-DDI-2534365 https://reactome.org/PathwayBrowser/#/R-DDI-2534365 Slo3 Potassium Transport IEA Dictyostelium discoideum 29103 R-DDI-5603114 https://reactome.org/PathwayBrowser/#/R-DDI-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Dictyostelium discoideum 29103 R-DDI-70333 https://reactome.org/PathwayBrowser/#/R-DDI-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Dictyostelium discoideum 29103 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 29103 R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 29103 R-DDI-877187 https://reactome.org/PathwayBrowser/#/R-DDI-877187 P2X7 mediates loss of intracellular K+ IEA Dictyostelium discoideum 29103 R-DDI-9861616 https://reactome.org/PathwayBrowser/#/R-DDI-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 29103 R-DDI-9861667 https://reactome.org/PathwayBrowser/#/R-DDI-9861667 DLAT trimer transfers acetyl to CoA IEA Dictyostelium discoideum 29103 R-DDI-9861734 https://reactome.org/PathwayBrowser/#/R-DDI-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Dictyostelium discoideum 29103 R-DME-1013020 https://reactome.org/PathwayBrowser/#/R-DME-1013020 Activation of GIRK/Kir3 Channels IEA Drosophila melanogaster 29103 R-DME-1296024 https://reactome.org/PathwayBrowser/#/R-DME-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Drosophila melanogaster 29103 R-DME-1296035 https://reactome.org/PathwayBrowser/#/R-DME-1296035 Activation of Ca2+ activated Potassium channels with Intermediate conductance IEA Drosophila melanogaster 29103 R-DME-1296039 https://reactome.org/PathwayBrowser/#/R-DME-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Drosophila melanogaster 29103 R-DME-1296043 https://reactome.org/PathwayBrowser/#/R-DME-1296043 Activation of HCN channels IEA Drosophila melanogaster 29103 R-DME-1296045 https://reactome.org/PathwayBrowser/#/R-DME-1296045 Activation of Potassium transport channels IEA Drosophila melanogaster 29103 R-DME-1296046 https://reactome.org/PathwayBrowser/#/R-DME-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Drosophila melanogaster 29103 R-DME-1296127 https://reactome.org/PathwayBrowser/#/R-DME-1296127 Activation of voltage gated Potassium channels IEA Drosophila melanogaster 29103 R-DME-1296348 https://reactome.org/PathwayBrowser/#/R-DME-1296348 Activation of TWIK-related K+ channel (TREK) IEA Drosophila melanogaster 29103 R-DME-1299318 https://reactome.org/PathwayBrowser/#/R-DME-1299318 Activation of TASK IEA Drosophila melanogaster 29103 R-DME-1299338 https://reactome.org/PathwayBrowser/#/R-DME-1299338 Activation of TRESK IEA Drosophila melanogaster 29103 R-DME-1369017 https://reactome.org/PathwayBrowser/#/R-DME-1369017 Activation of ATP sensitive Potassium channels in muscle cells IEA Drosophila melanogaster 29103 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 29103 R-DME-204169 https://reactome.org/PathwayBrowser/#/R-DME-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Drosophila melanogaster 29103 R-DME-210404 https://reactome.org/PathwayBrowser/#/R-DME-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Drosophila melanogaster 29103 R-DME-210420 https://reactome.org/PathwayBrowser/#/R-DME-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Drosophila melanogaster 29103 R-DME-2534365 https://reactome.org/PathwayBrowser/#/R-DME-2534365 Slo3 Potassium Transport IEA Drosophila melanogaster 29103 R-DME-425678 https://reactome.org/PathwayBrowser/#/R-DME-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Drosophila melanogaster 29103 R-DME-426086 https://reactome.org/PathwayBrowser/#/R-DME-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Drosophila melanogaster 29103 R-DME-426155 https://reactome.org/PathwayBrowser/#/R-DME-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Drosophila melanogaster 29103 R-DME-428015 https://reactome.org/PathwayBrowser/#/R-DME-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29103 R-DME-5577234 https://reactome.org/PathwayBrowser/#/R-DME-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Drosophila melanogaster 29103 R-DME-5578910 https://reactome.org/PathwayBrowser/#/R-DME-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Drosophila melanogaster 29103 R-DME-5626316 https://reactome.org/PathwayBrowser/#/R-DME-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Drosophila melanogaster 29103 R-DME-5678261 https://reactome.org/PathwayBrowser/#/R-DME-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol IEA Drosophila melanogaster 29103 R-DME-70333 https://reactome.org/PathwayBrowser/#/R-DME-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Drosophila melanogaster 29103 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 29103 R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 29103 R-DME-9861616 https://reactome.org/PathwayBrowser/#/R-DME-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 29103 R-DME-9861667 https://reactome.org/PathwayBrowser/#/R-DME-9861667 DLAT trimer transfers acetyl to CoA IEA Drosophila melanogaster 29103 R-DME-9861734 https://reactome.org/PathwayBrowser/#/R-DME-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Drosophila melanogaster 29103 R-DRE-1296039 https://reactome.org/PathwayBrowser/#/R-DRE-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Danio rerio 29103 R-DRE-1296045 https://reactome.org/PathwayBrowser/#/R-DRE-1296045 Activation of Potassium transport channels IEA Danio rerio 29103 R-DRE-1296046 https://reactome.org/PathwayBrowser/#/R-DRE-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Danio rerio 29103 R-DRE-1296348 https://reactome.org/PathwayBrowser/#/R-DRE-1296348 Activation of TWIK-related K+ channel (TREK) IEA Danio rerio 29103 R-DRE-1299297 https://reactome.org/PathwayBrowser/#/R-DRE-1299297 Activation of THIK IEA Danio rerio 29103 R-DRE-1299304 https://reactome.org/PathwayBrowser/#/R-DRE-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels IEA Danio rerio 29103 R-DRE-1299338 https://reactome.org/PathwayBrowser/#/R-DRE-1299338 Activation of TRESK IEA Danio rerio 29103 R-DRE-174391 https://reactome.org/PathwayBrowser/#/R-DRE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Danio rerio 29103 R-DRE-210404 https://reactome.org/PathwayBrowser/#/R-DRE-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Danio rerio 29103 R-DRE-2408551 https://reactome.org/PathwayBrowser/#/R-DRE-2408551 SeMet is converted to AdoSeMet by MAT IEA Danio rerio 29103 R-DRE-375339 https://reactome.org/PathwayBrowser/#/R-DRE-375339 Pannexin 1/Pannexin2 mediated neuronal gap junction communication IEA Danio rerio 29103 R-DRE-375340 https://reactome.org/PathwayBrowser/#/R-DRE-375340 Connexin 62 mediated neuronal gap junction communication IEA Danio rerio 29103 R-DRE-375342 https://reactome.org/PathwayBrowser/#/R-DRE-375342 Connexin 36 mediated neuronal gap junction communication IEA Danio rerio 29103 R-DRE-426086 https://reactome.org/PathwayBrowser/#/R-DRE-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Danio rerio 29103 R-DRE-428015 https://reactome.org/PathwayBrowser/#/R-DRE-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Danio rerio 29103 R-DRE-5577234 https://reactome.org/PathwayBrowser/#/R-DRE-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Danio rerio 29103 R-DRE-5578910 https://reactome.org/PathwayBrowser/#/R-DRE-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Danio rerio 29103 R-DRE-5603114 https://reactome.org/PathwayBrowser/#/R-DRE-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Danio rerio 29103 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 29103 R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 29103 R-DRE-877187 https://reactome.org/PathwayBrowser/#/R-DRE-877187 P2X7 mediates loss of intracellular K+ IEA Danio rerio 29103 R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 29103 R-GGA-1013020 https://reactome.org/PathwayBrowser/#/R-GGA-1013020 Activation of GIRK/Kir3 Channels IEA Gallus gallus 29103 R-GGA-1296024 https://reactome.org/PathwayBrowser/#/R-GGA-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Gallus gallus 29103 R-GGA-1296037 https://reactome.org/PathwayBrowser/#/R-GGA-1296037 Activation of Ca2+ activated Potassium channels with large conductance IEA Gallus gallus 29103 R-GGA-1296039 https://reactome.org/PathwayBrowser/#/R-GGA-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Gallus gallus 29103 R-GGA-1296043 https://reactome.org/PathwayBrowser/#/R-GGA-1296043 Activation of HCN channels IEA Gallus gallus 29103 R-GGA-1296045 https://reactome.org/PathwayBrowser/#/R-GGA-1296045 Activation of Potassium transport channels IEA Gallus gallus 29103 R-GGA-1296046 https://reactome.org/PathwayBrowser/#/R-GGA-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Gallus gallus 29103 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus 29103 R-GGA-1296348 https://reactome.org/PathwayBrowser/#/R-GGA-1296348 Activation of TWIK-related K+ channel (TREK) IEA Gallus gallus 29103 R-GGA-1299297 https://reactome.org/PathwayBrowser/#/R-GGA-1299297 Activation of THIK IEA Gallus gallus 29103 R-GGA-1299304 https://reactome.org/PathwayBrowser/#/R-GGA-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels IEA Gallus gallus 29103 R-GGA-1299318 https://reactome.org/PathwayBrowser/#/R-GGA-1299318 Activation of TASK IEA Gallus gallus 29103 R-GGA-1299338 https://reactome.org/PathwayBrowser/#/R-GGA-1299338 Activation of TRESK IEA Gallus gallus 29103 R-GGA-1299359 https://reactome.org/PathwayBrowser/#/R-GGA-1299359 Activation of TALK IEA Gallus gallus 29103 R-GGA-1369017 https://reactome.org/PathwayBrowser/#/R-GGA-1369017 Activation of ATP sensitive Potassium channels in muscle cells IEA Gallus gallus 29103 R-GGA-174391 https://reactome.org/PathwayBrowser/#/R-GGA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Gallus gallus 29103 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 29103 R-GGA-204169 https://reactome.org/PathwayBrowser/#/R-GGA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Gallus gallus 29103 R-GGA-210404 https://reactome.org/PathwayBrowser/#/R-GGA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Gallus gallus 29103 R-GGA-210420 https://reactome.org/PathwayBrowser/#/R-GGA-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Gallus gallus 29103 R-GGA-2408551 https://reactome.org/PathwayBrowser/#/R-GGA-2408551 SeMet is converted to AdoSeMet by MAT IEA Gallus gallus 29103 R-GGA-2534365 https://reactome.org/PathwayBrowser/#/R-GGA-2534365 Slo3 Potassium Transport IEA Gallus gallus 29103 R-GGA-375330 https://reactome.org/PathwayBrowser/#/R-GGA-375330 Connexin 45/Connexin 36 mediated neuronal gap junction communication IEA Gallus gallus 29103 R-GGA-375339 https://reactome.org/PathwayBrowser/#/R-GGA-375339 Pannexin 1/Pannexin2 mediated neuronal gap junction communication IEA Gallus gallus 29103 R-GGA-375340 https://reactome.org/PathwayBrowser/#/R-GGA-375340 Connexin 62 mediated neuronal gap junction communication IEA Gallus gallus 29103 R-GGA-375342 https://reactome.org/PathwayBrowser/#/R-GGA-375342 Connexin 36 mediated neuronal gap junction communication IEA Gallus gallus 29103 R-GGA-425678 https://reactome.org/PathwayBrowser/#/R-GGA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Gallus gallus 29103 R-GGA-426086 https://reactome.org/PathwayBrowser/#/R-GGA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Gallus gallus 29103 R-GGA-426155 https://reactome.org/PathwayBrowser/#/R-GGA-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Gallus gallus 29103 R-GGA-428015 https://reactome.org/PathwayBrowser/#/R-GGA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Gallus gallus 29103 R-GGA-5577050 https://reactome.org/PathwayBrowser/#/R-GGA-5577050 AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region IEA Gallus gallus 29103 R-GGA-5577234 https://reactome.org/PathwayBrowser/#/R-GGA-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Gallus gallus 29103 R-GGA-5577237 https://reactome.org/PathwayBrowser/#/R-GGA-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region IEA Gallus gallus 29103 R-GGA-5578910 https://reactome.org/PathwayBrowser/#/R-GGA-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Gallus gallus 29103 R-GGA-5603114 https://reactome.org/PathwayBrowser/#/R-GGA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Gallus gallus 29103 R-GGA-5626316 https://reactome.org/PathwayBrowser/#/R-GGA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Gallus gallus 29103 R-GGA-5678261 https://reactome.org/PathwayBrowser/#/R-GGA-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol IEA Gallus gallus 29103 R-GGA-5693153 https://reactome.org/PathwayBrowser/#/R-GGA-5693153 PPM1K dephosphorylates p-BCKDH IEA Gallus gallus 29103 R-GGA-70333 https://reactome.org/PathwayBrowser/#/R-GGA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Gallus gallus 29103 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 29103 R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 29103 R-GGA-877187 https://reactome.org/PathwayBrowser/#/R-GGA-877187 P2X7 mediates loss of intracellular K+ IEA Gallus gallus 29103 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 29103 R-GGA-937311 https://reactome.org/PathwayBrowser/#/R-GGA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Gallus gallus 29103 R-GGA-9861616 https://reactome.org/PathwayBrowser/#/R-GGA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 29103 R-GGA-9861667 https://reactome.org/PathwayBrowser/#/R-GGA-9861667 DLAT trimer transfers acetyl to CoA IEA Gallus gallus 29103 R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus 29103 R-HSA-1013020 https://reactome.org/PathwayBrowser/#/R-HSA-1013020 Activation of GIRK/Kir3 Channels TAS Homo sapiens 29103 R-HSA-1296024 https://reactome.org/PathwayBrowser/#/R-HSA-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells TAS Homo sapiens 29103 R-HSA-1296035 https://reactome.org/PathwayBrowser/#/R-HSA-1296035 Activation of Ca2+ activated Potassium channels with Intermediate conductance TAS Homo sapiens 29103 R-HSA-1296037 https://reactome.org/PathwayBrowser/#/R-HSA-1296037 Activation of Ca2+ activated Potassium channels with large conductance TAS Homo sapiens 29103 R-HSA-1296039 https://reactome.org/PathwayBrowser/#/R-HSA-1296039 Activation of Ca2+ activated Potassium channels with small conductance TAS Homo sapiens 29103 R-HSA-1296043 https://reactome.org/PathwayBrowser/#/R-HSA-1296043 Activation of HCN channels TAS Homo sapiens 29103 R-HSA-1296045 https://reactome.org/PathwayBrowser/#/R-HSA-1296045 Activation of Potassium transport channels TAS Homo sapiens 29103 R-HSA-1296046 https://reactome.org/PathwayBrowser/#/R-HSA-1296046 KCNJs transport K+ from the extracellular region to cytosol TAS Homo sapiens 29103 R-HSA-1296127 https://reactome.org/PathwayBrowser/#/R-HSA-1296127 Activation of voltage gated Potassium channels TAS Homo sapiens 29103 R-HSA-1296348 https://reactome.org/PathwayBrowser/#/R-HSA-1296348 Activation of TWIK-related K+ channel (TREK) TAS Homo sapiens 29103 R-HSA-1299297 https://reactome.org/PathwayBrowser/#/R-HSA-1299297 Activation of THIK TAS Homo sapiens 29103 R-HSA-1299304 https://reactome.org/PathwayBrowser/#/R-HSA-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels TAS Homo sapiens 29103 R-HSA-1299318 https://reactome.org/PathwayBrowser/#/R-HSA-1299318 Activation of TASK TAS Homo sapiens 29103 R-HSA-1299338 https://reactome.org/PathwayBrowser/#/R-HSA-1299338 Activation of TRESK TAS Homo sapiens 29103 R-HSA-1299359 https://reactome.org/PathwayBrowser/#/R-HSA-1299359 Activation of TALK TAS Homo sapiens 29103 R-HSA-1369017 https://reactome.org/PathwayBrowser/#/R-HSA-1369017 Activation of ATP sensitive Potassium channels in muscle cells TAS Homo sapiens 29103 R-HSA-174391 https://reactome.org/PathwayBrowser/#/R-HSA-174391 MAT1A multimers transfer Ado from ATP to L-Met TAS Homo sapiens 29103 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 29103 R-HSA-204169 https://reactome.org/PathwayBrowser/#/R-HSA-204169 PDP1,2 dephosphorylate p-lipo-PDH TAS Homo sapiens 29103 R-HSA-210404 https://reactome.org/PathwayBrowser/#/R-HSA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ TAS Homo sapiens 29103 R-HSA-210420 https://reactome.org/PathwayBrowser/#/R-HSA-210420 Ca2+ influx through voltage gated Ca2+ channels TAS Homo sapiens 29103 R-HSA-2408551 https://reactome.org/PathwayBrowser/#/R-HSA-2408551 SeMet is converted to AdoSeMet by MAT TAS Homo sapiens 29103 R-HSA-2514891 https://reactome.org/PathwayBrowser/#/R-HSA-2514891 SLC24A1 exchanges 4Na+ for Ca2+, K+ IEA Homo sapiens 29103 R-HSA-2534365 https://reactome.org/PathwayBrowser/#/R-HSA-2534365 Slo3 Potassium Transport TAS Homo sapiens 29103 R-HSA-375330 https://reactome.org/PathwayBrowser/#/R-HSA-375330 Connexin 45/Connexin 36 mediated neuronal gap junction communication TAS Homo sapiens 29103 R-HSA-375339 https://reactome.org/PathwayBrowser/#/R-HSA-375339 Pannexin 1/Pannexin2 mediated neuronal gap junction communication TAS Homo sapiens 29103 R-HSA-375340 https://reactome.org/PathwayBrowser/#/R-HSA-375340 Connexin 62 mediated neuronal gap junction communication TAS Homo sapiens 29103 R-HSA-375342 https://reactome.org/PathwayBrowser/#/R-HSA-375342 Connexin 36 mediated neuronal gap junction communication TAS Homo sapiens 29103 R-HSA-425678 https://reactome.org/PathwayBrowser/#/R-HSA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ TAS Homo sapiens 29103 R-HSA-426086 https://reactome.org/PathwayBrowser/#/R-HSA-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol TAS Homo sapiens 29103 R-HSA-426155 https://reactome.org/PathwayBrowser/#/R-HSA-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region TAS Homo sapiens 29103 R-HSA-428015 https://reactome.org/PathwayBrowser/#/R-HSA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29103 R-HSA-5577050 https://reactome.org/PathwayBrowser/#/R-HSA-5577050 AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region TAS Homo sapiens 29103 R-HSA-5577234 https://reactome.org/PathwayBrowser/#/R-HSA-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region TAS Homo sapiens 29103 R-HSA-5577237 https://reactome.org/PathwayBrowser/#/R-HSA-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region TAS Homo sapiens 29103 R-HSA-5578910 https://reactome.org/PathwayBrowser/#/R-HSA-5578910 KCNK dimers transport K+ from cytosol to extracellular region TAS Homo sapiens 29103 R-HSA-5603087 https://reactome.org/PathwayBrowser/#/R-HSA-5603087 Defective MAT1A does not transfer Ado from ATP to L-Met TAS Homo sapiens 29103 R-HSA-5603114 https://reactome.org/PathwayBrowser/#/R-HSA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met TAS Homo sapiens 29103 R-HSA-5623588 https://reactome.org/PathwayBrowser/#/R-HSA-5623588 Defective SLC12A1 does not cotransport Na+, K+, 2Cl- from extracellular region to cytosol TAS Homo sapiens 29103 R-HSA-5623806 https://reactome.org/PathwayBrowser/#/R-HSA-5623806 Defective SLC12A6 does not cotransport K+, Cl- from cytosol to extracellular region TAS Homo sapiens 29103 R-HSA-5625015 https://reactome.org/PathwayBrowser/#/R-HSA-5625015 Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29103 R-HSA-5625029 https://reactome.org/PathwayBrowser/#/R-HSA-5625029 SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29103 R-HSA-5625841 https://reactome.org/PathwayBrowser/#/R-HSA-5625841 Defective SLC24A1 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ TAS Homo sapiens 29103 R-HSA-5626270 https://reactome.org/PathwayBrowser/#/R-HSA-5626270 Defective SLC24A4 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ TAS Homo sapiens 29103 R-HSA-5626316 https://reactome.org/PathwayBrowser/#/R-HSA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ TAS Homo sapiens 29103 R-HSA-5626356 https://reactome.org/PathwayBrowser/#/R-HSA-5626356 Defective SLC24A5 does not exchange cytosolic 4Na+ for Golgi luminal Ca2+, K+ TAS Homo sapiens 29103 R-HSA-5678261 https://reactome.org/PathwayBrowser/#/R-HSA-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol TAS Homo sapiens 29103 R-HSA-5678418 https://reactome.org/PathwayBrowser/#/R-HSA-5678418 Defective ABCC9 (in KCNJ11:ABCC9) does not transport K+ from extracellular region to cytosol TAS Homo sapiens 29103 R-HSA-5683209 https://reactome.org/PathwayBrowser/#/R-HSA-5683209 Activating ABCC8 mutants cause hyperglycemia in permanent neonatal diabetes mellitus (PNDM) and transient neonatal DM (TNDM). TAS Homo sapiens 29103 R-HSA-5693148 https://reactome.org/PathwayBrowser/#/R-HSA-5693148 BCKDK phosphorylates BCKDH TAS Homo sapiens 29103 R-HSA-5693153 https://reactome.org/PathwayBrowser/#/R-HSA-5693153 PPM1K dephosphorylates p-BCKDH TAS Homo sapiens 29103 R-HSA-70333 https://reactome.org/PathwayBrowser/#/R-HSA-70333 KHK dimer phosphorylates Fru to Fru 1-P TAS Homo sapiens 29103 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 29103 R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 29103 R-HSA-877187 https://reactome.org/PathwayBrowser/#/R-HSA-877187 P2X7 mediates loss of intracellular K+ TAS Homo sapiens 29103 R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 29103 R-HSA-937311 https://reactome.org/PathwayBrowser/#/R-HSA-937311 ATP12A:ATP4B exchanges K+ for H+ TAS Homo sapiens 29103 R-HSA-9648983 https://reactome.org/PathwayBrowser/#/R-HSA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ TAS Homo sapiens 29103 R-HSA-9659380 https://reactome.org/PathwayBrowser/#/R-HSA-9659380 Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell IEA Homo sapiens 29103 R-HSA-9659515 https://reactome.org/PathwayBrowser/#/R-HSA-9659515 CACNA1D:CACNA2D2:CACNB2 (Cav1.3 channel) transports Ca2+ into the cytosol of an inner hair cell IEA Homo sapiens 29103 R-HSA-9659554 https://reactome.org/PathwayBrowser/#/R-HSA-9659554 KCNQ4 transports K+ from the cytosol to the extracellular region IEA Homo sapiens 29103 R-HSA-9663354 https://reactome.org/PathwayBrowser/#/R-HSA-9663354 SLC26A5 (prestin) changes conformation in response to depolarization IEA Homo sapiens 29103 R-HSA-9663363 https://reactome.org/PathwayBrowser/#/R-HSA-9663363 Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell IEA Homo sapiens 29103 R-HSA-9663752 https://reactome.org/PathwayBrowser/#/R-HSA-9663752 KCNN2 transports K+ from the cytosol to the extracellular region IEA Homo sapiens 29103 R-HSA-9667761 https://reactome.org/PathwayBrowser/#/R-HSA-9667761 KCNMA1:KCNMB1:LRRC52 transports K+ from the cytosol to the extracellular region IEA Homo sapiens 29103 R-HSA-9667809 https://reactome.org/PathwayBrowser/#/R-HSA-9667809 KCNMA1:KCNMB1 transports potassium ions from the cytosol to the extracellular region IEA Homo sapiens 29103 R-HSA-9727198 https://reactome.org/PathwayBrowser/#/R-HSA-9727198 ATP4A:ATP4B exchanges K+ for H+ TAS Homo sapiens 29103 R-HSA-9729870 https://reactome.org/PathwayBrowser/#/R-HSA-9729870 KCNJ2 (KIR2.1) transports K+ from the extracellular region to the cytosol IEA Homo sapiens 29103 R-HSA-9730521 https://reactome.org/PathwayBrowser/#/R-HSA-9730521 SARS-CoV-2 3a induces potassium efflux TAS Homo sapiens 29103 R-HSA-9731072 https://reactome.org/PathwayBrowser/#/R-HSA-9731072 SARS-CoV-1 3a tetramer induces potassium efflux TAS Homo sapiens 29103 R-HSA-975311 https://reactome.org/PathwayBrowser/#/R-HSA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ TAS Homo sapiens 29103 R-HSA-9837835 https://reactome.org/PathwayBrowser/#/R-HSA-9837835 SH pentamer transports K+ TAS Homo sapiens 29103 R-HSA-9861616 https://reactome.org/PathwayBrowser/#/R-HSA-9861616 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 29103 R-HSA-9861667 https://reactome.org/PathwayBrowser/#/R-HSA-9861667 DLAT trimer transfers acetyl to CoA TAS Homo sapiens 29103 R-HSA-9861734 https://reactome.org/PathwayBrowser/#/R-HSA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT TAS Homo sapiens 29103 R-MMU-1013020 https://reactome.org/PathwayBrowser/#/R-MMU-1013020 Activation of GIRK/Kir3 Channels IEA Mus musculus 29103 R-MMU-1296024 https://reactome.org/PathwayBrowser/#/R-MMU-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Mus musculus 29103 R-MMU-1296035 https://reactome.org/PathwayBrowser/#/R-MMU-1296035 Activation of Ca2+ activated Potassium channels with Intermediate conductance IEA Mus musculus 29103 R-MMU-1296037 https://reactome.org/PathwayBrowser/#/R-MMU-1296037 Activation of Ca2+ activated Potassium channels with large conductance IEA Mus musculus 29103 R-MMU-1296039 https://reactome.org/PathwayBrowser/#/R-MMU-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Mus musculus 29103 R-MMU-1296043 https://reactome.org/PathwayBrowser/#/R-MMU-1296043 Activation of HCN channels IEA Mus musculus 29103 R-MMU-1296045 https://reactome.org/PathwayBrowser/#/R-MMU-1296045 Activation of Potassium transport channels IEA Mus musculus 29103 R-MMU-1296046 https://reactome.org/PathwayBrowser/#/R-MMU-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Mus musculus 29103 R-MMU-1296127 https://reactome.org/PathwayBrowser/#/R-MMU-1296127 Activation of voltage gated Potassium channels IEA Mus musculus 29103 R-MMU-1296348 https://reactome.org/PathwayBrowser/#/R-MMU-1296348 Activation of TWIK-related K+ channel (TREK) IEA Mus musculus 29103 R-MMU-1299297 https://reactome.org/PathwayBrowser/#/R-MMU-1299297 Activation of THIK IEA Mus musculus 29103 R-MMU-1299304 https://reactome.org/PathwayBrowser/#/R-MMU-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels IEA Mus musculus 29103 R-MMU-1299318 https://reactome.org/PathwayBrowser/#/R-MMU-1299318 Activation of TASK IEA Mus musculus 29103 R-MMU-1299338 https://reactome.org/PathwayBrowser/#/R-MMU-1299338 Activation of TRESK IEA Mus musculus 29103 R-MMU-1299359 https://reactome.org/PathwayBrowser/#/R-MMU-1299359 Activation of TALK IEA Mus musculus 29103 R-MMU-1369017 https://reactome.org/PathwayBrowser/#/R-MMU-1369017 Activation of ATP sensitive Potassium channels in muscle cells IEA Mus musculus 29103 R-MMU-174391 https://reactome.org/PathwayBrowser/#/R-MMU-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Mus musculus 29103 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 29103 R-MMU-204169 https://reactome.org/PathwayBrowser/#/R-MMU-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Mus musculus 29103 R-MMU-210404 https://reactome.org/PathwayBrowser/#/R-MMU-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Mus musculus 29103 R-MMU-210420 https://reactome.org/PathwayBrowser/#/R-MMU-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Mus musculus 29103 R-MMU-2408551 https://reactome.org/PathwayBrowser/#/R-MMU-2408551 SeMet is converted to AdoSeMet by MAT IEA Mus musculus 29103 R-MMU-2534365 https://reactome.org/PathwayBrowser/#/R-MMU-2534365 Slo3 Potassium Transport IEA Mus musculus 29103 R-MMU-375330 https://reactome.org/PathwayBrowser/#/R-MMU-375330 Connexin 45/Connexin 36 mediated neuronal gap junction communication IEA Mus musculus 29103 R-MMU-375339 https://reactome.org/PathwayBrowser/#/R-MMU-375339 Pannexin 1/Pannexin2 mediated neuronal gap junction communication IEA Mus musculus 29103 R-MMU-375340 https://reactome.org/PathwayBrowser/#/R-MMU-375340 Connexin 62 mediated neuronal gap junction communication IEA Mus musculus 29103 R-MMU-375342 https://reactome.org/PathwayBrowser/#/R-MMU-375342 Connexin 36 mediated neuronal gap junction communication IEA Mus musculus 29103 R-MMU-425678 https://reactome.org/PathwayBrowser/#/R-MMU-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Mus musculus 29103 R-MMU-426086 https://reactome.org/PathwayBrowser/#/R-MMU-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Mus musculus 29103 R-MMU-426155 https://reactome.org/PathwayBrowser/#/R-MMU-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Mus musculus 29103 R-MMU-428015 https://reactome.org/PathwayBrowser/#/R-MMU-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Mus musculus 29103 R-MMU-5577050 https://reactome.org/PathwayBrowser/#/R-MMU-5577050 AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region IEA Mus musculus 29103 R-MMU-5577234 https://reactome.org/PathwayBrowser/#/R-MMU-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Mus musculus 29103 R-MMU-5577237 https://reactome.org/PathwayBrowser/#/R-MMU-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region IEA Mus musculus 29103 R-MMU-5578910 https://reactome.org/PathwayBrowser/#/R-MMU-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Mus musculus 29103 R-MMU-5603114 https://reactome.org/PathwayBrowser/#/R-MMU-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Mus musculus 29103 R-MMU-5626316 https://reactome.org/PathwayBrowser/#/R-MMU-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Mus musculus 29103 R-MMU-5678261 https://reactome.org/PathwayBrowser/#/R-MMU-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol IEA Mus musculus 29103 R-MMU-5693148 https://reactome.org/PathwayBrowser/#/R-MMU-5693148 BCKDK phosphorylates BCKDH IEA Mus musculus 29103 R-MMU-5693153 https://reactome.org/PathwayBrowser/#/R-MMU-5693153 PPM1K dephosphorylates p-BCKDH IEA Mus musculus 29103 R-MMU-70333 https://reactome.org/PathwayBrowser/#/R-MMU-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Mus musculus 29103 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 29103 R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 29103 R-MMU-877187 https://reactome.org/PathwayBrowser/#/R-MMU-877187 P2X7 mediates loss of intracellular K+ IEA Mus musculus 29103 R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 29103 R-MMU-937311 https://reactome.org/PathwayBrowser/#/R-MMU-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Mus musculus 29103 R-MMU-9648983 https://reactome.org/PathwayBrowser/#/R-MMU-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Mus musculus 29103 R-MMU-9659489 https://reactome.org/PathwayBrowser/#/R-MMU-9659489 Cacna1d:Cacna2d2:Cacnb2 (Cav1.3 channel) transports calcium into the cytosol of an inner hair cell TAS Mus musculus 29103 R-MMU-9659536 https://reactome.org/PathwayBrowser/#/R-MMU-9659536 MET channel transports cations from the extracellular region into the cytosol of stereocilia of cochlear inner hair cell TAS Mus musculus 29103 R-MMU-9659557 https://reactome.org/PathwayBrowser/#/R-MMU-9659557 Kcnq4 transports K+ from the cytosol to the extracellular region TAS Mus musculus 29103 R-MMU-9663360 https://reactome.org/PathwayBrowser/#/R-MMU-9663360 MET channel transports cations from the extracellular region into the cytosol of stereocilia of cochlear outer hair cell TAS Mus musculus 29103 R-MMU-9663768 https://reactome.org/PathwayBrowser/#/R-MMU-9663768 Kcnn2 transports K+ from the cytosol to the extracellular region TAS Mus musculus 29103 R-MMU-9667756 https://reactome.org/PathwayBrowser/#/R-MMU-9667756 Kcnma1:Kcnmb1:Lrrc52 transports potassium ions from the cytosol to the extracellular region TAS Mus musculus 29103 R-MMU-9667762 https://reactome.org/PathwayBrowser/#/R-MMU-9667762 Kcnma1:Kcnmb1 transport potassium ions from the cytosol to the extracellular region TAS Mus musculus 29103 R-MMU-9727198 https://reactome.org/PathwayBrowser/#/R-MMU-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Mus musculus 29103 R-MMU-9729881 https://reactome.org/PathwayBrowser/#/R-MMU-9729881 Kcnj2 transports K+ from the extracellular region to the cytosol TAS Mus musculus 29103 R-MMU-975311 https://reactome.org/PathwayBrowser/#/R-MMU-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Mus musculus 29103 R-MMU-9861616 https://reactome.org/PathwayBrowser/#/R-MMU-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 29103 R-MMU-9861667 https://reactome.org/PathwayBrowser/#/R-MMU-9861667 DLAT trimer transfers acetyl to CoA IEA Mus musculus 29103 R-MMU-9861734 https://reactome.org/PathwayBrowser/#/R-MMU-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Mus musculus 29103 R-PFA-174391 https://reactome.org/PathwayBrowser/#/R-PFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Plasmodium falciparum 29103 R-PFA-2408551 https://reactome.org/PathwayBrowser/#/R-PFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Plasmodium falciparum 29103 R-PFA-2534365 https://reactome.org/PathwayBrowser/#/R-PFA-2534365 Slo3 Potassium Transport IEA Plasmodium falciparum 29103 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 29103 R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 29103 R-RNO-1013020 https://reactome.org/PathwayBrowser/#/R-RNO-1013020 Activation of GIRK/Kir3 Channels IEA Rattus norvegicus 29103 R-RNO-1296024 https://reactome.org/PathwayBrowser/#/R-RNO-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Rattus norvegicus 29103 R-RNO-1296035 https://reactome.org/PathwayBrowser/#/R-RNO-1296035 Activation of Ca2+ activated Potassium channels with Intermediate conductance IEA Rattus norvegicus 29103 R-RNO-1296037 https://reactome.org/PathwayBrowser/#/R-RNO-1296037 Activation of Ca2+ activated Potassium channels with large conductance IEA Rattus norvegicus 29103 R-RNO-1296039 https://reactome.org/PathwayBrowser/#/R-RNO-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Rattus norvegicus 29103 R-RNO-1296043 https://reactome.org/PathwayBrowser/#/R-RNO-1296043 Activation of HCN channels IEA Rattus norvegicus 29103 R-RNO-1296045 https://reactome.org/PathwayBrowser/#/R-RNO-1296045 Activation of Potassium transport channels IEA Rattus norvegicus 29103 R-RNO-1296046 https://reactome.org/PathwayBrowser/#/R-RNO-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Rattus norvegicus 29103 R-RNO-1296127 https://reactome.org/PathwayBrowser/#/R-RNO-1296127 Activation of voltage gated Potassium channels IEA Rattus norvegicus 29103 R-RNO-1296348 https://reactome.org/PathwayBrowser/#/R-RNO-1296348 Activation of TWIK-related K+ channel (TREK) IEA Rattus norvegicus 29103 R-RNO-1299297 https://reactome.org/PathwayBrowser/#/R-RNO-1299297 Activation of THIK IEA Rattus norvegicus 29103 R-RNO-1299304 https://reactome.org/PathwayBrowser/#/R-RNO-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels IEA Rattus norvegicus 29103 R-RNO-1299318 https://reactome.org/PathwayBrowser/#/R-RNO-1299318 Activation of TASK IEA Rattus norvegicus 29103 R-RNO-1299338 https://reactome.org/PathwayBrowser/#/R-RNO-1299338 Activation of TRESK IEA Rattus norvegicus 29103 R-RNO-1299359 https://reactome.org/PathwayBrowser/#/R-RNO-1299359 Activation of TALK IEA Rattus norvegicus 29103 R-RNO-1369017 https://reactome.org/PathwayBrowser/#/R-RNO-1369017 Activation of ATP sensitive Potassium channels in muscle cells IEA Rattus norvegicus 29103 R-RNO-174391 https://reactome.org/PathwayBrowser/#/R-RNO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Rattus norvegicus 29103 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 29103 R-RNO-204169 https://reactome.org/PathwayBrowser/#/R-RNO-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Rattus norvegicus 29103 R-RNO-210404 https://reactome.org/PathwayBrowser/#/R-RNO-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Rattus norvegicus 29103 R-RNO-210420 https://reactome.org/PathwayBrowser/#/R-RNO-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Rattus norvegicus 29103 R-RNO-2408551 https://reactome.org/PathwayBrowser/#/R-RNO-2408551 SeMet is converted to AdoSeMet by MAT IEA Rattus norvegicus 29103 R-RNO-2534365 https://reactome.org/PathwayBrowser/#/R-RNO-2534365 Slo3 Potassium Transport IEA Rattus norvegicus 29103 R-RNO-375330 https://reactome.org/PathwayBrowser/#/R-RNO-375330 Connexin 45/Connexin 36 mediated neuronal gap junction communication IEA Rattus norvegicus 29103 R-RNO-375339 https://reactome.org/PathwayBrowser/#/R-RNO-375339 Pannexin 1/Pannexin2 mediated neuronal gap junction communication IEA Rattus norvegicus 29103 R-RNO-375340 https://reactome.org/PathwayBrowser/#/R-RNO-375340 Connexin 62 mediated neuronal gap junction communication IEA Rattus norvegicus 29103 R-RNO-375342 https://reactome.org/PathwayBrowser/#/R-RNO-375342 Connexin 36 mediated neuronal gap junction communication IEA Rattus norvegicus 29103 R-RNO-425678 https://reactome.org/PathwayBrowser/#/R-RNO-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Rattus norvegicus 29103 R-RNO-426086 https://reactome.org/PathwayBrowser/#/R-RNO-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Rattus norvegicus 29103 R-RNO-426155 https://reactome.org/PathwayBrowser/#/R-RNO-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Rattus norvegicus 29103 R-RNO-428015 https://reactome.org/PathwayBrowser/#/R-RNO-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Rattus norvegicus 29103 R-RNO-5577050 https://reactome.org/PathwayBrowser/#/R-RNO-5577050 AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region IEA Rattus norvegicus 29103 R-RNO-5577234 https://reactome.org/PathwayBrowser/#/R-RNO-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Rattus norvegicus 29103 R-RNO-5577237 https://reactome.org/PathwayBrowser/#/R-RNO-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region IEA Rattus norvegicus 29103 R-RNO-5578910 https://reactome.org/PathwayBrowser/#/R-RNO-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Rattus norvegicus 29103 R-RNO-5603114 https://reactome.org/PathwayBrowser/#/R-RNO-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Rattus norvegicus 29103 R-RNO-5626316 https://reactome.org/PathwayBrowser/#/R-RNO-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Rattus norvegicus 29103 R-RNO-5678261 https://reactome.org/PathwayBrowser/#/R-RNO-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol IEA Rattus norvegicus 29103 R-RNO-5693148 https://reactome.org/PathwayBrowser/#/R-RNO-5693148 BCKDK phosphorylates BCKDH IEA Rattus norvegicus 29103 R-RNO-5693153 https://reactome.org/PathwayBrowser/#/R-RNO-5693153 PPM1K dephosphorylates p-BCKDH IEA Rattus norvegicus 29103 R-RNO-70333 https://reactome.org/PathwayBrowser/#/R-RNO-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Rattus norvegicus 29103 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 29103 R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 29103 R-RNO-877187 https://reactome.org/PathwayBrowser/#/R-RNO-877187 P2X7 mediates loss of intracellular K+ IEA Rattus norvegicus 29103 R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 29103 R-RNO-937311 https://reactome.org/PathwayBrowser/#/R-RNO-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 29103 R-RNO-9648983 https://reactome.org/PathwayBrowser/#/R-RNO-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Rattus norvegicus 29103 R-RNO-9665067 https://reactome.org/PathwayBrowser/#/R-RNO-9665067 MET channel transports cations from the extracellular region into the cytosol of stereocilia TAS Rattus norvegicus 29103 R-RNO-9667806 https://reactome.org/PathwayBrowser/#/R-RNO-9667806 Kcnma1:Kcnmb1 transports potassium ions from the cytosol to the extracellular region TAS Rattus norvegicus 29103 R-RNO-9727198 https://reactome.org/PathwayBrowser/#/R-RNO-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 29103 R-RNO-975311 https://reactome.org/PathwayBrowser/#/R-RNO-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Rattus norvegicus 29103 R-RNO-9861616 https://reactome.org/PathwayBrowser/#/R-RNO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 29103 R-RNO-9861667 https://reactome.org/PathwayBrowser/#/R-RNO-9861667 DLAT trimer transfers acetyl to CoA IEA Rattus norvegicus 29103 R-RNO-9861734 https://reactome.org/PathwayBrowser/#/R-RNO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Rattus norvegicus 29103 R-SCE-1296348 https://reactome.org/PathwayBrowser/#/R-SCE-1296348 Activation of TWIK-related K+ channel (TREK) IEA Saccharomyces cerevisiae 29103 R-SCE-1299297 https://reactome.org/PathwayBrowser/#/R-SCE-1299297 Activation of THIK IEA Saccharomyces cerevisiae 29103 R-SCE-1299304 https://reactome.org/PathwayBrowser/#/R-SCE-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels IEA Saccharomyces cerevisiae 29103 R-SCE-1299318 https://reactome.org/PathwayBrowser/#/R-SCE-1299318 Activation of TASK IEA Saccharomyces cerevisiae 29103 R-SCE-1299338 https://reactome.org/PathwayBrowser/#/R-SCE-1299338 Activation of TRESK IEA Saccharomyces cerevisiae 29103 R-SCE-1299359 https://reactome.org/PathwayBrowser/#/R-SCE-1299359 Activation of TALK IEA Saccharomyces cerevisiae 29103 R-SCE-174391 https://reactome.org/PathwayBrowser/#/R-SCE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Saccharomyces cerevisiae 29103 R-SCE-2408551 https://reactome.org/PathwayBrowser/#/R-SCE-2408551 SeMet is converted to AdoSeMet by MAT IEA Saccharomyces cerevisiae 29103 R-SCE-5578910 https://reactome.org/PathwayBrowser/#/R-SCE-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Saccharomyces cerevisiae 29103 R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 29103 R-SCE-9861616 https://reactome.org/PathwayBrowser/#/R-SCE-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 29103 R-SCE-9861667 https://reactome.org/PathwayBrowser/#/R-SCE-9861667 DLAT trimer transfers acetyl to CoA IEA Saccharomyces cerevisiae 29103 R-SCE-9861734 https://reactome.org/PathwayBrowser/#/R-SCE-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Saccharomyces cerevisiae 29103 R-SPO-174391 https://reactome.org/PathwayBrowser/#/R-SPO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Schizosaccharomyces pombe 29103 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 29103 R-SPO-2408551 https://reactome.org/PathwayBrowser/#/R-SPO-2408551 SeMet is converted to AdoSeMet by MAT IEA Schizosaccharomyces pombe 29103 R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 29103 R-SPO-9861616 https://reactome.org/PathwayBrowser/#/R-SPO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 29103 R-SPO-9861667 https://reactome.org/PathwayBrowser/#/R-SPO-9861667 DLAT trimer transfers acetyl to CoA IEA Schizosaccharomyces pombe 29103 R-SPO-9861734 https://reactome.org/PathwayBrowser/#/R-SPO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Schizosaccharomyces pombe 29103 R-SSC-1013020 https://reactome.org/PathwayBrowser/#/R-SSC-1013020 Activation of GIRK/Kir3 Channels IEA Sus scrofa 29103 R-SSC-1296024 https://reactome.org/PathwayBrowser/#/R-SSC-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Sus scrofa 29103 R-SSC-1296035 https://reactome.org/PathwayBrowser/#/R-SSC-1296035 Activation of Ca2+ activated Potassium channels with Intermediate conductance IEA Sus scrofa 29103 R-SSC-1296037 https://reactome.org/PathwayBrowser/#/R-SSC-1296037 Activation of Ca2+ activated Potassium channels with large conductance IEA Sus scrofa 29103 R-SSC-1296039 https://reactome.org/PathwayBrowser/#/R-SSC-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Sus scrofa 29103 R-SSC-1296043 https://reactome.org/PathwayBrowser/#/R-SSC-1296043 Activation of HCN channels IEA Sus scrofa 29103 R-SSC-1296045 https://reactome.org/PathwayBrowser/#/R-SSC-1296045 Activation of Potassium transport channels IEA Sus scrofa 29103 R-SSC-1296046 https://reactome.org/PathwayBrowser/#/R-SSC-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Sus scrofa 29103 R-SSC-1296127 https://reactome.org/PathwayBrowser/#/R-SSC-1296127 Activation of voltage gated Potassium channels IEA Sus scrofa 29103 R-SSC-1296348 https://reactome.org/PathwayBrowser/#/R-SSC-1296348 Activation of TWIK-related K+ channel (TREK) IEA Sus scrofa 29103 R-SSC-1299297 https://reactome.org/PathwayBrowser/#/R-SSC-1299297 Activation of THIK IEA Sus scrofa 29103 R-SSC-1299304 https://reactome.org/PathwayBrowser/#/R-SSC-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels IEA Sus scrofa 29103 R-SSC-1299318 https://reactome.org/PathwayBrowser/#/R-SSC-1299318 Activation of TASK IEA Sus scrofa 29103 R-SSC-1299359 https://reactome.org/PathwayBrowser/#/R-SSC-1299359 Activation of TALK IEA Sus scrofa 29103 R-SSC-1369017 https://reactome.org/PathwayBrowser/#/R-SSC-1369017 Activation of ATP sensitive Potassium channels in muscle cells IEA Sus scrofa 29103 R-SSC-174391 https://reactome.org/PathwayBrowser/#/R-SSC-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Sus scrofa 29103 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 29103 R-SSC-204169 https://reactome.org/PathwayBrowser/#/R-SSC-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Sus scrofa 29103 R-SSC-210404 https://reactome.org/PathwayBrowser/#/R-SSC-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Sus scrofa 29103 R-SSC-210420 https://reactome.org/PathwayBrowser/#/R-SSC-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Sus scrofa 29103 R-SSC-2408551 https://reactome.org/PathwayBrowser/#/R-SSC-2408551 SeMet is converted to AdoSeMet by MAT IEA Sus scrofa 29103 R-SSC-2534365 https://reactome.org/PathwayBrowser/#/R-SSC-2534365 Slo3 Potassium Transport IEA Sus scrofa 29103 R-SSC-375330 https://reactome.org/PathwayBrowser/#/R-SSC-375330 Connexin 45/Connexin 36 mediated neuronal gap junction communication IEA Sus scrofa 29103 R-SSC-375339 https://reactome.org/PathwayBrowser/#/R-SSC-375339 Pannexin 1/Pannexin2 mediated neuronal gap junction communication IEA Sus scrofa 29103 R-SSC-375340 https://reactome.org/PathwayBrowser/#/R-SSC-375340 Connexin 62 mediated neuronal gap junction communication IEA Sus scrofa 29103 R-SSC-375342 https://reactome.org/PathwayBrowser/#/R-SSC-375342 Connexin 36 mediated neuronal gap junction communication IEA Sus scrofa 29103 R-SSC-425678 https://reactome.org/PathwayBrowser/#/R-SSC-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Sus scrofa 29103 R-SSC-426086 https://reactome.org/PathwayBrowser/#/R-SSC-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Sus scrofa 29103 R-SSC-426155 https://reactome.org/PathwayBrowser/#/R-SSC-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Sus scrofa 29103 R-SSC-428015 https://reactome.org/PathwayBrowser/#/R-SSC-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Sus scrofa 29103 R-SSC-5577234 https://reactome.org/PathwayBrowser/#/R-SSC-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Sus scrofa 29103 R-SSC-5577237 https://reactome.org/PathwayBrowser/#/R-SSC-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region IEA Sus scrofa 29103 R-SSC-5578910 https://reactome.org/PathwayBrowser/#/R-SSC-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Sus scrofa 29103 R-SSC-5603114 https://reactome.org/PathwayBrowser/#/R-SSC-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Sus scrofa 29103 R-SSC-5626316 https://reactome.org/PathwayBrowser/#/R-SSC-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Sus scrofa 29103 R-SSC-5678261 https://reactome.org/PathwayBrowser/#/R-SSC-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol IEA Sus scrofa 29103 R-SSC-5693148 https://reactome.org/PathwayBrowser/#/R-SSC-5693148 BCKDK phosphorylates BCKDH IEA Sus scrofa 29103 R-SSC-5693153 https://reactome.org/PathwayBrowser/#/R-SSC-5693153 PPM1K dephosphorylates p-BCKDH IEA Sus scrofa 29103 R-SSC-70333 https://reactome.org/PathwayBrowser/#/R-SSC-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Sus scrofa 29103 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 29103 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 29103 R-SSC-877187 https://reactome.org/PathwayBrowser/#/R-SSC-877187 P2X7 mediates loss of intracellular K+ IEA Sus scrofa 29103 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 29103 R-SSC-937311 https://reactome.org/PathwayBrowser/#/R-SSC-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Sus scrofa 29103 R-SSC-9648983 https://reactome.org/PathwayBrowser/#/R-SSC-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Sus scrofa 29103 R-SSC-9727198 https://reactome.org/PathwayBrowser/#/R-SSC-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Sus scrofa 29103 R-SSC-975311 https://reactome.org/PathwayBrowser/#/R-SSC-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Sus scrofa 29103 R-SSC-9861616 https://reactome.org/PathwayBrowser/#/R-SSC-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 29103 R-SSC-9861667 https://reactome.org/PathwayBrowser/#/R-SSC-9861667 DLAT trimer transfers acetyl to CoA IEA Sus scrofa 29103 R-SSC-9861734 https://reactome.org/PathwayBrowser/#/R-SSC-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Sus scrofa 29103 R-XTR-1013020 https://reactome.org/PathwayBrowser/#/R-XTR-1013020 Activation of GIRK/Kir3 Channels IEA Xenopus tropicalis 29103 R-XTR-1296024 https://reactome.org/PathwayBrowser/#/R-XTR-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Xenopus tropicalis 29103 R-XTR-1296035 https://reactome.org/PathwayBrowser/#/R-XTR-1296035 Activation of Ca2+ activated Potassium channels with Intermediate conductance IEA Xenopus tropicalis 29103 R-XTR-1296039 https://reactome.org/PathwayBrowser/#/R-XTR-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Xenopus tropicalis 29103 R-XTR-1296043 https://reactome.org/PathwayBrowser/#/R-XTR-1296043 Activation of HCN channels IEA Xenopus tropicalis 29103 R-XTR-1296045 https://reactome.org/PathwayBrowser/#/R-XTR-1296045 Activation of Potassium transport channels IEA Xenopus tropicalis 29103 R-XTR-1296046 https://reactome.org/PathwayBrowser/#/R-XTR-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Xenopus tropicalis 29103 R-XTR-1296127 https://reactome.org/PathwayBrowser/#/R-XTR-1296127 Activation of voltage gated Potassium channels IEA Xenopus tropicalis 29103 R-XTR-1296348 https://reactome.org/PathwayBrowser/#/R-XTR-1296348 Activation of TWIK-related K+ channel (TREK) IEA Xenopus tropicalis 29103 R-XTR-1299304 https://reactome.org/PathwayBrowser/#/R-XTR-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels IEA Xenopus tropicalis 29103 R-XTR-1299318 https://reactome.org/PathwayBrowser/#/R-XTR-1299318 Activation of TASK IEA Xenopus tropicalis 29103 R-XTR-1299338 https://reactome.org/PathwayBrowser/#/R-XTR-1299338 Activation of TRESK IEA Xenopus tropicalis 29103 R-XTR-1299359 https://reactome.org/PathwayBrowser/#/R-XTR-1299359 Activation of TALK IEA Xenopus tropicalis 29103 R-XTR-1369017 https://reactome.org/PathwayBrowser/#/R-XTR-1369017 Activation of ATP sensitive Potassium channels in muscle cells IEA Xenopus tropicalis 29103 R-XTR-174391 https://reactome.org/PathwayBrowser/#/R-XTR-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Xenopus tropicalis 29103 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 29103 R-XTR-210404 https://reactome.org/PathwayBrowser/#/R-XTR-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Xenopus tropicalis 29103 R-XTR-2408551 https://reactome.org/PathwayBrowser/#/R-XTR-2408551 SeMet is converted to AdoSeMet by MAT IEA Xenopus tropicalis 29103 R-XTR-375330 https://reactome.org/PathwayBrowser/#/R-XTR-375330 Connexin 45/Connexin 36 mediated neuronal gap junction communication IEA Xenopus tropicalis 29103 R-XTR-375342 https://reactome.org/PathwayBrowser/#/R-XTR-375342 Connexin 36 mediated neuronal gap junction communication IEA Xenopus tropicalis 29103 R-XTR-425678 https://reactome.org/PathwayBrowser/#/R-XTR-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Xenopus tropicalis 29103 R-XTR-426086 https://reactome.org/PathwayBrowser/#/R-XTR-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Xenopus tropicalis 29103 R-XTR-426155 https://reactome.org/PathwayBrowser/#/R-XTR-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Xenopus tropicalis 29103 R-XTR-428015 https://reactome.org/PathwayBrowser/#/R-XTR-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29103 R-XTR-5577234 https://reactome.org/PathwayBrowser/#/R-XTR-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Xenopus tropicalis 29103 R-XTR-5578910 https://reactome.org/PathwayBrowser/#/R-XTR-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Xenopus tropicalis 29103 R-XTR-5603114 https://reactome.org/PathwayBrowser/#/R-XTR-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Xenopus tropicalis 29103 R-XTR-5626316 https://reactome.org/PathwayBrowser/#/R-XTR-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Xenopus tropicalis 29103 R-XTR-5678261 https://reactome.org/PathwayBrowser/#/R-XTR-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol IEA Xenopus tropicalis 29103 R-XTR-5693148 https://reactome.org/PathwayBrowser/#/R-XTR-5693148 BCKDK phosphorylates BCKDH IEA Xenopus tropicalis 29103 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 29103 R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 29103 R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 29103 R-XTR-937311 https://reactome.org/PathwayBrowser/#/R-XTR-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 29103 R-XTR-9727198 https://reactome.org/PathwayBrowser/#/R-XTR-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 29103 R-XTR-9861616 https://reactome.org/PathwayBrowser/#/R-XTR-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 29103 R-XTR-9861667 https://reactome.org/PathwayBrowser/#/R-XTR-9861667 DLAT trimer transfers acetyl to CoA IEA Xenopus tropicalis 29103 R-XTR-9861734 https://reactome.org/PathwayBrowser/#/R-XTR-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Xenopus tropicalis 29105 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 29105 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 29105 R-BTA-1237045 https://reactome.org/PathwayBrowser/#/R-BTA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Bos taurus 29105 R-BTA-1237047 https://reactome.org/PathwayBrowser/#/R-BTA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Bos taurus 29105 R-BTA-1237059 https://reactome.org/PathwayBrowser/#/R-BTA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Bos taurus 29105 R-BTA-1237081 https://reactome.org/PathwayBrowser/#/R-BTA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Bos taurus 29105 R-BTA-1474184 https://reactome.org/PathwayBrowser/#/R-BTA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Bos taurus 29105 R-BTA-1475017 https://reactome.org/PathwayBrowser/#/R-BTA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Bos taurus 29105 R-BTA-1475022 https://reactome.org/PathwayBrowser/#/R-BTA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Bos taurus 29105 R-BTA-1475025 https://reactome.org/PathwayBrowser/#/R-BTA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Bos taurus 29105 R-BTA-1475026 https://reactome.org/PathwayBrowser/#/R-BTA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Bos taurus 29105 R-BTA-1475028 https://reactome.org/PathwayBrowser/#/R-BTA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Bos taurus 29105 R-BTA-1475032 https://reactome.org/PathwayBrowser/#/R-BTA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Bos taurus 29105 R-BTA-1475422 https://reactome.org/PathwayBrowser/#/R-BTA-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Bos taurus 29105 R-BTA-1475435 https://reactome.org/PathwayBrowser/#/R-BTA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Bos taurus 29105 R-BTA-1475436 https://reactome.org/PathwayBrowser/#/R-BTA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Bos taurus 29105 R-BTA-1497784 https://reactome.org/PathwayBrowser/#/R-BTA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Bos taurus 29105 R-BTA-1497796 https://reactome.org/PathwayBrowser/#/R-BTA-1497796 BH2 binding can lead to eNOS uncoupling IEA Bos taurus 29105 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 29105 R-BTA-158354 https://reactome.org/PathwayBrowser/#/R-BTA-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer IEA Bos taurus 29105 R-BTA-158941 https://reactome.org/PathwayBrowser/#/R-BTA-158941 plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein IEA Bos taurus 29105 R-BTA-1614605 https://reactome.org/PathwayBrowser/#/R-BTA-1614605 Persulfide sulfur is dioxygenated IEA Bos taurus 29105 R-BTA-1614654 https://reactome.org/PathwayBrowser/#/R-BTA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Bos taurus 29105 R-BTA-174374 https://reactome.org/PathwayBrowser/#/R-BTA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Bos taurus 29105 R-BTA-189384 https://reactome.org/PathwayBrowser/#/R-BTA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Bos taurus 29105 R-BTA-189439 https://reactome.org/PathwayBrowser/#/R-BTA-189439 ALAD condenses 2 dALAs to form PBG IEA Bos taurus 29105 R-BTA-193679 https://reactome.org/PathwayBrowser/#/R-BTA-193679 alpha-secretase cleaves the p75NTR extracellular domain IEA Bos taurus 29105 R-BTA-197198 https://reactome.org/PathwayBrowser/#/R-BTA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Bos taurus 29105 R-BTA-200512 https://reactome.org/PathwayBrowser/#/R-BTA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 29105 R-BTA-202110 https://reactome.org/PathwayBrowser/#/R-BTA-202110 eNOS:Caveolin-1 complex binds to CaM IEA Bos taurus 29105 R-BTA-202111 https://reactome.org/PathwayBrowser/#/R-BTA-202111 AKT1 phosphorylates eNOS IEA Bos taurus 29105 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 29105 R-BTA-202129 https://reactome.org/PathwayBrowser/#/R-BTA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Bos taurus 29105 R-BTA-202132 https://reactome.org/PathwayBrowser/#/R-BTA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Bos taurus 29105 R-BTA-202144 https://reactome.org/PathwayBrowser/#/R-BTA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Bos taurus 29105 R-BTA-2022368 https://reactome.org/PathwayBrowser/#/R-BTA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Bos taurus 29105 R-BTA-2022378 https://reactome.org/PathwayBrowser/#/R-BTA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Bos taurus 29105 R-BTA-2022379 https://reactome.org/PathwayBrowser/#/R-BTA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Bos taurus 29105 R-BTA-2022396 https://reactome.org/PathwayBrowser/#/R-BTA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Bos taurus 29105 R-BTA-2022398 https://reactome.org/PathwayBrowser/#/R-BTA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Bos taurus 29105 R-BTA-2022399 https://reactome.org/PathwayBrowser/#/R-BTA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Bos taurus 29105 R-BTA-2022405 https://reactome.org/PathwayBrowser/#/R-BTA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 29105 R-BTA-2025890 https://reactome.org/PathwayBrowser/#/R-BTA-2025890 Calcineurin binds NFATC1,2,3 IEA Bos taurus 29105 R-BTA-2028294 https://reactome.org/PathwayBrowser/#/R-BTA-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Bos taurus 29105 R-BTA-203553 https://reactome.org/PathwayBrowser/#/R-BTA-203553 eNOS binds NOSIP IEA Bos taurus 29105 R-BTA-203565 https://reactome.org/PathwayBrowser/#/R-BTA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Bos taurus 29105 R-BTA-203613 https://reactome.org/PathwayBrowser/#/R-BTA-203613 depalmitoylation of eNOS IEA Bos taurus 29105 R-BTA-203625 https://reactome.org/PathwayBrowser/#/R-BTA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Bos taurus 29105 R-BTA-203680 https://reactome.org/PathwayBrowser/#/R-BTA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Bos taurus 29105 R-BTA-203700 https://reactome.org/PathwayBrowser/#/R-BTA-203700 eNOS translocation from Golgi to Caveolae IEA Bos taurus 29105 R-BTA-203712 https://reactome.org/PathwayBrowser/#/R-BTA-203712 eNOS associates with Caveolin-1 IEA Bos taurus 29105 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 29105 R-BTA-2161187 https://reactome.org/PathwayBrowser/#/R-BTA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Bos taurus 29105 R-BTA-2161195 https://reactome.org/PathwayBrowser/#/R-BTA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Bos taurus 29105 R-BTA-2162078 https://reactome.org/PathwayBrowser/#/R-BTA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Bos taurus 29105 R-BTA-264758 https://reactome.org/PathwayBrowser/#/R-BTA-264758 BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 IEA Bos taurus 29105 R-BTA-264976 https://reactome.org/PathwayBrowser/#/R-BTA-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Bos taurus 29105 R-BTA-265153 https://reactome.org/PathwayBrowser/#/R-BTA-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Bos taurus 29105 R-BTA-265682 https://reactome.org/PathwayBrowser/#/R-BTA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Bos taurus 29105 R-BTA-266012 https://reactome.org/PathwayBrowser/#/R-BTA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Bos taurus 29105 R-BTA-266072 https://reactome.org/PathwayBrowser/#/R-BTA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Bos taurus 29105 R-BTA-2730849 https://reactome.org/PathwayBrowser/#/R-BTA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Bos taurus 29105 R-BTA-2730867 https://reactome.org/PathwayBrowser/#/R-BTA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Bos taurus 29105 R-BTA-2730872 https://reactome.org/PathwayBrowser/#/R-BTA-2730872 Activation of Calcineurin IEA Bos taurus 29105 R-BTA-3149518 https://reactome.org/PathwayBrowser/#/R-BTA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Bos taurus 29105 R-BTA-3149539 https://reactome.org/PathwayBrowser/#/R-BTA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Bos taurus 29105 R-BTA-3204318 https://reactome.org/PathwayBrowser/#/R-BTA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Bos taurus 29105 R-BTA-3299682 https://reactome.org/PathwayBrowser/#/R-BTA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Bos taurus 29105 R-BTA-3299691 https://reactome.org/PathwayBrowser/#/R-BTA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Bos taurus 29105 R-BTA-3299753 https://reactome.org/PathwayBrowser/#/R-BTA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Bos taurus 29105 R-BTA-3371385 https://reactome.org/PathwayBrowser/#/R-BTA-3371385 TNF-α is cleaved by ADAM17 (TACE) IEA Bos taurus 29105 R-BTA-3697860 https://reactome.org/PathwayBrowser/#/R-BTA-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Bos taurus 29105 R-BTA-375176 https://reactome.org/PathwayBrowser/#/R-BTA-375176 Inactive catalytic PP2B is activated by the binding of calmodulin TAS Bos taurus 29105 R-BTA-3777112 https://reactome.org/PathwayBrowser/#/R-BTA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Bos taurus 29105 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 29105 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 29105 R-BTA-428262 https://reactome.org/PathwayBrowser/#/R-BTA-428262 ACER3 hydrolyzes phytoceramide IEA Bos taurus 29105 R-BTA-435171 https://reactome.org/PathwayBrowser/#/R-BTA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Bos taurus 29105 R-BTA-435366 https://reactome.org/PathwayBrowser/#/R-BTA-435366 ZnT1 mediates the efflux of zinc from the cell IEA Bos taurus 29105 R-BTA-437085 https://reactome.org/PathwayBrowser/#/R-BTA-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Bos taurus 29105 R-BTA-437136 https://reactome.org/PathwayBrowser/#/R-BTA-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Bos taurus 29105 R-BTA-437139 https://reactome.org/PathwayBrowser/#/R-BTA-437139 ZnT8 transports zinc into the Golgi apparatus IEA Bos taurus 29105 R-BTA-442317 https://reactome.org/PathwayBrowser/#/R-BTA-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Bos taurus 29105 R-BTA-442387 https://reactome.org/PathwayBrowser/#/R-BTA-442387 ZIP8 mediates zinc influx into cells IEA Bos taurus 29105 R-BTA-442393 https://reactome.org/PathwayBrowser/#/R-BTA-442393 ZIP7 mediates zinc efflux from the endoplasmic reticulum IEA Bos taurus 29105 R-BTA-442422 https://reactome.org/PathwayBrowser/#/R-BTA-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Bos taurus 29105 R-BTA-444572 https://reactome.org/PathwayBrowser/#/R-BTA-444572 Zinc is an agonist of GPR39 IEA Bos taurus 29105 R-BTA-4551451 https://reactome.org/PathwayBrowser/#/R-BTA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Bos taurus 29105 R-BTA-4551465 https://reactome.org/PathwayBrowser/#/R-BTA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Bos taurus 29105 R-BTA-4837364 https://reactome.org/PathwayBrowser/#/R-BTA-4837364 Secretion of SOD3 IEA Bos taurus 29105 R-BTA-5362564 https://reactome.org/PathwayBrowser/#/R-BTA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Bos taurus 29105 R-BTA-5433067 https://reactome.org/PathwayBrowser/#/R-BTA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Bos taurus 29105 R-BTA-5433074 https://reactome.org/PathwayBrowser/#/R-BTA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Bos taurus 29105 R-BTA-5652195 https://reactome.org/PathwayBrowser/#/R-BTA-5652195 SORD oxidizes D-sorbitol to Fru IEA Bos taurus 29105 R-BTA-5661217 https://reactome.org/PathwayBrowser/#/R-BTA-5661217 MT1A binds zinc IEA Bos taurus 29105 R-BTA-5662471 https://reactome.org/PathwayBrowser/#/R-BTA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Bos taurus 29105 R-BTA-5662606 https://reactome.org/PathwayBrowser/#/R-BTA-5662606 MT3 binds zinc IEA Bos taurus 29105 R-BTA-5662613 https://reactome.org/PathwayBrowser/#/R-BTA-5662613 MT3 exchanges zinc for copper IEA Bos taurus 29105 R-BTA-5662660 https://reactome.org/PathwayBrowser/#/R-BTA-5662660 Dopachrome is transformed to DHICA by DCT IEA Bos taurus 29105 R-BTA-5682586 https://reactome.org/PathwayBrowser/#/R-BTA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Bos taurus 29105 R-BTA-5682588 https://reactome.org/PathwayBrowser/#/R-BTA-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Bos taurus 29105 R-BTA-5682598 https://reactome.org/PathwayBrowser/#/R-BTA-5682598 ATM phosphorylates HERC2 IEA Bos taurus 29105 R-BTA-5682607 https://reactome.org/PathwayBrowser/#/R-BTA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Bos taurus 29105 R-BTA-5682629 https://reactome.org/PathwayBrowser/#/R-BTA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Bos taurus 29105 R-BTA-5682858 https://reactome.org/PathwayBrowser/#/R-BTA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Bos taurus 29105 R-BTA-5682863 https://reactome.org/PathwayBrowser/#/R-BTA-5682863 RNF168 binds DNA DSBs IEA Bos taurus 29105 R-BTA-5683077 https://reactome.org/PathwayBrowser/#/R-BTA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Bos taurus 29105 R-BTA-5683384 https://reactome.org/PathwayBrowser/#/R-BTA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Bos taurus 29105 R-BTA-5683385 https://reactome.org/PathwayBrowser/#/R-BTA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Bos taurus 29105 R-BTA-5683405 https://reactome.org/PathwayBrowser/#/R-BTA-5683405 PPP5C dephosphorylates TP53BP1 IEA Bos taurus 29105 R-BTA-5683425 https://reactome.org/PathwayBrowser/#/R-BTA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Bos taurus 29105 R-BTA-5683735 https://reactome.org/PathwayBrowser/#/R-BTA-5683735 CHEK2 is recruited to DNA DSBs IEA Bos taurus 29105 R-BTA-5683801 https://reactome.org/PathwayBrowser/#/R-BTA-5683801 CHEK2 phosphorylates BRCA1 IEA Bos taurus 29105 R-BTA-5684052 https://reactome.org/PathwayBrowser/#/R-BTA-5684052 PIAS4 SUMOylates MDC1 IEA Bos taurus 29105 R-BTA-5684071 https://reactome.org/PathwayBrowser/#/R-BTA-5684071 RNF4 ubiquitinates MDC1 IEA Bos taurus 29105 R-BTA-5686685 https://reactome.org/PathwayBrowser/#/R-BTA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Bos taurus 29105 R-BTA-5686704 https://reactome.org/PathwayBrowser/#/R-BTA-5686704 Activated ATM phosphorylates DCLRE1C IEA Bos taurus 29105 R-BTA-5686900 https://reactome.org/PathwayBrowser/#/R-BTA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Bos taurus 29105 R-BTA-5688276 https://reactome.org/PathwayBrowser/#/R-BTA-5688276 SIRT4 transfers ADPRib to GLUD IEA Bos taurus 29105 R-BTA-5688289 https://reactome.org/PathwayBrowser/#/R-BTA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Bos taurus 29105 R-BTA-5688294 https://reactome.org/PathwayBrowser/#/R-BTA-5688294 SIRT5 deacetylates Cytochrome C IEA Bos taurus 29105 R-BTA-5691507 https://reactome.org/PathwayBrowser/#/R-BTA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Bos taurus 29105 R-BTA-5692237 https://reactome.org/PathwayBrowser/#/R-BTA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Bos taurus 29105 R-BTA-5693346 https://reactome.org/PathwayBrowser/#/R-BTA-5693346 CECRI deaminates Ade-Rib to Ino IEA Bos taurus 29105 R-BTA-5693551 https://reactome.org/PathwayBrowser/#/R-BTA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Bos taurus 29105 R-BTA-5693566 https://reactome.org/PathwayBrowser/#/R-BTA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Bos taurus 29105 R-BTA-5693599 https://reactome.org/PathwayBrowser/#/R-BTA-5693599 Association of Ku heterodimer with ends of DNA double-strand break IEA Bos taurus 29105 R-BTA-5694071 https://reactome.org/PathwayBrowser/#/R-BTA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Bos taurus 29105 R-BTA-5696838 https://reactome.org/PathwayBrowser/#/R-BTA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Bos taurus 29105 R-BTA-6783221 https://reactome.org/PathwayBrowser/#/R-BTA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Bos taurus 29105 R-BTA-6788650 https://reactome.org/PathwayBrowser/#/R-BTA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Bos taurus 29105 R-BTA-6789072 https://reactome.org/PathwayBrowser/#/R-BTA-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Bos taurus 29105 R-BTA-6798474 https://reactome.org/PathwayBrowser/#/R-BTA-6798474 S100A8:S100A9 binds Zn2+ IEA Bos taurus 29105 R-BTA-6798489 https://reactome.org/PathwayBrowser/#/R-BTA-6798489 S100A7 or S100A7A binds Zn2+ IEA Bos taurus 29105 R-BTA-6799545 https://reactome.org/PathwayBrowser/#/R-BTA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Bos taurus 29105 R-BTA-6799581 https://reactome.org/PathwayBrowser/#/R-BTA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Bos taurus 29105 R-BTA-6799959 https://reactome.org/PathwayBrowser/#/R-BTA-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Bos taurus 29105 R-BTA-6799977 https://reactome.org/PathwayBrowser/#/R-BTA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Bos taurus 29105 R-BTA-69891 https://reactome.org/PathwayBrowser/#/R-BTA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Bos taurus 29105 R-BTA-71707 https://reactome.org/PathwayBrowser/#/R-BTA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Bos taurus 29105 R-BTA-73589 https://reactome.org/PathwayBrowser/#/R-BTA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Bos taurus 29105 R-BTA-73591 https://reactome.org/PathwayBrowser/#/R-BTA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Bos taurus 29105 R-BTA-73608 https://reactome.org/PathwayBrowser/#/R-BTA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Bos taurus 29105 R-BTA-73618 https://reactome.org/PathwayBrowser/#/R-BTA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Bos taurus 29105 R-BTA-73620 https://reactome.org/PathwayBrowser/#/R-BTA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Bos taurus 29105 R-BTA-74255 https://reactome.org/PathwayBrowser/#/R-BTA-74255 Guanine + H2O => Xanthine + NH4+ IEA Bos taurus 29105 R-BTA-74730 https://reactome.org/PathwayBrowser/#/R-BTA-74730 Insulin degradation IEA Bos taurus 29105 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 29105 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 29105 R-BTA-880007 https://reactome.org/PathwayBrowser/#/R-BTA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Bos taurus 29105 R-BTA-8853686 https://reactome.org/PathwayBrowser/#/R-BTA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Bos taurus 29105 R-BTA-8866601 https://reactome.org/PathwayBrowser/#/R-BTA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Bos taurus 29105 R-BTA-8867344 https://reactome.org/PathwayBrowser/#/R-BTA-8867344 OMA1 hydrolyses OPA1 IEA Bos taurus 29105 R-BTA-8878787 https://reactome.org/PathwayBrowser/#/R-BTA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Bos taurus 29105 R-BTA-8940070 https://reactome.org/PathwayBrowser/#/R-BTA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Bos taurus 29105 R-BTA-8940074 https://reactome.org/PathwayBrowser/#/R-BTA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Bos taurus 29105 R-BTA-8949649 https://reactome.org/PathwayBrowser/#/R-BTA-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) IEA Bos taurus 29105 R-BTA-8949659 https://reactome.org/PathwayBrowser/#/R-BTA-8949659 AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU IEA Bos taurus 29105 R-BTA-8949661 https://reactome.org/PathwayBrowser/#/R-BTA-8949661 C2orf47:AFG3L2 binds the transit peptide of SMDT1 IEA Bos taurus 29105 R-BTA-8949668 https://reactome.org/PathwayBrowser/#/R-BTA-8949668 YME1L1 proteolyzes unassembled proSMDT1 IEA Bos taurus 29105 R-BTA-8951723 https://reactome.org/PathwayBrowser/#/R-BTA-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Bos taurus 29105 R-BTA-9018862 https://reactome.org/PathwayBrowser/#/R-BTA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Bos taurus 29105 R-BTA-9018877 https://reactome.org/PathwayBrowser/#/R-BTA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Bos taurus 29105 R-BTA-9020252 https://reactome.org/PathwayBrowser/#/R-BTA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Bos taurus 29105 R-BTA-9020253 https://reactome.org/PathwayBrowser/#/R-BTA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Bos taurus 29105 R-BTA-9020257 https://reactome.org/PathwayBrowser/#/R-BTA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Bos taurus 29105 R-BTA-9020258 https://reactome.org/PathwayBrowser/#/R-BTA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Bos taurus 29105 R-BTA-9020270 https://reactome.org/PathwayBrowser/#/R-BTA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Bos taurus 29105 R-BTA-9024890 https://reactome.org/PathwayBrowser/#/R-BTA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Bos taurus 29105 R-BTA-947514 https://reactome.org/PathwayBrowser/#/R-BTA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Bos taurus 29105 R-BTA-9610152 https://reactome.org/PathwayBrowser/#/R-BTA-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Bos taurus 29105 R-BTA-9610153 https://reactome.org/PathwayBrowser/#/R-BTA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Bos taurus 29105 R-BTA-9610154 https://reactome.org/PathwayBrowser/#/R-BTA-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Bos taurus 29105 R-BTA-9610156 https://reactome.org/PathwayBrowser/#/R-BTA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Bos taurus 29105 R-BTA-9610163 https://reactome.org/PathwayBrowser/#/R-BTA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Bos taurus 29105 R-BTA-9647977 https://reactome.org/PathwayBrowser/#/R-BTA-9647977 ICMT methylates S-Farn RAS proteins IEA Bos taurus 29105 R-BTA-964958 https://reactome.org/PathwayBrowser/#/R-BTA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Bos taurus 29105 R-BTA-964962 https://reactome.org/PathwayBrowser/#/R-BTA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Bos taurus 29105 R-BTA-964970 https://reactome.org/PathwayBrowser/#/R-BTA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Bos taurus 29105 R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 29105 R-BTA-9727607 https://reactome.org/PathwayBrowser/#/R-BTA-9727607 MME:Zn2+ binds sacubitrilat IEA Bos taurus 29105 R-BTA-9731661 https://reactome.org/PathwayBrowser/#/R-BTA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Bos taurus 29105 R-BTA-9753944 https://reactome.org/PathwayBrowser/#/R-BTA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Bos taurus 29105 R-BTA-975814 https://reactome.org/PathwayBrowser/#/R-BTA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Bos taurus 29105 R-BTA-9820566 https://reactome.org/PathwayBrowser/#/R-BTA-9820566 ZnT5 transports zinc into the golgi apparatus IEA Bos taurus 29105 R-BTA-9838627 https://reactome.org/PathwayBrowser/#/R-BTA-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Bos taurus 29105 R-BTA-9839053 https://reactome.org/PathwayBrowser/#/R-BTA-9839053 AFG3L2:SPG7 binds SMDT1 (EMRE) IEA Bos taurus 29105 R-BTA-9839059 https://reactome.org/PathwayBrowser/#/R-BTA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Bos taurus 29105 R-BTA-9839105 https://reactome.org/PathwayBrowser/#/R-BTA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Bos taurus 29105 R-BTA-9839113 https://reactome.org/PathwayBrowser/#/R-BTA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Bos taurus 29105 R-BTA-9839149 https://reactome.org/PathwayBrowser/#/R-BTA-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Bos taurus 29105 R-BTA-9840408 https://reactome.org/PathwayBrowser/#/R-BTA-9840408 OMA1 cleaves DELE1 IEA Bos taurus 29105 R-BTA-9840564 https://reactome.org/PathwayBrowser/#/R-BTA-9840564 OMA1 hydrolyzes YME1L1 IEA Bos taurus 29105 R-BTA-9854463 https://reactome.org/PathwayBrowser/#/R-BTA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Bos taurus 29105 R-BTA-9861626 https://reactome.org/PathwayBrowser/#/R-BTA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Bos taurus 29105 R-CEL-1237045 https://reactome.org/PathwayBrowser/#/R-CEL-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Caenorhabditis elegans 29105 R-CEL-1237047 https://reactome.org/PathwayBrowser/#/R-CEL-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Caenorhabditis elegans 29105 R-CEL-1237059 https://reactome.org/PathwayBrowser/#/R-CEL-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Caenorhabditis elegans 29105 R-CEL-1237081 https://reactome.org/PathwayBrowser/#/R-CEL-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Caenorhabditis elegans 29105 R-CEL-1474184 https://reactome.org/PathwayBrowser/#/R-CEL-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Caenorhabditis elegans 29105 R-CEL-1475017 https://reactome.org/PathwayBrowser/#/R-CEL-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Caenorhabditis elegans 29105 R-CEL-1475022 https://reactome.org/PathwayBrowser/#/R-CEL-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Caenorhabditis elegans 29105 R-CEL-1475025 https://reactome.org/PathwayBrowser/#/R-CEL-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Caenorhabditis elegans 29105 R-CEL-1475026 https://reactome.org/PathwayBrowser/#/R-CEL-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Caenorhabditis elegans 29105 R-CEL-1475028 https://reactome.org/PathwayBrowser/#/R-CEL-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Caenorhabditis elegans 29105 R-CEL-1475032 https://reactome.org/PathwayBrowser/#/R-CEL-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Caenorhabditis elegans 29105 R-CEL-1475435 https://reactome.org/PathwayBrowser/#/R-CEL-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Caenorhabditis elegans 29105 R-CEL-1475436 https://reactome.org/PathwayBrowser/#/R-CEL-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Caenorhabditis elegans 29105 R-CEL-1497784 https://reactome.org/PathwayBrowser/#/R-CEL-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Caenorhabditis elegans 29105 R-CEL-1497796 https://reactome.org/PathwayBrowser/#/R-CEL-1497796 BH2 binding can lead to eNOS uncoupling IEA Caenorhabditis elegans 29105 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 29105 R-CEL-1614605 https://reactome.org/PathwayBrowser/#/R-CEL-1614605 Persulfide sulfur is dioxygenated IEA Caenorhabditis elegans 29105 R-CEL-174374 https://reactome.org/PathwayBrowser/#/R-CEL-174374 MTR transfers CH3 from MeCbl to HCYS IEA Caenorhabditis elegans 29105 R-CEL-200512 https://reactome.org/PathwayBrowser/#/R-CEL-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 29105 R-CEL-202111 https://reactome.org/PathwayBrowser/#/R-CEL-202111 AKT1 phosphorylates eNOS IEA Caenorhabditis elegans 29105 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 29105 R-CEL-2022368 https://reactome.org/PathwayBrowser/#/R-CEL-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Caenorhabditis elegans 29105 R-CEL-2022396 https://reactome.org/PathwayBrowser/#/R-CEL-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Caenorhabditis elegans 29105 R-CEL-2022398 https://reactome.org/PathwayBrowser/#/R-CEL-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Caenorhabditis elegans 29105 R-CEL-2022399 https://reactome.org/PathwayBrowser/#/R-CEL-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Caenorhabditis elegans 29105 R-CEL-2022405 https://reactome.org/PathwayBrowser/#/R-CEL-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 29105 R-CEL-2028294 https://reactome.org/PathwayBrowser/#/R-CEL-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Caenorhabditis elegans 29105 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 29105 R-CEL-2161187 https://reactome.org/PathwayBrowser/#/R-CEL-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Caenorhabditis elegans 29105 R-CEL-2161195 https://reactome.org/PathwayBrowser/#/R-CEL-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Caenorhabditis elegans 29105 R-CEL-2162078 https://reactome.org/PathwayBrowser/#/R-CEL-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Caenorhabditis elegans 29105 R-CEL-266072 https://reactome.org/PathwayBrowser/#/R-CEL-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Caenorhabditis elegans 29105 R-CEL-2730867 https://reactome.org/PathwayBrowser/#/R-CEL-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Caenorhabditis elegans 29105 R-CEL-2730872 https://reactome.org/PathwayBrowser/#/R-CEL-2730872 Activation of Calcineurin IEA Caenorhabditis elegans 29105 R-CEL-3149518 https://reactome.org/PathwayBrowser/#/R-CEL-3149518 MTRR reduces cob(II)alamin to meCbl IEA Caenorhabditis elegans 29105 R-CEL-3149539 https://reactome.org/PathwayBrowser/#/R-CEL-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Caenorhabditis elegans 29105 R-CEL-3204318 https://reactome.org/PathwayBrowser/#/R-CEL-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Caenorhabditis elegans 29105 R-CEL-3299691 https://reactome.org/PathwayBrowser/#/R-CEL-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Caenorhabditis elegans 29105 R-CEL-3777112 https://reactome.org/PathwayBrowser/#/R-CEL-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Caenorhabditis elegans 29105 R-CEL-435171 https://reactome.org/PathwayBrowser/#/R-CEL-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Caenorhabditis elegans 29105 R-CEL-435366 https://reactome.org/PathwayBrowser/#/R-CEL-435366 ZnT1 mediates the efflux of zinc from the cell IEA Caenorhabditis elegans 29105 R-CEL-437085 https://reactome.org/PathwayBrowser/#/R-CEL-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Caenorhabditis elegans 29105 R-CEL-437136 https://reactome.org/PathwayBrowser/#/R-CEL-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Caenorhabditis elegans 29105 R-CEL-437139 https://reactome.org/PathwayBrowser/#/R-CEL-437139 ZnT8 transports zinc into the Golgi apparatus IEA Caenorhabditis elegans 29105 R-CEL-442317 https://reactome.org/PathwayBrowser/#/R-CEL-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Caenorhabditis elegans 29105 R-CEL-442387 https://reactome.org/PathwayBrowser/#/R-CEL-442387 ZIP8 mediates zinc influx into cells IEA Caenorhabditis elegans 29105 R-CEL-442393 https://reactome.org/PathwayBrowser/#/R-CEL-442393 ZIP7 mediates zinc efflux from the endoplasmic reticulum IEA Caenorhabditis elegans 29105 R-CEL-442422 https://reactome.org/PathwayBrowser/#/R-CEL-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Caenorhabditis elegans 29105 R-CEL-4551465 https://reactome.org/PathwayBrowser/#/R-CEL-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Caenorhabditis elegans 29105 R-CEL-5362564 https://reactome.org/PathwayBrowser/#/R-CEL-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Caenorhabditis elegans 29105 R-CEL-5433074 https://reactome.org/PathwayBrowser/#/R-CEL-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Caenorhabditis elegans 29105 R-CEL-5652195 https://reactome.org/PathwayBrowser/#/R-CEL-5652195 SORD oxidizes D-sorbitol to Fru IEA Caenorhabditis elegans 29105 R-CEL-5662471 https://reactome.org/PathwayBrowser/#/R-CEL-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Caenorhabditis elegans 29105 R-CEL-5662660 https://reactome.org/PathwayBrowser/#/R-CEL-5662660 Dopachrome is transformed to DHICA by DCT IEA Caenorhabditis elegans 29105 R-CEL-5688276 https://reactome.org/PathwayBrowser/#/R-CEL-5688276 SIRT4 transfers ADPRib to GLUD IEA Caenorhabditis elegans 29105 R-CEL-5692237 https://reactome.org/PathwayBrowser/#/R-CEL-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Caenorhabditis elegans 29105 R-CEL-6783221 https://reactome.org/PathwayBrowser/#/R-CEL-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Caenorhabditis elegans 29105 R-CEL-6788650 https://reactome.org/PathwayBrowser/#/R-CEL-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Caenorhabditis elegans 29105 R-CEL-6799581 https://reactome.org/PathwayBrowser/#/R-CEL-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Caenorhabditis elegans 29105 R-CEL-71707 https://reactome.org/PathwayBrowser/#/R-CEL-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Caenorhabditis elegans 29105 R-CEL-73589 https://reactome.org/PathwayBrowser/#/R-CEL-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Caenorhabditis elegans 29105 R-CEL-73591 https://reactome.org/PathwayBrowser/#/R-CEL-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Caenorhabditis elegans 29105 R-CEL-73608 https://reactome.org/PathwayBrowser/#/R-CEL-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Caenorhabditis elegans 29105 R-CEL-73618 https://reactome.org/PathwayBrowser/#/R-CEL-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Caenorhabditis elegans 29105 R-CEL-73620 https://reactome.org/PathwayBrowser/#/R-CEL-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Caenorhabditis elegans 29105 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 29105 R-CEL-880007 https://reactome.org/PathwayBrowser/#/R-CEL-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Caenorhabditis elegans 29105 R-CEL-8853686 https://reactome.org/PathwayBrowser/#/R-CEL-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Caenorhabditis elegans 29105 R-CEL-8866601 https://reactome.org/PathwayBrowser/#/R-CEL-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Caenorhabditis elegans 29105 R-CEL-8949649 https://reactome.org/PathwayBrowser/#/R-CEL-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) IEA Caenorhabditis elegans 29105 R-CEL-8949659 https://reactome.org/PathwayBrowser/#/R-CEL-8949659 AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU IEA Caenorhabditis elegans 29105 R-CEL-8949661 https://reactome.org/PathwayBrowser/#/R-CEL-8949661 C2orf47:AFG3L2 binds the transit peptide of SMDT1 IEA Caenorhabditis elegans 29105 R-CEL-9018862 https://reactome.org/PathwayBrowser/#/R-CEL-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Caenorhabditis elegans 29105 R-CEL-9018877 https://reactome.org/PathwayBrowser/#/R-CEL-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Caenorhabditis elegans 29105 R-CEL-9020252 https://reactome.org/PathwayBrowser/#/R-CEL-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Caenorhabditis elegans 29105 R-CEL-9020253 https://reactome.org/PathwayBrowser/#/R-CEL-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Caenorhabditis elegans 29105 R-CEL-9020257 https://reactome.org/PathwayBrowser/#/R-CEL-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Caenorhabditis elegans 29105 R-CEL-9020258 https://reactome.org/PathwayBrowser/#/R-CEL-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Caenorhabditis elegans 29105 R-CEL-9020270 https://reactome.org/PathwayBrowser/#/R-CEL-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Caenorhabditis elegans 29105 R-CEL-9024890 https://reactome.org/PathwayBrowser/#/R-CEL-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Caenorhabditis elegans 29105 R-CEL-947514 https://reactome.org/PathwayBrowser/#/R-CEL-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Caenorhabditis elegans 29105 R-CEL-9610152 https://reactome.org/PathwayBrowser/#/R-CEL-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Caenorhabditis elegans 29105 R-CEL-9610153 https://reactome.org/PathwayBrowser/#/R-CEL-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Caenorhabditis elegans 29105 R-CEL-9610154 https://reactome.org/PathwayBrowser/#/R-CEL-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Caenorhabditis elegans 29105 R-CEL-9610156 https://reactome.org/PathwayBrowser/#/R-CEL-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Caenorhabditis elegans 29105 R-CEL-9610163 https://reactome.org/PathwayBrowser/#/R-CEL-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Caenorhabditis elegans 29105 R-CEL-9647977 https://reactome.org/PathwayBrowser/#/R-CEL-9647977 ICMT methylates S-Farn RAS proteins IEA Caenorhabditis elegans 29105 R-CEL-964958 https://reactome.org/PathwayBrowser/#/R-CEL-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Caenorhabditis elegans 29105 R-CEL-964962 https://reactome.org/PathwayBrowser/#/R-CEL-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Caenorhabditis elegans 29105 R-CEL-964970 https://reactome.org/PathwayBrowser/#/R-CEL-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Caenorhabditis elegans 29105 R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 29105 R-CEL-9727607 https://reactome.org/PathwayBrowser/#/R-CEL-9727607 MME:Zn2+ binds sacubitrilat IEA Caenorhabditis elegans 29105 R-CEL-9731661 https://reactome.org/PathwayBrowser/#/R-CEL-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Caenorhabditis elegans 29105 R-CEL-9753944 https://reactome.org/PathwayBrowser/#/R-CEL-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Caenorhabditis elegans 29105 R-CEL-975814 https://reactome.org/PathwayBrowser/#/R-CEL-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Caenorhabditis elegans 29105 R-CEL-9820566 https://reactome.org/PathwayBrowser/#/R-CEL-9820566 ZnT5 transports zinc into the golgi apparatus IEA Caenorhabditis elegans 29105 R-CEL-9838627 https://reactome.org/PathwayBrowser/#/R-CEL-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Caenorhabditis elegans 29105 R-CEL-9839053 https://reactome.org/PathwayBrowser/#/R-CEL-9839053 AFG3L2:SPG7 binds SMDT1 (EMRE) IEA Caenorhabditis elegans 29105 R-CEL-9839059 https://reactome.org/PathwayBrowser/#/R-CEL-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Caenorhabditis elegans 29105 R-CEL-9839105 https://reactome.org/PathwayBrowser/#/R-CEL-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 29105 R-CEL-9839113 https://reactome.org/PathwayBrowser/#/R-CEL-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Caenorhabditis elegans 29105 R-CEL-9839149 https://reactome.org/PathwayBrowser/#/R-CEL-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Caenorhabditis elegans 29105 R-CEL-9861626 https://reactome.org/PathwayBrowser/#/R-CEL-9861626 SIRT4 cleaves lipoyl from DLAT IEA Caenorhabditis elegans 29105 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 29105 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 29105 R-CFA-1170539 https://reactome.org/PathwayBrowser/#/R-CFA-1170539 Prolactin receptor is internalized IEA Canis familiaris 29105 R-CFA-1237045 https://reactome.org/PathwayBrowser/#/R-CFA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Canis familiaris 29105 R-CFA-1237047 https://reactome.org/PathwayBrowser/#/R-CFA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Canis familiaris 29105 R-CFA-1237059 https://reactome.org/PathwayBrowser/#/R-CFA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Canis familiaris 29105 R-CFA-1237081 https://reactome.org/PathwayBrowser/#/R-CFA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Canis familiaris 29105 R-CFA-1370500 https://reactome.org/PathwayBrowser/#/R-CFA-1370500 PRLR binds SCF beta-TrCP complex IEA Canis familiaris 29105 R-CFA-1370505 https://reactome.org/PathwayBrowser/#/R-CFA-1370505 PRLR is phosphorylated at Ser-349 IEA Canis familiaris 29105 R-CFA-1475017 https://reactome.org/PathwayBrowser/#/R-CFA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Canis familiaris 29105 R-CFA-1475022 https://reactome.org/PathwayBrowser/#/R-CFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Canis familiaris 29105 R-CFA-1475025 https://reactome.org/PathwayBrowser/#/R-CFA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Canis familiaris 29105 R-CFA-1475026 https://reactome.org/PathwayBrowser/#/R-CFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Canis familiaris 29105 R-CFA-1475028 https://reactome.org/PathwayBrowser/#/R-CFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Canis familiaris 29105 R-CFA-1475032 https://reactome.org/PathwayBrowser/#/R-CFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Canis familiaris 29105 R-CFA-1475435 https://reactome.org/PathwayBrowser/#/R-CFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Canis familiaris 29105 R-CFA-1475436 https://reactome.org/PathwayBrowser/#/R-CFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Canis familiaris 29105 R-CFA-158354 https://reactome.org/PathwayBrowser/#/R-CFA-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer IEA Canis familiaris 29105 R-CFA-158941 https://reactome.org/PathwayBrowser/#/R-CFA-158941 plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein IEA Canis familiaris 29105 R-CFA-1614605 https://reactome.org/PathwayBrowser/#/R-CFA-1614605 Persulfide sulfur is dioxygenated IEA Canis familiaris 29105 R-CFA-1614654 https://reactome.org/PathwayBrowser/#/R-CFA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Canis familiaris 29105 R-CFA-1671687 https://reactome.org/PathwayBrowser/#/R-CFA-1671687 PRLR activation IEA Canis familiaris 29105 R-CFA-1675473 https://reactome.org/PathwayBrowser/#/R-CFA-1675473 SH2B binds JAK2 IEA Canis familiaris 29105 R-CFA-174374 https://reactome.org/PathwayBrowser/#/R-CFA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Canis familiaris 29105 R-CFA-189384 https://reactome.org/PathwayBrowser/#/R-CFA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Canis familiaris 29105 R-CFA-189439 https://reactome.org/PathwayBrowser/#/R-CFA-189439 ALAD condenses 2 dALAs to form PBG IEA Canis familiaris 29105 R-CFA-193679 https://reactome.org/PathwayBrowser/#/R-CFA-193679 alpha-secretase cleaves the p75NTR extracellular domain IEA Canis familiaris 29105 R-CFA-197198 https://reactome.org/PathwayBrowser/#/R-CFA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Canis familiaris 29105 R-CFA-200512 https://reactome.org/PathwayBrowser/#/R-CFA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 29105 R-CFA-2022368 https://reactome.org/PathwayBrowser/#/R-CFA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Canis familiaris 29105 R-CFA-2022378 https://reactome.org/PathwayBrowser/#/R-CFA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Canis familiaris 29105 R-CFA-2022379 https://reactome.org/PathwayBrowser/#/R-CFA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Canis familiaris 29105 R-CFA-2022396 https://reactome.org/PathwayBrowser/#/R-CFA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Canis familiaris 29105 R-CFA-2022398 https://reactome.org/PathwayBrowser/#/R-CFA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Canis familiaris 29105 R-CFA-2022399 https://reactome.org/PathwayBrowser/#/R-CFA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Canis familiaris 29105 R-CFA-2022405 https://reactome.org/PathwayBrowser/#/R-CFA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 29105 R-CFA-2025890 https://reactome.org/PathwayBrowser/#/R-CFA-2025890 Calcineurin binds NFATC1,2,3 IEA Canis familiaris 29105 R-CFA-2028294 https://reactome.org/PathwayBrowser/#/R-CFA-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Canis familiaris 29105 R-CFA-203565 https://reactome.org/PathwayBrowser/#/R-CFA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Canis familiaris 29105 R-CFA-203625 https://reactome.org/PathwayBrowser/#/R-CFA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Canis familiaris 29105 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 29105 R-CFA-2161187 https://reactome.org/PathwayBrowser/#/R-CFA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Canis familiaris 29105 R-CFA-2161195 https://reactome.org/PathwayBrowser/#/R-CFA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Canis familiaris 29105 R-CFA-2162078 https://reactome.org/PathwayBrowser/#/R-CFA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Canis familiaris 29105 R-CFA-264758 https://reactome.org/PathwayBrowser/#/R-CFA-264758 BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 IEA Canis familiaris 29105 R-CFA-264976 https://reactome.org/PathwayBrowser/#/R-CFA-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Canis familiaris 29105 R-CFA-265153 https://reactome.org/PathwayBrowser/#/R-CFA-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Canis familiaris 29105 R-CFA-265682 https://reactome.org/PathwayBrowser/#/R-CFA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Canis familiaris 29105 R-CFA-266012 https://reactome.org/PathwayBrowser/#/R-CFA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Canis familiaris 29105 R-CFA-266072 https://reactome.org/PathwayBrowser/#/R-CFA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Canis familiaris 29105 R-CFA-2730849 https://reactome.org/PathwayBrowser/#/R-CFA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Canis familiaris 29105 R-CFA-2730867 https://reactome.org/PathwayBrowser/#/R-CFA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Canis familiaris 29105 R-CFA-2730872 https://reactome.org/PathwayBrowser/#/R-CFA-2730872 Activation of Calcineurin IEA Canis familiaris 29105 R-CFA-3149518 https://reactome.org/PathwayBrowser/#/R-CFA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Canis familiaris 29105 R-CFA-3149539 https://reactome.org/PathwayBrowser/#/R-CFA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Canis familiaris 29105 R-CFA-3204318 https://reactome.org/PathwayBrowser/#/R-CFA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Canis familiaris 29105 R-CFA-3299682 https://reactome.org/PathwayBrowser/#/R-CFA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Canis familiaris 29105 R-CFA-3299691 https://reactome.org/PathwayBrowser/#/R-CFA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Canis familiaris 29105 R-CFA-3299753 https://reactome.org/PathwayBrowser/#/R-CFA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Canis familiaris 29105 R-CFA-3371385 https://reactome.org/PathwayBrowser/#/R-CFA-3371385 TNF-α is cleaved by ADAM17 (TACE) IEA Canis familiaris 29105 R-CFA-3697860 https://reactome.org/PathwayBrowser/#/R-CFA-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Canis familiaris 29105 R-CFA-3777112 https://reactome.org/PathwayBrowser/#/R-CFA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Canis familiaris 29105 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 29105 R-CFA-428262 https://reactome.org/PathwayBrowser/#/R-CFA-428262 ACER3 hydrolyzes phytoceramide IEA Canis familiaris 29105 R-CFA-435171 https://reactome.org/PathwayBrowser/#/R-CFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Canis familiaris 29105 R-CFA-435366 https://reactome.org/PathwayBrowser/#/R-CFA-435366 ZnT1 mediates the efflux of zinc from the cell IEA Canis familiaris 29105 R-CFA-437085 https://reactome.org/PathwayBrowser/#/R-CFA-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Canis familiaris 29105 R-CFA-437136 https://reactome.org/PathwayBrowser/#/R-CFA-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Canis familiaris 29105 R-CFA-437139 https://reactome.org/PathwayBrowser/#/R-CFA-437139 ZnT8 transports zinc into the Golgi apparatus IEA Canis familiaris 29105 R-CFA-442317 https://reactome.org/PathwayBrowser/#/R-CFA-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Canis familiaris 29105 R-CFA-442387 https://reactome.org/PathwayBrowser/#/R-CFA-442387 ZIP8 mediates zinc influx into cells IEA Canis familiaris 29105 R-CFA-442393 https://reactome.org/PathwayBrowser/#/R-CFA-442393 ZIP7 mediates zinc efflux from the endoplasmic reticulum IEA Canis familiaris 29105 R-CFA-442422 https://reactome.org/PathwayBrowser/#/R-CFA-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Canis familiaris 29105 R-CFA-444572 https://reactome.org/PathwayBrowser/#/R-CFA-444572 Zinc is an agonist of GPR39 IEA Canis familiaris 29105 R-CFA-4551451 https://reactome.org/PathwayBrowser/#/R-CFA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Canis familiaris 29105 R-CFA-4551465 https://reactome.org/PathwayBrowser/#/R-CFA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Canis familiaris 29105 R-CFA-4837364 https://reactome.org/PathwayBrowser/#/R-CFA-4837364 Secretion of SOD3 IEA Canis familiaris 29105 R-CFA-5362564 https://reactome.org/PathwayBrowser/#/R-CFA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Canis familiaris 29105 R-CFA-5433067 https://reactome.org/PathwayBrowser/#/R-CFA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Canis familiaris 29105 R-CFA-5433074 https://reactome.org/PathwayBrowser/#/R-CFA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Canis familiaris 29105 R-CFA-5652195 https://reactome.org/PathwayBrowser/#/R-CFA-5652195 SORD oxidizes D-sorbitol to Fru IEA Canis familiaris 29105 R-CFA-5661217 https://reactome.org/PathwayBrowser/#/R-CFA-5661217 MT1A binds zinc IEA Canis familiaris 29105 R-CFA-5662471 https://reactome.org/PathwayBrowser/#/R-CFA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Canis familiaris 29105 R-CFA-5662606 https://reactome.org/PathwayBrowser/#/R-CFA-5662606 MT3 binds zinc IEA Canis familiaris 29105 R-CFA-5662613 https://reactome.org/PathwayBrowser/#/R-CFA-5662613 MT3 exchanges zinc for copper IEA Canis familiaris 29105 R-CFA-5662660 https://reactome.org/PathwayBrowser/#/R-CFA-5662660 Dopachrome is transformed to DHICA by DCT IEA Canis familiaris 29105 R-CFA-5682586 https://reactome.org/PathwayBrowser/#/R-CFA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Canis familiaris 29105 R-CFA-5682598 https://reactome.org/PathwayBrowser/#/R-CFA-5682598 ATM phosphorylates HERC2 IEA Canis familiaris 29105 R-CFA-5682629 https://reactome.org/PathwayBrowser/#/R-CFA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Canis familiaris 29105 R-CFA-5682858 https://reactome.org/PathwayBrowser/#/R-CFA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Canis familiaris 29105 R-CFA-5682863 https://reactome.org/PathwayBrowser/#/R-CFA-5682863 RNF168 binds DNA DSBs IEA Canis familiaris 29105 R-CFA-5683077 https://reactome.org/PathwayBrowser/#/R-CFA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Canis familiaris 29105 R-CFA-5683384 https://reactome.org/PathwayBrowser/#/R-CFA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Canis familiaris 29105 R-CFA-5683385 https://reactome.org/PathwayBrowser/#/R-CFA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Canis familiaris 29105 R-CFA-5683405 https://reactome.org/PathwayBrowser/#/R-CFA-5683405 PPP5C dephosphorylates TP53BP1 IEA Canis familiaris 29105 R-CFA-5683425 https://reactome.org/PathwayBrowser/#/R-CFA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Canis familiaris 29105 R-CFA-5683735 https://reactome.org/PathwayBrowser/#/R-CFA-5683735 CHEK2 is recruited to DNA DSBs IEA Canis familiaris 29105 R-CFA-5683801 https://reactome.org/PathwayBrowser/#/R-CFA-5683801 CHEK2 phosphorylates BRCA1 IEA Canis familiaris 29105 R-CFA-5686685 https://reactome.org/PathwayBrowser/#/R-CFA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Canis familiaris 29105 R-CFA-5686704 https://reactome.org/PathwayBrowser/#/R-CFA-5686704 Activated ATM phosphorylates DCLRE1C IEA Canis familiaris 29105 R-CFA-5686900 https://reactome.org/PathwayBrowser/#/R-CFA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Canis familiaris 29105 R-CFA-5688276 https://reactome.org/PathwayBrowser/#/R-CFA-5688276 SIRT4 transfers ADPRib to GLUD IEA Canis familiaris 29105 R-CFA-5688289 https://reactome.org/PathwayBrowser/#/R-CFA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Canis familiaris 29105 R-CFA-5691507 https://reactome.org/PathwayBrowser/#/R-CFA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Canis familiaris 29105 R-CFA-5692237 https://reactome.org/PathwayBrowser/#/R-CFA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Canis familiaris 29105 R-CFA-5693551 https://reactome.org/PathwayBrowser/#/R-CFA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Canis familiaris 29105 R-CFA-5693566 https://reactome.org/PathwayBrowser/#/R-CFA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Canis familiaris 29105 R-CFA-5694071 https://reactome.org/PathwayBrowser/#/R-CFA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Canis familiaris 29105 R-CFA-5694082 https://reactome.org/PathwayBrowser/#/R-CFA-5694082 XK:KEL:Zn2+ cleaves EDN3 IEA Canis familiaris 29105 R-CFA-5696838 https://reactome.org/PathwayBrowser/#/R-CFA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Canis familiaris 29105 R-CFA-6783221 https://reactome.org/PathwayBrowser/#/R-CFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Canis familiaris 29105 R-CFA-6789072 https://reactome.org/PathwayBrowser/#/R-CFA-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Canis familiaris 29105 R-CFA-6798474 https://reactome.org/PathwayBrowser/#/R-CFA-6798474 S100A8:S100A9 binds Zn2+ IEA Canis familiaris 29105 R-CFA-6799545 https://reactome.org/PathwayBrowser/#/R-CFA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Canis familiaris 29105 R-CFA-6799977 https://reactome.org/PathwayBrowser/#/R-CFA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Canis familiaris 29105 R-CFA-69891 https://reactome.org/PathwayBrowser/#/R-CFA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Canis familiaris 29105 R-CFA-71707 https://reactome.org/PathwayBrowser/#/R-CFA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Canis familiaris 29105 R-CFA-73589 https://reactome.org/PathwayBrowser/#/R-CFA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Canis familiaris 29105 R-CFA-73591 https://reactome.org/PathwayBrowser/#/R-CFA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Canis familiaris 29105 R-CFA-73608 https://reactome.org/PathwayBrowser/#/R-CFA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Canis familiaris 29105 R-CFA-73618 https://reactome.org/PathwayBrowser/#/R-CFA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Canis familiaris 29105 R-CFA-73620 https://reactome.org/PathwayBrowser/#/R-CFA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Canis familiaris 29105 R-CFA-74255 https://reactome.org/PathwayBrowser/#/R-CFA-74255 Guanine + H2O => Xanthine + NH4+ IEA Canis familiaris 29105 R-CFA-74730 https://reactome.org/PathwayBrowser/#/R-CFA-74730 Insulin degradation IEA Canis familiaris 29105 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 29105 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 29105 R-CFA-880007 https://reactome.org/PathwayBrowser/#/R-CFA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Canis familiaris 29105 R-CFA-8853686 https://reactome.org/PathwayBrowser/#/R-CFA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Canis familiaris 29105 R-CFA-8866601 https://reactome.org/PathwayBrowser/#/R-CFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Canis familiaris 29105 R-CFA-8867344 https://reactome.org/PathwayBrowser/#/R-CFA-8867344 OMA1 hydrolyses OPA1 IEA Canis familiaris 29105 R-CFA-8878787 https://reactome.org/PathwayBrowser/#/R-CFA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Canis familiaris 29105 R-CFA-8940070 https://reactome.org/PathwayBrowser/#/R-CFA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Canis familiaris 29105 R-CFA-8940074 https://reactome.org/PathwayBrowser/#/R-CFA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Canis familiaris 29105 R-CFA-8949649 https://reactome.org/PathwayBrowser/#/R-CFA-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) IEA Canis familiaris 29105 R-CFA-8949659 https://reactome.org/PathwayBrowser/#/R-CFA-8949659 AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU IEA Canis familiaris 29105 R-CFA-8949661 https://reactome.org/PathwayBrowser/#/R-CFA-8949661 C2orf47:AFG3L2 binds the transit peptide of SMDT1 IEA Canis familiaris 29105 R-CFA-8949668 https://reactome.org/PathwayBrowser/#/R-CFA-8949668 YME1L1 proteolyzes unassembled proSMDT1 IEA Canis familiaris 29105 R-CFA-8951723 https://reactome.org/PathwayBrowser/#/R-CFA-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Canis familiaris 29105 R-CFA-9018862 https://reactome.org/PathwayBrowser/#/R-CFA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Canis familiaris 29105 R-CFA-9018877 https://reactome.org/PathwayBrowser/#/R-CFA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Canis familiaris 29105 R-CFA-9020252 https://reactome.org/PathwayBrowser/#/R-CFA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Canis familiaris 29105 R-CFA-9020253 https://reactome.org/PathwayBrowser/#/R-CFA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Canis familiaris 29105 R-CFA-9020257 https://reactome.org/PathwayBrowser/#/R-CFA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Canis familiaris 29105 R-CFA-9020258 https://reactome.org/PathwayBrowser/#/R-CFA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Canis familiaris 29105 R-CFA-9020270 https://reactome.org/PathwayBrowser/#/R-CFA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Canis familiaris 29105 R-CFA-9024890 https://reactome.org/PathwayBrowser/#/R-CFA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Canis familiaris 29105 R-CFA-947514 https://reactome.org/PathwayBrowser/#/R-CFA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Canis familiaris 29105 R-CFA-964958 https://reactome.org/PathwayBrowser/#/R-CFA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Canis familiaris 29105 R-CFA-964962 https://reactome.org/PathwayBrowser/#/R-CFA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Canis familiaris 29105 R-CFA-964970 https://reactome.org/PathwayBrowser/#/R-CFA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Canis familiaris 29105 R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 29105 R-CFA-9727607 https://reactome.org/PathwayBrowser/#/R-CFA-9727607 MME:Zn2+ binds sacubitrilat IEA Canis familiaris 29105 R-CFA-9731661 https://reactome.org/PathwayBrowser/#/R-CFA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Canis familiaris 29105 R-CFA-9753944 https://reactome.org/PathwayBrowser/#/R-CFA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Canis familiaris 29105 R-CFA-975814 https://reactome.org/PathwayBrowser/#/R-CFA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Canis familiaris 29105 R-CFA-976991 https://reactome.org/PathwayBrowser/#/R-CFA-976991 Prolactin receptor ligands bind the prolactin receptor IEA Canis familiaris 29105 R-CFA-9820566 https://reactome.org/PathwayBrowser/#/R-CFA-9820566 ZnT5 transports zinc into the golgi apparatus IEA Canis familiaris 29105 R-CFA-982810 https://reactome.org/PathwayBrowser/#/R-CFA-982810 JAK2 phosphorylation IEA Canis familiaris 29105 R-CFA-9838627 https://reactome.org/PathwayBrowser/#/R-CFA-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Canis familiaris 29105 R-CFA-9839053 https://reactome.org/PathwayBrowser/#/R-CFA-9839053 AFG3L2:SPG7 binds SMDT1 (EMRE) IEA Canis familiaris 29105 R-CFA-9839059 https://reactome.org/PathwayBrowser/#/R-CFA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Canis familiaris 29105 R-CFA-9839105 https://reactome.org/PathwayBrowser/#/R-CFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Canis familiaris 29105 R-CFA-9839113 https://reactome.org/PathwayBrowser/#/R-CFA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Canis familiaris 29105 R-CFA-9839149 https://reactome.org/PathwayBrowser/#/R-CFA-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Canis familiaris 29105 R-CFA-9840408 https://reactome.org/PathwayBrowser/#/R-CFA-9840408 OMA1 cleaves DELE1 IEA Canis familiaris 29105 R-CFA-9840564 https://reactome.org/PathwayBrowser/#/R-CFA-9840564 OMA1 hydrolyzes YME1L1 IEA Canis familiaris 29105 R-CFA-9854463 https://reactome.org/PathwayBrowser/#/R-CFA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Canis familiaris 29105 R-CFA-9861626 https://reactome.org/PathwayBrowser/#/R-CFA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Canis familiaris 29105 R-DDI-1474184 https://reactome.org/PathwayBrowser/#/R-DDI-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Dictyostelium discoideum 29105 R-DDI-1497784 https://reactome.org/PathwayBrowser/#/R-DDI-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Dictyostelium discoideum 29105 R-DDI-1497796 https://reactome.org/PathwayBrowser/#/R-DDI-1497796 BH2 binding can lead to eNOS uncoupling IEA Dictyostelium discoideum 29105 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 29105 R-DDI-174374 https://reactome.org/PathwayBrowser/#/R-DDI-174374 MTR transfers CH3 from MeCbl to HCYS IEA Dictyostelium discoideum 29105 R-DDI-189439 https://reactome.org/PathwayBrowser/#/R-DDI-189439 ALAD condenses 2 dALAs to form PBG IEA Dictyostelium discoideum 29105 R-DDI-197198 https://reactome.org/PathwayBrowser/#/R-DDI-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Dictyostelium discoideum 29105 R-DDI-200512 https://reactome.org/PathwayBrowser/#/R-DDI-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 29105 R-DDI-202111 https://reactome.org/PathwayBrowser/#/R-DDI-202111 AKT1 phosphorylates eNOS IEA Dictyostelium discoideum 29105 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 29105 R-DDI-202132 https://reactome.org/PathwayBrowser/#/R-DDI-202132 depalmitoylated eNOS translocates from plasma membrane IEA Dictyostelium discoideum 29105 R-DDI-202137 https://reactome.org/PathwayBrowser/#/R-DDI-202137 AKT1 binds eNOS complex via HSP90 IEA Dictyostelium discoideum 29105 R-DDI-203553 https://reactome.org/PathwayBrowser/#/R-DDI-203553 eNOS binds NOSIP IEA Dictyostelium discoideum 29105 R-DDI-203613 https://reactome.org/PathwayBrowser/#/R-DDI-203613 depalmitoylation of eNOS IEA Dictyostelium discoideum 29105 R-DDI-203680 https://reactome.org/PathwayBrowser/#/R-DDI-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Dictyostelium discoideum 29105 R-DDI-203700 https://reactome.org/PathwayBrowser/#/R-DDI-203700 eNOS translocation from Golgi to Caveolae IEA Dictyostelium discoideum 29105 R-DDI-2162078 https://reactome.org/PathwayBrowser/#/R-DDI-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Dictyostelium discoideum 29105 R-DDI-266072 https://reactome.org/PathwayBrowser/#/R-DDI-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Dictyostelium discoideum 29105 R-DDI-2730867 https://reactome.org/PathwayBrowser/#/R-DDI-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Dictyostelium discoideum 29105 R-DDI-2730872 https://reactome.org/PathwayBrowser/#/R-DDI-2730872 Activation of Calcineurin IEA Dictyostelium discoideum 29105 R-DDI-3149518 https://reactome.org/PathwayBrowser/#/R-DDI-3149518 MTRR reduces cob(II)alamin to meCbl IEA Dictyostelium discoideum 29105 R-DDI-3149539 https://reactome.org/PathwayBrowser/#/R-DDI-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Dictyostelium discoideum 29105 R-DDI-3299682 https://reactome.org/PathwayBrowser/#/R-DDI-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Dictyostelium discoideum 29105 R-DDI-3299691 https://reactome.org/PathwayBrowser/#/R-DDI-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Dictyostelium discoideum 29105 R-DDI-3299753 https://reactome.org/PathwayBrowser/#/R-DDI-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Dictyostelium discoideum 29105 R-DDI-3697860 https://reactome.org/PathwayBrowser/#/R-DDI-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Dictyostelium discoideum 29105 R-DDI-3777112 https://reactome.org/PathwayBrowser/#/R-DDI-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Dictyostelium discoideum 29105 R-DDI-428262 https://reactome.org/PathwayBrowser/#/R-DDI-428262 ACER3 hydrolyzes phytoceramide IEA Dictyostelium discoideum 29105 R-DDI-435171 https://reactome.org/PathwayBrowser/#/R-DDI-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Dictyostelium discoideum 29105 R-DDI-435366 https://reactome.org/PathwayBrowser/#/R-DDI-435366 ZnT1 mediates the efflux of zinc from the cell IEA Dictyostelium discoideum 29105 R-DDI-437085 https://reactome.org/PathwayBrowser/#/R-DDI-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Dictyostelium discoideum 29105 R-DDI-437136 https://reactome.org/PathwayBrowser/#/R-DDI-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Dictyostelium discoideum 29105 R-DDI-437139 https://reactome.org/PathwayBrowser/#/R-DDI-437139 ZnT8 transports zinc into the Golgi apparatus IEA Dictyostelium discoideum 29105 R-DDI-442422 https://reactome.org/PathwayBrowser/#/R-DDI-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Dictyostelium discoideum 29105 R-DDI-4551465 https://reactome.org/PathwayBrowser/#/R-DDI-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Dictyostelium discoideum 29105 R-DDI-4837364 https://reactome.org/PathwayBrowser/#/R-DDI-4837364 Secretion of SOD3 IEA Dictyostelium discoideum 29105 R-DDI-5362564 https://reactome.org/PathwayBrowser/#/R-DDI-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Dictyostelium discoideum 29105 R-DDI-5433074 https://reactome.org/PathwayBrowser/#/R-DDI-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Dictyostelium discoideum 29105 R-DDI-5662660 https://reactome.org/PathwayBrowser/#/R-DDI-5662660 Dopachrome is transformed to DHICA by DCT IEA Dictyostelium discoideum 29105 R-DDI-5682588 https://reactome.org/PathwayBrowser/#/R-DDI-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Dictyostelium discoideum 29105 R-DDI-5683405 https://reactome.org/PathwayBrowser/#/R-DDI-5683405 PPP5C dephosphorylates TP53BP1 IEA Dictyostelium discoideum 29105 R-DDI-5683425 https://reactome.org/PathwayBrowser/#/R-DDI-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Dictyostelium discoideum 29105 R-DDI-5688289 https://reactome.org/PathwayBrowser/#/R-DDI-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Dictyostelium discoideum 29105 R-DDI-5688294 https://reactome.org/PathwayBrowser/#/R-DDI-5688294 SIRT5 deacetylates Cytochrome C IEA Dictyostelium discoideum 29105 R-DDI-5692237 https://reactome.org/PathwayBrowser/#/R-DDI-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Dictyostelium discoideum 29105 R-DDI-5693346 https://reactome.org/PathwayBrowser/#/R-DDI-5693346 CECRI deaminates Ade-Rib to Ino IEA Dictyostelium discoideum 29105 R-DDI-5693566 https://reactome.org/PathwayBrowser/#/R-DDI-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Dictyostelium discoideum 29105 R-DDI-6783221 https://reactome.org/PathwayBrowser/#/R-DDI-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Dictyostelium discoideum 29105 R-DDI-6788650 https://reactome.org/PathwayBrowser/#/R-DDI-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Dictyostelium discoideum 29105 R-DDI-6799545 https://reactome.org/PathwayBrowser/#/R-DDI-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Dictyostelium discoideum 29105 R-DDI-6799581 https://reactome.org/PathwayBrowser/#/R-DDI-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Dictyostelium discoideum 29105 R-DDI-71707 https://reactome.org/PathwayBrowser/#/R-DDI-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Dictyostelium discoideum 29105 R-DDI-73589 https://reactome.org/PathwayBrowser/#/R-DDI-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Dictyostelium discoideum 29105 R-DDI-73591 https://reactome.org/PathwayBrowser/#/R-DDI-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Dictyostelium discoideum 29105 R-DDI-73608 https://reactome.org/PathwayBrowser/#/R-DDI-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Dictyostelium discoideum 29105 R-DDI-73618 https://reactome.org/PathwayBrowser/#/R-DDI-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Dictyostelium discoideum 29105 R-DDI-73620 https://reactome.org/PathwayBrowser/#/R-DDI-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Dictyostelium discoideum 29105 R-DDI-74255 https://reactome.org/PathwayBrowser/#/R-DDI-74255 Guanine + H2O => Xanthine + NH4+ IEA Dictyostelium discoideum 29105 R-DDI-880007 https://reactome.org/PathwayBrowser/#/R-DDI-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Dictyostelium discoideum 29105 R-DDI-8853686 https://reactome.org/PathwayBrowser/#/R-DDI-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Dictyostelium discoideum 29105 R-DDI-8866601 https://reactome.org/PathwayBrowser/#/R-DDI-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Dictyostelium discoideum 29105 R-DDI-8867344 https://reactome.org/PathwayBrowser/#/R-DDI-8867344 OMA1 hydrolyses OPA1 IEA Dictyostelium discoideum 29105 R-DDI-8951723 https://reactome.org/PathwayBrowser/#/R-DDI-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Dictyostelium discoideum 29105 R-DDI-9018862 https://reactome.org/PathwayBrowser/#/R-DDI-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Dictyostelium discoideum 29105 R-DDI-9018877 https://reactome.org/PathwayBrowser/#/R-DDI-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Dictyostelium discoideum 29105 R-DDI-9020252 https://reactome.org/PathwayBrowser/#/R-DDI-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Dictyostelium discoideum 29105 R-DDI-9020253 https://reactome.org/PathwayBrowser/#/R-DDI-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Dictyostelium discoideum 29105 R-DDI-9020257 https://reactome.org/PathwayBrowser/#/R-DDI-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Dictyostelium discoideum 29105 R-DDI-9020258 https://reactome.org/PathwayBrowser/#/R-DDI-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Dictyostelium discoideum 29105 R-DDI-9020270 https://reactome.org/PathwayBrowser/#/R-DDI-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Dictyostelium discoideum 29105 R-DDI-9024890 https://reactome.org/PathwayBrowser/#/R-DDI-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Dictyostelium discoideum 29105 R-DDI-947514 https://reactome.org/PathwayBrowser/#/R-DDI-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Dictyostelium discoideum 29105 R-DDI-964958 https://reactome.org/PathwayBrowser/#/R-DDI-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Dictyostelium discoideum 29105 R-DDI-964962 https://reactome.org/PathwayBrowser/#/R-DDI-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Dictyostelium discoideum 29105 R-DDI-964970 https://reactome.org/PathwayBrowser/#/R-DDI-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Dictyostelium discoideum 29105 R-DDI-9753944 https://reactome.org/PathwayBrowser/#/R-DDI-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Dictyostelium discoideum 29105 R-DDI-9820566 https://reactome.org/PathwayBrowser/#/R-DDI-9820566 ZnT5 transports zinc into the golgi apparatus IEA Dictyostelium discoideum 29105 R-DDI-9838627 https://reactome.org/PathwayBrowser/#/R-DDI-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Dictyostelium discoideum 29105 R-DDI-9839105 https://reactome.org/PathwayBrowser/#/R-DDI-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Dictyostelium discoideum 29105 R-DDI-9839113 https://reactome.org/PathwayBrowser/#/R-DDI-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Dictyostelium discoideum 29105 R-DDI-9839149 https://reactome.org/PathwayBrowser/#/R-DDI-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Dictyostelium discoideum 29105 R-DDI-9840564 https://reactome.org/PathwayBrowser/#/R-DDI-9840564 OMA1 hydrolyzes YME1L1 IEA Dictyostelium discoideum 29105 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 29105 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 29105 R-DME-1237045 https://reactome.org/PathwayBrowser/#/R-DME-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Drosophila melanogaster 29105 R-DME-1237047 https://reactome.org/PathwayBrowser/#/R-DME-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Drosophila melanogaster 29105 R-DME-1237059 https://reactome.org/PathwayBrowser/#/R-DME-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Drosophila melanogaster 29105 R-DME-1237081 https://reactome.org/PathwayBrowser/#/R-DME-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Drosophila melanogaster 29105 R-DME-1474184 https://reactome.org/PathwayBrowser/#/R-DME-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Drosophila melanogaster 29105 R-DME-1475017 https://reactome.org/PathwayBrowser/#/R-DME-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Drosophila melanogaster 29105 R-DME-1475022 https://reactome.org/PathwayBrowser/#/R-DME-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Drosophila melanogaster 29105 R-DME-1475025 https://reactome.org/PathwayBrowser/#/R-DME-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Drosophila melanogaster 29105 R-DME-1475026 https://reactome.org/PathwayBrowser/#/R-DME-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Drosophila melanogaster 29105 R-DME-1475028 https://reactome.org/PathwayBrowser/#/R-DME-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Drosophila melanogaster 29105 R-DME-1475032 https://reactome.org/PathwayBrowser/#/R-DME-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Drosophila melanogaster 29105 R-DME-1475422 https://reactome.org/PathwayBrowser/#/R-DME-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Drosophila melanogaster 29105 R-DME-1475435 https://reactome.org/PathwayBrowser/#/R-DME-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Drosophila melanogaster 29105 R-DME-1475436 https://reactome.org/PathwayBrowser/#/R-DME-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Drosophila melanogaster 29105 R-DME-1497784 https://reactome.org/PathwayBrowser/#/R-DME-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Drosophila melanogaster 29105 R-DME-1497796 https://reactome.org/PathwayBrowser/#/R-DME-1497796 BH2 binding can lead to eNOS uncoupling IEA Drosophila melanogaster 29105 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 29105 R-DME-1614605 https://reactome.org/PathwayBrowser/#/R-DME-1614605 Persulfide sulfur is dioxygenated IEA Drosophila melanogaster 29105 R-DME-189439 https://reactome.org/PathwayBrowser/#/R-DME-189439 ALAD condenses 2 dALAs to form PBG IEA Drosophila melanogaster 29105 R-DME-197198 https://reactome.org/PathwayBrowser/#/R-DME-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 29105 R-DME-200512 https://reactome.org/PathwayBrowser/#/R-DME-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 29105 R-DME-202111 https://reactome.org/PathwayBrowser/#/R-DME-202111 AKT1 phosphorylates eNOS IEA Drosophila melanogaster 29105 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 29105 R-DME-202132 https://reactome.org/PathwayBrowser/#/R-DME-202132 depalmitoylated eNOS translocates from plasma membrane IEA Drosophila melanogaster 29105 R-DME-202137 https://reactome.org/PathwayBrowser/#/R-DME-202137 AKT1 binds eNOS complex via HSP90 IEA Drosophila melanogaster 29105 R-DME-2022368 https://reactome.org/PathwayBrowser/#/R-DME-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Drosophila melanogaster 29105 R-DME-2022396 https://reactome.org/PathwayBrowser/#/R-DME-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Drosophila melanogaster 29105 R-DME-2022398 https://reactome.org/PathwayBrowser/#/R-DME-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Drosophila melanogaster 29105 R-DME-2022399 https://reactome.org/PathwayBrowser/#/R-DME-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Drosophila melanogaster 29105 R-DME-2022405 https://reactome.org/PathwayBrowser/#/R-DME-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 29105 R-DME-2025890 https://reactome.org/PathwayBrowser/#/R-DME-2025890 Calcineurin binds NFATC1,2,3 IEA Drosophila melanogaster 29105 R-DME-2028294 https://reactome.org/PathwayBrowser/#/R-DME-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Drosophila melanogaster 29105 R-DME-203553 https://reactome.org/PathwayBrowser/#/R-DME-203553 eNOS binds NOSIP IEA Drosophila melanogaster 29105 R-DME-203613 https://reactome.org/PathwayBrowser/#/R-DME-203613 depalmitoylation of eNOS IEA Drosophila melanogaster 29105 R-DME-203680 https://reactome.org/PathwayBrowser/#/R-DME-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Drosophila melanogaster 29105 R-DME-203700 https://reactome.org/PathwayBrowser/#/R-DME-203700 eNOS translocation from Golgi to Caveolae IEA Drosophila melanogaster 29105 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 29105 R-DME-2161187 https://reactome.org/PathwayBrowser/#/R-DME-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Drosophila melanogaster 29105 R-DME-2161195 https://reactome.org/PathwayBrowser/#/R-DME-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Drosophila melanogaster 29105 R-DME-2162078 https://reactome.org/PathwayBrowser/#/R-DME-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Drosophila melanogaster 29105 R-DME-265682 https://reactome.org/PathwayBrowser/#/R-DME-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Drosophila melanogaster 29105 R-DME-266012 https://reactome.org/PathwayBrowser/#/R-DME-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Drosophila melanogaster 29105 R-DME-266072 https://reactome.org/PathwayBrowser/#/R-DME-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Drosophila melanogaster 29105 R-DME-2730849 https://reactome.org/PathwayBrowser/#/R-DME-2730849 Calcineurin binds and dephosphorylates NFAT IEA Drosophila melanogaster 29105 R-DME-2730867 https://reactome.org/PathwayBrowser/#/R-DME-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Drosophila melanogaster 29105 R-DME-2730872 https://reactome.org/PathwayBrowser/#/R-DME-2730872 Activation of Calcineurin IEA Drosophila melanogaster 29105 R-DME-3299691 https://reactome.org/PathwayBrowser/#/R-DME-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Drosophila melanogaster 29105 R-DME-3299753 https://reactome.org/PathwayBrowser/#/R-DME-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Drosophila melanogaster 29105 R-DME-3697860 https://reactome.org/PathwayBrowser/#/R-DME-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Drosophila melanogaster 29105 R-DME-3777112 https://reactome.org/PathwayBrowser/#/R-DME-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Drosophila melanogaster 29105 R-DME-435171 https://reactome.org/PathwayBrowser/#/R-DME-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Drosophila melanogaster 29105 R-DME-435366 https://reactome.org/PathwayBrowser/#/R-DME-435366 ZnT1 mediates the efflux of zinc from the cell IEA Drosophila melanogaster 29105 R-DME-437136 https://reactome.org/PathwayBrowser/#/R-DME-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Drosophila melanogaster 29105 R-DME-437139 https://reactome.org/PathwayBrowser/#/R-DME-437139 ZnT8 transports zinc into the Golgi apparatus IEA Drosophila melanogaster 29105 R-DME-442317 https://reactome.org/PathwayBrowser/#/R-DME-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Drosophila melanogaster 29105 R-DME-442393 https://reactome.org/PathwayBrowser/#/R-DME-442393 ZIP7 mediates zinc efflux from the endoplasmic reticulum IEA Drosophila melanogaster 29105 R-DME-442422 https://reactome.org/PathwayBrowser/#/R-DME-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Drosophila melanogaster 29105 R-DME-4551451 https://reactome.org/PathwayBrowser/#/R-DME-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Drosophila melanogaster 29105 R-DME-4551465 https://reactome.org/PathwayBrowser/#/R-DME-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Drosophila melanogaster 29105 R-DME-5362564 https://reactome.org/PathwayBrowser/#/R-DME-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Drosophila melanogaster 29105 R-DME-5433067 https://reactome.org/PathwayBrowser/#/R-DME-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Drosophila melanogaster 29105 R-DME-5433074 https://reactome.org/PathwayBrowser/#/R-DME-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Drosophila melanogaster 29105 R-DME-5652195 https://reactome.org/PathwayBrowser/#/R-DME-5652195 SORD oxidizes D-sorbitol to Fru IEA Drosophila melanogaster 29105 R-DME-5662471 https://reactome.org/PathwayBrowser/#/R-DME-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Drosophila melanogaster 29105 R-DME-5682586 https://reactome.org/PathwayBrowser/#/R-DME-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Drosophila melanogaster 29105 R-DME-5682598 https://reactome.org/PathwayBrowser/#/R-DME-5682598 ATM phosphorylates HERC2 IEA Drosophila melanogaster 29105 R-DME-5682629 https://reactome.org/PathwayBrowser/#/R-DME-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Drosophila melanogaster 29105 R-DME-5682858 https://reactome.org/PathwayBrowser/#/R-DME-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Drosophila melanogaster 29105 R-DME-5683077 https://reactome.org/PathwayBrowser/#/R-DME-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Drosophila melanogaster 29105 R-DME-5688276 https://reactome.org/PathwayBrowser/#/R-DME-5688276 SIRT4 transfers ADPRib to GLUD IEA Drosophila melanogaster 29105 R-DME-5692237 https://reactome.org/PathwayBrowser/#/R-DME-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Drosophila melanogaster 29105 R-DME-5693346 https://reactome.org/PathwayBrowser/#/R-DME-5693346 CECRI deaminates Ade-Rib to Ino IEA Drosophila melanogaster 29105 R-DME-5694071 https://reactome.org/PathwayBrowser/#/R-DME-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Drosophila melanogaster 29105 R-DME-6783221 https://reactome.org/PathwayBrowser/#/R-DME-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Drosophila melanogaster 29105 R-DME-6788650 https://reactome.org/PathwayBrowser/#/R-DME-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Drosophila melanogaster 29105 R-DME-6789072 https://reactome.org/PathwayBrowser/#/R-DME-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Drosophila melanogaster 29105 R-DME-6799581 https://reactome.org/PathwayBrowser/#/R-DME-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Drosophila melanogaster 29105 R-DME-6799959 https://reactome.org/PathwayBrowser/#/R-DME-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Drosophila melanogaster 29105 R-DME-6799977 https://reactome.org/PathwayBrowser/#/R-DME-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Drosophila melanogaster 29105 R-DME-71707 https://reactome.org/PathwayBrowser/#/R-DME-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Drosophila melanogaster 29105 R-DME-73589 https://reactome.org/PathwayBrowser/#/R-DME-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Drosophila melanogaster 29105 R-DME-73591 https://reactome.org/PathwayBrowser/#/R-DME-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Drosophila melanogaster 29105 R-DME-73608 https://reactome.org/PathwayBrowser/#/R-DME-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Drosophila melanogaster 29105 R-DME-73618 https://reactome.org/PathwayBrowser/#/R-DME-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Drosophila melanogaster 29105 R-DME-73620 https://reactome.org/PathwayBrowser/#/R-DME-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Drosophila melanogaster 29105 R-DME-74255 https://reactome.org/PathwayBrowser/#/R-DME-74255 Guanine + H2O => Xanthine + NH4+ IEA Drosophila melanogaster 29105 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 29105 R-DME-880007 https://reactome.org/PathwayBrowser/#/R-DME-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Drosophila melanogaster 29105 R-DME-8853686 https://reactome.org/PathwayBrowser/#/R-DME-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Drosophila melanogaster 29105 R-DME-8866601 https://reactome.org/PathwayBrowser/#/R-DME-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Drosophila melanogaster 29105 R-DME-8878787 https://reactome.org/PathwayBrowser/#/R-DME-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Drosophila melanogaster 29105 R-DME-8940070 https://reactome.org/PathwayBrowser/#/R-DME-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Drosophila melanogaster 29105 R-DME-8940074 https://reactome.org/PathwayBrowser/#/R-DME-8940074 NT5E:Zn2+ hydrolyses NMN IEA Drosophila melanogaster 29105 R-DME-8949649 https://reactome.org/PathwayBrowser/#/R-DME-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) IEA Drosophila melanogaster 29105 R-DME-8949659 https://reactome.org/PathwayBrowser/#/R-DME-8949659 AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU IEA Drosophila melanogaster 29105 R-DME-8949661 https://reactome.org/PathwayBrowser/#/R-DME-8949661 C2orf47:AFG3L2 binds the transit peptide of SMDT1 IEA Drosophila melanogaster 29105 R-DME-8951723 https://reactome.org/PathwayBrowser/#/R-DME-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Drosophila melanogaster 29105 R-DME-9018862 https://reactome.org/PathwayBrowser/#/R-DME-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Drosophila melanogaster 29105 R-DME-9018877 https://reactome.org/PathwayBrowser/#/R-DME-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Drosophila melanogaster 29105 R-DME-9020252 https://reactome.org/PathwayBrowser/#/R-DME-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Drosophila melanogaster 29105 R-DME-9020253 https://reactome.org/PathwayBrowser/#/R-DME-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Drosophila melanogaster 29105 R-DME-9020257 https://reactome.org/PathwayBrowser/#/R-DME-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Drosophila melanogaster 29105 R-DME-9020258 https://reactome.org/PathwayBrowser/#/R-DME-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Drosophila melanogaster 29105 R-DME-9020270 https://reactome.org/PathwayBrowser/#/R-DME-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Drosophila melanogaster 29105 R-DME-9024890 https://reactome.org/PathwayBrowser/#/R-DME-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Drosophila melanogaster 29105 R-DME-947514 https://reactome.org/PathwayBrowser/#/R-DME-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Drosophila melanogaster 29105 R-DME-9610152 https://reactome.org/PathwayBrowser/#/R-DME-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Drosophila melanogaster 29105 R-DME-9610153 https://reactome.org/PathwayBrowser/#/R-DME-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Drosophila melanogaster 29105 R-DME-9610154 https://reactome.org/PathwayBrowser/#/R-DME-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Drosophila melanogaster 29105 R-DME-9610156 https://reactome.org/PathwayBrowser/#/R-DME-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Drosophila melanogaster 29105 R-DME-9610163 https://reactome.org/PathwayBrowser/#/R-DME-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Drosophila melanogaster 29105 R-DME-9647977 https://reactome.org/PathwayBrowser/#/R-DME-9647977 ICMT methylates S-Farn RAS proteins IEA Drosophila melanogaster 29105 R-DME-964958 https://reactome.org/PathwayBrowser/#/R-DME-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Drosophila melanogaster 29105 R-DME-964962 https://reactome.org/PathwayBrowser/#/R-DME-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Drosophila melanogaster 29105 R-DME-964970 https://reactome.org/PathwayBrowser/#/R-DME-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Drosophila melanogaster 29105 R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 29105 R-DME-9727607 https://reactome.org/PathwayBrowser/#/R-DME-9727607 MME:Zn2+ binds sacubitrilat IEA Drosophila melanogaster 29105 R-DME-9731661 https://reactome.org/PathwayBrowser/#/R-DME-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Drosophila melanogaster 29105 R-DME-9753944 https://reactome.org/PathwayBrowser/#/R-DME-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Drosophila melanogaster 29105 R-DME-975814 https://reactome.org/PathwayBrowser/#/R-DME-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Drosophila melanogaster 29105 R-DME-9838627 https://reactome.org/PathwayBrowser/#/R-DME-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Drosophila melanogaster 29105 R-DME-9839053 https://reactome.org/PathwayBrowser/#/R-DME-9839053 AFG3L2:SPG7 binds SMDT1 (EMRE) IEA Drosophila melanogaster 29105 R-DME-9839059 https://reactome.org/PathwayBrowser/#/R-DME-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Drosophila melanogaster 29105 R-DME-9839105 https://reactome.org/PathwayBrowser/#/R-DME-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Drosophila melanogaster 29105 R-DME-9839113 https://reactome.org/PathwayBrowser/#/R-DME-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Drosophila melanogaster 29105 R-DME-9839149 https://reactome.org/PathwayBrowser/#/R-DME-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Drosophila melanogaster 29105 R-DME-9861626 https://reactome.org/PathwayBrowser/#/R-DME-9861626 SIRT4 cleaves lipoyl from DLAT IEA Drosophila melanogaster 29105 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 29105 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 29105 R-DRE-1237047 https://reactome.org/PathwayBrowser/#/R-DRE-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Danio rerio 29105 R-DRE-1237059 https://reactome.org/PathwayBrowser/#/R-DRE-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Danio rerio 29105 R-DRE-1474184 https://reactome.org/PathwayBrowser/#/R-DRE-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Danio rerio 29105 R-DRE-1475017 https://reactome.org/PathwayBrowser/#/R-DRE-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Danio rerio 29105 R-DRE-1475022 https://reactome.org/PathwayBrowser/#/R-DRE-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Danio rerio 29105 R-DRE-1475025 https://reactome.org/PathwayBrowser/#/R-DRE-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Danio rerio 29105 R-DRE-1475026 https://reactome.org/PathwayBrowser/#/R-DRE-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Danio rerio 29105 R-DRE-1475028 https://reactome.org/PathwayBrowser/#/R-DRE-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Danio rerio 29105 R-DRE-1475032 https://reactome.org/PathwayBrowser/#/R-DRE-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Danio rerio 29105 R-DRE-1475435 https://reactome.org/PathwayBrowser/#/R-DRE-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Danio rerio 29105 R-DRE-1475436 https://reactome.org/PathwayBrowser/#/R-DRE-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Danio rerio 29105 R-DRE-1614605 https://reactome.org/PathwayBrowser/#/R-DRE-1614605 Persulfide sulfur is dioxygenated IEA Danio rerio 29105 R-DRE-1614654 https://reactome.org/PathwayBrowser/#/R-DRE-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Danio rerio 29105 R-DRE-189384 https://reactome.org/PathwayBrowser/#/R-DRE-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Danio rerio 29105 R-DRE-189439 https://reactome.org/PathwayBrowser/#/R-DRE-189439 ALAD condenses 2 dALAs to form PBG IEA Danio rerio 29105 R-DRE-197198 https://reactome.org/PathwayBrowser/#/R-DRE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Danio rerio 29105 R-DRE-200512 https://reactome.org/PathwayBrowser/#/R-DRE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 29105 R-DRE-2028294 https://reactome.org/PathwayBrowser/#/R-DRE-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Danio rerio 29105 R-DRE-203565 https://reactome.org/PathwayBrowser/#/R-DRE-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Danio rerio 29105 R-DRE-203625 https://reactome.org/PathwayBrowser/#/R-DRE-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Danio rerio 29105 R-DRE-2161187 https://reactome.org/PathwayBrowser/#/R-DRE-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Danio rerio 29105 R-DRE-2161195 https://reactome.org/PathwayBrowser/#/R-DRE-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Danio rerio 29105 R-DRE-2162078 https://reactome.org/PathwayBrowser/#/R-DRE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Danio rerio 29105 R-DRE-264758 https://reactome.org/PathwayBrowser/#/R-DRE-264758 BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 IEA Danio rerio 29105 R-DRE-264976 https://reactome.org/PathwayBrowser/#/R-DRE-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Danio rerio 29105 R-DRE-265153 https://reactome.org/PathwayBrowser/#/R-DRE-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Danio rerio 29105 R-DRE-266072 https://reactome.org/PathwayBrowser/#/R-DRE-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Danio rerio 29105 R-DRE-3299682 https://reactome.org/PathwayBrowser/#/R-DRE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Danio rerio 29105 R-DRE-3299691 https://reactome.org/PathwayBrowser/#/R-DRE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Danio rerio 29105 R-DRE-3777112 https://reactome.org/PathwayBrowser/#/R-DRE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Danio rerio 29105 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 29105 R-DRE-435171 https://reactome.org/PathwayBrowser/#/R-DRE-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Danio rerio 29105 R-DRE-437085 https://reactome.org/PathwayBrowser/#/R-DRE-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Danio rerio 29105 R-DRE-442317 https://reactome.org/PathwayBrowser/#/R-DRE-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Danio rerio 29105 R-DRE-442422 https://reactome.org/PathwayBrowser/#/R-DRE-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Danio rerio 29105 R-DRE-444572 https://reactome.org/PathwayBrowser/#/R-DRE-444572 Zinc is an agonist of GPR39 IEA Danio rerio 29105 R-DRE-4837364 https://reactome.org/PathwayBrowser/#/R-DRE-4837364 Secretion of SOD3 IEA Danio rerio 29105 R-DRE-5362564 https://reactome.org/PathwayBrowser/#/R-DRE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Danio rerio 29105 R-DRE-5661217 https://reactome.org/PathwayBrowser/#/R-DRE-5661217 MT1A binds zinc IEA Danio rerio 29105 R-DRE-5662606 https://reactome.org/PathwayBrowser/#/R-DRE-5662606 MT3 binds zinc IEA Danio rerio 29105 R-DRE-5662613 https://reactome.org/PathwayBrowser/#/R-DRE-5662613 MT3 exchanges zinc for copper IEA Danio rerio 29105 R-DRE-5662660 https://reactome.org/PathwayBrowser/#/R-DRE-5662660 Dopachrome is transformed to DHICA by DCT IEA Danio rerio 29105 R-DRE-5688276 https://reactome.org/PathwayBrowser/#/R-DRE-5688276 SIRT4 transfers ADPRib to GLUD IEA Danio rerio 29105 R-DRE-5688294 https://reactome.org/PathwayBrowser/#/R-DRE-5688294 SIRT5 deacetylates Cytochrome C IEA Danio rerio 29105 R-DRE-5691507 https://reactome.org/PathwayBrowser/#/R-DRE-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Danio rerio 29105 R-DRE-5692237 https://reactome.org/PathwayBrowser/#/R-DRE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Danio rerio 29105 R-DRE-5693346 https://reactome.org/PathwayBrowser/#/R-DRE-5693346 CECRI deaminates Ade-Rib to Ino IEA Danio rerio 29105 R-DRE-5694071 https://reactome.org/PathwayBrowser/#/R-DRE-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Danio rerio 29105 R-DRE-5696838 https://reactome.org/PathwayBrowser/#/R-DRE-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Danio rerio 29105 R-DRE-6783221 https://reactome.org/PathwayBrowser/#/R-DRE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Danio rerio 29105 R-DRE-6788650 https://reactome.org/PathwayBrowser/#/R-DRE-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Danio rerio 29105 R-DRE-6789072 https://reactome.org/PathwayBrowser/#/R-DRE-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Danio rerio 29105 R-DRE-6798474 https://reactome.org/PathwayBrowser/#/R-DRE-6798474 S100A8:S100A9 binds Zn2+ IEA Danio rerio 29105 R-DRE-6798489 https://reactome.org/PathwayBrowser/#/R-DRE-6798489 S100A7 or S100A7A binds Zn2+ IEA Danio rerio 29105 R-DRE-6799959 https://reactome.org/PathwayBrowser/#/R-DRE-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Danio rerio 29105 R-DRE-6799977 https://reactome.org/PathwayBrowser/#/R-DRE-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Danio rerio 29105 R-DRE-71707 https://reactome.org/PathwayBrowser/#/R-DRE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Danio rerio 29105 R-DRE-73589 https://reactome.org/PathwayBrowser/#/R-DRE-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Danio rerio 29105 R-DRE-73591 https://reactome.org/PathwayBrowser/#/R-DRE-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Danio rerio 29105 R-DRE-73608 https://reactome.org/PathwayBrowser/#/R-DRE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Danio rerio 29105 R-DRE-73618 https://reactome.org/PathwayBrowser/#/R-DRE-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Danio rerio 29105 R-DRE-73620 https://reactome.org/PathwayBrowser/#/R-DRE-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Danio rerio 29105 R-DRE-74255 https://reactome.org/PathwayBrowser/#/R-DRE-74255 Guanine + H2O => Xanthine + NH4+ IEA Danio rerio 29105 R-DRE-74730 https://reactome.org/PathwayBrowser/#/R-DRE-74730 Insulin degradation IEA Danio rerio 29105 R-DRE-880007 https://reactome.org/PathwayBrowser/#/R-DRE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Danio rerio 29105 R-DRE-8866601 https://reactome.org/PathwayBrowser/#/R-DRE-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Danio rerio 29105 R-DRE-8867344 https://reactome.org/PathwayBrowser/#/R-DRE-8867344 OMA1 hydrolyses OPA1 IEA Danio rerio 29105 R-DRE-8878787 https://reactome.org/PathwayBrowser/#/R-DRE-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Danio rerio 29105 R-DRE-8940070 https://reactome.org/PathwayBrowser/#/R-DRE-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Danio rerio 29105 R-DRE-8940074 https://reactome.org/PathwayBrowser/#/R-DRE-8940074 NT5E:Zn2+ hydrolyses NMN IEA Danio rerio 29105 R-DRE-9018862 https://reactome.org/PathwayBrowser/#/R-DRE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Danio rerio 29105 R-DRE-9018877 https://reactome.org/PathwayBrowser/#/R-DRE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Danio rerio 29105 R-DRE-9020252 https://reactome.org/PathwayBrowser/#/R-DRE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Danio rerio 29105 R-DRE-9020253 https://reactome.org/PathwayBrowser/#/R-DRE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Danio rerio 29105 R-DRE-9020257 https://reactome.org/PathwayBrowser/#/R-DRE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Danio rerio 29105 R-DRE-9020258 https://reactome.org/PathwayBrowser/#/R-DRE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Danio rerio 29105 R-DRE-9020270 https://reactome.org/PathwayBrowser/#/R-DRE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Danio rerio 29105 R-DRE-9024890 https://reactome.org/PathwayBrowser/#/R-DRE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Danio rerio 29105 R-DRE-947514 https://reactome.org/PathwayBrowser/#/R-DRE-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Danio rerio 29105 R-DRE-9610153 https://reactome.org/PathwayBrowser/#/R-DRE-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Danio rerio 29105 R-DRE-9610156 https://reactome.org/PathwayBrowser/#/R-DRE-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Danio rerio 29105 R-DRE-9638046 https://reactome.org/PathwayBrowser/#/R-DRE-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Danio rerio 29105 R-DRE-9647977 https://reactome.org/PathwayBrowser/#/R-DRE-9647977 ICMT methylates S-Farn RAS proteins IEA Danio rerio 29105 R-DRE-964958 https://reactome.org/PathwayBrowser/#/R-DRE-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Danio rerio 29105 R-DRE-964962 https://reactome.org/PathwayBrowser/#/R-DRE-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Danio rerio 29105 R-DRE-964970 https://reactome.org/PathwayBrowser/#/R-DRE-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Danio rerio 29105 R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 29105 R-DRE-9731661 https://reactome.org/PathwayBrowser/#/R-DRE-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Danio rerio 29105 R-DRE-9820566 https://reactome.org/PathwayBrowser/#/R-DRE-9820566 ZnT5 transports zinc into the golgi apparatus IEA Danio rerio 29105 R-DRE-982810 https://reactome.org/PathwayBrowser/#/R-DRE-982810 JAK2 phosphorylation IEA Danio rerio 29105 R-DRE-9838627 https://reactome.org/PathwayBrowser/#/R-DRE-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Danio rerio 29105 R-DRE-9839105 https://reactome.org/PathwayBrowser/#/R-DRE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Danio rerio 29105 R-DRE-9839113 https://reactome.org/PathwayBrowser/#/R-DRE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Danio rerio 29105 R-DRE-9839149 https://reactome.org/PathwayBrowser/#/R-DRE-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Danio rerio 29105 R-DRE-9840408 https://reactome.org/PathwayBrowser/#/R-DRE-9840408 OMA1 cleaves DELE1 IEA Danio rerio 29105 R-DRE-9861626 https://reactome.org/PathwayBrowser/#/R-DRE-9861626 SIRT4 cleaves lipoyl from DLAT IEA Danio rerio 29105 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 29105 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 29105 R-GGA-1170539 https://reactome.org/PathwayBrowser/#/R-GGA-1170539 Prolactin receptor is internalized IEA Gallus gallus 29105 R-GGA-1237045 https://reactome.org/PathwayBrowser/#/R-GGA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Gallus gallus 29105 R-GGA-1237047 https://reactome.org/PathwayBrowser/#/R-GGA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Gallus gallus 29105 R-GGA-1237059 https://reactome.org/PathwayBrowser/#/R-GGA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Gallus gallus 29105 R-GGA-1237081 https://reactome.org/PathwayBrowser/#/R-GGA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Gallus gallus 29105 R-GGA-1370500 https://reactome.org/PathwayBrowser/#/R-GGA-1370500 PRLR binds SCF beta-TrCP complex IEA Gallus gallus 29105 R-GGA-1370505 https://reactome.org/PathwayBrowser/#/R-GGA-1370505 PRLR is phosphorylated at Ser-349 IEA Gallus gallus 29105 R-GGA-1474184 https://reactome.org/PathwayBrowser/#/R-GGA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Gallus gallus 29105 R-GGA-1475017 https://reactome.org/PathwayBrowser/#/R-GGA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Gallus gallus 29105 R-GGA-1475022 https://reactome.org/PathwayBrowser/#/R-GGA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Gallus gallus 29105 R-GGA-1475025 https://reactome.org/PathwayBrowser/#/R-GGA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Gallus gallus 29105 R-GGA-1475026 https://reactome.org/PathwayBrowser/#/R-GGA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Gallus gallus 29105 R-GGA-1475028 https://reactome.org/PathwayBrowser/#/R-GGA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Gallus gallus 29105 R-GGA-1475032 https://reactome.org/PathwayBrowser/#/R-GGA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Gallus gallus 29105 R-GGA-1475422 https://reactome.org/PathwayBrowser/#/R-GGA-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Gallus gallus 29105 R-GGA-1475435 https://reactome.org/PathwayBrowser/#/R-GGA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Gallus gallus 29105 R-GGA-1475436 https://reactome.org/PathwayBrowser/#/R-GGA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Gallus gallus 29105 R-GGA-1497784 https://reactome.org/PathwayBrowser/#/R-GGA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Gallus gallus 29105 R-GGA-1497796 https://reactome.org/PathwayBrowser/#/R-GGA-1497796 BH2 binding can lead to eNOS uncoupling IEA Gallus gallus 29105 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 29105 R-GGA-158354 https://reactome.org/PathwayBrowser/#/R-GGA-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer IEA Gallus gallus 29105 R-GGA-158941 https://reactome.org/PathwayBrowser/#/R-GGA-158941 plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein IEA Gallus gallus 29105 R-GGA-1614654 https://reactome.org/PathwayBrowser/#/R-GGA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Gallus gallus 29105 R-GGA-1671687 https://reactome.org/PathwayBrowser/#/R-GGA-1671687 PRLR activation IEA Gallus gallus 29105 R-GGA-1675473 https://reactome.org/PathwayBrowser/#/R-GGA-1675473 SH2B binds JAK2 IEA Gallus gallus 29105 R-GGA-174374 https://reactome.org/PathwayBrowser/#/R-GGA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Gallus gallus 29105 R-GGA-189384 https://reactome.org/PathwayBrowser/#/R-GGA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Gallus gallus 29105 R-GGA-189439 https://reactome.org/PathwayBrowser/#/R-GGA-189439 ALAD condenses 2 dALAs to form PBG IEA Gallus gallus 29105 R-GGA-193679 https://reactome.org/PathwayBrowser/#/R-GGA-193679 alpha-secretase cleaves the p75NTR extracellular domain IEA Gallus gallus 29105 R-GGA-197198 https://reactome.org/PathwayBrowser/#/R-GGA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Gallus gallus 29105 R-GGA-200512 https://reactome.org/PathwayBrowser/#/R-GGA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 29105 R-GGA-202110 https://reactome.org/PathwayBrowser/#/R-GGA-202110 eNOS:Caveolin-1 complex binds to CaM IEA Gallus gallus 29105 R-GGA-202111 https://reactome.org/PathwayBrowser/#/R-GGA-202111 AKT1 phosphorylates eNOS IEA Gallus gallus 29105 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 29105 R-GGA-202129 https://reactome.org/PathwayBrowser/#/R-GGA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Gallus gallus 29105 R-GGA-202132 https://reactome.org/PathwayBrowser/#/R-GGA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Gallus gallus 29105 R-GGA-202137 https://reactome.org/PathwayBrowser/#/R-GGA-202137 AKT1 binds eNOS complex via HSP90 IEA Gallus gallus 29105 R-GGA-202144 https://reactome.org/PathwayBrowser/#/R-GGA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Gallus gallus 29105 R-GGA-2022368 https://reactome.org/PathwayBrowser/#/R-GGA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Gallus gallus 29105 R-GGA-2022378 https://reactome.org/PathwayBrowser/#/R-GGA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Gallus gallus 29105 R-GGA-2022379 https://reactome.org/PathwayBrowser/#/R-GGA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Gallus gallus 29105 R-GGA-2022396 https://reactome.org/PathwayBrowser/#/R-GGA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Gallus gallus 29105 R-GGA-2022398 https://reactome.org/PathwayBrowser/#/R-GGA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Gallus gallus 29105 R-GGA-2022399 https://reactome.org/PathwayBrowser/#/R-GGA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Gallus gallus 29105 R-GGA-2022405 https://reactome.org/PathwayBrowser/#/R-GGA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 29105 R-GGA-2025890 https://reactome.org/PathwayBrowser/#/R-GGA-2025890 Calcineurin binds NFATC1,2,3 IEA Gallus gallus 29105 R-GGA-203565 https://reactome.org/PathwayBrowser/#/R-GGA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Gallus gallus 29105 R-GGA-203613 https://reactome.org/PathwayBrowser/#/R-GGA-203613 depalmitoylation of eNOS IEA Gallus gallus 29105 R-GGA-203625 https://reactome.org/PathwayBrowser/#/R-GGA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Gallus gallus 29105 R-GGA-203700 https://reactome.org/PathwayBrowser/#/R-GGA-203700 eNOS translocation from Golgi to Caveolae IEA Gallus gallus 29105 R-GGA-203712 https://reactome.org/PathwayBrowser/#/R-GGA-203712 eNOS associates with Caveolin-1 IEA Gallus gallus 29105 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 29105 R-GGA-2161187 https://reactome.org/PathwayBrowser/#/R-GGA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Gallus gallus 29105 R-GGA-2161195 https://reactome.org/PathwayBrowser/#/R-GGA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Gallus gallus 29105 R-GGA-2162078 https://reactome.org/PathwayBrowser/#/R-GGA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Gallus gallus 29105 R-GGA-264976 https://reactome.org/PathwayBrowser/#/R-GGA-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Gallus gallus 29105 R-GGA-265153 https://reactome.org/PathwayBrowser/#/R-GGA-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Gallus gallus 29105 R-GGA-265682 https://reactome.org/PathwayBrowser/#/R-GGA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Gallus gallus 29105 R-GGA-266012 https://reactome.org/PathwayBrowser/#/R-GGA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Gallus gallus 29105 R-GGA-266072 https://reactome.org/PathwayBrowser/#/R-GGA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Gallus gallus 29105 R-GGA-2730849 https://reactome.org/PathwayBrowser/#/R-GGA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Gallus gallus 29105 R-GGA-2730867 https://reactome.org/PathwayBrowser/#/R-GGA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Gallus gallus 29105 R-GGA-2730872 https://reactome.org/PathwayBrowser/#/R-GGA-2730872 Activation of Calcineurin IEA Gallus gallus 29105 R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus 29105 R-GGA-3149539 https://reactome.org/PathwayBrowser/#/R-GGA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Gallus gallus 29105 R-GGA-3204318 https://reactome.org/PathwayBrowser/#/R-GGA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Gallus gallus 29105 R-GGA-3299682 https://reactome.org/PathwayBrowser/#/R-GGA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Gallus gallus 29105 R-GGA-3299691 https://reactome.org/PathwayBrowser/#/R-GGA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Gallus gallus 29105 R-GGA-3299753 https://reactome.org/PathwayBrowser/#/R-GGA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Gallus gallus 29105 R-GGA-3697860 https://reactome.org/PathwayBrowser/#/R-GGA-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Gallus gallus 29105 R-GGA-3777112 https://reactome.org/PathwayBrowser/#/R-GGA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Gallus gallus 29105 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 29105 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 29105 R-GGA-421472 https://reactome.org/PathwayBrowser/#/R-GGA-421472 2 delta-aminolevulinate => porphobilinogen + 2 H2O IEA Gallus gallus 29105 R-GGA-428262 https://reactome.org/PathwayBrowser/#/R-GGA-428262 ACER3 hydrolyzes phytoceramide IEA Gallus gallus 29105 R-GGA-435171 https://reactome.org/PathwayBrowser/#/R-GGA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Gallus gallus 29105 R-GGA-435366 https://reactome.org/PathwayBrowser/#/R-GGA-435366 ZnT1 mediates the efflux of zinc from the cell IEA Gallus gallus 29105 R-GGA-437085 https://reactome.org/PathwayBrowser/#/R-GGA-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Gallus gallus 29105 R-GGA-437136 https://reactome.org/PathwayBrowser/#/R-GGA-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Gallus gallus 29105 R-GGA-437139 https://reactome.org/PathwayBrowser/#/R-GGA-437139 ZnT8 transports zinc into the Golgi apparatus IEA Gallus gallus 29105 R-GGA-442317 https://reactome.org/PathwayBrowser/#/R-GGA-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Gallus gallus 29105 R-GGA-442387 https://reactome.org/PathwayBrowser/#/R-GGA-442387 ZIP8 mediates zinc influx into cells IEA Gallus gallus 29105 R-GGA-442393 https://reactome.org/PathwayBrowser/#/R-GGA-442393 ZIP7 mediates zinc efflux from the endoplasmic reticulum IEA Gallus gallus 29105 R-GGA-442422 https://reactome.org/PathwayBrowser/#/R-GGA-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Gallus gallus 29105 R-GGA-444572 https://reactome.org/PathwayBrowser/#/R-GGA-444572 Zinc is an agonist of GPR39 IEA Gallus gallus 29105 R-GGA-4551451 https://reactome.org/PathwayBrowser/#/R-GGA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Gallus gallus 29105 R-GGA-4551465 https://reactome.org/PathwayBrowser/#/R-GGA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Gallus gallus 29105 R-GGA-4837364 https://reactome.org/PathwayBrowser/#/R-GGA-4837364 Secretion of SOD3 IEA Gallus gallus 29105 R-GGA-5362564 https://reactome.org/PathwayBrowser/#/R-GGA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Gallus gallus 29105 R-GGA-5433067 https://reactome.org/PathwayBrowser/#/R-GGA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Gallus gallus 29105 R-GGA-5433074 https://reactome.org/PathwayBrowser/#/R-GGA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Gallus gallus 29105 R-GGA-5652195 https://reactome.org/PathwayBrowser/#/R-GGA-5652195 SORD oxidizes D-sorbitol to Fru IEA Gallus gallus 29105 R-GGA-5661217 https://reactome.org/PathwayBrowser/#/R-GGA-5661217 MT1A binds zinc IEA Gallus gallus 29105 R-GGA-5662471 https://reactome.org/PathwayBrowser/#/R-GGA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Gallus gallus 29105 R-GGA-5662606 https://reactome.org/PathwayBrowser/#/R-GGA-5662606 MT3 binds zinc IEA Gallus gallus 29105 R-GGA-5662613 https://reactome.org/PathwayBrowser/#/R-GGA-5662613 MT3 exchanges zinc for copper IEA Gallus gallus 29105 R-GGA-5662660 https://reactome.org/PathwayBrowser/#/R-GGA-5662660 Dopachrome is transformed to DHICA by DCT IEA Gallus gallus 29105 R-GGA-5682586 https://reactome.org/PathwayBrowser/#/R-GGA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Gallus gallus 29105 R-GGA-5682588 https://reactome.org/PathwayBrowser/#/R-GGA-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Gallus gallus 29105 R-GGA-5682598 https://reactome.org/PathwayBrowser/#/R-GGA-5682598 ATM phosphorylates HERC2 IEA Gallus gallus 29105 R-GGA-5682607 https://reactome.org/PathwayBrowser/#/R-GGA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Gallus gallus 29105 R-GGA-5682629 https://reactome.org/PathwayBrowser/#/R-GGA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Gallus gallus 29105 R-GGA-5682858 https://reactome.org/PathwayBrowser/#/R-GGA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Gallus gallus 29105 R-GGA-5682863 https://reactome.org/PathwayBrowser/#/R-GGA-5682863 RNF168 binds DNA DSBs IEA Gallus gallus 29105 R-GGA-5683077 https://reactome.org/PathwayBrowser/#/R-GGA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Gallus gallus 29105 R-GGA-5683384 https://reactome.org/PathwayBrowser/#/R-GGA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Gallus gallus 29105 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus 29105 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus 29105 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus 29105 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus 29105 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus 29105 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus 29105 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus 29105 R-GGA-5686900 https://reactome.org/PathwayBrowser/#/R-GGA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Gallus gallus 29105 R-GGA-5688276 https://reactome.org/PathwayBrowser/#/R-GGA-5688276 SIRT4 transfers ADPRib to GLUD IEA Gallus gallus 29105 R-GGA-5688289 https://reactome.org/PathwayBrowser/#/R-GGA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Gallus gallus 29105 R-GGA-5688294 https://reactome.org/PathwayBrowser/#/R-GGA-5688294 SIRT5 deacetylates Cytochrome C IEA Gallus gallus 29105 R-GGA-5691507 https://reactome.org/PathwayBrowser/#/R-GGA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Gallus gallus 29105 R-GGA-5692237 https://reactome.org/PathwayBrowser/#/R-GGA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Gallus gallus 29105 R-GGA-5693346 https://reactome.org/PathwayBrowser/#/R-GGA-5693346 CECRI deaminates Ade-Rib to Ino IEA Gallus gallus 29105 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus 29105 R-GGA-5693566 https://reactome.org/PathwayBrowser/#/R-GGA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Gallus gallus 29105 R-GGA-5694071 https://reactome.org/PathwayBrowser/#/R-GGA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Gallus gallus 29105 R-GGA-5694082 https://reactome.org/PathwayBrowser/#/R-GGA-5694082 XK:KEL:Zn2+ cleaves EDN3 IEA Gallus gallus 29105 R-GGA-5696838 https://reactome.org/PathwayBrowser/#/R-GGA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Gallus gallus 29105 R-GGA-6783221 https://reactome.org/PathwayBrowser/#/R-GGA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Gallus gallus 29105 R-GGA-6788650 https://reactome.org/PathwayBrowser/#/R-GGA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Gallus gallus 29105 R-GGA-6798474 https://reactome.org/PathwayBrowser/#/R-GGA-6798474 S100A8:S100A9 binds Zn2+ IEA Gallus gallus 29105 R-GGA-6798489 https://reactome.org/PathwayBrowser/#/R-GGA-6798489 S100A7 or S100A7A binds Zn2+ IEA Gallus gallus 29105 R-GGA-6799545 https://reactome.org/PathwayBrowser/#/R-GGA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Gallus gallus 29105 R-GGA-6799581 https://reactome.org/PathwayBrowser/#/R-GGA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Gallus gallus 29105 R-GGA-6799977 https://reactome.org/PathwayBrowser/#/R-GGA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Gallus gallus 29105 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus 29105 R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus 29105 R-GGA-73589 https://reactome.org/PathwayBrowser/#/R-GGA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Gallus gallus 29105 R-GGA-73591 https://reactome.org/PathwayBrowser/#/R-GGA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Gallus gallus 29105 R-GGA-73608 https://reactome.org/PathwayBrowser/#/R-GGA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Gallus gallus 29105 R-GGA-73618 https://reactome.org/PathwayBrowser/#/R-GGA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Gallus gallus 29105 R-GGA-73620 https://reactome.org/PathwayBrowser/#/R-GGA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Gallus gallus 29105 R-GGA-74255 https://reactome.org/PathwayBrowser/#/R-GGA-74255 Guanine + H2O => Xanthine + NH4+ IEA Gallus gallus 29105 R-GGA-74730 https://reactome.org/PathwayBrowser/#/R-GGA-74730 Insulin degradation IEA Gallus gallus 29105 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 29105 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 29105 R-GGA-880007 https://reactome.org/PathwayBrowser/#/R-GGA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus 29105 R-GGA-8866601 https://reactome.org/PathwayBrowser/#/R-GGA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Gallus gallus 29105 R-GGA-8867344 https://reactome.org/PathwayBrowser/#/R-GGA-8867344 OMA1 hydrolyses OPA1 IEA Gallus gallus 29105 R-GGA-8878787 https://reactome.org/PathwayBrowser/#/R-GGA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Gallus gallus 29105 R-GGA-8940070 https://reactome.org/PathwayBrowser/#/R-GGA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Gallus gallus 29105 R-GGA-8940074 https://reactome.org/PathwayBrowser/#/R-GGA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Gallus gallus 29105 R-GGA-8949649 https://reactome.org/PathwayBrowser/#/R-GGA-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) IEA Gallus gallus 29105 R-GGA-8949659 https://reactome.org/PathwayBrowser/#/R-GGA-8949659 AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU IEA Gallus gallus 29105 R-GGA-8949661 https://reactome.org/PathwayBrowser/#/R-GGA-8949661 C2orf47:AFG3L2 binds the transit peptide of SMDT1 IEA Gallus gallus 29105 R-GGA-8949668 https://reactome.org/PathwayBrowser/#/R-GGA-8949668 YME1L1 proteolyzes unassembled proSMDT1 IEA Gallus gallus 29105 R-GGA-8951723 https://reactome.org/PathwayBrowser/#/R-GGA-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Gallus gallus 29105 R-GGA-9013284 https://reactome.org/PathwayBrowser/#/R-GGA-9013284 NOTCH3-ligand complex is cleaved to produce NEXT3 IEA Gallus gallus 29105 R-GGA-9018862 https://reactome.org/PathwayBrowser/#/R-GGA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Gallus gallus 29105 R-GGA-9018877 https://reactome.org/PathwayBrowser/#/R-GGA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Gallus gallus 29105 R-GGA-9020252 https://reactome.org/PathwayBrowser/#/R-GGA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Gallus gallus 29105 R-GGA-9020253 https://reactome.org/PathwayBrowser/#/R-GGA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Gallus gallus 29105 R-GGA-9020257 https://reactome.org/PathwayBrowser/#/R-GGA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Gallus gallus 29105 R-GGA-9020258 https://reactome.org/PathwayBrowser/#/R-GGA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Gallus gallus 29105 R-GGA-9020270 https://reactome.org/PathwayBrowser/#/R-GGA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Gallus gallus 29105 R-GGA-9024890 https://reactome.org/PathwayBrowser/#/R-GGA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Gallus gallus 29105 R-GGA-947514 https://reactome.org/PathwayBrowser/#/R-GGA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Gallus gallus 29105 R-GGA-9610152 https://reactome.org/PathwayBrowser/#/R-GGA-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Gallus gallus 29105 R-GGA-9610153 https://reactome.org/PathwayBrowser/#/R-GGA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Gallus gallus 29105 R-GGA-9610154 https://reactome.org/PathwayBrowser/#/R-GGA-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Gallus gallus 29105 R-GGA-9610156 https://reactome.org/PathwayBrowser/#/R-GGA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Gallus gallus 29105 R-GGA-9610163 https://reactome.org/PathwayBrowser/#/R-GGA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Gallus gallus 29105 R-GGA-9647977 https://reactome.org/PathwayBrowser/#/R-GGA-9647977 ICMT methylates S-Farn RAS proteins IEA Gallus gallus 29105 R-GGA-964958 https://reactome.org/PathwayBrowser/#/R-GGA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Gallus gallus 29105 R-GGA-964962 https://reactome.org/PathwayBrowser/#/R-GGA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Gallus gallus 29105 R-GGA-964970 https://reactome.org/PathwayBrowser/#/R-GGA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Gallus gallus 29105 R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 29105 R-GGA-9727607 https://reactome.org/PathwayBrowser/#/R-GGA-9727607 MME:Zn2+ binds sacubitrilat IEA Gallus gallus 29105 R-GGA-9731661 https://reactome.org/PathwayBrowser/#/R-GGA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Gallus gallus 29105 R-GGA-9753944 https://reactome.org/PathwayBrowser/#/R-GGA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Gallus gallus 29105 R-GGA-975814 https://reactome.org/PathwayBrowser/#/R-GGA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Gallus gallus 29105 R-GGA-976991 https://reactome.org/PathwayBrowser/#/R-GGA-976991 Prolactin receptor ligands bind the prolactin receptor IEA Gallus gallus 29105 R-GGA-9820566 https://reactome.org/PathwayBrowser/#/R-GGA-9820566 ZnT5 transports zinc into the golgi apparatus IEA Gallus gallus 29105 R-GGA-982810 https://reactome.org/PathwayBrowser/#/R-GGA-982810 JAK2 phosphorylation IEA Gallus gallus 29105 R-GGA-9838627 https://reactome.org/PathwayBrowser/#/R-GGA-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Gallus gallus 29105 R-GGA-9839053 https://reactome.org/PathwayBrowser/#/R-GGA-9839053 AFG3L2:SPG7 binds SMDT1 (EMRE) IEA Gallus gallus 29105 R-GGA-9839059 https://reactome.org/PathwayBrowser/#/R-GGA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Gallus gallus 29105 R-GGA-9839105 https://reactome.org/PathwayBrowser/#/R-GGA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Gallus gallus 29105 R-GGA-9839113 https://reactome.org/PathwayBrowser/#/R-GGA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Gallus gallus 29105 R-GGA-9839149 https://reactome.org/PathwayBrowser/#/R-GGA-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Gallus gallus 29105 R-GGA-9840564 https://reactome.org/PathwayBrowser/#/R-GGA-9840564 OMA1 hydrolyzes YME1L1 IEA Gallus gallus 29105 R-GGA-9854463 https://reactome.org/PathwayBrowser/#/R-GGA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Gallus gallus 29105 R-GGA-9861626 https://reactome.org/PathwayBrowser/#/R-GGA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Gallus gallus 29105 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 29105 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 29105 R-HSA-1170539 https://reactome.org/PathwayBrowser/#/R-HSA-1170539 Prolactin receptor is internalized TAS Homo sapiens 29105 R-HSA-1222583 https://reactome.org/PathwayBrowser/#/R-HSA-1222583 MscR reduces nitrosomycothiol to ammonia TAS Homo sapiens 29105 R-HSA-1237045 https://reactome.org/PathwayBrowser/#/R-HSA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton TAS Homo sapiens 29105 R-HSA-1237047 https://reactome.org/PathwayBrowser/#/R-HSA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- TAS Homo sapiens 29105 R-HSA-1237059 https://reactome.org/PathwayBrowser/#/R-HSA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 TAS Homo sapiens 29105 R-HSA-1237081 https://reactome.org/PathwayBrowser/#/R-HSA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide TAS Homo sapiens 29105 R-HSA-1237140 https://reactome.org/PathwayBrowser/#/R-HSA-1237140 Dehydration of methylthio-ribulose-P IEA Homo sapiens 29105 R-HSA-1251992 https://reactome.org/PathwayBrowser/#/R-HSA-1251992 Cleavage of P-ERBB4jmA isoforms by ADAM17 IEA Homo sapiens 29105 R-HSA-1299476 https://reactome.org/PathwayBrowser/#/R-HSA-1299476 MPP cleaves targeting peptide (presequence) of inner membrane precursors IEA Homo sapiens 29105 R-HSA-1299478 https://reactome.org/PathwayBrowser/#/R-HSA-1299478 MPP cleaves targeting peptide (presequence) of matrix precursors IEA Homo sapiens 29105 R-HSA-1364043 https://reactome.org/PathwayBrowser/#/R-HSA-1364043 Tyrosine phosphorylation of PRLR IEA Homo sapiens 29105 R-HSA-1369080 https://reactome.org/PathwayBrowser/#/R-HSA-1369080 PRLR binds STAT5 IEA Homo sapiens 29105 R-HSA-1369114 https://reactome.org/PathwayBrowser/#/R-HSA-1369114 PRLR binds SHP2 (PTPN11) IEA Homo sapiens 29105 R-HSA-1369115 https://reactome.org/PathwayBrowser/#/R-HSA-1369115 SHP2 is phosphorylated IEA Homo sapiens 29105 R-HSA-1370500 https://reactome.org/PathwayBrowser/#/R-HSA-1370500 PRLR binds SCF beta-TrCP complex TAS Homo sapiens 29105 R-HSA-1370505 https://reactome.org/PathwayBrowser/#/R-HSA-1370505 PRLR is phosphorylated at Ser-349 TAS Homo sapiens 29105 R-HSA-1474184 https://reactome.org/PathwayBrowser/#/R-HSA-1474184 DHNTP is dephosphorylated by PTPS to PTHP TAS Homo sapiens 29105 R-HSA-1475017 https://reactome.org/PathwayBrowser/#/R-HSA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) TAS Homo sapiens 29105 R-HSA-1475022 https://reactome.org/PathwayBrowser/#/R-HSA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) TAS Homo sapiens 29105 R-HSA-1475025 https://reactome.org/PathwayBrowser/#/R-HSA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) TAS Homo sapiens 29105 R-HSA-1475026 https://reactome.org/PathwayBrowser/#/R-HSA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) TAS Homo sapiens 29105 R-HSA-1475028 https://reactome.org/PathwayBrowser/#/R-HSA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) TAS Homo sapiens 29105 R-HSA-1475032 https://reactome.org/PathwayBrowser/#/R-HSA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) TAS Homo sapiens 29105 R-HSA-1475422 https://reactome.org/PathwayBrowser/#/R-HSA-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II TAS Homo sapiens 29105 R-HSA-1475435 https://reactome.org/PathwayBrowser/#/R-HSA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- TAS Homo sapiens 29105 R-HSA-1475436 https://reactome.org/PathwayBrowser/#/R-HSA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 TAS Homo sapiens 29105 R-HSA-1497784 https://reactome.org/PathwayBrowser/#/R-HSA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle TAS Homo sapiens 29105 R-HSA-1497796 https://reactome.org/PathwayBrowser/#/R-HSA-1497796 BH2 binding can lead to eNOS uncoupling TAS Homo sapiens 29105 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 29105 R-HSA-157629 https://reactome.org/PathwayBrowser/#/R-HSA-157629 NOTCH2-ligand complex is cleaved to produce NEXT2 IEA Homo sapiens 29105 R-HSA-157632 https://reactome.org/PathwayBrowser/#/R-HSA-157632 Complex of NOTCH1 with its ligand is cleaved to produce NEXT1 IEA Homo sapiens 29105 R-HSA-158354 https://reactome.org/PathwayBrowser/#/R-HSA-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer TAS Homo sapiens 29105 R-HSA-158941 https://reactome.org/PathwayBrowser/#/R-HSA-158941 plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein TAS Homo sapiens 29105 R-HSA-1614605 https://reactome.org/PathwayBrowser/#/R-HSA-1614605 Persulfide sulfur is dioxygenated TAS Homo sapiens 29105 R-HSA-1614654 https://reactome.org/PathwayBrowser/#/R-HSA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY TAS Homo sapiens 29105 R-HSA-1655826 https://reactome.org/PathwayBrowser/#/R-HSA-1655826 Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) TAS Homo sapiens 29105 R-HSA-1671687 https://reactome.org/PathwayBrowser/#/R-HSA-1671687 PRLR activation TAS Homo sapiens 29105 R-HSA-1671691 https://reactome.org/PathwayBrowser/#/R-HSA-1671691 PRLR-bound STAT5 is phosphorylated IEA Homo sapiens 29105 R-HSA-1675473 https://reactome.org/PathwayBrowser/#/R-HSA-1675473 SH2B binds JAK2 TAS Homo sapiens 29105 R-HSA-169901 https://reactome.org/PathwayBrowser/#/R-HSA-169901 Rap1-GTP complex binds BRAF complex IEA Homo sapiens 29105 R-HSA-170965 https://reactome.org/PathwayBrowser/#/R-HSA-170965 (Frs2)Rap1-GTP binds to and activates B-Raf IEA Homo sapiens 29105 R-HSA-174374 https://reactome.org/PathwayBrowser/#/R-HSA-174374 MTR transfers CH3 from MeCbl to HCYS TAS Homo sapiens 29105 R-HSA-177946 https://reactome.org/PathwayBrowser/#/R-HSA-177946 Pro-EGF is cleaved to form mature EGF IEA Homo sapiens 29105 R-HSA-181567 https://reactome.org/PathwayBrowser/#/R-HSA-181567 botC LC cleaves target cell STX1 TAS Homo sapiens 29105 R-HSA-187698 https://reactome.org/PathwayBrowser/#/R-HSA-187698 RIT/RIN-GTP binds B-RAF IEA Homo sapiens 29105 R-HSA-189384 https://reactome.org/PathwayBrowser/#/R-HSA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL TAS Homo sapiens 29105 R-HSA-189439 https://reactome.org/PathwayBrowser/#/R-HSA-189439 ALAD condenses 2 dALAs to form PBG TAS Homo sapiens 29105 R-HSA-190141 https://reactome.org/PathwayBrowser/#/R-HSA-190141 ALAD binds to Pb2+ TAS Homo sapiens 29105 R-HSA-193679 https://reactome.org/PathwayBrowser/#/R-HSA-193679 alpha-secretase cleaves the p75NTR extracellular domain TAS Homo sapiens 29105 R-HSA-194793 https://reactome.org/PathwayBrowser/#/R-HSA-194793 botC LC cleaves target cell SNAP25 TAS Homo sapiens 29105 R-HSA-194796 https://reactome.org/PathwayBrowser/#/R-HSA-194796 botB LC cleaves target cell VAMP2 TAS Homo sapiens 29105 R-HSA-194800 https://reactome.org/PathwayBrowser/#/R-HSA-194800 botE LC cleaves target cell SNAP25 TAS Homo sapiens 29105 R-HSA-194808 https://reactome.org/PathwayBrowser/#/R-HSA-194808 botF LC cleaves target cell VAMP1 TAS Homo sapiens 29105 R-HSA-194809 https://reactome.org/PathwayBrowser/#/R-HSA-194809 botD LC cleaves target cell VAMP1 TAS Homo sapiens 29105 R-HSA-194818 https://reactome.org/PathwayBrowser/#/R-HSA-194818 botA LC cleaves target cell SNAP25 TAS Homo sapiens 29105 R-HSA-197198 https://reactome.org/PathwayBrowser/#/R-HSA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ TAS Homo sapiens 29105 R-HSA-200512 https://reactome.org/PathwayBrowser/#/R-HSA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 29105 R-HSA-201783 https://reactome.org/PathwayBrowser/#/R-HSA-201783 Inactive catalytic PP2B is activated by the binding of calmodulin IEA Homo sapiens 29105 R-HSA-201787 https://reactome.org/PathwayBrowser/#/R-HSA-201787 PPP3 complex dephosphorylates DARPP-32 on Thr34 IEA Homo sapiens 29105 R-HSA-202110 https://reactome.org/PathwayBrowser/#/R-HSA-202110 eNOS:Caveolin-1 complex binds to CaM TAS Homo sapiens 29105 R-HSA-202111 https://reactome.org/PathwayBrowser/#/R-HSA-202111 AKT1 phosphorylates eNOS TAS Homo sapiens 29105 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 29105 R-HSA-202129 https://reactome.org/PathwayBrowser/#/R-HSA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex TAS Homo sapiens 29105 R-HSA-202132 https://reactome.org/PathwayBrowser/#/R-HSA-202132 depalmitoylated eNOS translocates from plasma membrane TAS Homo sapiens 29105 R-HSA-202137 https://reactome.org/PathwayBrowser/#/R-HSA-202137 AKT1 binds eNOS complex via HSP90 TAS Homo sapiens 29105 R-HSA-202144 https://reactome.org/PathwayBrowser/#/R-HSA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex TAS Homo sapiens 29105 R-HSA-2022368 https://reactome.org/PathwayBrowser/#/R-HSA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) TAS Homo sapiens 29105 R-HSA-2022378 https://reactome.org/PathwayBrowser/#/R-HSA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) TAS Homo sapiens 29105 R-HSA-2022379 https://reactome.org/PathwayBrowser/#/R-HSA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) TAS Homo sapiens 29105 R-HSA-2022393 https://reactome.org/PathwayBrowser/#/R-HSA-2022393 ANPEP:Zn2+ hydrolyzes Angiotensin-(2-8) to Angiotensin-(3-8) IEA Homo sapiens 29105 R-HSA-2022396 https://reactome.org/PathwayBrowser/#/R-HSA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) TAS Homo sapiens 29105 R-HSA-2022398 https://reactome.org/PathwayBrowser/#/R-HSA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) TAS Homo sapiens 29105 R-HSA-2022399 https://reactome.org/PathwayBrowser/#/R-HSA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) TAS Homo sapiens 29105 R-HSA-2022405 https://reactome.org/PathwayBrowser/#/R-HSA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 29105 R-HSA-2025882 https://reactome.org/PathwayBrowser/#/R-HSA-2025882 Calcineurin dephosphorylates NFATC1,2,3 IEA Homo sapiens 29105 R-HSA-2025890 https://reactome.org/PathwayBrowser/#/R-HSA-2025890 Calcineurin binds NFATC1,2,3 TAS Homo sapiens 29105 R-HSA-2028294 https://reactome.org/PathwayBrowser/#/R-HSA-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) TAS Homo sapiens 29105 R-HSA-203553 https://reactome.org/PathwayBrowser/#/R-HSA-203553 eNOS binds NOSIP TAS Homo sapiens 29105 R-HSA-203565 https://reactome.org/PathwayBrowser/#/R-HSA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP TAS Homo sapiens 29105 R-HSA-203613 https://reactome.org/PathwayBrowser/#/R-HSA-203613 depalmitoylation of eNOS TAS Homo sapiens 29105 R-HSA-203625 https://reactome.org/PathwayBrowser/#/R-HSA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane TAS Homo sapiens 29105 R-HSA-203662 https://reactome.org/PathwayBrowser/#/R-HSA-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 TAS Homo sapiens 29105 R-HSA-203680 https://reactome.org/PathwayBrowser/#/R-HSA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments TAS Homo sapiens 29105 R-HSA-203700 https://reactome.org/PathwayBrowser/#/R-HSA-203700 eNOS translocation from Golgi to Caveolae TAS Homo sapiens 29105 R-HSA-203712 https://reactome.org/PathwayBrowser/#/R-HSA-203712 eNOS associates with Caveolin-1 TAS Homo sapiens 29105 R-HSA-203716 https://reactome.org/PathwayBrowser/#/R-HSA-203716 eNOS:Caveolin-1 complex binds to Nostrin TAS Homo sapiens 29105 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 29105 R-HSA-2161187 https://reactome.org/PathwayBrowser/#/R-HSA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine TAS Homo sapiens 29105 R-HSA-2161195 https://reactome.org/PathwayBrowser/#/R-HSA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine TAS Homo sapiens 29105 R-HSA-2162078 https://reactome.org/PathwayBrowser/#/R-HSA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ TAS Homo sapiens 29105 R-HSA-2220944 https://reactome.org/PathwayBrowser/#/R-HSA-2220944 ADAM10/17 cleaves ligand-bound NOTCH1 PEST domain mutants to produce NEXT1 PEST domain mutants TAS Homo sapiens 29105 R-HSA-2220976 https://reactome.org/PathwayBrowser/#/R-HSA-2220976 NOTCH1 HD+PEST domain mutants are cleaved by ADAM10/17 irrespective of ligand binding TAS Homo sapiens 29105 R-HSA-264758 https://reactome.org/PathwayBrowser/#/R-HSA-264758 BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 TAS Homo sapiens 29105 R-HSA-264976 https://reactome.org/PathwayBrowser/#/R-HSA-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium TAS Homo sapiens 29105 R-HSA-265153 https://reactome.org/PathwayBrowser/#/R-HSA-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule TAS Homo sapiens 29105 R-HSA-265160 https://reactome.org/PathwayBrowser/#/R-HSA-265160 Insulin secretory granule translocates to cell cortex IEA Homo sapiens 29105 R-HSA-265166 https://reactome.org/PathwayBrowser/#/R-HSA-265166 Exocytosis of Insulin IEA Homo sapiens 29105 R-HSA-265682 https://reactome.org/PathwayBrowser/#/R-HSA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel TAS Homo sapiens 29105 R-HSA-266012 https://reactome.org/PathwayBrowser/#/R-HSA-266012 LTD4 is converted to LTE4 by DPEP1/2 TAS Homo sapiens 29105 R-HSA-266072 https://reactome.org/PathwayBrowser/#/R-HSA-266072 LTA4 is hydolysed to LTB4 by LTA4H TAS Homo sapiens 29105 R-HSA-2666278 https://reactome.org/PathwayBrowser/#/R-HSA-2666278 NOTCH1 t(7;9)(NOTCH1:M1580_K2555) is cleaved to produce NEXT1 TAS Homo sapiens 29105 R-HSA-2730752 https://reactome.org/PathwayBrowser/#/R-HSA-2730752 NOTCH1 HD domain mutants are cleaved to produce NEXT1 irrespective of ligand binding TAS Homo sapiens 29105 R-HSA-2730849 https://reactome.org/PathwayBrowser/#/R-HSA-2730849 Calcineurin binds and dephosphorylates NFAT TAS Homo sapiens 29105 R-HSA-2730867 https://reactome.org/PathwayBrowser/#/R-HSA-2730867 Translocation of CaN:CaM:NFAT to nucleus TAS Homo sapiens 29105 R-HSA-2730872 https://reactome.org/PathwayBrowser/#/R-HSA-2730872 Activation of Calcineurin TAS Homo sapiens 29105 R-HSA-3149518 https://reactome.org/PathwayBrowser/#/R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl TAS Homo sapiens 29105 R-HSA-3149539 https://reactome.org/PathwayBrowser/#/R-HSA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin TAS Homo sapiens 29105 R-HSA-3204318 https://reactome.org/PathwayBrowser/#/R-HSA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR TAS Homo sapiens 29105 R-HSA-3299682 https://reactome.org/PathwayBrowser/#/R-HSA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) TAS Homo sapiens 29105 R-HSA-3299691 https://reactome.org/PathwayBrowser/#/R-HSA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) TAS Homo sapiens 29105 R-HSA-3299753 https://reactome.org/PathwayBrowser/#/R-HSA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 TAS Homo sapiens 29105 R-HSA-3318563 https://reactome.org/PathwayBrowser/#/R-HSA-3318563 Defective MTRR does not convert cob(II)alamin to MeCbl TAS Homo sapiens 29105 R-HSA-3321918 https://reactome.org/PathwayBrowser/#/R-HSA-3321918 Defective MTR does not transfer CH3 group from MTHF to cob(I)alamin TAS Homo sapiens 29105 R-HSA-3322140 https://reactome.org/PathwayBrowser/#/R-HSA-3322140 Defective MTR does not transfer CH3 group from MeCbl to HCYS TAS Homo sapiens 29105 R-HSA-3371385 https://reactome.org/PathwayBrowser/#/R-HSA-3371385 TNF-α is cleaved by ADAM17 (TACE) TAS Homo sapiens 29105 R-HSA-3697838 https://reactome.org/PathwayBrowser/#/R-HSA-3697838 ATP7A transfers Cu from ATOX1 to SOD3 IEA Homo sapiens 29105 R-HSA-3697860 https://reactome.org/PathwayBrowser/#/R-HSA-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ TAS Homo sapiens 29105 R-HSA-3777112 https://reactome.org/PathwayBrowser/#/R-HSA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) TAS Homo sapiens 29105 R-HSA-3780958 https://reactome.org/PathwayBrowser/#/R-HSA-3780958 SOD1:Zn2+ apoenzyme binds CCS:Cu1+ (mitochondrial) IEA Homo sapiens 29105 R-HSA-3780979 https://reactome.org/PathwayBrowser/#/R-HSA-3780979 CCS transfers Cu to SOD1 (mitochondrial) IEA Homo sapiens 29105 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 29105 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 29105 R-HSA-428262 https://reactome.org/PathwayBrowser/#/R-HSA-428262 ACER3 hydrolyzes phytoceramide TAS Homo sapiens 29105 R-HSA-435171 https://reactome.org/PathwayBrowser/#/R-HSA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages TAS Homo sapiens 29105 R-HSA-435366 https://reactome.org/PathwayBrowser/#/R-HSA-435366 ZnT1 mediates the efflux of zinc from the cell TAS Homo sapiens 29105 R-HSA-435375 https://reactome.org/PathwayBrowser/#/R-HSA-435375 ZnT2 facilitates zinc vesicular sequestration IEA Homo sapiens 29105 R-HSA-437084 https://reactome.org/PathwayBrowser/#/R-HSA-437084 ZnT3 transports zinc into synaptic vesicles IEA Homo sapiens 29105 R-HSA-437085 https://reactome.org/PathwayBrowser/#/R-HSA-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells TAS Homo sapiens 29105 R-HSA-437136 https://reactome.org/PathwayBrowser/#/R-HSA-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule TAS Homo sapiens 29105 R-HSA-437139 https://reactome.org/PathwayBrowser/#/R-HSA-437139 ZnT8 transports zinc into the Golgi apparatus TAS Homo sapiens 29105 R-HSA-442317 https://reactome.org/PathwayBrowser/#/R-HSA-442317 ZIP6 and ZIP14 mediate zinc influx into cells TAS Homo sapiens 29105 R-HSA-442345 https://reactome.org/PathwayBrowser/#/R-HSA-442345 hZIP10 mediates zinc influx into cells IEA Homo sapiens 29105 R-HSA-442387 https://reactome.org/PathwayBrowser/#/R-HSA-442387 ZIP8 mediates zinc influx into cells TAS Homo sapiens 29105 R-HSA-442393 https://reactome.org/PathwayBrowser/#/R-HSA-442393 ZIP7 mediates zinc efflux from the endoplasmic reticulum TAS Homo sapiens 29105 R-HSA-442405 https://reactome.org/PathwayBrowser/#/R-HSA-442405 hZIP5 mediates zinc uptake by cells IEA Homo sapiens 29105 R-HSA-442422 https://reactome.org/PathwayBrowser/#/R-HSA-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol TAS Homo sapiens 29105 R-HSA-444572 https://reactome.org/PathwayBrowser/#/R-HSA-444572 Zinc is an agonist of GPR39 TAS Homo sapiens 29105 R-HSA-4551451 https://reactome.org/PathwayBrowser/#/R-HSA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling TAS Homo sapiens 29105 R-HSA-4551465 https://reactome.org/PathwayBrowser/#/R-HSA-4551465 Translocation of NFATC1:CaN:CaM to nucleus TAS Homo sapiens 29105 R-HSA-4837364 https://reactome.org/PathwayBrowser/#/R-HSA-4837364 Secretion of SOD3 TAS Homo sapiens 29105 R-HSA-5210892 https://reactome.org/PathwayBrowser/#/R-HSA-5210892 cya and lef bind to pagA(197-794):ANTXR2 oligomer TAS Homo sapiens 29105 R-HSA-5210923 https://reactome.org/PathwayBrowser/#/R-HSA-5210923 cya and lef bind to pagA(197-794):ANTXR1 oligomer TAS Homo sapiens 29105 R-HSA-5210943 https://reactome.org/PathwayBrowser/#/R-HSA-5210943 pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol) TAS Homo sapiens 29105 R-HSA-5210944 https://reactome.org/PathwayBrowser/#/R-HSA-5210944 Endocytosis of cya:lef:(pagA(197-794):ANTXR1 oligomer) (plasma membrane to endosome membrane) TAS Homo sapiens 29105 R-HSA-5210947 https://reactome.org/PathwayBrowser/#/R-HSA-5210947 pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol) TAS Homo sapiens 29105 R-HSA-5210959 https://reactome.org/PathwayBrowser/#/R-HSA-5210959 Endocytosis of cya:lef:(pagA(197-794):ANTXR2 oligomer) (plasma membrane to endosome membrane) TAS Homo sapiens 29105 R-HSA-5211340 https://reactome.org/PathwayBrowser/#/R-HSA-5211340 Anthrax lef cleaves target cell MAP2K1 (MEK1) TAS Homo sapiens 29105 R-HSA-5211356 https://reactome.org/PathwayBrowser/#/R-HSA-5211356 Anthrax lef cleaves target cell MAP2K2 (MEK2) TAS Homo sapiens 29105 R-HSA-5211387 https://reactome.org/PathwayBrowser/#/R-HSA-5211387 Anthrax lef cleaves target cell MAP2K7 (MEK7) TAS Homo sapiens 29105 R-HSA-5211391 https://reactome.org/PathwayBrowser/#/R-HSA-5211391 Anthrax lef cleaves target cell MAP2K4 (MEK4) TAS Homo sapiens 29105 R-HSA-5211400 https://reactome.org/PathwayBrowser/#/R-HSA-5211400 Anthrax lef cleaves target cell MAP2K3 (MEK3) TAS Homo sapiens 29105 R-HSA-5211405 https://reactome.org/PathwayBrowser/#/R-HSA-5211405 Anthrax lef cleaves target cell MAP2K6 (MEK6) TAS Homo sapiens 29105 R-HSA-5228406 https://reactome.org/PathwayBrowser/#/R-HSA-5228406 tetX HC transports tetX LC from target cell endosome membrane into cytosol TAS Homo sapiens 29105 R-HSA-5228407 https://reactome.org/PathwayBrowser/#/R-HSA-5228407 tetX HC:LC binds target cell-surface gangliosides TAS Homo sapiens 29105 R-HSA-5228408 https://reactome.org/PathwayBrowser/#/R-HSA-5228408 Retrograde transport of internalized tetX HC:LC:gangliosides TAS Homo sapiens 29105 R-HSA-5228411 https://reactome.org/PathwayBrowser/#/R-HSA-5228411 Clathrin-mediated endocytosis of tetX HC:LC:gangliosides TAS Homo sapiens 29105 R-HSA-5228578 https://reactome.org/PathwayBrowser/#/R-HSA-5228578 tetX LC cleaves target cell VAMP2 TAS Homo sapiens 29105 R-HSA-5228940 https://reactome.org/PathwayBrowser/#/R-HSA-5228940 Transcytosis and dissociation of botB:NTNHA:HA TAS Homo sapiens 29105 R-HSA-5228941 https://reactome.org/PathwayBrowser/#/R-HSA-5228941 Transcytosis and dissociation of botE:NTNHA TAS Homo sapiens 29105 R-HSA-5228943 https://reactome.org/PathwayBrowser/#/R-HSA-5228943 Transcytosis and dissociation of botA:NTNHA:HA TAS Homo sapiens 29105 R-HSA-5244397 https://reactome.org/PathwayBrowser/#/R-HSA-5244397 botB HC:LC binds SYT1 or 2 and GT1b on the target cell surface TAS Homo sapiens 29105 R-HSA-5244402 https://reactome.org/PathwayBrowser/#/R-HSA-5244402 botB:SYT:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 29105 R-HSA-5244404 https://reactome.org/PathwayBrowser/#/R-HSA-5244404 botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 29105 R-HSA-5244415 https://reactome.org/PathwayBrowser/#/R-HSA-5244415 botA HC:LC binds SV2A, B, or C and GT1b on the target cell surface TAS Homo sapiens 29105 R-HSA-5244424 https://reactome.org/PathwayBrowser/#/R-HSA-5244424 botA:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 29105 R-HSA-5244428 https://reactome.org/PathwayBrowser/#/R-HSA-5244428 botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 29105 R-HSA-5244500 https://reactome.org/PathwayBrowser/#/R-HSA-5244500 botE:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 29105 R-HSA-5244503 https://reactome.org/PathwayBrowser/#/R-HSA-5244503 botE HC:LC binds SV2A or B and GT1b on the target cell surface TAS Homo sapiens 29105 R-HSA-5244506 https://reactome.org/PathwayBrowser/#/R-HSA-5244506 botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 29105 R-HSA-5246506 https://reactome.org/PathwayBrowser/#/R-HSA-5246506 botC HC:LC binds GT1b on the target cell surface TAS Homo sapiens 29105 R-HSA-5246509 https://reactome.org/PathwayBrowser/#/R-HSA-5246509 botC:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 29105 R-HSA-5246514 https://reactome.org/PathwayBrowser/#/R-HSA-5246514 botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol TAS Homo sapiens 29105 R-HSA-5250600 https://reactome.org/PathwayBrowser/#/R-HSA-5250600 botD:SV2:GD2 internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 29105 R-HSA-5250606 https://reactome.org/PathwayBrowser/#/R-HSA-5250606 botD LC cleaves target cell VAMP2 TAS Homo sapiens 29105 R-HSA-5250607 https://reactome.org/PathwayBrowser/#/R-HSA-5250607 botD HC:LC binds SV2A or B or C and GD2 on the target cell surface TAS Homo sapiens 29105 R-HSA-5250616 https://reactome.org/PathwayBrowser/#/R-HSA-5250616 botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 29105 R-HSA-5250875 https://reactome.org/PathwayBrowser/#/R-HSA-5250875 botF:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 29105 R-HSA-5250880 https://reactome.org/PathwayBrowser/#/R-HSA-5250880 botF HC:LC binds SV2A or B or C and GT1b on the target cell surface TAS Homo sapiens 29105 R-HSA-5250884 https://reactome.org/PathwayBrowser/#/R-HSA-5250884 botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 29105 R-HSA-5250892 https://reactome.org/PathwayBrowser/#/R-HSA-5250892 botF LC cleaves target cell VAMP2 TAS Homo sapiens 29105 R-HSA-5250962 https://reactome.org/PathwayBrowser/#/R-HSA-5250962 botG LC cleaves target cell VAMP2 TAS Homo sapiens 29105 R-HSA-5250972 https://reactome.org/PathwayBrowser/#/R-HSA-5250972 botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 29105 R-HSA-5250978 https://reactome.org/PathwayBrowser/#/R-HSA-5250978 botG LC cleaves target cell VAMP1 TAS Homo sapiens 29105 R-HSA-5250979 https://reactome.org/PathwayBrowser/#/R-HSA-5250979 botG:SYT1:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 29105 R-HSA-5250986 https://reactome.org/PathwayBrowser/#/R-HSA-5250986 botG HC:LC binds SYT1 and GT1b on the target cell surface TAS Homo sapiens 29105 R-HSA-5362564 https://reactome.org/PathwayBrowser/#/R-HSA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro TAS Homo sapiens 29105 R-HSA-5433067 https://reactome.org/PathwayBrowser/#/R-HSA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG TAS Homo sapiens 29105 R-HSA-5433074 https://reactome.org/PathwayBrowser/#/R-HSA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 29105 R-HSA-5579081 https://reactome.org/PathwayBrowser/#/R-HSA-5579081 Defective ACY1 does not hydrolyse mercapturic acids TAS Homo sapiens 29105 R-HSA-5652195 https://reactome.org/PathwayBrowser/#/R-HSA-5652195 SORD oxidizes D-sorbitol to Fru TAS Homo sapiens 29105 R-HSA-5654125 https://reactome.org/PathwayBrowser/#/R-HSA-5654125 Defective SLC39A4 does not transport Zn2+ from extracellular region to cytosol TAS Homo sapiens 29105 R-HSA-5657651 https://reactome.org/PathwayBrowser/#/R-HSA-5657651 MGMT binds alkylated DNA containing 6-O-methylguanine TAS Homo sapiens 29105 R-HSA-5660479 https://reactome.org/PathwayBrowser/#/R-HSA-5660479 MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein) TAS Homo sapiens 29105 R-HSA-5660503 https://reactome.org/PathwayBrowser/#/R-HSA-5660503 Expression of CSRP1 IEA Homo sapiens 29105 R-HSA-5660514 https://reactome.org/PathwayBrowser/#/R-HSA-5660514 MTF1 dimer:12Zn2+ binds CSRP1 gene IEA Homo sapiens 29105 R-HSA-5660530 https://reactome.org/PathwayBrowser/#/R-HSA-5660530 Expression of SNCB TAS Homo sapiens 29105 R-HSA-5661217 https://reactome.org/PathwayBrowser/#/R-HSA-5661217 MT1A binds zinc TAS Homo sapiens 29105 R-HSA-5662471 https://reactome.org/PathwayBrowser/#/R-HSA-5662471 SORD tetramer oxidizes xylitol to D-xylulose TAS Homo sapiens 29105 R-HSA-5662598 https://reactome.org/PathwayBrowser/#/R-HSA-5662598 MT2A binds zinc IEA Homo sapiens 29105 R-HSA-5662603 https://reactome.org/PathwayBrowser/#/R-HSA-5662603 MT1B binds zinc IEA Homo sapiens 29105 R-HSA-5662606 https://reactome.org/PathwayBrowser/#/R-HSA-5662606 MT3 binds zinc TAS Homo sapiens 29105 R-HSA-5662613 https://reactome.org/PathwayBrowser/#/R-HSA-5662613 MT3 exchanges zinc for copper TAS Homo sapiens 29105 R-HSA-5662614 https://reactome.org/PathwayBrowser/#/R-HSA-5662614 MT1E binds zinc IEA Homo sapiens 29105 R-HSA-5662615 https://reactome.org/PathwayBrowser/#/R-HSA-5662615 MT1X binds zinc IEA Homo sapiens 29105 R-HSA-5662618 https://reactome.org/PathwayBrowser/#/R-HSA-5662618 MT1G binds zinc IEA Homo sapiens 29105 R-HSA-5662619 https://reactome.org/PathwayBrowser/#/R-HSA-5662619 MT1H binds zinc IEA Homo sapiens 29105 R-HSA-5662621 https://reactome.org/PathwayBrowser/#/R-HSA-5662621 MT1M binds zinc IEA Homo sapiens 29105 R-HSA-5662623 https://reactome.org/PathwayBrowser/#/R-HSA-5662623 MT1F binds zinc IEA Homo sapiens 29105 R-HSA-5662653 https://reactome.org/PathwayBrowser/#/R-HSA-5662653 MT4 binds zinc IEA Homo sapiens 29105 R-HSA-5662660 https://reactome.org/PathwayBrowser/#/R-HSA-5662660 Dopachrome is transformed to DHICA by DCT TAS Homo sapiens 29105 R-HSA-5682586 https://reactome.org/PathwayBrowser/#/R-HSA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs TAS Homo sapiens 29105 R-HSA-5682588 https://reactome.org/PathwayBrowser/#/R-HSA-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs TAS Homo sapiens 29105 R-HSA-5682598 https://reactome.org/PathwayBrowser/#/R-HSA-5682598 ATM phosphorylates HERC2 TAS Homo sapiens 29105 R-HSA-5682607 https://reactome.org/PathwayBrowser/#/R-HSA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs TAS Homo sapiens 29105 R-HSA-5682629 https://reactome.org/PathwayBrowser/#/R-HSA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 TAS Homo sapiens 29105 R-HSA-5682858 https://reactome.org/PathwayBrowser/#/R-HSA-5682858 RNF8 and RNF168 ubiquitinate H2AFX TAS Homo sapiens 29105 R-HSA-5682863 https://reactome.org/PathwayBrowser/#/R-HSA-5682863 RNF168 binds DNA DSBs TAS Homo sapiens 29105 R-HSA-5683077 https://reactome.org/PathwayBrowser/#/R-HSA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B TAS Homo sapiens 29105 R-HSA-5683384 https://reactome.org/PathwayBrowser/#/R-HSA-5683384 UIMC1 and FAM175A bind DNA DSBs TAS Homo sapiens 29105 R-HSA-5683385 https://reactome.org/PathwayBrowser/#/R-HSA-5683385 Formation of BRCA1-A complex at DNA DSBs TAS Homo sapiens 29105 R-HSA-5683405 https://reactome.org/PathwayBrowser/#/R-HSA-5683405 PPP5C dephosphorylates TP53BP1 TAS Homo sapiens 29105 R-HSA-5683425 https://reactome.org/PathwayBrowser/#/R-HSA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs TAS Homo sapiens 29105 R-HSA-5683735 https://reactome.org/PathwayBrowser/#/R-HSA-5683735 CHEK2 is recruited to DNA DSBs TAS Homo sapiens 29105 R-HSA-5683801 https://reactome.org/PathwayBrowser/#/R-HSA-5683801 CHEK2 phosphorylates BRCA1 TAS Homo sapiens 29105 R-HSA-5684052 https://reactome.org/PathwayBrowser/#/R-HSA-5684052 PIAS4 SUMOylates MDC1 TAS Homo sapiens 29105 R-HSA-5684071 https://reactome.org/PathwayBrowser/#/R-HSA-5684071 RNF4 ubiquitinates MDC1 TAS Homo sapiens 29105 R-HSA-5686685 https://reactome.org/PathwayBrowser/#/R-HSA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs TAS Homo sapiens 29105 R-HSA-5686704 https://reactome.org/PathwayBrowser/#/R-HSA-5686704 Activated ATM phosphorylates DCLRE1C TAS Homo sapiens 29105 R-HSA-5686900 https://reactome.org/PathwayBrowser/#/R-HSA-5686900 TP53BP1 recruits DCLRE1C to ATM TAS Homo sapiens 29105 R-HSA-5688276 https://reactome.org/PathwayBrowser/#/R-HSA-5688276 SIRT4 transfers ADPRib to GLUD TAS Homo sapiens 29105 R-HSA-5688289 https://reactome.org/PathwayBrowser/#/R-HSA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 TAS Homo sapiens 29105 R-HSA-5688294 https://reactome.org/PathwayBrowser/#/R-HSA-5688294 SIRT5 deacetylates Cytochrome C TAS Homo sapiens 29105 R-HSA-5691507 https://reactome.org/PathwayBrowser/#/R-HSA-5691507 ASPA deacetylates NAA to acetate and L-aspartate TAS Homo sapiens 29105 R-HSA-5692237 https://reactome.org/PathwayBrowser/#/R-HSA-5692237 ADH5 oxidises S-HMGSH to S-FGSH TAS Homo sapiens 29105 R-HSA-5693346 https://reactome.org/PathwayBrowser/#/R-HSA-5693346 CECRI deaminates Ade-Rib to Ino TAS Homo sapiens 29105 R-HSA-5693551 https://reactome.org/PathwayBrowser/#/R-HSA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM TAS Homo sapiens 29105 R-HSA-5693566 https://reactome.org/PathwayBrowser/#/R-HSA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs TAS Homo sapiens 29105 R-HSA-5693599 https://reactome.org/PathwayBrowser/#/R-HSA-5693599 Association of Ku heterodimer with ends of DNA double-strand break TAS Homo sapiens 29105 R-HSA-5694071 https://reactome.org/PathwayBrowser/#/R-HSA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH TAS Homo sapiens 29105 R-HSA-5694082 https://reactome.org/PathwayBrowser/#/R-HSA-5694082 XK:KEL:Zn2+ cleaves EDN3 TAS Homo sapiens 29105 R-HSA-5696838 https://reactome.org/PathwayBrowser/#/R-HSA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS TAS Homo sapiens 29105 R-HSA-6783221 https://reactome.org/PathwayBrowser/#/R-HSA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT TAS Homo sapiens 29105 R-HSA-6788650 https://reactome.org/PathwayBrowser/#/R-HSA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins TAS Homo sapiens 29105 R-HSA-6789072 https://reactome.org/PathwayBrowser/#/R-HSA-6789072 PGLYRP1 binds bacterial peptidoglycan TAS Homo sapiens 29105 R-HSA-6798474 https://reactome.org/PathwayBrowser/#/R-HSA-6798474 S100A8:S100A9 binds Zn2+ TAS Homo sapiens 29105 R-HSA-6798489 https://reactome.org/PathwayBrowser/#/R-HSA-6798489 S100A7 or S100A7A binds Zn2+ TAS Homo sapiens 29105 R-HSA-6799545 https://reactome.org/PathwayBrowser/#/R-HSA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 TAS Homo sapiens 29105 R-HSA-6799581 https://reactome.org/PathwayBrowser/#/R-HSA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man TAS Homo sapiens 29105 R-HSA-6799959 https://reactome.org/PathwayBrowser/#/R-HSA-6799959 PGLYRP3,4 binds bacterial peptidoglycan TAS Homo sapiens 29105 R-HSA-6799977 https://reactome.org/PathwayBrowser/#/R-HSA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan TAS Homo sapiens 29105 R-HSA-6803104 https://reactome.org/PathwayBrowser/#/R-HSA-6803104 DCD forms oligomeric complex TAS Homo sapiens 29105 R-HSA-69891 https://reactome.org/PathwayBrowser/#/R-HSA-69891 Phosphorylation and activation of CHEK2 by ATM TAS Homo sapiens 29105 R-HSA-71707 https://reactome.org/PathwayBrowser/#/R-HSA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ TAS Homo sapiens 29105 R-HSA-73589 https://reactome.org/PathwayBrowser/#/R-HSA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate TAS Homo sapiens 29105 R-HSA-73591 https://reactome.org/PathwayBrowser/#/R-HSA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 TAS Homo sapiens 29105 R-HSA-73608 https://reactome.org/PathwayBrowser/#/R-HSA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) TAS Homo sapiens 29105 R-HSA-73618 https://reactome.org/PathwayBrowser/#/R-HSA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate TAS Homo sapiens 29105 R-HSA-73620 https://reactome.org/PathwayBrowser/#/R-HSA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 TAS Homo sapiens 29105 R-HSA-73892 https://reactome.org/PathwayBrowser/#/R-HSA-73892 MGMT/hAGT mediated DNA Damage Reversal TAS Homo sapiens 29105 R-HSA-74255 https://reactome.org/PathwayBrowser/#/R-HSA-74255 Guanine + H2O => Xanthine + NH4+ TAS Homo sapiens 29105 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 29105 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 29105 R-HSA-74730 https://reactome.org/PathwayBrowser/#/R-HSA-74730 Insulin degradation TAS Homo sapiens 29105 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 29105 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 29105 R-HSA-880007 https://reactome.org/PathwayBrowser/#/R-HSA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 TAS Homo sapiens 29105 R-HSA-8853686 https://reactome.org/PathwayBrowser/#/R-HSA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 TAS Homo sapiens 29105 R-HSA-8866601 https://reactome.org/PathwayBrowser/#/R-HSA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate TAS Homo sapiens 29105 R-HSA-8867344 https://reactome.org/PathwayBrowser/#/R-HSA-8867344 OMA1 hydrolyses OPA1 TAS Homo sapiens 29105 R-HSA-8876993 https://reactome.org/PathwayBrowser/#/R-HSA-8876993 CBLL1 binds SRC-phosphorylated CDH1 complex TAS Homo sapiens 29105 R-HSA-8877003 https://reactome.org/PathwayBrowser/#/R-HSA-8877003 CBLL1 ubiqutinates the InlA-bound CDH1 complex TAS Homo sapiens 29105 R-HSA-8878787 https://reactome.org/PathwayBrowser/#/R-HSA-8878787 ALPI dimer hydrolyses phosphate monoesters TAS Homo sapiens 29105 R-HSA-8940070 https://reactome.org/PathwayBrowser/#/R-HSA-8940070 NT5E:Zn2+ hydrolyses NAD+ TAS Homo sapiens 29105 R-HSA-8940074 https://reactome.org/PathwayBrowser/#/R-HSA-8940074 NT5E:Zn2+ hydrolyses NMN TAS Homo sapiens 29105 R-HSA-8949649 https://reactome.org/PathwayBrowser/#/R-HSA-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) TAS Homo sapiens 29105 R-HSA-8949659 https://reactome.org/PathwayBrowser/#/R-HSA-8949659 AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU TAS Homo sapiens 29105 R-HSA-8949661 https://reactome.org/PathwayBrowser/#/R-HSA-8949661 C2orf47:AFG3L2 binds the transit peptide of SMDT1 TAS Homo sapiens 29105 R-HSA-8949668 https://reactome.org/PathwayBrowser/#/R-HSA-8949668 YME1L1 proteolyzes unassembled proSMDT1 TAS Homo sapiens 29105 R-HSA-8951723 https://reactome.org/PathwayBrowser/#/R-HSA-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates TAS Homo sapiens 29105 R-HSA-9010034 https://reactome.org/PathwayBrowser/#/R-HSA-9010034 ADAM10:Zn2+:TSPANs cleaves APP(18-770) TAS Homo sapiens 29105 R-HSA-9010074 https://reactome.org/PathwayBrowser/#/R-HSA-9010074 ADAM10:Zn2+:TSPANs translocates from ER lumen to plasma membrane TAS Homo sapiens 29105 R-HSA-9010113 https://reactome.org/PathwayBrowser/#/R-HSA-9010113 ADAM10:Zn2+ binds TSPANs TAS Homo sapiens 29105 R-HSA-9013284 https://reactome.org/PathwayBrowser/#/R-HSA-9013284 NOTCH3-ligand complex is cleaved to produce NEXT3 TAS Homo sapiens 29105 R-HSA-9018862 https://reactome.org/PathwayBrowser/#/R-HSA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 TAS Homo sapiens 29105 R-HSA-9018877 https://reactome.org/PathwayBrowser/#/R-HSA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 TAS Homo sapiens 29105 R-HSA-9020252 https://reactome.org/PathwayBrowser/#/R-HSA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 TAS Homo sapiens 29105 R-HSA-9020253 https://reactome.org/PathwayBrowser/#/R-HSA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 TAS Homo sapiens 29105 R-HSA-9020257 https://reactome.org/PathwayBrowser/#/R-HSA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 TAS Homo sapiens 29105 R-HSA-9020258 https://reactome.org/PathwayBrowser/#/R-HSA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 TAS Homo sapiens 29105 R-HSA-9020270 https://reactome.org/PathwayBrowser/#/R-HSA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 TAS Homo sapiens 29105 R-HSA-9023159 https://reactome.org/PathwayBrowser/#/R-HSA-9023159 Carboxypeptidase E hydrolyzes Insulin(57-89) to yield C-peptide (Insulin(57-87)) IEA Homo sapiens 29105 R-HSA-9023163 https://reactome.org/PathwayBrowser/#/R-HSA-9023163 Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54) IEA Homo sapiens 29105 R-HSA-9023171 https://reactome.org/PathwayBrowser/#/R-HSA-9023171 Insulin secretory granule translocates across the cortical actin network IEA Homo sapiens 29105 R-HSA-9023173 https://reactome.org/PathwayBrowser/#/R-HSA-9023173 Insulin secretory granule docks at the plasma membrane IEA Homo sapiens 29105 R-HSA-9023178 https://reactome.org/PathwayBrowser/#/R-HSA-9023178 PCSK2 cleaves Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) IEA Homo sapiens 29105 R-HSA-9023196 https://reactome.org/PathwayBrowser/#/R-HSA-9023196 PCSK1 cleaves proinsulin to yield Insulin(25-56) and Insulin(57-110) IEA Homo sapiens 29105 R-HSA-9024890 https://reactome.org/PathwayBrowser/#/R-HSA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 TAS Homo sapiens 29105 R-HSA-947514 https://reactome.org/PathwayBrowser/#/R-HSA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 TAS Homo sapiens 29105 R-HSA-947538 https://reactome.org/PathwayBrowser/#/R-HSA-947538 Transfer of sulfur from MOCS3-S-S onto MOCS2A TAS Homo sapiens 29105 R-HSA-9604264 https://reactome.org/PathwayBrowser/#/R-HSA-9604264 ADAM10 cleaves NOTCH4 IEA Homo sapiens 29105 R-HSA-9610152 https://reactome.org/PathwayBrowser/#/R-HSA-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome TAS Homo sapiens 29105 R-HSA-9610153 https://reactome.org/PathwayBrowser/#/R-HSA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF TAS Homo sapiens 29105 R-HSA-9610154 https://reactome.org/PathwayBrowser/#/R-HSA-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs TAS Homo sapiens 29105 R-HSA-9610156 https://reactome.org/PathwayBrowser/#/R-HSA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF TAS Homo sapiens 29105 R-HSA-9610163 https://reactome.org/PathwayBrowser/#/R-HSA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF TAS Homo sapiens 29105 R-HSA-9612980 https://reactome.org/PathwayBrowser/#/R-HSA-9612980 BRAF in Rap1-GTP complex:BRAF complex autophosphorylates IEA Homo sapiens 29105 R-HSA-9638046 https://reactome.org/PathwayBrowser/#/R-HSA-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 29105 R-HSA-9647977 https://reactome.org/PathwayBrowser/#/R-HSA-9647977 ICMT methylates S-Farn RAS proteins TAS Homo sapiens 29105 R-HSA-964958 https://reactome.org/PathwayBrowser/#/R-HSA-964958 2xPDXK:2xZn2+ phosphorylates PXA TAS Homo sapiens 29105 R-HSA-964962 https://reactome.org/PathwayBrowser/#/R-HSA-964962 2xPDKX:2xZn2+ phosphorylates PDX TAS Homo sapiens 29105 R-HSA-964970 https://reactome.org/PathwayBrowser/#/R-HSA-964970 2xPDXK:2xZn2+ phosphorylates PXL TAS Homo sapiens 29105 R-HSA-9656775 https://reactome.org/PathwayBrowser/#/R-HSA-9656775 Cysmethynil binds ICMT:Zn2+ TAS Homo sapiens 29105 R-HSA-9662773 https://reactome.org/PathwayBrowser/#/R-HSA-9662773 ADAM17 binds Zn2+ TAS Homo sapiens 29105 R-HSA-9662818 https://reactome.org/PathwayBrowser/#/R-HSA-9662818 iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane TAS Homo sapiens 29105 R-HSA-9662823 https://reactome.org/PathwayBrowser/#/R-HSA-9662823 PLK2, MAPK14 phosphorylate ADAM17 TAS Homo sapiens 29105 R-HSA-9662837 https://reactome.org/PathwayBrowser/#/R-HSA-9662837 p-S,T-ADAM17(215-827):Zn2+ cleaves CD163 TAS Homo sapiens 29105 R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 29105 R-HSA-9727607 https://reactome.org/PathwayBrowser/#/R-HSA-9727607 MME:Zn2+ binds sacubitrilat TAS Homo sapiens 29105 R-HSA-9731661 https://reactome.org/PathwayBrowser/#/R-HSA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine TAS Homo sapiens 29105 R-HSA-9753944 https://reactome.org/PathwayBrowser/#/R-HSA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys TAS Homo sapiens 29105 R-HSA-975814 https://reactome.org/PathwayBrowser/#/R-HSA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 TAS Homo sapiens 29105 R-HSA-976991 https://reactome.org/PathwayBrowser/#/R-HSA-976991 Prolactin receptor ligands bind the prolactin receptor TAS Homo sapiens 29105 R-HSA-9820566 https://reactome.org/PathwayBrowser/#/R-HSA-9820566 ZnT5 transports zinc into the golgi apparatus TAS Homo sapiens 29105 R-HSA-982810 https://reactome.org/PathwayBrowser/#/R-HSA-982810 JAK2 phosphorylation TAS Homo sapiens 29105 R-HSA-9828639 https://reactome.org/PathwayBrowser/#/R-HSA-9828639 Transcription of respiratory syncytial virus subgenomic positive sense mRNAs TAS Homo sapiens 29105 R-HSA-9830270 https://reactome.org/PathwayBrowser/#/R-HSA-9830270 Protein M2-1 forms tetramers TAS Homo sapiens 29105 R-HSA-9830284 https://reactome.org/PathwayBrowser/#/R-HSA-9830284 Protein M2-1 tetramers bind protein P tetramer TAS Homo sapiens 29105 R-HSA-9830848 https://reactome.org/PathwayBrowser/#/R-HSA-9830848 L protein acts as a cap N7 methyltransferase to modify RSV mRNAs TAS Homo sapiens 29105 R-HSA-9831948 https://reactome.org/PathwayBrowser/#/R-HSA-9831948 P:PP1 dephosphorylates M2-1 TAS Homo sapiens 29105 R-HSA-9832006 https://reactome.org/PathwayBrowser/#/R-HSA-9832006 Nascent M2-1 binds Zn2+ TAS Homo sapiens 29105 R-HSA-9832009 https://reactome.org/PathwayBrowser/#/R-HSA-9832009 M2-1 tetramer gets phosphorylated TAS Homo sapiens 29105 R-HSA-9832040 https://reactome.org/PathwayBrowser/#/R-HSA-9832040 M2-1 localizes to nucleus TAS Homo sapiens 29105 R-HSA-9833031 https://reactome.org/PathwayBrowser/#/R-HSA-9833031 Polyadenylation of respiratory syncytial virus subgenomic positive-sense mRNAs TAS Homo sapiens 29105 R-HSA-9833933 https://reactome.org/PathwayBrowser/#/R-HSA-9833933 RdRP binds hRSV nucleocapsid TAS Homo sapiens 29105 R-HSA-9834003 https://reactome.org/PathwayBrowser/#/R-HSA-9834003 L protein acts as a cap 2'-O-methyltransferase to modify RSV mRNAs TAS Homo sapiens 29105 R-HSA-9834719 https://reactome.org/PathwayBrowser/#/R-HSA-9834719 Synthesis of negative sense genomic RNA of respiratory syncytial virus TAS Homo sapiens 29105 R-HSA-9834736 https://reactome.org/PathwayBrowser/#/R-HSA-9834736 Synthesis of antigenomic RNA of human respiratory syncytial virus TAS Homo sapiens 29105 R-HSA-9835151 https://reactome.org/PathwayBrowser/#/R-HSA-9835151 Packaging of RdRP complex with replicated hRSV A nucleocapsid TAS Homo sapiens 29105 R-HSA-9835165 https://reactome.org/PathwayBrowser/#/R-HSA-9835165 Formation of hRSV A matrix lattice TAS Homo sapiens 29105 R-HSA-9835171 https://reactome.org/PathwayBrowser/#/R-HSA-9835171 Budding of hRSV A virions from infected cell TAS Homo sapiens 29105 R-HSA-9836227 https://reactome.org/PathwayBrowser/#/R-HSA-9836227 RSV F binds TLR4:LY96:CD14 TAS Homo sapiens 29105 R-HSA-9836467 https://reactome.org/PathwayBrowser/#/R-HSA-9836467 F protein binds NCL on host cell surface TAS Homo sapiens 29105 R-HSA-9836468 https://reactome.org/PathwayBrowser/#/R-HSA-9836468 G protein binds CX3CR1 on host cell surface TAS Homo sapiens 29105 R-HSA-9837376 https://reactome.org/PathwayBrowser/#/R-HSA-9837376 RSV G binds CD209,CLEC4M TAS Homo sapiens 29105 R-HSA-9837392 https://reactome.org/PathwayBrowser/#/R-HSA-9837392 Packaging of antigenomic RNA of human respiratory syncytial virus TAS Homo sapiens 29105 R-HSA-9837511 https://reactome.org/PathwayBrowser/#/R-HSA-9837511 Abortive replication of hRSV A TAS Homo sapiens 29105 R-HSA-9837543 https://reactome.org/PathwayBrowser/#/R-HSA-9837543 hRSV A enters host cell through membrane fusion TAS Homo sapiens 29105 R-HSA-9837625 https://reactome.org/PathwayBrowser/#/R-HSA-9837625 hRSV A enters host cell through macropinocytosis TAS Homo sapiens 29105 R-HSA-9837707 https://reactome.org/PathwayBrowser/#/R-HSA-9837707 Release of hRSV A nucleocapsid from macropinosome TAS Homo sapiens 29105 R-HSA-9838627 https://reactome.org/PathwayBrowser/#/R-HSA-9838627 AFG3L2 binds mitochondrial inner membrane proteins TAS Homo sapiens 29105 R-HSA-9839053 https://reactome.org/PathwayBrowser/#/R-HSA-9839053 AFG3L2:SPG7 binds SMDT1 (EMRE) TAS Homo sapiens 29105 R-HSA-9839059 https://reactome.org/PathwayBrowser/#/R-HSA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) TAS Homo sapiens 29105 R-HSA-9839064 https://reactome.org/PathwayBrowser/#/R-HSA-9839064 YME1L1 binds mitochondrial inner membrane proteins IEA Homo sapiens 29105 R-HSA-9839105 https://reactome.org/PathwayBrowser/#/R-HSA-9839105 AFG3L2 degrades mitochondrial matrix proteins TAS Homo sapiens 29105 R-HSA-9839113 https://reactome.org/PathwayBrowser/#/R-HSA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins TAS Homo sapiens 29105 R-HSA-9839146 https://reactome.org/PathwayBrowser/#/R-HSA-9839146 YME1L1 degrades mitochondrial inner membrane proteins IEA Homo sapiens 29105 R-HSA-9839149 https://reactome.org/PathwayBrowser/#/R-HSA-9839149 AFG3L2 binds mitochondrial matrix proteins TAS Homo sapiens 29105 R-HSA-9839751 https://reactome.org/PathwayBrowser/#/R-HSA-9839751 YME1L1 degrades mitochondrial intermembrane space proteins IEA Homo sapiens 29105 R-HSA-9839772 https://reactome.org/PathwayBrowser/#/R-HSA-9839772 YME1L1 binds mitochondrial intermembrane space proteins IEA Homo sapiens 29105 R-HSA-9840408 https://reactome.org/PathwayBrowser/#/R-HSA-9840408 OMA1 cleaves DELE1 TAS Homo sapiens 29105 R-HSA-9840532 https://reactome.org/PathwayBrowser/#/R-HSA-9840532 OMA1 self-cleaves IEA Homo sapiens 29105 R-HSA-9840564 https://reactome.org/PathwayBrowser/#/R-HSA-9840564 OMA1 hydrolyzes YME1L1 TAS Homo sapiens 29105 R-HSA-9845143 https://reactome.org/PathwayBrowser/#/R-HSA-9845143 F inhibitors bind F on RSV virion TAS Homo sapiens 29105 R-HSA-9845222 https://reactome.org/PathwayBrowser/#/R-HSA-9845222 Lumicitabine binds RdRP on nucleocapsid TAS Homo sapiens 29105 R-HSA-9854463 https://reactome.org/PathwayBrowser/#/R-HSA-9854463 SIRT3 deacetylates AcK-IDH2 dimer TAS Homo sapiens 29105 R-HSA-9861626 https://reactome.org/PathwayBrowser/#/R-HSA-9861626 SIRT4 cleaves lipoyl from DLAT TAS Homo sapiens 29105 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 29105 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 29105 R-MMU-1170539 https://reactome.org/PathwayBrowser/#/R-MMU-1170539 Prolactin receptor is internalized IEA Mus musculus 29105 R-MMU-1237045 https://reactome.org/PathwayBrowser/#/R-MMU-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Mus musculus 29105 R-MMU-1237047 https://reactome.org/PathwayBrowser/#/R-MMU-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Mus musculus 29105 R-MMU-1237059 https://reactome.org/PathwayBrowser/#/R-MMU-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Mus musculus 29105 R-MMU-1237081 https://reactome.org/PathwayBrowser/#/R-MMU-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Mus musculus 29105 R-MMU-1370500 https://reactome.org/PathwayBrowser/#/R-MMU-1370500 PRLR binds SCF beta-TrCP complex IEA Mus musculus 29105 R-MMU-1370505 https://reactome.org/PathwayBrowser/#/R-MMU-1370505 PRLR is phosphorylated at Ser-349 IEA Mus musculus 29105 R-MMU-1474184 https://reactome.org/PathwayBrowser/#/R-MMU-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Mus musculus 29105 R-MMU-1475017 https://reactome.org/PathwayBrowser/#/R-MMU-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Mus musculus 29105 R-MMU-1475022 https://reactome.org/PathwayBrowser/#/R-MMU-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Mus musculus 29105 R-MMU-1475025 https://reactome.org/PathwayBrowser/#/R-MMU-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Mus musculus 29105 R-MMU-1475026 https://reactome.org/PathwayBrowser/#/R-MMU-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Mus musculus 29105 R-MMU-1475028 https://reactome.org/PathwayBrowser/#/R-MMU-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Mus musculus 29105 R-MMU-1475032 https://reactome.org/PathwayBrowser/#/R-MMU-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Mus musculus 29105 R-MMU-1475422 https://reactome.org/PathwayBrowser/#/R-MMU-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Mus musculus 29105 R-MMU-1475435 https://reactome.org/PathwayBrowser/#/R-MMU-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Mus musculus 29105 R-MMU-1475436 https://reactome.org/PathwayBrowser/#/R-MMU-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Mus musculus 29105 R-MMU-1497784 https://reactome.org/PathwayBrowser/#/R-MMU-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Mus musculus 29105 R-MMU-1497796 https://reactome.org/PathwayBrowser/#/R-MMU-1497796 BH2 binding can lead to eNOS uncoupling IEA Mus musculus 29105 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 29105 R-MMU-158354 https://reactome.org/PathwayBrowser/#/R-MMU-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer IEA Mus musculus 29105 R-MMU-158941 https://reactome.org/PathwayBrowser/#/R-MMU-158941 plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein IEA Mus musculus 29105 R-MMU-1614605 https://reactome.org/PathwayBrowser/#/R-MMU-1614605 Persulfide sulfur is dioxygenated IEA Mus musculus 29105 R-MMU-1614654 https://reactome.org/PathwayBrowser/#/R-MMU-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Mus musculus 29105 R-MMU-1671687 https://reactome.org/PathwayBrowser/#/R-MMU-1671687 PRLR activation IEA Mus musculus 29105 R-MMU-1675473 https://reactome.org/PathwayBrowser/#/R-MMU-1675473 SH2B binds JAK2 IEA Mus musculus 29105 R-MMU-174374 https://reactome.org/PathwayBrowser/#/R-MMU-174374 MTR transfers CH3 from MeCbl to HCYS IEA Mus musculus 29105 R-MMU-179883 https://reactome.org/PathwayBrowser/#/R-MMU-179883 Mouse pro-EGF is cleaved by ADAM sheddases TAS Mus musculus 29105 R-MMU-189384 https://reactome.org/PathwayBrowser/#/R-MMU-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Mus musculus 29105 R-MMU-189439 https://reactome.org/PathwayBrowser/#/R-MMU-189439 ALAD condenses 2 dALAs to form PBG IEA Mus musculus 29105 R-MMU-193679 https://reactome.org/PathwayBrowser/#/R-MMU-193679 alpha-secretase cleaves the p75NTR extracellular domain IEA Mus musculus 29105 R-MMU-197198 https://reactome.org/PathwayBrowser/#/R-MMU-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Mus musculus 29105 R-MMU-200512 https://reactome.org/PathwayBrowser/#/R-MMU-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 29105 R-MMU-202110 https://reactome.org/PathwayBrowser/#/R-MMU-202110 eNOS:Caveolin-1 complex binds to CaM IEA Mus musculus 29105 R-MMU-202111 https://reactome.org/PathwayBrowser/#/R-MMU-202111 AKT1 phosphorylates eNOS IEA Mus musculus 29105 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 29105 R-MMU-202129 https://reactome.org/PathwayBrowser/#/R-MMU-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Mus musculus 29105 R-MMU-202132 https://reactome.org/PathwayBrowser/#/R-MMU-202132 depalmitoylated eNOS translocates from plasma membrane IEA Mus musculus 29105 R-MMU-202137 https://reactome.org/PathwayBrowser/#/R-MMU-202137 AKT1 binds eNOS complex via HSP90 IEA Mus musculus 29105 R-MMU-202144 https://reactome.org/PathwayBrowser/#/R-MMU-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Mus musculus 29105 R-MMU-2022368 https://reactome.org/PathwayBrowser/#/R-MMU-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Mus musculus 29105 R-MMU-2022378 https://reactome.org/PathwayBrowser/#/R-MMU-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Mus musculus 29105 R-MMU-2022379 https://reactome.org/PathwayBrowser/#/R-MMU-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Mus musculus 29105 R-MMU-2022396 https://reactome.org/PathwayBrowser/#/R-MMU-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Mus musculus 29105 R-MMU-2022398 https://reactome.org/PathwayBrowser/#/R-MMU-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Mus musculus 29105 R-MMU-2022399 https://reactome.org/PathwayBrowser/#/R-MMU-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Mus musculus 29105 R-MMU-2022405 https://reactome.org/PathwayBrowser/#/R-MMU-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 29105 R-MMU-2025890 https://reactome.org/PathwayBrowser/#/R-MMU-2025890 Calcineurin binds NFATC1,2,3 IEA Mus musculus 29105 R-MMU-2025936 https://reactome.org/PathwayBrowser/#/R-MMU-2025936 Calcineurin Dephosphorylates Nfatc2 TAS Mus musculus 29105 R-MMU-2028294 https://reactome.org/PathwayBrowser/#/R-MMU-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Mus musculus 29105 R-MMU-203553 https://reactome.org/PathwayBrowser/#/R-MMU-203553 eNOS binds NOSIP IEA Mus musculus 29105 R-MMU-203613 https://reactome.org/PathwayBrowser/#/R-MMU-203613 depalmitoylation of eNOS IEA Mus musculus 29105 R-MMU-203625 https://reactome.org/PathwayBrowser/#/R-MMU-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Mus musculus 29105 R-MMU-203662 https://reactome.org/PathwayBrowser/#/R-MMU-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Mus musculus 29105 R-MMU-203680 https://reactome.org/PathwayBrowser/#/R-MMU-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Mus musculus 29105 R-MMU-203700 https://reactome.org/PathwayBrowser/#/R-MMU-203700 eNOS translocation from Golgi to Caveolae IEA Mus musculus 29105 R-MMU-203712 https://reactome.org/PathwayBrowser/#/R-MMU-203712 eNOS associates with Caveolin-1 IEA Mus musculus 29105 R-MMU-203716 https://reactome.org/PathwayBrowser/#/R-MMU-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Mus musculus 29105 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 29105 R-MMU-2161187 https://reactome.org/PathwayBrowser/#/R-MMU-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Mus musculus 29105 R-MMU-2161195 https://reactome.org/PathwayBrowser/#/R-MMU-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Mus musculus 29105 R-MMU-2162078 https://reactome.org/PathwayBrowser/#/R-MMU-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Mus musculus 29105 R-MMU-216806 https://reactome.org/PathwayBrowser/#/R-MMU-216806 Processing of Proinsulin to Insulin TAS Mus musculus 29105 R-MMU-216883 https://reactome.org/PathwayBrowser/#/R-MMU-216883 Exocytosis of Insulin TAS Mus musculus 29105 R-MMU-264758 https://reactome.org/PathwayBrowser/#/R-MMU-264758 BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 IEA Mus musculus 29105 R-MMU-264976 https://reactome.org/PathwayBrowser/#/R-MMU-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Mus musculus 29105 R-MMU-265153 https://reactome.org/PathwayBrowser/#/R-MMU-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Mus musculus 29105 R-MMU-265682 https://reactome.org/PathwayBrowser/#/R-MMU-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Mus musculus 29105 R-MMU-266012 https://reactome.org/PathwayBrowser/#/R-MMU-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Mus musculus 29105 R-MMU-266072 https://reactome.org/PathwayBrowser/#/R-MMU-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Mus musculus 29105 R-MMU-2730849 https://reactome.org/PathwayBrowser/#/R-MMU-2730849 Calcineurin binds and dephosphorylates NFAT IEA Mus musculus 29105 R-MMU-2730867 https://reactome.org/PathwayBrowser/#/R-MMU-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Mus musculus 29105 R-MMU-2730872 https://reactome.org/PathwayBrowser/#/R-MMU-2730872 Activation of Calcineurin IEA Mus musculus 29105 R-MMU-3149518 https://reactome.org/PathwayBrowser/#/R-MMU-3149518 MTRR reduces cob(II)alamin to meCbl IEA Mus musculus 29105 R-MMU-3149539 https://reactome.org/PathwayBrowser/#/R-MMU-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Mus musculus 29105 R-MMU-3204318 https://reactome.org/PathwayBrowser/#/R-MMU-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Mus musculus 29105 R-MMU-3299682 https://reactome.org/PathwayBrowser/#/R-MMU-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Mus musculus 29105 R-MMU-3299691 https://reactome.org/PathwayBrowser/#/R-MMU-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Mus musculus 29105 R-MMU-3299753 https://reactome.org/PathwayBrowser/#/R-MMU-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Mus musculus 29105 R-MMU-3371385 https://reactome.org/PathwayBrowser/#/R-MMU-3371385 TNF-α is cleaved by ADAM17 (TACE) IEA Mus musculus 29105 R-MMU-3697860 https://reactome.org/PathwayBrowser/#/R-MMU-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Mus musculus 29105 R-MMU-3697899 https://reactome.org/PathwayBrowser/#/R-MMU-3697899 Atp7a transfers Cu from Atox1 to Sod3 TAS Mus musculus 29105 R-MMU-3777112 https://reactome.org/PathwayBrowser/#/R-MMU-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Mus musculus 29105 R-MMU-3780959 https://reactome.org/PathwayBrowser/#/R-MMU-3780959 Sod1 apoenzyme binds Ccs TAS Mus musculus 29105 R-MMU-3780963 https://reactome.org/PathwayBrowser/#/R-MMU-3780963 Ccs transfers Cu to Sod1 TAS Mus musculus 29105 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 29105 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 29105 R-MMU-428262 https://reactome.org/PathwayBrowser/#/R-MMU-428262 ACER3 hydrolyzes phytoceramide IEA Mus musculus 29105 R-MMU-435171 https://reactome.org/PathwayBrowser/#/R-MMU-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Mus musculus 29105 R-MMU-435366 https://reactome.org/PathwayBrowser/#/R-MMU-435366 ZnT1 mediates the efflux of zinc from the cell IEA Mus musculus 29105 R-MMU-437085 https://reactome.org/PathwayBrowser/#/R-MMU-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Mus musculus 29105 R-MMU-437092 https://reactome.org/PathwayBrowser/#/R-MMU-437092 Znt3 transports zinc into synaptic vesicles TAS Mus musculus 29105 R-MMU-437136 https://reactome.org/PathwayBrowser/#/R-MMU-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Mus musculus 29105 R-MMU-437139 https://reactome.org/PathwayBrowser/#/R-MMU-437139 ZnT8 transports zinc into the Golgi apparatus IEA Mus musculus 29105 R-MMU-442317 https://reactome.org/PathwayBrowser/#/R-MMU-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Mus musculus 29105 R-MMU-442319 https://reactome.org/PathwayBrowser/#/R-MMU-442319 mZIP5 mediates zinc uptake by cells TAS Mus musculus 29105 R-MMU-442387 https://reactome.org/PathwayBrowser/#/R-MMU-442387 ZIP8 mediates zinc influx into cells IEA Mus musculus 29105 R-MMU-442393 https://reactome.org/PathwayBrowser/#/R-MMU-442393 ZIP7 mediates zinc efflux from the endoplasmic reticulum IEA Mus musculus 29105 R-MMU-442422 https://reactome.org/PathwayBrowser/#/R-MMU-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Mus musculus 29105 R-MMU-444572 https://reactome.org/PathwayBrowser/#/R-MMU-444572 Zinc is an agonist of GPR39 IEA Mus musculus 29105 R-MMU-4551451 https://reactome.org/PathwayBrowser/#/R-MMU-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Mus musculus 29105 R-MMU-4551465 https://reactome.org/PathwayBrowser/#/R-MMU-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Mus musculus 29105 R-MMU-4837364 https://reactome.org/PathwayBrowser/#/R-MMU-4837364 Secretion of SOD3 IEA Mus musculus 29105 R-MMU-5362564 https://reactome.org/PathwayBrowser/#/R-MMU-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Mus musculus 29105 R-MMU-5433067 https://reactome.org/PathwayBrowser/#/R-MMU-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Mus musculus 29105 R-MMU-5433074 https://reactome.org/PathwayBrowser/#/R-MMU-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 29105 R-MMU-5652195 https://reactome.org/PathwayBrowser/#/R-MMU-5652195 SORD oxidizes D-sorbitol to Fru IEA Mus musculus 29105 R-MMU-5660470 https://reactome.org/PathwayBrowser/#/R-MMU-5660470 Mtf1 dimer:12Zn2+ binds Csrp1 gene TAS Mus musculus 29105 R-MMU-5660533 https://reactome.org/PathwayBrowser/#/R-MMU-5660533 Expression of Csrp1 TAS Mus musculus 29105 R-MMU-5661217 https://reactome.org/PathwayBrowser/#/R-MMU-5661217 MT1A binds zinc IEA Mus musculus 29105 R-MMU-5662471 https://reactome.org/PathwayBrowser/#/R-MMU-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Mus musculus 29105 R-MMU-5662606 https://reactome.org/PathwayBrowser/#/R-MMU-5662606 MT3 binds zinc IEA Mus musculus 29105 R-MMU-5662613 https://reactome.org/PathwayBrowser/#/R-MMU-5662613 MT3 exchanges zinc for copper IEA Mus musculus 29105 R-MMU-5662634 https://reactome.org/PathwayBrowser/#/R-MMU-5662634 Mt4 binds zinc TAS Mus musculus 29105 R-MMU-5662660 https://reactome.org/PathwayBrowser/#/R-MMU-5662660 Dopachrome is transformed to DHICA by DCT IEA Mus musculus 29105 R-MMU-5682586 https://reactome.org/PathwayBrowser/#/R-MMU-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Mus musculus 29105 R-MMU-5682588 https://reactome.org/PathwayBrowser/#/R-MMU-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Mus musculus 29105 R-MMU-5682598 https://reactome.org/PathwayBrowser/#/R-MMU-5682598 ATM phosphorylates HERC2 IEA Mus musculus 29105 R-MMU-5682607 https://reactome.org/PathwayBrowser/#/R-MMU-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Mus musculus 29105 R-MMU-5682629 https://reactome.org/PathwayBrowser/#/R-MMU-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Mus musculus 29105 R-MMU-5682858 https://reactome.org/PathwayBrowser/#/R-MMU-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Mus musculus 29105 R-MMU-5682863 https://reactome.org/PathwayBrowser/#/R-MMU-5682863 RNF168 binds DNA DSBs IEA Mus musculus 29105 R-MMU-5683077 https://reactome.org/PathwayBrowser/#/R-MMU-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Mus musculus 29105 R-MMU-5683384 https://reactome.org/PathwayBrowser/#/R-MMU-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Mus musculus 29105 R-MMU-5683385 https://reactome.org/PathwayBrowser/#/R-MMU-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Mus musculus 29105 R-MMU-5683405 https://reactome.org/PathwayBrowser/#/R-MMU-5683405 PPP5C dephosphorylates TP53BP1 IEA Mus musculus 29105 R-MMU-5683425 https://reactome.org/PathwayBrowser/#/R-MMU-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Mus musculus 29105 R-MMU-5683735 https://reactome.org/PathwayBrowser/#/R-MMU-5683735 CHEK2 is recruited to DNA DSBs IEA Mus musculus 29105 R-MMU-5683801 https://reactome.org/PathwayBrowser/#/R-MMU-5683801 CHEK2 phosphorylates BRCA1 IEA Mus musculus 29105 R-MMU-5684052 https://reactome.org/PathwayBrowser/#/R-MMU-5684052 PIAS4 SUMOylates MDC1 IEA Mus musculus 29105 R-MMU-5684071 https://reactome.org/PathwayBrowser/#/R-MMU-5684071 RNF4 ubiquitinates MDC1 IEA Mus musculus 29105 R-MMU-5686685 https://reactome.org/PathwayBrowser/#/R-MMU-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Mus musculus 29105 R-MMU-5686704 https://reactome.org/PathwayBrowser/#/R-MMU-5686704 Activated ATM phosphorylates DCLRE1C IEA Mus musculus 29105 R-MMU-5686900 https://reactome.org/PathwayBrowser/#/R-MMU-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Mus musculus 29105 R-MMU-5688276 https://reactome.org/PathwayBrowser/#/R-MMU-5688276 SIRT4 transfers ADPRib to GLUD IEA Mus musculus 29105 R-MMU-5688289 https://reactome.org/PathwayBrowser/#/R-MMU-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Mus musculus 29105 R-MMU-5688294 https://reactome.org/PathwayBrowser/#/R-MMU-5688294 SIRT5 deacetylates Cytochrome C IEA Mus musculus 29105 R-MMU-5691507 https://reactome.org/PathwayBrowser/#/R-MMU-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Mus musculus 29105 R-MMU-5692237 https://reactome.org/PathwayBrowser/#/R-MMU-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Mus musculus 29105 R-MMU-5693551 https://reactome.org/PathwayBrowser/#/R-MMU-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Mus musculus 29105 R-MMU-5693566 https://reactome.org/PathwayBrowser/#/R-MMU-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Mus musculus 29105 R-MMU-5693599 https://reactome.org/PathwayBrowser/#/R-MMU-5693599 Association of Ku heterodimer with ends of DNA double-strand break IEA Mus musculus 29105 R-MMU-5694071 https://reactome.org/PathwayBrowser/#/R-MMU-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Mus musculus 29105 R-MMU-5694082 https://reactome.org/PathwayBrowser/#/R-MMU-5694082 XK:KEL:Zn2+ cleaves EDN3 IEA Mus musculus 29105 R-MMU-5696838 https://reactome.org/PathwayBrowser/#/R-MMU-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Mus musculus 29105 R-MMU-6783221 https://reactome.org/PathwayBrowser/#/R-MMU-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Mus musculus 29105 R-MMU-6788650 https://reactome.org/PathwayBrowser/#/R-MMU-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Mus musculus 29105 R-MMU-6789072 https://reactome.org/PathwayBrowser/#/R-MMU-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Mus musculus 29105 R-MMU-6798474 https://reactome.org/PathwayBrowser/#/R-MMU-6798474 S100A8:S100A9 binds Zn2+ IEA Mus musculus 29105 R-MMU-6798563 https://reactome.org/PathwayBrowser/#/R-MMU-6798563 Mt2 binds zinc TAS Mus musculus 29105 R-MMU-6799545 https://reactome.org/PathwayBrowser/#/R-MMU-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Mus musculus 29105 R-MMU-6799581 https://reactome.org/PathwayBrowser/#/R-MMU-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Mus musculus 29105 R-MMU-6799959 https://reactome.org/PathwayBrowser/#/R-MMU-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Mus musculus 29105 R-MMU-6799977 https://reactome.org/PathwayBrowser/#/R-MMU-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Mus musculus 29105 R-MMU-69891 https://reactome.org/PathwayBrowser/#/R-MMU-69891 Phosphorylation and activation of CHEK2 by ATM IEA Mus musculus 29105 R-MMU-71707 https://reactome.org/PathwayBrowser/#/R-MMU-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Mus musculus 29105 R-MMU-73589 https://reactome.org/PathwayBrowser/#/R-MMU-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Mus musculus 29105 R-MMU-73591 https://reactome.org/PathwayBrowser/#/R-MMU-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Mus musculus 29105 R-MMU-73608 https://reactome.org/PathwayBrowser/#/R-MMU-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Mus musculus 29105 R-MMU-73618 https://reactome.org/PathwayBrowser/#/R-MMU-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Mus musculus 29105 R-MMU-73620 https://reactome.org/PathwayBrowser/#/R-MMU-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Mus musculus 29105 R-MMU-74255 https://reactome.org/PathwayBrowser/#/R-MMU-74255 Guanine + H2O => Xanthine + NH4+ IEA Mus musculus 29105 R-MMU-74730 https://reactome.org/PathwayBrowser/#/R-MMU-74730 Insulin degradation IEA Mus musculus 29105 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 29105 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 29105 R-MMU-880007 https://reactome.org/PathwayBrowser/#/R-MMU-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Mus musculus 29105 R-MMU-8853686 https://reactome.org/PathwayBrowser/#/R-MMU-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Mus musculus 29105 R-MMU-8866601 https://reactome.org/PathwayBrowser/#/R-MMU-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Mus musculus 29105 R-MMU-8867344 https://reactome.org/PathwayBrowser/#/R-MMU-8867344 OMA1 hydrolyses OPA1 IEA Mus musculus 29105 R-MMU-8878787 https://reactome.org/PathwayBrowser/#/R-MMU-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Mus musculus 29105 R-MMU-8940070 https://reactome.org/PathwayBrowser/#/R-MMU-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Mus musculus 29105 R-MMU-8940074 https://reactome.org/PathwayBrowser/#/R-MMU-8940074 NT5E:Zn2+ hydrolyses NMN IEA Mus musculus 29105 R-MMU-8949649 https://reactome.org/PathwayBrowser/#/R-MMU-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) IEA Mus musculus 29105 R-MMU-8949659 https://reactome.org/PathwayBrowser/#/R-MMU-8949659 AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU IEA Mus musculus 29105 R-MMU-8949661 https://reactome.org/PathwayBrowser/#/R-MMU-8949661 C2orf47:AFG3L2 binds the transit peptide of SMDT1 IEA Mus musculus 29105 R-MMU-8949668 https://reactome.org/PathwayBrowser/#/R-MMU-8949668 YME1L1 proteolyzes unassembled proSMDT1 IEA Mus musculus 29105 R-MMU-8951723 https://reactome.org/PathwayBrowser/#/R-MMU-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Mus musculus 29105 R-MMU-9013284 https://reactome.org/PathwayBrowser/#/R-MMU-9013284 NOTCH3-ligand complex is cleaved to produce NEXT3 IEA Mus musculus 29105 R-MMU-9018862 https://reactome.org/PathwayBrowser/#/R-MMU-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Mus musculus 29105 R-MMU-9018877 https://reactome.org/PathwayBrowser/#/R-MMU-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Mus musculus 29105 R-MMU-9020252 https://reactome.org/PathwayBrowser/#/R-MMU-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Mus musculus 29105 R-MMU-9020253 https://reactome.org/PathwayBrowser/#/R-MMU-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Mus musculus 29105 R-MMU-9020257 https://reactome.org/PathwayBrowser/#/R-MMU-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Mus musculus 29105 R-MMU-9020258 https://reactome.org/PathwayBrowser/#/R-MMU-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Mus musculus 29105 R-MMU-9020270 https://reactome.org/PathwayBrowser/#/R-MMU-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Mus musculus 29105 R-MMU-9024890 https://reactome.org/PathwayBrowser/#/R-MMU-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Mus musculus 29105 R-MMU-947514 https://reactome.org/PathwayBrowser/#/R-MMU-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Mus musculus 29105 R-MMU-9610152 https://reactome.org/PathwayBrowser/#/R-MMU-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Mus musculus 29105 R-MMU-9610153 https://reactome.org/PathwayBrowser/#/R-MMU-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Mus musculus 29105 R-MMU-9610154 https://reactome.org/PathwayBrowser/#/R-MMU-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Mus musculus 29105 R-MMU-9610156 https://reactome.org/PathwayBrowser/#/R-MMU-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Mus musculus 29105 R-MMU-9610163 https://reactome.org/PathwayBrowser/#/R-MMU-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Mus musculus 29105 R-MMU-9638046 https://reactome.org/PathwayBrowser/#/R-MMU-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 29105 R-MMU-9647977 https://reactome.org/PathwayBrowser/#/R-MMU-9647977 ICMT methylates S-Farn RAS proteins IEA Mus musculus 29105 R-MMU-964958 https://reactome.org/PathwayBrowser/#/R-MMU-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Mus musculus 29105 R-MMU-964962 https://reactome.org/PathwayBrowser/#/R-MMU-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Mus musculus 29105 R-MMU-964970 https://reactome.org/PathwayBrowser/#/R-MMU-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Mus musculus 29105 R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 29105 R-MMU-9727607 https://reactome.org/PathwayBrowser/#/R-MMU-9727607 MME:Zn2+ binds sacubitrilat IEA Mus musculus 29105 R-MMU-9731661 https://reactome.org/PathwayBrowser/#/R-MMU-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Mus musculus 29105 R-MMU-9753944 https://reactome.org/PathwayBrowser/#/R-MMU-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Mus musculus 29105 R-MMU-975814 https://reactome.org/PathwayBrowser/#/R-MMU-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Mus musculus 29105 R-MMU-976991 https://reactome.org/PathwayBrowser/#/R-MMU-976991 Prolactin receptor ligands bind the prolactin receptor IEA Mus musculus 29105 R-MMU-9820566 https://reactome.org/PathwayBrowser/#/R-MMU-9820566 ZnT5 transports zinc into the golgi apparatus IEA Mus musculus 29105 R-MMU-982810 https://reactome.org/PathwayBrowser/#/R-MMU-982810 JAK2 phosphorylation IEA Mus musculus 29105 R-MMU-9838627 https://reactome.org/PathwayBrowser/#/R-MMU-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Mus musculus 29105 R-MMU-9839053 https://reactome.org/PathwayBrowser/#/R-MMU-9839053 AFG3L2:SPG7 binds SMDT1 (EMRE) IEA Mus musculus 29105 R-MMU-9839059 https://reactome.org/PathwayBrowser/#/R-MMU-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Mus musculus 29105 R-MMU-9839105 https://reactome.org/PathwayBrowser/#/R-MMU-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Mus musculus 29105 R-MMU-9839113 https://reactome.org/PathwayBrowser/#/R-MMU-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Mus musculus 29105 R-MMU-9839149 https://reactome.org/PathwayBrowser/#/R-MMU-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Mus musculus 29105 R-MMU-9840408 https://reactome.org/PathwayBrowser/#/R-MMU-9840408 OMA1 cleaves DELE1 IEA Mus musculus 29105 R-MMU-9840534 https://reactome.org/PathwayBrowser/#/R-MMU-9840534 Oma1 self-cleaves TAS Mus musculus 29105 R-MMU-9840564 https://reactome.org/PathwayBrowser/#/R-MMU-9840564 OMA1 hydrolyzes YME1L1 IEA Mus musculus 29105 R-MMU-9854463 https://reactome.org/PathwayBrowser/#/R-MMU-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Mus musculus 29105 R-MMU-9861626 https://reactome.org/PathwayBrowser/#/R-MMU-9861626 SIRT4 cleaves lipoyl from DLAT IEA Mus musculus 29105 R-MTU-879245 https://reactome.org/PathwayBrowser/#/R-MTU-879245 mycothiol binds formaldehyde and is dehydrogenated TAS Mycobacterium tuberculosis 29105 R-MTU-879281 https://reactome.org/PathwayBrowser/#/R-MTU-879281 mycothiol is cleaved to acetylcysteine and glucosaminylinositol TAS Mycobacterium tuberculosis 29105 R-MTU-879311 https://reactome.org/PathwayBrowser/#/R-MTU-879311 mycothiol S-conjugate is cleaved into mercapturic acid and GlcN-Ins TAS Mycobacterium tuberculosis 29105 R-MTU-879319 https://reactome.org/PathwayBrowser/#/R-MTU-879319 glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol TAS Mycobacterium tuberculosis 29105 R-MTU-879327 https://reactome.org/PathwayBrowser/#/R-MTU-879327 acetylglucosamine-inositol is deacetylated by Mca TAS Mycobacterium tuberculosis 29105 R-MTU-879331 https://reactome.org/PathwayBrowser/#/R-MTU-879331 glucose-6-phosphate is converted to inositol-1-phosphate TAS Mycobacterium tuberculosis 29105 R-MTU-936747 https://reactome.org/PathwayBrowser/#/R-MTU-936747 cleavage of L-cysteine from carrier protein TAS Mycobacterium tuberculosis 29105 R-NUL-1251988 https://reactome.org/PathwayBrowser/#/R-NUL-1251988 Cleavage of P-ERBB4jmA isoforms by Adam17 TAS Homo sapiens 29105 R-NUL-2063915 https://reactome.org/PathwayBrowser/#/R-NUL-2063915 ADAM17 cleaves Notch1 at S2 TAS Mus musculus 29105 R-NUL-209162 https://reactome.org/PathwayBrowser/#/R-NUL-209162 Murine ADAM10 cleaves Notch at the S2 site producing transmembrane spanning NEXT and ligand-bound NECD TAS Mus musculus 29105 R-NUL-9023165 https://reactome.org/PathwayBrowser/#/R-NUL-9023165 Pcsk1 (rat) cleaves human proinsulin to yield Insulin(25-56) and Insulin(57-110) TAS Homo sapiens 29105 R-NUL-9023166 https://reactome.org/PathwayBrowser/#/R-NUL-9023166 Carboxypeptidase E (rat Carboxypeptidase H) cleaves Insulin(25-56) to yield Insulin(25-54) TAS Homo sapiens 29105 R-NUL-9023180 https://reactome.org/PathwayBrowser/#/R-NUL-9023180 Pcsk2 (rat) cleaves human Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) TAS Homo sapiens 29105 R-NUL-9023186 https://reactome.org/PathwayBrowser/#/R-NUL-9023186 Carboxypeptidase E (rat Carboxypeptidase H) cleaves C-peptide (Insulin(57-89)) to yield C-peptide (Insulin(57-87)) TAS Homo sapiens 29105 R-PFA-1474184 https://reactome.org/PathwayBrowser/#/R-PFA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Plasmodium falciparum 29105 R-PFA-1475022 https://reactome.org/PathwayBrowser/#/R-PFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Plasmodium falciparum 29105 R-PFA-1475026 https://reactome.org/PathwayBrowser/#/R-PFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Plasmodium falciparum 29105 R-PFA-1475028 https://reactome.org/PathwayBrowser/#/R-PFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Plasmodium falciparum 29105 R-PFA-1475032 https://reactome.org/PathwayBrowser/#/R-PFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Plasmodium falciparum 29105 R-PFA-1475435 https://reactome.org/PathwayBrowser/#/R-PFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Plasmodium falciparum 29105 R-PFA-1475436 https://reactome.org/PathwayBrowser/#/R-PFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Plasmodium falciparum 29105 R-PFA-1497784 https://reactome.org/PathwayBrowser/#/R-PFA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Plasmodium falciparum 29105 R-PFA-1497796 https://reactome.org/PathwayBrowser/#/R-PFA-1497796 BH2 binding can lead to eNOS uncoupling IEA Plasmodium falciparum 29105 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 29105 R-PFA-189439 https://reactome.org/PathwayBrowser/#/R-PFA-189439 ALAD condenses 2 dALAs to form PBG IEA Plasmodium falciparum 29105 R-PFA-202111 https://reactome.org/PathwayBrowser/#/R-PFA-202111 AKT1 phosphorylates eNOS IEA Plasmodium falciparum 29105 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 29105 R-PFA-202132 https://reactome.org/PathwayBrowser/#/R-PFA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Plasmodium falciparum 29105 R-PFA-203553 https://reactome.org/PathwayBrowser/#/R-PFA-203553 eNOS binds NOSIP IEA Plasmodium falciparum 29105 R-PFA-203680 https://reactome.org/PathwayBrowser/#/R-PFA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Plasmodium falciparum 29105 R-PFA-203700 https://reactome.org/PathwayBrowser/#/R-PFA-203700 eNOS translocation from Golgi to Caveolae IEA Plasmodium falciparum 29105 R-PFA-2730867 https://reactome.org/PathwayBrowser/#/R-PFA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Plasmodium falciparum 29105 R-PFA-2730872 https://reactome.org/PathwayBrowser/#/R-PFA-2730872 Activation of Calcineurin IEA Plasmodium falciparum 29105 R-PFA-435171 https://reactome.org/PathwayBrowser/#/R-PFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Plasmodium falciparum 29105 R-PFA-437136 https://reactome.org/PathwayBrowser/#/R-PFA-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Plasmodium falciparum 29105 R-PFA-437139 https://reactome.org/PathwayBrowser/#/R-PFA-437139 ZnT8 transports zinc into the Golgi apparatus IEA Plasmodium falciparum 29105 R-PFA-442422 https://reactome.org/PathwayBrowser/#/R-PFA-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Plasmodium falciparum 29105 R-PFA-4551465 https://reactome.org/PathwayBrowser/#/R-PFA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Plasmodium falciparum 29105 R-PFA-5688294 https://reactome.org/PathwayBrowser/#/R-PFA-5688294 SIRT5 deacetylates Cytochrome C IEA Plasmodium falciparum 29105 R-PFA-5694071 https://reactome.org/PathwayBrowser/#/R-PFA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Plasmodium falciparum 29105 R-PFA-6783221 https://reactome.org/PathwayBrowser/#/R-PFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Plasmodium falciparum 29105 R-PFA-6788650 https://reactome.org/PathwayBrowser/#/R-PFA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Plasmodium falciparum 29105 R-PFA-8866601 https://reactome.org/PathwayBrowser/#/R-PFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Plasmodium falciparum 29105 R-PFA-947514 https://reactome.org/PathwayBrowser/#/R-PFA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Plasmodium falciparum 29105 R-PFA-964958 https://reactome.org/PathwayBrowser/#/R-PFA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Plasmodium falciparum 29105 R-PFA-964962 https://reactome.org/PathwayBrowser/#/R-PFA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Plasmodium falciparum 29105 R-PFA-964970 https://reactome.org/PathwayBrowser/#/R-PFA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Plasmodium falciparum 29105 R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 29105 R-PFA-9839105 https://reactome.org/PathwayBrowser/#/R-PFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Plasmodium falciparum 29105 R-PFA-9839149 https://reactome.org/PathwayBrowser/#/R-PFA-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Plasmodium falciparum 29105 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 29105 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 29105 R-RNO-1170539 https://reactome.org/PathwayBrowser/#/R-RNO-1170539 Prolactin receptor is internalized IEA Rattus norvegicus 29105 R-RNO-1237045 https://reactome.org/PathwayBrowser/#/R-RNO-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Rattus norvegicus 29105 R-RNO-1237047 https://reactome.org/PathwayBrowser/#/R-RNO-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Rattus norvegicus 29105 R-RNO-1237059 https://reactome.org/PathwayBrowser/#/R-RNO-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Rattus norvegicus 29105 R-RNO-1237081 https://reactome.org/PathwayBrowser/#/R-RNO-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Rattus norvegicus 29105 R-RNO-1369092 https://reactome.org/PathwayBrowser/#/R-RNO-1369092 Prlr binds Shp2 TAS Rattus norvegicus 29105 R-RNO-1369093 https://reactome.org/PathwayBrowser/#/R-RNO-1369093 Prlr binds Stat5 TAS Rattus norvegicus 29105 R-RNO-1369099 https://reactome.org/PathwayBrowser/#/R-RNO-1369099 Shp2 is phosphorylated TAS Rattus norvegicus 29105 R-RNO-1369121 https://reactome.org/PathwayBrowser/#/R-RNO-1369121 Tyrosine phosphorylation of Prlr TAS Rattus norvegicus 29105 R-RNO-1370500 https://reactome.org/PathwayBrowser/#/R-RNO-1370500 PRLR binds SCF beta-TrCP complex IEA Rattus norvegicus 29105 R-RNO-1370505 https://reactome.org/PathwayBrowser/#/R-RNO-1370505 PRLR is phosphorylated at Ser-349 IEA Rattus norvegicus 29105 R-RNO-1474184 https://reactome.org/PathwayBrowser/#/R-RNO-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Rattus norvegicus 29105 R-RNO-1475017 https://reactome.org/PathwayBrowser/#/R-RNO-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Rattus norvegicus 29105 R-RNO-1475022 https://reactome.org/PathwayBrowser/#/R-RNO-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Rattus norvegicus 29105 R-RNO-1475025 https://reactome.org/PathwayBrowser/#/R-RNO-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Rattus norvegicus 29105 R-RNO-1475026 https://reactome.org/PathwayBrowser/#/R-RNO-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Rattus norvegicus 29105 R-RNO-1475028 https://reactome.org/PathwayBrowser/#/R-RNO-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Rattus norvegicus 29105 R-RNO-1475032 https://reactome.org/PathwayBrowser/#/R-RNO-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Rattus norvegicus 29105 R-RNO-1475422 https://reactome.org/PathwayBrowser/#/R-RNO-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Rattus norvegicus 29105 R-RNO-1475435 https://reactome.org/PathwayBrowser/#/R-RNO-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Rattus norvegicus 29105 R-RNO-1475436 https://reactome.org/PathwayBrowser/#/R-RNO-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Rattus norvegicus 29105 R-RNO-1497784 https://reactome.org/PathwayBrowser/#/R-RNO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Rattus norvegicus 29105 R-RNO-1497796 https://reactome.org/PathwayBrowser/#/R-RNO-1497796 BH2 binding can lead to eNOS uncoupling IEA Rattus norvegicus 29105 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 29105 R-RNO-158354 https://reactome.org/PathwayBrowser/#/R-RNO-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer IEA Rattus norvegicus 29105 R-RNO-158941 https://reactome.org/PathwayBrowser/#/R-RNO-158941 plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein IEA Rattus norvegicus 29105 R-RNO-1614605 https://reactome.org/PathwayBrowser/#/R-RNO-1614605 Persulfide sulfur is dioxygenated IEA Rattus norvegicus 29105 R-RNO-1614654 https://reactome.org/PathwayBrowser/#/R-RNO-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Rattus norvegicus 29105 R-RNO-1671687 https://reactome.org/PathwayBrowser/#/R-RNO-1671687 PRLR activation IEA Rattus norvegicus 29105 R-RNO-1671699 https://reactome.org/PathwayBrowser/#/R-RNO-1671699 Prlr-bound Stat5 is phosphorylated TAS Rattus norvegicus 29105 R-RNO-1675473 https://reactome.org/PathwayBrowser/#/R-RNO-1675473 SH2B binds JAK2 IEA Rattus norvegicus 29105 R-RNO-174374 https://reactome.org/PathwayBrowser/#/R-RNO-174374 MTR transfers CH3 from MeCbl to HCYS IEA Rattus norvegicus 29105 R-RNO-182065 https://reactome.org/PathwayBrowser/#/R-RNO-182065 Rap1-GTP binds Raf1 TAS Rattus norvegicus 29105 R-RNO-188339 https://reactome.org/PathwayBrowser/#/R-RNO-188339 Rit-GTP binds Raf TAS Rattus norvegicus 29105 R-RNO-189384 https://reactome.org/PathwayBrowser/#/R-RNO-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Rattus norvegicus 29105 R-RNO-189439 https://reactome.org/PathwayBrowser/#/R-RNO-189439 ALAD condenses 2 dALAs to form PBG IEA Rattus norvegicus 29105 R-RNO-193679 https://reactome.org/PathwayBrowser/#/R-RNO-193679 alpha-secretase cleaves the p75NTR extracellular domain IEA Rattus norvegicus 29105 R-RNO-197198 https://reactome.org/PathwayBrowser/#/R-RNO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 29105 R-RNO-200512 https://reactome.org/PathwayBrowser/#/R-RNO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 29105 R-RNO-201760 https://reactome.org/PathwayBrowser/#/R-RNO-201760 Ppp3 complex dephosphorylates DARPP-32 on T34 TAS Rattus norvegicus 29105 R-RNO-202110 https://reactome.org/PathwayBrowser/#/R-RNO-202110 eNOS:Caveolin-1 complex binds to CaM IEA Rattus norvegicus 29105 R-RNO-202111 https://reactome.org/PathwayBrowser/#/R-RNO-202111 AKT1 phosphorylates eNOS IEA Rattus norvegicus 29105 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 29105 R-RNO-202129 https://reactome.org/PathwayBrowser/#/R-RNO-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Rattus norvegicus 29105 R-RNO-202132 https://reactome.org/PathwayBrowser/#/R-RNO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Rattus norvegicus 29105 R-RNO-202137 https://reactome.org/PathwayBrowser/#/R-RNO-202137 AKT1 binds eNOS complex via HSP90 IEA Rattus norvegicus 29105 R-RNO-202144 https://reactome.org/PathwayBrowser/#/R-RNO-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Rattus norvegicus 29105 R-RNO-2022368 https://reactome.org/PathwayBrowser/#/R-RNO-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Rattus norvegicus 29105 R-RNO-2022378 https://reactome.org/PathwayBrowser/#/R-RNO-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Rattus norvegicus 29105 R-RNO-2022379 https://reactome.org/PathwayBrowser/#/R-RNO-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Rattus norvegicus 29105 R-RNO-2022396 https://reactome.org/PathwayBrowser/#/R-RNO-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Rattus norvegicus 29105 R-RNO-2022398 https://reactome.org/PathwayBrowser/#/R-RNO-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Rattus norvegicus 29105 R-RNO-2022399 https://reactome.org/PathwayBrowser/#/R-RNO-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Rattus norvegicus 29105 R-RNO-2022405 https://reactome.org/PathwayBrowser/#/R-RNO-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 29105 R-RNO-2025890 https://reactome.org/PathwayBrowser/#/R-RNO-2025890 Calcineurin binds NFATC1,2,3 IEA Rattus norvegicus 29105 R-RNO-2028294 https://reactome.org/PathwayBrowser/#/R-RNO-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Rattus norvegicus 29105 R-RNO-203553 https://reactome.org/PathwayBrowser/#/R-RNO-203553 eNOS binds NOSIP IEA Rattus norvegicus 29105 R-RNO-203613 https://reactome.org/PathwayBrowser/#/R-RNO-203613 depalmitoylation of eNOS IEA Rattus norvegicus 29105 R-RNO-203625 https://reactome.org/PathwayBrowser/#/R-RNO-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Rattus norvegicus 29105 R-RNO-203662 https://reactome.org/PathwayBrowser/#/R-RNO-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Rattus norvegicus 29105 R-RNO-203680 https://reactome.org/PathwayBrowser/#/R-RNO-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Rattus norvegicus 29105 R-RNO-203700 https://reactome.org/PathwayBrowser/#/R-RNO-203700 eNOS translocation from Golgi to Caveolae IEA Rattus norvegicus 29105 R-RNO-203712 https://reactome.org/PathwayBrowser/#/R-RNO-203712 eNOS associates with Caveolin-1 IEA Rattus norvegicus 29105 R-RNO-203716 https://reactome.org/PathwayBrowser/#/R-RNO-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Rattus norvegicus 29105 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 29105 R-RNO-2162078 https://reactome.org/PathwayBrowser/#/R-RNO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Rattus norvegicus 29105 R-RNO-264758 https://reactome.org/PathwayBrowser/#/R-RNO-264758 BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 IEA Rattus norvegicus 29105 R-RNO-264976 https://reactome.org/PathwayBrowser/#/R-RNO-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Rattus norvegicus 29105 R-RNO-265153 https://reactome.org/PathwayBrowser/#/R-RNO-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Rattus norvegicus 29105 R-RNO-265682 https://reactome.org/PathwayBrowser/#/R-RNO-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Rattus norvegicus 29105 R-RNO-266012 https://reactome.org/PathwayBrowser/#/R-RNO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Rattus norvegicus 29105 R-RNO-266072 https://reactome.org/PathwayBrowser/#/R-RNO-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Rattus norvegicus 29105 R-RNO-2730849 https://reactome.org/PathwayBrowser/#/R-RNO-2730849 Calcineurin binds and dephosphorylates NFAT IEA Rattus norvegicus 29105 R-RNO-2730867 https://reactome.org/PathwayBrowser/#/R-RNO-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Rattus norvegicus 29105 R-RNO-2730872 https://reactome.org/PathwayBrowser/#/R-RNO-2730872 Activation of Calcineurin IEA Rattus norvegicus 29105 R-RNO-3149518 https://reactome.org/PathwayBrowser/#/R-RNO-3149518 MTRR reduces cob(II)alamin to meCbl IEA Rattus norvegicus 29105 R-RNO-3149539 https://reactome.org/PathwayBrowser/#/R-RNO-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Rattus norvegicus 29105 R-RNO-3204318 https://reactome.org/PathwayBrowser/#/R-RNO-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Rattus norvegicus 29105 R-RNO-3299682 https://reactome.org/PathwayBrowser/#/R-RNO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Rattus norvegicus 29105 R-RNO-3299691 https://reactome.org/PathwayBrowser/#/R-RNO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Rattus norvegicus 29105 R-RNO-3299753 https://reactome.org/PathwayBrowser/#/R-RNO-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Rattus norvegicus 29105 R-RNO-3371385 https://reactome.org/PathwayBrowser/#/R-RNO-3371385 TNF-α is cleaved by ADAM17 (TACE) IEA Rattus norvegicus 29105 R-RNO-3697860 https://reactome.org/PathwayBrowser/#/R-RNO-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Rattus norvegicus 29105 R-RNO-3777112 https://reactome.org/PathwayBrowser/#/R-RNO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Rattus norvegicus 29105 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 29105 R-RNO-428262 https://reactome.org/PathwayBrowser/#/R-RNO-428262 ACER3 hydrolyzes phytoceramide IEA Rattus norvegicus 29105 R-RNO-435171 https://reactome.org/PathwayBrowser/#/R-RNO-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Rattus norvegicus 29105 R-RNO-435366 https://reactome.org/PathwayBrowser/#/R-RNO-435366 ZnT1 mediates the efflux of zinc from the cell IEA Rattus norvegicus 29105 R-RNO-437085 https://reactome.org/PathwayBrowser/#/R-RNO-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Rattus norvegicus 29105 R-RNO-437094 https://reactome.org/PathwayBrowser/#/R-RNO-437094 Znt2 facilitates zinc vesicular sequestration TAS Rattus norvegicus 29105 R-RNO-437136 https://reactome.org/PathwayBrowser/#/R-RNO-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Rattus norvegicus 29105 R-RNO-437139 https://reactome.org/PathwayBrowser/#/R-RNO-437139 ZnT8 transports zinc into the Golgi apparatus IEA Rattus norvegicus 29105 R-RNO-442317 https://reactome.org/PathwayBrowser/#/R-RNO-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Rattus norvegicus 29105 R-RNO-442359 https://reactome.org/PathwayBrowser/#/R-RNO-442359 rZip10 mediates zinc influx into cells TAS Rattus norvegicus 29105 R-RNO-442387 https://reactome.org/PathwayBrowser/#/R-RNO-442387 ZIP8 mediates zinc influx into cells IEA Rattus norvegicus 29105 R-RNO-442422 https://reactome.org/PathwayBrowser/#/R-RNO-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Rattus norvegicus 29105 R-RNO-444572 https://reactome.org/PathwayBrowser/#/R-RNO-444572 Zinc is an agonist of GPR39 IEA Rattus norvegicus 29105 R-RNO-4551451 https://reactome.org/PathwayBrowser/#/R-RNO-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Rattus norvegicus 29105 R-RNO-4551465 https://reactome.org/PathwayBrowser/#/R-RNO-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Rattus norvegicus 29105 R-RNO-4837364 https://reactome.org/PathwayBrowser/#/R-RNO-4837364 Secretion of SOD3 IEA Rattus norvegicus 29105 R-RNO-5362564 https://reactome.org/PathwayBrowser/#/R-RNO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Rattus norvegicus 29105 R-RNO-5433067 https://reactome.org/PathwayBrowser/#/R-RNO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Rattus norvegicus 29105 R-RNO-5433074 https://reactome.org/PathwayBrowser/#/R-RNO-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 29105 R-RNO-5652195 https://reactome.org/PathwayBrowser/#/R-RNO-5652195 SORD oxidizes D-sorbitol to Fru IEA Rattus norvegicus 29105 R-RNO-5661217 https://reactome.org/PathwayBrowser/#/R-RNO-5661217 MT1A binds zinc IEA Rattus norvegicus 29105 R-RNO-5662471 https://reactome.org/PathwayBrowser/#/R-RNO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Rattus norvegicus 29105 R-RNO-5662606 https://reactome.org/PathwayBrowser/#/R-RNO-5662606 MT3 binds zinc IEA Rattus norvegicus 29105 R-RNO-5662613 https://reactome.org/PathwayBrowser/#/R-RNO-5662613 MT3 exchanges zinc for copper IEA Rattus norvegicus 29105 R-RNO-5662660 https://reactome.org/PathwayBrowser/#/R-RNO-5662660 Dopachrome is transformed to DHICA by DCT IEA Rattus norvegicus 29105 R-RNO-5682586 https://reactome.org/PathwayBrowser/#/R-RNO-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Rattus norvegicus 29105 R-RNO-5682588 https://reactome.org/PathwayBrowser/#/R-RNO-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Rattus norvegicus 29105 R-RNO-5682598 https://reactome.org/PathwayBrowser/#/R-RNO-5682598 ATM phosphorylates HERC2 IEA Rattus norvegicus 29105 R-RNO-5682607 https://reactome.org/PathwayBrowser/#/R-RNO-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Rattus norvegicus 29105 R-RNO-5682858 https://reactome.org/PathwayBrowser/#/R-RNO-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Rattus norvegicus 29105 R-RNO-5682863 https://reactome.org/PathwayBrowser/#/R-RNO-5682863 RNF168 binds DNA DSBs IEA Rattus norvegicus 29105 R-RNO-5683077 https://reactome.org/PathwayBrowser/#/R-RNO-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Rattus norvegicus 29105 R-RNO-5683384 https://reactome.org/PathwayBrowser/#/R-RNO-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Rattus norvegicus 29105 R-RNO-5683385 https://reactome.org/PathwayBrowser/#/R-RNO-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Rattus norvegicus 29105 R-RNO-5683405 https://reactome.org/PathwayBrowser/#/R-RNO-5683405 PPP5C dephosphorylates TP53BP1 IEA Rattus norvegicus 29105 R-RNO-5683425 https://reactome.org/PathwayBrowser/#/R-RNO-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Rattus norvegicus 29105 R-RNO-5683735 https://reactome.org/PathwayBrowser/#/R-RNO-5683735 CHEK2 is recruited to DNA DSBs IEA Rattus norvegicus 29105 R-RNO-5683801 https://reactome.org/PathwayBrowser/#/R-RNO-5683801 CHEK2 phosphorylates BRCA1 IEA Rattus norvegicus 29105 R-RNO-5684052 https://reactome.org/PathwayBrowser/#/R-RNO-5684052 PIAS4 SUMOylates MDC1 IEA Rattus norvegicus 29105 R-RNO-5686685 https://reactome.org/PathwayBrowser/#/R-RNO-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Rattus norvegicus 29105 R-RNO-5686704 https://reactome.org/PathwayBrowser/#/R-RNO-5686704 Activated ATM phosphorylates DCLRE1C IEA Rattus norvegicus 29105 R-RNO-5686900 https://reactome.org/PathwayBrowser/#/R-RNO-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Rattus norvegicus 29105 R-RNO-5688276 https://reactome.org/PathwayBrowser/#/R-RNO-5688276 SIRT4 transfers ADPRib to GLUD IEA Rattus norvegicus 29105 R-RNO-5688289 https://reactome.org/PathwayBrowser/#/R-RNO-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Rattus norvegicus 29105 R-RNO-5688294 https://reactome.org/PathwayBrowser/#/R-RNO-5688294 SIRT5 deacetylates Cytochrome C IEA Rattus norvegicus 29105 R-RNO-5691507 https://reactome.org/PathwayBrowser/#/R-RNO-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Rattus norvegicus 29105 R-RNO-5692237 https://reactome.org/PathwayBrowser/#/R-RNO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Rattus norvegicus 29105 R-RNO-5693551 https://reactome.org/PathwayBrowser/#/R-RNO-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Rattus norvegicus 29105 R-RNO-5693566 https://reactome.org/PathwayBrowser/#/R-RNO-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Rattus norvegicus 29105 R-RNO-5694071 https://reactome.org/PathwayBrowser/#/R-RNO-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Rattus norvegicus 29105 R-RNO-5694082 https://reactome.org/PathwayBrowser/#/R-RNO-5694082 XK:KEL:Zn2+ cleaves EDN3 IEA Rattus norvegicus 29105 R-RNO-5696838 https://reactome.org/PathwayBrowser/#/R-RNO-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Rattus norvegicus 29105 R-RNO-6783221 https://reactome.org/PathwayBrowser/#/R-RNO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Rattus norvegicus 29105 R-RNO-6788650 https://reactome.org/PathwayBrowser/#/R-RNO-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Rattus norvegicus 29105 R-RNO-6789072 https://reactome.org/PathwayBrowser/#/R-RNO-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Rattus norvegicus 29105 R-RNO-6798474 https://reactome.org/PathwayBrowser/#/R-RNO-6798474 S100A8:S100A9 binds Zn2+ IEA Rattus norvegicus 29105 R-RNO-6799545 https://reactome.org/PathwayBrowser/#/R-RNO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Rattus norvegicus 29105 R-RNO-6799581 https://reactome.org/PathwayBrowser/#/R-RNO-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Rattus norvegicus 29105 R-RNO-6799959 https://reactome.org/PathwayBrowser/#/R-RNO-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Rattus norvegicus 29105 R-RNO-6799977 https://reactome.org/PathwayBrowser/#/R-RNO-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Rattus norvegicus 29105 R-RNO-69891 https://reactome.org/PathwayBrowser/#/R-RNO-69891 Phosphorylation and activation of CHEK2 by ATM IEA Rattus norvegicus 29105 R-RNO-71707 https://reactome.org/PathwayBrowser/#/R-RNO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Rattus norvegicus 29105 R-RNO-73589 https://reactome.org/PathwayBrowser/#/R-RNO-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Rattus norvegicus 29105 R-RNO-73591 https://reactome.org/PathwayBrowser/#/R-RNO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Rattus norvegicus 29105 R-RNO-73608 https://reactome.org/PathwayBrowser/#/R-RNO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Rattus norvegicus 29105 R-RNO-73618 https://reactome.org/PathwayBrowser/#/R-RNO-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Rattus norvegicus 29105 R-RNO-73620 https://reactome.org/PathwayBrowser/#/R-RNO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Rattus norvegicus 29105 R-RNO-74255 https://reactome.org/PathwayBrowser/#/R-RNO-74255 Guanine + H2O => Xanthine + NH4+ IEA Rattus norvegicus 29105 R-RNO-74730 https://reactome.org/PathwayBrowser/#/R-RNO-74730 Insulin degradation IEA Rattus norvegicus 29105 R-RNO-880007 https://reactome.org/PathwayBrowser/#/R-RNO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Rattus norvegicus 29105 R-RNO-8853686 https://reactome.org/PathwayBrowser/#/R-RNO-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Rattus norvegicus 29105 R-RNO-8866601 https://reactome.org/PathwayBrowser/#/R-RNO-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Rattus norvegicus 29105 R-RNO-8867344 https://reactome.org/PathwayBrowser/#/R-RNO-8867344 OMA1 hydrolyses OPA1 IEA Rattus norvegicus 29105 R-RNO-8878787 https://reactome.org/PathwayBrowser/#/R-RNO-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Rattus norvegicus 29105 R-RNO-8940070 https://reactome.org/PathwayBrowser/#/R-RNO-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Rattus norvegicus 29105 R-RNO-8940074 https://reactome.org/PathwayBrowser/#/R-RNO-8940074 NT5E:Zn2+ hydrolyses NMN IEA Rattus norvegicus 29105 R-RNO-8949649 https://reactome.org/PathwayBrowser/#/R-RNO-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) IEA Rattus norvegicus 29105 R-RNO-8949659 https://reactome.org/PathwayBrowser/#/R-RNO-8949659 AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU IEA Rattus norvegicus 29105 R-RNO-8949661 https://reactome.org/PathwayBrowser/#/R-RNO-8949661 C2orf47:AFG3L2 binds the transit peptide of SMDT1 IEA Rattus norvegicus 29105 R-RNO-8949668 https://reactome.org/PathwayBrowser/#/R-RNO-8949668 YME1L1 proteolyzes unassembled proSMDT1 IEA Rattus norvegicus 29105 R-RNO-8951723 https://reactome.org/PathwayBrowser/#/R-RNO-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Rattus norvegicus 29105 R-RNO-9013284 https://reactome.org/PathwayBrowser/#/R-RNO-9013284 NOTCH3-ligand complex is cleaved to produce NEXT3 IEA Rattus norvegicus 29105 R-RNO-9018862 https://reactome.org/PathwayBrowser/#/R-RNO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Rattus norvegicus 29105 R-RNO-9018877 https://reactome.org/PathwayBrowser/#/R-RNO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Rattus norvegicus 29105 R-RNO-9020252 https://reactome.org/PathwayBrowser/#/R-RNO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Rattus norvegicus 29105 R-RNO-9020253 https://reactome.org/PathwayBrowser/#/R-RNO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Rattus norvegicus 29105 R-RNO-9020257 https://reactome.org/PathwayBrowser/#/R-RNO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Rattus norvegicus 29105 R-RNO-9020258 https://reactome.org/PathwayBrowser/#/R-RNO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Rattus norvegicus 29105 R-RNO-9020270 https://reactome.org/PathwayBrowser/#/R-RNO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Rattus norvegicus 29105 R-RNO-9024890 https://reactome.org/PathwayBrowser/#/R-RNO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Rattus norvegicus 29105 R-RNO-947514 https://reactome.org/PathwayBrowser/#/R-RNO-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Rattus norvegicus 29105 R-RNO-9610152 https://reactome.org/PathwayBrowser/#/R-RNO-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Rattus norvegicus 29105 R-RNO-9610153 https://reactome.org/PathwayBrowser/#/R-RNO-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Rattus norvegicus 29105 R-RNO-9610154 https://reactome.org/PathwayBrowser/#/R-RNO-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Rattus norvegicus 29105 R-RNO-9610156 https://reactome.org/PathwayBrowser/#/R-RNO-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Rattus norvegicus 29105 R-RNO-9610163 https://reactome.org/PathwayBrowser/#/R-RNO-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Rattus norvegicus 29105 R-RNO-9612988 https://reactome.org/PathwayBrowser/#/R-RNO-9612988 Rap1-GTP phosphorylates Raf1 TAS Rattus norvegicus 29105 R-RNO-9638046 https://reactome.org/PathwayBrowser/#/R-RNO-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 29105 R-RNO-9647977 https://reactome.org/PathwayBrowser/#/R-RNO-9647977 ICMT methylates S-Farn RAS proteins IEA Rattus norvegicus 29105 R-RNO-964958 https://reactome.org/PathwayBrowser/#/R-RNO-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Rattus norvegicus 29105 R-RNO-964962 https://reactome.org/PathwayBrowser/#/R-RNO-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Rattus norvegicus 29105 R-RNO-964970 https://reactome.org/PathwayBrowser/#/R-RNO-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Rattus norvegicus 29105 R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 29105 R-RNO-9727607 https://reactome.org/PathwayBrowser/#/R-RNO-9727607 MME:Zn2+ binds sacubitrilat IEA Rattus norvegicus 29105 R-RNO-9753944 https://reactome.org/PathwayBrowser/#/R-RNO-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Rattus norvegicus 29105 R-RNO-975814 https://reactome.org/PathwayBrowser/#/R-RNO-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Rattus norvegicus 29105 R-RNO-976991 https://reactome.org/PathwayBrowser/#/R-RNO-976991 Prolactin receptor ligands bind the prolactin receptor IEA Rattus norvegicus 29105 R-RNO-9820566 https://reactome.org/PathwayBrowser/#/R-RNO-9820566 ZnT5 transports zinc into the golgi apparatus IEA Rattus norvegicus 29105 R-RNO-982810 https://reactome.org/PathwayBrowser/#/R-RNO-982810 JAK2 phosphorylation IEA Rattus norvegicus 29105 R-RNO-9838627 https://reactome.org/PathwayBrowser/#/R-RNO-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Rattus norvegicus 29105 R-RNO-9839053 https://reactome.org/PathwayBrowser/#/R-RNO-9839053 AFG3L2:SPG7 binds SMDT1 (EMRE) IEA Rattus norvegicus 29105 R-RNO-9839059 https://reactome.org/PathwayBrowser/#/R-RNO-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Rattus norvegicus 29105 R-RNO-9839105 https://reactome.org/PathwayBrowser/#/R-RNO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Rattus norvegicus 29105 R-RNO-9839113 https://reactome.org/PathwayBrowser/#/R-RNO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Rattus norvegicus 29105 R-RNO-9839149 https://reactome.org/PathwayBrowser/#/R-RNO-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Rattus norvegicus 29105 R-RNO-9840408 https://reactome.org/PathwayBrowser/#/R-RNO-9840408 OMA1 cleaves DELE1 IEA Rattus norvegicus 29105 R-RNO-9840564 https://reactome.org/PathwayBrowser/#/R-RNO-9840564 OMA1 hydrolyzes YME1L1 IEA Rattus norvegicus 29105 R-RNO-9854463 https://reactome.org/PathwayBrowser/#/R-RNO-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Rattus norvegicus 29105 R-RNO-9861626 https://reactome.org/PathwayBrowser/#/R-RNO-9861626 SIRT4 cleaves lipoyl from DLAT IEA Rattus norvegicus 29105 R-SCE-1237121 https://reactome.org/PathwayBrowser/#/R-SCE-1237121 Dehydration of methylthio-ribulose-P TAS Saccharomyces cerevisiae 29105 R-SCE-1268017 https://reactome.org/PathwayBrowser/#/R-SCE-1268017 MPP hydrolyzes presequence of matrix precursors TAS Saccharomyces cerevisiae 29105 R-SCE-1268019 https://reactome.org/PathwayBrowser/#/R-SCE-1268019 MPP hydrolyzes presequence of inner membrane precursors TAS Saccharomyces cerevisiae 29105 R-SCE-1497784 https://reactome.org/PathwayBrowser/#/R-SCE-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Saccharomyces cerevisiae 29105 R-SCE-1497796 https://reactome.org/PathwayBrowser/#/R-SCE-1497796 BH2 binding can lead to eNOS uncoupling IEA Saccharomyces cerevisiae 29105 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 29105 R-SCE-189439 https://reactome.org/PathwayBrowser/#/R-SCE-189439 ALAD condenses 2 dALAs to form PBG IEA Saccharomyces cerevisiae 29105 R-SCE-197198 https://reactome.org/PathwayBrowser/#/R-SCE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Saccharomyces cerevisiae 29105 R-SCE-200512 https://reactome.org/PathwayBrowser/#/R-SCE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 29105 R-SCE-202111 https://reactome.org/PathwayBrowser/#/R-SCE-202111 AKT1 phosphorylates eNOS IEA Saccharomyces cerevisiae 29105 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 29105 R-SCE-202132 https://reactome.org/PathwayBrowser/#/R-SCE-202132 depalmitoylated eNOS translocates from plasma membrane IEA Saccharomyces cerevisiae 29105 R-SCE-203613 https://reactome.org/PathwayBrowser/#/R-SCE-203613 depalmitoylation of eNOS IEA Saccharomyces cerevisiae 29105 R-SCE-203700 https://reactome.org/PathwayBrowser/#/R-SCE-203700 eNOS translocation from Golgi to Caveolae IEA Saccharomyces cerevisiae 29105 R-SCE-2162078 https://reactome.org/PathwayBrowser/#/R-SCE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Saccharomyces cerevisiae 29105 R-SCE-266072 https://reactome.org/PathwayBrowser/#/R-SCE-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Saccharomyces cerevisiae 29105 R-SCE-3299682 https://reactome.org/PathwayBrowser/#/R-SCE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Saccharomyces cerevisiae 29105 R-SCE-3299691 https://reactome.org/PathwayBrowser/#/R-SCE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Saccharomyces cerevisiae 29105 R-SCE-3299753 https://reactome.org/PathwayBrowser/#/R-SCE-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Saccharomyces cerevisiae 29105 R-SCE-3697860 https://reactome.org/PathwayBrowser/#/R-SCE-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Saccharomyces cerevisiae 29105 R-SCE-3777112 https://reactome.org/PathwayBrowser/#/R-SCE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Saccharomyces cerevisiae 29105 R-SCE-428262 https://reactome.org/PathwayBrowser/#/R-SCE-428262 ACER3 hydrolyzes phytoceramide IEA Saccharomyces cerevisiae 29105 R-SCE-435366 https://reactome.org/PathwayBrowser/#/R-SCE-435366 ZnT1 mediates the efflux of zinc from the cell IEA Saccharomyces cerevisiae 29105 R-SCE-437085 https://reactome.org/PathwayBrowser/#/R-SCE-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Saccharomyces cerevisiae 29105 R-SCE-442393 https://reactome.org/PathwayBrowser/#/R-SCE-442393 ZIP7 mediates zinc efflux from the endoplasmic reticulum IEA Saccharomyces cerevisiae 29105 R-SCE-442422 https://reactome.org/PathwayBrowser/#/R-SCE-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 29105 R-SCE-4837364 https://reactome.org/PathwayBrowser/#/R-SCE-4837364 Secretion of SOD3 IEA Saccharomyces cerevisiae 29105 R-SCE-5362564 https://reactome.org/PathwayBrowser/#/R-SCE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Saccharomyces cerevisiae 29105 R-SCE-5652195 https://reactome.org/PathwayBrowser/#/R-SCE-5652195 SORD oxidizes D-sorbitol to Fru IEA Saccharomyces cerevisiae 29105 R-SCE-5662471 https://reactome.org/PathwayBrowser/#/R-SCE-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Saccharomyces cerevisiae 29105 R-SCE-5682588 https://reactome.org/PathwayBrowser/#/R-SCE-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Saccharomyces cerevisiae 29105 R-SCE-5682598 https://reactome.org/PathwayBrowser/#/R-SCE-5682598 ATM phosphorylates HERC2 IEA Saccharomyces cerevisiae 29105 R-SCE-5682607 https://reactome.org/PathwayBrowser/#/R-SCE-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Saccharomyces cerevisiae 29105 R-SCE-5682629 https://reactome.org/PathwayBrowser/#/R-SCE-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Saccharomyces cerevisiae 29105 R-SCE-5682858 https://reactome.org/PathwayBrowser/#/R-SCE-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Saccharomyces cerevisiae 29105 R-SCE-5683077 https://reactome.org/PathwayBrowser/#/R-SCE-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Saccharomyces cerevisiae 29105 R-SCE-5683405 https://reactome.org/PathwayBrowser/#/R-SCE-5683405 PPP5C dephosphorylates TP53BP1 IEA Saccharomyces cerevisiae 29105 R-SCE-5683425 https://reactome.org/PathwayBrowser/#/R-SCE-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Saccharomyces cerevisiae 29105 R-SCE-5688289 https://reactome.org/PathwayBrowser/#/R-SCE-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Saccharomyces cerevisiae 29105 R-SCE-5692237 https://reactome.org/PathwayBrowser/#/R-SCE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Saccharomyces cerevisiae 29105 R-SCE-5693566 https://reactome.org/PathwayBrowser/#/R-SCE-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Saccharomyces cerevisiae 29105 R-SCE-5694071 https://reactome.org/PathwayBrowser/#/R-SCE-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Saccharomyces cerevisiae 29105 R-SCE-6783221 https://reactome.org/PathwayBrowser/#/R-SCE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Saccharomyces cerevisiae 29105 R-SCE-6788650 https://reactome.org/PathwayBrowser/#/R-SCE-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Saccharomyces cerevisiae 29105 R-SCE-6799545 https://reactome.org/PathwayBrowser/#/R-SCE-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Saccharomyces cerevisiae 29105 R-SCE-71707 https://reactome.org/PathwayBrowser/#/R-SCE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Saccharomyces cerevisiae 29105 R-SCE-73608 https://reactome.org/PathwayBrowser/#/R-SCE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Saccharomyces cerevisiae 29105 R-SCE-74255 https://reactome.org/PathwayBrowser/#/R-SCE-74255 Guanine + H2O => Xanthine + NH4+ IEA Saccharomyces cerevisiae 29105 R-SCE-880007 https://reactome.org/PathwayBrowser/#/R-SCE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Saccharomyces cerevisiae 29105 R-SCE-8867344 https://reactome.org/PathwayBrowser/#/R-SCE-8867344 OMA1 hydrolyses OPA1 IEA Saccharomyces cerevisiae 29105 R-SCE-8951723 https://reactome.org/PathwayBrowser/#/R-SCE-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Saccharomyces cerevisiae 29105 R-SCE-9018862 https://reactome.org/PathwayBrowser/#/R-SCE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Saccharomyces cerevisiae 29105 R-SCE-9018877 https://reactome.org/PathwayBrowser/#/R-SCE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Saccharomyces cerevisiae 29105 R-SCE-9020252 https://reactome.org/PathwayBrowser/#/R-SCE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Saccharomyces cerevisiae 29105 R-SCE-9020253 https://reactome.org/PathwayBrowser/#/R-SCE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Saccharomyces cerevisiae 29105 R-SCE-9020257 https://reactome.org/PathwayBrowser/#/R-SCE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Saccharomyces cerevisiae 29105 R-SCE-9020258 https://reactome.org/PathwayBrowser/#/R-SCE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Saccharomyces cerevisiae 29105 R-SCE-9020270 https://reactome.org/PathwayBrowser/#/R-SCE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Saccharomyces cerevisiae 29105 R-SCE-9024890 https://reactome.org/PathwayBrowser/#/R-SCE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Saccharomyces cerevisiae 29105 R-SCE-947514 https://reactome.org/PathwayBrowser/#/R-SCE-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Saccharomyces cerevisiae 29105 R-SCE-964958 https://reactome.org/PathwayBrowser/#/R-SCE-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Saccharomyces cerevisiae 29105 R-SCE-964962 https://reactome.org/PathwayBrowser/#/R-SCE-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Saccharomyces cerevisiae 29105 R-SCE-964970 https://reactome.org/PathwayBrowser/#/R-SCE-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Saccharomyces cerevisiae 29105 R-SCE-9820566 https://reactome.org/PathwayBrowser/#/R-SCE-9820566 ZnT5 transports zinc into the golgi apparatus IEA Saccharomyces cerevisiae 29105 R-SCE-9838627 https://reactome.org/PathwayBrowser/#/R-SCE-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 29105 R-SCE-9839105 https://reactome.org/PathwayBrowser/#/R-SCE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Saccharomyces cerevisiae 29105 R-SCE-9839113 https://reactome.org/PathwayBrowser/#/R-SCE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 29105 R-SCE-9839149 https://reactome.org/PathwayBrowser/#/R-SCE-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Saccharomyces cerevisiae 29105 R-SCE-9839836 https://reactome.org/PathwayBrowser/#/R-SCE-9839836 YME1 degrades TIM10 TAS Saccharomyces cerevisiae 29105 R-SCE-9839844 https://reactome.org/PathwayBrowser/#/R-SCE-9839844 YME1 binds COX2 TAS Saccharomyces cerevisiae 29105 R-SCE-9840564 https://reactome.org/PathwayBrowser/#/R-SCE-9840564 OMA1 hydrolyzes YME1L1 IEA Saccharomyces cerevisiae 29105 R-SPO-1497784 https://reactome.org/PathwayBrowser/#/R-SPO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Schizosaccharomyces pombe 29105 R-SPO-1497796 https://reactome.org/PathwayBrowser/#/R-SPO-1497796 BH2 binding can lead to eNOS uncoupling IEA Schizosaccharomyces pombe 29105 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 29105 R-SPO-189439 https://reactome.org/PathwayBrowser/#/R-SPO-189439 ALAD condenses 2 dALAs to form PBG IEA Schizosaccharomyces pombe 29105 R-SPO-197198 https://reactome.org/PathwayBrowser/#/R-SPO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Schizosaccharomyces pombe 29105 R-SPO-200512 https://reactome.org/PathwayBrowser/#/R-SPO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 29105 R-SPO-202111 https://reactome.org/PathwayBrowser/#/R-SPO-202111 AKT1 phosphorylates eNOS IEA Schizosaccharomyces pombe 29105 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 29105 R-SPO-202132 https://reactome.org/PathwayBrowser/#/R-SPO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Schizosaccharomyces pombe 29105 R-SPO-202137 https://reactome.org/PathwayBrowser/#/R-SPO-202137 AKT1 binds eNOS complex via HSP90 IEA Schizosaccharomyces pombe 29105 R-SPO-203613 https://reactome.org/PathwayBrowser/#/R-SPO-203613 depalmitoylation of eNOS IEA Schizosaccharomyces pombe 29105 R-SPO-203700 https://reactome.org/PathwayBrowser/#/R-SPO-203700 eNOS translocation from Golgi to Caveolae IEA Schizosaccharomyces pombe 29105 R-SPO-2162078 https://reactome.org/PathwayBrowser/#/R-SPO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Schizosaccharomyces pombe 29105 R-SPO-266012 https://reactome.org/PathwayBrowser/#/R-SPO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Schizosaccharomyces pombe 29105 R-SPO-266072 https://reactome.org/PathwayBrowser/#/R-SPO-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Schizosaccharomyces pombe 29105 R-SPO-2730867 https://reactome.org/PathwayBrowser/#/R-SPO-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Schizosaccharomyces pombe 29105 R-SPO-2730872 https://reactome.org/PathwayBrowser/#/R-SPO-2730872 Activation of Calcineurin IEA Schizosaccharomyces pombe 29105 R-SPO-3299682 https://reactome.org/PathwayBrowser/#/R-SPO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Schizosaccharomyces pombe 29105 R-SPO-3299691 https://reactome.org/PathwayBrowser/#/R-SPO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Schizosaccharomyces pombe 29105 R-SPO-3777112 https://reactome.org/PathwayBrowser/#/R-SPO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Schizosaccharomyces pombe 29105 R-SPO-435366 https://reactome.org/PathwayBrowser/#/R-SPO-435366 ZnT1 mediates the efflux of zinc from the cell IEA Schizosaccharomyces pombe 29105 R-SPO-437085 https://reactome.org/PathwayBrowser/#/R-SPO-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Schizosaccharomyces pombe 29105 R-SPO-442393 https://reactome.org/PathwayBrowser/#/R-SPO-442393 ZIP7 mediates zinc efflux from the endoplasmic reticulum IEA Schizosaccharomyces pombe 29105 R-SPO-4551465 https://reactome.org/PathwayBrowser/#/R-SPO-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Schizosaccharomyces pombe 29105 R-SPO-4837364 https://reactome.org/PathwayBrowser/#/R-SPO-4837364 Secretion of SOD3 IEA Schizosaccharomyces pombe 29105 R-SPO-5362564 https://reactome.org/PathwayBrowser/#/R-SPO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Schizosaccharomyces pombe 29105 R-SPO-5433067 https://reactome.org/PathwayBrowser/#/R-SPO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Schizosaccharomyces pombe 29105 R-SPO-5652195 https://reactome.org/PathwayBrowser/#/R-SPO-5652195 SORD oxidizes D-sorbitol to Fru IEA Schizosaccharomyces pombe 29105 R-SPO-5662471 https://reactome.org/PathwayBrowser/#/R-SPO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Schizosaccharomyces pombe 29105 R-SPO-5682588 https://reactome.org/PathwayBrowser/#/R-SPO-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Schizosaccharomyces pombe 29105 R-SPO-5682598 https://reactome.org/PathwayBrowser/#/R-SPO-5682598 ATM phosphorylates HERC2 IEA Schizosaccharomyces pombe 29105 R-SPO-5682607 https://reactome.org/PathwayBrowser/#/R-SPO-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Schizosaccharomyces pombe 29105 R-SPO-5682629 https://reactome.org/PathwayBrowser/#/R-SPO-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Schizosaccharomyces pombe 29105 R-SPO-5682858 https://reactome.org/PathwayBrowser/#/R-SPO-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Schizosaccharomyces pombe 29105 R-SPO-5683405 https://reactome.org/PathwayBrowser/#/R-SPO-5683405 PPP5C dephosphorylates TP53BP1 IEA Schizosaccharomyces pombe 29105 R-SPO-5683425 https://reactome.org/PathwayBrowser/#/R-SPO-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Schizosaccharomyces pombe 29105 R-SPO-5688289 https://reactome.org/PathwayBrowser/#/R-SPO-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Schizosaccharomyces pombe 29105 R-SPO-5692237 https://reactome.org/PathwayBrowser/#/R-SPO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Schizosaccharomyces pombe 29105 R-SPO-5693566 https://reactome.org/PathwayBrowser/#/R-SPO-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Schizosaccharomyces pombe 29105 R-SPO-5694071 https://reactome.org/PathwayBrowser/#/R-SPO-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Schizosaccharomyces pombe 29105 R-SPO-6783221 https://reactome.org/PathwayBrowser/#/R-SPO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Schizosaccharomyces pombe 29105 R-SPO-6788650 https://reactome.org/PathwayBrowser/#/R-SPO-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Schizosaccharomyces pombe 29105 R-SPO-6799545 https://reactome.org/PathwayBrowser/#/R-SPO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Schizosaccharomyces pombe 29105 R-SPO-71707 https://reactome.org/PathwayBrowser/#/R-SPO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Schizosaccharomyces pombe 29105 R-SPO-73591 https://reactome.org/PathwayBrowser/#/R-SPO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Schizosaccharomyces pombe 29105 R-SPO-73608 https://reactome.org/PathwayBrowser/#/R-SPO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Schizosaccharomyces pombe 29105 R-SPO-73620 https://reactome.org/PathwayBrowser/#/R-SPO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Schizosaccharomyces pombe 29105 R-SPO-74255 https://reactome.org/PathwayBrowser/#/R-SPO-74255 Guanine + H2O => Xanthine + NH4+ IEA Schizosaccharomyces pombe 29105 R-SPO-880007 https://reactome.org/PathwayBrowser/#/R-SPO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Schizosaccharomyces pombe 29105 R-SPO-8867344 https://reactome.org/PathwayBrowser/#/R-SPO-8867344 OMA1 hydrolyses OPA1 IEA Schizosaccharomyces pombe 29105 R-SPO-9018862 https://reactome.org/PathwayBrowser/#/R-SPO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Schizosaccharomyces pombe 29105 R-SPO-9018877 https://reactome.org/PathwayBrowser/#/R-SPO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Schizosaccharomyces pombe 29105 R-SPO-9020252 https://reactome.org/PathwayBrowser/#/R-SPO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Schizosaccharomyces pombe 29105 R-SPO-9020253 https://reactome.org/PathwayBrowser/#/R-SPO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Schizosaccharomyces pombe 29105 R-SPO-9020257 https://reactome.org/PathwayBrowser/#/R-SPO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Schizosaccharomyces pombe 29105 R-SPO-9020258 https://reactome.org/PathwayBrowser/#/R-SPO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Schizosaccharomyces pombe 29105 R-SPO-9020270 https://reactome.org/PathwayBrowser/#/R-SPO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Schizosaccharomyces pombe 29105 R-SPO-9024890 https://reactome.org/PathwayBrowser/#/R-SPO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Schizosaccharomyces pombe 29105 R-SPO-947514 https://reactome.org/PathwayBrowser/#/R-SPO-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Schizosaccharomyces pombe 29105 R-SPO-964958 https://reactome.org/PathwayBrowser/#/R-SPO-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Schizosaccharomyces pombe 29105 R-SPO-964962 https://reactome.org/PathwayBrowser/#/R-SPO-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Schizosaccharomyces pombe 29105 R-SPO-964970 https://reactome.org/PathwayBrowser/#/R-SPO-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Schizosaccharomyces pombe 29105 R-SPO-9820566 https://reactome.org/PathwayBrowser/#/R-SPO-9820566 ZnT5 transports zinc into the golgi apparatus IEA Schizosaccharomyces pombe 29105 R-SPO-9838627 https://reactome.org/PathwayBrowser/#/R-SPO-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 29105 R-SPO-9839105 https://reactome.org/PathwayBrowser/#/R-SPO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Schizosaccharomyces pombe 29105 R-SPO-9839113 https://reactome.org/PathwayBrowser/#/R-SPO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 29105 R-SPO-9839149 https://reactome.org/PathwayBrowser/#/R-SPO-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Schizosaccharomyces pombe 29105 R-SPO-9840564 https://reactome.org/PathwayBrowser/#/R-SPO-9840564 OMA1 hydrolyzes YME1L1 IEA Schizosaccharomyces pombe 29105 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 29105 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 29105 R-SSC-1170539 https://reactome.org/PathwayBrowser/#/R-SSC-1170539 Prolactin receptor is internalized IEA Sus scrofa 29105 R-SSC-1237045 https://reactome.org/PathwayBrowser/#/R-SSC-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Sus scrofa 29105 R-SSC-1237047 https://reactome.org/PathwayBrowser/#/R-SSC-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Sus scrofa 29105 R-SSC-1237059 https://reactome.org/PathwayBrowser/#/R-SSC-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Sus scrofa 29105 R-SSC-1237081 https://reactome.org/PathwayBrowser/#/R-SSC-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Sus scrofa 29105 R-SSC-1370500 https://reactome.org/PathwayBrowser/#/R-SSC-1370500 PRLR binds SCF beta-TrCP complex IEA Sus scrofa 29105 R-SSC-1370505 https://reactome.org/PathwayBrowser/#/R-SSC-1370505 PRLR is phosphorylated at Ser-349 IEA Sus scrofa 29105 R-SSC-1474184 https://reactome.org/PathwayBrowser/#/R-SSC-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Sus scrofa 29105 R-SSC-1475017 https://reactome.org/PathwayBrowser/#/R-SSC-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Sus scrofa 29105 R-SSC-1475022 https://reactome.org/PathwayBrowser/#/R-SSC-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Sus scrofa 29105 R-SSC-1475025 https://reactome.org/PathwayBrowser/#/R-SSC-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Sus scrofa 29105 R-SSC-1475026 https://reactome.org/PathwayBrowser/#/R-SSC-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Sus scrofa 29105 R-SSC-1475028 https://reactome.org/PathwayBrowser/#/R-SSC-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Sus scrofa 29105 R-SSC-1475032 https://reactome.org/PathwayBrowser/#/R-SSC-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Sus scrofa 29105 R-SSC-1475422 https://reactome.org/PathwayBrowser/#/R-SSC-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Sus scrofa 29105 R-SSC-1475435 https://reactome.org/PathwayBrowser/#/R-SSC-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Sus scrofa 29105 R-SSC-1475436 https://reactome.org/PathwayBrowser/#/R-SSC-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Sus scrofa 29105 R-SSC-1497784 https://reactome.org/PathwayBrowser/#/R-SSC-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Sus scrofa 29105 R-SSC-1497796 https://reactome.org/PathwayBrowser/#/R-SSC-1497796 BH2 binding can lead to eNOS uncoupling IEA Sus scrofa 29105 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 29105 R-SSC-158354 https://reactome.org/PathwayBrowser/#/R-SSC-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer IEA Sus scrofa 29105 R-SSC-158941 https://reactome.org/PathwayBrowser/#/R-SSC-158941 plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein IEA Sus scrofa 29105 R-SSC-1614605 https://reactome.org/PathwayBrowser/#/R-SSC-1614605 Persulfide sulfur is dioxygenated IEA Sus scrofa 29105 R-SSC-1614654 https://reactome.org/PathwayBrowser/#/R-SSC-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Sus scrofa 29105 R-SSC-1671687 https://reactome.org/PathwayBrowser/#/R-SSC-1671687 PRLR activation IEA Sus scrofa 29105 R-SSC-1675473 https://reactome.org/PathwayBrowser/#/R-SSC-1675473 SH2B binds JAK2 IEA Sus scrofa 29105 R-SSC-174374 https://reactome.org/PathwayBrowser/#/R-SSC-174374 MTR transfers CH3 from MeCbl to HCYS IEA Sus scrofa 29105 R-SSC-189384 https://reactome.org/PathwayBrowser/#/R-SSC-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Sus scrofa 29105 R-SSC-189439 https://reactome.org/PathwayBrowser/#/R-SSC-189439 ALAD condenses 2 dALAs to form PBG IEA Sus scrofa 29105 R-SSC-193679 https://reactome.org/PathwayBrowser/#/R-SSC-193679 alpha-secretase cleaves the p75NTR extracellular domain IEA Sus scrofa 29105 R-SSC-197198 https://reactome.org/PathwayBrowser/#/R-SSC-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Sus scrofa 29105 R-SSC-200512 https://reactome.org/PathwayBrowser/#/R-SSC-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 29105 R-SSC-202110 https://reactome.org/PathwayBrowser/#/R-SSC-202110 eNOS:Caveolin-1 complex binds to CaM IEA Sus scrofa 29105 R-SSC-202111 https://reactome.org/PathwayBrowser/#/R-SSC-202111 AKT1 phosphorylates eNOS IEA Sus scrofa 29105 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 29105 R-SSC-202129 https://reactome.org/PathwayBrowser/#/R-SSC-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Sus scrofa 29105 R-SSC-202132 https://reactome.org/PathwayBrowser/#/R-SSC-202132 depalmitoylated eNOS translocates from plasma membrane IEA Sus scrofa 29105 R-SSC-202144 https://reactome.org/PathwayBrowser/#/R-SSC-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Sus scrofa 29105 R-SSC-2022368 https://reactome.org/PathwayBrowser/#/R-SSC-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Sus scrofa 29105 R-SSC-2022378 https://reactome.org/PathwayBrowser/#/R-SSC-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Sus scrofa 29105 R-SSC-2022379 https://reactome.org/PathwayBrowser/#/R-SSC-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Sus scrofa 29105 R-SSC-2022396 https://reactome.org/PathwayBrowser/#/R-SSC-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Sus scrofa 29105 R-SSC-2022398 https://reactome.org/PathwayBrowser/#/R-SSC-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Sus scrofa 29105 R-SSC-2022399 https://reactome.org/PathwayBrowser/#/R-SSC-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Sus scrofa 29105 R-SSC-2022405 https://reactome.org/PathwayBrowser/#/R-SSC-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 29105 R-SSC-2025890 https://reactome.org/PathwayBrowser/#/R-SSC-2025890 Calcineurin binds NFATC1,2,3 IEA Sus scrofa 29105 R-SSC-203553 https://reactome.org/PathwayBrowser/#/R-SSC-203553 eNOS binds NOSIP IEA Sus scrofa 29105 R-SSC-203565 https://reactome.org/PathwayBrowser/#/R-SSC-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Sus scrofa 29105 R-SSC-203613 https://reactome.org/PathwayBrowser/#/R-SSC-203613 depalmitoylation of eNOS IEA Sus scrofa 29105 R-SSC-203625 https://reactome.org/PathwayBrowser/#/R-SSC-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Sus scrofa 29105 R-SSC-203662 https://reactome.org/PathwayBrowser/#/R-SSC-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Sus scrofa 29105 R-SSC-203680 https://reactome.org/PathwayBrowser/#/R-SSC-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Sus scrofa 29105 R-SSC-203700 https://reactome.org/PathwayBrowser/#/R-SSC-203700 eNOS translocation from Golgi to Caveolae IEA Sus scrofa 29105 R-SSC-203712 https://reactome.org/PathwayBrowser/#/R-SSC-203712 eNOS associates with Caveolin-1 IEA Sus scrofa 29105 R-SSC-203716 https://reactome.org/PathwayBrowser/#/R-SSC-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Sus scrofa 29105 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 29105 R-SSC-2161187 https://reactome.org/PathwayBrowser/#/R-SSC-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Sus scrofa 29105 R-SSC-2161195 https://reactome.org/PathwayBrowser/#/R-SSC-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Sus scrofa 29105 R-SSC-2162078 https://reactome.org/PathwayBrowser/#/R-SSC-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Sus scrofa 29105 R-SSC-264758 https://reactome.org/PathwayBrowser/#/R-SSC-264758 BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 IEA Sus scrofa 29105 R-SSC-264976 https://reactome.org/PathwayBrowser/#/R-SSC-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Sus scrofa 29105 R-SSC-265153 https://reactome.org/PathwayBrowser/#/R-SSC-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Sus scrofa 29105 R-SSC-265682 https://reactome.org/PathwayBrowser/#/R-SSC-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Sus scrofa 29105 R-SSC-266012 https://reactome.org/PathwayBrowser/#/R-SSC-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Sus scrofa 29105 R-SSC-266072 https://reactome.org/PathwayBrowser/#/R-SSC-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Sus scrofa 29105 R-SSC-2730849 https://reactome.org/PathwayBrowser/#/R-SSC-2730849 Calcineurin binds and dephosphorylates NFAT IEA Sus scrofa 29105 R-SSC-2730867 https://reactome.org/PathwayBrowser/#/R-SSC-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Sus scrofa 29105 R-SSC-2730872 https://reactome.org/PathwayBrowser/#/R-SSC-2730872 Activation of Calcineurin IEA Sus scrofa 29105 R-SSC-3149518 https://reactome.org/PathwayBrowser/#/R-SSC-3149518 MTRR reduces cob(II)alamin to meCbl IEA Sus scrofa 29105 R-SSC-3149539 https://reactome.org/PathwayBrowser/#/R-SSC-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Sus scrofa 29105 R-SSC-3204318 https://reactome.org/PathwayBrowser/#/R-SSC-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Sus scrofa 29105 R-SSC-3299682 https://reactome.org/PathwayBrowser/#/R-SSC-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Sus scrofa 29105 R-SSC-3299691 https://reactome.org/PathwayBrowser/#/R-SSC-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Sus scrofa 29105 R-SSC-3299753 https://reactome.org/PathwayBrowser/#/R-SSC-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Sus scrofa 29105 R-SSC-3371385 https://reactome.org/PathwayBrowser/#/R-SSC-3371385 TNF-α is cleaved by ADAM17 (TACE) IEA Sus scrofa 29105 R-SSC-3697860 https://reactome.org/PathwayBrowser/#/R-SSC-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Sus scrofa 29105 R-SSC-3777112 https://reactome.org/PathwayBrowser/#/R-SSC-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Sus scrofa 29105 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 29105 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 29105 R-SSC-428262 https://reactome.org/PathwayBrowser/#/R-SSC-428262 ACER3 hydrolyzes phytoceramide IEA Sus scrofa 29105 R-SSC-435171 https://reactome.org/PathwayBrowser/#/R-SSC-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Sus scrofa 29105 R-SSC-435366 https://reactome.org/PathwayBrowser/#/R-SSC-435366 ZnT1 mediates the efflux of zinc from the cell IEA Sus scrofa 29105 R-SSC-437085 https://reactome.org/PathwayBrowser/#/R-SSC-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Sus scrofa 29105 R-SSC-437136 https://reactome.org/PathwayBrowser/#/R-SSC-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Sus scrofa 29105 R-SSC-437139 https://reactome.org/PathwayBrowser/#/R-SSC-437139 ZnT8 transports zinc into the Golgi apparatus IEA Sus scrofa 29105 R-SSC-442317 https://reactome.org/PathwayBrowser/#/R-SSC-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Sus scrofa 29105 R-SSC-442387 https://reactome.org/PathwayBrowser/#/R-SSC-442387 ZIP8 mediates zinc influx into cells IEA Sus scrofa 29105 R-SSC-442393 https://reactome.org/PathwayBrowser/#/R-SSC-442393 ZIP7 mediates zinc efflux from the endoplasmic reticulum IEA Sus scrofa 29105 R-SSC-442422 https://reactome.org/PathwayBrowser/#/R-SSC-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Sus scrofa 29105 R-SSC-444572 https://reactome.org/PathwayBrowser/#/R-SSC-444572 Zinc is an agonist of GPR39 IEA Sus scrofa 29105 R-SSC-4551451 https://reactome.org/PathwayBrowser/#/R-SSC-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Sus scrofa 29105 R-SSC-4551465 https://reactome.org/PathwayBrowser/#/R-SSC-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Sus scrofa 29105 R-SSC-4837364 https://reactome.org/PathwayBrowser/#/R-SSC-4837364 Secretion of SOD3 IEA Sus scrofa 29105 R-SSC-5362564 https://reactome.org/PathwayBrowser/#/R-SSC-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Sus scrofa 29105 R-SSC-5433067 https://reactome.org/PathwayBrowser/#/R-SSC-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Sus scrofa 29105 R-SSC-5433074 https://reactome.org/PathwayBrowser/#/R-SSC-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Sus scrofa 29105 R-SSC-5652195 https://reactome.org/PathwayBrowser/#/R-SSC-5652195 SORD oxidizes D-sorbitol to Fru IEA Sus scrofa 29105 R-SSC-5661217 https://reactome.org/PathwayBrowser/#/R-SSC-5661217 MT1A binds zinc IEA Sus scrofa 29105 R-SSC-5662471 https://reactome.org/PathwayBrowser/#/R-SSC-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Sus scrofa 29105 R-SSC-5662606 https://reactome.org/PathwayBrowser/#/R-SSC-5662606 MT3 binds zinc IEA Sus scrofa 29105 R-SSC-5662613 https://reactome.org/PathwayBrowser/#/R-SSC-5662613 MT3 exchanges zinc for copper IEA Sus scrofa 29105 R-SSC-5662660 https://reactome.org/PathwayBrowser/#/R-SSC-5662660 Dopachrome is transformed to DHICA by DCT IEA Sus scrofa 29105 R-SSC-5682586 https://reactome.org/PathwayBrowser/#/R-SSC-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Sus scrofa 29105 R-SSC-5682588 https://reactome.org/PathwayBrowser/#/R-SSC-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Sus scrofa 29105 R-SSC-5682598 https://reactome.org/PathwayBrowser/#/R-SSC-5682598 ATM phosphorylates HERC2 IEA Sus scrofa 29105 R-SSC-5682607 https://reactome.org/PathwayBrowser/#/R-SSC-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Sus scrofa 29105 R-SSC-5682858 https://reactome.org/PathwayBrowser/#/R-SSC-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Sus scrofa 29105 R-SSC-5682863 https://reactome.org/PathwayBrowser/#/R-SSC-5682863 RNF168 binds DNA DSBs IEA Sus scrofa 29105 R-SSC-5683077 https://reactome.org/PathwayBrowser/#/R-SSC-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Sus scrofa 29105 R-SSC-5683384 https://reactome.org/PathwayBrowser/#/R-SSC-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Sus scrofa 29105 R-SSC-5683385 https://reactome.org/PathwayBrowser/#/R-SSC-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Sus scrofa 29105 R-SSC-5683405 https://reactome.org/PathwayBrowser/#/R-SSC-5683405 PPP5C dephosphorylates TP53BP1 IEA Sus scrofa 29105 R-SSC-5683425 https://reactome.org/PathwayBrowser/#/R-SSC-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Sus scrofa 29105 R-SSC-5683735 https://reactome.org/PathwayBrowser/#/R-SSC-5683735 CHEK2 is recruited to DNA DSBs IEA Sus scrofa 29105 R-SSC-5683801 https://reactome.org/PathwayBrowser/#/R-SSC-5683801 CHEK2 phosphorylates BRCA1 IEA Sus scrofa 29105 R-SSC-5684052 https://reactome.org/PathwayBrowser/#/R-SSC-5684052 PIAS4 SUMOylates MDC1 IEA Sus scrofa 29105 R-SSC-5686685 https://reactome.org/PathwayBrowser/#/R-SSC-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Sus scrofa 29105 R-SSC-5686704 https://reactome.org/PathwayBrowser/#/R-SSC-5686704 Activated ATM phosphorylates DCLRE1C IEA Sus scrofa 29105 R-SSC-5686900 https://reactome.org/PathwayBrowser/#/R-SSC-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Sus scrofa 29105 R-SSC-5688276 https://reactome.org/PathwayBrowser/#/R-SSC-5688276 SIRT4 transfers ADPRib to GLUD IEA Sus scrofa 29105 R-SSC-5688289 https://reactome.org/PathwayBrowser/#/R-SSC-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Sus scrofa 29105 R-SSC-5688294 https://reactome.org/PathwayBrowser/#/R-SSC-5688294 SIRT5 deacetylates Cytochrome C IEA Sus scrofa 29105 R-SSC-5691507 https://reactome.org/PathwayBrowser/#/R-SSC-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Sus scrofa 29105 R-SSC-5692237 https://reactome.org/PathwayBrowser/#/R-SSC-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Sus scrofa 29105 R-SSC-5693346 https://reactome.org/PathwayBrowser/#/R-SSC-5693346 CECRI deaminates Ade-Rib to Ino IEA Sus scrofa 29105 R-SSC-5693551 https://reactome.org/PathwayBrowser/#/R-SSC-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Sus scrofa 29105 R-SSC-5693566 https://reactome.org/PathwayBrowser/#/R-SSC-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Sus scrofa 29105 R-SSC-5694071 https://reactome.org/PathwayBrowser/#/R-SSC-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Sus scrofa 29105 R-SSC-5694082 https://reactome.org/PathwayBrowser/#/R-SSC-5694082 XK:KEL:Zn2+ cleaves EDN3 IEA Sus scrofa 29105 R-SSC-5696838 https://reactome.org/PathwayBrowser/#/R-SSC-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Sus scrofa 29105 R-SSC-6783221 https://reactome.org/PathwayBrowser/#/R-SSC-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Sus scrofa 29105 R-SSC-6789072 https://reactome.org/PathwayBrowser/#/R-SSC-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Sus scrofa 29105 R-SSC-6798474 https://reactome.org/PathwayBrowser/#/R-SSC-6798474 S100A8:S100A9 binds Zn2+ IEA Sus scrofa 29105 R-SSC-6798489 https://reactome.org/PathwayBrowser/#/R-SSC-6798489 S100A7 or S100A7A binds Zn2+ IEA Sus scrofa 29105 R-SSC-6799545 https://reactome.org/PathwayBrowser/#/R-SSC-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Sus scrofa 29105 R-SSC-6799581 https://reactome.org/PathwayBrowser/#/R-SSC-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Sus scrofa 29105 R-SSC-6799959 https://reactome.org/PathwayBrowser/#/R-SSC-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Sus scrofa 29105 R-SSC-6799977 https://reactome.org/PathwayBrowser/#/R-SSC-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Sus scrofa 29105 R-SSC-69891 https://reactome.org/PathwayBrowser/#/R-SSC-69891 Phosphorylation and activation of CHEK2 by ATM IEA Sus scrofa 29105 R-SSC-71707 https://reactome.org/PathwayBrowser/#/R-SSC-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Sus scrofa 29105 R-SSC-73589 https://reactome.org/PathwayBrowser/#/R-SSC-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Sus scrofa 29105 R-SSC-73591 https://reactome.org/PathwayBrowser/#/R-SSC-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Sus scrofa 29105 R-SSC-73608 https://reactome.org/PathwayBrowser/#/R-SSC-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Sus scrofa 29105 R-SSC-73618 https://reactome.org/PathwayBrowser/#/R-SSC-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Sus scrofa 29105 R-SSC-73620 https://reactome.org/PathwayBrowser/#/R-SSC-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Sus scrofa 29105 R-SSC-74255 https://reactome.org/PathwayBrowser/#/R-SSC-74255 Guanine + H2O => Xanthine + NH4+ IEA Sus scrofa 29105 R-SSC-74730 https://reactome.org/PathwayBrowser/#/R-SSC-74730 Insulin degradation IEA Sus scrofa 29105 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 29105 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 29105 R-SSC-880007 https://reactome.org/PathwayBrowser/#/R-SSC-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa 29105 R-SSC-8853686 https://reactome.org/PathwayBrowser/#/R-SSC-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Sus scrofa 29105 R-SSC-8866601 https://reactome.org/PathwayBrowser/#/R-SSC-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Sus scrofa 29105 R-SSC-8867344 https://reactome.org/PathwayBrowser/#/R-SSC-8867344 OMA1 hydrolyses OPA1 IEA Sus scrofa 29105 R-SSC-8878787 https://reactome.org/PathwayBrowser/#/R-SSC-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Sus scrofa 29105 R-SSC-8940070 https://reactome.org/PathwayBrowser/#/R-SSC-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Sus scrofa 29105 R-SSC-8940074 https://reactome.org/PathwayBrowser/#/R-SSC-8940074 NT5E:Zn2+ hydrolyses NMN IEA Sus scrofa 29105 R-SSC-8949649 https://reactome.org/PathwayBrowser/#/R-SSC-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) IEA Sus scrofa 29105 R-SSC-8949659 https://reactome.org/PathwayBrowser/#/R-SSC-8949659 AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU IEA Sus scrofa 29105 R-SSC-8949661 https://reactome.org/PathwayBrowser/#/R-SSC-8949661 C2orf47:AFG3L2 binds the transit peptide of SMDT1 IEA Sus scrofa 29105 R-SSC-8951723 https://reactome.org/PathwayBrowser/#/R-SSC-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Sus scrofa 29105 R-SSC-9018862 https://reactome.org/PathwayBrowser/#/R-SSC-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Sus scrofa 29105 R-SSC-9018877 https://reactome.org/PathwayBrowser/#/R-SSC-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Sus scrofa 29105 R-SSC-9020252 https://reactome.org/PathwayBrowser/#/R-SSC-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Sus scrofa 29105 R-SSC-9020253 https://reactome.org/PathwayBrowser/#/R-SSC-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Sus scrofa 29105 R-SSC-9020257 https://reactome.org/PathwayBrowser/#/R-SSC-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Sus scrofa 29105 R-SSC-9020258 https://reactome.org/PathwayBrowser/#/R-SSC-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Sus scrofa 29105 R-SSC-9020270 https://reactome.org/PathwayBrowser/#/R-SSC-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Sus scrofa 29105 R-SSC-9024890 https://reactome.org/PathwayBrowser/#/R-SSC-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Sus scrofa 29105 R-SSC-947514 https://reactome.org/PathwayBrowser/#/R-SSC-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Sus scrofa 29105 R-SSC-9610152 https://reactome.org/PathwayBrowser/#/R-SSC-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Sus scrofa 29105 R-SSC-9610153 https://reactome.org/PathwayBrowser/#/R-SSC-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Sus scrofa 29105 R-SSC-9610154 https://reactome.org/PathwayBrowser/#/R-SSC-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Sus scrofa 29105 R-SSC-9610156 https://reactome.org/PathwayBrowser/#/R-SSC-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Sus scrofa 29105 R-SSC-9610163 https://reactome.org/PathwayBrowser/#/R-SSC-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Sus scrofa 29105 R-SSC-964958 https://reactome.org/PathwayBrowser/#/R-SSC-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Sus scrofa 29105 R-SSC-964962 https://reactome.org/PathwayBrowser/#/R-SSC-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Sus scrofa 29105 R-SSC-964970 https://reactome.org/PathwayBrowser/#/R-SSC-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Sus scrofa 29105 R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 29105 R-SSC-9727607 https://reactome.org/PathwayBrowser/#/R-SSC-9727607 MME:Zn2+ binds sacubitrilat IEA Sus scrofa 29105 R-SSC-9731661 https://reactome.org/PathwayBrowser/#/R-SSC-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Sus scrofa 29105 R-SSC-9753944 https://reactome.org/PathwayBrowser/#/R-SSC-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Sus scrofa 29105 R-SSC-975814 https://reactome.org/PathwayBrowser/#/R-SSC-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Sus scrofa 29105 R-SSC-976991 https://reactome.org/PathwayBrowser/#/R-SSC-976991 Prolactin receptor ligands bind the prolactin receptor IEA Sus scrofa 29105 R-SSC-9820566 https://reactome.org/PathwayBrowser/#/R-SSC-9820566 ZnT5 transports zinc into the golgi apparatus IEA Sus scrofa 29105 R-SSC-982810 https://reactome.org/PathwayBrowser/#/R-SSC-982810 JAK2 phosphorylation IEA Sus scrofa 29105 R-SSC-9838627 https://reactome.org/PathwayBrowser/#/R-SSC-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Sus scrofa 29105 R-SSC-9839053 https://reactome.org/PathwayBrowser/#/R-SSC-9839053 AFG3L2:SPG7 binds SMDT1 (EMRE) IEA Sus scrofa 29105 R-SSC-9839059 https://reactome.org/PathwayBrowser/#/R-SSC-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Sus scrofa 29105 R-SSC-9839105 https://reactome.org/PathwayBrowser/#/R-SSC-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Sus scrofa 29105 R-SSC-9839113 https://reactome.org/PathwayBrowser/#/R-SSC-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Sus scrofa 29105 R-SSC-9839149 https://reactome.org/PathwayBrowser/#/R-SSC-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Sus scrofa 29105 R-SSC-9840408 https://reactome.org/PathwayBrowser/#/R-SSC-9840408 OMA1 cleaves DELE1 IEA Sus scrofa 29105 R-SSC-9854463 https://reactome.org/PathwayBrowser/#/R-SSC-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Sus scrofa 29105 R-SSC-9861626 https://reactome.org/PathwayBrowser/#/R-SSC-9861626 SIRT4 cleaves lipoyl from DLAT IEA Sus scrofa 29105 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 29105 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 29105 R-XTR-1237047 https://reactome.org/PathwayBrowser/#/R-XTR-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Xenopus tropicalis 29105 R-XTR-1237059 https://reactome.org/PathwayBrowser/#/R-XTR-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Xenopus tropicalis 29105 R-XTR-1474184 https://reactome.org/PathwayBrowser/#/R-XTR-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Xenopus tropicalis 29105 R-XTR-1475017 https://reactome.org/PathwayBrowser/#/R-XTR-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Xenopus tropicalis 29105 R-XTR-1475022 https://reactome.org/PathwayBrowser/#/R-XTR-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Xenopus tropicalis 29105 R-XTR-1475025 https://reactome.org/PathwayBrowser/#/R-XTR-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Xenopus tropicalis 29105 R-XTR-1475026 https://reactome.org/PathwayBrowser/#/R-XTR-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Xenopus tropicalis 29105 R-XTR-1475028 https://reactome.org/PathwayBrowser/#/R-XTR-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Xenopus tropicalis 29105 R-XTR-1475032 https://reactome.org/PathwayBrowser/#/R-XTR-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Xenopus tropicalis 29105 R-XTR-1475422 https://reactome.org/PathwayBrowser/#/R-XTR-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Xenopus tropicalis 29105 R-XTR-1475435 https://reactome.org/PathwayBrowser/#/R-XTR-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Xenopus tropicalis 29105 R-XTR-1475436 https://reactome.org/PathwayBrowser/#/R-XTR-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Xenopus tropicalis 29105 R-XTR-158354 https://reactome.org/PathwayBrowser/#/R-XTR-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer IEA Xenopus tropicalis 29105 R-XTR-158941 https://reactome.org/PathwayBrowser/#/R-XTR-158941 plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein IEA Xenopus tropicalis 29105 R-XTR-1614605 https://reactome.org/PathwayBrowser/#/R-XTR-1614605 Persulfide sulfur is dioxygenated IEA Xenopus tropicalis 29105 R-XTR-1614654 https://reactome.org/PathwayBrowser/#/R-XTR-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Xenopus tropicalis 29105 R-XTR-189384 https://reactome.org/PathwayBrowser/#/R-XTR-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Xenopus tropicalis 29105 R-XTR-189439 https://reactome.org/PathwayBrowser/#/R-XTR-189439 ALAD condenses 2 dALAs to form PBG IEA Xenopus tropicalis 29105 R-XTR-193679 https://reactome.org/PathwayBrowser/#/R-XTR-193679 alpha-secretase cleaves the p75NTR extracellular domain IEA Xenopus tropicalis 29105 R-XTR-197198 https://reactome.org/PathwayBrowser/#/R-XTR-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 29105 R-XTR-2022368 https://reactome.org/PathwayBrowser/#/R-XTR-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Xenopus tropicalis 29105 R-XTR-2022378 https://reactome.org/PathwayBrowser/#/R-XTR-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Xenopus tropicalis 29105 R-XTR-2022379 https://reactome.org/PathwayBrowser/#/R-XTR-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Xenopus tropicalis 29105 R-XTR-2022396 https://reactome.org/PathwayBrowser/#/R-XTR-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Xenopus tropicalis 29105 R-XTR-2022398 https://reactome.org/PathwayBrowser/#/R-XTR-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Xenopus tropicalis 29105 R-XTR-2022399 https://reactome.org/PathwayBrowser/#/R-XTR-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Xenopus tropicalis 29105 R-XTR-2022405 https://reactome.org/PathwayBrowser/#/R-XTR-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 29105 R-XTR-2028294 https://reactome.org/PathwayBrowser/#/R-XTR-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Xenopus tropicalis 29105 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 29105 R-XTR-2161187 https://reactome.org/PathwayBrowser/#/R-XTR-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Xenopus tropicalis 29105 R-XTR-2161195 https://reactome.org/PathwayBrowser/#/R-XTR-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Xenopus tropicalis 29105 R-XTR-2162078 https://reactome.org/PathwayBrowser/#/R-XTR-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Xenopus tropicalis 29105 R-XTR-265153 https://reactome.org/PathwayBrowser/#/R-XTR-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Xenopus tropicalis 29105 R-XTR-265682 https://reactome.org/PathwayBrowser/#/R-XTR-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Xenopus tropicalis 29105 R-XTR-266072 https://reactome.org/PathwayBrowser/#/R-XTR-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Xenopus tropicalis 29105 R-XTR-2730867 https://reactome.org/PathwayBrowser/#/R-XTR-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Xenopus tropicalis 29105 R-XTR-3299682 https://reactome.org/PathwayBrowser/#/R-XTR-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Xenopus tropicalis 29105 R-XTR-3299691 https://reactome.org/PathwayBrowser/#/R-XTR-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Xenopus tropicalis 29105 R-XTR-3299753 https://reactome.org/PathwayBrowser/#/R-XTR-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Xenopus tropicalis 29105 R-XTR-3371385 https://reactome.org/PathwayBrowser/#/R-XTR-3371385 TNF-α is cleaved by ADAM17 (TACE) IEA Xenopus tropicalis 29105 R-XTR-3697860 https://reactome.org/PathwayBrowser/#/R-XTR-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Xenopus tropicalis 29105 R-XTR-3777112 https://reactome.org/PathwayBrowser/#/R-XTR-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Xenopus tropicalis 29105 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 29105 R-XTR-428262 https://reactome.org/PathwayBrowser/#/R-XTR-428262 ACER3 hydrolyzes phytoceramide IEA Xenopus tropicalis 29105 R-XTR-435171 https://reactome.org/PathwayBrowser/#/R-XTR-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Xenopus tropicalis 29105 R-XTR-435366 https://reactome.org/PathwayBrowser/#/R-XTR-435366 ZnT1 mediates the efflux of zinc from the cell IEA Xenopus tropicalis 29105 R-XTR-437085 https://reactome.org/PathwayBrowser/#/R-XTR-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Xenopus tropicalis 29105 R-XTR-437136 https://reactome.org/PathwayBrowser/#/R-XTR-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Xenopus tropicalis 29105 R-XTR-437139 https://reactome.org/PathwayBrowser/#/R-XTR-437139 ZnT8 transports zinc into the Golgi apparatus IEA Xenopus tropicalis 29105 R-XTR-442317 https://reactome.org/PathwayBrowser/#/R-XTR-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Xenopus tropicalis 29105 R-XTR-442387 https://reactome.org/PathwayBrowser/#/R-XTR-442387 ZIP8 mediates zinc influx into cells IEA Xenopus tropicalis 29105 R-XTR-442393 https://reactome.org/PathwayBrowser/#/R-XTR-442393 ZIP7 mediates zinc efflux from the endoplasmic reticulum IEA Xenopus tropicalis 29105 R-XTR-442422 https://reactome.org/PathwayBrowser/#/R-XTR-442422 SLC39A1-4 transports Zn2+ from extracellular region to cytosol IEA Xenopus tropicalis 29105 R-XTR-444572 https://reactome.org/PathwayBrowser/#/R-XTR-444572 Zinc is an agonist of GPR39 IEA Xenopus tropicalis 29105 R-XTR-4837364 https://reactome.org/PathwayBrowser/#/R-XTR-4837364 Secretion of SOD3 IEA Xenopus tropicalis 29105 R-XTR-5362564 https://reactome.org/PathwayBrowser/#/R-XTR-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Xenopus tropicalis 29105 R-XTR-5433074 https://reactome.org/PathwayBrowser/#/R-XTR-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 29105 R-XTR-5652195 https://reactome.org/PathwayBrowser/#/R-XTR-5652195 SORD oxidizes D-sorbitol to Fru IEA Xenopus tropicalis 29105 R-XTR-5662471 https://reactome.org/PathwayBrowser/#/R-XTR-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Xenopus tropicalis 29105 R-XTR-5662660 https://reactome.org/PathwayBrowser/#/R-XTR-5662660 Dopachrome is transformed to DHICA by DCT IEA Xenopus tropicalis 29105 R-XTR-5688276 https://reactome.org/PathwayBrowser/#/R-XTR-5688276 SIRT4 transfers ADPRib to GLUD IEA Xenopus tropicalis 29105 R-XTR-5688294 https://reactome.org/PathwayBrowser/#/R-XTR-5688294 SIRT5 deacetylates Cytochrome C IEA Xenopus tropicalis 29105 R-XTR-5691507 https://reactome.org/PathwayBrowser/#/R-XTR-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Xenopus tropicalis 29105 R-XTR-5692237 https://reactome.org/PathwayBrowser/#/R-XTR-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Xenopus tropicalis 29105 R-XTR-5693346 https://reactome.org/PathwayBrowser/#/R-XTR-5693346 CECRI deaminates Ade-Rib to Ino IEA Xenopus tropicalis 29105 R-XTR-5694071 https://reactome.org/PathwayBrowser/#/R-XTR-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Xenopus tropicalis 29105 R-XTR-5696838 https://reactome.org/PathwayBrowser/#/R-XTR-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Xenopus tropicalis 29105 R-XTR-6783221 https://reactome.org/PathwayBrowser/#/R-XTR-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Xenopus tropicalis 29105 R-XTR-6788650 https://reactome.org/PathwayBrowser/#/R-XTR-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Xenopus tropicalis 29105 R-XTR-6789072 https://reactome.org/PathwayBrowser/#/R-XTR-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Xenopus tropicalis 29105 R-XTR-6798474 https://reactome.org/PathwayBrowser/#/R-XTR-6798474 S100A8:S100A9 binds Zn2+ IEA Xenopus tropicalis 29105 R-XTR-6798489 https://reactome.org/PathwayBrowser/#/R-XTR-6798489 S100A7 or S100A7A binds Zn2+ IEA Xenopus tropicalis 29105 R-XTR-6799545 https://reactome.org/PathwayBrowser/#/R-XTR-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Xenopus tropicalis 29105 R-XTR-6799581 https://reactome.org/PathwayBrowser/#/R-XTR-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Xenopus tropicalis 29105 R-XTR-6799959 https://reactome.org/PathwayBrowser/#/R-XTR-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Xenopus tropicalis 29105 R-XTR-6799977 https://reactome.org/PathwayBrowser/#/R-XTR-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Xenopus tropicalis 29105 R-XTR-71707 https://reactome.org/PathwayBrowser/#/R-XTR-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Xenopus tropicalis 29105 R-XTR-73608 https://reactome.org/PathwayBrowser/#/R-XTR-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Xenopus tropicalis 29105 R-XTR-74255 https://reactome.org/PathwayBrowser/#/R-XTR-74255 Guanine + H2O => Xanthine + NH4+ IEA Xenopus tropicalis 29105 R-XTR-74730 https://reactome.org/PathwayBrowser/#/R-XTR-74730 Insulin degradation IEA Xenopus tropicalis 29105 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 29105 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 29105 R-XTR-880007 https://reactome.org/PathwayBrowser/#/R-XTR-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Xenopus tropicalis 29105 R-XTR-8853686 https://reactome.org/PathwayBrowser/#/R-XTR-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Xenopus tropicalis 29105 R-XTR-8866601 https://reactome.org/PathwayBrowser/#/R-XTR-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Xenopus tropicalis 29105 R-XTR-8867344 https://reactome.org/PathwayBrowser/#/R-XTR-8867344 OMA1 hydrolyses OPA1 IEA Xenopus tropicalis 29105 R-XTR-8878787 https://reactome.org/PathwayBrowser/#/R-XTR-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Xenopus tropicalis 29105 R-XTR-8940070 https://reactome.org/PathwayBrowser/#/R-XTR-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Xenopus tropicalis 29105 R-XTR-8940074 https://reactome.org/PathwayBrowser/#/R-XTR-8940074 NT5E:Zn2+ hydrolyses NMN IEA Xenopus tropicalis 29105 R-XTR-8951723 https://reactome.org/PathwayBrowser/#/R-XTR-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Xenopus tropicalis 29105 R-XTR-9018862 https://reactome.org/PathwayBrowser/#/R-XTR-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Xenopus tropicalis 29105 R-XTR-9018877 https://reactome.org/PathwayBrowser/#/R-XTR-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Xenopus tropicalis 29105 R-XTR-9020252 https://reactome.org/PathwayBrowser/#/R-XTR-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Xenopus tropicalis 29105 R-XTR-9020253 https://reactome.org/PathwayBrowser/#/R-XTR-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Xenopus tropicalis 29105 R-XTR-9020257 https://reactome.org/PathwayBrowser/#/R-XTR-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Xenopus tropicalis 29105 R-XTR-9020258 https://reactome.org/PathwayBrowser/#/R-XTR-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Xenopus tropicalis 29105 R-XTR-9020270 https://reactome.org/PathwayBrowser/#/R-XTR-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Xenopus tropicalis 29105 R-XTR-9024890 https://reactome.org/PathwayBrowser/#/R-XTR-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Xenopus tropicalis 29105 R-XTR-947514 https://reactome.org/PathwayBrowser/#/R-XTR-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Xenopus tropicalis 29105 R-XTR-9638046 https://reactome.org/PathwayBrowser/#/R-XTR-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 29105 R-XTR-964958 https://reactome.org/PathwayBrowser/#/R-XTR-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Xenopus tropicalis 29105 R-XTR-964962 https://reactome.org/PathwayBrowser/#/R-XTR-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Xenopus tropicalis 29105 R-XTR-964970 https://reactome.org/PathwayBrowser/#/R-XTR-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Xenopus tropicalis 29105 R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 29105 R-XTR-9727607 https://reactome.org/PathwayBrowser/#/R-XTR-9727607 MME:Zn2+ binds sacubitrilat IEA Xenopus tropicalis 29105 R-XTR-9731661 https://reactome.org/PathwayBrowser/#/R-XTR-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Xenopus tropicalis 29105 R-XTR-9753944 https://reactome.org/PathwayBrowser/#/R-XTR-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Xenopus tropicalis 29105 R-XTR-975814 https://reactome.org/PathwayBrowser/#/R-XTR-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Xenopus tropicalis 29105 R-XTR-9820566 https://reactome.org/PathwayBrowser/#/R-XTR-9820566 ZnT5 transports zinc into the golgi apparatus IEA Xenopus tropicalis 29105 R-XTR-9838627 https://reactome.org/PathwayBrowser/#/R-XTR-9838627 AFG3L2 binds mitochondrial inner membrane proteins IEA Xenopus tropicalis 29105 R-XTR-9839059 https://reactome.org/PathwayBrowser/#/R-XTR-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Xenopus tropicalis 29105 R-XTR-9839105 https://reactome.org/PathwayBrowser/#/R-XTR-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Xenopus tropicalis 29105 R-XTR-9839113 https://reactome.org/PathwayBrowser/#/R-XTR-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Xenopus tropicalis 29105 R-XTR-9839149 https://reactome.org/PathwayBrowser/#/R-XTR-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Xenopus tropicalis 29105 R-XTR-9840408 https://reactome.org/PathwayBrowser/#/R-XTR-9840408 OMA1 cleaves DELE1 IEA Xenopus tropicalis 29105 R-XTR-9840564 https://reactome.org/PathwayBrowser/#/R-XTR-9840564 OMA1 hydrolyzes YME1L1 IEA Xenopus tropicalis 29105 R-XTR-9861626 https://reactome.org/PathwayBrowser/#/R-XTR-9861626 SIRT4 cleaves lipoyl from DLAT IEA Xenopus tropicalis 29108 R-BTA-111881 https://reactome.org/PathwayBrowser/#/R-BTA-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Bos taurus 29108 R-BTA-111883 https://reactome.org/PathwayBrowser/#/R-BTA-111883 Hydrolysis of phosphatidylcholine IEA Bos taurus 29108 R-BTA-111915 https://reactome.org/PathwayBrowser/#/R-BTA-111915 CAMK4 autophosphorylates IEA Bos taurus 29108 R-BTA-111930 https://reactome.org/PathwayBrowser/#/R-BTA-111930 Adenylate cyclase produces cAMP IEA Bos taurus 29108 R-BTA-111956 https://reactome.org/PathwayBrowser/#/R-BTA-111956 Calmodulin activates Cam-PDE 1 IEA Bos taurus 29108 R-BTA-111966 https://reactome.org/PathwayBrowser/#/R-BTA-111966 GRK2 binds CALM1:4Ca2+ IEA Bos taurus 29108 R-BTA-111970 https://reactome.org/PathwayBrowser/#/R-BTA-111970 PKC phosphorylates GRK2 IEA Bos taurus 29108 R-BTA-114553 https://reactome.org/PathwayBrowser/#/R-BTA-114553 Activation of conventional Protein Kinase C IEA Bos taurus 29108 R-BTA-114683 https://reactome.org/PathwayBrowser/#/R-BTA-114683 Phosphorylation of Platelet Sec-1 IEA Bos taurus 29108 R-BTA-114684 https://reactome.org/PathwayBrowser/#/R-BTA-114684 Phosphorylation of Syntaxin-4 IEA Bos taurus 29108 R-BTA-114697 https://reactome.org/PathwayBrowser/#/R-BTA-114697 Activated thrombin (factor IIa) cleaves PAR3,4, activating them IEA Bos taurus 29108 R-BTA-1168373 https://reactome.org/PathwayBrowser/#/R-BTA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Bos taurus 29108 R-BTA-1168376 https://reactome.org/PathwayBrowser/#/R-BTA-1168376 STIM1 oligomerizes IEA Bos taurus 29108 R-BTA-1168635 https://reactome.org/PathwayBrowser/#/R-BTA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Bos taurus 29108 R-BTA-1183128 https://reactome.org/PathwayBrowser/#/R-BTA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Bos taurus 29108 R-BTA-139854 https://reactome.org/PathwayBrowser/#/R-BTA-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Bos taurus 29108 R-BTA-139855 https://reactome.org/PathwayBrowser/#/R-BTA-139855 P2X1-mediated entry of Ca++ from plasma IEA Bos taurus 29108 R-BTA-139941 https://reactome.org/PathwayBrowser/#/R-BTA-139941 Binding of IP3 to IP3 receptor IEA Bos taurus 29108 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 29108 R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 29108 R-BTA-140686 https://reactome.org/PathwayBrowser/#/R-BTA-140686 factor Va + factor Xa -> Va:Xa complex (prothrombinase) IEA Bos taurus 29108 R-BTA-140696 https://reactome.org/PathwayBrowser/#/R-BTA-140696 factor V -> factor Va + factor V activation peptide IEA Bos taurus 29108 R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 29108 R-BTA-140736 https://reactome.org/PathwayBrowser/#/R-BTA-140736 factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) IEA Bos taurus 29108 R-BTA-140748 https://reactome.org/PathwayBrowser/#/R-BTA-140748 tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex IEA Bos taurus 29108 R-BTA-140769 https://reactome.org/PathwayBrowser/#/R-BTA-140769 factor VII -> factor VIIa IEA Bos taurus 29108 R-BTA-140777 https://reactome.org/PathwayBrowser/#/R-BTA-140777 factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) IEA Bos taurus 29108 R-BTA-140783 https://reactome.org/PathwayBrowser/#/R-BTA-140783 tissue factor (TF) + factor VII (F7) -> TF:F7 complex IEA Bos taurus 29108 R-BTA-140791 https://reactome.org/PathwayBrowser/#/R-BTA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Bos taurus 29108 R-BTA-140823 https://reactome.org/PathwayBrowser/#/R-BTA-140823 factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) IEA Bos taurus 29108 R-BTA-140825 https://reactome.org/PathwayBrowser/#/R-BTA-140825 TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa IEA Bos taurus 29108 R-BTA-140847 https://reactome.org/PathwayBrowser/#/R-BTA-140847 factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain IEA Bos taurus 29108 R-BTA-140870 https://reactome.org/PathwayBrowser/#/R-BTA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Bos taurus 29108 R-BTA-140872 https://reactome.org/PathwayBrowser/#/R-BTA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Bos taurus 29108 R-BTA-141026 https://reactome.org/PathwayBrowser/#/R-BTA-141026 Activated protein C cleaves factor Va to factor Vi intermediate form IEA Bos taurus 29108 R-BTA-141040 https://reactome.org/PathwayBrowser/#/R-BTA-141040 Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C IEA Bos taurus 29108 R-BTA-141046 https://reactome.org/PathwayBrowser/#/R-BTA-141046 activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin IEA Bos taurus 29108 R-BTA-1482604 https://reactome.org/PathwayBrowser/#/R-BTA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Bos taurus 29108 R-BTA-1482612 https://reactome.org/PathwayBrowser/#/R-BTA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 29108 R-BTA-1482656 https://reactome.org/PathwayBrowser/#/R-BTA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Bos taurus 29108 R-BTA-1482679 https://reactome.org/PathwayBrowser/#/R-BTA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Bos taurus 29108 R-BTA-1482685 https://reactome.org/PathwayBrowser/#/R-BTA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 29108 R-BTA-1482759 https://reactome.org/PathwayBrowser/#/R-BTA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Bos taurus 29108 R-BTA-1482771 https://reactome.org/PathwayBrowser/#/R-BTA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Bos taurus 29108 R-BTA-1482776 https://reactome.org/PathwayBrowser/#/R-BTA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Bos taurus 29108 R-BTA-1482816 https://reactome.org/PathwayBrowser/#/R-BTA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Bos taurus 29108 R-BTA-1482825 https://reactome.org/PathwayBrowser/#/R-BTA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Bos taurus 29108 R-BTA-1482828 https://reactome.org/PathwayBrowser/#/R-BTA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Bos taurus 29108 R-BTA-1482856 https://reactome.org/PathwayBrowser/#/R-BTA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Bos taurus 29108 R-BTA-1482862 https://reactome.org/PathwayBrowser/#/R-BTA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Bos taurus 29108 R-BTA-1482868 https://reactome.org/PathwayBrowser/#/R-BTA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Bos taurus 29108 R-BTA-1482884 https://reactome.org/PathwayBrowser/#/R-BTA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Bos taurus 29108 R-BTA-1482887 https://reactome.org/PathwayBrowser/#/R-BTA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Bos taurus 29108 R-BTA-1482897 https://reactome.org/PathwayBrowser/#/R-BTA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Bos taurus 29108 R-BTA-1482900 https://reactome.org/PathwayBrowser/#/R-BTA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Bos taurus 29108 R-BTA-1482907 https://reactome.org/PathwayBrowser/#/R-BTA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Bos taurus 29108 R-BTA-1497784 https://reactome.org/PathwayBrowser/#/R-BTA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Bos taurus 29108 R-BTA-1497796 https://reactome.org/PathwayBrowser/#/R-BTA-1497796 BH2 binding can lead to eNOS uncoupling IEA Bos taurus 29108 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 29108 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 29108 R-BTA-158164 https://reactome.org/PathwayBrowser/#/R-BTA-158164 factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) IEA Bos taurus 29108 R-BTA-158278 https://reactome.org/PathwayBrowser/#/R-BTA-158278 factor VIIIa + factor IXa -> factor VIIIa:factor IXa IEA Bos taurus 29108 R-BTA-158333 https://reactome.org/PathwayBrowser/#/R-BTA-158333 factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) IEA Bos taurus 29108 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 29108 R-BTA-1602368 https://reactome.org/PathwayBrowser/#/R-BTA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Bos taurus 29108 R-BTA-1602374 https://reactome.org/PathwayBrowser/#/R-BTA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Bos taurus 29108 R-BTA-1602377 https://reactome.org/PathwayBrowser/#/R-BTA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Bos taurus 29108 R-BTA-1602398 https://reactome.org/PathwayBrowser/#/R-BTA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Bos taurus 29108 R-BTA-1602417 https://reactome.org/PathwayBrowser/#/R-BTA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Bos taurus 29108 R-BTA-1602446 https://reactome.org/PathwayBrowser/#/R-BTA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Bos taurus 29108 R-BTA-1606789 https://reactome.org/PathwayBrowser/#/R-BTA-1606789 ARSB hydrolyses DS IEA Bos taurus 29108 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 29108 R-BTA-1606839 https://reactome.org/PathwayBrowser/#/R-BTA-1606839 ARSC hydrolyzes steroid sulfates IEA Bos taurus 29108 R-BTA-1614362 https://reactome.org/PathwayBrowser/#/R-BTA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Bos taurus 29108 R-BTA-166721 https://reactome.org/PathwayBrowser/#/R-BTA-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa IEA Bos taurus 29108 R-BTA-166726 https://reactome.org/PathwayBrowser/#/R-BTA-166726 Activation of MASPs IEA Bos taurus 29108 R-BTA-166753 https://reactome.org/PathwayBrowser/#/R-BTA-166753 Conversion of C4 into C4a and C4b IEA Bos taurus 29108 R-BTA-166792 https://reactome.org/PathwayBrowser/#/R-BTA-166792 Conversion of C2 into C2a and C2b IEA Bos taurus 29108 R-BTA-1675928 https://reactome.org/PathwayBrowser/#/R-BTA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Bos taurus 29108 R-BTA-1675939 https://reactome.org/PathwayBrowser/#/R-BTA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Bos taurus 29108 R-BTA-1675961 https://reactome.org/PathwayBrowser/#/R-BTA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Bos taurus 29108 R-BTA-1676024 https://reactome.org/PathwayBrowser/#/R-BTA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Bos taurus 29108 R-BTA-1676109 https://reactome.org/PathwayBrowser/#/R-BTA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Bos taurus 29108 R-BTA-1676206 https://reactome.org/PathwayBrowser/#/R-BTA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Bos taurus 29108 R-BTA-1678650 https://reactome.org/PathwayBrowser/#/R-BTA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Bos taurus 29108 R-BTA-173626 https://reactome.org/PathwayBrowser/#/R-BTA-173626 Activation of C1r IEA Bos taurus 29108 R-BTA-1793182 https://reactome.org/PathwayBrowser/#/R-BTA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Bos taurus 29108 R-BTA-1793207 https://reactome.org/PathwayBrowser/#/R-BTA-1793207 ARSB hydrolyses C4S/C6S chains IEA Bos taurus 29108 R-BTA-1855153 https://reactome.org/PathwayBrowser/#/R-BTA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Bos taurus 29108 R-BTA-1855177 https://reactome.org/PathwayBrowser/#/R-BTA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Bos taurus 29108 R-BTA-1855214 https://reactome.org/PathwayBrowser/#/R-BTA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Bos taurus 29108 R-BTA-1855221 https://reactome.org/PathwayBrowser/#/R-BTA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Bos taurus 29108 R-BTA-187020 https://reactome.org/PathwayBrowser/#/R-BTA-187020 Part of pro-beta-NGF is processed to mature beta-NGF IEA Bos taurus 29108 R-BTA-202110 https://reactome.org/PathwayBrowser/#/R-BTA-202110 eNOS:Caveolin-1 complex binds to CaM IEA Bos taurus 29108 R-BTA-202111 https://reactome.org/PathwayBrowser/#/R-BTA-202111 AKT1 phosphorylates eNOS IEA Bos taurus 29108 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 29108 R-BTA-202129 https://reactome.org/PathwayBrowser/#/R-BTA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Bos taurus 29108 R-BTA-202144 https://reactome.org/PathwayBrowser/#/R-BTA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Bos taurus 29108 R-BTA-2025890 https://reactome.org/PathwayBrowser/#/R-BTA-2025890 Calcineurin binds NFATC1,2,3 IEA Bos taurus 29108 R-BTA-2089943 https://reactome.org/PathwayBrowser/#/R-BTA-2089943 TRPC1 translocates calcium from the extracellular region to the cytosol IEA Bos taurus 29108 R-BTA-210420 https://reactome.org/PathwayBrowser/#/R-BTA-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Bos taurus 29108 R-BTA-210430 https://reactome.org/PathwayBrowser/#/R-BTA-210430 Release of L-Glutamate at the synapse IEA Bos taurus 29108 R-BTA-2160884 https://reactome.org/PathwayBrowser/#/R-BTA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Bos taurus 29108 R-BTA-2160892 https://reactome.org/PathwayBrowser/#/R-BTA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Bos taurus 29108 R-BTA-2161768 https://reactome.org/PathwayBrowser/#/R-BTA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Bos taurus 29108 R-BTA-2161907 https://reactome.org/PathwayBrowser/#/R-BTA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Bos taurus 29108 R-BTA-2161917 https://reactome.org/PathwayBrowser/#/R-BTA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Bos taurus 29108 R-BTA-2248891 https://reactome.org/PathwayBrowser/#/R-BTA-2248891 M6PR transports activated ARSA to the lysosome IEA Bos taurus 29108 R-BTA-2424243 https://reactome.org/PathwayBrowser/#/R-BTA-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Bos taurus 29108 R-BTA-2514867 https://reactome.org/PathwayBrowser/#/R-BTA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Bos taurus 29108 R-BTA-2534148 https://reactome.org/PathwayBrowser/#/R-BTA-2534148 Nckx1 exchanges Na+ for Ca2+/K+ TAS Bos taurus 29108 R-BTA-2534359 https://reactome.org/PathwayBrowser/#/R-BTA-2534359 CatSper Channel Mediated Calcium Transport IEA Bos taurus 29108 R-BTA-2581474 https://reactome.org/PathwayBrowser/#/R-BTA-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Bos taurus 29108 R-BTA-2586748 https://reactome.org/PathwayBrowser/#/R-BTA-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ IEA Bos taurus 29108 R-BTA-264976 https://reactome.org/PathwayBrowser/#/R-BTA-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Bos taurus 29108 R-BTA-265153 https://reactome.org/PathwayBrowser/#/R-BTA-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Bos taurus 29108 R-BTA-265296 https://reactome.org/PathwayBrowser/#/R-BTA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Bos taurus 29108 R-BTA-265301 https://reactome.org/PathwayBrowser/#/R-BTA-265301 Corticotropin cleavage from POMC IEA Bos taurus 29108 R-BTA-265645 https://reactome.org/PathwayBrowser/#/R-BTA-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Bos taurus 29108 R-BTA-266050 https://reactome.org/PathwayBrowser/#/R-BTA-266050 LTA4 is converted to LTC4 by LTC4S IEA Bos taurus 29108 R-BTA-266051 https://reactome.org/PathwayBrowser/#/R-BTA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Bos taurus 29108 R-BTA-2684901 https://reactome.org/PathwayBrowser/#/R-BTA-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Bos taurus 29108 R-BTA-2685505 https://reactome.org/PathwayBrowser/#/R-BTA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Bos taurus 29108 R-BTA-2730664 https://reactome.org/PathwayBrowser/#/R-BTA-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Bos taurus 29108 R-BTA-2730849 https://reactome.org/PathwayBrowser/#/R-BTA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Bos taurus 29108 R-BTA-2730867 https://reactome.org/PathwayBrowser/#/R-BTA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Bos taurus 29108 R-BTA-2730872 https://reactome.org/PathwayBrowser/#/R-BTA-2730872 Activation of Calcineurin IEA Bos taurus 29108 R-BTA-2744242 https://reactome.org/PathwayBrowser/#/R-BTA-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Bos taurus 29108 R-BTA-2744361 https://reactome.org/PathwayBrowser/#/R-BTA-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Bos taurus 29108 R-BTA-2855020 https://reactome.org/PathwayBrowser/#/R-BTA-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Bos taurus 29108 R-BTA-2855054 https://reactome.org/PathwayBrowser/#/R-BTA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Bos taurus 29108 R-BTA-2855125 https://reactome.org/PathwayBrowser/#/R-BTA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Bos taurus 29108 R-BTA-3229181 https://reactome.org/PathwayBrowser/#/R-BTA-3229181 CALM1:Ca2+ binds CNG channel IEA Bos taurus 29108 R-BTA-3270622 https://reactome.org/PathwayBrowser/#/R-BTA-3270622 Rcvrn:Ca2+ binds to and inhibits Grk1 TAS Bos taurus 29108 R-BTA-3295579 https://reactome.org/PathwayBrowser/#/R-BTA-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Bos taurus 29108 R-BTA-354066 https://reactome.org/PathwayBrowser/#/R-BTA-354066 Translocation of PTK2 to Focal complexes IEA Bos taurus 29108 R-BTA-354073 https://reactome.org/PathwayBrowser/#/R-BTA-354073 Autophosphorylation of PTK2 at Y397 IEA Bos taurus 29108 R-BTA-354087 https://reactome.org/PathwayBrowser/#/R-BTA-354087 Recruitment of GRB2 to p-PTK2 IEA Bos taurus 29108 R-BTA-354124 https://reactome.org/PathwayBrowser/#/R-BTA-354124 Phosphorylation of pPTK2 by SRC IEA Bos taurus 29108 R-BTA-354149 https://reactome.org/PathwayBrowser/#/R-BTA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Bos taurus 29108 R-BTA-354165 https://reactome.org/PathwayBrowser/#/R-BTA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Bos taurus 29108 R-BTA-354173 https://reactome.org/PathwayBrowser/#/R-BTA-354173 Activation of Rap1 by cytosolic GEFs IEA Bos taurus 29108 R-BTA-372448 https://reactome.org/PathwayBrowser/#/R-BTA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Bos taurus 29108 R-BTA-372693 https://reactome.org/PathwayBrowser/#/R-BTA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Bos taurus 29108 R-BTA-372697 https://reactome.org/PathwayBrowser/#/R-BTA-372697 Crk binding to p130cas IEA Bos taurus 29108 R-BTA-372705 https://reactome.org/PathwayBrowser/#/R-BTA-372705 Recruitment of BCAR1 to PTK2 complex IEA Bos taurus 29108 R-BTA-375176 https://reactome.org/PathwayBrowser/#/R-BTA-375176 Inactive catalytic PP2B is activated by the binding of calmodulin TAS Bos taurus 29108 R-BTA-377640 https://reactome.org/PathwayBrowser/#/R-BTA-377640 Autophosphorylation of SRC IEA Bos taurus 29108 R-BTA-377641 https://reactome.org/PathwayBrowser/#/R-BTA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Bos taurus 29108 R-BTA-377643 https://reactome.org/PathwayBrowser/#/R-BTA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Bos taurus 29108 R-BTA-377644 https://reactome.org/PathwayBrowser/#/R-BTA-377644 Release of CSK from SRC IEA Bos taurus 29108 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 29108 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 29108 R-BTA-3827958 https://reactome.org/PathwayBrowser/#/R-BTA-3827958 E-cadherin degradation by MMP9, KLK7 IEA Bos taurus 29108 R-BTA-389463 https://reactome.org/PathwayBrowser/#/R-BTA-389463 Proteinase-activated receptors can bind thrombin IEA Bos taurus 29108 R-BTA-390593 https://reactome.org/PathwayBrowser/#/R-BTA-390593 ATP Hydrolysis By Myosin IEA Bos taurus 29108 R-BTA-390595 https://reactome.org/PathwayBrowser/#/R-BTA-390595 Calcium Binds Troponin-C IEA Bos taurus 29108 R-BTA-390597 https://reactome.org/PathwayBrowser/#/R-BTA-390597 Release Of ADP From Myosin IEA Bos taurus 29108 R-BTA-390598 https://reactome.org/PathwayBrowser/#/R-BTA-390598 Myosin Binds ATP IEA Bos taurus 29108 R-BTA-399712 https://reactome.org/PathwayBrowser/#/R-BTA-399712 Activation of Ca permeable AMPA receptors IEA Bos taurus 29108 R-BTA-416639 https://reactome.org/PathwayBrowser/#/R-BTA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Bos taurus 29108 R-BTA-418309 https://reactome.org/PathwayBrowser/#/R-BTA-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Bos taurus 29108 R-BTA-418365 https://reactome.org/PathwayBrowser/#/R-BTA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Bos taurus 29108 R-BTA-419001 https://reactome.org/PathwayBrowser/#/R-BTA-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Bos taurus 29108 R-BTA-420724 https://reactome.org/PathwayBrowser/#/R-BTA-420724 CASR binds Ca2+ IEA Bos taurus 29108 R-BTA-421007 https://reactome.org/PathwayBrowser/#/R-BTA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Bos taurus 29108 R-BTA-422021 https://reactome.org/PathwayBrowser/#/R-BTA-422021 PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin IEA Bos taurus 29108 R-BTA-4224014 https://reactome.org/PathwayBrowser/#/R-BTA-4224014 E-cadherin degradation by ADAM10, ADAM15 IEA Bos taurus 29108 R-BTA-425661 https://reactome.org/PathwayBrowser/#/R-BTA-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Bos taurus 29108 R-BTA-425678 https://reactome.org/PathwayBrowser/#/R-BTA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Bos taurus 29108 R-BTA-425822 https://reactome.org/PathwayBrowser/#/R-BTA-425822 K+-independent Li+/Ca2+ exchanger transport IEA Bos taurus 29108 R-BTA-426223 https://reactome.org/PathwayBrowser/#/R-BTA-426223 Cation influx mediated by TRPC3/6/7 IEA Bos taurus 29108 R-BTA-427910 https://reactome.org/PathwayBrowser/#/R-BTA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Bos taurus 29108 R-BTA-428262 https://reactome.org/PathwayBrowser/#/R-BTA-428262 ACER3 hydrolyzes phytoceramide IEA Bos taurus 29108 R-BTA-429016 https://reactome.org/PathwayBrowser/#/R-BTA-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Bos taurus 29108 R-BTA-429415 https://reactome.org/PathwayBrowser/#/R-BTA-429415 SYK binds to integrin alphaIIb beta3 IEA Bos taurus 29108 R-BTA-429441 https://reactome.org/PathwayBrowser/#/R-BTA-429441 SYK activation by SRC IEA Bos taurus 29108 R-BTA-429529 https://reactome.org/PathwayBrowser/#/R-BTA-429529 Thrombin binding to GP1b:IX:V IEA Bos taurus 29108 R-BTA-432164 https://reactome.org/PathwayBrowser/#/R-BTA-432164 Ca2+ influx into the post-synaptic cell IEA Bos taurus 29108 R-BTA-4332358 https://reactome.org/PathwayBrowser/#/R-BTA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Bos taurus 29108 R-BTA-4332359 https://reactome.org/PathwayBrowser/#/R-BTA-4332359 Active calmodulin binds CAMK2 IEA Bos taurus 29108 R-BTA-4332363 https://reactome.org/PathwayBrowser/#/R-BTA-4332363 Autophosphorylation and activation of CAMK2 IEA Bos taurus 29108 R-BTA-438037 https://reactome.org/PathwayBrowser/#/R-BTA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Bos taurus 29108 R-BTA-442749 https://reactome.org/PathwayBrowser/#/R-BTA-442749 CaMKK autophosphorylates in the nucleus IEA Bos taurus 29108 R-BTA-445699 https://reactome.org/PathwayBrowser/#/R-BTA-445699 ATP Hydrolysis By Myosin IEA Bos taurus 29108 R-BTA-445700 https://reactome.org/PathwayBrowser/#/R-BTA-445700 Myosin Binds ATP IEA Bos taurus 29108 R-BTA-445704 https://reactome.org/PathwayBrowser/#/R-BTA-445704 Calcium Binds Caldesmon IEA Bos taurus 29108 R-BTA-445705 https://reactome.org/PathwayBrowser/#/R-BTA-445705 Release Of ADP From Myosin IEA Bos taurus 29108 R-BTA-445797 https://reactome.org/PathwayBrowser/#/R-BTA-445797 MYLK (MLCK) Active Calmodulin Binding IEA Bos taurus 29108 R-BTA-445813 https://reactome.org/PathwayBrowser/#/R-BTA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Bos taurus 29108 R-BTA-451311 https://reactome.org/PathwayBrowser/#/R-BTA-451311 Activation of Ca-permeable Kainate receptors IEA Bos taurus 29108 R-BTA-4551451 https://reactome.org/PathwayBrowser/#/R-BTA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Bos taurus 29108 R-BTA-4551465 https://reactome.org/PathwayBrowser/#/R-BTA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Bos taurus 29108 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 29108 R-BTA-5138432 https://reactome.org/PathwayBrowser/#/R-BTA-5138432 DVL2 is phosphorylated by PKC IEA Bos taurus 29108 R-BTA-5218813 https://reactome.org/PathwayBrowser/#/R-BTA-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Bos taurus 29108 R-BTA-5218823 https://reactome.org/PathwayBrowser/#/R-BTA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Bos taurus 29108 R-BTA-5223304 https://reactome.org/PathwayBrowser/#/R-BTA-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Bos taurus 29108 R-BTA-5229194 https://reactome.org/PathwayBrowser/#/R-BTA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Bos taurus 29108 R-BTA-5333671 https://reactome.org/PathwayBrowser/#/R-BTA-5333671 CLCAs self cleave IEA Bos taurus 29108 R-BTA-5333678 https://reactome.org/PathwayBrowser/#/R-BTA-5333678 CPNEs bind PL IEA Bos taurus 29108 R-BTA-5576895 https://reactome.org/PathwayBrowser/#/R-BTA-5576895 SCNAs:SNCBs transport Na+ from extracellular region to cytosol IEA Bos taurus 29108 R-BTA-5577213 https://reactome.org/PathwayBrowser/#/R-BTA-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Bos taurus 29108 R-BTA-5578883 https://reactome.org/PathwayBrowser/#/R-BTA-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Bos taurus 29108 R-BTA-5591040 https://reactome.org/PathwayBrowser/#/R-BTA-5591040 Activated protein C cleaves Factor Va intermediate form for Factor Va IEA Bos taurus 29108 R-BTA-5591052 https://reactome.org/PathwayBrowser/#/R-BTA-5591052 PROCR binds Protein C IEA Bos taurus 29108 R-BTA-5591086 https://reactome.org/PathwayBrowser/#/R-BTA-5591086 SERPINA5 binds activated protein C IEA Bos taurus 29108 R-BTA-5602080 https://reactome.org/PathwayBrowser/#/R-BTA-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Bos taurus 29108 R-BTA-5603467 https://reactome.org/PathwayBrowser/#/R-BTA-5603467 Activated protein C is released from PROCR IEA Bos taurus 29108 R-BTA-5604929 https://reactome.org/PathwayBrowser/#/R-BTA-5604929 Activated protein C binds Protein S IEA Bos taurus 29108 R-BTA-5606996 https://reactome.org/PathwayBrowser/#/R-BTA-5606996 Soluble PROCR binds activated protein C IEA Bos taurus 29108 R-BTA-5607002 https://reactome.org/PathwayBrowser/#/R-BTA-5607002 Activated protein C cleaves factor VIIIa IEA Bos taurus 29108 R-BTA-5607058 https://reactome.org/PathwayBrowser/#/R-BTA-5607058 Activated protein C:PROCR binds F2R IEA Bos taurus 29108 R-BTA-5626316 https://reactome.org/PathwayBrowser/#/R-BTA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Bos taurus 29108 R-BTA-5626507 https://reactome.org/PathwayBrowser/#/R-BTA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Bos taurus 29108 R-BTA-5626549 https://reactome.org/PathwayBrowser/#/R-BTA-5626549 IQGAPs bind CALM1 IEA Bos taurus 29108 R-BTA-5668629 https://reactome.org/PathwayBrowser/#/R-BTA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Bos taurus 29108 R-BTA-5672304 https://reactome.org/PathwayBrowser/#/R-BTA-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 IEA Bos taurus 29108 R-BTA-5672965 https://reactome.org/PathwayBrowser/#/R-BTA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Bos taurus 29108 R-BTA-5672969 https://reactome.org/PathwayBrowser/#/R-BTA-5672969 Phosphorylation of RAF IEA Bos taurus 29108 R-BTA-5672972 https://reactome.org/PathwayBrowser/#/R-BTA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Bos taurus 29108 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 29108 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 29108 R-BTA-5672980 https://reactome.org/PathwayBrowser/#/R-BTA-5672980 Dissociation of RAS:RAF complex IEA Bos taurus 29108 R-BTA-5694018 https://reactome.org/PathwayBrowser/#/R-BTA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Bos taurus 29108 R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 29108 R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 29108 R-BTA-622326 https://reactome.org/PathwayBrowser/#/R-BTA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Bos taurus 29108 R-BTA-629595 https://reactome.org/PathwayBrowser/#/R-BTA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 29108 R-BTA-6798474 https://reactome.org/PathwayBrowser/#/R-BTA-6798474 S100A8:S100A9 binds Zn2+ IEA Bos taurus 29108 R-BTA-6798489 https://reactome.org/PathwayBrowser/#/R-BTA-6798489 S100A7 or S100A7A binds Zn2+ IEA Bos taurus 29108 R-BTA-6798528 https://reactome.org/PathwayBrowser/#/R-BTA-6798528 S100A8:S100A9 binds Mn2+ IEA Bos taurus 29108 R-BTA-6804527 https://reactome.org/PathwayBrowser/#/R-BTA-6804527 INTL1 binds bacterial glycans IEA Bos taurus 29108 R-BTA-6805943 https://reactome.org/PathwayBrowser/#/R-BTA-6805943 S100A1 binds TLR4:LY96 IEA Bos taurus 29108 R-BTA-71181 https://reactome.org/PathwayBrowser/#/R-BTA-71181 FAH cleaves 4FAA IEA Bos taurus 29108 R-BTA-71401 https://reactome.org/PathwayBrowser/#/R-BTA-71401 OGDH dimer decarboxylates 2-OG IEA Bos taurus 29108 R-BTA-71541 https://reactome.org/PathwayBrowser/#/R-BTA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Bos taurus 29108 R-BTA-71588 https://reactome.org/PathwayBrowser/#/R-BTA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Bos taurus 29108 R-BTA-74447 https://reactome.org/PathwayBrowser/#/R-BTA-74447 Calcium binds calmodulin TAS Bos taurus 29108 R-BTA-74885 https://reactome.org/PathwayBrowser/#/R-BTA-74885 GUCYs converts GTP to cGMP IEA Bos taurus 29108 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 29108 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 29108 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 29108 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 29108 R-BTA-74948 https://reactome.org/PathwayBrowser/#/R-BTA-74948 PP2A dephosphorylates p-RHO to RHO IEA Bos taurus 29108 R-BTA-8848658 https://reactome.org/PathwayBrowser/#/R-BTA-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Bos taurus 29108 R-BTA-8850846 https://reactome.org/PathwayBrowser/#/R-BTA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Bos taurus 29108 R-BTA-8850854 https://reactome.org/PathwayBrowser/#/R-BTA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Bos taurus 29108 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 29108 R-BTA-8851110 https://reactome.org/PathwayBrowser/#/R-BTA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Bos taurus 29108 R-BTA-8851129 https://reactome.org/PathwayBrowser/#/R-BTA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Bos taurus 29108 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 29108 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 29108 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 29108 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 29108 R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 29108 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 29108 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 29108 R-BTA-8852509 https://reactome.org/PathwayBrowser/#/R-BTA-8852509 CL-LK binds carbohydrates on target cell surface IEA Bos taurus 29108 R-BTA-8852716 https://reactome.org/PathwayBrowser/#/R-BTA-8852716 Thrombin, ELANE cleave C5 IEA Bos taurus 29108 R-BTA-8857662 https://reactome.org/PathwayBrowser/#/R-BTA-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Bos taurus 29108 R-BTA-8862771 https://reactome.org/PathwayBrowser/#/R-BTA-8862771 PLA2G2A binds bacterial phospholipids IEA Bos taurus 29108 R-BTA-8878787 https://reactome.org/PathwayBrowser/#/R-BTA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Bos taurus 29108 R-BTA-888589 https://reactome.org/PathwayBrowser/#/R-BTA-888589 Release of GABA at the synapse IEA Bos taurus 29108 R-BTA-8932633 https://reactome.org/PathwayBrowser/#/R-BTA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Bos taurus 29108 R-BTA-8949178 https://reactome.org/PathwayBrowser/#/R-BTA-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Bos taurus 29108 R-BTA-8949688 https://reactome.org/PathwayBrowser/#/R-BTA-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Bos taurus 29108 R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 29108 R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 29108 R-BTA-9015379 https://reactome.org/PathwayBrowser/#/R-BTA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Bos taurus 29108 R-BTA-936883 https://reactome.org/PathwayBrowser/#/R-BTA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Bos taurus 29108 R-BTA-9603302 https://reactome.org/PathwayBrowser/#/R-BTA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Bos taurus 29108 R-BTA-9619355 https://reactome.org/PathwayBrowser/#/R-BTA-9619355 CaMKK autophosphorylates in the cytosol IEA Bos taurus 29108 R-BTA-9619376 https://reactome.org/PathwayBrowser/#/R-BTA-9619376 CAMK1 binds calmodulin IEA Bos taurus 29108 R-BTA-9626848 https://reactome.org/PathwayBrowser/#/R-BTA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Bos taurus 29108 R-BTA-9648983 https://reactome.org/PathwayBrowser/#/R-BTA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Bos taurus 29108 R-BTA-9653585 https://reactome.org/PathwayBrowser/#/R-BTA-9653585 S-Farn-Me KRAS4B binds calmodulin IEA Bos taurus 29108 R-BTA-9654521 https://reactome.org/PathwayBrowser/#/R-BTA-9654521 Calmodulin dissociates KRAS4B from the plasma membrane IEA Bos taurus 29108 R-BTA-9654523 https://reactome.org/PathwayBrowser/#/R-BTA-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Bos taurus 29108 R-BTA-9654525 https://reactome.org/PathwayBrowser/#/R-BTA-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ IEA Bos taurus 29108 R-BTA-9654533 https://reactome.org/PathwayBrowser/#/R-BTA-9654533 KRAS4B recycles to the plasma membrane IEA Bos taurus 29108 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus 29108 R-BTA-9657603 https://reactome.org/PathwayBrowser/#/R-BTA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Bos taurus 29108 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 29108 R-BTA-9657608 https://reactome.org/PathwayBrowser/#/R-BTA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Bos taurus 29108 R-BTA-9659568 https://reactome.org/PathwayBrowser/#/R-BTA-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Bos taurus 29108 R-BTA-9701055 https://reactome.org/PathwayBrowser/#/R-BTA-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Bos taurus 29108 R-BTA-9701141 https://reactome.org/PathwayBrowser/#/R-BTA-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Bos taurus 29108 R-BTA-9707186 https://reactome.org/PathwayBrowser/#/R-BTA-9707186 ALOX5 binds ALOX5 inhibitors IEA Bos taurus 29108 R-BTA-9708859 https://reactome.org/PathwayBrowser/#/R-BTA-9708859 Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it IEA Bos taurus 29108 R-BTA-9717215 https://reactome.org/PathwayBrowser/#/R-BTA-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Bos taurus 29108 R-BTA-975311 https://reactome.org/PathwayBrowser/#/R-BTA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Bos taurus 29108 R-BTA-9756177 https://reactome.org/PathwayBrowser/#/R-BTA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Bos taurus 29108 R-BTA-9840949 https://reactome.org/PathwayBrowser/#/R-BTA-9840949 ARSA removes sulfate from SM3 IEA Bos taurus 29108 R-BTA-9853499 https://reactome.org/PathwayBrowser/#/R-BTA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 29108 R-BTA-9853512 https://reactome.org/PathwayBrowser/#/R-BTA-9853512 DLST transfers succinyl to CoA IEA Bos taurus 29108 R-CEL-111930 https://reactome.org/PathwayBrowser/#/R-CEL-111930 Adenylate cyclase produces cAMP IEA Caenorhabditis elegans 29108 R-CEL-111956 https://reactome.org/PathwayBrowser/#/R-CEL-111956 Calmodulin activates Cam-PDE 1 IEA Caenorhabditis elegans 29108 R-CEL-111966 https://reactome.org/PathwayBrowser/#/R-CEL-111966 GRK2 binds CALM1:4Ca2+ IEA Caenorhabditis elegans 29108 R-CEL-111970 https://reactome.org/PathwayBrowser/#/R-CEL-111970 PKC phosphorylates GRK2 IEA Caenorhabditis elegans 29108 R-CEL-114553 https://reactome.org/PathwayBrowser/#/R-CEL-114553 Activation of conventional Protein Kinase C IEA Caenorhabditis elegans 29108 R-CEL-114683 https://reactome.org/PathwayBrowser/#/R-CEL-114683 Phosphorylation of Platelet Sec-1 IEA Caenorhabditis elegans 29108 R-CEL-114684 https://reactome.org/PathwayBrowser/#/R-CEL-114684 Phosphorylation of Syntaxin-4 IEA Caenorhabditis elegans 29108 R-CEL-1168373 https://reactome.org/PathwayBrowser/#/R-CEL-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Caenorhabditis elegans 29108 R-CEL-1168376 https://reactome.org/PathwayBrowser/#/R-CEL-1168376 STIM1 oligomerizes IEA Caenorhabditis elegans 29108 R-CEL-139854 https://reactome.org/PathwayBrowser/#/R-CEL-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Caenorhabditis elegans 29108 R-CEL-139941 https://reactome.org/PathwayBrowser/#/R-CEL-139941 Binding of IP3 to IP3 receptor IEA Caenorhabditis elegans 29108 R-CEL-1482679 https://reactome.org/PathwayBrowser/#/R-CEL-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Caenorhabditis elegans 29108 R-CEL-1482776 https://reactome.org/PathwayBrowser/#/R-CEL-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Caenorhabditis elegans 29108 R-CEL-1482816 https://reactome.org/PathwayBrowser/#/R-CEL-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Caenorhabditis elegans 29108 R-CEL-1482868 https://reactome.org/PathwayBrowser/#/R-CEL-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Caenorhabditis elegans 29108 R-CEL-1482887 https://reactome.org/PathwayBrowser/#/R-CEL-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Caenorhabditis elegans 29108 R-CEL-1482907 https://reactome.org/PathwayBrowser/#/R-CEL-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Caenorhabditis elegans 29108 R-CEL-1497784 https://reactome.org/PathwayBrowser/#/R-CEL-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Caenorhabditis elegans 29108 R-CEL-1497796 https://reactome.org/PathwayBrowser/#/R-CEL-1497796 BH2 binding can lead to eNOS uncoupling IEA Caenorhabditis elegans 29108 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 29108 R-CEL-1602368 https://reactome.org/PathwayBrowser/#/R-CEL-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Caenorhabditis elegans 29108 R-CEL-1602374 https://reactome.org/PathwayBrowser/#/R-CEL-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Caenorhabditis elegans 29108 R-CEL-1602377 https://reactome.org/PathwayBrowser/#/R-CEL-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Caenorhabditis elegans 29108 R-CEL-1602398 https://reactome.org/PathwayBrowser/#/R-CEL-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Caenorhabditis elegans 29108 R-CEL-1602417 https://reactome.org/PathwayBrowser/#/R-CEL-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Caenorhabditis elegans 29108 R-CEL-1602446 https://reactome.org/PathwayBrowser/#/R-CEL-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Caenorhabditis elegans 29108 R-CEL-1606789 https://reactome.org/PathwayBrowser/#/R-CEL-1606789 ARSB hydrolyses DS IEA Caenorhabditis elegans 29108 R-CEL-1793207 https://reactome.org/PathwayBrowser/#/R-CEL-1793207 ARSB hydrolyses C4S/C6S chains IEA Caenorhabditis elegans 29108 R-CEL-1855153 https://reactome.org/PathwayBrowser/#/R-CEL-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Caenorhabditis elegans 29108 R-CEL-1855177 https://reactome.org/PathwayBrowser/#/R-CEL-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Caenorhabditis elegans 29108 R-CEL-1855214 https://reactome.org/PathwayBrowser/#/R-CEL-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Caenorhabditis elegans 29108 R-CEL-1855221 https://reactome.org/PathwayBrowser/#/R-CEL-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Caenorhabditis elegans 29108 R-CEL-202111 https://reactome.org/PathwayBrowser/#/R-CEL-202111 AKT1 phosphorylates eNOS IEA Caenorhabditis elegans 29108 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 29108 R-CEL-2089943 https://reactome.org/PathwayBrowser/#/R-CEL-2089943 TRPC1 translocates calcium from the extracellular region to the cytosol IEA Caenorhabditis elegans 29108 R-CEL-210420 https://reactome.org/PathwayBrowser/#/R-CEL-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Caenorhabditis elegans 29108 R-CEL-210430 https://reactome.org/PathwayBrowser/#/R-CEL-210430 Release of L-Glutamate at the synapse IEA Caenorhabditis elegans 29108 R-CEL-2160892 https://reactome.org/PathwayBrowser/#/R-CEL-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Caenorhabditis elegans 29108 R-CEL-2424243 https://reactome.org/PathwayBrowser/#/R-CEL-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Caenorhabditis elegans 29108 R-CEL-2514867 https://reactome.org/PathwayBrowser/#/R-CEL-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Caenorhabditis elegans 29108 R-CEL-2581474 https://reactome.org/PathwayBrowser/#/R-CEL-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Caenorhabditis elegans 29108 R-CEL-265645 https://reactome.org/PathwayBrowser/#/R-CEL-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Caenorhabditis elegans 29108 R-CEL-2684901 https://reactome.org/PathwayBrowser/#/R-CEL-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Caenorhabditis elegans 29108 R-CEL-2730867 https://reactome.org/PathwayBrowser/#/R-CEL-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Caenorhabditis elegans 29108 R-CEL-2730872 https://reactome.org/PathwayBrowser/#/R-CEL-2730872 Activation of Calcineurin IEA Caenorhabditis elegans 29108 R-CEL-2744242 https://reactome.org/PathwayBrowser/#/R-CEL-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Caenorhabditis elegans 29108 R-CEL-3229181 https://reactome.org/PathwayBrowser/#/R-CEL-3229181 CALM1:Ca2+ binds CNG channel IEA Caenorhabditis elegans 29108 R-CEL-3295579 https://reactome.org/PathwayBrowser/#/R-CEL-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Caenorhabditis elegans 29108 R-CEL-354066 https://reactome.org/PathwayBrowser/#/R-CEL-354066 Translocation of PTK2 to Focal complexes IEA Caenorhabditis elegans 29108 R-CEL-354073 https://reactome.org/PathwayBrowser/#/R-CEL-354073 Autophosphorylation of PTK2 at Y397 IEA Caenorhabditis elegans 29108 R-CEL-354087 https://reactome.org/PathwayBrowser/#/R-CEL-354087 Recruitment of GRB2 to p-PTK2 IEA Caenorhabditis elegans 29108 R-CEL-354124 https://reactome.org/PathwayBrowser/#/R-CEL-354124 Phosphorylation of pPTK2 by SRC IEA Caenorhabditis elegans 29108 R-CEL-354149 https://reactome.org/PathwayBrowser/#/R-CEL-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Caenorhabditis elegans 29108 R-CEL-354165 https://reactome.org/PathwayBrowser/#/R-CEL-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Caenorhabditis elegans 29108 R-CEL-354173 https://reactome.org/PathwayBrowser/#/R-CEL-354173 Activation of Rap1 by cytosolic GEFs IEA Caenorhabditis elegans 29108 R-CEL-372448 https://reactome.org/PathwayBrowser/#/R-CEL-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Caenorhabditis elegans 29108 R-CEL-377640 https://reactome.org/PathwayBrowser/#/R-CEL-377640 Autophosphorylation of SRC IEA Caenorhabditis elegans 29108 R-CEL-377641 https://reactome.org/PathwayBrowser/#/R-CEL-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Caenorhabditis elegans 29108 R-CEL-377644 https://reactome.org/PathwayBrowser/#/R-CEL-377644 Release of CSK from SRC IEA Caenorhabditis elegans 29108 R-CEL-399712 https://reactome.org/PathwayBrowser/#/R-CEL-399712 Activation of Ca permeable AMPA receptors IEA Caenorhabditis elegans 29108 R-CEL-418309 https://reactome.org/PathwayBrowser/#/R-CEL-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Caenorhabditis elegans 29108 R-CEL-418365 https://reactome.org/PathwayBrowser/#/R-CEL-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Caenorhabditis elegans 29108 R-CEL-425661 https://reactome.org/PathwayBrowser/#/R-CEL-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Caenorhabditis elegans 29108 R-CEL-425678 https://reactome.org/PathwayBrowser/#/R-CEL-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Caenorhabditis elegans 29108 R-CEL-425822 https://reactome.org/PathwayBrowser/#/R-CEL-425822 K+-independent Li+/Ca2+ exchanger transport IEA Caenorhabditis elegans 29108 R-CEL-426223 https://reactome.org/PathwayBrowser/#/R-CEL-426223 Cation influx mediated by TRPC3/6/7 IEA Caenorhabditis elegans 29108 R-CEL-427910 https://reactome.org/PathwayBrowser/#/R-CEL-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Caenorhabditis elegans 29108 R-CEL-429415 https://reactome.org/PathwayBrowser/#/R-CEL-429415 SYK binds to integrin alphaIIb beta3 IEA Caenorhabditis elegans 29108 R-CEL-429441 https://reactome.org/PathwayBrowser/#/R-CEL-429441 SYK activation by SRC IEA Caenorhabditis elegans 29108 R-CEL-432164 https://reactome.org/PathwayBrowser/#/R-CEL-432164 Ca2+ influx into the post-synaptic cell IEA Caenorhabditis elegans 29108 R-CEL-4332358 https://reactome.org/PathwayBrowser/#/R-CEL-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Caenorhabditis elegans 29108 R-CEL-4332359 https://reactome.org/PathwayBrowser/#/R-CEL-4332359 Active calmodulin binds CAMK2 IEA Caenorhabditis elegans 29108 R-CEL-4332363 https://reactome.org/PathwayBrowser/#/R-CEL-4332363 Autophosphorylation and activation of CAMK2 IEA Caenorhabditis elegans 29108 R-CEL-438037 https://reactome.org/PathwayBrowser/#/R-CEL-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Caenorhabditis elegans 29108 R-CEL-442749 https://reactome.org/PathwayBrowser/#/R-CEL-442749 CaMKK autophosphorylates in the nucleus IEA Caenorhabditis elegans 29108 R-CEL-445699 https://reactome.org/PathwayBrowser/#/R-CEL-445699 ATP Hydrolysis By Myosin IEA Caenorhabditis elegans 29108 R-CEL-445700 https://reactome.org/PathwayBrowser/#/R-CEL-445700 Myosin Binds ATP IEA Caenorhabditis elegans 29108 R-CEL-445704 https://reactome.org/PathwayBrowser/#/R-CEL-445704 Calcium Binds Caldesmon IEA Caenorhabditis elegans 29108 R-CEL-445705 https://reactome.org/PathwayBrowser/#/R-CEL-445705 Release Of ADP From Myosin IEA Caenorhabditis elegans 29108 R-CEL-451311 https://reactome.org/PathwayBrowser/#/R-CEL-451311 Activation of Ca-permeable Kainate receptors IEA Caenorhabditis elegans 29108 R-CEL-4551465 https://reactome.org/PathwayBrowser/#/R-CEL-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Caenorhabditis elegans 29108 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 29108 R-CEL-5138432 https://reactome.org/PathwayBrowser/#/R-CEL-5138432 DVL2 is phosphorylated by PKC IEA Caenorhabditis elegans 29108 R-CEL-5218813 https://reactome.org/PathwayBrowser/#/R-CEL-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Caenorhabditis elegans 29108 R-CEL-5218823 https://reactome.org/PathwayBrowser/#/R-CEL-5218823 PKC phosphorylates sphingosine kinase 1 IEA Caenorhabditis elegans 29108 R-CEL-5223304 https://reactome.org/PathwayBrowser/#/R-CEL-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Caenorhabditis elegans 29108 R-CEL-5577213 https://reactome.org/PathwayBrowser/#/R-CEL-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Caenorhabditis elegans 29108 R-CEL-5626507 https://reactome.org/PathwayBrowser/#/R-CEL-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Caenorhabditis elegans 29108 R-CEL-5626549 https://reactome.org/PathwayBrowser/#/R-CEL-5626549 IQGAPs bind CALM1 IEA Caenorhabditis elegans 29108 R-CEL-5672972 https://reactome.org/PathwayBrowser/#/R-CEL-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Caenorhabditis elegans 29108 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 29108 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 29108 R-CEL-5672980 https://reactome.org/PathwayBrowser/#/R-CEL-5672980 Dissociation of RAS:RAF complex IEA Caenorhabditis elegans 29108 R-CEL-5694018 https://reactome.org/PathwayBrowser/#/R-CEL-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Caenorhabditis elegans 29108 R-CEL-622326 https://reactome.org/PathwayBrowser/#/R-CEL-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Caenorhabditis elegans 29108 R-CEL-629595 https://reactome.org/PathwayBrowser/#/R-CEL-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 29108 R-CEL-71181 https://reactome.org/PathwayBrowser/#/R-CEL-71181 FAH cleaves 4FAA IEA Caenorhabditis elegans 29108 R-CEL-71401 https://reactome.org/PathwayBrowser/#/R-CEL-71401 OGDH dimer decarboxylates 2-OG IEA Caenorhabditis elegans 29108 R-CEL-71541 https://reactome.org/PathwayBrowser/#/R-CEL-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Caenorhabditis elegans 29108 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 29108 R-CEL-74948 https://reactome.org/PathwayBrowser/#/R-CEL-74948 PP2A dephosphorylates p-RHO to RHO IEA Caenorhabditis elegans 29108 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 29108 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 29108 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 29108 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 29108 R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 29108 R-CEL-8857662 https://reactome.org/PathwayBrowser/#/R-CEL-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Caenorhabditis elegans 29108 R-CEL-8862771 https://reactome.org/PathwayBrowser/#/R-CEL-8862771 PLA2G2A binds bacterial phospholipids IEA Caenorhabditis elegans 29108 R-CEL-888589 https://reactome.org/PathwayBrowser/#/R-CEL-888589 Release of GABA at the synapse IEA Caenorhabditis elegans 29108 R-CEL-8932633 https://reactome.org/PathwayBrowser/#/R-CEL-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Caenorhabditis elegans 29108 R-CEL-8949178 https://reactome.org/PathwayBrowser/#/R-CEL-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Caenorhabditis elegans 29108 R-CEL-8949688 https://reactome.org/PathwayBrowser/#/R-CEL-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Caenorhabditis elegans 29108 R-CEL-936883 https://reactome.org/PathwayBrowser/#/R-CEL-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Caenorhabditis elegans 29108 R-CEL-9619355 https://reactome.org/PathwayBrowser/#/R-CEL-9619355 CaMKK autophosphorylates in the cytosol IEA Caenorhabditis elegans 29108 R-CEL-9619376 https://reactome.org/PathwayBrowser/#/R-CEL-9619376 CAMK1 binds calmodulin IEA Caenorhabditis elegans 29108 R-CEL-9648983 https://reactome.org/PathwayBrowser/#/R-CEL-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Caenorhabditis elegans 29108 R-CEL-9653585 https://reactome.org/PathwayBrowser/#/R-CEL-9653585 S-Farn-Me KRAS4B binds calmodulin IEA Caenorhabditis elegans 29108 R-CEL-9654521 https://reactome.org/PathwayBrowser/#/R-CEL-9654521 Calmodulin dissociates KRAS4B from the plasma membrane IEA Caenorhabditis elegans 29108 R-CEL-9654523 https://reactome.org/PathwayBrowser/#/R-CEL-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Caenorhabditis elegans 29108 R-CEL-9654525 https://reactome.org/PathwayBrowser/#/R-CEL-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ IEA Caenorhabditis elegans 29108 R-CEL-9654533 https://reactome.org/PathwayBrowser/#/R-CEL-9654533 KRAS4B recycles to the plasma membrane IEA Caenorhabditis elegans 29108 R-CEL-9657599 https://reactome.org/PathwayBrowser/#/R-CEL-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Caenorhabditis elegans 29108 R-CEL-9657603 https://reactome.org/PathwayBrowser/#/R-CEL-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Caenorhabditis elegans 29108 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 29108 R-CEL-9657608 https://reactome.org/PathwayBrowser/#/R-CEL-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Caenorhabditis elegans 29108 R-CEL-9701141 https://reactome.org/PathwayBrowser/#/R-CEL-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Caenorhabditis elegans 29108 R-CEL-9717215 https://reactome.org/PathwayBrowser/#/R-CEL-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Caenorhabditis elegans 29108 R-CEL-975311 https://reactome.org/PathwayBrowser/#/R-CEL-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Caenorhabditis elegans 29108 R-CEL-9756177 https://reactome.org/PathwayBrowser/#/R-CEL-9756177 PON1,3 hydrolyse ATVL to ATV IEA Caenorhabditis elegans 29108 R-CEL-9853499 https://reactome.org/PathwayBrowser/#/R-CEL-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 29108 R-CEL-9853512 https://reactome.org/PathwayBrowser/#/R-CEL-9853512 DLST transfers succinyl to CoA IEA Caenorhabditis elegans 29108 R-CFA-111881 https://reactome.org/PathwayBrowser/#/R-CFA-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Canis familiaris 29108 R-CFA-111883 https://reactome.org/PathwayBrowser/#/R-CFA-111883 Hydrolysis of phosphatidylcholine IEA Canis familiaris 29108 R-CFA-111930 https://reactome.org/PathwayBrowser/#/R-CFA-111930 Adenylate cyclase produces cAMP IEA Canis familiaris 29108 R-CFA-111956 https://reactome.org/PathwayBrowser/#/R-CFA-111956 Calmodulin activates Cam-PDE 1 IEA Canis familiaris 29108 R-CFA-111966 https://reactome.org/PathwayBrowser/#/R-CFA-111966 GRK2 binds CALM1:4Ca2+ IEA Canis familiaris 29108 R-CFA-111970 https://reactome.org/PathwayBrowser/#/R-CFA-111970 PKC phosphorylates GRK2 IEA Canis familiaris 29108 R-CFA-114553 https://reactome.org/PathwayBrowser/#/R-CFA-114553 Activation of conventional Protein Kinase C IEA Canis familiaris 29108 R-CFA-114683 https://reactome.org/PathwayBrowser/#/R-CFA-114683 Phosphorylation of Platelet Sec-1 IEA Canis familiaris 29108 R-CFA-114684 https://reactome.org/PathwayBrowser/#/R-CFA-114684 Phosphorylation of Syntaxin-4 IEA Canis familiaris 29108 R-CFA-114697 https://reactome.org/PathwayBrowser/#/R-CFA-114697 Activated thrombin (factor IIa) cleaves PAR3,4, activating them IEA Canis familiaris 29108 R-CFA-1168373 https://reactome.org/PathwayBrowser/#/R-CFA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Canis familiaris 29108 R-CFA-1168376 https://reactome.org/PathwayBrowser/#/R-CFA-1168376 STIM1 oligomerizes IEA Canis familiaris 29108 R-CFA-1168635 https://reactome.org/PathwayBrowser/#/R-CFA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Canis familiaris 29108 R-CFA-1183128 https://reactome.org/PathwayBrowser/#/R-CFA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Canis familiaris 29108 R-CFA-139854 https://reactome.org/PathwayBrowser/#/R-CFA-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Canis familiaris 29108 R-CFA-139855 https://reactome.org/PathwayBrowser/#/R-CFA-139855 P2X1-mediated entry of Ca++ from plasma IEA Canis familiaris 29108 R-CFA-139941 https://reactome.org/PathwayBrowser/#/R-CFA-139941 Binding of IP3 to IP3 receptor IEA Canis familiaris 29108 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 29108 R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 29108 R-CFA-140686 https://reactome.org/PathwayBrowser/#/R-CFA-140686 factor Va + factor Xa -> Va:Xa complex (prothrombinase) IEA Canis familiaris 29108 R-CFA-140696 https://reactome.org/PathwayBrowser/#/R-CFA-140696 factor V -> factor Va + factor V activation peptide IEA Canis familiaris 29108 R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 29108 R-CFA-140736 https://reactome.org/PathwayBrowser/#/R-CFA-140736 factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) IEA Canis familiaris 29108 R-CFA-140748 https://reactome.org/PathwayBrowser/#/R-CFA-140748 tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex IEA Canis familiaris 29108 R-CFA-140769 https://reactome.org/PathwayBrowser/#/R-CFA-140769 factor VII -> factor VIIa IEA Canis familiaris 29108 R-CFA-140777 https://reactome.org/PathwayBrowser/#/R-CFA-140777 factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) IEA Canis familiaris 29108 R-CFA-140783 https://reactome.org/PathwayBrowser/#/R-CFA-140783 tissue factor (TF) + factor VII (F7) -> TF:F7 complex IEA Canis familiaris 29108 R-CFA-140791 https://reactome.org/PathwayBrowser/#/R-CFA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Canis familiaris 29108 R-CFA-140823 https://reactome.org/PathwayBrowser/#/R-CFA-140823 factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) IEA Canis familiaris 29108 R-CFA-140825 https://reactome.org/PathwayBrowser/#/R-CFA-140825 TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa IEA Canis familiaris 29108 R-CFA-140847 https://reactome.org/PathwayBrowser/#/R-CFA-140847 factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain IEA Canis familiaris 29108 R-CFA-140870 https://reactome.org/PathwayBrowser/#/R-CFA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Canis familiaris 29108 R-CFA-140872 https://reactome.org/PathwayBrowser/#/R-CFA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Canis familiaris 29108 R-CFA-141026 https://reactome.org/PathwayBrowser/#/R-CFA-141026 Activated protein C cleaves factor Va to factor Vi intermediate form IEA Canis familiaris 29108 R-CFA-141040 https://reactome.org/PathwayBrowser/#/R-CFA-141040 Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C IEA Canis familiaris 29108 R-CFA-141046 https://reactome.org/PathwayBrowser/#/R-CFA-141046 activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin IEA Canis familiaris 29108 R-CFA-1482604 https://reactome.org/PathwayBrowser/#/R-CFA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Canis familiaris 29108 R-CFA-1482612 https://reactome.org/PathwayBrowser/#/R-CFA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 29108 R-CFA-1482656 https://reactome.org/PathwayBrowser/#/R-CFA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Canis familiaris 29108 R-CFA-1482685 https://reactome.org/PathwayBrowser/#/R-CFA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 29108 R-CFA-1482759 https://reactome.org/PathwayBrowser/#/R-CFA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Canis familiaris 29108 R-CFA-1482771 https://reactome.org/PathwayBrowser/#/R-CFA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Canis familiaris 29108 R-CFA-1482825 https://reactome.org/PathwayBrowser/#/R-CFA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Canis familiaris 29108 R-CFA-1482828 https://reactome.org/PathwayBrowser/#/R-CFA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Canis familiaris 29108 R-CFA-1482856 https://reactome.org/PathwayBrowser/#/R-CFA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Canis familiaris 29108 R-CFA-1482862 https://reactome.org/PathwayBrowser/#/R-CFA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Canis familiaris 29108 R-CFA-1482884 https://reactome.org/PathwayBrowser/#/R-CFA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Canis familiaris 29108 R-CFA-1482897 https://reactome.org/PathwayBrowser/#/R-CFA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Canis familiaris 29108 R-CFA-1482900 https://reactome.org/PathwayBrowser/#/R-CFA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Canis familiaris 29108 R-CFA-1602368 https://reactome.org/PathwayBrowser/#/R-CFA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Canis familiaris 29108 R-CFA-1602374 https://reactome.org/PathwayBrowser/#/R-CFA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Canis familiaris 29108 R-CFA-1602377 https://reactome.org/PathwayBrowser/#/R-CFA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Canis familiaris 29108 R-CFA-1602398 https://reactome.org/PathwayBrowser/#/R-CFA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Canis familiaris 29108 R-CFA-1602417 https://reactome.org/PathwayBrowser/#/R-CFA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Canis familiaris 29108 R-CFA-1602446 https://reactome.org/PathwayBrowser/#/R-CFA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Canis familiaris 29108 R-CFA-1606789 https://reactome.org/PathwayBrowser/#/R-CFA-1606789 ARSB hydrolyses DS IEA Canis familiaris 29108 R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 29108 R-CFA-1606839 https://reactome.org/PathwayBrowser/#/R-CFA-1606839 ARSC hydrolyzes steroid sulfates IEA Canis familiaris 29108 R-CFA-1614362 https://reactome.org/PathwayBrowser/#/R-CFA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Canis familiaris 29108 R-CFA-166726 https://reactome.org/PathwayBrowser/#/R-CFA-166726 Activation of MASPs IEA Canis familiaris 29108 R-CFA-166753 https://reactome.org/PathwayBrowser/#/R-CFA-166753 Conversion of C4 into C4a and C4b IEA Canis familiaris 29108 R-CFA-166792 https://reactome.org/PathwayBrowser/#/R-CFA-166792 Conversion of C2 into C2a and C2b IEA Canis familiaris 29108 R-CFA-1675928 https://reactome.org/PathwayBrowser/#/R-CFA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Canis familiaris 29108 R-CFA-1675939 https://reactome.org/PathwayBrowser/#/R-CFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Canis familiaris 29108 R-CFA-1675961 https://reactome.org/PathwayBrowser/#/R-CFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Canis familiaris 29108 R-CFA-1676024 https://reactome.org/PathwayBrowser/#/R-CFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Canis familiaris 29108 R-CFA-1676109 https://reactome.org/PathwayBrowser/#/R-CFA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Canis familiaris 29108 R-CFA-1676206 https://reactome.org/PathwayBrowser/#/R-CFA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Canis familiaris 29108 R-CFA-1678650 https://reactome.org/PathwayBrowser/#/R-CFA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Canis familiaris 29108 R-CFA-173626 https://reactome.org/PathwayBrowser/#/R-CFA-173626 Activation of C1r IEA Canis familiaris 29108 R-CFA-1793182 https://reactome.org/PathwayBrowser/#/R-CFA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Canis familiaris 29108 R-CFA-1793207 https://reactome.org/PathwayBrowser/#/R-CFA-1793207 ARSB hydrolyses C4S/C6S chains IEA Canis familiaris 29108 R-CFA-1855153 https://reactome.org/PathwayBrowser/#/R-CFA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Canis familiaris 29108 R-CFA-1855177 https://reactome.org/PathwayBrowser/#/R-CFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Canis familiaris 29108 R-CFA-1855214 https://reactome.org/PathwayBrowser/#/R-CFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Canis familiaris 29108 R-CFA-1855221 https://reactome.org/PathwayBrowser/#/R-CFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Canis familiaris 29108 R-CFA-187020 https://reactome.org/PathwayBrowser/#/R-CFA-187020 Part of pro-beta-NGF is processed to mature beta-NGF IEA Canis familiaris 29108 R-CFA-2025890 https://reactome.org/PathwayBrowser/#/R-CFA-2025890 Calcineurin binds NFATC1,2,3 IEA Canis familiaris 29108 R-CFA-2089943 https://reactome.org/PathwayBrowser/#/R-CFA-2089943 TRPC1 translocates calcium from the extracellular region to the cytosol IEA Canis familiaris 29108 R-CFA-210420 https://reactome.org/PathwayBrowser/#/R-CFA-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Canis familiaris 29108 R-CFA-210430 https://reactome.org/PathwayBrowser/#/R-CFA-210430 Release of L-Glutamate at the synapse IEA Canis familiaris 29108 R-CFA-2160892 https://reactome.org/PathwayBrowser/#/R-CFA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Canis familiaris 29108 R-CFA-2161768 https://reactome.org/PathwayBrowser/#/R-CFA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Canis familiaris 29108 R-CFA-2161907 https://reactome.org/PathwayBrowser/#/R-CFA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Canis familiaris 29108 R-CFA-2161917 https://reactome.org/PathwayBrowser/#/R-CFA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Canis familiaris 29108 R-CFA-2248891 https://reactome.org/PathwayBrowser/#/R-CFA-2248891 M6PR transports activated ARSA to the lysosome IEA Canis familiaris 29108 R-CFA-2424243 https://reactome.org/PathwayBrowser/#/R-CFA-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Canis familiaris 29108 R-CFA-2514867 https://reactome.org/PathwayBrowser/#/R-CFA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Canis familiaris 29108 R-CFA-2534359 https://reactome.org/PathwayBrowser/#/R-CFA-2534359 CatSper Channel Mediated Calcium Transport IEA Canis familiaris 29108 R-CFA-2581474 https://reactome.org/PathwayBrowser/#/R-CFA-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Canis familiaris 29108 R-CFA-2586748 https://reactome.org/PathwayBrowser/#/R-CFA-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ IEA Canis familiaris 29108 R-CFA-264976 https://reactome.org/PathwayBrowser/#/R-CFA-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Canis familiaris 29108 R-CFA-265153 https://reactome.org/PathwayBrowser/#/R-CFA-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Canis familiaris 29108 R-CFA-265296 https://reactome.org/PathwayBrowser/#/R-CFA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Canis familiaris 29108 R-CFA-265301 https://reactome.org/PathwayBrowser/#/R-CFA-265301 Corticotropin cleavage from POMC IEA Canis familiaris 29108 R-CFA-265645 https://reactome.org/PathwayBrowser/#/R-CFA-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Canis familiaris 29108 R-CFA-266050 https://reactome.org/PathwayBrowser/#/R-CFA-266050 LTA4 is converted to LTC4 by LTC4S IEA Canis familiaris 29108 R-CFA-266051 https://reactome.org/PathwayBrowser/#/R-CFA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Canis familiaris 29108 R-CFA-2684901 https://reactome.org/PathwayBrowser/#/R-CFA-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Canis familiaris 29108 R-CFA-2685505 https://reactome.org/PathwayBrowser/#/R-CFA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Canis familiaris 29108 R-CFA-2730664 https://reactome.org/PathwayBrowser/#/R-CFA-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Canis familiaris 29108 R-CFA-2730849 https://reactome.org/PathwayBrowser/#/R-CFA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Canis familiaris 29108 R-CFA-2730867 https://reactome.org/PathwayBrowser/#/R-CFA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Canis familiaris 29108 R-CFA-2730872 https://reactome.org/PathwayBrowser/#/R-CFA-2730872 Activation of Calcineurin IEA Canis familiaris 29108 R-CFA-2744242 https://reactome.org/PathwayBrowser/#/R-CFA-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Canis familiaris 29108 R-CFA-2744361 https://reactome.org/PathwayBrowser/#/R-CFA-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Canis familiaris 29108 R-CFA-2855020 https://reactome.org/PathwayBrowser/#/R-CFA-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Canis familiaris 29108 R-CFA-2855054 https://reactome.org/PathwayBrowser/#/R-CFA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Canis familiaris 29108 R-CFA-2855125 https://reactome.org/PathwayBrowser/#/R-CFA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Canis familiaris 29108 R-CFA-3229181 https://reactome.org/PathwayBrowser/#/R-CFA-3229181 CALM1:Ca2+ binds CNG channel IEA Canis familiaris 29108 R-CFA-3295579 https://reactome.org/PathwayBrowser/#/R-CFA-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Canis familiaris 29108 R-CFA-354066 https://reactome.org/PathwayBrowser/#/R-CFA-354066 Translocation of PTK2 to Focal complexes IEA Canis familiaris 29108 R-CFA-354073 https://reactome.org/PathwayBrowser/#/R-CFA-354073 Autophosphorylation of PTK2 at Y397 IEA Canis familiaris 29108 R-CFA-354087 https://reactome.org/PathwayBrowser/#/R-CFA-354087 Recruitment of GRB2 to p-PTK2 IEA Canis familiaris 29108 R-CFA-354124 https://reactome.org/PathwayBrowser/#/R-CFA-354124 Phosphorylation of pPTK2 by SRC IEA Canis familiaris 29108 R-CFA-354149 https://reactome.org/PathwayBrowser/#/R-CFA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Canis familiaris 29108 R-CFA-354165 https://reactome.org/PathwayBrowser/#/R-CFA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Canis familiaris 29108 R-CFA-354173 https://reactome.org/PathwayBrowser/#/R-CFA-354173 Activation of Rap1 by cytosolic GEFs IEA Canis familiaris 29108 R-CFA-372448 https://reactome.org/PathwayBrowser/#/R-CFA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Canis familiaris 29108 R-CFA-372693 https://reactome.org/PathwayBrowser/#/R-CFA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Canis familiaris 29108 R-CFA-372697 https://reactome.org/PathwayBrowser/#/R-CFA-372697 Crk binding to p130cas IEA Canis familiaris 29108 R-CFA-372705 https://reactome.org/PathwayBrowser/#/R-CFA-372705 Recruitment of BCAR1 to PTK2 complex IEA Canis familiaris 29108 R-CFA-377640 https://reactome.org/PathwayBrowser/#/R-CFA-377640 Autophosphorylation of SRC IEA Canis familiaris 29108 R-CFA-377641 https://reactome.org/PathwayBrowser/#/R-CFA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Canis familiaris 29108 R-CFA-377643 https://reactome.org/PathwayBrowser/#/R-CFA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Canis familiaris 29108 R-CFA-377644 https://reactome.org/PathwayBrowser/#/R-CFA-377644 Release of CSK from SRC IEA Canis familiaris 29108 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 29108 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 29108 R-CFA-3827958 https://reactome.org/PathwayBrowser/#/R-CFA-3827958 E-cadherin degradation by MMP9, KLK7 IEA Canis familiaris 29108 R-CFA-389463 https://reactome.org/PathwayBrowser/#/R-CFA-389463 Proteinase-activated receptors can bind thrombin IEA Canis familiaris 29108 R-CFA-390593 https://reactome.org/PathwayBrowser/#/R-CFA-390593 ATP Hydrolysis By Myosin IEA Canis familiaris 29108 R-CFA-390595 https://reactome.org/PathwayBrowser/#/R-CFA-390595 Calcium Binds Troponin-C IEA Canis familiaris 29108 R-CFA-390597 https://reactome.org/PathwayBrowser/#/R-CFA-390597 Release Of ADP From Myosin IEA Canis familiaris 29108 R-CFA-390598 https://reactome.org/PathwayBrowser/#/R-CFA-390598 Myosin Binds ATP IEA Canis familiaris 29108 R-CFA-399712 https://reactome.org/PathwayBrowser/#/R-CFA-399712 Activation of Ca permeable AMPA receptors IEA Canis familiaris 29108 R-CFA-416639 https://reactome.org/PathwayBrowser/#/R-CFA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Canis familiaris 29108 R-CFA-418309 https://reactome.org/PathwayBrowser/#/R-CFA-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Canis familiaris 29108 R-CFA-418365 https://reactome.org/PathwayBrowser/#/R-CFA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Canis familiaris 29108 R-CFA-419001 https://reactome.org/PathwayBrowser/#/R-CFA-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Canis familiaris 29108 R-CFA-420724 https://reactome.org/PathwayBrowser/#/R-CFA-420724 CASR binds Ca2+ IEA Canis familiaris 29108 R-CFA-420739 https://reactome.org/PathwayBrowser/#/R-CFA-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Canis familiaris 29108 R-CFA-421007 https://reactome.org/PathwayBrowser/#/R-CFA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Canis familiaris 29108 R-CFA-422021 https://reactome.org/PathwayBrowser/#/R-CFA-422021 PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin IEA Canis familiaris 29108 R-CFA-4224014 https://reactome.org/PathwayBrowser/#/R-CFA-4224014 E-cadherin degradation by ADAM10, ADAM15 IEA Canis familiaris 29108 R-CFA-425661 https://reactome.org/PathwayBrowser/#/R-CFA-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Canis familiaris 29108 R-CFA-425678 https://reactome.org/PathwayBrowser/#/R-CFA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Canis familiaris 29108 R-CFA-425822 https://reactome.org/PathwayBrowser/#/R-CFA-425822 K+-independent Li+/Ca2+ exchanger transport IEA Canis familiaris 29108 R-CFA-426223 https://reactome.org/PathwayBrowser/#/R-CFA-426223 Cation influx mediated by TRPC3/6/7 IEA Canis familiaris 29108 R-CFA-427910 https://reactome.org/PathwayBrowser/#/R-CFA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Canis familiaris 29108 R-CFA-428262 https://reactome.org/PathwayBrowser/#/R-CFA-428262 ACER3 hydrolyzes phytoceramide IEA Canis familiaris 29108 R-CFA-429415 https://reactome.org/PathwayBrowser/#/R-CFA-429415 SYK binds to integrin alphaIIb beta3 IEA Canis familiaris 29108 R-CFA-429441 https://reactome.org/PathwayBrowser/#/R-CFA-429441 SYK activation by SRC IEA Canis familiaris 29108 R-CFA-432164 https://reactome.org/PathwayBrowser/#/R-CFA-432164 Ca2+ influx into the post-synaptic cell IEA Canis familiaris 29108 R-CFA-4332358 https://reactome.org/PathwayBrowser/#/R-CFA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Canis familiaris 29108 R-CFA-4332359 https://reactome.org/PathwayBrowser/#/R-CFA-4332359 Active calmodulin binds CAMK2 IEA Canis familiaris 29108 R-CFA-4332363 https://reactome.org/PathwayBrowser/#/R-CFA-4332363 Autophosphorylation and activation of CAMK2 IEA Canis familiaris 29108 R-CFA-438037 https://reactome.org/PathwayBrowser/#/R-CFA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Canis familiaris 29108 R-CFA-442749 https://reactome.org/PathwayBrowser/#/R-CFA-442749 CaMKK autophosphorylates in the nucleus IEA Canis familiaris 29108 R-CFA-445699 https://reactome.org/PathwayBrowser/#/R-CFA-445699 ATP Hydrolysis By Myosin IEA Canis familiaris 29108 R-CFA-445700 https://reactome.org/PathwayBrowser/#/R-CFA-445700 Myosin Binds ATP IEA Canis familiaris 29108 R-CFA-445704 https://reactome.org/PathwayBrowser/#/R-CFA-445704 Calcium Binds Caldesmon IEA Canis familiaris 29108 R-CFA-445705 https://reactome.org/PathwayBrowser/#/R-CFA-445705 Release Of ADP From Myosin IEA Canis familiaris 29108 R-CFA-445797 https://reactome.org/PathwayBrowser/#/R-CFA-445797 MYLK (MLCK) Active Calmodulin Binding IEA Canis familiaris 29108 R-CFA-445813 https://reactome.org/PathwayBrowser/#/R-CFA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Canis familiaris 29108 R-CFA-451311 https://reactome.org/PathwayBrowser/#/R-CFA-451311 Activation of Ca-permeable Kainate receptors IEA Canis familiaris 29108 R-CFA-4551451 https://reactome.org/PathwayBrowser/#/R-CFA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Canis familiaris 29108 R-CFA-4551465 https://reactome.org/PathwayBrowser/#/R-CFA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Canis familiaris 29108 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 29108 R-CFA-5138432 https://reactome.org/PathwayBrowser/#/R-CFA-5138432 DVL2 is phosphorylated by PKC IEA Canis familiaris 29108 R-CFA-5218813 https://reactome.org/PathwayBrowser/#/R-CFA-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Canis familiaris 29108 R-CFA-5218823 https://reactome.org/PathwayBrowser/#/R-CFA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Canis familiaris 29108 R-CFA-5223304 https://reactome.org/PathwayBrowser/#/R-CFA-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Canis familiaris 29108 R-CFA-5229194 https://reactome.org/PathwayBrowser/#/R-CFA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Canis familiaris 29108 R-CFA-5333671 https://reactome.org/PathwayBrowser/#/R-CFA-5333671 CLCAs self cleave IEA Canis familiaris 29108 R-CFA-5333678 https://reactome.org/PathwayBrowser/#/R-CFA-5333678 CPNEs bind PL IEA Canis familiaris 29108 R-CFA-5577213 https://reactome.org/PathwayBrowser/#/R-CFA-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Canis familiaris 29108 R-CFA-5578883 https://reactome.org/PathwayBrowser/#/R-CFA-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Canis familiaris 29108 R-CFA-5591040 https://reactome.org/PathwayBrowser/#/R-CFA-5591040 Activated protein C cleaves Factor Va intermediate form for Factor Va IEA Canis familiaris 29108 R-CFA-5591052 https://reactome.org/PathwayBrowser/#/R-CFA-5591052 PROCR binds Protein C IEA Canis familiaris 29108 R-CFA-5591086 https://reactome.org/PathwayBrowser/#/R-CFA-5591086 SERPINA5 binds activated protein C IEA Canis familiaris 29108 R-CFA-5602080 https://reactome.org/PathwayBrowser/#/R-CFA-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Canis familiaris 29108 R-CFA-5603467 https://reactome.org/PathwayBrowser/#/R-CFA-5603467 Activated protein C is released from PROCR IEA Canis familiaris 29108 R-CFA-5604929 https://reactome.org/PathwayBrowser/#/R-CFA-5604929 Activated protein C binds Protein S IEA Canis familiaris 29108 R-CFA-5606996 https://reactome.org/PathwayBrowser/#/R-CFA-5606996 Soluble PROCR binds activated protein C IEA Canis familiaris 29108 R-CFA-5607058 https://reactome.org/PathwayBrowser/#/R-CFA-5607058 Activated protein C:PROCR binds F2R IEA Canis familiaris 29108 R-CFA-5626316 https://reactome.org/PathwayBrowser/#/R-CFA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Canis familiaris 29108 R-CFA-5626507 https://reactome.org/PathwayBrowser/#/R-CFA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Canis familiaris 29108 R-CFA-5626549 https://reactome.org/PathwayBrowser/#/R-CFA-5626549 IQGAPs bind CALM1 IEA Canis familiaris 29108 R-CFA-5668629 https://reactome.org/PathwayBrowser/#/R-CFA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Canis familiaris 29108 R-CFA-5672965 https://reactome.org/PathwayBrowser/#/R-CFA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Canis familiaris 29108 R-CFA-5672969 https://reactome.org/PathwayBrowser/#/R-CFA-5672969 Phosphorylation of RAF IEA Canis familiaris 29108 R-CFA-5672972 https://reactome.org/PathwayBrowser/#/R-CFA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Canis familiaris 29108 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 29108 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 29108 R-CFA-5672980 https://reactome.org/PathwayBrowser/#/R-CFA-5672980 Dissociation of RAS:RAF complex IEA Canis familiaris 29108 R-CFA-5694018 https://reactome.org/PathwayBrowser/#/R-CFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Canis familiaris 29108 R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 29108 R-CFA-622326 https://reactome.org/PathwayBrowser/#/R-CFA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Canis familiaris 29108 R-CFA-629595 https://reactome.org/PathwayBrowser/#/R-CFA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 29108 R-CFA-6798474 https://reactome.org/PathwayBrowser/#/R-CFA-6798474 S100A8:S100A9 binds Zn2+ IEA Canis familiaris 29108 R-CFA-6798528 https://reactome.org/PathwayBrowser/#/R-CFA-6798528 S100A8:S100A9 binds Mn2+ IEA Canis familiaris 29108 R-CFA-6805943 https://reactome.org/PathwayBrowser/#/R-CFA-6805943 S100A1 binds TLR4:LY96 IEA Canis familiaris 29108 R-CFA-71181 https://reactome.org/PathwayBrowser/#/R-CFA-71181 FAH cleaves 4FAA IEA Canis familiaris 29108 R-CFA-71401 https://reactome.org/PathwayBrowser/#/R-CFA-71401 OGDH dimer decarboxylates 2-OG IEA Canis familiaris 29108 R-CFA-71541 https://reactome.org/PathwayBrowser/#/R-CFA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Canis familiaris 29108 R-CFA-71588 https://reactome.org/PathwayBrowser/#/R-CFA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Canis familiaris 29108 R-CFA-74885 https://reactome.org/PathwayBrowser/#/R-CFA-74885 GUCYs converts GTP to cGMP IEA Canis familiaris 29108 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 29108 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 29108 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 29108 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 29108 R-CFA-74948 https://reactome.org/PathwayBrowser/#/R-CFA-74948 PP2A dephosphorylates p-RHO to RHO IEA Canis familiaris 29108 R-CFA-8848658 https://reactome.org/PathwayBrowser/#/R-CFA-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Canis familiaris 29108 R-CFA-8850846 https://reactome.org/PathwayBrowser/#/R-CFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Canis familiaris 29108 R-CFA-8850854 https://reactome.org/PathwayBrowser/#/R-CFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Canis familiaris 29108 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 29108 R-CFA-8851110 https://reactome.org/PathwayBrowser/#/R-CFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Canis familiaris 29108 R-CFA-8851129 https://reactome.org/PathwayBrowser/#/R-CFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Canis familiaris 29108 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 29108 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 29108 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 29108 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 29108 R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 29108 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 29108 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 29108 R-CFA-8852509 https://reactome.org/PathwayBrowser/#/R-CFA-8852509 CL-LK binds carbohydrates on target cell surface IEA Canis familiaris 29108 R-CFA-8852716 https://reactome.org/PathwayBrowser/#/R-CFA-8852716 Thrombin, ELANE cleave C5 IEA Canis familiaris 29108 R-CFA-8857662 https://reactome.org/PathwayBrowser/#/R-CFA-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Canis familiaris 29108 R-CFA-8878787 https://reactome.org/PathwayBrowser/#/R-CFA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Canis familiaris 29108 R-CFA-888589 https://reactome.org/PathwayBrowser/#/R-CFA-888589 Release of GABA at the synapse IEA Canis familiaris 29108 R-CFA-8932633 https://reactome.org/PathwayBrowser/#/R-CFA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Canis familiaris 29108 R-CFA-8934446 https://reactome.org/PathwayBrowser/#/R-CFA-8934446 Activated PKC phosphorylates SHC1 IEA Canis familiaris 29108 R-CFA-8934819 https://reactome.org/PathwayBrowser/#/R-CFA-8934819 Cytoplasmic proteases cleave Profilaggrin producing Filaggrin IEA Canis familiaris 29108 R-CFA-8949178 https://reactome.org/PathwayBrowser/#/R-CFA-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Canis familiaris 29108 R-CFA-8949688 https://reactome.org/PathwayBrowser/#/R-CFA-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Canis familiaris 29108 R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 29108 R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 29108 R-CFA-9015379 https://reactome.org/PathwayBrowser/#/R-CFA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Canis familiaris 29108 R-CFA-936883 https://reactome.org/PathwayBrowser/#/R-CFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Canis familiaris 29108 R-CFA-9603302 https://reactome.org/PathwayBrowser/#/R-CFA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Canis familiaris 29108 R-CFA-9619355 https://reactome.org/PathwayBrowser/#/R-CFA-9619355 CaMKK autophosphorylates in the cytosol IEA Canis familiaris 29108 R-CFA-9619376 https://reactome.org/PathwayBrowser/#/R-CFA-9619376 CAMK1 binds calmodulin IEA Canis familiaris 29108 R-CFA-9626848 https://reactome.org/PathwayBrowser/#/R-CFA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Canis familiaris 29108 R-CFA-9648983 https://reactome.org/PathwayBrowser/#/R-CFA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Canis familiaris 29108 R-CFA-9653585 https://reactome.org/PathwayBrowser/#/R-CFA-9653585 S-Farn-Me KRAS4B binds calmodulin IEA Canis familiaris 29108 R-CFA-9654521 https://reactome.org/PathwayBrowser/#/R-CFA-9654521 Calmodulin dissociates KRAS4B from the plasma membrane IEA Canis familiaris 29108 R-CFA-9654523 https://reactome.org/PathwayBrowser/#/R-CFA-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Canis familiaris 29108 R-CFA-9654525 https://reactome.org/PathwayBrowser/#/R-CFA-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ IEA Canis familiaris 29108 R-CFA-9654533 https://reactome.org/PathwayBrowser/#/R-CFA-9654533 KRAS4B recycles to the plasma membrane IEA Canis familiaris 29108 R-CFA-9657599 https://reactome.org/PathwayBrowser/#/R-CFA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Canis familiaris 29108 R-CFA-9657603 https://reactome.org/PathwayBrowser/#/R-CFA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Canis familiaris 29108 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 29108 R-CFA-9657608 https://reactome.org/PathwayBrowser/#/R-CFA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Canis familiaris 29108 R-CFA-9659568 https://reactome.org/PathwayBrowser/#/R-CFA-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Canis familiaris 29108 R-CFA-9701055 https://reactome.org/PathwayBrowser/#/R-CFA-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Canis familiaris 29108 R-CFA-9701141 https://reactome.org/PathwayBrowser/#/R-CFA-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Canis familiaris 29108 R-CFA-9707186 https://reactome.org/PathwayBrowser/#/R-CFA-9707186 ALOX5 binds ALOX5 inhibitors IEA Canis familiaris 29108 R-CFA-9708859 https://reactome.org/PathwayBrowser/#/R-CFA-9708859 Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it IEA Canis familiaris 29108 R-CFA-9717215 https://reactome.org/PathwayBrowser/#/R-CFA-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Canis familiaris 29108 R-CFA-975311 https://reactome.org/PathwayBrowser/#/R-CFA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Canis familiaris 29108 R-CFA-9756177 https://reactome.org/PathwayBrowser/#/R-CFA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Canis familiaris 29108 R-CFA-9840949 https://reactome.org/PathwayBrowser/#/R-CFA-9840949 ARSA removes sulfate from SM3 IEA Canis familiaris 29108 R-CFA-9853499 https://reactome.org/PathwayBrowser/#/R-CFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 29108 R-CFA-9853512 https://reactome.org/PathwayBrowser/#/R-CFA-9853512 DLST transfers succinyl to CoA IEA Canis familiaris 29108 R-DDI-111915 https://reactome.org/PathwayBrowser/#/R-DDI-111915 CAMK4 autophosphorylates IEA Dictyostelium discoideum 29108 R-DDI-111930 https://reactome.org/PathwayBrowser/#/R-DDI-111930 Adenylate cyclase produces cAMP IEA Dictyostelium discoideum 29108 R-DDI-111956 https://reactome.org/PathwayBrowser/#/R-DDI-111956 Calmodulin activates Cam-PDE 1 IEA Dictyostelium discoideum 29108 R-DDI-114553 https://reactome.org/PathwayBrowser/#/R-DDI-114553 Activation of conventional Protein Kinase C IEA Dictyostelium discoideum 29108 R-DDI-114683 https://reactome.org/PathwayBrowser/#/R-DDI-114683 Phosphorylation of Platelet Sec-1 IEA Dictyostelium discoideum 29108 R-DDI-114684 https://reactome.org/PathwayBrowser/#/R-DDI-114684 Phosphorylation of Syntaxin-4 IEA Dictyostelium discoideum 29108 R-DDI-1168373 https://reactome.org/PathwayBrowser/#/R-DDI-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Dictyostelium discoideum 29108 R-DDI-139854 https://reactome.org/PathwayBrowser/#/R-DDI-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Dictyostelium discoideum 29108 R-DDI-139855 https://reactome.org/PathwayBrowser/#/R-DDI-139855 P2X1-mediated entry of Ca++ from plasma IEA Dictyostelium discoideum 29108 R-DDI-139941 https://reactome.org/PathwayBrowser/#/R-DDI-139941 Binding of IP3 to IP3 receptor IEA Dictyostelium discoideum 29108 R-DDI-1497784 https://reactome.org/PathwayBrowser/#/R-DDI-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Dictyostelium discoideum 29108 R-DDI-1497796 https://reactome.org/PathwayBrowser/#/R-DDI-1497796 BH2 binding can lead to eNOS uncoupling IEA Dictyostelium discoideum 29108 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 29108 R-DDI-1675928 https://reactome.org/PathwayBrowser/#/R-DDI-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Dictyostelium discoideum 29108 R-DDI-1675939 https://reactome.org/PathwayBrowser/#/R-DDI-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Dictyostelium discoideum 29108 R-DDI-1675961 https://reactome.org/PathwayBrowser/#/R-DDI-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Dictyostelium discoideum 29108 R-DDI-1676024 https://reactome.org/PathwayBrowser/#/R-DDI-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Dictyostelium discoideum 29108 R-DDI-1676109 https://reactome.org/PathwayBrowser/#/R-DDI-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Dictyostelium discoideum 29108 R-DDI-1676206 https://reactome.org/PathwayBrowser/#/R-DDI-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Dictyostelium discoideum 29108 R-DDI-1855153 https://reactome.org/PathwayBrowser/#/R-DDI-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Dictyostelium discoideum 29108 R-DDI-1855177 https://reactome.org/PathwayBrowser/#/R-DDI-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Dictyostelium discoideum 29108 R-DDI-1855214 https://reactome.org/PathwayBrowser/#/R-DDI-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Dictyostelium discoideum 29108 R-DDI-1855221 https://reactome.org/PathwayBrowser/#/R-DDI-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Dictyostelium discoideum 29108 R-DDI-202111 https://reactome.org/PathwayBrowser/#/R-DDI-202111 AKT1 phosphorylates eNOS IEA Dictyostelium discoideum 29108 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 29108 R-DDI-202137 https://reactome.org/PathwayBrowser/#/R-DDI-202137 AKT1 binds eNOS complex via HSP90 IEA Dictyostelium discoideum 29108 R-DDI-2161768 https://reactome.org/PathwayBrowser/#/R-DDI-2161768 EXA4 is converted to EXC4 by LTC4S IEA Dictyostelium discoideum 29108 R-DDI-2161907 https://reactome.org/PathwayBrowser/#/R-DDI-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Dictyostelium discoideum 29108 R-DDI-2161917 https://reactome.org/PathwayBrowser/#/R-DDI-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Dictyostelium discoideum 29108 R-DDI-2586748 https://reactome.org/PathwayBrowser/#/R-DDI-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ IEA Dictyostelium discoideum 29108 R-DDI-265296 https://reactome.org/PathwayBrowser/#/R-DDI-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Dictyostelium discoideum 29108 R-DDI-266050 https://reactome.org/PathwayBrowser/#/R-DDI-266050 LTA4 is converted to LTC4 by LTC4S IEA Dictyostelium discoideum 29108 R-DDI-266051 https://reactome.org/PathwayBrowser/#/R-DDI-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Dictyostelium discoideum 29108 R-DDI-2684901 https://reactome.org/PathwayBrowser/#/R-DDI-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Dictyostelium discoideum 29108 R-DDI-2730867 https://reactome.org/PathwayBrowser/#/R-DDI-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Dictyostelium discoideum 29108 R-DDI-2730872 https://reactome.org/PathwayBrowser/#/R-DDI-2730872 Activation of Calcineurin IEA Dictyostelium discoideum 29108 R-DDI-2744242 https://reactome.org/PathwayBrowser/#/R-DDI-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Dictyostelium discoideum 29108 R-DDI-3295579 https://reactome.org/PathwayBrowser/#/R-DDI-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Dictyostelium discoideum 29108 R-DDI-354173 https://reactome.org/PathwayBrowser/#/R-DDI-354173 Activation of Rap1 by cytosolic GEFs IEA Dictyostelium discoideum 29108 R-DDI-372448 https://reactome.org/PathwayBrowser/#/R-DDI-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Dictyostelium discoideum 29108 R-DDI-418309 https://reactome.org/PathwayBrowser/#/R-DDI-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Dictyostelium discoideum 29108 R-DDI-428262 https://reactome.org/PathwayBrowser/#/R-DDI-428262 ACER3 hydrolyzes phytoceramide IEA Dictyostelium discoideum 29108 R-DDI-4551465 https://reactome.org/PathwayBrowser/#/R-DDI-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Dictyostelium discoideum 29108 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 29108 R-DDI-5218813 https://reactome.org/PathwayBrowser/#/R-DDI-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Dictyostelium discoideum 29108 R-DDI-5218823 https://reactome.org/PathwayBrowser/#/R-DDI-5218823 PKC phosphorylates sphingosine kinase 1 IEA Dictyostelium discoideum 29108 R-DDI-5223304 https://reactome.org/PathwayBrowser/#/R-DDI-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Dictyostelium discoideum 29108 R-DDI-5333678 https://reactome.org/PathwayBrowser/#/R-DDI-5333678 CPNEs bind PL IEA Dictyostelium discoideum 29108 R-DDI-5626507 https://reactome.org/PathwayBrowser/#/R-DDI-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Dictyostelium discoideum 29108 R-DDI-5626549 https://reactome.org/PathwayBrowser/#/R-DDI-5626549 IQGAPs bind CALM1 IEA Dictyostelium discoideum 29108 R-DDI-5694018 https://reactome.org/PathwayBrowser/#/R-DDI-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Dictyostelium discoideum 29108 R-DDI-71181 https://reactome.org/PathwayBrowser/#/R-DDI-71181 FAH cleaves 4FAA IEA Dictyostelium discoideum 29108 R-DDI-71401 https://reactome.org/PathwayBrowser/#/R-DDI-71401 OGDH dimer decarboxylates 2-OG IEA Dictyostelium discoideum 29108 R-DDI-74885 https://reactome.org/PathwayBrowser/#/R-DDI-74885 GUCYs converts GTP to cGMP IEA Dictyostelium discoideum 29108 R-DDI-8949178 https://reactome.org/PathwayBrowser/#/R-DDI-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Dictyostelium discoideum 29108 R-DDI-9619376 https://reactome.org/PathwayBrowser/#/R-DDI-9619376 CAMK1 binds calmodulin IEA Dictyostelium discoideum 29108 R-DDI-9659568 https://reactome.org/PathwayBrowser/#/R-DDI-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Dictyostelium discoideum 29108 R-DDI-9701055 https://reactome.org/PathwayBrowser/#/R-DDI-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Dictyostelium discoideum 29108 R-DDI-9707186 https://reactome.org/PathwayBrowser/#/R-DDI-9707186 ALOX5 binds ALOX5 inhibitors IEA Dictyostelium discoideum 29108 R-DDI-9717215 https://reactome.org/PathwayBrowser/#/R-DDI-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Dictyostelium discoideum 29108 R-DDI-9853499 https://reactome.org/PathwayBrowser/#/R-DDI-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 29108 R-DDI-9853512 https://reactome.org/PathwayBrowser/#/R-DDI-9853512 DLST transfers succinyl to CoA IEA Dictyostelium discoideum 29108 R-DME-111915 https://reactome.org/PathwayBrowser/#/R-DME-111915 CAMK4 autophosphorylates IEA Drosophila melanogaster 29108 R-DME-111930 https://reactome.org/PathwayBrowser/#/R-DME-111930 Adenylate cyclase produces cAMP IEA Drosophila melanogaster 29108 R-DME-111956 https://reactome.org/PathwayBrowser/#/R-DME-111956 Calmodulin activates Cam-PDE 1 IEA Drosophila melanogaster 29108 R-DME-111966 https://reactome.org/PathwayBrowser/#/R-DME-111966 GRK2 binds CALM1:4Ca2+ IEA Drosophila melanogaster 29108 R-DME-111970 https://reactome.org/PathwayBrowser/#/R-DME-111970 PKC phosphorylates GRK2 IEA Drosophila melanogaster 29108 R-DME-114553 https://reactome.org/PathwayBrowser/#/R-DME-114553 Activation of conventional Protein Kinase C IEA Drosophila melanogaster 29108 R-DME-114683 https://reactome.org/PathwayBrowser/#/R-DME-114683 Phosphorylation of Platelet Sec-1 IEA Drosophila melanogaster 29108 R-DME-114684 https://reactome.org/PathwayBrowser/#/R-DME-114684 Phosphorylation of Syntaxin-4 IEA Drosophila melanogaster 29108 R-DME-1168373 https://reactome.org/PathwayBrowser/#/R-DME-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Drosophila melanogaster 29108 R-DME-1168376 https://reactome.org/PathwayBrowser/#/R-DME-1168376 STIM1 oligomerizes IEA Drosophila melanogaster 29108 R-DME-139854 https://reactome.org/PathwayBrowser/#/R-DME-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Drosophila melanogaster 29108 R-DME-139941 https://reactome.org/PathwayBrowser/#/R-DME-139941 Binding of IP3 to IP3 receptor IEA Drosophila melanogaster 29108 R-DME-1482679 https://reactome.org/PathwayBrowser/#/R-DME-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Drosophila melanogaster 29108 R-DME-1482776 https://reactome.org/PathwayBrowser/#/R-DME-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Drosophila melanogaster 29108 R-DME-1482816 https://reactome.org/PathwayBrowser/#/R-DME-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Drosophila melanogaster 29108 R-DME-1482868 https://reactome.org/PathwayBrowser/#/R-DME-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Drosophila melanogaster 29108 R-DME-1482887 https://reactome.org/PathwayBrowser/#/R-DME-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Drosophila melanogaster 29108 R-DME-1482907 https://reactome.org/PathwayBrowser/#/R-DME-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Drosophila melanogaster 29108 R-DME-1497784 https://reactome.org/PathwayBrowser/#/R-DME-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Drosophila melanogaster 29108 R-DME-1497796 https://reactome.org/PathwayBrowser/#/R-DME-1497796 BH2 binding can lead to eNOS uncoupling IEA Drosophila melanogaster 29108 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 29108 R-DME-1602368 https://reactome.org/PathwayBrowser/#/R-DME-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Drosophila melanogaster 29108 R-DME-1602374 https://reactome.org/PathwayBrowser/#/R-DME-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Drosophila melanogaster 29108 R-DME-1602377 https://reactome.org/PathwayBrowser/#/R-DME-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Drosophila melanogaster 29108 R-DME-1602398 https://reactome.org/PathwayBrowser/#/R-DME-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Drosophila melanogaster 29108 R-DME-1602417 https://reactome.org/PathwayBrowser/#/R-DME-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Drosophila melanogaster 29108 R-DME-1602446 https://reactome.org/PathwayBrowser/#/R-DME-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Drosophila melanogaster 29108 R-DME-1675928 https://reactome.org/PathwayBrowser/#/R-DME-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Drosophila melanogaster 29108 R-DME-1675939 https://reactome.org/PathwayBrowser/#/R-DME-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Drosophila melanogaster 29108 R-DME-1675961 https://reactome.org/PathwayBrowser/#/R-DME-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Drosophila melanogaster 29108 R-DME-1676024 https://reactome.org/PathwayBrowser/#/R-DME-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Drosophila melanogaster 29108 R-DME-1676109 https://reactome.org/PathwayBrowser/#/R-DME-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Drosophila melanogaster 29108 R-DME-1676206 https://reactome.org/PathwayBrowser/#/R-DME-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Drosophila melanogaster 29108 R-DME-1678650 https://reactome.org/PathwayBrowser/#/R-DME-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Drosophila melanogaster 29108 R-DME-1793182 https://reactome.org/PathwayBrowser/#/R-DME-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Drosophila melanogaster 29108 R-DME-1855153 https://reactome.org/PathwayBrowser/#/R-DME-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Drosophila melanogaster 29108 R-DME-1855177 https://reactome.org/PathwayBrowser/#/R-DME-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Drosophila melanogaster 29108 R-DME-1855214 https://reactome.org/PathwayBrowser/#/R-DME-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Drosophila melanogaster 29108 R-DME-1855221 https://reactome.org/PathwayBrowser/#/R-DME-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Drosophila melanogaster 29108 R-DME-202111 https://reactome.org/PathwayBrowser/#/R-DME-202111 AKT1 phosphorylates eNOS IEA Drosophila melanogaster 29108 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 29108 R-DME-202137 https://reactome.org/PathwayBrowser/#/R-DME-202137 AKT1 binds eNOS complex via HSP90 IEA Drosophila melanogaster 29108 R-DME-2025890 https://reactome.org/PathwayBrowser/#/R-DME-2025890 Calcineurin binds NFATC1,2,3 IEA Drosophila melanogaster 29108 R-DME-2089943 https://reactome.org/PathwayBrowser/#/R-DME-2089943 TRPC1 translocates calcium from the extracellular region to the cytosol IEA Drosophila melanogaster 29108 R-DME-210420 https://reactome.org/PathwayBrowser/#/R-DME-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Drosophila melanogaster 29108 R-DME-210430 https://reactome.org/PathwayBrowser/#/R-DME-210430 Release of L-Glutamate at the synapse IEA Drosophila melanogaster 29108 R-DME-2514867 https://reactome.org/PathwayBrowser/#/R-DME-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Drosophila melanogaster 29108 R-DME-265645 https://reactome.org/PathwayBrowser/#/R-DME-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Drosophila melanogaster 29108 R-DME-2684901 https://reactome.org/PathwayBrowser/#/R-DME-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Drosophila melanogaster 29108 R-DME-2730664 https://reactome.org/PathwayBrowser/#/R-DME-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Drosophila melanogaster 29108 R-DME-2730849 https://reactome.org/PathwayBrowser/#/R-DME-2730849 Calcineurin binds and dephosphorylates NFAT IEA Drosophila melanogaster 29108 R-DME-2730867 https://reactome.org/PathwayBrowser/#/R-DME-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Drosophila melanogaster 29108 R-DME-2730872 https://reactome.org/PathwayBrowser/#/R-DME-2730872 Activation of Calcineurin IEA Drosophila melanogaster 29108 R-DME-2744242 https://reactome.org/PathwayBrowser/#/R-DME-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Drosophila melanogaster 29108 R-DME-2744361 https://reactome.org/PathwayBrowser/#/R-DME-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Drosophila melanogaster 29108 R-DME-3229181 https://reactome.org/PathwayBrowser/#/R-DME-3229181 CALM1:Ca2+ binds CNG channel IEA Drosophila melanogaster 29108 R-DME-3295579 https://reactome.org/PathwayBrowser/#/R-DME-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Drosophila melanogaster 29108 R-DME-354149 https://reactome.org/PathwayBrowser/#/R-DME-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Drosophila melanogaster 29108 R-DME-372448 https://reactome.org/PathwayBrowser/#/R-DME-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Drosophila melanogaster 29108 R-DME-377640 https://reactome.org/PathwayBrowser/#/R-DME-377640 Autophosphorylation of SRC IEA Drosophila melanogaster 29108 R-DME-377641 https://reactome.org/PathwayBrowser/#/R-DME-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Drosophila melanogaster 29108 R-DME-377643 https://reactome.org/PathwayBrowser/#/R-DME-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Drosophila melanogaster 29108 R-DME-377644 https://reactome.org/PathwayBrowser/#/R-DME-377644 Release of CSK from SRC IEA Drosophila melanogaster 29108 R-DME-3827958 https://reactome.org/PathwayBrowser/#/R-DME-3827958 E-cadherin degradation by MMP9, KLK7 IEA Drosophila melanogaster 29108 R-DME-399712 https://reactome.org/PathwayBrowser/#/R-DME-399712 Activation of Ca permeable AMPA receptors IEA Drosophila melanogaster 29108 R-DME-416639 https://reactome.org/PathwayBrowser/#/R-DME-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Drosophila melanogaster 29108 R-DME-418309 https://reactome.org/PathwayBrowser/#/R-DME-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Drosophila melanogaster 29108 R-DME-418365 https://reactome.org/PathwayBrowser/#/R-DME-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Drosophila melanogaster 29108 R-DME-419001 https://reactome.org/PathwayBrowser/#/R-DME-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Drosophila melanogaster 29108 R-DME-421007 https://reactome.org/PathwayBrowser/#/R-DME-421007 Endocytosis of Ca impermeable AMPA receptors IEA Drosophila melanogaster 29108 R-DME-4224014 https://reactome.org/PathwayBrowser/#/R-DME-4224014 E-cadherin degradation by ADAM10, ADAM15 IEA Drosophila melanogaster 29108 R-DME-425661 https://reactome.org/PathwayBrowser/#/R-DME-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Drosophila melanogaster 29108 R-DME-425678 https://reactome.org/PathwayBrowser/#/R-DME-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Drosophila melanogaster 29108 R-DME-425822 https://reactome.org/PathwayBrowser/#/R-DME-425822 K+-independent Li+/Ca2+ exchanger transport IEA Drosophila melanogaster 29108 R-DME-427910 https://reactome.org/PathwayBrowser/#/R-DME-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Drosophila melanogaster 29108 R-DME-429415 https://reactome.org/PathwayBrowser/#/R-DME-429415 SYK binds to integrin alphaIIb beta3 IEA Drosophila melanogaster 29108 R-DME-429441 https://reactome.org/PathwayBrowser/#/R-DME-429441 SYK activation by SRC IEA Drosophila melanogaster 29108 R-DME-432164 https://reactome.org/PathwayBrowser/#/R-DME-432164 Ca2+ influx into the post-synaptic cell IEA Drosophila melanogaster 29108 R-DME-4332358 https://reactome.org/PathwayBrowser/#/R-DME-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Drosophila melanogaster 29108 R-DME-4332359 https://reactome.org/PathwayBrowser/#/R-DME-4332359 Active calmodulin binds CAMK2 IEA Drosophila melanogaster 29108 R-DME-4332363 https://reactome.org/PathwayBrowser/#/R-DME-4332363 Autophosphorylation and activation of CAMK2 IEA Drosophila melanogaster 29108 R-DME-434802 https://reactome.org/PathwayBrowser/#/R-DME-434802 Calcium influx via CRAC TAS Drosophila melanogaster 29108 R-DME-438037 https://reactome.org/PathwayBrowser/#/R-DME-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Drosophila melanogaster 29108 R-DME-445699 https://reactome.org/PathwayBrowser/#/R-DME-445699 ATP Hydrolysis By Myosin IEA Drosophila melanogaster 29108 R-DME-445700 https://reactome.org/PathwayBrowser/#/R-DME-445700 Myosin Binds ATP IEA Drosophila melanogaster 29108 R-DME-445704 https://reactome.org/PathwayBrowser/#/R-DME-445704 Calcium Binds Caldesmon IEA Drosophila melanogaster 29108 R-DME-445705 https://reactome.org/PathwayBrowser/#/R-DME-445705 Release Of ADP From Myosin IEA Drosophila melanogaster 29108 R-DME-451311 https://reactome.org/PathwayBrowser/#/R-DME-451311 Activation of Ca-permeable Kainate receptors IEA Drosophila melanogaster 29108 R-DME-4551451 https://reactome.org/PathwayBrowser/#/R-DME-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Drosophila melanogaster 29108 R-DME-4551465 https://reactome.org/PathwayBrowser/#/R-DME-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Drosophila melanogaster 29108 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 29108 R-DME-5218813 https://reactome.org/PathwayBrowser/#/R-DME-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Drosophila melanogaster 29108 R-DME-5218823 https://reactome.org/PathwayBrowser/#/R-DME-5218823 PKC phosphorylates sphingosine kinase 1 IEA Drosophila melanogaster 29108 R-DME-5223304 https://reactome.org/PathwayBrowser/#/R-DME-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Drosophila melanogaster 29108 R-DME-5577213 https://reactome.org/PathwayBrowser/#/R-DME-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Drosophila melanogaster 29108 R-DME-5626316 https://reactome.org/PathwayBrowser/#/R-DME-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Drosophila melanogaster 29108 R-DME-5672969 https://reactome.org/PathwayBrowser/#/R-DME-5672969 Phosphorylation of RAF IEA Drosophila melanogaster 29108 R-DME-5672972 https://reactome.org/PathwayBrowser/#/R-DME-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Drosophila melanogaster 29108 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 29108 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 29108 R-DME-5672980 https://reactome.org/PathwayBrowser/#/R-DME-5672980 Dissociation of RAS:RAF complex IEA Drosophila melanogaster 29108 R-DME-5694018 https://reactome.org/PathwayBrowser/#/R-DME-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Drosophila melanogaster 29108 R-DME-622326 https://reactome.org/PathwayBrowser/#/R-DME-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Drosophila melanogaster 29108 R-DME-629595 https://reactome.org/PathwayBrowser/#/R-DME-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 29108 R-DME-71181 https://reactome.org/PathwayBrowser/#/R-DME-71181 FAH cleaves 4FAA IEA Drosophila melanogaster 29108 R-DME-71401 https://reactome.org/PathwayBrowser/#/R-DME-71401 OGDH dimer decarboxylates 2-OG IEA Drosophila melanogaster 29108 R-DME-71541 https://reactome.org/PathwayBrowser/#/R-DME-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Drosophila melanogaster 29108 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 29108 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 29108 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 29108 R-DME-8857662 https://reactome.org/PathwayBrowser/#/R-DME-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Drosophila melanogaster 29108 R-DME-8862771 https://reactome.org/PathwayBrowser/#/R-DME-8862771 PLA2G2A binds bacterial phospholipids IEA Drosophila melanogaster 29108 R-DME-8878787 https://reactome.org/PathwayBrowser/#/R-DME-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Drosophila melanogaster 29108 R-DME-888589 https://reactome.org/PathwayBrowser/#/R-DME-888589 Release of GABA at the synapse IEA Drosophila melanogaster 29108 R-DME-8934446 https://reactome.org/PathwayBrowser/#/R-DME-8934446 Activated PKC phosphorylates SHC1 IEA Drosophila melanogaster 29108 R-DME-8949178 https://reactome.org/PathwayBrowser/#/R-DME-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Drosophila melanogaster 29108 R-DME-8949688 https://reactome.org/PathwayBrowser/#/R-DME-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Drosophila melanogaster 29108 R-DME-936883 https://reactome.org/PathwayBrowser/#/R-DME-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Drosophila melanogaster 29108 R-DME-9619376 https://reactome.org/PathwayBrowser/#/R-DME-9619376 CAMK1 binds calmodulin IEA Drosophila melanogaster 29108 R-DME-9653585 https://reactome.org/PathwayBrowser/#/R-DME-9653585 S-Farn-Me KRAS4B binds calmodulin IEA Drosophila melanogaster 29108 R-DME-9654521 https://reactome.org/PathwayBrowser/#/R-DME-9654521 Calmodulin dissociates KRAS4B from the plasma membrane IEA Drosophila melanogaster 29108 R-DME-9654523 https://reactome.org/PathwayBrowser/#/R-DME-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Drosophila melanogaster 29108 R-DME-9654525 https://reactome.org/PathwayBrowser/#/R-DME-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ IEA Drosophila melanogaster 29108 R-DME-9654533 https://reactome.org/PathwayBrowser/#/R-DME-9654533 KRAS4B recycles to the plasma membrane IEA Drosophila melanogaster 29108 R-DME-9657599 https://reactome.org/PathwayBrowser/#/R-DME-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Drosophila melanogaster 29108 R-DME-9657603 https://reactome.org/PathwayBrowser/#/R-DME-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Drosophila melanogaster 29108 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 29108 R-DME-9657608 https://reactome.org/PathwayBrowser/#/R-DME-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Drosophila melanogaster 29108 R-DME-9701055 https://reactome.org/PathwayBrowser/#/R-DME-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Drosophila melanogaster 29108 R-DME-9701141 https://reactome.org/PathwayBrowser/#/R-DME-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Drosophila melanogaster 29108 R-DME-9717215 https://reactome.org/PathwayBrowser/#/R-DME-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Drosophila melanogaster 29108 R-DME-9853499 https://reactome.org/PathwayBrowser/#/R-DME-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 29108 R-DME-9853512 https://reactome.org/PathwayBrowser/#/R-DME-9853512 DLST transfers succinyl to CoA IEA Drosophila melanogaster 29108 R-DRE-111881 https://reactome.org/PathwayBrowser/#/R-DRE-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Danio rerio 29108 R-DRE-111883 https://reactome.org/PathwayBrowser/#/R-DRE-111883 Hydrolysis of phosphatidylcholine IEA Danio rerio 29108 R-DRE-114553 https://reactome.org/PathwayBrowser/#/R-DRE-114553 Activation of conventional Protein Kinase C IEA Danio rerio 29108 R-DRE-114684 https://reactome.org/PathwayBrowser/#/R-DRE-114684 Phosphorylation of Syntaxin-4 IEA Danio rerio 29108 R-DRE-1168373 https://reactome.org/PathwayBrowser/#/R-DRE-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Danio rerio 29108 R-DRE-139855 https://reactome.org/PathwayBrowser/#/R-DRE-139855 P2X1-mediated entry of Ca++ from plasma IEA Danio rerio 29108 R-DRE-140686 https://reactome.org/PathwayBrowser/#/R-DRE-140686 factor Va + factor Xa -> Va:Xa complex (prothrombinase) IEA Danio rerio 29108 R-DRE-140736 https://reactome.org/PathwayBrowser/#/R-DRE-140736 factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) IEA Danio rerio 29108 R-DRE-140748 https://reactome.org/PathwayBrowser/#/R-DRE-140748 tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex IEA Danio rerio 29108 R-DRE-140769 https://reactome.org/PathwayBrowser/#/R-DRE-140769 factor VII -> factor VIIa IEA Danio rerio 29108 R-DRE-140777 https://reactome.org/PathwayBrowser/#/R-DRE-140777 factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) IEA Danio rerio 29108 R-DRE-140783 https://reactome.org/PathwayBrowser/#/R-DRE-140783 tissue factor (TF) + factor VII (F7) -> TF:F7 complex IEA Danio rerio 29108 R-DRE-140823 https://reactome.org/PathwayBrowser/#/R-DRE-140823 factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) IEA Danio rerio 29108 R-DRE-140847 https://reactome.org/PathwayBrowser/#/R-DRE-140847 factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain IEA Danio rerio 29108 R-DRE-141026 https://reactome.org/PathwayBrowser/#/R-DRE-141026 Activated protein C cleaves factor Va to factor Vi intermediate form IEA Danio rerio 29108 R-DRE-1482604 https://reactome.org/PathwayBrowser/#/R-DRE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Danio rerio 29108 R-DRE-1482612 https://reactome.org/PathwayBrowser/#/R-DRE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 29108 R-DRE-1482656 https://reactome.org/PathwayBrowser/#/R-DRE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Danio rerio 29108 R-DRE-1482685 https://reactome.org/PathwayBrowser/#/R-DRE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 29108 R-DRE-1482759 https://reactome.org/PathwayBrowser/#/R-DRE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Danio rerio 29108 R-DRE-1482771 https://reactome.org/PathwayBrowser/#/R-DRE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Danio rerio 29108 R-DRE-1482825 https://reactome.org/PathwayBrowser/#/R-DRE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Danio rerio 29108 R-DRE-1482828 https://reactome.org/PathwayBrowser/#/R-DRE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Danio rerio 29108 R-DRE-1482856 https://reactome.org/PathwayBrowser/#/R-DRE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Danio rerio 29108 R-DRE-1482862 https://reactome.org/PathwayBrowser/#/R-DRE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Danio rerio 29108 R-DRE-1482884 https://reactome.org/PathwayBrowser/#/R-DRE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Danio rerio 29108 R-DRE-1482897 https://reactome.org/PathwayBrowser/#/R-DRE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Danio rerio 29108 R-DRE-1482900 https://reactome.org/PathwayBrowser/#/R-DRE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Danio rerio 29108 R-DRE-1602368 https://reactome.org/PathwayBrowser/#/R-DRE-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Danio rerio 29108 R-DRE-1602374 https://reactome.org/PathwayBrowser/#/R-DRE-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Danio rerio 29108 R-DRE-1602377 https://reactome.org/PathwayBrowser/#/R-DRE-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Danio rerio 29108 R-DRE-1602398 https://reactome.org/PathwayBrowser/#/R-DRE-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Danio rerio 29108 R-DRE-1602417 https://reactome.org/PathwayBrowser/#/R-DRE-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Danio rerio 29108 R-DRE-1602446 https://reactome.org/PathwayBrowser/#/R-DRE-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Danio rerio 29108 R-DRE-1676109 https://reactome.org/PathwayBrowser/#/R-DRE-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Danio rerio 29108 R-DRE-1678650 https://reactome.org/PathwayBrowser/#/R-DRE-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Danio rerio 29108 R-DRE-1793182 https://reactome.org/PathwayBrowser/#/R-DRE-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Danio rerio 29108 R-DRE-1855221 https://reactome.org/PathwayBrowser/#/R-DRE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Danio rerio 29108 R-DRE-187020 https://reactome.org/PathwayBrowser/#/R-DRE-187020 Part of pro-beta-NGF is processed to mature beta-NGF IEA Danio rerio 29108 R-DRE-2424243 https://reactome.org/PathwayBrowser/#/R-DRE-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Danio rerio 29108 R-DRE-2581474 https://reactome.org/PathwayBrowser/#/R-DRE-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Danio rerio 29108 R-DRE-2586748 https://reactome.org/PathwayBrowser/#/R-DRE-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ IEA Danio rerio 29108 R-DRE-264976 https://reactome.org/PathwayBrowser/#/R-DRE-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Danio rerio 29108 R-DRE-265153 https://reactome.org/PathwayBrowser/#/R-DRE-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Danio rerio 29108 R-DRE-265301 https://reactome.org/PathwayBrowser/#/R-DRE-265301 Corticotropin cleavage from POMC IEA Danio rerio 29108 R-DRE-2684901 https://reactome.org/PathwayBrowser/#/R-DRE-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Danio rerio 29108 R-DRE-2685505 https://reactome.org/PathwayBrowser/#/R-DRE-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Danio rerio 29108 R-DRE-2744242 https://reactome.org/PathwayBrowser/#/R-DRE-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Danio rerio 29108 R-DRE-3295579 https://reactome.org/PathwayBrowser/#/R-DRE-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Danio rerio 29108 R-DRE-354149 https://reactome.org/PathwayBrowser/#/R-DRE-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Danio rerio 29108 R-DRE-372448 https://reactome.org/PathwayBrowser/#/R-DRE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Danio rerio 29108 R-DRE-377640 https://reactome.org/PathwayBrowser/#/R-DRE-377640 Autophosphorylation of SRC IEA Danio rerio 29108 R-DRE-377641 https://reactome.org/PathwayBrowser/#/R-DRE-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Danio rerio 29108 R-DRE-377644 https://reactome.org/PathwayBrowser/#/R-DRE-377644 Release of CSK from SRC IEA Danio rerio 29108 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 29108 R-DRE-3827958 https://reactome.org/PathwayBrowser/#/R-DRE-3827958 E-cadherin degradation by MMP9, KLK7 IEA Danio rerio 29108 R-DRE-399712 https://reactome.org/PathwayBrowser/#/R-DRE-399712 Activation of Ca permeable AMPA receptors IEA Danio rerio 29108 R-DRE-418309 https://reactome.org/PathwayBrowser/#/R-DRE-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Danio rerio 29108 R-DRE-418365 https://reactome.org/PathwayBrowser/#/R-DRE-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Danio rerio 29108 R-DRE-419001 https://reactome.org/PathwayBrowser/#/R-DRE-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Danio rerio 29108 R-DRE-420739 https://reactome.org/PathwayBrowser/#/R-DRE-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Danio rerio 29108 R-DRE-422021 https://reactome.org/PathwayBrowser/#/R-DRE-422021 PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin IEA Danio rerio 29108 R-DRE-425661 https://reactome.org/PathwayBrowser/#/R-DRE-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Danio rerio 29108 R-DRE-426223 https://reactome.org/PathwayBrowser/#/R-DRE-426223 Cation influx mediated by TRPC3/6/7 IEA Danio rerio 29108 R-DRE-427910 https://reactome.org/PathwayBrowser/#/R-DRE-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Danio rerio 29108 R-DRE-429016 https://reactome.org/PathwayBrowser/#/R-DRE-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Danio rerio 29108 R-DRE-432164 https://reactome.org/PathwayBrowser/#/R-DRE-432164 Ca2+ influx into the post-synaptic cell IEA Danio rerio 29108 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 29108 R-DRE-5218813 https://reactome.org/PathwayBrowser/#/R-DRE-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Danio rerio 29108 R-DRE-5223304 https://reactome.org/PathwayBrowser/#/R-DRE-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Danio rerio 29108 R-DRE-5333678 https://reactome.org/PathwayBrowser/#/R-DRE-5333678 CPNEs bind PL IEA Danio rerio 29108 R-DRE-5591040 https://reactome.org/PathwayBrowser/#/R-DRE-5591040 Activated protein C cleaves Factor Va intermediate form for Factor Va IEA Danio rerio 29108 R-DRE-5591086 https://reactome.org/PathwayBrowser/#/R-DRE-5591086 SERPINA5 binds activated protein C IEA Danio rerio 29108 R-DRE-5604929 https://reactome.org/PathwayBrowser/#/R-DRE-5604929 Activated protein C binds Protein S IEA Danio rerio 29108 R-DRE-5621615 https://reactome.org/PathwayBrowser/#/R-DRE-5621615 CD209 binds ICAM3 IEA Danio rerio 29108 R-DRE-5668629 https://reactome.org/PathwayBrowser/#/R-DRE-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Danio rerio 29108 R-DRE-5672304 https://reactome.org/PathwayBrowser/#/R-DRE-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 IEA Danio rerio 29108 R-DRE-5694018 https://reactome.org/PathwayBrowser/#/R-DRE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Danio rerio 29108 R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 29108 R-DRE-622326 https://reactome.org/PathwayBrowser/#/R-DRE-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Danio rerio 29108 R-DRE-629595 https://reactome.org/PathwayBrowser/#/R-DRE-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Danio rerio 29108 R-DRE-6798474 https://reactome.org/PathwayBrowser/#/R-DRE-6798474 S100A8:S100A9 binds Zn2+ IEA Danio rerio 29108 R-DRE-6798489 https://reactome.org/PathwayBrowser/#/R-DRE-6798489 S100A7 or S100A7A binds Zn2+ IEA Danio rerio 29108 R-DRE-6798528 https://reactome.org/PathwayBrowser/#/R-DRE-6798528 S100A8:S100A9 binds Mn2+ IEA Danio rerio 29108 R-DRE-6804527 https://reactome.org/PathwayBrowser/#/R-DRE-6804527 INTL1 binds bacterial glycans IEA Danio rerio 29108 R-DRE-71401 https://reactome.org/PathwayBrowser/#/R-DRE-71401 OGDH dimer decarboxylates 2-OG IEA Danio rerio 29108 R-DRE-8848658 https://reactome.org/PathwayBrowser/#/R-DRE-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Danio rerio 29108 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 29108 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 29108 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 29108 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 29108 R-DRE-8878787 https://reactome.org/PathwayBrowser/#/R-DRE-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Danio rerio 29108 R-DRE-8932633 https://reactome.org/PathwayBrowser/#/R-DRE-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Danio rerio 29108 R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 29108 R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 29108 R-DRE-9626848 https://reactome.org/PathwayBrowser/#/R-DRE-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Danio rerio 29108 R-DRE-9701055 https://reactome.org/PathwayBrowser/#/R-DRE-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Danio rerio 29108 R-DRE-9701141 https://reactome.org/PathwayBrowser/#/R-DRE-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Danio rerio 29108 R-DRE-9756177 https://reactome.org/PathwayBrowser/#/R-DRE-9756177 PON1,3 hydrolyse ATVL to ATV IEA Danio rerio 29108 R-DRE-9853499 https://reactome.org/PathwayBrowser/#/R-DRE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Danio rerio 29108 R-DRE-9853512 https://reactome.org/PathwayBrowser/#/R-DRE-9853512 DLST transfers succinyl to CoA IEA Danio rerio 29108 R-GGA-111881 https://reactome.org/PathwayBrowser/#/R-GGA-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Gallus gallus 29108 R-GGA-111883 https://reactome.org/PathwayBrowser/#/R-GGA-111883 Hydrolysis of phosphatidylcholine IEA Gallus gallus 29108 R-GGA-111915 https://reactome.org/PathwayBrowser/#/R-GGA-111915 CAMK4 autophosphorylates IEA Gallus gallus 29108 R-GGA-111930 https://reactome.org/PathwayBrowser/#/R-GGA-111930 Adenylate cyclase produces cAMP IEA Gallus gallus 29108 R-GGA-111956 https://reactome.org/PathwayBrowser/#/R-GGA-111956 Calmodulin activates Cam-PDE 1 IEA Gallus gallus 29108 R-GGA-111966 https://reactome.org/PathwayBrowser/#/R-GGA-111966 GRK2 binds CALM1:4Ca2+ IEA Gallus gallus 29108 R-GGA-111970 https://reactome.org/PathwayBrowser/#/R-GGA-111970 PKC phosphorylates GRK2 IEA Gallus gallus 29108 R-GGA-114553 https://reactome.org/PathwayBrowser/#/R-GGA-114553 Activation of conventional Protein Kinase C IEA Gallus gallus 29108 R-GGA-114683 https://reactome.org/PathwayBrowser/#/R-GGA-114683 Phosphorylation of Platelet Sec-1 IEA Gallus gallus 29108 R-GGA-114697 https://reactome.org/PathwayBrowser/#/R-GGA-114697 Activated thrombin (factor IIa) cleaves PAR3,4, activating them IEA Gallus gallus 29108 R-GGA-1168373 https://reactome.org/PathwayBrowser/#/R-GGA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Gallus gallus 29108 R-GGA-1168376 https://reactome.org/PathwayBrowser/#/R-GGA-1168376 STIM1 oligomerizes IEA Gallus gallus 29108 R-GGA-1168635 https://reactome.org/PathwayBrowser/#/R-GGA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Gallus gallus 29108 R-GGA-1183128 https://reactome.org/PathwayBrowser/#/R-GGA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Gallus gallus 29108 R-GGA-139854 https://reactome.org/PathwayBrowser/#/R-GGA-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Gallus gallus 29108 R-GGA-139855 https://reactome.org/PathwayBrowser/#/R-GGA-139855 P2X1-mediated entry of Ca++ from plasma IEA Gallus gallus 29108 R-GGA-139941 https://reactome.org/PathwayBrowser/#/R-GGA-139941 Binding of IP3 to IP3 receptor IEA Gallus gallus 29108 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 29108 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 29108 R-GGA-140686 https://reactome.org/PathwayBrowser/#/R-GGA-140686 factor Va + factor Xa -> Va:Xa complex (prothrombinase) IEA Gallus gallus 29108 R-GGA-140696 https://reactome.org/PathwayBrowser/#/R-GGA-140696 factor V -> factor Va + factor V activation peptide IEA Gallus gallus 29108 R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 29108 R-GGA-140736 https://reactome.org/PathwayBrowser/#/R-GGA-140736 factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) IEA Gallus gallus 29108 R-GGA-140748 https://reactome.org/PathwayBrowser/#/R-GGA-140748 tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex IEA Gallus gallus 29108 R-GGA-140769 https://reactome.org/PathwayBrowser/#/R-GGA-140769 factor VII -> factor VIIa IEA Gallus gallus 29108 R-GGA-140777 https://reactome.org/PathwayBrowser/#/R-GGA-140777 factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) IEA Gallus gallus 29108 R-GGA-140783 https://reactome.org/PathwayBrowser/#/R-GGA-140783 tissue factor (TF) + factor VII (F7) -> TF:F7 complex IEA Gallus gallus 29108 R-GGA-140791 https://reactome.org/PathwayBrowser/#/R-GGA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Gallus gallus 29108 R-GGA-140823 https://reactome.org/PathwayBrowser/#/R-GGA-140823 factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) IEA Gallus gallus 29108 R-GGA-140825 https://reactome.org/PathwayBrowser/#/R-GGA-140825 TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa IEA Gallus gallus 29108 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 29108 R-GGA-140847 https://reactome.org/PathwayBrowser/#/R-GGA-140847 factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain IEA Gallus gallus 29108 R-GGA-140851 https://reactome.org/PathwayBrowser/#/R-GGA-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Gallus gallus 29108 R-GGA-140870 https://reactome.org/PathwayBrowser/#/R-GGA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Gallus gallus 29108 R-GGA-140872 https://reactome.org/PathwayBrowser/#/R-GGA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Gallus gallus 29108 R-GGA-141026 https://reactome.org/PathwayBrowser/#/R-GGA-141026 Activated protein C cleaves factor Va to factor Vi intermediate form IEA Gallus gallus 29108 R-GGA-1482604 https://reactome.org/PathwayBrowser/#/R-GGA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Gallus gallus 29108 R-GGA-1482612 https://reactome.org/PathwayBrowser/#/R-GGA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 29108 R-GGA-1482656 https://reactome.org/PathwayBrowser/#/R-GGA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Gallus gallus 29108 R-GGA-1482679 https://reactome.org/PathwayBrowser/#/R-GGA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Gallus gallus 29108 R-GGA-1482685 https://reactome.org/PathwayBrowser/#/R-GGA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 29108 R-GGA-1482759 https://reactome.org/PathwayBrowser/#/R-GGA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Gallus gallus 29108 R-GGA-1482771 https://reactome.org/PathwayBrowser/#/R-GGA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Gallus gallus 29108 R-GGA-1482776 https://reactome.org/PathwayBrowser/#/R-GGA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Gallus gallus 29108 R-GGA-1482816 https://reactome.org/PathwayBrowser/#/R-GGA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Gallus gallus 29108 R-GGA-1482825 https://reactome.org/PathwayBrowser/#/R-GGA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Gallus gallus 29108 R-GGA-1482828 https://reactome.org/PathwayBrowser/#/R-GGA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Gallus gallus 29108 R-GGA-1482856 https://reactome.org/PathwayBrowser/#/R-GGA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Gallus gallus 29108 R-GGA-1482862 https://reactome.org/PathwayBrowser/#/R-GGA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Gallus gallus 29108 R-GGA-1482868 https://reactome.org/PathwayBrowser/#/R-GGA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Gallus gallus 29108 R-GGA-1482884 https://reactome.org/PathwayBrowser/#/R-GGA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Gallus gallus 29108 R-GGA-1482887 https://reactome.org/PathwayBrowser/#/R-GGA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Gallus gallus 29108 R-GGA-1482897 https://reactome.org/PathwayBrowser/#/R-GGA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Gallus gallus 29108 R-GGA-1482900 https://reactome.org/PathwayBrowser/#/R-GGA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Gallus gallus 29108 R-GGA-1482907 https://reactome.org/PathwayBrowser/#/R-GGA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Gallus gallus 29108 R-GGA-1497784 https://reactome.org/PathwayBrowser/#/R-GGA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Gallus gallus 29108 R-GGA-1497796 https://reactome.org/PathwayBrowser/#/R-GGA-1497796 BH2 binding can lead to eNOS uncoupling IEA Gallus gallus 29108 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 29108 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 29108 R-GGA-158164 https://reactome.org/PathwayBrowser/#/R-GGA-158164 factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) IEA Gallus gallus 29108 R-GGA-158278 https://reactome.org/PathwayBrowser/#/R-GGA-158278 factor VIIIa + factor IXa -> factor VIIIa:factor IXa IEA Gallus gallus 29108 R-GGA-158333 https://reactome.org/PathwayBrowser/#/R-GGA-158333 factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) IEA Gallus gallus 29108 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 29108 R-GGA-1602368 https://reactome.org/PathwayBrowser/#/R-GGA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Gallus gallus 29108 R-GGA-1602374 https://reactome.org/PathwayBrowser/#/R-GGA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Gallus gallus 29108 R-GGA-1602377 https://reactome.org/PathwayBrowser/#/R-GGA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Gallus gallus 29108 R-GGA-1602398 https://reactome.org/PathwayBrowser/#/R-GGA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Gallus gallus 29108 R-GGA-1602417 https://reactome.org/PathwayBrowser/#/R-GGA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Gallus gallus 29108 R-GGA-1602446 https://reactome.org/PathwayBrowser/#/R-GGA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Gallus gallus 29108 R-GGA-1606789 https://reactome.org/PathwayBrowser/#/R-GGA-1606789 ARSB hydrolyses DS IEA Gallus gallus 29108 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 29108 R-GGA-1606839 https://reactome.org/PathwayBrowser/#/R-GGA-1606839 ARSC hydrolyzes steroid sulfates IEA Gallus gallus 29108 R-GGA-1614362 https://reactome.org/PathwayBrowser/#/R-GGA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Gallus gallus 29108 R-GGA-166721 https://reactome.org/PathwayBrowser/#/R-GGA-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa IEA Gallus gallus 29108 R-GGA-166726 https://reactome.org/PathwayBrowser/#/R-GGA-166726 Activation of MASPs IEA Gallus gallus 29108 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus 29108 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus 29108 R-GGA-1675928 https://reactome.org/PathwayBrowser/#/R-GGA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Gallus gallus 29108 R-GGA-1675939 https://reactome.org/PathwayBrowser/#/R-GGA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Gallus gallus 29108 R-GGA-1675961 https://reactome.org/PathwayBrowser/#/R-GGA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Gallus gallus 29108 R-GGA-1676024 https://reactome.org/PathwayBrowser/#/R-GGA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Gallus gallus 29108 R-GGA-1676109 https://reactome.org/PathwayBrowser/#/R-GGA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Gallus gallus 29108 R-GGA-1676206 https://reactome.org/PathwayBrowser/#/R-GGA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Gallus gallus 29108 R-GGA-1678650 https://reactome.org/PathwayBrowser/#/R-GGA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Gallus gallus 29108 R-GGA-173626 https://reactome.org/PathwayBrowser/#/R-GGA-173626 Activation of C1r IEA Gallus gallus 29108 R-GGA-1793182 https://reactome.org/PathwayBrowser/#/R-GGA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Gallus gallus 29108 R-GGA-1793207 https://reactome.org/PathwayBrowser/#/R-GGA-1793207 ARSB hydrolyses C4S/C6S chains IEA Gallus gallus 29108 R-GGA-1855153 https://reactome.org/PathwayBrowser/#/R-GGA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Gallus gallus 29108 R-GGA-1855177 https://reactome.org/PathwayBrowser/#/R-GGA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Gallus gallus 29108 R-GGA-1855214 https://reactome.org/PathwayBrowser/#/R-GGA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Gallus gallus 29108 R-GGA-1855221 https://reactome.org/PathwayBrowser/#/R-GGA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Gallus gallus 29108 R-GGA-187020 https://reactome.org/PathwayBrowser/#/R-GGA-187020 Part of pro-beta-NGF is processed to mature beta-NGF IEA Gallus gallus 29108 R-GGA-202110 https://reactome.org/PathwayBrowser/#/R-GGA-202110 eNOS:Caveolin-1 complex binds to CaM IEA Gallus gallus 29108 R-GGA-202111 https://reactome.org/PathwayBrowser/#/R-GGA-202111 AKT1 phosphorylates eNOS IEA Gallus gallus 29108 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 29108 R-GGA-202129 https://reactome.org/PathwayBrowser/#/R-GGA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Gallus gallus 29108 R-GGA-202137 https://reactome.org/PathwayBrowser/#/R-GGA-202137 AKT1 binds eNOS complex via HSP90 IEA Gallus gallus 29108 R-GGA-202144 https://reactome.org/PathwayBrowser/#/R-GGA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Gallus gallus 29108 R-GGA-2025890 https://reactome.org/PathwayBrowser/#/R-GGA-2025890 Calcineurin binds NFATC1,2,3 IEA Gallus gallus 29108 R-GGA-2089943 https://reactome.org/PathwayBrowser/#/R-GGA-2089943 TRPC1 translocates calcium from the extracellular region to the cytosol IEA Gallus gallus 29108 R-GGA-210420 https://reactome.org/PathwayBrowser/#/R-GGA-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Gallus gallus 29108 R-GGA-2132064 https://reactome.org/PathwayBrowser/#/R-GGA-2132064 Antigen bound antibody interacts with C1complement complex TAS Gallus gallus 29108 R-GGA-2132065 https://reactome.org/PathwayBrowser/#/R-GGA-2132065 C1r activates C1s component within C1 complement complex IEA Gallus gallus 29108 R-GGA-2132122 https://reactome.org/PathwayBrowser/#/R-GGA-2132122 Activation of C1r within the C1complement complex IEA Gallus gallus 29108 R-GGA-2132187 https://reactome.org/PathwayBrowser/#/R-GGA-2132187 MBL or ficolin binds an oligosaccharide pattern on the target cell surface TAS Gallus gallus 29108 R-GGA-2132206 https://reactome.org/PathwayBrowser/#/R-GGA-2132206 MASPs activation TAS Gallus gallus 29108 R-GGA-2132222 https://reactome.org/PathwayBrowser/#/R-GGA-2132222 Cleavage of factor B to form classical C3 convertase TAS Gallus gallus 29108 R-GGA-2132233 https://reactome.org/PathwayBrowser/#/R-GGA-2132233 Proteolytic cleavage of complement factor C4 TAS Gallus gallus 29108 R-GGA-2160884 https://reactome.org/PathwayBrowser/#/R-GGA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Gallus gallus 29108 R-GGA-2160892 https://reactome.org/PathwayBrowser/#/R-GGA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Gallus gallus 29108 R-GGA-2161768 https://reactome.org/PathwayBrowser/#/R-GGA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Gallus gallus 29108 R-GGA-2161907 https://reactome.org/PathwayBrowser/#/R-GGA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Gallus gallus 29108 R-GGA-2161917 https://reactome.org/PathwayBrowser/#/R-GGA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Gallus gallus 29108 R-GGA-2248891 https://reactome.org/PathwayBrowser/#/R-GGA-2248891 M6PR transports activated ARSA to the lysosome IEA Gallus gallus 29108 R-GGA-2424243 https://reactome.org/PathwayBrowser/#/R-GGA-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Gallus gallus 29108 R-GGA-2514867 https://reactome.org/PathwayBrowser/#/R-GGA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Gallus gallus 29108 R-GGA-2581474 https://reactome.org/PathwayBrowser/#/R-GGA-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Gallus gallus 29108 R-GGA-2586748 https://reactome.org/PathwayBrowser/#/R-GGA-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ IEA Gallus gallus 29108 R-GGA-264976 https://reactome.org/PathwayBrowser/#/R-GGA-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Gallus gallus 29108 R-GGA-265153 https://reactome.org/PathwayBrowser/#/R-GGA-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Gallus gallus 29108 R-GGA-265296 https://reactome.org/PathwayBrowser/#/R-GGA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Gallus gallus 29108 R-GGA-265301 https://reactome.org/PathwayBrowser/#/R-GGA-265301 Corticotropin cleavage from POMC IEA Gallus gallus 29108 R-GGA-265645 https://reactome.org/PathwayBrowser/#/R-GGA-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Gallus gallus 29108 R-GGA-266050 https://reactome.org/PathwayBrowser/#/R-GGA-266050 LTA4 is converted to LTC4 by LTC4S IEA Gallus gallus 29108 R-GGA-266051 https://reactome.org/PathwayBrowser/#/R-GGA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Gallus gallus 29108 R-GGA-2684901 https://reactome.org/PathwayBrowser/#/R-GGA-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Gallus gallus 29108 R-GGA-2685505 https://reactome.org/PathwayBrowser/#/R-GGA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Gallus gallus 29108 R-GGA-2730664 https://reactome.org/PathwayBrowser/#/R-GGA-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Gallus gallus 29108 R-GGA-2730849 https://reactome.org/PathwayBrowser/#/R-GGA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Gallus gallus 29108 R-GGA-2730867 https://reactome.org/PathwayBrowser/#/R-GGA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Gallus gallus 29108 R-GGA-2730872 https://reactome.org/PathwayBrowser/#/R-GGA-2730872 Activation of Calcineurin IEA Gallus gallus 29108 R-GGA-2744242 https://reactome.org/PathwayBrowser/#/R-GGA-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Gallus gallus 29108 R-GGA-2744361 https://reactome.org/PathwayBrowser/#/R-GGA-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Gallus gallus 29108 R-GGA-2855054 https://reactome.org/PathwayBrowser/#/R-GGA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Gallus gallus 29108 R-GGA-2855125 https://reactome.org/PathwayBrowser/#/R-GGA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Gallus gallus 29108 R-GGA-3229181 https://reactome.org/PathwayBrowser/#/R-GGA-3229181 CALM1:Ca2+ binds CNG channel IEA Gallus gallus 29108 R-GGA-3295579 https://reactome.org/PathwayBrowser/#/R-GGA-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Gallus gallus 29108 R-GGA-354066 https://reactome.org/PathwayBrowser/#/R-GGA-354066 Translocation of PTK2 to Focal complexes IEA Gallus gallus 29108 R-GGA-354073 https://reactome.org/PathwayBrowser/#/R-GGA-354073 Autophosphorylation of PTK2 at Y397 IEA Gallus gallus 29108 R-GGA-354087 https://reactome.org/PathwayBrowser/#/R-GGA-354087 Recruitment of GRB2 to p-PTK2 IEA Gallus gallus 29108 R-GGA-354124 https://reactome.org/PathwayBrowser/#/R-GGA-354124 Phosphorylation of pPTK2 by SRC IEA Gallus gallus 29108 R-GGA-354149 https://reactome.org/PathwayBrowser/#/R-GGA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Gallus gallus 29108 R-GGA-354165 https://reactome.org/PathwayBrowser/#/R-GGA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Gallus gallus 29108 R-GGA-354173 https://reactome.org/PathwayBrowser/#/R-GGA-354173 Activation of Rap1 by cytosolic GEFs IEA Gallus gallus 29108 R-GGA-372448 https://reactome.org/PathwayBrowser/#/R-GGA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Gallus gallus 29108 R-GGA-372693 https://reactome.org/PathwayBrowser/#/R-GGA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Gallus gallus 29108 R-GGA-372697 https://reactome.org/PathwayBrowser/#/R-GGA-372697 Crk binding to p130cas IEA Gallus gallus 29108 R-GGA-372705 https://reactome.org/PathwayBrowser/#/R-GGA-372705 Recruitment of BCAR1 to PTK2 complex IEA Gallus gallus 29108 R-GGA-377640 https://reactome.org/PathwayBrowser/#/R-GGA-377640 Autophosphorylation of SRC IEA Gallus gallus 29108 R-GGA-377641 https://reactome.org/PathwayBrowser/#/R-GGA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Gallus gallus 29108 R-GGA-377643 https://reactome.org/PathwayBrowser/#/R-GGA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Gallus gallus 29108 R-GGA-377644 https://reactome.org/PathwayBrowser/#/R-GGA-377644 Release of CSK from SRC IEA Gallus gallus 29108 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 29108 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 29108 R-GGA-3827958 https://reactome.org/PathwayBrowser/#/R-GGA-3827958 E-cadherin degradation by MMP9, KLK7 IEA Gallus gallus 29108 R-GGA-389463 https://reactome.org/PathwayBrowser/#/R-GGA-389463 Proteinase-activated receptors can bind thrombin IEA Gallus gallus 29108 R-GGA-390593 https://reactome.org/PathwayBrowser/#/R-GGA-390593 ATP Hydrolysis By Myosin IEA Gallus gallus 29108 R-GGA-390595 https://reactome.org/PathwayBrowser/#/R-GGA-390595 Calcium Binds Troponin-C IEA Gallus gallus 29108 R-GGA-390597 https://reactome.org/PathwayBrowser/#/R-GGA-390597 Release Of ADP From Myosin IEA Gallus gallus 29108 R-GGA-390598 https://reactome.org/PathwayBrowser/#/R-GGA-390598 Myosin Binds ATP IEA Gallus gallus 29108 R-GGA-399712 https://reactome.org/PathwayBrowser/#/R-GGA-399712 Activation of Ca permeable AMPA receptors IEA Gallus gallus 29108 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus 29108 R-GGA-418309 https://reactome.org/PathwayBrowser/#/R-GGA-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Gallus gallus 29108 R-GGA-418365 https://reactome.org/PathwayBrowser/#/R-GGA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Gallus gallus 29108 R-GGA-419001 https://reactome.org/PathwayBrowser/#/R-GGA-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Gallus gallus 29108 R-GGA-420724 https://reactome.org/PathwayBrowser/#/R-GGA-420724 CASR binds Ca2+ IEA Gallus gallus 29108 R-GGA-420739 https://reactome.org/PathwayBrowser/#/R-GGA-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Gallus gallus 29108 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus 29108 R-GGA-422021 https://reactome.org/PathwayBrowser/#/R-GGA-422021 PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin IEA Gallus gallus 29108 R-GGA-4224014 https://reactome.org/PathwayBrowser/#/R-GGA-4224014 E-cadherin degradation by ADAM10, ADAM15 IEA Gallus gallus 29108 R-GGA-425661 https://reactome.org/PathwayBrowser/#/R-GGA-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Gallus gallus 29108 R-GGA-425678 https://reactome.org/PathwayBrowser/#/R-GGA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Gallus gallus 29108 R-GGA-426223 https://reactome.org/PathwayBrowser/#/R-GGA-426223 Cation influx mediated by TRPC3/6/7 IEA Gallus gallus 29108 R-GGA-427910 https://reactome.org/PathwayBrowser/#/R-GGA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Gallus gallus 29108 R-GGA-428262 https://reactome.org/PathwayBrowser/#/R-GGA-428262 ACER3 hydrolyzes phytoceramide IEA Gallus gallus 29108 R-GGA-429016 https://reactome.org/PathwayBrowser/#/R-GGA-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Gallus gallus 29108 R-GGA-429415 https://reactome.org/PathwayBrowser/#/R-GGA-429415 SYK binds to integrin alphaIIb beta3 IEA Gallus gallus 29108 R-GGA-429441 https://reactome.org/PathwayBrowser/#/R-GGA-429441 SYK activation by SRC IEA Gallus gallus 29108 R-GGA-429529 https://reactome.org/PathwayBrowser/#/R-GGA-429529 Thrombin binding to GP1b:IX:V IEA Gallus gallus 29108 R-GGA-432164 https://reactome.org/PathwayBrowser/#/R-GGA-432164 Ca2+ influx into the post-synaptic cell IEA Gallus gallus 29108 R-GGA-4332358 https://reactome.org/PathwayBrowser/#/R-GGA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Gallus gallus 29108 R-GGA-4332359 https://reactome.org/PathwayBrowser/#/R-GGA-4332359 Active calmodulin binds CAMK2 IEA Gallus gallus 29108 R-GGA-4332363 https://reactome.org/PathwayBrowser/#/R-GGA-4332363 Autophosphorylation and activation of CAMK2 IEA Gallus gallus 29108 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus 29108 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus 29108 R-GGA-445700 https://reactome.org/PathwayBrowser/#/R-GGA-445700 Myosin Binds ATP IEA Gallus gallus 29108 R-GGA-445704 https://reactome.org/PathwayBrowser/#/R-GGA-445704 Calcium Binds Caldesmon IEA Gallus gallus 29108 R-GGA-445705 https://reactome.org/PathwayBrowser/#/R-GGA-445705 Release Of ADP From Myosin IEA Gallus gallus 29108 R-GGA-445797 https://reactome.org/PathwayBrowser/#/R-GGA-445797 MYLK (MLCK) Active Calmodulin Binding IEA Gallus gallus 29108 R-GGA-445813 https://reactome.org/PathwayBrowser/#/R-GGA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Gallus gallus 29108 R-GGA-451311 https://reactome.org/PathwayBrowser/#/R-GGA-451311 Activation of Ca-permeable Kainate receptors IEA Gallus gallus 29108 R-GGA-4551451 https://reactome.org/PathwayBrowser/#/R-GGA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Gallus gallus 29108 R-GGA-4551465 https://reactome.org/PathwayBrowser/#/R-GGA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Gallus gallus 29108 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 29108 R-GGA-5218813 https://reactome.org/PathwayBrowser/#/R-GGA-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Gallus gallus 29108 R-GGA-5218823 https://reactome.org/PathwayBrowser/#/R-GGA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Gallus gallus 29108 R-GGA-5223304 https://reactome.org/PathwayBrowser/#/R-GGA-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Gallus gallus 29108 R-GGA-5333671 https://reactome.org/PathwayBrowser/#/R-GGA-5333671 CLCAs self cleave IEA Gallus gallus 29108 R-GGA-5333678 https://reactome.org/PathwayBrowser/#/R-GGA-5333678 CPNEs bind PL IEA Gallus gallus 29108 R-GGA-5577213 https://reactome.org/PathwayBrowser/#/R-GGA-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Gallus gallus 29108 R-GGA-5578883 https://reactome.org/PathwayBrowser/#/R-GGA-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Gallus gallus 29108 R-GGA-5591040 https://reactome.org/PathwayBrowser/#/R-GGA-5591040 Activated protein C cleaves Factor Va intermediate form for Factor Va IEA Gallus gallus 29108 R-GGA-5591052 https://reactome.org/PathwayBrowser/#/R-GGA-5591052 PROCR binds Protein C IEA Gallus gallus 29108 R-GGA-5602080 https://reactome.org/PathwayBrowser/#/R-GGA-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Gallus gallus 29108 R-GGA-5603467 https://reactome.org/PathwayBrowser/#/R-GGA-5603467 Activated protein C is released from PROCR IEA Gallus gallus 29108 R-GGA-5604929 https://reactome.org/PathwayBrowser/#/R-GGA-5604929 Activated protein C binds Protein S IEA Gallus gallus 29108 R-GGA-5606996 https://reactome.org/PathwayBrowser/#/R-GGA-5606996 Soluble PROCR binds activated protein C IEA Gallus gallus 29108 R-GGA-5607002 https://reactome.org/PathwayBrowser/#/R-GGA-5607002 Activated protein C cleaves factor VIIIa IEA Gallus gallus 29108 R-GGA-5607058 https://reactome.org/PathwayBrowser/#/R-GGA-5607058 Activated protein C:PROCR binds F2R IEA Gallus gallus 29108 R-GGA-5626316 https://reactome.org/PathwayBrowser/#/R-GGA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Gallus gallus 29108 R-GGA-5626507 https://reactome.org/PathwayBrowser/#/R-GGA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Gallus gallus 29108 R-GGA-5626549 https://reactome.org/PathwayBrowser/#/R-GGA-5626549 IQGAPs bind CALM1 IEA Gallus gallus 29108 R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus 29108 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus 29108 R-GGA-5672969 https://reactome.org/PathwayBrowser/#/R-GGA-5672969 Phosphorylation of RAF IEA Gallus gallus 29108 R-GGA-5672972 https://reactome.org/PathwayBrowser/#/R-GGA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Gallus gallus 29108 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 29108 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 29108 R-GGA-5672980 https://reactome.org/PathwayBrowser/#/R-GGA-5672980 Dissociation of RAS:RAF complex IEA Gallus gallus 29108 R-GGA-5694018 https://reactome.org/PathwayBrowser/#/R-GGA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Gallus gallus 29108 R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 29108 R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 29108 R-GGA-622326 https://reactome.org/PathwayBrowser/#/R-GGA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Gallus gallus 29108 R-GGA-629595 https://reactome.org/PathwayBrowser/#/R-GGA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 29108 R-GGA-6798474 https://reactome.org/PathwayBrowser/#/R-GGA-6798474 S100A8:S100A9 binds Zn2+ IEA Gallus gallus 29108 R-GGA-6798489 https://reactome.org/PathwayBrowser/#/R-GGA-6798489 S100A7 or S100A7A binds Zn2+ IEA Gallus gallus 29108 R-GGA-6798528 https://reactome.org/PathwayBrowser/#/R-GGA-6798528 S100A8:S100A9 binds Mn2+ IEA Gallus gallus 29108 R-GGA-6805943 https://reactome.org/PathwayBrowser/#/R-GGA-6805943 S100A1 binds TLR4:LY96 IEA Gallus gallus 29108 R-GGA-71181 https://reactome.org/PathwayBrowser/#/R-GGA-71181 FAH cleaves 4FAA IEA Gallus gallus 29108 R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus 29108 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 29108 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 29108 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 29108 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 29108 R-GGA-74948 https://reactome.org/PathwayBrowser/#/R-GGA-74948 PP2A dephosphorylates p-RHO to RHO IEA Gallus gallus 29108 R-GGA-8850846 https://reactome.org/PathwayBrowser/#/R-GGA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Gallus gallus 29108 R-GGA-8850854 https://reactome.org/PathwayBrowser/#/R-GGA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Gallus gallus 29108 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 29108 R-GGA-8851110 https://reactome.org/PathwayBrowser/#/R-GGA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Gallus gallus 29108 R-GGA-8851129 https://reactome.org/PathwayBrowser/#/R-GGA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Gallus gallus 29108 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 29108 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 29108 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 29108 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 29108 R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 29108 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 29108 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 29108 R-GGA-8852509 https://reactome.org/PathwayBrowser/#/R-GGA-8852509 CL-LK binds carbohydrates on target cell surface IEA Gallus gallus 29108 R-GGA-8852716 https://reactome.org/PathwayBrowser/#/R-GGA-8852716 Thrombin, ELANE cleave C5 IEA Gallus gallus 29108 R-GGA-8857662 https://reactome.org/PathwayBrowser/#/R-GGA-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Gallus gallus 29108 R-GGA-8862771 https://reactome.org/PathwayBrowser/#/R-GGA-8862771 PLA2G2A binds bacterial phospholipids IEA Gallus gallus 29108 R-GGA-8878787 https://reactome.org/PathwayBrowser/#/R-GGA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Gallus gallus 29108 R-GGA-8932633 https://reactome.org/PathwayBrowser/#/R-GGA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Gallus gallus 29108 R-GGA-8934446 https://reactome.org/PathwayBrowser/#/R-GGA-8934446 Activated PKC phosphorylates SHC1 IEA Gallus gallus 29108 R-GGA-8949178 https://reactome.org/PathwayBrowser/#/R-GGA-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Gallus gallus 29108 R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 29108 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 29108 R-GGA-9015379 https://reactome.org/PathwayBrowser/#/R-GGA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Gallus gallus 29108 R-GGA-936883 https://reactome.org/PathwayBrowser/#/R-GGA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Gallus gallus 29108 R-GGA-9603302 https://reactome.org/PathwayBrowser/#/R-GGA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Gallus gallus 29108 R-GGA-9619376 https://reactome.org/PathwayBrowser/#/R-GGA-9619376 CAMK1 binds calmodulin IEA Gallus gallus 29108 R-GGA-9626848 https://reactome.org/PathwayBrowser/#/R-GGA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Gallus gallus 29108 R-GGA-9653585 https://reactome.org/PathwayBrowser/#/R-GGA-9653585 S-Farn-Me KRAS4B binds calmodulin IEA Gallus gallus 29108 R-GGA-9654521 https://reactome.org/PathwayBrowser/#/R-GGA-9654521 Calmodulin dissociates KRAS4B from the plasma membrane IEA Gallus gallus 29108 R-GGA-9654525 https://reactome.org/PathwayBrowser/#/R-GGA-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ IEA Gallus gallus 29108 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus 29108 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus 29108 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 29108 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus 29108 R-GGA-9659568 https://reactome.org/PathwayBrowser/#/R-GGA-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Gallus gallus 29108 R-GGA-9701055 https://reactome.org/PathwayBrowser/#/R-GGA-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Gallus gallus 29108 R-GGA-9701141 https://reactome.org/PathwayBrowser/#/R-GGA-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Gallus gallus 29108 R-GGA-9707186 https://reactome.org/PathwayBrowser/#/R-GGA-9707186 ALOX5 binds ALOX5 inhibitors IEA Gallus gallus 29108 R-GGA-9708859 https://reactome.org/PathwayBrowser/#/R-GGA-9708859 Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it IEA Gallus gallus 29108 R-GGA-9756177 https://reactome.org/PathwayBrowser/#/R-GGA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Gallus gallus 29108 R-GGA-9840949 https://reactome.org/PathwayBrowser/#/R-GGA-9840949 ARSA removes sulfate from SM3 IEA Gallus gallus 29108 R-GGA-9853499 https://reactome.org/PathwayBrowser/#/R-GGA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 29108 R-GGA-9853512 https://reactome.org/PathwayBrowser/#/R-GGA-9853512 DLST transfers succinyl to CoA IEA Gallus gallus 29108 R-HSA-111881 https://reactome.org/PathwayBrowser/#/R-HSA-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase TAS Homo sapiens 29108 R-HSA-111883 https://reactome.org/PathwayBrowser/#/R-HSA-111883 Hydrolysis of phosphatidylcholine TAS Homo sapiens 29108 R-HSA-111912 https://reactome.org/PathwayBrowser/#/R-HSA-111912 CaMK4 phosphorylates CREB1 IEA Homo sapiens 29108 R-HSA-111913 https://reactome.org/PathwayBrowser/#/R-HSA-111913 Calmodulin binds CAMK4 IEA Homo sapiens 29108 R-HSA-111915 https://reactome.org/PathwayBrowser/#/R-HSA-111915 CAMK4 autophosphorylates TAS Homo sapiens 29108 R-HSA-111930 https://reactome.org/PathwayBrowser/#/R-HSA-111930 Adenylate cyclase produces cAMP TAS Homo sapiens 29108 R-HSA-111956 https://reactome.org/PathwayBrowser/#/R-HSA-111956 Calmodulin activates Cam-PDE 1 TAS Homo sapiens 29108 R-HSA-111966 https://reactome.org/PathwayBrowser/#/R-HSA-111966 GRK2 binds CALM1:4Ca2+ TAS Homo sapiens 29108 R-HSA-111970 https://reactome.org/PathwayBrowser/#/R-HSA-111970 PKC phosphorylates GRK2 TAS Homo sapiens 29108 R-HSA-112333 https://reactome.org/PathwayBrowser/#/R-HSA-112333 SRC autophosphorylation is positively regulated by InlA-bound CDH1 TAS Homo sapiens 29108 R-HSA-114553 https://reactome.org/PathwayBrowser/#/R-HSA-114553 Activation of conventional Protein Kinase C TAS Homo sapiens 29108 R-HSA-114683 https://reactome.org/PathwayBrowser/#/R-HSA-114683 Phosphorylation of Platelet Sec-1 TAS Homo sapiens 29108 R-HSA-114684 https://reactome.org/PathwayBrowser/#/R-HSA-114684 Phosphorylation of Syntaxin-4 TAS Homo sapiens 29108 R-HSA-114697 https://reactome.org/PathwayBrowser/#/R-HSA-114697 Activated thrombin (factor IIa) cleaves PAR3,4, activating them TAS Homo sapiens 29108 R-HSA-1168373 https://reactome.org/PathwayBrowser/#/R-HSA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine TAS Homo sapiens 29108 R-HSA-1168376 https://reactome.org/PathwayBrowser/#/R-HSA-1168376 STIM1 oligomerizes TAS Homo sapiens 29108 R-HSA-1168635 https://reactome.org/PathwayBrowser/#/R-HSA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 TAS Homo sapiens 29108 R-HSA-1183128 https://reactome.org/PathwayBrowser/#/R-HSA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins TAS Homo sapiens 29108 R-HSA-139854 https://reactome.org/PathwayBrowser/#/R-HSA-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol TAS Homo sapiens 29108 R-HSA-139855 https://reactome.org/PathwayBrowser/#/R-HSA-139855 P2X1-mediated entry of Ca++ from plasma TAS Homo sapiens 29108 R-HSA-139941 https://reactome.org/PathwayBrowser/#/R-HSA-139941 Binding of IP3 to IP3 receptor TAS Homo sapiens 29108 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 29108 R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 29108 R-HSA-140686 https://reactome.org/PathwayBrowser/#/R-HSA-140686 factor Va + factor Xa -> Va:Xa complex (prothrombinase) TAS Homo sapiens 29108 R-HSA-140696 https://reactome.org/PathwayBrowser/#/R-HSA-140696 factor V -> factor Va + factor V activation peptide TAS Homo sapiens 29108 R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 29108 R-HSA-140736 https://reactome.org/PathwayBrowser/#/R-HSA-140736 factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) TAS Homo sapiens 29108 R-HSA-140748 https://reactome.org/PathwayBrowser/#/R-HSA-140748 tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex TAS Homo sapiens 29108 R-HSA-140769 https://reactome.org/PathwayBrowser/#/R-HSA-140769 factor VII -> factor VIIa TAS Homo sapiens 29108 R-HSA-140777 https://reactome.org/PathwayBrowser/#/R-HSA-140777 factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) TAS Homo sapiens 29108 R-HSA-140783 https://reactome.org/PathwayBrowser/#/R-HSA-140783 tissue factor (TF) + factor VII (F7) -> TF:F7 complex TAS Homo sapiens 29108 R-HSA-140791 https://reactome.org/PathwayBrowser/#/R-HSA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin TAS Homo sapiens 29108 R-HSA-140823 https://reactome.org/PathwayBrowser/#/R-HSA-140823 factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) TAS Homo sapiens 29108 R-HSA-140825 https://reactome.org/PathwayBrowser/#/R-HSA-140825 TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa TAS Homo sapiens 29108 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 29108 R-HSA-140847 https://reactome.org/PathwayBrowser/#/R-HSA-140847 factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain TAS Homo sapiens 29108 R-HSA-140851 https://reactome.org/PathwayBrowser/#/R-HSA-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ TAS Homo sapiens 29108 R-HSA-140870 https://reactome.org/PathwayBrowser/#/R-HSA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin TAS Homo sapiens 29108 R-HSA-140872 https://reactome.org/PathwayBrowser/#/R-HSA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators TAS Homo sapiens 29108 R-HSA-141026 https://reactome.org/PathwayBrowser/#/R-HSA-141026 Activated protein C cleaves factor Va to factor Vi intermediate form TAS Homo sapiens 29108 R-HSA-141040 https://reactome.org/PathwayBrowser/#/R-HSA-141040 Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C TAS Homo sapiens 29108 R-HSA-141046 https://reactome.org/PathwayBrowser/#/R-HSA-141046 activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin TAS Homo sapiens 29108 R-HSA-1454843 https://reactome.org/PathwayBrowser/#/R-HSA-1454843 E-cadherin degradation by MMP3, MMP7 and plasmin. IEA Homo sapiens 29108 R-HSA-1482604 https://reactome.org/PathwayBrowser/#/R-HSA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) TAS Homo sapiens 29108 R-HSA-1482612 https://reactome.org/PathwayBrowser/#/R-HSA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 29108 R-HSA-1482656 https://reactome.org/PathwayBrowser/#/R-HSA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] TAS Homo sapiens 29108 R-HSA-1482679 https://reactome.org/PathwayBrowser/#/R-HSA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A TAS Homo sapiens 29108 R-HSA-1482685 https://reactome.org/PathwayBrowser/#/R-HSA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 29108 R-HSA-1482759 https://reactome.org/PathwayBrowser/#/R-HSA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) TAS Homo sapiens 29108 R-HSA-1482771 https://reactome.org/PathwayBrowser/#/R-HSA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] TAS Homo sapiens 29108 R-HSA-1482776 https://reactome.org/PathwayBrowser/#/R-HSA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A TAS Homo sapiens 29108 R-HSA-1482816 https://reactome.org/PathwayBrowser/#/R-HSA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] TAS Homo sapiens 29108 R-HSA-1482825 https://reactome.org/PathwayBrowser/#/R-HSA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] TAS Homo sapiens 29108 R-HSA-1482828 https://reactome.org/PathwayBrowser/#/R-HSA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] TAS Homo sapiens 29108 R-HSA-1482856 https://reactome.org/PathwayBrowser/#/R-HSA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] TAS Homo sapiens 29108 R-HSA-1482862 https://reactome.org/PathwayBrowser/#/R-HSA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] TAS Homo sapiens 29108 R-HSA-1482868 https://reactome.org/PathwayBrowser/#/R-HSA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] TAS Homo sapiens 29108 R-HSA-1482884 https://reactome.org/PathwayBrowser/#/R-HSA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] TAS Homo sapiens 29108 R-HSA-1482887 https://reactome.org/PathwayBrowser/#/R-HSA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] TAS Homo sapiens 29108 R-HSA-1482897 https://reactome.org/PathwayBrowser/#/R-HSA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] TAS Homo sapiens 29108 R-HSA-1482900 https://reactome.org/PathwayBrowser/#/R-HSA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] TAS Homo sapiens 29108 R-HSA-1482907 https://reactome.org/PathwayBrowser/#/R-HSA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A TAS Homo sapiens 29108 R-HSA-1497784 https://reactome.org/PathwayBrowser/#/R-HSA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle TAS Homo sapiens 29108 R-HSA-1497796 https://reactome.org/PathwayBrowser/#/R-HSA-1497796 BH2 binding can lead to eNOS uncoupling TAS Homo sapiens 29108 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 29108 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 29108 R-HSA-158164 https://reactome.org/PathwayBrowser/#/R-HSA-158164 factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) TAS Homo sapiens 29108 R-HSA-158278 https://reactome.org/PathwayBrowser/#/R-HSA-158278 factor VIIIa + factor IXa -> factor VIIIa:factor IXa TAS Homo sapiens 29108 R-HSA-158333 https://reactome.org/PathwayBrowser/#/R-HSA-158333 factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) TAS Homo sapiens 29108 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 29108 R-HSA-1602368 https://reactome.org/PathwayBrowser/#/R-HSA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] TAS Homo sapiens 29108 R-HSA-1602374 https://reactome.org/PathwayBrowser/#/R-HSA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] TAS Homo sapiens 29108 R-HSA-1602377 https://reactome.org/PathwayBrowser/#/R-HSA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] TAS Homo sapiens 29108 R-HSA-1602398 https://reactome.org/PathwayBrowser/#/R-HSA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] TAS Homo sapiens 29108 R-HSA-1602417 https://reactome.org/PathwayBrowser/#/R-HSA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] TAS Homo sapiens 29108 R-HSA-1602446 https://reactome.org/PathwayBrowser/#/R-HSA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] TAS Homo sapiens 29108 R-HSA-1606789 https://reactome.org/PathwayBrowser/#/R-HSA-1606789 ARSB hydrolyses DS TAS Homo sapiens 29108 R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 29108 R-HSA-1606839 https://reactome.org/PathwayBrowser/#/R-HSA-1606839 ARSC hydrolyzes steroid sulfates TAS Homo sapiens 29108 R-HSA-1614362 https://reactome.org/PathwayBrowser/#/R-HSA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases TAS Homo sapiens 29108 R-HSA-166072 https://reactome.org/PathwayBrowser/#/R-HSA-166072 MyD88 forms a complex with TIRAP:activated TLR2/4 TAS Homo sapiens 29108 R-HSA-166082 https://reactome.org/PathwayBrowser/#/R-HSA-166082 IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex TAS Homo sapiens 29108 R-HSA-166091 https://reactome.org/PathwayBrowser/#/R-HSA-166091 IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex TAS Homo sapiens 29108 R-HSA-166119 https://reactome.org/PathwayBrowser/#/R-HSA-166119 First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal TAS Homo sapiens 29108 R-HSA-166284 https://reactome.org/PathwayBrowser/#/R-HSA-166284 Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP TAS Homo sapiens 29108 R-HSA-166286 https://reactome.org/PathwayBrowser/#/R-HSA-166286 Multiple IRAK1 autophosphorylation steps TAS Homo sapiens 29108 R-HSA-166362 https://reactome.org/PathwayBrowser/#/R-HSA-166362 Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 29108 R-HSA-166363 https://reactome.org/PathwayBrowser/#/R-HSA-166363 TRAF6 binds to hp- IRAK1 TAS Homo sapiens 29108 R-HSA-166721 https://reactome.org/PathwayBrowser/#/R-HSA-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa TAS Homo sapiens 29108 R-HSA-166726 https://reactome.org/PathwayBrowser/#/R-HSA-166726 Activation of MASPs TAS Homo sapiens 29108 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens 29108 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens 29108 R-HSA-1675928 https://reactome.org/PathwayBrowser/#/R-HSA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane TAS Homo sapiens 29108 R-HSA-1675939 https://reactome.org/PathwayBrowser/#/R-HSA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane TAS Homo sapiens 29108 R-HSA-1675961 https://reactome.org/PathwayBrowser/#/R-HSA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane TAS Homo sapiens 29108 R-HSA-1676024 https://reactome.org/PathwayBrowser/#/R-HSA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane TAS Homo sapiens 29108 R-HSA-1676109 https://reactome.org/PathwayBrowser/#/R-HSA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane TAS Homo sapiens 29108 R-HSA-1676206 https://reactome.org/PathwayBrowser/#/R-HSA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane TAS Homo sapiens 29108 R-HSA-1678650 https://reactome.org/PathwayBrowser/#/R-HSA-1678650 IDS hydrolyses Heparan sulfate chain(5) TAS Homo sapiens 29108 R-HSA-169683 https://reactome.org/PathwayBrowser/#/R-HSA-169683 IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol IEA Homo sapiens 29108 R-HSA-173626 https://reactome.org/PathwayBrowser/#/R-HSA-173626 Activation of C1r TAS Homo sapiens 29108 R-HSA-1793182 https://reactome.org/PathwayBrowser/#/R-HSA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) TAS Homo sapiens 29108 R-HSA-1793207 https://reactome.org/PathwayBrowser/#/R-HSA-1793207 ARSB hydrolyses C4S/C6S chains TAS Homo sapiens 29108 R-HSA-1855153 https://reactome.org/PathwayBrowser/#/R-HSA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol TAS Homo sapiens 29108 R-HSA-1855177 https://reactome.org/PathwayBrowser/#/R-HSA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane TAS Homo sapiens 29108 R-HSA-1855214 https://reactome.org/PathwayBrowser/#/R-HSA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane TAS Homo sapiens 29108 R-HSA-1855221 https://reactome.org/PathwayBrowser/#/R-HSA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane TAS Homo sapiens 29108 R-HSA-187020 https://reactome.org/PathwayBrowser/#/R-HSA-187020 Part of pro-beta-NGF is processed to mature beta-NGF TAS Homo sapiens 29108 R-HSA-201783 https://reactome.org/PathwayBrowser/#/R-HSA-201783 Inactive catalytic PP2B is activated by the binding of calmodulin IEA Homo sapiens 29108 R-HSA-201787 https://reactome.org/PathwayBrowser/#/R-HSA-201787 PPP3 complex dephosphorylates DARPP-32 on Thr34 IEA Homo sapiens 29108 R-HSA-202110 https://reactome.org/PathwayBrowser/#/R-HSA-202110 eNOS:Caveolin-1 complex binds to CaM TAS Homo sapiens 29108 R-HSA-202111 https://reactome.org/PathwayBrowser/#/R-HSA-202111 AKT1 phosphorylates eNOS TAS Homo sapiens 29108 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 29108 R-HSA-202129 https://reactome.org/PathwayBrowser/#/R-HSA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex TAS Homo sapiens 29108 R-HSA-202137 https://reactome.org/PathwayBrowser/#/R-HSA-202137 AKT1 binds eNOS complex via HSP90 TAS Homo sapiens 29108 R-HSA-202144 https://reactome.org/PathwayBrowser/#/R-HSA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex TAS Homo sapiens 29108 R-HSA-2025882 https://reactome.org/PathwayBrowser/#/R-HSA-2025882 Calcineurin dephosphorylates NFATC1,2,3 IEA Homo sapiens 29108 R-HSA-2025890 https://reactome.org/PathwayBrowser/#/R-HSA-2025890 Calcineurin binds NFATC1,2,3 TAS Homo sapiens 29108 R-HSA-2089943 https://reactome.org/PathwayBrowser/#/R-HSA-2089943 TRPC1 translocates calcium from the extracellular region to the cytosol TAS Homo sapiens 29108 R-HSA-210420 https://reactome.org/PathwayBrowser/#/R-HSA-210420 Ca2+ influx through voltage gated Ca2+ channels TAS Homo sapiens 29108 R-HSA-210430 https://reactome.org/PathwayBrowser/#/R-HSA-210430 Release of L-Glutamate at the synapse TAS Homo sapiens 29108 R-HSA-2160884 https://reactome.org/PathwayBrowser/#/R-HSA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ TAS Homo sapiens 29108 R-HSA-2160892 https://reactome.org/PathwayBrowser/#/R-HSA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments TAS Homo sapiens 29108 R-HSA-2161768 https://reactome.org/PathwayBrowser/#/R-HSA-2161768 EXA4 is converted to EXC4 by LTC4S TAS Homo sapiens 29108 R-HSA-2161907 https://reactome.org/PathwayBrowser/#/R-HSA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 TAS Homo sapiens 29108 R-HSA-2161917 https://reactome.org/PathwayBrowser/#/R-HSA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 TAS Homo sapiens 29108 R-HSA-2201316 https://reactome.org/PathwayBrowser/#/R-HSA-2201316 Activated TLR2/4 interacts with MAL (TIRAP) TAS Homo sapiens 29108 R-HSA-2201322 https://reactome.org/PathwayBrowser/#/R-HSA-2201322 TIRAP is phosphorylated by BTK TAS Homo sapiens 29108 R-HSA-2248891 https://reactome.org/PathwayBrowser/#/R-HSA-2248891 M6PR transports activated ARSA to the lysosome TAS Homo sapiens 29108 R-HSA-2262743 https://reactome.org/PathwayBrowser/#/R-HSA-2262743 Defective IDS does not hydrolyse dermatan sulfate (Chebi:63517 chain) TAS Homo sapiens 29108 R-HSA-2262775 https://reactome.org/PathwayBrowser/#/R-HSA-2262775 Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 29108 R-HSA-2262777 https://reactome.org/PathwayBrowser/#/R-HSA-2262777 TRAF6 binds to p-IRAK2 TAS Homo sapiens 29108 R-HSA-2282889 https://reactome.org/PathwayBrowser/#/R-HSA-2282889 Defective ARSB does not hydrolyse C4S/C6S chains TAS Homo sapiens 29108 R-HSA-2316352 https://reactome.org/PathwayBrowser/#/R-HSA-2316352 SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane IEA Homo sapiens 29108 R-HSA-2424243 https://reactome.org/PathwayBrowser/#/R-HSA-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ TAS Homo sapiens 29108 R-HSA-2514867 https://reactome.org/PathwayBrowser/#/R-HSA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment TAS Homo sapiens 29108 R-HSA-2514891 https://reactome.org/PathwayBrowser/#/R-HSA-2514891 SLC24A1 exchanges 4Na+ for Ca2+, K+ IEA Homo sapiens 29108 R-HSA-2534206 https://reactome.org/PathwayBrowser/#/R-HSA-2534206 E-cadherin degradation by PS1:NCSTN (Gamma-secretase) IEA Homo sapiens 29108 R-HSA-2534260 https://reactome.org/PathwayBrowser/#/R-HSA-2534260 E-cadherin degradation by caspase-3 and calpain-1 IEA Homo sapiens 29108 R-HSA-2534359 https://reactome.org/PathwayBrowser/#/R-HSA-2534359 CatSper Channel Mediated Calcium Transport TAS Homo sapiens 29108 R-HSA-2559414 https://reactome.org/PathwayBrowser/#/R-HSA-2559414 Activated TLR2/4:TIRAP interacts with BTK TAS Homo sapiens 29108 R-HSA-2581474 https://reactome.org/PathwayBrowser/#/R-HSA-2581474 GRK1,4,7 phosphorylate MII to p-MII TAS Homo sapiens 29108 R-HSA-2586748 https://reactome.org/PathwayBrowser/#/R-HSA-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ TAS Homo sapiens 29108 R-HSA-264976 https://reactome.org/PathwayBrowser/#/R-HSA-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium TAS Homo sapiens 29108 R-HSA-265153 https://reactome.org/PathwayBrowser/#/R-HSA-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule TAS Homo sapiens 29108 R-HSA-265160 https://reactome.org/PathwayBrowser/#/R-HSA-265160 Insulin secretory granule translocates to cell cortex IEA Homo sapiens 29108 R-HSA-265166 https://reactome.org/PathwayBrowser/#/R-HSA-265166 Exocytosis of Insulin IEA Homo sapiens 29108 R-HSA-265296 https://reactome.org/PathwayBrowser/#/R-HSA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 TAS Homo sapiens 29108 R-HSA-265301 https://reactome.org/PathwayBrowser/#/R-HSA-265301 Corticotropin cleavage from POMC TAS Homo sapiens 29108 R-HSA-265645 https://reactome.org/PathwayBrowser/#/R-HSA-265645 Calcium Influx through Voltage-gated Calcium Channels TAS Homo sapiens 29108 R-HSA-266050 https://reactome.org/PathwayBrowser/#/R-HSA-266050 LTA4 is converted to LTC4 by LTC4S TAS Homo sapiens 29108 R-HSA-266051 https://reactome.org/PathwayBrowser/#/R-HSA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 TAS Homo sapiens 29108 R-HSA-2684901 https://reactome.org/PathwayBrowser/#/R-HSA-2684901 ANOs transport cytosolic Cl- to extracellular region TAS Homo sapiens 29108 R-HSA-2685505 https://reactome.org/PathwayBrowser/#/R-HSA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol TAS Homo sapiens 29108 R-HSA-2730664 https://reactome.org/PathwayBrowser/#/R-HSA-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol TAS Homo sapiens 29108 R-HSA-2730849 https://reactome.org/PathwayBrowser/#/R-HSA-2730849 Calcineurin binds and dephosphorylates NFAT TAS Homo sapiens 29108 R-HSA-2730867 https://reactome.org/PathwayBrowser/#/R-HSA-2730867 Translocation of CaN:CaM:NFAT to nucleus TAS Homo sapiens 29108 R-HSA-2730871 https://reactome.org/PathwayBrowser/#/R-HSA-2730871 RasGRP interacts with DAG and Ca2+ IEA Homo sapiens 29108 R-HSA-2730872 https://reactome.org/PathwayBrowser/#/R-HSA-2730872 Activation of Calcineurin TAS Homo sapiens 29108 R-HSA-2744242 https://reactome.org/PathwayBrowser/#/R-HSA-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region TAS Homo sapiens 29108 R-HSA-2744361 https://reactome.org/PathwayBrowser/#/R-HSA-2744361 BESTs transport cytosolic Cl- to extracellular region TAS Homo sapiens 29108 R-HSA-2855020 https://reactome.org/PathwayBrowser/#/R-HSA-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol TAS Homo sapiens 29108 R-HSA-2855054 https://reactome.org/PathwayBrowser/#/R-HSA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface TAS Homo sapiens 29108 R-HSA-2855077 https://reactome.org/PathwayBrowser/#/R-HSA-2855077 Ficolin-3 binds to molecular patterns on the target cell surface TAS Homo sapiens 29108 R-HSA-2855125 https://reactome.org/PathwayBrowser/#/R-HSA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface TAS Homo sapiens 29108 R-HSA-3229181 https://reactome.org/PathwayBrowser/#/R-HSA-3229181 CALM1:Ca2+ binds CNG channel TAS Homo sapiens 29108 R-HSA-3229213 https://reactome.org/PathwayBrowser/#/R-HSA-3229213 RCVRN:Ca2+ binds to and inhibits GRK1 IEA Homo sapiens 29108 R-HSA-3295579 https://reactome.org/PathwayBrowser/#/R-HSA-3295579 TRPs transport extracellular Ca2+ to cytosol TAS Homo sapiens 29108 R-HSA-354066 https://reactome.org/PathwayBrowser/#/R-HSA-354066 Translocation of PTK2 to Focal complexes TAS Homo sapiens 29108 R-HSA-354073 https://reactome.org/PathwayBrowser/#/R-HSA-354073 Autophosphorylation of PTK2 at Y397 TAS Homo sapiens 29108 R-HSA-354087 https://reactome.org/PathwayBrowser/#/R-HSA-354087 Recruitment of GRB2 to p-PTK2 TAS Homo sapiens 29108 R-HSA-354124 https://reactome.org/PathwayBrowser/#/R-HSA-354124 Phosphorylation of pPTK2 by SRC TAS Homo sapiens 29108 R-HSA-354149 https://reactome.org/PathwayBrowser/#/R-HSA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen TAS Homo sapiens 29108 R-HSA-354165 https://reactome.org/PathwayBrowser/#/R-HSA-354165 Interaction of SOS with GRB2 bound to FADK1 TAS Homo sapiens 29108 R-HSA-354173 https://reactome.org/PathwayBrowser/#/R-HSA-354173 Activation of Rap1 by cytosolic GEFs TAS Homo sapiens 29108 R-HSA-372448 https://reactome.org/PathwayBrowser/#/R-HSA-372448 SLC25A12,13 exchange L-Glu and L-Asp TAS Homo sapiens 29108 R-HSA-372693 https://reactome.org/PathwayBrowser/#/R-HSA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex TAS Homo sapiens 29108 R-HSA-372697 https://reactome.org/PathwayBrowser/#/R-HSA-372697 Crk binding to p130cas TAS Homo sapiens 29108 R-HSA-372705 https://reactome.org/PathwayBrowser/#/R-HSA-372705 Recruitment of BCAR1 to PTK2 complex TAS Homo sapiens 29108 R-HSA-377640 https://reactome.org/PathwayBrowser/#/R-HSA-377640 Autophosphorylation of SRC TAS Homo sapiens 29108 R-HSA-377641 https://reactome.org/PathwayBrowser/#/R-HSA-377641 Clustering of Integrin alphaIIb beta3 complexes TAS Homo sapiens 29108 R-HSA-377643 https://reactome.org/PathwayBrowser/#/R-HSA-377643 Dephosphorylation of inactive SRC by PTPB1 TAS Homo sapiens 29108 R-HSA-377644 https://reactome.org/PathwayBrowser/#/R-HSA-377644 Release of CSK from SRC TAS Homo sapiens 29108 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 29108 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 29108 R-HSA-381446 https://reactome.org/PathwayBrowser/#/R-HSA-381446 Thrombin proteolyzes IGF:IGFBP3:ALS TAS Homo sapiens 29108 R-HSA-381798 https://reactome.org/PathwayBrowser/#/R-HSA-381798 PCSK1 hydrolyzes Proglucagon to Glucagon-like Peptide-1 IEA Homo sapiens 29108 R-HSA-3827958 https://reactome.org/PathwayBrowser/#/R-HSA-3827958 E-cadherin degradation by MMP9, KLK7 TAS Homo sapiens 29108 R-HSA-389463 https://reactome.org/PathwayBrowser/#/R-HSA-389463 Proteinase-activated receptors can bind thrombin TAS Homo sapiens 29108 R-HSA-390593 https://reactome.org/PathwayBrowser/#/R-HSA-390593 ATP Hydrolysis By Myosin TAS Homo sapiens 29108 R-HSA-390595 https://reactome.org/PathwayBrowser/#/R-HSA-390595 Calcium Binds Troponin-C TAS Homo sapiens 29108 R-HSA-390597 https://reactome.org/PathwayBrowser/#/R-HSA-390597 Release Of ADP From Myosin TAS Homo sapiens 29108 R-HSA-390598 https://reactome.org/PathwayBrowser/#/R-HSA-390598 Myosin Binds ATP TAS Homo sapiens 29108 R-HSA-392831 https://reactome.org/PathwayBrowser/#/R-HSA-392831 Calcium and Diacylglycerol activate CalDAG-GEFs (RasGRPs) IEA Homo sapiens 29108 R-HSA-399712 https://reactome.org/PathwayBrowser/#/R-HSA-399712 Activation of Ca permeable AMPA receptors TAS Homo sapiens 29108 R-HSA-400492 https://reactome.org/PathwayBrowser/#/R-HSA-400492 PCSK1 hydrolyzes proGIP to GIP IEA Homo sapiens 29108 R-HSA-416639 https://reactome.org/PathwayBrowser/#/R-HSA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites TAS Homo sapiens 29108 R-HSA-418309 https://reactome.org/PathwayBrowser/#/R-HSA-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region TAS Homo sapiens 29108 R-HSA-418365 https://reactome.org/PathwayBrowser/#/R-HSA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen TAS Homo sapiens 29108 R-HSA-419001 https://reactome.org/PathwayBrowser/#/R-HSA-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin TAS Homo sapiens 29108 R-HSA-420724 https://reactome.org/PathwayBrowser/#/R-HSA-420724 CASR binds Ca2+ TAS Homo sapiens 29108 R-HSA-420739 https://reactome.org/PathwayBrowser/#/R-HSA-420739 GPRC6A can bind L-alpha amino acids and calcium TAS Homo sapiens 29108 R-HSA-421007 https://reactome.org/PathwayBrowser/#/R-HSA-421007 Endocytosis of Ca impermeable AMPA receptors TAS Homo sapiens 29108 R-HSA-422021 https://reactome.org/PathwayBrowser/#/R-HSA-422021 PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin TAS Homo sapiens 29108 R-HSA-4224014 https://reactome.org/PathwayBrowser/#/R-HSA-4224014 E-cadherin degradation by ADAM10, ADAM15 TAS Homo sapiens 29108 R-HSA-425661 https://reactome.org/PathwayBrowser/#/R-HSA-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ TAS Homo sapiens 29108 R-HSA-425678 https://reactome.org/PathwayBrowser/#/R-HSA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ TAS Homo sapiens 29108 R-HSA-425822 https://reactome.org/PathwayBrowser/#/R-HSA-425822 K+-independent Li+/Ca2+ exchanger transport TAS Homo sapiens 29108 R-HSA-426223 https://reactome.org/PathwayBrowser/#/R-HSA-426223 Cation influx mediated by TRPC3/6/7 TAS Homo sapiens 29108 R-HSA-427910 https://reactome.org/PathwayBrowser/#/R-HSA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen TAS Homo sapiens 29108 R-HSA-428262 https://reactome.org/PathwayBrowser/#/R-HSA-428262 ACER3 hydrolyzes phytoceramide TAS Homo sapiens 29108 R-HSA-429016 https://reactome.org/PathwayBrowser/#/R-HSA-429016 ALOX5 is phosphorylated by MAPKAP2 TAS Homo sapiens 29108 R-HSA-429415 https://reactome.org/PathwayBrowser/#/R-HSA-429415 SYK binds to integrin alphaIIb beta3 TAS Homo sapiens 29108 R-HSA-429441 https://reactome.org/PathwayBrowser/#/R-HSA-429441 SYK activation by SRC TAS Homo sapiens 29108 R-HSA-429529 https://reactome.org/PathwayBrowser/#/R-HSA-429529 Thrombin binding to GP1b:IX:V TAS Homo sapiens 29108 R-HSA-432164 https://reactome.org/PathwayBrowser/#/R-HSA-432164 Ca2+ influx into the post-synaptic cell TAS Homo sapiens 29108 R-HSA-4332358 https://reactome.org/PathwayBrowser/#/R-HSA-4332358 Dissociation of CaM and CAMK2 autophosphorylation TAS Homo sapiens 29108 R-HSA-4332359 https://reactome.org/PathwayBrowser/#/R-HSA-4332359 Active calmodulin binds CAMK2 TAS Homo sapiens 29108 R-HSA-4332363 https://reactome.org/PathwayBrowser/#/R-HSA-4332363 Autophosphorylation and activation of CAMK2 TAS Homo sapiens 29108 R-HSA-4332390 https://reactome.org/PathwayBrowser/#/R-HSA-4332390 Translocation and activation of PKC alpha in response to WNT signaling IEA Homo sapiens 29108 R-HSA-434798 https://reactome.org/PathwayBrowser/#/R-HSA-434798 CRAC translocates calcium from the extracellular region to the cytosol IEA Homo sapiens 29108 R-HSA-438037 https://reactome.org/PathwayBrowser/#/R-HSA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors TAS Homo sapiens 29108 R-HSA-4420052 https://reactome.org/PathwayBrowser/#/R-HSA-4420052 Decreasing cGMP concentration promotes intracellular Ca2+ release in response to WNT IEA Homo sapiens 29108 R-HSA-442715 https://reactome.org/PathwayBrowser/#/R-HSA-442715 Calmodulin-activated adenylate cyclases ADCY1 and ADCY8 generate cAMP IEA Homo sapiens 29108 R-HSA-442725 https://reactome.org/PathwayBrowser/#/R-HSA-442725 CaMKII binds activated calmodulin IEA Homo sapiens 29108 R-HSA-442732 https://reactome.org/PathwayBrowser/#/R-HSA-442732 NMDA-activated RASGRF1 activates RAS IEA Homo sapiens 29108 R-HSA-442749 https://reactome.org/PathwayBrowser/#/R-HSA-442749 CaMKK autophosphorylates in the nucleus TAS Homo sapiens 29108 R-HSA-442760 https://reactome.org/PathwayBrowser/#/R-HSA-442760 Activation of RasGRF IEA Homo sapiens 29108 R-HSA-444792 https://reactome.org/PathwayBrowser/#/R-HSA-444792 Calmodulin-bound CaMKII-gamma enters the nucleus IEA Homo sapiens 29108 R-HSA-445367 https://reactome.org/PathwayBrowser/#/R-HSA-445367 CaMKII binds activated NMDA receptor IEA Homo sapiens 29108 R-HSA-445699 https://reactome.org/PathwayBrowser/#/R-HSA-445699 ATP Hydrolysis By Myosin TAS Homo sapiens 29108 R-HSA-445700 https://reactome.org/PathwayBrowser/#/R-HSA-445700 Myosin Binds ATP TAS Homo sapiens 29108 R-HSA-445704 https://reactome.org/PathwayBrowser/#/R-HSA-445704 Calcium Binds Caldesmon TAS Homo sapiens 29108 R-HSA-445705 https://reactome.org/PathwayBrowser/#/R-HSA-445705 Release Of ADP From Myosin TAS Homo sapiens 29108 R-HSA-445797 https://reactome.org/PathwayBrowser/#/R-HSA-445797 MYLK (MLCK) Active Calmodulin Binding TAS Homo sapiens 29108 R-HSA-445813 https://reactome.org/PathwayBrowser/#/R-HSA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains TAS Homo sapiens 29108 R-HSA-451311 https://reactome.org/PathwayBrowser/#/R-HSA-451311 Activation of Ca-permeable Kainate receptors TAS Homo sapiens 29108 R-HSA-453337 https://reactome.org/PathwayBrowser/#/R-HSA-453337 glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP IEA Homo sapiens 29108 R-HSA-4551451 https://reactome.org/PathwayBrowser/#/R-HSA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling TAS Homo sapiens 29108 R-HSA-4551465 https://reactome.org/PathwayBrowser/#/R-HSA-4551465 Translocation of NFATC1:CaN:CaM to nucleus TAS Homo sapiens 29108 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 29108 R-HSA-5138432 https://reactome.org/PathwayBrowser/#/R-HSA-5138432 DVL2 is phosphorylated by PKC TAS Homo sapiens 29108 R-HSA-5210892 https://reactome.org/PathwayBrowser/#/R-HSA-5210892 cya and lef bind to pagA(197-794):ANTXR2 oligomer TAS Homo sapiens 29108 R-HSA-5210909 https://reactome.org/PathwayBrowser/#/R-HSA-5210909 ANTXR1-bound pagA(197-794) forms oligomers TAS Homo sapiens 29108 R-HSA-5210912 https://reactome.org/PathwayBrowser/#/R-HSA-5210912 Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) TAS Homo sapiens 29108 R-HSA-5210918 https://reactome.org/PathwayBrowser/#/R-HSA-5210918 pagA binds ANTXR2 TAS Homo sapiens 29108 R-HSA-5210921 https://reactome.org/PathwayBrowser/#/R-HSA-5210921 pagA binds ANTXR1 TAS Homo sapiens 29108 R-HSA-5210923 https://reactome.org/PathwayBrowser/#/R-HSA-5210923 cya and lef bind to pagA(197-794):ANTXR1 oligomer TAS Homo sapiens 29108 R-HSA-5210932 https://reactome.org/PathwayBrowser/#/R-HSA-5210932 ANTXR2-bound pagA(197-794) forms oligomers TAS Homo sapiens 29108 R-HSA-5210935 https://reactome.org/PathwayBrowser/#/R-HSA-5210935 Furin cleaves ANTXR1-bound pagA to yield pagA(197-794) TAS Homo sapiens 29108 R-HSA-5210943 https://reactome.org/PathwayBrowser/#/R-HSA-5210943 pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol) TAS Homo sapiens 29108 R-HSA-5210944 https://reactome.org/PathwayBrowser/#/R-HSA-5210944 Endocytosis of cya:lef:(pagA(197-794):ANTXR1 oligomer) (plasma membrane to endosome membrane) TAS Homo sapiens 29108 R-HSA-5210947 https://reactome.org/PathwayBrowser/#/R-HSA-5210947 pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol) TAS Homo sapiens 29108 R-HSA-5210959 https://reactome.org/PathwayBrowser/#/R-HSA-5210959 Endocytosis of cya:lef:(pagA(197-794):ANTXR2 oligomer) (plasma membrane to endosome membrane) TAS Homo sapiens 29108 R-HSA-5211224 https://reactome.org/PathwayBrowser/#/R-HSA-5211224 Anthrax cya catalyzes the conversion of ATP to cAMP TAS Homo sapiens 29108 R-HSA-5218813 https://reactome.org/PathwayBrowser/#/R-HSA-5218813 DAG and Ca+2 bind to PKC and tether it to membrane TAS Homo sapiens 29108 R-HSA-5218823 https://reactome.org/PathwayBrowser/#/R-HSA-5218823 PKC phosphorylates sphingosine kinase 1 TAS Homo sapiens 29108 R-HSA-5223304 https://reactome.org/PathwayBrowser/#/R-HSA-5223304 DAG and Ca+2 bind to PKC and tether it to membrane TAS Homo sapiens 29108 R-HSA-5229194 https://reactome.org/PathwayBrowser/#/R-HSA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation TAS Homo sapiens 29108 R-HSA-5260201 https://reactome.org/PathwayBrowser/#/R-HSA-5260201 p-AKT2 phosphorylates C2CD5 IEA Homo sapiens 29108 R-HSA-5263628 https://reactome.org/PathwayBrowser/#/R-HSA-5263628 CAV3:TRIM72:DYSF binds ANXAs IEA Homo sapiens 29108 R-HSA-5263633 https://reactome.org/PathwayBrowser/#/R-HSA-5263633 DYSF, CAV3 and TRIM72 bind TAS Homo sapiens 29108 R-HSA-5333671 https://reactome.org/PathwayBrowser/#/R-HSA-5333671 CLCAs self cleave TAS Homo sapiens 29108 R-HSA-5333678 https://reactome.org/PathwayBrowser/#/R-HSA-5333678 CPNEs bind PL TAS Homo sapiens 29108 R-HSA-5576895 https://reactome.org/PathwayBrowser/#/R-HSA-5576895 SCNAs:SNCBs transport Na+ from extracellular region to cytosol TAS Homo sapiens 29108 R-HSA-5577213 https://reactome.org/PathwayBrowser/#/R-HSA-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol TAS Homo sapiens 29108 R-HSA-5578883 https://reactome.org/PathwayBrowser/#/R-HSA-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) TAS Homo sapiens 29108 R-HSA-5591040 https://reactome.org/PathwayBrowser/#/R-HSA-5591040 Activated protein C cleaves Factor Va intermediate form for Factor Va TAS Homo sapiens 29108 R-HSA-5591052 https://reactome.org/PathwayBrowser/#/R-HSA-5591052 PROCR binds Protein C TAS Homo sapiens 29108 R-HSA-5591086 https://reactome.org/PathwayBrowser/#/R-HSA-5591086 SERPINA5 binds activated protein C TAS Homo sapiens 29108 R-HSA-5602080 https://reactome.org/PathwayBrowser/#/R-HSA-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. TAS Homo sapiens 29108 R-HSA-5602353 https://reactome.org/PathwayBrowser/#/R-HSA-5602353 Defective IRAK4 variants do not bind MyD88:MAL:BTK:activated TLR2/4 TAS Homo sapiens 29108 R-HSA-5602383 https://reactome.org/PathwayBrowser/#/R-HSA-5602383 Defective MyD88 does not oligomerize within the activated TLR2/4 complex TAS Homo sapiens 29108 R-HSA-5602606 https://reactome.org/PathwayBrowser/#/R-HSA-5602606 Defective MyD88 does not bind MAL(TIRAP):TLR2/4 TAS Homo sapiens 29108 R-HSA-5602672 https://reactome.org/PathwayBrowser/#/R-HSA-5602672 Defective IRAK4 does not bind MyD88 within the TLR2/4 complex TAS Homo sapiens 29108 R-HSA-5603467 https://reactome.org/PathwayBrowser/#/R-HSA-5603467 Activated protein C is released from PROCR TAS Homo sapiens 29108 R-HSA-5604929 https://reactome.org/PathwayBrowser/#/R-HSA-5604929 Activated protein C binds Protein S TAS Homo sapiens 29108 R-HSA-5606996 https://reactome.org/PathwayBrowser/#/R-HSA-5606996 Soluble PROCR binds activated protein C TAS Homo sapiens 29108 R-HSA-5607002 https://reactome.org/PathwayBrowser/#/R-HSA-5607002 Activated protein C cleaves factor VIIIa TAS Homo sapiens 29108 R-HSA-5607058 https://reactome.org/PathwayBrowser/#/R-HSA-5607058 Activated protein C:PROCR binds F2R TAS Homo sapiens 29108 R-HSA-5621615 https://reactome.org/PathwayBrowser/#/R-HSA-5621615 CD209 binds ICAM3 TAS Homo sapiens 29108 R-HSA-5625841 https://reactome.org/PathwayBrowser/#/R-HSA-5625841 Defective SLC24A1 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ TAS Homo sapiens 29108 R-HSA-5626270 https://reactome.org/PathwayBrowser/#/R-HSA-5626270 Defective SLC24A4 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ TAS Homo sapiens 29108 R-HSA-5626316 https://reactome.org/PathwayBrowser/#/R-HSA-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ TAS Homo sapiens 29108 R-HSA-5626356 https://reactome.org/PathwayBrowser/#/R-HSA-5626356 Defective SLC24A5 does not exchange cytosolic 4Na+ for Golgi luminal Ca2+, K+ TAS Homo sapiens 29108 R-HSA-5626507 https://reactome.org/PathwayBrowser/#/R-HSA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin TAS Homo sapiens 29108 R-HSA-5626549 https://reactome.org/PathwayBrowser/#/R-HSA-5626549 IQGAPs bind CALM1 TAS Homo sapiens 29108 R-HSA-5668629 https://reactome.org/PathwayBrowser/#/R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP TAS Homo sapiens 29108 R-HSA-5668978 https://reactome.org/PathwayBrowser/#/R-HSA-5668978 MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex IEA Homo sapiens 29108 R-HSA-5672304 https://reactome.org/PathwayBrowser/#/R-HSA-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 TAS Homo sapiens 29108 R-HSA-5672965 https://reactome.org/PathwayBrowser/#/R-HSA-5672965 RAS GEFs promote RAS nucleotide exchange TAS Homo sapiens 29108 R-HSA-5672969 https://reactome.org/PathwayBrowser/#/R-HSA-5672969 Phosphorylation of RAF TAS Homo sapiens 29108 R-HSA-5672972 https://reactome.org/PathwayBrowser/#/R-HSA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex TAS Homo sapiens 29108 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 29108 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 29108 R-HSA-5672980 https://reactome.org/PathwayBrowser/#/R-HSA-5672980 Dissociation of RAS:RAF complex TAS Homo sapiens 29108 R-HSA-5694018 https://reactome.org/PathwayBrowser/#/R-HSA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate TAS Homo sapiens 29108 R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 29108 R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 29108 R-HSA-622326 https://reactome.org/PathwayBrowser/#/R-HSA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors TAS Homo sapiens 29108 R-HSA-629595 https://reactome.org/PathwayBrowser/#/R-HSA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 29108 R-HSA-6798474 https://reactome.org/PathwayBrowser/#/R-HSA-6798474 S100A8:S100A9 binds Zn2+ TAS Homo sapiens 29108 R-HSA-6798489 https://reactome.org/PathwayBrowser/#/R-HSA-6798489 S100A7 or S100A7A binds Zn2+ TAS Homo sapiens 29108 R-HSA-6798528 https://reactome.org/PathwayBrowser/#/R-HSA-6798528 S100A8:S100A9 binds Mn2+ TAS Homo sapiens 29108 R-HSA-6802910 https://reactome.org/PathwayBrowser/#/R-HSA-6802910 Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants TAS Homo sapiens 29108 R-HSA-6802911 https://reactome.org/PathwayBrowser/#/R-HSA-6802911 High kinase activity BRAF complexes phosphorylate MAP2Ks TAS Homo sapiens 29108 R-HSA-6802912 https://reactome.org/PathwayBrowser/#/R-HSA-6802912 High kinase activity BRAF mutants bind MAP2Ks and MAPKs TAS Homo sapiens 29108 R-HSA-6802914 https://reactome.org/PathwayBrowser/#/R-HSA-6802914 RAS:GTP:moderate kinase activity p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 29108 R-HSA-6802916 https://reactome.org/PathwayBrowser/#/R-HSA-6802916 RAF is phosphorylated downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 29108 R-HSA-6802918 https://reactome.org/PathwayBrowser/#/R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants TAS Homo sapiens 29108 R-HSA-6802919 https://reactome.org/PathwayBrowser/#/R-HSA-6802919 RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 29108 R-HSA-6802921 https://reactome.org/PathwayBrowser/#/R-HSA-6802921 Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 29108 R-HSA-6802922 https://reactome.org/PathwayBrowser/#/R-HSA-6802922 Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS TAS Homo sapiens 29108 R-HSA-6802924 https://reactome.org/PathwayBrowser/#/R-HSA-6802924 RAF is phosphorylated downstream of oncogenic RAS TAS Homo sapiens 29108 R-HSA-6802925 https://reactome.org/PathwayBrowser/#/R-HSA-6802925 Mutant RAS:p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 29108 R-HSA-6802926 https://reactome.org/PathwayBrowser/#/R-HSA-6802926 Mutant RAS:p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 29108 R-HSA-6802927 https://reactome.org/PathwayBrowser/#/R-HSA-6802927 BRAF and RAF fusion mutant dimers are phosphorylated TAS Homo sapiens 29108 R-HSA-6802932 https://reactome.org/PathwayBrowser/#/R-HSA-6802932 Dissociation of BRAF/RAF fusion complex TAS Homo sapiens 29108 R-HSA-6802933 https://reactome.org/PathwayBrowser/#/R-HSA-6802933 p-BRAF and RAF fusion dimers phosphorylate MAP2Ks TAS Homo sapiens 29108 R-HSA-6802934 https://reactome.org/PathwayBrowser/#/R-HSA-6802934 p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs TAS Homo sapiens 29108 R-HSA-6802935 https://reactome.org/PathwayBrowser/#/R-HSA-6802935 MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers TAS Homo sapiens 29108 R-HSA-6802941 https://reactome.org/PathwayBrowser/#/R-HSA-6802941 RAF is paradoxically phosphorylated downstream of kinase-inactive RAF TAS Homo sapiens 29108 R-HSA-6802942 https://reactome.org/PathwayBrowser/#/R-HSA-6802942 RAS:GTP:p-RAF complexes paradoxically bind MAP2Ks and MAPKs TAS Homo sapiens 29108 R-HSA-6802943 https://reactome.org/PathwayBrowser/#/R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 29108 R-HSA-6803227 https://reactome.org/PathwayBrowser/#/R-HSA-6803227 Dissociation of high activity BRAF complexes TAS Homo sapiens 29108 R-HSA-6803230 https://reactome.org/PathwayBrowser/#/R-HSA-6803230 Dissociation of moderate activity BRAF complexes TAS Homo sapiens 29108 R-HSA-6803233 https://reactome.org/PathwayBrowser/#/R-HSA-6803233 Dissociation of oncogenic RAS:RAF complex TAS Homo sapiens 29108 R-HSA-6803234 https://reactome.org/PathwayBrowser/#/R-HSA-6803234 Dissociation of paradoxically activated RAS:BRAF complexes TAS Homo sapiens 29108 R-HSA-6804527 https://reactome.org/PathwayBrowser/#/R-HSA-6804527 INTL1 binds bacterial glycans TAS Homo sapiens 29108 R-HSA-6805943 https://reactome.org/PathwayBrowser/#/R-HSA-6805943 S100A1 binds TLR4:LY96 TAS Homo sapiens 29108 R-HSA-6810894 https://reactome.org/PathwayBrowser/#/R-HSA-6810894 Envoplakin, periplakin, involucrin, SPR binding mediated by TGM1 crosslinking TAS Homo sapiens 29108 R-HSA-71181 https://reactome.org/PathwayBrowser/#/R-HSA-71181 FAH cleaves 4FAA TAS Homo sapiens 29108 R-HSA-71401 https://reactome.org/PathwayBrowser/#/R-HSA-71401 OGDH dimer decarboxylates 2-OG TAS Homo sapiens 29108 R-HSA-71541 https://reactome.org/PathwayBrowser/#/R-HSA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP TAS Homo sapiens 29108 R-HSA-71588 https://reactome.org/PathwayBrowser/#/R-HSA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP TAS Homo sapiens 29108 R-HSA-74448 https://reactome.org/PathwayBrowser/#/R-HSA-74448 Calcium binds calmodulin IEA Homo sapiens 29108 R-HSA-74885 https://reactome.org/PathwayBrowser/#/R-HSA-74885 GUCYs converts GTP to cGMP TAS Homo sapiens 29108 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 29108 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 29108 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 29108 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 29108 R-HSA-74948 https://reactome.org/PathwayBrowser/#/R-HSA-74948 PP2A dephosphorylates p-RHO to RHO TAS Homo sapiens 29108 R-HSA-751040 https://reactome.org/PathwayBrowser/#/R-HSA-751040 PKC phosphorylates G alpha (z) IEA Homo sapiens 29108 R-HSA-8848658 https://reactome.org/PathwayBrowser/#/R-HSA-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins TAS Homo sapiens 29108 R-HSA-8850846 https://reactome.org/PathwayBrowser/#/R-HSA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates TAS Homo sapiens 29108 R-HSA-8850854 https://reactome.org/PathwayBrowser/#/R-HSA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates TAS Homo sapiens 29108 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 29108 R-HSA-8851110 https://reactome.org/PathwayBrowser/#/R-HSA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates TAS Homo sapiens 29108 R-HSA-8851129 https://reactome.org/PathwayBrowser/#/R-HSA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates TAS Homo sapiens 29108 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 29108 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 29108 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 29108 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 29108 R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 29108 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 29108 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 29108 R-HSA-8852509 https://reactome.org/PathwayBrowser/#/R-HSA-8852509 CL-LK binds carbohydrates on target cell surface TAS Homo sapiens 29108 R-HSA-8852716 https://reactome.org/PathwayBrowser/#/R-HSA-8852716 Thrombin, ELANE cleave C5 TAS Homo sapiens 29108 R-HSA-8857662 https://reactome.org/PathwayBrowser/#/R-HSA-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane TAS Homo sapiens 29108 R-HSA-8862771 https://reactome.org/PathwayBrowser/#/R-HSA-8862771 PLA2G2A binds bacterial phospholipids TAS Homo sapiens 29108 R-HSA-8863008 https://reactome.org/PathwayBrowser/#/R-HSA-8863008 Calpain activation TAS Homo sapiens 29108 R-HSA-8863009 https://reactome.org/PathwayBrowser/#/R-HSA-8863009 Influx of extracellular calcium TAS Homo sapiens 29108 R-HSA-8863012 https://reactome.org/PathwayBrowser/#/R-HSA-8863012 Calpain cleaves p35 to p25 IEA Homo sapiens 29108 R-HSA-8863895 https://reactome.org/PathwayBrowser/#/R-HSA-8863895 IKKB phosphorylates SNAP23 TAS Homo sapiens 29108 R-HSA-8868134 https://reactome.org/PathwayBrowser/#/R-HSA-8868134 CAST binds Ca2+ bound calpain TAS Homo sapiens 29108 R-HSA-8876497 https://reactome.org/PathwayBrowser/#/R-HSA-8876497 InlA binds CDH1 TAS Homo sapiens 29108 R-HSA-8876948 https://reactome.org/PathwayBrowser/#/R-HSA-8876948 SRC phosphorylates InlA-bound CDH1 and CTNNB1 TAS Homo sapiens 29108 R-HSA-8876993 https://reactome.org/PathwayBrowser/#/R-HSA-8876993 CBLL1 binds SRC-phosphorylated CDH1 complex TAS Homo sapiens 29108 R-HSA-8877003 https://reactome.org/PathwayBrowser/#/R-HSA-8877003 CBLL1 ubiqutinates the InlA-bound CDH1 complex TAS Homo sapiens 29108 R-HSA-8878787 https://reactome.org/PathwayBrowser/#/R-HSA-8878787 ALPI dimer hydrolyses phosphate monoesters TAS Homo sapiens 29108 R-HSA-888589 https://reactome.org/PathwayBrowser/#/R-HSA-888589 Release of GABA at the synapse TAS Homo sapiens 29108 R-HSA-8932599 https://reactome.org/PathwayBrowser/#/R-HSA-8932599 CALB1 binds 4xCa2+ TAS Homo sapiens 29108 R-HSA-8932633 https://reactome.org/PathwayBrowser/#/R-HSA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE TAS Homo sapiens 29108 R-HSA-8934446 https://reactome.org/PathwayBrowser/#/R-HSA-8934446 Activated PKC phosphorylates SHC1 TAS Homo sapiens 29108 R-HSA-8934819 https://reactome.org/PathwayBrowser/#/R-HSA-8934819 Cytoplasmic proteases cleave Profilaggrin producing Filaggrin TAS Homo sapiens 29108 R-HSA-8949145 https://reactome.org/PathwayBrowser/#/R-HSA-8949145 VDAC1,2,3 translocate calcium from the cytosol to the mitochondrial intermembrane space IEA Homo sapiens 29108 R-HSA-8949178 https://reactome.org/PathwayBrowser/#/R-HSA-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix TAS Homo sapiens 29108 R-HSA-8949687 https://reactome.org/PathwayBrowser/#/R-HSA-8949687 LETM1 exchanges protons (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Homo sapiens 29108 R-HSA-8949688 https://reactome.org/PathwayBrowser/#/R-HSA-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) TAS Homo sapiens 29108 R-HSA-8949703 https://reactome.org/PathwayBrowser/#/R-HSA-8949703 SLC8A3 (NCX3) exchanges sodium (cytosol) for calcium (mitochondrial intermembrane space) IEA Homo sapiens 29108 R-HSA-8982703 https://reactome.org/PathwayBrowser/#/R-HSA-8982703 PKC binds active G alpha (z) IEA Homo sapiens 29108 R-HSA-8982709 https://reactome.org/PathwayBrowser/#/R-HSA-8982709 G-alpha(z):PKC dissociates to give phosphorylated G alpha (z) IEA Homo sapiens 29108 R-HSA-8986937 https://reactome.org/PathwayBrowser/#/R-HSA-8986937 MECP2 is phosphorylated at T308 IEA Homo sapiens 29108 R-HSA-8986939 https://reactome.org/PathwayBrowser/#/R-HSA-8986939 MECP2 binds the NCoR/SMRT complex IEA Homo sapiens 29108 R-HSA-9005561 https://reactome.org/PathwayBrowser/#/R-HSA-9005561 Active PKA, CaMK IV do not phosphorylate MECP2 mutants R306C,(R306H) at T308 IEA Homo sapiens 29108 R-HSA-9006992 https://reactome.org/PathwayBrowser/#/R-HSA-9006992 MECP2 is phosphorylated at S423 IEA Homo sapiens 29108 R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 29108 R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 29108 R-HSA-9015379 https://reactome.org/PathwayBrowser/#/R-HSA-9015379 Factor IIa inhibitors (compounds) binds IIa TAS Homo sapiens 29108 R-HSA-9023163 https://reactome.org/PathwayBrowser/#/R-HSA-9023163 Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54) IEA Homo sapiens 29108 R-HSA-9023171 https://reactome.org/PathwayBrowser/#/R-HSA-9023171 Insulin secretory granule translocates across the cortical actin network IEA Homo sapiens 29108 R-HSA-9023173 https://reactome.org/PathwayBrowser/#/R-HSA-9023173 Insulin secretory granule docks at the plasma membrane IEA Homo sapiens 29108 R-HSA-9023178 https://reactome.org/PathwayBrowser/#/R-HSA-9023178 PCSK2 cleaves Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) IEA Homo sapiens 29108 R-HSA-9023196 https://reactome.org/PathwayBrowser/#/R-HSA-9023196 PCSK1 cleaves proinsulin to yield Insulin(25-56) and Insulin(57-110) IEA Homo sapiens 29108 R-HSA-9036046 https://reactome.org/PathwayBrowser/#/R-HSA-9036046 Defective IDS does not hydrolyse Heparan sulfate chain(5) TAS Homo sapiens 29108 R-HSA-9036065 https://reactome.org/PathwayBrowser/#/R-HSA-9036065 Defective ARSB does not hydrolyse DS TAS Homo sapiens 29108 R-HSA-936883 https://reactome.org/PathwayBrowser/#/R-HSA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen TAS Homo sapiens 29108 R-HSA-937022 https://reactome.org/PathwayBrowser/#/R-HSA-937022 IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP TAS Homo sapiens 29108 R-HSA-937059 https://reactome.org/PathwayBrowser/#/R-HSA-937059 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex TAS Homo sapiens 29108 R-HSA-937079 https://reactome.org/PathwayBrowser/#/R-HSA-937079 MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 TAS Homo sapiens 29108 R-HSA-9603302 https://reactome.org/PathwayBrowser/#/R-HSA-9603302 Factor IIa inhibitors (peptide) binds IIa TAS Homo sapiens 29108 R-HSA-9617326 https://reactome.org/PathwayBrowser/#/R-HSA-9617326 CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 IEA Homo sapiens 29108 R-HSA-9617535 https://reactome.org/PathwayBrowser/#/R-HSA-9617535 Activated calmodulin binds ADCY1,ADCY8 IEA Homo sapiens 29108 R-HSA-9617583 https://reactome.org/PathwayBrowser/#/R-HSA-9617583 CaMKII autophosphorylates IEA Homo sapiens 29108 R-HSA-9618750 https://reactome.org/PathwayBrowser/#/R-HSA-9618750 CaMKII phosphorylates AMPA receptor IEA Homo sapiens 29108 R-HSA-9618811 https://reactome.org/PathwayBrowser/#/R-HSA-9618811 Calcium binds calmodulin at the synapse IEA Homo sapiens 29108 R-HSA-9618834 https://reactome.org/PathwayBrowser/#/R-HSA-9618834 Activated calmodulin dissociates from CaMKII-gamma IEA Homo sapiens 29108 R-HSA-9618863 https://reactome.org/PathwayBrowser/#/R-HSA-9618863 CaMKK binds activated calmodulin in the nucleus IEA Homo sapiens 29108 R-HSA-9619125 https://reactome.org/PathwayBrowser/#/R-HSA-9619125 CaMKK phosphorylates CAMK4 IEA Homo sapiens 29108 R-HSA-9619214 https://reactome.org/PathwayBrowser/#/R-HSA-9619214 CaMKK binds activated calmodulin in the cytosol IEA Homo sapiens 29108 R-HSA-9619355 https://reactome.org/PathwayBrowser/#/R-HSA-9619355 CaMKK autophosphorylates in the cytosol TAS Homo sapiens 29108 R-HSA-9619367 https://reactome.org/PathwayBrowser/#/R-HSA-9619367 CaMKKs phosphorylate CAMK1 IEA Homo sapiens 29108 R-HSA-9619376 https://reactome.org/PathwayBrowser/#/R-HSA-9619376 CAMK1 binds calmodulin TAS Homo sapiens 29108 R-HSA-9619430 https://reactome.org/PathwayBrowser/#/R-HSA-9619430 PPM1E dephosphorylates CAMK4 IEA Homo sapiens 29108 R-HSA-9619449 https://reactome.org/PathwayBrowser/#/R-HSA-9619449 PPM1F dephosphorylates p-T286-CaMKII IEA Homo sapiens 29108 R-HSA-9619467 https://reactome.org/PathwayBrowser/#/R-HSA-9619467 PPM1F dephosphorylates CAMK1 IEA Homo sapiens 29108 R-HSA-9619478 https://reactome.org/PathwayBrowser/#/R-HSA-9619478 CAMKK2 phosphorylates AMPK IEA Homo sapiens 29108 R-HSA-9619783 https://reactome.org/PathwayBrowser/#/R-HSA-9619783 CAMK1 phosphorylates ARHGEF7-1 IEA Homo sapiens 29108 R-HSA-9626848 https://reactome.org/PathwayBrowser/#/R-HSA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex TAS Homo sapiens 29108 R-HSA-9639567 https://reactome.org/PathwayBrowser/#/R-HSA-9639567 NPAS4 gene transcription is repressed by KCNIP3 IEA Homo sapiens 29108 R-HSA-9640060 https://reactome.org/PathwayBrowser/#/R-HSA-9640060 KCNIP3 binds NPAS4 gene promoter IEA Homo sapiens 29108 R-HSA-9640063 https://reactome.org/PathwayBrowser/#/R-HSA-9640063 Ca2+ binds KCNIP3 IEA Homo sapiens 29108 R-HSA-9648983 https://reactome.org/PathwayBrowser/#/R-HSA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ TAS Homo sapiens 29108 R-HSA-9653249 https://reactome.org/PathwayBrowser/#/R-HSA-9653249 Cleavage of factor XII variant by activated thrombin TAS Homo sapiens 29108 R-HSA-9653585 https://reactome.org/PathwayBrowser/#/R-HSA-9653585 S-Farn-Me KRAS4B binds calmodulin TAS Homo sapiens 29108 R-HSA-9654521 https://reactome.org/PathwayBrowser/#/R-HSA-9654521 Calmodulin dissociates KRAS4B from the plasma membrane TAS Homo sapiens 29108 R-HSA-9654523 https://reactome.org/PathwayBrowser/#/R-HSA-9654523 ARL2:GTP bind PDE6D on KRAS4B TAS Homo sapiens 29108 R-HSA-9654525 https://reactome.org/PathwayBrowser/#/R-HSA-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ TAS Homo sapiens 29108 R-HSA-9654533 https://reactome.org/PathwayBrowser/#/R-HSA-9654533 KRAS4B recycles to the plasma membrane TAS Homo sapiens 29108 R-HSA-9656209 https://reactome.org/PathwayBrowser/#/R-HSA-9656209 Dissociation of RAS:RAF1 mutant complex TAS Homo sapiens 29108 R-HSA-9656211 https://reactome.org/PathwayBrowser/#/R-HSA-9656211 MAP2Ks and MAPKs bind to the activated mutant RAF1 complex TAS Homo sapiens 29108 R-HSA-9656212 https://reactome.org/PathwayBrowser/#/R-HSA-9656212 Phosphorylation of RAF1 mutants TAS Homo sapiens 29108 R-HSA-9656214 https://reactome.org/PathwayBrowser/#/R-HSA-9656214 MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants TAS Homo sapiens 29108 R-HSA-9656215 https://reactome.org/PathwayBrowser/#/R-HSA-9656215 RAF1 mutant complexes phosphorylate MAP2K dimer TAS Homo sapiens 29108 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 29108 R-HSA-9657603 https://reactome.org/PathwayBrowser/#/R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs TAS Homo sapiens 29108 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 29108 R-HSA-9657608 https://reactome.org/PathwayBrowser/#/R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK TAS Homo sapiens 29108 R-HSA-9659380 https://reactome.org/PathwayBrowser/#/R-HSA-9659380 Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell IEA Homo sapiens 29108 R-HSA-9659515 https://reactome.org/PathwayBrowser/#/R-HSA-9659515 CACNA1D:CACNA2D2:CACNB2 (Cav1.3 channel) transports Ca2+ into the cytosol of an inner hair cell IEA Homo sapiens 29108 R-HSA-9659568 https://reactome.org/PathwayBrowser/#/R-HSA-9659568 ANO1 transports cytosolic Cl- to extracellular region TAS Homo sapiens 29108 R-HSA-9662096 https://reactome.org/PathwayBrowser/#/R-HSA-9662096 Exocytosis of glutamate from cochlear inner hair cell IEA Homo sapiens 29108 R-HSA-9662114 https://reactome.org/PathwayBrowser/#/R-HSA-9662114 ATP2B2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region IEA Homo sapiens 29108 R-HSA-9663363 https://reactome.org/PathwayBrowser/#/R-HSA-9663363 Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell IEA Homo sapiens 29108 R-HSA-9663785 https://reactome.org/PathwayBrowser/#/R-HSA-9663785 CHRNA9:CHRNA10:AcCho transports Ca2+ from the extracellular region to the cytosol IEA Homo sapiens 29108 R-HSA-9664214 https://reactome.org/PathwayBrowser/#/R-HSA-9664214 ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region IEA Homo sapiens 29108 R-HSA-9666383 https://reactome.org/PathwayBrowser/#/R-HSA-9666383 F8 variant is not cleaved by thrombin TAS Homo sapiens 29108 R-HSA-9667809 https://reactome.org/PathwayBrowser/#/R-HSA-9667809 KCNMA1:KCNMB1 transports potassium ions from the cytosol to the extracellular region IEA Homo sapiens 29108 R-HSA-9668253 https://reactome.org/PathwayBrowser/#/R-HSA-9668253 Hyperactivation of factor X by FVIIIa:FIXa R384L TAS Homo sapiens 29108 R-HSA-9668365 https://reactome.org/PathwayBrowser/#/R-HSA-9668365 FVIIIa variant:FIXa does not convert FX to the active FXa TAS Homo sapiens 29108 R-HSA-9670874 https://reactome.org/PathwayBrowser/#/R-HSA-9670874 FIXa variant:FVIIIa does not convert FX to the active FXa TAS Homo sapiens 29108 R-HSA-9673223 https://reactome.org/PathwayBrowser/#/R-HSA-9673223 FIX(29-461) variant is not activated (factor XIa catalyst) TAS Homo sapiens 29108 R-HSA-9701055 https://reactome.org/PathwayBrowser/#/R-HSA-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol TAS Homo sapiens 29108 R-HSA-9701141 https://reactome.org/PathwayBrowser/#/R-HSA-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol TAS Homo sapiens 29108 R-HSA-9706720 https://reactome.org/PathwayBrowser/#/R-HSA-9706720 SARS-CoV-1 E transports Ca2+ TAS Homo sapiens 29108 R-HSA-9707186 https://reactome.org/PathwayBrowser/#/R-HSA-9707186 ALOX5 binds ALOX5 inhibitors TAS Homo sapiens 29108 R-HSA-9708859 https://reactome.org/PathwayBrowser/#/R-HSA-9708859 Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it TAS Homo sapiens 29108 R-HSA-9712190 https://reactome.org/PathwayBrowser/#/R-HSA-9712190 cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol IEA Homo sapiens 29108 R-HSA-9712195 https://reactome.org/PathwayBrowser/#/R-HSA-9712195 ANO2 dimer binds Ca2+ IEA Homo sapiens 29108 R-HSA-9712204 https://reactome.org/PathwayBrowser/#/R-HSA-9712204 ANO2:Ca2+ translocates Cl- from the cytosol to the extracellular region IEA Homo sapiens 29108 R-HSA-9717193 https://reactome.org/PathwayBrowser/#/R-HSA-9717193 GNB1,3:GNG13 binds PLCB2:Ca2+ IEA Homo sapiens 29108 R-HSA-9717205 https://reactome.org/PathwayBrowser/#/R-HSA-9717205 GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG IEA Homo sapiens 29108 R-HSA-9717215 https://reactome.org/PathwayBrowser/#/R-HSA-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol TAS Homo sapiens 29108 R-HSA-9717383 https://reactome.org/PathwayBrowser/#/R-HSA-9717383 TRPM4 transports Na+ from the extracellular region to the cytosol IEA Homo sapiens 29108 R-HSA-9717395 https://reactome.org/PathwayBrowser/#/R-HSA-9717395 TRPM5 transports Na+ from the extracellular region to the cytosol IEA Homo sapiens 29108 R-HSA-9727354 https://reactome.org/PathwayBrowser/#/R-HSA-9727354 Transit-amplifying cell of basal layer differentiates into keratinocyte of spinosum layer in interfollicular epidermis TAS Homo sapiens 29108 R-HSA-9727355 https://reactome.org/PathwayBrowser/#/R-HSA-9727355 Keratinocyte of granulosum layer differentiates into corneocyte of corneum layer in interfollicular epidermis TAS Homo sapiens 29108 R-HSA-9727359 https://reactome.org/PathwayBrowser/#/R-HSA-9727359 Keratinocyte of spinosum layer differentiates into keratinocyte of granulosum layer in interfollicular epidermis TAS Homo sapiens 29108 R-HSA-975311 https://reactome.org/PathwayBrowser/#/R-HSA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ TAS Homo sapiens 29108 R-HSA-9754616 https://reactome.org/PathwayBrowser/#/R-HSA-9754616 SARS-CoV-2 E pentamer transports Ca2+ IEA Homo sapiens 29108 R-HSA-9756136 https://reactome.org/PathwayBrowser/#/R-HSA-9756136 PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV IEA Homo sapiens 29108 R-HSA-9756150 https://reactome.org/PathwayBrowser/#/R-HSA-9756150 PON1,3 hydrolyse 4-OH-ATVL to 4-OH-ATV IEA Homo sapiens 29108 R-HSA-9756177 https://reactome.org/PathwayBrowser/#/R-HSA-9756177 PON1,3 hydrolyse ATVL to ATV TAS Homo sapiens 29108 R-HSA-976723 https://reactome.org/PathwayBrowser/#/R-HSA-976723 Serum amyloid P-component forms homopentamers TAS Homo sapiens 29108 R-HSA-976734 https://reactome.org/PathwayBrowser/#/R-HSA-976734 Amyloid fibrils have additional components TAS Homo sapiens 29108 R-HSA-976817 https://reactome.org/PathwayBrowser/#/R-HSA-976817 Formation of serum amyloid P decamer TAS Homo sapiens 29108 R-HSA-977224 https://reactome.org/PathwayBrowser/#/R-HSA-977224 Serum amyloid P binds DNA and chromatin TAS Homo sapiens 29108 R-HSA-9833671 https://reactome.org/PathwayBrowser/#/R-HSA-9833671 CDH11 forms heterotypic trans dimer with CDH24 IEA Homo sapiens 29108 R-HSA-9833672 https://reactome.org/PathwayBrowser/#/R-HSA-9833672 CDH11 forms heterotypic trans dimer with CDH8 IEA Homo sapiens 29108 R-HSA-9833674 https://reactome.org/PathwayBrowser/#/R-HSA-9833674 CDH11 forms homotypic trans dimer IEA Homo sapiens 29108 R-HSA-9840949 https://reactome.org/PathwayBrowser/#/R-HSA-9840949 ARSA removes sulfate from SM3 TAS Homo sapiens 29108 R-HSA-9853499 https://reactome.org/PathwayBrowser/#/R-HSA-9853499 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 29108 R-HSA-9853512 https://reactome.org/PathwayBrowser/#/R-HSA-9853512 DLST transfers succinyl to CoA TAS Homo sapiens 29108 R-MGA-5672766 https://reactome.org/PathwayBrowser/#/R-MGA-5672766 Turkey MYLK phosphorylates MRLCs of the non-muscle myosin II complex TAS Meleagris gallopavo 29108 R-MMU-111881 https://reactome.org/PathwayBrowser/#/R-MMU-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Mus musculus 29108 R-MMU-111883 https://reactome.org/PathwayBrowser/#/R-MMU-111883 Hydrolysis of phosphatidylcholine IEA Mus musculus 29108 R-MMU-111915 https://reactome.org/PathwayBrowser/#/R-MMU-111915 CAMK4 autophosphorylates IEA Mus musculus 29108 R-MMU-111930 https://reactome.org/PathwayBrowser/#/R-MMU-111930 Adenylate cyclase produces cAMP IEA Mus musculus 29108 R-MMU-111956 https://reactome.org/PathwayBrowser/#/R-MMU-111956 Calmodulin activates Cam-PDE 1 IEA Mus musculus 29108 R-MMU-111966 https://reactome.org/PathwayBrowser/#/R-MMU-111966 GRK2 binds CALM1:4Ca2+ IEA Mus musculus 29108 R-MMU-111970 https://reactome.org/PathwayBrowser/#/R-MMU-111970 PKC phosphorylates GRK2 IEA Mus musculus 29108 R-MMU-114553 https://reactome.org/PathwayBrowser/#/R-MMU-114553 Activation of conventional Protein Kinase C IEA Mus musculus 29108 R-MMU-114683 https://reactome.org/PathwayBrowser/#/R-MMU-114683 Phosphorylation of Platelet Sec-1 IEA Mus musculus 29108 R-MMU-114684 https://reactome.org/PathwayBrowser/#/R-MMU-114684 Phosphorylation of Syntaxin-4 IEA Mus musculus 29108 R-MMU-114697 https://reactome.org/PathwayBrowser/#/R-MMU-114697 Activated thrombin (factor IIa) cleaves PAR3,4, activating them IEA Mus musculus 29108 R-MMU-1168373 https://reactome.org/PathwayBrowser/#/R-MMU-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Mus musculus 29108 R-MMU-1168376 https://reactome.org/PathwayBrowser/#/R-MMU-1168376 STIM1 oligomerizes IEA Mus musculus 29108 R-MMU-1168635 https://reactome.org/PathwayBrowser/#/R-MMU-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Mus musculus 29108 R-MMU-1183128 https://reactome.org/PathwayBrowser/#/R-MMU-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Mus musculus 29108 R-MMU-139854 https://reactome.org/PathwayBrowser/#/R-MMU-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Mus musculus 29108 R-MMU-139855 https://reactome.org/PathwayBrowser/#/R-MMU-139855 P2X1-mediated entry of Ca++ from plasma IEA Mus musculus 29108 R-MMU-139941 https://reactome.org/PathwayBrowser/#/R-MMU-139941 Binding of IP3 to IP3 receptor IEA Mus musculus 29108 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 29108 R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 29108 R-MMU-140686 https://reactome.org/PathwayBrowser/#/R-MMU-140686 factor Va + factor Xa -> Va:Xa complex (prothrombinase) IEA Mus musculus 29108 R-MMU-140696 https://reactome.org/PathwayBrowser/#/R-MMU-140696 factor V -> factor Va + factor V activation peptide IEA Mus musculus 29108 R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 29108 R-MMU-140736 https://reactome.org/PathwayBrowser/#/R-MMU-140736 factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) IEA Mus musculus 29108 R-MMU-140748 https://reactome.org/PathwayBrowser/#/R-MMU-140748 tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex IEA Mus musculus 29108 R-MMU-140769 https://reactome.org/PathwayBrowser/#/R-MMU-140769 factor VII -> factor VIIa IEA Mus musculus 29108 R-MMU-140777 https://reactome.org/PathwayBrowser/#/R-MMU-140777 factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) IEA Mus musculus 29108 R-MMU-140783 https://reactome.org/PathwayBrowser/#/R-MMU-140783 tissue factor (TF) + factor VII (F7) -> TF:F7 complex IEA Mus musculus 29108 R-MMU-140791 https://reactome.org/PathwayBrowser/#/R-MMU-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Mus musculus 29108 R-MMU-140823 https://reactome.org/PathwayBrowser/#/R-MMU-140823 factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) IEA Mus musculus 29108 R-MMU-140825 https://reactome.org/PathwayBrowser/#/R-MMU-140825 TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa IEA Mus musculus 29108 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 29108 R-MMU-140847 https://reactome.org/PathwayBrowser/#/R-MMU-140847 factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain IEA Mus musculus 29108 R-MMU-140851 https://reactome.org/PathwayBrowser/#/R-MMU-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Mus musculus 29108 R-MMU-140870 https://reactome.org/PathwayBrowser/#/R-MMU-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Mus musculus 29108 R-MMU-140872 https://reactome.org/PathwayBrowser/#/R-MMU-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Mus musculus 29108 R-MMU-141026 https://reactome.org/PathwayBrowser/#/R-MMU-141026 Activated protein C cleaves factor Va to factor Vi intermediate form IEA Mus musculus 29108 R-MMU-141040 https://reactome.org/PathwayBrowser/#/R-MMU-141040 Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C IEA Mus musculus 29108 R-MMU-141046 https://reactome.org/PathwayBrowser/#/R-MMU-141046 activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin IEA Mus musculus 29108 R-MMU-1482604 https://reactome.org/PathwayBrowser/#/R-MMU-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Mus musculus 29108 R-MMU-1482612 https://reactome.org/PathwayBrowser/#/R-MMU-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 29108 R-MMU-1482656 https://reactome.org/PathwayBrowser/#/R-MMU-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Mus musculus 29108 R-MMU-1482679 https://reactome.org/PathwayBrowser/#/R-MMU-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Mus musculus 29108 R-MMU-1482685 https://reactome.org/PathwayBrowser/#/R-MMU-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 29108 R-MMU-1482759 https://reactome.org/PathwayBrowser/#/R-MMU-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Mus musculus 29108 R-MMU-1482771 https://reactome.org/PathwayBrowser/#/R-MMU-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Mus musculus 29108 R-MMU-1482776 https://reactome.org/PathwayBrowser/#/R-MMU-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Mus musculus 29108 R-MMU-1482816 https://reactome.org/PathwayBrowser/#/R-MMU-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Mus musculus 29108 R-MMU-1482825 https://reactome.org/PathwayBrowser/#/R-MMU-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Mus musculus 29108 R-MMU-1482828 https://reactome.org/PathwayBrowser/#/R-MMU-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Mus musculus 29108 R-MMU-1482856 https://reactome.org/PathwayBrowser/#/R-MMU-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Mus musculus 29108 R-MMU-1482862 https://reactome.org/PathwayBrowser/#/R-MMU-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Mus musculus 29108 R-MMU-1482868 https://reactome.org/PathwayBrowser/#/R-MMU-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Mus musculus 29108 R-MMU-1482884 https://reactome.org/PathwayBrowser/#/R-MMU-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Mus musculus 29108 R-MMU-1482887 https://reactome.org/PathwayBrowser/#/R-MMU-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Mus musculus 29108 R-MMU-1482897 https://reactome.org/PathwayBrowser/#/R-MMU-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Mus musculus 29108 R-MMU-1482900 https://reactome.org/PathwayBrowser/#/R-MMU-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Mus musculus 29108 R-MMU-1482907 https://reactome.org/PathwayBrowser/#/R-MMU-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Mus musculus 29108 R-MMU-1497784 https://reactome.org/PathwayBrowser/#/R-MMU-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Mus musculus 29108 R-MMU-1497796 https://reactome.org/PathwayBrowser/#/R-MMU-1497796 BH2 binding can lead to eNOS uncoupling IEA Mus musculus 29108 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 29108 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 29108 R-MMU-158164 https://reactome.org/PathwayBrowser/#/R-MMU-158164 factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) IEA Mus musculus 29108 R-MMU-158278 https://reactome.org/PathwayBrowser/#/R-MMU-158278 factor VIIIa + factor IXa -> factor VIIIa:factor IXa IEA Mus musculus 29108 R-MMU-158333 https://reactome.org/PathwayBrowser/#/R-MMU-158333 factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) IEA Mus musculus 29108 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 29108 R-MMU-1602368 https://reactome.org/PathwayBrowser/#/R-MMU-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Mus musculus 29108 R-MMU-1602374 https://reactome.org/PathwayBrowser/#/R-MMU-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Mus musculus 29108 R-MMU-1602377 https://reactome.org/PathwayBrowser/#/R-MMU-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Mus musculus 29108 R-MMU-1602398 https://reactome.org/PathwayBrowser/#/R-MMU-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Mus musculus 29108 R-MMU-1602417 https://reactome.org/PathwayBrowser/#/R-MMU-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Mus musculus 29108 R-MMU-1602446 https://reactome.org/PathwayBrowser/#/R-MMU-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Mus musculus 29108 R-MMU-1606789 https://reactome.org/PathwayBrowser/#/R-MMU-1606789 ARSB hydrolyses DS IEA Mus musculus 29108 R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 29108 R-MMU-1606839 https://reactome.org/PathwayBrowser/#/R-MMU-1606839 ARSC hydrolyzes steroid sulfates IEA Mus musculus 29108 R-MMU-1614362 https://reactome.org/PathwayBrowser/#/R-MMU-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Mus musculus 29108 R-MMU-166721 https://reactome.org/PathwayBrowser/#/R-MMU-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa IEA Mus musculus 29108 R-MMU-166726 https://reactome.org/PathwayBrowser/#/R-MMU-166726 Activation of MASPs IEA Mus musculus 29108 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus 29108 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus 29108 R-MMU-1675928 https://reactome.org/PathwayBrowser/#/R-MMU-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Mus musculus 29108 R-MMU-1675939 https://reactome.org/PathwayBrowser/#/R-MMU-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Mus musculus 29108 R-MMU-1675961 https://reactome.org/PathwayBrowser/#/R-MMU-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Mus musculus 29108 R-MMU-1676024 https://reactome.org/PathwayBrowser/#/R-MMU-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Mus musculus 29108 R-MMU-1676109 https://reactome.org/PathwayBrowser/#/R-MMU-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Mus musculus 29108 R-MMU-1676206 https://reactome.org/PathwayBrowser/#/R-MMU-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Mus musculus 29108 R-MMU-1678650 https://reactome.org/PathwayBrowser/#/R-MMU-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Mus musculus 29108 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus 29108 R-MMU-1793182 https://reactome.org/PathwayBrowser/#/R-MMU-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Mus musculus 29108 R-MMU-1793207 https://reactome.org/PathwayBrowser/#/R-MMU-1793207 ARSB hydrolyses C4S/C6S chains IEA Mus musculus 29108 R-MMU-181788 https://reactome.org/PathwayBrowser/#/R-MMU-181788 The signal peptide is excised from pre-pro-NGF TAS Mus musculus 29108 R-MMU-1855153 https://reactome.org/PathwayBrowser/#/R-MMU-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Mus musculus 29108 R-MMU-1855177 https://reactome.org/PathwayBrowser/#/R-MMU-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Mus musculus 29108 R-MMU-1855214 https://reactome.org/PathwayBrowser/#/R-MMU-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Mus musculus 29108 R-MMU-1855221 https://reactome.org/PathwayBrowser/#/R-MMU-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Mus musculus 29108 R-MMU-187020 https://reactome.org/PathwayBrowser/#/R-MMU-187020 Part of pro-beta-NGF is processed to mature beta-NGF IEA Mus musculus 29108 R-MMU-202110 https://reactome.org/PathwayBrowser/#/R-MMU-202110 eNOS:Caveolin-1 complex binds to CaM IEA Mus musculus 29108 R-MMU-202111 https://reactome.org/PathwayBrowser/#/R-MMU-202111 AKT1 phosphorylates eNOS IEA Mus musculus 29108 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 29108 R-MMU-202129 https://reactome.org/PathwayBrowser/#/R-MMU-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Mus musculus 29108 R-MMU-202137 https://reactome.org/PathwayBrowser/#/R-MMU-202137 AKT1 binds eNOS complex via HSP90 IEA Mus musculus 29108 R-MMU-202144 https://reactome.org/PathwayBrowser/#/R-MMU-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Mus musculus 29108 R-MMU-2025890 https://reactome.org/PathwayBrowser/#/R-MMU-2025890 Calcineurin binds NFATC1,2,3 IEA Mus musculus 29108 R-MMU-2025936 https://reactome.org/PathwayBrowser/#/R-MMU-2025936 Calcineurin Dephosphorylates Nfatc2 TAS Mus musculus 29108 R-MMU-2089943 https://reactome.org/PathwayBrowser/#/R-MMU-2089943 TRPC1 translocates calcium from the extracellular region to the cytosol IEA Mus musculus 29108 R-MMU-210420 https://reactome.org/PathwayBrowser/#/R-MMU-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Mus musculus 29108 R-MMU-210430 https://reactome.org/PathwayBrowser/#/R-MMU-210430 Release of L-Glutamate at the synapse IEA Mus musculus 29108 R-MMU-2160884 https://reactome.org/PathwayBrowser/#/R-MMU-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Mus musculus 29108 R-MMU-2160892 https://reactome.org/PathwayBrowser/#/R-MMU-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Mus musculus 29108 R-MMU-2161768 https://reactome.org/PathwayBrowser/#/R-MMU-2161768 EXA4 is converted to EXC4 by LTC4S IEA Mus musculus 29108 R-MMU-2161907 https://reactome.org/PathwayBrowser/#/R-MMU-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Mus musculus 29108 R-MMU-2161917 https://reactome.org/PathwayBrowser/#/R-MMU-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Mus musculus 29108 R-MMU-216806 https://reactome.org/PathwayBrowser/#/R-MMU-216806 Processing of Proinsulin to Insulin TAS Mus musculus 29108 R-MMU-216883 https://reactome.org/PathwayBrowser/#/R-MMU-216883 Exocytosis of Insulin TAS Mus musculus 29108 R-MMU-2248891 https://reactome.org/PathwayBrowser/#/R-MMU-2248891 M6PR transports activated ARSA to the lysosome IEA Mus musculus 29108 R-MMU-2424243 https://reactome.org/PathwayBrowser/#/R-MMU-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Mus musculus 29108 R-MMU-2514867 https://reactome.org/PathwayBrowser/#/R-MMU-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Mus musculus 29108 R-MMU-2534359 https://reactome.org/PathwayBrowser/#/R-MMU-2534359 CatSper Channel Mediated Calcium Transport IEA Mus musculus 29108 R-MMU-2581474 https://reactome.org/PathwayBrowser/#/R-MMU-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Mus musculus 29108 R-MMU-2586748 https://reactome.org/PathwayBrowser/#/R-MMU-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ IEA Mus musculus 29108 R-MMU-264976 https://reactome.org/PathwayBrowser/#/R-MMU-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Mus musculus 29108 R-MMU-265153 https://reactome.org/PathwayBrowser/#/R-MMU-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Mus musculus 29108 R-MMU-265296 https://reactome.org/PathwayBrowser/#/R-MMU-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Mus musculus 29108 R-MMU-265301 https://reactome.org/PathwayBrowser/#/R-MMU-265301 Corticotropin cleavage from POMC IEA Mus musculus 29108 R-MMU-265645 https://reactome.org/PathwayBrowser/#/R-MMU-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Mus musculus 29108 R-MMU-266050 https://reactome.org/PathwayBrowser/#/R-MMU-266050 LTA4 is converted to LTC4 by LTC4S IEA Mus musculus 29108 R-MMU-266051 https://reactome.org/PathwayBrowser/#/R-MMU-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Mus musculus 29108 R-MMU-2684901 https://reactome.org/PathwayBrowser/#/R-MMU-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Mus musculus 29108 R-MMU-2685505 https://reactome.org/PathwayBrowser/#/R-MMU-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Mus musculus 29108 R-MMU-2730664 https://reactome.org/PathwayBrowser/#/R-MMU-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Mus musculus 29108 R-MMU-2730849 https://reactome.org/PathwayBrowser/#/R-MMU-2730849 Calcineurin binds and dephosphorylates NFAT IEA Mus musculus 29108 R-MMU-2730865 https://reactome.org/PathwayBrowser/#/R-MMU-2730865 RasGRP interacts with DAG and Ca2+ TAS Mus musculus 29108 R-MMU-2730867 https://reactome.org/PathwayBrowser/#/R-MMU-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Mus musculus 29108 R-MMU-2730872 https://reactome.org/PathwayBrowser/#/R-MMU-2730872 Activation of Calcineurin IEA Mus musculus 29108 R-MMU-2744242 https://reactome.org/PathwayBrowser/#/R-MMU-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Mus musculus 29108 R-MMU-2744361 https://reactome.org/PathwayBrowser/#/R-MMU-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Mus musculus 29108 R-MMU-2855020 https://reactome.org/PathwayBrowser/#/R-MMU-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Mus musculus 29108 R-MMU-2855054 https://reactome.org/PathwayBrowser/#/R-MMU-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Mus musculus 29108 R-MMU-2855125 https://reactome.org/PathwayBrowser/#/R-MMU-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Mus musculus 29108 R-MMU-3229181 https://reactome.org/PathwayBrowser/#/R-MMU-3229181 CALM1:Ca2+ binds CNG channel IEA Mus musculus 29108 R-MMU-3295579 https://reactome.org/PathwayBrowser/#/R-MMU-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Mus musculus 29108 R-MMU-354066 https://reactome.org/PathwayBrowser/#/R-MMU-354066 Translocation of PTK2 to Focal complexes IEA Mus musculus 29108 R-MMU-354073 https://reactome.org/PathwayBrowser/#/R-MMU-354073 Autophosphorylation of PTK2 at Y397 IEA Mus musculus 29108 R-MMU-354087 https://reactome.org/PathwayBrowser/#/R-MMU-354087 Recruitment of GRB2 to p-PTK2 IEA Mus musculus 29108 R-MMU-354124 https://reactome.org/PathwayBrowser/#/R-MMU-354124 Phosphorylation of pPTK2 by SRC IEA Mus musculus 29108 R-MMU-354149 https://reactome.org/PathwayBrowser/#/R-MMU-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Mus musculus 29108 R-MMU-354165 https://reactome.org/PathwayBrowser/#/R-MMU-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Mus musculus 29108 R-MMU-354173 https://reactome.org/PathwayBrowser/#/R-MMU-354173 Activation of Rap1 by cytosolic GEFs IEA Mus musculus 29108 R-MMU-372448 https://reactome.org/PathwayBrowser/#/R-MMU-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Mus musculus 29108 R-MMU-372693 https://reactome.org/PathwayBrowser/#/R-MMU-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Mus musculus 29108 R-MMU-372697 https://reactome.org/PathwayBrowser/#/R-MMU-372697 Crk binding to p130cas IEA Mus musculus 29108 R-MMU-372705 https://reactome.org/PathwayBrowser/#/R-MMU-372705 Recruitment of BCAR1 to PTK2 complex IEA Mus musculus 29108 R-MMU-377640 https://reactome.org/PathwayBrowser/#/R-MMU-377640 Autophosphorylation of SRC IEA Mus musculus 29108 R-MMU-377641 https://reactome.org/PathwayBrowser/#/R-MMU-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Mus musculus 29108 R-MMU-377643 https://reactome.org/PathwayBrowser/#/R-MMU-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Mus musculus 29108 R-MMU-377644 https://reactome.org/PathwayBrowser/#/R-MMU-377644 Release of CSK from SRC IEA Mus musculus 29108 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 29108 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 29108 R-MMU-3827958 https://reactome.org/PathwayBrowser/#/R-MMU-3827958 E-cadherin degradation by MMP9, KLK7 IEA Mus musculus 29108 R-MMU-389463 https://reactome.org/PathwayBrowser/#/R-MMU-389463 Proteinase-activated receptors can bind thrombin IEA Mus musculus 29108 R-MMU-390593 https://reactome.org/PathwayBrowser/#/R-MMU-390593 ATP Hydrolysis By Myosin IEA Mus musculus 29108 R-MMU-390595 https://reactome.org/PathwayBrowser/#/R-MMU-390595 Calcium Binds Troponin-C IEA Mus musculus 29108 R-MMU-390597 https://reactome.org/PathwayBrowser/#/R-MMU-390597 Release Of ADP From Myosin IEA Mus musculus 29108 R-MMU-390598 https://reactome.org/PathwayBrowser/#/R-MMU-390598 Myosin Binds ATP IEA Mus musculus 29108 R-MMU-399712 https://reactome.org/PathwayBrowser/#/R-MMU-399712 Activation of Ca permeable AMPA receptors IEA Mus musculus 29108 R-MMU-416639 https://reactome.org/PathwayBrowser/#/R-MMU-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Mus musculus 29108 R-MMU-418309 https://reactome.org/PathwayBrowser/#/R-MMU-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Mus musculus 29108 R-MMU-418365 https://reactome.org/PathwayBrowser/#/R-MMU-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Mus musculus 29108 R-MMU-419001 https://reactome.org/PathwayBrowser/#/R-MMU-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Mus musculus 29108 R-MMU-420724 https://reactome.org/PathwayBrowser/#/R-MMU-420724 CASR binds Ca2+ IEA Mus musculus 29108 R-MMU-420739 https://reactome.org/PathwayBrowser/#/R-MMU-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Mus musculus 29108 R-MMU-421007 https://reactome.org/PathwayBrowser/#/R-MMU-421007 Endocytosis of Ca impermeable AMPA receptors IEA Mus musculus 29108 R-MMU-422021 https://reactome.org/PathwayBrowser/#/R-MMU-422021 PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin IEA Mus musculus 29108 R-MMU-4224014 https://reactome.org/PathwayBrowser/#/R-MMU-4224014 E-cadherin degradation by ADAM10, ADAM15 IEA Mus musculus 29108 R-MMU-425661 https://reactome.org/PathwayBrowser/#/R-MMU-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Mus musculus 29108 R-MMU-425678 https://reactome.org/PathwayBrowser/#/R-MMU-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Mus musculus 29108 R-MMU-425822 https://reactome.org/PathwayBrowser/#/R-MMU-425822 K+-independent Li+/Ca2+ exchanger transport IEA Mus musculus 29108 R-MMU-426223 https://reactome.org/PathwayBrowser/#/R-MMU-426223 Cation influx mediated by TRPC3/6/7 IEA Mus musculus 29108 R-MMU-427910 https://reactome.org/PathwayBrowser/#/R-MMU-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Mus musculus 29108 R-MMU-428262 https://reactome.org/PathwayBrowser/#/R-MMU-428262 ACER3 hydrolyzes phytoceramide IEA Mus musculus 29108 R-MMU-429016 https://reactome.org/PathwayBrowser/#/R-MMU-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Mus musculus 29108 R-MMU-429415 https://reactome.org/PathwayBrowser/#/R-MMU-429415 SYK binds to integrin alphaIIb beta3 IEA Mus musculus 29108 R-MMU-429441 https://reactome.org/PathwayBrowser/#/R-MMU-429441 SYK activation by SRC IEA Mus musculus 29108 R-MMU-429529 https://reactome.org/PathwayBrowser/#/R-MMU-429529 Thrombin binding to GP1b:IX:V IEA Mus musculus 29108 R-MMU-432164 https://reactome.org/PathwayBrowser/#/R-MMU-432164 Ca2+ influx into the post-synaptic cell IEA Mus musculus 29108 R-MMU-4332358 https://reactome.org/PathwayBrowser/#/R-MMU-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Mus musculus 29108 R-MMU-4332359 https://reactome.org/PathwayBrowser/#/R-MMU-4332359 Active calmodulin binds CAMK2 IEA Mus musculus 29108 R-MMU-4332363 https://reactome.org/PathwayBrowser/#/R-MMU-4332363 Autophosphorylation and activation of CAMK2 IEA Mus musculus 29108 R-MMU-438037 https://reactome.org/PathwayBrowser/#/R-MMU-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Mus musculus 29108 R-MMU-442749 https://reactome.org/PathwayBrowser/#/R-MMU-442749 CaMKK autophosphorylates in the nucleus IEA Mus musculus 29108 R-MMU-445699 https://reactome.org/PathwayBrowser/#/R-MMU-445699 ATP Hydrolysis By Myosin IEA Mus musculus 29108 R-MMU-445700 https://reactome.org/PathwayBrowser/#/R-MMU-445700 Myosin Binds ATP IEA Mus musculus 29108 R-MMU-445704 https://reactome.org/PathwayBrowser/#/R-MMU-445704 Calcium Binds Caldesmon IEA Mus musculus 29108 R-MMU-445705 https://reactome.org/PathwayBrowser/#/R-MMU-445705 Release Of ADP From Myosin IEA Mus musculus 29108 R-MMU-445797 https://reactome.org/PathwayBrowser/#/R-MMU-445797 MYLK (MLCK) Active Calmodulin Binding IEA Mus musculus 29108 R-MMU-445813 https://reactome.org/PathwayBrowser/#/R-MMU-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Mus musculus 29108 R-MMU-451311 https://reactome.org/PathwayBrowser/#/R-MMU-451311 Activation of Ca-permeable Kainate receptors IEA Mus musculus 29108 R-MMU-4551451 https://reactome.org/PathwayBrowser/#/R-MMU-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Mus musculus 29108 R-MMU-4551465 https://reactome.org/PathwayBrowser/#/R-MMU-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Mus musculus 29108 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 29108 R-MMU-5138432 https://reactome.org/PathwayBrowser/#/R-MMU-5138432 DVL2 is phosphorylated by PKC IEA Mus musculus 29108 R-MMU-5218813 https://reactome.org/PathwayBrowser/#/R-MMU-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Mus musculus 29108 R-MMU-5218823 https://reactome.org/PathwayBrowser/#/R-MMU-5218823 PKC phosphorylates sphingosine kinase 1 IEA Mus musculus 29108 R-MMU-5223304 https://reactome.org/PathwayBrowser/#/R-MMU-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Mus musculus 29108 R-MMU-5229194 https://reactome.org/PathwayBrowser/#/R-MMU-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Mus musculus 29108 R-MMU-5263624 https://reactome.org/PathwayBrowser/#/R-MMU-5263624 p-Akt2 phosphorylates C2cd5 TAS Mus musculus 29108 R-MMU-5333671 https://reactome.org/PathwayBrowser/#/R-MMU-5333671 CLCAs self cleave IEA Mus musculus 29108 R-MMU-5333678 https://reactome.org/PathwayBrowser/#/R-MMU-5333678 CPNEs bind PL IEA Mus musculus 29108 R-MMU-5577213 https://reactome.org/PathwayBrowser/#/R-MMU-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Mus musculus 29108 R-MMU-5578883 https://reactome.org/PathwayBrowser/#/R-MMU-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Mus musculus 29108 R-MMU-5591040 https://reactome.org/PathwayBrowser/#/R-MMU-5591040 Activated protein C cleaves Factor Va intermediate form for Factor Va IEA Mus musculus 29108 R-MMU-5591052 https://reactome.org/PathwayBrowser/#/R-MMU-5591052 PROCR binds Protein C IEA Mus musculus 29108 R-MMU-5591086 https://reactome.org/PathwayBrowser/#/R-MMU-5591086 SERPINA5 binds activated protein C IEA Mus musculus 29108 R-MMU-5602080 https://reactome.org/PathwayBrowser/#/R-MMU-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Mus musculus 29108 R-MMU-5603467 https://reactome.org/PathwayBrowser/#/R-MMU-5603467 Activated protein C is released from PROCR IEA Mus musculus 29108 R-MMU-5604929 https://reactome.org/PathwayBrowser/#/R-MMU-5604929 Activated protein C binds Protein S IEA Mus musculus 29108 R-MMU-5606996 https://reactome.org/PathwayBrowser/#/R-MMU-5606996 Soluble PROCR binds activated protein C IEA Mus musculus 29108 R-MMU-5607002 https://reactome.org/PathwayBrowser/#/R-MMU-5607002 Activated protein C cleaves factor VIIIa IEA Mus musculus 29108 R-MMU-5607058 https://reactome.org/PathwayBrowser/#/R-MMU-5607058 Activated protein C:PROCR binds F2R IEA Mus musculus 29108 R-MMU-5626316 https://reactome.org/PathwayBrowser/#/R-MMU-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Mus musculus 29108 R-MMU-5626507 https://reactome.org/PathwayBrowser/#/R-MMU-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Mus musculus 29108 R-MMU-5626549 https://reactome.org/PathwayBrowser/#/R-MMU-5626549 IQGAPs bind CALM1 IEA Mus musculus 29108 R-MMU-5668629 https://reactome.org/PathwayBrowser/#/R-MMU-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Mus musculus 29108 R-MMU-5672304 https://reactome.org/PathwayBrowser/#/R-MMU-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 IEA Mus musculus 29108 R-MMU-5672965 https://reactome.org/PathwayBrowser/#/R-MMU-5672965 RAS GEFs promote RAS nucleotide exchange IEA Mus musculus 29108 R-MMU-5672969 https://reactome.org/PathwayBrowser/#/R-MMU-5672969 Phosphorylation of RAF IEA Mus musculus 29108 R-MMU-5672972 https://reactome.org/PathwayBrowser/#/R-MMU-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Mus musculus 29108 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 29108 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 29108 R-MMU-5672980 https://reactome.org/PathwayBrowser/#/R-MMU-5672980 Dissociation of RAS:RAF complex IEA Mus musculus 29108 R-MMU-5694018 https://reactome.org/PathwayBrowser/#/R-MMU-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Mus musculus 29108 R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 29108 R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 29108 R-MMU-622326 https://reactome.org/PathwayBrowser/#/R-MMU-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Mus musculus 29108 R-MMU-629595 https://reactome.org/PathwayBrowser/#/R-MMU-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 29108 R-MMU-6798474 https://reactome.org/PathwayBrowser/#/R-MMU-6798474 S100A8:S100A9 binds Zn2+ IEA Mus musculus 29108 R-MMU-6798528 https://reactome.org/PathwayBrowser/#/R-MMU-6798528 S100A8:S100A9 binds Mn2+ IEA Mus musculus 29108 R-MMU-6804527 https://reactome.org/PathwayBrowser/#/R-MMU-6804527 INTL1 binds bacterial glycans IEA Mus musculus 29108 R-MMU-6805943 https://reactome.org/PathwayBrowser/#/R-MMU-6805943 S100A1 binds TLR4:LY96 IEA Mus musculus 29108 R-MMU-71181 https://reactome.org/PathwayBrowser/#/R-MMU-71181 FAH cleaves 4FAA IEA Mus musculus 29108 R-MMU-71401 https://reactome.org/PathwayBrowser/#/R-MMU-71401 OGDH dimer decarboxylates 2-OG IEA Mus musculus 29108 R-MMU-71541 https://reactome.org/PathwayBrowser/#/R-MMU-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Mus musculus 29108 R-MMU-71588 https://reactome.org/PathwayBrowser/#/R-MMU-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Mus musculus 29108 R-MMU-74885 https://reactome.org/PathwayBrowser/#/R-MMU-74885 GUCYs converts GTP to cGMP IEA Mus musculus 29108 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 29108 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 29108 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 29108 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 29108 R-MMU-74948 https://reactome.org/PathwayBrowser/#/R-MMU-74948 PP2A dephosphorylates p-RHO to RHO IEA Mus musculus 29108 R-MMU-8848658 https://reactome.org/PathwayBrowser/#/R-MMU-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Mus musculus 29108 R-MMU-8850846 https://reactome.org/PathwayBrowser/#/R-MMU-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Mus musculus 29108 R-MMU-8850854 https://reactome.org/PathwayBrowser/#/R-MMU-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Mus musculus 29108 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 29108 R-MMU-8851110 https://reactome.org/PathwayBrowser/#/R-MMU-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Mus musculus 29108 R-MMU-8851129 https://reactome.org/PathwayBrowser/#/R-MMU-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Mus musculus 29108 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 29108 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 29108 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 29108 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 29108 R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 29108 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 29108 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 29108 R-MMU-8852509 https://reactome.org/PathwayBrowser/#/R-MMU-8852509 CL-LK binds carbohydrates on target cell surface IEA Mus musculus 29108 R-MMU-8852716 https://reactome.org/PathwayBrowser/#/R-MMU-8852716 Thrombin, ELANE cleave C5 IEA Mus musculus 29108 R-MMU-8857662 https://reactome.org/PathwayBrowser/#/R-MMU-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Mus musculus 29108 R-MMU-8862771 https://reactome.org/PathwayBrowser/#/R-MMU-8862771 PLA2G2A binds bacterial phospholipids IEA Mus musculus 29108 R-MMU-8863416 https://reactome.org/PathwayBrowser/#/R-MMU-8863416 Calpain 1 or Calpain 2 cleaves Cdk5r1 (p35) TAS Mus musculus 29108 R-MMU-8878787 https://reactome.org/PathwayBrowser/#/R-MMU-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Mus musculus 29108 R-MMU-888589 https://reactome.org/PathwayBrowser/#/R-MMU-888589 Release of GABA at the synapse IEA Mus musculus 29108 R-MMU-8932633 https://reactome.org/PathwayBrowser/#/R-MMU-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Mus musculus 29108 R-MMU-8934446 https://reactome.org/PathwayBrowser/#/R-MMU-8934446 Activated PKC phosphorylates SHC1 IEA Mus musculus 29108 R-MMU-8949178 https://reactome.org/PathwayBrowser/#/R-MMU-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Mus musculus 29108 R-MMU-8949688 https://reactome.org/PathwayBrowser/#/R-MMU-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Mus musculus 29108 R-MMU-8951834 https://reactome.org/PathwayBrowser/#/R-MMU-8951834 Letm1 exchanges protons (mitochondrial intermembrane space) for calcium (mitochondrial matrix) TAS Mus musculus 29108 R-MMU-9005848 https://reactome.org/PathwayBrowser/#/R-MMU-9005848 Active Prkaca and CaMK IV phosphorylate Mecp2 at T308 TAS Mus musculus 29108 R-MMU-9005872 https://reactome.org/PathwayBrowser/#/R-MMU-9005872 Active Prkaca, CAMK IV does not phosphorylate Mecp2_e2 mutant R306C at T308 TAS Mus musculus 29108 R-MMU-9007015 https://reactome.org/PathwayBrowser/#/R-MMU-9007015 Mecp2 is phosphorylated at S421 TAS Mus musculus 29108 R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 29108 R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 29108 R-MMU-9015379 https://reactome.org/PathwayBrowser/#/R-MMU-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Mus musculus 29108 R-MMU-936883 https://reactome.org/PathwayBrowser/#/R-MMU-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Mus musculus 29108 R-MMU-9603302 https://reactome.org/PathwayBrowser/#/R-MMU-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Mus musculus 29108 R-MMU-9619355 https://reactome.org/PathwayBrowser/#/R-MMU-9619355 CaMKK autophosphorylates in the cytosol IEA Mus musculus 29108 R-MMU-9619376 https://reactome.org/PathwayBrowser/#/R-MMU-9619376 CAMK1 binds calmodulin IEA Mus musculus 29108 R-MMU-9626848 https://reactome.org/PathwayBrowser/#/R-MMU-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Mus musculus 29108 R-MMU-9640074 https://reactome.org/PathwayBrowser/#/R-MMU-9640074 Kcnip3 binds Npas4 gene promoter TAS Mus musculus 29108 R-MMU-9640094 https://reactome.org/PathwayBrowser/#/R-MMU-9640094 Ca2+ binds Kcnip3 TAS Mus musculus 29108 R-MMU-9648983 https://reactome.org/PathwayBrowser/#/R-MMU-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Mus musculus 29108 R-MMU-9653585 https://reactome.org/PathwayBrowser/#/R-MMU-9653585 S-Farn-Me KRAS4B binds calmodulin IEA Mus musculus 29108 R-MMU-9654521 https://reactome.org/PathwayBrowser/#/R-MMU-9654521 Calmodulin dissociates KRAS4B from the plasma membrane IEA Mus musculus 29108 R-MMU-9654523 https://reactome.org/PathwayBrowser/#/R-MMU-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Mus musculus 29108 R-MMU-9654525 https://reactome.org/PathwayBrowser/#/R-MMU-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ IEA Mus musculus 29108 R-MMU-9654533 https://reactome.org/PathwayBrowser/#/R-MMU-9654533 KRAS4B recycles to the plasma membrane IEA Mus musculus 29108 R-MMU-9657599 https://reactome.org/PathwayBrowser/#/R-MMU-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Mus musculus 29108 R-MMU-9657603 https://reactome.org/PathwayBrowser/#/R-MMU-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Mus musculus 29108 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 29108 R-MMU-9657608 https://reactome.org/PathwayBrowser/#/R-MMU-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Mus musculus 29108 R-MMU-9659489 https://reactome.org/PathwayBrowser/#/R-MMU-9659489 Cacna1d:Cacna2d2:Cacnb2 (Cav1.3 channel) transports calcium into the cytosol of an inner hair cell TAS Mus musculus 29108 R-MMU-9659536 https://reactome.org/PathwayBrowser/#/R-MMU-9659536 MET channel transports cations from the extracellular region into the cytosol of stereocilia of cochlear inner hair cell TAS Mus musculus 29108 R-MMU-9659568 https://reactome.org/PathwayBrowser/#/R-MMU-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Mus musculus 29108 R-MMU-9663360 https://reactome.org/PathwayBrowser/#/R-MMU-9663360 MET channel transports cations from the extracellular region into the cytosol of stereocilia of cochlear outer hair cell TAS Mus musculus 29108 R-MMU-9664156 https://reactome.org/PathwayBrowser/#/R-MMU-9664156 Exocytosis of glutamate from cochlear inner hair cell TAS Mus musculus 29108 R-MMU-9667762 https://reactome.org/PathwayBrowser/#/R-MMU-9667762 Kcnma1:Kcnmb1 transport potassium ions from the cytosol to the extracellular region TAS Mus musculus 29108 R-MMU-9668464 https://reactome.org/PathwayBrowser/#/R-MMU-9668464 Atp2b2 (PMCA2) transports Ca2+ from the cytosol to the extracellular region TAS Mus musculus 29108 R-MMU-9701055 https://reactome.org/PathwayBrowser/#/R-MMU-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Mus musculus 29108 R-MMU-9701141 https://reactome.org/PathwayBrowser/#/R-MMU-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Mus musculus 29108 R-MMU-9707186 https://reactome.org/PathwayBrowser/#/R-MMU-9707186 ALOX5 binds ALOX5 inhibitors IEA Mus musculus 29108 R-MMU-9708859 https://reactome.org/PathwayBrowser/#/R-MMU-9708859 Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it IEA Mus musculus 29108 R-MMU-9713672 https://reactome.org/PathwayBrowser/#/R-MMU-9713672 cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol TAS Mus musculus 29108 R-MMU-9714186 https://reactome.org/PathwayBrowser/#/R-MMU-9714186 Ano2 dimer:Ca2+ translocates Cl- from the cytosol to the extracellular region TAS Mus musculus 29108 R-MMU-9714790 https://reactome.org/PathwayBrowser/#/R-MMU-9714790 Ano1 dimer binds Ca2+ TAS Mus musculus 29108 R-MMU-9717215 https://reactome.org/PathwayBrowser/#/R-MMU-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Mus musculus 29108 R-MMU-9717432 https://reactome.org/PathwayBrowser/#/R-MMU-9717432 Trpm4 transports Na+ from the extracellular region to the cytosol TAS Mus musculus 29108 R-MMU-9717433 https://reactome.org/PathwayBrowser/#/R-MMU-9717433 Trpm5 transports Na+ from the extracellular region to the cytosol TAS Mus musculus 29108 R-MMU-975311 https://reactome.org/PathwayBrowser/#/R-MMU-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Mus musculus 29108 R-MMU-9756177 https://reactome.org/PathwayBrowser/#/R-MMU-9756177 PON1,3 hydrolyse ATVL to ATV IEA Mus musculus 29108 R-MMU-9840949 https://reactome.org/PathwayBrowser/#/R-MMU-9840949 ARSA removes sulfate from SM3 IEA Mus musculus 29108 R-MMU-9853499 https://reactome.org/PathwayBrowser/#/R-MMU-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 29108 R-MMU-9853512 https://reactome.org/PathwayBrowser/#/R-MMU-9853512 DLST transfers succinyl to CoA IEA Mus musculus 29108 R-NUL-209162 https://reactome.org/PathwayBrowser/#/R-NUL-209162 Murine ADAM10 cleaves Notch at the S2 site producing transmembrane spanning NEXT and ligand-bound NECD TAS Mus musculus 29108 R-NUL-2534209 https://reactome.org/PathwayBrowser/#/R-NUL-2534209 E-cadherin strand dimer degradation by PS1 TAS Homo sapiens 29108 R-NUL-804924 https://reactome.org/PathwayBrowser/#/R-NUL-804924 PKC (cow) phosphorylates G alpha z (rat) TAS Bos taurus 29108 R-NUL-8951809 https://reactome.org/PathwayBrowser/#/R-NUL-8951809 Slc8a3 (NCX3) exchanges sodium (cytosol) for calcium (mitochondrial intermembrane space) TAS Mus musculus 29108 R-NUL-8982704 https://reactome.org/PathwayBrowser/#/R-NUL-8982704 PKC (cow) binds G alpha z (rat) TAS Bos taurus 29108 R-NUL-8982712 https://reactome.org/PathwayBrowser/#/R-NUL-8982712 Gz(rat):PKC(cow) dissociates to give phosphorylated G alpha (z) TAS Bos taurus 29108 R-NUL-9023165 https://reactome.org/PathwayBrowser/#/R-NUL-9023165 Pcsk1 (rat) cleaves human proinsulin to yield Insulin(25-56) and Insulin(57-110) TAS Homo sapiens 29108 R-NUL-9023180 https://reactome.org/PathwayBrowser/#/R-NUL-9023180 Pcsk2 (rat) cleaves human Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) TAS Homo sapiens 29108 R-NUL-9617449 https://reactome.org/PathwayBrowser/#/R-NUL-9617449 Rasgrf1 promotes activation of HRAS TAS Rattus norvegicus 29108 R-NUL-9617570 https://reactome.org/PathwayBrowser/#/R-NUL-9617570 Activated calmodulin binds ADCY1 TAS Bos taurus 29108 R-NUL-9618897 https://reactome.org/PathwayBrowser/#/R-NUL-9618897 CAMKK2 binds activated calmodulin in the nucleus TAS Homo sapiens 29108 R-NUL-9618916 https://reactome.org/PathwayBrowser/#/R-NUL-9618916 Camkk1 binds activated calmodulin in the nucleus TAS Homo sapiens 29108 R-NUL-9619177 https://reactome.org/PathwayBrowser/#/R-NUL-9619177 Camkk2 phosphorylates CAMK4 TAS Homo sapiens 29108 R-NUL-9619239 https://reactome.org/PathwayBrowser/#/R-NUL-9619239 Camkk2 binds activated calmodulin in the cytosol TAS Homo sapiens 29108 R-NUL-9619243 https://reactome.org/PathwayBrowser/#/R-NUL-9619243 Camkk1 binds activated calmodulin in the cytosol TAS Homo sapiens 29108 R-NUL-9619396 https://reactome.org/PathwayBrowser/#/R-NUL-9619396 CAMKK1 phosphorylates CAMK1 TAS Homo sapiens 29108 R-NUL-9619413 https://reactome.org/PathwayBrowser/#/R-NUL-9619413 CAMKK2 phosphorylates Camk1 TAS Homo sapiens 29108 R-NUL-9619488 https://reactome.org/PathwayBrowser/#/R-NUL-9619488 Camkk2 phosphorylates AMPK TAS Rattus norvegicus 29108 R-NUL-9717194 https://reactome.org/PathwayBrowser/#/R-NUL-9717194 Gnb1:GNG2 binds PLCB2 TAS Bos taurus 29108 R-NUL-9717576 https://reactome.org/PathwayBrowser/#/R-NUL-9717576 Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG TAS Bos taurus 29108 R-PFA-111915 https://reactome.org/PathwayBrowser/#/R-PFA-111915 CAMK4 autophosphorylates IEA Plasmodium falciparum 29108 R-PFA-111956 https://reactome.org/PathwayBrowser/#/R-PFA-111956 Calmodulin activates Cam-PDE 1 IEA Plasmodium falciparum 29108 R-PFA-1497784 https://reactome.org/PathwayBrowser/#/R-PFA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Plasmodium falciparum 29108 R-PFA-1497796 https://reactome.org/PathwayBrowser/#/R-PFA-1497796 BH2 binding can lead to eNOS uncoupling IEA Plasmodium falciparum 29108 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 29108 R-PFA-1855153 https://reactome.org/PathwayBrowser/#/R-PFA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Plasmodium falciparum 29108 R-PFA-1855177 https://reactome.org/PathwayBrowser/#/R-PFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Plasmodium falciparum 29108 R-PFA-1855214 https://reactome.org/PathwayBrowser/#/R-PFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Plasmodium falciparum 29108 R-PFA-1855221 https://reactome.org/PathwayBrowser/#/R-PFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Plasmodium falciparum 29108 R-PFA-202111 https://reactome.org/PathwayBrowser/#/R-PFA-202111 AKT1 phosphorylates eNOS IEA Plasmodium falciparum 29108 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 29108 R-PFA-2730867 https://reactome.org/PathwayBrowser/#/R-PFA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Plasmodium falciparum 29108 R-PFA-2730872 https://reactome.org/PathwayBrowser/#/R-PFA-2730872 Activation of Calcineurin IEA Plasmodium falciparum 29108 R-PFA-418365 https://reactome.org/PathwayBrowser/#/R-PFA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Plasmodium falciparum 29108 R-PFA-427910 https://reactome.org/PathwayBrowser/#/R-PFA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Plasmodium falciparum 29108 R-PFA-4332358 https://reactome.org/PathwayBrowser/#/R-PFA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Plasmodium falciparum 29108 R-PFA-4332359 https://reactome.org/PathwayBrowser/#/R-PFA-4332359 Active calmodulin binds CAMK2 IEA Plasmodium falciparum 29108 R-PFA-4332363 https://reactome.org/PathwayBrowser/#/R-PFA-4332363 Autophosphorylation and activation of CAMK2 IEA Plasmodium falciparum 29108 R-PFA-4551465 https://reactome.org/PathwayBrowser/#/R-PFA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Plasmodium falciparum 29108 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 29108 R-PFA-5694018 https://reactome.org/PathwayBrowser/#/R-PFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Plasmodium falciparum 29108 R-PFA-71401 https://reactome.org/PathwayBrowser/#/R-PFA-71401 OGDH dimer decarboxylates 2-OG IEA Plasmodium falciparum 29108 R-PFA-8850846 https://reactome.org/PathwayBrowser/#/R-PFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 29108 R-PFA-8850854 https://reactome.org/PathwayBrowser/#/R-PFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 29108 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 29108 R-PFA-8851110 https://reactome.org/PathwayBrowser/#/R-PFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 29108 R-PFA-8851129 https://reactome.org/PathwayBrowser/#/R-PFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 29108 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 29108 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 29108 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 29108 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 29108 R-PFA-936883 https://reactome.org/PathwayBrowser/#/R-PFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Plasmodium falciparum 29108 R-PFA-9619376 https://reactome.org/PathwayBrowser/#/R-PFA-9619376 CAMK1 binds calmodulin IEA Plasmodium falciparum 29108 R-PFA-9853499 https://reactome.org/PathwayBrowser/#/R-PFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Plasmodium falciparum 29108 R-PFA-9853512 https://reactome.org/PathwayBrowser/#/R-PFA-9853512 DLST transfers succinyl to CoA IEA Plasmodium falciparum 29108 R-RNO-111881 https://reactome.org/PathwayBrowser/#/R-RNO-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Rattus norvegicus 29108 R-RNO-111883 https://reactome.org/PathwayBrowser/#/R-RNO-111883 Hydrolysis of phosphatidylcholine IEA Rattus norvegicus 29108 R-RNO-111915 https://reactome.org/PathwayBrowser/#/R-RNO-111915 CAMK4 autophosphorylates IEA Rattus norvegicus 29108 R-RNO-111930 https://reactome.org/PathwayBrowser/#/R-RNO-111930 Adenylate cyclase produces cAMP IEA Rattus norvegicus 29108 R-RNO-111956 https://reactome.org/PathwayBrowser/#/R-RNO-111956 Calmodulin activates Cam-PDE 1 IEA Rattus norvegicus 29108 R-RNO-111966 https://reactome.org/PathwayBrowser/#/R-RNO-111966 GRK2 binds CALM1:4Ca2+ IEA Rattus norvegicus 29108 R-RNO-111970 https://reactome.org/PathwayBrowser/#/R-RNO-111970 PKC phosphorylates GRK2 IEA Rattus norvegicus 29108 R-RNO-114553 https://reactome.org/PathwayBrowser/#/R-RNO-114553 Activation of conventional Protein Kinase C IEA Rattus norvegicus 29108 R-RNO-114683 https://reactome.org/PathwayBrowser/#/R-RNO-114683 Phosphorylation of Platelet Sec-1 IEA Rattus norvegicus 29108 R-RNO-114684 https://reactome.org/PathwayBrowser/#/R-RNO-114684 Phosphorylation of Syntaxin-4 IEA Rattus norvegicus 29108 R-RNO-114697 https://reactome.org/PathwayBrowser/#/R-RNO-114697 Activated thrombin (factor IIa) cleaves PAR3,4, activating them IEA Rattus norvegicus 29108 R-RNO-1168373 https://reactome.org/PathwayBrowser/#/R-RNO-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Rattus norvegicus 29108 R-RNO-1168376 https://reactome.org/PathwayBrowser/#/R-RNO-1168376 STIM1 oligomerizes IEA Rattus norvegicus 29108 R-RNO-1168635 https://reactome.org/PathwayBrowser/#/R-RNO-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Rattus norvegicus 29108 R-RNO-1183128 https://reactome.org/PathwayBrowser/#/R-RNO-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Rattus norvegicus 29108 R-RNO-139854 https://reactome.org/PathwayBrowser/#/R-RNO-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Rattus norvegicus 29108 R-RNO-139855 https://reactome.org/PathwayBrowser/#/R-RNO-139855 P2X1-mediated entry of Ca++ from plasma IEA Rattus norvegicus 29108 R-RNO-139941 https://reactome.org/PathwayBrowser/#/R-RNO-139941 Binding of IP3 to IP3 receptor IEA Rattus norvegicus 29108 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 29108 R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 29108 R-RNO-140736 https://reactome.org/PathwayBrowser/#/R-RNO-140736 factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) IEA Rattus norvegicus 29108 R-RNO-140748 https://reactome.org/PathwayBrowser/#/R-RNO-140748 tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex IEA Rattus norvegicus 29108 R-RNO-140769 https://reactome.org/PathwayBrowser/#/R-RNO-140769 factor VII -> factor VIIa IEA Rattus norvegicus 29108 R-RNO-140777 https://reactome.org/PathwayBrowser/#/R-RNO-140777 factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) IEA Rattus norvegicus 29108 R-RNO-140783 https://reactome.org/PathwayBrowser/#/R-RNO-140783 tissue factor (TF) + factor VII (F7) -> TF:F7 complex IEA Rattus norvegicus 29108 R-RNO-140791 https://reactome.org/PathwayBrowser/#/R-RNO-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Rattus norvegicus 29108 R-RNO-140823 https://reactome.org/PathwayBrowser/#/R-RNO-140823 factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) IEA Rattus norvegicus 29108 R-RNO-140825 https://reactome.org/PathwayBrowser/#/R-RNO-140825 TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa IEA Rattus norvegicus 29108 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 29108 R-RNO-140847 https://reactome.org/PathwayBrowser/#/R-RNO-140847 factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain IEA Rattus norvegicus 29108 R-RNO-140851 https://reactome.org/PathwayBrowser/#/R-RNO-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Rattus norvegicus 29108 R-RNO-140870 https://reactome.org/PathwayBrowser/#/R-RNO-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Rattus norvegicus 29108 R-RNO-140872 https://reactome.org/PathwayBrowser/#/R-RNO-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Rattus norvegicus 29108 R-RNO-141040 https://reactome.org/PathwayBrowser/#/R-RNO-141040 Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C IEA Rattus norvegicus 29108 R-RNO-141046 https://reactome.org/PathwayBrowser/#/R-RNO-141046 activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin IEA Rattus norvegicus 29108 R-RNO-1482604 https://reactome.org/PathwayBrowser/#/R-RNO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Rattus norvegicus 29108 R-RNO-1482612 https://reactome.org/PathwayBrowser/#/R-RNO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 29108 R-RNO-1482656 https://reactome.org/PathwayBrowser/#/R-RNO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Rattus norvegicus 29108 R-RNO-1482679 https://reactome.org/PathwayBrowser/#/R-RNO-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Rattus norvegicus 29108 R-RNO-1482685 https://reactome.org/PathwayBrowser/#/R-RNO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 29108 R-RNO-1482759 https://reactome.org/PathwayBrowser/#/R-RNO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Rattus norvegicus 29108 R-RNO-1482771 https://reactome.org/PathwayBrowser/#/R-RNO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Rattus norvegicus 29108 R-RNO-1482776 https://reactome.org/PathwayBrowser/#/R-RNO-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Rattus norvegicus 29108 R-RNO-1482816 https://reactome.org/PathwayBrowser/#/R-RNO-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Rattus norvegicus 29108 R-RNO-1482825 https://reactome.org/PathwayBrowser/#/R-RNO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Rattus norvegicus 29108 R-RNO-1482828 https://reactome.org/PathwayBrowser/#/R-RNO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Rattus norvegicus 29108 R-RNO-1482856 https://reactome.org/PathwayBrowser/#/R-RNO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Rattus norvegicus 29108 R-RNO-1482862 https://reactome.org/PathwayBrowser/#/R-RNO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Rattus norvegicus 29108 R-RNO-1482868 https://reactome.org/PathwayBrowser/#/R-RNO-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Rattus norvegicus 29108 R-RNO-1482884 https://reactome.org/PathwayBrowser/#/R-RNO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Rattus norvegicus 29108 R-RNO-1482887 https://reactome.org/PathwayBrowser/#/R-RNO-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Rattus norvegicus 29108 R-RNO-1482897 https://reactome.org/PathwayBrowser/#/R-RNO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Rattus norvegicus 29108 R-RNO-1482900 https://reactome.org/PathwayBrowser/#/R-RNO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Rattus norvegicus 29108 R-RNO-1482907 https://reactome.org/PathwayBrowser/#/R-RNO-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Rattus norvegicus 29108 R-RNO-1497784 https://reactome.org/PathwayBrowser/#/R-RNO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Rattus norvegicus 29108 R-RNO-1497796 https://reactome.org/PathwayBrowser/#/R-RNO-1497796 BH2 binding can lead to eNOS uncoupling IEA Rattus norvegicus 29108 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 29108 R-RNO-158164 https://reactome.org/PathwayBrowser/#/R-RNO-158164 factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) IEA Rattus norvegicus 29108 R-RNO-158278 https://reactome.org/PathwayBrowser/#/R-RNO-158278 factor VIIIa + factor IXa -> factor VIIIa:factor IXa IEA Rattus norvegicus 29108 R-RNO-158333 https://reactome.org/PathwayBrowser/#/R-RNO-158333 factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) IEA Rattus norvegicus 29108 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 29108 R-RNO-1602368 https://reactome.org/PathwayBrowser/#/R-RNO-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Rattus norvegicus 29108 R-RNO-1602374 https://reactome.org/PathwayBrowser/#/R-RNO-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Rattus norvegicus 29108 R-RNO-1602377 https://reactome.org/PathwayBrowser/#/R-RNO-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Rattus norvegicus 29108 R-RNO-1602398 https://reactome.org/PathwayBrowser/#/R-RNO-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Rattus norvegicus 29108 R-RNO-1602417 https://reactome.org/PathwayBrowser/#/R-RNO-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Rattus norvegicus 29108 R-RNO-1602446 https://reactome.org/PathwayBrowser/#/R-RNO-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Rattus norvegicus 29108 R-RNO-1606789 https://reactome.org/PathwayBrowser/#/R-RNO-1606789 ARSB hydrolyses DS IEA Rattus norvegicus 29108 R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 29108 R-RNO-1606839 https://reactome.org/PathwayBrowser/#/R-RNO-1606839 ARSC hydrolyzes steroid sulfates IEA Rattus norvegicus 29108 R-RNO-1614362 https://reactome.org/PathwayBrowser/#/R-RNO-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Rattus norvegicus 29108 R-RNO-166721 https://reactome.org/PathwayBrowser/#/R-RNO-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa IEA Rattus norvegicus 29108 R-RNO-166726 https://reactome.org/PathwayBrowser/#/R-RNO-166726 Activation of MASPs IEA Rattus norvegicus 29108 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus 29108 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus 29108 R-RNO-1675928 https://reactome.org/PathwayBrowser/#/R-RNO-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Rattus norvegicus 29108 R-RNO-1675939 https://reactome.org/PathwayBrowser/#/R-RNO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Rattus norvegicus 29108 R-RNO-1675961 https://reactome.org/PathwayBrowser/#/R-RNO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Rattus norvegicus 29108 R-RNO-1676024 https://reactome.org/PathwayBrowser/#/R-RNO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Rattus norvegicus 29108 R-RNO-1676109 https://reactome.org/PathwayBrowser/#/R-RNO-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Rattus norvegicus 29108 R-RNO-1676206 https://reactome.org/PathwayBrowser/#/R-RNO-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Rattus norvegicus 29108 R-RNO-1678650 https://reactome.org/PathwayBrowser/#/R-RNO-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Rattus norvegicus 29108 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus 29108 R-RNO-1793182 https://reactome.org/PathwayBrowser/#/R-RNO-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Rattus norvegicus 29108 R-RNO-1793207 https://reactome.org/PathwayBrowser/#/R-RNO-1793207 ARSB hydrolyses C4S/C6S chains IEA Rattus norvegicus 29108 R-RNO-182097 https://reactome.org/PathwayBrowser/#/R-RNO-182097 Calcium release from intracellular stores by IP3 receptor activation TAS Rattus norvegicus 29108 R-RNO-1855153 https://reactome.org/PathwayBrowser/#/R-RNO-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Rattus norvegicus 29108 R-RNO-1855177 https://reactome.org/PathwayBrowser/#/R-RNO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Rattus norvegicus 29108 R-RNO-1855214 https://reactome.org/PathwayBrowser/#/R-RNO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Rattus norvegicus 29108 R-RNO-1855221 https://reactome.org/PathwayBrowser/#/R-RNO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Rattus norvegicus 29108 R-RNO-187020 https://reactome.org/PathwayBrowser/#/R-RNO-187020 Part of pro-beta-NGF is processed to mature beta-NGF IEA Rattus norvegicus 29108 R-RNO-202110 https://reactome.org/PathwayBrowser/#/R-RNO-202110 eNOS:Caveolin-1 complex binds to CaM IEA Rattus norvegicus 29108 R-RNO-202111 https://reactome.org/PathwayBrowser/#/R-RNO-202111 AKT1 phosphorylates eNOS IEA Rattus norvegicus 29108 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 29108 R-RNO-202129 https://reactome.org/PathwayBrowser/#/R-RNO-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Rattus norvegicus 29108 R-RNO-202137 https://reactome.org/PathwayBrowser/#/R-RNO-202137 AKT1 binds eNOS complex via HSP90 IEA Rattus norvegicus 29108 R-RNO-202144 https://reactome.org/PathwayBrowser/#/R-RNO-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Rattus norvegicus 29108 R-RNO-2025890 https://reactome.org/PathwayBrowser/#/R-RNO-2025890 Calcineurin binds NFATC1,2,3 IEA Rattus norvegicus 29108 R-RNO-2089943 https://reactome.org/PathwayBrowser/#/R-RNO-2089943 TRPC1 translocates calcium from the extracellular region to the cytosol IEA Rattus norvegicus 29108 R-RNO-210420 https://reactome.org/PathwayBrowser/#/R-RNO-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Rattus norvegicus 29108 R-RNO-210430 https://reactome.org/PathwayBrowser/#/R-RNO-210430 Release of L-Glutamate at the synapse IEA Rattus norvegicus 29108 R-RNO-2160884 https://reactome.org/PathwayBrowser/#/R-RNO-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Rattus norvegicus 29108 R-RNO-2160892 https://reactome.org/PathwayBrowser/#/R-RNO-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Rattus norvegicus 29108 R-RNO-2161768 https://reactome.org/PathwayBrowser/#/R-RNO-2161768 EXA4 is converted to EXC4 by LTC4S IEA Rattus norvegicus 29108 R-RNO-2161907 https://reactome.org/PathwayBrowser/#/R-RNO-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Rattus norvegicus 29108 R-RNO-2161917 https://reactome.org/PathwayBrowser/#/R-RNO-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Rattus norvegicus 29108 R-RNO-2248891 https://reactome.org/PathwayBrowser/#/R-RNO-2248891 M6PR transports activated ARSA to the lysosome IEA Rattus norvegicus 29108 R-RNO-2424243 https://reactome.org/PathwayBrowser/#/R-RNO-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Rattus norvegicus 29108 R-RNO-2514867 https://reactome.org/PathwayBrowser/#/R-RNO-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Rattus norvegicus 29108 R-RNO-2534359 https://reactome.org/PathwayBrowser/#/R-RNO-2534359 CatSper Channel Mediated Calcium Transport IEA Rattus norvegicus 29108 R-RNO-2581474 https://reactome.org/PathwayBrowser/#/R-RNO-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Rattus norvegicus 29108 R-RNO-2586748 https://reactome.org/PathwayBrowser/#/R-RNO-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ IEA Rattus norvegicus 29108 R-RNO-264976 https://reactome.org/PathwayBrowser/#/R-RNO-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Rattus norvegicus 29108 R-RNO-265153 https://reactome.org/PathwayBrowser/#/R-RNO-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Rattus norvegicus 29108 R-RNO-265296 https://reactome.org/PathwayBrowser/#/R-RNO-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Rattus norvegicus 29108 R-RNO-265301 https://reactome.org/PathwayBrowser/#/R-RNO-265301 Corticotropin cleavage from POMC IEA Rattus norvegicus 29108 R-RNO-265645 https://reactome.org/PathwayBrowser/#/R-RNO-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Rattus norvegicus 29108 R-RNO-266050 https://reactome.org/PathwayBrowser/#/R-RNO-266050 LTA4 is converted to LTC4 by LTC4S IEA Rattus norvegicus 29108 R-RNO-266051 https://reactome.org/PathwayBrowser/#/R-RNO-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Rattus norvegicus 29108 R-RNO-2684901 https://reactome.org/PathwayBrowser/#/R-RNO-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Rattus norvegicus 29108 R-RNO-2685505 https://reactome.org/PathwayBrowser/#/R-RNO-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Rattus norvegicus 29108 R-RNO-2730664 https://reactome.org/PathwayBrowser/#/R-RNO-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Rattus norvegicus 29108 R-RNO-2730849 https://reactome.org/PathwayBrowser/#/R-RNO-2730849 Calcineurin binds and dephosphorylates NFAT IEA Rattus norvegicus 29108 R-RNO-2730867 https://reactome.org/PathwayBrowser/#/R-RNO-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Rattus norvegicus 29108 R-RNO-2730872 https://reactome.org/PathwayBrowser/#/R-RNO-2730872 Activation of Calcineurin IEA Rattus norvegicus 29108 R-RNO-2744242 https://reactome.org/PathwayBrowser/#/R-RNO-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Rattus norvegicus 29108 R-RNO-2744361 https://reactome.org/PathwayBrowser/#/R-RNO-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Rattus norvegicus 29108 R-RNO-2855020 https://reactome.org/PathwayBrowser/#/R-RNO-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Rattus norvegicus 29108 R-RNO-2855054 https://reactome.org/PathwayBrowser/#/R-RNO-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Rattus norvegicus 29108 R-RNO-2855125 https://reactome.org/PathwayBrowser/#/R-RNO-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Rattus norvegicus 29108 R-RNO-3229181 https://reactome.org/PathwayBrowser/#/R-RNO-3229181 CALM1:Ca2+ binds CNG channel IEA Rattus norvegicus 29108 R-RNO-3295579 https://reactome.org/PathwayBrowser/#/R-RNO-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Rattus norvegicus 29108 R-RNO-354066 https://reactome.org/PathwayBrowser/#/R-RNO-354066 Translocation of PTK2 to Focal complexes IEA Rattus norvegicus 29108 R-RNO-354073 https://reactome.org/PathwayBrowser/#/R-RNO-354073 Autophosphorylation of PTK2 at Y397 IEA Rattus norvegicus 29108 R-RNO-354087 https://reactome.org/PathwayBrowser/#/R-RNO-354087 Recruitment of GRB2 to p-PTK2 IEA Rattus norvegicus 29108 R-RNO-354124 https://reactome.org/PathwayBrowser/#/R-RNO-354124 Phosphorylation of pPTK2 by SRC IEA Rattus norvegicus 29108 R-RNO-354149 https://reactome.org/PathwayBrowser/#/R-RNO-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Rattus norvegicus 29108 R-RNO-354165 https://reactome.org/PathwayBrowser/#/R-RNO-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Rattus norvegicus 29108 R-RNO-354173 https://reactome.org/PathwayBrowser/#/R-RNO-354173 Activation of Rap1 by cytosolic GEFs IEA Rattus norvegicus 29108 R-RNO-372448 https://reactome.org/PathwayBrowser/#/R-RNO-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Rattus norvegicus 29108 R-RNO-372693 https://reactome.org/PathwayBrowser/#/R-RNO-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Rattus norvegicus 29108 R-RNO-372697 https://reactome.org/PathwayBrowser/#/R-RNO-372697 Crk binding to p130cas IEA Rattus norvegicus 29108 R-RNO-372705 https://reactome.org/PathwayBrowser/#/R-RNO-372705 Recruitment of BCAR1 to PTK2 complex IEA Rattus norvegicus 29108 R-RNO-377640 https://reactome.org/PathwayBrowser/#/R-RNO-377640 Autophosphorylation of SRC IEA Rattus norvegicus 29108 R-RNO-377641 https://reactome.org/PathwayBrowser/#/R-RNO-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Rattus norvegicus 29108 R-RNO-377643 https://reactome.org/PathwayBrowser/#/R-RNO-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Rattus norvegicus 29108 R-RNO-377644 https://reactome.org/PathwayBrowser/#/R-RNO-377644 Release of CSK from SRC IEA Rattus norvegicus 29108 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 29108 R-RNO-379832 https://reactome.org/PathwayBrowser/#/R-RNO-379832 CaMKIV phosphorylates Creb1 TAS Rattus norvegicus 29108 R-RNO-379960 https://reactome.org/PathwayBrowser/#/R-RNO-379960 Calmodulin binds CaMK IV TAS Rattus norvegicus 29108 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 29108 R-RNO-381446 https://reactome.org/PathwayBrowser/#/R-RNO-381446 Thrombin proteolyzes IGF:IGFBP3:ALS IEA Rattus norvegicus 29108 R-RNO-3827958 https://reactome.org/PathwayBrowser/#/R-RNO-3827958 E-cadherin degradation by MMP9, KLK7 IEA Rattus norvegicus 29108 R-RNO-389463 https://reactome.org/PathwayBrowser/#/R-RNO-389463 Proteinase-activated receptors can bind thrombin IEA Rattus norvegicus 29108 R-RNO-390593 https://reactome.org/PathwayBrowser/#/R-RNO-390593 ATP Hydrolysis By Myosin IEA Rattus norvegicus 29108 R-RNO-390595 https://reactome.org/PathwayBrowser/#/R-RNO-390595 Calcium Binds Troponin-C IEA Rattus norvegicus 29108 R-RNO-390597 https://reactome.org/PathwayBrowser/#/R-RNO-390597 Release Of ADP From Myosin IEA Rattus norvegicus 29108 R-RNO-390598 https://reactome.org/PathwayBrowser/#/R-RNO-390598 Myosin Binds ATP IEA Rattus norvegicus 29108 R-RNO-399712 https://reactome.org/PathwayBrowser/#/R-RNO-399712 Activation of Ca permeable AMPA receptors IEA Rattus norvegicus 29108 R-RNO-416639 https://reactome.org/PathwayBrowser/#/R-RNO-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Rattus norvegicus 29108 R-RNO-418309 https://reactome.org/PathwayBrowser/#/R-RNO-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Rattus norvegicus 29108 R-RNO-418365 https://reactome.org/PathwayBrowser/#/R-RNO-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Rattus norvegicus 29108 R-RNO-419001 https://reactome.org/PathwayBrowser/#/R-RNO-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Rattus norvegicus 29108 R-RNO-420724 https://reactome.org/PathwayBrowser/#/R-RNO-420724 CASR binds Ca2+ IEA Rattus norvegicus 29108 R-RNO-420739 https://reactome.org/PathwayBrowser/#/R-RNO-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Rattus norvegicus 29108 R-RNO-421007 https://reactome.org/PathwayBrowser/#/R-RNO-421007 Endocytosis of Ca impermeable AMPA receptors IEA Rattus norvegicus 29108 R-RNO-422021 https://reactome.org/PathwayBrowser/#/R-RNO-422021 PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin IEA Rattus norvegicus 29108 R-RNO-4224014 https://reactome.org/PathwayBrowser/#/R-RNO-4224014 E-cadherin degradation by ADAM10, ADAM15 IEA Rattus norvegicus 29108 R-RNO-425661 https://reactome.org/PathwayBrowser/#/R-RNO-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Rattus norvegicus 29108 R-RNO-425678 https://reactome.org/PathwayBrowser/#/R-RNO-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Rattus norvegicus 29108 R-RNO-425822 https://reactome.org/PathwayBrowser/#/R-RNO-425822 K+-independent Li+/Ca2+ exchanger transport IEA Rattus norvegicus 29108 R-RNO-426223 https://reactome.org/PathwayBrowser/#/R-RNO-426223 Cation influx mediated by TRPC3/6/7 IEA Rattus norvegicus 29108 R-RNO-427910 https://reactome.org/PathwayBrowser/#/R-RNO-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Rattus norvegicus 29108 R-RNO-428262 https://reactome.org/PathwayBrowser/#/R-RNO-428262 ACER3 hydrolyzes phytoceramide IEA Rattus norvegicus 29108 R-RNO-429016 https://reactome.org/PathwayBrowser/#/R-RNO-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Rattus norvegicus 29108 R-RNO-429415 https://reactome.org/PathwayBrowser/#/R-RNO-429415 SYK binds to integrin alphaIIb beta3 IEA Rattus norvegicus 29108 R-RNO-429441 https://reactome.org/PathwayBrowser/#/R-RNO-429441 SYK activation by SRC IEA Rattus norvegicus 29108 R-RNO-429529 https://reactome.org/PathwayBrowser/#/R-RNO-429529 Thrombin binding to GP1b:IX:V IEA Rattus norvegicus 29108 R-RNO-432164 https://reactome.org/PathwayBrowser/#/R-RNO-432164 Ca2+ influx into the post-synaptic cell IEA Rattus norvegicus 29108 R-RNO-4332358 https://reactome.org/PathwayBrowser/#/R-RNO-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Rattus norvegicus 29108 R-RNO-4332359 https://reactome.org/PathwayBrowser/#/R-RNO-4332359 Active calmodulin binds CAMK2 IEA Rattus norvegicus 29108 R-RNO-4332363 https://reactome.org/PathwayBrowser/#/R-RNO-4332363 Autophosphorylation and activation of CAMK2 IEA Rattus norvegicus 29108 R-RNO-438037 https://reactome.org/PathwayBrowser/#/R-RNO-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Rattus norvegicus 29108 R-RNO-442749 https://reactome.org/PathwayBrowser/#/R-RNO-442749 CaMKK autophosphorylates in the nucleus IEA Rattus norvegicus 29108 R-RNO-445700 https://reactome.org/PathwayBrowser/#/R-RNO-445700 Myosin Binds ATP IEA Rattus norvegicus 29108 R-RNO-445704 https://reactome.org/PathwayBrowser/#/R-RNO-445704 Calcium Binds Caldesmon IEA Rattus norvegicus 29108 R-RNO-445705 https://reactome.org/PathwayBrowser/#/R-RNO-445705 Release Of ADP From Myosin IEA Rattus norvegicus 29108 R-RNO-445797 https://reactome.org/PathwayBrowser/#/R-RNO-445797 MYLK (MLCK) Active Calmodulin Binding IEA Rattus norvegicus 29108 R-RNO-445813 https://reactome.org/PathwayBrowser/#/R-RNO-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Rattus norvegicus 29108 R-RNO-451311 https://reactome.org/PathwayBrowser/#/R-RNO-451311 Activation of Ca-permeable Kainate receptors IEA Rattus norvegicus 29108 R-RNO-4551451 https://reactome.org/PathwayBrowser/#/R-RNO-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Rattus norvegicus 29108 R-RNO-4551465 https://reactome.org/PathwayBrowser/#/R-RNO-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Rattus norvegicus 29108 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 29108 R-RNO-5138432 https://reactome.org/PathwayBrowser/#/R-RNO-5138432 DVL2 is phosphorylated by PKC IEA Rattus norvegicus 29108 R-RNO-5218813 https://reactome.org/PathwayBrowser/#/R-RNO-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Rattus norvegicus 29108 R-RNO-5218823 https://reactome.org/PathwayBrowser/#/R-RNO-5218823 PKC phosphorylates sphingosine kinase 1 IEA Rattus norvegicus 29108 R-RNO-5223304 https://reactome.org/PathwayBrowser/#/R-RNO-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Rattus norvegicus 29108 R-RNO-5229194 https://reactome.org/PathwayBrowser/#/R-RNO-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Rattus norvegicus 29108 R-RNO-5333671 https://reactome.org/PathwayBrowser/#/R-RNO-5333671 CLCAs self cleave IEA Rattus norvegicus 29108 R-RNO-5333678 https://reactome.org/PathwayBrowser/#/R-RNO-5333678 CPNEs bind PL IEA Rattus norvegicus 29108 R-RNO-5577213 https://reactome.org/PathwayBrowser/#/R-RNO-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Rattus norvegicus 29108 R-RNO-5578883 https://reactome.org/PathwayBrowser/#/R-RNO-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Rattus norvegicus 29108 R-RNO-5591052 https://reactome.org/PathwayBrowser/#/R-RNO-5591052 PROCR binds Protein C IEA Rattus norvegicus 29108 R-RNO-5591086 https://reactome.org/PathwayBrowser/#/R-RNO-5591086 SERPINA5 binds activated protein C IEA Rattus norvegicus 29108 R-RNO-5602080 https://reactome.org/PathwayBrowser/#/R-RNO-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Rattus norvegicus 29108 R-RNO-5603467 https://reactome.org/PathwayBrowser/#/R-RNO-5603467 Activated protein C is released from PROCR IEA Rattus norvegicus 29108 R-RNO-5604929 https://reactome.org/PathwayBrowser/#/R-RNO-5604929 Activated protein C binds Protein S IEA Rattus norvegicus 29108 R-RNO-5606996 https://reactome.org/PathwayBrowser/#/R-RNO-5606996 Soluble PROCR binds activated protein C IEA Rattus norvegicus 29108 R-RNO-5607002 https://reactome.org/PathwayBrowser/#/R-RNO-5607002 Activated protein C cleaves factor VIIIa IEA Rattus norvegicus 29108 R-RNO-5607058 https://reactome.org/PathwayBrowser/#/R-RNO-5607058 Activated protein C:PROCR binds F2R IEA Rattus norvegicus 29108 R-RNO-5626316 https://reactome.org/PathwayBrowser/#/R-RNO-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Rattus norvegicus 29108 R-RNO-5626507 https://reactome.org/PathwayBrowser/#/R-RNO-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Rattus norvegicus 29108 R-RNO-5626549 https://reactome.org/PathwayBrowser/#/R-RNO-5626549 IQGAPs bind CALM1 IEA Rattus norvegicus 29108 R-RNO-5668629 https://reactome.org/PathwayBrowser/#/R-RNO-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Rattus norvegicus 29108 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus 29108 R-RNO-5672969 https://reactome.org/PathwayBrowser/#/R-RNO-5672969 Phosphorylation of RAF IEA Rattus norvegicus 29108 R-RNO-5672972 https://reactome.org/PathwayBrowser/#/R-RNO-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Rattus norvegicus 29108 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 29108 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 29108 R-RNO-5672980 https://reactome.org/PathwayBrowser/#/R-RNO-5672980 Dissociation of RAS:RAF complex IEA Rattus norvegicus 29108 R-RNO-5694018 https://reactome.org/PathwayBrowser/#/R-RNO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Rattus norvegicus 29108 R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 29108 R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 29108 R-RNO-622326 https://reactome.org/PathwayBrowser/#/R-RNO-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Rattus norvegicus 29108 R-RNO-629595 https://reactome.org/PathwayBrowser/#/R-RNO-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 29108 R-RNO-6798474 https://reactome.org/PathwayBrowser/#/R-RNO-6798474 S100A8:S100A9 binds Zn2+ IEA Rattus norvegicus 29108 R-RNO-6798528 https://reactome.org/PathwayBrowser/#/R-RNO-6798528 S100A8:S100A9 binds Mn2+ IEA Rattus norvegicus 29108 R-RNO-6804527 https://reactome.org/PathwayBrowser/#/R-RNO-6804527 INTL1 binds bacterial glycans IEA Rattus norvegicus 29108 R-RNO-6805943 https://reactome.org/PathwayBrowser/#/R-RNO-6805943 S100A1 binds TLR4:LY96 IEA Rattus norvegicus 29108 R-RNO-71181 https://reactome.org/PathwayBrowser/#/R-RNO-71181 FAH cleaves 4FAA IEA Rattus norvegicus 29108 R-RNO-71401 https://reactome.org/PathwayBrowser/#/R-RNO-71401 OGDH dimer decarboxylates 2-OG IEA Rattus norvegicus 29108 R-RNO-71541 https://reactome.org/PathwayBrowser/#/R-RNO-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Rattus norvegicus 29108 R-RNO-71588 https://reactome.org/PathwayBrowser/#/R-RNO-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Rattus norvegicus 29108 R-RNO-74885 https://reactome.org/PathwayBrowser/#/R-RNO-74885 GUCYs converts GTP to cGMP IEA Rattus norvegicus 29108 R-RNO-74948 https://reactome.org/PathwayBrowser/#/R-RNO-74948 PP2A dephosphorylates p-RHO to RHO IEA Rattus norvegicus 29108 R-RNO-8848658 https://reactome.org/PathwayBrowser/#/R-RNO-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Rattus norvegicus 29108 R-RNO-8850846 https://reactome.org/PathwayBrowser/#/R-RNO-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 29108 R-RNO-8850854 https://reactome.org/PathwayBrowser/#/R-RNO-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 29108 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 29108 R-RNO-8851110 https://reactome.org/PathwayBrowser/#/R-RNO-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 29108 R-RNO-8851129 https://reactome.org/PathwayBrowser/#/R-RNO-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 29108 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 29108 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 29108 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 29108 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 29108 R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 29108 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 29108 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 29108 R-RNO-8852509 https://reactome.org/PathwayBrowser/#/R-RNO-8852509 CL-LK binds carbohydrates on target cell surface IEA Rattus norvegicus 29108 R-RNO-8852716 https://reactome.org/PathwayBrowser/#/R-RNO-8852716 Thrombin, ELANE cleave C5 IEA Rattus norvegicus 29108 R-RNO-8857662 https://reactome.org/PathwayBrowser/#/R-RNO-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Rattus norvegicus 29108 R-RNO-8862771 https://reactome.org/PathwayBrowser/#/R-RNO-8862771 PLA2G2A binds bacterial phospholipids IEA Rattus norvegicus 29108 R-RNO-8878787 https://reactome.org/PathwayBrowser/#/R-RNO-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Rattus norvegicus 29108 R-RNO-888589 https://reactome.org/PathwayBrowser/#/R-RNO-888589 Release of GABA at the synapse IEA Rattus norvegicus 29108 R-RNO-8932633 https://reactome.org/PathwayBrowser/#/R-RNO-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Rattus norvegicus 29108 R-RNO-8934446 https://reactome.org/PathwayBrowser/#/R-RNO-8934446 Activated PKC phosphorylates SHC1 IEA Rattus norvegicus 29108 R-RNO-8949178 https://reactome.org/PathwayBrowser/#/R-RNO-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Rattus norvegicus 29108 R-RNO-8949688 https://reactome.org/PathwayBrowser/#/R-RNO-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Rattus norvegicus 29108 R-RNO-8949737 https://reactome.org/PathwayBrowser/#/R-RNO-8949737 Vdac1 translocates calcium from the cytosol to the mitochondrial intermembrane space TAS Rattus norvegicus 29108 R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 29108 R-RNO-9015379 https://reactome.org/PathwayBrowser/#/R-RNO-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Rattus norvegicus 29108 R-RNO-936883 https://reactome.org/PathwayBrowser/#/R-RNO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Rattus norvegicus 29108 R-RNO-9603302 https://reactome.org/PathwayBrowser/#/R-RNO-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Rattus norvegicus 29108 R-RNO-9617322 https://reactome.org/PathwayBrowser/#/R-RNO-9617322 Calm1:4xCa2+ binds GluN1:GluN2 (Grin1:Grin2) NMDA receptors and displaces Actn2 TAS Rattus norvegicus 29108 R-RNO-9617504 https://reactome.org/PathwayBrowser/#/R-RNO-9617504 Calmodulin-activated adenylate cyclases Adcy1 and Adcy8 generate cAMP TAS Rattus norvegicus 29108 R-RNO-9617562 https://reactome.org/PathwayBrowser/#/R-RNO-9617562 Activated calmodulin binds Adcy8 TAS Rattus norvegicus 29108 R-RNO-9618605 https://reactome.org/PathwayBrowser/#/R-RNO-9618605 CaMKII binds activated calmodulin TAS Rattus norvegicus 29108 R-RNO-9618616 https://reactome.org/PathwayBrowser/#/R-RNO-9618616 CaMKII autophosphorylates TAS Rattus norvegicus 29108 R-RNO-9618659 https://reactome.org/PathwayBrowser/#/R-RNO-9618659 CaMKII binds activated GluN1:GluN2B (Grin1:Grin2b) NMDA receptor TAS Rattus norvegicus 29108 R-RNO-9618816 https://reactome.org/PathwayBrowser/#/R-RNO-9618816 Calcium binds calmodulin at the synapse TAS Rattus norvegicus 29108 R-RNO-9618839 https://reactome.org/PathwayBrowser/#/R-RNO-9618839 CaM-bound CaMKII-gamma enters the nucleus TAS Rattus norvegicus 29108 R-RNO-9618855 https://reactome.org/PathwayBrowser/#/R-RNO-9618855 Activated calmodulin dissociates from CaMKII gamma TAS Rattus norvegicus 29108 R-RNO-9619165 https://reactome.org/PathwayBrowser/#/R-RNO-9619165 Camkk1 phosphorylates Camk4 TAS Rattus norvegicus 29108 R-RNO-9619355 https://reactome.org/PathwayBrowser/#/R-RNO-9619355 CaMKK autophosphorylates in the cytosol IEA Rattus norvegicus 29108 R-RNO-9619376 https://reactome.org/PathwayBrowser/#/R-RNO-9619376 CAMK1 binds calmodulin IEA Rattus norvegicus 29108 R-RNO-9619441 https://reactome.org/PathwayBrowser/#/R-RNO-9619441 Ppm1e dephosphorylates Camk4 TAS Rattus norvegicus 29108 R-RNO-9619772 https://reactome.org/PathwayBrowser/#/R-RNO-9619772 Camk1 phosphorylates Arhgef7 TAS Rattus norvegicus 29108 R-RNO-9620437 https://reactome.org/PathwayBrowser/#/R-RNO-9620437 Camk2 phosphorylates GluA1 (Gria1) TAS Rattus norvegicus 29108 R-RNO-9626848 https://reactome.org/PathwayBrowser/#/R-RNO-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Rattus norvegicus 29108 R-RNO-9648983 https://reactome.org/PathwayBrowser/#/R-RNO-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Rattus norvegicus 29108 R-RNO-9653585 https://reactome.org/PathwayBrowser/#/R-RNO-9653585 S-Farn-Me KRAS4B binds calmodulin IEA Rattus norvegicus 29108 R-RNO-9654521 https://reactome.org/PathwayBrowser/#/R-RNO-9654521 Calmodulin dissociates KRAS4B from the plasma membrane IEA Rattus norvegicus 29108 R-RNO-9654523 https://reactome.org/PathwayBrowser/#/R-RNO-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Rattus norvegicus 29108 R-RNO-9654525 https://reactome.org/PathwayBrowser/#/R-RNO-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ IEA Rattus norvegicus 29108 R-RNO-9654533 https://reactome.org/PathwayBrowser/#/R-RNO-9654533 KRAS4B recycles to the plasma membrane IEA Rattus norvegicus 29108 R-RNO-9657599 https://reactome.org/PathwayBrowser/#/R-RNO-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Rattus norvegicus 29108 R-RNO-9657603 https://reactome.org/PathwayBrowser/#/R-RNO-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Rattus norvegicus 29108 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 29108 R-RNO-9657608 https://reactome.org/PathwayBrowser/#/R-RNO-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Rattus norvegicus 29108 R-RNO-9659568 https://reactome.org/PathwayBrowser/#/R-RNO-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Rattus norvegicus 29108 R-RNO-9664221 https://reactome.org/PathwayBrowser/#/R-RNO-9664221 Atp2b1 (Pmca1) transports Ca2+ from the cytosol to the extracellular region TAS Rattus norvegicus 29108 R-RNO-9664232 https://reactome.org/PathwayBrowser/#/R-RNO-9664232 Atp2b2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region TAS Rattus norvegicus 29108 R-RNO-9665067 https://reactome.org/PathwayBrowser/#/R-RNO-9665067 MET channel transports cations from the extracellular region into the cytosol of stereocilia TAS Rattus norvegicus 29108 R-RNO-9667806 https://reactome.org/PathwayBrowser/#/R-RNO-9667806 Kcnma1:Kcnmb1 transports potassium ions from the cytosol to the extracellular region TAS Rattus norvegicus 29108 R-RNO-9667850 https://reactome.org/PathwayBrowser/#/R-RNO-9667850 Chrna9:Chrna10:AcCho transports calcium ions from the extracellular region to the cytosol TAS Rattus norvegicus 29108 R-RNO-9701055 https://reactome.org/PathwayBrowser/#/R-RNO-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Rattus norvegicus 29108 R-RNO-9701141 https://reactome.org/PathwayBrowser/#/R-RNO-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Rattus norvegicus 29108 R-RNO-9707186 https://reactome.org/PathwayBrowser/#/R-RNO-9707186 ALOX5 binds ALOX5 inhibitors IEA Rattus norvegicus 29108 R-RNO-9708859 https://reactome.org/PathwayBrowser/#/R-RNO-9708859 Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it IEA Rattus norvegicus 29108 R-RNO-9713740 https://reactome.org/PathwayBrowser/#/R-RNO-9713740 cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol TAS Rattus norvegicus 29108 R-RNO-9717215 https://reactome.org/PathwayBrowser/#/R-RNO-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Rattus norvegicus 29108 R-RNO-975311 https://reactome.org/PathwayBrowser/#/R-RNO-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Rattus norvegicus 29108 R-RNO-9756177 https://reactome.org/PathwayBrowser/#/R-RNO-9756177 PON1,3 hydrolyse ATVL to ATV IEA Rattus norvegicus 29108 R-RNO-9840949 https://reactome.org/PathwayBrowser/#/R-RNO-9840949 ARSA removes sulfate from SM3 IEA Rattus norvegicus 29108 R-RNO-9853499 https://reactome.org/PathwayBrowser/#/R-RNO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 29108 R-RNO-9853512 https://reactome.org/PathwayBrowser/#/R-RNO-9853512 DLST transfers succinyl to CoA IEA Rattus norvegicus 29108 R-SCE-111881 https://reactome.org/PathwayBrowser/#/R-SCE-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Saccharomyces cerevisiae 29108 R-SCE-111883 https://reactome.org/PathwayBrowser/#/R-SCE-111883 Hydrolysis of phosphatidylcholine IEA Saccharomyces cerevisiae 29108 R-SCE-114553 https://reactome.org/PathwayBrowser/#/R-SCE-114553 Activation of conventional Protein Kinase C IEA Saccharomyces cerevisiae 29108 R-SCE-114683 https://reactome.org/PathwayBrowser/#/R-SCE-114683 Phosphorylation of Platelet Sec-1 IEA Saccharomyces cerevisiae 29108 R-SCE-114684 https://reactome.org/PathwayBrowser/#/R-SCE-114684 Phosphorylation of Syntaxin-4 IEA Saccharomyces cerevisiae 29108 R-SCE-1168373 https://reactome.org/PathwayBrowser/#/R-SCE-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Saccharomyces cerevisiae 29108 R-SCE-1482604 https://reactome.org/PathwayBrowser/#/R-SCE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Saccharomyces cerevisiae 29108 R-SCE-1482612 https://reactome.org/PathwayBrowser/#/R-SCE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 29108 R-SCE-1482656 https://reactome.org/PathwayBrowser/#/R-SCE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Saccharomyces cerevisiae 29108 R-SCE-1482685 https://reactome.org/PathwayBrowser/#/R-SCE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 29108 R-SCE-1482759 https://reactome.org/PathwayBrowser/#/R-SCE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Saccharomyces cerevisiae 29108 R-SCE-1482771 https://reactome.org/PathwayBrowser/#/R-SCE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Saccharomyces cerevisiae 29108 R-SCE-1482825 https://reactome.org/PathwayBrowser/#/R-SCE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Saccharomyces cerevisiae 29108 R-SCE-1482828 https://reactome.org/PathwayBrowser/#/R-SCE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Saccharomyces cerevisiae 29108 R-SCE-1482856 https://reactome.org/PathwayBrowser/#/R-SCE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Saccharomyces cerevisiae 29108 R-SCE-1482862 https://reactome.org/PathwayBrowser/#/R-SCE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Saccharomyces cerevisiae 29108 R-SCE-1482884 https://reactome.org/PathwayBrowser/#/R-SCE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Saccharomyces cerevisiae 29108 R-SCE-1482897 https://reactome.org/PathwayBrowser/#/R-SCE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Saccharomyces cerevisiae 29108 R-SCE-1482900 https://reactome.org/PathwayBrowser/#/R-SCE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Saccharomyces cerevisiae 29108 R-SCE-1497784 https://reactome.org/PathwayBrowser/#/R-SCE-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Saccharomyces cerevisiae 29108 R-SCE-1497796 https://reactome.org/PathwayBrowser/#/R-SCE-1497796 BH2 binding can lead to eNOS uncoupling IEA Saccharomyces cerevisiae 29108 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 29108 R-SCE-1855177 https://reactome.org/PathwayBrowser/#/R-SCE-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Saccharomyces cerevisiae 29108 R-SCE-1855214 https://reactome.org/PathwayBrowser/#/R-SCE-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Saccharomyces cerevisiae 29108 R-SCE-1855221 https://reactome.org/PathwayBrowser/#/R-SCE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Saccharomyces cerevisiae 29108 R-SCE-202111 https://reactome.org/PathwayBrowser/#/R-SCE-202111 AKT1 phosphorylates eNOS IEA Saccharomyces cerevisiae 29108 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 29108 R-SCE-2586748 https://reactome.org/PathwayBrowser/#/R-SCE-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ IEA Saccharomyces cerevisiae 29108 R-SCE-2684901 https://reactome.org/PathwayBrowser/#/R-SCE-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Saccharomyces cerevisiae 29108 R-SCE-3295579 https://reactome.org/PathwayBrowser/#/R-SCE-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Saccharomyces cerevisiae 29108 R-SCE-354173 https://reactome.org/PathwayBrowser/#/R-SCE-354173 Activation of Rap1 by cytosolic GEFs IEA Saccharomyces cerevisiae 29108 R-SCE-372448 https://reactome.org/PathwayBrowser/#/R-SCE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Saccharomyces cerevisiae 29108 R-SCE-418309 https://reactome.org/PathwayBrowser/#/R-SCE-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Saccharomyces cerevisiae 29108 R-SCE-425822 https://reactome.org/PathwayBrowser/#/R-SCE-425822 K+-independent Li+/Ca2+ exchanger transport IEA Saccharomyces cerevisiae 29108 R-SCE-428262 https://reactome.org/PathwayBrowser/#/R-SCE-428262 ACER3 hydrolyzes phytoceramide IEA Saccharomyces cerevisiae 29108 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 29108 R-SCE-5218813 https://reactome.org/PathwayBrowser/#/R-SCE-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Saccharomyces cerevisiae 29108 R-SCE-5218823 https://reactome.org/PathwayBrowser/#/R-SCE-5218823 PKC phosphorylates sphingosine kinase 1 IEA Saccharomyces cerevisiae 29108 R-SCE-5223304 https://reactome.org/PathwayBrowser/#/R-SCE-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Saccharomyces cerevisiae 29108 R-SCE-5694018 https://reactome.org/PathwayBrowser/#/R-SCE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Saccharomyces cerevisiae 29108 R-SCE-71401 https://reactome.org/PathwayBrowser/#/R-SCE-71401 OGDH dimer decarboxylates 2-OG IEA Saccharomyces cerevisiae 29108 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 29108 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 29108 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 29108 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 29108 R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 29108 R-SCE-8949688 https://reactome.org/PathwayBrowser/#/R-SCE-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Saccharomyces cerevisiae 29108 R-SCE-936883 https://reactome.org/PathwayBrowser/#/R-SCE-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Saccharomyces cerevisiae 29108 R-SCE-9659568 https://reactome.org/PathwayBrowser/#/R-SCE-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Saccharomyces cerevisiae 29108 R-SCE-9701055 https://reactome.org/PathwayBrowser/#/R-SCE-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 29108 R-SCE-9701141 https://reactome.org/PathwayBrowser/#/R-SCE-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 29108 R-SCE-9853499 https://reactome.org/PathwayBrowser/#/R-SCE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 29108 R-SCE-9853512 https://reactome.org/PathwayBrowser/#/R-SCE-9853512 DLST transfers succinyl to CoA IEA Saccharomyces cerevisiae 29108 R-SPO-111881 https://reactome.org/PathwayBrowser/#/R-SPO-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Schizosaccharomyces pombe 29108 R-SPO-111883 https://reactome.org/PathwayBrowser/#/R-SPO-111883 Hydrolysis of phosphatidylcholine IEA Schizosaccharomyces pombe 29108 R-SPO-114553 https://reactome.org/PathwayBrowser/#/R-SPO-114553 Activation of conventional Protein Kinase C IEA Schizosaccharomyces pombe 29108 R-SPO-114683 https://reactome.org/PathwayBrowser/#/R-SPO-114683 Phosphorylation of Platelet Sec-1 IEA Schizosaccharomyces pombe 29108 R-SPO-114684 https://reactome.org/PathwayBrowser/#/R-SPO-114684 Phosphorylation of Syntaxin-4 IEA Schizosaccharomyces pombe 29108 R-SPO-1168373 https://reactome.org/PathwayBrowser/#/R-SPO-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Schizosaccharomyces pombe 29108 R-SPO-1482604 https://reactome.org/PathwayBrowser/#/R-SPO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Schizosaccharomyces pombe 29108 R-SPO-1482612 https://reactome.org/PathwayBrowser/#/R-SPO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 29108 R-SPO-1482656 https://reactome.org/PathwayBrowser/#/R-SPO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Schizosaccharomyces pombe 29108 R-SPO-1482685 https://reactome.org/PathwayBrowser/#/R-SPO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 29108 R-SPO-1482759 https://reactome.org/PathwayBrowser/#/R-SPO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Schizosaccharomyces pombe 29108 R-SPO-1482771 https://reactome.org/PathwayBrowser/#/R-SPO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Schizosaccharomyces pombe 29108 R-SPO-1482825 https://reactome.org/PathwayBrowser/#/R-SPO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Schizosaccharomyces pombe 29108 R-SPO-1482828 https://reactome.org/PathwayBrowser/#/R-SPO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Schizosaccharomyces pombe 29108 R-SPO-1482856 https://reactome.org/PathwayBrowser/#/R-SPO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Schizosaccharomyces pombe 29108 R-SPO-1482862 https://reactome.org/PathwayBrowser/#/R-SPO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Schizosaccharomyces pombe 29108 R-SPO-1482884 https://reactome.org/PathwayBrowser/#/R-SPO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Schizosaccharomyces pombe 29108 R-SPO-1482897 https://reactome.org/PathwayBrowser/#/R-SPO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Schizosaccharomyces pombe 29108 R-SPO-1482900 https://reactome.org/PathwayBrowser/#/R-SPO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Schizosaccharomyces pombe 29108 R-SPO-1497784 https://reactome.org/PathwayBrowser/#/R-SPO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Schizosaccharomyces pombe 29108 R-SPO-1497796 https://reactome.org/PathwayBrowser/#/R-SPO-1497796 BH2 binding can lead to eNOS uncoupling IEA Schizosaccharomyces pombe 29108 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 29108 R-SPO-1606839 https://reactome.org/PathwayBrowser/#/R-SPO-1606839 ARSC hydrolyzes steroid sulfates IEA Schizosaccharomyces pombe 29108 R-SPO-1855177 https://reactome.org/PathwayBrowser/#/R-SPO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Schizosaccharomyces pombe 29108 R-SPO-1855214 https://reactome.org/PathwayBrowser/#/R-SPO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Schizosaccharomyces pombe 29108 R-SPO-1855221 https://reactome.org/PathwayBrowser/#/R-SPO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Schizosaccharomyces pombe 29108 R-SPO-202111 https://reactome.org/PathwayBrowser/#/R-SPO-202111 AKT1 phosphorylates eNOS IEA Schizosaccharomyces pombe 29108 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 29108 R-SPO-202137 https://reactome.org/PathwayBrowser/#/R-SPO-202137 AKT1 binds eNOS complex via HSP90 IEA Schizosaccharomyces pombe 29108 R-SPO-2248891 https://reactome.org/PathwayBrowser/#/R-SPO-2248891 M6PR transports activated ARSA to the lysosome IEA Schizosaccharomyces pombe 29108 R-SPO-2586748 https://reactome.org/PathwayBrowser/#/R-SPO-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ IEA Schizosaccharomyces pombe 29108 R-SPO-2684901 https://reactome.org/PathwayBrowser/#/R-SPO-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Schizosaccharomyces pombe 29108 R-SPO-2730867 https://reactome.org/PathwayBrowser/#/R-SPO-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Schizosaccharomyces pombe 29108 R-SPO-2730872 https://reactome.org/PathwayBrowser/#/R-SPO-2730872 Activation of Calcineurin IEA Schizosaccharomyces pombe 29108 R-SPO-418309 https://reactome.org/PathwayBrowser/#/R-SPO-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Schizosaccharomyces pombe 29108 R-SPO-425822 https://reactome.org/PathwayBrowser/#/R-SPO-425822 K+-independent Li+/Ca2+ exchanger transport IEA Schizosaccharomyces pombe 29108 R-SPO-442749 https://reactome.org/PathwayBrowser/#/R-SPO-442749 CaMKK autophosphorylates in the nucleus IEA Schizosaccharomyces pombe 29108 R-SPO-4551465 https://reactome.org/PathwayBrowser/#/R-SPO-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Schizosaccharomyces pombe 29108 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 29108 R-SPO-5218813 https://reactome.org/PathwayBrowser/#/R-SPO-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Schizosaccharomyces pombe 29108 R-SPO-5218823 https://reactome.org/PathwayBrowser/#/R-SPO-5218823 PKC phosphorylates sphingosine kinase 1 IEA Schizosaccharomyces pombe 29108 R-SPO-5223304 https://reactome.org/PathwayBrowser/#/R-SPO-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Schizosaccharomyces pombe 29108 R-SPO-5626507 https://reactome.org/PathwayBrowser/#/R-SPO-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Schizosaccharomyces pombe 29108 R-SPO-5626549 https://reactome.org/PathwayBrowser/#/R-SPO-5626549 IQGAPs bind CALM1 IEA Schizosaccharomyces pombe 29108 R-SPO-5694018 https://reactome.org/PathwayBrowser/#/R-SPO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Schizosaccharomyces pombe 29108 R-SPO-71401 https://reactome.org/PathwayBrowser/#/R-SPO-71401 OGDH dimer decarboxylates 2-OG IEA Schizosaccharomyces pombe 29108 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 29108 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 29108 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 29108 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 29108 R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 29108 R-SPO-8949688 https://reactome.org/PathwayBrowser/#/R-SPO-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Schizosaccharomyces pombe 29108 R-SPO-936883 https://reactome.org/PathwayBrowser/#/R-SPO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Schizosaccharomyces pombe 29108 R-SPO-9619355 https://reactome.org/PathwayBrowser/#/R-SPO-9619355 CaMKK autophosphorylates in the cytosol IEA Schizosaccharomyces pombe 29108 R-SPO-9659568 https://reactome.org/PathwayBrowser/#/R-SPO-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Schizosaccharomyces pombe 29108 R-SPO-9840949 https://reactome.org/PathwayBrowser/#/R-SPO-9840949 ARSA removes sulfate from SM3 IEA Schizosaccharomyces pombe 29108 R-SPO-9853499 https://reactome.org/PathwayBrowser/#/R-SPO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 29108 R-SPO-9853512 https://reactome.org/PathwayBrowser/#/R-SPO-9853512 DLST transfers succinyl to CoA IEA Schizosaccharomyces pombe 29108 R-SSC-111881 https://reactome.org/PathwayBrowser/#/R-SSC-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Sus scrofa 29108 R-SSC-111883 https://reactome.org/PathwayBrowser/#/R-SSC-111883 Hydrolysis of phosphatidylcholine IEA Sus scrofa 29108 R-SSC-111930 https://reactome.org/PathwayBrowser/#/R-SSC-111930 Adenylate cyclase produces cAMP IEA Sus scrofa 29108 R-SSC-111956 https://reactome.org/PathwayBrowser/#/R-SSC-111956 Calmodulin activates Cam-PDE 1 IEA Sus scrofa 29108 R-SSC-111966 https://reactome.org/PathwayBrowser/#/R-SSC-111966 GRK2 binds CALM1:4Ca2+ IEA Sus scrofa 29108 R-SSC-111970 https://reactome.org/PathwayBrowser/#/R-SSC-111970 PKC phosphorylates GRK2 IEA Sus scrofa 29108 R-SSC-114553 https://reactome.org/PathwayBrowser/#/R-SSC-114553 Activation of conventional Protein Kinase C IEA Sus scrofa 29108 R-SSC-114683 https://reactome.org/PathwayBrowser/#/R-SSC-114683 Phosphorylation of Platelet Sec-1 IEA Sus scrofa 29108 R-SSC-114684 https://reactome.org/PathwayBrowser/#/R-SSC-114684 Phosphorylation of Syntaxin-4 IEA Sus scrofa 29108 R-SSC-114697 https://reactome.org/PathwayBrowser/#/R-SSC-114697 Activated thrombin (factor IIa) cleaves PAR3,4, activating them IEA Sus scrofa 29108 R-SSC-1168376 https://reactome.org/PathwayBrowser/#/R-SSC-1168376 STIM1 oligomerizes IEA Sus scrofa 29108 R-SSC-1183128 https://reactome.org/PathwayBrowser/#/R-SSC-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Sus scrofa 29108 R-SSC-139854 https://reactome.org/PathwayBrowser/#/R-SSC-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Sus scrofa 29108 R-SSC-139855 https://reactome.org/PathwayBrowser/#/R-SSC-139855 P2X1-mediated entry of Ca++ from plasma IEA Sus scrofa 29108 R-SSC-139941 https://reactome.org/PathwayBrowser/#/R-SSC-139941 Binding of IP3 to IP3 receptor IEA Sus scrofa 29108 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 29108 R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 29108 R-SSC-140686 https://reactome.org/PathwayBrowser/#/R-SSC-140686 factor Va + factor Xa -> Va:Xa complex (prothrombinase) IEA Sus scrofa 29108 R-SSC-140696 https://reactome.org/PathwayBrowser/#/R-SSC-140696 factor V -> factor Va + factor V activation peptide IEA Sus scrofa 29108 R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 29108 R-SSC-140736 https://reactome.org/PathwayBrowser/#/R-SSC-140736 factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) IEA Sus scrofa 29108 R-SSC-140748 https://reactome.org/PathwayBrowser/#/R-SSC-140748 tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex IEA Sus scrofa 29108 R-SSC-140769 https://reactome.org/PathwayBrowser/#/R-SSC-140769 factor VII -> factor VIIa IEA Sus scrofa 29108 R-SSC-140777 https://reactome.org/PathwayBrowser/#/R-SSC-140777 factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) IEA Sus scrofa 29108 R-SSC-140783 https://reactome.org/PathwayBrowser/#/R-SSC-140783 tissue factor (TF) + factor VII (F7) -> TF:F7 complex IEA Sus scrofa 29108 R-SSC-140791 https://reactome.org/PathwayBrowser/#/R-SSC-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Sus scrofa 29108 R-SSC-140823 https://reactome.org/PathwayBrowser/#/R-SSC-140823 factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) IEA Sus scrofa 29108 R-SSC-140825 https://reactome.org/PathwayBrowser/#/R-SSC-140825 TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa IEA Sus scrofa 29108 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 29108 R-SSC-140847 https://reactome.org/PathwayBrowser/#/R-SSC-140847 factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain IEA Sus scrofa 29108 R-SSC-140851 https://reactome.org/PathwayBrowser/#/R-SSC-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Sus scrofa 29108 R-SSC-140870 https://reactome.org/PathwayBrowser/#/R-SSC-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Sus scrofa 29108 R-SSC-140872 https://reactome.org/PathwayBrowser/#/R-SSC-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Sus scrofa 29108 R-SSC-141026 https://reactome.org/PathwayBrowser/#/R-SSC-141026 Activated protein C cleaves factor Va to factor Vi intermediate form IEA Sus scrofa 29108 R-SSC-141040 https://reactome.org/PathwayBrowser/#/R-SSC-141040 Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C IEA Sus scrofa 29108 R-SSC-141046 https://reactome.org/PathwayBrowser/#/R-SSC-141046 activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin IEA Sus scrofa 29108 R-SSC-1482604 https://reactome.org/PathwayBrowser/#/R-SSC-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Sus scrofa 29108 R-SSC-1482612 https://reactome.org/PathwayBrowser/#/R-SSC-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 29108 R-SSC-1482656 https://reactome.org/PathwayBrowser/#/R-SSC-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Sus scrofa 29108 R-SSC-1482679 https://reactome.org/PathwayBrowser/#/R-SSC-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Sus scrofa 29108 R-SSC-1482685 https://reactome.org/PathwayBrowser/#/R-SSC-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 29108 R-SSC-1482759 https://reactome.org/PathwayBrowser/#/R-SSC-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Sus scrofa 29108 R-SSC-1482771 https://reactome.org/PathwayBrowser/#/R-SSC-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Sus scrofa 29108 R-SSC-1482776 https://reactome.org/PathwayBrowser/#/R-SSC-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Sus scrofa 29108 R-SSC-1482816 https://reactome.org/PathwayBrowser/#/R-SSC-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Sus scrofa 29108 R-SSC-1482825 https://reactome.org/PathwayBrowser/#/R-SSC-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Sus scrofa 29108 R-SSC-1482828 https://reactome.org/PathwayBrowser/#/R-SSC-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Sus scrofa 29108 R-SSC-1482856 https://reactome.org/PathwayBrowser/#/R-SSC-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Sus scrofa 29108 R-SSC-1482862 https://reactome.org/PathwayBrowser/#/R-SSC-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Sus scrofa 29108 R-SSC-1482868 https://reactome.org/PathwayBrowser/#/R-SSC-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Sus scrofa 29108 R-SSC-1482884 https://reactome.org/PathwayBrowser/#/R-SSC-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Sus scrofa 29108 R-SSC-1482887 https://reactome.org/PathwayBrowser/#/R-SSC-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Sus scrofa 29108 R-SSC-1482897 https://reactome.org/PathwayBrowser/#/R-SSC-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Sus scrofa 29108 R-SSC-1482900 https://reactome.org/PathwayBrowser/#/R-SSC-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Sus scrofa 29108 R-SSC-1482907 https://reactome.org/PathwayBrowser/#/R-SSC-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Sus scrofa 29108 R-SSC-1497784 https://reactome.org/PathwayBrowser/#/R-SSC-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Sus scrofa 29108 R-SSC-1497796 https://reactome.org/PathwayBrowser/#/R-SSC-1497796 BH2 binding can lead to eNOS uncoupling IEA Sus scrofa 29108 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 29108 R-SSC-158333 https://reactome.org/PathwayBrowser/#/R-SSC-158333 factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) IEA Sus scrofa 29108 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 29108 R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa 29108 R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa 29108 R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa 29108 R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa 29108 R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa 29108 R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa 29108 R-SSC-1606789 https://reactome.org/PathwayBrowser/#/R-SSC-1606789 ARSB hydrolyses DS IEA Sus scrofa 29108 R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 29108 R-SSC-1606839 https://reactome.org/PathwayBrowser/#/R-SSC-1606839 ARSC hydrolyzes steroid sulfates IEA Sus scrofa 29108 R-SSC-1614362 https://reactome.org/PathwayBrowser/#/R-SSC-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Sus scrofa 29108 R-SSC-166721 https://reactome.org/PathwayBrowser/#/R-SSC-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa IEA Sus scrofa 29108 R-SSC-166726 https://reactome.org/PathwayBrowser/#/R-SSC-166726 Activation of MASPs IEA Sus scrofa 29108 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa 29108 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa 29108 R-SSC-1675928 https://reactome.org/PathwayBrowser/#/R-SSC-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Sus scrofa 29108 R-SSC-1675939 https://reactome.org/PathwayBrowser/#/R-SSC-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Sus scrofa 29108 R-SSC-1675961 https://reactome.org/PathwayBrowser/#/R-SSC-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Sus scrofa 29108 R-SSC-1676024 https://reactome.org/PathwayBrowser/#/R-SSC-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Sus scrofa 29108 R-SSC-1676109 https://reactome.org/PathwayBrowser/#/R-SSC-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Sus scrofa 29108 R-SSC-1676206 https://reactome.org/PathwayBrowser/#/R-SSC-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Sus scrofa 29108 R-SSC-1678650 https://reactome.org/PathwayBrowser/#/R-SSC-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Sus scrofa 29108 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa 29108 R-SSC-1793182 https://reactome.org/PathwayBrowser/#/R-SSC-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Sus scrofa 29108 R-SSC-1793207 https://reactome.org/PathwayBrowser/#/R-SSC-1793207 ARSB hydrolyses C4S/C6S chains IEA Sus scrofa 29108 R-SSC-1855153 https://reactome.org/PathwayBrowser/#/R-SSC-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Sus scrofa 29108 R-SSC-1855177 https://reactome.org/PathwayBrowser/#/R-SSC-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Sus scrofa 29108 R-SSC-1855214 https://reactome.org/PathwayBrowser/#/R-SSC-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Sus scrofa 29108 R-SSC-1855221 https://reactome.org/PathwayBrowser/#/R-SSC-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Sus scrofa 29108 R-SSC-187020 https://reactome.org/PathwayBrowser/#/R-SSC-187020 Part of pro-beta-NGF is processed to mature beta-NGF IEA Sus scrofa 29108 R-SSC-202110 https://reactome.org/PathwayBrowser/#/R-SSC-202110 eNOS:Caveolin-1 complex binds to CaM IEA Sus scrofa 29108 R-SSC-202111 https://reactome.org/PathwayBrowser/#/R-SSC-202111 AKT1 phosphorylates eNOS IEA Sus scrofa 29108 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 29108 R-SSC-202129 https://reactome.org/PathwayBrowser/#/R-SSC-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Sus scrofa 29108 R-SSC-202144 https://reactome.org/PathwayBrowser/#/R-SSC-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Sus scrofa 29108 R-SSC-2025890 https://reactome.org/PathwayBrowser/#/R-SSC-2025890 Calcineurin binds NFATC1,2,3 IEA Sus scrofa 29108 R-SSC-2089943 https://reactome.org/PathwayBrowser/#/R-SSC-2089943 TRPC1 translocates calcium from the extracellular region to the cytosol IEA Sus scrofa 29108 R-SSC-210420 https://reactome.org/PathwayBrowser/#/R-SSC-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Sus scrofa 29108 R-SSC-210430 https://reactome.org/PathwayBrowser/#/R-SSC-210430 Release of L-Glutamate at the synapse IEA Sus scrofa 29108 R-SSC-2160884 https://reactome.org/PathwayBrowser/#/R-SSC-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Sus scrofa 29108 R-SSC-2160892 https://reactome.org/PathwayBrowser/#/R-SSC-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Sus scrofa 29108 R-SSC-2161768 https://reactome.org/PathwayBrowser/#/R-SSC-2161768 EXA4 is converted to EXC4 by LTC4S IEA Sus scrofa 29108 R-SSC-2161907 https://reactome.org/PathwayBrowser/#/R-SSC-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Sus scrofa 29108 R-SSC-2161917 https://reactome.org/PathwayBrowser/#/R-SSC-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Sus scrofa 29108 R-SSC-2248891 https://reactome.org/PathwayBrowser/#/R-SSC-2248891 M6PR transports activated ARSA to the lysosome IEA Sus scrofa 29108 R-SSC-2424243 https://reactome.org/PathwayBrowser/#/R-SSC-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Sus scrofa 29108 R-SSC-2514867 https://reactome.org/PathwayBrowser/#/R-SSC-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Sus scrofa 29108 R-SSC-2534359 https://reactome.org/PathwayBrowser/#/R-SSC-2534359 CatSper Channel Mediated Calcium Transport IEA Sus scrofa 29108 R-SSC-2581474 https://reactome.org/PathwayBrowser/#/R-SSC-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Sus scrofa 29108 R-SSC-2586748 https://reactome.org/PathwayBrowser/#/R-SSC-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ IEA Sus scrofa 29108 R-SSC-264976 https://reactome.org/PathwayBrowser/#/R-SSC-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium IEA Sus scrofa 29108 R-SSC-265153 https://reactome.org/PathwayBrowser/#/R-SSC-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Sus scrofa 29108 R-SSC-265296 https://reactome.org/PathwayBrowser/#/R-SSC-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Sus scrofa 29108 R-SSC-265301 https://reactome.org/PathwayBrowser/#/R-SSC-265301 Corticotropin cleavage from POMC IEA Sus scrofa 29108 R-SSC-265645 https://reactome.org/PathwayBrowser/#/R-SSC-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Sus scrofa 29108 R-SSC-266050 https://reactome.org/PathwayBrowser/#/R-SSC-266050 LTA4 is converted to LTC4 by LTC4S IEA Sus scrofa 29108 R-SSC-266051 https://reactome.org/PathwayBrowser/#/R-SSC-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Sus scrofa 29108 R-SSC-2684901 https://reactome.org/PathwayBrowser/#/R-SSC-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Sus scrofa 29108 R-SSC-2685505 https://reactome.org/PathwayBrowser/#/R-SSC-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Sus scrofa 29108 R-SSC-2730664 https://reactome.org/PathwayBrowser/#/R-SSC-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Sus scrofa 29108 R-SSC-2730849 https://reactome.org/PathwayBrowser/#/R-SSC-2730849 Calcineurin binds and dephosphorylates NFAT IEA Sus scrofa 29108 R-SSC-2730867 https://reactome.org/PathwayBrowser/#/R-SSC-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Sus scrofa 29108 R-SSC-2730872 https://reactome.org/PathwayBrowser/#/R-SSC-2730872 Activation of Calcineurin IEA Sus scrofa 29108 R-SSC-2744242 https://reactome.org/PathwayBrowser/#/R-SSC-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Sus scrofa 29108 R-SSC-2744361 https://reactome.org/PathwayBrowser/#/R-SSC-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Sus scrofa 29108 R-SSC-2855020 https://reactome.org/PathwayBrowser/#/R-SSC-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Sus scrofa 29108 R-SSC-2855054 https://reactome.org/PathwayBrowser/#/R-SSC-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Sus scrofa 29108 R-SSC-2855125 https://reactome.org/PathwayBrowser/#/R-SSC-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Sus scrofa 29108 R-SSC-3229181 https://reactome.org/PathwayBrowser/#/R-SSC-3229181 CALM1:Ca2+ binds CNG channel IEA Sus scrofa 29108 R-SSC-3295579 https://reactome.org/PathwayBrowser/#/R-SSC-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Sus scrofa 29108 R-SSC-354073 https://reactome.org/PathwayBrowser/#/R-SSC-354073 Autophosphorylation of PTK2 at Y397 IEA Sus scrofa 29108 R-SSC-354087 https://reactome.org/PathwayBrowser/#/R-SSC-354087 Recruitment of GRB2 to p-PTK2 IEA Sus scrofa 29108 R-SSC-354124 https://reactome.org/PathwayBrowser/#/R-SSC-354124 Phosphorylation of pPTK2 by SRC IEA Sus scrofa 29108 R-SSC-354149 https://reactome.org/PathwayBrowser/#/R-SSC-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Sus scrofa 29108 R-SSC-354165 https://reactome.org/PathwayBrowser/#/R-SSC-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Sus scrofa 29108 R-SSC-354173 https://reactome.org/PathwayBrowser/#/R-SSC-354173 Activation of Rap1 by cytosolic GEFs IEA Sus scrofa 29108 R-SSC-372448 https://reactome.org/PathwayBrowser/#/R-SSC-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Sus scrofa 29108 R-SSC-372693 https://reactome.org/PathwayBrowser/#/R-SSC-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Sus scrofa 29108 R-SSC-372697 https://reactome.org/PathwayBrowser/#/R-SSC-372697 Crk binding to p130cas IEA Sus scrofa 29108 R-SSC-372705 https://reactome.org/PathwayBrowser/#/R-SSC-372705 Recruitment of BCAR1 to PTK2 complex IEA Sus scrofa 29108 R-SSC-377640 https://reactome.org/PathwayBrowser/#/R-SSC-377640 Autophosphorylation of SRC IEA Sus scrofa 29108 R-SSC-377641 https://reactome.org/PathwayBrowser/#/R-SSC-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Sus scrofa 29108 R-SSC-377643 https://reactome.org/PathwayBrowser/#/R-SSC-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Sus scrofa 29108 R-SSC-377644 https://reactome.org/PathwayBrowser/#/R-SSC-377644 Release of CSK from SRC IEA Sus scrofa 29108 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 29108 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 29108 R-SSC-3827958 https://reactome.org/PathwayBrowser/#/R-SSC-3827958 E-cadherin degradation by MMP9, KLK7 IEA Sus scrofa 29108 R-SSC-389463 https://reactome.org/PathwayBrowser/#/R-SSC-389463 Proteinase-activated receptors can bind thrombin IEA Sus scrofa 29108 R-SSC-390593 https://reactome.org/PathwayBrowser/#/R-SSC-390593 ATP Hydrolysis By Myosin IEA Sus scrofa 29108 R-SSC-390595 https://reactome.org/PathwayBrowser/#/R-SSC-390595 Calcium Binds Troponin-C IEA Sus scrofa 29108 R-SSC-390597 https://reactome.org/PathwayBrowser/#/R-SSC-390597 Release Of ADP From Myosin IEA Sus scrofa 29108 R-SSC-390598 https://reactome.org/PathwayBrowser/#/R-SSC-390598 Myosin Binds ATP IEA Sus scrofa 29108 R-SSC-399712 https://reactome.org/PathwayBrowser/#/R-SSC-399712 Activation of Ca permeable AMPA receptors IEA Sus scrofa 29108 R-SSC-416639 https://reactome.org/PathwayBrowser/#/R-SSC-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Sus scrofa 29108 R-SSC-418309 https://reactome.org/PathwayBrowser/#/R-SSC-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Sus scrofa 29108 R-SSC-418365 https://reactome.org/PathwayBrowser/#/R-SSC-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Sus scrofa 29108 R-SSC-419001 https://reactome.org/PathwayBrowser/#/R-SSC-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Sus scrofa 29108 R-SSC-420724 https://reactome.org/PathwayBrowser/#/R-SSC-420724 CASR binds Ca2+ IEA Sus scrofa 29108 R-SSC-420739 https://reactome.org/PathwayBrowser/#/R-SSC-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Sus scrofa 29108 R-SSC-421007 https://reactome.org/PathwayBrowser/#/R-SSC-421007 Endocytosis of Ca impermeable AMPA receptors IEA Sus scrofa 29108 R-SSC-422021 https://reactome.org/PathwayBrowser/#/R-SSC-422021 PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin IEA Sus scrofa 29108 R-SSC-4224014 https://reactome.org/PathwayBrowser/#/R-SSC-4224014 E-cadherin degradation by ADAM10, ADAM15 IEA Sus scrofa 29108 R-SSC-425661 https://reactome.org/PathwayBrowser/#/R-SSC-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Sus scrofa 29108 R-SSC-425678 https://reactome.org/PathwayBrowser/#/R-SSC-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Sus scrofa 29108 R-SSC-425822 https://reactome.org/PathwayBrowser/#/R-SSC-425822 K+-independent Li+/Ca2+ exchanger transport IEA Sus scrofa 29108 R-SSC-426223 https://reactome.org/PathwayBrowser/#/R-SSC-426223 Cation influx mediated by TRPC3/6/7 IEA Sus scrofa 29108 R-SSC-427910 https://reactome.org/PathwayBrowser/#/R-SSC-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Sus scrofa 29108 R-SSC-428262 https://reactome.org/PathwayBrowser/#/R-SSC-428262 ACER3 hydrolyzes phytoceramide IEA Sus scrofa 29108 R-SSC-429016 https://reactome.org/PathwayBrowser/#/R-SSC-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Sus scrofa 29108 R-SSC-429415 https://reactome.org/PathwayBrowser/#/R-SSC-429415 SYK binds to integrin alphaIIb beta3 IEA Sus scrofa 29108 R-SSC-429441 https://reactome.org/PathwayBrowser/#/R-SSC-429441 SYK activation by SRC IEA Sus scrofa 29108 R-SSC-429529 https://reactome.org/PathwayBrowser/#/R-SSC-429529 Thrombin binding to GP1b:IX:V IEA Sus scrofa 29108 R-SSC-432164 https://reactome.org/PathwayBrowser/#/R-SSC-432164 Ca2+ influx into the post-synaptic cell IEA Sus scrofa 29108 R-SSC-4332358 https://reactome.org/PathwayBrowser/#/R-SSC-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Sus scrofa 29108 R-SSC-4332359 https://reactome.org/PathwayBrowser/#/R-SSC-4332359 Active calmodulin binds CAMK2 IEA Sus scrofa 29108 R-SSC-4332363 https://reactome.org/PathwayBrowser/#/R-SSC-4332363 Autophosphorylation and activation of CAMK2 IEA Sus scrofa 29108 R-SSC-438037 https://reactome.org/PathwayBrowser/#/R-SSC-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Sus scrofa 29108 R-SSC-442749 https://reactome.org/PathwayBrowser/#/R-SSC-442749 CaMKK autophosphorylates in the nucleus IEA Sus scrofa 29108 R-SSC-445699 https://reactome.org/PathwayBrowser/#/R-SSC-445699 ATP Hydrolysis By Myosin IEA Sus scrofa 29108 R-SSC-445700 https://reactome.org/PathwayBrowser/#/R-SSC-445700 Myosin Binds ATP IEA Sus scrofa 29108 R-SSC-445704 https://reactome.org/PathwayBrowser/#/R-SSC-445704 Calcium Binds Caldesmon IEA Sus scrofa 29108 R-SSC-445705 https://reactome.org/PathwayBrowser/#/R-SSC-445705 Release Of ADP From Myosin IEA Sus scrofa 29108 R-SSC-445797 https://reactome.org/PathwayBrowser/#/R-SSC-445797 MYLK (MLCK) Active Calmodulin Binding IEA Sus scrofa 29108 R-SSC-445813 https://reactome.org/PathwayBrowser/#/R-SSC-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Sus scrofa 29108 R-SSC-451311 https://reactome.org/PathwayBrowser/#/R-SSC-451311 Activation of Ca-permeable Kainate receptors IEA Sus scrofa 29108 R-SSC-4551451 https://reactome.org/PathwayBrowser/#/R-SSC-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Sus scrofa 29108 R-SSC-4551465 https://reactome.org/PathwayBrowser/#/R-SSC-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Sus scrofa 29108 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 29108 R-SSC-5138432 https://reactome.org/PathwayBrowser/#/R-SSC-5138432 DVL2 is phosphorylated by PKC IEA Sus scrofa 29108 R-SSC-5218813 https://reactome.org/PathwayBrowser/#/R-SSC-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Sus scrofa 29108 R-SSC-5218823 https://reactome.org/PathwayBrowser/#/R-SSC-5218823 PKC phosphorylates sphingosine kinase 1 IEA Sus scrofa 29108 R-SSC-5223304 https://reactome.org/PathwayBrowser/#/R-SSC-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Sus scrofa 29108 R-SSC-5229194 https://reactome.org/PathwayBrowser/#/R-SSC-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Sus scrofa 29108 R-SSC-5333671 https://reactome.org/PathwayBrowser/#/R-SSC-5333671 CLCAs self cleave IEA Sus scrofa 29108 R-SSC-5333678 https://reactome.org/PathwayBrowser/#/R-SSC-5333678 CPNEs bind PL IEA Sus scrofa 29108 R-SSC-5577213 https://reactome.org/PathwayBrowser/#/R-SSC-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Sus scrofa 29108 R-SSC-5578883 https://reactome.org/PathwayBrowser/#/R-SSC-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Sus scrofa 29108 R-SSC-5591040 https://reactome.org/PathwayBrowser/#/R-SSC-5591040 Activated protein C cleaves Factor Va intermediate form for Factor Va IEA Sus scrofa 29108 R-SSC-5591052 https://reactome.org/PathwayBrowser/#/R-SSC-5591052 PROCR binds Protein C IEA Sus scrofa 29108 R-SSC-5591086 https://reactome.org/PathwayBrowser/#/R-SSC-5591086 SERPINA5 binds activated protein C IEA Sus scrofa 29108 R-SSC-5602080 https://reactome.org/PathwayBrowser/#/R-SSC-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Sus scrofa 29108 R-SSC-5603467 https://reactome.org/PathwayBrowser/#/R-SSC-5603467 Activated protein C is released from PROCR IEA Sus scrofa 29108 R-SSC-5604929 https://reactome.org/PathwayBrowser/#/R-SSC-5604929 Activated protein C binds Protein S IEA Sus scrofa 29108 R-SSC-5606996 https://reactome.org/PathwayBrowser/#/R-SSC-5606996 Soluble PROCR binds activated protein C IEA Sus scrofa 29108 R-SSC-5607058 https://reactome.org/PathwayBrowser/#/R-SSC-5607058 Activated protein C:PROCR binds F2R IEA Sus scrofa 29108 R-SSC-5626316 https://reactome.org/PathwayBrowser/#/R-SSC-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Sus scrofa 29108 R-SSC-5626507 https://reactome.org/PathwayBrowser/#/R-SSC-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Sus scrofa 29108 R-SSC-5626549 https://reactome.org/PathwayBrowser/#/R-SSC-5626549 IQGAPs bind CALM1 IEA Sus scrofa 29108 R-SSC-5668629 https://reactome.org/PathwayBrowser/#/R-SSC-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Sus scrofa 29108 R-SSC-5672304 https://reactome.org/PathwayBrowser/#/R-SSC-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 IEA Sus scrofa 29108 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa 29108 R-SSC-5672969 https://reactome.org/PathwayBrowser/#/R-SSC-5672969 Phosphorylation of RAF IEA Sus scrofa 29108 R-SSC-5672972 https://reactome.org/PathwayBrowser/#/R-SSC-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Sus scrofa 29108 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 29108 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 29108 R-SSC-5672980 https://reactome.org/PathwayBrowser/#/R-SSC-5672980 Dissociation of RAS:RAF complex IEA Sus scrofa 29108 R-SSC-5694018 https://reactome.org/PathwayBrowser/#/R-SSC-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Sus scrofa 29108 R-SSC-5696131 https://reactome.org/PathwayBrowser/#/R-SSC-5696131 AOC1 deaminates Hist IEA Sus scrofa 29108 R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa 29108 R-SSC-622326 https://reactome.org/PathwayBrowser/#/R-SSC-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Sus scrofa 29108 R-SSC-629595 https://reactome.org/PathwayBrowser/#/R-SSC-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa 29108 R-SSC-6798474 https://reactome.org/PathwayBrowser/#/R-SSC-6798474 S100A8:S100A9 binds Zn2+ IEA Sus scrofa 29108 R-SSC-6798489 https://reactome.org/PathwayBrowser/#/R-SSC-6798489 S100A7 or S100A7A binds Zn2+ IEA Sus scrofa 29108 R-SSC-6798528 https://reactome.org/PathwayBrowser/#/R-SSC-6798528 S100A8:S100A9 binds Mn2+ IEA Sus scrofa 29108 R-SSC-6804527 https://reactome.org/PathwayBrowser/#/R-SSC-6804527 INTL1 binds bacterial glycans IEA Sus scrofa 29108 R-SSC-6805943 https://reactome.org/PathwayBrowser/#/R-SSC-6805943 S100A1 binds TLR4:LY96 IEA Sus scrofa 29108 R-SSC-71181 https://reactome.org/PathwayBrowser/#/R-SSC-71181 FAH cleaves 4FAA IEA Sus scrofa 29108 R-SSC-71401 https://reactome.org/PathwayBrowser/#/R-SSC-71401 OGDH dimer decarboxylates 2-OG IEA Sus scrofa 29108 R-SSC-71541 https://reactome.org/PathwayBrowser/#/R-SSC-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Sus scrofa 29108 R-SSC-71588 https://reactome.org/PathwayBrowser/#/R-SSC-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Sus scrofa 29108 R-SSC-74885 https://reactome.org/PathwayBrowser/#/R-SSC-74885 GUCYs converts GTP to cGMP IEA Sus scrofa 29108 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 29108 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 29108 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 29108 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 29108 R-SSC-74948 https://reactome.org/PathwayBrowser/#/R-SSC-74948 PP2A dephosphorylates p-RHO to RHO IEA Sus scrofa 29108 R-SSC-8848658 https://reactome.org/PathwayBrowser/#/R-SSC-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Sus scrofa 29108 R-SSC-8850846 https://reactome.org/PathwayBrowser/#/R-SSC-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Sus scrofa 29108 R-SSC-8850854 https://reactome.org/PathwayBrowser/#/R-SSC-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Sus scrofa 29108 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 29108 R-SSC-8851110 https://reactome.org/PathwayBrowser/#/R-SSC-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Sus scrofa 29108 R-SSC-8851129 https://reactome.org/PathwayBrowser/#/R-SSC-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Sus scrofa 29108 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 29108 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 29108 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 29108 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 29108 R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 29108 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 29108 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 29108 R-SSC-8852509 https://reactome.org/PathwayBrowser/#/R-SSC-8852509 CL-LK binds carbohydrates on target cell surface IEA Sus scrofa 29108 R-SSC-8852716 https://reactome.org/PathwayBrowser/#/R-SSC-8852716 Thrombin, ELANE cleave C5 IEA Sus scrofa 29108 R-SSC-8857662 https://reactome.org/PathwayBrowser/#/R-SSC-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Sus scrofa 29108 R-SSC-8862771 https://reactome.org/PathwayBrowser/#/R-SSC-8862771 PLA2G2A binds bacterial phospholipids IEA Sus scrofa 29108 R-SSC-8878787 https://reactome.org/PathwayBrowser/#/R-SSC-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Sus scrofa 29108 R-SSC-888589 https://reactome.org/PathwayBrowser/#/R-SSC-888589 Release of GABA at the synapse IEA Sus scrofa 29108 R-SSC-8932633 https://reactome.org/PathwayBrowser/#/R-SSC-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Sus scrofa 29108 R-SSC-8934446 https://reactome.org/PathwayBrowser/#/R-SSC-8934446 Activated PKC phosphorylates SHC1 IEA Sus scrofa 29108 R-SSC-8949178 https://reactome.org/PathwayBrowser/#/R-SSC-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Sus scrofa 29108 R-SSC-8949688 https://reactome.org/PathwayBrowser/#/R-SSC-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Sus scrofa 29108 R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 29108 R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 29108 R-SSC-9015379 https://reactome.org/PathwayBrowser/#/R-SSC-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Sus scrofa 29108 R-SSC-936883 https://reactome.org/PathwayBrowser/#/R-SSC-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Sus scrofa 29108 R-SSC-9603302 https://reactome.org/PathwayBrowser/#/R-SSC-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Sus scrofa 29108 R-SSC-9619355 https://reactome.org/PathwayBrowser/#/R-SSC-9619355 CaMKK autophosphorylates in the cytosol IEA Sus scrofa 29108 R-SSC-9619376 https://reactome.org/PathwayBrowser/#/R-SSC-9619376 CAMK1 binds calmodulin IEA Sus scrofa 29108 R-SSC-9626848 https://reactome.org/PathwayBrowser/#/R-SSC-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Sus scrofa 29108 R-SSC-9648983 https://reactome.org/PathwayBrowser/#/R-SSC-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Sus scrofa 29108 R-SSC-9653585 https://reactome.org/PathwayBrowser/#/R-SSC-9653585 S-Farn-Me KRAS4B binds calmodulin IEA Sus scrofa 29108 R-SSC-9654521 https://reactome.org/PathwayBrowser/#/R-SSC-9654521 Calmodulin dissociates KRAS4B from the plasma membrane IEA Sus scrofa 29108 R-SSC-9654523 https://reactome.org/PathwayBrowser/#/R-SSC-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Sus scrofa 29108 R-SSC-9654525 https://reactome.org/PathwayBrowser/#/R-SSC-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ IEA Sus scrofa 29108 R-SSC-9654533 https://reactome.org/PathwayBrowser/#/R-SSC-9654533 KRAS4B recycles to the plasma membrane IEA Sus scrofa 29108 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa 29108 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa 29108 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 29108 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa 29108 R-SSC-9659568 https://reactome.org/PathwayBrowser/#/R-SSC-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Sus scrofa 29108 R-SSC-9701055 https://reactome.org/PathwayBrowser/#/R-SSC-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Sus scrofa 29108 R-SSC-9701141 https://reactome.org/PathwayBrowser/#/R-SSC-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Sus scrofa 29108 R-SSC-9707186 https://reactome.org/PathwayBrowser/#/R-SSC-9707186 ALOX5 binds ALOX5 inhibitors IEA Sus scrofa 29108 R-SSC-9708859 https://reactome.org/PathwayBrowser/#/R-SSC-9708859 Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it IEA Sus scrofa 29108 R-SSC-9717215 https://reactome.org/PathwayBrowser/#/R-SSC-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Sus scrofa 29108 R-SSC-975311 https://reactome.org/PathwayBrowser/#/R-SSC-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Sus scrofa 29108 R-SSC-9756177 https://reactome.org/PathwayBrowser/#/R-SSC-9756177 PON1,3 hydrolyse ATVL to ATV IEA Sus scrofa 29108 R-SSC-9840949 https://reactome.org/PathwayBrowser/#/R-SSC-9840949 ARSA removes sulfate from SM3 IEA Sus scrofa 29108 R-SSC-9853499 https://reactome.org/PathwayBrowser/#/R-SSC-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 29108 R-SSC-9853512 https://reactome.org/PathwayBrowser/#/R-SSC-9853512 DLST transfers succinyl to CoA IEA Sus scrofa 29108 R-XLA-4332392 https://reactome.org/PathwayBrowser/#/R-XLA-4332392 translocation of Xenopus prkca to plasma membrane TAS Xenopus laevis 29108 R-XTR-111881 https://reactome.org/PathwayBrowser/#/R-XTR-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Xenopus tropicalis 29108 R-XTR-111883 https://reactome.org/PathwayBrowser/#/R-XTR-111883 Hydrolysis of phosphatidylcholine IEA Xenopus tropicalis 29108 R-XTR-111970 https://reactome.org/PathwayBrowser/#/R-XTR-111970 PKC phosphorylates GRK2 IEA Xenopus tropicalis 29108 R-XTR-114553 https://reactome.org/PathwayBrowser/#/R-XTR-114553 Activation of conventional Protein Kinase C IEA Xenopus tropicalis 29108 R-XTR-114683 https://reactome.org/PathwayBrowser/#/R-XTR-114683 Phosphorylation of Platelet Sec-1 IEA Xenopus tropicalis 29108 R-XTR-114684 https://reactome.org/PathwayBrowser/#/R-XTR-114684 Phosphorylation of Syntaxin-4 IEA Xenopus tropicalis 29108 R-XTR-114697 https://reactome.org/PathwayBrowser/#/R-XTR-114697 Activated thrombin (factor IIa) cleaves PAR3,4, activating them IEA Xenopus tropicalis 29108 R-XTR-1168373 https://reactome.org/PathwayBrowser/#/R-XTR-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Xenopus tropicalis 29108 R-XTR-1168376 https://reactome.org/PathwayBrowser/#/R-XTR-1168376 STIM1 oligomerizes IEA Xenopus tropicalis 29108 R-XTR-1168635 https://reactome.org/PathwayBrowser/#/R-XTR-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Xenopus tropicalis 29108 R-XTR-1183128 https://reactome.org/PathwayBrowser/#/R-XTR-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Xenopus tropicalis 29108 R-XTR-139854 https://reactome.org/PathwayBrowser/#/R-XTR-139854 IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol IEA Xenopus tropicalis 29108 R-XTR-139855 https://reactome.org/PathwayBrowser/#/R-XTR-139855 P2X1-mediated entry of Ca++ from plasma IEA Xenopus tropicalis 29108 R-XTR-139941 https://reactome.org/PathwayBrowser/#/R-XTR-139941 Binding of IP3 to IP3 receptor IEA Xenopus tropicalis 29108 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 29108 R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 29108 R-XTR-140769 https://reactome.org/PathwayBrowser/#/R-XTR-140769 factor VII -> factor VIIa IEA Xenopus tropicalis 29108 R-XTR-140791 https://reactome.org/PathwayBrowser/#/R-XTR-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Xenopus tropicalis 29108 R-XTR-140847 https://reactome.org/PathwayBrowser/#/R-XTR-140847 factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain IEA Xenopus tropicalis 29108 R-XTR-140870 https://reactome.org/PathwayBrowser/#/R-XTR-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Xenopus tropicalis 29108 R-XTR-140872 https://reactome.org/PathwayBrowser/#/R-XTR-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Xenopus tropicalis 29108 R-XTR-1482604 https://reactome.org/PathwayBrowser/#/R-XTR-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Xenopus tropicalis 29108 R-XTR-1482612 https://reactome.org/PathwayBrowser/#/R-XTR-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 29108 R-XTR-1482656 https://reactome.org/PathwayBrowser/#/R-XTR-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Xenopus tropicalis 29108 R-XTR-1482679 https://reactome.org/PathwayBrowser/#/R-XTR-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Xenopus tropicalis 29108 R-XTR-1482685 https://reactome.org/PathwayBrowser/#/R-XTR-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 29108 R-XTR-1482759 https://reactome.org/PathwayBrowser/#/R-XTR-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Xenopus tropicalis 29108 R-XTR-1482771 https://reactome.org/PathwayBrowser/#/R-XTR-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Xenopus tropicalis 29108 R-XTR-1482776 https://reactome.org/PathwayBrowser/#/R-XTR-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Xenopus tropicalis 29108 R-XTR-1482816 https://reactome.org/PathwayBrowser/#/R-XTR-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Xenopus tropicalis 29108 R-XTR-1482825 https://reactome.org/PathwayBrowser/#/R-XTR-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Xenopus tropicalis 29108 R-XTR-1482828 https://reactome.org/PathwayBrowser/#/R-XTR-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Xenopus tropicalis 29108 R-XTR-1482856 https://reactome.org/PathwayBrowser/#/R-XTR-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Xenopus tropicalis 29108 R-XTR-1482862 https://reactome.org/PathwayBrowser/#/R-XTR-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Xenopus tropicalis 29108 R-XTR-1482868 https://reactome.org/PathwayBrowser/#/R-XTR-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Xenopus tropicalis 29108 R-XTR-1482884 https://reactome.org/PathwayBrowser/#/R-XTR-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Xenopus tropicalis 29108 R-XTR-1482887 https://reactome.org/PathwayBrowser/#/R-XTR-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Xenopus tropicalis 29108 R-XTR-1482897 https://reactome.org/PathwayBrowser/#/R-XTR-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Xenopus tropicalis 29108 R-XTR-1482900 https://reactome.org/PathwayBrowser/#/R-XTR-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Xenopus tropicalis 29108 R-XTR-1482907 https://reactome.org/PathwayBrowser/#/R-XTR-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Xenopus tropicalis 29108 R-XTR-158333 https://reactome.org/PathwayBrowser/#/R-XTR-158333 factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) IEA Xenopus tropicalis 29108 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 29108 R-XTR-1602368 https://reactome.org/PathwayBrowser/#/R-XTR-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Xenopus tropicalis 29108 R-XTR-1602374 https://reactome.org/PathwayBrowser/#/R-XTR-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Xenopus tropicalis 29108 R-XTR-1602377 https://reactome.org/PathwayBrowser/#/R-XTR-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Xenopus tropicalis 29108 R-XTR-1602398 https://reactome.org/PathwayBrowser/#/R-XTR-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Xenopus tropicalis 29108 R-XTR-1602417 https://reactome.org/PathwayBrowser/#/R-XTR-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Xenopus tropicalis 29108 R-XTR-1602446 https://reactome.org/PathwayBrowser/#/R-XTR-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Xenopus tropicalis 29108 R-XTR-1606839 https://reactome.org/PathwayBrowser/#/R-XTR-1606839 ARSC hydrolyzes steroid sulfates IEA Xenopus tropicalis 29108 R-XTR-1614362 https://reactome.org/PathwayBrowser/#/R-XTR-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Xenopus tropicalis 29108 R-XTR-166726 https://reactome.org/PathwayBrowser/#/R-XTR-166726 Activation of MASPs IEA Xenopus tropicalis 29108 R-XTR-166753 https://reactome.org/PathwayBrowser/#/R-XTR-166753 Conversion of C4 into C4a and C4b IEA Xenopus tropicalis 29108 R-XTR-166792 https://reactome.org/PathwayBrowser/#/R-XTR-166792 Conversion of C2 into C2a and C2b IEA Xenopus tropicalis 29108 R-XTR-1675928 https://reactome.org/PathwayBrowser/#/R-XTR-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Xenopus tropicalis 29108 R-XTR-1675939 https://reactome.org/PathwayBrowser/#/R-XTR-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Xenopus tropicalis 29108 R-XTR-1675961 https://reactome.org/PathwayBrowser/#/R-XTR-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Xenopus tropicalis 29108 R-XTR-1676024 https://reactome.org/PathwayBrowser/#/R-XTR-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Xenopus tropicalis 29108 R-XTR-1676109 https://reactome.org/PathwayBrowser/#/R-XTR-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Xenopus tropicalis 29108 R-XTR-1676206 https://reactome.org/PathwayBrowser/#/R-XTR-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Xenopus tropicalis 29108 R-XTR-1678650 https://reactome.org/PathwayBrowser/#/R-XTR-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Xenopus tropicalis 29108 R-XTR-1793182 https://reactome.org/PathwayBrowser/#/R-XTR-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Xenopus tropicalis 29108 R-XTR-1855177 https://reactome.org/PathwayBrowser/#/R-XTR-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Xenopus tropicalis 29108 R-XTR-1855214 https://reactome.org/PathwayBrowser/#/R-XTR-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Xenopus tropicalis 29108 R-XTR-1855221 https://reactome.org/PathwayBrowser/#/R-XTR-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Xenopus tropicalis 29108 R-XTR-187020 https://reactome.org/PathwayBrowser/#/R-XTR-187020 Part of pro-beta-NGF is processed to mature beta-NGF IEA Xenopus tropicalis 29108 R-XTR-2089943 https://reactome.org/PathwayBrowser/#/R-XTR-2089943 TRPC1 translocates calcium from the extracellular region to the cytosol IEA Xenopus tropicalis 29108 R-XTR-2160892 https://reactome.org/PathwayBrowser/#/R-XTR-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Xenopus tropicalis 29108 R-XTR-2161768 https://reactome.org/PathwayBrowser/#/R-XTR-2161768 EXA4 is converted to EXC4 by LTC4S IEA Xenopus tropicalis 29108 R-XTR-2161907 https://reactome.org/PathwayBrowser/#/R-XTR-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Xenopus tropicalis 29108 R-XTR-2161917 https://reactome.org/PathwayBrowser/#/R-XTR-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Xenopus tropicalis 29108 R-XTR-2248891 https://reactome.org/PathwayBrowser/#/R-XTR-2248891 M6PR transports activated ARSA to the lysosome IEA Xenopus tropicalis 29108 R-XTR-2424243 https://reactome.org/PathwayBrowser/#/R-XTR-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Xenopus tropicalis 29108 R-XTR-2586748 https://reactome.org/PathwayBrowser/#/R-XTR-2586748 GUCA binds Ca2+ to form GUCA:Ca2+ IEA Xenopus tropicalis 29108 R-XTR-265153 https://reactome.org/PathwayBrowser/#/R-XTR-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule IEA Xenopus tropicalis 29108 R-XTR-265296 https://reactome.org/PathwayBrowser/#/R-XTR-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Xenopus tropicalis 29108 R-XTR-266050 https://reactome.org/PathwayBrowser/#/R-XTR-266050 LTA4 is converted to LTC4 by LTC4S IEA Xenopus tropicalis 29108 R-XTR-266051 https://reactome.org/PathwayBrowser/#/R-XTR-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Xenopus tropicalis 29108 R-XTR-2684901 https://reactome.org/PathwayBrowser/#/R-XTR-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Xenopus tropicalis 29108 R-XTR-2685505 https://reactome.org/PathwayBrowser/#/R-XTR-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Xenopus tropicalis 29108 R-XTR-2730867 https://reactome.org/PathwayBrowser/#/R-XTR-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Xenopus tropicalis 29108 R-XTR-2744242 https://reactome.org/PathwayBrowser/#/R-XTR-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Xenopus tropicalis 29108 R-XTR-2744361 https://reactome.org/PathwayBrowser/#/R-XTR-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Xenopus tropicalis 29108 R-XTR-2855054 https://reactome.org/PathwayBrowser/#/R-XTR-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Xenopus tropicalis 29108 R-XTR-2855125 https://reactome.org/PathwayBrowser/#/R-XTR-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Xenopus tropicalis 29108 R-XTR-3295579 https://reactome.org/PathwayBrowser/#/R-XTR-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Xenopus tropicalis 29108 R-XTR-354173 https://reactome.org/PathwayBrowser/#/R-XTR-354173 Activation of Rap1 by cytosolic GEFs IEA Xenopus tropicalis 29108 R-XTR-372448 https://reactome.org/PathwayBrowser/#/R-XTR-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Xenopus tropicalis 29108 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 29108 R-XTR-389463 https://reactome.org/PathwayBrowser/#/R-XTR-389463 Proteinase-activated receptors can bind thrombin IEA Xenopus tropicalis 29108 R-XTR-418309 https://reactome.org/PathwayBrowser/#/R-XTR-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Xenopus tropicalis 29108 R-XTR-418365 https://reactome.org/PathwayBrowser/#/R-XTR-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Xenopus tropicalis 29108 R-XTR-419001 https://reactome.org/PathwayBrowser/#/R-XTR-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Xenopus tropicalis 29108 R-XTR-420724 https://reactome.org/PathwayBrowser/#/R-XTR-420724 CASR binds Ca2+ IEA Xenopus tropicalis 29108 R-XTR-420739 https://reactome.org/PathwayBrowser/#/R-XTR-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Xenopus tropicalis 29108 R-XTR-425661 https://reactome.org/PathwayBrowser/#/R-XTR-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Xenopus tropicalis 29108 R-XTR-425678 https://reactome.org/PathwayBrowser/#/R-XTR-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Xenopus tropicalis 29108 R-XTR-426223 https://reactome.org/PathwayBrowser/#/R-XTR-426223 Cation influx mediated by TRPC3/6/7 IEA Xenopus tropicalis 29108 R-XTR-427910 https://reactome.org/PathwayBrowser/#/R-XTR-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Xenopus tropicalis 29108 R-XTR-428262 https://reactome.org/PathwayBrowser/#/R-XTR-428262 ACER3 hydrolyzes phytoceramide IEA Xenopus tropicalis 29108 R-XTR-429529 https://reactome.org/PathwayBrowser/#/R-XTR-429529 Thrombin binding to GP1b:IX:V IEA Xenopus tropicalis 29108 R-XTR-432164 https://reactome.org/PathwayBrowser/#/R-XTR-432164 Ca2+ influx into the post-synaptic cell IEA Xenopus tropicalis 29108 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 29108 R-XTR-5138432 https://reactome.org/PathwayBrowser/#/R-XTR-5138432 DVL2 is phosphorylated by PKC IEA Xenopus tropicalis 29108 R-XTR-5218813 https://reactome.org/PathwayBrowser/#/R-XTR-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Xenopus tropicalis 29108 R-XTR-5223304 https://reactome.org/PathwayBrowser/#/R-XTR-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Xenopus tropicalis 29108 R-XTR-5229194 https://reactome.org/PathwayBrowser/#/R-XTR-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Xenopus tropicalis 29108 R-XTR-5333671 https://reactome.org/PathwayBrowser/#/R-XTR-5333671 CLCAs self cleave IEA Xenopus tropicalis 29108 R-XTR-5333678 https://reactome.org/PathwayBrowser/#/R-XTR-5333678 CPNEs bind PL IEA Xenopus tropicalis 29108 R-XTR-5577213 https://reactome.org/PathwayBrowser/#/R-XTR-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Xenopus tropicalis 29108 R-XTR-5578883 https://reactome.org/PathwayBrowser/#/R-XTR-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Xenopus tropicalis 29108 R-XTR-5591086 https://reactome.org/PathwayBrowser/#/R-XTR-5591086 SERPINA5 binds activated protein C IEA Xenopus tropicalis 29108 R-XTR-5602080 https://reactome.org/PathwayBrowser/#/R-XTR-5602080 Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. IEA Xenopus tropicalis 29108 R-XTR-5604929 https://reactome.org/PathwayBrowser/#/R-XTR-5604929 Activated protein C binds Protein S IEA Xenopus tropicalis 29108 R-XTR-5626316 https://reactome.org/PathwayBrowser/#/R-XTR-5626316 SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ IEA Xenopus tropicalis 29108 R-XTR-5668629 https://reactome.org/PathwayBrowser/#/R-XTR-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Xenopus tropicalis 29108 R-XTR-5694018 https://reactome.org/PathwayBrowser/#/R-XTR-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Xenopus tropicalis 29108 R-XTR-5696131 https://reactome.org/PathwayBrowser/#/R-XTR-5696131 AOC1 deaminates Hist IEA Xenopus tropicalis 29108 R-XTR-5696183 https://reactome.org/PathwayBrowser/#/R-XTR-5696183 AOC3 deaminates BZAM IEA Xenopus tropicalis 29108 R-XTR-622326 https://reactome.org/PathwayBrowser/#/R-XTR-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Xenopus tropicalis 29108 R-XTR-629595 https://reactome.org/PathwayBrowser/#/R-XTR-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 29108 R-XTR-6798474 https://reactome.org/PathwayBrowser/#/R-XTR-6798474 S100A8:S100A9 binds Zn2+ IEA Xenopus tropicalis 29108 R-XTR-6798489 https://reactome.org/PathwayBrowser/#/R-XTR-6798489 S100A7 or S100A7A binds Zn2+ IEA Xenopus tropicalis 29108 R-XTR-6798528 https://reactome.org/PathwayBrowser/#/R-XTR-6798528 S100A8:S100A9 binds Mn2+ IEA Xenopus tropicalis 29108 R-XTR-6804527 https://reactome.org/PathwayBrowser/#/R-XTR-6804527 INTL1 binds bacterial glycans IEA Xenopus tropicalis 29108 R-XTR-71181 https://reactome.org/PathwayBrowser/#/R-XTR-71181 FAH cleaves 4FAA IEA Xenopus tropicalis 29108 R-XTR-71401 https://reactome.org/PathwayBrowser/#/R-XTR-71401 OGDH dimer decarboxylates 2-OG IEA Xenopus tropicalis 29108 R-XTR-71588 https://reactome.org/PathwayBrowser/#/R-XTR-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Xenopus tropicalis 29108 R-XTR-74885 https://reactome.org/PathwayBrowser/#/R-XTR-74885 GUCYs converts GTP to cGMP IEA Xenopus tropicalis 29108 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 29108 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 29108 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 29108 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 29108 R-XTR-8848658 https://reactome.org/PathwayBrowser/#/R-XTR-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Xenopus tropicalis 29108 R-XTR-8850846 https://reactome.org/PathwayBrowser/#/R-XTR-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 29108 R-XTR-8850854 https://reactome.org/PathwayBrowser/#/R-XTR-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 29108 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 29108 R-XTR-8851110 https://reactome.org/PathwayBrowser/#/R-XTR-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 29108 R-XTR-8851129 https://reactome.org/PathwayBrowser/#/R-XTR-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 29108 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 29108 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 29108 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 29108 R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 29108 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 29108 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 29108 R-XTR-8862771 https://reactome.org/PathwayBrowser/#/R-XTR-8862771 PLA2G2A binds bacterial phospholipids IEA Xenopus tropicalis 29108 R-XTR-8878787 https://reactome.org/PathwayBrowser/#/R-XTR-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Xenopus tropicalis 29108 R-XTR-8932633 https://reactome.org/PathwayBrowser/#/R-XTR-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Xenopus tropicalis 29108 R-XTR-8949178 https://reactome.org/PathwayBrowser/#/R-XTR-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Xenopus tropicalis 29108 R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 29108 R-XTR-9015379 https://reactome.org/PathwayBrowser/#/R-XTR-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Xenopus tropicalis 29108 R-XTR-936883 https://reactome.org/PathwayBrowser/#/R-XTR-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Xenopus tropicalis 29108 R-XTR-9603302 https://reactome.org/PathwayBrowser/#/R-XTR-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Xenopus tropicalis 29108 R-XTR-9626848 https://reactome.org/PathwayBrowser/#/R-XTR-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Xenopus tropicalis 29108 R-XTR-9659568 https://reactome.org/PathwayBrowser/#/R-XTR-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Xenopus tropicalis 29108 R-XTR-9701141 https://reactome.org/PathwayBrowser/#/R-XTR-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Xenopus tropicalis 29108 R-XTR-9707186 https://reactome.org/PathwayBrowser/#/R-XTR-9707186 ALOX5 binds ALOX5 inhibitors IEA Xenopus tropicalis 29108 R-XTR-9708859 https://reactome.org/PathwayBrowser/#/R-XTR-9708859 Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it IEA Xenopus tropicalis 29108 R-XTR-9717215 https://reactome.org/PathwayBrowser/#/R-XTR-9717215 ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol IEA Xenopus tropicalis 29108 R-XTR-9756177 https://reactome.org/PathwayBrowser/#/R-XTR-9756177 PON1,3 hydrolyse ATVL to ATV IEA Xenopus tropicalis 29108 R-XTR-9840949 https://reactome.org/PathwayBrowser/#/R-XTR-9840949 ARSA removes sulfate from SM3 IEA Xenopus tropicalis 29108 R-XTR-9853499 https://reactome.org/PathwayBrowser/#/R-XTR-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 29108 R-XTR-9853512 https://reactome.org/PathwayBrowser/#/R-XTR-9853512 DLST transfers succinyl to CoA IEA Xenopus tropicalis 29115 R-BTA-5649681 https://reactome.org/PathwayBrowser/#/R-BTA-5649681 NEIL2 cleaves 5-OHU from damaged DNA IEA Bos taurus 29115 R-CFA-110217 https://reactome.org/PathwayBrowser/#/R-CFA-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase IEA Canis familiaris 29115 R-CFA-5649681 https://reactome.org/PathwayBrowser/#/R-CFA-5649681 NEIL2 cleaves 5-OHU from damaged DNA IEA Canis familiaris 29115 R-DDI-110217 https://reactome.org/PathwayBrowser/#/R-DDI-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase IEA Dictyostelium discoideum 29115 R-DRE-110217 https://reactome.org/PathwayBrowser/#/R-DRE-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase IEA Danio rerio 29115 R-GGA-110217 https://reactome.org/PathwayBrowser/#/R-GGA-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase IEA Gallus gallus 29115 R-GGA-5649681 https://reactome.org/PathwayBrowser/#/R-GGA-5649681 NEIL2 cleaves 5-OHU from damaged DNA IEA Gallus gallus 29115 R-HSA-110217 https://reactome.org/PathwayBrowser/#/R-HSA-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase TAS Homo sapiens 29115 R-HSA-5649681 https://reactome.org/PathwayBrowser/#/R-HSA-5649681 NEIL2 cleaves 5-OHU from damaged DNA TAS Homo sapiens 29115 R-MMU-110217 https://reactome.org/PathwayBrowser/#/R-MMU-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase IEA Mus musculus 29115 R-MMU-5649681 https://reactome.org/PathwayBrowser/#/R-MMU-5649681 NEIL2 cleaves 5-OHU from damaged DNA IEA Mus musculus 29115 R-PFA-110217 https://reactome.org/PathwayBrowser/#/R-PFA-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase IEA Plasmodium falciparum 29115 R-RNO-110217 https://reactome.org/PathwayBrowser/#/R-RNO-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase IEA Rattus norvegicus 29115 R-RNO-5649681 https://reactome.org/PathwayBrowser/#/R-RNO-5649681 NEIL2 cleaves 5-OHU from damaged DNA IEA Rattus norvegicus 29115 R-SCE-110217 https://reactome.org/PathwayBrowser/#/R-SCE-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase IEA Saccharomyces cerevisiae 29115 R-SPO-110217 https://reactome.org/PathwayBrowser/#/R-SPO-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase IEA Schizosaccharomyces pombe 29115 R-SSC-110217 https://reactome.org/PathwayBrowser/#/R-SSC-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase IEA Sus scrofa 29115 R-SSC-5649681 https://reactome.org/PathwayBrowser/#/R-SSC-5649681 NEIL2 cleaves 5-OHU from damaged DNA IEA Sus scrofa 29115 R-XTR-110217 https://reactome.org/PathwayBrowser/#/R-XTR-110217 Cleavage of 5-hydroxyluracil by UNG glycosylase IEA Xenopus tropicalis 29115 R-XTR-5649681 https://reactome.org/PathwayBrowser/#/R-XTR-5649681 NEIL2 cleaves 5-OHU from damaged DNA IEA Xenopus tropicalis 29117 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 29117 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 29117 R-BTA-5625717 https://reactome.org/PathwayBrowser/#/R-BTA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Bos taurus 29117 R-BTA-5625738 https://reactome.org/PathwayBrowser/#/R-BTA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Bos taurus 29117 R-BTA-5625745 https://reactome.org/PathwayBrowser/#/R-BTA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Bos taurus 29117 R-BTA-5625774 https://reactome.org/PathwayBrowser/#/R-BTA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Bos taurus 29117 R-BTA-5625784 https://reactome.org/PathwayBrowser/#/R-BTA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Bos taurus 29117 R-BTA-5625796 https://reactome.org/PathwayBrowser/#/R-BTA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Bos taurus 29117 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 29117 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 29117 R-BTA-5625849 https://reactome.org/PathwayBrowser/#/R-BTA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Bos taurus 29117 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 29117 R-BTA-8877902 https://reactome.org/PathwayBrowser/#/R-BTA-8877902 Activated AR binds RUNX2 IEA Bos taurus 29117 R-BTA-9705925 https://reactome.org/PathwayBrowser/#/R-BTA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Bos taurus 29117 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 29117 R-CFA-5625717 https://reactome.org/PathwayBrowser/#/R-CFA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Canis familiaris 29117 R-CFA-5625738 https://reactome.org/PathwayBrowser/#/R-CFA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Canis familiaris 29117 R-CFA-5625745 https://reactome.org/PathwayBrowser/#/R-CFA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Canis familiaris 29117 R-CFA-5625774 https://reactome.org/PathwayBrowser/#/R-CFA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Canis familiaris 29117 R-CFA-5625784 https://reactome.org/PathwayBrowser/#/R-CFA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Canis familiaris 29117 R-CFA-5625796 https://reactome.org/PathwayBrowser/#/R-CFA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Canis familiaris 29117 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 29117 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 29117 R-CFA-5625849 https://reactome.org/PathwayBrowser/#/R-CFA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Canis familiaris 29117 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 29117 R-CFA-8877902 https://reactome.org/PathwayBrowser/#/R-CFA-8877902 Activated AR binds RUNX2 IEA Canis familiaris 29117 R-CFA-9705925 https://reactome.org/PathwayBrowser/#/R-CFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Canis familiaris 29117 R-DDI-5625784 https://reactome.org/PathwayBrowser/#/R-DDI-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Dictyostelium discoideum 29117 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 29117 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 29117 R-DME-5625717 https://reactome.org/PathwayBrowser/#/R-DME-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Drosophila melanogaster 29117 R-DME-5625738 https://reactome.org/PathwayBrowser/#/R-DME-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Drosophila melanogaster 29117 R-DME-5625745 https://reactome.org/PathwayBrowser/#/R-DME-5625745 PKN1 stimulates association of AR with NCOA2 IEA Drosophila melanogaster 29117 R-DME-5625774 https://reactome.org/PathwayBrowser/#/R-DME-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Drosophila melanogaster 29117 R-DME-5625784 https://reactome.org/PathwayBrowser/#/R-DME-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Drosophila melanogaster 29117 R-DME-5625796 https://reactome.org/PathwayBrowser/#/R-DME-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 29117 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 29117 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 29117 R-DME-5625849 https://reactome.org/PathwayBrowser/#/R-DME-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 29117 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 29117 R-DME-8877902 https://reactome.org/PathwayBrowser/#/R-DME-8877902 Activated AR binds RUNX2 IEA Drosophila melanogaster 29117 R-DME-9705925 https://reactome.org/PathwayBrowser/#/R-DME-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Drosophila melanogaster 29117 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 29117 R-DRE-5625717 https://reactome.org/PathwayBrowser/#/R-DRE-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Danio rerio 29117 R-DRE-5625738 https://reactome.org/PathwayBrowser/#/R-DRE-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Danio rerio 29117 R-DRE-5625745 https://reactome.org/PathwayBrowser/#/R-DRE-5625745 PKN1 stimulates association of AR with NCOA2 IEA Danio rerio 29117 R-DRE-5625774 https://reactome.org/PathwayBrowser/#/R-DRE-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Danio rerio 29117 R-DRE-5625784 https://reactome.org/PathwayBrowser/#/R-DRE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Danio rerio 29117 R-DRE-5625796 https://reactome.org/PathwayBrowser/#/R-DRE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Danio rerio 29117 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 29117 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 29117 R-DRE-8877902 https://reactome.org/PathwayBrowser/#/R-DRE-8877902 Activated AR binds RUNX2 IEA Danio rerio 29117 R-DRE-9705925 https://reactome.org/PathwayBrowser/#/R-DRE-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Danio rerio 29117 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 29117 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 29117 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus 29117 R-GGA-5625796 https://reactome.org/PathwayBrowser/#/R-GGA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Gallus gallus 29117 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 29117 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 29117 R-GGA-5625849 https://reactome.org/PathwayBrowser/#/R-GGA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Gallus gallus 29117 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 29117 R-GGA-8877902 https://reactome.org/PathwayBrowser/#/R-GGA-8877902 Activated AR binds RUNX2 IEA Gallus gallus 29117 R-GGA-9705925 https://reactome.org/PathwayBrowser/#/R-GGA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Gallus gallus 29117 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 29117 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 29117 R-HSA-5625717 https://reactome.org/PathwayBrowser/#/R-HSA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) TAS Homo sapiens 29117 R-HSA-5625738 https://reactome.org/PathwayBrowser/#/R-HSA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus TAS Homo sapiens 29117 R-HSA-5625745 https://reactome.org/PathwayBrowser/#/R-HSA-5625745 PKN1 stimulates association of AR with NCOA2 TAS Homo sapiens 29117 R-HSA-5625774 https://reactome.org/PathwayBrowser/#/R-HSA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes TAS Homo sapiens 29117 R-HSA-5625784 https://reactome.org/PathwayBrowser/#/R-HSA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters TAS Homo sapiens 29117 R-HSA-5625796 https://reactome.org/PathwayBrowser/#/R-HSA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters TAS Homo sapiens 29117 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 29117 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 29117 R-HSA-5625849 https://reactome.org/PathwayBrowser/#/R-HSA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters TAS Homo sapiens 29117 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 29117 R-HSA-5625883 https://reactome.org/PathwayBrowser/#/R-HSA-5625883 PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 TAS Homo sapiens 29117 R-HSA-8877902 https://reactome.org/PathwayBrowser/#/R-HSA-8877902 Activated AR binds RUNX2 TAS Homo sapiens 29117 R-HSA-8877918 https://reactome.org/PathwayBrowser/#/R-HSA-8877918 RUNX2:MAF complex binds the BGLAP gene promoter IEA Homo sapiens 29117 R-HSA-9705925 https://reactome.org/PathwayBrowser/#/R-HSA-9705925 Androgens binds AR (in the HSP90 chaperone complex) TAS Homo sapiens 29117 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 29117 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 29117 R-MMU-5625717 https://reactome.org/PathwayBrowser/#/R-MMU-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Mus musculus 29117 R-MMU-5625738 https://reactome.org/PathwayBrowser/#/R-MMU-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Mus musculus 29117 R-MMU-5625745 https://reactome.org/PathwayBrowser/#/R-MMU-5625745 PKN1 stimulates association of AR with NCOA2 IEA Mus musculus 29117 R-MMU-8877902 https://reactome.org/PathwayBrowser/#/R-MMU-8877902 Activated AR binds RUNX2 IEA Mus musculus 29117 R-MMU-9705925 https://reactome.org/PathwayBrowser/#/R-MMU-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Mus musculus 29117 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 29117 R-PFA-9705925 https://reactome.org/PathwayBrowser/#/R-PFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Plasmodium falciparum 29117 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 29117 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 29117 R-RNO-5625717 https://reactome.org/PathwayBrowser/#/R-RNO-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Rattus norvegicus 29117 R-RNO-5625738 https://reactome.org/PathwayBrowser/#/R-RNO-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Rattus norvegicus 29117 R-RNO-5625745 https://reactome.org/PathwayBrowser/#/R-RNO-5625745 PKN1 stimulates association of AR with NCOA2 IEA Rattus norvegicus 29117 R-RNO-5625774 https://reactome.org/PathwayBrowser/#/R-RNO-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Rattus norvegicus 29117 R-RNO-5625784 https://reactome.org/PathwayBrowser/#/R-RNO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Rattus norvegicus 29117 R-RNO-5625796 https://reactome.org/PathwayBrowser/#/R-RNO-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Rattus norvegicus 29117 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 29117 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 29117 R-RNO-5625849 https://reactome.org/PathwayBrowser/#/R-RNO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Rattus norvegicus 29117 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 29117 R-RNO-9705925 https://reactome.org/PathwayBrowser/#/R-RNO-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Rattus norvegicus 29117 R-SCE-5625784 https://reactome.org/PathwayBrowser/#/R-SCE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 29117 R-SCE-5625796 https://reactome.org/PathwayBrowser/#/R-SCE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 29117 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 29117 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 29117 R-SCE-5625849 https://reactome.org/PathwayBrowser/#/R-SCE-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 29117 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 29117 R-SPO-5625784 https://reactome.org/PathwayBrowser/#/R-SPO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 29117 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 29117 R-SPO-5625849 https://reactome.org/PathwayBrowser/#/R-SPO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 29117 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 29117 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 29117 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 29117 R-SSC-5625717 https://reactome.org/PathwayBrowser/#/R-SSC-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Sus scrofa 29117 R-SSC-5625738 https://reactome.org/PathwayBrowser/#/R-SSC-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Sus scrofa 29117 R-SSC-5625745 https://reactome.org/PathwayBrowser/#/R-SSC-5625745 PKN1 stimulates association of AR with NCOA2 IEA Sus scrofa 29117 R-SSC-5625774 https://reactome.org/PathwayBrowser/#/R-SSC-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Sus scrofa 29117 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa 29117 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa 29117 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 29117 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 29117 R-SSC-5625849 https://reactome.org/PathwayBrowser/#/R-SSC-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Sus scrofa 29117 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 29117 R-SSC-8877902 https://reactome.org/PathwayBrowser/#/R-SSC-8877902 Activated AR binds RUNX2 IEA Sus scrofa 29117 R-SSC-9705925 https://reactome.org/PathwayBrowser/#/R-SSC-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Sus scrofa 29117 R-XTR-8877902 https://reactome.org/PathwayBrowser/#/R-XTR-8877902 Activated AR binds RUNX2 IEA Xenopus tropicalis 29117 R-XTR-9705925 https://reactome.org/PathwayBrowser/#/R-XTR-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Xenopus tropicalis 29119 R-BTA-109341 https://reactome.org/PathwayBrowser/#/R-BTA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Bos taurus 29119 R-BTA-109343 https://reactome.org/PathwayBrowser/#/R-BTA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Bos taurus 29119 R-CEL-109341 https://reactome.org/PathwayBrowser/#/R-CEL-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Caenorhabditis elegans 29119 R-CEL-109343 https://reactome.org/PathwayBrowser/#/R-CEL-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Caenorhabditis elegans 29119 R-CFA-109341 https://reactome.org/PathwayBrowser/#/R-CFA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Canis familiaris 29119 R-CFA-109343 https://reactome.org/PathwayBrowser/#/R-CFA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Canis familiaris 29119 R-DME-109341 https://reactome.org/PathwayBrowser/#/R-DME-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Drosophila melanogaster 29119 R-GGA-109341 https://reactome.org/PathwayBrowser/#/R-GGA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Gallus gallus 29119 R-GGA-109343 https://reactome.org/PathwayBrowser/#/R-GGA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Gallus gallus 29119 R-HSA-109341 https://reactome.org/PathwayBrowser/#/R-HSA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA TAS Homo sapiens 29119 R-HSA-109343 https://reactome.org/PathwayBrowser/#/R-HSA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA TAS Homo sapiens 29119 R-MMU-109341 https://reactome.org/PathwayBrowser/#/R-MMU-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Mus musculus 29119 R-MMU-109343 https://reactome.org/PathwayBrowser/#/R-MMU-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Mus musculus 29119 R-RNO-109341 https://reactome.org/PathwayBrowser/#/R-RNO-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Rattus norvegicus 29119 R-RNO-109343 https://reactome.org/PathwayBrowser/#/R-RNO-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Rattus norvegicus 29119 R-SSC-109341 https://reactome.org/PathwayBrowser/#/R-SSC-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Sus scrofa 29119 R-SSC-109343 https://reactome.org/PathwayBrowser/#/R-SSC-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Sus scrofa 29119 R-XTR-109343 https://reactome.org/PathwayBrowser/#/R-XTR-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Xenopus tropicalis 29120 R-HSA-1222384 https://reactome.org/PathwayBrowser/#/R-HSA-1222384 Glutathione scavenges nitrosyl TAS Homo sapiens 29120 R-HSA-1222512 https://reactome.org/PathwayBrowser/#/R-HSA-1222512 Nitric oxide oxidizes to nitrosyl ion TAS Homo sapiens 29120 R-HSA-1222594 https://reactome.org/PathwayBrowser/#/R-HSA-1222594 Mycothiol scavenges nitrosyl TAS Homo sapiens 29120 R-HSA-1222723 https://reactome.org/PathwayBrowser/#/R-HSA-1222723 Nitric oxide is oxidized to nitrate TAS Homo sapiens 29126 R-BTA-109343 https://reactome.org/PathwayBrowser/#/R-BTA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Bos taurus 29126 R-BTA-109998 https://reactome.org/PathwayBrowser/#/R-BTA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Bos taurus 29126 R-CEL-109343 https://reactome.org/PathwayBrowser/#/R-CEL-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Caenorhabditis elegans 29126 R-CFA-109343 https://reactome.org/PathwayBrowser/#/R-CFA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Canis familiaris 29126 R-CFA-109998 https://reactome.org/PathwayBrowser/#/R-CFA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Canis familiaris 29126 R-DME-109998 https://reactome.org/PathwayBrowser/#/R-DME-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Drosophila melanogaster 29126 R-GGA-109343 https://reactome.org/PathwayBrowser/#/R-GGA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Gallus gallus 29126 R-GGA-109998 https://reactome.org/PathwayBrowser/#/R-GGA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Gallus gallus 29126 R-HSA-109343 https://reactome.org/PathwayBrowser/#/R-HSA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA TAS Homo sapiens 29126 R-HSA-109998 https://reactome.org/PathwayBrowser/#/R-HSA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA TAS Homo sapiens 29126 R-MMU-109343 https://reactome.org/PathwayBrowser/#/R-MMU-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Mus musculus 29126 R-MMU-109998 https://reactome.org/PathwayBrowser/#/R-MMU-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Mus musculus 29126 R-RNO-109343 https://reactome.org/PathwayBrowser/#/R-RNO-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Rattus norvegicus 29126 R-RNO-109998 https://reactome.org/PathwayBrowser/#/R-RNO-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Rattus norvegicus 29126 R-SSC-109343 https://reactome.org/PathwayBrowser/#/R-SSC-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Sus scrofa 29126 R-SSC-109998 https://reactome.org/PathwayBrowser/#/R-SSC-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Sus scrofa 29126 R-XTR-109343 https://reactome.org/PathwayBrowser/#/R-XTR-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Xenopus tropicalis 29126 R-XTR-109998 https://reactome.org/PathwayBrowser/#/R-XTR-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Xenopus tropicalis 29127 R-BTA-110226 https://reactome.org/PathwayBrowser/#/R-BTA-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Bos taurus 29127 R-CEL-110226 https://reactome.org/PathwayBrowser/#/R-CEL-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Caenorhabditis elegans 29127 R-CFA-110226 https://reactome.org/PathwayBrowser/#/R-CFA-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Canis familiaris 29127 R-DDI-110226 https://reactome.org/PathwayBrowser/#/R-DDI-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Dictyostelium discoideum 29127 R-DME-110226 https://reactome.org/PathwayBrowser/#/R-DME-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Drosophila melanogaster 29127 R-GGA-110226 https://reactome.org/PathwayBrowser/#/R-GGA-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Gallus gallus 29127 R-HSA-110226 https://reactome.org/PathwayBrowser/#/R-HSA-110226 Cleavage of cytosine glycol by NTHL1 glycosylase TAS Homo sapiens 29127 R-MMU-110226 https://reactome.org/PathwayBrowser/#/R-MMU-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Mus musculus 29127 R-PFA-110226 https://reactome.org/PathwayBrowser/#/R-PFA-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Plasmodium falciparum 29127 R-RNO-110226 https://reactome.org/PathwayBrowser/#/R-RNO-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Rattus norvegicus 29127 R-SCE-110226 https://reactome.org/PathwayBrowser/#/R-SCE-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Saccharomyces cerevisiae 29127 R-SPO-110226 https://reactome.org/PathwayBrowser/#/R-SPO-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Schizosaccharomyces pombe 29127 R-SSC-110226 https://reactome.org/PathwayBrowser/#/R-SSC-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Sus scrofa 29127 R-XTR-110226 https://reactome.org/PathwayBrowser/#/R-XTR-110226 Cleavage of cytosine glycol by NTHL1 glycosylase IEA Xenopus tropicalis 29128 R-BTA-110224 https://reactome.org/PathwayBrowser/#/R-BTA-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Bos taurus 29128 R-BTA-9629149 https://reactome.org/PathwayBrowser/#/R-BTA-9629149 NEIL1 cleaves thymine glycol from damaged DNA IEA Bos taurus 29128 R-CEL-110224 https://reactome.org/PathwayBrowser/#/R-CEL-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Caenorhabditis elegans 29128 R-CFA-110224 https://reactome.org/PathwayBrowser/#/R-CFA-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Canis familiaris 29128 R-CFA-9629149 https://reactome.org/PathwayBrowser/#/R-CFA-9629149 NEIL1 cleaves thymine glycol from damaged DNA IEA Canis familiaris 29128 R-DDI-110224 https://reactome.org/PathwayBrowser/#/R-DDI-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Dictyostelium discoideum 29128 R-DME-110224 https://reactome.org/PathwayBrowser/#/R-DME-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Drosophila melanogaster 29128 R-DRE-9629149 https://reactome.org/PathwayBrowser/#/R-DRE-9629149 NEIL1 cleaves thymine glycol from damaged DNA IEA Danio rerio 29128 R-GGA-110224 https://reactome.org/PathwayBrowser/#/R-GGA-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Gallus gallus 29128 R-GGA-9629149 https://reactome.org/PathwayBrowser/#/R-GGA-9629149 NEIL1 cleaves thymine glycol from damaged DNA IEA Gallus gallus 29128 R-HSA-110224 https://reactome.org/PathwayBrowser/#/R-HSA-110224 Cleavage of thymine glycol by NTHL1 glycosylase TAS Homo sapiens 29128 R-HSA-9629149 https://reactome.org/PathwayBrowser/#/R-HSA-9629149 NEIL1 cleaves thymine glycol from damaged DNA TAS Homo sapiens 29128 R-HSA-9629497 https://reactome.org/PathwayBrowser/#/R-HSA-9629497 NEIL3 cleaves thymine glycol from telomeric DNA IEA Homo sapiens 29128 R-HSA-9629499 https://reactome.org/PathwayBrowser/#/R-HSA-9629499 NEIL3 cleaves thymine glycol IEA Homo sapiens 29128 R-MMU-110224 https://reactome.org/PathwayBrowser/#/R-MMU-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Mus musculus 29128 R-MMU-9629149 https://reactome.org/PathwayBrowser/#/R-MMU-9629149 NEIL1 cleaves thymine glycol from damaged DNA IEA Mus musculus 29128 R-MMU-9629509 https://reactome.org/PathwayBrowser/#/R-MMU-9629509 Neil3 cleaves thymine glycol TAS Mus musculus 29128 R-MMU-9629510 https://reactome.org/PathwayBrowser/#/R-MMU-9629510 Neil3 cleaves thymine glycol from telomeric DNA oligomer TAS Mus musculus 29128 R-PFA-110224 https://reactome.org/PathwayBrowser/#/R-PFA-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Plasmodium falciparum 29128 R-RNO-110224 https://reactome.org/PathwayBrowser/#/R-RNO-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Rattus norvegicus 29128 R-RNO-9629149 https://reactome.org/PathwayBrowser/#/R-RNO-9629149 NEIL1 cleaves thymine glycol from damaged DNA IEA Rattus norvegicus 29128 R-SCE-110224 https://reactome.org/PathwayBrowser/#/R-SCE-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Saccharomyces cerevisiae 29128 R-SPO-110224 https://reactome.org/PathwayBrowser/#/R-SPO-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Schizosaccharomyces pombe 29128 R-SSC-110224 https://reactome.org/PathwayBrowser/#/R-SSC-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Sus scrofa 29128 R-SSC-9629149 https://reactome.org/PathwayBrowser/#/R-SSC-9629149 NEIL1 cleaves thymine glycol from damaged DNA IEA Sus scrofa 29128 R-XTR-110224 https://reactome.org/PathwayBrowser/#/R-XTR-110224 Cleavage of thymine glycol by NTHL1 glycosylase IEA Xenopus tropicalis 29128 R-XTR-9629149 https://reactome.org/PathwayBrowser/#/R-XTR-9629149 NEIL1 cleaves thymine glycol from damaged DNA IEA Xenopus tropicalis 29129 R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 29129 R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 29129 R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 29129 R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 29129 R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 29129 R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 29129 R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 29129 R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 29129 R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 29129 R-RNO-76354 https://reactome.org/PathwayBrowser/#/R-RNO-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Rattus norvegicus 29129 R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa 29129 R-XTR-76354 https://reactome.org/PathwayBrowser/#/R-XTR-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Xenopus tropicalis 29132 R-BTA-176054 https://reactome.org/PathwayBrowser/#/R-BTA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Bos taurus 29132 R-BTA-176059 https://reactome.org/PathwayBrowser/#/R-BTA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Bos taurus 29132 R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 29132 R-CEL-176054 https://reactome.org/PathwayBrowser/#/R-CEL-176054 GST dimers conjugate GSH with cytosolic substrates IEA Caenorhabditis elegans 29132 R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 29132 R-CFA-176054 https://reactome.org/PathwayBrowser/#/R-CFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Canis familiaris 29132 R-CFA-176059 https://reactome.org/PathwayBrowser/#/R-CFA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Canis familiaris 29132 R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 29132 R-DDI-176054 https://reactome.org/PathwayBrowser/#/R-DDI-176054 GST dimers conjugate GSH with cytosolic substrates IEA Dictyostelium discoideum 29132 R-DDI-176059 https://reactome.org/PathwayBrowser/#/R-DDI-176059 GST trimers transfer GS from GSH to luminal substrates IEA Dictyostelium discoideum 29132 R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 29132 R-DME-176054 https://reactome.org/PathwayBrowser/#/R-DME-176054 GST dimers conjugate GSH with cytosolic substrates IEA Drosophila melanogaster 29132 R-DME-176059 https://reactome.org/PathwayBrowser/#/R-DME-176059 GST trimers transfer GS from GSH to luminal substrates IEA Drosophila melanogaster 29132 R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 29132 R-DRE-176054 https://reactome.org/PathwayBrowser/#/R-DRE-176054 GST dimers conjugate GSH with cytosolic substrates IEA Danio rerio 29132 R-DRE-176059 https://reactome.org/PathwayBrowser/#/R-DRE-176059 GST trimers transfer GS from GSH to luminal substrates IEA Danio rerio 29132 R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 29132 R-GGA-176054 https://reactome.org/PathwayBrowser/#/R-GGA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Gallus gallus 29132 R-GGA-176059 https://reactome.org/PathwayBrowser/#/R-GGA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Gallus gallus 29132 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 29132 R-HSA-176054 https://reactome.org/PathwayBrowser/#/R-HSA-176054 GST dimers conjugate GSH with cytosolic substrates TAS Homo sapiens 29132 R-HSA-176059 https://reactome.org/PathwayBrowser/#/R-HSA-176059 GST trimers transfer GS from GSH to luminal substrates TAS Homo sapiens 29132 R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 29132 R-MMU-176054 https://reactome.org/PathwayBrowser/#/R-MMU-176054 GST dimers conjugate GSH with cytosolic substrates IEA Mus musculus 29132 R-MMU-176059 https://reactome.org/PathwayBrowser/#/R-MMU-176059 GST trimers transfer GS from GSH to luminal substrates IEA Mus musculus 29132 R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 29132 R-PFA-176054 https://reactome.org/PathwayBrowser/#/R-PFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Plasmodium falciparum 29132 R-RNO-176054 https://reactome.org/PathwayBrowser/#/R-RNO-176054 GST dimers conjugate GSH with cytosolic substrates IEA Rattus norvegicus 29132 R-RNO-176059 https://reactome.org/PathwayBrowser/#/R-RNO-176059 GST trimers transfer GS from GSH to luminal substrates IEA Rattus norvegicus 29132 R-RNO-76397 https://reactome.org/PathwayBrowser/#/R-RNO-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Rattus norvegicus 29132 R-SSC-176054 https://reactome.org/PathwayBrowser/#/R-SSC-176054 GST dimers conjugate GSH with cytosolic substrates IEA Sus scrofa 29132 R-SSC-176059 https://reactome.org/PathwayBrowser/#/R-SSC-176059 GST trimers transfer GS from GSH to luminal substrates IEA Sus scrofa 29132 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa 29132 R-XTR-176054 https://reactome.org/PathwayBrowser/#/R-XTR-176054 GST dimers conjugate GSH with cytosolic substrates IEA Xenopus tropicalis 29132 R-XTR-176059 https://reactome.org/PathwayBrowser/#/R-XTR-176059 GST trimers transfer GS from GSH to luminal substrates IEA Xenopus tropicalis 29132 R-XTR-76397 https://reactome.org/PathwayBrowser/#/R-XTR-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Xenopus tropicalis 29133 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 29133 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 29133 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 29133 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 29133 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 29133 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 29133 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 29133 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 29133 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 29133 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 29133 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 29133 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 29138 R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 29138 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 29138 R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 29138 R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 29138 R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 29138 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 29138 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 29138 R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 29138 R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 29138 R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 29138 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 29138 R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 29140 R-BTA-109341 https://reactome.org/PathwayBrowser/#/R-BTA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Bos taurus 29140 R-CEL-109341 https://reactome.org/PathwayBrowser/#/R-CEL-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Caenorhabditis elegans 29140 R-CFA-109341 https://reactome.org/PathwayBrowser/#/R-CFA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Canis familiaris 29140 R-DME-109341 https://reactome.org/PathwayBrowser/#/R-DME-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Drosophila melanogaster 29140 R-GGA-109341 https://reactome.org/PathwayBrowser/#/R-GGA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Gallus gallus 29140 R-HSA-109341 https://reactome.org/PathwayBrowser/#/R-HSA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA TAS Homo sapiens 29140 R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 29140 R-MMU-109341 https://reactome.org/PathwayBrowser/#/R-MMU-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Mus musculus 29140 R-RNO-109341 https://reactome.org/PathwayBrowser/#/R-RNO-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Rattus norvegicus 29140 R-SSC-109341 https://reactome.org/PathwayBrowser/#/R-SSC-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Sus scrofa 29145 R-BTA-110244 https://reactome.org/PathwayBrowser/#/R-BTA-110244 Excision of FapyG by OGG1 glycosylase IEA Bos taurus 29145 R-BTA-5649664 https://reactome.org/PathwayBrowser/#/R-BTA-5649664 NEIL1 cleaves FapyG from damaged DNA IEA Bos taurus 29145 R-CFA-110244 https://reactome.org/PathwayBrowser/#/R-CFA-110244 Excision of FapyG by OGG1 glycosylase IEA Canis familiaris 29145 R-CFA-5649664 https://reactome.org/PathwayBrowser/#/R-CFA-5649664 NEIL1 cleaves FapyG from damaged DNA IEA Canis familiaris 29145 R-DDI-110244 https://reactome.org/PathwayBrowser/#/R-DDI-110244 Excision of FapyG by OGG1 glycosylase IEA Dictyostelium discoideum 29145 R-DME-110244 https://reactome.org/PathwayBrowser/#/R-DME-110244 Excision of FapyG by OGG1 glycosylase IEA Drosophila melanogaster 29145 R-DRE-5649664 https://reactome.org/PathwayBrowser/#/R-DRE-5649664 NEIL1 cleaves FapyG from damaged DNA IEA Danio rerio 29145 R-GGA-5649664 https://reactome.org/PathwayBrowser/#/R-GGA-5649664 NEIL1 cleaves FapyG from damaged DNA IEA Gallus gallus 29145 R-HSA-110244 https://reactome.org/PathwayBrowser/#/R-HSA-110244 Excision of FapyG by OGG1 glycosylase TAS Homo sapiens 29145 R-HSA-5649664 https://reactome.org/PathwayBrowser/#/R-HSA-5649664 NEIL1 cleaves FapyG from damaged DNA TAS Homo sapiens 29145 R-MMU-110244 https://reactome.org/PathwayBrowser/#/R-MMU-110244 Excision of FapyG by OGG1 glycosylase IEA Mus musculus 29145 R-MMU-5649664 https://reactome.org/PathwayBrowser/#/R-MMU-5649664 NEIL1 cleaves FapyG from damaged DNA IEA Mus musculus 29145 R-PFA-110244 https://reactome.org/PathwayBrowser/#/R-PFA-110244 Excision of FapyG by OGG1 glycosylase IEA Plasmodium falciparum 29145 R-RNO-110244 https://reactome.org/PathwayBrowser/#/R-RNO-110244 Excision of FapyG by OGG1 glycosylase IEA Rattus norvegicus 29145 R-RNO-5649664 https://reactome.org/PathwayBrowser/#/R-RNO-5649664 NEIL1 cleaves FapyG from damaged DNA IEA Rattus norvegicus 29145 R-SCE-110244 https://reactome.org/PathwayBrowser/#/R-SCE-110244 Excision of FapyG by OGG1 glycosylase IEA Saccharomyces cerevisiae 29145 R-SSC-5649664 https://reactome.org/PathwayBrowser/#/R-SSC-5649664 NEIL1 cleaves FapyG from damaged DNA IEA Sus scrofa 29145 R-XTR-5649664 https://reactome.org/PathwayBrowser/#/R-XTR-5649664 NEIL1 cleaves FapyG from damaged DNA IEA Xenopus tropicalis 29146 R-BTA-110250 https://reactome.org/PathwayBrowser/#/R-BTA-110250 Cleavage of ethenoadenine by MPG glycosylase IEA Bos taurus 29146 R-CFA-110250 https://reactome.org/PathwayBrowser/#/R-CFA-110250 Cleavage of ethenoadenine by MPG glycosylase IEA Canis familiaris 29146 R-DRE-110250 https://reactome.org/PathwayBrowser/#/R-DRE-110250 Cleavage of ethenoadenine by MPG glycosylase IEA Danio rerio 29146 R-GGA-110250 https://reactome.org/PathwayBrowser/#/R-GGA-110250 Cleavage of ethenoadenine by MPG glycosylase IEA Gallus gallus 29146 R-HSA-110250 https://reactome.org/PathwayBrowser/#/R-HSA-110250 Cleavage of ethenoadenine by MPG glycosylase TAS Homo sapiens 29146 R-MMU-110250 https://reactome.org/PathwayBrowser/#/R-MMU-110250 Cleavage of ethenoadenine by MPG glycosylase IEA Mus musculus 29146 R-PFA-110250 https://reactome.org/PathwayBrowser/#/R-PFA-110250 Cleavage of ethenoadenine by MPG glycosylase IEA Plasmodium falciparum 29146 R-RNO-110250 https://reactome.org/PathwayBrowser/#/R-RNO-110250 Cleavage of ethenoadenine by MPG glycosylase IEA Rattus norvegicus 29146 R-SSC-110250 https://reactome.org/PathwayBrowser/#/R-SSC-110250 Cleavage of ethenoadenine by MPG glycosylase IEA Sus scrofa 29146 R-XTR-110250 https://reactome.org/PathwayBrowser/#/R-XTR-110250 Cleavage of ethenoadenine by MPG glycosylase IEA Xenopus tropicalis 29147 R-BTA-110234 https://reactome.org/PathwayBrowser/#/R-BTA-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Bos taurus 29147 R-CFA-110234 https://reactome.org/PathwayBrowser/#/R-CFA-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Canis familiaris 29147 R-DME-110234 https://reactome.org/PathwayBrowser/#/R-DME-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Drosophila melanogaster 29147 R-DRE-110234 https://reactome.org/PathwayBrowser/#/R-DRE-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Danio rerio 29147 R-GGA-110234 https://reactome.org/PathwayBrowser/#/R-GGA-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Gallus gallus 29147 R-HSA-110234 https://reactome.org/PathwayBrowser/#/R-HSA-110234 Cleavage of ethenocytosine by TDG glycosylase TAS Homo sapiens 29147 R-MMU-110234 https://reactome.org/PathwayBrowser/#/R-MMU-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Mus musculus 29147 R-RNO-110234 https://reactome.org/PathwayBrowser/#/R-RNO-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Rattus norvegicus 29147 R-SPO-110234 https://reactome.org/PathwayBrowser/#/R-SPO-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Schizosaccharomyces pombe 29147 R-SSC-110234 https://reactome.org/PathwayBrowser/#/R-SSC-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Sus scrofa 29147 R-XTR-110234 https://reactome.org/PathwayBrowser/#/R-XTR-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Xenopus tropicalis 29152 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29152 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29152 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29152 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29152 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29152 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29152 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29152 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29152 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29152 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29152 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29152 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29152 R-HSA-379887 https://reactome.org/PathwayBrowser/#/R-HSA-379887 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate TAS Homo sapiens 29152 R-HSA-380158 https://reactome.org/PathwayBrowser/#/R-HSA-380158 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate IEA Homo sapiens 29152 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29152 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29152 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29152 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29152 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29152 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29153 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29153 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29153 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29153 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29153 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29153 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29153 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29153 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29153 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29153 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29153 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29153 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29153 R-HSA-379848 https://reactome.org/PathwayBrowser/#/R-HSA-379848 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 29153 R-HSA-380203 https://reactome.org/PathwayBrowser/#/R-HSA-380203 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 29153 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29153 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29153 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29153 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29153 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29153 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29154 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29154 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29154 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29154 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29154 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29154 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29154 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29154 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29154 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29154 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29154 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29154 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29154 R-HSA-379865 https://reactome.org/PathwayBrowser/#/R-HSA-379865 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate TAS Homo sapiens 29154 R-HSA-380198 https://reactome.org/PathwayBrowser/#/R-HSA-380198 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate IEA Homo sapiens 29154 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29154 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29154 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29154 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29154 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29154 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29155 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29155 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29155 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29155 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29155 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29155 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29155 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29155 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29155 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29155 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29155 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29155 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29155 R-HSA-379844 https://reactome.org/PathwayBrowser/#/R-HSA-379844 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 29155 R-HSA-380234 https://reactome.org/PathwayBrowser/#/R-HSA-380234 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 29155 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29155 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29155 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29155 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29155 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29155 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29156 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29156 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29156 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29156 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29156 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29156 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29156 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29156 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29156 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29156 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29156 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29156 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29156 R-HSA-380048 https://reactome.org/PathwayBrowser/#/R-HSA-380048 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 29156 R-HSA-380240 https://reactome.org/PathwayBrowser/#/R-HSA-380240 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 29156 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29156 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29156 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29156 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29156 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29156 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29157 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29157 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29157 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29157 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29157 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29157 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29157 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29157 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29157 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29157 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29157 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29157 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29157 R-HSA-379861 https://reactome.org/PathwayBrowser/#/R-HSA-379861 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 29157 R-HSA-380216 https://reactome.org/PathwayBrowser/#/R-HSA-380216 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate IEA Homo sapiens 29157 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29157 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29157 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29157 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29157 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29157 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29158 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29158 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29158 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29158 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29158 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29158 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29158 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29158 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29158 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29158 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29158 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29158 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29158 R-HSA-379867 https://reactome.org/PathwayBrowser/#/R-HSA-379867 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 29158 R-HSA-380229 https://reactome.org/PathwayBrowser/#/R-HSA-380229 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 29158 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29158 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29158 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29158 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29158 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29158 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29159 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29159 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29159 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29159 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29159 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29159 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29159 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29159 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29159 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29159 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29159 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29159 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29159 R-HSA-379977 https://reactome.org/PathwayBrowser/#/R-HSA-379977 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 29159 R-HSA-380222 https://reactome.org/PathwayBrowser/#/R-HSA-380222 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 29159 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29159 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29159 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29159 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29159 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29159 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29160 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29160 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29160 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29160 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29160 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29160 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29160 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29160 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29160 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29160 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29160 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29160 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29160 R-HSA-379893 https://reactome.org/PathwayBrowser/#/R-HSA-379893 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 29160 R-HSA-380176 https://reactome.org/PathwayBrowser/#/R-HSA-380176 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 29160 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29160 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29160 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29160 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29160 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29160 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29161 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29161 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29161 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29161 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29161 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29161 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29161 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29161 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29161 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29161 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29161 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29161 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29161 R-HSA-379980 https://reactome.org/PathwayBrowser/#/R-HSA-379980 tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 29161 R-HSA-380170 https://reactome.org/PathwayBrowser/#/R-HSA-380170 tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 29161 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29161 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29161 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29161 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29161 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29161 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29162 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29162 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29162 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29162 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29162 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29162 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29162 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29162 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29162 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29162 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29162 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29162 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29162 R-HSA-379992 https://reactome.org/PathwayBrowser/#/R-HSA-379992 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 29162 R-HSA-380239 https://reactome.org/PathwayBrowser/#/R-HSA-380239 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 29162 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29162 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29162 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29162 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29162 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29162 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29163 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29163 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29163 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29163 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29163 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29163 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29163 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29163 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29163 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29163 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29163 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29163 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29163 R-HSA-380002 https://reactome.org/PathwayBrowser/#/R-HSA-380002 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate TAS Homo sapiens 29163 R-HSA-380201 https://reactome.org/PathwayBrowser/#/R-HSA-380201 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate IEA Homo sapiens 29163 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29163 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29163 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29163 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29163 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29163 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29164 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29164 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29164 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29164 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29164 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29164 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29164 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29164 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29164 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29164 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29164 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29164 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29164 R-HSA-380042 https://reactome.org/PathwayBrowser/#/R-HSA-380042 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate TAS Homo sapiens 29164 R-HSA-380199 https://reactome.org/PathwayBrowser/#/R-HSA-380199 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate IEA Homo sapiens 29164 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29164 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29164 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29164 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29164 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29164 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29166 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29166 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29166 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29166 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29166 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29166 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29166 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29166 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29166 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29166 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29166 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29166 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29166 R-HSA-379982 https://reactome.org/PathwayBrowser/#/R-HSA-379982 glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate TAS Homo sapiens 29166 R-HSA-380241 https://reactome.org/PathwayBrowser/#/R-HSA-380241 glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 29166 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29166 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29166 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29166 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29166 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29166 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29167 R-HSA-379887 https://reactome.org/PathwayBrowser/#/R-HSA-379887 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate TAS Homo sapiens 29167 R-HSA-380158 https://reactome.org/PathwayBrowser/#/R-HSA-380158 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate IEA Homo sapiens 29167 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29167 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29167 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29167 R-HSA-8932765 https://reactome.org/PathwayBrowser/#/R-HSA-8932765 NSUN6 methylates cytidine-72 in tRNA(Cys) and tRNA(Thr) TAS Homo sapiens 29168 R-HSA-379982 https://reactome.org/PathwayBrowser/#/R-HSA-379982 glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate TAS Homo sapiens 29168 R-HSA-380241 https://reactome.org/PathwayBrowser/#/R-HSA-380241 glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 29168 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29168 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29168 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29168 R-HSA-6782264 https://reactome.org/PathwayBrowser/#/R-HSA-6782264 CTU1:CTU2:URM1 thiolates uridine-34 in tRNAs TAS Homo sapiens 29168 R-SCE-6787377 https://reactome.org/PathwayBrowser/#/R-SCE-6787377 MSS1 and MTO1 transform uridine-34 to 5-carboxymethylaminomethyluridine-34 in tRNA TAS Saccharomyces cerevisiae 29168 R-SCE-6787385 https://reactome.org/PathwayBrowser/#/R-SCE-6787385 SLM3 (MTO2, MTU1) transfers a sulfur atom to 5-carboxymethylaminomethyluridine-34 in tRNA TAS Saccharomyces cerevisiae 29169 R-HSA-379974 https://reactome.org/PathwayBrowser/#/R-HSA-379974 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 29169 R-HSA-380200 https://reactome.org/PathwayBrowser/#/R-HSA-380200 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 29169 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29169 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29169 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29169 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 29169 R-HSA-6782388 https://reactome.org/PathwayBrowser/#/R-HSA-6782388 NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) IEA Homo sapiens 29169 R-HSA-6787403 https://reactome.org/PathwayBrowser/#/R-HSA-6787403 GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA IEA Homo sapiens 29169 R-HSA-6787447 https://reactome.org/PathwayBrowser/#/R-HSA-6787447 TRMU (MTO2, MTU1) transfers a sulfur atom to 5-taurinomethyluridine-34 in tRNA IEA Homo sapiens 29169 R-HSA-6787525 https://reactome.org/PathwayBrowser/#/R-HSA-6787525 TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58 TAS Homo sapiens 29169 R-SCE-6790127 https://reactome.org/PathwayBrowser/#/R-SCE-6790127 SMM1 (DUS2) reduces uridine-20 to dihydrouridine in tRNA(Leu) TAS Saccharomyces cerevisiae 29169 R-SCE-6790189 https://reactome.org/PathwayBrowser/#/R-SCE-6790189 NCL1 (TRM4) methylates cytidine-34 of unspliced tRNA(Leu) yielding 5-methylcytidine-34 TAS Saccharomyces cerevisiae 29170 R-HSA-379864 https://reactome.org/PathwayBrowser/#/R-HSA-379864 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate TAS Homo sapiens 29170 R-HSA-380177 https://reactome.org/PathwayBrowser/#/R-HSA-380177 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate IEA Homo sapiens 29170 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29170 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29170 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29170 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 29170 R-HSA-6782336 https://reactome.org/PathwayBrowser/#/R-HSA-6782336 ADAT1 deaminates adenosine-37 in tRNA(Ala) IEA Homo sapiens 29170 R-SCE-6790128 https://reactome.org/PathwayBrowser/#/R-SCE-6790128 TAD1 deaminates adenosine-37 in tRNA(Ala) yielding inosine-37 TAS Saccharomyces cerevisiae 29171 R-HSA-379993 https://reactome.org/PathwayBrowser/#/R-HSA-379993 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 29171 R-HSA-380224 https://reactome.org/PathwayBrowser/#/R-HSA-380224 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 29171 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29171 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29171 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29171 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 29171 R-HSA-6786500 https://reactome.org/PathwayBrowser/#/R-HSA-6786500 ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 IEA Homo sapiens 29171 R-SCE-6790171 https://reactome.org/PathwayBrowser/#/R-SCE-6790171 TRM9 methylates 5-carboxymethyluridine-34 in tRNA(Arg3) yielding 5-methoxycarbonylmethyluridine-34 TAS Saccharomyces cerevisiae 29172 R-HSA-379996 https://reactome.org/PathwayBrowser/#/R-HSA-379996 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate TAS Homo sapiens 29172 R-HSA-380227 https://reactome.org/PathwayBrowser/#/R-HSA-380227 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate IEA Homo sapiens 29172 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29172 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29172 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29173 R-BTA-5432422 https://reactome.org/PathwayBrowser/#/R-BTA-5432422 Translocation of 55S ribosome by 3 bases in the 3' direction TAS Bos taurus 29173 R-HSA-2408546 https://reactome.org/PathwayBrowser/#/R-HSA-2408546 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex IEA Homo sapiens 29173 R-HSA-379994 https://reactome.org/PathwayBrowser/#/R-HSA-379994 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 29173 R-HSA-380157 https://reactome.org/PathwayBrowser/#/R-HSA-380157 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 29173 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29173 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29173 R-HSA-5419279 https://reactome.org/PathwayBrowser/#/R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) IEA Homo sapiens 29173 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29173 R-HSA-6782381 https://reactome.org/PathwayBrowser/#/R-HSA-6782381 PUS1 isoform 2 transforms uridine residues to pseudouridine in the anticodon stems of tRNAs IEA Homo sapiens 29173 R-HSA-6783492 https://reactome.org/PathwayBrowser/#/R-HSA-6783492 TRMT6:TRMT61A methylate adenosine yielding 1-methyladenosine at nucleotide 58 of tRNA(Met) TAS Homo sapiens 29173 R-TAE-2408513 https://reactome.org/PathwayBrowser/#/R-TAE-2408513 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Triticum aestivum 29173 R-VRA-2408510 https://reactome.org/PathwayBrowser/#/R-VRA-2408510 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Vigna radiata var. radiata 29174 R-HSA-379893 https://reactome.org/PathwayBrowser/#/R-HSA-379893 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 29174 R-HSA-380176 https://reactome.org/PathwayBrowser/#/R-HSA-380176 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 29174 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29174 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29174 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29174 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 29174 R-HSA-6782381 https://reactome.org/PathwayBrowser/#/R-HSA-6782381 PUS1 isoform 2 transforms uridine residues to pseudouridine in the anticodon stems of tRNAs IEA Homo sapiens 29174 R-SCE-6790166 https://reactome.org/PathwayBrowser/#/R-SCE-6790166 PUS1 transforms uridine residues to pseudouridine in unspliced tRNA(Ile,Tyr) TAS Saccharomyces cerevisiae 29175 R-HSA-379861 https://reactome.org/PathwayBrowser/#/R-HSA-379861 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 29175 R-HSA-380216 https://reactome.org/PathwayBrowser/#/R-HSA-380216 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate IEA Homo sapiens 29175 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29175 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29175 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29175 R-HSA-6782264 https://reactome.org/PathwayBrowser/#/R-HSA-6782264 CTU1:CTU2:URM1 thiolates uridine-34 in tRNAs TAS Homo sapiens 29175 R-HSA-6786500 https://reactome.org/PathwayBrowser/#/R-HSA-6786500 ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 IEA Homo sapiens 29175 R-SCE-6787377 https://reactome.org/PathwayBrowser/#/R-SCE-6787377 MSS1 and MTO1 transform uridine-34 to 5-carboxymethylaminomethyluridine-34 in tRNA TAS Saccharomyces cerevisiae 29175 R-SCE-6787385 https://reactome.org/PathwayBrowser/#/R-SCE-6787385 SLM3 (MTO2, MTU1) transfers a sulfur atom to 5-carboxymethylaminomethyluridine-34 in tRNA TAS Saccharomyces cerevisiae 29176 R-HSA-380048 https://reactome.org/PathwayBrowser/#/R-HSA-380048 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 29176 R-HSA-380240 https://reactome.org/PathwayBrowser/#/R-HSA-380240 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 29176 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29176 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29176 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29176 R-HSA-6785438 https://reactome.org/PathwayBrowser/#/R-HSA-6785438 NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) TAS Homo sapiens 29176 R-HSA-6788684 https://reactome.org/PathwayBrowser/#/R-HSA-6788684 TRMT13 2'-O-methylates cytidine-4 in tRNA IEA Homo sapiens 29176 R-SCE-6788683 https://reactome.org/PathwayBrowser/#/R-SCE-6788683 TRM13 2'-O-methylates cytidine-4 in tRNA TAS Saccharomyces cerevisiae 29177 R-HSA-379865 https://reactome.org/PathwayBrowser/#/R-HSA-379865 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate TAS Homo sapiens 29177 R-HSA-380198 https://reactome.org/PathwayBrowser/#/R-HSA-380198 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate IEA Homo sapiens 29177 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29177 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29177 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29177 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 29177 R-HSA-6788684 https://reactome.org/PathwayBrowser/#/R-HSA-6788684 TRMT13 2'-O-methylates cytidine-4 in tRNA IEA Homo sapiens 29177 R-SCE-6788683 https://reactome.org/PathwayBrowser/#/R-SCE-6788683 TRM13 2'-O-methylates cytidine-4 in tRNA TAS Saccharomyces cerevisiae 29178 R-HSA-379844 https://reactome.org/PathwayBrowser/#/R-HSA-379844 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 29178 R-HSA-380234 https://reactome.org/PathwayBrowser/#/R-HSA-380234 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 29178 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29178 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29178 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29178 R-HSA-6782434 https://reactome.org/PathwayBrowser/#/R-HSA-6782434 THG1L transfers GMP to 5' end of tRNA(His) TAS Homo sapiens 29178 R-HSA-6788668 https://reactome.org/PathwayBrowser/#/R-HSA-6788668 TRMT13 2'-O-methylates adenosine-4 in tRNA IEA Homo sapiens 29178 R-SCE-6788665 https://reactome.org/PathwayBrowser/#/R-SCE-6788665 TRM13 2'-O-methylates adenosine-4 in tRNA TAS Saccharomyces cerevisiae 29179 R-HSA-379992 https://reactome.org/PathwayBrowser/#/R-HSA-379992 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 29179 R-HSA-380239 https://reactome.org/PathwayBrowser/#/R-HSA-380239 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 29179 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29179 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29179 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29179 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 29179 R-HSA-6782381 https://reactome.org/PathwayBrowser/#/R-HSA-6782381 PUS1 isoform 2 transforms uridine residues to pseudouridine in the anticodon stems of tRNAs IEA Homo sapiens 29179 R-HSA-6787566 https://reactome.org/PathwayBrowser/#/R-HSA-6787566 PUS1 isoform 1 transforms uridine-27, uridine-28 yielding pseudouridine in tRNA(Lys,Ser) TAS Homo sapiens 29179 R-HSA-6788707 https://reactome.org/PathwayBrowser/#/R-HSA-6788707 TRMT44 2'-O-methylates uridine-44 in tRNA(Ser) IEA Homo sapiens 29179 R-SCE-6788673 https://reactome.org/PathwayBrowser/#/R-SCE-6788673 TRM44 2'-O-methylates uridine-44 in tRNA(Ser) TAS Saccharomyces cerevisiae 29180 R-HSA-380002 https://reactome.org/PathwayBrowser/#/R-HSA-380002 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate TAS Homo sapiens 29180 R-HSA-380201 https://reactome.org/PathwayBrowser/#/R-HSA-380201 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate IEA Homo sapiens 29180 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29180 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29180 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29180 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 29180 R-HSA-8932765 https://reactome.org/PathwayBrowser/#/R-HSA-8932765 NSUN6 methylates cytidine-72 in tRNA(Cys) and tRNA(Thr) TAS Homo sapiens 29181 R-HSA-379977 https://reactome.org/PathwayBrowser/#/R-HSA-379977 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 29181 R-HSA-380222 https://reactome.org/PathwayBrowser/#/R-HSA-380222 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 29181 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29181 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29181 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29182 R-HSA-379980 https://reactome.org/PathwayBrowser/#/R-HSA-379980 tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 29182 R-HSA-380170 https://reactome.org/PathwayBrowser/#/R-HSA-380170 tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 29182 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29182 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29182 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29182 R-HSA-6782416 https://reactome.org/PathwayBrowser/#/R-HSA-6782416 TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) TAS Homo sapiens 29182 R-HSA-6782443 https://reactome.org/PathwayBrowser/#/R-HSA-6782443 QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr) TAS Homo sapiens 29182 R-HSA-6786583 https://reactome.org/PathwayBrowser/#/R-HSA-6786583 PUS7 transforms uridine to pseudouridine in tRNAs IEA Homo sapiens 29182 R-SCE-6786558 https://reactome.org/PathwayBrowser/#/R-SCE-6786558 PUS7 transforms uridine to pseudouridine at nucleotide 13 of tRNA TAS Saccharomyces cerevisiae 29182 R-SCE-6790166 https://reactome.org/PathwayBrowser/#/R-SCE-6790166 PUS1 transforms uridine residues to pseudouridine in unspliced tRNA(Ile,Tyr) TAS Saccharomyces cerevisiae 29183 R-HSA-380042 https://reactome.org/PathwayBrowser/#/R-HSA-380042 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate TAS Homo sapiens 29183 R-HSA-380199 https://reactome.org/PathwayBrowser/#/R-HSA-380199 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate IEA Homo sapiens 29183 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29183 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29183 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29183 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 29184 R-HSA-379848 https://reactome.org/PathwayBrowser/#/R-HSA-379848 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 29184 R-HSA-380203 https://reactome.org/PathwayBrowser/#/R-HSA-380203 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 29184 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29184 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29184 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29184 R-HSA-6782286 https://reactome.org/PathwayBrowser/#/R-HSA-6782286 METTL1:WDR4 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 IEA Homo sapiens 29184 R-HSA-6782859 https://reactome.org/PathwayBrowser/#/R-HSA-6782859 TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 29184 R-HSA-6782879 https://reactome.org/PathwayBrowser/#/R-HSA-6782879 TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 29184 R-HSA-6782881 https://reactome.org/PathwayBrowser/#/R-HSA-6782881 LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 29184 R-HSA-6782890 https://reactome.org/PathwayBrowser/#/R-HSA-6782890 LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 29184 R-HSA-6782893 https://reactome.org/PathwayBrowser/#/R-HSA-6782893 TRMT12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 29184 R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 29184 R-HSA-6783455 https://reactome.org/PathwayBrowser/#/R-HSA-6783455 TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 29184 R-HSA-6783473 https://reactome.org/PathwayBrowser/#/R-HSA-6783473 LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 29184 R-HSA-9024159 https://reactome.org/PathwayBrowser/#/R-HSA-9024159 FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe) TAS Homo sapiens 29184 R-HSA-9024161 https://reactome.org/PathwayBrowser/#/R-HSA-9024161 FTSJ1 2'-O-methylates guanosine-34 in tRNA(Phe) TAS Homo sapiens 29184 R-SCE-6783393 https://reactome.org/PathwayBrowser/#/R-SCE-6783393 PPM2 methoxycarbonylates yW-58 yielding yW at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 29184 R-SCE-6783396 https://reactome.org/PathwayBrowser/#/R-SCE-6783396 TRM5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 29184 R-SCE-6783410 https://reactome.org/PathwayBrowser/#/R-SCE-6783410 TRM12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 29184 R-SCE-6783417 https://reactome.org/PathwayBrowser/#/R-SCE-6783417 PPM2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 29184 R-SCE-6783426 https://reactome.org/PathwayBrowser/#/R-SCE-6783426 TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 29184 R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 29184 R-SCE-6790175 https://reactome.org/PathwayBrowser/#/R-SCE-6790175 TRM8:TRM82 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 TAS Saccharomyces cerevisiae 29185 R-HSA-380008 https://reactome.org/PathwayBrowser/#/R-HSA-380008 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 29185 R-HSA-380233 https://reactome.org/PathwayBrowser/#/R-HSA-380233 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 29185 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29185 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29185 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29185 R-HSA-6782264 https://reactome.org/PathwayBrowser/#/R-HSA-6782264 CTU1:CTU2:URM1 thiolates uridine-34 in tRNAs TAS Homo sapiens 29185 R-HSA-6787403 https://reactome.org/PathwayBrowser/#/R-HSA-6787403 GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA IEA Homo sapiens 29185 R-HSA-6787447 https://reactome.org/PathwayBrowser/#/R-HSA-6787447 TRMU (MTO2, MTU1) transfers a sulfur atom to 5-taurinomethyluridine-34 in tRNA IEA Homo sapiens 29185 R-HSA-6787525 https://reactome.org/PathwayBrowser/#/R-HSA-6787525 TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58 TAS Homo sapiens 29185 R-HSA-6787566 https://reactome.org/PathwayBrowser/#/R-HSA-6787566 PUS1 isoform 1 transforms uridine-27, uridine-28 yielding pseudouridine in tRNA(Lys,Ser) TAS Homo sapiens 29185 R-SCE-6787377 https://reactome.org/PathwayBrowser/#/R-SCE-6787377 MSS1 and MTO1 transform uridine-34 to 5-carboxymethylaminomethyluridine-34 in tRNA TAS Saccharomyces cerevisiae 29185 R-SCE-6787385 https://reactome.org/PathwayBrowser/#/R-SCE-6787385 SLM3 (MTO2, MTU1) transfers a sulfur atom to 5-carboxymethylaminomethyluridine-34 in tRNA TAS Saccharomyces cerevisiae 29186 R-HSA-379867 https://reactome.org/PathwayBrowser/#/R-HSA-379867 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 29186 R-HSA-380229 https://reactome.org/PathwayBrowser/#/R-HSA-380229 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 29186 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 29186 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 29186 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 29186 R-HSA-6782419 https://reactome.org/PathwayBrowser/#/R-HSA-6782419 TRDMT1 (DNMT2) methylates cytidine-38 of tRNA(Asp) TAS Homo sapiens 29186 R-HSA-6785409 https://reactome.org/PathwayBrowser/#/R-HSA-6785409 NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) IEA Homo sapiens 29186 R-SCE-6790149 https://reactome.org/PathwayBrowser/#/R-SCE-6790149 NCL1 (TRM4) methylates cytidine-49 of tRNA(Asp) yielding 5-methylcytidine-46 TAS Saccharomyces cerevisiae 29191 R-BTA-5662662 https://reactome.org/PathwayBrowser/#/R-BTA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Bos taurus 29191 R-BTA-9707504 https://reactome.org/PathwayBrowser/#/R-BTA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Bos taurus 29191 R-BTA-9854368 https://reactome.org/PathwayBrowser/#/R-BTA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Bos taurus 29191 R-CEL-5662662 https://reactome.org/PathwayBrowser/#/R-CEL-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Caenorhabditis elegans 29191 R-CEL-9854368 https://reactome.org/PathwayBrowser/#/R-CEL-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Caenorhabditis elegans 29191 R-CFA-5662662 https://reactome.org/PathwayBrowser/#/R-CFA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Canis familiaris 29191 R-CFA-9707504 https://reactome.org/PathwayBrowser/#/R-CFA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Canis familiaris 29191 R-CFA-9854368 https://reactome.org/PathwayBrowser/#/R-CFA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Canis familiaris 29191 R-DDI-5662662 https://reactome.org/PathwayBrowser/#/R-DDI-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Dictyostelium discoideum 29191 R-DDI-9854368 https://reactome.org/PathwayBrowser/#/R-DDI-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Dictyostelium discoideum 29191 R-DME-9854368 https://reactome.org/PathwayBrowser/#/R-DME-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Drosophila melanogaster 29191 R-DRE-9707504 https://reactome.org/PathwayBrowser/#/R-DRE-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Danio rerio 29191 R-DRE-9854368 https://reactome.org/PathwayBrowser/#/R-DRE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Danio rerio 29191 R-GGA-5662662 https://reactome.org/PathwayBrowser/#/R-GGA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Gallus gallus 29191 R-GGA-9707504 https://reactome.org/PathwayBrowser/#/R-GGA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Gallus gallus 29191 R-GGA-9854368 https://reactome.org/PathwayBrowser/#/R-GGA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Gallus gallus 29191 R-HSA-5662662 https://reactome.org/PathwayBrowser/#/R-HSA-5662662 Tyrosinase oxidises tyrosine to dopaquinone TAS Homo sapiens 29191 R-HSA-6789042 https://reactome.org/PathwayBrowser/#/R-HSA-6789042 Hydroxyl-initiated lipid peroxidation TAS Homo sapiens 29191 R-HSA-6789114 https://reactome.org/PathwayBrowser/#/R-HSA-6789114 Hydroxyl radical reacts with the base and sugar moiety of DNA TAS Homo sapiens 29191 R-HSA-6789160 https://reactome.org/PathwayBrowser/#/R-HSA-6789160 Hydrogen peroxide and Fe2+ react to hydroxyl, hydroxide and Fe3+ TAS Homo sapiens 29191 R-HSA-9707504 https://reactome.org/PathwayBrowser/#/R-HSA-9707504 H2O2 oxidises ferrohemoglobin to MetHb TAS Homo sapiens 29191 R-HSA-9757462 https://reactome.org/PathwayBrowser/#/R-HSA-9757462 Hydroxyl radicals oxidize ST to 2,3-DHBA TAS Homo sapiens 29191 R-HSA-9854368 https://reactome.org/PathwayBrowser/#/R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S TAS Homo sapiens 29191 R-MMU-5662662 https://reactome.org/PathwayBrowser/#/R-MMU-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Mus musculus 29191 R-MMU-9707504 https://reactome.org/PathwayBrowser/#/R-MMU-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Mus musculus 29191 R-MMU-9854368 https://reactome.org/PathwayBrowser/#/R-MMU-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Mus musculus 29191 R-RNO-5662662 https://reactome.org/PathwayBrowser/#/R-RNO-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Rattus norvegicus 29191 R-RNO-9707504 https://reactome.org/PathwayBrowser/#/R-RNO-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Rattus norvegicus 29191 R-RNO-9854368 https://reactome.org/PathwayBrowser/#/R-RNO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Rattus norvegicus 29191 R-SCE-9854368 https://reactome.org/PathwayBrowser/#/R-SCE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Saccharomyces cerevisiae 29191 R-SPO-9854368 https://reactome.org/PathwayBrowser/#/R-SPO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Schizosaccharomyces pombe 29191 R-SSC-5662662 https://reactome.org/PathwayBrowser/#/R-SSC-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Sus scrofa 29191 R-SSC-9707504 https://reactome.org/PathwayBrowser/#/R-SSC-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Sus scrofa 29191 R-SSC-9854368 https://reactome.org/PathwayBrowser/#/R-SSC-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Sus scrofa 29191 R-XTR-5662662 https://reactome.org/PathwayBrowser/#/R-XTR-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Xenopus tropicalis 29191 R-XTR-9707504 https://reactome.org/PathwayBrowser/#/R-XTR-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Xenopus tropicalis 29191 R-XTR-9854368 https://reactome.org/PathwayBrowser/#/R-XTR-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Xenopus tropicalis 29242 R-BTA-5696220 https://reactome.org/PathwayBrowser/#/R-BTA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Bos taurus 29242 R-DRE-5696220 https://reactome.org/PathwayBrowser/#/R-DRE-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Danio rerio 29242 R-GGA-5696220 https://reactome.org/PathwayBrowser/#/R-GGA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Gallus gallus 29242 R-HSA-5696220 https://reactome.org/PathwayBrowser/#/R-HSA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) TAS Homo sapiens 29242 R-MMU-5696220 https://reactome.org/PathwayBrowser/#/R-MMU-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Mus musculus 29242 R-RNO-5696220 https://reactome.org/PathwayBrowser/#/R-RNO-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Rattus norvegicus 29242 R-SSC-5696220 https://reactome.org/PathwayBrowser/#/R-SSC-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Sus scrofa 29242 R-XTR-5696220 https://reactome.org/PathwayBrowser/#/R-XTR-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Xenopus tropicalis 29264 R-HSA-2408526 https://reactome.org/PathwayBrowser/#/R-HSA-2408526 tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer TAS Homo sapiens 29264 R-HSA-5333615 https://reactome.org/PathwayBrowser/#/R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC IEA Homo sapiens 29264 R-RNO-5333610 https://reactome.org/PathwayBrowser/#/R-RNO-5333610 Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec-tRNA(Sec):Eefsec:GTP is hydrolysed to Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec and Eefsec:GDP by Eefsec TAS Rattus norvegicus 29265 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 29265 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 29265 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 29265 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 29265 R-ECO-159884 https://reactome.org/PathwayBrowser/#/R-ECO-159884 Peptide transfer from P-site tRNA to the A-site tRNA TAS Escherichia coli 29265 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 29265 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 29265 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 29265 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 29265 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 29265 R-HSA-192704 https://reactome.org/PathwayBrowser/#/R-HSA-192704 Synthesis of PB1-F2 TAS Homo sapiens 29265 R-HSA-192841 https://reactome.org/PathwayBrowser/#/R-HSA-192841 Viral Protein Synthesis TAS Homo sapiens 29265 R-HSA-379996 https://reactome.org/PathwayBrowser/#/R-HSA-379996 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate TAS Homo sapiens 29265 R-HSA-380227 https://reactome.org/PathwayBrowser/#/R-HSA-380227 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate IEA Homo sapiens 29265 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 29265 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 29265 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 29265 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 29265 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 29265 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 29452 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 29452 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 29452 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 29452 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 29452 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 29452 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 29452 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 29452 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 29452 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 2948 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 2948 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 2948 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 2948 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 2948 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 2948 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 2948 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 2948 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 2948 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 2948 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 295975 R-BTA-1605797 https://reactome.org/PathwayBrowser/#/R-BTA-1605797 SMPD1 hydrolyzes SPHM IEA Bos taurus 295975 R-BTA-1606273 https://reactome.org/PathwayBrowser/#/R-BTA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Bos taurus 295975 R-BTA-1640164 https://reactome.org/PathwayBrowser/#/R-BTA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Bos taurus 295975 R-CEL-1605797 https://reactome.org/PathwayBrowser/#/R-CEL-1605797 SMPD1 hydrolyzes SPHM IEA Caenorhabditis elegans 295975 R-CEL-1606273 https://reactome.org/PathwayBrowser/#/R-CEL-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Caenorhabditis elegans 295975 R-CEL-1640164 https://reactome.org/PathwayBrowser/#/R-CEL-1640164 ENPP7 hydrolyzes sphingomyelin IEA Caenorhabditis elegans 295975 R-CFA-1605797 https://reactome.org/PathwayBrowser/#/R-CFA-1605797 SMPD1 hydrolyzes SPHM IEA Canis familiaris 295975 R-CFA-1606273 https://reactome.org/PathwayBrowser/#/R-CFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Canis familiaris 295975 R-CFA-1640164 https://reactome.org/PathwayBrowser/#/R-CFA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Canis familiaris 295975 R-DDI-1605797 https://reactome.org/PathwayBrowser/#/R-DDI-1605797 SMPD1 hydrolyzes SPHM IEA Dictyostelium discoideum 295975 R-DDI-1606273 https://reactome.org/PathwayBrowser/#/R-DDI-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Dictyostelium discoideum 295975 R-DDI-1640164 https://reactome.org/PathwayBrowser/#/R-DDI-1640164 ENPP7 hydrolyzes sphingomyelin IEA Dictyostelium discoideum 295975 R-DME-1605797 https://reactome.org/PathwayBrowser/#/R-DME-1605797 SMPD1 hydrolyzes SPHM IEA Drosophila melanogaster 295975 R-DME-1606273 https://reactome.org/PathwayBrowser/#/R-DME-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Drosophila melanogaster 295975 R-DRE-1606273 https://reactome.org/PathwayBrowser/#/R-DRE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Danio rerio 295975 R-GGA-1605797 https://reactome.org/PathwayBrowser/#/R-GGA-1605797 SMPD1 hydrolyzes SPHM IEA Gallus gallus 295975 R-GGA-1606273 https://reactome.org/PathwayBrowser/#/R-GGA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Gallus gallus 295975 R-GGA-1640164 https://reactome.org/PathwayBrowser/#/R-GGA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Gallus gallus 295975 R-HSA-1605797 https://reactome.org/PathwayBrowser/#/R-HSA-1605797 SMPD1 hydrolyzes SPHM TAS Homo sapiens 295975 R-HSA-1606273 https://reactome.org/PathwayBrowser/#/R-HSA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) TAS Homo sapiens 295975 R-HSA-1640164 https://reactome.org/PathwayBrowser/#/R-HSA-1640164 ENPP7 hydrolyzes sphingomyelin TAS Homo sapiens 295975 R-MMU-1605797 https://reactome.org/PathwayBrowser/#/R-MMU-1605797 SMPD1 hydrolyzes SPHM IEA Mus musculus 295975 R-MMU-1606273 https://reactome.org/PathwayBrowser/#/R-MMU-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Mus musculus 295975 R-MMU-1640164 https://reactome.org/PathwayBrowser/#/R-MMU-1640164 ENPP7 hydrolyzes sphingomyelin IEA Mus musculus 295975 R-PFA-1606273 https://reactome.org/PathwayBrowser/#/R-PFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Plasmodium falciparum 295975 R-RNO-1605797 https://reactome.org/PathwayBrowser/#/R-RNO-1605797 SMPD1 hydrolyzes SPHM IEA Rattus norvegicus 295975 R-RNO-1606273 https://reactome.org/PathwayBrowser/#/R-RNO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Rattus norvegicus 295975 R-RNO-1640164 https://reactome.org/PathwayBrowser/#/R-RNO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Rattus norvegicus 295975 R-SCE-1606273 https://reactome.org/PathwayBrowser/#/R-SCE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Saccharomyces cerevisiae 295975 R-SCE-1640164 https://reactome.org/PathwayBrowser/#/R-SCE-1640164 ENPP7 hydrolyzes sphingomyelin IEA Saccharomyces cerevisiae 295975 R-SPO-1606273 https://reactome.org/PathwayBrowser/#/R-SPO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Schizosaccharomyces pombe 295975 R-SPO-1640164 https://reactome.org/PathwayBrowser/#/R-SPO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Schizosaccharomyces pombe 295975 R-SSC-1605797 https://reactome.org/PathwayBrowser/#/R-SSC-1605797 SMPD1 hydrolyzes SPHM IEA Sus scrofa 295975 R-SSC-1606273 https://reactome.org/PathwayBrowser/#/R-SSC-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Sus scrofa 295975 R-SSC-1640164 https://reactome.org/PathwayBrowser/#/R-SSC-1640164 ENPP7 hydrolyzes sphingomyelin IEA Sus scrofa 295975 R-XTR-1605797 https://reactome.org/PathwayBrowser/#/R-XTR-1605797 SMPD1 hydrolyzes SPHM IEA Xenopus tropicalis 295975 R-XTR-1606273 https://reactome.org/PathwayBrowser/#/R-XTR-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Xenopus tropicalis 295975 R-XTR-1640164 https://reactome.org/PathwayBrowser/#/R-XTR-1640164 ENPP7 hydrolyzes sphingomyelin IEA Xenopus tropicalis 29687 R-HSA-9685655 https://reactome.org/PathwayBrowser/#/R-HSA-9685655 CTSL bind CTSL inhibitors TAS Homo sapiens 29687 R-HSA-9686710 https://reactome.org/PathwayBrowser/#/R-HSA-9686710 Cleavage of S protein into S1:S2 TAS Homo sapiens 29687 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 29744 R-BTA-176588 https://reactome.org/PathwayBrowser/#/R-BTA-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Bos taurus 29744 R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 29744 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 29744 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 29744 R-BTA-194187 https://reactome.org/PathwayBrowser/#/R-BTA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Bos taurus 29744 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 29744 R-BTA-444654 https://reactome.org/PathwayBrowser/#/R-BTA-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Bos taurus 29744 R-BTA-5340195 https://reactome.org/PathwayBrowser/#/R-BTA-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Bos taurus 29744 R-BTA-5340251 https://reactome.org/PathwayBrowser/#/R-BTA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Bos taurus 29744 R-BTA-8873850 https://reactome.org/PathwayBrowser/#/R-BTA-8873850 STARD5 binds DCA, LCA IEA Bos taurus 29744 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 29744 R-CEL-444654 https://reactome.org/PathwayBrowser/#/R-CEL-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Caenorhabditis elegans 29744 R-CEL-8873850 https://reactome.org/PathwayBrowser/#/R-CEL-8873850 STARD5 binds DCA, LCA IEA Caenorhabditis elegans 29744 R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 29744 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 29744 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 29744 R-CFA-194187 https://reactome.org/PathwayBrowser/#/R-CFA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Canis familiaris 29744 R-CFA-444654 https://reactome.org/PathwayBrowser/#/R-CFA-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Canis familiaris 29744 R-CFA-5340195 https://reactome.org/PathwayBrowser/#/R-CFA-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Canis familiaris 29744 R-CFA-5340251 https://reactome.org/PathwayBrowser/#/R-CFA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Canis familiaris 29744 R-CFA-8873850 https://reactome.org/PathwayBrowser/#/R-CFA-8873850 STARD5 binds DCA, LCA IEA Canis familiaris 29744 R-DME-176588 https://reactome.org/PathwayBrowser/#/R-DME-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Drosophila melanogaster 29744 R-DME-194187 https://reactome.org/PathwayBrowser/#/R-DME-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29744 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 29744 R-DME-444654 https://reactome.org/PathwayBrowser/#/R-DME-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Drosophila melanogaster 29744 R-DME-5340195 https://reactome.org/PathwayBrowser/#/R-DME-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Drosophila melanogaster 29744 R-DME-5340251 https://reactome.org/PathwayBrowser/#/R-DME-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Drosophila melanogaster 29744 R-DRE-176588 https://reactome.org/PathwayBrowser/#/R-DRE-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Danio rerio 29744 R-DRE-194187 https://reactome.org/PathwayBrowser/#/R-DRE-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Danio rerio 29744 R-DRE-5340195 https://reactome.org/PathwayBrowser/#/R-DRE-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Danio rerio 29744 R-GGA-176588 https://reactome.org/PathwayBrowser/#/R-GGA-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Gallus gallus 29744 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 29744 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 29744 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 29744 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus 29744 R-GGA-5340195 https://reactome.org/PathwayBrowser/#/R-GGA-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Gallus gallus 29744 R-GGA-5340251 https://reactome.org/PathwayBrowser/#/R-GGA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Gallus gallus 29744 R-GGA-8873850 https://reactome.org/PathwayBrowser/#/R-GGA-8873850 STARD5 binds DCA, LCA IEA Gallus gallus 29744 R-HSA-176588 https://reactome.org/PathwayBrowser/#/R-HSA-176588 lithocholate + PAPS => lithocholate sulfate + PAP TAS Homo sapiens 29744 R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 29744 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 29744 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 29744 R-HSA-194187 https://reactome.org/PathwayBrowser/#/R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol TAS Homo sapiens 29744 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 29744 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 29744 R-HSA-444654 https://reactome.org/PathwayBrowser/#/R-HSA-444654 G-protein coupled bile acid receptor binds lithocholic acid TAS Homo sapiens 29744 R-HSA-5340195 https://reactome.org/PathwayBrowser/#/R-HSA-5340195 NR1H4 binds DCA, CDCA, LCHA TAS Homo sapiens 29744 R-HSA-5340251 https://reactome.org/PathwayBrowser/#/R-HSA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 TAS Homo sapiens 29744 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 29744 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 29744 R-HSA-8873850 https://reactome.org/PathwayBrowser/#/R-HSA-8873850 STARD5 binds DCA, LCA TAS Homo sapiens 29744 R-MMU-176588 https://reactome.org/PathwayBrowser/#/R-MMU-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Mus musculus 29744 R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 29744 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 29744 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 29744 R-MMU-194187 https://reactome.org/PathwayBrowser/#/R-MMU-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Mus musculus 29744 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 29744 R-MMU-444654 https://reactome.org/PathwayBrowser/#/R-MMU-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Mus musculus 29744 R-MMU-5340195 https://reactome.org/PathwayBrowser/#/R-MMU-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Mus musculus 29744 R-MMU-5340251 https://reactome.org/PathwayBrowser/#/R-MMU-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Mus musculus 29744 R-MMU-8873850 https://reactome.org/PathwayBrowser/#/R-MMU-8873850 STARD5 binds DCA, LCA IEA Mus musculus 29744 R-RNO-176588 https://reactome.org/PathwayBrowser/#/R-RNO-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Rattus norvegicus 29744 R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 29744 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 29744 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 29744 R-RNO-194187 https://reactome.org/PathwayBrowser/#/R-RNO-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Rattus norvegicus 29744 R-RNO-444654 https://reactome.org/PathwayBrowser/#/R-RNO-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Rattus norvegicus 29744 R-RNO-5340195 https://reactome.org/PathwayBrowser/#/R-RNO-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Rattus norvegicus 29744 R-RNO-5340251 https://reactome.org/PathwayBrowser/#/R-RNO-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Rattus norvegicus 29744 R-RNO-8873850 https://reactome.org/PathwayBrowser/#/R-RNO-8873850 STARD5 binds DCA, LCA IEA Rattus norvegicus 29744 R-SSC-176588 https://reactome.org/PathwayBrowser/#/R-SSC-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Sus scrofa 29744 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 29744 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 29744 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 29744 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa 29744 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 29744 R-SSC-444654 https://reactome.org/PathwayBrowser/#/R-SSC-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Sus scrofa 29744 R-SSC-5340195 https://reactome.org/PathwayBrowser/#/R-SSC-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Sus scrofa 29744 R-SSC-5340251 https://reactome.org/PathwayBrowser/#/R-SSC-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Sus scrofa 29744 R-SSC-8873850 https://reactome.org/PathwayBrowser/#/R-SSC-8873850 STARD5 binds DCA, LCA IEA Sus scrofa 29744 R-XTR-176588 https://reactome.org/PathwayBrowser/#/R-XTR-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Xenopus tropicalis 29744 R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 29744 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 29744 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 29744 R-XTR-194187 https://reactome.org/PathwayBrowser/#/R-XTR-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29744 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 29744 R-XTR-444654 https://reactome.org/PathwayBrowser/#/R-XTR-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Xenopus tropicalis 29744 R-XTR-5340195 https://reactome.org/PathwayBrowser/#/R-XTR-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Xenopus tropicalis 29744 R-XTR-8873850 https://reactome.org/PathwayBrowser/#/R-XTR-8873850 STARD5 binds DCA, LCA IEA Xenopus tropicalis 29746 R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 29746 R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 29746 R-BTA-192430 https://reactome.org/PathwayBrowser/#/R-BTA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 29746 R-BTA-193362 https://reactome.org/PathwayBrowser/#/R-BTA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Bos taurus 29746 R-BTA-194079 https://reactome.org/PathwayBrowser/#/R-BTA-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Bos taurus 29746 R-BTA-194083 https://reactome.org/PathwayBrowser/#/R-BTA-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Bos taurus 29746 R-BTA-194121 https://reactome.org/PathwayBrowser/#/R-BTA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Bos taurus 29746 R-BTA-194130 https://reactome.org/PathwayBrowser/#/R-BTA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Bos taurus 29746 R-BTA-194153 https://reactome.org/PathwayBrowser/#/R-BTA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Bos taurus 29746 R-BTA-194187 https://reactome.org/PathwayBrowser/#/R-BTA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Bos taurus 29746 R-BTA-9733545 https://reactome.org/PathwayBrowser/#/R-BTA-9733545 Bile salts and acids bind ALB IEA Bos taurus 29746 R-BTA-9733960 https://reactome.org/PathwayBrowser/#/R-BTA-9733960 Bile salts and acids dissociate from ALB IEA Bos taurus 29746 R-BTA-9733964 https://reactome.org/PathwayBrowser/#/R-BTA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Bos taurus 29746 R-BTA-9733969 https://reactome.org/PathwayBrowser/#/R-BTA-9733969 Bile salts dissociate from FABP6 IEA Bos taurus 29746 R-BTA-9733973 https://reactome.org/PathwayBrowser/#/R-BTA-9733973 Bile salts bind FABP6 IEA Bos taurus 29746 R-CEL-159431 https://reactome.org/PathwayBrowser/#/R-CEL-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Caenorhabditis elegans 29746 R-CEL-192312 https://reactome.org/PathwayBrowser/#/R-CEL-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Caenorhabditis elegans 29746 R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 29746 R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 29746 R-CEL-192430 https://reactome.org/PathwayBrowser/#/R-CEL-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 29746 R-CEL-194079 https://reactome.org/PathwayBrowser/#/R-CEL-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Caenorhabditis elegans 29746 R-CEL-194083 https://reactome.org/PathwayBrowser/#/R-CEL-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Caenorhabditis elegans 29746 R-CEL-194121 https://reactome.org/PathwayBrowser/#/R-CEL-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29746 R-CEL-194130 https://reactome.org/PathwayBrowser/#/R-CEL-194130 Transport (influx) of bile salts and acids by OATP-A IEA Caenorhabditis elegans 29746 R-CEL-194153 https://reactome.org/PathwayBrowser/#/R-CEL-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Caenorhabditis elegans 29746 R-CEL-194187 https://reactome.org/PathwayBrowser/#/R-CEL-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29746 R-CEL-9733969 https://reactome.org/PathwayBrowser/#/R-CEL-9733969 Bile salts dissociate from FABP6 IEA Caenorhabditis elegans 29746 R-CEL-9733973 https://reactome.org/PathwayBrowser/#/R-CEL-9733973 Bile salts bind FABP6 IEA Caenorhabditis elegans 29746 R-CFA-159431 https://reactome.org/PathwayBrowser/#/R-CFA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Canis familiaris 29746 R-CFA-192312 https://reactome.org/PathwayBrowser/#/R-CFA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Canis familiaris 29746 R-CFA-193362 https://reactome.org/PathwayBrowser/#/R-CFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Canis familiaris 29746 R-CFA-194079 https://reactome.org/PathwayBrowser/#/R-CFA-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Canis familiaris 29746 R-CFA-194083 https://reactome.org/PathwayBrowser/#/R-CFA-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Canis familiaris 29746 R-CFA-194121 https://reactome.org/PathwayBrowser/#/R-CFA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Canis familiaris 29746 R-CFA-194130 https://reactome.org/PathwayBrowser/#/R-CFA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Canis familiaris 29746 R-CFA-194153 https://reactome.org/PathwayBrowser/#/R-CFA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Canis familiaris 29746 R-CFA-194187 https://reactome.org/PathwayBrowser/#/R-CFA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Canis familiaris 29746 R-CFA-9733545 https://reactome.org/PathwayBrowser/#/R-CFA-9733545 Bile salts and acids bind ALB IEA Canis familiaris 29746 R-CFA-9733960 https://reactome.org/PathwayBrowser/#/R-CFA-9733960 Bile salts and acids dissociate from ALB IEA Canis familiaris 29746 R-CFA-9733964 https://reactome.org/PathwayBrowser/#/R-CFA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Canis familiaris 29746 R-DDI-193362 https://reactome.org/PathwayBrowser/#/R-DDI-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 29746 R-DDI-194153 https://reactome.org/PathwayBrowser/#/R-DDI-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 29746 R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 29746 R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 29746 R-DME-192430 https://reactome.org/PathwayBrowser/#/R-DME-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 29746 R-DME-194079 https://reactome.org/PathwayBrowser/#/R-DME-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Drosophila melanogaster 29746 R-DME-194083 https://reactome.org/PathwayBrowser/#/R-DME-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Drosophila melanogaster 29746 R-DME-194121 https://reactome.org/PathwayBrowser/#/R-DME-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29746 R-DME-194130 https://reactome.org/PathwayBrowser/#/R-DME-194130 Transport (influx) of bile salts and acids by OATP-A IEA Drosophila melanogaster 29746 R-DME-194153 https://reactome.org/PathwayBrowser/#/R-DME-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Drosophila melanogaster 29746 R-DME-194187 https://reactome.org/PathwayBrowser/#/R-DME-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29746 R-DME-9733969 https://reactome.org/PathwayBrowser/#/R-DME-9733969 Bile salts dissociate from FABP6 IEA Drosophila melanogaster 29746 R-DME-9733973 https://reactome.org/PathwayBrowser/#/R-DME-9733973 Bile salts bind FABP6 IEA Drosophila melanogaster 29746 R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 29746 R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 29746 R-DRE-192430 https://reactome.org/PathwayBrowser/#/R-DRE-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 29746 R-DRE-194079 https://reactome.org/PathwayBrowser/#/R-DRE-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Danio rerio 29746 R-DRE-194083 https://reactome.org/PathwayBrowser/#/R-DRE-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Danio rerio 29746 R-DRE-194121 https://reactome.org/PathwayBrowser/#/R-DRE-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Danio rerio 29746 R-DRE-194130 https://reactome.org/PathwayBrowser/#/R-DRE-194130 Transport (influx) of bile salts and acids by OATP-A IEA Danio rerio 29746 R-DRE-194187 https://reactome.org/PathwayBrowser/#/R-DRE-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Danio rerio 29746 R-DRE-9733969 https://reactome.org/PathwayBrowser/#/R-DRE-9733969 Bile salts dissociate from FABP6 IEA Danio rerio 29746 R-DRE-9733973 https://reactome.org/PathwayBrowser/#/R-DRE-9733973 Bile salts bind FABP6 IEA Danio rerio 29746 R-GGA-159431 https://reactome.org/PathwayBrowser/#/R-GGA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Gallus gallus 29746 R-GGA-192312 https://reactome.org/PathwayBrowser/#/R-GGA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Gallus gallus 29746 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 29746 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 29746 R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 29746 R-GGA-193362 https://reactome.org/PathwayBrowser/#/R-GGA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Gallus gallus 29746 R-GGA-194079 https://reactome.org/PathwayBrowser/#/R-GGA-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Gallus gallus 29746 R-GGA-194083 https://reactome.org/PathwayBrowser/#/R-GGA-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Gallus gallus 29746 R-GGA-194130 https://reactome.org/PathwayBrowser/#/R-GGA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Gallus gallus 29746 R-GGA-194153 https://reactome.org/PathwayBrowser/#/R-GGA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Gallus gallus 29746 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus 29746 R-GGA-9733545 https://reactome.org/PathwayBrowser/#/R-GGA-9733545 Bile salts and acids bind ALB IEA Gallus gallus 29746 R-GGA-9733960 https://reactome.org/PathwayBrowser/#/R-GGA-9733960 Bile salts and acids dissociate from ALB IEA Gallus gallus 29746 R-GGA-9733964 https://reactome.org/PathwayBrowser/#/R-GGA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Gallus gallus 29746 R-GGA-9733969 https://reactome.org/PathwayBrowser/#/R-GGA-9733969 Bile salts dissociate from FABP6 IEA Gallus gallus 29746 R-GGA-9733973 https://reactome.org/PathwayBrowser/#/R-GGA-9733973 Bile salts bind FABP6 IEA Gallus gallus 29746 R-HSA-159431 https://reactome.org/PathwayBrowser/#/R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine TAS Homo sapiens 29746 R-HSA-192312 https://reactome.org/PathwayBrowser/#/R-HSA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate TAS Homo sapiens 29746 R-HSA-192315 https://reactome.org/PathwayBrowser/#/R-HSA-192315 Bile salts are translocated from the peroxisomal matrix to the cytosol TAS Homo sapiens 29746 R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 29746 R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 29746 R-HSA-192430 https://reactome.org/PathwayBrowser/#/R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 29746 R-HSA-193362 https://reactome.org/PathwayBrowser/#/R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region TAS Homo sapiens 29746 R-HSA-194079 https://reactome.org/PathwayBrowser/#/R-HSA-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol TAS Homo sapiens 29746 R-HSA-194083 https://reactome.org/PathwayBrowser/#/R-HSA-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol TAS Homo sapiens 29746 R-HSA-194121 https://reactome.org/PathwayBrowser/#/R-HSA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol TAS Homo sapiens 29746 R-HSA-194130 https://reactome.org/PathwayBrowser/#/R-HSA-194130 Transport (influx) of bile salts and acids by OATP-A TAS Homo sapiens 29746 R-HSA-194153 https://reactome.org/PathwayBrowser/#/R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region TAS Homo sapiens 29746 R-HSA-194187 https://reactome.org/PathwayBrowser/#/R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol TAS Homo sapiens 29746 R-HSA-5678517 https://reactome.org/PathwayBrowser/#/R-HSA-5678517 Defective ABCB11 does not transport bile salts from cytosol to extracellular region TAS Homo sapiens 29746 R-HSA-9733545 https://reactome.org/PathwayBrowser/#/R-HSA-9733545 Bile salts and acids bind ALB TAS Homo sapiens 29746 R-HSA-9733960 https://reactome.org/PathwayBrowser/#/R-HSA-9733960 Bile salts and acids dissociate from ALB TAS Homo sapiens 29746 R-HSA-9733964 https://reactome.org/PathwayBrowser/#/R-HSA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region TAS Homo sapiens 29746 R-HSA-9733969 https://reactome.org/PathwayBrowser/#/R-HSA-9733969 Bile salts dissociate from FABP6 TAS Homo sapiens 29746 R-HSA-9733973 https://reactome.org/PathwayBrowser/#/R-HSA-9733973 Bile salts bind FABP6 TAS Homo sapiens 29746 R-MMU-159431 https://reactome.org/PathwayBrowser/#/R-MMU-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Mus musculus 29746 R-MMU-192312 https://reactome.org/PathwayBrowser/#/R-MMU-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Mus musculus 29746 R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 29746 R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 29746 R-MMU-192430 https://reactome.org/PathwayBrowser/#/R-MMU-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 29746 R-MMU-193362 https://reactome.org/PathwayBrowser/#/R-MMU-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Mus musculus 29746 R-MMU-194079 https://reactome.org/PathwayBrowser/#/R-MMU-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Mus musculus 29746 R-MMU-194083 https://reactome.org/PathwayBrowser/#/R-MMU-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Mus musculus 29746 R-MMU-194121 https://reactome.org/PathwayBrowser/#/R-MMU-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Mus musculus 29746 R-MMU-194130 https://reactome.org/PathwayBrowser/#/R-MMU-194130 Transport (influx) of bile salts and acids by OATP-A IEA Mus musculus 29746 R-MMU-194153 https://reactome.org/PathwayBrowser/#/R-MMU-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Mus musculus 29746 R-MMU-194187 https://reactome.org/PathwayBrowser/#/R-MMU-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Mus musculus 29746 R-MMU-9733545 https://reactome.org/PathwayBrowser/#/R-MMU-9733545 Bile salts and acids bind ALB IEA Mus musculus 29746 R-MMU-9733960 https://reactome.org/PathwayBrowser/#/R-MMU-9733960 Bile salts and acids dissociate from ALB IEA Mus musculus 29746 R-MMU-9733964 https://reactome.org/PathwayBrowser/#/R-MMU-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Mus musculus 29746 R-MMU-9733969 https://reactome.org/PathwayBrowser/#/R-MMU-9733969 Bile salts dissociate from FABP6 IEA Mus musculus 29746 R-MMU-9733973 https://reactome.org/PathwayBrowser/#/R-MMU-9733973 Bile salts bind FABP6 IEA Mus musculus 29746 R-PFA-193362 https://reactome.org/PathwayBrowser/#/R-PFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Plasmodium falciparum 29746 R-RNO-159431 https://reactome.org/PathwayBrowser/#/R-RNO-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Rattus norvegicus 29746 R-RNO-192312 https://reactome.org/PathwayBrowser/#/R-RNO-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Rattus norvegicus 29746 R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 29746 R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 29746 R-RNO-192430 https://reactome.org/PathwayBrowser/#/R-RNO-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 29746 R-RNO-193362 https://reactome.org/PathwayBrowser/#/R-RNO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 29746 R-RNO-194079 https://reactome.org/PathwayBrowser/#/R-RNO-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Rattus norvegicus 29746 R-RNO-194083 https://reactome.org/PathwayBrowser/#/R-RNO-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Rattus norvegicus 29746 R-RNO-194121 https://reactome.org/PathwayBrowser/#/R-RNO-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Rattus norvegicus 29746 R-RNO-194130 https://reactome.org/PathwayBrowser/#/R-RNO-194130 Transport (influx) of bile salts and acids by OATP-A IEA Rattus norvegicus 29746 R-RNO-194153 https://reactome.org/PathwayBrowser/#/R-RNO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 29746 R-RNO-194187 https://reactome.org/PathwayBrowser/#/R-RNO-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Rattus norvegicus 29746 R-RNO-9733545 https://reactome.org/PathwayBrowser/#/R-RNO-9733545 Bile salts and acids bind ALB IEA Rattus norvegicus 29746 R-RNO-9733960 https://reactome.org/PathwayBrowser/#/R-RNO-9733960 Bile salts and acids dissociate from ALB IEA Rattus norvegicus 29746 R-RNO-9733964 https://reactome.org/PathwayBrowser/#/R-RNO-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 29746 R-RNO-9733969 https://reactome.org/PathwayBrowser/#/R-RNO-9733969 Bile salts dissociate from FABP6 IEA Rattus norvegicus 29746 R-RNO-9733973 https://reactome.org/PathwayBrowser/#/R-RNO-9733973 Bile salts bind FABP6 IEA Rattus norvegicus 29746 R-SCE-194153 https://reactome.org/PathwayBrowser/#/R-SCE-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Saccharomyces cerevisiae 29746 R-SPO-193362 https://reactome.org/PathwayBrowser/#/R-SPO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 29746 R-SPO-194153 https://reactome.org/PathwayBrowser/#/R-SPO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 29746 R-SSC-159431 https://reactome.org/PathwayBrowser/#/R-SSC-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Sus scrofa 29746 R-SSC-192312 https://reactome.org/PathwayBrowser/#/R-SSC-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Sus scrofa 29746 R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 29746 R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 29746 R-SSC-192430 https://reactome.org/PathwayBrowser/#/R-SSC-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 29746 R-SSC-193362 https://reactome.org/PathwayBrowser/#/R-SSC-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Sus scrofa 29746 R-SSC-194079 https://reactome.org/PathwayBrowser/#/R-SSC-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Sus scrofa 29746 R-SSC-194083 https://reactome.org/PathwayBrowser/#/R-SSC-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Sus scrofa 29746 R-SSC-194121 https://reactome.org/PathwayBrowser/#/R-SSC-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Sus scrofa 29746 R-SSC-194130 https://reactome.org/PathwayBrowser/#/R-SSC-194130 Transport (influx) of bile salts and acids by OATP-A IEA Sus scrofa 29746 R-SSC-194153 https://reactome.org/PathwayBrowser/#/R-SSC-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Sus scrofa 29746 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa 29746 R-SSC-9733545 https://reactome.org/PathwayBrowser/#/R-SSC-9733545 Bile salts and acids bind ALB IEA Sus scrofa 29746 R-SSC-9733960 https://reactome.org/PathwayBrowser/#/R-SSC-9733960 Bile salts and acids dissociate from ALB IEA Sus scrofa 29746 R-SSC-9733964 https://reactome.org/PathwayBrowser/#/R-SSC-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Sus scrofa 29746 R-SSC-9733969 https://reactome.org/PathwayBrowser/#/R-SSC-9733969 Bile salts dissociate from FABP6 IEA Sus scrofa 29746 R-SSC-9733973 https://reactome.org/PathwayBrowser/#/R-SSC-9733973 Bile salts bind FABP6 IEA Sus scrofa 29746 R-XTR-159431 https://reactome.org/PathwayBrowser/#/R-XTR-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Xenopus tropicalis 29746 R-XTR-192312 https://reactome.org/PathwayBrowser/#/R-XTR-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Xenopus tropicalis 29746 R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 29746 R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 29746 R-XTR-192430 https://reactome.org/PathwayBrowser/#/R-XTR-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 29746 R-XTR-194079 https://reactome.org/PathwayBrowser/#/R-XTR-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Xenopus tropicalis 29746 R-XTR-194083 https://reactome.org/PathwayBrowser/#/R-XTR-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Xenopus tropicalis 29746 R-XTR-194121 https://reactome.org/PathwayBrowser/#/R-XTR-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29746 R-XTR-194153 https://reactome.org/PathwayBrowser/#/R-XTR-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 29746 R-XTR-194187 https://reactome.org/PathwayBrowser/#/R-XTR-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29746 R-XTR-9733545 https://reactome.org/PathwayBrowser/#/R-XTR-9733545 Bile salts and acids bind ALB IEA Xenopus tropicalis 29746 R-XTR-9733960 https://reactome.org/PathwayBrowser/#/R-XTR-9733960 Bile salts and acids dissociate from ALB IEA Xenopus tropicalis 29746 R-XTR-9733964 https://reactome.org/PathwayBrowser/#/R-XTR-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 29746 R-XTR-9733969 https://reactome.org/PathwayBrowser/#/R-XTR-9733969 Bile salts dissociate from FABP6 IEA Xenopus tropicalis 29746 R-XTR-9733973 https://reactome.org/PathwayBrowser/#/R-XTR-9733973 Bile salts bind FABP6 IEA Xenopus tropicalis 29747 R-BTA-159425 https://reactome.org/PathwayBrowser/#/R-BTA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 29747 R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 29747 R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 29747 R-BTA-192430 https://reactome.org/PathwayBrowser/#/R-BTA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 29747 R-BTA-193385 https://reactome.org/PathwayBrowser/#/R-BTA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Bos taurus 29747 R-BTA-194121 https://reactome.org/PathwayBrowser/#/R-BTA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Bos taurus 29747 R-BTA-194130 https://reactome.org/PathwayBrowser/#/R-BTA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Bos taurus 29747 R-BTA-194153 https://reactome.org/PathwayBrowser/#/R-BTA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Bos taurus 29747 R-BTA-194187 https://reactome.org/PathwayBrowser/#/R-BTA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Bos taurus 29747 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 29747 R-BTA-444654 https://reactome.org/PathwayBrowser/#/R-BTA-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Bos taurus 29747 R-BTA-6803789 https://reactome.org/PathwayBrowser/#/R-BTA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Bos taurus 29747 R-BTA-9733545 https://reactome.org/PathwayBrowser/#/R-BTA-9733545 Bile salts and acids bind ALB IEA Bos taurus 29747 R-BTA-9733960 https://reactome.org/PathwayBrowser/#/R-BTA-9733960 Bile salts and acids dissociate from ALB IEA Bos taurus 29747 R-BTA-9733964 https://reactome.org/PathwayBrowser/#/R-BTA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Bos taurus 29747 R-BTA-9733969 https://reactome.org/PathwayBrowser/#/R-BTA-9733969 Bile salts dissociate from FABP6 IEA Bos taurus 29747 R-BTA-9733973 https://reactome.org/PathwayBrowser/#/R-BTA-9733973 Bile salts bind FABP6 IEA Bos taurus 29747 R-CEL-159425 https://reactome.org/PathwayBrowser/#/R-CEL-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 29747 R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 29747 R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 29747 R-CEL-192430 https://reactome.org/PathwayBrowser/#/R-CEL-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 29747 R-CEL-193385 https://reactome.org/PathwayBrowser/#/R-CEL-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Caenorhabditis elegans 29747 R-CEL-194121 https://reactome.org/PathwayBrowser/#/R-CEL-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29747 R-CEL-194130 https://reactome.org/PathwayBrowser/#/R-CEL-194130 Transport (influx) of bile salts and acids by OATP-A IEA Caenorhabditis elegans 29747 R-CEL-194153 https://reactome.org/PathwayBrowser/#/R-CEL-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Caenorhabditis elegans 29747 R-CEL-194187 https://reactome.org/PathwayBrowser/#/R-CEL-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29747 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 29747 R-CEL-444654 https://reactome.org/PathwayBrowser/#/R-CEL-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Caenorhabditis elegans 29747 R-CEL-6803789 https://reactome.org/PathwayBrowser/#/R-CEL-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Caenorhabditis elegans 29747 R-CEL-9733969 https://reactome.org/PathwayBrowser/#/R-CEL-9733969 Bile salts dissociate from FABP6 IEA Caenorhabditis elegans 29747 R-CEL-9733973 https://reactome.org/PathwayBrowser/#/R-CEL-9733973 Bile salts bind FABP6 IEA Caenorhabditis elegans 29747 R-CFA-159425 https://reactome.org/PathwayBrowser/#/R-CFA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 29747 R-CFA-193385 https://reactome.org/PathwayBrowser/#/R-CFA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Canis familiaris 29747 R-CFA-194121 https://reactome.org/PathwayBrowser/#/R-CFA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Canis familiaris 29747 R-CFA-194130 https://reactome.org/PathwayBrowser/#/R-CFA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Canis familiaris 29747 R-CFA-194153 https://reactome.org/PathwayBrowser/#/R-CFA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Canis familiaris 29747 R-CFA-194187 https://reactome.org/PathwayBrowser/#/R-CFA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Canis familiaris 29747 R-CFA-444654 https://reactome.org/PathwayBrowser/#/R-CFA-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Canis familiaris 29747 R-CFA-6803789 https://reactome.org/PathwayBrowser/#/R-CFA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Canis familiaris 29747 R-CFA-9733545 https://reactome.org/PathwayBrowser/#/R-CFA-9733545 Bile salts and acids bind ALB IEA Canis familiaris 29747 R-CFA-9733960 https://reactome.org/PathwayBrowser/#/R-CFA-9733960 Bile salts and acids dissociate from ALB IEA Canis familiaris 29747 R-CFA-9733964 https://reactome.org/PathwayBrowser/#/R-CFA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Canis familiaris 29747 R-DDI-194153 https://reactome.org/PathwayBrowser/#/R-DDI-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 29747 R-DME-159425 https://reactome.org/PathwayBrowser/#/R-DME-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 29747 R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 29747 R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 29747 R-DME-192430 https://reactome.org/PathwayBrowser/#/R-DME-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 29747 R-DME-194121 https://reactome.org/PathwayBrowser/#/R-DME-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29747 R-DME-194130 https://reactome.org/PathwayBrowser/#/R-DME-194130 Transport (influx) of bile salts and acids by OATP-A IEA Drosophila melanogaster 29747 R-DME-194153 https://reactome.org/PathwayBrowser/#/R-DME-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Drosophila melanogaster 29747 R-DME-194187 https://reactome.org/PathwayBrowser/#/R-DME-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29747 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 29747 R-DME-444654 https://reactome.org/PathwayBrowser/#/R-DME-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Drosophila melanogaster 29747 R-DME-6803789 https://reactome.org/PathwayBrowser/#/R-DME-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Drosophila melanogaster 29747 R-DME-9733969 https://reactome.org/PathwayBrowser/#/R-DME-9733969 Bile salts dissociate from FABP6 IEA Drosophila melanogaster 29747 R-DME-9733973 https://reactome.org/PathwayBrowser/#/R-DME-9733973 Bile salts bind FABP6 IEA Drosophila melanogaster 29747 R-DRE-159425 https://reactome.org/PathwayBrowser/#/R-DRE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 29747 R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 29747 R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 29747 R-DRE-192430 https://reactome.org/PathwayBrowser/#/R-DRE-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 29747 R-DRE-193385 https://reactome.org/PathwayBrowser/#/R-DRE-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Danio rerio 29747 R-DRE-194121 https://reactome.org/PathwayBrowser/#/R-DRE-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Danio rerio 29747 R-DRE-194130 https://reactome.org/PathwayBrowser/#/R-DRE-194130 Transport (influx) of bile salts and acids by OATP-A IEA Danio rerio 29747 R-DRE-194187 https://reactome.org/PathwayBrowser/#/R-DRE-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Danio rerio 29747 R-DRE-6803789 https://reactome.org/PathwayBrowser/#/R-DRE-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Danio rerio 29747 R-DRE-9733969 https://reactome.org/PathwayBrowser/#/R-DRE-9733969 Bile salts dissociate from FABP6 IEA Danio rerio 29747 R-DRE-9733973 https://reactome.org/PathwayBrowser/#/R-DRE-9733973 Bile salts bind FABP6 IEA Danio rerio 29747 R-GGA-159425 https://reactome.org/PathwayBrowser/#/R-GGA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 29747 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 29747 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 29747 R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 29747 R-GGA-193385 https://reactome.org/PathwayBrowser/#/R-GGA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Gallus gallus 29747 R-GGA-194130 https://reactome.org/PathwayBrowser/#/R-GGA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Gallus gallus 29747 R-GGA-194153 https://reactome.org/PathwayBrowser/#/R-GGA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Gallus gallus 29747 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus 29747 R-GGA-6803789 https://reactome.org/PathwayBrowser/#/R-GGA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Gallus gallus 29747 R-GGA-9733545 https://reactome.org/PathwayBrowser/#/R-GGA-9733545 Bile salts and acids bind ALB IEA Gallus gallus 29747 R-GGA-9733960 https://reactome.org/PathwayBrowser/#/R-GGA-9733960 Bile salts and acids dissociate from ALB IEA Gallus gallus 29747 R-GGA-9733964 https://reactome.org/PathwayBrowser/#/R-GGA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Gallus gallus 29747 R-GGA-9733969 https://reactome.org/PathwayBrowser/#/R-GGA-9733969 Bile salts dissociate from FABP6 IEA Gallus gallus 29747 R-GGA-9733973 https://reactome.org/PathwayBrowser/#/R-GGA-9733973 Bile salts bind FABP6 IEA Gallus gallus 29747 R-HSA-159425 https://reactome.org/PathwayBrowser/#/R-HSA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 29747 R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 29747 R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 29747 R-HSA-192430 https://reactome.org/PathwayBrowser/#/R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 29747 R-HSA-193385 https://reactome.org/PathwayBrowser/#/R-HSA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH TAS Homo sapiens 29747 R-HSA-193399 https://reactome.org/PathwayBrowser/#/R-HSA-193399 Cholate is translocated from the peroxisomal matrix to the cytosol TAS Homo sapiens 29747 R-HSA-194121 https://reactome.org/PathwayBrowser/#/R-HSA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol TAS Homo sapiens 29747 R-HSA-194130 https://reactome.org/PathwayBrowser/#/R-HSA-194130 Transport (influx) of bile salts and acids by OATP-A TAS Homo sapiens 29747 R-HSA-194153 https://reactome.org/PathwayBrowser/#/R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region TAS Homo sapiens 29747 R-HSA-194187 https://reactome.org/PathwayBrowser/#/R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol TAS Homo sapiens 29747 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 29747 R-HSA-444654 https://reactome.org/PathwayBrowser/#/R-HSA-444654 G-protein coupled bile acid receptor binds lithocholic acid TAS Homo sapiens 29747 R-HSA-6803789 https://reactome.org/PathwayBrowser/#/R-HSA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA TAS Homo sapiens 29747 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 29747 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 29747 R-HSA-9733545 https://reactome.org/PathwayBrowser/#/R-HSA-9733545 Bile salts and acids bind ALB TAS Homo sapiens 29747 R-HSA-9733960 https://reactome.org/PathwayBrowser/#/R-HSA-9733960 Bile salts and acids dissociate from ALB TAS Homo sapiens 29747 R-HSA-9733964 https://reactome.org/PathwayBrowser/#/R-HSA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region TAS Homo sapiens 29747 R-HSA-9733969 https://reactome.org/PathwayBrowser/#/R-HSA-9733969 Bile salts dissociate from FABP6 TAS Homo sapiens 29747 R-HSA-9733973 https://reactome.org/PathwayBrowser/#/R-HSA-9733973 Bile salts bind FABP6 TAS Homo sapiens 29747 R-MMU-159425 https://reactome.org/PathwayBrowser/#/R-MMU-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 29747 R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 29747 R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 29747 R-MMU-192430 https://reactome.org/PathwayBrowser/#/R-MMU-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 29747 R-MMU-193385 https://reactome.org/PathwayBrowser/#/R-MMU-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Mus musculus 29747 R-MMU-194121 https://reactome.org/PathwayBrowser/#/R-MMU-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Mus musculus 29747 R-MMU-194130 https://reactome.org/PathwayBrowser/#/R-MMU-194130 Transport (influx) of bile salts and acids by OATP-A IEA Mus musculus 29747 R-MMU-194153 https://reactome.org/PathwayBrowser/#/R-MMU-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Mus musculus 29747 R-MMU-194187 https://reactome.org/PathwayBrowser/#/R-MMU-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Mus musculus 29747 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 29747 R-MMU-444654 https://reactome.org/PathwayBrowser/#/R-MMU-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Mus musculus 29747 R-MMU-6803789 https://reactome.org/PathwayBrowser/#/R-MMU-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Mus musculus 29747 R-MMU-9733545 https://reactome.org/PathwayBrowser/#/R-MMU-9733545 Bile salts and acids bind ALB IEA Mus musculus 29747 R-MMU-9733960 https://reactome.org/PathwayBrowser/#/R-MMU-9733960 Bile salts and acids dissociate from ALB IEA Mus musculus 29747 R-MMU-9733964 https://reactome.org/PathwayBrowser/#/R-MMU-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Mus musculus 29747 R-MMU-9733969 https://reactome.org/PathwayBrowser/#/R-MMU-9733969 Bile salts dissociate from FABP6 IEA Mus musculus 29747 R-MMU-9733973 https://reactome.org/PathwayBrowser/#/R-MMU-9733973 Bile salts bind FABP6 IEA Mus musculus 29747 R-RNO-159425 https://reactome.org/PathwayBrowser/#/R-RNO-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 29747 R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 29747 R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 29747 R-RNO-192430 https://reactome.org/PathwayBrowser/#/R-RNO-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 29747 R-RNO-193385 https://reactome.org/PathwayBrowser/#/R-RNO-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Rattus norvegicus 29747 R-RNO-194121 https://reactome.org/PathwayBrowser/#/R-RNO-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Rattus norvegicus 29747 R-RNO-194130 https://reactome.org/PathwayBrowser/#/R-RNO-194130 Transport (influx) of bile salts and acids by OATP-A IEA Rattus norvegicus 29747 R-RNO-194153 https://reactome.org/PathwayBrowser/#/R-RNO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 29747 R-RNO-194187 https://reactome.org/PathwayBrowser/#/R-RNO-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Rattus norvegicus 29747 R-RNO-444654 https://reactome.org/PathwayBrowser/#/R-RNO-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Rattus norvegicus 29747 R-RNO-6803789 https://reactome.org/PathwayBrowser/#/R-RNO-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Rattus norvegicus 29747 R-RNO-9733545 https://reactome.org/PathwayBrowser/#/R-RNO-9733545 Bile salts and acids bind ALB IEA Rattus norvegicus 29747 R-RNO-9733960 https://reactome.org/PathwayBrowser/#/R-RNO-9733960 Bile salts and acids dissociate from ALB IEA Rattus norvegicus 29747 R-RNO-9733964 https://reactome.org/PathwayBrowser/#/R-RNO-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 29747 R-RNO-9733969 https://reactome.org/PathwayBrowser/#/R-RNO-9733969 Bile salts dissociate from FABP6 IEA Rattus norvegicus 29747 R-RNO-9733973 https://reactome.org/PathwayBrowser/#/R-RNO-9733973 Bile salts bind FABP6 IEA Rattus norvegicus 29747 R-SCE-159425 https://reactome.org/PathwayBrowser/#/R-SCE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 29747 R-SCE-193385 https://reactome.org/PathwayBrowser/#/R-SCE-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Saccharomyces cerevisiae 29747 R-SCE-194153 https://reactome.org/PathwayBrowser/#/R-SCE-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Saccharomyces cerevisiae 29747 R-SPO-194153 https://reactome.org/PathwayBrowser/#/R-SPO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 29747 R-SSC-159425 https://reactome.org/PathwayBrowser/#/R-SSC-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 29747 R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 29747 R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 29747 R-SSC-192430 https://reactome.org/PathwayBrowser/#/R-SSC-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 29747 R-SSC-193385 https://reactome.org/PathwayBrowser/#/R-SSC-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Sus scrofa 29747 R-SSC-194121 https://reactome.org/PathwayBrowser/#/R-SSC-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Sus scrofa 29747 R-SSC-194130 https://reactome.org/PathwayBrowser/#/R-SSC-194130 Transport (influx) of bile salts and acids by OATP-A IEA Sus scrofa 29747 R-SSC-194153 https://reactome.org/PathwayBrowser/#/R-SSC-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Sus scrofa 29747 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa 29747 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 29747 R-SSC-444654 https://reactome.org/PathwayBrowser/#/R-SSC-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Sus scrofa 29747 R-SSC-6803789 https://reactome.org/PathwayBrowser/#/R-SSC-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Sus scrofa 29747 R-SSC-9733545 https://reactome.org/PathwayBrowser/#/R-SSC-9733545 Bile salts and acids bind ALB IEA Sus scrofa 29747 R-SSC-9733960 https://reactome.org/PathwayBrowser/#/R-SSC-9733960 Bile salts and acids dissociate from ALB IEA Sus scrofa 29747 R-SSC-9733964 https://reactome.org/PathwayBrowser/#/R-SSC-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Sus scrofa 29747 R-SSC-9733969 https://reactome.org/PathwayBrowser/#/R-SSC-9733969 Bile salts dissociate from FABP6 IEA Sus scrofa 29747 R-SSC-9733973 https://reactome.org/PathwayBrowser/#/R-SSC-9733973 Bile salts bind FABP6 IEA Sus scrofa 29747 R-XTR-159425 https://reactome.org/PathwayBrowser/#/R-XTR-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 29747 R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 29747 R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 29747 R-XTR-192430 https://reactome.org/PathwayBrowser/#/R-XTR-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 29747 R-XTR-193385 https://reactome.org/PathwayBrowser/#/R-XTR-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Xenopus tropicalis 29747 R-XTR-194121 https://reactome.org/PathwayBrowser/#/R-XTR-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29747 R-XTR-194153 https://reactome.org/PathwayBrowser/#/R-XTR-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 29747 R-XTR-194187 https://reactome.org/PathwayBrowser/#/R-XTR-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29747 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 29747 R-XTR-444654 https://reactome.org/PathwayBrowser/#/R-XTR-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Xenopus tropicalis 29747 R-XTR-6803789 https://reactome.org/PathwayBrowser/#/R-XTR-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Xenopus tropicalis 29747 R-XTR-9733545 https://reactome.org/PathwayBrowser/#/R-XTR-9733545 Bile salts and acids bind ALB IEA Xenopus tropicalis 29747 R-XTR-9733960 https://reactome.org/PathwayBrowser/#/R-XTR-9733960 Bile salts and acids dissociate from ALB IEA Xenopus tropicalis 29747 R-XTR-9733964 https://reactome.org/PathwayBrowser/#/R-XTR-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 29747 R-XTR-9733969 https://reactome.org/PathwayBrowser/#/R-XTR-9733969 Bile salts dissociate from FABP6 IEA Xenopus tropicalis 29747 R-XTR-9733973 https://reactome.org/PathwayBrowser/#/R-XTR-9733973 Bile salts bind FABP6 IEA Xenopus tropicalis 29750 R-BTA-893593 https://reactome.org/PathwayBrowser/#/R-BTA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Bos taurus 29750 R-CEL-893593 https://reactome.org/PathwayBrowser/#/R-CEL-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Caenorhabditis elegans 29750 R-CFA-893593 https://reactome.org/PathwayBrowser/#/R-CFA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Canis familiaris 29750 R-DDI-893593 https://reactome.org/PathwayBrowser/#/R-DDI-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Dictyostelium discoideum 29750 R-DME-893593 https://reactome.org/PathwayBrowser/#/R-DME-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Drosophila melanogaster 29750 R-DRE-893593 https://reactome.org/PathwayBrowser/#/R-DRE-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Danio rerio 29750 R-GGA-893593 https://reactome.org/PathwayBrowser/#/R-GGA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Gallus gallus 29750 R-HSA-893593 https://reactome.org/PathwayBrowser/#/R-HSA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine TAS Homo sapiens 29750 R-MMU-893593 https://reactome.org/PathwayBrowser/#/R-MMU-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Mus musculus 29750 R-RNO-893593 https://reactome.org/PathwayBrowser/#/R-RNO-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Rattus norvegicus 29750 R-SCE-893593 https://reactome.org/PathwayBrowser/#/R-SCE-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Saccharomyces cerevisiae 29750 R-SPO-893593 https://reactome.org/PathwayBrowser/#/R-SPO-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Schizosaccharomyces pombe 29750 R-SSC-893593 https://reactome.org/PathwayBrowser/#/R-SSC-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Sus scrofa 29750 R-XTR-893593 https://reactome.org/PathwayBrowser/#/R-XTR-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Xenopus tropicalis 29788 R-BTA-9854368 https://reactome.org/PathwayBrowser/#/R-BTA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Bos taurus 29788 R-CEL-9854368 https://reactome.org/PathwayBrowser/#/R-CEL-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Caenorhabditis elegans 29788 R-CFA-9854368 https://reactome.org/PathwayBrowser/#/R-CFA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Canis familiaris 29788 R-DDI-9854368 https://reactome.org/PathwayBrowser/#/R-DDI-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Dictyostelium discoideum 29788 R-DME-9854368 https://reactome.org/PathwayBrowser/#/R-DME-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Drosophila melanogaster 29788 R-DRE-9854368 https://reactome.org/PathwayBrowser/#/R-DRE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Danio rerio 29788 R-GGA-9854368 https://reactome.org/PathwayBrowser/#/R-GGA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Gallus gallus 29788 R-HSA-9854368 https://reactome.org/PathwayBrowser/#/R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S TAS Homo sapiens 29788 R-MMU-9854368 https://reactome.org/PathwayBrowser/#/R-MMU-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Mus musculus 29788 R-RNO-9854368 https://reactome.org/PathwayBrowser/#/R-RNO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Rattus norvegicus 29788 R-SCE-9854368 https://reactome.org/PathwayBrowser/#/R-SCE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Saccharomyces cerevisiae 29788 R-SPO-9854368 https://reactome.org/PathwayBrowser/#/R-SPO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Schizosaccharomyces pombe 29788 R-SSC-9854368 https://reactome.org/PathwayBrowser/#/R-SSC-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Sus scrofa 29788 R-XTR-9854368 https://reactome.org/PathwayBrowser/#/R-XTR-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Xenopus tropicalis 2979 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 2979 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 2979 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 2979 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 2979 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 2979 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 2979 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 2979 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 29799 R-HSA-6803978 https://reactome.org/PathwayBrowser/#/R-HSA-6803978 S-nitrosylation of cysteine residues in proteins by N2O3 TAS Homo sapiens 29799 R-HSA-6803988 https://reactome.org/PathwayBrowser/#/R-HSA-6803988 N2O3 enters bacteria TAS Homo sapiens 29799 R-HSA-6803999 https://reactome.org/PathwayBrowser/#/R-HSA-6803999 HNO2 produces N2O3 TAS Homo sapiens 29799 R-HSA-6804006 https://reactome.org/PathwayBrowser/#/R-HSA-6804006 NO and NO2 react to N2O3 TAS Homo sapiens 29799 R-HSA-6804035 https://reactome.org/PathwayBrowser/#/R-HSA-6804035 N2O3 diffuses to phagosome TAS Homo sapiens 29805 R-BTA-389826 https://reactome.org/PathwayBrowser/#/R-BTA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Bos taurus 29805 R-BTA-389842 https://reactome.org/PathwayBrowser/#/R-BTA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Bos taurus 29805 R-CEL-389842 https://reactome.org/PathwayBrowser/#/R-CEL-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Caenorhabditis elegans 29805 R-CFA-389826 https://reactome.org/PathwayBrowser/#/R-CFA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Canis familiaris 29805 R-CFA-389842 https://reactome.org/PathwayBrowser/#/R-CFA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Canis familiaris 29805 R-DDI-389842 https://reactome.org/PathwayBrowser/#/R-DDI-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Dictyostelium discoideum 29805 R-DME-389826 https://reactome.org/PathwayBrowser/#/R-DME-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Drosophila melanogaster 29805 R-DME-389842 https://reactome.org/PathwayBrowser/#/R-DME-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Drosophila melanogaster 29805 R-DRE-389826 https://reactome.org/PathwayBrowser/#/R-DRE-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Danio rerio 29805 R-DRE-389842 https://reactome.org/PathwayBrowser/#/R-DRE-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Danio rerio 29805 R-GGA-389826 https://reactome.org/PathwayBrowser/#/R-GGA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Gallus gallus 29805 R-GGA-389842 https://reactome.org/PathwayBrowser/#/R-GGA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Gallus gallus 29805 R-HSA-389826 https://reactome.org/PathwayBrowser/#/R-HSA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ TAS Homo sapiens 29805 R-HSA-389842 https://reactome.org/PathwayBrowser/#/R-HSA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate TAS Homo sapiens 29805 R-HSA-8953430 https://reactome.org/PathwayBrowser/#/R-HSA-8953430 PXMP2 trimer transports glycolate from cytosol to peroxisomal matrix IEA Homo sapiens 29805 R-MMU-389826 https://reactome.org/PathwayBrowser/#/R-MMU-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Mus musculus 29805 R-MMU-389842 https://reactome.org/PathwayBrowser/#/R-MMU-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Mus musculus 29805 R-MMU-8953429 https://reactome.org/PathwayBrowser/#/R-MMU-8953429 Pxmp2 trimer transports glycolate from cytosol to peroxisomal matrix TAS Mus musculus 29805 R-RNO-389826 https://reactome.org/PathwayBrowser/#/R-RNO-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Rattus norvegicus 29805 R-RNO-389842 https://reactome.org/PathwayBrowser/#/R-RNO-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Rattus norvegicus 29805 R-SSC-389826 https://reactome.org/PathwayBrowser/#/R-SSC-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Sus scrofa 29805 R-SSC-389842 https://reactome.org/PathwayBrowser/#/R-SSC-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Sus scrofa 29805 R-XTR-389826 https://reactome.org/PathwayBrowser/#/R-XTR-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Xenopus tropicalis 29805 R-XTR-389842 https://reactome.org/PathwayBrowser/#/R-XTR-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Xenopus tropicalis 29806 R-BTA-70573 https://reactome.org/PathwayBrowser/#/R-BTA-70573 argininosuccinate <=> fumarate + arginine IEA Bos taurus 29806 R-BTA-70982 https://reactome.org/PathwayBrowser/#/R-BTA-70982 FH tetramer hydrates fumarate to L-malate IEA Bos taurus 29806 R-BTA-70994 https://reactome.org/PathwayBrowser/#/R-BTA-70994 SDH complex dehydrogenates succinate IEA Bos taurus 29806 R-BTA-71181 https://reactome.org/PathwayBrowser/#/R-BTA-71181 FAH cleaves 4FAA IEA Bos taurus 29806 R-BTA-73800 https://reactome.org/PathwayBrowser/#/R-BTA-73800 SAICAR => AICAR + Fumarate IEA Bos taurus 29806 R-BTA-73828 https://reactome.org/PathwayBrowser/#/R-BTA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Bos taurus 29806 R-BTA-9012268 https://reactome.org/PathwayBrowser/#/R-BTA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Bos taurus 29806 R-BTA-9854672 https://reactome.org/PathwayBrowser/#/R-BTA-9854672 FAD attaches to SDHA IEA Bos taurus 29806 R-CEL-70982 https://reactome.org/PathwayBrowser/#/R-CEL-70982 FH tetramer hydrates fumarate to L-malate IEA Caenorhabditis elegans 29806 R-CEL-70994 https://reactome.org/PathwayBrowser/#/R-CEL-70994 SDH complex dehydrogenates succinate IEA Caenorhabditis elegans 29806 R-CEL-71181 https://reactome.org/PathwayBrowser/#/R-CEL-71181 FAH cleaves 4FAA IEA Caenorhabditis elegans 29806 R-CEL-73800 https://reactome.org/PathwayBrowser/#/R-CEL-73800 SAICAR => AICAR + Fumarate IEA Caenorhabditis elegans 29806 R-CEL-73828 https://reactome.org/PathwayBrowser/#/R-CEL-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Caenorhabditis elegans 29806 R-CEL-9012268 https://reactome.org/PathwayBrowser/#/R-CEL-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 29806 R-CEL-9854672 https://reactome.org/PathwayBrowser/#/R-CEL-9854672 FAD attaches to SDHA IEA Caenorhabditis elegans 29806 R-CFA-70573 https://reactome.org/PathwayBrowser/#/R-CFA-70573 argininosuccinate <=> fumarate + arginine IEA Canis familiaris 29806 R-CFA-70982 https://reactome.org/PathwayBrowser/#/R-CFA-70982 FH tetramer hydrates fumarate to L-malate IEA Canis familiaris 29806 R-CFA-70994 https://reactome.org/PathwayBrowser/#/R-CFA-70994 SDH complex dehydrogenates succinate IEA Canis familiaris 29806 R-CFA-71181 https://reactome.org/PathwayBrowser/#/R-CFA-71181 FAH cleaves 4FAA IEA Canis familiaris 29806 R-CFA-73800 https://reactome.org/PathwayBrowser/#/R-CFA-73800 SAICAR => AICAR + Fumarate IEA Canis familiaris 29806 R-CFA-73828 https://reactome.org/PathwayBrowser/#/R-CFA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Canis familiaris 29806 R-CFA-9012268 https://reactome.org/PathwayBrowser/#/R-CFA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Canis familiaris 29806 R-CFA-9854672 https://reactome.org/PathwayBrowser/#/R-CFA-9854672 FAD attaches to SDHA IEA Canis familiaris 29806 R-DDI-70982 https://reactome.org/PathwayBrowser/#/R-DDI-70982 FH tetramer hydrates fumarate to L-malate IEA Dictyostelium discoideum 29806 R-DDI-70994 https://reactome.org/PathwayBrowser/#/R-DDI-70994 SDH complex dehydrogenates succinate IEA Dictyostelium discoideum 29806 R-DDI-71181 https://reactome.org/PathwayBrowser/#/R-DDI-71181 FAH cleaves 4FAA IEA Dictyostelium discoideum 29806 R-DDI-9854672 https://reactome.org/PathwayBrowser/#/R-DDI-9854672 FAD attaches to SDHA IEA Dictyostelium discoideum 29806 R-DME-70573 https://reactome.org/PathwayBrowser/#/R-DME-70573 argininosuccinate <=> fumarate + arginine IEA Drosophila melanogaster 29806 R-DME-70982 https://reactome.org/PathwayBrowser/#/R-DME-70982 FH tetramer hydrates fumarate to L-malate IEA Drosophila melanogaster 29806 R-DME-70994 https://reactome.org/PathwayBrowser/#/R-DME-70994 SDH complex dehydrogenates succinate IEA Drosophila melanogaster 29806 R-DME-71181 https://reactome.org/PathwayBrowser/#/R-DME-71181 FAH cleaves 4FAA IEA Drosophila melanogaster 29806 R-DME-73800 https://reactome.org/PathwayBrowser/#/R-DME-73800 SAICAR => AICAR + Fumarate IEA Drosophila melanogaster 29806 R-DME-73828 https://reactome.org/PathwayBrowser/#/R-DME-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Drosophila melanogaster 29806 R-DME-9012268 https://reactome.org/PathwayBrowser/#/R-DME-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 29806 R-DME-9854672 https://reactome.org/PathwayBrowser/#/R-DME-9854672 FAD attaches to SDHA IEA Drosophila melanogaster 29806 R-DRE-70573 https://reactome.org/PathwayBrowser/#/R-DRE-70573 argininosuccinate <=> fumarate + arginine IEA Danio rerio 29806 R-DRE-70982 https://reactome.org/PathwayBrowser/#/R-DRE-70982 FH tetramer hydrates fumarate to L-malate IEA Danio rerio 29806 R-DRE-70994 https://reactome.org/PathwayBrowser/#/R-DRE-70994 SDH complex dehydrogenates succinate IEA Danio rerio 29806 R-DRE-9012268 https://reactome.org/PathwayBrowser/#/R-DRE-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Danio rerio 29806 R-DRE-9854672 https://reactome.org/PathwayBrowser/#/R-DRE-9854672 FAD attaches to SDHA IEA Danio rerio 29806 R-GGA-187617 https://reactome.org/PathwayBrowser/#/R-GGA-187617 argininosuccinate <=> fumarate + arginine TAS Gallus gallus 29806 R-GGA-373129 https://reactome.org/PathwayBrowser/#/R-GGA-373129 fumarate + FADH2 <=> succinate + FAD IEA Gallus gallus 29806 R-GGA-373141 https://reactome.org/PathwayBrowser/#/R-GGA-373141 malate <=> fumarate + H2O TAS Gallus gallus 29806 R-GGA-373145 https://reactome.org/PathwayBrowser/#/R-GGA-373145 fumarate + H2O <=> malate IEA Gallus gallus 29806 R-GGA-373147 https://reactome.org/PathwayBrowser/#/R-GGA-373147 succinate + FAD <=> fumarate + FADH2 IEA Gallus gallus 29806 R-GGA-419255 https://reactome.org/PathwayBrowser/#/R-GGA-419255 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + fumarate TAS Gallus gallus 29806 R-GGA-421197 https://reactome.org/PathwayBrowser/#/R-GGA-421197 adenylosuccinate => adenosine 5'-monophosphate (AMP) + fumarate IEA Gallus gallus 29806 R-GGA-70573 https://reactome.org/PathwayBrowser/#/R-GGA-70573 argininosuccinate <=> fumarate + arginine IEA Gallus gallus 29806 R-GGA-70982 https://reactome.org/PathwayBrowser/#/R-GGA-70982 FH tetramer hydrates fumarate to L-malate IEA Gallus gallus 29806 R-GGA-70994 https://reactome.org/PathwayBrowser/#/R-GGA-70994 SDH complex dehydrogenates succinate IEA Gallus gallus 29806 R-GGA-71181 https://reactome.org/PathwayBrowser/#/R-GGA-71181 FAH cleaves 4FAA IEA Gallus gallus 29806 R-GGA-73800 https://reactome.org/PathwayBrowser/#/R-GGA-73800 SAICAR => AICAR + Fumarate IEA Gallus gallus 29806 R-GGA-73828 https://reactome.org/PathwayBrowser/#/R-GGA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Gallus gallus 29806 R-GGA-9854672 https://reactome.org/PathwayBrowser/#/R-GGA-9854672 FAD attaches to SDHA IEA Gallus gallus 29806 R-HSA-163213 https://reactome.org/PathwayBrowser/#/R-HSA-163213 Transfer of electrons through the succinate dehydrogenase complex IEA Homo sapiens 29806 R-HSA-70573 https://reactome.org/PathwayBrowser/#/R-HSA-70573 argininosuccinate <=> fumarate + arginine TAS Homo sapiens 29806 R-HSA-70982 https://reactome.org/PathwayBrowser/#/R-HSA-70982 FH tetramer hydrates fumarate to L-malate TAS Homo sapiens 29806 R-HSA-70994 https://reactome.org/PathwayBrowser/#/R-HSA-70994 SDH complex dehydrogenates succinate TAS Homo sapiens 29806 R-HSA-71181 https://reactome.org/PathwayBrowser/#/R-HSA-71181 FAH cleaves 4FAA TAS Homo sapiens 29806 R-HSA-73800 https://reactome.org/PathwayBrowser/#/R-HSA-73800 SAICAR => AICAR + Fumarate TAS Homo sapiens 29806 R-HSA-73828 https://reactome.org/PathwayBrowser/#/R-HSA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate TAS Homo sapiens 29806 R-HSA-9012268 https://reactome.org/PathwayBrowser/#/R-HSA-9012268 ME2 tetramer decarboxylates MAL to PYR TAS Homo sapiens 29806 R-HSA-9854672 https://reactome.org/PathwayBrowser/#/R-HSA-9854672 FAD attaches to SDHA TAS Homo sapiens 29806 R-MMU-70573 https://reactome.org/PathwayBrowser/#/R-MMU-70573 argininosuccinate <=> fumarate + arginine IEA Mus musculus 29806 R-MMU-70982 https://reactome.org/PathwayBrowser/#/R-MMU-70982 FH tetramer hydrates fumarate to L-malate IEA Mus musculus 29806 R-MMU-70994 https://reactome.org/PathwayBrowser/#/R-MMU-70994 SDH complex dehydrogenates succinate IEA Mus musculus 29806 R-MMU-71181 https://reactome.org/PathwayBrowser/#/R-MMU-71181 FAH cleaves 4FAA IEA Mus musculus 29806 R-MMU-73800 https://reactome.org/PathwayBrowser/#/R-MMU-73800 SAICAR => AICAR + Fumarate IEA Mus musculus 29806 R-MMU-73828 https://reactome.org/PathwayBrowser/#/R-MMU-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Mus musculus 29806 R-MMU-9012268 https://reactome.org/PathwayBrowser/#/R-MMU-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Mus musculus 29806 R-MMU-9854672 https://reactome.org/PathwayBrowser/#/R-MMU-9854672 FAD attaches to SDHA IEA Mus musculus 29806 R-RNO-70573 https://reactome.org/PathwayBrowser/#/R-RNO-70573 argininosuccinate <=> fumarate + arginine IEA Rattus norvegicus 29806 R-RNO-70982 https://reactome.org/PathwayBrowser/#/R-RNO-70982 FH tetramer hydrates fumarate to L-malate IEA Rattus norvegicus 29806 R-RNO-70994 https://reactome.org/PathwayBrowser/#/R-RNO-70994 SDH complex dehydrogenates succinate IEA Rattus norvegicus 29806 R-RNO-71181 https://reactome.org/PathwayBrowser/#/R-RNO-71181 FAH cleaves 4FAA IEA Rattus norvegicus 29806 R-RNO-73800 https://reactome.org/PathwayBrowser/#/R-RNO-73800 SAICAR => AICAR + Fumarate IEA Rattus norvegicus 29806 R-RNO-73828 https://reactome.org/PathwayBrowser/#/R-RNO-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Rattus norvegicus 29806 R-RNO-9012268 https://reactome.org/PathwayBrowser/#/R-RNO-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 29806 R-RNO-9854672 https://reactome.org/PathwayBrowser/#/R-RNO-9854672 FAD attaches to SDHA IEA Rattus norvegicus 29806 R-SCE-70573 https://reactome.org/PathwayBrowser/#/R-SCE-70573 argininosuccinate <=> fumarate + arginine IEA Saccharomyces cerevisiae 29806 R-SCE-70982 https://reactome.org/PathwayBrowser/#/R-SCE-70982 FH tetramer hydrates fumarate to L-malate IEA Saccharomyces cerevisiae 29806 R-SCE-70994 https://reactome.org/PathwayBrowser/#/R-SCE-70994 SDH complex dehydrogenates succinate IEA Saccharomyces cerevisiae 29806 R-SCE-73800 https://reactome.org/PathwayBrowser/#/R-SCE-73800 SAICAR => AICAR + Fumarate IEA Saccharomyces cerevisiae 29806 R-SCE-73828 https://reactome.org/PathwayBrowser/#/R-SCE-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Saccharomyces cerevisiae 29806 R-SCE-9854672 https://reactome.org/PathwayBrowser/#/R-SCE-9854672 FAD attaches to SDHA IEA Saccharomyces cerevisiae 29806 R-SPO-70573 https://reactome.org/PathwayBrowser/#/R-SPO-70573 argininosuccinate <=> fumarate + arginine IEA Schizosaccharomyces pombe 29806 R-SPO-70982 https://reactome.org/PathwayBrowser/#/R-SPO-70982 FH tetramer hydrates fumarate to L-malate IEA Schizosaccharomyces pombe 29806 R-SPO-70994 https://reactome.org/PathwayBrowser/#/R-SPO-70994 SDH complex dehydrogenates succinate IEA Schizosaccharomyces pombe 29806 R-SPO-73800 https://reactome.org/PathwayBrowser/#/R-SPO-73800 SAICAR => AICAR + Fumarate IEA Schizosaccharomyces pombe 29806 R-SPO-73828 https://reactome.org/PathwayBrowser/#/R-SPO-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Schizosaccharomyces pombe 29806 R-SPO-9854672 https://reactome.org/PathwayBrowser/#/R-SPO-9854672 FAD attaches to SDHA IEA Schizosaccharomyces pombe 29806 R-SSC-70573 https://reactome.org/PathwayBrowser/#/R-SSC-70573 argininosuccinate <=> fumarate + arginine IEA Sus scrofa 29806 R-SSC-70982 https://reactome.org/PathwayBrowser/#/R-SSC-70982 FH tetramer hydrates fumarate to L-malate IEA Sus scrofa 29806 R-SSC-70994 https://reactome.org/PathwayBrowser/#/R-SSC-70994 SDH complex dehydrogenates succinate IEA Sus scrofa 29806 R-SSC-71181 https://reactome.org/PathwayBrowser/#/R-SSC-71181 FAH cleaves 4FAA IEA Sus scrofa 29806 R-SSC-73800 https://reactome.org/PathwayBrowser/#/R-SSC-73800 SAICAR => AICAR + Fumarate IEA Sus scrofa 29806 R-SSC-73828 https://reactome.org/PathwayBrowser/#/R-SSC-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Sus scrofa 29806 R-SSC-9012268 https://reactome.org/PathwayBrowser/#/R-SSC-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Sus scrofa 29806 R-SSC-9854672 https://reactome.org/PathwayBrowser/#/R-SSC-9854672 FAD attaches to SDHA IEA Sus scrofa 29806 R-XTR-70573 https://reactome.org/PathwayBrowser/#/R-XTR-70573 argininosuccinate <=> fumarate + arginine IEA Xenopus tropicalis 29806 R-XTR-70994 https://reactome.org/PathwayBrowser/#/R-XTR-70994 SDH complex dehydrogenates succinate IEA Xenopus tropicalis 29806 R-XTR-71181 https://reactome.org/PathwayBrowser/#/R-XTR-71181 FAH cleaves 4FAA IEA Xenopus tropicalis 29806 R-XTR-73800 https://reactome.org/PathwayBrowser/#/R-XTR-73800 SAICAR => AICAR + Fumarate IEA Xenopus tropicalis 29806 R-XTR-73828 https://reactome.org/PathwayBrowser/#/R-XTR-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Xenopus tropicalis 29806 R-XTR-9012268 https://reactome.org/PathwayBrowser/#/R-XTR-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 29806 R-XTR-9854672 https://reactome.org/PathwayBrowser/#/R-XTR-9854672 FAD attaches to SDHA IEA Xenopus tropicalis 2981 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 2981 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 2981 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 2981 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 2981 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 2981 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 2981 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 2981 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 29919 R-AMA-1614571 https://reactome.org/PathwayBrowser/#/R-AMA-1614571 Sqr oxidizes sulfide to bound persulfide TAS Arenicola marina 29919 R-BTA-1614362 https://reactome.org/PathwayBrowser/#/R-BTA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Bos taurus 29919 R-BTA-1614567 https://reactome.org/PathwayBrowser/#/R-BTA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Bos taurus 29919 R-BTA-1614591 https://reactome.org/PathwayBrowser/#/R-BTA-1614591 Excess cysteine yields lanthionine and H2S IEA Bos taurus 29919 R-BTA-1614614 https://reactome.org/PathwayBrowser/#/R-BTA-1614614 Cysteine is degraded to serine and H2S IEA Bos taurus 29919 R-BTA-1614631 https://reactome.org/PathwayBrowser/#/R-BTA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Bos taurus 29919 R-BTA-1655879 https://reactome.org/PathwayBrowser/#/R-BTA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Bos taurus 29919 R-BTA-6793591 https://reactome.org/PathwayBrowser/#/R-BTA-6793591 LIAS synthesizes lipoyl-GCSH IEA Bos taurus 29919 R-BTA-9035484 https://reactome.org/PathwayBrowser/#/R-BTA-9035484 CysS248-MPST:TXN2 dissociates IEA Bos taurus 29919 R-CEL-1614567 https://reactome.org/PathwayBrowser/#/R-CEL-1614567 Excess homocysteine yields homolanthionine and H2S IEA Caenorhabditis elegans 29919 R-CEL-1614591 https://reactome.org/PathwayBrowser/#/R-CEL-1614591 Excess cysteine yields lanthionine and H2S IEA Caenorhabditis elegans 29919 R-CEL-1614614 https://reactome.org/PathwayBrowser/#/R-CEL-1614614 Cysteine is degraded to serine and H2S IEA Caenorhabditis elegans 29919 R-CEL-1614631 https://reactome.org/PathwayBrowser/#/R-CEL-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Caenorhabditis elegans 29919 R-CEL-9035484 https://reactome.org/PathwayBrowser/#/R-CEL-9035484 CysS248-MPST:TXN2 dissociates IEA Caenorhabditis elegans 29919 R-CFA-1614362 https://reactome.org/PathwayBrowser/#/R-CFA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Canis familiaris 29919 R-CFA-1614567 https://reactome.org/PathwayBrowser/#/R-CFA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Canis familiaris 29919 R-CFA-1614591 https://reactome.org/PathwayBrowser/#/R-CFA-1614591 Excess cysteine yields lanthionine and H2S IEA Canis familiaris 29919 R-CFA-1614614 https://reactome.org/PathwayBrowser/#/R-CFA-1614614 Cysteine is degraded to serine and H2S IEA Canis familiaris 29919 R-CFA-1614631 https://reactome.org/PathwayBrowser/#/R-CFA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Canis familiaris 29919 R-CFA-1655879 https://reactome.org/PathwayBrowser/#/R-CFA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Canis familiaris 29919 R-CFA-6793591 https://reactome.org/PathwayBrowser/#/R-CFA-6793591 LIAS synthesizes lipoyl-GCSH IEA Canis familiaris 29919 R-DDI-1614567 https://reactome.org/PathwayBrowser/#/R-DDI-1614567 Excess homocysteine yields homolanthionine and H2S IEA Dictyostelium discoideum 29919 R-DDI-1614591 https://reactome.org/PathwayBrowser/#/R-DDI-1614591 Excess cysteine yields lanthionine and H2S IEA Dictyostelium discoideum 29919 R-DDI-1614614 https://reactome.org/PathwayBrowser/#/R-DDI-1614614 Cysteine is degraded to serine and H2S IEA Dictyostelium discoideum 29919 R-DDI-1614631 https://reactome.org/PathwayBrowser/#/R-DDI-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Dictyostelium discoideum 29919 R-DDI-9035484 https://reactome.org/PathwayBrowser/#/R-DDI-9035484 CysS248-MPST:TXN2 dissociates IEA Dictyostelium discoideum 29919 R-DME-1614567 https://reactome.org/PathwayBrowser/#/R-DME-1614567 Excess homocysteine yields homolanthionine and H2S IEA Drosophila melanogaster 29919 R-DME-1614591 https://reactome.org/PathwayBrowser/#/R-DME-1614591 Excess cysteine yields lanthionine and H2S IEA Drosophila melanogaster 29919 R-DME-1614614 https://reactome.org/PathwayBrowser/#/R-DME-1614614 Cysteine is degraded to serine and H2S IEA Drosophila melanogaster 29919 R-DME-1614631 https://reactome.org/PathwayBrowser/#/R-DME-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Drosophila melanogaster 29919 R-DME-6793591 https://reactome.org/PathwayBrowser/#/R-DME-6793591 LIAS synthesizes lipoyl-GCSH IEA Drosophila melanogaster 29919 R-DRE-1614567 https://reactome.org/PathwayBrowser/#/R-DRE-1614567 Excess homocysteine yields homolanthionine and H2S IEA Danio rerio 29919 R-DRE-1614591 https://reactome.org/PathwayBrowser/#/R-DRE-1614591 Excess cysteine yields lanthionine and H2S IEA Danio rerio 29919 R-DRE-1614614 https://reactome.org/PathwayBrowser/#/R-DRE-1614614 Cysteine is degraded to serine and H2S IEA Danio rerio 29919 R-DRE-1614631 https://reactome.org/PathwayBrowser/#/R-DRE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Danio rerio 29919 R-DRE-6793591 https://reactome.org/PathwayBrowser/#/R-DRE-6793591 LIAS synthesizes lipoyl-GCSH IEA Danio rerio 29919 R-DRE-9035484 https://reactome.org/PathwayBrowser/#/R-DRE-9035484 CysS248-MPST:TXN2 dissociates IEA Danio rerio 29919 R-GGA-1614362 https://reactome.org/PathwayBrowser/#/R-GGA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Gallus gallus 29919 R-GGA-1614567 https://reactome.org/PathwayBrowser/#/R-GGA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Gallus gallus 29919 R-GGA-1614591 https://reactome.org/PathwayBrowser/#/R-GGA-1614591 Excess cysteine yields lanthionine and H2S IEA Gallus gallus 29919 R-GGA-1614614 https://reactome.org/PathwayBrowser/#/R-GGA-1614614 Cysteine is degraded to serine and H2S IEA Gallus gallus 29919 R-GGA-1614631 https://reactome.org/PathwayBrowser/#/R-GGA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Gallus gallus 29919 R-GGA-6793591 https://reactome.org/PathwayBrowser/#/R-GGA-6793591 LIAS synthesizes lipoyl-GCSH IEA Gallus gallus 29919 R-GGA-9035484 https://reactome.org/PathwayBrowser/#/R-GGA-9035484 CysS248-MPST:TXN2 dissociates IEA Gallus gallus 29919 R-HSA-1614362 https://reactome.org/PathwayBrowser/#/R-HSA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases TAS Homo sapiens 29919 R-HSA-1614567 https://reactome.org/PathwayBrowser/#/R-HSA-1614567 Excess homocysteine yields homolanthionine and H2S TAS Homo sapiens 29919 R-HSA-1614591 https://reactome.org/PathwayBrowser/#/R-HSA-1614591 Excess cysteine yields lanthionine and H2S TAS Homo sapiens 29919 R-HSA-1614614 https://reactome.org/PathwayBrowser/#/R-HSA-1614614 Cysteine is degraded to serine and H2S TAS Homo sapiens 29919 R-HSA-1614631 https://reactome.org/PathwayBrowser/#/R-HSA-1614631 Homocysteine is degraded to oxobutanoate and H2S TAS Homo sapiens 29919 R-HSA-1614665 https://reactome.org/PathwayBrowser/#/R-HSA-1614665 SQR oxidizes sulfide to bound persulfide IEA Homo sapiens 29919 R-HSA-1655879 https://reactome.org/PathwayBrowser/#/R-HSA-1655879 Thiosulfate can transfer its sulfur atom to glutathione TAS Homo sapiens 29919 R-HSA-6793591 https://reactome.org/PathwayBrowser/#/R-HSA-6793591 LIAS synthesizes lipoyl-GCSH TAS Homo sapiens 29919 R-HSA-9035484 https://reactome.org/PathwayBrowser/#/R-HSA-9035484 CysS248-MPST:TXN2 dissociates TAS Homo sapiens 29919 R-MMU-1614362 https://reactome.org/PathwayBrowser/#/R-MMU-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Mus musculus 29919 R-MMU-1614567 https://reactome.org/PathwayBrowser/#/R-MMU-1614567 Excess homocysteine yields homolanthionine and H2S IEA Mus musculus 29919 R-MMU-1614591 https://reactome.org/PathwayBrowser/#/R-MMU-1614591 Excess cysteine yields lanthionine and H2S IEA Mus musculus 29919 R-MMU-1614614 https://reactome.org/PathwayBrowser/#/R-MMU-1614614 Cysteine is degraded to serine and H2S IEA Mus musculus 29919 R-MMU-1614631 https://reactome.org/PathwayBrowser/#/R-MMU-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Mus musculus 29919 R-MMU-1655879 https://reactome.org/PathwayBrowser/#/R-MMU-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Mus musculus 29919 R-MMU-6793591 https://reactome.org/PathwayBrowser/#/R-MMU-6793591 LIAS synthesizes lipoyl-GCSH IEA Mus musculus 29919 R-MMU-9035484 https://reactome.org/PathwayBrowser/#/R-MMU-9035484 CysS248-MPST:TXN2 dissociates IEA Mus musculus 29919 R-RNO-1614362 https://reactome.org/PathwayBrowser/#/R-RNO-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Rattus norvegicus 29919 R-RNO-1614567 https://reactome.org/PathwayBrowser/#/R-RNO-1614567 Excess homocysteine yields homolanthionine and H2S IEA Rattus norvegicus 29919 R-RNO-1614591 https://reactome.org/PathwayBrowser/#/R-RNO-1614591 Excess cysteine yields lanthionine and H2S IEA Rattus norvegicus 29919 R-RNO-1614614 https://reactome.org/PathwayBrowser/#/R-RNO-1614614 Cysteine is degraded to serine and H2S IEA Rattus norvegicus 29919 R-RNO-1614631 https://reactome.org/PathwayBrowser/#/R-RNO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Rattus norvegicus 29919 R-RNO-1655879 https://reactome.org/PathwayBrowser/#/R-RNO-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Rattus norvegicus 29919 R-RNO-6793591 https://reactome.org/PathwayBrowser/#/R-RNO-6793591 LIAS synthesizes lipoyl-GCSH IEA Rattus norvegicus 29919 R-RNO-9035484 https://reactome.org/PathwayBrowser/#/R-RNO-9035484 CysS248-MPST:TXN2 dissociates IEA Rattus norvegicus 29919 R-SCE-1614567 https://reactome.org/PathwayBrowser/#/R-SCE-1614567 Excess homocysteine yields homolanthionine and H2S IEA Saccharomyces cerevisiae 29919 R-SCE-1614591 https://reactome.org/PathwayBrowser/#/R-SCE-1614591 Excess cysteine yields lanthionine and H2S IEA Saccharomyces cerevisiae 29919 R-SCE-1614614 https://reactome.org/PathwayBrowser/#/R-SCE-1614614 Cysteine is degraded to serine and H2S IEA Saccharomyces cerevisiae 29919 R-SCE-1614631 https://reactome.org/PathwayBrowser/#/R-SCE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Saccharomyces cerevisiae 29919 R-SPO-1614567 https://reactome.org/PathwayBrowser/#/R-SPO-1614567 Excess homocysteine yields homolanthionine and H2S IEA Schizosaccharomyces pombe 29919 R-SPO-1614591 https://reactome.org/PathwayBrowser/#/R-SPO-1614591 Excess cysteine yields lanthionine and H2S IEA Schizosaccharomyces pombe 29919 R-SPO-1614614 https://reactome.org/PathwayBrowser/#/R-SPO-1614614 Cysteine is degraded to serine and H2S IEA Schizosaccharomyces pombe 29919 R-SPO-1614631 https://reactome.org/PathwayBrowser/#/R-SPO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Schizosaccharomyces pombe 29919 R-SSC-1614362 https://reactome.org/PathwayBrowser/#/R-SSC-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Sus scrofa 29919 R-SSC-1614567 https://reactome.org/PathwayBrowser/#/R-SSC-1614567 Excess homocysteine yields homolanthionine and H2S IEA Sus scrofa 29919 R-SSC-1614591 https://reactome.org/PathwayBrowser/#/R-SSC-1614591 Excess cysteine yields lanthionine and H2S IEA Sus scrofa 29919 R-SSC-1614614 https://reactome.org/PathwayBrowser/#/R-SSC-1614614 Cysteine is degraded to serine and H2S IEA Sus scrofa 29919 R-SSC-1614631 https://reactome.org/PathwayBrowser/#/R-SSC-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Sus scrofa 29919 R-SSC-1655879 https://reactome.org/PathwayBrowser/#/R-SSC-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Sus scrofa 29919 R-SSC-6793591 https://reactome.org/PathwayBrowser/#/R-SSC-6793591 LIAS synthesizes lipoyl-GCSH IEA Sus scrofa 29919 R-SSC-9035484 https://reactome.org/PathwayBrowser/#/R-SSC-9035484 CysS248-MPST:TXN2 dissociates IEA Sus scrofa 29919 R-XTR-1614362 https://reactome.org/PathwayBrowser/#/R-XTR-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Xenopus tropicalis 29919 R-XTR-1614567 https://reactome.org/PathwayBrowser/#/R-XTR-1614567 Excess homocysteine yields homolanthionine and H2S IEA Xenopus tropicalis 29919 R-XTR-1614591 https://reactome.org/PathwayBrowser/#/R-XTR-1614591 Excess cysteine yields lanthionine and H2S IEA Xenopus tropicalis 29919 R-XTR-1614614 https://reactome.org/PathwayBrowser/#/R-XTR-1614614 Cysteine is degraded to serine and H2S IEA Xenopus tropicalis 29919 R-XTR-1614631 https://reactome.org/PathwayBrowser/#/R-XTR-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Xenopus tropicalis 29919 R-XTR-1655879 https://reactome.org/PathwayBrowser/#/R-XTR-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Xenopus tropicalis 29919 R-XTR-9035484 https://reactome.org/PathwayBrowser/#/R-XTR-9035484 CysS248-MPST:TXN2 dissociates IEA Xenopus tropicalis 29959 R-BTA-197268 https://reactome.org/PathwayBrowser/#/R-BTA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Bos taurus 29959 R-CFA-197268 https://reactome.org/PathwayBrowser/#/R-CFA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Canis familiaris 29959 R-DDI-197268 https://reactome.org/PathwayBrowser/#/R-DDI-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Dictyostelium discoideum 29959 R-GGA-197268 https://reactome.org/PathwayBrowser/#/R-GGA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Gallus gallus 29959 R-HSA-197187 https://reactome.org/PathwayBrowser/#/R-HSA-197187 ACS transforms to QUIN non-enzymatically TAS Homo sapiens 29959 R-HSA-197268 https://reactome.org/PathwayBrowser/#/R-HSA-197268 QPRT transfers PRIB to QUIN to form NAMN TAS Homo sapiens 29959 R-MMU-197268 https://reactome.org/PathwayBrowser/#/R-MMU-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Mus musculus 29959 R-RNO-197268 https://reactome.org/PathwayBrowser/#/R-RNO-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Rattus norvegicus 29959 R-SCE-197268 https://reactome.org/PathwayBrowser/#/R-SCE-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Saccharomyces cerevisiae 29959 R-SSC-197268 https://reactome.org/PathwayBrowser/#/R-SSC-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Sus scrofa 29959 R-XTR-197268 https://reactome.org/PathwayBrowser/#/R-XTR-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Xenopus tropicalis 29985 R-BTA-1247935 https://reactome.org/PathwayBrowser/#/R-BTA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Bos taurus 29985 R-BTA-174367 https://reactome.org/PathwayBrowser/#/R-BTA-174367 GCL ligates L-Glu to L-Cys IEA Bos taurus 29985 R-BTA-197271 https://reactome.org/PathwayBrowser/#/R-BTA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Bos taurus 29985 R-BTA-197958 https://reactome.org/PathwayBrowser/#/R-BTA-197958 FPGS-2 transforms THF to THFPG IEA Bos taurus 29985 R-BTA-200681 https://reactome.org/PathwayBrowser/#/R-BTA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Bos taurus 29985 R-BTA-200682 https://reactome.org/PathwayBrowser/#/R-BTA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Bos taurus 29985 R-BTA-210404 https://reactome.org/PathwayBrowser/#/R-BTA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Bos taurus 29985 R-BTA-210426 https://reactome.org/PathwayBrowser/#/R-BTA-210426 Glutamate synaptic vesicle docking and priming IEA Bos taurus 29985 R-BTA-210430 https://reactome.org/PathwayBrowser/#/R-BTA-210430 Release of L-Glutamate at the synapse IEA Bos taurus 29985 R-BTA-210439 https://reactome.org/PathwayBrowser/#/R-BTA-210439 glutamate uptake by astrocytes IEA Bos taurus 29985 R-BTA-210444 https://reactome.org/PathwayBrowser/#/R-BTA-210444 L-Glutamate loading of synaptic vesicle IEA Bos taurus 29985 R-BTA-266046 https://reactome.org/PathwayBrowser/#/R-BTA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Bos taurus 29985 R-BTA-372448 https://reactome.org/PathwayBrowser/#/R-BTA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Bos taurus 29985 R-BTA-373075 https://reactome.org/PathwayBrowser/#/R-BTA-373075 Metabotropic glutamate receptors bind glutamate IEA Bos taurus 29985 R-BTA-378513 https://reactome.org/PathwayBrowser/#/R-BTA-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Bos taurus 29985 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 29985 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 29985 R-BTA-399711 https://reactome.org/PathwayBrowser/#/R-BTA-399711 Activation of Ca impermeable AMPA receptors IEA Bos taurus 29985 R-BTA-399712 https://reactome.org/PathwayBrowser/#/R-BTA-399712 Activation of Ca permeable AMPA receptors IEA Bos taurus 29985 R-BTA-420975 https://reactome.org/PathwayBrowser/#/R-BTA-420975 Ca impermeable AMPA receptor ligand binding IEA Bos taurus 29985 R-BTA-420977 https://reactome.org/PathwayBrowser/#/R-BTA-420977 Ca permeable AMPA receptor ligand binding IEA Bos taurus 29985 R-BTA-420980 https://reactome.org/PathwayBrowser/#/R-BTA-420980 Activation of Ca permeable AMPA receptors IEA Bos taurus 29985 R-BTA-428015 https://reactome.org/PathwayBrowser/#/R-BTA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Bos taurus 29985 R-BTA-428052 https://reactome.org/PathwayBrowser/#/R-BTA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Bos taurus 29985 R-BTA-432164 https://reactome.org/PathwayBrowser/#/R-BTA-432164 Ca2+ influx into the post-synaptic cell IEA Bos taurus 29985 R-BTA-438037 https://reactome.org/PathwayBrowser/#/R-BTA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Bos taurus 29985 R-BTA-444705 https://reactome.org/PathwayBrowser/#/R-BTA-444705 T1R1/T1R3 dimer is the umami taste receptor IEA Bos taurus 29985 R-BTA-449715 https://reactome.org/PathwayBrowser/#/R-BTA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Bos taurus 29985 R-BTA-451283 https://reactome.org/PathwayBrowser/#/R-BTA-451283 kainate receptor binds glutamate IEA Bos taurus 29985 R-BTA-451309 https://reactome.org/PathwayBrowser/#/R-BTA-451309 Edited Kainate Receptor binds glutamate IEA Bos taurus 29985 R-BTA-451310 https://reactome.org/PathwayBrowser/#/R-BTA-451310 Activation of Edited Kainate receptors IEA Bos taurus 29985 R-BTA-451311 https://reactome.org/PathwayBrowser/#/R-BTA-451311 Activation of Ca-permeable Kainate receptors IEA Bos taurus 29985 R-BTA-500708 https://reactome.org/PathwayBrowser/#/R-BTA-500708 GRIK3 homomer binds glutamate IEA Bos taurus 29985 R-BTA-500717 https://reactome.org/PathwayBrowser/#/R-BTA-500717 Activation of GRIK3 homomer IEA Bos taurus 29985 R-BTA-504054 https://reactome.org/PathwayBrowser/#/R-BTA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Bos taurus 29985 R-BTA-507749 https://reactome.org/PathwayBrowser/#/R-BTA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Bos taurus 29985 R-BTA-507775 https://reactome.org/PathwayBrowser/#/R-BTA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Bos taurus 29985 R-BTA-508040 https://reactome.org/PathwayBrowser/#/R-BTA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Bos taurus 29985 R-BTA-508179 https://reactome.org/PathwayBrowser/#/R-BTA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Bos taurus 29985 R-BTA-508189 https://reactome.org/PathwayBrowser/#/R-BTA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Bos taurus 29985 R-BTA-508561 https://reactome.org/PathwayBrowser/#/R-BTA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Bos taurus 29985 R-BTA-517444 https://reactome.org/PathwayBrowser/#/R-BTA-517444 TAT aminates HPP IEA Bos taurus 29985 R-BTA-5433072 https://reactome.org/PathwayBrowser/#/R-BTA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Bos taurus 29985 R-BTA-5672965 https://reactome.org/PathwayBrowser/#/R-BTA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Bos taurus 29985 R-BTA-5693783 https://reactome.org/PathwayBrowser/#/R-BTA-5693783 NAALADases hydrolyse NAAG IEA Bos taurus 29985 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 29985 R-BTA-70523 https://reactome.org/PathwayBrowser/#/R-BTA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Bos taurus 29985 R-BTA-70524 https://reactome.org/PathwayBrowser/#/R-BTA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Bos taurus 29985 R-BTA-70542 https://reactome.org/PathwayBrowser/#/R-BTA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Bos taurus 29985 R-BTA-70581 https://reactome.org/PathwayBrowser/#/R-BTA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Bos taurus 29985 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Bos taurus 29985 R-BTA-70592 https://reactome.org/PathwayBrowser/#/R-BTA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Bos taurus 29985 R-BTA-70596 https://reactome.org/PathwayBrowser/#/R-BTA-70596 GOT2 dimer deaminates L-Asp IEA Bos taurus 29985 R-BTA-70599 https://reactome.org/PathwayBrowser/#/R-BTA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Bos taurus 29985 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Bos taurus 29985 R-BTA-70606 https://reactome.org/PathwayBrowser/#/R-BTA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Bos taurus 29985 R-BTA-70609 https://reactome.org/PathwayBrowser/#/R-BTA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Bos taurus 29985 R-BTA-70613 https://reactome.org/PathwayBrowser/#/R-BTA-70613 GOT2 transaminates OA and L-Glu IEA Bos taurus 29985 R-BTA-70654 https://reactome.org/PathwayBrowser/#/R-BTA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Bos taurus 29985 R-BTA-70666 https://reactome.org/PathwayBrowser/#/R-BTA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Bos taurus 29985 R-BTA-70679 https://reactome.org/PathwayBrowser/#/R-BTA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Bos taurus 29985 R-BTA-70723 https://reactome.org/PathwayBrowser/#/R-BTA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Bos taurus 29985 R-BTA-70724 https://reactome.org/PathwayBrowser/#/R-BTA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Bos taurus 29985 R-BTA-70920 https://reactome.org/PathwayBrowser/#/R-BTA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Bos taurus 29985 R-BTA-70940 https://reactome.org/PathwayBrowser/#/R-BTA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Bos taurus 29985 R-BTA-70952 https://reactome.org/PathwayBrowser/#/R-BTA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Bos taurus 29985 R-BTA-71155 https://reactome.org/PathwayBrowser/#/R-BTA-71155 TAT deaminates tyrosine IEA Bos taurus 29985 R-BTA-73577 https://reactome.org/PathwayBrowser/#/R-BTA-73577 CAD hexamer transforms L-Gln to CAP IEA Bos taurus 29985 R-BTA-73647 https://reactome.org/PathwayBrowser/#/R-BTA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Bos taurus 29985 R-BTA-73792 https://reactome.org/PathwayBrowser/#/R-BTA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Bos taurus 29985 R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 29985 R-BTA-73815 https://reactome.org/PathwayBrowser/#/R-BTA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Bos taurus 29985 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 29985 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 29985 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 29985 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 29985 R-BTA-8865774 https://reactome.org/PathwayBrowser/#/R-BTA-8865774 TTLLs polyglutamylate tubulin IEA Bos taurus 29985 R-BTA-8875623 https://reactome.org/PathwayBrowser/#/R-BTA-8875623 SLC25A18,22 import L-Glu, H+ IEA Bos taurus 29985 R-BTA-888572 https://reactome.org/PathwayBrowser/#/R-BTA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Bos taurus 29985 R-BTA-888577 https://reactome.org/PathwayBrowser/#/R-BTA-888577 Synthesis of GABA by GAD2 IEA Bos taurus 29985 R-BTA-893583 https://reactome.org/PathwayBrowser/#/R-BTA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Bos taurus 29985 R-BTA-8942575 https://reactome.org/PathwayBrowser/#/R-BTA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Bos taurus 29985 R-BTA-8943279 https://reactome.org/PathwayBrowser/#/R-BTA-8943279 GGT dimers hydrolyse GSH IEA Bos taurus 29985 R-BTA-916855 https://reactome.org/PathwayBrowser/#/R-BTA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Bos taurus 29985 R-BTA-9717206 https://reactome.org/PathwayBrowser/#/R-BTA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Bos taurus 29985 R-BTA-9748957 https://reactome.org/PathwayBrowser/#/R-BTA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Bos taurus 29985 R-BTA-9753634 https://reactome.org/PathwayBrowser/#/R-BTA-9753634 GGT dimers hydrolyse APAP-SG IEA Bos taurus 29985 R-BTA-977333 https://reactome.org/PathwayBrowser/#/R-BTA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Bos taurus 29985 R-CEL-1247935 https://reactome.org/PathwayBrowser/#/R-CEL-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Caenorhabditis elegans 29985 R-CEL-174367 https://reactome.org/PathwayBrowser/#/R-CEL-174367 GCL ligates L-Glu to L-Cys IEA Caenorhabditis elegans 29985 R-CEL-197271 https://reactome.org/PathwayBrowser/#/R-CEL-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Caenorhabditis elegans 29985 R-CEL-197958 https://reactome.org/PathwayBrowser/#/R-CEL-197958 FPGS-2 transforms THF to THFPG IEA Caenorhabditis elegans 29985 R-CEL-200681 https://reactome.org/PathwayBrowser/#/R-CEL-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Caenorhabditis elegans 29985 R-CEL-200682 https://reactome.org/PathwayBrowser/#/R-CEL-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Caenorhabditis elegans 29985 R-CEL-210404 https://reactome.org/PathwayBrowser/#/R-CEL-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Caenorhabditis elegans 29985 R-CEL-210426 https://reactome.org/PathwayBrowser/#/R-CEL-210426 Glutamate synaptic vesicle docking and priming IEA Caenorhabditis elegans 29985 R-CEL-210430 https://reactome.org/PathwayBrowser/#/R-CEL-210430 Release of L-Glutamate at the synapse IEA Caenorhabditis elegans 29985 R-CEL-210439 https://reactome.org/PathwayBrowser/#/R-CEL-210439 glutamate uptake by astrocytes IEA Caenorhabditis elegans 29985 R-CEL-210444 https://reactome.org/PathwayBrowser/#/R-CEL-210444 L-Glutamate loading of synaptic vesicle IEA Caenorhabditis elegans 29985 R-CEL-266046 https://reactome.org/PathwayBrowser/#/R-CEL-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Caenorhabditis elegans 29985 R-CEL-372448 https://reactome.org/PathwayBrowser/#/R-CEL-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Caenorhabditis elegans 29985 R-CEL-373075 https://reactome.org/PathwayBrowser/#/R-CEL-373075 Metabotropic glutamate receptors bind glutamate IEA Caenorhabditis elegans 29985 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 29985 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 29985 R-CEL-3928627 https://reactome.org/PathwayBrowser/#/R-CEL-3928627 EPHB phosphorylates TIAM1 IEA Caenorhabditis elegans 29985 R-CEL-3928645 https://reactome.org/PathwayBrowser/#/R-CEL-3928645 EPHB:NMDAR binds TIAM1 IEA Caenorhabditis elegans 29985 R-CEL-399711 https://reactome.org/PathwayBrowser/#/R-CEL-399711 Activation of Ca impermeable AMPA receptors IEA Caenorhabditis elegans 29985 R-CEL-399712 https://reactome.org/PathwayBrowser/#/R-CEL-399712 Activation of Ca permeable AMPA receptors IEA Caenorhabditis elegans 29985 R-CEL-4093336 https://reactome.org/PathwayBrowser/#/R-CEL-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 29985 R-CEL-420975 https://reactome.org/PathwayBrowser/#/R-CEL-420975 Ca impermeable AMPA receptor ligand binding IEA Caenorhabditis elegans 29985 R-CEL-420977 https://reactome.org/PathwayBrowser/#/R-CEL-420977 Ca permeable AMPA receptor ligand binding IEA Caenorhabditis elegans 29985 R-CEL-420980 https://reactome.org/PathwayBrowser/#/R-CEL-420980 Activation of Ca permeable AMPA receptors IEA Caenorhabditis elegans 29985 R-CEL-428015 https://reactome.org/PathwayBrowser/#/R-CEL-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29985 R-CEL-428052 https://reactome.org/PathwayBrowser/#/R-CEL-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Caenorhabditis elegans 29985 R-CEL-432164 https://reactome.org/PathwayBrowser/#/R-CEL-432164 Ca2+ influx into the post-synaptic cell IEA Caenorhabditis elegans 29985 R-CEL-438037 https://reactome.org/PathwayBrowser/#/R-CEL-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Caenorhabditis elegans 29985 R-CEL-449715 https://reactome.org/PathwayBrowser/#/R-CEL-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Caenorhabditis elegans 29985 R-CEL-451283 https://reactome.org/PathwayBrowser/#/R-CEL-451283 kainate receptor binds glutamate IEA Caenorhabditis elegans 29985 R-CEL-451311 https://reactome.org/PathwayBrowser/#/R-CEL-451311 Activation of Ca-permeable Kainate receptors IEA Caenorhabditis elegans 29985 R-CEL-504054 https://reactome.org/PathwayBrowser/#/R-CEL-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Caenorhabditis elegans 29985 R-CEL-507749 https://reactome.org/PathwayBrowser/#/R-CEL-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Caenorhabditis elegans 29985 R-CEL-507775 https://reactome.org/PathwayBrowser/#/R-CEL-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Caenorhabditis elegans 29985 R-CEL-508040 https://reactome.org/PathwayBrowser/#/R-CEL-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Caenorhabditis elegans 29985 R-CEL-508179 https://reactome.org/PathwayBrowser/#/R-CEL-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Caenorhabditis elegans 29985 R-CEL-508189 https://reactome.org/PathwayBrowser/#/R-CEL-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Caenorhabditis elegans 29985 R-CEL-517444 https://reactome.org/PathwayBrowser/#/R-CEL-517444 TAT aminates HPP IEA Caenorhabditis elegans 29985 R-CEL-5433072 https://reactome.org/PathwayBrowser/#/R-CEL-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Caenorhabditis elegans 29985 R-CEL-5693783 https://reactome.org/PathwayBrowser/#/R-CEL-5693783 NAALADases hydrolyse NAAG IEA Caenorhabditis elegans 29985 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 29985 R-CEL-70523 https://reactome.org/PathwayBrowser/#/R-CEL-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Caenorhabditis elegans 29985 R-CEL-70524 https://reactome.org/PathwayBrowser/#/R-CEL-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Caenorhabditis elegans 29985 R-CEL-70581 https://reactome.org/PathwayBrowser/#/R-CEL-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Caenorhabditis elegans 29985 R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Caenorhabditis elegans 29985 R-CEL-70592 https://reactome.org/PathwayBrowser/#/R-CEL-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Caenorhabditis elegans 29985 R-CEL-70596 https://reactome.org/PathwayBrowser/#/R-CEL-70596 GOT2 dimer deaminates L-Asp IEA Caenorhabditis elegans 29985 R-CEL-70599 https://reactome.org/PathwayBrowser/#/R-CEL-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Caenorhabditis elegans 29985 R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Caenorhabditis elegans 29985 R-CEL-70606 https://reactome.org/PathwayBrowser/#/R-CEL-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Caenorhabditis elegans 29985 R-CEL-70609 https://reactome.org/PathwayBrowser/#/R-CEL-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Caenorhabditis elegans 29985 R-CEL-70613 https://reactome.org/PathwayBrowser/#/R-CEL-70613 GOT2 transaminates OA and L-Glu IEA Caenorhabditis elegans 29985 R-CEL-70654 https://reactome.org/PathwayBrowser/#/R-CEL-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Caenorhabditis elegans 29985 R-CEL-70666 https://reactome.org/PathwayBrowser/#/R-CEL-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Caenorhabditis elegans 29985 R-CEL-70723 https://reactome.org/PathwayBrowser/#/R-CEL-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Caenorhabditis elegans 29985 R-CEL-70724 https://reactome.org/PathwayBrowser/#/R-CEL-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Caenorhabditis elegans 29985 R-CEL-70940 https://reactome.org/PathwayBrowser/#/R-CEL-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Caenorhabditis elegans 29985 R-CEL-71155 https://reactome.org/PathwayBrowser/#/R-CEL-71155 TAT deaminates tyrosine IEA Caenorhabditis elegans 29985 R-CEL-73577 https://reactome.org/PathwayBrowser/#/R-CEL-73577 CAD hexamer transforms L-Gln to CAP IEA Caenorhabditis elegans 29985 R-CEL-73647 https://reactome.org/PathwayBrowser/#/R-CEL-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Caenorhabditis elegans 29985 R-CEL-73792 https://reactome.org/PathwayBrowser/#/R-CEL-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Caenorhabditis elegans 29985 R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 29985 R-CEL-73815 https://reactome.org/PathwayBrowser/#/R-CEL-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Caenorhabditis elegans 29985 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 29985 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 29985 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 29985 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 29985 R-CEL-8849878 https://reactome.org/PathwayBrowser/#/R-CEL-8849878 PSD-95 binds NMDA receptor IEA Caenorhabditis elegans 29985 R-CEL-8849881 https://reactome.org/PathwayBrowser/#/R-CEL-8849881 SALM2 associate with AMPA and NMDA receptors IEA Caenorhabditis elegans 29985 R-CEL-8849906 https://reactome.org/PathwayBrowser/#/R-CEL-8849906 SALM1 binds NMDA receptor IEA Caenorhabditis elegans 29985 R-CEL-8875623 https://reactome.org/PathwayBrowser/#/R-CEL-8875623 SLC25A18,22 import L-Glu, H+ IEA Caenorhabditis elegans 29985 R-CEL-888572 https://reactome.org/PathwayBrowser/#/R-CEL-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Caenorhabditis elegans 29985 R-CEL-888577 https://reactome.org/PathwayBrowser/#/R-CEL-888577 Synthesis of GABA by GAD2 IEA Caenorhabditis elegans 29985 R-CEL-8943279 https://reactome.org/PathwayBrowser/#/R-CEL-8943279 GGT dimers hydrolyse GSH IEA Caenorhabditis elegans 29985 R-CEL-916855 https://reactome.org/PathwayBrowser/#/R-CEL-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Caenorhabditis elegans 29985 R-CEL-9748957 https://reactome.org/PathwayBrowser/#/R-CEL-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Caenorhabditis elegans 29985 R-CEL-9753634 https://reactome.org/PathwayBrowser/#/R-CEL-9753634 GGT dimers hydrolyse APAP-SG IEA Caenorhabditis elegans 29985 R-CEL-977333 https://reactome.org/PathwayBrowser/#/R-CEL-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Caenorhabditis elegans 29985 R-CFA-1247935 https://reactome.org/PathwayBrowser/#/R-CFA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Canis familiaris 29985 R-CFA-174367 https://reactome.org/PathwayBrowser/#/R-CFA-174367 GCL ligates L-Glu to L-Cys IEA Canis familiaris 29985 R-CFA-197271 https://reactome.org/PathwayBrowser/#/R-CFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Canis familiaris 29985 R-CFA-197958 https://reactome.org/PathwayBrowser/#/R-CFA-197958 FPGS-2 transforms THF to THFPG IEA Canis familiaris 29985 R-CFA-200681 https://reactome.org/PathwayBrowser/#/R-CFA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Canis familiaris 29985 R-CFA-200682 https://reactome.org/PathwayBrowser/#/R-CFA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Canis familiaris 29985 R-CFA-210404 https://reactome.org/PathwayBrowser/#/R-CFA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Canis familiaris 29985 R-CFA-210426 https://reactome.org/PathwayBrowser/#/R-CFA-210426 Glutamate synaptic vesicle docking and priming IEA Canis familiaris 29985 R-CFA-210430 https://reactome.org/PathwayBrowser/#/R-CFA-210430 Release of L-Glutamate at the synapse IEA Canis familiaris 29985 R-CFA-210439 https://reactome.org/PathwayBrowser/#/R-CFA-210439 glutamate uptake by astrocytes IEA Canis familiaris 29985 R-CFA-210444 https://reactome.org/PathwayBrowser/#/R-CFA-210444 L-Glutamate loading of synaptic vesicle IEA Canis familiaris 29985 R-CFA-266046 https://reactome.org/PathwayBrowser/#/R-CFA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Canis familiaris 29985 R-CFA-372448 https://reactome.org/PathwayBrowser/#/R-CFA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Canis familiaris 29985 R-CFA-373075 https://reactome.org/PathwayBrowser/#/R-CFA-373075 Metabotropic glutamate receptors bind glutamate IEA Canis familiaris 29985 R-CFA-378513 https://reactome.org/PathwayBrowser/#/R-CFA-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Canis familiaris 29985 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 29985 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 29985 R-CFA-3928627 https://reactome.org/PathwayBrowser/#/R-CFA-3928627 EPHB phosphorylates TIAM1 IEA Canis familiaris 29985 R-CFA-3928645 https://reactome.org/PathwayBrowser/#/R-CFA-3928645 EPHB:NMDAR binds TIAM1 IEA Canis familiaris 29985 R-CFA-399711 https://reactome.org/PathwayBrowser/#/R-CFA-399711 Activation of Ca impermeable AMPA receptors IEA Canis familiaris 29985 R-CFA-399712 https://reactome.org/PathwayBrowser/#/R-CFA-399712 Activation of Ca permeable AMPA receptors IEA Canis familiaris 29985 R-CFA-4093336 https://reactome.org/PathwayBrowser/#/R-CFA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 29985 R-CFA-420975 https://reactome.org/PathwayBrowser/#/R-CFA-420975 Ca impermeable AMPA receptor ligand binding IEA Canis familiaris 29985 R-CFA-420977 https://reactome.org/PathwayBrowser/#/R-CFA-420977 Ca permeable AMPA receptor ligand binding IEA Canis familiaris 29985 R-CFA-420980 https://reactome.org/PathwayBrowser/#/R-CFA-420980 Activation of Ca permeable AMPA receptors IEA Canis familiaris 29985 R-CFA-428015 https://reactome.org/PathwayBrowser/#/R-CFA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Canis familiaris 29985 R-CFA-428052 https://reactome.org/PathwayBrowser/#/R-CFA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Canis familiaris 29985 R-CFA-432164 https://reactome.org/PathwayBrowser/#/R-CFA-432164 Ca2+ influx into the post-synaptic cell IEA Canis familiaris 29985 R-CFA-438037 https://reactome.org/PathwayBrowser/#/R-CFA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Canis familiaris 29985 R-CFA-444705 https://reactome.org/PathwayBrowser/#/R-CFA-444705 T1R1/T1R3 dimer is the umami taste receptor IEA Canis familiaris 29985 R-CFA-449715 https://reactome.org/PathwayBrowser/#/R-CFA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Canis familiaris 29985 R-CFA-451283 https://reactome.org/PathwayBrowser/#/R-CFA-451283 kainate receptor binds glutamate IEA Canis familiaris 29985 R-CFA-451309 https://reactome.org/PathwayBrowser/#/R-CFA-451309 Edited Kainate Receptor binds glutamate IEA Canis familiaris 29985 R-CFA-451310 https://reactome.org/PathwayBrowser/#/R-CFA-451310 Activation of Edited Kainate receptors IEA Canis familiaris 29985 R-CFA-451311 https://reactome.org/PathwayBrowser/#/R-CFA-451311 Activation of Ca-permeable Kainate receptors IEA Canis familiaris 29985 R-CFA-500708 https://reactome.org/PathwayBrowser/#/R-CFA-500708 GRIK3 homomer binds glutamate IEA Canis familiaris 29985 R-CFA-500717 https://reactome.org/PathwayBrowser/#/R-CFA-500717 Activation of GRIK3 homomer IEA Canis familiaris 29985 R-CFA-504054 https://reactome.org/PathwayBrowser/#/R-CFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Canis familiaris 29985 R-CFA-507749 https://reactome.org/PathwayBrowser/#/R-CFA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Canis familiaris 29985 R-CFA-507775 https://reactome.org/PathwayBrowser/#/R-CFA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Canis familiaris 29985 R-CFA-508040 https://reactome.org/PathwayBrowser/#/R-CFA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Canis familiaris 29985 R-CFA-508179 https://reactome.org/PathwayBrowser/#/R-CFA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Canis familiaris 29985 R-CFA-508189 https://reactome.org/PathwayBrowser/#/R-CFA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Canis familiaris 29985 R-CFA-508561 https://reactome.org/PathwayBrowser/#/R-CFA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Canis familiaris 29985 R-CFA-517444 https://reactome.org/PathwayBrowser/#/R-CFA-517444 TAT aminates HPP IEA Canis familiaris 29985 R-CFA-5433072 https://reactome.org/PathwayBrowser/#/R-CFA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Canis familiaris 29985 R-CFA-5672965 https://reactome.org/PathwayBrowser/#/R-CFA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Canis familiaris 29985 R-CFA-5693783 https://reactome.org/PathwayBrowser/#/R-CFA-5693783 NAALADases hydrolyse NAAG IEA Canis familiaris 29985 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 29985 R-CFA-70523 https://reactome.org/PathwayBrowser/#/R-CFA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Canis familiaris 29985 R-CFA-70524 https://reactome.org/PathwayBrowser/#/R-CFA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Canis familiaris 29985 R-CFA-70542 https://reactome.org/PathwayBrowser/#/R-CFA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Canis familiaris 29985 R-CFA-70581 https://reactome.org/PathwayBrowser/#/R-CFA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Canis familiaris 29985 R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Canis familiaris 29985 R-CFA-70592 https://reactome.org/PathwayBrowser/#/R-CFA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Canis familiaris 29985 R-CFA-70596 https://reactome.org/PathwayBrowser/#/R-CFA-70596 GOT2 dimer deaminates L-Asp IEA Canis familiaris 29985 R-CFA-70599 https://reactome.org/PathwayBrowser/#/R-CFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Canis familiaris 29985 R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Canis familiaris 29985 R-CFA-70606 https://reactome.org/PathwayBrowser/#/R-CFA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Canis familiaris 29985 R-CFA-70609 https://reactome.org/PathwayBrowser/#/R-CFA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Canis familiaris 29985 R-CFA-70613 https://reactome.org/PathwayBrowser/#/R-CFA-70613 GOT2 transaminates OA and L-Glu IEA Canis familiaris 29985 R-CFA-70654 https://reactome.org/PathwayBrowser/#/R-CFA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Canis familiaris 29985 R-CFA-70666 https://reactome.org/PathwayBrowser/#/R-CFA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Canis familiaris 29985 R-CFA-70679 https://reactome.org/PathwayBrowser/#/R-CFA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Canis familiaris 29985 R-CFA-70723 https://reactome.org/PathwayBrowser/#/R-CFA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Canis familiaris 29985 R-CFA-70724 https://reactome.org/PathwayBrowser/#/R-CFA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Canis familiaris 29985 R-CFA-70920 https://reactome.org/PathwayBrowser/#/R-CFA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Canis familiaris 29985 R-CFA-70940 https://reactome.org/PathwayBrowser/#/R-CFA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Canis familiaris 29985 R-CFA-70952 https://reactome.org/PathwayBrowser/#/R-CFA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Canis familiaris 29985 R-CFA-71155 https://reactome.org/PathwayBrowser/#/R-CFA-71155 TAT deaminates tyrosine IEA Canis familiaris 29985 R-CFA-73577 https://reactome.org/PathwayBrowser/#/R-CFA-73577 CAD hexamer transforms L-Gln to CAP IEA Canis familiaris 29985 R-CFA-73647 https://reactome.org/PathwayBrowser/#/R-CFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Canis familiaris 29985 R-CFA-73792 https://reactome.org/PathwayBrowser/#/R-CFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Canis familiaris 29985 R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 29985 R-CFA-73815 https://reactome.org/PathwayBrowser/#/R-CFA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Canis familiaris 29985 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 29985 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 29985 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 29985 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 29985 R-CFA-8849878 https://reactome.org/PathwayBrowser/#/R-CFA-8849878 PSD-95 binds NMDA receptor IEA Canis familiaris 29985 R-CFA-8849881 https://reactome.org/PathwayBrowser/#/R-CFA-8849881 SALM2 associate with AMPA and NMDA receptors IEA Canis familiaris 29985 R-CFA-8849906 https://reactome.org/PathwayBrowser/#/R-CFA-8849906 SALM1 binds NMDA receptor IEA Canis familiaris 29985 R-CFA-8865774 https://reactome.org/PathwayBrowser/#/R-CFA-8865774 TTLLs polyglutamylate tubulin IEA Canis familiaris 29985 R-CFA-8875623 https://reactome.org/PathwayBrowser/#/R-CFA-8875623 SLC25A18,22 import L-Glu, H+ IEA Canis familiaris 29985 R-CFA-888572 https://reactome.org/PathwayBrowser/#/R-CFA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Canis familiaris 29985 R-CFA-888577 https://reactome.org/PathwayBrowser/#/R-CFA-888577 Synthesis of GABA by GAD2 IEA Canis familiaris 29985 R-CFA-893583 https://reactome.org/PathwayBrowser/#/R-CFA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Canis familiaris 29985 R-CFA-8942575 https://reactome.org/PathwayBrowser/#/R-CFA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Canis familiaris 29985 R-CFA-8943279 https://reactome.org/PathwayBrowser/#/R-CFA-8943279 GGT dimers hydrolyse GSH IEA Canis familiaris 29985 R-CFA-916855 https://reactome.org/PathwayBrowser/#/R-CFA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Canis familiaris 29985 R-CFA-9717206 https://reactome.org/PathwayBrowser/#/R-CFA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Canis familiaris 29985 R-CFA-9748957 https://reactome.org/PathwayBrowser/#/R-CFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Canis familiaris 29985 R-CFA-9753634 https://reactome.org/PathwayBrowser/#/R-CFA-9753634 GGT dimers hydrolyse APAP-SG IEA Canis familiaris 29985 R-CFA-977333 https://reactome.org/PathwayBrowser/#/R-CFA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Canis familiaris 29985 R-DDI-1247935 https://reactome.org/PathwayBrowser/#/R-DDI-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Dictyostelium discoideum 29985 R-DDI-197271 https://reactome.org/PathwayBrowser/#/R-DDI-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Dictyostelium discoideum 29985 R-DDI-197958 https://reactome.org/PathwayBrowser/#/R-DDI-197958 FPGS-2 transforms THF to THFPG IEA Dictyostelium discoideum 29985 R-DDI-200681 https://reactome.org/PathwayBrowser/#/R-DDI-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Dictyostelium discoideum 29985 R-DDI-200682 https://reactome.org/PathwayBrowser/#/R-DDI-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Dictyostelium discoideum 29985 R-DDI-210444 https://reactome.org/PathwayBrowser/#/R-DDI-210444 L-Glutamate loading of synaptic vesicle IEA Dictyostelium discoideum 29985 R-DDI-372448 https://reactome.org/PathwayBrowser/#/R-DDI-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Dictyostelium discoideum 29985 R-DDI-428052 https://reactome.org/PathwayBrowser/#/R-DDI-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Dictyostelium discoideum 29985 R-DDI-449715 https://reactome.org/PathwayBrowser/#/R-DDI-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Dictyostelium discoideum 29985 R-DDI-504054 https://reactome.org/PathwayBrowser/#/R-DDI-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Dictyostelium discoideum 29985 R-DDI-507749 https://reactome.org/PathwayBrowser/#/R-DDI-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Dictyostelium discoideum 29985 R-DDI-507775 https://reactome.org/PathwayBrowser/#/R-DDI-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Dictyostelium discoideum 29985 R-DDI-508179 https://reactome.org/PathwayBrowser/#/R-DDI-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Dictyostelium discoideum 29985 R-DDI-508189 https://reactome.org/PathwayBrowser/#/R-DDI-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Dictyostelium discoideum 29985 R-DDI-508561 https://reactome.org/PathwayBrowser/#/R-DDI-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Dictyostelium discoideum 29985 R-DDI-517444 https://reactome.org/PathwayBrowser/#/R-DDI-517444 TAT aminates HPP IEA Dictyostelium discoideum 29985 R-DDI-70523 https://reactome.org/PathwayBrowser/#/R-DDI-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Dictyostelium discoideum 29985 R-DDI-70524 https://reactome.org/PathwayBrowser/#/R-DDI-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Dictyostelium discoideum 29985 R-DDI-70542 https://reactome.org/PathwayBrowser/#/R-DDI-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Dictyostelium discoideum 29985 R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Dictyostelium discoideum 29985 R-DDI-70596 https://reactome.org/PathwayBrowser/#/R-DDI-70596 GOT2 dimer deaminates L-Asp IEA Dictyostelium discoideum 29985 R-DDI-70599 https://reactome.org/PathwayBrowser/#/R-DDI-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Dictyostelium discoideum 29985 R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Dictyostelium discoideum 29985 R-DDI-70613 https://reactome.org/PathwayBrowser/#/R-DDI-70613 GOT2 transaminates OA and L-Glu IEA Dictyostelium discoideum 29985 R-DDI-70654 https://reactome.org/PathwayBrowser/#/R-DDI-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Dictyostelium discoideum 29985 R-DDI-70666 https://reactome.org/PathwayBrowser/#/R-DDI-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Dictyostelium discoideum 29985 R-DDI-70723 https://reactome.org/PathwayBrowser/#/R-DDI-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Dictyostelium discoideum 29985 R-DDI-70724 https://reactome.org/PathwayBrowser/#/R-DDI-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Dictyostelium discoideum 29985 R-DDI-70920 https://reactome.org/PathwayBrowser/#/R-DDI-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Dictyostelium discoideum 29985 R-DDI-70940 https://reactome.org/PathwayBrowser/#/R-DDI-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Dictyostelium discoideum 29985 R-DDI-70952 https://reactome.org/PathwayBrowser/#/R-DDI-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Dictyostelium discoideum 29985 R-DDI-71155 https://reactome.org/PathwayBrowser/#/R-DDI-71155 TAT deaminates tyrosine IEA Dictyostelium discoideum 29985 R-DDI-73577 https://reactome.org/PathwayBrowser/#/R-DDI-73577 CAD hexamer transforms L-Gln to CAP IEA Dictyostelium discoideum 29985 R-DDI-73647 https://reactome.org/PathwayBrowser/#/R-DDI-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Dictyostelium discoideum 29985 R-DDI-73792 https://reactome.org/PathwayBrowser/#/R-DDI-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Dictyostelium discoideum 29985 R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 29985 R-DDI-8875623 https://reactome.org/PathwayBrowser/#/R-DDI-8875623 SLC25A18,22 import L-Glu, H+ IEA Dictyostelium discoideum 29985 R-DDI-893583 https://reactome.org/PathwayBrowser/#/R-DDI-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Dictyostelium discoideum 29985 R-DDI-916855 https://reactome.org/PathwayBrowser/#/R-DDI-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Dictyostelium discoideum 29985 R-DDI-9748957 https://reactome.org/PathwayBrowser/#/R-DDI-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Dictyostelium discoideum 29985 R-DDI-977333 https://reactome.org/PathwayBrowser/#/R-DDI-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Dictyostelium discoideum 29985 R-DME-1247935 https://reactome.org/PathwayBrowser/#/R-DME-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Drosophila melanogaster 29985 R-DME-174367 https://reactome.org/PathwayBrowser/#/R-DME-174367 GCL ligates L-Glu to L-Cys IEA Drosophila melanogaster 29985 R-DME-197271 https://reactome.org/PathwayBrowser/#/R-DME-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Drosophila melanogaster 29985 R-DME-197958 https://reactome.org/PathwayBrowser/#/R-DME-197958 FPGS-2 transforms THF to THFPG IEA Drosophila melanogaster 29985 R-DME-200681 https://reactome.org/PathwayBrowser/#/R-DME-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Drosophila melanogaster 29985 R-DME-200682 https://reactome.org/PathwayBrowser/#/R-DME-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Drosophila melanogaster 29985 R-DME-210404 https://reactome.org/PathwayBrowser/#/R-DME-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Drosophila melanogaster 29985 R-DME-210426 https://reactome.org/PathwayBrowser/#/R-DME-210426 Glutamate synaptic vesicle docking and priming IEA Drosophila melanogaster 29985 R-DME-210430 https://reactome.org/PathwayBrowser/#/R-DME-210430 Release of L-Glutamate at the synapse IEA Drosophila melanogaster 29985 R-DME-210439 https://reactome.org/PathwayBrowser/#/R-DME-210439 glutamate uptake by astrocytes IEA Drosophila melanogaster 29985 R-DME-210444 https://reactome.org/PathwayBrowser/#/R-DME-210444 L-Glutamate loading of synaptic vesicle IEA Drosophila melanogaster 29985 R-DME-266046 https://reactome.org/PathwayBrowser/#/R-DME-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Drosophila melanogaster 29985 R-DME-372448 https://reactome.org/PathwayBrowser/#/R-DME-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Drosophila melanogaster 29985 R-DME-373075 https://reactome.org/PathwayBrowser/#/R-DME-373075 Metabotropic glutamate receptors bind glutamate IEA Drosophila melanogaster 29985 R-DME-378513 https://reactome.org/PathwayBrowser/#/R-DME-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Drosophila melanogaster 29985 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 29985 R-DME-3928627 https://reactome.org/PathwayBrowser/#/R-DME-3928627 EPHB phosphorylates TIAM1 IEA Drosophila melanogaster 29985 R-DME-3928645 https://reactome.org/PathwayBrowser/#/R-DME-3928645 EPHB:NMDAR binds TIAM1 IEA Drosophila melanogaster 29985 R-DME-399711 https://reactome.org/PathwayBrowser/#/R-DME-399711 Activation of Ca impermeable AMPA receptors IEA Drosophila melanogaster 29985 R-DME-399712 https://reactome.org/PathwayBrowser/#/R-DME-399712 Activation of Ca permeable AMPA receptors IEA Drosophila melanogaster 29985 R-DME-4093336 https://reactome.org/PathwayBrowser/#/R-DME-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 29985 R-DME-420975 https://reactome.org/PathwayBrowser/#/R-DME-420975 Ca impermeable AMPA receptor ligand binding IEA Drosophila melanogaster 29985 R-DME-420977 https://reactome.org/PathwayBrowser/#/R-DME-420977 Ca permeable AMPA receptor ligand binding IEA Drosophila melanogaster 29985 R-DME-420980 https://reactome.org/PathwayBrowser/#/R-DME-420980 Activation of Ca permeable AMPA receptors IEA Drosophila melanogaster 29985 R-DME-428015 https://reactome.org/PathwayBrowser/#/R-DME-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29985 R-DME-428052 https://reactome.org/PathwayBrowser/#/R-DME-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Drosophila melanogaster 29985 R-DME-432164 https://reactome.org/PathwayBrowser/#/R-DME-432164 Ca2+ influx into the post-synaptic cell IEA Drosophila melanogaster 29985 R-DME-438037 https://reactome.org/PathwayBrowser/#/R-DME-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Drosophila melanogaster 29985 R-DME-449715 https://reactome.org/PathwayBrowser/#/R-DME-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Drosophila melanogaster 29985 R-DME-451283 https://reactome.org/PathwayBrowser/#/R-DME-451283 kainate receptor binds glutamate IEA Drosophila melanogaster 29985 R-DME-451309 https://reactome.org/PathwayBrowser/#/R-DME-451309 Edited Kainate Receptor binds glutamate IEA Drosophila melanogaster 29985 R-DME-451310 https://reactome.org/PathwayBrowser/#/R-DME-451310 Activation of Edited Kainate receptors IEA Drosophila melanogaster 29985 R-DME-451311 https://reactome.org/PathwayBrowser/#/R-DME-451311 Activation of Ca-permeable Kainate receptors IEA Drosophila melanogaster 29985 R-DME-500708 https://reactome.org/PathwayBrowser/#/R-DME-500708 GRIK3 homomer binds glutamate IEA Drosophila melanogaster 29985 R-DME-500717 https://reactome.org/PathwayBrowser/#/R-DME-500717 Activation of GRIK3 homomer IEA Drosophila melanogaster 29985 R-DME-504054 https://reactome.org/PathwayBrowser/#/R-DME-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Drosophila melanogaster 29985 R-DME-507749 https://reactome.org/PathwayBrowser/#/R-DME-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Drosophila melanogaster 29985 R-DME-507775 https://reactome.org/PathwayBrowser/#/R-DME-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Drosophila melanogaster 29985 R-DME-508040 https://reactome.org/PathwayBrowser/#/R-DME-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Drosophila melanogaster 29985 R-DME-508179 https://reactome.org/PathwayBrowser/#/R-DME-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Drosophila melanogaster 29985 R-DME-508189 https://reactome.org/PathwayBrowser/#/R-DME-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Drosophila melanogaster 29985 R-DME-517444 https://reactome.org/PathwayBrowser/#/R-DME-517444 TAT aminates HPP IEA Drosophila melanogaster 29985 R-DME-5433072 https://reactome.org/PathwayBrowser/#/R-DME-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Drosophila melanogaster 29985 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 29985 R-DME-70523 https://reactome.org/PathwayBrowser/#/R-DME-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Drosophila melanogaster 29985 R-DME-70524 https://reactome.org/PathwayBrowser/#/R-DME-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Drosophila melanogaster 29985 R-DME-70581 https://reactome.org/PathwayBrowser/#/R-DME-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Drosophila melanogaster 29985 R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Drosophila melanogaster 29985 R-DME-70592 https://reactome.org/PathwayBrowser/#/R-DME-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Drosophila melanogaster 29985 R-DME-70596 https://reactome.org/PathwayBrowser/#/R-DME-70596 GOT2 dimer deaminates L-Asp IEA Drosophila melanogaster 29985 R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Drosophila melanogaster 29985 R-DME-70606 https://reactome.org/PathwayBrowser/#/R-DME-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Drosophila melanogaster 29985 R-DME-70609 https://reactome.org/PathwayBrowser/#/R-DME-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Drosophila melanogaster 29985 R-DME-70613 https://reactome.org/PathwayBrowser/#/R-DME-70613 GOT2 transaminates OA and L-Glu IEA Drosophila melanogaster 29985 R-DME-70654 https://reactome.org/PathwayBrowser/#/R-DME-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Drosophila melanogaster 29985 R-DME-70666 https://reactome.org/PathwayBrowser/#/R-DME-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Drosophila melanogaster 29985 R-DME-70723 https://reactome.org/PathwayBrowser/#/R-DME-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Drosophila melanogaster 29985 R-DME-70724 https://reactome.org/PathwayBrowser/#/R-DME-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Drosophila melanogaster 29985 R-DME-70940 https://reactome.org/PathwayBrowser/#/R-DME-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Drosophila melanogaster 29985 R-DME-71155 https://reactome.org/PathwayBrowser/#/R-DME-71155 TAT deaminates tyrosine IEA Drosophila melanogaster 29985 R-DME-73577 https://reactome.org/PathwayBrowser/#/R-DME-73577 CAD hexamer transforms L-Gln to CAP IEA Drosophila melanogaster 29985 R-DME-73647 https://reactome.org/PathwayBrowser/#/R-DME-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Drosophila melanogaster 29985 R-DME-73792 https://reactome.org/PathwayBrowser/#/R-DME-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Drosophila melanogaster 29985 R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 29985 R-DME-73815 https://reactome.org/PathwayBrowser/#/R-DME-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Drosophila melanogaster 29985 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 29985 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 29985 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 29985 R-DME-8849878 https://reactome.org/PathwayBrowser/#/R-DME-8849878 PSD-95 binds NMDA receptor IEA Drosophila melanogaster 29985 R-DME-8849881 https://reactome.org/PathwayBrowser/#/R-DME-8849881 SALM2 associate with AMPA and NMDA receptors IEA Drosophila melanogaster 29985 R-DME-8849906 https://reactome.org/PathwayBrowser/#/R-DME-8849906 SALM1 binds NMDA receptor IEA Drosophila melanogaster 29985 R-DME-8875623 https://reactome.org/PathwayBrowser/#/R-DME-8875623 SLC25A18,22 import L-Glu, H+ IEA Drosophila melanogaster 29985 R-DME-888572 https://reactome.org/PathwayBrowser/#/R-DME-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Drosophila melanogaster 29985 R-DME-888577 https://reactome.org/PathwayBrowser/#/R-DME-888577 Synthesis of GABA by GAD2 IEA Drosophila melanogaster 29985 R-DME-8943279 https://reactome.org/PathwayBrowser/#/R-DME-8943279 GGT dimers hydrolyse GSH IEA Drosophila melanogaster 29985 R-DME-916855 https://reactome.org/PathwayBrowser/#/R-DME-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Drosophila melanogaster 29985 R-DME-9748957 https://reactome.org/PathwayBrowser/#/R-DME-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Drosophila melanogaster 29985 R-DME-9753634 https://reactome.org/PathwayBrowser/#/R-DME-9753634 GGT dimers hydrolyse APAP-SG IEA Drosophila melanogaster 29985 R-DME-977333 https://reactome.org/PathwayBrowser/#/R-DME-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Drosophila melanogaster 29985 R-DRE-1247935 https://reactome.org/PathwayBrowser/#/R-DRE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Danio rerio 29985 R-DRE-197271 https://reactome.org/PathwayBrowser/#/R-DRE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Danio rerio 29985 R-DRE-197958 https://reactome.org/PathwayBrowser/#/R-DRE-197958 FPGS-2 transforms THF to THFPG IEA Danio rerio 29985 R-DRE-200681 https://reactome.org/PathwayBrowser/#/R-DRE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Danio rerio 29985 R-DRE-200682 https://reactome.org/PathwayBrowser/#/R-DRE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Danio rerio 29985 R-DRE-210404 https://reactome.org/PathwayBrowser/#/R-DRE-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Danio rerio 29985 R-DRE-210439 https://reactome.org/PathwayBrowser/#/R-DRE-210439 glutamate uptake by astrocytes IEA Danio rerio 29985 R-DRE-210444 https://reactome.org/PathwayBrowser/#/R-DRE-210444 L-Glutamate loading of synaptic vesicle IEA Danio rerio 29985 R-DRE-372448 https://reactome.org/PathwayBrowser/#/R-DRE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Danio rerio 29985 R-DRE-373075 https://reactome.org/PathwayBrowser/#/R-DRE-373075 Metabotropic glutamate receptors bind glutamate IEA Danio rerio 29985 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 29985 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 29985 R-DRE-399712 https://reactome.org/PathwayBrowser/#/R-DRE-399712 Activation of Ca permeable AMPA receptors IEA Danio rerio 29985 R-DRE-420977 https://reactome.org/PathwayBrowser/#/R-DRE-420977 Ca permeable AMPA receptor ligand binding IEA Danio rerio 29985 R-DRE-420980 https://reactome.org/PathwayBrowser/#/R-DRE-420980 Activation of Ca permeable AMPA receptors IEA Danio rerio 29985 R-DRE-428015 https://reactome.org/PathwayBrowser/#/R-DRE-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Danio rerio 29985 R-DRE-428052 https://reactome.org/PathwayBrowser/#/R-DRE-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Danio rerio 29985 R-DRE-432164 https://reactome.org/PathwayBrowser/#/R-DRE-432164 Ca2+ influx into the post-synaptic cell IEA Danio rerio 29985 R-DRE-444705 https://reactome.org/PathwayBrowser/#/R-DRE-444705 T1R1/T1R3 dimer is the umami taste receptor IEA Danio rerio 29985 R-DRE-449715 https://reactome.org/PathwayBrowser/#/R-DRE-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Danio rerio 29985 R-DRE-504054 https://reactome.org/PathwayBrowser/#/R-DRE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Danio rerio 29985 R-DRE-508179 https://reactome.org/PathwayBrowser/#/R-DRE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Danio rerio 29985 R-DRE-508189 https://reactome.org/PathwayBrowser/#/R-DRE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Danio rerio 29985 R-DRE-517444 https://reactome.org/PathwayBrowser/#/R-DRE-517444 TAT aminates HPP IEA Danio rerio 29985 R-DRE-5693783 https://reactome.org/PathwayBrowser/#/R-DRE-5693783 NAALADases hydrolyse NAAG IEA Danio rerio 29985 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 29985 R-DRE-70523 https://reactome.org/PathwayBrowser/#/R-DRE-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Danio rerio 29985 R-DRE-70524 https://reactome.org/PathwayBrowser/#/R-DRE-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Danio rerio 29985 R-DRE-70542 https://reactome.org/PathwayBrowser/#/R-DRE-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Danio rerio 29985 R-DRE-70581 https://reactome.org/PathwayBrowser/#/R-DRE-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Danio rerio 29985 R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Danio rerio 29985 R-DRE-70592 https://reactome.org/PathwayBrowser/#/R-DRE-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Danio rerio 29985 R-DRE-70596 https://reactome.org/PathwayBrowser/#/R-DRE-70596 GOT2 dimer deaminates L-Asp IEA Danio rerio 29985 R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Danio rerio 29985 R-DRE-70606 https://reactome.org/PathwayBrowser/#/R-DRE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Danio rerio 29985 R-DRE-70609 https://reactome.org/PathwayBrowser/#/R-DRE-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Danio rerio 29985 R-DRE-70613 https://reactome.org/PathwayBrowser/#/R-DRE-70613 GOT2 transaminates OA and L-Glu IEA Danio rerio 29985 R-DRE-70679 https://reactome.org/PathwayBrowser/#/R-DRE-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Danio rerio 29985 R-DRE-70723 https://reactome.org/PathwayBrowser/#/R-DRE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Danio rerio 29985 R-DRE-70724 https://reactome.org/PathwayBrowser/#/R-DRE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Danio rerio 29985 R-DRE-70940 https://reactome.org/PathwayBrowser/#/R-DRE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Danio rerio 29985 R-DRE-71155 https://reactome.org/PathwayBrowser/#/R-DRE-71155 TAT deaminates tyrosine IEA Danio rerio 29985 R-DRE-73647 https://reactome.org/PathwayBrowser/#/R-DRE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Danio rerio 29985 R-DRE-73815 https://reactome.org/PathwayBrowser/#/R-DRE-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Danio rerio 29985 R-DRE-8875623 https://reactome.org/PathwayBrowser/#/R-DRE-8875623 SLC25A18,22 import L-Glu, H+ IEA Danio rerio 29985 R-DRE-888572 https://reactome.org/PathwayBrowser/#/R-DRE-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Danio rerio 29985 R-DRE-8942575 https://reactome.org/PathwayBrowser/#/R-DRE-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Danio rerio 29985 R-DRE-916855 https://reactome.org/PathwayBrowser/#/R-DRE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Danio rerio 29985 R-DRE-9717206 https://reactome.org/PathwayBrowser/#/R-DRE-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Danio rerio 29985 R-DRE-977333 https://reactome.org/PathwayBrowser/#/R-DRE-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Danio rerio 29985 R-GGA-197271 https://reactome.org/PathwayBrowser/#/R-GGA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Gallus gallus 29985 R-GGA-197958 https://reactome.org/PathwayBrowser/#/R-GGA-197958 FPGS-2 transforms THF to THFPG IEA Gallus gallus 29985 R-GGA-200681 https://reactome.org/PathwayBrowser/#/R-GGA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Gallus gallus 29985 R-GGA-200682 https://reactome.org/PathwayBrowser/#/R-GGA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Gallus gallus 29985 R-GGA-210404 https://reactome.org/PathwayBrowser/#/R-GGA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Gallus gallus 29985 R-GGA-210439 https://reactome.org/PathwayBrowser/#/R-GGA-210439 glutamate uptake by astrocytes IEA Gallus gallus 29985 R-GGA-266046 https://reactome.org/PathwayBrowser/#/R-GGA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Gallus gallus 29985 R-GGA-372448 https://reactome.org/PathwayBrowser/#/R-GGA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Gallus gallus 29985 R-GGA-372559 https://reactome.org/PathwayBrowser/#/R-GGA-372559 aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate TAS Gallus gallus 29985 R-GGA-372564 https://reactome.org/PathwayBrowser/#/R-GGA-372564 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) TAS Gallus gallus 29985 R-GGA-372717 https://reactome.org/PathwayBrowser/#/R-GGA-372717 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) TAS Gallus gallus 29985 R-GGA-372719 https://reactome.org/PathwayBrowser/#/R-GGA-372719 aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate TAS Gallus gallus 29985 R-GGA-372726 https://reactome.org/PathwayBrowser/#/R-GGA-372726 aspartate [mitochondrial matrix] + glutamate [cytosol] <=> aspartate [cytosol] + glutamate [mitochondrial matrix] IEA Gallus gallus 29985 R-GGA-373075 https://reactome.org/PathwayBrowser/#/R-GGA-373075 Metabotropic glutamate receptors bind glutamate IEA Gallus gallus 29985 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 29985 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 29985 R-GGA-3928627 https://reactome.org/PathwayBrowser/#/R-GGA-3928627 EPHB phosphorylates TIAM1 IEA Gallus gallus 29985 R-GGA-3928645 https://reactome.org/PathwayBrowser/#/R-GGA-3928645 EPHB:NMDAR binds TIAM1 IEA Gallus gallus 29985 R-GGA-399711 https://reactome.org/PathwayBrowser/#/R-GGA-399711 Activation of Ca impermeable AMPA receptors IEA Gallus gallus 29985 R-GGA-399712 https://reactome.org/PathwayBrowser/#/R-GGA-399712 Activation of Ca permeable AMPA receptors IEA Gallus gallus 29985 R-GGA-4093336 https://reactome.org/PathwayBrowser/#/R-GGA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 29985 R-GGA-419144 https://reactome.org/PathwayBrowser/#/R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate TAS Gallus gallus 29985 R-GGA-419152 https://reactome.org/PathwayBrowser/#/R-GGA-419152 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate TAS Gallus gallus 29985 R-GGA-419440 https://reactome.org/PathwayBrowser/#/R-GGA-419440 L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate IEA Gallus gallus 29985 R-GGA-420975 https://reactome.org/PathwayBrowser/#/R-GGA-420975 Ca impermeable AMPA receptor ligand binding IEA Gallus gallus 29985 R-GGA-420977 https://reactome.org/PathwayBrowser/#/R-GGA-420977 Ca permeable AMPA receptor ligand binding IEA Gallus gallus 29985 R-GGA-420980 https://reactome.org/PathwayBrowser/#/R-GGA-420980 Activation of Ca permeable AMPA receptors IEA Gallus gallus 29985 R-GGA-421218 https://reactome.org/PathwayBrowser/#/R-GGA-421218 xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate IEA Gallus gallus 29985 R-GGA-428015 https://reactome.org/PathwayBrowser/#/R-GGA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Gallus gallus 29985 R-GGA-428052 https://reactome.org/PathwayBrowser/#/R-GGA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Gallus gallus 29985 R-GGA-432164 https://reactome.org/PathwayBrowser/#/R-GGA-432164 Ca2+ influx into the post-synaptic cell IEA Gallus gallus 29985 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus 29985 R-GGA-449715 https://reactome.org/PathwayBrowser/#/R-GGA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Gallus gallus 29985 R-GGA-451283 https://reactome.org/PathwayBrowser/#/R-GGA-451283 kainate receptor binds glutamate IEA Gallus gallus 29985 R-GGA-451309 https://reactome.org/PathwayBrowser/#/R-GGA-451309 Edited Kainate Receptor binds glutamate IEA Gallus gallus 29985 R-GGA-451310 https://reactome.org/PathwayBrowser/#/R-GGA-451310 Activation of Edited Kainate receptors IEA Gallus gallus 29985 R-GGA-451311 https://reactome.org/PathwayBrowser/#/R-GGA-451311 Activation of Ca-permeable Kainate receptors IEA Gallus gallus 29985 R-GGA-500708 https://reactome.org/PathwayBrowser/#/R-GGA-500708 GRIK3 homomer binds glutamate IEA Gallus gallus 29985 R-GGA-500717 https://reactome.org/PathwayBrowser/#/R-GGA-500717 Activation of GRIK3 homomer IEA Gallus gallus 29985 R-GGA-504054 https://reactome.org/PathwayBrowser/#/R-GGA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Gallus gallus 29985 R-GGA-507749 https://reactome.org/PathwayBrowser/#/R-GGA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Gallus gallus 29985 R-GGA-507775 https://reactome.org/PathwayBrowser/#/R-GGA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Gallus gallus 29985 R-GGA-508040 https://reactome.org/PathwayBrowser/#/R-GGA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Gallus gallus 29985 R-GGA-508189 https://reactome.org/PathwayBrowser/#/R-GGA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Gallus gallus 29985 R-GGA-508561 https://reactome.org/PathwayBrowser/#/R-GGA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Gallus gallus 29985 R-GGA-517444 https://reactome.org/PathwayBrowser/#/R-GGA-517444 TAT aminates HPP IEA Gallus gallus 29985 R-GGA-5433072 https://reactome.org/PathwayBrowser/#/R-GGA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Gallus gallus 29985 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus 29985 R-GGA-5693783 https://reactome.org/PathwayBrowser/#/R-GGA-5693783 NAALADases hydrolyse NAAG IEA Gallus gallus 29985 R-GGA-70581 https://reactome.org/PathwayBrowser/#/R-GGA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Gallus gallus 29985 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Gallus gallus 29985 R-GGA-70592 https://reactome.org/PathwayBrowser/#/R-GGA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Gallus gallus 29985 R-GGA-70596 https://reactome.org/PathwayBrowser/#/R-GGA-70596 GOT2 dimer deaminates L-Asp IEA Gallus gallus 29985 R-GGA-70599 https://reactome.org/PathwayBrowser/#/R-GGA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Gallus gallus 29985 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Gallus gallus 29985 R-GGA-70606 https://reactome.org/PathwayBrowser/#/R-GGA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Gallus gallus 29985 R-GGA-70609 https://reactome.org/PathwayBrowser/#/R-GGA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Gallus gallus 29985 R-GGA-70613 https://reactome.org/PathwayBrowser/#/R-GGA-70613 GOT2 transaminates OA and L-Glu IEA Gallus gallus 29985 R-GGA-70654 https://reactome.org/PathwayBrowser/#/R-GGA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Gallus gallus 29985 R-GGA-70666 https://reactome.org/PathwayBrowser/#/R-GGA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Gallus gallus 29985 R-GGA-70679 https://reactome.org/PathwayBrowser/#/R-GGA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Gallus gallus 29985 R-GGA-70723 https://reactome.org/PathwayBrowser/#/R-GGA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Gallus gallus 29985 R-GGA-70920 https://reactome.org/PathwayBrowser/#/R-GGA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Gallus gallus 29985 R-GGA-70940 https://reactome.org/PathwayBrowser/#/R-GGA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Gallus gallus 29985 R-GGA-70952 https://reactome.org/PathwayBrowser/#/R-GGA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Gallus gallus 29985 R-GGA-71155 https://reactome.org/PathwayBrowser/#/R-GGA-71155 TAT deaminates tyrosine IEA Gallus gallus 29985 R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus 29985 R-GGA-73792 https://reactome.org/PathwayBrowser/#/R-GGA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Gallus gallus 29985 R-GGA-73815 https://reactome.org/PathwayBrowser/#/R-GGA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Gallus gallus 29985 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 29985 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 29985 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 29985 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 29985 R-GGA-8849881 https://reactome.org/PathwayBrowser/#/R-GGA-8849881 SALM2 associate with AMPA and NMDA receptors IEA Gallus gallus 29985 R-GGA-8875623 https://reactome.org/PathwayBrowser/#/R-GGA-8875623 SLC25A18,22 import L-Glu, H+ IEA Gallus gallus 29985 R-GGA-888572 https://reactome.org/PathwayBrowser/#/R-GGA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Gallus gallus 29985 R-GGA-888577 https://reactome.org/PathwayBrowser/#/R-GGA-888577 Synthesis of GABA by GAD2 IEA Gallus gallus 29985 R-GGA-893583 https://reactome.org/PathwayBrowser/#/R-GGA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Gallus gallus 29985 R-GGA-8942575 https://reactome.org/PathwayBrowser/#/R-GGA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Gallus gallus 29985 R-GGA-8943279 https://reactome.org/PathwayBrowser/#/R-GGA-8943279 GGT dimers hydrolyse GSH IEA Gallus gallus 29985 R-GGA-916855 https://reactome.org/PathwayBrowser/#/R-GGA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Gallus gallus 29985 R-GGA-9748957 https://reactome.org/PathwayBrowser/#/R-GGA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Gallus gallus 29985 R-GGA-9753634 https://reactome.org/PathwayBrowser/#/R-GGA-9753634 GGT dimers hydrolyse APAP-SG IEA Gallus gallus 29985 R-GGA-977333 https://reactome.org/PathwayBrowser/#/R-GGA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Gallus gallus 29985 R-HSA-1247935 https://reactome.org/PathwayBrowser/#/R-HSA-1247935 OPLAH hydrolyses OPRO to L-Glu TAS Homo sapiens 29985 R-HSA-174367 https://reactome.org/PathwayBrowser/#/R-HSA-174367 GCL ligates L-Glu to L-Cys TAS Homo sapiens 29985 R-HSA-197271 https://reactome.org/PathwayBrowser/#/R-HSA-197271 NADSYN1 hexamer amidates NAAD to NAD+ TAS Homo sapiens 29985 R-HSA-197958 https://reactome.org/PathwayBrowser/#/R-HSA-197958 FPGS-2 transforms THF to THFPG TAS Homo sapiens 29985 R-HSA-200681 https://reactome.org/PathwayBrowser/#/R-HSA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG TAS Homo sapiens 29985 R-HSA-200682 https://reactome.org/PathwayBrowser/#/R-HSA-200682 Mitochondrial FPGS-1 transforms THF to THFPG TAS Homo sapiens 29985 R-HSA-210404 https://reactome.org/PathwayBrowser/#/R-HSA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ TAS Homo sapiens 29985 R-HSA-210426 https://reactome.org/PathwayBrowser/#/R-HSA-210426 Glutamate synaptic vesicle docking and priming TAS Homo sapiens 29985 R-HSA-210430 https://reactome.org/PathwayBrowser/#/R-HSA-210430 Release of L-Glutamate at the synapse TAS Homo sapiens 29985 R-HSA-210439 https://reactome.org/PathwayBrowser/#/R-HSA-210439 glutamate uptake by astrocytes TAS Homo sapiens 29985 R-HSA-210444 https://reactome.org/PathwayBrowser/#/R-HSA-210444 L-Glutamate loading of synaptic vesicle TAS Homo sapiens 29985 R-HSA-212658 https://reactome.org/PathwayBrowser/#/R-HSA-212658 Tranport of L-Glutamate (mitochondrial matrix) to cytosol TAS Homo sapiens 29985 R-HSA-2161945 https://reactome.org/PathwayBrowser/#/R-HSA-2161945 EXC4 is converted to EXD4 by GGT TAS Homo sapiens 29985 R-HSA-266046 https://reactome.org/PathwayBrowser/#/R-HSA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 TAS Homo sapiens 29985 R-HSA-372448 https://reactome.org/PathwayBrowser/#/R-HSA-372448 SLC25A12,13 exchange L-Glu and L-Asp TAS Homo sapiens 29985 R-HSA-373075 https://reactome.org/PathwayBrowser/#/R-HSA-373075 Metabotropic glutamate receptors bind glutamate TAS Homo sapiens 29985 R-HSA-378513 https://reactome.org/PathwayBrowser/#/R-HSA-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate TAS Homo sapiens 29985 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 29985 R-HSA-379861 https://reactome.org/PathwayBrowser/#/R-HSA-379861 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 29985 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 29985 R-HSA-380216 https://reactome.org/PathwayBrowser/#/R-HSA-380216 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate IEA Homo sapiens 29985 R-HSA-3928583 https://reactome.org/PathwayBrowser/#/R-HSA-3928583 FYN phosphorylates NMDAR2B IEA Homo sapiens 29985 R-HSA-3928623 https://reactome.org/PathwayBrowser/#/R-HSA-3928623 EPHBs bind NMDARs IEA Homo sapiens 29985 R-HSA-3928627 https://reactome.org/PathwayBrowser/#/R-HSA-3928627 EPHB phosphorylates TIAM1 TAS Homo sapiens 29985 R-HSA-3928645 https://reactome.org/PathwayBrowser/#/R-HSA-3928645 EPHB:NMDAR binds TIAM1 TAS Homo sapiens 29985 R-HSA-399711 https://reactome.org/PathwayBrowser/#/R-HSA-399711 Activation of Ca impermeable AMPA receptors TAS Homo sapiens 29985 R-HSA-399712 https://reactome.org/PathwayBrowser/#/R-HSA-399712 Activation of Ca permeable AMPA receptors TAS Homo sapiens 29985 R-HSA-4093336 https://reactome.org/PathwayBrowser/#/R-HSA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 29985 R-HSA-420975 https://reactome.org/PathwayBrowser/#/R-HSA-420975 Ca impermeable AMPA receptor ligand binding TAS Homo sapiens 29985 R-HSA-420977 https://reactome.org/PathwayBrowser/#/R-HSA-420977 Ca permeable AMPA receptor ligand binding TAS Homo sapiens 29985 R-HSA-420980 https://reactome.org/PathwayBrowser/#/R-HSA-420980 Activation of Ca permeable AMPA receptors TAS Homo sapiens 29985 R-HSA-428015 https://reactome.org/PathwayBrowser/#/R-HSA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29985 R-HSA-428052 https://reactome.org/PathwayBrowser/#/R-HSA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ TAS Homo sapiens 29985 R-HSA-432162 https://reactome.org/PathwayBrowser/#/R-HSA-432162 Unblocking of GRIN1:GRIN2 NMDA receptors IEA Homo sapiens 29985 R-HSA-432164 https://reactome.org/PathwayBrowser/#/R-HSA-432164 Ca2+ influx into the post-synaptic cell TAS Homo sapiens 29985 R-HSA-432172 https://reactome.org/PathwayBrowser/#/R-HSA-432172 Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor IEA Homo sapiens 29985 R-HSA-438037 https://reactome.org/PathwayBrowser/#/R-HSA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors TAS Homo sapiens 29985 R-HSA-442732 https://reactome.org/PathwayBrowser/#/R-HSA-442732 NMDA-activated RASGRF1 activates RAS IEA Homo sapiens 29985 R-HSA-442760 https://reactome.org/PathwayBrowser/#/R-HSA-442760 Activation of RasGRF IEA Homo sapiens 29985 R-HSA-444705 https://reactome.org/PathwayBrowser/#/R-HSA-444705 T1R1/T1R3 dimer is the umami taste receptor TAS Homo sapiens 29985 R-HSA-445367 https://reactome.org/PathwayBrowser/#/R-HSA-445367 CaMKII binds activated NMDA receptor IEA Homo sapiens 29985 R-HSA-449715 https://reactome.org/PathwayBrowser/#/R-HSA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P TAS Homo sapiens 29985 R-HSA-451283 https://reactome.org/PathwayBrowser/#/R-HSA-451283 kainate receptor binds glutamate TAS Homo sapiens 29985 R-HSA-451309 https://reactome.org/PathwayBrowser/#/R-HSA-451309 Edited Kainate Receptor binds glutamate TAS Homo sapiens 29985 R-HSA-451310 https://reactome.org/PathwayBrowser/#/R-HSA-451310 Activation of Edited Kainate receptors TAS Homo sapiens 29985 R-HSA-451311 https://reactome.org/PathwayBrowser/#/R-HSA-451311 Activation of Ca-permeable Kainate receptors TAS Homo sapiens 29985 R-HSA-500708 https://reactome.org/PathwayBrowser/#/R-HSA-500708 GRIK3 homomer binds glutamate TAS Homo sapiens 29985 R-HSA-500717 https://reactome.org/PathwayBrowser/#/R-HSA-500717 Activation of GRIK3 homomer TAS Homo sapiens 29985 R-HSA-504054 https://reactome.org/PathwayBrowser/#/R-HSA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] TAS Homo sapiens 29985 R-HSA-507749 https://reactome.org/PathwayBrowser/#/R-HSA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala TAS Homo sapiens 29985 R-HSA-507775 https://reactome.org/PathwayBrowser/#/R-HSA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR TAS Homo sapiens 29985 R-HSA-508040 https://reactome.org/PathwayBrowser/#/R-HSA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] TAS Homo sapiens 29985 R-HSA-508179 https://reactome.org/PathwayBrowser/#/R-HSA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] TAS Homo sapiens 29985 R-HSA-508189 https://reactome.org/PathwayBrowser/#/R-HSA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] TAS Homo sapiens 29985 R-HSA-508561 https://reactome.org/PathwayBrowser/#/R-HSA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate TAS Homo sapiens 29985 R-HSA-517444 https://reactome.org/PathwayBrowser/#/R-HSA-517444 TAT aminates HPP TAS Homo sapiens 29985 R-HSA-5433072 https://reactome.org/PathwayBrowser/#/R-HSA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG TAS Homo sapiens 29985 R-HSA-5602892 https://reactome.org/PathwayBrowser/#/R-HSA-5602892 Defective GCLC does not ligate L-Glu to L-Cys TAS Homo sapiens 29985 R-HSA-5624256 https://reactome.org/PathwayBrowser/#/R-HSA-5624256 Defective SLC17A8 does not exchange cytosolic L-Glu for synaptic vesicle H+ TAS Homo sapiens 29985 R-HSA-5625015 https://reactome.org/PathwayBrowser/#/R-HSA-5625015 Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29985 R-HSA-5625029 https://reactome.org/PathwayBrowser/#/R-HSA-5625029 SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29985 R-HSA-5672965 https://reactome.org/PathwayBrowser/#/R-HSA-5672965 RAS GEFs promote RAS nucleotide exchange TAS Homo sapiens 29985 R-HSA-5693783 https://reactome.org/PathwayBrowser/#/R-HSA-5693783 NAALADases hydrolyse NAAG TAS Homo sapiens 29985 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 29985 R-HSA-70523 https://reactome.org/PathwayBrowser/#/R-HSA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR TAS Homo sapiens 29985 R-HSA-70524 https://reactome.org/PathwayBrowser/#/R-HSA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala TAS Homo sapiens 29985 R-HSA-70542 https://reactome.org/PathwayBrowser/#/R-HSA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA TAS Homo sapiens 29985 R-HSA-70581 https://reactome.org/PathwayBrowser/#/R-HSA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] TAS Homo sapiens 29985 R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] TAS Homo sapiens 29985 R-HSA-70592 https://reactome.org/PathwayBrowser/#/R-HSA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp TAS Homo sapiens 29985 R-HSA-70596 https://reactome.org/PathwayBrowser/#/R-HSA-70596 GOT2 dimer deaminates L-Asp TAS Homo sapiens 29985 R-HSA-70599 https://reactome.org/PathwayBrowser/#/R-HSA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] TAS Homo sapiens 29985 R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] TAS Homo sapiens 29985 R-HSA-70606 https://reactome.org/PathwayBrowser/#/R-HSA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] TAS Homo sapiens 29985 R-HSA-70609 https://reactome.org/PathwayBrowser/#/R-HSA-70609 glutamine + H2O => glutamate + NH4+ [GLS] TAS Homo sapiens 29985 R-HSA-70613 https://reactome.org/PathwayBrowser/#/R-HSA-70613 GOT2 transaminates OA and L-Glu TAS Homo sapiens 29985 R-HSA-70654 https://reactome.org/PathwayBrowser/#/R-HSA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] TAS Homo sapiens 29985 R-HSA-70666 https://reactome.org/PathwayBrowser/#/R-HSA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] TAS Homo sapiens 29985 R-HSA-70679 https://reactome.org/PathwayBrowser/#/R-HSA-70679 ALDH4A1 oxidises L-GluSS to Glu TAS Homo sapiens 29985 R-HSA-70723 https://reactome.org/PathwayBrowser/#/R-HSA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] TAS Homo sapiens 29985 R-HSA-70724 https://reactome.org/PathwayBrowser/#/R-HSA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] TAS Homo sapiens 29985 R-HSA-70920 https://reactome.org/PathwayBrowser/#/R-HSA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate TAS Homo sapiens 29985 R-HSA-70940 https://reactome.org/PathwayBrowser/#/R-HSA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ TAS Homo sapiens 29985 R-HSA-70952 https://reactome.org/PathwayBrowser/#/R-HSA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate TAS Homo sapiens 29985 R-HSA-71155 https://reactome.org/PathwayBrowser/#/R-HSA-71155 TAT deaminates tyrosine TAS Homo sapiens 29985 R-HSA-73577 https://reactome.org/PathwayBrowser/#/R-HSA-73577 CAD hexamer transforms L-Gln to CAP TAS Homo sapiens 29985 R-HSA-73647 https://reactome.org/PathwayBrowser/#/R-HSA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] TAS Homo sapiens 29985 R-HSA-73792 https://reactome.org/PathwayBrowser/#/R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate TAS Homo sapiens 29985 R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 29985 R-HSA-73815 https://reactome.org/PathwayBrowser/#/R-HSA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate TAS Homo sapiens 29985 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 29985 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 29985 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 29985 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 29985 R-HSA-8849878 https://reactome.org/PathwayBrowser/#/R-HSA-8849878 PSD-95 binds NMDA receptor TAS Homo sapiens 29985 R-HSA-8849881 https://reactome.org/PathwayBrowser/#/R-HSA-8849881 SALM2 associate with AMPA and NMDA receptors TAS Homo sapiens 29985 R-HSA-8849906 https://reactome.org/PathwayBrowser/#/R-HSA-8849906 SALM1 binds NMDA receptor TAS Homo sapiens 29985 R-HSA-8865774 https://reactome.org/PathwayBrowser/#/R-HSA-8865774 TTLLs polyglutamylate tubulin TAS Homo sapiens 29985 R-HSA-8866105 https://reactome.org/PathwayBrowser/#/R-HSA-8866105 CCPs deglutamylate tubulin IEA Homo sapiens 29985 R-HSA-8875623 https://reactome.org/PathwayBrowser/#/R-HSA-8875623 SLC25A18,22 import L-Glu, H+ TAS Homo sapiens 29985 R-HSA-888572 https://reactome.org/PathwayBrowser/#/R-HSA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA TAS Homo sapiens 29985 R-HSA-888577 https://reactome.org/PathwayBrowser/#/R-HSA-888577 Synthesis of GABA by GAD2 TAS Homo sapiens 29985 R-HSA-893583 https://reactome.org/PathwayBrowser/#/R-HSA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate TAS Homo sapiens 29985 R-HSA-8942575 https://reactome.org/PathwayBrowser/#/R-HSA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG TAS Homo sapiens 29985 R-HSA-8943279 https://reactome.org/PathwayBrowser/#/R-HSA-8943279 GGT dimers hydrolyse GSH TAS Homo sapiens 29985 R-HSA-8955869 https://reactome.org/PathwayBrowser/#/R-HSA-8955869 Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin IEA Homo sapiens 29985 R-HSA-9012597 https://reactome.org/PathwayBrowser/#/R-HSA-9012597 GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu IEA Homo sapiens 29985 R-HSA-9026757 https://reactome.org/PathwayBrowser/#/R-HSA-9026757 GGT hydrolyses MCTR1 to MCTR2 TAS Homo sapiens 29985 R-HSA-9026912 https://reactome.org/PathwayBrowser/#/R-HSA-9026912 GGT hydrolyses PCTR1 to PCTR2 TAS Homo sapiens 29985 R-HSA-9026927 https://reactome.org/PathwayBrowser/#/R-HSA-9026927 GGT hydrolyses RCTR1 to RCTR2 TAS Homo sapiens 29985 R-HSA-916855 https://reactome.org/PathwayBrowser/#/R-HSA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA TAS Homo sapiens 29985 R-HSA-9612085 https://reactome.org/PathwayBrowser/#/R-HSA-9612085 SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs IEA Homo sapiens 29985 R-HSA-9617326 https://reactome.org/PathwayBrowser/#/R-HSA-9617326 CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 IEA Homo sapiens 29985 R-HSA-9618750 https://reactome.org/PathwayBrowser/#/R-HSA-9618750 CaMKII phosphorylates AMPA receptor IEA Homo sapiens 29985 R-HSA-9662096 https://reactome.org/PathwayBrowser/#/R-HSA-9662096 Exocytosis of glutamate from cochlear inner hair cell IEA Homo sapiens 29985 R-HSA-9717182 https://reactome.org/PathwayBrowser/#/R-HSA-9717182 L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP and GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 29985 R-HSA-9717202 https://reactome.org/PathwayBrowser/#/R-HSA-9717202 GNAT3 exchanges GDP for GTP in L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 29985 R-HSA-9717206 https://reactome.org/PathwayBrowser/#/R-HSA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) TAS Homo sapiens 29985 R-HSA-9737035 https://reactome.org/PathwayBrowser/#/R-HSA-9737035 L-Glutamate binds GRM1 (mGluR1) IEA Homo sapiens 29985 R-HSA-9737046 https://reactome.org/PathwayBrowser/#/R-HSA-9737046 L-Glutamate binds GRM4 (mGluR4) IEA Homo sapiens 29985 R-HSA-9748957 https://reactome.org/PathwayBrowser/#/R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP TAS Homo sapiens 29985 R-HSA-9753634 https://reactome.org/PathwayBrowser/#/R-HSA-9753634 GGT dimers hydrolyse APAP-SG TAS Homo sapiens 29985 R-HSA-977333 https://reactome.org/PathwayBrowser/#/R-HSA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA TAS Homo sapiens 29985 R-MMU-1247935 https://reactome.org/PathwayBrowser/#/R-MMU-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Mus musculus 29985 R-MMU-174367 https://reactome.org/PathwayBrowser/#/R-MMU-174367 GCL ligates L-Glu to L-Cys IEA Mus musculus 29985 R-MMU-197271 https://reactome.org/PathwayBrowser/#/R-MMU-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Mus musculus 29985 R-MMU-197958 https://reactome.org/PathwayBrowser/#/R-MMU-197958 FPGS-2 transforms THF to THFPG IEA Mus musculus 29985 R-MMU-200681 https://reactome.org/PathwayBrowser/#/R-MMU-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Mus musculus 29985 R-MMU-200682 https://reactome.org/PathwayBrowser/#/R-MMU-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Mus musculus 29985 R-MMU-210404 https://reactome.org/PathwayBrowser/#/R-MMU-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Mus musculus 29985 R-MMU-210426 https://reactome.org/PathwayBrowser/#/R-MMU-210426 Glutamate synaptic vesicle docking and priming IEA Mus musculus 29985 R-MMU-210430 https://reactome.org/PathwayBrowser/#/R-MMU-210430 Release of L-Glutamate at the synapse IEA Mus musculus 29985 R-MMU-210439 https://reactome.org/PathwayBrowser/#/R-MMU-210439 glutamate uptake by astrocytes IEA Mus musculus 29985 R-MMU-210444 https://reactome.org/PathwayBrowser/#/R-MMU-210444 L-Glutamate loading of synaptic vesicle IEA Mus musculus 29985 R-MMU-266046 https://reactome.org/PathwayBrowser/#/R-MMU-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Mus musculus 29985 R-MMU-372448 https://reactome.org/PathwayBrowser/#/R-MMU-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Mus musculus 29985 R-MMU-373075 https://reactome.org/PathwayBrowser/#/R-MMU-373075 Metabotropic glutamate receptors bind glutamate IEA Mus musculus 29985 R-MMU-378513 https://reactome.org/PathwayBrowser/#/R-MMU-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Mus musculus 29985 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 29985 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 29985 R-MMU-3928627 https://reactome.org/PathwayBrowser/#/R-MMU-3928627 EPHB phosphorylates TIAM1 IEA Mus musculus 29985 R-MMU-3928645 https://reactome.org/PathwayBrowser/#/R-MMU-3928645 EPHB:NMDAR binds TIAM1 IEA Mus musculus 29985 R-MMU-399711 https://reactome.org/PathwayBrowser/#/R-MMU-399711 Activation of Ca impermeable AMPA receptors IEA Mus musculus 29985 R-MMU-399712 https://reactome.org/PathwayBrowser/#/R-MMU-399712 Activation of Ca permeable AMPA receptors IEA Mus musculus 29985 R-MMU-4093336 https://reactome.org/PathwayBrowser/#/R-MMU-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 29985 R-MMU-420975 https://reactome.org/PathwayBrowser/#/R-MMU-420975 Ca impermeable AMPA receptor ligand binding IEA Mus musculus 29985 R-MMU-420977 https://reactome.org/PathwayBrowser/#/R-MMU-420977 Ca permeable AMPA receptor ligand binding IEA Mus musculus 29985 R-MMU-420980 https://reactome.org/PathwayBrowser/#/R-MMU-420980 Activation of Ca permeable AMPA receptors IEA Mus musculus 29985 R-MMU-428015 https://reactome.org/PathwayBrowser/#/R-MMU-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Mus musculus 29985 R-MMU-428052 https://reactome.org/PathwayBrowser/#/R-MMU-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Mus musculus 29985 R-MMU-432164 https://reactome.org/PathwayBrowser/#/R-MMU-432164 Ca2+ influx into the post-synaptic cell IEA Mus musculus 29985 R-MMU-438037 https://reactome.org/PathwayBrowser/#/R-MMU-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Mus musculus 29985 R-MMU-444705 https://reactome.org/PathwayBrowser/#/R-MMU-444705 T1R1/T1R3 dimer is the umami taste receptor IEA Mus musculus 29985 R-MMU-449715 https://reactome.org/PathwayBrowser/#/R-MMU-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Mus musculus 29985 R-MMU-451283 https://reactome.org/PathwayBrowser/#/R-MMU-451283 kainate receptor binds glutamate IEA Mus musculus 29985 R-MMU-451309 https://reactome.org/PathwayBrowser/#/R-MMU-451309 Edited Kainate Receptor binds glutamate IEA Mus musculus 29985 R-MMU-451310 https://reactome.org/PathwayBrowser/#/R-MMU-451310 Activation of Edited Kainate receptors IEA Mus musculus 29985 R-MMU-451311 https://reactome.org/PathwayBrowser/#/R-MMU-451311 Activation of Ca-permeable Kainate receptors IEA Mus musculus 29985 R-MMU-500708 https://reactome.org/PathwayBrowser/#/R-MMU-500708 GRIK3 homomer binds glutamate IEA Mus musculus 29985 R-MMU-500717 https://reactome.org/PathwayBrowser/#/R-MMU-500717 Activation of GRIK3 homomer IEA Mus musculus 29985 R-MMU-504054 https://reactome.org/PathwayBrowser/#/R-MMU-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Mus musculus 29985 R-MMU-507749 https://reactome.org/PathwayBrowser/#/R-MMU-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Mus musculus 29985 R-MMU-507775 https://reactome.org/PathwayBrowser/#/R-MMU-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Mus musculus 29985 R-MMU-508040 https://reactome.org/PathwayBrowser/#/R-MMU-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Mus musculus 29985 R-MMU-508179 https://reactome.org/PathwayBrowser/#/R-MMU-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Mus musculus 29985 R-MMU-508189 https://reactome.org/PathwayBrowser/#/R-MMU-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Mus musculus 29985 R-MMU-508561 https://reactome.org/PathwayBrowser/#/R-MMU-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Mus musculus 29985 R-MMU-517444 https://reactome.org/PathwayBrowser/#/R-MMU-517444 TAT aminates HPP IEA Mus musculus 29985 R-MMU-5433072 https://reactome.org/PathwayBrowser/#/R-MMU-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Mus musculus 29985 R-MMU-5672965 https://reactome.org/PathwayBrowser/#/R-MMU-5672965 RAS GEFs promote RAS nucleotide exchange IEA Mus musculus 29985 R-MMU-5693783 https://reactome.org/PathwayBrowser/#/R-MMU-5693783 NAALADases hydrolyse NAAG IEA Mus musculus 29985 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 29985 R-MMU-70523 https://reactome.org/PathwayBrowser/#/R-MMU-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Mus musculus 29985 R-MMU-70524 https://reactome.org/PathwayBrowser/#/R-MMU-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Mus musculus 29985 R-MMU-70542 https://reactome.org/PathwayBrowser/#/R-MMU-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Mus musculus 29985 R-MMU-70581 https://reactome.org/PathwayBrowser/#/R-MMU-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Mus musculus 29985 R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Mus musculus 29985 R-MMU-70592 https://reactome.org/PathwayBrowser/#/R-MMU-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Mus musculus 29985 R-MMU-70596 https://reactome.org/PathwayBrowser/#/R-MMU-70596 GOT2 dimer deaminates L-Asp IEA Mus musculus 29985 R-MMU-70599 https://reactome.org/PathwayBrowser/#/R-MMU-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Mus musculus 29985 R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Mus musculus 29985 R-MMU-70606 https://reactome.org/PathwayBrowser/#/R-MMU-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Mus musculus 29985 R-MMU-70609 https://reactome.org/PathwayBrowser/#/R-MMU-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Mus musculus 29985 R-MMU-70613 https://reactome.org/PathwayBrowser/#/R-MMU-70613 GOT2 transaminates OA and L-Glu IEA Mus musculus 29985 R-MMU-70654 https://reactome.org/PathwayBrowser/#/R-MMU-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Mus musculus 29985 R-MMU-70666 https://reactome.org/PathwayBrowser/#/R-MMU-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Mus musculus 29985 R-MMU-70679 https://reactome.org/PathwayBrowser/#/R-MMU-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Mus musculus 29985 R-MMU-70723 https://reactome.org/PathwayBrowser/#/R-MMU-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Mus musculus 29985 R-MMU-70724 https://reactome.org/PathwayBrowser/#/R-MMU-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Mus musculus 29985 R-MMU-70920 https://reactome.org/PathwayBrowser/#/R-MMU-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Mus musculus 29985 R-MMU-70940 https://reactome.org/PathwayBrowser/#/R-MMU-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Mus musculus 29985 R-MMU-70952 https://reactome.org/PathwayBrowser/#/R-MMU-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Mus musculus 29985 R-MMU-71155 https://reactome.org/PathwayBrowser/#/R-MMU-71155 TAT deaminates tyrosine IEA Mus musculus 29985 R-MMU-73577 https://reactome.org/PathwayBrowser/#/R-MMU-73577 CAD hexamer transforms L-Gln to CAP IEA Mus musculus 29985 R-MMU-73647 https://reactome.org/PathwayBrowser/#/R-MMU-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Mus musculus 29985 R-MMU-73792 https://reactome.org/PathwayBrowser/#/R-MMU-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Mus musculus 29985 R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 29985 R-MMU-73815 https://reactome.org/PathwayBrowser/#/R-MMU-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Mus musculus 29985 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 29985 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 29985 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 29985 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 29985 R-MMU-8849878 https://reactome.org/PathwayBrowser/#/R-MMU-8849878 PSD-95 binds NMDA receptor IEA Mus musculus 29985 R-MMU-8849881 https://reactome.org/PathwayBrowser/#/R-MMU-8849881 SALM2 associate with AMPA and NMDA receptors IEA Mus musculus 29985 R-MMU-8849906 https://reactome.org/PathwayBrowser/#/R-MMU-8849906 SALM1 binds NMDA receptor IEA Mus musculus 29985 R-MMU-8865774 https://reactome.org/PathwayBrowser/#/R-MMU-8865774 TTLLs polyglutamylate tubulin IEA Mus musculus 29985 R-MMU-8875623 https://reactome.org/PathwayBrowser/#/R-MMU-8875623 SLC25A18,22 import L-Glu, H+ IEA Mus musculus 29985 R-MMU-888572 https://reactome.org/PathwayBrowser/#/R-MMU-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Mus musculus 29985 R-MMU-888577 https://reactome.org/PathwayBrowser/#/R-MMU-888577 Synthesis of GABA by GAD2 IEA Mus musculus 29985 R-MMU-893583 https://reactome.org/PathwayBrowser/#/R-MMU-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Mus musculus 29985 R-MMU-8942575 https://reactome.org/PathwayBrowser/#/R-MMU-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Mus musculus 29985 R-MMU-8943279 https://reactome.org/PathwayBrowser/#/R-MMU-8943279 GGT dimers hydrolyse GSH IEA Mus musculus 29985 R-MMU-916855 https://reactome.org/PathwayBrowser/#/R-MMU-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Mus musculus 29985 R-MMU-9664156 https://reactome.org/PathwayBrowser/#/R-MMU-9664156 Exocytosis of glutamate from cochlear inner hair cell TAS Mus musculus 29985 R-MMU-9717206 https://reactome.org/PathwayBrowser/#/R-MMU-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Mus musculus 29985 R-MMU-9748957 https://reactome.org/PathwayBrowser/#/R-MMU-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Mus musculus 29985 R-MMU-9753634 https://reactome.org/PathwayBrowser/#/R-MMU-9753634 GGT dimers hydrolyse APAP-SG IEA Mus musculus 29985 R-MMU-977333 https://reactome.org/PathwayBrowser/#/R-MMU-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Mus musculus 29985 R-NUL-8955873 https://reactome.org/PathwayBrowser/#/R-NUL-8955873 Polyglutamylase complex (Ttll1) polyglutamylates alpha subunits of tubulin TAS Homo sapiens 29985 R-PFA-197271 https://reactome.org/PathwayBrowser/#/R-PFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Plasmodium falciparum 29985 R-PFA-449715 https://reactome.org/PathwayBrowser/#/R-PFA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Plasmodium falciparum 29985 R-PFA-504054 https://reactome.org/PathwayBrowser/#/R-PFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Plasmodium falciparum 29985 R-PFA-70581 https://reactome.org/PathwayBrowser/#/R-PFA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Plasmodium falciparum 29985 R-PFA-70592 https://reactome.org/PathwayBrowser/#/R-PFA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Plasmodium falciparum 29985 R-PFA-70599 https://reactome.org/PathwayBrowser/#/R-PFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Plasmodium falciparum 29985 R-PFA-70654 https://reactome.org/PathwayBrowser/#/R-PFA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Plasmodium falciparum 29985 R-PFA-70666 https://reactome.org/PathwayBrowser/#/R-PFA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Plasmodium falciparum 29985 R-PFA-73577 https://reactome.org/PathwayBrowser/#/R-PFA-73577 CAD hexamer transforms L-Gln to CAP IEA Plasmodium falciparum 29985 R-PFA-73647 https://reactome.org/PathwayBrowser/#/R-PFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Plasmodium falciparum 29985 R-PFA-73792 https://reactome.org/PathwayBrowser/#/R-PFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Plasmodium falciparum 29985 R-PFA-8865774 https://reactome.org/PathwayBrowser/#/R-PFA-8865774 TTLLs polyglutamylate tubulin IEA Plasmodium falciparum 29985 R-PFA-9748957 https://reactome.org/PathwayBrowser/#/R-PFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Plasmodium falciparum 29985 R-RNO-1247935 https://reactome.org/PathwayBrowser/#/R-RNO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Rattus norvegicus 29985 R-RNO-174367 https://reactome.org/PathwayBrowser/#/R-RNO-174367 GCL ligates L-Glu to L-Cys IEA Rattus norvegicus 29985 R-RNO-197271 https://reactome.org/PathwayBrowser/#/R-RNO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Rattus norvegicus 29985 R-RNO-197958 https://reactome.org/PathwayBrowser/#/R-RNO-197958 FPGS-2 transforms THF to THFPG IEA Rattus norvegicus 29985 R-RNO-200681 https://reactome.org/PathwayBrowser/#/R-RNO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Rattus norvegicus 29985 R-RNO-200682 https://reactome.org/PathwayBrowser/#/R-RNO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Rattus norvegicus 29985 R-RNO-210404 https://reactome.org/PathwayBrowser/#/R-RNO-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Rattus norvegicus 29985 R-RNO-210426 https://reactome.org/PathwayBrowser/#/R-RNO-210426 Glutamate synaptic vesicle docking and priming IEA Rattus norvegicus 29985 R-RNO-210430 https://reactome.org/PathwayBrowser/#/R-RNO-210430 Release of L-Glutamate at the synapse IEA Rattus norvegicus 29985 R-RNO-210439 https://reactome.org/PathwayBrowser/#/R-RNO-210439 glutamate uptake by astrocytes IEA Rattus norvegicus 29985 R-RNO-210444 https://reactome.org/PathwayBrowser/#/R-RNO-210444 L-Glutamate loading of synaptic vesicle IEA Rattus norvegicus 29985 R-RNO-266046 https://reactome.org/PathwayBrowser/#/R-RNO-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Rattus norvegicus 29985 R-RNO-372448 https://reactome.org/PathwayBrowser/#/R-RNO-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Rattus norvegicus 29985 R-RNO-373075 https://reactome.org/PathwayBrowser/#/R-RNO-373075 Metabotropic glutamate receptors bind glutamate IEA Rattus norvegicus 29985 R-RNO-378513 https://reactome.org/PathwayBrowser/#/R-RNO-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Rattus norvegicus 29985 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 29985 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 29985 R-RNO-3928627 https://reactome.org/PathwayBrowser/#/R-RNO-3928627 EPHB phosphorylates TIAM1 IEA Rattus norvegicus 29985 R-RNO-3928645 https://reactome.org/PathwayBrowser/#/R-RNO-3928645 EPHB:NMDAR binds TIAM1 IEA Rattus norvegicus 29985 R-RNO-399711 https://reactome.org/PathwayBrowser/#/R-RNO-399711 Activation of Ca impermeable AMPA receptors IEA Rattus norvegicus 29985 R-RNO-399712 https://reactome.org/PathwayBrowser/#/R-RNO-399712 Activation of Ca permeable AMPA receptors IEA Rattus norvegicus 29985 R-RNO-4093336 https://reactome.org/PathwayBrowser/#/R-RNO-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 29985 R-RNO-420975 https://reactome.org/PathwayBrowser/#/R-RNO-420975 Ca impermeable AMPA receptor ligand binding IEA Rattus norvegicus 29985 R-RNO-420977 https://reactome.org/PathwayBrowser/#/R-RNO-420977 Ca permeable AMPA receptor ligand binding IEA Rattus norvegicus 29985 R-RNO-420980 https://reactome.org/PathwayBrowser/#/R-RNO-420980 Activation of Ca permeable AMPA receptors IEA Rattus norvegicus 29985 R-RNO-428015 https://reactome.org/PathwayBrowser/#/R-RNO-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Rattus norvegicus 29985 R-RNO-428052 https://reactome.org/PathwayBrowser/#/R-RNO-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Rattus norvegicus 29985 R-RNO-432164 https://reactome.org/PathwayBrowser/#/R-RNO-432164 Ca2+ influx into the post-synaptic cell IEA Rattus norvegicus 29985 R-RNO-438037 https://reactome.org/PathwayBrowser/#/R-RNO-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Rattus norvegicus 29985 R-RNO-444705 https://reactome.org/PathwayBrowser/#/R-RNO-444705 T1R1/T1R3 dimer is the umami taste receptor IEA Rattus norvegicus 29985 R-RNO-449715 https://reactome.org/PathwayBrowser/#/R-RNO-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Rattus norvegicus 29985 R-RNO-451283 https://reactome.org/PathwayBrowser/#/R-RNO-451283 kainate receptor binds glutamate IEA Rattus norvegicus 29985 R-RNO-451309 https://reactome.org/PathwayBrowser/#/R-RNO-451309 Edited Kainate Receptor binds glutamate IEA Rattus norvegicus 29985 R-RNO-451310 https://reactome.org/PathwayBrowser/#/R-RNO-451310 Activation of Edited Kainate receptors IEA Rattus norvegicus 29985 R-RNO-451311 https://reactome.org/PathwayBrowser/#/R-RNO-451311 Activation of Ca-permeable Kainate receptors IEA Rattus norvegicus 29985 R-RNO-500708 https://reactome.org/PathwayBrowser/#/R-RNO-500708 GRIK3 homomer binds glutamate IEA Rattus norvegicus 29985 R-RNO-504054 https://reactome.org/PathwayBrowser/#/R-RNO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Rattus norvegicus 29985 R-RNO-507749 https://reactome.org/PathwayBrowser/#/R-RNO-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Rattus norvegicus 29985 R-RNO-507775 https://reactome.org/PathwayBrowser/#/R-RNO-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Rattus norvegicus 29985 R-RNO-508040 https://reactome.org/PathwayBrowser/#/R-RNO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Rattus norvegicus 29985 R-RNO-508179 https://reactome.org/PathwayBrowser/#/R-RNO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Rattus norvegicus 29985 R-RNO-508189 https://reactome.org/PathwayBrowser/#/R-RNO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Rattus norvegicus 29985 R-RNO-508561 https://reactome.org/PathwayBrowser/#/R-RNO-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Rattus norvegicus 29985 R-RNO-517444 https://reactome.org/PathwayBrowser/#/R-RNO-517444 TAT aminates HPP IEA Rattus norvegicus 29985 R-RNO-5433072 https://reactome.org/PathwayBrowser/#/R-RNO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Rattus norvegicus 29985 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus 29985 R-RNO-5693783 https://reactome.org/PathwayBrowser/#/R-RNO-5693783 NAALADases hydrolyse NAAG IEA Rattus norvegicus 29985 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 29985 R-RNO-70523 https://reactome.org/PathwayBrowser/#/R-RNO-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Rattus norvegicus 29985 R-RNO-70524 https://reactome.org/PathwayBrowser/#/R-RNO-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Rattus norvegicus 29985 R-RNO-70542 https://reactome.org/PathwayBrowser/#/R-RNO-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Rattus norvegicus 29985 R-RNO-70581 https://reactome.org/PathwayBrowser/#/R-RNO-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Rattus norvegicus 29985 R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Rattus norvegicus 29985 R-RNO-70592 https://reactome.org/PathwayBrowser/#/R-RNO-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Rattus norvegicus 29985 R-RNO-70596 https://reactome.org/PathwayBrowser/#/R-RNO-70596 GOT2 dimer deaminates L-Asp IEA Rattus norvegicus 29985 R-RNO-70599 https://reactome.org/PathwayBrowser/#/R-RNO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Rattus norvegicus 29985 R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Rattus norvegicus 29985 R-RNO-70606 https://reactome.org/PathwayBrowser/#/R-RNO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Rattus norvegicus 29985 R-RNO-70609 https://reactome.org/PathwayBrowser/#/R-RNO-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Rattus norvegicus 29985 R-RNO-70613 https://reactome.org/PathwayBrowser/#/R-RNO-70613 GOT2 transaminates OA and L-Glu IEA Rattus norvegicus 29985 R-RNO-70654 https://reactome.org/PathwayBrowser/#/R-RNO-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Rattus norvegicus 29985 R-RNO-70666 https://reactome.org/PathwayBrowser/#/R-RNO-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Rattus norvegicus 29985 R-RNO-70679 https://reactome.org/PathwayBrowser/#/R-RNO-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Rattus norvegicus 29985 R-RNO-70723 https://reactome.org/PathwayBrowser/#/R-RNO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Rattus norvegicus 29985 R-RNO-70724 https://reactome.org/PathwayBrowser/#/R-RNO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Rattus norvegicus 29985 R-RNO-70920 https://reactome.org/PathwayBrowser/#/R-RNO-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Rattus norvegicus 29985 R-RNO-70940 https://reactome.org/PathwayBrowser/#/R-RNO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Rattus norvegicus 29985 R-RNO-70952 https://reactome.org/PathwayBrowser/#/R-RNO-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Rattus norvegicus 29985 R-RNO-71155 https://reactome.org/PathwayBrowser/#/R-RNO-71155 TAT deaminates tyrosine IEA Rattus norvegicus 29985 R-RNO-73577 https://reactome.org/PathwayBrowser/#/R-RNO-73577 CAD hexamer transforms L-Gln to CAP IEA Rattus norvegicus 29985 R-RNO-73647 https://reactome.org/PathwayBrowser/#/R-RNO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Rattus norvegicus 29985 R-RNO-73792 https://reactome.org/PathwayBrowser/#/R-RNO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Rattus norvegicus 29985 R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 29985 R-RNO-73815 https://reactome.org/PathwayBrowser/#/R-RNO-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Rattus norvegicus 29985 R-RNO-8849878 https://reactome.org/PathwayBrowser/#/R-RNO-8849878 PSD-95 binds NMDA receptor IEA Rattus norvegicus 29985 R-RNO-8849881 https://reactome.org/PathwayBrowser/#/R-RNO-8849881 SALM2 associate with AMPA and NMDA receptors IEA Rattus norvegicus 29985 R-RNO-8849906 https://reactome.org/PathwayBrowser/#/R-RNO-8849906 SALM1 binds NMDA receptor IEA Rattus norvegicus 29985 R-RNO-8865774 https://reactome.org/PathwayBrowser/#/R-RNO-8865774 TTLLs polyglutamylate tubulin IEA Rattus norvegicus 29985 R-RNO-8875623 https://reactome.org/PathwayBrowser/#/R-RNO-8875623 SLC25A18,22 import L-Glu, H+ IEA Rattus norvegicus 29985 R-RNO-888572 https://reactome.org/PathwayBrowser/#/R-RNO-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Rattus norvegicus 29985 R-RNO-888577 https://reactome.org/PathwayBrowser/#/R-RNO-888577 Synthesis of GABA by GAD2 IEA Rattus norvegicus 29985 R-RNO-893583 https://reactome.org/PathwayBrowser/#/R-RNO-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Rattus norvegicus 29985 R-RNO-8942575 https://reactome.org/PathwayBrowser/#/R-RNO-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Rattus norvegicus 29985 R-RNO-8943279 https://reactome.org/PathwayBrowser/#/R-RNO-8943279 GGT dimers hydrolyse GSH IEA Rattus norvegicus 29985 R-RNO-9012709 https://reactome.org/PathwayBrowser/#/R-RNO-9012709 Got2:PLXP dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu TAS Rattus norvegicus 29985 R-RNO-916855 https://reactome.org/PathwayBrowser/#/R-RNO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Rattus norvegicus 29985 R-RNO-9612145 https://reactome.org/PathwayBrowser/#/R-RNO-9612145 Src phosphorylates GluN2 (Grin2) subunits of NMDARs TAS Rattus norvegicus 29985 R-RNO-9614350 https://reactome.org/PathwayBrowser/#/R-RNO-9614350 Glycine and glutamate ligands bind Grin1:Grin2a NMDA receptor TAS Rattus norvegicus 29985 R-RNO-9614351 https://reactome.org/PathwayBrowser/#/R-RNO-9614351 Unblocking of Grin1:Grin2 NMDA receptors TAS Rattus norvegicus 29985 R-RNO-9617322 https://reactome.org/PathwayBrowser/#/R-RNO-9617322 Calm1:4xCa2+ binds GluN1:GluN2 (Grin1:Grin2) NMDA receptors and displaces Actn2 TAS Rattus norvegicus 29985 R-RNO-9618659 https://reactome.org/PathwayBrowser/#/R-RNO-9618659 CaMKII binds activated GluN1:GluN2B (Grin1:Grin2b) NMDA receptor TAS Rattus norvegicus 29985 R-RNO-9717206 https://reactome.org/PathwayBrowser/#/R-RNO-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Rattus norvegicus 29985 R-RNO-9737016 https://reactome.org/PathwayBrowser/#/R-RNO-9737016 L-Glutamate binds Grm4 (mGluR4) TAS Rattus norvegicus 29985 R-RNO-9737052 https://reactome.org/PathwayBrowser/#/R-RNO-9737052 L-Glutamate binds Grm1 (mGluR1) TAS Rattus norvegicus 29985 R-RNO-9748957 https://reactome.org/PathwayBrowser/#/R-RNO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Rattus norvegicus 29985 R-RNO-9753634 https://reactome.org/PathwayBrowser/#/R-RNO-9753634 GGT dimers hydrolyse APAP-SG IEA Rattus norvegicus 29985 R-RNO-977333 https://reactome.org/PathwayBrowser/#/R-RNO-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Rattus norvegicus 29985 R-SCE-1247935 https://reactome.org/PathwayBrowser/#/R-SCE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Saccharomyces cerevisiae 29985 R-SCE-197271 https://reactome.org/PathwayBrowser/#/R-SCE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Saccharomyces cerevisiae 29985 R-SCE-197958 https://reactome.org/PathwayBrowser/#/R-SCE-197958 FPGS-2 transforms THF to THFPG IEA Saccharomyces cerevisiae 29985 R-SCE-200681 https://reactome.org/PathwayBrowser/#/R-SCE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Saccharomyces cerevisiae 29985 R-SCE-200682 https://reactome.org/PathwayBrowser/#/R-SCE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Saccharomyces cerevisiae 29985 R-SCE-266046 https://reactome.org/PathwayBrowser/#/R-SCE-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Saccharomyces cerevisiae 29985 R-SCE-372448 https://reactome.org/PathwayBrowser/#/R-SCE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Saccharomyces cerevisiae 29985 R-SCE-449715 https://reactome.org/PathwayBrowser/#/R-SCE-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Saccharomyces cerevisiae 29985 R-SCE-504054 https://reactome.org/PathwayBrowser/#/R-SCE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Saccharomyces cerevisiae 29985 R-SCE-507749 https://reactome.org/PathwayBrowser/#/R-SCE-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Saccharomyces cerevisiae 29985 R-SCE-507775 https://reactome.org/PathwayBrowser/#/R-SCE-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Saccharomyces cerevisiae 29985 R-SCE-508040 https://reactome.org/PathwayBrowser/#/R-SCE-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Saccharomyces cerevisiae 29985 R-SCE-508179 https://reactome.org/PathwayBrowser/#/R-SCE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Saccharomyces cerevisiae 29985 R-SCE-508189 https://reactome.org/PathwayBrowser/#/R-SCE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Saccharomyces cerevisiae 29985 R-SCE-508561 https://reactome.org/PathwayBrowser/#/R-SCE-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Saccharomyces cerevisiae 29985 R-SCE-5433072 https://reactome.org/PathwayBrowser/#/R-SCE-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Saccharomyces cerevisiae 29985 R-SCE-5693783 https://reactome.org/PathwayBrowser/#/R-SCE-5693783 NAALADases hydrolyse NAAG IEA Saccharomyces cerevisiae 29985 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 29985 R-SCE-70523 https://reactome.org/PathwayBrowser/#/R-SCE-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Saccharomyces cerevisiae 29985 R-SCE-70524 https://reactome.org/PathwayBrowser/#/R-SCE-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Saccharomyces cerevisiae 29985 R-SCE-70542 https://reactome.org/PathwayBrowser/#/R-SCE-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Saccharomyces cerevisiae 29985 R-SCE-70581 https://reactome.org/PathwayBrowser/#/R-SCE-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Saccharomyces cerevisiae 29985 R-SCE-70592 https://reactome.org/PathwayBrowser/#/R-SCE-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Saccharomyces cerevisiae 29985 R-SCE-70596 https://reactome.org/PathwayBrowser/#/R-SCE-70596 GOT2 dimer deaminates L-Asp IEA Saccharomyces cerevisiae 29985 R-SCE-70599 https://reactome.org/PathwayBrowser/#/R-SCE-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Saccharomyces cerevisiae 29985 R-SCE-70606 https://reactome.org/PathwayBrowser/#/R-SCE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Saccharomyces cerevisiae 29985 R-SCE-70613 https://reactome.org/PathwayBrowser/#/R-SCE-70613 GOT2 transaminates OA and L-Glu IEA Saccharomyces cerevisiae 29985 R-SCE-70654 https://reactome.org/PathwayBrowser/#/R-SCE-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Saccharomyces cerevisiae 29985 R-SCE-70666 https://reactome.org/PathwayBrowser/#/R-SCE-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Saccharomyces cerevisiae 29985 R-SCE-70723 https://reactome.org/PathwayBrowser/#/R-SCE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Saccharomyces cerevisiae 29985 R-SCE-70724 https://reactome.org/PathwayBrowser/#/R-SCE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Saccharomyces cerevisiae 29985 R-SCE-70940 https://reactome.org/PathwayBrowser/#/R-SCE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Saccharomyces cerevisiae 29985 R-SCE-70952 https://reactome.org/PathwayBrowser/#/R-SCE-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Saccharomyces cerevisiae 29985 R-SCE-73577 https://reactome.org/PathwayBrowser/#/R-SCE-73577 CAD hexamer transforms L-Gln to CAP IEA Saccharomyces cerevisiae 29985 R-SCE-73647 https://reactome.org/PathwayBrowser/#/R-SCE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Saccharomyces cerevisiae 29985 R-SCE-73792 https://reactome.org/PathwayBrowser/#/R-SCE-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Saccharomyces cerevisiae 29985 R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 29985 R-SCE-8875623 https://reactome.org/PathwayBrowser/#/R-SCE-8875623 SLC25A18,22 import L-Glu, H+ IEA Saccharomyces cerevisiae 29985 R-SCE-893583 https://reactome.org/PathwayBrowser/#/R-SCE-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Saccharomyces cerevisiae 29985 R-SCE-8943279 https://reactome.org/PathwayBrowser/#/R-SCE-8943279 GGT dimers hydrolyse GSH IEA Saccharomyces cerevisiae 29985 R-SCE-916855 https://reactome.org/PathwayBrowser/#/R-SCE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Saccharomyces cerevisiae 29985 R-SCE-9748957 https://reactome.org/PathwayBrowser/#/R-SCE-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Saccharomyces cerevisiae 29985 R-SCE-9753634 https://reactome.org/PathwayBrowser/#/R-SCE-9753634 GGT dimers hydrolyse APAP-SG IEA Saccharomyces cerevisiae 29985 R-SCE-977333 https://reactome.org/PathwayBrowser/#/R-SCE-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Saccharomyces cerevisiae 29985 R-SPO-1247935 https://reactome.org/PathwayBrowser/#/R-SPO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Schizosaccharomyces pombe 29985 R-SPO-174367 https://reactome.org/PathwayBrowser/#/R-SPO-174367 GCL ligates L-Glu to L-Cys IEA Schizosaccharomyces pombe 29985 R-SPO-197271 https://reactome.org/PathwayBrowser/#/R-SPO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Schizosaccharomyces pombe 29985 R-SPO-197958 https://reactome.org/PathwayBrowser/#/R-SPO-197958 FPGS-2 transforms THF to THFPG IEA Schizosaccharomyces pombe 29985 R-SPO-200681 https://reactome.org/PathwayBrowser/#/R-SPO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Schizosaccharomyces pombe 29985 R-SPO-200682 https://reactome.org/PathwayBrowser/#/R-SPO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Schizosaccharomyces pombe 29985 R-SPO-266046 https://reactome.org/PathwayBrowser/#/R-SPO-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Schizosaccharomyces pombe 29985 R-SPO-449715 https://reactome.org/PathwayBrowser/#/R-SPO-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Schizosaccharomyces pombe 29985 R-SPO-504054 https://reactome.org/PathwayBrowser/#/R-SPO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Schizosaccharomyces pombe 29985 R-SPO-508040 https://reactome.org/PathwayBrowser/#/R-SPO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Schizosaccharomyces pombe 29985 R-SPO-508179 https://reactome.org/PathwayBrowser/#/R-SPO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Schizosaccharomyces pombe 29985 R-SPO-508189 https://reactome.org/PathwayBrowser/#/R-SPO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Schizosaccharomyces pombe 29985 R-SPO-508561 https://reactome.org/PathwayBrowser/#/R-SPO-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Schizosaccharomyces pombe 29985 R-SPO-5433072 https://reactome.org/PathwayBrowser/#/R-SPO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Schizosaccharomyces pombe 29985 R-SPO-5693783 https://reactome.org/PathwayBrowser/#/R-SPO-5693783 NAALADases hydrolyse NAAG IEA Schizosaccharomyces pombe 29985 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 29985 R-SPO-70542 https://reactome.org/PathwayBrowser/#/R-SPO-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Schizosaccharomyces pombe 29985 R-SPO-70581 https://reactome.org/PathwayBrowser/#/R-SPO-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Schizosaccharomyces pombe 29985 R-SPO-70592 https://reactome.org/PathwayBrowser/#/R-SPO-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Schizosaccharomyces pombe 29985 R-SPO-70596 https://reactome.org/PathwayBrowser/#/R-SPO-70596 GOT2 dimer deaminates L-Asp IEA Schizosaccharomyces pombe 29985 R-SPO-70599 https://reactome.org/PathwayBrowser/#/R-SPO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Schizosaccharomyces pombe 29985 R-SPO-70606 https://reactome.org/PathwayBrowser/#/R-SPO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Schizosaccharomyces pombe 29985 R-SPO-70613 https://reactome.org/PathwayBrowser/#/R-SPO-70613 GOT2 transaminates OA and L-Glu IEA Schizosaccharomyces pombe 29985 R-SPO-70654 https://reactome.org/PathwayBrowser/#/R-SPO-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Schizosaccharomyces pombe 29985 R-SPO-70666 https://reactome.org/PathwayBrowser/#/R-SPO-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Schizosaccharomyces pombe 29985 R-SPO-70723 https://reactome.org/PathwayBrowser/#/R-SPO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Schizosaccharomyces pombe 29985 R-SPO-70724 https://reactome.org/PathwayBrowser/#/R-SPO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Schizosaccharomyces pombe 29985 R-SPO-70940 https://reactome.org/PathwayBrowser/#/R-SPO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Schizosaccharomyces pombe 29985 R-SPO-70952 https://reactome.org/PathwayBrowser/#/R-SPO-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Schizosaccharomyces pombe 29985 R-SPO-73577 https://reactome.org/PathwayBrowser/#/R-SPO-73577 CAD hexamer transforms L-Gln to CAP IEA Schizosaccharomyces pombe 29985 R-SPO-73647 https://reactome.org/PathwayBrowser/#/R-SPO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Schizosaccharomyces pombe 29985 R-SPO-73792 https://reactome.org/PathwayBrowser/#/R-SPO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Schizosaccharomyces pombe 29985 R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 29985 R-SPO-893583 https://reactome.org/PathwayBrowser/#/R-SPO-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Schizosaccharomyces pombe 29985 R-SPO-8943279 https://reactome.org/PathwayBrowser/#/R-SPO-8943279 GGT dimers hydrolyse GSH IEA Schizosaccharomyces pombe 29985 R-SPO-916855 https://reactome.org/PathwayBrowser/#/R-SPO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Schizosaccharomyces pombe 29985 R-SPO-9748957 https://reactome.org/PathwayBrowser/#/R-SPO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Schizosaccharomyces pombe 29985 R-SPO-9753634 https://reactome.org/PathwayBrowser/#/R-SPO-9753634 GGT dimers hydrolyse APAP-SG IEA Schizosaccharomyces pombe 29985 R-SPO-977333 https://reactome.org/PathwayBrowser/#/R-SPO-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Schizosaccharomyces pombe 29985 R-SSC-1247935 https://reactome.org/PathwayBrowser/#/R-SSC-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Sus scrofa 29985 R-SSC-174367 https://reactome.org/PathwayBrowser/#/R-SSC-174367 GCL ligates L-Glu to L-Cys IEA Sus scrofa 29985 R-SSC-197271 https://reactome.org/PathwayBrowser/#/R-SSC-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Sus scrofa 29985 R-SSC-197958 https://reactome.org/PathwayBrowser/#/R-SSC-197958 FPGS-2 transforms THF to THFPG IEA Sus scrofa 29985 R-SSC-200681 https://reactome.org/PathwayBrowser/#/R-SSC-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Sus scrofa 29985 R-SSC-200682 https://reactome.org/PathwayBrowser/#/R-SSC-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Sus scrofa 29985 R-SSC-210404 https://reactome.org/PathwayBrowser/#/R-SSC-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Sus scrofa 29985 R-SSC-210426 https://reactome.org/PathwayBrowser/#/R-SSC-210426 Glutamate synaptic vesicle docking and priming IEA Sus scrofa 29985 R-SSC-210430 https://reactome.org/PathwayBrowser/#/R-SSC-210430 Release of L-Glutamate at the synapse IEA Sus scrofa 29985 R-SSC-210439 https://reactome.org/PathwayBrowser/#/R-SSC-210439 glutamate uptake by astrocytes IEA Sus scrofa 29985 R-SSC-210444 https://reactome.org/PathwayBrowser/#/R-SSC-210444 L-Glutamate loading of synaptic vesicle IEA Sus scrofa 29985 R-SSC-266046 https://reactome.org/PathwayBrowser/#/R-SSC-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Sus scrofa 29985 R-SSC-372448 https://reactome.org/PathwayBrowser/#/R-SSC-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Sus scrofa 29985 R-SSC-373075 https://reactome.org/PathwayBrowser/#/R-SSC-373075 Metabotropic glutamate receptors bind glutamate IEA Sus scrofa 29985 R-SSC-378513 https://reactome.org/PathwayBrowser/#/R-SSC-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Sus scrofa 29985 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 29985 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 29985 R-SSC-3928627 https://reactome.org/PathwayBrowser/#/R-SSC-3928627 EPHB phosphorylates TIAM1 IEA Sus scrofa 29985 R-SSC-3928645 https://reactome.org/PathwayBrowser/#/R-SSC-3928645 EPHB:NMDAR binds TIAM1 IEA Sus scrofa 29985 R-SSC-399711 https://reactome.org/PathwayBrowser/#/R-SSC-399711 Activation of Ca impermeable AMPA receptors IEA Sus scrofa 29985 R-SSC-399712 https://reactome.org/PathwayBrowser/#/R-SSC-399712 Activation of Ca permeable AMPA receptors IEA Sus scrofa 29985 R-SSC-4093336 https://reactome.org/PathwayBrowser/#/R-SSC-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa 29985 R-SSC-420975 https://reactome.org/PathwayBrowser/#/R-SSC-420975 Ca impermeable AMPA receptor ligand binding IEA Sus scrofa 29985 R-SSC-420977 https://reactome.org/PathwayBrowser/#/R-SSC-420977 Ca permeable AMPA receptor ligand binding IEA Sus scrofa 29985 R-SSC-420980 https://reactome.org/PathwayBrowser/#/R-SSC-420980 Activation of Ca permeable AMPA receptors IEA Sus scrofa 29985 R-SSC-428015 https://reactome.org/PathwayBrowser/#/R-SSC-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Sus scrofa 29985 R-SSC-428052 https://reactome.org/PathwayBrowser/#/R-SSC-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Sus scrofa 29985 R-SSC-432164 https://reactome.org/PathwayBrowser/#/R-SSC-432164 Ca2+ influx into the post-synaptic cell IEA Sus scrofa 29985 R-SSC-438037 https://reactome.org/PathwayBrowser/#/R-SSC-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Sus scrofa 29985 R-SSC-444705 https://reactome.org/PathwayBrowser/#/R-SSC-444705 T1R1/T1R3 dimer is the umami taste receptor IEA Sus scrofa 29985 R-SSC-449715 https://reactome.org/PathwayBrowser/#/R-SSC-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Sus scrofa 29985 R-SSC-451283 https://reactome.org/PathwayBrowser/#/R-SSC-451283 kainate receptor binds glutamate IEA Sus scrofa 29985 R-SSC-451309 https://reactome.org/PathwayBrowser/#/R-SSC-451309 Edited Kainate Receptor binds glutamate IEA Sus scrofa 29985 R-SSC-451310 https://reactome.org/PathwayBrowser/#/R-SSC-451310 Activation of Edited Kainate receptors IEA Sus scrofa 29985 R-SSC-451311 https://reactome.org/PathwayBrowser/#/R-SSC-451311 Activation of Ca-permeable Kainate receptors IEA Sus scrofa 29985 R-SSC-500708 https://reactome.org/PathwayBrowser/#/R-SSC-500708 GRIK3 homomer binds glutamate IEA Sus scrofa 29985 R-SSC-500717 https://reactome.org/PathwayBrowser/#/R-SSC-500717 Activation of GRIK3 homomer IEA Sus scrofa 29985 R-SSC-504054 https://reactome.org/PathwayBrowser/#/R-SSC-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Sus scrofa 29985 R-SSC-507749 https://reactome.org/PathwayBrowser/#/R-SSC-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Sus scrofa 29985 R-SSC-507775 https://reactome.org/PathwayBrowser/#/R-SSC-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Sus scrofa 29985 R-SSC-508040 https://reactome.org/PathwayBrowser/#/R-SSC-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Sus scrofa 29985 R-SSC-508179 https://reactome.org/PathwayBrowser/#/R-SSC-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Sus scrofa 29985 R-SSC-508189 https://reactome.org/PathwayBrowser/#/R-SSC-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Sus scrofa 29985 R-SSC-508561 https://reactome.org/PathwayBrowser/#/R-SSC-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Sus scrofa 29985 R-SSC-517444 https://reactome.org/PathwayBrowser/#/R-SSC-517444 TAT aminates HPP IEA Sus scrofa 29985 R-SSC-5433072 https://reactome.org/PathwayBrowser/#/R-SSC-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Sus scrofa 29985 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa 29985 R-SSC-5693783 https://reactome.org/PathwayBrowser/#/R-SSC-5693783 NAALADases hydrolyse NAAG IEA Sus scrofa 29985 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 29985 R-SSC-70523 https://reactome.org/PathwayBrowser/#/R-SSC-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Sus scrofa 29985 R-SSC-70524 https://reactome.org/PathwayBrowser/#/R-SSC-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Sus scrofa 29985 R-SSC-70542 https://reactome.org/PathwayBrowser/#/R-SSC-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Sus scrofa 29985 R-SSC-70581 https://reactome.org/PathwayBrowser/#/R-SSC-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Sus scrofa 29985 R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Sus scrofa 29985 R-SSC-70592 https://reactome.org/PathwayBrowser/#/R-SSC-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Sus scrofa 29985 R-SSC-70596 https://reactome.org/PathwayBrowser/#/R-SSC-70596 GOT2 dimer deaminates L-Asp IEA Sus scrofa 29985 R-SSC-70599 https://reactome.org/PathwayBrowser/#/R-SSC-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Sus scrofa 29985 R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Sus scrofa 29985 R-SSC-70606 https://reactome.org/PathwayBrowser/#/R-SSC-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Sus scrofa 29985 R-SSC-70609 https://reactome.org/PathwayBrowser/#/R-SSC-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Sus scrofa 29985 R-SSC-70613 https://reactome.org/PathwayBrowser/#/R-SSC-70613 GOT2 transaminates OA and L-Glu IEA Sus scrofa 29985 R-SSC-70654 https://reactome.org/PathwayBrowser/#/R-SSC-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Sus scrofa 29985 R-SSC-70666 https://reactome.org/PathwayBrowser/#/R-SSC-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Sus scrofa 29985 R-SSC-70679 https://reactome.org/PathwayBrowser/#/R-SSC-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Sus scrofa 29985 R-SSC-70723 https://reactome.org/PathwayBrowser/#/R-SSC-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Sus scrofa 29985 R-SSC-70724 https://reactome.org/PathwayBrowser/#/R-SSC-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Sus scrofa 29985 R-SSC-70920 https://reactome.org/PathwayBrowser/#/R-SSC-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Sus scrofa 29985 R-SSC-70940 https://reactome.org/PathwayBrowser/#/R-SSC-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Sus scrofa 29985 R-SSC-70952 https://reactome.org/PathwayBrowser/#/R-SSC-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Sus scrofa 29985 R-SSC-71155 https://reactome.org/PathwayBrowser/#/R-SSC-71155 TAT deaminates tyrosine IEA Sus scrofa 29985 R-SSC-73577 https://reactome.org/PathwayBrowser/#/R-SSC-73577 CAD hexamer transforms L-Gln to CAP IEA Sus scrofa 29985 R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa 29985 R-SSC-73792 https://reactome.org/PathwayBrowser/#/R-SSC-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Sus scrofa 29985 R-SSC-73815 https://reactome.org/PathwayBrowser/#/R-SSC-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Sus scrofa 29985 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 29985 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 29985 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 29985 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 29985 R-SSC-8849878 https://reactome.org/PathwayBrowser/#/R-SSC-8849878 PSD-95 binds NMDA receptor IEA Sus scrofa 29985 R-SSC-8849906 https://reactome.org/PathwayBrowser/#/R-SSC-8849906 SALM1 binds NMDA receptor IEA Sus scrofa 29985 R-SSC-8865774 https://reactome.org/PathwayBrowser/#/R-SSC-8865774 TTLLs polyglutamylate tubulin IEA Sus scrofa 29985 R-SSC-8875623 https://reactome.org/PathwayBrowser/#/R-SSC-8875623 SLC25A18,22 import L-Glu, H+ IEA Sus scrofa 29985 R-SSC-888572 https://reactome.org/PathwayBrowser/#/R-SSC-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Sus scrofa 29985 R-SSC-888577 https://reactome.org/PathwayBrowser/#/R-SSC-888577 Synthesis of GABA by GAD2 IEA Sus scrofa 29985 R-SSC-893583 https://reactome.org/PathwayBrowser/#/R-SSC-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Sus scrofa 29985 R-SSC-8942575 https://reactome.org/PathwayBrowser/#/R-SSC-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Sus scrofa 29985 R-SSC-8943279 https://reactome.org/PathwayBrowser/#/R-SSC-8943279 GGT dimers hydrolyse GSH IEA Sus scrofa 29985 R-SSC-916855 https://reactome.org/PathwayBrowser/#/R-SSC-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Sus scrofa 29985 R-SSC-9717206 https://reactome.org/PathwayBrowser/#/R-SSC-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Sus scrofa 29985 R-SSC-9748957 https://reactome.org/PathwayBrowser/#/R-SSC-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Sus scrofa 29985 R-SSC-9753634 https://reactome.org/PathwayBrowser/#/R-SSC-9753634 GGT dimers hydrolyse APAP-SG IEA Sus scrofa 29985 R-SSC-977333 https://reactome.org/PathwayBrowser/#/R-SSC-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Sus scrofa 29985 R-XTR-1247935 https://reactome.org/PathwayBrowser/#/R-XTR-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Xenopus tropicalis 29985 R-XTR-174367 https://reactome.org/PathwayBrowser/#/R-XTR-174367 GCL ligates L-Glu to L-Cys IEA Xenopus tropicalis 29985 R-XTR-197958 https://reactome.org/PathwayBrowser/#/R-XTR-197958 FPGS-2 transforms THF to THFPG IEA Xenopus tropicalis 29985 R-XTR-200681 https://reactome.org/PathwayBrowser/#/R-XTR-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Xenopus tropicalis 29985 R-XTR-200682 https://reactome.org/PathwayBrowser/#/R-XTR-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Xenopus tropicalis 29985 R-XTR-210404 https://reactome.org/PathwayBrowser/#/R-XTR-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Xenopus tropicalis 29985 R-XTR-210439 https://reactome.org/PathwayBrowser/#/R-XTR-210439 glutamate uptake by astrocytes IEA Xenopus tropicalis 29985 R-XTR-210444 https://reactome.org/PathwayBrowser/#/R-XTR-210444 L-Glutamate loading of synaptic vesicle IEA Xenopus tropicalis 29985 R-XTR-372448 https://reactome.org/PathwayBrowser/#/R-XTR-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Xenopus tropicalis 29985 R-XTR-373075 https://reactome.org/PathwayBrowser/#/R-XTR-373075 Metabotropic glutamate receptors bind glutamate IEA Xenopus tropicalis 29985 R-XTR-378513 https://reactome.org/PathwayBrowser/#/R-XTR-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Xenopus tropicalis 29985 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 29985 R-XTR-3928627 https://reactome.org/PathwayBrowser/#/R-XTR-3928627 EPHB phosphorylates TIAM1 IEA Xenopus tropicalis 29985 R-XTR-3928645 https://reactome.org/PathwayBrowser/#/R-XTR-3928645 EPHB:NMDAR binds TIAM1 IEA Xenopus tropicalis 29985 R-XTR-4093336 https://reactome.org/PathwayBrowser/#/R-XTR-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Xenopus tropicalis 29985 R-XTR-428015 https://reactome.org/PathwayBrowser/#/R-XTR-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29985 R-XTR-428052 https://reactome.org/PathwayBrowser/#/R-XTR-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Xenopus tropicalis 29985 R-XTR-432164 https://reactome.org/PathwayBrowser/#/R-XTR-432164 Ca2+ influx into the post-synaptic cell IEA Xenopus tropicalis 29985 R-XTR-449715 https://reactome.org/PathwayBrowser/#/R-XTR-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Xenopus tropicalis 29985 R-XTR-500708 https://reactome.org/PathwayBrowser/#/R-XTR-500708 GRIK3 homomer binds glutamate IEA Xenopus tropicalis 29985 R-XTR-500717 https://reactome.org/PathwayBrowser/#/R-XTR-500717 Activation of GRIK3 homomer IEA Xenopus tropicalis 29985 R-XTR-507749 https://reactome.org/PathwayBrowser/#/R-XTR-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Xenopus tropicalis 29985 R-XTR-507775 https://reactome.org/PathwayBrowser/#/R-XTR-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Xenopus tropicalis 29985 R-XTR-508040 https://reactome.org/PathwayBrowser/#/R-XTR-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Xenopus tropicalis 29985 R-XTR-508179 https://reactome.org/PathwayBrowser/#/R-XTR-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Xenopus tropicalis 29985 R-XTR-508189 https://reactome.org/PathwayBrowser/#/R-XTR-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Xenopus tropicalis 29985 R-XTR-508561 https://reactome.org/PathwayBrowser/#/R-XTR-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Xenopus tropicalis 29985 R-XTR-517444 https://reactome.org/PathwayBrowser/#/R-XTR-517444 TAT aminates HPP IEA Xenopus tropicalis 29985 R-XTR-5693783 https://reactome.org/PathwayBrowser/#/R-XTR-5693783 NAALADases hydrolyse NAAG IEA Xenopus tropicalis 29985 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 29985 R-XTR-70523 https://reactome.org/PathwayBrowser/#/R-XTR-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Xenopus tropicalis 29985 R-XTR-70524 https://reactome.org/PathwayBrowser/#/R-XTR-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Xenopus tropicalis 29985 R-XTR-70542 https://reactome.org/PathwayBrowser/#/R-XTR-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Xenopus tropicalis 29985 R-XTR-70581 https://reactome.org/PathwayBrowser/#/R-XTR-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Xenopus tropicalis 29985 R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Xenopus tropicalis 29985 R-XTR-70592 https://reactome.org/PathwayBrowser/#/R-XTR-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Xenopus tropicalis 29985 R-XTR-70596 https://reactome.org/PathwayBrowser/#/R-XTR-70596 GOT2 dimer deaminates L-Asp IEA Xenopus tropicalis 29985 R-XTR-70599 https://reactome.org/PathwayBrowser/#/R-XTR-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Xenopus tropicalis 29985 R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Xenopus tropicalis 29985 R-XTR-70606 https://reactome.org/PathwayBrowser/#/R-XTR-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Xenopus tropicalis 29985 R-XTR-70609 https://reactome.org/PathwayBrowser/#/R-XTR-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Xenopus tropicalis 29985 R-XTR-70613 https://reactome.org/PathwayBrowser/#/R-XTR-70613 GOT2 transaminates OA and L-Glu IEA Xenopus tropicalis 29985 R-XTR-70654 https://reactome.org/PathwayBrowser/#/R-XTR-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Xenopus tropicalis 29985 R-XTR-70666 https://reactome.org/PathwayBrowser/#/R-XTR-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Xenopus tropicalis 29985 R-XTR-70679 https://reactome.org/PathwayBrowser/#/R-XTR-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Xenopus tropicalis 29985 R-XTR-70723 https://reactome.org/PathwayBrowser/#/R-XTR-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Xenopus tropicalis 29985 R-XTR-70724 https://reactome.org/PathwayBrowser/#/R-XTR-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Xenopus tropicalis 29985 R-XTR-70920 https://reactome.org/PathwayBrowser/#/R-XTR-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Xenopus tropicalis 29985 R-XTR-70940 https://reactome.org/PathwayBrowser/#/R-XTR-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Xenopus tropicalis 29985 R-XTR-70952 https://reactome.org/PathwayBrowser/#/R-XTR-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Xenopus tropicalis 29985 R-XTR-71155 https://reactome.org/PathwayBrowser/#/R-XTR-71155 TAT deaminates tyrosine IEA Xenopus tropicalis 29985 R-XTR-73577 https://reactome.org/PathwayBrowser/#/R-XTR-73577 CAD hexamer transforms L-Gln to CAP IEA Xenopus tropicalis 29985 R-XTR-73792 https://reactome.org/PathwayBrowser/#/R-XTR-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Xenopus tropicalis 29985 R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 29985 R-XTR-73815 https://reactome.org/PathwayBrowser/#/R-XTR-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Xenopus tropicalis 29985 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 29985 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 29985 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 29985 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 29985 R-XTR-8849881 https://reactome.org/PathwayBrowser/#/R-XTR-8849881 SALM2 associate with AMPA and NMDA receptors IEA Xenopus tropicalis 29985 R-XTR-8865774 https://reactome.org/PathwayBrowser/#/R-XTR-8865774 TTLLs polyglutamylate tubulin IEA Xenopus tropicalis 29985 R-XTR-8875623 https://reactome.org/PathwayBrowser/#/R-XTR-8875623 SLC25A18,22 import L-Glu, H+ IEA Xenopus tropicalis 29985 R-XTR-888572 https://reactome.org/PathwayBrowser/#/R-XTR-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Xenopus tropicalis 29985 R-XTR-888577 https://reactome.org/PathwayBrowser/#/R-XTR-888577 Synthesis of GABA by GAD2 IEA Xenopus tropicalis 29985 R-XTR-893583 https://reactome.org/PathwayBrowser/#/R-XTR-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Xenopus tropicalis 29985 R-XTR-8942575 https://reactome.org/PathwayBrowser/#/R-XTR-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Xenopus tropicalis 29985 R-XTR-916855 https://reactome.org/PathwayBrowser/#/R-XTR-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Xenopus tropicalis 29985 R-XTR-9748957 https://reactome.org/PathwayBrowser/#/R-XTR-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Xenopus tropicalis 29985 R-XTR-977333 https://reactome.org/PathwayBrowser/#/R-XTR-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Xenopus tropicalis 29991 R-BTA-111524 https://reactome.org/PathwayBrowser/#/R-BTA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Bos taurus 29991 R-BTA-1678854 https://reactome.org/PathwayBrowser/#/R-BTA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Bos taurus 29991 R-BTA-372448 https://reactome.org/PathwayBrowser/#/R-BTA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Bos taurus 29991 R-BTA-428015 https://reactome.org/PathwayBrowser/#/R-BTA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Bos taurus 29991 R-BTA-5691507 https://reactome.org/PathwayBrowser/#/R-BTA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Bos taurus 29991 R-BTA-5696365 https://reactome.org/PathwayBrowser/#/R-BTA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Bos taurus 29991 R-BTA-6784393 https://reactome.org/PathwayBrowser/#/R-BTA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Bos taurus 29991 R-BTA-6787757 https://reactome.org/PathwayBrowser/#/R-BTA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Bos taurus 29991 R-BTA-6797627 https://reactome.org/PathwayBrowser/#/R-BTA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Bos taurus 29991 R-BTA-70577 https://reactome.org/PathwayBrowser/#/R-BTA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Bos taurus 29991 R-BTA-70581 https://reactome.org/PathwayBrowser/#/R-BTA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Bos taurus 29991 R-BTA-70592 https://reactome.org/PathwayBrowser/#/R-BTA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Bos taurus 29991 R-BTA-70596 https://reactome.org/PathwayBrowser/#/R-BTA-70596 GOT2 dimer deaminates L-Asp IEA Bos taurus 29991 R-BTA-70599 https://reactome.org/PathwayBrowser/#/R-BTA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Bos taurus 29991 R-BTA-70613 https://reactome.org/PathwayBrowser/#/R-BTA-70613 GOT2 transaminates OA and L-Glu IEA Bos taurus 29991 R-BTA-73573 https://reactome.org/PathwayBrowser/#/R-BTA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Bos taurus 29991 R-BTA-73805 https://reactome.org/PathwayBrowser/#/R-BTA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Bos taurus 29991 R-BTA-8954468 https://reactome.org/PathwayBrowser/#/R-BTA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Bos taurus 29991 R-BTA-9717206 https://reactome.org/PathwayBrowser/#/R-BTA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Bos taurus 29991 R-CEL-111524 https://reactome.org/PathwayBrowser/#/R-CEL-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Caenorhabditis elegans 29991 R-CEL-1678854 https://reactome.org/PathwayBrowser/#/R-CEL-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Caenorhabditis elegans 29991 R-CEL-372448 https://reactome.org/PathwayBrowser/#/R-CEL-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Caenorhabditis elegans 29991 R-CEL-428015 https://reactome.org/PathwayBrowser/#/R-CEL-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 29991 R-CEL-6784393 https://reactome.org/PathwayBrowser/#/R-CEL-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Caenorhabditis elegans 29991 R-CEL-6797627 https://reactome.org/PathwayBrowser/#/R-CEL-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Caenorhabditis elegans 29991 R-CEL-70581 https://reactome.org/PathwayBrowser/#/R-CEL-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Caenorhabditis elegans 29991 R-CEL-70592 https://reactome.org/PathwayBrowser/#/R-CEL-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Caenorhabditis elegans 29991 R-CEL-70596 https://reactome.org/PathwayBrowser/#/R-CEL-70596 GOT2 dimer deaminates L-Asp IEA Caenorhabditis elegans 29991 R-CEL-70599 https://reactome.org/PathwayBrowser/#/R-CEL-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Caenorhabditis elegans 29991 R-CEL-70613 https://reactome.org/PathwayBrowser/#/R-CEL-70613 GOT2 transaminates OA and L-Glu IEA Caenorhabditis elegans 29991 R-CEL-73573 https://reactome.org/PathwayBrowser/#/R-CEL-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Caenorhabditis elegans 29991 R-CEL-73805 https://reactome.org/PathwayBrowser/#/R-CEL-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Caenorhabditis elegans 29991 R-CFA-111524 https://reactome.org/PathwayBrowser/#/R-CFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Canis familiaris 29991 R-CFA-1678854 https://reactome.org/PathwayBrowser/#/R-CFA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Canis familiaris 29991 R-CFA-372448 https://reactome.org/PathwayBrowser/#/R-CFA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Canis familiaris 29991 R-CFA-428015 https://reactome.org/PathwayBrowser/#/R-CFA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Canis familiaris 29991 R-CFA-5691507 https://reactome.org/PathwayBrowser/#/R-CFA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Canis familiaris 29991 R-CFA-5696365 https://reactome.org/PathwayBrowser/#/R-CFA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Canis familiaris 29991 R-CFA-6784393 https://reactome.org/PathwayBrowser/#/R-CFA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Canis familiaris 29991 R-CFA-6787757 https://reactome.org/PathwayBrowser/#/R-CFA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Canis familiaris 29991 R-CFA-6797627 https://reactome.org/PathwayBrowser/#/R-CFA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Canis familiaris 29991 R-CFA-70577 https://reactome.org/PathwayBrowser/#/R-CFA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Canis familiaris 29991 R-CFA-70581 https://reactome.org/PathwayBrowser/#/R-CFA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Canis familiaris 29991 R-CFA-70592 https://reactome.org/PathwayBrowser/#/R-CFA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Canis familiaris 29991 R-CFA-70596 https://reactome.org/PathwayBrowser/#/R-CFA-70596 GOT2 dimer deaminates L-Asp IEA Canis familiaris 29991 R-CFA-70599 https://reactome.org/PathwayBrowser/#/R-CFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Canis familiaris 29991 R-CFA-70613 https://reactome.org/PathwayBrowser/#/R-CFA-70613 GOT2 transaminates OA and L-Glu IEA Canis familiaris 29991 R-CFA-73573 https://reactome.org/PathwayBrowser/#/R-CFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Canis familiaris 29991 R-CFA-73805 https://reactome.org/PathwayBrowser/#/R-CFA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Canis familiaris 29991 R-CFA-8954468 https://reactome.org/PathwayBrowser/#/R-CFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Canis familiaris 29991 R-CFA-9717206 https://reactome.org/PathwayBrowser/#/R-CFA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Canis familiaris 29991 R-DDI-111524 https://reactome.org/PathwayBrowser/#/R-DDI-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Dictyostelium discoideum 29991 R-DDI-372448 https://reactome.org/PathwayBrowser/#/R-DDI-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Dictyostelium discoideum 29991 R-DDI-6784393 https://reactome.org/PathwayBrowser/#/R-DDI-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Dictyostelium discoideum 29991 R-DDI-6797627 https://reactome.org/PathwayBrowser/#/R-DDI-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Dictyostelium discoideum 29991 R-DDI-70596 https://reactome.org/PathwayBrowser/#/R-DDI-70596 GOT2 dimer deaminates L-Asp IEA Dictyostelium discoideum 29991 R-DDI-70599 https://reactome.org/PathwayBrowser/#/R-DDI-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Dictyostelium discoideum 29991 R-DDI-70613 https://reactome.org/PathwayBrowser/#/R-DDI-70613 GOT2 transaminates OA and L-Glu IEA Dictyostelium discoideum 29991 R-DDI-73573 https://reactome.org/PathwayBrowser/#/R-DDI-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Dictyostelium discoideum 29991 R-DDI-8954468 https://reactome.org/PathwayBrowser/#/R-DDI-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Dictyostelium discoideum 29991 R-DME-111524 https://reactome.org/PathwayBrowser/#/R-DME-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Drosophila melanogaster 29991 R-DME-1678854 https://reactome.org/PathwayBrowser/#/R-DME-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Drosophila melanogaster 29991 R-DME-372448 https://reactome.org/PathwayBrowser/#/R-DME-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Drosophila melanogaster 29991 R-DME-428015 https://reactome.org/PathwayBrowser/#/R-DME-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Drosophila melanogaster 29991 R-DME-5696365 https://reactome.org/PathwayBrowser/#/R-DME-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Drosophila melanogaster 29991 R-DME-6784393 https://reactome.org/PathwayBrowser/#/R-DME-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Drosophila melanogaster 29991 R-DME-6787757 https://reactome.org/PathwayBrowser/#/R-DME-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Drosophila melanogaster 29991 R-DME-6797627 https://reactome.org/PathwayBrowser/#/R-DME-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Drosophila melanogaster 29991 R-DME-70581 https://reactome.org/PathwayBrowser/#/R-DME-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Drosophila melanogaster 29991 R-DME-70592 https://reactome.org/PathwayBrowser/#/R-DME-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Drosophila melanogaster 29991 R-DME-70596 https://reactome.org/PathwayBrowser/#/R-DME-70596 GOT2 dimer deaminates L-Asp IEA Drosophila melanogaster 29991 R-DME-70613 https://reactome.org/PathwayBrowser/#/R-DME-70613 GOT2 transaminates OA and L-Glu IEA Drosophila melanogaster 29991 R-DME-73573 https://reactome.org/PathwayBrowser/#/R-DME-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Drosophila melanogaster 29991 R-DME-73805 https://reactome.org/PathwayBrowser/#/R-DME-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Drosophila melanogaster 29991 R-DRE-111524 https://reactome.org/PathwayBrowser/#/R-DRE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Danio rerio 29991 R-DRE-372448 https://reactome.org/PathwayBrowser/#/R-DRE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Danio rerio 29991 R-DRE-428015 https://reactome.org/PathwayBrowser/#/R-DRE-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Danio rerio 29991 R-DRE-5691507 https://reactome.org/PathwayBrowser/#/R-DRE-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Danio rerio 29991 R-DRE-5696365 https://reactome.org/PathwayBrowser/#/R-DRE-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Danio rerio 29991 R-DRE-6784393 https://reactome.org/PathwayBrowser/#/R-DRE-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Danio rerio 29991 R-DRE-70581 https://reactome.org/PathwayBrowser/#/R-DRE-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Danio rerio 29991 R-DRE-70592 https://reactome.org/PathwayBrowser/#/R-DRE-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Danio rerio 29991 R-DRE-70596 https://reactome.org/PathwayBrowser/#/R-DRE-70596 GOT2 dimer deaminates L-Asp IEA Danio rerio 29991 R-DRE-70613 https://reactome.org/PathwayBrowser/#/R-DRE-70613 GOT2 transaminates OA and L-Glu IEA Danio rerio 29991 R-DRE-73805 https://reactome.org/PathwayBrowser/#/R-DRE-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Danio rerio 29991 R-DRE-8954468 https://reactome.org/PathwayBrowser/#/R-DRE-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Danio rerio 29991 R-DRE-9717206 https://reactome.org/PathwayBrowser/#/R-DRE-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Danio rerio 29991 R-GGA-111524 https://reactome.org/PathwayBrowser/#/R-GGA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Gallus gallus 29991 R-GGA-1678854 https://reactome.org/PathwayBrowser/#/R-GGA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Gallus gallus 29991 R-GGA-187586 https://reactome.org/PathwayBrowser/#/R-GGA-187586 ATP + aspartate + citrulline <=> argininosuccinate + AMP + pyrophosphate TAS Gallus gallus 29991 R-GGA-372448 https://reactome.org/PathwayBrowser/#/R-GGA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Gallus gallus 29991 R-GGA-372559 https://reactome.org/PathwayBrowser/#/R-GGA-372559 aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate TAS Gallus gallus 29991 R-GGA-372564 https://reactome.org/PathwayBrowser/#/R-GGA-372564 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) TAS Gallus gallus 29991 R-GGA-372717 https://reactome.org/PathwayBrowser/#/R-GGA-372717 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) TAS Gallus gallus 29991 R-GGA-372719 https://reactome.org/PathwayBrowser/#/R-GGA-372719 aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate TAS Gallus gallus 29991 R-GGA-372726 https://reactome.org/PathwayBrowser/#/R-GGA-372726 aspartate [mitochondrial matrix] + glutamate [cytosol] <=> aspartate [cytosol] + glutamate [mitochondrial matrix] IEA Gallus gallus 29991 R-GGA-419223 https://reactome.org/PathwayBrowser/#/R-GGA-419223 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 29991 R-GGA-419451 https://reactome.org/PathwayBrowser/#/R-GGA-419451 carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate IEA Gallus gallus 29991 R-GGA-421201 https://reactome.org/PathwayBrowser/#/R-GGA-421201 inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate IEA Gallus gallus 29991 R-GGA-428015 https://reactome.org/PathwayBrowser/#/R-GGA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Gallus gallus 29991 R-GGA-5691507 https://reactome.org/PathwayBrowser/#/R-GGA-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Gallus gallus 29991 R-GGA-5696365 https://reactome.org/PathwayBrowser/#/R-GGA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Gallus gallus 29991 R-GGA-6784393 https://reactome.org/PathwayBrowser/#/R-GGA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Gallus gallus 29991 R-GGA-6787757 https://reactome.org/PathwayBrowser/#/R-GGA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Gallus gallus 29991 R-GGA-6797627 https://reactome.org/PathwayBrowser/#/R-GGA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Gallus gallus 29991 R-GGA-70577 https://reactome.org/PathwayBrowser/#/R-GGA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Gallus gallus 29991 R-GGA-70581 https://reactome.org/PathwayBrowser/#/R-GGA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Gallus gallus 29991 R-GGA-70592 https://reactome.org/PathwayBrowser/#/R-GGA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Gallus gallus 29991 R-GGA-70596 https://reactome.org/PathwayBrowser/#/R-GGA-70596 GOT2 dimer deaminates L-Asp IEA Gallus gallus 29991 R-GGA-70599 https://reactome.org/PathwayBrowser/#/R-GGA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Gallus gallus 29991 R-GGA-70613 https://reactome.org/PathwayBrowser/#/R-GGA-70613 GOT2 transaminates OA and L-Glu IEA Gallus gallus 29991 R-GGA-73805 https://reactome.org/PathwayBrowser/#/R-GGA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Gallus gallus 29991 R-GGA-8954468 https://reactome.org/PathwayBrowser/#/R-GGA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Gallus gallus 29991 R-HSA-111524 https://reactome.org/PathwayBrowser/#/R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] TAS Homo sapiens 29991 R-HSA-1678854 https://reactome.org/PathwayBrowser/#/R-HSA-1678854 GUSB tetramer hydrolyses CS/HS precursor TAS Homo sapiens 29991 R-HSA-372448 https://reactome.org/PathwayBrowser/#/R-HSA-372448 SLC25A12,13 exchange L-Glu and L-Asp TAS Homo sapiens 29991 R-HSA-379867 https://reactome.org/PathwayBrowser/#/R-HSA-379867 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 29991 R-HSA-380229 https://reactome.org/PathwayBrowser/#/R-HSA-380229 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 29991 R-HSA-428015 https://reactome.org/PathwayBrowser/#/R-HSA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29991 R-HSA-5625015 https://reactome.org/PathwayBrowser/#/R-HSA-5625015 Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29991 R-HSA-5625029 https://reactome.org/PathwayBrowser/#/R-HSA-5625029 SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 29991 R-HSA-5685345 https://reactome.org/PathwayBrowser/#/R-HSA-5685345 Formation of isoAsp TAS Homo sapiens 29991 R-HSA-5687520 https://reactome.org/PathwayBrowser/#/R-HSA-5687520 MetAsp transforms to L-Asp,isoAsp TAS Homo sapiens 29991 R-HSA-5691507 https://reactome.org/PathwayBrowser/#/R-HSA-5691507 ASPA deacetylates NAA to acetate and L-aspartate TAS Homo sapiens 29991 R-HSA-5696365 https://reactome.org/PathwayBrowser/#/R-HSA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe TAS Homo sapiens 29991 R-HSA-6784393 https://reactome.org/PathwayBrowser/#/R-HSA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) TAS Homo sapiens 29991 R-HSA-6787757 https://reactome.org/PathwayBrowser/#/R-HSA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs TAS Homo sapiens 29991 R-HSA-6797627 https://reactome.org/PathwayBrowser/#/R-HSA-6797627 ASPG hydrolyses L-Asn to L-Asp TAS Homo sapiens 29991 R-HSA-70577 https://reactome.org/PathwayBrowser/#/R-HSA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA TAS Homo sapiens 29991 R-HSA-70581 https://reactome.org/PathwayBrowser/#/R-HSA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] TAS Homo sapiens 29991 R-HSA-70592 https://reactome.org/PathwayBrowser/#/R-HSA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp TAS Homo sapiens 29991 R-HSA-70596 https://reactome.org/PathwayBrowser/#/R-HSA-70596 GOT2 dimer deaminates L-Asp TAS Homo sapiens 29991 R-HSA-70599 https://reactome.org/PathwayBrowser/#/R-HSA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] TAS Homo sapiens 29991 R-HSA-70613 https://reactome.org/PathwayBrowser/#/R-HSA-70613 GOT2 transaminates OA and L-Glu TAS Homo sapiens 29991 R-HSA-73573 https://reactome.org/PathwayBrowser/#/R-HSA-73573 CAD hexamer transforms CAP to N-carb-L-Asp TAS Homo sapiens 29991 R-HSA-73805 https://reactome.org/PathwayBrowser/#/R-HSA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi TAS Homo sapiens 29991 R-HSA-8954468 https://reactome.org/PathwayBrowser/#/R-HSA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA TAS Homo sapiens 29991 R-HSA-9717182 https://reactome.org/PathwayBrowser/#/R-HSA-9717182 L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP and GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 29991 R-HSA-9717202 https://reactome.org/PathwayBrowser/#/R-HSA-9717202 GNAT3 exchanges GDP for GTP in L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 29991 R-HSA-9717206 https://reactome.org/PathwayBrowser/#/R-HSA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) TAS Homo sapiens 29991 R-MMU-111519 https://reactome.org/PathwayBrowser/#/R-MMU-111519 inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate TAS Mus musculus 29991 R-MMU-111524 https://reactome.org/PathwayBrowser/#/R-MMU-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Mus musculus 29991 R-MMU-1678854 https://reactome.org/PathwayBrowser/#/R-MMU-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Mus musculus 29991 R-MMU-372448 https://reactome.org/PathwayBrowser/#/R-MMU-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Mus musculus 29991 R-MMU-428015 https://reactome.org/PathwayBrowser/#/R-MMU-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Mus musculus 29991 R-MMU-5691507 https://reactome.org/PathwayBrowser/#/R-MMU-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Mus musculus 29991 R-MMU-5696365 https://reactome.org/PathwayBrowser/#/R-MMU-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Mus musculus 29991 R-MMU-6784393 https://reactome.org/PathwayBrowser/#/R-MMU-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Mus musculus 29991 R-MMU-6787757 https://reactome.org/PathwayBrowser/#/R-MMU-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Mus musculus 29991 R-MMU-6797627 https://reactome.org/PathwayBrowser/#/R-MMU-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Mus musculus 29991 R-MMU-70577 https://reactome.org/PathwayBrowser/#/R-MMU-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Mus musculus 29991 R-MMU-70581 https://reactome.org/PathwayBrowser/#/R-MMU-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Mus musculus 29991 R-MMU-70592 https://reactome.org/PathwayBrowser/#/R-MMU-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Mus musculus 29991 R-MMU-70596 https://reactome.org/PathwayBrowser/#/R-MMU-70596 GOT2 dimer deaminates L-Asp IEA Mus musculus 29991 R-MMU-70599 https://reactome.org/PathwayBrowser/#/R-MMU-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Mus musculus 29991 R-MMU-70613 https://reactome.org/PathwayBrowser/#/R-MMU-70613 GOT2 transaminates OA and L-Glu IEA Mus musculus 29991 R-MMU-73573 https://reactome.org/PathwayBrowser/#/R-MMU-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Mus musculus 29991 R-MMU-73805 https://reactome.org/PathwayBrowser/#/R-MMU-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Mus musculus 29991 R-MMU-8954468 https://reactome.org/PathwayBrowser/#/R-MMU-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Mus musculus 29991 R-MMU-9717206 https://reactome.org/PathwayBrowser/#/R-MMU-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Mus musculus 29991 R-PFA-111524 https://reactome.org/PathwayBrowser/#/R-PFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Plasmodium falciparum 29991 R-PFA-70581 https://reactome.org/PathwayBrowser/#/R-PFA-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Plasmodium falciparum 29991 R-PFA-70592 https://reactome.org/PathwayBrowser/#/R-PFA-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Plasmodium falciparum 29991 R-PFA-70599 https://reactome.org/PathwayBrowser/#/R-PFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Plasmodium falciparum 29991 R-PFA-73573 https://reactome.org/PathwayBrowser/#/R-PFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Plasmodium falciparum 29991 R-PFA-8954468 https://reactome.org/PathwayBrowser/#/R-PFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Plasmodium falciparum 29991 R-RNO-111524 https://reactome.org/PathwayBrowser/#/R-RNO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Rattus norvegicus 29991 R-RNO-1678854 https://reactome.org/PathwayBrowser/#/R-RNO-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Rattus norvegicus 29991 R-RNO-372448 https://reactome.org/PathwayBrowser/#/R-RNO-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Rattus norvegicus 29991 R-RNO-428015 https://reactome.org/PathwayBrowser/#/R-RNO-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Rattus norvegicus 29991 R-RNO-5691507 https://reactome.org/PathwayBrowser/#/R-RNO-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Rattus norvegicus 29991 R-RNO-5696365 https://reactome.org/PathwayBrowser/#/R-RNO-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Rattus norvegicus 29991 R-RNO-6784393 https://reactome.org/PathwayBrowser/#/R-RNO-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Rattus norvegicus 29991 R-RNO-6787757 https://reactome.org/PathwayBrowser/#/R-RNO-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Rattus norvegicus 29991 R-RNO-6797627 https://reactome.org/PathwayBrowser/#/R-RNO-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Rattus norvegicus 29991 R-RNO-70581 https://reactome.org/PathwayBrowser/#/R-RNO-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Rattus norvegicus 29991 R-RNO-70592 https://reactome.org/PathwayBrowser/#/R-RNO-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Rattus norvegicus 29991 R-RNO-70596 https://reactome.org/PathwayBrowser/#/R-RNO-70596 GOT2 dimer deaminates L-Asp IEA Rattus norvegicus 29991 R-RNO-70599 https://reactome.org/PathwayBrowser/#/R-RNO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Rattus norvegicus 29991 R-RNO-70613 https://reactome.org/PathwayBrowser/#/R-RNO-70613 GOT2 transaminates OA and L-Glu IEA Rattus norvegicus 29991 R-RNO-73573 https://reactome.org/PathwayBrowser/#/R-RNO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Rattus norvegicus 29991 R-RNO-73805 https://reactome.org/PathwayBrowser/#/R-RNO-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Rattus norvegicus 29991 R-RNO-8954468 https://reactome.org/PathwayBrowser/#/R-RNO-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Rattus norvegicus 29991 R-RNO-9717206 https://reactome.org/PathwayBrowser/#/R-RNO-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Rattus norvegicus 29991 R-SCE-111524 https://reactome.org/PathwayBrowser/#/R-SCE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Saccharomyces cerevisiae 29991 R-SCE-372448 https://reactome.org/PathwayBrowser/#/R-SCE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Saccharomyces cerevisiae 29991 R-SCE-6784393 https://reactome.org/PathwayBrowser/#/R-SCE-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Saccharomyces cerevisiae 29991 R-SCE-70581 https://reactome.org/PathwayBrowser/#/R-SCE-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Saccharomyces cerevisiae 29991 R-SCE-70592 https://reactome.org/PathwayBrowser/#/R-SCE-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Saccharomyces cerevisiae 29991 R-SCE-70596 https://reactome.org/PathwayBrowser/#/R-SCE-70596 GOT2 dimer deaminates L-Asp IEA Saccharomyces cerevisiae 29991 R-SCE-70599 https://reactome.org/PathwayBrowser/#/R-SCE-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Saccharomyces cerevisiae 29991 R-SCE-70613 https://reactome.org/PathwayBrowser/#/R-SCE-70613 GOT2 transaminates OA and L-Glu IEA Saccharomyces cerevisiae 29991 R-SCE-73573 https://reactome.org/PathwayBrowser/#/R-SCE-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Saccharomyces cerevisiae 29991 R-SPO-111524 https://reactome.org/PathwayBrowser/#/R-SPO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Schizosaccharomyces pombe 29991 R-SPO-6784393 https://reactome.org/PathwayBrowser/#/R-SPO-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Schizosaccharomyces pombe 29991 R-SPO-70581 https://reactome.org/PathwayBrowser/#/R-SPO-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Schizosaccharomyces pombe 29991 R-SPO-70592 https://reactome.org/PathwayBrowser/#/R-SPO-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Schizosaccharomyces pombe 29991 R-SPO-70596 https://reactome.org/PathwayBrowser/#/R-SPO-70596 GOT2 dimer deaminates L-Asp IEA Schizosaccharomyces pombe 29991 R-SPO-70599 https://reactome.org/PathwayBrowser/#/R-SPO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Schizosaccharomyces pombe 29991 R-SPO-70613 https://reactome.org/PathwayBrowser/#/R-SPO-70613 GOT2 transaminates OA and L-Glu IEA Schizosaccharomyces pombe 29991 R-SPO-73573 https://reactome.org/PathwayBrowser/#/R-SPO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Schizosaccharomyces pombe 29991 R-SSC-111524 https://reactome.org/PathwayBrowser/#/R-SSC-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Sus scrofa 29991 R-SSC-1678854 https://reactome.org/PathwayBrowser/#/R-SSC-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Sus scrofa 29991 R-SSC-372448 https://reactome.org/PathwayBrowser/#/R-SSC-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Sus scrofa 29991 R-SSC-428015 https://reactome.org/PathwayBrowser/#/R-SSC-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Sus scrofa 29991 R-SSC-5691507 https://reactome.org/PathwayBrowser/#/R-SSC-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Sus scrofa 29991 R-SSC-5696365 https://reactome.org/PathwayBrowser/#/R-SSC-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Sus scrofa 29991 R-SSC-6784393 https://reactome.org/PathwayBrowser/#/R-SSC-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Sus scrofa 29991 R-SSC-6787757 https://reactome.org/PathwayBrowser/#/R-SSC-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Sus scrofa 29991 R-SSC-6797627 https://reactome.org/PathwayBrowser/#/R-SSC-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Sus scrofa 29991 R-SSC-70577 https://reactome.org/PathwayBrowser/#/R-SSC-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Sus scrofa 29991 R-SSC-70581 https://reactome.org/PathwayBrowser/#/R-SSC-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Sus scrofa 29991 R-SSC-70592 https://reactome.org/PathwayBrowser/#/R-SSC-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Sus scrofa 29991 R-SSC-70596 https://reactome.org/PathwayBrowser/#/R-SSC-70596 GOT2 dimer deaminates L-Asp IEA Sus scrofa 29991 R-SSC-70599 https://reactome.org/PathwayBrowser/#/R-SSC-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Sus scrofa 29991 R-SSC-70613 https://reactome.org/PathwayBrowser/#/R-SSC-70613 GOT2 transaminates OA and L-Glu IEA Sus scrofa 29991 R-SSC-73573 https://reactome.org/PathwayBrowser/#/R-SSC-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Sus scrofa 29991 R-SSC-73805 https://reactome.org/PathwayBrowser/#/R-SSC-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Sus scrofa 29991 R-SSC-8954468 https://reactome.org/PathwayBrowser/#/R-SSC-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Sus scrofa 29991 R-SSC-9717206 https://reactome.org/PathwayBrowser/#/R-SSC-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Sus scrofa 29991 R-XTR-111524 https://reactome.org/PathwayBrowser/#/R-XTR-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Xenopus tropicalis 29991 R-XTR-1678854 https://reactome.org/PathwayBrowser/#/R-XTR-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Xenopus tropicalis 29991 R-XTR-372448 https://reactome.org/PathwayBrowser/#/R-XTR-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Xenopus tropicalis 29991 R-XTR-428015 https://reactome.org/PathwayBrowser/#/R-XTR-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Xenopus tropicalis 29991 R-XTR-5691507 https://reactome.org/PathwayBrowser/#/R-XTR-5691507 ASPA deacetylates NAA to acetate and L-aspartate IEA Xenopus tropicalis 29991 R-XTR-6784393 https://reactome.org/PathwayBrowser/#/R-XTR-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Xenopus tropicalis 29991 R-XTR-6787757 https://reactome.org/PathwayBrowser/#/R-XTR-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Xenopus tropicalis 29991 R-XTR-6797627 https://reactome.org/PathwayBrowser/#/R-XTR-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Xenopus tropicalis 29991 R-XTR-70581 https://reactome.org/PathwayBrowser/#/R-XTR-70581 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] IEA Xenopus tropicalis 29991 R-XTR-70592 https://reactome.org/PathwayBrowser/#/R-XTR-70592 PXLP-K259-GOT1 transaminates 2-OG and L-Asp IEA Xenopus tropicalis 29991 R-XTR-70596 https://reactome.org/PathwayBrowser/#/R-XTR-70596 GOT2 dimer deaminates L-Asp IEA Xenopus tropicalis 29991 R-XTR-70599 https://reactome.org/PathwayBrowser/#/R-XTR-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Xenopus tropicalis 29991 R-XTR-70613 https://reactome.org/PathwayBrowser/#/R-XTR-70613 GOT2 transaminates OA and L-Glu IEA Xenopus tropicalis 29991 R-XTR-73573 https://reactome.org/PathwayBrowser/#/R-XTR-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Xenopus tropicalis 29991 R-XTR-73805 https://reactome.org/PathwayBrowser/#/R-XTR-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Xenopus tropicalis 29991 R-XTR-8954468 https://reactome.org/PathwayBrowser/#/R-XTR-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Xenopus tropicalis 30021 R-BTA-2408551 https://reactome.org/PathwayBrowser/#/R-BTA-2408551 SeMet is converted to AdoSeMet by MAT IEA Bos taurus 30021 R-CFA-2408551 https://reactome.org/PathwayBrowser/#/R-CFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Canis familiaris 30021 R-DDI-2408551 https://reactome.org/PathwayBrowser/#/R-DDI-2408551 SeMet is converted to AdoSeMet by MAT IEA Dictyostelium discoideum 30021 R-DRE-2408551 https://reactome.org/PathwayBrowser/#/R-DRE-2408551 SeMet is converted to AdoSeMet by MAT IEA Danio rerio 30021 R-GGA-2408551 https://reactome.org/PathwayBrowser/#/R-GGA-2408551 SeMet is converted to AdoSeMet by MAT IEA Gallus gallus 30021 R-HSA-2408537 https://reactome.org/PathwayBrowser/#/R-HSA-2408537 Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH IEA Homo sapiens 30021 R-HSA-2408546 https://reactome.org/PathwayBrowser/#/R-HSA-2408546 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex IEA Homo sapiens 30021 R-HSA-2408551 https://reactome.org/PathwayBrowser/#/R-HSA-2408551 SeMet is converted to AdoSeMet by MAT TAS Homo sapiens 30021 R-MMU-2408528 https://reactome.org/PathwayBrowser/#/R-MMU-2408528 Excess SeMet is cleaved into MeSeH by PXLP-K211-Cth TAS Mus musculus 30021 R-MMU-2408551 https://reactome.org/PathwayBrowser/#/R-MMU-2408551 SeMet is converted to AdoSeMet by MAT IEA Mus musculus 30021 R-PFA-2408551 https://reactome.org/PathwayBrowser/#/R-PFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Plasmodium falciparum 30021 R-RNO-2408551 https://reactome.org/PathwayBrowser/#/R-RNO-2408551 SeMet is converted to AdoSeMet by MAT IEA Rattus norvegicus 30021 R-SCE-2408551 https://reactome.org/PathwayBrowser/#/R-SCE-2408551 SeMet is converted to AdoSeMet by MAT IEA Saccharomyces cerevisiae 30021 R-SPO-2408551 https://reactome.org/PathwayBrowser/#/R-SPO-2408551 SeMet is converted to AdoSeMet by MAT IEA Schizosaccharomyces pombe 30021 R-SSC-2408551 https://reactome.org/PathwayBrowser/#/R-SSC-2408551 SeMet is converted to AdoSeMet by MAT IEA Sus scrofa 30021 R-TAE-2408513 https://reactome.org/PathwayBrowser/#/R-TAE-2408513 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Triticum aestivum 30021 R-VRA-2408510 https://reactome.org/PathwayBrowser/#/R-VRA-2408510 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Vigna radiata var. radiata 30021 R-XTR-2408551 https://reactome.org/PathwayBrowser/#/R-XTR-2408551 SeMet is converted to AdoSeMet by MAT IEA Xenopus tropicalis 30031 R-BTA-1234164 https://reactome.org/PathwayBrowser/#/R-BTA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Bos taurus 30031 R-BTA-1234165 https://reactome.org/PathwayBrowser/#/R-BTA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Bos taurus 30031 R-BTA-1234173 https://reactome.org/PathwayBrowser/#/R-BTA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Bos taurus 30031 R-BTA-1234177 https://reactome.org/PathwayBrowser/#/R-BTA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Bos taurus 30031 R-BTA-1234181 https://reactome.org/PathwayBrowser/#/R-BTA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Bos taurus 30031 R-BTA-1650808 https://reactome.org/PathwayBrowser/#/R-BTA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Bos taurus 30031 R-BTA-1980233 https://reactome.org/PathwayBrowser/#/R-BTA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Bos taurus 30031 R-BTA-1981104 https://reactome.org/PathwayBrowser/#/R-BTA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Bos taurus 30031 R-BTA-2172678 https://reactome.org/PathwayBrowser/#/R-BTA-2172678 PHF8 demethylates histone H4K20me1 IEA Bos taurus 30031 R-BTA-3222593 https://reactome.org/PathwayBrowser/#/R-BTA-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Bos taurus 30031 R-BTA-3296244 https://reactome.org/PathwayBrowser/#/R-BTA-3296244 SUCNR1 binds SUCCA IEA Bos taurus 30031 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 30031 R-BTA-389639 https://reactome.org/PathwayBrowser/#/R-BTA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Bos taurus 30031 R-BTA-433101 https://reactome.org/PathwayBrowser/#/R-BTA-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Bos taurus 30031 R-BTA-433131 https://reactome.org/PathwayBrowser/#/R-BTA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Bos taurus 30031 R-BTA-4722133 https://reactome.org/PathwayBrowser/#/R-BTA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Bos taurus 30031 R-BTA-4724279 https://reactome.org/PathwayBrowser/#/R-BTA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Bos taurus 30031 R-BTA-4724284 https://reactome.org/PathwayBrowser/#/R-BTA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Bos taurus 30031 R-BTA-4754176 https://reactome.org/PathwayBrowser/#/R-BTA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Bos taurus 30031 R-BTA-4754181 https://reactome.org/PathwayBrowser/#/R-BTA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Bos taurus 30031 R-BTA-4754187 https://reactome.org/PathwayBrowser/#/R-BTA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Bos taurus 30031 R-BTA-5423117 https://reactome.org/PathwayBrowser/#/R-BTA-5423117 PHF8 demethylates MeK21-histone H4 IEA Bos taurus 30031 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 30031 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 30031 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 30031 R-BTA-5661114 https://reactome.org/PathwayBrowser/#/R-BTA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Bos taurus 30031 R-BTA-5661115 https://reactome.org/PathwayBrowser/#/R-BTA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Bos taurus 30031 R-BTA-5661116 https://reactome.org/PathwayBrowser/#/R-BTA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Bos taurus 30031 R-BTA-5661120 https://reactome.org/PathwayBrowser/#/R-BTA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Bos taurus 30031 R-BTA-5661121 https://reactome.org/PathwayBrowser/#/R-BTA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Bos taurus 30031 R-BTA-5661122 https://reactome.org/PathwayBrowser/#/R-BTA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Bos taurus 30031 R-BTA-5661124 https://reactome.org/PathwayBrowser/#/R-BTA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Bos taurus 30031 R-BTA-5661125 https://reactome.org/PathwayBrowser/#/R-BTA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Bos taurus 30031 R-BTA-70994 https://reactome.org/PathwayBrowser/#/R-BTA-70994 SDH complex dehydrogenates succinate IEA Bos taurus 30031 R-BTA-70997 https://reactome.org/PathwayBrowser/#/R-BTA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Bos taurus 30031 R-BTA-71241 https://reactome.org/PathwayBrowser/#/R-BTA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Bos taurus 30031 R-BTA-71261 https://reactome.org/PathwayBrowser/#/R-BTA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Bos taurus 30031 R-BTA-71775 https://reactome.org/PathwayBrowser/#/R-BTA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Bos taurus 30031 R-BTA-74177 https://reactome.org/PathwayBrowser/#/R-BTA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Bos taurus 30031 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 30031 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 30031 R-BTA-8857692 https://reactome.org/PathwayBrowser/#/R-BTA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Bos taurus 30031 R-BTA-888548 https://reactome.org/PathwayBrowser/#/R-BTA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Bos taurus 30031 R-BTA-9629578 https://reactome.org/PathwayBrowser/#/R-BTA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Bos taurus 30031 R-BTA-9629591 https://reactome.org/PathwayBrowser/#/R-BTA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Bos taurus 30031 R-BTA-9629869 https://reactome.org/PathwayBrowser/#/R-BTA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Bos taurus 30031 R-BTA-9629888 https://reactome.org/PathwayBrowser/#/R-BTA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Bos taurus 30031 R-BTA-9629946 https://reactome.org/PathwayBrowser/#/R-BTA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Bos taurus 30031 R-BTA-9630022 https://reactome.org/PathwayBrowser/#/R-BTA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Bos taurus 30031 R-BTA-9630769 https://reactome.org/PathwayBrowser/#/R-BTA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Bos taurus 30031 R-BTA-9630967 https://reactome.org/PathwayBrowser/#/R-BTA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Bos taurus 30031 R-BTA-9630993 https://reactome.org/PathwayBrowser/#/R-BTA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Bos taurus 30031 R-BTA-9631356 https://reactome.org/PathwayBrowser/#/R-BTA-9631356 ASPH:Fe2+ hydroxylates an aspartate residue of F9 TAS Bos taurus 30031 R-CEL-1234165 https://reactome.org/PathwayBrowser/#/R-CEL-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 30031 R-CEL-1234173 https://reactome.org/PathwayBrowser/#/R-CEL-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 30031 R-CEL-1234177 https://reactome.org/PathwayBrowser/#/R-CEL-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 30031 R-CEL-1234181 https://reactome.org/PathwayBrowser/#/R-CEL-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 30031 R-CEL-1650808 https://reactome.org/PathwayBrowser/#/R-CEL-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Caenorhabditis elegans 30031 R-CEL-1981104 https://reactome.org/PathwayBrowser/#/R-CEL-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Caenorhabditis elegans 30031 R-CEL-2172678 https://reactome.org/PathwayBrowser/#/R-CEL-2172678 PHF8 demethylates histone H4K20me1 IEA Caenorhabditis elegans 30031 R-CEL-3222593 https://reactome.org/PathwayBrowser/#/R-CEL-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Caenorhabditis elegans 30031 R-CEL-389639 https://reactome.org/PathwayBrowser/#/R-CEL-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Caenorhabditis elegans 30031 R-CEL-433101 https://reactome.org/PathwayBrowser/#/R-CEL-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Caenorhabditis elegans 30031 R-CEL-433131 https://reactome.org/PathwayBrowser/#/R-CEL-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Caenorhabditis elegans 30031 R-CEL-4722133 https://reactome.org/PathwayBrowser/#/R-CEL-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-4724279 https://reactome.org/PathwayBrowser/#/R-CEL-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-4724284 https://reactome.org/PathwayBrowser/#/R-CEL-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-4754176 https://reactome.org/PathwayBrowser/#/R-CEL-4754176 JMJD6 demethylates MeR3-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-4754181 https://reactome.org/PathwayBrowser/#/R-CEL-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-4754187 https://reactome.org/PathwayBrowser/#/R-CEL-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-5423117 https://reactome.org/PathwayBrowser/#/R-CEL-5423117 PHF8 demethylates MeK21-histone H4 IEA Caenorhabditis elegans 30031 R-CEL-5661114 https://reactome.org/PathwayBrowser/#/R-CEL-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-5661115 https://reactome.org/PathwayBrowser/#/R-CEL-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-5661116 https://reactome.org/PathwayBrowser/#/R-CEL-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-5661120 https://reactome.org/PathwayBrowser/#/R-CEL-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-5661121 https://reactome.org/PathwayBrowser/#/R-CEL-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-5661122 https://reactome.org/PathwayBrowser/#/R-CEL-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Caenorhabditis elegans 30031 R-CEL-5661124 https://reactome.org/PathwayBrowser/#/R-CEL-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Caenorhabditis elegans 30031 R-CEL-5661125 https://reactome.org/PathwayBrowser/#/R-CEL-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Caenorhabditis elegans 30031 R-CEL-70994 https://reactome.org/PathwayBrowser/#/R-CEL-70994 SDH complex dehydrogenates succinate IEA Caenorhabditis elegans 30031 R-CEL-70997 https://reactome.org/PathwayBrowser/#/R-CEL-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Caenorhabditis elegans 30031 R-CEL-71241 https://reactome.org/PathwayBrowser/#/R-CEL-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Caenorhabditis elegans 30031 R-CEL-71261 https://reactome.org/PathwayBrowser/#/R-CEL-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Caenorhabditis elegans 30031 R-CEL-71775 https://reactome.org/PathwayBrowser/#/R-CEL-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Caenorhabditis elegans 30031 R-CEL-74177 https://reactome.org/PathwayBrowser/#/R-CEL-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Caenorhabditis elegans 30031 R-CEL-888548 https://reactome.org/PathwayBrowser/#/R-CEL-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Caenorhabditis elegans 30031 R-CEL-9629869 https://reactome.org/PathwayBrowser/#/R-CEL-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Caenorhabditis elegans 30031 R-CEL-9629888 https://reactome.org/PathwayBrowser/#/R-CEL-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Caenorhabditis elegans 30031 R-CEL-9629946 https://reactome.org/PathwayBrowser/#/R-CEL-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Caenorhabditis elegans 30031 R-CEL-9630022 https://reactome.org/PathwayBrowser/#/R-CEL-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Caenorhabditis elegans 30031 R-CEL-9630769 https://reactome.org/PathwayBrowser/#/R-CEL-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Caenorhabditis elegans 30031 R-CEL-9630993 https://reactome.org/PathwayBrowser/#/R-CEL-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Caenorhabditis elegans 30031 R-CFA-1234164 https://reactome.org/PathwayBrowser/#/R-CFA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Canis familiaris 30031 R-CFA-1234165 https://reactome.org/PathwayBrowser/#/R-CFA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 30031 R-CFA-1234173 https://reactome.org/PathwayBrowser/#/R-CFA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 30031 R-CFA-1234177 https://reactome.org/PathwayBrowser/#/R-CFA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 30031 R-CFA-1234181 https://reactome.org/PathwayBrowser/#/R-CFA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 30031 R-CFA-1650808 https://reactome.org/PathwayBrowser/#/R-CFA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Canis familiaris 30031 R-CFA-1980233 https://reactome.org/PathwayBrowser/#/R-CFA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Canis familiaris 30031 R-CFA-1981104 https://reactome.org/PathwayBrowser/#/R-CFA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Canis familiaris 30031 R-CFA-2172678 https://reactome.org/PathwayBrowser/#/R-CFA-2172678 PHF8 demethylates histone H4K20me1 IEA Canis familiaris 30031 R-CFA-3222593 https://reactome.org/PathwayBrowser/#/R-CFA-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Canis familiaris 30031 R-CFA-3296244 https://reactome.org/PathwayBrowser/#/R-CFA-3296244 SUCNR1 binds SUCCA IEA Canis familiaris 30031 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 30031 R-CFA-389639 https://reactome.org/PathwayBrowser/#/R-CFA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Canis familiaris 30031 R-CFA-433101 https://reactome.org/PathwayBrowser/#/R-CFA-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Canis familiaris 30031 R-CFA-433131 https://reactome.org/PathwayBrowser/#/R-CFA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Canis familiaris 30031 R-CFA-4722133 https://reactome.org/PathwayBrowser/#/R-CFA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Canis familiaris 30031 R-CFA-4724279 https://reactome.org/PathwayBrowser/#/R-CFA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Canis familiaris 30031 R-CFA-4724284 https://reactome.org/PathwayBrowser/#/R-CFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Canis familiaris 30031 R-CFA-4754176 https://reactome.org/PathwayBrowser/#/R-CFA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Canis familiaris 30031 R-CFA-4754181 https://reactome.org/PathwayBrowser/#/R-CFA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Canis familiaris 30031 R-CFA-4754187 https://reactome.org/PathwayBrowser/#/R-CFA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Canis familiaris 30031 R-CFA-5423117 https://reactome.org/PathwayBrowser/#/R-CFA-5423117 PHF8 demethylates MeK21-histone H4 IEA Canis familiaris 30031 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 30031 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 30031 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 30031 R-CFA-5661114 https://reactome.org/PathwayBrowser/#/R-CFA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Canis familiaris 30031 R-CFA-5661115 https://reactome.org/PathwayBrowser/#/R-CFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Canis familiaris 30031 R-CFA-5661116 https://reactome.org/PathwayBrowser/#/R-CFA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Canis familiaris 30031 R-CFA-5661120 https://reactome.org/PathwayBrowser/#/R-CFA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Canis familiaris 30031 R-CFA-5661121 https://reactome.org/PathwayBrowser/#/R-CFA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Canis familiaris 30031 R-CFA-5661122 https://reactome.org/PathwayBrowser/#/R-CFA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Canis familiaris 30031 R-CFA-5661124 https://reactome.org/PathwayBrowser/#/R-CFA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Canis familiaris 30031 R-CFA-5661125 https://reactome.org/PathwayBrowser/#/R-CFA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Canis familiaris 30031 R-CFA-70994 https://reactome.org/PathwayBrowser/#/R-CFA-70994 SDH complex dehydrogenates succinate IEA Canis familiaris 30031 R-CFA-70997 https://reactome.org/PathwayBrowser/#/R-CFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Canis familiaris 30031 R-CFA-71241 https://reactome.org/PathwayBrowser/#/R-CFA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Canis familiaris 30031 R-CFA-71261 https://reactome.org/PathwayBrowser/#/R-CFA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Canis familiaris 30031 R-CFA-71775 https://reactome.org/PathwayBrowser/#/R-CFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Canis familiaris 30031 R-CFA-74177 https://reactome.org/PathwayBrowser/#/R-CFA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Canis familiaris 30031 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 30031 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 30031 R-CFA-8857692 https://reactome.org/PathwayBrowser/#/R-CFA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Canis familiaris 30031 R-CFA-888548 https://reactome.org/PathwayBrowser/#/R-CFA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Canis familiaris 30031 R-CFA-9629578 https://reactome.org/PathwayBrowser/#/R-CFA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Canis familiaris 30031 R-CFA-9629591 https://reactome.org/PathwayBrowser/#/R-CFA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Canis familiaris 30031 R-CFA-9629869 https://reactome.org/PathwayBrowser/#/R-CFA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Canis familiaris 30031 R-CFA-9629888 https://reactome.org/PathwayBrowser/#/R-CFA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Canis familiaris 30031 R-CFA-9629946 https://reactome.org/PathwayBrowser/#/R-CFA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Canis familiaris 30031 R-CFA-9630022 https://reactome.org/PathwayBrowser/#/R-CFA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Canis familiaris 30031 R-CFA-9630769 https://reactome.org/PathwayBrowser/#/R-CFA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Canis familiaris 30031 R-CFA-9630967 https://reactome.org/PathwayBrowser/#/R-CFA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Canis familiaris 30031 R-CFA-9630993 https://reactome.org/PathwayBrowser/#/R-CFA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Canis familiaris 30031 R-DDI-2172678 https://reactome.org/PathwayBrowser/#/R-DDI-2172678 PHF8 demethylates histone H4K20me1 IEA Dictyostelium discoideum 30031 R-DDI-3222593 https://reactome.org/PathwayBrowser/#/R-DDI-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Dictyostelium discoideum 30031 R-DDI-389639 https://reactome.org/PathwayBrowser/#/R-DDI-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Dictyostelium discoideum 30031 R-DDI-4754181 https://reactome.org/PathwayBrowser/#/R-DDI-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Dictyostelium discoideum 30031 R-DDI-4754187 https://reactome.org/PathwayBrowser/#/R-DDI-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Dictyostelium discoideum 30031 R-DDI-5661116 https://reactome.org/PathwayBrowser/#/R-DDI-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Dictyostelium discoideum 30031 R-DDI-5661121 https://reactome.org/PathwayBrowser/#/R-DDI-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Dictyostelium discoideum 30031 R-DDI-70994 https://reactome.org/PathwayBrowser/#/R-DDI-70994 SDH complex dehydrogenates succinate IEA Dictyostelium discoideum 30031 R-DDI-70997 https://reactome.org/PathwayBrowser/#/R-DDI-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Dictyostelium discoideum 30031 R-DDI-71775 https://reactome.org/PathwayBrowser/#/R-DDI-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Dictyostelium discoideum 30031 R-DDI-74177 https://reactome.org/PathwayBrowser/#/R-DDI-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Dictyostelium discoideum 30031 R-DDI-9629578 https://reactome.org/PathwayBrowser/#/R-DDI-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Dictyostelium discoideum 30031 R-DDI-9629591 https://reactome.org/PathwayBrowser/#/R-DDI-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Dictyostelium discoideum 30031 R-DDI-9629869 https://reactome.org/PathwayBrowser/#/R-DDI-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Dictyostelium discoideum 30031 R-DDI-9630993 https://reactome.org/PathwayBrowser/#/R-DDI-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Dictyostelium discoideum 30031 R-DME-1234165 https://reactome.org/PathwayBrowser/#/R-DME-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 30031 R-DME-1234173 https://reactome.org/PathwayBrowser/#/R-DME-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 30031 R-DME-1234177 https://reactome.org/PathwayBrowser/#/R-DME-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 30031 R-DME-1234181 https://reactome.org/PathwayBrowser/#/R-DME-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 30031 R-DME-1981104 https://reactome.org/PathwayBrowser/#/R-DME-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Drosophila melanogaster 30031 R-DME-2172678 https://reactome.org/PathwayBrowser/#/R-DME-2172678 PHF8 demethylates histone H4K20me1 IEA Drosophila melanogaster 30031 R-DME-3222593 https://reactome.org/PathwayBrowser/#/R-DME-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Drosophila melanogaster 30031 R-DME-433101 https://reactome.org/PathwayBrowser/#/R-DME-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Drosophila melanogaster 30031 R-DME-433131 https://reactome.org/PathwayBrowser/#/R-DME-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Drosophila melanogaster 30031 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 30031 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 30031 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 30031 R-DME-5661124 https://reactome.org/PathwayBrowser/#/R-DME-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Drosophila melanogaster 30031 R-DME-5661125 https://reactome.org/PathwayBrowser/#/R-DME-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Drosophila melanogaster 30031 R-DME-70994 https://reactome.org/PathwayBrowser/#/R-DME-70994 SDH complex dehydrogenates succinate IEA Drosophila melanogaster 30031 R-DME-70997 https://reactome.org/PathwayBrowser/#/R-DME-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Drosophila melanogaster 30031 R-DME-71241 https://reactome.org/PathwayBrowser/#/R-DME-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Drosophila melanogaster 30031 R-DME-71261 https://reactome.org/PathwayBrowser/#/R-DME-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Drosophila melanogaster 30031 R-DME-71775 https://reactome.org/PathwayBrowser/#/R-DME-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Drosophila melanogaster 30031 R-DME-74177 https://reactome.org/PathwayBrowser/#/R-DME-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Drosophila melanogaster 30031 R-DME-888548 https://reactome.org/PathwayBrowser/#/R-DME-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Drosophila melanogaster 30031 R-DME-9629578 https://reactome.org/PathwayBrowser/#/R-DME-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Drosophila melanogaster 30031 R-DME-9629591 https://reactome.org/PathwayBrowser/#/R-DME-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Drosophila melanogaster 30031 R-DME-9629869 https://reactome.org/PathwayBrowser/#/R-DME-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Drosophila melanogaster 30031 R-DME-9629888 https://reactome.org/PathwayBrowser/#/R-DME-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Drosophila melanogaster 30031 R-DME-9629946 https://reactome.org/PathwayBrowser/#/R-DME-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Drosophila melanogaster 30031 R-DME-9630022 https://reactome.org/PathwayBrowser/#/R-DME-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Drosophila melanogaster 30031 R-DME-9630769 https://reactome.org/PathwayBrowser/#/R-DME-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Drosophila melanogaster 30031 R-DME-9630993 https://reactome.org/PathwayBrowser/#/R-DME-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Drosophila melanogaster 30031 R-DRE-1234164 https://reactome.org/PathwayBrowser/#/R-DRE-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Danio rerio 30031 R-DRE-1234165 https://reactome.org/PathwayBrowser/#/R-DRE-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Danio rerio 30031 R-DRE-1234181 https://reactome.org/PathwayBrowser/#/R-DRE-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Danio rerio 30031 R-DRE-1650808 https://reactome.org/PathwayBrowser/#/R-DRE-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Danio rerio 30031 R-DRE-1981104 https://reactome.org/PathwayBrowser/#/R-DRE-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Danio rerio 30031 R-DRE-2172678 https://reactome.org/PathwayBrowser/#/R-DRE-2172678 PHF8 demethylates histone H4K20me1 IEA Danio rerio 30031 R-DRE-389639 https://reactome.org/PathwayBrowser/#/R-DRE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Danio rerio 30031 R-DRE-433101 https://reactome.org/PathwayBrowser/#/R-DRE-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Danio rerio 30031 R-DRE-433131 https://reactome.org/PathwayBrowser/#/R-DRE-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Danio rerio 30031 R-DRE-5423117 https://reactome.org/PathwayBrowser/#/R-DRE-5423117 PHF8 demethylates MeK21-histone H4 IEA Danio rerio 30031 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 30031 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 30031 R-DRE-5661124 https://reactome.org/PathwayBrowser/#/R-DRE-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Danio rerio 30031 R-DRE-5661125 https://reactome.org/PathwayBrowser/#/R-DRE-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Danio rerio 30031 R-DRE-70994 https://reactome.org/PathwayBrowser/#/R-DRE-70994 SDH complex dehydrogenates succinate IEA Danio rerio 30031 R-DRE-70997 https://reactome.org/PathwayBrowser/#/R-DRE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Danio rerio 30031 R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio 30031 R-DRE-74177 https://reactome.org/PathwayBrowser/#/R-DRE-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Danio rerio 30031 R-DRE-8857692 https://reactome.org/PathwayBrowser/#/R-DRE-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Danio rerio 30031 R-DRE-9629591 https://reactome.org/PathwayBrowser/#/R-DRE-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Danio rerio 30031 R-DRE-9629869 https://reactome.org/PathwayBrowser/#/R-DRE-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Danio rerio 30031 R-DRE-9629946 https://reactome.org/PathwayBrowser/#/R-DRE-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Danio rerio 30031 R-DRE-9630993 https://reactome.org/PathwayBrowser/#/R-DRE-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Danio rerio 30031 R-GGA-1234164 https://reactome.org/PathwayBrowser/#/R-GGA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Gallus gallus 30031 R-GGA-1234165 https://reactome.org/PathwayBrowser/#/R-GGA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 30031 R-GGA-1234173 https://reactome.org/PathwayBrowser/#/R-GGA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 30031 R-GGA-1234177 https://reactome.org/PathwayBrowser/#/R-GGA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 30031 R-GGA-1234181 https://reactome.org/PathwayBrowser/#/R-GGA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 30031 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus 30031 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus 30031 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus 30031 R-GGA-2172678 https://reactome.org/PathwayBrowser/#/R-GGA-2172678 PHF8 demethylates histone H4K20me1 IEA Gallus gallus 30031 R-GGA-3296244 https://reactome.org/PathwayBrowser/#/R-GGA-3296244 SUCNR1 binds SUCCA IEA Gallus gallus 30031 R-GGA-353356 https://reactome.org/PathwayBrowser/#/R-GGA-353356 Reversal of Alkylation Damage By DNA Dioxygenases TAS Gallus gallus 30031 R-GGA-372977 https://reactome.org/PathwayBrowser/#/R-GGA-372977 succinylCoA + ADP + Pi <=> succinate + CoASH + ATP TAS Gallus gallus 30031 R-GGA-372980 https://reactome.org/PathwayBrowser/#/R-GGA-372980 succinylCoA + GDP + Pi <=> succinate + CoASH + GTP TAS Gallus gallus 30031 R-GGA-373129 https://reactome.org/PathwayBrowser/#/R-GGA-373129 fumarate + FADH2 <=> succinate + FAD IEA Gallus gallus 30031 R-GGA-373134 https://reactome.org/PathwayBrowser/#/R-GGA-373134 succinate + CoASH + ATP <=> succinylCoA + ADP + Pi TAS Gallus gallus 30031 R-GGA-373147 https://reactome.org/PathwayBrowser/#/R-GGA-373147 succinate + FAD <=> fumarate + FADH2 IEA Gallus gallus 30031 R-GGA-373148 https://reactome.org/PathwayBrowser/#/R-GGA-373148 succinate + CoASH + GTP <=> succinylCoA + GDP + Pi TAS Gallus gallus 30031 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 30031 R-GGA-389639 https://reactome.org/PathwayBrowser/#/R-GGA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Gallus gallus 30031 R-GGA-433101 https://reactome.org/PathwayBrowser/#/R-GGA-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Gallus gallus 30031 R-GGA-433131 https://reactome.org/PathwayBrowser/#/R-GGA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Gallus gallus 30031 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 30031 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 30031 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 30031 R-GGA-5661124 https://reactome.org/PathwayBrowser/#/R-GGA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Gallus gallus 30031 R-GGA-5661125 https://reactome.org/PathwayBrowser/#/R-GGA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Gallus gallus 30031 R-GGA-70994 https://reactome.org/PathwayBrowser/#/R-GGA-70994 SDH complex dehydrogenates succinate IEA Gallus gallus 30031 R-GGA-70997 https://reactome.org/PathwayBrowser/#/R-GGA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Gallus gallus 30031 R-GGA-71241 https://reactome.org/PathwayBrowser/#/R-GGA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Gallus gallus 30031 R-GGA-71261 https://reactome.org/PathwayBrowser/#/R-GGA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Gallus gallus 30031 R-GGA-71775 https://reactome.org/PathwayBrowser/#/R-GGA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Gallus gallus 30031 R-GGA-74177 https://reactome.org/PathwayBrowser/#/R-GGA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Gallus gallus 30031 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 30031 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 30031 R-GGA-8857692 https://reactome.org/PathwayBrowser/#/R-GGA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Gallus gallus 30031 R-GGA-888548 https://reactome.org/PathwayBrowser/#/R-GGA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Gallus gallus 30031 R-GGA-9629578 https://reactome.org/PathwayBrowser/#/R-GGA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Gallus gallus 30031 R-GGA-9629591 https://reactome.org/PathwayBrowser/#/R-GGA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Gallus gallus 30031 R-GGA-9629869 https://reactome.org/PathwayBrowser/#/R-GGA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Gallus gallus 30031 R-GGA-9629946 https://reactome.org/PathwayBrowser/#/R-GGA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Gallus gallus 30031 R-GGA-9630022 https://reactome.org/PathwayBrowser/#/R-GGA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Gallus gallus 30031 R-GGA-9630769 https://reactome.org/PathwayBrowser/#/R-GGA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Gallus gallus 30031 R-GGA-9630967 https://reactome.org/PathwayBrowser/#/R-GGA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Gallus gallus 30031 R-GGA-9630993 https://reactome.org/PathwayBrowser/#/R-GGA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Gallus gallus 30031 R-HSA-112118 https://reactome.org/PathwayBrowser/#/R-HSA-112118 Oxidative demethylation of 1-meA damaged DNA by ALKBH2 TAS Homo sapiens 30031 R-HSA-112120 https://reactome.org/PathwayBrowser/#/R-HSA-112120 Oxidative demethylation of 3-meC damaged DNA by ALKBH2 TAS Homo sapiens 30031 R-HSA-112121 https://reactome.org/PathwayBrowser/#/R-HSA-112121 Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 TAS Homo sapiens 30031 R-HSA-112123 https://reactome.org/PathwayBrowser/#/R-HSA-112123 Oxidative demethylation of 1-meA damaged DNA By ALKBH3 TAS Homo sapiens 30031 R-HSA-112124 https://reactome.org/PathwayBrowser/#/R-HSA-112124 Oxidative demethylation of 3-meC damaged DNA By ALKBH3 TAS Homo sapiens 30031 R-HSA-112125 https://reactome.org/PathwayBrowser/#/R-HSA-112125 Oxidative dealkylation of 1-EtA damaged DNA by ABH3 TAS Homo sapiens 30031 R-HSA-1234164 https://reactome.org/PathwayBrowser/#/R-HSA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) TAS Homo sapiens 30031 R-HSA-1234165 https://reactome.org/PathwayBrowser/#/R-HSA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 30031 R-HSA-1234166 https://reactome.org/PathwayBrowser/#/R-HSA-1234166 Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 30031 R-HSA-1234173 https://reactome.org/PathwayBrowser/#/R-HSA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 30031 R-HSA-1234177 https://reactome.org/PathwayBrowser/#/R-HSA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 30031 R-HSA-1234179 https://reactome.org/PathwayBrowser/#/R-HSA-1234179 Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 30031 R-HSA-1234181 https://reactome.org/PathwayBrowser/#/R-HSA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 30031 R-HSA-163213 https://reactome.org/PathwayBrowser/#/R-HSA-163213 Transfer of electrons through the succinate dehydrogenase complex IEA Homo sapiens 30031 R-HSA-1650808 https://reactome.org/PathwayBrowser/#/R-HSA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines TAS Homo sapiens 30031 R-HSA-1980233 https://reactome.org/PathwayBrowser/#/R-HSA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen TAS Homo sapiens 30031 R-HSA-1981104 https://reactome.org/PathwayBrowser/#/R-HSA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines TAS Homo sapiens 30031 R-HSA-2172678 https://reactome.org/PathwayBrowser/#/R-HSA-2172678 PHF8 demethylates histone H4K20me1 TAS Homo sapiens 30031 R-HSA-3222593 https://reactome.org/PathwayBrowser/#/R-HSA-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter TAS Homo sapiens 30031 R-HSA-3296244 https://reactome.org/PathwayBrowser/#/R-HSA-3296244 SUCNR1 binds SUCCA TAS Homo sapiens 30031 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 30031 R-HSA-389639 https://reactome.org/PathwayBrowser/#/R-HSA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 TAS Homo sapiens 30031 R-HSA-433101 https://reactome.org/PathwayBrowser/#/R-HSA-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion TAS Homo sapiens 30031 R-HSA-433131 https://reactome.org/PathwayBrowser/#/R-HSA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion TAS Homo sapiens 30031 R-HSA-4722133 https://reactome.org/PathwayBrowser/#/R-HSA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 TAS Homo sapiens 30031 R-HSA-4724279 https://reactome.org/PathwayBrowser/#/R-HSA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 TAS Homo sapiens 30031 R-HSA-4724284 https://reactome.org/PathwayBrowser/#/R-HSA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 TAS Homo sapiens 30031 R-HSA-4754176 https://reactome.org/PathwayBrowser/#/R-HSA-4754176 JMJD6 demethylates MeR3-histone H3 TAS Homo sapiens 30031 R-HSA-4754181 https://reactome.org/PathwayBrowser/#/R-HSA-4754181 KDM5A-D demethylate Me2K5-histone H3 TAS Homo sapiens 30031 R-HSA-4754187 https://reactome.org/PathwayBrowser/#/R-HSA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 TAS Homo sapiens 30031 R-HSA-5220952 https://reactome.org/PathwayBrowser/#/R-HSA-5220952 TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine IEA Homo sapiens 30031 R-HSA-5220990 https://reactome.org/PathwayBrowser/#/R-HSA-5220990 TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine IEA Homo sapiens 30031 R-HSA-5221014 https://reactome.org/PathwayBrowser/#/R-HSA-5221014 TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine IEA Homo sapiens 30031 R-HSA-5423117 https://reactome.org/PathwayBrowser/#/R-HSA-5423117 PHF8 demethylates MeK21-histone H4 TAS Homo sapiens 30031 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 30031 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 30031 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 30031 R-HSA-5661114 https://reactome.org/PathwayBrowser/#/R-HSA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 TAS Homo sapiens 30031 R-HSA-5661115 https://reactome.org/PathwayBrowser/#/R-HSA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 TAS Homo sapiens 30031 R-HSA-5661116 https://reactome.org/PathwayBrowser/#/R-HSA-5661116 KDM5A-D demethylate Me3K5-histone H3 TAS Homo sapiens 30031 R-HSA-5661120 https://reactome.org/PathwayBrowser/#/R-HSA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 TAS Homo sapiens 30031 R-HSA-5661121 https://reactome.org/PathwayBrowser/#/R-HSA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 TAS Homo sapiens 30031 R-HSA-5661122 https://reactome.org/PathwayBrowser/#/R-HSA-5661122 JMJD6 demethylates Me2R3-histone H3 TAS Homo sapiens 30031 R-HSA-5661124 https://reactome.org/PathwayBrowser/#/R-HSA-5661124 JMJD6 demethylates MeR4-HIST1H4 TAS Homo sapiens 30031 R-HSA-5661125 https://reactome.org/PathwayBrowser/#/R-HSA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 TAS Homo sapiens 30031 R-HSA-6783455 https://reactome.org/PathwayBrowser/#/R-HSA-6783455 TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 30031 R-HSA-70994 https://reactome.org/PathwayBrowser/#/R-HSA-70994 SDH complex dehydrogenates succinate TAS Homo sapiens 30031 R-HSA-70997 https://reactome.org/PathwayBrowser/#/R-HSA-70997 SUCLG1/A2 cleaves succinyl-CoA TAS Homo sapiens 30031 R-HSA-71241 https://reactome.org/PathwayBrowser/#/R-HSA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA TAS Homo sapiens 30031 R-HSA-71261 https://reactome.org/PathwayBrowser/#/R-HSA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA TAS Homo sapiens 30031 R-HSA-71775 https://reactome.org/PathwayBrowser/#/R-HSA-71775 SUCLG1/G2 cleaves succinyl-CoA TAS Homo sapiens 30031 R-HSA-74177 https://reactome.org/PathwayBrowser/#/R-HSA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA TAS Homo sapiens 30031 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 30031 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 30031 R-HSA-8857692 https://reactome.org/PathwayBrowser/#/R-HSA-8857692 RNA demethylases demethylate N6-methyladenosine RNA TAS Homo sapiens 30031 R-HSA-888548 https://reactome.org/PathwayBrowser/#/R-HSA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA TAS Homo sapiens 30031 R-HSA-9629578 https://reactome.org/PathwayBrowser/#/R-HSA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 TAS Homo sapiens 30031 R-HSA-9629591 https://reactome.org/PathwayBrowser/#/R-HSA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 TAS Homo sapiens 30031 R-HSA-9629869 https://reactome.org/PathwayBrowser/#/R-HSA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 TAS Homo sapiens 30031 R-HSA-9629888 https://reactome.org/PathwayBrowser/#/R-HSA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 TAS Homo sapiens 30031 R-HSA-9629946 https://reactome.org/PathwayBrowser/#/R-HSA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 TAS Homo sapiens 30031 R-HSA-9630022 https://reactome.org/PathwayBrowser/#/R-HSA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 TAS Homo sapiens 30031 R-HSA-9630769 https://reactome.org/PathwayBrowser/#/R-HSA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 TAS Homo sapiens 30031 R-HSA-9630967 https://reactome.org/PathwayBrowser/#/R-HSA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A TAS Homo sapiens 30031 R-HSA-9630993 https://reactome.org/PathwayBrowser/#/R-HSA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 TAS Homo sapiens 30031 R-HSA-9631355 https://reactome.org/PathwayBrowser/#/R-HSA-9631355 ASPH:Fe2+ hydroxylates an aspartate residue of F9 IEA Homo sapiens 30031 R-HSA-9817458 https://reactome.org/PathwayBrowser/#/R-HSA-9817458 TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 IEA Homo sapiens 30031 R-HSA-9822461 https://reactome.org/PathwayBrowser/#/R-HSA-9822461 KDM5B demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 30031 R-HSA-9822467 https://reactome.org/PathwayBrowser/#/R-HSA-9822467 KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 30031 R-HSA-9822914 https://reactome.org/PathwayBrowser/#/R-HSA-9822914 KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 30031 R-HSA-9822985 https://reactome.org/PathwayBrowser/#/R-HSA-9822985 KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 30031 R-MMU-1234164 https://reactome.org/PathwayBrowser/#/R-MMU-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Mus musculus 30031 R-MMU-1234165 https://reactome.org/PathwayBrowser/#/R-MMU-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Mus musculus 30031 R-MMU-1234173 https://reactome.org/PathwayBrowser/#/R-MMU-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Mus musculus 30031 R-MMU-1234177 https://reactome.org/PathwayBrowser/#/R-MMU-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Mus musculus 30031 R-MMU-1234181 https://reactome.org/PathwayBrowser/#/R-MMU-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Mus musculus 30031 R-MMU-1650808 https://reactome.org/PathwayBrowser/#/R-MMU-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Mus musculus 30031 R-MMU-1980233 https://reactome.org/PathwayBrowser/#/R-MMU-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Mus musculus 30031 R-MMU-1981104 https://reactome.org/PathwayBrowser/#/R-MMU-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Mus musculus 30031 R-MMU-3296244 https://reactome.org/PathwayBrowser/#/R-MMU-3296244 SUCNR1 binds SUCCA IEA Mus musculus 30031 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 30031 R-MMU-389639 https://reactome.org/PathwayBrowser/#/R-MMU-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Mus musculus 30031 R-MMU-433101 https://reactome.org/PathwayBrowser/#/R-MMU-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Mus musculus 30031 R-MMU-433131 https://reactome.org/PathwayBrowser/#/R-MMU-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Mus musculus 30031 R-MMU-4722133 https://reactome.org/PathwayBrowser/#/R-MMU-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Mus musculus 30031 R-MMU-4724279 https://reactome.org/PathwayBrowser/#/R-MMU-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Mus musculus 30031 R-MMU-4724284 https://reactome.org/PathwayBrowser/#/R-MMU-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Mus musculus 30031 R-MMU-4754176 https://reactome.org/PathwayBrowser/#/R-MMU-4754176 JMJD6 demethylates MeR3-histone H3 IEA Mus musculus 30031 R-MMU-4754181 https://reactome.org/PathwayBrowser/#/R-MMU-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Mus musculus 30031 R-MMU-4754187 https://reactome.org/PathwayBrowser/#/R-MMU-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Mus musculus 30031 R-MMU-5220931 https://reactome.org/PathwayBrowser/#/R-MMU-5220931 Tet1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine TAS Mus musculus 30031 R-MMU-5220936 https://reactome.org/PathwayBrowser/#/R-MMU-5220936 Tet1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine TAS Mus musculus 30031 R-MMU-5220944 https://reactome.org/PathwayBrowser/#/R-MMU-5220944 Tet1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine TAS Mus musculus 30031 R-MMU-5423117 https://reactome.org/PathwayBrowser/#/R-MMU-5423117 PHF8 demethylates MeK21-histone H4 IEA Mus musculus 30031 R-MMU-5661114 https://reactome.org/PathwayBrowser/#/R-MMU-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Mus musculus 30031 R-MMU-5661115 https://reactome.org/PathwayBrowser/#/R-MMU-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Mus musculus 30031 R-MMU-5661116 https://reactome.org/PathwayBrowser/#/R-MMU-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Mus musculus 30031 R-MMU-5661120 https://reactome.org/PathwayBrowser/#/R-MMU-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Mus musculus 30031 R-MMU-5661121 https://reactome.org/PathwayBrowser/#/R-MMU-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Mus musculus 30031 R-MMU-5661122 https://reactome.org/PathwayBrowser/#/R-MMU-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Mus musculus 30031 R-MMU-5661124 https://reactome.org/PathwayBrowser/#/R-MMU-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Mus musculus 30031 R-MMU-5661125 https://reactome.org/PathwayBrowser/#/R-MMU-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Mus musculus 30031 R-MMU-70994 https://reactome.org/PathwayBrowser/#/R-MMU-70994 SDH complex dehydrogenates succinate IEA Mus musculus 30031 R-MMU-70997 https://reactome.org/PathwayBrowser/#/R-MMU-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Mus musculus 30031 R-MMU-71241 https://reactome.org/PathwayBrowser/#/R-MMU-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Mus musculus 30031 R-MMU-71261 https://reactome.org/PathwayBrowser/#/R-MMU-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Mus musculus 30031 R-MMU-71775 https://reactome.org/PathwayBrowser/#/R-MMU-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Mus musculus 30031 R-MMU-74177 https://reactome.org/PathwayBrowser/#/R-MMU-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Mus musculus 30031 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 30031 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 30031 R-MMU-8857692 https://reactome.org/PathwayBrowser/#/R-MMU-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Mus musculus 30031 R-MMU-888548 https://reactome.org/PathwayBrowser/#/R-MMU-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Mus musculus 30031 R-MMU-9629578 https://reactome.org/PathwayBrowser/#/R-MMU-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Mus musculus 30031 R-MMU-9629591 https://reactome.org/PathwayBrowser/#/R-MMU-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Mus musculus 30031 R-MMU-9629869 https://reactome.org/PathwayBrowser/#/R-MMU-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Mus musculus 30031 R-MMU-9629888 https://reactome.org/PathwayBrowser/#/R-MMU-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Mus musculus 30031 R-MMU-9629946 https://reactome.org/PathwayBrowser/#/R-MMU-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Mus musculus 30031 R-MMU-9630022 https://reactome.org/PathwayBrowser/#/R-MMU-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Mus musculus 30031 R-MMU-9630769 https://reactome.org/PathwayBrowser/#/R-MMU-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Mus musculus 30031 R-MMU-9630967 https://reactome.org/PathwayBrowser/#/R-MMU-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Mus musculus 30031 R-MMU-9630993 https://reactome.org/PathwayBrowser/#/R-MMU-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Mus musculus 30031 R-MMU-9817463 https://reactome.org/PathwayBrowser/#/R-MMU-9817463 Tet3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 dimethylated on lysine-9 TAS Mus musculus 30031 R-MMU-9822448 https://reactome.org/PathwayBrowser/#/R-MMU-9822448 Kdm5b demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 30031 R-MMU-9822463 https://reactome.org/PathwayBrowser/#/R-MMU-9822463 Kdm5a demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 30031 R-MMU-9822924 https://reactome.org/PathwayBrowser/#/R-MMU-9822924 Kdm6b (Jmjd3) demethylates histone H3 trimethyllysine-27 (H3K27me3) TAS Mus musculus 30031 R-MMU-9822964 https://reactome.org/PathwayBrowser/#/R-MMU-9822964 Kdm6a (Utx) demethylates trimethylated histone H3 lysine-27 (H3K27me3) TAS Mus musculus 30031 R-PFA-2172678 https://reactome.org/PathwayBrowser/#/R-PFA-2172678 PHF8 demethylates histone H4K20me1 IEA Plasmodium falciparum 30031 R-PFA-4724284 https://reactome.org/PathwayBrowser/#/R-PFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Plasmodium falciparum 30031 R-PFA-5661115 https://reactome.org/PathwayBrowser/#/R-PFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Plasmodium falciparum 30031 R-PFA-70997 https://reactome.org/PathwayBrowser/#/R-PFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Plasmodium falciparum 30031 R-PFA-71775 https://reactome.org/PathwayBrowser/#/R-PFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Plasmodium falciparum 30031 R-RNO-1234164 https://reactome.org/PathwayBrowser/#/R-RNO-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Rattus norvegicus 30031 R-RNO-1234165 https://reactome.org/PathwayBrowser/#/R-RNO-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 30031 R-RNO-1234173 https://reactome.org/PathwayBrowser/#/R-RNO-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 30031 R-RNO-1234177 https://reactome.org/PathwayBrowser/#/R-RNO-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 30031 R-RNO-1234181 https://reactome.org/PathwayBrowser/#/R-RNO-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 30031 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus 30031 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus 30031 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus 30031 R-RNO-2172678 https://reactome.org/PathwayBrowser/#/R-RNO-2172678 PHF8 demethylates histone H4K20me1 IEA Rattus norvegicus 30031 R-RNO-3222593 https://reactome.org/PathwayBrowser/#/R-RNO-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Rattus norvegicus 30031 R-RNO-3296244 https://reactome.org/PathwayBrowser/#/R-RNO-3296244 SUCNR1 binds SUCCA IEA Rattus norvegicus 30031 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 30031 R-RNO-389639 https://reactome.org/PathwayBrowser/#/R-RNO-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Rattus norvegicus 30031 R-RNO-433101 https://reactome.org/PathwayBrowser/#/R-RNO-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Rattus norvegicus 30031 R-RNO-433131 https://reactome.org/PathwayBrowser/#/R-RNO-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Rattus norvegicus 30031 R-RNO-4722133 https://reactome.org/PathwayBrowser/#/R-RNO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Rattus norvegicus 30031 R-RNO-4724279 https://reactome.org/PathwayBrowser/#/R-RNO-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Rattus norvegicus 30031 R-RNO-4724284 https://reactome.org/PathwayBrowser/#/R-RNO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Rattus norvegicus 30031 R-RNO-4754176 https://reactome.org/PathwayBrowser/#/R-RNO-4754176 JMJD6 demethylates MeR3-histone H3 IEA Rattus norvegicus 30031 R-RNO-4754181 https://reactome.org/PathwayBrowser/#/R-RNO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Rattus norvegicus 30031 R-RNO-4754187 https://reactome.org/PathwayBrowser/#/R-RNO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Rattus norvegicus 30031 R-RNO-5423117 https://reactome.org/PathwayBrowser/#/R-RNO-5423117 PHF8 demethylates MeK21-histone H4 IEA Rattus norvegicus 30031 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 30031 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 30031 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 30031 R-RNO-5661114 https://reactome.org/PathwayBrowser/#/R-RNO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Rattus norvegicus 30031 R-RNO-5661115 https://reactome.org/PathwayBrowser/#/R-RNO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Rattus norvegicus 30031 R-RNO-5661116 https://reactome.org/PathwayBrowser/#/R-RNO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Rattus norvegicus 30031 R-RNO-5661120 https://reactome.org/PathwayBrowser/#/R-RNO-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Rattus norvegicus 30031 R-RNO-5661121 https://reactome.org/PathwayBrowser/#/R-RNO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Rattus norvegicus 30031 R-RNO-5661122 https://reactome.org/PathwayBrowser/#/R-RNO-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Rattus norvegicus 30031 R-RNO-5661124 https://reactome.org/PathwayBrowser/#/R-RNO-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Rattus norvegicus 30031 R-RNO-5661125 https://reactome.org/PathwayBrowser/#/R-RNO-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Rattus norvegicus 30031 R-RNO-70994 https://reactome.org/PathwayBrowser/#/R-RNO-70994 SDH complex dehydrogenates succinate IEA Rattus norvegicus 30031 R-RNO-70997 https://reactome.org/PathwayBrowser/#/R-RNO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Rattus norvegicus 30031 R-RNO-71241 https://reactome.org/PathwayBrowser/#/R-RNO-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Rattus norvegicus 30031 R-RNO-71261 https://reactome.org/PathwayBrowser/#/R-RNO-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Rattus norvegicus 30031 R-RNO-71775 https://reactome.org/PathwayBrowser/#/R-RNO-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Rattus norvegicus 30031 R-RNO-74177 https://reactome.org/PathwayBrowser/#/R-RNO-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Rattus norvegicus 30031 R-RNO-8857692 https://reactome.org/PathwayBrowser/#/R-RNO-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Rattus norvegicus 30031 R-RNO-888548 https://reactome.org/PathwayBrowser/#/R-RNO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Rattus norvegicus 30031 R-RNO-9629578 https://reactome.org/PathwayBrowser/#/R-RNO-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Rattus norvegicus 30031 R-RNO-9629591 https://reactome.org/PathwayBrowser/#/R-RNO-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Rattus norvegicus 30031 R-RNO-9629869 https://reactome.org/PathwayBrowser/#/R-RNO-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Rattus norvegicus 30031 R-RNO-9629888 https://reactome.org/PathwayBrowser/#/R-RNO-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Rattus norvegicus 30031 R-RNO-9629946 https://reactome.org/PathwayBrowser/#/R-RNO-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Rattus norvegicus 30031 R-RNO-9630022 https://reactome.org/PathwayBrowser/#/R-RNO-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Rattus norvegicus 30031 R-RNO-9630769 https://reactome.org/PathwayBrowser/#/R-RNO-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Rattus norvegicus 30031 R-RNO-9630967 https://reactome.org/PathwayBrowser/#/R-RNO-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Rattus norvegicus 30031 R-RNO-9630993 https://reactome.org/PathwayBrowser/#/R-RNO-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Rattus norvegicus 30031 R-SCE-2172678 https://reactome.org/PathwayBrowser/#/R-SCE-2172678 PHF8 demethylates histone H4K20me1 IEA Saccharomyces cerevisiae 30031 R-SCE-3222593 https://reactome.org/PathwayBrowser/#/R-SCE-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Saccharomyces cerevisiae 30031 R-SCE-389639 https://reactome.org/PathwayBrowser/#/R-SCE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Saccharomyces cerevisiae 30031 R-SCE-4722133 https://reactome.org/PathwayBrowser/#/R-SCE-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Saccharomyces cerevisiae 30031 R-SCE-4724279 https://reactome.org/PathwayBrowser/#/R-SCE-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Saccharomyces cerevisiae 30031 R-SCE-4754181 https://reactome.org/PathwayBrowser/#/R-SCE-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Saccharomyces cerevisiae 30031 R-SCE-4754187 https://reactome.org/PathwayBrowser/#/R-SCE-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Saccharomyces cerevisiae 30031 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 30031 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 30031 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 30031 R-SCE-5661114 https://reactome.org/PathwayBrowser/#/R-SCE-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Saccharomyces cerevisiae 30031 R-SCE-5661116 https://reactome.org/PathwayBrowser/#/R-SCE-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Saccharomyces cerevisiae 30031 R-SCE-5661120 https://reactome.org/PathwayBrowser/#/R-SCE-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Saccharomyces cerevisiae 30031 R-SCE-5661121 https://reactome.org/PathwayBrowser/#/R-SCE-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Saccharomyces cerevisiae 30031 R-SCE-70994 https://reactome.org/PathwayBrowser/#/R-SCE-70994 SDH complex dehydrogenates succinate IEA Saccharomyces cerevisiae 30031 R-SCE-70997 https://reactome.org/PathwayBrowser/#/R-SCE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Saccharomyces cerevisiae 30031 R-SCE-71261 https://reactome.org/PathwayBrowser/#/R-SCE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Saccharomyces cerevisiae 30031 R-SCE-888548 https://reactome.org/PathwayBrowser/#/R-SCE-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Saccharomyces cerevisiae 30031 R-SCE-9630769 https://reactome.org/PathwayBrowser/#/R-SCE-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Saccharomyces cerevisiae 30031 R-SPO-2172678 https://reactome.org/PathwayBrowser/#/R-SPO-2172678 PHF8 demethylates histone H4K20me1 IEA Schizosaccharomyces pombe 30031 R-SPO-3222593 https://reactome.org/PathwayBrowser/#/R-SPO-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Schizosaccharomyces pombe 30031 R-SPO-4722133 https://reactome.org/PathwayBrowser/#/R-SPO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Schizosaccharomyces pombe 30031 R-SPO-4724284 https://reactome.org/PathwayBrowser/#/R-SPO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Schizosaccharomyces pombe 30031 R-SPO-4754181 https://reactome.org/PathwayBrowser/#/R-SPO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Schizosaccharomyces pombe 30031 R-SPO-4754187 https://reactome.org/PathwayBrowser/#/R-SPO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Schizosaccharomyces pombe 30031 R-SPO-5423117 https://reactome.org/PathwayBrowser/#/R-SPO-5423117 PHF8 demethylates MeK21-histone H4 IEA Schizosaccharomyces pombe 30031 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 30031 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 30031 R-SPO-5661114 https://reactome.org/PathwayBrowser/#/R-SPO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Schizosaccharomyces pombe 30031 R-SPO-5661115 https://reactome.org/PathwayBrowser/#/R-SPO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Schizosaccharomyces pombe 30031 R-SPO-5661116 https://reactome.org/PathwayBrowser/#/R-SPO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Schizosaccharomyces pombe 30031 R-SPO-5661121 https://reactome.org/PathwayBrowser/#/R-SPO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Schizosaccharomyces pombe 30031 R-SPO-70994 https://reactome.org/PathwayBrowser/#/R-SPO-70994 SDH complex dehydrogenates succinate IEA Schizosaccharomyces pombe 30031 R-SPO-70997 https://reactome.org/PathwayBrowser/#/R-SPO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Schizosaccharomyces pombe 30031 R-SPO-888548 https://reactome.org/PathwayBrowser/#/R-SPO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Schizosaccharomyces pombe 30031 R-SPO-9629946 https://reactome.org/PathwayBrowser/#/R-SPO-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Schizosaccharomyces pombe 30031 R-SPO-9630769 https://reactome.org/PathwayBrowser/#/R-SPO-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Schizosaccharomyces pombe 30031 R-SSC-1234164 https://reactome.org/PathwayBrowser/#/R-SSC-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Sus scrofa 30031 R-SSC-1234165 https://reactome.org/PathwayBrowser/#/R-SSC-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 30031 R-SSC-1234173 https://reactome.org/PathwayBrowser/#/R-SSC-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 30031 R-SSC-1234177 https://reactome.org/PathwayBrowser/#/R-SSC-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 30031 R-SSC-1234181 https://reactome.org/PathwayBrowser/#/R-SSC-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 30031 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa 30031 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa 30031 R-SSC-2172678 https://reactome.org/PathwayBrowser/#/R-SSC-2172678 PHF8 demethylates histone H4K20me1 IEA Sus scrofa 30031 R-SSC-3222593 https://reactome.org/PathwayBrowser/#/R-SSC-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Sus scrofa 30031 R-SSC-3296244 https://reactome.org/PathwayBrowser/#/R-SSC-3296244 SUCNR1 binds SUCCA IEA Sus scrofa 30031 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 30031 R-SSC-389639 https://reactome.org/PathwayBrowser/#/R-SSC-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Sus scrofa 30031 R-SSC-433101 https://reactome.org/PathwayBrowser/#/R-SSC-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Sus scrofa 30031 R-SSC-433131 https://reactome.org/PathwayBrowser/#/R-SSC-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Sus scrofa 30031 R-SSC-4722133 https://reactome.org/PathwayBrowser/#/R-SSC-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Sus scrofa 30031 R-SSC-4724279 https://reactome.org/PathwayBrowser/#/R-SSC-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Sus scrofa 30031 R-SSC-4724284 https://reactome.org/PathwayBrowser/#/R-SSC-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Sus scrofa 30031 R-SSC-4754176 https://reactome.org/PathwayBrowser/#/R-SSC-4754176 JMJD6 demethylates MeR3-histone H3 IEA Sus scrofa 30031 R-SSC-4754181 https://reactome.org/PathwayBrowser/#/R-SSC-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Sus scrofa 30031 R-SSC-4754187 https://reactome.org/PathwayBrowser/#/R-SSC-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Sus scrofa 30031 R-SSC-5423117 https://reactome.org/PathwayBrowser/#/R-SSC-5423117 PHF8 demethylates MeK21-histone H4 IEA Sus scrofa 30031 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 30031 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 30031 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 30031 R-SSC-5661114 https://reactome.org/PathwayBrowser/#/R-SSC-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Sus scrofa 30031 R-SSC-5661115 https://reactome.org/PathwayBrowser/#/R-SSC-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Sus scrofa 30031 R-SSC-5661116 https://reactome.org/PathwayBrowser/#/R-SSC-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Sus scrofa 30031 R-SSC-5661120 https://reactome.org/PathwayBrowser/#/R-SSC-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Sus scrofa 30031 R-SSC-5661121 https://reactome.org/PathwayBrowser/#/R-SSC-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Sus scrofa 30031 R-SSC-5661122 https://reactome.org/PathwayBrowser/#/R-SSC-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Sus scrofa 30031 R-SSC-5661124 https://reactome.org/PathwayBrowser/#/R-SSC-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Sus scrofa 30031 R-SSC-5661125 https://reactome.org/PathwayBrowser/#/R-SSC-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Sus scrofa 30031 R-SSC-70994 https://reactome.org/PathwayBrowser/#/R-SSC-70994 SDH complex dehydrogenates succinate IEA Sus scrofa 30031 R-SSC-70997 https://reactome.org/PathwayBrowser/#/R-SSC-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Sus scrofa 30031 R-SSC-71241 https://reactome.org/PathwayBrowser/#/R-SSC-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Sus scrofa 30031 R-SSC-71261 https://reactome.org/PathwayBrowser/#/R-SSC-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Sus scrofa 30031 R-SSC-71775 https://reactome.org/PathwayBrowser/#/R-SSC-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Sus scrofa 30031 R-SSC-74177 https://reactome.org/PathwayBrowser/#/R-SSC-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Sus scrofa 30031 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 30031 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 30031 R-SSC-8857692 https://reactome.org/PathwayBrowser/#/R-SSC-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Sus scrofa 30031 R-SSC-888548 https://reactome.org/PathwayBrowser/#/R-SSC-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Sus scrofa 30031 R-SSC-9629578 https://reactome.org/PathwayBrowser/#/R-SSC-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Sus scrofa 30031 R-SSC-9629591 https://reactome.org/PathwayBrowser/#/R-SSC-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Sus scrofa 30031 R-SSC-9629869 https://reactome.org/PathwayBrowser/#/R-SSC-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Sus scrofa 30031 R-SSC-9629888 https://reactome.org/PathwayBrowser/#/R-SSC-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Sus scrofa 30031 R-SSC-9629946 https://reactome.org/PathwayBrowser/#/R-SSC-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Sus scrofa 30031 R-SSC-9630022 https://reactome.org/PathwayBrowser/#/R-SSC-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Sus scrofa 30031 R-SSC-9630769 https://reactome.org/PathwayBrowser/#/R-SSC-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Sus scrofa 30031 R-SSC-9630967 https://reactome.org/PathwayBrowser/#/R-SSC-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Sus scrofa 30031 R-SSC-9630993 https://reactome.org/PathwayBrowser/#/R-SSC-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Sus scrofa 30031 R-XTR-1234164 https://reactome.org/PathwayBrowser/#/R-XTR-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Xenopus tropicalis 30031 R-XTR-1234165 https://reactome.org/PathwayBrowser/#/R-XTR-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 30031 R-XTR-1234173 https://reactome.org/PathwayBrowser/#/R-XTR-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 30031 R-XTR-1234177 https://reactome.org/PathwayBrowser/#/R-XTR-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 30031 R-XTR-1234181 https://reactome.org/PathwayBrowser/#/R-XTR-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 30031 R-XTR-1650808 https://reactome.org/PathwayBrowser/#/R-XTR-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Xenopus tropicalis 30031 R-XTR-1980233 https://reactome.org/PathwayBrowser/#/R-XTR-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Xenopus tropicalis 30031 R-XTR-1981104 https://reactome.org/PathwayBrowser/#/R-XTR-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Xenopus tropicalis 30031 R-XTR-2172678 https://reactome.org/PathwayBrowser/#/R-XTR-2172678 PHF8 demethylates histone H4K20me1 IEA Xenopus tropicalis 30031 R-XTR-3222593 https://reactome.org/PathwayBrowser/#/R-XTR-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Xenopus tropicalis 30031 R-XTR-389639 https://reactome.org/PathwayBrowser/#/R-XTR-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Xenopus tropicalis 30031 R-XTR-433101 https://reactome.org/PathwayBrowser/#/R-XTR-433101 NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion IEA Xenopus tropicalis 30031 R-XTR-433131 https://reactome.org/PathwayBrowser/#/R-XTR-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Xenopus tropicalis 30031 R-XTR-70994 https://reactome.org/PathwayBrowser/#/R-XTR-70994 SDH complex dehydrogenates succinate IEA Xenopus tropicalis 30031 R-XTR-70997 https://reactome.org/PathwayBrowser/#/R-XTR-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Xenopus tropicalis 30031 R-XTR-71241 https://reactome.org/PathwayBrowser/#/R-XTR-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Xenopus tropicalis 30031 R-XTR-71261 https://reactome.org/PathwayBrowser/#/R-XTR-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Xenopus tropicalis 30031 R-XTR-71775 https://reactome.org/PathwayBrowser/#/R-XTR-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Xenopus tropicalis 30031 R-XTR-74177 https://reactome.org/PathwayBrowser/#/R-XTR-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Xenopus tropicalis 30031 R-XTR-8857692 https://reactome.org/PathwayBrowser/#/R-XTR-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Xenopus tropicalis 30031 R-XTR-888548 https://reactome.org/PathwayBrowser/#/R-XTR-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Xenopus tropicalis 30031 R-XTR-9629578 https://reactome.org/PathwayBrowser/#/R-XTR-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Xenopus tropicalis 30031 R-XTR-9629591 https://reactome.org/PathwayBrowser/#/R-XTR-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Xenopus tropicalis 30031 R-XTR-9629869 https://reactome.org/PathwayBrowser/#/R-XTR-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Xenopus tropicalis 30031 R-XTR-9629888 https://reactome.org/PathwayBrowser/#/R-XTR-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Xenopus tropicalis 30031 R-XTR-9630022 https://reactome.org/PathwayBrowser/#/R-XTR-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Xenopus tropicalis 30031 R-XTR-9630769 https://reactome.org/PathwayBrowser/#/R-XTR-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Xenopus tropicalis 30031 R-XTR-9630993 https://reactome.org/PathwayBrowser/#/R-XTR-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Xenopus tropicalis 30065 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 30065 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 30065 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 30065 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 30065 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 30065 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 30065 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 30065 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 30065 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 30089 R-BTA-3769447 https://reactome.org/PathwayBrowser/#/R-BTA-3769447 HDAC1:2-containing complex deacetylate histones IEA Bos taurus 30089 R-BTA-3777129 https://reactome.org/PathwayBrowser/#/R-BTA-3777129 HDAC3 containing complexes deacetylate histone IEA Bos taurus 30089 R-BTA-3782637 https://reactome.org/PathwayBrowser/#/R-BTA-3782637 HDAC8 deacetylates histones IEA Bos taurus 30089 R-BTA-3782655 https://reactome.org/PathwayBrowser/#/R-BTA-3782655 HDAC10 deacetylates histone IEA Bos taurus 30089 R-BTA-449911 https://reactome.org/PathwayBrowser/#/R-BTA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Bos taurus 30089 R-BTA-5696091 https://reactome.org/PathwayBrowser/#/R-BTA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Bos taurus 30089 R-BTA-6805650 https://reactome.org/PathwayBrowser/#/R-BTA-6805650 MTA2-NuRD complex deacetylates TP53 IEA Bos taurus 30089 R-BTA-71723 https://reactome.org/PathwayBrowser/#/R-BTA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Bos taurus 30089 R-BTA-8875071 https://reactome.org/PathwayBrowser/#/R-BTA-8875071 ACSS3 ligates CoA to CH3COO- IEA Bos taurus 30089 R-BTA-9749609 https://reactome.org/PathwayBrowser/#/R-BTA-9749609 BCHE hydrolyzes ASA- IEA Bos taurus 30089 R-BTA-9749647 https://reactome.org/PathwayBrowser/#/R-BTA-9749647 CES2 hydrolyzes ASA- IEA Bos taurus 30089 R-BTA-9749792 https://reactome.org/PathwayBrowser/#/R-BTA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Bos taurus 30089 R-BTA-9753944 https://reactome.org/PathwayBrowser/#/R-BTA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Bos taurus 30089 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 30089 R-CEL-5696091 https://reactome.org/PathwayBrowser/#/R-CEL-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Caenorhabditis elegans 30089 R-CEL-6805650 https://reactome.org/PathwayBrowser/#/R-CEL-6805650 MTA2-NuRD complex deacetylates TP53 IEA Caenorhabditis elegans 30089 R-CEL-71723 https://reactome.org/PathwayBrowser/#/R-CEL-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Caenorhabditis elegans 30089 R-CEL-9749609 https://reactome.org/PathwayBrowser/#/R-CEL-9749609 BCHE hydrolyzes ASA- IEA Caenorhabditis elegans 30089 R-CEL-9749647 https://reactome.org/PathwayBrowser/#/R-CEL-9749647 CES2 hydrolyzes ASA- IEA Caenorhabditis elegans 30089 R-CEL-9749792 https://reactome.org/PathwayBrowser/#/R-CEL-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Caenorhabditis elegans 30089 R-CEL-9753944 https://reactome.org/PathwayBrowser/#/R-CEL-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Caenorhabditis elegans 30089 R-CFA-3769447 https://reactome.org/PathwayBrowser/#/R-CFA-3769447 HDAC1:2-containing complex deacetylate histones IEA Canis familiaris 30089 R-CFA-3777129 https://reactome.org/PathwayBrowser/#/R-CFA-3777129 HDAC3 containing complexes deacetylate histone IEA Canis familiaris 30089 R-CFA-3782637 https://reactome.org/PathwayBrowser/#/R-CFA-3782637 HDAC8 deacetylates histones IEA Canis familiaris 30089 R-CFA-3782655 https://reactome.org/PathwayBrowser/#/R-CFA-3782655 HDAC10 deacetylates histone IEA Canis familiaris 30089 R-CFA-449911 https://reactome.org/PathwayBrowser/#/R-CFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Canis familiaris 30089 R-CFA-5696091 https://reactome.org/PathwayBrowser/#/R-CFA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Canis familiaris 30089 R-CFA-6805650 https://reactome.org/PathwayBrowser/#/R-CFA-6805650 MTA2-NuRD complex deacetylates TP53 IEA Canis familiaris 30089 R-CFA-71723 https://reactome.org/PathwayBrowser/#/R-CFA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Canis familiaris 30089 R-CFA-8875071 https://reactome.org/PathwayBrowser/#/R-CFA-8875071 ACSS3 ligates CoA to CH3COO- IEA Canis familiaris 30089 R-CFA-9749609 https://reactome.org/PathwayBrowser/#/R-CFA-9749609 BCHE hydrolyzes ASA- IEA Canis familiaris 30089 R-CFA-9749647 https://reactome.org/PathwayBrowser/#/R-CFA-9749647 CES2 hydrolyzes ASA- IEA Canis familiaris 30089 R-CFA-9749792 https://reactome.org/PathwayBrowser/#/R-CFA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Canis familiaris 30089 R-CFA-9753944 https://reactome.org/PathwayBrowser/#/R-CFA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Canis familiaris 30089 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 30089 R-DDI-3769447 https://reactome.org/PathwayBrowser/#/R-DDI-3769447 HDAC1:2-containing complex deacetylate histones IEA Dictyostelium discoideum 30089 R-DDI-3782637 https://reactome.org/PathwayBrowser/#/R-DDI-3782637 HDAC8 deacetylates histones IEA Dictyostelium discoideum 30089 R-DDI-3782655 https://reactome.org/PathwayBrowser/#/R-DDI-3782655 HDAC10 deacetylates histone IEA Dictyostelium discoideum 30089 R-DDI-449911 https://reactome.org/PathwayBrowser/#/R-DDI-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Dictyostelium discoideum 30089 R-DDI-5696091 https://reactome.org/PathwayBrowser/#/R-DDI-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Dictyostelium discoideum 30089 R-DDI-71723 https://reactome.org/PathwayBrowser/#/R-DDI-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Dictyostelium discoideum 30089 R-DDI-8875071 https://reactome.org/PathwayBrowser/#/R-DDI-8875071 ACSS3 ligates CoA to CH3COO- IEA Dictyostelium discoideum 30089 R-DDI-9749647 https://reactome.org/PathwayBrowser/#/R-DDI-9749647 CES2 hydrolyzes ASA- IEA Dictyostelium discoideum 30089 R-DDI-9749792 https://reactome.org/PathwayBrowser/#/R-DDI-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Dictyostelium discoideum 30089 R-DDI-9753944 https://reactome.org/PathwayBrowser/#/R-DDI-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Dictyostelium discoideum 30089 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 30089 R-DME-3769447 https://reactome.org/PathwayBrowser/#/R-DME-3769447 HDAC1:2-containing complex deacetylate histones IEA Drosophila melanogaster 30089 R-DME-3777129 https://reactome.org/PathwayBrowser/#/R-DME-3777129 HDAC3 containing complexes deacetylate histone IEA Drosophila melanogaster 30089 R-DME-3782655 https://reactome.org/PathwayBrowser/#/R-DME-3782655 HDAC10 deacetylates histone IEA Drosophila melanogaster 30089 R-DME-5696091 https://reactome.org/PathwayBrowser/#/R-DME-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Drosophila melanogaster 30089 R-DME-6805650 https://reactome.org/PathwayBrowser/#/R-DME-6805650 MTA2-NuRD complex deacetylates TP53 IEA Drosophila melanogaster 30089 R-DME-71723 https://reactome.org/PathwayBrowser/#/R-DME-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Drosophila melanogaster 30089 R-DME-8875071 https://reactome.org/PathwayBrowser/#/R-DME-8875071 ACSS3 ligates CoA to CH3COO- IEA Drosophila melanogaster 30089 R-DME-9749609 https://reactome.org/PathwayBrowser/#/R-DME-9749609 BCHE hydrolyzes ASA- IEA Drosophila melanogaster 30089 R-DME-9749647 https://reactome.org/PathwayBrowser/#/R-DME-9749647 CES2 hydrolyzes ASA- IEA Drosophila melanogaster 30089 R-DME-9749792 https://reactome.org/PathwayBrowser/#/R-DME-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Drosophila melanogaster 30089 R-DME-9753944 https://reactome.org/PathwayBrowser/#/R-DME-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Drosophila melanogaster 30089 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 30089 R-DRE-3782637 https://reactome.org/PathwayBrowser/#/R-DRE-3782637 HDAC8 deacetylates histones IEA Danio rerio 30089 R-DRE-3782655 https://reactome.org/PathwayBrowser/#/R-DRE-3782655 HDAC10 deacetylates histone IEA Danio rerio 30089 R-DRE-5696091 https://reactome.org/PathwayBrowser/#/R-DRE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Danio rerio 30089 R-DRE-71723 https://reactome.org/PathwayBrowser/#/R-DRE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Danio rerio 30089 R-DRE-9749647 https://reactome.org/PathwayBrowser/#/R-DRE-9749647 CES2 hydrolyzes ASA- IEA Danio rerio 30089 R-DRE-9749792 https://reactome.org/PathwayBrowser/#/R-DRE-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Danio rerio 30089 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 30089 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus 30089 R-GGA-3777129 https://reactome.org/PathwayBrowser/#/R-GGA-3777129 HDAC3 containing complexes deacetylate histone IEA Gallus gallus 30089 R-GGA-3782637 https://reactome.org/PathwayBrowser/#/R-GGA-3782637 HDAC8 deacetylates histones IEA Gallus gallus 30089 R-GGA-3782655 https://reactome.org/PathwayBrowser/#/R-GGA-3782655 HDAC10 deacetylates histone IEA Gallus gallus 30089 R-GGA-449911 https://reactome.org/PathwayBrowser/#/R-GGA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Gallus gallus 30089 R-GGA-71723 https://reactome.org/PathwayBrowser/#/R-GGA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Gallus gallus 30089 R-GGA-8875071 https://reactome.org/PathwayBrowser/#/R-GGA-8875071 ACSS3 ligates CoA to CH3COO- IEA Gallus gallus 30089 R-GGA-9749609 https://reactome.org/PathwayBrowser/#/R-GGA-9749609 BCHE hydrolyzes ASA- IEA Gallus gallus 30089 R-GGA-9749647 https://reactome.org/PathwayBrowser/#/R-GGA-9749647 CES2 hydrolyzes ASA- IEA Gallus gallus 30089 R-GGA-9749792 https://reactome.org/PathwayBrowser/#/R-GGA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Gallus gallus 30089 R-GGA-9753944 https://reactome.org/PathwayBrowser/#/R-GGA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Gallus gallus 30089 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 30089 R-HSA-3769447 https://reactome.org/PathwayBrowser/#/R-HSA-3769447 HDAC1:2-containing complex deacetylate histones TAS Homo sapiens 30089 R-HSA-3777129 https://reactome.org/PathwayBrowser/#/R-HSA-3777129 HDAC3 containing complexes deacetylate histone TAS Homo sapiens 30089 R-HSA-3782637 https://reactome.org/PathwayBrowser/#/R-HSA-3782637 HDAC8 deacetylates histones TAS Homo sapiens 30089 R-HSA-3782655 https://reactome.org/PathwayBrowser/#/R-HSA-3782655 HDAC10 deacetylates histone TAS Homo sapiens 30089 R-HSA-449911 https://reactome.org/PathwayBrowser/#/R-HSA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] TAS Homo sapiens 30089 R-HSA-5696091 https://reactome.org/PathwayBrowser/#/R-HSA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH TAS Homo sapiens 30089 R-HSA-6805650 https://reactome.org/PathwayBrowser/#/R-HSA-6805650 MTA2-NuRD complex deacetylates TP53 TAS Homo sapiens 30089 R-HSA-71723 https://reactome.org/PathwayBrowser/#/R-HSA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] TAS Homo sapiens 30089 R-HSA-8875071 https://reactome.org/PathwayBrowser/#/R-HSA-8875071 ACSS3 ligates CoA to CH3COO- TAS Homo sapiens 30089 R-HSA-9749609 https://reactome.org/PathwayBrowser/#/R-HSA-9749609 BCHE hydrolyzes ASA- TAS Homo sapiens 30089 R-HSA-9749647 https://reactome.org/PathwayBrowser/#/R-HSA-9749647 CES2 hydrolyzes ASA- TAS Homo sapiens 30089 R-HSA-9749792 https://reactome.org/PathwayBrowser/#/R-HSA-9749792 CES1,CES2 hydrolyze ASA- to ST TAS Homo sapiens 30089 R-HSA-9753944 https://reactome.org/PathwayBrowser/#/R-HSA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys TAS Homo sapiens 30089 R-HSA-9861595 https://reactome.org/PathwayBrowser/#/R-HSA-9861595 Cytosolic H2O2 decarboxylates PYR to acetate TAS Homo sapiens 30089 R-HSA-9861745 https://reactome.org/PathwayBrowser/#/R-HSA-9861745 Mitochondrial H2O2 decarboxylates PYR to acetate TAS Homo sapiens 30089 R-MMU-3769447 https://reactome.org/PathwayBrowser/#/R-MMU-3769447 HDAC1:2-containing complex deacetylate histones IEA Mus musculus 30089 R-MMU-3777129 https://reactome.org/PathwayBrowser/#/R-MMU-3777129 HDAC3 containing complexes deacetylate histone IEA Mus musculus 30089 R-MMU-3782637 https://reactome.org/PathwayBrowser/#/R-MMU-3782637 HDAC8 deacetylates histones IEA Mus musculus 30089 R-MMU-3782655 https://reactome.org/PathwayBrowser/#/R-MMU-3782655 HDAC10 deacetylates histone IEA Mus musculus 30089 R-MMU-449911 https://reactome.org/PathwayBrowser/#/R-MMU-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Mus musculus 30089 R-MMU-5696091 https://reactome.org/PathwayBrowser/#/R-MMU-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Mus musculus 30089 R-MMU-6805650 https://reactome.org/PathwayBrowser/#/R-MMU-6805650 MTA2-NuRD complex deacetylates TP53 IEA Mus musculus 30089 R-MMU-71723 https://reactome.org/PathwayBrowser/#/R-MMU-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Mus musculus 30089 R-MMU-8875071 https://reactome.org/PathwayBrowser/#/R-MMU-8875071 ACSS3 ligates CoA to CH3COO- IEA Mus musculus 30089 R-MMU-9749609 https://reactome.org/PathwayBrowser/#/R-MMU-9749609 BCHE hydrolyzes ASA- IEA Mus musculus 30089 R-MMU-9749647 https://reactome.org/PathwayBrowser/#/R-MMU-9749647 CES2 hydrolyzes ASA- IEA Mus musculus 30089 R-MMU-9749792 https://reactome.org/PathwayBrowser/#/R-MMU-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Mus musculus 30089 R-MMU-9753944 https://reactome.org/PathwayBrowser/#/R-MMU-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Mus musculus 30089 R-PFA-3782637 https://reactome.org/PathwayBrowser/#/R-PFA-3782637 HDAC8 deacetylates histones IEA Plasmodium falciparum 30089 R-PFA-3782655 https://reactome.org/PathwayBrowser/#/R-PFA-3782655 HDAC10 deacetylates histone IEA Plasmodium falciparum 30089 R-PFA-449911 https://reactome.org/PathwayBrowser/#/R-PFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Plasmodium falciparum 30089 R-RNO-449911 https://reactome.org/PathwayBrowser/#/R-RNO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Rattus norvegicus 30089 R-RNO-5696091 https://reactome.org/PathwayBrowser/#/R-RNO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Rattus norvegicus 30089 R-RNO-6805650 https://reactome.org/PathwayBrowser/#/R-RNO-6805650 MTA2-NuRD complex deacetylates TP53 IEA Rattus norvegicus 30089 R-RNO-71723 https://reactome.org/PathwayBrowser/#/R-RNO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Rattus norvegicus 30089 R-RNO-8875071 https://reactome.org/PathwayBrowser/#/R-RNO-8875071 ACSS3 ligates CoA to CH3COO- IEA Rattus norvegicus 30089 R-RNO-9749609 https://reactome.org/PathwayBrowser/#/R-RNO-9749609 BCHE hydrolyzes ASA- IEA Rattus norvegicus 30089 R-RNO-9749647 https://reactome.org/PathwayBrowser/#/R-RNO-9749647 CES2 hydrolyzes ASA- IEA Rattus norvegicus 30089 R-RNO-9749792 https://reactome.org/PathwayBrowser/#/R-RNO-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Rattus norvegicus 30089 R-RNO-9753944 https://reactome.org/PathwayBrowser/#/R-RNO-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Rattus norvegicus 30089 R-SCE-3769447 https://reactome.org/PathwayBrowser/#/R-SCE-3769447 HDAC1:2-containing complex deacetylate histones IEA Saccharomyces cerevisiae 30089 R-SCE-3777129 https://reactome.org/PathwayBrowser/#/R-SCE-3777129 HDAC3 containing complexes deacetylate histone IEA Saccharomyces cerevisiae 30089 R-SCE-3782637 https://reactome.org/PathwayBrowser/#/R-SCE-3782637 HDAC8 deacetylates histones IEA Saccharomyces cerevisiae 30089 R-SCE-3782655 https://reactome.org/PathwayBrowser/#/R-SCE-3782655 HDAC10 deacetylates histone IEA Saccharomyces cerevisiae 30089 R-SCE-449911 https://reactome.org/PathwayBrowser/#/R-SCE-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Saccharomyces cerevisiae 30089 R-SCE-5696091 https://reactome.org/PathwayBrowser/#/R-SCE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Saccharomyces cerevisiae 30089 R-SCE-71723 https://reactome.org/PathwayBrowser/#/R-SCE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Saccharomyces cerevisiae 30089 R-SPO-3769447 https://reactome.org/PathwayBrowser/#/R-SPO-3769447 HDAC1:2-containing complex deacetylate histones IEA Schizosaccharomyces pombe 30089 R-SPO-3782655 https://reactome.org/PathwayBrowser/#/R-SPO-3782655 HDAC10 deacetylates histone IEA Schizosaccharomyces pombe 30089 R-SPO-449911 https://reactome.org/PathwayBrowser/#/R-SPO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Schizosaccharomyces pombe 30089 R-SPO-5696091 https://reactome.org/PathwayBrowser/#/R-SPO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Schizosaccharomyces pombe 30089 R-SPO-71723 https://reactome.org/PathwayBrowser/#/R-SPO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Schizosaccharomyces pombe 30089 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 30089 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa 30089 R-SSC-3777129 https://reactome.org/PathwayBrowser/#/R-SSC-3777129 HDAC3 containing complexes deacetylate histone IEA Sus scrofa 30089 R-SSC-3782637 https://reactome.org/PathwayBrowser/#/R-SSC-3782637 HDAC8 deacetylates histones IEA Sus scrofa 30089 R-SSC-3782655 https://reactome.org/PathwayBrowser/#/R-SSC-3782655 HDAC10 deacetylates histone IEA Sus scrofa 30089 R-SSC-449911 https://reactome.org/PathwayBrowser/#/R-SSC-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Sus scrofa 30089 R-SSC-5696091 https://reactome.org/PathwayBrowser/#/R-SSC-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Sus scrofa 30089 R-SSC-6805650 https://reactome.org/PathwayBrowser/#/R-SSC-6805650 MTA2-NuRD complex deacetylates TP53 IEA Sus scrofa 30089 R-SSC-71723 https://reactome.org/PathwayBrowser/#/R-SSC-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Sus scrofa 30089 R-SSC-8875071 https://reactome.org/PathwayBrowser/#/R-SSC-8875071 ACSS3 ligates CoA to CH3COO- IEA Sus scrofa 30089 R-SSC-9749792 https://reactome.org/PathwayBrowser/#/R-SSC-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Sus scrofa 30089 R-SSC-9753944 https://reactome.org/PathwayBrowser/#/R-SSC-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Sus scrofa 30089 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 30089 R-XTR-449911 https://reactome.org/PathwayBrowser/#/R-XTR-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Xenopus tropicalis 30089 R-XTR-5696091 https://reactome.org/PathwayBrowser/#/R-XTR-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Xenopus tropicalis 30089 R-XTR-6805650 https://reactome.org/PathwayBrowser/#/R-XTR-6805650 MTA2-NuRD complex deacetylates TP53 IEA Xenopus tropicalis 30089 R-XTR-71723 https://reactome.org/PathwayBrowser/#/R-XTR-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Xenopus tropicalis 30089 R-XTR-8875071 https://reactome.org/PathwayBrowser/#/R-XTR-8875071 ACSS3 ligates CoA to CH3COO- IEA Xenopus tropicalis 30089 R-XTR-9749609 https://reactome.org/PathwayBrowser/#/R-XTR-9749609 BCHE hydrolyzes ASA- IEA Xenopus tropicalis 30089 R-XTR-9749792 https://reactome.org/PathwayBrowser/#/R-XTR-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Xenopus tropicalis 30089 R-XTR-9753944 https://reactome.org/PathwayBrowser/#/R-XTR-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Xenopus tropicalis 3011 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 3011 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 3011 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 3011 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 3011 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 3011 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 3011 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 3011 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 3011 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 3011 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 3011 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 3011 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 30212 R-BTA-2465917 https://reactome.org/PathwayBrowser/#/R-BTA-2465917 Photons induce isomerisation of 11c-retinyl to at-retinyl IEA Bos taurus 30212 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 30212 R-BTA-419841 https://reactome.org/PathwayBrowser/#/R-BTA-419841 Light stimulates opsin receptors IEA Bos taurus 30212 R-BTA-419861 https://reactome.org/PathwayBrowser/#/R-BTA-419861 Melanospin is stimulated by light IEA Bos taurus 30212 R-BTA-420883 https://reactome.org/PathwayBrowser/#/R-BTA-420883 Opsins act as GEFs for G alpha-t IEA Bos taurus 30212 R-BTA-74101 https://reactome.org/PathwayBrowser/#/R-BTA-74101 Photons induce isomerization of 11c-retinyl to at-retinyl IEA Bos taurus 30212 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 30212 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 30212 R-BTA-8982637 https://reactome.org/PathwayBrowser/#/R-BTA-8982637 Opsins binds G alpha-t IEA Bos taurus 30212 R-BTA-8982640 https://reactome.org/PathwayBrowser/#/R-BTA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Bos taurus 30212 R-CEL-2465917 https://reactome.org/PathwayBrowser/#/R-CEL-2465917 Photons induce isomerisation of 11c-retinyl to at-retinyl IEA Caenorhabditis elegans 30212 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 30212 R-CEL-419841 https://reactome.org/PathwayBrowser/#/R-CEL-419841 Light stimulates opsin receptors IEA Caenorhabditis elegans 30212 R-CEL-419861 https://reactome.org/PathwayBrowser/#/R-CEL-419861 Melanospin is stimulated by light IEA Caenorhabditis elegans 30212 R-CEL-420883 https://reactome.org/PathwayBrowser/#/R-CEL-420883 Opsins act as GEFs for G alpha-t IEA Caenorhabditis elegans 30212 R-CEL-74101 https://reactome.org/PathwayBrowser/#/R-CEL-74101 Photons induce isomerization of 11c-retinyl to at-retinyl IEA Caenorhabditis elegans 30212 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 30212 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 30212 R-CFA-2465917 https://reactome.org/PathwayBrowser/#/R-CFA-2465917 Photons induce isomerisation of 11c-retinyl to at-retinyl IEA Canis familiaris 30212 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 30212 R-CFA-419841 https://reactome.org/PathwayBrowser/#/R-CFA-419841 Light stimulates opsin receptors IEA Canis familiaris 30212 R-CFA-419861 https://reactome.org/PathwayBrowser/#/R-CFA-419861 Melanospin is stimulated by light IEA Canis familiaris 30212 R-CFA-420883 https://reactome.org/PathwayBrowser/#/R-CFA-420883 Opsins act as GEFs for G alpha-t IEA Canis familiaris 30212 R-CFA-74101 https://reactome.org/PathwayBrowser/#/R-CFA-74101 Photons induce isomerization of 11c-retinyl to at-retinyl IEA Canis familiaris 30212 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 30212 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 30212 R-CFA-8982637 https://reactome.org/PathwayBrowser/#/R-CFA-8982637 Opsins binds G alpha-t IEA Canis familiaris 30212 R-CFA-8982640 https://reactome.org/PathwayBrowser/#/R-CFA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Canis familiaris 30212 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 30212 R-DME-419861 https://reactome.org/PathwayBrowser/#/R-DME-419861 Melanospin is stimulated by light IEA Drosophila melanogaster 30212 R-DME-432371 https://reactome.org/PathwayBrowser/#/R-DME-432371 CRY is activated by light and binds to phosphorylated nuclear TIM TAS Drosophila melanogaster 30212 R-DME-432426 https://reactome.org/PathwayBrowser/#/R-DME-432426 CRY is activated by light and binds to cytosolic TIM TAS Drosophila melanogaster 30212 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 30212 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 30212 R-DRE-2465917 https://reactome.org/PathwayBrowser/#/R-DRE-2465917 Photons induce isomerisation of 11c-retinyl to at-retinyl IEA Danio rerio 30212 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 30212 R-DRE-419841 https://reactome.org/PathwayBrowser/#/R-DRE-419841 Light stimulates opsin receptors IEA Danio rerio 30212 R-DRE-419861 https://reactome.org/PathwayBrowser/#/R-DRE-419861 Melanospin is stimulated by light IEA Danio rerio 30212 R-DRE-420883 https://reactome.org/PathwayBrowser/#/R-DRE-420883 Opsins act as GEFs for G alpha-t IEA Danio rerio 30212 R-DRE-74101 https://reactome.org/PathwayBrowser/#/R-DRE-74101 Photons induce isomerization of 11c-retinyl to at-retinyl IEA Danio rerio 30212 R-GGA-2465917 https://reactome.org/PathwayBrowser/#/R-GGA-2465917 Photons induce isomerisation of 11c-retinyl to at-retinyl IEA Gallus gallus 30212 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 30212 R-GGA-419841 https://reactome.org/PathwayBrowser/#/R-GGA-419841 Light stimulates opsin receptors IEA Gallus gallus 30212 R-GGA-419861 https://reactome.org/PathwayBrowser/#/R-GGA-419861 Melanospin is stimulated by light IEA Gallus gallus 30212 R-GGA-420883 https://reactome.org/PathwayBrowser/#/R-GGA-420883 Opsins act as GEFs for G alpha-t IEA Gallus gallus 30212 R-GGA-74101 https://reactome.org/PathwayBrowser/#/R-GGA-74101 Photons induce isomerization of 11c-retinyl to at-retinyl IEA Gallus gallus 30212 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 30212 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 30212 R-GGA-8982637 https://reactome.org/PathwayBrowser/#/R-GGA-8982637 Opsins binds G alpha-t IEA Gallus gallus 30212 R-GGA-8982640 https://reactome.org/PathwayBrowser/#/R-GGA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Gallus gallus 30212 R-HSA-2465917 https://reactome.org/PathwayBrowser/#/R-HSA-2465917 Photons induce isomerisation of 11c-retinyl to at-retinyl TAS Homo sapiens 30212 R-HSA-3785704 https://reactome.org/PathwayBrowser/#/R-HSA-3785704 DSB inducing agents induce double strand DNA breaks TAS Homo sapiens 30212 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 30212 R-HSA-419841 https://reactome.org/PathwayBrowser/#/R-HSA-419841 Light stimulates opsin receptors TAS Homo sapiens 30212 R-HSA-419861 https://reactome.org/PathwayBrowser/#/R-HSA-419861 Melanospin is stimulated by light TAS Homo sapiens 30212 R-HSA-420883 https://reactome.org/PathwayBrowser/#/R-HSA-420883 Opsins act as GEFs for G alpha-t TAS Homo sapiens 30212 R-HSA-74101 https://reactome.org/PathwayBrowser/#/R-HSA-74101 Photons induce isomerization of 11c-retinyl to at-retinyl TAS Homo sapiens 30212 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 30212 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 30212 R-HSA-8982637 https://reactome.org/PathwayBrowser/#/R-HSA-8982637 Opsins binds G alpha-t TAS Homo sapiens 30212 R-HSA-8982640 https://reactome.org/PathwayBrowser/#/R-HSA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) TAS Homo sapiens 30212 R-HSA-9713837 https://reactome.org/PathwayBrowser/#/R-HSA-9713837 Psoralens in combination with UV generate DNA interstrand crosslinks TAS Homo sapiens 30212 R-MMU-2465917 https://reactome.org/PathwayBrowser/#/R-MMU-2465917 Photons induce isomerisation of 11c-retinyl to at-retinyl IEA Mus musculus 30212 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 30212 R-MMU-419841 https://reactome.org/PathwayBrowser/#/R-MMU-419841 Light stimulates opsin receptors IEA Mus musculus 30212 R-MMU-419861 https://reactome.org/PathwayBrowser/#/R-MMU-419861 Melanospin is stimulated by light IEA Mus musculus 30212 R-MMU-420883 https://reactome.org/PathwayBrowser/#/R-MMU-420883 Opsins act as GEFs for G alpha-t IEA Mus musculus 30212 R-MMU-74101 https://reactome.org/PathwayBrowser/#/R-MMU-74101 Photons induce isomerization of 11c-retinyl to at-retinyl IEA Mus musculus 30212 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 30212 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 30212 R-MMU-8982637 https://reactome.org/PathwayBrowser/#/R-MMU-8982637 Opsins binds G alpha-t IEA Mus musculus 30212 R-MMU-8982640 https://reactome.org/PathwayBrowser/#/R-MMU-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Mus musculus 30212 R-RNO-2465917 https://reactome.org/PathwayBrowser/#/R-RNO-2465917 Photons induce isomerisation of 11c-retinyl to at-retinyl IEA Rattus norvegicus 30212 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 30212 R-RNO-419841 https://reactome.org/PathwayBrowser/#/R-RNO-419841 Light stimulates opsin receptors IEA Rattus norvegicus 30212 R-RNO-419861 https://reactome.org/PathwayBrowser/#/R-RNO-419861 Melanospin is stimulated by light IEA Rattus norvegicus 30212 R-RNO-420883 https://reactome.org/PathwayBrowser/#/R-RNO-420883 Opsins act as GEFs for G alpha-t IEA Rattus norvegicus 30212 R-RNO-74101 https://reactome.org/PathwayBrowser/#/R-RNO-74101 Photons induce isomerization of 11c-retinyl to at-retinyl IEA Rattus norvegicus 30212 R-SSC-2465917 https://reactome.org/PathwayBrowser/#/R-SSC-2465917 Photons induce isomerisation of 11c-retinyl to at-retinyl IEA Sus scrofa 30212 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 30212 R-SSC-419841 https://reactome.org/PathwayBrowser/#/R-SSC-419841 Light stimulates opsin receptors IEA Sus scrofa 30212 R-SSC-419861 https://reactome.org/PathwayBrowser/#/R-SSC-419861 Melanospin is stimulated by light IEA Sus scrofa 30212 R-SSC-420883 https://reactome.org/PathwayBrowser/#/R-SSC-420883 Opsins act as GEFs for G alpha-t IEA Sus scrofa 30212 R-SSC-74101 https://reactome.org/PathwayBrowser/#/R-SSC-74101 Photons induce isomerization of 11c-retinyl to at-retinyl IEA Sus scrofa 30212 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 30212 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 30212 R-SSC-8982637 https://reactome.org/PathwayBrowser/#/R-SSC-8982637 Opsins binds G alpha-t IEA Sus scrofa 30212 R-SSC-8982640 https://reactome.org/PathwayBrowser/#/R-SSC-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Sus scrofa 30212 R-XTR-2465917 https://reactome.org/PathwayBrowser/#/R-XTR-2465917 Photons induce isomerisation of 11c-retinyl to at-retinyl IEA Xenopus tropicalis 30212 R-XTR-419841 https://reactome.org/PathwayBrowser/#/R-XTR-419841 Light stimulates opsin receptors IEA Xenopus tropicalis 30212 R-XTR-419861 https://reactome.org/PathwayBrowser/#/R-XTR-419861 Melanospin is stimulated by light IEA Xenopus tropicalis 30212 R-XTR-420883 https://reactome.org/PathwayBrowser/#/R-XTR-420883 Opsins act as GEFs for G alpha-t IEA Xenopus tropicalis 30212 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 30212 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 30212 R-XTR-8982637 https://reactome.org/PathwayBrowser/#/R-XTR-8982637 Opsins binds G alpha-t IEA Xenopus tropicalis 30212 R-XTR-8982640 https://reactome.org/PathwayBrowser/#/R-XTR-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Xenopus tropicalis 30216 R-HSA-3785704 https://reactome.org/PathwayBrowser/#/R-HSA-3785704 DSB inducing agents induce double strand DNA breaks TAS Homo sapiens 30322 R-BTA-141348 https://reactome.org/PathwayBrowser/#/R-BTA-141348 PAO:FAD oxidises NASPM to PTCN IEA Bos taurus 30322 R-BTA-141351 https://reactome.org/PathwayBrowser/#/R-BTA-141351 PAOX:FAD oxidises NASPN to SPM IEA Bos taurus 30322 R-CEL-141348 https://reactome.org/PathwayBrowser/#/R-CEL-141348 PAO:FAD oxidises NASPM to PTCN IEA Caenorhabditis elegans 30322 R-CEL-141351 https://reactome.org/PathwayBrowser/#/R-CEL-141351 PAOX:FAD oxidises NASPN to SPM IEA Caenorhabditis elegans 30322 R-CFA-141348 https://reactome.org/PathwayBrowser/#/R-CFA-141348 PAO:FAD oxidises NASPM to PTCN IEA Canis familiaris 30322 R-CFA-141351 https://reactome.org/PathwayBrowser/#/R-CFA-141351 PAOX:FAD oxidises NASPN to SPM IEA Canis familiaris 30322 R-DME-141348 https://reactome.org/PathwayBrowser/#/R-DME-141348 PAO:FAD oxidises NASPM to PTCN IEA Drosophila melanogaster 30322 R-DME-141351 https://reactome.org/PathwayBrowser/#/R-DME-141351 PAOX:FAD oxidises NASPN to SPM IEA Drosophila melanogaster 30322 R-DRE-141348 https://reactome.org/PathwayBrowser/#/R-DRE-141348 PAO:FAD oxidises NASPM to PTCN IEA Danio rerio 30322 R-DRE-141351 https://reactome.org/PathwayBrowser/#/R-DRE-141351 PAOX:FAD oxidises NASPN to SPM IEA Danio rerio 30322 R-GGA-141348 https://reactome.org/PathwayBrowser/#/R-GGA-141348 PAO:FAD oxidises NASPM to PTCN IEA Gallus gallus 30322 R-GGA-141351 https://reactome.org/PathwayBrowser/#/R-GGA-141351 PAOX:FAD oxidises NASPN to SPM IEA Gallus gallus 30322 R-HSA-141348 https://reactome.org/PathwayBrowser/#/R-HSA-141348 PAO:FAD oxidises NASPM to PTCN TAS Homo sapiens 30322 R-HSA-141351 https://reactome.org/PathwayBrowser/#/R-HSA-141351 PAOX:FAD oxidises NASPN to SPM TAS Homo sapiens 30322 R-MMU-141348 https://reactome.org/PathwayBrowser/#/R-MMU-141348 PAO:FAD oxidises NASPM to PTCN IEA Mus musculus 30322 R-MMU-141351 https://reactome.org/PathwayBrowser/#/R-MMU-141351 PAOX:FAD oxidises NASPN to SPM IEA Mus musculus 30322 R-RNO-141348 https://reactome.org/PathwayBrowser/#/R-RNO-141348 PAO:FAD oxidises NASPM to PTCN IEA Rattus norvegicus 30322 R-RNO-141351 https://reactome.org/PathwayBrowser/#/R-RNO-141351 PAOX:FAD oxidises NASPN to SPM IEA Rattus norvegicus 30322 R-SSC-141348 https://reactome.org/PathwayBrowser/#/R-SSC-141348 PAO:FAD oxidises NASPM to PTCN IEA Sus scrofa 30322 R-SSC-141351 https://reactome.org/PathwayBrowser/#/R-SSC-141351 PAOX:FAD oxidises NASPN to SPM IEA Sus scrofa 30408 R-BTA-163217 https://reactome.org/PathwayBrowser/#/R-BTA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Bos taurus 30408 R-BTA-5690023 https://reactome.org/PathwayBrowser/#/R-BTA-5690023 NUBPL binds 4Fe-4S IEA Bos taurus 30408 R-BTA-5690873 https://reactome.org/PathwayBrowser/#/R-BTA-5690873 ACO1 binds 4Fe-4S IEA Bos taurus 30408 R-BTA-5690911 https://reactome.org/PathwayBrowser/#/R-BTA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Bos taurus 30408 R-BTA-6788523 https://reactome.org/PathwayBrowser/#/R-BTA-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Bos taurus 30408 R-BTA-6788556 https://reactome.org/PathwayBrowser/#/R-BTA-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Bos taurus 30408 R-BTA-6799178 https://reactome.org/PathwayBrowser/#/R-BTA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Bos taurus 30408 R-BTA-6799179 https://reactome.org/PathwayBrowser/#/R-BTA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Bos taurus 30408 R-BTA-6799191 https://reactome.org/PathwayBrowser/#/R-BTA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Bos taurus 30408 R-BTA-6799196 https://reactome.org/PathwayBrowser/#/R-BTA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Bos taurus 30408 R-BTA-6799197 https://reactome.org/PathwayBrowser/#/R-BTA-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Bos taurus 30408 R-BTA-6799202 https://reactome.org/PathwayBrowser/#/R-BTA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Bos taurus 30408 R-BTA-6799203 https://reactome.org/PathwayBrowser/#/R-BTA-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Bos taurus 30408 R-BTA-6800868 https://reactome.org/PathwayBrowser/#/R-BTA-6800868 NDUF subunits bind to form the IP subcomplex IEA Bos taurus 30408 R-BTA-6800870 https://reactome.org/PathwayBrowser/#/R-BTA-6800870 NDUF subunits bind to form the FP subcomplex IEA Bos taurus 30408 R-BTA-73585 https://reactome.org/PathwayBrowser/#/R-BTA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Bos taurus 30408 R-BTA-73616 https://reactome.org/PathwayBrowser/#/R-BTA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Bos taurus 30408 R-BTA-74247 https://reactome.org/PathwayBrowser/#/R-BTA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Bos taurus 30408 R-BTA-74258 https://reactome.org/PathwayBrowser/#/R-BTA-74258 XDH oxidizes xanthine to form urate IEA Bos taurus 30408 R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 30408 R-BTA-9727349 https://reactome.org/PathwayBrowser/#/R-BTA-9727349 XDH dehydrogenates xanthine to form urate IEA Bos taurus 30408 R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 30408 R-BTA-9854984 https://reactome.org/PathwayBrowser/#/R-BTA-9854984 Transfer of Fe-S clusters to SDHB IEA Bos taurus 30408 R-BTA-9855212 https://reactome.org/PathwayBrowser/#/R-BTA-9855212 SDHA binds to SDHB IEA Bos taurus 30408 R-BTA-9855252 https://reactome.org/PathwayBrowser/#/R-BTA-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Bos taurus 30408 R-CEL-5690873 https://reactome.org/PathwayBrowser/#/R-CEL-5690873 ACO1 binds 4Fe-4S IEA Caenorhabditis elegans 30408 R-CEL-5690911 https://reactome.org/PathwayBrowser/#/R-CEL-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Caenorhabditis elegans 30408 R-CEL-6799178 https://reactome.org/PathwayBrowser/#/R-CEL-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Caenorhabditis elegans 30408 R-CEL-6799191 https://reactome.org/PathwayBrowser/#/R-CEL-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Caenorhabditis elegans 30408 R-CEL-6799197 https://reactome.org/PathwayBrowser/#/R-CEL-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Caenorhabditis elegans 30408 R-CEL-6799203 https://reactome.org/PathwayBrowser/#/R-CEL-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Caenorhabditis elegans 30408 R-CEL-6800868 https://reactome.org/PathwayBrowser/#/R-CEL-6800868 NDUF subunits bind to form the IP subcomplex IEA Caenorhabditis elegans 30408 R-CEL-73585 https://reactome.org/PathwayBrowser/#/R-CEL-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Caenorhabditis elegans 30408 R-CEL-73616 https://reactome.org/PathwayBrowser/#/R-CEL-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Caenorhabditis elegans 30408 R-CEL-74247 https://reactome.org/PathwayBrowser/#/R-CEL-74247 XDH oxidizes hypoxanthine to form xanthine IEA Caenorhabditis elegans 30408 R-CEL-74258 https://reactome.org/PathwayBrowser/#/R-CEL-74258 XDH oxidizes xanthine to form urate IEA Caenorhabditis elegans 30408 R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 30408 R-CEL-9727349 https://reactome.org/PathwayBrowser/#/R-CEL-9727349 XDH dehydrogenates xanthine to form urate IEA Caenorhabditis elegans 30408 R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 30408 R-CFA-163217 https://reactome.org/PathwayBrowser/#/R-CFA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Canis familiaris 30408 R-CFA-5690023 https://reactome.org/PathwayBrowser/#/R-CFA-5690023 NUBPL binds 4Fe-4S IEA Canis familiaris 30408 R-CFA-5690873 https://reactome.org/PathwayBrowser/#/R-CFA-5690873 ACO1 binds 4Fe-4S IEA Canis familiaris 30408 R-CFA-5690911 https://reactome.org/PathwayBrowser/#/R-CFA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Canis familiaris 30408 R-CFA-6788523 https://reactome.org/PathwayBrowser/#/R-CFA-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Canis familiaris 30408 R-CFA-6788556 https://reactome.org/PathwayBrowser/#/R-CFA-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Canis familiaris 30408 R-CFA-6799178 https://reactome.org/PathwayBrowser/#/R-CFA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Canis familiaris 30408 R-CFA-6799179 https://reactome.org/PathwayBrowser/#/R-CFA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Canis familiaris 30408 R-CFA-6799196 https://reactome.org/PathwayBrowser/#/R-CFA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Canis familiaris 30408 R-CFA-6799203 https://reactome.org/PathwayBrowser/#/R-CFA-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Canis familiaris 30408 R-CFA-6800868 https://reactome.org/PathwayBrowser/#/R-CFA-6800868 NDUF subunits bind to form the IP subcomplex IEA Canis familiaris 30408 R-CFA-73585 https://reactome.org/PathwayBrowser/#/R-CFA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Canis familiaris 30408 R-CFA-73616 https://reactome.org/PathwayBrowser/#/R-CFA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Canis familiaris 30408 R-CFA-74247 https://reactome.org/PathwayBrowser/#/R-CFA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Canis familiaris 30408 R-CFA-74258 https://reactome.org/PathwayBrowser/#/R-CFA-74258 XDH oxidizes xanthine to form urate IEA Canis familiaris 30408 R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 30408 R-CFA-9727349 https://reactome.org/PathwayBrowser/#/R-CFA-9727349 XDH dehydrogenates xanthine to form urate IEA Canis familiaris 30408 R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 30408 R-DDI-5690023 https://reactome.org/PathwayBrowser/#/R-DDI-5690023 NUBPL binds 4Fe-4S IEA Dictyostelium discoideum 30408 R-DDI-5690873 https://reactome.org/PathwayBrowser/#/R-DDI-5690873 ACO1 binds 4Fe-4S IEA Dictyostelium discoideum 30408 R-DDI-5690911 https://reactome.org/PathwayBrowser/#/R-DDI-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Dictyostelium discoideum 30408 R-DDI-6788523 https://reactome.org/PathwayBrowser/#/R-DDI-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Dictyostelium discoideum 30408 R-DDI-6788556 https://reactome.org/PathwayBrowser/#/R-DDI-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Dictyostelium discoideum 30408 R-DDI-6800868 https://reactome.org/PathwayBrowser/#/R-DDI-6800868 NDUF subunits bind to form the IP subcomplex IEA Dictyostelium discoideum 30408 R-DDI-73585 https://reactome.org/PathwayBrowser/#/R-DDI-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Dictyostelium discoideum 30408 R-DDI-73616 https://reactome.org/PathwayBrowser/#/R-DDI-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Dictyostelium discoideum 30408 R-DDI-74247 https://reactome.org/PathwayBrowser/#/R-DDI-74247 XDH oxidizes hypoxanthine to form xanthine IEA Dictyostelium discoideum 30408 R-DDI-74258 https://reactome.org/PathwayBrowser/#/R-DDI-74258 XDH oxidizes xanthine to form urate IEA Dictyostelium discoideum 30408 R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 30408 R-DDI-9727349 https://reactome.org/PathwayBrowser/#/R-DDI-9727349 XDH dehydrogenates xanthine to form urate IEA Dictyostelium discoideum 30408 R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 30408 R-DME-163217 https://reactome.org/PathwayBrowser/#/R-DME-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Drosophila melanogaster 30408 R-DME-5690023 https://reactome.org/PathwayBrowser/#/R-DME-5690023 NUBPL binds 4Fe-4S IEA Drosophila melanogaster 30408 R-DME-5690873 https://reactome.org/PathwayBrowser/#/R-DME-5690873 ACO1 binds 4Fe-4S IEA Drosophila melanogaster 30408 R-DME-5690911 https://reactome.org/PathwayBrowser/#/R-DME-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Drosophila melanogaster 30408 R-DME-6788523 https://reactome.org/PathwayBrowser/#/R-DME-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Drosophila melanogaster 30408 R-DME-6788556 https://reactome.org/PathwayBrowser/#/R-DME-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Drosophila melanogaster 30408 R-DME-6799178 https://reactome.org/PathwayBrowser/#/R-DME-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Drosophila melanogaster 30408 R-DME-6799191 https://reactome.org/PathwayBrowser/#/R-DME-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Drosophila melanogaster 30408 R-DME-6799196 https://reactome.org/PathwayBrowser/#/R-DME-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Drosophila melanogaster 30408 R-DME-6799197 https://reactome.org/PathwayBrowser/#/R-DME-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Drosophila melanogaster 30408 R-DME-6799202 https://reactome.org/PathwayBrowser/#/R-DME-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Drosophila melanogaster 30408 R-DME-6799203 https://reactome.org/PathwayBrowser/#/R-DME-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Drosophila melanogaster 30408 R-DME-6800868 https://reactome.org/PathwayBrowser/#/R-DME-6800868 NDUF subunits bind to form the IP subcomplex IEA Drosophila melanogaster 30408 R-DME-73585 https://reactome.org/PathwayBrowser/#/R-DME-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Drosophila melanogaster 30408 R-DME-73616 https://reactome.org/PathwayBrowser/#/R-DME-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Drosophila melanogaster 30408 R-DME-74247 https://reactome.org/PathwayBrowser/#/R-DME-74247 XDH oxidizes hypoxanthine to form xanthine IEA Drosophila melanogaster 30408 R-DME-74258 https://reactome.org/PathwayBrowser/#/R-DME-74258 XDH oxidizes xanthine to form urate IEA Drosophila melanogaster 30408 R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 30408 R-DME-9727349 https://reactome.org/PathwayBrowser/#/R-DME-9727349 XDH dehydrogenates xanthine to form urate IEA Drosophila melanogaster 30408 R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 30408 R-DRE-163217 https://reactome.org/PathwayBrowser/#/R-DRE-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Danio rerio 30408 R-DRE-5690023 https://reactome.org/PathwayBrowser/#/R-DRE-5690023 NUBPL binds 4Fe-4S IEA Danio rerio 30408 R-DRE-5690873 https://reactome.org/PathwayBrowser/#/R-DRE-5690873 ACO1 binds 4Fe-4S IEA Danio rerio 30408 R-DRE-5690911 https://reactome.org/PathwayBrowser/#/R-DRE-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Danio rerio 30408 R-DRE-6788523 https://reactome.org/PathwayBrowser/#/R-DRE-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Danio rerio 30408 R-DRE-6788556 https://reactome.org/PathwayBrowser/#/R-DRE-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Danio rerio 30408 R-DRE-6799197 https://reactome.org/PathwayBrowser/#/R-DRE-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Danio rerio 30408 R-DRE-73585 https://reactome.org/PathwayBrowser/#/R-DRE-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Danio rerio 30408 R-DRE-73616 https://reactome.org/PathwayBrowser/#/R-DRE-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Danio rerio 30408 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Gallus gallus 30408 R-GGA-5690023 https://reactome.org/PathwayBrowser/#/R-GGA-5690023 NUBPL binds 4Fe-4S IEA Gallus gallus 30408 R-GGA-5690873 https://reactome.org/PathwayBrowser/#/R-GGA-5690873 ACO1 binds 4Fe-4S IEA Gallus gallus 30408 R-GGA-5690911 https://reactome.org/PathwayBrowser/#/R-GGA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Gallus gallus 30408 R-GGA-6788523 https://reactome.org/PathwayBrowser/#/R-GGA-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Gallus gallus 30408 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus 30408 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus 30408 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus 30408 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus 30408 R-GGA-6799197 https://reactome.org/PathwayBrowser/#/R-GGA-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Gallus gallus 30408 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus 30408 R-GGA-6799203 https://reactome.org/PathwayBrowser/#/R-GGA-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Gallus gallus 30408 R-GGA-6800868 https://reactome.org/PathwayBrowser/#/R-GGA-6800868 NDUF subunits bind to form the IP subcomplex IEA Gallus gallus 30408 R-GGA-73585 https://reactome.org/PathwayBrowser/#/R-GGA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Gallus gallus 30408 R-GGA-73616 https://reactome.org/PathwayBrowser/#/R-GGA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Gallus gallus 30408 R-GGA-74247 https://reactome.org/PathwayBrowser/#/R-GGA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Gallus gallus 30408 R-GGA-74258 https://reactome.org/PathwayBrowser/#/R-GGA-74258 XDH oxidizes xanthine to form urate IEA Gallus gallus 30408 R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 30408 R-GGA-9727349 https://reactome.org/PathwayBrowser/#/R-GGA-9727349 XDH dehydrogenates xanthine to form urate IEA Gallus gallus 30408 R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 30408 R-HSA-163217 https://reactome.org/PathwayBrowser/#/R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 TAS Homo sapiens 30408 R-HSA-5690023 https://reactome.org/PathwayBrowser/#/R-HSA-5690023 NUBPL binds 4Fe-4S TAS Homo sapiens 30408 R-HSA-5690873 https://reactome.org/PathwayBrowser/#/R-HSA-5690873 ACO1 binds 4Fe-4S TAS Homo sapiens 30408 R-HSA-5690911 https://reactome.org/PathwayBrowser/#/R-HSA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT TAS Homo sapiens 30408 R-HSA-6788523 https://reactome.org/PathwayBrowser/#/R-HSA-6788523 NUBPL transfers 4Fe-4S to Complex I subunits TAS Homo sapiens 30408 R-HSA-6788556 https://reactome.org/PathwayBrowser/#/R-HSA-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 TAS Homo sapiens 30408 R-HSA-6799178 https://reactome.org/PathwayBrowser/#/R-HSA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 TAS Homo sapiens 30408 R-HSA-6799179 https://reactome.org/PathwayBrowser/#/R-HSA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex TAS Homo sapiens 30408 R-HSA-6799191 https://reactome.org/PathwayBrowser/#/R-HSA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex TAS Homo sapiens 30408 R-HSA-6799196 https://reactome.org/PathwayBrowser/#/R-HSA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I TAS Homo sapiens 30408 R-HSA-6799197 https://reactome.org/PathwayBrowser/#/R-HSA-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex TAS Homo sapiens 30408 R-HSA-6799202 https://reactome.org/PathwayBrowser/#/R-HSA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex TAS Homo sapiens 30408 R-HSA-6799203 https://reactome.org/PathwayBrowser/#/R-HSA-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 TAS Homo sapiens 30408 R-HSA-6800868 https://reactome.org/PathwayBrowser/#/R-HSA-6800868 NDUF subunits bind to form the IP subcomplex TAS Homo sapiens 30408 R-HSA-6800870 https://reactome.org/PathwayBrowser/#/R-HSA-6800870 NDUF subunits bind to form the FP subcomplex TAS Homo sapiens 30408 R-HSA-73585 https://reactome.org/PathwayBrowser/#/R-HSA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ TAS Homo sapiens 30408 R-HSA-73616 https://reactome.org/PathwayBrowser/#/R-HSA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ TAS Homo sapiens 30408 R-HSA-74247 https://reactome.org/PathwayBrowser/#/R-HSA-74247 XDH oxidizes hypoxanthine to form xanthine TAS Homo sapiens 30408 R-HSA-74258 https://reactome.org/PathwayBrowser/#/R-HSA-74258 XDH oxidizes xanthine to form urate TAS Homo sapiens 30408 R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 30408 R-HSA-9727349 https://reactome.org/PathwayBrowser/#/R-HSA-9727349 XDH dehydrogenates xanthine to form urate TAS Homo sapiens 30408 R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 30408 R-HSA-9854984 https://reactome.org/PathwayBrowser/#/R-HSA-9854984 Transfer of Fe-S clusters to SDHB TAS Homo sapiens 30408 R-HSA-9855212 https://reactome.org/PathwayBrowser/#/R-HSA-9855212 SDHA binds to SDHB TAS Homo sapiens 30408 R-HSA-9855252 https://reactome.org/PathwayBrowser/#/R-HSA-9855252 SDHA:SDHB binds to SDHC:SDHD TAS Homo sapiens 30408 R-MMU-163217 https://reactome.org/PathwayBrowser/#/R-MMU-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Mus musculus 30408 R-MMU-5690023 https://reactome.org/PathwayBrowser/#/R-MMU-5690023 NUBPL binds 4Fe-4S IEA Mus musculus 30408 R-MMU-5690873 https://reactome.org/PathwayBrowser/#/R-MMU-5690873 ACO1 binds 4Fe-4S IEA Mus musculus 30408 R-MMU-5690911 https://reactome.org/PathwayBrowser/#/R-MMU-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Mus musculus 30408 R-MMU-6788523 https://reactome.org/PathwayBrowser/#/R-MMU-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Mus musculus 30408 R-MMU-6788556 https://reactome.org/PathwayBrowser/#/R-MMU-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Mus musculus 30408 R-MMU-6799178 https://reactome.org/PathwayBrowser/#/R-MMU-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Mus musculus 30408 R-MMU-6799179 https://reactome.org/PathwayBrowser/#/R-MMU-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Mus musculus 30408 R-MMU-6799191 https://reactome.org/PathwayBrowser/#/R-MMU-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Mus musculus 30408 R-MMU-6799196 https://reactome.org/PathwayBrowser/#/R-MMU-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Mus musculus 30408 R-MMU-6799197 https://reactome.org/PathwayBrowser/#/R-MMU-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Mus musculus 30408 R-MMU-6799202 https://reactome.org/PathwayBrowser/#/R-MMU-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Mus musculus 30408 R-MMU-6799203 https://reactome.org/PathwayBrowser/#/R-MMU-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Mus musculus 30408 R-MMU-6800868 https://reactome.org/PathwayBrowser/#/R-MMU-6800868 NDUF subunits bind to form the IP subcomplex IEA Mus musculus 30408 R-MMU-6800870 https://reactome.org/PathwayBrowser/#/R-MMU-6800870 NDUF subunits bind to form the FP subcomplex IEA Mus musculus 30408 R-MMU-73585 https://reactome.org/PathwayBrowser/#/R-MMU-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Mus musculus 30408 R-MMU-73616 https://reactome.org/PathwayBrowser/#/R-MMU-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Mus musculus 30408 R-MMU-74247 https://reactome.org/PathwayBrowser/#/R-MMU-74247 XDH oxidizes hypoxanthine to form xanthine IEA Mus musculus 30408 R-MMU-74258 https://reactome.org/PathwayBrowser/#/R-MMU-74258 XDH oxidizes xanthine to form urate IEA Mus musculus 30408 R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 30408 R-MMU-9727349 https://reactome.org/PathwayBrowser/#/R-MMU-9727349 XDH dehydrogenates xanthine to form urate IEA Mus musculus 30408 R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 30408 R-MMU-9854984 https://reactome.org/PathwayBrowser/#/R-MMU-9854984 Transfer of Fe-S clusters to SDHB IEA Mus musculus 30408 R-MMU-9855212 https://reactome.org/PathwayBrowser/#/R-MMU-9855212 SDHA binds to SDHB IEA Mus musculus 30408 R-MMU-9855252 https://reactome.org/PathwayBrowser/#/R-MMU-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Mus musculus 30408 R-MTU-936655 https://reactome.org/PathwayBrowser/#/R-MTU-936655 sulfite results from reduction of APS TAS Mycobacterium tuberculosis 30408 R-MTU-936703 https://reactome.org/PathwayBrowser/#/R-MTU-936703 sulfite is reduced to sulfide TAS Mycobacterium tuberculosis 30408 R-PFA-5690873 https://reactome.org/PathwayBrowser/#/R-PFA-5690873 ACO1 binds 4Fe-4S IEA Plasmodium falciparum 30408 R-PFA-5690911 https://reactome.org/PathwayBrowser/#/R-PFA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Plasmodium falciparum 30408 R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Rattus norvegicus 30408 R-RNO-5690023 https://reactome.org/PathwayBrowser/#/R-RNO-5690023 NUBPL binds 4Fe-4S IEA Rattus norvegicus 30408 R-RNO-5690873 https://reactome.org/PathwayBrowser/#/R-RNO-5690873 ACO1 binds 4Fe-4S IEA Rattus norvegicus 30408 R-RNO-5690911 https://reactome.org/PathwayBrowser/#/R-RNO-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Rattus norvegicus 30408 R-RNO-6788523 https://reactome.org/PathwayBrowser/#/R-RNO-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Rattus norvegicus 30408 R-RNO-6788556 https://reactome.org/PathwayBrowser/#/R-RNO-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Rattus norvegicus 30408 R-RNO-6799178 https://reactome.org/PathwayBrowser/#/R-RNO-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Rattus norvegicus 30408 R-RNO-6799179 https://reactome.org/PathwayBrowser/#/R-RNO-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Rattus norvegicus 30408 R-RNO-6799191 https://reactome.org/PathwayBrowser/#/R-RNO-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Rattus norvegicus 30408 R-RNO-6799196 https://reactome.org/PathwayBrowser/#/R-RNO-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Rattus norvegicus 30408 R-RNO-6799197 https://reactome.org/PathwayBrowser/#/R-RNO-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Rattus norvegicus 30408 R-RNO-6799202 https://reactome.org/PathwayBrowser/#/R-RNO-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Rattus norvegicus 30408 R-RNO-6799203 https://reactome.org/PathwayBrowser/#/R-RNO-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Rattus norvegicus 30408 R-RNO-6800868 https://reactome.org/PathwayBrowser/#/R-RNO-6800868 NDUF subunits bind to form the IP subcomplex IEA Rattus norvegicus 30408 R-RNO-6800870 https://reactome.org/PathwayBrowser/#/R-RNO-6800870 NDUF subunits bind to form the FP subcomplex IEA Rattus norvegicus 30408 R-RNO-73585 https://reactome.org/PathwayBrowser/#/R-RNO-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Rattus norvegicus 30408 R-RNO-73616 https://reactome.org/PathwayBrowser/#/R-RNO-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Rattus norvegicus 30408 R-RNO-74247 https://reactome.org/PathwayBrowser/#/R-RNO-74247 XDH oxidizes hypoxanthine to form xanthine IEA Rattus norvegicus 30408 R-RNO-74258 https://reactome.org/PathwayBrowser/#/R-RNO-74258 XDH oxidizes xanthine to form urate IEA Rattus norvegicus 30408 R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 30408 R-RNO-9727349 https://reactome.org/PathwayBrowser/#/R-RNO-9727349 XDH dehydrogenates xanthine to form urate IEA Rattus norvegicus 30408 R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 30408 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Sus scrofa 30408 R-SSC-5690023 https://reactome.org/PathwayBrowser/#/R-SSC-5690023 NUBPL binds 4Fe-4S IEA Sus scrofa 30408 R-SSC-5690873 https://reactome.org/PathwayBrowser/#/R-SSC-5690873 ACO1 binds 4Fe-4S IEA Sus scrofa 30408 R-SSC-5690911 https://reactome.org/PathwayBrowser/#/R-SSC-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Sus scrofa 30408 R-SSC-6788523 https://reactome.org/PathwayBrowser/#/R-SSC-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Sus scrofa 30408 R-SSC-6788556 https://reactome.org/PathwayBrowser/#/R-SSC-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Sus scrofa 30408 R-SSC-6799178 https://reactome.org/PathwayBrowser/#/R-SSC-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Sus scrofa 30408 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa 30408 R-SSC-6799191 https://reactome.org/PathwayBrowser/#/R-SSC-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Sus scrofa 30408 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa 30408 R-SSC-6799197 https://reactome.org/PathwayBrowser/#/R-SSC-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Sus scrofa 30408 R-SSC-6799202 https://reactome.org/PathwayBrowser/#/R-SSC-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Sus scrofa 30408 R-SSC-6799203 https://reactome.org/PathwayBrowser/#/R-SSC-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Sus scrofa 30408 R-SSC-6800868 https://reactome.org/PathwayBrowser/#/R-SSC-6800868 NDUF subunits bind to form the IP subcomplex IEA Sus scrofa 30408 R-SSC-73585 https://reactome.org/PathwayBrowser/#/R-SSC-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Sus scrofa 30408 R-SSC-73616 https://reactome.org/PathwayBrowser/#/R-SSC-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Sus scrofa 30408 R-SSC-74247 https://reactome.org/PathwayBrowser/#/R-SSC-74247 XDH oxidizes hypoxanthine to form xanthine IEA Sus scrofa 30408 R-SSC-74258 https://reactome.org/PathwayBrowser/#/R-SSC-74258 XDH oxidizes xanthine to form urate IEA Sus scrofa 30408 R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 30408 R-SSC-9727349 https://reactome.org/PathwayBrowser/#/R-SSC-9727349 XDH dehydrogenates xanthine to form urate IEA Sus scrofa 30408 R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 30408 R-SSC-9854984 https://reactome.org/PathwayBrowser/#/R-SSC-9854984 Transfer of Fe-S clusters to SDHB IEA Sus scrofa 30408 R-SSC-9855212 https://reactome.org/PathwayBrowser/#/R-SSC-9855212 SDHA binds to SDHB IEA Sus scrofa 30408 R-SSC-9855252 https://reactome.org/PathwayBrowser/#/R-SSC-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Sus scrofa 30408 R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Xenopus tropicalis 30408 R-XTR-5690023 https://reactome.org/PathwayBrowser/#/R-XTR-5690023 NUBPL binds 4Fe-4S IEA Xenopus tropicalis 30408 R-XTR-5690873 https://reactome.org/PathwayBrowser/#/R-XTR-5690873 ACO1 binds 4Fe-4S IEA Xenopus tropicalis 30408 R-XTR-5690911 https://reactome.org/PathwayBrowser/#/R-XTR-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Xenopus tropicalis 30408 R-XTR-6788523 https://reactome.org/PathwayBrowser/#/R-XTR-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Xenopus tropicalis 30408 R-XTR-6788556 https://reactome.org/PathwayBrowser/#/R-XTR-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Xenopus tropicalis 30408 R-XTR-6799197 https://reactome.org/PathwayBrowser/#/R-XTR-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Xenopus tropicalis 30408 R-XTR-6799202 https://reactome.org/PathwayBrowser/#/R-XTR-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Xenopus tropicalis 30408 R-XTR-6799203 https://reactome.org/PathwayBrowser/#/R-XTR-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Xenopus tropicalis 30408 R-XTR-6800868 https://reactome.org/PathwayBrowser/#/R-XTR-6800868 NDUF subunits bind to form the IP subcomplex IEA Xenopus tropicalis 30408 R-XTR-73585 https://reactome.org/PathwayBrowser/#/R-XTR-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Xenopus tropicalis 30408 R-XTR-73616 https://reactome.org/PathwayBrowser/#/R-XTR-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Xenopus tropicalis 30408 R-XTR-74247 https://reactome.org/PathwayBrowser/#/R-XTR-74247 XDH oxidizes hypoxanthine to form xanthine IEA Xenopus tropicalis 30408 R-XTR-74258 https://reactome.org/PathwayBrowser/#/R-XTR-74258 XDH oxidizes xanthine to form urate IEA Xenopus tropicalis 30408 R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 30408 R-XTR-9727349 https://reactome.org/PathwayBrowser/#/R-XTR-9727349 XDH dehydrogenates xanthine to form urate IEA Xenopus tropicalis 30408 R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 30408 R-XTR-9855212 https://reactome.org/PathwayBrowser/#/R-XTR-9855212 SDHA binds to SDHB IEA Xenopus tropicalis 30408 R-XTR-9855252 https://reactome.org/PathwayBrowser/#/R-XTR-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Xenopus tropicalis 30563 R-BTA-1306876 https://reactome.org/PathwayBrowser/#/R-BTA-1306876 NLRP3 activation by small molecules IEA Bos taurus 30563 R-CFA-1306876 https://reactome.org/PathwayBrowser/#/R-CFA-1306876 NLRP3 activation by small molecules IEA Canis familiaris 30563 R-DRE-1306876 https://reactome.org/PathwayBrowser/#/R-DRE-1306876 NLRP3 activation by small molecules IEA Danio rerio 30563 R-GGA-1306876 https://reactome.org/PathwayBrowser/#/R-GGA-1306876 NLRP3 activation by small molecules IEA Gallus gallus 30563 R-HSA-1296421 https://reactome.org/PathwayBrowser/#/R-HSA-1296421 NLRP3 oligomerizes via NACHT domains TAS Homo sapiens 30563 R-HSA-1306876 https://reactome.org/PathwayBrowser/#/R-HSA-1306876 NLRP3 activation by small molecules TAS Homo sapiens 30563 R-HSA-844610 https://reactome.org/PathwayBrowser/#/R-HSA-844610 NLRP3 recruits PYCARD (ASC) via a PYD-PYD interaction TAS Homo sapiens 30563 R-HSA-844612 https://reactome.org/PathwayBrowser/#/R-HSA-844612 PYCARD recruits procaspase-1 via CARD TAS Homo sapiens 30563 R-MMU-1306876 https://reactome.org/PathwayBrowser/#/R-MMU-1306876 NLRP3 activation by small molecules IEA Mus musculus 30563 R-RNO-1306876 https://reactome.org/PathwayBrowser/#/R-RNO-1306876 NLRP3 activation by small molecules IEA Rattus norvegicus 30563 R-SSC-1306876 https://reactome.org/PathwayBrowser/#/R-SSC-1306876 NLRP3 activation by small molecules IEA Sus scrofa 30563 R-XTR-1306876 https://reactome.org/PathwayBrowser/#/R-XTR-1306876 NLRP3 activation by small molecules IEA Xenopus tropicalis 30614 R-BTA-176054 https://reactome.org/PathwayBrowser/#/R-BTA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Bos taurus 30614 R-CEL-176054 https://reactome.org/PathwayBrowser/#/R-CEL-176054 GST dimers conjugate GSH with cytosolic substrates IEA Caenorhabditis elegans 30614 R-CFA-176054 https://reactome.org/PathwayBrowser/#/R-CFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Canis familiaris 30614 R-DDI-176054 https://reactome.org/PathwayBrowser/#/R-DDI-176054 GST dimers conjugate GSH with cytosolic substrates IEA Dictyostelium discoideum 30614 R-DME-176054 https://reactome.org/PathwayBrowser/#/R-DME-176054 GST dimers conjugate GSH with cytosolic substrates IEA Drosophila melanogaster 30614 R-DRE-176054 https://reactome.org/PathwayBrowser/#/R-DRE-176054 GST dimers conjugate GSH with cytosolic substrates IEA Danio rerio 30614 R-GGA-176054 https://reactome.org/PathwayBrowser/#/R-GGA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Gallus gallus 30614 R-HSA-176054 https://reactome.org/PathwayBrowser/#/R-HSA-176054 GST dimers conjugate GSH with cytosolic substrates TAS Homo sapiens 30614 R-MMU-176054 https://reactome.org/PathwayBrowser/#/R-MMU-176054 GST dimers conjugate GSH with cytosolic substrates IEA Mus musculus 30614 R-PFA-176054 https://reactome.org/PathwayBrowser/#/R-PFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Plasmodium falciparum 30614 R-RNO-176054 https://reactome.org/PathwayBrowser/#/R-RNO-176054 GST dimers conjugate GSH with cytosolic substrates IEA Rattus norvegicus 30614 R-SSC-176054 https://reactome.org/PathwayBrowser/#/R-SSC-176054 GST dimers conjugate GSH with cytosolic substrates IEA Sus scrofa 30614 R-XTR-176054 https://reactome.org/PathwayBrowser/#/R-XTR-176054 GST dimers conjugate GSH with cytosolic substrates IEA Xenopus tropicalis 30616 R-BTA-109624 https://reactome.org/PathwayBrowser/#/R-BTA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Bos taurus 30616 R-BTA-109671 https://reactome.org/PathwayBrowser/#/R-BTA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Bos taurus 30616 R-BTA-109699 https://reactome.org/PathwayBrowser/#/R-BTA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-109702 https://reactome.org/PathwayBrowser/#/R-BTA-109702 PDPK1 phosphorylates AKT2 IEA Bos taurus 30616 R-BTA-109759 https://reactome.org/PathwayBrowser/#/R-BTA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Bos taurus 30616 R-BTA-109822 https://reactome.org/PathwayBrowser/#/R-BTA-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Bos taurus 30616 R-BTA-109823 https://reactome.org/PathwayBrowser/#/R-BTA-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Bos taurus 30616 R-BTA-109860 https://reactome.org/PathwayBrowser/#/R-BTA-109860 MAP2K1 phosphorylates MAPK3 IEA Bos taurus 30616 R-BTA-109862 https://reactome.org/PathwayBrowser/#/R-BTA-109862 MAP2K2 phosphorylates MAPK1 IEA Bos taurus 30616 R-BTA-109903 https://reactome.org/PathwayBrowser/#/R-BTA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Bos taurus 30616 R-BTA-110133 https://reactome.org/PathwayBrowser/#/R-BTA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Bos taurus 30616 R-BTA-110137 https://reactome.org/PathwayBrowser/#/R-BTA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Bos taurus 30616 R-BTA-110138 https://reactome.org/PathwayBrowser/#/R-BTA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 30616 R-BTA-110141 https://reactome.org/PathwayBrowser/#/R-BTA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Bos taurus 30616 R-BTA-110144 https://reactome.org/PathwayBrowser/#/R-BTA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Bos taurus 30616 R-BTA-110145 https://reactome.org/PathwayBrowser/#/R-BTA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Bos taurus 30616 R-BTA-1112510 https://reactome.org/PathwayBrowser/#/R-BTA-1112510 IL6ST is tyrosine phosphorylated IEA Bos taurus 30616 R-BTA-1112514 https://reactome.org/PathwayBrowser/#/R-BTA-1112514 JAK activation IEA Bos taurus 30616 R-BTA-1112602 https://reactome.org/PathwayBrowser/#/R-BTA-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Bos taurus 30616 R-BTA-1112703 https://reactome.org/PathwayBrowser/#/R-BTA-1112703 PTPN11 is phosphorylated IEA Bos taurus 30616 R-BTA-1112727 https://reactome.org/PathwayBrowser/#/R-BTA-1112727 Serine phosphorylation of STATs IEA Bos taurus 30616 R-BTA-111742 https://reactome.org/PathwayBrowser/#/R-BTA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 30616 R-BTA-111751 https://reactome.org/PathwayBrowser/#/R-BTA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 30616 R-BTA-111804 https://reactome.org/PathwayBrowser/#/R-BTA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 30616 R-BTA-111898 https://reactome.org/PathwayBrowser/#/R-BTA-111898 Phosphorylation of cPLA2 by ERK-2 IEA Bos taurus 30616 R-BTA-111915 https://reactome.org/PathwayBrowser/#/R-BTA-111915 CAMK4 autophosphorylates IEA Bos taurus 30616 R-BTA-111930 https://reactome.org/PathwayBrowser/#/R-BTA-111930 Adenylate cyclase produces cAMP IEA Bos taurus 30616 R-BTA-111970 https://reactome.org/PathwayBrowser/#/R-BTA-111970 PKC phosphorylates GRK2 IEA Bos taurus 30616 R-BTA-112342 https://reactome.org/PathwayBrowser/#/R-BTA-112342 Inactivation of MAP2K1 by CDK1 IEA Bos taurus 30616 R-BTA-112381 https://reactome.org/PathwayBrowser/#/R-BTA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Bos taurus 30616 R-BTA-114252 https://reactome.org/PathwayBrowser/#/R-BTA-114252 Cleavage of Procaspase-3 by the apoptosome IEA Bos taurus 30616 R-BTA-114254 https://reactome.org/PathwayBrowser/#/R-BTA-114254 CYCS binds to APAF1 IEA Bos taurus 30616 R-BTA-114256 https://reactome.org/PathwayBrowser/#/R-BTA-114256 CYCS:APAF1 binds procaspase-9 IEA Bos taurus 30616 R-BTA-114261 https://reactome.org/PathwayBrowser/#/R-BTA-114261 Cleavage of Procaspase-7 by the apoptosome IEA Bos taurus 30616 R-BTA-114600 https://reactome.org/PathwayBrowser/#/R-BTA-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Bos taurus 30616 R-BTA-114683 https://reactome.org/PathwayBrowser/#/R-BTA-114683 Phosphorylation of Platelet Sec-1 IEA Bos taurus 30616 R-BTA-114684 https://reactome.org/PathwayBrowser/#/R-BTA-114684 Phosphorylation of Syntaxin-4 IEA Bos taurus 30616 R-BTA-1168459 https://reactome.org/PathwayBrowser/#/R-BTA-1168459 Lyn activates ERK IEA Bos taurus 30616 R-BTA-1168635 https://reactome.org/PathwayBrowser/#/R-BTA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Bos taurus 30616 R-BTA-1168638 https://reactome.org/PathwayBrowser/#/R-BTA-1168638 Activated IKK phosphorylates I-kappaB IEA Bos taurus 30616 R-BTA-1169394 https://reactome.org/PathwayBrowser/#/R-BTA-1169394 ISGylation of IRF3 IEA Bos taurus 30616 R-BTA-1169397 https://reactome.org/PathwayBrowser/#/R-BTA-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Bos taurus 30616 R-BTA-1169398 https://reactome.org/PathwayBrowser/#/R-BTA-1169398 ISGylation of host protein filamin B IEA Bos taurus 30616 R-BTA-1169402 https://reactome.org/PathwayBrowser/#/R-BTA-1169402 ISGylation of E2 conjugating enzymes IEA Bos taurus 30616 R-BTA-1169405 https://reactome.org/PathwayBrowser/#/R-BTA-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Bos taurus 30616 R-BTA-1169406 https://reactome.org/PathwayBrowser/#/R-BTA-1169406 ISGylation of host proteins IEA Bos taurus 30616 R-BTA-1181149 https://reactome.org/PathwayBrowser/#/R-BTA-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Bos taurus 30616 R-BTA-1226094 https://reactome.org/PathwayBrowser/#/R-BTA-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Bos taurus 30616 R-BTA-1226095 https://reactome.org/PathwayBrowser/#/R-BTA-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Bos taurus 30616 R-BTA-1247935 https://reactome.org/PathwayBrowser/#/R-BTA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Bos taurus 30616 R-BTA-1247960 https://reactome.org/PathwayBrowser/#/R-BTA-1247960 Activation of p38 MAPK IEA Bos taurus 30616 R-BTA-1250195 https://reactome.org/PathwayBrowser/#/R-BTA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Bos taurus 30616 R-BTA-1250315 https://reactome.org/PathwayBrowser/#/R-BTA-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Bos taurus 30616 R-BTA-1250348 https://reactome.org/PathwayBrowser/#/R-BTA-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Bos taurus 30616 R-BTA-1250370 https://reactome.org/PathwayBrowser/#/R-BTA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Bos taurus 30616 R-BTA-1250462 https://reactome.org/PathwayBrowser/#/R-BTA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Bos taurus 30616 R-BTA-1295540 https://reactome.org/PathwayBrowser/#/R-BTA-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Bos taurus 30616 R-BTA-1295609 https://reactome.org/PathwayBrowser/#/R-BTA-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Bos taurus 30616 R-BTA-1296024 https://reactome.org/PathwayBrowser/#/R-BTA-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Bos taurus 30616 R-BTA-1306957 https://reactome.org/PathwayBrowser/#/R-BTA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Bos taurus 30616 R-BTA-1306979 https://reactome.org/PathwayBrowser/#/R-BTA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Bos taurus 30616 R-BTA-1307963 https://reactome.org/PathwayBrowser/#/R-BTA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Bos taurus 30616 R-BTA-1362270 https://reactome.org/PathwayBrowser/#/R-BTA-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Bos taurus 30616 R-BTA-1369065 https://reactome.org/PathwayBrowser/#/R-BTA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Bos taurus 30616 R-BTA-139855 https://reactome.org/PathwayBrowser/#/R-BTA-139855 P2X1-mediated entry of Ca++ from plasma IEA Bos taurus 30616 R-BTA-139908 https://reactome.org/PathwayBrowser/#/R-BTA-139908 Phosphorylation of DLC2 by MAPK8 IEA Bos taurus 30616 R-BTA-139918 https://reactome.org/PathwayBrowser/#/R-BTA-139918 Phosphorylation of BIM by JNK IEA Bos taurus 30616 R-BTA-1433418 https://reactome.org/PathwayBrowser/#/R-BTA-1433418 Phosphorylation of JAK2 IEA Bos taurus 30616 R-BTA-1433454 https://reactome.org/PathwayBrowser/#/R-BTA-1433454 Phosphorylation of GAB2 by SFKs IEA Bos taurus 30616 R-BTA-1433488 https://reactome.org/PathwayBrowser/#/R-BTA-1433488 Phosphorylation of SHP2 by SFKs IEA Bos taurus 30616 R-BTA-1433506 https://reactome.org/PathwayBrowser/#/R-BTA-1433506 Phosphorylation of APS IEA Bos taurus 30616 R-BTA-1433514 https://reactome.org/PathwayBrowser/#/R-BTA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Bos taurus 30616 R-BTA-1433542 https://reactome.org/PathwayBrowser/#/R-BTA-1433542 Phosphorylation and activation of VAV1 IEA Bos taurus 30616 R-BTA-1454916 https://reactome.org/PathwayBrowser/#/R-BTA-1454916 The ABCC family mediates organic anion transport IEA Bos taurus 30616 R-BTA-1454928 https://reactome.org/PathwayBrowser/#/R-BTA-1454928 ABCG4 may mediate cholesterol efflux IEA Bos taurus 30616 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-1467466 https://reactome.org/PathwayBrowser/#/R-BTA-1467466 ABCA4 mediates atRAL transport IEA Bos taurus 30616 R-BTA-1470009 https://reactome.org/PathwayBrowser/#/R-BTA-1470009 Phosphorylation of STATs IEA Bos taurus 30616 R-BTA-1472121 https://reactome.org/PathwayBrowser/#/R-BTA-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Bos taurus 30616 R-BTA-1475422 https://reactome.org/PathwayBrowser/#/R-BTA-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Bos taurus 30616 R-BTA-1483004 https://reactome.org/PathwayBrowser/#/R-BTA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Bos taurus 30616 R-BTA-1483222 https://reactome.org/PathwayBrowser/#/R-BTA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Bos taurus 30616 R-BTA-1497853 https://reactome.org/PathwayBrowser/#/R-BTA-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Bos taurus 30616 R-BTA-1524186 https://reactome.org/PathwayBrowser/#/R-BTA-1524186 Phosphorylation of PLCgamma by PDGFR IEA Bos taurus 30616 R-BTA-1549526 https://reactome.org/PathwayBrowser/#/R-BTA-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Bos taurus 30616 R-BTA-156673 https://reactome.org/PathwayBrowser/#/R-BTA-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Bos taurus 30616 R-BTA-156678 https://reactome.org/PathwayBrowser/#/R-BTA-156678 Activation of Cdc25C IEA Bos taurus 30616 R-BTA-156682 https://reactome.org/PathwayBrowser/#/R-BTA-156682 PLK1 phosphorylates NUDC IEA Bos taurus 30616 R-BTA-156699 https://reactome.org/PathwayBrowser/#/R-BTA-156699 Inactivation of Wee1 kinase IEA Bos taurus 30616 R-BTA-156723 https://reactome.org/PathwayBrowser/#/R-BTA-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Bos taurus 30616 R-BTA-159101 https://reactome.org/PathwayBrowser/#/R-BTA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Bos taurus 30616 R-BTA-159425 https://reactome.org/PathwayBrowser/#/R-BTA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 30616 R-BTA-159443 https://reactome.org/PathwayBrowser/#/R-BTA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Bos taurus 30616 R-BTA-159567 https://reactome.org/PathwayBrowser/#/R-BTA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Bos taurus 30616 R-BTA-162657 https://reactome.org/PathwayBrowser/#/R-BTA-162657 Inactivation of Myt1 kinase IEA Bos taurus 30616 R-BTA-163010 https://reactome.org/PathwayBrowser/#/R-BTA-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Bos taurus 30616 R-BTA-163120 https://reactome.org/PathwayBrowser/#/R-BTA-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Bos taurus 30616 R-BTA-163215 https://reactome.org/PathwayBrowser/#/R-BTA-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Bos taurus 30616 R-BTA-1632857 https://reactome.org/PathwayBrowser/#/R-BTA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Bos taurus 30616 R-BTA-1638803 https://reactome.org/PathwayBrowser/#/R-BTA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Bos taurus 30616 R-BTA-1638845 https://reactome.org/PathwayBrowser/#/R-BTA-1638845 CERK phosphorylates CERA to form C1P IEA Bos taurus 30616 R-BTA-164832 https://reactome.org/PathwayBrowser/#/R-BTA-164832 ATPase synthesizes ATP IEA Bos taurus 30616 R-BTA-164834 https://reactome.org/PathwayBrowser/#/R-BTA-164834 Enzyme-bound ATP is released IEA Bos taurus 30616 R-BTA-165162 https://reactome.org/PathwayBrowser/#/R-BTA-165162 Phosphorylation of TSC2 by PKB IEA Bos taurus 30616 R-BTA-165182 https://reactome.org/PathwayBrowser/#/R-BTA-165182 Phosphorylation of complexed TSC2 by PKB IEA Bos taurus 30616 R-BTA-165692 https://reactome.org/PathwayBrowser/#/R-BTA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Bos taurus 30616 R-BTA-165718 https://reactome.org/PathwayBrowser/#/R-BTA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Bos taurus 30616 R-BTA-165726 https://reactome.org/PathwayBrowser/#/R-BTA-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Bos taurus 30616 R-BTA-165758 https://reactome.org/PathwayBrowser/#/R-BTA-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Bos taurus 30616 R-BTA-165766 https://reactome.org/PathwayBrowser/#/R-BTA-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Bos taurus 30616 R-BTA-165777 https://reactome.org/PathwayBrowser/#/R-BTA-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Bos taurus 30616 R-BTA-166245 https://reactome.org/PathwayBrowser/#/R-BTA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Bos taurus 30616 R-BTA-1675773 https://reactome.org/PathwayBrowser/#/R-BTA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Bos taurus 30616 R-BTA-1675776 https://reactome.org/PathwayBrowser/#/R-BTA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Bos taurus 30616 R-BTA-1675780 https://reactome.org/PathwayBrowser/#/R-BTA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Bos taurus 30616 R-BTA-1675810 https://reactome.org/PathwayBrowser/#/R-BTA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Bos taurus 30616 R-BTA-1675813 https://reactome.org/PathwayBrowser/#/R-BTA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Bos taurus 30616 R-BTA-1675883 https://reactome.org/PathwayBrowser/#/R-BTA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Bos taurus 30616 R-BTA-1675928 https://reactome.org/PathwayBrowser/#/R-BTA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Bos taurus 30616 R-BTA-1675939 https://reactome.org/PathwayBrowser/#/R-BTA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Bos taurus 30616 R-BTA-1675961 https://reactome.org/PathwayBrowser/#/R-BTA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Bos taurus 30616 R-BTA-1675974 https://reactome.org/PathwayBrowser/#/R-BTA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Bos taurus 30616 R-BTA-1676024 https://reactome.org/PathwayBrowser/#/R-BTA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Bos taurus 30616 R-BTA-1676048 https://reactome.org/PathwayBrowser/#/R-BTA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Bos taurus 30616 R-BTA-1676082 https://reactome.org/PathwayBrowser/#/R-BTA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Bos taurus 30616 R-BTA-1676109 https://reactome.org/PathwayBrowser/#/R-BTA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Bos taurus 30616 R-BTA-1676134 https://reactome.org/PathwayBrowser/#/R-BTA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Bos taurus 30616 R-BTA-1676145 https://reactome.org/PathwayBrowser/#/R-BTA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Bos taurus 30616 R-BTA-1676185 https://reactome.org/PathwayBrowser/#/R-BTA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Bos taurus 30616 R-BTA-1676206 https://reactome.org/PathwayBrowser/#/R-BTA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Bos taurus 30616 R-BTA-1678923 https://reactome.org/PathwayBrowser/#/R-BTA-1678923 TLR folding by chaperones GP96 and CNPY3 IEA Bos taurus 30616 R-BTA-1678944 https://reactome.org/PathwayBrowser/#/R-BTA-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Bos taurus 30616 R-BTA-168136 https://reactome.org/PathwayBrowser/#/R-BTA-168136 Activated JNKs phosphorylate c-JUN IEA Bos taurus 30616 R-BTA-168140 https://reactome.org/PathwayBrowser/#/R-BTA-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Bos taurus 30616 R-BTA-168162 https://reactome.org/PathwayBrowser/#/R-BTA-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Bos taurus 30616 R-BTA-169905 https://reactome.org/PathwayBrowser/#/R-BTA-169905 ARMS is phosphorylated by active TrkA receptor IEA Bos taurus 30616 R-BTA-170026 https://reactome.org/PathwayBrowser/#/R-BTA-170026 Protons are translocated from the intermembrane space to the matrix IEA Bos taurus 30616 R-BTA-170055 https://reactome.org/PathwayBrowser/#/R-BTA-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Bos taurus 30616 R-BTA-170070 https://reactome.org/PathwayBrowser/#/R-BTA-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Bos taurus 30616 R-BTA-170076 https://reactome.org/PathwayBrowser/#/R-BTA-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Bos taurus 30616 R-BTA-170087 https://reactome.org/PathwayBrowser/#/R-BTA-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Bos taurus 30616 R-BTA-170126 https://reactome.org/PathwayBrowser/#/R-BTA-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Bos taurus 30616 R-BTA-170676 https://reactome.org/PathwayBrowser/#/R-BTA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Bos taurus 30616 R-BTA-170843 https://reactome.org/PathwayBrowser/#/R-BTA-170843 TGFBR2 phosphorylates TGFBR1 IEA Bos taurus 30616 R-BTA-170868 https://reactome.org/PathwayBrowser/#/R-BTA-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Bos taurus 30616 R-BTA-170977 https://reactome.org/PathwayBrowser/#/R-BTA-170977 FRS2 is phosphorylated by active TrkA receptor IEA Bos taurus 30616 R-BTA-174079 https://reactome.org/PathwayBrowser/#/R-BTA-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Bos taurus 30616 R-BTA-174122 https://reactome.org/PathwayBrowser/#/R-BTA-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Bos taurus 30616 R-BTA-174164 https://reactome.org/PathwayBrowser/#/R-BTA-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Bos taurus 30616 R-BTA-174174 https://reactome.org/PathwayBrowser/#/R-BTA-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Bos taurus 30616 R-BTA-174251 https://reactome.org/PathwayBrowser/#/R-BTA-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Bos taurus 30616 R-BTA-174367 https://reactome.org/PathwayBrowser/#/R-BTA-174367 GCL ligates L-Glu to L-Cys IEA Bos taurus 30616 R-BTA-174389 https://reactome.org/PathwayBrowser/#/R-BTA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Bos taurus 30616 R-BTA-174391 https://reactome.org/PathwayBrowser/#/R-BTA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Bos taurus 30616 R-BTA-174392 https://reactome.org/PathwayBrowser/#/R-BTA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Bos taurus 30616 R-BTA-174394 https://reactome.org/PathwayBrowser/#/R-BTA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Bos taurus 30616 R-BTA-174438 https://reactome.org/PathwayBrowser/#/R-BTA-174438 Formation of the Flap Intermediate on the C-strand IEA Bos taurus 30616 R-BTA-174439 https://reactome.org/PathwayBrowser/#/R-BTA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Bos taurus 30616 R-BTA-176298 https://reactome.org/PathwayBrowser/#/R-BTA-176298 Activation of claspin IEA Bos taurus 30616 R-BTA-177157 https://reactome.org/PathwayBrowser/#/R-BTA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Bos taurus 30616 R-BTA-177275 https://reactome.org/PathwayBrowser/#/R-BTA-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Bos taurus 30616 R-BTA-177284 https://reactome.org/PathwayBrowser/#/R-BTA-177284 PKA phosphorylates PDE4B IEA Bos taurus 30616 R-BTA-177930 https://reactome.org/PathwayBrowser/#/R-BTA-177930 GAB1 phosphorylation by EGFR kinase IEA Bos taurus 30616 R-BTA-177933 https://reactome.org/PathwayBrowser/#/R-BTA-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Bos taurus 30616 R-BTA-177934 https://reactome.org/PathwayBrowser/#/R-BTA-177934 EGFR autophosphorylation IEA Bos taurus 30616 R-BTA-177937 https://reactome.org/PathwayBrowser/#/R-BTA-177937 Phosphorylation of EGFR by SRC kinase IEA Bos taurus 30616 R-BTA-177939 https://reactome.org/PathwayBrowser/#/R-BTA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Bos taurus 30616 R-BTA-182969 https://reactome.org/PathwayBrowser/#/R-BTA-182969 Phosphorylation of CBL (EGFR:CBL) IEA Bos taurus 30616 R-BTA-183058 https://reactome.org/PathwayBrowser/#/R-BTA-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Bos taurus 30616 R-BTA-1855153 https://reactome.org/PathwayBrowser/#/R-BTA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Bos taurus 30616 R-BTA-1855157 https://reactome.org/PathwayBrowser/#/R-BTA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Bos taurus 30616 R-BTA-1855158 https://reactome.org/PathwayBrowser/#/R-BTA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Bos taurus 30616 R-BTA-1855162 https://reactome.org/PathwayBrowser/#/R-BTA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Bos taurus 30616 R-BTA-1855169 https://reactome.org/PathwayBrowser/#/R-BTA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Bos taurus 30616 R-BTA-1855172 https://reactome.org/PathwayBrowser/#/R-BTA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Bos taurus 30616 R-BTA-1855176 https://reactome.org/PathwayBrowser/#/R-BTA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Bos taurus 30616 R-BTA-1855179 https://reactome.org/PathwayBrowser/#/R-BTA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Bos taurus 30616 R-BTA-1855181 https://reactome.org/PathwayBrowser/#/R-BTA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Bos taurus 30616 R-BTA-1855182 https://reactome.org/PathwayBrowser/#/R-BTA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Bos taurus 30616 R-BTA-1855185 https://reactome.org/PathwayBrowser/#/R-BTA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 30616 R-BTA-1855193 https://reactome.org/PathwayBrowser/#/R-BTA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Bos taurus 30616 R-BTA-1855194 https://reactome.org/PathwayBrowser/#/R-BTA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Bos taurus 30616 R-BTA-1855197 https://reactome.org/PathwayBrowser/#/R-BTA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Bos taurus 30616 R-BTA-1855206 https://reactome.org/PathwayBrowser/#/R-BTA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 30616 R-BTA-1855207 https://reactome.org/PathwayBrowser/#/R-BTA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Bos taurus 30616 R-BTA-1855216 https://reactome.org/PathwayBrowser/#/R-BTA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Bos taurus 30616 R-BTA-1855223 https://reactome.org/PathwayBrowser/#/R-BTA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Bos taurus 30616 R-BTA-1855224 https://reactome.org/PathwayBrowser/#/R-BTA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Bos taurus 30616 R-BTA-1855227 https://reactome.org/PathwayBrowser/#/R-BTA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Bos taurus 30616 R-BTA-1855228 https://reactome.org/PathwayBrowser/#/R-BTA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 30616 R-BTA-1855230 https://reactome.org/PathwayBrowser/#/R-BTA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Bos taurus 30616 R-BTA-1855233 https://reactome.org/PathwayBrowser/#/R-BTA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Bos taurus 30616 R-BTA-1861595 https://reactome.org/PathwayBrowser/#/R-BTA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Bos taurus 30616 R-BTA-186786 https://reactome.org/PathwayBrowser/#/R-BTA-186786 Autophosphorylation of PDGF beta receptors IEA Bos taurus 30616 R-BTA-186800 https://reactome.org/PathwayBrowser/#/R-BTA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-187520 https://reactome.org/PathwayBrowser/#/R-BTA-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Bos taurus 30616 R-BTA-187688 https://reactome.org/PathwayBrowser/#/R-BTA-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Bos taurus 30616 R-BTA-187916 https://reactome.org/PathwayBrowser/#/R-BTA-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Bos taurus 30616 R-BTA-187948 https://reactome.org/PathwayBrowser/#/R-BTA-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Bos taurus 30616 R-BTA-187949 https://reactome.org/PathwayBrowser/#/R-BTA-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Bos taurus 30616 R-BTA-187959 https://reactome.org/PathwayBrowser/#/R-BTA-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Bos taurus 30616 R-BTA-188350 https://reactome.org/PathwayBrowser/#/R-BTA-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Bos taurus 30616 R-BTA-188390 https://reactome.org/PathwayBrowser/#/R-BTA-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Bos taurus 30616 R-BTA-190326 https://reactome.org/PathwayBrowser/#/R-BTA-190326 Autocatalytic phosphorylation of FGFR4 IEA Bos taurus 30616 R-BTA-190385 https://reactome.org/PathwayBrowser/#/R-BTA-190385 Autocatalytic phosphorylation of FGFR3b IEA Bos taurus 30616 R-BTA-190388 https://reactome.org/PathwayBrowser/#/R-BTA-190388 Autocatalytic phosphorylation of FGFR3c IEA Bos taurus 30616 R-BTA-190408 https://reactome.org/PathwayBrowser/#/R-BTA-190408 Autocatalytic phosphorylation of FGFR2b IEA Bos taurus 30616 R-BTA-190413 https://reactome.org/PathwayBrowser/#/R-BTA-190413 Autocatalytic phosphorylation of FGFR2c IEA Bos taurus 30616 R-BTA-190427 https://reactome.org/PathwayBrowser/#/R-BTA-190427 Autocatalytic phosphorylation of FGFR1b IEA Bos taurus 30616 R-BTA-190429 https://reactome.org/PathwayBrowser/#/R-BTA-190429 Autocatalytic phosphorylation of FGFR1c IEA Bos taurus 30616 R-BTA-191062 https://reactome.org/PathwayBrowser/#/R-BTA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Bos taurus 30616 R-BTA-191380 https://reactome.org/PathwayBrowser/#/R-BTA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Bos taurus 30616 R-BTA-191414 https://reactome.org/PathwayBrowser/#/R-BTA-191414 MVD decarboxylates MVA5PP to IPPP IEA Bos taurus 30616 R-BTA-191422 https://reactome.org/PathwayBrowser/#/R-BTA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Bos taurus 30616 R-BTA-191636 https://reactome.org/PathwayBrowser/#/R-BTA-191636 Phosphorylation of Cx43 by c-src IEA Bos taurus 30616 R-BTA-192137 https://reactome.org/PathwayBrowser/#/R-BTA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 30616 R-BTA-193362 https://reactome.org/PathwayBrowser/#/R-BTA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-193401 https://reactome.org/PathwayBrowser/#/R-BTA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 30616 R-BTA-193407 https://reactome.org/PathwayBrowser/#/R-BTA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 30616 R-BTA-193424 https://reactome.org/PathwayBrowser/#/R-BTA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 30616 R-BTA-193703 https://reactome.org/PathwayBrowser/#/R-BTA-193703 IKKbeta is activated IEA Bos taurus 30616 R-BTA-193705 https://reactome.org/PathwayBrowser/#/R-BTA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Bos taurus 30616 R-BTA-193711 https://reactome.org/PathwayBrowser/#/R-BTA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 30616 R-BTA-193727 https://reactome.org/PathwayBrowser/#/R-BTA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 30616 R-BTA-193743 https://reactome.org/PathwayBrowser/#/R-BTA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 30616 R-BTA-193766 https://reactome.org/PathwayBrowser/#/R-BTA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 30616 R-BTA-194153 https://reactome.org/PathwayBrowser/#/R-BTA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-195275 https://reactome.org/PathwayBrowser/#/R-BTA-195275 Phosphorylation of APC component of the destruction complex IEA Bos taurus 30616 R-BTA-195283 https://reactome.org/PathwayBrowser/#/R-BTA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Bos taurus 30616 R-BTA-195287 https://reactome.org/PathwayBrowser/#/R-BTA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Bos taurus 30616 R-BTA-195300 https://reactome.org/PathwayBrowser/#/R-BTA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Bos taurus 30616 R-BTA-195318 https://reactome.org/PathwayBrowser/#/R-BTA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Bos taurus 30616 R-BTA-1963581 https://reactome.org/PathwayBrowser/#/R-BTA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Bos taurus 30616 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 30616 R-BTA-1963586 https://reactome.org/PathwayBrowser/#/R-BTA-1963586 SRC family kinases phosphorylate ERBB2 IEA Bos taurus 30616 R-BTA-196753 https://reactome.org/PathwayBrowser/#/R-BTA-196753 2xPPCS ligates PPanK with Cys IEA Bos taurus 30616 R-BTA-196754 https://reactome.org/PathwayBrowser/#/R-BTA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Bos taurus 30616 R-BTA-196761 https://reactome.org/PathwayBrowser/#/R-BTA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Bos taurus 30616 R-BTA-196773 https://reactome.org/PathwayBrowser/#/R-BTA-196773 COASY phosphorylates DP-CoA IEA Bos taurus 30616 R-BTA-196857 https://reactome.org/PathwayBrowser/#/R-BTA-196857 PANK2 phosphorylates PanK IEA Bos taurus 30616 R-BTA-196929 https://reactome.org/PathwayBrowser/#/R-BTA-196929 FLAD1 phosphorylates FMN IEA Bos taurus 30616 R-BTA-196964 https://reactome.org/PathwayBrowser/#/R-BTA-196964 RFK:Mg2+ phosphorylates RIB IEA Bos taurus 30616 R-BTA-197198 https://reactome.org/PathwayBrowser/#/R-BTA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Bos taurus 30616 R-BTA-197235 https://reactome.org/PathwayBrowser/#/R-BTA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 30616 R-BTA-197271 https://reactome.org/PathwayBrowser/#/R-BTA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Bos taurus 30616 R-BTA-197958 https://reactome.org/PathwayBrowser/#/R-BTA-197958 FPGS-2 transforms THF to THFPG IEA Bos taurus 30616 R-BTA-198266 https://reactome.org/PathwayBrowser/#/R-BTA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Bos taurus 30616 R-BTA-198314 https://reactome.org/PathwayBrowser/#/R-BTA-198314 DAG stimulates protein kinase C-delta IEA Bos taurus 30616 R-BTA-198669 https://reactome.org/PathwayBrowser/#/R-BTA-198669 p38MAPK phosphorylates MSK1 IEA Bos taurus 30616 R-BTA-198746 https://reactome.org/PathwayBrowser/#/R-BTA-198746 ERK1/2/5 activate RSK1/2/3 IEA Bos taurus 30616 R-BTA-198756 https://reactome.org/PathwayBrowser/#/R-BTA-198756 ERK1/2 phosphorylates MSK1 IEA Bos taurus 30616 R-BTA-199203 https://reactome.org/PathwayBrowser/#/R-BTA-199203 PANK1/3 phosphorylate PanK IEA Bos taurus 30616 R-BTA-199895 https://reactome.org/PathwayBrowser/#/R-BTA-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Bos taurus 30616 R-BTA-199910 https://reactome.org/PathwayBrowser/#/R-BTA-199910 MSK1 activates ATF1 IEA Bos taurus 30616 R-BTA-199917 https://reactome.org/PathwayBrowser/#/R-BTA-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Bos taurus 30616 R-BTA-199935 https://reactome.org/PathwayBrowser/#/R-BTA-199935 MSK1 activates CREB IEA Bos taurus 30616 R-BTA-200318 https://reactome.org/PathwayBrowser/#/R-BTA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Bos taurus 30616 R-BTA-200326 https://reactome.org/PathwayBrowser/#/R-BTA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Bos taurus 30616 R-BTA-200421 https://reactome.org/PathwayBrowser/#/R-BTA-200421 Activation of cytosolic AMPK by phosphorylation IEA Bos taurus 30616 R-BTA-200423 https://reactome.org/PathwayBrowser/#/R-BTA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Bos taurus 30616 R-BTA-200474 https://reactome.org/PathwayBrowser/#/R-BTA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 30616 R-BTA-200512 https://reactome.org/PathwayBrowser/#/R-BTA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 30616 R-BTA-200555 https://reactome.org/PathwayBrowser/#/R-BTA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Bos taurus 30616 R-BTA-200681 https://reactome.org/PathwayBrowser/#/R-BTA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Bos taurus 30616 R-BTA-200682 https://reactome.org/PathwayBrowser/#/R-BTA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Bos taurus 30616 R-BTA-200711 https://reactome.org/PathwayBrowser/#/R-BTA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Bos taurus 30616 R-BTA-201035 https://reactome.org/PathwayBrowser/#/R-BTA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Bos taurus 30616 R-BTA-201443 https://reactome.org/PathwayBrowser/#/R-BTA-201443 Type II receptor phosphorylates type I receptor IEA Bos taurus 30616 R-BTA-201476 https://reactome.org/PathwayBrowser/#/R-BTA-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Bos taurus 30616 R-BTA-201510 https://reactome.org/PathwayBrowser/#/R-BTA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Bos taurus 30616 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 30616 R-BTA-201677 https://reactome.org/PathwayBrowser/#/R-BTA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Bos taurus 30616 R-BTA-201717 https://reactome.org/PathwayBrowser/#/R-BTA-201717 CSNK2-mediated phosphorylation of DVL IEA Bos taurus 30616 R-BTA-202111 https://reactome.org/PathwayBrowser/#/R-BTA-202111 AKT1 phosphorylates eNOS IEA Bos taurus 30616 R-BTA-202165 https://reactome.org/PathwayBrowser/#/R-BTA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Bos taurus 30616 R-BTA-202168 https://reactome.org/PathwayBrowser/#/R-BTA-202168 Phosphorylation of ZAP-70 by Lck IEA Bos taurus 30616 R-BTA-202174 https://reactome.org/PathwayBrowser/#/R-BTA-202174 Activation of ZAP-70 IEA Bos taurus 30616 R-BTA-202216 https://reactome.org/PathwayBrowser/#/R-BTA-202216 Phosphorylation of SLP-76 IEA Bos taurus 30616 R-BTA-202222 https://reactome.org/PathwayBrowser/#/R-BTA-202222 Phosphorylation of PKC theta IEA Bos taurus 30616 R-BTA-202233 https://reactome.org/PathwayBrowser/#/R-BTA-202233 Inactivation of Lck by Csk IEA Bos taurus 30616 R-BTA-202245 https://reactome.org/PathwayBrowser/#/R-BTA-202245 Phosphorylation of TBSMs in LAT IEA Bos taurus 30616 R-BTA-202248 https://reactome.org/PathwayBrowser/#/R-BTA-202248 Phosphorylation of PLC-gamma1 IEA Bos taurus 30616 R-BTA-202291 https://reactome.org/PathwayBrowser/#/R-BTA-202291 Activation of Lck IEA Bos taurus 30616 R-BTA-202307 https://reactome.org/PathwayBrowser/#/R-BTA-202307 Change of PKC theta conformation IEA Bos taurus 30616 R-BTA-202365 https://reactome.org/PathwayBrowser/#/R-BTA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-202437 https://reactome.org/PathwayBrowser/#/R-BTA-202437 Phosphorylation of CARMA1 IEA Bos taurus 30616 R-BTA-202459 https://reactome.org/PathwayBrowser/#/R-BTA-202459 Phosphorylation of Bcl10 IEA Bos taurus 30616 R-BTA-202500 https://reactome.org/PathwayBrowser/#/R-BTA-202500 Activation of IKK complex IEA Bos taurus 30616 R-BTA-202510 https://reactome.org/PathwayBrowser/#/R-BTA-202510 Activation of TAK1-TAB2 complex IEA Bos taurus 30616 R-BTA-202541 https://reactome.org/PathwayBrowser/#/R-BTA-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Bos taurus 30616 R-BTA-2028284 https://reactome.org/PathwayBrowser/#/R-BTA-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Bos taurus 30616 R-BTA-2028555 https://reactome.org/PathwayBrowser/#/R-BTA-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Bos taurus 30616 R-BTA-2028583 https://reactome.org/PathwayBrowser/#/R-BTA-2028583 Phosphorylation of YAP by LATS2 IEA Bos taurus 30616 R-BTA-2028589 https://reactome.org/PathwayBrowser/#/R-BTA-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Bos taurus 30616 R-BTA-2028591 https://reactome.org/PathwayBrowser/#/R-BTA-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Bos taurus 30616 R-BTA-2028598 https://reactome.org/PathwayBrowser/#/R-BTA-2028598 Phosphorylation of YAP by LATS1 IEA Bos taurus 30616 R-BTA-2028629 https://reactome.org/PathwayBrowser/#/R-BTA-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Bos taurus 30616 R-BTA-2028635 https://reactome.org/PathwayBrowser/#/R-BTA-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Bos taurus 30616 R-BTA-2028661 https://reactome.org/PathwayBrowser/#/R-BTA-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Bos taurus 30616 R-BTA-2028670 https://reactome.org/PathwayBrowser/#/R-BTA-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Bos taurus 30616 R-BTA-2028673 https://reactome.org/PathwayBrowser/#/R-BTA-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Bos taurus 30616 R-BTA-2028675 https://reactome.org/PathwayBrowser/#/R-BTA-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Bos taurus 30616 R-BTA-2028679 https://reactome.org/PathwayBrowser/#/R-BTA-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Bos taurus 30616 R-BTA-2029268 https://reactome.org/PathwayBrowser/#/R-BTA-2029268 Phosphorylation and activation of PLCG IEA Bos taurus 30616 R-BTA-2029271 https://reactome.org/PathwayBrowser/#/R-BTA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-2029453 https://reactome.org/PathwayBrowser/#/R-BTA-2029453 Phosphorylation of VAV IEA Bos taurus 30616 R-BTA-2029454 https://reactome.org/PathwayBrowser/#/R-BTA-2029454 Autophosphorylation of PAK1 IEA Bos taurus 30616 R-BTA-2029459 https://reactome.org/PathwayBrowser/#/R-BTA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Bos taurus 30616 R-BTA-2029460 https://reactome.org/PathwayBrowser/#/R-BTA-2029460 PAK1 phosphorylates LIMK1 IEA Bos taurus 30616 R-BTA-2029466 https://reactome.org/PathwayBrowser/#/R-BTA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Bos taurus 30616 R-BTA-2029469 https://reactome.org/PathwayBrowser/#/R-BTA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Bos taurus 30616 R-BTA-2029473 https://reactome.org/PathwayBrowser/#/R-BTA-2029473 Branching and elongation of mother and daughter filaments IEA Bos taurus 30616 R-BTA-2029476 https://reactome.org/PathwayBrowser/#/R-BTA-2029476 Role of myosins in phagosome formation IEA Bos taurus 30616 R-BTA-203070 https://reactome.org/PathwayBrowser/#/R-BTA-203070 Association of profilin with monomeric actin IEA Bos taurus 30616 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 30616 R-BTA-2046085 https://reactome.org/PathwayBrowser/#/R-BTA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Bos taurus 30616 R-BTA-2046087 https://reactome.org/PathwayBrowser/#/R-BTA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Bos taurus 30616 R-BTA-2046093 https://reactome.org/PathwayBrowser/#/R-BTA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Bos taurus 30616 R-BTA-2046098 https://reactome.org/PathwayBrowser/#/R-BTA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Bos taurus 30616 R-BTA-205075 https://reactome.org/PathwayBrowser/#/R-BTA-205075 JNK phosphorylates BIM, BAD and other targets IEA Bos taurus 30616 R-BTA-205136 https://reactome.org/PathwayBrowser/#/R-BTA-205136 GTP-bound RAC contributes to JNK activation IEA Bos taurus 30616 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 30616 R-BTA-2060328 https://reactome.org/PathwayBrowser/#/R-BTA-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Bos taurus 30616 R-BTA-209087 https://reactome.org/PathwayBrowser/#/R-BTA-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Bos taurus 30616 R-BTA-210291 https://reactome.org/PathwayBrowser/#/R-BTA-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Bos taurus 30616 R-BTA-212710 https://reactome.org/PathwayBrowser/#/R-BTA-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Bos taurus 30616 R-BTA-2130194 https://reactome.org/PathwayBrowser/#/R-BTA-2130194 ABL phosphorylates WAVEs IEA Bos taurus 30616 R-BTA-216723 https://reactome.org/PathwayBrowser/#/R-BTA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Bos taurus 30616 R-BTA-216757 https://reactome.org/PathwayBrowser/#/R-BTA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Bos taurus 30616 R-BTA-2168079 https://reactome.org/PathwayBrowser/#/R-BTA-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Bos taurus 30616 R-BTA-2176475 https://reactome.org/PathwayBrowser/#/R-BTA-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Bos taurus 30616 R-BTA-2197690 https://reactome.org/PathwayBrowser/#/R-BTA-2197690 Detachment of WASP/WAVE IEA Bos taurus 30616 R-BTA-2197698 https://reactome.org/PathwayBrowser/#/R-BTA-2197698 Src phosphorylate WASP,N-WASP IEA Bos taurus 30616 R-BTA-2213248 https://reactome.org/PathwayBrowser/#/R-BTA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Bos taurus 30616 R-BTA-2214351 https://reactome.org/PathwayBrowser/#/R-BTA-2214351 PLK1 phosphorylates GORASP1 IEA Bos taurus 30616 R-BTA-2245218 https://reactome.org/PathwayBrowser/#/R-BTA-2245218 CDK1 phosphorylates PHF8 IEA Bos taurus 30616 R-BTA-2267372 https://reactome.org/PathwayBrowser/#/R-BTA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Bos taurus 30616 R-BTA-2294580 https://reactome.org/PathwayBrowser/#/R-BTA-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Bos taurus 30616 R-BTA-2294600 https://reactome.org/PathwayBrowser/#/R-BTA-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Bos taurus 30616 R-BTA-2316434 https://reactome.org/PathwayBrowser/#/R-BTA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-2396002 https://reactome.org/PathwayBrowser/#/R-BTA-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex IEA Bos taurus 30616 R-BTA-2396007 https://reactome.org/PathwayBrowser/#/R-BTA-2396007 IRF3 is phosphorylated by TBK1 IEA Bos taurus 30616 R-BTA-2404193 https://reactome.org/PathwayBrowser/#/R-BTA-2404193 IGF1R phosphorylates SHC1 IEA Bos taurus 30616 R-BTA-2404199 https://reactome.org/PathwayBrowser/#/R-BTA-2404199 IGF1,2:IGF1R autophosphorylates IEA Bos taurus 30616 R-BTA-2408551 https://reactome.org/PathwayBrowser/#/R-BTA-2408551 SeMet is converted to AdoSeMet by MAT IEA Bos taurus 30616 R-BTA-2422927 https://reactome.org/PathwayBrowser/#/R-BTA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Bos taurus 30616 R-BTA-2424480 https://reactome.org/PathwayBrowser/#/R-BTA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-2424487 https://reactome.org/PathwayBrowser/#/R-BTA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Bos taurus 30616 R-BTA-2428926 https://reactome.org/PathwayBrowser/#/R-BTA-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Bos taurus 30616 R-BTA-2430535 https://reactome.org/PathwayBrowser/#/R-BTA-2430535 MASTL phosphorylates ENSA IEA Bos taurus 30616 R-BTA-2454208 https://reactome.org/PathwayBrowser/#/R-BTA-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Bos taurus 30616 R-BTA-2466068 https://reactome.org/PathwayBrowser/#/R-BTA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Bos taurus 30616 R-BTA-2466767 https://reactome.org/PathwayBrowser/#/R-BTA-2466767 NRPE is a substrate for Abca4 TAS Bos taurus 30616 R-BTA-2468287 https://reactome.org/PathwayBrowser/#/R-BTA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Bos taurus 30616 R-BTA-2468293 https://reactome.org/PathwayBrowser/#/R-BTA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Bos taurus 30616 R-BTA-2529020 https://reactome.org/PathwayBrowser/#/R-BTA-2529020 CK2 phosphorylates condensin I subunits IEA Bos taurus 30616 R-BTA-2562526 https://reactome.org/PathwayBrowser/#/R-BTA-2562526 PLK1 phosphorylates OPTN IEA Bos taurus 30616 R-BTA-2574840 https://reactome.org/PathwayBrowser/#/R-BTA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Bos taurus 30616 R-BTA-2581474 https://reactome.org/PathwayBrowser/#/R-BTA-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Bos taurus 30616 R-BTA-265682 https://reactome.org/PathwayBrowser/#/R-BTA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Bos taurus 30616 R-BTA-265783 https://reactome.org/PathwayBrowser/#/R-BTA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-266082 https://reactome.org/PathwayBrowser/#/R-BTA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Bos taurus 30616 R-BTA-2730833 https://reactome.org/PathwayBrowser/#/R-BTA-2730833 Phosphorylation of TEC kinases by p-SYK IEA Bos taurus 30616 R-BTA-2730835 https://reactome.org/PathwayBrowser/#/R-BTA-2730835 Autophosphorylation of PKC-theta IEA Bos taurus 30616 R-BTA-2730841 https://reactome.org/PathwayBrowser/#/R-BTA-2730841 Phosphorylation and activation of VAV IEA Bos taurus 30616 R-BTA-2730843 https://reactome.org/PathwayBrowser/#/R-BTA-2730843 Phosphorylation of LAT by p-SYK IEA Bos taurus 30616 R-BTA-2730851 https://reactome.org/PathwayBrowser/#/R-BTA-2730851 Phosphorylation of SLP-76 by p-SYK IEA Bos taurus 30616 R-BTA-2730856 https://reactome.org/PathwayBrowser/#/R-BTA-2730856 Autophosphorylation of PAK IEA Bos taurus 30616 R-BTA-2730858 https://reactome.org/PathwayBrowser/#/R-BTA-2730858 Autophosphorylation of BTK/ITK IEA Bos taurus 30616 R-BTA-2730862 https://reactome.org/PathwayBrowser/#/R-BTA-2730862 Autophosphorylation of LYN kinase IEA Bos taurus 30616 R-BTA-2730863 https://reactome.org/PathwayBrowser/#/R-BTA-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Bos taurus 30616 R-BTA-2730870 https://reactome.org/PathwayBrowser/#/R-BTA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Bos taurus 30616 R-BTA-2730876 https://reactome.org/PathwayBrowser/#/R-BTA-2730876 Phosphorylation of IKK-beta by TAK1 IEA Bos taurus 30616 R-BTA-2730882 https://reactome.org/PathwayBrowser/#/R-BTA-2730882 Phosphorylation of PKC-theta IEA Bos taurus 30616 R-BTA-2730884 https://reactome.org/PathwayBrowser/#/R-BTA-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Bos taurus 30616 R-BTA-2730886 https://reactome.org/PathwayBrowser/#/R-BTA-2730886 Phosphorylation of SHC by SYK kinase IEA Bos taurus 30616 R-BTA-2730896 https://reactome.org/PathwayBrowser/#/R-BTA-2730896 Phosphorylation of MEK4 by MEKK1 IEA Bos taurus 30616 R-BTA-2730900 https://reactome.org/PathwayBrowser/#/R-BTA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Bos taurus 30616 R-BTA-2855020 https://reactome.org/PathwayBrowser/#/R-BTA-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Bos taurus 30616 R-BTA-2984220 https://reactome.org/PathwayBrowser/#/R-BTA-2984220 CDK1:CCNB phosphorylates NEK9 IEA Bos taurus 30616 R-BTA-2984226 https://reactome.org/PathwayBrowser/#/R-BTA-2984226 PLK1 phosphorylates NEK9 IEA Bos taurus 30616 R-BTA-2984258 https://reactome.org/PathwayBrowser/#/R-BTA-2984258 NEK9 phosphorylates NEK6/NEK7 IEA Bos taurus 30616 R-BTA-2990833 https://reactome.org/PathwayBrowser/#/R-BTA-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Bos taurus 30616 R-BTA-2990880 https://reactome.org/PathwayBrowser/#/R-BTA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Bos taurus 30616 R-BTA-2990882 https://reactome.org/PathwayBrowser/#/R-BTA-2990882 CDK1 phosphorylates NUP98 IEA Bos taurus 30616 R-BTA-2993447 https://reactome.org/PathwayBrowser/#/R-BTA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Bos taurus 30616 R-BTA-2993799 https://reactome.org/PathwayBrowser/#/R-BTA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Bos taurus 30616 R-BTA-2993802 https://reactome.org/PathwayBrowser/#/R-BTA-2993802 HLCS biotinylates PC:Mn2+ IEA Bos taurus 30616 R-BTA-2993814 https://reactome.org/PathwayBrowser/#/R-BTA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Bos taurus 30616 R-BTA-2993898 https://reactome.org/PathwayBrowser/#/R-BTA-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Bos taurus 30616 R-BTA-3000310 https://reactome.org/PathwayBrowser/#/R-BTA-3000310 AURKA phosphorylates PLK1 IEA Bos taurus 30616 R-BTA-3000327 https://reactome.org/PathwayBrowser/#/R-BTA-3000327 PLK1 phosphorylates BORA IEA Bos taurus 30616 R-BTA-3095901 https://reactome.org/PathwayBrowser/#/R-BTA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Bos taurus 30616 R-BTA-3132737 https://reactome.org/PathwayBrowser/#/R-BTA-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Bos taurus 30616 R-BTA-3159253 https://reactome.org/PathwayBrowser/#/R-BTA-3159253 MMAB adenosylates cob(I)alamin IEA Bos taurus 30616 R-BTA-3222006 https://reactome.org/PathwayBrowser/#/R-BTA-3222006 STK11 (LKB1) phosphorylates NUAK1 IEA Bos taurus 30616 R-BTA-3222020 https://reactome.org/PathwayBrowser/#/R-BTA-3222020 NUAK1 phosphorylates TP53 IEA Bos taurus 30616 R-BTA-3228469 https://reactome.org/PathwayBrowser/#/R-BTA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Bos taurus 30616 R-BTA-3229102 https://reactome.org/PathwayBrowser/#/R-BTA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Bos taurus 30616 R-BTA-3238999 https://reactome.org/PathwayBrowser/#/R-BTA-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Bos taurus 30616 R-BTA-3239014 https://reactome.org/PathwayBrowser/#/R-BTA-3239014 MAPKAPK5 phosphorylates TP53 IEA Bos taurus 30616 R-BTA-3239019 https://reactome.org/PathwayBrowser/#/R-BTA-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Bos taurus 30616 R-BTA-3249371 https://reactome.org/PathwayBrowser/#/R-BTA-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Bos taurus 30616 R-BTA-3249379 https://reactome.org/PathwayBrowser/#/R-BTA-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Bos taurus 30616 R-BTA-3249390 https://reactome.org/PathwayBrowser/#/R-BTA-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Bos taurus 30616 R-BTA-3371422 https://reactome.org/PathwayBrowser/#/R-BTA-3371422 ATP hydrolysis by HSP70 IEA Bos taurus 30616 R-BTA-3371435 https://reactome.org/PathwayBrowser/#/R-BTA-3371435 Constitutive phosphorylation by GSK3 IEA Bos taurus 30616 R-BTA-3371531 https://reactome.org/PathwayBrowser/#/R-BTA-3371531 Constitutive phosphorylation by pERK1/2 IEA Bos taurus 30616 R-BTA-3371590 https://reactome.org/PathwayBrowser/#/R-BTA-3371590 HSP70 binds to HSP40:nascent protein IEA Bos taurus 30616 R-BTA-349444 https://reactome.org/PathwayBrowser/#/R-BTA-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Bos taurus 30616 R-BTA-354073 https://reactome.org/PathwayBrowser/#/R-BTA-354073 Autophosphorylation of PTK2 at Y397 IEA Bos taurus 30616 R-BTA-354124 https://reactome.org/PathwayBrowser/#/R-BTA-354124 Phosphorylation of pPTK2 by SRC IEA Bos taurus 30616 R-BTA-372693 https://reactome.org/PathwayBrowser/#/R-BTA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Bos taurus 30616 R-BTA-373747 https://reactome.org/PathwayBrowser/#/R-BTA-373747 Phosphorylation of nephrin by FYN IEA Bos taurus 30616 R-BTA-373750 https://reactome.org/PathwayBrowser/#/R-BTA-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Bos taurus 30616 R-BTA-374664 https://reactome.org/PathwayBrowser/#/R-BTA-374664 Phosphorylation and activation of Ezrin IEA Bos taurus 30616 R-BTA-374701 https://reactome.org/PathwayBrowser/#/R-BTA-374701 Phosphorylation of DCC by Fyn IEA Bos taurus 30616 R-BTA-3769394 https://reactome.org/PathwayBrowser/#/R-BTA-3769394 AKT phosphorylates CBY1 IEA Bos taurus 30616 R-BTA-3772435 https://reactome.org/PathwayBrowser/#/R-BTA-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Bos taurus 30616 R-BTA-3772436 https://reactome.org/PathwayBrowser/#/R-BTA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Bos taurus 30616 R-BTA-377640 https://reactome.org/PathwayBrowser/#/R-BTA-377640 Autophosphorylation of SRC IEA Bos taurus 30616 R-BTA-3788705 https://reactome.org/PathwayBrowser/#/R-BTA-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Bos taurus 30616 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 30616 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 30616 R-BTA-380272 https://reactome.org/PathwayBrowser/#/R-BTA-380272 Plk1-mediated phosphorylation of Nlp IEA Bos taurus 30616 R-BTA-380278 https://reactome.org/PathwayBrowser/#/R-BTA-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Bos taurus 30616 R-BTA-380780 https://reactome.org/PathwayBrowser/#/R-BTA-380780 Activation of Src IEA Bos taurus 30616 R-BTA-380927 https://reactome.org/PathwayBrowser/#/R-BTA-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Bos taurus 30616 R-BTA-381091 https://reactome.org/PathwayBrowser/#/R-BTA-381091 IRE1 dimer autophosphorylates IEA Bos taurus 30616 R-BTA-381111 https://reactome.org/PathwayBrowser/#/R-BTA-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Bos taurus 30616 R-BTA-382560 https://reactome.org/PathwayBrowser/#/R-BTA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Bos taurus 30616 R-BTA-382575 https://reactome.org/PathwayBrowser/#/R-BTA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Bos taurus 30616 R-BTA-383190 https://reactome.org/PathwayBrowser/#/R-BTA-383190 HCO3- transport through ion channel IEA Bos taurus 30616 R-BTA-3857329 https://reactome.org/PathwayBrowser/#/R-BTA-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Bos taurus 30616 R-BTA-388831 https://reactome.org/PathwayBrowser/#/R-BTA-388831 Phosphorylation of CD28 IEA Bos taurus 30616 R-BTA-388833 https://reactome.org/PathwayBrowser/#/R-BTA-388833 Phosphorylation of CTLA-4 IEA Bos taurus 30616 R-BTA-389083 https://reactome.org/PathwayBrowser/#/R-BTA-389083 Autophosphorylation of PDGF alpha receptors IEA Bos taurus 30616 R-BTA-389086 https://reactome.org/PathwayBrowser/#/R-BTA-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Bos taurus 30616 R-BTA-389158 https://reactome.org/PathwayBrowser/#/R-BTA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-389354 https://reactome.org/PathwayBrowser/#/R-BTA-389354 Activation of Vav1 IEA Bos taurus 30616 R-BTA-389622 https://reactome.org/PathwayBrowser/#/R-BTA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 30616 R-BTA-389632 https://reactome.org/PathwayBrowser/#/R-BTA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 30616 R-BTA-389652 https://reactome.org/PathwayBrowser/#/R-BTA-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Bos taurus 30616 R-BTA-389762 https://reactome.org/PathwayBrowser/#/R-BTA-389762 Phosphorylation of PD-1 IEA Bos taurus 30616 R-BTA-390593 https://reactome.org/PathwayBrowser/#/R-BTA-390593 ATP Hydrolysis By Myosin IEA Bos taurus 30616 R-BTA-390598 https://reactome.org/PathwayBrowser/#/R-BTA-390598 Myosin Binds ATP IEA Bos taurus 30616 R-BTA-392300 https://reactome.org/PathwayBrowser/#/R-BTA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-392530 https://reactome.org/PathwayBrowser/#/R-BTA-392530 p-S400-Cot phosphorylates NIK IEA Bos taurus 30616 R-BTA-3928578 https://reactome.org/PathwayBrowser/#/R-BTA-3928578 EPH receptors autophosphorylate IEA Bos taurus 30616 R-BTA-3928595 https://reactome.org/PathwayBrowser/#/R-BTA-3928595 N-WASP binds ARP2/3 and G-actin IEA Bos taurus 30616 R-BTA-3928604 https://reactome.org/PathwayBrowser/#/R-BTA-3928604 SFKs phosphorylate VAV2,3 IEA Bos taurus 30616 R-BTA-3928620 https://reactome.org/PathwayBrowser/#/R-BTA-3928620 PAK1 autophosphorylates IEA Bos taurus 30616 R-BTA-3928625 https://reactome.org/PathwayBrowser/#/R-BTA-3928625 PAKs autophosphorylate IEA Bos taurus 30616 R-BTA-3928640 https://reactome.org/PathwayBrowser/#/R-BTA-3928640 PAKs phosphorylate MLC IEA Bos taurus 30616 R-BTA-399939 https://reactome.org/PathwayBrowser/#/R-BTA-399939 Autophosphorylation of PAK IEA Bos taurus 30616 R-BTA-399944 https://reactome.org/PathwayBrowser/#/R-BTA-399944 Phosphorylation of CRMPs by Cdk5 IEA Bos taurus 30616 R-BTA-399947 https://reactome.org/PathwayBrowser/#/R-BTA-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Bos taurus 30616 R-BTA-399951 https://reactome.org/PathwayBrowser/#/R-BTA-399951 Phosphorylation of CRMPs by GSK3beta IEA Bos taurus 30616 R-BTA-399952 https://reactome.org/PathwayBrowser/#/R-BTA-399952 Phosphorylation of LIMK-1 by PAK IEA Bos taurus 30616 R-BTA-4085028 https://reactome.org/PathwayBrowser/#/R-BTA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Bos taurus 30616 R-BTA-4086410 https://reactome.org/PathwayBrowser/#/R-BTA-4086410 CDK1 phosphorylates BORA IEA Bos taurus 30616 R-BTA-4088024 https://reactome.org/PathwayBrowser/#/R-BTA-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Bos taurus 30616 R-BTA-4088134 https://reactome.org/PathwayBrowser/#/R-BTA-4088134 PLK1 phosphorylates FOXM1 IEA Bos taurus 30616 R-BTA-4093332 https://reactome.org/PathwayBrowser/#/R-BTA-4093332 p-EPHB phosphorylates SDC2 IEA Bos taurus 30616 R-BTA-416320 https://reactome.org/PathwayBrowser/#/R-BTA-416320 Trafficking of GluR1-containing AMPA receptors IEA Bos taurus 30616 R-BTA-416639 https://reactome.org/PathwayBrowser/#/R-BTA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Bos taurus 30616 R-BTA-4167511 https://reactome.org/PathwayBrowser/#/R-BTA-4167511 HLCS biotinylates ACACB IEA Bos taurus 30616 R-BTA-416985 https://reactome.org/PathwayBrowser/#/R-BTA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Bos taurus 30616 R-BTA-417825 https://reactome.org/PathwayBrowser/#/R-BTA-417825 P2Y11 receptor can bind to ATP IEA Bos taurus 30616 R-BTA-417927 https://reactome.org/PathwayBrowser/#/R-BTA-417927 P2Y2 receptor binds ATP and UTP IEA Bos taurus 30616 R-BTA-418845 https://reactome.org/PathwayBrowser/#/R-BTA-418845 Activation of caspase-3 IEA Bos taurus 30616 R-BTA-419490 https://reactome.org/PathwayBrowser/#/R-BTA-419490 Binding of ATP to P2X receptors IEA Bos taurus 30616 R-BTA-419644 https://reactome.org/PathwayBrowser/#/R-BTA-419644 Transphosphorylation of pLIMK1 IEA Bos taurus 30616 R-BTA-419646 https://reactome.org/PathwayBrowser/#/R-BTA-419646 SEMA4D interacts with Plexin-B1:Met IEA Bos taurus 30616 R-BTA-421007 https://reactome.org/PathwayBrowser/#/R-BTA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Bos taurus 30616 R-BTA-426240 https://reactome.org/PathwayBrowser/#/R-BTA-426240 DAG kinase produces phosphatidic acid from DAG IEA Bos taurus 30616 R-BTA-428273 https://reactome.org/PathwayBrowser/#/R-BTA-428273 SPHK1 phosphorylates sphingoid IEA Bos taurus 30616 R-BTA-428888 https://reactome.org/PathwayBrowser/#/R-BTA-428888 Phosphorylation of ROBO1 by ABL kinase IEA Bos taurus 30616 R-BTA-428941 https://reactome.org/PathwayBrowser/#/R-BTA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Bos taurus 30616 R-BTA-428961 https://reactome.org/PathwayBrowser/#/R-BTA-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Bos taurus 30616 R-BTA-429016 https://reactome.org/PathwayBrowser/#/R-BTA-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Bos taurus 30616 R-BTA-429157 https://reactome.org/PathwayBrowser/#/R-BTA-429157 ABCC4 accumulation of dense granule contents IEA Bos taurus 30616 R-BTA-429441 https://reactome.org/PathwayBrowser/#/R-BTA-429441 SYK activation by SRC IEA Bos taurus 30616 R-BTA-429449 https://reactome.org/PathwayBrowser/#/R-BTA-429449 Syk activation leads to SLP-76 activation IEA Bos taurus 30616 R-BTA-429698 https://reactome.org/PathwayBrowser/#/R-BTA-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Bos taurus 30616 R-BTA-429714 https://reactome.org/PathwayBrowser/#/R-BTA-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Bos taurus 30616 R-BTA-430347 https://reactome.org/PathwayBrowser/#/R-BTA-430347 MigFilin associates with Filamin and F-actin IEA Bos taurus 30616 R-BTA-432129 https://reactome.org/PathwayBrowser/#/R-BTA-432129 FGR binds and phosphorylates LRP8 IEA Bos taurus 30616 R-BTA-432148 https://reactome.org/PathwayBrowser/#/R-BTA-432148 Fgr may phosphorylate p38 MAPK IEA Bos taurus 30616 R-BTA-432232 https://reactome.org/PathwayBrowser/#/R-BTA-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Bos taurus 30616 R-BTA-4332358 https://reactome.org/PathwayBrowser/#/R-BTA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Bos taurus 30616 R-BTA-4332363 https://reactome.org/PathwayBrowser/#/R-BTA-4332363 Autophosphorylation and activation of CAMK2 IEA Bos taurus 30616 R-BTA-434382 https://reactome.org/PathwayBrowser/#/R-BTA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Bos taurus 30616 R-BTA-434836 https://reactome.org/PathwayBrowser/#/R-BTA-434836 Syk/Lck phosphorylate LAT IEA Bos taurus 30616 R-BTA-435244 https://reactome.org/PathwayBrowser/#/R-BTA-435244 PECAM1 is phosphorylated IEA Bos taurus 30616 R-BTA-437162 https://reactome.org/PathwayBrowser/#/R-BTA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-4411383 https://reactome.org/PathwayBrowser/#/R-BTA-4411383 NLK phosphorylates TCF/LEF IEA Bos taurus 30616 R-BTA-4411402 https://reactome.org/PathwayBrowser/#/R-BTA-4411402 Activation of NLK IEA Bos taurus 30616 R-BTA-4420117 https://reactome.org/PathwayBrowser/#/R-BTA-4420117 VEGFR2 autophosphorylates IEA Bos taurus 30616 R-BTA-4420121 https://reactome.org/PathwayBrowser/#/R-BTA-4420121 SFKs phosphorylate PLCG1 IEA Bos taurus 30616 R-BTA-4420128 https://reactome.org/PathwayBrowser/#/R-BTA-4420128 SRC-1 phosphorylates SHB IEA Bos taurus 30616 R-BTA-4420206 https://reactome.org/PathwayBrowser/#/R-BTA-4420206 Phosphorylation of SRC-1 IEA Bos taurus 30616 R-BTA-442724 https://reactome.org/PathwayBrowser/#/R-BTA-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Bos taurus 30616 R-BTA-442749 https://reactome.org/PathwayBrowser/#/R-BTA-442749 CaMKK autophosphorylates in the nucleus IEA Bos taurus 30616 R-BTA-445072 https://reactome.org/PathwayBrowser/#/R-BTA-445072 Interaction of PAK1 with Rac1-GTP IEA Bos taurus 30616 R-BTA-445079 https://reactome.org/PathwayBrowser/#/R-BTA-445079 Phosphorylation of L1 by ERK IEA Bos taurus 30616 R-BTA-445699 https://reactome.org/PathwayBrowser/#/R-BTA-445699 ATP Hydrolysis By Myosin IEA Bos taurus 30616 R-BTA-445700 https://reactome.org/PathwayBrowser/#/R-BTA-445700 Myosin Binds ATP IEA Bos taurus 30616 R-BTA-445813 https://reactome.org/PathwayBrowser/#/R-BTA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Bos taurus 30616 R-BTA-446634 https://reactome.org/PathwayBrowser/#/R-BTA-446634 IRAK4 is activated by autophosphorylation IEA Bos taurus 30616 R-BTA-446694 https://reactome.org/PathwayBrowser/#/R-BTA-446694 IRAK4 phosphorylates IRAK1 IEA Bos taurus 30616 R-BTA-446701 https://reactome.org/PathwayBrowser/#/R-BTA-446701 IRAK4-activated IRAK1 autophosphorylates IEA Bos taurus 30616 R-BTA-447074 https://reactome.org/PathwayBrowser/#/R-BTA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Bos taurus 30616 R-BTA-448955 https://reactome.org/PathwayBrowser/#/R-BTA-448955 Phosphorylation of MEF2 proteins by p38 IEA Bos taurus 30616 R-BTA-449911 https://reactome.org/PathwayBrowser/#/R-BTA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Bos taurus 30616 R-BTA-450088 https://reactome.org/PathwayBrowser/#/R-BTA-450088 GLUT1 tetramer binds 4xATP IEA Bos taurus 30616 R-BTA-450092 https://reactome.org/PathwayBrowser/#/R-BTA-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Bos taurus 30616 R-BTA-450222 https://reactome.org/PathwayBrowser/#/R-BTA-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Bos taurus 30616 R-BTA-450325 https://reactome.org/PathwayBrowser/#/R-BTA-450325 c-FOS activation by phospho ERK1/2 IEA Bos taurus 30616 R-BTA-450333 https://reactome.org/PathwayBrowser/#/R-BTA-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Bos taurus 30616 R-BTA-450337 https://reactome.org/PathwayBrowser/#/R-BTA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Bos taurus 30616 R-BTA-450346 https://reactome.org/PathwayBrowser/#/R-BTA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Bos taurus 30616 R-BTA-450463 https://reactome.org/PathwayBrowser/#/R-BTA-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Bos taurus 30616 R-BTA-450474 https://reactome.org/PathwayBrowser/#/R-BTA-450474 MK2 phosphorylates BRF1 IEA Bos taurus 30616 R-BTA-450533 https://reactome.org/PathwayBrowser/#/R-BTA-450533 PKCdelta phosphorylates HuR IEA Bos taurus 30616 R-BTA-450827 https://reactome.org/PathwayBrowser/#/R-BTA-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Bos taurus 30616 R-BTA-451942 https://reactome.org/PathwayBrowser/#/R-BTA-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Bos taurus 30616 R-BTA-452097 https://reactome.org/PathwayBrowser/#/R-BTA-452097 Recruited STAT5 is phosphorylated IEA Bos taurus 30616 R-BTA-452100 https://reactome.org/PathwayBrowser/#/R-BTA-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Bos taurus 30616 R-BTA-452122 https://reactome.org/PathwayBrowser/#/R-BTA-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Bos taurus 30616 R-BTA-453200 https://reactome.org/PathwayBrowser/#/R-BTA-453200 SYK autophosphorylates IEA Bos taurus 30616 R-BTA-453342 https://reactome.org/PathwayBrowser/#/R-BTA-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Bos taurus 30616 R-BTA-4793911 https://reactome.org/PathwayBrowser/#/R-BTA-4793911 MAPKAPK2 phosphorylates HSF1 IEA Bos taurus 30616 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 30616 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 30616 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 30616 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 30616 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 30616 R-BTA-504054 https://reactome.org/PathwayBrowser/#/R-BTA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Bos taurus 30616 R-BTA-508040 https://reactome.org/PathwayBrowser/#/R-BTA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Bos taurus 30616 R-BTA-5082387 https://reactome.org/PathwayBrowser/#/R-BTA-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Bos taurus 30616 R-BTA-5082405 https://reactome.org/PathwayBrowser/#/R-BTA-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Bos taurus 30616 R-BTA-508282 https://reactome.org/PathwayBrowser/#/R-BTA-508282 SYK is a substrate for JAK1 IEA Bos taurus 30616 R-BTA-508308 https://reactome.org/PathwayBrowser/#/R-BTA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Bos taurus 30616 R-BTA-5138432 https://reactome.org/PathwayBrowser/#/R-BTA-5138432 DVL2 is phosphorylated by PKC IEA Bos taurus 30616 R-BTA-5195402 https://reactome.org/PathwayBrowser/#/R-BTA-5195402 CDK1 phosphorylates LPIN IEA Bos taurus 30616 R-BTA-5213464 https://reactome.org/PathwayBrowser/#/R-BTA-5213464 RIPK1 is phosphorylated IEA Bos taurus 30616 R-BTA-5213466 https://reactome.org/PathwayBrowser/#/R-BTA-5213466 RIPK3 is phosphorylated IEA Bos taurus 30616 R-BTA-5218640 https://reactome.org/PathwayBrowser/#/R-BTA-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Bos taurus 30616 R-BTA-5218642 https://reactome.org/PathwayBrowser/#/R-BTA-5218642 PTK2 autophosphorylates IEA Bos taurus 30616 R-BTA-5218804 https://reactome.org/PathwayBrowser/#/R-BTA-5218804 p38 MAPK activation by VEGFR IEA Bos taurus 30616 R-BTA-5218805 https://reactome.org/PathwayBrowser/#/R-BTA-5218805 PKC autophosphorylates IEA Bos taurus 30616 R-BTA-5218806 https://reactome.org/PathwayBrowser/#/R-BTA-5218806 FYN autophosphorylates IEA Bos taurus 30616 R-BTA-5218809 https://reactome.org/PathwayBrowser/#/R-BTA-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Bos taurus 30616 R-BTA-5218812 https://reactome.org/PathwayBrowser/#/R-BTA-5218812 FYN phosphorylates PAK2 IEA Bos taurus 30616 R-BTA-5218814 https://reactome.org/PathwayBrowser/#/R-BTA-5218814 PAK2 autophorylates IEA Bos taurus 30616 R-BTA-5218819 https://reactome.org/PathwayBrowser/#/R-BTA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-5218820 https://reactome.org/PathwayBrowser/#/R-BTA-5218820 Src kinases phosphorylate VAV IEA Bos taurus 30616 R-BTA-5218821 https://reactome.org/PathwayBrowser/#/R-BTA-5218821 PDK1 phosphorylates PKC IEA Bos taurus 30616 R-BTA-5218823 https://reactome.org/PathwayBrowser/#/R-BTA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Bos taurus 30616 R-BTA-5218826 https://reactome.org/PathwayBrowser/#/R-BTA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Bos taurus 30616 R-BTA-5218830 https://reactome.org/PathwayBrowser/#/R-BTA-5218830 SRC-1 phosphorylates PTK2-beta IEA Bos taurus 30616 R-BTA-5218845 https://reactome.org/PathwayBrowser/#/R-BTA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Bos taurus 30616 R-BTA-5218851 https://reactome.org/PathwayBrowser/#/R-BTA-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Bos taurus 30616 R-BTA-5218854 https://reactome.org/PathwayBrowser/#/R-BTA-5218854 p-Y420-FYN is phosphorylated on S21 IEA Bos taurus 30616 R-BTA-5218906 https://reactome.org/PathwayBrowser/#/R-BTA-5218906 RIPK3 phosphorylates MLKL IEA Bos taurus 30616 R-BTA-5218916 https://reactome.org/PathwayBrowser/#/R-BTA-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Bos taurus 30616 R-BTA-5223313 https://reactome.org/PathwayBrowser/#/R-BTA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Bos taurus 30616 R-BTA-5223317 https://reactome.org/PathwayBrowser/#/R-BTA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Bos taurus 30616 R-BTA-5229194 https://reactome.org/PathwayBrowser/#/R-BTA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Bos taurus 30616 R-BTA-5229343 https://reactome.org/PathwayBrowser/#/R-BTA-5229343 AXIN is phosphorylated in the destruction complex IEA Bos taurus 30616 R-BTA-5244669 https://reactome.org/PathwayBrowser/#/R-BTA-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Bos taurus 30616 R-BTA-5251942 https://reactome.org/PathwayBrowser/#/R-BTA-5251942 Hikeshi binds HSP70s:ATP IEA Bos taurus 30616 R-BTA-5251955 https://reactome.org/PathwayBrowser/#/R-BTA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Bos taurus 30616 R-BTA-5251959 https://reactome.org/PathwayBrowser/#/R-BTA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Bos taurus 30616 R-BTA-5251989 https://reactome.org/PathwayBrowser/#/R-BTA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Bos taurus 30616 R-BTA-5252041 https://reactome.org/PathwayBrowser/#/R-BTA-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Bos taurus 30616 R-BTA-5252079 https://reactome.org/PathwayBrowser/#/R-BTA-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Bos taurus 30616 R-BTA-5339524 https://reactome.org/PathwayBrowser/#/R-BTA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Bos taurus 30616 R-BTA-5357429 https://reactome.org/PathwayBrowser/#/R-BTA-5357429 AXL autophosphorylates on Y779 and Y821 IEA Bos taurus 30616 R-BTA-5357472 https://reactome.org/PathwayBrowser/#/R-BTA-5357472 PAK1-3 autophosphorylates IEA Bos taurus 30616 R-BTA-5357477 https://reactome.org/PathwayBrowser/#/R-BTA-5357477 PAK1-3 phosphorylates VE-cadherin IEA Bos taurus 30616 R-BTA-5357831 https://reactome.org/PathwayBrowser/#/R-BTA-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Bos taurus 30616 R-BTA-5358475 https://reactome.org/PathwayBrowser/#/R-BTA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Bos taurus 30616 R-BTA-5358510 https://reactome.org/PathwayBrowser/#/R-BTA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Bos taurus 30616 R-BTA-5358518 https://reactome.org/PathwayBrowser/#/R-BTA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Bos taurus 30616 R-BTA-5358592 https://reactome.org/PathwayBrowser/#/R-BTA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Bos taurus 30616 R-BTA-5358597 https://reactome.org/PathwayBrowser/#/R-BTA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Bos taurus 30616 R-BTA-5358599 https://reactome.org/PathwayBrowser/#/R-BTA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Bos taurus 30616 R-BTA-5358912 https://reactome.org/PathwayBrowser/#/R-BTA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Bos taurus 30616 R-BTA-5362459 https://reactome.org/PathwayBrowser/#/R-BTA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Bos taurus 30616 R-BTA-548843 https://reactome.org/PathwayBrowser/#/R-BTA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Bos taurus 30616 R-BTA-5603114 https://reactome.org/PathwayBrowser/#/R-BTA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Bos taurus 30616 R-BTA-5607722 https://reactome.org/PathwayBrowser/#/R-BTA-5607722 Active NIK phosphorylates IKKA dimer IEA Bos taurus 30616 R-BTA-5607726 https://reactome.org/PathwayBrowser/#/R-BTA-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Bos taurus 30616 R-BTA-5607732 https://reactome.org/PathwayBrowser/#/R-BTA-5607732 K63polyUb-TAK1 autophosphorylates IEA Bos taurus 30616 R-BTA-5607740 https://reactome.org/PathwayBrowser/#/R-BTA-5607740 PKC-delta phosphorylates CARD9 IEA Bos taurus 30616 R-BTA-5607742 https://reactome.org/PathwayBrowser/#/R-BTA-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Bos taurus 30616 R-BTA-5607750 https://reactome.org/PathwayBrowser/#/R-BTA-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Bos taurus 30616 R-BTA-5610720 https://reactome.org/PathwayBrowser/#/R-BTA-5610720 PKA phosphorylates GLI3 IEA Bos taurus 30616 R-BTA-5610722 https://reactome.org/PathwayBrowser/#/R-BTA-5610722 CK1 phosphorylates p-GLI3 IEA Bos taurus 30616 R-BTA-5610727 https://reactome.org/PathwayBrowser/#/R-BTA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Bos taurus 30616 R-BTA-5610732 https://reactome.org/PathwayBrowser/#/R-BTA-5610732 GSK3 phosphorylates p-GLI3 IEA Bos taurus 30616 R-BTA-5617182 https://reactome.org/PathwayBrowser/#/R-BTA-5617182 PRKACA phosphorylates PLN IEA Bos taurus 30616 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 30616 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 30616 R-BTA-5618085 https://reactome.org/PathwayBrowser/#/R-BTA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Bos taurus 30616 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 30616 R-BTA-5618098 https://reactome.org/PathwayBrowser/#/R-BTA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Bos taurus 30616 R-BTA-5618099 https://reactome.org/PathwayBrowser/#/R-BTA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Bos taurus 30616 R-BTA-5618105 https://reactome.org/PathwayBrowser/#/R-BTA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Bos taurus 30616 R-BTA-5618107 https://reactome.org/PathwayBrowser/#/R-BTA-5618107 ATP binding to HSP90 triggers conformation change IEA Bos taurus 30616 R-BTA-5618110 https://reactome.org/PathwayBrowser/#/R-BTA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Bos taurus 30616 R-BTA-5621355 https://reactome.org/PathwayBrowser/#/R-BTA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Bos taurus 30616 R-BTA-5621363 https://reactome.org/PathwayBrowser/#/R-BTA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Bos taurus 30616 R-BTA-5621370 https://reactome.org/PathwayBrowser/#/R-BTA-5621370 SYK autophosphorylates IEA Bos taurus 30616 R-BTA-5623667 https://reactome.org/PathwayBrowser/#/R-BTA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Bos taurus 30616 R-BTA-5624473 https://reactome.org/PathwayBrowser/#/R-BTA-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Bos taurus 30616 R-BTA-5625784 https://reactome.org/PathwayBrowser/#/R-BTA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Bos taurus 30616 R-BTA-5626507 https://reactome.org/PathwayBrowser/#/R-BTA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Bos taurus 30616 R-BTA-5627775 https://reactome.org/PathwayBrowser/#/R-BTA-5627775 Autophosphorylation of PAK1,2,3 IEA Bos taurus 30616 R-BTA-5635842 https://reactome.org/PathwayBrowser/#/R-BTA-5635842 ULK3 phosphorylates GLI IEA Bos taurus 30616 R-BTA-5654147 https://reactome.org/PathwayBrowser/#/R-BTA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Bos taurus 30616 R-BTA-5654149 https://reactome.org/PathwayBrowser/#/R-BTA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Bos taurus 30616 R-BTA-5654151 https://reactome.org/PathwayBrowser/#/R-BTA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Bos taurus 30616 R-BTA-5654222 https://reactome.org/PathwayBrowser/#/R-BTA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Bos taurus 30616 R-BTA-5654397 https://reactome.org/PathwayBrowser/#/R-BTA-5654397 Activated FGFR2 phosphorylates FRS2 IEA Bos taurus 30616 R-BTA-5654407 https://reactome.org/PathwayBrowser/#/R-BTA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Bos taurus 30616 R-BTA-5654408 https://reactome.org/PathwayBrowser/#/R-BTA-5654408 Activated FGFR3 phosphorylates FRS2 IEA Bos taurus 30616 R-BTA-5654418 https://reactome.org/PathwayBrowser/#/R-BTA-5654418 Activated FGFR4 phosphorylates FRS2 IEA Bos taurus 30616 R-BTA-5654428 https://reactome.org/PathwayBrowser/#/R-BTA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Bos taurus 30616 R-BTA-5654560 https://reactome.org/PathwayBrowser/#/R-BTA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Bos taurus 30616 R-BTA-5654562 https://reactome.org/PathwayBrowser/#/R-BTA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Bos taurus 30616 R-BTA-5654565 https://reactome.org/PathwayBrowser/#/R-BTA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Bos taurus 30616 R-BTA-5654566 https://reactome.org/PathwayBrowser/#/R-BTA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Bos taurus 30616 R-BTA-5654575 https://reactome.org/PathwayBrowser/#/R-BTA-5654575 Activated FGFR1 phosphorylates FRS2 IEA Bos taurus 30616 R-BTA-5654578 https://reactome.org/PathwayBrowser/#/R-BTA-5654578 Activated FGFR1 phosphorylates FRS3 IEA Bos taurus 30616 R-BTA-5654582 https://reactome.org/PathwayBrowser/#/R-BTA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Bos taurus 30616 R-BTA-5654587 https://reactome.org/PathwayBrowser/#/R-BTA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Bos taurus 30616 R-BTA-5654605 https://reactome.org/PathwayBrowser/#/R-BTA-5654605 Activated FGFR2 phosphorylates FRS3 IEA Bos taurus 30616 R-BTA-5654607 https://reactome.org/PathwayBrowser/#/R-BTA-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Bos taurus 30616 R-BTA-5654628 https://reactome.org/PathwayBrowser/#/R-BTA-5654628 Activated FGFR3 phosphorylates FRS3 IEA Bos taurus 30616 R-BTA-5654631 https://reactome.org/PathwayBrowser/#/R-BTA-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Bos taurus 30616 R-BTA-5654634 https://reactome.org/PathwayBrowser/#/R-BTA-5654634 Activated FGFR3 phosphorylates SHC1 IEA Bos taurus 30616 R-BTA-5654653 https://reactome.org/PathwayBrowser/#/R-BTA-5654653 Activated FGFR4 phosphorylates FRS3 IEA Bos taurus 30616 R-BTA-5654655 https://reactome.org/PathwayBrowser/#/R-BTA-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Bos taurus 30616 R-BTA-5654690 https://reactome.org/PathwayBrowser/#/R-BTA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-5654692 https://reactome.org/PathwayBrowser/#/R-BTA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-5654697 https://reactome.org/PathwayBrowser/#/R-BTA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-5654701 https://reactome.org/PathwayBrowser/#/R-BTA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-5654705 https://reactome.org/PathwayBrowser/#/R-BTA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-5654709 https://reactome.org/PathwayBrowser/#/R-BTA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-5654714 https://reactome.org/PathwayBrowser/#/R-BTA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-5654717 https://reactome.org/PathwayBrowser/#/R-BTA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-5654989 https://reactome.org/PathwayBrowser/#/R-BTA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Bos taurus 30616 R-BTA-5662466 https://reactome.org/PathwayBrowser/#/R-BTA-5662466 XYLB phosphorylates D-xylulose IEA Bos taurus 30616 R-BTA-5665751 https://reactome.org/PathwayBrowser/#/R-BTA-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin IEA Bos taurus 30616 R-BTA-5665767 https://reactome.org/PathwayBrowser/#/R-BTA-5665767 Activated FMNL3 binds G-actin IEA Bos taurus 30616 R-BTA-5665802 https://reactome.org/PathwayBrowser/#/R-BTA-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Bos taurus 30616 R-BTA-5665809 https://reactome.org/PathwayBrowser/#/R-BTA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Bos taurus 30616 R-BTA-5665868 https://reactome.org/PathwayBrowser/#/R-BTA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Bos taurus 30616 R-BTA-5666001 https://reactome.org/PathwayBrowser/#/R-BTA-5666001 Profilin:G-actin binds MKL1 IEA Bos taurus 30616 R-BTA-5666160 https://reactome.org/PathwayBrowser/#/R-BTA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Bos taurus 30616 R-BTA-5668545 https://reactome.org/PathwayBrowser/#/R-BTA-5668545 NIK autophosphorylates on T559 IEA Bos taurus 30616 R-BTA-5668932 https://reactome.org/PathwayBrowser/#/R-BTA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Bos taurus 30616 R-BTA-5668947 https://reactome.org/PathwayBrowser/#/R-BTA-5668947 PAK1 phosphorylates myosin phosphatase IEA Bos taurus 30616 R-BTA-5668984 https://reactome.org/PathwayBrowser/#/R-BTA-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Bos taurus 30616 R-BTA-5669250 https://reactome.org/PathwayBrowser/#/R-BTA-5669250 PAK1 phosphorylates FLNA IEA Bos taurus 30616 R-BTA-5671749 https://reactome.org/PathwayBrowser/#/R-BTA-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Bos taurus 30616 R-BTA-5671763 https://reactome.org/PathwayBrowser/#/R-BTA-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Bos taurus 30616 R-BTA-5672008 https://reactome.org/PathwayBrowser/#/R-BTA-5672008 Thr-180 of ULK1 is phosphorylated IEA Bos taurus 30616 R-BTA-5672010 https://reactome.org/PathwayBrowser/#/R-BTA-5672010 Active MTORC1 phosphorylates ULK1 IEA Bos taurus 30616 R-BTA-5672012 https://reactome.org/PathwayBrowser/#/R-BTA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Bos taurus 30616 R-BTA-5672027 https://reactome.org/PathwayBrowser/#/R-BTA-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Bos taurus 30616 R-BTA-5672828 https://reactome.org/PathwayBrowser/#/R-BTA-5672828 mTORC1 phosphorylates AKT1S1 IEA Bos taurus 30616 R-BTA-5672948 https://reactome.org/PathwayBrowser/#/R-BTA-5672948 MARK3 phosphorylates KSR1 IEA Bos taurus 30616 R-BTA-5672969 https://reactome.org/PathwayBrowser/#/R-BTA-5672969 Phosphorylation of RAF IEA Bos taurus 30616 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 30616 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 30616 R-BTA-5673768 https://reactome.org/PathwayBrowser/#/R-BTA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Bos taurus 30616 R-BTA-5674130 https://reactome.org/PathwayBrowser/#/R-BTA-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Bos taurus 30616 R-BTA-5674373 https://reactome.org/PathwayBrowser/#/R-BTA-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Bos taurus 30616 R-BTA-5674496 https://reactome.org/PathwayBrowser/#/R-BTA-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Bos taurus 30616 R-BTA-5675198 https://reactome.org/PathwayBrowser/#/R-BTA-5675198 Activated MAPKs phosphorylate BRAF IEA Bos taurus 30616 R-BTA-5675868 https://reactome.org/PathwayBrowser/#/R-BTA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Bos taurus 30616 R-BTA-5678706 https://reactome.org/PathwayBrowser/#/R-BTA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Bos taurus 30616 R-BTA-5678863 https://reactome.org/PathwayBrowser/#/R-BTA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-5679041 https://reactome.org/PathwayBrowser/#/R-BTA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-5679205 https://reactome.org/PathwayBrowser/#/R-BTA-5679205 ULK1 phosphorylates Beclin-1 IEA Bos taurus 30616 R-BTA-5682026 https://reactome.org/PathwayBrowser/#/R-BTA-5682026 MRN bound to shortened telomeres activates ATM IEA Bos taurus 30616 R-BTA-5682101 https://reactome.org/PathwayBrowser/#/R-BTA-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Bos taurus 30616 R-BTA-5682285 https://reactome.org/PathwayBrowser/#/R-BTA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-5682598 https://reactome.org/PathwayBrowser/#/R-BTA-5682598 ATM phosphorylates HERC2 IEA Bos taurus 30616 R-BTA-5682983 https://reactome.org/PathwayBrowser/#/R-BTA-5682983 ATM phosphorylates WHSC1 IEA Bos taurus 30616 R-BTA-5683425 https://reactome.org/PathwayBrowser/#/R-BTA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Bos taurus 30616 R-BTA-5683714 https://reactome.org/PathwayBrowser/#/R-BTA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Bos taurus 30616 R-BTA-5683792 https://reactome.org/PathwayBrowser/#/R-BTA-5683792 p-T68-CHEK2 autophosphorylates IEA Bos taurus 30616 R-BTA-5683801 https://reactome.org/PathwayBrowser/#/R-BTA-5683801 CHEK2 phosphorylates BRCA1 IEA Bos taurus 30616 R-BTA-5683930 https://reactome.org/PathwayBrowser/#/R-BTA-5683930 WICH phosphorylates H2AFX on Y142 IEA Bos taurus 30616 R-BTA-5683964 https://reactome.org/PathwayBrowser/#/R-BTA-5683964 ATM phosphorylates EYA1-4 IEA Bos taurus 30616 R-BTA-5684096 https://reactome.org/PathwayBrowser/#/R-BTA-5684096 CDK2 phosphorylates RBBP8 IEA Bos taurus 30616 R-BTA-5684140 https://reactome.org/PathwayBrowser/#/R-BTA-5684140 ATM phosphorylates RBBP8 IEA Bos taurus 30616 R-BTA-5684261 https://reactome.org/PathwayBrowser/#/R-BTA-5684261 MAP3K8 is phosphorylated IEA Bos taurus 30616 R-BTA-5684267 https://reactome.org/PathwayBrowser/#/R-BTA-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex IEA Bos taurus 30616 R-BTA-5684275 https://reactome.org/PathwayBrowser/#/R-BTA-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 IEA Bos taurus 30616 R-BTA-5684806 https://reactome.org/PathwayBrowser/#/R-BTA-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN IEA Bos taurus 30616 R-BTA-5684862 https://reactome.org/PathwayBrowser/#/R-BTA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Bos taurus 30616 R-BTA-5685156 https://reactome.org/PathwayBrowser/#/R-BTA-5685156 ATR phosphorylates RPA2 IEA Bos taurus 30616 R-BTA-5686578 https://reactome.org/PathwayBrowser/#/R-BTA-5686578 Activated ATM phosphorylates ABL1 IEA Bos taurus 30616 R-BTA-5686587 https://reactome.org/PathwayBrowser/#/R-BTA-5686587 ABL1 phosphorylates RAD52 IEA Bos taurus 30616 R-BTA-5686704 https://reactome.org/PathwayBrowser/#/R-BTA-5686704 Activated ATM phosphorylates DCLRE1C IEA Bos taurus 30616 R-BTA-5687086 https://reactome.org/PathwayBrowser/#/R-BTA-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Bos taurus 30616 R-BTA-5687088 https://reactome.org/PathwayBrowser/#/R-BTA-5687088 PKA phosphorylates MAPKAPK5 IEA Bos taurus 30616 R-BTA-5687090 https://reactome.org/PathwayBrowser/#/R-BTA-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Bos taurus 30616 R-BTA-5687094 https://reactome.org/PathwayBrowser/#/R-BTA-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Bos taurus 30616 R-BTA-5687101 https://reactome.org/PathwayBrowser/#/R-BTA-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Bos taurus 30616 R-BTA-5687121 https://reactome.org/PathwayBrowser/#/R-BTA-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Bos taurus 30616 R-BTA-5687183 https://reactome.org/PathwayBrowser/#/R-BTA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Bos taurus 30616 R-BTA-5690250 https://reactome.org/PathwayBrowser/#/R-BTA-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Bos taurus 30616 R-BTA-5690702 https://reactome.org/PathwayBrowser/#/R-BTA-5690702 LYN phosphorylates CD22 IEA Bos taurus 30616 R-BTA-5690996 https://reactome.org/PathwayBrowser/#/R-BTA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Bos taurus 30616 R-BTA-5692462 https://reactome.org/PathwayBrowser/#/R-BTA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Bos taurus 30616 R-BTA-5692480 https://reactome.org/PathwayBrowser/#/R-BTA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Bos taurus 30616 R-BTA-5692755 https://reactome.org/PathwayBrowser/#/R-BTA-5692755 CDK1 phosphorylates MAPK6 IEA Bos taurus 30616 R-BTA-5692775 https://reactome.org/PathwayBrowser/#/R-BTA-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Bos taurus 30616 R-BTA-5692779 https://reactome.org/PathwayBrowser/#/R-BTA-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Bos taurus 30616 R-BTA-5693148 https://reactome.org/PathwayBrowser/#/R-BTA-5693148 BCKDK phosphorylates BCKDH IEA Bos taurus 30616 R-BTA-5693536 https://reactome.org/PathwayBrowser/#/R-BTA-5693536 ATM phosphorylates MDC1 IEA Bos taurus 30616 R-BTA-5693540 https://reactome.org/PathwayBrowser/#/R-BTA-5693540 MRN activates ATM IEA Bos taurus 30616 R-BTA-5693549 https://reactome.org/PathwayBrowser/#/R-BTA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Bos taurus 30616 R-BTA-5693551 https://reactome.org/PathwayBrowser/#/R-BTA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Bos taurus 30616 R-BTA-5693575 https://reactome.org/PathwayBrowser/#/R-BTA-5693575 DNA-PKcs autophosphorylates IEA Bos taurus 30616 R-BTA-5693598 https://reactome.org/PathwayBrowser/#/R-BTA-5693598 ATM phosphorylates NBN IEA Bos taurus 30616 R-BTA-5693609 https://reactome.org/PathwayBrowser/#/R-BTA-5693609 ATM phosphorylates TP53 at S15 IEA Bos taurus 30616 R-BTA-5694425 https://reactome.org/PathwayBrowser/#/R-BTA-5694425 NSF ATPase activity dissociates cis-SNARE IEA Bos taurus 30616 R-BTA-5694441 https://reactome.org/PathwayBrowser/#/R-BTA-5694441 CSNK1D phosphorylates SEC23 IEA Bos taurus 30616 R-BTA-5694494 https://reactome.org/PathwayBrowser/#/R-BTA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Bos taurus 30616 R-BTA-5696004 https://reactome.org/PathwayBrowser/#/R-BTA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Bos taurus 30616 R-BTA-5696007 https://reactome.org/PathwayBrowser/#/R-BTA-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Bos taurus 30616 R-BTA-5696074 https://reactome.org/PathwayBrowser/#/R-BTA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Bos taurus 30616 R-BTA-5696839 https://reactome.org/PathwayBrowser/#/R-BTA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Bos taurus 30616 R-BTA-6782131 https://reactome.org/PathwayBrowser/#/R-BTA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Bos taurus 30616 R-BTA-6784006 https://reactome.org/PathwayBrowser/#/R-BTA-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Bos taurus 30616 R-BTA-6784319 https://reactome.org/PathwayBrowser/#/R-BTA-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Bos taurus 30616 R-BTA-6784324 https://reactome.org/PathwayBrowser/#/R-BTA-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Bos taurus 30616 R-BTA-6786050 https://reactome.org/PathwayBrowser/#/R-BTA-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Bos taurus 30616 R-BTA-6786095 https://reactome.org/PathwayBrowser/#/R-BTA-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Bos taurus 30616 R-BTA-6786096 https://reactome.org/PathwayBrowser/#/R-BTA-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Bos taurus 30616 R-BTA-6786245 https://reactome.org/PathwayBrowser/#/R-BTA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Bos taurus 30616 R-BTA-6787540 https://reactome.org/PathwayBrowser/#/R-BTA-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Bos taurus 30616 R-BTA-6788392 https://reactome.org/PathwayBrowser/#/R-BTA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Bos taurus 30616 R-BTA-6788582 https://reactome.org/PathwayBrowser/#/R-BTA-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Bos taurus 30616 R-BTA-6788798 https://reactome.org/PathwayBrowser/#/R-BTA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 30616 R-BTA-6788810 https://reactome.org/PathwayBrowser/#/R-BTA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 30616 R-BTA-6788855 https://reactome.org/PathwayBrowser/#/R-BTA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Bos taurus 30616 R-BTA-6793661 https://reactome.org/PathwayBrowser/#/R-BTA-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Bos taurus 30616 R-BTA-6797606 https://reactome.org/PathwayBrowser/#/R-BTA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Bos taurus 30616 R-BTA-6798174 https://reactome.org/PathwayBrowser/#/R-BTA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Bos taurus 30616 R-BTA-6798372 https://reactome.org/PathwayBrowser/#/R-BTA-6798372 ATM phosphorylates DYRK2 IEA Bos taurus 30616 R-BTA-6798374 https://reactome.org/PathwayBrowser/#/R-BTA-6798374 DYRK2 phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6799097 https://reactome.org/PathwayBrowser/#/R-BTA-6799097 ATM phosphorylates ZNF420 IEA Bos taurus 30616 R-BTA-6799332 https://reactome.org/PathwayBrowser/#/R-BTA-6799332 ATR phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6799409 https://reactome.org/PathwayBrowser/#/R-BTA-6799409 HIPK2 phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6799495 https://reactome.org/PathwayBrowser/#/R-BTA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Bos taurus 30616 R-BTA-6800490 https://reactome.org/PathwayBrowser/#/R-BTA-6800490 ATM phosphorylates PIDD1 IEA Bos taurus 30616 R-BTA-6801342 https://reactome.org/PathwayBrowser/#/R-BTA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Bos taurus 30616 R-BTA-6801456 https://reactome.org/PathwayBrowser/#/R-BTA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Bos taurus 30616 R-BTA-6801666 https://reactome.org/PathwayBrowser/#/R-BTA-6801666 PLK2 phosphorylates CENPJ IEA Bos taurus 30616 R-BTA-6801675 https://reactome.org/PathwayBrowser/#/R-BTA-6801675 PLK2 phosphorylates NPM1 IEA Bos taurus 30616 R-BTA-6802973 https://reactome.org/PathwayBrowser/#/R-BTA-6802973 PLK3 phosphorylates CDC25C IEA Bos taurus 30616 R-BTA-6803771 https://reactome.org/PathwayBrowser/#/R-BTA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Bos taurus 30616 R-BTA-6804266 https://reactome.org/PathwayBrowser/#/R-BTA-6804266 CHEK2 phosphorylates TTC5 IEA Bos taurus 30616 R-BTA-6804276 https://reactome.org/PathwayBrowser/#/R-BTA-6804276 ATM phosphorylates TTC5 IEA Bos taurus 30616 R-BTA-6804596 https://reactome.org/PathwayBrowser/#/R-BTA-6804596 APAF1:CYCS binds APIP IEA Bos taurus 30616 R-BTA-6804955 https://reactome.org/PathwayBrowser/#/R-BTA-6804955 ATM phosphorylates MDM2 IEA Bos taurus 30616 R-BTA-6805059 https://reactome.org/PathwayBrowser/#/R-BTA-6805059 CK2:FACT phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6805103 https://reactome.org/PathwayBrowser/#/R-BTA-6805103 AURKA phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6805109 https://reactome.org/PathwayBrowser/#/R-BTA-6805109 CDK2 phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6805126 https://reactome.org/PathwayBrowser/#/R-BTA-6805126 AURKB phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6805276 https://reactome.org/PathwayBrowser/#/R-BTA-6805276 CDK5 phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6805285 https://reactome.org/PathwayBrowser/#/R-BTA-6805285 PLK3 phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6805399 https://reactome.org/PathwayBrowser/#/R-BTA-6805399 TAF1 phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6805470 https://reactome.org/PathwayBrowser/#/R-BTA-6805470 AMPK phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6805479 https://reactome.org/PathwayBrowser/#/R-BTA-6805479 TP53RK phosphorylates TP53 IEA Bos taurus 30616 R-BTA-6806877 https://reactome.org/PathwayBrowser/#/R-BTA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Bos taurus 30616 R-BTA-6806967 https://reactome.org/PathwayBrowser/#/R-BTA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Bos taurus 30616 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 30616 R-BTA-6807868 https://reactome.org/PathwayBrowser/#/R-BTA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Bos taurus 30616 R-BTA-6809015 https://reactome.org/PathwayBrowser/#/R-BTA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Bos taurus 30616 R-BTA-6810233 https://reactome.org/PathwayBrowser/#/R-BTA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Bos taurus 30616 R-BTA-6811422 https://reactome.org/PathwayBrowser/#/R-BTA-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Bos taurus 30616 R-BTA-6811454 https://reactome.org/PathwayBrowser/#/R-BTA-6811454 MAPKs phosphorylate PP2A IEA Bos taurus 30616 R-BTA-6811522 https://reactome.org/PathwayBrowser/#/R-BTA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Bos taurus 30616 R-BTA-6814120 https://reactome.org/PathwayBrowser/#/R-BTA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Bos taurus 30616 R-BTA-6814124 https://reactome.org/PathwayBrowser/#/R-BTA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Bos taurus 30616 R-BTA-6814409 https://reactome.org/PathwayBrowser/#/R-BTA-6814409 CK2 phosphorylates PDCL IEA Bos taurus 30616 R-BTA-6814549 https://reactome.org/PathwayBrowser/#/R-BTA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Bos taurus 30616 R-BTA-6814559 https://reactome.org/PathwayBrowser/#/R-BTA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Bos taurus 30616 R-BTA-6814670 https://reactome.org/PathwayBrowser/#/R-BTA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Bos taurus 30616 R-BTA-6814675 https://reactome.org/PathwayBrowser/#/R-BTA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Bos taurus 30616 R-BTA-6814683 https://reactome.org/PathwayBrowser/#/R-BTA-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Bos taurus 30616 R-BTA-68610 https://reactome.org/PathwayBrowser/#/R-BTA-68610 Formation of ORC(2-5) complex IEA Bos taurus 30616 R-BTA-68944 https://reactome.org/PathwayBrowser/#/R-BTA-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Bos taurus 30616 R-BTA-68954 https://reactome.org/PathwayBrowser/#/R-BTA-68954 Mcm2-7 is phosphorylated by DDK IEA Bos taurus 30616 R-BTA-69005 https://reactome.org/PathwayBrowser/#/R-BTA-69005 Cdc6 protein is phosphorylated by CDK IEA Bos taurus 30616 R-BTA-69015 https://reactome.org/PathwayBrowser/#/R-BTA-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Bos taurus 30616 R-BTA-69063 https://reactome.org/PathwayBrowser/#/R-BTA-69063 Loading of PCNA - Sliding Clamp Formation IEA Bos taurus 30616 R-BTA-69195 https://reactome.org/PathwayBrowser/#/R-BTA-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Bos taurus 30616 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 30616 R-BTA-69608 https://reactome.org/PathwayBrowser/#/R-BTA-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Bos taurus 30616 R-BTA-69685 https://reactome.org/PathwayBrowser/#/R-BTA-69685 CHEK2 phosphorylates TP53 IEA Bos taurus 30616 R-BTA-69891 https://reactome.org/PathwayBrowser/#/R-BTA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Bos taurus 30616 R-BTA-70333 https://reactome.org/PathwayBrowser/#/R-BTA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Bos taurus 30616 R-BTA-70349 https://reactome.org/PathwayBrowser/#/R-BTA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Bos taurus 30616 R-BTA-70355 https://reactome.org/PathwayBrowser/#/R-BTA-70355 GALK1 phosphorylates Gal to Gal1P IEA Bos taurus 30616 R-BTA-70420 https://reactome.org/PathwayBrowser/#/R-BTA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Bos taurus 30616 R-BTA-70467 https://reactome.org/PathwayBrowser/#/R-BTA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Bos taurus 30616 R-BTA-70486 https://reactome.org/PathwayBrowser/#/R-BTA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Bos taurus 30616 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 30616 R-BTA-70555 https://reactome.org/PathwayBrowser/#/R-BTA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Bos taurus 30616 R-BTA-70577 https://reactome.org/PathwayBrowser/#/R-BTA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Bos taurus 30616 R-BTA-70599 https://reactome.org/PathwayBrowser/#/R-BTA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Bos taurus 30616 R-BTA-70606 https://reactome.org/PathwayBrowser/#/R-BTA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Bos taurus 30616 R-BTA-70773 https://reactome.org/PathwayBrowser/#/R-BTA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Bos taurus 30616 R-BTA-70967 https://reactome.org/PathwayBrowser/#/R-BTA-70967 IDH3 complex decarboxylates isocitrate IEA Bos taurus 30616 R-BTA-70997 https://reactome.org/PathwayBrowser/#/R-BTA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Bos taurus 30616 R-BTA-71031 https://reactome.org/PathwayBrowser/#/R-BTA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Bos taurus 30616 R-BTA-71401 https://reactome.org/PathwayBrowser/#/R-BTA-71401 OGDH dimer decarboxylates 2-OG IEA Bos taurus 30616 R-BTA-71541 https://reactome.org/PathwayBrowser/#/R-BTA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Bos taurus 30616 R-BTA-71588 https://reactome.org/PathwayBrowser/#/R-BTA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Bos taurus 30616 R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 30616 R-BTA-71735 https://reactome.org/PathwayBrowser/#/R-BTA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Bos taurus 30616 R-BTA-71802 https://reactome.org/PathwayBrowser/#/R-BTA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Bos taurus 30616 R-BTA-71850 https://reactome.org/PathwayBrowser/#/R-BTA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Bos taurus 30616 R-BTA-72180 https://reactome.org/PathwayBrowser/#/R-BTA-72180 Cleavage of mRNA at the 3'-end IEA Bos taurus 30616 R-BTA-72185 https://reactome.org/PathwayBrowser/#/R-BTA-72185 mRNA polyadenylation IEA Bos taurus 30616 R-BTA-72621 https://reactome.org/PathwayBrowser/#/R-BTA-72621 Ribosomal scanning IEA Bos taurus 30616 R-BTA-727819 https://reactome.org/PathwayBrowser/#/R-BTA-727819 TAK1 phosphorylates MKK6 IEA Bos taurus 30616 R-BTA-73548 https://reactome.org/PathwayBrowser/#/R-BTA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Bos taurus 30616 R-BTA-73577 https://reactome.org/PathwayBrowser/#/R-BTA-73577 CAD hexamer transforms L-Gln to CAP IEA Bos taurus 30616 R-BTA-73580 https://reactome.org/PathwayBrowser/#/R-BTA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Bos taurus 30616 R-BTA-73598 https://reactome.org/PathwayBrowser/#/R-BTA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Bos taurus 30616 R-BTA-73599 https://reactome.org/PathwayBrowser/#/R-BTA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Bos taurus 30616 R-BTA-73632 https://reactome.org/PathwayBrowser/#/R-BTA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Bos taurus 30616 R-BTA-73635 https://reactome.org/PathwayBrowser/#/R-BTA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Bos taurus 30616 R-BTA-73647 https://reactome.org/PathwayBrowser/#/R-BTA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Bos taurus 30616 R-BTA-73722 https://reactome.org/PathwayBrowser/#/R-BTA-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Bos taurus 30616 R-BTA-73788 https://reactome.org/PathwayBrowser/#/R-BTA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Bos taurus 30616 R-BTA-73792 https://reactome.org/PathwayBrowser/#/R-BTA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Bos taurus 30616 R-BTA-73805 https://reactome.org/PathwayBrowser/#/R-BTA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Bos taurus 30616 R-BTA-73810 https://reactome.org/PathwayBrowser/#/R-BTA-73810 FGAM + ATP => AIR + ADP + Pi IEA Bos taurus 30616 R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 30616 R-BTA-73814 https://reactome.org/PathwayBrowser/#/R-BTA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Bos taurus 30616 R-BTA-74207 https://reactome.org/PathwayBrowser/#/R-BTA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Bos taurus 30616 R-BTA-74220 https://reactome.org/PathwayBrowser/#/R-BTA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Bos taurus 30616 R-BTA-74618 https://reactome.org/PathwayBrowser/#/R-BTA-74618 PkCa/q phosphorylate Rgs9-1:Gn5b:R9s9bp TAS Bos taurus 30616 R-BTA-74711 https://reactome.org/PathwayBrowser/#/R-BTA-74711 Phosphorylation of IRS IEA Bos taurus 30616 R-BTA-74715 https://reactome.org/PathwayBrowser/#/R-BTA-74715 Autophosphorylation of insulin receptor IEA Bos taurus 30616 R-BTA-74742 https://reactome.org/PathwayBrowser/#/R-BTA-74742 Phosphorylation of SHC1 IEA Bos taurus 30616 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 30616 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 30616 R-BTA-75125 https://reactome.org/PathwayBrowser/#/R-BTA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Bos taurus 30616 R-BTA-75126 https://reactome.org/PathwayBrowser/#/R-BTA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Bos taurus 30616 R-BTA-75809 https://reactome.org/PathwayBrowser/#/R-BTA-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Bos taurus 30616 R-BTA-75848 https://reactome.org/PathwayBrowser/#/R-BTA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Bos taurus 30616 R-BTA-75851 https://reactome.org/PathwayBrowser/#/R-BTA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 30616 R-BTA-75887 https://reactome.org/PathwayBrowser/#/R-BTA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Bos taurus 30616 R-BTA-75949 https://reactome.org/PathwayBrowser/#/R-BTA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Bos taurus 30616 R-BTA-77071 https://reactome.org/PathwayBrowser/#/R-BTA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Bos taurus 30616 R-BTA-844438 https://reactome.org/PathwayBrowser/#/R-BTA-844438 NLRP1 oligomerizes IEA Bos taurus 30616 R-BTA-873918 https://reactome.org/PathwayBrowser/#/R-BTA-873918 Transphosphorylation of JAK1 IEA Bos taurus 30616 R-BTA-873919 https://reactome.org/PathwayBrowser/#/R-BTA-873919 Phosphorylation of JAK2 IEA Bos taurus 30616 R-BTA-873922 https://reactome.org/PathwayBrowser/#/R-BTA-873922 Phosphorylation of STAT1 by JAK kinases IEA Bos taurus 30616 R-BTA-873924 https://reactome.org/PathwayBrowser/#/R-BTA-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Bos taurus 30616 R-BTA-877187 https://reactome.org/PathwayBrowser/#/R-BTA-877187 P2X7 mediates loss of intracellular K+ IEA Bos taurus 30616 R-BTA-877198 https://reactome.org/PathwayBrowser/#/R-BTA-877198 P2X7 mediates membrane pores that include pannexin-1 IEA Bos taurus 30616 R-BTA-879222 https://reactome.org/PathwayBrowser/#/R-BTA-879222 MDP:NLRP1 binds ATP IEA Bos taurus 30616 R-BTA-879907 https://reactome.org/PathwayBrowser/#/R-BTA-879907 Tyrosine kinases phosphorylate the receptor IEA Bos taurus 30616 R-BTA-879909 https://reactome.org/PathwayBrowser/#/R-BTA-879909 Activation of STAT5a/b by JAK2 IEA Bos taurus 30616 R-BTA-879910 https://reactome.org/PathwayBrowser/#/R-BTA-879910 JAK2 is phosphorylated, activated IEA Bos taurus 30616 R-BTA-8847638 https://reactome.org/PathwayBrowser/#/R-BTA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Bos taurus 30616 R-BTA-8847977 https://reactome.org/PathwayBrowser/#/R-BTA-8847977 FRK phosphorylates PTEN IEA Bos taurus 30616 R-BTA-8848005 https://reactome.org/PathwayBrowser/#/R-BTA-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Bos taurus 30616 R-BTA-8848053 https://reactome.org/PathwayBrowser/#/R-BTA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Bos taurus 30616 R-BTA-8848077 https://reactome.org/PathwayBrowser/#/R-BTA-8848077 PTK6 phosphorylates STAP2 IEA Bos taurus 30616 R-BTA-8848124 https://reactome.org/PathwayBrowser/#/R-BTA-8848124 PTK6 phosphorylates STAT3 IEA Bos taurus 30616 R-BTA-8848436 https://reactome.org/PathwayBrowser/#/R-BTA-8848436 PTK6 phosphorylates CDKN1B IEA Bos taurus 30616 R-BTA-8848606 https://reactome.org/PathwayBrowser/#/R-BTA-8848606 PTK6 phosphorylates PXN IEA Bos taurus 30616 R-BTA-8848726 https://reactome.org/PathwayBrowser/#/R-BTA-8848726 PTK6 phosphorylates BCAR1 IEA Bos taurus 30616 R-BTA-8848776 https://reactome.org/PathwayBrowser/#/R-BTA-8848776 PTK6 phosphorylates DOK1 IEA Bos taurus 30616 R-BTA-8848818 https://reactome.org/PathwayBrowser/#/R-BTA-8848818 PTK6 phosphorylates CBL IEA Bos taurus 30616 R-BTA-8848873 https://reactome.org/PathwayBrowser/#/R-BTA-8848873 PTK6 phosphorylates ARAP1 IEA Bos taurus 30616 R-BTA-8848975 https://reactome.org/PathwayBrowser/#/R-BTA-8848975 PTK6 phosphorylates KHDRBS1 IEA Bos taurus 30616 R-BTA-8849032 https://reactome.org/PathwayBrowser/#/R-BTA-8849032 PTK6 phosphorylates KHDRBS2 IEA Bos taurus 30616 R-BTA-8849042 https://reactome.org/PathwayBrowser/#/R-BTA-8849042 PTK6 phosphorylates KHDRBS3 IEA Bos taurus 30616 R-BTA-8849068 https://reactome.org/PathwayBrowser/#/R-BTA-8849068 PTK6 phosphorylates ARHGAP35 IEA Bos taurus 30616 R-BTA-8849102 https://reactome.org/PathwayBrowser/#/R-BTA-8849102 SRMS phosphorylates PTK6 IEA Bos taurus 30616 R-BTA-8849353 https://reactome.org/PathwayBrowser/#/R-BTA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Bos taurus 30616 R-BTA-8849463 https://reactome.org/PathwayBrowser/#/R-BTA-8849463 PTK6 phosphorylates SFPQ IEA Bos taurus 30616 R-BTA-8850945 https://reactome.org/PathwayBrowser/#/R-BTA-8850945 Casein kinase II phosphorylates PTEN IEA Bos taurus 30616 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 30616 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 30616 R-BTA-8851797 https://reactome.org/PathwayBrowser/#/R-BTA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Bos taurus 30616 R-BTA-8851890 https://reactome.org/PathwayBrowser/#/R-BTA-8851890 MET phosphorylates SHC1-2 IEA Bos taurus 30616 R-BTA-8851933 https://reactome.org/PathwayBrowser/#/R-BTA-8851933 MET phosphorylates GAB1 IEA Bos taurus 30616 R-BTA-8852019 https://reactome.org/PathwayBrowser/#/R-BTA-8852019 MET bound PI3K generates PIP3 IEA Bos taurus 30616 R-BTA-8852128 https://reactome.org/PathwayBrowser/#/R-BTA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Bos taurus 30616 R-BTA-8852131 https://reactome.org/PathwayBrowser/#/R-BTA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Bos taurus 30616 R-BTA-8852132 https://reactome.org/PathwayBrowser/#/R-BTA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Bos taurus 30616 R-BTA-8852134 https://reactome.org/PathwayBrowser/#/R-BTA-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Bos taurus 30616 R-BTA-8852306 https://reactome.org/PathwayBrowser/#/R-BTA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Bos taurus 30616 R-BTA-8852317 https://reactome.org/PathwayBrowser/#/R-BTA-8852317 PLK1 phosphorylates GTSE1 IEA Bos taurus 30616 R-BTA-8852552 https://reactome.org/PathwayBrowser/#/R-BTA-8852552 MST1R autophosphorylates IEA Bos taurus 30616 R-BTA-8853419 https://reactome.org/PathwayBrowser/#/R-BTA-8853419 TPX2 promotes AURKA autophosphorylation IEA Bos taurus 30616 R-BTA-8853444 https://reactome.org/PathwayBrowser/#/R-BTA-8853444 AURKA phosphorylates PHLDA1 IEA Bos taurus 30616 R-BTA-8853774 https://reactome.org/PathwayBrowser/#/R-BTA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Bos taurus 30616 R-BTA-8853792 https://reactome.org/PathwayBrowser/#/R-BTA-8853792 RET tyrosine phosphorylation IEA Bos taurus 30616 R-BTA-8854908 https://reactome.org/PathwayBrowser/#/R-BTA-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Bos taurus 30616 R-BTA-8855237 https://reactome.org/PathwayBrowser/#/R-BTA-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Bos taurus 30616 R-BTA-8856813 https://reactome.org/PathwayBrowser/#/R-BTA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Bos taurus 30616 R-BTA-8857555 https://reactome.org/PathwayBrowser/#/R-BTA-8857555 EGFR phosphorylates GPNMB IEA Bos taurus 30616 R-BTA-8857577 https://reactome.org/PathwayBrowser/#/R-BTA-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Bos taurus 30616 R-BTA-8857583 https://reactome.org/PathwayBrowser/#/R-BTA-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Bos taurus 30616 R-BTA-8857925 https://reactome.org/PathwayBrowser/#/R-BTA-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Bos taurus 30616 R-BTA-8865774 https://reactome.org/PathwayBrowser/#/R-BTA-8865774 TTLLs polyglutamylate tubulin IEA Bos taurus 30616 R-BTA-8866268 https://reactome.org/PathwayBrowser/#/R-BTA-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Bos taurus 30616 R-BTA-8866405 https://reactome.org/PathwayBrowser/#/R-BTA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 30616 R-BTA-8866542 https://reactome.org/PathwayBrowser/#/R-BTA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Bos taurus 30616 R-BTA-8867041 https://reactome.org/PathwayBrowser/#/R-BTA-8867041 EGFR phosphorylates EPS15 IEA Bos taurus 30616 R-BTA-8867370 https://reactome.org/PathwayBrowser/#/R-BTA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Bos taurus 30616 R-BTA-8868066 https://reactome.org/PathwayBrowser/#/R-BTA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Bos taurus 30616 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 30616 R-BTA-8868118 https://reactome.org/PathwayBrowser/#/R-BTA-8868118 MAPK12 phosphorylates PTPN3 IEA Bos taurus 30616 R-BTA-8868230 https://reactome.org/PathwayBrowser/#/R-BTA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Bos taurus 30616 R-BTA-8868236 https://reactome.org/PathwayBrowser/#/R-BTA-8868236 BAR domain proteins recruit dynamin IEA Bos taurus 30616 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 30616 R-BTA-8868651 https://reactome.org/PathwayBrowser/#/R-BTA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Bos taurus 30616 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 30616 R-BTA-8868659 https://reactome.org/PathwayBrowser/#/R-BTA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Bos taurus 30616 R-BTA-8868660 https://reactome.org/PathwayBrowser/#/R-BTA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Bos taurus 30616 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 30616 R-BTA-8869606 https://reactome.org/PathwayBrowser/#/R-BTA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Bos taurus 30616 R-BTA-8869607 https://reactome.org/PathwayBrowser/#/R-BTA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Bos taurus 30616 R-BTA-8869627 https://reactome.org/PathwayBrowser/#/R-BTA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Bos taurus 30616 R-BTA-8869633 https://reactome.org/PathwayBrowser/#/R-BTA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Bos taurus 30616 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 30616 R-BTA-8871194 https://reactome.org/PathwayBrowser/#/R-BTA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Bos taurus 30616 R-BTA-8871373 https://reactome.org/PathwayBrowser/#/R-BTA-8871373 BMX phosphorylates RUFY1 IEA Bos taurus 30616 R-BTA-8873929 https://reactome.org/PathwayBrowser/#/R-BTA-8873929 Casein kinase II phosphorylates STARD10 IEA Bos taurus 30616 R-BTA-8874078 https://reactome.org/PathwayBrowser/#/R-BTA-8874078 PTK2 autophosphorylates IEA Bos taurus 30616 R-BTA-8874080 https://reactome.org/PathwayBrowser/#/R-BTA-8874080 SRC phosphorylates PTK2 IEA Bos taurus 30616 R-BTA-8874082 https://reactome.org/PathwayBrowser/#/R-BTA-8874082 MET phosphorylates PTK2 IEA Bos taurus 30616 R-BTA-8875071 https://reactome.org/PathwayBrowser/#/R-BTA-8875071 ACSS3 ligates CoA to CH3COO- IEA Bos taurus 30616 R-BTA-8875451 https://reactome.org/PathwayBrowser/#/R-BTA-8875451 MET phosphorylates CBL IEA Bos taurus 30616 R-BTA-8875817 https://reactome.org/PathwayBrowser/#/R-BTA-8875817 MET phosphorylates STAT3 IEA Bos taurus 30616 R-BTA-8876446 https://reactome.org/PathwayBrowser/#/R-BTA-8876446 p-ULK1 phosphorylates DENND3 IEA Bos taurus 30616 R-BTA-8876889 https://reactome.org/PathwayBrowser/#/R-BTA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 30616 R-BTA-8877691 https://reactome.org/PathwayBrowser/#/R-BTA-8877691 MAP2K6 phosphorylates PIP4K2B IEA Bos taurus 30616 R-BTA-8878050 https://reactome.org/PathwayBrowser/#/R-BTA-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Bos taurus 30616 R-BTA-8878054 https://reactome.org/PathwayBrowser/#/R-BTA-8878054 HIPK2 phosphorylates RUNX1 IEA Bos taurus 30616 R-BTA-8931653 https://reactome.org/PathwayBrowser/#/R-BTA-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Bos taurus 30616 R-BTA-8937807 https://reactome.org/PathwayBrowser/#/R-BTA-8937807 SRC phosphorylates RUNX3 IEA Bos taurus 30616 R-BTA-8939204 https://reactome.org/PathwayBrowser/#/R-BTA-8939204 ESTG binds ESR1:chaperone complex IEA Bos taurus 30616 R-BTA-8939959 https://reactome.org/PathwayBrowser/#/R-BTA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Bos taurus 30616 R-BTA-8940100 https://reactome.org/PathwayBrowser/#/R-BTA-8940100 CDK1 phosphorylates VCPIP1 IEA Bos taurus 30616 R-BTA-8942575 https://reactome.org/PathwayBrowser/#/R-BTA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Bos taurus 30616 R-BTA-8942607 https://reactome.org/PathwayBrowser/#/R-BTA-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Bos taurus 30616 R-BTA-8942836 https://reactome.org/PathwayBrowser/#/R-BTA-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Bos taurus 30616 R-BTA-8944454 https://reactome.org/PathwayBrowser/#/R-BTA-8944454 mTORC1 phosphorylates MAF1 IEA Bos taurus 30616 R-BTA-8948039 https://reactome.org/PathwayBrowser/#/R-BTA-8948039 FUNDC1 is phosphorylated by CK2 IEA Bos taurus 30616 R-BTA-8948143 https://reactome.org/PathwayBrowser/#/R-BTA-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Bos taurus 30616 R-BTA-8948146 https://reactome.org/PathwayBrowser/#/R-BTA-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Bos taurus 30616 R-BTA-8950269 https://reactome.org/PathwayBrowser/#/R-BTA-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Bos taurus 30616 R-BTA-8950340 https://reactome.org/PathwayBrowser/#/R-BTA-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Bos taurus 30616 R-BTA-8950405 https://reactome.org/PathwayBrowser/#/R-BTA-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Bos taurus 30616 R-BTA-8950423 https://reactome.org/PathwayBrowser/#/R-BTA-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Bos taurus 30616 R-BTA-8950453 https://reactome.org/PathwayBrowser/#/R-BTA-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Bos taurus 30616 R-BTA-8950485 https://reactome.org/PathwayBrowser/#/R-BTA-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Bos taurus 30616 R-BTA-8950537 https://reactome.org/PathwayBrowser/#/R-BTA-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Bos taurus 30616 R-BTA-8950757 https://reactome.org/PathwayBrowser/#/R-BTA-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Bos taurus 30616 R-BTA-8951648 https://reactome.org/PathwayBrowser/#/R-BTA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Bos taurus 30616 R-BTA-8951656 https://reactome.org/PathwayBrowser/#/R-BTA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Bos taurus 30616 R-BTA-8952289 https://reactome.org/PathwayBrowser/#/R-BTA-8952289 FAM20C phosphorylates FAM20C substrates IEA Bos taurus 30616 R-BTA-8954327 https://reactome.org/PathwayBrowser/#/R-BTA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Bos taurus 30616 R-BTA-8955030 https://reactome.org/PathwayBrowser/#/R-BTA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Bos taurus 30616 R-BTA-8955724 https://reactome.org/PathwayBrowser/#/R-BTA-8955724 TTL ligates L-Tyr to the carboxy terminus of alpha-tubulin TAS Bos taurus 30616 R-BTA-8955844 https://reactome.org/PathwayBrowser/#/R-BTA-8955844 RBKS phosphorylates ribose to R5P IEA Bos taurus 30616 R-BTA-8956659 https://reactome.org/PathwayBrowser/#/R-BTA-8956659 ABL1 phosphorylates YAP1 IEA Bos taurus 30616 R-BTA-8959719 https://reactome.org/PathwayBrowser/#/R-BTA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Bos taurus 30616 R-BTA-8964242 https://reactome.org/PathwayBrowser/#/R-BTA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Bos taurus 30616 R-BTA-8982163 https://reactome.org/PathwayBrowser/#/R-BTA-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Bos taurus 30616 R-BTA-8983059 https://reactome.org/PathwayBrowser/#/R-BTA-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Bos taurus 30616 R-BTA-8983063 https://reactome.org/PathwayBrowser/#/R-BTA-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Bos taurus 30616 R-BTA-8983300 https://reactome.org/PathwayBrowser/#/R-BTA-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Bos taurus 30616 R-BTA-8983371 https://reactome.org/PathwayBrowser/#/R-BTA-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Bos taurus 30616 R-BTA-8983834 https://reactome.org/PathwayBrowser/#/R-BTA-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Bos taurus 30616 R-BTA-8983835 https://reactome.org/PathwayBrowser/#/R-BTA-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Bos taurus 30616 R-BTA-8983870 https://reactome.org/PathwayBrowser/#/R-BTA-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Bos taurus 30616 R-BTA-8983872 https://reactome.org/PathwayBrowser/#/R-BTA-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Bos taurus 30616 R-BTA-8984012 https://reactome.org/PathwayBrowser/#/R-BTA-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Bos taurus 30616 R-BTA-8984014 https://reactome.org/PathwayBrowser/#/R-BTA-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Bos taurus 30616 R-BTA-8985914 https://reactome.org/PathwayBrowser/#/R-BTA-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Bos taurus 30616 R-BTA-8985973 https://reactome.org/PathwayBrowser/#/R-BTA-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Bos taurus 30616 R-BTA-8985988 https://reactome.org/PathwayBrowser/#/R-BTA-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Bos taurus 30616 R-BTA-8986985 https://reactome.org/PathwayBrowser/#/R-BTA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Bos taurus 30616 R-BTA-8986994 https://reactome.org/PathwayBrowser/#/R-BTA-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Bos taurus 30616 R-BTA-8986995 https://reactome.org/PathwayBrowser/#/R-BTA-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Bos taurus 30616 R-BTA-8987012 https://reactome.org/PathwayBrowser/#/R-BTA-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Bos taurus 30616 R-BTA-8987040 https://reactome.org/PathwayBrowser/#/R-BTA-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Bos taurus 30616 R-BTA-8987042 https://reactome.org/PathwayBrowser/#/R-BTA-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Bos taurus 30616 R-BTA-8987070 https://reactome.org/PathwayBrowser/#/R-BTA-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Bos taurus 30616 R-BTA-8987084 https://reactome.org/PathwayBrowser/#/R-BTA-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Bos taurus 30616 R-BTA-8987096 https://reactome.org/PathwayBrowser/#/R-BTA-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Bos taurus 30616 R-BTA-8987129 https://reactome.org/PathwayBrowser/#/R-BTA-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Bos taurus 30616 R-BTA-8987141 https://reactome.org/PathwayBrowser/#/R-BTA-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Bos taurus 30616 R-BTA-8987150 https://reactome.org/PathwayBrowser/#/R-BTA-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Bos taurus 30616 R-BTA-8987179 https://reactome.org/PathwayBrowser/#/R-BTA-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Bos taurus 30616 R-BTA-8987202 https://reactome.org/PathwayBrowser/#/R-BTA-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Bos taurus 30616 R-BTA-8987255 https://reactome.org/PathwayBrowser/#/R-BTA-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Bos taurus 30616 R-BTA-9006850 https://reactome.org/PathwayBrowser/#/R-BTA-9006850 IL21 receptor JAK phosphorylation IEA Bos taurus 30616 R-BTA-9006870 https://reactome.org/PathwayBrowser/#/R-BTA-9006870 IL21 receptor STAT phosphorylation IEA Bos taurus 30616 R-BTA-9008043 https://reactome.org/PathwayBrowser/#/R-BTA-9008043 MAPK8 phosphorylation IEA Bos taurus 30616 R-BTA-9008412 https://reactome.org/PathwayBrowser/#/R-BTA-9008412 CDK4 phosphorylates RUNX2 IEA Bos taurus 30616 R-BTA-9008684 https://reactome.org/PathwayBrowser/#/R-BTA-9008684 TBK1 phosphorylation IEA Bos taurus 30616 R-BTA-9009072 https://reactome.org/PathwayBrowser/#/R-BTA-9009072 STAT3 phosphorylation IEA Bos taurus 30616 R-BTA-9009282 https://reactome.org/PathwayBrowser/#/R-BTA-9009282 CDK1 phosphorylates RUNX2 IEA Bos taurus 30616 R-BTA-9009936 https://reactome.org/PathwayBrowser/#/R-BTA-9009936 RNASEL cleaves cellular ssRNA IEA Bos taurus 30616 R-BTA-9009950 https://reactome.org/PathwayBrowser/#/R-BTA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Bos taurus 30616 R-BTA-9012268 https://reactome.org/PathwayBrowser/#/R-BTA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Bos taurus 30616 R-BTA-9012319 https://reactome.org/PathwayBrowser/#/R-BTA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Bos taurus 30616 R-BTA-9014741 https://reactome.org/PathwayBrowser/#/R-BTA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Bos taurus 30616 R-BTA-9014766 https://reactome.org/PathwayBrowser/#/R-BTA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Bos taurus 30616 R-BTA-9021357 https://reactome.org/PathwayBrowser/#/R-BTA-9021357 PRKCI phosphorylates ELF3 IEA Bos taurus 30616 R-BTA-9021609 https://reactome.org/PathwayBrowser/#/R-BTA-9021609 ESR-associated SRC autophosphorylates IEA Bos taurus 30616 R-BTA-9021627 https://reactome.org/PathwayBrowser/#/R-BTA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 30616 R-BTA-9022314 https://reactome.org/PathwayBrowser/#/R-BTA-9022314 HIPK2 phosphorylates MECP2 IEA Bos taurus 30616 R-BTA-9027272 https://reactome.org/PathwayBrowser/#/R-BTA-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Bos taurus 30616 R-BTA-9027273 https://reactome.org/PathwayBrowser/#/R-BTA-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Bos taurus 30616 R-BTA-9033499 https://reactome.org/PathwayBrowser/#/R-BTA-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Bos taurus 30616 R-BTA-9034714 https://reactome.org/PathwayBrowser/#/R-BTA-9034714 NTRK3 dimers trans-autophosphorylate IEA Bos taurus 30616 R-BTA-9038161 https://reactome.org/PathwayBrowser/#/R-BTA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Bos taurus 30616 R-BTA-909552 https://reactome.org/PathwayBrowser/#/R-BTA-909552 Phosphorylation of STAT1 at Ser727 IEA Bos taurus 30616 R-BTA-909718 https://reactome.org/PathwayBrowser/#/R-BTA-909718 Formation of p-STAT1 homodimer IEA Bos taurus 30616 R-BTA-909729 https://reactome.org/PathwayBrowser/#/R-BTA-909729 Activation of JAK kinases IEA Bos taurus 30616 R-BTA-909730 https://reactome.org/PathwayBrowser/#/R-BTA-909730 Phosphorylation of INFAR1 by TYK2 IEA Bos taurus 30616 R-BTA-909732 https://reactome.org/PathwayBrowser/#/R-BTA-909732 Phosphorylation of STAT2 IEA Bos taurus 30616 R-BTA-912527 https://reactome.org/PathwayBrowser/#/R-BTA-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Bos taurus 30616 R-BTA-913996 https://reactome.org/PathwayBrowser/#/R-BTA-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Bos taurus 30616 R-BTA-917693 https://reactome.org/PathwayBrowser/#/R-BTA-917693 ESCRT Disassembly IEA Bos taurus 30616 R-BTA-917841 https://reactome.org/PathwayBrowser/#/R-BTA-917841 Acidification of Tf:TfR1 containing endosome IEA Bos taurus 30616 R-BTA-917979 https://reactome.org/PathwayBrowser/#/R-BTA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-927889 https://reactome.org/PathwayBrowser/#/R-BTA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Bos taurus 30616 R-BTA-934559 https://reactome.org/PathwayBrowser/#/R-BTA-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Bos taurus 30616 R-BTA-936883 https://reactome.org/PathwayBrowser/#/R-BTA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Bos taurus 30616 R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 30616 R-BTA-936951 https://reactome.org/PathwayBrowser/#/R-BTA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Bos taurus 30616 R-BTA-936991 https://reactome.org/PathwayBrowser/#/R-BTA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Bos taurus 30616 R-BTA-937034 https://reactome.org/PathwayBrowser/#/R-BTA-937034 IRAK1 phosphorylates Pellino IEA Bos taurus 30616 R-BTA-937311 https://reactome.org/PathwayBrowser/#/R-BTA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Bos taurus 30616 R-BTA-939763 https://reactome.org/PathwayBrowser/#/R-BTA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Bos taurus 30616 R-BTA-947531 https://reactome.org/PathwayBrowser/#/R-BTA-947531 Molybdenum ion transfer onto molybdopterin IEA Bos taurus 30616 R-BTA-947591 https://reactome.org/PathwayBrowser/#/R-BTA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Bos taurus 30616 R-BTA-9603420 https://reactome.org/PathwayBrowser/#/R-BTA-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Bos taurus 30616 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 30616 R-BTA-9606884 https://reactome.org/PathwayBrowser/#/R-BTA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Bos taurus 30616 R-BTA-9610153 https://reactome.org/PathwayBrowser/#/R-BTA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Bos taurus 30616 R-BTA-9610156 https://reactome.org/PathwayBrowser/#/R-BTA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Bos taurus 30616 R-BTA-9610163 https://reactome.org/PathwayBrowser/#/R-BTA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Bos taurus 30616 R-BTA-9613494 https://reactome.org/PathwayBrowser/#/R-BTA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Bos taurus 30616 R-BTA-9619355 https://reactome.org/PathwayBrowser/#/R-BTA-9619355 CaMKK autophosphorylates in the cytosol IEA Bos taurus 30616 R-BTA-9624800 https://reactome.org/PathwayBrowser/#/R-BTA-9624800 CDK1 phosphorylates LBR IEA Bos taurus 30616 R-BTA-9625487 https://reactome.org/PathwayBrowser/#/R-BTA-9625487 PTK2 autophosphorylates downstream of EGFR IEA Bos taurus 30616 R-BTA-9626817 https://reactome.org/PathwayBrowser/#/R-BTA-9626817 PKC phosphorylates NCF1 IEA Bos taurus 30616 R-BTA-9626832 https://reactome.org/PathwayBrowser/#/R-BTA-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Bos taurus 30616 R-BTA-9626880 https://reactome.org/PathwayBrowser/#/R-BTA-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Bos taurus 30616 R-BTA-9627056 https://reactome.org/PathwayBrowser/#/R-BTA-9627056 Procaspase 9 forms dimer IEA Bos taurus 30616 R-BTA-9627089 https://reactome.org/PathwayBrowser/#/R-BTA-9627089 CASP9 is phosphorylated at T412 IEA Bos taurus 30616 R-BTA-9632858 https://reactome.org/PathwayBrowser/#/R-BTA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Bos taurus 30616 R-BTA-9632868 https://reactome.org/PathwayBrowser/#/R-BTA-9632868 CDKN1B is phosphorylated in response to estrogen IEA Bos taurus 30616 R-BTA-9634702 https://reactome.org/PathwayBrowser/#/R-BTA-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Bos taurus 30616 R-BTA-9645442 https://reactome.org/PathwayBrowser/#/R-BTA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Bos taurus 30616 R-BTA-9645535 https://reactome.org/PathwayBrowser/#/R-BTA-9645535 ALPK1 phosphorylates TIFA IEA Bos taurus 30616 R-BTA-9648089 https://reactome.org/PathwayBrowser/#/R-BTA-9648089 NEK6 and NEK7 phosphorylate EML4 IEA Bos taurus 30616 R-BTA-964958 https://reactome.org/PathwayBrowser/#/R-BTA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Bos taurus 30616 R-BTA-964962 https://reactome.org/PathwayBrowser/#/R-BTA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Bos taurus 30616 R-BTA-964970 https://reactome.org/PathwayBrowser/#/R-BTA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Bos taurus 30616 R-BTA-9653503 https://reactome.org/PathwayBrowser/#/R-BTA-9653503 KRAS4B is phosphorylated on serine 181 IEA Bos taurus 30616 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 30616 R-BTA-9661417 https://reactome.org/PathwayBrowser/#/R-BTA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-9668419 https://reactome.org/PathwayBrowser/#/R-BTA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Bos taurus 30616 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 30616 R-BTA-9684118 https://reactome.org/PathwayBrowser/#/R-BTA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Bos taurus 30616 R-BTA-9686521 https://reactome.org/PathwayBrowser/#/R-BTA-9686521 CDK2:CCNA phosphorylates TERF2 IEA Bos taurus 30616 R-BTA-9687625 https://reactome.org/PathwayBrowser/#/R-BTA-9687625 ATP binds MLKL IEA Bos taurus 30616 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 30616 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 30616 R-BTA-9699578 https://reactome.org/PathwayBrowser/#/R-BTA-9699578 Active FLT3 phosphorylates CDKN1B IEA Bos taurus 30616 R-BTA-9700168 https://reactome.org/PathwayBrowser/#/R-BTA-9700168 Active ALK phosphorylates IRS1 IEA Bos taurus 30616 R-BTA-9700171 https://reactome.org/PathwayBrowser/#/R-BTA-9700171 Active ALK phosphorylates PLCG1 IEA Bos taurus 30616 R-BTA-9700175 https://reactome.org/PathwayBrowser/#/R-BTA-9700175 Active ALK phosphorylates SHC1 IEA Bos taurus 30616 R-BTA-9701488 https://reactome.org/PathwayBrowser/#/R-BTA-9701488 Active ALK phosphorylates JAK3 IEA Bos taurus 30616 R-BTA-9705925 https://reactome.org/PathwayBrowser/#/R-BTA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Bos taurus 30616 R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 30616 R-BTA-9706344 https://reactome.org/PathwayBrowser/#/R-BTA-9706344 FLT3 phosphorylates GRB10 IEA Bos taurus 30616 R-BTA-9706350 https://reactome.org/PathwayBrowser/#/R-BTA-9706350 FLT3 phosphorylates CBL IEA Bos taurus 30616 R-BTA-9706390 https://reactome.org/PathwayBrowser/#/R-BTA-9706390 RHOBTB3 binds interacting proteins at trans-Golgi network IEA Bos taurus 30616 R-BTA-9706393 https://reactome.org/PathwayBrowser/#/R-BTA-9706393 RHOBTB3 binds ATP IEA Bos taurus 30616 R-BTA-9706399 https://reactome.org/PathwayBrowser/#/R-BTA-9706399 RHOBTB3 hydrolyzes ATP IEA Bos taurus 30616 R-BTA-9706837 https://reactome.org/PathwayBrowser/#/R-BTA-9706837 AR binds AR antagonists IEA Bos taurus 30616 R-BTA-9709547 https://reactome.org/PathwayBrowser/#/R-BTA-9709547 ESTG binds ESR2:chaperone complex IEA Bos taurus 30616 R-BTA-9716913 https://reactome.org/PathwayBrowser/#/R-BTA-9716913 ESR1 binds ESR1 antagonists IEA Bos taurus 30616 R-BTA-9716947 https://reactome.org/PathwayBrowser/#/R-BTA-9716947 ESR1 binds ESR1 agonists IEA Bos taurus 30616 R-BTA-9725855 https://reactome.org/PathwayBrowser/#/R-BTA-9725855 NR3C2 binds NR3C2 antagonists IEA Bos taurus 30616 R-BTA-9725885 https://reactome.org/PathwayBrowser/#/R-BTA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Bos taurus 30616 R-BTA-9726509 https://reactome.org/PathwayBrowser/#/R-BTA-9726509 NR3C2 binds fludrocortisone IEA Bos taurus 30616 R-BTA-9726580 https://reactome.org/PathwayBrowser/#/R-BTA-9726580 PGR binds PGR agonists IEA Bos taurus 30616 R-BTA-9726621 https://reactome.org/PathwayBrowser/#/R-BTA-9726621 PGR binds PGR antagonists IEA Bos taurus 30616 R-BTA-9727198 https://reactome.org/PathwayBrowser/#/R-BTA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Bos taurus 30616 R-BTA-9731111 https://reactome.org/PathwayBrowser/#/R-BTA-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Bos taurus 30616 R-BTA-9732738 https://reactome.org/PathwayBrowser/#/R-BTA-9732738 JAK1-mediated phosphorylation of RAF1 IEA Bos taurus 30616 R-BTA-9732753 https://reactome.org/PathwayBrowser/#/R-BTA-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Bos taurus 30616 R-BTA-9734535 https://reactome.org/PathwayBrowser/#/R-BTA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Bos taurus 30616 R-BTA-9734547 https://reactome.org/PathwayBrowser/#/R-BTA-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Bos taurus 30616 R-BTA-9734687 https://reactome.org/PathwayBrowser/#/R-BTA-9734687 ORC6 is phosphorylated on T195 IEA Bos taurus 30616 R-BTA-9748949 https://reactome.org/PathwayBrowser/#/R-BTA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Bos taurus 30616 R-BTA-9748957 https://reactome.org/PathwayBrowser/#/R-BTA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Bos taurus 30616 R-BTA-9748963 https://reactome.org/PathwayBrowser/#/R-BTA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Bos taurus 30616 R-BTA-9748969 https://reactome.org/PathwayBrowser/#/R-BTA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Bos taurus 30616 R-BTA-9748999 https://reactome.org/PathwayBrowser/#/R-BTA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Bos taurus 30616 R-BTA-9749971 https://reactome.org/PathwayBrowser/#/R-BTA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Bos taurus 30616 R-BTA-9750546 https://reactome.org/PathwayBrowser/#/R-BTA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-9750617 https://reactome.org/PathwayBrowser/#/R-BTA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-9750656 https://reactome.org/PathwayBrowser/#/R-BTA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Bos taurus 30616 R-BTA-975103 https://reactome.org/PathwayBrowser/#/R-BTA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Bos taurus 30616 R-BTA-975139 https://reactome.org/PathwayBrowser/#/R-BTA-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Bos taurus 30616 R-BTA-9753278 https://reactome.org/PathwayBrowser/#/R-BTA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 30616 R-BTA-9753283 https://reactome.org/PathwayBrowser/#/R-BTA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 30616 R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 30616 R-BTA-9754974 https://reactome.org/PathwayBrowser/#/R-BTA-9754974 ADK phosphorylates RBV IEA Bos taurus 30616 R-BTA-9755013 https://reactome.org/PathwayBrowser/#/R-BTA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Bos taurus 30616 R-BTA-9759206 https://reactome.org/PathwayBrowser/#/R-BTA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Bos taurus 30616 R-BTA-9759454 https://reactome.org/PathwayBrowser/#/R-BTA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Bos taurus 30616 R-BTA-9759461 https://reactome.org/PathwayBrowser/#/R-BTA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Bos taurus 30616 R-BTA-9760094 https://reactome.org/PathwayBrowser/#/R-BTA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Bos taurus 30616 R-BTA-9762094 https://reactome.org/PathwayBrowser/#/R-BTA-9762094 GSK3B phosphorylates p-NFE2L2 IEA Bos taurus 30616 R-BTA-9770141 https://reactome.org/PathwayBrowser/#/R-BTA-9770141 Formation of the Spliceosomal C* complex IEA Bos taurus 30616 R-BTA-9770145 https://reactome.org/PathwayBrowser/#/R-BTA-9770145 Formation of the Spliceosomal Bact complex IEA Bos taurus 30616 R-BTA-9773803 https://reactome.org/PathwayBrowser/#/R-BTA-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Bos taurus 30616 R-BTA-9794120 https://reactome.org/PathwayBrowser/#/R-BTA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Bos taurus 30616 R-BTA-9794572 https://reactome.org/PathwayBrowser/#/R-BTA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Bos taurus 30616 R-BTA-9796053 https://reactome.org/PathwayBrowser/#/R-BTA-9796053 PRKCI phosphorylates NFE2L2 IEA Bos taurus 30616 R-BTA-9796067 https://reactome.org/PathwayBrowser/#/R-BTA-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Bos taurus 30616 R-BTA-9815501 https://reactome.org/PathwayBrowser/#/R-BTA-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 IEA Bos taurus 30616 R-BTA-9817397 https://reactome.org/PathwayBrowser/#/R-BTA-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Bos taurus 30616 R-BTA-9818789 https://reactome.org/PathwayBrowser/#/R-BTA-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Bos taurus 30616 R-BTA-9819106 https://reactome.org/PathwayBrowser/#/R-BTA-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Bos taurus 30616 R-BTA-9823906 https://reactome.org/PathwayBrowser/#/R-BTA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Bos taurus 30616 R-BTA-9824882 https://reactome.org/PathwayBrowser/#/R-BTA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Bos taurus 30616 R-BTA-9824977 https://reactome.org/PathwayBrowser/#/R-BTA-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Bos taurus 30616 R-BTA-9824994 https://reactome.org/PathwayBrowser/#/R-BTA-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Bos taurus 30616 R-BTA-9824995 https://reactome.org/PathwayBrowser/#/R-BTA-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Bos taurus 30616 R-BTA-9824999 https://reactome.org/PathwayBrowser/#/R-BTA-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Bos taurus 30616 R-BTA-9825759 https://reactome.org/PathwayBrowser/#/R-BTA-9825759 MAPK-dependent phosphorylation of KARS IEA Bos taurus 30616 R-BTA-983140 https://reactome.org/PathwayBrowser/#/R-BTA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Bos taurus 30616 R-BTA-983144 https://reactome.org/PathwayBrowser/#/R-BTA-983144 Transport of Antigen peptide in to ER IEA Bos taurus 30616 R-BTA-983153 https://reactome.org/PathwayBrowser/#/R-BTA-983153 E1 mediated ubiquitin activation IEA Bos taurus 30616 R-BTA-983156 https://reactome.org/PathwayBrowser/#/R-BTA-983156 Polyubiquitination of substrate IEA Bos taurus 30616 R-BTA-983259 https://reactome.org/PathwayBrowser/#/R-BTA-983259 Kinesins move along microtubules consuming ATP IEA Bos taurus 30616 R-BTA-9833973 https://reactome.org/PathwayBrowser/#/R-BTA-9833973 ISGylation of PKR IEA Bos taurus 30616 R-BTA-9836159 https://reactome.org/PathwayBrowser/#/R-BTA-9836159 p-PKR dimer phosphorylates DHX9 IEA Bos taurus 30616 R-BTA-9836184 https://reactome.org/PathwayBrowser/#/R-BTA-9836184 p-PKR dimer phosphorylates CDK1 IEA Bos taurus 30616 R-BTA-9836322 https://reactome.org/PathwayBrowser/#/R-BTA-9836322 p-PKR dimer phosphorylates MKK6 IEA Bos taurus 30616 R-BTA-9836362 https://reactome.org/PathwayBrowser/#/R-BTA-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Bos taurus 30616 R-BTA-9836383 https://reactome.org/PathwayBrowser/#/R-BTA-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Bos taurus 30616 R-BTA-9836435 https://reactome.org/PathwayBrowser/#/R-BTA-9836435 p-PKR dimer phosphorylates SNCA IEA Bos taurus 30616 R-BTA-9836515 https://reactome.org/PathwayBrowser/#/R-BTA-9836515 p-PKR dimer phosphorylates PTPN2 IEA Bos taurus 30616 R-BTA-9836617 https://reactome.org/PathwayBrowser/#/R-BTA-9836617 p-PKR dimer phosphorylates SPHK1 IEA Bos taurus 30616 R-BTA-9836664 https://reactome.org/PathwayBrowser/#/R-BTA-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Bos taurus 30616 R-BTA-983703 https://reactome.org/PathwayBrowser/#/R-BTA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Bos taurus 30616 R-BTA-983707 https://reactome.org/PathwayBrowser/#/R-BTA-983707 SYK autophosphorylates at the activated BCR IEA Bos taurus 30616 R-BTA-9837337 https://reactome.org/PathwayBrowser/#/R-BTA-9837337 DCAKD phosphorylates DP-CoA IEA Bos taurus 30616 R-BTA-9838004 https://reactome.org/PathwayBrowser/#/R-BTA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Bos taurus 30616 R-BTA-9838081 https://reactome.org/PathwayBrowser/#/R-BTA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Bos taurus 30616 R-BTA-9838289 https://reactome.org/PathwayBrowser/#/R-BTA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Bos taurus 30616 R-BTA-9838321 https://reactome.org/PathwayBrowser/#/R-BTA-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Bos taurus 30616 R-BTA-9839059 https://reactome.org/PathwayBrowser/#/R-BTA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Bos taurus 30616 R-BTA-9839105 https://reactome.org/PathwayBrowser/#/R-BTA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Bos taurus 30616 R-BTA-9839113 https://reactome.org/PathwayBrowser/#/R-BTA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Bos taurus 30616 R-BTA-9840564 https://reactome.org/PathwayBrowser/#/R-BTA-9840564 OMA1 hydrolyzes YME1L1 IEA Bos taurus 30616 R-BTA-9843721 https://reactome.org/PathwayBrowser/#/R-BTA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Bos taurus 30616 R-BTA-9851972 https://reactome.org/PathwayBrowser/#/R-BTA-9851972 PLK1 phosphorylates FIRRM at S43 IEA Bos taurus 30616 R-BTA-9853369 https://reactome.org/PathwayBrowser/#/R-BTA-9853369 PLK1 phosphorylates FIRMM at S744 IEA Bos taurus 30616 R-BTA-9861642 https://reactome.org/PathwayBrowser/#/R-BTA-9861642 NEK1 phosphorylates ME1 IEA Bos taurus 30616 R-BTA-994137 https://reactome.org/PathwayBrowser/#/R-BTA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Bos taurus 30616 R-BTA-994140 https://reactome.org/PathwayBrowser/#/R-BTA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Bos taurus 30616 R-CEL-109624 https://reactome.org/PathwayBrowser/#/R-CEL-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Caenorhabditis elegans 30616 R-CEL-109702 https://reactome.org/PathwayBrowser/#/R-CEL-109702 PDPK1 phosphorylates AKT2 IEA Caenorhabditis elegans 30616 R-CEL-109860 https://reactome.org/PathwayBrowser/#/R-CEL-109860 MAP2K1 phosphorylates MAPK3 IEA Caenorhabditis elegans 30616 R-CEL-109862 https://reactome.org/PathwayBrowser/#/R-CEL-109862 MAP2K2 phosphorylates MAPK1 IEA Caenorhabditis elegans 30616 R-CEL-109903 https://reactome.org/PathwayBrowser/#/R-CEL-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Caenorhabditis elegans 30616 R-CEL-110133 https://reactome.org/PathwayBrowser/#/R-CEL-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Caenorhabditis elegans 30616 R-CEL-110137 https://reactome.org/PathwayBrowser/#/R-CEL-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Caenorhabditis elegans 30616 R-CEL-110138 https://reactome.org/PathwayBrowser/#/R-CEL-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 30616 R-CEL-110141 https://reactome.org/PathwayBrowser/#/R-CEL-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Caenorhabditis elegans 30616 R-CEL-110144 https://reactome.org/PathwayBrowser/#/R-CEL-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Caenorhabditis elegans 30616 R-CEL-110145 https://reactome.org/PathwayBrowser/#/R-CEL-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Caenorhabditis elegans 30616 R-CEL-111742 https://reactome.org/PathwayBrowser/#/R-CEL-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 30616 R-CEL-111751 https://reactome.org/PathwayBrowser/#/R-CEL-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 30616 R-CEL-111804 https://reactome.org/PathwayBrowser/#/R-CEL-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 30616 R-CEL-111930 https://reactome.org/PathwayBrowser/#/R-CEL-111930 Adenylate cyclase produces cAMP IEA Caenorhabditis elegans 30616 R-CEL-111970 https://reactome.org/PathwayBrowser/#/R-CEL-111970 PKC phosphorylates GRK2 IEA Caenorhabditis elegans 30616 R-CEL-112342 https://reactome.org/PathwayBrowser/#/R-CEL-112342 Inactivation of MAP2K1 by CDK1 IEA Caenorhabditis elegans 30616 R-CEL-114683 https://reactome.org/PathwayBrowser/#/R-CEL-114683 Phosphorylation of Platelet Sec-1 IEA Caenorhabditis elegans 30616 R-CEL-114684 https://reactome.org/PathwayBrowser/#/R-CEL-114684 Phosphorylation of Syntaxin-4 IEA Caenorhabditis elegans 30616 R-CEL-1169397 https://reactome.org/PathwayBrowser/#/R-CEL-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Caenorhabditis elegans 30616 R-CEL-1169398 https://reactome.org/PathwayBrowser/#/R-CEL-1169398 ISGylation of host protein filamin B IEA Caenorhabditis elegans 30616 R-CEL-1169402 https://reactome.org/PathwayBrowser/#/R-CEL-1169402 ISGylation of E2 conjugating enzymes IEA Caenorhabditis elegans 30616 R-CEL-1169405 https://reactome.org/PathwayBrowser/#/R-CEL-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Caenorhabditis elegans 30616 R-CEL-1169406 https://reactome.org/PathwayBrowser/#/R-CEL-1169406 ISGylation of host proteins IEA Caenorhabditis elegans 30616 R-CEL-1247935 https://reactome.org/PathwayBrowser/#/R-CEL-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Caenorhabditis elegans 30616 R-CEL-1247960 https://reactome.org/PathwayBrowser/#/R-CEL-1247960 Activation of p38 MAPK IEA Caenorhabditis elegans 30616 R-CEL-1250195 https://reactome.org/PathwayBrowser/#/R-CEL-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Caenorhabditis elegans 30616 R-CEL-1250370 https://reactome.org/PathwayBrowser/#/R-CEL-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Caenorhabditis elegans 30616 R-CEL-1250462 https://reactome.org/PathwayBrowser/#/R-CEL-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Caenorhabditis elegans 30616 R-CEL-1306957 https://reactome.org/PathwayBrowser/#/R-CEL-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Caenorhabditis elegans 30616 R-CEL-1306979 https://reactome.org/PathwayBrowser/#/R-CEL-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Caenorhabditis elegans 30616 R-CEL-1307963 https://reactome.org/PathwayBrowser/#/R-CEL-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Caenorhabditis elegans 30616 R-CEL-1362270 https://reactome.org/PathwayBrowser/#/R-CEL-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Caenorhabditis elegans 30616 R-CEL-1369065 https://reactome.org/PathwayBrowser/#/R-CEL-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Caenorhabditis elegans 30616 R-CEL-1433508 https://reactome.org/PathwayBrowser/#/R-CEL-1433508 PKC alpha interacts with and phosphorylates KIT IEA Caenorhabditis elegans 30616 R-CEL-1433514 https://reactome.org/PathwayBrowser/#/R-CEL-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Caenorhabditis elegans 30616 R-CEL-1454916 https://reactome.org/PathwayBrowser/#/R-CEL-1454916 The ABCC family mediates organic anion transport IEA Caenorhabditis elegans 30616 R-CEL-1467466 https://reactome.org/PathwayBrowser/#/R-CEL-1467466 ABCA4 mediates atRAL transport IEA Caenorhabditis elegans 30616 R-CEL-1483004 https://reactome.org/PathwayBrowser/#/R-CEL-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Caenorhabditis elegans 30616 R-CEL-1483222 https://reactome.org/PathwayBrowser/#/R-CEL-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Caenorhabditis elegans 30616 R-CEL-1524186 https://reactome.org/PathwayBrowser/#/R-CEL-1524186 Phosphorylation of PLCgamma by PDGFR IEA Caenorhabditis elegans 30616 R-CEL-156673 https://reactome.org/PathwayBrowser/#/R-CEL-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Caenorhabditis elegans 30616 R-CEL-156678 https://reactome.org/PathwayBrowser/#/R-CEL-156678 Activation of Cdc25C IEA Caenorhabditis elegans 30616 R-CEL-156682 https://reactome.org/PathwayBrowser/#/R-CEL-156682 PLK1 phosphorylates NUDC IEA Caenorhabditis elegans 30616 R-CEL-159101 https://reactome.org/PathwayBrowser/#/R-CEL-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Caenorhabditis elegans 30616 R-CEL-159425 https://reactome.org/PathwayBrowser/#/R-CEL-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 30616 R-CEL-162657 https://reactome.org/PathwayBrowser/#/R-CEL-162657 Inactivation of Myt1 kinase IEA Caenorhabditis elegans 30616 R-CEL-163215 https://reactome.org/PathwayBrowser/#/R-CEL-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Caenorhabditis elegans 30616 R-CEL-1632857 https://reactome.org/PathwayBrowser/#/R-CEL-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Caenorhabditis elegans 30616 R-CEL-1638845 https://reactome.org/PathwayBrowser/#/R-CEL-1638845 CERK phosphorylates CERA to form C1P IEA Caenorhabditis elegans 30616 R-CEL-164832 https://reactome.org/PathwayBrowser/#/R-CEL-164832 ATPase synthesizes ATP IEA Caenorhabditis elegans 30616 R-CEL-164834 https://reactome.org/PathwayBrowser/#/R-CEL-164834 Enzyme-bound ATP is released IEA Caenorhabditis elegans 30616 R-CEL-165718 https://reactome.org/PathwayBrowser/#/R-CEL-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Caenorhabditis elegans 30616 R-CEL-165726 https://reactome.org/PathwayBrowser/#/R-CEL-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Caenorhabditis elegans 30616 R-CEL-165758 https://reactome.org/PathwayBrowser/#/R-CEL-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Caenorhabditis elegans 30616 R-CEL-165766 https://reactome.org/PathwayBrowser/#/R-CEL-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Caenorhabditis elegans 30616 R-CEL-1675773 https://reactome.org/PathwayBrowser/#/R-CEL-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Caenorhabditis elegans 30616 R-CEL-1675776 https://reactome.org/PathwayBrowser/#/R-CEL-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Caenorhabditis elegans 30616 R-CEL-1675780 https://reactome.org/PathwayBrowser/#/R-CEL-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Caenorhabditis elegans 30616 R-CEL-1675810 https://reactome.org/PathwayBrowser/#/R-CEL-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Caenorhabditis elegans 30616 R-CEL-1675813 https://reactome.org/PathwayBrowser/#/R-CEL-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Caenorhabditis elegans 30616 R-CEL-1675883 https://reactome.org/PathwayBrowser/#/R-CEL-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Caenorhabditis elegans 30616 R-CEL-1675939 https://reactome.org/PathwayBrowser/#/R-CEL-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Caenorhabditis elegans 30616 R-CEL-1675961 https://reactome.org/PathwayBrowser/#/R-CEL-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Caenorhabditis elegans 30616 R-CEL-1675974 https://reactome.org/PathwayBrowser/#/R-CEL-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Caenorhabditis elegans 30616 R-CEL-1676024 https://reactome.org/PathwayBrowser/#/R-CEL-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Caenorhabditis elegans 30616 R-CEL-1676048 https://reactome.org/PathwayBrowser/#/R-CEL-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Caenorhabditis elegans 30616 R-CEL-1676082 https://reactome.org/PathwayBrowser/#/R-CEL-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Caenorhabditis elegans 30616 R-CEL-1676109 https://reactome.org/PathwayBrowser/#/R-CEL-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Caenorhabditis elegans 30616 R-CEL-1676134 https://reactome.org/PathwayBrowser/#/R-CEL-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Caenorhabditis elegans 30616 R-CEL-1676145 https://reactome.org/PathwayBrowser/#/R-CEL-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Caenorhabditis elegans 30616 R-CEL-1676185 https://reactome.org/PathwayBrowser/#/R-CEL-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Caenorhabditis elegans 30616 R-CEL-168053 https://reactome.org/PathwayBrowser/#/R-CEL-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Caenorhabditis elegans 30616 R-CEL-168136 https://reactome.org/PathwayBrowser/#/R-CEL-168136 Activated JNKs phosphorylate c-JUN IEA Caenorhabditis elegans 30616 R-CEL-168162 https://reactome.org/PathwayBrowser/#/R-CEL-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Caenorhabditis elegans 30616 R-CEL-170026 https://reactome.org/PathwayBrowser/#/R-CEL-170026 Protons are translocated from the intermembrane space to the matrix IEA Caenorhabditis elegans 30616 R-CEL-170055 https://reactome.org/PathwayBrowser/#/R-CEL-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Caenorhabditis elegans 30616 R-CEL-170126 https://reactome.org/PathwayBrowser/#/R-CEL-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Caenorhabditis elegans 30616 R-CEL-170676 https://reactome.org/PathwayBrowser/#/R-CEL-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Caenorhabditis elegans 30616 R-CEL-170843 https://reactome.org/PathwayBrowser/#/R-CEL-170843 TGFBR2 phosphorylates TGFBR1 IEA Caenorhabditis elegans 30616 R-CEL-170868 https://reactome.org/PathwayBrowser/#/R-CEL-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Caenorhabditis elegans 30616 R-CEL-174367 https://reactome.org/PathwayBrowser/#/R-CEL-174367 GCL ligates L-Glu to L-Cys IEA Caenorhabditis elegans 30616 R-CEL-174389 https://reactome.org/PathwayBrowser/#/R-CEL-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Caenorhabditis elegans 30616 R-CEL-174392 https://reactome.org/PathwayBrowser/#/R-CEL-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Caenorhabditis elegans 30616 R-CEL-174394 https://reactome.org/PathwayBrowser/#/R-CEL-174394 GSS:Mg2+ dimer synthesizes GSH IEA Caenorhabditis elegans 30616 R-CEL-177284 https://reactome.org/PathwayBrowser/#/R-CEL-177284 PKA phosphorylates PDE4B IEA Caenorhabditis elegans 30616 R-CEL-177930 https://reactome.org/PathwayBrowser/#/R-CEL-177930 GAB1 phosphorylation by EGFR kinase IEA Caenorhabditis elegans 30616 R-CEL-177934 https://reactome.org/PathwayBrowser/#/R-CEL-177934 EGFR autophosphorylation IEA Caenorhabditis elegans 30616 R-CEL-177937 https://reactome.org/PathwayBrowser/#/R-CEL-177937 Phosphorylation of EGFR by SRC kinase IEA Caenorhabditis elegans 30616 R-CEL-177939 https://reactome.org/PathwayBrowser/#/R-CEL-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Caenorhabditis elegans 30616 R-CEL-182969 https://reactome.org/PathwayBrowser/#/R-CEL-182969 Phosphorylation of CBL (EGFR:CBL) IEA Caenorhabditis elegans 30616 R-CEL-183058 https://reactome.org/PathwayBrowser/#/R-CEL-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Caenorhabditis elegans 30616 R-CEL-1855153 https://reactome.org/PathwayBrowser/#/R-CEL-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-1855157 https://reactome.org/PathwayBrowser/#/R-CEL-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-1855158 https://reactome.org/PathwayBrowser/#/R-CEL-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-1855181 https://reactome.org/PathwayBrowser/#/R-CEL-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-1855182 https://reactome.org/PathwayBrowser/#/R-CEL-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-1855185 https://reactome.org/PathwayBrowser/#/R-CEL-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-1855193 https://reactome.org/PathwayBrowser/#/R-CEL-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-1855194 https://reactome.org/PathwayBrowser/#/R-CEL-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-1855206 https://reactome.org/PathwayBrowser/#/R-CEL-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-1855207 https://reactome.org/PathwayBrowser/#/R-CEL-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-1855216 https://reactome.org/PathwayBrowser/#/R-CEL-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-1855223 https://reactome.org/PathwayBrowser/#/R-CEL-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-1855224 https://reactome.org/PathwayBrowser/#/R-CEL-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-1855227 https://reactome.org/PathwayBrowser/#/R-CEL-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-1855228 https://reactome.org/PathwayBrowser/#/R-CEL-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-1855230 https://reactome.org/PathwayBrowser/#/R-CEL-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-1855233 https://reactome.org/PathwayBrowser/#/R-CEL-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-186786 https://reactome.org/PathwayBrowser/#/R-CEL-186786 Autophosphorylation of PDGF beta receptors IEA Caenorhabditis elegans 30616 R-CEL-186800 https://reactome.org/PathwayBrowser/#/R-CEL-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Caenorhabditis elegans 30616 R-CEL-187520 https://reactome.org/PathwayBrowser/#/R-CEL-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Caenorhabditis elegans 30616 R-CEL-187688 https://reactome.org/PathwayBrowser/#/R-CEL-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Caenorhabditis elegans 30616 R-CEL-187916 https://reactome.org/PathwayBrowser/#/R-CEL-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Caenorhabditis elegans 30616 R-CEL-190326 https://reactome.org/PathwayBrowser/#/R-CEL-190326 Autocatalytic phosphorylation of FGFR4 IEA Caenorhabditis elegans 30616 R-CEL-190385 https://reactome.org/PathwayBrowser/#/R-CEL-190385 Autocatalytic phosphorylation of FGFR3b IEA Caenorhabditis elegans 30616 R-CEL-190388 https://reactome.org/PathwayBrowser/#/R-CEL-190388 Autocatalytic phosphorylation of FGFR3c IEA Caenorhabditis elegans 30616 R-CEL-190408 https://reactome.org/PathwayBrowser/#/R-CEL-190408 Autocatalytic phosphorylation of FGFR2b IEA Caenorhabditis elegans 30616 R-CEL-190413 https://reactome.org/PathwayBrowser/#/R-CEL-190413 Autocatalytic phosphorylation of FGFR2c IEA Caenorhabditis elegans 30616 R-CEL-190427 https://reactome.org/PathwayBrowser/#/R-CEL-190427 Autocatalytic phosphorylation of FGFR1b IEA Caenorhabditis elegans 30616 R-CEL-190429 https://reactome.org/PathwayBrowser/#/R-CEL-190429 Autocatalytic phosphorylation of FGFR1c IEA Caenorhabditis elegans 30616 R-CEL-191062 https://reactome.org/PathwayBrowser/#/R-CEL-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Caenorhabditis elegans 30616 R-CEL-191380 https://reactome.org/PathwayBrowser/#/R-CEL-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Caenorhabditis elegans 30616 R-CEL-191414 https://reactome.org/PathwayBrowser/#/R-CEL-191414 MVD decarboxylates MVA5PP to IPPP IEA Caenorhabditis elegans 30616 R-CEL-191422 https://reactome.org/PathwayBrowser/#/R-CEL-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Caenorhabditis elegans 30616 R-CEL-192137 https://reactome.org/PathwayBrowser/#/R-CEL-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 30616 R-CEL-193401 https://reactome.org/PathwayBrowser/#/R-CEL-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 30616 R-CEL-193407 https://reactome.org/PathwayBrowser/#/R-CEL-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 30616 R-CEL-193424 https://reactome.org/PathwayBrowser/#/R-CEL-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 30616 R-CEL-193711 https://reactome.org/PathwayBrowser/#/R-CEL-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 30616 R-CEL-193727 https://reactome.org/PathwayBrowser/#/R-CEL-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 30616 R-CEL-193743 https://reactome.org/PathwayBrowser/#/R-CEL-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 30616 R-CEL-193766 https://reactome.org/PathwayBrowser/#/R-CEL-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 30616 R-CEL-194153 https://reactome.org/PathwayBrowser/#/R-CEL-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Caenorhabditis elegans 30616 R-CEL-195275 https://reactome.org/PathwayBrowser/#/R-CEL-195275 Phosphorylation of APC component of the destruction complex IEA Caenorhabditis elegans 30616 R-CEL-195283 https://reactome.org/PathwayBrowser/#/R-CEL-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Caenorhabditis elegans 30616 R-CEL-195287 https://reactome.org/PathwayBrowser/#/R-CEL-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Caenorhabditis elegans 30616 R-CEL-195300 https://reactome.org/PathwayBrowser/#/R-CEL-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Caenorhabditis elegans 30616 R-CEL-195318 https://reactome.org/PathwayBrowser/#/R-CEL-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Caenorhabditis elegans 30616 R-CEL-1963581 https://reactome.org/PathwayBrowser/#/R-CEL-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Caenorhabditis elegans 30616 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 30616 R-CEL-1963586 https://reactome.org/PathwayBrowser/#/R-CEL-1963586 SRC family kinases phosphorylate ERBB2 IEA Caenorhabditis elegans 30616 R-CEL-196753 https://reactome.org/PathwayBrowser/#/R-CEL-196753 2xPPCS ligates PPanK with Cys IEA Caenorhabditis elegans 30616 R-CEL-196754 https://reactome.org/PathwayBrowser/#/R-CEL-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Caenorhabditis elegans 30616 R-CEL-196761 https://reactome.org/PathwayBrowser/#/R-CEL-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Caenorhabditis elegans 30616 R-CEL-196773 https://reactome.org/PathwayBrowser/#/R-CEL-196773 COASY phosphorylates DP-CoA IEA Caenorhabditis elegans 30616 R-CEL-196929 https://reactome.org/PathwayBrowser/#/R-CEL-196929 FLAD1 phosphorylates FMN IEA Caenorhabditis elegans 30616 R-CEL-196964 https://reactome.org/PathwayBrowser/#/R-CEL-196964 RFK:Mg2+ phosphorylates RIB IEA Caenorhabditis elegans 30616 R-CEL-197235 https://reactome.org/PathwayBrowser/#/R-CEL-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 30616 R-CEL-197271 https://reactome.org/PathwayBrowser/#/R-CEL-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Caenorhabditis elegans 30616 R-CEL-197958 https://reactome.org/PathwayBrowser/#/R-CEL-197958 FPGS-2 transforms THF to THFPG IEA Caenorhabditis elegans 30616 R-CEL-198314 https://reactome.org/PathwayBrowser/#/R-CEL-198314 DAG stimulates protein kinase C-delta IEA Caenorhabditis elegans 30616 R-CEL-198613 https://reactome.org/PathwayBrowser/#/R-CEL-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Caenorhabditis elegans 30616 R-CEL-198621 https://reactome.org/PathwayBrowser/#/R-CEL-198621 AKT phosphorylates caspase-9 IEA Caenorhabditis elegans 30616 R-CEL-198640 https://reactome.org/PathwayBrowser/#/R-CEL-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Caenorhabditis elegans 30616 R-CEL-198669 https://reactome.org/PathwayBrowser/#/R-CEL-198669 p38MAPK phosphorylates MSK1 IEA Caenorhabditis elegans 30616 R-CEL-198746 https://reactome.org/PathwayBrowser/#/R-CEL-198746 ERK1/2/5 activate RSK1/2/3 IEA Caenorhabditis elegans 30616 R-CEL-198756 https://reactome.org/PathwayBrowser/#/R-CEL-198756 ERK1/2 phosphorylates MSK1 IEA Caenorhabditis elegans 30616 R-CEL-199298 https://reactome.org/PathwayBrowser/#/R-CEL-199298 AKT phosphorylates CREB1 IEA Caenorhabditis elegans 30616 R-CEL-199299 https://reactome.org/PathwayBrowser/#/R-CEL-199299 AKT phosphorylates FOXO transcription factors IEA Caenorhabditis elegans 30616 R-CEL-199839 https://reactome.org/PathwayBrowser/#/R-CEL-199839 AKT can phosphorylate RSK IEA Caenorhabditis elegans 30616 R-CEL-199863 https://reactome.org/PathwayBrowser/#/R-CEL-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Caenorhabditis elegans 30616 R-CEL-199895 https://reactome.org/PathwayBrowser/#/R-CEL-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Caenorhabditis elegans 30616 R-CEL-199910 https://reactome.org/PathwayBrowser/#/R-CEL-199910 MSK1 activates ATF1 IEA Caenorhabditis elegans 30616 R-CEL-199917 https://reactome.org/PathwayBrowser/#/R-CEL-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Caenorhabditis elegans 30616 R-CEL-199935 https://reactome.org/PathwayBrowser/#/R-CEL-199935 MSK1 activates CREB IEA Caenorhabditis elegans 30616 R-CEL-200423 https://reactome.org/PathwayBrowser/#/R-CEL-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Caenorhabditis elegans 30616 R-CEL-200474 https://reactome.org/PathwayBrowser/#/R-CEL-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 30616 R-CEL-200512 https://reactome.org/PathwayBrowser/#/R-CEL-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 30616 R-CEL-200555 https://reactome.org/PathwayBrowser/#/R-CEL-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Caenorhabditis elegans 30616 R-CEL-200681 https://reactome.org/PathwayBrowser/#/R-CEL-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Caenorhabditis elegans 30616 R-CEL-200682 https://reactome.org/PathwayBrowser/#/R-CEL-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Caenorhabditis elegans 30616 R-CEL-200711 https://reactome.org/PathwayBrowser/#/R-CEL-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Caenorhabditis elegans 30616 R-CEL-201035 https://reactome.org/PathwayBrowser/#/R-CEL-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Caenorhabditis elegans 30616 R-CEL-201443 https://reactome.org/PathwayBrowser/#/R-CEL-201443 Type II receptor phosphorylates type I receptor IEA Caenorhabditis elegans 30616 R-CEL-201476 https://reactome.org/PathwayBrowser/#/R-CEL-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Caenorhabditis elegans 30616 R-CEL-201510 https://reactome.org/PathwayBrowser/#/R-CEL-201510 PI3K synthesizes PIP3 downstream of ALK IEA Caenorhabditis elegans 30616 R-CEL-201677 https://reactome.org/PathwayBrowser/#/R-CEL-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Caenorhabditis elegans 30616 R-CEL-201717 https://reactome.org/PathwayBrowser/#/R-CEL-201717 CSNK2-mediated phosphorylation of DVL IEA Caenorhabditis elegans 30616 R-CEL-202111 https://reactome.org/PathwayBrowser/#/R-CEL-202111 AKT1 phosphorylates eNOS IEA Caenorhabditis elegans 30616 R-CEL-202222 https://reactome.org/PathwayBrowser/#/R-CEL-202222 Phosphorylation of PKC theta IEA Caenorhabditis elegans 30616 R-CEL-2028284 https://reactome.org/PathwayBrowser/#/R-CEL-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Caenorhabditis elegans 30616 R-CEL-2028555 https://reactome.org/PathwayBrowser/#/R-CEL-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Caenorhabditis elegans 30616 R-CEL-2028583 https://reactome.org/PathwayBrowser/#/R-CEL-2028583 Phosphorylation of YAP by LATS2 IEA Caenorhabditis elegans 30616 R-CEL-2028589 https://reactome.org/PathwayBrowser/#/R-CEL-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Caenorhabditis elegans 30616 R-CEL-2028591 https://reactome.org/PathwayBrowser/#/R-CEL-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Caenorhabditis elegans 30616 R-CEL-2028598 https://reactome.org/PathwayBrowser/#/R-CEL-2028598 Phosphorylation of YAP by LATS1 IEA Caenorhabditis elegans 30616 R-CEL-2028629 https://reactome.org/PathwayBrowser/#/R-CEL-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Caenorhabditis elegans 30616 R-CEL-2028635 https://reactome.org/PathwayBrowser/#/R-CEL-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Caenorhabditis elegans 30616 R-CEL-2028661 https://reactome.org/PathwayBrowser/#/R-CEL-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Caenorhabditis elegans 30616 R-CEL-2028670 https://reactome.org/PathwayBrowser/#/R-CEL-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Caenorhabditis elegans 30616 R-CEL-2028673 https://reactome.org/PathwayBrowser/#/R-CEL-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Caenorhabditis elegans 30616 R-CEL-2028675 https://reactome.org/PathwayBrowser/#/R-CEL-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Caenorhabditis elegans 30616 R-CEL-2028679 https://reactome.org/PathwayBrowser/#/R-CEL-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Caenorhabditis elegans 30616 R-CEL-2029454 https://reactome.org/PathwayBrowser/#/R-CEL-2029454 Autophosphorylation of PAK1 IEA Caenorhabditis elegans 30616 R-CEL-2029466 https://reactome.org/PathwayBrowser/#/R-CEL-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Caenorhabditis elegans 30616 R-CEL-2029469 https://reactome.org/PathwayBrowser/#/R-CEL-2029469 p-ERK phosphorylates WAVEs and ABI IEA Caenorhabditis elegans 30616 R-CEL-2029473 https://reactome.org/PathwayBrowser/#/R-CEL-2029473 Branching and elongation of mother and daughter filaments IEA Caenorhabditis elegans 30616 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 30616 R-CEL-2046087 https://reactome.org/PathwayBrowser/#/R-CEL-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Caenorhabditis elegans 30616 R-CEL-2046093 https://reactome.org/PathwayBrowser/#/R-CEL-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Caenorhabditis elegans 30616 R-CEL-205136 https://reactome.org/PathwayBrowser/#/R-CEL-205136 GTP-bound RAC contributes to JNK activation IEA Caenorhabditis elegans 30616 R-CEL-2060328 https://reactome.org/PathwayBrowser/#/R-CEL-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Caenorhabditis elegans 30616 R-CEL-211164 https://reactome.org/PathwayBrowser/#/R-CEL-211164 AKT phosphorylates FOXO1A IEA Caenorhabditis elegans 30616 R-CEL-2130194 https://reactome.org/PathwayBrowser/#/R-CEL-2130194 ABL phosphorylates WAVEs IEA Caenorhabditis elegans 30616 R-CEL-2176475 https://reactome.org/PathwayBrowser/#/R-CEL-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Caenorhabditis elegans 30616 R-CEL-2197690 https://reactome.org/PathwayBrowser/#/R-CEL-2197690 Detachment of WASP/WAVE IEA Caenorhabditis elegans 30616 R-CEL-2197698 https://reactome.org/PathwayBrowser/#/R-CEL-2197698 Src phosphorylate WASP,N-WASP IEA Caenorhabditis elegans 30616 R-CEL-2214351 https://reactome.org/PathwayBrowser/#/R-CEL-2214351 PLK1 phosphorylates GORASP1 IEA Caenorhabditis elegans 30616 R-CEL-2294580 https://reactome.org/PathwayBrowser/#/R-CEL-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Caenorhabditis elegans 30616 R-CEL-2294600 https://reactome.org/PathwayBrowser/#/R-CEL-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Caenorhabditis elegans 30616 R-CEL-2316434 https://reactome.org/PathwayBrowser/#/R-CEL-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 30616 R-CEL-2422927 https://reactome.org/PathwayBrowser/#/R-CEL-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Caenorhabditis elegans 30616 R-CEL-2466068 https://reactome.org/PathwayBrowser/#/R-CEL-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Caenorhabditis elegans 30616 R-CEL-2468293 https://reactome.org/PathwayBrowser/#/R-CEL-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Caenorhabditis elegans 30616 R-CEL-2581474 https://reactome.org/PathwayBrowser/#/R-CEL-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Caenorhabditis elegans 30616 R-CEL-265783 https://reactome.org/PathwayBrowser/#/R-CEL-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Caenorhabditis elegans 30616 R-CEL-2682349 https://reactome.org/PathwayBrowser/#/R-CEL-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Caenorhabditis elegans 30616 R-CEL-2730835 https://reactome.org/PathwayBrowser/#/R-CEL-2730835 Autophosphorylation of PKC-theta IEA Caenorhabditis elegans 30616 R-CEL-2730862 https://reactome.org/PathwayBrowser/#/R-CEL-2730862 Autophosphorylation of LYN kinase IEA Caenorhabditis elegans 30616 R-CEL-2984220 https://reactome.org/PathwayBrowser/#/R-CEL-2984220 CDK1:CCNB phosphorylates NEK9 IEA Caenorhabditis elegans 30616 R-CEL-2984226 https://reactome.org/PathwayBrowser/#/R-CEL-2984226 PLK1 phosphorylates NEK9 IEA Caenorhabditis elegans 30616 R-CEL-2984258 https://reactome.org/PathwayBrowser/#/R-CEL-2984258 NEK9 phosphorylates NEK6/NEK7 IEA Caenorhabditis elegans 30616 R-CEL-2990833 https://reactome.org/PathwayBrowser/#/R-CEL-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Caenorhabditis elegans 30616 R-CEL-2993447 https://reactome.org/PathwayBrowser/#/R-CEL-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Caenorhabditis elegans 30616 R-CEL-2993799 https://reactome.org/PathwayBrowser/#/R-CEL-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Caenorhabditis elegans 30616 R-CEL-2993802 https://reactome.org/PathwayBrowser/#/R-CEL-2993802 HLCS biotinylates PC:Mn2+ IEA Caenorhabditis elegans 30616 R-CEL-2993814 https://reactome.org/PathwayBrowser/#/R-CEL-2993814 HLCS biotinylates ACACA:Mn2+ IEA Caenorhabditis elegans 30616 R-CEL-3000327 https://reactome.org/PathwayBrowser/#/R-CEL-3000327 PLK1 phosphorylates BORA IEA Caenorhabditis elegans 30616 R-CEL-3095901 https://reactome.org/PathwayBrowser/#/R-CEL-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Caenorhabditis elegans 30616 R-CEL-3159253 https://reactome.org/PathwayBrowser/#/R-CEL-3159253 MMAB adenosylates cob(I)alamin IEA Caenorhabditis elegans 30616 R-CEL-3228469 https://reactome.org/PathwayBrowser/#/R-CEL-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Caenorhabditis elegans 30616 R-CEL-3249379 https://reactome.org/PathwayBrowser/#/R-CEL-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Caenorhabditis elegans 30616 R-CEL-3371422 https://reactome.org/PathwayBrowser/#/R-CEL-3371422 ATP hydrolysis by HSP70 IEA Caenorhabditis elegans 30616 R-CEL-3371435 https://reactome.org/PathwayBrowser/#/R-CEL-3371435 Constitutive phosphorylation by GSK3 IEA Caenorhabditis elegans 30616 R-CEL-3371531 https://reactome.org/PathwayBrowser/#/R-CEL-3371531 Constitutive phosphorylation by pERK1/2 IEA Caenorhabditis elegans 30616 R-CEL-3371590 https://reactome.org/PathwayBrowser/#/R-CEL-3371590 HSP70 binds to HSP40:nascent protein IEA Caenorhabditis elegans 30616 R-CEL-354073 https://reactome.org/PathwayBrowser/#/R-CEL-354073 Autophosphorylation of PTK2 at Y397 IEA Caenorhabditis elegans 30616 R-CEL-354124 https://reactome.org/PathwayBrowser/#/R-CEL-354124 Phosphorylation of pPTK2 by SRC IEA Caenorhabditis elegans 30616 R-CEL-373747 https://reactome.org/PathwayBrowser/#/R-CEL-373747 Phosphorylation of nephrin by FYN IEA Caenorhabditis elegans 30616 R-CEL-373750 https://reactome.org/PathwayBrowser/#/R-CEL-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Caenorhabditis elegans 30616 R-CEL-374664 https://reactome.org/PathwayBrowser/#/R-CEL-374664 Phosphorylation and activation of Ezrin IEA Caenorhabditis elegans 30616 R-CEL-374701 https://reactome.org/PathwayBrowser/#/R-CEL-374701 Phosphorylation of DCC by Fyn IEA Caenorhabditis elegans 30616 R-CEL-377186 https://reactome.org/PathwayBrowser/#/R-CEL-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Caenorhabditis elegans 30616 R-CEL-3772435 https://reactome.org/PathwayBrowser/#/R-CEL-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Caenorhabditis elegans 30616 R-CEL-3772436 https://reactome.org/PathwayBrowser/#/R-CEL-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Caenorhabditis elegans 30616 R-CEL-377640 https://reactome.org/PathwayBrowser/#/R-CEL-377640 Autophosphorylation of SRC IEA Caenorhabditis elegans 30616 R-CEL-380780 https://reactome.org/PathwayBrowser/#/R-CEL-380780 Activation of Src IEA Caenorhabditis elegans 30616 R-CEL-381091 https://reactome.org/PathwayBrowser/#/R-CEL-381091 IRE1 dimer autophosphorylates IEA Caenorhabditis elegans 30616 R-CEL-381111 https://reactome.org/PathwayBrowser/#/R-CEL-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Caenorhabditis elegans 30616 R-CEL-382560 https://reactome.org/PathwayBrowser/#/R-CEL-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Caenorhabditis elegans 30616 R-CEL-382575 https://reactome.org/PathwayBrowser/#/R-CEL-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Caenorhabditis elegans 30616 R-CEL-383190 https://reactome.org/PathwayBrowser/#/R-CEL-383190 HCO3- transport through ion channel IEA Caenorhabditis elegans 30616 R-CEL-389083 https://reactome.org/PathwayBrowser/#/R-CEL-389083 Autophosphorylation of PDGF alpha receptors IEA Caenorhabditis elegans 30616 R-CEL-389086 https://reactome.org/PathwayBrowser/#/R-CEL-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Caenorhabditis elegans 30616 R-CEL-389622 https://reactome.org/PathwayBrowser/#/R-CEL-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 30616 R-CEL-389632 https://reactome.org/PathwayBrowser/#/R-CEL-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 30616 R-CEL-392752 https://reactome.org/PathwayBrowser/#/R-CEL-392752 Phosphorylation of L1 by CK-II IEA Caenorhabditis elegans 30616 R-CEL-3928578 https://reactome.org/PathwayBrowser/#/R-CEL-3928578 EPH receptors autophosphorylate IEA Caenorhabditis elegans 30616 R-CEL-3928595 https://reactome.org/PathwayBrowser/#/R-CEL-3928595 N-WASP binds ARP2/3 and G-actin IEA Caenorhabditis elegans 30616 R-CEL-3928604 https://reactome.org/PathwayBrowser/#/R-CEL-3928604 SFKs phosphorylate VAV2,3 IEA Caenorhabditis elegans 30616 R-CEL-3928620 https://reactome.org/PathwayBrowser/#/R-CEL-3928620 PAK1 autophosphorylates IEA Caenorhabditis elegans 30616 R-CEL-3928625 https://reactome.org/PathwayBrowser/#/R-CEL-3928625 PAKs autophosphorylate IEA Caenorhabditis elegans 30616 R-CEL-3928627 https://reactome.org/PathwayBrowser/#/R-CEL-3928627 EPHB phosphorylates TIAM1 IEA Caenorhabditis elegans 30616 R-CEL-3928640 https://reactome.org/PathwayBrowser/#/R-CEL-3928640 PAKs phosphorylate MLC IEA Caenorhabditis elegans 30616 R-CEL-3928654 https://reactome.org/PathwayBrowser/#/R-CEL-3928654 Clathrin internalises EPH:EFN complexes IEA Caenorhabditis elegans 30616 R-CEL-399939 https://reactome.org/PathwayBrowser/#/R-CEL-399939 Autophosphorylation of PAK IEA Caenorhabditis elegans 30616 R-CEL-399944 https://reactome.org/PathwayBrowser/#/R-CEL-399944 Phosphorylation of CRMPs by Cdk5 IEA Caenorhabditis elegans 30616 R-CEL-399947 https://reactome.org/PathwayBrowser/#/R-CEL-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Caenorhabditis elegans 30616 R-CEL-399951 https://reactome.org/PathwayBrowser/#/R-CEL-399951 Phosphorylation of CRMPs by GSK3beta IEA Caenorhabditis elegans 30616 R-CEL-4086410 https://reactome.org/PathwayBrowser/#/R-CEL-4086410 CDK1 phosphorylates BORA IEA Caenorhabditis elegans 30616 R-CEL-4093332 https://reactome.org/PathwayBrowser/#/R-CEL-4093332 p-EPHB phosphorylates SDC2 IEA Caenorhabditis elegans 30616 R-CEL-4167511 https://reactome.org/PathwayBrowser/#/R-CEL-4167511 HLCS biotinylates ACACB IEA Caenorhabditis elegans 30616 R-CEL-419646 https://reactome.org/PathwayBrowser/#/R-CEL-419646 SEMA4D interacts with Plexin-B1:Met IEA Caenorhabditis elegans 30616 R-CEL-426240 https://reactome.org/PathwayBrowser/#/R-CEL-426240 DAG kinase produces phosphatidic acid from DAG IEA Caenorhabditis elegans 30616 R-CEL-428273 https://reactome.org/PathwayBrowser/#/R-CEL-428273 SPHK1 phosphorylates sphingoid IEA Caenorhabditis elegans 30616 R-CEL-428941 https://reactome.org/PathwayBrowser/#/R-CEL-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Caenorhabditis elegans 30616 R-CEL-429157 https://reactome.org/PathwayBrowser/#/R-CEL-429157 ABCC4 accumulation of dense granule contents IEA Caenorhabditis elegans 30616 R-CEL-429441 https://reactome.org/PathwayBrowser/#/R-CEL-429441 SYK activation by SRC IEA Caenorhabditis elegans 30616 R-CEL-429698 https://reactome.org/PathwayBrowser/#/R-CEL-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Caenorhabditis elegans 30616 R-CEL-429714 https://reactome.org/PathwayBrowser/#/R-CEL-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Caenorhabditis elegans 30616 R-CEL-430347 https://reactome.org/PathwayBrowser/#/R-CEL-430347 MigFilin associates with Filamin and F-actin IEA Caenorhabditis elegans 30616 R-CEL-432148 https://reactome.org/PathwayBrowser/#/R-CEL-432148 Fgr may phosphorylate p38 MAPK IEA Caenorhabditis elegans 30616 R-CEL-4332358 https://reactome.org/PathwayBrowser/#/R-CEL-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Caenorhabditis elegans 30616 R-CEL-4332363 https://reactome.org/PathwayBrowser/#/R-CEL-4332363 Autophosphorylation and activation of CAMK2 IEA Caenorhabditis elegans 30616 R-CEL-434382 https://reactome.org/PathwayBrowser/#/R-CEL-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Caenorhabditis elegans 30616 R-CEL-437162 https://reactome.org/PathwayBrowser/#/R-CEL-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Caenorhabditis elegans 30616 R-CEL-4411383 https://reactome.org/PathwayBrowser/#/R-CEL-4411383 NLK phosphorylates TCF/LEF IEA Caenorhabditis elegans 30616 R-CEL-4420206 https://reactome.org/PathwayBrowser/#/R-CEL-4420206 Phosphorylation of SRC-1 IEA Caenorhabditis elegans 30616 R-CEL-442724 https://reactome.org/PathwayBrowser/#/R-CEL-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Caenorhabditis elegans 30616 R-CEL-442749 https://reactome.org/PathwayBrowser/#/R-CEL-442749 CaMKK autophosphorylates in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-443779 https://reactome.org/PathwayBrowser/#/R-CEL-443779 Linkage of L1 with treadmilling F-actin IEA Caenorhabditis elegans 30616 R-CEL-445072 https://reactome.org/PathwayBrowser/#/R-CEL-445072 Interaction of PAK1 with Rac1-GTP IEA Caenorhabditis elegans 30616 R-CEL-445079 https://reactome.org/PathwayBrowser/#/R-CEL-445079 Phosphorylation of L1 by ERK IEA Caenorhabditis elegans 30616 R-CEL-445084 https://reactome.org/PathwayBrowser/#/R-CEL-445084 Phosphorylation of L1 by SRC IEA Caenorhabditis elegans 30616 R-CEL-445699 https://reactome.org/PathwayBrowser/#/R-CEL-445699 ATP Hydrolysis By Myosin IEA Caenorhabditis elegans 30616 R-CEL-445700 https://reactome.org/PathwayBrowser/#/R-CEL-445700 Myosin Binds ATP IEA Caenorhabditis elegans 30616 R-CEL-447074 https://reactome.org/PathwayBrowser/#/R-CEL-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Caenorhabditis elegans 30616 R-CEL-448955 https://reactome.org/PathwayBrowser/#/R-CEL-448955 Phosphorylation of MEF2 proteins by p38 IEA Caenorhabditis elegans 30616 R-CEL-450088 https://reactome.org/PathwayBrowser/#/R-CEL-450088 GLUT1 tetramer binds 4xATP IEA Caenorhabditis elegans 30616 R-CEL-450092 https://reactome.org/PathwayBrowser/#/R-CEL-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Caenorhabditis elegans 30616 R-CEL-450222 https://reactome.org/PathwayBrowser/#/R-CEL-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Caenorhabditis elegans 30616 R-CEL-450325 https://reactome.org/PathwayBrowser/#/R-CEL-450325 c-FOS activation by phospho ERK1/2 IEA Caenorhabditis elegans 30616 R-CEL-450333 https://reactome.org/PathwayBrowser/#/R-CEL-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Caenorhabditis elegans 30616 R-CEL-450463 https://reactome.org/PathwayBrowser/#/R-CEL-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Caenorhabditis elegans 30616 R-CEL-450474 https://reactome.org/PathwayBrowser/#/R-CEL-450474 MK2 phosphorylates BRF1 IEA Caenorhabditis elegans 30616 R-CEL-450490 https://reactome.org/PathwayBrowser/#/R-CEL-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Caenorhabditis elegans 30616 R-CEL-450499 https://reactome.org/PathwayBrowser/#/R-CEL-450499 Protein Kinase B (AKT) phosphorylates KSRP IEA Caenorhabditis elegans 30616 R-CEL-450827 https://reactome.org/PathwayBrowser/#/R-CEL-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Caenorhabditis elegans 30616 R-CEL-453342 https://reactome.org/PathwayBrowser/#/R-CEL-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Caenorhabditis elegans 30616 R-CEL-4793911 https://reactome.org/PathwayBrowser/#/R-CEL-4793911 MAPKAPK2 phosphorylates HSF1 IEA Caenorhabditis elegans 30616 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 30616 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 30616 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 30616 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 30616 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 30616 R-CEL-504054 https://reactome.org/PathwayBrowser/#/R-CEL-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Caenorhabditis elegans 30616 R-CEL-508040 https://reactome.org/PathwayBrowser/#/R-CEL-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Caenorhabditis elegans 30616 R-CEL-5082387 https://reactome.org/PathwayBrowser/#/R-CEL-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Caenorhabditis elegans 30616 R-CEL-5082405 https://reactome.org/PathwayBrowser/#/R-CEL-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Caenorhabditis elegans 30616 R-CEL-508308 https://reactome.org/PathwayBrowser/#/R-CEL-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Caenorhabditis elegans 30616 R-CEL-5138432 https://reactome.org/PathwayBrowser/#/R-CEL-5138432 DVL2 is phosphorylated by PKC IEA Caenorhabditis elegans 30616 R-CEL-5195402 https://reactome.org/PathwayBrowser/#/R-CEL-5195402 CDK1 phosphorylates LPIN IEA Caenorhabditis elegans 30616 R-CEL-5218804 https://reactome.org/PathwayBrowser/#/R-CEL-5218804 p38 MAPK activation by VEGFR IEA Caenorhabditis elegans 30616 R-CEL-5218805 https://reactome.org/PathwayBrowser/#/R-CEL-5218805 PKC autophosphorylates IEA Caenorhabditis elegans 30616 R-CEL-5218806 https://reactome.org/PathwayBrowser/#/R-CEL-5218806 FYN autophosphorylates IEA Caenorhabditis elegans 30616 R-CEL-5218812 https://reactome.org/PathwayBrowser/#/R-CEL-5218812 FYN phosphorylates PAK2 IEA Caenorhabditis elegans 30616 R-CEL-5218814 https://reactome.org/PathwayBrowser/#/R-CEL-5218814 PAK2 autophorylates IEA Caenorhabditis elegans 30616 R-CEL-5218819 https://reactome.org/PathwayBrowser/#/R-CEL-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 30616 R-CEL-5218821 https://reactome.org/PathwayBrowser/#/R-CEL-5218821 PDK1 phosphorylates PKC IEA Caenorhabditis elegans 30616 R-CEL-5218823 https://reactome.org/PathwayBrowser/#/R-CEL-5218823 PKC phosphorylates sphingosine kinase 1 IEA Caenorhabditis elegans 30616 R-CEL-5218854 https://reactome.org/PathwayBrowser/#/R-CEL-5218854 p-Y420-FYN is phosphorylated on S21 IEA Caenorhabditis elegans 30616 R-CEL-5218916 https://reactome.org/PathwayBrowser/#/R-CEL-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Caenorhabditis elegans 30616 R-CEL-5223317 https://reactome.org/PathwayBrowser/#/R-CEL-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 30616 R-CEL-5229343 https://reactome.org/PathwayBrowser/#/R-CEL-5229343 AXIN is phosphorylated in the destruction complex IEA Caenorhabditis elegans 30616 R-CEL-5244669 https://reactome.org/PathwayBrowser/#/R-CEL-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Caenorhabditis elegans 30616 R-CEL-5251942 https://reactome.org/PathwayBrowser/#/R-CEL-5251942 Hikeshi binds HSP70s:ATP IEA Caenorhabditis elegans 30616 R-CEL-5251955 https://reactome.org/PathwayBrowser/#/R-CEL-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Caenorhabditis elegans 30616 R-CEL-5251959 https://reactome.org/PathwayBrowser/#/R-CEL-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-5251989 https://reactome.org/PathwayBrowser/#/R-CEL-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Caenorhabditis elegans 30616 R-CEL-5252079 https://reactome.org/PathwayBrowser/#/R-CEL-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Caenorhabditis elegans 30616 R-CEL-5339524 https://reactome.org/PathwayBrowser/#/R-CEL-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Caenorhabditis elegans 30616 R-CEL-5357429 https://reactome.org/PathwayBrowser/#/R-CEL-5357429 AXL autophosphorylates on Y779 and Y821 IEA Caenorhabditis elegans 30616 R-CEL-5357472 https://reactome.org/PathwayBrowser/#/R-CEL-5357472 PAK1-3 autophosphorylates IEA Caenorhabditis elegans 30616 R-CEL-5357477 https://reactome.org/PathwayBrowser/#/R-CEL-5357477 PAK1-3 phosphorylates VE-cadherin IEA Caenorhabditis elegans 30616 R-CEL-5358475 https://reactome.org/PathwayBrowser/#/R-CEL-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Caenorhabditis elegans 30616 R-CEL-5358510 https://reactome.org/PathwayBrowser/#/R-CEL-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Caenorhabditis elegans 30616 R-CEL-5358518 https://reactome.org/PathwayBrowser/#/R-CEL-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Caenorhabditis elegans 30616 R-CEL-5358592 https://reactome.org/PathwayBrowser/#/R-CEL-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Caenorhabditis elegans 30616 R-CEL-5358597 https://reactome.org/PathwayBrowser/#/R-CEL-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Caenorhabditis elegans 30616 R-CEL-5358912 https://reactome.org/PathwayBrowser/#/R-CEL-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Caenorhabditis elegans 30616 R-CEL-548843 https://reactome.org/PathwayBrowser/#/R-CEL-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Caenorhabditis elegans 30616 R-CEL-5610727 https://reactome.org/PathwayBrowser/#/R-CEL-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Caenorhabditis elegans 30616 R-CEL-5617179 https://reactome.org/PathwayBrowser/#/R-CEL-5617179 PRKACA phosphorylates TNNI3 IEA Caenorhabditis elegans 30616 R-CEL-5618107 https://reactome.org/PathwayBrowser/#/R-CEL-5618107 ATP binding to HSP90 triggers conformation change IEA Caenorhabditis elegans 30616 R-CEL-5623667 https://reactome.org/PathwayBrowser/#/R-CEL-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Caenorhabditis elegans 30616 R-CEL-5624486 https://reactome.org/PathwayBrowser/#/R-CEL-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Caenorhabditis elegans 30616 R-CEL-5624492 https://reactome.org/PathwayBrowser/#/R-CEL-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Caenorhabditis elegans 30616 R-CEL-5626507 https://reactome.org/PathwayBrowser/#/R-CEL-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Caenorhabditis elegans 30616 R-CEL-5627775 https://reactome.org/PathwayBrowser/#/R-CEL-5627775 Autophosphorylation of PAK1,2,3 IEA Caenorhabditis elegans 30616 R-CEL-5654149 https://reactome.org/PathwayBrowser/#/R-CEL-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Caenorhabditis elegans 30616 R-CEL-5654151 https://reactome.org/PathwayBrowser/#/R-CEL-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Caenorhabditis elegans 30616 R-CEL-5654418 https://reactome.org/PathwayBrowser/#/R-CEL-5654418 Activated FGFR4 phosphorylates FRS2 IEA Caenorhabditis elegans 30616 R-CEL-5654428 https://reactome.org/PathwayBrowser/#/R-CEL-5654428 Activated FGFR4 phosphorylates SHC1 IEA Caenorhabditis elegans 30616 R-CEL-5654560 https://reactome.org/PathwayBrowser/#/R-CEL-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Caenorhabditis elegans 30616 R-CEL-5654566 https://reactome.org/PathwayBrowser/#/R-CEL-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Caenorhabditis elegans 30616 R-CEL-5654575 https://reactome.org/PathwayBrowser/#/R-CEL-5654575 Activated FGFR1 phosphorylates FRS2 IEA Caenorhabditis elegans 30616 R-CEL-5654578 https://reactome.org/PathwayBrowser/#/R-CEL-5654578 Activated FGFR1 phosphorylates FRS3 IEA Caenorhabditis elegans 30616 R-CEL-5654582 https://reactome.org/PathwayBrowser/#/R-CEL-5654582 Activated FGFR1 phosphorylates SHC1 IEA Caenorhabditis elegans 30616 R-CEL-5654653 https://reactome.org/PathwayBrowser/#/R-CEL-5654653 Activated FGFR4 phosphorylates FRS3 IEA Caenorhabditis elegans 30616 R-CEL-5654690 https://reactome.org/PathwayBrowser/#/R-CEL-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 30616 R-CEL-5654717 https://reactome.org/PathwayBrowser/#/R-CEL-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 30616 R-CEL-5654989 https://reactome.org/PathwayBrowser/#/R-CEL-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Caenorhabditis elegans 30616 R-CEL-5662466 https://reactome.org/PathwayBrowser/#/R-CEL-5662466 XYLB phosphorylates D-xylulose IEA Caenorhabditis elegans 30616 R-CEL-5665802 https://reactome.org/PathwayBrowser/#/R-CEL-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Caenorhabditis elegans 30616 R-CEL-5665868 https://reactome.org/PathwayBrowser/#/R-CEL-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Caenorhabditis elegans 30616 R-CEL-5668932 https://reactome.org/PathwayBrowser/#/R-CEL-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Caenorhabditis elegans 30616 R-CEL-5668947 https://reactome.org/PathwayBrowser/#/R-CEL-5668947 PAK1 phosphorylates myosin phosphatase IEA Caenorhabditis elegans 30616 R-CEL-5669250 https://reactome.org/PathwayBrowser/#/R-CEL-5669250 PAK1 phosphorylates FLNA IEA Caenorhabditis elegans 30616 R-CEL-5671749 https://reactome.org/PathwayBrowser/#/R-CEL-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Caenorhabditis elegans 30616 R-CEL-5671763 https://reactome.org/PathwayBrowser/#/R-CEL-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Caenorhabditis elegans 30616 R-CEL-5672008 https://reactome.org/PathwayBrowser/#/R-CEL-5672008 Thr-180 of ULK1 is phosphorylated IEA Caenorhabditis elegans 30616 R-CEL-5672010 https://reactome.org/PathwayBrowser/#/R-CEL-5672010 Active MTORC1 phosphorylates ULK1 IEA Caenorhabditis elegans 30616 R-CEL-5672012 https://reactome.org/PathwayBrowser/#/R-CEL-5672012 Beclin-1 complex phosphorylates PtdIns IEA Caenorhabditis elegans 30616 R-CEL-5672828 https://reactome.org/PathwayBrowser/#/R-CEL-5672828 mTORC1 phosphorylates AKT1S1 IEA Caenorhabditis elegans 30616 R-CEL-5672948 https://reactome.org/PathwayBrowser/#/R-CEL-5672948 MARK3 phosphorylates KSR1 IEA Caenorhabditis elegans 30616 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 30616 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 30616 R-CEL-5673768 https://reactome.org/PathwayBrowser/#/R-CEL-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Caenorhabditis elegans 30616 R-CEL-5674130 https://reactome.org/PathwayBrowser/#/R-CEL-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Caenorhabditis elegans 30616 R-CEL-5674373 https://reactome.org/PathwayBrowser/#/R-CEL-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Caenorhabditis elegans 30616 R-CEL-5674496 https://reactome.org/PathwayBrowser/#/R-CEL-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Caenorhabditis elegans 30616 R-CEL-5675194 https://reactome.org/PathwayBrowser/#/R-CEL-5675194 Activated MAPK phosphorylates RAF1 IEA Caenorhabditis elegans 30616 R-CEL-5675198 https://reactome.org/PathwayBrowser/#/R-CEL-5675198 Activated MAPKs phosphorylate BRAF IEA Caenorhabditis elegans 30616 R-CEL-5675868 https://reactome.org/PathwayBrowser/#/R-CEL-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Caenorhabditis elegans 30616 R-CEL-5678863 https://reactome.org/PathwayBrowser/#/R-CEL-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Caenorhabditis elegans 30616 R-CEL-5679041 https://reactome.org/PathwayBrowser/#/R-CEL-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 30616 R-CEL-5679205 https://reactome.org/PathwayBrowser/#/R-CEL-5679205 ULK1 phosphorylates Beclin-1 IEA Caenorhabditis elegans 30616 R-CEL-5682101 https://reactome.org/PathwayBrowser/#/R-CEL-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Caenorhabditis elegans 30616 R-CEL-5682285 https://reactome.org/PathwayBrowser/#/R-CEL-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Caenorhabditis elegans 30616 R-CEL-5683714 https://reactome.org/PathwayBrowser/#/R-CEL-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Caenorhabditis elegans 30616 R-CEL-5683792 https://reactome.org/PathwayBrowser/#/R-CEL-5683792 p-T68-CHEK2 autophosphorylates IEA Caenorhabditis elegans 30616 R-CEL-5685156 https://reactome.org/PathwayBrowser/#/R-CEL-5685156 ATR phosphorylates RPA2 IEA Caenorhabditis elegans 30616 R-CEL-5685230 https://reactome.org/PathwayBrowser/#/R-CEL-5685230 CHEK1 phosphorylates RAD51 IEA Caenorhabditis elegans 30616 R-CEL-5687086 https://reactome.org/PathwayBrowser/#/R-CEL-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Caenorhabditis elegans 30616 R-CEL-5690996 https://reactome.org/PathwayBrowser/#/R-CEL-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Caenorhabditis elegans 30616 R-CEL-5692462 https://reactome.org/PathwayBrowser/#/R-CEL-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Caenorhabditis elegans 30616 R-CEL-5692755 https://reactome.org/PathwayBrowser/#/R-CEL-5692755 CDK1 phosphorylates MAPK6 IEA Caenorhabditis elegans 30616 R-CEL-5694425 https://reactome.org/PathwayBrowser/#/R-CEL-5694425 NSF ATPase activity dissociates cis-SNARE IEA Caenorhabditis elegans 30616 R-CEL-5694494 https://reactome.org/PathwayBrowser/#/R-CEL-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Caenorhabditis elegans 30616 R-CEL-5696004 https://reactome.org/PathwayBrowser/#/R-CEL-5696004 ACSF2 ligates CoA-SH to MCFA IEA Caenorhabditis elegans 30616 R-CEL-5696074 https://reactome.org/PathwayBrowser/#/R-CEL-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Caenorhabditis elegans 30616 R-CEL-5696839 https://reactome.org/PathwayBrowser/#/R-CEL-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Caenorhabditis elegans 30616 R-CEL-6782131 https://reactome.org/PathwayBrowser/#/R-CEL-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Caenorhabditis elegans 30616 R-CEL-6787540 https://reactome.org/PathwayBrowser/#/R-CEL-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Caenorhabditis elegans 30616 R-CEL-6788810 https://reactome.org/PathwayBrowser/#/R-CEL-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 30616 R-CEL-6788855 https://reactome.org/PathwayBrowser/#/R-CEL-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Caenorhabditis elegans 30616 R-CEL-6788867 https://reactome.org/PathwayBrowser/#/R-CEL-6788867 FN3K phosphorylates ketosamines IEA Caenorhabditis elegans 30616 R-CEL-6795290 https://reactome.org/PathwayBrowser/#/R-CEL-6795290 TORC2 complex phosphorylates SGK1 IEA Caenorhabditis elegans 30616 R-CEL-6795473 https://reactome.org/PathwayBrowser/#/R-CEL-6795473 PDPK1 phosphorylates SGK1 IEA Caenorhabditis elegans 30616 R-CEL-6797606 https://reactome.org/PathwayBrowser/#/R-CEL-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Caenorhabditis elegans 30616 R-CEL-6798174 https://reactome.org/PathwayBrowser/#/R-CEL-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Caenorhabditis elegans 30616 R-CEL-6799495 https://reactome.org/PathwayBrowser/#/R-CEL-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Caenorhabditis elegans 30616 R-CEL-6801342 https://reactome.org/PathwayBrowser/#/R-CEL-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Caenorhabditis elegans 30616 R-CEL-6801456 https://reactome.org/PathwayBrowser/#/R-CEL-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Caenorhabditis elegans 30616 R-CEL-6803771 https://reactome.org/PathwayBrowser/#/R-CEL-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Caenorhabditis elegans 30616 R-CEL-6804266 https://reactome.org/PathwayBrowser/#/R-CEL-6804266 CHEK2 phosphorylates TTC5 IEA Caenorhabditis elegans 30616 R-CEL-6805640 https://reactome.org/PathwayBrowser/#/R-CEL-6805640 AKT phosphorylates KAT6A IEA Caenorhabditis elegans 30616 R-CEL-6806877 https://reactome.org/PathwayBrowser/#/R-CEL-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Caenorhabditis elegans 30616 R-CEL-6806967 https://reactome.org/PathwayBrowser/#/R-CEL-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Caenorhabditis elegans 30616 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 30616 R-CEL-6807868 https://reactome.org/PathwayBrowser/#/R-CEL-6807868 GBF1 stimulates ARF nucleotide exchange IEA Caenorhabditis elegans 30616 R-CEL-6810233 https://reactome.org/PathwayBrowser/#/R-CEL-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Caenorhabditis elegans 30616 R-CEL-6811422 https://reactome.org/PathwayBrowser/#/R-CEL-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Caenorhabditis elegans 30616 R-CEL-6811522 https://reactome.org/PathwayBrowser/#/R-CEL-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-6814120 https://reactome.org/PathwayBrowser/#/R-CEL-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Caenorhabditis elegans 30616 R-CEL-6814124 https://reactome.org/PathwayBrowser/#/R-CEL-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Caenorhabditis elegans 30616 R-CEL-6814409 https://reactome.org/PathwayBrowser/#/R-CEL-6814409 CK2 phosphorylates PDCL IEA Caenorhabditis elegans 30616 R-CEL-6814559 https://reactome.org/PathwayBrowser/#/R-CEL-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Caenorhabditis elegans 30616 R-CEL-68944 https://reactome.org/PathwayBrowser/#/R-CEL-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Caenorhabditis elegans 30616 R-CEL-69005 https://reactome.org/PathwayBrowser/#/R-CEL-69005 Cdc6 protein is phosphorylated by CDK IEA Caenorhabditis elegans 30616 R-CEL-69063 https://reactome.org/PathwayBrowser/#/R-CEL-69063 Loading of PCNA - Sliding Clamp Formation IEA Caenorhabditis elegans 30616 R-CEL-69604 https://reactome.org/PathwayBrowser/#/R-CEL-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Caenorhabditis elegans 30616 R-CEL-69608 https://reactome.org/PathwayBrowser/#/R-CEL-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Caenorhabditis elegans 30616 R-CEL-70349 https://reactome.org/PathwayBrowser/#/R-CEL-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 30616 R-CEL-70420 https://reactome.org/PathwayBrowser/#/R-CEL-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Caenorhabditis elegans 30616 R-CEL-70467 https://reactome.org/PathwayBrowser/#/R-CEL-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Caenorhabditis elegans 30616 R-CEL-70486 https://reactome.org/PathwayBrowser/#/R-CEL-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Caenorhabditis elegans 30616 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 30616 R-CEL-70599 https://reactome.org/PathwayBrowser/#/R-CEL-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Caenorhabditis elegans 30616 R-CEL-70606 https://reactome.org/PathwayBrowser/#/R-CEL-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Caenorhabditis elegans 30616 R-CEL-70773 https://reactome.org/PathwayBrowser/#/R-CEL-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Caenorhabditis elegans 30616 R-CEL-70967 https://reactome.org/PathwayBrowser/#/R-CEL-70967 IDH3 complex decarboxylates isocitrate IEA Caenorhabditis elegans 30616 R-CEL-70997 https://reactome.org/PathwayBrowser/#/R-CEL-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Caenorhabditis elegans 30616 R-CEL-71031 https://reactome.org/PathwayBrowser/#/R-CEL-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Caenorhabditis elegans 30616 R-CEL-71401 https://reactome.org/PathwayBrowser/#/R-CEL-71401 OGDH dimer decarboxylates 2-OG IEA Caenorhabditis elegans 30616 R-CEL-71541 https://reactome.org/PathwayBrowser/#/R-CEL-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Caenorhabditis elegans 30616 R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 30616 R-CEL-71735 https://reactome.org/PathwayBrowser/#/R-CEL-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Caenorhabditis elegans 30616 R-CEL-71802 https://reactome.org/PathwayBrowser/#/R-CEL-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Caenorhabditis elegans 30616 R-CEL-71850 https://reactome.org/PathwayBrowser/#/R-CEL-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Caenorhabditis elegans 30616 R-CEL-72180 https://reactome.org/PathwayBrowser/#/R-CEL-72180 Cleavage of mRNA at the 3'-end IEA Caenorhabditis elegans 30616 R-CEL-72185 https://reactome.org/PathwayBrowser/#/R-CEL-72185 mRNA polyadenylation IEA Caenorhabditis elegans 30616 R-CEL-72621 https://reactome.org/PathwayBrowser/#/R-CEL-72621 Ribosomal scanning IEA Caenorhabditis elegans 30616 R-CEL-73548 https://reactome.org/PathwayBrowser/#/R-CEL-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Caenorhabditis elegans 30616 R-CEL-73577 https://reactome.org/PathwayBrowser/#/R-CEL-73577 CAD hexamer transforms L-Gln to CAP IEA Caenorhabditis elegans 30616 R-CEL-73599 https://reactome.org/PathwayBrowser/#/R-CEL-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Caenorhabditis elegans 30616 R-CEL-73632 https://reactome.org/PathwayBrowser/#/R-CEL-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Caenorhabditis elegans 30616 R-CEL-73635 https://reactome.org/PathwayBrowser/#/R-CEL-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Caenorhabditis elegans 30616 R-CEL-73647 https://reactome.org/PathwayBrowser/#/R-CEL-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Caenorhabditis elegans 30616 R-CEL-73788 https://reactome.org/PathwayBrowser/#/R-CEL-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Caenorhabditis elegans 30616 R-CEL-73792 https://reactome.org/PathwayBrowser/#/R-CEL-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Caenorhabditis elegans 30616 R-CEL-73805 https://reactome.org/PathwayBrowser/#/R-CEL-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Caenorhabditis elegans 30616 R-CEL-73810 https://reactome.org/PathwayBrowser/#/R-CEL-73810 FGAM + ATP => AIR + ADP + Pi IEA Caenorhabditis elegans 30616 R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 30616 R-CEL-73814 https://reactome.org/PathwayBrowser/#/R-CEL-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Caenorhabditis elegans 30616 R-CEL-74220 https://reactome.org/PathwayBrowser/#/R-CEL-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Caenorhabditis elegans 30616 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 30616 R-CEL-75010 https://reactome.org/PathwayBrowser/#/R-CEL-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Caenorhabditis elegans 30616 R-CEL-75125 https://reactome.org/PathwayBrowser/#/R-CEL-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Caenorhabditis elegans 30616 R-CEL-75126 https://reactome.org/PathwayBrowser/#/R-CEL-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Caenorhabditis elegans 30616 R-CEL-75809 https://reactome.org/PathwayBrowser/#/R-CEL-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Caenorhabditis elegans 30616 R-CEL-75848 https://reactome.org/PathwayBrowser/#/R-CEL-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Caenorhabditis elegans 30616 R-CEL-75851 https://reactome.org/PathwayBrowser/#/R-CEL-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 30616 R-CEL-75887 https://reactome.org/PathwayBrowser/#/R-CEL-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Caenorhabditis elegans 30616 R-CEL-75949 https://reactome.org/PathwayBrowser/#/R-CEL-75949 RNA Polymerase II Promoter Opening: First Transition IEA Caenorhabditis elegans 30616 R-CEL-77071 https://reactome.org/PathwayBrowser/#/R-CEL-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Caenorhabditis elegans 30616 R-CEL-8847977 https://reactome.org/PathwayBrowser/#/R-CEL-8847977 FRK phosphorylates PTEN IEA Caenorhabditis elegans 30616 R-CEL-8848005 https://reactome.org/PathwayBrowser/#/R-CEL-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Caenorhabditis elegans 30616 R-CEL-8848758 https://reactome.org/PathwayBrowser/#/R-CEL-8848758 PTK6 phosphorylates AKT1 IEA Caenorhabditis elegans 30616 R-CEL-8848776 https://reactome.org/PathwayBrowser/#/R-CEL-8848776 PTK6 phosphorylates DOK1 IEA Caenorhabditis elegans 30616 R-CEL-8848818 https://reactome.org/PathwayBrowser/#/R-CEL-8848818 PTK6 phosphorylates CBL IEA Caenorhabditis elegans 30616 R-CEL-8848873 https://reactome.org/PathwayBrowser/#/R-CEL-8848873 PTK6 phosphorylates ARAP1 IEA Caenorhabditis elegans 30616 R-CEL-8849068 https://reactome.org/PathwayBrowser/#/R-CEL-8849068 PTK6 phosphorylates ARHGAP35 IEA Caenorhabditis elegans 30616 R-CEL-8849102 https://reactome.org/PathwayBrowser/#/R-CEL-8849102 SRMS phosphorylates PTK6 IEA Caenorhabditis elegans 30616 R-CEL-8849353 https://reactome.org/PathwayBrowser/#/R-CEL-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Caenorhabditis elegans 30616 R-CEL-8849463 https://reactome.org/PathwayBrowser/#/R-CEL-8849463 PTK6 phosphorylates SFPQ IEA Caenorhabditis elegans 30616 R-CEL-8850945 https://reactome.org/PathwayBrowser/#/R-CEL-8850945 Casein kinase II phosphorylates PTEN IEA Caenorhabditis elegans 30616 R-CEL-8851933 https://reactome.org/PathwayBrowser/#/R-CEL-8851933 MET phosphorylates GAB1 IEA Caenorhabditis elegans 30616 R-CEL-8852019 https://reactome.org/PathwayBrowser/#/R-CEL-8852019 MET bound PI3K generates PIP3 IEA Caenorhabditis elegans 30616 R-CEL-8852128 https://reactome.org/PathwayBrowser/#/R-CEL-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Caenorhabditis elegans 30616 R-CEL-8852131 https://reactome.org/PathwayBrowser/#/R-CEL-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Caenorhabditis elegans 30616 R-CEL-8852132 https://reactome.org/PathwayBrowser/#/R-CEL-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-8852134 https://reactome.org/PathwayBrowser/#/R-CEL-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-8852552 https://reactome.org/PathwayBrowser/#/R-CEL-8852552 MST1R autophosphorylates IEA Caenorhabditis elegans 30616 R-CEL-8856813 https://reactome.org/PathwayBrowser/#/R-CEL-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Caenorhabditis elegans 30616 R-CEL-8857925 https://reactome.org/PathwayBrowser/#/R-CEL-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Caenorhabditis elegans 30616 R-CEL-8866405 https://reactome.org/PathwayBrowser/#/R-CEL-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 30616 R-CEL-8866542 https://reactome.org/PathwayBrowser/#/R-CEL-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Caenorhabditis elegans 30616 R-CEL-8867041 https://reactome.org/PathwayBrowser/#/R-CEL-8867041 EGFR phosphorylates EPS15 IEA Caenorhabditis elegans 30616 R-CEL-8868066 https://reactome.org/PathwayBrowser/#/R-CEL-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Caenorhabditis elegans 30616 R-CEL-8868072 https://reactome.org/PathwayBrowser/#/R-CEL-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Caenorhabditis elegans 30616 R-CEL-8868118 https://reactome.org/PathwayBrowser/#/R-CEL-8868118 MAPK12 phosphorylates PTPN3 IEA Caenorhabditis elegans 30616 R-CEL-8868236 https://reactome.org/PathwayBrowser/#/R-CEL-8868236 BAR domain proteins recruit dynamin IEA Caenorhabditis elegans 30616 R-CEL-8868648 https://reactome.org/PathwayBrowser/#/R-CEL-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Caenorhabditis elegans 30616 R-CEL-8868651 https://reactome.org/PathwayBrowser/#/R-CEL-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Caenorhabditis elegans 30616 R-CEL-8868658 https://reactome.org/PathwayBrowser/#/R-CEL-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Caenorhabditis elegans 30616 R-CEL-8868659 https://reactome.org/PathwayBrowser/#/R-CEL-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Caenorhabditis elegans 30616 R-CEL-8868660 https://reactome.org/PathwayBrowser/#/R-CEL-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Caenorhabditis elegans 30616 R-CEL-8868661 https://reactome.org/PathwayBrowser/#/R-CEL-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Caenorhabditis elegans 30616 R-CEL-8871194 https://reactome.org/PathwayBrowser/#/R-CEL-8871194 RAB5 and GAPVD1 bind AP-2 IEA Caenorhabditis elegans 30616 R-CEL-8873929 https://reactome.org/PathwayBrowser/#/R-CEL-8873929 Casein kinase II phosphorylates STARD10 IEA Caenorhabditis elegans 30616 R-CEL-8874078 https://reactome.org/PathwayBrowser/#/R-CEL-8874078 PTK2 autophosphorylates IEA Caenorhabditis elegans 30616 R-CEL-8874080 https://reactome.org/PathwayBrowser/#/R-CEL-8874080 SRC phosphorylates PTK2 IEA Caenorhabditis elegans 30616 R-CEL-8874082 https://reactome.org/PathwayBrowser/#/R-CEL-8874082 MET phosphorylates PTK2 IEA Caenorhabditis elegans 30616 R-CEL-8875451 https://reactome.org/PathwayBrowser/#/R-CEL-8875451 MET phosphorylates CBL IEA Caenorhabditis elegans 30616 R-CEL-8875817 https://reactome.org/PathwayBrowser/#/R-CEL-8875817 MET phosphorylates STAT3 IEA Caenorhabditis elegans 30616 R-CEL-8876889 https://reactome.org/PathwayBrowser/#/R-CEL-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 30616 R-CEL-8877691 https://reactome.org/PathwayBrowser/#/R-CEL-8877691 MAP2K6 phosphorylates PIP4K2B IEA Caenorhabditis elegans 30616 R-CEL-8878050 https://reactome.org/PathwayBrowser/#/R-CEL-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Caenorhabditis elegans 30616 R-CEL-8878054 https://reactome.org/PathwayBrowser/#/R-CEL-8878054 HIPK2 phosphorylates RUNX1 IEA Caenorhabditis elegans 30616 R-CEL-8933446 https://reactome.org/PathwayBrowser/#/R-CEL-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Caenorhabditis elegans 30616 R-CEL-8937807 https://reactome.org/PathwayBrowser/#/R-CEL-8937807 SRC phosphorylates RUNX3 IEA Caenorhabditis elegans 30616 R-CEL-8939959 https://reactome.org/PathwayBrowser/#/R-CEL-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Caenorhabditis elegans 30616 R-CEL-8944454 https://reactome.org/PathwayBrowser/#/R-CEL-8944454 mTORC1 phosphorylates MAF1 IEA Caenorhabditis elegans 30616 R-CEL-8948039 https://reactome.org/PathwayBrowser/#/R-CEL-8948039 FUNDC1 is phosphorylated by CK2 IEA Caenorhabditis elegans 30616 R-CEL-8948143 https://reactome.org/PathwayBrowser/#/R-CEL-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Caenorhabditis elegans 30616 R-CEL-8948146 https://reactome.org/PathwayBrowser/#/R-CEL-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Caenorhabditis elegans 30616 R-CEL-8948757 https://reactome.org/PathwayBrowser/#/R-CEL-8948757 AKT phosphorylates MKRN1 IEA Caenorhabditis elegans 30616 R-CEL-8951648 https://reactome.org/PathwayBrowser/#/R-CEL-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Caenorhabditis elegans 30616 R-CEL-8951656 https://reactome.org/PathwayBrowser/#/R-CEL-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Caenorhabditis elegans 30616 R-CEL-8952289 https://reactome.org/PathwayBrowser/#/R-CEL-8952289 FAM20C phosphorylates FAM20C substrates IEA Caenorhabditis elegans 30616 R-CEL-8954327 https://reactome.org/PathwayBrowser/#/R-CEL-8954327 UCKL1 phosphorylates urindine, cytidine IEA Caenorhabditis elegans 30616 R-CEL-8955030 https://reactome.org/PathwayBrowser/#/R-CEL-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Caenorhabditis elegans 30616 R-CEL-8955844 https://reactome.org/PathwayBrowser/#/R-CEL-8955844 RBKS phosphorylates ribose to R5P IEA Caenorhabditis elegans 30616 R-CEL-8956659 https://reactome.org/PathwayBrowser/#/R-CEL-8956659 ABL1 phosphorylates YAP1 IEA Caenorhabditis elegans 30616 R-CEL-8959510 https://reactome.org/PathwayBrowser/#/R-CEL-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Caenorhabditis elegans 30616 R-CEL-8959719 https://reactome.org/PathwayBrowser/#/R-CEL-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Caenorhabditis elegans 30616 R-CEL-8964242 https://reactome.org/PathwayBrowser/#/R-CEL-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Caenorhabditis elegans 30616 R-CEL-9008043 https://reactome.org/PathwayBrowser/#/R-CEL-9008043 MAPK8 phosphorylation IEA Caenorhabditis elegans 30616 R-CEL-9009072 https://reactome.org/PathwayBrowser/#/R-CEL-9009072 STAT3 phosphorylation IEA Caenorhabditis elegans 30616 R-CEL-9009282 https://reactome.org/PathwayBrowser/#/R-CEL-9009282 CDK1 phosphorylates RUNX2 IEA Caenorhabditis elegans 30616 R-CEL-9009950 https://reactome.org/PathwayBrowser/#/R-CEL-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Caenorhabditis elegans 30616 R-CEL-9012268 https://reactome.org/PathwayBrowser/#/R-CEL-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 30616 R-CEL-9012319 https://reactome.org/PathwayBrowser/#/R-CEL-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Caenorhabditis elegans 30616 R-CEL-9014741 https://reactome.org/PathwayBrowser/#/R-CEL-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Caenorhabditis elegans 30616 R-CEL-9014766 https://reactome.org/PathwayBrowser/#/R-CEL-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Caenorhabditis elegans 30616 R-CEL-9021357 https://reactome.org/PathwayBrowser/#/R-CEL-9021357 PRKCI phosphorylates ELF3 IEA Caenorhabditis elegans 30616 R-CEL-913996 https://reactome.org/PathwayBrowser/#/R-CEL-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Caenorhabditis elegans 30616 R-CEL-917841 https://reactome.org/PathwayBrowser/#/R-CEL-917841 Acidification of Tf:TfR1 containing endosome IEA Caenorhabditis elegans 30616 R-CEL-917979 https://reactome.org/PathwayBrowser/#/R-CEL-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Caenorhabditis elegans 30616 R-CEL-927889 https://reactome.org/PathwayBrowser/#/R-CEL-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Caenorhabditis elegans 30616 R-CEL-936883 https://reactome.org/PathwayBrowser/#/R-CEL-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Caenorhabditis elegans 30616 R-CEL-936895 https://reactome.org/PathwayBrowser/#/R-CEL-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Caenorhabditis elegans 30616 R-CEL-939763 https://reactome.org/PathwayBrowser/#/R-CEL-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Caenorhabditis elegans 30616 R-CEL-947531 https://reactome.org/PathwayBrowser/#/R-CEL-947531 Molybdenum ion transfer onto molybdopterin IEA Caenorhabditis elegans 30616 R-CEL-947591 https://reactome.org/PathwayBrowser/#/R-CEL-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Caenorhabditis elegans 30616 R-CEL-9604328 https://reactome.org/PathwayBrowser/#/R-CEL-9604328 AKT1 phosphorylates NOTCH4 IEA Caenorhabditis elegans 30616 R-CEL-9610153 https://reactome.org/PathwayBrowser/#/R-CEL-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Caenorhabditis elegans 30616 R-CEL-9610156 https://reactome.org/PathwayBrowser/#/R-CEL-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Caenorhabditis elegans 30616 R-CEL-9610163 https://reactome.org/PathwayBrowser/#/R-CEL-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Caenorhabditis elegans 30616 R-CEL-9612501 https://reactome.org/PathwayBrowser/#/R-CEL-9612501 SGK phosphorylates CREB1 IEA Caenorhabditis elegans 30616 R-CEL-9612509 https://reactome.org/PathwayBrowser/#/R-CEL-9612509 SGK phosphorylates SRF IEA Caenorhabditis elegans 30616 R-CEL-9613494 https://reactome.org/PathwayBrowser/#/R-CEL-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Caenorhabditis elegans 30616 R-CEL-9619355 https://reactome.org/PathwayBrowser/#/R-CEL-9619355 CaMKK autophosphorylates in the cytosol IEA Caenorhabditis elegans 30616 R-CEL-9624526 https://reactome.org/PathwayBrowser/#/R-CEL-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Caenorhabditis elegans 30616 R-CEL-9625487 https://reactome.org/PathwayBrowser/#/R-CEL-9625487 PTK2 autophosphorylates downstream of EGFR IEA Caenorhabditis elegans 30616 R-CEL-9632858 https://reactome.org/PathwayBrowser/#/R-CEL-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Caenorhabditis elegans 30616 R-CEL-9648089 https://reactome.org/PathwayBrowser/#/R-CEL-9648089 NEK6 and NEK7 phosphorylate EML4 IEA Caenorhabditis elegans 30616 R-CEL-964958 https://reactome.org/PathwayBrowser/#/R-CEL-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Caenorhabditis elegans 30616 R-CEL-964962 https://reactome.org/PathwayBrowser/#/R-CEL-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Caenorhabditis elegans 30616 R-CEL-964970 https://reactome.org/PathwayBrowser/#/R-CEL-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Caenorhabditis elegans 30616 R-CEL-9653503 https://reactome.org/PathwayBrowser/#/R-CEL-9653503 KRAS4B is phosphorylated on serine 181 IEA Caenorhabditis elegans 30616 R-CEL-9661417 https://reactome.org/PathwayBrowser/#/R-CEL-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 30616 R-CEL-9684118 https://reactome.org/PathwayBrowser/#/R-CEL-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Caenorhabditis elegans 30616 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 30616 R-CEL-9699579 https://reactome.org/PathwayBrowser/#/R-CEL-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Caenorhabditis elegans 30616 R-CEL-9706390 https://reactome.org/PathwayBrowser/#/R-CEL-9706390 RHOBTB3 binds interacting proteins at trans-Golgi network IEA Caenorhabditis elegans 30616 R-CEL-9706393 https://reactome.org/PathwayBrowser/#/R-CEL-9706393 RHOBTB3 binds ATP IEA Caenorhabditis elegans 30616 R-CEL-9706399 https://reactome.org/PathwayBrowser/#/R-CEL-9706399 RHOBTB3 hydrolyzes ATP IEA Caenorhabditis elegans 30616 R-CEL-9731111 https://reactome.org/PathwayBrowser/#/R-CEL-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Caenorhabditis elegans 30616 R-CEL-9734535 https://reactome.org/PathwayBrowser/#/R-CEL-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Caenorhabditis elegans 30616 R-CEL-9734547 https://reactome.org/PathwayBrowser/#/R-CEL-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Caenorhabditis elegans 30616 R-CEL-9748949 https://reactome.org/PathwayBrowser/#/R-CEL-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Caenorhabditis elegans 30616 R-CEL-9748957 https://reactome.org/PathwayBrowser/#/R-CEL-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Caenorhabditis elegans 30616 R-CEL-9748963 https://reactome.org/PathwayBrowser/#/R-CEL-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Caenorhabditis elegans 30616 R-CEL-9748969 https://reactome.org/PathwayBrowser/#/R-CEL-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Caenorhabditis elegans 30616 R-CEL-9748999 https://reactome.org/PathwayBrowser/#/R-CEL-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Caenorhabditis elegans 30616 R-CEL-9750546 https://reactome.org/PathwayBrowser/#/R-CEL-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 30616 R-CEL-9750617 https://reactome.org/PathwayBrowser/#/R-CEL-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 30616 R-CEL-9750656 https://reactome.org/PathwayBrowser/#/R-CEL-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Caenorhabditis elegans 30616 R-CEL-9753278 https://reactome.org/PathwayBrowser/#/R-CEL-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 30616 R-CEL-9753283 https://reactome.org/PathwayBrowser/#/R-CEL-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 30616 R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 30616 R-CEL-9754974 https://reactome.org/PathwayBrowser/#/R-CEL-9754974 ADK phosphorylates RBV IEA Caenorhabditis elegans 30616 R-CEL-9755013 https://reactome.org/PathwayBrowser/#/R-CEL-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Caenorhabditis elegans 30616 R-CEL-9762094 https://reactome.org/PathwayBrowser/#/R-CEL-9762094 GSK3B phosphorylates p-NFE2L2 IEA Caenorhabditis elegans 30616 R-CEL-9770141 https://reactome.org/PathwayBrowser/#/R-CEL-9770141 Formation of the Spliceosomal C* complex IEA Caenorhabditis elegans 30616 R-CEL-9794120 https://reactome.org/PathwayBrowser/#/R-CEL-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Caenorhabditis elegans 30616 R-CEL-9794572 https://reactome.org/PathwayBrowser/#/R-CEL-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Caenorhabditis elegans 30616 R-CEL-9796053 https://reactome.org/PathwayBrowser/#/R-CEL-9796053 PRKCI phosphorylates NFE2L2 IEA Caenorhabditis elegans 30616 R-CEL-9796067 https://reactome.org/PathwayBrowser/#/R-CEL-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Caenorhabditis elegans 30616 R-CEL-9824977 https://reactome.org/PathwayBrowser/#/R-CEL-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Caenorhabditis elegans 30616 R-CEL-9824994 https://reactome.org/PathwayBrowser/#/R-CEL-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Caenorhabditis elegans 30616 R-CEL-9824995 https://reactome.org/PathwayBrowser/#/R-CEL-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Caenorhabditis elegans 30616 R-CEL-9824999 https://reactome.org/PathwayBrowser/#/R-CEL-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Caenorhabditis elegans 30616 R-CEL-983140 https://reactome.org/PathwayBrowser/#/R-CEL-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Caenorhabditis elegans 30616 R-CEL-983144 https://reactome.org/PathwayBrowser/#/R-CEL-983144 Transport of Antigen peptide in to ER IEA Caenorhabditis elegans 30616 R-CEL-983153 https://reactome.org/PathwayBrowser/#/R-CEL-983153 E1 mediated ubiquitin activation IEA Caenorhabditis elegans 30616 R-CEL-983156 https://reactome.org/PathwayBrowser/#/R-CEL-983156 Polyubiquitination of substrate IEA Caenorhabditis elegans 30616 R-CEL-983259 https://reactome.org/PathwayBrowser/#/R-CEL-983259 Kinesins move along microtubules consuming ATP IEA Caenorhabditis elegans 30616 R-CEL-9833973 https://reactome.org/PathwayBrowser/#/R-CEL-9833973 ISGylation of PKR IEA Caenorhabditis elegans 30616 R-CEL-9836159 https://reactome.org/PathwayBrowser/#/R-CEL-9836159 p-PKR dimer phosphorylates DHX9 IEA Caenorhabditis elegans 30616 R-CEL-9836184 https://reactome.org/PathwayBrowser/#/R-CEL-9836184 p-PKR dimer phosphorylates CDK1 IEA Caenorhabditis elegans 30616 R-CEL-9836322 https://reactome.org/PathwayBrowser/#/R-CEL-9836322 p-PKR dimer phosphorylates MKK6 IEA Caenorhabditis elegans 30616 R-CEL-9836383 https://reactome.org/PathwayBrowser/#/R-CEL-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Caenorhabditis elegans 30616 R-CEL-9836617 https://reactome.org/PathwayBrowser/#/R-CEL-9836617 p-PKR dimer phosphorylates SPHK1 IEA Caenorhabditis elegans 30616 R-CEL-9836664 https://reactome.org/PathwayBrowser/#/R-CEL-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Caenorhabditis elegans 30616 R-CEL-9837337 https://reactome.org/PathwayBrowser/#/R-CEL-9837337 DCAKD phosphorylates DP-CoA IEA Caenorhabditis elegans 30616 R-CEL-9838004 https://reactome.org/PathwayBrowser/#/R-CEL-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Caenorhabditis elegans 30616 R-CEL-9838081 https://reactome.org/PathwayBrowser/#/R-CEL-9838081 LONP1 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 30616 R-CEL-9838289 https://reactome.org/PathwayBrowser/#/R-CEL-9838289 CLPXP degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 30616 R-CEL-9838321 https://reactome.org/PathwayBrowser/#/R-CEL-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Caenorhabditis elegans 30616 R-CEL-9839059 https://reactome.org/PathwayBrowser/#/R-CEL-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Caenorhabditis elegans 30616 R-CEL-9839105 https://reactome.org/PathwayBrowser/#/R-CEL-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 30616 R-CEL-9839113 https://reactome.org/PathwayBrowser/#/R-CEL-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Caenorhabditis elegans 30616 R-CEL-9843721 https://reactome.org/PathwayBrowser/#/R-CEL-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Caenorhabditis elegans 30616 R-CFA-109624 https://reactome.org/PathwayBrowser/#/R-CFA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Canis familiaris 30616 R-CFA-109671 https://reactome.org/PathwayBrowser/#/R-CFA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Canis familiaris 30616 R-CFA-109699 https://reactome.org/PathwayBrowser/#/R-CFA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-109759 https://reactome.org/PathwayBrowser/#/R-CFA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Canis familiaris 30616 R-CFA-109822 https://reactome.org/PathwayBrowser/#/R-CFA-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Canis familiaris 30616 R-CFA-109823 https://reactome.org/PathwayBrowser/#/R-CFA-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Canis familiaris 30616 R-CFA-109862 https://reactome.org/PathwayBrowser/#/R-CFA-109862 MAP2K2 phosphorylates MAPK1 IEA Canis familiaris 30616 R-CFA-109903 https://reactome.org/PathwayBrowser/#/R-CFA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Canis familiaris 30616 R-CFA-110133 https://reactome.org/PathwayBrowser/#/R-CFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Canis familiaris 30616 R-CFA-110137 https://reactome.org/PathwayBrowser/#/R-CFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Canis familiaris 30616 R-CFA-110138 https://reactome.org/PathwayBrowser/#/R-CFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 30616 R-CFA-110141 https://reactome.org/PathwayBrowser/#/R-CFA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Canis familiaris 30616 R-CFA-110144 https://reactome.org/PathwayBrowser/#/R-CFA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Canis familiaris 30616 R-CFA-110145 https://reactome.org/PathwayBrowser/#/R-CFA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Canis familiaris 30616 R-CFA-1112510 https://reactome.org/PathwayBrowser/#/R-CFA-1112510 IL6ST is tyrosine phosphorylated IEA Canis familiaris 30616 R-CFA-1112514 https://reactome.org/PathwayBrowser/#/R-CFA-1112514 JAK activation IEA Canis familiaris 30616 R-CFA-1112602 https://reactome.org/PathwayBrowser/#/R-CFA-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Canis familiaris 30616 R-CFA-1112703 https://reactome.org/PathwayBrowser/#/R-CFA-1112703 PTPN11 is phosphorylated IEA Canis familiaris 30616 R-CFA-1112727 https://reactome.org/PathwayBrowser/#/R-CFA-1112727 Serine phosphorylation of STATs IEA Canis familiaris 30616 R-CFA-111742 https://reactome.org/PathwayBrowser/#/R-CFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 30616 R-CFA-111751 https://reactome.org/PathwayBrowser/#/R-CFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 30616 R-CFA-111804 https://reactome.org/PathwayBrowser/#/R-CFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 30616 R-CFA-111898 https://reactome.org/PathwayBrowser/#/R-CFA-111898 Phosphorylation of cPLA2 by ERK-2 IEA Canis familiaris 30616 R-CFA-111930 https://reactome.org/PathwayBrowser/#/R-CFA-111930 Adenylate cyclase produces cAMP IEA Canis familiaris 30616 R-CFA-111970 https://reactome.org/PathwayBrowser/#/R-CFA-111970 PKC phosphorylates GRK2 IEA Canis familiaris 30616 R-CFA-112381 https://reactome.org/PathwayBrowser/#/R-CFA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Canis familiaris 30616 R-CFA-114252 https://reactome.org/PathwayBrowser/#/R-CFA-114252 Cleavage of Procaspase-3 by the apoptosome IEA Canis familiaris 30616 R-CFA-114254 https://reactome.org/PathwayBrowser/#/R-CFA-114254 CYCS binds to APAF1 IEA Canis familiaris 30616 R-CFA-114256 https://reactome.org/PathwayBrowser/#/R-CFA-114256 CYCS:APAF1 binds procaspase-9 IEA Canis familiaris 30616 R-CFA-114261 https://reactome.org/PathwayBrowser/#/R-CFA-114261 Cleavage of Procaspase-7 by the apoptosome IEA Canis familiaris 30616 R-CFA-114600 https://reactome.org/PathwayBrowser/#/R-CFA-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Canis familiaris 30616 R-CFA-114683 https://reactome.org/PathwayBrowser/#/R-CFA-114683 Phosphorylation of Platelet Sec-1 IEA Canis familiaris 30616 R-CFA-114684 https://reactome.org/PathwayBrowser/#/R-CFA-114684 Phosphorylation of Syntaxin-4 IEA Canis familiaris 30616 R-CFA-1168459 https://reactome.org/PathwayBrowser/#/R-CFA-1168459 Lyn activates ERK IEA Canis familiaris 30616 R-CFA-1168635 https://reactome.org/PathwayBrowser/#/R-CFA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Canis familiaris 30616 R-CFA-1168638 https://reactome.org/PathwayBrowser/#/R-CFA-1168638 Activated IKK phosphorylates I-kappaB IEA Canis familiaris 30616 R-CFA-1169397 https://reactome.org/PathwayBrowser/#/R-CFA-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Canis familiaris 30616 R-CFA-1181149 https://reactome.org/PathwayBrowser/#/R-CFA-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Canis familiaris 30616 R-CFA-1226094 https://reactome.org/PathwayBrowser/#/R-CFA-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Canis familiaris 30616 R-CFA-1226095 https://reactome.org/PathwayBrowser/#/R-CFA-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Canis familiaris 30616 R-CFA-1247935 https://reactome.org/PathwayBrowser/#/R-CFA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Canis familiaris 30616 R-CFA-1247960 https://reactome.org/PathwayBrowser/#/R-CFA-1247960 Activation of p38 MAPK IEA Canis familiaris 30616 R-CFA-1250195 https://reactome.org/PathwayBrowser/#/R-CFA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Canis familiaris 30616 R-CFA-1250315 https://reactome.org/PathwayBrowser/#/R-CFA-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Canis familiaris 30616 R-CFA-1250348 https://reactome.org/PathwayBrowser/#/R-CFA-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Canis familiaris 30616 R-CFA-1250370 https://reactome.org/PathwayBrowser/#/R-CFA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Canis familiaris 30616 R-CFA-1250462 https://reactome.org/PathwayBrowser/#/R-CFA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Canis familiaris 30616 R-CFA-1295540 https://reactome.org/PathwayBrowser/#/R-CFA-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Canis familiaris 30616 R-CFA-1295609 https://reactome.org/PathwayBrowser/#/R-CFA-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Canis familiaris 30616 R-CFA-1296024 https://reactome.org/PathwayBrowser/#/R-CFA-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Canis familiaris 30616 R-CFA-1306957 https://reactome.org/PathwayBrowser/#/R-CFA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Canis familiaris 30616 R-CFA-1306979 https://reactome.org/PathwayBrowser/#/R-CFA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Canis familiaris 30616 R-CFA-1307963 https://reactome.org/PathwayBrowser/#/R-CFA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Canis familiaris 30616 R-CFA-1362270 https://reactome.org/PathwayBrowser/#/R-CFA-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Canis familiaris 30616 R-CFA-1369065 https://reactome.org/PathwayBrowser/#/R-CFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Canis familiaris 30616 R-CFA-1370505 https://reactome.org/PathwayBrowser/#/R-CFA-1370505 PRLR is phosphorylated at Ser-349 IEA Canis familiaris 30616 R-CFA-139855 https://reactome.org/PathwayBrowser/#/R-CFA-139855 P2X1-mediated entry of Ca++ from plasma IEA Canis familiaris 30616 R-CFA-139908 https://reactome.org/PathwayBrowser/#/R-CFA-139908 Phosphorylation of DLC2 by MAPK8 IEA Canis familiaris 30616 R-CFA-139918 https://reactome.org/PathwayBrowser/#/R-CFA-139918 Phosphorylation of BIM by JNK IEA Canis familiaris 30616 R-CFA-1433418 https://reactome.org/PathwayBrowser/#/R-CFA-1433418 Phosphorylation of JAK2 IEA Canis familiaris 30616 R-CFA-1433454 https://reactome.org/PathwayBrowser/#/R-CFA-1433454 Phosphorylation of GAB2 by SFKs IEA Canis familiaris 30616 R-CFA-1433488 https://reactome.org/PathwayBrowser/#/R-CFA-1433488 Phosphorylation of SHP2 by SFKs IEA Canis familiaris 30616 R-CFA-1433506 https://reactome.org/PathwayBrowser/#/R-CFA-1433506 Phosphorylation of APS IEA Canis familiaris 30616 R-CFA-1433508 https://reactome.org/PathwayBrowser/#/R-CFA-1433508 PKC alpha interacts with and phosphorylates KIT IEA Canis familiaris 30616 R-CFA-1433514 https://reactome.org/PathwayBrowser/#/R-CFA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Canis familiaris 30616 R-CFA-1433542 https://reactome.org/PathwayBrowser/#/R-CFA-1433542 Phosphorylation and activation of VAV1 IEA Canis familiaris 30616 R-CFA-1454916 https://reactome.org/PathwayBrowser/#/R-CFA-1454916 The ABCC family mediates organic anion transport IEA Canis familiaris 30616 R-CFA-1454928 https://reactome.org/PathwayBrowser/#/R-CFA-1454928 ABCG4 may mediate cholesterol efflux IEA Canis familiaris 30616 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-1467466 https://reactome.org/PathwayBrowser/#/R-CFA-1467466 ABCA4 mediates atRAL transport IEA Canis familiaris 30616 R-CFA-1470009 https://reactome.org/PathwayBrowser/#/R-CFA-1470009 Phosphorylation of STATs IEA Canis familiaris 30616 R-CFA-1472121 https://reactome.org/PathwayBrowser/#/R-CFA-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Canis familiaris 30616 R-CFA-1483004 https://reactome.org/PathwayBrowser/#/R-CFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Canis familiaris 30616 R-CFA-1483222 https://reactome.org/PathwayBrowser/#/R-CFA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Canis familiaris 30616 R-CFA-1497853 https://reactome.org/PathwayBrowser/#/R-CFA-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Canis familiaris 30616 R-CFA-1524186 https://reactome.org/PathwayBrowser/#/R-CFA-1524186 Phosphorylation of PLCgamma by PDGFR IEA Canis familiaris 30616 R-CFA-1549526 https://reactome.org/PathwayBrowser/#/R-CFA-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Canis familiaris 30616 R-CFA-156673 https://reactome.org/PathwayBrowser/#/R-CFA-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Canis familiaris 30616 R-CFA-156678 https://reactome.org/PathwayBrowser/#/R-CFA-156678 Activation of Cdc25C IEA Canis familiaris 30616 R-CFA-156682 https://reactome.org/PathwayBrowser/#/R-CFA-156682 PLK1 phosphorylates NUDC IEA Canis familiaris 30616 R-CFA-156699 https://reactome.org/PathwayBrowser/#/R-CFA-156699 Inactivation of Wee1 kinase IEA Canis familiaris 30616 R-CFA-156723 https://reactome.org/PathwayBrowser/#/R-CFA-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Canis familiaris 30616 R-CFA-159425 https://reactome.org/PathwayBrowser/#/R-CFA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 30616 R-CFA-159443 https://reactome.org/PathwayBrowser/#/R-CFA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 30616 R-CFA-159567 https://reactome.org/PathwayBrowser/#/R-CFA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Canis familiaris 30616 R-CFA-162657 https://reactome.org/PathwayBrowser/#/R-CFA-162657 Inactivation of Myt1 kinase IEA Canis familiaris 30616 R-CFA-163010 https://reactome.org/PathwayBrowser/#/R-CFA-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Canis familiaris 30616 R-CFA-163215 https://reactome.org/PathwayBrowser/#/R-CFA-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Canis familiaris 30616 R-CFA-1632857 https://reactome.org/PathwayBrowser/#/R-CFA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Canis familiaris 30616 R-CFA-1638803 https://reactome.org/PathwayBrowser/#/R-CFA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Canis familiaris 30616 R-CFA-1638845 https://reactome.org/PathwayBrowser/#/R-CFA-1638845 CERK phosphorylates CERA to form C1P IEA Canis familiaris 30616 R-CFA-164832 https://reactome.org/PathwayBrowser/#/R-CFA-164832 ATPase synthesizes ATP IEA Canis familiaris 30616 R-CFA-164834 https://reactome.org/PathwayBrowser/#/R-CFA-164834 Enzyme-bound ATP is released IEA Canis familiaris 30616 R-CFA-165692 https://reactome.org/PathwayBrowser/#/R-CFA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Canis familiaris 30616 R-CFA-165718 https://reactome.org/PathwayBrowser/#/R-CFA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Canis familiaris 30616 R-CFA-165726 https://reactome.org/PathwayBrowser/#/R-CFA-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Canis familiaris 30616 R-CFA-165758 https://reactome.org/PathwayBrowser/#/R-CFA-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Canis familiaris 30616 R-CFA-165766 https://reactome.org/PathwayBrowser/#/R-CFA-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Canis familiaris 30616 R-CFA-165777 https://reactome.org/PathwayBrowser/#/R-CFA-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Canis familiaris 30616 R-CFA-166245 https://reactome.org/PathwayBrowser/#/R-CFA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Canis familiaris 30616 R-CFA-1675773 https://reactome.org/PathwayBrowser/#/R-CFA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Canis familiaris 30616 R-CFA-1675776 https://reactome.org/PathwayBrowser/#/R-CFA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Canis familiaris 30616 R-CFA-1675780 https://reactome.org/PathwayBrowser/#/R-CFA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Canis familiaris 30616 R-CFA-1675810 https://reactome.org/PathwayBrowser/#/R-CFA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Canis familiaris 30616 R-CFA-1675813 https://reactome.org/PathwayBrowser/#/R-CFA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Canis familiaris 30616 R-CFA-1675883 https://reactome.org/PathwayBrowser/#/R-CFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Canis familiaris 30616 R-CFA-1675928 https://reactome.org/PathwayBrowser/#/R-CFA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Canis familiaris 30616 R-CFA-1675939 https://reactome.org/PathwayBrowser/#/R-CFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Canis familiaris 30616 R-CFA-1675961 https://reactome.org/PathwayBrowser/#/R-CFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Canis familiaris 30616 R-CFA-1675974 https://reactome.org/PathwayBrowser/#/R-CFA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Canis familiaris 30616 R-CFA-1676024 https://reactome.org/PathwayBrowser/#/R-CFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Canis familiaris 30616 R-CFA-1676048 https://reactome.org/PathwayBrowser/#/R-CFA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Canis familiaris 30616 R-CFA-1676082 https://reactome.org/PathwayBrowser/#/R-CFA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Canis familiaris 30616 R-CFA-1676109 https://reactome.org/PathwayBrowser/#/R-CFA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Canis familiaris 30616 R-CFA-1676134 https://reactome.org/PathwayBrowser/#/R-CFA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Canis familiaris 30616 R-CFA-1676145 https://reactome.org/PathwayBrowser/#/R-CFA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Canis familiaris 30616 R-CFA-1676185 https://reactome.org/PathwayBrowser/#/R-CFA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Canis familiaris 30616 R-CFA-1676206 https://reactome.org/PathwayBrowser/#/R-CFA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Canis familiaris 30616 R-CFA-1678923 https://reactome.org/PathwayBrowser/#/R-CFA-1678923 TLR folding by chaperones GP96 and CNPY3 IEA Canis familiaris 30616 R-CFA-1678944 https://reactome.org/PathwayBrowser/#/R-CFA-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Canis familiaris 30616 R-CFA-168053 https://reactome.org/PathwayBrowser/#/R-CFA-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Canis familiaris 30616 R-CFA-168136 https://reactome.org/PathwayBrowser/#/R-CFA-168136 Activated JNKs phosphorylate c-JUN IEA Canis familiaris 30616 R-CFA-168140 https://reactome.org/PathwayBrowser/#/R-CFA-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Canis familiaris 30616 R-CFA-168162 https://reactome.org/PathwayBrowser/#/R-CFA-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Canis familiaris 30616 R-CFA-169905 https://reactome.org/PathwayBrowser/#/R-CFA-169905 ARMS is phosphorylated by active TrkA receptor IEA Canis familiaris 30616 R-CFA-170026 https://reactome.org/PathwayBrowser/#/R-CFA-170026 Protons are translocated from the intermembrane space to the matrix IEA Canis familiaris 30616 R-CFA-170055 https://reactome.org/PathwayBrowser/#/R-CFA-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Canis familiaris 30616 R-CFA-170070 https://reactome.org/PathwayBrowser/#/R-CFA-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Canis familiaris 30616 R-CFA-170076 https://reactome.org/PathwayBrowser/#/R-CFA-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Canis familiaris 30616 R-CFA-170087 https://reactome.org/PathwayBrowser/#/R-CFA-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Canis familiaris 30616 R-CFA-170126 https://reactome.org/PathwayBrowser/#/R-CFA-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Canis familiaris 30616 R-CFA-170676 https://reactome.org/PathwayBrowser/#/R-CFA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Canis familiaris 30616 R-CFA-170843 https://reactome.org/PathwayBrowser/#/R-CFA-170843 TGFBR2 phosphorylates TGFBR1 IEA Canis familiaris 30616 R-CFA-170868 https://reactome.org/PathwayBrowser/#/R-CFA-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Canis familiaris 30616 R-CFA-170977 https://reactome.org/PathwayBrowser/#/R-CFA-170977 FRS2 is phosphorylated by active TrkA receptor IEA Canis familiaris 30616 R-CFA-174079 https://reactome.org/PathwayBrowser/#/R-CFA-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Canis familiaris 30616 R-CFA-174122 https://reactome.org/PathwayBrowser/#/R-CFA-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Canis familiaris 30616 R-CFA-174164 https://reactome.org/PathwayBrowser/#/R-CFA-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Canis familiaris 30616 R-CFA-174174 https://reactome.org/PathwayBrowser/#/R-CFA-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Canis familiaris 30616 R-CFA-174251 https://reactome.org/PathwayBrowser/#/R-CFA-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Canis familiaris 30616 R-CFA-174367 https://reactome.org/PathwayBrowser/#/R-CFA-174367 GCL ligates L-Glu to L-Cys IEA Canis familiaris 30616 R-CFA-174389 https://reactome.org/PathwayBrowser/#/R-CFA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Canis familiaris 30616 R-CFA-174391 https://reactome.org/PathwayBrowser/#/R-CFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Canis familiaris 30616 R-CFA-174392 https://reactome.org/PathwayBrowser/#/R-CFA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Canis familiaris 30616 R-CFA-174394 https://reactome.org/PathwayBrowser/#/R-CFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Canis familiaris 30616 R-CFA-174438 https://reactome.org/PathwayBrowser/#/R-CFA-174438 Formation of the Flap Intermediate on the C-strand IEA Canis familiaris 30616 R-CFA-174439 https://reactome.org/PathwayBrowser/#/R-CFA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Canis familiaris 30616 R-CFA-176116 https://reactome.org/PathwayBrowser/#/R-CFA-176116 Recruitment and activation of Chk1 IEA Canis familiaris 30616 R-CFA-176298 https://reactome.org/PathwayBrowser/#/R-CFA-176298 Activation of claspin IEA Canis familiaris 30616 R-CFA-177157 https://reactome.org/PathwayBrowser/#/R-CFA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Canis familiaris 30616 R-CFA-177275 https://reactome.org/PathwayBrowser/#/R-CFA-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Canis familiaris 30616 R-CFA-177284 https://reactome.org/PathwayBrowser/#/R-CFA-177284 PKA phosphorylates PDE4B IEA Canis familiaris 30616 R-CFA-177930 https://reactome.org/PathwayBrowser/#/R-CFA-177930 GAB1 phosphorylation by EGFR kinase IEA Canis familiaris 30616 R-CFA-177933 https://reactome.org/PathwayBrowser/#/R-CFA-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Canis familiaris 30616 R-CFA-177934 https://reactome.org/PathwayBrowser/#/R-CFA-177934 EGFR autophosphorylation IEA Canis familiaris 30616 R-CFA-177937 https://reactome.org/PathwayBrowser/#/R-CFA-177937 Phosphorylation of EGFR by SRC kinase IEA Canis familiaris 30616 R-CFA-177939 https://reactome.org/PathwayBrowser/#/R-CFA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Canis familiaris 30616 R-CFA-182969 https://reactome.org/PathwayBrowser/#/R-CFA-182969 Phosphorylation of CBL (EGFR:CBL) IEA Canis familiaris 30616 R-CFA-183058 https://reactome.org/PathwayBrowser/#/R-CFA-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Canis familiaris 30616 R-CFA-1855153 https://reactome.org/PathwayBrowser/#/R-CFA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Canis familiaris 30616 R-CFA-1855157 https://reactome.org/PathwayBrowser/#/R-CFA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Canis familiaris 30616 R-CFA-1855158 https://reactome.org/PathwayBrowser/#/R-CFA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Canis familiaris 30616 R-CFA-1855162 https://reactome.org/PathwayBrowser/#/R-CFA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Canis familiaris 30616 R-CFA-1855169 https://reactome.org/PathwayBrowser/#/R-CFA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 30616 R-CFA-1855172 https://reactome.org/PathwayBrowser/#/R-CFA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Canis familiaris 30616 R-CFA-1855176 https://reactome.org/PathwayBrowser/#/R-CFA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Canis familiaris 30616 R-CFA-1855179 https://reactome.org/PathwayBrowser/#/R-CFA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Canis familiaris 30616 R-CFA-1855181 https://reactome.org/PathwayBrowser/#/R-CFA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Canis familiaris 30616 R-CFA-1855182 https://reactome.org/PathwayBrowser/#/R-CFA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Canis familiaris 30616 R-CFA-1855185 https://reactome.org/PathwayBrowser/#/R-CFA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 30616 R-CFA-1855193 https://reactome.org/PathwayBrowser/#/R-CFA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Canis familiaris 30616 R-CFA-1855194 https://reactome.org/PathwayBrowser/#/R-CFA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Canis familiaris 30616 R-CFA-1855197 https://reactome.org/PathwayBrowser/#/R-CFA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 30616 R-CFA-1855206 https://reactome.org/PathwayBrowser/#/R-CFA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 30616 R-CFA-1855207 https://reactome.org/PathwayBrowser/#/R-CFA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Canis familiaris 30616 R-CFA-1855216 https://reactome.org/PathwayBrowser/#/R-CFA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Canis familiaris 30616 R-CFA-1855223 https://reactome.org/PathwayBrowser/#/R-CFA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Canis familiaris 30616 R-CFA-1855224 https://reactome.org/PathwayBrowser/#/R-CFA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Canis familiaris 30616 R-CFA-1855227 https://reactome.org/PathwayBrowser/#/R-CFA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Canis familiaris 30616 R-CFA-1855228 https://reactome.org/PathwayBrowser/#/R-CFA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 30616 R-CFA-1855230 https://reactome.org/PathwayBrowser/#/R-CFA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Canis familiaris 30616 R-CFA-1855233 https://reactome.org/PathwayBrowser/#/R-CFA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Canis familiaris 30616 R-CFA-1861595 https://reactome.org/PathwayBrowser/#/R-CFA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Canis familiaris 30616 R-CFA-186786 https://reactome.org/PathwayBrowser/#/R-CFA-186786 Autophosphorylation of PDGF beta receptors IEA Canis familiaris 30616 R-CFA-186800 https://reactome.org/PathwayBrowser/#/R-CFA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-187520 https://reactome.org/PathwayBrowser/#/R-CFA-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Canis familiaris 30616 R-CFA-187916 https://reactome.org/PathwayBrowser/#/R-CFA-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Canis familiaris 30616 R-CFA-187948 https://reactome.org/PathwayBrowser/#/R-CFA-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Canis familiaris 30616 R-CFA-187949 https://reactome.org/PathwayBrowser/#/R-CFA-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Canis familiaris 30616 R-CFA-187959 https://reactome.org/PathwayBrowser/#/R-CFA-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Canis familiaris 30616 R-CFA-188350 https://reactome.org/PathwayBrowser/#/R-CFA-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Canis familiaris 30616 R-CFA-188390 https://reactome.org/PathwayBrowser/#/R-CFA-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Canis familiaris 30616 R-CFA-190326 https://reactome.org/PathwayBrowser/#/R-CFA-190326 Autocatalytic phosphorylation of FGFR4 IEA Canis familiaris 30616 R-CFA-190385 https://reactome.org/PathwayBrowser/#/R-CFA-190385 Autocatalytic phosphorylation of FGFR3b IEA Canis familiaris 30616 R-CFA-190388 https://reactome.org/PathwayBrowser/#/R-CFA-190388 Autocatalytic phosphorylation of FGFR3c IEA Canis familiaris 30616 R-CFA-190408 https://reactome.org/PathwayBrowser/#/R-CFA-190408 Autocatalytic phosphorylation of FGFR2b IEA Canis familiaris 30616 R-CFA-190413 https://reactome.org/PathwayBrowser/#/R-CFA-190413 Autocatalytic phosphorylation of FGFR2c IEA Canis familiaris 30616 R-CFA-190427 https://reactome.org/PathwayBrowser/#/R-CFA-190427 Autocatalytic phosphorylation of FGFR1b IEA Canis familiaris 30616 R-CFA-190429 https://reactome.org/PathwayBrowser/#/R-CFA-190429 Autocatalytic phosphorylation of FGFR1c IEA Canis familiaris 30616 R-CFA-191062 https://reactome.org/PathwayBrowser/#/R-CFA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Canis familiaris 30616 R-CFA-191380 https://reactome.org/PathwayBrowser/#/R-CFA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Canis familiaris 30616 R-CFA-191414 https://reactome.org/PathwayBrowser/#/R-CFA-191414 MVD decarboxylates MVA5PP to IPPP IEA Canis familiaris 30616 R-CFA-191422 https://reactome.org/PathwayBrowser/#/R-CFA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Canis familiaris 30616 R-CFA-191636 https://reactome.org/PathwayBrowser/#/R-CFA-191636 Phosphorylation of Cx43 by c-src IEA Canis familiaris 30616 R-CFA-192137 https://reactome.org/PathwayBrowser/#/R-CFA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 30616 R-CFA-193362 https://reactome.org/PathwayBrowser/#/R-CFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-193401 https://reactome.org/PathwayBrowser/#/R-CFA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 30616 R-CFA-193407 https://reactome.org/PathwayBrowser/#/R-CFA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 30616 R-CFA-193424 https://reactome.org/PathwayBrowser/#/R-CFA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 30616 R-CFA-193703 https://reactome.org/PathwayBrowser/#/R-CFA-193703 IKKbeta is activated IEA Canis familiaris 30616 R-CFA-193705 https://reactome.org/PathwayBrowser/#/R-CFA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Canis familiaris 30616 R-CFA-193711 https://reactome.org/PathwayBrowser/#/R-CFA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 30616 R-CFA-193727 https://reactome.org/PathwayBrowser/#/R-CFA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 30616 R-CFA-193743 https://reactome.org/PathwayBrowser/#/R-CFA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 30616 R-CFA-193766 https://reactome.org/PathwayBrowser/#/R-CFA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 30616 R-CFA-194153 https://reactome.org/PathwayBrowser/#/R-CFA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-195275 https://reactome.org/PathwayBrowser/#/R-CFA-195275 Phosphorylation of APC component of the destruction complex IEA Canis familiaris 30616 R-CFA-195283 https://reactome.org/PathwayBrowser/#/R-CFA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Canis familiaris 30616 R-CFA-195287 https://reactome.org/PathwayBrowser/#/R-CFA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Canis familiaris 30616 R-CFA-195300 https://reactome.org/PathwayBrowser/#/R-CFA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Canis familiaris 30616 R-CFA-195318 https://reactome.org/PathwayBrowser/#/R-CFA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Canis familiaris 30616 R-CFA-1963581 https://reactome.org/PathwayBrowser/#/R-CFA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Canis familiaris 30616 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 30616 R-CFA-1963586 https://reactome.org/PathwayBrowser/#/R-CFA-1963586 SRC family kinases phosphorylate ERBB2 IEA Canis familiaris 30616 R-CFA-196753 https://reactome.org/PathwayBrowser/#/R-CFA-196753 2xPPCS ligates PPanK with Cys IEA Canis familiaris 30616 R-CFA-196754 https://reactome.org/PathwayBrowser/#/R-CFA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Canis familiaris 30616 R-CFA-196761 https://reactome.org/PathwayBrowser/#/R-CFA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Canis familiaris 30616 R-CFA-196773 https://reactome.org/PathwayBrowser/#/R-CFA-196773 COASY phosphorylates DP-CoA IEA Canis familiaris 30616 R-CFA-196857 https://reactome.org/PathwayBrowser/#/R-CFA-196857 PANK2 phosphorylates PanK IEA Canis familiaris 30616 R-CFA-196929 https://reactome.org/PathwayBrowser/#/R-CFA-196929 FLAD1 phosphorylates FMN IEA Canis familiaris 30616 R-CFA-196964 https://reactome.org/PathwayBrowser/#/R-CFA-196964 RFK:Mg2+ phosphorylates RIB IEA Canis familiaris 30616 R-CFA-197198 https://reactome.org/PathwayBrowser/#/R-CFA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Canis familiaris 30616 R-CFA-197235 https://reactome.org/PathwayBrowser/#/R-CFA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 30616 R-CFA-197271 https://reactome.org/PathwayBrowser/#/R-CFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Canis familiaris 30616 R-CFA-197958 https://reactome.org/PathwayBrowser/#/R-CFA-197958 FPGS-2 transforms THF to THFPG IEA Canis familiaris 30616 R-CFA-198266 https://reactome.org/PathwayBrowser/#/R-CFA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Canis familiaris 30616 R-CFA-198314 https://reactome.org/PathwayBrowser/#/R-CFA-198314 DAG stimulates protein kinase C-delta IEA Canis familiaris 30616 R-CFA-198669 https://reactome.org/PathwayBrowser/#/R-CFA-198669 p38MAPK phosphorylates MSK1 IEA Canis familiaris 30616 R-CFA-198746 https://reactome.org/PathwayBrowser/#/R-CFA-198746 ERK1/2/5 activate RSK1/2/3 IEA Canis familiaris 30616 R-CFA-198756 https://reactome.org/PathwayBrowser/#/R-CFA-198756 ERK1/2 phosphorylates MSK1 IEA Canis familiaris 30616 R-CFA-199203 https://reactome.org/PathwayBrowser/#/R-CFA-199203 PANK1/3 phosphorylate PanK IEA Canis familiaris 30616 R-CFA-199895 https://reactome.org/PathwayBrowser/#/R-CFA-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Canis familiaris 30616 R-CFA-199910 https://reactome.org/PathwayBrowser/#/R-CFA-199910 MSK1 activates ATF1 IEA Canis familiaris 30616 R-CFA-199935 https://reactome.org/PathwayBrowser/#/R-CFA-199935 MSK1 activates CREB IEA Canis familiaris 30616 R-CFA-200318 https://reactome.org/PathwayBrowser/#/R-CFA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Canis familiaris 30616 R-CFA-200326 https://reactome.org/PathwayBrowser/#/R-CFA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Canis familiaris 30616 R-CFA-200421 https://reactome.org/PathwayBrowser/#/R-CFA-200421 Activation of cytosolic AMPK by phosphorylation IEA Canis familiaris 30616 R-CFA-200423 https://reactome.org/PathwayBrowser/#/R-CFA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Canis familiaris 30616 R-CFA-200474 https://reactome.org/PathwayBrowser/#/R-CFA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 30616 R-CFA-200512 https://reactome.org/PathwayBrowser/#/R-CFA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 30616 R-CFA-200555 https://reactome.org/PathwayBrowser/#/R-CFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Canis familiaris 30616 R-CFA-200681 https://reactome.org/PathwayBrowser/#/R-CFA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Canis familiaris 30616 R-CFA-200682 https://reactome.org/PathwayBrowser/#/R-CFA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Canis familiaris 30616 R-CFA-200711 https://reactome.org/PathwayBrowser/#/R-CFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Canis familiaris 30616 R-CFA-201035 https://reactome.org/PathwayBrowser/#/R-CFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Canis familiaris 30616 R-CFA-201443 https://reactome.org/PathwayBrowser/#/R-CFA-201443 Type II receptor phosphorylates type I receptor IEA Canis familiaris 30616 R-CFA-201476 https://reactome.org/PathwayBrowser/#/R-CFA-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Canis familiaris 30616 R-CFA-201510 https://reactome.org/PathwayBrowser/#/R-CFA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Canis familiaris 30616 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 30616 R-CFA-201677 https://reactome.org/PathwayBrowser/#/R-CFA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Canis familiaris 30616 R-CFA-201717 https://reactome.org/PathwayBrowser/#/R-CFA-201717 CSNK2-mediated phosphorylation of DVL IEA Canis familiaris 30616 R-CFA-202165 https://reactome.org/PathwayBrowser/#/R-CFA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Canis familiaris 30616 R-CFA-202168 https://reactome.org/PathwayBrowser/#/R-CFA-202168 Phosphorylation of ZAP-70 by Lck IEA Canis familiaris 30616 R-CFA-202174 https://reactome.org/PathwayBrowser/#/R-CFA-202174 Activation of ZAP-70 IEA Canis familiaris 30616 R-CFA-202216 https://reactome.org/PathwayBrowser/#/R-CFA-202216 Phosphorylation of SLP-76 IEA Canis familiaris 30616 R-CFA-202222 https://reactome.org/PathwayBrowser/#/R-CFA-202222 Phosphorylation of PKC theta IEA Canis familiaris 30616 R-CFA-202233 https://reactome.org/PathwayBrowser/#/R-CFA-202233 Inactivation of Lck by Csk IEA Canis familiaris 30616 R-CFA-202245 https://reactome.org/PathwayBrowser/#/R-CFA-202245 Phosphorylation of TBSMs in LAT IEA Canis familiaris 30616 R-CFA-202248 https://reactome.org/PathwayBrowser/#/R-CFA-202248 Phosphorylation of PLC-gamma1 IEA Canis familiaris 30616 R-CFA-202291 https://reactome.org/PathwayBrowser/#/R-CFA-202291 Activation of Lck IEA Canis familiaris 30616 R-CFA-202307 https://reactome.org/PathwayBrowser/#/R-CFA-202307 Change of PKC theta conformation IEA Canis familiaris 30616 R-CFA-202365 https://reactome.org/PathwayBrowser/#/R-CFA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-202437 https://reactome.org/PathwayBrowser/#/R-CFA-202437 Phosphorylation of CARMA1 IEA Canis familiaris 30616 R-CFA-202459 https://reactome.org/PathwayBrowser/#/R-CFA-202459 Phosphorylation of Bcl10 IEA Canis familiaris 30616 R-CFA-202500 https://reactome.org/PathwayBrowser/#/R-CFA-202500 Activation of IKK complex IEA Canis familiaris 30616 R-CFA-202510 https://reactome.org/PathwayBrowser/#/R-CFA-202510 Activation of TAK1-TAB2 complex IEA Canis familiaris 30616 R-CFA-202541 https://reactome.org/PathwayBrowser/#/R-CFA-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Canis familiaris 30616 R-CFA-2028284 https://reactome.org/PathwayBrowser/#/R-CFA-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Canis familiaris 30616 R-CFA-2028555 https://reactome.org/PathwayBrowser/#/R-CFA-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Canis familiaris 30616 R-CFA-2028583 https://reactome.org/PathwayBrowser/#/R-CFA-2028583 Phosphorylation of YAP by LATS2 IEA Canis familiaris 30616 R-CFA-2028589 https://reactome.org/PathwayBrowser/#/R-CFA-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Canis familiaris 30616 R-CFA-2028591 https://reactome.org/PathwayBrowser/#/R-CFA-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Canis familiaris 30616 R-CFA-2028598 https://reactome.org/PathwayBrowser/#/R-CFA-2028598 Phosphorylation of YAP by LATS1 IEA Canis familiaris 30616 R-CFA-2028629 https://reactome.org/PathwayBrowser/#/R-CFA-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Canis familiaris 30616 R-CFA-2028635 https://reactome.org/PathwayBrowser/#/R-CFA-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Canis familiaris 30616 R-CFA-2028661 https://reactome.org/PathwayBrowser/#/R-CFA-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Canis familiaris 30616 R-CFA-2028670 https://reactome.org/PathwayBrowser/#/R-CFA-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Canis familiaris 30616 R-CFA-2028673 https://reactome.org/PathwayBrowser/#/R-CFA-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Canis familiaris 30616 R-CFA-2028675 https://reactome.org/PathwayBrowser/#/R-CFA-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Canis familiaris 30616 R-CFA-2028679 https://reactome.org/PathwayBrowser/#/R-CFA-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Canis familiaris 30616 R-CFA-2029268 https://reactome.org/PathwayBrowser/#/R-CFA-2029268 Phosphorylation and activation of PLCG IEA Canis familiaris 30616 R-CFA-2029271 https://reactome.org/PathwayBrowser/#/R-CFA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-2029453 https://reactome.org/PathwayBrowser/#/R-CFA-2029453 Phosphorylation of VAV IEA Canis familiaris 30616 R-CFA-2029454 https://reactome.org/PathwayBrowser/#/R-CFA-2029454 Autophosphorylation of PAK1 IEA Canis familiaris 30616 R-CFA-2029459 https://reactome.org/PathwayBrowser/#/R-CFA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Canis familiaris 30616 R-CFA-2029460 https://reactome.org/PathwayBrowser/#/R-CFA-2029460 PAK1 phosphorylates LIMK1 IEA Canis familiaris 30616 R-CFA-2029466 https://reactome.org/PathwayBrowser/#/R-CFA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Canis familiaris 30616 R-CFA-2029469 https://reactome.org/PathwayBrowser/#/R-CFA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Canis familiaris 30616 R-CFA-2029473 https://reactome.org/PathwayBrowser/#/R-CFA-2029473 Branching and elongation of mother and daughter filaments IEA Canis familiaris 30616 R-CFA-2029476 https://reactome.org/PathwayBrowser/#/R-CFA-2029476 Role of myosins in phagosome formation IEA Canis familiaris 30616 R-CFA-203070 https://reactome.org/PathwayBrowser/#/R-CFA-203070 Association of profilin with monomeric actin IEA Canis familiaris 30616 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 30616 R-CFA-2046085 https://reactome.org/PathwayBrowser/#/R-CFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Canis familiaris 30616 R-CFA-2046087 https://reactome.org/PathwayBrowser/#/R-CFA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Canis familiaris 30616 R-CFA-2046093 https://reactome.org/PathwayBrowser/#/R-CFA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Canis familiaris 30616 R-CFA-2046098 https://reactome.org/PathwayBrowser/#/R-CFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Canis familiaris 30616 R-CFA-205075 https://reactome.org/PathwayBrowser/#/R-CFA-205075 JNK phosphorylates BIM, BAD and other targets IEA Canis familiaris 30616 R-CFA-205136 https://reactome.org/PathwayBrowser/#/R-CFA-205136 GTP-bound RAC contributes to JNK activation IEA Canis familiaris 30616 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 30616 R-CFA-2060328 https://reactome.org/PathwayBrowser/#/R-CFA-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Canis familiaris 30616 R-CFA-209087 https://reactome.org/PathwayBrowser/#/R-CFA-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Canis familiaris 30616 R-CFA-210291 https://reactome.org/PathwayBrowser/#/R-CFA-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Canis familiaris 30616 R-CFA-212710 https://reactome.org/PathwayBrowser/#/R-CFA-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Canis familiaris 30616 R-CFA-2130194 https://reactome.org/PathwayBrowser/#/R-CFA-2130194 ABL phosphorylates WAVEs IEA Canis familiaris 30616 R-CFA-216723 https://reactome.org/PathwayBrowser/#/R-CFA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Canis familiaris 30616 R-CFA-216757 https://reactome.org/PathwayBrowser/#/R-CFA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Canis familiaris 30616 R-CFA-2176475 https://reactome.org/PathwayBrowser/#/R-CFA-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Canis familiaris 30616 R-CFA-2197690 https://reactome.org/PathwayBrowser/#/R-CFA-2197690 Detachment of WASP/WAVE IEA Canis familiaris 30616 R-CFA-2197698 https://reactome.org/PathwayBrowser/#/R-CFA-2197698 Src phosphorylate WASP,N-WASP IEA Canis familiaris 30616 R-CFA-2213248 https://reactome.org/PathwayBrowser/#/R-CFA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Canis familiaris 30616 R-CFA-2214351 https://reactome.org/PathwayBrowser/#/R-CFA-2214351 PLK1 phosphorylates GORASP1 IEA Canis familiaris 30616 R-CFA-2267372 https://reactome.org/PathwayBrowser/#/R-CFA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Canis familiaris 30616 R-CFA-2294580 https://reactome.org/PathwayBrowser/#/R-CFA-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Canis familiaris 30616 R-CFA-2294600 https://reactome.org/PathwayBrowser/#/R-CFA-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Canis familiaris 30616 R-CFA-2316434 https://reactome.org/PathwayBrowser/#/R-CFA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-2395412 https://reactome.org/PathwayBrowser/#/R-CFA-2395412 Phosphorylation of SYK IEA Canis familiaris 30616 R-CFA-2395801 https://reactome.org/PathwayBrowser/#/R-CFA-2395801 Phosphorylation of LAT by p-SYK IEA Canis familiaris 30616 R-CFA-2396594 https://reactome.org/PathwayBrowser/#/R-CFA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Canis familiaris 30616 R-CFA-2404193 https://reactome.org/PathwayBrowser/#/R-CFA-2404193 IGF1R phosphorylates SHC1 IEA Canis familiaris 30616 R-CFA-2404199 https://reactome.org/PathwayBrowser/#/R-CFA-2404199 IGF1,2:IGF1R autophosphorylates IEA Canis familiaris 30616 R-CFA-2408551 https://reactome.org/PathwayBrowser/#/R-CFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Canis familiaris 30616 R-CFA-2422927 https://reactome.org/PathwayBrowser/#/R-CFA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Canis familiaris 30616 R-CFA-2424480 https://reactome.org/PathwayBrowser/#/R-CFA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-2424484 https://reactome.org/PathwayBrowser/#/R-CFA-2424484 Phosphorylation of BTK by p-SYK IEA Canis familiaris 30616 R-CFA-2424486 https://reactome.org/PathwayBrowser/#/R-CFA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Canis familiaris 30616 R-CFA-2424487 https://reactome.org/PathwayBrowser/#/R-CFA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Canis familiaris 30616 R-CFA-2428926 https://reactome.org/PathwayBrowser/#/R-CFA-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Canis familiaris 30616 R-CFA-2430535 https://reactome.org/PathwayBrowser/#/R-CFA-2430535 MASTL phosphorylates ENSA IEA Canis familiaris 30616 R-CFA-2454208 https://reactome.org/PathwayBrowser/#/R-CFA-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Canis familiaris 30616 R-CFA-2466068 https://reactome.org/PathwayBrowser/#/R-CFA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Canis familiaris 30616 R-CFA-2468287 https://reactome.org/PathwayBrowser/#/R-CFA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Canis familiaris 30616 R-CFA-2468293 https://reactome.org/PathwayBrowser/#/R-CFA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Canis familiaris 30616 R-CFA-2529020 https://reactome.org/PathwayBrowser/#/R-CFA-2529020 CK2 phosphorylates condensin I subunits IEA Canis familiaris 30616 R-CFA-2562526 https://reactome.org/PathwayBrowser/#/R-CFA-2562526 PLK1 phosphorylates OPTN IEA Canis familiaris 30616 R-CFA-2574840 https://reactome.org/PathwayBrowser/#/R-CFA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Canis familiaris 30616 R-CFA-2581474 https://reactome.org/PathwayBrowser/#/R-CFA-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Canis familiaris 30616 R-CFA-265682 https://reactome.org/PathwayBrowser/#/R-CFA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Canis familiaris 30616 R-CFA-265783 https://reactome.org/PathwayBrowser/#/R-CFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-266082 https://reactome.org/PathwayBrowser/#/R-CFA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Canis familiaris 30616 R-CFA-2682349 https://reactome.org/PathwayBrowser/#/R-CFA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Canis familiaris 30616 R-CFA-2730833 https://reactome.org/PathwayBrowser/#/R-CFA-2730833 Phosphorylation of TEC kinases by p-SYK IEA Canis familiaris 30616 R-CFA-2730835 https://reactome.org/PathwayBrowser/#/R-CFA-2730835 Autophosphorylation of PKC-theta IEA Canis familiaris 30616 R-CFA-2730841 https://reactome.org/PathwayBrowser/#/R-CFA-2730841 Phosphorylation and activation of VAV IEA Canis familiaris 30616 R-CFA-2730843 https://reactome.org/PathwayBrowser/#/R-CFA-2730843 Phosphorylation of LAT by p-SYK IEA Canis familiaris 30616 R-CFA-2730851 https://reactome.org/PathwayBrowser/#/R-CFA-2730851 Phosphorylation of SLP-76 by p-SYK IEA Canis familiaris 30616 R-CFA-2730856 https://reactome.org/PathwayBrowser/#/R-CFA-2730856 Autophosphorylation of PAK IEA Canis familiaris 30616 R-CFA-2730858 https://reactome.org/PathwayBrowser/#/R-CFA-2730858 Autophosphorylation of BTK/ITK IEA Canis familiaris 30616 R-CFA-2730862 https://reactome.org/PathwayBrowser/#/R-CFA-2730862 Autophosphorylation of LYN kinase IEA Canis familiaris 30616 R-CFA-2730863 https://reactome.org/PathwayBrowser/#/R-CFA-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Canis familiaris 30616 R-CFA-2730868 https://reactome.org/PathwayBrowser/#/R-CFA-2730868 Phosphorylation of MEK7 by MEKK1 IEA Canis familiaris 30616 R-CFA-2730870 https://reactome.org/PathwayBrowser/#/R-CFA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Canis familiaris 30616 R-CFA-2730876 https://reactome.org/PathwayBrowser/#/R-CFA-2730876 Phosphorylation of IKK-beta by TAK1 IEA Canis familiaris 30616 R-CFA-2730882 https://reactome.org/PathwayBrowser/#/R-CFA-2730882 Phosphorylation of PKC-theta IEA Canis familiaris 30616 R-CFA-2730884 https://reactome.org/PathwayBrowser/#/R-CFA-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Canis familiaris 30616 R-CFA-2730886 https://reactome.org/PathwayBrowser/#/R-CFA-2730886 Phosphorylation of SHC by SYK kinase IEA Canis familiaris 30616 R-CFA-2730896 https://reactome.org/PathwayBrowser/#/R-CFA-2730896 Phosphorylation of MEK4 by MEKK1 IEA Canis familiaris 30616 R-CFA-2730900 https://reactome.org/PathwayBrowser/#/R-CFA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Canis familiaris 30616 R-CFA-2730904 https://reactome.org/PathwayBrowser/#/R-CFA-2730904 Auto-ubiquitination of TRAF6 IEA Canis familiaris 30616 R-CFA-2855020 https://reactome.org/PathwayBrowser/#/R-CFA-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Canis familiaris 30616 R-CFA-2984220 https://reactome.org/PathwayBrowser/#/R-CFA-2984220 CDK1:CCNB phosphorylates NEK9 IEA Canis familiaris 30616 R-CFA-2984226 https://reactome.org/PathwayBrowser/#/R-CFA-2984226 PLK1 phosphorylates NEK9 IEA Canis familiaris 30616 R-CFA-2984258 https://reactome.org/PathwayBrowser/#/R-CFA-2984258 NEK9 phosphorylates NEK6/NEK7 IEA Canis familiaris 30616 R-CFA-2990833 https://reactome.org/PathwayBrowser/#/R-CFA-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Canis familiaris 30616 R-CFA-2990880 https://reactome.org/PathwayBrowser/#/R-CFA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Canis familiaris 30616 R-CFA-2990882 https://reactome.org/PathwayBrowser/#/R-CFA-2990882 CDK1 phosphorylates NUP98 IEA Canis familiaris 30616 R-CFA-2993447 https://reactome.org/PathwayBrowser/#/R-CFA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Canis familiaris 30616 R-CFA-2993799 https://reactome.org/PathwayBrowser/#/R-CFA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Canis familiaris 30616 R-CFA-2993802 https://reactome.org/PathwayBrowser/#/R-CFA-2993802 HLCS biotinylates PC:Mn2+ IEA Canis familiaris 30616 R-CFA-2993814 https://reactome.org/PathwayBrowser/#/R-CFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Canis familiaris 30616 R-CFA-2993898 https://reactome.org/PathwayBrowser/#/R-CFA-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Canis familiaris 30616 R-CFA-3000310 https://reactome.org/PathwayBrowser/#/R-CFA-3000310 AURKA phosphorylates PLK1 IEA Canis familiaris 30616 R-CFA-3000327 https://reactome.org/PathwayBrowser/#/R-CFA-3000327 PLK1 phosphorylates BORA IEA Canis familiaris 30616 R-CFA-3095901 https://reactome.org/PathwayBrowser/#/R-CFA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Canis familiaris 30616 R-CFA-3132737 https://reactome.org/PathwayBrowser/#/R-CFA-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Canis familiaris 30616 R-CFA-3159253 https://reactome.org/PathwayBrowser/#/R-CFA-3159253 MMAB adenosylates cob(I)alamin IEA Canis familiaris 30616 R-CFA-3222006 https://reactome.org/PathwayBrowser/#/R-CFA-3222006 STK11 (LKB1) phosphorylates NUAK1 IEA Canis familiaris 30616 R-CFA-3222020 https://reactome.org/PathwayBrowser/#/R-CFA-3222020 NUAK1 phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-3228469 https://reactome.org/PathwayBrowser/#/R-CFA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Canis familiaris 30616 R-CFA-3249379 https://reactome.org/PathwayBrowser/#/R-CFA-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Canis familiaris 30616 R-CFA-3371422 https://reactome.org/PathwayBrowser/#/R-CFA-3371422 ATP hydrolysis by HSP70 IEA Canis familiaris 30616 R-CFA-3371435 https://reactome.org/PathwayBrowser/#/R-CFA-3371435 Constitutive phosphorylation by GSK3 IEA Canis familiaris 30616 R-CFA-3371531 https://reactome.org/PathwayBrowser/#/R-CFA-3371531 Constitutive phosphorylation by pERK1/2 IEA Canis familiaris 30616 R-CFA-3371590 https://reactome.org/PathwayBrowser/#/R-CFA-3371590 HSP70 binds to HSP40:nascent protein IEA Canis familiaris 30616 R-CFA-349426 https://reactome.org/PathwayBrowser/#/R-CFA-349426 Phosphorylation of MDM4 by CHEK2 IEA Canis familiaris 30616 R-CFA-349444 https://reactome.org/PathwayBrowser/#/R-CFA-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Canis familiaris 30616 R-CFA-349455 https://reactome.org/PathwayBrowser/#/R-CFA-349455 Phosphorylation of MDM4 by ATM IEA Canis familiaris 30616 R-CFA-354073 https://reactome.org/PathwayBrowser/#/R-CFA-354073 Autophosphorylation of PTK2 at Y397 IEA Canis familiaris 30616 R-CFA-354124 https://reactome.org/PathwayBrowser/#/R-CFA-354124 Phosphorylation of pPTK2 by SRC IEA Canis familiaris 30616 R-CFA-372693 https://reactome.org/PathwayBrowser/#/R-CFA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Canis familiaris 30616 R-CFA-373747 https://reactome.org/PathwayBrowser/#/R-CFA-373747 Phosphorylation of nephrin by FYN IEA Canis familiaris 30616 R-CFA-373750 https://reactome.org/PathwayBrowser/#/R-CFA-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Canis familiaris 30616 R-CFA-374664 https://reactome.org/PathwayBrowser/#/R-CFA-374664 Phosphorylation and activation of Ezrin IEA Canis familiaris 30616 R-CFA-374701 https://reactome.org/PathwayBrowser/#/R-CFA-374701 Phosphorylation of DCC by Fyn IEA Canis familiaris 30616 R-CFA-375160 https://reactome.org/PathwayBrowser/#/R-CFA-375160 NCAM1 binds to ATP IEA Canis familiaris 30616 R-CFA-3772436 https://reactome.org/PathwayBrowser/#/R-CFA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Canis familiaris 30616 R-CFA-377640 https://reactome.org/PathwayBrowser/#/R-CFA-377640 Autophosphorylation of SRC IEA Canis familiaris 30616 R-CFA-3788705 https://reactome.org/PathwayBrowser/#/R-CFA-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Canis familiaris 30616 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 30616 R-CFA-380272 https://reactome.org/PathwayBrowser/#/R-CFA-380272 Plk1-mediated phosphorylation of Nlp IEA Canis familiaris 30616 R-CFA-380278 https://reactome.org/PathwayBrowser/#/R-CFA-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Canis familiaris 30616 R-CFA-380780 https://reactome.org/PathwayBrowser/#/R-CFA-380780 Activation of Src IEA Canis familiaris 30616 R-CFA-380927 https://reactome.org/PathwayBrowser/#/R-CFA-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Canis familiaris 30616 R-CFA-381091 https://reactome.org/PathwayBrowser/#/R-CFA-381091 IRE1 dimer autophosphorylates IEA Canis familiaris 30616 R-CFA-381111 https://reactome.org/PathwayBrowser/#/R-CFA-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Canis familiaris 30616 R-CFA-382553 https://reactome.org/PathwayBrowser/#/R-CFA-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Canis familiaris 30616 R-CFA-382560 https://reactome.org/PathwayBrowser/#/R-CFA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Canis familiaris 30616 R-CFA-382575 https://reactome.org/PathwayBrowser/#/R-CFA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Canis familiaris 30616 R-CFA-383190 https://reactome.org/PathwayBrowser/#/R-CFA-383190 HCO3- transport through ion channel IEA Canis familiaris 30616 R-CFA-3857329 https://reactome.org/PathwayBrowser/#/R-CFA-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Canis familiaris 30616 R-CFA-388831 https://reactome.org/PathwayBrowser/#/R-CFA-388831 Phosphorylation of CD28 IEA Canis familiaris 30616 R-CFA-388833 https://reactome.org/PathwayBrowser/#/R-CFA-388833 Phosphorylation of CTLA-4 IEA Canis familiaris 30616 R-CFA-389083 https://reactome.org/PathwayBrowser/#/R-CFA-389083 Autophosphorylation of PDGF alpha receptors IEA Canis familiaris 30616 R-CFA-389086 https://reactome.org/PathwayBrowser/#/R-CFA-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Canis familiaris 30616 R-CFA-389158 https://reactome.org/PathwayBrowser/#/R-CFA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-389354 https://reactome.org/PathwayBrowser/#/R-CFA-389354 Activation of Vav1 IEA Canis familiaris 30616 R-CFA-389622 https://reactome.org/PathwayBrowser/#/R-CFA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 30616 R-CFA-389632 https://reactome.org/PathwayBrowser/#/R-CFA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 30616 R-CFA-389652 https://reactome.org/PathwayBrowser/#/R-CFA-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Canis familiaris 30616 R-CFA-389762 https://reactome.org/PathwayBrowser/#/R-CFA-389762 Phosphorylation of PD-1 IEA Canis familiaris 30616 R-CFA-390593 https://reactome.org/PathwayBrowser/#/R-CFA-390593 ATP Hydrolysis By Myosin IEA Canis familiaris 30616 R-CFA-390598 https://reactome.org/PathwayBrowser/#/R-CFA-390598 Myosin Binds ATP IEA Canis familiaris 30616 R-CFA-392300 https://reactome.org/PathwayBrowser/#/R-CFA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-392530 https://reactome.org/PathwayBrowser/#/R-CFA-392530 p-S400-Cot phosphorylates NIK IEA Canis familiaris 30616 R-CFA-3928578 https://reactome.org/PathwayBrowser/#/R-CFA-3928578 EPH receptors autophosphorylate IEA Canis familiaris 30616 R-CFA-3928595 https://reactome.org/PathwayBrowser/#/R-CFA-3928595 N-WASP binds ARP2/3 and G-actin IEA Canis familiaris 30616 R-CFA-3928604 https://reactome.org/PathwayBrowser/#/R-CFA-3928604 SFKs phosphorylate VAV2,3 IEA Canis familiaris 30616 R-CFA-3928620 https://reactome.org/PathwayBrowser/#/R-CFA-3928620 PAK1 autophosphorylates IEA Canis familiaris 30616 R-CFA-3928625 https://reactome.org/PathwayBrowser/#/R-CFA-3928625 PAKs autophosphorylate IEA Canis familiaris 30616 R-CFA-3928627 https://reactome.org/PathwayBrowser/#/R-CFA-3928627 EPHB phosphorylates TIAM1 IEA Canis familiaris 30616 R-CFA-3928640 https://reactome.org/PathwayBrowser/#/R-CFA-3928640 PAKs phosphorylate MLC IEA Canis familiaris 30616 R-CFA-3928654 https://reactome.org/PathwayBrowser/#/R-CFA-3928654 Clathrin internalises EPH:EFN complexes IEA Canis familiaris 30616 R-CFA-399939 https://reactome.org/PathwayBrowser/#/R-CFA-399939 Autophosphorylation of PAK IEA Canis familiaris 30616 R-CFA-399944 https://reactome.org/PathwayBrowser/#/R-CFA-399944 Phosphorylation of CRMPs by Cdk5 IEA Canis familiaris 30616 R-CFA-399947 https://reactome.org/PathwayBrowser/#/R-CFA-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Canis familiaris 30616 R-CFA-399951 https://reactome.org/PathwayBrowser/#/R-CFA-399951 Phosphorylation of CRMPs by GSK3beta IEA Canis familiaris 30616 R-CFA-399952 https://reactome.org/PathwayBrowser/#/R-CFA-399952 Phosphorylation of LIMK-1 by PAK IEA Canis familiaris 30616 R-CFA-399978 https://reactome.org/PathwayBrowser/#/R-CFA-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Canis familiaris 30616 R-CFA-4085028 https://reactome.org/PathwayBrowser/#/R-CFA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Canis familiaris 30616 R-CFA-4086410 https://reactome.org/PathwayBrowser/#/R-CFA-4086410 CDK1 phosphorylates BORA IEA Canis familiaris 30616 R-CFA-4088024 https://reactome.org/PathwayBrowser/#/R-CFA-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Canis familiaris 30616 R-CFA-4088134 https://reactome.org/PathwayBrowser/#/R-CFA-4088134 PLK1 phosphorylates FOXM1 IEA Canis familiaris 30616 R-CFA-416320 https://reactome.org/PathwayBrowser/#/R-CFA-416320 Trafficking of GluR1-containing AMPA receptors IEA Canis familiaris 30616 R-CFA-416639 https://reactome.org/PathwayBrowser/#/R-CFA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Canis familiaris 30616 R-CFA-4167511 https://reactome.org/PathwayBrowser/#/R-CFA-4167511 HLCS biotinylates ACACB IEA Canis familiaris 30616 R-CFA-416985 https://reactome.org/PathwayBrowser/#/R-CFA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Canis familiaris 30616 R-CFA-417825 https://reactome.org/PathwayBrowser/#/R-CFA-417825 P2Y11 receptor can bind to ATP IEA Canis familiaris 30616 R-CFA-417927 https://reactome.org/PathwayBrowser/#/R-CFA-417927 P2Y2 receptor binds ATP and UTP IEA Canis familiaris 30616 R-CFA-418845 https://reactome.org/PathwayBrowser/#/R-CFA-418845 Activation of caspase-3 IEA Canis familiaris 30616 R-CFA-419490 https://reactome.org/PathwayBrowser/#/R-CFA-419490 Binding of ATP to P2X receptors IEA Canis familiaris 30616 R-CFA-419644 https://reactome.org/PathwayBrowser/#/R-CFA-419644 Transphosphorylation of pLIMK1 IEA Canis familiaris 30616 R-CFA-419646 https://reactome.org/PathwayBrowser/#/R-CFA-419646 SEMA4D interacts with Plexin-B1:Met IEA Canis familiaris 30616 R-CFA-421007 https://reactome.org/PathwayBrowser/#/R-CFA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Canis familiaris 30616 R-CFA-421836 https://reactome.org/PathwayBrowser/#/R-CFA-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Canis familiaris 30616 R-CFA-421879 https://reactome.org/PathwayBrowser/#/R-CFA-421879 Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate TAS Canis familiaris 30616 R-CFA-426240 https://reactome.org/PathwayBrowser/#/R-CFA-426240 DAG kinase produces phosphatidic acid from DAG IEA Canis familiaris 30616 R-CFA-428273 https://reactome.org/PathwayBrowser/#/R-CFA-428273 SPHK1 phosphorylates sphingoid IEA Canis familiaris 30616 R-CFA-428941 https://reactome.org/PathwayBrowser/#/R-CFA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Canis familiaris 30616 R-CFA-428961 https://reactome.org/PathwayBrowser/#/R-CFA-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Canis familiaris 30616 R-CFA-429157 https://reactome.org/PathwayBrowser/#/R-CFA-429157 ABCC4 accumulation of dense granule contents IEA Canis familiaris 30616 R-CFA-429441 https://reactome.org/PathwayBrowser/#/R-CFA-429441 SYK activation by SRC IEA Canis familiaris 30616 R-CFA-429449 https://reactome.org/PathwayBrowser/#/R-CFA-429449 Syk activation leads to SLP-76 activation IEA Canis familiaris 30616 R-CFA-430347 https://reactome.org/PathwayBrowser/#/R-CFA-430347 MigFilin associates with Filamin and F-actin IEA Canis familiaris 30616 R-CFA-432129 https://reactome.org/PathwayBrowser/#/R-CFA-432129 FGR binds and phosphorylates LRP8 IEA Canis familiaris 30616 R-CFA-432148 https://reactome.org/PathwayBrowser/#/R-CFA-432148 Fgr may phosphorylate p38 MAPK IEA Canis familiaris 30616 R-CFA-432232 https://reactome.org/PathwayBrowser/#/R-CFA-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Canis familiaris 30616 R-CFA-432688 https://reactome.org/PathwayBrowser/#/R-CFA-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating IEA Canis familiaris 30616 R-CFA-4332358 https://reactome.org/PathwayBrowser/#/R-CFA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Canis familiaris 30616 R-CFA-4332363 https://reactome.org/PathwayBrowser/#/R-CFA-4332363 Autophosphorylation and activation of CAMK2 IEA Canis familiaris 30616 R-CFA-434382 https://reactome.org/PathwayBrowser/#/R-CFA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Canis familiaris 30616 R-CFA-434836 https://reactome.org/PathwayBrowser/#/R-CFA-434836 Syk/Lck phosphorylate LAT IEA Canis familiaris 30616 R-CFA-435244 https://reactome.org/PathwayBrowser/#/R-CFA-435244 PECAM1 is phosphorylated IEA Canis familiaris 30616 R-CFA-437162 https://reactome.org/PathwayBrowser/#/R-CFA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-4411383 https://reactome.org/PathwayBrowser/#/R-CFA-4411383 NLK phosphorylates TCF/LEF IEA Canis familiaris 30616 R-CFA-4411402 https://reactome.org/PathwayBrowser/#/R-CFA-4411402 Activation of NLK IEA Canis familiaris 30616 R-CFA-4420117 https://reactome.org/PathwayBrowser/#/R-CFA-4420117 VEGFR2 autophosphorylates IEA Canis familiaris 30616 R-CFA-4420121 https://reactome.org/PathwayBrowser/#/R-CFA-4420121 SFKs phosphorylate PLCG1 IEA Canis familiaris 30616 R-CFA-4420128 https://reactome.org/PathwayBrowser/#/R-CFA-4420128 SRC-1 phosphorylates SHB IEA Canis familiaris 30616 R-CFA-4420206 https://reactome.org/PathwayBrowser/#/R-CFA-4420206 Phosphorylation of SRC-1 IEA Canis familiaris 30616 R-CFA-442724 https://reactome.org/PathwayBrowser/#/R-CFA-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Canis familiaris 30616 R-CFA-442749 https://reactome.org/PathwayBrowser/#/R-CFA-442749 CaMKK autophosphorylates in the nucleus IEA Canis familiaris 30616 R-CFA-445072 https://reactome.org/PathwayBrowser/#/R-CFA-445072 Interaction of PAK1 with Rac1-GTP IEA Canis familiaris 30616 R-CFA-445079 https://reactome.org/PathwayBrowser/#/R-CFA-445079 Phosphorylation of L1 by ERK IEA Canis familiaris 30616 R-CFA-445699 https://reactome.org/PathwayBrowser/#/R-CFA-445699 ATP Hydrolysis By Myosin IEA Canis familiaris 30616 R-CFA-445700 https://reactome.org/PathwayBrowser/#/R-CFA-445700 Myosin Binds ATP IEA Canis familiaris 30616 R-CFA-445813 https://reactome.org/PathwayBrowser/#/R-CFA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Canis familiaris 30616 R-CFA-446634 https://reactome.org/PathwayBrowser/#/R-CFA-446634 IRAK4 is activated by autophosphorylation IEA Canis familiaris 30616 R-CFA-446694 https://reactome.org/PathwayBrowser/#/R-CFA-446694 IRAK4 phosphorylates IRAK1 IEA Canis familiaris 30616 R-CFA-446701 https://reactome.org/PathwayBrowser/#/R-CFA-446701 IRAK4-activated IRAK1 autophosphorylates IEA Canis familiaris 30616 R-CFA-447074 https://reactome.org/PathwayBrowser/#/R-CFA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Canis familiaris 30616 R-CFA-448955 https://reactome.org/PathwayBrowser/#/R-CFA-448955 Phosphorylation of MEF2 proteins by p38 IEA Canis familiaris 30616 R-CFA-449911 https://reactome.org/PathwayBrowser/#/R-CFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Canis familiaris 30616 R-CFA-450088 https://reactome.org/PathwayBrowser/#/R-CFA-450088 GLUT1 tetramer binds 4xATP IEA Canis familiaris 30616 R-CFA-450092 https://reactome.org/PathwayBrowser/#/R-CFA-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Canis familiaris 30616 R-CFA-450325 https://reactome.org/PathwayBrowser/#/R-CFA-450325 c-FOS activation by phospho ERK1/2 IEA Canis familiaris 30616 R-CFA-450337 https://reactome.org/PathwayBrowser/#/R-CFA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Canis familiaris 30616 R-CFA-450346 https://reactome.org/PathwayBrowser/#/R-CFA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Canis familiaris 30616 R-CFA-450533 https://reactome.org/PathwayBrowser/#/R-CFA-450533 PKCdelta phosphorylates HuR IEA Canis familiaris 30616 R-CFA-450550 https://reactome.org/PathwayBrowser/#/R-CFA-450550 PKCalpha phosphorylates HuR IEA Canis familiaris 30616 R-CFA-450827 https://reactome.org/PathwayBrowser/#/R-CFA-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Canis familiaris 30616 R-CFA-451942 https://reactome.org/PathwayBrowser/#/R-CFA-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Canis familiaris 30616 R-CFA-452097 https://reactome.org/PathwayBrowser/#/R-CFA-452097 Recruited STAT5 is phosphorylated IEA Canis familiaris 30616 R-CFA-452100 https://reactome.org/PathwayBrowser/#/R-CFA-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Canis familiaris 30616 R-CFA-452122 https://reactome.org/PathwayBrowser/#/R-CFA-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Canis familiaris 30616 R-CFA-453200 https://reactome.org/PathwayBrowser/#/R-CFA-453200 SYK autophosphorylates IEA Canis familiaris 30616 R-CFA-453342 https://reactome.org/PathwayBrowser/#/R-CFA-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Canis familiaris 30616 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 30616 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 30616 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 30616 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 30616 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 30616 R-CFA-504054 https://reactome.org/PathwayBrowser/#/R-CFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Canis familiaris 30616 R-CFA-508040 https://reactome.org/PathwayBrowser/#/R-CFA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Canis familiaris 30616 R-CFA-5082387 https://reactome.org/PathwayBrowser/#/R-CFA-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Canis familiaris 30616 R-CFA-5082405 https://reactome.org/PathwayBrowser/#/R-CFA-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Canis familiaris 30616 R-CFA-508282 https://reactome.org/PathwayBrowser/#/R-CFA-508282 SYK is a substrate for JAK1 IEA Canis familiaris 30616 R-CFA-508308 https://reactome.org/PathwayBrowser/#/R-CFA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Canis familiaris 30616 R-CFA-5138432 https://reactome.org/PathwayBrowser/#/R-CFA-5138432 DVL2 is phosphorylated by PKC IEA Canis familiaris 30616 R-CFA-5195402 https://reactome.org/PathwayBrowser/#/R-CFA-5195402 CDK1 phosphorylates LPIN IEA Canis familiaris 30616 R-CFA-5213464 https://reactome.org/PathwayBrowser/#/R-CFA-5213464 RIPK1 is phosphorylated IEA Canis familiaris 30616 R-CFA-5213466 https://reactome.org/PathwayBrowser/#/R-CFA-5213466 RIPK3 is phosphorylated IEA Canis familiaris 30616 R-CFA-5218640 https://reactome.org/PathwayBrowser/#/R-CFA-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Canis familiaris 30616 R-CFA-5218642 https://reactome.org/PathwayBrowser/#/R-CFA-5218642 PTK2 autophosphorylates IEA Canis familiaris 30616 R-CFA-5218804 https://reactome.org/PathwayBrowser/#/R-CFA-5218804 p38 MAPK activation by VEGFR IEA Canis familiaris 30616 R-CFA-5218805 https://reactome.org/PathwayBrowser/#/R-CFA-5218805 PKC autophosphorylates IEA Canis familiaris 30616 R-CFA-5218806 https://reactome.org/PathwayBrowser/#/R-CFA-5218806 FYN autophosphorylates IEA Canis familiaris 30616 R-CFA-5218809 https://reactome.org/PathwayBrowser/#/R-CFA-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Canis familiaris 30616 R-CFA-5218812 https://reactome.org/PathwayBrowser/#/R-CFA-5218812 FYN phosphorylates PAK2 IEA Canis familiaris 30616 R-CFA-5218814 https://reactome.org/PathwayBrowser/#/R-CFA-5218814 PAK2 autophorylates IEA Canis familiaris 30616 R-CFA-5218819 https://reactome.org/PathwayBrowser/#/R-CFA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-5218820 https://reactome.org/PathwayBrowser/#/R-CFA-5218820 Src kinases phosphorylate VAV IEA Canis familiaris 30616 R-CFA-5218821 https://reactome.org/PathwayBrowser/#/R-CFA-5218821 PDK1 phosphorylates PKC IEA Canis familiaris 30616 R-CFA-5218823 https://reactome.org/PathwayBrowser/#/R-CFA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Canis familiaris 30616 R-CFA-5218826 https://reactome.org/PathwayBrowser/#/R-CFA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Canis familiaris 30616 R-CFA-5218830 https://reactome.org/PathwayBrowser/#/R-CFA-5218830 SRC-1 phosphorylates PTK2-beta IEA Canis familiaris 30616 R-CFA-5218845 https://reactome.org/PathwayBrowser/#/R-CFA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Canis familiaris 30616 R-CFA-5218851 https://reactome.org/PathwayBrowser/#/R-CFA-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Canis familiaris 30616 R-CFA-5218854 https://reactome.org/PathwayBrowser/#/R-CFA-5218854 p-Y420-FYN is phosphorylated on S21 IEA Canis familiaris 30616 R-CFA-5223313 https://reactome.org/PathwayBrowser/#/R-CFA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Canis familiaris 30616 R-CFA-5223317 https://reactome.org/PathwayBrowser/#/R-CFA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Canis familiaris 30616 R-CFA-5229194 https://reactome.org/PathwayBrowser/#/R-CFA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Canis familiaris 30616 R-CFA-5229343 https://reactome.org/PathwayBrowser/#/R-CFA-5229343 AXIN is phosphorylated in the destruction complex IEA Canis familiaris 30616 R-CFA-5244669 https://reactome.org/PathwayBrowser/#/R-CFA-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Canis familiaris 30616 R-CFA-5251942 https://reactome.org/PathwayBrowser/#/R-CFA-5251942 Hikeshi binds HSP70s:ATP IEA Canis familiaris 30616 R-CFA-5251955 https://reactome.org/PathwayBrowser/#/R-CFA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Canis familiaris 30616 R-CFA-5251959 https://reactome.org/PathwayBrowser/#/R-CFA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Canis familiaris 30616 R-CFA-5251989 https://reactome.org/PathwayBrowser/#/R-CFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Canis familiaris 30616 R-CFA-5252041 https://reactome.org/PathwayBrowser/#/R-CFA-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Canis familiaris 30616 R-CFA-5252079 https://reactome.org/PathwayBrowser/#/R-CFA-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Canis familiaris 30616 R-CFA-5339524 https://reactome.org/PathwayBrowser/#/R-CFA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Canis familiaris 30616 R-CFA-5357429 https://reactome.org/PathwayBrowser/#/R-CFA-5357429 AXL autophosphorylates on Y779 and Y821 IEA Canis familiaris 30616 R-CFA-5357472 https://reactome.org/PathwayBrowser/#/R-CFA-5357472 PAK1-3 autophosphorylates IEA Canis familiaris 30616 R-CFA-5357477 https://reactome.org/PathwayBrowser/#/R-CFA-5357477 PAK1-3 phosphorylates VE-cadherin IEA Canis familiaris 30616 R-CFA-5357831 https://reactome.org/PathwayBrowser/#/R-CFA-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Canis familiaris 30616 R-CFA-5358475 https://reactome.org/PathwayBrowser/#/R-CFA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Canis familiaris 30616 R-CFA-5358510 https://reactome.org/PathwayBrowser/#/R-CFA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Canis familiaris 30616 R-CFA-5358518 https://reactome.org/PathwayBrowser/#/R-CFA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Canis familiaris 30616 R-CFA-5358592 https://reactome.org/PathwayBrowser/#/R-CFA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Canis familiaris 30616 R-CFA-5358597 https://reactome.org/PathwayBrowser/#/R-CFA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Canis familiaris 30616 R-CFA-5358599 https://reactome.org/PathwayBrowser/#/R-CFA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Canis familiaris 30616 R-CFA-5358912 https://reactome.org/PathwayBrowser/#/R-CFA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Canis familiaris 30616 R-CFA-5362459 https://reactome.org/PathwayBrowser/#/R-CFA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Canis familiaris 30616 R-CFA-548843 https://reactome.org/PathwayBrowser/#/R-CFA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Canis familiaris 30616 R-CFA-5603114 https://reactome.org/PathwayBrowser/#/R-CFA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Canis familiaris 30616 R-CFA-5607722 https://reactome.org/PathwayBrowser/#/R-CFA-5607722 Active NIK phosphorylates IKKA dimer IEA Canis familiaris 30616 R-CFA-5607726 https://reactome.org/PathwayBrowser/#/R-CFA-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Canis familiaris 30616 R-CFA-5607732 https://reactome.org/PathwayBrowser/#/R-CFA-5607732 K63polyUb-TAK1 autophosphorylates IEA Canis familiaris 30616 R-CFA-5607740 https://reactome.org/PathwayBrowser/#/R-CFA-5607740 PKC-delta phosphorylates CARD9 IEA Canis familiaris 30616 R-CFA-5607742 https://reactome.org/PathwayBrowser/#/R-CFA-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Canis familiaris 30616 R-CFA-5607750 https://reactome.org/PathwayBrowser/#/R-CFA-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Canis familiaris 30616 R-CFA-5607756 https://reactome.org/PathwayBrowser/#/R-CFA-5607756 TRAF6 oligomer autoubiquitinates IEA Canis familiaris 30616 R-CFA-5607757 https://reactome.org/PathwayBrowser/#/R-CFA-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 IEA Canis familiaris 30616 R-CFA-5610720 https://reactome.org/PathwayBrowser/#/R-CFA-5610720 PKA phosphorylates GLI3 IEA Canis familiaris 30616 R-CFA-5610722 https://reactome.org/PathwayBrowser/#/R-CFA-5610722 CK1 phosphorylates p-GLI3 IEA Canis familiaris 30616 R-CFA-5610727 https://reactome.org/PathwayBrowser/#/R-CFA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Canis familiaris 30616 R-CFA-5610732 https://reactome.org/PathwayBrowser/#/R-CFA-5610732 GSK3 phosphorylates p-GLI3 IEA Canis familiaris 30616 R-CFA-5617179 https://reactome.org/PathwayBrowser/#/R-CFA-5617179 PRKACA phosphorylates TNNI3 IEA Canis familiaris 30616 R-CFA-5617182 https://reactome.org/PathwayBrowser/#/R-CFA-5617182 PRKACA phosphorylates PLN IEA Canis familiaris 30616 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 30616 R-CFA-5618085 https://reactome.org/PathwayBrowser/#/R-CFA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Canis familiaris 30616 R-CFA-5618099 https://reactome.org/PathwayBrowser/#/R-CFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Canis familiaris 30616 R-CFA-5618107 https://reactome.org/PathwayBrowser/#/R-CFA-5618107 ATP binding to HSP90 triggers conformation change IEA Canis familiaris 30616 R-CFA-5621355 https://reactome.org/PathwayBrowser/#/R-CFA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Canis familiaris 30616 R-CFA-5621363 https://reactome.org/PathwayBrowser/#/R-CFA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Canis familiaris 30616 R-CFA-5621370 https://reactome.org/PathwayBrowser/#/R-CFA-5621370 SYK autophosphorylates IEA Canis familiaris 30616 R-CFA-5623667 https://reactome.org/PathwayBrowser/#/R-CFA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Canis familiaris 30616 R-CFA-5624473 https://reactome.org/PathwayBrowser/#/R-CFA-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Canis familiaris 30616 R-CFA-5624486 https://reactome.org/PathwayBrowser/#/R-CFA-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Canis familiaris 30616 R-CFA-5624492 https://reactome.org/PathwayBrowser/#/R-CFA-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Canis familiaris 30616 R-CFA-5625784 https://reactome.org/PathwayBrowser/#/R-CFA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Canis familiaris 30616 R-CFA-5626507 https://reactome.org/PathwayBrowser/#/R-CFA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Canis familiaris 30616 R-CFA-5627775 https://reactome.org/PathwayBrowser/#/R-CFA-5627775 Autophosphorylation of PAK1,2,3 IEA Canis familiaris 30616 R-CFA-5635842 https://reactome.org/PathwayBrowser/#/R-CFA-5635842 ULK3 phosphorylates GLI IEA Canis familiaris 30616 R-CFA-5654147 https://reactome.org/PathwayBrowser/#/R-CFA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Canis familiaris 30616 R-CFA-5654149 https://reactome.org/PathwayBrowser/#/R-CFA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Canis familiaris 30616 R-CFA-5654151 https://reactome.org/PathwayBrowser/#/R-CFA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Canis familiaris 30616 R-CFA-5654222 https://reactome.org/PathwayBrowser/#/R-CFA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Canis familiaris 30616 R-CFA-5654397 https://reactome.org/PathwayBrowser/#/R-CFA-5654397 Activated FGFR2 phosphorylates FRS2 IEA Canis familiaris 30616 R-CFA-5654407 https://reactome.org/PathwayBrowser/#/R-CFA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Canis familiaris 30616 R-CFA-5654408 https://reactome.org/PathwayBrowser/#/R-CFA-5654408 Activated FGFR3 phosphorylates FRS2 IEA Canis familiaris 30616 R-CFA-5654418 https://reactome.org/PathwayBrowser/#/R-CFA-5654418 Activated FGFR4 phosphorylates FRS2 IEA Canis familiaris 30616 R-CFA-5654428 https://reactome.org/PathwayBrowser/#/R-CFA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Canis familiaris 30616 R-CFA-5654560 https://reactome.org/PathwayBrowser/#/R-CFA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Canis familiaris 30616 R-CFA-5654562 https://reactome.org/PathwayBrowser/#/R-CFA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Canis familiaris 30616 R-CFA-5654565 https://reactome.org/PathwayBrowser/#/R-CFA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Canis familiaris 30616 R-CFA-5654566 https://reactome.org/PathwayBrowser/#/R-CFA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Canis familiaris 30616 R-CFA-5654575 https://reactome.org/PathwayBrowser/#/R-CFA-5654575 Activated FGFR1 phosphorylates FRS2 IEA Canis familiaris 30616 R-CFA-5654578 https://reactome.org/PathwayBrowser/#/R-CFA-5654578 Activated FGFR1 phosphorylates FRS3 IEA Canis familiaris 30616 R-CFA-5654582 https://reactome.org/PathwayBrowser/#/R-CFA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Canis familiaris 30616 R-CFA-5654587 https://reactome.org/PathwayBrowser/#/R-CFA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Canis familiaris 30616 R-CFA-5654605 https://reactome.org/PathwayBrowser/#/R-CFA-5654605 Activated FGFR2 phosphorylates FRS3 IEA Canis familiaris 30616 R-CFA-5654607 https://reactome.org/PathwayBrowser/#/R-CFA-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Canis familiaris 30616 R-CFA-5654628 https://reactome.org/PathwayBrowser/#/R-CFA-5654628 Activated FGFR3 phosphorylates FRS3 IEA Canis familiaris 30616 R-CFA-5654631 https://reactome.org/PathwayBrowser/#/R-CFA-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Canis familiaris 30616 R-CFA-5654634 https://reactome.org/PathwayBrowser/#/R-CFA-5654634 Activated FGFR3 phosphorylates SHC1 IEA Canis familiaris 30616 R-CFA-5654653 https://reactome.org/PathwayBrowser/#/R-CFA-5654653 Activated FGFR4 phosphorylates FRS3 IEA Canis familiaris 30616 R-CFA-5654655 https://reactome.org/PathwayBrowser/#/R-CFA-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Canis familiaris 30616 R-CFA-5654690 https://reactome.org/PathwayBrowser/#/R-CFA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-5654692 https://reactome.org/PathwayBrowser/#/R-CFA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-5654697 https://reactome.org/PathwayBrowser/#/R-CFA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-5654701 https://reactome.org/PathwayBrowser/#/R-CFA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-5654705 https://reactome.org/PathwayBrowser/#/R-CFA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-5654709 https://reactome.org/PathwayBrowser/#/R-CFA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-5654714 https://reactome.org/PathwayBrowser/#/R-CFA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-5654717 https://reactome.org/PathwayBrowser/#/R-CFA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-5654989 https://reactome.org/PathwayBrowser/#/R-CFA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Canis familiaris 30616 R-CFA-5662466 https://reactome.org/PathwayBrowser/#/R-CFA-5662466 XYLB phosphorylates D-xylulose IEA Canis familiaris 30616 R-CFA-5665751 https://reactome.org/PathwayBrowser/#/R-CFA-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin IEA Canis familiaris 30616 R-CFA-5665767 https://reactome.org/PathwayBrowser/#/R-CFA-5665767 Activated FMNL3 binds G-actin IEA Canis familiaris 30616 R-CFA-5665802 https://reactome.org/PathwayBrowser/#/R-CFA-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Canis familiaris 30616 R-CFA-5665809 https://reactome.org/PathwayBrowser/#/R-CFA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Canis familiaris 30616 R-CFA-5665868 https://reactome.org/PathwayBrowser/#/R-CFA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Canis familiaris 30616 R-CFA-5665982 https://reactome.org/PathwayBrowser/#/R-CFA-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 IEA Canis familiaris 30616 R-CFA-5666001 https://reactome.org/PathwayBrowser/#/R-CFA-5666001 Profilin:G-actin binds MKL1 IEA Canis familiaris 30616 R-CFA-5666160 https://reactome.org/PathwayBrowser/#/R-CFA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Canis familiaris 30616 R-CFA-5668545 https://reactome.org/PathwayBrowser/#/R-CFA-5668545 NIK autophosphorylates on T559 IEA Canis familiaris 30616 R-CFA-5668947 https://reactome.org/PathwayBrowser/#/R-CFA-5668947 PAK1 phosphorylates myosin phosphatase IEA Canis familiaris 30616 R-CFA-5668984 https://reactome.org/PathwayBrowser/#/R-CFA-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Canis familiaris 30616 R-CFA-5669250 https://reactome.org/PathwayBrowser/#/R-CFA-5669250 PAK1 phosphorylates FLNA IEA Canis familiaris 30616 R-CFA-5671749 https://reactome.org/PathwayBrowser/#/R-CFA-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Canis familiaris 30616 R-CFA-5671763 https://reactome.org/PathwayBrowser/#/R-CFA-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Canis familiaris 30616 R-CFA-5672008 https://reactome.org/PathwayBrowser/#/R-CFA-5672008 Thr-180 of ULK1 is phosphorylated IEA Canis familiaris 30616 R-CFA-5672010 https://reactome.org/PathwayBrowser/#/R-CFA-5672010 Active MTORC1 phosphorylates ULK1 IEA Canis familiaris 30616 R-CFA-5672012 https://reactome.org/PathwayBrowser/#/R-CFA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Canis familiaris 30616 R-CFA-5672027 https://reactome.org/PathwayBrowser/#/R-CFA-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Canis familiaris 30616 R-CFA-5672828 https://reactome.org/PathwayBrowser/#/R-CFA-5672828 mTORC1 phosphorylates AKT1S1 IEA Canis familiaris 30616 R-CFA-5672948 https://reactome.org/PathwayBrowser/#/R-CFA-5672948 MARK3 phosphorylates KSR1 IEA Canis familiaris 30616 R-CFA-5672969 https://reactome.org/PathwayBrowser/#/R-CFA-5672969 Phosphorylation of RAF IEA Canis familiaris 30616 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 30616 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 30616 R-CFA-5673768 https://reactome.org/PathwayBrowser/#/R-CFA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Canis familiaris 30616 R-CFA-5674130 https://reactome.org/PathwayBrowser/#/R-CFA-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Canis familiaris 30616 R-CFA-5674373 https://reactome.org/PathwayBrowser/#/R-CFA-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Canis familiaris 30616 R-CFA-5675194 https://reactome.org/PathwayBrowser/#/R-CFA-5675194 Activated MAPK phosphorylates RAF1 IEA Canis familiaris 30616 R-CFA-5675198 https://reactome.org/PathwayBrowser/#/R-CFA-5675198 Activated MAPKs phosphorylate BRAF IEA Canis familiaris 30616 R-CFA-5675868 https://reactome.org/PathwayBrowser/#/R-CFA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Canis familiaris 30616 R-CFA-5678706 https://reactome.org/PathwayBrowser/#/R-CFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Canis familiaris 30616 R-CFA-5678863 https://reactome.org/PathwayBrowser/#/R-CFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-5679041 https://reactome.org/PathwayBrowser/#/R-CFA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-5679205 https://reactome.org/PathwayBrowser/#/R-CFA-5679205 ULK1 phosphorylates Beclin-1 IEA Canis familiaris 30616 R-CFA-5682026 https://reactome.org/PathwayBrowser/#/R-CFA-5682026 MRN bound to shortened telomeres activates ATM IEA Canis familiaris 30616 R-CFA-5682101 https://reactome.org/PathwayBrowser/#/R-CFA-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Canis familiaris 30616 R-CFA-5682285 https://reactome.org/PathwayBrowser/#/R-CFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-5682598 https://reactome.org/PathwayBrowser/#/R-CFA-5682598 ATM phosphorylates HERC2 IEA Canis familiaris 30616 R-CFA-5682983 https://reactome.org/PathwayBrowser/#/R-CFA-5682983 ATM phosphorylates WHSC1 IEA Canis familiaris 30616 R-CFA-5683425 https://reactome.org/PathwayBrowser/#/R-CFA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Canis familiaris 30616 R-CFA-5683714 https://reactome.org/PathwayBrowser/#/R-CFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Canis familiaris 30616 R-CFA-5683792 https://reactome.org/PathwayBrowser/#/R-CFA-5683792 p-T68-CHEK2 autophosphorylates IEA Canis familiaris 30616 R-CFA-5683801 https://reactome.org/PathwayBrowser/#/R-CFA-5683801 CHEK2 phosphorylates BRCA1 IEA Canis familiaris 30616 R-CFA-5683964 https://reactome.org/PathwayBrowser/#/R-CFA-5683964 ATM phosphorylates EYA1-4 IEA Canis familiaris 30616 R-CFA-5684096 https://reactome.org/PathwayBrowser/#/R-CFA-5684096 CDK2 phosphorylates RBBP8 IEA Canis familiaris 30616 R-CFA-5684140 https://reactome.org/PathwayBrowser/#/R-CFA-5684140 ATM phosphorylates RBBP8 IEA Canis familiaris 30616 R-CFA-5684261 https://reactome.org/PathwayBrowser/#/R-CFA-5684261 MAP3K8 is phosphorylated IEA Canis familiaris 30616 R-CFA-5684267 https://reactome.org/PathwayBrowser/#/R-CFA-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex IEA Canis familiaris 30616 R-CFA-5684275 https://reactome.org/PathwayBrowser/#/R-CFA-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 IEA Canis familiaris 30616 R-CFA-5684806 https://reactome.org/PathwayBrowser/#/R-CFA-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN IEA Canis familiaris 30616 R-CFA-5684862 https://reactome.org/PathwayBrowser/#/R-CFA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Canis familiaris 30616 R-CFA-5684887 https://reactome.org/PathwayBrowser/#/R-CFA-5684887 Activation of CHEK1 at resected DNA DSBs IEA Canis familiaris 30616 R-CFA-5685156 https://reactome.org/PathwayBrowser/#/R-CFA-5685156 ATR phosphorylates RPA2 IEA Canis familiaris 30616 R-CFA-5685230 https://reactome.org/PathwayBrowser/#/R-CFA-5685230 CHEK1 phosphorylates RAD51 IEA Canis familiaris 30616 R-CFA-5686578 https://reactome.org/PathwayBrowser/#/R-CFA-5686578 Activated ATM phosphorylates ABL1 IEA Canis familiaris 30616 R-CFA-5686587 https://reactome.org/PathwayBrowser/#/R-CFA-5686587 ABL1 phosphorylates RAD52 IEA Canis familiaris 30616 R-CFA-5686704 https://reactome.org/PathwayBrowser/#/R-CFA-5686704 Activated ATM phosphorylates DCLRE1C IEA Canis familiaris 30616 R-CFA-5687086 https://reactome.org/PathwayBrowser/#/R-CFA-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Canis familiaris 30616 R-CFA-5687090 https://reactome.org/PathwayBrowser/#/R-CFA-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Canis familiaris 30616 R-CFA-5687183 https://reactome.org/PathwayBrowser/#/R-CFA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Canis familiaris 30616 R-CFA-5690702 https://reactome.org/PathwayBrowser/#/R-CFA-5690702 LYN phosphorylates CD22 IEA Canis familiaris 30616 R-CFA-5690996 https://reactome.org/PathwayBrowser/#/R-CFA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Canis familiaris 30616 R-CFA-5692462 https://reactome.org/PathwayBrowser/#/R-CFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Canis familiaris 30616 R-CFA-5692480 https://reactome.org/PathwayBrowser/#/R-CFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Canis familiaris 30616 R-CFA-5692755 https://reactome.org/PathwayBrowser/#/R-CFA-5692755 CDK1 phosphorylates MAPK6 IEA Canis familiaris 30616 R-CFA-5693148 https://reactome.org/PathwayBrowser/#/R-CFA-5693148 BCKDK phosphorylates BCKDH IEA Canis familiaris 30616 R-CFA-5693536 https://reactome.org/PathwayBrowser/#/R-CFA-5693536 ATM phosphorylates MDC1 IEA Canis familiaris 30616 R-CFA-5693540 https://reactome.org/PathwayBrowser/#/R-CFA-5693540 MRN activates ATM IEA Canis familiaris 30616 R-CFA-5693549 https://reactome.org/PathwayBrowser/#/R-CFA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Canis familiaris 30616 R-CFA-5693551 https://reactome.org/PathwayBrowser/#/R-CFA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Canis familiaris 30616 R-CFA-5693575 https://reactome.org/PathwayBrowser/#/R-CFA-5693575 DNA-PKcs autophosphorylates IEA Canis familiaris 30616 R-CFA-5693598 https://reactome.org/PathwayBrowser/#/R-CFA-5693598 ATM phosphorylates NBN IEA Canis familiaris 30616 R-CFA-5693609 https://reactome.org/PathwayBrowser/#/R-CFA-5693609 ATM phosphorylates TP53 at S15 IEA Canis familiaris 30616 R-CFA-5694425 https://reactome.org/PathwayBrowser/#/R-CFA-5694425 NSF ATPase activity dissociates cis-SNARE IEA Canis familiaris 30616 R-CFA-5694441 https://reactome.org/PathwayBrowser/#/R-CFA-5694441 CSNK1D phosphorylates SEC23 IEA Canis familiaris 30616 R-CFA-5695957 https://reactome.org/PathwayBrowser/#/R-CFA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Canis familiaris 30616 R-CFA-5696004 https://reactome.org/PathwayBrowser/#/R-CFA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Canis familiaris 30616 R-CFA-5696074 https://reactome.org/PathwayBrowser/#/R-CFA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Canis familiaris 30616 R-CFA-5696839 https://reactome.org/PathwayBrowser/#/R-CFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Canis familiaris 30616 R-CFA-6782131 https://reactome.org/PathwayBrowser/#/R-CFA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Canis familiaris 30616 R-CFA-6784006 https://reactome.org/PathwayBrowser/#/R-CFA-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Canis familiaris 30616 R-CFA-6784319 https://reactome.org/PathwayBrowser/#/R-CFA-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Canis familiaris 30616 R-CFA-6784324 https://reactome.org/PathwayBrowser/#/R-CFA-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Canis familiaris 30616 R-CFA-6786050 https://reactome.org/PathwayBrowser/#/R-CFA-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Canis familiaris 30616 R-CFA-6786095 https://reactome.org/PathwayBrowser/#/R-CFA-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Canis familiaris 30616 R-CFA-6786096 https://reactome.org/PathwayBrowser/#/R-CFA-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Canis familiaris 30616 R-CFA-6786245 https://reactome.org/PathwayBrowser/#/R-CFA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Canis familiaris 30616 R-CFA-6787540 https://reactome.org/PathwayBrowser/#/R-CFA-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Canis familiaris 30616 R-CFA-6788392 https://reactome.org/PathwayBrowser/#/R-CFA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Canis familiaris 30616 R-CFA-6788582 https://reactome.org/PathwayBrowser/#/R-CFA-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Canis familiaris 30616 R-CFA-6788798 https://reactome.org/PathwayBrowser/#/R-CFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 30616 R-CFA-6788810 https://reactome.org/PathwayBrowser/#/R-CFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 30616 R-CFA-6788855 https://reactome.org/PathwayBrowser/#/R-CFA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Canis familiaris 30616 R-CFA-6788867 https://reactome.org/PathwayBrowser/#/R-CFA-6788867 FN3K phosphorylates ketosamines IEA Canis familiaris 30616 R-CFA-6793661 https://reactome.org/PathwayBrowser/#/R-CFA-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Canis familiaris 30616 R-CFA-6795290 https://reactome.org/PathwayBrowser/#/R-CFA-6795290 TORC2 complex phosphorylates SGK1 IEA Canis familiaris 30616 R-CFA-6795460 https://reactome.org/PathwayBrowser/#/R-CFA-6795460 SGK1 phosphorylates MDM2 IEA Canis familiaris 30616 R-CFA-6795473 https://reactome.org/PathwayBrowser/#/R-CFA-6795473 PDPK1 phosphorylates SGK1 IEA Canis familiaris 30616 R-CFA-6797606 https://reactome.org/PathwayBrowser/#/R-CFA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Canis familiaris 30616 R-CFA-6798174 https://reactome.org/PathwayBrowser/#/R-CFA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Canis familiaris 30616 R-CFA-6798372 https://reactome.org/PathwayBrowser/#/R-CFA-6798372 ATM phosphorylates DYRK2 IEA Canis familiaris 30616 R-CFA-6798374 https://reactome.org/PathwayBrowser/#/R-CFA-6798374 DYRK2 phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6799097 https://reactome.org/PathwayBrowser/#/R-CFA-6799097 ATM phosphorylates ZNF420 IEA Canis familiaris 30616 R-CFA-6799246 https://reactome.org/PathwayBrowser/#/R-CFA-6799246 CHEK1 phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6799332 https://reactome.org/PathwayBrowser/#/R-CFA-6799332 ATR phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6799409 https://reactome.org/PathwayBrowser/#/R-CFA-6799409 HIPK2 phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6799495 https://reactome.org/PathwayBrowser/#/R-CFA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Canis familiaris 30616 R-CFA-6800490 https://reactome.org/PathwayBrowser/#/R-CFA-6800490 ATM phosphorylates PIDD1 IEA Canis familiaris 30616 R-CFA-6801342 https://reactome.org/PathwayBrowser/#/R-CFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Canis familiaris 30616 R-CFA-6801456 https://reactome.org/PathwayBrowser/#/R-CFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Canis familiaris 30616 R-CFA-6801666 https://reactome.org/PathwayBrowser/#/R-CFA-6801666 PLK2 phosphorylates CENPJ IEA Canis familiaris 30616 R-CFA-6801675 https://reactome.org/PathwayBrowser/#/R-CFA-6801675 PLK2 phosphorylates NPM1 IEA Canis familiaris 30616 R-CFA-6802973 https://reactome.org/PathwayBrowser/#/R-CFA-6802973 PLK3 phosphorylates CDC25C IEA Canis familiaris 30616 R-CFA-6803545 https://reactome.org/PathwayBrowser/#/R-CFA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Canis familiaris 30616 R-CFA-6803771 https://reactome.org/PathwayBrowser/#/R-CFA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Canis familiaris 30616 R-CFA-6804266 https://reactome.org/PathwayBrowser/#/R-CFA-6804266 CHEK2 phosphorylates TTC5 IEA Canis familiaris 30616 R-CFA-6804276 https://reactome.org/PathwayBrowser/#/R-CFA-6804276 ATM phosphorylates TTC5 IEA Canis familiaris 30616 R-CFA-6804596 https://reactome.org/PathwayBrowser/#/R-CFA-6804596 APAF1:CYCS binds APIP IEA Canis familiaris 30616 R-CFA-6804955 https://reactome.org/PathwayBrowser/#/R-CFA-6804955 ATM phosphorylates MDM2 IEA Canis familiaris 30616 R-CFA-6805059 https://reactome.org/PathwayBrowser/#/R-CFA-6805059 CK2:FACT phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6805103 https://reactome.org/PathwayBrowser/#/R-CFA-6805103 AURKA phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6805109 https://reactome.org/PathwayBrowser/#/R-CFA-6805109 CDK2 phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6805126 https://reactome.org/PathwayBrowser/#/R-CFA-6805126 AURKB phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6805276 https://reactome.org/PathwayBrowser/#/R-CFA-6805276 CDK5 phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6805285 https://reactome.org/PathwayBrowser/#/R-CFA-6805285 PLK3 phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6805399 https://reactome.org/PathwayBrowser/#/R-CFA-6805399 TAF1 phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6805470 https://reactome.org/PathwayBrowser/#/R-CFA-6805470 AMPK phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6805479 https://reactome.org/PathwayBrowser/#/R-CFA-6805479 TP53RK phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-6806877 https://reactome.org/PathwayBrowser/#/R-CFA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Canis familiaris 30616 R-CFA-6806967 https://reactome.org/PathwayBrowser/#/R-CFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Canis familiaris 30616 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 30616 R-CFA-6807868 https://reactome.org/PathwayBrowser/#/R-CFA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Canis familiaris 30616 R-CFA-6809015 https://reactome.org/PathwayBrowser/#/R-CFA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Canis familiaris 30616 R-CFA-6810233 https://reactome.org/PathwayBrowser/#/R-CFA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Canis familiaris 30616 R-CFA-6811422 https://reactome.org/PathwayBrowser/#/R-CFA-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Canis familiaris 30616 R-CFA-6811454 https://reactome.org/PathwayBrowser/#/R-CFA-6811454 MAPKs phosphorylate PP2A IEA Canis familiaris 30616 R-CFA-6811522 https://reactome.org/PathwayBrowser/#/R-CFA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Canis familiaris 30616 R-CFA-6814120 https://reactome.org/PathwayBrowser/#/R-CFA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Canis familiaris 30616 R-CFA-6814124 https://reactome.org/PathwayBrowser/#/R-CFA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Canis familiaris 30616 R-CFA-6814409 https://reactome.org/PathwayBrowser/#/R-CFA-6814409 CK2 phosphorylates PDCL IEA Canis familiaris 30616 R-CFA-6814549 https://reactome.org/PathwayBrowser/#/R-CFA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Canis familiaris 30616 R-CFA-6814559 https://reactome.org/PathwayBrowser/#/R-CFA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Canis familiaris 30616 R-CFA-6814670 https://reactome.org/PathwayBrowser/#/R-CFA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Canis familiaris 30616 R-CFA-6814675 https://reactome.org/PathwayBrowser/#/R-CFA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Canis familiaris 30616 R-CFA-6814678 https://reactome.org/PathwayBrowser/#/R-CFA-6814678 ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN IEA Canis familiaris 30616 R-CFA-68610 https://reactome.org/PathwayBrowser/#/R-CFA-68610 Formation of ORC(2-5) complex IEA Canis familiaris 30616 R-CFA-68944 https://reactome.org/PathwayBrowser/#/R-CFA-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Canis familiaris 30616 R-CFA-69005 https://reactome.org/PathwayBrowser/#/R-CFA-69005 Cdc6 protein is phosphorylated by CDK IEA Canis familiaris 30616 R-CFA-69015 https://reactome.org/PathwayBrowser/#/R-CFA-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Canis familiaris 30616 R-CFA-69063 https://reactome.org/PathwayBrowser/#/R-CFA-69063 Loading of PCNA - Sliding Clamp Formation IEA Canis familiaris 30616 R-CFA-69195 https://reactome.org/PathwayBrowser/#/R-CFA-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Canis familiaris 30616 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 30616 R-CFA-69604 https://reactome.org/PathwayBrowser/#/R-CFA-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Canis familiaris 30616 R-CFA-69608 https://reactome.org/PathwayBrowser/#/R-CFA-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Canis familiaris 30616 R-CFA-69685 https://reactome.org/PathwayBrowser/#/R-CFA-69685 CHEK2 phosphorylates TP53 IEA Canis familiaris 30616 R-CFA-69891 https://reactome.org/PathwayBrowser/#/R-CFA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Canis familiaris 30616 R-CFA-70349 https://reactome.org/PathwayBrowser/#/R-CFA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Canis familiaris 30616 R-CFA-70355 https://reactome.org/PathwayBrowser/#/R-CFA-70355 GALK1 phosphorylates Gal to Gal1P IEA Canis familiaris 30616 R-CFA-70420 https://reactome.org/PathwayBrowser/#/R-CFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Canis familiaris 30616 R-CFA-70467 https://reactome.org/PathwayBrowser/#/R-CFA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Canis familiaris 30616 R-CFA-70486 https://reactome.org/PathwayBrowser/#/R-CFA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Canis familiaris 30616 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 30616 R-CFA-70555 https://reactome.org/PathwayBrowser/#/R-CFA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Canis familiaris 30616 R-CFA-70577 https://reactome.org/PathwayBrowser/#/R-CFA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Canis familiaris 30616 R-CFA-70599 https://reactome.org/PathwayBrowser/#/R-CFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Canis familiaris 30616 R-CFA-70606 https://reactome.org/PathwayBrowser/#/R-CFA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Canis familiaris 30616 R-CFA-70773 https://reactome.org/PathwayBrowser/#/R-CFA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Canis familiaris 30616 R-CFA-70967 https://reactome.org/PathwayBrowser/#/R-CFA-70967 IDH3 complex decarboxylates isocitrate IEA Canis familiaris 30616 R-CFA-70997 https://reactome.org/PathwayBrowser/#/R-CFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Canis familiaris 30616 R-CFA-71031 https://reactome.org/PathwayBrowser/#/R-CFA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Canis familiaris 30616 R-CFA-71401 https://reactome.org/PathwayBrowser/#/R-CFA-71401 OGDH dimer decarboxylates 2-OG IEA Canis familiaris 30616 R-CFA-71541 https://reactome.org/PathwayBrowser/#/R-CFA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Canis familiaris 30616 R-CFA-71588 https://reactome.org/PathwayBrowser/#/R-CFA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Canis familiaris 30616 R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 30616 R-CFA-71735 https://reactome.org/PathwayBrowser/#/R-CFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Canis familiaris 30616 R-CFA-71802 https://reactome.org/PathwayBrowser/#/R-CFA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Canis familiaris 30616 R-CFA-71850 https://reactome.org/PathwayBrowser/#/R-CFA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Canis familiaris 30616 R-CFA-72180 https://reactome.org/PathwayBrowser/#/R-CFA-72180 Cleavage of mRNA at the 3'-end IEA Canis familiaris 30616 R-CFA-72621 https://reactome.org/PathwayBrowser/#/R-CFA-72621 Ribosomal scanning IEA Canis familiaris 30616 R-CFA-72647 https://reactome.org/PathwayBrowser/#/R-CFA-72647 Cap-bound mRNA is activated by helicases IEA Canis familiaris 30616 R-CFA-727819 https://reactome.org/PathwayBrowser/#/R-CFA-727819 TAK1 phosphorylates MKK6 IEA Canis familiaris 30616 R-CFA-73548 https://reactome.org/PathwayBrowser/#/R-CFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Canis familiaris 30616 R-CFA-73577 https://reactome.org/PathwayBrowser/#/R-CFA-73577 CAD hexamer transforms L-Gln to CAP IEA Canis familiaris 30616 R-CFA-73580 https://reactome.org/PathwayBrowser/#/R-CFA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Canis familiaris 30616 R-CFA-73598 https://reactome.org/PathwayBrowser/#/R-CFA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Canis familiaris 30616 R-CFA-73599 https://reactome.org/PathwayBrowser/#/R-CFA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Canis familiaris 30616 R-CFA-73632 https://reactome.org/PathwayBrowser/#/R-CFA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Canis familiaris 30616 R-CFA-73635 https://reactome.org/PathwayBrowser/#/R-CFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Canis familiaris 30616 R-CFA-73647 https://reactome.org/PathwayBrowser/#/R-CFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Canis familiaris 30616 R-CFA-73722 https://reactome.org/PathwayBrowser/#/R-CFA-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Canis familiaris 30616 R-CFA-73788 https://reactome.org/PathwayBrowser/#/R-CFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Canis familiaris 30616 R-CFA-73792 https://reactome.org/PathwayBrowser/#/R-CFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Canis familiaris 30616 R-CFA-73805 https://reactome.org/PathwayBrowser/#/R-CFA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Canis familiaris 30616 R-CFA-73810 https://reactome.org/PathwayBrowser/#/R-CFA-73810 FGAM + ATP => AIR + ADP + Pi IEA Canis familiaris 30616 R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 30616 R-CFA-73814 https://reactome.org/PathwayBrowser/#/R-CFA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Canis familiaris 30616 R-CFA-74207 https://reactome.org/PathwayBrowser/#/R-CFA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Canis familiaris 30616 R-CFA-74220 https://reactome.org/PathwayBrowser/#/R-CFA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Canis familiaris 30616 R-CFA-74711 https://reactome.org/PathwayBrowser/#/R-CFA-74711 Phosphorylation of IRS IEA Canis familiaris 30616 R-CFA-74715 https://reactome.org/PathwayBrowser/#/R-CFA-74715 Autophosphorylation of insulin receptor IEA Canis familiaris 30616 R-CFA-74742 https://reactome.org/PathwayBrowser/#/R-CFA-74742 Phosphorylation of SHC1 IEA Canis familiaris 30616 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 30616 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 30616 R-CFA-75010 https://reactome.org/PathwayBrowser/#/R-CFA-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Canis familiaris 30616 R-CFA-75125 https://reactome.org/PathwayBrowser/#/R-CFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Canis familiaris 30616 R-CFA-75126 https://reactome.org/PathwayBrowser/#/R-CFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Canis familiaris 30616 R-CFA-75809 https://reactome.org/PathwayBrowser/#/R-CFA-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Canis familiaris 30616 R-CFA-75848 https://reactome.org/PathwayBrowser/#/R-CFA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Canis familiaris 30616 R-CFA-75851 https://reactome.org/PathwayBrowser/#/R-CFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 30616 R-CFA-75887 https://reactome.org/PathwayBrowser/#/R-CFA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Canis familiaris 30616 R-CFA-75949 https://reactome.org/PathwayBrowser/#/R-CFA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Canis familiaris 30616 R-CFA-77071 https://reactome.org/PathwayBrowser/#/R-CFA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Canis familiaris 30616 R-CFA-844438 https://reactome.org/PathwayBrowser/#/R-CFA-844438 NLRP1 oligomerizes IEA Canis familiaris 30616 R-CFA-873918 https://reactome.org/PathwayBrowser/#/R-CFA-873918 Transphosphorylation of JAK1 IEA Canis familiaris 30616 R-CFA-873919 https://reactome.org/PathwayBrowser/#/R-CFA-873919 Phosphorylation of JAK2 IEA Canis familiaris 30616 R-CFA-873922 https://reactome.org/PathwayBrowser/#/R-CFA-873922 Phosphorylation of STAT1 by JAK kinases IEA Canis familiaris 30616 R-CFA-873924 https://reactome.org/PathwayBrowser/#/R-CFA-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Canis familiaris 30616 R-CFA-877187 https://reactome.org/PathwayBrowser/#/R-CFA-877187 P2X7 mediates loss of intracellular K+ IEA Canis familiaris 30616 R-CFA-877198 https://reactome.org/PathwayBrowser/#/R-CFA-877198 P2X7 mediates membrane pores that include pannexin-1 IEA Canis familiaris 30616 R-CFA-879222 https://reactome.org/PathwayBrowser/#/R-CFA-879222 MDP:NLRP1 binds ATP IEA Canis familiaris 30616 R-CFA-879907 https://reactome.org/PathwayBrowser/#/R-CFA-879907 Tyrosine kinases phosphorylate the receptor IEA Canis familiaris 30616 R-CFA-879909 https://reactome.org/PathwayBrowser/#/R-CFA-879909 Activation of STAT5a/b by JAK2 IEA Canis familiaris 30616 R-CFA-879910 https://reactome.org/PathwayBrowser/#/R-CFA-879910 JAK2 is phosphorylated, activated IEA Canis familiaris 30616 R-CFA-8847638 https://reactome.org/PathwayBrowser/#/R-CFA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Canis familiaris 30616 R-CFA-8847977 https://reactome.org/PathwayBrowser/#/R-CFA-8847977 FRK phosphorylates PTEN IEA Canis familiaris 30616 R-CFA-8848053 https://reactome.org/PathwayBrowser/#/R-CFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Canis familiaris 30616 R-CFA-8849157 https://reactome.org/PathwayBrowser/#/R-CFA-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Canis familiaris 30616 R-CFA-8850945 https://reactome.org/PathwayBrowser/#/R-CFA-8850945 Casein kinase II phosphorylates PTEN IEA Canis familiaris 30616 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 30616 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 30616 R-CFA-8851797 https://reactome.org/PathwayBrowser/#/R-CFA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Canis familiaris 30616 R-CFA-8851890 https://reactome.org/PathwayBrowser/#/R-CFA-8851890 MET phosphorylates SHC1-2 IEA Canis familiaris 30616 R-CFA-8851933 https://reactome.org/PathwayBrowser/#/R-CFA-8851933 MET phosphorylates GAB1 IEA Canis familiaris 30616 R-CFA-8852019 https://reactome.org/PathwayBrowser/#/R-CFA-8852019 MET bound PI3K generates PIP3 IEA Canis familiaris 30616 R-CFA-8852128 https://reactome.org/PathwayBrowser/#/R-CFA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Canis familiaris 30616 R-CFA-8852131 https://reactome.org/PathwayBrowser/#/R-CFA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Canis familiaris 30616 R-CFA-8852132 https://reactome.org/PathwayBrowser/#/R-CFA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Canis familiaris 30616 R-CFA-8852134 https://reactome.org/PathwayBrowser/#/R-CFA-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Canis familiaris 30616 R-CFA-8852306 https://reactome.org/PathwayBrowser/#/R-CFA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Canis familiaris 30616 R-CFA-8852317 https://reactome.org/PathwayBrowser/#/R-CFA-8852317 PLK1 phosphorylates GTSE1 IEA Canis familiaris 30616 R-CFA-8852552 https://reactome.org/PathwayBrowser/#/R-CFA-8852552 MST1R autophosphorylates IEA Canis familiaris 30616 R-CFA-8853419 https://reactome.org/PathwayBrowser/#/R-CFA-8853419 TPX2 promotes AURKA autophosphorylation IEA Canis familiaris 30616 R-CFA-8853444 https://reactome.org/PathwayBrowser/#/R-CFA-8853444 AURKA phosphorylates PHLDA1 IEA Canis familiaris 30616 R-CFA-8853774 https://reactome.org/PathwayBrowser/#/R-CFA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Canis familiaris 30616 R-CFA-8853792 https://reactome.org/PathwayBrowser/#/R-CFA-8853792 RET tyrosine phosphorylation IEA Canis familiaris 30616 R-CFA-8854908 https://reactome.org/PathwayBrowser/#/R-CFA-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Canis familiaris 30616 R-CFA-8855237 https://reactome.org/PathwayBrowser/#/R-CFA-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Canis familiaris 30616 R-CFA-8856813 https://reactome.org/PathwayBrowser/#/R-CFA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Canis familiaris 30616 R-CFA-8857925 https://reactome.org/PathwayBrowser/#/R-CFA-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Canis familiaris 30616 R-CFA-8865774 https://reactome.org/PathwayBrowser/#/R-CFA-8865774 TTLLs polyglutamylate tubulin IEA Canis familiaris 30616 R-CFA-8866268 https://reactome.org/PathwayBrowser/#/R-CFA-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Canis familiaris 30616 R-CFA-8866405 https://reactome.org/PathwayBrowser/#/R-CFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 30616 R-CFA-8866542 https://reactome.org/PathwayBrowser/#/R-CFA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Canis familiaris 30616 R-CFA-8867041 https://reactome.org/PathwayBrowser/#/R-CFA-8867041 EGFR phosphorylates EPS15 IEA Canis familiaris 30616 R-CFA-8867370 https://reactome.org/PathwayBrowser/#/R-CFA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Canis familiaris 30616 R-CFA-8868066 https://reactome.org/PathwayBrowser/#/R-CFA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Canis familiaris 30616 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 30616 R-CFA-8868118 https://reactome.org/PathwayBrowser/#/R-CFA-8868118 MAPK12 phosphorylates PTPN3 IEA Canis familiaris 30616 R-CFA-8868230 https://reactome.org/PathwayBrowser/#/R-CFA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Canis familiaris 30616 R-CFA-8868236 https://reactome.org/PathwayBrowser/#/R-CFA-8868236 BAR domain proteins recruit dynamin IEA Canis familiaris 30616 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 30616 R-CFA-8868651 https://reactome.org/PathwayBrowser/#/R-CFA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Canis familiaris 30616 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 30616 R-CFA-8868659 https://reactome.org/PathwayBrowser/#/R-CFA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Canis familiaris 30616 R-CFA-8868660 https://reactome.org/PathwayBrowser/#/R-CFA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Canis familiaris 30616 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 30616 R-CFA-8869606 https://reactome.org/PathwayBrowser/#/R-CFA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Canis familiaris 30616 R-CFA-8869633 https://reactome.org/PathwayBrowser/#/R-CFA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Canis familiaris 30616 R-CFA-8871193 https://reactome.org/PathwayBrowser/#/R-CFA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Canis familiaris 30616 R-CFA-8871194 https://reactome.org/PathwayBrowser/#/R-CFA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Canis familiaris 30616 R-CFA-8871373 https://reactome.org/PathwayBrowser/#/R-CFA-8871373 BMX phosphorylates RUFY1 IEA Canis familiaris 30616 R-CFA-8873929 https://reactome.org/PathwayBrowser/#/R-CFA-8873929 Casein kinase II phosphorylates STARD10 IEA Canis familiaris 30616 R-CFA-8874078 https://reactome.org/PathwayBrowser/#/R-CFA-8874078 PTK2 autophosphorylates IEA Canis familiaris 30616 R-CFA-8874080 https://reactome.org/PathwayBrowser/#/R-CFA-8874080 SRC phosphorylates PTK2 IEA Canis familiaris 30616 R-CFA-8874082 https://reactome.org/PathwayBrowser/#/R-CFA-8874082 MET phosphorylates PTK2 IEA Canis familiaris 30616 R-CFA-8875071 https://reactome.org/PathwayBrowser/#/R-CFA-8875071 ACSS3 ligates CoA to CH3COO- IEA Canis familiaris 30616 R-CFA-8875451 https://reactome.org/PathwayBrowser/#/R-CFA-8875451 MET phosphorylates CBL IEA Canis familiaris 30616 R-CFA-8875817 https://reactome.org/PathwayBrowser/#/R-CFA-8875817 MET phosphorylates STAT3 IEA Canis familiaris 30616 R-CFA-8876446 https://reactome.org/PathwayBrowser/#/R-CFA-8876446 p-ULK1 phosphorylates DENND3 IEA Canis familiaris 30616 R-CFA-8876889 https://reactome.org/PathwayBrowser/#/R-CFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 30616 R-CFA-8877691 https://reactome.org/PathwayBrowser/#/R-CFA-8877691 MAP2K6 phosphorylates PIP4K2B IEA Canis familiaris 30616 R-CFA-8878050 https://reactome.org/PathwayBrowser/#/R-CFA-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Canis familiaris 30616 R-CFA-8878054 https://reactome.org/PathwayBrowser/#/R-CFA-8878054 HIPK2 phosphorylates RUNX1 IEA Canis familiaris 30616 R-CFA-8931653 https://reactome.org/PathwayBrowser/#/R-CFA-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Canis familiaris 30616 R-CFA-8934446 https://reactome.org/PathwayBrowser/#/R-CFA-8934446 Activated PKC phosphorylates SHC1 IEA Canis familiaris 30616 R-CFA-8937807 https://reactome.org/PathwayBrowser/#/R-CFA-8937807 SRC phosphorylates RUNX3 IEA Canis familiaris 30616 R-CFA-8939959 https://reactome.org/PathwayBrowser/#/R-CFA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Canis familiaris 30616 R-CFA-8940100 https://reactome.org/PathwayBrowser/#/R-CFA-8940100 CDK1 phosphorylates VCPIP1 IEA Canis familiaris 30616 R-CFA-8942575 https://reactome.org/PathwayBrowser/#/R-CFA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Canis familiaris 30616 R-CFA-8942607 https://reactome.org/PathwayBrowser/#/R-CFA-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Canis familiaris 30616 R-CFA-8942836 https://reactome.org/PathwayBrowser/#/R-CFA-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Canis familiaris 30616 R-CFA-8944454 https://reactome.org/PathwayBrowser/#/R-CFA-8944454 mTORC1 phosphorylates MAF1 IEA Canis familiaris 30616 R-CFA-8948039 https://reactome.org/PathwayBrowser/#/R-CFA-8948039 FUNDC1 is phosphorylated by CK2 IEA Canis familiaris 30616 R-CFA-8948143 https://reactome.org/PathwayBrowser/#/R-CFA-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Canis familiaris 30616 R-CFA-8948146 https://reactome.org/PathwayBrowser/#/R-CFA-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Canis familiaris 30616 R-CFA-8950269 https://reactome.org/PathwayBrowser/#/R-CFA-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Canis familiaris 30616 R-CFA-8950340 https://reactome.org/PathwayBrowser/#/R-CFA-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Canis familiaris 30616 R-CFA-8950405 https://reactome.org/PathwayBrowser/#/R-CFA-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Canis familiaris 30616 R-CFA-8950423 https://reactome.org/PathwayBrowser/#/R-CFA-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Canis familiaris 30616 R-CFA-8950453 https://reactome.org/PathwayBrowser/#/R-CFA-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Canis familiaris 30616 R-CFA-8950485 https://reactome.org/PathwayBrowser/#/R-CFA-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Canis familiaris 30616 R-CFA-8950537 https://reactome.org/PathwayBrowser/#/R-CFA-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Canis familiaris 30616 R-CFA-8950757 https://reactome.org/PathwayBrowser/#/R-CFA-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Canis familiaris 30616 R-CFA-8951648 https://reactome.org/PathwayBrowser/#/R-CFA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Canis familiaris 30616 R-CFA-8951656 https://reactome.org/PathwayBrowser/#/R-CFA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Canis familiaris 30616 R-CFA-8952289 https://reactome.org/PathwayBrowser/#/R-CFA-8952289 FAM20C phosphorylates FAM20C substrates IEA Canis familiaris 30616 R-CFA-8954327 https://reactome.org/PathwayBrowser/#/R-CFA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Canis familiaris 30616 R-CFA-8955030 https://reactome.org/PathwayBrowser/#/R-CFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Canis familiaris 30616 R-CFA-8955844 https://reactome.org/PathwayBrowser/#/R-CFA-8955844 RBKS phosphorylates ribose to R5P IEA Canis familiaris 30616 R-CFA-8956659 https://reactome.org/PathwayBrowser/#/R-CFA-8956659 ABL1 phosphorylates YAP1 IEA Canis familiaris 30616 R-CFA-8959510 https://reactome.org/PathwayBrowser/#/R-CFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Canis familiaris 30616 R-CFA-8959719 https://reactome.org/PathwayBrowser/#/R-CFA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Canis familiaris 30616 R-CFA-8964242 https://reactome.org/PathwayBrowser/#/R-CFA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Canis familiaris 30616 R-CFA-8982163 https://reactome.org/PathwayBrowser/#/R-CFA-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Canis familiaris 30616 R-CFA-8983059 https://reactome.org/PathwayBrowser/#/R-CFA-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Canis familiaris 30616 R-CFA-8983063 https://reactome.org/PathwayBrowser/#/R-CFA-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Canis familiaris 30616 R-CFA-8983300 https://reactome.org/PathwayBrowser/#/R-CFA-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Canis familiaris 30616 R-CFA-8983371 https://reactome.org/PathwayBrowser/#/R-CFA-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Canis familiaris 30616 R-CFA-8983834 https://reactome.org/PathwayBrowser/#/R-CFA-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Canis familiaris 30616 R-CFA-8983835 https://reactome.org/PathwayBrowser/#/R-CFA-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Canis familiaris 30616 R-CFA-8983870 https://reactome.org/PathwayBrowser/#/R-CFA-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Canis familiaris 30616 R-CFA-8983872 https://reactome.org/PathwayBrowser/#/R-CFA-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Canis familiaris 30616 R-CFA-8984012 https://reactome.org/PathwayBrowser/#/R-CFA-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Canis familiaris 30616 R-CFA-8984014 https://reactome.org/PathwayBrowser/#/R-CFA-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Canis familiaris 30616 R-CFA-8985914 https://reactome.org/PathwayBrowser/#/R-CFA-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Canis familiaris 30616 R-CFA-8985973 https://reactome.org/PathwayBrowser/#/R-CFA-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Canis familiaris 30616 R-CFA-8985988 https://reactome.org/PathwayBrowser/#/R-CFA-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Canis familiaris 30616 R-CFA-8986985 https://reactome.org/PathwayBrowser/#/R-CFA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Canis familiaris 30616 R-CFA-8986994 https://reactome.org/PathwayBrowser/#/R-CFA-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Canis familiaris 30616 R-CFA-8986995 https://reactome.org/PathwayBrowser/#/R-CFA-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Canis familiaris 30616 R-CFA-8987012 https://reactome.org/PathwayBrowser/#/R-CFA-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Canis familiaris 30616 R-CFA-8987040 https://reactome.org/PathwayBrowser/#/R-CFA-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Canis familiaris 30616 R-CFA-8987042 https://reactome.org/PathwayBrowser/#/R-CFA-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Canis familiaris 30616 R-CFA-8987070 https://reactome.org/PathwayBrowser/#/R-CFA-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Canis familiaris 30616 R-CFA-8987084 https://reactome.org/PathwayBrowser/#/R-CFA-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Canis familiaris 30616 R-CFA-8987096 https://reactome.org/PathwayBrowser/#/R-CFA-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Canis familiaris 30616 R-CFA-8987129 https://reactome.org/PathwayBrowser/#/R-CFA-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Canis familiaris 30616 R-CFA-8987141 https://reactome.org/PathwayBrowser/#/R-CFA-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Canis familiaris 30616 R-CFA-8987150 https://reactome.org/PathwayBrowser/#/R-CFA-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Canis familiaris 30616 R-CFA-8987179 https://reactome.org/PathwayBrowser/#/R-CFA-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Canis familiaris 30616 R-CFA-8987202 https://reactome.org/PathwayBrowser/#/R-CFA-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Canis familiaris 30616 R-CFA-8987255 https://reactome.org/PathwayBrowser/#/R-CFA-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Canis familiaris 30616 R-CFA-9006850 https://reactome.org/PathwayBrowser/#/R-CFA-9006850 IL21 receptor JAK phosphorylation IEA Canis familiaris 30616 R-CFA-9006870 https://reactome.org/PathwayBrowser/#/R-CFA-9006870 IL21 receptor STAT phosphorylation IEA Canis familiaris 30616 R-CFA-9007539 https://reactome.org/PathwayBrowser/#/R-CFA-9007539 CHEK1 phosphorylates E2F6 IEA Canis familiaris 30616 R-CFA-9008043 https://reactome.org/PathwayBrowser/#/R-CFA-9008043 MAPK8 phosphorylation IEA Canis familiaris 30616 R-CFA-9008412 https://reactome.org/PathwayBrowser/#/R-CFA-9008412 CDK4 phosphorylates RUNX2 IEA Canis familiaris 30616 R-CFA-9008684 https://reactome.org/PathwayBrowser/#/R-CFA-9008684 TBK1 phosphorylation IEA Canis familiaris 30616 R-CFA-9009072 https://reactome.org/PathwayBrowser/#/R-CFA-9009072 STAT3 phosphorylation IEA Canis familiaris 30616 R-CFA-9009282 https://reactome.org/PathwayBrowser/#/R-CFA-9009282 CDK1 phosphorylates RUNX2 IEA Canis familiaris 30616 R-CFA-9009936 https://reactome.org/PathwayBrowser/#/R-CFA-9009936 RNASEL cleaves cellular ssRNA IEA Canis familiaris 30616 R-CFA-9009950 https://reactome.org/PathwayBrowser/#/R-CFA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Canis familiaris 30616 R-CFA-9010681 https://reactome.org/PathwayBrowser/#/R-CFA-9010681 PKC phosphorylates ROBO3.1 IEA Canis familiaris 30616 R-CFA-9012268 https://reactome.org/PathwayBrowser/#/R-CFA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Canis familiaris 30616 R-CFA-9012319 https://reactome.org/PathwayBrowser/#/R-CFA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Canis familiaris 30616 R-CFA-9014741 https://reactome.org/PathwayBrowser/#/R-CFA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Canis familiaris 30616 R-CFA-9014766 https://reactome.org/PathwayBrowser/#/R-CFA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Canis familiaris 30616 R-CFA-9021357 https://reactome.org/PathwayBrowser/#/R-CFA-9021357 PRKCI phosphorylates ELF3 IEA Canis familiaris 30616 R-CFA-9021609 https://reactome.org/PathwayBrowser/#/R-CFA-9021609 ESR-associated SRC autophosphorylates IEA Canis familiaris 30616 R-CFA-9021627 https://reactome.org/PathwayBrowser/#/R-CFA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 30616 R-CFA-9022314 https://reactome.org/PathwayBrowser/#/R-CFA-9022314 HIPK2 phosphorylates MECP2 IEA Canis familiaris 30616 R-CFA-9027272 https://reactome.org/PathwayBrowser/#/R-CFA-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Canis familiaris 30616 R-CFA-9027273 https://reactome.org/PathwayBrowser/#/R-CFA-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Canis familiaris 30616 R-CFA-9034714 https://reactome.org/PathwayBrowser/#/R-CFA-9034714 NTRK3 dimers trans-autophosphorylate IEA Canis familiaris 30616 R-CFA-909552 https://reactome.org/PathwayBrowser/#/R-CFA-909552 Phosphorylation of STAT1 at Ser727 IEA Canis familiaris 30616 R-CFA-909718 https://reactome.org/PathwayBrowser/#/R-CFA-909718 Formation of p-STAT1 homodimer IEA Canis familiaris 30616 R-CFA-909729 https://reactome.org/PathwayBrowser/#/R-CFA-909729 Activation of JAK kinases IEA Canis familiaris 30616 R-CFA-909730 https://reactome.org/PathwayBrowser/#/R-CFA-909730 Phosphorylation of INFAR1 by TYK2 IEA Canis familiaris 30616 R-CFA-909732 https://reactome.org/PathwayBrowser/#/R-CFA-909732 Phosphorylation of STAT2 IEA Canis familiaris 30616 R-CFA-912527 https://reactome.org/PathwayBrowser/#/R-CFA-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Canis familiaris 30616 R-CFA-913996 https://reactome.org/PathwayBrowser/#/R-CFA-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Canis familiaris 30616 R-CFA-917841 https://reactome.org/PathwayBrowser/#/R-CFA-917841 Acidification of Tf:TfR1 containing endosome IEA Canis familiaris 30616 R-CFA-917979 https://reactome.org/PathwayBrowser/#/R-CFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-927889 https://reactome.org/PathwayBrowser/#/R-CFA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Canis familiaris 30616 R-CFA-934559 https://reactome.org/PathwayBrowser/#/R-CFA-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Canis familiaris 30616 R-CFA-936802 https://reactome.org/PathwayBrowser/#/R-CFA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Canis familiaris 30616 R-CFA-936883 https://reactome.org/PathwayBrowser/#/R-CFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Canis familiaris 30616 R-CFA-936895 https://reactome.org/PathwayBrowser/#/R-CFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Canis familiaris 30616 R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 30616 R-CFA-936951 https://reactome.org/PathwayBrowser/#/R-CFA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Canis familiaris 30616 R-CFA-936991 https://reactome.org/PathwayBrowser/#/R-CFA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Canis familiaris 30616 R-CFA-937034 https://reactome.org/PathwayBrowser/#/R-CFA-937034 IRAK1 phosphorylates Pellino IEA Canis familiaris 30616 R-CFA-937311 https://reactome.org/PathwayBrowser/#/R-CFA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Canis familiaris 30616 R-CFA-939763 https://reactome.org/PathwayBrowser/#/R-CFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Canis familiaris 30616 R-CFA-947531 https://reactome.org/PathwayBrowser/#/R-CFA-947531 Molybdenum ion transfer onto molybdopterin IEA Canis familiaris 30616 R-CFA-947591 https://reactome.org/PathwayBrowser/#/R-CFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Canis familiaris 30616 R-CFA-9603420 https://reactome.org/PathwayBrowser/#/R-CFA-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Canis familiaris 30616 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 30616 R-CFA-9606884 https://reactome.org/PathwayBrowser/#/R-CFA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Canis familiaris 30616 R-CFA-9612501 https://reactome.org/PathwayBrowser/#/R-CFA-9612501 SGK phosphorylates CREB1 IEA Canis familiaris 30616 R-CFA-9612509 https://reactome.org/PathwayBrowser/#/R-CFA-9612509 SGK phosphorylates SRF IEA Canis familiaris 30616 R-CFA-9613494 https://reactome.org/PathwayBrowser/#/R-CFA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Canis familiaris 30616 R-CFA-9619355 https://reactome.org/PathwayBrowser/#/R-CFA-9619355 CaMKK autophosphorylates in the cytosol IEA Canis familiaris 30616 R-CFA-9624800 https://reactome.org/PathwayBrowser/#/R-CFA-9624800 CDK1 phosphorylates LBR IEA Canis familiaris 30616 R-CFA-9625487 https://reactome.org/PathwayBrowser/#/R-CFA-9625487 PTK2 autophosphorylates downstream of EGFR IEA Canis familiaris 30616 R-CFA-9626817 https://reactome.org/PathwayBrowser/#/R-CFA-9626817 PKC phosphorylates NCF1 IEA Canis familiaris 30616 R-CFA-9626832 https://reactome.org/PathwayBrowser/#/R-CFA-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Canis familiaris 30616 R-CFA-9626880 https://reactome.org/PathwayBrowser/#/R-CFA-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Canis familiaris 30616 R-CFA-9627056 https://reactome.org/PathwayBrowser/#/R-CFA-9627056 Procaspase 9 forms dimer IEA Canis familiaris 30616 R-CFA-9627089 https://reactome.org/PathwayBrowser/#/R-CFA-9627089 CASP9 is phosphorylated at T412 IEA Canis familiaris 30616 R-CFA-9632858 https://reactome.org/PathwayBrowser/#/R-CFA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Canis familiaris 30616 R-CFA-9632868 https://reactome.org/PathwayBrowser/#/R-CFA-9632868 CDKN1B is phosphorylated in response to estrogen IEA Canis familiaris 30616 R-CFA-9645442 https://reactome.org/PathwayBrowser/#/R-CFA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Canis familiaris 30616 R-CFA-9645535 https://reactome.org/PathwayBrowser/#/R-CFA-9645535 ALPK1 phosphorylates TIFA IEA Canis familiaris 30616 R-CFA-9648089 https://reactome.org/PathwayBrowser/#/R-CFA-9648089 NEK6 and NEK7 phosphorylate EML4 IEA Canis familiaris 30616 R-CFA-964958 https://reactome.org/PathwayBrowser/#/R-CFA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Canis familiaris 30616 R-CFA-964962 https://reactome.org/PathwayBrowser/#/R-CFA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Canis familiaris 30616 R-CFA-964970 https://reactome.org/PathwayBrowser/#/R-CFA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Canis familiaris 30616 R-CFA-9653503 https://reactome.org/PathwayBrowser/#/R-CFA-9653503 KRAS4B is phosphorylated on serine 181 IEA Canis familiaris 30616 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 30616 R-CFA-9661417 https://reactome.org/PathwayBrowser/#/R-CFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-9668419 https://reactome.org/PathwayBrowser/#/R-CFA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Canis familiaris 30616 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 30616 R-CFA-9684118 https://reactome.org/PathwayBrowser/#/R-CFA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Canis familiaris 30616 R-CFA-9686521 https://reactome.org/PathwayBrowser/#/R-CFA-9686521 CDK2:CCNA phosphorylates TERF2 IEA Canis familiaris 30616 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 30616 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 30616 R-CFA-9699578 https://reactome.org/PathwayBrowser/#/R-CFA-9699578 Active FLT3 phosphorylates CDKN1B IEA Canis familiaris 30616 R-CFA-9700168 https://reactome.org/PathwayBrowser/#/R-CFA-9700168 Active ALK phosphorylates IRS1 IEA Canis familiaris 30616 R-CFA-9700171 https://reactome.org/PathwayBrowser/#/R-CFA-9700171 Active ALK phosphorylates PLCG1 IEA Canis familiaris 30616 R-CFA-9700175 https://reactome.org/PathwayBrowser/#/R-CFA-9700175 Active ALK phosphorylates SHC1 IEA Canis familiaris 30616 R-CFA-9701488 https://reactome.org/PathwayBrowser/#/R-CFA-9701488 Active ALK phosphorylates JAK3 IEA Canis familiaris 30616 R-CFA-9705925 https://reactome.org/PathwayBrowser/#/R-CFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Canis familiaris 30616 R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 30616 R-CFA-9706344 https://reactome.org/PathwayBrowser/#/R-CFA-9706344 FLT3 phosphorylates GRB10 IEA Canis familiaris 30616 R-CFA-9706350 https://reactome.org/PathwayBrowser/#/R-CFA-9706350 FLT3 phosphorylates CBL IEA Canis familiaris 30616 R-CFA-9706390 https://reactome.org/PathwayBrowser/#/R-CFA-9706390 RHOBTB3 binds interacting proteins at trans-Golgi network IEA Canis familiaris 30616 R-CFA-9706393 https://reactome.org/PathwayBrowser/#/R-CFA-9706393 RHOBTB3 binds ATP IEA Canis familiaris 30616 R-CFA-9706399 https://reactome.org/PathwayBrowser/#/R-CFA-9706399 RHOBTB3 hydrolyzes ATP IEA Canis familiaris 30616 R-CFA-9706837 https://reactome.org/PathwayBrowser/#/R-CFA-9706837 AR binds AR antagonists IEA Canis familiaris 30616 R-CFA-9725855 https://reactome.org/PathwayBrowser/#/R-CFA-9725855 NR3C2 binds NR3C2 antagonists IEA Canis familiaris 30616 R-CFA-9725885 https://reactome.org/PathwayBrowser/#/R-CFA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Canis familiaris 30616 R-CFA-9726509 https://reactome.org/PathwayBrowser/#/R-CFA-9726509 NR3C2 binds fludrocortisone IEA Canis familiaris 30616 R-CFA-9726580 https://reactome.org/PathwayBrowser/#/R-CFA-9726580 PGR binds PGR agonists IEA Canis familiaris 30616 R-CFA-9726621 https://reactome.org/PathwayBrowser/#/R-CFA-9726621 PGR binds PGR antagonists IEA Canis familiaris 30616 R-CFA-9727198 https://reactome.org/PathwayBrowser/#/R-CFA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Canis familiaris 30616 R-CFA-9731111 https://reactome.org/PathwayBrowser/#/R-CFA-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Canis familiaris 30616 R-CFA-9732738 https://reactome.org/PathwayBrowser/#/R-CFA-9732738 JAK1-mediated phosphorylation of RAF1 IEA Canis familiaris 30616 R-CFA-9732753 https://reactome.org/PathwayBrowser/#/R-CFA-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Canis familiaris 30616 R-CFA-9734535 https://reactome.org/PathwayBrowser/#/R-CFA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Canis familiaris 30616 R-CFA-9734547 https://reactome.org/PathwayBrowser/#/R-CFA-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Canis familiaris 30616 R-CFA-9734687 https://reactome.org/PathwayBrowser/#/R-CFA-9734687 ORC6 is phosphorylated on T195 IEA Canis familiaris 30616 R-CFA-9748949 https://reactome.org/PathwayBrowser/#/R-CFA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Canis familiaris 30616 R-CFA-9748957 https://reactome.org/PathwayBrowser/#/R-CFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Canis familiaris 30616 R-CFA-9748963 https://reactome.org/PathwayBrowser/#/R-CFA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Canis familiaris 30616 R-CFA-9748969 https://reactome.org/PathwayBrowser/#/R-CFA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Canis familiaris 30616 R-CFA-9748999 https://reactome.org/PathwayBrowser/#/R-CFA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Canis familiaris 30616 R-CFA-9749971 https://reactome.org/PathwayBrowser/#/R-CFA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Canis familiaris 30616 R-CFA-9750546 https://reactome.org/PathwayBrowser/#/R-CFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-9750617 https://reactome.org/PathwayBrowser/#/R-CFA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-9750656 https://reactome.org/PathwayBrowser/#/R-CFA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Canis familiaris 30616 R-CFA-975103 https://reactome.org/PathwayBrowser/#/R-CFA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Canis familiaris 30616 R-CFA-975139 https://reactome.org/PathwayBrowser/#/R-CFA-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Canis familiaris 30616 R-CFA-9753278 https://reactome.org/PathwayBrowser/#/R-CFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 30616 R-CFA-9753283 https://reactome.org/PathwayBrowser/#/R-CFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 30616 R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 30616 R-CFA-9754974 https://reactome.org/PathwayBrowser/#/R-CFA-9754974 ADK phosphorylates RBV IEA Canis familiaris 30616 R-CFA-9755013 https://reactome.org/PathwayBrowser/#/R-CFA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Canis familiaris 30616 R-CFA-9759206 https://reactome.org/PathwayBrowser/#/R-CFA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Canis familiaris 30616 R-CFA-9759454 https://reactome.org/PathwayBrowser/#/R-CFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Canis familiaris 30616 R-CFA-9759461 https://reactome.org/PathwayBrowser/#/R-CFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Canis familiaris 30616 R-CFA-9760094 https://reactome.org/PathwayBrowser/#/R-CFA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Canis familiaris 30616 R-CFA-9762094 https://reactome.org/PathwayBrowser/#/R-CFA-9762094 GSK3B phosphorylates p-NFE2L2 IEA Canis familiaris 30616 R-CFA-9770141 https://reactome.org/PathwayBrowser/#/R-CFA-9770141 Formation of the Spliceosomal C* complex IEA Canis familiaris 30616 R-CFA-9770142 https://reactome.org/PathwayBrowser/#/R-CFA-9770142 Formation of the Spliceosomal B complex IEA Canis familiaris 30616 R-CFA-9773803 https://reactome.org/PathwayBrowser/#/R-CFA-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Canis familiaris 30616 R-CFA-9794120 https://reactome.org/PathwayBrowser/#/R-CFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Canis familiaris 30616 R-CFA-9794572 https://reactome.org/PathwayBrowser/#/R-CFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Canis familiaris 30616 R-CFA-9796053 https://reactome.org/PathwayBrowser/#/R-CFA-9796053 PRKCI phosphorylates NFE2L2 IEA Canis familiaris 30616 R-CFA-9796067 https://reactome.org/PathwayBrowser/#/R-CFA-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Canis familiaris 30616 R-CFA-9817397 https://reactome.org/PathwayBrowser/#/R-CFA-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Canis familiaris 30616 R-CFA-9818789 https://reactome.org/PathwayBrowser/#/R-CFA-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Canis familiaris 30616 R-CFA-9819106 https://reactome.org/PathwayBrowser/#/R-CFA-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Canis familiaris 30616 R-CFA-9823906 https://reactome.org/PathwayBrowser/#/R-CFA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Canis familiaris 30616 R-CFA-9824882 https://reactome.org/PathwayBrowser/#/R-CFA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Canis familiaris 30616 R-CFA-9824977 https://reactome.org/PathwayBrowser/#/R-CFA-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Canis familiaris 30616 R-CFA-9824994 https://reactome.org/PathwayBrowser/#/R-CFA-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Canis familiaris 30616 R-CFA-9824995 https://reactome.org/PathwayBrowser/#/R-CFA-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Canis familiaris 30616 R-CFA-9824999 https://reactome.org/PathwayBrowser/#/R-CFA-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Canis familiaris 30616 R-CFA-9825759 https://reactome.org/PathwayBrowser/#/R-CFA-9825759 MAPK-dependent phosphorylation of KARS IEA Canis familiaris 30616 R-CFA-982810 https://reactome.org/PathwayBrowser/#/R-CFA-982810 JAK2 phosphorylation IEA Canis familiaris 30616 R-CFA-983140 https://reactome.org/PathwayBrowser/#/R-CFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Canis familiaris 30616 R-CFA-983153 https://reactome.org/PathwayBrowser/#/R-CFA-983153 E1 mediated ubiquitin activation IEA Canis familiaris 30616 R-CFA-983156 https://reactome.org/PathwayBrowser/#/R-CFA-983156 Polyubiquitination of substrate IEA Canis familiaris 30616 R-CFA-983259 https://reactome.org/PathwayBrowser/#/R-CFA-983259 Kinesins move along microtubules consuming ATP IEA Canis familiaris 30616 R-CFA-9836159 https://reactome.org/PathwayBrowser/#/R-CFA-9836159 p-PKR dimer phosphorylates DHX9 IEA Canis familiaris 30616 R-CFA-9836184 https://reactome.org/PathwayBrowser/#/R-CFA-9836184 p-PKR dimer phosphorylates CDK1 IEA Canis familiaris 30616 R-CFA-9836322 https://reactome.org/PathwayBrowser/#/R-CFA-9836322 p-PKR dimer phosphorylates MKK6 IEA Canis familiaris 30616 R-CFA-9836362 https://reactome.org/PathwayBrowser/#/R-CFA-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Canis familiaris 30616 R-CFA-9836383 https://reactome.org/PathwayBrowser/#/R-CFA-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Canis familiaris 30616 R-CFA-9836404 https://reactome.org/PathwayBrowser/#/R-CFA-9836404 p-PKR dimer phosphorylates MAPT IEA Canis familiaris 30616 R-CFA-9836435 https://reactome.org/PathwayBrowser/#/R-CFA-9836435 p-PKR dimer phosphorylates SNCA IEA Canis familiaris 30616 R-CFA-9836515 https://reactome.org/PathwayBrowser/#/R-CFA-9836515 p-PKR dimer phosphorylates PTPN2 IEA Canis familiaris 30616 R-CFA-9836617 https://reactome.org/PathwayBrowser/#/R-CFA-9836617 p-PKR dimer phosphorylates SPHK1 IEA Canis familiaris 30616 R-CFA-9836664 https://reactome.org/PathwayBrowser/#/R-CFA-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Canis familiaris 30616 R-CFA-983703 https://reactome.org/PathwayBrowser/#/R-CFA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Canis familiaris 30616 R-CFA-983707 https://reactome.org/PathwayBrowser/#/R-CFA-983707 SYK autophosphorylates at the activated BCR IEA Canis familiaris 30616 R-CFA-9837337 https://reactome.org/PathwayBrowser/#/R-CFA-9837337 DCAKD phosphorylates DP-CoA IEA Canis familiaris 30616 R-CFA-9838004 https://reactome.org/PathwayBrowser/#/R-CFA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Canis familiaris 30616 R-CFA-9838081 https://reactome.org/PathwayBrowser/#/R-CFA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Canis familiaris 30616 R-CFA-9838289 https://reactome.org/PathwayBrowser/#/R-CFA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Canis familiaris 30616 R-CFA-9838321 https://reactome.org/PathwayBrowser/#/R-CFA-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Canis familiaris 30616 R-CFA-9839059 https://reactome.org/PathwayBrowser/#/R-CFA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Canis familiaris 30616 R-CFA-9839105 https://reactome.org/PathwayBrowser/#/R-CFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Canis familiaris 30616 R-CFA-9839113 https://reactome.org/PathwayBrowser/#/R-CFA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Canis familiaris 30616 R-CFA-9840564 https://reactome.org/PathwayBrowser/#/R-CFA-9840564 OMA1 hydrolyzes YME1L1 IEA Canis familiaris 30616 R-CFA-9843721 https://reactome.org/PathwayBrowser/#/R-CFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Canis familiaris 30616 R-CFA-9851972 https://reactome.org/PathwayBrowser/#/R-CFA-9851972 PLK1 phosphorylates FIRRM at S43 IEA Canis familiaris 30616 R-CFA-9853369 https://reactome.org/PathwayBrowser/#/R-CFA-9853369 PLK1 phosphorylates FIRMM at S744 IEA Canis familiaris 30616 R-CFA-9861642 https://reactome.org/PathwayBrowser/#/R-CFA-9861642 NEK1 phosphorylates ME1 IEA Canis familiaris 30616 R-CFA-994137 https://reactome.org/PathwayBrowser/#/R-CFA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Canis familiaris 30616 R-CFA-994140 https://reactome.org/PathwayBrowser/#/R-CFA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Canis familiaris 30616 R-DDI-109624 https://reactome.org/PathwayBrowser/#/R-DDI-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Dictyostelium discoideum 30616 R-DDI-109702 https://reactome.org/PathwayBrowser/#/R-DDI-109702 PDPK1 phosphorylates AKT2 IEA Dictyostelium discoideum 30616 R-DDI-109860 https://reactome.org/PathwayBrowser/#/R-DDI-109860 MAP2K1 phosphorylates MAPK3 IEA Dictyostelium discoideum 30616 R-DDI-109862 https://reactome.org/PathwayBrowser/#/R-DDI-109862 MAP2K2 phosphorylates MAPK1 IEA Dictyostelium discoideum 30616 R-DDI-109903 https://reactome.org/PathwayBrowser/#/R-DDI-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Dictyostelium discoideum 30616 R-DDI-110133 https://reactome.org/PathwayBrowser/#/R-DDI-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Dictyostelium discoideum 30616 R-DDI-110144 https://reactome.org/PathwayBrowser/#/R-DDI-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Dictyostelium discoideum 30616 R-DDI-110145 https://reactome.org/PathwayBrowser/#/R-DDI-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Dictyostelium discoideum 30616 R-DDI-111751 https://reactome.org/PathwayBrowser/#/R-DDI-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 30616 R-DDI-111804 https://reactome.org/PathwayBrowser/#/R-DDI-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 30616 R-DDI-111915 https://reactome.org/PathwayBrowser/#/R-DDI-111915 CAMK4 autophosphorylates IEA Dictyostelium discoideum 30616 R-DDI-111930 https://reactome.org/PathwayBrowser/#/R-DDI-111930 Adenylate cyclase produces cAMP IEA Dictyostelium discoideum 30616 R-DDI-114683 https://reactome.org/PathwayBrowser/#/R-DDI-114683 Phosphorylation of Platelet Sec-1 IEA Dictyostelium discoideum 30616 R-DDI-114684 https://reactome.org/PathwayBrowser/#/R-DDI-114684 Phosphorylation of Syntaxin-4 IEA Dictyostelium discoideum 30616 R-DDI-1169397 https://reactome.org/PathwayBrowser/#/R-DDI-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Dictyostelium discoideum 30616 R-DDI-1169398 https://reactome.org/PathwayBrowser/#/R-DDI-1169398 ISGylation of host protein filamin B IEA Dictyostelium discoideum 30616 R-DDI-1169402 https://reactome.org/PathwayBrowser/#/R-DDI-1169402 ISGylation of E2 conjugating enzymes IEA Dictyostelium discoideum 30616 R-DDI-1169406 https://reactome.org/PathwayBrowser/#/R-DDI-1169406 ISGylation of host proteins IEA Dictyostelium discoideum 30616 R-DDI-1247935 https://reactome.org/PathwayBrowser/#/R-DDI-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Dictyostelium discoideum 30616 R-DDI-1247960 https://reactome.org/PathwayBrowser/#/R-DDI-1247960 Activation of p38 MAPK IEA Dictyostelium discoideum 30616 R-DDI-1358791 https://reactome.org/PathwayBrowser/#/R-DDI-1358791 Phosphorylation of USP8 by P-AKT IEA Dictyostelium discoideum 30616 R-DDI-1369028 https://reactome.org/PathwayBrowser/#/R-DDI-1369028 ABCAs mediate lipid efflux IEA Dictyostelium discoideum 30616 R-DDI-1369052 https://reactome.org/PathwayBrowser/#/R-DDI-1369052 ABCAs mediate lipid influx IEA Dictyostelium discoideum 30616 R-DDI-139855 https://reactome.org/PathwayBrowser/#/R-DDI-139855 P2X1-mediated entry of Ca++ from plasma IEA Dictyostelium discoideum 30616 R-DDI-1454916 https://reactome.org/PathwayBrowser/#/R-DDI-1454916 The ABCC family mediates organic anion transport IEA Dictyostelium discoideum 30616 R-DDI-1454928 https://reactome.org/PathwayBrowser/#/R-DDI-1454928 ABCG4 may mediate cholesterol efflux IEA Dictyostelium discoideum 30616 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-1467466 https://reactome.org/PathwayBrowser/#/R-DDI-1467466 ABCA4 mediates atRAL transport IEA Dictyostelium discoideum 30616 R-DDI-1483222 https://reactome.org/PathwayBrowser/#/R-DDI-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Dictyostelium discoideum 30616 R-DDI-156678 https://reactome.org/PathwayBrowser/#/R-DDI-156678 Activation of Cdc25C IEA Dictyostelium discoideum 30616 R-DDI-156682 https://reactome.org/PathwayBrowser/#/R-DDI-156682 PLK1 phosphorylates NUDC IEA Dictyostelium discoideum 30616 R-DDI-156699 https://reactome.org/PathwayBrowser/#/R-DDI-156699 Inactivation of Wee1 kinase IEA Dictyostelium discoideum 30616 R-DDI-162657 https://reactome.org/PathwayBrowser/#/R-DDI-162657 Inactivation of Myt1 kinase IEA Dictyostelium discoideum 30616 R-DDI-163215 https://reactome.org/PathwayBrowser/#/R-DDI-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Dictyostelium discoideum 30616 R-DDI-165162 https://reactome.org/PathwayBrowser/#/R-DDI-165162 Phosphorylation of TSC2 by PKB IEA Dictyostelium discoideum 30616 R-DDI-165692 https://reactome.org/PathwayBrowser/#/R-DDI-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Dictyostelium discoideum 30616 R-DDI-165718 https://reactome.org/PathwayBrowser/#/R-DDI-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Dictyostelium discoideum 30616 R-DDI-165726 https://reactome.org/PathwayBrowser/#/R-DDI-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Dictyostelium discoideum 30616 R-DDI-165758 https://reactome.org/PathwayBrowser/#/R-DDI-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Dictyostelium discoideum 30616 R-DDI-165766 https://reactome.org/PathwayBrowser/#/R-DDI-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Dictyostelium discoideum 30616 R-DDI-1675773 https://reactome.org/PathwayBrowser/#/R-DDI-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Dictyostelium discoideum 30616 R-DDI-1675776 https://reactome.org/PathwayBrowser/#/R-DDI-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Dictyostelium discoideum 30616 R-DDI-1675810 https://reactome.org/PathwayBrowser/#/R-DDI-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Dictyostelium discoideum 30616 R-DDI-1675813 https://reactome.org/PathwayBrowser/#/R-DDI-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Dictyostelium discoideum 30616 R-DDI-1675883 https://reactome.org/PathwayBrowser/#/R-DDI-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Dictyostelium discoideum 30616 R-DDI-1675928 https://reactome.org/PathwayBrowser/#/R-DDI-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Dictyostelium discoideum 30616 R-DDI-1675939 https://reactome.org/PathwayBrowser/#/R-DDI-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Dictyostelium discoideum 30616 R-DDI-1675961 https://reactome.org/PathwayBrowser/#/R-DDI-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Dictyostelium discoideum 30616 R-DDI-1676024 https://reactome.org/PathwayBrowser/#/R-DDI-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Dictyostelium discoideum 30616 R-DDI-1676048 https://reactome.org/PathwayBrowser/#/R-DDI-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Dictyostelium discoideum 30616 R-DDI-1676082 https://reactome.org/PathwayBrowser/#/R-DDI-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Dictyostelium discoideum 30616 R-DDI-1676109 https://reactome.org/PathwayBrowser/#/R-DDI-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Dictyostelium discoideum 30616 R-DDI-1676134 https://reactome.org/PathwayBrowser/#/R-DDI-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Dictyostelium discoideum 30616 R-DDI-1676145 https://reactome.org/PathwayBrowser/#/R-DDI-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Dictyostelium discoideum 30616 R-DDI-1676185 https://reactome.org/PathwayBrowser/#/R-DDI-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Dictyostelium discoideum 30616 R-DDI-1676206 https://reactome.org/PathwayBrowser/#/R-DDI-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Dictyostelium discoideum 30616 R-DDI-168162 https://reactome.org/PathwayBrowser/#/R-DDI-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Dictyostelium discoideum 30616 R-DDI-170676 https://reactome.org/PathwayBrowser/#/R-DDI-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Dictyostelium discoideum 30616 R-DDI-174079 https://reactome.org/PathwayBrowser/#/R-DDI-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Dictyostelium discoideum 30616 R-DDI-174391 https://reactome.org/PathwayBrowser/#/R-DDI-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Dictyostelium discoideum 30616 R-DDI-174394 https://reactome.org/PathwayBrowser/#/R-DDI-174394 GSS:Mg2+ dimer synthesizes GSH IEA Dictyostelium discoideum 30616 R-DDI-1855153 https://reactome.org/PathwayBrowser/#/R-DDI-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-1855157 https://reactome.org/PathwayBrowser/#/R-DDI-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 30616 R-DDI-1855158 https://reactome.org/PathwayBrowser/#/R-DDI-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-1855162 https://reactome.org/PathwayBrowser/#/R-DDI-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-1855169 https://reactome.org/PathwayBrowser/#/R-DDI-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-1855172 https://reactome.org/PathwayBrowser/#/R-DDI-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-1855181 https://reactome.org/PathwayBrowser/#/R-DDI-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 30616 R-DDI-1855185 https://reactome.org/PathwayBrowser/#/R-DDI-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 30616 R-DDI-1855193 https://reactome.org/PathwayBrowser/#/R-DDI-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-1855194 https://reactome.org/PathwayBrowser/#/R-DDI-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-1855197 https://reactome.org/PathwayBrowser/#/R-DDI-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-1855206 https://reactome.org/PathwayBrowser/#/R-DDI-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 30616 R-DDI-1855207 https://reactome.org/PathwayBrowser/#/R-DDI-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 30616 R-DDI-1855223 https://reactome.org/PathwayBrowser/#/R-DDI-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-1855224 https://reactome.org/PathwayBrowser/#/R-DDI-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 30616 R-DDI-1855227 https://reactome.org/PathwayBrowser/#/R-DDI-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-1855228 https://reactome.org/PathwayBrowser/#/R-DDI-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 30616 R-DDI-1855230 https://reactome.org/PathwayBrowser/#/R-DDI-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 30616 R-DDI-1855233 https://reactome.org/PathwayBrowser/#/R-DDI-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Dictyostelium discoideum 30616 R-DDI-191380 https://reactome.org/PathwayBrowser/#/R-DDI-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Dictyostelium discoideum 30616 R-DDI-191414 https://reactome.org/PathwayBrowser/#/R-DDI-191414 MVD decarboxylates MVA5PP to IPPP IEA Dictyostelium discoideum 30616 R-DDI-193362 https://reactome.org/PathwayBrowser/#/R-DDI-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-194153 https://reactome.org/PathwayBrowser/#/R-DDI-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-196753 https://reactome.org/PathwayBrowser/#/R-DDI-196753 2xPPCS ligates PPanK with Cys IEA Dictyostelium discoideum 30616 R-DDI-196754 https://reactome.org/PathwayBrowser/#/R-DDI-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Dictyostelium discoideum 30616 R-DDI-196761 https://reactome.org/PathwayBrowser/#/R-DDI-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Dictyostelium discoideum 30616 R-DDI-196773 https://reactome.org/PathwayBrowser/#/R-DDI-196773 COASY phosphorylates DP-CoA IEA Dictyostelium discoideum 30616 R-DDI-196929 https://reactome.org/PathwayBrowser/#/R-DDI-196929 FLAD1 phosphorylates FMN IEA Dictyostelium discoideum 30616 R-DDI-197198 https://reactome.org/PathwayBrowser/#/R-DDI-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Dictyostelium discoideum 30616 R-DDI-197235 https://reactome.org/PathwayBrowser/#/R-DDI-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 30616 R-DDI-197271 https://reactome.org/PathwayBrowser/#/R-DDI-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Dictyostelium discoideum 30616 R-DDI-197958 https://reactome.org/PathwayBrowser/#/R-DDI-197958 FPGS-2 transforms THF to THFPG IEA Dictyostelium discoideum 30616 R-DDI-198314 https://reactome.org/PathwayBrowser/#/R-DDI-198314 DAG stimulates protein kinase C-delta IEA Dictyostelium discoideum 30616 R-DDI-198609 https://reactome.org/PathwayBrowser/#/R-DDI-198609 AKT phosphorylates TSC2, inhibiting it IEA Dictyostelium discoideum 30616 R-DDI-198640 https://reactome.org/PathwayBrowser/#/R-DDI-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Dictyostelium discoideum 30616 R-DDI-198669 https://reactome.org/PathwayBrowser/#/R-DDI-198669 p38MAPK phosphorylates MSK1 IEA Dictyostelium discoideum 30616 R-DDI-198746 https://reactome.org/PathwayBrowser/#/R-DDI-198746 ERK1/2/5 activate RSK1/2/3 IEA Dictyostelium discoideum 30616 R-DDI-198756 https://reactome.org/PathwayBrowser/#/R-DDI-198756 ERK1/2 phosphorylates MSK1 IEA Dictyostelium discoideum 30616 R-DDI-199839 https://reactome.org/PathwayBrowser/#/R-DDI-199839 AKT can phosphorylate RSK IEA Dictyostelium discoideum 30616 R-DDI-200423 https://reactome.org/PathwayBrowser/#/R-DDI-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Dictyostelium discoideum 30616 R-DDI-200474 https://reactome.org/PathwayBrowser/#/R-DDI-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 30616 R-DDI-200512 https://reactome.org/PathwayBrowser/#/R-DDI-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 30616 R-DDI-200555 https://reactome.org/PathwayBrowser/#/R-DDI-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Dictyostelium discoideum 30616 R-DDI-200681 https://reactome.org/PathwayBrowser/#/R-DDI-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Dictyostelium discoideum 30616 R-DDI-200682 https://reactome.org/PathwayBrowser/#/R-DDI-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Dictyostelium discoideum 30616 R-DDI-200711 https://reactome.org/PathwayBrowser/#/R-DDI-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Dictyostelium discoideum 30616 R-DDI-201035 https://reactome.org/PathwayBrowser/#/R-DDI-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Dictyostelium discoideum 30616 R-DDI-202111 https://reactome.org/PathwayBrowser/#/R-DDI-202111 AKT1 phosphorylates eNOS IEA Dictyostelium discoideum 30616 R-DDI-202222 https://reactome.org/PathwayBrowser/#/R-DDI-202222 Phosphorylation of PKC theta IEA Dictyostelium discoideum 30616 R-DDI-2029454 https://reactome.org/PathwayBrowser/#/R-DDI-2029454 Autophosphorylation of PAK1 IEA Dictyostelium discoideum 30616 R-DDI-2029460 https://reactome.org/PathwayBrowser/#/R-DDI-2029460 PAK1 phosphorylates LIMK1 IEA Dictyostelium discoideum 30616 R-DDI-2029466 https://reactome.org/PathwayBrowser/#/R-DDI-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Dictyostelium discoideum 30616 R-DDI-2029469 https://reactome.org/PathwayBrowser/#/R-DDI-2029469 p-ERK phosphorylates WAVEs and ABI IEA Dictyostelium discoideum 30616 R-DDI-2029473 https://reactome.org/PathwayBrowser/#/R-DDI-2029473 Branching and elongation of mother and daughter filaments IEA Dictyostelium discoideum 30616 R-DDI-2046085 https://reactome.org/PathwayBrowser/#/R-DDI-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Dictyostelium discoideum 30616 R-DDI-2046087 https://reactome.org/PathwayBrowser/#/R-DDI-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Dictyostelium discoideum 30616 R-DDI-2046093 https://reactome.org/PathwayBrowser/#/R-DDI-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Dictyostelium discoideum 30616 R-DDI-2046098 https://reactome.org/PathwayBrowser/#/R-DDI-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Dictyostelium discoideum 30616 R-DDI-205136 https://reactome.org/PathwayBrowser/#/R-DDI-205136 GTP-bound RAC contributes to JNK activation IEA Dictyostelium discoideum 30616 R-DDI-2197690 https://reactome.org/PathwayBrowser/#/R-DDI-2197690 Detachment of WASP/WAVE IEA Dictyostelium discoideum 30616 R-DDI-2214351 https://reactome.org/PathwayBrowser/#/R-DDI-2214351 PLK1 phosphorylates GORASP1 IEA Dictyostelium discoideum 30616 R-DDI-2267372 https://reactome.org/PathwayBrowser/#/R-DDI-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Dictyostelium discoideum 30616 R-DDI-2294580 https://reactome.org/PathwayBrowser/#/R-DDI-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Dictyostelium discoideum 30616 R-DDI-2408551 https://reactome.org/PathwayBrowser/#/R-DDI-2408551 SeMet is converted to AdoSeMet by MAT IEA Dictyostelium discoideum 30616 R-DDI-2466068 https://reactome.org/PathwayBrowser/#/R-DDI-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Dictyostelium discoideum 30616 R-DDI-2529020 https://reactome.org/PathwayBrowser/#/R-DDI-2529020 CK2 phosphorylates condensin I subunits IEA Dictyostelium discoideum 30616 R-DDI-265783 https://reactome.org/PathwayBrowser/#/R-DDI-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-266082 https://reactome.org/PathwayBrowser/#/R-DDI-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Dictyostelium discoideum 30616 R-DDI-2730835 https://reactome.org/PathwayBrowser/#/R-DDI-2730835 Autophosphorylation of PKC-theta IEA Dictyostelium discoideum 30616 R-DDI-2730868 https://reactome.org/PathwayBrowser/#/R-DDI-2730868 Phosphorylation of MEK7 by MEKK1 IEA Dictyostelium discoideum 30616 R-DDI-2730896 https://reactome.org/PathwayBrowser/#/R-DDI-2730896 Phosphorylation of MEK4 by MEKK1 IEA Dictyostelium discoideum 30616 R-DDI-2990833 https://reactome.org/PathwayBrowser/#/R-DDI-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Dictyostelium discoideum 30616 R-DDI-2993447 https://reactome.org/PathwayBrowser/#/R-DDI-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Dictyostelium discoideum 30616 R-DDI-2993799 https://reactome.org/PathwayBrowser/#/R-DDI-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Dictyostelium discoideum 30616 R-DDI-2993814 https://reactome.org/PathwayBrowser/#/R-DDI-2993814 HLCS biotinylates ACACA:Mn2+ IEA Dictyostelium discoideum 30616 R-DDI-3095901 https://reactome.org/PathwayBrowser/#/R-DDI-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-3159253 https://reactome.org/PathwayBrowser/#/R-DDI-3159253 MMAB adenosylates cob(I)alamin IEA Dictyostelium discoideum 30616 R-DDI-3249379 https://reactome.org/PathwayBrowser/#/R-DDI-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Dictyostelium discoideum 30616 R-DDI-3371422 https://reactome.org/PathwayBrowser/#/R-DDI-3371422 ATP hydrolysis by HSP70 IEA Dictyostelium discoideum 30616 R-DDI-3371435 https://reactome.org/PathwayBrowser/#/R-DDI-3371435 Constitutive phosphorylation by GSK3 IEA Dictyostelium discoideum 30616 R-DDI-3371531 https://reactome.org/PathwayBrowser/#/R-DDI-3371531 Constitutive phosphorylation by pERK1/2 IEA Dictyostelium discoideum 30616 R-DDI-3371590 https://reactome.org/PathwayBrowser/#/R-DDI-3371590 HSP70 binds to HSP40:nascent protein IEA Dictyostelium discoideum 30616 R-DDI-349444 https://reactome.org/PathwayBrowser/#/R-DDI-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Dictyostelium discoideum 30616 R-DDI-377186 https://reactome.org/PathwayBrowser/#/R-DDI-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Dictyostelium discoideum 30616 R-DDI-3788705 https://reactome.org/PathwayBrowser/#/R-DDI-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Dictyostelium discoideum 30616 R-DDI-381091 https://reactome.org/PathwayBrowser/#/R-DDI-381091 IRE1 dimer autophosphorylates IEA Dictyostelium discoideum 30616 R-DDI-382560 https://reactome.org/PathwayBrowser/#/R-DDI-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Dictyostelium discoideum 30616 R-DDI-382575 https://reactome.org/PathwayBrowser/#/R-DDI-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Dictyostelium discoideum 30616 R-DDI-383190 https://reactome.org/PathwayBrowser/#/R-DDI-383190 HCO3- transport through ion channel IEA Dictyostelium discoideum 30616 R-DDI-389652 https://reactome.org/PathwayBrowser/#/R-DDI-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Dictyostelium discoideum 30616 R-DDI-392300 https://reactome.org/PathwayBrowser/#/R-DDI-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Dictyostelium discoideum 30616 R-DDI-3928620 https://reactome.org/PathwayBrowser/#/R-DDI-3928620 PAK1 autophosphorylates IEA Dictyostelium discoideum 30616 R-DDI-4167511 https://reactome.org/PathwayBrowser/#/R-DDI-4167511 HLCS biotinylates ACACB IEA Dictyostelium discoideum 30616 R-DDI-419490 https://reactome.org/PathwayBrowser/#/R-DDI-419490 Binding of ATP to P2X receptors IEA Dictyostelium discoideum 30616 R-DDI-419644 https://reactome.org/PathwayBrowser/#/R-DDI-419644 Transphosphorylation of pLIMK1 IEA Dictyostelium discoideum 30616 R-DDI-426240 https://reactome.org/PathwayBrowser/#/R-DDI-426240 DAG kinase produces phosphatidic acid from DAG IEA Dictyostelium discoideum 30616 R-DDI-428273 https://reactome.org/PathwayBrowser/#/R-DDI-428273 SPHK1 phosphorylates sphingoid IEA Dictyostelium discoideum 30616 R-DDI-428941 https://reactome.org/PathwayBrowser/#/R-DDI-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Dictyostelium discoideum 30616 R-DDI-429157 https://reactome.org/PathwayBrowser/#/R-DDI-429157 ABCC4 accumulation of dense granule contents IEA Dictyostelium discoideum 30616 R-DDI-430347 https://reactome.org/PathwayBrowser/#/R-DDI-430347 MigFilin associates with Filamin and F-actin IEA Dictyostelium discoideum 30616 R-DDI-437162 https://reactome.org/PathwayBrowser/#/R-DDI-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Dictyostelium discoideum 30616 R-DDI-445072 https://reactome.org/PathwayBrowser/#/R-DDI-445072 Interaction of PAK1 with Rac1-GTP IEA Dictyostelium discoideum 30616 R-DDI-445079 https://reactome.org/PathwayBrowser/#/R-DDI-445079 Phosphorylation of L1 by ERK IEA Dictyostelium discoideum 30616 R-DDI-447074 https://reactome.org/PathwayBrowser/#/R-DDI-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Dictyostelium discoideum 30616 R-DDI-448955 https://reactome.org/PathwayBrowser/#/R-DDI-448955 Phosphorylation of MEF2 proteins by p38 IEA Dictyostelium discoideum 30616 R-DDI-449911 https://reactome.org/PathwayBrowser/#/R-DDI-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Dictyostelium discoideum 30616 R-DDI-450088 https://reactome.org/PathwayBrowser/#/R-DDI-450088 GLUT1 tetramer binds 4xATP IEA Dictyostelium discoideum 30616 R-DDI-450092 https://reactome.org/PathwayBrowser/#/R-DDI-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Dictyostelium discoideum 30616 R-DDI-450490 https://reactome.org/PathwayBrowser/#/R-DDI-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Dictyostelium discoideum 30616 R-DDI-453342 https://reactome.org/PathwayBrowser/#/R-DDI-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Dictyostelium discoideum 30616 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 30616 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 30616 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 30616 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 30616 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 30616 R-DDI-504054 https://reactome.org/PathwayBrowser/#/R-DDI-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Dictyostelium discoideum 30616 R-DDI-5082405 https://reactome.org/PathwayBrowser/#/R-DDI-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Dictyostelium discoideum 30616 R-DDI-508308 https://reactome.org/PathwayBrowser/#/R-DDI-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Dictyostelium discoideum 30616 R-DDI-5218805 https://reactome.org/PathwayBrowser/#/R-DDI-5218805 PKC autophosphorylates IEA Dictyostelium discoideum 30616 R-DDI-5218821 https://reactome.org/PathwayBrowser/#/R-DDI-5218821 PDK1 phosphorylates PKC IEA Dictyostelium discoideum 30616 R-DDI-5218823 https://reactome.org/PathwayBrowser/#/R-DDI-5218823 PKC phosphorylates sphingosine kinase 1 IEA Dictyostelium discoideum 30616 R-DDI-5223313 https://reactome.org/PathwayBrowser/#/R-DDI-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Dictyostelium discoideum 30616 R-DDI-5251942 https://reactome.org/PathwayBrowser/#/R-DDI-5251942 Hikeshi binds HSP70s:ATP IEA Dictyostelium discoideum 30616 R-DDI-5251955 https://reactome.org/PathwayBrowser/#/R-DDI-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Dictyostelium discoideum 30616 R-DDI-5251959 https://reactome.org/PathwayBrowser/#/R-DDI-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-5251989 https://reactome.org/PathwayBrowser/#/R-DDI-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Dictyostelium discoideum 30616 R-DDI-5252079 https://reactome.org/PathwayBrowser/#/R-DDI-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Dictyostelium discoideum 30616 R-DDI-5339524 https://reactome.org/PathwayBrowser/#/R-DDI-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 30616 R-DDI-5358475 https://reactome.org/PathwayBrowser/#/R-DDI-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Dictyostelium discoideum 30616 R-DDI-5358510 https://reactome.org/PathwayBrowser/#/R-DDI-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Dictyostelium discoideum 30616 R-DDI-5358518 https://reactome.org/PathwayBrowser/#/R-DDI-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Dictyostelium discoideum 30616 R-DDI-5358592 https://reactome.org/PathwayBrowser/#/R-DDI-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Dictyostelium discoideum 30616 R-DDI-5358597 https://reactome.org/PathwayBrowser/#/R-DDI-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Dictyostelium discoideum 30616 R-DDI-5358912 https://reactome.org/PathwayBrowser/#/R-DDI-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Dictyostelium discoideum 30616 R-DDI-5603114 https://reactome.org/PathwayBrowser/#/R-DDI-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Dictyostelium discoideum 30616 R-DDI-5610727 https://reactome.org/PathwayBrowser/#/R-DDI-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Dictyostelium discoideum 30616 R-DDI-5618107 https://reactome.org/PathwayBrowser/#/R-DDI-5618107 ATP binding to HSP90 triggers conformation change IEA Dictyostelium discoideum 30616 R-DDI-5625784 https://reactome.org/PathwayBrowser/#/R-DDI-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Dictyostelium discoideum 30616 R-DDI-5626507 https://reactome.org/PathwayBrowser/#/R-DDI-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Dictyostelium discoideum 30616 R-DDI-5627775 https://reactome.org/PathwayBrowser/#/R-DDI-5627775 Autophosphorylation of PAK1,2,3 IEA Dictyostelium discoideum 30616 R-DDI-5665868 https://reactome.org/PathwayBrowser/#/R-DDI-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Dictyostelium discoideum 30616 R-DDI-5668932 https://reactome.org/PathwayBrowser/#/R-DDI-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Dictyostelium discoideum 30616 R-DDI-5669250 https://reactome.org/PathwayBrowser/#/R-DDI-5669250 PAK1 phosphorylates FLNA IEA Dictyostelium discoideum 30616 R-DDI-5671749 https://reactome.org/PathwayBrowser/#/R-DDI-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Dictyostelium discoideum 30616 R-DDI-5672008 https://reactome.org/PathwayBrowser/#/R-DDI-5672008 Thr-180 of ULK1 is phosphorylated IEA Dictyostelium discoideum 30616 R-DDI-5672010 https://reactome.org/PathwayBrowser/#/R-DDI-5672010 Active MTORC1 phosphorylates ULK1 IEA Dictyostelium discoideum 30616 R-DDI-5672012 https://reactome.org/PathwayBrowser/#/R-DDI-5672012 Beclin-1 complex phosphorylates PtdIns IEA Dictyostelium discoideum 30616 R-DDI-5672828 https://reactome.org/PathwayBrowser/#/R-DDI-5672828 mTORC1 phosphorylates AKT1S1 IEA Dictyostelium discoideum 30616 R-DDI-5672948 https://reactome.org/PathwayBrowser/#/R-DDI-5672948 MARK3 phosphorylates KSR1 IEA Dictyostelium discoideum 30616 R-DDI-5673768 https://reactome.org/PathwayBrowser/#/R-DDI-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Dictyostelium discoideum 30616 R-DDI-5674130 https://reactome.org/PathwayBrowser/#/R-DDI-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Dictyostelium discoideum 30616 R-DDI-5674373 https://reactome.org/PathwayBrowser/#/R-DDI-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Dictyostelium discoideum 30616 R-DDI-5674496 https://reactome.org/PathwayBrowser/#/R-DDI-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Dictyostelium discoideum 30616 R-DDI-5675868 https://reactome.org/PathwayBrowser/#/R-DDI-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Dictyostelium discoideum 30616 R-DDI-5678706 https://reactome.org/PathwayBrowser/#/R-DDI-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-5678863 https://reactome.org/PathwayBrowser/#/R-DDI-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-5679041 https://reactome.org/PathwayBrowser/#/R-DDI-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-5679205 https://reactome.org/PathwayBrowser/#/R-DDI-5679205 ULK1 phosphorylates Beclin-1 IEA Dictyostelium discoideum 30616 R-DDI-5682026 https://reactome.org/PathwayBrowser/#/R-DDI-5682026 MRN bound to shortened telomeres activates ATM IEA Dictyostelium discoideum 30616 R-DDI-5682285 https://reactome.org/PathwayBrowser/#/R-DDI-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-5682983 https://reactome.org/PathwayBrowser/#/R-DDI-5682983 ATM phosphorylates WHSC1 IEA Dictyostelium discoideum 30616 R-DDI-5683425 https://reactome.org/PathwayBrowser/#/R-DDI-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Dictyostelium discoideum 30616 R-DDI-5683714 https://reactome.org/PathwayBrowser/#/R-DDI-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Dictyostelium discoideum 30616 R-DDI-5683792 https://reactome.org/PathwayBrowser/#/R-DDI-5683792 p-T68-CHEK2 autophosphorylates IEA Dictyostelium discoideum 30616 R-DDI-5687086 https://reactome.org/PathwayBrowser/#/R-DDI-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Dictyostelium discoideum 30616 R-DDI-5687183 https://reactome.org/PathwayBrowser/#/R-DDI-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Dictyostelium discoideum 30616 R-DDI-5690996 https://reactome.org/PathwayBrowser/#/R-DDI-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Dictyostelium discoideum 30616 R-DDI-5692462 https://reactome.org/PathwayBrowser/#/R-DDI-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Dictyostelium discoideum 30616 R-DDI-5692480 https://reactome.org/PathwayBrowser/#/R-DDI-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Dictyostelium discoideum 30616 R-DDI-5693536 https://reactome.org/PathwayBrowser/#/R-DDI-5693536 ATM phosphorylates MDC1 IEA Dictyostelium discoideum 30616 R-DDI-5693540 https://reactome.org/PathwayBrowser/#/R-DDI-5693540 MRN activates ATM IEA Dictyostelium discoideum 30616 R-DDI-5693549 https://reactome.org/PathwayBrowser/#/R-DDI-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Dictyostelium discoideum 30616 R-DDI-5693575 https://reactome.org/PathwayBrowser/#/R-DDI-5693575 DNA-PKcs autophosphorylates IEA Dictyostelium discoideum 30616 R-DDI-5693598 https://reactome.org/PathwayBrowser/#/R-DDI-5693598 ATM phosphorylates NBN IEA Dictyostelium discoideum 30616 R-DDI-5694425 https://reactome.org/PathwayBrowser/#/R-DDI-5694425 NSF ATPase activity dissociates cis-SNARE IEA Dictyostelium discoideum 30616 R-DDI-5694441 https://reactome.org/PathwayBrowser/#/R-DDI-5694441 CSNK1D phosphorylates SEC23 IEA Dictyostelium discoideum 30616 R-DDI-5695957 https://reactome.org/PathwayBrowser/#/R-DDI-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Dictyostelium discoideum 30616 R-DDI-5696007 https://reactome.org/PathwayBrowser/#/R-DDI-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Dictyostelium discoideum 30616 R-DDI-5696074 https://reactome.org/PathwayBrowser/#/R-DDI-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Dictyostelium discoideum 30616 R-DDI-5696839 https://reactome.org/PathwayBrowser/#/R-DDI-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Dictyostelium discoideum 30616 R-DDI-6782131 https://reactome.org/PathwayBrowser/#/R-DDI-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Dictyostelium discoideum 30616 R-DDI-6787540 https://reactome.org/PathwayBrowser/#/R-DDI-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Dictyostelium discoideum 30616 R-DDI-6788798 https://reactome.org/PathwayBrowser/#/R-DDI-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 30616 R-DDI-6788810 https://reactome.org/PathwayBrowser/#/R-DDI-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 30616 R-DDI-6795290 https://reactome.org/PathwayBrowser/#/R-DDI-6795290 TORC2 complex phosphorylates SGK1 IEA Dictyostelium discoideum 30616 R-DDI-6795473 https://reactome.org/PathwayBrowser/#/R-DDI-6795473 PDPK1 phosphorylates SGK1 IEA Dictyostelium discoideum 30616 R-DDI-6797606 https://reactome.org/PathwayBrowser/#/R-DDI-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Dictyostelium discoideum 30616 R-DDI-6798174 https://reactome.org/PathwayBrowser/#/R-DDI-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Dictyostelium discoideum 30616 R-DDI-6798372 https://reactome.org/PathwayBrowser/#/R-DDI-6798372 ATM phosphorylates DYRK2 IEA Dictyostelium discoideum 30616 R-DDI-6801456 https://reactome.org/PathwayBrowser/#/R-DDI-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Dictyostelium discoideum 30616 R-DDI-6802973 https://reactome.org/PathwayBrowser/#/R-DDI-6802973 PLK3 phosphorylates CDC25C IEA Dictyostelium discoideum 30616 R-DDI-6804266 https://reactome.org/PathwayBrowser/#/R-DDI-6804266 CHEK2 phosphorylates TTC5 IEA Dictyostelium discoideum 30616 R-DDI-6804276 https://reactome.org/PathwayBrowser/#/R-DDI-6804276 ATM phosphorylates TTC5 IEA Dictyostelium discoideum 30616 R-DDI-6805640 https://reactome.org/PathwayBrowser/#/R-DDI-6805640 AKT phosphorylates KAT6A IEA Dictyostelium discoideum 30616 R-DDI-6806877 https://reactome.org/PathwayBrowser/#/R-DDI-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Dictyostelium discoideum 30616 R-DDI-6806967 https://reactome.org/PathwayBrowser/#/R-DDI-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Dictyostelium discoideum 30616 R-DDI-6807868 https://reactome.org/PathwayBrowser/#/R-DDI-6807868 GBF1 stimulates ARF nucleotide exchange IEA Dictyostelium discoideum 30616 R-DDI-6809015 https://reactome.org/PathwayBrowser/#/R-DDI-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Dictyostelium discoideum 30616 R-DDI-6810233 https://reactome.org/PathwayBrowser/#/R-DDI-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Dictyostelium discoideum 30616 R-DDI-6811422 https://reactome.org/PathwayBrowser/#/R-DDI-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Dictyostelium discoideum 30616 R-DDI-6811522 https://reactome.org/PathwayBrowser/#/R-DDI-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Dictyostelium discoideum 30616 R-DDI-6814120 https://reactome.org/PathwayBrowser/#/R-DDI-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Dictyostelium discoideum 30616 R-DDI-6814124 https://reactome.org/PathwayBrowser/#/R-DDI-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Dictyostelium discoideum 30616 R-DDI-6814559 https://reactome.org/PathwayBrowser/#/R-DDI-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Dictyostelium discoideum 30616 R-DDI-6814678 https://reactome.org/PathwayBrowser/#/R-DDI-6814678 ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN IEA Dictyostelium discoideum 30616 R-DDI-68610 https://reactome.org/PathwayBrowser/#/R-DDI-68610 Formation of ORC(2-5) complex IEA Dictyostelium discoideum 30616 R-DDI-69015 https://reactome.org/PathwayBrowser/#/R-DDI-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Dictyostelium discoideum 30616 R-DDI-69063 https://reactome.org/PathwayBrowser/#/R-DDI-69063 Loading of PCNA - Sliding Clamp Formation IEA Dictyostelium discoideum 30616 R-DDI-69608 https://reactome.org/PathwayBrowser/#/R-DDI-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Dictyostelium discoideum 30616 R-DDI-70333 https://reactome.org/PathwayBrowser/#/R-DDI-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Dictyostelium discoideum 30616 R-DDI-70349 https://reactome.org/PathwayBrowser/#/R-DDI-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 30616 R-DDI-70486 https://reactome.org/PathwayBrowser/#/R-DDI-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Dictyostelium discoideum 30616 R-DDI-70599 https://reactome.org/PathwayBrowser/#/R-DDI-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Dictyostelium discoideum 30616 R-DDI-70773 https://reactome.org/PathwayBrowser/#/R-DDI-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Dictyostelium discoideum 30616 R-DDI-70967 https://reactome.org/PathwayBrowser/#/R-DDI-70967 IDH3 complex decarboxylates isocitrate IEA Dictyostelium discoideum 30616 R-DDI-70997 https://reactome.org/PathwayBrowser/#/R-DDI-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Dictyostelium discoideum 30616 R-DDI-71031 https://reactome.org/PathwayBrowser/#/R-DDI-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Dictyostelium discoideum 30616 R-DDI-71401 https://reactome.org/PathwayBrowser/#/R-DDI-71401 OGDH dimer decarboxylates 2-OG IEA Dictyostelium discoideum 30616 R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 30616 R-DDI-71735 https://reactome.org/PathwayBrowser/#/R-DDI-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Dictyostelium discoideum 30616 R-DDI-71802 https://reactome.org/PathwayBrowser/#/R-DDI-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Dictyostelium discoideum 30616 R-DDI-71850 https://reactome.org/PathwayBrowser/#/R-DDI-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Dictyostelium discoideum 30616 R-DDI-72621 https://reactome.org/PathwayBrowser/#/R-DDI-72621 Ribosomal scanning IEA Dictyostelium discoideum 30616 R-DDI-73548 https://reactome.org/PathwayBrowser/#/R-DDI-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Dictyostelium discoideum 30616 R-DDI-73577 https://reactome.org/PathwayBrowser/#/R-DDI-73577 CAD hexamer transforms L-Gln to CAP IEA Dictyostelium discoideum 30616 R-DDI-73580 https://reactome.org/PathwayBrowser/#/R-DDI-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Dictyostelium discoideum 30616 R-DDI-73599 https://reactome.org/PathwayBrowser/#/R-DDI-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Dictyostelium discoideum 30616 R-DDI-73632 https://reactome.org/PathwayBrowser/#/R-DDI-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Dictyostelium discoideum 30616 R-DDI-73635 https://reactome.org/PathwayBrowser/#/R-DDI-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Dictyostelium discoideum 30616 R-DDI-73647 https://reactome.org/PathwayBrowser/#/R-DDI-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Dictyostelium discoideum 30616 R-DDI-73788 https://reactome.org/PathwayBrowser/#/R-DDI-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Dictyostelium discoideum 30616 R-DDI-73792 https://reactome.org/PathwayBrowser/#/R-DDI-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Dictyostelium discoideum 30616 R-DDI-73810 https://reactome.org/PathwayBrowser/#/R-DDI-73810 FGAM + ATP => AIR + ADP + Pi IEA Dictyostelium discoideum 30616 R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 30616 R-DDI-73814 https://reactome.org/PathwayBrowser/#/R-DDI-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Dictyostelium discoideum 30616 R-DDI-75125 https://reactome.org/PathwayBrowser/#/R-DDI-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Dictyostelium discoideum 30616 R-DDI-75126 https://reactome.org/PathwayBrowser/#/R-DDI-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Dictyostelium discoideum 30616 R-DDI-75809 https://reactome.org/PathwayBrowser/#/R-DDI-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Dictyostelium discoideum 30616 R-DDI-75848 https://reactome.org/PathwayBrowser/#/R-DDI-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Dictyostelium discoideum 30616 R-DDI-75851 https://reactome.org/PathwayBrowser/#/R-DDI-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 30616 R-DDI-75887 https://reactome.org/PathwayBrowser/#/R-DDI-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Dictyostelium discoideum 30616 R-DDI-75949 https://reactome.org/PathwayBrowser/#/R-DDI-75949 RNA Polymerase II Promoter Opening: First Transition IEA Dictyostelium discoideum 30616 R-DDI-77071 https://reactome.org/PathwayBrowser/#/R-DDI-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Dictyostelium discoideum 30616 R-DDI-877187 https://reactome.org/PathwayBrowser/#/R-DDI-877187 P2X7 mediates loss of intracellular K+ IEA Dictyostelium discoideum 30616 R-DDI-8847638 https://reactome.org/PathwayBrowser/#/R-DDI-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Dictyostelium discoideum 30616 R-DDI-8848053 https://reactome.org/PathwayBrowser/#/R-DDI-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Dictyostelium discoideum 30616 R-DDI-8850945 https://reactome.org/PathwayBrowser/#/R-DDI-8850945 Casein kinase II phosphorylates PTEN IEA Dictyostelium discoideum 30616 R-DDI-8852128 https://reactome.org/PathwayBrowser/#/R-DDI-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Dictyostelium discoideum 30616 R-DDI-8852131 https://reactome.org/PathwayBrowser/#/R-DDI-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Dictyostelium discoideum 30616 R-DDI-8852132 https://reactome.org/PathwayBrowser/#/R-DDI-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-8852134 https://reactome.org/PathwayBrowser/#/R-DDI-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Dictyostelium discoideum 30616 R-DDI-8856813 https://reactome.org/PathwayBrowser/#/R-DDI-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Dictyostelium discoideum 30616 R-DDI-8867370 https://reactome.org/PathwayBrowser/#/R-DDI-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Dictyostelium discoideum 30616 R-DDI-8868066 https://reactome.org/PathwayBrowser/#/R-DDI-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Dictyostelium discoideum 30616 R-DDI-8868072 https://reactome.org/PathwayBrowser/#/R-DDI-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Dictyostelium discoideum 30616 R-DDI-8869606 https://reactome.org/PathwayBrowser/#/R-DDI-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 30616 R-DDI-8869607 https://reactome.org/PathwayBrowser/#/R-DDI-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 30616 R-DDI-8869627 https://reactome.org/PathwayBrowser/#/R-DDI-8869627 NMRK2 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 30616 R-DDI-8869633 https://reactome.org/PathwayBrowser/#/R-DDI-8869633 NMRK1 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 30616 R-DDI-8875071 https://reactome.org/PathwayBrowser/#/R-DDI-8875071 ACSS3 ligates CoA to CH3COO- IEA Dictyostelium discoideum 30616 R-DDI-8876446 https://reactome.org/PathwayBrowser/#/R-DDI-8876446 p-ULK1 phosphorylates DENND3 IEA Dictyostelium discoideum 30616 R-DDI-8876889 https://reactome.org/PathwayBrowser/#/R-DDI-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 30616 R-DDI-8877691 https://reactome.org/PathwayBrowser/#/R-DDI-8877691 MAP2K6 phosphorylates PIP4K2B IEA Dictyostelium discoideum 30616 R-DDI-8933446 https://reactome.org/PathwayBrowser/#/R-DDI-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Dictyostelium discoideum 30616 R-DDI-8939959 https://reactome.org/PathwayBrowser/#/R-DDI-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Dictyostelium discoideum 30616 R-DDI-8944454 https://reactome.org/PathwayBrowser/#/R-DDI-8944454 mTORC1 phosphorylates MAF1 IEA Dictyostelium discoideum 30616 R-DDI-8948039 https://reactome.org/PathwayBrowser/#/R-DDI-8948039 FUNDC1 is phosphorylated by CK2 IEA Dictyostelium discoideum 30616 R-DDI-8948146 https://reactome.org/PathwayBrowser/#/R-DDI-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Dictyostelium discoideum 30616 R-DDI-8948757 https://reactome.org/PathwayBrowser/#/R-DDI-8948757 AKT phosphorylates MKRN1 IEA Dictyostelium discoideum 30616 R-DDI-8951648 https://reactome.org/PathwayBrowser/#/R-DDI-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Dictyostelium discoideum 30616 R-DDI-8951656 https://reactome.org/PathwayBrowser/#/R-DDI-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Dictyostelium discoideum 30616 R-DDI-8954327 https://reactome.org/PathwayBrowser/#/R-DDI-8954327 UCKL1 phosphorylates urindine, cytidine IEA Dictyostelium discoideum 30616 R-DDI-8955844 https://reactome.org/PathwayBrowser/#/R-DDI-8955844 RBKS phosphorylates ribose to R5P IEA Dictyostelium discoideum 30616 R-DDI-8959510 https://reactome.org/PathwayBrowser/#/R-DDI-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Dictyostelium discoideum 30616 R-DDI-9008043 https://reactome.org/PathwayBrowser/#/R-DDI-9008043 MAPK8 phosphorylation IEA Dictyostelium discoideum 30616 R-DDI-9009072 https://reactome.org/PathwayBrowser/#/R-DDI-9009072 STAT3 phosphorylation IEA Dictyostelium discoideum 30616 R-DDI-9012319 https://reactome.org/PathwayBrowser/#/R-DDI-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Dictyostelium discoideum 30616 R-DDI-9014741 https://reactome.org/PathwayBrowser/#/R-DDI-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Dictyostelium discoideum 30616 R-DDI-9014766 https://reactome.org/PathwayBrowser/#/R-DDI-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Dictyostelium discoideum 30616 R-DDI-917693 https://reactome.org/PathwayBrowser/#/R-DDI-917693 ESCRT Disassembly IEA Dictyostelium discoideum 30616 R-DDI-917841 https://reactome.org/PathwayBrowser/#/R-DDI-917841 Acidification of Tf:TfR1 containing endosome IEA Dictyostelium discoideum 30616 R-DDI-917979 https://reactome.org/PathwayBrowser/#/R-DDI-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-927889 https://reactome.org/PathwayBrowser/#/R-DDI-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Dictyostelium discoideum 30616 R-DDI-936895 https://reactome.org/PathwayBrowser/#/R-DDI-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Dictyostelium discoideum 30616 R-DDI-939763 https://reactome.org/PathwayBrowser/#/R-DDI-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Dictyostelium discoideum 30616 R-DDI-947531 https://reactome.org/PathwayBrowser/#/R-DDI-947531 Molybdenum ion transfer onto molybdopterin IEA Dictyostelium discoideum 30616 R-DDI-947591 https://reactome.org/PathwayBrowser/#/R-DDI-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Dictyostelium discoideum 30616 R-DDI-9606884 https://reactome.org/PathwayBrowser/#/R-DDI-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Dictyostelium discoideum 30616 R-DDI-9612509 https://reactome.org/PathwayBrowser/#/R-DDI-9612509 SGK phosphorylates SRF IEA Dictyostelium discoideum 30616 R-DDI-9613494 https://reactome.org/PathwayBrowser/#/R-DDI-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Dictyostelium discoideum 30616 R-DDI-9632858 https://reactome.org/PathwayBrowser/#/R-DDI-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Dictyostelium discoideum 30616 R-DDI-964958 https://reactome.org/PathwayBrowser/#/R-DDI-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Dictyostelium discoideum 30616 R-DDI-964962 https://reactome.org/PathwayBrowser/#/R-DDI-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Dictyostelium discoideum 30616 R-DDI-964970 https://reactome.org/PathwayBrowser/#/R-DDI-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Dictyostelium discoideum 30616 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 30616 R-DDI-9661417 https://reactome.org/PathwayBrowser/#/R-DDI-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-9668419 https://reactome.org/PathwayBrowser/#/R-DDI-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Dictyostelium discoideum 30616 R-DDI-9684118 https://reactome.org/PathwayBrowser/#/R-DDI-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Dictyostelium discoideum 30616 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 30616 R-DDI-9706390 https://reactome.org/PathwayBrowser/#/R-DDI-9706390 RHOBTB3 binds interacting proteins at trans-Golgi network IEA Dictyostelium discoideum 30616 R-DDI-9706393 https://reactome.org/PathwayBrowser/#/R-DDI-9706393 RHOBTB3 binds ATP IEA Dictyostelium discoideum 30616 R-DDI-9706399 https://reactome.org/PathwayBrowser/#/R-DDI-9706399 RHOBTB3 hydrolyzes ATP IEA Dictyostelium discoideum 30616 R-DDI-9748949 https://reactome.org/PathwayBrowser/#/R-DDI-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Dictyostelium discoideum 30616 R-DDI-9748957 https://reactome.org/PathwayBrowser/#/R-DDI-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Dictyostelium discoideum 30616 R-DDI-9748963 https://reactome.org/PathwayBrowser/#/R-DDI-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Dictyostelium discoideum 30616 R-DDI-9748969 https://reactome.org/PathwayBrowser/#/R-DDI-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Dictyostelium discoideum 30616 R-DDI-9748999 https://reactome.org/PathwayBrowser/#/R-DDI-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Dictyostelium discoideum 30616 R-DDI-9750546 https://reactome.org/PathwayBrowser/#/R-DDI-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-9750656 https://reactome.org/PathwayBrowser/#/R-DDI-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Dictyostelium discoideum 30616 R-DDI-9753278 https://reactome.org/PathwayBrowser/#/R-DDI-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 30616 R-DDI-9753283 https://reactome.org/PathwayBrowser/#/R-DDI-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 30616 R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-9754974 https://reactome.org/PathwayBrowser/#/R-DDI-9754974 ADK phosphorylates RBV IEA Dictyostelium discoideum 30616 R-DDI-9755013 https://reactome.org/PathwayBrowser/#/R-DDI-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Dictyostelium discoideum 30616 R-DDI-9759206 https://reactome.org/PathwayBrowser/#/R-DDI-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Dictyostelium discoideum 30616 R-DDI-9759454 https://reactome.org/PathwayBrowser/#/R-DDI-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Dictyostelium discoideum 30616 R-DDI-9759461 https://reactome.org/PathwayBrowser/#/R-DDI-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Dictyostelium discoideum 30616 R-DDI-9794120 https://reactome.org/PathwayBrowser/#/R-DDI-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Dictyostelium discoideum 30616 R-DDI-9794572 https://reactome.org/PathwayBrowser/#/R-DDI-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Dictyostelium discoideum 30616 R-DDI-9825759 https://reactome.org/PathwayBrowser/#/R-DDI-9825759 MAPK-dependent phosphorylation of KARS IEA Dictyostelium discoideum 30616 R-DDI-983140 https://reactome.org/PathwayBrowser/#/R-DDI-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Dictyostelium discoideum 30616 R-DDI-983153 https://reactome.org/PathwayBrowser/#/R-DDI-983153 E1 mediated ubiquitin activation IEA Dictyostelium discoideum 30616 R-DDI-983156 https://reactome.org/PathwayBrowser/#/R-DDI-983156 Polyubiquitination of substrate IEA Dictyostelium discoideum 30616 R-DDI-9838004 https://reactome.org/PathwayBrowser/#/R-DDI-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Dictyostelium discoideum 30616 R-DDI-9838081 https://reactome.org/PathwayBrowser/#/R-DDI-9838081 LONP1 degrades mitochondrial matrix proteins IEA Dictyostelium discoideum 30616 R-DDI-9839105 https://reactome.org/PathwayBrowser/#/R-DDI-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Dictyostelium discoideum 30616 R-DDI-9839113 https://reactome.org/PathwayBrowser/#/R-DDI-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Dictyostelium discoideum 30616 R-DDI-9840564 https://reactome.org/PathwayBrowser/#/R-DDI-9840564 OMA1 hydrolyzes YME1L1 IEA Dictyostelium discoideum 30616 R-DDI-9843721 https://reactome.org/PathwayBrowser/#/R-DDI-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Dictyostelium discoideum 30616 R-DDI-994137 https://reactome.org/PathwayBrowser/#/R-DDI-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Dictyostelium discoideum 30616 R-DDI-994140 https://reactome.org/PathwayBrowser/#/R-DDI-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Dictyostelium discoideum 30616 R-DME-109624 https://reactome.org/PathwayBrowser/#/R-DME-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Drosophila melanogaster 30616 R-DME-109699 https://reactome.org/PathwayBrowser/#/R-DME-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-109702 https://reactome.org/PathwayBrowser/#/R-DME-109702 PDPK1 phosphorylates AKT2 IEA Drosophila melanogaster 30616 R-DME-109759 https://reactome.org/PathwayBrowser/#/R-DME-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Drosophila melanogaster 30616 R-DME-109822 https://reactome.org/PathwayBrowser/#/R-DME-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Drosophila melanogaster 30616 R-DME-109823 https://reactome.org/PathwayBrowser/#/R-DME-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Drosophila melanogaster 30616 R-DME-109860 https://reactome.org/PathwayBrowser/#/R-DME-109860 MAP2K1 phosphorylates MAPK3 IEA Drosophila melanogaster 30616 R-DME-109862 https://reactome.org/PathwayBrowser/#/R-DME-109862 MAP2K2 phosphorylates MAPK1 IEA Drosophila melanogaster 30616 R-DME-109903 https://reactome.org/PathwayBrowser/#/R-DME-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Drosophila melanogaster 30616 R-DME-110133 https://reactome.org/PathwayBrowser/#/R-DME-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Drosophila melanogaster 30616 R-DME-110137 https://reactome.org/PathwayBrowser/#/R-DME-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Drosophila melanogaster 30616 R-DME-110138 https://reactome.org/PathwayBrowser/#/R-DME-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 30616 R-DME-110141 https://reactome.org/PathwayBrowser/#/R-DME-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Drosophila melanogaster 30616 R-DME-110144 https://reactome.org/PathwayBrowser/#/R-DME-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Drosophila melanogaster 30616 R-DME-110145 https://reactome.org/PathwayBrowser/#/R-DME-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Drosophila melanogaster 30616 R-DME-110440 https://reactome.org/PathwayBrowser/#/R-DME-110440 Autophosphorylation of DINR TAS Drosophila melanogaster 30616 R-DME-110453 https://reactome.org/PathwayBrowser/#/R-DME-110453 Phosphorylation of PIP2 to PIP3 by Dp110 TAS Drosophila melanogaster 30616 R-DME-110468 https://reactome.org/PathwayBrowser/#/R-DME-110468 Activation of DAkt1 by DPDK1 TAS Drosophila melanogaster 30616 R-DME-110475 https://reactome.org/PathwayBrowser/#/R-DME-110475 DAkt1-mediated phosphorylation inactivates DFOXO TAS Drosophila melanogaster 30616 R-DME-110498 https://reactome.org/PathwayBrowser/#/R-DME-110498 DTOR is positively regulated by DRheb-GTP TAS Drosophila melanogaster 30616 R-DME-110506 https://reactome.org/PathwayBrowser/#/R-DME-110506 Activated DTOR phosphorylates DS6K TAS Drosophila melanogaster 30616 R-DME-110518 https://reactome.org/PathwayBrowser/#/R-DME-110518 Activated DTOR also phosphorylates D4EBP TAS Drosophila melanogaster 30616 R-DME-111751 https://reactome.org/PathwayBrowser/#/R-DME-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 30616 R-DME-111804 https://reactome.org/PathwayBrowser/#/R-DME-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 30616 R-DME-111915 https://reactome.org/PathwayBrowser/#/R-DME-111915 CAMK4 autophosphorylates IEA Drosophila melanogaster 30616 R-DME-111930 https://reactome.org/PathwayBrowser/#/R-DME-111930 Adenylate cyclase produces cAMP IEA Drosophila melanogaster 30616 R-DME-111970 https://reactome.org/PathwayBrowser/#/R-DME-111970 PKC phosphorylates GRK2 IEA Drosophila melanogaster 30616 R-DME-112342 https://reactome.org/PathwayBrowser/#/R-DME-112342 Inactivation of MAP2K1 by CDK1 IEA Drosophila melanogaster 30616 R-DME-114252 https://reactome.org/PathwayBrowser/#/R-DME-114252 Cleavage of Procaspase-3 by the apoptosome IEA Drosophila melanogaster 30616 R-DME-114254 https://reactome.org/PathwayBrowser/#/R-DME-114254 CYCS binds to APAF1 IEA Drosophila melanogaster 30616 R-DME-114256 https://reactome.org/PathwayBrowser/#/R-DME-114256 CYCS:APAF1 binds procaspase-9 IEA Drosophila melanogaster 30616 R-DME-114683 https://reactome.org/PathwayBrowser/#/R-DME-114683 Phosphorylation of Platelet Sec-1 IEA Drosophila melanogaster 30616 R-DME-114684 https://reactome.org/PathwayBrowser/#/R-DME-114684 Phosphorylation of Syntaxin-4 IEA Drosophila melanogaster 30616 R-DME-1168638 https://reactome.org/PathwayBrowser/#/R-DME-1168638 Activated IKK phosphorylates I-kappaB IEA Drosophila melanogaster 30616 R-DME-1169397 https://reactome.org/PathwayBrowser/#/R-DME-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Drosophila melanogaster 30616 R-DME-1169398 https://reactome.org/PathwayBrowser/#/R-DME-1169398 ISGylation of host protein filamin B IEA Drosophila melanogaster 30616 R-DME-1169402 https://reactome.org/PathwayBrowser/#/R-DME-1169402 ISGylation of E2 conjugating enzymes IEA Drosophila melanogaster 30616 R-DME-1169405 https://reactome.org/PathwayBrowser/#/R-DME-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Drosophila melanogaster 30616 R-DME-1169406 https://reactome.org/PathwayBrowser/#/R-DME-1169406 ISGylation of host proteins IEA Drosophila melanogaster 30616 R-DME-1181149 https://reactome.org/PathwayBrowser/#/R-DME-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Drosophila melanogaster 30616 R-DME-1226094 https://reactome.org/PathwayBrowser/#/R-DME-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Drosophila melanogaster 30616 R-DME-1226095 https://reactome.org/PathwayBrowser/#/R-DME-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Drosophila melanogaster 30616 R-DME-1247935 https://reactome.org/PathwayBrowser/#/R-DME-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Drosophila melanogaster 30616 R-DME-1247960 https://reactome.org/PathwayBrowser/#/R-DME-1247960 Activation of p38 MAPK IEA Drosophila melanogaster 30616 R-DME-1250195 https://reactome.org/PathwayBrowser/#/R-DME-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Drosophila melanogaster 30616 R-DME-1250315 https://reactome.org/PathwayBrowser/#/R-DME-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Drosophila melanogaster 30616 R-DME-1250348 https://reactome.org/PathwayBrowser/#/R-DME-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Drosophila melanogaster 30616 R-DME-1250370 https://reactome.org/PathwayBrowser/#/R-DME-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Drosophila melanogaster 30616 R-DME-1250462 https://reactome.org/PathwayBrowser/#/R-DME-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Drosophila melanogaster 30616 R-DME-1295609 https://reactome.org/PathwayBrowser/#/R-DME-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Drosophila melanogaster 30616 R-DME-1296024 https://reactome.org/PathwayBrowser/#/R-DME-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Drosophila melanogaster 30616 R-DME-1306957 https://reactome.org/PathwayBrowser/#/R-DME-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Drosophila melanogaster 30616 R-DME-1306979 https://reactome.org/PathwayBrowser/#/R-DME-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Drosophila melanogaster 30616 R-DME-1307963 https://reactome.org/PathwayBrowser/#/R-DME-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Drosophila melanogaster 30616 R-DME-1358791 https://reactome.org/PathwayBrowser/#/R-DME-1358791 Phosphorylation of USP8 by P-AKT IEA Drosophila melanogaster 30616 R-DME-1362270 https://reactome.org/PathwayBrowser/#/R-DME-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Drosophila melanogaster 30616 R-DME-1369065 https://reactome.org/PathwayBrowser/#/R-DME-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Drosophila melanogaster 30616 R-DME-1433418 https://reactome.org/PathwayBrowser/#/R-DME-1433418 Phosphorylation of JAK2 IEA Drosophila melanogaster 30616 R-DME-1433506 https://reactome.org/PathwayBrowser/#/R-DME-1433506 Phosphorylation of APS IEA Drosophila melanogaster 30616 R-DME-1433508 https://reactome.org/PathwayBrowser/#/R-DME-1433508 PKC alpha interacts with and phosphorylates KIT IEA Drosophila melanogaster 30616 R-DME-1454916 https://reactome.org/PathwayBrowser/#/R-DME-1454916 The ABCC family mediates organic anion transport IEA Drosophila melanogaster 30616 R-DME-1454928 https://reactome.org/PathwayBrowser/#/R-DME-1454928 ABCG4 may mediate cholesterol efflux IEA Drosophila melanogaster 30616 R-DME-1467466 https://reactome.org/PathwayBrowser/#/R-DME-1467466 ABCA4 mediates atRAL transport IEA Drosophila melanogaster 30616 R-DME-1470009 https://reactome.org/PathwayBrowser/#/R-DME-1470009 Phosphorylation of STATs IEA Drosophila melanogaster 30616 R-DME-1475422 https://reactome.org/PathwayBrowser/#/R-DME-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Drosophila melanogaster 30616 R-DME-1483004 https://reactome.org/PathwayBrowser/#/R-DME-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Drosophila melanogaster 30616 R-DME-1483222 https://reactome.org/PathwayBrowser/#/R-DME-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Drosophila melanogaster 30616 R-DME-1497853 https://reactome.org/PathwayBrowser/#/R-DME-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Drosophila melanogaster 30616 R-DME-1524186 https://reactome.org/PathwayBrowser/#/R-DME-1524186 Phosphorylation of PLCgamma by PDGFR IEA Drosophila melanogaster 30616 R-DME-1549526 https://reactome.org/PathwayBrowser/#/R-DME-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Drosophila melanogaster 30616 R-DME-156673 https://reactome.org/PathwayBrowser/#/R-DME-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Drosophila melanogaster 30616 R-DME-156678 https://reactome.org/PathwayBrowser/#/R-DME-156678 Activation of Cdc25C IEA Drosophila melanogaster 30616 R-DME-156682 https://reactome.org/PathwayBrowser/#/R-DME-156682 PLK1 phosphorylates NUDC IEA Drosophila melanogaster 30616 R-DME-156699 https://reactome.org/PathwayBrowser/#/R-DME-156699 Inactivation of Wee1 kinase IEA Drosophila melanogaster 30616 R-DME-156723 https://reactome.org/PathwayBrowser/#/R-DME-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Drosophila melanogaster 30616 R-DME-159101 https://reactome.org/PathwayBrowser/#/R-DME-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Drosophila melanogaster 30616 R-DME-159425 https://reactome.org/PathwayBrowser/#/R-DME-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 30616 R-DME-162657 https://reactome.org/PathwayBrowser/#/R-DME-162657 Inactivation of Myt1 kinase IEA Drosophila melanogaster 30616 R-DME-163010 https://reactome.org/PathwayBrowser/#/R-DME-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Drosophila melanogaster 30616 R-DME-163215 https://reactome.org/PathwayBrowser/#/R-DME-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Drosophila melanogaster 30616 R-DME-1632857 https://reactome.org/PathwayBrowser/#/R-DME-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Drosophila melanogaster 30616 R-DME-1638845 https://reactome.org/PathwayBrowser/#/R-DME-1638845 CERK phosphorylates CERA to form C1P IEA Drosophila melanogaster 30616 R-DME-164696 https://reactome.org/PathwayBrowser/#/R-DME-164696 Chico is phosphorylated TAS Drosophila melanogaster 30616 R-DME-164832 https://reactome.org/PathwayBrowser/#/R-DME-164832 ATPase synthesizes ATP IEA Drosophila melanogaster 30616 R-DME-164834 https://reactome.org/PathwayBrowser/#/R-DME-164834 Enzyme-bound ATP is released IEA Drosophila melanogaster 30616 R-DME-165162 https://reactome.org/PathwayBrowser/#/R-DME-165162 Phosphorylation of TSC2 by PKB IEA Drosophila melanogaster 30616 R-DME-165182 https://reactome.org/PathwayBrowser/#/R-DME-165182 Phosphorylation of complexed TSC2 by PKB IEA Drosophila melanogaster 30616 R-DME-165692 https://reactome.org/PathwayBrowser/#/R-DME-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Drosophila melanogaster 30616 R-DME-165718 https://reactome.org/PathwayBrowser/#/R-DME-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Drosophila melanogaster 30616 R-DME-165726 https://reactome.org/PathwayBrowser/#/R-DME-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Drosophila melanogaster 30616 R-DME-165766 https://reactome.org/PathwayBrowser/#/R-DME-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Drosophila melanogaster 30616 R-DME-1675773 https://reactome.org/PathwayBrowser/#/R-DME-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Drosophila melanogaster 30616 R-DME-1675776 https://reactome.org/PathwayBrowser/#/R-DME-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Drosophila melanogaster 30616 R-DME-1675780 https://reactome.org/PathwayBrowser/#/R-DME-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Drosophila melanogaster 30616 R-DME-1675810 https://reactome.org/PathwayBrowser/#/R-DME-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Drosophila melanogaster 30616 R-DME-1675813 https://reactome.org/PathwayBrowser/#/R-DME-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Drosophila melanogaster 30616 R-DME-1675883 https://reactome.org/PathwayBrowser/#/R-DME-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Drosophila melanogaster 30616 R-DME-1675928 https://reactome.org/PathwayBrowser/#/R-DME-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Drosophila melanogaster 30616 R-DME-1675939 https://reactome.org/PathwayBrowser/#/R-DME-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Drosophila melanogaster 30616 R-DME-1675961 https://reactome.org/PathwayBrowser/#/R-DME-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Drosophila melanogaster 30616 R-DME-1675974 https://reactome.org/PathwayBrowser/#/R-DME-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Drosophila melanogaster 30616 R-DME-1676024 https://reactome.org/PathwayBrowser/#/R-DME-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Drosophila melanogaster 30616 R-DME-1676048 https://reactome.org/PathwayBrowser/#/R-DME-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Drosophila melanogaster 30616 R-DME-1676082 https://reactome.org/PathwayBrowser/#/R-DME-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Drosophila melanogaster 30616 R-DME-1676109 https://reactome.org/PathwayBrowser/#/R-DME-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Drosophila melanogaster 30616 R-DME-1676134 https://reactome.org/PathwayBrowser/#/R-DME-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Drosophila melanogaster 30616 R-DME-1676145 https://reactome.org/PathwayBrowser/#/R-DME-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Drosophila melanogaster 30616 R-DME-1676185 https://reactome.org/PathwayBrowser/#/R-DME-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Drosophila melanogaster 30616 R-DME-1676206 https://reactome.org/PathwayBrowser/#/R-DME-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Drosophila melanogaster 30616 R-DME-168053 https://reactome.org/PathwayBrowser/#/R-DME-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Drosophila melanogaster 30616 R-DME-168136 https://reactome.org/PathwayBrowser/#/R-DME-168136 Activated JNKs phosphorylate c-JUN IEA Drosophila melanogaster 30616 R-DME-168140 https://reactome.org/PathwayBrowser/#/R-DME-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Drosophila melanogaster 30616 R-DME-168162 https://reactome.org/PathwayBrowser/#/R-DME-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Drosophila melanogaster 30616 R-DME-169827 https://reactome.org/PathwayBrowser/#/R-DME-169827 DPDK1 phosphorylates and activates DS6K TAS Drosophila melanogaster 30616 R-DME-169828 https://reactome.org/PathwayBrowser/#/R-DME-169828 Activated DAkt1 phosphorylates TSC2 which inhibits the TSC1/2 complex TAS Drosophila melanogaster 30616 R-DME-170026 https://reactome.org/PathwayBrowser/#/R-DME-170026 Protons are translocated from the intermembrane space to the matrix IEA Drosophila melanogaster 30616 R-DME-170055 https://reactome.org/PathwayBrowser/#/R-DME-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Drosophila melanogaster 30616 R-DME-170070 https://reactome.org/PathwayBrowser/#/R-DME-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Drosophila melanogaster 30616 R-DME-170076 https://reactome.org/PathwayBrowser/#/R-DME-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Drosophila melanogaster 30616 R-DME-170087 https://reactome.org/PathwayBrowser/#/R-DME-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Drosophila melanogaster 30616 R-DME-170126 https://reactome.org/PathwayBrowser/#/R-DME-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Drosophila melanogaster 30616 R-DME-170676 https://reactome.org/PathwayBrowser/#/R-DME-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Drosophila melanogaster 30616 R-DME-170843 https://reactome.org/PathwayBrowser/#/R-DME-170843 TGFBR2 phosphorylates TGFBR1 IEA Drosophila melanogaster 30616 R-DME-170868 https://reactome.org/PathwayBrowser/#/R-DME-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Drosophila melanogaster 30616 R-DME-174079 https://reactome.org/PathwayBrowser/#/R-DME-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Drosophila melanogaster 30616 R-DME-174122 https://reactome.org/PathwayBrowser/#/R-DME-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Drosophila melanogaster 30616 R-DME-174164 https://reactome.org/PathwayBrowser/#/R-DME-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Drosophila melanogaster 30616 R-DME-174174 https://reactome.org/PathwayBrowser/#/R-DME-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Drosophila melanogaster 30616 R-DME-174251 https://reactome.org/PathwayBrowser/#/R-DME-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Drosophila melanogaster 30616 R-DME-174367 https://reactome.org/PathwayBrowser/#/R-DME-174367 GCL ligates L-Glu to L-Cys IEA Drosophila melanogaster 30616 R-DME-174389 https://reactome.org/PathwayBrowser/#/R-DME-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Drosophila melanogaster 30616 R-DME-174392 https://reactome.org/PathwayBrowser/#/R-DME-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Drosophila melanogaster 30616 R-DME-174394 https://reactome.org/PathwayBrowser/#/R-DME-174394 GSS:Mg2+ dimer synthesizes GSH IEA Drosophila melanogaster 30616 R-DME-176116 https://reactome.org/PathwayBrowser/#/R-DME-176116 Recruitment and activation of Chk1 IEA Drosophila melanogaster 30616 R-DME-176298 https://reactome.org/PathwayBrowser/#/R-DME-176298 Activation of claspin IEA Drosophila melanogaster 30616 R-DME-177284 https://reactome.org/PathwayBrowser/#/R-DME-177284 PKA phosphorylates PDE4B IEA Drosophila melanogaster 30616 R-DME-177930 https://reactome.org/PathwayBrowser/#/R-DME-177930 GAB1 phosphorylation by EGFR kinase IEA Drosophila melanogaster 30616 R-DME-177933 https://reactome.org/PathwayBrowser/#/R-DME-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Drosophila melanogaster 30616 R-DME-177934 https://reactome.org/PathwayBrowser/#/R-DME-177934 EGFR autophosphorylation IEA Drosophila melanogaster 30616 R-DME-177937 https://reactome.org/PathwayBrowser/#/R-DME-177937 Phosphorylation of EGFR by SRC kinase IEA Drosophila melanogaster 30616 R-DME-177939 https://reactome.org/PathwayBrowser/#/R-DME-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Drosophila melanogaster 30616 R-DME-182969 https://reactome.org/PathwayBrowser/#/R-DME-182969 Phosphorylation of CBL (EGFR:CBL) IEA Drosophila melanogaster 30616 R-DME-183058 https://reactome.org/PathwayBrowser/#/R-DME-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Drosophila melanogaster 30616 R-DME-1855153 https://reactome.org/PathwayBrowser/#/R-DME-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Drosophila melanogaster 30616 R-DME-1855157 https://reactome.org/PathwayBrowser/#/R-DME-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 30616 R-DME-1855158 https://reactome.org/PathwayBrowser/#/R-DME-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 30616 R-DME-1855181 https://reactome.org/PathwayBrowser/#/R-DME-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 30616 R-DME-1855182 https://reactome.org/PathwayBrowser/#/R-DME-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Drosophila melanogaster 30616 R-DME-1855185 https://reactome.org/PathwayBrowser/#/R-DME-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 30616 R-DME-1855193 https://reactome.org/PathwayBrowser/#/R-DME-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 30616 R-DME-1855194 https://reactome.org/PathwayBrowser/#/R-DME-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 30616 R-DME-1855206 https://reactome.org/PathwayBrowser/#/R-DME-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 30616 R-DME-1855207 https://reactome.org/PathwayBrowser/#/R-DME-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 30616 R-DME-1855216 https://reactome.org/PathwayBrowser/#/R-DME-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Drosophila melanogaster 30616 R-DME-1855223 https://reactome.org/PathwayBrowser/#/R-DME-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 30616 R-DME-1855224 https://reactome.org/PathwayBrowser/#/R-DME-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 30616 R-DME-1855227 https://reactome.org/PathwayBrowser/#/R-DME-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 30616 R-DME-1855228 https://reactome.org/PathwayBrowser/#/R-DME-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 30616 R-DME-1855230 https://reactome.org/PathwayBrowser/#/R-DME-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 30616 R-DME-1855233 https://reactome.org/PathwayBrowser/#/R-DME-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Drosophila melanogaster 30616 R-DME-186786 https://reactome.org/PathwayBrowser/#/R-DME-186786 Autophosphorylation of PDGF beta receptors IEA Drosophila melanogaster 30616 R-DME-186800 https://reactome.org/PathwayBrowser/#/R-DME-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-187520 https://reactome.org/PathwayBrowser/#/R-DME-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Drosophila melanogaster 30616 R-DME-187688 https://reactome.org/PathwayBrowser/#/R-DME-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Drosophila melanogaster 30616 R-DME-187916 https://reactome.org/PathwayBrowser/#/R-DME-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Drosophila melanogaster 30616 R-DME-187948 https://reactome.org/PathwayBrowser/#/R-DME-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Drosophila melanogaster 30616 R-DME-187949 https://reactome.org/PathwayBrowser/#/R-DME-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Drosophila melanogaster 30616 R-DME-187959 https://reactome.org/PathwayBrowser/#/R-DME-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Drosophila melanogaster 30616 R-DME-188350 https://reactome.org/PathwayBrowser/#/R-DME-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Drosophila melanogaster 30616 R-DME-190326 https://reactome.org/PathwayBrowser/#/R-DME-190326 Autocatalytic phosphorylation of FGFR4 IEA Drosophila melanogaster 30616 R-DME-190385 https://reactome.org/PathwayBrowser/#/R-DME-190385 Autocatalytic phosphorylation of FGFR3b IEA Drosophila melanogaster 30616 R-DME-190388 https://reactome.org/PathwayBrowser/#/R-DME-190388 Autocatalytic phosphorylation of FGFR3c IEA Drosophila melanogaster 30616 R-DME-190408 https://reactome.org/PathwayBrowser/#/R-DME-190408 Autocatalytic phosphorylation of FGFR2b IEA Drosophila melanogaster 30616 R-DME-190413 https://reactome.org/PathwayBrowser/#/R-DME-190413 Autocatalytic phosphorylation of FGFR2c IEA Drosophila melanogaster 30616 R-DME-190427 https://reactome.org/PathwayBrowser/#/R-DME-190427 Autocatalytic phosphorylation of FGFR1b IEA Drosophila melanogaster 30616 R-DME-190429 https://reactome.org/PathwayBrowser/#/R-DME-190429 Autocatalytic phosphorylation of FGFR1c IEA Drosophila melanogaster 30616 R-DME-191062 https://reactome.org/PathwayBrowser/#/R-DME-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Drosophila melanogaster 30616 R-DME-191380 https://reactome.org/PathwayBrowser/#/R-DME-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Drosophila melanogaster 30616 R-DME-191414 https://reactome.org/PathwayBrowser/#/R-DME-191414 MVD decarboxylates MVA5PP to IPPP IEA Drosophila melanogaster 30616 R-DME-191422 https://reactome.org/PathwayBrowser/#/R-DME-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Drosophila melanogaster 30616 R-DME-192137 https://reactome.org/PathwayBrowser/#/R-DME-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 30616 R-DME-193401 https://reactome.org/PathwayBrowser/#/R-DME-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 30616 R-DME-193407 https://reactome.org/PathwayBrowser/#/R-DME-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 30616 R-DME-193424 https://reactome.org/PathwayBrowser/#/R-DME-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 30616 R-DME-193711 https://reactome.org/PathwayBrowser/#/R-DME-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 30616 R-DME-193727 https://reactome.org/PathwayBrowser/#/R-DME-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 30616 R-DME-193743 https://reactome.org/PathwayBrowser/#/R-DME-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 30616 R-DME-193766 https://reactome.org/PathwayBrowser/#/R-DME-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 30616 R-DME-194153 https://reactome.org/PathwayBrowser/#/R-DME-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Drosophila melanogaster 30616 R-DME-195275 https://reactome.org/PathwayBrowser/#/R-DME-195275 Phosphorylation of APC component of the destruction complex IEA Drosophila melanogaster 30616 R-DME-195283 https://reactome.org/PathwayBrowser/#/R-DME-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Drosophila melanogaster 30616 R-DME-195287 https://reactome.org/PathwayBrowser/#/R-DME-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Drosophila melanogaster 30616 R-DME-195300 https://reactome.org/PathwayBrowser/#/R-DME-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Drosophila melanogaster 30616 R-DME-195318 https://reactome.org/PathwayBrowser/#/R-DME-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Drosophila melanogaster 30616 R-DME-1963581 https://reactome.org/PathwayBrowser/#/R-DME-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Drosophila melanogaster 30616 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 30616 R-DME-1963586 https://reactome.org/PathwayBrowser/#/R-DME-1963586 SRC family kinases phosphorylate ERBB2 IEA Drosophila melanogaster 30616 R-DME-196753 https://reactome.org/PathwayBrowser/#/R-DME-196753 2xPPCS ligates PPanK with Cys IEA Drosophila melanogaster 30616 R-DME-196761 https://reactome.org/PathwayBrowser/#/R-DME-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Drosophila melanogaster 30616 R-DME-196857 https://reactome.org/PathwayBrowser/#/R-DME-196857 PANK2 phosphorylates PanK IEA Drosophila melanogaster 30616 R-DME-196929 https://reactome.org/PathwayBrowser/#/R-DME-196929 FLAD1 phosphorylates FMN IEA Drosophila melanogaster 30616 R-DME-196964 https://reactome.org/PathwayBrowser/#/R-DME-196964 RFK:Mg2+ phosphorylates RIB IEA Drosophila melanogaster 30616 R-DME-197198 https://reactome.org/PathwayBrowser/#/R-DME-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 30616 R-DME-197235 https://reactome.org/PathwayBrowser/#/R-DME-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 30616 R-DME-197271 https://reactome.org/PathwayBrowser/#/R-DME-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Drosophila melanogaster 30616 R-DME-197958 https://reactome.org/PathwayBrowser/#/R-DME-197958 FPGS-2 transforms THF to THFPG IEA Drosophila melanogaster 30616 R-DME-198266 https://reactome.org/PathwayBrowser/#/R-DME-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Drosophila melanogaster 30616 R-DME-198314 https://reactome.org/PathwayBrowser/#/R-DME-198314 DAG stimulates protein kinase C-delta IEA Drosophila melanogaster 30616 R-DME-198609 https://reactome.org/PathwayBrowser/#/R-DME-198609 AKT phosphorylates TSC2, inhibiting it IEA Drosophila melanogaster 30616 R-DME-198611 https://reactome.org/PathwayBrowser/#/R-DME-198611 AKT phosphorylates IKKalpha IEA Drosophila melanogaster 30616 R-DME-198613 https://reactome.org/PathwayBrowser/#/R-DME-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Drosophila melanogaster 30616 R-DME-198621 https://reactome.org/PathwayBrowser/#/R-DME-198621 AKT phosphorylates caspase-9 IEA Drosophila melanogaster 30616 R-DME-198640 https://reactome.org/PathwayBrowser/#/R-DME-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Drosophila melanogaster 30616 R-DME-198669 https://reactome.org/PathwayBrowser/#/R-DME-198669 p38MAPK phosphorylates MSK1 IEA Drosophila melanogaster 30616 R-DME-198746 https://reactome.org/PathwayBrowser/#/R-DME-198746 ERK1/2/5 activate RSK1/2/3 IEA Drosophila melanogaster 30616 R-DME-198756 https://reactome.org/PathwayBrowser/#/R-DME-198756 ERK1/2 phosphorylates MSK1 IEA Drosophila melanogaster 30616 R-DME-199203 https://reactome.org/PathwayBrowser/#/R-DME-199203 PANK1/3 phosphorylate PanK IEA Drosophila melanogaster 30616 R-DME-199298 https://reactome.org/PathwayBrowser/#/R-DME-199298 AKT phosphorylates CREB1 IEA Drosophila melanogaster 30616 R-DME-199299 https://reactome.org/PathwayBrowser/#/R-DME-199299 AKT phosphorylates FOXO transcription factors IEA Drosophila melanogaster 30616 R-DME-199839 https://reactome.org/PathwayBrowser/#/R-DME-199839 AKT can phosphorylate RSK IEA Drosophila melanogaster 30616 R-DME-199863 https://reactome.org/PathwayBrowser/#/R-DME-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Drosophila melanogaster 30616 R-DME-199895 https://reactome.org/PathwayBrowser/#/R-DME-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Drosophila melanogaster 30616 R-DME-199910 https://reactome.org/PathwayBrowser/#/R-DME-199910 MSK1 activates ATF1 IEA Drosophila melanogaster 30616 R-DME-199917 https://reactome.org/PathwayBrowser/#/R-DME-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Drosophila melanogaster 30616 R-DME-199935 https://reactome.org/PathwayBrowser/#/R-DME-199935 MSK1 activates CREB IEA Drosophila melanogaster 30616 R-DME-200143 https://reactome.org/PathwayBrowser/#/R-DME-200143 AKT phosphorylates AKT1S1 (PRAS40) IEA Drosophila melanogaster 30616 R-DME-200423 https://reactome.org/PathwayBrowser/#/R-DME-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Drosophila melanogaster 30616 R-DME-200474 https://reactome.org/PathwayBrowser/#/R-DME-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 30616 R-DME-200512 https://reactome.org/PathwayBrowser/#/R-DME-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 30616 R-DME-200555 https://reactome.org/PathwayBrowser/#/R-DME-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Drosophila melanogaster 30616 R-DME-200681 https://reactome.org/PathwayBrowser/#/R-DME-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Drosophila melanogaster 30616 R-DME-200682 https://reactome.org/PathwayBrowser/#/R-DME-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Drosophila melanogaster 30616 R-DME-200711 https://reactome.org/PathwayBrowser/#/R-DME-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Drosophila melanogaster 30616 R-DME-201035 https://reactome.org/PathwayBrowser/#/R-DME-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Drosophila melanogaster 30616 R-DME-201443 https://reactome.org/PathwayBrowser/#/R-DME-201443 Type II receptor phosphorylates type I receptor IEA Drosophila melanogaster 30616 R-DME-201476 https://reactome.org/PathwayBrowser/#/R-DME-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Drosophila melanogaster 30616 R-DME-201510 https://reactome.org/PathwayBrowser/#/R-DME-201510 PI3K synthesizes PIP3 downstream of ALK IEA Drosophila melanogaster 30616 R-DME-201677 https://reactome.org/PathwayBrowser/#/R-DME-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Drosophila melanogaster 30616 R-DME-201717 https://reactome.org/PathwayBrowser/#/R-DME-201717 CSNK2-mediated phosphorylation of DVL IEA Drosophila melanogaster 30616 R-DME-202111 https://reactome.org/PathwayBrowser/#/R-DME-202111 AKT1 phosphorylates eNOS IEA Drosophila melanogaster 30616 R-DME-202222 https://reactome.org/PathwayBrowser/#/R-DME-202222 Phosphorylation of PKC theta IEA Drosophila melanogaster 30616 R-DME-202248 https://reactome.org/PathwayBrowser/#/R-DME-202248 Phosphorylation of PLC-gamma1 IEA Drosophila melanogaster 30616 R-DME-202541 https://reactome.org/PathwayBrowser/#/R-DME-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Drosophila melanogaster 30616 R-DME-2028284 https://reactome.org/PathwayBrowser/#/R-DME-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Drosophila melanogaster 30616 R-DME-2028555 https://reactome.org/PathwayBrowser/#/R-DME-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Drosophila melanogaster 30616 R-DME-2028589 https://reactome.org/PathwayBrowser/#/R-DME-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Drosophila melanogaster 30616 R-DME-2028591 https://reactome.org/PathwayBrowser/#/R-DME-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Drosophila melanogaster 30616 R-DME-2028629 https://reactome.org/PathwayBrowser/#/R-DME-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Drosophila melanogaster 30616 R-DME-2028635 https://reactome.org/PathwayBrowser/#/R-DME-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Drosophila melanogaster 30616 R-DME-2028670 https://reactome.org/PathwayBrowser/#/R-DME-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Drosophila melanogaster 30616 R-DME-2028673 https://reactome.org/PathwayBrowser/#/R-DME-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Drosophila melanogaster 30616 R-DME-2028675 https://reactome.org/PathwayBrowser/#/R-DME-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Drosophila melanogaster 30616 R-DME-2028679 https://reactome.org/PathwayBrowser/#/R-DME-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Drosophila melanogaster 30616 R-DME-2029454 https://reactome.org/PathwayBrowser/#/R-DME-2029454 Autophosphorylation of PAK1 IEA Drosophila melanogaster 30616 R-DME-2029460 https://reactome.org/PathwayBrowser/#/R-DME-2029460 PAK1 phosphorylates LIMK1 IEA Drosophila melanogaster 30616 R-DME-2029466 https://reactome.org/PathwayBrowser/#/R-DME-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Drosophila melanogaster 30616 R-DME-2029469 https://reactome.org/PathwayBrowser/#/R-DME-2029469 p-ERK phosphorylates WAVEs and ABI IEA Drosophila melanogaster 30616 R-DME-2029473 https://reactome.org/PathwayBrowser/#/R-DME-2029473 Branching and elongation of mother and daughter filaments IEA Drosophila melanogaster 30616 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 30616 R-DME-2046087 https://reactome.org/PathwayBrowser/#/R-DME-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Drosophila melanogaster 30616 R-DME-2046093 https://reactome.org/PathwayBrowser/#/R-DME-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Drosophila melanogaster 30616 R-DME-205136 https://reactome.org/PathwayBrowser/#/R-DME-205136 GTP-bound RAC contributes to JNK activation IEA Drosophila melanogaster 30616 R-DME-209049 https://reactome.org/PathwayBrowser/#/R-DME-209049 Phosphorylation of AXN and APC by SGG IEA Drosophila melanogaster 30616 R-DME-209057 https://reactome.org/PathwayBrowser/#/R-DME-209057 Activated PLL kinase is autophosphorylated in TL:MYD88:TUB:PLL 'signalling complex' TAS Drosophila melanogaster 30616 R-DME-209082 https://reactome.org/PathwayBrowser/#/R-DME-209082 Further phosphorylation of APC by SGG IEA Drosophila melanogaster 30616 R-DME-209087 https://reactome.org/PathwayBrowser/#/R-DME-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Drosophila melanogaster 30616 R-DME-209107 https://reactome.org/PathwayBrowser/#/R-DME-209107 Further phosphorylation of APC by DCO IEA Drosophila melanogaster 30616 R-DME-209109 https://reactome.org/PathwayBrowser/#/R-DME-209109 Further phosphorylation of ARM by SGG TAS Drosophila melanogaster 30616 R-DME-209118 https://reactome.org/PathwayBrowser/#/R-DME-209118 Membrane localised SGG phosphorylates ARR TAS Drosophila melanogaster 30616 R-DME-209134 https://reactome.org/PathwayBrowser/#/R-DME-209134 Phosphorylation of ARM by CKIalpha TAS Drosophila melanogaster 30616 R-DME-209135 https://reactome.org/PathwayBrowser/#/R-DME-209135 GISH further phosphorylates ARR in the receptor complex IEA Drosophila melanogaster 30616 R-DME-209143 https://reactome.org/PathwayBrowser/#/R-DME-209143 Phosphorylation of AXN and APC by DCO IEA Drosophila melanogaster 30616 R-DME-209160 https://reactome.org/PathwayBrowser/#/R-DME-209160 Phosphorylated HOP phosphorylates DOME TAS Drosophila melanogaster 30616 R-DME-209168 https://reactome.org/PathwayBrowser/#/R-DME-209168 Phosphorylation of SMO by CKIalpha TAS Drosophila melanogaster 30616 R-DME-209172 https://reactome.org/PathwayBrowser/#/R-DME-209172 Phosphorylation of CI by SGG TAS Drosophila melanogaster 30616 R-DME-209187 https://reactome.org/PathwayBrowser/#/R-DME-209187 Further phosphorylation of CI by CKIalphaepsilon TAS Drosophila melanogaster 30616 R-DME-209196 https://reactome.org/PathwayBrowser/#/R-DME-209196 Phosphorylation of CI by PKA-C1 TAS Drosophila melanogaster 30616 R-DME-209199 https://reactome.org/PathwayBrowser/#/R-DME-209199 CKA is phosphorylated by phosphorylated BSK kinase TAS Drosophila melanogaster 30616 R-DME-209200 https://reactome.org/PathwayBrowser/#/R-DME-209200 HEP is phosphorylated and activated by Phospho TAK1:TAB2 kinase complex IEA Drosophila melanogaster 30616 R-DME-209210 https://reactome.org/PathwayBrowser/#/R-DME-209210 STAT92E is phosphorylated by phosphorylated HOP TAS Drosophila melanogaster 30616 R-DME-209220 https://reactome.org/PathwayBrowser/#/R-DME-209220 Liberation of CI from SU(FU) repression TAS Drosophila melanogaster 30616 R-DME-209227 https://reactome.org/PathwayBrowser/#/R-DME-209227 Activated Phospho IRD5:KEY dimer phosphorylates REL in the PGN:PGRP-LC oligomer receptor 'signalling complex' TAS Drosophila melanogaster 30616 R-DME-209240 https://reactome.org/PathwayBrowser/#/R-DME-209240 Activated phosphorylated TAK1 kinase phosphorylates and activates IRD5 TAS Drosophila melanogaster 30616 R-DME-209253 https://reactome.org/PathwayBrowser/#/R-DME-209253 Autophosphorylated FU phosphorylates COS TAS Drosophila melanogaster 30616 R-DME-209293 https://reactome.org/PathwayBrowser/#/R-DME-209293 Phosphorylation of CI by CKIalphaepsilon (CKIalpha/DCO) TAS Drosophila melanogaster 30616 R-DME-209298 https://reactome.org/PathwayBrowser/#/R-DME-209298 BSK is phosphorylated and activated by phosphorylated HEP kinase TAS Drosophila melanogaster 30616 R-DME-209320 https://reactome.org/PathwayBrowser/#/R-DME-209320 Activated TAK1 kinase is autophosphorylated TAS Drosophila melanogaster 30616 R-DME-209336 https://reactome.org/PathwayBrowser/#/R-DME-209336 Activated HOP is autophosphorylated and/or transphosphorylated TAS Drosophila melanogaster 30616 R-DME-209341 https://reactome.org/PathwayBrowser/#/R-DME-209341 Phosphorylation of SMO by PKA-C1 TAS Drosophila melanogaster 30616 R-DME-209381 https://reactome.org/PathwayBrowser/#/R-DME-209381 AP-1 transcription factor, JRA:KAY, is phosphorylated by phosphorylated BSK kinase TAS Drosophila melanogaster 30616 R-DME-211164 https://reactome.org/PathwayBrowser/#/R-DME-211164 AKT phosphorylates FOXO1A IEA Drosophila melanogaster 30616 R-DME-212710 https://reactome.org/PathwayBrowser/#/R-DME-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Drosophila melanogaster 30616 R-DME-2130194 https://reactome.org/PathwayBrowser/#/R-DME-2130194 ABL phosphorylates WAVEs IEA Drosophila melanogaster 30616 R-DME-214398 https://reactome.org/PathwayBrowser/#/R-DME-214398 Activated Phospho IRD5:KEY dimer phosphorylates REL in the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' TAS Drosophila melanogaster 30616 R-DME-214845 https://reactome.org/PathwayBrowser/#/R-DME-214845 CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' TAS Drosophila melanogaster 30616 R-DME-214859 https://reactome.org/PathwayBrowser/#/R-DME-214859 Activated PLL kinase is autophosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' TAS Drosophila melanogaster 30616 R-DME-214860 https://reactome.org/PathwayBrowser/#/R-DME-214860 CACT and DL/DIF dimer are phosphorylated in TL:MYD88:TUB:PLL 'signalling complex' TAS Drosophila melanogaster 30616 R-DME-2168079 https://reactome.org/PathwayBrowser/#/R-DME-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Drosophila melanogaster 30616 R-DME-2176475 https://reactome.org/PathwayBrowser/#/R-DME-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Drosophila melanogaster 30616 R-DME-2197690 https://reactome.org/PathwayBrowser/#/R-DME-2197690 Detachment of WASP/WAVE IEA Drosophila melanogaster 30616 R-DME-2214351 https://reactome.org/PathwayBrowser/#/R-DME-2214351 PLK1 phosphorylates GORASP1 IEA Drosophila melanogaster 30616 R-DME-2316434 https://reactome.org/PathwayBrowser/#/R-DME-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-2422927 https://reactome.org/PathwayBrowser/#/R-DME-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Drosophila melanogaster 30616 R-DME-2424487 https://reactome.org/PathwayBrowser/#/R-DME-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Drosophila melanogaster 30616 R-DME-2430535 https://reactome.org/PathwayBrowser/#/R-DME-2430535 MASTL phosphorylates ENSA IEA Drosophila melanogaster 30616 R-DME-2466068 https://reactome.org/PathwayBrowser/#/R-DME-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Drosophila melanogaster 30616 R-DME-2468293 https://reactome.org/PathwayBrowser/#/R-DME-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Drosophila melanogaster 30616 R-DME-2529020 https://reactome.org/PathwayBrowser/#/R-DME-2529020 CK2 phosphorylates condensin I subunits IEA Drosophila melanogaster 30616 R-DME-2562526 https://reactome.org/PathwayBrowser/#/R-DME-2562526 PLK1 phosphorylates OPTN IEA Drosophila melanogaster 30616 R-DME-265682 https://reactome.org/PathwayBrowser/#/R-DME-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Drosophila melanogaster 30616 R-DME-265783 https://reactome.org/PathwayBrowser/#/R-DME-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Drosophila melanogaster 30616 R-DME-266082 https://reactome.org/PathwayBrowser/#/R-DME-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Drosophila melanogaster 30616 R-DME-2730835 https://reactome.org/PathwayBrowser/#/R-DME-2730835 Autophosphorylation of PKC-theta IEA Drosophila melanogaster 30616 R-DME-2730841 https://reactome.org/PathwayBrowser/#/R-DME-2730841 Phosphorylation and activation of VAV IEA Drosophila melanogaster 30616 R-DME-2730856 https://reactome.org/PathwayBrowser/#/R-DME-2730856 Autophosphorylation of PAK IEA Drosophila melanogaster 30616 R-DME-2730858 https://reactome.org/PathwayBrowser/#/R-DME-2730858 Autophosphorylation of BTK/ITK IEA Drosophila melanogaster 30616 R-DME-2730862 https://reactome.org/PathwayBrowser/#/R-DME-2730862 Autophosphorylation of LYN kinase IEA Drosophila melanogaster 30616 R-DME-2730870 https://reactome.org/PathwayBrowser/#/R-DME-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Drosophila melanogaster 30616 R-DME-2990882 https://reactome.org/PathwayBrowser/#/R-DME-2990882 CDK1 phosphorylates NUP98 IEA Drosophila melanogaster 30616 R-DME-2993799 https://reactome.org/PathwayBrowser/#/R-DME-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Drosophila melanogaster 30616 R-DME-2993802 https://reactome.org/PathwayBrowser/#/R-DME-2993802 HLCS biotinylates PC:Mn2+ IEA Drosophila melanogaster 30616 R-DME-2993814 https://reactome.org/PathwayBrowser/#/R-DME-2993814 HLCS biotinylates ACACA:Mn2+ IEA Drosophila melanogaster 30616 R-DME-3000327 https://reactome.org/PathwayBrowser/#/R-DME-3000327 PLK1 phosphorylates BORA IEA Drosophila melanogaster 30616 R-DME-3095901 https://reactome.org/PathwayBrowser/#/R-DME-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Drosophila melanogaster 30616 R-DME-3132737 https://reactome.org/PathwayBrowser/#/R-DME-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Drosophila melanogaster 30616 R-DME-3228469 https://reactome.org/PathwayBrowser/#/R-DME-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Drosophila melanogaster 30616 R-DME-3229102 https://reactome.org/PathwayBrowser/#/R-DME-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Drosophila melanogaster 30616 R-DME-3249371 https://reactome.org/PathwayBrowser/#/R-DME-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Drosophila melanogaster 30616 R-DME-3249379 https://reactome.org/PathwayBrowser/#/R-DME-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Drosophila melanogaster 30616 R-DME-3249390 https://reactome.org/PathwayBrowser/#/R-DME-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Drosophila melanogaster 30616 R-DME-3371422 https://reactome.org/PathwayBrowser/#/R-DME-3371422 ATP hydrolysis by HSP70 IEA Drosophila melanogaster 30616 R-DME-3371435 https://reactome.org/PathwayBrowser/#/R-DME-3371435 Constitutive phosphorylation by GSK3 IEA Drosophila melanogaster 30616 R-DME-3371531 https://reactome.org/PathwayBrowser/#/R-DME-3371531 Constitutive phosphorylation by pERK1/2 IEA Drosophila melanogaster 30616 R-DME-3371590 https://reactome.org/PathwayBrowser/#/R-DME-3371590 HSP70 binds to HSP40:nascent protein IEA Drosophila melanogaster 30616 R-DME-350362 https://reactome.org/PathwayBrowser/#/R-DME-350362 ROK phosphorylates MBS TAS Drosophila melanogaster 30616 R-DME-350444 https://reactome.org/PathwayBrowser/#/R-DME-350444 ROK phosphorylates SQH TAS Drosophila melanogaster 30616 R-DME-373747 https://reactome.org/PathwayBrowser/#/R-DME-373747 Phosphorylation of nephrin by FYN IEA Drosophila melanogaster 30616 R-DME-373750 https://reactome.org/PathwayBrowser/#/R-DME-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Drosophila melanogaster 30616 R-DME-374664 https://reactome.org/PathwayBrowser/#/R-DME-374664 Phosphorylation and activation of Ezrin IEA Drosophila melanogaster 30616 R-DME-374701 https://reactome.org/PathwayBrowser/#/R-DME-374701 Phosphorylation of DCC by Fyn IEA Drosophila melanogaster 30616 R-DME-3769394 https://reactome.org/PathwayBrowser/#/R-DME-3769394 AKT phosphorylates CBY1 IEA Drosophila melanogaster 30616 R-DME-377186 https://reactome.org/PathwayBrowser/#/R-DME-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Drosophila melanogaster 30616 R-DME-3772435 https://reactome.org/PathwayBrowser/#/R-DME-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Drosophila melanogaster 30616 R-DME-3772436 https://reactome.org/PathwayBrowser/#/R-DME-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Drosophila melanogaster 30616 R-DME-377640 https://reactome.org/PathwayBrowser/#/R-DME-377640 Autophosphorylation of SRC IEA Drosophila melanogaster 30616 R-DME-3788705 https://reactome.org/PathwayBrowser/#/R-DME-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Drosophila melanogaster 30616 R-DME-380278 https://reactome.org/PathwayBrowser/#/R-DME-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Drosophila melanogaster 30616 R-DME-380780 https://reactome.org/PathwayBrowser/#/R-DME-380780 Activation of Src IEA Drosophila melanogaster 30616 R-DME-380927 https://reactome.org/PathwayBrowser/#/R-DME-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Drosophila melanogaster 30616 R-DME-381091 https://reactome.org/PathwayBrowser/#/R-DME-381091 IRE1 dimer autophosphorylates IEA Drosophila melanogaster 30616 R-DME-381111 https://reactome.org/PathwayBrowser/#/R-DME-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Drosophila melanogaster 30616 R-DME-382560 https://reactome.org/PathwayBrowser/#/R-DME-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Drosophila melanogaster 30616 R-DME-382575 https://reactome.org/PathwayBrowser/#/R-DME-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Drosophila melanogaster 30616 R-DME-383190 https://reactome.org/PathwayBrowser/#/R-DME-383190 HCO3- transport through ion channel IEA Drosophila melanogaster 30616 R-DME-3857329 https://reactome.org/PathwayBrowser/#/R-DME-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Drosophila melanogaster 30616 R-DME-389083 https://reactome.org/PathwayBrowser/#/R-DME-389083 Autophosphorylation of PDGF alpha receptors IEA Drosophila melanogaster 30616 R-DME-389086 https://reactome.org/PathwayBrowser/#/R-DME-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Drosophila melanogaster 30616 R-DME-389622 https://reactome.org/PathwayBrowser/#/R-DME-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 30616 R-DME-389632 https://reactome.org/PathwayBrowser/#/R-DME-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 30616 R-DME-389652 https://reactome.org/PathwayBrowser/#/R-DME-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Drosophila melanogaster 30616 R-DME-390025 https://reactome.org/PathwayBrowser/#/R-DME-390025 Phosphorylated WTS autophosphorylates TAS Drosophila melanogaster 30616 R-DME-390035 https://reactome.org/PathwayBrowser/#/R-DME-390035 HPO dimer autophosphorylates TAS Drosophila melanogaster 30616 R-DME-390044 https://reactome.org/PathwayBrowser/#/R-DME-390044 YKI is phosphorylated by and then dissociates from phosphorylated WTS TAS Drosophila melanogaster 30616 R-DME-390112 https://reactome.org/PathwayBrowser/#/R-DME-390112 Phosphorylated HPO dimer phosphorylates WTS TAS Drosophila melanogaster 30616 R-DME-390120 https://reactome.org/PathwayBrowser/#/R-DME-390120 Phosphorylated HPO dimer phosphorylates TH TAS Drosophila melanogaster 30616 R-DME-390145 https://reactome.org/PathwayBrowser/#/R-DME-390145 Phosphorylated HPO dimer phosphorylates SAV TAS Drosophila melanogaster 30616 R-DME-390154 https://reactome.org/PathwayBrowser/#/R-DME-390154 MATS is phosphorylated by HPO dimer and binds to phosphorylated WTS TAS Drosophila melanogaster 30616 R-DME-392300 https://reactome.org/PathwayBrowser/#/R-DME-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-3928578 https://reactome.org/PathwayBrowser/#/R-DME-3928578 EPH receptors autophosphorylate IEA Drosophila melanogaster 30616 R-DME-3928595 https://reactome.org/PathwayBrowser/#/R-DME-3928595 N-WASP binds ARP2/3 and G-actin IEA Drosophila melanogaster 30616 R-DME-3928604 https://reactome.org/PathwayBrowser/#/R-DME-3928604 SFKs phosphorylate VAV2,3 IEA Drosophila melanogaster 30616 R-DME-3928620 https://reactome.org/PathwayBrowser/#/R-DME-3928620 PAK1 autophosphorylates IEA Drosophila melanogaster 30616 R-DME-3928625 https://reactome.org/PathwayBrowser/#/R-DME-3928625 PAKs autophosphorylate IEA Drosophila melanogaster 30616 R-DME-3928627 https://reactome.org/PathwayBrowser/#/R-DME-3928627 EPHB phosphorylates TIAM1 IEA Drosophila melanogaster 30616 R-DME-3928640 https://reactome.org/PathwayBrowser/#/R-DME-3928640 PAKs phosphorylate MLC IEA Drosophila melanogaster 30616 R-DME-3928654 https://reactome.org/PathwayBrowser/#/R-DME-3928654 Clathrin internalises EPH:EFN complexes IEA Drosophila melanogaster 30616 R-DME-399939 https://reactome.org/PathwayBrowser/#/R-DME-399939 Autophosphorylation of PAK IEA Drosophila melanogaster 30616 R-DME-399944 https://reactome.org/PathwayBrowser/#/R-DME-399944 Phosphorylation of CRMPs by Cdk5 IEA Drosophila melanogaster 30616 R-DME-399947 https://reactome.org/PathwayBrowser/#/R-DME-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Drosophila melanogaster 30616 R-DME-399951 https://reactome.org/PathwayBrowser/#/R-DME-399951 Phosphorylation of CRMPs by GSK3beta IEA Drosophila melanogaster 30616 R-DME-399952 https://reactome.org/PathwayBrowser/#/R-DME-399952 Phosphorylation of LIMK-1 by PAK IEA Drosophila melanogaster 30616 R-DME-4086410 https://reactome.org/PathwayBrowser/#/R-DME-4086410 CDK1 phosphorylates BORA IEA Drosophila melanogaster 30616 R-DME-4093332 https://reactome.org/PathwayBrowser/#/R-DME-4093332 p-EPHB phosphorylates SDC2 IEA Drosophila melanogaster 30616 R-DME-416639 https://reactome.org/PathwayBrowser/#/R-DME-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Drosophila melanogaster 30616 R-DME-4167511 https://reactome.org/PathwayBrowser/#/R-DME-4167511 HLCS biotinylates ACACB IEA Drosophila melanogaster 30616 R-DME-416985 https://reactome.org/PathwayBrowser/#/R-DME-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Drosophila melanogaster 30616 R-DME-419644 https://reactome.org/PathwayBrowser/#/R-DME-419644 Transphosphorylation of pLIMK1 IEA Drosophila melanogaster 30616 R-DME-421007 https://reactome.org/PathwayBrowser/#/R-DME-421007 Endocytosis of Ca impermeable AMPA receptors IEA Drosophila melanogaster 30616 R-DME-426240 https://reactome.org/PathwayBrowser/#/R-DME-426240 DAG kinase produces phosphatidic acid from DAG IEA Drosophila melanogaster 30616 R-DME-428273 https://reactome.org/PathwayBrowser/#/R-DME-428273 SPHK1 phosphorylates sphingoid IEA Drosophila melanogaster 30616 R-DME-428888 https://reactome.org/PathwayBrowser/#/R-DME-428888 Phosphorylation of ROBO1 by ABL kinase IEA Drosophila melanogaster 30616 R-DME-428941 https://reactome.org/PathwayBrowser/#/R-DME-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Drosophila melanogaster 30616 R-DME-429157 https://reactome.org/PathwayBrowser/#/R-DME-429157 ABCC4 accumulation of dense granule contents IEA Drosophila melanogaster 30616 R-DME-429441 https://reactome.org/PathwayBrowser/#/R-DME-429441 SYK activation by SRC IEA Drosophila melanogaster 30616 R-DME-429449 https://reactome.org/PathwayBrowser/#/R-DME-429449 Syk activation leads to SLP-76 activation IEA Drosophila melanogaster 30616 R-DME-429698 https://reactome.org/PathwayBrowser/#/R-DME-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Drosophila melanogaster 30616 R-DME-429714 https://reactome.org/PathwayBrowser/#/R-DME-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Drosophila melanogaster 30616 R-DME-430347 https://reactome.org/PathwayBrowser/#/R-DME-430347 MigFilin associates with Filamin and F-actin IEA Drosophila melanogaster 30616 R-DME-432148 https://reactome.org/PathwayBrowser/#/R-DME-432148 Fgr may phosphorylate p38 MAPK IEA Drosophila melanogaster 30616 R-DME-432232 https://reactome.org/PathwayBrowser/#/R-DME-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Drosophila melanogaster 30616 R-DME-432513 https://reactome.org/PathwayBrowser/#/R-DME-432513 CLK is phosphorylated by DCO TAS Drosophila melanogaster 30616 R-DME-432535 https://reactome.org/PathwayBrowser/#/R-DME-432535 TIM is phosphorylated by CK2 TAS Drosophila melanogaster 30616 R-DME-432559 https://reactome.org/PathwayBrowser/#/R-DME-432559 PER is phosphorylated by DCO TAS Drosophila melanogaster 30616 R-DME-432590 https://reactome.org/PathwayBrowser/#/R-DME-432590 Phosphorylated PER is phosphorylated by CK2 TAS Drosophila melanogaster 30616 R-DME-4332358 https://reactome.org/PathwayBrowser/#/R-DME-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Drosophila melanogaster 30616 R-DME-4332363 https://reactome.org/PathwayBrowser/#/R-DME-4332363 Autophosphorylation and activation of CAMK2 IEA Drosophila melanogaster 30616 R-DME-434382 https://reactome.org/PathwayBrowser/#/R-DME-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Drosophila melanogaster 30616 R-DME-437162 https://reactome.org/PathwayBrowser/#/R-DME-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-4411383 https://reactome.org/PathwayBrowser/#/R-DME-4411383 NLK phosphorylates TCF/LEF IEA Drosophila melanogaster 30616 R-DME-4411402 https://reactome.org/PathwayBrowser/#/R-DME-4411402 Activation of NLK IEA Drosophila melanogaster 30616 R-DME-442724 https://reactome.org/PathwayBrowser/#/R-DME-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Drosophila melanogaster 30616 R-DME-445072 https://reactome.org/PathwayBrowser/#/R-DME-445072 Interaction of PAK1 with Rac1-GTP IEA Drosophila melanogaster 30616 R-DME-445079 https://reactome.org/PathwayBrowser/#/R-DME-445079 Phosphorylation of L1 by ERK IEA Drosophila melanogaster 30616 R-DME-445699 https://reactome.org/PathwayBrowser/#/R-DME-445699 ATP Hydrolysis By Myosin IEA Drosophila melanogaster 30616 R-DME-445700 https://reactome.org/PathwayBrowser/#/R-DME-445700 Myosin Binds ATP IEA Drosophila melanogaster 30616 R-DME-447074 https://reactome.org/PathwayBrowser/#/R-DME-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Drosophila melanogaster 30616 R-DME-448955 https://reactome.org/PathwayBrowser/#/R-DME-448955 Phosphorylation of MEF2 proteins by p38 IEA Drosophila melanogaster 30616 R-DME-450088 https://reactome.org/PathwayBrowser/#/R-DME-450088 GLUT1 tetramer binds 4xATP IEA Drosophila melanogaster 30616 R-DME-450092 https://reactome.org/PathwayBrowser/#/R-DME-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Drosophila melanogaster 30616 R-DME-450222 https://reactome.org/PathwayBrowser/#/R-DME-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Drosophila melanogaster 30616 R-DME-450325 https://reactome.org/PathwayBrowser/#/R-DME-450325 c-FOS activation by phospho ERK1/2 IEA Drosophila melanogaster 30616 R-DME-450333 https://reactome.org/PathwayBrowser/#/R-DME-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Drosophila melanogaster 30616 R-DME-450337 https://reactome.org/PathwayBrowser/#/R-DME-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Drosophila melanogaster 30616 R-DME-450346 https://reactome.org/PathwayBrowser/#/R-DME-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Drosophila melanogaster 30616 R-DME-450463 https://reactome.org/PathwayBrowser/#/R-DME-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Drosophila melanogaster 30616 R-DME-450474 https://reactome.org/PathwayBrowser/#/R-DME-450474 MK2 phosphorylates BRF1 IEA Drosophila melanogaster 30616 R-DME-450490 https://reactome.org/PathwayBrowser/#/R-DME-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Drosophila melanogaster 30616 R-DME-450499 https://reactome.org/PathwayBrowser/#/R-DME-450499 Protein Kinase B (AKT) phosphorylates KSRP IEA Drosophila melanogaster 30616 R-DME-450533 https://reactome.org/PathwayBrowser/#/R-DME-450533 PKCdelta phosphorylates HuR IEA Drosophila melanogaster 30616 R-DME-450550 https://reactome.org/PathwayBrowser/#/R-DME-450550 PKCalpha phosphorylates HuR IEA Drosophila melanogaster 30616 R-DME-450723 https://reactome.org/PathwayBrowser/#/R-DME-450723 RAC1:GTP and MSN activate HEP TAS Drosophila melanogaster 30616 R-DME-450827 https://reactome.org/PathwayBrowser/#/R-DME-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Drosophila melanogaster 30616 R-DME-451856 https://reactome.org/PathwayBrowser/#/R-DME-451856 FT is phosphorylated by DCO TAS Drosophila melanogaster 30616 R-DME-453342 https://reactome.org/PathwayBrowser/#/R-DME-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Drosophila melanogaster 30616 R-DME-4793911 https://reactome.org/PathwayBrowser/#/R-DME-4793911 MAPKAPK2 phosphorylates HSF1 IEA Drosophila melanogaster 30616 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 30616 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 30616 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 30616 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 30616 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 30616 R-DME-504054 https://reactome.org/PathwayBrowser/#/R-DME-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Drosophila melanogaster 30616 R-DME-508040 https://reactome.org/PathwayBrowser/#/R-DME-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Drosophila melanogaster 30616 R-DME-5082387 https://reactome.org/PathwayBrowser/#/R-DME-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Drosophila melanogaster 30616 R-DME-5082405 https://reactome.org/PathwayBrowser/#/R-DME-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Drosophila melanogaster 30616 R-DME-508308 https://reactome.org/PathwayBrowser/#/R-DME-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Drosophila melanogaster 30616 R-DME-5195402 https://reactome.org/PathwayBrowser/#/R-DME-5195402 CDK1 phosphorylates LPIN IEA Drosophila melanogaster 30616 R-DME-5218804 https://reactome.org/PathwayBrowser/#/R-DME-5218804 p38 MAPK activation by VEGFR IEA Drosophila melanogaster 30616 R-DME-5218805 https://reactome.org/PathwayBrowser/#/R-DME-5218805 PKC autophosphorylates IEA Drosophila melanogaster 30616 R-DME-5218806 https://reactome.org/PathwayBrowser/#/R-DME-5218806 FYN autophosphorylates IEA Drosophila melanogaster 30616 R-DME-5218812 https://reactome.org/PathwayBrowser/#/R-DME-5218812 FYN phosphorylates PAK2 IEA Drosophila melanogaster 30616 R-DME-5218814 https://reactome.org/PathwayBrowser/#/R-DME-5218814 PAK2 autophorylates IEA Drosophila melanogaster 30616 R-DME-5218819 https://reactome.org/PathwayBrowser/#/R-DME-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-5218821 https://reactome.org/PathwayBrowser/#/R-DME-5218821 PDK1 phosphorylates PKC IEA Drosophila melanogaster 30616 R-DME-5218823 https://reactome.org/PathwayBrowser/#/R-DME-5218823 PKC phosphorylates sphingosine kinase 1 IEA Drosophila melanogaster 30616 R-DME-5218845 https://reactome.org/PathwayBrowser/#/R-DME-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Drosophila melanogaster 30616 R-DME-5218854 https://reactome.org/PathwayBrowser/#/R-DME-5218854 p-Y420-FYN is phosphorylated on S21 IEA Drosophila melanogaster 30616 R-DME-5218916 https://reactome.org/PathwayBrowser/#/R-DME-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Drosophila melanogaster 30616 R-DME-5229343 https://reactome.org/PathwayBrowser/#/R-DME-5229343 AXIN is phosphorylated in the destruction complex IEA Drosophila melanogaster 30616 R-DME-5244669 https://reactome.org/PathwayBrowser/#/R-DME-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Drosophila melanogaster 30616 R-DME-5251989 https://reactome.org/PathwayBrowser/#/R-DME-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Drosophila melanogaster 30616 R-DME-5339524 https://reactome.org/PathwayBrowser/#/R-DME-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Drosophila melanogaster 30616 R-DME-5357472 https://reactome.org/PathwayBrowser/#/R-DME-5357472 PAK1-3 autophosphorylates IEA Drosophila melanogaster 30616 R-DME-5357477 https://reactome.org/PathwayBrowser/#/R-DME-5357477 PAK1-3 phosphorylates VE-cadherin IEA Drosophila melanogaster 30616 R-DME-5357831 https://reactome.org/PathwayBrowser/#/R-DME-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Drosophila melanogaster 30616 R-DME-5358475 https://reactome.org/PathwayBrowser/#/R-DME-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Drosophila melanogaster 30616 R-DME-5358510 https://reactome.org/PathwayBrowser/#/R-DME-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Drosophila melanogaster 30616 R-DME-5358518 https://reactome.org/PathwayBrowser/#/R-DME-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Drosophila melanogaster 30616 R-DME-5358592 https://reactome.org/PathwayBrowser/#/R-DME-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Drosophila melanogaster 30616 R-DME-5358597 https://reactome.org/PathwayBrowser/#/R-DME-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Drosophila melanogaster 30616 R-DME-5358599 https://reactome.org/PathwayBrowser/#/R-DME-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Drosophila melanogaster 30616 R-DME-5358912 https://reactome.org/PathwayBrowser/#/R-DME-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Drosophila melanogaster 30616 R-DME-5362459 https://reactome.org/PathwayBrowser/#/R-DME-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Drosophila melanogaster 30616 R-DME-548843 https://reactome.org/PathwayBrowser/#/R-DME-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Drosophila melanogaster 30616 R-DME-5607726 https://reactome.org/PathwayBrowser/#/R-DME-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Drosophila melanogaster 30616 R-DME-5610720 https://reactome.org/PathwayBrowser/#/R-DME-5610720 PKA phosphorylates GLI3 IEA Drosophila melanogaster 30616 R-DME-5610722 https://reactome.org/PathwayBrowser/#/R-DME-5610722 CK1 phosphorylates p-GLI3 IEA Drosophila melanogaster 30616 R-DME-5610727 https://reactome.org/PathwayBrowser/#/R-DME-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Drosophila melanogaster 30616 R-DME-5610732 https://reactome.org/PathwayBrowser/#/R-DME-5610732 GSK3 phosphorylates p-GLI3 IEA Drosophila melanogaster 30616 R-DME-5617179 https://reactome.org/PathwayBrowser/#/R-DME-5617179 PRKACA phosphorylates TNNI3 IEA Drosophila melanogaster 30616 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 30616 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 30616 R-DME-5618085 https://reactome.org/PathwayBrowser/#/R-DME-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Drosophila melanogaster 30616 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 30616 R-DME-5618098 https://reactome.org/PathwayBrowser/#/R-DME-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Drosophila melanogaster 30616 R-DME-5618099 https://reactome.org/PathwayBrowser/#/R-DME-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 30616 R-DME-5618105 https://reactome.org/PathwayBrowser/#/R-DME-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Drosophila melanogaster 30616 R-DME-5618107 https://reactome.org/PathwayBrowser/#/R-DME-5618107 ATP binding to HSP90 triggers conformation change IEA Drosophila melanogaster 30616 R-DME-5618110 https://reactome.org/PathwayBrowser/#/R-DME-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Drosophila melanogaster 30616 R-DME-5621363 https://reactome.org/PathwayBrowser/#/R-DME-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Drosophila melanogaster 30616 R-DME-5623667 https://reactome.org/PathwayBrowser/#/R-DME-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Drosophila melanogaster 30616 R-DME-5624473 https://reactome.org/PathwayBrowser/#/R-DME-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Drosophila melanogaster 30616 R-DME-5624486 https://reactome.org/PathwayBrowser/#/R-DME-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Drosophila melanogaster 30616 R-DME-5624492 https://reactome.org/PathwayBrowser/#/R-DME-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Drosophila melanogaster 30616 R-DME-5625784 https://reactome.org/PathwayBrowser/#/R-DME-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Drosophila melanogaster 30616 R-DME-5627775 https://reactome.org/PathwayBrowser/#/R-DME-5627775 Autophosphorylation of PAK1,2,3 IEA Drosophila melanogaster 30616 R-DME-5635842 https://reactome.org/PathwayBrowser/#/R-DME-5635842 ULK3 phosphorylates GLI IEA Drosophila melanogaster 30616 R-DME-5654147 https://reactome.org/PathwayBrowser/#/R-DME-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Drosophila melanogaster 30616 R-DME-5654149 https://reactome.org/PathwayBrowser/#/R-DME-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Drosophila melanogaster 30616 R-DME-5654151 https://reactome.org/PathwayBrowser/#/R-DME-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Drosophila melanogaster 30616 R-DME-5654222 https://reactome.org/PathwayBrowser/#/R-DME-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Drosophila melanogaster 30616 R-DME-5654397 https://reactome.org/PathwayBrowser/#/R-DME-5654397 Activated FGFR2 phosphorylates FRS2 IEA Drosophila melanogaster 30616 R-DME-5654407 https://reactome.org/PathwayBrowser/#/R-DME-5654407 Activated FGFR2 phosphorylates SHC1 IEA Drosophila melanogaster 30616 R-DME-5654408 https://reactome.org/PathwayBrowser/#/R-DME-5654408 Activated FGFR3 phosphorylates FRS2 IEA Drosophila melanogaster 30616 R-DME-5654418 https://reactome.org/PathwayBrowser/#/R-DME-5654418 Activated FGFR4 phosphorylates FRS2 IEA Drosophila melanogaster 30616 R-DME-5654428 https://reactome.org/PathwayBrowser/#/R-DME-5654428 Activated FGFR4 phosphorylates SHC1 IEA Drosophila melanogaster 30616 R-DME-5654560 https://reactome.org/PathwayBrowser/#/R-DME-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Drosophila melanogaster 30616 R-DME-5654562 https://reactome.org/PathwayBrowser/#/R-DME-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Drosophila melanogaster 30616 R-DME-5654565 https://reactome.org/PathwayBrowser/#/R-DME-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Drosophila melanogaster 30616 R-DME-5654566 https://reactome.org/PathwayBrowser/#/R-DME-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Drosophila melanogaster 30616 R-DME-5654575 https://reactome.org/PathwayBrowser/#/R-DME-5654575 Activated FGFR1 phosphorylates FRS2 IEA Drosophila melanogaster 30616 R-DME-5654578 https://reactome.org/PathwayBrowser/#/R-DME-5654578 Activated FGFR1 phosphorylates FRS3 IEA Drosophila melanogaster 30616 R-DME-5654582 https://reactome.org/PathwayBrowser/#/R-DME-5654582 Activated FGFR1 phosphorylates SHC1 IEA Drosophila melanogaster 30616 R-DME-5654587 https://reactome.org/PathwayBrowser/#/R-DME-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Drosophila melanogaster 30616 R-DME-5654605 https://reactome.org/PathwayBrowser/#/R-DME-5654605 Activated FGFR2 phosphorylates FRS3 IEA Drosophila melanogaster 30616 R-DME-5654607 https://reactome.org/PathwayBrowser/#/R-DME-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Drosophila melanogaster 30616 R-DME-5654628 https://reactome.org/PathwayBrowser/#/R-DME-5654628 Activated FGFR3 phosphorylates FRS3 IEA Drosophila melanogaster 30616 R-DME-5654631 https://reactome.org/PathwayBrowser/#/R-DME-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Drosophila melanogaster 30616 R-DME-5654634 https://reactome.org/PathwayBrowser/#/R-DME-5654634 Activated FGFR3 phosphorylates SHC1 IEA Drosophila melanogaster 30616 R-DME-5654653 https://reactome.org/PathwayBrowser/#/R-DME-5654653 Activated FGFR4 phosphorylates FRS3 IEA Drosophila melanogaster 30616 R-DME-5654655 https://reactome.org/PathwayBrowser/#/R-DME-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Drosophila melanogaster 30616 R-DME-5654690 https://reactome.org/PathwayBrowser/#/R-DME-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-5654692 https://reactome.org/PathwayBrowser/#/R-DME-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-5654697 https://reactome.org/PathwayBrowser/#/R-DME-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-5654701 https://reactome.org/PathwayBrowser/#/R-DME-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-5654705 https://reactome.org/PathwayBrowser/#/R-DME-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-5654709 https://reactome.org/PathwayBrowser/#/R-DME-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-5654714 https://reactome.org/PathwayBrowser/#/R-DME-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-5654717 https://reactome.org/PathwayBrowser/#/R-DME-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-5654989 https://reactome.org/PathwayBrowser/#/R-DME-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Drosophila melanogaster 30616 R-DME-5662466 https://reactome.org/PathwayBrowser/#/R-DME-5662466 XYLB phosphorylates D-xylulose IEA Drosophila melanogaster 30616 R-DME-5665868 https://reactome.org/PathwayBrowser/#/R-DME-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Drosophila melanogaster 30616 R-DME-5668932 https://reactome.org/PathwayBrowser/#/R-DME-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Drosophila melanogaster 30616 R-DME-5668947 https://reactome.org/PathwayBrowser/#/R-DME-5668947 PAK1 phosphorylates myosin phosphatase IEA Drosophila melanogaster 30616 R-DME-5669250 https://reactome.org/PathwayBrowser/#/R-DME-5669250 PAK1 phosphorylates FLNA IEA Drosophila melanogaster 30616 R-DME-5671749 https://reactome.org/PathwayBrowser/#/R-DME-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Drosophila melanogaster 30616 R-DME-5671763 https://reactome.org/PathwayBrowser/#/R-DME-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Drosophila melanogaster 30616 R-DME-5672008 https://reactome.org/PathwayBrowser/#/R-DME-5672008 Thr-180 of ULK1 is phosphorylated IEA Drosophila melanogaster 30616 R-DME-5672010 https://reactome.org/PathwayBrowser/#/R-DME-5672010 Active MTORC1 phosphorylates ULK1 IEA Drosophila melanogaster 30616 R-DME-5672012 https://reactome.org/PathwayBrowser/#/R-DME-5672012 Beclin-1 complex phosphorylates PtdIns IEA Drosophila melanogaster 30616 R-DME-5672828 https://reactome.org/PathwayBrowser/#/R-DME-5672828 mTORC1 phosphorylates AKT1S1 IEA Drosophila melanogaster 30616 R-DME-5672948 https://reactome.org/PathwayBrowser/#/R-DME-5672948 MARK3 phosphorylates KSR1 IEA Drosophila melanogaster 30616 R-DME-5672969 https://reactome.org/PathwayBrowser/#/R-DME-5672969 Phosphorylation of RAF IEA Drosophila melanogaster 30616 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 30616 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 30616 R-DME-5673768 https://reactome.org/PathwayBrowser/#/R-DME-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Drosophila melanogaster 30616 R-DME-5674130 https://reactome.org/PathwayBrowser/#/R-DME-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Drosophila melanogaster 30616 R-DME-5674373 https://reactome.org/PathwayBrowser/#/R-DME-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Drosophila melanogaster 30616 R-DME-5674496 https://reactome.org/PathwayBrowser/#/R-DME-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Drosophila melanogaster 30616 R-DME-5675194 https://reactome.org/PathwayBrowser/#/R-DME-5675194 Activated MAPK phosphorylates RAF1 IEA Drosophila melanogaster 30616 R-DME-5675198 https://reactome.org/PathwayBrowser/#/R-DME-5675198 Activated MAPKs phosphorylate BRAF IEA Drosophila melanogaster 30616 R-DME-5675868 https://reactome.org/PathwayBrowser/#/R-DME-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Drosophila melanogaster 30616 R-DME-5678863 https://reactome.org/PathwayBrowser/#/R-DME-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Drosophila melanogaster 30616 R-DME-5679041 https://reactome.org/PathwayBrowser/#/R-DME-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 30616 R-DME-5679205 https://reactome.org/PathwayBrowser/#/R-DME-5679205 ULK1 phosphorylates Beclin-1 IEA Drosophila melanogaster 30616 R-DME-5682026 https://reactome.org/PathwayBrowser/#/R-DME-5682026 MRN bound to shortened telomeres activates ATM IEA Drosophila melanogaster 30616 R-DME-5682101 https://reactome.org/PathwayBrowser/#/R-DME-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Drosophila melanogaster 30616 R-DME-5682285 https://reactome.org/PathwayBrowser/#/R-DME-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Drosophila melanogaster 30616 R-DME-5682598 https://reactome.org/PathwayBrowser/#/R-DME-5682598 ATM phosphorylates HERC2 IEA Drosophila melanogaster 30616 R-DME-5682983 https://reactome.org/PathwayBrowser/#/R-DME-5682983 ATM phosphorylates WHSC1 IEA Drosophila melanogaster 30616 R-DME-5683714 https://reactome.org/PathwayBrowser/#/R-DME-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Drosophila melanogaster 30616 R-DME-5683792 https://reactome.org/PathwayBrowser/#/R-DME-5683792 p-T68-CHEK2 autophosphorylates IEA Drosophila melanogaster 30616 R-DME-5683964 https://reactome.org/PathwayBrowser/#/R-DME-5683964 ATM phosphorylates EYA1-4 IEA Drosophila melanogaster 30616 R-DME-5684096 https://reactome.org/PathwayBrowser/#/R-DME-5684096 CDK2 phosphorylates RBBP8 IEA Drosophila melanogaster 30616 R-DME-5684140 https://reactome.org/PathwayBrowser/#/R-DME-5684140 ATM phosphorylates RBBP8 IEA Drosophila melanogaster 30616 R-DME-5684887 https://reactome.org/PathwayBrowser/#/R-DME-5684887 Activation of CHEK1 at resected DNA DSBs IEA Drosophila melanogaster 30616 R-DME-5685156 https://reactome.org/PathwayBrowser/#/R-DME-5685156 ATR phosphorylates RPA2 IEA Drosophila melanogaster 30616 R-DME-5685230 https://reactome.org/PathwayBrowser/#/R-DME-5685230 CHEK1 phosphorylates RAD51 IEA Drosophila melanogaster 30616 R-DME-5686578 https://reactome.org/PathwayBrowser/#/R-DME-5686578 Activated ATM phosphorylates ABL1 IEA Drosophila melanogaster 30616 R-DME-5690996 https://reactome.org/PathwayBrowser/#/R-DME-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Drosophila melanogaster 30616 R-DME-5692462 https://reactome.org/PathwayBrowser/#/R-DME-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Drosophila melanogaster 30616 R-DME-5693536 https://reactome.org/PathwayBrowser/#/R-DME-5693536 ATM phosphorylates MDC1 IEA Drosophila melanogaster 30616 R-DME-5693540 https://reactome.org/PathwayBrowser/#/R-DME-5693540 MRN activates ATM IEA Drosophila melanogaster 30616 R-DME-5693549 https://reactome.org/PathwayBrowser/#/R-DME-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Drosophila melanogaster 30616 R-DME-5693598 https://reactome.org/PathwayBrowser/#/R-DME-5693598 ATM phosphorylates NBN IEA Drosophila melanogaster 30616 R-DME-5693609 https://reactome.org/PathwayBrowser/#/R-DME-5693609 ATM phosphorylates TP53 at S15 IEA Drosophila melanogaster 30616 R-DME-5694425 https://reactome.org/PathwayBrowser/#/R-DME-5694425 NSF ATPase activity dissociates cis-SNARE IEA Drosophila melanogaster 30616 R-DME-5695957 https://reactome.org/PathwayBrowser/#/R-DME-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Drosophila melanogaster 30616 R-DME-5696004 https://reactome.org/PathwayBrowser/#/R-DME-5696004 ACSF2 ligates CoA-SH to MCFA IEA Drosophila melanogaster 30616 R-DME-5696007 https://reactome.org/PathwayBrowser/#/R-DME-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Drosophila melanogaster 30616 R-DME-5696074 https://reactome.org/PathwayBrowser/#/R-DME-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Drosophila melanogaster 30616 R-DME-5696839 https://reactome.org/PathwayBrowser/#/R-DME-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Drosophila melanogaster 30616 R-DME-6782131 https://reactome.org/PathwayBrowser/#/R-DME-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Drosophila melanogaster 30616 R-DME-6788798 https://reactome.org/PathwayBrowser/#/R-DME-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 30616 R-DME-6788810 https://reactome.org/PathwayBrowser/#/R-DME-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 30616 R-DME-6797606 https://reactome.org/PathwayBrowser/#/R-DME-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Drosophila melanogaster 30616 R-DME-6798174 https://reactome.org/PathwayBrowser/#/R-DME-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Drosophila melanogaster 30616 R-DME-6798372 https://reactome.org/PathwayBrowser/#/R-DME-6798372 ATM phosphorylates DYRK2 IEA Drosophila melanogaster 30616 R-DME-6798374 https://reactome.org/PathwayBrowser/#/R-DME-6798374 DYRK2 phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-6799097 https://reactome.org/PathwayBrowser/#/R-DME-6799097 ATM phosphorylates ZNF420 IEA Drosophila melanogaster 30616 R-DME-6799246 https://reactome.org/PathwayBrowser/#/R-DME-6799246 CHEK1 phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-6799332 https://reactome.org/PathwayBrowser/#/R-DME-6799332 ATR phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-6799409 https://reactome.org/PathwayBrowser/#/R-DME-6799409 HIPK2 phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-6799495 https://reactome.org/PathwayBrowser/#/R-DME-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Drosophila melanogaster 30616 R-DME-6800490 https://reactome.org/PathwayBrowser/#/R-DME-6800490 ATM phosphorylates PIDD1 IEA Drosophila melanogaster 30616 R-DME-6801342 https://reactome.org/PathwayBrowser/#/R-DME-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Drosophila melanogaster 30616 R-DME-6801456 https://reactome.org/PathwayBrowser/#/R-DME-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Drosophila melanogaster 30616 R-DME-6803771 https://reactome.org/PathwayBrowser/#/R-DME-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Drosophila melanogaster 30616 R-DME-6804596 https://reactome.org/PathwayBrowser/#/R-DME-6804596 APAF1:CYCS binds APIP IEA Drosophila melanogaster 30616 R-DME-6805059 https://reactome.org/PathwayBrowser/#/R-DME-6805059 CK2:FACT phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-6805109 https://reactome.org/PathwayBrowser/#/R-DME-6805109 CDK2 phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-6805126 https://reactome.org/PathwayBrowser/#/R-DME-6805126 AURKB phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-6805276 https://reactome.org/PathwayBrowser/#/R-DME-6805276 CDK5 phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-6805399 https://reactome.org/PathwayBrowser/#/R-DME-6805399 TAF1 phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-6805470 https://reactome.org/PathwayBrowser/#/R-DME-6805470 AMPK phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-6805479 https://reactome.org/PathwayBrowser/#/R-DME-6805479 TP53RK phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-6805640 https://reactome.org/PathwayBrowser/#/R-DME-6805640 AKT phosphorylates KAT6A IEA Drosophila melanogaster 30616 R-DME-6805785 https://reactome.org/PathwayBrowser/#/R-DME-6805785 AKT phosphorylates PHF20 IEA Drosophila melanogaster 30616 R-DME-6806877 https://reactome.org/PathwayBrowser/#/R-DME-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Drosophila melanogaster 30616 R-DME-6806967 https://reactome.org/PathwayBrowser/#/R-DME-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Drosophila melanogaster 30616 R-DME-6807868 https://reactome.org/PathwayBrowser/#/R-DME-6807868 GBF1 stimulates ARF nucleotide exchange IEA Drosophila melanogaster 30616 R-DME-6810233 https://reactome.org/PathwayBrowser/#/R-DME-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Drosophila melanogaster 30616 R-DME-6811422 https://reactome.org/PathwayBrowser/#/R-DME-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Drosophila melanogaster 30616 R-DME-6811522 https://reactome.org/PathwayBrowser/#/R-DME-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Drosophila melanogaster 30616 R-DME-6814120 https://reactome.org/PathwayBrowser/#/R-DME-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Drosophila melanogaster 30616 R-DME-6814124 https://reactome.org/PathwayBrowser/#/R-DME-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Drosophila melanogaster 30616 R-DME-6814409 https://reactome.org/PathwayBrowser/#/R-DME-6814409 CK2 phosphorylates PDCL IEA Drosophila melanogaster 30616 R-DME-6814549 https://reactome.org/PathwayBrowser/#/R-DME-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Drosophila melanogaster 30616 R-DME-6814559 https://reactome.org/PathwayBrowser/#/R-DME-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Drosophila melanogaster 30616 R-DME-6814670 https://reactome.org/PathwayBrowser/#/R-DME-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Drosophila melanogaster 30616 R-DME-6814675 https://reactome.org/PathwayBrowser/#/R-DME-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Drosophila melanogaster 30616 R-DME-6814678 https://reactome.org/PathwayBrowser/#/R-DME-6814678 ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN IEA Drosophila melanogaster 30616 R-DME-68610 https://reactome.org/PathwayBrowser/#/R-DME-68610 Formation of ORC(2-5) complex IEA Drosophila melanogaster 30616 R-DME-68944 https://reactome.org/PathwayBrowser/#/R-DME-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Drosophila melanogaster 30616 R-DME-69005 https://reactome.org/PathwayBrowser/#/R-DME-69005 Cdc6 protein is phosphorylated by CDK IEA Drosophila melanogaster 30616 R-DME-69015 https://reactome.org/PathwayBrowser/#/R-DME-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Drosophila melanogaster 30616 R-DME-69063 https://reactome.org/PathwayBrowser/#/R-DME-69063 Loading of PCNA - Sliding Clamp Formation IEA Drosophila melanogaster 30616 R-DME-69195 https://reactome.org/PathwayBrowser/#/R-DME-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Drosophila melanogaster 30616 R-DME-69604 https://reactome.org/PathwayBrowser/#/R-DME-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Drosophila melanogaster 30616 R-DME-69608 https://reactome.org/PathwayBrowser/#/R-DME-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Drosophila melanogaster 30616 R-DME-69685 https://reactome.org/PathwayBrowser/#/R-DME-69685 CHEK2 phosphorylates TP53 IEA Drosophila melanogaster 30616 R-DME-70333 https://reactome.org/PathwayBrowser/#/R-DME-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Drosophila melanogaster 30616 R-DME-70420 https://reactome.org/PathwayBrowser/#/R-DME-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Drosophila melanogaster 30616 R-DME-70467 https://reactome.org/PathwayBrowser/#/R-DME-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Drosophila melanogaster 30616 R-DME-70486 https://reactome.org/PathwayBrowser/#/R-DME-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Drosophila melanogaster 30616 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 30616 R-DME-70606 https://reactome.org/PathwayBrowser/#/R-DME-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Drosophila melanogaster 30616 R-DME-70773 https://reactome.org/PathwayBrowser/#/R-DME-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Drosophila melanogaster 30616 R-DME-70967 https://reactome.org/PathwayBrowser/#/R-DME-70967 IDH3 complex decarboxylates isocitrate IEA Drosophila melanogaster 30616 R-DME-70997 https://reactome.org/PathwayBrowser/#/R-DME-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Drosophila melanogaster 30616 R-DME-71401 https://reactome.org/PathwayBrowser/#/R-DME-71401 OGDH dimer decarboxylates 2-OG IEA Drosophila melanogaster 30616 R-DME-71541 https://reactome.org/PathwayBrowser/#/R-DME-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Drosophila melanogaster 30616 R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 30616 R-DME-71735 https://reactome.org/PathwayBrowser/#/R-DME-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Drosophila melanogaster 30616 R-DME-71802 https://reactome.org/PathwayBrowser/#/R-DME-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Drosophila melanogaster 30616 R-DME-71850 https://reactome.org/PathwayBrowser/#/R-DME-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Drosophila melanogaster 30616 R-DME-72180 https://reactome.org/PathwayBrowser/#/R-DME-72180 Cleavage of mRNA at the 3'-end IEA Drosophila melanogaster 30616 R-DME-72185 https://reactome.org/PathwayBrowser/#/R-DME-72185 mRNA polyadenylation IEA Drosophila melanogaster 30616 R-DME-72621 https://reactome.org/PathwayBrowser/#/R-DME-72621 Ribosomal scanning IEA Drosophila melanogaster 30616 R-DME-73548 https://reactome.org/PathwayBrowser/#/R-DME-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Drosophila melanogaster 30616 R-DME-73577 https://reactome.org/PathwayBrowser/#/R-DME-73577 CAD hexamer transforms L-Gln to CAP IEA Drosophila melanogaster 30616 R-DME-73599 https://reactome.org/PathwayBrowser/#/R-DME-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Drosophila melanogaster 30616 R-DME-73635 https://reactome.org/PathwayBrowser/#/R-DME-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Drosophila melanogaster 30616 R-DME-73647 https://reactome.org/PathwayBrowser/#/R-DME-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Drosophila melanogaster 30616 R-DME-73788 https://reactome.org/PathwayBrowser/#/R-DME-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Drosophila melanogaster 30616 R-DME-73792 https://reactome.org/PathwayBrowser/#/R-DME-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Drosophila melanogaster 30616 R-DME-73805 https://reactome.org/PathwayBrowser/#/R-DME-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Drosophila melanogaster 30616 R-DME-73810 https://reactome.org/PathwayBrowser/#/R-DME-73810 FGAM + ATP => AIR + ADP + Pi IEA Drosophila melanogaster 30616 R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 30616 R-DME-73814 https://reactome.org/PathwayBrowser/#/R-DME-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Drosophila melanogaster 30616 R-DME-74220 https://reactome.org/PathwayBrowser/#/R-DME-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Drosophila melanogaster 30616 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 30616 R-DME-75010 https://reactome.org/PathwayBrowser/#/R-DME-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Drosophila melanogaster 30616 R-DME-75125 https://reactome.org/PathwayBrowser/#/R-DME-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Drosophila melanogaster 30616 R-DME-75126 https://reactome.org/PathwayBrowser/#/R-DME-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Drosophila melanogaster 30616 R-DME-75809 https://reactome.org/PathwayBrowser/#/R-DME-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Drosophila melanogaster 30616 R-DME-75848 https://reactome.org/PathwayBrowser/#/R-DME-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Drosophila melanogaster 30616 R-DME-75851 https://reactome.org/PathwayBrowser/#/R-DME-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 30616 R-DME-75887 https://reactome.org/PathwayBrowser/#/R-DME-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Drosophila melanogaster 30616 R-DME-75949 https://reactome.org/PathwayBrowser/#/R-DME-75949 RNA Polymerase II Promoter Opening: First Transition IEA Drosophila melanogaster 30616 R-DME-77071 https://reactome.org/PathwayBrowser/#/R-DME-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Drosophila melanogaster 30616 R-DME-881988 https://reactome.org/PathwayBrowser/#/R-DME-881988 CRY is phosphorylated by SGG TAS Drosophila melanogaster 30616 R-DME-8847977 https://reactome.org/PathwayBrowser/#/R-DME-8847977 FRK phosphorylates PTEN IEA Drosophila melanogaster 30616 R-DME-8849353 https://reactome.org/PathwayBrowser/#/R-DME-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Drosophila melanogaster 30616 R-DME-8850945 https://reactome.org/PathwayBrowser/#/R-DME-8850945 Casein kinase II phosphorylates PTEN IEA Drosophila melanogaster 30616 R-DME-8851797 https://reactome.org/PathwayBrowser/#/R-DME-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Drosophila melanogaster 30616 R-DME-8852128 https://reactome.org/PathwayBrowser/#/R-DME-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Drosophila melanogaster 30616 R-DME-8852131 https://reactome.org/PathwayBrowser/#/R-DME-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Drosophila melanogaster 30616 R-DME-8852132 https://reactome.org/PathwayBrowser/#/R-DME-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Drosophila melanogaster 30616 R-DME-8852134 https://reactome.org/PathwayBrowser/#/R-DME-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Drosophila melanogaster 30616 R-DME-8853774 https://reactome.org/PathwayBrowser/#/R-DME-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Drosophila melanogaster 30616 R-DME-8856813 https://reactome.org/PathwayBrowser/#/R-DME-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Drosophila melanogaster 30616 R-DME-8857925 https://reactome.org/PathwayBrowser/#/R-DME-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Drosophila melanogaster 30616 R-DME-8867041 https://reactome.org/PathwayBrowser/#/R-DME-8867041 EGFR phosphorylates EPS15 IEA Drosophila melanogaster 30616 R-DME-8868066 https://reactome.org/PathwayBrowser/#/R-DME-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Drosophila melanogaster 30616 R-DME-8868072 https://reactome.org/PathwayBrowser/#/R-DME-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Drosophila melanogaster 30616 R-DME-8868118 https://reactome.org/PathwayBrowser/#/R-DME-8868118 MAPK12 phosphorylates PTPN3 IEA Drosophila melanogaster 30616 R-DME-8868236 https://reactome.org/PathwayBrowser/#/R-DME-8868236 BAR domain proteins recruit dynamin IEA Drosophila melanogaster 30616 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster 30616 R-DME-8868651 https://reactome.org/PathwayBrowser/#/R-DME-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Drosophila melanogaster 30616 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster 30616 R-DME-8868660 https://reactome.org/PathwayBrowser/#/R-DME-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Drosophila melanogaster 30616 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster 30616 R-DME-8869606 https://reactome.org/PathwayBrowser/#/R-DME-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 30616 R-DME-8869607 https://reactome.org/PathwayBrowser/#/R-DME-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 30616 R-DME-8869627 https://reactome.org/PathwayBrowser/#/R-DME-8869627 NMRK2 phosphorylates NR to yield NMN IEA Drosophila melanogaster 30616 R-DME-8869633 https://reactome.org/PathwayBrowser/#/R-DME-8869633 NMRK1 phosphorylates NR to yield NMN IEA Drosophila melanogaster 30616 R-DME-8871194 https://reactome.org/PathwayBrowser/#/R-DME-8871194 RAB5 and GAPVD1 bind AP-2 IEA Drosophila melanogaster 30616 R-DME-8871373 https://reactome.org/PathwayBrowser/#/R-DME-8871373 BMX phosphorylates RUFY1 IEA Drosophila melanogaster 30616 R-DME-8875071 https://reactome.org/PathwayBrowser/#/R-DME-8875071 ACSS3 ligates CoA to CH3COO- IEA Drosophila melanogaster 30616 R-DME-8876889 https://reactome.org/PathwayBrowser/#/R-DME-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 30616 R-DME-8877691 https://reactome.org/PathwayBrowser/#/R-DME-8877691 MAP2K6 phosphorylates PIP4K2B IEA Drosophila melanogaster 30616 R-DME-8878050 https://reactome.org/PathwayBrowser/#/R-DME-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Drosophila melanogaster 30616 R-DME-8878054 https://reactome.org/PathwayBrowser/#/R-DME-8878054 HIPK2 phosphorylates RUNX1 IEA Drosophila melanogaster 30616 R-DME-8933446 https://reactome.org/PathwayBrowser/#/R-DME-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Drosophila melanogaster 30616 R-DME-8934446 https://reactome.org/PathwayBrowser/#/R-DME-8934446 Activated PKC phosphorylates SHC1 IEA Drosophila melanogaster 30616 R-DME-8937807 https://reactome.org/PathwayBrowser/#/R-DME-8937807 SRC phosphorylates RUNX3 IEA Drosophila melanogaster 30616 R-DME-8939204 https://reactome.org/PathwayBrowser/#/R-DME-8939204 ESTG binds ESR1:chaperone complex IEA Drosophila melanogaster 30616 R-DME-8939959 https://reactome.org/PathwayBrowser/#/R-DME-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Drosophila melanogaster 30616 R-DME-8942607 https://reactome.org/PathwayBrowser/#/R-DME-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Drosophila melanogaster 30616 R-DME-8942836 https://reactome.org/PathwayBrowser/#/R-DME-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Drosophila melanogaster 30616 R-DME-8944454 https://reactome.org/PathwayBrowser/#/R-DME-8944454 mTORC1 phosphorylates MAF1 IEA Drosophila melanogaster 30616 R-DME-8948039 https://reactome.org/PathwayBrowser/#/R-DME-8948039 FUNDC1 is phosphorylated by CK2 IEA Drosophila melanogaster 30616 R-DME-8948143 https://reactome.org/PathwayBrowser/#/R-DME-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Drosophila melanogaster 30616 R-DME-8948146 https://reactome.org/PathwayBrowser/#/R-DME-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Drosophila melanogaster 30616 R-DME-8948757 https://reactome.org/PathwayBrowser/#/R-DME-8948757 AKT phosphorylates MKRN1 IEA Drosophila melanogaster 30616 R-DME-8951648 https://reactome.org/PathwayBrowser/#/R-DME-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Drosophila melanogaster 30616 R-DME-8951656 https://reactome.org/PathwayBrowser/#/R-DME-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Drosophila melanogaster 30616 R-DME-8952289 https://reactome.org/PathwayBrowser/#/R-DME-8952289 FAM20C phosphorylates FAM20C substrates IEA Drosophila melanogaster 30616 R-DME-8954327 https://reactome.org/PathwayBrowser/#/R-DME-8954327 UCKL1 phosphorylates urindine, cytidine IEA Drosophila melanogaster 30616 R-DME-8955030 https://reactome.org/PathwayBrowser/#/R-DME-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 30616 R-DME-8955844 https://reactome.org/PathwayBrowser/#/R-DME-8955844 RBKS phosphorylates ribose to R5P IEA Drosophila melanogaster 30616 R-DME-8959510 https://reactome.org/PathwayBrowser/#/R-DME-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Drosophila melanogaster 30616 R-DME-8964242 https://reactome.org/PathwayBrowser/#/R-DME-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Drosophila melanogaster 30616 R-DME-9007539 https://reactome.org/PathwayBrowser/#/R-DME-9007539 CHEK1 phosphorylates E2F6 IEA Drosophila melanogaster 30616 R-DME-9008043 https://reactome.org/PathwayBrowser/#/R-DME-9008043 MAPK8 phosphorylation IEA Drosophila melanogaster 30616 R-DME-9008412 https://reactome.org/PathwayBrowser/#/R-DME-9008412 CDK4 phosphorylates RUNX2 IEA Drosophila melanogaster 30616 R-DME-9008684 https://reactome.org/PathwayBrowser/#/R-DME-9008684 TBK1 phosphorylation IEA Drosophila melanogaster 30616 R-DME-9009072 https://reactome.org/PathwayBrowser/#/R-DME-9009072 STAT3 phosphorylation IEA Drosophila melanogaster 30616 R-DME-9009282 https://reactome.org/PathwayBrowser/#/R-DME-9009282 CDK1 phosphorylates RUNX2 IEA Drosophila melanogaster 30616 R-DME-9009950 https://reactome.org/PathwayBrowser/#/R-DME-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Drosophila melanogaster 30616 R-DME-9012268 https://reactome.org/PathwayBrowser/#/R-DME-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 30616 R-DME-9012319 https://reactome.org/PathwayBrowser/#/R-DME-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Drosophila melanogaster 30616 R-DME-9021609 https://reactome.org/PathwayBrowser/#/R-DME-9021609 ESR-associated SRC autophosphorylates IEA Drosophila melanogaster 30616 R-DME-9021627 https://reactome.org/PathwayBrowser/#/R-DME-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 30616 R-DME-9038161 https://reactome.org/PathwayBrowser/#/R-DME-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Drosophila melanogaster 30616 R-DME-913996 https://reactome.org/PathwayBrowser/#/R-DME-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Drosophila melanogaster 30616 R-DME-917693 https://reactome.org/PathwayBrowser/#/R-DME-917693 ESCRT Disassembly IEA Drosophila melanogaster 30616 R-DME-917841 https://reactome.org/PathwayBrowser/#/R-DME-917841 Acidification of Tf:TfR1 containing endosome IEA Drosophila melanogaster 30616 R-DME-917979 https://reactome.org/PathwayBrowser/#/R-DME-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Drosophila melanogaster 30616 R-DME-927889 https://reactome.org/PathwayBrowser/#/R-DME-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Drosophila melanogaster 30616 R-DME-934559 https://reactome.org/PathwayBrowser/#/R-DME-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Drosophila melanogaster 30616 R-DME-936883 https://reactome.org/PathwayBrowser/#/R-DME-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Drosophila melanogaster 30616 R-DME-936895 https://reactome.org/PathwayBrowser/#/R-DME-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Drosophila melanogaster 30616 R-DME-937034 https://reactome.org/PathwayBrowser/#/R-DME-937034 IRAK1 phosphorylates Pellino IEA Drosophila melanogaster 30616 R-DME-939763 https://reactome.org/PathwayBrowser/#/R-DME-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Drosophila melanogaster 30616 R-DME-947531 https://reactome.org/PathwayBrowser/#/R-DME-947531 Molybdenum ion transfer onto molybdopterin IEA Drosophila melanogaster 30616 R-DME-947591 https://reactome.org/PathwayBrowser/#/R-DME-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Drosophila melanogaster 30616 R-DME-9604328 https://reactome.org/PathwayBrowser/#/R-DME-9604328 AKT1 phosphorylates NOTCH4 IEA Drosophila melanogaster 30616 R-DME-9610153 https://reactome.org/PathwayBrowser/#/R-DME-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Drosophila melanogaster 30616 R-DME-9610156 https://reactome.org/PathwayBrowser/#/R-DME-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Drosophila melanogaster 30616 R-DME-9610163 https://reactome.org/PathwayBrowser/#/R-DME-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Drosophila melanogaster 30616 R-DME-9613494 https://reactome.org/PathwayBrowser/#/R-DME-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Drosophila melanogaster 30616 R-DME-9624526 https://reactome.org/PathwayBrowser/#/R-DME-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Drosophila melanogaster 30616 R-DME-9627056 https://reactome.org/PathwayBrowser/#/R-DME-9627056 Procaspase 9 forms dimer IEA Drosophila melanogaster 30616 R-DME-9627089 https://reactome.org/PathwayBrowser/#/R-DME-9627089 CASP9 is phosphorylated at T412 IEA Drosophila melanogaster 30616 R-DME-9632858 https://reactome.org/PathwayBrowser/#/R-DME-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Drosophila melanogaster 30616 R-DME-964958 https://reactome.org/PathwayBrowser/#/R-DME-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Drosophila melanogaster 30616 R-DME-964962 https://reactome.org/PathwayBrowser/#/R-DME-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Drosophila melanogaster 30616 R-DME-964970 https://reactome.org/PathwayBrowser/#/R-DME-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Drosophila melanogaster 30616 R-DME-9653503 https://reactome.org/PathwayBrowser/#/R-DME-9653503 KRAS4B is phosphorylated on serine 181 IEA Drosophila melanogaster 30616 R-DME-9661417 https://reactome.org/PathwayBrowser/#/R-DME-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 30616 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 30616 R-DME-9684118 https://reactome.org/PathwayBrowser/#/R-DME-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Drosophila melanogaster 30616 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 30616 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 30616 R-DME-9699579 https://reactome.org/PathwayBrowser/#/R-DME-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Drosophila melanogaster 30616 R-DME-9705925 https://reactome.org/PathwayBrowser/#/R-DME-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Drosophila melanogaster 30616 R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 30616 R-DME-9706390 https://reactome.org/PathwayBrowser/#/R-DME-9706390 RHOBTB3 binds interacting proteins at trans-Golgi network IEA Drosophila melanogaster 30616 R-DME-9706393 https://reactome.org/PathwayBrowser/#/R-DME-9706393 RHOBTB3 binds ATP IEA Drosophila melanogaster 30616 R-DME-9706399 https://reactome.org/PathwayBrowser/#/R-DME-9706399 RHOBTB3 hydrolyzes ATP IEA Drosophila melanogaster 30616 R-DME-9706837 https://reactome.org/PathwayBrowser/#/R-DME-9706837 AR binds AR antagonists IEA Drosophila melanogaster 30616 R-DME-9709547 https://reactome.org/PathwayBrowser/#/R-DME-9709547 ESTG binds ESR2:chaperone complex IEA Drosophila melanogaster 30616 R-DME-9716913 https://reactome.org/PathwayBrowser/#/R-DME-9716913 ESR1 binds ESR1 antagonists IEA Drosophila melanogaster 30616 R-DME-9716947 https://reactome.org/PathwayBrowser/#/R-DME-9716947 ESR1 binds ESR1 agonists IEA Drosophila melanogaster 30616 R-DME-9725855 https://reactome.org/PathwayBrowser/#/R-DME-9725855 NR3C2 binds NR3C2 antagonists IEA Drosophila melanogaster 30616 R-DME-9725885 https://reactome.org/PathwayBrowser/#/R-DME-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Drosophila melanogaster 30616 R-DME-9726509 https://reactome.org/PathwayBrowser/#/R-DME-9726509 NR3C2 binds fludrocortisone IEA Drosophila melanogaster 30616 R-DME-9726580 https://reactome.org/PathwayBrowser/#/R-DME-9726580 PGR binds PGR agonists IEA Drosophila melanogaster 30616 R-DME-9726621 https://reactome.org/PathwayBrowser/#/R-DME-9726621 PGR binds PGR antagonists IEA Drosophila melanogaster 30616 R-DME-9731111 https://reactome.org/PathwayBrowser/#/R-DME-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Drosophila melanogaster 30616 R-DME-9734535 https://reactome.org/PathwayBrowser/#/R-DME-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Drosophila melanogaster 30616 R-DME-9734547 https://reactome.org/PathwayBrowser/#/R-DME-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Drosophila melanogaster 30616 R-DME-9734687 https://reactome.org/PathwayBrowser/#/R-DME-9734687 ORC6 is phosphorylated on T195 IEA Drosophila melanogaster 30616 R-DME-9748949 https://reactome.org/PathwayBrowser/#/R-DME-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Drosophila melanogaster 30616 R-DME-9748957 https://reactome.org/PathwayBrowser/#/R-DME-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Drosophila melanogaster 30616 R-DME-9748963 https://reactome.org/PathwayBrowser/#/R-DME-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Drosophila melanogaster 30616 R-DME-9748969 https://reactome.org/PathwayBrowser/#/R-DME-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Drosophila melanogaster 30616 R-DME-9748999 https://reactome.org/PathwayBrowser/#/R-DME-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Drosophila melanogaster 30616 R-DME-9750546 https://reactome.org/PathwayBrowser/#/R-DME-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Drosophila melanogaster 30616 R-DME-9750656 https://reactome.org/PathwayBrowser/#/R-DME-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Drosophila melanogaster 30616 R-DME-975139 https://reactome.org/PathwayBrowser/#/R-DME-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Drosophila melanogaster 30616 R-DME-9753278 https://reactome.org/PathwayBrowser/#/R-DME-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 30616 R-DME-9753283 https://reactome.org/PathwayBrowser/#/R-DME-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 30616 R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 30616 R-DME-9754974 https://reactome.org/PathwayBrowser/#/R-DME-9754974 ADK phosphorylates RBV IEA Drosophila melanogaster 30616 R-DME-9755013 https://reactome.org/PathwayBrowser/#/R-DME-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Drosophila melanogaster 30616 R-DME-9760094 https://reactome.org/PathwayBrowser/#/R-DME-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Drosophila melanogaster 30616 R-DME-9762094 https://reactome.org/PathwayBrowser/#/R-DME-9762094 GSK3B phosphorylates p-NFE2L2 IEA Drosophila melanogaster 30616 R-DME-9770141 https://reactome.org/PathwayBrowser/#/R-DME-9770141 Formation of the Spliceosomal C* complex IEA Drosophila melanogaster 30616 R-DME-9773803 https://reactome.org/PathwayBrowser/#/R-DME-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Drosophila melanogaster 30616 R-DME-9794120 https://reactome.org/PathwayBrowser/#/R-DME-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Drosophila melanogaster 30616 R-DME-9794572 https://reactome.org/PathwayBrowser/#/R-DME-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Drosophila melanogaster 30616 R-DME-9796053 https://reactome.org/PathwayBrowser/#/R-DME-9796053 PRKCI phosphorylates NFE2L2 IEA Drosophila melanogaster 30616 R-DME-9796067 https://reactome.org/PathwayBrowser/#/R-DME-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Drosophila melanogaster 30616 R-DME-9824977 https://reactome.org/PathwayBrowser/#/R-DME-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Drosophila melanogaster 30616 R-DME-9824994 https://reactome.org/PathwayBrowser/#/R-DME-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Drosophila melanogaster 30616 R-DME-9824995 https://reactome.org/PathwayBrowser/#/R-DME-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Drosophila melanogaster 30616 R-DME-9824999 https://reactome.org/PathwayBrowser/#/R-DME-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Drosophila melanogaster 30616 R-DME-9825759 https://reactome.org/PathwayBrowser/#/R-DME-9825759 MAPK-dependent phosphorylation of KARS IEA Drosophila melanogaster 30616 R-DME-983140 https://reactome.org/PathwayBrowser/#/R-DME-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Drosophila melanogaster 30616 R-DME-983153 https://reactome.org/PathwayBrowser/#/R-DME-983153 E1 mediated ubiquitin activation IEA Drosophila melanogaster 30616 R-DME-983156 https://reactome.org/PathwayBrowser/#/R-DME-983156 Polyubiquitination of substrate IEA Drosophila melanogaster 30616 R-DME-983259 https://reactome.org/PathwayBrowser/#/R-DME-983259 Kinesins move along microtubules consuming ATP IEA Drosophila melanogaster 30616 R-DME-9833973 https://reactome.org/PathwayBrowser/#/R-DME-9833973 ISGylation of PKR IEA Drosophila melanogaster 30616 R-DME-9836159 https://reactome.org/PathwayBrowser/#/R-DME-9836159 p-PKR dimer phosphorylates DHX9 IEA Drosophila melanogaster 30616 R-DME-9836184 https://reactome.org/PathwayBrowser/#/R-DME-9836184 p-PKR dimer phosphorylates CDK1 IEA Drosophila melanogaster 30616 R-DME-9836322 https://reactome.org/PathwayBrowser/#/R-DME-9836322 p-PKR dimer phosphorylates MKK6 IEA Drosophila melanogaster 30616 R-DME-9836362 https://reactome.org/PathwayBrowser/#/R-DME-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Drosophila melanogaster 30616 R-DME-9836383 https://reactome.org/PathwayBrowser/#/R-DME-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Drosophila melanogaster 30616 R-DME-9836515 https://reactome.org/PathwayBrowser/#/R-DME-9836515 p-PKR dimer phosphorylates PTPN2 IEA Drosophila melanogaster 30616 R-DME-9836617 https://reactome.org/PathwayBrowser/#/R-DME-9836617 p-PKR dimer phosphorylates SPHK1 IEA Drosophila melanogaster 30616 R-DME-9836664 https://reactome.org/PathwayBrowser/#/R-DME-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Drosophila melanogaster 30616 R-DME-9837337 https://reactome.org/PathwayBrowser/#/R-DME-9837337 DCAKD phosphorylates DP-CoA IEA Drosophila melanogaster 30616 R-DME-9838004 https://reactome.org/PathwayBrowser/#/R-DME-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Drosophila melanogaster 30616 R-DME-9838081 https://reactome.org/PathwayBrowser/#/R-DME-9838081 LONP1 degrades mitochondrial matrix proteins IEA Drosophila melanogaster 30616 R-DME-9838289 https://reactome.org/PathwayBrowser/#/R-DME-9838289 CLPXP degrades mitochondrial matrix proteins IEA Drosophila melanogaster 30616 R-DME-9838321 https://reactome.org/PathwayBrowser/#/R-DME-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Drosophila melanogaster 30616 R-DME-9839059 https://reactome.org/PathwayBrowser/#/R-DME-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Drosophila melanogaster 30616 R-DME-9839105 https://reactome.org/PathwayBrowser/#/R-DME-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Drosophila melanogaster 30616 R-DME-9839113 https://reactome.org/PathwayBrowser/#/R-DME-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Drosophila melanogaster 30616 R-DME-9843721 https://reactome.org/PathwayBrowser/#/R-DME-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Drosophila melanogaster 30616 R-DRE-109624 https://reactome.org/PathwayBrowser/#/R-DRE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Danio rerio 30616 R-DRE-109671 https://reactome.org/PathwayBrowser/#/R-DRE-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Danio rerio 30616 R-DRE-109702 https://reactome.org/PathwayBrowser/#/R-DRE-109702 PDPK1 phosphorylates AKT2 IEA Danio rerio 30616 R-DRE-109860 https://reactome.org/PathwayBrowser/#/R-DRE-109860 MAP2K1 phosphorylates MAPK3 IEA Danio rerio 30616 R-DRE-109862 https://reactome.org/PathwayBrowser/#/R-DRE-109862 MAP2K2 phosphorylates MAPK1 IEA Danio rerio 30616 R-DRE-109903 https://reactome.org/PathwayBrowser/#/R-DRE-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Danio rerio 30616 R-DRE-110133 https://reactome.org/PathwayBrowser/#/R-DRE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Danio rerio 30616 R-DRE-110137 https://reactome.org/PathwayBrowser/#/R-DRE-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Danio rerio 30616 R-DRE-110138 https://reactome.org/PathwayBrowser/#/R-DRE-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 30616 R-DRE-110144 https://reactome.org/PathwayBrowser/#/R-DRE-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Danio rerio 30616 R-DRE-110145 https://reactome.org/PathwayBrowser/#/R-DRE-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Danio rerio 30616 R-DRE-1112510 https://reactome.org/PathwayBrowser/#/R-DRE-1112510 IL6ST is tyrosine phosphorylated IEA Danio rerio 30616 R-DRE-1112514 https://reactome.org/PathwayBrowser/#/R-DRE-1112514 JAK activation IEA Danio rerio 30616 R-DRE-1112602 https://reactome.org/PathwayBrowser/#/R-DRE-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Danio rerio 30616 R-DRE-1112703 https://reactome.org/PathwayBrowser/#/R-DRE-1112703 PTPN11 is phosphorylated IEA Danio rerio 30616 R-DRE-1112727 https://reactome.org/PathwayBrowser/#/R-DRE-1112727 Serine phosphorylation of STATs IEA Danio rerio 30616 R-DRE-111742 https://reactome.org/PathwayBrowser/#/R-DRE-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 30616 R-DRE-111751 https://reactome.org/PathwayBrowser/#/R-DRE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 30616 R-DRE-111804 https://reactome.org/PathwayBrowser/#/R-DRE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 30616 R-DRE-111898 https://reactome.org/PathwayBrowser/#/R-DRE-111898 Phosphorylation of cPLA2 by ERK-2 IEA Danio rerio 30616 R-DRE-111930 https://reactome.org/PathwayBrowser/#/R-DRE-111930 Adenylate cyclase produces cAMP IEA Danio rerio 30616 R-DRE-112342 https://reactome.org/PathwayBrowser/#/R-DRE-112342 Inactivation of MAP2K1 by CDK1 IEA Danio rerio 30616 R-DRE-114252 https://reactome.org/PathwayBrowser/#/R-DRE-114252 Cleavage of Procaspase-3 by the apoptosome IEA Danio rerio 30616 R-DRE-114254 https://reactome.org/PathwayBrowser/#/R-DRE-114254 CYCS binds to APAF1 IEA Danio rerio 30616 R-DRE-114256 https://reactome.org/PathwayBrowser/#/R-DRE-114256 CYCS:APAF1 binds procaspase-9 IEA Danio rerio 30616 R-DRE-114261 https://reactome.org/PathwayBrowser/#/R-DRE-114261 Cleavage of Procaspase-7 by the apoptosome IEA Danio rerio 30616 R-DRE-114684 https://reactome.org/PathwayBrowser/#/R-DRE-114684 Phosphorylation of Syntaxin-4 IEA Danio rerio 30616 R-DRE-1168459 https://reactome.org/PathwayBrowser/#/R-DRE-1168459 Lyn activates ERK IEA Danio rerio 30616 R-DRE-1181149 https://reactome.org/PathwayBrowser/#/R-DRE-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Danio rerio 30616 R-DRE-1247935 https://reactome.org/PathwayBrowser/#/R-DRE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Danio rerio 30616 R-DRE-1247960 https://reactome.org/PathwayBrowser/#/R-DRE-1247960 Activation of p38 MAPK IEA Danio rerio 30616 R-DRE-1250195 https://reactome.org/PathwayBrowser/#/R-DRE-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Danio rerio 30616 R-DRE-1250315 https://reactome.org/PathwayBrowser/#/R-DRE-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Danio rerio 30616 R-DRE-1250370 https://reactome.org/PathwayBrowser/#/R-DRE-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Danio rerio 30616 R-DRE-1250462 https://reactome.org/PathwayBrowser/#/R-DRE-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Danio rerio 30616 R-DRE-1295609 https://reactome.org/PathwayBrowser/#/R-DRE-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Danio rerio 30616 R-DRE-1306979 https://reactome.org/PathwayBrowser/#/R-DRE-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Danio rerio 30616 R-DRE-1362270 https://reactome.org/PathwayBrowser/#/R-DRE-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Danio rerio 30616 R-DRE-139855 https://reactome.org/PathwayBrowser/#/R-DRE-139855 P2X1-mediated entry of Ca++ from plasma IEA Danio rerio 30616 R-DRE-1433418 https://reactome.org/PathwayBrowser/#/R-DRE-1433418 Phosphorylation of JAK2 IEA Danio rerio 30616 R-DRE-1433488 https://reactome.org/PathwayBrowser/#/R-DRE-1433488 Phosphorylation of SHP2 by SFKs IEA Danio rerio 30616 R-DRE-1433506 https://reactome.org/PathwayBrowser/#/R-DRE-1433506 Phosphorylation of APS IEA Danio rerio 30616 R-DRE-1433514 https://reactome.org/PathwayBrowser/#/R-DRE-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Danio rerio 30616 R-DRE-1454916 https://reactome.org/PathwayBrowser/#/R-DRE-1454916 The ABCC family mediates organic anion transport IEA Danio rerio 30616 R-DRE-1454928 https://reactome.org/PathwayBrowser/#/R-DRE-1454928 ABCG4 may mediate cholesterol efflux IEA Danio rerio 30616 R-DRE-1470009 https://reactome.org/PathwayBrowser/#/R-DRE-1470009 Phosphorylation of STATs IEA Danio rerio 30616 R-DRE-1472121 https://reactome.org/PathwayBrowser/#/R-DRE-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Danio rerio 30616 R-DRE-1483004 https://reactome.org/PathwayBrowser/#/R-DRE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Danio rerio 30616 R-DRE-1483222 https://reactome.org/PathwayBrowser/#/R-DRE-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Danio rerio 30616 R-DRE-1524186 https://reactome.org/PathwayBrowser/#/R-DRE-1524186 Phosphorylation of PLCgamma by PDGFR IEA Danio rerio 30616 R-DRE-1549526 https://reactome.org/PathwayBrowser/#/R-DRE-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Danio rerio 30616 R-DRE-156682 https://reactome.org/PathwayBrowser/#/R-DRE-156682 PLK1 phosphorylates NUDC IEA Danio rerio 30616 R-DRE-156699 https://reactome.org/PathwayBrowser/#/R-DRE-156699 Inactivation of Wee1 kinase IEA Danio rerio 30616 R-DRE-156723 https://reactome.org/PathwayBrowser/#/R-DRE-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Danio rerio 30616 R-DRE-159425 https://reactome.org/PathwayBrowser/#/R-DRE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 30616 R-DRE-159443 https://reactome.org/PathwayBrowser/#/R-DRE-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Danio rerio 30616 R-DRE-159567 https://reactome.org/PathwayBrowser/#/R-DRE-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Danio rerio 30616 R-DRE-162657 https://reactome.org/PathwayBrowser/#/R-DRE-162657 Inactivation of Myt1 kinase IEA Danio rerio 30616 R-DRE-163010 https://reactome.org/PathwayBrowser/#/R-DRE-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Danio rerio 30616 R-DRE-163215 https://reactome.org/PathwayBrowser/#/R-DRE-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Danio rerio 30616 R-DRE-164832 https://reactome.org/PathwayBrowser/#/R-DRE-164832 ATPase synthesizes ATP IEA Danio rerio 30616 R-DRE-164834 https://reactome.org/PathwayBrowser/#/R-DRE-164834 Enzyme-bound ATP is released IEA Danio rerio 30616 R-DRE-165692 https://reactome.org/PathwayBrowser/#/R-DRE-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Danio rerio 30616 R-DRE-165718 https://reactome.org/PathwayBrowser/#/R-DRE-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Danio rerio 30616 R-DRE-165726 https://reactome.org/PathwayBrowser/#/R-DRE-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Danio rerio 30616 R-DRE-1675773 https://reactome.org/PathwayBrowser/#/R-DRE-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Danio rerio 30616 R-DRE-1675776 https://reactome.org/PathwayBrowser/#/R-DRE-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Danio rerio 30616 R-DRE-1675780 https://reactome.org/PathwayBrowser/#/R-DRE-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Danio rerio 30616 R-DRE-1675810 https://reactome.org/PathwayBrowser/#/R-DRE-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Danio rerio 30616 R-DRE-1675813 https://reactome.org/PathwayBrowser/#/R-DRE-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Danio rerio 30616 R-DRE-1675883 https://reactome.org/PathwayBrowser/#/R-DRE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Danio rerio 30616 R-DRE-1675974 https://reactome.org/PathwayBrowser/#/R-DRE-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Danio rerio 30616 R-DRE-1676048 https://reactome.org/PathwayBrowser/#/R-DRE-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Danio rerio 30616 R-DRE-1676082 https://reactome.org/PathwayBrowser/#/R-DRE-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Danio rerio 30616 R-DRE-1676109 https://reactome.org/PathwayBrowser/#/R-DRE-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Danio rerio 30616 R-DRE-1676134 https://reactome.org/PathwayBrowser/#/R-DRE-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Danio rerio 30616 R-DRE-1676145 https://reactome.org/PathwayBrowser/#/R-DRE-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Danio rerio 30616 R-DRE-1676185 https://reactome.org/PathwayBrowser/#/R-DRE-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Danio rerio 30616 R-DRE-168136 https://reactome.org/PathwayBrowser/#/R-DRE-168136 Activated JNKs phosphorylate c-JUN IEA Danio rerio 30616 R-DRE-168162 https://reactome.org/PathwayBrowser/#/R-DRE-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Danio rerio 30616 R-DRE-169905 https://reactome.org/PathwayBrowser/#/R-DRE-169905 ARMS is phosphorylated by active TrkA receptor IEA Danio rerio 30616 R-DRE-170026 https://reactome.org/PathwayBrowser/#/R-DRE-170026 Protons are translocated from the intermembrane space to the matrix IEA Danio rerio 30616 R-DRE-170055 https://reactome.org/PathwayBrowser/#/R-DRE-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Danio rerio 30616 R-DRE-170070 https://reactome.org/PathwayBrowser/#/R-DRE-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Danio rerio 30616 R-DRE-170126 https://reactome.org/PathwayBrowser/#/R-DRE-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Danio rerio 30616 R-DRE-170676 https://reactome.org/PathwayBrowser/#/R-DRE-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Danio rerio 30616 R-DRE-170843 https://reactome.org/PathwayBrowser/#/R-DRE-170843 TGFBR2 phosphorylates TGFBR1 IEA Danio rerio 30616 R-DRE-170868 https://reactome.org/PathwayBrowser/#/R-DRE-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Danio rerio 30616 R-DRE-174122 https://reactome.org/PathwayBrowser/#/R-DRE-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Danio rerio 30616 R-DRE-174164 https://reactome.org/PathwayBrowser/#/R-DRE-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Danio rerio 30616 R-DRE-174174 https://reactome.org/PathwayBrowser/#/R-DRE-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Danio rerio 30616 R-DRE-174251 https://reactome.org/PathwayBrowser/#/R-DRE-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Danio rerio 30616 R-DRE-174389 https://reactome.org/PathwayBrowser/#/R-DRE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Danio rerio 30616 R-DRE-174391 https://reactome.org/PathwayBrowser/#/R-DRE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Danio rerio 30616 R-DRE-174392 https://reactome.org/PathwayBrowser/#/R-DRE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Danio rerio 30616 R-DRE-174394 https://reactome.org/PathwayBrowser/#/R-DRE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Danio rerio 30616 R-DRE-177157 https://reactome.org/PathwayBrowser/#/R-DRE-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Danio rerio 30616 R-DRE-177930 https://reactome.org/PathwayBrowser/#/R-DRE-177930 GAB1 phosphorylation by EGFR kinase IEA Danio rerio 30616 R-DRE-177934 https://reactome.org/PathwayBrowser/#/R-DRE-177934 EGFR autophosphorylation IEA Danio rerio 30616 R-DRE-177937 https://reactome.org/PathwayBrowser/#/R-DRE-177937 Phosphorylation of EGFR by SRC kinase IEA Danio rerio 30616 R-DRE-177939 https://reactome.org/PathwayBrowser/#/R-DRE-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Danio rerio 30616 R-DRE-182969 https://reactome.org/PathwayBrowser/#/R-DRE-182969 Phosphorylation of CBL (EGFR:CBL) IEA Danio rerio 30616 R-DRE-183058 https://reactome.org/PathwayBrowser/#/R-DRE-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Danio rerio 30616 R-DRE-1855157 https://reactome.org/PathwayBrowser/#/R-DRE-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Danio rerio 30616 R-DRE-1855158 https://reactome.org/PathwayBrowser/#/R-DRE-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Danio rerio 30616 R-DRE-1855162 https://reactome.org/PathwayBrowser/#/R-DRE-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Danio rerio 30616 R-DRE-1855169 https://reactome.org/PathwayBrowser/#/R-DRE-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Danio rerio 30616 R-DRE-1855172 https://reactome.org/PathwayBrowser/#/R-DRE-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Danio rerio 30616 R-DRE-1855176 https://reactome.org/PathwayBrowser/#/R-DRE-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Danio rerio 30616 R-DRE-1855179 https://reactome.org/PathwayBrowser/#/R-DRE-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Danio rerio 30616 R-DRE-1855181 https://reactome.org/PathwayBrowser/#/R-DRE-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Danio rerio 30616 R-DRE-1855185 https://reactome.org/PathwayBrowser/#/R-DRE-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 30616 R-DRE-1855193 https://reactome.org/PathwayBrowser/#/R-DRE-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Danio rerio 30616 R-DRE-1855194 https://reactome.org/PathwayBrowser/#/R-DRE-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Danio rerio 30616 R-DRE-1855197 https://reactome.org/PathwayBrowser/#/R-DRE-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Danio rerio 30616 R-DRE-1855206 https://reactome.org/PathwayBrowser/#/R-DRE-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 30616 R-DRE-1855207 https://reactome.org/PathwayBrowser/#/R-DRE-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Danio rerio 30616 R-DRE-1855223 https://reactome.org/PathwayBrowser/#/R-DRE-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Danio rerio 30616 R-DRE-1855224 https://reactome.org/PathwayBrowser/#/R-DRE-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Danio rerio 30616 R-DRE-1855227 https://reactome.org/PathwayBrowser/#/R-DRE-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Danio rerio 30616 R-DRE-1855228 https://reactome.org/PathwayBrowser/#/R-DRE-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 30616 R-DRE-1855230 https://reactome.org/PathwayBrowser/#/R-DRE-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Danio rerio 30616 R-DRE-1855233 https://reactome.org/PathwayBrowser/#/R-DRE-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Danio rerio 30616 R-DRE-186800 https://reactome.org/PathwayBrowser/#/R-DRE-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Danio rerio 30616 R-DRE-187520 https://reactome.org/PathwayBrowser/#/R-DRE-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Danio rerio 30616 R-DRE-187688 https://reactome.org/PathwayBrowser/#/R-DRE-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Danio rerio 30616 R-DRE-187916 https://reactome.org/PathwayBrowser/#/R-DRE-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Danio rerio 30616 R-DRE-187948 https://reactome.org/PathwayBrowser/#/R-DRE-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Danio rerio 30616 R-DRE-188390 https://reactome.org/PathwayBrowser/#/R-DRE-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Danio rerio 30616 R-DRE-190326 https://reactome.org/PathwayBrowser/#/R-DRE-190326 Autocatalytic phosphorylation of FGFR4 IEA Danio rerio 30616 R-DRE-190385 https://reactome.org/PathwayBrowser/#/R-DRE-190385 Autocatalytic phosphorylation of FGFR3b IEA Danio rerio 30616 R-DRE-190388 https://reactome.org/PathwayBrowser/#/R-DRE-190388 Autocatalytic phosphorylation of FGFR3c IEA Danio rerio 30616 R-DRE-190408 https://reactome.org/PathwayBrowser/#/R-DRE-190408 Autocatalytic phosphorylation of FGFR2b IEA Danio rerio 30616 R-DRE-190413 https://reactome.org/PathwayBrowser/#/R-DRE-190413 Autocatalytic phosphorylation of FGFR2c IEA Danio rerio 30616 R-DRE-190427 https://reactome.org/PathwayBrowser/#/R-DRE-190427 Autocatalytic phosphorylation of FGFR1b IEA Danio rerio 30616 R-DRE-190429 https://reactome.org/PathwayBrowser/#/R-DRE-190429 Autocatalytic phosphorylation of FGFR1c IEA Danio rerio 30616 R-DRE-191062 https://reactome.org/PathwayBrowser/#/R-DRE-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Danio rerio 30616 R-DRE-191380 https://reactome.org/PathwayBrowser/#/R-DRE-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Danio rerio 30616 R-DRE-191414 https://reactome.org/PathwayBrowser/#/R-DRE-191414 MVD decarboxylates MVA5PP to IPPP IEA Danio rerio 30616 R-DRE-191422 https://reactome.org/PathwayBrowser/#/R-DRE-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Danio rerio 30616 R-DRE-192137 https://reactome.org/PathwayBrowser/#/R-DRE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 30616 R-DRE-193407 https://reactome.org/PathwayBrowser/#/R-DRE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 30616 R-DRE-193711 https://reactome.org/PathwayBrowser/#/R-DRE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 30616 R-DRE-193766 https://reactome.org/PathwayBrowser/#/R-DRE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 30616 R-DRE-1963581 https://reactome.org/PathwayBrowser/#/R-DRE-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Danio rerio 30616 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 30616 R-DRE-1963586 https://reactome.org/PathwayBrowser/#/R-DRE-1963586 SRC family kinases phosphorylate ERBB2 IEA Danio rerio 30616 R-DRE-196753 https://reactome.org/PathwayBrowser/#/R-DRE-196753 2xPPCS ligates PPanK with Cys IEA Danio rerio 30616 R-DRE-196754 https://reactome.org/PathwayBrowser/#/R-DRE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Danio rerio 30616 R-DRE-196761 https://reactome.org/PathwayBrowser/#/R-DRE-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Danio rerio 30616 R-DRE-196773 https://reactome.org/PathwayBrowser/#/R-DRE-196773 COASY phosphorylates DP-CoA IEA Danio rerio 30616 R-DRE-196929 https://reactome.org/PathwayBrowser/#/R-DRE-196929 FLAD1 phosphorylates FMN IEA Danio rerio 30616 R-DRE-197198 https://reactome.org/PathwayBrowser/#/R-DRE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Danio rerio 30616 R-DRE-197235 https://reactome.org/PathwayBrowser/#/R-DRE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 30616 R-DRE-197271 https://reactome.org/PathwayBrowser/#/R-DRE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Danio rerio 30616 R-DRE-197958 https://reactome.org/PathwayBrowser/#/R-DRE-197958 FPGS-2 transforms THF to THFPG IEA Danio rerio 30616 R-DRE-198314 https://reactome.org/PathwayBrowser/#/R-DRE-198314 DAG stimulates protein kinase C-delta IEA Danio rerio 30616 R-DRE-198599 https://reactome.org/PathwayBrowser/#/R-DRE-198599 AKT phosphorylates MDM2 IEA Danio rerio 30616 R-DRE-198611 https://reactome.org/PathwayBrowser/#/R-DRE-198611 AKT phosphorylates IKKalpha IEA Danio rerio 30616 R-DRE-198613 https://reactome.org/PathwayBrowser/#/R-DRE-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Danio rerio 30616 R-DRE-198621 https://reactome.org/PathwayBrowser/#/R-DRE-198621 AKT phosphorylates caspase-9 IEA Danio rerio 30616 R-DRE-199203 https://reactome.org/PathwayBrowser/#/R-DRE-199203 PANK1/3 phosphorylate PanK IEA Danio rerio 30616 R-DRE-199298 https://reactome.org/PathwayBrowser/#/R-DRE-199298 AKT phosphorylates CREB1 IEA Danio rerio 30616 R-DRE-199299 https://reactome.org/PathwayBrowser/#/R-DRE-199299 AKT phosphorylates FOXO transcription factors IEA Danio rerio 30616 R-DRE-199863 https://reactome.org/PathwayBrowser/#/R-DRE-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Danio rerio 30616 R-DRE-199917 https://reactome.org/PathwayBrowser/#/R-DRE-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Danio rerio 30616 R-DRE-200318 https://reactome.org/PathwayBrowser/#/R-DRE-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Danio rerio 30616 R-DRE-200326 https://reactome.org/PathwayBrowser/#/R-DRE-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Danio rerio 30616 R-DRE-200512 https://reactome.org/PathwayBrowser/#/R-DRE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 30616 R-DRE-200681 https://reactome.org/PathwayBrowser/#/R-DRE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Danio rerio 30616 R-DRE-200682 https://reactome.org/PathwayBrowser/#/R-DRE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Danio rerio 30616 R-DRE-200711 https://reactome.org/PathwayBrowser/#/R-DRE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Danio rerio 30616 R-DRE-201035 https://reactome.org/PathwayBrowser/#/R-DRE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Danio rerio 30616 R-DRE-201443 https://reactome.org/PathwayBrowser/#/R-DRE-201443 Type II receptor phosphorylates type I receptor IEA Danio rerio 30616 R-DRE-201476 https://reactome.org/PathwayBrowser/#/R-DRE-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Danio rerio 30616 R-DRE-201510 https://reactome.org/PathwayBrowser/#/R-DRE-201510 PI3K synthesizes PIP3 downstream of ALK IEA Danio rerio 30616 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 30616 R-DRE-201677 https://reactome.org/PathwayBrowser/#/R-DRE-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Danio rerio 30616 R-DRE-2028583 https://reactome.org/PathwayBrowser/#/R-DRE-2028583 Phosphorylation of YAP by LATS2 IEA Danio rerio 30616 R-DRE-2028589 https://reactome.org/PathwayBrowser/#/R-DRE-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Danio rerio 30616 R-DRE-2028591 https://reactome.org/PathwayBrowser/#/R-DRE-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Danio rerio 30616 R-DRE-2028598 https://reactome.org/PathwayBrowser/#/R-DRE-2028598 Phosphorylation of YAP by LATS1 IEA Danio rerio 30616 R-DRE-2028635 https://reactome.org/PathwayBrowser/#/R-DRE-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Danio rerio 30616 R-DRE-2028661 https://reactome.org/PathwayBrowser/#/R-DRE-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Danio rerio 30616 R-DRE-2028673 https://reactome.org/PathwayBrowser/#/R-DRE-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Danio rerio 30616 R-DRE-2028675 https://reactome.org/PathwayBrowser/#/R-DRE-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Danio rerio 30616 R-DRE-2029466 https://reactome.org/PathwayBrowser/#/R-DRE-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Danio rerio 30616 R-DRE-2029473 https://reactome.org/PathwayBrowser/#/R-DRE-2029473 Branching and elongation of mother and daughter filaments IEA Danio rerio 30616 R-DRE-203070 https://reactome.org/PathwayBrowser/#/R-DRE-203070 Association of profilin with monomeric actin IEA Danio rerio 30616 R-DRE-2046085 https://reactome.org/PathwayBrowser/#/R-DRE-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Danio rerio 30616 R-DRE-2046098 https://reactome.org/PathwayBrowser/#/R-DRE-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Danio rerio 30616 R-DRE-205136 https://reactome.org/PathwayBrowser/#/R-DRE-205136 GTP-bound RAC contributes to JNK activation IEA Danio rerio 30616 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 30616 R-DRE-2060328 https://reactome.org/PathwayBrowser/#/R-DRE-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Danio rerio 30616 R-DRE-211164 https://reactome.org/PathwayBrowser/#/R-DRE-211164 AKT phosphorylates FOXO1A IEA Danio rerio 30616 R-DRE-212710 https://reactome.org/PathwayBrowser/#/R-DRE-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Danio rerio 30616 R-DRE-216723 https://reactome.org/PathwayBrowser/#/R-DRE-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Danio rerio 30616 R-DRE-216757 https://reactome.org/PathwayBrowser/#/R-DRE-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Danio rerio 30616 R-DRE-2168079 https://reactome.org/PathwayBrowser/#/R-DRE-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Danio rerio 30616 R-DRE-2197690 https://reactome.org/PathwayBrowser/#/R-DRE-2197690 Detachment of WASP/WAVE IEA Danio rerio 30616 R-DRE-2245218 https://reactome.org/PathwayBrowser/#/R-DRE-2245218 CDK1 phosphorylates PHF8 IEA Danio rerio 30616 R-DRE-2267372 https://reactome.org/PathwayBrowser/#/R-DRE-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Danio rerio 30616 R-DRE-2294580 https://reactome.org/PathwayBrowser/#/R-DRE-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Danio rerio 30616 R-DRE-2294600 https://reactome.org/PathwayBrowser/#/R-DRE-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Danio rerio 30616 R-DRE-2316434 https://reactome.org/PathwayBrowser/#/R-DRE-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 30616 R-DRE-2408551 https://reactome.org/PathwayBrowser/#/R-DRE-2408551 SeMet is converted to AdoSeMet by MAT IEA Danio rerio 30616 R-DRE-2422927 https://reactome.org/PathwayBrowser/#/R-DRE-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Danio rerio 30616 R-DRE-2430535 https://reactome.org/PathwayBrowser/#/R-DRE-2430535 MASTL phosphorylates ENSA IEA Danio rerio 30616 R-DRE-2466068 https://reactome.org/PathwayBrowser/#/R-DRE-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Danio rerio 30616 R-DRE-2468293 https://reactome.org/PathwayBrowser/#/R-DRE-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Danio rerio 30616 R-DRE-2562526 https://reactome.org/PathwayBrowser/#/R-DRE-2562526 PLK1 phosphorylates OPTN IEA Danio rerio 30616 R-DRE-2581474 https://reactome.org/PathwayBrowser/#/R-DRE-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Danio rerio 30616 R-DRE-266082 https://reactome.org/PathwayBrowser/#/R-DRE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Danio rerio 30616 R-DRE-2990833 https://reactome.org/PathwayBrowser/#/R-DRE-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Danio rerio 30616 R-DRE-3000327 https://reactome.org/PathwayBrowser/#/R-DRE-3000327 PLK1 phosphorylates BORA IEA Danio rerio 30616 R-DRE-3132737 https://reactome.org/PathwayBrowser/#/R-DRE-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Danio rerio 30616 R-DRE-3229102 https://reactome.org/PathwayBrowser/#/R-DRE-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Danio rerio 30616 R-DRE-3238999 https://reactome.org/PathwayBrowser/#/R-DRE-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Danio rerio 30616 R-DRE-3239014 https://reactome.org/PathwayBrowser/#/R-DRE-3239014 MAPKAPK5 phosphorylates TP53 IEA Danio rerio 30616 R-DRE-3239019 https://reactome.org/PathwayBrowser/#/R-DRE-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Danio rerio 30616 R-DRE-3249371 https://reactome.org/PathwayBrowser/#/R-DRE-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Danio rerio 30616 R-DRE-3249379 https://reactome.org/PathwayBrowser/#/R-DRE-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Danio rerio 30616 R-DRE-3249390 https://reactome.org/PathwayBrowser/#/R-DRE-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Danio rerio 30616 R-DRE-3371422 https://reactome.org/PathwayBrowser/#/R-DRE-3371422 ATP hydrolysis by HSP70 IEA Danio rerio 30616 R-DRE-3371590 https://reactome.org/PathwayBrowser/#/R-DRE-3371590 HSP70 binds to HSP40:nascent protein IEA Danio rerio 30616 R-DRE-373747 https://reactome.org/PathwayBrowser/#/R-DRE-373747 Phosphorylation of nephrin by FYN IEA Danio rerio 30616 R-DRE-374701 https://reactome.org/PathwayBrowser/#/R-DRE-374701 Phosphorylation of DCC by Fyn IEA Danio rerio 30616 R-DRE-3769394 https://reactome.org/PathwayBrowser/#/R-DRE-3769394 AKT phosphorylates CBY1 IEA Danio rerio 30616 R-DRE-377186 https://reactome.org/PathwayBrowser/#/R-DRE-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Danio rerio 30616 R-DRE-3772435 https://reactome.org/PathwayBrowser/#/R-DRE-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Danio rerio 30616 R-DRE-377640 https://reactome.org/PathwayBrowser/#/R-DRE-377640 Autophosphorylation of SRC IEA Danio rerio 30616 R-DRE-380780 https://reactome.org/PathwayBrowser/#/R-DRE-380780 Activation of Src IEA Danio rerio 30616 R-DRE-382560 https://reactome.org/PathwayBrowser/#/R-DRE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Danio rerio 30616 R-DRE-382575 https://reactome.org/PathwayBrowser/#/R-DRE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Danio rerio 30616 R-DRE-383190 https://reactome.org/PathwayBrowser/#/R-DRE-383190 HCO3- transport through ion channel IEA Danio rerio 30616 R-DRE-3857329 https://reactome.org/PathwayBrowser/#/R-DRE-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Danio rerio 30616 R-DRE-389083 https://reactome.org/PathwayBrowser/#/R-DRE-389083 Autophosphorylation of PDGF alpha receptors IEA Danio rerio 30616 R-DRE-389086 https://reactome.org/PathwayBrowser/#/R-DRE-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Danio rerio 30616 R-DRE-3928578 https://reactome.org/PathwayBrowser/#/R-DRE-3928578 EPH receptors autophosphorylate IEA Danio rerio 30616 R-DRE-3928595 https://reactome.org/PathwayBrowser/#/R-DRE-3928595 N-WASP binds ARP2/3 and G-actin IEA Danio rerio 30616 R-DRE-3928604 https://reactome.org/PathwayBrowser/#/R-DRE-3928604 SFKs phosphorylate VAV2,3 IEA Danio rerio 30616 R-DRE-399939 https://reactome.org/PathwayBrowser/#/R-DRE-399939 Autophosphorylation of PAK IEA Danio rerio 30616 R-DRE-399944 https://reactome.org/PathwayBrowser/#/R-DRE-399944 Phosphorylation of CRMPs by Cdk5 IEA Danio rerio 30616 R-DRE-399952 https://reactome.org/PathwayBrowser/#/R-DRE-399952 Phosphorylation of LIMK-1 by PAK IEA Danio rerio 30616 R-DRE-4085028 https://reactome.org/PathwayBrowser/#/R-DRE-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Danio rerio 30616 R-DRE-4086410 https://reactome.org/PathwayBrowser/#/R-DRE-4086410 CDK1 phosphorylates BORA IEA Danio rerio 30616 R-DRE-4088024 https://reactome.org/PathwayBrowser/#/R-DRE-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Danio rerio 30616 R-DRE-4088134 https://reactome.org/PathwayBrowser/#/R-DRE-4088134 PLK1 phosphorylates FOXM1 IEA Danio rerio 30616 R-DRE-4093332 https://reactome.org/PathwayBrowser/#/R-DRE-4093332 p-EPHB phosphorylates SDC2 IEA Danio rerio 30616 R-DRE-419490 https://reactome.org/PathwayBrowser/#/R-DRE-419490 Binding of ATP to P2X receptors IEA Danio rerio 30616 R-DRE-419644 https://reactome.org/PathwayBrowser/#/R-DRE-419644 Transphosphorylation of pLIMK1 IEA Danio rerio 30616 R-DRE-428941 https://reactome.org/PathwayBrowser/#/R-DRE-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Danio rerio 30616 R-DRE-428961 https://reactome.org/PathwayBrowser/#/R-DRE-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Danio rerio 30616 R-DRE-429016 https://reactome.org/PathwayBrowser/#/R-DRE-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Danio rerio 30616 R-DRE-429157 https://reactome.org/PathwayBrowser/#/R-DRE-429157 ABCC4 accumulation of dense granule contents IEA Danio rerio 30616 R-DRE-429698 https://reactome.org/PathwayBrowser/#/R-DRE-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Danio rerio 30616 R-DRE-429714 https://reactome.org/PathwayBrowser/#/R-DRE-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Danio rerio 30616 R-DRE-432148 https://reactome.org/PathwayBrowser/#/R-DRE-432148 Fgr may phosphorylate p38 MAPK IEA Danio rerio 30616 R-DRE-432232 https://reactome.org/PathwayBrowser/#/R-DRE-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Danio rerio 30616 R-DRE-434382 https://reactome.org/PathwayBrowser/#/R-DRE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Danio rerio 30616 R-DRE-437162 https://reactome.org/PathwayBrowser/#/R-DRE-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Danio rerio 30616 R-DRE-4420117 https://reactome.org/PathwayBrowser/#/R-DRE-4420117 VEGFR2 autophosphorylates IEA Danio rerio 30616 R-DRE-4420121 https://reactome.org/PathwayBrowser/#/R-DRE-4420121 SFKs phosphorylate PLCG1 IEA Danio rerio 30616 R-DRE-4420206 https://reactome.org/PathwayBrowser/#/R-DRE-4420206 Phosphorylation of SRC-1 IEA Danio rerio 30616 R-DRE-447074 https://reactome.org/PathwayBrowser/#/R-DRE-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Danio rerio 30616 R-DRE-448955 https://reactome.org/PathwayBrowser/#/R-DRE-448955 Phosphorylation of MEF2 proteins by p38 IEA Danio rerio 30616 R-DRE-450088 https://reactome.org/PathwayBrowser/#/R-DRE-450088 GLUT1 tetramer binds 4xATP IEA Danio rerio 30616 R-DRE-450092 https://reactome.org/PathwayBrowser/#/R-DRE-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Danio rerio 30616 R-DRE-450222 https://reactome.org/PathwayBrowser/#/R-DRE-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Danio rerio 30616 R-DRE-450325 https://reactome.org/PathwayBrowser/#/R-DRE-450325 c-FOS activation by phospho ERK1/2 IEA Danio rerio 30616 R-DRE-450333 https://reactome.org/PathwayBrowser/#/R-DRE-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Danio rerio 30616 R-DRE-450474 https://reactome.org/PathwayBrowser/#/R-DRE-450474 MK2 phosphorylates BRF1 IEA Danio rerio 30616 R-DRE-450490 https://reactome.org/PathwayBrowser/#/R-DRE-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Danio rerio 30616 R-DRE-450499 https://reactome.org/PathwayBrowser/#/R-DRE-450499 Protein Kinase B (AKT) phosphorylates KSRP IEA Danio rerio 30616 R-DRE-453342 https://reactome.org/PathwayBrowser/#/R-DRE-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Danio rerio 30616 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 30616 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 30616 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 30616 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 30616 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 30616 R-DRE-504054 https://reactome.org/PathwayBrowser/#/R-DRE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Danio rerio 30616 R-DRE-5218804 https://reactome.org/PathwayBrowser/#/R-DRE-5218804 p38 MAPK activation by VEGFR IEA Danio rerio 30616 R-DRE-5218805 https://reactome.org/PathwayBrowser/#/R-DRE-5218805 PKC autophosphorylates IEA Danio rerio 30616 R-DRE-5218806 https://reactome.org/PathwayBrowser/#/R-DRE-5218806 FYN autophosphorylates IEA Danio rerio 30616 R-DRE-5218812 https://reactome.org/PathwayBrowser/#/R-DRE-5218812 FYN phosphorylates PAK2 IEA Danio rerio 30616 R-DRE-5218814 https://reactome.org/PathwayBrowser/#/R-DRE-5218814 PAK2 autophorylates IEA Danio rerio 30616 R-DRE-5218819 https://reactome.org/PathwayBrowser/#/R-DRE-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 30616 R-DRE-5218821 https://reactome.org/PathwayBrowser/#/R-DRE-5218821 PDK1 phosphorylates PKC IEA Danio rerio 30616 R-DRE-5218854 https://reactome.org/PathwayBrowser/#/R-DRE-5218854 p-Y420-FYN is phosphorylated on S21 IEA Danio rerio 30616 R-DRE-5218916 https://reactome.org/PathwayBrowser/#/R-DRE-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Danio rerio 30616 R-DRE-5223317 https://reactome.org/PathwayBrowser/#/R-DRE-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Danio rerio 30616 R-DRE-5244669 https://reactome.org/PathwayBrowser/#/R-DRE-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Danio rerio 30616 R-DRE-5251942 https://reactome.org/PathwayBrowser/#/R-DRE-5251942 Hikeshi binds HSP70s:ATP IEA Danio rerio 30616 R-DRE-5251955 https://reactome.org/PathwayBrowser/#/R-DRE-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Danio rerio 30616 R-DRE-5251959 https://reactome.org/PathwayBrowser/#/R-DRE-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Danio rerio 30616 R-DRE-5252079 https://reactome.org/PathwayBrowser/#/R-DRE-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Danio rerio 30616 R-DRE-5339524 https://reactome.org/PathwayBrowser/#/R-DRE-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Danio rerio 30616 R-DRE-5357477 https://reactome.org/PathwayBrowser/#/R-DRE-5357477 PAK1-3 phosphorylates VE-cadherin IEA Danio rerio 30616 R-DRE-5358518 https://reactome.org/PathwayBrowser/#/R-DRE-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Danio rerio 30616 R-DRE-5358597 https://reactome.org/PathwayBrowser/#/R-DRE-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Danio rerio 30616 R-DRE-5358599 https://reactome.org/PathwayBrowser/#/R-DRE-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Danio rerio 30616 R-DRE-5358912 https://reactome.org/PathwayBrowser/#/R-DRE-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Danio rerio 30616 R-DRE-5362459 https://reactome.org/PathwayBrowser/#/R-DRE-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Danio rerio 30616 R-DRE-548843 https://reactome.org/PathwayBrowser/#/R-DRE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Danio rerio 30616 R-DRE-5603114 https://reactome.org/PathwayBrowser/#/R-DRE-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Danio rerio 30616 R-DRE-5610720 https://reactome.org/PathwayBrowser/#/R-DRE-5610720 PKA phosphorylates GLI3 IEA Danio rerio 30616 R-DRE-5610722 https://reactome.org/PathwayBrowser/#/R-DRE-5610722 CK1 phosphorylates p-GLI3 IEA Danio rerio 30616 R-DRE-5610727 https://reactome.org/PathwayBrowser/#/R-DRE-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Danio rerio 30616 R-DRE-5617179 https://reactome.org/PathwayBrowser/#/R-DRE-5617179 PRKACA phosphorylates TNNI3 IEA Danio rerio 30616 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 30616 R-DRE-5618099 https://reactome.org/PathwayBrowser/#/R-DRE-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Danio rerio 30616 R-DRE-5618107 https://reactome.org/PathwayBrowser/#/R-DRE-5618107 ATP binding to HSP90 triggers conformation change IEA Danio rerio 30616 R-DRE-5621355 https://reactome.org/PathwayBrowser/#/R-DRE-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Danio rerio 30616 R-DRE-5623667 https://reactome.org/PathwayBrowser/#/R-DRE-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Danio rerio 30616 R-DRE-5625784 https://reactome.org/PathwayBrowser/#/R-DRE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Danio rerio 30616 R-DRE-5626507 https://reactome.org/PathwayBrowser/#/R-DRE-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Danio rerio 30616 R-DRE-5627775 https://reactome.org/PathwayBrowser/#/R-DRE-5627775 Autophosphorylation of PAK1,2,3 IEA Danio rerio 30616 R-DRE-5635842 https://reactome.org/PathwayBrowser/#/R-DRE-5635842 ULK3 phosphorylates GLI IEA Danio rerio 30616 R-DRE-5654147 https://reactome.org/PathwayBrowser/#/R-DRE-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Danio rerio 30616 R-DRE-5654149 https://reactome.org/PathwayBrowser/#/R-DRE-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Danio rerio 30616 R-DRE-5654151 https://reactome.org/PathwayBrowser/#/R-DRE-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Danio rerio 30616 R-DRE-5654222 https://reactome.org/PathwayBrowser/#/R-DRE-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Danio rerio 30616 R-DRE-5654560 https://reactome.org/PathwayBrowser/#/R-DRE-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Danio rerio 30616 R-DRE-5654575 https://reactome.org/PathwayBrowser/#/R-DRE-5654575 Activated FGFR1 phosphorylates FRS2 IEA Danio rerio 30616 R-DRE-5654578 https://reactome.org/PathwayBrowser/#/R-DRE-5654578 Activated FGFR1 phosphorylates FRS3 IEA Danio rerio 30616 R-DRE-5654582 https://reactome.org/PathwayBrowser/#/R-DRE-5654582 Activated FGFR1 phosphorylates SHC1 IEA Danio rerio 30616 R-DRE-5654587 https://reactome.org/PathwayBrowser/#/R-DRE-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Danio rerio 30616 R-DRE-5654605 https://reactome.org/PathwayBrowser/#/R-DRE-5654605 Activated FGFR2 phosphorylates FRS3 IEA Danio rerio 30616 R-DRE-5654607 https://reactome.org/PathwayBrowser/#/R-DRE-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Danio rerio 30616 R-DRE-5654628 https://reactome.org/PathwayBrowser/#/R-DRE-5654628 Activated FGFR3 phosphorylates FRS3 IEA Danio rerio 30616 R-DRE-5654631 https://reactome.org/PathwayBrowser/#/R-DRE-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Danio rerio 30616 R-DRE-5654653 https://reactome.org/PathwayBrowser/#/R-DRE-5654653 Activated FGFR4 phosphorylates FRS3 IEA Danio rerio 30616 R-DRE-5654690 https://reactome.org/PathwayBrowser/#/R-DRE-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 30616 R-DRE-5654989 https://reactome.org/PathwayBrowser/#/R-DRE-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Danio rerio 30616 R-DRE-5662466 https://reactome.org/PathwayBrowser/#/R-DRE-5662466 XYLB phosphorylates D-xylulose IEA Danio rerio 30616 R-DRE-5665802 https://reactome.org/PathwayBrowser/#/R-DRE-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Danio rerio 30616 R-DRE-5665809 https://reactome.org/PathwayBrowser/#/R-DRE-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Danio rerio 30616 R-DRE-5671763 https://reactome.org/PathwayBrowser/#/R-DRE-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Danio rerio 30616 R-DRE-5672010 https://reactome.org/PathwayBrowser/#/R-DRE-5672010 Active MTORC1 phosphorylates ULK1 IEA Danio rerio 30616 R-DRE-5672027 https://reactome.org/PathwayBrowser/#/R-DRE-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Danio rerio 30616 R-DRE-5672828 https://reactome.org/PathwayBrowser/#/R-DRE-5672828 mTORC1 phosphorylates AKT1S1 IEA Danio rerio 30616 R-DRE-5673768 https://reactome.org/PathwayBrowser/#/R-DRE-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Danio rerio 30616 R-DRE-5674130 https://reactome.org/PathwayBrowser/#/R-DRE-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Danio rerio 30616 R-DRE-5674373 https://reactome.org/PathwayBrowser/#/R-DRE-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Danio rerio 30616 R-DRE-5674496 https://reactome.org/PathwayBrowser/#/R-DRE-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Danio rerio 30616 R-DRE-5678863 https://reactome.org/PathwayBrowser/#/R-DRE-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Danio rerio 30616 R-DRE-5679041 https://reactome.org/PathwayBrowser/#/R-DRE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Danio rerio 30616 R-DRE-5682101 https://reactome.org/PathwayBrowser/#/R-DRE-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Danio rerio 30616 R-DRE-5687086 https://reactome.org/PathwayBrowser/#/R-DRE-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Danio rerio 30616 R-DRE-5687088 https://reactome.org/PathwayBrowser/#/R-DRE-5687088 PKA phosphorylates MAPKAPK5 IEA Danio rerio 30616 R-DRE-5687094 https://reactome.org/PathwayBrowser/#/R-DRE-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Danio rerio 30616 R-DRE-5687101 https://reactome.org/PathwayBrowser/#/R-DRE-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Danio rerio 30616 R-DRE-5687121 https://reactome.org/PathwayBrowser/#/R-DRE-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Danio rerio 30616 R-DRE-5690250 https://reactome.org/PathwayBrowser/#/R-DRE-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Danio rerio 30616 R-DRE-5690996 https://reactome.org/PathwayBrowser/#/R-DRE-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Danio rerio 30616 R-DRE-5692480 https://reactome.org/PathwayBrowser/#/R-DRE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Danio rerio 30616 R-DRE-5692755 https://reactome.org/PathwayBrowser/#/R-DRE-5692755 CDK1 phosphorylates MAPK6 IEA Danio rerio 30616 R-DRE-5692775 https://reactome.org/PathwayBrowser/#/R-DRE-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Danio rerio 30616 R-DRE-5692779 https://reactome.org/PathwayBrowser/#/R-DRE-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Danio rerio 30616 R-DRE-5694425 https://reactome.org/PathwayBrowser/#/R-DRE-5694425 NSF ATPase activity dissociates cis-SNARE IEA Danio rerio 30616 R-DRE-5694494 https://reactome.org/PathwayBrowser/#/R-DRE-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Danio rerio 30616 R-DRE-5696004 https://reactome.org/PathwayBrowser/#/R-DRE-5696004 ACSF2 ligates CoA-SH to MCFA IEA Danio rerio 30616 R-DRE-5696074 https://reactome.org/PathwayBrowser/#/R-DRE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Danio rerio 30616 R-DRE-5696839 https://reactome.org/PathwayBrowser/#/R-DRE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Danio rerio 30616 R-DRE-6782131 https://reactome.org/PathwayBrowser/#/R-DRE-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Danio rerio 30616 R-DRE-6784319 https://reactome.org/PathwayBrowser/#/R-DRE-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Danio rerio 30616 R-DRE-6784324 https://reactome.org/PathwayBrowser/#/R-DRE-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Danio rerio 30616 R-DRE-6788798 https://reactome.org/PathwayBrowser/#/R-DRE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 30616 R-DRE-6788810 https://reactome.org/PathwayBrowser/#/R-DRE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 30616 R-DRE-6788855 https://reactome.org/PathwayBrowser/#/R-DRE-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Danio rerio 30616 R-DRE-6788867 https://reactome.org/PathwayBrowser/#/R-DRE-6788867 FN3K phosphorylates ketosamines IEA Danio rerio 30616 R-DRE-6793661 https://reactome.org/PathwayBrowser/#/R-DRE-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Danio rerio 30616 R-DRE-6795460 https://reactome.org/PathwayBrowser/#/R-DRE-6795460 SGK1 phosphorylates MDM2 IEA Danio rerio 30616 R-DRE-6795473 https://reactome.org/PathwayBrowser/#/R-DRE-6795473 PDPK1 phosphorylates SGK1 IEA Danio rerio 30616 R-DRE-6797606 https://reactome.org/PathwayBrowser/#/R-DRE-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Danio rerio 30616 R-DRE-6799495 https://reactome.org/PathwayBrowser/#/R-DRE-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Danio rerio 30616 R-DRE-6801342 https://reactome.org/PathwayBrowser/#/R-DRE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio 30616 R-DRE-6801456 https://reactome.org/PathwayBrowser/#/R-DRE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Danio rerio 30616 R-DRE-6801666 https://reactome.org/PathwayBrowser/#/R-DRE-6801666 PLK2 phosphorylates CENPJ IEA Danio rerio 30616 R-DRE-6803545 https://reactome.org/PathwayBrowser/#/R-DRE-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Danio rerio 30616 R-DRE-6804596 https://reactome.org/PathwayBrowser/#/R-DRE-6804596 APAF1:CYCS binds APIP IEA Danio rerio 30616 R-DRE-6805103 https://reactome.org/PathwayBrowser/#/R-DRE-6805103 AURKA phosphorylates TP53 IEA Danio rerio 30616 R-DRE-6805109 https://reactome.org/PathwayBrowser/#/R-DRE-6805109 CDK2 phosphorylates TP53 IEA Danio rerio 30616 R-DRE-6805276 https://reactome.org/PathwayBrowser/#/R-DRE-6805276 CDK5 phosphorylates TP53 IEA Danio rerio 30616 R-DRE-6805285 https://reactome.org/PathwayBrowser/#/R-DRE-6805285 PLK3 phosphorylates TP53 IEA Danio rerio 30616 R-DRE-6805470 https://reactome.org/PathwayBrowser/#/R-DRE-6805470 AMPK phosphorylates TP53 IEA Danio rerio 30616 R-DRE-6805640 https://reactome.org/PathwayBrowser/#/R-DRE-6805640 AKT phosphorylates KAT6A IEA Danio rerio 30616 R-DRE-6806877 https://reactome.org/PathwayBrowser/#/R-DRE-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Danio rerio 30616 R-DRE-6806967 https://reactome.org/PathwayBrowser/#/R-DRE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Danio rerio 30616 R-DRE-6807868 https://reactome.org/PathwayBrowser/#/R-DRE-6807868 GBF1 stimulates ARF nucleotide exchange IEA Danio rerio 30616 R-DRE-6810233 https://reactome.org/PathwayBrowser/#/R-DRE-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Danio rerio 30616 R-DRE-6811454 https://reactome.org/PathwayBrowser/#/R-DRE-6811454 MAPKs phosphorylate PP2A IEA Danio rerio 30616 R-DRE-6811522 https://reactome.org/PathwayBrowser/#/R-DRE-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Danio rerio 30616 R-DRE-6814120 https://reactome.org/PathwayBrowser/#/R-DRE-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Danio rerio 30616 R-DRE-6814124 https://reactome.org/PathwayBrowser/#/R-DRE-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Danio rerio 30616 R-DRE-6814559 https://reactome.org/PathwayBrowser/#/R-DRE-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Danio rerio 30616 R-DRE-69005 https://reactome.org/PathwayBrowser/#/R-DRE-69005 Cdc6 protein is phosphorylated by CDK IEA Danio rerio 30616 R-DRE-69195 https://reactome.org/PathwayBrowser/#/R-DRE-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Danio rerio 30616 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 30616 R-DRE-70349 https://reactome.org/PathwayBrowser/#/R-DRE-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Danio rerio 30616 R-DRE-70355 https://reactome.org/PathwayBrowser/#/R-DRE-70355 GALK1 phosphorylates Gal to Gal1P IEA Danio rerio 30616 R-DRE-70420 https://reactome.org/PathwayBrowser/#/R-DRE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Danio rerio 30616 R-DRE-70467 https://reactome.org/PathwayBrowser/#/R-DRE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Danio rerio 30616 R-DRE-70486 https://reactome.org/PathwayBrowser/#/R-DRE-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Danio rerio 30616 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 30616 R-DRE-70606 https://reactome.org/PathwayBrowser/#/R-DRE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Danio rerio 30616 R-DRE-70997 https://reactome.org/PathwayBrowser/#/R-DRE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Danio rerio 30616 R-DRE-71031 https://reactome.org/PathwayBrowser/#/R-DRE-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Danio rerio 30616 R-DRE-71401 https://reactome.org/PathwayBrowser/#/R-DRE-71401 OGDH dimer decarboxylates 2-OG IEA Danio rerio 30616 R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 30616 R-DRE-71802 https://reactome.org/PathwayBrowser/#/R-DRE-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Danio rerio 30616 R-DRE-71850 https://reactome.org/PathwayBrowser/#/R-DRE-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Danio rerio 30616 R-DRE-72621 https://reactome.org/PathwayBrowser/#/R-DRE-72621 Ribosomal scanning IEA Danio rerio 30616 R-DRE-73548 https://reactome.org/PathwayBrowser/#/R-DRE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Danio rerio 30616 R-DRE-73580 https://reactome.org/PathwayBrowser/#/R-DRE-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Danio rerio 30616 R-DRE-73598 https://reactome.org/PathwayBrowser/#/R-DRE-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Danio rerio 30616 R-DRE-73599 https://reactome.org/PathwayBrowser/#/R-DRE-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Danio rerio 30616 R-DRE-73632 https://reactome.org/PathwayBrowser/#/R-DRE-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Danio rerio 30616 R-DRE-73635 https://reactome.org/PathwayBrowser/#/R-DRE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Danio rerio 30616 R-DRE-73647 https://reactome.org/PathwayBrowser/#/R-DRE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Danio rerio 30616 R-DRE-73722 https://reactome.org/PathwayBrowser/#/R-DRE-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Danio rerio 30616 R-DRE-73788 https://reactome.org/PathwayBrowser/#/R-DRE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Danio rerio 30616 R-DRE-73805 https://reactome.org/PathwayBrowser/#/R-DRE-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Danio rerio 30616 R-DRE-73810 https://reactome.org/PathwayBrowser/#/R-DRE-73810 FGAM + ATP => AIR + ADP + Pi IEA Danio rerio 30616 R-DRE-73814 https://reactome.org/PathwayBrowser/#/R-DRE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Danio rerio 30616 R-DRE-74207 https://reactome.org/PathwayBrowser/#/R-DRE-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Danio rerio 30616 R-DRE-74715 https://reactome.org/PathwayBrowser/#/R-DRE-74715 Autophosphorylation of insulin receptor IEA Danio rerio 30616 R-DRE-75125 https://reactome.org/PathwayBrowser/#/R-DRE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Danio rerio 30616 R-DRE-75126 https://reactome.org/PathwayBrowser/#/R-DRE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Danio rerio 30616 R-DRE-75848 https://reactome.org/PathwayBrowser/#/R-DRE-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Danio rerio 30616 R-DRE-77071 https://reactome.org/PathwayBrowser/#/R-DRE-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Danio rerio 30616 R-DRE-844438 https://reactome.org/PathwayBrowser/#/R-DRE-844438 NLRP1 oligomerizes IEA Danio rerio 30616 R-DRE-873918 https://reactome.org/PathwayBrowser/#/R-DRE-873918 Transphosphorylation of JAK1 IEA Danio rerio 30616 R-DRE-873919 https://reactome.org/PathwayBrowser/#/R-DRE-873919 Phosphorylation of JAK2 IEA Danio rerio 30616 R-DRE-873922 https://reactome.org/PathwayBrowser/#/R-DRE-873922 Phosphorylation of STAT1 by JAK kinases IEA Danio rerio 30616 R-DRE-873924 https://reactome.org/PathwayBrowser/#/R-DRE-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Danio rerio 30616 R-DRE-877187 https://reactome.org/PathwayBrowser/#/R-DRE-877187 P2X7 mediates loss of intracellular K+ IEA Danio rerio 30616 R-DRE-877198 https://reactome.org/PathwayBrowser/#/R-DRE-877198 P2X7 mediates membrane pores that include pannexin-1 IEA Danio rerio 30616 R-DRE-879222 https://reactome.org/PathwayBrowser/#/R-DRE-879222 MDP:NLRP1 binds ATP IEA Danio rerio 30616 R-DRE-8848005 https://reactome.org/PathwayBrowser/#/R-DRE-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Danio rerio 30616 R-DRE-8848077 https://reactome.org/PathwayBrowser/#/R-DRE-8848077 PTK6 phosphorylates STAP2 IEA Danio rerio 30616 R-DRE-8848436 https://reactome.org/PathwayBrowser/#/R-DRE-8848436 PTK6 phosphorylates CDKN1B IEA Danio rerio 30616 R-DRE-8848606 https://reactome.org/PathwayBrowser/#/R-DRE-8848606 PTK6 phosphorylates PXN IEA Danio rerio 30616 R-DRE-8848758 https://reactome.org/PathwayBrowser/#/R-DRE-8848758 PTK6 phosphorylates AKT1 IEA Danio rerio 30616 R-DRE-8848776 https://reactome.org/PathwayBrowser/#/R-DRE-8848776 PTK6 phosphorylates DOK1 IEA Danio rerio 30616 R-DRE-8848818 https://reactome.org/PathwayBrowser/#/R-DRE-8848818 PTK6 phosphorylates CBL IEA Danio rerio 30616 R-DRE-8848975 https://reactome.org/PathwayBrowser/#/R-DRE-8848975 PTK6 phosphorylates KHDRBS1 IEA Danio rerio 30616 R-DRE-8849032 https://reactome.org/PathwayBrowser/#/R-DRE-8849032 PTK6 phosphorylates KHDRBS2 IEA Danio rerio 30616 R-DRE-8849068 https://reactome.org/PathwayBrowser/#/R-DRE-8849068 PTK6 phosphorylates ARHGAP35 IEA Danio rerio 30616 R-DRE-8849463 https://reactome.org/PathwayBrowser/#/R-DRE-8849463 PTK6 phosphorylates SFPQ IEA Danio rerio 30616 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 30616 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 30616 R-DRE-8852128 https://reactome.org/PathwayBrowser/#/R-DRE-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Danio rerio 30616 R-DRE-8852131 https://reactome.org/PathwayBrowser/#/R-DRE-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Danio rerio 30616 R-DRE-8852132 https://reactome.org/PathwayBrowser/#/R-DRE-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Danio rerio 30616 R-DRE-8852134 https://reactome.org/PathwayBrowser/#/R-DRE-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Danio rerio 30616 R-DRE-8852317 https://reactome.org/PathwayBrowser/#/R-DRE-8852317 PLK1 phosphorylates GTSE1 IEA Danio rerio 30616 R-DRE-8852552 https://reactome.org/PathwayBrowser/#/R-DRE-8852552 MST1R autophosphorylates IEA Danio rerio 30616 R-DRE-8853444 https://reactome.org/PathwayBrowser/#/R-DRE-8853444 AURKA phosphorylates PHLDA1 IEA Danio rerio 30616 R-DRE-8866405 https://reactome.org/PathwayBrowser/#/R-DRE-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 30616 R-DRE-8869607 https://reactome.org/PathwayBrowser/#/R-DRE-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Danio rerio 30616 R-DRE-8869627 https://reactome.org/PathwayBrowser/#/R-DRE-8869627 NMRK2 phosphorylates NR to yield NMN IEA Danio rerio 30616 R-DRE-8875451 https://reactome.org/PathwayBrowser/#/R-DRE-8875451 MET phosphorylates CBL IEA Danio rerio 30616 R-DRE-8931653 https://reactome.org/PathwayBrowser/#/R-DRE-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Danio rerio 30616 R-DRE-8937807 https://reactome.org/PathwayBrowser/#/R-DRE-8937807 SRC phosphorylates RUNX3 IEA Danio rerio 30616 R-DRE-8939204 https://reactome.org/PathwayBrowser/#/R-DRE-8939204 ESTG binds ESR1:chaperone complex IEA Danio rerio 30616 R-DRE-8939959 https://reactome.org/PathwayBrowser/#/R-DRE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Danio rerio 30616 R-DRE-8942575 https://reactome.org/PathwayBrowser/#/R-DRE-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Danio rerio 30616 R-DRE-8942607 https://reactome.org/PathwayBrowser/#/R-DRE-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Danio rerio 30616 R-DRE-8944454 https://reactome.org/PathwayBrowser/#/R-DRE-8944454 mTORC1 phosphorylates MAF1 IEA Danio rerio 30616 R-DRE-8948143 https://reactome.org/PathwayBrowser/#/R-DRE-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Danio rerio 30616 R-DRE-8948757 https://reactome.org/PathwayBrowser/#/R-DRE-8948757 AKT phosphorylates MKRN1 IEA Danio rerio 30616 R-DRE-8951648 https://reactome.org/PathwayBrowser/#/R-DRE-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Danio rerio 30616 R-DRE-8951656 https://reactome.org/PathwayBrowser/#/R-DRE-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Danio rerio 30616 R-DRE-8955844 https://reactome.org/PathwayBrowser/#/R-DRE-8955844 RBKS phosphorylates ribose to R5P IEA Danio rerio 30616 R-DRE-8959510 https://reactome.org/PathwayBrowser/#/R-DRE-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Danio rerio 30616 R-DRE-8964242 https://reactome.org/PathwayBrowser/#/R-DRE-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Danio rerio 30616 R-DRE-8986994 https://reactome.org/PathwayBrowser/#/R-DRE-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Danio rerio 30616 R-DRE-8987012 https://reactome.org/PathwayBrowser/#/R-DRE-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Danio rerio 30616 R-DRE-8987084 https://reactome.org/PathwayBrowser/#/R-DRE-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Danio rerio 30616 R-DRE-8987129 https://reactome.org/PathwayBrowser/#/R-DRE-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Danio rerio 30616 R-DRE-8987150 https://reactome.org/PathwayBrowser/#/R-DRE-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Danio rerio 30616 R-DRE-8987179 https://reactome.org/PathwayBrowser/#/R-DRE-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Danio rerio 30616 R-DRE-8987255 https://reactome.org/PathwayBrowser/#/R-DRE-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Danio rerio 30616 R-DRE-9006850 https://reactome.org/PathwayBrowser/#/R-DRE-9006850 IL21 receptor JAK phosphorylation IEA Danio rerio 30616 R-DRE-9006870 https://reactome.org/PathwayBrowser/#/R-DRE-9006870 IL21 receptor STAT phosphorylation IEA Danio rerio 30616 R-DRE-9008043 https://reactome.org/PathwayBrowser/#/R-DRE-9008043 MAPK8 phosphorylation IEA Danio rerio 30616 R-DRE-9008684 https://reactome.org/PathwayBrowser/#/R-DRE-9008684 TBK1 phosphorylation IEA Danio rerio 30616 R-DRE-9012268 https://reactome.org/PathwayBrowser/#/R-DRE-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Danio rerio 30616 R-DRE-9021609 https://reactome.org/PathwayBrowser/#/R-DRE-9021609 ESR-associated SRC autophosphorylates IEA Danio rerio 30616 R-DRE-909552 https://reactome.org/PathwayBrowser/#/R-DRE-909552 Phosphorylation of STAT1 at Ser727 IEA Danio rerio 30616 R-DRE-913996 https://reactome.org/PathwayBrowser/#/R-DRE-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Danio rerio 30616 R-DRE-917841 https://reactome.org/PathwayBrowser/#/R-DRE-917841 Acidification of Tf:TfR1 containing endosome IEA Danio rerio 30616 R-DRE-927889 https://reactome.org/PathwayBrowser/#/R-DRE-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Danio rerio 30616 R-DRE-936802 https://reactome.org/PathwayBrowser/#/R-DRE-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Danio rerio 30616 R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 30616 R-DRE-939763 https://reactome.org/PathwayBrowser/#/R-DRE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Danio rerio 30616 R-DRE-947591 https://reactome.org/PathwayBrowser/#/R-DRE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Danio rerio 30616 R-DRE-9606884 https://reactome.org/PathwayBrowser/#/R-DRE-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Danio rerio 30616 R-DRE-9610153 https://reactome.org/PathwayBrowser/#/R-DRE-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Danio rerio 30616 R-DRE-9610156 https://reactome.org/PathwayBrowser/#/R-DRE-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Danio rerio 30616 R-DRE-9612501 https://reactome.org/PathwayBrowser/#/R-DRE-9612501 SGK phosphorylates CREB1 IEA Danio rerio 30616 R-DRE-9624526 https://reactome.org/PathwayBrowser/#/R-DRE-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Danio rerio 30616 R-DRE-9624800 https://reactome.org/PathwayBrowser/#/R-DRE-9624800 CDK1 phosphorylates LBR IEA Danio rerio 30616 R-DRE-9626817 https://reactome.org/PathwayBrowser/#/R-DRE-9626817 PKC phosphorylates NCF1 IEA Danio rerio 30616 R-DRE-9627056 https://reactome.org/PathwayBrowser/#/R-DRE-9627056 Procaspase 9 forms dimer IEA Danio rerio 30616 R-DRE-9627089 https://reactome.org/PathwayBrowser/#/R-DRE-9627089 CASP9 is phosphorylated at T412 IEA Danio rerio 30616 R-DRE-9632868 https://reactome.org/PathwayBrowser/#/R-DRE-9632868 CDKN1B is phosphorylated in response to estrogen IEA Danio rerio 30616 R-DRE-964958 https://reactome.org/PathwayBrowser/#/R-DRE-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Danio rerio 30616 R-DRE-964962 https://reactome.org/PathwayBrowser/#/R-DRE-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Danio rerio 30616 R-DRE-964970 https://reactome.org/PathwayBrowser/#/R-DRE-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Danio rerio 30616 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 30616 R-DRE-9684118 https://reactome.org/PathwayBrowser/#/R-DRE-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Danio rerio 30616 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 30616 R-DRE-9699579 https://reactome.org/PathwayBrowser/#/R-DRE-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Danio rerio 30616 R-DRE-9700171 https://reactome.org/PathwayBrowser/#/R-DRE-9700171 Active ALK phosphorylates PLCG1 IEA Danio rerio 30616 R-DRE-9705925 https://reactome.org/PathwayBrowser/#/R-DRE-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Danio rerio 30616 R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 30616 R-DRE-9706837 https://reactome.org/PathwayBrowser/#/R-DRE-9706837 AR binds AR antagonists IEA Danio rerio 30616 R-DRE-9709547 https://reactome.org/PathwayBrowser/#/R-DRE-9709547 ESTG binds ESR2:chaperone complex IEA Danio rerio 30616 R-DRE-9716913 https://reactome.org/PathwayBrowser/#/R-DRE-9716913 ESR1 binds ESR1 antagonists IEA Danio rerio 30616 R-DRE-9716947 https://reactome.org/PathwayBrowser/#/R-DRE-9716947 ESR1 binds ESR1 agonists IEA Danio rerio 30616 R-DRE-9725855 https://reactome.org/PathwayBrowser/#/R-DRE-9725855 NR3C2 binds NR3C2 antagonists IEA Danio rerio 30616 R-DRE-9725885 https://reactome.org/PathwayBrowser/#/R-DRE-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Danio rerio 30616 R-DRE-9726509 https://reactome.org/PathwayBrowser/#/R-DRE-9726509 NR3C2 binds fludrocortisone IEA Danio rerio 30616 R-DRE-9726580 https://reactome.org/PathwayBrowser/#/R-DRE-9726580 PGR binds PGR agonists IEA Danio rerio 30616 R-DRE-9726621 https://reactome.org/PathwayBrowser/#/R-DRE-9726621 PGR binds PGR antagonists IEA Danio rerio 30616 R-DRE-9731111 https://reactome.org/PathwayBrowser/#/R-DRE-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Danio rerio 30616 R-DRE-9734547 https://reactome.org/PathwayBrowser/#/R-DRE-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Danio rerio 30616 R-DRE-9748949 https://reactome.org/PathwayBrowser/#/R-DRE-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Danio rerio 30616 R-DRE-9748963 https://reactome.org/PathwayBrowser/#/R-DRE-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Danio rerio 30616 R-DRE-9748969 https://reactome.org/PathwayBrowser/#/R-DRE-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Danio rerio 30616 R-DRE-9748999 https://reactome.org/PathwayBrowser/#/R-DRE-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Danio rerio 30616 R-DRE-9749971 https://reactome.org/PathwayBrowser/#/R-DRE-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Danio rerio 30616 R-DRE-9750546 https://reactome.org/PathwayBrowser/#/R-DRE-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 30616 R-DRE-9750617 https://reactome.org/PathwayBrowser/#/R-DRE-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 30616 R-DRE-9750656 https://reactome.org/PathwayBrowser/#/R-DRE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Danio rerio 30616 R-DRE-9753278 https://reactome.org/PathwayBrowser/#/R-DRE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 30616 R-DRE-9753283 https://reactome.org/PathwayBrowser/#/R-DRE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 30616 R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 30616 R-DRE-9754974 https://reactome.org/PathwayBrowser/#/R-DRE-9754974 ADK phosphorylates RBV IEA Danio rerio 30616 R-DRE-9755013 https://reactome.org/PathwayBrowser/#/R-DRE-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Danio rerio 30616 R-DRE-9796053 https://reactome.org/PathwayBrowser/#/R-DRE-9796053 PRKCI phosphorylates NFE2L2 IEA Danio rerio 30616 R-DRE-9824977 https://reactome.org/PathwayBrowser/#/R-DRE-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Danio rerio 30616 R-DRE-982807 https://reactome.org/PathwayBrowser/#/R-DRE-982807 JAK2 phosphorylation of GHR IEA Danio rerio 30616 R-DRE-982810 https://reactome.org/PathwayBrowser/#/R-DRE-982810 JAK2 phosphorylation IEA Danio rerio 30616 R-DRE-983140 https://reactome.org/PathwayBrowser/#/R-DRE-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Danio rerio 30616 R-DRE-983153 https://reactome.org/PathwayBrowser/#/R-DRE-983153 E1 mediated ubiquitin activation IEA Danio rerio 30616 R-DRE-983156 https://reactome.org/PathwayBrowser/#/R-DRE-983156 Polyubiquitination of substrate IEA Danio rerio 30616 R-DRE-9836184 https://reactome.org/PathwayBrowser/#/R-DRE-9836184 p-PKR dimer phosphorylates CDK1 IEA Danio rerio 30616 R-DRE-9836322 https://reactome.org/PathwayBrowser/#/R-DRE-9836322 p-PKR dimer phosphorylates MKK6 IEA Danio rerio 30616 R-DRE-9836362 https://reactome.org/PathwayBrowser/#/R-DRE-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Danio rerio 30616 R-DRE-9836383 https://reactome.org/PathwayBrowser/#/R-DRE-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Danio rerio 30616 R-DRE-9836515 https://reactome.org/PathwayBrowser/#/R-DRE-9836515 p-PKR dimer phosphorylates PTPN2 IEA Danio rerio 30616 R-DRE-9837337 https://reactome.org/PathwayBrowser/#/R-DRE-9837337 DCAKD phosphorylates DP-CoA IEA Danio rerio 30616 R-DRE-9838321 https://reactome.org/PathwayBrowser/#/R-DRE-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Danio rerio 30616 R-DRE-9839105 https://reactome.org/PathwayBrowser/#/R-DRE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Danio rerio 30616 R-DRE-9839113 https://reactome.org/PathwayBrowser/#/R-DRE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Danio rerio 30616 R-DRE-9842648 https://reactome.org/PathwayBrowser/#/R-DRE-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 IEA Danio rerio 30616 R-DRE-9851972 https://reactome.org/PathwayBrowser/#/R-DRE-9851972 PLK1 phosphorylates FIRRM at S43 IEA Danio rerio 30616 R-DRE-9853369 https://reactome.org/PathwayBrowser/#/R-DRE-9853369 PLK1 phosphorylates FIRMM at S744 IEA Danio rerio 30616 R-DRE-994137 https://reactome.org/PathwayBrowser/#/R-DRE-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Danio rerio 30616 R-DRE-994140 https://reactome.org/PathwayBrowser/#/R-DRE-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Danio rerio 30616 R-GGA-109624 https://reactome.org/PathwayBrowser/#/R-GGA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Gallus gallus 30616 R-GGA-109671 https://reactome.org/PathwayBrowser/#/R-GGA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Gallus gallus 30616 R-GGA-109699 https://reactome.org/PathwayBrowser/#/R-GGA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-109759 https://reactome.org/PathwayBrowser/#/R-GGA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Gallus gallus 30616 R-GGA-109903 https://reactome.org/PathwayBrowser/#/R-GGA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Gallus gallus 30616 R-GGA-110133 https://reactome.org/PathwayBrowser/#/R-GGA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Gallus gallus 30616 R-GGA-110137 https://reactome.org/PathwayBrowser/#/R-GGA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Gallus gallus 30616 R-GGA-110138 https://reactome.org/PathwayBrowser/#/R-GGA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 30616 R-GGA-110141 https://reactome.org/PathwayBrowser/#/R-GGA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Gallus gallus 30616 R-GGA-110144 https://reactome.org/PathwayBrowser/#/R-GGA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Gallus gallus 30616 R-GGA-110145 https://reactome.org/PathwayBrowser/#/R-GGA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Gallus gallus 30616 R-GGA-1112510 https://reactome.org/PathwayBrowser/#/R-GGA-1112510 IL6ST is tyrosine phosphorylated IEA Gallus gallus 30616 R-GGA-1112514 https://reactome.org/PathwayBrowser/#/R-GGA-1112514 JAK activation IEA Gallus gallus 30616 R-GGA-1112602 https://reactome.org/PathwayBrowser/#/R-GGA-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Gallus gallus 30616 R-GGA-1112703 https://reactome.org/PathwayBrowser/#/R-GGA-1112703 PTPN11 is phosphorylated IEA Gallus gallus 30616 R-GGA-1112727 https://reactome.org/PathwayBrowser/#/R-GGA-1112727 Serine phosphorylation of STATs IEA Gallus gallus 30616 R-GGA-111898 https://reactome.org/PathwayBrowser/#/R-GGA-111898 Phosphorylation of cPLA2 by ERK-2 IEA Gallus gallus 30616 R-GGA-111915 https://reactome.org/PathwayBrowser/#/R-GGA-111915 CAMK4 autophosphorylates IEA Gallus gallus 30616 R-GGA-111930 https://reactome.org/PathwayBrowser/#/R-GGA-111930 Adenylate cyclase produces cAMP IEA Gallus gallus 30616 R-GGA-111970 https://reactome.org/PathwayBrowser/#/R-GGA-111970 PKC phosphorylates GRK2 IEA Gallus gallus 30616 R-GGA-112342 https://reactome.org/PathwayBrowser/#/R-GGA-112342 Inactivation of MAP2K1 by CDK1 IEA Gallus gallus 30616 R-GGA-112381 https://reactome.org/PathwayBrowser/#/R-GGA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Gallus gallus 30616 R-GGA-114252 https://reactome.org/PathwayBrowser/#/R-GGA-114252 Cleavage of Procaspase-3 by the apoptosome IEA Gallus gallus 30616 R-GGA-114254 https://reactome.org/PathwayBrowser/#/R-GGA-114254 CYCS binds to APAF1 IEA Gallus gallus 30616 R-GGA-114256 https://reactome.org/PathwayBrowser/#/R-GGA-114256 CYCS:APAF1 binds procaspase-9 IEA Gallus gallus 30616 R-GGA-114261 https://reactome.org/PathwayBrowser/#/R-GGA-114261 Cleavage of Procaspase-7 by the apoptosome IEA Gallus gallus 30616 R-GGA-114683 https://reactome.org/PathwayBrowser/#/R-GGA-114683 Phosphorylation of Platelet Sec-1 IEA Gallus gallus 30616 R-GGA-1168459 https://reactome.org/PathwayBrowser/#/R-GGA-1168459 Lyn activates ERK IEA Gallus gallus 30616 R-GGA-1168635 https://reactome.org/PathwayBrowser/#/R-GGA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Gallus gallus 30616 R-GGA-1181149 https://reactome.org/PathwayBrowser/#/R-GGA-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Gallus gallus 30616 R-GGA-1226094 https://reactome.org/PathwayBrowser/#/R-GGA-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Gallus gallus 30616 R-GGA-1226095 https://reactome.org/PathwayBrowser/#/R-GGA-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Gallus gallus 30616 R-GGA-1227783 https://reactome.org/PathwayBrowser/#/R-GGA-1227783 Phosphorylation of IKKs complex mediated by MEKK1 IEA Gallus gallus 30616 R-GGA-1227881 https://reactome.org/PathwayBrowser/#/R-GGA-1227881 Phosphorylation and release of IRF3 IEA Gallus gallus 30616 R-GGA-1227885 https://reactome.org/PathwayBrowser/#/R-GGA-1227885 TBK1/IKK epsilon bind to TANK:TRAF3/TRAF6 complex followed by their activation IEA Gallus gallus 30616 R-GGA-1250195 https://reactome.org/PathwayBrowser/#/R-GGA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Gallus gallus 30616 R-GGA-1250315 https://reactome.org/PathwayBrowser/#/R-GGA-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Gallus gallus 30616 R-GGA-1250348 https://reactome.org/PathwayBrowser/#/R-GGA-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Gallus gallus 30616 R-GGA-1250370 https://reactome.org/PathwayBrowser/#/R-GGA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Gallus gallus 30616 R-GGA-1250462 https://reactome.org/PathwayBrowser/#/R-GGA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Gallus gallus 30616 R-GGA-1295540 https://reactome.org/PathwayBrowser/#/R-GGA-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Gallus gallus 30616 R-GGA-1296024 https://reactome.org/PathwayBrowser/#/R-GGA-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Gallus gallus 30616 R-GGA-1306957 https://reactome.org/PathwayBrowser/#/R-GGA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus 30616 R-GGA-1306979 https://reactome.org/PathwayBrowser/#/R-GGA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Gallus gallus 30616 R-GGA-1307963 https://reactome.org/PathwayBrowser/#/R-GGA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Gallus gallus 30616 R-GGA-1358791 https://reactome.org/PathwayBrowser/#/R-GGA-1358791 Phosphorylation of USP8 by P-AKT IEA Gallus gallus 30616 R-GGA-1362270 https://reactome.org/PathwayBrowser/#/R-GGA-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Gallus gallus 30616 R-GGA-1369028 https://reactome.org/PathwayBrowser/#/R-GGA-1369028 ABCAs mediate lipid efflux IEA Gallus gallus 30616 R-GGA-1369052 https://reactome.org/PathwayBrowser/#/R-GGA-1369052 ABCAs mediate lipid influx IEA Gallus gallus 30616 R-GGA-1369065 https://reactome.org/PathwayBrowser/#/R-GGA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Gallus gallus 30616 R-GGA-1370505 https://reactome.org/PathwayBrowser/#/R-GGA-1370505 PRLR is phosphorylated at Ser-349 IEA Gallus gallus 30616 R-GGA-139855 https://reactome.org/PathwayBrowser/#/R-GGA-139855 P2X1-mediated entry of Ca++ from plasma IEA Gallus gallus 30616 R-GGA-139908 https://reactome.org/PathwayBrowser/#/R-GGA-139908 Phosphorylation of DLC2 by MAPK8 IEA Gallus gallus 30616 R-GGA-139918 https://reactome.org/PathwayBrowser/#/R-GGA-139918 Phosphorylation of BIM by JNK IEA Gallus gallus 30616 R-GGA-1433418 https://reactome.org/PathwayBrowser/#/R-GGA-1433418 Phosphorylation of JAK2 IEA Gallus gallus 30616 R-GGA-1433454 https://reactome.org/PathwayBrowser/#/R-GGA-1433454 Phosphorylation of GAB2 by SFKs IEA Gallus gallus 30616 R-GGA-1433488 https://reactome.org/PathwayBrowser/#/R-GGA-1433488 Phosphorylation of SHP2 by SFKs IEA Gallus gallus 30616 R-GGA-1433506 https://reactome.org/PathwayBrowser/#/R-GGA-1433506 Phosphorylation of APS IEA Gallus gallus 30616 R-GGA-1433508 https://reactome.org/PathwayBrowser/#/R-GGA-1433508 PKC alpha interacts with and phosphorylates KIT IEA Gallus gallus 30616 R-GGA-1433514 https://reactome.org/PathwayBrowser/#/R-GGA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Gallus gallus 30616 R-GGA-1454916 https://reactome.org/PathwayBrowser/#/R-GGA-1454916 The ABCC family mediates organic anion transport IEA Gallus gallus 30616 R-GGA-1454928 https://reactome.org/PathwayBrowser/#/R-GGA-1454928 ABCG4 may mediate cholesterol efflux IEA Gallus gallus 30616 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 30616 R-GGA-1467466 https://reactome.org/PathwayBrowser/#/R-GGA-1467466 ABCA4 mediates atRAL transport IEA Gallus gallus 30616 R-GGA-1470009 https://reactome.org/PathwayBrowser/#/R-GGA-1470009 Phosphorylation of STATs IEA Gallus gallus 30616 R-GGA-1472121 https://reactome.org/PathwayBrowser/#/R-GGA-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Gallus gallus 30616 R-GGA-1475422 https://reactome.org/PathwayBrowser/#/R-GGA-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Gallus gallus 30616 R-GGA-1483004 https://reactome.org/PathwayBrowser/#/R-GGA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Gallus gallus 30616 R-GGA-1483222 https://reactome.org/PathwayBrowser/#/R-GGA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Gallus gallus 30616 R-GGA-1497853 https://reactome.org/PathwayBrowser/#/R-GGA-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Gallus gallus 30616 R-GGA-1524186 https://reactome.org/PathwayBrowser/#/R-GGA-1524186 Phosphorylation of PLCgamma by PDGFR IEA Gallus gallus 30616 R-GGA-1549526 https://reactome.org/PathwayBrowser/#/R-GGA-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Gallus gallus 30616 R-GGA-156673 https://reactome.org/PathwayBrowser/#/R-GGA-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Gallus gallus 30616 R-GGA-156682 https://reactome.org/PathwayBrowser/#/R-GGA-156682 PLK1 phosphorylates NUDC IEA Gallus gallus 30616 R-GGA-156699 https://reactome.org/PathwayBrowser/#/R-GGA-156699 Inactivation of Wee1 kinase IEA Gallus gallus 30616 R-GGA-159425 https://reactome.org/PathwayBrowser/#/R-GGA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 30616 R-GGA-159443 https://reactome.org/PathwayBrowser/#/R-GGA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 30616 R-GGA-159567 https://reactome.org/PathwayBrowser/#/R-GGA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Gallus gallus 30616 R-GGA-163010 https://reactome.org/PathwayBrowser/#/R-GGA-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Gallus gallus 30616 R-GGA-163215 https://reactome.org/PathwayBrowser/#/R-GGA-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Gallus gallus 30616 R-GGA-1632857 https://reactome.org/PathwayBrowser/#/R-GGA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Gallus gallus 30616 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus 30616 R-GGA-1638845 https://reactome.org/PathwayBrowser/#/R-GGA-1638845 CERK phosphorylates CERA to form C1P IEA Gallus gallus 30616 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus 30616 R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus 30616 R-GGA-165692 https://reactome.org/PathwayBrowser/#/R-GGA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Gallus gallus 30616 R-GGA-165718 https://reactome.org/PathwayBrowser/#/R-GGA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Gallus gallus 30616 R-GGA-165726 https://reactome.org/PathwayBrowser/#/R-GGA-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Gallus gallus 30616 R-GGA-165758 https://reactome.org/PathwayBrowser/#/R-GGA-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Gallus gallus 30616 R-GGA-165766 https://reactome.org/PathwayBrowser/#/R-GGA-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Gallus gallus 30616 R-GGA-165777 https://reactome.org/PathwayBrowser/#/R-GGA-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Gallus gallus 30616 R-GGA-166245 https://reactome.org/PathwayBrowser/#/R-GGA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Gallus gallus 30616 R-GGA-1675773 https://reactome.org/PathwayBrowser/#/R-GGA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Gallus gallus 30616 R-GGA-1675776 https://reactome.org/PathwayBrowser/#/R-GGA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Gallus gallus 30616 R-GGA-1675780 https://reactome.org/PathwayBrowser/#/R-GGA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Gallus gallus 30616 R-GGA-1675810 https://reactome.org/PathwayBrowser/#/R-GGA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Gallus gallus 30616 R-GGA-1675813 https://reactome.org/PathwayBrowser/#/R-GGA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Gallus gallus 30616 R-GGA-1675883 https://reactome.org/PathwayBrowser/#/R-GGA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Gallus gallus 30616 R-GGA-1675928 https://reactome.org/PathwayBrowser/#/R-GGA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Gallus gallus 30616 R-GGA-1675939 https://reactome.org/PathwayBrowser/#/R-GGA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Gallus gallus 30616 R-GGA-1675961 https://reactome.org/PathwayBrowser/#/R-GGA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Gallus gallus 30616 R-GGA-1675974 https://reactome.org/PathwayBrowser/#/R-GGA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Gallus gallus 30616 R-GGA-1676024 https://reactome.org/PathwayBrowser/#/R-GGA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Gallus gallus 30616 R-GGA-1676048 https://reactome.org/PathwayBrowser/#/R-GGA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Gallus gallus 30616 R-GGA-1676082 https://reactome.org/PathwayBrowser/#/R-GGA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Gallus gallus 30616 R-GGA-1676109 https://reactome.org/PathwayBrowser/#/R-GGA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Gallus gallus 30616 R-GGA-1676134 https://reactome.org/PathwayBrowser/#/R-GGA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Gallus gallus 30616 R-GGA-1676145 https://reactome.org/PathwayBrowser/#/R-GGA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Gallus gallus 30616 R-GGA-1676185 https://reactome.org/PathwayBrowser/#/R-GGA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Gallus gallus 30616 R-GGA-1676206 https://reactome.org/PathwayBrowser/#/R-GGA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Gallus gallus 30616 R-GGA-1678923 https://reactome.org/PathwayBrowser/#/R-GGA-1678923 TLR folding by chaperones GP96 and CNPY3 IEA Gallus gallus 30616 R-GGA-1678944 https://reactome.org/PathwayBrowser/#/R-GGA-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Gallus gallus 30616 R-GGA-168053 https://reactome.org/PathwayBrowser/#/R-GGA-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Gallus gallus 30616 R-GGA-168136 https://reactome.org/PathwayBrowser/#/R-GGA-168136 Activated JNKs phosphorylate c-JUN IEA Gallus gallus 30616 R-GGA-168162 https://reactome.org/PathwayBrowser/#/R-GGA-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Gallus gallus 30616 R-GGA-169905 https://reactome.org/PathwayBrowser/#/R-GGA-169905 ARMS is phosphorylated by active TrkA receptor IEA Gallus gallus 30616 R-GGA-170026 https://reactome.org/PathwayBrowser/#/R-GGA-170026 Protons are translocated from the intermembrane space to the matrix IEA Gallus gallus 30616 R-GGA-170087 https://reactome.org/PathwayBrowser/#/R-GGA-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Gallus gallus 30616 R-GGA-170676 https://reactome.org/PathwayBrowser/#/R-GGA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Gallus gallus 30616 R-GGA-170843 https://reactome.org/PathwayBrowser/#/R-GGA-170843 TGFBR2 phosphorylates TGFBR1 IEA Gallus gallus 30616 R-GGA-170868 https://reactome.org/PathwayBrowser/#/R-GGA-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Gallus gallus 30616 R-GGA-170977 https://reactome.org/PathwayBrowser/#/R-GGA-170977 FRS2 is phosphorylated by active TrkA receptor IEA Gallus gallus 30616 R-GGA-174079 https://reactome.org/PathwayBrowser/#/R-GGA-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Gallus gallus 30616 R-GGA-174164 https://reactome.org/PathwayBrowser/#/R-GGA-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Gallus gallus 30616 R-GGA-174174 https://reactome.org/PathwayBrowser/#/R-GGA-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Gallus gallus 30616 R-GGA-174389 https://reactome.org/PathwayBrowser/#/R-GGA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Gallus gallus 30616 R-GGA-174391 https://reactome.org/PathwayBrowser/#/R-GGA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Gallus gallus 30616 R-GGA-174392 https://reactome.org/PathwayBrowser/#/R-GGA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Gallus gallus 30616 R-GGA-174394 https://reactome.org/PathwayBrowser/#/R-GGA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Gallus gallus 30616 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus 30616 R-GGA-176298 https://reactome.org/PathwayBrowser/#/R-GGA-176298 Activation of claspin IEA Gallus gallus 30616 R-GGA-177157 https://reactome.org/PathwayBrowser/#/R-GGA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Gallus gallus 30616 R-GGA-177275 https://reactome.org/PathwayBrowser/#/R-GGA-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Gallus gallus 30616 R-GGA-177284 https://reactome.org/PathwayBrowser/#/R-GGA-177284 PKA phosphorylates PDE4B IEA Gallus gallus 30616 R-GGA-177930 https://reactome.org/PathwayBrowser/#/R-GGA-177930 GAB1 phosphorylation by EGFR kinase IEA Gallus gallus 30616 R-GGA-177933 https://reactome.org/PathwayBrowser/#/R-GGA-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Gallus gallus 30616 R-GGA-177934 https://reactome.org/PathwayBrowser/#/R-GGA-177934 EGFR autophosphorylation IEA Gallus gallus 30616 R-GGA-177937 https://reactome.org/PathwayBrowser/#/R-GGA-177937 Phosphorylation of EGFR by SRC kinase IEA Gallus gallus 30616 R-GGA-177939 https://reactome.org/PathwayBrowser/#/R-GGA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Gallus gallus 30616 R-GGA-182969 https://reactome.org/PathwayBrowser/#/R-GGA-182969 Phosphorylation of CBL (EGFR:CBL) IEA Gallus gallus 30616 R-GGA-183058 https://reactome.org/PathwayBrowser/#/R-GGA-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Gallus gallus 30616 R-GGA-1855153 https://reactome.org/PathwayBrowser/#/R-GGA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Gallus gallus 30616 R-GGA-1855157 https://reactome.org/PathwayBrowser/#/R-GGA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Gallus gallus 30616 R-GGA-1855158 https://reactome.org/PathwayBrowser/#/R-GGA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Gallus gallus 30616 R-GGA-1855162 https://reactome.org/PathwayBrowser/#/R-GGA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Gallus gallus 30616 R-GGA-1855169 https://reactome.org/PathwayBrowser/#/R-GGA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 30616 R-GGA-1855172 https://reactome.org/PathwayBrowser/#/R-GGA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Gallus gallus 30616 R-GGA-1855176 https://reactome.org/PathwayBrowser/#/R-GGA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Gallus gallus 30616 R-GGA-1855179 https://reactome.org/PathwayBrowser/#/R-GGA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Gallus gallus 30616 R-GGA-1855181 https://reactome.org/PathwayBrowser/#/R-GGA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Gallus gallus 30616 R-GGA-1855182 https://reactome.org/PathwayBrowser/#/R-GGA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Gallus gallus 30616 R-GGA-1855185 https://reactome.org/PathwayBrowser/#/R-GGA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 30616 R-GGA-1855193 https://reactome.org/PathwayBrowser/#/R-GGA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Gallus gallus 30616 R-GGA-1855194 https://reactome.org/PathwayBrowser/#/R-GGA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Gallus gallus 30616 R-GGA-1855197 https://reactome.org/PathwayBrowser/#/R-GGA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 30616 R-GGA-1855206 https://reactome.org/PathwayBrowser/#/R-GGA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 30616 R-GGA-1855207 https://reactome.org/PathwayBrowser/#/R-GGA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Gallus gallus 30616 R-GGA-1855216 https://reactome.org/PathwayBrowser/#/R-GGA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Gallus gallus 30616 R-GGA-1855223 https://reactome.org/PathwayBrowser/#/R-GGA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Gallus gallus 30616 R-GGA-1855224 https://reactome.org/PathwayBrowser/#/R-GGA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Gallus gallus 30616 R-GGA-1855227 https://reactome.org/PathwayBrowser/#/R-GGA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Gallus gallus 30616 R-GGA-1855228 https://reactome.org/PathwayBrowser/#/R-GGA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 30616 R-GGA-1855230 https://reactome.org/PathwayBrowser/#/R-GGA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Gallus gallus 30616 R-GGA-1855233 https://reactome.org/PathwayBrowser/#/R-GGA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Gallus gallus 30616 R-GGA-186786 https://reactome.org/PathwayBrowser/#/R-GGA-186786 Autophosphorylation of PDGF beta receptors IEA Gallus gallus 30616 R-GGA-186800 https://reactome.org/PathwayBrowser/#/R-GGA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-187520 https://reactome.org/PathwayBrowser/#/R-GGA-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Gallus gallus 30616 R-GGA-187586 https://reactome.org/PathwayBrowser/#/R-GGA-187586 ATP + aspartate + citrulline <=> argininosuccinate + AMP + pyrophosphate TAS Gallus gallus 30616 R-GGA-187688 https://reactome.org/PathwayBrowser/#/R-GGA-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Gallus gallus 30616 R-GGA-187916 https://reactome.org/PathwayBrowser/#/R-GGA-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Gallus gallus 30616 R-GGA-187948 https://reactome.org/PathwayBrowser/#/R-GGA-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Gallus gallus 30616 R-GGA-187949 https://reactome.org/PathwayBrowser/#/R-GGA-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Gallus gallus 30616 R-GGA-187959 https://reactome.org/PathwayBrowser/#/R-GGA-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Gallus gallus 30616 R-GGA-188350 https://reactome.org/PathwayBrowser/#/R-GGA-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Gallus gallus 30616 R-GGA-188390 https://reactome.org/PathwayBrowser/#/R-GGA-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Gallus gallus 30616 R-GGA-190326 https://reactome.org/PathwayBrowser/#/R-GGA-190326 Autocatalytic phosphorylation of FGFR4 IEA Gallus gallus 30616 R-GGA-190385 https://reactome.org/PathwayBrowser/#/R-GGA-190385 Autocatalytic phosphorylation of FGFR3b IEA Gallus gallus 30616 R-GGA-190388 https://reactome.org/PathwayBrowser/#/R-GGA-190388 Autocatalytic phosphorylation of FGFR3c IEA Gallus gallus 30616 R-GGA-190408 https://reactome.org/PathwayBrowser/#/R-GGA-190408 Autocatalytic phosphorylation of FGFR2b IEA Gallus gallus 30616 R-GGA-190413 https://reactome.org/PathwayBrowser/#/R-GGA-190413 Autocatalytic phosphorylation of FGFR2c IEA Gallus gallus 30616 R-GGA-190427 https://reactome.org/PathwayBrowser/#/R-GGA-190427 Autocatalytic phosphorylation of FGFR1b IEA Gallus gallus 30616 R-GGA-190429 https://reactome.org/PathwayBrowser/#/R-GGA-190429 Autocatalytic phosphorylation of FGFR1c IEA Gallus gallus 30616 R-GGA-191062 https://reactome.org/PathwayBrowser/#/R-GGA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Gallus gallus 30616 R-GGA-191380 https://reactome.org/PathwayBrowser/#/R-GGA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Gallus gallus 30616 R-GGA-191414 https://reactome.org/PathwayBrowser/#/R-GGA-191414 MVD decarboxylates MVA5PP to IPPP IEA Gallus gallus 30616 R-GGA-191422 https://reactome.org/PathwayBrowser/#/R-GGA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Gallus gallus 30616 R-GGA-191636 https://reactome.org/PathwayBrowser/#/R-GGA-191636 Phosphorylation of Cx43 by c-src IEA Gallus gallus 30616 R-GGA-192137 https://reactome.org/PathwayBrowser/#/R-GGA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 30616 R-GGA-193362 https://reactome.org/PathwayBrowser/#/R-GGA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Gallus gallus 30616 R-GGA-193401 https://reactome.org/PathwayBrowser/#/R-GGA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 30616 R-GGA-193407 https://reactome.org/PathwayBrowser/#/R-GGA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 30616 R-GGA-193424 https://reactome.org/PathwayBrowser/#/R-GGA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 30616 R-GGA-193703 https://reactome.org/PathwayBrowser/#/R-GGA-193703 IKKbeta is activated IEA Gallus gallus 30616 R-GGA-193705 https://reactome.org/PathwayBrowser/#/R-GGA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Gallus gallus 30616 R-GGA-193711 https://reactome.org/PathwayBrowser/#/R-GGA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 30616 R-GGA-193727 https://reactome.org/PathwayBrowser/#/R-GGA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 30616 R-GGA-193743 https://reactome.org/PathwayBrowser/#/R-GGA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 30616 R-GGA-193766 https://reactome.org/PathwayBrowser/#/R-GGA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 30616 R-GGA-194153 https://reactome.org/PathwayBrowser/#/R-GGA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Gallus gallus 30616 R-GGA-195275 https://reactome.org/PathwayBrowser/#/R-GGA-195275 Phosphorylation of APC component of the destruction complex IEA Gallus gallus 30616 R-GGA-195283 https://reactome.org/PathwayBrowser/#/R-GGA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Gallus gallus 30616 R-GGA-195287 https://reactome.org/PathwayBrowser/#/R-GGA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Gallus gallus 30616 R-GGA-195300 https://reactome.org/PathwayBrowser/#/R-GGA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Gallus gallus 30616 R-GGA-195318 https://reactome.org/PathwayBrowser/#/R-GGA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Gallus gallus 30616 R-GGA-1963581 https://reactome.org/PathwayBrowser/#/R-GGA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Gallus gallus 30616 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 30616 R-GGA-1963586 https://reactome.org/PathwayBrowser/#/R-GGA-1963586 SRC family kinases phosphorylate ERBB2 IEA Gallus gallus 30616 R-GGA-196753 https://reactome.org/PathwayBrowser/#/R-GGA-196753 2xPPCS ligates PPanK with Cys IEA Gallus gallus 30616 R-GGA-196754 https://reactome.org/PathwayBrowser/#/R-GGA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Gallus gallus 30616 R-GGA-196761 https://reactome.org/PathwayBrowser/#/R-GGA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Gallus gallus 30616 R-GGA-196773 https://reactome.org/PathwayBrowser/#/R-GGA-196773 COASY phosphorylates DP-CoA IEA Gallus gallus 30616 R-GGA-196857 https://reactome.org/PathwayBrowser/#/R-GGA-196857 PANK2 phosphorylates PanK IEA Gallus gallus 30616 R-GGA-196929 https://reactome.org/PathwayBrowser/#/R-GGA-196929 FLAD1 phosphorylates FMN IEA Gallus gallus 30616 R-GGA-196964 https://reactome.org/PathwayBrowser/#/R-GGA-196964 RFK:Mg2+ phosphorylates RIB IEA Gallus gallus 30616 R-GGA-197198 https://reactome.org/PathwayBrowser/#/R-GGA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Gallus gallus 30616 R-GGA-197235 https://reactome.org/PathwayBrowser/#/R-GGA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 30616 R-GGA-197271 https://reactome.org/PathwayBrowser/#/R-GGA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Gallus gallus 30616 R-GGA-197958 https://reactome.org/PathwayBrowser/#/R-GGA-197958 FPGS-2 transforms THF to THFPG IEA Gallus gallus 30616 R-GGA-198266 https://reactome.org/PathwayBrowser/#/R-GGA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Gallus gallus 30616 R-GGA-198314 https://reactome.org/PathwayBrowser/#/R-GGA-198314 DAG stimulates protein kinase C-delta IEA Gallus gallus 30616 R-GGA-198599 https://reactome.org/PathwayBrowser/#/R-GGA-198599 AKT phosphorylates MDM2 IEA Gallus gallus 30616 R-GGA-198609 https://reactome.org/PathwayBrowser/#/R-GGA-198609 AKT phosphorylates TSC2, inhibiting it IEA Gallus gallus 30616 R-GGA-198611 https://reactome.org/PathwayBrowser/#/R-GGA-198611 AKT phosphorylates IKKalpha IEA Gallus gallus 30616 R-GGA-198613 https://reactome.org/PathwayBrowser/#/R-GGA-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Gallus gallus 30616 R-GGA-198621 https://reactome.org/PathwayBrowser/#/R-GGA-198621 AKT phosphorylates caspase-9 IEA Gallus gallus 30616 R-GGA-198640 https://reactome.org/PathwayBrowser/#/R-GGA-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Gallus gallus 30616 R-GGA-198669 https://reactome.org/PathwayBrowser/#/R-GGA-198669 p38MAPK phosphorylates MSK1 IEA Gallus gallus 30616 R-GGA-198746 https://reactome.org/PathwayBrowser/#/R-GGA-198746 ERK1/2/5 activate RSK1/2/3 IEA Gallus gallus 30616 R-GGA-198756 https://reactome.org/PathwayBrowser/#/R-GGA-198756 ERK1/2 phosphorylates MSK1 IEA Gallus gallus 30616 R-GGA-199203 https://reactome.org/PathwayBrowser/#/R-GGA-199203 PANK1/3 phosphorylate PanK IEA Gallus gallus 30616 R-GGA-199298 https://reactome.org/PathwayBrowser/#/R-GGA-199298 AKT phosphorylates CREB1 IEA Gallus gallus 30616 R-GGA-199299 https://reactome.org/PathwayBrowser/#/R-GGA-199299 AKT phosphorylates FOXO transcription factors IEA Gallus gallus 30616 R-GGA-199839 https://reactome.org/PathwayBrowser/#/R-GGA-199839 AKT can phosphorylate RSK IEA Gallus gallus 30616 R-GGA-199863 https://reactome.org/PathwayBrowser/#/R-GGA-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Gallus gallus 30616 R-GGA-199895 https://reactome.org/PathwayBrowser/#/R-GGA-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Gallus gallus 30616 R-GGA-199910 https://reactome.org/PathwayBrowser/#/R-GGA-199910 MSK1 activates ATF1 IEA Gallus gallus 30616 R-GGA-199917 https://reactome.org/PathwayBrowser/#/R-GGA-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Gallus gallus 30616 R-GGA-199935 https://reactome.org/PathwayBrowser/#/R-GGA-199935 MSK1 activates CREB IEA Gallus gallus 30616 R-GGA-200318 https://reactome.org/PathwayBrowser/#/R-GGA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Gallus gallus 30616 R-GGA-200326 https://reactome.org/PathwayBrowser/#/R-GGA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Gallus gallus 30616 R-GGA-200421 https://reactome.org/PathwayBrowser/#/R-GGA-200421 Activation of cytosolic AMPK by phosphorylation IEA Gallus gallus 30616 R-GGA-200474 https://reactome.org/PathwayBrowser/#/R-GGA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 30616 R-GGA-200512 https://reactome.org/PathwayBrowser/#/R-GGA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 30616 R-GGA-200555 https://reactome.org/PathwayBrowser/#/R-GGA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Gallus gallus 30616 R-GGA-200681 https://reactome.org/PathwayBrowser/#/R-GGA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Gallus gallus 30616 R-GGA-200682 https://reactome.org/PathwayBrowser/#/R-GGA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Gallus gallus 30616 R-GGA-200711 https://reactome.org/PathwayBrowser/#/R-GGA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Gallus gallus 30616 R-GGA-201035 https://reactome.org/PathwayBrowser/#/R-GGA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Gallus gallus 30616 R-GGA-201443 https://reactome.org/PathwayBrowser/#/R-GGA-201443 Type II receptor phosphorylates type I receptor IEA Gallus gallus 30616 R-GGA-201476 https://reactome.org/PathwayBrowser/#/R-GGA-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Gallus gallus 30616 R-GGA-201510 https://reactome.org/PathwayBrowser/#/R-GGA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Gallus gallus 30616 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 30616 R-GGA-201677 https://reactome.org/PathwayBrowser/#/R-GGA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Gallus gallus 30616 R-GGA-202111 https://reactome.org/PathwayBrowser/#/R-GGA-202111 AKT1 phosphorylates eNOS IEA Gallus gallus 30616 R-GGA-202165 https://reactome.org/PathwayBrowser/#/R-GGA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Gallus gallus 30616 R-GGA-202168 https://reactome.org/PathwayBrowser/#/R-GGA-202168 Phosphorylation of ZAP-70 by Lck IEA Gallus gallus 30616 R-GGA-202174 https://reactome.org/PathwayBrowser/#/R-GGA-202174 Activation of ZAP-70 IEA Gallus gallus 30616 R-GGA-202233 https://reactome.org/PathwayBrowser/#/R-GGA-202233 Inactivation of Lck by Csk IEA Gallus gallus 30616 R-GGA-202248 https://reactome.org/PathwayBrowser/#/R-GGA-202248 Phosphorylation of PLC-gamma1 IEA Gallus gallus 30616 R-GGA-202291 https://reactome.org/PathwayBrowser/#/R-GGA-202291 Activation of Lck IEA Gallus gallus 30616 R-GGA-202365 https://reactome.org/PathwayBrowser/#/R-GGA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-202459 https://reactome.org/PathwayBrowser/#/R-GGA-202459 Phosphorylation of Bcl10 IEA Gallus gallus 30616 R-GGA-202510 https://reactome.org/PathwayBrowser/#/R-GGA-202510 Activation of TAK1-TAB2 complex IEA Gallus gallus 30616 R-GGA-2028284 https://reactome.org/PathwayBrowser/#/R-GGA-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Gallus gallus 30616 R-GGA-2028555 https://reactome.org/PathwayBrowser/#/R-GGA-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Gallus gallus 30616 R-GGA-2028583 https://reactome.org/PathwayBrowser/#/R-GGA-2028583 Phosphorylation of YAP by LATS2 IEA Gallus gallus 30616 R-GGA-2028589 https://reactome.org/PathwayBrowser/#/R-GGA-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Gallus gallus 30616 R-GGA-2028591 https://reactome.org/PathwayBrowser/#/R-GGA-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Gallus gallus 30616 R-GGA-2028598 https://reactome.org/PathwayBrowser/#/R-GGA-2028598 Phosphorylation of YAP by LATS1 IEA Gallus gallus 30616 R-GGA-2028629 https://reactome.org/PathwayBrowser/#/R-GGA-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Gallus gallus 30616 R-GGA-2028635 https://reactome.org/PathwayBrowser/#/R-GGA-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Gallus gallus 30616 R-GGA-2028661 https://reactome.org/PathwayBrowser/#/R-GGA-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Gallus gallus 30616 R-GGA-2028670 https://reactome.org/PathwayBrowser/#/R-GGA-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Gallus gallus 30616 R-GGA-2028673 https://reactome.org/PathwayBrowser/#/R-GGA-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Gallus gallus 30616 R-GGA-2028675 https://reactome.org/PathwayBrowser/#/R-GGA-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Gallus gallus 30616 R-GGA-2028679 https://reactome.org/PathwayBrowser/#/R-GGA-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Gallus gallus 30616 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus 30616 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus 30616 R-GGA-2029454 https://reactome.org/PathwayBrowser/#/R-GGA-2029454 Autophosphorylation of PAK1 IEA Gallus gallus 30616 R-GGA-2029459 https://reactome.org/PathwayBrowser/#/R-GGA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Gallus gallus 30616 R-GGA-2029460 https://reactome.org/PathwayBrowser/#/R-GGA-2029460 PAK1 phosphorylates LIMK1 IEA Gallus gallus 30616 R-GGA-2029466 https://reactome.org/PathwayBrowser/#/R-GGA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Gallus gallus 30616 R-GGA-2029469 https://reactome.org/PathwayBrowser/#/R-GGA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Gallus gallus 30616 R-GGA-2029473 https://reactome.org/PathwayBrowser/#/R-GGA-2029473 Branching and elongation of mother and daughter filaments IEA Gallus gallus 30616 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus 30616 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 30616 R-GGA-2046085 https://reactome.org/PathwayBrowser/#/R-GGA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Gallus gallus 30616 R-GGA-2046098 https://reactome.org/PathwayBrowser/#/R-GGA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Gallus gallus 30616 R-GGA-205136 https://reactome.org/PathwayBrowser/#/R-GGA-205136 GTP-bound RAC contributes to JNK activation IEA Gallus gallus 30616 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 30616 R-GGA-2060328 https://reactome.org/PathwayBrowser/#/R-GGA-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Gallus gallus 30616 R-GGA-209087 https://reactome.org/PathwayBrowser/#/R-GGA-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Gallus gallus 30616 R-GGA-210291 https://reactome.org/PathwayBrowser/#/R-GGA-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Gallus gallus 30616 R-GGA-211164 https://reactome.org/PathwayBrowser/#/R-GGA-211164 AKT phosphorylates FOXO1A IEA Gallus gallus 30616 R-GGA-212710 https://reactome.org/PathwayBrowser/#/R-GGA-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Gallus gallus 30616 R-GGA-2130194 https://reactome.org/PathwayBrowser/#/R-GGA-2130194 ABL phosphorylates WAVEs IEA Gallus gallus 30616 R-GGA-216723 https://reactome.org/PathwayBrowser/#/R-GGA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Gallus gallus 30616 R-GGA-216757 https://reactome.org/PathwayBrowser/#/R-GGA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Gallus gallus 30616 R-GGA-2168079 https://reactome.org/PathwayBrowser/#/R-GGA-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Gallus gallus 30616 R-GGA-216941 https://reactome.org/PathwayBrowser/#/R-GGA-216941 Phosphorylation of Chk1 by ATR TAS Gallus gallus 30616 R-GGA-217013 https://reactome.org/PathwayBrowser/#/R-GGA-217013 Phosphorylation of RAD51 by tyrosine kinase Abelson family protein members TAS Gallus gallus 30616 R-GGA-217136 https://reactome.org/PathwayBrowser/#/R-GGA-217136 Phosphorylation of Chk1 by ATM upon DNA damage TAS Gallus gallus 30616 R-GGA-2197690 https://reactome.org/PathwayBrowser/#/R-GGA-2197690 Detachment of WASP/WAVE IEA Gallus gallus 30616 R-GGA-2197698 https://reactome.org/PathwayBrowser/#/R-GGA-2197698 Src phosphorylate WASP,N-WASP IEA Gallus gallus 30616 R-GGA-2214351 https://reactome.org/PathwayBrowser/#/R-GGA-2214351 PLK1 phosphorylates GORASP1 IEA Gallus gallus 30616 R-GGA-2267372 https://reactome.org/PathwayBrowser/#/R-GGA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Gallus gallus 30616 R-GGA-2294580 https://reactome.org/PathwayBrowser/#/R-GGA-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Gallus gallus 30616 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-2395412 https://reactome.org/PathwayBrowser/#/R-GGA-2395412 Phosphorylation of SYK IEA Gallus gallus 30616 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus 30616 R-GGA-2404193 https://reactome.org/PathwayBrowser/#/R-GGA-2404193 IGF1R phosphorylates SHC1 IEA Gallus gallus 30616 R-GGA-2404199 https://reactome.org/PathwayBrowser/#/R-GGA-2404199 IGF1,2:IGF1R autophosphorylates IEA Gallus gallus 30616 R-GGA-2408551 https://reactome.org/PathwayBrowser/#/R-GGA-2408551 SeMet is converted to AdoSeMet by MAT IEA Gallus gallus 30616 R-GGA-2422927 https://reactome.org/PathwayBrowser/#/R-GGA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Gallus gallus 30616 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus 30616 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus 30616 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus 30616 R-GGA-2428926 https://reactome.org/PathwayBrowser/#/R-GGA-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Gallus gallus 30616 R-GGA-2430535 https://reactome.org/PathwayBrowser/#/R-GGA-2430535 MASTL phosphorylates ENSA IEA Gallus gallus 30616 R-GGA-2466068 https://reactome.org/PathwayBrowser/#/R-GGA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Gallus gallus 30616 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus 30616 R-GGA-2468293 https://reactome.org/PathwayBrowser/#/R-GGA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Gallus gallus 30616 R-GGA-2562526 https://reactome.org/PathwayBrowser/#/R-GGA-2562526 PLK1 phosphorylates OPTN IEA Gallus gallus 30616 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus 30616 R-GGA-2581474 https://reactome.org/PathwayBrowser/#/R-GGA-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Gallus gallus 30616 R-GGA-265682 https://reactome.org/PathwayBrowser/#/R-GGA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Gallus gallus 30616 R-GGA-265783 https://reactome.org/PathwayBrowser/#/R-GGA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Gallus gallus 30616 R-GGA-265936 https://reactome.org/PathwayBrowser/#/R-GGA-265936 Phosphorylation of RPA2 by CDC2 kinase TAS Gallus gallus 30616 R-GGA-265951 https://reactome.org/PathwayBrowser/#/R-GGA-265951 Phosphorylation of FANCG at S7 TAS Gallus gallus 30616 R-GGA-265959 https://reactome.org/PathwayBrowser/#/R-GGA-265959 Phosphorylation of Chk2 by ATM upon DNA damage TAS Gallus gallus 30616 R-GGA-265987 https://reactome.org/PathwayBrowser/#/R-GGA-265987 Phosphorylation of BRCA1 IEA Gallus gallus 30616 R-GGA-266082 https://reactome.org/PathwayBrowser/#/R-GGA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Gallus gallus 30616 R-GGA-2682349 https://reactome.org/PathwayBrowser/#/R-GGA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Gallus gallus 30616 R-GGA-2730841 https://reactome.org/PathwayBrowser/#/R-GGA-2730841 Phosphorylation and activation of VAV IEA Gallus gallus 30616 R-GGA-2730856 https://reactome.org/PathwayBrowser/#/R-GGA-2730856 Autophosphorylation of PAK IEA Gallus gallus 30616 R-GGA-2730858 https://reactome.org/PathwayBrowser/#/R-GGA-2730858 Autophosphorylation of BTK/ITK IEA Gallus gallus 30616 R-GGA-2730862 https://reactome.org/PathwayBrowser/#/R-GGA-2730862 Autophosphorylation of LYN kinase IEA Gallus gallus 30616 R-GGA-2730870 https://reactome.org/PathwayBrowser/#/R-GGA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Gallus gallus 30616 R-GGA-2730896 https://reactome.org/PathwayBrowser/#/R-GGA-2730896 Phosphorylation of MEK4 by MEKK1 IEA Gallus gallus 30616 R-GGA-2730900 https://reactome.org/PathwayBrowser/#/R-GGA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Gallus gallus 30616 R-GGA-2984220 https://reactome.org/PathwayBrowser/#/R-GGA-2984220 CDK1:CCNB phosphorylates NEK9 IEA Gallus gallus 30616 R-GGA-2984226 https://reactome.org/PathwayBrowser/#/R-GGA-2984226 PLK1 phosphorylates NEK9 IEA Gallus gallus 30616 R-GGA-2984258 https://reactome.org/PathwayBrowser/#/R-GGA-2984258 NEK9 phosphorylates NEK6/NEK7 IEA Gallus gallus 30616 R-GGA-2990833 https://reactome.org/PathwayBrowser/#/R-GGA-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Gallus gallus 30616 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus 30616 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus 30616 R-GGA-2993447 https://reactome.org/PathwayBrowser/#/R-GGA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Gallus gallus 30616 R-GGA-2993799 https://reactome.org/PathwayBrowser/#/R-GGA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Gallus gallus 30616 R-GGA-2993814 https://reactome.org/PathwayBrowser/#/R-GGA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Gallus gallus 30616 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus 30616 R-GGA-3000327 https://reactome.org/PathwayBrowser/#/R-GGA-3000327 PLK1 phosphorylates BORA IEA Gallus gallus 30616 R-GGA-3095901 https://reactome.org/PathwayBrowser/#/R-GGA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Gallus gallus 30616 R-GGA-3132737 https://reactome.org/PathwayBrowser/#/R-GGA-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Gallus gallus 30616 R-GGA-3159253 https://reactome.org/PathwayBrowser/#/R-GGA-3159253 MMAB adenosylates cob(I)alamin IEA Gallus gallus 30616 R-GGA-3228469 https://reactome.org/PathwayBrowser/#/R-GGA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Gallus gallus 30616 R-GGA-3229102 https://reactome.org/PathwayBrowser/#/R-GGA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Gallus gallus 30616 R-GGA-3238999 https://reactome.org/PathwayBrowser/#/R-GGA-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Gallus gallus 30616 R-GGA-3239019 https://reactome.org/PathwayBrowser/#/R-GGA-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Gallus gallus 30616 R-GGA-3371422 https://reactome.org/PathwayBrowser/#/R-GGA-3371422 ATP hydrolysis by HSP70 IEA Gallus gallus 30616 R-GGA-3371435 https://reactome.org/PathwayBrowser/#/R-GGA-3371435 Constitutive phosphorylation by GSK3 IEA Gallus gallus 30616 R-GGA-3371531 https://reactome.org/PathwayBrowser/#/R-GGA-3371531 Constitutive phosphorylation by pERK1/2 IEA Gallus gallus 30616 R-GGA-3371590 https://reactome.org/PathwayBrowser/#/R-GGA-3371590 HSP70 binds to HSP40:nascent protein IEA Gallus gallus 30616 R-GGA-349444 https://reactome.org/PathwayBrowser/#/R-GGA-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Gallus gallus 30616 R-GGA-351434 https://reactome.org/PathwayBrowser/#/R-GGA-351434 Phosphorylation of H2AX at S139 by ATM at the site of DSB TAS Gallus gallus 30616 R-GGA-351455 https://reactome.org/PathwayBrowser/#/R-GGA-351455 Phosphorylation of NBS1 by ATM TAS Gallus gallus 30616 R-GGA-352840 https://reactome.org/PathwayBrowser/#/R-GGA-352840 glucose + ATP => glucose 6-phosphate + ADP TAS Gallus gallus 30616 R-GGA-352908 https://reactome.org/PathwayBrowser/#/R-GGA-352908 fructose 6-phosphate + ATP => fructose 2,6-bisphosphate + ADP TAS Gallus gallus 30616 R-GGA-352945 https://reactome.org/PathwayBrowser/#/R-GGA-352945 fructose 6-phosphate + ATP => fructose 1,6-bisphosphate + ADP TAS Gallus gallus 30616 R-GGA-353023 https://reactome.org/PathwayBrowser/#/R-GGA-353023 3-phosphoglycerate + ATP <=> 1,3-bisphosphoglycerate + ADP TAS Gallus gallus 30616 R-GGA-353039 https://reactome.org/PathwayBrowser/#/R-GGA-353039 1,3-bisphosphoglycerate + ADP <=> 3-phosphoglycerate + ATP TAS Gallus gallus 30616 R-GGA-353056 https://reactome.org/PathwayBrowser/#/R-GGA-353056 phosphoenolpyruvate + ADP => pyruvate + ATP TAS Gallus gallus 30616 R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 30616 R-GGA-353455 https://reactome.org/PathwayBrowser/#/R-GGA-353455 Autophosphorylation of DNA-PKcs IEA Gallus gallus 30616 R-GGA-354073 https://reactome.org/PathwayBrowser/#/R-GGA-354073 Autophosphorylation of PTK2 at Y397 IEA Gallus gallus 30616 R-GGA-354124 https://reactome.org/PathwayBrowser/#/R-GGA-354124 Phosphorylation of pPTK2 by SRC IEA Gallus gallus 30616 R-GGA-372693 https://reactome.org/PathwayBrowser/#/R-GGA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Gallus gallus 30616 R-GGA-372977 https://reactome.org/PathwayBrowser/#/R-GGA-372977 succinylCoA + ADP + Pi <=> succinate + CoASH + ATP TAS Gallus gallus 30616 R-GGA-373134 https://reactome.org/PathwayBrowser/#/R-GGA-373134 succinate + CoASH + ATP <=> succinylCoA + ADP + Pi TAS Gallus gallus 30616 R-GGA-373750 https://reactome.org/PathwayBrowser/#/R-GGA-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Gallus gallus 30616 R-GGA-374701 https://reactome.org/PathwayBrowser/#/R-GGA-374701 Phosphorylation of DCC by Fyn IEA Gallus gallus 30616 R-GGA-3769394 https://reactome.org/PathwayBrowser/#/R-GGA-3769394 AKT phosphorylates CBY1 IEA Gallus gallus 30616 R-GGA-377186 https://reactome.org/PathwayBrowser/#/R-GGA-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Gallus gallus 30616 R-GGA-3772435 https://reactome.org/PathwayBrowser/#/R-GGA-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Gallus gallus 30616 R-GGA-3772436 https://reactome.org/PathwayBrowser/#/R-GGA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Gallus gallus 30616 R-GGA-377640 https://reactome.org/PathwayBrowser/#/R-GGA-377640 Autophosphorylation of SRC IEA Gallus gallus 30616 R-GGA-3788705 https://reactome.org/PathwayBrowser/#/R-GGA-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Gallus gallus 30616 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus 30616 R-GGA-380780 https://reactome.org/PathwayBrowser/#/R-GGA-380780 Activation of Src IEA Gallus gallus 30616 R-GGA-381091 https://reactome.org/PathwayBrowser/#/R-GGA-381091 IRE1 dimer autophosphorylates IEA Gallus gallus 30616 R-GGA-381111 https://reactome.org/PathwayBrowser/#/R-GGA-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Gallus gallus 30616 R-GGA-382560 https://reactome.org/PathwayBrowser/#/R-GGA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Gallus gallus 30616 R-GGA-382575 https://reactome.org/PathwayBrowser/#/R-GGA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Gallus gallus 30616 R-GGA-383190 https://reactome.org/PathwayBrowser/#/R-GGA-383190 HCO3- transport through ion channel IEA Gallus gallus 30616 R-GGA-3857329 https://reactome.org/PathwayBrowser/#/R-GGA-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Gallus gallus 30616 R-GGA-388831 https://reactome.org/PathwayBrowser/#/R-GGA-388831 Phosphorylation of CD28 IEA Gallus gallus 30616 R-GGA-389083 https://reactome.org/PathwayBrowser/#/R-GGA-389083 Autophosphorylation of PDGF alpha receptors IEA Gallus gallus 30616 R-GGA-389086 https://reactome.org/PathwayBrowser/#/R-GGA-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Gallus gallus 30616 R-GGA-389158 https://reactome.org/PathwayBrowser/#/R-GGA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-389354 https://reactome.org/PathwayBrowser/#/R-GGA-389354 Activation of Vav1 IEA Gallus gallus 30616 R-GGA-389622 https://reactome.org/PathwayBrowser/#/R-GGA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 30616 R-GGA-389632 https://reactome.org/PathwayBrowser/#/R-GGA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 30616 R-GGA-389652 https://reactome.org/PathwayBrowser/#/R-GGA-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Gallus gallus 30616 R-GGA-389756 https://reactome.org/PathwayBrowser/#/R-GGA-389756 AKT interacts and phosphorylates Cot IEA Gallus gallus 30616 R-GGA-389762 https://reactome.org/PathwayBrowser/#/R-GGA-389762 Phosphorylation of PD-1 IEA Gallus gallus 30616 R-GGA-390593 https://reactome.org/PathwayBrowser/#/R-GGA-390593 ATP Hydrolysis By Myosin IEA Gallus gallus 30616 R-GGA-390598 https://reactome.org/PathwayBrowser/#/R-GGA-390598 Myosin Binds ATP IEA Gallus gallus 30616 R-GGA-392300 https://reactome.org/PathwayBrowser/#/R-GGA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-392530 https://reactome.org/PathwayBrowser/#/R-GGA-392530 p-S400-Cot phosphorylates NIK IEA Gallus gallus 30616 R-GGA-3928578 https://reactome.org/PathwayBrowser/#/R-GGA-3928578 EPH receptors autophosphorylate IEA Gallus gallus 30616 R-GGA-3928593 https://reactome.org/PathwayBrowser/#/R-GGA-3928593 Sfks phosphorylate EfnB1 TAS Gallus gallus 30616 R-GGA-3928595 https://reactome.org/PathwayBrowser/#/R-GGA-3928595 N-WASP binds ARP2/3 and G-actin IEA Gallus gallus 30616 R-GGA-3928596 https://reactome.org/PathwayBrowser/#/R-GGA-3928596 Phosphorylation of ephexin1 TAS Gallus gallus 30616 R-GGA-3928604 https://reactome.org/PathwayBrowser/#/R-GGA-3928604 SFKs phosphorylate VAV2,3 IEA Gallus gallus 30616 R-GGA-3928620 https://reactome.org/PathwayBrowser/#/R-GGA-3928620 PAK1 autophosphorylates IEA Gallus gallus 30616 R-GGA-3928625 https://reactome.org/PathwayBrowser/#/R-GGA-3928625 PAKs autophosphorylate IEA Gallus gallus 30616 R-GGA-3928627 https://reactome.org/PathwayBrowser/#/R-GGA-3928627 EPHB phosphorylates TIAM1 IEA Gallus gallus 30616 R-GGA-3928640 https://reactome.org/PathwayBrowser/#/R-GGA-3928640 PAKs phosphorylate MLC IEA Gallus gallus 30616 R-GGA-3928654 https://reactome.org/PathwayBrowser/#/R-GGA-3928654 Clathrin internalises EPH:EFN complexes IEA Gallus gallus 30616 R-GGA-399939 https://reactome.org/PathwayBrowser/#/R-GGA-399939 Autophosphorylation of PAK IEA Gallus gallus 30616 R-GGA-399944 https://reactome.org/PathwayBrowser/#/R-GGA-399944 Phosphorylation of CRMPs by Cdk5 IEA Gallus gallus 30616 R-GGA-399947 https://reactome.org/PathwayBrowser/#/R-GGA-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Gallus gallus 30616 R-GGA-399951 https://reactome.org/PathwayBrowser/#/R-GGA-399951 Phosphorylation of CRMPs by GSK3beta IEA Gallus gallus 30616 R-GGA-399952 https://reactome.org/PathwayBrowser/#/R-GGA-399952 Phosphorylation of LIMK-1 by PAK IEA Gallus gallus 30616 R-GGA-399978 https://reactome.org/PathwayBrowser/#/R-GGA-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Gallus gallus 30616 R-GGA-4085028 https://reactome.org/PathwayBrowser/#/R-GGA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Gallus gallus 30616 R-GGA-4086410 https://reactome.org/PathwayBrowser/#/R-GGA-4086410 CDK1 phosphorylates BORA IEA Gallus gallus 30616 R-GGA-4088024 https://reactome.org/PathwayBrowser/#/R-GGA-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Gallus gallus 30616 R-GGA-4088134 https://reactome.org/PathwayBrowser/#/R-GGA-4088134 PLK1 phosphorylates FOXM1 IEA Gallus gallus 30616 R-GGA-4093332 https://reactome.org/PathwayBrowser/#/R-GGA-4093332 p-EPHB phosphorylates SDC2 IEA Gallus gallus 30616 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus 30616 R-GGA-416985 https://reactome.org/PathwayBrowser/#/R-GGA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Gallus gallus 30616 R-GGA-419144 https://reactome.org/PathwayBrowser/#/R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate TAS Gallus gallus 30616 R-GGA-419153 https://reactome.org/PathwayBrowser/#/R-GGA-419153 5-phosphoribosylamine + glycine + ATP <=> 5-phosphoribosylglycinamide (GAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 30616 R-GGA-419157 https://reactome.org/PathwayBrowser/#/R-GGA-419157 5'-phosphoribosylformylglycinamidine (FGAM) + ATP => 5'-phosphoribosyl-5-aminoimidazole (AIR) + ADP + orthophosphate TAS Gallus gallus 30616 R-GGA-419223 https://reactome.org/PathwayBrowser/#/R-GGA-419223 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 30616 R-GGA-419440 https://reactome.org/PathwayBrowser/#/R-GGA-419440 L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate IEA Gallus gallus 30616 R-GGA-419490 https://reactome.org/PathwayBrowser/#/R-GGA-419490 Binding of ATP to P2X receptors IEA Gallus gallus 30616 R-GGA-419644 https://reactome.org/PathwayBrowser/#/R-GGA-419644 Transphosphorylation of pLIMK1 IEA Gallus gallus 30616 R-GGA-419646 https://reactome.org/PathwayBrowser/#/R-GGA-419646 SEMA4D interacts with Plexin-B1:Met IEA Gallus gallus 30616 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus 30616 R-GGA-421218 https://reactome.org/PathwayBrowser/#/R-GGA-421218 xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate IEA Gallus gallus 30616 R-GGA-426240 https://reactome.org/PathwayBrowser/#/R-GGA-426240 DAG kinase produces phosphatidic acid from DAG IEA Gallus gallus 30616 R-GGA-428273 https://reactome.org/PathwayBrowser/#/R-GGA-428273 SPHK1 phosphorylates sphingoid IEA Gallus gallus 30616 R-GGA-428941 https://reactome.org/PathwayBrowser/#/R-GGA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Gallus gallus 30616 R-GGA-428961 https://reactome.org/PathwayBrowser/#/R-GGA-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Gallus gallus 30616 R-GGA-429016 https://reactome.org/PathwayBrowser/#/R-GGA-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Gallus gallus 30616 R-GGA-429157 https://reactome.org/PathwayBrowser/#/R-GGA-429157 ABCC4 accumulation of dense granule contents IEA Gallus gallus 30616 R-GGA-429441 https://reactome.org/PathwayBrowser/#/R-GGA-429441 SYK activation by SRC IEA Gallus gallus 30616 R-GGA-429449 https://reactome.org/PathwayBrowser/#/R-GGA-429449 Syk activation leads to SLP-76 activation IEA Gallus gallus 30616 R-GGA-432129 https://reactome.org/PathwayBrowser/#/R-GGA-432129 FGR binds and phosphorylates LRP8 IEA Gallus gallus 30616 R-GGA-432148 https://reactome.org/PathwayBrowser/#/R-GGA-432148 Fgr may phosphorylate p38 MAPK IEA Gallus gallus 30616 R-GGA-432232 https://reactome.org/PathwayBrowser/#/R-GGA-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Gallus gallus 30616 R-GGA-4332358 https://reactome.org/PathwayBrowser/#/R-GGA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Gallus gallus 30616 R-GGA-4332363 https://reactome.org/PathwayBrowser/#/R-GGA-4332363 Autophosphorylation and activation of CAMK2 IEA Gallus gallus 30616 R-GGA-433606 https://reactome.org/PathwayBrowser/#/R-GGA-433606 sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP IEA Gallus gallus 30616 R-GGA-433786 https://reactome.org/PathwayBrowser/#/R-GGA-433786 Phosphorylation of IRF3 by TBK1 complexed with activated TLR3 IEA Gallus gallus 30616 R-GGA-433804 https://reactome.org/PathwayBrowser/#/R-GGA-433804 IKK epsilon is recruited to the Viral dsRNA:TLR3:TICAM1 complex IEA Gallus gallus 30616 R-GGA-433826 https://reactome.org/PathwayBrowser/#/R-GGA-433826 Phosphorylation of IRF3 by IKK epsilon(IKBKE) complexed with activated TLR3. IEA Gallus gallus 30616 R-GGA-433845 https://reactome.org/PathwayBrowser/#/R-GGA-433845 chicken RIP1 facilitates IKKs complex activation IEA Gallus gallus 30616 R-GGA-433955 https://reactome.org/PathwayBrowser/#/R-GGA-433955 Phosphorylation of IKKs complex by activated TAK1 IEA Gallus gallus 30616 R-GGA-433957 https://reactome.org/PathwayBrowser/#/R-GGA-433957 Activation of recruited TAK1 IEA Gallus gallus 30616 R-GGA-433986 https://reactome.org/PathwayBrowser/#/R-GGA-433986 activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB IEA Gallus gallus 30616 R-GGA-434018 https://reactome.org/PathwayBrowser/#/R-GGA-434018 Autophosphorylation of chicken IRAK4 IEA Gallus gallus 30616 R-GGA-434030 https://reactome.org/PathwayBrowser/#/R-GGA-434030 TBK1 is recruited to the Viral dsRNA:TLR3:TICAM1 complex IEA Gallus gallus 30616 R-GGA-434047 https://reactome.org/PathwayBrowser/#/R-GGA-434047 phosphorylation of IRAK2 by activated IRAK4 IEA Gallus gallus 30616 R-GGA-434382 https://reactome.org/PathwayBrowser/#/R-GGA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Gallus gallus 30616 R-GGA-435244 https://reactome.org/PathwayBrowser/#/R-GGA-435244 PECAM1 is phosphorylated IEA Gallus gallus 30616 R-GGA-437162 https://reactome.org/PathwayBrowser/#/R-GGA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-437984 https://reactome.org/PathwayBrowser/#/R-GGA-437984 Phosphorylation of MKK3/MKK6 by activated TAK1 IEA Gallus gallus 30616 R-GGA-437999 https://reactome.org/PathwayBrowser/#/R-GGA-437999 Phosphorylation of MKK4 by activated TAK1 IEA Gallus gallus 30616 R-GGA-438005 https://reactome.org/PathwayBrowser/#/R-GGA-438005 MKK4 phosphorylates JNK IEA Gallus gallus 30616 R-GGA-438019 https://reactome.org/PathwayBrowser/#/R-GGA-438019 activated chicken MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Gallus gallus 30616 R-GGA-438026 https://reactome.org/PathwayBrowser/#/R-GGA-438026 Activation and dimerization of c-JUN in the nucleus IEA Gallus gallus 30616 R-GGA-4411383 https://reactome.org/PathwayBrowser/#/R-GGA-4411383 NLK phosphorylates TCF/LEF IEA Gallus gallus 30616 R-GGA-4411402 https://reactome.org/PathwayBrowser/#/R-GGA-4411402 Activation of NLK IEA Gallus gallus 30616 R-GGA-4420117 https://reactome.org/PathwayBrowser/#/R-GGA-4420117 VEGFR2 autophosphorylates IEA Gallus gallus 30616 R-GGA-4420121 https://reactome.org/PathwayBrowser/#/R-GGA-4420121 SFKs phosphorylate PLCG1 IEA Gallus gallus 30616 R-GGA-4420128 https://reactome.org/PathwayBrowser/#/R-GGA-4420128 SRC-1 phosphorylates SHB IEA Gallus gallus 30616 R-GGA-4420206 https://reactome.org/PathwayBrowser/#/R-GGA-4420206 Phosphorylation of SRC-1 IEA Gallus gallus 30616 R-GGA-442724 https://reactome.org/PathwayBrowser/#/R-GGA-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Gallus gallus 30616 R-GGA-442913 https://reactome.org/PathwayBrowser/#/R-GGA-442913 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Gallus gallus 30616 R-GGA-443818 https://reactome.org/PathwayBrowser/#/R-GGA-443818 Phosphorylation of L1 by EPHB2 TAS Gallus gallus 30616 R-GGA-445072 https://reactome.org/PathwayBrowser/#/R-GGA-445072 Interaction of PAK1 with Rac1-GTP IEA Gallus gallus 30616 R-GGA-445079 https://reactome.org/PathwayBrowser/#/R-GGA-445079 Phosphorylation of L1 by ERK IEA Gallus gallus 30616 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus 30616 R-GGA-445700 https://reactome.org/PathwayBrowser/#/R-GGA-445700 Myosin Binds ATP IEA Gallus gallus 30616 R-GGA-445813 https://reactome.org/PathwayBrowser/#/R-GGA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Gallus gallus 30616 R-GGA-446634 https://reactome.org/PathwayBrowser/#/R-GGA-446634 IRAK4 is activated by autophosphorylation IEA Gallus gallus 30616 R-GGA-447074 https://reactome.org/PathwayBrowser/#/R-GGA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Gallus gallus 30616 R-GGA-448955 https://reactome.org/PathwayBrowser/#/R-GGA-448955 Phosphorylation of MEF2 proteins by p38 IEA Gallus gallus 30616 R-GGA-449911 https://reactome.org/PathwayBrowser/#/R-GGA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Gallus gallus 30616 R-GGA-450088 https://reactome.org/PathwayBrowser/#/R-GGA-450088 GLUT1 tetramer binds 4xATP IEA Gallus gallus 30616 R-GGA-450092 https://reactome.org/PathwayBrowser/#/R-GGA-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Gallus gallus 30616 R-GGA-450222 https://reactome.org/PathwayBrowser/#/R-GGA-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Gallus gallus 30616 R-GGA-450325 https://reactome.org/PathwayBrowser/#/R-GGA-450325 c-FOS activation by phospho ERK1/2 IEA Gallus gallus 30616 R-GGA-450333 https://reactome.org/PathwayBrowser/#/R-GGA-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Gallus gallus 30616 R-GGA-450337 https://reactome.org/PathwayBrowser/#/R-GGA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Gallus gallus 30616 R-GGA-450346 https://reactome.org/PathwayBrowser/#/R-GGA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Gallus gallus 30616 R-GGA-450474 https://reactome.org/PathwayBrowser/#/R-GGA-450474 MK2 phosphorylates BRF1 IEA Gallus gallus 30616 R-GGA-450490 https://reactome.org/PathwayBrowser/#/R-GGA-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Gallus gallus 30616 R-GGA-450533 https://reactome.org/PathwayBrowser/#/R-GGA-450533 PKCdelta phosphorylates HuR IEA Gallus gallus 30616 R-GGA-450550 https://reactome.org/PathwayBrowser/#/R-GGA-450550 PKCalpha phosphorylates HuR IEA Gallus gallus 30616 R-GGA-451447 https://reactome.org/PathwayBrowser/#/R-GGA-451447 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 IEA Gallus gallus 30616 R-GGA-451516 https://reactome.org/PathwayBrowser/#/R-GGA-451516 activated MEK2 phosphorylates ERK2 IEA Gallus gallus 30616 R-GGA-4793911 https://reactome.org/PathwayBrowser/#/R-GGA-4793911 MAPKAPK2 phosphorylates HSF1 IEA Gallus gallus 30616 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 30616 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 30616 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 30616 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 30616 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 30616 R-GGA-504054 https://reactome.org/PathwayBrowser/#/R-GGA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Gallus gallus 30616 R-GGA-508040 https://reactome.org/PathwayBrowser/#/R-GGA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Gallus gallus 30616 R-GGA-5082387 https://reactome.org/PathwayBrowser/#/R-GGA-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Gallus gallus 30616 R-GGA-5082405 https://reactome.org/PathwayBrowser/#/R-GGA-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Gallus gallus 30616 R-GGA-508308 https://reactome.org/PathwayBrowser/#/R-GGA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Gallus gallus 30616 R-GGA-5218640 https://reactome.org/PathwayBrowser/#/R-GGA-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Gallus gallus 30616 R-GGA-5218642 https://reactome.org/PathwayBrowser/#/R-GGA-5218642 PTK2 autophosphorylates IEA Gallus gallus 30616 R-GGA-5218804 https://reactome.org/PathwayBrowser/#/R-GGA-5218804 p38 MAPK activation by VEGFR IEA Gallus gallus 30616 R-GGA-5218805 https://reactome.org/PathwayBrowser/#/R-GGA-5218805 PKC autophosphorylates IEA Gallus gallus 30616 R-GGA-5218806 https://reactome.org/PathwayBrowser/#/R-GGA-5218806 FYN autophosphorylates IEA Gallus gallus 30616 R-GGA-5218809 https://reactome.org/PathwayBrowser/#/R-GGA-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Gallus gallus 30616 R-GGA-5218812 https://reactome.org/PathwayBrowser/#/R-GGA-5218812 FYN phosphorylates PAK2 IEA Gallus gallus 30616 R-GGA-5218814 https://reactome.org/PathwayBrowser/#/R-GGA-5218814 PAK2 autophorylates IEA Gallus gallus 30616 R-GGA-5218819 https://reactome.org/PathwayBrowser/#/R-GGA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-5218820 https://reactome.org/PathwayBrowser/#/R-GGA-5218820 Src kinases phosphorylate VAV IEA Gallus gallus 30616 R-GGA-5218821 https://reactome.org/PathwayBrowser/#/R-GGA-5218821 PDK1 phosphorylates PKC IEA Gallus gallus 30616 R-GGA-5218823 https://reactome.org/PathwayBrowser/#/R-GGA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Gallus gallus 30616 R-GGA-5218826 https://reactome.org/PathwayBrowser/#/R-GGA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Gallus gallus 30616 R-GGA-5218830 https://reactome.org/PathwayBrowser/#/R-GGA-5218830 SRC-1 phosphorylates PTK2-beta IEA Gallus gallus 30616 R-GGA-5218845 https://reactome.org/PathwayBrowser/#/R-GGA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Gallus gallus 30616 R-GGA-5218851 https://reactome.org/PathwayBrowser/#/R-GGA-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Gallus gallus 30616 R-GGA-5218916 https://reactome.org/PathwayBrowser/#/R-GGA-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Gallus gallus 30616 R-GGA-5223313 https://reactome.org/PathwayBrowser/#/R-GGA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Gallus gallus 30616 R-GGA-5223317 https://reactome.org/PathwayBrowser/#/R-GGA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Gallus gallus 30616 R-GGA-5229343 https://reactome.org/PathwayBrowser/#/R-GGA-5229343 AXIN is phosphorylated in the destruction complex IEA Gallus gallus 30616 R-GGA-5251989 https://reactome.org/PathwayBrowser/#/R-GGA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Gallus gallus 30616 R-GGA-5339524 https://reactome.org/PathwayBrowser/#/R-GGA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus 30616 R-GGA-5357429 https://reactome.org/PathwayBrowser/#/R-GGA-5357429 AXL autophosphorylates on Y779 and Y821 IEA Gallus gallus 30616 R-GGA-5357472 https://reactome.org/PathwayBrowser/#/R-GGA-5357472 PAK1-3 autophosphorylates IEA Gallus gallus 30616 R-GGA-5357477 https://reactome.org/PathwayBrowser/#/R-GGA-5357477 PAK1-3 phosphorylates VE-cadherin IEA Gallus gallus 30616 R-GGA-5358475 https://reactome.org/PathwayBrowser/#/R-GGA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Gallus gallus 30616 R-GGA-5358510 https://reactome.org/PathwayBrowser/#/R-GGA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Gallus gallus 30616 R-GGA-5358518 https://reactome.org/PathwayBrowser/#/R-GGA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Gallus gallus 30616 R-GGA-5358592 https://reactome.org/PathwayBrowser/#/R-GGA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Gallus gallus 30616 R-GGA-5358597 https://reactome.org/PathwayBrowser/#/R-GGA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Gallus gallus 30616 R-GGA-5358599 https://reactome.org/PathwayBrowser/#/R-GGA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Gallus gallus 30616 R-GGA-5358912 https://reactome.org/PathwayBrowser/#/R-GGA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Gallus gallus 30616 R-GGA-5362459 https://reactome.org/PathwayBrowser/#/R-GGA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Gallus gallus 30616 R-GGA-548843 https://reactome.org/PathwayBrowser/#/R-GGA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Gallus gallus 30616 R-GGA-5603114 https://reactome.org/PathwayBrowser/#/R-GGA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Gallus gallus 30616 R-GGA-5607722 https://reactome.org/PathwayBrowser/#/R-GGA-5607722 Active NIK phosphorylates IKKA dimer IEA Gallus gallus 30616 R-GGA-5607726 https://reactome.org/PathwayBrowser/#/R-GGA-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Gallus gallus 30616 R-GGA-5607732 https://reactome.org/PathwayBrowser/#/R-GGA-5607732 K63polyUb-TAK1 autophosphorylates IEA Gallus gallus 30616 R-GGA-5607740 https://reactome.org/PathwayBrowser/#/R-GGA-5607740 PKC-delta phosphorylates CARD9 IEA Gallus gallus 30616 R-GGA-5610720 https://reactome.org/PathwayBrowser/#/R-GGA-5610720 PKA phosphorylates GLI3 IEA Gallus gallus 30616 R-GGA-5610722 https://reactome.org/PathwayBrowser/#/R-GGA-5610722 CK1 phosphorylates p-GLI3 IEA Gallus gallus 30616 R-GGA-5610727 https://reactome.org/PathwayBrowser/#/R-GGA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Gallus gallus 30616 R-GGA-5610732 https://reactome.org/PathwayBrowser/#/R-GGA-5610732 GSK3 phosphorylates p-GLI3 IEA Gallus gallus 30616 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 30616 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 30616 R-GGA-5618085 https://reactome.org/PathwayBrowser/#/R-GGA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Gallus gallus 30616 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 30616 R-GGA-5618098 https://reactome.org/PathwayBrowser/#/R-GGA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Gallus gallus 30616 R-GGA-5618099 https://reactome.org/PathwayBrowser/#/R-GGA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Gallus gallus 30616 R-GGA-5618105 https://reactome.org/PathwayBrowser/#/R-GGA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Gallus gallus 30616 R-GGA-5618107 https://reactome.org/PathwayBrowser/#/R-GGA-5618107 ATP binding to HSP90 triggers conformation change IEA Gallus gallus 30616 R-GGA-5618110 https://reactome.org/PathwayBrowser/#/R-GGA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Gallus gallus 30616 R-GGA-5623667 https://reactome.org/PathwayBrowser/#/R-GGA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Gallus gallus 30616 R-GGA-5624473 https://reactome.org/PathwayBrowser/#/R-GGA-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Gallus gallus 30616 R-GGA-5624486 https://reactome.org/PathwayBrowser/#/R-GGA-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Gallus gallus 30616 R-GGA-5624492 https://reactome.org/PathwayBrowser/#/R-GGA-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Gallus gallus 30616 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus 30616 R-GGA-5626507 https://reactome.org/PathwayBrowser/#/R-GGA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Gallus gallus 30616 R-GGA-5627775 https://reactome.org/PathwayBrowser/#/R-GGA-5627775 Autophosphorylation of PAK1,2,3 IEA Gallus gallus 30616 R-GGA-5654147 https://reactome.org/PathwayBrowser/#/R-GGA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Gallus gallus 30616 R-GGA-5654149 https://reactome.org/PathwayBrowser/#/R-GGA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Gallus gallus 30616 R-GGA-5654151 https://reactome.org/PathwayBrowser/#/R-GGA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Gallus gallus 30616 R-GGA-5654222 https://reactome.org/PathwayBrowser/#/R-GGA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Gallus gallus 30616 R-GGA-5654397 https://reactome.org/PathwayBrowser/#/R-GGA-5654397 Activated FGFR2 phosphorylates FRS2 IEA Gallus gallus 30616 R-GGA-5654407 https://reactome.org/PathwayBrowser/#/R-GGA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Gallus gallus 30616 R-GGA-5654408 https://reactome.org/PathwayBrowser/#/R-GGA-5654408 Activated FGFR3 phosphorylates FRS2 IEA Gallus gallus 30616 R-GGA-5654418 https://reactome.org/PathwayBrowser/#/R-GGA-5654418 Activated FGFR4 phosphorylates FRS2 IEA Gallus gallus 30616 R-GGA-5654428 https://reactome.org/PathwayBrowser/#/R-GGA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Gallus gallus 30616 R-GGA-5654560 https://reactome.org/PathwayBrowser/#/R-GGA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Gallus gallus 30616 R-GGA-5654562 https://reactome.org/PathwayBrowser/#/R-GGA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Gallus gallus 30616 R-GGA-5654565 https://reactome.org/PathwayBrowser/#/R-GGA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Gallus gallus 30616 R-GGA-5654566 https://reactome.org/PathwayBrowser/#/R-GGA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Gallus gallus 30616 R-GGA-5654575 https://reactome.org/PathwayBrowser/#/R-GGA-5654575 Activated FGFR1 phosphorylates FRS2 IEA Gallus gallus 30616 R-GGA-5654578 https://reactome.org/PathwayBrowser/#/R-GGA-5654578 Activated FGFR1 phosphorylates FRS3 IEA Gallus gallus 30616 R-GGA-5654582 https://reactome.org/PathwayBrowser/#/R-GGA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Gallus gallus 30616 R-GGA-5654587 https://reactome.org/PathwayBrowser/#/R-GGA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Gallus gallus 30616 R-GGA-5654605 https://reactome.org/PathwayBrowser/#/R-GGA-5654605 Activated FGFR2 phosphorylates FRS3 IEA Gallus gallus 30616 R-GGA-5654607 https://reactome.org/PathwayBrowser/#/R-GGA-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Gallus gallus 30616 R-GGA-5654628 https://reactome.org/PathwayBrowser/#/R-GGA-5654628 Activated FGFR3 phosphorylates FRS3 IEA Gallus gallus 30616 R-GGA-5654631 https://reactome.org/PathwayBrowser/#/R-GGA-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Gallus gallus 30616 R-GGA-5654634 https://reactome.org/PathwayBrowser/#/R-GGA-5654634 Activated FGFR3 phosphorylates SHC1 IEA Gallus gallus 30616 R-GGA-5654653 https://reactome.org/PathwayBrowser/#/R-GGA-5654653 Activated FGFR4 phosphorylates FRS3 IEA Gallus gallus 30616 R-GGA-5654655 https://reactome.org/PathwayBrowser/#/R-GGA-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Gallus gallus 30616 R-GGA-5654690 https://reactome.org/PathwayBrowser/#/R-GGA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-5654692 https://reactome.org/PathwayBrowser/#/R-GGA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-5654697 https://reactome.org/PathwayBrowser/#/R-GGA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-5654701 https://reactome.org/PathwayBrowser/#/R-GGA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-5654705 https://reactome.org/PathwayBrowser/#/R-GGA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-5654709 https://reactome.org/PathwayBrowser/#/R-GGA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-5654714 https://reactome.org/PathwayBrowser/#/R-GGA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-5654717 https://reactome.org/PathwayBrowser/#/R-GGA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 30616 R-GGA-5654989 https://reactome.org/PathwayBrowser/#/R-GGA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Gallus gallus 30616 R-GGA-5662466 https://reactome.org/PathwayBrowser/#/R-GGA-5662466 XYLB phosphorylates D-xylulose IEA Gallus gallus 30616 R-GGA-5665802 https://reactome.org/PathwayBrowser/#/R-GGA-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Gallus gallus 30616 R-GGA-5665868 https://reactome.org/PathwayBrowser/#/R-GGA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Gallus gallus 30616 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus 30616 R-GGA-5668545 https://reactome.org/PathwayBrowser/#/R-GGA-5668545 NIK autophosphorylates on T559 IEA Gallus gallus 30616 R-GGA-5668932 https://reactome.org/PathwayBrowser/#/R-GGA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Gallus gallus 30616 R-GGA-5668947 https://reactome.org/PathwayBrowser/#/R-GGA-5668947 PAK1 phosphorylates myosin phosphatase IEA Gallus gallus 30616 R-GGA-5668984 https://reactome.org/PathwayBrowser/#/R-GGA-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Gallus gallus 30616 R-GGA-5672008 https://reactome.org/PathwayBrowser/#/R-GGA-5672008 Thr-180 of ULK1 is phosphorylated IEA Gallus gallus 30616 R-GGA-5672010 https://reactome.org/PathwayBrowser/#/R-GGA-5672010 Active MTORC1 phosphorylates ULK1 IEA Gallus gallus 30616 R-GGA-5672012 https://reactome.org/PathwayBrowser/#/R-GGA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Gallus gallus 30616 R-GGA-5672828 https://reactome.org/PathwayBrowser/#/R-GGA-5672828 mTORC1 phosphorylates AKT1S1 IEA Gallus gallus 30616 R-GGA-5672969 https://reactome.org/PathwayBrowser/#/R-GGA-5672969 Phosphorylation of RAF IEA Gallus gallus 30616 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 30616 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 30616 R-GGA-5673768 https://reactome.org/PathwayBrowser/#/R-GGA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Gallus gallus 30616 R-GGA-5674373 https://reactome.org/PathwayBrowser/#/R-GGA-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Gallus gallus 30616 R-GGA-5675194 https://reactome.org/PathwayBrowser/#/R-GGA-5675194 Activated MAPK phosphorylates RAF1 IEA Gallus gallus 30616 R-GGA-5675198 https://reactome.org/PathwayBrowser/#/R-GGA-5675198 Activated MAPKs phosphorylate BRAF IEA Gallus gallus 30616 R-GGA-5675868 https://reactome.org/PathwayBrowser/#/R-GGA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Gallus gallus 30616 R-GGA-5678706 https://reactome.org/PathwayBrowser/#/R-GGA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Gallus gallus 30616 R-GGA-5678863 https://reactome.org/PathwayBrowser/#/R-GGA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Gallus gallus 30616 R-GGA-5679041 https://reactome.org/PathwayBrowser/#/R-GGA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Gallus gallus 30616 R-GGA-5679205 https://reactome.org/PathwayBrowser/#/R-GGA-5679205 ULK1 phosphorylates Beclin-1 IEA Gallus gallus 30616 R-GGA-5682026 https://reactome.org/PathwayBrowser/#/R-GGA-5682026 MRN bound to shortened telomeres activates ATM IEA Gallus gallus 30616 R-GGA-5682101 https://reactome.org/PathwayBrowser/#/R-GGA-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Gallus gallus 30616 R-GGA-5682285 https://reactome.org/PathwayBrowser/#/R-GGA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Gallus gallus 30616 R-GGA-5682598 https://reactome.org/PathwayBrowser/#/R-GGA-5682598 ATM phosphorylates HERC2 IEA Gallus gallus 30616 R-GGA-5682983 https://reactome.org/PathwayBrowser/#/R-GGA-5682983 ATM phosphorylates WHSC1 IEA Gallus gallus 30616 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus 30616 R-GGA-5683714 https://reactome.org/PathwayBrowser/#/R-GGA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Gallus gallus 30616 R-GGA-5683792 https://reactome.org/PathwayBrowser/#/R-GGA-5683792 p-T68-CHEK2 autophosphorylates IEA Gallus gallus 30616 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus 30616 R-GGA-5683930 https://reactome.org/PathwayBrowser/#/R-GGA-5683930 WICH phosphorylates H2AFX on Y142 IEA Gallus gallus 30616 R-GGA-5683964 https://reactome.org/PathwayBrowser/#/R-GGA-5683964 ATM phosphorylates EYA1-4 IEA Gallus gallus 30616 R-GGA-5684096 https://reactome.org/PathwayBrowser/#/R-GGA-5684096 CDK2 phosphorylates RBBP8 IEA Gallus gallus 30616 R-GGA-5684140 https://reactome.org/PathwayBrowser/#/R-GGA-5684140 ATM phosphorylates RBBP8 IEA Gallus gallus 30616 R-GGA-5684261 https://reactome.org/PathwayBrowser/#/R-GGA-5684261 MAP3K8 is phosphorylated IEA Gallus gallus 30616 R-GGA-5685156 https://reactome.org/PathwayBrowser/#/R-GGA-5685156 ATR phosphorylates RPA2 IEA Gallus gallus 30616 R-GGA-5686578 https://reactome.org/PathwayBrowser/#/R-GGA-5686578 Activated ATM phosphorylates ABL1 IEA Gallus gallus 30616 R-GGA-5686587 https://reactome.org/PathwayBrowser/#/R-GGA-5686587 ABL1 phosphorylates RAD52 IEA Gallus gallus 30616 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus 30616 R-GGA-5687086 https://reactome.org/PathwayBrowser/#/R-GGA-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Gallus gallus 30616 R-GGA-5687088 https://reactome.org/PathwayBrowser/#/R-GGA-5687088 PKA phosphorylates MAPKAPK5 IEA Gallus gallus 30616 R-GGA-5687090 https://reactome.org/PathwayBrowser/#/R-GGA-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Gallus gallus 30616 R-GGA-5687094 https://reactome.org/PathwayBrowser/#/R-GGA-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Gallus gallus 30616 R-GGA-5687101 https://reactome.org/PathwayBrowser/#/R-GGA-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Gallus gallus 30616 R-GGA-5687121 https://reactome.org/PathwayBrowser/#/R-GGA-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Gallus gallus 30616 R-GGA-5687183 https://reactome.org/PathwayBrowser/#/R-GGA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Gallus gallus 30616 R-GGA-5690250 https://reactome.org/PathwayBrowser/#/R-GGA-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Gallus gallus 30616 R-GGA-5690996 https://reactome.org/PathwayBrowser/#/R-GGA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Gallus gallus 30616 R-GGA-5692462 https://reactome.org/PathwayBrowser/#/R-GGA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Gallus gallus 30616 R-GGA-5692480 https://reactome.org/PathwayBrowser/#/R-GGA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Gallus gallus 30616 R-GGA-5692755 https://reactome.org/PathwayBrowser/#/R-GGA-5692755 CDK1 phosphorylates MAPK6 IEA Gallus gallus 30616 R-GGA-5692768 https://reactome.org/PathwayBrowser/#/R-GGA-5692768 MAPKAPK5 phosphorylates KALRN IEA Gallus gallus 30616 R-GGA-5692775 https://reactome.org/PathwayBrowser/#/R-GGA-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Gallus gallus 30616 R-GGA-5692779 https://reactome.org/PathwayBrowser/#/R-GGA-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Gallus gallus 30616 R-GGA-5693536 https://reactome.org/PathwayBrowser/#/R-GGA-5693536 ATM phosphorylates MDC1 IEA Gallus gallus 30616 R-GGA-5693540 https://reactome.org/PathwayBrowser/#/R-GGA-5693540 MRN activates ATM IEA Gallus gallus 30616 R-GGA-5693549 https://reactome.org/PathwayBrowser/#/R-GGA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Gallus gallus 30616 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus 30616 R-GGA-5693575 https://reactome.org/PathwayBrowser/#/R-GGA-5693575 DNA-PKcs autophosphorylates IEA Gallus gallus 30616 R-GGA-5693598 https://reactome.org/PathwayBrowser/#/R-GGA-5693598 ATM phosphorylates NBN IEA Gallus gallus 30616 R-GGA-5694425 https://reactome.org/PathwayBrowser/#/R-GGA-5694425 NSF ATPase activity dissociates cis-SNARE IEA Gallus gallus 30616 R-GGA-5694494 https://reactome.org/PathwayBrowser/#/R-GGA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Gallus gallus 30616 R-GGA-5695957 https://reactome.org/PathwayBrowser/#/R-GGA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Gallus gallus 30616 R-GGA-5696004 https://reactome.org/PathwayBrowser/#/R-GGA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Gallus gallus 30616 R-GGA-5696074 https://reactome.org/PathwayBrowser/#/R-GGA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Gallus gallus 30616 R-GGA-5696839 https://reactome.org/PathwayBrowser/#/R-GGA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Gallus gallus 30616 R-GGA-571316 https://reactome.org/PathwayBrowser/#/R-GGA-571316 Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. IEA Gallus gallus 30616 R-GGA-571327 https://reactome.org/PathwayBrowser/#/R-GGA-571327 IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex IEA Gallus gallus 30616 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus 30616 R-GGA-6784006 https://reactome.org/PathwayBrowser/#/R-GGA-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Gallus gallus 30616 R-GGA-6784319 https://reactome.org/PathwayBrowser/#/R-GGA-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Gallus gallus 30616 R-GGA-6784324 https://reactome.org/PathwayBrowser/#/R-GGA-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Gallus gallus 30616 R-GGA-6786050 https://reactome.org/PathwayBrowser/#/R-GGA-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Gallus gallus 30616 R-GGA-6786095 https://reactome.org/PathwayBrowser/#/R-GGA-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Gallus gallus 30616 R-GGA-6786096 https://reactome.org/PathwayBrowser/#/R-GGA-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Gallus gallus 30616 R-GGA-6786245 https://reactome.org/PathwayBrowser/#/R-GGA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Gallus gallus 30616 R-GGA-6788392 https://reactome.org/PathwayBrowser/#/R-GGA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Gallus gallus 30616 R-GGA-6788582 https://reactome.org/PathwayBrowser/#/R-GGA-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Gallus gallus 30616 R-GGA-6788798 https://reactome.org/PathwayBrowser/#/R-GGA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 30616 R-GGA-6788810 https://reactome.org/PathwayBrowser/#/R-GGA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 30616 R-GGA-6788855 https://reactome.org/PathwayBrowser/#/R-GGA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Gallus gallus 30616 R-GGA-6788867 https://reactome.org/PathwayBrowser/#/R-GGA-6788867 FN3K phosphorylates ketosamines IEA Gallus gallus 30616 R-GGA-6793661 https://reactome.org/PathwayBrowser/#/R-GGA-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Gallus gallus 30616 R-GGA-6795290 https://reactome.org/PathwayBrowser/#/R-GGA-6795290 TORC2 complex phosphorylates SGK1 IEA Gallus gallus 30616 R-GGA-6795460 https://reactome.org/PathwayBrowser/#/R-GGA-6795460 SGK1 phosphorylates MDM2 IEA Gallus gallus 30616 R-GGA-6795473 https://reactome.org/PathwayBrowser/#/R-GGA-6795473 PDPK1 phosphorylates SGK1 IEA Gallus gallus 30616 R-GGA-6797606 https://reactome.org/PathwayBrowser/#/R-GGA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Gallus gallus 30616 R-GGA-6798174 https://reactome.org/PathwayBrowser/#/R-GGA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Gallus gallus 30616 R-GGA-6798372 https://reactome.org/PathwayBrowser/#/R-GGA-6798372 ATM phosphorylates DYRK2 IEA Gallus gallus 30616 R-GGA-6799097 https://reactome.org/PathwayBrowser/#/R-GGA-6799097 ATM phosphorylates ZNF420 IEA Gallus gallus 30616 R-GGA-6799495 https://reactome.org/PathwayBrowser/#/R-GGA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Gallus gallus 30616 R-GGA-6801342 https://reactome.org/PathwayBrowser/#/R-GGA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Gallus gallus 30616 R-GGA-6801456 https://reactome.org/PathwayBrowser/#/R-GGA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Gallus gallus 30616 R-GGA-6801666 https://reactome.org/PathwayBrowser/#/R-GGA-6801666 PLK2 phosphorylates CENPJ IEA Gallus gallus 30616 R-GGA-6801675 https://reactome.org/PathwayBrowser/#/R-GGA-6801675 PLK2 phosphorylates NPM1 IEA Gallus gallus 30616 R-GGA-6803545 https://reactome.org/PathwayBrowser/#/R-GGA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Gallus gallus 30616 R-GGA-6803771 https://reactome.org/PathwayBrowser/#/R-GGA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Gallus gallus 30616 R-GGA-6804596 https://reactome.org/PathwayBrowser/#/R-GGA-6804596 APAF1:CYCS binds APIP IEA Gallus gallus 30616 R-GGA-6804955 https://reactome.org/PathwayBrowser/#/R-GGA-6804955 ATM phosphorylates MDM2 IEA Gallus gallus 30616 R-GGA-6805640 https://reactome.org/PathwayBrowser/#/R-GGA-6805640 AKT phosphorylates KAT6A IEA Gallus gallus 30616 R-GGA-6805785 https://reactome.org/PathwayBrowser/#/R-GGA-6805785 AKT phosphorylates PHF20 IEA Gallus gallus 30616 R-GGA-6806877 https://reactome.org/PathwayBrowser/#/R-GGA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Gallus gallus 30616 R-GGA-6806967 https://reactome.org/PathwayBrowser/#/R-GGA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Gallus gallus 30616 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 30616 R-GGA-6807868 https://reactome.org/PathwayBrowser/#/R-GGA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Gallus gallus 30616 R-GGA-6809015 https://reactome.org/PathwayBrowser/#/R-GGA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Gallus gallus 30616 R-GGA-6810233 https://reactome.org/PathwayBrowser/#/R-GGA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Gallus gallus 30616 R-GGA-6811422 https://reactome.org/PathwayBrowser/#/R-GGA-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Gallus gallus 30616 R-GGA-6811522 https://reactome.org/PathwayBrowser/#/R-GGA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Gallus gallus 30616 R-GGA-6814120 https://reactome.org/PathwayBrowser/#/R-GGA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Gallus gallus 30616 R-GGA-6814124 https://reactome.org/PathwayBrowser/#/R-GGA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Gallus gallus 30616 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus 30616 R-GGA-6814670 https://reactome.org/PathwayBrowser/#/R-GGA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Gallus gallus 30616 R-GGA-6814675 https://reactome.org/PathwayBrowser/#/R-GGA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Gallus gallus 30616 R-GGA-6814683 https://reactome.org/PathwayBrowser/#/R-GGA-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Gallus gallus 30616 R-GGA-68610 https://reactome.org/PathwayBrowser/#/R-GGA-68610 Formation of ORC(2-5) complex IEA Gallus gallus 30616 R-GGA-68944 https://reactome.org/PathwayBrowser/#/R-GGA-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Gallus gallus 30616 R-GGA-68954 https://reactome.org/PathwayBrowser/#/R-GGA-68954 Mcm2-7 is phosphorylated by DDK IEA Gallus gallus 30616 R-GGA-69005 https://reactome.org/PathwayBrowser/#/R-GGA-69005 Cdc6 protein is phosphorylated by CDK IEA Gallus gallus 30616 R-GGA-69015 https://reactome.org/PathwayBrowser/#/R-GGA-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Gallus gallus 30616 R-GGA-69063 https://reactome.org/PathwayBrowser/#/R-GGA-69063 Loading of PCNA - Sliding Clamp Formation IEA Gallus gallus 30616 R-GGA-69195 https://reactome.org/PathwayBrowser/#/R-GGA-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Gallus gallus 30616 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 30616 R-GGA-69608 https://reactome.org/PathwayBrowser/#/R-GGA-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Gallus gallus 30616 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus 30616 R-GGA-70333 https://reactome.org/PathwayBrowser/#/R-GGA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Gallus gallus 30616 R-GGA-70349 https://reactome.org/PathwayBrowser/#/R-GGA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Gallus gallus 30616 R-GGA-70355 https://reactome.org/PathwayBrowser/#/R-GGA-70355 GALK1 phosphorylates Gal to Gal1P IEA Gallus gallus 30616 R-GGA-70420 https://reactome.org/PathwayBrowser/#/R-GGA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Gallus gallus 30616 R-GGA-70467 https://reactome.org/PathwayBrowser/#/R-GGA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Gallus gallus 30616 R-GGA-70486 https://reactome.org/PathwayBrowser/#/R-GGA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Gallus gallus 30616 R-GGA-70555 https://reactome.org/PathwayBrowser/#/R-GGA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Gallus gallus 30616 R-GGA-70577 https://reactome.org/PathwayBrowser/#/R-GGA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Gallus gallus 30616 R-GGA-70599 https://reactome.org/PathwayBrowser/#/R-GGA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Gallus gallus 30616 R-GGA-70606 https://reactome.org/PathwayBrowser/#/R-GGA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Gallus gallus 30616 R-GGA-70773 https://reactome.org/PathwayBrowser/#/R-GGA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Gallus gallus 30616 R-GGA-70997 https://reactome.org/PathwayBrowser/#/R-GGA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Gallus gallus 30616 R-GGA-71031 https://reactome.org/PathwayBrowser/#/R-GGA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Gallus gallus 30616 R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus 30616 R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 30616 R-GGA-71735 https://reactome.org/PathwayBrowser/#/R-GGA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Gallus gallus 30616 R-GGA-71802 https://reactome.org/PathwayBrowser/#/R-GGA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Gallus gallus 30616 R-GGA-71850 https://reactome.org/PathwayBrowser/#/R-GGA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Gallus gallus 30616 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus 30616 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus 30616 R-GGA-727819 https://reactome.org/PathwayBrowser/#/R-GGA-727819 TAK1 phosphorylates MKK6 IEA Gallus gallus 30616 R-GGA-73548 https://reactome.org/PathwayBrowser/#/R-GGA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Gallus gallus 30616 R-GGA-73580 https://reactome.org/PathwayBrowser/#/R-GGA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Gallus gallus 30616 R-GGA-73598 https://reactome.org/PathwayBrowser/#/R-GGA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Gallus gallus 30616 R-GGA-73599 https://reactome.org/PathwayBrowser/#/R-GGA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Gallus gallus 30616 R-GGA-73632 https://reactome.org/PathwayBrowser/#/R-GGA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Gallus gallus 30616 R-GGA-73635 https://reactome.org/PathwayBrowser/#/R-GGA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Gallus gallus 30616 R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus 30616 R-GGA-73788 https://reactome.org/PathwayBrowser/#/R-GGA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Gallus gallus 30616 R-GGA-73792 https://reactome.org/PathwayBrowser/#/R-GGA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Gallus gallus 30616 R-GGA-73805 https://reactome.org/PathwayBrowser/#/R-GGA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Gallus gallus 30616 R-GGA-73810 https://reactome.org/PathwayBrowser/#/R-GGA-73810 FGAM + ATP => AIR + ADP + Pi IEA Gallus gallus 30616 R-GGA-73814 https://reactome.org/PathwayBrowser/#/R-GGA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Gallus gallus 30616 R-GGA-74220 https://reactome.org/PathwayBrowser/#/R-GGA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Gallus gallus 30616 R-GGA-74711 https://reactome.org/PathwayBrowser/#/R-GGA-74711 Phosphorylation of IRS IEA Gallus gallus 30616 R-GGA-74715 https://reactome.org/PathwayBrowser/#/R-GGA-74715 Autophosphorylation of insulin receptor IEA Gallus gallus 30616 R-GGA-74742 https://reactome.org/PathwayBrowser/#/R-GGA-74742 Phosphorylation of SHC1 IEA Gallus gallus 30616 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 30616 R-GGA-75125 https://reactome.org/PathwayBrowser/#/R-GGA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Gallus gallus 30616 R-GGA-75126 https://reactome.org/PathwayBrowser/#/R-GGA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Gallus gallus 30616 R-GGA-75848 https://reactome.org/PathwayBrowser/#/R-GGA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Gallus gallus 30616 R-GGA-75851 https://reactome.org/PathwayBrowser/#/R-GGA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Gallus gallus 30616 R-GGA-75887 https://reactome.org/PathwayBrowser/#/R-GGA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Gallus gallus 30616 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus 30616 R-GGA-77071 https://reactome.org/PathwayBrowser/#/R-GGA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Gallus gallus 30616 R-GGA-844438 https://reactome.org/PathwayBrowser/#/R-GGA-844438 NLRP1 oligomerizes IEA Gallus gallus 30616 R-GGA-873918 https://reactome.org/PathwayBrowser/#/R-GGA-873918 Transphosphorylation of JAK1 IEA Gallus gallus 30616 R-GGA-873919 https://reactome.org/PathwayBrowser/#/R-GGA-873919 Phosphorylation of JAK2 IEA Gallus gallus 30616 R-GGA-873922 https://reactome.org/PathwayBrowser/#/R-GGA-873922 Phosphorylation of STAT1 by JAK kinases IEA Gallus gallus 30616 R-GGA-873924 https://reactome.org/PathwayBrowser/#/R-GGA-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Gallus gallus 30616 R-GGA-877187 https://reactome.org/PathwayBrowser/#/R-GGA-877187 P2X7 mediates loss of intracellular K+ IEA Gallus gallus 30616 R-GGA-877198 https://reactome.org/PathwayBrowser/#/R-GGA-877198 P2X7 mediates membrane pores that include pannexin-1 IEA Gallus gallus 30616 R-GGA-879222 https://reactome.org/PathwayBrowser/#/R-GGA-879222 MDP:NLRP1 binds ATP IEA Gallus gallus 30616 R-GGA-879907 https://reactome.org/PathwayBrowser/#/R-GGA-879907 Tyrosine kinases phosphorylate the receptor IEA Gallus gallus 30616 R-GGA-879909 https://reactome.org/PathwayBrowser/#/R-GGA-879909 Activation of STAT5a/b by JAK2 IEA Gallus gallus 30616 R-GGA-879910 https://reactome.org/PathwayBrowser/#/R-GGA-879910 JAK2 is phosphorylated, activated IEA Gallus gallus 30616 R-GGA-8847638 https://reactome.org/PathwayBrowser/#/R-GGA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Gallus gallus 30616 R-GGA-8847977 https://reactome.org/PathwayBrowser/#/R-GGA-8847977 FRK phosphorylates PTEN IEA Gallus gallus 30616 R-GGA-8848053 https://reactome.org/PathwayBrowser/#/R-GGA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Gallus gallus 30616 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus 30616 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 30616 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 30616 R-GGA-8851797 https://reactome.org/PathwayBrowser/#/R-GGA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Gallus gallus 30616 R-GGA-8851890 https://reactome.org/PathwayBrowser/#/R-GGA-8851890 MET phosphorylates SHC1-2 IEA Gallus gallus 30616 R-GGA-8851933 https://reactome.org/PathwayBrowser/#/R-GGA-8851933 MET phosphorylates GAB1 IEA Gallus gallus 30616 R-GGA-8852019 https://reactome.org/PathwayBrowser/#/R-GGA-8852019 MET bound PI3K generates PIP3 IEA Gallus gallus 30616 R-GGA-8852128 https://reactome.org/PathwayBrowser/#/R-GGA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Gallus gallus 30616 R-GGA-8852131 https://reactome.org/PathwayBrowser/#/R-GGA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Gallus gallus 30616 R-GGA-8852132 https://reactome.org/PathwayBrowser/#/R-GGA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Gallus gallus 30616 R-GGA-8852134 https://reactome.org/PathwayBrowser/#/R-GGA-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Gallus gallus 30616 R-GGA-8852317 https://reactome.org/PathwayBrowser/#/R-GGA-8852317 PLK1 phosphorylates GTSE1 IEA Gallus gallus 30616 R-GGA-8852552 https://reactome.org/PathwayBrowser/#/R-GGA-8852552 MST1R autophosphorylates IEA Gallus gallus 30616 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus 30616 R-GGA-8853444 https://reactome.org/PathwayBrowser/#/R-GGA-8853444 AURKA phosphorylates PHLDA1 IEA Gallus gallus 30616 R-GGA-8853774 https://reactome.org/PathwayBrowser/#/R-GGA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Gallus gallus 30616 R-GGA-8853792 https://reactome.org/PathwayBrowser/#/R-GGA-8853792 RET tyrosine phosphorylation IEA Gallus gallus 30616 R-GGA-8855237 https://reactome.org/PathwayBrowser/#/R-GGA-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Gallus gallus 30616 R-GGA-8856813 https://reactome.org/PathwayBrowser/#/R-GGA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Gallus gallus 30616 R-GGA-8857555 https://reactome.org/PathwayBrowser/#/R-GGA-8857555 EGFR phosphorylates GPNMB IEA Gallus gallus 30616 R-GGA-8857577 https://reactome.org/PathwayBrowser/#/R-GGA-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Gallus gallus 30616 R-GGA-8857583 https://reactome.org/PathwayBrowser/#/R-GGA-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Gallus gallus 30616 R-GGA-8866542 https://reactome.org/PathwayBrowser/#/R-GGA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Gallus gallus 30616 R-GGA-8867041 https://reactome.org/PathwayBrowser/#/R-GGA-8867041 EGFR phosphorylates EPS15 IEA Gallus gallus 30616 R-GGA-8868066 https://reactome.org/PathwayBrowser/#/R-GGA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Gallus gallus 30616 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus 30616 R-GGA-8868118 https://reactome.org/PathwayBrowser/#/R-GGA-8868118 MAPK12 phosphorylates PTPN3 IEA Gallus gallus 30616 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus 30616 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus 30616 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus 30616 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus 30616 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus 30616 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus 30616 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus 30616 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus 30616 R-GGA-8869606 https://reactome.org/PathwayBrowser/#/R-GGA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Gallus gallus 30616 R-GGA-8869607 https://reactome.org/PathwayBrowser/#/R-GGA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Gallus gallus 30616 R-GGA-8869627 https://reactome.org/PathwayBrowser/#/R-GGA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Gallus gallus 30616 R-GGA-8869633 https://reactome.org/PathwayBrowser/#/R-GGA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Gallus gallus 30616 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus 30616 R-GGA-8871373 https://reactome.org/PathwayBrowser/#/R-GGA-8871373 BMX phosphorylates RUFY1 IEA Gallus gallus 30616 R-GGA-8874078 https://reactome.org/PathwayBrowser/#/R-GGA-8874078 PTK2 autophosphorylates IEA Gallus gallus 30616 R-GGA-8874080 https://reactome.org/PathwayBrowser/#/R-GGA-8874080 SRC phosphorylates PTK2 IEA Gallus gallus 30616 R-GGA-8874082 https://reactome.org/PathwayBrowser/#/R-GGA-8874082 MET phosphorylates PTK2 IEA Gallus gallus 30616 R-GGA-8875071 https://reactome.org/PathwayBrowser/#/R-GGA-8875071 ACSS3 ligates CoA to CH3COO- IEA Gallus gallus 30616 R-GGA-8875451 https://reactome.org/PathwayBrowser/#/R-GGA-8875451 MET phosphorylates CBL IEA Gallus gallus 30616 R-GGA-8875817 https://reactome.org/PathwayBrowser/#/R-GGA-8875817 MET phosphorylates STAT3 IEA Gallus gallus 30616 R-GGA-8876446 https://reactome.org/PathwayBrowser/#/R-GGA-8876446 p-ULK1 phosphorylates DENND3 IEA Gallus gallus 30616 R-GGA-8877691 https://reactome.org/PathwayBrowser/#/R-GGA-8877691 MAP2K6 phosphorylates PIP4K2B IEA Gallus gallus 30616 R-GGA-8878050 https://reactome.org/PathwayBrowser/#/R-GGA-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Gallus gallus 30616 R-GGA-8878054 https://reactome.org/PathwayBrowser/#/R-GGA-8878054 HIPK2 phosphorylates RUNX1 IEA Gallus gallus 30616 R-GGA-8931653 https://reactome.org/PathwayBrowser/#/R-GGA-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Gallus gallus 30616 R-GGA-8933446 https://reactome.org/PathwayBrowser/#/R-GGA-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Gallus gallus 30616 R-GGA-8934446 https://reactome.org/PathwayBrowser/#/R-GGA-8934446 Activated PKC phosphorylates SHC1 IEA Gallus gallus 30616 R-GGA-8937807 https://reactome.org/PathwayBrowser/#/R-GGA-8937807 SRC phosphorylates RUNX3 IEA Gallus gallus 30616 R-GGA-8939204 https://reactome.org/PathwayBrowser/#/R-GGA-8939204 ESTG binds ESR1:chaperone complex IEA Gallus gallus 30616 R-GGA-8939959 https://reactome.org/PathwayBrowser/#/R-GGA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Gallus gallus 30616 R-GGA-8940100 https://reactome.org/PathwayBrowser/#/R-GGA-8940100 CDK1 phosphorylates VCPIP1 IEA Gallus gallus 30616 R-GGA-8942575 https://reactome.org/PathwayBrowser/#/R-GGA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Gallus gallus 30616 R-GGA-8942607 https://reactome.org/PathwayBrowser/#/R-GGA-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Gallus gallus 30616 R-GGA-8942836 https://reactome.org/PathwayBrowser/#/R-GGA-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Gallus gallus 30616 R-GGA-8944454 https://reactome.org/PathwayBrowser/#/R-GGA-8944454 mTORC1 phosphorylates MAF1 IEA Gallus gallus 30616 R-GGA-8948143 https://reactome.org/PathwayBrowser/#/R-GGA-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Gallus gallus 30616 R-GGA-8948146 https://reactome.org/PathwayBrowser/#/R-GGA-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Gallus gallus 30616 R-GGA-8948757 https://reactome.org/PathwayBrowser/#/R-GGA-8948757 AKT phosphorylates MKRN1 IEA Gallus gallus 30616 R-GGA-8950269 https://reactome.org/PathwayBrowser/#/R-GGA-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Gallus gallus 30616 R-GGA-8950405 https://reactome.org/PathwayBrowser/#/R-GGA-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Gallus gallus 30616 R-GGA-8950423 https://reactome.org/PathwayBrowser/#/R-GGA-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Gallus gallus 30616 R-GGA-8950453 https://reactome.org/PathwayBrowser/#/R-GGA-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Gallus gallus 30616 R-GGA-8950757 https://reactome.org/PathwayBrowser/#/R-GGA-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Gallus gallus 30616 R-GGA-8951648 https://reactome.org/PathwayBrowser/#/R-GGA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Gallus gallus 30616 R-GGA-8951656 https://reactome.org/PathwayBrowser/#/R-GGA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Gallus gallus 30616 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus 30616 R-GGA-8954327 https://reactome.org/PathwayBrowser/#/R-GGA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Gallus gallus 30616 R-GGA-8955030 https://reactome.org/PathwayBrowser/#/R-GGA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Gallus gallus 30616 R-GGA-8955844 https://reactome.org/PathwayBrowser/#/R-GGA-8955844 RBKS phosphorylates ribose to R5P IEA Gallus gallus 30616 R-GGA-8956659 https://reactome.org/PathwayBrowser/#/R-GGA-8956659 ABL1 phosphorylates YAP1 IEA Gallus gallus 30616 R-GGA-8959719 https://reactome.org/PathwayBrowser/#/R-GGA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Gallus gallus 30616 R-GGA-8964242 https://reactome.org/PathwayBrowser/#/R-GGA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Gallus gallus 30616 R-GGA-8982163 https://reactome.org/PathwayBrowser/#/R-GGA-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Gallus gallus 30616 R-GGA-8983059 https://reactome.org/PathwayBrowser/#/R-GGA-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Gallus gallus 30616 R-GGA-8983063 https://reactome.org/PathwayBrowser/#/R-GGA-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Gallus gallus 30616 R-GGA-8983834 https://reactome.org/PathwayBrowser/#/R-GGA-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Gallus gallus 30616 R-GGA-8983835 https://reactome.org/PathwayBrowser/#/R-GGA-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Gallus gallus 30616 R-GGA-8983870 https://reactome.org/PathwayBrowser/#/R-GGA-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Gallus gallus 30616 R-GGA-8983872 https://reactome.org/PathwayBrowser/#/R-GGA-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Gallus gallus 30616 R-GGA-8984014 https://reactome.org/PathwayBrowser/#/R-GGA-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Gallus gallus 30616 R-GGA-8985914 https://reactome.org/PathwayBrowser/#/R-GGA-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Gallus gallus 30616 R-GGA-8985973 https://reactome.org/PathwayBrowser/#/R-GGA-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Gallus gallus 30616 R-GGA-8985988 https://reactome.org/PathwayBrowser/#/R-GGA-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Gallus gallus 30616 R-GGA-8986985 https://reactome.org/PathwayBrowser/#/R-GGA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Gallus gallus 30616 R-GGA-8986994 https://reactome.org/PathwayBrowser/#/R-GGA-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Gallus gallus 30616 R-GGA-8986995 https://reactome.org/PathwayBrowser/#/R-GGA-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Gallus gallus 30616 R-GGA-8987012 https://reactome.org/PathwayBrowser/#/R-GGA-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Gallus gallus 30616 R-GGA-8987040 https://reactome.org/PathwayBrowser/#/R-GGA-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Gallus gallus 30616 R-GGA-8987042 https://reactome.org/PathwayBrowser/#/R-GGA-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Gallus gallus 30616 R-GGA-8987070 https://reactome.org/PathwayBrowser/#/R-GGA-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Gallus gallus 30616 R-GGA-8987084 https://reactome.org/PathwayBrowser/#/R-GGA-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Gallus gallus 30616 R-GGA-8987096 https://reactome.org/PathwayBrowser/#/R-GGA-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Gallus gallus 30616 R-GGA-8987129 https://reactome.org/PathwayBrowser/#/R-GGA-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Gallus gallus 30616 R-GGA-8987141 https://reactome.org/PathwayBrowser/#/R-GGA-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Gallus gallus 30616 R-GGA-8987150 https://reactome.org/PathwayBrowser/#/R-GGA-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Gallus gallus 30616 R-GGA-8987179 https://reactome.org/PathwayBrowser/#/R-GGA-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Gallus gallus 30616 R-GGA-8987202 https://reactome.org/PathwayBrowser/#/R-GGA-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Gallus gallus 30616 R-GGA-8987255 https://reactome.org/PathwayBrowser/#/R-GGA-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Gallus gallus 30616 R-GGA-9006850 https://reactome.org/PathwayBrowser/#/R-GGA-9006850 IL21 receptor JAK phosphorylation IEA Gallus gallus 30616 R-GGA-9006870 https://reactome.org/PathwayBrowser/#/R-GGA-9006870 IL21 receptor STAT phosphorylation IEA Gallus gallus 30616 R-GGA-9008043 https://reactome.org/PathwayBrowser/#/R-GGA-9008043 MAPK8 phosphorylation IEA Gallus gallus 30616 R-GGA-9008684 https://reactome.org/PathwayBrowser/#/R-GGA-9008684 TBK1 phosphorylation IEA Gallus gallus 30616 R-GGA-9009072 https://reactome.org/PathwayBrowser/#/R-GGA-9009072 STAT3 phosphorylation IEA Gallus gallus 30616 R-GGA-9009936 https://reactome.org/PathwayBrowser/#/R-GGA-9009936 RNASEL cleaves cellular ssRNA IEA Gallus gallus 30616 R-GGA-9009950 https://reactome.org/PathwayBrowser/#/R-GGA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Gallus gallus 30616 R-GGA-9012319 https://reactome.org/PathwayBrowser/#/R-GGA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Gallus gallus 30616 R-GGA-9014741 https://reactome.org/PathwayBrowser/#/R-GGA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Gallus gallus 30616 R-GGA-9014766 https://reactome.org/PathwayBrowser/#/R-GGA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Gallus gallus 30616 R-GGA-9018572 https://reactome.org/PathwayBrowser/#/R-GGA-9018572 EGFR phosphorylates NOTCH3 IEA Gallus gallus 30616 R-GGA-9021357 https://reactome.org/PathwayBrowser/#/R-GGA-9021357 PRKCI phosphorylates ELF3 IEA Gallus gallus 30616 R-GGA-9021609 https://reactome.org/PathwayBrowser/#/R-GGA-9021609 ESR-associated SRC autophosphorylates IEA Gallus gallus 30616 R-GGA-9033499 https://reactome.org/PathwayBrowser/#/R-GGA-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Gallus gallus 30616 R-GGA-9034714 https://reactome.org/PathwayBrowser/#/R-GGA-9034714 NTRK3 dimers trans-autophosphorylate IEA Gallus gallus 30616 R-GGA-9038161 https://reactome.org/PathwayBrowser/#/R-GGA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Gallus gallus 30616 R-GGA-909552 https://reactome.org/PathwayBrowser/#/R-GGA-909552 Phosphorylation of STAT1 at Ser727 IEA Gallus gallus 30616 R-GGA-909718 https://reactome.org/PathwayBrowser/#/R-GGA-909718 Formation of p-STAT1 homodimer IEA Gallus gallus 30616 R-GGA-909729 https://reactome.org/PathwayBrowser/#/R-GGA-909729 Activation of JAK kinases IEA Gallus gallus 30616 R-GGA-909730 https://reactome.org/PathwayBrowser/#/R-GGA-909730 Phosphorylation of INFAR1 by TYK2 IEA Gallus gallus 30616 R-GGA-909732 https://reactome.org/PathwayBrowser/#/R-GGA-909732 Phosphorylation of STAT2 IEA Gallus gallus 30616 R-GGA-912527 https://reactome.org/PathwayBrowser/#/R-GGA-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Gallus gallus 30616 R-GGA-913996 https://reactome.org/PathwayBrowser/#/R-GGA-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Gallus gallus 30616 R-GGA-917693 https://reactome.org/PathwayBrowser/#/R-GGA-917693 ESCRT Disassembly IEA Gallus gallus 30616 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus 30616 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus 30616 R-GGA-936802 https://reactome.org/PathwayBrowser/#/R-GGA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Gallus gallus 30616 R-GGA-936883 https://reactome.org/PathwayBrowser/#/R-GGA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Gallus gallus 30616 R-GGA-936895 https://reactome.org/PathwayBrowser/#/R-GGA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Gallus gallus 30616 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 30616 R-GGA-936951 https://reactome.org/PathwayBrowser/#/R-GGA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Gallus gallus 30616 R-GGA-936991 https://reactome.org/PathwayBrowser/#/R-GGA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Gallus gallus 30616 R-GGA-937311 https://reactome.org/PathwayBrowser/#/R-GGA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Gallus gallus 30616 R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus 30616 R-GGA-947531 https://reactome.org/PathwayBrowser/#/R-GGA-947531 Molybdenum ion transfer onto molybdopterin IEA Gallus gallus 30616 R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus 30616 R-GGA-9603420 https://reactome.org/PathwayBrowser/#/R-GGA-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Gallus gallus 30616 R-GGA-9604328 https://reactome.org/PathwayBrowser/#/R-GGA-9604328 AKT1 phosphorylates NOTCH4 IEA Gallus gallus 30616 R-GGA-9606884 https://reactome.org/PathwayBrowser/#/R-GGA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Gallus gallus 30616 R-GGA-9607039 https://reactome.org/PathwayBrowser/#/R-GGA-9607039 LYN,SYK phosphorylate BTK TAS Gallus gallus 30616 R-GGA-9610153 https://reactome.org/PathwayBrowser/#/R-GGA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Gallus gallus 30616 R-GGA-9610156 https://reactome.org/PathwayBrowser/#/R-GGA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Gallus gallus 30616 R-GGA-9610163 https://reactome.org/PathwayBrowser/#/R-GGA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Gallus gallus 30616 R-GGA-9612501 https://reactome.org/PathwayBrowser/#/R-GGA-9612501 SGK phosphorylates CREB1 IEA Gallus gallus 30616 R-GGA-9612509 https://reactome.org/PathwayBrowser/#/R-GGA-9612509 SGK phosphorylates SRF IEA Gallus gallus 30616 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus 30616 R-GGA-9624526 https://reactome.org/PathwayBrowser/#/R-GGA-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Gallus gallus 30616 R-GGA-9624800 https://reactome.org/PathwayBrowser/#/R-GGA-9624800 CDK1 phosphorylates LBR IEA Gallus gallus 30616 R-GGA-9625487 https://reactome.org/PathwayBrowser/#/R-GGA-9625487 PTK2 autophosphorylates downstream of EGFR IEA Gallus gallus 30616 R-GGA-9626817 https://reactome.org/PathwayBrowser/#/R-GGA-9626817 PKC phosphorylates NCF1 IEA Gallus gallus 30616 R-GGA-9626832 https://reactome.org/PathwayBrowser/#/R-GGA-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Gallus gallus 30616 R-GGA-9626880 https://reactome.org/PathwayBrowser/#/R-GGA-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Gallus gallus 30616 R-GGA-9627056 https://reactome.org/PathwayBrowser/#/R-GGA-9627056 Procaspase 9 forms dimer IEA Gallus gallus 30616 R-GGA-9627089 https://reactome.org/PathwayBrowser/#/R-GGA-9627089 CASP9 is phosphorylated at T412 IEA Gallus gallus 30616 R-GGA-9632858 https://reactome.org/PathwayBrowser/#/R-GGA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Gallus gallus 30616 R-GGA-9632868 https://reactome.org/PathwayBrowser/#/R-GGA-9632868 CDKN1B is phosphorylated in response to estrogen IEA Gallus gallus 30616 R-GGA-9634702 https://reactome.org/PathwayBrowser/#/R-GGA-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Gallus gallus 30616 R-GGA-9645442 https://reactome.org/PathwayBrowser/#/R-GGA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Gallus gallus 30616 R-GGA-9645535 https://reactome.org/PathwayBrowser/#/R-GGA-9645535 ALPK1 phosphorylates TIFA IEA Gallus gallus 30616 R-GGA-9648089 https://reactome.org/PathwayBrowser/#/R-GGA-9648089 NEK6 and NEK7 phosphorylate EML4 IEA Gallus gallus 30616 R-GGA-964958 https://reactome.org/PathwayBrowser/#/R-GGA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Gallus gallus 30616 R-GGA-964962 https://reactome.org/PathwayBrowser/#/R-GGA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Gallus gallus 30616 R-GGA-964970 https://reactome.org/PathwayBrowser/#/R-GGA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Gallus gallus 30616 R-GGA-9653503 https://reactome.org/PathwayBrowser/#/R-GGA-9653503 KRAS4B is phosphorylated on serine 181 IEA Gallus gallus 30616 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 30616 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 30616 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus 30616 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 30616 R-GGA-9699579 https://reactome.org/PathwayBrowser/#/R-GGA-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Gallus gallus 30616 R-GGA-9700168 https://reactome.org/PathwayBrowser/#/R-GGA-9700168 Active ALK phosphorylates IRS1 IEA Gallus gallus 30616 R-GGA-9700171 https://reactome.org/PathwayBrowser/#/R-GGA-9700171 Active ALK phosphorylates PLCG1 IEA Gallus gallus 30616 R-GGA-9700175 https://reactome.org/PathwayBrowser/#/R-GGA-9700175 Active ALK phosphorylates SHC1 IEA Gallus gallus 30616 R-GGA-9705925 https://reactome.org/PathwayBrowser/#/R-GGA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Gallus gallus 30616 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 30616 R-GGA-9706390 https://reactome.org/PathwayBrowser/#/R-GGA-9706390 RHOBTB3 binds interacting proteins at trans-Golgi network IEA Gallus gallus 30616 R-GGA-9706393 https://reactome.org/PathwayBrowser/#/R-GGA-9706393 RHOBTB3 binds ATP IEA Gallus gallus 30616 R-GGA-9706399 https://reactome.org/PathwayBrowser/#/R-GGA-9706399 RHOBTB3 hydrolyzes ATP IEA Gallus gallus 30616 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus 30616 R-GGA-9709547 https://reactome.org/PathwayBrowser/#/R-GGA-9709547 ESTG binds ESR2:chaperone complex IEA Gallus gallus 30616 R-GGA-9716913 https://reactome.org/PathwayBrowser/#/R-GGA-9716913 ESR1 binds ESR1 antagonists IEA Gallus gallus 30616 R-GGA-9716947 https://reactome.org/PathwayBrowser/#/R-GGA-9716947 ESR1 binds ESR1 agonists IEA Gallus gallus 30616 R-GGA-9725855 https://reactome.org/PathwayBrowser/#/R-GGA-9725855 NR3C2 binds NR3C2 antagonists IEA Gallus gallus 30616 R-GGA-9725885 https://reactome.org/PathwayBrowser/#/R-GGA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Gallus gallus 30616 R-GGA-9726509 https://reactome.org/PathwayBrowser/#/R-GGA-9726509 NR3C2 binds fludrocortisone IEA Gallus gallus 30616 R-GGA-9726580 https://reactome.org/PathwayBrowser/#/R-GGA-9726580 PGR binds PGR agonists IEA Gallus gallus 30616 R-GGA-9726621 https://reactome.org/PathwayBrowser/#/R-GGA-9726621 PGR binds PGR antagonists IEA Gallus gallus 30616 R-GGA-9731111 https://reactome.org/PathwayBrowser/#/R-GGA-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Gallus gallus 30616 R-GGA-9732738 https://reactome.org/PathwayBrowser/#/R-GGA-9732738 JAK1-mediated phosphorylation of RAF1 IEA Gallus gallus 30616 R-GGA-9732753 https://reactome.org/PathwayBrowser/#/R-GGA-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Gallus gallus 30616 R-GGA-9734535 https://reactome.org/PathwayBrowser/#/R-GGA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Gallus gallus 30616 R-GGA-9734547 https://reactome.org/PathwayBrowser/#/R-GGA-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Gallus gallus 30616 R-GGA-9734687 https://reactome.org/PathwayBrowser/#/R-GGA-9734687 ORC6 is phosphorylated on T195 IEA Gallus gallus 30616 R-GGA-9748949 https://reactome.org/PathwayBrowser/#/R-GGA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Gallus gallus 30616 R-GGA-9748957 https://reactome.org/PathwayBrowser/#/R-GGA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Gallus gallus 30616 R-GGA-9748963 https://reactome.org/PathwayBrowser/#/R-GGA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Gallus gallus 30616 R-GGA-9748969 https://reactome.org/PathwayBrowser/#/R-GGA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Gallus gallus 30616 R-GGA-9748999 https://reactome.org/PathwayBrowser/#/R-GGA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Gallus gallus 30616 R-GGA-9749971 https://reactome.org/PathwayBrowser/#/R-GGA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Gallus gallus 30616 R-GGA-9750546 https://reactome.org/PathwayBrowser/#/R-GGA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 30616 R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 30616 R-GGA-9750656 https://reactome.org/PathwayBrowser/#/R-GGA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Gallus gallus 30616 R-GGA-975103 https://reactome.org/PathwayBrowser/#/R-GGA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Gallus gallus 30616 R-GGA-9753278 https://reactome.org/PathwayBrowser/#/R-GGA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 30616 R-GGA-9753283 https://reactome.org/PathwayBrowser/#/R-GGA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 30616 R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 30616 R-GGA-9754974 https://reactome.org/PathwayBrowser/#/R-GGA-9754974 ADK phosphorylates RBV IEA Gallus gallus 30616 R-GGA-9755013 https://reactome.org/PathwayBrowser/#/R-GGA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Gallus gallus 30616 R-GGA-9759206 https://reactome.org/PathwayBrowser/#/R-GGA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Gallus gallus 30616 R-GGA-9759454 https://reactome.org/PathwayBrowser/#/R-GGA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Gallus gallus 30616 R-GGA-9759461 https://reactome.org/PathwayBrowser/#/R-GGA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Gallus gallus 30616 R-GGA-9760094 https://reactome.org/PathwayBrowser/#/R-GGA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Gallus gallus 30616 R-GGA-9762094 https://reactome.org/PathwayBrowser/#/R-GGA-9762094 GSK3B phosphorylates p-NFE2L2 IEA Gallus gallus 30616 R-GGA-977239 https://reactome.org/PathwayBrowser/#/R-GGA-977239 Activated IRAK4 bound to activated TLR : MyD88 complex phosphorylates IRAK2 IEA Gallus gallus 30616 R-GGA-977250 https://reactome.org/PathwayBrowser/#/R-GGA-977250 Autophosphorylation of IRAK4 bound to activated TLR5 or 15 IEA Gallus gallus 30616 R-GGA-9796053 https://reactome.org/PathwayBrowser/#/R-GGA-9796053 PRKCI phosphorylates NFE2L2 IEA Gallus gallus 30616 R-GGA-9796067 https://reactome.org/PathwayBrowser/#/R-GGA-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Gallus gallus 30616 R-GGA-9815501 https://reactome.org/PathwayBrowser/#/R-GGA-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 IEA Gallus gallus 30616 R-GGA-9817397 https://reactome.org/PathwayBrowser/#/R-GGA-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Gallus gallus 30616 R-GGA-9819106 https://reactome.org/PathwayBrowser/#/R-GGA-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Gallus gallus 30616 R-GGA-9823906 https://reactome.org/PathwayBrowser/#/R-GGA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Gallus gallus 30616 R-GGA-9824882 https://reactome.org/PathwayBrowser/#/R-GGA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Gallus gallus 30616 R-GGA-9824977 https://reactome.org/PathwayBrowser/#/R-GGA-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Gallus gallus 30616 R-GGA-9824994 https://reactome.org/PathwayBrowser/#/R-GGA-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Gallus gallus 30616 R-GGA-9824995 https://reactome.org/PathwayBrowser/#/R-GGA-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Gallus gallus 30616 R-GGA-9824999 https://reactome.org/PathwayBrowser/#/R-GGA-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Gallus gallus 30616 R-GGA-9825759 https://reactome.org/PathwayBrowser/#/R-GGA-9825759 MAPK-dependent phosphorylation of KARS IEA Gallus gallus 30616 R-GGA-982807 https://reactome.org/PathwayBrowser/#/R-GGA-982807 JAK2 phosphorylation of GHR IEA Gallus gallus 30616 R-GGA-982810 https://reactome.org/PathwayBrowser/#/R-GGA-982810 JAK2 phosphorylation IEA Gallus gallus 30616 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus 30616 R-GGA-983153 https://reactome.org/PathwayBrowser/#/R-GGA-983153 E1 mediated ubiquitin activation IEA Gallus gallus 30616 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus 30616 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus 30616 R-GGA-9836184 https://reactome.org/PathwayBrowser/#/R-GGA-9836184 p-PKR dimer phosphorylates CDK1 IEA Gallus gallus 30616 R-GGA-9836322 https://reactome.org/PathwayBrowser/#/R-GGA-9836322 p-PKR dimer phosphorylates MKK6 IEA Gallus gallus 30616 R-GGA-9836383 https://reactome.org/PathwayBrowser/#/R-GGA-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Gallus gallus 30616 R-GGA-9836435 https://reactome.org/PathwayBrowser/#/R-GGA-9836435 p-PKR dimer phosphorylates SNCA IEA Gallus gallus 30616 R-GGA-9836515 https://reactome.org/PathwayBrowser/#/R-GGA-9836515 p-PKR dimer phosphorylates PTPN2 IEA Gallus gallus 30616 R-GGA-9836617 https://reactome.org/PathwayBrowser/#/R-GGA-9836617 p-PKR dimer phosphorylates SPHK1 IEA Gallus gallus 30616 R-GGA-983703 https://reactome.org/PathwayBrowser/#/R-GGA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Gallus gallus 30616 R-GGA-983707 https://reactome.org/PathwayBrowser/#/R-GGA-983707 SYK autophosphorylates at the activated BCR IEA Gallus gallus 30616 R-GGA-9837337 https://reactome.org/PathwayBrowser/#/R-GGA-9837337 DCAKD phosphorylates DP-CoA IEA Gallus gallus 30616 R-GGA-9838004 https://reactome.org/PathwayBrowser/#/R-GGA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Gallus gallus 30616 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus 30616 R-GGA-9839059 https://reactome.org/PathwayBrowser/#/R-GGA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Gallus gallus 30616 R-GGA-9839105 https://reactome.org/PathwayBrowser/#/R-GGA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Gallus gallus 30616 R-GGA-9839113 https://reactome.org/PathwayBrowser/#/R-GGA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Gallus gallus 30616 R-GGA-9840564 https://reactome.org/PathwayBrowser/#/R-GGA-9840564 OMA1 hydrolyzes YME1L1 IEA Gallus gallus 30616 R-GGA-9842648 https://reactome.org/PathwayBrowser/#/R-GGA-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 IEA Gallus gallus 30616 R-GGA-9842651 https://reactome.org/PathwayBrowser/#/R-GGA-9842651 Active LTK receptor phosphorylates SHC1 IEA Gallus gallus 30616 R-GGA-9842666 https://reactome.org/PathwayBrowser/#/R-GGA-9842666 Active LTK phosphorylates IRS1 IEA Gallus gallus 30616 R-GGA-9843721 https://reactome.org/PathwayBrowser/#/R-GGA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Gallus gallus 30616 R-GGA-9851972 https://reactome.org/PathwayBrowser/#/R-GGA-9851972 PLK1 phosphorylates FIRRM at S43 IEA Gallus gallus 30616 R-GGA-9853369 https://reactome.org/PathwayBrowser/#/R-GGA-9853369 PLK1 phosphorylates FIRMM at S744 IEA Gallus gallus 30616 R-GGA-9861642 https://reactome.org/PathwayBrowser/#/R-GGA-9861642 NEK1 phosphorylates ME1 IEA Gallus gallus 30616 R-GGA-994000 https://reactome.org/PathwayBrowser/#/R-GGA-994000 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation IEA Gallus gallus 30616 R-GGA-994137 https://reactome.org/PathwayBrowser/#/R-GGA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Gallus gallus 30616 R-GGA-994140 https://reactome.org/PathwayBrowser/#/R-GGA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Gallus gallus 30616 R-HSA-109624 https://reactome.org/PathwayBrowser/#/R-HSA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) TAS Homo sapiens 30616 R-HSA-109671 https://reactome.org/PathwayBrowser/#/R-HSA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) TAS Homo sapiens 30616 R-HSA-109699 https://reactome.org/PathwayBrowser/#/R-HSA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-109702 https://reactome.org/PathwayBrowser/#/R-HSA-109702 PDPK1 phosphorylates AKT2 TAS Homo sapiens 30616 R-HSA-109759 https://reactome.org/PathwayBrowser/#/R-HSA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] TAS Homo sapiens 30616 R-HSA-109822 https://reactome.org/PathwayBrowser/#/R-HSA-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 TAS Homo sapiens 30616 R-HSA-109823 https://reactome.org/PathwayBrowser/#/R-HSA-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 TAS Homo sapiens 30616 R-HSA-109860 https://reactome.org/PathwayBrowser/#/R-HSA-109860 MAP2K1 phosphorylates MAPK3 TAS Homo sapiens 30616 R-HSA-109862 https://reactome.org/PathwayBrowser/#/R-HSA-109862 MAP2K2 phosphorylates MAPK1 TAS Homo sapiens 30616 R-HSA-109903 https://reactome.org/PathwayBrowser/#/R-HSA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] TAS Homo sapiens 30616 R-HSA-110133 https://reactome.org/PathwayBrowser/#/R-HSA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) TAS Homo sapiens 30616 R-HSA-110137 https://reactome.org/PathwayBrowser/#/R-HSA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP TAS Homo sapiens 30616 R-HSA-110138 https://reactome.org/PathwayBrowser/#/R-HSA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 30616 R-HSA-110141 https://reactome.org/PathwayBrowser/#/R-HSA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) TAS Homo sapiens 30616 R-HSA-110144 https://reactome.org/PathwayBrowser/#/R-HSA-110144 ADP + ADP <=> AMP + ATP [AK2] TAS Homo sapiens 30616 R-HSA-110145 https://reactome.org/PathwayBrowser/#/R-HSA-110145 AMP + ATP <=> ADP + ADP [AK2] TAS Homo sapiens 30616 R-HSA-1112510 https://reactome.org/PathwayBrowser/#/R-HSA-1112510 IL6ST is tyrosine phosphorylated TAS Homo sapiens 30616 R-HSA-1112514 https://reactome.org/PathwayBrowser/#/R-HSA-1112514 JAK activation TAS Homo sapiens 30616 R-HSA-1112602 https://reactome.org/PathwayBrowser/#/R-HSA-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor TAS Homo sapiens 30616 R-HSA-1112703 https://reactome.org/PathwayBrowser/#/R-HSA-1112703 PTPN11 is phosphorylated TAS Homo sapiens 30616 R-HSA-1112727 https://reactome.org/PathwayBrowser/#/R-HSA-1112727 Serine phosphorylation of STATs TAS Homo sapiens 30616 R-HSA-111742 https://reactome.org/PathwayBrowser/#/R-HSA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 30616 R-HSA-111751 https://reactome.org/PathwayBrowser/#/R-HSA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 30616 R-HSA-111804 https://reactome.org/PathwayBrowser/#/R-HSA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 30616 R-HSA-111898 https://reactome.org/PathwayBrowser/#/R-HSA-111898 Phosphorylation of cPLA2 by ERK-2 TAS Homo sapiens 30616 R-HSA-111912 https://reactome.org/PathwayBrowser/#/R-HSA-111912 CaMK4 phosphorylates CREB1 IEA Homo sapiens 30616 R-HSA-111915 https://reactome.org/PathwayBrowser/#/R-HSA-111915 CAMK4 autophosphorylates TAS Homo sapiens 30616 R-HSA-111919 https://reactome.org/PathwayBrowser/#/R-HSA-111919 PKA phosphorylates CREB1 IEA Homo sapiens 30616 R-HSA-111930 https://reactome.org/PathwayBrowser/#/R-HSA-111930 Adenylate cyclase produces cAMP TAS Homo sapiens 30616 R-HSA-111970 https://reactome.org/PathwayBrowser/#/R-HSA-111970 PKC phosphorylates GRK2 TAS Homo sapiens 30616 R-HSA-112282 https://reactome.org/PathwayBrowser/#/R-HSA-112282 CAMK4 enters the nucleus IEA Homo sapiens 30616 R-HSA-112333 https://reactome.org/PathwayBrowser/#/R-HSA-112333 SRC autophosphorylation is positively regulated by InlA-bound CDH1 TAS Homo sapiens 30616 R-HSA-112342 https://reactome.org/PathwayBrowser/#/R-HSA-112342 Inactivation of MAP2K1 by CDK1 TAS Homo sapiens 30616 R-HSA-112381 https://reactome.org/PathwayBrowser/#/R-HSA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex TAS Homo sapiens 30616 R-HSA-114252 https://reactome.org/PathwayBrowser/#/R-HSA-114252 Cleavage of Procaspase-3 by the apoptosome TAS Homo sapiens 30616 R-HSA-114254 https://reactome.org/PathwayBrowser/#/R-HSA-114254 CYCS binds to APAF1 TAS Homo sapiens 30616 R-HSA-114256 https://reactome.org/PathwayBrowser/#/R-HSA-114256 CYCS:APAF1 binds procaspase-9 TAS Homo sapiens 30616 R-HSA-114261 https://reactome.org/PathwayBrowser/#/R-HSA-114261 Cleavage of Procaspase-7 by the apoptosome TAS Homo sapiens 30616 R-HSA-114600 https://reactome.org/PathwayBrowser/#/R-HSA-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma TAS Homo sapiens 30616 R-HSA-114683 https://reactome.org/PathwayBrowser/#/R-HSA-114683 Phosphorylation of Platelet Sec-1 TAS Homo sapiens 30616 R-HSA-114684 https://reactome.org/PathwayBrowser/#/R-HSA-114684 Phosphorylation of Syntaxin-4 TAS Homo sapiens 30616 R-HSA-1168374 https://reactome.org/PathwayBrowser/#/R-HSA-1168374 RasGRP1 and RasGRP3 binds diacylglycerol and is phosphorylated IEA Homo sapiens 30616 R-HSA-1168394 https://reactome.org/PathwayBrowser/#/R-HSA-1168394 STAT5 tyrosine phosphorylation IEA Homo sapiens 30616 R-HSA-1168423 https://reactome.org/PathwayBrowser/#/R-HSA-1168423 JAK2 phosphorylation of IRS-1/2 IEA Homo sapiens 30616 R-HSA-1168459 https://reactome.org/PathwayBrowser/#/R-HSA-1168459 Lyn activates ERK TAS Homo sapiens 30616 R-HSA-1168635 https://reactome.org/PathwayBrowser/#/R-HSA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 TAS Homo sapiens 30616 R-HSA-1168638 https://reactome.org/PathwayBrowser/#/R-HSA-1168638 Activated IKK phosphorylates I-kappaB TAS Homo sapiens 30616 R-HSA-1168641 https://reactome.org/PathwayBrowser/#/R-HSA-1168641 TAK1 associated with the CBM complex phosphorylates IKKbeta IEA Homo sapiens 30616 R-HSA-1168767 https://reactome.org/PathwayBrowser/#/R-HSA-1168767 JAK2 phosphorylates STAT1/STAT3 IEA Homo sapiens 30616 R-HSA-1169394 https://reactome.org/PathwayBrowser/#/R-HSA-1169394 ISGylation of IRF3 TAS Homo sapiens 30616 R-HSA-1169395 https://reactome.org/PathwayBrowser/#/R-HSA-1169395 ISGylation of viral protein NS1 TAS Homo sapiens 30616 R-HSA-1169397 https://reactome.org/PathwayBrowser/#/R-HSA-1169397 Activation of ISG15 by UBA7 E1 ligase TAS Homo sapiens 30616 R-HSA-1169398 https://reactome.org/PathwayBrowser/#/R-HSA-1169398 ISGylation of host protein filamin B TAS Homo sapiens 30616 R-HSA-1169402 https://reactome.org/PathwayBrowser/#/R-HSA-1169402 ISGylation of E2 conjugating enzymes TAS Homo sapiens 30616 R-HSA-1169405 https://reactome.org/PathwayBrowser/#/R-HSA-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) TAS Homo sapiens 30616 R-HSA-1169406 https://reactome.org/PathwayBrowser/#/R-HSA-1169406 ISGylation of host proteins TAS Homo sapiens 30616 R-HSA-1169421 https://reactome.org/PathwayBrowser/#/R-HSA-1169421 Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers TAS Homo sapiens 30616 R-HSA-1181149 https://reactome.org/PathwayBrowser/#/R-HSA-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin TAS Homo sapiens 30616 R-HSA-1181156 https://reactome.org/PathwayBrowser/#/R-HSA-1181156 Type II Activin Receptor (ActRII/ACVR2) phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in response to NODAL IEA Homo sapiens 30616 R-HSA-1181355 https://reactome.org/PathwayBrowser/#/R-HSA-1181355 Phosphorylation of R-SMAD2/3 by NODAL receptor IEA Homo sapiens 30616 R-HSA-1225894 https://reactome.org/PathwayBrowser/#/R-HSA-1225894 Type II Activin Receptor (ActRIIB/ACVR2B) phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in response to NODAL IEA Homo sapiens 30616 R-HSA-1225952 https://reactome.org/PathwayBrowser/#/R-HSA-1225952 Phosphorylation of SHC1 by ligand-responsive p-6Y-EGFR mutants TAS Homo sapiens 30616 R-HSA-1225960 https://reactome.org/PathwayBrowser/#/R-HSA-1225960 Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants TAS Homo sapiens 30616 R-HSA-1226014 https://reactome.org/PathwayBrowser/#/R-HSA-1226014 Conversion of PIP2 to PIP3 by PI3K bound to ligand-responsive p-6Y-EGFR mutants TAS Homo sapiens 30616 R-HSA-1226094 https://reactome.org/PathwayBrowser/#/R-HSA-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex TAS Homo sapiens 30616 R-HSA-1226095 https://reactome.org/PathwayBrowser/#/R-HSA-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex TAS Homo sapiens 30616 R-HSA-1236949 https://reactome.org/PathwayBrowser/#/R-HSA-1236949 Translocation of antigenic peptides back to phagosomes via TAP IEA Homo sapiens 30616 R-HSA-1247844 https://reactome.org/PathwayBrowser/#/R-HSA-1247844 Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants TAS Homo sapiens 30616 R-HSA-1247935 https://reactome.org/PathwayBrowser/#/R-HSA-1247935 OPLAH hydrolyses OPRO to L-Glu TAS Homo sapiens 30616 R-HSA-1247960 https://reactome.org/PathwayBrowser/#/R-HSA-1247960 Activation of p38 MAPK TAS Homo sapiens 30616 R-HSA-1248655 https://reactome.org/PathwayBrowser/#/R-HSA-1248655 Trans-autophosphorylation of EGFRvIII mutant dimers TAS Homo sapiens 30616 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 30616 R-HSA-1250195 https://reactome.org/PathwayBrowser/#/R-HSA-1250195 SHC1 phosphorylation by ERBB2 heterodimers TAS Homo sapiens 30616 R-HSA-1250315 https://reactome.org/PathwayBrowser/#/R-HSA-1250315 Trans-autophosphorylation of ERBB4 homodimers TAS Homo sapiens 30616 R-HSA-1250348 https://reactome.org/PathwayBrowser/#/R-HSA-1250348 Phosphorylation of SHC1 by ERBB4 homodimers TAS Homo sapiens 30616 R-HSA-1250370 https://reactome.org/PathwayBrowser/#/R-HSA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers TAS Homo sapiens 30616 R-HSA-1250462 https://reactome.org/PathwayBrowser/#/R-HSA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 TAS Homo sapiens 30616 R-HSA-1251922 https://reactome.org/PathwayBrowser/#/R-HSA-1251922 PLCG1 phosphorylation by p-EGFR:p-ERBB2 IEA Homo sapiens 30616 R-HSA-1295519 https://reactome.org/PathwayBrowser/#/R-HSA-1295519 IL7R is phosphorylated on Y499 IEA Homo sapiens 30616 R-HSA-1295540 https://reactome.org/PathwayBrowser/#/R-HSA-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 TAS Homo sapiens 30616 R-HSA-1295609 https://reactome.org/PathwayBrowser/#/R-HSA-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 TAS Homo sapiens 30616 R-HSA-1296024 https://reactome.org/PathwayBrowser/#/R-HSA-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells TAS Homo sapiens 30616 R-HSA-1299475 https://reactome.org/PathwayBrowser/#/R-HSA-1299475 TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix IEA Homo sapiens 30616 R-HSA-1306957 https://reactome.org/PathwayBrowser/#/R-HSA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR TAS Homo sapiens 30616 R-HSA-1306979 https://reactome.org/PathwayBrowser/#/R-HSA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 TAS Homo sapiens 30616 R-HSA-1307963 https://reactome.org/PathwayBrowser/#/R-HSA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 TAS Homo sapiens 30616 R-HSA-1358791 https://reactome.org/PathwayBrowser/#/R-HSA-1358791 Phosphorylation of USP8 by P-AKT TAS Homo sapiens 30616 R-HSA-1362270 https://reactome.org/PathwayBrowser/#/R-HSA-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A TAS Homo sapiens 30616 R-HSA-1364043 https://reactome.org/PathwayBrowser/#/R-HSA-1364043 Tyrosine phosphorylation of PRLR IEA Homo sapiens 30616 R-HSA-1369028 https://reactome.org/PathwayBrowser/#/R-HSA-1369028 ABCAs mediate lipid efflux TAS Homo sapiens 30616 R-HSA-1369052 https://reactome.org/PathwayBrowser/#/R-HSA-1369052 ABCAs mediate lipid influx TAS Homo sapiens 30616 R-HSA-1369065 https://reactome.org/PathwayBrowser/#/R-HSA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix TAS Homo sapiens 30616 R-HSA-1369115 https://reactome.org/PathwayBrowser/#/R-HSA-1369115 SHP2 is phosphorylated IEA Homo sapiens 30616 R-HSA-1370505 https://reactome.org/PathwayBrowser/#/R-HSA-1370505 PRLR is phosphorylated at Ser-349 TAS Homo sapiens 30616 R-HSA-139855 https://reactome.org/PathwayBrowser/#/R-HSA-139855 P2X1-mediated entry of Ca++ from plasma TAS Homo sapiens 30616 R-HSA-139908 https://reactome.org/PathwayBrowser/#/R-HSA-139908 Phosphorylation of DLC2 by MAPK8 TAS Homo sapiens 30616 R-HSA-139918 https://reactome.org/PathwayBrowser/#/R-HSA-139918 Phosphorylation of BIM by JNK TAS Homo sapiens 30616 R-HSA-1433418 https://reactome.org/PathwayBrowser/#/R-HSA-1433418 Phosphorylation of JAK2 TAS Homo sapiens 30616 R-HSA-1433454 https://reactome.org/PathwayBrowser/#/R-HSA-1433454 Phosphorylation of GAB2 by SFKs TAS Homo sapiens 30616 R-HSA-1433488 https://reactome.org/PathwayBrowser/#/R-HSA-1433488 Phosphorylation of SHP2 by SFKs TAS Homo sapiens 30616 R-HSA-1433506 https://reactome.org/PathwayBrowser/#/R-HSA-1433506 Phosphorylation of APS TAS Homo sapiens 30616 R-HSA-1433508 https://reactome.org/PathwayBrowser/#/R-HSA-1433508 PKC alpha interacts with and phosphorylates KIT TAS Homo sapiens 30616 R-HSA-1433514 https://reactome.org/PathwayBrowser/#/R-HSA-1433514 Synthesis of PIP3 from PIP2 by PI3K TAS Homo sapiens 30616 R-HSA-1433542 https://reactome.org/PathwayBrowser/#/R-HSA-1433542 Phosphorylation and activation of VAV1 TAS Homo sapiens 30616 R-HSA-1445144 https://reactome.org/PathwayBrowser/#/R-HSA-1445144 p-AKT1,p-AKT2 phosphorylates AS160 (TBC1D4) IEA Homo sapiens 30616 R-HSA-1449574 https://reactome.org/PathwayBrowser/#/R-HSA-1449574 SLC2A4 (GLUT4) vesicle fuses with the plasma membrane IEA Homo sapiens 30616 R-HSA-1449597 https://reactome.org/PathwayBrowser/#/R-HSA-1449597 p-AKT2 phosphorylates Myosin 5A IEA Homo sapiens 30616 R-HSA-1454699 https://reactome.org/PathwayBrowser/#/R-HSA-1454699 AMPK-alpha2 phosphorylates TBC1D1 IEA Homo sapiens 30616 R-HSA-1454916 https://reactome.org/PathwayBrowser/#/R-HSA-1454916 The ABCC family mediates organic anion transport TAS Homo sapiens 30616 R-HSA-1454928 https://reactome.org/PathwayBrowser/#/R-HSA-1454928 ABCG4 may mediate cholesterol efflux TAS Homo sapiens 30616 R-HSA-1458463 https://reactome.org/PathwayBrowser/#/R-HSA-1458463 p-AKT2 phosphorylates RGC2 IEA Homo sapiens 30616 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-1467466 https://reactome.org/PathwayBrowser/#/R-HSA-1467466 ABCA4 mediates atRAL transport TAS Homo sapiens 30616 R-HSA-1470009 https://reactome.org/PathwayBrowser/#/R-HSA-1470009 Phosphorylation of STATs TAS Homo sapiens 30616 R-HSA-1472121 https://reactome.org/PathwayBrowser/#/R-HSA-1472121 Phosphorylation of p-KIT on Y900 by Src kinases TAS Homo sapiens 30616 R-HSA-1475422 https://reactome.org/PathwayBrowser/#/R-HSA-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II TAS Homo sapiens 30616 R-HSA-1483004 https://reactome.org/PathwayBrowser/#/R-HSA-1483004 Cho is phosphorylated to PCho by CHK dimer TAS Homo sapiens 30616 R-HSA-1483222 https://reactome.org/PathwayBrowser/#/R-HSA-1483222 ETA is phosphorylated to PETA by CHK/ETNK TAS Homo sapiens 30616 R-HSA-1497853 https://reactome.org/PathwayBrowser/#/R-HSA-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II TAS Homo sapiens 30616 R-HSA-1524186 https://reactome.org/PathwayBrowser/#/R-HSA-1524186 Phosphorylation of PLCgamma by PDGFR TAS Homo sapiens 30616 R-HSA-1549526 https://reactome.org/PathwayBrowser/#/R-HSA-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor TAS Homo sapiens 30616 R-HSA-156673 https://reactome.org/PathwayBrowser/#/R-HSA-156673 Regulation of KIF23 (MKLP1) by phosphorylation TAS Homo sapiens 30616 R-HSA-156678 https://reactome.org/PathwayBrowser/#/R-HSA-156678 Activation of Cdc25C TAS Homo sapiens 30616 R-HSA-156682 https://reactome.org/PathwayBrowser/#/R-HSA-156682 PLK1 phosphorylates NUDC TAS Homo sapiens 30616 R-HSA-156699 https://reactome.org/PathwayBrowser/#/R-HSA-156699 Inactivation of Wee1 kinase TAS Homo sapiens 30616 R-HSA-156723 https://reactome.org/PathwayBrowser/#/R-HSA-156723 Regulation of KIF20A (MKL2) by phosphorylation TAS Homo sapiens 30616 R-HSA-156832 https://reactome.org/PathwayBrowser/#/R-HSA-156832 INF-gamma induced phosphorylation of L13a TAS Homo sapiens 30616 R-HSA-159101 https://reactome.org/PathwayBrowser/#/R-HSA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) TAS Homo sapiens 30616 R-HSA-1592233 https://reactome.org/PathwayBrowser/#/R-HSA-1592233 p38 MAPK phosphorylates PPARGC1A IEA Homo sapiens 30616 R-HSA-1592244 https://reactome.org/PathwayBrowser/#/R-HSA-1592244 AMPK phosphorylates PPARGC1A IEA Homo sapiens 30616 R-HSA-159425 https://reactome.org/PathwayBrowser/#/R-HSA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 30616 R-HSA-159443 https://reactome.org/PathwayBrowser/#/R-HSA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-159567 https://reactome.org/PathwayBrowser/#/R-HSA-159567 ACSM2B-like proteins transform ST to ST-CoA TAS Homo sapiens 30616 R-HSA-1606324 https://reactome.org/PathwayBrowser/#/R-HSA-1606324 Recruitment TBK1 to dsDNA:ZBP1 followed by its activation IEA Homo sapiens 30616 R-HSA-1606327 https://reactome.org/PathwayBrowser/#/R-HSA-1606327 Phosphorylation and release of IRF3 TAS Homo sapiens 30616 R-HSA-162363 https://reactome.org/PathwayBrowser/#/R-HSA-162363 p-T309,S474-AKT2:PIP3 phosphorylates PDE3B IEA Homo sapiens 30616 R-HSA-162657 https://reactome.org/PathwayBrowser/#/R-HSA-162657 Inactivation of Myt1 kinase TAS Homo sapiens 30616 R-HSA-163010 https://reactome.org/PathwayBrowser/#/R-HSA-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 TAS Homo sapiens 30616 R-HSA-163120 https://reactome.org/PathwayBrowser/#/R-HSA-163120 Disassociation of Telomerase RNP and the Chromosome End TAS Homo sapiens 30616 R-HSA-163215 https://reactome.org/PathwayBrowser/#/R-HSA-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane TAS Homo sapiens 30616 R-HSA-1632857 https://reactome.org/PathwayBrowser/#/R-HSA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex TAS Homo sapiens 30616 R-HSA-163416 https://reactome.org/PathwayBrowser/#/R-HSA-163416 hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP IEA Homo sapiens 30616 R-HSA-163418 https://reactome.org/PathwayBrowser/#/R-HSA-163418 perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP IEA Homo sapiens 30616 R-HSA-163672 https://reactome.org/PathwayBrowser/#/R-HSA-163672 Phosphorylation of ChREBP at Thr(653) by PKA IEA Homo sapiens 30616 R-HSA-163676 https://reactome.org/PathwayBrowser/#/R-HSA-163676 Phosphorylation of pChREBP (Thr 653) at Ser(196) by PKA IEA Homo sapiens 30616 R-HSA-163691 https://reactome.org/PathwayBrowser/#/R-HSA-163691 Phosphorylation of ChREBP at Serine 556 by AMPK IEA Homo sapiens 30616 R-HSA-163773 https://reactome.org/PathwayBrowser/#/R-HSA-163773 Phosphorylation of PF2K-Pase by PKA catalytic subunit IEA Homo sapiens 30616 R-HSA-1638803 https://reactome.org/PathwayBrowser/#/R-HSA-1638803 Phosphorylation of cohesin by PLK1 at centromeres TAS Homo sapiens 30616 R-HSA-1638845 https://reactome.org/PathwayBrowser/#/R-HSA-1638845 CERK phosphorylates CERA to form C1P TAS Homo sapiens 30616 R-HSA-164151 https://reactome.org/PathwayBrowser/#/R-HSA-164151 LKB1 phosphorylates the alpha subunit of AMPK heterotrimer IEA Homo sapiens 30616 R-HSA-164377 https://reactome.org/PathwayBrowser/#/R-HSA-164377 Activated Adenylate cyclase catalyses cAMP synthesis TAS Homo sapiens 30616 R-HSA-164832 https://reactome.org/PathwayBrowser/#/R-HSA-164832 ATPase synthesizes ATP TAS Homo sapiens 30616 R-HSA-164834 https://reactome.org/PathwayBrowser/#/R-HSA-164834 Enzyme-bound ATP is released TAS Homo sapiens 30616 R-HSA-165162 https://reactome.org/PathwayBrowser/#/R-HSA-165162 Phosphorylation of TSC2 by PKB TAS Homo sapiens 30616 R-HSA-165182 https://reactome.org/PathwayBrowser/#/R-HSA-165182 Phosphorylation of complexed TSC2 by PKB TAS Homo sapiens 30616 R-HSA-165692 https://reactome.org/PathwayBrowser/#/R-HSA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 TAS Homo sapiens 30616 R-HSA-165718 https://reactome.org/PathwayBrowser/#/R-HSA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) TAS Homo sapiens 30616 R-HSA-165726 https://reactome.org/PathwayBrowser/#/R-HSA-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 TAS Homo sapiens 30616 R-HSA-165758 https://reactome.org/PathwayBrowser/#/R-HSA-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 TAS Homo sapiens 30616 R-HSA-165766 https://reactome.org/PathwayBrowser/#/R-HSA-165766 Phosphorylation and activation of eIF4G by activated S6K1 TAS Homo sapiens 30616 R-HSA-165777 https://reactome.org/PathwayBrowser/#/R-HSA-165777 Phosphorylation and activation of eIF4B by activated S6K1 TAS Homo sapiens 30616 R-HSA-166119 https://reactome.org/PathwayBrowser/#/R-HSA-166119 First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal TAS Homo sapiens 30616 R-HSA-166245 https://reactome.org/PathwayBrowser/#/R-HSA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex TAS Homo sapiens 30616 R-HSA-166284 https://reactome.org/PathwayBrowser/#/R-HSA-166284 Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP TAS Homo sapiens 30616 R-HSA-166286 https://reactome.org/PathwayBrowser/#/R-HSA-166286 Multiple IRAK1 autophosphorylation steps TAS Homo sapiens 30616 R-HSA-166544 https://reactome.org/PathwayBrowser/#/R-HSA-166544 TrkA receptor autophosphorylates IEA Homo sapiens 30616 R-HSA-167019 https://reactome.org/PathwayBrowser/#/R-HSA-167019 SHC, complexed with TrkA, is tyrosine-phosphorylated IEA Homo sapiens 30616 R-HSA-167084 https://reactome.org/PathwayBrowser/#/R-HSA-167084 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Homo sapiens 30616 R-HSA-167097 https://reactome.org/PathwayBrowser/#/R-HSA-167097 HIV Promoter Opening: First Transition IEA Homo sapiens 30616 R-HSA-167098 https://reactome.org/PathwayBrowser/#/R-HSA-167098 Phosphorylation (Ser5) of RNA pol II CTD IEA Homo sapiens 30616 R-HSA-1671691 https://reactome.org/PathwayBrowser/#/R-HSA-1671691 PRLR-bound STAT5 is phosphorylated IEA Homo sapiens 30616 R-HSA-167191 https://reactome.org/PathwayBrowser/#/R-HSA-167191 Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex IEA Homo sapiens 30616 R-HSA-1675773 https://reactome.org/PathwayBrowser/#/R-HSA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane TAS Homo sapiens 30616 R-HSA-1675776 https://reactome.org/PathwayBrowser/#/R-HSA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane TAS Homo sapiens 30616 R-HSA-1675780 https://reactome.org/PathwayBrowser/#/R-HSA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane TAS Homo sapiens 30616 R-HSA-1675810 https://reactome.org/PathwayBrowser/#/R-HSA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane TAS Homo sapiens 30616 R-HSA-1675813 https://reactome.org/PathwayBrowser/#/R-HSA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane TAS Homo sapiens 30616 R-HSA-1675866 https://reactome.org/PathwayBrowser/#/R-HSA-1675866 PI is phosphorylated to PI5P by PIKFYVE at the late endosome membrane IEA Homo sapiens 30616 R-HSA-1675883 https://reactome.org/PathwayBrowser/#/R-HSA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane TAS Homo sapiens 30616 R-HSA-1675910 https://reactome.org/PathwayBrowser/#/R-HSA-1675910 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the late endosome membrane IEA Homo sapiens 30616 R-HSA-1675921 https://reactome.org/PathwayBrowser/#/R-HSA-1675921 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the Golgi membrane IEA Homo sapiens 30616 R-HSA-1675928 https://reactome.org/PathwayBrowser/#/R-HSA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane TAS Homo sapiens 30616 R-HSA-1675939 https://reactome.org/PathwayBrowser/#/R-HSA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane TAS Homo sapiens 30616 R-HSA-1675961 https://reactome.org/PathwayBrowser/#/R-HSA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane TAS Homo sapiens 30616 R-HSA-1675974 https://reactome.org/PathwayBrowser/#/R-HSA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane TAS Homo sapiens 30616 R-HSA-1676024 https://reactome.org/PathwayBrowser/#/R-HSA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane TAS Homo sapiens 30616 R-HSA-1676048 https://reactome.org/PathwayBrowser/#/R-HSA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane TAS Homo sapiens 30616 R-HSA-1676082 https://reactome.org/PathwayBrowser/#/R-HSA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane TAS Homo sapiens 30616 R-HSA-1676109 https://reactome.org/PathwayBrowser/#/R-HSA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane TAS Homo sapiens 30616 R-HSA-1676134 https://reactome.org/PathwayBrowser/#/R-HSA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane TAS Homo sapiens 30616 R-HSA-1676145 https://reactome.org/PathwayBrowser/#/R-HSA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane TAS Homo sapiens 30616 R-HSA-1676168 https://reactome.org/PathwayBrowser/#/R-HSA-1676168 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane IEA Homo sapiens 30616 R-HSA-1676185 https://reactome.org/PathwayBrowser/#/R-HSA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane TAS Homo sapiens 30616 R-HSA-1676206 https://reactome.org/PathwayBrowser/#/R-HSA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane TAS Homo sapiens 30616 R-HSA-167683 https://reactome.org/PathwayBrowser/#/R-HSA-167683 TrkA phosphorylates PLCG1 IEA Homo sapiens 30616 R-HSA-1678923 https://reactome.org/PathwayBrowser/#/R-HSA-1678923 TLR folding by chaperones GP96 and CNPY3 TAS Homo sapiens 30616 R-HSA-1678944 https://reactome.org/PathwayBrowser/#/R-HSA-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex TAS Homo sapiens 30616 R-HSA-168053 https://reactome.org/PathwayBrowser/#/R-HSA-168053 Phosphorylated MAPKs phosphorylate ATF-2 TAS Homo sapiens 30616 R-HSA-168136 https://reactome.org/PathwayBrowser/#/R-HSA-168136 Activated JNKs phosphorylate c-JUN TAS Homo sapiens 30616 R-HSA-168140 https://reactome.org/PathwayBrowser/#/R-HSA-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor TAS Homo sapiens 30616 R-HSA-168162 https://reactome.org/PathwayBrowser/#/R-HSA-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 TAS Homo sapiens 30616 R-HSA-168184 https://reactome.org/PathwayBrowser/#/R-HSA-168184 Activated TAK1 mediates phosphorylation of the IKK Complex TAS Homo sapiens 30616 R-HSA-168909 https://reactome.org/PathwayBrowser/#/R-HSA-168909 viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58 bind MAVS TAS Homo sapiens 30616 R-HSA-168910 https://reactome.org/PathwayBrowser/#/R-HSA-168910 RIP1 facilitates IKK complex phosphorylation TAS Homo sapiens 30616 R-HSA-168934 https://reactome.org/PathwayBrowser/#/R-HSA-168934 MAVS interacts with RIPK1 and FADD TAS Homo sapiens 30616 R-HSA-168935 https://reactome.org/PathwayBrowser/#/R-HSA-168935 viral dsRNA binds DDX58 TAS Homo sapiens 30616 R-HSA-169905 https://reactome.org/PathwayBrowser/#/R-HSA-169905 ARMS is phosphorylated by active TrkA receptor TAS Homo sapiens 30616 R-HSA-170026 https://reactome.org/PathwayBrowser/#/R-HSA-170026 Protons are translocated from the intermembrane space to the matrix TAS Homo sapiens 30616 R-HSA-170055 https://reactome.org/PathwayBrowser/#/R-HSA-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes TAS Homo sapiens 30616 R-HSA-170070 https://reactome.org/PathwayBrowser/#/R-HSA-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes TAS Homo sapiens 30616 R-HSA-170076 https://reactome.org/PathwayBrowser/#/R-HSA-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes TAS Homo sapiens 30616 R-HSA-170087 https://reactome.org/PathwayBrowser/#/R-HSA-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes TAS Homo sapiens 30616 R-HSA-170116 https://reactome.org/PathwayBrowser/#/R-HSA-170116 Myt-1 mediated phosphorylation of Cyclin A:Cdc2 IEA Homo sapiens 30616 R-HSA-170126 https://reactome.org/PathwayBrowser/#/R-HSA-170126 Phosphorylation of Cyclin B1 in the CRS domain TAS Homo sapiens 30616 R-HSA-170156 https://reactome.org/PathwayBrowser/#/R-HSA-170156 Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes IEA Homo sapiens 30616 R-HSA-170676 https://reactome.org/PathwayBrowser/#/R-HSA-170676 Adenylate cyclase converts ATP into cyclic AMP TAS Homo sapiens 30616 R-HSA-170704 https://reactome.org/PathwayBrowser/#/R-HSA-170704 Phosphorylation of DSIF by the P-TEFb(Cyclin T1:Cdk9) complex TAS Homo sapiens 30616 R-HSA-170706 https://reactome.org/PathwayBrowser/#/R-HSA-170706 Phosphorylation of NEFL by the P-TEFb(Cyclin T1:Cdk9) complex TAS Homo sapiens 30616 R-HSA-170843 https://reactome.org/PathwayBrowser/#/R-HSA-170843 TGFBR2 phosphorylates TGFBR1 TAS Homo sapiens 30616 R-HSA-170868 https://reactome.org/PathwayBrowser/#/R-HSA-170868 Activated type I receptor phosphorylates SMAD2/3 directly TAS Homo sapiens 30616 R-HSA-170977 https://reactome.org/PathwayBrowser/#/R-HSA-170977 FRS2 is phosphorylated by active TrkA receptor TAS Homo sapiens 30616 R-HSA-170991 https://reactome.org/PathwayBrowser/#/R-HSA-170991 SRC-1 autophosphorylates IEA Homo sapiens 30616 R-HSA-171011 https://reactome.org/PathwayBrowser/#/R-HSA-171011 Binding and activation of MAP Kinase IEA Homo sapiens 30616 R-HSA-174079 https://reactome.org/PathwayBrowser/#/R-HSA-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 TAS Homo sapiens 30616 R-HSA-174122 https://reactome.org/PathwayBrowser/#/R-HSA-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 TAS Homo sapiens 30616 R-HSA-174164 https://reactome.org/PathwayBrowser/#/R-HSA-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 TAS Homo sapiens 30616 R-HSA-174174 https://reactome.org/PathwayBrowser/#/R-HSA-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 TAS Homo sapiens 30616 R-HSA-174251 https://reactome.org/PathwayBrowser/#/R-HSA-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 TAS Homo sapiens 30616 R-HSA-174367 https://reactome.org/PathwayBrowser/#/R-HSA-174367 GCL ligates L-Glu to L-Cys TAS Homo sapiens 30616 R-HSA-174389 https://reactome.org/PathwayBrowser/#/R-HSA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS TAS Homo sapiens 30616 R-HSA-174391 https://reactome.org/PathwayBrowser/#/R-HSA-174391 MAT1A multimers transfer Ado from ATP to L-Met TAS Homo sapiens 30616 R-HSA-174392 https://reactome.org/PathwayBrowser/#/R-HSA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS TAS Homo sapiens 30616 R-HSA-174394 https://reactome.org/PathwayBrowser/#/R-HSA-174394 GSS:Mg2+ dimer synthesizes GSH TAS Homo sapiens 30616 R-HSA-174438 https://reactome.org/PathwayBrowser/#/R-HSA-174438 Formation of the Flap Intermediate on the C-strand TAS Homo sapiens 30616 R-HSA-174439 https://reactome.org/PathwayBrowser/#/R-HSA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere TAS Homo sapiens 30616 R-HSA-176116 https://reactome.org/PathwayBrowser/#/R-HSA-176116 Recruitment and activation of Chk1 TAS Homo sapiens 30616 R-HSA-176298 https://reactome.org/PathwayBrowser/#/R-HSA-176298 Activation of claspin TAS Homo sapiens 30616 R-HSA-177157 https://reactome.org/PathwayBrowser/#/R-HSA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-177275 https://reactome.org/PathwayBrowser/#/R-HSA-177275 PKA phosphorylates DARPP-32 on Thr34 TAS Homo sapiens 30616 R-HSA-177284 https://reactome.org/PathwayBrowser/#/R-HSA-177284 PKA phosphorylates PDE4B TAS Homo sapiens 30616 R-HSA-177692 https://reactome.org/PathwayBrowser/#/R-HSA-177692 Activation of recruited TAK1 within the activated TLR3 complex TAS Homo sapiens 30616 R-HSA-177930 https://reactome.org/PathwayBrowser/#/R-HSA-177930 GAB1 phosphorylation by EGFR kinase TAS Homo sapiens 30616 R-HSA-177933 https://reactome.org/PathwayBrowser/#/R-HSA-177933 SHC1 phosphorylation by phosphorylated EGFR TAS Homo sapiens 30616 R-HSA-177934 https://reactome.org/PathwayBrowser/#/R-HSA-177934 EGFR autophosphorylation TAS Homo sapiens 30616 R-HSA-177937 https://reactome.org/PathwayBrowser/#/R-HSA-177937 Phosphorylation of EGFR by SRC kinase TAS Homo sapiens 30616 R-HSA-177939 https://reactome.org/PathwayBrowser/#/R-HSA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) TAS Homo sapiens 30616 R-HSA-182969 https://reactome.org/PathwayBrowser/#/R-HSA-182969 Phosphorylation of CBL (EGFR:CBL) TAS Homo sapiens 30616 R-HSA-183058 https://reactome.org/PathwayBrowser/#/R-HSA-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) TAS Homo sapiens 30616 R-HSA-1839065 https://reactome.org/PathwayBrowser/#/R-HSA-1839065 Phosphorylation of cytosolic FGFR1 fusion dimers TAS Homo sapiens 30616 R-HSA-1839067 https://reactome.org/PathwayBrowser/#/R-HSA-1839067 Phosphorylation of BCR moiety of BCR-FGFR1 TAS Homo sapiens 30616 R-HSA-1839091 https://reactome.org/PathwayBrowser/#/R-HSA-1839091 Cytosolic FGFR1 fusion protein-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-1839098 https://reactome.org/PathwayBrowser/#/R-HSA-1839098 Activated FGFR1 mutants and fusions phosphorylate PLCG1 TAS Homo sapiens 30616 R-HSA-1839107 https://reactome.org/PathwayBrowser/#/R-HSA-1839107 BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3. TAS Homo sapiens 30616 R-HSA-1839110 https://reactome.org/PathwayBrowser/#/R-HSA-1839110 p-BCR-p-FGFR1 phosphorylates GAB2 TAS Homo sapiens 30616 R-HSA-1839112 https://reactome.org/PathwayBrowser/#/R-HSA-1839112 Phosphorylation of STAT5 by cytosolic FGFR1 fusions TAS Homo sapiens 30616 R-HSA-1855153 https://reactome.org/PathwayBrowser/#/R-HSA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol TAS Homo sapiens 30616 R-HSA-1855157 https://reactome.org/PathwayBrowser/#/R-HSA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus TAS Homo sapiens 30616 R-HSA-1855158 https://reactome.org/PathwayBrowser/#/R-HSA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol TAS Homo sapiens 30616 R-HSA-1855162 https://reactome.org/PathwayBrowser/#/R-HSA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol TAS Homo sapiens 30616 R-HSA-1855169 https://reactome.org/PathwayBrowser/#/R-HSA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 30616 R-HSA-1855172 https://reactome.org/PathwayBrowser/#/R-HSA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol TAS Homo sapiens 30616 R-HSA-1855176 https://reactome.org/PathwayBrowser/#/R-HSA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus TAS Homo sapiens 30616 R-HSA-1855179 https://reactome.org/PathwayBrowser/#/R-HSA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol TAS Homo sapiens 30616 R-HSA-1855181 https://reactome.org/PathwayBrowser/#/R-HSA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus TAS Homo sapiens 30616 R-HSA-1855182 https://reactome.org/PathwayBrowser/#/R-HSA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol TAS Homo sapiens 30616 R-HSA-1855185 https://reactome.org/PathwayBrowser/#/R-HSA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 30616 R-HSA-1855193 https://reactome.org/PathwayBrowser/#/R-HSA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol TAS Homo sapiens 30616 R-HSA-1855194 https://reactome.org/PathwayBrowser/#/R-HSA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol TAS Homo sapiens 30616 R-HSA-1855197 https://reactome.org/PathwayBrowser/#/R-HSA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 30616 R-HSA-1855206 https://reactome.org/PathwayBrowser/#/R-HSA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 30616 R-HSA-1855207 https://reactome.org/PathwayBrowser/#/R-HSA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus TAS Homo sapiens 30616 R-HSA-1855216 https://reactome.org/PathwayBrowser/#/R-HSA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol TAS Homo sapiens 30616 R-HSA-1855223 https://reactome.org/PathwayBrowser/#/R-HSA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol TAS Homo sapiens 30616 R-HSA-1855224 https://reactome.org/PathwayBrowser/#/R-HSA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus TAS Homo sapiens 30616 R-HSA-1855227 https://reactome.org/PathwayBrowser/#/R-HSA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol TAS Homo sapiens 30616 R-HSA-1855228 https://reactome.org/PathwayBrowser/#/R-HSA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 30616 R-HSA-1855230 https://reactome.org/PathwayBrowser/#/R-HSA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus TAS Homo sapiens 30616 R-HSA-1855233 https://reactome.org/PathwayBrowser/#/R-HSA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus TAS Homo sapiens 30616 R-HSA-1861595 https://reactome.org/PathwayBrowser/#/R-HSA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner TAS Homo sapiens 30616 R-HSA-186786 https://reactome.org/PathwayBrowser/#/R-HSA-186786 Autophosphorylation of PDGF beta receptors TAS Homo sapiens 30616 R-HSA-186800 https://reactome.org/PathwayBrowser/#/R-HSA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-187520 https://reactome.org/PathwayBrowser/#/R-HSA-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 TAS Homo sapiens 30616 R-HSA-187688 https://reactome.org/PathwayBrowser/#/R-HSA-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 TAS Homo sapiens 30616 R-HSA-187916 https://reactome.org/PathwayBrowser/#/R-HSA-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 TAS Homo sapiens 30616 R-HSA-187948 https://reactome.org/PathwayBrowser/#/R-HSA-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 TAS Homo sapiens 30616 R-HSA-187949 https://reactome.org/PathwayBrowser/#/R-HSA-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 TAS Homo sapiens 30616 R-HSA-187959 https://reactome.org/PathwayBrowser/#/R-HSA-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) TAS Homo sapiens 30616 R-HSA-188350 https://reactome.org/PathwayBrowser/#/R-HSA-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 TAS Homo sapiens 30616 R-HSA-188390 https://reactome.org/PathwayBrowser/#/R-HSA-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 TAS Homo sapiens 30616 R-HSA-1888198 https://reactome.org/PathwayBrowser/#/R-HSA-1888198 FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 TAS Homo sapiens 30616 R-HSA-190326 https://reactome.org/PathwayBrowser/#/R-HSA-190326 Autocatalytic phosphorylation of FGFR4 TAS Homo sapiens 30616 R-HSA-190385 https://reactome.org/PathwayBrowser/#/R-HSA-190385 Autocatalytic phosphorylation of FGFR3b TAS Homo sapiens 30616 R-HSA-190388 https://reactome.org/PathwayBrowser/#/R-HSA-190388 Autocatalytic phosphorylation of FGFR3c TAS Homo sapiens 30616 R-HSA-190408 https://reactome.org/PathwayBrowser/#/R-HSA-190408 Autocatalytic phosphorylation of FGFR2b TAS Homo sapiens 30616 R-HSA-190413 https://reactome.org/PathwayBrowser/#/R-HSA-190413 Autocatalytic phosphorylation of FGFR2c TAS Homo sapiens 30616 R-HSA-190427 https://reactome.org/PathwayBrowser/#/R-HSA-190427 Autocatalytic phosphorylation of FGFR1b TAS Homo sapiens 30616 R-HSA-190429 https://reactome.org/PathwayBrowser/#/R-HSA-190429 Autocatalytic phosphorylation of FGFR1c TAS Homo sapiens 30616 R-HSA-191062 https://reactome.org/PathwayBrowser/#/R-HSA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c TAS Homo sapiens 30616 R-HSA-1912391 https://reactome.org/PathwayBrowser/#/R-HSA-1912391 NICD1 is phosphorylated by CDK8 IEA Homo sapiens 30616 R-HSA-191380 https://reactome.org/PathwayBrowser/#/R-HSA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate TAS Homo sapiens 30616 R-HSA-191414 https://reactome.org/PathwayBrowser/#/R-HSA-191414 MVD decarboxylates MVA5PP to IPPP TAS Homo sapiens 30616 R-HSA-191422 https://reactome.org/PathwayBrowser/#/R-HSA-191422 Mevalonate-5-phosphate is further phosphorylated. TAS Homo sapiens 30616 R-HSA-191636 https://reactome.org/PathwayBrowser/#/R-HSA-191636 Phosphorylation of Cx43 by c-src TAS Homo sapiens 30616 R-HSA-192137 https://reactome.org/PathwayBrowser/#/R-HSA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 30616 R-HSA-193362 https://reactome.org/PathwayBrowser/#/R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-193401 https://reactome.org/PathwayBrowser/#/R-HSA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 30616 R-HSA-193407 https://reactome.org/PathwayBrowser/#/R-HSA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 30616 R-HSA-193424 https://reactome.org/PathwayBrowser/#/R-HSA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 30616 R-HSA-193647 https://reactome.org/PathwayBrowser/#/R-HSA-193647 IRAK is activated IEA Homo sapiens 30616 R-HSA-193703 https://reactome.org/PathwayBrowser/#/R-HSA-193703 IKKbeta is activated TAS Homo sapiens 30616 R-HSA-193705 https://reactome.org/PathwayBrowser/#/R-HSA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate TAS Homo sapiens 30616 R-HSA-193711 https://reactome.org/PathwayBrowser/#/R-HSA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 30616 R-HSA-193727 https://reactome.org/PathwayBrowser/#/R-HSA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 30616 R-HSA-193743 https://reactome.org/PathwayBrowser/#/R-HSA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 30616 R-HSA-193766 https://reactome.org/PathwayBrowser/#/R-HSA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 30616 R-HSA-194153 https://reactome.org/PathwayBrowser/#/R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-195275 https://reactome.org/PathwayBrowser/#/R-HSA-195275 Phosphorylation of APC component of the destruction complex TAS Homo sapiens 30616 R-HSA-195283 https://reactome.org/PathwayBrowser/#/R-HSA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 TAS Homo sapiens 30616 R-HSA-195287 https://reactome.org/PathwayBrowser/#/R-HSA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 TAS Homo sapiens 30616 R-HSA-195300 https://reactome.org/PathwayBrowser/#/R-HSA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 TAS Homo sapiens 30616 R-HSA-195318 https://reactome.org/PathwayBrowser/#/R-HSA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha TAS Homo sapiens 30616 R-HSA-1963581 https://reactome.org/PathwayBrowser/#/R-HSA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers TAS Homo sapiens 30616 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 30616 R-HSA-1963586 https://reactome.org/PathwayBrowser/#/R-HSA-1963586 SRC family kinases phosphorylate ERBB2 TAS Homo sapiens 30616 R-HSA-196753 https://reactome.org/PathwayBrowser/#/R-HSA-196753 2xPPCS ligates PPanK with Cys TAS Homo sapiens 30616 R-HSA-196754 https://reactome.org/PathwayBrowser/#/R-HSA-196754 COASY transfers an adenylyl group from ATP to PPANT TAS Homo sapiens 30616 R-HSA-196761 https://reactome.org/PathwayBrowser/#/R-HSA-196761 2xTPK1:Mg2+ phosphorylates THMN TAS Homo sapiens 30616 R-HSA-196773 https://reactome.org/PathwayBrowser/#/R-HSA-196773 COASY phosphorylates DP-CoA TAS Homo sapiens 30616 R-HSA-196857 https://reactome.org/PathwayBrowser/#/R-HSA-196857 PANK2 phosphorylates PanK TAS Homo sapiens 30616 R-HSA-196929 https://reactome.org/PathwayBrowser/#/R-HSA-196929 FLAD1 phosphorylates FMN TAS Homo sapiens 30616 R-HSA-196964 https://reactome.org/PathwayBrowser/#/R-HSA-196964 RFK:Mg2+ phosphorylates RIB TAS Homo sapiens 30616 R-HSA-197198 https://reactome.org/PathwayBrowser/#/R-HSA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ TAS Homo sapiens 30616 R-HSA-197235 https://reactome.org/PathwayBrowser/#/R-HSA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 30616 R-HSA-197271 https://reactome.org/PathwayBrowser/#/R-HSA-197271 NADSYN1 hexamer amidates NAAD to NAD+ TAS Homo sapiens 30616 R-HSA-197958 https://reactome.org/PathwayBrowser/#/R-HSA-197958 FPGS-2 transforms THF to THFPG TAS Homo sapiens 30616 R-HSA-1982066 https://reactome.org/PathwayBrowser/#/R-HSA-1982066 Ligand-independent phosphorylation of overexpressed FGFR1 TAS Homo sapiens 30616 R-HSA-198266 https://reactome.org/PathwayBrowser/#/R-HSA-198266 PI3K produces PIP3 and other phosphatidyl inositides TAS Homo sapiens 30616 R-HSA-198270 https://reactome.org/PathwayBrowser/#/R-HSA-198270 PDPK1 phosphorylates AKT at T308 TAS Homo sapiens 30616 R-HSA-198295 https://reactome.org/PathwayBrowser/#/R-HSA-198295 TRKA phosphorylates IRS IEA Homo sapiens 30616 R-HSA-198314 https://reactome.org/PathwayBrowser/#/R-HSA-198314 DAG stimulates protein kinase C-delta TAS Homo sapiens 30616 R-HSA-198347 https://reactome.org/PathwayBrowser/#/R-HSA-198347 AKT phosphorylates BAD IEA Homo sapiens 30616 R-HSA-198371 https://reactome.org/PathwayBrowser/#/R-HSA-198371 AKT phosphorylates GSK3 IEA Homo sapiens 30616 R-HSA-198599 https://reactome.org/PathwayBrowser/#/R-HSA-198599 AKT phosphorylates MDM2 TAS Homo sapiens 30616 R-HSA-198609 https://reactome.org/PathwayBrowser/#/R-HSA-198609 AKT phosphorylates TSC2, inhibiting it TAS Homo sapiens 30616 R-HSA-198611 https://reactome.org/PathwayBrowser/#/R-HSA-198611 AKT phosphorylates IKKalpha TAS Homo sapiens 30616 R-HSA-198613 https://reactome.org/PathwayBrowser/#/R-HSA-198613 AKT phosphorylates p21Cip1 and p27Kip1 TAS Homo sapiens 30616 R-HSA-198621 https://reactome.org/PathwayBrowser/#/R-HSA-198621 AKT phosphorylates caspase-9 TAS Homo sapiens 30616 R-HSA-198640 https://reactome.org/PathwayBrowser/#/R-HSA-198640 TORC2 (mTOR) phosphorylates AKT at S473 TAS Homo sapiens 30616 R-HSA-198669 https://reactome.org/PathwayBrowser/#/R-HSA-198669 p38MAPK phosphorylates MSK1 TAS Homo sapiens 30616 R-HSA-198731 https://reactome.org/PathwayBrowser/#/R-HSA-198731 ERK1/2 activates ELK1 IEA Homo sapiens 30616 R-HSA-198732 https://reactome.org/PathwayBrowser/#/R-HSA-198732 STAT3 activation IEA Homo sapiens 30616 R-HSA-198733 https://reactome.org/PathwayBrowser/#/R-HSA-198733 ERK5 is activated IEA Homo sapiens 30616 R-HSA-198746 https://reactome.org/PathwayBrowser/#/R-HSA-198746 ERK1/2/5 activate RSK1/2/3 TAS Homo sapiens 30616 R-HSA-198756 https://reactome.org/PathwayBrowser/#/R-HSA-198756 ERK1/2 phosphorylates MSK1 TAS Homo sapiens 30616 R-HSA-199203 https://reactome.org/PathwayBrowser/#/R-HSA-199203 PANK1/3 phosphorylate PanK TAS Homo sapiens 30616 R-HSA-199298 https://reactome.org/PathwayBrowser/#/R-HSA-199298 AKT phosphorylates CREB1 TAS Homo sapiens 30616 R-HSA-199299 https://reactome.org/PathwayBrowser/#/R-HSA-199299 AKT phosphorylates FOXO transcription factors TAS Homo sapiens 30616 R-HSA-199839 https://reactome.org/PathwayBrowser/#/R-HSA-199839 AKT can phosphorylate RSK TAS Homo sapiens 30616 R-HSA-199863 https://reactome.org/PathwayBrowser/#/R-HSA-199863 AKT can phosphorylate NR4A1 (NUR77) TAS Homo sapiens 30616 R-HSA-199895 https://reactome.org/PathwayBrowser/#/R-HSA-199895 RSK1/2/3 phosphorylates CREB at Serine 119 TAS Homo sapiens 30616 R-HSA-199910 https://reactome.org/PathwayBrowser/#/R-HSA-199910 MSK1 activates ATF1 TAS Homo sapiens 30616 R-HSA-199917 https://reactome.org/PathwayBrowser/#/R-HSA-199917 MAPKAPK2 phosphorylates CREB at Serine 133 TAS Homo sapiens 30616 R-HSA-199929 https://reactome.org/PathwayBrowser/#/R-HSA-199929 ERK5 activates the transcription factor MEF2 IEA Homo sapiens 30616 R-HSA-199935 https://reactome.org/PathwayBrowser/#/R-HSA-199935 MSK1 activates CREB TAS Homo sapiens 30616 R-HSA-200143 https://reactome.org/PathwayBrowser/#/R-HSA-200143 AKT phosphorylates AKT1S1 (PRAS40) TAS Homo sapiens 30616 R-HSA-200318 https://reactome.org/PathwayBrowser/#/R-HSA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] TAS Homo sapiens 30616 R-HSA-200326 https://reactome.org/PathwayBrowser/#/R-HSA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] TAS Homo sapiens 30616 R-HSA-200421 https://reactome.org/PathwayBrowser/#/R-HSA-200421 Activation of cytosolic AMPK by phosphorylation TAS Homo sapiens 30616 R-HSA-200423 https://reactome.org/PathwayBrowser/#/R-HSA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis TAS Homo sapiens 30616 R-HSA-200474 https://reactome.org/PathwayBrowser/#/R-HSA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 30616 R-HSA-200512 https://reactome.org/PathwayBrowser/#/R-HSA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 30616 R-HSA-200555 https://reactome.org/PathwayBrowser/#/R-HSA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate TAS Homo sapiens 30616 R-HSA-200681 https://reactome.org/PathwayBrowser/#/R-HSA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG TAS Homo sapiens 30616 R-HSA-200682 https://reactome.org/PathwayBrowser/#/R-HSA-200682 Mitochondrial FPGS-1 transforms THF to THFPG TAS Homo sapiens 30616 R-HSA-200711 https://reactome.org/PathwayBrowser/#/R-HSA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG TAS Homo sapiens 30616 R-HSA-201035 https://reactome.org/PathwayBrowser/#/R-HSA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA TAS Homo sapiens 30616 R-HSA-2012073 https://reactome.org/PathwayBrowser/#/R-HSA-2012073 Autocatalytic phosphorylation of FGFR3c P250R mutant TAS Homo sapiens 30616 R-HSA-2012082 https://reactome.org/PathwayBrowser/#/R-HSA-2012082 Autocatalytic phosphorylation of FGFR3 cysteine mutants TAS Homo sapiens 30616 R-HSA-2012087 https://reactome.org/PathwayBrowser/#/R-HSA-2012087 Autocatalytic phosphorylation of FGFR4 Y367C mutant TAS Homo sapiens 30616 R-HSA-201443 https://reactome.org/PathwayBrowser/#/R-HSA-201443 Type II receptor phosphorylates type I receptor TAS Homo sapiens 30616 R-HSA-201476 https://reactome.org/PathwayBrowser/#/R-HSA-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly TAS Homo sapiens 30616 R-HSA-201510 https://reactome.org/PathwayBrowser/#/R-HSA-201510 PI3K synthesizes PIP3 downstream of ALK TAS Homo sapiens 30616 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 30616 R-HSA-201677 https://reactome.org/PathwayBrowser/#/R-HSA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta TAS Homo sapiens 30616 R-HSA-201691 https://reactome.org/PathwayBrowser/#/R-HSA-201691 Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI IEA Homo sapiens 30616 R-HSA-201717 https://reactome.org/PathwayBrowser/#/R-HSA-201717 CSNK2-mediated phosphorylation of DVL TAS Homo sapiens 30616 R-HSA-202111 https://reactome.org/PathwayBrowser/#/R-HSA-202111 AKT1 phosphorylates eNOS TAS Homo sapiens 30616 R-HSA-202165 https://reactome.org/PathwayBrowser/#/R-HSA-202165 Phosphorylation of ITAM motifs in CD3 complexes TAS Homo sapiens 30616 R-HSA-202168 https://reactome.org/PathwayBrowser/#/R-HSA-202168 Phosphorylation of ZAP-70 by Lck TAS Homo sapiens 30616 R-HSA-202174 https://reactome.org/PathwayBrowser/#/R-HSA-202174 Activation of ZAP-70 TAS Homo sapiens 30616 R-HSA-202216 https://reactome.org/PathwayBrowser/#/R-HSA-202216 Phosphorylation of SLP-76 TAS Homo sapiens 30616 R-HSA-202222 https://reactome.org/PathwayBrowser/#/R-HSA-202222 Phosphorylation of PKC theta TAS Homo sapiens 30616 R-HSA-202233 https://reactome.org/PathwayBrowser/#/R-HSA-202233 Inactivation of Lck by Csk TAS Homo sapiens 30616 R-HSA-202245 https://reactome.org/PathwayBrowser/#/R-HSA-202245 Phosphorylation of TBSMs in LAT TAS Homo sapiens 30616 R-HSA-202248 https://reactome.org/PathwayBrowser/#/R-HSA-202248 Phosphorylation of PLC-gamma1 TAS Homo sapiens 30616 R-HSA-202291 https://reactome.org/PathwayBrowser/#/R-HSA-202291 Activation of Lck TAS Homo sapiens 30616 R-HSA-202307 https://reactome.org/PathwayBrowser/#/R-HSA-202307 Change of PKC theta conformation TAS Homo sapiens 30616 R-HSA-2023455 https://reactome.org/PathwayBrowser/#/R-HSA-2023455 Autocatalytic phosphorylation of FGFR1c P252X mutant dimers TAS Homo sapiens 30616 R-HSA-2023460 https://reactome.org/PathwayBrowser/#/R-HSA-2023460 Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity TAS Homo sapiens 30616 R-HSA-202365 https://reactome.org/PathwayBrowser/#/R-HSA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-202437 https://reactome.org/PathwayBrowser/#/R-HSA-202437 Phosphorylation of CARMA1 TAS Homo sapiens 30616 R-HSA-202459 https://reactome.org/PathwayBrowser/#/R-HSA-202459 Phosphorylation of Bcl10 TAS Homo sapiens 30616 R-HSA-202500 https://reactome.org/PathwayBrowser/#/R-HSA-202500 Activation of IKK complex TAS Homo sapiens 30616 R-HSA-202510 https://reactome.org/PathwayBrowser/#/R-HSA-202510 Activation of TAK1-TAB2 complex TAS Homo sapiens 30616 R-HSA-202541 https://reactome.org/PathwayBrowser/#/R-HSA-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB TAS Homo sapiens 30616 R-HSA-2028284 https://reactome.org/PathwayBrowser/#/R-HSA-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 TAS Homo sapiens 30616 R-HSA-2028555 https://reactome.org/PathwayBrowser/#/R-HSA-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) TAS Homo sapiens 30616 R-HSA-2028583 https://reactome.org/PathwayBrowser/#/R-HSA-2028583 Phosphorylation of YAP by LATS2 TAS Homo sapiens 30616 R-HSA-2028589 https://reactome.org/PathwayBrowser/#/R-HSA-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) TAS Homo sapiens 30616 R-HSA-2028591 https://reactome.org/PathwayBrowser/#/R-HSA-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 TAS Homo sapiens 30616 R-HSA-2028598 https://reactome.org/PathwayBrowser/#/R-HSA-2028598 Phosphorylation of YAP by LATS1 TAS Homo sapiens 30616 R-HSA-2028629 https://reactome.org/PathwayBrowser/#/R-HSA-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) TAS Homo sapiens 30616 R-HSA-2028635 https://reactome.org/PathwayBrowser/#/R-HSA-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) TAS Homo sapiens 30616 R-HSA-2028661 https://reactome.org/PathwayBrowser/#/R-HSA-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 TAS Homo sapiens 30616 R-HSA-2028670 https://reactome.org/PathwayBrowser/#/R-HSA-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N TAS Homo sapiens 30616 R-HSA-2028673 https://reactome.org/PathwayBrowser/#/R-HSA-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N TAS Homo sapiens 30616 R-HSA-2028675 https://reactome.org/PathwayBrowser/#/R-HSA-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N TAS Homo sapiens 30616 R-HSA-2028679 https://reactome.org/PathwayBrowser/#/R-HSA-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N TAS Homo sapiens 30616 R-HSA-2029268 https://reactome.org/PathwayBrowser/#/R-HSA-2029268 Phosphorylation and activation of PLCG TAS Homo sapiens 30616 R-HSA-2029271 https://reactome.org/PathwayBrowser/#/R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-2029449 https://reactome.org/PathwayBrowser/#/R-HSA-2029449 Phosphorylation of SYK by Src kinases IEA Homo sapiens 30616 R-HSA-2029453 https://reactome.org/PathwayBrowser/#/R-HSA-2029453 Phosphorylation of VAV TAS Homo sapiens 30616 R-HSA-2029454 https://reactome.org/PathwayBrowser/#/R-HSA-2029454 Autophosphorylation of PAK1 TAS Homo sapiens 30616 R-HSA-2029459 https://reactome.org/PathwayBrowser/#/R-HSA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts TAS Homo sapiens 30616 R-HSA-2029460 https://reactome.org/PathwayBrowser/#/R-HSA-2029460 PAK1 phosphorylates LIMK1 TAS Homo sapiens 30616 R-HSA-2029466 https://reactome.org/PathwayBrowser/#/R-HSA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin TAS Homo sapiens 30616 R-HSA-2029469 https://reactome.org/PathwayBrowser/#/R-HSA-2029469 p-ERK phosphorylates WAVEs and ABI TAS Homo sapiens 30616 R-HSA-2029473 https://reactome.org/PathwayBrowser/#/R-HSA-2029473 Branching and elongation of mother and daughter filaments TAS Homo sapiens 30616 R-HSA-2029476 https://reactome.org/PathwayBrowser/#/R-HSA-2029476 Role of myosins in phagosome formation TAS Homo sapiens 30616 R-HSA-2029984 https://reactome.org/PathwayBrowser/#/R-HSA-2029984 Autocatalytic phosphorylation of FGFR2 ligand-independent mutants TAS Homo sapiens 30616 R-HSA-2029989 https://reactome.org/PathwayBrowser/#/R-HSA-2029989 Autocatalytic phosphorylation of overexpressed FGFR2 variants TAS Homo sapiens 30616 R-HSA-203070 https://reactome.org/PathwayBrowser/#/R-HSA-203070 Association of profilin with monomeric actin TAS Homo sapiens 30616 R-HSA-2033485 https://reactome.org/PathwayBrowser/#/R-HSA-2033485 Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity TAS Homo sapiens 30616 R-HSA-2033486 https://reactome.org/PathwayBrowser/#/R-HSA-2033486 Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding TAS Homo sapiens 30616 R-HSA-2033488 https://reactome.org/PathwayBrowser/#/R-HSA-2033488 Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding TAS Homo sapiens 30616 R-HSA-2033490 https://reactome.org/PathwayBrowser/#/R-HSA-2033490 Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity TAS Homo sapiens 30616 R-HSA-2038387 https://reactome.org/PathwayBrowser/#/R-HSA-2038387 Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants TAS Homo sapiens 30616 R-HSA-2038944 https://reactome.org/PathwayBrowser/#/R-HSA-2038944 Autocatalytic phosphorylation of FGFR4 mutants with enhanced kinase activity TAS Homo sapiens 30616 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 30616 R-HSA-2046085 https://reactome.org/PathwayBrowser/#/R-HSA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA TAS Homo sapiens 30616 R-HSA-2046087 https://reactome.org/PathwayBrowser/#/R-HSA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes TAS Homo sapiens 30616 R-HSA-2046093 https://reactome.org/PathwayBrowser/#/R-HSA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes TAS Homo sapiens 30616 R-HSA-2046098 https://reactome.org/PathwayBrowser/#/R-HSA-2046098 Activation of linoleic acid to linoleoyl-CoA TAS Homo sapiens 30616 R-HSA-204949 https://reactome.org/PathwayBrowser/#/R-HSA-204949 NRIF and TRAF6 may activate JNK IEA Homo sapiens 30616 R-HSA-205075 https://reactome.org/PathwayBrowser/#/R-HSA-205075 JNK phosphorylates BIM, BAD and other targets TAS Homo sapiens 30616 R-HSA-205132 https://reactome.org/PathwayBrowser/#/R-HSA-205132 NRAGE activates JNK IEA Homo sapiens 30616 R-HSA-205136 https://reactome.org/PathwayBrowser/#/R-HSA-205136 GTP-bound RAC contributes to JNK activation TAS Homo sapiens 30616 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 30616 R-HSA-2060328 https://reactome.org/PathwayBrowser/#/R-HSA-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 TAS Homo sapiens 30616 R-HSA-209087 https://reactome.org/PathwayBrowser/#/R-HSA-209087 IKBA is phosphorylated by Phospho IKKB kinase TAS Homo sapiens 30616 R-HSA-210291 https://reactome.org/PathwayBrowser/#/R-HSA-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src TAS Homo sapiens 30616 R-HSA-210872 https://reactome.org/PathwayBrowser/#/R-HSA-210872 Trans-phosphorylation of Tie2 IEA Homo sapiens 30616 R-HSA-211164 https://reactome.org/PathwayBrowser/#/R-HSA-211164 AKT phosphorylates FOXO1A TAS Homo sapiens 30616 R-HSA-211583 https://reactome.org/PathwayBrowser/#/R-HSA-211583 Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197 IEA Homo sapiens 30616 R-HSA-211650 https://reactome.org/PathwayBrowser/#/R-HSA-211650 Autophosphorylation of PAK-2p34 in the activation loop IEA Homo sapiens 30616 R-HSA-212710 https://reactome.org/PathwayBrowser/#/R-HSA-212710 EGFR activates PLC-gamma1 by phosphorylation TAS Homo sapiens 30616 R-HSA-2130194 https://reactome.org/PathwayBrowser/#/R-HSA-2130194 ABL phosphorylates WAVEs TAS Homo sapiens 30616 R-HSA-2134532 https://reactome.org/PathwayBrowser/#/R-HSA-2134532 TGFBR2 phosphorylates TGFBR1 and PARD6A IEA Homo sapiens 30616 R-HSA-2161506 https://reactome.org/PathwayBrowser/#/R-HSA-2161506 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 30616 R-HSA-2161538 https://reactome.org/PathwayBrowser/#/R-HSA-2161538 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 30616 R-HSA-2162092 https://reactome.org/PathwayBrowser/#/R-HSA-2162092 carbovir monophosphate + ATP => carbovir diphosphate + ADP IEA Homo sapiens 30616 R-HSA-2162096 https://reactome.org/PathwayBrowser/#/R-HSA-2162096 carbovir diphosphate + ATP => carbovir triphosphate + ADP IEA Homo sapiens 30616 R-HSA-216723 https://reactome.org/PathwayBrowser/#/R-HSA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 30616 R-HSA-216757 https://reactome.org/PathwayBrowser/#/R-HSA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane TAS Homo sapiens 30616 R-HSA-2168079 https://reactome.org/PathwayBrowser/#/R-HSA-2168079 MASTL (GWL) phosphorylates ARPP19 TAS Homo sapiens 30616 R-HSA-2172183 https://reactome.org/PathwayBrowser/#/R-HSA-2172183 Phosphorylation of GORASP1, GOLGA2 and RAB1A by CDK1:CCNB IEA Homo sapiens 30616 R-HSA-2176475 https://reactome.org/PathwayBrowser/#/R-HSA-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 TAS Homo sapiens 30616 R-HSA-2197690 https://reactome.org/PathwayBrowser/#/R-HSA-2197690 Detachment of WASP/WAVE TAS Homo sapiens 30616 R-HSA-2197698 https://reactome.org/PathwayBrowser/#/R-HSA-2197698 Src phosphorylate WASP,N-WASP TAS Homo sapiens 30616 R-HSA-2201322 https://reactome.org/PathwayBrowser/#/R-HSA-2201322 TIRAP is phosphorylated by BTK TAS Homo sapiens 30616 R-HSA-2213248 https://reactome.org/PathwayBrowser/#/R-HSA-2213248 Transport of antigen loaded MHC II molecules to surface TAS Homo sapiens 30616 R-HSA-2214351 https://reactome.org/PathwayBrowser/#/R-HSA-2214351 PLK1 phosphorylates GORASP1 TAS Homo sapiens 30616 R-HSA-2220971 https://reactome.org/PathwayBrowser/#/R-HSA-2220971 CDK8 phosphorylates NICD1 PEST domain mutants TAS Homo sapiens 30616 R-HSA-2243938 https://reactome.org/PathwayBrowser/#/R-HSA-2243938 AKT1 E17K mutant is phosphorylated by TORC2 complex TAS Homo sapiens 30616 R-HSA-2243942 https://reactome.org/PathwayBrowser/#/R-HSA-2243942 PDPK1 phosphorylates AKT1 E17K mutant TAS Homo sapiens 30616 R-HSA-2245218 https://reactome.org/PathwayBrowser/#/R-HSA-2245218 CDK1 phosphorylates PHF8 TAS Homo sapiens 30616 R-HSA-2267372 https://reactome.org/PathwayBrowser/#/R-HSA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 TAS Homo sapiens 30616 R-HSA-2294580 https://reactome.org/PathwayBrowser/#/R-HSA-2294580 PLK1 hyperphosphorylates Condensin II complex TAS Homo sapiens 30616 R-HSA-2294600 https://reactome.org/PathwayBrowser/#/R-HSA-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 TAS Homo sapiens 30616 R-HSA-2316434 https://reactome.org/PathwayBrowser/#/R-HSA-2316434 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-2394007 https://reactome.org/PathwayBrowser/#/R-HSA-2394007 PI3K gain of function mutants phosphorylate PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-2395412 https://reactome.org/PathwayBrowser/#/R-HSA-2395412 Phosphorylation of SYK TAS Homo sapiens 30616 R-HSA-2395439 https://reactome.org/PathwayBrowser/#/R-HSA-2395439 Phosphorylation of DAP12 IEA Homo sapiens 30616 R-HSA-2395801 https://reactome.org/PathwayBrowser/#/R-HSA-2395801 Phosphorylation of LAT by p-SYK TAS Homo sapiens 30616 R-HSA-2396002 https://reactome.org/PathwayBrowser/#/R-HSA-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex TAS Homo sapiens 30616 R-HSA-2396007 https://reactome.org/PathwayBrowser/#/R-HSA-2396007 IRF3 is phosphorylated by TBK1 TAS Homo sapiens 30616 R-HSA-2396594 https://reactome.org/PathwayBrowser/#/R-HSA-2396594 Phosphorylation of SLP-76 by p-SYK TAS Homo sapiens 30616 R-HSA-2399941 https://reactome.org/PathwayBrowser/#/R-HSA-2399941 AKT1 E17K mutant phosphorylates BAD TAS Homo sapiens 30616 R-HSA-2399966 https://reactome.org/PathwayBrowser/#/R-HSA-2399966 AKT1 E17K mutant phosphorylates GSK3 TAS Homo sapiens 30616 R-HSA-2399969 https://reactome.org/PathwayBrowser/#/R-HSA-2399969 AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1 TAS Homo sapiens 30616 R-HSA-2399977 https://reactome.org/PathwayBrowser/#/R-HSA-2399977 AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40) TAS Homo sapiens 30616 R-HSA-2399981 https://reactome.org/PathwayBrowser/#/R-HSA-2399981 AKT1 E17K mutant phosphorylates MDM2 TAS Homo sapiens 30616 R-HSA-2399982 https://reactome.org/PathwayBrowser/#/R-HSA-2399982 AKT1 E17K mutant phosphorylates TSC2, inhibiting it TAS Homo sapiens 30616 R-HSA-2399985 https://reactome.org/PathwayBrowser/#/R-HSA-2399985 AKT1 E17K mutant phosphorylates caspase-9 TAS Homo sapiens 30616 R-HSA-2399988 https://reactome.org/PathwayBrowser/#/R-HSA-2399988 AKT1 E17K mutant phosphorylates NR4A1 (NUR77) TAS Homo sapiens 30616 R-HSA-2399992 https://reactome.org/PathwayBrowser/#/R-HSA-2399992 AKT1 E17K mutant phosphorylates forkhead box transcription factors TAS Homo sapiens 30616 R-HSA-2399996 https://reactome.org/PathwayBrowser/#/R-HSA-2399996 AKT1 E17K mutant phosphorylates CREB1 TAS Homo sapiens 30616 R-HSA-2399999 https://reactome.org/PathwayBrowser/#/R-HSA-2399999 AKT1 E17K mutant phosphorylates RSK TAS Homo sapiens 30616 R-HSA-2400001 https://reactome.org/PathwayBrowser/#/R-HSA-2400001 AKT1 E17K mutant phosphorylates CHUK (IKKalpha) TAS Homo sapiens 30616 R-HSA-2404193 https://reactome.org/PathwayBrowser/#/R-HSA-2404193 IGF1R phosphorylates SHC1 TAS Homo sapiens 30616 R-HSA-2404199 https://reactome.org/PathwayBrowser/#/R-HSA-2404199 IGF1,2:IGF1R autophosphorylates TAS Homo sapiens 30616 R-HSA-2408507 https://reactome.org/PathwayBrowser/#/R-HSA-2408507 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK IEA Homo sapiens 30616 R-HSA-2408525 https://reactome.org/PathwayBrowser/#/R-HSA-2408525 H2SeO4 is converted to APSe by PAPSS1,2 IEA Homo sapiens 30616 R-HSA-2408526 https://reactome.org/PathwayBrowser/#/R-HSA-2408526 tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer TAS Homo sapiens 30616 R-HSA-2408540 https://reactome.org/PathwayBrowser/#/R-HSA-2408540 APSe is phosphorylated to PAPSe by PAPSS1,2 IEA Homo sapiens 30616 R-HSA-2408546 https://reactome.org/PathwayBrowser/#/R-HSA-2408546 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex IEA Homo sapiens 30616 R-HSA-2408551 https://reactome.org/PathwayBrowser/#/R-HSA-2408551 SeMet is converted to AdoSeMet by MAT TAS Homo sapiens 30616 R-HSA-2422927 https://reactome.org/PathwayBrowser/#/R-HSA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 TAS Homo sapiens 30616 R-HSA-2424480 https://reactome.org/PathwayBrowser/#/R-HSA-2424480 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-2424484 https://reactome.org/PathwayBrowser/#/R-HSA-2424484 Phosphorylation of BTK by p-SYK TAS Homo sapiens 30616 R-HSA-2424486 https://reactome.org/PathwayBrowser/#/R-HSA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK TAS Homo sapiens 30616 R-HSA-2424487 https://reactome.org/PathwayBrowser/#/R-HSA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK TAS Homo sapiens 30616 R-HSA-2428926 https://reactome.org/PathwayBrowser/#/R-HSA-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 TAS Homo sapiens 30616 R-HSA-2430533 https://reactome.org/PathwayBrowser/#/R-HSA-2430533 CDK1 phosphorylates MASTL IEA Homo sapiens 30616 R-HSA-2430535 https://reactome.org/PathwayBrowser/#/R-HSA-2430535 MASTL phosphorylates ENSA TAS Homo sapiens 30616 R-HSA-2454208 https://reactome.org/PathwayBrowser/#/R-HSA-2454208 Phosphorylation of beta and gamma subunits by LYN TAS Homo sapiens 30616 R-HSA-2454239 https://reactome.org/PathwayBrowser/#/R-HSA-2454239 Phosphorylation of SYK IEA Homo sapiens 30616 R-HSA-2466068 https://reactome.org/PathwayBrowser/#/R-HSA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms TAS Homo sapiens 30616 R-HSA-2466749 https://reactome.org/PathwayBrowser/#/R-HSA-2466749 ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol IEA Homo sapiens 30616 R-HSA-2466802 https://reactome.org/PathwayBrowser/#/R-HSA-2466802 Defective ABCA4 does not transport NRPE from disc membranes TAS Homo sapiens 30616 R-HSA-2468287 https://reactome.org/PathwayBrowser/#/R-HSA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres TAS Homo sapiens 30616 R-HSA-2468293 https://reactome.org/PathwayBrowser/#/R-HSA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms TAS Homo sapiens 30616 R-HSA-2470508 https://reactome.org/PathwayBrowser/#/R-HSA-2470508 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin IEA Homo sapiens 30616 R-HSA-2514854 https://reactome.org/PathwayBrowser/#/R-HSA-2514854 CDK1 phosphorylates condensin I IEA Homo sapiens 30616 R-HSA-2529020 https://reactome.org/PathwayBrowser/#/R-HSA-2529020 CK2 phosphorylates condensin I subunits TAS Homo sapiens 30616 R-HSA-2562526 https://reactome.org/PathwayBrowser/#/R-HSA-2562526 PLK1 phosphorylates OPTN TAS Homo sapiens 30616 R-HSA-2574840 https://reactome.org/PathwayBrowser/#/R-HSA-2574840 AJUBA facilitates AURKA autophosphorylation TAS Homo sapiens 30616 R-HSA-2581474 https://reactome.org/PathwayBrowser/#/R-HSA-2581474 GRK1,4,7 phosphorylate MII to p-MII TAS Homo sapiens 30616 R-HSA-2586553 https://reactome.org/PathwayBrowser/#/R-HSA-2586553 JAK2 Phosphorylates LEPR IEA Homo sapiens 30616 R-HSA-2586555 https://reactome.org/PathwayBrowser/#/R-HSA-2586555 JAK2 Autophosphorylates in Response to Leptin IEA Homo sapiens 30616 R-HSA-265682 https://reactome.org/PathwayBrowser/#/R-HSA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel TAS Homo sapiens 30616 R-HSA-265783 https://reactome.org/PathwayBrowser/#/R-HSA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-266082 https://reactome.org/PathwayBrowser/#/R-HSA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface TAS Homo sapiens 30616 R-HSA-2671742 https://reactome.org/PathwayBrowser/#/R-HSA-2671742 JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin IEA Homo sapiens 30616 R-HSA-2671829 https://reactome.org/PathwayBrowser/#/R-HSA-2671829 JAK2 Phosphorylates STAT5 in Response to Leptin IEA Homo sapiens 30616 R-HSA-2671850 https://reactome.org/PathwayBrowser/#/R-HSA-2671850 JAK2 Phosphoryates STAT3 in Response to Leptin IEA Homo sapiens 30616 R-HSA-2671862 https://reactome.org/PathwayBrowser/#/R-HSA-2671862 JAK2 Phosphorylates IRS in Response to Leptin IEA Homo sapiens 30616 R-HSA-2682349 https://reactome.org/PathwayBrowser/#/R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels TAS Homo sapiens 30616 R-HSA-2730833 https://reactome.org/PathwayBrowser/#/R-HSA-2730833 Phosphorylation of TEC kinases by p-SYK TAS Homo sapiens 30616 R-HSA-2730835 https://reactome.org/PathwayBrowser/#/R-HSA-2730835 Autophosphorylation of PKC-theta TAS Homo sapiens 30616 R-HSA-2730841 https://reactome.org/PathwayBrowser/#/R-HSA-2730841 Phosphorylation and activation of VAV TAS Homo sapiens 30616 R-HSA-2730843 https://reactome.org/PathwayBrowser/#/R-HSA-2730843 Phosphorylation of LAT by p-SYK TAS Homo sapiens 30616 R-HSA-2730851 https://reactome.org/PathwayBrowser/#/R-HSA-2730851 Phosphorylation of SLP-76 by p-SYK TAS Homo sapiens 30616 R-HSA-2730856 https://reactome.org/PathwayBrowser/#/R-HSA-2730856 Autophosphorylation of PAK TAS Homo sapiens 30616 R-HSA-2730858 https://reactome.org/PathwayBrowser/#/R-HSA-2730858 Autophosphorylation of BTK/ITK TAS Homo sapiens 30616 R-HSA-2730860 https://reactome.org/PathwayBrowser/#/R-HSA-2730860 Phosphorylation of GAB2 by SYK/FYN IEA Homo sapiens 30616 R-HSA-2730862 https://reactome.org/PathwayBrowser/#/R-HSA-2730862 Autophosphorylation of LYN kinase TAS Homo sapiens 30616 R-HSA-2730863 https://reactome.org/PathwayBrowser/#/R-HSA-2730863 Phosphorylation of CARMA1 by PKC-theta TAS Homo sapiens 30616 R-HSA-2730868 https://reactome.org/PathwayBrowser/#/R-HSA-2730868 Phosphorylation of MEK7 by MEKK1 TAS Homo sapiens 30616 R-HSA-2730870 https://reactome.org/PathwayBrowser/#/R-HSA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K TAS Homo sapiens 30616 R-HSA-2730876 https://reactome.org/PathwayBrowser/#/R-HSA-2730876 Phosphorylation of IKK-beta by TAK1 TAS Homo sapiens 30616 R-HSA-2730882 https://reactome.org/PathwayBrowser/#/R-HSA-2730882 Phosphorylation of PKC-theta TAS Homo sapiens 30616 R-HSA-2730884 https://reactome.org/PathwayBrowser/#/R-HSA-2730884 Phosphorylation of NTAL by p-SYK/Lyn TAS Homo sapiens 30616 R-HSA-2730886 https://reactome.org/PathwayBrowser/#/R-HSA-2730886 Phosphorylation of SHC by SYK kinase TAS Homo sapiens 30616 R-HSA-2730887 https://reactome.org/PathwayBrowser/#/R-HSA-2730887 Autophosphorylation and activation of MEKK1 IEA Homo sapiens 30616 R-HSA-2730888 https://reactome.org/PathwayBrowser/#/R-HSA-2730888 Phosphorylation of PLC-gamma IEA Homo sapiens 30616 R-HSA-2730896 https://reactome.org/PathwayBrowser/#/R-HSA-2730896 Phosphorylation of MEK4 by MEKK1 TAS Homo sapiens 30616 R-HSA-2730900 https://reactome.org/PathwayBrowser/#/R-HSA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 TAS Homo sapiens 30616 R-HSA-2730904 https://reactome.org/PathwayBrowser/#/R-HSA-2730904 Auto-ubiquitination of TRAF6 TAS Homo sapiens 30616 R-HSA-2855020 https://reactome.org/PathwayBrowser/#/R-HSA-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol TAS Homo sapiens 30616 R-HSA-2984220 https://reactome.org/PathwayBrowser/#/R-HSA-2984220 CDK1:CCNB phosphorylates NEK9 TAS Homo sapiens 30616 R-HSA-2984226 https://reactome.org/PathwayBrowser/#/R-HSA-2984226 PLK1 phosphorylates NEK9 TAS Homo sapiens 30616 R-HSA-2984258 https://reactome.org/PathwayBrowser/#/R-HSA-2984258 NEK9 phosphorylates NEK6/NEK7 TAS Homo sapiens 30616 R-HSA-2990833 https://reactome.org/PathwayBrowser/#/R-HSA-2990833 Conjugation of SUMO1 to UBA2:SAE1 TAS Homo sapiens 30616 R-HSA-2990880 https://reactome.org/PathwayBrowser/#/R-HSA-2990880 NEK6/NEK7 phosphorylates NUP98 TAS Homo sapiens 30616 R-HSA-2990882 https://reactome.org/PathwayBrowser/#/R-HSA-2990882 CDK1 phosphorylates NUP98 TAS Homo sapiens 30616 R-HSA-2993447 https://reactome.org/PathwayBrowser/#/R-HSA-2993447 HLCS biotinylates 6x(PCCA:PCCB) TAS Homo sapiens 30616 R-HSA-2993781 https://reactome.org/PathwayBrowser/#/R-HSA-2993781 Conjugation of SUMO3 to UBA2:SAE1 IEA Homo sapiens 30616 R-HSA-2993784 https://reactome.org/PathwayBrowser/#/R-HSA-2993784 Conjugation of SUMO2 to UBA2:SAE1 IEA Homo sapiens 30616 R-HSA-2993799 https://reactome.org/PathwayBrowser/#/R-HSA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 TAS Homo sapiens 30616 R-HSA-2993802 https://reactome.org/PathwayBrowser/#/R-HSA-2993802 HLCS biotinylates PC:Mn2+ TAS Homo sapiens 30616 R-HSA-2993814 https://reactome.org/PathwayBrowser/#/R-HSA-2993814 HLCS biotinylates ACACA:Mn2+ TAS Homo sapiens 30616 R-HSA-2993898 https://reactome.org/PathwayBrowser/#/R-HSA-2993898 VRK1/VRK2 phosphorylate BANF1 TAS Homo sapiens 30616 R-HSA-3000310 https://reactome.org/PathwayBrowser/#/R-HSA-3000310 AURKA phosphorylates PLK1 TAS Homo sapiens 30616 R-HSA-3000327 https://reactome.org/PathwayBrowser/#/R-HSA-3000327 PLK1 phosphorylates BORA TAS Homo sapiens 30616 R-HSA-3095901 https://reactome.org/PathwayBrowser/#/R-HSA-3095901 ABCC1 transports cytosolic RCbl to extracellular region TAS Homo sapiens 30616 R-HSA-3132737 https://reactome.org/PathwayBrowser/#/R-HSA-3132737 MAPKs phosphorylate ETS1 and ETS2 TAS Homo sapiens 30616 R-HSA-3134904 https://reactome.org/PathwayBrowser/#/R-HSA-3134904 Phosphorylation of beta-catenin at Ser552 TAS Homo sapiens 30616 R-HSA-3159253 https://reactome.org/PathwayBrowser/#/R-HSA-3159253 MMAB adenosylates cob(I)alamin TAS Homo sapiens 30616 R-HSA-3209160 https://reactome.org/PathwayBrowser/#/R-HSA-3209160 Activated ERKs phosphorylate ERF IEA Homo sapiens 30616 R-HSA-3215391 https://reactome.org/PathwayBrowser/#/R-HSA-3215391 PRMT5 is tyrosine phosphorylated by JAK2 V617F TAS Homo sapiens 30616 R-HSA-3222006 https://reactome.org/PathwayBrowser/#/R-HSA-3222006 STK11 (LKB1) phosphorylates NUAK1 TAS Homo sapiens 30616 R-HSA-3222020 https://reactome.org/PathwayBrowser/#/R-HSA-3222020 NUAK1 phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-3228469 https://reactome.org/PathwayBrowser/#/R-HSA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 TAS Homo sapiens 30616 R-HSA-3229102 https://reactome.org/PathwayBrowser/#/R-HSA-3229102 p-MAPKAPK3 phosphorylates BMI1 TAS Homo sapiens 30616 R-HSA-3229152 https://reactome.org/PathwayBrowser/#/R-HSA-3229152 MAP3K5 (ASK1) phosphorylates MAP2K4 (SEK1) IEA Homo sapiens 30616 R-HSA-3238999 https://reactome.org/PathwayBrowser/#/R-HSA-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 TAS Homo sapiens 30616 R-HSA-3239014 https://reactome.org/PathwayBrowser/#/R-HSA-3239014 MAPKAPK5 phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-3239019 https://reactome.org/PathwayBrowser/#/R-HSA-3239019 Active p38 MAPK phosphorylates MAPKAPK5 TAS Homo sapiens 30616 R-HSA-3244614 https://reactome.org/PathwayBrowser/#/R-HSA-3244614 cGAS produces cyclic GMP-AMP TAS Homo sapiens 30616 R-HSA-3249371 https://reactome.org/PathwayBrowser/#/R-HSA-3249371 TBK1 phosphorylates STAT6 at Ser407 TAS Homo sapiens 30616 R-HSA-3249379 https://reactome.org/PathwayBrowser/#/R-HSA-3249379 p-S407-STAT6 is phosphorylated at Tyr641 TAS Homo sapiens 30616 R-HSA-3249390 https://reactome.org/PathwayBrowser/#/R-HSA-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex TAS Homo sapiens 30616 R-HSA-3304394 https://reactome.org/PathwayBrowser/#/R-HSA-3304394 Activated TGFBR1 cannot phosphorylate SMAD2 and SMAD3 Phosphorylation Motif Mutants TAS Homo sapiens 30616 R-HSA-3322125 https://reactome.org/PathwayBrowser/#/R-HSA-3322125 Defective MMAB does not transfer adenosyl group from ATP to B12s TAS Homo sapiens 30616 R-HSA-3323184 https://reactome.org/PathwayBrowser/#/R-HSA-3323184 Defective HLCS does not biotinylate ACACA:Mn2+ TAS Homo sapiens 30616 R-HSA-3371422 https://reactome.org/PathwayBrowser/#/R-HSA-3371422 ATP hydrolysis by HSP70 TAS Homo sapiens 30616 R-HSA-3371435 https://reactome.org/PathwayBrowser/#/R-HSA-3371435 Constitutive phosphorylation by GSK3 TAS Homo sapiens 30616 R-HSA-3371531 https://reactome.org/PathwayBrowser/#/R-HSA-3371531 Constitutive phosphorylation by pERK1/2 TAS Homo sapiens 30616 R-HSA-3371567 https://reactome.org/PathwayBrowser/#/R-HSA-3371567 DBC1 is phosphorylated by ATM/ART TAS Homo sapiens 30616 R-HSA-3371590 https://reactome.org/PathwayBrowser/#/R-HSA-3371590 HSP70 binds to HSP40:nascent protein TAS Homo sapiens 30616 R-HSA-349426 https://reactome.org/PathwayBrowser/#/R-HSA-349426 Phosphorylation of MDM4 by CHEK2 TAS Homo sapiens 30616 R-HSA-349444 https://reactome.org/PathwayBrowser/#/R-HSA-349444 Phosphorylation of COP1 at Ser-387 by ATM TAS Homo sapiens 30616 R-HSA-349455 https://reactome.org/PathwayBrowser/#/R-HSA-349455 Phosphorylation of MDM4 by ATM TAS Homo sapiens 30616 R-HSA-349520 https://reactome.org/PathwayBrowser/#/R-HSA-349520 Re-acidification of acetylcholine transport vesicles TAS Homo sapiens 30616 R-HSA-354073 https://reactome.org/PathwayBrowser/#/R-HSA-354073 Autophosphorylation of PTK2 at Y397 TAS Homo sapiens 30616 R-HSA-354124 https://reactome.org/PathwayBrowser/#/R-HSA-354124 Phosphorylation of pPTK2 by SRC TAS Homo sapiens 30616 R-HSA-3560785 https://reactome.org/PathwayBrowser/#/R-HSA-3560785 Defective PAPSS2 does not transfer PO4(2-) group from ATP to APS to form PAPS TAS Homo sapiens 30616 R-HSA-3560794 https://reactome.org/PathwayBrowser/#/R-HSA-3560794 Defective PAPSS2 does not transfer SO4(2-) group to ATP to form APS TAS Homo sapiens 30616 R-HSA-3645780 https://reactome.org/PathwayBrowser/#/R-HSA-3645780 TGFBR2 KD mutants do not phosphorylate TGFBR1 TAS Homo sapiens 30616 R-HSA-3697838 https://reactome.org/PathwayBrowser/#/R-HSA-3697838 ATP7A transfers Cu from ATOX1 to SOD3 IEA Homo sapiens 30616 R-HSA-372693 https://reactome.org/PathwayBrowser/#/R-HSA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex TAS Homo sapiens 30616 R-HSA-373736 https://reactome.org/PathwayBrowser/#/R-HSA-373736 Shootin-1 links L1 and retrograde actin flow IEA Homo sapiens 30616 R-HSA-373739 https://reactome.org/PathwayBrowser/#/R-HSA-373739 Ankyrins link voltage-gated sodium and potassium channels to spectrin and L1 IEA Homo sapiens 30616 R-HSA-373747 https://reactome.org/PathwayBrowser/#/R-HSA-373747 Phosphorylation of nephrin by FYN TAS Homo sapiens 30616 R-HSA-373750 https://reactome.org/PathwayBrowser/#/R-HSA-373750 SEMA4D interacts with Plexin-B1:ErbB2 TAS Homo sapiens 30616 R-HSA-374664 https://reactome.org/PathwayBrowser/#/R-HSA-374664 Phosphorylation and activation of Ezrin TAS Homo sapiens 30616 R-HSA-374696 https://reactome.org/PathwayBrowser/#/R-HSA-374696 Phosphorylation of L1 by p90rsk IEA Homo sapiens 30616 R-HSA-374701 https://reactome.org/PathwayBrowser/#/R-HSA-374701 Phosphorylation of DCC by Fyn TAS Homo sapiens 30616 R-HSA-374916 https://reactome.org/PathwayBrowser/#/R-HSA-374916 Re-acidification of clathrin sculpted monoamine transport vesicle lumen TAS Homo sapiens 30616 R-HSA-375160 https://reactome.org/PathwayBrowser/#/R-HSA-375160 NCAM1 binds to ATP TAS Homo sapiens 30616 R-HSA-3769394 https://reactome.org/PathwayBrowser/#/R-HSA-3769394 AKT phosphorylates CBY1 TAS Homo sapiens 30616 R-HSA-377186 https://reactome.org/PathwayBrowser/#/R-HSA-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) TAS Homo sapiens 30616 R-HSA-3772435 https://reactome.org/PathwayBrowser/#/R-HSA-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL TAS Homo sapiens 30616 R-HSA-3772436 https://reactome.org/PathwayBrowser/#/R-HSA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 TAS Homo sapiens 30616 R-HSA-377640 https://reactome.org/PathwayBrowser/#/R-HSA-377640 Autophosphorylation of SRC TAS Homo sapiens 30616 R-HSA-3788705 https://reactome.org/PathwayBrowser/#/R-HSA-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 TAS Homo sapiens 30616 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 30616 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 30616 R-HSA-379844 https://reactome.org/PathwayBrowser/#/R-HSA-379844 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379848 https://reactome.org/PathwayBrowser/#/R-HSA-379848 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379861 https://reactome.org/PathwayBrowser/#/R-HSA-379861 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379864 https://reactome.org/PathwayBrowser/#/R-HSA-379864 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379865 https://reactome.org/PathwayBrowser/#/R-HSA-379865 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379867 https://reactome.org/PathwayBrowser/#/R-HSA-379867 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379887 https://reactome.org/PathwayBrowser/#/R-HSA-379887 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379893 https://reactome.org/PathwayBrowser/#/R-HSA-379893 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379974 https://reactome.org/PathwayBrowser/#/R-HSA-379974 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379977 https://reactome.org/PathwayBrowser/#/R-HSA-379977 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379980 https://reactome.org/PathwayBrowser/#/R-HSA-379980 tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379982 https://reactome.org/PathwayBrowser/#/R-HSA-379982 glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379992 https://reactome.org/PathwayBrowser/#/R-HSA-379992 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379993 https://reactome.org/PathwayBrowser/#/R-HSA-379993 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379994 https://reactome.org/PathwayBrowser/#/R-HSA-379994 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-379996 https://reactome.org/PathwayBrowser/#/R-HSA-379996 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380002 https://reactome.org/PathwayBrowser/#/R-HSA-380002 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380008 https://reactome.org/PathwayBrowser/#/R-HSA-380008 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380042 https://reactome.org/PathwayBrowser/#/R-HSA-380042 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380048 https://reactome.org/PathwayBrowser/#/R-HSA-380048 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380157 https://reactome.org/PathwayBrowser/#/R-HSA-380157 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380158 https://reactome.org/PathwayBrowser/#/R-HSA-380158 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate IEA Homo sapiens 30616 R-HSA-380170 https://reactome.org/PathwayBrowser/#/R-HSA-380170 tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380176 https://reactome.org/PathwayBrowser/#/R-HSA-380176 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380177 https://reactome.org/PathwayBrowser/#/R-HSA-380177 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate IEA Homo sapiens 30616 R-HSA-380198 https://reactome.org/PathwayBrowser/#/R-HSA-380198 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate IEA Homo sapiens 30616 R-HSA-380199 https://reactome.org/PathwayBrowser/#/R-HSA-380199 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate IEA Homo sapiens 30616 R-HSA-380200 https://reactome.org/PathwayBrowser/#/R-HSA-380200 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380201 https://reactome.org/PathwayBrowser/#/R-HSA-380201 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate IEA Homo sapiens 30616 R-HSA-380203 https://reactome.org/PathwayBrowser/#/R-HSA-380203 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380216 https://reactome.org/PathwayBrowser/#/R-HSA-380216 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate IEA Homo sapiens 30616 R-HSA-380222 https://reactome.org/PathwayBrowser/#/R-HSA-380222 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380224 https://reactome.org/PathwayBrowser/#/R-HSA-380224 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380227 https://reactome.org/PathwayBrowser/#/R-HSA-380227 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate IEA Homo sapiens 30616 R-HSA-380229 https://reactome.org/PathwayBrowser/#/R-HSA-380229 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380233 https://reactome.org/PathwayBrowser/#/R-HSA-380233 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380234 https://reactome.org/PathwayBrowser/#/R-HSA-380234 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380239 https://reactome.org/PathwayBrowser/#/R-HSA-380239 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380240 https://reactome.org/PathwayBrowser/#/R-HSA-380240 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380241 https://reactome.org/PathwayBrowser/#/R-HSA-380241 glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-380272 https://reactome.org/PathwayBrowser/#/R-HSA-380272 Plk1-mediated phosphorylation of Nlp TAS Homo sapiens 30616 R-HSA-380278 https://reactome.org/PathwayBrowser/#/R-HSA-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 TAS Homo sapiens 30616 R-HSA-380780 https://reactome.org/PathwayBrowser/#/R-HSA-380780 Activation of Src TAS Homo sapiens 30616 R-HSA-380927 https://reactome.org/PathwayBrowser/#/R-HSA-380927 p-AMPK phosphorylates TSC1:TSC2 TAS Homo sapiens 30616 R-HSA-381091 https://reactome.org/PathwayBrowser/#/R-HSA-381091 IRE1 dimer autophosphorylates TAS Homo sapiens 30616 R-HSA-381111 https://reactome.org/PathwayBrowser/#/R-HSA-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK TAS Homo sapiens 30616 R-HSA-381607 https://reactome.org/PathwayBrowser/#/R-HSA-381607 Activated Adenylyl cyclase synthesizes cyclic AMP TAS Homo sapiens 30616 R-HSA-382553 https://reactome.org/PathwayBrowser/#/R-HSA-382553 ABCA7:Apo1A-mediated phospholipid efflux TAS Homo sapiens 30616 R-HSA-382560 https://reactome.org/PathwayBrowser/#/R-HSA-382560 ABC7, mABC1 and mABC2 mediate heme transport TAS Homo sapiens 30616 R-HSA-382575 https://reactome.org/PathwayBrowser/#/R-HSA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix TAS Homo sapiens 30616 R-HSA-383190 https://reactome.org/PathwayBrowser/#/R-HSA-383190 HCO3- transport through ion channel TAS Homo sapiens 30616 R-HSA-3857328 https://reactome.org/PathwayBrowser/#/R-HSA-3857328 RPS6KA1/2/3 phosphorylates CEBPB on S321 IEA Homo sapiens 30616 R-HSA-3857329 https://reactome.org/PathwayBrowser/#/R-HSA-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB TAS Homo sapiens 30616 R-HSA-3858480 https://reactome.org/PathwayBrowser/#/R-HSA-3858480 WNT-dependent phosphorylation of DVL IEA Homo sapiens 30616 R-HSA-388831 https://reactome.org/PathwayBrowser/#/R-HSA-388831 Phosphorylation of CD28 TAS Homo sapiens 30616 R-HSA-388833 https://reactome.org/PathwayBrowser/#/R-HSA-388833 Phosphorylation of CTLA-4 TAS Homo sapiens 30616 R-HSA-389083 https://reactome.org/PathwayBrowser/#/R-HSA-389083 Autophosphorylation of PDGF alpha receptors TAS Homo sapiens 30616 R-HSA-389086 https://reactome.org/PathwayBrowser/#/R-HSA-389086 Autophosphorylation of PDGF alpha/beta receptors TAS Homo sapiens 30616 R-HSA-389158 https://reactome.org/PathwayBrowser/#/R-HSA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-389159 https://reactome.org/PathwayBrowser/#/R-HSA-389159 CSF1R trans-autophosphorylates on multiple tyrosine and serine residues IEA Homo sapiens 30616 R-HSA-389354 https://reactome.org/PathwayBrowser/#/R-HSA-389354 Activation of Vav1 TAS Homo sapiens 30616 R-HSA-389622 https://reactome.org/PathwayBrowser/#/R-HSA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-389632 https://reactome.org/PathwayBrowser/#/R-HSA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-389652 https://reactome.org/PathwayBrowser/#/R-HSA-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP TAS Homo sapiens 30616 R-HSA-389756 https://reactome.org/PathwayBrowser/#/R-HSA-389756 AKT interacts and phosphorylates Cot TAS Homo sapiens 30616 R-HSA-389762 https://reactome.org/PathwayBrowser/#/R-HSA-389762 Phosphorylation of PD-1 TAS Homo sapiens 30616 R-HSA-389954 https://reactome.org/PathwayBrowser/#/R-HSA-389954 Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC IEA Homo sapiens 30616 R-HSA-389961 https://reactome.org/PathwayBrowser/#/R-HSA-389961 ADP is exchanged for ATP in the (ADP:CCT/TriC):tubulin complex IEA Homo sapiens 30616 R-HSA-390453 https://reactome.org/PathwayBrowser/#/R-HSA-390453 Hydrolysis of ATP and release of folded actin from CCT/TriC IEA Homo sapiens 30616 R-HSA-390459 https://reactome.org/PathwayBrowser/#/R-HSA-390459 Exchange of ADP for ATP in CCT/TriC:actin complex IEA Homo sapiens 30616 R-HSA-390593 https://reactome.org/PathwayBrowser/#/R-HSA-390593 ATP Hydrolysis By Myosin TAS Homo sapiens 30616 R-HSA-390598 https://reactome.org/PathwayBrowser/#/R-HSA-390598 Myosin Binds ATP TAS Homo sapiens 30616 R-HSA-391156 https://reactome.org/PathwayBrowser/#/R-HSA-391156 Phosphorylation of ITIM motif in SIRP alpha IEA Homo sapiens 30616 R-HSA-391865 https://reactome.org/PathwayBrowser/#/R-HSA-391865 Recruitment of FAK to NCAM1:Fyn in lipid rafts IEA Homo sapiens 30616 R-HSA-391866 https://reactome.org/PathwayBrowser/#/R-HSA-391866 Phosphorylation of FAK by Src kinase IEA Homo sapiens 30616 R-HSA-391871 https://reactome.org/PathwayBrowser/#/R-HSA-391871 Autophosphorylation of NCAM1 bound Fyn IEA Homo sapiens 30616 R-HSA-392129 https://reactome.org/PathwayBrowser/#/R-HSA-392129 Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate IEA Homo sapiens 30616 R-HSA-392300 https://reactome.org/PathwayBrowser/#/R-HSA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-392530 https://reactome.org/PathwayBrowser/#/R-HSA-392530 p-S400-Cot phosphorylates NIK TAS Homo sapiens 30616 R-HSA-392751 https://reactome.org/PathwayBrowser/#/R-HSA-392751 L1 linked to actin cytoskeleton by ankyrin TAS Homo sapiens 30616 R-HSA-392752 https://reactome.org/PathwayBrowser/#/R-HSA-392752 Phosphorylation of L1 by CK-II TAS Homo sapiens 30616 R-HSA-3928577 https://reactome.org/PathwayBrowser/#/R-HSA-3928577 ROCK phosphorylates LIMK1,2 IEA Homo sapiens 30616 R-HSA-3928578 https://reactome.org/PathwayBrowser/#/R-HSA-3928578 EPH receptors autophosphorylate TAS Homo sapiens 30616 R-HSA-3928580 https://reactome.org/PathwayBrowser/#/R-HSA-3928580 SFKs phosphorylate EFNBs IEA Homo sapiens 30616 R-HSA-3928583 https://reactome.org/PathwayBrowser/#/R-HSA-3928583 FYN phosphorylates NMDAR2B IEA Homo sapiens 30616 R-HSA-3928594 https://reactome.org/PathwayBrowser/#/R-HSA-3928594 SFKs phosphorylate GIT1 IEA Homo sapiens 30616 R-HSA-3928595 https://reactome.org/PathwayBrowser/#/R-HSA-3928595 N-WASP binds ARP2/3 and G-actin TAS Homo sapiens 30616 R-HSA-3928604 https://reactome.org/PathwayBrowser/#/R-HSA-3928604 SFKs phosphorylate VAV2,3 TAS Homo sapiens 30616 R-HSA-3928608 https://reactome.org/PathwayBrowser/#/R-HSA-3928608 LIMK phosphorylates CFL1, inactivating it IEA Homo sapiens 30616 R-HSA-3928610 https://reactome.org/PathwayBrowser/#/R-HSA-3928610 PTK2 autophosphorylates at Y397 IEA Homo sapiens 30616 R-HSA-3928616 https://reactome.org/PathwayBrowser/#/R-HSA-3928616 Activated ROCK phosphorylates MRLCs IEA Homo sapiens 30616 R-HSA-3928620 https://reactome.org/PathwayBrowser/#/R-HSA-3928620 PAK1 autophosphorylates TAS Homo sapiens 30616 R-HSA-3928625 https://reactome.org/PathwayBrowser/#/R-HSA-3928625 PAKs autophosphorylate TAS Homo sapiens 30616 R-HSA-3928627 https://reactome.org/PathwayBrowser/#/R-HSA-3928627 EPHB phosphorylates TIAM1 TAS Homo sapiens 30616 R-HSA-3928640 https://reactome.org/PathwayBrowser/#/R-HSA-3928640 PAKs phosphorylate MLC TAS Homo sapiens 30616 R-HSA-3928648 https://reactome.org/PathwayBrowser/#/R-HSA-3928648 SFKs phosphorylate NGEF IEA Homo sapiens 30616 R-HSA-3928654 https://reactome.org/PathwayBrowser/#/R-HSA-3928654 Clathrin internalises EPH:EFN complexes TAS Homo sapiens 30616 R-HSA-399934 https://reactome.org/PathwayBrowser/#/R-HSA-399934 Phosphorylation of Plexin-A IEA Homo sapiens 30616 R-HSA-399939 https://reactome.org/PathwayBrowser/#/R-HSA-399939 Autophosphorylation of PAK TAS Homo sapiens 30616 R-HSA-399944 https://reactome.org/PathwayBrowser/#/R-HSA-399944 Phosphorylation of CRMPs by Cdk5 TAS Homo sapiens 30616 R-HSA-399946 https://reactome.org/PathwayBrowser/#/R-HSA-399946 Recruitment and activation of Cdk5 IEA Homo sapiens 30616 R-HSA-399947 https://reactome.org/PathwayBrowser/#/R-HSA-399947 Tyrosine phosphorylation of CRMPs by Fes TAS Homo sapiens 30616 R-HSA-399950 https://reactome.org/PathwayBrowser/#/R-HSA-399950 Phosphorylation of cofilin by LIMK-1 IEA Homo sapiens 30616 R-HSA-399951 https://reactome.org/PathwayBrowser/#/R-HSA-399951 Phosphorylation of CRMPs by GSK3beta TAS Homo sapiens 30616 R-HSA-399952 https://reactome.org/PathwayBrowser/#/R-HSA-399952 Phosphorylation of LIMK-1 by PAK TAS Homo sapiens 30616 R-HSA-399978 https://reactome.org/PathwayBrowser/#/R-HSA-399978 Protein kinase C, alpha type phosphorylates MARCKS TAS Homo sapiens 30616 R-HSA-400382 https://reactome.org/PathwayBrowser/#/R-HSA-400382 CSNK1E,CSNK1D phosphorylate CRY and PER proteins IEA Homo sapiens 30616 R-HSA-4085028 https://reactome.org/PathwayBrowser/#/R-HSA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P TAS Homo sapiens 30616 R-HSA-4086410 https://reactome.org/PathwayBrowser/#/R-HSA-4086410 CDK1 phosphorylates BORA TAS Homo sapiens 30616 R-HSA-4088024 https://reactome.org/PathwayBrowser/#/R-HSA-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 TAS Homo sapiens 30616 R-HSA-4088134 https://reactome.org/PathwayBrowser/#/R-HSA-4088134 PLK1 phosphorylates FOXM1 TAS Homo sapiens 30616 R-HSA-4088322 https://reactome.org/PathwayBrowser/#/R-HSA-4088322 Defective GNE does not phosphorylate ManNAc to ManNAc-6-P TAS Homo sapiens 30616 R-HSA-4093332 https://reactome.org/PathwayBrowser/#/R-HSA-4093332 p-EPHB phosphorylates SDC2 TAS Homo sapiens 30616 R-HSA-416320 https://reactome.org/PathwayBrowser/#/R-HSA-416320 Trafficking of GluR1-containing AMPA receptors TAS Homo sapiens 30616 R-HSA-416639 https://reactome.org/PathwayBrowser/#/R-HSA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites TAS Homo sapiens 30616 R-HSA-4167511 https://reactome.org/PathwayBrowser/#/R-HSA-4167511 HLCS biotinylates ACACB TAS Homo sapiens 30616 R-HSA-416985 https://reactome.org/PathwayBrowser/#/R-HSA-416985 Trafficking of GluR2-containing AMPA receptors to synapse TAS Homo sapiens 30616 R-HSA-417825 https://reactome.org/PathwayBrowser/#/R-HSA-417825 P2Y11 receptor can bind to ATP TAS Homo sapiens 30616 R-HSA-417927 https://reactome.org/PathwayBrowser/#/R-HSA-417927 P2Y2 receptor binds ATP and UTP TAS Homo sapiens 30616 R-HSA-418845 https://reactome.org/PathwayBrowser/#/R-HSA-418845 Activation of caspase-3 TAS Homo sapiens 30616 R-HSA-418859 https://reactome.org/PathwayBrowser/#/R-HSA-418859 Phosphorylation of Unc5C IEA Homo sapiens 30616 R-HSA-418872 https://reactome.org/PathwayBrowser/#/R-HSA-418872 Phosphorylation of FADK1 IEA Homo sapiens 30616 R-HSA-419033 https://reactome.org/PathwayBrowser/#/R-HSA-419033 NCAM1 binds FGFR-1 IEA Homo sapiens 30616 R-HSA-419083 https://reactome.org/PathwayBrowser/#/R-HSA-419083 Myosin phosphatase inactivation by ROCK IEA Homo sapiens 30616 R-HSA-419087 https://reactome.org/PathwayBrowser/#/R-HSA-419087 LIM kinase phosphorylation by ROCK IEA Homo sapiens 30616 R-HSA-419197 https://reactome.org/PathwayBrowser/#/R-HSA-419197 Myosin regulatory light chain phosphorylation by ROCK IEA Homo sapiens 30616 R-HSA-419490 https://reactome.org/PathwayBrowser/#/R-HSA-419490 Binding of ATP to P2X receptors TAS Homo sapiens 30616 R-HSA-419644 https://reactome.org/PathwayBrowser/#/R-HSA-419644 Transphosphorylation of pLIMK1 TAS Homo sapiens 30616 R-HSA-419646 https://reactome.org/PathwayBrowser/#/R-HSA-419646 SEMA4D interacts with Plexin-B1:Met TAS Homo sapiens 30616 R-HSA-421007 https://reactome.org/PathwayBrowser/#/R-HSA-421007 Endocytosis of Ca impermeable AMPA receptors TAS Homo sapiens 30616 R-HSA-421836 https://reactome.org/PathwayBrowser/#/R-HSA-421836 trans-Golgi Network Derived Vesicle Uncoating TAS Homo sapiens 30616 R-HSA-426240 https://reactome.org/PathwayBrowser/#/R-HSA-426240 DAG kinase produces phosphatidic acid from DAG TAS Homo sapiens 30616 R-HSA-428273 https://reactome.org/PathwayBrowser/#/R-HSA-428273 SPHK1 phosphorylates sphingoid TAS Homo sapiens 30616 R-HSA-428888 https://reactome.org/PathwayBrowser/#/R-HSA-428888 Phosphorylation of ROBO1 by ABL kinase TAS Homo sapiens 30616 R-HSA-428941 https://reactome.org/PathwayBrowser/#/R-HSA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha TAS Homo sapiens 30616 R-HSA-428961 https://reactome.org/PathwayBrowser/#/R-HSA-428961 Phosphorylation of cPLA2 by MAPK p38 alpha TAS Homo sapiens 30616 R-HSA-429016 https://reactome.org/PathwayBrowser/#/R-HSA-429016 ALOX5 is phosphorylated by MAPKAP2 TAS Homo sapiens 30616 R-HSA-429157 https://reactome.org/PathwayBrowser/#/R-HSA-429157 ABCC4 accumulation of dense granule contents TAS Homo sapiens 30616 R-HSA-429441 https://reactome.org/PathwayBrowser/#/R-HSA-429441 SYK activation by SRC TAS Homo sapiens 30616 R-HSA-429449 https://reactome.org/PathwayBrowser/#/R-HSA-429449 Syk activation leads to SLP-76 activation TAS Homo sapiens 30616 R-HSA-429698 https://reactome.org/PathwayBrowser/#/R-HSA-429698 PRKD1,2,3 phosphorylates CERT1-2 TAS Homo sapiens 30616 R-HSA-429714 https://reactome.org/PathwayBrowser/#/R-HSA-429714 CSNK1G2 phosphorylates p-CERT1-2 TAS Homo sapiens 30616 R-HSA-430347 https://reactome.org/PathwayBrowser/#/R-HSA-430347 MigFilin associates with Filamin and F-actin TAS Homo sapiens 30616 R-HSA-432129 https://reactome.org/PathwayBrowser/#/R-HSA-432129 FGR binds and phosphorylates LRP8 TAS Homo sapiens 30616 R-HSA-432148 https://reactome.org/PathwayBrowser/#/R-HSA-432148 Fgr may phosphorylate p38 MAPK TAS Homo sapiens 30616 R-HSA-432232 https://reactome.org/PathwayBrowser/#/R-HSA-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) TAS Homo sapiens 30616 R-HSA-432688 https://reactome.org/PathwayBrowser/#/R-HSA-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating TAS Homo sapiens 30616 R-HSA-4332358 https://reactome.org/PathwayBrowser/#/R-HSA-4332358 Dissociation of CaM and CAMK2 autophosphorylation TAS Homo sapiens 30616 R-HSA-4332363 https://reactome.org/PathwayBrowser/#/R-HSA-4332363 Autophosphorylation and activation of CAMK2 TAS Homo sapiens 30616 R-HSA-4332388 https://reactome.org/PathwayBrowser/#/R-HSA-4332388 Activation of MAP3K7 in response to WNT TAS Homo sapiens 30616 R-HSA-433725 https://reactome.org/PathwayBrowser/#/R-HSA-433725 Interaction of Afadin with F-actin IEA Homo sapiens 30616 R-HSA-434382 https://reactome.org/PathwayBrowser/#/R-HSA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell TAS Homo sapiens 30616 R-HSA-434836 https://reactome.org/PathwayBrowser/#/R-HSA-434836 Syk/Lck phosphorylate LAT TAS Homo sapiens 30616 R-HSA-435244 https://reactome.org/PathwayBrowser/#/R-HSA-435244 PECAM1 is phosphorylated TAS Homo sapiens 30616 R-HSA-437162 https://reactome.org/PathwayBrowser/#/R-HSA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-437195 https://reactome.org/PathwayBrowser/#/R-HSA-437195 PDPK1 activates PRKCZ IEA Homo sapiens 30616 R-HSA-437936 https://reactome.org/PathwayBrowser/#/R-HSA-437936 p-Y348-SYK phosphorylates VAV family IEA Homo sapiens 30616 R-HSA-4411383 https://reactome.org/PathwayBrowser/#/R-HSA-4411383 NLK phosphorylates TCF/LEF TAS Homo sapiens 30616 R-HSA-4411402 https://reactome.org/PathwayBrowser/#/R-HSA-4411402 Activation of NLK TAS Homo sapiens 30616 R-HSA-4420117 https://reactome.org/PathwayBrowser/#/R-HSA-4420117 VEGFR2 autophosphorylates TAS Homo sapiens 30616 R-HSA-4420121 https://reactome.org/PathwayBrowser/#/R-HSA-4420121 SFKs phosphorylate PLCG1 TAS Homo sapiens 30616 R-HSA-4420128 https://reactome.org/PathwayBrowser/#/R-HSA-4420128 SRC-1 phosphorylates SHB TAS Homo sapiens 30616 R-HSA-4420206 https://reactome.org/PathwayBrowser/#/R-HSA-4420206 Phosphorylation of SRC-1 TAS Homo sapiens 30616 R-HSA-442592 https://reactome.org/PathwayBrowser/#/R-HSA-442592 WASPs or WAVEs activate the ARP2/3 complex IEA Homo sapiens 30616 R-HSA-442715 https://reactome.org/PathwayBrowser/#/R-HSA-442715 Calmodulin-activated adenylate cyclases ADCY1 and ADCY8 generate cAMP IEA Homo sapiens 30616 R-HSA-442724 https://reactome.org/PathwayBrowser/#/R-HSA-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) TAS Homo sapiens 30616 R-HSA-442739 https://reactome.org/PathwayBrowser/#/R-HSA-442739 PDPK1 phosphorylates RSKs IEA Homo sapiens 30616 R-HSA-442749 https://reactome.org/PathwayBrowser/#/R-HSA-442749 CaMKK autophosphorylates in the nucleus TAS Homo sapiens 30616 R-HSA-442832 https://reactome.org/PathwayBrowser/#/R-HSA-442832 PAK phosphorylates cortactin IEA Homo sapiens 30616 R-HSA-443779 https://reactome.org/PathwayBrowser/#/R-HSA-443779 Linkage of L1 with treadmilling F-actin TAS Homo sapiens 30616 R-HSA-443817 https://reactome.org/PathwayBrowser/#/R-HSA-443817 Phosphorylation of L1 by EPHB2 IEA Homo sapiens 30616 R-HSA-445072 https://reactome.org/PathwayBrowser/#/R-HSA-445072 Interaction of PAK1 with Rac1-GTP TAS Homo sapiens 30616 R-HSA-445076 https://reactome.org/PathwayBrowser/#/R-HSA-445076 Phosphorylation of Y1229 in L1 TAS Homo sapiens 30616 R-HSA-445079 https://reactome.org/PathwayBrowser/#/R-HSA-445079 Phosphorylation of L1 by ERK TAS Homo sapiens 30616 R-HSA-445084 https://reactome.org/PathwayBrowser/#/R-HSA-445084 Phosphorylation of L1 by SRC TAS Homo sapiens 30616 R-HSA-445085 https://reactome.org/PathwayBrowser/#/R-HSA-445085 Phosphorylation of VAV2 TAS Homo sapiens 30616 R-HSA-445089 https://reactome.org/PathwayBrowser/#/R-HSA-445089 Dephosphorylation of pL1 (Y1176) TAS Homo sapiens 30616 R-HSA-445091 https://reactome.org/PathwayBrowser/#/R-HSA-445091 Phosphorylation of Neurofascin IEA Homo sapiens 30616 R-HSA-445699 https://reactome.org/PathwayBrowser/#/R-HSA-445699 ATP Hydrolysis By Myosin TAS Homo sapiens 30616 R-HSA-445700 https://reactome.org/PathwayBrowser/#/R-HSA-445700 Myosin Binds ATP TAS Homo sapiens 30616 R-HSA-445813 https://reactome.org/PathwayBrowser/#/R-HSA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains TAS Homo sapiens 30616 R-HSA-446634 https://reactome.org/PathwayBrowser/#/R-HSA-446634 IRAK4 is activated by autophosphorylation TAS Homo sapiens 30616 R-HSA-446694 https://reactome.org/PathwayBrowser/#/R-HSA-446694 IRAK4 phosphorylates IRAK1 TAS Homo sapiens 30616 R-HSA-446701 https://reactome.org/PathwayBrowser/#/R-HSA-446701 IRAK4-activated IRAK1 autophosphorylates TAS Homo sapiens 30616 R-HSA-447074 https://reactome.org/PathwayBrowser/#/R-HSA-447074 AMPK phosphorylates Raptor in the mTORC1 complex TAS Homo sapiens 30616 R-HSA-448948 https://reactome.org/PathwayBrowser/#/R-HSA-448948 Phosphorylation of E proteins by p38 MAPK IEA Homo sapiens 30616 R-HSA-448951 https://reactome.org/PathwayBrowser/#/R-HSA-448951 Activation of p38 alpha/beta MAPK IEA Homo sapiens 30616 R-HSA-448955 https://reactome.org/PathwayBrowser/#/R-HSA-448955 Phosphorylation of MEF2 proteins by p38 TAS Homo sapiens 30616 R-HSA-449911 https://reactome.org/PathwayBrowser/#/R-HSA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] TAS Homo sapiens 30616 R-HSA-450088 https://reactome.org/PathwayBrowser/#/R-HSA-450088 GLUT1 tetramer binds 4xATP TAS Homo sapiens 30616 R-HSA-450092 https://reactome.org/PathwayBrowser/#/R-HSA-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP TAS Homo sapiens 30616 R-HSA-450222 https://reactome.org/PathwayBrowser/#/R-HSA-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 TAS Homo sapiens 30616 R-HSA-450325 https://reactome.org/PathwayBrowser/#/R-HSA-450325 c-FOS activation by phospho ERK1/2 TAS Homo sapiens 30616 R-HSA-450333 https://reactome.org/PathwayBrowser/#/R-HSA-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 TAS Homo sapiens 30616 R-HSA-450337 https://reactome.org/PathwayBrowser/#/R-HSA-450337 Activated TAK1 phosphorylates MKK4/MKK7 TAS Homo sapiens 30616 R-HSA-450346 https://reactome.org/PathwayBrowser/#/R-HSA-450346 activated human TAK1 phosphorylates MKK3/MKK6 TAS Homo sapiens 30616 R-HSA-450463 https://reactome.org/PathwayBrowser/#/R-HSA-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) TAS Homo sapiens 30616 R-HSA-450474 https://reactome.org/PathwayBrowser/#/R-HSA-450474 MK2 phosphorylates BRF1 TAS Homo sapiens 30616 R-HSA-450490 https://reactome.org/PathwayBrowser/#/R-HSA-450490 Protein Kinase B/Akt phosphorylates BRF1 TAS Homo sapiens 30616 R-HSA-450499 https://reactome.org/PathwayBrowser/#/R-HSA-450499 Protein Kinase B (AKT) phosphorylates KSRP TAS Homo sapiens 30616 R-HSA-450533 https://reactome.org/PathwayBrowser/#/R-HSA-450533 PKCdelta phosphorylates HuR TAS Homo sapiens 30616 R-HSA-450550 https://reactome.org/PathwayBrowser/#/R-HSA-450550 PKCalpha phosphorylates HuR TAS Homo sapiens 30616 R-HSA-450827 https://reactome.org/PathwayBrowser/#/R-HSA-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. TAS Homo sapiens 30616 R-HSA-451152 https://reactome.org/PathwayBrowser/#/R-HSA-451152 MAP kinase p38 phosphorylates KSRP IEA Homo sapiens 30616 R-HSA-451649 https://reactome.org/PathwayBrowser/#/R-HSA-451649 TPL2 phosphorylates MEK1, SEK1 IEA Homo sapiens 30616 R-HSA-451942 https://reactome.org/PathwayBrowser/#/R-HSA-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 TAS Homo sapiens 30616 R-HSA-452097 https://reactome.org/PathwayBrowser/#/R-HSA-452097 Recruited STAT5 is phosphorylated TAS Homo sapiens 30616 R-HSA-452100 https://reactome.org/PathwayBrowser/#/R-HSA-452100 SHC1 bound to IL2 receptor is phosphorylated TAS Homo sapiens 30616 R-HSA-452122 https://reactome.org/PathwayBrowser/#/R-HSA-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB TAS Homo sapiens 30616 R-HSA-453200 https://reactome.org/PathwayBrowser/#/R-HSA-453200 SYK autophosphorylates TAS Homo sapiens 30616 R-HSA-453337 https://reactome.org/PathwayBrowser/#/R-HSA-453337 glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP IEA Homo sapiens 30616 R-HSA-453342 https://reactome.org/PathwayBrowser/#/R-HSA-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex TAS Homo sapiens 30616 R-HSA-4551570 https://reactome.org/PathwayBrowser/#/R-HSA-4551570 VANGL2 is phosphorylated in response to WNT5A IEA Homo sapiens 30616 R-HSA-4608825 https://reactome.org/PathwayBrowser/#/R-HSA-4608825 DVL2 is phosphorylated after WNT5A binding to FZD TAS Homo sapiens 30616 R-HSA-4793911 https://reactome.org/PathwayBrowser/#/R-HSA-4793911 MAPKAPK2 phosphorylates HSF1 TAS Homo sapiens 30616 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 30616 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 30616 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 30616 R-HSA-4827388 https://reactome.org/PathwayBrowser/#/R-HSA-4827388 CTNNB1 S45 mutants aren't phosphorylated by CK1alpha TAS Homo sapiens 30616 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 30616 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 30616 R-HSA-4839634 https://reactome.org/PathwayBrowser/#/R-HSA-4839634 CTNNB1 S33 mutants aren't phosphorylated by GSK3beta TAS Homo sapiens 30616 R-HSA-4839635 https://reactome.org/PathwayBrowser/#/R-HSA-4839635 CTNNB1 S37 mutants aren't phosphorylated by GSK3beta TAS Homo sapiens 30616 R-HSA-4839638 https://reactome.org/PathwayBrowser/#/R-HSA-4839638 CTNNB1 T41 mutants aren't phosphorylated by GSK3beta TAS Homo sapiens 30616 R-HSA-504054 https://reactome.org/PathwayBrowser/#/R-HSA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] TAS Homo sapiens 30616 R-HSA-508040 https://reactome.org/PathwayBrowser/#/R-HSA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] TAS Homo sapiens 30616 R-HSA-5082387 https://reactome.org/PathwayBrowser/#/R-HSA-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation TAS Homo sapiens 30616 R-HSA-5082405 https://reactome.org/PathwayBrowser/#/R-HSA-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation TAS Homo sapiens 30616 R-HSA-508282 https://reactome.org/PathwayBrowser/#/R-HSA-508282 SYK is a substrate for JAK1 TAS Homo sapiens 30616 R-HSA-508308 https://reactome.org/PathwayBrowser/#/R-HSA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] TAS Homo sapiens 30616 R-HSA-5138432 https://reactome.org/PathwayBrowser/#/R-HSA-5138432 DVL2 is phosphorylated by PKC TAS Homo sapiens 30616 R-HSA-5195402 https://reactome.org/PathwayBrowser/#/R-HSA-5195402 CDK1 phosphorylates LPIN TAS Homo sapiens 30616 R-HSA-5211224 https://reactome.org/PathwayBrowser/#/R-HSA-5211224 Anthrax cya catalyzes the conversion of ATP to cAMP TAS Homo sapiens 30616 R-HSA-5213464 https://reactome.org/PathwayBrowser/#/R-HSA-5213464 RIPK1 is phosphorylated TAS Homo sapiens 30616 R-HSA-5213466 https://reactome.org/PathwayBrowser/#/R-HSA-5213466 RIPK3 is phosphorylated TAS Homo sapiens 30616 R-HSA-5218640 https://reactome.org/PathwayBrowser/#/R-HSA-5218640 SRC-1 phosphorylates p-Y397-PTK2 TAS Homo sapiens 30616 R-HSA-5218642 https://reactome.org/PathwayBrowser/#/R-HSA-5218642 PTK2 autophosphorylates TAS Homo sapiens 30616 R-HSA-5218804 https://reactome.org/PathwayBrowser/#/R-HSA-5218804 p38 MAPK activation by VEGFR TAS Homo sapiens 30616 R-HSA-5218805 https://reactome.org/PathwayBrowser/#/R-HSA-5218805 PKC autophosphorylates TAS Homo sapiens 30616 R-HSA-5218806 https://reactome.org/PathwayBrowser/#/R-HSA-5218806 FYN autophosphorylates TAS Homo sapiens 30616 R-HSA-5218809 https://reactome.org/PathwayBrowser/#/R-HSA-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 TAS Homo sapiens 30616 R-HSA-5218812 https://reactome.org/PathwayBrowser/#/R-HSA-5218812 FYN phosphorylates PAK2 TAS Homo sapiens 30616 R-HSA-5218814 https://reactome.org/PathwayBrowser/#/R-HSA-5218814 PAK2 autophorylates TAS Homo sapiens 30616 R-HSA-5218819 https://reactome.org/PathwayBrowser/#/R-HSA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5218820 https://reactome.org/PathwayBrowser/#/R-HSA-5218820 Src kinases phosphorylate VAV TAS Homo sapiens 30616 R-HSA-5218821 https://reactome.org/PathwayBrowser/#/R-HSA-5218821 PDK1 phosphorylates PKC TAS Homo sapiens 30616 R-HSA-5218823 https://reactome.org/PathwayBrowser/#/R-HSA-5218823 PKC phosphorylates sphingosine kinase 1 TAS Homo sapiens 30616 R-HSA-5218826 https://reactome.org/PathwayBrowser/#/R-HSA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 TAS Homo sapiens 30616 R-HSA-5218828 https://reactome.org/PathwayBrowser/#/R-HSA-5218828 PTK2/SRC-1 phosphorylates BCAR1 IEA Homo sapiens 30616 R-HSA-5218830 https://reactome.org/PathwayBrowser/#/R-HSA-5218830 SRC-1 phosphorylates PTK2-beta TAS Homo sapiens 30616 R-HSA-5218845 https://reactome.org/PathwayBrowser/#/R-HSA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate TAS Homo sapiens 30616 R-HSA-5218851 https://reactome.org/PathwayBrowser/#/R-HSA-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 TAS Homo sapiens 30616 R-HSA-5218854 https://reactome.org/PathwayBrowser/#/R-HSA-5218854 p-Y420-FYN is phosphorylated on S21 TAS Homo sapiens 30616 R-HSA-5218906 https://reactome.org/PathwayBrowser/#/R-HSA-5218906 RIPK3 phosphorylates MLKL TAS Homo sapiens 30616 R-HSA-5218916 https://reactome.org/PathwayBrowser/#/R-HSA-5218916 p-MAPK2/3 phosphorylates HSP27 TAS Homo sapiens 30616 R-HSA-5223313 https://reactome.org/PathwayBrowser/#/R-HSA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) TAS Homo sapiens 30616 R-HSA-5223317 https://reactome.org/PathwayBrowser/#/R-HSA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen TAS Homo sapiens 30616 R-HSA-5228811 https://reactome.org/PathwayBrowser/#/R-HSA-5228811 NFKBIA variant is not phosphorylated within IkBA:NF-kappaB TAS Homo sapiens 30616 R-HSA-5229194 https://reactome.org/PathwayBrowser/#/R-HSA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation TAS Homo sapiens 30616 R-HSA-5229343 https://reactome.org/PathwayBrowser/#/R-HSA-5229343 AXIN is phosphorylated in the destruction complex TAS Homo sapiens 30616 R-HSA-5244669 https://reactome.org/PathwayBrowser/#/R-HSA-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments TAS Homo sapiens 30616 R-HSA-5251942 https://reactome.org/PathwayBrowser/#/R-HSA-5251942 Hikeshi binds HSP70s:ATP TAS Homo sapiens 30616 R-HSA-5251955 https://reactome.org/PathwayBrowser/#/R-HSA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm TAS Homo sapiens 30616 R-HSA-5251959 https://reactome.org/PathwayBrowser/#/R-HSA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol TAS Homo sapiens 30616 R-HSA-5251989 https://reactome.org/PathwayBrowser/#/R-HSA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol TAS Homo sapiens 30616 R-HSA-5252041 https://reactome.org/PathwayBrowser/#/R-HSA-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm TAS Homo sapiens 30616 R-HSA-5252079 https://reactome.org/PathwayBrowser/#/R-HSA-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP TAS Homo sapiens 30616 R-HSA-5260201 https://reactome.org/PathwayBrowser/#/R-HSA-5260201 p-AKT2 phosphorylates C2CD5 IEA Homo sapiens 30616 R-HSA-5339524 https://reactome.org/PathwayBrowser/#/R-HSA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol TAS Homo sapiens 30616 R-HSA-5357429 https://reactome.org/PathwayBrowser/#/R-HSA-5357429 AXL autophosphorylates on Y779 and Y821 TAS Homo sapiens 30616 R-HSA-5357472 https://reactome.org/PathwayBrowser/#/R-HSA-5357472 PAK1-3 autophosphorylates TAS Homo sapiens 30616 R-HSA-5357477 https://reactome.org/PathwayBrowser/#/R-HSA-5357477 PAK1-3 phosphorylates VE-cadherin TAS Homo sapiens 30616 R-HSA-5357831 https://reactome.org/PathwayBrowser/#/R-HSA-5357831 CHUK, IKBKB phosphorylate CYLD at S418 TAS Homo sapiens 30616 R-HSA-5357927 https://reactome.org/PathwayBrowser/#/R-HSA-5357927 MLKL oligomerizes TAS Homo sapiens 30616 R-HSA-5358475 https://reactome.org/PathwayBrowser/#/R-HSA-5358475 DPH6 ligates ammonium to diphthine-EEF2 TAS Homo sapiens 30616 R-HSA-5358510 https://reactome.org/PathwayBrowser/#/R-HSA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA TAS Homo sapiens 30616 R-HSA-5358512 https://reactome.org/PathwayBrowser/#/R-HSA-5358512 MLH1:PMS2 makes single strand incision near insertion/deletion loop of 2 bases or more IEA Homo sapiens 30616 R-HSA-5358518 https://reactome.org/PathwayBrowser/#/R-HSA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch TAS Homo sapiens 30616 R-HSA-5358519 https://reactome.org/PathwayBrowser/#/R-HSA-5358519 MSH2:MSH3 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Homo sapiens 30616 R-HSA-5358545 https://reactome.org/PathwayBrowser/#/R-HSA-5358545 EXO1 interacts with MSH2:MSH3 (MutSbeta) and MLH1:PMS2 (MutLalpha) IEA Homo sapiens 30616 R-HSA-5358592 https://reactome.org/PathwayBrowser/#/R-HSA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA TAS Homo sapiens 30616 R-HSA-5358597 https://reactome.org/PathwayBrowser/#/R-HSA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) TAS Homo sapiens 30616 R-HSA-5358599 https://reactome.org/PathwayBrowser/#/R-HSA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch TAS Homo sapiens 30616 R-HSA-5358619 https://reactome.org/PathwayBrowser/#/R-HSA-5358619 EXO1 interacting with MSH2:MSH3 excises DNA strand containing an insertion/deletion loop (IDL) IEA Homo sapiens 30616 R-HSA-5358912 https://reactome.org/PathwayBrowser/#/R-HSA-5358912 MSH2:MSH6 exchanges ADP for ATP TAS Homo sapiens 30616 R-HSA-5358919 https://reactome.org/PathwayBrowser/#/R-HSA-5358919 MSH2:MSH3 exchanges ADP for ATP IEA Homo sapiens 30616 R-HSA-5362459 https://reactome.org/PathwayBrowser/#/R-HSA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol TAS Homo sapiens 30616 R-HSA-5387389 https://reactome.org/PathwayBrowser/#/R-HSA-5387389 Hh processing variants are translocated to the cytosol in a VCP-dependent manner TAS Homo sapiens 30616 R-HSA-548843 https://reactome.org/PathwayBrowser/#/R-HSA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA TAS Homo sapiens 30616 R-HSA-5578777 https://reactome.org/PathwayBrowser/#/R-HSA-5578777 DMPK phosphorylates PLN TAS Homo sapiens 30616 R-HSA-5602892 https://reactome.org/PathwayBrowser/#/R-HSA-5602892 Defective GCLC does not ligate L-Glu to L-Cys TAS Homo sapiens 30616 R-HSA-5602901 https://reactome.org/PathwayBrowser/#/R-HSA-5602901 Defective GSS does not synthesize GSH TAS Homo sapiens 30616 R-HSA-5603087 https://reactome.org/PathwayBrowser/#/R-HSA-5603087 Defective MAT1A does not transfer Ado from ATP to L-Met TAS Homo sapiens 30616 R-HSA-5603114 https://reactome.org/PathwayBrowser/#/R-HSA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met TAS Homo sapiens 30616 R-HSA-5603208 https://reactome.org/PathwayBrowser/#/R-HSA-5603208 Defective OPLAH does not hydrolyse OPRO TAS Homo sapiens 30616 R-HSA-5607722 https://reactome.org/PathwayBrowser/#/R-HSA-5607722 Active NIK phosphorylates IKKA dimer TAS Homo sapiens 30616 R-HSA-5607726 https://reactome.org/PathwayBrowser/#/R-HSA-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB TAS Homo sapiens 30616 R-HSA-5607732 https://reactome.org/PathwayBrowser/#/R-HSA-5607732 K63polyUb-TAK1 autophosphorylates TAS Homo sapiens 30616 R-HSA-5607740 https://reactome.org/PathwayBrowser/#/R-HSA-5607740 PKC-delta phosphorylates CARD9 TAS Homo sapiens 30616 R-HSA-5607742 https://reactome.org/PathwayBrowser/#/R-HSA-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta TAS Homo sapiens 30616 R-HSA-5607745 https://reactome.org/PathwayBrowser/#/R-HSA-5607745 1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG IEA Homo sapiens 30616 R-HSA-5607750 https://reactome.org/PathwayBrowser/#/R-HSA-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan TAS Homo sapiens 30616 R-HSA-5607756 https://reactome.org/PathwayBrowser/#/R-HSA-5607756 TRAF6 oligomer autoubiquitinates TAS Homo sapiens 30616 R-HSA-5607757 https://reactome.org/PathwayBrowser/#/R-HSA-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 TAS Homo sapiens 30616 R-HSA-5610026 https://reactome.org/PathwayBrowser/#/R-HSA-5610026 Defective GALK1 does not phosphorylate Gal TAS Homo sapiens 30616 R-HSA-5610717 https://reactome.org/PathwayBrowser/#/R-HSA-5610717 PKA phosphorylates GLI2 IEA Homo sapiens 30616 R-HSA-5610718 https://reactome.org/PathwayBrowser/#/R-HSA-5610718 CK1 phosphorylates p-GLI2 IEA Homo sapiens 30616 R-HSA-5610720 https://reactome.org/PathwayBrowser/#/R-HSA-5610720 PKA phosphorylates GLI3 TAS Homo sapiens 30616 R-HSA-5610722 https://reactome.org/PathwayBrowser/#/R-HSA-5610722 CK1 phosphorylates p-GLI3 TAS Homo sapiens 30616 R-HSA-5610727 https://reactome.org/PathwayBrowser/#/R-HSA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner TAS Homo sapiens 30616 R-HSA-5610730 https://reactome.org/PathwayBrowser/#/R-HSA-5610730 GSK3 phosphorylates p-GLI2 IEA Homo sapiens 30616 R-HSA-5610732 https://reactome.org/PathwayBrowser/#/R-HSA-5610732 GSK3 phosphorylates p-GLI3 TAS Homo sapiens 30616 R-HSA-5610741 https://reactome.org/PathwayBrowser/#/R-HSA-5610741 PKA phosphorylates GLI1 IEA Homo sapiens 30616 R-HSA-5617179 https://reactome.org/PathwayBrowser/#/R-HSA-5617179 PRKACA phosphorylates TNNI3 TAS Homo sapiens 30616 R-HSA-5617182 https://reactome.org/PathwayBrowser/#/R-HSA-5617182 PRKACA phosphorylates PLN TAS Homo sapiens 30616 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 30616 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 30616 R-HSA-5618085 https://reactome.org/PathwayBrowser/#/R-HSA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein TAS Homo sapiens 30616 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 30616 R-HSA-5618098 https://reactome.org/PathwayBrowser/#/R-HSA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein TAS Homo sapiens 30616 R-HSA-5618099 https://reactome.org/PathwayBrowser/#/R-HSA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) TAS Homo sapiens 30616 R-HSA-5618105 https://reactome.org/PathwayBrowser/#/R-HSA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein TAS Homo sapiens 30616 R-HSA-5618107 https://reactome.org/PathwayBrowser/#/R-HSA-5618107 ATP binding to HSP90 triggers conformation change TAS Homo sapiens 30616 R-HSA-5618110 https://reactome.org/PathwayBrowser/#/R-HSA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein TAS Homo sapiens 30616 R-HSA-5621355 https://reactome.org/PathwayBrowser/#/R-HSA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG TAS Homo sapiens 30616 R-HSA-5621363 https://reactome.org/PathwayBrowser/#/R-HSA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 TAS Homo sapiens 30616 R-HSA-5621370 https://reactome.org/PathwayBrowser/#/R-HSA-5621370 SYK autophosphorylates TAS Homo sapiens 30616 R-HSA-5621888 https://reactome.org/PathwayBrowser/#/R-HSA-5621888 Defective HK1 does not phosphorylate Glc to form G6P TAS Homo sapiens 30616 R-HSA-5621918 https://reactome.org/PathwayBrowser/#/R-HSA-5621918 Defective GCK does not phosphorylate Glc to form G6P TAS Homo sapiens 30616 R-HSA-5623667 https://reactome.org/PathwayBrowser/#/R-HSA-5623667 PDPK1 phosphorylates PKN1,2,3 TAS Homo sapiens 30616 R-HSA-5624473 https://reactome.org/PathwayBrowser/#/R-HSA-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit TAS Homo sapiens 30616 R-HSA-5624486 https://reactome.org/PathwayBrowser/#/R-HSA-5624486 SFKs phosphorylates RAF1 on Y340,Y341 TAS Homo sapiens 30616 R-HSA-5624492 https://reactome.org/PathwayBrowser/#/R-HSA-5624492 PAK phosphorylates p21 RAF1 on S338 TAS Homo sapiens 30616 R-HSA-5625784 https://reactome.org/PathwayBrowser/#/R-HSA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters TAS Homo sapiens 30616 R-HSA-5626507 https://reactome.org/PathwayBrowser/#/R-HSA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin TAS Homo sapiens 30616 R-HSA-5627775 https://reactome.org/PathwayBrowser/#/R-HSA-5627775 Autophosphorylation of PAK1,2,3 TAS Homo sapiens 30616 R-HSA-5632670 https://reactome.org/PathwayBrowser/#/R-HSA-5632670 CSNK1A1 phosphorylates SMO dimer IEA Homo sapiens 30616 R-HSA-5632672 https://reactome.org/PathwayBrowser/#/R-HSA-5632672 ADRBK1 phosphorylates SMO dimer IEA Homo sapiens 30616 R-HSA-5635841 https://reactome.org/PathwayBrowser/#/R-HSA-5635841 GLI proteins are phosphorylated TAS Homo sapiens 30616 R-HSA-5635842 https://reactome.org/PathwayBrowser/#/R-HSA-5635842 ULK3 phosphorylates GLI TAS Homo sapiens 30616 R-HSA-5637795 https://reactome.org/PathwayBrowser/#/R-HSA-5637795 Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant TAS Homo sapiens 30616 R-HSA-5637796 https://reactome.org/PathwayBrowser/#/R-HSA-5637796 Phosphorylation of SHC1 by p-5Y-EGFRvIII TAS Homo sapiens 30616 R-HSA-5637801 https://reactome.org/PathwayBrowser/#/R-HSA-5637801 Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII TAS Homo sapiens 30616 R-HSA-5654147 https://reactome.org/PathwayBrowser/#/R-HSA-5654147 Activated FGFR2 phosphorylates PLCG1 TAS Homo sapiens 30616 R-HSA-5654149 https://reactome.org/PathwayBrowser/#/R-HSA-5654149 Activated FGFR1 phosphorylates PLCG1 TAS Homo sapiens 30616 R-HSA-5654151 https://reactome.org/PathwayBrowser/#/R-HSA-5654151 Activated FGFR4 phosphorylates PLCG1 TAS Homo sapiens 30616 R-HSA-5654222 https://reactome.org/PathwayBrowser/#/R-HSA-5654222 Activated FGFR3 phosphorylates PLCG1 TAS Homo sapiens 30616 R-HSA-5654397 https://reactome.org/PathwayBrowser/#/R-HSA-5654397 Activated FGFR2 phosphorylates FRS2 TAS Homo sapiens 30616 R-HSA-5654407 https://reactome.org/PathwayBrowser/#/R-HSA-5654407 Activated FGFR2 phosphorylates SHC1 TAS Homo sapiens 30616 R-HSA-5654408 https://reactome.org/PathwayBrowser/#/R-HSA-5654408 Activated FGFR3 phosphorylates FRS2 TAS Homo sapiens 30616 R-HSA-5654418 https://reactome.org/PathwayBrowser/#/R-HSA-5654418 Activated FGFR4 phosphorylates FRS2 TAS Homo sapiens 30616 R-HSA-5654428 https://reactome.org/PathwayBrowser/#/R-HSA-5654428 Activated FGFR4 phosphorylates SHC1 TAS Homo sapiens 30616 R-HSA-5654545 https://reactome.org/PathwayBrowser/#/R-HSA-5654545 Ligand-independent phosphorylation of overexpressed FGFR1c TAS Homo sapiens 30616 R-HSA-5654560 https://reactome.org/PathwayBrowser/#/R-HSA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. TAS Homo sapiens 30616 R-HSA-5654562 https://reactome.org/PathwayBrowser/#/R-HSA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 TAS Homo sapiens 30616 R-HSA-5654565 https://reactome.org/PathwayBrowser/#/R-HSA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. TAS Homo sapiens 30616 R-HSA-5654566 https://reactome.org/PathwayBrowser/#/R-HSA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. TAS Homo sapiens 30616 R-HSA-5654575 https://reactome.org/PathwayBrowser/#/R-HSA-5654575 Activated FGFR1 phosphorylates FRS2 TAS Homo sapiens 30616 R-HSA-5654578 https://reactome.org/PathwayBrowser/#/R-HSA-5654578 Activated FGFR1 phosphorylates FRS3 TAS Homo sapiens 30616 R-HSA-5654582 https://reactome.org/PathwayBrowser/#/R-HSA-5654582 Activated FGFR1 phosphorylates SHC1 TAS Homo sapiens 30616 R-HSA-5654587 https://reactome.org/PathwayBrowser/#/R-HSA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 TAS Homo sapiens 30616 R-HSA-5654605 https://reactome.org/PathwayBrowser/#/R-HSA-5654605 Activated FGFR2 phosphorylates FRS3 TAS Homo sapiens 30616 R-HSA-5654607 https://reactome.org/PathwayBrowser/#/R-HSA-5654607 Activated FGFR2 phosphorylates PPTN11 TAS Homo sapiens 30616 R-HSA-5654628 https://reactome.org/PathwayBrowser/#/R-HSA-5654628 Activated FGFR3 phosphorylates FRS3 TAS Homo sapiens 30616 R-HSA-5654631 https://reactome.org/PathwayBrowser/#/R-HSA-5654631 Activated FGFR3 phosphorylates PPTN11 TAS Homo sapiens 30616 R-HSA-5654634 https://reactome.org/PathwayBrowser/#/R-HSA-5654634 Activated FGFR3 phosphorylates SHC1 TAS Homo sapiens 30616 R-HSA-5654653 https://reactome.org/PathwayBrowser/#/R-HSA-5654653 Activated FGFR4 phosphorylates FRS3 TAS Homo sapiens 30616 R-HSA-5654655 https://reactome.org/PathwayBrowser/#/R-HSA-5654655 Activated FGFR4 phosphorylates PPTN11 TAS Homo sapiens 30616 R-HSA-5654690 https://reactome.org/PathwayBrowser/#/R-HSA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5654692 https://reactome.org/PathwayBrowser/#/R-HSA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5654697 https://reactome.org/PathwayBrowser/#/R-HSA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5654701 https://reactome.org/PathwayBrowser/#/R-HSA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5654705 https://reactome.org/PathwayBrowser/#/R-HSA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5654709 https://reactome.org/PathwayBrowser/#/R-HSA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5654714 https://reactome.org/PathwayBrowser/#/R-HSA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5654717 https://reactome.org/PathwayBrowser/#/R-HSA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5654989 https://reactome.org/PathwayBrowser/#/R-HSA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA TAS Homo sapiens 30616 R-HSA-5655235 https://reactome.org/PathwayBrowser/#/R-HSA-5655235 Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5655243 https://reactome.org/PathwayBrowser/#/R-HSA-5655243 Activated FGFR3 point and translocation mutants phosphorylate PLCG1 TAS Homo sapiens 30616 R-HSA-5655268 https://reactome.org/PathwayBrowser/#/R-HSA-5655268 Activated FGFR2 mutants phosphorylate FRS2 TAS Homo sapiens 30616 R-HSA-5655270 https://reactome.org/PathwayBrowser/#/R-HSA-5655270 Activated FGFR3 point, translocation and fusion mutants phosphorylate FRS2 TAS Homo sapiens 30616 R-HSA-5655278 https://reactome.org/PathwayBrowser/#/R-HSA-5655278 Activated FGFR1 mutants phosphorylate FRS2 TAS Homo sapiens 30616 R-HSA-5655284 https://reactome.org/PathwayBrowser/#/R-HSA-5655284 Activated FGFR4 mutants phosphorylate FRS2 TAS Homo sapiens 30616 R-HSA-5655289 https://reactome.org/PathwayBrowser/#/R-HSA-5655289 Activated FGFR3 point, translocation and fusion mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5655290 https://reactome.org/PathwayBrowser/#/R-HSA-5655290 Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5655301 https://reactome.org/PathwayBrowser/#/R-HSA-5655301 Activated FGFR2 mutants phosphorylate PLCG1 TAS Homo sapiens 30616 R-HSA-5655323 https://reactome.org/PathwayBrowser/#/R-HSA-5655323 Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-5655341 https://reactome.org/PathwayBrowser/#/R-HSA-5655341 Activated FGFR4 mutants phosphorylate PLCG1 TAS Homo sapiens 30616 R-HSA-5656459 https://reactome.org/PathwayBrowser/#/R-HSA-5656459 Defective KHK does not phosphorylate beta-D-fructose TAS Homo sapiens 30616 R-HSA-5662466 https://reactome.org/PathwayBrowser/#/R-HSA-5662466 XYLB phosphorylates D-xylulose TAS Homo sapiens 30616 R-HSA-5665659 https://reactome.org/PathwayBrowser/#/R-HSA-5665659 RAC1:GTP:FMNL1 binds profilin:G-actin IEA Homo sapiens 30616 R-HSA-5665751 https://reactome.org/PathwayBrowser/#/R-HSA-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin TAS Homo sapiens 30616 R-HSA-5665767 https://reactome.org/PathwayBrowser/#/R-HSA-5665767 Activated FMNL3 binds G-actin TAS Homo sapiens 30616 R-HSA-5665802 https://reactome.org/PathwayBrowser/#/R-HSA-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin TAS Homo sapiens 30616 R-HSA-5665809 https://reactome.org/PathwayBrowser/#/R-HSA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments TAS Homo sapiens 30616 R-HSA-5665868 https://reactome.org/PathwayBrowser/#/R-HSA-5665868 AMPK (complex) phosphorylates ULK1 (complex) TAS Homo sapiens 30616 R-HSA-5665982 https://reactome.org/PathwayBrowser/#/R-HSA-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 TAS Homo sapiens 30616 R-HSA-5666001 https://reactome.org/PathwayBrowser/#/R-HSA-5666001 Profilin:G-actin binds MKL1 TAS Homo sapiens 30616 R-HSA-5666160 https://reactome.org/PathwayBrowser/#/R-HSA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores TAS Homo sapiens 30616 R-HSA-5668545 https://reactome.org/PathwayBrowser/#/R-HSA-5668545 NIK autophosphorylates on T559 TAS Homo sapiens 30616 R-HSA-5668932 https://reactome.org/PathwayBrowser/#/R-HSA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) TAS Homo sapiens 30616 R-HSA-5668947 https://reactome.org/PathwayBrowser/#/R-HSA-5668947 PAK1 phosphorylates myosin phosphatase TAS Homo sapiens 30616 R-HSA-5668978 https://reactome.org/PathwayBrowser/#/R-HSA-5668978 MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex IEA Homo sapiens 30616 R-HSA-5668984 https://reactome.org/PathwayBrowser/#/R-HSA-5668984 PAK1 or PAK2 phosphorylates MYLK TAS Homo sapiens 30616 R-HSA-5669250 https://reactome.org/PathwayBrowser/#/R-HSA-5669250 PAK1 phosphorylates FLNA TAS Homo sapiens 30616 R-HSA-5671749 https://reactome.org/PathwayBrowser/#/R-HSA-5671749 p-T774-PKN1 phosphorylates CDC25C TAS Homo sapiens 30616 R-HSA-5671763 https://reactome.org/PathwayBrowser/#/R-HSA-5671763 p-T774-PKN1 phosphorylates PPP1R14A TAS Homo sapiens 30616 R-HSA-5671919 https://reactome.org/PathwayBrowser/#/R-HSA-5671919 Activated CIT phosphorylates MRLCs IEA Homo sapiens 30616 R-HSA-5672008 https://reactome.org/PathwayBrowser/#/R-HSA-5672008 Thr-180 of ULK1 is phosphorylated TAS Homo sapiens 30616 R-HSA-5672010 https://reactome.org/PathwayBrowser/#/R-HSA-5672010 Active MTORC1 phosphorylates ULK1 TAS Homo sapiens 30616 R-HSA-5672012 https://reactome.org/PathwayBrowser/#/R-HSA-5672012 Beclin-1 complex phosphorylates PtdIns TAS Homo sapiens 30616 R-HSA-5672027 https://reactome.org/PathwayBrowser/#/R-HSA-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane TAS Homo sapiens 30616 R-HSA-5672828 https://reactome.org/PathwayBrowser/#/R-HSA-5672828 mTORC1 phosphorylates AKT1S1 TAS Homo sapiens 30616 R-HSA-5672948 https://reactome.org/PathwayBrowser/#/R-HSA-5672948 MARK3 phosphorylates KSR1 TAS Homo sapiens 30616 R-HSA-5672969 https://reactome.org/PathwayBrowser/#/R-HSA-5672969 Phosphorylation of RAF TAS Homo sapiens 30616 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 30616 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 30616 R-HSA-5673768 https://reactome.org/PathwayBrowser/#/R-HSA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex TAS Homo sapiens 30616 R-HSA-5674130 https://reactome.org/PathwayBrowser/#/R-HSA-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane TAS Homo sapiens 30616 R-HSA-5674373 https://reactome.org/PathwayBrowser/#/R-HSA-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane TAS Homo sapiens 30616 R-HSA-5674496 https://reactome.org/PathwayBrowser/#/R-HSA-5674496 Activated MAPKs phosphorylate MAP2K1 TAS Homo sapiens 30616 R-HSA-5675194 https://reactome.org/PathwayBrowser/#/R-HSA-5675194 Activated MAPK phosphorylates RAF1 TAS Homo sapiens 30616 R-HSA-5675198 https://reactome.org/PathwayBrowser/#/R-HSA-5675198 Activated MAPKs phosphorylate BRAF TAS Homo sapiens 30616 R-HSA-5675868 https://reactome.org/PathwayBrowser/#/R-HSA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 TAS Homo sapiens 30616 R-HSA-5678517 https://reactome.org/PathwayBrowser/#/R-HSA-5678517 Defective ABCB11 does not transport bile salts from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-5678706 https://reactome.org/PathwayBrowser/#/R-HSA-5678706 ABCB4 transports PC from plasma membrane to extracellular region TAS Homo sapiens 30616 R-HSA-5678749 https://reactome.org/PathwayBrowser/#/R-HSA-5678749 Defective ABCB4 does not transport PC from plasma membrane to extracellular region TAS Homo sapiens 30616 R-HSA-5678822 https://reactome.org/PathwayBrowser/#/R-HSA-5678822 Defective CFTR does not transport Cl- from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-5678863 https://reactome.org/PathwayBrowser/#/R-HSA-5678863 CFTR transports Cl- from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-5678992 https://reactome.org/PathwayBrowser/#/R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-5679031 https://reactome.org/PathwayBrowser/#/R-HSA-5679031 Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-5679041 https://reactome.org/PathwayBrowser/#/R-HSA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-5679101 https://reactome.org/PathwayBrowser/#/R-HSA-5679101 Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-5679145 https://reactome.org/PathwayBrowser/#/R-HSA-5679145 Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-5679205 https://reactome.org/PathwayBrowser/#/R-HSA-5679205 ULK1 phosphorylates Beclin-1 TAS Homo sapiens 30616 R-HSA-5682026 https://reactome.org/PathwayBrowser/#/R-HSA-5682026 MRN bound to shortened telomeres activates ATM TAS Homo sapiens 30616 R-HSA-5682101 https://reactome.org/PathwayBrowser/#/R-HSA-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer TAS Homo sapiens 30616 R-HSA-5682111 https://reactome.org/PathwayBrowser/#/R-HSA-5682111 Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 30616 R-HSA-5682285 https://reactome.org/PathwayBrowser/#/R-HSA-5682285 ABCA12 transports lipids from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-5682311 https://reactome.org/PathwayBrowser/#/R-HSA-5682311 Defective ABCA12 does not transport lipids from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-5682598 https://reactome.org/PathwayBrowser/#/R-HSA-5682598 ATM phosphorylates HERC2 TAS Homo sapiens 30616 R-HSA-5682983 https://reactome.org/PathwayBrowser/#/R-HSA-5682983 ATM phosphorylates WHSC1 TAS Homo sapiens 30616 R-HSA-5683113 https://reactome.org/PathwayBrowser/#/R-HSA-5683113 Defective ABCC8 does not form functional KATP channels, causing hyperinsulinemic hypoglycemia TAS Homo sapiens 30616 R-HSA-5683325 https://reactome.org/PathwayBrowser/#/R-HSA-5683325 Defective ABCD4:LMBRD1 does not transport Cbl from lysosomal lumen to cytosol TAS Homo sapiens 30616 R-HSA-5683355 https://reactome.org/PathwayBrowser/#/R-HSA-5683355 Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix TAS Homo sapiens 30616 R-HSA-5683425 https://reactome.org/PathwayBrowser/#/R-HSA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs TAS Homo sapiens 30616 R-HSA-5683672 https://reactome.org/PathwayBrowser/#/R-HSA-5683672 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body TAS Homo sapiens 30616 R-HSA-5683714 https://reactome.org/PathwayBrowser/#/R-HSA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body TAS Homo sapiens 30616 R-HSA-5683792 https://reactome.org/PathwayBrowser/#/R-HSA-5683792 p-T68-CHEK2 autophosphorylates TAS Homo sapiens 30616 R-HSA-5683801 https://reactome.org/PathwayBrowser/#/R-HSA-5683801 CHEK2 phosphorylates BRCA1 TAS Homo sapiens 30616 R-HSA-5683930 https://reactome.org/PathwayBrowser/#/R-HSA-5683930 WICH phosphorylates H2AFX on Y142 TAS Homo sapiens 30616 R-HSA-5683964 https://reactome.org/PathwayBrowser/#/R-HSA-5683964 ATM phosphorylates EYA1-4 TAS Homo sapiens 30616 R-HSA-5684043 https://reactome.org/PathwayBrowser/#/R-HSA-5684043 Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix TAS Homo sapiens 30616 R-HSA-5684096 https://reactome.org/PathwayBrowser/#/R-HSA-5684096 CDK2 phosphorylates RBBP8 TAS Homo sapiens 30616 R-HSA-5684140 https://reactome.org/PathwayBrowser/#/R-HSA-5684140 ATM phosphorylates RBBP8 TAS Homo sapiens 30616 R-HSA-5684261 https://reactome.org/PathwayBrowser/#/R-HSA-5684261 MAP3K8 is phosphorylated TAS Homo sapiens 30616 R-HSA-5684267 https://reactome.org/PathwayBrowser/#/R-HSA-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex TAS Homo sapiens 30616 R-HSA-5684275 https://reactome.org/PathwayBrowser/#/R-HSA-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 TAS Homo sapiens 30616 R-HSA-5684806 https://reactome.org/PathwayBrowser/#/R-HSA-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN TAS Homo sapiens 30616 R-HSA-5684862 https://reactome.org/PathwayBrowser/#/R-HSA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. TAS Homo sapiens 30616 R-HSA-5684887 https://reactome.org/PathwayBrowser/#/R-HSA-5684887 Activation of CHEK1 at resected DNA DSBs TAS Homo sapiens 30616 R-HSA-5685156 https://reactome.org/PathwayBrowser/#/R-HSA-5685156 ATR phosphorylates RPA2 TAS Homo sapiens 30616 R-HSA-5685230 https://reactome.org/PathwayBrowser/#/R-HSA-5685230 CHEK1 phosphorylates RAD51 TAS Homo sapiens 30616 R-HSA-5685242 https://reactome.org/PathwayBrowser/#/R-HSA-5685242 CHEK1 phosphorylates BRCA2 TAS Homo sapiens 30616 R-HSA-5686410 https://reactome.org/PathwayBrowser/#/R-HSA-5686410 BLM mediates dissolution of double Holliday junction TAS Homo sapiens 30616 R-HSA-5686578 https://reactome.org/PathwayBrowser/#/R-HSA-5686578 Activated ATM phosphorylates ABL1 TAS Homo sapiens 30616 R-HSA-5686587 https://reactome.org/PathwayBrowser/#/R-HSA-5686587 ABL1 phosphorylates RAD52 TAS Homo sapiens 30616 R-HSA-5686704 https://reactome.org/PathwayBrowser/#/R-HSA-5686704 Activated ATM phosphorylates DCLRE1C TAS Homo sapiens 30616 R-HSA-5687086 https://reactome.org/PathwayBrowser/#/R-HSA-5687086 PAK1,2,3 phosphorylates MAPK6,4 TAS Homo sapiens 30616 R-HSA-5687088 https://reactome.org/PathwayBrowser/#/R-HSA-5687088 PKA phosphorylates MAPKAPK5 TAS Homo sapiens 30616 R-HSA-5687090 https://reactome.org/PathwayBrowser/#/R-HSA-5687090 p-S MAPK6 phosphorylates NCOA3 TAS Homo sapiens 30616 R-HSA-5687094 https://reactome.org/PathwayBrowser/#/R-HSA-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 TAS Homo sapiens 30616 R-HSA-5687101 https://reactome.org/PathwayBrowser/#/R-HSA-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 TAS Homo sapiens 30616 R-HSA-5687121 https://reactome.org/PathwayBrowser/#/R-HSA-5687121 p-S MAPKAPK5 phosphorylates HSPB1 TAS Homo sapiens 30616 R-HSA-5687183 https://reactome.org/PathwayBrowser/#/R-HSA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs TAS Homo sapiens 30616 R-HSA-5688397 https://reactome.org/PathwayBrowser/#/R-HSA-5688397 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body TAS Homo sapiens 30616 R-HSA-5690250 https://reactome.org/PathwayBrowser/#/R-HSA-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 TAS Homo sapiens 30616 R-HSA-5690340 https://reactome.org/PathwayBrowser/#/R-HSA-5690340 Defective ABCC6 does not transport organic anion from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-5690702 https://reactome.org/PathwayBrowser/#/R-HSA-5690702 LYN phosphorylates CD22 TAS Homo sapiens 30616 R-HSA-5690996 https://reactome.org/PathwayBrowser/#/R-HSA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA TAS Homo sapiens 30616 R-HSA-5692462 https://reactome.org/PathwayBrowser/#/R-HSA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen TAS Homo sapiens 30616 R-HSA-5692480 https://reactome.org/PathwayBrowser/#/R-HSA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen TAS Homo sapiens 30616 R-HSA-5692755 https://reactome.org/PathwayBrowser/#/R-HSA-5692755 CDK1 phosphorylates MAPK6 TAS Homo sapiens 30616 R-HSA-5692768 https://reactome.org/PathwayBrowser/#/R-HSA-5692768 MAPKAPK5 phosphorylates KALRN TAS Homo sapiens 30616 R-HSA-5692775 https://reactome.org/PathwayBrowser/#/R-HSA-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs TAS Homo sapiens 30616 R-HSA-5692779 https://reactome.org/PathwayBrowser/#/R-HSA-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 TAS Homo sapiens 30616 R-HSA-5693148 https://reactome.org/PathwayBrowser/#/R-HSA-5693148 BCKDK phosphorylates BCKDH TAS Homo sapiens 30616 R-HSA-5693536 https://reactome.org/PathwayBrowser/#/R-HSA-5693536 ATM phosphorylates MDC1 TAS Homo sapiens 30616 R-HSA-5693540 https://reactome.org/PathwayBrowser/#/R-HSA-5693540 MRN activates ATM TAS Homo sapiens 30616 R-HSA-5693549 https://reactome.org/PathwayBrowser/#/R-HSA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs TAS Homo sapiens 30616 R-HSA-5693551 https://reactome.org/PathwayBrowser/#/R-HSA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM TAS Homo sapiens 30616 R-HSA-5693575 https://reactome.org/PathwayBrowser/#/R-HSA-5693575 DNA-PKcs autophosphorylates TAS Homo sapiens 30616 R-HSA-5693589 https://reactome.org/PathwayBrowser/#/R-HSA-5693589 D-loop dissociation and strand annealing TAS Homo sapiens 30616 R-HSA-5693598 https://reactome.org/PathwayBrowser/#/R-HSA-5693598 ATM phosphorylates NBN TAS Homo sapiens 30616 R-HSA-5693609 https://reactome.org/PathwayBrowser/#/R-HSA-5693609 ATM phosphorylates TP53 at S15 TAS Homo sapiens 30616 R-HSA-5694425 https://reactome.org/PathwayBrowser/#/R-HSA-5694425 NSF ATPase activity dissociates cis-SNARE TAS Homo sapiens 30616 R-HSA-5694441 https://reactome.org/PathwayBrowser/#/R-HSA-5694441 CSNK1D phosphorylates SEC23 TAS Homo sapiens 30616 R-HSA-5694494 https://reactome.org/PathwayBrowser/#/R-HSA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA TAS Homo sapiens 30616 R-HSA-5695957 https://reactome.org/PathwayBrowser/#/R-HSA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA TAS Homo sapiens 30616 R-HSA-5696004 https://reactome.org/PathwayBrowser/#/R-HSA-5696004 ACSF2 ligates CoA-SH to MCFA TAS Homo sapiens 30616 R-HSA-5696007 https://reactome.org/PathwayBrowser/#/R-HSA-5696007 ACSF3 ligates CoA-SH to VLCFA TAS Homo sapiens 30616 R-HSA-5696074 https://reactome.org/PathwayBrowser/#/R-HSA-5696074 AGK:Mg2+ phosphorylates MAG, DAG TAS Homo sapiens 30616 R-HSA-5696807 https://reactome.org/PathwayBrowser/#/R-HSA-5696807 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 30616 R-HSA-5696816 https://reactome.org/PathwayBrowser/#/R-HSA-5696816 tRNA ligase complex ligates tRNA exons TAS Homo sapiens 30616 R-HSA-5696839 https://reactome.org/PathwayBrowser/#/R-HSA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF TAS Homo sapiens 30616 R-HSA-593690 https://reactome.org/PathwayBrowser/#/R-HSA-593690 Phosphorylation of PLCgamma by Netrin-1 IEA Homo sapiens 30616 R-HSA-6782131 https://reactome.org/PathwayBrowser/#/R-HSA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER TAS Homo sapiens 30616 R-HSA-6782434 https://reactome.org/PathwayBrowser/#/R-HSA-6782434 THG1L transfers GMP to 5' end of tRNA(His) TAS Homo sapiens 30616 R-HSA-6784006 https://reactome.org/PathwayBrowser/#/R-HSA-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 TAS Homo sapiens 30616 R-HSA-6784319 https://reactome.org/PathwayBrowser/#/R-HSA-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 TAS Homo sapiens 30616 R-HSA-6784324 https://reactome.org/PathwayBrowser/#/R-HSA-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA TAS Homo sapiens 30616 R-HSA-6786050 https://reactome.org/PathwayBrowser/#/R-HSA-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated TAS Homo sapiens 30616 R-HSA-6786095 https://reactome.org/PathwayBrowser/#/R-HSA-6786095 JAK1 phosphorylates STAT3,STAT6 TAS Homo sapiens 30616 R-HSA-6786096 https://reactome.org/PathwayBrowser/#/R-HSA-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated TAS Homo sapiens 30616 R-HSA-6786245 https://reactome.org/PathwayBrowser/#/R-HSA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN TAS Homo sapiens 30616 R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 30616 R-HSA-6787540 https://reactome.org/PathwayBrowser/#/R-HSA-6787540 FUK phosphorylates beta-Fuc to Fuc1P TAS Homo sapiens 30616 R-HSA-6788392 https://reactome.org/PathwayBrowser/#/R-HSA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA TAS Homo sapiens 30616 R-HSA-6788582 https://reactome.org/PathwayBrowser/#/R-HSA-6788582 STAT1,STAT3,STAT6 phosphorylation TAS Homo sapiens 30616 R-HSA-6788798 https://reactome.org/PathwayBrowser/#/R-HSA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 30616 R-HSA-6788810 https://reactome.org/PathwayBrowser/#/R-HSA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 30616 R-HSA-6788855 https://reactome.org/PathwayBrowser/#/R-HSA-6788855 FN3KRP phosphorylates PsiAm, RibAm TAS Homo sapiens 30616 R-HSA-6788867 https://reactome.org/PathwayBrowser/#/R-HSA-6788867 FN3K phosphorylates ketosamines TAS Homo sapiens 30616 R-HSA-6790087 https://reactome.org/PathwayBrowser/#/R-HSA-6790087 HVEM induses BTLA phosphorylation IEA Homo sapiens 30616 R-HSA-6790987 https://reactome.org/PathwayBrowser/#/R-HSA-6790987 NAT10 acetylates cytidine-1337 and cytidine-1842 of 18S rRNA yielding 4-acetylcytidine-1377 and 4-acetylcytidine-1842 TAS Homo sapiens 30616 R-HSA-6793661 https://reactome.org/PathwayBrowser/#/R-HSA-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 TAS Homo sapiens 30616 R-HSA-6795290 https://reactome.org/PathwayBrowser/#/R-HSA-6795290 TORC2 complex phosphorylates SGK1 TAS Homo sapiens 30616 R-HSA-6795460 https://reactome.org/PathwayBrowser/#/R-HSA-6795460 SGK1 phosphorylates MDM2 TAS Homo sapiens 30616 R-HSA-6795473 https://reactome.org/PathwayBrowser/#/R-HSA-6795473 PDPK1 phosphorylates SGK1 TAS Homo sapiens 30616 R-HSA-6797606 https://reactome.org/PathwayBrowser/#/R-HSA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes TAS Homo sapiens 30616 R-HSA-6798174 https://reactome.org/PathwayBrowser/#/R-HSA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P TAS Homo sapiens 30616 R-HSA-6798345 https://reactome.org/PathwayBrowser/#/R-HSA-6798345 PXLP-GCAT dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA TAS Homo sapiens 30616 R-HSA-6798372 https://reactome.org/PathwayBrowser/#/R-HSA-6798372 ATM phosphorylates DYRK2 TAS Homo sapiens 30616 R-HSA-6798374 https://reactome.org/PathwayBrowser/#/R-HSA-6798374 DYRK2 phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6799097 https://reactome.org/PathwayBrowser/#/R-HSA-6799097 ATM phosphorylates ZNF420 TAS Homo sapiens 30616 R-HSA-6799246 https://reactome.org/PathwayBrowser/#/R-HSA-6799246 CHEK1 phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6799332 https://reactome.org/PathwayBrowser/#/R-HSA-6799332 ATR phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6799409 https://reactome.org/PathwayBrowser/#/R-HSA-6799409 HIPK2 phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6799495 https://reactome.org/PathwayBrowser/#/R-HSA-6799495 GLYCTK phosphorylates DGA to 3PDGA TAS Homo sapiens 30616 R-HSA-6800490 https://reactome.org/PathwayBrowser/#/R-HSA-6800490 ATM phosphorylates PIDD1 TAS Homo sapiens 30616 R-HSA-6801342 https://reactome.org/PathwayBrowser/#/R-HSA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG TAS Homo sapiens 30616 R-HSA-6801456 https://reactome.org/PathwayBrowser/#/R-HSA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF TAS Homo sapiens 30616 R-HSA-6801666 https://reactome.org/PathwayBrowser/#/R-HSA-6801666 PLK2 phosphorylates CENPJ TAS Homo sapiens 30616 R-HSA-6801675 https://reactome.org/PathwayBrowser/#/R-HSA-6801675 PLK2 phosphorylates NPM1 TAS Homo sapiens 30616 R-HSA-6802910 https://reactome.org/PathwayBrowser/#/R-HSA-6802910 Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants TAS Homo sapiens 30616 R-HSA-6802911 https://reactome.org/PathwayBrowser/#/R-HSA-6802911 High kinase activity BRAF complexes phosphorylate MAP2Ks TAS Homo sapiens 30616 R-HSA-6802916 https://reactome.org/PathwayBrowser/#/R-HSA-6802916 RAF is phosphorylated downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 30616 R-HSA-6802918 https://reactome.org/PathwayBrowser/#/R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants TAS Homo sapiens 30616 R-HSA-6802919 https://reactome.org/PathwayBrowser/#/R-HSA-6802919 RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 30616 R-HSA-6802921 https://reactome.org/PathwayBrowser/#/R-HSA-6802921 Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 30616 R-HSA-6802922 https://reactome.org/PathwayBrowser/#/R-HSA-6802922 Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS TAS Homo sapiens 30616 R-HSA-6802924 https://reactome.org/PathwayBrowser/#/R-HSA-6802924 RAF is phosphorylated downstream of oncogenic RAS TAS Homo sapiens 30616 R-HSA-6802926 https://reactome.org/PathwayBrowser/#/R-HSA-6802926 Mutant RAS:p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 30616 R-HSA-6802927 https://reactome.org/PathwayBrowser/#/R-HSA-6802927 BRAF and RAF fusion mutant dimers are phosphorylated TAS Homo sapiens 30616 R-HSA-6802933 https://reactome.org/PathwayBrowser/#/R-HSA-6802933 p-BRAF and RAF fusion dimers phosphorylate MAP2Ks TAS Homo sapiens 30616 R-HSA-6802935 https://reactome.org/PathwayBrowser/#/R-HSA-6802935 MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers TAS Homo sapiens 30616 R-HSA-6802941 https://reactome.org/PathwayBrowser/#/R-HSA-6802941 RAF is paradoxically phosphorylated downstream of kinase-inactive RAF TAS Homo sapiens 30616 R-HSA-6802943 https://reactome.org/PathwayBrowser/#/R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 30616 R-HSA-6802973 https://reactome.org/PathwayBrowser/#/R-HSA-6802973 PLK3 phosphorylates CDC25C TAS Homo sapiens 30616 R-HSA-6803545 https://reactome.org/PathwayBrowser/#/R-HSA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen TAS Homo sapiens 30616 R-HSA-6803771 https://reactome.org/PathwayBrowser/#/R-HSA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P TAS Homo sapiens 30616 R-HSA-6804266 https://reactome.org/PathwayBrowser/#/R-HSA-6804266 CHEK2 phosphorylates TTC5 TAS Homo sapiens 30616 R-HSA-6804276 https://reactome.org/PathwayBrowser/#/R-HSA-6804276 ATM phosphorylates TTC5 TAS Homo sapiens 30616 R-HSA-6804596 https://reactome.org/PathwayBrowser/#/R-HSA-6804596 APAF1:CYCS binds APIP TAS Homo sapiens 30616 R-HSA-6804955 https://reactome.org/PathwayBrowser/#/R-HSA-6804955 ATM phosphorylates MDM2 TAS Homo sapiens 30616 R-HSA-6805059 https://reactome.org/PathwayBrowser/#/R-HSA-6805059 CK2:FACT phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6805103 https://reactome.org/PathwayBrowser/#/R-HSA-6805103 AURKA phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6805109 https://reactome.org/PathwayBrowser/#/R-HSA-6805109 CDK2 phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6805126 https://reactome.org/PathwayBrowser/#/R-HSA-6805126 AURKB phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6805276 https://reactome.org/PathwayBrowser/#/R-HSA-6805276 CDK5 phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6805285 https://reactome.org/PathwayBrowser/#/R-HSA-6805285 PLK3 phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6805399 https://reactome.org/PathwayBrowser/#/R-HSA-6805399 TAF1 phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6805470 https://reactome.org/PathwayBrowser/#/R-HSA-6805470 AMPK phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6805479 https://reactome.org/PathwayBrowser/#/R-HSA-6805479 TP53RK phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-6805640 https://reactome.org/PathwayBrowser/#/R-HSA-6805640 AKT phosphorylates KAT6A TAS Homo sapiens 30616 R-HSA-6805785 https://reactome.org/PathwayBrowser/#/R-HSA-6805785 AKT phosphorylates PHF20 TAS Homo sapiens 30616 R-HSA-6806877 https://reactome.org/PathwayBrowser/#/R-HSA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs TAS Homo sapiens 30616 R-HSA-6806967 https://reactome.org/PathwayBrowser/#/R-HSA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH TAS Homo sapiens 30616 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 30616 R-HSA-6807868 https://reactome.org/PathwayBrowser/#/R-HSA-6807868 GBF1 stimulates ARF nucleotide exchange TAS Homo sapiens 30616 R-HSA-6809015 https://reactome.org/PathwayBrowser/#/R-HSA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi TAS Homo sapiens 30616 R-HSA-6810233 https://reactome.org/PathwayBrowser/#/R-HSA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter TAS Homo sapiens 30616 R-HSA-6811422 https://reactome.org/PathwayBrowser/#/R-HSA-6811422 NSF ATPase activity dissociates cis-SNARE at the ER TAS Homo sapiens 30616 R-HSA-6811454 https://reactome.org/PathwayBrowser/#/R-HSA-6811454 MAPKs phosphorylate PP2A TAS Homo sapiens 30616 R-HSA-6811522 https://reactome.org/PathwayBrowser/#/R-HSA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus TAS Homo sapiens 30616 R-HSA-6814120 https://reactome.org/PathwayBrowser/#/R-HSA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT TAS Homo sapiens 30616 R-HSA-6814124 https://reactome.org/PathwayBrowser/#/R-HSA-6814124 ATP binds G-protein beta associated TRiC/CCT TAS Homo sapiens 30616 R-HSA-6814409 https://reactome.org/PathwayBrowser/#/R-HSA-6814409 CK2 phosphorylates PDCL TAS Homo sapiens 30616 R-HSA-6814549 https://reactome.org/PathwayBrowser/#/R-HSA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding TAS Homo sapiens 30616 R-HSA-6814559 https://reactome.org/PathwayBrowser/#/R-HSA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine TAS Homo sapiens 30616 R-HSA-6814670 https://reactome.org/PathwayBrowser/#/R-HSA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation TAS Homo sapiens 30616 R-HSA-6814675 https://reactome.org/PathwayBrowser/#/R-HSA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN TAS Homo sapiens 30616 R-HSA-6814678 https://reactome.org/PathwayBrowser/#/R-HSA-6814678 ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN TAS Homo sapiens 30616 R-HSA-6814683 https://reactome.org/PathwayBrowser/#/R-HSA-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN TAS Homo sapiens 30616 R-HSA-68610 https://reactome.org/PathwayBrowser/#/R-HSA-68610 Formation of ORC(2-5) complex TAS Homo sapiens 30616 R-HSA-68944 https://reactome.org/PathwayBrowser/#/R-HSA-68944 Orc1 is phosphorylated by cyclin A/CDK2 TAS Homo sapiens 30616 R-HSA-68954 https://reactome.org/PathwayBrowser/#/R-HSA-68954 Mcm2-7 is phosphorylated by DDK TAS Homo sapiens 30616 R-HSA-69005 https://reactome.org/PathwayBrowser/#/R-HSA-69005 Cdc6 protein is phosphorylated by CDK TAS Homo sapiens 30616 R-HSA-69015 https://reactome.org/PathwayBrowser/#/R-HSA-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex TAS Homo sapiens 30616 R-HSA-69063 https://reactome.org/PathwayBrowser/#/R-HSA-69063 Loading of PCNA - Sliding Clamp Formation TAS Homo sapiens 30616 R-HSA-69195 https://reactome.org/PathwayBrowser/#/R-HSA-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 TAS Homo sapiens 30616 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 30616 R-HSA-69604 https://reactome.org/PathwayBrowser/#/R-HSA-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 TAS Homo sapiens 30616 R-HSA-69608 https://reactome.org/PathwayBrowser/#/R-HSA-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 TAS Homo sapiens 30616 R-HSA-69685 https://reactome.org/PathwayBrowser/#/R-HSA-69685 CHEK2 phosphorylates TP53 TAS Homo sapiens 30616 R-HSA-69754 https://reactome.org/PathwayBrowser/#/R-HSA-69754 Phosphorylation of proteins involved in G2/M transition by active Cyclin A1:Cdc2 complexes TAS Homo sapiens 30616 R-HSA-69756 https://reactome.org/PathwayBrowser/#/R-HSA-69756 Phosphorylation of proteins involved in G2/M transition by active Cyclin A2:Cdc2 complexes TAS Homo sapiens 30616 R-HSA-69891 https://reactome.org/PathwayBrowser/#/R-HSA-69891 Phosphorylation and activation of CHEK2 by ATM TAS Homo sapiens 30616 R-HSA-70333 https://reactome.org/PathwayBrowser/#/R-HSA-70333 KHK dimer phosphorylates Fru to Fru 1-P TAS Homo sapiens 30616 R-HSA-70349 https://reactome.org/PathwayBrowser/#/R-HSA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate TAS Homo sapiens 30616 R-HSA-70355 https://reactome.org/PathwayBrowser/#/R-HSA-70355 GALK1 phosphorylates Gal to Gal1P TAS Homo sapiens 30616 R-HSA-70420 https://reactome.org/PathwayBrowser/#/R-HSA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P TAS Homo sapiens 30616 R-HSA-70467 https://reactome.org/PathwayBrowser/#/R-HSA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP TAS Homo sapiens 30616 R-HSA-70486 https://reactome.org/PathwayBrowser/#/R-HSA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG TAS Homo sapiens 30616 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 30616 R-HSA-70555 https://reactome.org/PathwayBrowser/#/R-HSA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] TAS Homo sapiens 30616 R-HSA-70577 https://reactome.org/PathwayBrowser/#/R-HSA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA TAS Homo sapiens 30616 R-HSA-70599 https://reactome.org/PathwayBrowser/#/R-HSA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] TAS Homo sapiens 30616 R-HSA-70606 https://reactome.org/PathwayBrowser/#/R-HSA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] TAS Homo sapiens 30616 R-HSA-70773 https://reactome.org/PathwayBrowser/#/R-HSA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] TAS Homo sapiens 30616 R-HSA-70967 https://reactome.org/PathwayBrowser/#/R-HSA-70967 IDH3 complex decarboxylates isocitrate TAS Homo sapiens 30616 R-HSA-70997 https://reactome.org/PathwayBrowser/#/R-HSA-70997 SUCLG1/A2 cleaves succinyl-CoA TAS Homo sapiens 30616 R-HSA-71031 https://reactome.org/PathwayBrowser/#/R-HSA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate TAS Homo sapiens 30616 R-HSA-71401 https://reactome.org/PathwayBrowser/#/R-HSA-71401 OGDH dimer decarboxylates 2-OG TAS Homo sapiens 30616 R-HSA-71541 https://reactome.org/PathwayBrowser/#/R-HSA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP TAS Homo sapiens 30616 R-HSA-71588 https://reactome.org/PathwayBrowser/#/R-HSA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP TAS Homo sapiens 30616 R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 30616 R-HSA-71735 https://reactome.org/PathwayBrowser/#/R-HSA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] TAS Homo sapiens 30616 R-HSA-71802 https://reactome.org/PathwayBrowser/#/R-HSA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP TAS Homo sapiens 30616 R-HSA-71850 https://reactome.org/PathwayBrowser/#/R-HSA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP TAS Homo sapiens 30616 R-HSA-72180 https://reactome.org/PathwayBrowser/#/R-HSA-72180 Cleavage of mRNA at the 3'-end TAS Homo sapiens 30616 R-HSA-72185 https://reactome.org/PathwayBrowser/#/R-HSA-72185 mRNA polyadenylation TAS Homo sapiens 30616 R-HSA-72621 https://reactome.org/PathwayBrowser/#/R-HSA-72621 Ribosomal scanning TAS Homo sapiens 30616 R-HSA-72647 https://reactome.org/PathwayBrowser/#/R-HSA-72647 Cap-bound mRNA is activated by helicases TAS Homo sapiens 30616 R-HSA-727819 https://reactome.org/PathwayBrowser/#/R-HSA-727819 TAK1 phosphorylates MKK6 TAS Homo sapiens 30616 R-HSA-73548 https://reactome.org/PathwayBrowser/#/R-HSA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) TAS Homo sapiens 30616 R-HSA-73577 https://reactome.org/PathwayBrowser/#/R-HSA-73577 CAD hexamer transforms L-Gln to CAP TAS Homo sapiens 30616 R-HSA-73580 https://reactome.org/PathwayBrowser/#/R-HSA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate TAS Homo sapiens 30616 R-HSA-73598 https://reactome.org/PathwayBrowser/#/R-HSA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) TAS Homo sapiens 30616 R-HSA-73599 https://reactome.org/PathwayBrowser/#/R-HSA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] TAS Homo sapiens 30616 R-HSA-73632 https://reactome.org/PathwayBrowser/#/R-HSA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] TAS Homo sapiens 30616 R-HSA-73635 https://reactome.org/PathwayBrowser/#/R-HSA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] TAS Homo sapiens 30616 R-HSA-73647 https://reactome.org/PathwayBrowser/#/R-HSA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] TAS Homo sapiens 30616 R-HSA-73722 https://reactome.org/PathwayBrowser/#/R-HSA-73722 Phosphorylation of UBF-1:rDNA Promoter TAS Homo sapiens 30616 R-HSA-73788 https://reactome.org/PathwayBrowser/#/R-HSA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) TAS Homo sapiens 30616 R-HSA-73792 https://reactome.org/PathwayBrowser/#/R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate TAS Homo sapiens 30616 R-HSA-73805 https://reactome.org/PathwayBrowser/#/R-HSA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi TAS Homo sapiens 30616 R-HSA-73810 https://reactome.org/PathwayBrowser/#/R-HSA-73810 FGAM + ATP => AIR + ADP + Pi TAS Homo sapiens 30616 R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 30616 R-HSA-73814 https://reactome.org/PathwayBrowser/#/R-HSA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi TAS Homo sapiens 30616 R-HSA-74207 https://reactome.org/PathwayBrowser/#/R-HSA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) TAS Homo sapiens 30616 R-HSA-74220 https://reactome.org/PathwayBrowser/#/R-HSA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) TAS Homo sapiens 30616 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 30616 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 30616 R-HSA-74615 https://reactome.org/PathwayBrowser/#/R-HSA-74615 PRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP IEA Homo sapiens 30616 R-HSA-74711 https://reactome.org/PathwayBrowser/#/R-HSA-74711 Phosphorylation of IRS TAS Homo sapiens 30616 R-HSA-74715 https://reactome.org/PathwayBrowser/#/R-HSA-74715 Autophosphorylation of insulin receptor TAS Homo sapiens 30616 R-HSA-74742 https://reactome.org/PathwayBrowser/#/R-HSA-74742 Phosphorylation of SHC1 TAS Homo sapiens 30616 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 30616 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 30616 R-HSA-75010 https://reactome.org/PathwayBrowser/#/R-HSA-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 TAS Homo sapiens 30616 R-HSA-75028 https://reactome.org/PathwayBrowser/#/R-HSA-75028 Phosphorylation of Wee1 kinase by Chk1 IEA Homo sapiens 30616 R-HSA-751040 https://reactome.org/PathwayBrowser/#/R-HSA-751040 PKC phosphorylates G alpha (z) IEA Homo sapiens 30616 R-HSA-75125 https://reactome.org/PathwayBrowser/#/R-HSA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) TAS Homo sapiens 30616 R-HSA-75126 https://reactome.org/PathwayBrowser/#/R-HSA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] TAS Homo sapiens 30616 R-HSA-75809 https://reactome.org/PathwayBrowser/#/R-HSA-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 TAS Homo sapiens 30616 R-HSA-75820 https://reactome.org/PathwayBrowser/#/R-HSA-75820 Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta IEA Homo sapiens 30616 R-HSA-75848 https://reactome.org/PathwayBrowser/#/R-HSA-75848 ACLY tetramer transforms CIT to Ac-CoA TAS Homo sapiens 30616 R-HSA-75851 https://reactome.org/PathwayBrowser/#/R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 30616 R-HSA-75887 https://reactome.org/PathwayBrowser/#/R-HSA-75887 Conversion of Glycerol to Glycerol-3-phosphate TAS Homo sapiens 30616 R-HSA-75949 https://reactome.org/PathwayBrowser/#/R-HSA-75949 RNA Polymerase II Promoter Opening: First Transition TAS Homo sapiens 30616 R-HSA-77071 https://reactome.org/PathwayBrowser/#/R-HSA-77071 Phosphorylation (Ser5) of RNA pol II CTD TAS Homo sapiens 30616 R-HSA-844438 https://reactome.org/PathwayBrowser/#/R-HSA-844438 NLRP1 oligomerizes TAS Homo sapiens 30616 R-HSA-873918 https://reactome.org/PathwayBrowser/#/R-HSA-873918 Transphosphorylation of JAK1 TAS Homo sapiens 30616 R-HSA-873919 https://reactome.org/PathwayBrowser/#/R-HSA-873919 Phosphorylation of JAK2 TAS Homo sapiens 30616 R-HSA-873922 https://reactome.org/PathwayBrowser/#/R-HSA-873922 Phosphorylation of STAT1 by JAK kinases TAS Homo sapiens 30616 R-HSA-873924 https://reactome.org/PathwayBrowser/#/R-HSA-873924 Phosphorylation of IFNGR1 by JAK kinases TAS Homo sapiens 30616 R-HSA-877158 https://reactome.org/PathwayBrowser/#/R-HSA-877158 P2X7 forms oligomeric non-selective cation channels IEA Homo sapiens 30616 R-HSA-877178 https://reactome.org/PathwayBrowser/#/R-HSA-877178 ATP binds to P2X7 IEA Homo sapiens 30616 R-HSA-877187 https://reactome.org/PathwayBrowser/#/R-HSA-877187 P2X7 mediates loss of intracellular K+ TAS Homo sapiens 30616 R-HSA-877198 https://reactome.org/PathwayBrowser/#/R-HSA-877198 P2X7 mediates membrane pores that include pannexin-1 TAS Homo sapiens 30616 R-HSA-879222 https://reactome.org/PathwayBrowser/#/R-HSA-879222 MDP:NLRP1 binds ATP TAS Homo sapiens 30616 R-HSA-879907 https://reactome.org/PathwayBrowser/#/R-HSA-879907 Tyrosine kinases phosphorylate the receptor TAS Homo sapiens 30616 R-HSA-879909 https://reactome.org/PathwayBrowser/#/R-HSA-879909 Activation of STAT5a/b by JAK2 TAS Homo sapiens 30616 R-HSA-879910 https://reactome.org/PathwayBrowser/#/R-HSA-879910 JAK2 is phosphorylated, activated TAS Homo sapiens 30616 R-HSA-8847638 https://reactome.org/PathwayBrowser/#/R-HSA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane TAS Homo sapiens 30616 R-HSA-8847977 https://reactome.org/PathwayBrowser/#/R-HSA-8847977 FRK phosphorylates PTEN TAS Homo sapiens 30616 R-HSA-8848005 https://reactome.org/PathwayBrowser/#/R-HSA-8848005 ERBB2 promotes PTK6 autophosphorylation TAS Homo sapiens 30616 R-HSA-8848053 https://reactome.org/PathwayBrowser/#/R-HSA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol TAS Homo sapiens 30616 R-HSA-8848077 https://reactome.org/PathwayBrowser/#/R-HSA-8848077 PTK6 phosphorylates STAP2 TAS Homo sapiens 30616 R-HSA-8848124 https://reactome.org/PathwayBrowser/#/R-HSA-8848124 PTK6 phosphorylates STAT3 TAS Homo sapiens 30616 R-HSA-8848436 https://reactome.org/PathwayBrowser/#/R-HSA-8848436 PTK6 phosphorylates CDKN1B TAS Homo sapiens 30616 R-HSA-8848606 https://reactome.org/PathwayBrowser/#/R-HSA-8848606 PTK6 phosphorylates PXN TAS Homo sapiens 30616 R-HSA-8848726 https://reactome.org/PathwayBrowser/#/R-HSA-8848726 PTK6 phosphorylates BCAR1 TAS Homo sapiens 30616 R-HSA-8848758 https://reactome.org/PathwayBrowser/#/R-HSA-8848758 PTK6 phosphorylates AKT1 TAS Homo sapiens 30616 R-HSA-8848776 https://reactome.org/PathwayBrowser/#/R-HSA-8848776 PTK6 phosphorylates DOK1 TAS Homo sapiens 30616 R-HSA-8848818 https://reactome.org/PathwayBrowser/#/R-HSA-8848818 PTK6 phosphorylates CBL TAS Homo sapiens 30616 R-HSA-8848873 https://reactome.org/PathwayBrowser/#/R-HSA-8848873 PTK6 phosphorylates ARAP1 TAS Homo sapiens 30616 R-HSA-8848975 https://reactome.org/PathwayBrowser/#/R-HSA-8848975 PTK6 phosphorylates KHDRBS1 TAS Homo sapiens 30616 R-HSA-8849032 https://reactome.org/PathwayBrowser/#/R-HSA-8849032 PTK6 phosphorylates KHDRBS2 TAS Homo sapiens 30616 R-HSA-8849042 https://reactome.org/PathwayBrowser/#/R-HSA-8849042 PTK6 phosphorylates KHDRBS3 TAS Homo sapiens 30616 R-HSA-8849068 https://reactome.org/PathwayBrowser/#/R-HSA-8849068 PTK6 phosphorylates ARHGAP35 TAS Homo sapiens 30616 R-HSA-8849102 https://reactome.org/PathwayBrowser/#/R-HSA-8849102 SRMS phosphorylates PTK6 TAS Homo sapiens 30616 R-HSA-8849157 https://reactome.org/PathwayBrowser/#/R-HSA-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally TAS Homo sapiens 30616 R-HSA-8849353 https://reactome.org/PathwayBrowser/#/R-HSA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER TAS Homo sapiens 30616 R-HSA-8849463 https://reactome.org/PathwayBrowser/#/R-HSA-8849463 PTK6 phosphorylates SFPQ TAS Homo sapiens 30616 R-HSA-8850945 https://reactome.org/PathwayBrowser/#/R-HSA-8850945 Casein kinase II phosphorylates PTEN TAS Homo sapiens 30616 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 30616 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 30616 R-HSA-8851797 https://reactome.org/PathwayBrowser/#/R-HSA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated TAS Homo sapiens 30616 R-HSA-8851890 https://reactome.org/PathwayBrowser/#/R-HSA-8851890 MET phosphorylates SHC1-2 TAS Homo sapiens 30616 R-HSA-8851933 https://reactome.org/PathwayBrowser/#/R-HSA-8851933 MET phosphorylates GAB1 TAS Homo sapiens 30616 R-HSA-8852019 https://reactome.org/PathwayBrowser/#/R-HSA-8852019 MET bound PI3K generates PIP3 TAS Homo sapiens 30616 R-HSA-8852128 https://reactome.org/PathwayBrowser/#/R-HSA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm TAS Homo sapiens 30616 R-HSA-8852131 https://reactome.org/PathwayBrowser/#/R-HSA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus TAS Homo sapiens 30616 R-HSA-8852132 https://reactome.org/PathwayBrowser/#/R-HSA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol TAS Homo sapiens 30616 R-HSA-8852134 https://reactome.org/PathwayBrowser/#/R-HSA-8852134 UBA1 adenylates ubiquitin in the cytosol TAS Homo sapiens 30616 R-HSA-8852306 https://reactome.org/PathwayBrowser/#/R-HSA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends TAS Homo sapiens 30616 R-HSA-8852317 https://reactome.org/PathwayBrowser/#/R-HSA-8852317 PLK1 phosphorylates GTSE1 TAS Homo sapiens 30616 R-HSA-8852552 https://reactome.org/PathwayBrowser/#/R-HSA-8852552 MST1R autophosphorylates TAS Homo sapiens 30616 R-HSA-8853309 https://reactome.org/PathwayBrowser/#/R-HSA-8853309 Autocatalytic phosphorylation of FGFR3 fusions TAS Homo sapiens 30616 R-HSA-8853313 https://reactome.org/PathwayBrowser/#/R-HSA-8853313 FGFR2 fusions autophosphorylate TAS Homo sapiens 30616 R-HSA-8853325 https://reactome.org/PathwayBrowser/#/R-HSA-8853325 Plasma membrane FGFR1 fusions autophosphorylate TAS Homo sapiens 30616 R-HSA-8853419 https://reactome.org/PathwayBrowser/#/R-HSA-8853419 TPX2 promotes AURKA autophosphorylation TAS Homo sapiens 30616 R-HSA-8853444 https://reactome.org/PathwayBrowser/#/R-HSA-8853444 AURKA phosphorylates PHLDA1 TAS Homo sapiens 30616 R-HSA-8853774 https://reactome.org/PathwayBrowser/#/R-HSA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated TAS Homo sapiens 30616 R-HSA-8853792 https://reactome.org/PathwayBrowser/#/R-HSA-8853792 RET tyrosine phosphorylation TAS Homo sapiens 30616 R-HSA-8854908 https://reactome.org/PathwayBrowser/#/R-HSA-8854908 PKA phosphorylates RET:GDNF:GFRA dimer TAS Homo sapiens 30616 R-HSA-8855237 https://reactome.org/PathwayBrowser/#/R-HSA-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 TAS Homo sapiens 30616 R-HSA-8856813 https://reactome.org/PathwayBrowser/#/R-HSA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 TAS Homo sapiens 30616 R-HSA-8857555 https://reactome.org/PathwayBrowser/#/R-HSA-8857555 EGFR phosphorylates GPNMB TAS Homo sapiens 30616 R-HSA-8857577 https://reactome.org/PathwayBrowser/#/R-HSA-8857577 LINC01139 facilitates PTK6 autophosphorylation TAS Homo sapiens 30616 R-HSA-8857583 https://reactome.org/PathwayBrowser/#/R-HSA-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 TAS Homo sapiens 30616 R-HSA-8857925 https://reactome.org/PathwayBrowser/#/R-HSA-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 TAS Homo sapiens 30616 R-HSA-8863007 https://reactome.org/PathwayBrowser/#/R-HSA-8863007 p25-bound CDK5 phosphorylates CDC25B TAS Homo sapiens 30616 R-HSA-8863011 https://reactome.org/PathwayBrowser/#/R-HSA-8863011 p25-bound CDK5 phosphorylates CDC25C TAS Homo sapiens 30616 R-HSA-8863014 https://reactome.org/PathwayBrowser/#/R-HSA-8863014 p25-bound CDK5 phosphorylates CDC25A TAS Homo sapiens 30616 R-HSA-8863895 https://reactome.org/PathwayBrowser/#/R-HSA-8863895 IKKB phosphorylates SNAP23 TAS Homo sapiens 30616 R-HSA-8865050 https://reactome.org/PathwayBrowser/#/R-HSA-8865050 Ub-Cys625-UBA6 adenylates ubiquitin in the cytosol IEA Homo sapiens 30616 R-HSA-8865090 https://reactome.org/PathwayBrowser/#/R-HSA-8865090 UBA6 adenylates ubiquitin in the cytosol IEA Homo sapiens 30616 R-HSA-8865774 https://reactome.org/PathwayBrowser/#/R-HSA-8865774 TTLLs polyglutamylate tubulin TAS Homo sapiens 30616 R-HSA-8866268 https://reactome.org/PathwayBrowser/#/R-HSA-8866268 ADBRK1,2 phosphorylate AVPR2 TAS Homo sapiens 30616 R-HSA-8866405 https://reactome.org/PathwayBrowser/#/R-HSA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 30616 R-HSA-8866542 https://reactome.org/PathwayBrowser/#/R-HSA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol TAS Homo sapiens 30616 R-HSA-8866854 https://reactome.org/PathwayBrowser/#/R-HSA-8866854 VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol TAS Homo sapiens 30616 R-HSA-8867041 https://reactome.org/PathwayBrowser/#/R-HSA-8867041 EGFR phosphorylates EPS15 TAS Homo sapiens 30616 R-HSA-8867370 https://reactome.org/PathwayBrowser/#/R-HSA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin TAS Homo sapiens 30616 R-HSA-8868066 https://reactome.org/PathwayBrowser/#/R-HSA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 TAS Homo sapiens 30616 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 30616 R-HSA-8868118 https://reactome.org/PathwayBrowser/#/R-HSA-8868118 MAPK12 phosphorylates PTPN3 TAS Homo sapiens 30616 R-HSA-8868230 https://reactome.org/PathwayBrowser/#/R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery TAS Homo sapiens 30616 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 30616 R-HSA-8868260 https://reactome.org/PathwayBrowser/#/R-HSA-8868260 CDK5:p25 phosphorylates GOLGA2 IEA Homo sapiens 30616 R-HSA-8868340 https://reactome.org/PathwayBrowser/#/R-HSA-8868340 CDK5:p25 phosphorylates lamin B1 IEA Homo sapiens 30616 R-HSA-8868344 https://reactome.org/PathwayBrowser/#/R-HSA-8868344 CDK5:p25 phosphorylates lamin A IEA Homo sapiens 30616 R-HSA-8868567 https://reactome.org/PathwayBrowser/#/R-HSA-8868567 CDK5:p25 phosphorylates PRDX1 IEA Homo sapiens 30616 R-HSA-8868573 https://reactome.org/PathwayBrowser/#/R-HSA-8868573 CDK5:p25 phosphorylates PRDX2 IEA Homo sapiens 30616 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 30616 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 30616 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 30616 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 30616 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 30616 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 30616 R-HSA-8868666 https://reactome.org/PathwayBrowser/#/R-HSA-8868666 CDK5:p25 phosphorylates JUN IEA Homo sapiens 30616 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 30616 R-HSA-8869606 https://reactome.org/PathwayBrowser/#/R-HSA-8869606 NMRK1 phosphorylates NAR to yield NAMN TAS Homo sapiens 30616 R-HSA-8869607 https://reactome.org/PathwayBrowser/#/R-HSA-8869607 NMRK2 phosphorylates NAR to yield NAMN TAS Homo sapiens 30616 R-HSA-8869627 https://reactome.org/PathwayBrowser/#/R-HSA-8869627 NMRK2 phosphorylates NR to yield NMN TAS Homo sapiens 30616 R-HSA-8869633 https://reactome.org/PathwayBrowser/#/R-HSA-8869633 NMRK1 phosphorylates NR to yield NMN TAS Homo sapiens 30616 R-HSA-8870558 https://reactome.org/PathwayBrowser/#/R-HSA-8870558 CDK5:p25 phosphorylates FOXO3 IEA Homo sapiens 30616 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 30616 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 30616 R-HSA-8871373 https://reactome.org/PathwayBrowser/#/R-HSA-8871373 BMX phosphorylates RUFY1 TAS Homo sapiens 30616 R-HSA-8873929 https://reactome.org/PathwayBrowser/#/R-HSA-8873929 Casein kinase II phosphorylates STARD10 TAS Homo sapiens 30616 R-HSA-8874078 https://reactome.org/PathwayBrowser/#/R-HSA-8874078 PTK2 autophosphorylates TAS Homo sapiens 30616 R-HSA-8874080 https://reactome.org/PathwayBrowser/#/R-HSA-8874080 SRC phosphorylates PTK2 TAS Homo sapiens 30616 R-HSA-8874082 https://reactome.org/PathwayBrowser/#/R-HSA-8874082 MET phosphorylates PTK2 TAS Homo sapiens 30616 R-HSA-8875013 https://reactome.org/PathwayBrowser/#/R-HSA-8875013 ACSM3,ACSM6 ligate CoA to BUT IEA Homo sapiens 30616 R-HSA-8875071 https://reactome.org/PathwayBrowser/#/R-HSA-8875071 ACSS3 ligates CoA to CH3COO- TAS Homo sapiens 30616 R-HSA-8875077 https://reactome.org/PathwayBrowser/#/R-HSA-8875077 SLC27A3 ligates CoA-SH to VLCFA IEA Homo sapiens 30616 R-HSA-8875451 https://reactome.org/PathwayBrowser/#/R-HSA-8875451 MET phosphorylates CBL TAS Homo sapiens 30616 R-HSA-8875817 https://reactome.org/PathwayBrowser/#/R-HSA-8875817 MET phosphorylates STAT3 TAS Homo sapiens 30616 R-HSA-8876230 https://reactome.org/PathwayBrowser/#/R-HSA-8876230 InlB:MET dimer trans-autophophorylates TAS Homo sapiens 30616 R-HSA-8876246 https://reactome.org/PathwayBrowser/#/R-HSA-8876246 InlB-activated MET phosphorylates CBL IEA Homo sapiens 30616 R-HSA-8876446 https://reactome.org/PathwayBrowser/#/R-HSA-8876446 p-ULK1 phosphorylates DENND3 TAS Homo sapiens 30616 R-HSA-8876889 https://reactome.org/PathwayBrowser/#/R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 30616 R-HSA-8876948 https://reactome.org/PathwayBrowser/#/R-HSA-8876948 SRC phosphorylates InlA-bound CDH1 and CTNNB1 TAS Homo sapiens 30616 R-HSA-8877691 https://reactome.org/PathwayBrowser/#/R-HSA-8877691 MAP2K6 phosphorylates PIP4K2B TAS Homo sapiens 30616 R-HSA-8878050 https://reactome.org/PathwayBrowser/#/R-HSA-8878050 HIPK2 phosphorylates RUNX1 and EP300 TAS Homo sapiens 30616 R-HSA-8878054 https://reactome.org/PathwayBrowser/#/R-HSA-8878054 HIPK2 phosphorylates RUNX1 TAS Homo sapiens 30616 R-HSA-8931653 https://reactome.org/PathwayBrowser/#/R-HSA-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 TAS Homo sapiens 30616 R-HSA-8932284 https://reactome.org/PathwayBrowser/#/R-HSA-8932284 PKC phosphorylates NFE2L2 IEA Homo sapiens 30616 R-HSA-8932322 https://reactome.org/PathwayBrowser/#/R-HSA-8932322 CK2 phosphorylates NFE2L2 IEA Homo sapiens 30616 R-HSA-8933446 https://reactome.org/PathwayBrowser/#/R-HSA-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling TAS Homo sapiens 30616 R-HSA-8934446 https://reactome.org/PathwayBrowser/#/R-HSA-8934446 Activated PKC phosphorylates SHC1 TAS Homo sapiens 30616 R-HSA-8937728 https://reactome.org/PathwayBrowser/#/R-HSA-8937728 SRC phosphorylates RUNX1 IEA Homo sapiens 30616 R-HSA-8937807 https://reactome.org/PathwayBrowser/#/R-HSA-8937807 SRC phosphorylates RUNX3 TAS Homo sapiens 30616 R-HSA-8937844 https://reactome.org/PathwayBrowser/#/R-HSA-8937844 SRC,YES1 phosphorylate YAP1 IEA Homo sapiens 30616 R-HSA-8939203 https://reactome.org/PathwayBrowser/#/R-HSA-8939203 HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex TAS Homo sapiens 30616 R-HSA-8939204 https://reactome.org/PathwayBrowser/#/R-HSA-8939204 ESTG binds ESR1:chaperone complex TAS Homo sapiens 30616 R-HSA-8939959 https://reactome.org/PathwayBrowser/#/R-HSA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ TAS Homo sapiens 30616 R-HSA-8939963 https://reactome.org/PathwayBrowser/#/R-HSA-8939963 Activated AKT phosphorylates RUNX2 IEA Homo sapiens 30616 R-HSA-8940100 https://reactome.org/PathwayBrowser/#/R-HSA-8940100 CDK1 phosphorylates VCPIP1 TAS Homo sapiens 30616 R-HSA-8942575 https://reactome.org/PathwayBrowser/#/R-HSA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG TAS Homo sapiens 30616 R-HSA-8942607 https://reactome.org/PathwayBrowser/#/R-HSA-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes TAS Homo sapiens 30616 R-HSA-8942836 https://reactome.org/PathwayBrowser/#/R-HSA-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 TAS Homo sapiens 30616 R-HSA-8944454 https://reactome.org/PathwayBrowser/#/R-HSA-8944454 mTORC1 phosphorylates MAF1 TAS Homo sapiens 30616 R-HSA-8948039 https://reactome.org/PathwayBrowser/#/R-HSA-8948039 FUNDC1 is phosphorylated by CK2 TAS Homo sapiens 30616 R-HSA-8948143 https://reactome.org/PathwayBrowser/#/R-HSA-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 TAS Homo sapiens 30616 R-HSA-8948146 https://reactome.org/PathwayBrowser/#/R-HSA-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 TAS Homo sapiens 30616 R-HSA-8948757 https://reactome.org/PathwayBrowser/#/R-HSA-8948757 AKT phosphorylates MKRN1 TAS Homo sapiens 30616 R-HSA-8950269 https://reactome.org/PathwayBrowser/#/R-HSA-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor TAS Homo sapiens 30616 R-HSA-8950340 https://reactome.org/PathwayBrowser/#/R-HSA-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation TAS Homo sapiens 30616 R-HSA-8950354 https://reactome.org/PathwayBrowser/#/R-HSA-8950354 STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interaction IEA Homo sapiens 30616 R-HSA-8950364 https://reactome.org/PathwayBrowser/#/R-HSA-8950364 IL23R in IL23:IL23 receptor complex is phosphorylated IEA Homo sapiens 30616 R-HSA-8950405 https://reactome.org/PathwayBrowser/#/R-HSA-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated TAS Homo sapiens 30616 R-HSA-8950423 https://reactome.org/PathwayBrowser/#/R-HSA-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated TAS Homo sapiens 30616 R-HSA-8950453 https://reactome.org/PathwayBrowser/#/R-HSA-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 TAS Homo sapiens 30616 R-HSA-8950485 https://reactome.org/PathwayBrowser/#/R-HSA-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction TAS Homo sapiens 30616 R-HSA-8950537 https://reactome.org/PathwayBrowser/#/R-HSA-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated TAS Homo sapiens 30616 R-HSA-8950591 https://reactome.org/PathwayBrowser/#/R-HSA-8950591 JAK2, TYK2 in IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 are phosphorylated IEA Homo sapiens 30616 R-HSA-8950757 https://reactome.org/PathwayBrowser/#/R-HSA-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated TAS Homo sapiens 30616 R-HSA-8951648 https://reactome.org/PathwayBrowser/#/R-HSA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 TAS Homo sapiens 30616 R-HSA-8951656 https://reactome.org/PathwayBrowser/#/R-HSA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 TAS Homo sapiens 30616 R-HSA-8952289 https://reactome.org/PathwayBrowser/#/R-HSA-8952289 FAM20C phosphorylates FAM20C substrates TAS Homo sapiens 30616 R-HSA-8954327 https://reactome.org/PathwayBrowser/#/R-HSA-8954327 UCKL1 phosphorylates urindine, cytidine TAS Homo sapiens 30616 R-HSA-8955030 https://reactome.org/PathwayBrowser/#/R-HSA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ TAS Homo sapiens 30616 R-HSA-8955706 https://reactome.org/PathwayBrowser/#/R-HSA-8955706 TTL ligates L-Tyr to the carboxy terminus of detyr-alpha tubulin:beta tubulin IEA Homo sapiens 30616 R-HSA-8955844 https://reactome.org/PathwayBrowser/#/R-HSA-8955844 RBKS phosphorylates ribose to R5P TAS Homo sapiens 30616 R-HSA-8955869 https://reactome.org/PathwayBrowser/#/R-HSA-8955869 Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin IEA Homo sapiens 30616 R-HSA-8956659 https://reactome.org/PathwayBrowser/#/R-HSA-8956659 ABL1 phosphorylates YAP1 TAS Homo sapiens 30616 R-HSA-8959510 https://reactome.org/PathwayBrowser/#/R-HSA-8959510 SEPHS2 phosphorylates H2Se to form SELP TAS Homo sapiens 30616 R-HSA-8959719 https://reactome.org/PathwayBrowser/#/R-HSA-8959719 SHPK phosphorylates Sedo to Sedo7P TAS Homo sapiens 30616 R-HSA-8964242 https://reactome.org/PathwayBrowser/#/R-HSA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC TAS Homo sapiens 30616 R-HSA-8964252 https://reactome.org/PathwayBrowser/#/R-HSA-8964252 G alpha (s):GTP:SRC catalyzes SRC to p-Y419-SRC TAS Homo sapiens 30616 R-HSA-8982163 https://reactome.org/PathwayBrowser/#/R-HSA-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 TAS Homo sapiens 30616 R-HSA-8983059 https://reactome.org/PathwayBrowser/#/R-HSA-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex TAS Homo sapiens 30616 R-HSA-8983063 https://reactome.org/PathwayBrowser/#/R-HSA-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated TAS Homo sapiens 30616 R-HSA-8983300 https://reactome.org/PathwayBrowser/#/R-HSA-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 TAS Homo sapiens 30616 R-HSA-8983309 https://reactome.org/PathwayBrowser/#/R-HSA-8983309 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates SHC1 IEA Homo sapiens 30616 R-HSA-8983371 https://reactome.org/PathwayBrowser/#/R-HSA-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 TAS Homo sapiens 30616 R-HSA-8983424 https://reactome.org/PathwayBrowser/#/R-HSA-8983424 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:GAB2 phosphorylates GAB2 IEA Homo sapiens 30616 R-HSA-8983680 https://reactome.org/PathwayBrowser/#/R-HSA-8983680 OAS1 produces oligoadenylates TAS Homo sapiens 30616 R-HSA-8983834 https://reactome.org/PathwayBrowser/#/R-HSA-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated TAS Homo sapiens 30616 R-HSA-8983835 https://reactome.org/PathwayBrowser/#/R-HSA-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 TAS Homo sapiens 30616 R-HSA-8983870 https://reactome.org/PathwayBrowser/#/R-HSA-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated TAS Homo sapiens 30616 R-HSA-8983872 https://reactome.org/PathwayBrowser/#/R-HSA-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 TAS Homo sapiens 30616 R-HSA-8984012 https://reactome.org/PathwayBrowser/#/R-HSA-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated TAS Homo sapiens 30616 R-HSA-8984014 https://reactome.org/PathwayBrowser/#/R-HSA-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 TAS Homo sapiens 30616 R-HSA-8985091 https://reactome.org/PathwayBrowser/#/R-HSA-8985091 OAS3 produces oligoadenylates TAS Homo sapiens 30616 R-HSA-8985104 https://reactome.org/PathwayBrowser/#/R-HSA-8985104 OAS2 produces oligoadenylates TAS Homo sapiens 30616 R-HSA-8985123 https://reactome.org/PathwayBrowser/#/R-HSA-8985123 RNASEL binds 2'-5' oligoadenylate TAS Homo sapiens 30616 R-HSA-8985914 https://reactome.org/PathwayBrowser/#/R-HSA-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 TAS Homo sapiens 30616 R-HSA-8985973 https://reactome.org/PathwayBrowser/#/R-HSA-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 TAS Homo sapiens 30616 R-HSA-8985988 https://reactome.org/PathwayBrowser/#/R-HSA-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 TAS Homo sapiens 30616 R-HSA-8986937 https://reactome.org/PathwayBrowser/#/R-HSA-8986937 MECP2 is phosphorylated at T308 IEA Homo sapiens 30616 R-HSA-8986985 https://reactome.org/PathwayBrowser/#/R-HSA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 TAS Homo sapiens 30616 R-HSA-8986994 https://reactome.org/PathwayBrowser/#/R-HSA-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 TAS Homo sapiens 30616 R-HSA-8986995 https://reactome.org/PathwayBrowser/#/R-HSA-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA TAS Homo sapiens 30616 R-HSA-8987012 https://reactome.org/PathwayBrowser/#/R-HSA-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 TAS Homo sapiens 30616 R-HSA-8987040 https://reactome.org/PathwayBrowser/#/R-HSA-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 TAS Homo sapiens 30616 R-HSA-8987042 https://reactome.org/PathwayBrowser/#/R-HSA-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 TAS Homo sapiens 30616 R-HSA-8987070 https://reactome.org/PathwayBrowser/#/R-HSA-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 TAS Homo sapiens 30616 R-HSA-8987084 https://reactome.org/PathwayBrowser/#/R-HSA-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 TAS Homo sapiens 30616 R-HSA-8987096 https://reactome.org/PathwayBrowser/#/R-HSA-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 TAS Homo sapiens 30616 R-HSA-8987129 https://reactome.org/PathwayBrowser/#/R-HSA-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated TAS Homo sapiens 30616 R-HSA-8987141 https://reactome.org/PathwayBrowser/#/R-HSA-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 TAS Homo sapiens 30616 R-HSA-8987150 https://reactome.org/PathwayBrowser/#/R-HSA-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 TAS Homo sapiens 30616 R-HSA-8987179 https://reactome.org/PathwayBrowser/#/R-HSA-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 TAS Homo sapiens 30616 R-HSA-8987202 https://reactome.org/PathwayBrowser/#/R-HSA-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 TAS Homo sapiens 30616 R-HSA-8987255 https://reactome.org/PathwayBrowser/#/R-HSA-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 TAS Homo sapiens 30616 R-HSA-9005561 https://reactome.org/PathwayBrowser/#/R-HSA-9005561 Active PKA, CaMK IV do not phosphorylate MECP2 mutants R306C,(R306H) at T308 IEA Homo sapiens 30616 R-HSA-9006323 https://reactome.org/PathwayBrowser/#/R-HSA-9006323 Phospho-JAK2 phosphorylates EPOR IEA Homo sapiens 30616 R-HSA-9006332 https://reactome.org/PathwayBrowser/#/R-HSA-9006332 JAK2 transphosphorylates and is activated in response to Erythropoietin IEA Homo sapiens 30616 R-HSA-9006850 https://reactome.org/PathwayBrowser/#/R-HSA-9006850 IL21 receptor JAK phosphorylation TAS Homo sapiens 30616 R-HSA-9006870 https://reactome.org/PathwayBrowser/#/R-HSA-9006870 IL21 receptor STAT phosphorylation TAS Homo sapiens 30616 R-HSA-9006992 https://reactome.org/PathwayBrowser/#/R-HSA-9006992 MECP2 is phosphorylated at S423 IEA Homo sapiens 30616 R-HSA-9007539 https://reactome.org/PathwayBrowser/#/R-HSA-9007539 CHEK1 phosphorylates E2F6 TAS Homo sapiens 30616 R-HSA-9008043 https://reactome.org/PathwayBrowser/#/R-HSA-9008043 MAPK8 phosphorylation TAS Homo sapiens 30616 R-HSA-9008412 https://reactome.org/PathwayBrowser/#/R-HSA-9008412 CDK4 phosphorylates RUNX2 TAS Homo sapiens 30616 R-HSA-9008480 https://reactome.org/PathwayBrowser/#/R-HSA-9008480 GSK3B phosphorylates RUNX2 IEA Homo sapiens 30616 R-HSA-9008684 https://reactome.org/PathwayBrowser/#/R-HSA-9008684 TBK1 phosphorylation TAS Homo sapiens 30616 R-HSA-9009072 https://reactome.org/PathwayBrowser/#/R-HSA-9009072 STAT3 phosphorylation TAS Homo sapiens 30616 R-HSA-9009208 https://reactome.org/PathwayBrowser/#/R-HSA-9009208 Activated ERKs phosphorylate RUNX2 IEA Homo sapiens 30616 R-HSA-9009282 https://reactome.org/PathwayBrowser/#/R-HSA-9009282 CDK1 phosphorylates RUNX2 TAS Homo sapiens 30616 R-HSA-9009700 https://reactome.org/PathwayBrowser/#/R-HSA-9009700 IL2RB and IL2RG are phosphorylated IEA Homo sapiens 30616 R-HSA-9009936 https://reactome.org/PathwayBrowser/#/R-HSA-9009936 RNASEL cleaves cellular ssRNA TAS Homo sapiens 30616 R-HSA-9009941 https://reactome.org/PathwayBrowser/#/R-HSA-9009941 RNASEL cleaves viral ssRNA TAS Homo sapiens 30616 R-HSA-9009950 https://reactome.org/PathwayBrowser/#/R-HSA-9009950 PDE12 cleaves 2'-5' oligoadenylates TAS Homo sapiens 30616 R-HSA-9010681 https://reactome.org/PathwayBrowser/#/R-HSA-9010681 PKC phosphorylates ROBO3.1 TAS Homo sapiens 30616 R-HSA-9011241 https://reactome.org/PathwayBrowser/#/R-HSA-9011241 SRC phosphorylates ROBO3.1 in response to NTN1 IEA Homo sapiens 30616 R-HSA-9012268 https://reactome.org/PathwayBrowser/#/R-HSA-9012268 ME2 tetramer decarboxylates MAL to PYR TAS Homo sapiens 30616 R-HSA-9012319 https://reactome.org/PathwayBrowser/#/R-HSA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD TAS Homo sapiens 30616 R-HSA-9012650 https://reactome.org/PathwayBrowser/#/R-HSA-9012650 JAK2 and LYN phosphorylate STAT5 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 IEA Homo sapiens 30616 R-HSA-9013978 https://reactome.org/PathwayBrowser/#/R-HSA-9013978 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex TAS Homo sapiens 30616 R-HSA-9014741 https://reactome.org/PathwayBrowser/#/R-HSA-9014741 PXLP-K56-SRR dimer deaminates D-Ser TAS Homo sapiens 30616 R-HSA-9014766 https://reactome.org/PathwayBrowser/#/R-HSA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser TAS Homo sapiens 30616 R-HSA-9018572 https://reactome.org/PathwayBrowser/#/R-HSA-9018572 EGFR phosphorylates NOTCH3 TAS Homo sapiens 30616 R-HSA-9021357 https://reactome.org/PathwayBrowser/#/R-HSA-9021357 PRKCI phosphorylates ELF3 TAS Homo sapiens 30616 R-HSA-9021609 https://reactome.org/PathwayBrowser/#/R-HSA-9021609 ESR-associated SRC autophosphorylates TAS Homo sapiens 30616 R-HSA-9021627 https://reactome.org/PathwayBrowser/#/R-HSA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-9022314 https://reactome.org/PathwayBrowser/#/R-HSA-9022314 HIPK2 phosphorylates MECP2 TAS Homo sapiens 30616 R-HSA-9023132 https://reactome.org/PathwayBrowser/#/R-HSA-9023132 AURKB phosphorylates MECP2 at S423 IEA Homo sapiens 30616 R-HSA-9024726 https://reactome.org/PathwayBrowser/#/R-HSA-9024726 LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1 IEA Homo sapiens 30616 R-HSA-9026464 https://reactome.org/PathwayBrowser/#/R-HSA-9026464 BDNF-bound NTRK2 dimers trans-autophosphorylate IEA Homo sapiens 30616 R-HSA-9026502 https://reactome.org/PathwayBrowser/#/R-HSA-9026502 NTF3-bound NTRK2 dimers trans-autophosphorylate IEA Homo sapiens 30616 R-HSA-9026510 https://reactome.org/PathwayBrowser/#/R-HSA-9026510 NTF4-bound NTRK2 dimers trans-autophosphorylate IEA Homo sapiens 30616 R-HSA-9026579 https://reactome.org/PathwayBrowser/#/R-HSA-9026579 NTRK2 phosphorylates PLCG1 IEA Homo sapiens 30616 R-HSA-9026890 https://reactome.org/PathwayBrowser/#/R-HSA-9026890 NTRK2 phosphorylates SHC1 IEA Homo sapiens 30616 R-HSA-9027272 https://reactome.org/PathwayBrowser/#/R-HSA-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 TAS Homo sapiens 30616 R-HSA-9027273 https://reactome.org/PathwayBrowser/#/R-HSA-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 TAS Homo sapiens 30616 R-HSA-9027425 https://reactome.org/PathwayBrowser/#/R-HSA-9027425 LYN phosphorylates PLCG1,2 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:PLCG1,2 IEA Homo sapiens 30616 R-HSA-9028519 https://reactome.org/PathwayBrowser/#/R-HSA-9028519 NTRK2-activated PI3K generates PIP3 IEA Homo sapiens 30616 R-HSA-9028728 https://reactome.org/PathwayBrowser/#/R-HSA-9028728 NTRK2 phosphorylates FRS2 IEA Homo sapiens 30616 R-HSA-9029151 https://reactome.org/PathwayBrowser/#/R-HSA-9029151 JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1 IEA Homo sapiens 30616 R-HSA-9029155 https://reactome.org/PathwayBrowser/#/R-HSA-9029155 JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1 IEA Homo sapiens 30616 R-HSA-9032426 https://reactome.org/PathwayBrowser/#/R-HSA-9032426 NTRK2 phosphorylates FRS3 IEA Homo sapiens 30616 R-HSA-9032532 https://reactome.org/PathwayBrowser/#/R-HSA-9032532 NTRK2-bound FYN autophosphorylates IEA Homo sapiens 30616 R-HSA-9032601 https://reactome.org/PathwayBrowser/#/R-HSA-9032601 FYN-mediated phosphorylation of GRIN2B IEA Homo sapiens 30616 R-HSA-9032751 https://reactome.org/PathwayBrowser/#/R-HSA-9032751 Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3 TAS Homo sapiens 30616 R-HSA-9032854 https://reactome.org/PathwayBrowser/#/R-HSA-9032854 NTRK2 phosphorylates CDK5 IEA Homo sapiens 30616 R-HSA-9032863 https://reactome.org/PathwayBrowser/#/R-HSA-9032863 CDK5 phosphorylates NTRK2 IEA Homo sapiens 30616 R-HSA-9033284 https://reactome.org/PathwayBrowser/#/R-HSA-9033284 NTRK2 promotes TIAM1 phosphorylation IEA Homo sapiens 30616 R-HSA-9033499 https://reactome.org/PathwayBrowser/#/R-HSA-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol TAS Homo sapiens 30616 R-HSA-9033505 https://reactome.org/PathwayBrowser/#/R-HSA-9033505 PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12 IEA Homo sapiens 30616 R-HSA-9034714 https://reactome.org/PathwayBrowser/#/R-HSA-9034714 NTRK3 dimers trans-autophosphorylate TAS Homo sapiens 30616 R-HSA-9034814 https://reactome.org/PathwayBrowser/#/R-HSA-9034814 NTRK3 phosphorylates PLCG1 IEA Homo sapiens 30616 R-HSA-9034875 https://reactome.org/PathwayBrowser/#/R-HSA-9034875 NTRK3 phosphorylates SHC1 IEA Homo sapiens 30616 R-HSA-9035987 https://reactome.org/PathwayBrowser/#/R-HSA-9035987 Defective HLCS does not biotinylate 6xMCCC1:6xMCCC2 TAS Homo sapiens 30616 R-HSA-9035988 https://reactome.org/PathwayBrowser/#/R-HSA-9035988 Defective HLCS does not biotinylate PC:Mn2+ TAS Homo sapiens 30616 R-HSA-9035990 https://reactome.org/PathwayBrowser/#/R-HSA-9035990 Defective HLCS does not biotinylate 6x(PCCA:PCCB) TAS Homo sapiens 30616 R-HSA-9037040 https://reactome.org/PathwayBrowser/#/R-HSA-9037040 SRC,FYN phosphorylate NTRK2 IEA Homo sapiens 30616 R-HSA-9038161 https://reactome.org/PathwayBrowser/#/R-HSA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG TAS Homo sapiens 30616 R-HSA-909552 https://reactome.org/PathwayBrowser/#/R-HSA-909552 Phosphorylation of STAT1 at Ser727 TAS Homo sapiens 30616 R-HSA-909718 https://reactome.org/PathwayBrowser/#/R-HSA-909718 Formation of p-STAT1 homodimer TAS Homo sapiens 30616 R-HSA-909726 https://reactome.org/PathwayBrowser/#/R-HSA-909726 Phosphorylation of STAT1 TAS Homo sapiens 30616 R-HSA-909729 https://reactome.org/PathwayBrowser/#/R-HSA-909729 Activation of JAK kinases TAS Homo sapiens 30616 R-HSA-909730 https://reactome.org/PathwayBrowser/#/R-HSA-909730 Phosphorylation of INFAR1 by TYK2 TAS Homo sapiens 30616 R-HSA-909732 https://reactome.org/PathwayBrowser/#/R-HSA-909732 Phosphorylation of STAT2 TAS Homo sapiens 30616 R-HSA-912470 https://reactome.org/PathwayBrowser/#/R-HSA-912470 ATR phosphorylates Histone H2A.X at unsynapsed regions IEA Homo sapiens 30616 R-HSA-912527 https://reactome.org/PathwayBrowser/#/R-HSA-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 TAS Homo sapiens 30616 R-HSA-912629 https://reactome.org/PathwayBrowser/#/R-HSA-912629 CBL is tyrosine phosphorylated IEA Homo sapiens 30616 R-HSA-913996 https://reactome.org/PathwayBrowser/#/R-HSA-913996 PKA/PKG phosphorylate Rap1GAP2 TAS Homo sapiens 30616 R-HSA-917693 https://reactome.org/PathwayBrowser/#/R-HSA-917693 ESCRT Disassembly TAS Homo sapiens 30616 R-HSA-917841 https://reactome.org/PathwayBrowser/#/R-HSA-917841 Acidification of Tf:TfR1 containing endosome TAS Homo sapiens 30616 R-HSA-917979 https://reactome.org/PathwayBrowser/#/R-HSA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-918224 https://reactome.org/PathwayBrowser/#/R-HSA-918224 DDX58 is K63 polyubiquitinated TAS Homo sapiens 30616 R-HSA-918225 https://reactome.org/PathwayBrowser/#/R-HSA-918225 TBK1/IKK epsilon complex interacts with MAVS bound TRAF3 TAS Homo sapiens 30616 R-HSA-918227 https://reactome.org/PathwayBrowser/#/R-HSA-918227 Recruitment of TRAF3 to MAVS TAS Homo sapiens 30616 R-HSA-918229 https://reactome.org/PathwayBrowser/#/R-HSA-918229 Phosphorylation and release of IRF3/IRF7 TAS Homo sapiens 30616 R-HSA-918230 https://reactome.org/PathwayBrowser/#/R-HSA-918230 Recruitment of TRAF6/TRAF2 to IPS-1 TAS Homo sapiens 30616 R-HSA-918232 https://reactome.org/PathwayBrowser/#/R-HSA-918232 Recruitment of IRF3,IRF7 TAS Homo sapiens 30616 R-HSA-927889 https://reactome.org/PathwayBrowser/#/R-HSA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) TAS Homo sapiens 30616 R-HSA-933523 https://reactome.org/PathwayBrowser/#/R-HSA-933523 Dimerzation of procaspase-8, procaspase-10 TAS Homo sapiens 30616 R-HSA-933525 https://reactome.org/PathwayBrowser/#/R-HSA-933525 Phosphorylation and release of IRF7 TAS Homo sapiens 30616 R-HSA-933526 https://reactome.org/PathwayBrowser/#/R-HSA-933526 Recruitment of caspase-8 and -10 to FADD complex TAS Homo sapiens 30616 R-HSA-933527 https://reactome.org/PathwayBrowser/#/R-HSA-933527 Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6 TAS Homo sapiens 30616 R-HSA-933528 https://reactome.org/PathwayBrowser/#/R-HSA-933528 Interaction of MEKK1 with TRAF6 IEA Homo sapiens 30616 R-HSA-933530 https://reactome.org/PathwayBrowser/#/R-HSA-933530 Activation of IKK by MEKK1 TAS Homo sapiens 30616 R-HSA-933532 https://reactome.org/PathwayBrowser/#/R-HSA-933532 Processing of caspases TAS Homo sapiens 30616 R-HSA-933537 https://reactome.org/PathwayBrowser/#/R-HSA-933537 Recruitment of TANK to TRAF6 TAS Homo sapiens 30616 R-HSA-933538 https://reactome.org/PathwayBrowser/#/R-HSA-933538 Recruitment of IRF7 to TRAF6 TAS Homo sapiens 30616 R-HSA-933539 https://reactome.org/PathwayBrowser/#/R-HSA-933539 Recruitment of IKK complex TAS Homo sapiens 30616 R-HSA-934559 https://reactome.org/PathwayBrowser/#/R-HSA-934559 SPRY2 is phosphorylated by phosphorylated MNK1 TAS Homo sapiens 30616 R-HSA-936378 https://reactome.org/PathwayBrowser/#/R-HSA-936378 Inhibition of DDX58/IFIH1 signaling by ATG5:ATG12:MAVS IEA Homo sapiens 30616 R-HSA-936381 https://reactome.org/PathwayBrowser/#/R-HSA-936381 OTUD5 deubiquitinates TRAF3 TAS Homo sapiens 30616 R-HSA-936475 https://reactome.org/PathwayBrowser/#/R-HSA-936475 Negative regulation of DDX58/IFIH1 signaling by RNF216 TAS Homo sapiens 30616 R-HSA-936802 https://reactome.org/PathwayBrowser/#/R-HSA-936802 ATP7A transports cytosolic Cu2+ to extracellular region TAS Homo sapiens 30616 R-HSA-936883 https://reactome.org/PathwayBrowser/#/R-HSA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen TAS Homo sapiens 30616 R-HSA-936895 https://reactome.org/PathwayBrowser/#/R-HSA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen TAS Homo sapiens 30616 R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 30616 R-HSA-936951 https://reactome.org/PathwayBrowser/#/R-HSA-936951 Activation of TAK1 complex bound to activated TLR4 complex TAS Homo sapiens 30616 R-HSA-936991 https://reactome.org/PathwayBrowser/#/R-HSA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 TAS Homo sapiens 30616 R-HSA-937022 https://reactome.org/PathwayBrowser/#/R-HSA-937022 IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP TAS Homo sapiens 30616 R-HSA-937034 https://reactome.org/PathwayBrowser/#/R-HSA-937034 IRAK1 phosphorylates Pellino TAS Homo sapiens 30616 R-HSA-937059 https://reactome.org/PathwayBrowser/#/R-HSA-937059 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex TAS Homo sapiens 30616 R-HSA-937311 https://reactome.org/PathwayBrowser/#/R-HSA-937311 ATP12A:ATP4B exchanges K+ for H+ TAS Homo sapiens 30616 R-HSA-937343 https://reactome.org/PathwayBrowser/#/R-HSA-937343 NLRC5 interacts with DDX58/IFIH1 TAS Homo sapiens 30616 R-HSA-939763 https://reactome.org/PathwayBrowser/#/R-HSA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane TAS Homo sapiens 30616 R-HSA-947531 https://reactome.org/PathwayBrowser/#/R-HSA-947531 Molybdenum ion transfer onto molybdopterin TAS Homo sapiens 30616 R-HSA-947538 https://reactome.org/PathwayBrowser/#/R-HSA-947538 Transfer of sulfur from MOCS3-S-S onto MOCS2A TAS Homo sapiens 30616 R-HSA-947591 https://reactome.org/PathwayBrowser/#/R-HSA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane TAS Homo sapiens 30616 R-HSA-9603420 https://reactome.org/PathwayBrowser/#/R-HSA-9603420 Activated NTRK3 promotes SRC autophosphorylation TAS Homo sapiens 30616 R-HSA-9603445 https://reactome.org/PathwayBrowser/#/R-HSA-9603445 Activated NTRK3 stimulates PI3K activity IEA Homo sapiens 30616 R-HSA-9604328 https://reactome.org/PathwayBrowser/#/R-HSA-9604328 AKT1 phosphorylates NOTCH4 TAS Homo sapiens 30616 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 30616 R-HSA-9606159 https://reactome.org/PathwayBrowser/#/R-HSA-9606159 BTK autophosphorylates IEA Homo sapiens 30616 R-HSA-9606162 https://reactome.org/PathwayBrowser/#/R-HSA-9606162 Phosphorylated BTK phosphorylates PLCG2 IEA Homo sapiens 30616 R-HSA-9606163 https://reactome.org/PathwayBrowser/#/R-HSA-9606163 p-SYK and LYN phosphorylate BTK IEA Homo sapiens 30616 R-HSA-9606622 https://reactome.org/PathwayBrowser/#/R-HSA-9606622 GAB2 in Active FLT3:GRB2:GAB2 is phosphorylated IEA Homo sapiens 30616 R-HSA-9606883 https://reactome.org/PathwayBrowser/#/R-HSA-9606883 CD19 is phosphorylated IEA Homo sapiens 30616 R-HSA-9606884 https://reactome.org/PathwayBrowser/#/R-HSA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated TAS Homo sapiens 30616 R-HSA-9609860 https://reactome.org/PathwayBrowser/#/R-HSA-9609860 Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP IEA Homo sapiens 30616 R-HSA-9609917 https://reactome.org/PathwayBrowser/#/R-HSA-9609917 Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane IEA Homo sapiens 30616 R-HSA-9610153 https://reactome.org/PathwayBrowser/#/R-HSA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF TAS Homo sapiens 30616 R-HSA-9610156 https://reactome.org/PathwayBrowser/#/R-HSA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF TAS Homo sapiens 30616 R-HSA-9610163 https://reactome.org/PathwayBrowser/#/R-HSA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF TAS Homo sapiens 30616 R-HSA-9610442 https://reactome.org/PathwayBrowser/#/R-HSA-9610442 Tail-anchored protein:SGTA dimer binds BAG6:GET4:UBL4A and ASNA1:ATP IEA Homo sapiens 30616 R-HSA-9610627 https://reactome.org/PathwayBrowser/#/R-HSA-9610627 KIF17 transports GluN1:GluN2B (GRIN1:GRIN2B) NMDA receptors to the plasma membrane IEA Homo sapiens 30616 R-HSA-9612085 https://reactome.org/PathwayBrowser/#/R-HSA-9612085 SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs IEA Homo sapiens 30616 R-HSA-9612501 https://reactome.org/PathwayBrowser/#/R-HSA-9612501 SGK phosphorylates CREB1 TAS Homo sapiens 30616 R-HSA-9612509 https://reactome.org/PathwayBrowser/#/R-HSA-9612509 SGK phosphorylates SRF TAS Homo sapiens 30616 R-HSA-9612980 https://reactome.org/PathwayBrowser/#/R-HSA-9612980 BRAF in Rap1-GTP complex:BRAF complex autophosphorylates IEA Homo sapiens 30616 R-HSA-9612996 https://reactome.org/PathwayBrowser/#/R-HSA-9612996 NTRK1,2 in ADCYAP1(2-742):ADCYAP1R1:NTRK1,2 autophosphorylates IEA Homo sapiens 30616 R-HSA-9613023 https://reactome.org/PathwayBrowser/#/R-HSA-9613023 NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates IEA Homo sapiens 30616 R-HSA-9613494 https://reactome.org/PathwayBrowser/#/R-HSA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition TAS Homo sapiens 30616 R-HSA-9613530 https://reactome.org/PathwayBrowser/#/R-HSA-9613530 PRKAA2 phosphorylates PLINs IEA Homo sapiens 30616 R-HSA-9615042 https://reactome.org/PathwayBrowser/#/R-HSA-9615042 Viral 2',5'-PDE cleaves 2'-5' oligoadenylates TAS Homo sapiens 30616 R-HSA-9617583 https://reactome.org/PathwayBrowser/#/R-HSA-9617583 CaMKII autophosphorylates IEA Homo sapiens 30616 R-HSA-9617596 https://reactome.org/PathwayBrowser/#/R-HSA-9617596 BAG6:GET4:UBL4A binds mislocalized membrane protein:SGTA and ASNA1:ATP IEA Homo sapiens 30616 R-HSA-9618750 https://reactome.org/PathwayBrowser/#/R-HSA-9618750 CaMKII phosphorylates AMPA receptor IEA Homo sapiens 30616 R-HSA-9619125 https://reactome.org/PathwayBrowser/#/R-HSA-9619125 CaMKK phosphorylates CAMK4 IEA Homo sapiens 30616 R-HSA-9619355 https://reactome.org/PathwayBrowser/#/R-HSA-9619355 CaMKK autophosphorylates in the cytosol TAS Homo sapiens 30616 R-HSA-9619367 https://reactome.org/PathwayBrowser/#/R-HSA-9619367 CaMKKs phosphorylate CAMK1 IEA Homo sapiens 30616 R-HSA-9619478 https://reactome.org/PathwayBrowser/#/R-HSA-9619478 CAMKK2 phosphorylates AMPK IEA Homo sapiens 30616 R-HSA-9619515 https://reactome.org/PathwayBrowser/#/R-HSA-9619515 AMPK phosphorylates MAPT IEA Homo sapiens 30616 R-HSA-9619783 https://reactome.org/PathwayBrowser/#/R-HSA-9619783 CAMK1 phosphorylates ARHGEF7-1 IEA Homo sapiens 30616 R-HSA-9619843 https://reactome.org/PathwayBrowser/#/R-HSA-9619843 ERKs phosphorylate RSKs IEA Homo sapiens 30616 R-HSA-9620004 https://reactome.org/PathwayBrowser/#/R-HSA-9620004 RSKs autophosphorylate IEA Homo sapiens 30616 R-HSA-9624014 https://reactome.org/PathwayBrowser/#/R-HSA-9624014 SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 TAS Homo sapiens 30616 R-HSA-9624526 https://reactome.org/PathwayBrowser/#/R-HSA-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR TAS Homo sapiens 30616 R-HSA-9624800 https://reactome.org/PathwayBrowser/#/R-HSA-9624800 CDK1 phosphorylates LBR TAS Homo sapiens 30616 R-HSA-9625487 https://reactome.org/PathwayBrowser/#/R-HSA-9625487 PTK2 autophosphorylates downstream of EGFR TAS Homo sapiens 30616 R-HSA-9626817 https://reactome.org/PathwayBrowser/#/R-HSA-9626817 PKC phosphorylates NCF1 TAS Homo sapiens 30616 R-HSA-9626832 https://reactome.org/PathwayBrowser/#/R-HSA-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 TAS Homo sapiens 30616 R-HSA-9626880 https://reactome.org/PathwayBrowser/#/R-HSA-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 TAS Homo sapiens 30616 R-HSA-9627056 https://reactome.org/PathwayBrowser/#/R-HSA-9627056 Procaspase 9 forms dimer TAS Homo sapiens 30616 R-HSA-9627089 https://reactome.org/PathwayBrowser/#/R-HSA-9627089 CASP9 is phosphorylated at T412 TAS Homo sapiens 30616 R-HSA-9632858 https://reactome.org/PathwayBrowser/#/R-HSA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation TAS Homo sapiens 30616 R-HSA-9632868 https://reactome.org/PathwayBrowser/#/R-HSA-9632868 CDKN1B is phosphorylated in response to estrogen TAS Homo sapiens 30616 R-HSA-9633008 https://reactome.org/PathwayBrowser/#/R-HSA-9633008 p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1 IEA Homo sapiens 30616 R-HSA-9633742 https://reactome.org/PathwayBrowser/#/R-HSA-9633742 EIF2AK4 (GCN2) dimer autophosphorylates IEA Homo sapiens 30616 R-HSA-9634390 https://reactome.org/PathwayBrowser/#/R-HSA-9634390 ERBB2 homodimer phosphorylates SHC1 TAS Homo sapiens 30616 R-HSA-9634702 https://reactome.org/PathwayBrowser/#/R-HSA-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 TAS Homo sapiens 30616 R-HSA-9645137 https://reactome.org/PathwayBrowser/#/R-HSA-9645137 Activator phosphorylates STAT5 IEA Homo sapiens 30616 R-HSA-9645442 https://reactome.org/PathwayBrowser/#/R-HSA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex TAS Homo sapiens 30616 R-HSA-9645535 https://reactome.org/PathwayBrowser/#/R-HSA-9645535 ALPK1 phosphorylates TIFA TAS Homo sapiens 30616 R-HSA-9648089 https://reactome.org/PathwayBrowser/#/R-HSA-9648089 NEK6 and NEK7 phosphorylate EML4 TAS Homo sapiens 30616 R-HSA-9648883 https://reactome.org/PathwayBrowser/#/R-HSA-9648883 p-T-EIF2AK1:ferriheme dimer autophosphorylates IEA Homo sapiens 30616 R-HSA-9648888 https://reactome.org/PathwayBrowser/#/R-HSA-9648888 p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) IEA Homo sapiens 30616 R-HSA-964958 https://reactome.org/PathwayBrowser/#/R-HSA-964958 2xPDXK:2xZn2+ phosphorylates PXA TAS Homo sapiens 30616 R-HSA-964962 https://reactome.org/PathwayBrowser/#/R-HSA-964962 2xPDKX:2xZn2+ phosphorylates PDX TAS Homo sapiens 30616 R-HSA-964970 https://reactome.org/PathwayBrowser/#/R-HSA-964970 2xPDXK:2xZn2+ phosphorylates PXL TAS Homo sapiens 30616 R-HSA-9652165 https://reactome.org/PathwayBrowser/#/R-HSA-9652165 MAP2K mutants constitutively phosphorylate MAPKs TAS Homo sapiens 30616 R-HSA-9653503 https://reactome.org/PathwayBrowser/#/R-HSA-9653503 KRAS4B is phosphorylated on serine 181 TAS Homo sapiens 30616 R-HSA-9656212 https://reactome.org/PathwayBrowser/#/R-HSA-9656212 Phosphorylation of RAF1 mutants TAS Homo sapiens 30616 R-HSA-9656214 https://reactome.org/PathwayBrowser/#/R-HSA-9656214 MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants TAS Homo sapiens 30616 R-HSA-9656215 https://reactome.org/PathwayBrowser/#/R-HSA-9656215 RAF1 mutant complexes phosphorylate MAP2K dimer TAS Homo sapiens 30616 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 30616 R-HSA-9660822 https://reactome.org/PathwayBrowser/#/R-HSA-9660822 ATP binds P2RX4,7 TAS Homo sapiens 30616 R-HSA-9661417 https://reactome.org/PathwayBrowser/#/R-HSA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-9662114 https://reactome.org/PathwayBrowser/#/R-HSA-9662114 ATP2B2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region IEA Homo sapiens 30616 R-HSA-9662823 https://reactome.org/PathwayBrowser/#/R-HSA-9662823 PLK2, MAPK14 phosphorylate ADAM17 TAS Homo sapiens 30616 R-HSA-9664214 https://reactome.org/PathwayBrowser/#/R-HSA-9664214 ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region IEA Homo sapiens 30616 R-HSA-9664261 https://reactome.org/PathwayBrowser/#/R-HSA-9664261 Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK TAS Homo sapiens 30616 R-HSA-9664275 https://reactome.org/PathwayBrowser/#/R-HSA-9664275 Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers TAS Homo sapiens 30616 R-HSA-9664278 https://reactome.org/PathwayBrowser/#/R-HSA-9664278 Phosphorylation and activation of PLCG due to FCGR3A effect TAS Homo sapiens 30616 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 30616 R-HSA-9664664 https://reactome.org/PathwayBrowser/#/R-HSA-9664664 PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 converts PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-9664940 https://reactome.org/PathwayBrowser/#/R-HSA-9664940 PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR converts PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-9664976 https://reactome.org/PathwayBrowser/#/R-HSA-9664976 Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1 TAS Homo sapiens 30616 R-HSA-9665032 https://reactome.org/PathwayBrowser/#/R-HSA-9665032 Phosphorylated heterodimers of ERBB2 KD mutants and EGFR phosphorylate PLCG1 TAS Homo sapiens 30616 R-HSA-9665389 https://reactome.org/PathwayBrowser/#/R-HSA-9665389 Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate TAS Homo sapiens 30616 R-HSA-9665406 https://reactome.org/PathwayBrowser/#/R-HSA-9665406 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate SHC1 TAS Homo sapiens 30616 R-HSA-9665407 https://reactome.org/PathwayBrowser/#/R-HSA-9665407 PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3 TAS Homo sapiens 30616 R-HSA-9665411 https://reactome.org/PathwayBrowser/#/R-HSA-9665411 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate PLCG1 TAS Homo sapiens 30616 R-HSA-9665515 https://reactome.org/PathwayBrowser/#/R-HSA-9665515 P2RX4,7 binds itself to form trimeric non-selective cation channels TAS Homo sapiens 30616 R-HSA-9665524 https://reactome.org/PathwayBrowser/#/R-HSA-9665524 ATP translocates from cytosol to extracellular space (stimuated by C3AR1:C3a) TAS Homo sapiens 30616 R-HSA-9665704 https://reactome.org/PathwayBrowser/#/R-HSA-9665704 Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1 TAS Homo sapiens 30616 R-HSA-9665705 https://reactome.org/PathwayBrowser/#/R-HSA-9665705 Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1 TAS Homo sapiens 30616 R-HSA-9665709 https://reactome.org/PathwayBrowser/#/R-HSA-9665709 ERBB2 TMD/JMD heterodimers trans-autophosphorylate TAS Homo sapiens 30616 R-HSA-9666425 https://reactome.org/PathwayBrowser/#/R-HSA-9666425 p-6Y-SYK phosphorylates VAV1,2,3 TAS Homo sapiens 30616 R-HSA-9666458 https://reactome.org/PathwayBrowser/#/R-HSA-9666458 IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole TAS Homo sapiens 30616 R-HSA-9668415 https://reactome.org/PathwayBrowser/#/R-HSA-9668415 VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope TAS Homo sapiens 30616 R-HSA-9668419 https://reactome.org/PathwayBrowser/#/R-HSA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites TAS Homo sapiens 30616 R-HSA-9669890 https://reactome.org/PathwayBrowser/#/R-HSA-9669890 Constitutive phosphorylation of kinase domain KIT mutants TAS Homo sapiens 30616 R-HSA-9669911 https://reactome.org/PathwayBrowser/#/R-HSA-9669911 Phosphorylation of juxtamembrane domain KIT mutants TAS Homo sapiens 30616 R-HSA-9670412 https://reactome.org/PathwayBrowser/#/R-HSA-9670412 Phosphorylation of STATs downstream of KIT mutants TAS Homo sapiens 30616 R-HSA-9670418 https://reactome.org/PathwayBrowser/#/R-HSA-9670418 Phosphorylation of JAK2 downstream of KIT mutants TAS Homo sapiens 30616 R-HSA-9670433 https://reactome.org/PathwayBrowser/#/R-HSA-9670433 KIT mutants:PI3K catalyze synthesis of PIP3 TAS Homo sapiens 30616 R-HSA-9672162 https://reactome.org/PathwayBrowser/#/R-HSA-9672162 PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of PDGFRA extracellular domain dimers TAS Homo sapiens 30616 R-HSA-9672173 https://reactome.org/PathwayBrowser/#/R-HSA-9672173 Autophosphorylation of PDGFRA extracellular domain dimers TAS Homo sapiens 30616 R-HSA-9672175 https://reactome.org/PathwayBrowser/#/R-HSA-9672175 Autophosphorylation of PDGFR mutant dimers TAS Homo sapiens 30616 R-HSA-9672177 https://reactome.org/PathwayBrowser/#/R-HSA-9672177 PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of mutant PDGFR TAS Homo sapiens 30616 R-HSA-9673284 https://reactome.org/PathwayBrowser/#/R-HSA-9673284 GTP-bound RAC1 contributes to MAPK8 activation TAS Homo sapiens 30616 R-HSA-9673346 https://reactome.org/PathwayBrowser/#/R-HSA-9673346 Unknown kinase phosphorylates p-DVL IEA Homo sapiens 30616 R-HSA-9673756 https://reactome.org/PathwayBrowser/#/R-HSA-9673756 Autophosphorylation of cytosolic PDGFRA and PDGFRB fusion proteins TAS Homo sapiens 30616 R-HSA-9673761 https://reactome.org/PathwayBrowser/#/R-HSA-9673761 Autophosphorylation of membrane-tethered fusions of PDGFRA or PDGFRB TAS Homo sapiens 30616 R-HSA-9673789 https://reactome.org/PathwayBrowser/#/R-HSA-9673789 Activated JNK phosphorylates c-JUN TAS Homo sapiens 30616 R-HSA-9674546 https://reactome.org/PathwayBrowser/#/R-HSA-9674546 CSF3 dimer:2xCSF3R:LYN:JAK1 induces phosphorylation of JAK1 IEA Homo sapiens 30616 R-HSA-9674558 https://reactome.org/PathwayBrowser/#/R-HSA-9674558 p-Y-JAK1 phosphorylates CSF3R in CSF3 dimer:2xCSF3R:LYN:p-Y-JAK1 IEA Homo sapiens 30616 R-HSA-9674567 https://reactome.org/PathwayBrowser/#/R-HSA-9674567 p-Y-JAK1,2 phosphorylates STAT1,3,5 in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-Y-JAK2:p-TYK2 IEA Homo sapiens 30616 R-HSA-9674808 https://reactome.org/PathwayBrowser/#/R-HSA-9674808 CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 binds and phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2) IEA Homo sapiens 30616 R-HSA-9676071 https://reactome.org/PathwayBrowser/#/R-HSA-9676071 CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK IEA Homo sapiens 30616 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 30616 R-HSA-9680248 https://reactome.org/PathwayBrowser/#/R-HSA-9680248 Phosphorylation of extracellular domain KIT mutants TAS Homo sapiens 30616 R-HSA-9680348 https://reactome.org/PathwayBrowser/#/R-HSA-9680348 PIK3R1:PIK3CA,B,D (PI3K), PLCG2 (PLCgamma2), SHC1 (SHC), PTPN11 (SHP2), GRB2:GAB2, GRB2:GAB3, GRAP2 (MONA), CBL:GRB2, INPP5D (SHIP1), INPPL1 (SHIP2) bind PolyUb,p-8Y-CSF1R and are activated IEA Homo sapiens 30616 R-HSA-9680389 https://reactome.org/PathwayBrowser/#/R-HSA-9680389 CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2 IEA Homo sapiens 30616 R-HSA-9682695 https://reactome.org/PathwayBrowser/#/R-HSA-9682695 nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template TAS Homo sapiens 30616 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 30616 R-HSA-9684118 https://reactome.org/PathwayBrowser/#/R-HSA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER TAS Homo sapiens 30616 R-HSA-9685519 https://reactome.org/PathwayBrowser/#/R-HSA-9685519 Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) TAS Homo sapiens 30616 R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 30616 R-HSA-9686521 https://reactome.org/PathwayBrowser/#/R-HSA-9686521 CDK2:CCNA phosphorylates TERF2 TAS Homo sapiens 30616 R-HSA-9687625 https://reactome.org/PathwayBrowser/#/R-HSA-9687625 ATP binds MLKL TAS Homo sapiens 30616 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 30616 R-HSA-9693589 https://reactome.org/PathwayBrowser/#/R-HSA-9693589 SARS-CoV-1 dsRNA intermediates bind DDX58 TAS Homo sapiens 30616 R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 30616 R-HSA-9694471 https://reactome.org/PathwayBrowser/#/R-HSA-9694471 Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) TAS Homo sapiens 30616 R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 30616 R-HSA-9695834 https://reactome.org/PathwayBrowser/#/R-HSA-9695834 Constitutive phosphorylation of FLT3 mutants TAS Homo sapiens 30616 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 30616 R-HSA-9698003 https://reactome.org/PathwayBrowser/#/R-HSA-9698003 FLT3 mutants phosphorylate GAB2 TAS Homo sapiens 30616 R-HSA-9698005 https://reactome.org/PathwayBrowser/#/R-HSA-9698005 FLT3 ITD mutants phosphorylate STAT5 TAS Homo sapiens 30616 R-HSA-9699578 https://reactome.org/PathwayBrowser/#/R-HSA-9699578 Active FLT3 phosphorylates CDKN1B TAS Homo sapiens 30616 R-HSA-9699579 https://reactome.org/PathwayBrowser/#/R-HSA-9699579 AKT phosphorylates FOXO3 downstream of FLT3 TAS Homo sapiens 30616 R-HSA-9700164 https://reactome.org/PathwayBrowser/#/R-HSA-9700164 Active ALK phosphorylates FRS2 IEA Homo sapiens 30616 R-HSA-9700168 https://reactome.org/PathwayBrowser/#/R-HSA-9700168 Active ALK phosphorylates IRS1 TAS Homo sapiens 30616 R-HSA-9700171 https://reactome.org/PathwayBrowser/#/R-HSA-9700171 Active ALK phosphorylates PLCG1 TAS Homo sapiens 30616 R-HSA-9700175 https://reactome.org/PathwayBrowser/#/R-HSA-9700175 Active ALK phosphorylates SHC1 TAS Homo sapiens 30616 R-HSA-9700181 https://reactome.org/PathwayBrowser/#/R-HSA-9700181 Autophosphorylation of ALK fusions TAS Homo sapiens 30616 R-HSA-9700186 https://reactome.org/PathwayBrowser/#/R-HSA-9700186 Autophosphorylation of point mutants of ALK TAS Homo sapiens 30616 R-HSA-9700193 https://reactome.org/PathwayBrowser/#/R-HSA-9700193 ALK mutants phosphorylate SHC1 TAS Homo sapiens 30616 R-HSA-9700647 https://reactome.org/PathwayBrowser/#/R-HSA-9700647 Active ALK phosphorylates SRC IEA Homo sapiens 30616 R-HSA-9701488 https://reactome.org/PathwayBrowser/#/R-HSA-9701488 Active ALK phosphorylates JAK3 TAS Homo sapiens 30616 R-HSA-9703437 https://reactome.org/PathwayBrowser/#/R-HSA-9703437 FLT3 fusion dimers autophosphorylate TAS Homo sapiens 30616 R-HSA-9703438 https://reactome.org/PathwayBrowser/#/R-HSA-9703438 FLT3 fusions phosphorylate GAB2 TAS Homo sapiens 30616 R-HSA-9705137 https://reactome.org/PathwayBrowser/#/R-HSA-9705137 TBK1 or IKBKE forms homodimers TAS Homo sapiens 30616 R-HSA-9705145 https://reactome.org/PathwayBrowser/#/R-HSA-9705145 TBK1, IKBKE form homodimers TAS Homo sapiens 30616 R-HSA-9705320 https://reactome.org/PathwayBrowser/#/R-HSA-9705320 TBK1, IKBKE are autophosphorylated at Ser172 TAS Homo sapiens 30616 R-HSA-9705323 https://reactome.org/PathwayBrowser/#/R-HSA-9705323 Phosphorylation of TBK1/IKBKE TAS Homo sapiens 30616 R-HSA-9705925 https://reactome.org/PathwayBrowser/#/R-HSA-9705925 Androgens binds AR (in the HSP90 chaperone complex) TAS Homo sapiens 30616 R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 30616 R-HSA-9706344 https://reactome.org/PathwayBrowser/#/R-HSA-9706344 FLT3 phosphorylates GRB10 TAS Homo sapiens 30616 R-HSA-9706350 https://reactome.org/PathwayBrowser/#/R-HSA-9706350 FLT3 phosphorylates CBL TAS Homo sapiens 30616 R-HSA-9706390 https://reactome.org/PathwayBrowser/#/R-HSA-9706390 RHOBTB3 binds interacting proteins at trans-Golgi network TAS Homo sapiens 30616 R-HSA-9706393 https://reactome.org/PathwayBrowser/#/R-HSA-9706393 RHOBTB3 binds ATP TAS Homo sapiens 30616 R-HSA-9706399 https://reactome.org/PathwayBrowser/#/R-HSA-9706399 RHOBTB3 hydrolyzes ATP TAS Homo sapiens 30616 R-HSA-9706837 https://reactome.org/PathwayBrowser/#/R-HSA-9706837 AR binds AR antagonists TAS Homo sapiens 30616 R-HSA-9709547 https://reactome.org/PathwayBrowser/#/R-HSA-9709547 ESTG binds ESR2:chaperone complex TAS Homo sapiens 30616 R-HSA-9709918 https://reactome.org/PathwayBrowser/#/R-HSA-9709918 PTK6 phosphorylates STAT3 IEA Homo sapiens 30616 R-HSA-9712082 https://reactome.org/PathwayBrowser/#/R-HSA-9712082 ALK fusions phosphorylate IRS1 TAS Homo sapiens 30616 R-HSA-9712084 https://reactome.org/PathwayBrowser/#/R-HSA-9712084 PI3K synthesizes PIP3 downstream of ALK mutants TAS Homo sapiens 30616 R-HSA-9712085 https://reactome.org/PathwayBrowser/#/R-HSA-9712085 ALK mutants phosphorylate STAT3 TAS Homo sapiens 30616 R-HSA-9712086 https://reactome.org/PathwayBrowser/#/R-HSA-9712086 ALK fusions phosphorylate PLCG1 TAS Homo sapiens 30616 R-HSA-9712087 https://reactome.org/PathwayBrowser/#/R-HSA-9712087 ALK fusions phosphorylate FRS TAS Homo sapiens 30616 R-HSA-9712183 https://reactome.org/PathwayBrowser/#/R-HSA-9712183 ADCY3:GNAL:GTP converts ATP to cAMP IEA Homo sapiens 30616 R-HSA-9716913 https://reactome.org/PathwayBrowser/#/R-HSA-9716913 ESR1 binds ESR1 antagonists TAS Homo sapiens 30616 R-HSA-9716947 https://reactome.org/PathwayBrowser/#/R-HSA-9716947 ESR1 binds ESR1 agonists TAS Homo sapiens 30616 R-HSA-9717392 https://reactome.org/PathwayBrowser/#/R-HSA-9717392 CALHM1:CALHM3 transports ATP from the cytosol to the extracellular region IEA Homo sapiens 30616 R-HSA-9725030 https://reactome.org/PathwayBrowser/#/R-HSA-9725030 MAPK1 phsophorylates ZC3HCF1 in a NPM-ALK-dependent manner TAS Homo sapiens 30616 R-HSA-9725855 https://reactome.org/PathwayBrowser/#/R-HSA-9725855 NR3C2 binds NR3C2 antagonists TAS Homo sapiens 30616 R-HSA-9725885 https://reactome.org/PathwayBrowser/#/R-HSA-9725885 P4 bind PGR (in the HSP90 chaperone complex) TAS Homo sapiens 30616 R-HSA-9726509 https://reactome.org/PathwayBrowser/#/R-HSA-9726509 NR3C2 binds fludrocortisone TAS Homo sapiens 30616 R-HSA-9726580 https://reactome.org/PathwayBrowser/#/R-HSA-9726580 PGR binds PGR agonists TAS Homo sapiens 30616 R-HSA-9726621 https://reactome.org/PathwayBrowser/#/R-HSA-9726621 PGR binds PGR antagonists TAS Homo sapiens 30616 R-HSA-9726848 https://reactome.org/PathwayBrowser/#/R-HSA-9726848 SRC phosphorylates RHOU IEA Homo sapiens 30616 R-HSA-9727198 https://reactome.org/PathwayBrowser/#/R-HSA-9727198 ATP4A:ATP4B exchanges K+ for H+ TAS Homo sapiens 30616 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 30616 R-HSA-9729300 https://reactome.org/PathwayBrowser/#/R-HSA-9729300 Unknown kinase phosphorylates nucleoprotein TAS Homo sapiens 30616 R-HSA-9729318 https://reactome.org/PathwayBrowser/#/R-HSA-9729318 CSNK1A1 phosphorylates nucleoprotein TAS Homo sapiens 30616 R-HSA-9729330 https://reactome.org/PathwayBrowser/#/R-HSA-9729330 SRPK1/2 phosphorylates nucleoprotein TAS Homo sapiens 30616 R-HSA-9731111 https://reactome.org/PathwayBrowser/#/R-HSA-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 TAS Homo sapiens 30616 R-HSA-9732738 https://reactome.org/PathwayBrowser/#/R-HSA-9732738 JAK1-mediated phosphorylation of RAF1 TAS Homo sapiens 30616 R-HSA-9732753 https://reactome.org/PathwayBrowser/#/R-HSA-9732753 JAK1-activated RAF1 phosphorylates MAPKs TAS Homo sapiens 30616 R-HSA-9733314 https://reactome.org/PathwayBrowser/#/R-HSA-9733314 CSF1R trans-autophosphorylates on tyrosine-561 IEA Homo sapiens 30616 R-HSA-9733323 https://reactome.org/PathwayBrowser/#/R-HSA-9733323 Src family kinases phosphorylate CBL in CSF1 dimer:p-Y561-CSF1R dimer:CBL IEA Homo sapiens 30616 R-HSA-9734535 https://reactome.org/PathwayBrowser/#/R-HSA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA TAS Homo sapiens 30616 R-HSA-9734547 https://reactome.org/PathwayBrowser/#/R-HSA-9734547 JAK2-activated MAPKs phosphorylate YBX1 TAS Homo sapiens 30616 R-HSA-9734687 https://reactome.org/PathwayBrowser/#/R-HSA-9734687 ORC6 is phosphorylated on T195 TAS Homo sapiens 30616 R-HSA-9748949 https://reactome.org/PathwayBrowser/#/R-HSA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP TAS Homo sapiens 30616 R-HSA-9748957 https://reactome.org/PathwayBrowser/#/R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP TAS Homo sapiens 30616 R-HSA-9748963 https://reactome.org/PathwayBrowser/#/R-HSA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP TAS Homo sapiens 30616 R-HSA-9748969 https://reactome.org/PathwayBrowser/#/R-HSA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP TAS Homo sapiens 30616 R-HSA-9748999 https://reactome.org/PathwayBrowser/#/R-HSA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP TAS Homo sapiens 30616 R-HSA-9749350 https://reactome.org/PathwayBrowser/#/R-HSA-9749350 ATP-dependent release of CDT1 from the OCCM complex IEA Homo sapiens 30616 R-HSA-9749971 https://reactome.org/PathwayBrowser/#/R-HSA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA TAS Homo sapiens 30616 R-HSA-9750546 https://reactome.org/PathwayBrowser/#/R-HSA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-9750617 https://reactome.org/PathwayBrowser/#/R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-9750656 https://reactome.org/PathwayBrowser/#/R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells TAS Homo sapiens 30616 R-HSA-975103 https://reactome.org/PathwayBrowser/#/R-HSA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation TAS Homo sapiens 30616 R-HSA-975106 https://reactome.org/PathwayBrowser/#/R-HSA-975106 Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 30616 R-HSA-975125 https://reactome.org/PathwayBrowser/#/R-HSA-975125 Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 30616 R-HSA-975134 https://reactome.org/PathwayBrowser/#/R-HSA-975134 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 TAS Homo sapiens 30616 R-HSA-975139 https://reactome.org/PathwayBrowser/#/R-HSA-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation TAS Homo sapiens 30616 R-HSA-975160 https://reactome.org/PathwayBrowser/#/R-HSA-975160 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 TAS Homo sapiens 30616 R-HSA-975170 https://reactome.org/PathwayBrowser/#/R-HSA-975170 IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 30616 R-HSA-975180 https://reactome.org/PathwayBrowser/#/R-HSA-975180 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 30616 R-HSA-9753278 https://reactome.org/PathwayBrowser/#/R-HSA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 30616 R-HSA-9753283 https://reactome.org/PathwayBrowser/#/R-HSA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 30616 R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 30616 R-HSA-9754974 https://reactome.org/PathwayBrowser/#/R-HSA-9754974 ADK phosphorylates RBV TAS Homo sapiens 30616 R-HSA-9754978 https://reactome.org/PathwayBrowser/#/R-HSA-9754978 Unknown kinase phosphorylates RBV-MP TAS Homo sapiens 30616 R-HSA-9755013 https://reactome.org/PathwayBrowser/#/R-HSA-9755013 NME1,2 hexamers phosphorylate RBV-DP TAS Homo sapiens 30616 R-HSA-9755258 https://reactome.org/PathwayBrowser/#/R-HSA-9755258 DDX58 binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 30616 R-HSA-9758486 https://reactome.org/PathwayBrowser/#/R-HSA-9758486 Unknown kinase phosphorylates 9b TAS Homo sapiens 30616 R-HSA-975853 https://reactome.org/PathwayBrowser/#/R-HSA-975853 Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR TAS Homo sapiens 30616 R-HSA-975861 https://reactome.org/PathwayBrowser/#/R-HSA-975861 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex TAS Homo sapiens 30616 R-HSA-975865 https://reactome.org/PathwayBrowser/#/R-HSA-975865 IRAK4 autophosphorylation within the complex activated TLR:MyD88 TAS Homo sapiens 30616 R-HSA-975874 https://reactome.org/PathwayBrowser/#/R-HSA-975874 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex TAS Homo sapiens 30616 R-HSA-975878 https://reactome.org/PathwayBrowser/#/R-HSA-975878 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR TAS Homo sapiens 30616 R-HSA-9759206 https://reactome.org/PathwayBrowser/#/R-HSA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol TAS Homo sapiens 30616 R-HSA-9759454 https://reactome.org/PathwayBrowser/#/R-HSA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells TAS Homo sapiens 30616 R-HSA-9759461 https://reactome.org/PathwayBrowser/#/R-HSA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells TAS Homo sapiens 30616 R-HSA-9760094 https://reactome.org/PathwayBrowser/#/R-HSA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer TAS Homo sapiens 30616 R-HSA-9762094 https://reactome.org/PathwayBrowser/#/R-HSA-9762094 GSK3B phosphorylates p-NFE2L2 TAS Homo sapiens 30616 R-HSA-9762209 https://reactome.org/PathwayBrowser/#/R-HSA-9762209 BACH1 is phosphorylated at tyrosine 483 TAS Homo sapiens 30616 R-HSA-9766532 https://reactome.org/PathwayBrowser/#/R-HSA-9766532 SQSTM1 oligomer is phosphorylated TAS Homo sapiens 30616 R-HSA-9769115 https://reactome.org/PathwayBrowser/#/R-HSA-9769115 MAPK1,(MAPK3) phosphorylates NPAS4 IEA Homo sapiens 30616 R-HSA-9770129 https://reactome.org/PathwayBrowser/#/R-HSA-9770129 Formation of the Spliceosomal A complex TAS Homo sapiens 30616 R-HSA-9770131 https://reactome.org/PathwayBrowser/#/R-HSA-9770131 Formation of the Spliceosomal B* complex TAS Homo sapiens 30616 R-HSA-9770141 https://reactome.org/PathwayBrowser/#/R-HSA-9770141 Formation of the Spliceosomal C* complex TAS Homo sapiens 30616 R-HSA-9770142 https://reactome.org/PathwayBrowser/#/R-HSA-9770142 Formation of the Spliceosomal B complex TAS Homo sapiens 30616 R-HSA-9770145 https://reactome.org/PathwayBrowser/#/R-HSA-9770145 Formation of the Spliceosomal Bact complex TAS Homo sapiens 30616 R-HSA-9770847 https://reactome.org/PathwayBrowser/#/R-HSA-9770847 Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) TAS Homo sapiens 30616 R-HSA-9772351 https://reactome.org/PathwayBrowser/#/R-HSA-9772351 Disassembly of the Intron Lariat Spliceosome (new) TAS Homo sapiens 30616 R-HSA-9773803 https://reactome.org/PathwayBrowser/#/R-HSA-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor TAS Homo sapiens 30616 R-HSA-9794120 https://reactome.org/PathwayBrowser/#/R-HSA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space TAS Homo sapiens 30616 R-HSA-9794572 https://reactome.org/PathwayBrowser/#/R-HSA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space TAS Homo sapiens 30616 R-HSA-9796053 https://reactome.org/PathwayBrowser/#/R-HSA-9796053 PRKCI phosphorylates NFE2L2 TAS Homo sapiens 30616 R-HSA-9796067 https://reactome.org/PathwayBrowser/#/R-HSA-9796067 PRKAA2 phosphorylates nuclear NFE2L2 TAS Homo sapiens 30616 R-HSA-9796081 https://reactome.org/PathwayBrowser/#/R-HSA-9796081 EIF2AK3 phosphorylates NFE2L2 IEA Homo sapiens 30616 R-HSA-9815501 https://reactome.org/PathwayBrowser/#/R-HSA-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 TAS Homo sapiens 30616 R-HSA-9817397 https://reactome.org/PathwayBrowser/#/R-HSA-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 TAS Homo sapiens 30616 R-HSA-9818789 https://reactome.org/PathwayBrowser/#/R-HSA-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 TAS Homo sapiens 30616 R-HSA-9819106 https://reactome.org/PathwayBrowser/#/R-HSA-9819106 ULK1 phosphorylates RIPK1 at S357 TAS Homo sapiens 30616 R-HSA-9821967 https://reactome.org/PathwayBrowser/#/R-HSA-9821967 SRPK1 phosphorylates PRM2 in PRM2:dsDNA IEA Homo sapiens 30616 R-HSA-9821982 https://reactome.org/PathwayBrowser/#/R-HSA-9821982 SRPK1 phosphorylates PRM1 in PRM1:dsDNA IEA Homo sapiens 30616 R-HSA-9823906 https://reactome.org/PathwayBrowser/#/R-HSA-9823906 TBK1 is phosphorylated within the activated TLR4 complex TAS Homo sapiens 30616 R-HSA-9824882 https://reactome.org/PathwayBrowser/#/R-HSA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex TAS Homo sapiens 30616 R-HSA-9824977 https://reactome.org/PathwayBrowser/#/R-HSA-9824977 MAPK1-dependent phosphorylation of MITF-M TAS Homo sapiens 30616 R-HSA-9824994 https://reactome.org/PathwayBrowser/#/R-HSA-9824994 RPS6KA1-dependent phosphorylation of MITF-M TAS Homo sapiens 30616 R-HSA-9824995 https://reactome.org/PathwayBrowser/#/R-HSA-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 TAS Homo sapiens 30616 R-HSA-9824999 https://reactome.org/PathwayBrowser/#/R-HSA-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 TAS Homo sapiens 30616 R-HSA-9825759 https://reactome.org/PathwayBrowser/#/R-HSA-9825759 MAPK-dependent phosphorylation of KARS TAS Homo sapiens 30616 R-HSA-982807 https://reactome.org/PathwayBrowser/#/R-HSA-982807 JAK2 phosphorylation of GHR TAS Homo sapiens 30616 R-HSA-982810 https://reactome.org/PathwayBrowser/#/R-HSA-982810 JAK2 phosphorylation TAS Homo sapiens 30616 R-HSA-9828205 https://reactome.org/PathwayBrowser/#/R-HSA-9828205 TBK1 is phosphorylated within the activated TLR3 complex TAS Homo sapiens 30616 R-HSA-9830706 https://reactome.org/PathwayBrowser/#/R-HSA-9830706 IKKε (IKBKE) is phosphorylated within the activated TLR3 complex TAS Homo sapiens 30616 R-HSA-983140 https://reactome.org/PathwayBrowser/#/R-HSA-983140 Transfer of Ub from E2 to substrate and release of E2 TAS Homo sapiens 30616 R-HSA-983144 https://reactome.org/PathwayBrowser/#/R-HSA-983144 Transport of Antigen peptide in to ER TAS Homo sapiens 30616 R-HSA-9831514 https://reactome.org/PathwayBrowser/#/R-HSA-9831514 CK2 phosphorylates nascent P TAS Homo sapiens 30616 R-HSA-983153 https://reactome.org/PathwayBrowser/#/R-HSA-983153 E1 mediated ubiquitin activation TAS Homo sapiens 30616 R-HSA-983156 https://reactome.org/PathwayBrowser/#/R-HSA-983156 Polyubiquitination of substrate TAS Homo sapiens 30616 R-HSA-9831712 https://reactome.org/PathwayBrowser/#/R-HSA-9831712 M dimer is phosphorylated TAS Homo sapiens 30616 R-HSA-983259 https://reactome.org/PathwayBrowser/#/R-HSA-983259 Kinesins move along microtubules consuming ATP TAS Homo sapiens 30616 R-HSA-9833031 https://reactome.org/PathwayBrowser/#/R-HSA-9833031 Polyadenylation of respiratory syncytial virus subgenomic positive-sense mRNAs TAS Homo sapiens 30616 R-HSA-9833820 https://reactome.org/PathwayBrowser/#/R-HSA-9833820 PKR dimer autophosphorylates TAS Homo sapiens 30616 R-HSA-9833973 https://reactome.org/PathwayBrowser/#/R-HSA-9833973 ISGylation of PKR TAS Homo sapiens 30616 R-HSA-9835885 https://reactome.org/PathwayBrowser/#/R-HSA-9835885 p-PKR dimer phosphorylates eIF2-alpha TAS Homo sapiens 30616 R-HSA-9836159 https://reactome.org/PathwayBrowser/#/R-HSA-9836159 p-PKR dimer phosphorylates DHX9 TAS Homo sapiens 30616 R-HSA-9836184 https://reactome.org/PathwayBrowser/#/R-HSA-9836184 p-PKR dimer phosphorylates CDK1 TAS Homo sapiens 30616 R-HSA-9836322 https://reactome.org/PathwayBrowser/#/R-HSA-9836322 p-PKR dimer phosphorylates MKK6 TAS Homo sapiens 30616 R-HSA-9836362 https://reactome.org/PathwayBrowser/#/R-HSA-9836362 p-PKR dimer phosphorylates TP53 tetramer TAS Homo sapiens 30616 R-HSA-9836383 https://reactome.org/PathwayBrowser/#/R-HSA-9836383 p-PKR dimer phosphorylates ILF3:ILF2 TAS Homo sapiens 30616 R-HSA-9836404 https://reactome.org/PathwayBrowser/#/R-HSA-9836404 p-PKR dimer phosphorylates MAPT TAS Homo sapiens 30616 R-HSA-9836435 https://reactome.org/PathwayBrowser/#/R-HSA-9836435 p-PKR dimer phosphorylates SNCA TAS Homo sapiens 30616 R-HSA-9836449 https://reactome.org/PathwayBrowser/#/R-HSA-9836449 p-PKR dimer phosphorylates HIV tat TAS Homo sapiens 30616 R-HSA-9836515 https://reactome.org/PathwayBrowser/#/R-HSA-9836515 p-PKR dimer phosphorylates PTPN2 TAS Homo sapiens 30616 R-HSA-9836617 https://reactome.org/PathwayBrowser/#/R-HSA-9836617 p-PKR dimer phosphorylates SPHK1 TAS Homo sapiens 30616 R-HSA-9836664 https://reactome.org/PathwayBrowser/#/R-HSA-9836664 p-PKR dimer phosphorylates PPP2R5A TAS Homo sapiens 30616 R-HSA-9836769 https://reactome.org/PathwayBrowser/#/R-HSA-9836769 RSV dsRNA binds DDX58 TAS Homo sapiens 30616 R-HSA-9836927 https://reactome.org/PathwayBrowser/#/R-HSA-9836927 SUPV3L1 unwinds double-stranded mitochondiral RNA TAS Homo sapiens 30616 R-HSA-983703 https://reactome.org/PathwayBrowser/#/R-HSA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) TAS Homo sapiens 30616 R-HSA-983707 https://reactome.org/PathwayBrowser/#/R-HSA-983707 SYK autophosphorylates at the activated BCR TAS Homo sapiens 30616 R-HSA-983709 https://reactome.org/PathwayBrowser/#/R-HSA-983709 LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) IEA Homo sapiens 30616 R-HSA-9837231 https://reactome.org/PathwayBrowser/#/R-HSA-9837231 ISGylation of BECN1 TAS Homo sapiens 30616 R-HSA-9837337 https://reactome.org/PathwayBrowser/#/R-HSA-9837337 DCAKD phosphorylates DP-CoA TAS Homo sapiens 30616 R-HSA-9838004 https://reactome.org/PathwayBrowser/#/R-HSA-9838004 LONP1 degrades mitochondrial inner membrane proteins TAS Homo sapiens 30616 R-HSA-9838081 https://reactome.org/PathwayBrowser/#/R-HSA-9838081 LONP1 degrades mitochondrial matrix proteins TAS Homo sapiens 30616 R-HSA-9838289 https://reactome.org/PathwayBrowser/#/R-HSA-9838289 CLPXP degrades mitochondrial matrix proteins TAS Homo sapiens 30616 R-HSA-9838321 https://reactome.org/PathwayBrowser/#/R-HSA-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix TAS Homo sapiens 30616 R-HSA-9839059 https://reactome.org/PathwayBrowser/#/R-HSA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) TAS Homo sapiens 30616 R-HSA-9839105 https://reactome.org/PathwayBrowser/#/R-HSA-9839105 AFG3L2 degrades mitochondrial matrix proteins TAS Homo sapiens 30616 R-HSA-9839113 https://reactome.org/PathwayBrowser/#/R-HSA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins TAS Homo sapiens 30616 R-HSA-9839146 https://reactome.org/PathwayBrowser/#/R-HSA-9839146 YME1L1 degrades mitochondrial inner membrane proteins IEA Homo sapiens 30616 R-HSA-9839751 https://reactome.org/PathwayBrowser/#/R-HSA-9839751 YME1L1 degrades mitochondrial intermembrane space proteins IEA Homo sapiens 30616 R-HSA-9840564 https://reactome.org/PathwayBrowser/#/R-HSA-9840564 OMA1 hydrolyzes YME1L1 TAS Homo sapiens 30616 R-HSA-9842648 https://reactome.org/PathwayBrowser/#/R-HSA-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 TAS Homo sapiens 30616 R-HSA-9842651 https://reactome.org/PathwayBrowser/#/R-HSA-9842651 Active LTK receptor phosphorylates SHC1 TAS Homo sapiens 30616 R-HSA-9842666 https://reactome.org/PathwayBrowser/#/R-HSA-9842666 Active LTK phosphorylates IRS1 TAS Homo sapiens 30616 R-HSA-9842667 https://reactome.org/PathwayBrowser/#/R-HSA-9842667 CLIP1-LTK fusion autophosphorylates TAS Homo sapiens 30616 R-HSA-9843721 https://reactome.org/PathwayBrowser/#/R-HSA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region TAS Homo sapiens 30616 R-HSA-9845033 https://reactome.org/PathwayBrowser/#/R-HSA-9845033 CLIP1-LTK promotes MAPK1 and MAPK3 phosphorylation TAS Homo sapiens 30616 R-HSA-9851078 https://reactome.org/PathwayBrowser/#/R-HSA-9851078 NPM1-ALK-dependent MAPK8,9 phosphorylation TAS Homo sapiens 30616 R-HSA-9851096 https://reactome.org/PathwayBrowser/#/R-HSA-9851096 NPM1-ALK- and JNK-dependent JUN phosphorylation TAS Homo sapiens 30616 R-HSA-9851102 https://reactome.org/PathwayBrowser/#/R-HSA-9851102 NPM1-ALK- and PI3K-dependent MDM2 phosphorylation TAS Homo sapiens 30616 R-HSA-9851114 https://reactome.org/PathwayBrowser/#/R-HSA-9851114 NPM1-ALK-dependent TYK2 phosphorylation TAS Homo sapiens 30616 R-HSA-9851142 https://reactome.org/PathwayBrowser/#/R-HSA-9851142 TYK2-dependent STAT1 and STAT3 phosphorylation TAS Homo sapiens 30616 R-HSA-9851972 https://reactome.org/PathwayBrowser/#/R-HSA-9851972 PLK1 phosphorylates FIRRM at S43 TAS Homo sapiens 30616 R-HSA-9853369 https://reactome.org/PathwayBrowser/#/R-HSA-9853369 PLK1 phosphorylates FIRMM at S744 TAS Homo sapiens 30616 R-HSA-9861642 https://reactome.org/PathwayBrowser/#/R-HSA-9861642 NEK1 phosphorylates ME1 TAS Homo sapiens 30616 R-HSA-990526 https://reactome.org/PathwayBrowser/#/R-HSA-990526 Recruitment of ITCH and K48 ubiquitination of MAVS TAS Homo sapiens 30616 R-HSA-990528 https://reactome.org/PathwayBrowser/#/R-HSA-990528 Interaction of PCBP2 with MAVS TAS Homo sapiens 30616 R-HSA-994137 https://reactome.org/PathwayBrowser/#/R-HSA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 TAS Homo sapiens 30616 R-HSA-994140 https://reactome.org/PathwayBrowser/#/R-HSA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 TAS Homo sapiens 30616 R-HSA-997381 https://reactome.org/PathwayBrowser/#/R-HSA-997381 TDPK phosphorylates ThDP to ThTP TAS Homo sapiens 30616 R-MGA-5672766 https://reactome.org/PathwayBrowser/#/R-MGA-5672766 Turkey MYLK phosphorylates MRLCs of the non-muscle myosin II complex TAS Meleagris gallopavo 30616 R-MMU-109624 https://reactome.org/PathwayBrowser/#/R-MMU-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Mus musculus 30616 R-MMU-109671 https://reactome.org/PathwayBrowser/#/R-MMU-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Mus musculus 30616 R-MMU-109699 https://reactome.org/PathwayBrowser/#/R-MMU-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-109702 https://reactome.org/PathwayBrowser/#/R-MMU-109702 PDPK1 phosphorylates AKT2 IEA Mus musculus 30616 R-MMU-109759 https://reactome.org/PathwayBrowser/#/R-MMU-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Mus musculus 30616 R-MMU-109822 https://reactome.org/PathwayBrowser/#/R-MMU-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Mus musculus 30616 R-MMU-109823 https://reactome.org/PathwayBrowser/#/R-MMU-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Mus musculus 30616 R-MMU-109860 https://reactome.org/PathwayBrowser/#/R-MMU-109860 MAP2K1 phosphorylates MAPK3 IEA Mus musculus 30616 R-MMU-109862 https://reactome.org/PathwayBrowser/#/R-MMU-109862 MAP2K2 phosphorylates MAPK1 IEA Mus musculus 30616 R-MMU-109903 https://reactome.org/PathwayBrowser/#/R-MMU-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Mus musculus 30616 R-MMU-110133 https://reactome.org/PathwayBrowser/#/R-MMU-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Mus musculus 30616 R-MMU-110137 https://reactome.org/PathwayBrowser/#/R-MMU-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Mus musculus 30616 R-MMU-110138 https://reactome.org/PathwayBrowser/#/R-MMU-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 30616 R-MMU-110141 https://reactome.org/PathwayBrowser/#/R-MMU-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Mus musculus 30616 R-MMU-110144 https://reactome.org/PathwayBrowser/#/R-MMU-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Mus musculus 30616 R-MMU-110145 https://reactome.org/PathwayBrowser/#/R-MMU-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Mus musculus 30616 R-MMU-1112510 https://reactome.org/PathwayBrowser/#/R-MMU-1112510 IL6ST is tyrosine phosphorylated IEA Mus musculus 30616 R-MMU-1112514 https://reactome.org/PathwayBrowser/#/R-MMU-1112514 JAK activation IEA Mus musculus 30616 R-MMU-1112602 https://reactome.org/PathwayBrowser/#/R-MMU-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Mus musculus 30616 R-MMU-1112703 https://reactome.org/PathwayBrowser/#/R-MMU-1112703 PTPN11 is phosphorylated IEA Mus musculus 30616 R-MMU-1112727 https://reactome.org/PathwayBrowser/#/R-MMU-1112727 Serine phosphorylation of STATs IEA Mus musculus 30616 R-MMU-111742 https://reactome.org/PathwayBrowser/#/R-MMU-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 30616 R-MMU-111751 https://reactome.org/PathwayBrowser/#/R-MMU-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 30616 R-MMU-111804 https://reactome.org/PathwayBrowser/#/R-MMU-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 30616 R-MMU-111898 https://reactome.org/PathwayBrowser/#/R-MMU-111898 Phosphorylation of cPLA2 by ERK-2 IEA Mus musculus 30616 R-MMU-111915 https://reactome.org/PathwayBrowser/#/R-MMU-111915 CAMK4 autophosphorylates IEA Mus musculus 30616 R-MMU-111930 https://reactome.org/PathwayBrowser/#/R-MMU-111930 Adenylate cyclase produces cAMP IEA Mus musculus 30616 R-MMU-111970 https://reactome.org/PathwayBrowser/#/R-MMU-111970 PKC phosphorylates GRK2 IEA Mus musculus 30616 R-MMU-112342 https://reactome.org/PathwayBrowser/#/R-MMU-112342 Inactivation of MAP2K1 by CDK1 IEA Mus musculus 30616 R-MMU-112381 https://reactome.org/PathwayBrowser/#/R-MMU-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Mus musculus 30616 R-MMU-114252 https://reactome.org/PathwayBrowser/#/R-MMU-114252 Cleavage of Procaspase-3 by the apoptosome IEA Mus musculus 30616 R-MMU-114254 https://reactome.org/PathwayBrowser/#/R-MMU-114254 CYCS binds to APAF1 IEA Mus musculus 30616 R-MMU-114256 https://reactome.org/PathwayBrowser/#/R-MMU-114256 CYCS:APAF1 binds procaspase-9 IEA Mus musculus 30616 R-MMU-114261 https://reactome.org/PathwayBrowser/#/R-MMU-114261 Cleavage of Procaspase-7 by the apoptosome IEA Mus musculus 30616 R-MMU-114600 https://reactome.org/PathwayBrowser/#/R-MMU-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Mus musculus 30616 R-MMU-114683 https://reactome.org/PathwayBrowser/#/R-MMU-114683 Phosphorylation of Platelet Sec-1 IEA Mus musculus 30616 R-MMU-114684 https://reactome.org/PathwayBrowser/#/R-MMU-114684 Phosphorylation of Syntaxin-4 IEA Mus musculus 30616 R-MMU-1168459 https://reactome.org/PathwayBrowser/#/R-MMU-1168459 Lyn activates ERK IEA Mus musculus 30616 R-MMU-1168635 https://reactome.org/PathwayBrowser/#/R-MMU-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Mus musculus 30616 R-MMU-1168638 https://reactome.org/PathwayBrowser/#/R-MMU-1168638 Activated IKK phosphorylates I-kappaB IEA Mus musculus 30616 R-MMU-1168923 https://reactome.org/PathwayBrowser/#/R-MMU-1168923 Stat5 tyrosine phosphorylation TAS Mus musculus 30616 R-MMU-1169206 https://reactome.org/PathwayBrowser/#/R-MMU-1169206 Jak2 phosphorylates Stat1/Stat3 TAS Mus musculus 30616 R-MMU-1169394 https://reactome.org/PathwayBrowser/#/R-MMU-1169394 ISGylation of IRF3 IEA Mus musculus 30616 R-MMU-1169397 https://reactome.org/PathwayBrowser/#/R-MMU-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Mus musculus 30616 R-MMU-1169398 https://reactome.org/PathwayBrowser/#/R-MMU-1169398 ISGylation of host protein filamin B IEA Mus musculus 30616 R-MMU-1169402 https://reactome.org/PathwayBrowser/#/R-MMU-1169402 ISGylation of E2 conjugating enzymes IEA Mus musculus 30616 R-MMU-1169405 https://reactome.org/PathwayBrowser/#/R-MMU-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Mus musculus 30616 R-MMU-1169406 https://reactome.org/PathwayBrowser/#/R-MMU-1169406 ISGylation of host proteins IEA Mus musculus 30616 R-MMU-1169494 https://reactome.org/PathwayBrowser/#/R-MMU-1169494 Rasgrp1 and Rasgrp3 are recruited to the membrane and phosphorylated TAS Mus musculus 30616 R-MMU-1181149 https://reactome.org/PathwayBrowser/#/R-MMU-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Mus musculus 30616 R-MMU-1226094 https://reactome.org/PathwayBrowser/#/R-MMU-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Mus musculus 30616 R-MMU-1226095 https://reactome.org/PathwayBrowser/#/R-MMU-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Mus musculus 30616 R-MMU-1247935 https://reactome.org/PathwayBrowser/#/R-MMU-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Mus musculus 30616 R-MMU-1247960 https://reactome.org/PathwayBrowser/#/R-MMU-1247960 Activation of p38 MAPK IEA Mus musculus 30616 R-MMU-1250195 https://reactome.org/PathwayBrowser/#/R-MMU-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Mus musculus 30616 R-MMU-1250315 https://reactome.org/PathwayBrowser/#/R-MMU-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Mus musculus 30616 R-MMU-1250348 https://reactome.org/PathwayBrowser/#/R-MMU-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Mus musculus 30616 R-MMU-1250370 https://reactome.org/PathwayBrowser/#/R-MMU-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Mus musculus 30616 R-MMU-1250462 https://reactome.org/PathwayBrowser/#/R-MMU-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Mus musculus 30616 R-MMU-1295540 https://reactome.org/PathwayBrowser/#/R-MMU-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Mus musculus 30616 R-MMU-1295609 https://reactome.org/PathwayBrowser/#/R-MMU-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Mus musculus 30616 R-MMU-1295764 https://reactome.org/PathwayBrowser/#/R-MMU-1295764 IL7r is phosphorylated on Y449 TAS Mus musculus 30616 R-MMU-1296024 https://reactome.org/PathwayBrowser/#/R-MMU-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Mus musculus 30616 R-MMU-1306957 https://reactome.org/PathwayBrowser/#/R-MMU-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Mus musculus 30616 R-MMU-1306979 https://reactome.org/PathwayBrowser/#/R-MMU-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Mus musculus 30616 R-MMU-1307963 https://reactome.org/PathwayBrowser/#/R-MMU-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Mus musculus 30616 R-MMU-1358791 https://reactome.org/PathwayBrowser/#/R-MMU-1358791 Phosphorylation of USP8 by P-AKT IEA Mus musculus 30616 R-MMU-1362270 https://reactome.org/PathwayBrowser/#/R-MMU-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Mus musculus 30616 R-MMU-1369028 https://reactome.org/PathwayBrowser/#/R-MMU-1369028 ABCAs mediate lipid efflux IEA Mus musculus 30616 R-MMU-1369052 https://reactome.org/PathwayBrowser/#/R-MMU-1369052 ABCAs mediate lipid influx IEA Mus musculus 30616 R-MMU-1369065 https://reactome.org/PathwayBrowser/#/R-MMU-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Mus musculus 30616 R-MMU-1370505 https://reactome.org/PathwayBrowser/#/R-MMU-1370505 PRLR is phosphorylated at Ser-349 IEA Mus musculus 30616 R-MMU-139855 https://reactome.org/PathwayBrowser/#/R-MMU-139855 P2X1-mediated entry of Ca++ from plasma IEA Mus musculus 30616 R-MMU-139908 https://reactome.org/PathwayBrowser/#/R-MMU-139908 Phosphorylation of DLC2 by MAPK8 IEA Mus musculus 30616 R-MMU-139918 https://reactome.org/PathwayBrowser/#/R-MMU-139918 Phosphorylation of BIM by JNK IEA Mus musculus 30616 R-MMU-1433418 https://reactome.org/PathwayBrowser/#/R-MMU-1433418 Phosphorylation of JAK2 IEA Mus musculus 30616 R-MMU-1433454 https://reactome.org/PathwayBrowser/#/R-MMU-1433454 Phosphorylation of GAB2 by SFKs IEA Mus musculus 30616 R-MMU-1433488 https://reactome.org/PathwayBrowser/#/R-MMU-1433488 Phosphorylation of SHP2 by SFKs IEA Mus musculus 30616 R-MMU-1433506 https://reactome.org/PathwayBrowser/#/R-MMU-1433506 Phosphorylation of APS IEA Mus musculus 30616 R-MMU-1433508 https://reactome.org/PathwayBrowser/#/R-MMU-1433508 PKC alpha interacts with and phosphorylates KIT IEA Mus musculus 30616 R-MMU-1433514 https://reactome.org/PathwayBrowser/#/R-MMU-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Mus musculus 30616 R-MMU-1433542 https://reactome.org/PathwayBrowser/#/R-MMU-1433542 Phosphorylation and activation of VAV1 IEA Mus musculus 30616 R-MMU-1449573 https://reactome.org/PathwayBrowser/#/R-MMU-1449573 Fusion of Glut4 Vesicle with the Plasma Membrane TAS Mus musculus 30616 R-MMU-1449591 https://reactome.org/PathwayBrowser/#/R-MMU-1449591 Akt2 Phosphorylates Myosin 5a TAS Mus musculus 30616 R-MMU-1454711 https://reactome.org/PathwayBrowser/#/R-MMU-1454711 Ampk-alpha2 Phosphorylates Tbc1d1 TAS Mus musculus 30616 R-MMU-1454916 https://reactome.org/PathwayBrowser/#/R-MMU-1454916 The ABCC family mediates organic anion transport IEA Mus musculus 30616 R-MMU-1454928 https://reactome.org/PathwayBrowser/#/R-MMU-1454928 ABCG4 may mediate cholesterol efflux IEA Mus musculus 30616 R-MMU-1458507 https://reactome.org/PathwayBrowser/#/R-MMU-1458507 Akt2 Phosphorylates Rgc2 TAS Mus musculus 30616 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-1467466 https://reactome.org/PathwayBrowser/#/R-MMU-1467466 ABCA4 mediates atRAL transport IEA Mus musculus 30616 R-MMU-1470009 https://reactome.org/PathwayBrowser/#/R-MMU-1470009 Phosphorylation of STATs IEA Mus musculus 30616 R-MMU-1472121 https://reactome.org/PathwayBrowser/#/R-MMU-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Mus musculus 30616 R-MMU-1475422 https://reactome.org/PathwayBrowser/#/R-MMU-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Mus musculus 30616 R-MMU-1483004 https://reactome.org/PathwayBrowser/#/R-MMU-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Mus musculus 30616 R-MMU-1483222 https://reactome.org/PathwayBrowser/#/R-MMU-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Mus musculus 30616 R-MMU-1497853 https://reactome.org/PathwayBrowser/#/R-MMU-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Mus musculus 30616 R-MMU-1524186 https://reactome.org/PathwayBrowser/#/R-MMU-1524186 Phosphorylation of PLCgamma by PDGFR IEA Mus musculus 30616 R-MMU-1549526 https://reactome.org/PathwayBrowser/#/R-MMU-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Mus musculus 30616 R-MMU-156673 https://reactome.org/PathwayBrowser/#/R-MMU-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Mus musculus 30616 R-MMU-156678 https://reactome.org/PathwayBrowser/#/R-MMU-156678 Activation of Cdc25C IEA Mus musculus 30616 R-MMU-156682 https://reactome.org/PathwayBrowser/#/R-MMU-156682 PLK1 phosphorylates NUDC IEA Mus musculus 30616 R-MMU-156699 https://reactome.org/PathwayBrowser/#/R-MMU-156699 Inactivation of Wee1 kinase IEA Mus musculus 30616 R-MMU-156723 https://reactome.org/PathwayBrowser/#/R-MMU-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Mus musculus 30616 R-MMU-159101 https://reactome.org/PathwayBrowser/#/R-MMU-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Mus musculus 30616 R-MMU-159425 https://reactome.org/PathwayBrowser/#/R-MMU-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 30616 R-MMU-159443 https://reactome.org/PathwayBrowser/#/R-MMU-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Mus musculus 30616 R-MMU-159567 https://reactome.org/PathwayBrowser/#/R-MMU-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Mus musculus 30616 R-MMU-1605464 https://reactome.org/PathwayBrowser/#/R-MMU-1605464 p38 Mapk phosphorylates Ppargc1a TAS Mus musculus 30616 R-MMU-1605475 https://reactome.org/PathwayBrowser/#/R-MMU-1605475 Ampk phosphorylates Ppargc1a TAS Mus musculus 30616 R-MMU-162352 https://reactome.org/PathwayBrowser/#/R-MMU-162352 Phosphorylation of PDE3B by AKT-1 TAS Mus musculus 30616 R-MMU-162657 https://reactome.org/PathwayBrowser/#/R-MMU-162657 Inactivation of Myt1 kinase IEA Mus musculus 30616 R-MMU-163010 https://reactome.org/PathwayBrowser/#/R-MMU-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Mus musculus 30616 R-MMU-163120 https://reactome.org/PathwayBrowser/#/R-MMU-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Mus musculus 30616 R-MMU-163215 https://reactome.org/PathwayBrowser/#/R-MMU-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Mus musculus 30616 R-MMU-1632857 https://reactome.org/PathwayBrowser/#/R-MMU-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Mus musculus 30616 R-MMU-163422 https://reactome.org/PathwayBrowser/#/R-MMU-163422 perilipin + 3 ATP -> phosphorylated perilipin + 3 ADP TAS Mus musculus 30616 R-MMU-1638803 https://reactome.org/PathwayBrowser/#/R-MMU-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Mus musculus 30616 R-MMU-1638845 https://reactome.org/PathwayBrowser/#/R-MMU-1638845 CERK phosphorylates CERA to form C1P IEA Mus musculus 30616 R-MMU-164832 https://reactome.org/PathwayBrowser/#/R-MMU-164832 ATPase synthesizes ATP IEA Mus musculus 30616 R-MMU-164834 https://reactome.org/PathwayBrowser/#/R-MMU-164834 Enzyme-bound ATP is released IEA Mus musculus 30616 R-MMU-165162 https://reactome.org/PathwayBrowser/#/R-MMU-165162 Phosphorylation of TSC2 by PKB IEA Mus musculus 30616 R-MMU-165182 https://reactome.org/PathwayBrowser/#/R-MMU-165182 Phosphorylation of complexed TSC2 by PKB IEA Mus musculus 30616 R-MMU-165692 https://reactome.org/PathwayBrowser/#/R-MMU-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Mus musculus 30616 R-MMU-165718 https://reactome.org/PathwayBrowser/#/R-MMU-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Mus musculus 30616 R-MMU-165726 https://reactome.org/PathwayBrowser/#/R-MMU-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Mus musculus 30616 R-MMU-165758 https://reactome.org/PathwayBrowser/#/R-MMU-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Mus musculus 30616 R-MMU-165766 https://reactome.org/PathwayBrowser/#/R-MMU-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Mus musculus 30616 R-MMU-165777 https://reactome.org/PathwayBrowser/#/R-MMU-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Mus musculus 30616 R-MMU-166245 https://reactome.org/PathwayBrowser/#/R-MMU-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Mus musculus 30616 R-MMU-1675773 https://reactome.org/PathwayBrowser/#/R-MMU-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Mus musculus 30616 R-MMU-1675776 https://reactome.org/PathwayBrowser/#/R-MMU-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Mus musculus 30616 R-MMU-1675780 https://reactome.org/PathwayBrowser/#/R-MMU-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Mus musculus 30616 R-MMU-1675810 https://reactome.org/PathwayBrowser/#/R-MMU-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Mus musculus 30616 R-MMU-1675813 https://reactome.org/PathwayBrowser/#/R-MMU-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Mus musculus 30616 R-MMU-1675883 https://reactome.org/PathwayBrowser/#/R-MMU-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Mus musculus 30616 R-MMU-1675928 https://reactome.org/PathwayBrowser/#/R-MMU-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Mus musculus 30616 R-MMU-1675939 https://reactome.org/PathwayBrowser/#/R-MMU-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Mus musculus 30616 R-MMU-1675961 https://reactome.org/PathwayBrowser/#/R-MMU-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Mus musculus 30616 R-MMU-1675974 https://reactome.org/PathwayBrowser/#/R-MMU-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Mus musculus 30616 R-MMU-1676024 https://reactome.org/PathwayBrowser/#/R-MMU-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Mus musculus 30616 R-MMU-1676048 https://reactome.org/PathwayBrowser/#/R-MMU-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Mus musculus 30616 R-MMU-1676082 https://reactome.org/PathwayBrowser/#/R-MMU-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Mus musculus 30616 R-MMU-1676109 https://reactome.org/PathwayBrowser/#/R-MMU-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Mus musculus 30616 R-MMU-1676134 https://reactome.org/PathwayBrowser/#/R-MMU-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Mus musculus 30616 R-MMU-1676145 https://reactome.org/PathwayBrowser/#/R-MMU-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Mus musculus 30616 R-MMU-1676185 https://reactome.org/PathwayBrowser/#/R-MMU-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Mus musculus 30616 R-MMU-1676206 https://reactome.org/PathwayBrowser/#/R-MMU-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Mus musculus 30616 R-MMU-1678923 https://reactome.org/PathwayBrowser/#/R-MMU-1678923 TLR folding by chaperones GP96 and CNPY3 IEA Mus musculus 30616 R-MMU-1678944 https://reactome.org/PathwayBrowser/#/R-MMU-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Mus musculus 30616 R-MMU-168053 https://reactome.org/PathwayBrowser/#/R-MMU-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Mus musculus 30616 R-MMU-168136 https://reactome.org/PathwayBrowser/#/R-MMU-168136 Activated JNKs phosphorylate c-JUN IEA Mus musculus 30616 R-MMU-168140 https://reactome.org/PathwayBrowser/#/R-MMU-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Mus musculus 30616 R-MMU-168162 https://reactome.org/PathwayBrowser/#/R-MMU-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Mus musculus 30616 R-MMU-169905 https://reactome.org/PathwayBrowser/#/R-MMU-169905 ARMS is phosphorylated by active TrkA receptor IEA Mus musculus 30616 R-MMU-170026 https://reactome.org/PathwayBrowser/#/R-MMU-170026 Protons are translocated from the intermembrane space to the matrix IEA Mus musculus 30616 R-MMU-170055 https://reactome.org/PathwayBrowser/#/R-MMU-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Mus musculus 30616 R-MMU-170070 https://reactome.org/PathwayBrowser/#/R-MMU-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Mus musculus 30616 R-MMU-170076 https://reactome.org/PathwayBrowser/#/R-MMU-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Mus musculus 30616 R-MMU-170087 https://reactome.org/PathwayBrowser/#/R-MMU-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Mus musculus 30616 R-MMU-170126 https://reactome.org/PathwayBrowser/#/R-MMU-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Mus musculus 30616 R-MMU-170676 https://reactome.org/PathwayBrowser/#/R-MMU-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Mus musculus 30616 R-MMU-170843 https://reactome.org/PathwayBrowser/#/R-MMU-170843 TGFBR2 phosphorylates TGFBR1 IEA Mus musculus 30616 R-MMU-170868 https://reactome.org/PathwayBrowser/#/R-MMU-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Mus musculus 30616 R-MMU-170977 https://reactome.org/PathwayBrowser/#/R-MMU-170977 FRS2 is phosphorylated by active TrkA receptor IEA Mus musculus 30616 R-MMU-174079 https://reactome.org/PathwayBrowser/#/R-MMU-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Mus musculus 30616 R-MMU-174122 https://reactome.org/PathwayBrowser/#/R-MMU-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Mus musculus 30616 R-MMU-174164 https://reactome.org/PathwayBrowser/#/R-MMU-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Mus musculus 30616 R-MMU-174174 https://reactome.org/PathwayBrowser/#/R-MMU-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Mus musculus 30616 R-MMU-174251 https://reactome.org/PathwayBrowser/#/R-MMU-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Mus musculus 30616 R-MMU-174367 https://reactome.org/PathwayBrowser/#/R-MMU-174367 GCL ligates L-Glu to L-Cys IEA Mus musculus 30616 R-MMU-174389 https://reactome.org/PathwayBrowser/#/R-MMU-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Mus musculus 30616 R-MMU-174391 https://reactome.org/PathwayBrowser/#/R-MMU-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Mus musculus 30616 R-MMU-174392 https://reactome.org/PathwayBrowser/#/R-MMU-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Mus musculus 30616 R-MMU-174394 https://reactome.org/PathwayBrowser/#/R-MMU-174394 GSS:Mg2+ dimer synthesizes GSH IEA Mus musculus 30616 R-MMU-174438 https://reactome.org/PathwayBrowser/#/R-MMU-174438 Formation of the Flap Intermediate on the C-strand IEA Mus musculus 30616 R-MMU-174439 https://reactome.org/PathwayBrowser/#/R-MMU-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Mus musculus 30616 R-MMU-176116 https://reactome.org/PathwayBrowser/#/R-MMU-176116 Recruitment and activation of Chk1 IEA Mus musculus 30616 R-MMU-176298 https://reactome.org/PathwayBrowser/#/R-MMU-176298 Activation of claspin IEA Mus musculus 30616 R-MMU-177157 https://reactome.org/PathwayBrowser/#/R-MMU-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Mus musculus 30616 R-MMU-177275 https://reactome.org/PathwayBrowser/#/R-MMU-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Mus musculus 30616 R-MMU-177284 https://reactome.org/PathwayBrowser/#/R-MMU-177284 PKA phosphorylates PDE4B IEA Mus musculus 30616 R-MMU-177930 https://reactome.org/PathwayBrowser/#/R-MMU-177930 GAB1 phosphorylation by EGFR kinase IEA Mus musculus 30616 R-MMU-177933 https://reactome.org/PathwayBrowser/#/R-MMU-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Mus musculus 30616 R-MMU-177934 https://reactome.org/PathwayBrowser/#/R-MMU-177934 EGFR autophosphorylation IEA Mus musculus 30616 R-MMU-177937 https://reactome.org/PathwayBrowser/#/R-MMU-177937 Phosphorylation of EGFR by SRC kinase IEA Mus musculus 30616 R-MMU-177939 https://reactome.org/PathwayBrowser/#/R-MMU-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Mus musculus 30616 R-MMU-1810473 https://reactome.org/PathwayBrowser/#/R-MMU-1810473 Recruitment Tbk1 to dsDNA:Dai followed by its activation TAS Mus musculus 30616 R-MMU-182969 https://reactome.org/PathwayBrowser/#/R-MMU-182969 Phosphorylation of CBL (EGFR:CBL) IEA Mus musculus 30616 R-MMU-183058 https://reactome.org/PathwayBrowser/#/R-MMU-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Mus musculus 30616 R-MMU-1855153 https://reactome.org/PathwayBrowser/#/R-MMU-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Mus musculus 30616 R-MMU-1855157 https://reactome.org/PathwayBrowser/#/R-MMU-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Mus musculus 30616 R-MMU-1855158 https://reactome.org/PathwayBrowser/#/R-MMU-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Mus musculus 30616 R-MMU-1855162 https://reactome.org/PathwayBrowser/#/R-MMU-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Mus musculus 30616 R-MMU-1855169 https://reactome.org/PathwayBrowser/#/R-MMU-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Mus musculus 30616 R-MMU-1855172 https://reactome.org/PathwayBrowser/#/R-MMU-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Mus musculus 30616 R-MMU-1855176 https://reactome.org/PathwayBrowser/#/R-MMU-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Mus musculus 30616 R-MMU-1855179 https://reactome.org/PathwayBrowser/#/R-MMU-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Mus musculus 30616 R-MMU-1855181 https://reactome.org/PathwayBrowser/#/R-MMU-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Mus musculus 30616 R-MMU-1855182 https://reactome.org/PathwayBrowser/#/R-MMU-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Mus musculus 30616 R-MMU-1855185 https://reactome.org/PathwayBrowser/#/R-MMU-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 30616 R-MMU-1855193 https://reactome.org/PathwayBrowser/#/R-MMU-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Mus musculus 30616 R-MMU-1855194 https://reactome.org/PathwayBrowser/#/R-MMU-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Mus musculus 30616 R-MMU-1855197 https://reactome.org/PathwayBrowser/#/R-MMU-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Mus musculus 30616 R-MMU-1855206 https://reactome.org/PathwayBrowser/#/R-MMU-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 30616 R-MMU-1855207 https://reactome.org/PathwayBrowser/#/R-MMU-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Mus musculus 30616 R-MMU-1855216 https://reactome.org/PathwayBrowser/#/R-MMU-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Mus musculus 30616 R-MMU-1855223 https://reactome.org/PathwayBrowser/#/R-MMU-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Mus musculus 30616 R-MMU-1855224 https://reactome.org/PathwayBrowser/#/R-MMU-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Mus musculus 30616 R-MMU-1855227 https://reactome.org/PathwayBrowser/#/R-MMU-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Mus musculus 30616 R-MMU-1855228 https://reactome.org/PathwayBrowser/#/R-MMU-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 30616 R-MMU-1855230 https://reactome.org/PathwayBrowser/#/R-MMU-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Mus musculus 30616 R-MMU-1855233 https://reactome.org/PathwayBrowser/#/R-MMU-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Mus musculus 30616 R-MMU-1861595 https://reactome.org/PathwayBrowser/#/R-MMU-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Mus musculus 30616 R-MMU-186786 https://reactome.org/PathwayBrowser/#/R-MMU-186786 Autophosphorylation of PDGF beta receptors IEA Mus musculus 30616 R-MMU-186800 https://reactome.org/PathwayBrowser/#/R-MMU-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-187520 https://reactome.org/PathwayBrowser/#/R-MMU-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Mus musculus 30616 R-MMU-187688 https://reactome.org/PathwayBrowser/#/R-MMU-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Mus musculus 30616 R-MMU-187916 https://reactome.org/PathwayBrowser/#/R-MMU-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Mus musculus 30616 R-MMU-187948 https://reactome.org/PathwayBrowser/#/R-MMU-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Mus musculus 30616 R-MMU-187949 https://reactome.org/PathwayBrowser/#/R-MMU-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Mus musculus 30616 R-MMU-187959 https://reactome.org/PathwayBrowser/#/R-MMU-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Mus musculus 30616 R-MMU-188350 https://reactome.org/PathwayBrowser/#/R-MMU-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Mus musculus 30616 R-MMU-188390 https://reactome.org/PathwayBrowser/#/R-MMU-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Mus musculus 30616 R-MMU-190326 https://reactome.org/PathwayBrowser/#/R-MMU-190326 Autocatalytic phosphorylation of FGFR4 IEA Mus musculus 30616 R-MMU-190385 https://reactome.org/PathwayBrowser/#/R-MMU-190385 Autocatalytic phosphorylation of FGFR3b IEA Mus musculus 30616 R-MMU-190388 https://reactome.org/PathwayBrowser/#/R-MMU-190388 Autocatalytic phosphorylation of FGFR3c IEA Mus musculus 30616 R-MMU-190408 https://reactome.org/PathwayBrowser/#/R-MMU-190408 Autocatalytic phosphorylation of FGFR2b IEA Mus musculus 30616 R-MMU-190413 https://reactome.org/PathwayBrowser/#/R-MMU-190413 Autocatalytic phosphorylation of FGFR2c IEA Mus musculus 30616 R-MMU-190427 https://reactome.org/PathwayBrowser/#/R-MMU-190427 Autocatalytic phosphorylation of FGFR1b IEA Mus musculus 30616 R-MMU-190429 https://reactome.org/PathwayBrowser/#/R-MMU-190429 Autocatalytic phosphorylation of FGFR1c IEA Mus musculus 30616 R-MMU-191062 https://reactome.org/PathwayBrowser/#/R-MMU-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Mus musculus 30616 R-MMU-191380 https://reactome.org/PathwayBrowser/#/R-MMU-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Mus musculus 30616 R-MMU-191414 https://reactome.org/PathwayBrowser/#/R-MMU-191414 MVD decarboxylates MVA5PP to IPPP IEA Mus musculus 30616 R-MMU-191422 https://reactome.org/PathwayBrowser/#/R-MMU-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Mus musculus 30616 R-MMU-191636 https://reactome.org/PathwayBrowser/#/R-MMU-191636 Phosphorylation of Cx43 by c-src IEA Mus musculus 30616 R-MMU-192137 https://reactome.org/PathwayBrowser/#/R-MMU-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 30616 R-MMU-193362 https://reactome.org/PathwayBrowser/#/R-MMU-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-193401 https://reactome.org/PathwayBrowser/#/R-MMU-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 30616 R-MMU-193407 https://reactome.org/PathwayBrowser/#/R-MMU-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 30616 R-MMU-193424 https://reactome.org/PathwayBrowser/#/R-MMU-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 30616 R-MMU-193703 https://reactome.org/PathwayBrowser/#/R-MMU-193703 IKKbeta is activated IEA Mus musculus 30616 R-MMU-193705 https://reactome.org/PathwayBrowser/#/R-MMU-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Mus musculus 30616 R-MMU-193711 https://reactome.org/PathwayBrowser/#/R-MMU-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 30616 R-MMU-193727 https://reactome.org/PathwayBrowser/#/R-MMU-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 30616 R-MMU-193743 https://reactome.org/PathwayBrowser/#/R-MMU-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 30616 R-MMU-193766 https://reactome.org/PathwayBrowser/#/R-MMU-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 30616 R-MMU-194153 https://reactome.org/PathwayBrowser/#/R-MMU-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-195275 https://reactome.org/PathwayBrowser/#/R-MMU-195275 Phosphorylation of APC component of the destruction complex IEA Mus musculus 30616 R-MMU-195283 https://reactome.org/PathwayBrowser/#/R-MMU-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Mus musculus 30616 R-MMU-195287 https://reactome.org/PathwayBrowser/#/R-MMU-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Mus musculus 30616 R-MMU-195300 https://reactome.org/PathwayBrowser/#/R-MMU-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Mus musculus 30616 R-MMU-195318 https://reactome.org/PathwayBrowser/#/R-MMU-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Mus musculus 30616 R-MMU-1963581 https://reactome.org/PathwayBrowser/#/R-MMU-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Mus musculus 30616 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 30616 R-MMU-1963586 https://reactome.org/PathwayBrowser/#/R-MMU-1963586 SRC family kinases phosphorylate ERBB2 IEA Mus musculus 30616 R-MMU-196753 https://reactome.org/PathwayBrowser/#/R-MMU-196753 2xPPCS ligates PPanK with Cys IEA Mus musculus 30616 R-MMU-196754 https://reactome.org/PathwayBrowser/#/R-MMU-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Mus musculus 30616 R-MMU-196761 https://reactome.org/PathwayBrowser/#/R-MMU-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Mus musculus 30616 R-MMU-196773 https://reactome.org/PathwayBrowser/#/R-MMU-196773 COASY phosphorylates DP-CoA IEA Mus musculus 30616 R-MMU-196857 https://reactome.org/PathwayBrowser/#/R-MMU-196857 PANK2 phosphorylates PanK IEA Mus musculus 30616 R-MMU-196929 https://reactome.org/PathwayBrowser/#/R-MMU-196929 FLAD1 phosphorylates FMN IEA Mus musculus 30616 R-MMU-196964 https://reactome.org/PathwayBrowser/#/R-MMU-196964 RFK:Mg2+ phosphorylates RIB IEA Mus musculus 30616 R-MMU-197198 https://reactome.org/PathwayBrowser/#/R-MMU-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Mus musculus 30616 R-MMU-197235 https://reactome.org/PathwayBrowser/#/R-MMU-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 30616 R-MMU-197271 https://reactome.org/PathwayBrowser/#/R-MMU-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Mus musculus 30616 R-MMU-197958 https://reactome.org/PathwayBrowser/#/R-MMU-197958 FPGS-2 transforms THF to THFPG IEA Mus musculus 30616 R-MMU-198263 https://reactome.org/PathwayBrowser/#/R-MMU-198263 NTRK1 phosphorylates IRS TAS Mus musculus 30616 R-MMU-198266 https://reactome.org/PathwayBrowser/#/R-MMU-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Mus musculus 30616 R-MMU-198314 https://reactome.org/PathwayBrowser/#/R-MMU-198314 DAG stimulates protein kinase C-delta IEA Mus musculus 30616 R-MMU-198599 https://reactome.org/PathwayBrowser/#/R-MMU-198599 AKT phosphorylates MDM2 IEA Mus musculus 30616 R-MMU-198609 https://reactome.org/PathwayBrowser/#/R-MMU-198609 AKT phosphorylates TSC2, inhibiting it IEA Mus musculus 30616 R-MMU-198611 https://reactome.org/PathwayBrowser/#/R-MMU-198611 AKT phosphorylates IKKalpha IEA Mus musculus 30616 R-MMU-198613 https://reactome.org/PathwayBrowser/#/R-MMU-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Mus musculus 30616 R-MMU-198621 https://reactome.org/PathwayBrowser/#/R-MMU-198621 AKT phosphorylates caspase-9 IEA Mus musculus 30616 R-MMU-198640 https://reactome.org/PathwayBrowser/#/R-MMU-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Mus musculus 30616 R-MMU-198669 https://reactome.org/PathwayBrowser/#/R-MMU-198669 p38MAPK phosphorylates MSK1 IEA Mus musculus 30616 R-MMU-198706 https://reactome.org/PathwayBrowser/#/R-MMU-198706 ERK1/2 activates ELK1 TAS Mus musculus 30616 R-MMU-198746 https://reactome.org/PathwayBrowser/#/R-MMU-198746 ERK1/2/5 activate RSK1/2/3 IEA Mus musculus 30616 R-MMU-198756 https://reactome.org/PathwayBrowser/#/R-MMU-198756 ERK1/2 phosphorylates MSK1 IEA Mus musculus 30616 R-MMU-199203 https://reactome.org/PathwayBrowser/#/R-MMU-199203 PANK1/3 phosphorylate PanK IEA Mus musculus 30616 R-MMU-199298 https://reactome.org/PathwayBrowser/#/R-MMU-199298 AKT phosphorylates CREB1 IEA Mus musculus 30616 R-MMU-199299 https://reactome.org/PathwayBrowser/#/R-MMU-199299 AKT phosphorylates FOXO transcription factors IEA Mus musculus 30616 R-MMU-199839 https://reactome.org/PathwayBrowser/#/R-MMU-199839 AKT can phosphorylate RSK IEA Mus musculus 30616 R-MMU-199863 https://reactome.org/PathwayBrowser/#/R-MMU-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Mus musculus 30616 R-MMU-199895 https://reactome.org/PathwayBrowser/#/R-MMU-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Mus musculus 30616 R-MMU-199910 https://reactome.org/PathwayBrowser/#/R-MMU-199910 MSK1 activates ATF1 IEA Mus musculus 30616 R-MMU-199917 https://reactome.org/PathwayBrowser/#/R-MMU-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Mus musculus 30616 R-MMU-199935 https://reactome.org/PathwayBrowser/#/R-MMU-199935 MSK1 activates CREB IEA Mus musculus 30616 R-MMU-200143 https://reactome.org/PathwayBrowser/#/R-MMU-200143 AKT phosphorylates AKT1S1 (PRAS40) IEA Mus musculus 30616 R-MMU-200318 https://reactome.org/PathwayBrowser/#/R-MMU-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Mus musculus 30616 R-MMU-200326 https://reactome.org/PathwayBrowser/#/R-MMU-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Mus musculus 30616 R-MMU-200421 https://reactome.org/PathwayBrowser/#/R-MMU-200421 Activation of cytosolic AMPK by phosphorylation IEA Mus musculus 30616 R-MMU-200423 https://reactome.org/PathwayBrowser/#/R-MMU-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Mus musculus 30616 R-MMU-200474 https://reactome.org/PathwayBrowser/#/R-MMU-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 30616 R-MMU-200512 https://reactome.org/PathwayBrowser/#/R-MMU-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 30616 R-MMU-200555 https://reactome.org/PathwayBrowser/#/R-MMU-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Mus musculus 30616 R-MMU-200681 https://reactome.org/PathwayBrowser/#/R-MMU-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Mus musculus 30616 R-MMU-200682 https://reactome.org/PathwayBrowser/#/R-MMU-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Mus musculus 30616 R-MMU-200711 https://reactome.org/PathwayBrowser/#/R-MMU-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Mus musculus 30616 R-MMU-201035 https://reactome.org/PathwayBrowser/#/R-MMU-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Mus musculus 30616 R-MMU-201443 https://reactome.org/PathwayBrowser/#/R-MMU-201443 Type II receptor phosphorylates type I receptor IEA Mus musculus 30616 R-MMU-201476 https://reactome.org/PathwayBrowser/#/R-MMU-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Mus musculus 30616 R-MMU-201510 https://reactome.org/PathwayBrowser/#/R-MMU-201510 PI3K synthesizes PIP3 downstream of ALK IEA Mus musculus 30616 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 30616 R-MMU-201677 https://reactome.org/PathwayBrowser/#/R-MMU-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Mus musculus 30616 R-MMU-201717 https://reactome.org/PathwayBrowser/#/R-MMU-201717 CSNK2-mediated phosphorylation of DVL IEA Mus musculus 30616 R-MMU-202111 https://reactome.org/PathwayBrowser/#/R-MMU-202111 AKT1 phosphorylates eNOS IEA Mus musculus 30616 R-MMU-202165 https://reactome.org/PathwayBrowser/#/R-MMU-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Mus musculus 30616 R-MMU-202168 https://reactome.org/PathwayBrowser/#/R-MMU-202168 Phosphorylation of ZAP-70 by Lck IEA Mus musculus 30616 R-MMU-202174 https://reactome.org/PathwayBrowser/#/R-MMU-202174 Activation of ZAP-70 IEA Mus musculus 30616 R-MMU-202216 https://reactome.org/PathwayBrowser/#/R-MMU-202216 Phosphorylation of SLP-76 IEA Mus musculus 30616 R-MMU-202222 https://reactome.org/PathwayBrowser/#/R-MMU-202222 Phosphorylation of PKC theta IEA Mus musculus 30616 R-MMU-202233 https://reactome.org/PathwayBrowser/#/R-MMU-202233 Inactivation of Lck by Csk IEA Mus musculus 30616 R-MMU-202245 https://reactome.org/PathwayBrowser/#/R-MMU-202245 Phosphorylation of TBSMs in LAT IEA Mus musculus 30616 R-MMU-202248 https://reactome.org/PathwayBrowser/#/R-MMU-202248 Phosphorylation of PLC-gamma1 IEA Mus musculus 30616 R-MMU-202291 https://reactome.org/PathwayBrowser/#/R-MMU-202291 Activation of Lck IEA Mus musculus 30616 R-MMU-202307 https://reactome.org/PathwayBrowser/#/R-MMU-202307 Change of PKC theta conformation IEA Mus musculus 30616 R-MMU-202365 https://reactome.org/PathwayBrowser/#/R-MMU-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-202437 https://reactome.org/PathwayBrowser/#/R-MMU-202437 Phosphorylation of CARMA1 IEA Mus musculus 30616 R-MMU-202459 https://reactome.org/PathwayBrowser/#/R-MMU-202459 Phosphorylation of Bcl10 IEA Mus musculus 30616 R-MMU-202500 https://reactome.org/PathwayBrowser/#/R-MMU-202500 Activation of IKK complex IEA Mus musculus 30616 R-MMU-202510 https://reactome.org/PathwayBrowser/#/R-MMU-202510 Activation of TAK1-TAB2 complex IEA Mus musculus 30616 R-MMU-202541 https://reactome.org/PathwayBrowser/#/R-MMU-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Mus musculus 30616 R-MMU-2028284 https://reactome.org/PathwayBrowser/#/R-MMU-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Mus musculus 30616 R-MMU-2028555 https://reactome.org/PathwayBrowser/#/R-MMU-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Mus musculus 30616 R-MMU-2028583 https://reactome.org/PathwayBrowser/#/R-MMU-2028583 Phosphorylation of YAP by LATS2 IEA Mus musculus 30616 R-MMU-2028589 https://reactome.org/PathwayBrowser/#/R-MMU-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Mus musculus 30616 R-MMU-2028591 https://reactome.org/PathwayBrowser/#/R-MMU-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Mus musculus 30616 R-MMU-2028598 https://reactome.org/PathwayBrowser/#/R-MMU-2028598 Phosphorylation of YAP by LATS1 IEA Mus musculus 30616 R-MMU-2028629 https://reactome.org/PathwayBrowser/#/R-MMU-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Mus musculus 30616 R-MMU-2028635 https://reactome.org/PathwayBrowser/#/R-MMU-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Mus musculus 30616 R-MMU-2028661 https://reactome.org/PathwayBrowser/#/R-MMU-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Mus musculus 30616 R-MMU-2028670 https://reactome.org/PathwayBrowser/#/R-MMU-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Mus musculus 30616 R-MMU-2028673 https://reactome.org/PathwayBrowser/#/R-MMU-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Mus musculus 30616 R-MMU-2028675 https://reactome.org/PathwayBrowser/#/R-MMU-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Mus musculus 30616 R-MMU-2028679 https://reactome.org/PathwayBrowser/#/R-MMU-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Mus musculus 30616 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus 30616 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus 30616 R-MMU-2029454 https://reactome.org/PathwayBrowser/#/R-MMU-2029454 Autophosphorylation of PAK1 IEA Mus musculus 30616 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus 30616 R-MMU-2029460 https://reactome.org/PathwayBrowser/#/R-MMU-2029460 PAK1 phosphorylates LIMK1 IEA Mus musculus 30616 R-MMU-2029466 https://reactome.org/PathwayBrowser/#/R-MMU-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Mus musculus 30616 R-MMU-2029469 https://reactome.org/PathwayBrowser/#/R-MMU-2029469 p-ERK phosphorylates WAVEs and ABI IEA Mus musculus 30616 R-MMU-2029473 https://reactome.org/PathwayBrowser/#/R-MMU-2029473 Branching and elongation of mother and daughter filaments IEA Mus musculus 30616 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus 30616 R-MMU-203070 https://reactome.org/PathwayBrowser/#/R-MMU-203070 Association of profilin with monomeric actin IEA Mus musculus 30616 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 30616 R-MMU-2046085 https://reactome.org/PathwayBrowser/#/R-MMU-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Mus musculus 30616 R-MMU-2046087 https://reactome.org/PathwayBrowser/#/R-MMU-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Mus musculus 30616 R-MMU-2046093 https://reactome.org/PathwayBrowser/#/R-MMU-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Mus musculus 30616 R-MMU-2046098 https://reactome.org/PathwayBrowser/#/R-MMU-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Mus musculus 30616 R-MMU-205060 https://reactome.org/PathwayBrowser/#/R-MMU-205060 NRIF and TRAF6 may activate JNK TAS Mus musculus 30616 R-MMU-205075 https://reactome.org/PathwayBrowser/#/R-MMU-205075 JNK phosphorylates BIM, BAD and other targets IEA Mus musculus 30616 R-MMU-205136 https://reactome.org/PathwayBrowser/#/R-MMU-205136 GTP-bound RAC contributes to JNK activation IEA Mus musculus 30616 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 30616 R-MMU-2060328 https://reactome.org/PathwayBrowser/#/R-MMU-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Mus musculus 30616 R-MMU-209087 https://reactome.org/PathwayBrowser/#/R-MMU-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Mus musculus 30616 R-MMU-209329 https://reactome.org/PathwayBrowser/#/R-MMU-209329 Murine MKK4 kinase is phosphorylated and activated by Phospho TAK1:Phospho TAB1:Phospho TAB2 kinase complex TAS Mus musculus 30616 R-MMU-210291 https://reactome.org/PathwayBrowser/#/R-MMU-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Mus musculus 30616 R-MMU-211119 https://reactome.org/PathwayBrowser/#/R-MMU-211119 Trans-phosphorylation of Tie2 TAS Mus musculus 30616 R-MMU-211164 https://reactome.org/PathwayBrowser/#/R-MMU-211164 AKT phosphorylates FOXO1A IEA Mus musculus 30616 R-MMU-212710 https://reactome.org/PathwayBrowser/#/R-MMU-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Mus musculus 30616 R-MMU-2130194 https://reactome.org/PathwayBrowser/#/R-MMU-2130194 ABL phosphorylates WAVEs IEA Mus musculus 30616 R-MMU-2161526 https://reactome.org/PathwayBrowser/#/R-MMU-2161526 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 30616 R-MMU-2161533 https://reactome.org/PathwayBrowser/#/R-MMU-2161533 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 30616 R-MMU-216723 https://reactome.org/PathwayBrowser/#/R-MMU-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Mus musculus 30616 R-MMU-216757 https://reactome.org/PathwayBrowser/#/R-MMU-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Mus musculus 30616 R-MMU-2168079 https://reactome.org/PathwayBrowser/#/R-MMU-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Mus musculus 30616 R-MMU-2176475 https://reactome.org/PathwayBrowser/#/R-MMU-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Mus musculus 30616 R-MMU-2197690 https://reactome.org/PathwayBrowser/#/R-MMU-2197690 Detachment of WASP/WAVE IEA Mus musculus 30616 R-MMU-2197698 https://reactome.org/PathwayBrowser/#/R-MMU-2197698 Src phosphorylate WASP,N-WASP IEA Mus musculus 30616 R-MMU-2213248 https://reactome.org/PathwayBrowser/#/R-MMU-2213248 Transport of antigen loaded MHC II molecules to surface IEA Mus musculus 30616 R-MMU-2214351 https://reactome.org/PathwayBrowser/#/R-MMU-2214351 PLK1 phosphorylates GORASP1 IEA Mus musculus 30616 R-MMU-2267372 https://reactome.org/PathwayBrowser/#/R-MMU-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Mus musculus 30616 R-MMU-2294580 https://reactome.org/PathwayBrowser/#/R-MMU-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Mus musculus 30616 R-MMU-2294600 https://reactome.org/PathwayBrowser/#/R-MMU-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Mus musculus 30616 R-MMU-2316434 https://reactome.org/PathwayBrowser/#/R-MMU-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-2395412 https://reactome.org/PathwayBrowser/#/R-MMU-2395412 Phosphorylation of SYK IEA Mus musculus 30616 R-MMU-2395436 https://reactome.org/PathwayBrowser/#/R-MMU-2395436 Phosphorylation of DAP12 TAS Mus musculus 30616 R-MMU-2395801 https://reactome.org/PathwayBrowser/#/R-MMU-2395801 Phosphorylation of LAT by p-SYK IEA Mus musculus 30616 R-MMU-2396002 https://reactome.org/PathwayBrowser/#/R-MMU-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex IEA Mus musculus 30616 R-MMU-2396007 https://reactome.org/PathwayBrowser/#/R-MMU-2396007 IRF3 is phosphorylated by TBK1 IEA Mus musculus 30616 R-MMU-2396594 https://reactome.org/PathwayBrowser/#/R-MMU-2396594 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus 30616 R-MMU-2404193 https://reactome.org/PathwayBrowser/#/R-MMU-2404193 IGF1R phosphorylates SHC1 IEA Mus musculus 30616 R-MMU-2404199 https://reactome.org/PathwayBrowser/#/R-MMU-2404199 IGF1,2:IGF1R autophosphorylates IEA Mus musculus 30616 R-MMU-2408505 https://reactome.org/PathwayBrowser/#/R-MMU-2408505 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by Pstk TAS Mus musculus 30616 R-MMU-2408551 https://reactome.org/PathwayBrowser/#/R-MMU-2408551 SeMet is converted to AdoSeMet by MAT IEA Mus musculus 30616 R-MMU-2422927 https://reactome.org/PathwayBrowser/#/R-MMU-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Mus musculus 30616 R-MMU-2424480 https://reactome.org/PathwayBrowser/#/R-MMU-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-2424484 https://reactome.org/PathwayBrowser/#/R-MMU-2424484 Phosphorylation of BTK by p-SYK IEA Mus musculus 30616 R-MMU-2424486 https://reactome.org/PathwayBrowser/#/R-MMU-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Mus musculus 30616 R-MMU-2424487 https://reactome.org/PathwayBrowser/#/R-MMU-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Mus musculus 30616 R-MMU-2428926 https://reactome.org/PathwayBrowser/#/R-MMU-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Mus musculus 30616 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus 30616 R-MMU-2466068 https://reactome.org/PathwayBrowser/#/R-MMU-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Mus musculus 30616 R-MMU-2468287 https://reactome.org/PathwayBrowser/#/R-MMU-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Mus musculus 30616 R-MMU-2468293 https://reactome.org/PathwayBrowser/#/R-MMU-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Mus musculus 30616 R-MMU-2470487 https://reactome.org/PathwayBrowser/#/R-MMU-2470487 Acvr2a phosphorylates Acvr1c in response to Activin TAS Mus musculus 30616 R-MMU-2529020 https://reactome.org/PathwayBrowser/#/R-MMU-2529020 CK2 phosphorylates condensin I subunits IEA Mus musculus 30616 R-MMU-2562526 https://reactome.org/PathwayBrowser/#/R-MMU-2562526 PLK1 phosphorylates OPTN IEA Mus musculus 30616 R-MMU-2574840 https://reactome.org/PathwayBrowser/#/R-MMU-2574840 AJUBA facilitates AURKA autophosphorylation IEA Mus musculus 30616 R-MMU-2581474 https://reactome.org/PathwayBrowser/#/R-MMU-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Mus musculus 30616 R-MMU-2586548 https://reactome.org/PathwayBrowser/#/R-MMU-2586548 Jak2 Autophosphorylates in Response to Leptin TAS Mus musculus 30616 R-MMU-2586557 https://reactome.org/PathwayBrowser/#/R-MMU-2586557 Jak2 Phosphorylates Lepr TAS Mus musculus 30616 R-MMU-265682 https://reactome.org/PathwayBrowser/#/R-MMU-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Mus musculus 30616 R-MMU-265783 https://reactome.org/PathwayBrowser/#/R-MMU-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-266082 https://reactome.org/PathwayBrowser/#/R-MMU-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Mus musculus 30616 R-MMU-2671740 https://reactome.org/PathwayBrowser/#/R-MMU-2671740 Jak2 Phosphorylates Shp2 in Response to Leptin TAS Mus musculus 30616 R-MMU-2671830 https://reactome.org/PathwayBrowser/#/R-MMU-2671830 Jak2 Phosphorylates Irs1/2 in Response to Leptin TAS Mus musculus 30616 R-MMU-2671836 https://reactome.org/PathwayBrowser/#/R-MMU-2671836 Jak2 Phosphorylates Stat3 in Response to Leptin TAS Mus musculus 30616 R-MMU-2671843 https://reactome.org/PathwayBrowser/#/R-MMU-2671843 Jak2 Phosphorylates Stat5 in Response to Leptin TAS Mus musculus 30616 R-MMU-2682349 https://reactome.org/PathwayBrowser/#/R-MMU-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Mus musculus 30616 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus 30616 R-MMU-2730835 https://reactome.org/PathwayBrowser/#/R-MMU-2730835 Autophosphorylation of PKC-theta IEA Mus musculus 30616 R-MMU-2730841 https://reactome.org/PathwayBrowser/#/R-MMU-2730841 Phosphorylation and activation of VAV IEA Mus musculus 30616 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus 30616 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus 30616 R-MMU-2730856 https://reactome.org/PathwayBrowser/#/R-MMU-2730856 Autophosphorylation of PAK IEA Mus musculus 30616 R-MMU-2730858 https://reactome.org/PathwayBrowser/#/R-MMU-2730858 Autophosphorylation of BTK/ITK IEA Mus musculus 30616 R-MMU-2730862 https://reactome.org/PathwayBrowser/#/R-MMU-2730862 Autophosphorylation of LYN kinase IEA Mus musculus 30616 R-MMU-2730863 https://reactome.org/PathwayBrowser/#/R-MMU-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Mus musculus 30616 R-MMU-2730868 https://reactome.org/PathwayBrowser/#/R-MMU-2730868 Phosphorylation of MEK7 by MEKK1 IEA Mus musculus 30616 R-MMU-2730869 https://reactome.org/PathwayBrowser/#/R-MMU-2730869 Phosphorylation of Gab2 by Syk/Fyn TAS Mus musculus 30616 R-MMU-2730870 https://reactome.org/PathwayBrowser/#/R-MMU-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Mus musculus 30616 R-MMU-2730876 https://reactome.org/PathwayBrowser/#/R-MMU-2730876 Phosphorylation of IKK-beta by TAK1 IEA Mus musculus 30616 R-MMU-2730880 https://reactome.org/PathwayBrowser/#/R-MMU-2730880 Autophosphorylation and activation of Mekk1 TAS Mus musculus 30616 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus 30616 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus 30616 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus 30616 R-MMU-2730896 https://reactome.org/PathwayBrowser/#/R-MMU-2730896 Phosphorylation of MEK4 by MEKK1 IEA Mus musculus 30616 R-MMU-2730900 https://reactome.org/PathwayBrowser/#/R-MMU-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Mus musculus 30616 R-MMU-2730904 https://reactome.org/PathwayBrowser/#/R-MMU-2730904 Auto-ubiquitination of TRAF6 IEA Mus musculus 30616 R-MMU-2855020 https://reactome.org/PathwayBrowser/#/R-MMU-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Mus musculus 30616 R-MMU-2984220 https://reactome.org/PathwayBrowser/#/R-MMU-2984220 CDK1:CCNB phosphorylates NEK9 IEA Mus musculus 30616 R-MMU-2984226 https://reactome.org/PathwayBrowser/#/R-MMU-2984226 PLK1 phosphorylates NEK9 IEA Mus musculus 30616 R-MMU-2990833 https://reactome.org/PathwayBrowser/#/R-MMU-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Mus musculus 30616 R-MMU-2990882 https://reactome.org/PathwayBrowser/#/R-MMU-2990882 CDK1 phosphorylates NUP98 IEA Mus musculus 30616 R-MMU-2993447 https://reactome.org/PathwayBrowser/#/R-MMU-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Mus musculus 30616 R-MMU-2993799 https://reactome.org/PathwayBrowser/#/R-MMU-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Mus musculus 30616 R-MMU-2993802 https://reactome.org/PathwayBrowser/#/R-MMU-2993802 HLCS biotinylates PC:Mn2+ IEA Mus musculus 30616 R-MMU-2993814 https://reactome.org/PathwayBrowser/#/R-MMU-2993814 HLCS biotinylates ACACA:Mn2+ IEA Mus musculus 30616 R-MMU-2993898 https://reactome.org/PathwayBrowser/#/R-MMU-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Mus musculus 30616 R-MMU-3000310 https://reactome.org/PathwayBrowser/#/R-MMU-3000310 AURKA phosphorylates PLK1 IEA Mus musculus 30616 R-MMU-3000327 https://reactome.org/PathwayBrowser/#/R-MMU-3000327 PLK1 phosphorylates BORA IEA Mus musculus 30616 R-MMU-3095901 https://reactome.org/PathwayBrowser/#/R-MMU-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Mus musculus 30616 R-MMU-3132737 https://reactome.org/PathwayBrowser/#/R-MMU-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Mus musculus 30616 R-MMU-3159253 https://reactome.org/PathwayBrowser/#/R-MMU-3159253 MMAB adenosylates cob(I)alamin IEA Mus musculus 30616 R-MMU-3222006 https://reactome.org/PathwayBrowser/#/R-MMU-3222006 STK11 (LKB1) phosphorylates NUAK1 IEA Mus musculus 30616 R-MMU-3222020 https://reactome.org/PathwayBrowser/#/R-MMU-3222020 NUAK1 phosphorylates TP53 IEA Mus musculus 30616 R-MMU-3228469 https://reactome.org/PathwayBrowser/#/R-MMU-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Mus musculus 30616 R-MMU-3238999 https://reactome.org/PathwayBrowser/#/R-MMU-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Mus musculus 30616 R-MMU-3239014 https://reactome.org/PathwayBrowser/#/R-MMU-3239014 MAPKAPK5 phosphorylates TP53 IEA Mus musculus 30616 R-MMU-3239019 https://reactome.org/PathwayBrowser/#/R-MMU-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Mus musculus 30616 R-MMU-3249371 https://reactome.org/PathwayBrowser/#/R-MMU-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Mus musculus 30616 R-MMU-3249379 https://reactome.org/PathwayBrowser/#/R-MMU-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Mus musculus 30616 R-MMU-3249390 https://reactome.org/PathwayBrowser/#/R-MMU-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Mus musculus 30616 R-MMU-3371422 https://reactome.org/PathwayBrowser/#/R-MMU-3371422 ATP hydrolysis by HSP70 IEA Mus musculus 30616 R-MMU-3371435 https://reactome.org/PathwayBrowser/#/R-MMU-3371435 Constitutive phosphorylation by GSK3 IEA Mus musculus 30616 R-MMU-3371531 https://reactome.org/PathwayBrowser/#/R-MMU-3371531 Constitutive phosphorylation by pERK1/2 IEA Mus musculus 30616 R-MMU-3371590 https://reactome.org/PathwayBrowser/#/R-MMU-3371590 HSP70 binds to HSP40:nascent protein IEA Mus musculus 30616 R-MMU-349426 https://reactome.org/PathwayBrowser/#/R-MMU-349426 Phosphorylation of MDM4 by CHEK2 IEA Mus musculus 30616 R-MMU-349444 https://reactome.org/PathwayBrowser/#/R-MMU-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Mus musculus 30616 R-MMU-349455 https://reactome.org/PathwayBrowser/#/R-MMU-349455 Phosphorylation of MDM4 by ATM IEA Mus musculus 30616 R-MMU-354073 https://reactome.org/PathwayBrowser/#/R-MMU-354073 Autophosphorylation of PTK2 at Y397 IEA Mus musculus 30616 R-MMU-354124 https://reactome.org/PathwayBrowser/#/R-MMU-354124 Phosphorylation of pPTK2 by SRC IEA Mus musculus 30616 R-MMU-3697899 https://reactome.org/PathwayBrowser/#/R-MMU-3697899 Atp7a transfers Cu from Atox1 to Sod3 TAS Mus musculus 30616 R-MMU-372693 https://reactome.org/PathwayBrowser/#/R-MMU-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Mus musculus 30616 R-MMU-373747 https://reactome.org/PathwayBrowser/#/R-MMU-373747 Phosphorylation of nephrin by FYN IEA Mus musculus 30616 R-MMU-373750 https://reactome.org/PathwayBrowser/#/R-MMU-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Mus musculus 30616 R-MMU-374664 https://reactome.org/PathwayBrowser/#/R-MMU-374664 Phosphorylation and activation of Ezrin IEA Mus musculus 30616 R-MMU-374701 https://reactome.org/PathwayBrowser/#/R-MMU-374701 Phosphorylation of DCC by Fyn IEA Mus musculus 30616 R-MMU-375160 https://reactome.org/PathwayBrowser/#/R-MMU-375160 NCAM1 binds to ATP IEA Mus musculus 30616 R-MMU-3769394 https://reactome.org/PathwayBrowser/#/R-MMU-3769394 AKT phosphorylates CBY1 IEA Mus musculus 30616 R-MMU-377186 https://reactome.org/PathwayBrowser/#/R-MMU-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Mus musculus 30616 R-MMU-3772435 https://reactome.org/PathwayBrowser/#/R-MMU-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Mus musculus 30616 R-MMU-3772436 https://reactome.org/PathwayBrowser/#/R-MMU-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Mus musculus 30616 R-MMU-377640 https://reactome.org/PathwayBrowser/#/R-MMU-377640 Autophosphorylation of SRC IEA Mus musculus 30616 R-MMU-3788705 https://reactome.org/PathwayBrowser/#/R-MMU-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Mus musculus 30616 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 30616 R-MMU-380272 https://reactome.org/PathwayBrowser/#/R-MMU-380272 Plk1-mediated phosphorylation of Nlp IEA Mus musculus 30616 R-MMU-380278 https://reactome.org/PathwayBrowser/#/R-MMU-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Mus musculus 30616 R-MMU-380780 https://reactome.org/PathwayBrowser/#/R-MMU-380780 Activation of Src IEA Mus musculus 30616 R-MMU-380927 https://reactome.org/PathwayBrowser/#/R-MMU-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Mus musculus 30616 R-MMU-381091 https://reactome.org/PathwayBrowser/#/R-MMU-381091 IRE1 dimer autophosphorylates IEA Mus musculus 30616 R-MMU-381111 https://reactome.org/PathwayBrowser/#/R-MMU-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Mus musculus 30616 R-MMU-382553 https://reactome.org/PathwayBrowser/#/R-MMU-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Mus musculus 30616 R-MMU-382560 https://reactome.org/PathwayBrowser/#/R-MMU-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Mus musculus 30616 R-MMU-382575 https://reactome.org/PathwayBrowser/#/R-MMU-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Mus musculus 30616 R-MMU-383190 https://reactome.org/PathwayBrowser/#/R-MMU-383190 HCO3- transport through ion channel IEA Mus musculus 30616 R-MMU-3857329 https://reactome.org/PathwayBrowser/#/R-MMU-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Mus musculus 30616 R-MMU-388831 https://reactome.org/PathwayBrowser/#/R-MMU-388831 Phosphorylation of CD28 IEA Mus musculus 30616 R-MMU-388833 https://reactome.org/PathwayBrowser/#/R-MMU-388833 Phosphorylation of CTLA-4 IEA Mus musculus 30616 R-MMU-389083 https://reactome.org/PathwayBrowser/#/R-MMU-389083 Autophosphorylation of PDGF alpha receptors IEA Mus musculus 30616 R-MMU-389086 https://reactome.org/PathwayBrowser/#/R-MMU-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Mus musculus 30616 R-MMU-389158 https://reactome.org/PathwayBrowser/#/R-MMU-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-389354 https://reactome.org/PathwayBrowser/#/R-MMU-389354 Activation of Vav1 IEA Mus musculus 30616 R-MMU-389622 https://reactome.org/PathwayBrowser/#/R-MMU-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 30616 R-MMU-389632 https://reactome.org/PathwayBrowser/#/R-MMU-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 30616 R-MMU-389652 https://reactome.org/PathwayBrowser/#/R-MMU-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Mus musculus 30616 R-MMU-389756 https://reactome.org/PathwayBrowser/#/R-MMU-389756 AKT interacts and phosphorylates Cot IEA Mus musculus 30616 R-MMU-389762 https://reactome.org/PathwayBrowser/#/R-MMU-389762 Phosphorylation of PD-1 IEA Mus musculus 30616 R-MMU-390593 https://reactome.org/PathwayBrowser/#/R-MMU-390593 ATP Hydrolysis By Myosin IEA Mus musculus 30616 R-MMU-390598 https://reactome.org/PathwayBrowser/#/R-MMU-390598 Myosin Binds ATP IEA Mus musculus 30616 R-MMU-392300 https://reactome.org/PathwayBrowser/#/R-MMU-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-392530 https://reactome.org/PathwayBrowser/#/R-MMU-392530 p-S400-Cot phosphorylates NIK IEA Mus musculus 30616 R-MMU-392751 https://reactome.org/PathwayBrowser/#/R-MMU-392751 L1 linked to actin cytoskeleton by ankyrin IEA Mus musculus 30616 R-MMU-392752 https://reactome.org/PathwayBrowser/#/R-MMU-392752 Phosphorylation of L1 by CK-II IEA Mus musculus 30616 R-MMU-3928578 https://reactome.org/PathwayBrowser/#/R-MMU-3928578 EPH receptors autophosphorylate IEA Mus musculus 30616 R-MMU-3928595 https://reactome.org/PathwayBrowser/#/R-MMU-3928595 N-WASP binds ARP2/3 and G-actin IEA Mus musculus 30616 R-MMU-3928599 https://reactome.org/PathwayBrowser/#/R-MMU-3928599 Ptk2 autophosphorylates at Y397 TAS Mus musculus 30616 R-MMU-3928604 https://reactome.org/PathwayBrowser/#/R-MMU-3928604 SFKs phosphorylate VAV2,3 IEA Mus musculus 30616 R-MMU-3928613 https://reactome.org/PathwayBrowser/#/R-MMU-3928613 Fyn phosphorylates Nmdar2b TAS Mus musculus 30616 R-MMU-3928620 https://reactome.org/PathwayBrowser/#/R-MMU-3928620 PAK1 autophosphorylates IEA Mus musculus 30616 R-MMU-3928622 https://reactome.org/PathwayBrowser/#/R-MMU-3928622 SFKs phosphorylate Git1 TAS Mus musculus 30616 R-MMU-3928625 https://reactome.org/PathwayBrowser/#/R-MMU-3928625 PAKs autophosphorylate IEA Mus musculus 30616 R-MMU-3928627 https://reactome.org/PathwayBrowser/#/R-MMU-3928627 EPHB phosphorylates TIAM1 IEA Mus musculus 30616 R-MMU-399939 https://reactome.org/PathwayBrowser/#/R-MMU-399939 Autophosphorylation of PAK IEA Mus musculus 30616 R-MMU-399944 https://reactome.org/PathwayBrowser/#/R-MMU-399944 Phosphorylation of CRMPs by Cdk5 IEA Mus musculus 30616 R-MMU-399947 https://reactome.org/PathwayBrowser/#/R-MMU-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Mus musculus 30616 R-MMU-399951 https://reactome.org/PathwayBrowser/#/R-MMU-399951 Phosphorylation of CRMPs by GSK3beta IEA Mus musculus 30616 R-MMU-399952 https://reactome.org/PathwayBrowser/#/R-MMU-399952 Phosphorylation of LIMK-1 by PAK IEA Mus musculus 30616 R-MMU-399978 https://reactome.org/PathwayBrowser/#/R-MMU-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Mus musculus 30616 R-MMU-4085028 https://reactome.org/PathwayBrowser/#/R-MMU-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Mus musculus 30616 R-MMU-4086410 https://reactome.org/PathwayBrowser/#/R-MMU-4086410 CDK1 phosphorylates BORA IEA Mus musculus 30616 R-MMU-4088024 https://reactome.org/PathwayBrowser/#/R-MMU-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Mus musculus 30616 R-MMU-4088134 https://reactome.org/PathwayBrowser/#/R-MMU-4088134 PLK1 phosphorylates FOXM1 IEA Mus musculus 30616 R-MMU-4093332 https://reactome.org/PathwayBrowser/#/R-MMU-4093332 p-EPHB phosphorylates SDC2 IEA Mus musculus 30616 R-MMU-416320 https://reactome.org/PathwayBrowser/#/R-MMU-416320 Trafficking of GluR1-containing AMPA receptors IEA Mus musculus 30616 R-MMU-416639 https://reactome.org/PathwayBrowser/#/R-MMU-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Mus musculus 30616 R-MMU-4167511 https://reactome.org/PathwayBrowser/#/R-MMU-4167511 HLCS biotinylates ACACB IEA Mus musculus 30616 R-MMU-416985 https://reactome.org/PathwayBrowser/#/R-MMU-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Mus musculus 30616 R-MMU-417927 https://reactome.org/PathwayBrowser/#/R-MMU-417927 P2Y2 receptor binds ATP and UTP IEA Mus musculus 30616 R-MMU-418845 https://reactome.org/PathwayBrowser/#/R-MMU-418845 Activation of caspase-3 IEA Mus musculus 30616 R-MMU-418870 https://reactome.org/PathwayBrowser/#/R-MMU-418870 Phosphorylation of Unc5C TAS Mus musculus 30616 R-MMU-419490 https://reactome.org/PathwayBrowser/#/R-MMU-419490 Binding of ATP to P2X receptors IEA Mus musculus 30616 R-MMU-419644 https://reactome.org/PathwayBrowser/#/R-MMU-419644 Transphosphorylation of pLIMK1 IEA Mus musculus 30616 R-MMU-419646 https://reactome.org/PathwayBrowser/#/R-MMU-419646 SEMA4D interacts with Plexin-B1:Met IEA Mus musculus 30616 R-MMU-420382 https://reactome.org/PathwayBrowser/#/R-MMU-420382 Phosphorylation of FAK by Src kinases TAS Mus musculus 30616 R-MMU-420394 https://reactome.org/PathwayBrowser/#/R-MMU-420394 Recruitment of FAK to NCAM1:Fyn in lipid rafts TAS Mus musculus 30616 R-MMU-421007 https://reactome.org/PathwayBrowser/#/R-MMU-421007 Endocytosis of Ca impermeable AMPA receptors IEA Mus musculus 30616 R-MMU-421143 https://reactome.org/PathwayBrowser/#/R-MMU-421143 Phosphorylation of Plexin-A TAS Mus musculus 30616 R-MMU-421694 https://reactome.org/PathwayBrowser/#/R-MMU-421694 Phosphorylation of FADK1 TAS Mus musculus 30616 R-MMU-421836 https://reactome.org/PathwayBrowser/#/R-MMU-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Mus musculus 30616 R-MMU-426240 https://reactome.org/PathwayBrowser/#/R-MMU-426240 DAG kinase produces phosphatidic acid from DAG IEA Mus musculus 30616 R-MMU-428273 https://reactome.org/PathwayBrowser/#/R-MMU-428273 SPHK1 phosphorylates sphingoid IEA Mus musculus 30616 R-MMU-428888 https://reactome.org/PathwayBrowser/#/R-MMU-428888 Phosphorylation of ROBO1 by ABL kinase IEA Mus musculus 30616 R-MMU-428941 https://reactome.org/PathwayBrowser/#/R-MMU-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Mus musculus 30616 R-MMU-428961 https://reactome.org/PathwayBrowser/#/R-MMU-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Mus musculus 30616 R-MMU-429016 https://reactome.org/PathwayBrowser/#/R-MMU-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Mus musculus 30616 R-MMU-429157 https://reactome.org/PathwayBrowser/#/R-MMU-429157 ABCC4 accumulation of dense granule contents IEA Mus musculus 30616 R-MMU-429441 https://reactome.org/PathwayBrowser/#/R-MMU-429441 SYK activation by SRC IEA Mus musculus 30616 R-MMU-429449 https://reactome.org/PathwayBrowser/#/R-MMU-429449 Syk activation leads to SLP-76 activation IEA Mus musculus 30616 R-MMU-430347 https://reactome.org/PathwayBrowser/#/R-MMU-430347 MigFilin associates with Filamin and F-actin IEA Mus musculus 30616 R-MMU-432129 https://reactome.org/PathwayBrowser/#/R-MMU-432129 FGR binds and phosphorylates LRP8 IEA Mus musculus 30616 R-MMU-432148 https://reactome.org/PathwayBrowser/#/R-MMU-432148 Fgr may phosphorylate p38 MAPK IEA Mus musculus 30616 R-MMU-432232 https://reactome.org/PathwayBrowser/#/R-MMU-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Mus musculus 30616 R-MMU-432688 https://reactome.org/PathwayBrowser/#/R-MMU-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating IEA Mus musculus 30616 R-MMU-4332358 https://reactome.org/PathwayBrowser/#/R-MMU-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Mus musculus 30616 R-MMU-4332363 https://reactome.org/PathwayBrowser/#/R-MMU-4332363 Autophosphorylation and activation of CAMK2 IEA Mus musculus 30616 R-MMU-434382 https://reactome.org/PathwayBrowser/#/R-MMU-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Mus musculus 30616 R-MMU-434836 https://reactome.org/PathwayBrowser/#/R-MMU-434836 Syk/Lck phosphorylate LAT IEA Mus musculus 30616 R-MMU-435244 https://reactome.org/PathwayBrowser/#/R-MMU-435244 PECAM1 is phosphorylated IEA Mus musculus 30616 R-MMU-437162 https://reactome.org/PathwayBrowser/#/R-MMU-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-4411383 https://reactome.org/PathwayBrowser/#/R-MMU-4411383 NLK phosphorylates TCF/LEF IEA Mus musculus 30616 R-MMU-4411402 https://reactome.org/PathwayBrowser/#/R-MMU-4411402 Activation of NLK IEA Mus musculus 30616 R-MMU-4420117 https://reactome.org/PathwayBrowser/#/R-MMU-4420117 VEGFR2 autophosphorylates IEA Mus musculus 30616 R-MMU-4420121 https://reactome.org/PathwayBrowser/#/R-MMU-4420121 SFKs phosphorylate PLCG1 IEA Mus musculus 30616 R-MMU-4420128 https://reactome.org/PathwayBrowser/#/R-MMU-4420128 SRC-1 phosphorylates SHB IEA Mus musculus 30616 R-MMU-4420206 https://reactome.org/PathwayBrowser/#/R-MMU-4420206 Phosphorylation of SRC-1 IEA Mus musculus 30616 R-MMU-442724 https://reactome.org/PathwayBrowser/#/R-MMU-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Mus musculus 30616 R-MMU-442749 https://reactome.org/PathwayBrowser/#/R-MMU-442749 CaMKK autophosphorylates in the nucleus IEA Mus musculus 30616 R-MMU-443779 https://reactome.org/PathwayBrowser/#/R-MMU-443779 Linkage of L1 with treadmilling F-actin IEA Mus musculus 30616 R-MMU-445072 https://reactome.org/PathwayBrowser/#/R-MMU-445072 Interaction of PAK1 with Rac1-GTP IEA Mus musculus 30616 R-MMU-445079 https://reactome.org/PathwayBrowser/#/R-MMU-445079 Phosphorylation of L1 by ERK IEA Mus musculus 30616 R-MMU-445084 https://reactome.org/PathwayBrowser/#/R-MMU-445084 Phosphorylation of L1 by SRC IEA Mus musculus 30616 R-MMU-445699 https://reactome.org/PathwayBrowser/#/R-MMU-445699 ATP Hydrolysis By Myosin IEA Mus musculus 30616 R-MMU-445700 https://reactome.org/PathwayBrowser/#/R-MMU-445700 Myosin Binds ATP IEA Mus musculus 30616 R-MMU-445813 https://reactome.org/PathwayBrowser/#/R-MMU-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Mus musculus 30616 R-MMU-446634 https://reactome.org/PathwayBrowser/#/R-MMU-446634 IRAK4 is activated by autophosphorylation IEA Mus musculus 30616 R-MMU-446694 https://reactome.org/PathwayBrowser/#/R-MMU-446694 IRAK4 phosphorylates IRAK1 IEA Mus musculus 30616 R-MMU-446701 https://reactome.org/PathwayBrowser/#/R-MMU-446701 IRAK4-activated IRAK1 autophosphorylates IEA Mus musculus 30616 R-MMU-447074 https://reactome.org/PathwayBrowser/#/R-MMU-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Mus musculus 30616 R-MMU-448953 https://reactome.org/PathwayBrowser/#/R-MMU-448953 Phosphorylation of E47 by p38 MAPK TAS Mus musculus 30616 R-MMU-448955 https://reactome.org/PathwayBrowser/#/R-MMU-448955 Phosphorylation of MEF2 proteins by p38 IEA Mus musculus 30616 R-MMU-448961 https://reactome.org/PathwayBrowser/#/R-MMU-448961 Activation of p38 alpha/beta MAPK TAS Mus musculus 30616 R-MMU-449911 https://reactome.org/PathwayBrowser/#/R-MMU-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Mus musculus 30616 R-MMU-450088 https://reactome.org/PathwayBrowser/#/R-MMU-450088 GLUT1 tetramer binds 4xATP IEA Mus musculus 30616 R-MMU-450092 https://reactome.org/PathwayBrowser/#/R-MMU-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Mus musculus 30616 R-MMU-450222 https://reactome.org/PathwayBrowser/#/R-MMU-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Mus musculus 30616 R-MMU-450325 https://reactome.org/PathwayBrowser/#/R-MMU-450325 c-FOS activation by phospho ERK1/2 IEA Mus musculus 30616 R-MMU-450333 https://reactome.org/PathwayBrowser/#/R-MMU-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Mus musculus 30616 R-MMU-450337 https://reactome.org/PathwayBrowser/#/R-MMU-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Mus musculus 30616 R-MMU-450346 https://reactome.org/PathwayBrowser/#/R-MMU-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Mus musculus 30616 R-MMU-450463 https://reactome.org/PathwayBrowser/#/R-MMU-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Mus musculus 30616 R-MMU-450474 https://reactome.org/PathwayBrowser/#/R-MMU-450474 MK2 phosphorylates BRF1 IEA Mus musculus 30616 R-MMU-450490 https://reactome.org/PathwayBrowser/#/R-MMU-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Mus musculus 30616 R-MMU-450499 https://reactome.org/PathwayBrowser/#/R-MMU-450499 Protein Kinase B (AKT) phosphorylates KSRP IEA Mus musculus 30616 R-MMU-450533 https://reactome.org/PathwayBrowser/#/R-MMU-450533 PKCdelta phosphorylates HuR IEA Mus musculus 30616 R-MMU-450550 https://reactome.org/PathwayBrowser/#/R-MMU-450550 PKCalpha phosphorylates HuR IEA Mus musculus 30616 R-MMU-450827 https://reactome.org/PathwayBrowser/#/R-MMU-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Mus musculus 30616 R-MMU-451204 https://reactome.org/PathwayBrowser/#/R-MMU-451204 Phosphorylation of Khsrp by p38 TAS Mus musculus 30616 R-MMU-451942 https://reactome.org/PathwayBrowser/#/R-MMU-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Mus musculus 30616 R-MMU-452097 https://reactome.org/PathwayBrowser/#/R-MMU-452097 Recruited STAT5 is phosphorylated IEA Mus musculus 30616 R-MMU-452100 https://reactome.org/PathwayBrowser/#/R-MMU-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Mus musculus 30616 R-MMU-452122 https://reactome.org/PathwayBrowser/#/R-MMU-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Mus musculus 30616 R-MMU-453200 https://reactome.org/PathwayBrowser/#/R-MMU-453200 SYK autophosphorylates IEA Mus musculus 30616 R-MMU-453342 https://reactome.org/PathwayBrowser/#/R-MMU-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Mus musculus 30616 R-MMU-4551572 https://reactome.org/PathwayBrowser/#/R-MMU-4551572 Vangl2 is phosphorylated in response to Wnt5a TAS Mus musculus 30616 R-MMU-4793911 https://reactome.org/PathwayBrowser/#/R-MMU-4793911 MAPKAPK2 phosphorylates HSF1 IEA Mus musculus 30616 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 30616 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 30616 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 30616 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 30616 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 30616 R-MMU-504054 https://reactome.org/PathwayBrowser/#/R-MMU-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Mus musculus 30616 R-MMU-508040 https://reactome.org/PathwayBrowser/#/R-MMU-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Mus musculus 30616 R-MMU-5082387 https://reactome.org/PathwayBrowser/#/R-MMU-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Mus musculus 30616 R-MMU-5082405 https://reactome.org/PathwayBrowser/#/R-MMU-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Mus musculus 30616 R-MMU-508282 https://reactome.org/PathwayBrowser/#/R-MMU-508282 SYK is a substrate for JAK1 IEA Mus musculus 30616 R-MMU-508308 https://reactome.org/PathwayBrowser/#/R-MMU-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Mus musculus 30616 R-MMU-5138432 https://reactome.org/PathwayBrowser/#/R-MMU-5138432 DVL2 is phosphorylated by PKC IEA Mus musculus 30616 R-MMU-5195402 https://reactome.org/PathwayBrowser/#/R-MMU-5195402 CDK1 phosphorylates LPIN IEA Mus musculus 30616 R-MMU-5213464 https://reactome.org/PathwayBrowser/#/R-MMU-5213464 RIPK1 is phosphorylated IEA Mus musculus 30616 R-MMU-5213466 https://reactome.org/PathwayBrowser/#/R-MMU-5213466 RIPK3 is phosphorylated IEA Mus musculus 30616 R-MMU-5218640 https://reactome.org/PathwayBrowser/#/R-MMU-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Mus musculus 30616 R-MMU-5218642 https://reactome.org/PathwayBrowser/#/R-MMU-5218642 PTK2 autophosphorylates IEA Mus musculus 30616 R-MMU-5218804 https://reactome.org/PathwayBrowser/#/R-MMU-5218804 p38 MAPK activation by VEGFR IEA Mus musculus 30616 R-MMU-5218805 https://reactome.org/PathwayBrowser/#/R-MMU-5218805 PKC autophosphorylates IEA Mus musculus 30616 R-MMU-5218806 https://reactome.org/PathwayBrowser/#/R-MMU-5218806 FYN autophosphorylates IEA Mus musculus 30616 R-MMU-5218809 https://reactome.org/PathwayBrowser/#/R-MMU-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Mus musculus 30616 R-MMU-5218812 https://reactome.org/PathwayBrowser/#/R-MMU-5218812 FYN phosphorylates PAK2 IEA Mus musculus 30616 R-MMU-5218814 https://reactome.org/PathwayBrowser/#/R-MMU-5218814 PAK2 autophorylates IEA Mus musculus 30616 R-MMU-5218819 https://reactome.org/PathwayBrowser/#/R-MMU-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-5218820 https://reactome.org/PathwayBrowser/#/R-MMU-5218820 Src kinases phosphorylate VAV IEA Mus musculus 30616 R-MMU-5218821 https://reactome.org/PathwayBrowser/#/R-MMU-5218821 PDK1 phosphorylates PKC IEA Mus musculus 30616 R-MMU-5218823 https://reactome.org/PathwayBrowser/#/R-MMU-5218823 PKC phosphorylates sphingosine kinase 1 IEA Mus musculus 30616 R-MMU-5218826 https://reactome.org/PathwayBrowser/#/R-MMU-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Mus musculus 30616 R-MMU-5218830 https://reactome.org/PathwayBrowser/#/R-MMU-5218830 SRC-1 phosphorylates PTK2-beta IEA Mus musculus 30616 R-MMU-5218834 https://reactome.org/PathwayBrowser/#/R-MMU-5218834 Fak/Src phosphorylate p130Cas TAS Mus musculus 30616 R-MMU-5218845 https://reactome.org/PathwayBrowser/#/R-MMU-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Mus musculus 30616 R-MMU-5218851 https://reactome.org/PathwayBrowser/#/R-MMU-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Mus musculus 30616 R-MMU-5218854 https://reactome.org/PathwayBrowser/#/R-MMU-5218854 p-Y420-FYN is phosphorylated on S21 IEA Mus musculus 30616 R-MMU-5218906 https://reactome.org/PathwayBrowser/#/R-MMU-5218906 RIPK3 phosphorylates MLKL IEA Mus musculus 30616 R-MMU-5218916 https://reactome.org/PathwayBrowser/#/R-MMU-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Mus musculus 30616 R-MMU-5223313 https://reactome.org/PathwayBrowser/#/R-MMU-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Mus musculus 30616 R-MMU-5223317 https://reactome.org/PathwayBrowser/#/R-MMU-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Mus musculus 30616 R-MMU-5229194 https://reactome.org/PathwayBrowser/#/R-MMU-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Mus musculus 30616 R-MMU-5229343 https://reactome.org/PathwayBrowser/#/R-MMU-5229343 AXIN is phosphorylated in the destruction complex IEA Mus musculus 30616 R-MMU-5244669 https://reactome.org/PathwayBrowser/#/R-MMU-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Mus musculus 30616 R-MMU-5251942 https://reactome.org/PathwayBrowser/#/R-MMU-5251942 Hikeshi binds HSP70s:ATP IEA Mus musculus 30616 R-MMU-5251955 https://reactome.org/PathwayBrowser/#/R-MMU-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Mus musculus 30616 R-MMU-5251959 https://reactome.org/PathwayBrowser/#/R-MMU-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Mus musculus 30616 R-MMU-5251989 https://reactome.org/PathwayBrowser/#/R-MMU-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Mus musculus 30616 R-MMU-5252041 https://reactome.org/PathwayBrowser/#/R-MMU-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Mus musculus 30616 R-MMU-5252079 https://reactome.org/PathwayBrowser/#/R-MMU-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Mus musculus 30616 R-MMU-5263624 https://reactome.org/PathwayBrowser/#/R-MMU-5263624 p-Akt2 phosphorylates C2cd5 TAS Mus musculus 30616 R-MMU-5339524 https://reactome.org/PathwayBrowser/#/R-MMU-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Mus musculus 30616 R-MMU-5357429 https://reactome.org/PathwayBrowser/#/R-MMU-5357429 AXL autophosphorylates on Y779 and Y821 IEA Mus musculus 30616 R-MMU-5357472 https://reactome.org/PathwayBrowser/#/R-MMU-5357472 PAK1-3 autophosphorylates IEA Mus musculus 30616 R-MMU-5357477 https://reactome.org/PathwayBrowser/#/R-MMU-5357477 PAK1-3 phosphorylates VE-cadherin IEA Mus musculus 30616 R-MMU-5357831 https://reactome.org/PathwayBrowser/#/R-MMU-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Mus musculus 30616 R-MMU-5358475 https://reactome.org/PathwayBrowser/#/R-MMU-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Mus musculus 30616 R-MMU-5358510 https://reactome.org/PathwayBrowser/#/R-MMU-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Mus musculus 30616 R-MMU-5358518 https://reactome.org/PathwayBrowser/#/R-MMU-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Mus musculus 30616 R-MMU-5358592 https://reactome.org/PathwayBrowser/#/R-MMU-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Mus musculus 30616 R-MMU-5358597 https://reactome.org/PathwayBrowser/#/R-MMU-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Mus musculus 30616 R-MMU-5358599 https://reactome.org/PathwayBrowser/#/R-MMU-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Mus musculus 30616 R-MMU-5358912 https://reactome.org/PathwayBrowser/#/R-MMU-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Mus musculus 30616 R-MMU-5362459 https://reactome.org/PathwayBrowser/#/R-MMU-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Mus musculus 30616 R-MMU-548843 https://reactome.org/PathwayBrowser/#/R-MMU-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Mus musculus 30616 R-MMU-548973 https://reactome.org/PathwayBrowser/#/R-MMU-548973 Phosphorylation of ITIM in SIRP alpha TAS Mus musculus 30616 R-MMU-5578777 https://reactome.org/PathwayBrowser/#/R-MMU-5578777 DMPK phosphorylates PLN IEA Mus musculus 30616 R-MMU-5603114 https://reactome.org/PathwayBrowser/#/R-MMU-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Mus musculus 30616 R-MMU-5607722 https://reactome.org/PathwayBrowser/#/R-MMU-5607722 Active NIK phosphorylates IKKA dimer IEA Mus musculus 30616 R-MMU-5607726 https://reactome.org/PathwayBrowser/#/R-MMU-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Mus musculus 30616 R-MMU-5607732 https://reactome.org/PathwayBrowser/#/R-MMU-5607732 K63polyUb-TAK1 autophosphorylates IEA Mus musculus 30616 R-MMU-5607740 https://reactome.org/PathwayBrowser/#/R-MMU-5607740 PKC-delta phosphorylates CARD9 IEA Mus musculus 30616 R-MMU-5607742 https://reactome.org/PathwayBrowser/#/R-MMU-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Mus musculus 30616 R-MMU-5607750 https://reactome.org/PathwayBrowser/#/R-MMU-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Mus musculus 30616 R-MMU-5607754 https://reactome.org/PathwayBrowser/#/R-MMU-5607754 1,3-beta-D-glucan:p-15Y-Clec7a:Syk phosphorylates Plcg2 TAS Mus musculus 30616 R-MMU-5607756 https://reactome.org/PathwayBrowser/#/R-MMU-5607756 TRAF6 oligomer autoubiquitinates IEA Mus musculus 30616 R-MMU-5607757 https://reactome.org/PathwayBrowser/#/R-MMU-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 IEA Mus musculus 30616 R-MMU-5610710 https://reactome.org/PathwayBrowser/#/R-MMU-5610710 Pka phosphorylates Gli2 TAS Mus musculus 30616 R-MMU-5610720 https://reactome.org/PathwayBrowser/#/R-MMU-5610720 PKA phosphorylates GLI3 IEA Mus musculus 30616 R-MMU-5610722 https://reactome.org/PathwayBrowser/#/R-MMU-5610722 CK1 phosphorylates p-GLI3 IEA Mus musculus 30616 R-MMU-5610727 https://reactome.org/PathwayBrowser/#/R-MMU-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Mus musculus 30616 R-MMU-5610732 https://reactome.org/PathwayBrowser/#/R-MMU-5610732 GSK3 phosphorylates p-GLI3 IEA Mus musculus 30616 R-MMU-5617179 https://reactome.org/PathwayBrowser/#/R-MMU-5617179 PRKACA phosphorylates TNNI3 IEA Mus musculus 30616 R-MMU-5617182 https://reactome.org/PathwayBrowser/#/R-MMU-5617182 PRKACA phosphorylates PLN IEA Mus musculus 30616 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 30616 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 30616 R-MMU-5618085 https://reactome.org/PathwayBrowser/#/R-MMU-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Mus musculus 30616 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 30616 R-MMU-5618098 https://reactome.org/PathwayBrowser/#/R-MMU-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Mus musculus 30616 R-MMU-5618099 https://reactome.org/PathwayBrowser/#/R-MMU-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Mus musculus 30616 R-MMU-5618105 https://reactome.org/PathwayBrowser/#/R-MMU-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Mus musculus 30616 R-MMU-5618107 https://reactome.org/PathwayBrowser/#/R-MMU-5618107 ATP binding to HSP90 triggers conformation change IEA Mus musculus 30616 R-MMU-5618110 https://reactome.org/PathwayBrowser/#/R-MMU-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Mus musculus 30616 R-MMU-5621355 https://reactome.org/PathwayBrowser/#/R-MMU-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Mus musculus 30616 R-MMU-5621363 https://reactome.org/PathwayBrowser/#/R-MMU-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Mus musculus 30616 R-MMU-5621370 https://reactome.org/PathwayBrowser/#/R-MMU-5621370 SYK autophosphorylates IEA Mus musculus 30616 R-MMU-5623667 https://reactome.org/PathwayBrowser/#/R-MMU-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Mus musculus 30616 R-MMU-5624473 https://reactome.org/PathwayBrowser/#/R-MMU-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Mus musculus 30616 R-MMU-5624486 https://reactome.org/PathwayBrowser/#/R-MMU-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Mus musculus 30616 R-MMU-5624492 https://reactome.org/PathwayBrowser/#/R-MMU-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Mus musculus 30616 R-MMU-5626507 https://reactome.org/PathwayBrowser/#/R-MMU-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Mus musculus 30616 R-MMU-5627775 https://reactome.org/PathwayBrowser/#/R-MMU-5627775 Autophosphorylation of PAK1,2,3 IEA Mus musculus 30616 R-MMU-5632661 https://reactome.org/PathwayBrowser/#/R-MMU-5632661 Csnk1a1 phosphorylates Smo dimer TAS Mus musculus 30616 R-MMU-5632665 https://reactome.org/PathwayBrowser/#/R-MMU-5632665 Adrbk1 phosphorylates Smo dimer TAS Mus musculus 30616 R-MMU-5635842 https://reactome.org/PathwayBrowser/#/R-MMU-5635842 ULK3 phosphorylates GLI IEA Mus musculus 30616 R-MMU-5654147 https://reactome.org/PathwayBrowser/#/R-MMU-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Mus musculus 30616 R-MMU-5654149 https://reactome.org/PathwayBrowser/#/R-MMU-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Mus musculus 30616 R-MMU-5654151 https://reactome.org/PathwayBrowser/#/R-MMU-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Mus musculus 30616 R-MMU-5654222 https://reactome.org/PathwayBrowser/#/R-MMU-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Mus musculus 30616 R-MMU-5654397 https://reactome.org/PathwayBrowser/#/R-MMU-5654397 Activated FGFR2 phosphorylates FRS2 IEA Mus musculus 30616 R-MMU-5654407 https://reactome.org/PathwayBrowser/#/R-MMU-5654407 Activated FGFR2 phosphorylates SHC1 IEA Mus musculus 30616 R-MMU-5654408 https://reactome.org/PathwayBrowser/#/R-MMU-5654408 Activated FGFR3 phosphorylates FRS2 IEA Mus musculus 30616 R-MMU-5654418 https://reactome.org/PathwayBrowser/#/R-MMU-5654418 Activated FGFR4 phosphorylates FRS2 IEA Mus musculus 30616 R-MMU-5654428 https://reactome.org/PathwayBrowser/#/R-MMU-5654428 Activated FGFR4 phosphorylates SHC1 IEA Mus musculus 30616 R-MMU-5654560 https://reactome.org/PathwayBrowser/#/R-MMU-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Mus musculus 30616 R-MMU-5654562 https://reactome.org/PathwayBrowser/#/R-MMU-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Mus musculus 30616 R-MMU-5654565 https://reactome.org/PathwayBrowser/#/R-MMU-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Mus musculus 30616 R-MMU-5654566 https://reactome.org/PathwayBrowser/#/R-MMU-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Mus musculus 30616 R-MMU-5654575 https://reactome.org/PathwayBrowser/#/R-MMU-5654575 Activated FGFR1 phosphorylates FRS2 IEA Mus musculus 30616 R-MMU-5654578 https://reactome.org/PathwayBrowser/#/R-MMU-5654578 Activated FGFR1 phosphorylates FRS3 IEA Mus musculus 30616 R-MMU-5654582 https://reactome.org/PathwayBrowser/#/R-MMU-5654582 Activated FGFR1 phosphorylates SHC1 IEA Mus musculus 30616 R-MMU-5654587 https://reactome.org/PathwayBrowser/#/R-MMU-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Mus musculus 30616 R-MMU-5654605 https://reactome.org/PathwayBrowser/#/R-MMU-5654605 Activated FGFR2 phosphorylates FRS3 IEA Mus musculus 30616 R-MMU-5654607 https://reactome.org/PathwayBrowser/#/R-MMU-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Mus musculus 30616 R-MMU-5654628 https://reactome.org/PathwayBrowser/#/R-MMU-5654628 Activated FGFR3 phosphorylates FRS3 IEA Mus musculus 30616 R-MMU-5654631 https://reactome.org/PathwayBrowser/#/R-MMU-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Mus musculus 30616 R-MMU-5654634 https://reactome.org/PathwayBrowser/#/R-MMU-5654634 Activated FGFR3 phosphorylates SHC1 IEA Mus musculus 30616 R-MMU-5654653 https://reactome.org/PathwayBrowser/#/R-MMU-5654653 Activated FGFR4 phosphorylates FRS3 IEA Mus musculus 30616 R-MMU-5654655 https://reactome.org/PathwayBrowser/#/R-MMU-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Mus musculus 30616 R-MMU-5654690 https://reactome.org/PathwayBrowser/#/R-MMU-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-5654692 https://reactome.org/PathwayBrowser/#/R-MMU-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-5654697 https://reactome.org/PathwayBrowser/#/R-MMU-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-5654701 https://reactome.org/PathwayBrowser/#/R-MMU-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-5654705 https://reactome.org/PathwayBrowser/#/R-MMU-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-5654709 https://reactome.org/PathwayBrowser/#/R-MMU-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-5654714 https://reactome.org/PathwayBrowser/#/R-MMU-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-5654717 https://reactome.org/PathwayBrowser/#/R-MMU-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-5654989 https://reactome.org/PathwayBrowser/#/R-MMU-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Mus musculus 30616 R-MMU-5662466 https://reactome.org/PathwayBrowser/#/R-MMU-5662466 XYLB phosphorylates D-xylulose IEA Mus musculus 30616 R-MMU-5665751 https://reactome.org/PathwayBrowser/#/R-MMU-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin IEA Mus musculus 30616 R-MMU-5665767 https://reactome.org/PathwayBrowser/#/R-MMU-5665767 Activated FMNL3 binds G-actin IEA Mus musculus 30616 R-MMU-5665802 https://reactome.org/PathwayBrowser/#/R-MMU-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Mus musculus 30616 R-MMU-5665809 https://reactome.org/PathwayBrowser/#/R-MMU-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Mus musculus 30616 R-MMU-5665868 https://reactome.org/PathwayBrowser/#/R-MMU-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Mus musculus 30616 R-MMU-5665982 https://reactome.org/PathwayBrowser/#/R-MMU-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 IEA Mus musculus 30616 R-MMU-5666001 https://reactome.org/PathwayBrowser/#/R-MMU-5666001 Profilin:G-actin binds MKL1 IEA Mus musculus 30616 R-MMU-5666160 https://reactome.org/PathwayBrowser/#/R-MMU-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Mus musculus 30616 R-MMU-5668545 https://reactome.org/PathwayBrowser/#/R-MMU-5668545 NIK autophosphorylates on T559 IEA Mus musculus 30616 R-MMU-5668932 https://reactome.org/PathwayBrowser/#/R-MMU-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Mus musculus 30616 R-MMU-5668947 https://reactome.org/PathwayBrowser/#/R-MMU-5668947 PAK1 phosphorylates myosin phosphatase IEA Mus musculus 30616 R-MMU-5668984 https://reactome.org/PathwayBrowser/#/R-MMU-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Mus musculus 30616 R-MMU-5669250 https://reactome.org/PathwayBrowser/#/R-MMU-5669250 PAK1 phosphorylates FLNA IEA Mus musculus 30616 R-MMU-5671749 https://reactome.org/PathwayBrowser/#/R-MMU-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Mus musculus 30616 R-MMU-5671763 https://reactome.org/PathwayBrowser/#/R-MMU-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Mus musculus 30616 R-MMU-5672008 https://reactome.org/PathwayBrowser/#/R-MMU-5672008 Thr-180 of ULK1 is phosphorylated IEA Mus musculus 30616 R-MMU-5672010 https://reactome.org/PathwayBrowser/#/R-MMU-5672010 Active MTORC1 phosphorylates ULK1 IEA Mus musculus 30616 R-MMU-5672012 https://reactome.org/PathwayBrowser/#/R-MMU-5672012 Beclin-1 complex phosphorylates PtdIns IEA Mus musculus 30616 R-MMU-5672027 https://reactome.org/PathwayBrowser/#/R-MMU-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Mus musculus 30616 R-MMU-5672828 https://reactome.org/PathwayBrowser/#/R-MMU-5672828 mTORC1 phosphorylates AKT1S1 IEA Mus musculus 30616 R-MMU-5672948 https://reactome.org/PathwayBrowser/#/R-MMU-5672948 MARK3 phosphorylates KSR1 IEA Mus musculus 30616 R-MMU-5672969 https://reactome.org/PathwayBrowser/#/R-MMU-5672969 Phosphorylation of RAF IEA Mus musculus 30616 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 30616 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 30616 R-MMU-5673768 https://reactome.org/PathwayBrowser/#/R-MMU-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Mus musculus 30616 R-MMU-5674130 https://reactome.org/PathwayBrowser/#/R-MMU-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Mus musculus 30616 R-MMU-5674373 https://reactome.org/PathwayBrowser/#/R-MMU-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Mus musculus 30616 R-MMU-5674496 https://reactome.org/PathwayBrowser/#/R-MMU-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Mus musculus 30616 R-MMU-5675194 https://reactome.org/PathwayBrowser/#/R-MMU-5675194 Activated MAPK phosphorylates RAF1 IEA Mus musculus 30616 R-MMU-5675198 https://reactome.org/PathwayBrowser/#/R-MMU-5675198 Activated MAPKs phosphorylate BRAF IEA Mus musculus 30616 R-MMU-5675868 https://reactome.org/PathwayBrowser/#/R-MMU-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Mus musculus 30616 R-MMU-5678706 https://reactome.org/PathwayBrowser/#/R-MMU-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Mus musculus 30616 R-MMU-5678863 https://reactome.org/PathwayBrowser/#/R-MMU-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-5679041 https://reactome.org/PathwayBrowser/#/R-MMU-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-5679205 https://reactome.org/PathwayBrowser/#/R-MMU-5679205 ULK1 phosphorylates Beclin-1 IEA Mus musculus 30616 R-MMU-5682026 https://reactome.org/PathwayBrowser/#/R-MMU-5682026 MRN bound to shortened telomeres activates ATM IEA Mus musculus 30616 R-MMU-5682101 https://reactome.org/PathwayBrowser/#/R-MMU-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Mus musculus 30616 R-MMU-5682285 https://reactome.org/PathwayBrowser/#/R-MMU-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-5682598 https://reactome.org/PathwayBrowser/#/R-MMU-5682598 ATM phosphorylates HERC2 IEA Mus musculus 30616 R-MMU-5682983 https://reactome.org/PathwayBrowser/#/R-MMU-5682983 ATM phosphorylates WHSC1 IEA Mus musculus 30616 R-MMU-5683425 https://reactome.org/PathwayBrowser/#/R-MMU-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Mus musculus 30616 R-MMU-5683714 https://reactome.org/PathwayBrowser/#/R-MMU-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Mus musculus 30616 R-MMU-5683792 https://reactome.org/PathwayBrowser/#/R-MMU-5683792 p-T68-CHEK2 autophosphorylates IEA Mus musculus 30616 R-MMU-5683801 https://reactome.org/PathwayBrowser/#/R-MMU-5683801 CHEK2 phosphorylates BRCA1 IEA Mus musculus 30616 R-MMU-5683930 https://reactome.org/PathwayBrowser/#/R-MMU-5683930 WICH phosphorylates H2AFX on Y142 IEA Mus musculus 30616 R-MMU-5683964 https://reactome.org/PathwayBrowser/#/R-MMU-5683964 ATM phosphorylates EYA1-4 IEA Mus musculus 30616 R-MMU-5684096 https://reactome.org/PathwayBrowser/#/R-MMU-5684096 CDK2 phosphorylates RBBP8 IEA Mus musculus 30616 R-MMU-5684140 https://reactome.org/PathwayBrowser/#/R-MMU-5684140 ATM phosphorylates RBBP8 IEA Mus musculus 30616 R-MMU-5684261 https://reactome.org/PathwayBrowser/#/R-MMU-5684261 MAP3K8 is phosphorylated IEA Mus musculus 30616 R-MMU-5684267 https://reactome.org/PathwayBrowser/#/R-MMU-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex IEA Mus musculus 30616 R-MMU-5684275 https://reactome.org/PathwayBrowser/#/R-MMU-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 IEA Mus musculus 30616 R-MMU-5684806 https://reactome.org/PathwayBrowser/#/R-MMU-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN IEA Mus musculus 30616 R-MMU-5684862 https://reactome.org/PathwayBrowser/#/R-MMU-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Mus musculus 30616 R-MMU-5684887 https://reactome.org/PathwayBrowser/#/R-MMU-5684887 Activation of CHEK1 at resected DNA DSBs IEA Mus musculus 30616 R-MMU-5685156 https://reactome.org/PathwayBrowser/#/R-MMU-5685156 ATR phosphorylates RPA2 IEA Mus musculus 30616 R-MMU-5685230 https://reactome.org/PathwayBrowser/#/R-MMU-5685230 CHEK1 phosphorylates RAD51 IEA Mus musculus 30616 R-MMU-5686578 https://reactome.org/PathwayBrowser/#/R-MMU-5686578 Activated ATM phosphorylates ABL1 IEA Mus musculus 30616 R-MMU-5686587 https://reactome.org/PathwayBrowser/#/R-MMU-5686587 ABL1 phosphorylates RAD52 IEA Mus musculus 30616 R-MMU-5686704 https://reactome.org/PathwayBrowser/#/R-MMU-5686704 Activated ATM phosphorylates DCLRE1C IEA Mus musculus 30616 R-MMU-5687086 https://reactome.org/PathwayBrowser/#/R-MMU-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Mus musculus 30616 R-MMU-5687088 https://reactome.org/PathwayBrowser/#/R-MMU-5687088 PKA phosphorylates MAPKAPK5 IEA Mus musculus 30616 R-MMU-5687090 https://reactome.org/PathwayBrowser/#/R-MMU-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Mus musculus 30616 R-MMU-5687094 https://reactome.org/PathwayBrowser/#/R-MMU-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Mus musculus 30616 R-MMU-5687101 https://reactome.org/PathwayBrowser/#/R-MMU-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Mus musculus 30616 R-MMU-5687121 https://reactome.org/PathwayBrowser/#/R-MMU-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Mus musculus 30616 R-MMU-5687183 https://reactome.org/PathwayBrowser/#/R-MMU-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Mus musculus 30616 R-MMU-5690250 https://reactome.org/PathwayBrowser/#/R-MMU-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Mus musculus 30616 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus 30616 R-MMU-5690996 https://reactome.org/PathwayBrowser/#/R-MMU-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Mus musculus 30616 R-MMU-5692462 https://reactome.org/PathwayBrowser/#/R-MMU-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Mus musculus 30616 R-MMU-5692480 https://reactome.org/PathwayBrowser/#/R-MMU-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Mus musculus 30616 R-MMU-5692755 https://reactome.org/PathwayBrowser/#/R-MMU-5692755 CDK1 phosphorylates MAPK6 IEA Mus musculus 30616 R-MMU-5692768 https://reactome.org/PathwayBrowser/#/R-MMU-5692768 MAPKAPK5 phosphorylates KALRN IEA Mus musculus 30616 R-MMU-5692775 https://reactome.org/PathwayBrowser/#/R-MMU-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Mus musculus 30616 R-MMU-5692779 https://reactome.org/PathwayBrowser/#/R-MMU-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Mus musculus 30616 R-MMU-5693148 https://reactome.org/PathwayBrowser/#/R-MMU-5693148 BCKDK phosphorylates BCKDH IEA Mus musculus 30616 R-MMU-5693536 https://reactome.org/PathwayBrowser/#/R-MMU-5693536 ATM phosphorylates MDC1 IEA Mus musculus 30616 R-MMU-5693540 https://reactome.org/PathwayBrowser/#/R-MMU-5693540 MRN activates ATM IEA Mus musculus 30616 R-MMU-5693549 https://reactome.org/PathwayBrowser/#/R-MMU-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Mus musculus 30616 R-MMU-5693551 https://reactome.org/PathwayBrowser/#/R-MMU-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Mus musculus 30616 R-MMU-5693575 https://reactome.org/PathwayBrowser/#/R-MMU-5693575 DNA-PKcs autophosphorylates IEA Mus musculus 30616 R-MMU-5693598 https://reactome.org/PathwayBrowser/#/R-MMU-5693598 ATM phosphorylates NBN IEA Mus musculus 30616 R-MMU-5693609 https://reactome.org/PathwayBrowser/#/R-MMU-5693609 ATM phosphorylates TP53 at S15 IEA Mus musculus 30616 R-MMU-5694425 https://reactome.org/PathwayBrowser/#/R-MMU-5694425 NSF ATPase activity dissociates cis-SNARE IEA Mus musculus 30616 R-MMU-5694441 https://reactome.org/PathwayBrowser/#/R-MMU-5694441 CSNK1D phosphorylates SEC23 IEA Mus musculus 30616 R-MMU-5694494 https://reactome.org/PathwayBrowser/#/R-MMU-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Mus musculus 30616 R-MMU-5695957 https://reactome.org/PathwayBrowser/#/R-MMU-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Mus musculus 30616 R-MMU-5696004 https://reactome.org/PathwayBrowser/#/R-MMU-5696004 ACSF2 ligates CoA-SH to MCFA IEA Mus musculus 30616 R-MMU-5696007 https://reactome.org/PathwayBrowser/#/R-MMU-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Mus musculus 30616 R-MMU-5696074 https://reactome.org/PathwayBrowser/#/R-MMU-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Mus musculus 30616 R-MMU-5696839 https://reactome.org/PathwayBrowser/#/R-MMU-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Mus musculus 30616 R-MMU-6782131 https://reactome.org/PathwayBrowser/#/R-MMU-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Mus musculus 30616 R-MMU-6784006 https://reactome.org/PathwayBrowser/#/R-MMU-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Mus musculus 30616 R-MMU-6784319 https://reactome.org/PathwayBrowser/#/R-MMU-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Mus musculus 30616 R-MMU-6784324 https://reactome.org/PathwayBrowser/#/R-MMU-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Mus musculus 30616 R-MMU-6786050 https://reactome.org/PathwayBrowser/#/R-MMU-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Mus musculus 30616 R-MMU-6786095 https://reactome.org/PathwayBrowser/#/R-MMU-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Mus musculus 30616 R-MMU-6786096 https://reactome.org/PathwayBrowser/#/R-MMU-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Mus musculus 30616 R-MMU-6786245 https://reactome.org/PathwayBrowser/#/R-MMU-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Mus musculus 30616 R-MMU-6787540 https://reactome.org/PathwayBrowser/#/R-MMU-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Mus musculus 30616 R-MMU-6788392 https://reactome.org/PathwayBrowser/#/R-MMU-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Mus musculus 30616 R-MMU-6788582 https://reactome.org/PathwayBrowser/#/R-MMU-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Mus musculus 30616 R-MMU-6788798 https://reactome.org/PathwayBrowser/#/R-MMU-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 30616 R-MMU-6788810 https://reactome.org/PathwayBrowser/#/R-MMU-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 30616 R-MMU-6788855 https://reactome.org/PathwayBrowser/#/R-MMU-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Mus musculus 30616 R-MMU-6788867 https://reactome.org/PathwayBrowser/#/R-MMU-6788867 FN3K phosphorylates ketosamines IEA Mus musculus 30616 R-MMU-6790089 https://reactome.org/PathwayBrowser/#/R-MMU-6790089 Hvem induses Btla phosphorylation TAS Mus musculus 30616 R-MMU-6793661 https://reactome.org/PathwayBrowser/#/R-MMU-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Mus musculus 30616 R-MMU-6795290 https://reactome.org/PathwayBrowser/#/R-MMU-6795290 TORC2 complex phosphorylates SGK1 IEA Mus musculus 30616 R-MMU-6795460 https://reactome.org/PathwayBrowser/#/R-MMU-6795460 SGK1 phosphorylates MDM2 IEA Mus musculus 30616 R-MMU-6795473 https://reactome.org/PathwayBrowser/#/R-MMU-6795473 PDPK1 phosphorylates SGK1 IEA Mus musculus 30616 R-MMU-6797606 https://reactome.org/PathwayBrowser/#/R-MMU-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Mus musculus 30616 R-MMU-6798174 https://reactome.org/PathwayBrowser/#/R-MMU-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Mus musculus 30616 R-MMU-6798372 https://reactome.org/PathwayBrowser/#/R-MMU-6798372 ATM phosphorylates DYRK2 IEA Mus musculus 30616 R-MMU-6798374 https://reactome.org/PathwayBrowser/#/R-MMU-6798374 DYRK2 phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6799097 https://reactome.org/PathwayBrowser/#/R-MMU-6799097 ATM phosphorylates ZNF420 IEA Mus musculus 30616 R-MMU-6799246 https://reactome.org/PathwayBrowser/#/R-MMU-6799246 CHEK1 phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6799332 https://reactome.org/PathwayBrowser/#/R-MMU-6799332 ATR phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6799409 https://reactome.org/PathwayBrowser/#/R-MMU-6799409 HIPK2 phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6799495 https://reactome.org/PathwayBrowser/#/R-MMU-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Mus musculus 30616 R-MMU-6800490 https://reactome.org/PathwayBrowser/#/R-MMU-6800490 ATM phosphorylates PIDD1 IEA Mus musculus 30616 R-MMU-6801342 https://reactome.org/PathwayBrowser/#/R-MMU-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Mus musculus 30616 R-MMU-6801456 https://reactome.org/PathwayBrowser/#/R-MMU-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Mus musculus 30616 R-MMU-6801666 https://reactome.org/PathwayBrowser/#/R-MMU-6801666 PLK2 phosphorylates CENPJ IEA Mus musculus 30616 R-MMU-6801675 https://reactome.org/PathwayBrowser/#/R-MMU-6801675 PLK2 phosphorylates NPM1 IEA Mus musculus 30616 R-MMU-6802973 https://reactome.org/PathwayBrowser/#/R-MMU-6802973 PLK3 phosphorylates CDC25C IEA Mus musculus 30616 R-MMU-6803545 https://reactome.org/PathwayBrowser/#/R-MMU-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Mus musculus 30616 R-MMU-6803771 https://reactome.org/PathwayBrowser/#/R-MMU-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Mus musculus 30616 R-MMU-6804266 https://reactome.org/PathwayBrowser/#/R-MMU-6804266 CHEK2 phosphorylates TTC5 IEA Mus musculus 30616 R-MMU-6804276 https://reactome.org/PathwayBrowser/#/R-MMU-6804276 ATM phosphorylates TTC5 IEA Mus musculus 30616 R-MMU-6804596 https://reactome.org/PathwayBrowser/#/R-MMU-6804596 APAF1:CYCS binds APIP IEA Mus musculus 30616 R-MMU-6804642 https://reactome.org/PathwayBrowser/#/R-MMU-6804642 Uaca binds apoptosome TAS Mus musculus 30616 R-MMU-6804955 https://reactome.org/PathwayBrowser/#/R-MMU-6804955 ATM phosphorylates MDM2 IEA Mus musculus 30616 R-MMU-6805059 https://reactome.org/PathwayBrowser/#/R-MMU-6805059 CK2:FACT phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6805103 https://reactome.org/PathwayBrowser/#/R-MMU-6805103 AURKA phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6805109 https://reactome.org/PathwayBrowser/#/R-MMU-6805109 CDK2 phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6805126 https://reactome.org/PathwayBrowser/#/R-MMU-6805126 AURKB phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6805276 https://reactome.org/PathwayBrowser/#/R-MMU-6805276 CDK5 phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6805285 https://reactome.org/PathwayBrowser/#/R-MMU-6805285 PLK3 phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6805399 https://reactome.org/PathwayBrowser/#/R-MMU-6805399 TAF1 phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6805470 https://reactome.org/PathwayBrowser/#/R-MMU-6805470 AMPK phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6805479 https://reactome.org/PathwayBrowser/#/R-MMU-6805479 TP53RK phosphorylates TP53 IEA Mus musculus 30616 R-MMU-6805640 https://reactome.org/PathwayBrowser/#/R-MMU-6805640 AKT phosphorylates KAT6A IEA Mus musculus 30616 R-MMU-6805785 https://reactome.org/PathwayBrowser/#/R-MMU-6805785 AKT phosphorylates PHF20 IEA Mus musculus 30616 R-MMU-6806877 https://reactome.org/PathwayBrowser/#/R-MMU-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Mus musculus 30616 R-MMU-6806967 https://reactome.org/PathwayBrowser/#/R-MMU-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Mus musculus 30616 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 30616 R-MMU-6807868 https://reactome.org/PathwayBrowser/#/R-MMU-6807868 GBF1 stimulates ARF nucleotide exchange IEA Mus musculus 30616 R-MMU-6809015 https://reactome.org/PathwayBrowser/#/R-MMU-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Mus musculus 30616 R-MMU-6810233 https://reactome.org/PathwayBrowser/#/R-MMU-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Mus musculus 30616 R-MMU-6811422 https://reactome.org/PathwayBrowser/#/R-MMU-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Mus musculus 30616 R-MMU-6811454 https://reactome.org/PathwayBrowser/#/R-MMU-6811454 MAPKs phosphorylate PP2A IEA Mus musculus 30616 R-MMU-6811522 https://reactome.org/PathwayBrowser/#/R-MMU-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Mus musculus 30616 R-MMU-6814120 https://reactome.org/PathwayBrowser/#/R-MMU-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Mus musculus 30616 R-MMU-6814124 https://reactome.org/PathwayBrowser/#/R-MMU-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Mus musculus 30616 R-MMU-6814409 https://reactome.org/PathwayBrowser/#/R-MMU-6814409 CK2 phosphorylates PDCL IEA Mus musculus 30616 R-MMU-6814549 https://reactome.org/PathwayBrowser/#/R-MMU-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Mus musculus 30616 R-MMU-6814559 https://reactome.org/PathwayBrowser/#/R-MMU-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Mus musculus 30616 R-MMU-6814670 https://reactome.org/PathwayBrowser/#/R-MMU-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Mus musculus 30616 R-MMU-6814675 https://reactome.org/PathwayBrowser/#/R-MMU-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Mus musculus 30616 R-MMU-6814683 https://reactome.org/PathwayBrowser/#/R-MMU-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Mus musculus 30616 R-MMU-68610 https://reactome.org/PathwayBrowser/#/R-MMU-68610 Formation of ORC(2-5) complex IEA Mus musculus 30616 R-MMU-68944 https://reactome.org/PathwayBrowser/#/R-MMU-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Mus musculus 30616 R-MMU-68954 https://reactome.org/PathwayBrowser/#/R-MMU-68954 Mcm2-7 is phosphorylated by DDK IEA Mus musculus 30616 R-MMU-69005 https://reactome.org/PathwayBrowser/#/R-MMU-69005 Cdc6 protein is phosphorylated by CDK IEA Mus musculus 30616 R-MMU-69015 https://reactome.org/PathwayBrowser/#/R-MMU-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Mus musculus 30616 R-MMU-69063 https://reactome.org/PathwayBrowser/#/R-MMU-69063 Loading of PCNA - Sliding Clamp Formation IEA Mus musculus 30616 R-MMU-69195 https://reactome.org/PathwayBrowser/#/R-MMU-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Mus musculus 30616 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 30616 R-MMU-69604 https://reactome.org/PathwayBrowser/#/R-MMU-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Mus musculus 30616 R-MMU-69608 https://reactome.org/PathwayBrowser/#/R-MMU-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Mus musculus 30616 R-MMU-69685 https://reactome.org/PathwayBrowser/#/R-MMU-69685 CHEK2 phosphorylates TP53 IEA Mus musculus 30616 R-MMU-69891 https://reactome.org/PathwayBrowser/#/R-MMU-69891 Phosphorylation and activation of CHEK2 by ATM IEA Mus musculus 30616 R-MMU-70333 https://reactome.org/PathwayBrowser/#/R-MMU-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Mus musculus 30616 R-MMU-70349 https://reactome.org/PathwayBrowser/#/R-MMU-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Mus musculus 30616 R-MMU-70355 https://reactome.org/PathwayBrowser/#/R-MMU-70355 GALK1 phosphorylates Gal to Gal1P IEA Mus musculus 30616 R-MMU-70420 https://reactome.org/PathwayBrowser/#/R-MMU-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Mus musculus 30616 R-MMU-70467 https://reactome.org/PathwayBrowser/#/R-MMU-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Mus musculus 30616 R-MMU-70486 https://reactome.org/PathwayBrowser/#/R-MMU-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Mus musculus 30616 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 30616 R-MMU-70555 https://reactome.org/PathwayBrowser/#/R-MMU-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Mus musculus 30616 R-MMU-70577 https://reactome.org/PathwayBrowser/#/R-MMU-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Mus musculus 30616 R-MMU-70599 https://reactome.org/PathwayBrowser/#/R-MMU-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Mus musculus 30616 R-MMU-70606 https://reactome.org/PathwayBrowser/#/R-MMU-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Mus musculus 30616 R-MMU-70773 https://reactome.org/PathwayBrowser/#/R-MMU-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Mus musculus 30616 R-MMU-70967 https://reactome.org/PathwayBrowser/#/R-MMU-70967 IDH3 complex decarboxylates isocitrate IEA Mus musculus 30616 R-MMU-70997 https://reactome.org/PathwayBrowser/#/R-MMU-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Mus musculus 30616 R-MMU-71031 https://reactome.org/PathwayBrowser/#/R-MMU-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Mus musculus 30616 R-MMU-71401 https://reactome.org/PathwayBrowser/#/R-MMU-71401 OGDH dimer decarboxylates 2-OG IEA Mus musculus 30616 R-MMU-71541 https://reactome.org/PathwayBrowser/#/R-MMU-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Mus musculus 30616 R-MMU-71588 https://reactome.org/PathwayBrowser/#/R-MMU-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Mus musculus 30616 R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 30616 R-MMU-71735 https://reactome.org/PathwayBrowser/#/R-MMU-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Mus musculus 30616 R-MMU-71802 https://reactome.org/PathwayBrowser/#/R-MMU-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Mus musculus 30616 R-MMU-71850 https://reactome.org/PathwayBrowser/#/R-MMU-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Mus musculus 30616 R-MMU-72180 https://reactome.org/PathwayBrowser/#/R-MMU-72180 Cleavage of mRNA at the 3'-end IEA Mus musculus 30616 R-MMU-72185 https://reactome.org/PathwayBrowser/#/R-MMU-72185 mRNA polyadenylation IEA Mus musculus 30616 R-MMU-72621 https://reactome.org/PathwayBrowser/#/R-MMU-72621 Ribosomal scanning IEA Mus musculus 30616 R-MMU-72647 https://reactome.org/PathwayBrowser/#/R-MMU-72647 Cap-bound mRNA is activated by helicases IEA Mus musculus 30616 R-MMU-727819 https://reactome.org/PathwayBrowser/#/R-MMU-727819 TAK1 phosphorylates MKK6 IEA Mus musculus 30616 R-MMU-73548 https://reactome.org/PathwayBrowser/#/R-MMU-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Mus musculus 30616 R-MMU-73577 https://reactome.org/PathwayBrowser/#/R-MMU-73577 CAD hexamer transforms L-Gln to CAP IEA Mus musculus 30616 R-MMU-73580 https://reactome.org/PathwayBrowser/#/R-MMU-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Mus musculus 30616 R-MMU-73598 https://reactome.org/PathwayBrowser/#/R-MMU-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Mus musculus 30616 R-MMU-73599 https://reactome.org/PathwayBrowser/#/R-MMU-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Mus musculus 30616 R-MMU-73632 https://reactome.org/PathwayBrowser/#/R-MMU-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Mus musculus 30616 R-MMU-73635 https://reactome.org/PathwayBrowser/#/R-MMU-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Mus musculus 30616 R-MMU-73647 https://reactome.org/PathwayBrowser/#/R-MMU-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Mus musculus 30616 R-MMU-73722 https://reactome.org/PathwayBrowser/#/R-MMU-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Mus musculus 30616 R-MMU-73788 https://reactome.org/PathwayBrowser/#/R-MMU-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Mus musculus 30616 R-MMU-73792 https://reactome.org/PathwayBrowser/#/R-MMU-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Mus musculus 30616 R-MMU-73805 https://reactome.org/PathwayBrowser/#/R-MMU-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Mus musculus 30616 R-MMU-73810 https://reactome.org/PathwayBrowser/#/R-MMU-73810 FGAM + ATP => AIR + ADP + Pi IEA Mus musculus 30616 R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 30616 R-MMU-73814 https://reactome.org/PathwayBrowser/#/R-MMU-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Mus musculus 30616 R-MMU-74207 https://reactome.org/PathwayBrowser/#/R-MMU-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Mus musculus 30616 R-MMU-74220 https://reactome.org/PathwayBrowser/#/R-MMU-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Mus musculus 30616 R-MMU-74711 https://reactome.org/PathwayBrowser/#/R-MMU-74711 Phosphorylation of IRS IEA Mus musculus 30616 R-MMU-74715 https://reactome.org/PathwayBrowser/#/R-MMU-74715 Autophosphorylation of insulin receptor IEA Mus musculus 30616 R-MMU-74742 https://reactome.org/PathwayBrowser/#/R-MMU-74742 Phosphorylation of SHC1 IEA Mus musculus 30616 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 30616 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 30616 R-MMU-75010 https://reactome.org/PathwayBrowser/#/R-MMU-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Mus musculus 30616 R-MMU-75125 https://reactome.org/PathwayBrowser/#/R-MMU-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Mus musculus 30616 R-MMU-75126 https://reactome.org/PathwayBrowser/#/R-MMU-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Mus musculus 30616 R-MMU-75809 https://reactome.org/PathwayBrowser/#/R-MMU-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Mus musculus 30616 R-MMU-75848 https://reactome.org/PathwayBrowser/#/R-MMU-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Mus musculus 30616 R-MMU-75851 https://reactome.org/PathwayBrowser/#/R-MMU-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 30616 R-MMU-75887 https://reactome.org/PathwayBrowser/#/R-MMU-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Mus musculus 30616 R-MMU-75949 https://reactome.org/PathwayBrowser/#/R-MMU-75949 RNA Polymerase II Promoter Opening: First Transition IEA Mus musculus 30616 R-MMU-77071 https://reactome.org/PathwayBrowser/#/R-MMU-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Mus musculus 30616 R-MMU-844438 https://reactome.org/PathwayBrowser/#/R-MMU-844438 NLRP1 oligomerizes IEA Mus musculus 30616 R-MMU-873918 https://reactome.org/PathwayBrowser/#/R-MMU-873918 Transphosphorylation of JAK1 IEA Mus musculus 30616 R-MMU-873919 https://reactome.org/PathwayBrowser/#/R-MMU-873919 Phosphorylation of JAK2 IEA Mus musculus 30616 R-MMU-873922 https://reactome.org/PathwayBrowser/#/R-MMU-873922 Phosphorylation of STAT1 by JAK kinases IEA Mus musculus 30616 R-MMU-873924 https://reactome.org/PathwayBrowser/#/R-MMU-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Mus musculus 30616 R-MMU-877187 https://reactome.org/PathwayBrowser/#/R-MMU-877187 P2X7 mediates loss of intracellular K+ IEA Mus musculus 30616 R-MMU-877198 https://reactome.org/PathwayBrowser/#/R-MMU-877198 P2X7 mediates membrane pores that include pannexin-1 IEA Mus musculus 30616 R-MMU-879222 https://reactome.org/PathwayBrowser/#/R-MMU-879222 MDP:NLRP1 binds ATP IEA Mus musculus 30616 R-MMU-879907 https://reactome.org/PathwayBrowser/#/R-MMU-879907 Tyrosine kinases phosphorylate the receptor IEA Mus musculus 30616 R-MMU-879909 https://reactome.org/PathwayBrowser/#/R-MMU-879909 Activation of STAT5a/b by JAK2 IEA Mus musculus 30616 R-MMU-879910 https://reactome.org/PathwayBrowser/#/R-MMU-879910 JAK2 is phosphorylated, activated IEA Mus musculus 30616 R-MMU-8847638 https://reactome.org/PathwayBrowser/#/R-MMU-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Mus musculus 30616 R-MMU-8847977 https://reactome.org/PathwayBrowser/#/R-MMU-8847977 FRK phosphorylates PTEN IEA Mus musculus 30616 R-MMU-8848005 https://reactome.org/PathwayBrowser/#/R-MMU-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Mus musculus 30616 R-MMU-8848053 https://reactome.org/PathwayBrowser/#/R-MMU-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Mus musculus 30616 R-MMU-8848077 https://reactome.org/PathwayBrowser/#/R-MMU-8848077 PTK6 phosphorylates STAP2 IEA Mus musculus 30616 R-MMU-8848124 https://reactome.org/PathwayBrowser/#/R-MMU-8848124 PTK6 phosphorylates STAT3 IEA Mus musculus 30616 R-MMU-8848436 https://reactome.org/PathwayBrowser/#/R-MMU-8848436 PTK6 phosphorylates CDKN1B IEA Mus musculus 30616 R-MMU-8848606 https://reactome.org/PathwayBrowser/#/R-MMU-8848606 PTK6 phosphorylates PXN IEA Mus musculus 30616 R-MMU-8848726 https://reactome.org/PathwayBrowser/#/R-MMU-8848726 PTK6 phosphorylates BCAR1 IEA Mus musculus 30616 R-MMU-8848758 https://reactome.org/PathwayBrowser/#/R-MMU-8848758 PTK6 phosphorylates AKT1 IEA Mus musculus 30616 R-MMU-8848776 https://reactome.org/PathwayBrowser/#/R-MMU-8848776 PTK6 phosphorylates DOK1 IEA Mus musculus 30616 R-MMU-8848818 https://reactome.org/PathwayBrowser/#/R-MMU-8848818 PTK6 phosphorylates CBL IEA Mus musculus 30616 R-MMU-8848873 https://reactome.org/PathwayBrowser/#/R-MMU-8848873 PTK6 phosphorylates ARAP1 IEA Mus musculus 30616 R-MMU-8848975 https://reactome.org/PathwayBrowser/#/R-MMU-8848975 PTK6 phosphorylates KHDRBS1 IEA Mus musculus 30616 R-MMU-8849032 https://reactome.org/PathwayBrowser/#/R-MMU-8849032 PTK6 phosphorylates KHDRBS2 IEA Mus musculus 30616 R-MMU-8849042 https://reactome.org/PathwayBrowser/#/R-MMU-8849042 PTK6 phosphorylates KHDRBS3 IEA Mus musculus 30616 R-MMU-8849068 https://reactome.org/PathwayBrowser/#/R-MMU-8849068 PTK6 phosphorylates ARHGAP35 IEA Mus musculus 30616 R-MMU-8849102 https://reactome.org/PathwayBrowser/#/R-MMU-8849102 SRMS phosphorylates PTK6 IEA Mus musculus 30616 R-MMU-8849157 https://reactome.org/PathwayBrowser/#/R-MMU-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Mus musculus 30616 R-MMU-8849353 https://reactome.org/PathwayBrowser/#/R-MMU-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Mus musculus 30616 R-MMU-8849463 https://reactome.org/PathwayBrowser/#/R-MMU-8849463 PTK6 phosphorylates SFPQ IEA Mus musculus 30616 R-MMU-8850945 https://reactome.org/PathwayBrowser/#/R-MMU-8850945 Casein kinase II phosphorylates PTEN IEA Mus musculus 30616 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 30616 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 30616 R-MMU-8851797 https://reactome.org/PathwayBrowser/#/R-MMU-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Mus musculus 30616 R-MMU-8851890 https://reactome.org/PathwayBrowser/#/R-MMU-8851890 MET phosphorylates SHC1-2 IEA Mus musculus 30616 R-MMU-8851933 https://reactome.org/PathwayBrowser/#/R-MMU-8851933 MET phosphorylates GAB1 IEA Mus musculus 30616 R-MMU-8852019 https://reactome.org/PathwayBrowser/#/R-MMU-8852019 MET bound PI3K generates PIP3 IEA Mus musculus 30616 R-MMU-8852128 https://reactome.org/PathwayBrowser/#/R-MMU-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Mus musculus 30616 R-MMU-8852131 https://reactome.org/PathwayBrowser/#/R-MMU-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Mus musculus 30616 R-MMU-8852132 https://reactome.org/PathwayBrowser/#/R-MMU-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Mus musculus 30616 R-MMU-8852134 https://reactome.org/PathwayBrowser/#/R-MMU-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Mus musculus 30616 R-MMU-8852306 https://reactome.org/PathwayBrowser/#/R-MMU-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Mus musculus 30616 R-MMU-8852317 https://reactome.org/PathwayBrowser/#/R-MMU-8852317 PLK1 phosphorylates GTSE1 IEA Mus musculus 30616 R-MMU-8852552 https://reactome.org/PathwayBrowser/#/R-MMU-8852552 MST1R autophosphorylates IEA Mus musculus 30616 R-MMU-8853419 https://reactome.org/PathwayBrowser/#/R-MMU-8853419 TPX2 promotes AURKA autophosphorylation IEA Mus musculus 30616 R-MMU-8853444 https://reactome.org/PathwayBrowser/#/R-MMU-8853444 AURKA phosphorylates PHLDA1 IEA Mus musculus 30616 R-MMU-8853774 https://reactome.org/PathwayBrowser/#/R-MMU-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Mus musculus 30616 R-MMU-8853792 https://reactome.org/PathwayBrowser/#/R-MMU-8853792 RET tyrosine phosphorylation IEA Mus musculus 30616 R-MMU-8854908 https://reactome.org/PathwayBrowser/#/R-MMU-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Mus musculus 30616 R-MMU-8855237 https://reactome.org/PathwayBrowser/#/R-MMU-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Mus musculus 30616 R-MMU-8856813 https://reactome.org/PathwayBrowser/#/R-MMU-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Mus musculus 30616 R-MMU-8857555 https://reactome.org/PathwayBrowser/#/R-MMU-8857555 EGFR phosphorylates GPNMB IEA Mus musculus 30616 R-MMU-8857577 https://reactome.org/PathwayBrowser/#/R-MMU-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Mus musculus 30616 R-MMU-8857583 https://reactome.org/PathwayBrowser/#/R-MMU-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Mus musculus 30616 R-MMU-8857925 https://reactome.org/PathwayBrowser/#/R-MMU-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Mus musculus 30616 R-MMU-8865774 https://reactome.org/PathwayBrowser/#/R-MMU-8865774 TTLLs polyglutamylate tubulin IEA Mus musculus 30616 R-MMU-8866268 https://reactome.org/PathwayBrowser/#/R-MMU-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Mus musculus 30616 R-MMU-8866405 https://reactome.org/PathwayBrowser/#/R-MMU-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 30616 R-MMU-8866542 https://reactome.org/PathwayBrowser/#/R-MMU-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Mus musculus 30616 R-MMU-8867041 https://reactome.org/PathwayBrowser/#/R-MMU-8867041 EGFR phosphorylates EPS15 IEA Mus musculus 30616 R-MMU-8867370 https://reactome.org/PathwayBrowser/#/R-MMU-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Mus musculus 30616 R-MMU-8868066 https://reactome.org/PathwayBrowser/#/R-MMU-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Mus musculus 30616 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 30616 R-MMU-8868118 https://reactome.org/PathwayBrowser/#/R-MMU-8868118 MAPK12 phosphorylates PTPN3 IEA Mus musculus 30616 R-MMU-8868236 https://reactome.org/PathwayBrowser/#/R-MMU-8868236 BAR domain proteins recruit dynamin IEA Mus musculus 30616 R-MMU-8868331 https://reactome.org/PathwayBrowser/#/R-MMU-8868331 Cdk5:p25 phosphorylates Golga2 TAS Mus musculus 30616 R-MMU-8868356 https://reactome.org/PathwayBrowser/#/R-MMU-8868356 Cdk5:p25 phosphorylates lamin A TAS Mus musculus 30616 R-MMU-8868383 https://reactome.org/PathwayBrowser/#/R-MMU-8868383 Cdk5:p25 phosphorylates lamin B1 TAS Mus musculus 30616 R-MMU-8868583 https://reactome.org/PathwayBrowser/#/R-MMU-8868583 Cdk5:p25 phosphorylates Prdx1 TAS Mus musculus 30616 R-MMU-8868589 https://reactome.org/PathwayBrowser/#/R-MMU-8868589 Cdk5:p25 phosphorylates Prdx2 TAS Mus musculus 30616 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 30616 R-MMU-8868651 https://reactome.org/PathwayBrowser/#/R-MMU-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Mus musculus 30616 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 30616 R-MMU-8868659 https://reactome.org/PathwayBrowser/#/R-MMU-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Mus musculus 30616 R-MMU-8868660 https://reactome.org/PathwayBrowser/#/R-MMU-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Mus musculus 30616 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 30616 R-MMU-8868677 https://reactome.org/PathwayBrowser/#/R-MMU-8868677 Cdk5:p25 phosphorylates Jun TAS Mus musculus 30616 R-MMU-8869606 https://reactome.org/PathwayBrowser/#/R-MMU-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Mus musculus 30616 R-MMU-8869607 https://reactome.org/PathwayBrowser/#/R-MMU-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Mus musculus 30616 R-MMU-8869627 https://reactome.org/PathwayBrowser/#/R-MMU-8869627 NMRK2 phosphorylates NR to yield NMN IEA Mus musculus 30616 R-MMU-8869633 https://reactome.org/PathwayBrowser/#/R-MMU-8869633 NMRK1 phosphorylates NR to yield NMN IEA Mus musculus 30616 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 30616 R-MMU-8871194 https://reactome.org/PathwayBrowser/#/R-MMU-8871194 RAB5 and GAPVD1 bind AP-2 IEA Mus musculus 30616 R-MMU-8871373 https://reactome.org/PathwayBrowser/#/R-MMU-8871373 BMX phosphorylates RUFY1 IEA Mus musculus 30616 R-MMU-8873929 https://reactome.org/PathwayBrowser/#/R-MMU-8873929 Casein kinase II phosphorylates STARD10 IEA Mus musculus 30616 R-MMU-8874078 https://reactome.org/PathwayBrowser/#/R-MMU-8874078 PTK2 autophosphorylates IEA Mus musculus 30616 R-MMU-8874080 https://reactome.org/PathwayBrowser/#/R-MMU-8874080 SRC phosphorylates PTK2 IEA Mus musculus 30616 R-MMU-8874082 https://reactome.org/PathwayBrowser/#/R-MMU-8874082 MET phosphorylates PTK2 IEA Mus musculus 30616 R-MMU-8875039 https://reactome.org/PathwayBrowser/#/R-MMU-8875039 Acsm3 ligates CoA to BUT TAS Mus musculus 30616 R-MMU-8875071 https://reactome.org/PathwayBrowser/#/R-MMU-8875071 ACSS3 ligates CoA to CH3COO- IEA Mus musculus 30616 R-MMU-8875095 https://reactome.org/PathwayBrowser/#/R-MMU-8875095 Slc27a3 ligates CoA to VLCFA TAS Mus musculus 30616 R-MMU-8875451 https://reactome.org/PathwayBrowser/#/R-MMU-8875451 MET phosphorylates CBL IEA Mus musculus 30616 R-MMU-8875817 https://reactome.org/PathwayBrowser/#/R-MMU-8875817 MET phosphorylates STAT3 IEA Mus musculus 30616 R-MMU-8876446 https://reactome.org/PathwayBrowser/#/R-MMU-8876446 p-ULK1 phosphorylates DENND3 IEA Mus musculus 30616 R-MMU-8876889 https://reactome.org/PathwayBrowser/#/R-MMU-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 30616 R-MMU-8877691 https://reactome.org/PathwayBrowser/#/R-MMU-8877691 MAP2K6 phosphorylates PIP4K2B IEA Mus musculus 30616 R-MMU-8878050 https://reactome.org/PathwayBrowser/#/R-MMU-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Mus musculus 30616 R-MMU-8878054 https://reactome.org/PathwayBrowser/#/R-MMU-8878054 HIPK2 phosphorylates RUNX1 IEA Mus musculus 30616 R-MMU-8931653 https://reactome.org/PathwayBrowser/#/R-MMU-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Mus musculus 30616 R-MMU-8932375 https://reactome.org/PathwayBrowser/#/R-MMU-8932375 CK2 phosphorylates Nrf2 TAS Mus musculus 30616 R-MMU-8933446 https://reactome.org/PathwayBrowser/#/R-MMU-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Mus musculus 30616 R-MMU-8934446 https://reactome.org/PathwayBrowser/#/R-MMU-8934446 Activated PKC phosphorylates SHC1 IEA Mus musculus 30616 R-MMU-8937738 https://reactome.org/PathwayBrowser/#/R-MMU-8937738 Src phosphorylates Runx1 TAS Mus musculus 30616 R-MMU-8937807 https://reactome.org/PathwayBrowser/#/R-MMU-8937807 SRC phosphorylates RUNX3 IEA Mus musculus 30616 R-MMU-8939204 https://reactome.org/PathwayBrowser/#/R-MMU-8939204 ESTG binds ESR1:chaperone complex IEA Mus musculus 30616 R-MMU-8939959 https://reactome.org/PathwayBrowser/#/R-MMU-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Mus musculus 30616 R-MMU-8940100 https://reactome.org/PathwayBrowser/#/R-MMU-8940100 CDK1 phosphorylates VCPIP1 IEA Mus musculus 30616 R-MMU-8942575 https://reactome.org/PathwayBrowser/#/R-MMU-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Mus musculus 30616 R-MMU-8942607 https://reactome.org/PathwayBrowser/#/R-MMU-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Mus musculus 30616 R-MMU-8942836 https://reactome.org/PathwayBrowser/#/R-MMU-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Mus musculus 30616 R-MMU-8944454 https://reactome.org/PathwayBrowser/#/R-MMU-8944454 mTORC1 phosphorylates MAF1 IEA Mus musculus 30616 R-MMU-8948039 https://reactome.org/PathwayBrowser/#/R-MMU-8948039 FUNDC1 is phosphorylated by CK2 IEA Mus musculus 30616 R-MMU-8948143 https://reactome.org/PathwayBrowser/#/R-MMU-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Mus musculus 30616 R-MMU-8948146 https://reactome.org/PathwayBrowser/#/R-MMU-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Mus musculus 30616 R-MMU-8948757 https://reactome.org/PathwayBrowser/#/R-MMU-8948757 AKT phosphorylates MKRN1 IEA Mus musculus 30616 R-MMU-8950269 https://reactome.org/PathwayBrowser/#/R-MMU-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Mus musculus 30616 R-MMU-8950340 https://reactome.org/PathwayBrowser/#/R-MMU-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Mus musculus 30616 R-MMU-8950405 https://reactome.org/PathwayBrowser/#/R-MMU-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Mus musculus 30616 R-MMU-8950423 https://reactome.org/PathwayBrowser/#/R-MMU-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Mus musculus 30616 R-MMU-8950453 https://reactome.org/PathwayBrowser/#/R-MMU-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Mus musculus 30616 R-MMU-8950485 https://reactome.org/PathwayBrowser/#/R-MMU-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Mus musculus 30616 R-MMU-8950537 https://reactome.org/PathwayBrowser/#/R-MMU-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Mus musculus 30616 R-MMU-8950612 https://reactome.org/PathwayBrowser/#/R-MMU-8950612 Jak2, Tyk2 in Il12b:Il23a:Il12rb1:Tyk2:Il23r:Jak2 are phosphorylated TAS Mus musculus 30616 R-MMU-8950679 https://reactome.org/PathwayBrowser/#/R-MMU-8950679 Il23r from Il23:Il23 receptor complex is phosphorylated TAS Mus musculus 30616 R-MMU-8950757 https://reactome.org/PathwayBrowser/#/R-MMU-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Mus musculus 30616 R-MMU-8951648 https://reactome.org/PathwayBrowser/#/R-MMU-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Mus musculus 30616 R-MMU-8951656 https://reactome.org/PathwayBrowser/#/R-MMU-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Mus musculus 30616 R-MMU-8952289 https://reactome.org/PathwayBrowser/#/R-MMU-8952289 FAM20C phosphorylates FAM20C substrates IEA Mus musculus 30616 R-MMU-8954327 https://reactome.org/PathwayBrowser/#/R-MMU-8954327 UCKL1 phosphorylates urindine, cytidine IEA Mus musculus 30616 R-MMU-8955030 https://reactome.org/PathwayBrowser/#/R-MMU-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Mus musculus 30616 R-MMU-8955844 https://reactome.org/PathwayBrowser/#/R-MMU-8955844 RBKS phosphorylates ribose to R5P IEA Mus musculus 30616 R-MMU-8956659 https://reactome.org/PathwayBrowser/#/R-MMU-8956659 ABL1 phosphorylates YAP1 IEA Mus musculus 30616 R-MMU-8959510 https://reactome.org/PathwayBrowser/#/R-MMU-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Mus musculus 30616 R-MMU-8959719 https://reactome.org/PathwayBrowser/#/R-MMU-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Mus musculus 30616 R-MMU-8964242 https://reactome.org/PathwayBrowser/#/R-MMU-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Mus musculus 30616 R-MMU-8982163 https://reactome.org/PathwayBrowser/#/R-MMU-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Mus musculus 30616 R-MMU-8983059 https://reactome.org/PathwayBrowser/#/R-MMU-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Mus musculus 30616 R-MMU-8983063 https://reactome.org/PathwayBrowser/#/R-MMU-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Mus musculus 30616 R-MMU-8983294 https://reactome.org/PathwayBrowser/#/R-MMU-8983294 Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1 TAS Mus musculus 30616 R-MMU-8983300 https://reactome.org/PathwayBrowser/#/R-MMU-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Mus musculus 30616 R-MMU-8983371 https://reactome.org/PathwayBrowser/#/R-MMU-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Mus musculus 30616 R-MMU-8983834 https://reactome.org/PathwayBrowser/#/R-MMU-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Mus musculus 30616 R-MMU-8983835 https://reactome.org/PathwayBrowser/#/R-MMU-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Mus musculus 30616 R-MMU-8983870 https://reactome.org/PathwayBrowser/#/R-MMU-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Mus musculus 30616 R-MMU-8983872 https://reactome.org/PathwayBrowser/#/R-MMU-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Mus musculus 30616 R-MMU-8984012 https://reactome.org/PathwayBrowser/#/R-MMU-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Mus musculus 30616 R-MMU-8984014 https://reactome.org/PathwayBrowser/#/R-MMU-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Mus musculus 30616 R-MMU-8985914 https://reactome.org/PathwayBrowser/#/R-MMU-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Mus musculus 30616 R-MMU-8985973 https://reactome.org/PathwayBrowser/#/R-MMU-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Mus musculus 30616 R-MMU-8985988 https://reactome.org/PathwayBrowser/#/R-MMU-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Mus musculus 30616 R-MMU-8986985 https://reactome.org/PathwayBrowser/#/R-MMU-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Mus musculus 30616 R-MMU-8986994 https://reactome.org/PathwayBrowser/#/R-MMU-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Mus musculus 30616 R-MMU-8986995 https://reactome.org/PathwayBrowser/#/R-MMU-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Mus musculus 30616 R-MMU-8987012 https://reactome.org/PathwayBrowser/#/R-MMU-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Mus musculus 30616 R-MMU-8987040 https://reactome.org/PathwayBrowser/#/R-MMU-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Mus musculus 30616 R-MMU-8987042 https://reactome.org/PathwayBrowser/#/R-MMU-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Mus musculus 30616 R-MMU-8987070 https://reactome.org/PathwayBrowser/#/R-MMU-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Mus musculus 30616 R-MMU-8987084 https://reactome.org/PathwayBrowser/#/R-MMU-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Mus musculus 30616 R-MMU-8987096 https://reactome.org/PathwayBrowser/#/R-MMU-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Mus musculus 30616 R-MMU-8987129 https://reactome.org/PathwayBrowser/#/R-MMU-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Mus musculus 30616 R-MMU-8987141 https://reactome.org/PathwayBrowser/#/R-MMU-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Mus musculus 30616 R-MMU-8987150 https://reactome.org/PathwayBrowser/#/R-MMU-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Mus musculus 30616 R-MMU-8987179 https://reactome.org/PathwayBrowser/#/R-MMU-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Mus musculus 30616 R-MMU-8987202 https://reactome.org/PathwayBrowser/#/R-MMU-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Mus musculus 30616 R-MMU-8987255 https://reactome.org/PathwayBrowser/#/R-MMU-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Mus musculus 30616 R-MMU-9005848 https://reactome.org/PathwayBrowser/#/R-MMU-9005848 Active Prkaca and CaMK IV phosphorylate Mecp2 at T308 TAS Mus musculus 30616 R-MMU-9005872 https://reactome.org/PathwayBrowser/#/R-MMU-9005872 Active Prkaca, CAMK IV does not phosphorylate Mecp2_e2 mutant R306C at T308 TAS Mus musculus 30616 R-MMU-9006327 https://reactome.org/PathwayBrowser/#/R-MMU-9006327 Phospho-Jak2 phosphorylates Epor TAS Mus musculus 30616 R-MMU-9006329 https://reactome.org/PathwayBrowser/#/R-MMU-9006329 Jak2 transphosphorylates and is activated in response to Erythropoietin TAS Mus musculus 30616 R-MMU-9006466 https://reactome.org/PathwayBrowser/#/R-MMU-9006466 Stat4 is phosphorylated by p-Jak2 and/or p-Y-Tyk2 after Il12:Il12r interaction TAS Mus musculus 30616 R-MMU-9006850 https://reactome.org/PathwayBrowser/#/R-MMU-9006850 IL21 receptor JAK phosphorylation IEA Mus musculus 30616 R-MMU-9006870 https://reactome.org/PathwayBrowser/#/R-MMU-9006870 IL21 receptor STAT phosphorylation IEA Mus musculus 30616 R-MMU-9007015 https://reactome.org/PathwayBrowser/#/R-MMU-9007015 Mecp2 is phosphorylated at S421 TAS Mus musculus 30616 R-MMU-9007137 https://reactome.org/PathwayBrowser/#/R-MMU-9007137 Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1:Grb2:Gab2 phosphorylates Gab2 TAS Mus musculus 30616 R-MMU-9007539 https://reactome.org/PathwayBrowser/#/R-MMU-9007539 CHEK1 phosphorylates E2F6 IEA Mus musculus 30616 R-MMU-9008043 https://reactome.org/PathwayBrowser/#/R-MMU-9008043 MAPK8 phosphorylation IEA Mus musculus 30616 R-MMU-9008412 https://reactome.org/PathwayBrowser/#/R-MMU-9008412 CDK4 phosphorylates RUNX2 IEA Mus musculus 30616 R-MMU-9008684 https://reactome.org/PathwayBrowser/#/R-MMU-9008684 TBK1 phosphorylation IEA Mus musculus 30616 R-MMU-9009072 https://reactome.org/PathwayBrowser/#/R-MMU-9009072 STAT3 phosphorylation IEA Mus musculus 30616 R-MMU-9009282 https://reactome.org/PathwayBrowser/#/R-MMU-9009282 CDK1 phosphorylates RUNX2 IEA Mus musculus 30616 R-MMU-9009867 https://reactome.org/PathwayBrowser/#/R-MMU-9009867 Il2rb and Il2rg are phosphorylated TAS Mus musculus 30616 R-MMU-9009936 https://reactome.org/PathwayBrowser/#/R-MMU-9009936 RNASEL cleaves cellular ssRNA IEA Mus musculus 30616 R-MMU-9009950 https://reactome.org/PathwayBrowser/#/R-MMU-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Mus musculus 30616 R-MMU-9011252 https://reactome.org/PathwayBrowser/#/R-MMU-9011252 Src phosphorylates Robo3.1 in response to Ntn1 TAS Mus musculus 30616 R-MMU-9012268 https://reactome.org/PathwayBrowser/#/R-MMU-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Mus musculus 30616 R-MMU-9012319 https://reactome.org/PathwayBrowser/#/R-MMU-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Mus musculus 30616 R-MMU-9012653 https://reactome.org/PathwayBrowser/#/R-MMU-9012653 Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2 phosphorylates Stat5 TAS Mus musculus 30616 R-MMU-9014741 https://reactome.org/PathwayBrowser/#/R-MMU-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Mus musculus 30616 R-MMU-9014766 https://reactome.org/PathwayBrowser/#/R-MMU-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Mus musculus 30616 R-MMU-9018572 https://reactome.org/PathwayBrowser/#/R-MMU-9018572 EGFR phosphorylates NOTCH3 IEA Mus musculus 30616 R-MMU-9021357 https://reactome.org/PathwayBrowser/#/R-MMU-9021357 PRKCI phosphorylates ELF3 IEA Mus musculus 30616 R-MMU-9021609 https://reactome.org/PathwayBrowser/#/R-MMU-9021609 ESR-associated SRC autophosphorylates IEA Mus musculus 30616 R-MMU-9021627 https://reactome.org/PathwayBrowser/#/R-MMU-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 30616 R-MMU-9022314 https://reactome.org/PathwayBrowser/#/R-MMU-9022314 HIPK2 phosphorylates MECP2 IEA Mus musculus 30616 R-MMU-9023138 https://reactome.org/PathwayBrowser/#/R-MMU-9023138 Aurkb phosphorylates Mecp2 at S421 TAS Mus musculus 30616 R-MMU-9027272 https://reactome.org/PathwayBrowser/#/R-MMU-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Mus musculus 30616 R-MMU-9027273 https://reactome.org/PathwayBrowser/#/R-MMU-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Mus musculus 30616 R-MMU-9027429 https://reactome.org/PathwayBrowser/#/R-MMU-9027429 Lyn phosphorylates Plcg1,2 in Epo:phospho-Epor:phospho-Jak2:Lyn:Irs2:Plcg1,2 TAS Mus musculus 30616 R-MMU-9029147 https://reactome.org/PathwayBrowser/#/R-MMU-9029147 Jak2 phosphorylates Shc1 in Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef:Shc1 TAS Mus musculus 30616 R-MMU-9029162 https://reactome.org/PathwayBrowser/#/R-MMU-9029162 Jak2 phosphorylates Vav1 in Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1:p-Y-Shc1:Grb2-1:Vav1 TAS Mus musculus 30616 R-MMU-9030353 https://reactome.org/PathwayBrowser/#/R-MMU-9030353 Lyn phosphorylates Crkl in Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:Crkl:Rapgef1 TAS Mus musculus 30616 R-MMU-9031553 https://reactome.org/PathwayBrowser/#/R-MMU-9031553 Activated Ntrk2 activates PI3K signaling TAS Mus musculus 30616 R-MMU-9033499 https://reactome.org/PathwayBrowser/#/R-MMU-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Mus musculus 30616 R-MMU-9034714 https://reactome.org/PathwayBrowser/#/R-MMU-9034714 NTRK3 dimers trans-autophosphorylate IEA Mus musculus 30616 R-MMU-9038161 https://reactome.org/PathwayBrowser/#/R-MMU-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Mus musculus 30616 R-MMU-909552 https://reactome.org/PathwayBrowser/#/R-MMU-909552 Phosphorylation of STAT1 at Ser727 IEA Mus musculus 30616 R-MMU-909718 https://reactome.org/PathwayBrowser/#/R-MMU-909718 Formation of p-STAT1 homodimer IEA Mus musculus 30616 R-MMU-909729 https://reactome.org/PathwayBrowser/#/R-MMU-909729 Activation of JAK kinases IEA Mus musculus 30616 R-MMU-909730 https://reactome.org/PathwayBrowser/#/R-MMU-909730 Phosphorylation of INFAR1 by TYK2 IEA Mus musculus 30616 R-MMU-909732 https://reactome.org/PathwayBrowser/#/R-MMU-909732 Phosphorylation of STAT2 IEA Mus musculus 30616 R-MMU-912423 https://reactome.org/PathwayBrowser/#/R-MMU-912423 Atr Phosphorylates Histone H2A.X at Unsynapsed Regions TAS Mus musculus 30616 R-MMU-912527 https://reactome.org/PathwayBrowser/#/R-MMU-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Mus musculus 30616 R-MMU-913996 https://reactome.org/PathwayBrowser/#/R-MMU-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Mus musculus 30616 R-MMU-917693 https://reactome.org/PathwayBrowser/#/R-MMU-917693 ESCRT Disassembly IEA Mus musculus 30616 R-MMU-917841 https://reactome.org/PathwayBrowser/#/R-MMU-917841 Acidification of Tf:TfR1 containing endosome IEA Mus musculus 30616 R-MMU-917979 https://reactome.org/PathwayBrowser/#/R-MMU-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-927889 https://reactome.org/PathwayBrowser/#/R-MMU-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Mus musculus 30616 R-MMU-934559 https://reactome.org/PathwayBrowser/#/R-MMU-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Mus musculus 30616 R-MMU-936802 https://reactome.org/PathwayBrowser/#/R-MMU-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Mus musculus 30616 R-MMU-936883 https://reactome.org/PathwayBrowser/#/R-MMU-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Mus musculus 30616 R-MMU-936895 https://reactome.org/PathwayBrowser/#/R-MMU-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Mus musculus 30616 R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 30616 R-MMU-936951 https://reactome.org/PathwayBrowser/#/R-MMU-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Mus musculus 30616 R-MMU-936991 https://reactome.org/PathwayBrowser/#/R-MMU-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Mus musculus 30616 R-MMU-937034 https://reactome.org/PathwayBrowser/#/R-MMU-937034 IRAK1 phosphorylates Pellino IEA Mus musculus 30616 R-MMU-937311 https://reactome.org/PathwayBrowser/#/R-MMU-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Mus musculus 30616 R-MMU-939763 https://reactome.org/PathwayBrowser/#/R-MMU-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Mus musculus 30616 R-MMU-947531 https://reactome.org/PathwayBrowser/#/R-MMU-947531 Molybdenum ion transfer onto molybdopterin IEA Mus musculus 30616 R-MMU-947591 https://reactome.org/PathwayBrowser/#/R-MMU-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Mus musculus 30616 R-MMU-9603420 https://reactome.org/PathwayBrowser/#/R-MMU-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Mus musculus 30616 R-MMU-9604328 https://reactome.org/PathwayBrowser/#/R-MMU-9604328 AKT1 phosphorylates NOTCH4 IEA Mus musculus 30616 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 30616 R-MMU-9606621 https://reactome.org/PathwayBrowser/#/R-MMU-9606621 Gab2 in Active Flt3:Grb2:Gab2 is phosphorylated TAS Mus musculus 30616 R-MMU-9606884 https://reactome.org/PathwayBrowser/#/R-MMU-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Mus musculus 30616 R-MMU-9607032 https://reactome.org/PathwayBrowser/#/R-MMU-9607032 Lyn, p-Syk phosphorylate Btk TAS Mus musculus 30616 R-MMU-9607033 https://reactome.org/PathwayBrowser/#/R-MMU-9607033 Btk autophosphorylates TAS Mus musculus 30616 R-MMU-9607042 https://reactome.org/PathwayBrowser/#/R-MMU-9607042 Cd19 is phosphorylated TAS Mus musculus 30616 R-MMU-9610153 https://reactome.org/PathwayBrowser/#/R-MMU-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Mus musculus 30616 R-MMU-9610156 https://reactome.org/PathwayBrowser/#/R-MMU-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Mus musculus 30616 R-MMU-9610163 https://reactome.org/PathwayBrowser/#/R-MMU-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Mus musculus 30616 R-MMU-9610641 https://reactome.org/PathwayBrowser/#/R-MMU-9610641 Kif17 transports GluN1:GluN2B (Grin1:Grin2b) NMDA receptors to the plasma membrane TAS Mus musculus 30616 R-MMU-9612501 https://reactome.org/PathwayBrowser/#/R-MMU-9612501 SGK phosphorylates CREB1 IEA Mus musculus 30616 R-MMU-9612509 https://reactome.org/PathwayBrowser/#/R-MMU-9612509 SGK phosphorylates SRF IEA Mus musculus 30616 R-MMU-9613494 https://reactome.org/PathwayBrowser/#/R-MMU-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Mus musculus 30616 R-MMU-9619142 https://reactome.org/PathwayBrowser/#/R-MMU-9619142 Camk4 enters the nucleus TAS Mus musculus 30616 R-MMU-9619355 https://reactome.org/PathwayBrowser/#/R-MMU-9619355 CaMKK autophosphorylates in the cytosol IEA Mus musculus 30616 R-MMU-9624526 https://reactome.org/PathwayBrowser/#/R-MMU-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Mus musculus 30616 R-MMU-9624800 https://reactome.org/PathwayBrowser/#/R-MMU-9624800 CDK1 phosphorylates LBR IEA Mus musculus 30616 R-MMU-9625487 https://reactome.org/PathwayBrowser/#/R-MMU-9625487 PTK2 autophosphorylates downstream of EGFR IEA Mus musculus 30616 R-MMU-9626817 https://reactome.org/PathwayBrowser/#/R-MMU-9626817 PKC phosphorylates NCF1 IEA Mus musculus 30616 R-MMU-9626832 https://reactome.org/PathwayBrowser/#/R-MMU-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Mus musculus 30616 R-MMU-9626880 https://reactome.org/PathwayBrowser/#/R-MMU-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Mus musculus 30616 R-MMU-9627056 https://reactome.org/PathwayBrowser/#/R-MMU-9627056 Procaspase 9 forms dimer IEA Mus musculus 30616 R-MMU-9627089 https://reactome.org/PathwayBrowser/#/R-MMU-9627089 CASP9 is phosphorylated at T412 IEA Mus musculus 30616 R-MMU-9632858 https://reactome.org/PathwayBrowser/#/R-MMU-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Mus musculus 30616 R-MMU-9632868 https://reactome.org/PathwayBrowser/#/R-MMU-9632868 CDKN1B is phosphorylated in response to estrogen IEA Mus musculus 30616 R-MMU-9633504 https://reactome.org/PathwayBrowser/#/R-MMU-9633504 Eif2ak4 phosphorylates Eif2s1 IEA Mus musculus 30616 R-MMU-9633741 https://reactome.org/PathwayBrowser/#/R-MMU-9633741 Eif2ak4 dimer autophosphorylates IEA Mus musculus 30616 R-MMU-9634702 https://reactome.org/PathwayBrowser/#/R-MMU-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Mus musculus 30616 R-MMU-9645136 https://reactome.org/PathwayBrowser/#/R-MMU-9645136 Activator phosphorylates Stat5 TAS Mus musculus 30616 R-MMU-9645442 https://reactome.org/PathwayBrowser/#/R-MMU-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Mus musculus 30616 R-MMU-9645535 https://reactome.org/PathwayBrowser/#/R-MMU-9645535 ALPK1 phosphorylates TIFA IEA Mus musculus 30616 R-MMU-964958 https://reactome.org/PathwayBrowser/#/R-MMU-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Mus musculus 30616 R-MMU-964962 https://reactome.org/PathwayBrowser/#/R-MMU-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Mus musculus 30616 R-MMU-964970 https://reactome.org/PathwayBrowser/#/R-MMU-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Mus musculus 30616 R-MMU-9653503 https://reactome.org/PathwayBrowser/#/R-MMU-9653503 KRAS4B is phosphorylated on serine 181 IEA Mus musculus 30616 R-MMU-9655549 https://reactome.org/PathwayBrowser/#/R-MMU-9655549 p-T-Eif2ak1:ferriheme dimer autophosphorylates TAS Mus musculus 30616 R-MMU-9655565 https://reactome.org/PathwayBrowser/#/R-MMU-9655565 p-T-Eif2ak1 phosphorylates Eif2s1 (eIF2-alpha) TAS Mus musculus 30616 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 30616 R-MMU-9661417 https://reactome.org/PathwayBrowser/#/R-MMU-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-9668419 https://reactome.org/PathwayBrowser/#/R-MMU-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Mus musculus 30616 R-MMU-9668464 https://reactome.org/PathwayBrowser/#/R-MMU-9668464 Atp2b2 (PMCA2) transports Ca2+ from the cytosol to the extracellular region TAS Mus musculus 30616 R-MMU-9674900 https://reactome.org/PathwayBrowser/#/R-MMU-9674900 Csf3:Csf3r induces phosphorylation of Jak1 TAS Mus musculus 30616 R-MMU-9674908 https://reactome.org/PathwayBrowser/#/R-MMU-9674908 p-Y-Jak1,2 phosphorylates Stat1,3,5 in Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2:Stat1,3,5 TAS Mus musculus 30616 R-MMU-9674921 https://reactome.org/PathwayBrowser/#/R-MMU-9674921 p-Y-Jak1 phosphorylates Csf3r in Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2 TAS Mus musculus 30616 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 30616 R-MMU-9680646 https://reactome.org/PathwayBrowser/#/R-MMU-9680646 Pik3r11:Pik3ca,b,d (Pi3k), Plcg2 (PLCgamma2), Grb2:Sos1, Shc1 (Shc), Ptpn11 (Shp2), Grb2:Gab2, Grb2:Gab3, Grap2 (MONA), Cbl:Grb2, Inpp5d (SHIP1), Inppl1 (SHIP2) bind p-8Y-Csf1r and are activated TAS Mus musculus 30616 R-MMU-9680706 https://reactome.org/PathwayBrowser/#/R-MMU-9680706 Csf1r trans-autophosphorylates on multiple tyrosine residues TAS Mus musculus 30616 R-MMU-9682182 https://reactome.org/PathwayBrowser/#/R-MMU-9682182 Csf1r-associated PI3K phosphorylates phosphatidylinositol 4,5-bisphosphate TAS Mus musculus 30616 R-MMU-9684118 https://reactome.org/PathwayBrowser/#/R-MMU-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Mus musculus 30616 R-MMU-9686521 https://reactome.org/PathwayBrowser/#/R-MMU-9686521 CDK2:CCNA phosphorylates TERF2 IEA Mus musculus 30616 R-MMU-9687625 https://reactome.org/PathwayBrowser/#/R-MMU-9687625 ATP binds MLKL IEA Mus musculus 30616 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 30616 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 30616 R-MMU-9699578 https://reactome.org/PathwayBrowser/#/R-MMU-9699578 Active FLT3 phosphorylates CDKN1B IEA Mus musculus 30616 R-MMU-9699579 https://reactome.org/PathwayBrowser/#/R-MMU-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Mus musculus 30616 R-MMU-9700168 https://reactome.org/PathwayBrowser/#/R-MMU-9700168 Active ALK phosphorylates IRS1 IEA Mus musculus 30616 R-MMU-9700171 https://reactome.org/PathwayBrowser/#/R-MMU-9700171 Active ALK phosphorylates PLCG1 IEA Mus musculus 30616 R-MMU-9700175 https://reactome.org/PathwayBrowser/#/R-MMU-9700175 Active ALK phosphorylates SHC1 IEA Mus musculus 30616 R-MMU-9701488 https://reactome.org/PathwayBrowser/#/R-MMU-9701488 Active ALK phosphorylates JAK3 IEA Mus musculus 30616 R-MMU-9705925 https://reactome.org/PathwayBrowser/#/R-MMU-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Mus musculus 30616 R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 30616 R-MMU-9706344 https://reactome.org/PathwayBrowser/#/R-MMU-9706344 FLT3 phosphorylates GRB10 IEA Mus musculus 30616 R-MMU-9706350 https://reactome.org/PathwayBrowser/#/R-MMU-9706350 FLT3 phosphorylates CBL IEA Mus musculus 30616 R-MMU-9706390 https://reactome.org/PathwayBrowser/#/R-MMU-9706390 RHOBTB3 binds interacting proteins at trans-Golgi network IEA Mus musculus 30616 R-MMU-9706393 https://reactome.org/PathwayBrowser/#/R-MMU-9706393 RHOBTB3 binds ATP IEA Mus musculus 30616 R-MMU-9706399 https://reactome.org/PathwayBrowser/#/R-MMU-9706399 RHOBTB3 hydrolyzes ATP IEA Mus musculus 30616 R-MMU-9706837 https://reactome.org/PathwayBrowser/#/R-MMU-9706837 AR binds AR antagonists IEA Mus musculus 30616 R-MMU-9709373 https://reactome.org/PathwayBrowser/#/R-MMU-9709373 Ptk6 phosphorylates Stat3 TAS Mus musculus 30616 R-MMU-9709547 https://reactome.org/PathwayBrowser/#/R-MMU-9709547 ESTG binds ESR2:chaperone complex IEA Mus musculus 30616 R-MMU-9713712 https://reactome.org/PathwayBrowser/#/R-MMU-9713712 Adcy3:Gnal:GTP converts ATP to cAMP TAS Mus musculus 30616 R-MMU-9716913 https://reactome.org/PathwayBrowser/#/R-MMU-9716913 ESR1 binds ESR1 antagonists IEA Mus musculus 30616 R-MMU-9716947 https://reactome.org/PathwayBrowser/#/R-MMU-9716947 ESR1 binds ESR1 agonists IEA Mus musculus 30616 R-MMU-9717434 https://reactome.org/PathwayBrowser/#/R-MMU-9717434 Calhm1:Calhm3 transports ATP from the cytosol to the extracellular region TAS Mus musculus 30616 R-MMU-9725855 https://reactome.org/PathwayBrowser/#/R-MMU-9725855 NR3C2 binds NR3C2 antagonists IEA Mus musculus 30616 R-MMU-9725885 https://reactome.org/PathwayBrowser/#/R-MMU-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Mus musculus 30616 R-MMU-9726509 https://reactome.org/PathwayBrowser/#/R-MMU-9726509 NR3C2 binds fludrocortisone IEA Mus musculus 30616 R-MMU-9726580 https://reactome.org/PathwayBrowser/#/R-MMU-9726580 PGR binds PGR agonists IEA Mus musculus 30616 R-MMU-9726621 https://reactome.org/PathwayBrowser/#/R-MMU-9726621 PGR binds PGR antagonists IEA Mus musculus 30616 R-MMU-9727198 https://reactome.org/PathwayBrowser/#/R-MMU-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Mus musculus 30616 R-MMU-9731111 https://reactome.org/PathwayBrowser/#/R-MMU-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Mus musculus 30616 R-MMU-9732738 https://reactome.org/PathwayBrowser/#/R-MMU-9732738 JAK1-mediated phosphorylation of RAF1 IEA Mus musculus 30616 R-MMU-9732753 https://reactome.org/PathwayBrowser/#/R-MMU-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Mus musculus 30616 R-MMU-9734535 https://reactome.org/PathwayBrowser/#/R-MMU-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Mus musculus 30616 R-MMU-9734547 https://reactome.org/PathwayBrowser/#/R-MMU-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Mus musculus 30616 R-MMU-9734687 https://reactome.org/PathwayBrowser/#/R-MMU-9734687 ORC6 is phosphorylated on T195 IEA Mus musculus 30616 R-MMU-9748949 https://reactome.org/PathwayBrowser/#/R-MMU-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Mus musculus 30616 R-MMU-9748957 https://reactome.org/PathwayBrowser/#/R-MMU-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Mus musculus 30616 R-MMU-9748963 https://reactome.org/PathwayBrowser/#/R-MMU-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Mus musculus 30616 R-MMU-9748969 https://reactome.org/PathwayBrowser/#/R-MMU-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Mus musculus 30616 R-MMU-9748999 https://reactome.org/PathwayBrowser/#/R-MMU-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Mus musculus 30616 R-MMU-9749971 https://reactome.org/PathwayBrowser/#/R-MMU-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Mus musculus 30616 R-MMU-9750546 https://reactome.org/PathwayBrowser/#/R-MMU-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-9750617 https://reactome.org/PathwayBrowser/#/R-MMU-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-9750656 https://reactome.org/PathwayBrowser/#/R-MMU-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Mus musculus 30616 R-MMU-975103 https://reactome.org/PathwayBrowser/#/R-MMU-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Mus musculus 30616 R-MMU-975139 https://reactome.org/PathwayBrowser/#/R-MMU-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Mus musculus 30616 R-MMU-9753278 https://reactome.org/PathwayBrowser/#/R-MMU-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 30616 R-MMU-9753283 https://reactome.org/PathwayBrowser/#/R-MMU-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 30616 R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 30616 R-MMU-9754974 https://reactome.org/PathwayBrowser/#/R-MMU-9754974 ADK phosphorylates RBV IEA Mus musculus 30616 R-MMU-9755013 https://reactome.org/PathwayBrowser/#/R-MMU-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Mus musculus 30616 R-MMU-9759206 https://reactome.org/PathwayBrowser/#/R-MMU-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Mus musculus 30616 R-MMU-9759454 https://reactome.org/PathwayBrowser/#/R-MMU-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Mus musculus 30616 R-MMU-9759461 https://reactome.org/PathwayBrowser/#/R-MMU-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Mus musculus 30616 R-MMU-9760094 https://reactome.org/PathwayBrowser/#/R-MMU-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Mus musculus 30616 R-MMU-9762094 https://reactome.org/PathwayBrowser/#/R-MMU-9762094 GSK3B phosphorylates p-NFE2L2 IEA Mus musculus 30616 R-MMU-9763891 https://reactome.org/PathwayBrowser/#/R-MMU-9763891 Src family kinases phosphorylate Cbl in Csf1 dimer:p-Y559-Csf1r dimer:Cbl TAS Mus musculus 30616 R-MMU-9763901 https://reactome.org/PathwayBrowser/#/R-MMU-9763901 Csf1r trans-autophosphoryates on tyrosine-559 TAS Mus musculus 30616 R-MMU-9769840 https://reactome.org/PathwayBrowser/#/R-MMU-9769840 Mapk1,(Mapk3) phosphorylate Npas4 TAS Mus musculus 30616 R-MMU-9770141 https://reactome.org/PathwayBrowser/#/R-MMU-9770141 Formation of the Spliceosomal C* complex IEA Mus musculus 30616 R-MMU-9770142 https://reactome.org/PathwayBrowser/#/R-MMU-9770142 Formation of the Spliceosomal B complex IEA Mus musculus 30616 R-MMU-9770145 https://reactome.org/PathwayBrowser/#/R-MMU-9770145 Formation of the Spliceosomal Bact complex IEA Mus musculus 30616 R-MMU-9773803 https://reactome.org/PathwayBrowser/#/R-MMU-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Mus musculus 30616 R-MMU-9794120 https://reactome.org/PathwayBrowser/#/R-MMU-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Mus musculus 30616 R-MMU-9794572 https://reactome.org/PathwayBrowser/#/R-MMU-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Mus musculus 30616 R-MMU-9796053 https://reactome.org/PathwayBrowser/#/R-MMU-9796053 PRKCI phosphorylates NFE2L2 IEA Mus musculus 30616 R-MMU-9796067 https://reactome.org/PathwayBrowser/#/R-MMU-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Mus musculus 30616 R-MMU-9815501 https://reactome.org/PathwayBrowser/#/R-MMU-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 IEA Mus musculus 30616 R-MMU-9817397 https://reactome.org/PathwayBrowser/#/R-MMU-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Mus musculus 30616 R-MMU-9818776 https://reactome.org/PathwayBrowser/#/R-MMU-9818776 Eif2ak3 phosphorylates Nfe2l2 TAS Mus musculus 30616 R-MMU-9818789 https://reactome.org/PathwayBrowser/#/R-MMU-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Mus musculus 30616 R-MMU-9819106 https://reactome.org/PathwayBrowser/#/R-MMU-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Mus musculus 30616 R-MMU-9821987 https://reactome.org/PathwayBrowser/#/R-MMU-9821987 Srpk1 phosphorylates Prm2 in Prm2:dsDNA TAS Mus musculus 30616 R-MMU-9821990 https://reactome.org/PathwayBrowser/#/R-MMU-9821990 Srpk1 phosphorylates Prm1 in Prm1:dsDNA TAS Mus musculus 30616 R-MMU-9823906 https://reactome.org/PathwayBrowser/#/R-MMU-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Mus musculus 30616 R-MMU-9824882 https://reactome.org/PathwayBrowser/#/R-MMU-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Mus musculus 30616 R-MMU-9824977 https://reactome.org/PathwayBrowser/#/R-MMU-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Mus musculus 30616 R-MMU-9824994 https://reactome.org/PathwayBrowser/#/R-MMU-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Mus musculus 30616 R-MMU-9824995 https://reactome.org/PathwayBrowser/#/R-MMU-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Mus musculus 30616 R-MMU-9824999 https://reactome.org/PathwayBrowser/#/R-MMU-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Mus musculus 30616 R-MMU-9825759 https://reactome.org/PathwayBrowser/#/R-MMU-9825759 MAPK-dependent phosphorylation of KARS IEA Mus musculus 30616 R-MMU-982807 https://reactome.org/PathwayBrowser/#/R-MMU-982807 JAK2 phosphorylation of GHR IEA Mus musculus 30616 R-MMU-982810 https://reactome.org/PathwayBrowser/#/R-MMU-982810 JAK2 phosphorylation IEA Mus musculus 30616 R-MMU-983140 https://reactome.org/PathwayBrowser/#/R-MMU-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Mus musculus 30616 R-MMU-983144 https://reactome.org/PathwayBrowser/#/R-MMU-983144 Transport of Antigen peptide in to ER IEA Mus musculus 30616 R-MMU-983153 https://reactome.org/PathwayBrowser/#/R-MMU-983153 E1 mediated ubiquitin activation IEA Mus musculus 30616 R-MMU-983156 https://reactome.org/PathwayBrowser/#/R-MMU-983156 Polyubiquitination of substrate IEA Mus musculus 30616 R-MMU-983259 https://reactome.org/PathwayBrowser/#/R-MMU-983259 Kinesins move along microtubules consuming ATP IEA Mus musculus 30616 R-MMU-9833973 https://reactome.org/PathwayBrowser/#/R-MMU-9833973 ISGylation of PKR IEA Mus musculus 30616 R-MMU-9836159 https://reactome.org/PathwayBrowser/#/R-MMU-9836159 p-PKR dimer phosphorylates DHX9 IEA Mus musculus 30616 R-MMU-9836184 https://reactome.org/PathwayBrowser/#/R-MMU-9836184 p-PKR dimer phosphorylates CDK1 IEA Mus musculus 30616 R-MMU-9836322 https://reactome.org/PathwayBrowser/#/R-MMU-9836322 p-PKR dimer phosphorylates MKK6 IEA Mus musculus 30616 R-MMU-9836362 https://reactome.org/PathwayBrowser/#/R-MMU-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Mus musculus 30616 R-MMU-9836383 https://reactome.org/PathwayBrowser/#/R-MMU-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Mus musculus 30616 R-MMU-9836404 https://reactome.org/PathwayBrowser/#/R-MMU-9836404 p-PKR dimer phosphorylates MAPT IEA Mus musculus 30616 R-MMU-9836435 https://reactome.org/PathwayBrowser/#/R-MMU-9836435 p-PKR dimer phosphorylates SNCA IEA Mus musculus 30616 R-MMU-9836515 https://reactome.org/PathwayBrowser/#/R-MMU-9836515 p-PKR dimer phosphorylates PTPN2 IEA Mus musculus 30616 R-MMU-9836617 https://reactome.org/PathwayBrowser/#/R-MMU-9836617 p-PKR dimer phosphorylates SPHK1 IEA Mus musculus 30616 R-MMU-9836664 https://reactome.org/PathwayBrowser/#/R-MMU-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Mus musculus 30616 R-MMU-983702 https://reactome.org/PathwayBrowser/#/R-MMU-983702 Phosphorylation of ITAMs of Ig-alpha (Cd79a) and Ig-beta (Cd79b) TAS Mus musculus 30616 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus 30616 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus 30616 R-MMU-9837337 https://reactome.org/PathwayBrowser/#/R-MMU-9837337 DCAKD phosphorylates DP-CoA IEA Mus musculus 30616 R-MMU-9838004 https://reactome.org/PathwayBrowser/#/R-MMU-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Mus musculus 30616 R-MMU-9838081 https://reactome.org/PathwayBrowser/#/R-MMU-9838081 LONP1 degrades mitochondrial matrix proteins IEA Mus musculus 30616 R-MMU-9838289 https://reactome.org/PathwayBrowser/#/R-MMU-9838289 CLPXP degrades mitochondrial matrix proteins IEA Mus musculus 30616 R-MMU-9838321 https://reactome.org/PathwayBrowser/#/R-MMU-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Mus musculus 30616 R-MMU-9839059 https://reactome.org/PathwayBrowser/#/R-MMU-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Mus musculus 30616 R-MMU-9839105 https://reactome.org/PathwayBrowser/#/R-MMU-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Mus musculus 30616 R-MMU-9839113 https://reactome.org/PathwayBrowser/#/R-MMU-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Mus musculus 30616 R-MMU-9840564 https://reactome.org/PathwayBrowser/#/R-MMU-9840564 OMA1 hydrolyzes YME1L1 IEA Mus musculus 30616 R-MMU-9842648 https://reactome.org/PathwayBrowser/#/R-MMU-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 IEA Mus musculus 30616 R-MMU-9842651 https://reactome.org/PathwayBrowser/#/R-MMU-9842651 Active LTK receptor phosphorylates SHC1 IEA Mus musculus 30616 R-MMU-9842666 https://reactome.org/PathwayBrowser/#/R-MMU-9842666 Active LTK phosphorylates IRS1 IEA Mus musculus 30616 R-MMU-9843721 https://reactome.org/PathwayBrowser/#/R-MMU-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Mus musculus 30616 R-MMU-9851972 https://reactome.org/PathwayBrowser/#/R-MMU-9851972 PLK1 phosphorylates FIRRM at S43 IEA Mus musculus 30616 R-MMU-9853369 https://reactome.org/PathwayBrowser/#/R-MMU-9853369 PLK1 phosphorylates FIRMM at S744 IEA Mus musculus 30616 R-MMU-9861642 https://reactome.org/PathwayBrowser/#/R-MMU-9861642 NEK1 phosphorylates ME1 IEA Mus musculus 30616 R-MMU-994137 https://reactome.org/PathwayBrowser/#/R-MMU-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Mus musculus 30616 R-MMU-994140 https://reactome.org/PathwayBrowser/#/R-MMU-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Mus musculus 30616 R-MTU-879319 https://reactome.org/PathwayBrowser/#/R-MTU-879319 glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol TAS Mycobacterium tuberculosis 30616 R-MTU-936583 https://reactome.org/PathwayBrowser/#/R-MTU-936583 APS is phosphorylated to PAPS TAS Mycobacterium tuberculosis 30616 R-MTU-936631 https://reactome.org/PathwayBrowser/#/R-MTU-936631 sulfate uptake in the cytosol TAS Mycobacterium tuberculosis 30616 R-MTU-936729 https://reactome.org/PathwayBrowser/#/R-MTU-936729 sulfate is activated to APS TAS Mycobacterium tuberculosis 30616 R-MTU-9635480 https://reactome.org/PathwayBrowser/#/R-MTU-9635480 FadD26, FadD28 transfer adenylyl group to a LCFA TAS Mycobacterium tuberculosis 30616 R-MTU-964939 https://reactome.org/PathwayBrowser/#/R-MTU-964939 Phosphorylation of shikimate TAS Mycobacterium tuberculosis 30616 R-NUL-1181349 https://reactome.org/PathwayBrowser/#/R-NUL-1181349 Phosphorylation of Smad2 by Nodal Receptor TAS Homo sapiens 30616 R-NUL-1236944 https://reactome.org/PathwayBrowser/#/R-NUL-1236944 Translocation of antigenic peptides back to phagosomes via TAP TAS Gallus gallus 30616 R-NUL-1251929 https://reactome.org/PathwayBrowser/#/R-NUL-1251929 Plcg1 phosphorylation by P-ERBB2:P-EGFR TAS Homo sapiens 30616 R-NUL-1458902 https://reactome.org/PathwayBrowser/#/R-NUL-1458902 frog CK1gamma phosphorylates LRP5/6 TAS Homo sapiens 30616 R-NUL-1675886 https://reactome.org/PathwayBrowser/#/R-NUL-1675886 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the early endosome membrane TAS Mus musculus 30616 R-NUL-1675925 https://reactome.org/PathwayBrowser/#/R-NUL-1675925 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the late endosome membrane TAS Mus musculus 30616 R-NUL-1675982 https://reactome.org/PathwayBrowser/#/R-NUL-1675982 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the Golgi membrane TAS Mus musculus 30616 R-NUL-1676051 https://reactome.org/PathwayBrowser/#/R-NUL-1676051 PI is phosphorylated to PI5P by Pikfyve at the late endosome membrane TAS Mus musculus 30616 R-NUL-2065178 https://reactome.org/PathwayBrowser/#/R-NUL-2065178 CDK8 phosphorylates xNICD1 TAS Homo sapiens 30616 R-NUL-209060 https://reactome.org/PathwayBrowser/#/R-NUL-209060 Human APC is further phosphorylated by Murine GSK3beta TAS Homo sapiens 30616 R-NUL-209065 https://reactome.org/PathwayBrowser/#/R-NUL-209065 Human APC is further phosphorylated by Murine CKIepsilon TAS Homo sapiens 30616 R-NUL-209104 https://reactome.org/PathwayBrowser/#/R-NUL-209104 Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex TAS Homo sapiens 30616 R-NUL-209132 https://reactome.org/PathwayBrowser/#/R-NUL-209132 Human APC is initially phosphorylated by Murine CKIepsilon TAS Homo sapiens 30616 R-NUL-209144 https://reactome.org/PathwayBrowser/#/R-NUL-209144 Human APC is finally phosphorylated by Murine GSK3beta TAS Homo sapiens 30616 R-NUL-209146 https://reactome.org/PathwayBrowser/#/R-NUL-209146 Murine Axin1 is further phosphorylated by Human GSK3beta TAS Mus musculus 30616 R-NUL-2161165 https://reactome.org/PathwayBrowser/#/R-NUL-2161165 TGFBR2 phosphorylates Pard6a TAS Homo sapiens 30616 R-NUL-2422970 https://reactome.org/PathwayBrowser/#/R-NUL-2422970 Phosphorylation of Gorasp1, Golga2 and RAB1A by CDK1:CCNB TAS Homo sapiens 30616 R-NUL-2434198 https://reactome.org/PathwayBrowser/#/R-NUL-2434198 CDK1 phosphorylates Mastl TAS Homo sapiens 30616 R-NUL-3139045 https://reactome.org/PathwayBrowser/#/R-NUL-3139045 AKT phosphorylates Bad TAS Homo sapiens 30616 R-NUL-3245934 https://reactome.org/PathwayBrowser/#/R-NUL-3245934 Mapk1 (Erk2) phosphorylates ERF TAS Homo sapiens 30616 R-NUL-3299417 https://reactome.org/PathwayBrowser/#/R-NUL-3299417 MAP3K5 (ASK1) phosphorylates Map2k4(Sek1) TAS Homo sapiens 30616 R-NUL-3858478 https://reactome.org/PathwayBrowser/#/R-NUL-3858478 Rat Dvl is phosophorylated upon Wnt binding TAS Mus musculus 30616 R-NUL-3876071 https://reactome.org/PathwayBrowser/#/R-NUL-3876071 RPS6KA1/2/3 phosphorylates Cebpb on S273 TAS Homo sapiens 30616 R-NUL-389973 https://reactome.org/PathwayBrowser/#/R-NUL-389973 ADP is exchanged for ATP in the ADP:CCT/TriC:tubulin complex TAS Mus musculus 30616 R-NUL-391408 https://reactome.org/PathwayBrowser/#/R-NUL-391408 Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC TAS Mus musculus 30616 R-NUL-391434 https://reactome.org/PathwayBrowser/#/R-NUL-391434 Exchange of ADP for ATP in CCT/TriC:actin complex TAS Bos taurus 30616 R-NUL-391437 https://reactome.org/PathwayBrowser/#/R-NUL-391437 Hydrolysis of ATP and release of folded actin from CCT/TriC TAS Bos taurus 30616 R-NUL-420398 https://reactome.org/PathwayBrowser/#/R-NUL-420398 Autophosphorylation of NCAM1 bound Fyn TAS Mus musculus 30616 R-NUL-421062 https://reactome.org/PathwayBrowser/#/R-NUL-421062 Myosin phosphatase inactivation by ROCK2 TAS Bos taurus 30616 R-NUL-421136 https://reactome.org/PathwayBrowser/#/R-NUL-421136 Recruitment and activation of Cdk5 TAS Gallus gallus 30616 R-NUL-421139 https://reactome.org/PathwayBrowser/#/R-NUL-421139 Limk1 phosphorylates Cfl1, inactivating it TAS Homo sapiens 30616 R-NUL-421724 https://reactome.org/PathwayBrowser/#/R-NUL-421724 Myosin regulatory light chain phosphorylation by Rock2 TAS Gallus gallus 30616 R-NUL-421733 https://reactome.org/PathwayBrowser/#/R-NUL-421733 ROCK1 phosphorylates LIMK2 (rat) TAS Homo sapiens 30616 R-NUL-437938 https://reactome.org/PathwayBrowser/#/R-NUL-437938 Syk phosphorylates VAV1 TAS Homo sapiens 30616 R-NUL-445066 https://reactome.org/PathwayBrowser/#/R-NUL-445066 Phosphorylation of L1 by p90rsk TAS Homo sapiens 30616 R-NUL-451681 https://reactome.org/PathwayBrowser/#/R-NUL-451681 Tpl2 phosphorylates Mek1, Sek1 TAS Mus musculus 30616 R-NUL-5610714 https://reactome.org/PathwayBrowser/#/R-NUL-5610714 GSK3 phosphorylates p-Gli2 TAS Mus musculus 30616 R-NUL-5610715 https://reactome.org/PathwayBrowser/#/R-NUL-5610715 CK1 phosphorylates p-Gli2 TAS Mus musculus 30616 R-NUL-5610740 https://reactome.org/PathwayBrowser/#/R-NUL-5610740 Pka phosphorylates GLI1 TAS Mus musculus 30616 R-NUL-5671959 https://reactome.org/PathwayBrowser/#/R-NUL-5671959 Activated Cit phosphorylates MRLCs of myosin II complex TAS Bos taurus 30616 R-NUL-804924 https://reactome.org/PathwayBrowser/#/R-NUL-804924 PKC (cow) phosphorylates G alpha z (rat) TAS Bos taurus 30616 R-NUL-8870566 https://reactome.org/PathwayBrowser/#/R-NUL-8870566 Cdk5:p25 phosphorylates FOXO3 TAS Homo sapiens 30616 R-NUL-8939977 https://reactome.org/PathwayBrowser/#/R-NUL-8939977 Activated AKT1 phosphorylates Runx2 TAS Homo sapiens 30616 R-NUL-8955873 https://reactome.org/PathwayBrowser/#/R-NUL-8955873 Polyglutamylase complex (Ttll1) polyglutamylates alpha subunits of tubulin TAS Homo sapiens 30616 R-NUL-9008636 https://reactome.org/PathwayBrowser/#/R-NUL-9008636 GSK3B phosphorylates Runx2 TAS Homo sapiens 30616 R-NUL-9009236 https://reactome.org/PathwayBrowser/#/R-NUL-9009236 Activated ERKs phosphorylate Runx2 TAS Homo sapiens 30616 R-NUL-9030372 https://reactome.org/PathwayBrowser/#/R-NUL-9030372 BDNF-bound Ntrk2 dimers trans-autophosphorylate TAS Homo sapiens 30616 R-NUL-9030397 https://reactome.org/PathwayBrowser/#/R-NUL-9030397 NTF3-bound Ntrk2 dimers trans-autophosphorylate TAS Homo sapiens 30616 R-NUL-9030427 https://reactome.org/PathwayBrowser/#/R-NUL-9030427 NTF4-bound Ntrk2 dimers trans-autophosphorylate TAS Homo sapiens 30616 R-NUL-9030450 https://reactome.org/PathwayBrowser/#/R-NUL-9030450 BDNF- or NTF4-activated Ntrk2 phosphorylates Plcg1 TAS Homo sapiens 30616 R-NUL-9031971 https://reactome.org/PathwayBrowser/#/R-NUL-9031971 Ntrk2 phosphorylates Frs2 TAS Homo sapiens 30616 R-NUL-9032423 https://reactome.org/PathwayBrowser/#/R-NUL-9032423 Ntrk2 phosphorylates FRS3 TAS Homo sapiens 30616 R-NUL-9032945 https://reactome.org/PathwayBrowser/#/R-NUL-9032945 Ntrk2 phosohorylates CDK5 TAS Homo sapiens 30616 R-NUL-9032961 https://reactome.org/PathwayBrowser/#/R-NUL-9032961 Cdk5 phosphorylates Ntrk2 TAS Homo sapiens 30616 R-NUL-9033333 https://reactome.org/PathwayBrowser/#/R-NUL-9033333 Ntrk2 promotes Tiam1 phosphorylation TAS Homo sapiens 30616 R-NUL-9034815 https://reactome.org/PathwayBrowser/#/R-NUL-9034815 Ntrk3 phosphorylates Plcg1 TAS Homo sapiens 30616 R-NUL-9036937 https://reactome.org/PathwayBrowser/#/R-NUL-9036937 Ntrk3 phosphorylates Shc1 TAS Homo sapiens 30616 R-NUL-9615367 https://reactome.org/PathwayBrowser/#/R-NUL-9615367 Prkaca phosphorylates Creb1 TAS Rattus norvegicus 30616 R-NUL-9616944 https://reactome.org/PathwayBrowser/#/R-NUL-9616944 Activated Ntrk3 stimulates PI3K activity TAS Mus musculus 30616 R-NUL-9619177 https://reactome.org/PathwayBrowser/#/R-NUL-9619177 Camkk2 phosphorylates CAMK4 TAS Homo sapiens 30616 R-NUL-9619396 https://reactome.org/PathwayBrowser/#/R-NUL-9619396 CAMKK1 phosphorylates CAMK1 TAS Homo sapiens 30616 R-NUL-9619413 https://reactome.org/PathwayBrowser/#/R-NUL-9619413 CAMKK2 phosphorylates Camk1 TAS Homo sapiens 30616 R-NUL-9619488 https://reactome.org/PathwayBrowser/#/R-NUL-9619488 Camkk2 phosphorylates AMPK TAS Rattus norvegicus 30616 R-NUL-9619534 https://reactome.org/PathwayBrowser/#/R-NUL-9619534 AMPK phosphorylates Mapt TAS Rattus norvegicus 30616 R-NUL-9619973 https://reactome.org/PathwayBrowser/#/R-NUL-9619973 MAPK1 phosphorylates Rps6ka1 TAS Homo sapiens 30616 R-NUL-9620024 https://reactome.org/PathwayBrowser/#/R-NUL-9620024 PDPK1 phosphorylates Rps6ka2 TAS Homo sapiens 30616 R-NUL-9700161 https://reactome.org/PathwayBrowser/#/R-NUL-9700161 p-7Y ALK dimer phosphorylates Frs2 TAS Homo sapiens 30616 R-NUL-9700655 https://reactome.org/PathwayBrowser/#/R-NUL-9700655 Active ALK phosphorylates Src TAS Homo sapiens 30616 R-NUL-9726861 https://reactome.org/PathwayBrowser/#/R-NUL-9726861 Src phosphorylates RHOU TAS Homo sapiens 30616 R-NUL-994158 https://reactome.org/PathwayBrowser/#/R-NUL-994158 F-actin capping protein binds to elongating F-actin TAS Gallus gallus 30616 R-OCU-211638 https://reactome.org/PathwayBrowser/#/R-OCU-211638 Autophosphorylation of PAK-2p34 TAS Oryctolagus cuniculus 30616 R-OCU-213297 https://reactome.org/PathwayBrowser/#/R-OCU-213297 Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197 TAS Oryctolagus cuniculus 30616 R-OCU-9655594 https://reactome.org/PathwayBrowser/#/R-OCU-9655594 p-T-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) TAS Oryctolagus cuniculus 30616 R-PCH-2408503 https://reactome.org/PathwayBrowser/#/R-PCH-2408503 APSe is phosphorylated to PAPSe by Kaps TAS Penicillium chrysogenum 30616 R-PFA-110133 https://reactome.org/PathwayBrowser/#/R-PFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Plasmodium falciparum 30616 R-PFA-110137 https://reactome.org/PathwayBrowser/#/R-PFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Plasmodium falciparum 30616 R-PFA-110138 https://reactome.org/PathwayBrowser/#/R-PFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 30616 R-PFA-110144 https://reactome.org/PathwayBrowser/#/R-PFA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Plasmodium falciparum 30616 R-PFA-110145 https://reactome.org/PathwayBrowser/#/R-PFA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Plasmodium falciparum 30616 R-PFA-111742 https://reactome.org/PathwayBrowser/#/R-PFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 30616 R-PFA-111751 https://reactome.org/PathwayBrowser/#/R-PFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 30616 R-PFA-111804 https://reactome.org/PathwayBrowser/#/R-PFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 30616 R-PFA-111915 https://reactome.org/PathwayBrowser/#/R-PFA-111915 CAMK4 autophosphorylates IEA Plasmodium falciparum 30616 R-PFA-1169397 https://reactome.org/PathwayBrowser/#/R-PFA-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Plasmodium falciparum 30616 R-PFA-1369028 https://reactome.org/PathwayBrowser/#/R-PFA-1369028 ABCAs mediate lipid efflux IEA Plasmodium falciparum 30616 R-PFA-1369052 https://reactome.org/PathwayBrowser/#/R-PFA-1369052 ABCAs mediate lipid influx IEA Plasmodium falciparum 30616 R-PFA-1369065 https://reactome.org/PathwayBrowser/#/R-PFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Plasmodium falciparum 30616 R-PFA-1454916 https://reactome.org/PathwayBrowser/#/R-PFA-1454916 The ABCC family mediates organic anion transport IEA Plasmodium falciparum 30616 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 30616 R-PFA-1467466 https://reactome.org/PathwayBrowser/#/R-PFA-1467466 ABCA4 mediates atRAL transport IEA Plasmodium falciparum 30616 R-PFA-1483004 https://reactome.org/PathwayBrowser/#/R-PFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Plasmodium falciparum 30616 R-PFA-1483222 https://reactome.org/PathwayBrowser/#/R-PFA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Plasmodium falciparum 30616 R-PFA-156682 https://reactome.org/PathwayBrowser/#/R-PFA-156682 PLK1 phosphorylates NUDC IEA Plasmodium falciparum 30616 R-PFA-163215 https://reactome.org/PathwayBrowser/#/R-PFA-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Plasmodium falciparum 30616 R-PFA-1675773 https://reactome.org/PathwayBrowser/#/R-PFA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Plasmodium falciparum 30616 R-PFA-1675776 https://reactome.org/PathwayBrowser/#/R-PFA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Plasmodium falciparum 30616 R-PFA-1675810 https://reactome.org/PathwayBrowser/#/R-PFA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Plasmodium falciparum 30616 R-PFA-1675883 https://reactome.org/PathwayBrowser/#/R-PFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Plasmodium falciparum 30616 R-PFA-1675939 https://reactome.org/PathwayBrowser/#/R-PFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Plasmodium falciparum 30616 R-PFA-1675961 https://reactome.org/PathwayBrowser/#/R-PFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Plasmodium falciparum 30616 R-PFA-1676024 https://reactome.org/PathwayBrowser/#/R-PFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Plasmodium falciparum 30616 R-PFA-1676082 https://reactome.org/PathwayBrowser/#/R-PFA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Plasmodium falciparum 30616 R-PFA-1676134 https://reactome.org/PathwayBrowser/#/R-PFA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Plasmodium falciparum 30616 R-PFA-1676145 https://reactome.org/PathwayBrowser/#/R-PFA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Plasmodium falciparum 30616 R-PFA-174391 https://reactome.org/PathwayBrowser/#/R-PFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Plasmodium falciparum 30616 R-PFA-174394 https://reactome.org/PathwayBrowser/#/R-PFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Plasmodium falciparum 30616 R-PFA-1855153 https://reactome.org/PathwayBrowser/#/R-PFA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Plasmodium falciparum 30616 R-PFA-1855157 https://reactome.org/PathwayBrowser/#/R-PFA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 30616 R-PFA-1855158 https://reactome.org/PathwayBrowser/#/R-PFA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 30616 R-PFA-1855181 https://reactome.org/PathwayBrowser/#/R-PFA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 30616 R-PFA-1855182 https://reactome.org/PathwayBrowser/#/R-PFA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Plasmodium falciparum 30616 R-PFA-1855185 https://reactome.org/PathwayBrowser/#/R-PFA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 30616 R-PFA-1855193 https://reactome.org/PathwayBrowser/#/R-PFA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 30616 R-PFA-1855194 https://reactome.org/PathwayBrowser/#/R-PFA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 30616 R-PFA-1855206 https://reactome.org/PathwayBrowser/#/R-PFA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 30616 R-PFA-1855207 https://reactome.org/PathwayBrowser/#/R-PFA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 30616 R-PFA-1855216 https://reactome.org/PathwayBrowser/#/R-PFA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Plasmodium falciparum 30616 R-PFA-1855223 https://reactome.org/PathwayBrowser/#/R-PFA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 30616 R-PFA-1855224 https://reactome.org/PathwayBrowser/#/R-PFA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 30616 R-PFA-1855227 https://reactome.org/PathwayBrowser/#/R-PFA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 30616 R-PFA-1855228 https://reactome.org/PathwayBrowser/#/R-PFA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 30616 R-PFA-1855230 https://reactome.org/PathwayBrowser/#/R-PFA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 30616 R-PFA-1855233 https://reactome.org/PathwayBrowser/#/R-PFA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Plasmodium falciparum 30616 R-PFA-193362 https://reactome.org/PathwayBrowser/#/R-PFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Plasmodium falciparum 30616 R-PFA-196753 https://reactome.org/PathwayBrowser/#/R-PFA-196753 2xPPCS ligates PPanK with Cys IEA Plasmodium falciparum 30616 R-PFA-196761 https://reactome.org/PathwayBrowser/#/R-PFA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Plasmodium falciparum 30616 R-PFA-196929 https://reactome.org/PathwayBrowser/#/R-PFA-196929 FLAD1 phosphorylates FMN IEA Plasmodium falciparum 30616 R-PFA-196964 https://reactome.org/PathwayBrowser/#/R-PFA-196964 RFK:Mg2+ phosphorylates RIB IEA Plasmodium falciparum 30616 R-PFA-197271 https://reactome.org/PathwayBrowser/#/R-PFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Plasmodium falciparum 30616 R-PFA-200555 https://reactome.org/PathwayBrowser/#/R-PFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Plasmodium falciparum 30616 R-PFA-200711 https://reactome.org/PathwayBrowser/#/R-PFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Plasmodium falciparum 30616 R-PFA-201035 https://reactome.org/PathwayBrowser/#/R-PFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Plasmodium falciparum 30616 R-PFA-202111 https://reactome.org/PathwayBrowser/#/R-PFA-202111 AKT1 phosphorylates eNOS IEA Plasmodium falciparum 30616 R-PFA-2046085 https://reactome.org/PathwayBrowser/#/R-PFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Plasmodium falciparum 30616 R-PFA-2046098 https://reactome.org/PathwayBrowser/#/R-PFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Plasmodium falciparum 30616 R-PFA-2214351 https://reactome.org/PathwayBrowser/#/R-PFA-2214351 PLK1 phosphorylates GORASP1 IEA Plasmodium falciparum 30616 R-PFA-2294580 https://reactome.org/PathwayBrowser/#/R-PFA-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Plasmodium falciparum 30616 R-PFA-2408551 https://reactome.org/PathwayBrowser/#/R-PFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Plasmodium falciparum 30616 R-PFA-2529020 https://reactome.org/PathwayBrowser/#/R-PFA-2529020 CK2 phosphorylates condensin I subunits IEA Plasmodium falciparum 30616 R-PFA-265783 https://reactome.org/PathwayBrowser/#/R-PFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Plasmodium falciparum 30616 R-PFA-2993814 https://reactome.org/PathwayBrowser/#/R-PFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Plasmodium falciparum 30616 R-PFA-3371422 https://reactome.org/PathwayBrowser/#/R-PFA-3371422 ATP hydrolysis by HSP70 IEA Plasmodium falciparum 30616 R-PFA-3371590 https://reactome.org/PathwayBrowser/#/R-PFA-3371590 HSP70 binds to HSP40:nascent protein IEA Plasmodium falciparum 30616 R-PFA-383190 https://reactome.org/PathwayBrowser/#/R-PFA-383190 HCO3- transport through ion channel IEA Plasmodium falciparum 30616 R-PFA-4167511 https://reactome.org/PathwayBrowser/#/R-PFA-4167511 HLCS biotinylates ACACB IEA Plasmodium falciparum 30616 R-PFA-426240 https://reactome.org/PathwayBrowser/#/R-PFA-426240 DAG kinase produces phosphatidic acid from DAG IEA Plasmodium falciparum 30616 R-PFA-429157 https://reactome.org/PathwayBrowser/#/R-PFA-429157 ABCC4 accumulation of dense granule contents IEA Plasmodium falciparum 30616 R-PFA-429714 https://reactome.org/PathwayBrowser/#/R-PFA-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Plasmodium falciparum 30616 R-PFA-4332358 https://reactome.org/PathwayBrowser/#/R-PFA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Plasmodium falciparum 30616 R-PFA-4332363 https://reactome.org/PathwayBrowser/#/R-PFA-4332363 Autophosphorylation and activation of CAMK2 IEA Plasmodium falciparum 30616 R-PFA-449911 https://reactome.org/PathwayBrowser/#/R-PFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Plasmodium falciparum 30616 R-PFA-450088 https://reactome.org/PathwayBrowser/#/R-PFA-450088 GLUT1 tetramer binds 4xATP IEA Plasmodium falciparum 30616 R-PFA-450092 https://reactome.org/PathwayBrowser/#/R-PFA-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Plasmodium falciparum 30616 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 30616 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 30616 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 30616 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 30616 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 30616 R-PFA-504054 https://reactome.org/PathwayBrowser/#/R-PFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Plasmodium falciparum 30616 R-PFA-5251959 https://reactome.org/PathwayBrowser/#/R-PFA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Plasmodium falciparum 30616 R-PFA-5251989 https://reactome.org/PathwayBrowser/#/R-PFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Plasmodium falciparum 30616 R-PFA-5252079 https://reactome.org/PathwayBrowser/#/R-PFA-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Plasmodium falciparum 30616 R-PFA-5339524 https://reactome.org/PathwayBrowser/#/R-PFA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Plasmodium falciparum 30616 R-PFA-5358510 https://reactome.org/PathwayBrowser/#/R-PFA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Plasmodium falciparum 30616 R-PFA-5358518 https://reactome.org/PathwayBrowser/#/R-PFA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Plasmodium falciparum 30616 R-PFA-5358592 https://reactome.org/PathwayBrowser/#/R-PFA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Plasmodium falciparum 30616 R-PFA-5358597 https://reactome.org/PathwayBrowser/#/R-PFA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Plasmodium falciparum 30616 R-PFA-5358599 https://reactome.org/PathwayBrowser/#/R-PFA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Plasmodium falciparum 30616 R-PFA-5358912 https://reactome.org/PathwayBrowser/#/R-PFA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Plasmodium falciparum 30616 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 30616 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 30616 R-PFA-5618085 https://reactome.org/PathwayBrowser/#/R-PFA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Plasmodium falciparum 30616 R-PFA-5618098 https://reactome.org/PathwayBrowser/#/R-PFA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Plasmodium falciparum 30616 R-PFA-5618099 https://reactome.org/PathwayBrowser/#/R-PFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 30616 R-PFA-5618105 https://reactome.org/PathwayBrowser/#/R-PFA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Plasmodium falciparum 30616 R-PFA-5618107 https://reactome.org/PathwayBrowser/#/R-PFA-5618107 ATP binding to HSP90 triggers conformation change IEA Plasmodium falciparum 30616 R-PFA-5618110 https://reactome.org/PathwayBrowser/#/R-PFA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Plasmodium falciparum 30616 R-PFA-5672948 https://reactome.org/PathwayBrowser/#/R-PFA-5672948 MARK3 phosphorylates KSR1 IEA Plasmodium falciparum 30616 R-PFA-5675194 https://reactome.org/PathwayBrowser/#/R-PFA-5675194 Activated MAPK phosphorylates RAF1 IEA Plasmodium falciparum 30616 R-PFA-5675198 https://reactome.org/PathwayBrowser/#/R-PFA-5675198 Activated MAPKs phosphorylate BRAF IEA Plasmodium falciparum 30616 R-PFA-5678706 https://reactome.org/PathwayBrowser/#/R-PFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Plasmodium falciparum 30616 R-PFA-5678863 https://reactome.org/PathwayBrowser/#/R-PFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Plasmodium falciparum 30616 R-PFA-5682285 https://reactome.org/PathwayBrowser/#/R-PFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Plasmodium falciparum 30616 R-PFA-5683714 https://reactome.org/PathwayBrowser/#/R-PFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Plasmodium falciparum 30616 R-PFA-5683792 https://reactome.org/PathwayBrowser/#/R-PFA-5683792 p-T68-CHEK2 autophosphorylates IEA Plasmodium falciparum 30616 R-PFA-5687094 https://reactome.org/PathwayBrowser/#/R-PFA-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Plasmodium falciparum 30616 R-PFA-5690250 https://reactome.org/PathwayBrowser/#/R-PFA-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Plasmodium falciparum 30616 R-PFA-5690996 https://reactome.org/PathwayBrowser/#/R-PFA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Plasmodium falciparum 30616 R-PFA-5692462 https://reactome.org/PathwayBrowser/#/R-PFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Plasmodium falciparum 30616 R-PFA-5692480 https://reactome.org/PathwayBrowser/#/R-PFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Plasmodium falciparum 30616 R-PFA-5693549 https://reactome.org/PathwayBrowser/#/R-PFA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Plasmodium falciparum 30616 R-PFA-5696839 https://reactome.org/PathwayBrowser/#/R-PFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Plasmodium falciparum 30616 R-PFA-6788798 https://reactome.org/PathwayBrowser/#/R-PFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 30616 R-PFA-6788810 https://reactome.org/PathwayBrowser/#/R-PFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 30616 R-PFA-6798174 https://reactome.org/PathwayBrowser/#/R-PFA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Plasmodium falciparum 30616 R-PFA-6801342 https://reactome.org/PathwayBrowser/#/R-PFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Plasmodium falciparum 30616 R-PFA-6801456 https://reactome.org/PathwayBrowser/#/R-PFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Plasmodium falciparum 30616 R-PFA-6806877 https://reactome.org/PathwayBrowser/#/R-PFA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Plasmodium falciparum 30616 R-PFA-6806967 https://reactome.org/PathwayBrowser/#/R-PFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Plasmodium falciparum 30616 R-PFA-6807868 https://reactome.org/PathwayBrowser/#/R-PFA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Plasmodium falciparum 30616 R-PFA-6811522 https://reactome.org/PathwayBrowser/#/R-PFA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Plasmodium falciparum 30616 R-PFA-6814120 https://reactome.org/PathwayBrowser/#/R-PFA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Plasmodium falciparum 30616 R-PFA-6814124 https://reactome.org/PathwayBrowser/#/R-PFA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Plasmodium falciparum 30616 R-PFA-69063 https://reactome.org/PathwayBrowser/#/R-PFA-69063 Loading of PCNA - Sliding Clamp Formation IEA Plasmodium falciparum 30616 R-PFA-70420 https://reactome.org/PathwayBrowser/#/R-PFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Plasmodium falciparum 30616 R-PFA-70486 https://reactome.org/PathwayBrowser/#/R-PFA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Plasmodium falciparum 30616 R-PFA-70599 https://reactome.org/PathwayBrowser/#/R-PFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Plasmodium falciparum 30616 R-PFA-70997 https://reactome.org/PathwayBrowser/#/R-PFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Plasmodium falciparum 30616 R-PFA-71401 https://reactome.org/PathwayBrowser/#/R-PFA-71401 OGDH dimer decarboxylates 2-OG IEA Plasmodium falciparum 30616 R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 30616 R-PFA-71735 https://reactome.org/PathwayBrowser/#/R-PFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Plasmodium falciparum 30616 R-PFA-71850 https://reactome.org/PathwayBrowser/#/R-PFA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Plasmodium falciparum 30616 R-PFA-72621 https://reactome.org/PathwayBrowser/#/R-PFA-72621 Ribosomal scanning IEA Plasmodium falciparum 30616 R-PFA-72647 https://reactome.org/PathwayBrowser/#/R-PFA-72647 Cap-bound mRNA is activated by helicases IEA Plasmodium falciparum 30616 R-PFA-73548 https://reactome.org/PathwayBrowser/#/R-PFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Plasmodium falciparum 30616 R-PFA-73577 https://reactome.org/PathwayBrowser/#/R-PFA-73577 CAD hexamer transforms L-Gln to CAP IEA Plasmodium falciparum 30616 R-PFA-73580 https://reactome.org/PathwayBrowser/#/R-PFA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Plasmodium falciparum 30616 R-PFA-73635 https://reactome.org/PathwayBrowser/#/R-PFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Plasmodium falciparum 30616 R-PFA-73647 https://reactome.org/PathwayBrowser/#/R-PFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Plasmodium falciparum 30616 R-PFA-73788 https://reactome.org/PathwayBrowser/#/R-PFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Plasmodium falciparum 30616 R-PFA-73792 https://reactome.org/PathwayBrowser/#/R-PFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Plasmodium falciparum 30616 R-PFA-75125 https://reactome.org/PathwayBrowser/#/R-PFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Plasmodium falciparum 30616 R-PFA-75126 https://reactome.org/PathwayBrowser/#/R-PFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Plasmodium falciparum 30616 R-PFA-75851 https://reactome.org/PathwayBrowser/#/R-PFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 30616 R-PFA-75887 https://reactome.org/PathwayBrowser/#/R-PFA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Plasmodium falciparum 30616 R-PFA-77071 https://reactome.org/PathwayBrowser/#/R-PFA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Plasmodium falciparum 30616 R-PFA-8848053 https://reactome.org/PathwayBrowser/#/R-PFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Plasmodium falciparum 30616 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 30616 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 30616 R-PFA-8852128 https://reactome.org/PathwayBrowser/#/R-PFA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Plasmodium falciparum 30616 R-PFA-8852131 https://reactome.org/PathwayBrowser/#/R-PFA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Plasmodium falciparum 30616 R-PFA-8852132 https://reactome.org/PathwayBrowser/#/R-PFA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Plasmodium falciparum 30616 R-PFA-8852134 https://reactome.org/PathwayBrowser/#/R-PFA-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Plasmodium falciparum 30616 R-PFA-8865774 https://reactome.org/PathwayBrowser/#/R-PFA-8865774 TTLLs polyglutamylate tubulin IEA Plasmodium falciparum 30616 R-PFA-8866405 https://reactome.org/PathwayBrowser/#/R-PFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 30616 R-PFA-8868066 https://reactome.org/PathwayBrowser/#/R-PFA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Plasmodium falciparum 30616 R-PFA-8876889 https://reactome.org/PathwayBrowser/#/R-PFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 30616 R-PFA-8951648 https://reactome.org/PathwayBrowser/#/R-PFA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Plasmodium falciparum 30616 R-PFA-8951656 https://reactome.org/PathwayBrowser/#/R-PFA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Plasmodium falciparum 30616 R-PFA-8955030 https://reactome.org/PathwayBrowser/#/R-PFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Plasmodium falciparum 30616 R-PFA-8959510 https://reactome.org/PathwayBrowser/#/R-PFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Plasmodium falciparum 30616 R-PFA-9012319 https://reactome.org/PathwayBrowser/#/R-PFA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Plasmodium falciparum 30616 R-PFA-917841 https://reactome.org/PathwayBrowser/#/R-PFA-917841 Acidification of Tf:TfR1 containing endosome IEA Plasmodium falciparum 30616 R-PFA-917979 https://reactome.org/PathwayBrowser/#/R-PFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Plasmodium falciparum 30616 R-PFA-927889 https://reactome.org/PathwayBrowser/#/R-PFA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Plasmodium falciparum 30616 R-PFA-936883 https://reactome.org/PathwayBrowser/#/R-PFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Plasmodium falciparum 30616 R-PFA-936895 https://reactome.org/PathwayBrowser/#/R-PFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Plasmodium falciparum 30616 R-PFA-939763 https://reactome.org/PathwayBrowser/#/R-PFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Plasmodium falciparum 30616 R-PFA-947591 https://reactome.org/PathwayBrowser/#/R-PFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Plasmodium falciparum 30616 R-PFA-9606884 https://reactome.org/PathwayBrowser/#/R-PFA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Plasmodium falciparum 30616 R-PFA-964958 https://reactome.org/PathwayBrowser/#/R-PFA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Plasmodium falciparum 30616 R-PFA-964962 https://reactome.org/PathwayBrowser/#/R-PFA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Plasmodium falciparum 30616 R-PFA-964970 https://reactome.org/PathwayBrowser/#/R-PFA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Plasmodium falciparum 30616 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 30616 R-PFA-9661417 https://reactome.org/PathwayBrowser/#/R-PFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Plasmodium falciparum 30616 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 30616 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 30616 R-PFA-9705925 https://reactome.org/PathwayBrowser/#/R-PFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Plasmodium falciparum 30616 R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 30616 R-PFA-9706837 https://reactome.org/PathwayBrowser/#/R-PFA-9706837 AR binds AR antagonists IEA Plasmodium falciparum 30616 R-PFA-9725855 https://reactome.org/PathwayBrowser/#/R-PFA-9725855 NR3C2 binds NR3C2 antagonists IEA Plasmodium falciparum 30616 R-PFA-9725885 https://reactome.org/PathwayBrowser/#/R-PFA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Plasmodium falciparum 30616 R-PFA-9726509 https://reactome.org/PathwayBrowser/#/R-PFA-9726509 NR3C2 binds fludrocortisone IEA Plasmodium falciparum 30616 R-PFA-9726580 https://reactome.org/PathwayBrowser/#/R-PFA-9726580 PGR binds PGR agonists IEA Plasmodium falciparum 30616 R-PFA-9726621 https://reactome.org/PathwayBrowser/#/R-PFA-9726621 PGR binds PGR antagonists IEA Plasmodium falciparum 30616 R-PFA-9748949 https://reactome.org/PathwayBrowser/#/R-PFA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Plasmodium falciparum 30616 R-PFA-9748957 https://reactome.org/PathwayBrowser/#/R-PFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Plasmodium falciparum 30616 R-PFA-9748963 https://reactome.org/PathwayBrowser/#/R-PFA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Plasmodium falciparum 30616 R-PFA-9748969 https://reactome.org/PathwayBrowser/#/R-PFA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Plasmodium falciparum 30616 R-PFA-9748999 https://reactome.org/PathwayBrowser/#/R-PFA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Plasmodium falciparum 30616 R-PFA-9750546 https://reactome.org/PathwayBrowser/#/R-PFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Plasmodium falciparum 30616 R-PFA-9753278 https://reactome.org/PathwayBrowser/#/R-PFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 30616 R-PFA-9753283 https://reactome.org/PathwayBrowser/#/R-PFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 30616 R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 30616 R-PFA-9755013 https://reactome.org/PathwayBrowser/#/R-PFA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Plasmodium falciparum 30616 R-PFA-9759454 https://reactome.org/PathwayBrowser/#/R-PFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Plasmodium falciparum 30616 R-PFA-9759461 https://reactome.org/PathwayBrowser/#/R-PFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Plasmodium falciparum 30616 R-PFA-9794120 https://reactome.org/PathwayBrowser/#/R-PFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Plasmodium falciparum 30616 R-PFA-9794572 https://reactome.org/PathwayBrowser/#/R-PFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Plasmodium falciparum 30616 R-PFA-983140 https://reactome.org/PathwayBrowser/#/R-PFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Plasmodium falciparum 30616 R-PFA-983153 https://reactome.org/PathwayBrowser/#/R-PFA-983153 E1 mediated ubiquitin activation IEA Plasmodium falciparum 30616 R-PFA-983156 https://reactome.org/PathwayBrowser/#/R-PFA-983156 Polyubiquitination of substrate IEA Plasmodium falciparum 30616 R-PFA-9837337 https://reactome.org/PathwayBrowser/#/R-PFA-9837337 DCAKD phosphorylates DP-CoA IEA Plasmodium falciparum 30616 R-PFA-9839105 https://reactome.org/PathwayBrowser/#/R-PFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Plasmodium falciparum 30616 R-PFA-9843721 https://reactome.org/PathwayBrowser/#/R-PFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Plasmodium falciparum 30616 R-RNO-109624 https://reactome.org/PathwayBrowser/#/R-RNO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Rattus norvegicus 30616 R-RNO-109671 https://reactome.org/PathwayBrowser/#/R-RNO-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Rattus norvegicus 30616 R-RNO-109699 https://reactome.org/PathwayBrowser/#/R-RNO-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-109702 https://reactome.org/PathwayBrowser/#/R-RNO-109702 PDPK1 phosphorylates AKT2 IEA Rattus norvegicus 30616 R-RNO-109759 https://reactome.org/PathwayBrowser/#/R-RNO-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Rattus norvegicus 30616 R-RNO-109822 https://reactome.org/PathwayBrowser/#/R-RNO-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Rattus norvegicus 30616 R-RNO-109823 https://reactome.org/PathwayBrowser/#/R-RNO-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Rattus norvegicus 30616 R-RNO-109860 https://reactome.org/PathwayBrowser/#/R-RNO-109860 MAP2K1 phosphorylates MAPK3 IEA Rattus norvegicus 30616 R-RNO-109862 https://reactome.org/PathwayBrowser/#/R-RNO-109862 MAP2K2 phosphorylates MAPK1 IEA Rattus norvegicus 30616 R-RNO-109903 https://reactome.org/PathwayBrowser/#/R-RNO-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Rattus norvegicus 30616 R-RNO-110133 https://reactome.org/PathwayBrowser/#/R-RNO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Rattus norvegicus 30616 R-RNO-110137 https://reactome.org/PathwayBrowser/#/R-RNO-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Rattus norvegicus 30616 R-RNO-110138 https://reactome.org/PathwayBrowser/#/R-RNO-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 30616 R-RNO-110141 https://reactome.org/PathwayBrowser/#/R-RNO-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Rattus norvegicus 30616 R-RNO-110144 https://reactome.org/PathwayBrowser/#/R-RNO-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Rattus norvegicus 30616 R-RNO-110145 https://reactome.org/PathwayBrowser/#/R-RNO-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Rattus norvegicus 30616 R-RNO-1112510 https://reactome.org/PathwayBrowser/#/R-RNO-1112510 IL6ST is tyrosine phosphorylated IEA Rattus norvegicus 30616 R-RNO-1112514 https://reactome.org/PathwayBrowser/#/R-RNO-1112514 JAK activation IEA Rattus norvegicus 30616 R-RNO-1112602 https://reactome.org/PathwayBrowser/#/R-RNO-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Rattus norvegicus 30616 R-RNO-1112703 https://reactome.org/PathwayBrowser/#/R-RNO-1112703 PTPN11 is phosphorylated IEA Rattus norvegicus 30616 R-RNO-1112727 https://reactome.org/PathwayBrowser/#/R-RNO-1112727 Serine phosphorylation of STATs IEA Rattus norvegicus 30616 R-RNO-111742 https://reactome.org/PathwayBrowser/#/R-RNO-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 30616 R-RNO-111751 https://reactome.org/PathwayBrowser/#/R-RNO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 30616 R-RNO-111804 https://reactome.org/PathwayBrowser/#/R-RNO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 30616 R-RNO-111898 https://reactome.org/PathwayBrowser/#/R-RNO-111898 Phosphorylation of cPLA2 by ERK-2 IEA Rattus norvegicus 30616 R-RNO-111915 https://reactome.org/PathwayBrowser/#/R-RNO-111915 CAMK4 autophosphorylates IEA Rattus norvegicus 30616 R-RNO-111930 https://reactome.org/PathwayBrowser/#/R-RNO-111930 Adenylate cyclase produces cAMP IEA Rattus norvegicus 30616 R-RNO-111970 https://reactome.org/PathwayBrowser/#/R-RNO-111970 PKC phosphorylates GRK2 IEA Rattus norvegicus 30616 R-RNO-112342 https://reactome.org/PathwayBrowser/#/R-RNO-112342 Inactivation of MAP2K1 by CDK1 IEA Rattus norvegicus 30616 R-RNO-112381 https://reactome.org/PathwayBrowser/#/R-RNO-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Rattus norvegicus 30616 R-RNO-114252 https://reactome.org/PathwayBrowser/#/R-RNO-114252 Cleavage of Procaspase-3 by the apoptosome IEA Rattus norvegicus 30616 R-RNO-114254 https://reactome.org/PathwayBrowser/#/R-RNO-114254 CYCS binds to APAF1 IEA Rattus norvegicus 30616 R-RNO-114256 https://reactome.org/PathwayBrowser/#/R-RNO-114256 CYCS:APAF1 binds procaspase-9 IEA Rattus norvegicus 30616 R-RNO-114261 https://reactome.org/PathwayBrowser/#/R-RNO-114261 Cleavage of Procaspase-7 by the apoptosome IEA Rattus norvegicus 30616 R-RNO-114600 https://reactome.org/PathwayBrowser/#/R-RNO-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Rattus norvegicus 30616 R-RNO-114683 https://reactome.org/PathwayBrowser/#/R-RNO-114683 Phosphorylation of Platelet Sec-1 IEA Rattus norvegicus 30616 R-RNO-114684 https://reactome.org/PathwayBrowser/#/R-RNO-114684 Phosphorylation of Syntaxin-4 IEA Rattus norvegicus 30616 R-RNO-1168459 https://reactome.org/PathwayBrowser/#/R-RNO-1168459 Lyn activates ERK IEA Rattus norvegicus 30616 R-RNO-1168635 https://reactome.org/PathwayBrowser/#/R-RNO-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Rattus norvegicus 30616 R-RNO-1168638 https://reactome.org/PathwayBrowser/#/R-RNO-1168638 Activated IKK phosphorylates I-kappaB IEA Rattus norvegicus 30616 R-RNO-1168854 https://reactome.org/PathwayBrowser/#/R-RNO-1168854 JAK2 phosphorylation of Irs-1/2 TAS Rattus norvegicus 30616 R-RNO-1169394 https://reactome.org/PathwayBrowser/#/R-RNO-1169394 ISGylation of IRF3 IEA Rattus norvegicus 30616 R-RNO-1169397 https://reactome.org/PathwayBrowser/#/R-RNO-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Rattus norvegicus 30616 R-RNO-1169398 https://reactome.org/PathwayBrowser/#/R-RNO-1169398 ISGylation of host protein filamin B IEA Rattus norvegicus 30616 R-RNO-1169402 https://reactome.org/PathwayBrowser/#/R-RNO-1169402 ISGylation of E2 conjugating enzymes IEA Rattus norvegicus 30616 R-RNO-1169405 https://reactome.org/PathwayBrowser/#/R-RNO-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Rattus norvegicus 30616 R-RNO-1169406 https://reactome.org/PathwayBrowser/#/R-RNO-1169406 ISGylation of host proteins IEA Rattus norvegicus 30616 R-RNO-1181149 https://reactome.org/PathwayBrowser/#/R-RNO-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Rattus norvegicus 30616 R-RNO-1226094 https://reactome.org/PathwayBrowser/#/R-RNO-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Rattus norvegicus 30616 R-RNO-1226095 https://reactome.org/PathwayBrowser/#/R-RNO-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Rattus norvegicus 30616 R-RNO-1247935 https://reactome.org/PathwayBrowser/#/R-RNO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Rattus norvegicus 30616 R-RNO-1247960 https://reactome.org/PathwayBrowser/#/R-RNO-1247960 Activation of p38 MAPK IEA Rattus norvegicus 30616 R-RNO-1250195 https://reactome.org/PathwayBrowser/#/R-RNO-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Rattus norvegicus 30616 R-RNO-1250315 https://reactome.org/PathwayBrowser/#/R-RNO-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Rattus norvegicus 30616 R-RNO-1250348 https://reactome.org/PathwayBrowser/#/R-RNO-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Rattus norvegicus 30616 R-RNO-1250370 https://reactome.org/PathwayBrowser/#/R-RNO-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Rattus norvegicus 30616 R-RNO-1250462 https://reactome.org/PathwayBrowser/#/R-RNO-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Rattus norvegicus 30616 R-RNO-1295540 https://reactome.org/PathwayBrowser/#/R-RNO-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Rattus norvegicus 30616 R-RNO-1295609 https://reactome.org/PathwayBrowser/#/R-RNO-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Rattus norvegicus 30616 R-RNO-1296024 https://reactome.org/PathwayBrowser/#/R-RNO-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Rattus norvegicus 30616 R-RNO-1306957 https://reactome.org/PathwayBrowser/#/R-RNO-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Rattus norvegicus 30616 R-RNO-1306979 https://reactome.org/PathwayBrowser/#/R-RNO-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Rattus norvegicus 30616 R-RNO-1307963 https://reactome.org/PathwayBrowser/#/R-RNO-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Rattus norvegicus 30616 R-RNO-1358791 https://reactome.org/PathwayBrowser/#/R-RNO-1358791 Phosphorylation of USP8 by P-AKT IEA Rattus norvegicus 30616 R-RNO-1362270 https://reactome.org/PathwayBrowser/#/R-RNO-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Rattus norvegicus 30616 R-RNO-1369028 https://reactome.org/PathwayBrowser/#/R-RNO-1369028 ABCAs mediate lipid efflux IEA Rattus norvegicus 30616 R-RNO-1369052 https://reactome.org/PathwayBrowser/#/R-RNO-1369052 ABCAs mediate lipid influx IEA Rattus norvegicus 30616 R-RNO-1369065 https://reactome.org/PathwayBrowser/#/R-RNO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Rattus norvegicus 30616 R-RNO-1369099 https://reactome.org/PathwayBrowser/#/R-RNO-1369099 Shp2 is phosphorylated TAS Rattus norvegicus 30616 R-RNO-1369121 https://reactome.org/PathwayBrowser/#/R-RNO-1369121 Tyrosine phosphorylation of Prlr TAS Rattus norvegicus 30616 R-RNO-1370505 https://reactome.org/PathwayBrowser/#/R-RNO-1370505 PRLR is phosphorylated at Ser-349 IEA Rattus norvegicus 30616 R-RNO-139855 https://reactome.org/PathwayBrowser/#/R-RNO-139855 P2X1-mediated entry of Ca++ from plasma IEA Rattus norvegicus 30616 R-RNO-139908 https://reactome.org/PathwayBrowser/#/R-RNO-139908 Phosphorylation of DLC2 by MAPK8 IEA Rattus norvegicus 30616 R-RNO-139918 https://reactome.org/PathwayBrowser/#/R-RNO-139918 Phosphorylation of BIM by JNK IEA Rattus norvegicus 30616 R-RNO-1433418 https://reactome.org/PathwayBrowser/#/R-RNO-1433418 Phosphorylation of JAK2 IEA Rattus norvegicus 30616 R-RNO-1433454 https://reactome.org/PathwayBrowser/#/R-RNO-1433454 Phosphorylation of GAB2 by SFKs IEA Rattus norvegicus 30616 R-RNO-1433488 https://reactome.org/PathwayBrowser/#/R-RNO-1433488 Phosphorylation of SHP2 by SFKs IEA Rattus norvegicus 30616 R-RNO-1433506 https://reactome.org/PathwayBrowser/#/R-RNO-1433506 Phosphorylation of APS IEA Rattus norvegicus 30616 R-RNO-1433508 https://reactome.org/PathwayBrowser/#/R-RNO-1433508 PKC alpha interacts with and phosphorylates KIT IEA Rattus norvegicus 30616 R-RNO-1433514 https://reactome.org/PathwayBrowser/#/R-RNO-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Rattus norvegicus 30616 R-RNO-1433542 https://reactome.org/PathwayBrowser/#/R-RNO-1433542 Phosphorylation and activation of VAV1 IEA Rattus norvegicus 30616 R-RNO-1454916 https://reactome.org/PathwayBrowser/#/R-RNO-1454916 The ABCC family mediates organic anion transport IEA Rattus norvegicus 30616 R-RNO-1454928 https://reactome.org/PathwayBrowser/#/R-RNO-1454928 ABCG4 may mediate cholesterol efflux IEA Rattus norvegicus 30616 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-1470009 https://reactome.org/PathwayBrowser/#/R-RNO-1470009 Phosphorylation of STATs IEA Rattus norvegicus 30616 R-RNO-1472121 https://reactome.org/PathwayBrowser/#/R-RNO-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Rattus norvegicus 30616 R-RNO-1475422 https://reactome.org/PathwayBrowser/#/R-RNO-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Rattus norvegicus 30616 R-RNO-1483004 https://reactome.org/PathwayBrowser/#/R-RNO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Rattus norvegicus 30616 R-RNO-1483222 https://reactome.org/PathwayBrowser/#/R-RNO-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Rattus norvegicus 30616 R-RNO-1497853 https://reactome.org/PathwayBrowser/#/R-RNO-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Rattus norvegicus 30616 R-RNO-1524186 https://reactome.org/PathwayBrowser/#/R-RNO-1524186 Phosphorylation of PLCgamma by PDGFR IEA Rattus norvegicus 30616 R-RNO-1549526 https://reactome.org/PathwayBrowser/#/R-RNO-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Rattus norvegicus 30616 R-RNO-156673 https://reactome.org/PathwayBrowser/#/R-RNO-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Rattus norvegicus 30616 R-RNO-156678 https://reactome.org/PathwayBrowser/#/R-RNO-156678 Activation of Cdc25C IEA Rattus norvegicus 30616 R-RNO-156682 https://reactome.org/PathwayBrowser/#/R-RNO-156682 PLK1 phosphorylates NUDC IEA Rattus norvegicus 30616 R-RNO-156699 https://reactome.org/PathwayBrowser/#/R-RNO-156699 Inactivation of Wee1 kinase IEA Rattus norvegicus 30616 R-RNO-156723 https://reactome.org/PathwayBrowser/#/R-RNO-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Rattus norvegicus 30616 R-RNO-159101 https://reactome.org/PathwayBrowser/#/R-RNO-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Rattus norvegicus 30616 R-RNO-159425 https://reactome.org/PathwayBrowser/#/R-RNO-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 30616 R-RNO-159443 https://reactome.org/PathwayBrowser/#/R-RNO-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 30616 R-RNO-159567 https://reactome.org/PathwayBrowser/#/R-RNO-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Rattus norvegicus 30616 R-RNO-162657 https://reactome.org/PathwayBrowser/#/R-RNO-162657 Inactivation of Myt1 kinase IEA Rattus norvegicus 30616 R-RNO-163010 https://reactome.org/PathwayBrowser/#/R-RNO-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Rattus norvegicus 30616 R-RNO-163120 https://reactome.org/PathwayBrowser/#/R-RNO-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Rattus norvegicus 30616 R-RNO-163215 https://reactome.org/PathwayBrowser/#/R-RNO-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Rattus norvegicus 30616 R-RNO-1632857 https://reactome.org/PathwayBrowser/#/R-RNO-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Rattus norvegicus 30616 R-RNO-163472 https://reactome.org/PathwayBrowser/#/R-RNO-163472 hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP TAS Rattus norvegicus 30616 R-RNO-163601 https://reactome.org/PathwayBrowser/#/R-RNO-163601 perilipin + 3 ATP -> phosphorylated perilipin + 3 ADP TAS Rattus norvegicus 30616 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus 30616 R-RNO-1638845 https://reactome.org/PathwayBrowser/#/R-RNO-1638845 CERK phosphorylates CERA to form C1P IEA Rattus norvegicus 30616 R-RNO-164832 https://reactome.org/PathwayBrowser/#/R-RNO-164832 ATPase synthesizes ATP IEA Rattus norvegicus 30616 R-RNO-164834 https://reactome.org/PathwayBrowser/#/R-RNO-164834 Enzyme-bound ATP is released IEA Rattus norvegicus 30616 R-RNO-165162 https://reactome.org/PathwayBrowser/#/R-RNO-165162 Phosphorylation of TSC2 by PKB IEA Rattus norvegicus 30616 R-RNO-165182 https://reactome.org/PathwayBrowser/#/R-RNO-165182 Phosphorylation of complexed TSC2 by PKB IEA Rattus norvegicus 30616 R-RNO-165692 https://reactome.org/PathwayBrowser/#/R-RNO-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Rattus norvegicus 30616 R-RNO-165718 https://reactome.org/PathwayBrowser/#/R-RNO-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Rattus norvegicus 30616 R-RNO-165726 https://reactome.org/PathwayBrowser/#/R-RNO-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Rattus norvegicus 30616 R-RNO-165758 https://reactome.org/PathwayBrowser/#/R-RNO-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Rattus norvegicus 30616 R-RNO-165766 https://reactome.org/PathwayBrowser/#/R-RNO-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Rattus norvegicus 30616 R-RNO-166245 https://reactome.org/PathwayBrowser/#/R-RNO-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Rattus norvegicus 30616 R-RNO-1671699 https://reactome.org/PathwayBrowser/#/R-RNO-1671699 Prlr-bound Stat5 is phosphorylated TAS Rattus norvegicus 30616 R-RNO-1675773 https://reactome.org/PathwayBrowser/#/R-RNO-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Rattus norvegicus 30616 R-RNO-1675776 https://reactome.org/PathwayBrowser/#/R-RNO-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Rattus norvegicus 30616 R-RNO-1675780 https://reactome.org/PathwayBrowser/#/R-RNO-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Rattus norvegicus 30616 R-RNO-1675810 https://reactome.org/PathwayBrowser/#/R-RNO-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Rattus norvegicus 30616 R-RNO-1675813 https://reactome.org/PathwayBrowser/#/R-RNO-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Rattus norvegicus 30616 R-RNO-1675883 https://reactome.org/PathwayBrowser/#/R-RNO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Rattus norvegicus 30616 R-RNO-1675928 https://reactome.org/PathwayBrowser/#/R-RNO-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Rattus norvegicus 30616 R-RNO-1675939 https://reactome.org/PathwayBrowser/#/R-RNO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Rattus norvegicus 30616 R-RNO-1675961 https://reactome.org/PathwayBrowser/#/R-RNO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Rattus norvegicus 30616 R-RNO-1675974 https://reactome.org/PathwayBrowser/#/R-RNO-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Rattus norvegicus 30616 R-RNO-1676024 https://reactome.org/PathwayBrowser/#/R-RNO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Rattus norvegicus 30616 R-RNO-1676048 https://reactome.org/PathwayBrowser/#/R-RNO-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Rattus norvegicus 30616 R-RNO-1676082 https://reactome.org/PathwayBrowser/#/R-RNO-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Rattus norvegicus 30616 R-RNO-1676109 https://reactome.org/PathwayBrowser/#/R-RNO-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Rattus norvegicus 30616 R-RNO-1676134 https://reactome.org/PathwayBrowser/#/R-RNO-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Rattus norvegicus 30616 R-RNO-1676145 https://reactome.org/PathwayBrowser/#/R-RNO-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Rattus norvegicus 30616 R-RNO-1676185 https://reactome.org/PathwayBrowser/#/R-RNO-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Rattus norvegicus 30616 R-RNO-1676206 https://reactome.org/PathwayBrowser/#/R-RNO-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Rattus norvegicus 30616 R-RNO-1678923 https://reactome.org/PathwayBrowser/#/R-RNO-1678923 TLR folding by chaperones GP96 and CNPY3 IEA Rattus norvegicus 30616 R-RNO-1678944 https://reactome.org/PathwayBrowser/#/R-RNO-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Rattus norvegicus 30616 R-RNO-168053 https://reactome.org/PathwayBrowser/#/R-RNO-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Rattus norvegicus 30616 R-RNO-168136 https://reactome.org/PathwayBrowser/#/R-RNO-168136 Activated JNKs phosphorylate c-JUN IEA Rattus norvegicus 30616 R-RNO-168140 https://reactome.org/PathwayBrowser/#/R-RNO-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Rattus norvegicus 30616 R-RNO-168162 https://reactome.org/PathwayBrowser/#/R-RNO-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Rattus norvegicus 30616 R-RNO-169905 https://reactome.org/PathwayBrowser/#/R-RNO-169905 ARMS is phosphorylated by active TrkA receptor IEA Rattus norvegicus 30616 R-RNO-170026 https://reactome.org/PathwayBrowser/#/R-RNO-170026 Protons are translocated from the intermembrane space to the matrix IEA Rattus norvegicus 30616 R-RNO-170055 https://reactome.org/PathwayBrowser/#/R-RNO-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Rattus norvegicus 30616 R-RNO-170070 https://reactome.org/PathwayBrowser/#/R-RNO-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Rattus norvegicus 30616 R-RNO-170076 https://reactome.org/PathwayBrowser/#/R-RNO-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Rattus norvegicus 30616 R-RNO-170087 https://reactome.org/PathwayBrowser/#/R-RNO-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Rattus norvegicus 30616 R-RNO-170126 https://reactome.org/PathwayBrowser/#/R-RNO-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Rattus norvegicus 30616 R-RNO-170676 https://reactome.org/PathwayBrowser/#/R-RNO-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Rattus norvegicus 30616 R-RNO-170843 https://reactome.org/PathwayBrowser/#/R-RNO-170843 TGFBR2 phosphorylates TGFBR1 IEA Rattus norvegicus 30616 R-RNO-170868 https://reactome.org/PathwayBrowser/#/R-RNO-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Rattus norvegicus 30616 R-RNO-170977 https://reactome.org/PathwayBrowser/#/R-RNO-170977 FRS2 is phosphorylated by active TrkA receptor IEA Rattus norvegicus 30616 R-RNO-174079 https://reactome.org/PathwayBrowser/#/R-RNO-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Rattus norvegicus 30616 R-RNO-174122 https://reactome.org/PathwayBrowser/#/R-RNO-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Rattus norvegicus 30616 R-RNO-174164 https://reactome.org/PathwayBrowser/#/R-RNO-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Rattus norvegicus 30616 R-RNO-174174 https://reactome.org/PathwayBrowser/#/R-RNO-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Rattus norvegicus 30616 R-RNO-174251 https://reactome.org/PathwayBrowser/#/R-RNO-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Rattus norvegicus 30616 R-RNO-174367 https://reactome.org/PathwayBrowser/#/R-RNO-174367 GCL ligates L-Glu to L-Cys IEA Rattus norvegicus 30616 R-RNO-174389 https://reactome.org/PathwayBrowser/#/R-RNO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Rattus norvegicus 30616 R-RNO-174391 https://reactome.org/PathwayBrowser/#/R-RNO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Rattus norvegicus 30616 R-RNO-174392 https://reactome.org/PathwayBrowser/#/R-RNO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Rattus norvegicus 30616 R-RNO-174394 https://reactome.org/PathwayBrowser/#/R-RNO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Rattus norvegicus 30616 R-RNO-174438 https://reactome.org/PathwayBrowser/#/R-RNO-174438 Formation of the Flap Intermediate on the C-strand IEA Rattus norvegicus 30616 R-RNO-174439 https://reactome.org/PathwayBrowser/#/R-RNO-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Rattus norvegicus 30616 R-RNO-176116 https://reactome.org/PathwayBrowser/#/R-RNO-176116 Recruitment and activation of Chk1 IEA Rattus norvegicus 30616 R-RNO-176298 https://reactome.org/PathwayBrowser/#/R-RNO-176298 Activation of claspin IEA Rattus norvegicus 30616 R-RNO-177157 https://reactome.org/PathwayBrowser/#/R-RNO-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 30616 R-RNO-177275 https://reactome.org/PathwayBrowser/#/R-RNO-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Rattus norvegicus 30616 R-RNO-177284 https://reactome.org/PathwayBrowser/#/R-RNO-177284 PKA phosphorylates PDE4B IEA Rattus norvegicus 30616 R-RNO-177930 https://reactome.org/PathwayBrowser/#/R-RNO-177930 GAB1 phosphorylation by EGFR kinase IEA Rattus norvegicus 30616 R-RNO-177933 https://reactome.org/PathwayBrowser/#/R-RNO-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Rattus norvegicus 30616 R-RNO-177934 https://reactome.org/PathwayBrowser/#/R-RNO-177934 EGFR autophosphorylation IEA Rattus norvegicus 30616 R-RNO-177937 https://reactome.org/PathwayBrowser/#/R-RNO-177937 Phosphorylation of EGFR by SRC kinase IEA Rattus norvegicus 30616 R-RNO-177939 https://reactome.org/PathwayBrowser/#/R-RNO-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Rattus norvegicus 30616 R-RNO-181812 https://reactome.org/PathwayBrowser/#/R-RNO-181812 Trk receptor autophosphorylates TAS Rattus norvegicus 30616 R-RNO-182072 https://reactome.org/PathwayBrowser/#/R-RNO-182072 Active Trk phosphorylates Plcg1 TAS Rattus norvegicus 30616 R-RNO-182969 https://reactome.org/PathwayBrowser/#/R-RNO-182969 Phosphorylation of CBL (EGFR:CBL) IEA Rattus norvegicus 30616 R-RNO-183058 https://reactome.org/PathwayBrowser/#/R-RNO-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Rattus norvegicus 30616 R-RNO-1855153 https://reactome.org/PathwayBrowser/#/R-RNO-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855157 https://reactome.org/PathwayBrowser/#/R-RNO-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Rattus norvegicus 30616 R-RNO-1855158 https://reactome.org/PathwayBrowser/#/R-RNO-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855162 https://reactome.org/PathwayBrowser/#/R-RNO-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855169 https://reactome.org/PathwayBrowser/#/R-RNO-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855172 https://reactome.org/PathwayBrowser/#/R-RNO-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855176 https://reactome.org/PathwayBrowser/#/R-RNO-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Rattus norvegicus 30616 R-RNO-1855179 https://reactome.org/PathwayBrowser/#/R-RNO-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855181 https://reactome.org/PathwayBrowser/#/R-RNO-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Rattus norvegicus 30616 R-RNO-1855182 https://reactome.org/PathwayBrowser/#/R-RNO-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855185 https://reactome.org/PathwayBrowser/#/R-RNO-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 30616 R-RNO-1855193 https://reactome.org/PathwayBrowser/#/R-RNO-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855194 https://reactome.org/PathwayBrowser/#/R-RNO-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855197 https://reactome.org/PathwayBrowser/#/R-RNO-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855206 https://reactome.org/PathwayBrowser/#/R-RNO-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 30616 R-RNO-1855207 https://reactome.org/PathwayBrowser/#/R-RNO-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Rattus norvegicus 30616 R-RNO-1855216 https://reactome.org/PathwayBrowser/#/R-RNO-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855223 https://reactome.org/PathwayBrowser/#/R-RNO-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855224 https://reactome.org/PathwayBrowser/#/R-RNO-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Rattus norvegicus 30616 R-RNO-1855227 https://reactome.org/PathwayBrowser/#/R-RNO-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Rattus norvegicus 30616 R-RNO-1855228 https://reactome.org/PathwayBrowser/#/R-RNO-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 30616 R-RNO-1855230 https://reactome.org/PathwayBrowser/#/R-RNO-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Rattus norvegicus 30616 R-RNO-1855233 https://reactome.org/PathwayBrowser/#/R-RNO-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Rattus norvegicus 30616 R-RNO-1861595 https://reactome.org/PathwayBrowser/#/R-RNO-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Rattus norvegicus 30616 R-RNO-186786 https://reactome.org/PathwayBrowser/#/R-RNO-186786 Autophosphorylation of PDGF beta receptors IEA Rattus norvegicus 30616 R-RNO-186800 https://reactome.org/PathwayBrowser/#/R-RNO-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-187520 https://reactome.org/PathwayBrowser/#/R-RNO-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Rattus norvegicus 30616 R-RNO-187682 https://reactome.org/PathwayBrowser/#/R-RNO-187682 Binding and activation of MAP kinase TAS Rattus norvegicus 30616 R-RNO-187688 https://reactome.org/PathwayBrowser/#/R-RNO-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Rattus norvegicus 30616 R-RNO-187916 https://reactome.org/PathwayBrowser/#/R-RNO-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Rattus norvegicus 30616 R-RNO-187948 https://reactome.org/PathwayBrowser/#/R-RNO-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Rattus norvegicus 30616 R-RNO-187949 https://reactome.org/PathwayBrowser/#/R-RNO-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Rattus norvegicus 30616 R-RNO-187959 https://reactome.org/PathwayBrowser/#/R-RNO-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Rattus norvegicus 30616 R-RNO-188350 https://reactome.org/PathwayBrowser/#/R-RNO-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Rattus norvegicus 30616 R-RNO-188390 https://reactome.org/PathwayBrowser/#/R-RNO-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Rattus norvegicus 30616 R-RNO-190326 https://reactome.org/PathwayBrowser/#/R-RNO-190326 Autocatalytic phosphorylation of FGFR4 IEA Rattus norvegicus 30616 R-RNO-190385 https://reactome.org/PathwayBrowser/#/R-RNO-190385 Autocatalytic phosphorylation of FGFR3b IEA Rattus norvegicus 30616 R-RNO-190388 https://reactome.org/PathwayBrowser/#/R-RNO-190388 Autocatalytic phosphorylation of FGFR3c IEA Rattus norvegicus 30616 R-RNO-190408 https://reactome.org/PathwayBrowser/#/R-RNO-190408 Autocatalytic phosphorylation of FGFR2b IEA Rattus norvegicus 30616 R-RNO-190413 https://reactome.org/PathwayBrowser/#/R-RNO-190413 Autocatalytic phosphorylation of FGFR2c IEA Rattus norvegicus 30616 R-RNO-190427 https://reactome.org/PathwayBrowser/#/R-RNO-190427 Autocatalytic phosphorylation of FGFR1b IEA Rattus norvegicus 30616 R-RNO-190429 https://reactome.org/PathwayBrowser/#/R-RNO-190429 Autocatalytic phosphorylation of FGFR1c IEA Rattus norvegicus 30616 R-RNO-191062 https://reactome.org/PathwayBrowser/#/R-RNO-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Rattus norvegicus 30616 R-RNO-191380 https://reactome.org/PathwayBrowser/#/R-RNO-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Rattus norvegicus 30616 R-RNO-191414 https://reactome.org/PathwayBrowser/#/R-RNO-191414 MVD decarboxylates MVA5PP to IPPP IEA Rattus norvegicus 30616 R-RNO-191422 https://reactome.org/PathwayBrowser/#/R-RNO-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Rattus norvegicus 30616 R-RNO-191636 https://reactome.org/PathwayBrowser/#/R-RNO-191636 Phosphorylation of Cx43 by c-src IEA Rattus norvegicus 30616 R-RNO-192137 https://reactome.org/PathwayBrowser/#/R-RNO-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 30616 R-RNO-193362 https://reactome.org/PathwayBrowser/#/R-RNO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-193401 https://reactome.org/PathwayBrowser/#/R-RNO-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 30616 R-RNO-193407 https://reactome.org/PathwayBrowser/#/R-RNO-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 30616 R-RNO-193424 https://reactome.org/PathwayBrowser/#/R-RNO-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 30616 R-RNO-193703 https://reactome.org/PathwayBrowser/#/R-RNO-193703 IKKbeta is activated IEA Rattus norvegicus 30616 R-RNO-193711 https://reactome.org/PathwayBrowser/#/R-RNO-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 30616 R-RNO-193727 https://reactome.org/PathwayBrowser/#/R-RNO-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 30616 R-RNO-193743 https://reactome.org/PathwayBrowser/#/R-RNO-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 30616 R-RNO-193766 https://reactome.org/PathwayBrowser/#/R-RNO-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 30616 R-RNO-193887 https://reactome.org/PathwayBrowser/#/R-RNO-193887 Irak is activated TAS Rattus norvegicus 30616 R-RNO-194153 https://reactome.org/PathwayBrowser/#/R-RNO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-195275 https://reactome.org/PathwayBrowser/#/R-RNO-195275 Phosphorylation of APC component of the destruction complex IEA Rattus norvegicus 30616 R-RNO-195283 https://reactome.org/PathwayBrowser/#/R-RNO-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Rattus norvegicus 30616 R-RNO-195287 https://reactome.org/PathwayBrowser/#/R-RNO-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Rattus norvegicus 30616 R-RNO-195300 https://reactome.org/PathwayBrowser/#/R-RNO-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Rattus norvegicus 30616 R-RNO-195318 https://reactome.org/PathwayBrowser/#/R-RNO-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Rattus norvegicus 30616 R-RNO-1963581 https://reactome.org/PathwayBrowser/#/R-RNO-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Rattus norvegicus 30616 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 30616 R-RNO-1963586 https://reactome.org/PathwayBrowser/#/R-RNO-1963586 SRC family kinases phosphorylate ERBB2 IEA Rattus norvegicus 30616 R-RNO-196753 https://reactome.org/PathwayBrowser/#/R-RNO-196753 2xPPCS ligates PPanK with Cys IEA Rattus norvegicus 30616 R-RNO-196754 https://reactome.org/PathwayBrowser/#/R-RNO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Rattus norvegicus 30616 R-RNO-196761 https://reactome.org/PathwayBrowser/#/R-RNO-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Rattus norvegicus 30616 R-RNO-196773 https://reactome.org/PathwayBrowser/#/R-RNO-196773 COASY phosphorylates DP-CoA IEA Rattus norvegicus 30616 R-RNO-196857 https://reactome.org/PathwayBrowser/#/R-RNO-196857 PANK2 phosphorylates PanK IEA Rattus norvegicus 30616 R-RNO-196929 https://reactome.org/PathwayBrowser/#/R-RNO-196929 FLAD1 phosphorylates FMN IEA Rattus norvegicus 30616 R-RNO-196964 https://reactome.org/PathwayBrowser/#/R-RNO-196964 RFK:Mg2+ phosphorylates RIB IEA Rattus norvegicus 30616 R-RNO-197198 https://reactome.org/PathwayBrowser/#/R-RNO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 30616 R-RNO-197235 https://reactome.org/PathwayBrowser/#/R-RNO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 30616 R-RNO-197271 https://reactome.org/PathwayBrowser/#/R-RNO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Rattus norvegicus 30616 R-RNO-197958 https://reactome.org/PathwayBrowser/#/R-RNO-197958 FPGS-2 transforms THF to THFPG IEA Rattus norvegicus 30616 R-RNO-198266 https://reactome.org/PathwayBrowser/#/R-RNO-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Rattus norvegicus 30616 R-RNO-198314 https://reactome.org/PathwayBrowser/#/R-RNO-198314 DAG stimulates protein kinase C-delta IEA Rattus norvegicus 30616 R-RNO-198599 https://reactome.org/PathwayBrowser/#/R-RNO-198599 AKT phosphorylates MDM2 IEA Rattus norvegicus 30616 R-RNO-198601 https://reactome.org/PathwayBrowser/#/R-RNO-198601 Akt1 phosphorylates GSK3 TAS Rattus norvegicus 30616 R-RNO-198609 https://reactome.org/PathwayBrowser/#/R-RNO-198609 AKT phosphorylates TSC2, inhibiting it IEA Rattus norvegicus 30616 R-RNO-198611 https://reactome.org/PathwayBrowser/#/R-RNO-198611 AKT phosphorylates IKKalpha IEA Rattus norvegicus 30616 R-RNO-198613 https://reactome.org/PathwayBrowser/#/R-RNO-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Rattus norvegicus 30616 R-RNO-198621 https://reactome.org/PathwayBrowser/#/R-RNO-198621 AKT phosphorylates caspase-9 IEA Rattus norvegicus 30616 R-RNO-198640 https://reactome.org/PathwayBrowser/#/R-RNO-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Rattus norvegicus 30616 R-RNO-198669 https://reactome.org/PathwayBrowser/#/R-RNO-198669 p38MAPK phosphorylates MSK1 IEA Rattus norvegicus 30616 R-RNO-198717 https://reactome.org/PathwayBrowser/#/R-RNO-198717 STAT3 activation TAS Rattus norvegicus 30616 R-RNO-198739 https://reactome.org/PathwayBrowser/#/R-RNO-198739 ERK5 is activated TAS Rattus norvegicus 30616 R-RNO-198746 https://reactome.org/PathwayBrowser/#/R-RNO-198746 ERK1/2/5 activate RSK1/2/3 IEA Rattus norvegicus 30616 R-RNO-198756 https://reactome.org/PathwayBrowser/#/R-RNO-198756 ERK1/2 phosphorylates MSK1 IEA Rattus norvegicus 30616 R-RNO-199203 https://reactome.org/PathwayBrowser/#/R-RNO-199203 PANK1/3 phosphorylate PanK IEA Rattus norvegicus 30616 R-RNO-199298 https://reactome.org/PathwayBrowser/#/R-RNO-199298 AKT phosphorylates CREB1 IEA Rattus norvegicus 30616 R-RNO-199299 https://reactome.org/PathwayBrowser/#/R-RNO-199299 AKT phosphorylates FOXO transcription factors IEA Rattus norvegicus 30616 R-RNO-199839 https://reactome.org/PathwayBrowser/#/R-RNO-199839 AKT can phosphorylate RSK IEA Rattus norvegicus 30616 R-RNO-199863 https://reactome.org/PathwayBrowser/#/R-RNO-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Rattus norvegicus 30616 R-RNO-199895 https://reactome.org/PathwayBrowser/#/R-RNO-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Rattus norvegicus 30616 R-RNO-199910 https://reactome.org/PathwayBrowser/#/R-RNO-199910 MSK1 activates ATF1 IEA Rattus norvegicus 30616 R-RNO-199913 https://reactome.org/PathwayBrowser/#/R-RNO-199913 ERK5 activates the transcription factor MEF2 TAS Rattus norvegicus 30616 R-RNO-199917 https://reactome.org/PathwayBrowser/#/R-RNO-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Rattus norvegicus 30616 R-RNO-199935 https://reactome.org/PathwayBrowser/#/R-RNO-199935 MSK1 activates CREB IEA Rattus norvegicus 30616 R-RNO-200143 https://reactome.org/PathwayBrowser/#/R-RNO-200143 AKT phosphorylates AKT1S1 (PRAS40) IEA Rattus norvegicus 30616 R-RNO-200318 https://reactome.org/PathwayBrowser/#/R-RNO-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Rattus norvegicus 30616 R-RNO-200326 https://reactome.org/PathwayBrowser/#/R-RNO-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Rattus norvegicus 30616 R-RNO-200421 https://reactome.org/PathwayBrowser/#/R-RNO-200421 Activation of cytosolic AMPK by phosphorylation IEA Rattus norvegicus 30616 R-RNO-200423 https://reactome.org/PathwayBrowser/#/R-RNO-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Rattus norvegicus 30616 R-RNO-200474 https://reactome.org/PathwayBrowser/#/R-RNO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 30616 R-RNO-200512 https://reactome.org/PathwayBrowser/#/R-RNO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 30616 R-RNO-200555 https://reactome.org/PathwayBrowser/#/R-RNO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Rattus norvegicus 30616 R-RNO-200681 https://reactome.org/PathwayBrowser/#/R-RNO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Rattus norvegicus 30616 R-RNO-200682 https://reactome.org/PathwayBrowser/#/R-RNO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Rattus norvegicus 30616 R-RNO-200711 https://reactome.org/PathwayBrowser/#/R-RNO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Rattus norvegicus 30616 R-RNO-201035 https://reactome.org/PathwayBrowser/#/R-RNO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Rattus norvegicus 30616 R-RNO-201443 https://reactome.org/PathwayBrowser/#/R-RNO-201443 Type II receptor phosphorylates type I receptor IEA Rattus norvegicus 30616 R-RNO-201476 https://reactome.org/PathwayBrowser/#/R-RNO-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Rattus norvegicus 30616 R-RNO-201510 https://reactome.org/PathwayBrowser/#/R-RNO-201510 PI3K synthesizes PIP3 downstream of ALK IEA Rattus norvegicus 30616 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 30616 R-RNO-201677 https://reactome.org/PathwayBrowser/#/R-RNO-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Rattus norvegicus 30616 R-RNO-201717 https://reactome.org/PathwayBrowser/#/R-RNO-201717 CSNK2-mediated phosphorylation of DVL IEA Rattus norvegicus 30616 R-RNO-202111 https://reactome.org/PathwayBrowser/#/R-RNO-202111 AKT1 phosphorylates eNOS IEA Rattus norvegicus 30616 R-RNO-202165 https://reactome.org/PathwayBrowser/#/R-RNO-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Rattus norvegicus 30616 R-RNO-202168 https://reactome.org/PathwayBrowser/#/R-RNO-202168 Phosphorylation of ZAP-70 by Lck IEA Rattus norvegicus 30616 R-RNO-202174 https://reactome.org/PathwayBrowser/#/R-RNO-202174 Activation of ZAP-70 IEA Rattus norvegicus 30616 R-RNO-202216 https://reactome.org/PathwayBrowser/#/R-RNO-202216 Phosphorylation of SLP-76 IEA Rattus norvegicus 30616 R-RNO-202222 https://reactome.org/PathwayBrowser/#/R-RNO-202222 Phosphorylation of PKC theta IEA Rattus norvegicus 30616 R-RNO-202233 https://reactome.org/PathwayBrowser/#/R-RNO-202233 Inactivation of Lck by Csk IEA Rattus norvegicus 30616 R-RNO-202245 https://reactome.org/PathwayBrowser/#/R-RNO-202245 Phosphorylation of TBSMs in LAT IEA Rattus norvegicus 30616 R-RNO-202248 https://reactome.org/PathwayBrowser/#/R-RNO-202248 Phosphorylation of PLC-gamma1 IEA Rattus norvegicus 30616 R-RNO-202291 https://reactome.org/PathwayBrowser/#/R-RNO-202291 Activation of Lck IEA Rattus norvegicus 30616 R-RNO-202307 https://reactome.org/PathwayBrowser/#/R-RNO-202307 Change of PKC theta conformation IEA Rattus norvegicus 30616 R-RNO-202365 https://reactome.org/PathwayBrowser/#/R-RNO-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-202437 https://reactome.org/PathwayBrowser/#/R-RNO-202437 Phosphorylation of CARMA1 IEA Rattus norvegicus 30616 R-RNO-202459 https://reactome.org/PathwayBrowser/#/R-RNO-202459 Phosphorylation of Bcl10 IEA Rattus norvegicus 30616 R-RNO-202500 https://reactome.org/PathwayBrowser/#/R-RNO-202500 Activation of IKK complex IEA Rattus norvegicus 30616 R-RNO-202510 https://reactome.org/PathwayBrowser/#/R-RNO-202510 Activation of TAK1-TAB2 complex IEA Rattus norvegicus 30616 R-RNO-2028284 https://reactome.org/PathwayBrowser/#/R-RNO-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Rattus norvegicus 30616 R-RNO-2028555 https://reactome.org/PathwayBrowser/#/R-RNO-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Rattus norvegicus 30616 R-RNO-2028583 https://reactome.org/PathwayBrowser/#/R-RNO-2028583 Phosphorylation of YAP by LATS2 IEA Rattus norvegicus 30616 R-RNO-2028589 https://reactome.org/PathwayBrowser/#/R-RNO-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Rattus norvegicus 30616 R-RNO-2028591 https://reactome.org/PathwayBrowser/#/R-RNO-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Rattus norvegicus 30616 R-RNO-2028598 https://reactome.org/PathwayBrowser/#/R-RNO-2028598 Phosphorylation of YAP by LATS1 IEA Rattus norvegicus 30616 R-RNO-2028629 https://reactome.org/PathwayBrowser/#/R-RNO-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Rattus norvegicus 30616 R-RNO-2028635 https://reactome.org/PathwayBrowser/#/R-RNO-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Rattus norvegicus 30616 R-RNO-2028661 https://reactome.org/PathwayBrowser/#/R-RNO-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Rattus norvegicus 30616 R-RNO-2028670 https://reactome.org/PathwayBrowser/#/R-RNO-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Rattus norvegicus 30616 R-RNO-2028673 https://reactome.org/PathwayBrowser/#/R-RNO-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Rattus norvegicus 30616 R-RNO-2028675 https://reactome.org/PathwayBrowser/#/R-RNO-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Rattus norvegicus 30616 R-RNO-2028679 https://reactome.org/PathwayBrowser/#/R-RNO-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Rattus norvegicus 30616 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus 30616 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus 30616 R-RNO-2029454 https://reactome.org/PathwayBrowser/#/R-RNO-2029454 Autophosphorylation of PAK1 IEA Rattus norvegicus 30616 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus 30616 R-RNO-2029460 https://reactome.org/PathwayBrowser/#/R-RNO-2029460 PAK1 phosphorylates LIMK1 IEA Rattus norvegicus 30616 R-RNO-2029466 https://reactome.org/PathwayBrowser/#/R-RNO-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Rattus norvegicus 30616 R-RNO-2029469 https://reactome.org/PathwayBrowser/#/R-RNO-2029469 p-ERK phosphorylates WAVEs and ABI IEA Rattus norvegicus 30616 R-RNO-2029473 https://reactome.org/PathwayBrowser/#/R-RNO-2029473 Branching and elongation of mother and daughter filaments IEA Rattus norvegicus 30616 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus 30616 R-RNO-203070 https://reactome.org/PathwayBrowser/#/R-RNO-203070 Association of profilin with monomeric actin IEA Rattus norvegicus 30616 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 30616 R-RNO-2046085 https://reactome.org/PathwayBrowser/#/R-RNO-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Rattus norvegicus 30616 R-RNO-2046087 https://reactome.org/PathwayBrowser/#/R-RNO-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Rattus norvegicus 30616 R-RNO-2046093 https://reactome.org/PathwayBrowser/#/R-RNO-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Rattus norvegicus 30616 R-RNO-2046098 https://reactome.org/PathwayBrowser/#/R-RNO-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Rattus norvegicus 30616 R-RNO-205027 https://reactome.org/PathwayBrowser/#/R-RNO-205027 Nrage activates Jnk1 TAS Rattus norvegicus 30616 R-RNO-205075 https://reactome.org/PathwayBrowser/#/R-RNO-205075 JNK phosphorylates BIM, BAD and other targets IEA Rattus norvegicus 30616 R-RNO-205136 https://reactome.org/PathwayBrowser/#/R-RNO-205136 GTP-bound RAC contributes to JNK activation IEA Rattus norvegicus 30616 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 30616 R-RNO-2054095 https://reactome.org/PathwayBrowser/#/R-RNO-2054095 Phosphorylation of syk TAS Rattus norvegicus 30616 R-RNO-2060328 https://reactome.org/PathwayBrowser/#/R-RNO-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Rattus norvegicus 30616 R-RNO-209087 https://reactome.org/PathwayBrowser/#/R-RNO-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Rattus norvegicus 30616 R-RNO-210291 https://reactome.org/PathwayBrowser/#/R-RNO-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Rattus norvegicus 30616 R-RNO-211164 https://reactome.org/PathwayBrowser/#/R-RNO-211164 AKT phosphorylates FOXO1A IEA Rattus norvegicus 30616 R-RNO-212710 https://reactome.org/PathwayBrowser/#/R-RNO-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Rattus norvegicus 30616 R-RNO-2130194 https://reactome.org/PathwayBrowser/#/R-RNO-2130194 ABL phosphorylates WAVEs IEA Rattus norvegicus 30616 R-RNO-2162084 https://reactome.org/PathwayBrowser/#/R-RNO-2162084 carbovir diphosphate + ATP => carbovir triphosphate + ADP TAS Rattus norvegicus 30616 R-RNO-216723 https://reactome.org/PathwayBrowser/#/R-RNO-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 30616 R-RNO-216757 https://reactome.org/PathwayBrowser/#/R-RNO-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 30616 R-RNO-2168079 https://reactome.org/PathwayBrowser/#/R-RNO-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Rattus norvegicus 30616 R-RNO-2176475 https://reactome.org/PathwayBrowser/#/R-RNO-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Rattus norvegicus 30616 R-RNO-2197690 https://reactome.org/PathwayBrowser/#/R-RNO-2197690 Detachment of WASP/WAVE IEA Rattus norvegicus 30616 R-RNO-2197698 https://reactome.org/PathwayBrowser/#/R-RNO-2197698 Src phosphorylate WASP,N-WASP IEA Rattus norvegicus 30616 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus 30616 R-RNO-2214351 https://reactome.org/PathwayBrowser/#/R-RNO-2214351 PLK1 phosphorylates GORASP1 IEA Rattus norvegicus 30616 R-RNO-2267372 https://reactome.org/PathwayBrowser/#/R-RNO-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Rattus norvegicus 30616 R-RNO-2294580 https://reactome.org/PathwayBrowser/#/R-RNO-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Rattus norvegicus 30616 R-RNO-2294600 https://reactome.org/PathwayBrowser/#/R-RNO-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Rattus norvegicus 30616 R-RNO-2316434 https://reactome.org/PathwayBrowser/#/R-RNO-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-2395412 https://reactome.org/PathwayBrowser/#/R-RNO-2395412 Phosphorylation of SYK IEA Rattus norvegicus 30616 R-RNO-2395801 https://reactome.org/PathwayBrowser/#/R-RNO-2395801 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus 30616 R-RNO-2396002 https://reactome.org/PathwayBrowser/#/R-RNO-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex IEA Rattus norvegicus 30616 R-RNO-2396007 https://reactome.org/PathwayBrowser/#/R-RNO-2396007 IRF3 is phosphorylated by TBK1 IEA Rattus norvegicus 30616 R-RNO-2396594 https://reactome.org/PathwayBrowser/#/R-RNO-2396594 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus 30616 R-RNO-2404193 https://reactome.org/PathwayBrowser/#/R-RNO-2404193 IGF1R phosphorylates SHC1 IEA Rattus norvegicus 30616 R-RNO-2404199 https://reactome.org/PathwayBrowser/#/R-RNO-2404199 IGF1,2:IGF1R autophosphorylates IEA Rattus norvegicus 30616 R-RNO-2408504 https://reactome.org/PathwayBrowser/#/R-RNO-2408504 H2SeO4 is converted to APSe by PAPSS1,2 TAS Rattus norvegicus 30616 R-RNO-2408551 https://reactome.org/PathwayBrowser/#/R-RNO-2408551 SeMet is converted to AdoSeMet by MAT IEA Rattus norvegicus 30616 R-RNO-2422927 https://reactome.org/PathwayBrowser/#/R-RNO-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Rattus norvegicus 30616 R-RNO-2424480 https://reactome.org/PathwayBrowser/#/R-RNO-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-2424484 https://reactome.org/PathwayBrowser/#/R-RNO-2424484 Phosphorylation of BTK by p-SYK IEA Rattus norvegicus 30616 R-RNO-2424486 https://reactome.org/PathwayBrowser/#/R-RNO-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Rattus norvegicus 30616 R-RNO-2424487 https://reactome.org/PathwayBrowser/#/R-RNO-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Rattus norvegicus 30616 R-RNO-2428926 https://reactome.org/PathwayBrowser/#/R-RNO-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Rattus norvegicus 30616 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus 30616 R-RNO-2466068 https://reactome.org/PathwayBrowser/#/R-RNO-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Rattus norvegicus 30616 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus 30616 R-RNO-2468293 https://reactome.org/PathwayBrowser/#/R-RNO-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Rattus norvegicus 30616 R-RNO-2529020 https://reactome.org/PathwayBrowser/#/R-RNO-2529020 CK2 phosphorylates condensin I subunits IEA Rattus norvegicus 30616 R-RNO-2562526 https://reactome.org/PathwayBrowser/#/R-RNO-2562526 PLK1 phosphorylates OPTN IEA Rattus norvegicus 30616 R-RNO-2574840 https://reactome.org/PathwayBrowser/#/R-RNO-2574840 AJUBA facilitates AURKA autophosphorylation IEA Rattus norvegicus 30616 R-RNO-2581474 https://reactome.org/PathwayBrowser/#/R-RNO-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Rattus norvegicus 30616 R-RNO-265682 https://reactome.org/PathwayBrowser/#/R-RNO-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Rattus norvegicus 30616 R-RNO-265783 https://reactome.org/PathwayBrowser/#/R-RNO-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-266082 https://reactome.org/PathwayBrowser/#/R-RNO-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Rattus norvegicus 30616 R-RNO-2682349 https://reactome.org/PathwayBrowser/#/R-RNO-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Rattus norvegicus 30616 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus 30616 R-RNO-2730835 https://reactome.org/PathwayBrowser/#/R-RNO-2730835 Autophosphorylation of PKC-theta IEA Rattus norvegicus 30616 R-RNO-2730841 https://reactome.org/PathwayBrowser/#/R-RNO-2730841 Phosphorylation and activation of VAV IEA Rattus norvegicus 30616 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus 30616 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus 30616 R-RNO-2730856 https://reactome.org/PathwayBrowser/#/R-RNO-2730856 Autophosphorylation of PAK IEA Rattus norvegicus 30616 R-RNO-2730858 https://reactome.org/PathwayBrowser/#/R-RNO-2730858 Autophosphorylation of BTK/ITK IEA Rattus norvegicus 30616 R-RNO-2730862 https://reactome.org/PathwayBrowser/#/R-RNO-2730862 Autophosphorylation of LYN kinase IEA Rattus norvegicus 30616 R-RNO-2730863 https://reactome.org/PathwayBrowser/#/R-RNO-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Rattus norvegicus 30616 R-RNO-2730868 https://reactome.org/PathwayBrowser/#/R-RNO-2730868 Phosphorylation of MEK7 by MEKK1 IEA Rattus norvegicus 30616 R-RNO-2730870 https://reactome.org/PathwayBrowser/#/R-RNO-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Rattus norvegicus 30616 R-RNO-2730876 https://reactome.org/PathwayBrowser/#/R-RNO-2730876 Phosphorylation of IKK-beta by TAK1 IEA Rattus norvegicus 30616 R-RNO-2730881 https://reactome.org/PathwayBrowser/#/R-RNO-2730881 Phosphorylation of PLC-gamma TAS Rattus norvegicus 30616 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus 30616 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus 30616 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus 30616 R-RNO-2730896 https://reactome.org/PathwayBrowser/#/R-RNO-2730896 Phosphorylation of MEK4 by MEKK1 IEA Rattus norvegicus 30616 R-RNO-2730900 https://reactome.org/PathwayBrowser/#/R-RNO-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Rattus norvegicus 30616 R-RNO-2855020 https://reactome.org/PathwayBrowser/#/R-RNO-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Rattus norvegicus 30616 R-RNO-2984220 https://reactome.org/PathwayBrowser/#/R-RNO-2984220 CDK1:CCNB phosphorylates NEK9 IEA Rattus norvegicus 30616 R-RNO-2984226 https://reactome.org/PathwayBrowser/#/R-RNO-2984226 PLK1 phosphorylates NEK9 IEA Rattus norvegicus 30616 R-RNO-2990833 https://reactome.org/PathwayBrowser/#/R-RNO-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Rattus norvegicus 30616 R-RNO-2990882 https://reactome.org/PathwayBrowser/#/R-RNO-2990882 CDK1 phosphorylates NUP98 IEA Rattus norvegicus 30616 R-RNO-2993447 https://reactome.org/PathwayBrowser/#/R-RNO-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Rattus norvegicus 30616 R-RNO-2993799 https://reactome.org/PathwayBrowser/#/R-RNO-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Rattus norvegicus 30616 R-RNO-2993802 https://reactome.org/PathwayBrowser/#/R-RNO-2993802 HLCS biotinylates PC:Mn2+ IEA Rattus norvegicus 30616 R-RNO-2993814 https://reactome.org/PathwayBrowser/#/R-RNO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Rattus norvegicus 30616 R-RNO-2993898 https://reactome.org/PathwayBrowser/#/R-RNO-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Rattus norvegicus 30616 R-RNO-3000310 https://reactome.org/PathwayBrowser/#/R-RNO-3000310 AURKA phosphorylates PLK1 IEA Rattus norvegicus 30616 R-RNO-3000327 https://reactome.org/PathwayBrowser/#/R-RNO-3000327 PLK1 phosphorylates BORA IEA Rattus norvegicus 30616 R-RNO-3095901 https://reactome.org/PathwayBrowser/#/R-RNO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Rattus norvegicus 30616 R-RNO-3132737 https://reactome.org/PathwayBrowser/#/R-RNO-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Rattus norvegicus 30616 R-RNO-3159253 https://reactome.org/PathwayBrowser/#/R-RNO-3159253 MMAB adenosylates cob(I)alamin IEA Rattus norvegicus 30616 R-RNO-3222006 https://reactome.org/PathwayBrowser/#/R-RNO-3222006 STK11 (LKB1) phosphorylates NUAK1 IEA Rattus norvegicus 30616 R-RNO-3222020 https://reactome.org/PathwayBrowser/#/R-RNO-3222020 NUAK1 phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-3228469 https://reactome.org/PathwayBrowser/#/R-RNO-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Rattus norvegicus 30616 R-RNO-3229102 https://reactome.org/PathwayBrowser/#/R-RNO-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Rattus norvegicus 30616 R-RNO-3238999 https://reactome.org/PathwayBrowser/#/R-RNO-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Rattus norvegicus 30616 R-RNO-3239014 https://reactome.org/PathwayBrowser/#/R-RNO-3239014 MAPKAPK5 phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-3239019 https://reactome.org/PathwayBrowser/#/R-RNO-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Rattus norvegicus 30616 R-RNO-3249371 https://reactome.org/PathwayBrowser/#/R-RNO-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Rattus norvegicus 30616 R-RNO-3249379 https://reactome.org/PathwayBrowser/#/R-RNO-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Rattus norvegicus 30616 R-RNO-3249390 https://reactome.org/PathwayBrowser/#/R-RNO-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Rattus norvegicus 30616 R-RNO-3371422 https://reactome.org/PathwayBrowser/#/R-RNO-3371422 ATP hydrolysis by HSP70 IEA Rattus norvegicus 30616 R-RNO-3371435 https://reactome.org/PathwayBrowser/#/R-RNO-3371435 Constitutive phosphorylation by GSK3 IEA Rattus norvegicus 30616 R-RNO-3371531 https://reactome.org/PathwayBrowser/#/R-RNO-3371531 Constitutive phosphorylation by pERK1/2 IEA Rattus norvegicus 30616 R-RNO-3371590 https://reactome.org/PathwayBrowser/#/R-RNO-3371590 HSP70 binds to HSP40:nascent protein IEA Rattus norvegicus 30616 R-RNO-349426 https://reactome.org/PathwayBrowser/#/R-RNO-349426 Phosphorylation of MDM4 by CHEK2 IEA Rattus norvegicus 30616 R-RNO-349444 https://reactome.org/PathwayBrowser/#/R-RNO-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Rattus norvegicus 30616 R-RNO-349455 https://reactome.org/PathwayBrowser/#/R-RNO-349455 Phosphorylation of MDM4 by ATM IEA Rattus norvegicus 30616 R-RNO-354073 https://reactome.org/PathwayBrowser/#/R-RNO-354073 Autophosphorylation of PTK2 at Y397 IEA Rattus norvegicus 30616 R-RNO-354124 https://reactome.org/PathwayBrowser/#/R-RNO-354124 Phosphorylation of pPTK2 by SRC IEA Rattus norvegicus 30616 R-RNO-372693 https://reactome.org/PathwayBrowser/#/R-RNO-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Rattus norvegicus 30616 R-RNO-373735 https://reactome.org/PathwayBrowser/#/R-RNO-373735 Shootin-1 links L1 and retrograde actin flow TAS Rattus norvegicus 30616 R-RNO-373747 https://reactome.org/PathwayBrowser/#/R-RNO-373747 Phosphorylation of nephrin by FYN IEA Rattus norvegicus 30616 R-RNO-373750 https://reactome.org/PathwayBrowser/#/R-RNO-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Rattus norvegicus 30616 R-RNO-374664 https://reactome.org/PathwayBrowser/#/R-RNO-374664 Phosphorylation and activation of Ezrin IEA Rattus norvegicus 30616 R-RNO-374701 https://reactome.org/PathwayBrowser/#/R-RNO-374701 Phosphorylation of DCC by Fyn IEA Rattus norvegicus 30616 R-RNO-375160 https://reactome.org/PathwayBrowser/#/R-RNO-375160 NCAM1 binds to ATP IEA Rattus norvegicus 30616 R-RNO-3769394 https://reactome.org/PathwayBrowser/#/R-RNO-3769394 AKT phosphorylates CBY1 IEA Rattus norvegicus 30616 R-RNO-377186 https://reactome.org/PathwayBrowser/#/R-RNO-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Rattus norvegicus 30616 R-RNO-3772435 https://reactome.org/PathwayBrowser/#/R-RNO-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Rattus norvegicus 30616 R-RNO-3772436 https://reactome.org/PathwayBrowser/#/R-RNO-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Rattus norvegicus 30616 R-RNO-377640 https://reactome.org/PathwayBrowser/#/R-RNO-377640 Autophosphorylation of SRC IEA Rattus norvegicus 30616 R-RNO-3788705 https://reactome.org/PathwayBrowser/#/R-RNO-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Rattus norvegicus 30616 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 30616 R-RNO-379832 https://reactome.org/PathwayBrowser/#/R-RNO-379832 CaMKIV phosphorylates Creb1 TAS Rattus norvegicus 30616 R-RNO-380272 https://reactome.org/PathwayBrowser/#/R-RNO-380272 Plk1-mediated phosphorylation of Nlp IEA Rattus norvegicus 30616 R-RNO-380278 https://reactome.org/PathwayBrowser/#/R-RNO-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Rattus norvegicus 30616 R-RNO-380780 https://reactome.org/PathwayBrowser/#/R-RNO-380780 Activation of Src IEA Rattus norvegicus 30616 R-RNO-380927 https://reactome.org/PathwayBrowser/#/R-RNO-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Rattus norvegicus 30616 R-RNO-381091 https://reactome.org/PathwayBrowser/#/R-RNO-381091 IRE1 dimer autophosphorylates IEA Rattus norvegicus 30616 R-RNO-381111 https://reactome.org/PathwayBrowser/#/R-RNO-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Rattus norvegicus 30616 R-RNO-382553 https://reactome.org/PathwayBrowser/#/R-RNO-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Rattus norvegicus 30616 R-RNO-382560 https://reactome.org/PathwayBrowser/#/R-RNO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Rattus norvegicus 30616 R-RNO-382575 https://reactome.org/PathwayBrowser/#/R-RNO-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Rattus norvegicus 30616 R-RNO-383190 https://reactome.org/PathwayBrowser/#/R-RNO-383190 HCO3- transport through ion channel IEA Rattus norvegicus 30616 R-RNO-3857329 https://reactome.org/PathwayBrowser/#/R-RNO-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Rattus norvegicus 30616 R-RNO-388831 https://reactome.org/PathwayBrowser/#/R-RNO-388831 Phosphorylation of CD28 IEA Rattus norvegicus 30616 R-RNO-388833 https://reactome.org/PathwayBrowser/#/R-RNO-388833 Phosphorylation of CTLA-4 IEA Rattus norvegicus 30616 R-RNO-389083 https://reactome.org/PathwayBrowser/#/R-RNO-389083 Autophosphorylation of PDGF alpha receptors IEA Rattus norvegicus 30616 R-RNO-389086 https://reactome.org/PathwayBrowser/#/R-RNO-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Rattus norvegicus 30616 R-RNO-389158 https://reactome.org/PathwayBrowser/#/R-RNO-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-389354 https://reactome.org/PathwayBrowser/#/R-RNO-389354 Activation of Vav1 IEA Rattus norvegicus 30616 R-RNO-389622 https://reactome.org/PathwayBrowser/#/R-RNO-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 30616 R-RNO-389632 https://reactome.org/PathwayBrowser/#/R-RNO-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 30616 R-RNO-389756 https://reactome.org/PathwayBrowser/#/R-RNO-389756 AKT interacts and phosphorylates Cot IEA Rattus norvegicus 30616 R-RNO-389762 https://reactome.org/PathwayBrowser/#/R-RNO-389762 Phosphorylation of PD-1 IEA Rattus norvegicus 30616 R-RNO-390593 https://reactome.org/PathwayBrowser/#/R-RNO-390593 ATP Hydrolysis By Myosin IEA Rattus norvegicus 30616 R-RNO-390598 https://reactome.org/PathwayBrowser/#/R-RNO-390598 Myosin Binds ATP IEA Rattus norvegicus 30616 R-RNO-392300 https://reactome.org/PathwayBrowser/#/R-RNO-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-392530 https://reactome.org/PathwayBrowser/#/R-RNO-392530 p-S400-Cot phosphorylates NIK IEA Rattus norvegicus 30616 R-RNO-392751 https://reactome.org/PathwayBrowser/#/R-RNO-392751 L1 linked to actin cytoskeleton by ankyrin IEA Rattus norvegicus 30616 R-RNO-392752 https://reactome.org/PathwayBrowser/#/R-RNO-392752 Phosphorylation of L1 by CK-II IEA Rattus norvegicus 30616 R-RNO-3928578 https://reactome.org/PathwayBrowser/#/R-RNO-3928578 EPH receptors autophosphorylate IEA Rattus norvegicus 30616 R-RNO-3928595 https://reactome.org/PathwayBrowser/#/R-RNO-3928595 N-WASP binds ARP2/3 and G-actin IEA Rattus norvegicus 30616 R-RNO-3928604 https://reactome.org/PathwayBrowser/#/R-RNO-3928604 SFKs phosphorylate VAV2,3 IEA Rattus norvegicus 30616 R-RNO-3928620 https://reactome.org/PathwayBrowser/#/R-RNO-3928620 PAK1 autophosphorylates IEA Rattus norvegicus 30616 R-RNO-3928625 https://reactome.org/PathwayBrowser/#/R-RNO-3928625 PAKs autophosphorylate IEA Rattus norvegicus 30616 R-RNO-3928627 https://reactome.org/PathwayBrowser/#/R-RNO-3928627 EPHB phosphorylates TIAM1 IEA Rattus norvegicus 30616 R-RNO-3928640 https://reactome.org/PathwayBrowser/#/R-RNO-3928640 PAKs phosphorylate MLC IEA Rattus norvegicus 30616 R-RNO-399939 https://reactome.org/PathwayBrowser/#/R-RNO-399939 Autophosphorylation of PAK IEA Rattus norvegicus 30616 R-RNO-399944 https://reactome.org/PathwayBrowser/#/R-RNO-399944 Phosphorylation of CRMPs by Cdk5 IEA Rattus norvegicus 30616 R-RNO-399947 https://reactome.org/PathwayBrowser/#/R-RNO-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Rattus norvegicus 30616 R-RNO-399951 https://reactome.org/PathwayBrowser/#/R-RNO-399951 Phosphorylation of CRMPs by GSK3beta IEA Rattus norvegicus 30616 R-RNO-399952 https://reactome.org/PathwayBrowser/#/R-RNO-399952 Phosphorylation of LIMK-1 by PAK IEA Rattus norvegicus 30616 R-RNO-399978 https://reactome.org/PathwayBrowser/#/R-RNO-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Rattus norvegicus 30616 R-RNO-4085028 https://reactome.org/PathwayBrowser/#/R-RNO-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Rattus norvegicus 30616 R-RNO-4086410 https://reactome.org/PathwayBrowser/#/R-RNO-4086410 CDK1 phosphorylates BORA IEA Rattus norvegicus 30616 R-RNO-4088024 https://reactome.org/PathwayBrowser/#/R-RNO-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Rattus norvegicus 30616 R-RNO-4088134 https://reactome.org/PathwayBrowser/#/R-RNO-4088134 PLK1 phosphorylates FOXM1 IEA Rattus norvegicus 30616 R-RNO-4093332 https://reactome.org/PathwayBrowser/#/R-RNO-4093332 p-EPHB phosphorylates SDC2 IEA Rattus norvegicus 30616 R-RNO-416320 https://reactome.org/PathwayBrowser/#/R-RNO-416320 Trafficking of GluR1-containing AMPA receptors IEA Rattus norvegicus 30616 R-RNO-416639 https://reactome.org/PathwayBrowser/#/R-RNO-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Rattus norvegicus 30616 R-RNO-4167511 https://reactome.org/PathwayBrowser/#/R-RNO-4167511 HLCS biotinylates ACACB IEA Rattus norvegicus 30616 R-RNO-416985 https://reactome.org/PathwayBrowser/#/R-RNO-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Rattus norvegicus 30616 R-RNO-417927 https://reactome.org/PathwayBrowser/#/R-RNO-417927 P2Y2 receptor binds ATP and UTP IEA Rattus norvegicus 30616 R-RNO-418845 https://reactome.org/PathwayBrowser/#/R-RNO-418845 Activation of caspase-3 IEA Rattus norvegicus 30616 R-RNO-419490 https://reactome.org/PathwayBrowser/#/R-RNO-419490 Binding of ATP to P2X receptors IEA Rattus norvegicus 30616 R-RNO-419644 https://reactome.org/PathwayBrowser/#/R-RNO-419644 Transphosphorylation of pLIMK1 IEA Rattus norvegicus 30616 R-RNO-419646 https://reactome.org/PathwayBrowser/#/R-RNO-419646 SEMA4D interacts with Plexin-B1:Met IEA Rattus norvegicus 30616 R-RNO-421007 https://reactome.org/PathwayBrowser/#/R-RNO-421007 Endocytosis of Ca impermeable AMPA receptors IEA Rattus norvegicus 30616 R-RNO-421836 https://reactome.org/PathwayBrowser/#/R-RNO-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Rattus norvegicus 30616 R-RNO-426240 https://reactome.org/PathwayBrowser/#/R-RNO-426240 DAG kinase produces phosphatidic acid from DAG IEA Rattus norvegicus 30616 R-RNO-428273 https://reactome.org/PathwayBrowser/#/R-RNO-428273 SPHK1 phosphorylates sphingoid IEA Rattus norvegicus 30616 R-RNO-428941 https://reactome.org/PathwayBrowser/#/R-RNO-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Rattus norvegicus 30616 R-RNO-428961 https://reactome.org/PathwayBrowser/#/R-RNO-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Rattus norvegicus 30616 R-RNO-429016 https://reactome.org/PathwayBrowser/#/R-RNO-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Rattus norvegicus 30616 R-RNO-429157 https://reactome.org/PathwayBrowser/#/R-RNO-429157 ABCC4 accumulation of dense granule contents IEA Rattus norvegicus 30616 R-RNO-429441 https://reactome.org/PathwayBrowser/#/R-RNO-429441 SYK activation by SRC IEA Rattus norvegicus 30616 R-RNO-429449 https://reactome.org/PathwayBrowser/#/R-RNO-429449 Syk activation leads to SLP-76 activation IEA Rattus norvegicus 30616 R-RNO-430347 https://reactome.org/PathwayBrowser/#/R-RNO-430347 MigFilin associates with Filamin and F-actin IEA Rattus norvegicus 30616 R-RNO-432129 https://reactome.org/PathwayBrowser/#/R-RNO-432129 FGR binds and phosphorylates LRP8 IEA Rattus norvegicus 30616 R-RNO-432148 https://reactome.org/PathwayBrowser/#/R-RNO-432148 Fgr may phosphorylate p38 MAPK IEA Rattus norvegicus 30616 R-RNO-432232 https://reactome.org/PathwayBrowser/#/R-RNO-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Rattus norvegicus 30616 R-RNO-432688 https://reactome.org/PathwayBrowser/#/R-RNO-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating IEA Rattus norvegicus 30616 R-RNO-4332358 https://reactome.org/PathwayBrowser/#/R-RNO-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Rattus norvegicus 30616 R-RNO-4332363 https://reactome.org/PathwayBrowser/#/R-RNO-4332363 Autophosphorylation and activation of CAMK2 IEA Rattus norvegicus 30616 R-RNO-433717 https://reactome.org/PathwayBrowser/#/R-RNO-433717 Interaction of Afadin with F-actin TAS Rattus norvegicus 30616 R-RNO-434382 https://reactome.org/PathwayBrowser/#/R-RNO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Rattus norvegicus 30616 R-RNO-434836 https://reactome.org/PathwayBrowser/#/R-RNO-434836 Syk/Lck phosphorylate LAT IEA Rattus norvegicus 30616 R-RNO-435244 https://reactome.org/PathwayBrowser/#/R-RNO-435244 PECAM1 is phosphorylated IEA Rattus norvegicus 30616 R-RNO-437162 https://reactome.org/PathwayBrowser/#/R-RNO-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-437185 https://reactome.org/PathwayBrowser/#/R-RNO-437185 PDK1 activates PKC zeta TAS Rattus norvegicus 30616 R-RNO-4411383 https://reactome.org/PathwayBrowser/#/R-RNO-4411383 NLK phosphorylates TCF/LEF IEA Rattus norvegicus 30616 R-RNO-4411402 https://reactome.org/PathwayBrowser/#/R-RNO-4411402 Activation of NLK IEA Rattus norvegicus 30616 R-RNO-4420117 https://reactome.org/PathwayBrowser/#/R-RNO-4420117 VEGFR2 autophosphorylates IEA Rattus norvegicus 30616 R-RNO-4420121 https://reactome.org/PathwayBrowser/#/R-RNO-4420121 SFKs phosphorylate PLCG1 IEA Rattus norvegicus 30616 R-RNO-4420128 https://reactome.org/PathwayBrowser/#/R-RNO-4420128 SRC-1 phosphorylates SHB IEA Rattus norvegicus 30616 R-RNO-4420206 https://reactome.org/PathwayBrowser/#/R-RNO-4420206 Phosphorylation of SRC-1 IEA Rattus norvegicus 30616 R-RNO-442724 https://reactome.org/PathwayBrowser/#/R-RNO-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Rattus norvegicus 30616 R-RNO-442749 https://reactome.org/PathwayBrowser/#/R-RNO-442749 CaMKK autophosphorylates in the nucleus IEA Rattus norvegicus 30616 R-RNO-443779 https://reactome.org/PathwayBrowser/#/R-RNO-443779 Linkage of L1 with treadmilling F-actin IEA Rattus norvegicus 30616 R-RNO-445072 https://reactome.org/PathwayBrowser/#/R-RNO-445072 Interaction of PAK1 with Rac1-GTP IEA Rattus norvegicus 30616 R-RNO-445079 https://reactome.org/PathwayBrowser/#/R-RNO-445079 Phosphorylation of L1 by ERK IEA Rattus norvegicus 30616 R-RNO-445080 https://reactome.org/PathwayBrowser/#/R-RNO-445080 Phosphorylation of Neurofascin TAS Rattus norvegicus 30616 R-RNO-445084 https://reactome.org/PathwayBrowser/#/R-RNO-445084 Phosphorylation of L1 by SRC IEA Rattus norvegicus 30616 R-RNO-445700 https://reactome.org/PathwayBrowser/#/R-RNO-445700 Myosin Binds ATP IEA Rattus norvegicus 30616 R-RNO-445813 https://reactome.org/PathwayBrowser/#/R-RNO-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Rattus norvegicus 30616 R-RNO-446634 https://reactome.org/PathwayBrowser/#/R-RNO-446634 IRAK4 is activated by autophosphorylation IEA Rattus norvegicus 30616 R-RNO-446694 https://reactome.org/PathwayBrowser/#/R-RNO-446694 IRAK4 phosphorylates IRAK1 IEA Rattus norvegicus 30616 R-RNO-446701 https://reactome.org/PathwayBrowser/#/R-RNO-446701 IRAK4-activated IRAK1 autophosphorylates IEA Rattus norvegicus 30616 R-RNO-447074 https://reactome.org/PathwayBrowser/#/R-RNO-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Rattus norvegicus 30616 R-RNO-448955 https://reactome.org/PathwayBrowser/#/R-RNO-448955 Phosphorylation of MEF2 proteins by p38 IEA Rattus norvegicus 30616 R-RNO-449911 https://reactome.org/PathwayBrowser/#/R-RNO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Rattus norvegicus 30616 R-RNO-450088 https://reactome.org/PathwayBrowser/#/R-RNO-450088 GLUT1 tetramer binds 4xATP IEA Rattus norvegicus 30616 R-RNO-450092 https://reactome.org/PathwayBrowser/#/R-RNO-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Rattus norvegicus 30616 R-RNO-450222 https://reactome.org/PathwayBrowser/#/R-RNO-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Rattus norvegicus 30616 R-RNO-450325 https://reactome.org/PathwayBrowser/#/R-RNO-450325 c-FOS activation by phospho ERK1/2 IEA Rattus norvegicus 30616 R-RNO-450333 https://reactome.org/PathwayBrowser/#/R-RNO-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Rattus norvegicus 30616 R-RNO-450337 https://reactome.org/PathwayBrowser/#/R-RNO-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Rattus norvegicus 30616 R-RNO-450346 https://reactome.org/PathwayBrowser/#/R-RNO-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Rattus norvegicus 30616 R-RNO-450463 https://reactome.org/PathwayBrowser/#/R-RNO-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Rattus norvegicus 30616 R-RNO-450474 https://reactome.org/PathwayBrowser/#/R-RNO-450474 MK2 phosphorylates BRF1 IEA Rattus norvegicus 30616 R-RNO-450490 https://reactome.org/PathwayBrowser/#/R-RNO-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Rattus norvegicus 30616 R-RNO-450499 https://reactome.org/PathwayBrowser/#/R-RNO-450499 Protein Kinase B (AKT) phosphorylates KSRP IEA Rattus norvegicus 30616 R-RNO-450533 https://reactome.org/PathwayBrowser/#/R-RNO-450533 PKCdelta phosphorylates HuR IEA Rattus norvegicus 30616 R-RNO-450550 https://reactome.org/PathwayBrowser/#/R-RNO-450550 PKCalpha phosphorylates HuR IEA Rattus norvegicus 30616 R-RNO-450827 https://reactome.org/PathwayBrowser/#/R-RNO-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Rattus norvegicus 30616 R-RNO-451942 https://reactome.org/PathwayBrowser/#/R-RNO-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Rattus norvegicus 30616 R-RNO-452097 https://reactome.org/PathwayBrowser/#/R-RNO-452097 Recruited STAT5 is phosphorylated IEA Rattus norvegicus 30616 R-RNO-452100 https://reactome.org/PathwayBrowser/#/R-RNO-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Rattus norvegicus 30616 R-RNO-452122 https://reactome.org/PathwayBrowser/#/R-RNO-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Rattus norvegicus 30616 R-RNO-453200 https://reactome.org/PathwayBrowser/#/R-RNO-453200 SYK autophosphorylates IEA Rattus norvegicus 30616 R-RNO-453342 https://reactome.org/PathwayBrowser/#/R-RNO-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Rattus norvegicus 30616 R-RNO-4793911 https://reactome.org/PathwayBrowser/#/R-RNO-4793911 MAPKAPK2 phosphorylates HSF1 IEA Rattus norvegicus 30616 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 30616 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 30616 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 30616 R-RNO-504054 https://reactome.org/PathwayBrowser/#/R-RNO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Rattus norvegicus 30616 R-RNO-508040 https://reactome.org/PathwayBrowser/#/R-RNO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Rattus norvegicus 30616 R-RNO-5082387 https://reactome.org/PathwayBrowser/#/R-RNO-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Rattus norvegicus 30616 R-RNO-5082405 https://reactome.org/PathwayBrowser/#/R-RNO-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Rattus norvegicus 30616 R-RNO-508282 https://reactome.org/PathwayBrowser/#/R-RNO-508282 SYK is a substrate for JAK1 IEA Rattus norvegicus 30616 R-RNO-508308 https://reactome.org/PathwayBrowser/#/R-RNO-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Rattus norvegicus 30616 R-RNO-5138432 https://reactome.org/PathwayBrowser/#/R-RNO-5138432 DVL2 is phosphorylated by PKC IEA Rattus norvegicus 30616 R-RNO-5195402 https://reactome.org/PathwayBrowser/#/R-RNO-5195402 CDK1 phosphorylates LPIN IEA Rattus norvegicus 30616 R-RNO-5213464 https://reactome.org/PathwayBrowser/#/R-RNO-5213464 RIPK1 is phosphorylated IEA Rattus norvegicus 30616 R-RNO-5213466 https://reactome.org/PathwayBrowser/#/R-RNO-5213466 RIPK3 is phosphorylated IEA Rattus norvegicus 30616 R-RNO-5218640 https://reactome.org/PathwayBrowser/#/R-RNO-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Rattus norvegicus 30616 R-RNO-5218642 https://reactome.org/PathwayBrowser/#/R-RNO-5218642 PTK2 autophosphorylates IEA Rattus norvegicus 30616 R-RNO-5218804 https://reactome.org/PathwayBrowser/#/R-RNO-5218804 p38 MAPK activation by VEGFR IEA Rattus norvegicus 30616 R-RNO-5218805 https://reactome.org/PathwayBrowser/#/R-RNO-5218805 PKC autophosphorylates IEA Rattus norvegicus 30616 R-RNO-5218806 https://reactome.org/PathwayBrowser/#/R-RNO-5218806 FYN autophosphorylates IEA Rattus norvegicus 30616 R-RNO-5218809 https://reactome.org/PathwayBrowser/#/R-RNO-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Rattus norvegicus 30616 R-RNO-5218812 https://reactome.org/PathwayBrowser/#/R-RNO-5218812 FYN phosphorylates PAK2 IEA Rattus norvegicus 30616 R-RNO-5218814 https://reactome.org/PathwayBrowser/#/R-RNO-5218814 PAK2 autophorylates IEA Rattus norvegicus 30616 R-RNO-5218819 https://reactome.org/PathwayBrowser/#/R-RNO-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-5218820 https://reactome.org/PathwayBrowser/#/R-RNO-5218820 Src kinases phosphorylate VAV IEA Rattus norvegicus 30616 R-RNO-5218821 https://reactome.org/PathwayBrowser/#/R-RNO-5218821 PDK1 phosphorylates PKC IEA Rattus norvegicus 30616 R-RNO-5218823 https://reactome.org/PathwayBrowser/#/R-RNO-5218823 PKC phosphorylates sphingosine kinase 1 IEA Rattus norvegicus 30616 R-RNO-5218826 https://reactome.org/PathwayBrowser/#/R-RNO-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Rattus norvegicus 30616 R-RNO-5218830 https://reactome.org/PathwayBrowser/#/R-RNO-5218830 SRC-1 phosphorylates PTK2-beta IEA Rattus norvegicus 30616 R-RNO-5218845 https://reactome.org/PathwayBrowser/#/R-RNO-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Rattus norvegicus 30616 R-RNO-5218851 https://reactome.org/PathwayBrowser/#/R-RNO-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Rattus norvegicus 30616 R-RNO-5218854 https://reactome.org/PathwayBrowser/#/R-RNO-5218854 p-Y420-FYN is phosphorylated on S21 IEA Rattus norvegicus 30616 R-RNO-5218906 https://reactome.org/PathwayBrowser/#/R-RNO-5218906 RIPK3 phosphorylates MLKL IEA Rattus norvegicus 30616 R-RNO-5218916 https://reactome.org/PathwayBrowser/#/R-RNO-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Rattus norvegicus 30616 R-RNO-5223317 https://reactome.org/PathwayBrowser/#/R-RNO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Rattus norvegicus 30616 R-RNO-5229194 https://reactome.org/PathwayBrowser/#/R-RNO-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Rattus norvegicus 30616 R-RNO-5229343 https://reactome.org/PathwayBrowser/#/R-RNO-5229343 AXIN is phosphorylated in the destruction complex IEA Rattus norvegicus 30616 R-RNO-5244669 https://reactome.org/PathwayBrowser/#/R-RNO-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Rattus norvegicus 30616 R-RNO-5251942 https://reactome.org/PathwayBrowser/#/R-RNO-5251942 Hikeshi binds HSP70s:ATP IEA Rattus norvegicus 30616 R-RNO-5251955 https://reactome.org/PathwayBrowser/#/R-RNO-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Rattus norvegicus 30616 R-RNO-5251959 https://reactome.org/PathwayBrowser/#/R-RNO-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Rattus norvegicus 30616 R-RNO-5251989 https://reactome.org/PathwayBrowser/#/R-RNO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Rattus norvegicus 30616 R-RNO-5252041 https://reactome.org/PathwayBrowser/#/R-RNO-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Rattus norvegicus 30616 R-RNO-5252079 https://reactome.org/PathwayBrowser/#/R-RNO-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Rattus norvegicus 30616 R-RNO-5339524 https://reactome.org/PathwayBrowser/#/R-RNO-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Rattus norvegicus 30616 R-RNO-5357429 https://reactome.org/PathwayBrowser/#/R-RNO-5357429 AXL autophosphorylates on Y779 and Y821 IEA Rattus norvegicus 30616 R-RNO-5357472 https://reactome.org/PathwayBrowser/#/R-RNO-5357472 PAK1-3 autophosphorylates IEA Rattus norvegicus 30616 R-RNO-5357477 https://reactome.org/PathwayBrowser/#/R-RNO-5357477 PAK1-3 phosphorylates VE-cadherin IEA Rattus norvegicus 30616 R-RNO-5357831 https://reactome.org/PathwayBrowser/#/R-RNO-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Rattus norvegicus 30616 R-RNO-5358475 https://reactome.org/PathwayBrowser/#/R-RNO-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Rattus norvegicus 30616 R-RNO-5358510 https://reactome.org/PathwayBrowser/#/R-RNO-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Rattus norvegicus 30616 R-RNO-5358518 https://reactome.org/PathwayBrowser/#/R-RNO-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Rattus norvegicus 30616 R-RNO-5358592 https://reactome.org/PathwayBrowser/#/R-RNO-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Rattus norvegicus 30616 R-RNO-5358597 https://reactome.org/PathwayBrowser/#/R-RNO-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Rattus norvegicus 30616 R-RNO-5358599 https://reactome.org/PathwayBrowser/#/R-RNO-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Rattus norvegicus 30616 R-RNO-5358912 https://reactome.org/PathwayBrowser/#/R-RNO-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Rattus norvegicus 30616 R-RNO-5362459 https://reactome.org/PathwayBrowser/#/R-RNO-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Rattus norvegicus 30616 R-RNO-548843 https://reactome.org/PathwayBrowser/#/R-RNO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Rattus norvegicus 30616 R-RNO-548972 https://reactome.org/PathwayBrowser/#/R-RNO-548972 Phosphorylation of ITIM in SIRP alpha TAS Rattus norvegicus 30616 R-RNO-5578777 https://reactome.org/PathwayBrowser/#/R-RNO-5578777 DMPK phosphorylates PLN IEA Rattus norvegicus 30616 R-RNO-5603114 https://reactome.org/PathwayBrowser/#/R-RNO-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Rattus norvegicus 30616 R-RNO-5607722 https://reactome.org/PathwayBrowser/#/R-RNO-5607722 Active NIK phosphorylates IKKA dimer IEA Rattus norvegicus 30616 R-RNO-5607726 https://reactome.org/PathwayBrowser/#/R-RNO-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Rattus norvegicus 30616 R-RNO-5607732 https://reactome.org/PathwayBrowser/#/R-RNO-5607732 K63polyUb-TAK1 autophosphorylates IEA Rattus norvegicus 30616 R-RNO-5607740 https://reactome.org/PathwayBrowser/#/R-RNO-5607740 PKC-delta phosphorylates CARD9 IEA Rattus norvegicus 30616 R-RNO-5607742 https://reactome.org/PathwayBrowser/#/R-RNO-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Rattus norvegicus 30616 R-RNO-5607750 https://reactome.org/PathwayBrowser/#/R-RNO-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Rattus norvegicus 30616 R-RNO-5610720 https://reactome.org/PathwayBrowser/#/R-RNO-5610720 PKA phosphorylates GLI3 IEA Rattus norvegicus 30616 R-RNO-5610722 https://reactome.org/PathwayBrowser/#/R-RNO-5610722 CK1 phosphorylates p-GLI3 IEA Rattus norvegicus 30616 R-RNO-5610727 https://reactome.org/PathwayBrowser/#/R-RNO-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Rattus norvegicus 30616 R-RNO-5610732 https://reactome.org/PathwayBrowser/#/R-RNO-5610732 GSK3 phosphorylates p-GLI3 IEA Rattus norvegicus 30616 R-RNO-5617179 https://reactome.org/PathwayBrowser/#/R-RNO-5617179 PRKACA phosphorylates TNNI3 IEA Rattus norvegicus 30616 R-RNO-5617182 https://reactome.org/PathwayBrowser/#/R-RNO-5617182 PRKACA phosphorylates PLN IEA Rattus norvegicus 30616 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 30616 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 30616 R-RNO-5618085 https://reactome.org/PathwayBrowser/#/R-RNO-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Rattus norvegicus 30616 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 30616 R-RNO-5618098 https://reactome.org/PathwayBrowser/#/R-RNO-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Rattus norvegicus 30616 R-RNO-5618099 https://reactome.org/PathwayBrowser/#/R-RNO-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Rattus norvegicus 30616 R-RNO-5618105 https://reactome.org/PathwayBrowser/#/R-RNO-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Rattus norvegicus 30616 R-RNO-5618107 https://reactome.org/PathwayBrowser/#/R-RNO-5618107 ATP binding to HSP90 triggers conformation change IEA Rattus norvegicus 30616 R-RNO-5618110 https://reactome.org/PathwayBrowser/#/R-RNO-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Rattus norvegicus 30616 R-RNO-5621355 https://reactome.org/PathwayBrowser/#/R-RNO-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Rattus norvegicus 30616 R-RNO-5621363 https://reactome.org/PathwayBrowser/#/R-RNO-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Rattus norvegicus 30616 R-RNO-5621370 https://reactome.org/PathwayBrowser/#/R-RNO-5621370 SYK autophosphorylates IEA Rattus norvegicus 30616 R-RNO-5623667 https://reactome.org/PathwayBrowser/#/R-RNO-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Rattus norvegicus 30616 R-RNO-5624486 https://reactome.org/PathwayBrowser/#/R-RNO-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Rattus norvegicus 30616 R-RNO-5624492 https://reactome.org/PathwayBrowser/#/R-RNO-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Rattus norvegicus 30616 R-RNO-5625784 https://reactome.org/PathwayBrowser/#/R-RNO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Rattus norvegicus 30616 R-RNO-5626507 https://reactome.org/PathwayBrowser/#/R-RNO-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Rattus norvegicus 30616 R-RNO-5627775 https://reactome.org/PathwayBrowser/#/R-RNO-5627775 Autophosphorylation of PAK1,2,3 IEA Rattus norvegicus 30616 R-RNO-5635842 https://reactome.org/PathwayBrowser/#/R-RNO-5635842 ULK3 phosphorylates GLI IEA Rattus norvegicus 30616 R-RNO-5654147 https://reactome.org/PathwayBrowser/#/R-RNO-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Rattus norvegicus 30616 R-RNO-5654149 https://reactome.org/PathwayBrowser/#/R-RNO-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Rattus norvegicus 30616 R-RNO-5654151 https://reactome.org/PathwayBrowser/#/R-RNO-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Rattus norvegicus 30616 R-RNO-5654222 https://reactome.org/PathwayBrowser/#/R-RNO-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Rattus norvegicus 30616 R-RNO-5654397 https://reactome.org/PathwayBrowser/#/R-RNO-5654397 Activated FGFR2 phosphorylates FRS2 IEA Rattus norvegicus 30616 R-RNO-5654407 https://reactome.org/PathwayBrowser/#/R-RNO-5654407 Activated FGFR2 phosphorylates SHC1 IEA Rattus norvegicus 30616 R-RNO-5654408 https://reactome.org/PathwayBrowser/#/R-RNO-5654408 Activated FGFR3 phosphorylates FRS2 IEA Rattus norvegicus 30616 R-RNO-5654418 https://reactome.org/PathwayBrowser/#/R-RNO-5654418 Activated FGFR4 phosphorylates FRS2 IEA Rattus norvegicus 30616 R-RNO-5654428 https://reactome.org/PathwayBrowser/#/R-RNO-5654428 Activated FGFR4 phosphorylates SHC1 IEA Rattus norvegicus 30616 R-RNO-5654560 https://reactome.org/PathwayBrowser/#/R-RNO-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Rattus norvegicus 30616 R-RNO-5654562 https://reactome.org/PathwayBrowser/#/R-RNO-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Rattus norvegicus 30616 R-RNO-5654565 https://reactome.org/PathwayBrowser/#/R-RNO-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Rattus norvegicus 30616 R-RNO-5654566 https://reactome.org/PathwayBrowser/#/R-RNO-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Rattus norvegicus 30616 R-RNO-5654575 https://reactome.org/PathwayBrowser/#/R-RNO-5654575 Activated FGFR1 phosphorylates FRS2 IEA Rattus norvegicus 30616 R-RNO-5654578 https://reactome.org/PathwayBrowser/#/R-RNO-5654578 Activated FGFR1 phosphorylates FRS3 IEA Rattus norvegicus 30616 R-RNO-5654582 https://reactome.org/PathwayBrowser/#/R-RNO-5654582 Activated FGFR1 phosphorylates SHC1 IEA Rattus norvegicus 30616 R-RNO-5654587 https://reactome.org/PathwayBrowser/#/R-RNO-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Rattus norvegicus 30616 R-RNO-5654605 https://reactome.org/PathwayBrowser/#/R-RNO-5654605 Activated FGFR2 phosphorylates FRS3 IEA Rattus norvegicus 30616 R-RNO-5654607 https://reactome.org/PathwayBrowser/#/R-RNO-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Rattus norvegicus 30616 R-RNO-5654628 https://reactome.org/PathwayBrowser/#/R-RNO-5654628 Activated FGFR3 phosphorylates FRS3 IEA Rattus norvegicus 30616 R-RNO-5654631 https://reactome.org/PathwayBrowser/#/R-RNO-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Rattus norvegicus 30616 R-RNO-5654634 https://reactome.org/PathwayBrowser/#/R-RNO-5654634 Activated FGFR3 phosphorylates SHC1 IEA Rattus norvegicus 30616 R-RNO-5654653 https://reactome.org/PathwayBrowser/#/R-RNO-5654653 Activated FGFR4 phosphorylates FRS3 IEA Rattus norvegicus 30616 R-RNO-5654655 https://reactome.org/PathwayBrowser/#/R-RNO-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Rattus norvegicus 30616 R-RNO-5654690 https://reactome.org/PathwayBrowser/#/R-RNO-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-5654692 https://reactome.org/PathwayBrowser/#/R-RNO-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-5654697 https://reactome.org/PathwayBrowser/#/R-RNO-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-5654701 https://reactome.org/PathwayBrowser/#/R-RNO-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-5654705 https://reactome.org/PathwayBrowser/#/R-RNO-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-5654709 https://reactome.org/PathwayBrowser/#/R-RNO-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-5654714 https://reactome.org/PathwayBrowser/#/R-RNO-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-5654717 https://reactome.org/PathwayBrowser/#/R-RNO-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-5654989 https://reactome.org/PathwayBrowser/#/R-RNO-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Rattus norvegicus 30616 R-RNO-5662466 https://reactome.org/PathwayBrowser/#/R-RNO-5662466 XYLB phosphorylates D-xylulose IEA Rattus norvegicus 30616 R-RNO-5665751 https://reactome.org/PathwayBrowser/#/R-RNO-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin IEA Rattus norvegicus 30616 R-RNO-5665802 https://reactome.org/PathwayBrowser/#/R-RNO-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Rattus norvegicus 30616 R-RNO-5665809 https://reactome.org/PathwayBrowser/#/R-RNO-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Rattus norvegicus 30616 R-RNO-5665868 https://reactome.org/PathwayBrowser/#/R-RNO-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Rattus norvegicus 30616 R-RNO-5665982 https://reactome.org/PathwayBrowser/#/R-RNO-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 IEA Rattus norvegicus 30616 R-RNO-5666001 https://reactome.org/PathwayBrowser/#/R-RNO-5666001 Profilin:G-actin binds MKL1 IEA Rattus norvegicus 30616 R-RNO-5666160 https://reactome.org/PathwayBrowser/#/R-RNO-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Rattus norvegicus 30616 R-RNO-5668545 https://reactome.org/PathwayBrowser/#/R-RNO-5668545 NIK autophosphorylates on T559 IEA Rattus norvegicus 30616 R-RNO-5668932 https://reactome.org/PathwayBrowser/#/R-RNO-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Rattus norvegicus 30616 R-RNO-5668947 https://reactome.org/PathwayBrowser/#/R-RNO-5668947 PAK1 phosphorylates myosin phosphatase IEA Rattus norvegicus 30616 R-RNO-5668984 https://reactome.org/PathwayBrowser/#/R-RNO-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Rattus norvegicus 30616 R-RNO-5669250 https://reactome.org/PathwayBrowser/#/R-RNO-5669250 PAK1 phosphorylates FLNA IEA Rattus norvegicus 30616 R-RNO-5671749 https://reactome.org/PathwayBrowser/#/R-RNO-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Rattus norvegicus 30616 R-RNO-5671763 https://reactome.org/PathwayBrowser/#/R-RNO-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Rattus norvegicus 30616 R-RNO-5672008 https://reactome.org/PathwayBrowser/#/R-RNO-5672008 Thr-180 of ULK1 is phosphorylated IEA Rattus norvegicus 30616 R-RNO-5672010 https://reactome.org/PathwayBrowser/#/R-RNO-5672010 Active MTORC1 phosphorylates ULK1 IEA Rattus norvegicus 30616 R-RNO-5672012 https://reactome.org/PathwayBrowser/#/R-RNO-5672012 Beclin-1 complex phosphorylates PtdIns IEA Rattus norvegicus 30616 R-RNO-5672027 https://reactome.org/PathwayBrowser/#/R-RNO-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Rattus norvegicus 30616 R-RNO-5672828 https://reactome.org/PathwayBrowser/#/R-RNO-5672828 mTORC1 phosphorylates AKT1S1 IEA Rattus norvegicus 30616 R-RNO-5672948 https://reactome.org/PathwayBrowser/#/R-RNO-5672948 MARK3 phosphorylates KSR1 IEA Rattus norvegicus 30616 R-RNO-5672969 https://reactome.org/PathwayBrowser/#/R-RNO-5672969 Phosphorylation of RAF IEA Rattus norvegicus 30616 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 30616 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 30616 R-RNO-5673768 https://reactome.org/PathwayBrowser/#/R-RNO-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Rattus norvegicus 30616 R-RNO-5674130 https://reactome.org/PathwayBrowser/#/R-RNO-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Rattus norvegicus 30616 R-RNO-5674373 https://reactome.org/PathwayBrowser/#/R-RNO-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Rattus norvegicus 30616 R-RNO-5674496 https://reactome.org/PathwayBrowser/#/R-RNO-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Rattus norvegicus 30616 R-RNO-5675194 https://reactome.org/PathwayBrowser/#/R-RNO-5675194 Activated MAPK phosphorylates RAF1 IEA Rattus norvegicus 30616 R-RNO-5675198 https://reactome.org/PathwayBrowser/#/R-RNO-5675198 Activated MAPKs phosphorylate BRAF IEA Rattus norvegicus 30616 R-RNO-5675868 https://reactome.org/PathwayBrowser/#/R-RNO-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Rattus norvegicus 30616 R-RNO-5678706 https://reactome.org/PathwayBrowser/#/R-RNO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Rattus norvegicus 30616 R-RNO-5678863 https://reactome.org/PathwayBrowser/#/R-RNO-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-5679041 https://reactome.org/PathwayBrowser/#/R-RNO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-5679205 https://reactome.org/PathwayBrowser/#/R-RNO-5679205 ULK1 phosphorylates Beclin-1 IEA Rattus norvegicus 30616 R-RNO-5682026 https://reactome.org/PathwayBrowser/#/R-RNO-5682026 MRN bound to shortened telomeres activates ATM IEA Rattus norvegicus 30616 R-RNO-5682101 https://reactome.org/PathwayBrowser/#/R-RNO-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Rattus norvegicus 30616 R-RNO-5682285 https://reactome.org/PathwayBrowser/#/R-RNO-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-5682598 https://reactome.org/PathwayBrowser/#/R-RNO-5682598 ATM phosphorylates HERC2 IEA Rattus norvegicus 30616 R-RNO-5682983 https://reactome.org/PathwayBrowser/#/R-RNO-5682983 ATM phosphorylates WHSC1 IEA Rattus norvegicus 30616 R-RNO-5683425 https://reactome.org/PathwayBrowser/#/R-RNO-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Rattus norvegicus 30616 R-RNO-5683714 https://reactome.org/PathwayBrowser/#/R-RNO-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Rattus norvegicus 30616 R-RNO-5683792 https://reactome.org/PathwayBrowser/#/R-RNO-5683792 p-T68-CHEK2 autophosphorylates IEA Rattus norvegicus 30616 R-RNO-5683801 https://reactome.org/PathwayBrowser/#/R-RNO-5683801 CHEK2 phosphorylates BRCA1 IEA Rattus norvegicus 30616 R-RNO-5683930 https://reactome.org/PathwayBrowser/#/R-RNO-5683930 WICH phosphorylates H2AFX on Y142 IEA Rattus norvegicus 30616 R-RNO-5683964 https://reactome.org/PathwayBrowser/#/R-RNO-5683964 ATM phosphorylates EYA1-4 IEA Rattus norvegicus 30616 R-RNO-5684096 https://reactome.org/PathwayBrowser/#/R-RNO-5684096 CDK2 phosphorylates RBBP8 IEA Rattus norvegicus 30616 R-RNO-5684140 https://reactome.org/PathwayBrowser/#/R-RNO-5684140 ATM phosphorylates RBBP8 IEA Rattus norvegicus 30616 R-RNO-5684806 https://reactome.org/PathwayBrowser/#/R-RNO-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN IEA Rattus norvegicus 30616 R-RNO-5684862 https://reactome.org/PathwayBrowser/#/R-RNO-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Rattus norvegicus 30616 R-RNO-5684887 https://reactome.org/PathwayBrowser/#/R-RNO-5684887 Activation of CHEK1 at resected DNA DSBs IEA Rattus norvegicus 30616 R-RNO-5685156 https://reactome.org/PathwayBrowser/#/R-RNO-5685156 ATR phosphorylates RPA2 IEA Rattus norvegicus 30616 R-RNO-5685230 https://reactome.org/PathwayBrowser/#/R-RNO-5685230 CHEK1 phosphorylates RAD51 IEA Rattus norvegicus 30616 R-RNO-5686578 https://reactome.org/PathwayBrowser/#/R-RNO-5686578 Activated ATM phosphorylates ABL1 IEA Rattus norvegicus 30616 R-RNO-5686587 https://reactome.org/PathwayBrowser/#/R-RNO-5686587 ABL1 phosphorylates RAD52 IEA Rattus norvegicus 30616 R-RNO-5686704 https://reactome.org/PathwayBrowser/#/R-RNO-5686704 Activated ATM phosphorylates DCLRE1C IEA Rattus norvegicus 30616 R-RNO-5687086 https://reactome.org/PathwayBrowser/#/R-RNO-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Rattus norvegicus 30616 R-RNO-5687088 https://reactome.org/PathwayBrowser/#/R-RNO-5687088 PKA phosphorylates MAPKAPK5 IEA Rattus norvegicus 30616 R-RNO-5687090 https://reactome.org/PathwayBrowser/#/R-RNO-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Rattus norvegicus 30616 R-RNO-5687094 https://reactome.org/PathwayBrowser/#/R-RNO-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Rattus norvegicus 30616 R-RNO-5687101 https://reactome.org/PathwayBrowser/#/R-RNO-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Rattus norvegicus 30616 R-RNO-5687121 https://reactome.org/PathwayBrowser/#/R-RNO-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Rattus norvegicus 30616 R-RNO-5687183 https://reactome.org/PathwayBrowser/#/R-RNO-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Rattus norvegicus 30616 R-RNO-5690250 https://reactome.org/PathwayBrowser/#/R-RNO-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Rattus norvegicus 30616 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus 30616 R-RNO-5690996 https://reactome.org/PathwayBrowser/#/R-RNO-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Rattus norvegicus 30616 R-RNO-5692462 https://reactome.org/PathwayBrowser/#/R-RNO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Rattus norvegicus 30616 R-RNO-5692480 https://reactome.org/PathwayBrowser/#/R-RNO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Rattus norvegicus 30616 R-RNO-5692755 https://reactome.org/PathwayBrowser/#/R-RNO-5692755 CDK1 phosphorylates MAPK6 IEA Rattus norvegicus 30616 R-RNO-5692768 https://reactome.org/PathwayBrowser/#/R-RNO-5692768 MAPKAPK5 phosphorylates KALRN IEA Rattus norvegicus 30616 R-RNO-5692775 https://reactome.org/PathwayBrowser/#/R-RNO-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Rattus norvegicus 30616 R-RNO-5692779 https://reactome.org/PathwayBrowser/#/R-RNO-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Rattus norvegicus 30616 R-RNO-5693148 https://reactome.org/PathwayBrowser/#/R-RNO-5693148 BCKDK phosphorylates BCKDH IEA Rattus norvegicus 30616 R-RNO-5693536 https://reactome.org/PathwayBrowser/#/R-RNO-5693536 ATM phosphorylates MDC1 IEA Rattus norvegicus 30616 R-RNO-5693540 https://reactome.org/PathwayBrowser/#/R-RNO-5693540 MRN activates ATM IEA Rattus norvegicus 30616 R-RNO-5693549 https://reactome.org/PathwayBrowser/#/R-RNO-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Rattus norvegicus 30616 R-RNO-5693551 https://reactome.org/PathwayBrowser/#/R-RNO-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Rattus norvegicus 30616 R-RNO-5693575 https://reactome.org/PathwayBrowser/#/R-RNO-5693575 DNA-PKcs autophosphorylates IEA Rattus norvegicus 30616 R-RNO-5693598 https://reactome.org/PathwayBrowser/#/R-RNO-5693598 ATM phosphorylates NBN IEA Rattus norvegicus 30616 R-RNO-5693609 https://reactome.org/PathwayBrowser/#/R-RNO-5693609 ATM phosphorylates TP53 at S15 IEA Rattus norvegicus 30616 R-RNO-5694425 https://reactome.org/PathwayBrowser/#/R-RNO-5694425 NSF ATPase activity dissociates cis-SNARE IEA Rattus norvegicus 30616 R-RNO-5694441 https://reactome.org/PathwayBrowser/#/R-RNO-5694441 CSNK1D phosphorylates SEC23 IEA Rattus norvegicus 30616 R-RNO-5694494 https://reactome.org/PathwayBrowser/#/R-RNO-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Rattus norvegicus 30616 R-RNO-5695957 https://reactome.org/PathwayBrowser/#/R-RNO-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Rattus norvegicus 30616 R-RNO-5696004 https://reactome.org/PathwayBrowser/#/R-RNO-5696004 ACSF2 ligates CoA-SH to MCFA IEA Rattus norvegicus 30616 R-RNO-5696007 https://reactome.org/PathwayBrowser/#/R-RNO-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Rattus norvegicus 30616 R-RNO-5696074 https://reactome.org/PathwayBrowser/#/R-RNO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Rattus norvegicus 30616 R-RNO-5696839 https://reactome.org/PathwayBrowser/#/R-RNO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Rattus norvegicus 30616 R-RNO-622372 https://reactome.org/PathwayBrowser/#/R-RNO-622372 Phosphorylation of PLCgamma by Netrin-1 TAS Rattus norvegicus 30616 R-RNO-6782131 https://reactome.org/PathwayBrowser/#/R-RNO-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus 30616 R-RNO-6784006 https://reactome.org/PathwayBrowser/#/R-RNO-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Rattus norvegicus 30616 R-RNO-6784319 https://reactome.org/PathwayBrowser/#/R-RNO-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Rattus norvegicus 30616 R-RNO-6784324 https://reactome.org/PathwayBrowser/#/R-RNO-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Rattus norvegicus 30616 R-RNO-6786050 https://reactome.org/PathwayBrowser/#/R-RNO-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Rattus norvegicus 30616 R-RNO-6786095 https://reactome.org/PathwayBrowser/#/R-RNO-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Rattus norvegicus 30616 R-RNO-6786096 https://reactome.org/PathwayBrowser/#/R-RNO-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Rattus norvegicus 30616 R-RNO-6786245 https://reactome.org/PathwayBrowser/#/R-RNO-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Rattus norvegicus 30616 R-RNO-6787540 https://reactome.org/PathwayBrowser/#/R-RNO-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Rattus norvegicus 30616 R-RNO-6788392 https://reactome.org/PathwayBrowser/#/R-RNO-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Rattus norvegicus 30616 R-RNO-6788582 https://reactome.org/PathwayBrowser/#/R-RNO-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Rattus norvegicus 30616 R-RNO-6788798 https://reactome.org/PathwayBrowser/#/R-RNO-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 30616 R-RNO-6788810 https://reactome.org/PathwayBrowser/#/R-RNO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 30616 R-RNO-6788855 https://reactome.org/PathwayBrowser/#/R-RNO-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Rattus norvegicus 30616 R-RNO-6788867 https://reactome.org/PathwayBrowser/#/R-RNO-6788867 FN3K phosphorylates ketosamines IEA Rattus norvegicus 30616 R-RNO-6793661 https://reactome.org/PathwayBrowser/#/R-RNO-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Rattus norvegicus 30616 R-RNO-6795290 https://reactome.org/PathwayBrowser/#/R-RNO-6795290 TORC2 complex phosphorylates SGK1 IEA Rattus norvegicus 30616 R-RNO-6795460 https://reactome.org/PathwayBrowser/#/R-RNO-6795460 SGK1 phosphorylates MDM2 IEA Rattus norvegicus 30616 R-RNO-6795473 https://reactome.org/PathwayBrowser/#/R-RNO-6795473 PDPK1 phosphorylates SGK1 IEA Rattus norvegicus 30616 R-RNO-6797606 https://reactome.org/PathwayBrowser/#/R-RNO-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Rattus norvegicus 30616 R-RNO-6798174 https://reactome.org/PathwayBrowser/#/R-RNO-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Rattus norvegicus 30616 R-RNO-6798372 https://reactome.org/PathwayBrowser/#/R-RNO-6798372 ATM phosphorylates DYRK2 IEA Rattus norvegicus 30616 R-RNO-6798374 https://reactome.org/PathwayBrowser/#/R-RNO-6798374 DYRK2 phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6799097 https://reactome.org/PathwayBrowser/#/R-RNO-6799097 ATM phosphorylates ZNF420 IEA Rattus norvegicus 30616 R-RNO-6799246 https://reactome.org/PathwayBrowser/#/R-RNO-6799246 CHEK1 phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6799332 https://reactome.org/PathwayBrowser/#/R-RNO-6799332 ATR phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6799495 https://reactome.org/PathwayBrowser/#/R-RNO-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Rattus norvegicus 30616 R-RNO-6800490 https://reactome.org/PathwayBrowser/#/R-RNO-6800490 ATM phosphorylates PIDD1 IEA Rattus norvegicus 30616 R-RNO-6801342 https://reactome.org/PathwayBrowser/#/R-RNO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Rattus norvegicus 30616 R-RNO-6801456 https://reactome.org/PathwayBrowser/#/R-RNO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Rattus norvegicus 30616 R-RNO-6801666 https://reactome.org/PathwayBrowser/#/R-RNO-6801666 PLK2 phosphorylates CENPJ IEA Rattus norvegicus 30616 R-RNO-6801675 https://reactome.org/PathwayBrowser/#/R-RNO-6801675 PLK2 phosphorylates NPM1 IEA Rattus norvegicus 30616 R-RNO-6802973 https://reactome.org/PathwayBrowser/#/R-RNO-6802973 PLK3 phosphorylates CDC25C IEA Rattus norvegicus 30616 R-RNO-6803545 https://reactome.org/PathwayBrowser/#/R-RNO-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Rattus norvegicus 30616 R-RNO-6803771 https://reactome.org/PathwayBrowser/#/R-RNO-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Rattus norvegicus 30616 R-RNO-6804266 https://reactome.org/PathwayBrowser/#/R-RNO-6804266 CHEK2 phosphorylates TTC5 IEA Rattus norvegicus 30616 R-RNO-6804276 https://reactome.org/PathwayBrowser/#/R-RNO-6804276 ATM phosphorylates TTC5 IEA Rattus norvegicus 30616 R-RNO-6804596 https://reactome.org/PathwayBrowser/#/R-RNO-6804596 APAF1:CYCS binds APIP IEA Rattus norvegicus 30616 R-RNO-6804955 https://reactome.org/PathwayBrowser/#/R-RNO-6804955 ATM phosphorylates MDM2 IEA Rattus norvegicus 30616 R-RNO-6805059 https://reactome.org/PathwayBrowser/#/R-RNO-6805059 CK2:FACT phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6805103 https://reactome.org/PathwayBrowser/#/R-RNO-6805103 AURKA phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6805109 https://reactome.org/PathwayBrowser/#/R-RNO-6805109 CDK2 phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6805126 https://reactome.org/PathwayBrowser/#/R-RNO-6805126 AURKB phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6805276 https://reactome.org/PathwayBrowser/#/R-RNO-6805276 CDK5 phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6805285 https://reactome.org/PathwayBrowser/#/R-RNO-6805285 PLK3 phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6805399 https://reactome.org/PathwayBrowser/#/R-RNO-6805399 TAF1 phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6805470 https://reactome.org/PathwayBrowser/#/R-RNO-6805470 AMPK phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6805479 https://reactome.org/PathwayBrowser/#/R-RNO-6805479 TP53RK phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-6805640 https://reactome.org/PathwayBrowser/#/R-RNO-6805640 AKT phosphorylates KAT6A IEA Rattus norvegicus 30616 R-RNO-6805785 https://reactome.org/PathwayBrowser/#/R-RNO-6805785 AKT phosphorylates PHF20 IEA Rattus norvegicus 30616 R-RNO-6806877 https://reactome.org/PathwayBrowser/#/R-RNO-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Rattus norvegicus 30616 R-RNO-6806967 https://reactome.org/PathwayBrowser/#/R-RNO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Rattus norvegicus 30616 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 30616 R-RNO-6807868 https://reactome.org/PathwayBrowser/#/R-RNO-6807868 GBF1 stimulates ARF nucleotide exchange IEA Rattus norvegicus 30616 R-RNO-6809015 https://reactome.org/PathwayBrowser/#/R-RNO-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Rattus norvegicus 30616 R-RNO-6810233 https://reactome.org/PathwayBrowser/#/R-RNO-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Rattus norvegicus 30616 R-RNO-6811422 https://reactome.org/PathwayBrowser/#/R-RNO-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Rattus norvegicus 30616 R-RNO-6811454 https://reactome.org/PathwayBrowser/#/R-RNO-6811454 MAPKs phosphorylate PP2A IEA Rattus norvegicus 30616 R-RNO-6811522 https://reactome.org/PathwayBrowser/#/R-RNO-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Rattus norvegicus 30616 R-RNO-6814120 https://reactome.org/PathwayBrowser/#/R-RNO-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Rattus norvegicus 30616 R-RNO-6814124 https://reactome.org/PathwayBrowser/#/R-RNO-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Rattus norvegicus 30616 R-RNO-6814409 https://reactome.org/PathwayBrowser/#/R-RNO-6814409 CK2 phosphorylates PDCL IEA Rattus norvegicus 30616 R-RNO-6814549 https://reactome.org/PathwayBrowser/#/R-RNO-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Rattus norvegicus 30616 R-RNO-6814559 https://reactome.org/PathwayBrowser/#/R-RNO-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Rattus norvegicus 30616 R-RNO-6814675 https://reactome.org/PathwayBrowser/#/R-RNO-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Rattus norvegicus 30616 R-RNO-6814683 https://reactome.org/PathwayBrowser/#/R-RNO-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Rattus norvegicus 30616 R-RNO-68610 https://reactome.org/PathwayBrowser/#/R-RNO-68610 Formation of ORC(2-5) complex IEA Rattus norvegicus 30616 R-RNO-68944 https://reactome.org/PathwayBrowser/#/R-RNO-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Rattus norvegicus 30616 R-RNO-68954 https://reactome.org/PathwayBrowser/#/R-RNO-68954 Mcm2-7 is phosphorylated by DDK IEA Rattus norvegicus 30616 R-RNO-69005 https://reactome.org/PathwayBrowser/#/R-RNO-69005 Cdc6 protein is phosphorylated by CDK IEA Rattus norvegicus 30616 R-RNO-69015 https://reactome.org/PathwayBrowser/#/R-RNO-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Rattus norvegicus 30616 R-RNO-69063 https://reactome.org/PathwayBrowser/#/R-RNO-69063 Loading of PCNA - Sliding Clamp Formation IEA Rattus norvegicus 30616 R-RNO-69195 https://reactome.org/PathwayBrowser/#/R-RNO-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Rattus norvegicus 30616 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 30616 R-RNO-69604 https://reactome.org/PathwayBrowser/#/R-RNO-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Rattus norvegicus 30616 R-RNO-69608 https://reactome.org/PathwayBrowser/#/R-RNO-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Rattus norvegicus 30616 R-RNO-69685 https://reactome.org/PathwayBrowser/#/R-RNO-69685 CHEK2 phosphorylates TP53 IEA Rattus norvegicus 30616 R-RNO-69891 https://reactome.org/PathwayBrowser/#/R-RNO-69891 Phosphorylation and activation of CHEK2 by ATM IEA Rattus norvegicus 30616 R-RNO-70333 https://reactome.org/PathwayBrowser/#/R-RNO-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Rattus norvegicus 30616 R-RNO-70349 https://reactome.org/PathwayBrowser/#/R-RNO-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 30616 R-RNO-70355 https://reactome.org/PathwayBrowser/#/R-RNO-70355 GALK1 phosphorylates Gal to Gal1P IEA Rattus norvegicus 30616 R-RNO-70420 https://reactome.org/PathwayBrowser/#/R-RNO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Rattus norvegicus 30616 R-RNO-70467 https://reactome.org/PathwayBrowser/#/R-RNO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Rattus norvegicus 30616 R-RNO-70486 https://reactome.org/PathwayBrowser/#/R-RNO-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Rattus norvegicus 30616 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 30616 R-RNO-70555 https://reactome.org/PathwayBrowser/#/R-RNO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Rattus norvegicus 30616 R-RNO-70599 https://reactome.org/PathwayBrowser/#/R-RNO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Rattus norvegicus 30616 R-RNO-70606 https://reactome.org/PathwayBrowser/#/R-RNO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Rattus norvegicus 30616 R-RNO-70773 https://reactome.org/PathwayBrowser/#/R-RNO-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Rattus norvegicus 30616 R-RNO-70967 https://reactome.org/PathwayBrowser/#/R-RNO-70967 IDH3 complex decarboxylates isocitrate IEA Rattus norvegicus 30616 R-RNO-70997 https://reactome.org/PathwayBrowser/#/R-RNO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Rattus norvegicus 30616 R-RNO-71031 https://reactome.org/PathwayBrowser/#/R-RNO-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Rattus norvegicus 30616 R-RNO-71401 https://reactome.org/PathwayBrowser/#/R-RNO-71401 OGDH dimer decarboxylates 2-OG IEA Rattus norvegicus 30616 R-RNO-71541 https://reactome.org/PathwayBrowser/#/R-RNO-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Rattus norvegicus 30616 R-RNO-71588 https://reactome.org/PathwayBrowser/#/R-RNO-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Rattus norvegicus 30616 R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 30616 R-RNO-71735 https://reactome.org/PathwayBrowser/#/R-RNO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Rattus norvegicus 30616 R-RNO-71802 https://reactome.org/PathwayBrowser/#/R-RNO-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Rattus norvegicus 30616 R-RNO-71850 https://reactome.org/PathwayBrowser/#/R-RNO-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Rattus norvegicus 30616 R-RNO-72180 https://reactome.org/PathwayBrowser/#/R-RNO-72180 Cleavage of mRNA at the 3'-end IEA Rattus norvegicus 30616 R-RNO-72185 https://reactome.org/PathwayBrowser/#/R-RNO-72185 mRNA polyadenylation IEA Rattus norvegicus 30616 R-RNO-72621 https://reactome.org/PathwayBrowser/#/R-RNO-72621 Ribosomal scanning IEA Rattus norvegicus 30616 R-RNO-727819 https://reactome.org/PathwayBrowser/#/R-RNO-727819 TAK1 phosphorylates MKK6 IEA Rattus norvegicus 30616 R-RNO-73548 https://reactome.org/PathwayBrowser/#/R-RNO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Rattus norvegicus 30616 R-RNO-73577 https://reactome.org/PathwayBrowser/#/R-RNO-73577 CAD hexamer transforms L-Gln to CAP IEA Rattus norvegicus 30616 R-RNO-73580 https://reactome.org/PathwayBrowser/#/R-RNO-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Rattus norvegicus 30616 R-RNO-73598 https://reactome.org/PathwayBrowser/#/R-RNO-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Rattus norvegicus 30616 R-RNO-73599 https://reactome.org/PathwayBrowser/#/R-RNO-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Rattus norvegicus 30616 R-RNO-73632 https://reactome.org/PathwayBrowser/#/R-RNO-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Rattus norvegicus 30616 R-RNO-73635 https://reactome.org/PathwayBrowser/#/R-RNO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Rattus norvegicus 30616 R-RNO-73647 https://reactome.org/PathwayBrowser/#/R-RNO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Rattus norvegicus 30616 R-RNO-73722 https://reactome.org/PathwayBrowser/#/R-RNO-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Rattus norvegicus 30616 R-RNO-73788 https://reactome.org/PathwayBrowser/#/R-RNO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Rattus norvegicus 30616 R-RNO-73792 https://reactome.org/PathwayBrowser/#/R-RNO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Rattus norvegicus 30616 R-RNO-73805 https://reactome.org/PathwayBrowser/#/R-RNO-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Rattus norvegicus 30616 R-RNO-73810 https://reactome.org/PathwayBrowser/#/R-RNO-73810 FGAM + ATP => AIR + ADP + Pi IEA Rattus norvegicus 30616 R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 30616 R-RNO-73814 https://reactome.org/PathwayBrowser/#/R-RNO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Rattus norvegicus 30616 R-RNO-74207 https://reactome.org/PathwayBrowser/#/R-RNO-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Rattus norvegicus 30616 R-RNO-74220 https://reactome.org/PathwayBrowser/#/R-RNO-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Rattus norvegicus 30616 R-RNO-74711 https://reactome.org/PathwayBrowser/#/R-RNO-74711 Phosphorylation of IRS IEA Rattus norvegicus 30616 R-RNO-74715 https://reactome.org/PathwayBrowser/#/R-RNO-74715 Autophosphorylation of insulin receptor IEA Rattus norvegicus 30616 R-RNO-74742 https://reactome.org/PathwayBrowser/#/R-RNO-74742 Phosphorylation of SHC1 IEA Rattus norvegicus 30616 R-RNO-75010 https://reactome.org/PathwayBrowser/#/R-RNO-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Rattus norvegicus 30616 R-RNO-75125 https://reactome.org/PathwayBrowser/#/R-RNO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Rattus norvegicus 30616 R-RNO-75126 https://reactome.org/PathwayBrowser/#/R-RNO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Rattus norvegicus 30616 R-RNO-75809 https://reactome.org/PathwayBrowser/#/R-RNO-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Rattus norvegicus 30616 R-RNO-75848 https://reactome.org/PathwayBrowser/#/R-RNO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Rattus norvegicus 30616 R-RNO-75851 https://reactome.org/PathwayBrowser/#/R-RNO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 30616 R-RNO-75887 https://reactome.org/PathwayBrowser/#/R-RNO-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Rattus norvegicus 30616 R-RNO-75949 https://reactome.org/PathwayBrowser/#/R-RNO-75949 RNA Polymerase II Promoter Opening: First Transition IEA Rattus norvegicus 30616 R-RNO-77071 https://reactome.org/PathwayBrowser/#/R-RNO-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Rattus norvegicus 30616 R-RNO-844438 https://reactome.org/PathwayBrowser/#/R-RNO-844438 NLRP1 oligomerizes IEA Rattus norvegicus 30616 R-RNO-873918 https://reactome.org/PathwayBrowser/#/R-RNO-873918 Transphosphorylation of JAK1 IEA Rattus norvegicus 30616 R-RNO-873919 https://reactome.org/PathwayBrowser/#/R-RNO-873919 Phosphorylation of JAK2 IEA Rattus norvegicus 30616 R-RNO-873922 https://reactome.org/PathwayBrowser/#/R-RNO-873922 Phosphorylation of STAT1 by JAK kinases IEA Rattus norvegicus 30616 R-RNO-873924 https://reactome.org/PathwayBrowser/#/R-RNO-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Rattus norvegicus 30616 R-RNO-877187 https://reactome.org/PathwayBrowser/#/R-RNO-877187 P2X7 mediates loss of intracellular K+ IEA Rattus norvegicus 30616 R-RNO-877198 https://reactome.org/PathwayBrowser/#/R-RNO-877198 P2X7 mediates membrane pores that include pannexin-1 IEA Rattus norvegicus 30616 R-RNO-877219 https://reactome.org/PathwayBrowser/#/R-RNO-877219 ATP binds to p2x7 TAS Rattus norvegicus 30616 R-RNO-877248 https://reactome.org/PathwayBrowser/#/R-RNO-877248 p2x7 forms oligomeric non-selective cation channels TAS Rattus norvegicus 30616 R-RNO-879222 https://reactome.org/PathwayBrowser/#/R-RNO-879222 MDP:NLRP1 binds ATP IEA Rattus norvegicus 30616 R-RNO-879907 https://reactome.org/PathwayBrowser/#/R-RNO-879907 Tyrosine kinases phosphorylate the receptor IEA Rattus norvegicus 30616 R-RNO-879909 https://reactome.org/PathwayBrowser/#/R-RNO-879909 Activation of STAT5a/b by JAK2 IEA Rattus norvegicus 30616 R-RNO-879910 https://reactome.org/PathwayBrowser/#/R-RNO-879910 JAK2 is phosphorylated, activated IEA Rattus norvegicus 30616 R-RNO-8847638 https://reactome.org/PathwayBrowser/#/R-RNO-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Rattus norvegicus 30616 R-RNO-8847977 https://reactome.org/PathwayBrowser/#/R-RNO-8847977 FRK phosphorylates PTEN IEA Rattus norvegicus 30616 R-RNO-8848005 https://reactome.org/PathwayBrowser/#/R-RNO-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Rattus norvegicus 30616 R-RNO-8848053 https://reactome.org/PathwayBrowser/#/R-RNO-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Rattus norvegicus 30616 R-RNO-8848077 https://reactome.org/PathwayBrowser/#/R-RNO-8848077 PTK6 phosphorylates STAP2 IEA Rattus norvegicus 30616 R-RNO-8848124 https://reactome.org/PathwayBrowser/#/R-RNO-8848124 PTK6 phosphorylates STAT3 IEA Rattus norvegicus 30616 R-RNO-8848436 https://reactome.org/PathwayBrowser/#/R-RNO-8848436 PTK6 phosphorylates CDKN1B IEA Rattus norvegicus 30616 R-RNO-8848606 https://reactome.org/PathwayBrowser/#/R-RNO-8848606 PTK6 phosphorylates PXN IEA Rattus norvegicus 30616 R-RNO-8848726 https://reactome.org/PathwayBrowser/#/R-RNO-8848726 PTK6 phosphorylates BCAR1 IEA Rattus norvegicus 30616 R-RNO-8848758 https://reactome.org/PathwayBrowser/#/R-RNO-8848758 PTK6 phosphorylates AKT1 IEA Rattus norvegicus 30616 R-RNO-8848776 https://reactome.org/PathwayBrowser/#/R-RNO-8848776 PTK6 phosphorylates DOK1 IEA Rattus norvegicus 30616 R-RNO-8848818 https://reactome.org/PathwayBrowser/#/R-RNO-8848818 PTK6 phosphorylates CBL IEA Rattus norvegicus 30616 R-RNO-8848873 https://reactome.org/PathwayBrowser/#/R-RNO-8848873 PTK6 phosphorylates ARAP1 IEA Rattus norvegicus 30616 R-RNO-8848975 https://reactome.org/PathwayBrowser/#/R-RNO-8848975 PTK6 phosphorylates KHDRBS1 IEA Rattus norvegicus 30616 R-RNO-8849032 https://reactome.org/PathwayBrowser/#/R-RNO-8849032 PTK6 phosphorylates KHDRBS2 IEA Rattus norvegicus 30616 R-RNO-8849042 https://reactome.org/PathwayBrowser/#/R-RNO-8849042 PTK6 phosphorylates KHDRBS3 IEA Rattus norvegicus 30616 R-RNO-8849068 https://reactome.org/PathwayBrowser/#/R-RNO-8849068 PTK6 phosphorylates ARHGAP35 IEA Rattus norvegicus 30616 R-RNO-8849102 https://reactome.org/PathwayBrowser/#/R-RNO-8849102 SRMS phosphorylates PTK6 IEA Rattus norvegicus 30616 R-RNO-8849353 https://reactome.org/PathwayBrowser/#/R-RNO-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Rattus norvegicus 30616 R-RNO-8849463 https://reactome.org/PathwayBrowser/#/R-RNO-8849463 PTK6 phosphorylates SFPQ IEA Rattus norvegicus 30616 R-RNO-8850945 https://reactome.org/PathwayBrowser/#/R-RNO-8850945 Casein kinase II phosphorylates PTEN IEA Rattus norvegicus 30616 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 30616 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 30616 R-RNO-8851797 https://reactome.org/PathwayBrowser/#/R-RNO-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Rattus norvegicus 30616 R-RNO-8851890 https://reactome.org/PathwayBrowser/#/R-RNO-8851890 MET phosphorylates SHC1-2 IEA Rattus norvegicus 30616 R-RNO-8851933 https://reactome.org/PathwayBrowser/#/R-RNO-8851933 MET phosphorylates GAB1 IEA Rattus norvegicus 30616 R-RNO-8852019 https://reactome.org/PathwayBrowser/#/R-RNO-8852019 MET bound PI3K generates PIP3 IEA Rattus norvegicus 30616 R-RNO-8852128 https://reactome.org/PathwayBrowser/#/R-RNO-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Rattus norvegicus 30616 R-RNO-8852131 https://reactome.org/PathwayBrowser/#/R-RNO-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Rattus norvegicus 30616 R-RNO-8852132 https://reactome.org/PathwayBrowser/#/R-RNO-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Rattus norvegicus 30616 R-RNO-8852134 https://reactome.org/PathwayBrowser/#/R-RNO-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Rattus norvegicus 30616 R-RNO-8852306 https://reactome.org/PathwayBrowser/#/R-RNO-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Rattus norvegicus 30616 R-RNO-8852317 https://reactome.org/PathwayBrowser/#/R-RNO-8852317 PLK1 phosphorylates GTSE1 IEA Rattus norvegicus 30616 R-RNO-8852552 https://reactome.org/PathwayBrowser/#/R-RNO-8852552 MST1R autophosphorylates IEA Rattus norvegicus 30616 R-RNO-8853419 https://reactome.org/PathwayBrowser/#/R-RNO-8853419 TPX2 promotes AURKA autophosphorylation IEA Rattus norvegicus 30616 R-RNO-8853444 https://reactome.org/PathwayBrowser/#/R-RNO-8853444 AURKA phosphorylates PHLDA1 IEA Rattus norvegicus 30616 R-RNO-8853774 https://reactome.org/PathwayBrowser/#/R-RNO-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Rattus norvegicus 30616 R-RNO-8853792 https://reactome.org/PathwayBrowser/#/R-RNO-8853792 RET tyrosine phosphorylation IEA Rattus norvegicus 30616 R-RNO-8854908 https://reactome.org/PathwayBrowser/#/R-RNO-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Rattus norvegicus 30616 R-RNO-8855237 https://reactome.org/PathwayBrowser/#/R-RNO-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Rattus norvegicus 30616 R-RNO-8856813 https://reactome.org/PathwayBrowser/#/R-RNO-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Rattus norvegicus 30616 R-RNO-8857555 https://reactome.org/PathwayBrowser/#/R-RNO-8857555 EGFR phosphorylates GPNMB IEA Rattus norvegicus 30616 R-RNO-8857577 https://reactome.org/PathwayBrowser/#/R-RNO-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Rattus norvegicus 30616 R-RNO-8857583 https://reactome.org/PathwayBrowser/#/R-RNO-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Rattus norvegicus 30616 R-RNO-8857925 https://reactome.org/PathwayBrowser/#/R-RNO-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Rattus norvegicus 30616 R-RNO-8865774 https://reactome.org/PathwayBrowser/#/R-RNO-8865774 TTLLs polyglutamylate tubulin IEA Rattus norvegicus 30616 R-RNO-8866268 https://reactome.org/PathwayBrowser/#/R-RNO-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Rattus norvegicus 30616 R-RNO-8866405 https://reactome.org/PathwayBrowser/#/R-RNO-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 30616 R-RNO-8866542 https://reactome.org/PathwayBrowser/#/R-RNO-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Rattus norvegicus 30616 R-RNO-8867041 https://reactome.org/PathwayBrowser/#/R-RNO-8867041 EGFR phosphorylates EPS15 IEA Rattus norvegicus 30616 R-RNO-8867370 https://reactome.org/PathwayBrowser/#/R-RNO-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Rattus norvegicus 30616 R-RNO-8868066 https://reactome.org/PathwayBrowser/#/R-RNO-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Rattus norvegicus 30616 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 30616 R-RNO-8868118 https://reactome.org/PathwayBrowser/#/R-RNO-8868118 MAPK12 phosphorylates PTPN3 IEA Rattus norvegicus 30616 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus 30616 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 30616 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus 30616 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 30616 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus 30616 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus 30616 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 30616 R-RNO-8869606 https://reactome.org/PathwayBrowser/#/R-RNO-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Rattus norvegicus 30616 R-RNO-8869633 https://reactome.org/PathwayBrowser/#/R-RNO-8869633 NMRK1 phosphorylates NR to yield NMN IEA Rattus norvegicus 30616 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 30616 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus 30616 R-RNO-8871373 https://reactome.org/PathwayBrowser/#/R-RNO-8871373 BMX phosphorylates RUFY1 IEA Rattus norvegicus 30616 R-RNO-8873929 https://reactome.org/PathwayBrowser/#/R-RNO-8873929 Casein kinase II phosphorylates STARD10 IEA Rattus norvegicus 30616 R-RNO-8874078 https://reactome.org/PathwayBrowser/#/R-RNO-8874078 PTK2 autophosphorylates IEA Rattus norvegicus 30616 R-RNO-8874080 https://reactome.org/PathwayBrowser/#/R-RNO-8874080 SRC phosphorylates PTK2 IEA Rattus norvegicus 30616 R-RNO-8874082 https://reactome.org/PathwayBrowser/#/R-RNO-8874082 MET phosphorylates PTK2 IEA Rattus norvegicus 30616 R-RNO-8875071 https://reactome.org/PathwayBrowser/#/R-RNO-8875071 ACSS3 ligates CoA to CH3COO- IEA Rattus norvegicus 30616 R-RNO-8875451 https://reactome.org/PathwayBrowser/#/R-RNO-8875451 MET phosphorylates CBL IEA Rattus norvegicus 30616 R-RNO-8875817 https://reactome.org/PathwayBrowser/#/R-RNO-8875817 MET phosphorylates STAT3 IEA Rattus norvegicus 30616 R-RNO-8876446 https://reactome.org/PathwayBrowser/#/R-RNO-8876446 p-ULK1 phosphorylates DENND3 IEA Rattus norvegicus 30616 R-RNO-8876889 https://reactome.org/PathwayBrowser/#/R-RNO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 30616 R-RNO-8877691 https://reactome.org/PathwayBrowser/#/R-RNO-8877691 MAP2K6 phosphorylates PIP4K2B IEA Rattus norvegicus 30616 R-RNO-8931653 https://reactome.org/PathwayBrowser/#/R-RNO-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Rattus norvegicus 30616 R-RNO-8932373 https://reactome.org/PathwayBrowser/#/R-RNO-8932373 PKC phosphorylates Nrf2 TAS Rattus norvegicus 30616 R-RNO-8933446 https://reactome.org/PathwayBrowser/#/R-RNO-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Rattus norvegicus 30616 R-RNO-8934446 https://reactome.org/PathwayBrowser/#/R-RNO-8934446 Activated PKC phosphorylates SHC1 IEA Rattus norvegicus 30616 R-RNO-8937807 https://reactome.org/PathwayBrowser/#/R-RNO-8937807 SRC phosphorylates RUNX3 IEA Rattus norvegicus 30616 R-RNO-8937915 https://reactome.org/PathwayBrowser/#/R-RNO-8937915 Src,Yes1 phosphorylate Yap1 TAS Rattus norvegicus 30616 R-RNO-8939204 https://reactome.org/PathwayBrowser/#/R-RNO-8939204 ESTG binds ESR1:chaperone complex IEA Rattus norvegicus 30616 R-RNO-8939959 https://reactome.org/PathwayBrowser/#/R-RNO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Rattus norvegicus 30616 R-RNO-8940100 https://reactome.org/PathwayBrowser/#/R-RNO-8940100 CDK1 phosphorylates VCPIP1 IEA Rattus norvegicus 30616 R-RNO-8942575 https://reactome.org/PathwayBrowser/#/R-RNO-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Rattus norvegicus 30616 R-RNO-8942607 https://reactome.org/PathwayBrowser/#/R-RNO-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Rattus norvegicus 30616 R-RNO-8942836 https://reactome.org/PathwayBrowser/#/R-RNO-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Rattus norvegicus 30616 R-RNO-8944454 https://reactome.org/PathwayBrowser/#/R-RNO-8944454 mTORC1 phosphorylates MAF1 IEA Rattus norvegicus 30616 R-RNO-8948039 https://reactome.org/PathwayBrowser/#/R-RNO-8948039 FUNDC1 is phosphorylated by CK2 IEA Rattus norvegicus 30616 R-RNO-8948143 https://reactome.org/PathwayBrowser/#/R-RNO-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Rattus norvegicus 30616 R-RNO-8948146 https://reactome.org/PathwayBrowser/#/R-RNO-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Rattus norvegicus 30616 R-RNO-8948757 https://reactome.org/PathwayBrowser/#/R-RNO-8948757 AKT phosphorylates MKRN1 IEA Rattus norvegicus 30616 R-RNO-8950269 https://reactome.org/PathwayBrowser/#/R-RNO-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Rattus norvegicus 30616 R-RNO-8950340 https://reactome.org/PathwayBrowser/#/R-RNO-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Rattus norvegicus 30616 R-RNO-8950405 https://reactome.org/PathwayBrowser/#/R-RNO-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Rattus norvegicus 30616 R-RNO-8950423 https://reactome.org/PathwayBrowser/#/R-RNO-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Rattus norvegicus 30616 R-RNO-8950453 https://reactome.org/PathwayBrowser/#/R-RNO-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Rattus norvegicus 30616 R-RNO-8950485 https://reactome.org/PathwayBrowser/#/R-RNO-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Rattus norvegicus 30616 R-RNO-8950537 https://reactome.org/PathwayBrowser/#/R-RNO-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Rattus norvegicus 30616 R-RNO-8950757 https://reactome.org/PathwayBrowser/#/R-RNO-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Rattus norvegicus 30616 R-RNO-8951648 https://reactome.org/PathwayBrowser/#/R-RNO-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Rattus norvegicus 30616 R-RNO-8951656 https://reactome.org/PathwayBrowser/#/R-RNO-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Rattus norvegicus 30616 R-RNO-8952289 https://reactome.org/PathwayBrowser/#/R-RNO-8952289 FAM20C phosphorylates FAM20C substrates IEA Rattus norvegicus 30616 R-RNO-8954327 https://reactome.org/PathwayBrowser/#/R-RNO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Rattus norvegicus 30616 R-RNO-8955030 https://reactome.org/PathwayBrowser/#/R-RNO-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 30616 R-RNO-8955844 https://reactome.org/PathwayBrowser/#/R-RNO-8955844 RBKS phosphorylates ribose to R5P IEA Rattus norvegicus 30616 R-RNO-8956659 https://reactome.org/PathwayBrowser/#/R-RNO-8956659 ABL1 phosphorylates YAP1 IEA Rattus norvegicus 30616 R-RNO-8959510 https://reactome.org/PathwayBrowser/#/R-RNO-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Rattus norvegicus 30616 R-RNO-8959719 https://reactome.org/PathwayBrowser/#/R-RNO-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Rattus norvegicus 30616 R-RNO-8964242 https://reactome.org/PathwayBrowser/#/R-RNO-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Rattus norvegicus 30616 R-RNO-8982163 https://reactome.org/PathwayBrowser/#/R-RNO-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Rattus norvegicus 30616 R-RNO-8983059 https://reactome.org/PathwayBrowser/#/R-RNO-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Rattus norvegicus 30616 R-RNO-8983063 https://reactome.org/PathwayBrowser/#/R-RNO-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Rattus norvegicus 30616 R-RNO-8983300 https://reactome.org/PathwayBrowser/#/R-RNO-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Rattus norvegicus 30616 R-RNO-8983371 https://reactome.org/PathwayBrowser/#/R-RNO-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Rattus norvegicus 30616 R-RNO-8983834 https://reactome.org/PathwayBrowser/#/R-RNO-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Rattus norvegicus 30616 R-RNO-8983835 https://reactome.org/PathwayBrowser/#/R-RNO-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Rattus norvegicus 30616 R-RNO-8983870 https://reactome.org/PathwayBrowser/#/R-RNO-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Rattus norvegicus 30616 R-RNO-8983872 https://reactome.org/PathwayBrowser/#/R-RNO-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Rattus norvegicus 30616 R-RNO-8984012 https://reactome.org/PathwayBrowser/#/R-RNO-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Rattus norvegicus 30616 R-RNO-8984014 https://reactome.org/PathwayBrowser/#/R-RNO-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Rattus norvegicus 30616 R-RNO-8985914 https://reactome.org/PathwayBrowser/#/R-RNO-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Rattus norvegicus 30616 R-RNO-8985973 https://reactome.org/PathwayBrowser/#/R-RNO-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Rattus norvegicus 30616 R-RNO-8985988 https://reactome.org/PathwayBrowser/#/R-RNO-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Rattus norvegicus 30616 R-RNO-8986985 https://reactome.org/PathwayBrowser/#/R-RNO-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Rattus norvegicus 30616 R-RNO-8986994 https://reactome.org/PathwayBrowser/#/R-RNO-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Rattus norvegicus 30616 R-RNO-8986995 https://reactome.org/PathwayBrowser/#/R-RNO-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Rattus norvegicus 30616 R-RNO-8987012 https://reactome.org/PathwayBrowser/#/R-RNO-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Rattus norvegicus 30616 R-RNO-8987040 https://reactome.org/PathwayBrowser/#/R-RNO-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Rattus norvegicus 30616 R-RNO-8987042 https://reactome.org/PathwayBrowser/#/R-RNO-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Rattus norvegicus 30616 R-RNO-8987070 https://reactome.org/PathwayBrowser/#/R-RNO-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Rattus norvegicus 30616 R-RNO-8987084 https://reactome.org/PathwayBrowser/#/R-RNO-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Rattus norvegicus 30616 R-RNO-8987096 https://reactome.org/PathwayBrowser/#/R-RNO-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Rattus norvegicus 30616 R-RNO-8987129 https://reactome.org/PathwayBrowser/#/R-RNO-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Rattus norvegicus 30616 R-RNO-8987141 https://reactome.org/PathwayBrowser/#/R-RNO-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Rattus norvegicus 30616 R-RNO-8987150 https://reactome.org/PathwayBrowser/#/R-RNO-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Rattus norvegicus 30616 R-RNO-8987179 https://reactome.org/PathwayBrowser/#/R-RNO-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Rattus norvegicus 30616 R-RNO-8987202 https://reactome.org/PathwayBrowser/#/R-RNO-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Rattus norvegicus 30616 R-RNO-8987255 https://reactome.org/PathwayBrowser/#/R-RNO-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Rattus norvegicus 30616 R-RNO-9006850 https://reactome.org/PathwayBrowser/#/R-RNO-9006850 IL21 receptor JAK phosphorylation IEA Rattus norvegicus 30616 R-RNO-9006870 https://reactome.org/PathwayBrowser/#/R-RNO-9006870 IL21 receptor STAT phosphorylation IEA Rattus norvegicus 30616 R-RNO-9007539 https://reactome.org/PathwayBrowser/#/R-RNO-9007539 CHEK1 phosphorylates E2F6 IEA Rattus norvegicus 30616 R-RNO-9008043 https://reactome.org/PathwayBrowser/#/R-RNO-9008043 MAPK8 phosphorylation IEA Rattus norvegicus 30616 R-RNO-9008684 https://reactome.org/PathwayBrowser/#/R-RNO-9008684 TBK1 phosphorylation IEA Rattus norvegicus 30616 R-RNO-9009072 https://reactome.org/PathwayBrowser/#/R-RNO-9009072 STAT3 phosphorylation IEA Rattus norvegicus 30616 R-RNO-9009936 https://reactome.org/PathwayBrowser/#/R-RNO-9009936 RNASEL cleaves cellular ssRNA IEA Rattus norvegicus 30616 R-RNO-9009950 https://reactome.org/PathwayBrowser/#/R-RNO-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Rattus norvegicus 30616 R-RNO-9012268 https://reactome.org/PathwayBrowser/#/R-RNO-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 30616 R-RNO-9012319 https://reactome.org/PathwayBrowser/#/R-RNO-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Rattus norvegicus 30616 R-RNO-9014741 https://reactome.org/PathwayBrowser/#/R-RNO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Rattus norvegicus 30616 R-RNO-9014766 https://reactome.org/PathwayBrowser/#/R-RNO-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Rattus norvegicus 30616 R-RNO-9018572 https://reactome.org/PathwayBrowser/#/R-RNO-9018572 EGFR phosphorylates NOTCH3 IEA Rattus norvegicus 30616 R-RNO-9021357 https://reactome.org/PathwayBrowser/#/R-RNO-9021357 PRKCI phosphorylates ELF3 IEA Rattus norvegicus 30616 R-RNO-9021609 https://reactome.org/PathwayBrowser/#/R-RNO-9021609 ESR-associated SRC autophosphorylates IEA Rattus norvegicus 30616 R-RNO-9021627 https://reactome.org/PathwayBrowser/#/R-RNO-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 30616 R-RNO-9027272 https://reactome.org/PathwayBrowser/#/R-RNO-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Rattus norvegicus 30616 R-RNO-9027273 https://reactome.org/PathwayBrowser/#/R-RNO-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Rattus norvegicus 30616 R-RNO-9030485 https://reactome.org/PathwayBrowser/#/R-RNO-9030485 Activated Ntrk2 phosphorylates Shc1 TAS Rattus norvegicus 30616 R-RNO-9032568 https://reactome.org/PathwayBrowser/#/R-RNO-9032568 Ntrk2-bound Fyn autophosphorylates TAS Rattus norvegicus 30616 R-RNO-9032619 https://reactome.org/PathwayBrowser/#/R-RNO-9032619 Fyn-mediated phosphorylation of Grin2b TAS Rattus norvegicus 30616 R-RNO-9033499 https://reactome.org/PathwayBrowser/#/R-RNO-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Rattus norvegicus 30616 R-RNO-9034714 https://reactome.org/PathwayBrowser/#/R-RNO-9034714 NTRK3 dimers trans-autophosphorylate IEA Rattus norvegicus 30616 R-RNO-9037056 https://reactome.org/PathwayBrowser/#/R-RNO-9037056 Src phosphorylates Ntrk2 TAS Rattus norvegicus 30616 R-RNO-9038161 https://reactome.org/PathwayBrowser/#/R-RNO-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Rattus norvegicus 30616 R-RNO-909552 https://reactome.org/PathwayBrowser/#/R-RNO-909552 Phosphorylation of STAT1 at Ser727 IEA Rattus norvegicus 30616 R-RNO-909718 https://reactome.org/PathwayBrowser/#/R-RNO-909718 Formation of p-STAT1 homodimer IEA Rattus norvegicus 30616 R-RNO-909729 https://reactome.org/PathwayBrowser/#/R-RNO-909729 Activation of JAK kinases IEA Rattus norvegicus 30616 R-RNO-909730 https://reactome.org/PathwayBrowser/#/R-RNO-909730 Phosphorylation of INFAR1 by TYK2 IEA Rattus norvegicus 30616 R-RNO-909732 https://reactome.org/PathwayBrowser/#/R-RNO-909732 Phosphorylation of STAT2 IEA Rattus norvegicus 30616 R-RNO-912527 https://reactome.org/PathwayBrowser/#/R-RNO-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Rattus norvegicus 30616 R-RNO-913996 https://reactome.org/PathwayBrowser/#/R-RNO-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Rattus norvegicus 30616 R-RNO-917693 https://reactome.org/PathwayBrowser/#/R-RNO-917693 ESCRT Disassembly IEA Rattus norvegicus 30616 R-RNO-917841 https://reactome.org/PathwayBrowser/#/R-RNO-917841 Acidification of Tf:TfR1 containing endosome IEA Rattus norvegicus 30616 R-RNO-917979 https://reactome.org/PathwayBrowser/#/R-RNO-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-927889 https://reactome.org/PathwayBrowser/#/R-RNO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Rattus norvegicus 30616 R-RNO-934559 https://reactome.org/PathwayBrowser/#/R-RNO-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Rattus norvegicus 30616 R-RNO-936802 https://reactome.org/PathwayBrowser/#/R-RNO-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Rattus norvegicus 30616 R-RNO-936883 https://reactome.org/PathwayBrowser/#/R-RNO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Rattus norvegicus 30616 R-RNO-936895 https://reactome.org/PathwayBrowser/#/R-RNO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Rattus norvegicus 30616 R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 30616 R-RNO-936951 https://reactome.org/PathwayBrowser/#/R-RNO-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Rattus norvegicus 30616 R-RNO-936991 https://reactome.org/PathwayBrowser/#/R-RNO-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Rattus norvegicus 30616 R-RNO-937034 https://reactome.org/PathwayBrowser/#/R-RNO-937034 IRAK1 phosphorylates Pellino IEA Rattus norvegicus 30616 R-RNO-937311 https://reactome.org/PathwayBrowser/#/R-RNO-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 30616 R-RNO-939763 https://reactome.org/PathwayBrowser/#/R-RNO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Rattus norvegicus 30616 R-RNO-947531 https://reactome.org/PathwayBrowser/#/R-RNO-947531 Molybdenum ion transfer onto molybdopterin IEA Rattus norvegicus 30616 R-RNO-947591 https://reactome.org/PathwayBrowser/#/R-RNO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Rattus norvegicus 30616 R-RNO-9603420 https://reactome.org/PathwayBrowser/#/R-RNO-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Rattus norvegicus 30616 R-RNO-9604328 https://reactome.org/PathwayBrowser/#/R-RNO-9604328 AKT1 phosphorylates NOTCH4 IEA Rattus norvegicus 30616 R-RNO-9606884 https://reactome.org/PathwayBrowser/#/R-RNO-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Rattus norvegicus 30616 R-RNO-9610153 https://reactome.org/PathwayBrowser/#/R-RNO-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Rattus norvegicus 30616 R-RNO-9610156 https://reactome.org/PathwayBrowser/#/R-RNO-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Rattus norvegicus 30616 R-RNO-9610163 https://reactome.org/PathwayBrowser/#/R-RNO-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Rattus norvegicus 30616 R-RNO-9612145 https://reactome.org/PathwayBrowser/#/R-RNO-9612145 Src phosphorylates GluN2 (Grin2) subunits of NMDARs TAS Rattus norvegicus 30616 R-RNO-9612501 https://reactome.org/PathwayBrowser/#/R-RNO-9612501 SGK phosphorylates CREB1 IEA Rattus norvegicus 30616 R-RNO-9612509 https://reactome.org/PathwayBrowser/#/R-RNO-9612509 SGK phosphorylates SRF IEA Rattus norvegicus 30616 R-RNO-9612988 https://reactome.org/PathwayBrowser/#/R-RNO-9612988 Rap1-GTP phosphorylates Raf1 TAS Rattus norvegicus 30616 R-RNO-9613024 https://reactome.org/PathwayBrowser/#/R-RNO-9613024 Ntrk1,2,3 in Adcyap1:Adcyap1r1:Ntrk1,2,3 autophosphorylates TAS Rattus norvegicus 30616 R-RNO-9613030 https://reactome.org/PathwayBrowser/#/R-RNO-9613030 Ntrk1,2,3 in Ade-Rib:Adora2a:Ntrk1,2,3 autophosphorylates TAS Rattus norvegicus 30616 R-RNO-9613494 https://reactome.org/PathwayBrowser/#/R-RNO-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Rattus norvegicus 30616 R-RNO-9617504 https://reactome.org/PathwayBrowser/#/R-RNO-9617504 Calmodulin-activated adenylate cyclases Adcy1 and Adcy8 generate cAMP TAS Rattus norvegicus 30616 R-RNO-9618616 https://reactome.org/PathwayBrowser/#/R-RNO-9618616 CaMKII autophosphorylates TAS Rattus norvegicus 30616 R-RNO-9619165 https://reactome.org/PathwayBrowser/#/R-RNO-9619165 Camkk1 phosphorylates Camk4 TAS Rattus norvegicus 30616 R-RNO-9619355 https://reactome.org/PathwayBrowser/#/R-RNO-9619355 CaMKK autophosphorylates in the cytosol IEA Rattus norvegicus 30616 R-RNO-9619772 https://reactome.org/PathwayBrowser/#/R-RNO-9619772 Camk1 phosphorylates Arhgef7 TAS Rattus norvegicus 30616 R-RNO-9620003 https://reactome.org/PathwayBrowser/#/R-RNO-9620003 Rps6ka1 autophosphorylates TAS Rattus norvegicus 30616 R-RNO-9620437 https://reactome.org/PathwayBrowser/#/R-RNO-9620437 Camk2 phosphorylates GluA1 (Gria1) TAS Rattus norvegicus 30616 R-RNO-9624526 https://reactome.org/PathwayBrowser/#/R-RNO-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Rattus norvegicus 30616 R-RNO-9624800 https://reactome.org/PathwayBrowser/#/R-RNO-9624800 CDK1 phosphorylates LBR IEA Rattus norvegicus 30616 R-RNO-9625487 https://reactome.org/PathwayBrowser/#/R-RNO-9625487 PTK2 autophosphorylates downstream of EGFR IEA Rattus norvegicus 30616 R-RNO-9626817 https://reactome.org/PathwayBrowser/#/R-RNO-9626817 PKC phosphorylates NCF1 IEA Rattus norvegicus 30616 R-RNO-9626832 https://reactome.org/PathwayBrowser/#/R-RNO-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Rattus norvegicus 30616 R-RNO-9626880 https://reactome.org/PathwayBrowser/#/R-RNO-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Rattus norvegicus 30616 R-RNO-9627056 https://reactome.org/PathwayBrowser/#/R-RNO-9627056 Procaspase 9 forms dimer IEA Rattus norvegicus 30616 R-RNO-9627089 https://reactome.org/PathwayBrowser/#/R-RNO-9627089 CASP9 is phosphorylated at T412 IEA Rattus norvegicus 30616 R-RNO-9632858 https://reactome.org/PathwayBrowser/#/R-RNO-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Rattus norvegicus 30616 R-RNO-9632868 https://reactome.org/PathwayBrowser/#/R-RNO-9632868 CDKN1B is phosphorylated in response to estrogen IEA Rattus norvegicus 30616 R-RNO-9634702 https://reactome.org/PathwayBrowser/#/R-RNO-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Rattus norvegicus 30616 R-RNO-9645442 https://reactome.org/PathwayBrowser/#/R-RNO-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Rattus norvegicus 30616 R-RNO-9645535 https://reactome.org/PathwayBrowser/#/R-RNO-9645535 ALPK1 phosphorylates TIFA IEA Rattus norvegicus 30616 R-RNO-964958 https://reactome.org/PathwayBrowser/#/R-RNO-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Rattus norvegicus 30616 R-RNO-964962 https://reactome.org/PathwayBrowser/#/R-RNO-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Rattus norvegicus 30616 R-RNO-964970 https://reactome.org/PathwayBrowser/#/R-RNO-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Rattus norvegicus 30616 R-RNO-9653503 https://reactome.org/PathwayBrowser/#/R-RNO-9653503 KRAS4B is phosphorylated on serine 181 IEA Rattus norvegicus 30616 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 30616 R-RNO-9661417 https://reactome.org/PathwayBrowser/#/R-RNO-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-9664221 https://reactome.org/PathwayBrowser/#/R-RNO-9664221 Atp2b1 (Pmca1) transports Ca2+ from the cytosol to the extracellular region TAS Rattus norvegicus 30616 R-RNO-9664232 https://reactome.org/PathwayBrowser/#/R-RNO-9664232 Atp2b2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region TAS Rattus norvegicus 30616 R-RNO-9668419 https://reactome.org/PathwayBrowser/#/R-RNO-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Rattus norvegicus 30616 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 30616 R-RNO-9684118 https://reactome.org/PathwayBrowser/#/R-RNO-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus 30616 R-RNO-9686521 https://reactome.org/PathwayBrowser/#/R-RNO-9686521 CDK2:CCNA phosphorylates TERF2 IEA Rattus norvegicus 30616 R-RNO-9687625 https://reactome.org/PathwayBrowser/#/R-RNO-9687625 ATP binds MLKL IEA Rattus norvegicus 30616 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 30616 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 30616 R-RNO-9699579 https://reactome.org/PathwayBrowser/#/R-RNO-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Rattus norvegicus 30616 R-RNO-9700168 https://reactome.org/PathwayBrowser/#/R-RNO-9700168 Active ALK phosphorylates IRS1 IEA Rattus norvegicus 30616 R-RNO-9700171 https://reactome.org/PathwayBrowser/#/R-RNO-9700171 Active ALK phosphorylates PLCG1 IEA Rattus norvegicus 30616 R-RNO-9700175 https://reactome.org/PathwayBrowser/#/R-RNO-9700175 Active ALK phosphorylates SHC1 IEA Rattus norvegicus 30616 R-RNO-9701488 https://reactome.org/PathwayBrowser/#/R-RNO-9701488 Active ALK phosphorylates JAK3 IEA Rattus norvegicus 30616 R-RNO-9705925 https://reactome.org/PathwayBrowser/#/R-RNO-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Rattus norvegicus 30616 R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 30616 R-RNO-9706390 https://reactome.org/PathwayBrowser/#/R-RNO-9706390 RHOBTB3 binds interacting proteins at trans-Golgi network IEA Rattus norvegicus 30616 R-RNO-9706393 https://reactome.org/PathwayBrowser/#/R-RNO-9706393 RHOBTB3 binds ATP IEA Rattus norvegicus 30616 R-RNO-9706399 https://reactome.org/PathwayBrowser/#/R-RNO-9706399 RHOBTB3 hydrolyzes ATP IEA Rattus norvegicus 30616 R-RNO-9706837 https://reactome.org/PathwayBrowser/#/R-RNO-9706837 AR binds AR antagonists IEA Rattus norvegicus 30616 R-RNO-9709547 https://reactome.org/PathwayBrowser/#/R-RNO-9709547 ESTG binds ESR2:chaperone complex IEA Rattus norvegicus 30616 R-RNO-9713735 https://reactome.org/PathwayBrowser/#/R-RNO-9713735 Adcy3:Gnal:GTP converts ATP to cAMP TAS Rattus norvegicus 30616 R-RNO-9716913 https://reactome.org/PathwayBrowser/#/R-RNO-9716913 ESR1 binds ESR1 antagonists IEA Rattus norvegicus 30616 R-RNO-9716947 https://reactome.org/PathwayBrowser/#/R-RNO-9716947 ESR1 binds ESR1 agonists IEA Rattus norvegicus 30616 R-RNO-9725855 https://reactome.org/PathwayBrowser/#/R-RNO-9725855 NR3C2 binds NR3C2 antagonists IEA Rattus norvegicus 30616 R-RNO-9725885 https://reactome.org/PathwayBrowser/#/R-RNO-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Rattus norvegicus 30616 R-RNO-9726509 https://reactome.org/PathwayBrowser/#/R-RNO-9726509 NR3C2 binds fludrocortisone IEA Rattus norvegicus 30616 R-RNO-9726580 https://reactome.org/PathwayBrowser/#/R-RNO-9726580 PGR binds PGR agonists IEA Rattus norvegicus 30616 R-RNO-9726621 https://reactome.org/PathwayBrowser/#/R-RNO-9726621 PGR binds PGR antagonists IEA Rattus norvegicus 30616 R-RNO-9727198 https://reactome.org/PathwayBrowser/#/R-RNO-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 30616 R-RNO-9731111 https://reactome.org/PathwayBrowser/#/R-RNO-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Rattus norvegicus 30616 R-RNO-9732738 https://reactome.org/PathwayBrowser/#/R-RNO-9732738 JAK1-mediated phosphorylation of RAF1 IEA Rattus norvegicus 30616 R-RNO-9732753 https://reactome.org/PathwayBrowser/#/R-RNO-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Rattus norvegicus 30616 R-RNO-9734535 https://reactome.org/PathwayBrowser/#/R-RNO-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Rattus norvegicus 30616 R-RNO-9734547 https://reactome.org/PathwayBrowser/#/R-RNO-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Rattus norvegicus 30616 R-RNO-9734687 https://reactome.org/PathwayBrowser/#/R-RNO-9734687 ORC6 is phosphorylated on T195 IEA Rattus norvegicus 30616 R-RNO-9748949 https://reactome.org/PathwayBrowser/#/R-RNO-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Rattus norvegicus 30616 R-RNO-9748957 https://reactome.org/PathwayBrowser/#/R-RNO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Rattus norvegicus 30616 R-RNO-9748963 https://reactome.org/PathwayBrowser/#/R-RNO-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Rattus norvegicus 30616 R-RNO-9748969 https://reactome.org/PathwayBrowser/#/R-RNO-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Rattus norvegicus 30616 R-RNO-9748999 https://reactome.org/PathwayBrowser/#/R-RNO-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Rattus norvegicus 30616 R-RNO-9749971 https://reactome.org/PathwayBrowser/#/R-RNO-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Rattus norvegicus 30616 R-RNO-9750546 https://reactome.org/PathwayBrowser/#/R-RNO-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-9750617 https://reactome.org/PathwayBrowser/#/R-RNO-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-9750656 https://reactome.org/PathwayBrowser/#/R-RNO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Rattus norvegicus 30616 R-RNO-975103 https://reactome.org/PathwayBrowser/#/R-RNO-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Rattus norvegicus 30616 R-RNO-975139 https://reactome.org/PathwayBrowser/#/R-RNO-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Rattus norvegicus 30616 R-RNO-9753278 https://reactome.org/PathwayBrowser/#/R-RNO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 30616 R-RNO-9753283 https://reactome.org/PathwayBrowser/#/R-RNO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 30616 R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 30616 R-RNO-9754974 https://reactome.org/PathwayBrowser/#/R-RNO-9754974 ADK phosphorylates RBV IEA Rattus norvegicus 30616 R-RNO-9755013 https://reactome.org/PathwayBrowser/#/R-RNO-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Rattus norvegicus 30616 R-RNO-9759454 https://reactome.org/PathwayBrowser/#/R-RNO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Rattus norvegicus 30616 R-RNO-9759461 https://reactome.org/PathwayBrowser/#/R-RNO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Rattus norvegicus 30616 R-RNO-9760094 https://reactome.org/PathwayBrowser/#/R-RNO-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Rattus norvegicus 30616 R-RNO-9762094 https://reactome.org/PathwayBrowser/#/R-RNO-9762094 GSK3B phosphorylates p-NFE2L2 IEA Rattus norvegicus 30616 R-RNO-9770141 https://reactome.org/PathwayBrowser/#/R-RNO-9770141 Formation of the Spliceosomal C* complex IEA Rattus norvegicus 30616 R-RNO-9770142 https://reactome.org/PathwayBrowser/#/R-RNO-9770142 Formation of the Spliceosomal B complex IEA Rattus norvegicus 30616 R-RNO-9773803 https://reactome.org/PathwayBrowser/#/R-RNO-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Rattus norvegicus 30616 R-RNO-9794120 https://reactome.org/PathwayBrowser/#/R-RNO-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Rattus norvegicus 30616 R-RNO-9794572 https://reactome.org/PathwayBrowser/#/R-RNO-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Rattus norvegicus 30616 R-RNO-9796053 https://reactome.org/PathwayBrowser/#/R-RNO-9796053 PRKCI phosphorylates NFE2L2 IEA Rattus norvegicus 30616 R-RNO-9796067 https://reactome.org/PathwayBrowser/#/R-RNO-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Rattus norvegicus 30616 R-RNO-9815501 https://reactome.org/PathwayBrowser/#/R-RNO-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 IEA Rattus norvegicus 30616 R-RNO-9817397 https://reactome.org/PathwayBrowser/#/R-RNO-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Rattus norvegicus 30616 R-RNO-9818789 https://reactome.org/PathwayBrowser/#/R-RNO-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Rattus norvegicus 30616 R-RNO-9819106 https://reactome.org/PathwayBrowser/#/R-RNO-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Rattus norvegicus 30616 R-RNO-9823906 https://reactome.org/PathwayBrowser/#/R-RNO-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Rattus norvegicus 30616 R-RNO-9824882 https://reactome.org/PathwayBrowser/#/R-RNO-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Rattus norvegicus 30616 R-RNO-9824977 https://reactome.org/PathwayBrowser/#/R-RNO-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Rattus norvegicus 30616 R-RNO-9824994 https://reactome.org/PathwayBrowser/#/R-RNO-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Rattus norvegicus 30616 R-RNO-9824995 https://reactome.org/PathwayBrowser/#/R-RNO-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Rattus norvegicus 30616 R-RNO-9824999 https://reactome.org/PathwayBrowser/#/R-RNO-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Rattus norvegicus 30616 R-RNO-9825759 https://reactome.org/PathwayBrowser/#/R-RNO-9825759 MAPK-dependent phosphorylation of KARS IEA Rattus norvegicus 30616 R-RNO-982807 https://reactome.org/PathwayBrowser/#/R-RNO-982807 JAK2 phosphorylation of GHR IEA Rattus norvegicus 30616 R-RNO-982810 https://reactome.org/PathwayBrowser/#/R-RNO-982810 JAK2 phosphorylation IEA Rattus norvegicus 30616 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus 30616 R-RNO-983144 https://reactome.org/PathwayBrowser/#/R-RNO-983144 Transport of Antigen peptide in to ER IEA Rattus norvegicus 30616 R-RNO-983153 https://reactome.org/PathwayBrowser/#/R-RNO-983153 E1 mediated ubiquitin activation IEA Rattus norvegicus 30616 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus 30616 R-RNO-983259 https://reactome.org/PathwayBrowser/#/R-RNO-983259 Kinesins move along microtubules consuming ATP IEA Rattus norvegicus 30616 R-RNO-9833973 https://reactome.org/PathwayBrowser/#/R-RNO-9833973 ISGylation of PKR IEA Rattus norvegicus 30616 R-RNO-9836159 https://reactome.org/PathwayBrowser/#/R-RNO-9836159 p-PKR dimer phosphorylates DHX9 IEA Rattus norvegicus 30616 R-RNO-9836184 https://reactome.org/PathwayBrowser/#/R-RNO-9836184 p-PKR dimer phosphorylates CDK1 IEA Rattus norvegicus 30616 R-RNO-9836322 https://reactome.org/PathwayBrowser/#/R-RNO-9836322 p-PKR dimer phosphorylates MKK6 IEA Rattus norvegicus 30616 R-RNO-9836362 https://reactome.org/PathwayBrowser/#/R-RNO-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Rattus norvegicus 30616 R-RNO-9836383 https://reactome.org/PathwayBrowser/#/R-RNO-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Rattus norvegicus 30616 R-RNO-9836404 https://reactome.org/PathwayBrowser/#/R-RNO-9836404 p-PKR dimer phosphorylates MAPT IEA Rattus norvegicus 30616 R-RNO-9836435 https://reactome.org/PathwayBrowser/#/R-RNO-9836435 p-PKR dimer phosphorylates SNCA IEA Rattus norvegicus 30616 R-RNO-9836515 https://reactome.org/PathwayBrowser/#/R-RNO-9836515 p-PKR dimer phosphorylates PTPN2 IEA Rattus norvegicus 30616 R-RNO-9836617 https://reactome.org/PathwayBrowser/#/R-RNO-9836617 p-PKR dimer phosphorylates SPHK1 IEA Rattus norvegicus 30616 R-RNO-9836664 https://reactome.org/PathwayBrowser/#/R-RNO-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Rattus norvegicus 30616 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus 30616 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus 30616 R-RNO-9837337 https://reactome.org/PathwayBrowser/#/R-RNO-9837337 DCAKD phosphorylates DP-CoA IEA Rattus norvegicus 30616 R-RNO-9838004 https://reactome.org/PathwayBrowser/#/R-RNO-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Rattus norvegicus 30616 R-RNO-9838081 https://reactome.org/PathwayBrowser/#/R-RNO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Rattus norvegicus 30616 R-RNO-9838289 https://reactome.org/PathwayBrowser/#/R-RNO-9838289 CLPXP degrades mitochondrial matrix proteins IEA Rattus norvegicus 30616 R-RNO-9838321 https://reactome.org/PathwayBrowser/#/R-RNO-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Rattus norvegicus 30616 R-RNO-9839059 https://reactome.org/PathwayBrowser/#/R-RNO-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Rattus norvegicus 30616 R-RNO-9839105 https://reactome.org/PathwayBrowser/#/R-RNO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Rattus norvegicus 30616 R-RNO-9839113 https://reactome.org/PathwayBrowser/#/R-RNO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Rattus norvegicus 30616 R-RNO-9840564 https://reactome.org/PathwayBrowser/#/R-RNO-9840564 OMA1 hydrolyzes YME1L1 IEA Rattus norvegicus 30616 R-RNO-9842648 https://reactome.org/PathwayBrowser/#/R-RNO-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 IEA Rattus norvegicus 30616 R-RNO-9842651 https://reactome.org/PathwayBrowser/#/R-RNO-9842651 Active LTK receptor phosphorylates SHC1 IEA Rattus norvegicus 30616 R-RNO-9842666 https://reactome.org/PathwayBrowser/#/R-RNO-9842666 Active LTK phosphorylates IRS1 IEA Rattus norvegicus 30616 R-RNO-9843721 https://reactome.org/PathwayBrowser/#/R-RNO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Rattus norvegicus 30616 R-RNO-9851972 https://reactome.org/PathwayBrowser/#/R-RNO-9851972 PLK1 phosphorylates FIRRM at S43 IEA Rattus norvegicus 30616 R-RNO-9853369 https://reactome.org/PathwayBrowser/#/R-RNO-9853369 PLK1 phosphorylates FIRMM at S744 IEA Rattus norvegicus 30616 R-RNO-9861642 https://reactome.org/PathwayBrowser/#/R-RNO-9861642 NEK1 phosphorylates ME1 IEA Rattus norvegicus 30616 R-RNO-994137 https://reactome.org/PathwayBrowser/#/R-RNO-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Rattus norvegicus 30616 R-RNO-994140 https://reactome.org/PathwayBrowser/#/R-RNO-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Rattus norvegicus 30616 R-SCE-109624 https://reactome.org/PathwayBrowser/#/R-SCE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Saccharomyces cerevisiae 30616 R-SCE-109702 https://reactome.org/PathwayBrowser/#/R-SCE-109702 PDPK1 phosphorylates AKT2 IEA Saccharomyces cerevisiae 30616 R-SCE-109860 https://reactome.org/PathwayBrowser/#/R-SCE-109860 MAP2K1 phosphorylates MAPK3 IEA Saccharomyces cerevisiae 30616 R-SCE-109862 https://reactome.org/PathwayBrowser/#/R-SCE-109862 MAP2K2 phosphorylates MAPK1 IEA Saccharomyces cerevisiae 30616 R-SCE-110133 https://reactome.org/PathwayBrowser/#/R-SCE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Saccharomyces cerevisiae 30616 R-SCE-110144 https://reactome.org/PathwayBrowser/#/R-SCE-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Saccharomyces cerevisiae 30616 R-SCE-110145 https://reactome.org/PathwayBrowser/#/R-SCE-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Saccharomyces cerevisiae 30616 R-SCE-111751 https://reactome.org/PathwayBrowser/#/R-SCE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 30616 R-SCE-111804 https://reactome.org/PathwayBrowser/#/R-SCE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 30616 R-SCE-111898 https://reactome.org/PathwayBrowser/#/R-SCE-111898 Phosphorylation of cPLA2 by ERK-2 IEA Saccharomyces cerevisiae 30616 R-SCE-114683 https://reactome.org/PathwayBrowser/#/R-SCE-114683 Phosphorylation of Platelet Sec-1 IEA Saccharomyces cerevisiae 30616 R-SCE-114684 https://reactome.org/PathwayBrowser/#/R-SCE-114684 Phosphorylation of Syntaxin-4 IEA Saccharomyces cerevisiae 30616 R-SCE-1247935 https://reactome.org/PathwayBrowser/#/R-SCE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Saccharomyces cerevisiae 30616 R-SCE-1252253 https://reactome.org/PathwayBrowser/#/R-SCE-1252253 TIM23 PAM complex translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix TAS Saccharomyces cerevisiae 30616 R-SCE-1454916 https://reactome.org/PathwayBrowser/#/R-SCE-1454916 The ABCC family mediates organic anion transport IEA Saccharomyces cerevisiae 30616 R-SCE-1454928 https://reactome.org/PathwayBrowser/#/R-SCE-1454928 ABCG4 may mediate cholesterol efflux IEA Saccharomyces cerevisiae 30616 R-SCE-1483004 https://reactome.org/PathwayBrowser/#/R-SCE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Saccharomyces cerevisiae 30616 R-SCE-1483222 https://reactome.org/PathwayBrowser/#/R-SCE-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Saccharomyces cerevisiae 30616 R-SCE-156678 https://reactome.org/PathwayBrowser/#/R-SCE-156678 Activation of Cdc25C IEA Saccharomyces cerevisiae 30616 R-SCE-156699 https://reactome.org/PathwayBrowser/#/R-SCE-156699 Inactivation of Wee1 kinase IEA Saccharomyces cerevisiae 30616 R-SCE-159425 https://reactome.org/PathwayBrowser/#/R-SCE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 30616 R-SCE-162657 https://reactome.org/PathwayBrowser/#/R-SCE-162657 Inactivation of Myt1 kinase IEA Saccharomyces cerevisiae 30616 R-SCE-163215 https://reactome.org/PathwayBrowser/#/R-SCE-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Saccharomyces cerevisiae 30616 R-SCE-164832 https://reactome.org/PathwayBrowser/#/R-SCE-164832 ATPase synthesizes ATP IEA Saccharomyces cerevisiae 30616 R-SCE-164834 https://reactome.org/PathwayBrowser/#/R-SCE-164834 Enzyme-bound ATP is released IEA Saccharomyces cerevisiae 30616 R-SCE-165726 https://reactome.org/PathwayBrowser/#/R-SCE-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Saccharomyces cerevisiae 30616 R-SCE-165766 https://reactome.org/PathwayBrowser/#/R-SCE-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Saccharomyces cerevisiae 30616 R-SCE-165777 https://reactome.org/PathwayBrowser/#/R-SCE-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Saccharomyces cerevisiae 30616 R-SCE-1675773 https://reactome.org/PathwayBrowser/#/R-SCE-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1675776 https://reactome.org/PathwayBrowser/#/R-SCE-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1675780 https://reactome.org/PathwayBrowser/#/R-SCE-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1675810 https://reactome.org/PathwayBrowser/#/R-SCE-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1675813 https://reactome.org/PathwayBrowser/#/R-SCE-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1675883 https://reactome.org/PathwayBrowser/#/R-SCE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1675939 https://reactome.org/PathwayBrowser/#/R-SCE-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1675961 https://reactome.org/PathwayBrowser/#/R-SCE-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1675974 https://reactome.org/PathwayBrowser/#/R-SCE-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1676024 https://reactome.org/PathwayBrowser/#/R-SCE-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1676082 https://reactome.org/PathwayBrowser/#/R-SCE-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1676134 https://reactome.org/PathwayBrowser/#/R-SCE-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1676145 https://reactome.org/PathwayBrowser/#/R-SCE-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Saccharomyces cerevisiae 30616 R-SCE-1676185 https://reactome.org/PathwayBrowser/#/R-SCE-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Saccharomyces cerevisiae 30616 R-SCE-168053 https://reactome.org/PathwayBrowser/#/R-SCE-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Saccharomyces cerevisiae 30616 R-SCE-168136 https://reactome.org/PathwayBrowser/#/R-SCE-168136 Activated JNKs phosphorylate c-JUN IEA Saccharomyces cerevisiae 30616 R-SCE-174389 https://reactome.org/PathwayBrowser/#/R-SCE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Saccharomyces cerevisiae 30616 R-SCE-174391 https://reactome.org/PathwayBrowser/#/R-SCE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Saccharomyces cerevisiae 30616 R-SCE-174392 https://reactome.org/PathwayBrowser/#/R-SCE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Saccharomyces cerevisiae 30616 R-SCE-174394 https://reactome.org/PathwayBrowser/#/R-SCE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Saccharomyces cerevisiae 30616 R-SCE-1855157 https://reactome.org/PathwayBrowser/#/R-SCE-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 30616 R-SCE-1855158 https://reactome.org/PathwayBrowser/#/R-SCE-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-1855181 https://reactome.org/PathwayBrowser/#/R-SCE-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 30616 R-SCE-1855182 https://reactome.org/PathwayBrowser/#/R-SCE-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-1855193 https://reactome.org/PathwayBrowser/#/R-SCE-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-1855194 https://reactome.org/PathwayBrowser/#/R-SCE-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-1855207 https://reactome.org/PathwayBrowser/#/R-SCE-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 30616 R-SCE-1855216 https://reactome.org/PathwayBrowser/#/R-SCE-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-1855223 https://reactome.org/PathwayBrowser/#/R-SCE-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-1855224 https://reactome.org/PathwayBrowser/#/R-SCE-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 30616 R-SCE-1855227 https://reactome.org/PathwayBrowser/#/R-SCE-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-1855230 https://reactome.org/PathwayBrowser/#/R-SCE-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 30616 R-SCE-191380 https://reactome.org/PathwayBrowser/#/R-SCE-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Saccharomyces cerevisiae 30616 R-SCE-191414 https://reactome.org/PathwayBrowser/#/R-SCE-191414 MVD decarboxylates MVA5PP to IPPP IEA Saccharomyces cerevisiae 30616 R-SCE-192137 https://reactome.org/PathwayBrowser/#/R-SCE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 30616 R-SCE-193401 https://reactome.org/PathwayBrowser/#/R-SCE-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 30616 R-SCE-193407 https://reactome.org/PathwayBrowser/#/R-SCE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 30616 R-SCE-193424 https://reactome.org/PathwayBrowser/#/R-SCE-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 30616 R-SCE-193711 https://reactome.org/PathwayBrowser/#/R-SCE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 30616 R-SCE-193727 https://reactome.org/PathwayBrowser/#/R-SCE-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 30616 R-SCE-193743 https://reactome.org/PathwayBrowser/#/R-SCE-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 30616 R-SCE-193766 https://reactome.org/PathwayBrowser/#/R-SCE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 30616 R-SCE-194153 https://reactome.org/PathwayBrowser/#/R-SCE-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Saccharomyces cerevisiae 30616 R-SCE-196753 https://reactome.org/PathwayBrowser/#/R-SCE-196753 2xPPCS ligates PPanK with Cys IEA Saccharomyces cerevisiae 30616 R-SCE-196754 https://reactome.org/PathwayBrowser/#/R-SCE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Saccharomyces cerevisiae 30616 R-SCE-196761 https://reactome.org/PathwayBrowser/#/R-SCE-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Saccharomyces cerevisiae 30616 R-SCE-196773 https://reactome.org/PathwayBrowser/#/R-SCE-196773 COASY phosphorylates DP-CoA IEA Saccharomyces cerevisiae 30616 R-SCE-196929 https://reactome.org/PathwayBrowser/#/R-SCE-196929 FLAD1 phosphorylates FMN IEA Saccharomyces cerevisiae 30616 R-SCE-196964 https://reactome.org/PathwayBrowser/#/R-SCE-196964 RFK:Mg2+ phosphorylates RIB IEA Saccharomyces cerevisiae 30616 R-SCE-197198 https://reactome.org/PathwayBrowser/#/R-SCE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Saccharomyces cerevisiae 30616 R-SCE-197235 https://reactome.org/PathwayBrowser/#/R-SCE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 30616 R-SCE-197271 https://reactome.org/PathwayBrowser/#/R-SCE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Saccharomyces cerevisiae 30616 R-SCE-197958 https://reactome.org/PathwayBrowser/#/R-SCE-197958 FPGS-2 transforms THF to THFPG IEA Saccharomyces cerevisiae 30616 R-SCE-198314 https://reactome.org/PathwayBrowser/#/R-SCE-198314 DAG stimulates protein kinase C-delta IEA Saccharomyces cerevisiae 30616 R-SCE-198640 https://reactome.org/PathwayBrowser/#/R-SCE-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Saccharomyces cerevisiae 30616 R-SCE-198669 https://reactome.org/PathwayBrowser/#/R-SCE-198669 p38MAPK phosphorylates MSK1 IEA Saccharomyces cerevisiae 30616 R-SCE-198746 https://reactome.org/PathwayBrowser/#/R-SCE-198746 ERK1/2/5 activate RSK1/2/3 IEA Saccharomyces cerevisiae 30616 R-SCE-198756 https://reactome.org/PathwayBrowser/#/R-SCE-198756 ERK1/2 phosphorylates MSK1 IEA Saccharomyces cerevisiae 30616 R-SCE-199839 https://reactome.org/PathwayBrowser/#/R-SCE-199839 AKT can phosphorylate RSK IEA Saccharomyces cerevisiae 30616 R-SCE-200423 https://reactome.org/PathwayBrowser/#/R-SCE-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Saccharomyces cerevisiae 30616 R-SCE-200474 https://reactome.org/PathwayBrowser/#/R-SCE-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 30616 R-SCE-200512 https://reactome.org/PathwayBrowser/#/R-SCE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 30616 R-SCE-200555 https://reactome.org/PathwayBrowser/#/R-SCE-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Saccharomyces cerevisiae 30616 R-SCE-200681 https://reactome.org/PathwayBrowser/#/R-SCE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Saccharomyces cerevisiae 30616 R-SCE-200682 https://reactome.org/PathwayBrowser/#/R-SCE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Saccharomyces cerevisiae 30616 R-SCE-200711 https://reactome.org/PathwayBrowser/#/R-SCE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Saccharomyces cerevisiae 30616 R-SCE-201035 https://reactome.org/PathwayBrowser/#/R-SCE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Saccharomyces cerevisiae 30616 R-SCE-202111 https://reactome.org/PathwayBrowser/#/R-SCE-202111 AKT1 phosphorylates eNOS IEA Saccharomyces cerevisiae 30616 R-SCE-202222 https://reactome.org/PathwayBrowser/#/R-SCE-202222 Phosphorylation of PKC theta IEA Saccharomyces cerevisiae 30616 R-SCE-2029454 https://reactome.org/PathwayBrowser/#/R-SCE-2029454 Autophosphorylation of PAK1 IEA Saccharomyces cerevisiae 30616 R-SCE-2029473 https://reactome.org/PathwayBrowser/#/R-SCE-2029473 Branching and elongation of mother and daughter filaments IEA Saccharomyces cerevisiae 30616 R-SCE-2046087 https://reactome.org/PathwayBrowser/#/R-SCE-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Saccharomyces cerevisiae 30616 R-SCE-2046093 https://reactome.org/PathwayBrowser/#/R-SCE-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Saccharomyces cerevisiae 30616 R-SCE-2168079 https://reactome.org/PathwayBrowser/#/R-SCE-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Saccharomyces cerevisiae 30616 R-SCE-2214351 https://reactome.org/PathwayBrowser/#/R-SCE-2214351 PLK1 phosphorylates GORASP1 IEA Saccharomyces cerevisiae 30616 R-SCE-2408551 https://reactome.org/PathwayBrowser/#/R-SCE-2408551 SeMet is converted to AdoSeMet by MAT IEA Saccharomyces cerevisiae 30616 R-SCE-2430535 https://reactome.org/PathwayBrowser/#/R-SCE-2430535 MASTL phosphorylates ENSA IEA Saccharomyces cerevisiae 30616 R-SCE-2466068 https://reactome.org/PathwayBrowser/#/R-SCE-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Saccharomyces cerevisiae 30616 R-SCE-2529020 https://reactome.org/PathwayBrowser/#/R-SCE-2529020 CK2 phosphorylates condensin I subunits IEA Saccharomyces cerevisiae 30616 R-SCE-265783 https://reactome.org/PathwayBrowser/#/R-SCE-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Saccharomyces cerevisiae 30616 R-SCE-266082 https://reactome.org/PathwayBrowser/#/R-SCE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Saccharomyces cerevisiae 30616 R-SCE-2730835 https://reactome.org/PathwayBrowser/#/R-SCE-2730835 Autophosphorylation of PKC-theta IEA Saccharomyces cerevisiae 30616 R-SCE-2990833 https://reactome.org/PathwayBrowser/#/R-SCE-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Saccharomyces cerevisiae 30616 R-SCE-2993802 https://reactome.org/PathwayBrowser/#/R-SCE-2993802 HLCS biotinylates PC:Mn2+ IEA Saccharomyces cerevisiae 30616 R-SCE-2993814 https://reactome.org/PathwayBrowser/#/R-SCE-2993814 HLCS biotinylates ACACA:Mn2+ IEA Saccharomyces cerevisiae 30616 R-SCE-3095901 https://reactome.org/PathwayBrowser/#/R-SCE-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Saccharomyces cerevisiae 30616 R-SCE-3371422 https://reactome.org/PathwayBrowser/#/R-SCE-3371422 ATP hydrolysis by HSP70 IEA Saccharomyces cerevisiae 30616 R-SCE-3371435 https://reactome.org/PathwayBrowser/#/R-SCE-3371435 Constitutive phosphorylation by GSK3 IEA Saccharomyces cerevisiae 30616 R-SCE-3371531 https://reactome.org/PathwayBrowser/#/R-SCE-3371531 Constitutive phosphorylation by pERK1/2 IEA Saccharomyces cerevisiae 30616 R-SCE-3371590 https://reactome.org/PathwayBrowser/#/R-SCE-3371590 HSP70 binds to HSP40:nascent protein IEA Saccharomyces cerevisiae 30616 R-SCE-381091 https://reactome.org/PathwayBrowser/#/R-SCE-381091 IRE1 dimer autophosphorylates IEA Saccharomyces cerevisiae 30616 R-SCE-382560 https://reactome.org/PathwayBrowser/#/R-SCE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Saccharomyces cerevisiae 30616 R-SCE-382575 https://reactome.org/PathwayBrowser/#/R-SCE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Saccharomyces cerevisiae 30616 R-SCE-389622 https://reactome.org/PathwayBrowser/#/R-SCE-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 30616 R-SCE-389632 https://reactome.org/PathwayBrowser/#/R-SCE-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 30616 R-SCE-389756 https://reactome.org/PathwayBrowser/#/R-SCE-389756 AKT interacts and phosphorylates Cot IEA Saccharomyces cerevisiae 30616 R-SCE-392530 https://reactome.org/PathwayBrowser/#/R-SCE-392530 p-S400-Cot phosphorylates NIK IEA Saccharomyces cerevisiae 30616 R-SCE-4167511 https://reactome.org/PathwayBrowser/#/R-SCE-4167511 HLCS biotinylates ACACB IEA Saccharomyces cerevisiae 30616 R-SCE-428273 https://reactome.org/PathwayBrowser/#/R-SCE-428273 SPHK1 phosphorylates sphingoid IEA Saccharomyces cerevisiae 30616 R-SCE-428941 https://reactome.org/PathwayBrowser/#/R-SCE-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Saccharomyces cerevisiae 30616 R-SCE-428961 https://reactome.org/PathwayBrowser/#/R-SCE-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Saccharomyces cerevisiae 30616 R-SCE-434382 https://reactome.org/PathwayBrowser/#/R-SCE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Saccharomyces cerevisiae 30616 R-SCE-445079 https://reactome.org/PathwayBrowser/#/R-SCE-445079 Phosphorylation of L1 by ERK IEA Saccharomyces cerevisiae 30616 R-SCE-448955 https://reactome.org/PathwayBrowser/#/R-SCE-448955 Phosphorylation of MEF2 proteins by p38 IEA Saccharomyces cerevisiae 30616 R-SCE-449911 https://reactome.org/PathwayBrowser/#/R-SCE-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Saccharomyces cerevisiae 30616 R-SCE-450088 https://reactome.org/PathwayBrowser/#/R-SCE-450088 GLUT1 tetramer binds 4xATP IEA Saccharomyces cerevisiae 30616 R-SCE-450092 https://reactome.org/PathwayBrowser/#/R-SCE-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Saccharomyces cerevisiae 30616 R-SCE-450490 https://reactome.org/PathwayBrowser/#/R-SCE-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Saccharomyces cerevisiae 30616 R-SCE-453342 https://reactome.org/PathwayBrowser/#/R-SCE-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Saccharomyces cerevisiae 30616 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 30616 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 30616 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 30616 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 30616 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 30616 R-SCE-504054 https://reactome.org/PathwayBrowser/#/R-SCE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Saccharomyces cerevisiae 30616 R-SCE-508040 https://reactome.org/PathwayBrowser/#/R-SCE-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Saccharomyces cerevisiae 30616 R-SCE-5082405 https://reactome.org/PathwayBrowser/#/R-SCE-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Saccharomyces cerevisiae 30616 R-SCE-5218805 https://reactome.org/PathwayBrowser/#/R-SCE-5218805 PKC autophosphorylates IEA Saccharomyces cerevisiae 30616 R-SCE-5218821 https://reactome.org/PathwayBrowser/#/R-SCE-5218821 PDK1 phosphorylates PKC IEA Saccharomyces cerevisiae 30616 R-SCE-5218823 https://reactome.org/PathwayBrowser/#/R-SCE-5218823 PKC phosphorylates sphingosine kinase 1 IEA Saccharomyces cerevisiae 30616 R-SCE-5251942 https://reactome.org/PathwayBrowser/#/R-SCE-5251942 Hikeshi binds HSP70s:ATP IEA Saccharomyces cerevisiae 30616 R-SCE-5251955 https://reactome.org/PathwayBrowser/#/R-SCE-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Saccharomyces cerevisiae 30616 R-SCE-5251959 https://reactome.org/PathwayBrowser/#/R-SCE-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-5251989 https://reactome.org/PathwayBrowser/#/R-SCE-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-5252041 https://reactome.org/PathwayBrowser/#/R-SCE-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Saccharomyces cerevisiae 30616 R-SCE-5252079 https://reactome.org/PathwayBrowser/#/R-SCE-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Saccharomyces cerevisiae 30616 R-SCE-5339524 https://reactome.org/PathwayBrowser/#/R-SCE-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-5358475 https://reactome.org/PathwayBrowser/#/R-SCE-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Saccharomyces cerevisiae 30616 R-SCE-5358510 https://reactome.org/PathwayBrowser/#/R-SCE-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Saccharomyces cerevisiae 30616 R-SCE-5358518 https://reactome.org/PathwayBrowser/#/R-SCE-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Saccharomyces cerevisiae 30616 R-SCE-5358592 https://reactome.org/PathwayBrowser/#/R-SCE-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Saccharomyces cerevisiae 30616 R-SCE-5358597 https://reactome.org/PathwayBrowser/#/R-SCE-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Saccharomyces cerevisiae 30616 R-SCE-5358912 https://reactome.org/PathwayBrowser/#/R-SCE-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Saccharomyces cerevisiae 30616 R-SCE-548843 https://reactome.org/PathwayBrowser/#/R-SCE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Saccharomyces cerevisiae 30616 R-SCE-5618107 https://reactome.org/PathwayBrowser/#/R-SCE-5618107 ATP binding to HSP90 triggers conformation change IEA Saccharomyces cerevisiae 30616 R-SCE-5623667 https://reactome.org/PathwayBrowser/#/R-SCE-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Saccharomyces cerevisiae 30616 R-SCE-5625784 https://reactome.org/PathwayBrowser/#/R-SCE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 30616 R-SCE-5626507 https://reactome.org/PathwayBrowser/#/R-SCE-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Saccharomyces cerevisiae 30616 R-SCE-5627775 https://reactome.org/PathwayBrowser/#/R-SCE-5627775 Autophosphorylation of PAK1,2,3 IEA Saccharomyces cerevisiae 30616 R-SCE-5654989 https://reactome.org/PathwayBrowser/#/R-SCE-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Saccharomyces cerevisiae 30616 R-SCE-5662466 https://reactome.org/PathwayBrowser/#/R-SCE-5662466 XYLB phosphorylates D-xylulose IEA Saccharomyces cerevisiae 30616 R-SCE-5665868 https://reactome.org/PathwayBrowser/#/R-SCE-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Saccharomyces cerevisiae 30616 R-SCE-5668545 https://reactome.org/PathwayBrowser/#/R-SCE-5668545 NIK autophosphorylates on T559 IEA Saccharomyces cerevisiae 30616 R-SCE-5668932 https://reactome.org/PathwayBrowser/#/R-SCE-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Saccharomyces cerevisiae 30616 R-SCE-5671749 https://reactome.org/PathwayBrowser/#/R-SCE-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Saccharomyces cerevisiae 30616 R-SCE-5672008 https://reactome.org/PathwayBrowser/#/R-SCE-5672008 Thr-180 of ULK1 is phosphorylated IEA Saccharomyces cerevisiae 30616 R-SCE-5672012 https://reactome.org/PathwayBrowser/#/R-SCE-5672012 Beclin-1 complex phosphorylates PtdIns IEA Saccharomyces cerevisiae 30616 R-SCE-5674373 https://reactome.org/PathwayBrowser/#/R-SCE-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Saccharomyces cerevisiae 30616 R-SCE-5674496 https://reactome.org/PathwayBrowser/#/R-SCE-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Saccharomyces cerevisiae 30616 R-SCE-5675868 https://reactome.org/PathwayBrowser/#/R-SCE-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Saccharomyces cerevisiae 30616 R-SCE-5679041 https://reactome.org/PathwayBrowser/#/R-SCE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 30616 R-SCE-5679205 https://reactome.org/PathwayBrowser/#/R-SCE-5679205 ULK1 phosphorylates Beclin-1 IEA Saccharomyces cerevisiae 30616 R-SCE-5682026 https://reactome.org/PathwayBrowser/#/R-SCE-5682026 MRN bound to shortened telomeres activates ATM IEA Saccharomyces cerevisiae 30616 R-SCE-5682598 https://reactome.org/PathwayBrowser/#/R-SCE-5682598 ATM phosphorylates HERC2 IEA Saccharomyces cerevisiae 30616 R-SCE-5682983 https://reactome.org/PathwayBrowser/#/R-SCE-5682983 ATM phosphorylates WHSC1 IEA Saccharomyces cerevisiae 30616 R-SCE-5683425 https://reactome.org/PathwayBrowser/#/R-SCE-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Saccharomyces cerevisiae 30616 R-SCE-5683792 https://reactome.org/PathwayBrowser/#/R-SCE-5683792 p-T68-CHEK2 autophosphorylates IEA Saccharomyces cerevisiae 30616 R-SCE-5685230 https://reactome.org/PathwayBrowser/#/R-SCE-5685230 CHEK1 phosphorylates RAD51 IEA Saccharomyces cerevisiae 30616 R-SCE-5687086 https://reactome.org/PathwayBrowser/#/R-SCE-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Saccharomyces cerevisiae 30616 R-SCE-5692462 https://reactome.org/PathwayBrowser/#/R-SCE-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Saccharomyces cerevisiae 30616 R-SCE-5692480 https://reactome.org/PathwayBrowser/#/R-SCE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Saccharomyces cerevisiae 30616 R-SCE-5693536 https://reactome.org/PathwayBrowser/#/R-SCE-5693536 ATM phosphorylates MDC1 IEA Saccharomyces cerevisiae 30616 R-SCE-5693540 https://reactome.org/PathwayBrowser/#/R-SCE-5693540 MRN activates ATM IEA Saccharomyces cerevisiae 30616 R-SCE-5693549 https://reactome.org/PathwayBrowser/#/R-SCE-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Saccharomyces cerevisiae 30616 R-SCE-5693598 https://reactome.org/PathwayBrowser/#/R-SCE-5693598 ATM phosphorylates NBN IEA Saccharomyces cerevisiae 30616 R-SCE-5694425 https://reactome.org/PathwayBrowser/#/R-SCE-5694425 NSF ATPase activity dissociates cis-SNARE IEA Saccharomyces cerevisiae 30616 R-SCE-5694441 https://reactome.org/PathwayBrowser/#/R-SCE-5694441 CSNK1D phosphorylates SEC23 IEA Saccharomyces cerevisiae 30616 R-SCE-5696074 https://reactome.org/PathwayBrowser/#/R-SCE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Saccharomyces cerevisiae 30616 R-SCE-5696839 https://reactome.org/PathwayBrowser/#/R-SCE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Saccharomyces cerevisiae 30616 R-SCE-6782131 https://reactome.org/PathwayBrowser/#/R-SCE-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Saccharomyces cerevisiae 30616 R-SCE-6788798 https://reactome.org/PathwayBrowser/#/R-SCE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 30616 R-SCE-6788810 https://reactome.org/PathwayBrowser/#/R-SCE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 30616 R-SCE-6795290 https://reactome.org/PathwayBrowser/#/R-SCE-6795290 TORC2 complex phosphorylates SGK1 IEA Saccharomyces cerevisiae 30616 R-SCE-6795473 https://reactome.org/PathwayBrowser/#/R-SCE-6795473 PDPK1 phosphorylates SGK1 IEA Saccharomyces cerevisiae 30616 R-SCE-6797606 https://reactome.org/PathwayBrowser/#/R-SCE-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Saccharomyces cerevisiae 30616 R-SCE-6798174 https://reactome.org/PathwayBrowser/#/R-SCE-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Saccharomyces cerevisiae 30616 R-SCE-6801342 https://reactome.org/PathwayBrowser/#/R-SCE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Saccharomyces cerevisiae 30616 R-SCE-6801456 https://reactome.org/PathwayBrowser/#/R-SCE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Saccharomyces cerevisiae 30616 R-SCE-6802973 https://reactome.org/PathwayBrowser/#/R-SCE-6802973 PLK3 phosphorylates CDC25C IEA Saccharomyces cerevisiae 30616 R-SCE-6806877 https://reactome.org/PathwayBrowser/#/R-SCE-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Saccharomyces cerevisiae 30616 R-SCE-6806967 https://reactome.org/PathwayBrowser/#/R-SCE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Saccharomyces cerevisiae 30616 R-SCE-6807868 https://reactome.org/PathwayBrowser/#/R-SCE-6807868 GBF1 stimulates ARF nucleotide exchange IEA Saccharomyces cerevisiae 30616 R-SCE-6809015 https://reactome.org/PathwayBrowser/#/R-SCE-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Saccharomyces cerevisiae 30616 R-SCE-6810233 https://reactome.org/PathwayBrowser/#/R-SCE-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Saccharomyces cerevisiae 30616 R-SCE-6811422 https://reactome.org/PathwayBrowser/#/R-SCE-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Saccharomyces cerevisiae 30616 R-SCE-6811522 https://reactome.org/PathwayBrowser/#/R-SCE-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Saccharomyces cerevisiae 30616 R-SCE-6814120 https://reactome.org/PathwayBrowser/#/R-SCE-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Saccharomyces cerevisiae 30616 R-SCE-6814124 https://reactome.org/PathwayBrowser/#/R-SCE-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Saccharomyces cerevisiae 30616 R-SCE-68610 https://reactome.org/PathwayBrowser/#/R-SCE-68610 Formation of ORC(2-5) complex IEA Saccharomyces cerevisiae 30616 R-SCE-68954 https://reactome.org/PathwayBrowser/#/R-SCE-68954 Mcm2-7 is phosphorylated by DDK IEA Saccharomyces cerevisiae 30616 R-SCE-69063 https://reactome.org/PathwayBrowser/#/R-SCE-69063 Loading of PCNA - Sliding Clamp Formation IEA Saccharomyces cerevisiae 30616 R-SCE-69604 https://reactome.org/PathwayBrowser/#/R-SCE-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Saccharomyces cerevisiae 30616 R-SCE-69608 https://reactome.org/PathwayBrowser/#/R-SCE-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Saccharomyces cerevisiae 30616 R-SCE-70349 https://reactome.org/PathwayBrowser/#/R-SCE-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Saccharomyces cerevisiae 30616 R-SCE-70420 https://reactome.org/PathwayBrowser/#/R-SCE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Saccharomyces cerevisiae 30616 R-SCE-70467 https://reactome.org/PathwayBrowser/#/R-SCE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 30616 R-SCE-70486 https://reactome.org/PathwayBrowser/#/R-SCE-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Saccharomyces cerevisiae 30616 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 30616 R-SCE-70555 https://reactome.org/PathwayBrowser/#/R-SCE-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Saccharomyces cerevisiae 30616 R-SCE-70599 https://reactome.org/PathwayBrowser/#/R-SCE-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Saccharomyces cerevisiae 30616 R-SCE-70606 https://reactome.org/PathwayBrowser/#/R-SCE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Saccharomyces cerevisiae 30616 R-SCE-70967 https://reactome.org/PathwayBrowser/#/R-SCE-70967 IDH3 complex decarboxylates isocitrate IEA Saccharomyces cerevisiae 30616 R-SCE-70997 https://reactome.org/PathwayBrowser/#/R-SCE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Saccharomyces cerevisiae 30616 R-SCE-71401 https://reactome.org/PathwayBrowser/#/R-SCE-71401 OGDH dimer decarboxylates 2-OG IEA Saccharomyces cerevisiae 30616 R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 30616 R-SCE-71735 https://reactome.org/PathwayBrowser/#/R-SCE-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Saccharomyces cerevisiae 30616 R-SCE-71802 https://reactome.org/PathwayBrowser/#/R-SCE-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 30616 R-SCE-71850 https://reactome.org/PathwayBrowser/#/R-SCE-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Saccharomyces cerevisiae 30616 R-SCE-72621 https://reactome.org/PathwayBrowser/#/R-SCE-72621 Ribosomal scanning IEA Saccharomyces cerevisiae 30616 R-SCE-72647 https://reactome.org/PathwayBrowser/#/R-SCE-72647 Cap-bound mRNA is activated by helicases IEA Saccharomyces cerevisiae 30616 R-SCE-73548 https://reactome.org/PathwayBrowser/#/R-SCE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Saccharomyces cerevisiae 30616 R-SCE-73577 https://reactome.org/PathwayBrowser/#/R-SCE-73577 CAD hexamer transforms L-Gln to CAP IEA Saccharomyces cerevisiae 30616 R-SCE-73580 https://reactome.org/PathwayBrowser/#/R-SCE-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Saccharomyces cerevisiae 30616 R-SCE-73635 https://reactome.org/PathwayBrowser/#/R-SCE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Saccharomyces cerevisiae 30616 R-SCE-73647 https://reactome.org/PathwayBrowser/#/R-SCE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Saccharomyces cerevisiae 30616 R-SCE-73788 https://reactome.org/PathwayBrowser/#/R-SCE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Saccharomyces cerevisiae 30616 R-SCE-73792 https://reactome.org/PathwayBrowser/#/R-SCE-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Saccharomyces cerevisiae 30616 R-SCE-73810 https://reactome.org/PathwayBrowser/#/R-SCE-73810 FGAM + ATP => AIR + ADP + Pi IEA Saccharomyces cerevisiae 30616 R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 30616 R-SCE-73814 https://reactome.org/PathwayBrowser/#/R-SCE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Saccharomyces cerevisiae 30616 R-SCE-75010 https://reactome.org/PathwayBrowser/#/R-SCE-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Saccharomyces cerevisiae 30616 R-SCE-75125 https://reactome.org/PathwayBrowser/#/R-SCE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Saccharomyces cerevisiae 30616 R-SCE-75126 https://reactome.org/PathwayBrowser/#/R-SCE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Saccharomyces cerevisiae 30616 R-SCE-75809 https://reactome.org/PathwayBrowser/#/R-SCE-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Saccharomyces cerevisiae 30616 R-SCE-75851 https://reactome.org/PathwayBrowser/#/R-SCE-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 30616 R-SCE-75887 https://reactome.org/PathwayBrowser/#/R-SCE-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Saccharomyces cerevisiae 30616 R-SCE-75949 https://reactome.org/PathwayBrowser/#/R-SCE-75949 RNA Polymerase II Promoter Opening: First Transition IEA Saccharomyces cerevisiae 30616 R-SCE-77071 https://reactome.org/PathwayBrowser/#/R-SCE-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Saccharomyces cerevisiae 30616 R-SCE-8847638 https://reactome.org/PathwayBrowser/#/R-SCE-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Saccharomyces cerevisiae 30616 R-SCE-8850945 https://reactome.org/PathwayBrowser/#/R-SCE-8850945 Casein kinase II phosphorylates PTEN IEA Saccharomyces cerevisiae 30616 R-SCE-8852128 https://reactome.org/PathwayBrowser/#/R-SCE-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Saccharomyces cerevisiae 30616 R-SCE-8852131 https://reactome.org/PathwayBrowser/#/R-SCE-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Saccharomyces cerevisiae 30616 R-SCE-8852132 https://reactome.org/PathwayBrowser/#/R-SCE-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-8852134 https://reactome.org/PathwayBrowser/#/R-SCE-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Saccharomyces cerevisiae 30616 R-SCE-8856813 https://reactome.org/PathwayBrowser/#/R-SCE-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Saccharomyces cerevisiae 30616 R-SCE-8868066 https://reactome.org/PathwayBrowser/#/R-SCE-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Saccharomyces cerevisiae 30616 R-SCE-8876889 https://reactome.org/PathwayBrowser/#/R-SCE-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 30616 R-SCE-8939959 https://reactome.org/PathwayBrowser/#/R-SCE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Saccharomyces cerevisiae 30616 R-SCE-8948039 https://reactome.org/PathwayBrowser/#/R-SCE-8948039 FUNDC1 is phosphorylated by CK2 IEA Saccharomyces cerevisiae 30616 R-SCE-8948146 https://reactome.org/PathwayBrowser/#/R-SCE-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Saccharomyces cerevisiae 30616 R-SCE-8951648 https://reactome.org/PathwayBrowser/#/R-SCE-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Saccharomyces cerevisiae 30616 R-SCE-8951656 https://reactome.org/PathwayBrowser/#/R-SCE-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Saccharomyces cerevisiae 30616 R-SCE-8954327 https://reactome.org/PathwayBrowser/#/R-SCE-8954327 UCKL1 phosphorylates urindine, cytidine IEA Saccharomyces cerevisiae 30616 R-SCE-8955844 https://reactome.org/PathwayBrowser/#/R-SCE-8955844 RBKS phosphorylates ribose to R5P IEA Saccharomyces cerevisiae 30616 R-SCE-9008043 https://reactome.org/PathwayBrowser/#/R-SCE-9008043 MAPK8 phosphorylation IEA Saccharomyces cerevisiae 30616 R-SCE-9012319 https://reactome.org/PathwayBrowser/#/R-SCE-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Saccharomyces cerevisiae 30616 R-SCE-9014741 https://reactome.org/PathwayBrowser/#/R-SCE-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Saccharomyces cerevisiae 30616 R-SCE-9014766 https://reactome.org/PathwayBrowser/#/R-SCE-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Saccharomyces cerevisiae 30616 R-SCE-9033756 https://reactome.org/PathwayBrowser/#/R-SCE-9033756 PEX1:PEX6:PEX15:Ub:PEX5:PEX14:PEX13:PEX17:PEX1:PEX6:PEX15 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX17:PEX1:PEX6:PEX15 TAS Saccharomyces cerevisiae 30616 R-SCE-917693 https://reactome.org/PathwayBrowser/#/R-SCE-917693 ESCRT Disassembly IEA Saccharomyces cerevisiae 30616 R-SCE-917841 https://reactome.org/PathwayBrowser/#/R-SCE-917841 Acidification of Tf:TfR1 containing endosome IEA Saccharomyces cerevisiae 30616 R-SCE-917979 https://reactome.org/PathwayBrowser/#/R-SCE-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Saccharomyces cerevisiae 30616 R-SCE-927889 https://reactome.org/PathwayBrowser/#/R-SCE-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Saccharomyces cerevisiae 30616 R-SCE-936883 https://reactome.org/PathwayBrowser/#/R-SCE-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Saccharomyces cerevisiae 30616 R-SCE-936895 https://reactome.org/PathwayBrowser/#/R-SCE-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Saccharomyces cerevisiae 30616 R-SCE-939763 https://reactome.org/PathwayBrowser/#/R-SCE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Saccharomyces cerevisiae 30616 R-SCE-947591 https://reactome.org/PathwayBrowser/#/R-SCE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Saccharomyces cerevisiae 30616 R-SCE-9606884 https://reactome.org/PathwayBrowser/#/R-SCE-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Saccharomyces cerevisiae 30616 R-SCE-9612509 https://reactome.org/PathwayBrowser/#/R-SCE-9612509 SGK phosphorylates SRF IEA Saccharomyces cerevisiae 30616 R-SCE-9613494 https://reactome.org/PathwayBrowser/#/R-SCE-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Saccharomyces cerevisiae 30616 R-SCE-9626817 https://reactome.org/PathwayBrowser/#/R-SCE-9626817 PKC phosphorylates NCF1 IEA Saccharomyces cerevisiae 30616 R-SCE-9628640 https://reactome.org/PathwayBrowser/#/R-SCE-9628640 SBH1:GET3:ADP:GET1:GET2 dissociates yielding SBH1 in the endoplasmic reticulum membrane TAS Saccharomyces cerevisiae 30616 R-SCE-9629050 https://reactome.org/PathwayBrowser/#/R-SCE-9629050 SBH1:GET3:ATP:GET4:MDY2:SGT2 dissociates and GET3 hydrolyzes ATP yielding SBH1:GET3:ADP TAS Saccharomyces cerevisiae 30616 R-SCE-9632858 https://reactome.org/PathwayBrowser/#/R-SCE-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Saccharomyces cerevisiae 30616 R-SCE-9633480 https://reactome.org/PathwayBrowser/#/R-SCE-9633480 GCN2 phosphorylates SUI2 TAS Saccharomyces cerevisiae 30616 R-SCE-9633750 https://reactome.org/PathwayBrowser/#/R-SCE-9633750 GCN2 dimer autophosphorylates TAS Saccharomyces cerevisiae 30616 R-SCE-964958 https://reactome.org/PathwayBrowser/#/R-SCE-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Saccharomyces cerevisiae 30616 R-SCE-964962 https://reactome.org/PathwayBrowser/#/R-SCE-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Saccharomyces cerevisiae 30616 R-SCE-964970 https://reactome.org/PathwayBrowser/#/R-SCE-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Saccharomyces cerevisiae 30616 R-SCE-9661417 https://reactome.org/PathwayBrowser/#/R-SCE-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 30616 R-SCE-9684118 https://reactome.org/PathwayBrowser/#/R-SCE-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Saccharomyces cerevisiae 30616 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 30616 R-SCE-9734535 https://reactome.org/PathwayBrowser/#/R-SCE-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Saccharomyces cerevisiae 30616 R-SCE-9748949 https://reactome.org/PathwayBrowser/#/R-SCE-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Saccharomyces cerevisiae 30616 R-SCE-9748957 https://reactome.org/PathwayBrowser/#/R-SCE-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Saccharomyces cerevisiae 30616 R-SCE-9748963 https://reactome.org/PathwayBrowser/#/R-SCE-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Saccharomyces cerevisiae 30616 R-SCE-9748969 https://reactome.org/PathwayBrowser/#/R-SCE-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Saccharomyces cerevisiae 30616 R-SCE-9748999 https://reactome.org/PathwayBrowser/#/R-SCE-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Saccharomyces cerevisiae 30616 R-SCE-9749381 https://reactome.org/PathwayBrowser/#/R-SCE-9749381 ATP-dependent release of CDT1 from the OCCM complex in budding yeast TAS Saccharomyces cerevisiae 30616 R-SCE-9750656 https://reactome.org/PathwayBrowser/#/R-SCE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Saccharomyces cerevisiae 30616 R-SCE-9753278 https://reactome.org/PathwayBrowser/#/R-SCE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 30616 R-SCE-9753283 https://reactome.org/PathwayBrowser/#/R-SCE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 30616 R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 30616 R-SCE-9754974 https://reactome.org/PathwayBrowser/#/R-SCE-9754974 ADK phosphorylates RBV IEA Saccharomyces cerevisiae 30616 R-SCE-9755013 https://reactome.org/PathwayBrowser/#/R-SCE-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Saccharomyces cerevisiae 30616 R-SCE-9760094 https://reactome.org/PathwayBrowser/#/R-SCE-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Saccharomyces cerevisiae 30616 R-SCE-9794120 https://reactome.org/PathwayBrowser/#/R-SCE-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Saccharomyces cerevisiae 30616 R-SCE-9794572 https://reactome.org/PathwayBrowser/#/R-SCE-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Saccharomyces cerevisiae 30616 R-SCE-9824977 https://reactome.org/PathwayBrowser/#/R-SCE-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Saccharomyces cerevisiae 30616 R-SCE-9824994 https://reactome.org/PathwayBrowser/#/R-SCE-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Saccharomyces cerevisiae 30616 R-SCE-9824995 https://reactome.org/PathwayBrowser/#/R-SCE-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Saccharomyces cerevisiae 30616 R-SCE-9824999 https://reactome.org/PathwayBrowser/#/R-SCE-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Saccharomyces cerevisiae 30616 R-SCE-983140 https://reactome.org/PathwayBrowser/#/R-SCE-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Saccharomyces cerevisiae 30616 R-SCE-983153 https://reactome.org/PathwayBrowser/#/R-SCE-983153 E1 mediated ubiquitin activation IEA Saccharomyces cerevisiae 30616 R-SCE-983156 https://reactome.org/PathwayBrowser/#/R-SCE-983156 Polyubiquitination of substrate IEA Saccharomyces cerevisiae 30616 R-SCE-9837337 https://reactome.org/PathwayBrowser/#/R-SCE-9837337 DCAKD phosphorylates DP-CoA IEA Saccharomyces cerevisiae 30616 R-SCE-9838004 https://reactome.org/PathwayBrowser/#/R-SCE-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 30616 R-SCE-9838081 https://reactome.org/PathwayBrowser/#/R-SCE-9838081 LONP1 degrades mitochondrial matrix proteins IEA Saccharomyces cerevisiae 30616 R-SCE-9838321 https://reactome.org/PathwayBrowser/#/R-SCE-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Saccharomyces cerevisiae 30616 R-SCE-9839105 https://reactome.org/PathwayBrowser/#/R-SCE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Saccharomyces cerevisiae 30616 R-SCE-9839113 https://reactome.org/PathwayBrowser/#/R-SCE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 30616 R-SCE-9839836 https://reactome.org/PathwayBrowser/#/R-SCE-9839836 YME1 degrades TIM10 TAS Saccharomyces cerevisiae 30616 R-SCE-9840564 https://reactome.org/PathwayBrowser/#/R-SCE-9840564 OMA1 hydrolyzes YME1L1 IEA Saccharomyces cerevisiae 30616 R-SCE-9843721 https://reactome.org/PathwayBrowser/#/R-SCE-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Saccharomyces cerevisiae 30616 R-SPO-109624 https://reactome.org/PathwayBrowser/#/R-SPO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Schizosaccharomyces pombe 30616 R-SPO-109702 https://reactome.org/PathwayBrowser/#/R-SPO-109702 PDPK1 phosphorylates AKT2 IEA Schizosaccharomyces pombe 30616 R-SPO-109860 https://reactome.org/PathwayBrowser/#/R-SPO-109860 MAP2K1 phosphorylates MAPK3 IEA Schizosaccharomyces pombe 30616 R-SPO-109862 https://reactome.org/PathwayBrowser/#/R-SPO-109862 MAP2K2 phosphorylates MAPK1 IEA Schizosaccharomyces pombe 30616 R-SPO-110133 https://reactome.org/PathwayBrowser/#/R-SPO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Schizosaccharomyces pombe 30616 R-SPO-110144 https://reactome.org/PathwayBrowser/#/R-SPO-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Schizosaccharomyces pombe 30616 R-SPO-110145 https://reactome.org/PathwayBrowser/#/R-SPO-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Schizosaccharomyces pombe 30616 R-SPO-111751 https://reactome.org/PathwayBrowser/#/R-SPO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 30616 R-SPO-111804 https://reactome.org/PathwayBrowser/#/R-SPO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 30616 R-SPO-111898 https://reactome.org/PathwayBrowser/#/R-SPO-111898 Phosphorylation of cPLA2 by ERK-2 IEA Schizosaccharomyces pombe 30616 R-SPO-114683 https://reactome.org/PathwayBrowser/#/R-SPO-114683 Phosphorylation of Platelet Sec-1 IEA Schizosaccharomyces pombe 30616 R-SPO-114684 https://reactome.org/PathwayBrowser/#/R-SPO-114684 Phosphorylation of Syntaxin-4 IEA Schizosaccharomyces pombe 30616 R-SPO-1247935 https://reactome.org/PathwayBrowser/#/R-SPO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Schizosaccharomyces pombe 30616 R-SPO-1358791 https://reactome.org/PathwayBrowser/#/R-SPO-1358791 Phosphorylation of USP8 by P-AKT IEA Schizosaccharomyces pombe 30616 R-SPO-1369065 https://reactome.org/PathwayBrowser/#/R-SPO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Schizosaccharomyces pombe 30616 R-SPO-1454916 https://reactome.org/PathwayBrowser/#/R-SPO-1454916 The ABCC family mediates organic anion transport IEA Schizosaccharomyces pombe 30616 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 30616 R-SPO-1483004 https://reactome.org/PathwayBrowser/#/R-SPO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Schizosaccharomyces pombe 30616 R-SPO-1483222 https://reactome.org/PathwayBrowser/#/R-SPO-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Schizosaccharomyces pombe 30616 R-SPO-156678 https://reactome.org/PathwayBrowser/#/R-SPO-156678 Activation of Cdc25C IEA Schizosaccharomyces pombe 30616 R-SPO-156682 https://reactome.org/PathwayBrowser/#/R-SPO-156682 PLK1 phosphorylates NUDC IEA Schizosaccharomyces pombe 30616 R-SPO-156699 https://reactome.org/PathwayBrowser/#/R-SPO-156699 Inactivation of Wee1 kinase IEA Schizosaccharomyces pombe 30616 R-SPO-162657 https://reactome.org/PathwayBrowser/#/R-SPO-162657 Inactivation of Myt1 kinase IEA Schizosaccharomyces pombe 30616 R-SPO-163215 https://reactome.org/PathwayBrowser/#/R-SPO-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1632857 https://reactome.org/PathwayBrowser/#/R-SPO-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Schizosaccharomyces pombe 30616 R-SPO-165162 https://reactome.org/PathwayBrowser/#/R-SPO-165162 Phosphorylation of TSC2 by PKB IEA Schizosaccharomyces pombe 30616 R-SPO-165182 https://reactome.org/PathwayBrowser/#/R-SPO-165182 Phosphorylation of complexed TSC2 by PKB IEA Schizosaccharomyces pombe 30616 R-SPO-165726 https://reactome.org/PathwayBrowser/#/R-SPO-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Schizosaccharomyces pombe 30616 R-SPO-165766 https://reactome.org/PathwayBrowser/#/R-SPO-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Schizosaccharomyces pombe 30616 R-SPO-165777 https://reactome.org/PathwayBrowser/#/R-SPO-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Schizosaccharomyces pombe 30616 R-SPO-1675773 https://reactome.org/PathwayBrowser/#/R-SPO-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1675776 https://reactome.org/PathwayBrowser/#/R-SPO-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1675780 https://reactome.org/PathwayBrowser/#/R-SPO-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1675810 https://reactome.org/PathwayBrowser/#/R-SPO-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1675813 https://reactome.org/PathwayBrowser/#/R-SPO-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1675883 https://reactome.org/PathwayBrowser/#/R-SPO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1675939 https://reactome.org/PathwayBrowser/#/R-SPO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1675961 https://reactome.org/PathwayBrowser/#/R-SPO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1675974 https://reactome.org/PathwayBrowser/#/R-SPO-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1676024 https://reactome.org/PathwayBrowser/#/R-SPO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1676082 https://reactome.org/PathwayBrowser/#/R-SPO-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1676134 https://reactome.org/PathwayBrowser/#/R-SPO-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1676145 https://reactome.org/PathwayBrowser/#/R-SPO-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Schizosaccharomyces pombe 30616 R-SPO-1676185 https://reactome.org/PathwayBrowser/#/R-SPO-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Schizosaccharomyces pombe 30616 R-SPO-168053 https://reactome.org/PathwayBrowser/#/R-SPO-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Schizosaccharomyces pombe 30616 R-SPO-174164 https://reactome.org/PathwayBrowser/#/R-SPO-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Schizosaccharomyces pombe 30616 R-SPO-174367 https://reactome.org/PathwayBrowser/#/R-SPO-174367 GCL ligates L-Glu to L-Cys IEA Schizosaccharomyces pombe 30616 R-SPO-174389 https://reactome.org/PathwayBrowser/#/R-SPO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Schizosaccharomyces pombe 30616 R-SPO-174391 https://reactome.org/PathwayBrowser/#/R-SPO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Schizosaccharomyces pombe 30616 R-SPO-174392 https://reactome.org/PathwayBrowser/#/R-SPO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Schizosaccharomyces pombe 30616 R-SPO-174394 https://reactome.org/PathwayBrowser/#/R-SPO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Schizosaccharomyces pombe 30616 R-SPO-1855157 https://reactome.org/PathwayBrowser/#/R-SPO-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 30616 R-SPO-1855158 https://reactome.org/PathwayBrowser/#/R-SPO-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-1855181 https://reactome.org/PathwayBrowser/#/R-SPO-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 30616 R-SPO-1855182 https://reactome.org/PathwayBrowser/#/R-SPO-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-1855193 https://reactome.org/PathwayBrowser/#/R-SPO-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-1855194 https://reactome.org/PathwayBrowser/#/R-SPO-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-1855207 https://reactome.org/PathwayBrowser/#/R-SPO-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 30616 R-SPO-1855216 https://reactome.org/PathwayBrowser/#/R-SPO-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-1855223 https://reactome.org/PathwayBrowser/#/R-SPO-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-1855224 https://reactome.org/PathwayBrowser/#/R-SPO-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 30616 R-SPO-1855227 https://reactome.org/PathwayBrowser/#/R-SPO-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-1855230 https://reactome.org/PathwayBrowser/#/R-SPO-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 30616 R-SPO-187948 https://reactome.org/PathwayBrowser/#/R-SPO-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Schizosaccharomyces pombe 30616 R-SPO-187949 https://reactome.org/PathwayBrowser/#/R-SPO-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Schizosaccharomyces pombe 30616 R-SPO-191380 https://reactome.org/PathwayBrowser/#/R-SPO-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Schizosaccharomyces pombe 30616 R-SPO-191414 https://reactome.org/PathwayBrowser/#/R-SPO-191414 MVD decarboxylates MVA5PP to IPPP IEA Schizosaccharomyces pombe 30616 R-SPO-193362 https://reactome.org/PathwayBrowser/#/R-SPO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 30616 R-SPO-194153 https://reactome.org/PathwayBrowser/#/R-SPO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 30616 R-SPO-196753 https://reactome.org/PathwayBrowser/#/R-SPO-196753 2xPPCS ligates PPanK with Cys IEA Schizosaccharomyces pombe 30616 R-SPO-196754 https://reactome.org/PathwayBrowser/#/R-SPO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Schizosaccharomyces pombe 30616 R-SPO-196761 https://reactome.org/PathwayBrowser/#/R-SPO-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Schizosaccharomyces pombe 30616 R-SPO-196773 https://reactome.org/PathwayBrowser/#/R-SPO-196773 COASY phosphorylates DP-CoA IEA Schizosaccharomyces pombe 30616 R-SPO-196929 https://reactome.org/PathwayBrowser/#/R-SPO-196929 FLAD1 phosphorylates FMN IEA Schizosaccharomyces pombe 30616 R-SPO-196964 https://reactome.org/PathwayBrowser/#/R-SPO-196964 RFK:Mg2+ phosphorylates RIB IEA Schizosaccharomyces pombe 30616 R-SPO-197198 https://reactome.org/PathwayBrowser/#/R-SPO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Schizosaccharomyces pombe 30616 R-SPO-197235 https://reactome.org/PathwayBrowser/#/R-SPO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 30616 R-SPO-197271 https://reactome.org/PathwayBrowser/#/R-SPO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Schizosaccharomyces pombe 30616 R-SPO-197958 https://reactome.org/PathwayBrowser/#/R-SPO-197958 FPGS-2 transforms THF to THFPG IEA Schizosaccharomyces pombe 30616 R-SPO-198314 https://reactome.org/PathwayBrowser/#/R-SPO-198314 DAG stimulates protein kinase C-delta IEA Schizosaccharomyces pombe 30616 R-SPO-198609 https://reactome.org/PathwayBrowser/#/R-SPO-198609 AKT phosphorylates TSC2, inhibiting it IEA Schizosaccharomyces pombe 30616 R-SPO-198640 https://reactome.org/PathwayBrowser/#/R-SPO-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Schizosaccharomyces pombe 30616 R-SPO-198669 https://reactome.org/PathwayBrowser/#/R-SPO-198669 p38MAPK phosphorylates MSK1 IEA Schizosaccharomyces pombe 30616 R-SPO-198746 https://reactome.org/PathwayBrowser/#/R-SPO-198746 ERK1/2/5 activate RSK1/2/3 IEA Schizosaccharomyces pombe 30616 R-SPO-198756 https://reactome.org/PathwayBrowser/#/R-SPO-198756 ERK1/2 phosphorylates MSK1 IEA Schizosaccharomyces pombe 30616 R-SPO-199839 https://reactome.org/PathwayBrowser/#/R-SPO-199839 AKT can phosphorylate RSK IEA Schizosaccharomyces pombe 30616 R-SPO-200423 https://reactome.org/PathwayBrowser/#/R-SPO-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Schizosaccharomyces pombe 30616 R-SPO-200474 https://reactome.org/PathwayBrowser/#/R-SPO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 30616 R-SPO-200512 https://reactome.org/PathwayBrowser/#/R-SPO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 30616 R-SPO-200555 https://reactome.org/PathwayBrowser/#/R-SPO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Schizosaccharomyces pombe 30616 R-SPO-200681 https://reactome.org/PathwayBrowser/#/R-SPO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Schizosaccharomyces pombe 30616 R-SPO-200682 https://reactome.org/PathwayBrowser/#/R-SPO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Schizosaccharomyces pombe 30616 R-SPO-200711 https://reactome.org/PathwayBrowser/#/R-SPO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Schizosaccharomyces pombe 30616 R-SPO-201035 https://reactome.org/PathwayBrowser/#/R-SPO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Schizosaccharomyces pombe 30616 R-SPO-202111 https://reactome.org/PathwayBrowser/#/R-SPO-202111 AKT1 phosphorylates eNOS IEA Schizosaccharomyces pombe 30616 R-SPO-202222 https://reactome.org/PathwayBrowser/#/R-SPO-202222 Phosphorylation of PKC theta IEA Schizosaccharomyces pombe 30616 R-SPO-2029454 https://reactome.org/PathwayBrowser/#/R-SPO-2029454 Autophosphorylation of PAK1 IEA Schizosaccharomyces pombe 30616 R-SPO-2029473 https://reactome.org/PathwayBrowser/#/R-SPO-2029473 Branching and elongation of mother and daughter filaments IEA Schizosaccharomyces pombe 30616 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 30616 R-SPO-2168079 https://reactome.org/PathwayBrowser/#/R-SPO-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Schizosaccharomyces pombe 30616 R-SPO-2214351 https://reactome.org/PathwayBrowser/#/R-SPO-2214351 PLK1 phosphorylates GORASP1 IEA Schizosaccharomyces pombe 30616 R-SPO-2408551 https://reactome.org/PathwayBrowser/#/R-SPO-2408551 SeMet is converted to AdoSeMet by MAT IEA Schizosaccharomyces pombe 30616 R-SPO-2430535 https://reactome.org/PathwayBrowser/#/R-SPO-2430535 MASTL phosphorylates ENSA IEA Schizosaccharomyces pombe 30616 R-SPO-2466068 https://reactome.org/PathwayBrowser/#/R-SPO-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Schizosaccharomyces pombe 30616 R-SPO-2529020 https://reactome.org/PathwayBrowser/#/R-SPO-2529020 CK2 phosphorylates condensin I subunits IEA Schizosaccharomyces pombe 30616 R-SPO-2730835 https://reactome.org/PathwayBrowser/#/R-SPO-2730835 Autophosphorylation of PKC-theta IEA Schizosaccharomyces pombe 30616 R-SPO-2990833 https://reactome.org/PathwayBrowser/#/R-SPO-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Schizosaccharomyces pombe 30616 R-SPO-2993802 https://reactome.org/PathwayBrowser/#/R-SPO-2993802 HLCS biotinylates PC:Mn2+ IEA Schizosaccharomyces pombe 30616 R-SPO-2993814 https://reactome.org/PathwayBrowser/#/R-SPO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Schizosaccharomyces pombe 30616 R-SPO-3095901 https://reactome.org/PathwayBrowser/#/R-SPO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Schizosaccharomyces pombe 30616 R-SPO-3371422 https://reactome.org/PathwayBrowser/#/R-SPO-3371422 ATP hydrolysis by HSP70 IEA Schizosaccharomyces pombe 30616 R-SPO-3371435 https://reactome.org/PathwayBrowser/#/R-SPO-3371435 Constitutive phosphorylation by GSK3 IEA Schizosaccharomyces pombe 30616 R-SPO-3371531 https://reactome.org/PathwayBrowser/#/R-SPO-3371531 Constitutive phosphorylation by pERK1/2 IEA Schizosaccharomyces pombe 30616 R-SPO-3371590 https://reactome.org/PathwayBrowser/#/R-SPO-3371590 HSP70 binds to HSP40:nascent protein IEA Schizosaccharomyces pombe 30616 R-SPO-380927 https://reactome.org/PathwayBrowser/#/R-SPO-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Schizosaccharomyces pombe 30616 R-SPO-381091 https://reactome.org/PathwayBrowser/#/R-SPO-381091 IRE1 dimer autophosphorylates IEA Schizosaccharomyces pombe 30616 R-SPO-382560 https://reactome.org/PathwayBrowser/#/R-SPO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Schizosaccharomyces pombe 30616 R-SPO-4167511 https://reactome.org/PathwayBrowser/#/R-SPO-4167511 HLCS biotinylates ACACB IEA Schizosaccharomyces pombe 30616 R-SPO-428273 https://reactome.org/PathwayBrowser/#/R-SPO-428273 SPHK1 phosphorylates sphingoid IEA Schizosaccharomyces pombe 30616 R-SPO-428941 https://reactome.org/PathwayBrowser/#/R-SPO-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Schizosaccharomyces pombe 30616 R-SPO-428961 https://reactome.org/PathwayBrowser/#/R-SPO-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Schizosaccharomyces pombe 30616 R-SPO-434382 https://reactome.org/PathwayBrowser/#/R-SPO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Schizosaccharomyces pombe 30616 R-SPO-442749 https://reactome.org/PathwayBrowser/#/R-SPO-442749 CaMKK autophosphorylates in the nucleus IEA Schizosaccharomyces pombe 30616 R-SPO-445079 https://reactome.org/PathwayBrowser/#/R-SPO-445079 Phosphorylation of L1 by ERK IEA Schizosaccharomyces pombe 30616 R-SPO-448955 https://reactome.org/PathwayBrowser/#/R-SPO-448955 Phosphorylation of MEF2 proteins by p38 IEA Schizosaccharomyces pombe 30616 R-SPO-449911 https://reactome.org/PathwayBrowser/#/R-SPO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Schizosaccharomyces pombe 30616 R-SPO-450490 https://reactome.org/PathwayBrowser/#/R-SPO-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Schizosaccharomyces pombe 30616 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 30616 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 30616 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 30616 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 30616 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 30616 R-SPO-504054 https://reactome.org/PathwayBrowser/#/R-SPO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Schizosaccharomyces pombe 30616 R-SPO-508040 https://reactome.org/PathwayBrowser/#/R-SPO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Schizosaccharomyces pombe 30616 R-SPO-5082405 https://reactome.org/PathwayBrowser/#/R-SPO-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Schizosaccharomyces pombe 30616 R-SPO-5218805 https://reactome.org/PathwayBrowser/#/R-SPO-5218805 PKC autophosphorylates IEA Schizosaccharomyces pombe 30616 R-SPO-5218821 https://reactome.org/PathwayBrowser/#/R-SPO-5218821 PDK1 phosphorylates PKC IEA Schizosaccharomyces pombe 30616 R-SPO-5218823 https://reactome.org/PathwayBrowser/#/R-SPO-5218823 PKC phosphorylates sphingosine kinase 1 IEA Schizosaccharomyces pombe 30616 R-SPO-5223317 https://reactome.org/PathwayBrowser/#/R-SPO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 30616 R-SPO-5251942 https://reactome.org/PathwayBrowser/#/R-SPO-5251942 Hikeshi binds HSP70s:ATP IEA Schizosaccharomyces pombe 30616 R-SPO-5251955 https://reactome.org/PathwayBrowser/#/R-SPO-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Schizosaccharomyces pombe 30616 R-SPO-5251959 https://reactome.org/PathwayBrowser/#/R-SPO-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-5251989 https://reactome.org/PathwayBrowser/#/R-SPO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-5252041 https://reactome.org/PathwayBrowser/#/R-SPO-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Schizosaccharomyces pombe 30616 R-SPO-5252079 https://reactome.org/PathwayBrowser/#/R-SPO-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Schizosaccharomyces pombe 30616 R-SPO-5358475 https://reactome.org/PathwayBrowser/#/R-SPO-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Schizosaccharomyces pombe 30616 R-SPO-5358510 https://reactome.org/PathwayBrowser/#/R-SPO-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Schizosaccharomyces pombe 30616 R-SPO-5358518 https://reactome.org/PathwayBrowser/#/R-SPO-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Schizosaccharomyces pombe 30616 R-SPO-5358592 https://reactome.org/PathwayBrowser/#/R-SPO-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Schizosaccharomyces pombe 30616 R-SPO-5358597 https://reactome.org/PathwayBrowser/#/R-SPO-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Schizosaccharomyces pombe 30616 R-SPO-5358599 https://reactome.org/PathwayBrowser/#/R-SPO-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Schizosaccharomyces pombe 30616 R-SPO-5358912 https://reactome.org/PathwayBrowser/#/R-SPO-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Schizosaccharomyces pombe 30616 R-SPO-548843 https://reactome.org/PathwayBrowser/#/R-SPO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Schizosaccharomyces pombe 30616 R-SPO-5618107 https://reactome.org/PathwayBrowser/#/R-SPO-5618107 ATP binding to HSP90 triggers conformation change IEA Schizosaccharomyces pombe 30616 R-SPO-5623667 https://reactome.org/PathwayBrowser/#/R-SPO-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Schizosaccharomyces pombe 30616 R-SPO-5625784 https://reactome.org/PathwayBrowser/#/R-SPO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 30616 R-SPO-5626507 https://reactome.org/PathwayBrowser/#/R-SPO-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Schizosaccharomyces pombe 30616 R-SPO-5627775 https://reactome.org/PathwayBrowser/#/R-SPO-5627775 Autophosphorylation of PAK1,2,3 IEA Schizosaccharomyces pombe 30616 R-SPO-5654989 https://reactome.org/PathwayBrowser/#/R-SPO-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Schizosaccharomyces pombe 30616 R-SPO-5662466 https://reactome.org/PathwayBrowser/#/R-SPO-5662466 XYLB phosphorylates D-xylulose IEA Schizosaccharomyces pombe 30616 R-SPO-5665868 https://reactome.org/PathwayBrowser/#/R-SPO-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Schizosaccharomyces pombe 30616 R-SPO-5668932 https://reactome.org/PathwayBrowser/#/R-SPO-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Schizosaccharomyces pombe 30616 R-SPO-5671749 https://reactome.org/PathwayBrowser/#/R-SPO-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Schizosaccharomyces pombe 30616 R-SPO-5672008 https://reactome.org/PathwayBrowser/#/R-SPO-5672008 Thr-180 of ULK1 is phosphorylated IEA Schizosaccharomyces pombe 30616 R-SPO-5672012 https://reactome.org/PathwayBrowser/#/R-SPO-5672012 Beclin-1 complex phosphorylates PtdIns IEA Schizosaccharomyces pombe 30616 R-SPO-5674373 https://reactome.org/PathwayBrowser/#/R-SPO-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Schizosaccharomyces pombe 30616 R-SPO-5674496 https://reactome.org/PathwayBrowser/#/R-SPO-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Schizosaccharomyces pombe 30616 R-SPO-5675868 https://reactome.org/PathwayBrowser/#/R-SPO-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Schizosaccharomyces pombe 30616 R-SPO-5678706 https://reactome.org/PathwayBrowser/#/R-SPO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Schizosaccharomyces pombe 30616 R-SPO-5679041 https://reactome.org/PathwayBrowser/#/R-SPO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Schizosaccharomyces pombe 30616 R-SPO-5679205 https://reactome.org/PathwayBrowser/#/R-SPO-5679205 ULK1 phosphorylates Beclin-1 IEA Schizosaccharomyces pombe 30616 R-SPO-5682026 https://reactome.org/PathwayBrowser/#/R-SPO-5682026 MRN bound to shortened telomeres activates ATM IEA Schizosaccharomyces pombe 30616 R-SPO-5682598 https://reactome.org/PathwayBrowser/#/R-SPO-5682598 ATM phosphorylates HERC2 IEA Schizosaccharomyces pombe 30616 R-SPO-5682983 https://reactome.org/PathwayBrowser/#/R-SPO-5682983 ATM phosphorylates WHSC1 IEA Schizosaccharomyces pombe 30616 R-SPO-5683425 https://reactome.org/PathwayBrowser/#/R-SPO-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Schizosaccharomyces pombe 30616 R-SPO-5683792 https://reactome.org/PathwayBrowser/#/R-SPO-5683792 p-T68-CHEK2 autophosphorylates IEA Schizosaccharomyces pombe 30616 R-SPO-5684096 https://reactome.org/PathwayBrowser/#/R-SPO-5684096 CDK2 phosphorylates RBBP8 IEA Schizosaccharomyces pombe 30616 R-SPO-5684140 https://reactome.org/PathwayBrowser/#/R-SPO-5684140 ATM phosphorylates RBBP8 IEA Schizosaccharomyces pombe 30616 R-SPO-5685230 https://reactome.org/PathwayBrowser/#/R-SPO-5685230 CHEK1 phosphorylates RAD51 IEA Schizosaccharomyces pombe 30616 R-SPO-5687086 https://reactome.org/PathwayBrowser/#/R-SPO-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Schizosaccharomyces pombe 30616 R-SPO-5690996 https://reactome.org/PathwayBrowser/#/R-SPO-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Schizosaccharomyces pombe 30616 R-SPO-5692462 https://reactome.org/PathwayBrowser/#/R-SPO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Schizosaccharomyces pombe 30616 R-SPO-5692480 https://reactome.org/PathwayBrowser/#/R-SPO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 30616 R-SPO-5693536 https://reactome.org/PathwayBrowser/#/R-SPO-5693536 ATM phosphorylates MDC1 IEA Schizosaccharomyces pombe 30616 R-SPO-5693540 https://reactome.org/PathwayBrowser/#/R-SPO-5693540 MRN activates ATM IEA Schizosaccharomyces pombe 30616 R-SPO-5693549 https://reactome.org/PathwayBrowser/#/R-SPO-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Schizosaccharomyces pombe 30616 R-SPO-5693598 https://reactome.org/PathwayBrowser/#/R-SPO-5693598 ATM phosphorylates NBN IEA Schizosaccharomyces pombe 30616 R-SPO-5694425 https://reactome.org/PathwayBrowser/#/R-SPO-5694425 NSF ATPase activity dissociates cis-SNARE IEA Schizosaccharomyces pombe 30616 R-SPO-5694441 https://reactome.org/PathwayBrowser/#/R-SPO-5694441 CSNK1D phosphorylates SEC23 IEA Schizosaccharomyces pombe 30616 R-SPO-5696074 https://reactome.org/PathwayBrowser/#/R-SPO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Schizosaccharomyces pombe 30616 R-SPO-5696839 https://reactome.org/PathwayBrowser/#/R-SPO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Schizosaccharomyces pombe 30616 R-SPO-6782131 https://reactome.org/PathwayBrowser/#/R-SPO-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Schizosaccharomyces pombe 30616 R-SPO-6788810 https://reactome.org/PathwayBrowser/#/R-SPO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Schizosaccharomyces pombe 30616 R-SPO-6795290 https://reactome.org/PathwayBrowser/#/R-SPO-6795290 TORC2 complex phosphorylates SGK1 IEA Schizosaccharomyces pombe 30616 R-SPO-6795473 https://reactome.org/PathwayBrowser/#/R-SPO-6795473 PDPK1 phosphorylates SGK1 IEA Schizosaccharomyces pombe 30616 R-SPO-6797606 https://reactome.org/PathwayBrowser/#/R-SPO-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Schizosaccharomyces pombe 30616 R-SPO-6798174 https://reactome.org/PathwayBrowser/#/R-SPO-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Schizosaccharomyces pombe 30616 R-SPO-6798372 https://reactome.org/PathwayBrowser/#/R-SPO-6798372 ATM phosphorylates DYRK2 IEA Schizosaccharomyces pombe 30616 R-SPO-6801342 https://reactome.org/PathwayBrowser/#/R-SPO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Schizosaccharomyces pombe 30616 R-SPO-6801456 https://reactome.org/PathwayBrowser/#/R-SPO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Schizosaccharomyces pombe 30616 R-SPO-6802973 https://reactome.org/PathwayBrowser/#/R-SPO-6802973 PLK3 phosphorylates CDC25C IEA Schizosaccharomyces pombe 30616 R-SPO-6805640 https://reactome.org/PathwayBrowser/#/R-SPO-6805640 AKT phosphorylates KAT6A IEA Schizosaccharomyces pombe 30616 R-SPO-6806877 https://reactome.org/PathwayBrowser/#/R-SPO-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Schizosaccharomyces pombe 30616 R-SPO-6806967 https://reactome.org/PathwayBrowser/#/R-SPO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Schizosaccharomyces pombe 30616 R-SPO-6807868 https://reactome.org/PathwayBrowser/#/R-SPO-6807868 GBF1 stimulates ARF nucleotide exchange IEA Schizosaccharomyces pombe 30616 R-SPO-6809015 https://reactome.org/PathwayBrowser/#/R-SPO-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Schizosaccharomyces pombe 30616 R-SPO-6810233 https://reactome.org/PathwayBrowser/#/R-SPO-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Schizosaccharomyces pombe 30616 R-SPO-6811422 https://reactome.org/PathwayBrowser/#/R-SPO-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Schizosaccharomyces pombe 30616 R-SPO-6811522 https://reactome.org/PathwayBrowser/#/R-SPO-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Schizosaccharomyces pombe 30616 R-SPO-6814120 https://reactome.org/PathwayBrowser/#/R-SPO-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Schizosaccharomyces pombe 30616 R-SPO-6814124 https://reactome.org/PathwayBrowser/#/R-SPO-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Schizosaccharomyces pombe 30616 R-SPO-68610 https://reactome.org/PathwayBrowser/#/R-SPO-68610 Formation of ORC(2-5) complex IEA Schizosaccharomyces pombe 30616 R-SPO-68944 https://reactome.org/PathwayBrowser/#/R-SPO-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Schizosaccharomyces pombe 30616 R-SPO-68954 https://reactome.org/PathwayBrowser/#/R-SPO-68954 Mcm2-7 is phosphorylated by DDK IEA Schizosaccharomyces pombe 30616 R-SPO-69005 https://reactome.org/PathwayBrowser/#/R-SPO-69005 Cdc6 protein is phosphorylated by CDK IEA Schizosaccharomyces pombe 30616 R-SPO-69063 https://reactome.org/PathwayBrowser/#/R-SPO-69063 Loading of PCNA - Sliding Clamp Formation IEA Schizosaccharomyces pombe 30616 R-SPO-69604 https://reactome.org/PathwayBrowser/#/R-SPO-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Schizosaccharomyces pombe 30616 R-SPO-69608 https://reactome.org/PathwayBrowser/#/R-SPO-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Schizosaccharomyces pombe 30616 R-SPO-70349 https://reactome.org/PathwayBrowser/#/R-SPO-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Schizosaccharomyces pombe 30616 R-SPO-70420 https://reactome.org/PathwayBrowser/#/R-SPO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Schizosaccharomyces pombe 30616 R-SPO-70467 https://reactome.org/PathwayBrowser/#/R-SPO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 30616 R-SPO-70486 https://reactome.org/PathwayBrowser/#/R-SPO-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Schizosaccharomyces pombe 30616 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 30616 R-SPO-70555 https://reactome.org/PathwayBrowser/#/R-SPO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Schizosaccharomyces pombe 30616 R-SPO-70599 https://reactome.org/PathwayBrowser/#/R-SPO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Schizosaccharomyces pombe 30616 R-SPO-70606 https://reactome.org/PathwayBrowser/#/R-SPO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Schizosaccharomyces pombe 30616 R-SPO-70967 https://reactome.org/PathwayBrowser/#/R-SPO-70967 IDH3 complex decarboxylates isocitrate IEA Schizosaccharomyces pombe 30616 R-SPO-70997 https://reactome.org/PathwayBrowser/#/R-SPO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Schizosaccharomyces pombe 30616 R-SPO-71401 https://reactome.org/PathwayBrowser/#/R-SPO-71401 OGDH dimer decarboxylates 2-OG IEA Schizosaccharomyces pombe 30616 R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 30616 R-SPO-71735 https://reactome.org/PathwayBrowser/#/R-SPO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Schizosaccharomyces pombe 30616 R-SPO-71802 https://reactome.org/PathwayBrowser/#/R-SPO-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 30616 R-SPO-71850 https://reactome.org/PathwayBrowser/#/R-SPO-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Schizosaccharomyces pombe 30616 R-SPO-72621 https://reactome.org/PathwayBrowser/#/R-SPO-72621 Ribosomal scanning IEA Schizosaccharomyces pombe 30616 R-SPO-72647 https://reactome.org/PathwayBrowser/#/R-SPO-72647 Cap-bound mRNA is activated by helicases IEA Schizosaccharomyces pombe 30616 R-SPO-73548 https://reactome.org/PathwayBrowser/#/R-SPO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Schizosaccharomyces pombe 30616 R-SPO-73577 https://reactome.org/PathwayBrowser/#/R-SPO-73577 CAD hexamer transforms L-Gln to CAP IEA Schizosaccharomyces pombe 30616 R-SPO-73580 https://reactome.org/PathwayBrowser/#/R-SPO-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Schizosaccharomyces pombe 30616 R-SPO-73635 https://reactome.org/PathwayBrowser/#/R-SPO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Schizosaccharomyces pombe 30616 R-SPO-73647 https://reactome.org/PathwayBrowser/#/R-SPO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Schizosaccharomyces pombe 30616 R-SPO-73788 https://reactome.org/PathwayBrowser/#/R-SPO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Schizosaccharomyces pombe 30616 R-SPO-73792 https://reactome.org/PathwayBrowser/#/R-SPO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Schizosaccharomyces pombe 30616 R-SPO-73810 https://reactome.org/PathwayBrowser/#/R-SPO-73810 FGAM + ATP => AIR + ADP + Pi IEA Schizosaccharomyces pombe 30616 R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 30616 R-SPO-73814 https://reactome.org/PathwayBrowser/#/R-SPO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Schizosaccharomyces pombe 30616 R-SPO-75010 https://reactome.org/PathwayBrowser/#/R-SPO-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Schizosaccharomyces pombe 30616 R-SPO-75040 https://reactome.org/PathwayBrowser/#/R-SPO-75040 Phosphorylation of Wee1 kinase by Chk1 TAS Schizosaccharomyces pombe 30616 R-SPO-75125 https://reactome.org/PathwayBrowser/#/R-SPO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Schizosaccharomyces pombe 30616 R-SPO-75126 https://reactome.org/PathwayBrowser/#/R-SPO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Schizosaccharomyces pombe 30616 R-SPO-75809 https://reactome.org/PathwayBrowser/#/R-SPO-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Schizosaccharomyces pombe 30616 R-SPO-75848 https://reactome.org/PathwayBrowser/#/R-SPO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Schizosaccharomyces pombe 30616 R-SPO-75851 https://reactome.org/PathwayBrowser/#/R-SPO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 30616 R-SPO-75949 https://reactome.org/PathwayBrowser/#/R-SPO-75949 RNA Polymerase II Promoter Opening: First Transition IEA Schizosaccharomyces pombe 30616 R-SPO-77071 https://reactome.org/PathwayBrowser/#/R-SPO-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Schizosaccharomyces pombe 30616 R-SPO-8847638 https://reactome.org/PathwayBrowser/#/R-SPO-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Schizosaccharomyces pombe 30616 R-SPO-8850945 https://reactome.org/PathwayBrowser/#/R-SPO-8850945 Casein kinase II phosphorylates PTEN IEA Schizosaccharomyces pombe 30616 R-SPO-8852128 https://reactome.org/PathwayBrowser/#/R-SPO-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Schizosaccharomyces pombe 30616 R-SPO-8852131 https://reactome.org/PathwayBrowser/#/R-SPO-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Schizosaccharomyces pombe 30616 R-SPO-8852132 https://reactome.org/PathwayBrowser/#/R-SPO-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-8852134 https://reactome.org/PathwayBrowser/#/R-SPO-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-8856813 https://reactome.org/PathwayBrowser/#/R-SPO-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Schizosaccharomyces pombe 30616 R-SPO-8868066 https://reactome.org/PathwayBrowser/#/R-SPO-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Schizosaccharomyces pombe 30616 R-SPO-8868660 https://reactome.org/PathwayBrowser/#/R-SPO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Schizosaccharomyces pombe 30616 R-SPO-8876446 https://reactome.org/PathwayBrowser/#/R-SPO-8876446 p-ULK1 phosphorylates DENND3 IEA Schizosaccharomyces pombe 30616 R-SPO-8876889 https://reactome.org/PathwayBrowser/#/R-SPO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 30616 R-SPO-8939959 https://reactome.org/PathwayBrowser/#/R-SPO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Schizosaccharomyces pombe 30616 R-SPO-8942836 https://reactome.org/PathwayBrowser/#/R-SPO-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Schizosaccharomyces pombe 30616 R-SPO-8948039 https://reactome.org/PathwayBrowser/#/R-SPO-8948039 FUNDC1 is phosphorylated by CK2 IEA Schizosaccharomyces pombe 30616 R-SPO-8948146 https://reactome.org/PathwayBrowser/#/R-SPO-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Schizosaccharomyces pombe 30616 R-SPO-8948757 https://reactome.org/PathwayBrowser/#/R-SPO-8948757 AKT phosphorylates MKRN1 IEA Schizosaccharomyces pombe 30616 R-SPO-8951648 https://reactome.org/PathwayBrowser/#/R-SPO-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Schizosaccharomyces pombe 30616 R-SPO-8951656 https://reactome.org/PathwayBrowser/#/R-SPO-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Schizosaccharomyces pombe 30616 R-SPO-8954327 https://reactome.org/PathwayBrowser/#/R-SPO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Schizosaccharomyces pombe 30616 R-SPO-8955844 https://reactome.org/PathwayBrowser/#/R-SPO-8955844 RBKS phosphorylates ribose to R5P IEA Schizosaccharomyces pombe 30616 R-SPO-9008043 https://reactome.org/PathwayBrowser/#/R-SPO-9008043 MAPK8 phosphorylation IEA Schizosaccharomyces pombe 30616 R-SPO-9012319 https://reactome.org/PathwayBrowser/#/R-SPO-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Schizosaccharomyces pombe 30616 R-SPO-9014741 https://reactome.org/PathwayBrowser/#/R-SPO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Schizosaccharomyces pombe 30616 R-SPO-9014766 https://reactome.org/PathwayBrowser/#/R-SPO-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Schizosaccharomyces pombe 30616 R-SPO-917693 https://reactome.org/PathwayBrowser/#/R-SPO-917693 ESCRT Disassembly IEA Schizosaccharomyces pombe 30616 R-SPO-917841 https://reactome.org/PathwayBrowser/#/R-SPO-917841 Acidification of Tf:TfR1 containing endosome IEA Schizosaccharomyces pombe 30616 R-SPO-927889 https://reactome.org/PathwayBrowser/#/R-SPO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Schizosaccharomyces pombe 30616 R-SPO-936883 https://reactome.org/PathwayBrowser/#/R-SPO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Schizosaccharomyces pombe 30616 R-SPO-936895 https://reactome.org/PathwayBrowser/#/R-SPO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Schizosaccharomyces pombe 30616 R-SPO-939763 https://reactome.org/PathwayBrowser/#/R-SPO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Schizosaccharomyces pombe 30616 R-SPO-947591 https://reactome.org/PathwayBrowser/#/R-SPO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Schizosaccharomyces pombe 30616 R-SPO-9606884 https://reactome.org/PathwayBrowser/#/R-SPO-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Schizosaccharomyces pombe 30616 R-SPO-9612509 https://reactome.org/PathwayBrowser/#/R-SPO-9612509 SGK phosphorylates SRF IEA Schizosaccharomyces pombe 30616 R-SPO-9613494 https://reactome.org/PathwayBrowser/#/R-SPO-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Schizosaccharomyces pombe 30616 R-SPO-9619355 https://reactome.org/PathwayBrowser/#/R-SPO-9619355 CaMKK autophosphorylates in the cytosol IEA Schizosaccharomyces pombe 30616 R-SPO-9626817 https://reactome.org/PathwayBrowser/#/R-SPO-9626817 PKC phosphorylates NCF1 IEA Schizosaccharomyces pombe 30616 R-SPO-9626832 https://reactome.org/PathwayBrowser/#/R-SPO-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Schizosaccharomyces pombe 30616 R-SPO-9626880 https://reactome.org/PathwayBrowser/#/R-SPO-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Schizosaccharomyces pombe 30616 R-SPO-9632858 https://reactome.org/PathwayBrowser/#/R-SPO-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Schizosaccharomyces pombe 30616 R-SPO-964958 https://reactome.org/PathwayBrowser/#/R-SPO-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Schizosaccharomyces pombe 30616 R-SPO-964962 https://reactome.org/PathwayBrowser/#/R-SPO-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Schizosaccharomyces pombe 30616 R-SPO-964970 https://reactome.org/PathwayBrowser/#/R-SPO-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Schizosaccharomyces pombe 30616 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 30616 R-SPO-9684118 https://reactome.org/PathwayBrowser/#/R-SPO-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Schizosaccharomyces pombe 30616 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 30616 R-SPO-9734687 https://reactome.org/PathwayBrowser/#/R-SPO-9734687 ORC6 is phosphorylated on T195 IEA Schizosaccharomyces pombe 30616 R-SPO-9748949 https://reactome.org/PathwayBrowser/#/R-SPO-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Schizosaccharomyces pombe 30616 R-SPO-9748957 https://reactome.org/PathwayBrowser/#/R-SPO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Schizosaccharomyces pombe 30616 R-SPO-9748963 https://reactome.org/PathwayBrowser/#/R-SPO-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Schizosaccharomyces pombe 30616 R-SPO-9748969 https://reactome.org/PathwayBrowser/#/R-SPO-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Schizosaccharomyces pombe 30616 R-SPO-9748999 https://reactome.org/PathwayBrowser/#/R-SPO-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Schizosaccharomyces pombe 30616 R-SPO-9750656 https://reactome.org/PathwayBrowser/#/R-SPO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Schizosaccharomyces pombe 30616 R-SPO-9753278 https://reactome.org/PathwayBrowser/#/R-SPO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 30616 R-SPO-9753283 https://reactome.org/PathwayBrowser/#/R-SPO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 30616 R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 30616 R-SPO-9754974 https://reactome.org/PathwayBrowser/#/R-SPO-9754974 ADK phosphorylates RBV IEA Schizosaccharomyces pombe 30616 R-SPO-9755013 https://reactome.org/PathwayBrowser/#/R-SPO-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Schizosaccharomyces pombe 30616 R-SPO-9759454 https://reactome.org/PathwayBrowser/#/R-SPO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Schizosaccharomyces pombe 30616 R-SPO-9759461 https://reactome.org/PathwayBrowser/#/R-SPO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Schizosaccharomyces pombe 30616 R-SPO-9760094 https://reactome.org/PathwayBrowser/#/R-SPO-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Schizosaccharomyces pombe 30616 R-SPO-983140 https://reactome.org/PathwayBrowser/#/R-SPO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Schizosaccharomyces pombe 30616 R-SPO-983144 https://reactome.org/PathwayBrowser/#/R-SPO-983144 Transport of Antigen peptide in to ER IEA Schizosaccharomyces pombe 30616 R-SPO-983153 https://reactome.org/PathwayBrowser/#/R-SPO-983153 E1 mediated ubiquitin activation IEA Schizosaccharomyces pombe 30616 R-SPO-983156 https://reactome.org/PathwayBrowser/#/R-SPO-983156 Polyubiquitination of substrate IEA Schizosaccharomyces pombe 30616 R-SPO-9837337 https://reactome.org/PathwayBrowser/#/R-SPO-9837337 DCAKD phosphorylates DP-CoA IEA Schizosaccharomyces pombe 30616 R-SPO-9838004 https://reactome.org/PathwayBrowser/#/R-SPO-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 30616 R-SPO-9838081 https://reactome.org/PathwayBrowser/#/R-SPO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Schizosaccharomyces pombe 30616 R-SPO-9838321 https://reactome.org/PathwayBrowser/#/R-SPO-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Schizosaccharomyces pombe 30616 R-SPO-9839105 https://reactome.org/PathwayBrowser/#/R-SPO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Schizosaccharomyces pombe 30616 R-SPO-9839113 https://reactome.org/PathwayBrowser/#/R-SPO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 30616 R-SPO-9840564 https://reactome.org/PathwayBrowser/#/R-SPO-9840564 OMA1 hydrolyzes YME1L1 IEA Schizosaccharomyces pombe 30616 R-SPO-9843721 https://reactome.org/PathwayBrowser/#/R-SPO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Schizosaccharomyces pombe 30616 R-SSC-109624 https://reactome.org/PathwayBrowser/#/R-SSC-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Sus scrofa 30616 R-SSC-109699 https://reactome.org/PathwayBrowser/#/R-SSC-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-109702 https://reactome.org/PathwayBrowser/#/R-SSC-109702 PDPK1 phosphorylates AKT2 IEA Sus scrofa 30616 R-SSC-109759 https://reactome.org/PathwayBrowser/#/R-SSC-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Sus scrofa 30616 R-SSC-109822 https://reactome.org/PathwayBrowser/#/R-SSC-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Sus scrofa 30616 R-SSC-109823 https://reactome.org/PathwayBrowser/#/R-SSC-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Sus scrofa 30616 R-SSC-109862 https://reactome.org/PathwayBrowser/#/R-SSC-109862 MAP2K2 phosphorylates MAPK1 IEA Sus scrofa 30616 R-SSC-109903 https://reactome.org/PathwayBrowser/#/R-SSC-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Sus scrofa 30616 R-SSC-110133 https://reactome.org/PathwayBrowser/#/R-SSC-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Sus scrofa 30616 R-SSC-110137 https://reactome.org/PathwayBrowser/#/R-SSC-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Sus scrofa 30616 R-SSC-110138 https://reactome.org/PathwayBrowser/#/R-SSC-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 30616 R-SSC-110141 https://reactome.org/PathwayBrowser/#/R-SSC-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Sus scrofa 30616 R-SSC-110144 https://reactome.org/PathwayBrowser/#/R-SSC-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Sus scrofa 30616 R-SSC-110145 https://reactome.org/PathwayBrowser/#/R-SSC-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Sus scrofa 30616 R-SSC-1112510 https://reactome.org/PathwayBrowser/#/R-SSC-1112510 IL6ST is tyrosine phosphorylated IEA Sus scrofa 30616 R-SSC-1112514 https://reactome.org/PathwayBrowser/#/R-SSC-1112514 JAK activation IEA Sus scrofa 30616 R-SSC-1112602 https://reactome.org/PathwayBrowser/#/R-SSC-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Sus scrofa 30616 R-SSC-1112703 https://reactome.org/PathwayBrowser/#/R-SSC-1112703 PTPN11 is phosphorylated IEA Sus scrofa 30616 R-SSC-1112727 https://reactome.org/PathwayBrowser/#/R-SSC-1112727 Serine phosphorylation of STATs IEA Sus scrofa 30616 R-SSC-111742 https://reactome.org/PathwayBrowser/#/R-SSC-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 30616 R-SSC-111751 https://reactome.org/PathwayBrowser/#/R-SSC-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 30616 R-SSC-111804 https://reactome.org/PathwayBrowser/#/R-SSC-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 30616 R-SSC-111898 https://reactome.org/PathwayBrowser/#/R-SSC-111898 Phosphorylation of cPLA2 by ERK-2 IEA Sus scrofa 30616 R-SSC-111930 https://reactome.org/PathwayBrowser/#/R-SSC-111930 Adenylate cyclase produces cAMP IEA Sus scrofa 30616 R-SSC-111970 https://reactome.org/PathwayBrowser/#/R-SSC-111970 PKC phosphorylates GRK2 IEA Sus scrofa 30616 R-SSC-112381 https://reactome.org/PathwayBrowser/#/R-SSC-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Sus scrofa 30616 R-SSC-114252 https://reactome.org/PathwayBrowser/#/R-SSC-114252 Cleavage of Procaspase-3 by the apoptosome IEA Sus scrofa 30616 R-SSC-114254 https://reactome.org/PathwayBrowser/#/R-SSC-114254 CYCS binds to APAF1 IEA Sus scrofa 30616 R-SSC-114256 https://reactome.org/PathwayBrowser/#/R-SSC-114256 CYCS:APAF1 binds procaspase-9 IEA Sus scrofa 30616 R-SSC-114261 https://reactome.org/PathwayBrowser/#/R-SSC-114261 Cleavage of Procaspase-7 by the apoptosome IEA Sus scrofa 30616 R-SSC-114600 https://reactome.org/PathwayBrowser/#/R-SSC-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Sus scrofa 30616 R-SSC-114683 https://reactome.org/PathwayBrowser/#/R-SSC-114683 Phosphorylation of Platelet Sec-1 IEA Sus scrofa 30616 R-SSC-114684 https://reactome.org/PathwayBrowser/#/R-SSC-114684 Phosphorylation of Syntaxin-4 IEA Sus scrofa 30616 R-SSC-1168459 https://reactome.org/PathwayBrowser/#/R-SSC-1168459 Lyn activates ERK IEA Sus scrofa 30616 R-SSC-1168638 https://reactome.org/PathwayBrowser/#/R-SSC-1168638 Activated IKK phosphorylates I-kappaB IEA Sus scrofa 30616 R-SSC-1169394 https://reactome.org/PathwayBrowser/#/R-SSC-1169394 ISGylation of IRF3 IEA Sus scrofa 30616 R-SSC-1169397 https://reactome.org/PathwayBrowser/#/R-SSC-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Sus scrofa 30616 R-SSC-1169398 https://reactome.org/PathwayBrowser/#/R-SSC-1169398 ISGylation of host protein filamin B IEA Sus scrofa 30616 R-SSC-1169402 https://reactome.org/PathwayBrowser/#/R-SSC-1169402 ISGylation of E2 conjugating enzymes IEA Sus scrofa 30616 R-SSC-1169405 https://reactome.org/PathwayBrowser/#/R-SSC-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Sus scrofa 30616 R-SSC-1169406 https://reactome.org/PathwayBrowser/#/R-SSC-1169406 ISGylation of host proteins IEA Sus scrofa 30616 R-SSC-1181149 https://reactome.org/PathwayBrowser/#/R-SSC-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Sus scrofa 30616 R-SSC-1226094 https://reactome.org/PathwayBrowser/#/R-SSC-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Sus scrofa 30616 R-SSC-1226095 https://reactome.org/PathwayBrowser/#/R-SSC-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Sus scrofa 30616 R-SSC-1247935 https://reactome.org/PathwayBrowser/#/R-SSC-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Sus scrofa 30616 R-SSC-1247960 https://reactome.org/PathwayBrowser/#/R-SSC-1247960 Activation of p38 MAPK IEA Sus scrofa 30616 R-SSC-1250195 https://reactome.org/PathwayBrowser/#/R-SSC-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Sus scrofa 30616 R-SSC-1250315 https://reactome.org/PathwayBrowser/#/R-SSC-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Sus scrofa 30616 R-SSC-1250348 https://reactome.org/PathwayBrowser/#/R-SSC-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Sus scrofa 30616 R-SSC-1250370 https://reactome.org/PathwayBrowser/#/R-SSC-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Sus scrofa 30616 R-SSC-1250462 https://reactome.org/PathwayBrowser/#/R-SSC-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Sus scrofa 30616 R-SSC-1295540 https://reactome.org/PathwayBrowser/#/R-SSC-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Sus scrofa 30616 R-SSC-1295609 https://reactome.org/PathwayBrowser/#/R-SSC-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Sus scrofa 30616 R-SSC-1296024 https://reactome.org/PathwayBrowser/#/R-SSC-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Sus scrofa 30616 R-SSC-1306957 https://reactome.org/PathwayBrowser/#/R-SSC-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Sus scrofa 30616 R-SSC-1306979 https://reactome.org/PathwayBrowser/#/R-SSC-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Sus scrofa 30616 R-SSC-1307963 https://reactome.org/PathwayBrowser/#/R-SSC-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Sus scrofa 30616 R-SSC-1362270 https://reactome.org/PathwayBrowser/#/R-SSC-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Sus scrofa 30616 R-SSC-1369028 https://reactome.org/PathwayBrowser/#/R-SSC-1369028 ABCAs mediate lipid efflux IEA Sus scrofa 30616 R-SSC-1369052 https://reactome.org/PathwayBrowser/#/R-SSC-1369052 ABCAs mediate lipid influx IEA Sus scrofa 30616 R-SSC-1369065 https://reactome.org/PathwayBrowser/#/R-SSC-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Sus scrofa 30616 R-SSC-1370505 https://reactome.org/PathwayBrowser/#/R-SSC-1370505 PRLR is phosphorylated at Ser-349 IEA Sus scrofa 30616 R-SSC-139855 https://reactome.org/PathwayBrowser/#/R-SSC-139855 P2X1-mediated entry of Ca++ from plasma IEA Sus scrofa 30616 R-SSC-139908 https://reactome.org/PathwayBrowser/#/R-SSC-139908 Phosphorylation of DLC2 by MAPK8 IEA Sus scrofa 30616 R-SSC-139918 https://reactome.org/PathwayBrowser/#/R-SSC-139918 Phosphorylation of BIM by JNK IEA Sus scrofa 30616 R-SSC-1433418 https://reactome.org/PathwayBrowser/#/R-SSC-1433418 Phosphorylation of JAK2 IEA Sus scrofa 30616 R-SSC-1433454 https://reactome.org/PathwayBrowser/#/R-SSC-1433454 Phosphorylation of GAB2 by SFKs IEA Sus scrofa 30616 R-SSC-1433488 https://reactome.org/PathwayBrowser/#/R-SSC-1433488 Phosphorylation of SHP2 by SFKs IEA Sus scrofa 30616 R-SSC-1433506 https://reactome.org/PathwayBrowser/#/R-SSC-1433506 Phosphorylation of APS IEA Sus scrofa 30616 R-SSC-1433508 https://reactome.org/PathwayBrowser/#/R-SSC-1433508 PKC alpha interacts with and phosphorylates KIT IEA Sus scrofa 30616 R-SSC-1433514 https://reactome.org/PathwayBrowser/#/R-SSC-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Sus scrofa 30616 R-SSC-1433542 https://reactome.org/PathwayBrowser/#/R-SSC-1433542 Phosphorylation and activation of VAV1 IEA Sus scrofa 30616 R-SSC-1454916 https://reactome.org/PathwayBrowser/#/R-SSC-1454916 The ABCC family mediates organic anion transport IEA Sus scrofa 30616 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-1467466 https://reactome.org/PathwayBrowser/#/R-SSC-1467466 ABCA4 mediates atRAL transport IEA Sus scrofa 30616 R-SSC-1470009 https://reactome.org/PathwayBrowser/#/R-SSC-1470009 Phosphorylation of STATs IEA Sus scrofa 30616 R-SSC-1472121 https://reactome.org/PathwayBrowser/#/R-SSC-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Sus scrofa 30616 R-SSC-1475422 https://reactome.org/PathwayBrowser/#/R-SSC-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Sus scrofa 30616 R-SSC-1483004 https://reactome.org/PathwayBrowser/#/R-SSC-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Sus scrofa 30616 R-SSC-1483222 https://reactome.org/PathwayBrowser/#/R-SSC-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Sus scrofa 30616 R-SSC-1497853 https://reactome.org/PathwayBrowser/#/R-SSC-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Sus scrofa 30616 R-SSC-1524186 https://reactome.org/PathwayBrowser/#/R-SSC-1524186 Phosphorylation of PLCgamma by PDGFR IEA Sus scrofa 30616 R-SSC-1549526 https://reactome.org/PathwayBrowser/#/R-SSC-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Sus scrofa 30616 R-SSC-156673 https://reactome.org/PathwayBrowser/#/R-SSC-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Sus scrofa 30616 R-SSC-156678 https://reactome.org/PathwayBrowser/#/R-SSC-156678 Activation of Cdc25C IEA Sus scrofa 30616 R-SSC-156682 https://reactome.org/PathwayBrowser/#/R-SSC-156682 PLK1 phosphorylates NUDC IEA Sus scrofa 30616 R-SSC-156699 https://reactome.org/PathwayBrowser/#/R-SSC-156699 Inactivation of Wee1 kinase IEA Sus scrofa 30616 R-SSC-156723 https://reactome.org/PathwayBrowser/#/R-SSC-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Sus scrofa 30616 R-SSC-159101 https://reactome.org/PathwayBrowser/#/R-SSC-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Sus scrofa 30616 R-SSC-159425 https://reactome.org/PathwayBrowser/#/R-SSC-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 30616 R-SSC-159443 https://reactome.org/PathwayBrowser/#/R-SSC-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 30616 R-SSC-159567 https://reactome.org/PathwayBrowser/#/R-SSC-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Sus scrofa 30616 R-SSC-162657 https://reactome.org/PathwayBrowser/#/R-SSC-162657 Inactivation of Myt1 kinase IEA Sus scrofa 30616 R-SSC-163010 https://reactome.org/PathwayBrowser/#/R-SSC-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Sus scrofa 30616 R-SSC-163120 https://reactome.org/PathwayBrowser/#/R-SSC-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Sus scrofa 30616 R-SSC-163215 https://reactome.org/PathwayBrowser/#/R-SSC-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Sus scrofa 30616 R-SSC-1632857 https://reactome.org/PathwayBrowser/#/R-SSC-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Sus scrofa 30616 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa 30616 R-SSC-1638845 https://reactome.org/PathwayBrowser/#/R-SSC-1638845 CERK phosphorylates CERA to form C1P IEA Sus scrofa 30616 R-SSC-164832 https://reactome.org/PathwayBrowser/#/R-SSC-164832 ATPase synthesizes ATP IEA Sus scrofa 30616 R-SSC-164834 https://reactome.org/PathwayBrowser/#/R-SSC-164834 Enzyme-bound ATP is released IEA Sus scrofa 30616 R-SSC-165162 https://reactome.org/PathwayBrowser/#/R-SSC-165162 Phosphorylation of TSC2 by PKB IEA Sus scrofa 30616 R-SSC-165182 https://reactome.org/PathwayBrowser/#/R-SSC-165182 Phosphorylation of complexed TSC2 by PKB IEA Sus scrofa 30616 R-SSC-165692 https://reactome.org/PathwayBrowser/#/R-SSC-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Sus scrofa 30616 R-SSC-165718 https://reactome.org/PathwayBrowser/#/R-SSC-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Sus scrofa 30616 R-SSC-165726 https://reactome.org/PathwayBrowser/#/R-SSC-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Sus scrofa 30616 R-SSC-165758 https://reactome.org/PathwayBrowser/#/R-SSC-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Sus scrofa 30616 R-SSC-165766 https://reactome.org/PathwayBrowser/#/R-SSC-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Sus scrofa 30616 R-SSC-165777 https://reactome.org/PathwayBrowser/#/R-SSC-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Sus scrofa 30616 R-SSC-166245 https://reactome.org/PathwayBrowser/#/R-SSC-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Sus scrofa 30616 R-SSC-1675773 https://reactome.org/PathwayBrowser/#/R-SSC-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Sus scrofa 30616 R-SSC-1675776 https://reactome.org/PathwayBrowser/#/R-SSC-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Sus scrofa 30616 R-SSC-1675780 https://reactome.org/PathwayBrowser/#/R-SSC-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Sus scrofa 30616 R-SSC-1675810 https://reactome.org/PathwayBrowser/#/R-SSC-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Sus scrofa 30616 R-SSC-1675813 https://reactome.org/PathwayBrowser/#/R-SSC-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Sus scrofa 30616 R-SSC-1675883 https://reactome.org/PathwayBrowser/#/R-SSC-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Sus scrofa 30616 R-SSC-1675928 https://reactome.org/PathwayBrowser/#/R-SSC-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Sus scrofa 30616 R-SSC-1675939 https://reactome.org/PathwayBrowser/#/R-SSC-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Sus scrofa 30616 R-SSC-1675961 https://reactome.org/PathwayBrowser/#/R-SSC-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Sus scrofa 30616 R-SSC-1675974 https://reactome.org/PathwayBrowser/#/R-SSC-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Sus scrofa 30616 R-SSC-1676024 https://reactome.org/PathwayBrowser/#/R-SSC-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Sus scrofa 30616 R-SSC-1676048 https://reactome.org/PathwayBrowser/#/R-SSC-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Sus scrofa 30616 R-SSC-1676082 https://reactome.org/PathwayBrowser/#/R-SSC-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Sus scrofa 30616 R-SSC-1676109 https://reactome.org/PathwayBrowser/#/R-SSC-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Sus scrofa 30616 R-SSC-1676134 https://reactome.org/PathwayBrowser/#/R-SSC-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Sus scrofa 30616 R-SSC-1676145 https://reactome.org/PathwayBrowser/#/R-SSC-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Sus scrofa 30616 R-SSC-1676185 https://reactome.org/PathwayBrowser/#/R-SSC-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Sus scrofa 30616 R-SSC-1676206 https://reactome.org/PathwayBrowser/#/R-SSC-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Sus scrofa 30616 R-SSC-1678923 https://reactome.org/PathwayBrowser/#/R-SSC-1678923 TLR folding by chaperones GP96 and CNPY3 IEA Sus scrofa 30616 R-SSC-1678944 https://reactome.org/PathwayBrowser/#/R-SSC-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Sus scrofa 30616 R-SSC-168053 https://reactome.org/PathwayBrowser/#/R-SSC-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Sus scrofa 30616 R-SSC-168136 https://reactome.org/PathwayBrowser/#/R-SSC-168136 Activated JNKs phosphorylate c-JUN IEA Sus scrofa 30616 R-SSC-168140 https://reactome.org/PathwayBrowser/#/R-SSC-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Sus scrofa 30616 R-SSC-168162 https://reactome.org/PathwayBrowser/#/R-SSC-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Sus scrofa 30616 R-SSC-169905 https://reactome.org/PathwayBrowser/#/R-SSC-169905 ARMS is phosphorylated by active TrkA receptor IEA Sus scrofa 30616 R-SSC-170026 https://reactome.org/PathwayBrowser/#/R-SSC-170026 Protons are translocated from the intermembrane space to the matrix IEA Sus scrofa 30616 R-SSC-170055 https://reactome.org/PathwayBrowser/#/R-SSC-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Sus scrofa 30616 R-SSC-170070 https://reactome.org/PathwayBrowser/#/R-SSC-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Sus scrofa 30616 R-SSC-170076 https://reactome.org/PathwayBrowser/#/R-SSC-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Sus scrofa 30616 R-SSC-170087 https://reactome.org/PathwayBrowser/#/R-SSC-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Sus scrofa 30616 R-SSC-170126 https://reactome.org/PathwayBrowser/#/R-SSC-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Sus scrofa 30616 R-SSC-170676 https://reactome.org/PathwayBrowser/#/R-SSC-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Sus scrofa 30616 R-SSC-170843 https://reactome.org/PathwayBrowser/#/R-SSC-170843 TGFBR2 phosphorylates TGFBR1 IEA Sus scrofa 30616 R-SSC-170868 https://reactome.org/PathwayBrowser/#/R-SSC-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Sus scrofa 30616 R-SSC-170977 https://reactome.org/PathwayBrowser/#/R-SSC-170977 FRS2 is phosphorylated by active TrkA receptor IEA Sus scrofa 30616 R-SSC-174079 https://reactome.org/PathwayBrowser/#/R-SSC-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa 30616 R-SSC-174122 https://reactome.org/PathwayBrowser/#/R-SSC-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Sus scrofa 30616 R-SSC-174164 https://reactome.org/PathwayBrowser/#/R-SSC-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Sus scrofa 30616 R-SSC-174174 https://reactome.org/PathwayBrowser/#/R-SSC-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Sus scrofa 30616 R-SSC-174251 https://reactome.org/PathwayBrowser/#/R-SSC-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Sus scrofa 30616 R-SSC-174367 https://reactome.org/PathwayBrowser/#/R-SSC-174367 GCL ligates L-Glu to L-Cys IEA Sus scrofa 30616 R-SSC-174389 https://reactome.org/PathwayBrowser/#/R-SSC-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Sus scrofa 30616 R-SSC-174391 https://reactome.org/PathwayBrowser/#/R-SSC-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Sus scrofa 30616 R-SSC-174392 https://reactome.org/PathwayBrowser/#/R-SSC-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Sus scrofa 30616 R-SSC-174394 https://reactome.org/PathwayBrowser/#/R-SSC-174394 GSS:Mg2+ dimer synthesizes GSH IEA Sus scrofa 30616 R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa 30616 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa 30616 R-SSC-176116 https://reactome.org/PathwayBrowser/#/R-SSC-176116 Recruitment and activation of Chk1 IEA Sus scrofa 30616 R-SSC-176298 https://reactome.org/PathwayBrowser/#/R-SSC-176298 Activation of claspin IEA Sus scrofa 30616 R-SSC-177157 https://reactome.org/PathwayBrowser/#/R-SSC-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Sus scrofa 30616 R-SSC-177275 https://reactome.org/PathwayBrowser/#/R-SSC-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Sus scrofa 30616 R-SSC-177284 https://reactome.org/PathwayBrowser/#/R-SSC-177284 PKA phosphorylates PDE4B IEA Sus scrofa 30616 R-SSC-177930 https://reactome.org/PathwayBrowser/#/R-SSC-177930 GAB1 phosphorylation by EGFR kinase IEA Sus scrofa 30616 R-SSC-177933 https://reactome.org/PathwayBrowser/#/R-SSC-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Sus scrofa 30616 R-SSC-177934 https://reactome.org/PathwayBrowser/#/R-SSC-177934 EGFR autophosphorylation IEA Sus scrofa 30616 R-SSC-177937 https://reactome.org/PathwayBrowser/#/R-SSC-177937 Phosphorylation of EGFR by SRC kinase IEA Sus scrofa 30616 R-SSC-177939 https://reactome.org/PathwayBrowser/#/R-SSC-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Sus scrofa 30616 R-SSC-182969 https://reactome.org/PathwayBrowser/#/R-SSC-182969 Phosphorylation of CBL (EGFR:CBL) IEA Sus scrofa 30616 R-SSC-183058 https://reactome.org/PathwayBrowser/#/R-SSC-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Sus scrofa 30616 R-SSC-1855153 https://reactome.org/PathwayBrowser/#/R-SSC-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Sus scrofa 30616 R-SSC-1855157 https://reactome.org/PathwayBrowser/#/R-SSC-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Sus scrofa 30616 R-SSC-1855158 https://reactome.org/PathwayBrowser/#/R-SSC-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Sus scrofa 30616 R-SSC-1855162 https://reactome.org/PathwayBrowser/#/R-SSC-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Sus scrofa 30616 R-SSC-1855169 https://reactome.org/PathwayBrowser/#/R-SSC-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 30616 R-SSC-1855172 https://reactome.org/PathwayBrowser/#/R-SSC-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Sus scrofa 30616 R-SSC-1855176 https://reactome.org/PathwayBrowser/#/R-SSC-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Sus scrofa 30616 R-SSC-1855179 https://reactome.org/PathwayBrowser/#/R-SSC-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Sus scrofa 30616 R-SSC-1855181 https://reactome.org/PathwayBrowser/#/R-SSC-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Sus scrofa 30616 R-SSC-1855182 https://reactome.org/PathwayBrowser/#/R-SSC-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Sus scrofa 30616 R-SSC-1855193 https://reactome.org/PathwayBrowser/#/R-SSC-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Sus scrofa 30616 R-SSC-1855194 https://reactome.org/PathwayBrowser/#/R-SSC-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Sus scrofa 30616 R-SSC-1855197 https://reactome.org/PathwayBrowser/#/R-SSC-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 30616 R-SSC-1855207 https://reactome.org/PathwayBrowser/#/R-SSC-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Sus scrofa 30616 R-SSC-1855216 https://reactome.org/PathwayBrowser/#/R-SSC-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Sus scrofa 30616 R-SSC-1855223 https://reactome.org/PathwayBrowser/#/R-SSC-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Sus scrofa 30616 R-SSC-1855224 https://reactome.org/PathwayBrowser/#/R-SSC-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Sus scrofa 30616 R-SSC-1855227 https://reactome.org/PathwayBrowser/#/R-SSC-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Sus scrofa 30616 R-SSC-1855230 https://reactome.org/PathwayBrowser/#/R-SSC-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Sus scrofa 30616 R-SSC-1861595 https://reactome.org/PathwayBrowser/#/R-SSC-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Sus scrofa 30616 R-SSC-186786 https://reactome.org/PathwayBrowser/#/R-SSC-186786 Autophosphorylation of PDGF beta receptors IEA Sus scrofa 30616 R-SSC-186800 https://reactome.org/PathwayBrowser/#/R-SSC-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-187520 https://reactome.org/PathwayBrowser/#/R-SSC-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Sus scrofa 30616 R-SSC-187688 https://reactome.org/PathwayBrowser/#/R-SSC-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Sus scrofa 30616 R-SSC-187916 https://reactome.org/PathwayBrowser/#/R-SSC-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Sus scrofa 30616 R-SSC-187948 https://reactome.org/PathwayBrowser/#/R-SSC-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Sus scrofa 30616 R-SSC-187949 https://reactome.org/PathwayBrowser/#/R-SSC-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Sus scrofa 30616 R-SSC-187959 https://reactome.org/PathwayBrowser/#/R-SSC-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Sus scrofa 30616 R-SSC-188350 https://reactome.org/PathwayBrowser/#/R-SSC-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Sus scrofa 30616 R-SSC-188390 https://reactome.org/PathwayBrowser/#/R-SSC-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Sus scrofa 30616 R-SSC-190326 https://reactome.org/PathwayBrowser/#/R-SSC-190326 Autocatalytic phosphorylation of FGFR4 IEA Sus scrofa 30616 R-SSC-190427 https://reactome.org/PathwayBrowser/#/R-SSC-190427 Autocatalytic phosphorylation of FGFR1b IEA Sus scrofa 30616 R-SSC-190429 https://reactome.org/PathwayBrowser/#/R-SSC-190429 Autocatalytic phosphorylation of FGFR1c IEA Sus scrofa 30616 R-SSC-191062 https://reactome.org/PathwayBrowser/#/R-SSC-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Sus scrofa 30616 R-SSC-191380 https://reactome.org/PathwayBrowser/#/R-SSC-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Sus scrofa 30616 R-SSC-191414 https://reactome.org/PathwayBrowser/#/R-SSC-191414 MVD decarboxylates MVA5PP to IPPP IEA Sus scrofa 30616 R-SSC-191422 https://reactome.org/PathwayBrowser/#/R-SSC-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Sus scrofa 30616 R-SSC-191636 https://reactome.org/PathwayBrowser/#/R-SSC-191636 Phosphorylation of Cx43 by c-src IEA Sus scrofa 30616 R-SSC-192137 https://reactome.org/PathwayBrowser/#/R-SSC-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 30616 R-SSC-193362 https://reactome.org/PathwayBrowser/#/R-SSC-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-193401 https://reactome.org/PathwayBrowser/#/R-SSC-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 30616 R-SSC-193407 https://reactome.org/PathwayBrowser/#/R-SSC-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 30616 R-SSC-193424 https://reactome.org/PathwayBrowser/#/R-SSC-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 30616 R-SSC-193703 https://reactome.org/PathwayBrowser/#/R-SSC-193703 IKKbeta is activated IEA Sus scrofa 30616 R-SSC-193705 https://reactome.org/PathwayBrowser/#/R-SSC-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Sus scrofa 30616 R-SSC-193711 https://reactome.org/PathwayBrowser/#/R-SSC-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 30616 R-SSC-193727 https://reactome.org/PathwayBrowser/#/R-SSC-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 30616 R-SSC-193743 https://reactome.org/PathwayBrowser/#/R-SSC-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 30616 R-SSC-193766 https://reactome.org/PathwayBrowser/#/R-SSC-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 30616 R-SSC-194153 https://reactome.org/PathwayBrowser/#/R-SSC-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-195275 https://reactome.org/PathwayBrowser/#/R-SSC-195275 Phosphorylation of APC component of the destruction complex IEA Sus scrofa 30616 R-SSC-195283 https://reactome.org/PathwayBrowser/#/R-SSC-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Sus scrofa 30616 R-SSC-195287 https://reactome.org/PathwayBrowser/#/R-SSC-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Sus scrofa 30616 R-SSC-195300 https://reactome.org/PathwayBrowser/#/R-SSC-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Sus scrofa 30616 R-SSC-195318 https://reactome.org/PathwayBrowser/#/R-SSC-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Sus scrofa 30616 R-SSC-1963581 https://reactome.org/PathwayBrowser/#/R-SSC-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Sus scrofa 30616 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 30616 R-SSC-1963586 https://reactome.org/PathwayBrowser/#/R-SSC-1963586 SRC family kinases phosphorylate ERBB2 IEA Sus scrofa 30616 R-SSC-196753 https://reactome.org/PathwayBrowser/#/R-SSC-196753 2xPPCS ligates PPanK with Cys IEA Sus scrofa 30616 R-SSC-196754 https://reactome.org/PathwayBrowser/#/R-SSC-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Sus scrofa 30616 R-SSC-196761 https://reactome.org/PathwayBrowser/#/R-SSC-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Sus scrofa 30616 R-SSC-196773 https://reactome.org/PathwayBrowser/#/R-SSC-196773 COASY phosphorylates DP-CoA IEA Sus scrofa 30616 R-SSC-196857 https://reactome.org/PathwayBrowser/#/R-SSC-196857 PANK2 phosphorylates PanK IEA Sus scrofa 30616 R-SSC-196929 https://reactome.org/PathwayBrowser/#/R-SSC-196929 FLAD1 phosphorylates FMN IEA Sus scrofa 30616 R-SSC-196964 https://reactome.org/PathwayBrowser/#/R-SSC-196964 RFK:Mg2+ phosphorylates RIB IEA Sus scrofa 30616 R-SSC-197198 https://reactome.org/PathwayBrowser/#/R-SSC-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Sus scrofa 30616 R-SSC-197235 https://reactome.org/PathwayBrowser/#/R-SSC-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 30616 R-SSC-197271 https://reactome.org/PathwayBrowser/#/R-SSC-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Sus scrofa 30616 R-SSC-197958 https://reactome.org/PathwayBrowser/#/R-SSC-197958 FPGS-2 transforms THF to THFPG IEA Sus scrofa 30616 R-SSC-198266 https://reactome.org/PathwayBrowser/#/R-SSC-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Sus scrofa 30616 R-SSC-198314 https://reactome.org/PathwayBrowser/#/R-SSC-198314 DAG stimulates protein kinase C-delta IEA Sus scrofa 30616 R-SSC-198669 https://reactome.org/PathwayBrowser/#/R-SSC-198669 p38MAPK phosphorylates MSK1 IEA Sus scrofa 30616 R-SSC-198746 https://reactome.org/PathwayBrowser/#/R-SSC-198746 ERK1/2/5 activate RSK1/2/3 IEA Sus scrofa 30616 R-SSC-198756 https://reactome.org/PathwayBrowser/#/R-SSC-198756 ERK1/2 phosphorylates MSK1 IEA Sus scrofa 30616 R-SSC-199203 https://reactome.org/PathwayBrowser/#/R-SSC-199203 PANK1/3 phosphorylate PanK IEA Sus scrofa 30616 R-SSC-199895 https://reactome.org/PathwayBrowser/#/R-SSC-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Sus scrofa 30616 R-SSC-199910 https://reactome.org/PathwayBrowser/#/R-SSC-199910 MSK1 activates ATF1 IEA Sus scrofa 30616 R-SSC-199917 https://reactome.org/PathwayBrowser/#/R-SSC-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Sus scrofa 30616 R-SSC-199935 https://reactome.org/PathwayBrowser/#/R-SSC-199935 MSK1 activates CREB IEA Sus scrofa 30616 R-SSC-200318 https://reactome.org/PathwayBrowser/#/R-SSC-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Sus scrofa 30616 R-SSC-200326 https://reactome.org/PathwayBrowser/#/R-SSC-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Sus scrofa 30616 R-SSC-200421 https://reactome.org/PathwayBrowser/#/R-SSC-200421 Activation of cytosolic AMPK by phosphorylation IEA Sus scrofa 30616 R-SSC-200423 https://reactome.org/PathwayBrowser/#/R-SSC-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Sus scrofa 30616 R-SSC-200474 https://reactome.org/PathwayBrowser/#/R-SSC-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 30616 R-SSC-200512 https://reactome.org/PathwayBrowser/#/R-SSC-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 30616 R-SSC-200555 https://reactome.org/PathwayBrowser/#/R-SSC-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Sus scrofa 30616 R-SSC-200681 https://reactome.org/PathwayBrowser/#/R-SSC-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Sus scrofa 30616 R-SSC-200682 https://reactome.org/PathwayBrowser/#/R-SSC-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Sus scrofa 30616 R-SSC-200711 https://reactome.org/PathwayBrowser/#/R-SSC-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Sus scrofa 30616 R-SSC-201035 https://reactome.org/PathwayBrowser/#/R-SSC-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Sus scrofa 30616 R-SSC-201443 https://reactome.org/PathwayBrowser/#/R-SSC-201443 Type II receptor phosphorylates type I receptor IEA Sus scrofa 30616 R-SSC-201476 https://reactome.org/PathwayBrowser/#/R-SSC-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Sus scrofa 30616 R-SSC-201510 https://reactome.org/PathwayBrowser/#/R-SSC-201510 PI3K synthesizes PIP3 downstream of ALK IEA Sus scrofa 30616 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 30616 R-SSC-201677 https://reactome.org/PathwayBrowser/#/R-SSC-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Sus scrofa 30616 R-SSC-201717 https://reactome.org/PathwayBrowser/#/R-SSC-201717 CSNK2-mediated phosphorylation of DVL IEA Sus scrofa 30616 R-SSC-202111 https://reactome.org/PathwayBrowser/#/R-SSC-202111 AKT1 phosphorylates eNOS IEA Sus scrofa 30616 R-SSC-202165 https://reactome.org/PathwayBrowser/#/R-SSC-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Sus scrofa 30616 R-SSC-202168 https://reactome.org/PathwayBrowser/#/R-SSC-202168 Phosphorylation of ZAP-70 by Lck IEA Sus scrofa 30616 R-SSC-202174 https://reactome.org/PathwayBrowser/#/R-SSC-202174 Activation of ZAP-70 IEA Sus scrofa 30616 R-SSC-202216 https://reactome.org/PathwayBrowser/#/R-SSC-202216 Phosphorylation of SLP-76 IEA Sus scrofa 30616 R-SSC-202222 https://reactome.org/PathwayBrowser/#/R-SSC-202222 Phosphorylation of PKC theta IEA Sus scrofa 30616 R-SSC-202233 https://reactome.org/PathwayBrowser/#/R-SSC-202233 Inactivation of Lck by Csk IEA Sus scrofa 30616 R-SSC-202245 https://reactome.org/PathwayBrowser/#/R-SSC-202245 Phosphorylation of TBSMs in LAT IEA Sus scrofa 30616 R-SSC-202248 https://reactome.org/PathwayBrowser/#/R-SSC-202248 Phosphorylation of PLC-gamma1 IEA Sus scrofa 30616 R-SSC-202291 https://reactome.org/PathwayBrowser/#/R-SSC-202291 Activation of Lck IEA Sus scrofa 30616 R-SSC-202307 https://reactome.org/PathwayBrowser/#/R-SSC-202307 Change of PKC theta conformation IEA Sus scrofa 30616 R-SSC-202365 https://reactome.org/PathwayBrowser/#/R-SSC-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-202437 https://reactome.org/PathwayBrowser/#/R-SSC-202437 Phosphorylation of CARMA1 IEA Sus scrofa 30616 R-SSC-202459 https://reactome.org/PathwayBrowser/#/R-SSC-202459 Phosphorylation of Bcl10 IEA Sus scrofa 30616 R-SSC-202500 https://reactome.org/PathwayBrowser/#/R-SSC-202500 Activation of IKK complex IEA Sus scrofa 30616 R-SSC-202510 https://reactome.org/PathwayBrowser/#/R-SSC-202510 Activation of TAK1-TAB2 complex IEA Sus scrofa 30616 R-SSC-202541 https://reactome.org/PathwayBrowser/#/R-SSC-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Sus scrofa 30616 R-SSC-2028284 https://reactome.org/PathwayBrowser/#/R-SSC-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Sus scrofa 30616 R-SSC-2028555 https://reactome.org/PathwayBrowser/#/R-SSC-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Sus scrofa 30616 R-SSC-2028583 https://reactome.org/PathwayBrowser/#/R-SSC-2028583 Phosphorylation of YAP by LATS2 IEA Sus scrofa 30616 R-SSC-2028589 https://reactome.org/PathwayBrowser/#/R-SSC-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Sus scrofa 30616 R-SSC-2028591 https://reactome.org/PathwayBrowser/#/R-SSC-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Sus scrofa 30616 R-SSC-2028598 https://reactome.org/PathwayBrowser/#/R-SSC-2028598 Phosphorylation of YAP by LATS1 IEA Sus scrofa 30616 R-SSC-2028629 https://reactome.org/PathwayBrowser/#/R-SSC-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Sus scrofa 30616 R-SSC-2028635 https://reactome.org/PathwayBrowser/#/R-SSC-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Sus scrofa 30616 R-SSC-2028661 https://reactome.org/PathwayBrowser/#/R-SSC-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Sus scrofa 30616 R-SSC-2028670 https://reactome.org/PathwayBrowser/#/R-SSC-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Sus scrofa 30616 R-SSC-2028673 https://reactome.org/PathwayBrowser/#/R-SSC-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Sus scrofa 30616 R-SSC-2028675 https://reactome.org/PathwayBrowser/#/R-SSC-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Sus scrofa 30616 R-SSC-2028679 https://reactome.org/PathwayBrowser/#/R-SSC-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Sus scrofa 30616 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa 30616 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa 30616 R-SSC-2029454 https://reactome.org/PathwayBrowser/#/R-SSC-2029454 Autophosphorylation of PAK1 IEA Sus scrofa 30616 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa 30616 R-SSC-2029460 https://reactome.org/PathwayBrowser/#/R-SSC-2029460 PAK1 phosphorylates LIMK1 IEA Sus scrofa 30616 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa 30616 R-SSC-2029469 https://reactome.org/PathwayBrowser/#/R-SSC-2029469 p-ERK phosphorylates WAVEs and ABI IEA Sus scrofa 30616 R-SSC-2029473 https://reactome.org/PathwayBrowser/#/R-SSC-2029473 Branching and elongation of mother and daughter filaments IEA Sus scrofa 30616 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa 30616 R-SSC-203070 https://reactome.org/PathwayBrowser/#/R-SSC-203070 Association of profilin with monomeric actin IEA Sus scrofa 30616 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 30616 R-SSC-2046085 https://reactome.org/PathwayBrowser/#/R-SSC-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Sus scrofa 30616 R-SSC-2046087 https://reactome.org/PathwayBrowser/#/R-SSC-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Sus scrofa 30616 R-SSC-2046093 https://reactome.org/PathwayBrowser/#/R-SSC-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Sus scrofa 30616 R-SSC-2046098 https://reactome.org/PathwayBrowser/#/R-SSC-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Sus scrofa 30616 R-SSC-205075 https://reactome.org/PathwayBrowser/#/R-SSC-205075 JNK phosphorylates BIM, BAD and other targets IEA Sus scrofa 30616 R-SSC-205136 https://reactome.org/PathwayBrowser/#/R-SSC-205136 GTP-bound RAC contributes to JNK activation IEA Sus scrofa 30616 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 30616 R-SSC-2060328 https://reactome.org/PathwayBrowser/#/R-SSC-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Sus scrofa 30616 R-SSC-209087 https://reactome.org/PathwayBrowser/#/R-SSC-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Sus scrofa 30616 R-SSC-210291 https://reactome.org/PathwayBrowser/#/R-SSC-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Sus scrofa 30616 R-SSC-212710 https://reactome.org/PathwayBrowser/#/R-SSC-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Sus scrofa 30616 R-SSC-2130194 https://reactome.org/PathwayBrowser/#/R-SSC-2130194 ABL phosphorylates WAVEs IEA Sus scrofa 30616 R-SSC-2162073 https://reactome.org/PathwayBrowser/#/R-SSC-2162073 carbovir monophosphate + ATP => carbovir diphosphate + ADP TAS Sus scrofa 30616 R-SSC-216723 https://reactome.org/PathwayBrowser/#/R-SSC-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Sus scrofa 30616 R-SSC-216757 https://reactome.org/PathwayBrowser/#/R-SSC-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Sus scrofa 30616 R-SSC-2168079 https://reactome.org/PathwayBrowser/#/R-SSC-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Sus scrofa 30616 R-SSC-2176475 https://reactome.org/PathwayBrowser/#/R-SSC-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Sus scrofa 30616 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa 30616 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa 30616 R-SSC-2214351 https://reactome.org/PathwayBrowser/#/R-SSC-2214351 PLK1 phosphorylates GORASP1 IEA Sus scrofa 30616 R-SSC-2267372 https://reactome.org/PathwayBrowser/#/R-SSC-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Sus scrofa 30616 R-SSC-2294580 https://reactome.org/PathwayBrowser/#/R-SSC-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Sus scrofa 30616 R-SSC-2294600 https://reactome.org/PathwayBrowser/#/R-SSC-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Sus scrofa 30616 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-2395412 https://reactome.org/PathwayBrowser/#/R-SSC-2395412 Phosphorylation of SYK IEA Sus scrofa 30616 R-SSC-2395801 https://reactome.org/PathwayBrowser/#/R-SSC-2395801 Phosphorylation of LAT by p-SYK IEA Sus scrofa 30616 R-SSC-2396002 https://reactome.org/PathwayBrowser/#/R-SSC-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex IEA Sus scrofa 30616 R-SSC-2396007 https://reactome.org/PathwayBrowser/#/R-SSC-2396007 IRF3 is phosphorylated by TBK1 IEA Sus scrofa 30616 R-SSC-2396594 https://reactome.org/PathwayBrowser/#/R-SSC-2396594 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa 30616 R-SSC-2404193 https://reactome.org/PathwayBrowser/#/R-SSC-2404193 IGF1R phosphorylates SHC1 IEA Sus scrofa 30616 R-SSC-2404199 https://reactome.org/PathwayBrowser/#/R-SSC-2404199 IGF1,2:IGF1R autophosphorylates IEA Sus scrofa 30616 R-SSC-2408551 https://reactome.org/PathwayBrowser/#/R-SSC-2408551 SeMet is converted to AdoSeMet by MAT IEA Sus scrofa 30616 R-SSC-2422927 https://reactome.org/PathwayBrowser/#/R-SSC-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Sus scrofa 30616 R-SSC-2424480 https://reactome.org/PathwayBrowser/#/R-SSC-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-2424484 https://reactome.org/PathwayBrowser/#/R-SSC-2424484 Phosphorylation of BTK by p-SYK IEA Sus scrofa 30616 R-SSC-2424486 https://reactome.org/PathwayBrowser/#/R-SSC-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Sus scrofa 30616 R-SSC-2424487 https://reactome.org/PathwayBrowser/#/R-SSC-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Sus scrofa 30616 R-SSC-2428926 https://reactome.org/PathwayBrowser/#/R-SSC-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Sus scrofa 30616 R-SSC-2430535 https://reactome.org/PathwayBrowser/#/R-SSC-2430535 MASTL phosphorylates ENSA IEA Sus scrofa 30616 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa 30616 R-SSC-2466068 https://reactome.org/PathwayBrowser/#/R-SSC-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Sus scrofa 30616 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa 30616 R-SSC-2468293 https://reactome.org/PathwayBrowser/#/R-SSC-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Sus scrofa 30616 R-SSC-2529020 https://reactome.org/PathwayBrowser/#/R-SSC-2529020 CK2 phosphorylates condensin I subunits IEA Sus scrofa 30616 R-SSC-2562526 https://reactome.org/PathwayBrowser/#/R-SSC-2562526 PLK1 phosphorylates OPTN IEA Sus scrofa 30616 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa 30616 R-SSC-2581474 https://reactome.org/PathwayBrowser/#/R-SSC-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Sus scrofa 30616 R-SSC-265682 https://reactome.org/PathwayBrowser/#/R-SSC-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Sus scrofa 30616 R-SSC-265783 https://reactome.org/PathwayBrowser/#/R-SSC-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-266082 https://reactome.org/PathwayBrowser/#/R-SSC-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Sus scrofa 30616 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa 30616 R-SSC-2730835 https://reactome.org/PathwayBrowser/#/R-SSC-2730835 Autophosphorylation of PKC-theta IEA Sus scrofa 30616 R-SSC-2730841 https://reactome.org/PathwayBrowser/#/R-SSC-2730841 Phosphorylation and activation of VAV IEA Sus scrofa 30616 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa 30616 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa 30616 R-SSC-2730856 https://reactome.org/PathwayBrowser/#/R-SSC-2730856 Autophosphorylation of PAK IEA Sus scrofa 30616 R-SSC-2730858 https://reactome.org/PathwayBrowser/#/R-SSC-2730858 Autophosphorylation of BTK/ITK IEA Sus scrofa 30616 R-SSC-2730862 https://reactome.org/PathwayBrowser/#/R-SSC-2730862 Autophosphorylation of LYN kinase IEA Sus scrofa 30616 R-SSC-2730863 https://reactome.org/PathwayBrowser/#/R-SSC-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Sus scrofa 30616 R-SSC-2730870 https://reactome.org/PathwayBrowser/#/R-SSC-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Sus scrofa 30616 R-SSC-2730876 https://reactome.org/PathwayBrowser/#/R-SSC-2730876 Phosphorylation of IKK-beta by TAK1 IEA Sus scrofa 30616 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa 30616 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa 30616 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa 30616 R-SSC-2730896 https://reactome.org/PathwayBrowser/#/R-SSC-2730896 Phosphorylation of MEK4 by MEKK1 IEA Sus scrofa 30616 R-SSC-2730900 https://reactome.org/PathwayBrowser/#/R-SSC-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Sus scrofa 30616 R-SSC-2730904 https://reactome.org/PathwayBrowser/#/R-SSC-2730904 Auto-ubiquitination of TRAF6 IEA Sus scrofa 30616 R-SSC-2855020 https://reactome.org/PathwayBrowser/#/R-SSC-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Sus scrofa 30616 R-SSC-2984220 https://reactome.org/PathwayBrowser/#/R-SSC-2984220 CDK1:CCNB phosphorylates NEK9 IEA Sus scrofa 30616 R-SSC-2984226 https://reactome.org/PathwayBrowser/#/R-SSC-2984226 PLK1 phosphorylates NEK9 IEA Sus scrofa 30616 R-SSC-2984258 https://reactome.org/PathwayBrowser/#/R-SSC-2984258 NEK9 phosphorylates NEK6/NEK7 IEA Sus scrofa 30616 R-SSC-2990833 https://reactome.org/PathwayBrowser/#/R-SSC-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Sus scrofa 30616 R-SSC-2990880 https://reactome.org/PathwayBrowser/#/R-SSC-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Sus scrofa 30616 R-SSC-2990882 https://reactome.org/PathwayBrowser/#/R-SSC-2990882 CDK1 phosphorylates NUP98 IEA Sus scrofa 30616 R-SSC-2993447 https://reactome.org/PathwayBrowser/#/R-SSC-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Sus scrofa 30616 R-SSC-2993799 https://reactome.org/PathwayBrowser/#/R-SSC-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Sus scrofa 30616 R-SSC-2993802 https://reactome.org/PathwayBrowser/#/R-SSC-2993802 HLCS biotinylates PC:Mn2+ IEA Sus scrofa 30616 R-SSC-2993814 https://reactome.org/PathwayBrowser/#/R-SSC-2993814 HLCS biotinylates ACACA:Mn2+ IEA Sus scrofa 30616 R-SSC-2993898 https://reactome.org/PathwayBrowser/#/R-SSC-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Sus scrofa 30616 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa 30616 R-SSC-3000327 https://reactome.org/PathwayBrowser/#/R-SSC-3000327 PLK1 phosphorylates BORA IEA Sus scrofa 30616 R-SSC-3095901 https://reactome.org/PathwayBrowser/#/R-SSC-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Sus scrofa 30616 R-SSC-3132737 https://reactome.org/PathwayBrowser/#/R-SSC-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Sus scrofa 30616 R-SSC-3159253 https://reactome.org/PathwayBrowser/#/R-SSC-3159253 MMAB adenosylates cob(I)alamin IEA Sus scrofa 30616 R-SSC-3222006 https://reactome.org/PathwayBrowser/#/R-SSC-3222006 STK11 (LKB1) phosphorylates NUAK1 IEA Sus scrofa 30616 R-SSC-3222020 https://reactome.org/PathwayBrowser/#/R-SSC-3222020 NUAK1 phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-3228469 https://reactome.org/PathwayBrowser/#/R-SSC-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Sus scrofa 30616 R-SSC-3229102 https://reactome.org/PathwayBrowser/#/R-SSC-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Sus scrofa 30616 R-SSC-3238999 https://reactome.org/PathwayBrowser/#/R-SSC-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Sus scrofa 30616 R-SSC-3239014 https://reactome.org/PathwayBrowser/#/R-SSC-3239014 MAPKAPK5 phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-3239019 https://reactome.org/PathwayBrowser/#/R-SSC-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Sus scrofa 30616 R-SSC-3249371 https://reactome.org/PathwayBrowser/#/R-SSC-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Sus scrofa 30616 R-SSC-3249379 https://reactome.org/PathwayBrowser/#/R-SSC-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Sus scrofa 30616 R-SSC-3249390 https://reactome.org/PathwayBrowser/#/R-SSC-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Sus scrofa 30616 R-SSC-3371422 https://reactome.org/PathwayBrowser/#/R-SSC-3371422 ATP hydrolysis by HSP70 IEA Sus scrofa 30616 R-SSC-3371435 https://reactome.org/PathwayBrowser/#/R-SSC-3371435 Constitutive phosphorylation by GSK3 IEA Sus scrofa 30616 R-SSC-3371531 https://reactome.org/PathwayBrowser/#/R-SSC-3371531 Constitutive phosphorylation by pERK1/2 IEA Sus scrofa 30616 R-SSC-3371590 https://reactome.org/PathwayBrowser/#/R-SSC-3371590 HSP70 binds to HSP40:nascent protein IEA Sus scrofa 30616 R-SSC-349444 https://reactome.org/PathwayBrowser/#/R-SSC-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Sus scrofa 30616 R-SSC-354073 https://reactome.org/PathwayBrowser/#/R-SSC-354073 Autophosphorylation of PTK2 at Y397 IEA Sus scrofa 30616 R-SSC-354124 https://reactome.org/PathwayBrowser/#/R-SSC-354124 Phosphorylation of pPTK2 by SRC IEA Sus scrofa 30616 R-SSC-372693 https://reactome.org/PathwayBrowser/#/R-SSC-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Sus scrofa 30616 R-SSC-373747 https://reactome.org/PathwayBrowser/#/R-SSC-373747 Phosphorylation of nephrin by FYN IEA Sus scrofa 30616 R-SSC-373750 https://reactome.org/PathwayBrowser/#/R-SSC-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Sus scrofa 30616 R-SSC-374664 https://reactome.org/PathwayBrowser/#/R-SSC-374664 Phosphorylation and activation of Ezrin IEA Sus scrofa 30616 R-SSC-3772435 https://reactome.org/PathwayBrowser/#/R-SSC-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Sus scrofa 30616 R-SSC-3772436 https://reactome.org/PathwayBrowser/#/R-SSC-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Sus scrofa 30616 R-SSC-377640 https://reactome.org/PathwayBrowser/#/R-SSC-377640 Autophosphorylation of SRC IEA Sus scrofa 30616 R-SSC-3788705 https://reactome.org/PathwayBrowser/#/R-SSC-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa 30616 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 30616 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 30616 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa 30616 R-SSC-380278 https://reactome.org/PathwayBrowser/#/R-SSC-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Sus scrofa 30616 R-SSC-380780 https://reactome.org/PathwayBrowser/#/R-SSC-380780 Activation of Src IEA Sus scrofa 30616 R-SSC-380927 https://reactome.org/PathwayBrowser/#/R-SSC-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Sus scrofa 30616 R-SSC-381111 https://reactome.org/PathwayBrowser/#/R-SSC-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Sus scrofa 30616 R-SSC-382553 https://reactome.org/PathwayBrowser/#/R-SSC-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Sus scrofa 30616 R-SSC-382560 https://reactome.org/PathwayBrowser/#/R-SSC-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Sus scrofa 30616 R-SSC-382575 https://reactome.org/PathwayBrowser/#/R-SSC-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Sus scrofa 30616 R-SSC-383190 https://reactome.org/PathwayBrowser/#/R-SSC-383190 HCO3- transport through ion channel IEA Sus scrofa 30616 R-SSC-3857329 https://reactome.org/PathwayBrowser/#/R-SSC-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Sus scrofa 30616 R-SSC-388831 https://reactome.org/PathwayBrowser/#/R-SSC-388831 Phosphorylation of CD28 IEA Sus scrofa 30616 R-SSC-388833 https://reactome.org/PathwayBrowser/#/R-SSC-388833 Phosphorylation of CTLA-4 IEA Sus scrofa 30616 R-SSC-389083 https://reactome.org/PathwayBrowser/#/R-SSC-389083 Autophosphorylation of PDGF alpha receptors IEA Sus scrofa 30616 R-SSC-389086 https://reactome.org/PathwayBrowser/#/R-SSC-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Sus scrofa 30616 R-SSC-389158 https://reactome.org/PathwayBrowser/#/R-SSC-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-389354 https://reactome.org/PathwayBrowser/#/R-SSC-389354 Activation of Vav1 IEA Sus scrofa 30616 R-SSC-389622 https://reactome.org/PathwayBrowser/#/R-SSC-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 30616 R-SSC-389632 https://reactome.org/PathwayBrowser/#/R-SSC-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 30616 R-SSC-389652 https://reactome.org/PathwayBrowser/#/R-SSC-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Sus scrofa 30616 R-SSC-389762 https://reactome.org/PathwayBrowser/#/R-SSC-389762 Phosphorylation of PD-1 IEA Sus scrofa 30616 R-SSC-390593 https://reactome.org/PathwayBrowser/#/R-SSC-390593 ATP Hydrolysis By Myosin IEA Sus scrofa 30616 R-SSC-390598 https://reactome.org/PathwayBrowser/#/R-SSC-390598 Myosin Binds ATP IEA Sus scrofa 30616 R-SSC-392300 https://reactome.org/PathwayBrowser/#/R-SSC-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-392530 https://reactome.org/PathwayBrowser/#/R-SSC-392530 p-S400-Cot phosphorylates NIK IEA Sus scrofa 30616 R-SSC-3928578 https://reactome.org/PathwayBrowser/#/R-SSC-3928578 EPH receptors autophosphorylate IEA Sus scrofa 30616 R-SSC-3928595 https://reactome.org/PathwayBrowser/#/R-SSC-3928595 N-WASP binds ARP2/3 and G-actin IEA Sus scrofa 30616 R-SSC-3928604 https://reactome.org/PathwayBrowser/#/R-SSC-3928604 SFKs phosphorylate VAV2,3 IEA Sus scrofa 30616 R-SSC-3928620 https://reactome.org/PathwayBrowser/#/R-SSC-3928620 PAK1 autophosphorylates IEA Sus scrofa 30616 R-SSC-3928625 https://reactome.org/PathwayBrowser/#/R-SSC-3928625 PAKs autophosphorylate IEA Sus scrofa 30616 R-SSC-3928627 https://reactome.org/PathwayBrowser/#/R-SSC-3928627 EPHB phosphorylates TIAM1 IEA Sus scrofa 30616 R-SSC-3928640 https://reactome.org/PathwayBrowser/#/R-SSC-3928640 PAKs phosphorylate MLC IEA Sus scrofa 30616 R-SSC-399939 https://reactome.org/PathwayBrowser/#/R-SSC-399939 Autophosphorylation of PAK IEA Sus scrofa 30616 R-SSC-399944 https://reactome.org/PathwayBrowser/#/R-SSC-399944 Phosphorylation of CRMPs by Cdk5 IEA Sus scrofa 30616 R-SSC-399947 https://reactome.org/PathwayBrowser/#/R-SSC-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Sus scrofa 30616 R-SSC-399951 https://reactome.org/PathwayBrowser/#/R-SSC-399951 Phosphorylation of CRMPs by GSK3beta IEA Sus scrofa 30616 R-SSC-399952 https://reactome.org/PathwayBrowser/#/R-SSC-399952 Phosphorylation of LIMK-1 by PAK IEA Sus scrofa 30616 R-SSC-399978 https://reactome.org/PathwayBrowser/#/R-SSC-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Sus scrofa 30616 R-SSC-4085028 https://reactome.org/PathwayBrowser/#/R-SSC-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Sus scrofa 30616 R-SSC-4086410 https://reactome.org/PathwayBrowser/#/R-SSC-4086410 CDK1 phosphorylates BORA IEA Sus scrofa 30616 R-SSC-4088024 https://reactome.org/PathwayBrowser/#/R-SSC-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Sus scrofa 30616 R-SSC-4088134 https://reactome.org/PathwayBrowser/#/R-SSC-4088134 PLK1 phosphorylates FOXM1 IEA Sus scrofa 30616 R-SSC-4093332 https://reactome.org/PathwayBrowser/#/R-SSC-4093332 p-EPHB phosphorylates SDC2 IEA Sus scrofa 30616 R-SSC-416320 https://reactome.org/PathwayBrowser/#/R-SSC-416320 Trafficking of GluR1-containing AMPA receptors IEA Sus scrofa 30616 R-SSC-416639 https://reactome.org/PathwayBrowser/#/R-SSC-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Sus scrofa 30616 R-SSC-4167511 https://reactome.org/PathwayBrowser/#/R-SSC-4167511 HLCS biotinylates ACACB IEA Sus scrofa 30616 R-SSC-416985 https://reactome.org/PathwayBrowser/#/R-SSC-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Sus scrofa 30616 R-SSC-417825 https://reactome.org/PathwayBrowser/#/R-SSC-417825 P2Y11 receptor can bind to ATP IEA Sus scrofa 30616 R-SSC-417927 https://reactome.org/PathwayBrowser/#/R-SSC-417927 P2Y2 receptor binds ATP and UTP IEA Sus scrofa 30616 R-SSC-418845 https://reactome.org/PathwayBrowser/#/R-SSC-418845 Activation of caspase-3 IEA Sus scrofa 30616 R-SSC-419490 https://reactome.org/PathwayBrowser/#/R-SSC-419490 Binding of ATP to P2X receptors IEA Sus scrofa 30616 R-SSC-419644 https://reactome.org/PathwayBrowser/#/R-SSC-419644 Transphosphorylation of pLIMK1 IEA Sus scrofa 30616 R-SSC-419646 https://reactome.org/PathwayBrowser/#/R-SSC-419646 SEMA4D interacts with Plexin-B1:Met IEA Sus scrofa 30616 R-SSC-421007 https://reactome.org/PathwayBrowser/#/R-SSC-421007 Endocytosis of Ca impermeable AMPA receptors IEA Sus scrofa 30616 R-SSC-426240 https://reactome.org/PathwayBrowser/#/R-SSC-426240 DAG kinase produces phosphatidic acid from DAG IEA Sus scrofa 30616 R-SSC-428273 https://reactome.org/PathwayBrowser/#/R-SSC-428273 SPHK1 phosphorylates sphingoid IEA Sus scrofa 30616 R-SSC-428941 https://reactome.org/PathwayBrowser/#/R-SSC-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Sus scrofa 30616 R-SSC-428961 https://reactome.org/PathwayBrowser/#/R-SSC-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Sus scrofa 30616 R-SSC-429016 https://reactome.org/PathwayBrowser/#/R-SSC-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Sus scrofa 30616 R-SSC-429157 https://reactome.org/PathwayBrowser/#/R-SSC-429157 ABCC4 accumulation of dense granule contents IEA Sus scrofa 30616 R-SSC-429441 https://reactome.org/PathwayBrowser/#/R-SSC-429441 SYK activation by SRC IEA Sus scrofa 30616 R-SSC-429449 https://reactome.org/PathwayBrowser/#/R-SSC-429449 Syk activation leads to SLP-76 activation IEA Sus scrofa 30616 R-SSC-430347 https://reactome.org/PathwayBrowser/#/R-SSC-430347 MigFilin associates with Filamin and F-actin IEA Sus scrofa 30616 R-SSC-432129 https://reactome.org/PathwayBrowser/#/R-SSC-432129 FGR binds and phosphorylates LRP8 IEA Sus scrofa 30616 R-SSC-432148 https://reactome.org/PathwayBrowser/#/R-SSC-432148 Fgr may phosphorylate p38 MAPK IEA Sus scrofa 30616 R-SSC-432232 https://reactome.org/PathwayBrowser/#/R-SSC-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Sus scrofa 30616 R-SSC-4332358 https://reactome.org/PathwayBrowser/#/R-SSC-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Sus scrofa 30616 R-SSC-4332363 https://reactome.org/PathwayBrowser/#/R-SSC-4332363 Autophosphorylation and activation of CAMK2 IEA Sus scrofa 30616 R-SSC-434382 https://reactome.org/PathwayBrowser/#/R-SSC-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Sus scrofa 30616 R-SSC-434836 https://reactome.org/PathwayBrowser/#/R-SSC-434836 Syk/Lck phosphorylate LAT IEA Sus scrofa 30616 R-SSC-435244 https://reactome.org/PathwayBrowser/#/R-SSC-435244 PECAM1 is phosphorylated IEA Sus scrofa 30616 R-SSC-437162 https://reactome.org/PathwayBrowser/#/R-SSC-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-4411383 https://reactome.org/PathwayBrowser/#/R-SSC-4411383 NLK phosphorylates TCF/LEF IEA Sus scrofa 30616 R-SSC-4411402 https://reactome.org/PathwayBrowser/#/R-SSC-4411402 Activation of NLK IEA Sus scrofa 30616 R-SSC-4420117 https://reactome.org/PathwayBrowser/#/R-SSC-4420117 VEGFR2 autophosphorylates IEA Sus scrofa 30616 R-SSC-4420121 https://reactome.org/PathwayBrowser/#/R-SSC-4420121 SFKs phosphorylate PLCG1 IEA Sus scrofa 30616 R-SSC-4420128 https://reactome.org/PathwayBrowser/#/R-SSC-4420128 SRC-1 phosphorylates SHB IEA Sus scrofa 30616 R-SSC-4420206 https://reactome.org/PathwayBrowser/#/R-SSC-4420206 Phosphorylation of SRC-1 IEA Sus scrofa 30616 R-SSC-442724 https://reactome.org/PathwayBrowser/#/R-SSC-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Sus scrofa 30616 R-SSC-442749 https://reactome.org/PathwayBrowser/#/R-SSC-442749 CaMKK autophosphorylates in the nucleus IEA Sus scrofa 30616 R-SSC-445072 https://reactome.org/PathwayBrowser/#/R-SSC-445072 Interaction of PAK1 with Rac1-GTP IEA Sus scrofa 30616 R-SSC-445079 https://reactome.org/PathwayBrowser/#/R-SSC-445079 Phosphorylation of L1 by ERK IEA Sus scrofa 30616 R-SSC-445699 https://reactome.org/PathwayBrowser/#/R-SSC-445699 ATP Hydrolysis By Myosin IEA Sus scrofa 30616 R-SSC-445700 https://reactome.org/PathwayBrowser/#/R-SSC-445700 Myosin Binds ATP IEA Sus scrofa 30616 R-SSC-445813 https://reactome.org/PathwayBrowser/#/R-SSC-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Sus scrofa 30616 R-SSC-446634 https://reactome.org/PathwayBrowser/#/R-SSC-446634 IRAK4 is activated by autophosphorylation IEA Sus scrofa 30616 R-SSC-446694 https://reactome.org/PathwayBrowser/#/R-SSC-446694 IRAK4 phosphorylates IRAK1 IEA Sus scrofa 30616 R-SSC-446701 https://reactome.org/PathwayBrowser/#/R-SSC-446701 IRAK4-activated IRAK1 autophosphorylates IEA Sus scrofa 30616 R-SSC-447074 https://reactome.org/PathwayBrowser/#/R-SSC-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Sus scrofa 30616 R-SSC-448955 https://reactome.org/PathwayBrowser/#/R-SSC-448955 Phosphorylation of MEF2 proteins by p38 IEA Sus scrofa 30616 R-SSC-449911 https://reactome.org/PathwayBrowser/#/R-SSC-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Sus scrofa 30616 R-SSC-450088 https://reactome.org/PathwayBrowser/#/R-SSC-450088 GLUT1 tetramer binds 4xATP IEA Sus scrofa 30616 R-SSC-450092 https://reactome.org/PathwayBrowser/#/R-SSC-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Sus scrofa 30616 R-SSC-450222 https://reactome.org/PathwayBrowser/#/R-SSC-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Sus scrofa 30616 R-SSC-450325 https://reactome.org/PathwayBrowser/#/R-SSC-450325 c-FOS activation by phospho ERK1/2 IEA Sus scrofa 30616 R-SSC-450333 https://reactome.org/PathwayBrowser/#/R-SSC-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Sus scrofa 30616 R-SSC-450337 https://reactome.org/PathwayBrowser/#/R-SSC-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Sus scrofa 30616 R-SSC-450346 https://reactome.org/PathwayBrowser/#/R-SSC-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Sus scrofa 30616 R-SSC-450463 https://reactome.org/PathwayBrowser/#/R-SSC-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Sus scrofa 30616 R-SSC-450474 https://reactome.org/PathwayBrowser/#/R-SSC-450474 MK2 phosphorylates BRF1 IEA Sus scrofa 30616 R-SSC-450533 https://reactome.org/PathwayBrowser/#/R-SSC-450533 PKCdelta phosphorylates HuR IEA Sus scrofa 30616 R-SSC-450550 https://reactome.org/PathwayBrowser/#/R-SSC-450550 PKCalpha phosphorylates HuR IEA Sus scrofa 30616 R-SSC-450827 https://reactome.org/PathwayBrowser/#/R-SSC-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Sus scrofa 30616 R-SSC-451942 https://reactome.org/PathwayBrowser/#/R-SSC-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Sus scrofa 30616 R-SSC-452097 https://reactome.org/PathwayBrowser/#/R-SSC-452097 Recruited STAT5 is phosphorylated IEA Sus scrofa 30616 R-SSC-452100 https://reactome.org/PathwayBrowser/#/R-SSC-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Sus scrofa 30616 R-SSC-452122 https://reactome.org/PathwayBrowser/#/R-SSC-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Sus scrofa 30616 R-SSC-453200 https://reactome.org/PathwayBrowser/#/R-SSC-453200 SYK autophosphorylates IEA Sus scrofa 30616 R-SSC-453342 https://reactome.org/PathwayBrowser/#/R-SSC-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Sus scrofa 30616 R-SSC-4793911 https://reactome.org/PathwayBrowser/#/R-SSC-4793911 MAPKAPK2 phosphorylates HSF1 IEA Sus scrofa 30616 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 30616 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 30616 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 30616 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 30616 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 30616 R-SSC-504054 https://reactome.org/PathwayBrowser/#/R-SSC-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Sus scrofa 30616 R-SSC-508040 https://reactome.org/PathwayBrowser/#/R-SSC-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Sus scrofa 30616 R-SSC-5082387 https://reactome.org/PathwayBrowser/#/R-SSC-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Sus scrofa 30616 R-SSC-5082405 https://reactome.org/PathwayBrowser/#/R-SSC-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Sus scrofa 30616 R-SSC-508282 https://reactome.org/PathwayBrowser/#/R-SSC-508282 SYK is a substrate for JAK1 IEA Sus scrofa 30616 R-SSC-508308 https://reactome.org/PathwayBrowser/#/R-SSC-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Sus scrofa 30616 R-SSC-5138432 https://reactome.org/PathwayBrowser/#/R-SSC-5138432 DVL2 is phosphorylated by PKC IEA Sus scrofa 30616 R-SSC-5195402 https://reactome.org/PathwayBrowser/#/R-SSC-5195402 CDK1 phosphorylates LPIN IEA Sus scrofa 30616 R-SSC-5213464 https://reactome.org/PathwayBrowser/#/R-SSC-5213464 RIPK1 is phosphorylated IEA Sus scrofa 30616 R-SSC-5213466 https://reactome.org/PathwayBrowser/#/R-SSC-5213466 RIPK3 is phosphorylated IEA Sus scrofa 30616 R-SSC-5218640 https://reactome.org/PathwayBrowser/#/R-SSC-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Sus scrofa 30616 R-SSC-5218642 https://reactome.org/PathwayBrowser/#/R-SSC-5218642 PTK2 autophosphorylates IEA Sus scrofa 30616 R-SSC-5218804 https://reactome.org/PathwayBrowser/#/R-SSC-5218804 p38 MAPK activation by VEGFR IEA Sus scrofa 30616 R-SSC-5218805 https://reactome.org/PathwayBrowser/#/R-SSC-5218805 PKC autophosphorylates IEA Sus scrofa 30616 R-SSC-5218806 https://reactome.org/PathwayBrowser/#/R-SSC-5218806 FYN autophosphorylates IEA Sus scrofa 30616 R-SSC-5218809 https://reactome.org/PathwayBrowser/#/R-SSC-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Sus scrofa 30616 R-SSC-5218812 https://reactome.org/PathwayBrowser/#/R-SSC-5218812 FYN phosphorylates PAK2 IEA Sus scrofa 30616 R-SSC-5218814 https://reactome.org/PathwayBrowser/#/R-SSC-5218814 PAK2 autophorylates IEA Sus scrofa 30616 R-SSC-5218819 https://reactome.org/PathwayBrowser/#/R-SSC-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-5218820 https://reactome.org/PathwayBrowser/#/R-SSC-5218820 Src kinases phosphorylate VAV IEA Sus scrofa 30616 R-SSC-5218821 https://reactome.org/PathwayBrowser/#/R-SSC-5218821 PDK1 phosphorylates PKC IEA Sus scrofa 30616 R-SSC-5218823 https://reactome.org/PathwayBrowser/#/R-SSC-5218823 PKC phosphorylates sphingosine kinase 1 IEA Sus scrofa 30616 R-SSC-5218826 https://reactome.org/PathwayBrowser/#/R-SSC-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Sus scrofa 30616 R-SSC-5218830 https://reactome.org/PathwayBrowser/#/R-SSC-5218830 SRC-1 phosphorylates PTK2-beta IEA Sus scrofa 30616 R-SSC-5218845 https://reactome.org/PathwayBrowser/#/R-SSC-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Sus scrofa 30616 R-SSC-5218851 https://reactome.org/PathwayBrowser/#/R-SSC-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Sus scrofa 30616 R-SSC-5218854 https://reactome.org/PathwayBrowser/#/R-SSC-5218854 p-Y420-FYN is phosphorylated on S21 IEA Sus scrofa 30616 R-SSC-5218906 https://reactome.org/PathwayBrowser/#/R-SSC-5218906 RIPK3 phosphorylates MLKL IEA Sus scrofa 30616 R-SSC-5218916 https://reactome.org/PathwayBrowser/#/R-SSC-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Sus scrofa 30616 R-SSC-5223313 https://reactome.org/PathwayBrowser/#/R-SSC-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Sus scrofa 30616 R-SSC-5223317 https://reactome.org/PathwayBrowser/#/R-SSC-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Sus scrofa 30616 R-SSC-5229194 https://reactome.org/PathwayBrowser/#/R-SSC-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Sus scrofa 30616 R-SSC-5229343 https://reactome.org/PathwayBrowser/#/R-SSC-5229343 AXIN is phosphorylated in the destruction complex IEA Sus scrofa 30616 R-SSC-5244669 https://reactome.org/PathwayBrowser/#/R-SSC-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Sus scrofa 30616 R-SSC-5251942 https://reactome.org/PathwayBrowser/#/R-SSC-5251942 Hikeshi binds HSP70s:ATP IEA Sus scrofa 30616 R-SSC-5251955 https://reactome.org/PathwayBrowser/#/R-SSC-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Sus scrofa 30616 R-SSC-5251959 https://reactome.org/PathwayBrowser/#/R-SSC-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Sus scrofa 30616 R-SSC-5251989 https://reactome.org/PathwayBrowser/#/R-SSC-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Sus scrofa 30616 R-SSC-5252041 https://reactome.org/PathwayBrowser/#/R-SSC-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Sus scrofa 30616 R-SSC-5252079 https://reactome.org/PathwayBrowser/#/R-SSC-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Sus scrofa 30616 R-SSC-5339524 https://reactome.org/PathwayBrowser/#/R-SSC-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Sus scrofa 30616 R-SSC-5357429 https://reactome.org/PathwayBrowser/#/R-SSC-5357429 AXL autophosphorylates on Y779 and Y821 IEA Sus scrofa 30616 R-SSC-5357472 https://reactome.org/PathwayBrowser/#/R-SSC-5357472 PAK1-3 autophosphorylates IEA Sus scrofa 30616 R-SSC-5357477 https://reactome.org/PathwayBrowser/#/R-SSC-5357477 PAK1-3 phosphorylates VE-cadherin IEA Sus scrofa 30616 R-SSC-5357831 https://reactome.org/PathwayBrowser/#/R-SSC-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Sus scrofa 30616 R-SSC-5358475 https://reactome.org/PathwayBrowser/#/R-SSC-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Sus scrofa 30616 R-SSC-5358510 https://reactome.org/PathwayBrowser/#/R-SSC-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Sus scrofa 30616 R-SSC-5358518 https://reactome.org/PathwayBrowser/#/R-SSC-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Sus scrofa 30616 R-SSC-5358592 https://reactome.org/PathwayBrowser/#/R-SSC-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Sus scrofa 30616 R-SSC-5358597 https://reactome.org/PathwayBrowser/#/R-SSC-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Sus scrofa 30616 R-SSC-5358599 https://reactome.org/PathwayBrowser/#/R-SSC-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Sus scrofa 30616 R-SSC-5358912 https://reactome.org/PathwayBrowser/#/R-SSC-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Sus scrofa 30616 R-SSC-5362459 https://reactome.org/PathwayBrowser/#/R-SSC-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Sus scrofa 30616 R-SSC-548843 https://reactome.org/PathwayBrowser/#/R-SSC-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Sus scrofa 30616 R-SSC-5578777 https://reactome.org/PathwayBrowser/#/R-SSC-5578777 DMPK phosphorylates PLN IEA Sus scrofa 30616 R-SSC-5603114 https://reactome.org/PathwayBrowser/#/R-SSC-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Sus scrofa 30616 R-SSC-5607722 https://reactome.org/PathwayBrowser/#/R-SSC-5607722 Active NIK phosphorylates IKKA dimer IEA Sus scrofa 30616 R-SSC-5607726 https://reactome.org/PathwayBrowser/#/R-SSC-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Sus scrofa 30616 R-SSC-5607732 https://reactome.org/PathwayBrowser/#/R-SSC-5607732 K63polyUb-TAK1 autophosphorylates IEA Sus scrofa 30616 R-SSC-5607740 https://reactome.org/PathwayBrowser/#/R-SSC-5607740 PKC-delta phosphorylates CARD9 IEA Sus scrofa 30616 R-SSC-5607742 https://reactome.org/PathwayBrowser/#/R-SSC-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Sus scrofa 30616 R-SSC-5607750 https://reactome.org/PathwayBrowser/#/R-SSC-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Sus scrofa 30616 R-SSC-5607756 https://reactome.org/PathwayBrowser/#/R-SSC-5607756 TRAF6 oligomer autoubiquitinates IEA Sus scrofa 30616 R-SSC-5607757 https://reactome.org/PathwayBrowser/#/R-SSC-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 IEA Sus scrofa 30616 R-SSC-5610720 https://reactome.org/PathwayBrowser/#/R-SSC-5610720 PKA phosphorylates GLI3 IEA Sus scrofa 30616 R-SSC-5610722 https://reactome.org/PathwayBrowser/#/R-SSC-5610722 CK1 phosphorylates p-GLI3 IEA Sus scrofa 30616 R-SSC-5610727 https://reactome.org/PathwayBrowser/#/R-SSC-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Sus scrofa 30616 R-SSC-5610732 https://reactome.org/PathwayBrowser/#/R-SSC-5610732 GSK3 phosphorylates p-GLI3 IEA Sus scrofa 30616 R-SSC-5617179 https://reactome.org/PathwayBrowser/#/R-SSC-5617179 PRKACA phosphorylates TNNI3 IEA Sus scrofa 30616 R-SSC-5617182 https://reactome.org/PathwayBrowser/#/R-SSC-5617182 PRKACA phosphorylates PLN IEA Sus scrofa 30616 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 30616 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 30616 R-SSC-5618085 https://reactome.org/PathwayBrowser/#/R-SSC-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Sus scrofa 30616 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 30616 R-SSC-5618098 https://reactome.org/PathwayBrowser/#/R-SSC-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Sus scrofa 30616 R-SSC-5618099 https://reactome.org/PathwayBrowser/#/R-SSC-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Sus scrofa 30616 R-SSC-5618105 https://reactome.org/PathwayBrowser/#/R-SSC-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Sus scrofa 30616 R-SSC-5618107 https://reactome.org/PathwayBrowser/#/R-SSC-5618107 ATP binding to HSP90 triggers conformation change IEA Sus scrofa 30616 R-SSC-5618110 https://reactome.org/PathwayBrowser/#/R-SSC-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Sus scrofa 30616 R-SSC-5621355 https://reactome.org/PathwayBrowser/#/R-SSC-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Sus scrofa 30616 R-SSC-5621363 https://reactome.org/PathwayBrowser/#/R-SSC-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Sus scrofa 30616 R-SSC-5621370 https://reactome.org/PathwayBrowser/#/R-SSC-5621370 SYK autophosphorylates IEA Sus scrofa 30616 R-SSC-5623667 https://reactome.org/PathwayBrowser/#/R-SSC-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Sus scrofa 30616 R-SSC-5624473 https://reactome.org/PathwayBrowser/#/R-SSC-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Sus scrofa 30616 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa 30616 R-SSC-5626507 https://reactome.org/PathwayBrowser/#/R-SSC-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Sus scrofa 30616 R-SSC-5627775 https://reactome.org/PathwayBrowser/#/R-SSC-5627775 Autophosphorylation of PAK1,2,3 IEA Sus scrofa 30616 R-SSC-5635842 https://reactome.org/PathwayBrowser/#/R-SSC-5635842 ULK3 phosphorylates GLI IEA Sus scrofa 30616 R-SSC-5654149 https://reactome.org/PathwayBrowser/#/R-SSC-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Sus scrofa 30616 R-SSC-5654151 https://reactome.org/PathwayBrowser/#/R-SSC-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Sus scrofa 30616 R-SSC-5654418 https://reactome.org/PathwayBrowser/#/R-SSC-5654418 Activated FGFR4 phosphorylates FRS2 IEA Sus scrofa 30616 R-SSC-5654428 https://reactome.org/PathwayBrowser/#/R-SSC-5654428 Activated FGFR4 phosphorylates SHC1 IEA Sus scrofa 30616 R-SSC-5654560 https://reactome.org/PathwayBrowser/#/R-SSC-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Sus scrofa 30616 R-SSC-5654566 https://reactome.org/PathwayBrowser/#/R-SSC-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Sus scrofa 30616 R-SSC-5654575 https://reactome.org/PathwayBrowser/#/R-SSC-5654575 Activated FGFR1 phosphorylates FRS2 IEA Sus scrofa 30616 R-SSC-5654578 https://reactome.org/PathwayBrowser/#/R-SSC-5654578 Activated FGFR1 phosphorylates FRS3 IEA Sus scrofa 30616 R-SSC-5654582 https://reactome.org/PathwayBrowser/#/R-SSC-5654582 Activated FGFR1 phosphorylates SHC1 IEA Sus scrofa 30616 R-SSC-5654587 https://reactome.org/PathwayBrowser/#/R-SSC-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Sus scrofa 30616 R-SSC-5654607 https://reactome.org/PathwayBrowser/#/R-SSC-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Sus scrofa 30616 R-SSC-5654631 https://reactome.org/PathwayBrowser/#/R-SSC-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Sus scrofa 30616 R-SSC-5654653 https://reactome.org/PathwayBrowser/#/R-SSC-5654653 Activated FGFR4 phosphorylates FRS3 IEA Sus scrofa 30616 R-SSC-5654655 https://reactome.org/PathwayBrowser/#/R-SSC-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Sus scrofa 30616 R-SSC-5654690 https://reactome.org/PathwayBrowser/#/R-SSC-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-5654692 https://reactome.org/PathwayBrowser/#/R-SSC-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-5654697 https://reactome.org/PathwayBrowser/#/R-SSC-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-5654701 https://reactome.org/PathwayBrowser/#/R-SSC-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-5654705 https://reactome.org/PathwayBrowser/#/R-SSC-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-5654709 https://reactome.org/PathwayBrowser/#/R-SSC-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-5654714 https://reactome.org/PathwayBrowser/#/R-SSC-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-5654717 https://reactome.org/PathwayBrowser/#/R-SSC-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-5654989 https://reactome.org/PathwayBrowser/#/R-SSC-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Sus scrofa 30616 R-SSC-5662466 https://reactome.org/PathwayBrowser/#/R-SSC-5662466 XYLB phosphorylates D-xylulose IEA Sus scrofa 30616 R-SSC-5665751 https://reactome.org/PathwayBrowser/#/R-SSC-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin IEA Sus scrofa 30616 R-SSC-5665767 https://reactome.org/PathwayBrowser/#/R-SSC-5665767 Activated FMNL3 binds G-actin IEA Sus scrofa 30616 R-SSC-5665802 https://reactome.org/PathwayBrowser/#/R-SSC-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Sus scrofa 30616 R-SSC-5665809 https://reactome.org/PathwayBrowser/#/R-SSC-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Sus scrofa 30616 R-SSC-5665868 https://reactome.org/PathwayBrowser/#/R-SSC-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Sus scrofa 30616 R-SSC-5665982 https://reactome.org/PathwayBrowser/#/R-SSC-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 IEA Sus scrofa 30616 R-SSC-5666001 https://reactome.org/PathwayBrowser/#/R-SSC-5666001 Profilin:G-actin binds MKL1 IEA Sus scrofa 30616 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa 30616 R-SSC-5668545 https://reactome.org/PathwayBrowser/#/R-SSC-5668545 NIK autophosphorylates on T559 IEA Sus scrofa 30616 R-SSC-5668932 https://reactome.org/PathwayBrowser/#/R-SSC-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Sus scrofa 30616 R-SSC-5668947 https://reactome.org/PathwayBrowser/#/R-SSC-5668947 PAK1 phosphorylates myosin phosphatase IEA Sus scrofa 30616 R-SSC-5668984 https://reactome.org/PathwayBrowser/#/R-SSC-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Sus scrofa 30616 R-SSC-5669250 https://reactome.org/PathwayBrowser/#/R-SSC-5669250 PAK1 phosphorylates FLNA IEA Sus scrofa 30616 R-SSC-5671749 https://reactome.org/PathwayBrowser/#/R-SSC-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Sus scrofa 30616 R-SSC-5671763 https://reactome.org/PathwayBrowser/#/R-SSC-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Sus scrofa 30616 R-SSC-5672008 https://reactome.org/PathwayBrowser/#/R-SSC-5672008 Thr-180 of ULK1 is phosphorylated IEA Sus scrofa 30616 R-SSC-5672010 https://reactome.org/PathwayBrowser/#/R-SSC-5672010 Active MTORC1 phosphorylates ULK1 IEA Sus scrofa 30616 R-SSC-5672012 https://reactome.org/PathwayBrowser/#/R-SSC-5672012 Beclin-1 complex phosphorylates PtdIns IEA Sus scrofa 30616 R-SSC-5672027 https://reactome.org/PathwayBrowser/#/R-SSC-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Sus scrofa 30616 R-SSC-5672828 https://reactome.org/PathwayBrowser/#/R-SSC-5672828 mTORC1 phosphorylates AKT1S1 IEA Sus scrofa 30616 R-SSC-5672948 https://reactome.org/PathwayBrowser/#/R-SSC-5672948 MARK3 phosphorylates KSR1 IEA Sus scrofa 30616 R-SSC-5672969 https://reactome.org/PathwayBrowser/#/R-SSC-5672969 Phosphorylation of RAF IEA Sus scrofa 30616 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 30616 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 30616 R-SSC-5673768 https://reactome.org/PathwayBrowser/#/R-SSC-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Sus scrofa 30616 R-SSC-5674130 https://reactome.org/PathwayBrowser/#/R-SSC-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Sus scrofa 30616 R-SSC-5674373 https://reactome.org/PathwayBrowser/#/R-SSC-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Sus scrofa 30616 R-SSC-5675198 https://reactome.org/PathwayBrowser/#/R-SSC-5675198 Activated MAPKs phosphorylate BRAF IEA Sus scrofa 30616 R-SSC-5675868 https://reactome.org/PathwayBrowser/#/R-SSC-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Sus scrofa 30616 R-SSC-5678706 https://reactome.org/PathwayBrowser/#/R-SSC-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Sus scrofa 30616 R-SSC-5678863 https://reactome.org/PathwayBrowser/#/R-SSC-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-5679041 https://reactome.org/PathwayBrowser/#/R-SSC-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-5679205 https://reactome.org/PathwayBrowser/#/R-SSC-5679205 ULK1 phosphorylates Beclin-1 IEA Sus scrofa 30616 R-SSC-5682026 https://reactome.org/PathwayBrowser/#/R-SSC-5682026 MRN bound to shortened telomeres activates ATM IEA Sus scrofa 30616 R-SSC-5682101 https://reactome.org/PathwayBrowser/#/R-SSC-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Sus scrofa 30616 R-SSC-5682285 https://reactome.org/PathwayBrowser/#/R-SSC-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-5682598 https://reactome.org/PathwayBrowser/#/R-SSC-5682598 ATM phosphorylates HERC2 IEA Sus scrofa 30616 R-SSC-5682983 https://reactome.org/PathwayBrowser/#/R-SSC-5682983 ATM phosphorylates WHSC1 IEA Sus scrofa 30616 R-SSC-5683425 https://reactome.org/PathwayBrowser/#/R-SSC-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Sus scrofa 30616 R-SSC-5683714 https://reactome.org/PathwayBrowser/#/R-SSC-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Sus scrofa 30616 R-SSC-5683792 https://reactome.org/PathwayBrowser/#/R-SSC-5683792 p-T68-CHEK2 autophosphorylates IEA Sus scrofa 30616 R-SSC-5683801 https://reactome.org/PathwayBrowser/#/R-SSC-5683801 CHEK2 phosphorylates BRCA1 IEA Sus scrofa 30616 R-SSC-5683964 https://reactome.org/PathwayBrowser/#/R-SSC-5683964 ATM phosphorylates EYA1-4 IEA Sus scrofa 30616 R-SSC-5684096 https://reactome.org/PathwayBrowser/#/R-SSC-5684096 CDK2 phosphorylates RBBP8 IEA Sus scrofa 30616 R-SSC-5684140 https://reactome.org/PathwayBrowser/#/R-SSC-5684140 ATM phosphorylates RBBP8 IEA Sus scrofa 30616 R-SSC-5684261 https://reactome.org/PathwayBrowser/#/R-SSC-5684261 MAP3K8 is phosphorylated IEA Sus scrofa 30616 R-SSC-5684267 https://reactome.org/PathwayBrowser/#/R-SSC-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex IEA Sus scrofa 30616 R-SSC-5684275 https://reactome.org/PathwayBrowser/#/R-SSC-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 IEA Sus scrofa 30616 R-SSC-5684806 https://reactome.org/PathwayBrowser/#/R-SSC-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN IEA Sus scrofa 30616 R-SSC-5684862 https://reactome.org/PathwayBrowser/#/R-SSC-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Sus scrofa 30616 R-SSC-5684887 https://reactome.org/PathwayBrowser/#/R-SSC-5684887 Activation of CHEK1 at resected DNA DSBs IEA Sus scrofa 30616 R-SSC-5685156 https://reactome.org/PathwayBrowser/#/R-SSC-5685156 ATR phosphorylates RPA2 IEA Sus scrofa 30616 R-SSC-5685230 https://reactome.org/PathwayBrowser/#/R-SSC-5685230 CHEK1 phosphorylates RAD51 IEA Sus scrofa 30616 R-SSC-5686578 https://reactome.org/PathwayBrowser/#/R-SSC-5686578 Activated ATM phosphorylates ABL1 IEA Sus scrofa 30616 R-SSC-5686587 https://reactome.org/PathwayBrowser/#/R-SSC-5686587 ABL1 phosphorylates RAD52 IEA Sus scrofa 30616 R-SSC-5686704 https://reactome.org/PathwayBrowser/#/R-SSC-5686704 Activated ATM phosphorylates DCLRE1C IEA Sus scrofa 30616 R-SSC-5687086 https://reactome.org/PathwayBrowser/#/R-SSC-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Sus scrofa 30616 R-SSC-5687088 https://reactome.org/PathwayBrowser/#/R-SSC-5687088 PKA phosphorylates MAPKAPK5 IEA Sus scrofa 30616 R-SSC-5687090 https://reactome.org/PathwayBrowser/#/R-SSC-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Sus scrofa 30616 R-SSC-5687094 https://reactome.org/PathwayBrowser/#/R-SSC-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Sus scrofa 30616 R-SSC-5687101 https://reactome.org/PathwayBrowser/#/R-SSC-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Sus scrofa 30616 R-SSC-5687121 https://reactome.org/PathwayBrowser/#/R-SSC-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Sus scrofa 30616 R-SSC-5687183 https://reactome.org/PathwayBrowser/#/R-SSC-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Sus scrofa 30616 R-SSC-5690250 https://reactome.org/PathwayBrowser/#/R-SSC-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Sus scrofa 30616 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa 30616 R-SSC-5690996 https://reactome.org/PathwayBrowser/#/R-SSC-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Sus scrofa 30616 R-SSC-5692462 https://reactome.org/PathwayBrowser/#/R-SSC-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Sus scrofa 30616 R-SSC-5692480 https://reactome.org/PathwayBrowser/#/R-SSC-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Sus scrofa 30616 R-SSC-5692755 https://reactome.org/PathwayBrowser/#/R-SSC-5692755 CDK1 phosphorylates MAPK6 IEA Sus scrofa 30616 R-SSC-5692775 https://reactome.org/PathwayBrowser/#/R-SSC-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Sus scrofa 30616 R-SSC-5692779 https://reactome.org/PathwayBrowser/#/R-SSC-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Sus scrofa 30616 R-SSC-5693148 https://reactome.org/PathwayBrowser/#/R-SSC-5693148 BCKDK phosphorylates BCKDH IEA Sus scrofa 30616 R-SSC-5693536 https://reactome.org/PathwayBrowser/#/R-SSC-5693536 ATM phosphorylates MDC1 IEA Sus scrofa 30616 R-SSC-5693540 https://reactome.org/PathwayBrowser/#/R-SSC-5693540 MRN activates ATM IEA Sus scrofa 30616 R-SSC-5693549 https://reactome.org/PathwayBrowser/#/R-SSC-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Sus scrofa 30616 R-SSC-5693551 https://reactome.org/PathwayBrowser/#/R-SSC-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Sus scrofa 30616 R-SSC-5693575 https://reactome.org/PathwayBrowser/#/R-SSC-5693575 DNA-PKcs autophosphorylates IEA Sus scrofa 30616 R-SSC-5693598 https://reactome.org/PathwayBrowser/#/R-SSC-5693598 ATM phosphorylates NBN IEA Sus scrofa 30616 R-SSC-5693609 https://reactome.org/PathwayBrowser/#/R-SSC-5693609 ATM phosphorylates TP53 at S15 IEA Sus scrofa 30616 R-SSC-5694425 https://reactome.org/PathwayBrowser/#/R-SSC-5694425 NSF ATPase activity dissociates cis-SNARE IEA Sus scrofa 30616 R-SSC-5694494 https://reactome.org/PathwayBrowser/#/R-SSC-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Sus scrofa 30616 R-SSC-5695957 https://reactome.org/PathwayBrowser/#/R-SSC-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Sus scrofa 30616 R-SSC-5696004 https://reactome.org/PathwayBrowser/#/R-SSC-5696004 ACSF2 ligates CoA-SH to MCFA IEA Sus scrofa 30616 R-SSC-5696007 https://reactome.org/PathwayBrowser/#/R-SSC-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Sus scrofa 30616 R-SSC-5696074 https://reactome.org/PathwayBrowser/#/R-SSC-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Sus scrofa 30616 R-SSC-5696839 https://reactome.org/PathwayBrowser/#/R-SSC-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Sus scrofa 30616 R-SSC-6782131 https://reactome.org/PathwayBrowser/#/R-SSC-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa 30616 R-SSC-6784006 https://reactome.org/PathwayBrowser/#/R-SSC-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Sus scrofa 30616 R-SSC-6784319 https://reactome.org/PathwayBrowser/#/R-SSC-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Sus scrofa 30616 R-SSC-6784324 https://reactome.org/PathwayBrowser/#/R-SSC-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Sus scrofa 30616 R-SSC-6786050 https://reactome.org/PathwayBrowser/#/R-SSC-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Sus scrofa 30616 R-SSC-6786095 https://reactome.org/PathwayBrowser/#/R-SSC-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Sus scrofa 30616 R-SSC-6786096 https://reactome.org/PathwayBrowser/#/R-SSC-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Sus scrofa 30616 R-SSC-6786245 https://reactome.org/PathwayBrowser/#/R-SSC-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Sus scrofa 30616 R-SSC-6787540 https://reactome.org/PathwayBrowser/#/R-SSC-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Sus scrofa 30616 R-SSC-6788392 https://reactome.org/PathwayBrowser/#/R-SSC-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Sus scrofa 30616 R-SSC-6788582 https://reactome.org/PathwayBrowser/#/R-SSC-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Sus scrofa 30616 R-SSC-6788798 https://reactome.org/PathwayBrowser/#/R-SSC-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 30616 R-SSC-6788810 https://reactome.org/PathwayBrowser/#/R-SSC-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 30616 R-SSC-6788855 https://reactome.org/PathwayBrowser/#/R-SSC-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Sus scrofa 30616 R-SSC-6788867 https://reactome.org/PathwayBrowser/#/R-SSC-6788867 FN3K phosphorylates ketosamines IEA Sus scrofa 30616 R-SSC-6793661 https://reactome.org/PathwayBrowser/#/R-SSC-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Sus scrofa 30616 R-SSC-6795290 https://reactome.org/PathwayBrowser/#/R-SSC-6795290 TORC2 complex phosphorylates SGK1 IEA Sus scrofa 30616 R-SSC-6795460 https://reactome.org/PathwayBrowser/#/R-SSC-6795460 SGK1 phosphorylates MDM2 IEA Sus scrofa 30616 R-SSC-6795473 https://reactome.org/PathwayBrowser/#/R-SSC-6795473 PDPK1 phosphorylates SGK1 IEA Sus scrofa 30616 R-SSC-6797606 https://reactome.org/PathwayBrowser/#/R-SSC-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Sus scrofa 30616 R-SSC-6798174 https://reactome.org/PathwayBrowser/#/R-SSC-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Sus scrofa 30616 R-SSC-6798372 https://reactome.org/PathwayBrowser/#/R-SSC-6798372 ATM phosphorylates DYRK2 IEA Sus scrofa 30616 R-SSC-6798374 https://reactome.org/PathwayBrowser/#/R-SSC-6798374 DYRK2 phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6799097 https://reactome.org/PathwayBrowser/#/R-SSC-6799097 ATM phosphorylates ZNF420 IEA Sus scrofa 30616 R-SSC-6799246 https://reactome.org/PathwayBrowser/#/R-SSC-6799246 CHEK1 phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6799332 https://reactome.org/PathwayBrowser/#/R-SSC-6799332 ATR phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6799409 https://reactome.org/PathwayBrowser/#/R-SSC-6799409 HIPK2 phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6799495 https://reactome.org/PathwayBrowser/#/R-SSC-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Sus scrofa 30616 R-SSC-6800490 https://reactome.org/PathwayBrowser/#/R-SSC-6800490 ATM phosphorylates PIDD1 IEA Sus scrofa 30616 R-SSC-6801342 https://reactome.org/PathwayBrowser/#/R-SSC-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Sus scrofa 30616 R-SSC-6801456 https://reactome.org/PathwayBrowser/#/R-SSC-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Sus scrofa 30616 R-SSC-6801666 https://reactome.org/PathwayBrowser/#/R-SSC-6801666 PLK2 phosphorylates CENPJ IEA Sus scrofa 30616 R-SSC-6801675 https://reactome.org/PathwayBrowser/#/R-SSC-6801675 PLK2 phosphorylates NPM1 IEA Sus scrofa 30616 R-SSC-6802973 https://reactome.org/PathwayBrowser/#/R-SSC-6802973 PLK3 phosphorylates CDC25C IEA Sus scrofa 30616 R-SSC-6803545 https://reactome.org/PathwayBrowser/#/R-SSC-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Sus scrofa 30616 R-SSC-6803771 https://reactome.org/PathwayBrowser/#/R-SSC-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Sus scrofa 30616 R-SSC-6804266 https://reactome.org/PathwayBrowser/#/R-SSC-6804266 CHEK2 phosphorylates TTC5 IEA Sus scrofa 30616 R-SSC-6804276 https://reactome.org/PathwayBrowser/#/R-SSC-6804276 ATM phosphorylates TTC5 IEA Sus scrofa 30616 R-SSC-6804596 https://reactome.org/PathwayBrowser/#/R-SSC-6804596 APAF1:CYCS binds APIP IEA Sus scrofa 30616 R-SSC-6804955 https://reactome.org/PathwayBrowser/#/R-SSC-6804955 ATM phosphorylates MDM2 IEA Sus scrofa 30616 R-SSC-6805059 https://reactome.org/PathwayBrowser/#/R-SSC-6805059 CK2:FACT phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6805103 https://reactome.org/PathwayBrowser/#/R-SSC-6805103 AURKA phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6805109 https://reactome.org/PathwayBrowser/#/R-SSC-6805109 CDK2 phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6805126 https://reactome.org/PathwayBrowser/#/R-SSC-6805126 AURKB phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6805276 https://reactome.org/PathwayBrowser/#/R-SSC-6805276 CDK5 phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6805285 https://reactome.org/PathwayBrowser/#/R-SSC-6805285 PLK3 phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6805399 https://reactome.org/PathwayBrowser/#/R-SSC-6805399 TAF1 phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6805470 https://reactome.org/PathwayBrowser/#/R-SSC-6805470 AMPK phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6805479 https://reactome.org/PathwayBrowser/#/R-SSC-6805479 TP53RK phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-6806877 https://reactome.org/PathwayBrowser/#/R-SSC-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Sus scrofa 30616 R-SSC-6806967 https://reactome.org/PathwayBrowser/#/R-SSC-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Sus scrofa 30616 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 30616 R-SSC-6807868 https://reactome.org/PathwayBrowser/#/R-SSC-6807868 GBF1 stimulates ARF nucleotide exchange IEA Sus scrofa 30616 R-SSC-6809015 https://reactome.org/PathwayBrowser/#/R-SSC-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Sus scrofa 30616 R-SSC-6810233 https://reactome.org/PathwayBrowser/#/R-SSC-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Sus scrofa 30616 R-SSC-6811422 https://reactome.org/PathwayBrowser/#/R-SSC-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Sus scrofa 30616 R-SSC-6811454 https://reactome.org/PathwayBrowser/#/R-SSC-6811454 MAPKs phosphorylate PP2A IEA Sus scrofa 30616 R-SSC-6811522 https://reactome.org/PathwayBrowser/#/R-SSC-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Sus scrofa 30616 R-SSC-6814120 https://reactome.org/PathwayBrowser/#/R-SSC-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Sus scrofa 30616 R-SSC-6814124 https://reactome.org/PathwayBrowser/#/R-SSC-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Sus scrofa 30616 R-SSC-6814409 https://reactome.org/PathwayBrowser/#/R-SSC-6814409 CK2 phosphorylates PDCL IEA Sus scrofa 30616 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa 30616 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa 30616 R-SSC-68610 https://reactome.org/PathwayBrowser/#/R-SSC-68610 Formation of ORC(2-5) complex IEA Sus scrofa 30616 R-SSC-68944 https://reactome.org/PathwayBrowser/#/R-SSC-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Sus scrofa 30616 R-SSC-68954 https://reactome.org/PathwayBrowser/#/R-SSC-68954 Mcm2-7 is phosphorylated by DDK IEA Sus scrofa 30616 R-SSC-69005 https://reactome.org/PathwayBrowser/#/R-SSC-69005 Cdc6 protein is phosphorylated by CDK IEA Sus scrofa 30616 R-SSC-69015 https://reactome.org/PathwayBrowser/#/R-SSC-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Sus scrofa 30616 R-SSC-69063 https://reactome.org/PathwayBrowser/#/R-SSC-69063 Loading of PCNA - Sliding Clamp Formation IEA Sus scrofa 30616 R-SSC-69195 https://reactome.org/PathwayBrowser/#/R-SSC-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Sus scrofa 30616 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 30616 R-SSC-69604 https://reactome.org/PathwayBrowser/#/R-SSC-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Sus scrofa 30616 R-SSC-69608 https://reactome.org/PathwayBrowser/#/R-SSC-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Sus scrofa 30616 R-SSC-69685 https://reactome.org/PathwayBrowser/#/R-SSC-69685 CHEK2 phosphorylates TP53 IEA Sus scrofa 30616 R-SSC-69891 https://reactome.org/PathwayBrowser/#/R-SSC-69891 Phosphorylation and activation of CHEK2 by ATM IEA Sus scrofa 30616 R-SSC-70333 https://reactome.org/PathwayBrowser/#/R-SSC-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Sus scrofa 30616 R-SSC-70349 https://reactome.org/PathwayBrowser/#/R-SSC-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Sus scrofa 30616 R-SSC-70355 https://reactome.org/PathwayBrowser/#/R-SSC-70355 GALK1 phosphorylates Gal to Gal1P IEA Sus scrofa 30616 R-SSC-70420 https://reactome.org/PathwayBrowser/#/R-SSC-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Sus scrofa 30616 R-SSC-70467 https://reactome.org/PathwayBrowser/#/R-SSC-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Sus scrofa 30616 R-SSC-70486 https://reactome.org/PathwayBrowser/#/R-SSC-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Sus scrofa 30616 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 30616 R-SSC-70555 https://reactome.org/PathwayBrowser/#/R-SSC-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Sus scrofa 30616 R-SSC-70577 https://reactome.org/PathwayBrowser/#/R-SSC-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Sus scrofa 30616 R-SSC-70599 https://reactome.org/PathwayBrowser/#/R-SSC-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Sus scrofa 30616 R-SSC-70606 https://reactome.org/PathwayBrowser/#/R-SSC-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Sus scrofa 30616 R-SSC-70773 https://reactome.org/PathwayBrowser/#/R-SSC-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Sus scrofa 30616 R-SSC-70967 https://reactome.org/PathwayBrowser/#/R-SSC-70967 IDH3 complex decarboxylates isocitrate IEA Sus scrofa 30616 R-SSC-70997 https://reactome.org/PathwayBrowser/#/R-SSC-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Sus scrofa 30616 R-SSC-71031 https://reactome.org/PathwayBrowser/#/R-SSC-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Sus scrofa 30616 R-SSC-71401 https://reactome.org/PathwayBrowser/#/R-SSC-71401 OGDH dimer decarboxylates 2-OG IEA Sus scrofa 30616 R-SSC-71541 https://reactome.org/PathwayBrowser/#/R-SSC-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Sus scrofa 30616 R-SSC-71588 https://reactome.org/PathwayBrowser/#/R-SSC-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Sus scrofa 30616 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 30616 R-SSC-71735 https://reactome.org/PathwayBrowser/#/R-SSC-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Sus scrofa 30616 R-SSC-71802 https://reactome.org/PathwayBrowser/#/R-SSC-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Sus scrofa 30616 R-SSC-71850 https://reactome.org/PathwayBrowser/#/R-SSC-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Sus scrofa 30616 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa 30616 R-SSC-72185 https://reactome.org/PathwayBrowser/#/R-SSC-72185 mRNA polyadenylation IEA Sus scrofa 30616 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa 30616 R-SSC-727819 https://reactome.org/PathwayBrowser/#/R-SSC-727819 TAK1 phosphorylates MKK6 IEA Sus scrofa 30616 R-SSC-73548 https://reactome.org/PathwayBrowser/#/R-SSC-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Sus scrofa 30616 R-SSC-73577 https://reactome.org/PathwayBrowser/#/R-SSC-73577 CAD hexamer transforms L-Gln to CAP IEA Sus scrofa 30616 R-SSC-73580 https://reactome.org/PathwayBrowser/#/R-SSC-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Sus scrofa 30616 R-SSC-73599 https://reactome.org/PathwayBrowser/#/R-SSC-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Sus scrofa 30616 R-SSC-73632 https://reactome.org/PathwayBrowser/#/R-SSC-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Sus scrofa 30616 R-SSC-73635 https://reactome.org/PathwayBrowser/#/R-SSC-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Sus scrofa 30616 R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa 30616 R-SSC-73722 https://reactome.org/PathwayBrowser/#/R-SSC-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Sus scrofa 30616 R-SSC-73788 https://reactome.org/PathwayBrowser/#/R-SSC-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Sus scrofa 30616 R-SSC-73792 https://reactome.org/PathwayBrowser/#/R-SSC-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Sus scrofa 30616 R-SSC-73805 https://reactome.org/PathwayBrowser/#/R-SSC-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Sus scrofa 30616 R-SSC-73810 https://reactome.org/PathwayBrowser/#/R-SSC-73810 FGAM + ATP => AIR + ADP + Pi IEA Sus scrofa 30616 R-SSC-73814 https://reactome.org/PathwayBrowser/#/R-SSC-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Sus scrofa 30616 R-SSC-74207 https://reactome.org/PathwayBrowser/#/R-SSC-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Sus scrofa 30616 R-SSC-74220 https://reactome.org/PathwayBrowser/#/R-SSC-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Sus scrofa 30616 R-SSC-74711 https://reactome.org/PathwayBrowser/#/R-SSC-74711 Phosphorylation of IRS IEA Sus scrofa 30616 R-SSC-74715 https://reactome.org/PathwayBrowser/#/R-SSC-74715 Autophosphorylation of insulin receptor IEA Sus scrofa 30616 R-SSC-74742 https://reactome.org/PathwayBrowser/#/R-SSC-74742 Phosphorylation of SHC1 IEA Sus scrofa 30616 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 30616 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 30616 R-SSC-75010 https://reactome.org/PathwayBrowser/#/R-SSC-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Sus scrofa 30616 R-SSC-75125 https://reactome.org/PathwayBrowser/#/R-SSC-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Sus scrofa 30616 R-SSC-75126 https://reactome.org/PathwayBrowser/#/R-SSC-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Sus scrofa 30616 R-SSC-75809 https://reactome.org/PathwayBrowser/#/R-SSC-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Sus scrofa 30616 R-SSC-75848 https://reactome.org/PathwayBrowser/#/R-SSC-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Sus scrofa 30616 R-SSC-75851 https://reactome.org/PathwayBrowser/#/R-SSC-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 30616 R-SSC-75887 https://reactome.org/PathwayBrowser/#/R-SSC-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Sus scrofa 30616 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa 30616 R-SSC-77071 https://reactome.org/PathwayBrowser/#/R-SSC-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Sus scrofa 30616 R-SSC-873918 https://reactome.org/PathwayBrowser/#/R-SSC-873918 Transphosphorylation of JAK1 IEA Sus scrofa 30616 R-SSC-873919 https://reactome.org/PathwayBrowser/#/R-SSC-873919 Phosphorylation of JAK2 IEA Sus scrofa 30616 R-SSC-873922 https://reactome.org/PathwayBrowser/#/R-SSC-873922 Phosphorylation of STAT1 by JAK kinases IEA Sus scrofa 30616 R-SSC-873924 https://reactome.org/PathwayBrowser/#/R-SSC-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Sus scrofa 30616 R-SSC-877187 https://reactome.org/PathwayBrowser/#/R-SSC-877187 P2X7 mediates loss of intracellular K+ IEA Sus scrofa 30616 R-SSC-877198 https://reactome.org/PathwayBrowser/#/R-SSC-877198 P2X7 mediates membrane pores that include pannexin-1 IEA Sus scrofa 30616 R-SSC-879907 https://reactome.org/PathwayBrowser/#/R-SSC-879907 Tyrosine kinases phosphorylate the receptor IEA Sus scrofa 30616 R-SSC-879909 https://reactome.org/PathwayBrowser/#/R-SSC-879909 Activation of STAT5a/b by JAK2 IEA Sus scrofa 30616 R-SSC-879910 https://reactome.org/PathwayBrowser/#/R-SSC-879910 JAK2 is phosphorylated, activated IEA Sus scrofa 30616 R-SSC-8847638 https://reactome.org/PathwayBrowser/#/R-SSC-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Sus scrofa 30616 R-SSC-8847977 https://reactome.org/PathwayBrowser/#/R-SSC-8847977 FRK phosphorylates PTEN IEA Sus scrofa 30616 R-SSC-8848005 https://reactome.org/PathwayBrowser/#/R-SSC-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Sus scrofa 30616 R-SSC-8848053 https://reactome.org/PathwayBrowser/#/R-SSC-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Sus scrofa 30616 R-SSC-8848077 https://reactome.org/PathwayBrowser/#/R-SSC-8848077 PTK6 phosphorylates STAP2 IEA Sus scrofa 30616 R-SSC-8848124 https://reactome.org/PathwayBrowser/#/R-SSC-8848124 PTK6 phosphorylates STAT3 IEA Sus scrofa 30616 R-SSC-8848436 https://reactome.org/PathwayBrowser/#/R-SSC-8848436 PTK6 phosphorylates CDKN1B IEA Sus scrofa 30616 R-SSC-8848606 https://reactome.org/PathwayBrowser/#/R-SSC-8848606 PTK6 phosphorylates PXN IEA Sus scrofa 30616 R-SSC-8848726 https://reactome.org/PathwayBrowser/#/R-SSC-8848726 PTK6 phosphorylates BCAR1 IEA Sus scrofa 30616 R-SSC-8848776 https://reactome.org/PathwayBrowser/#/R-SSC-8848776 PTK6 phosphorylates DOK1 IEA Sus scrofa 30616 R-SSC-8848818 https://reactome.org/PathwayBrowser/#/R-SSC-8848818 PTK6 phosphorylates CBL IEA Sus scrofa 30616 R-SSC-8848873 https://reactome.org/PathwayBrowser/#/R-SSC-8848873 PTK6 phosphorylates ARAP1 IEA Sus scrofa 30616 R-SSC-8848975 https://reactome.org/PathwayBrowser/#/R-SSC-8848975 PTK6 phosphorylates KHDRBS1 IEA Sus scrofa 30616 R-SSC-8849032 https://reactome.org/PathwayBrowser/#/R-SSC-8849032 PTK6 phosphorylates KHDRBS2 IEA Sus scrofa 30616 R-SSC-8849042 https://reactome.org/PathwayBrowser/#/R-SSC-8849042 PTK6 phosphorylates KHDRBS3 IEA Sus scrofa 30616 R-SSC-8849068 https://reactome.org/PathwayBrowser/#/R-SSC-8849068 PTK6 phosphorylates ARHGAP35 IEA Sus scrofa 30616 R-SSC-8849102 https://reactome.org/PathwayBrowser/#/R-SSC-8849102 SRMS phosphorylates PTK6 IEA Sus scrofa 30616 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa 30616 R-SSC-8849463 https://reactome.org/PathwayBrowser/#/R-SSC-8849463 PTK6 phosphorylates SFPQ IEA Sus scrofa 30616 R-SSC-8850945 https://reactome.org/PathwayBrowser/#/R-SSC-8850945 Casein kinase II phosphorylates PTEN IEA Sus scrofa 30616 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 30616 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 30616 R-SSC-8851797 https://reactome.org/PathwayBrowser/#/R-SSC-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Sus scrofa 30616 R-SSC-8851890 https://reactome.org/PathwayBrowser/#/R-SSC-8851890 MET phosphorylates SHC1-2 IEA Sus scrofa 30616 R-SSC-8851933 https://reactome.org/PathwayBrowser/#/R-SSC-8851933 MET phosphorylates GAB1 IEA Sus scrofa 30616 R-SSC-8852019 https://reactome.org/PathwayBrowser/#/R-SSC-8852019 MET bound PI3K generates PIP3 IEA Sus scrofa 30616 R-SSC-8852128 https://reactome.org/PathwayBrowser/#/R-SSC-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Sus scrofa 30616 R-SSC-8852131 https://reactome.org/PathwayBrowser/#/R-SSC-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Sus scrofa 30616 R-SSC-8852132 https://reactome.org/PathwayBrowser/#/R-SSC-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Sus scrofa 30616 R-SSC-8852134 https://reactome.org/PathwayBrowser/#/R-SSC-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Sus scrofa 30616 R-SSC-8852306 https://reactome.org/PathwayBrowser/#/R-SSC-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Sus scrofa 30616 R-SSC-8852317 https://reactome.org/PathwayBrowser/#/R-SSC-8852317 PLK1 phosphorylates GTSE1 IEA Sus scrofa 30616 R-SSC-8852552 https://reactome.org/PathwayBrowser/#/R-SSC-8852552 MST1R autophosphorylates IEA Sus scrofa 30616 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa 30616 R-SSC-8853444 https://reactome.org/PathwayBrowser/#/R-SSC-8853444 AURKA phosphorylates PHLDA1 IEA Sus scrofa 30616 R-SSC-8853774 https://reactome.org/PathwayBrowser/#/R-SSC-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Sus scrofa 30616 R-SSC-8853792 https://reactome.org/PathwayBrowser/#/R-SSC-8853792 RET tyrosine phosphorylation IEA Sus scrofa 30616 R-SSC-8854908 https://reactome.org/PathwayBrowser/#/R-SSC-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Sus scrofa 30616 R-SSC-8855237 https://reactome.org/PathwayBrowser/#/R-SSC-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Sus scrofa 30616 R-SSC-8856813 https://reactome.org/PathwayBrowser/#/R-SSC-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Sus scrofa 30616 R-SSC-8857555 https://reactome.org/PathwayBrowser/#/R-SSC-8857555 EGFR phosphorylates GPNMB IEA Sus scrofa 30616 R-SSC-8857577 https://reactome.org/PathwayBrowser/#/R-SSC-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Sus scrofa 30616 R-SSC-8857583 https://reactome.org/PathwayBrowser/#/R-SSC-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Sus scrofa 30616 R-SSC-8857925 https://reactome.org/PathwayBrowser/#/R-SSC-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Sus scrofa 30616 R-SSC-8865774 https://reactome.org/PathwayBrowser/#/R-SSC-8865774 TTLLs polyglutamylate tubulin IEA Sus scrofa 30616 R-SSC-8866268 https://reactome.org/PathwayBrowser/#/R-SSC-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Sus scrofa 30616 R-SSC-8866405 https://reactome.org/PathwayBrowser/#/R-SSC-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 30616 R-SSC-8866542 https://reactome.org/PathwayBrowser/#/R-SSC-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Sus scrofa 30616 R-SSC-8867041 https://reactome.org/PathwayBrowser/#/R-SSC-8867041 EGFR phosphorylates EPS15 IEA Sus scrofa 30616 R-SSC-8867370 https://reactome.org/PathwayBrowser/#/R-SSC-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Sus scrofa 30616 R-SSC-8868066 https://reactome.org/PathwayBrowser/#/R-SSC-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Sus scrofa 30616 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 30616 R-SSC-8868118 https://reactome.org/PathwayBrowser/#/R-SSC-8868118 MAPK12 phosphorylates PTPN3 IEA Sus scrofa 30616 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa 30616 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa 30616 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 30616 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa 30616 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 30616 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa 30616 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa 30616 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 30616 R-SSC-8869606 https://reactome.org/PathwayBrowser/#/R-SSC-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Sus scrofa 30616 R-SSC-8869607 https://reactome.org/PathwayBrowser/#/R-SSC-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Sus scrofa 30616 R-SSC-8869627 https://reactome.org/PathwayBrowser/#/R-SSC-8869627 NMRK2 phosphorylates NR to yield NMN IEA Sus scrofa 30616 R-SSC-8869633 https://reactome.org/PathwayBrowser/#/R-SSC-8869633 NMRK1 phosphorylates NR to yield NMN IEA Sus scrofa 30616 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 30616 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa 30616 R-SSC-8871373 https://reactome.org/PathwayBrowser/#/R-SSC-8871373 BMX phosphorylates RUFY1 IEA Sus scrofa 30616 R-SSC-8873929 https://reactome.org/PathwayBrowser/#/R-SSC-8873929 Casein kinase II phosphorylates STARD10 IEA Sus scrofa 30616 R-SSC-8874080 https://reactome.org/PathwayBrowser/#/R-SSC-8874080 SRC phosphorylates PTK2 IEA Sus scrofa 30616 R-SSC-8874082 https://reactome.org/PathwayBrowser/#/R-SSC-8874082 MET phosphorylates PTK2 IEA Sus scrofa 30616 R-SSC-8875071 https://reactome.org/PathwayBrowser/#/R-SSC-8875071 ACSS3 ligates CoA to CH3COO- IEA Sus scrofa 30616 R-SSC-8875451 https://reactome.org/PathwayBrowser/#/R-SSC-8875451 MET phosphorylates CBL IEA Sus scrofa 30616 R-SSC-8875817 https://reactome.org/PathwayBrowser/#/R-SSC-8875817 MET phosphorylates STAT3 IEA Sus scrofa 30616 R-SSC-8876446 https://reactome.org/PathwayBrowser/#/R-SSC-8876446 p-ULK1 phosphorylates DENND3 IEA Sus scrofa 30616 R-SSC-8876889 https://reactome.org/PathwayBrowser/#/R-SSC-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 30616 R-SSC-8877691 https://reactome.org/PathwayBrowser/#/R-SSC-8877691 MAP2K6 phosphorylates PIP4K2B IEA Sus scrofa 30616 R-SSC-8878050 https://reactome.org/PathwayBrowser/#/R-SSC-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Sus scrofa 30616 R-SSC-8878054 https://reactome.org/PathwayBrowser/#/R-SSC-8878054 HIPK2 phosphorylates RUNX1 IEA Sus scrofa 30616 R-SSC-8931653 https://reactome.org/PathwayBrowser/#/R-SSC-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Sus scrofa 30616 R-SSC-8934446 https://reactome.org/PathwayBrowser/#/R-SSC-8934446 Activated PKC phosphorylates SHC1 IEA Sus scrofa 30616 R-SSC-8937807 https://reactome.org/PathwayBrowser/#/R-SSC-8937807 SRC phosphorylates RUNX3 IEA Sus scrofa 30616 R-SSC-8939204 https://reactome.org/PathwayBrowser/#/R-SSC-8939204 ESTG binds ESR1:chaperone complex IEA Sus scrofa 30616 R-SSC-8939959 https://reactome.org/PathwayBrowser/#/R-SSC-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Sus scrofa 30616 R-SSC-8940100 https://reactome.org/PathwayBrowser/#/R-SSC-8940100 CDK1 phosphorylates VCPIP1 IEA Sus scrofa 30616 R-SSC-8942575 https://reactome.org/PathwayBrowser/#/R-SSC-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Sus scrofa 30616 R-SSC-8942607 https://reactome.org/PathwayBrowser/#/R-SSC-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Sus scrofa 30616 R-SSC-8942836 https://reactome.org/PathwayBrowser/#/R-SSC-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Sus scrofa 30616 R-SSC-8944454 https://reactome.org/PathwayBrowser/#/R-SSC-8944454 mTORC1 phosphorylates MAF1 IEA Sus scrofa 30616 R-SSC-8948039 https://reactome.org/PathwayBrowser/#/R-SSC-8948039 FUNDC1 is phosphorylated by CK2 IEA Sus scrofa 30616 R-SSC-8948143 https://reactome.org/PathwayBrowser/#/R-SSC-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Sus scrofa 30616 R-SSC-8948146 https://reactome.org/PathwayBrowser/#/R-SSC-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Sus scrofa 30616 R-SSC-8950269 https://reactome.org/PathwayBrowser/#/R-SSC-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Sus scrofa 30616 R-SSC-8950340 https://reactome.org/PathwayBrowser/#/R-SSC-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Sus scrofa 30616 R-SSC-8950405 https://reactome.org/PathwayBrowser/#/R-SSC-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Sus scrofa 30616 R-SSC-8950423 https://reactome.org/PathwayBrowser/#/R-SSC-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Sus scrofa 30616 R-SSC-8950453 https://reactome.org/PathwayBrowser/#/R-SSC-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Sus scrofa 30616 R-SSC-8950485 https://reactome.org/PathwayBrowser/#/R-SSC-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Sus scrofa 30616 R-SSC-8950537 https://reactome.org/PathwayBrowser/#/R-SSC-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Sus scrofa 30616 R-SSC-8950757 https://reactome.org/PathwayBrowser/#/R-SSC-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Sus scrofa 30616 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa 30616 R-SSC-8954327 https://reactome.org/PathwayBrowser/#/R-SSC-8954327 UCKL1 phosphorylates urindine, cytidine IEA Sus scrofa 30616 R-SSC-8955030 https://reactome.org/PathwayBrowser/#/R-SSC-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Sus scrofa 30616 R-SSC-8955844 https://reactome.org/PathwayBrowser/#/R-SSC-8955844 RBKS phosphorylates ribose to R5P IEA Sus scrofa 30616 R-SSC-8956659 https://reactome.org/PathwayBrowser/#/R-SSC-8956659 ABL1 phosphorylates YAP1 IEA Sus scrofa 30616 R-SSC-8959510 https://reactome.org/PathwayBrowser/#/R-SSC-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Sus scrofa 30616 R-SSC-8959719 https://reactome.org/PathwayBrowser/#/R-SSC-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Sus scrofa 30616 R-SSC-8964242 https://reactome.org/PathwayBrowser/#/R-SSC-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Sus scrofa 30616 R-SSC-8982163 https://reactome.org/PathwayBrowser/#/R-SSC-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Sus scrofa 30616 R-SSC-8983059 https://reactome.org/PathwayBrowser/#/R-SSC-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Sus scrofa 30616 R-SSC-8983063 https://reactome.org/PathwayBrowser/#/R-SSC-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Sus scrofa 30616 R-SSC-8983300 https://reactome.org/PathwayBrowser/#/R-SSC-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Sus scrofa 30616 R-SSC-8983371 https://reactome.org/PathwayBrowser/#/R-SSC-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Sus scrofa 30616 R-SSC-8983834 https://reactome.org/PathwayBrowser/#/R-SSC-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Sus scrofa 30616 R-SSC-8983835 https://reactome.org/PathwayBrowser/#/R-SSC-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Sus scrofa 30616 R-SSC-8983870 https://reactome.org/PathwayBrowser/#/R-SSC-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Sus scrofa 30616 R-SSC-8983872 https://reactome.org/PathwayBrowser/#/R-SSC-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Sus scrofa 30616 R-SSC-8984012 https://reactome.org/PathwayBrowser/#/R-SSC-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Sus scrofa 30616 R-SSC-8984014 https://reactome.org/PathwayBrowser/#/R-SSC-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Sus scrofa 30616 R-SSC-8985914 https://reactome.org/PathwayBrowser/#/R-SSC-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Sus scrofa 30616 R-SSC-8985973 https://reactome.org/PathwayBrowser/#/R-SSC-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Sus scrofa 30616 R-SSC-8985988 https://reactome.org/PathwayBrowser/#/R-SSC-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Sus scrofa 30616 R-SSC-8986985 https://reactome.org/PathwayBrowser/#/R-SSC-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Sus scrofa 30616 R-SSC-8986994 https://reactome.org/PathwayBrowser/#/R-SSC-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Sus scrofa 30616 R-SSC-8986995 https://reactome.org/PathwayBrowser/#/R-SSC-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Sus scrofa 30616 R-SSC-8987012 https://reactome.org/PathwayBrowser/#/R-SSC-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Sus scrofa 30616 R-SSC-8987040 https://reactome.org/PathwayBrowser/#/R-SSC-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Sus scrofa 30616 R-SSC-8987042 https://reactome.org/PathwayBrowser/#/R-SSC-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Sus scrofa 30616 R-SSC-8987070 https://reactome.org/PathwayBrowser/#/R-SSC-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Sus scrofa 30616 R-SSC-8987084 https://reactome.org/PathwayBrowser/#/R-SSC-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Sus scrofa 30616 R-SSC-8987096 https://reactome.org/PathwayBrowser/#/R-SSC-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Sus scrofa 30616 R-SSC-8987129 https://reactome.org/PathwayBrowser/#/R-SSC-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Sus scrofa 30616 R-SSC-8987141 https://reactome.org/PathwayBrowser/#/R-SSC-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Sus scrofa 30616 R-SSC-8987150 https://reactome.org/PathwayBrowser/#/R-SSC-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Sus scrofa 30616 R-SSC-8987179 https://reactome.org/PathwayBrowser/#/R-SSC-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Sus scrofa 30616 R-SSC-8987202 https://reactome.org/PathwayBrowser/#/R-SSC-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Sus scrofa 30616 R-SSC-8987255 https://reactome.org/PathwayBrowser/#/R-SSC-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Sus scrofa 30616 R-SSC-9006850 https://reactome.org/PathwayBrowser/#/R-SSC-9006850 IL21 receptor JAK phosphorylation IEA Sus scrofa 30616 R-SSC-9006870 https://reactome.org/PathwayBrowser/#/R-SSC-9006870 IL21 receptor STAT phosphorylation IEA Sus scrofa 30616 R-SSC-9007539 https://reactome.org/PathwayBrowser/#/R-SSC-9007539 CHEK1 phosphorylates E2F6 IEA Sus scrofa 30616 R-SSC-9008043 https://reactome.org/PathwayBrowser/#/R-SSC-9008043 MAPK8 phosphorylation IEA Sus scrofa 30616 R-SSC-9008412 https://reactome.org/PathwayBrowser/#/R-SSC-9008412 CDK4 phosphorylates RUNX2 IEA Sus scrofa 30616 R-SSC-9008684 https://reactome.org/PathwayBrowser/#/R-SSC-9008684 TBK1 phosphorylation IEA Sus scrofa 30616 R-SSC-9009072 https://reactome.org/PathwayBrowser/#/R-SSC-9009072 STAT3 phosphorylation IEA Sus scrofa 30616 R-SSC-9009282 https://reactome.org/PathwayBrowser/#/R-SSC-9009282 CDK1 phosphorylates RUNX2 IEA Sus scrofa 30616 R-SSC-9009936 https://reactome.org/PathwayBrowser/#/R-SSC-9009936 RNASEL cleaves cellular ssRNA IEA Sus scrofa 30616 R-SSC-9009950 https://reactome.org/PathwayBrowser/#/R-SSC-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Sus scrofa 30616 R-SSC-9012268 https://reactome.org/PathwayBrowser/#/R-SSC-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Sus scrofa 30616 R-SSC-9012319 https://reactome.org/PathwayBrowser/#/R-SSC-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Sus scrofa 30616 R-SSC-9014741 https://reactome.org/PathwayBrowser/#/R-SSC-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Sus scrofa 30616 R-SSC-9014766 https://reactome.org/PathwayBrowser/#/R-SSC-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Sus scrofa 30616 R-SSC-9021357 https://reactome.org/PathwayBrowser/#/R-SSC-9021357 PRKCI phosphorylates ELF3 IEA Sus scrofa 30616 R-SSC-9021609 https://reactome.org/PathwayBrowser/#/R-SSC-9021609 ESR-associated SRC autophosphorylates IEA Sus scrofa 30616 R-SSC-9021627 https://reactome.org/PathwayBrowser/#/R-SSC-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 30616 R-SSC-9022314 https://reactome.org/PathwayBrowser/#/R-SSC-9022314 HIPK2 phosphorylates MECP2 IEA Sus scrofa 30616 R-SSC-9027272 https://reactome.org/PathwayBrowser/#/R-SSC-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Sus scrofa 30616 R-SSC-9027273 https://reactome.org/PathwayBrowser/#/R-SSC-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Sus scrofa 30616 R-SSC-9033499 https://reactome.org/PathwayBrowser/#/R-SSC-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Sus scrofa 30616 R-SSC-9034714 https://reactome.org/PathwayBrowser/#/R-SSC-9034714 NTRK3 dimers trans-autophosphorylate IEA Sus scrofa 30616 R-SSC-9038161 https://reactome.org/PathwayBrowser/#/R-SSC-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Sus scrofa 30616 R-SSC-909552 https://reactome.org/PathwayBrowser/#/R-SSC-909552 Phosphorylation of STAT1 at Ser727 IEA Sus scrofa 30616 R-SSC-909718 https://reactome.org/PathwayBrowser/#/R-SSC-909718 Formation of p-STAT1 homodimer IEA Sus scrofa 30616 R-SSC-909729 https://reactome.org/PathwayBrowser/#/R-SSC-909729 Activation of JAK kinases IEA Sus scrofa 30616 R-SSC-909730 https://reactome.org/PathwayBrowser/#/R-SSC-909730 Phosphorylation of INFAR1 by TYK2 IEA Sus scrofa 30616 R-SSC-909732 https://reactome.org/PathwayBrowser/#/R-SSC-909732 Phosphorylation of STAT2 IEA Sus scrofa 30616 R-SSC-912527 https://reactome.org/PathwayBrowser/#/R-SSC-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Sus scrofa 30616 R-SSC-913996 https://reactome.org/PathwayBrowser/#/R-SSC-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Sus scrofa 30616 R-SSC-917693 https://reactome.org/PathwayBrowser/#/R-SSC-917693 ESCRT Disassembly IEA Sus scrofa 30616 R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa 30616 R-SSC-917979 https://reactome.org/PathwayBrowser/#/R-SSC-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa 30616 R-SSC-934559 https://reactome.org/PathwayBrowser/#/R-SSC-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Sus scrofa 30616 R-SSC-936802 https://reactome.org/PathwayBrowser/#/R-SSC-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Sus scrofa 30616 R-SSC-936883 https://reactome.org/PathwayBrowser/#/R-SSC-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Sus scrofa 30616 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 30616 R-SSC-936951 https://reactome.org/PathwayBrowser/#/R-SSC-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Sus scrofa 30616 R-SSC-936991 https://reactome.org/PathwayBrowser/#/R-SSC-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Sus scrofa 30616 R-SSC-937034 https://reactome.org/PathwayBrowser/#/R-SSC-937034 IRAK1 phosphorylates Pellino IEA Sus scrofa 30616 R-SSC-937311 https://reactome.org/PathwayBrowser/#/R-SSC-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Sus scrofa 30616 R-SSC-939763 https://reactome.org/PathwayBrowser/#/R-SSC-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Sus scrofa 30616 R-SSC-947531 https://reactome.org/PathwayBrowser/#/R-SSC-947531 Molybdenum ion transfer onto molybdopterin IEA Sus scrofa 30616 R-SSC-947591 https://reactome.org/PathwayBrowser/#/R-SSC-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Sus scrofa 30616 R-SSC-9603420 https://reactome.org/PathwayBrowser/#/R-SSC-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Sus scrofa 30616 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 30616 R-SSC-9606884 https://reactome.org/PathwayBrowser/#/R-SSC-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Sus scrofa 30616 R-SSC-9610153 https://reactome.org/PathwayBrowser/#/R-SSC-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Sus scrofa 30616 R-SSC-9610156 https://reactome.org/PathwayBrowser/#/R-SSC-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Sus scrofa 30616 R-SSC-9610163 https://reactome.org/PathwayBrowser/#/R-SSC-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Sus scrofa 30616 R-SSC-9612501 https://reactome.org/PathwayBrowser/#/R-SSC-9612501 SGK phosphorylates CREB1 IEA Sus scrofa 30616 R-SSC-9612509 https://reactome.org/PathwayBrowser/#/R-SSC-9612509 SGK phosphorylates SRF IEA Sus scrofa 30616 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa 30616 R-SSC-9619355 https://reactome.org/PathwayBrowser/#/R-SSC-9619355 CaMKK autophosphorylates in the cytosol IEA Sus scrofa 30616 R-SSC-9624800 https://reactome.org/PathwayBrowser/#/R-SSC-9624800 CDK1 phosphorylates LBR IEA Sus scrofa 30616 R-SSC-9626817 https://reactome.org/PathwayBrowser/#/R-SSC-9626817 PKC phosphorylates NCF1 IEA Sus scrofa 30616 R-SSC-9626832 https://reactome.org/PathwayBrowser/#/R-SSC-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Sus scrofa 30616 R-SSC-9626880 https://reactome.org/PathwayBrowser/#/R-SSC-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Sus scrofa 30616 R-SSC-9627056 https://reactome.org/PathwayBrowser/#/R-SSC-9627056 Procaspase 9 forms dimer IEA Sus scrofa 30616 R-SSC-9627089 https://reactome.org/PathwayBrowser/#/R-SSC-9627089 CASP9 is phosphorylated at T412 IEA Sus scrofa 30616 R-SSC-9632858 https://reactome.org/PathwayBrowser/#/R-SSC-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Sus scrofa 30616 R-SSC-9632868 https://reactome.org/PathwayBrowser/#/R-SSC-9632868 CDKN1B is phosphorylated in response to estrogen IEA Sus scrofa 30616 R-SSC-9634702 https://reactome.org/PathwayBrowser/#/R-SSC-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Sus scrofa 30616 R-SSC-9645442 https://reactome.org/PathwayBrowser/#/R-SSC-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Sus scrofa 30616 R-SSC-9645535 https://reactome.org/PathwayBrowser/#/R-SSC-9645535 ALPK1 phosphorylates TIFA IEA Sus scrofa 30616 R-SSC-9648089 https://reactome.org/PathwayBrowser/#/R-SSC-9648089 NEK6 and NEK7 phosphorylate EML4 IEA Sus scrofa 30616 R-SSC-964958 https://reactome.org/PathwayBrowser/#/R-SSC-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Sus scrofa 30616 R-SSC-964962 https://reactome.org/PathwayBrowser/#/R-SSC-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Sus scrofa 30616 R-SSC-964970 https://reactome.org/PathwayBrowser/#/R-SSC-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Sus scrofa 30616 R-SSC-9653503 https://reactome.org/PathwayBrowser/#/R-SSC-9653503 KRAS4B is phosphorylated on serine 181 IEA Sus scrofa 30616 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 30616 R-SSC-9661417 https://reactome.org/PathwayBrowser/#/R-SSC-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa 30616 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 30616 R-SSC-9684118 https://reactome.org/PathwayBrowser/#/R-SSC-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa 30616 R-SSC-9686521 https://reactome.org/PathwayBrowser/#/R-SSC-9686521 CDK2:CCNA phosphorylates TERF2 IEA Sus scrofa 30616 R-SSC-9687625 https://reactome.org/PathwayBrowser/#/R-SSC-9687625 ATP binds MLKL IEA Sus scrofa 30616 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 30616 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 30616 R-SSC-9699578 https://reactome.org/PathwayBrowser/#/R-SSC-9699578 Active FLT3 phosphorylates CDKN1B IEA Sus scrofa 30616 R-SSC-9700168 https://reactome.org/PathwayBrowser/#/R-SSC-9700168 Active ALK phosphorylates IRS1 IEA Sus scrofa 30616 R-SSC-9700171 https://reactome.org/PathwayBrowser/#/R-SSC-9700171 Active ALK phosphorylates PLCG1 IEA Sus scrofa 30616 R-SSC-9700175 https://reactome.org/PathwayBrowser/#/R-SSC-9700175 Active ALK phosphorylates SHC1 IEA Sus scrofa 30616 R-SSC-9701488 https://reactome.org/PathwayBrowser/#/R-SSC-9701488 Active ALK phosphorylates JAK3 IEA Sus scrofa 30616 R-SSC-9705925 https://reactome.org/PathwayBrowser/#/R-SSC-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Sus scrofa 30616 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 30616 R-SSC-9706344 https://reactome.org/PathwayBrowser/#/R-SSC-9706344 FLT3 phosphorylates GRB10 IEA Sus scrofa 30616 R-SSC-9706350 https://reactome.org/PathwayBrowser/#/R-SSC-9706350 FLT3 phosphorylates CBL IEA Sus scrofa 30616 R-SSC-9706837 https://reactome.org/PathwayBrowser/#/R-SSC-9706837 AR binds AR antagonists IEA Sus scrofa 30616 R-SSC-9709547 https://reactome.org/PathwayBrowser/#/R-SSC-9709547 ESTG binds ESR2:chaperone complex IEA Sus scrofa 30616 R-SSC-9716913 https://reactome.org/PathwayBrowser/#/R-SSC-9716913 ESR1 binds ESR1 antagonists IEA Sus scrofa 30616 R-SSC-9716947 https://reactome.org/PathwayBrowser/#/R-SSC-9716947 ESR1 binds ESR1 agonists IEA Sus scrofa 30616 R-SSC-9725855 https://reactome.org/PathwayBrowser/#/R-SSC-9725855 NR3C2 binds NR3C2 antagonists IEA Sus scrofa 30616 R-SSC-9725885 https://reactome.org/PathwayBrowser/#/R-SSC-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Sus scrofa 30616 R-SSC-9726509 https://reactome.org/PathwayBrowser/#/R-SSC-9726509 NR3C2 binds fludrocortisone IEA Sus scrofa 30616 R-SSC-9726580 https://reactome.org/PathwayBrowser/#/R-SSC-9726580 PGR binds PGR agonists IEA Sus scrofa 30616 R-SSC-9726621 https://reactome.org/PathwayBrowser/#/R-SSC-9726621 PGR binds PGR antagonists IEA Sus scrofa 30616 R-SSC-9727198 https://reactome.org/PathwayBrowser/#/R-SSC-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Sus scrofa 30616 R-SSC-9731111 https://reactome.org/PathwayBrowser/#/R-SSC-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Sus scrofa 30616 R-SSC-9732738 https://reactome.org/PathwayBrowser/#/R-SSC-9732738 JAK1-mediated phosphorylation of RAF1 IEA Sus scrofa 30616 R-SSC-9732753 https://reactome.org/PathwayBrowser/#/R-SSC-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Sus scrofa 30616 R-SSC-9734535 https://reactome.org/PathwayBrowser/#/R-SSC-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Sus scrofa 30616 R-SSC-9734547 https://reactome.org/PathwayBrowser/#/R-SSC-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Sus scrofa 30616 R-SSC-9734687 https://reactome.org/PathwayBrowser/#/R-SSC-9734687 ORC6 is phosphorylated on T195 IEA Sus scrofa 30616 R-SSC-9748949 https://reactome.org/PathwayBrowser/#/R-SSC-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Sus scrofa 30616 R-SSC-9748957 https://reactome.org/PathwayBrowser/#/R-SSC-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Sus scrofa 30616 R-SSC-9748963 https://reactome.org/PathwayBrowser/#/R-SSC-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Sus scrofa 30616 R-SSC-9748969 https://reactome.org/PathwayBrowser/#/R-SSC-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Sus scrofa 30616 R-SSC-9748999 https://reactome.org/PathwayBrowser/#/R-SSC-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Sus scrofa 30616 R-SSC-9749971 https://reactome.org/PathwayBrowser/#/R-SSC-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Sus scrofa 30616 R-SSC-9750546 https://reactome.org/PathwayBrowser/#/R-SSC-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-9750656 https://reactome.org/PathwayBrowser/#/R-SSC-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Sus scrofa 30616 R-SSC-975103 https://reactome.org/PathwayBrowser/#/R-SSC-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Sus scrofa 30616 R-SSC-975139 https://reactome.org/PathwayBrowser/#/R-SSC-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Sus scrofa 30616 R-SSC-9753278 https://reactome.org/PathwayBrowser/#/R-SSC-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 30616 R-SSC-9753283 https://reactome.org/PathwayBrowser/#/R-SSC-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 30616 R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 30616 R-SSC-9754974 https://reactome.org/PathwayBrowser/#/R-SSC-9754974 ADK phosphorylates RBV IEA Sus scrofa 30616 R-SSC-9755013 https://reactome.org/PathwayBrowser/#/R-SSC-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Sus scrofa 30616 R-SSC-9759206 https://reactome.org/PathwayBrowser/#/R-SSC-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Sus scrofa 30616 R-SSC-9759454 https://reactome.org/PathwayBrowser/#/R-SSC-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Sus scrofa 30616 R-SSC-9759461 https://reactome.org/PathwayBrowser/#/R-SSC-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Sus scrofa 30616 R-SSC-9760094 https://reactome.org/PathwayBrowser/#/R-SSC-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Sus scrofa 30616 R-SSC-9762094 https://reactome.org/PathwayBrowser/#/R-SSC-9762094 GSK3B phosphorylates p-NFE2L2 IEA Sus scrofa 30616 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa 30616 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa 30616 R-SSC-9773803 https://reactome.org/PathwayBrowser/#/R-SSC-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Sus scrofa 30616 R-SSC-9794120 https://reactome.org/PathwayBrowser/#/R-SSC-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Sus scrofa 30616 R-SSC-9794572 https://reactome.org/PathwayBrowser/#/R-SSC-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Sus scrofa 30616 R-SSC-9796053 https://reactome.org/PathwayBrowser/#/R-SSC-9796053 PRKCI phosphorylates NFE2L2 IEA Sus scrofa 30616 R-SSC-9796067 https://reactome.org/PathwayBrowser/#/R-SSC-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Sus scrofa 30616 R-SSC-9815501 https://reactome.org/PathwayBrowser/#/R-SSC-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 IEA Sus scrofa 30616 R-SSC-9817397 https://reactome.org/PathwayBrowser/#/R-SSC-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Sus scrofa 30616 R-SSC-9818789 https://reactome.org/PathwayBrowser/#/R-SSC-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Sus scrofa 30616 R-SSC-9819106 https://reactome.org/PathwayBrowser/#/R-SSC-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Sus scrofa 30616 R-SSC-9823906 https://reactome.org/PathwayBrowser/#/R-SSC-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Sus scrofa 30616 R-SSC-9824882 https://reactome.org/PathwayBrowser/#/R-SSC-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Sus scrofa 30616 R-SSC-9824977 https://reactome.org/PathwayBrowser/#/R-SSC-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Sus scrofa 30616 R-SSC-9824994 https://reactome.org/PathwayBrowser/#/R-SSC-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Sus scrofa 30616 R-SSC-9824995 https://reactome.org/PathwayBrowser/#/R-SSC-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Sus scrofa 30616 R-SSC-9824999 https://reactome.org/PathwayBrowser/#/R-SSC-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Sus scrofa 30616 R-SSC-9825759 https://reactome.org/PathwayBrowser/#/R-SSC-9825759 MAPK-dependent phosphorylation of KARS IEA Sus scrofa 30616 R-SSC-982810 https://reactome.org/PathwayBrowser/#/R-SSC-982810 JAK2 phosphorylation IEA Sus scrofa 30616 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa 30616 R-SSC-983144 https://reactome.org/PathwayBrowser/#/R-SSC-983144 Transport of Antigen peptide in to ER IEA Sus scrofa 30616 R-SSC-983153 https://reactome.org/PathwayBrowser/#/R-SSC-983153 E1 mediated ubiquitin activation IEA Sus scrofa 30616 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa 30616 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa 30616 R-SSC-9833973 https://reactome.org/PathwayBrowser/#/R-SSC-9833973 ISGylation of PKR IEA Sus scrofa 30616 R-SSC-9836159 https://reactome.org/PathwayBrowser/#/R-SSC-9836159 p-PKR dimer phosphorylates DHX9 IEA Sus scrofa 30616 R-SSC-9836184 https://reactome.org/PathwayBrowser/#/R-SSC-9836184 p-PKR dimer phosphorylates CDK1 IEA Sus scrofa 30616 R-SSC-9836322 https://reactome.org/PathwayBrowser/#/R-SSC-9836322 p-PKR dimer phosphorylates MKK6 IEA Sus scrofa 30616 R-SSC-9836362 https://reactome.org/PathwayBrowser/#/R-SSC-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Sus scrofa 30616 R-SSC-9836383 https://reactome.org/PathwayBrowser/#/R-SSC-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Sus scrofa 30616 R-SSC-9836404 https://reactome.org/PathwayBrowser/#/R-SSC-9836404 p-PKR dimer phosphorylates MAPT IEA Sus scrofa 30616 R-SSC-9836435 https://reactome.org/PathwayBrowser/#/R-SSC-9836435 p-PKR dimer phosphorylates SNCA IEA Sus scrofa 30616 R-SSC-9836515 https://reactome.org/PathwayBrowser/#/R-SSC-9836515 p-PKR dimer phosphorylates PTPN2 IEA Sus scrofa 30616 R-SSC-9836617 https://reactome.org/PathwayBrowser/#/R-SSC-9836617 p-PKR dimer phosphorylates SPHK1 IEA Sus scrofa 30616 R-SSC-9836664 https://reactome.org/PathwayBrowser/#/R-SSC-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Sus scrofa 30616 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa 30616 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa 30616 R-SSC-9837337 https://reactome.org/PathwayBrowser/#/R-SSC-9837337 DCAKD phosphorylates DP-CoA IEA Sus scrofa 30616 R-SSC-9838004 https://reactome.org/PathwayBrowser/#/R-SSC-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Sus scrofa 30616 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa 30616 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa 30616 R-SSC-9838321 https://reactome.org/PathwayBrowser/#/R-SSC-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Sus scrofa 30616 R-SSC-9839059 https://reactome.org/PathwayBrowser/#/R-SSC-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Sus scrofa 30616 R-SSC-9839105 https://reactome.org/PathwayBrowser/#/R-SSC-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Sus scrofa 30616 R-SSC-9839113 https://reactome.org/PathwayBrowser/#/R-SSC-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Sus scrofa 30616 R-SSC-9843721 https://reactome.org/PathwayBrowser/#/R-SSC-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Sus scrofa 30616 R-SSC-9851972 https://reactome.org/PathwayBrowser/#/R-SSC-9851972 PLK1 phosphorylates FIRRM at S43 IEA Sus scrofa 30616 R-SSC-9853369 https://reactome.org/PathwayBrowser/#/R-SSC-9853369 PLK1 phosphorylates FIRMM at S744 IEA Sus scrofa 30616 R-SSC-9861642 https://reactome.org/PathwayBrowser/#/R-SSC-9861642 NEK1 phosphorylates ME1 IEA Sus scrofa 30616 R-SSC-994137 https://reactome.org/PathwayBrowser/#/R-SSC-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Sus scrofa 30616 R-SSC-994140 https://reactome.org/PathwayBrowser/#/R-SSC-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Sus scrofa 30616 R-TAE-2408513 https://reactome.org/PathwayBrowser/#/R-TAE-2408513 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Triticum aestivum 30616 R-VRA-2408510 https://reactome.org/PathwayBrowser/#/R-VRA-2408510 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Vigna radiata var. radiata 30616 R-XLA-2520871 https://reactome.org/PathwayBrowser/#/R-XLA-2520871 Cdk1 phosphorylates condensin I TAS Xenopus laevis 30616 R-XTR-109624 https://reactome.org/PathwayBrowser/#/R-XTR-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Xenopus tropicalis 30616 R-XTR-109671 https://reactome.org/PathwayBrowser/#/R-XTR-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Xenopus tropicalis 30616 R-XTR-109699 https://reactome.org/PathwayBrowser/#/R-XTR-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-109759 https://reactome.org/PathwayBrowser/#/R-XTR-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Xenopus tropicalis 30616 R-XTR-109903 https://reactome.org/PathwayBrowser/#/R-XTR-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Xenopus tropicalis 30616 R-XTR-110133 https://reactome.org/PathwayBrowser/#/R-XTR-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Xenopus tropicalis 30616 R-XTR-110137 https://reactome.org/PathwayBrowser/#/R-XTR-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Xenopus tropicalis 30616 R-XTR-110138 https://reactome.org/PathwayBrowser/#/R-XTR-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 30616 R-XTR-110144 https://reactome.org/PathwayBrowser/#/R-XTR-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Xenopus tropicalis 30616 R-XTR-110145 https://reactome.org/PathwayBrowser/#/R-XTR-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Xenopus tropicalis 30616 R-XTR-1112510 https://reactome.org/PathwayBrowser/#/R-XTR-1112510 IL6ST is tyrosine phosphorylated IEA Xenopus tropicalis 30616 R-XTR-1112514 https://reactome.org/PathwayBrowser/#/R-XTR-1112514 JAK activation IEA Xenopus tropicalis 30616 R-XTR-1112602 https://reactome.org/PathwayBrowser/#/R-XTR-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Xenopus tropicalis 30616 R-XTR-1112703 https://reactome.org/PathwayBrowser/#/R-XTR-1112703 PTPN11 is phosphorylated IEA Xenopus tropicalis 30616 R-XTR-1112727 https://reactome.org/PathwayBrowser/#/R-XTR-1112727 Serine phosphorylation of STATs IEA Xenopus tropicalis 30616 R-XTR-111742 https://reactome.org/PathwayBrowser/#/R-XTR-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 30616 R-XTR-111898 https://reactome.org/PathwayBrowser/#/R-XTR-111898 Phosphorylation of cPLA2 by ERK-2 IEA Xenopus tropicalis 30616 R-XTR-111930 https://reactome.org/PathwayBrowser/#/R-XTR-111930 Adenylate cyclase produces cAMP IEA Xenopus tropicalis 30616 R-XTR-111970 https://reactome.org/PathwayBrowser/#/R-XTR-111970 PKC phosphorylates GRK2 IEA Xenopus tropicalis 30616 R-XTR-112381 https://reactome.org/PathwayBrowser/#/R-XTR-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Xenopus tropicalis 30616 R-XTR-114252 https://reactome.org/PathwayBrowser/#/R-XTR-114252 Cleavage of Procaspase-3 by the apoptosome IEA Xenopus tropicalis 30616 R-XTR-114254 https://reactome.org/PathwayBrowser/#/R-XTR-114254 CYCS binds to APAF1 IEA Xenopus tropicalis 30616 R-XTR-114256 https://reactome.org/PathwayBrowser/#/R-XTR-114256 CYCS:APAF1 binds procaspase-9 IEA Xenopus tropicalis 30616 R-XTR-114261 https://reactome.org/PathwayBrowser/#/R-XTR-114261 Cleavage of Procaspase-7 by the apoptosome IEA Xenopus tropicalis 30616 R-XTR-114600 https://reactome.org/PathwayBrowser/#/R-XTR-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Xenopus tropicalis 30616 R-XTR-114683 https://reactome.org/PathwayBrowser/#/R-XTR-114683 Phosphorylation of Platelet Sec-1 IEA Xenopus tropicalis 30616 R-XTR-114684 https://reactome.org/PathwayBrowser/#/R-XTR-114684 Phosphorylation of Syntaxin-4 IEA Xenopus tropicalis 30616 R-XTR-1168635 https://reactome.org/PathwayBrowser/#/R-XTR-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Xenopus tropicalis 30616 R-XTR-1181149 https://reactome.org/PathwayBrowser/#/R-XTR-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Xenopus tropicalis 30616 R-XTR-1226094 https://reactome.org/PathwayBrowser/#/R-XTR-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Xenopus tropicalis 30616 R-XTR-1226095 https://reactome.org/PathwayBrowser/#/R-XTR-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Xenopus tropicalis 30616 R-XTR-1247935 https://reactome.org/PathwayBrowser/#/R-XTR-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Xenopus tropicalis 30616 R-XTR-1247960 https://reactome.org/PathwayBrowser/#/R-XTR-1247960 Activation of p38 MAPK IEA Xenopus tropicalis 30616 R-XTR-1250195 https://reactome.org/PathwayBrowser/#/R-XTR-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Xenopus tropicalis 30616 R-XTR-1250315 https://reactome.org/PathwayBrowser/#/R-XTR-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Xenopus tropicalis 30616 R-XTR-1250348 https://reactome.org/PathwayBrowser/#/R-XTR-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Xenopus tropicalis 30616 R-XTR-1250370 https://reactome.org/PathwayBrowser/#/R-XTR-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Xenopus tropicalis 30616 R-XTR-1296024 https://reactome.org/PathwayBrowser/#/R-XTR-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Xenopus tropicalis 30616 R-XTR-1306957 https://reactome.org/PathwayBrowser/#/R-XTR-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Xenopus tropicalis 30616 R-XTR-1306979 https://reactome.org/PathwayBrowser/#/R-XTR-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Xenopus tropicalis 30616 R-XTR-1307963 https://reactome.org/PathwayBrowser/#/R-XTR-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Xenopus tropicalis 30616 R-XTR-1362270 https://reactome.org/PathwayBrowser/#/R-XTR-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Xenopus tropicalis 30616 R-XTR-1369065 https://reactome.org/PathwayBrowser/#/R-XTR-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Xenopus tropicalis 30616 R-XTR-1370505 https://reactome.org/PathwayBrowser/#/R-XTR-1370505 PRLR is phosphorylated at Ser-349 IEA Xenopus tropicalis 30616 R-XTR-139855 https://reactome.org/PathwayBrowser/#/R-XTR-139855 P2X1-mediated entry of Ca++ from plasma IEA Xenopus tropicalis 30616 R-XTR-1433418 https://reactome.org/PathwayBrowser/#/R-XTR-1433418 Phosphorylation of JAK2 IEA Xenopus tropicalis 30616 R-XTR-1433454 https://reactome.org/PathwayBrowser/#/R-XTR-1433454 Phosphorylation of GAB2 by SFKs IEA Xenopus tropicalis 30616 R-XTR-1433488 https://reactome.org/PathwayBrowser/#/R-XTR-1433488 Phosphorylation of SHP2 by SFKs IEA Xenopus tropicalis 30616 R-XTR-1433506 https://reactome.org/PathwayBrowser/#/R-XTR-1433506 Phosphorylation of APS IEA Xenopus tropicalis 30616 R-XTR-1433514 https://reactome.org/PathwayBrowser/#/R-XTR-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Xenopus tropicalis 30616 R-XTR-1433542 https://reactome.org/PathwayBrowser/#/R-XTR-1433542 Phosphorylation and activation of VAV1 IEA Xenopus tropicalis 30616 R-XTR-1454916 https://reactome.org/PathwayBrowser/#/R-XTR-1454916 The ABCC family mediates organic anion transport IEA Xenopus tropicalis 30616 R-XTR-1454928 https://reactome.org/PathwayBrowser/#/R-XTR-1454928 ABCG4 may mediate cholesterol efflux IEA Xenopus tropicalis 30616 R-XTR-1467466 https://reactome.org/PathwayBrowser/#/R-XTR-1467466 ABCA4 mediates atRAL transport IEA Xenopus tropicalis 30616 R-XTR-1470009 https://reactome.org/PathwayBrowser/#/R-XTR-1470009 Phosphorylation of STATs IEA Xenopus tropicalis 30616 R-XTR-1472121 https://reactome.org/PathwayBrowser/#/R-XTR-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Xenopus tropicalis 30616 R-XTR-1475422 https://reactome.org/PathwayBrowser/#/R-XTR-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Xenopus tropicalis 30616 R-XTR-1483004 https://reactome.org/PathwayBrowser/#/R-XTR-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Xenopus tropicalis 30616 R-XTR-1483222 https://reactome.org/PathwayBrowser/#/R-XTR-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Xenopus tropicalis 30616 R-XTR-1497853 https://reactome.org/PathwayBrowser/#/R-XTR-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Xenopus tropicalis 30616 R-XTR-1524186 https://reactome.org/PathwayBrowser/#/R-XTR-1524186 Phosphorylation of PLCgamma by PDGFR IEA Xenopus tropicalis 30616 R-XTR-1549526 https://reactome.org/PathwayBrowser/#/R-XTR-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Xenopus tropicalis 30616 R-XTR-156673 https://reactome.org/PathwayBrowser/#/R-XTR-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Xenopus tropicalis 30616 R-XTR-156682 https://reactome.org/PathwayBrowser/#/R-XTR-156682 PLK1 phosphorylates NUDC IEA Xenopus tropicalis 30616 R-XTR-156699 https://reactome.org/PathwayBrowser/#/R-XTR-156699 Inactivation of Wee1 kinase IEA Xenopus tropicalis 30616 R-XTR-156723 https://reactome.org/PathwayBrowser/#/R-XTR-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Xenopus tropicalis 30616 R-XTR-159425 https://reactome.org/PathwayBrowser/#/R-XTR-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 30616 R-XTR-159443 https://reactome.org/PathwayBrowser/#/R-XTR-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 30616 R-XTR-159567 https://reactome.org/PathwayBrowser/#/R-XTR-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Xenopus tropicalis 30616 R-XTR-163010 https://reactome.org/PathwayBrowser/#/R-XTR-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Xenopus tropicalis 30616 R-XTR-163215 https://reactome.org/PathwayBrowser/#/R-XTR-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Xenopus tropicalis 30616 R-XTR-1632857 https://reactome.org/PathwayBrowser/#/R-XTR-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Xenopus tropicalis 30616 R-XTR-1638803 https://reactome.org/PathwayBrowser/#/R-XTR-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Xenopus tropicalis 30616 R-XTR-1638845 https://reactome.org/PathwayBrowser/#/R-XTR-1638845 CERK phosphorylates CERA to form C1P IEA Xenopus tropicalis 30616 R-XTR-1675773 https://reactome.org/PathwayBrowser/#/R-XTR-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Xenopus tropicalis 30616 R-XTR-1675776 https://reactome.org/PathwayBrowser/#/R-XTR-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Xenopus tropicalis 30616 R-XTR-1675780 https://reactome.org/PathwayBrowser/#/R-XTR-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Xenopus tropicalis 30616 R-XTR-1675813 https://reactome.org/PathwayBrowser/#/R-XTR-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Xenopus tropicalis 30616 R-XTR-1675883 https://reactome.org/PathwayBrowser/#/R-XTR-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Xenopus tropicalis 30616 R-XTR-1675928 https://reactome.org/PathwayBrowser/#/R-XTR-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Xenopus tropicalis 30616 R-XTR-1675939 https://reactome.org/PathwayBrowser/#/R-XTR-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Xenopus tropicalis 30616 R-XTR-1675961 https://reactome.org/PathwayBrowser/#/R-XTR-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Xenopus tropicalis 30616 R-XTR-1675974 https://reactome.org/PathwayBrowser/#/R-XTR-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Xenopus tropicalis 30616 R-XTR-1676024 https://reactome.org/PathwayBrowser/#/R-XTR-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Xenopus tropicalis 30616 R-XTR-1676048 https://reactome.org/PathwayBrowser/#/R-XTR-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Xenopus tropicalis 30616 R-XTR-1676082 https://reactome.org/PathwayBrowser/#/R-XTR-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Xenopus tropicalis 30616 R-XTR-1676109 https://reactome.org/PathwayBrowser/#/R-XTR-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Xenopus tropicalis 30616 R-XTR-1676145 https://reactome.org/PathwayBrowser/#/R-XTR-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Xenopus tropicalis 30616 R-XTR-1676185 https://reactome.org/PathwayBrowser/#/R-XTR-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Xenopus tropicalis 30616 R-XTR-1676206 https://reactome.org/PathwayBrowser/#/R-XTR-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Xenopus tropicalis 30616 R-XTR-168053 https://reactome.org/PathwayBrowser/#/R-XTR-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Xenopus tropicalis 30616 R-XTR-169905 https://reactome.org/PathwayBrowser/#/R-XTR-169905 ARMS is phosphorylated by active TrkA receptor IEA Xenopus tropicalis 30616 R-XTR-170026 https://reactome.org/PathwayBrowser/#/R-XTR-170026 Protons are translocated from the intermembrane space to the matrix IEA Xenopus tropicalis 30616 R-XTR-170070 https://reactome.org/PathwayBrowser/#/R-XTR-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Xenopus tropicalis 30616 R-XTR-170076 https://reactome.org/PathwayBrowser/#/R-XTR-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Xenopus tropicalis 30616 R-XTR-170087 https://reactome.org/PathwayBrowser/#/R-XTR-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Xenopus tropicalis 30616 R-XTR-170126 https://reactome.org/PathwayBrowser/#/R-XTR-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Xenopus tropicalis 30616 R-XTR-170676 https://reactome.org/PathwayBrowser/#/R-XTR-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Xenopus tropicalis 30616 R-XTR-170977 https://reactome.org/PathwayBrowser/#/R-XTR-170977 FRS2 is phosphorylated by active TrkA receptor IEA Xenopus tropicalis 30616 R-XTR-174079 https://reactome.org/PathwayBrowser/#/R-XTR-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Xenopus tropicalis 30616 R-XTR-174122 https://reactome.org/PathwayBrowser/#/R-XTR-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Xenopus tropicalis 30616 R-XTR-174164 https://reactome.org/PathwayBrowser/#/R-XTR-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Xenopus tropicalis 30616 R-XTR-174174 https://reactome.org/PathwayBrowser/#/R-XTR-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Xenopus tropicalis 30616 R-XTR-174251 https://reactome.org/PathwayBrowser/#/R-XTR-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Xenopus tropicalis 30616 R-XTR-174367 https://reactome.org/PathwayBrowser/#/R-XTR-174367 GCL ligates L-Glu to L-Cys IEA Xenopus tropicalis 30616 R-XTR-174389 https://reactome.org/PathwayBrowser/#/R-XTR-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Xenopus tropicalis 30616 R-XTR-174391 https://reactome.org/PathwayBrowser/#/R-XTR-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Xenopus tropicalis 30616 R-XTR-174392 https://reactome.org/PathwayBrowser/#/R-XTR-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Xenopus tropicalis 30616 R-XTR-174439 https://reactome.org/PathwayBrowser/#/R-XTR-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Xenopus tropicalis 30616 R-XTR-177157 https://reactome.org/PathwayBrowser/#/R-XTR-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 30616 R-XTR-177275 https://reactome.org/PathwayBrowser/#/R-XTR-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Xenopus tropicalis 30616 R-XTR-177284 https://reactome.org/PathwayBrowser/#/R-XTR-177284 PKA phosphorylates PDE4B IEA Xenopus tropicalis 30616 R-XTR-177930 https://reactome.org/PathwayBrowser/#/R-XTR-177930 GAB1 phosphorylation by EGFR kinase IEA Xenopus tropicalis 30616 R-XTR-177933 https://reactome.org/PathwayBrowser/#/R-XTR-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Xenopus tropicalis 30616 R-XTR-177934 https://reactome.org/PathwayBrowser/#/R-XTR-177934 EGFR autophosphorylation IEA Xenopus tropicalis 30616 R-XTR-177939 https://reactome.org/PathwayBrowser/#/R-XTR-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Xenopus tropicalis 30616 R-XTR-183058 https://reactome.org/PathwayBrowser/#/R-XTR-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Xenopus tropicalis 30616 R-XTR-1855157 https://reactome.org/PathwayBrowser/#/R-XTR-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 30616 R-XTR-1855158 https://reactome.org/PathwayBrowser/#/R-XTR-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855162 https://reactome.org/PathwayBrowser/#/R-XTR-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855169 https://reactome.org/PathwayBrowser/#/R-XTR-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855172 https://reactome.org/PathwayBrowser/#/R-XTR-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855176 https://reactome.org/PathwayBrowser/#/R-XTR-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Xenopus tropicalis 30616 R-XTR-1855179 https://reactome.org/PathwayBrowser/#/R-XTR-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855181 https://reactome.org/PathwayBrowser/#/R-XTR-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 30616 R-XTR-1855182 https://reactome.org/PathwayBrowser/#/R-XTR-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855185 https://reactome.org/PathwayBrowser/#/R-XTR-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 30616 R-XTR-1855193 https://reactome.org/PathwayBrowser/#/R-XTR-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855194 https://reactome.org/PathwayBrowser/#/R-XTR-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855197 https://reactome.org/PathwayBrowser/#/R-XTR-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855206 https://reactome.org/PathwayBrowser/#/R-XTR-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 30616 R-XTR-1855207 https://reactome.org/PathwayBrowser/#/R-XTR-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 30616 R-XTR-1855216 https://reactome.org/PathwayBrowser/#/R-XTR-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855223 https://reactome.org/PathwayBrowser/#/R-XTR-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855224 https://reactome.org/PathwayBrowser/#/R-XTR-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 30616 R-XTR-1855227 https://reactome.org/PathwayBrowser/#/R-XTR-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 30616 R-XTR-1855228 https://reactome.org/PathwayBrowser/#/R-XTR-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 30616 R-XTR-1855230 https://reactome.org/PathwayBrowser/#/R-XTR-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 30616 R-XTR-1855233 https://reactome.org/PathwayBrowser/#/R-XTR-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Xenopus tropicalis 30616 R-XTR-186786 https://reactome.org/PathwayBrowser/#/R-XTR-186786 Autophosphorylation of PDGF beta receptors IEA Xenopus tropicalis 30616 R-XTR-186800 https://reactome.org/PathwayBrowser/#/R-XTR-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-187520 https://reactome.org/PathwayBrowser/#/R-XTR-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Xenopus tropicalis 30616 R-XTR-187916 https://reactome.org/PathwayBrowser/#/R-XTR-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Xenopus tropicalis 30616 R-XTR-187948 https://reactome.org/PathwayBrowser/#/R-XTR-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Xenopus tropicalis 30616 R-XTR-187949 https://reactome.org/PathwayBrowser/#/R-XTR-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Xenopus tropicalis 30616 R-XTR-187959 https://reactome.org/PathwayBrowser/#/R-XTR-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Xenopus tropicalis 30616 R-XTR-188350 https://reactome.org/PathwayBrowser/#/R-XTR-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Xenopus tropicalis 30616 R-XTR-188390 https://reactome.org/PathwayBrowser/#/R-XTR-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Xenopus tropicalis 30616 R-XTR-190326 https://reactome.org/PathwayBrowser/#/R-XTR-190326 Autocatalytic phosphorylation of FGFR4 IEA Xenopus tropicalis 30616 R-XTR-190427 https://reactome.org/PathwayBrowser/#/R-XTR-190427 Autocatalytic phosphorylation of FGFR1b IEA Xenopus tropicalis 30616 R-XTR-190429 https://reactome.org/PathwayBrowser/#/R-XTR-190429 Autocatalytic phosphorylation of FGFR1c IEA Xenopus tropicalis 30616 R-XTR-191062 https://reactome.org/PathwayBrowser/#/R-XTR-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Xenopus tropicalis 30616 R-XTR-191414 https://reactome.org/PathwayBrowser/#/R-XTR-191414 MVD decarboxylates MVA5PP to IPPP IEA Xenopus tropicalis 30616 R-XTR-192137 https://reactome.org/PathwayBrowser/#/R-XTR-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 30616 R-XTR-193401 https://reactome.org/PathwayBrowser/#/R-XTR-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 30616 R-XTR-193407 https://reactome.org/PathwayBrowser/#/R-XTR-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 30616 R-XTR-193424 https://reactome.org/PathwayBrowser/#/R-XTR-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 30616 R-XTR-193711 https://reactome.org/PathwayBrowser/#/R-XTR-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 30616 R-XTR-193727 https://reactome.org/PathwayBrowser/#/R-XTR-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 30616 R-XTR-193743 https://reactome.org/PathwayBrowser/#/R-XTR-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 30616 R-XTR-193766 https://reactome.org/PathwayBrowser/#/R-XTR-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 30616 R-XTR-194153 https://reactome.org/PathwayBrowser/#/R-XTR-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 30616 R-XTR-196753 https://reactome.org/PathwayBrowser/#/R-XTR-196753 2xPPCS ligates PPanK with Cys IEA Xenopus tropicalis 30616 R-XTR-196754 https://reactome.org/PathwayBrowser/#/R-XTR-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Xenopus tropicalis 30616 R-XTR-196761 https://reactome.org/PathwayBrowser/#/R-XTR-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Xenopus tropicalis 30616 R-XTR-196773 https://reactome.org/PathwayBrowser/#/R-XTR-196773 COASY phosphorylates DP-CoA IEA Xenopus tropicalis 30616 R-XTR-196857 https://reactome.org/PathwayBrowser/#/R-XTR-196857 PANK2 phosphorylates PanK IEA Xenopus tropicalis 30616 R-XTR-196964 https://reactome.org/PathwayBrowser/#/R-XTR-196964 RFK:Mg2+ phosphorylates RIB IEA Xenopus tropicalis 30616 R-XTR-197198 https://reactome.org/PathwayBrowser/#/R-XTR-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 30616 R-XTR-197958 https://reactome.org/PathwayBrowser/#/R-XTR-197958 FPGS-2 transforms THF to THFPG IEA Xenopus tropicalis 30616 R-XTR-198266 https://reactome.org/PathwayBrowser/#/R-XTR-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Xenopus tropicalis 30616 R-XTR-198314 https://reactome.org/PathwayBrowser/#/R-XTR-198314 DAG stimulates protein kinase C-delta IEA Xenopus tropicalis 30616 R-XTR-198746 https://reactome.org/PathwayBrowser/#/R-XTR-198746 ERK1/2/5 activate RSK1/2/3 IEA Xenopus tropicalis 30616 R-XTR-199895 https://reactome.org/PathwayBrowser/#/R-XTR-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Xenopus tropicalis 30616 R-XTR-200318 https://reactome.org/PathwayBrowser/#/R-XTR-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Xenopus tropicalis 30616 R-XTR-200326 https://reactome.org/PathwayBrowser/#/R-XTR-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Xenopus tropicalis 30616 R-XTR-200555 https://reactome.org/PathwayBrowser/#/R-XTR-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Xenopus tropicalis 30616 R-XTR-200681 https://reactome.org/PathwayBrowser/#/R-XTR-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Xenopus tropicalis 30616 R-XTR-200682 https://reactome.org/PathwayBrowser/#/R-XTR-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Xenopus tropicalis 30616 R-XTR-200711 https://reactome.org/PathwayBrowser/#/R-XTR-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Xenopus tropicalis 30616 R-XTR-201035 https://reactome.org/PathwayBrowser/#/R-XTR-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Xenopus tropicalis 30616 R-XTR-201443 https://reactome.org/PathwayBrowser/#/R-XTR-201443 Type II receptor phosphorylates type I receptor IEA Xenopus tropicalis 30616 R-XTR-201476 https://reactome.org/PathwayBrowser/#/R-XTR-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Xenopus tropicalis 30616 R-XTR-201510 https://reactome.org/PathwayBrowser/#/R-XTR-201510 PI3K synthesizes PIP3 downstream of ALK IEA Xenopus tropicalis 30616 R-XTR-202248 https://reactome.org/PathwayBrowser/#/R-XTR-202248 Phosphorylation of PLC-gamma1 IEA Xenopus tropicalis 30616 R-XTR-2028284 https://reactome.org/PathwayBrowser/#/R-XTR-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Xenopus tropicalis 30616 R-XTR-2028555 https://reactome.org/PathwayBrowser/#/R-XTR-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Xenopus tropicalis 30616 R-XTR-2028589 https://reactome.org/PathwayBrowser/#/R-XTR-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Xenopus tropicalis 30616 R-XTR-2028591 https://reactome.org/PathwayBrowser/#/R-XTR-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Xenopus tropicalis 30616 R-XTR-2028598 https://reactome.org/PathwayBrowser/#/R-XTR-2028598 Phosphorylation of YAP by LATS1 IEA Xenopus tropicalis 30616 R-XTR-2028629 https://reactome.org/PathwayBrowser/#/R-XTR-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Xenopus tropicalis 30616 R-XTR-2028635 https://reactome.org/PathwayBrowser/#/R-XTR-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Xenopus tropicalis 30616 R-XTR-2028670 https://reactome.org/PathwayBrowser/#/R-XTR-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Xenopus tropicalis 30616 R-XTR-2028673 https://reactome.org/PathwayBrowser/#/R-XTR-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Xenopus tropicalis 30616 R-XTR-2028675 https://reactome.org/PathwayBrowser/#/R-XTR-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Xenopus tropicalis 30616 R-XTR-2028679 https://reactome.org/PathwayBrowser/#/R-XTR-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Xenopus tropicalis 30616 R-XTR-2029454 https://reactome.org/PathwayBrowser/#/R-XTR-2029454 Autophosphorylation of PAK1 IEA Xenopus tropicalis 30616 R-XTR-2029460 https://reactome.org/PathwayBrowser/#/R-XTR-2029460 PAK1 phosphorylates LIMK1 IEA Xenopus tropicalis 30616 R-XTR-2029466 https://reactome.org/PathwayBrowser/#/R-XTR-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Xenopus tropicalis 30616 R-XTR-2029469 https://reactome.org/PathwayBrowser/#/R-XTR-2029469 p-ERK phosphorylates WAVEs and ABI IEA Xenopus tropicalis 30616 R-XTR-2029473 https://reactome.org/PathwayBrowser/#/R-XTR-2029473 Branching and elongation of mother and daughter filaments IEA Xenopus tropicalis 30616 R-XTR-203070 https://reactome.org/PathwayBrowser/#/R-XTR-203070 Association of profilin with monomeric actin IEA Xenopus tropicalis 30616 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 30616 R-XTR-2046085 https://reactome.org/PathwayBrowser/#/R-XTR-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Xenopus tropicalis 30616 R-XTR-2046087 https://reactome.org/PathwayBrowser/#/R-XTR-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Xenopus tropicalis 30616 R-XTR-2046093 https://reactome.org/PathwayBrowser/#/R-XTR-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Xenopus tropicalis 30616 R-XTR-2046098 https://reactome.org/PathwayBrowser/#/R-XTR-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Xenopus tropicalis 30616 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 30616 R-XTR-2060328 https://reactome.org/PathwayBrowser/#/R-XTR-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Xenopus tropicalis 30616 R-XTR-212710 https://reactome.org/PathwayBrowser/#/R-XTR-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Xenopus tropicalis 30616 R-XTR-2130194 https://reactome.org/PathwayBrowser/#/R-XTR-2130194 ABL phosphorylates WAVEs IEA Xenopus tropicalis 30616 R-XTR-2197690 https://reactome.org/PathwayBrowser/#/R-XTR-2197690 Detachment of WASP/WAVE IEA Xenopus tropicalis 30616 R-XTR-2214351 https://reactome.org/PathwayBrowser/#/R-XTR-2214351 PLK1 phosphorylates GORASP1 IEA Xenopus tropicalis 30616 R-XTR-2267372 https://reactome.org/PathwayBrowser/#/R-XTR-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Xenopus tropicalis 30616 R-XTR-2316434 https://reactome.org/PathwayBrowser/#/R-XTR-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-2404193 https://reactome.org/PathwayBrowser/#/R-XTR-2404193 IGF1R phosphorylates SHC1 IEA Xenopus tropicalis 30616 R-XTR-2404199 https://reactome.org/PathwayBrowser/#/R-XTR-2404199 IGF1,2:IGF1R autophosphorylates IEA Xenopus tropicalis 30616 R-XTR-2408551 https://reactome.org/PathwayBrowser/#/R-XTR-2408551 SeMet is converted to AdoSeMet by MAT IEA Xenopus tropicalis 30616 R-XTR-2422927 https://reactome.org/PathwayBrowser/#/R-XTR-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Xenopus tropicalis 30616 R-XTR-2424487 https://reactome.org/PathwayBrowser/#/R-XTR-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Xenopus tropicalis 30616 R-XTR-2428926 https://reactome.org/PathwayBrowser/#/R-XTR-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Xenopus tropicalis 30616 R-XTR-2466068 https://reactome.org/PathwayBrowser/#/R-XTR-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Xenopus tropicalis 30616 R-XTR-2468287 https://reactome.org/PathwayBrowser/#/R-XTR-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Xenopus tropicalis 30616 R-XTR-2468293 https://reactome.org/PathwayBrowser/#/R-XTR-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Xenopus tropicalis 30616 R-XTR-2562526 https://reactome.org/PathwayBrowser/#/R-XTR-2562526 PLK1 phosphorylates OPTN IEA Xenopus tropicalis 30616 R-XTR-2574840 https://reactome.org/PathwayBrowser/#/R-XTR-2574840 AJUBA facilitates AURKA autophosphorylation IEA Xenopus tropicalis 30616 R-XTR-265682 https://reactome.org/PathwayBrowser/#/R-XTR-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Xenopus tropicalis 30616 R-XTR-266082 https://reactome.org/PathwayBrowser/#/R-XTR-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Xenopus tropicalis 30616 R-XTR-2730841 https://reactome.org/PathwayBrowser/#/R-XTR-2730841 Phosphorylation and activation of VAV IEA Xenopus tropicalis 30616 R-XTR-2730856 https://reactome.org/PathwayBrowser/#/R-XTR-2730856 Autophosphorylation of PAK IEA Xenopus tropicalis 30616 R-XTR-2730858 https://reactome.org/PathwayBrowser/#/R-XTR-2730858 Autophosphorylation of BTK/ITK IEA Xenopus tropicalis 30616 R-XTR-2730862 https://reactome.org/PathwayBrowser/#/R-XTR-2730862 Autophosphorylation of LYN kinase IEA Xenopus tropicalis 30616 R-XTR-2730870 https://reactome.org/PathwayBrowser/#/R-XTR-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Xenopus tropicalis 30616 R-XTR-2730896 https://reactome.org/PathwayBrowser/#/R-XTR-2730896 Phosphorylation of MEK4 by MEKK1 IEA Xenopus tropicalis 30616 R-XTR-2990833 https://reactome.org/PathwayBrowser/#/R-XTR-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Xenopus tropicalis 30616 R-XTR-2990882 https://reactome.org/PathwayBrowser/#/R-XTR-2990882 CDK1 phosphorylates NUP98 IEA Xenopus tropicalis 30616 R-XTR-2993447 https://reactome.org/PathwayBrowser/#/R-XTR-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Xenopus tropicalis 30616 R-XTR-2993799 https://reactome.org/PathwayBrowser/#/R-XTR-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Xenopus tropicalis 30616 R-XTR-2993802 https://reactome.org/PathwayBrowser/#/R-XTR-2993802 HLCS biotinylates PC:Mn2+ IEA Xenopus tropicalis 30616 R-XTR-2993814 https://reactome.org/PathwayBrowser/#/R-XTR-2993814 HLCS biotinylates ACACA:Mn2+ IEA Xenopus tropicalis 30616 R-XTR-3000310 https://reactome.org/PathwayBrowser/#/R-XTR-3000310 AURKA phosphorylates PLK1 IEA Xenopus tropicalis 30616 R-XTR-3000327 https://reactome.org/PathwayBrowser/#/R-XTR-3000327 PLK1 phosphorylates BORA IEA Xenopus tropicalis 30616 R-XTR-3095901 https://reactome.org/PathwayBrowser/#/R-XTR-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Xenopus tropicalis 30616 R-XTR-3132737 https://reactome.org/PathwayBrowser/#/R-XTR-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Xenopus tropicalis 30616 R-XTR-3159253 https://reactome.org/PathwayBrowser/#/R-XTR-3159253 MMAB adenosylates cob(I)alamin IEA Xenopus tropicalis 30616 R-XTR-3249371 https://reactome.org/PathwayBrowser/#/R-XTR-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Xenopus tropicalis 30616 R-XTR-3249379 https://reactome.org/PathwayBrowser/#/R-XTR-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Xenopus tropicalis 30616 R-XTR-3249390 https://reactome.org/PathwayBrowser/#/R-XTR-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Xenopus tropicalis 30616 R-XTR-3371422 https://reactome.org/PathwayBrowser/#/R-XTR-3371422 ATP hydrolysis by HSP70 IEA Xenopus tropicalis 30616 R-XTR-3371590 https://reactome.org/PathwayBrowser/#/R-XTR-3371590 HSP70 binds to HSP40:nascent protein IEA Xenopus tropicalis 30616 R-XTR-374701 https://reactome.org/PathwayBrowser/#/R-XTR-374701 Phosphorylation of DCC by Fyn IEA Xenopus tropicalis 30616 R-XTR-3772435 https://reactome.org/PathwayBrowser/#/R-XTR-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Xenopus tropicalis 30616 R-XTR-3788705 https://reactome.org/PathwayBrowser/#/R-XTR-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Xenopus tropicalis 30616 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 30616 R-XTR-380272 https://reactome.org/PathwayBrowser/#/R-XTR-380272 Plk1-mediated phosphorylation of Nlp IEA Xenopus tropicalis 30616 R-XTR-380278 https://reactome.org/PathwayBrowser/#/R-XTR-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Xenopus tropicalis 30616 R-XTR-381091 https://reactome.org/PathwayBrowser/#/R-XTR-381091 IRE1 dimer autophosphorylates IEA Xenopus tropicalis 30616 R-XTR-381111 https://reactome.org/PathwayBrowser/#/R-XTR-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Xenopus tropicalis 30616 R-XTR-382560 https://reactome.org/PathwayBrowser/#/R-XTR-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Xenopus tropicalis 30616 R-XTR-382575 https://reactome.org/PathwayBrowser/#/R-XTR-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Xenopus tropicalis 30616 R-XTR-383190 https://reactome.org/PathwayBrowser/#/R-XTR-383190 HCO3- transport through ion channel IEA Xenopus tropicalis 30616 R-XTR-388831 https://reactome.org/PathwayBrowser/#/R-XTR-388831 Phosphorylation of CD28 IEA Xenopus tropicalis 30616 R-XTR-389086 https://reactome.org/PathwayBrowser/#/R-XTR-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Xenopus tropicalis 30616 R-XTR-389158 https://reactome.org/PathwayBrowser/#/R-XTR-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-389354 https://reactome.org/PathwayBrowser/#/R-XTR-389354 Activation of Vav1 IEA Xenopus tropicalis 30616 R-XTR-389622 https://reactome.org/PathwayBrowser/#/R-XTR-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 30616 R-XTR-389632 https://reactome.org/PathwayBrowser/#/R-XTR-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 30616 R-XTR-392300 https://reactome.org/PathwayBrowser/#/R-XTR-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-392530 https://reactome.org/PathwayBrowser/#/R-XTR-392530 p-S400-Cot phosphorylates NIK IEA Xenopus tropicalis 30616 R-XTR-3928578 https://reactome.org/PathwayBrowser/#/R-XTR-3928578 EPH receptors autophosphorylate IEA Xenopus tropicalis 30616 R-XTR-3928604 https://reactome.org/PathwayBrowser/#/R-XTR-3928604 SFKs phosphorylate VAV2,3 IEA Xenopus tropicalis 30616 R-XTR-3928620 https://reactome.org/PathwayBrowser/#/R-XTR-3928620 PAK1 autophosphorylates IEA Xenopus tropicalis 30616 R-XTR-3928625 https://reactome.org/PathwayBrowser/#/R-XTR-3928625 PAKs autophosphorylate IEA Xenopus tropicalis 30616 R-XTR-3928627 https://reactome.org/PathwayBrowser/#/R-XTR-3928627 EPHB phosphorylates TIAM1 IEA Xenopus tropicalis 30616 R-XTR-3928640 https://reactome.org/PathwayBrowser/#/R-XTR-3928640 PAKs phosphorylate MLC IEA Xenopus tropicalis 30616 R-XTR-399939 https://reactome.org/PathwayBrowser/#/R-XTR-399939 Autophosphorylation of PAK IEA Xenopus tropicalis 30616 R-XTR-399944 https://reactome.org/PathwayBrowser/#/R-XTR-399944 Phosphorylation of CRMPs by Cdk5 IEA Xenopus tropicalis 30616 R-XTR-399947 https://reactome.org/PathwayBrowser/#/R-XTR-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Xenopus tropicalis 30616 R-XTR-399952 https://reactome.org/PathwayBrowser/#/R-XTR-399952 Phosphorylation of LIMK-1 by PAK IEA Xenopus tropicalis 30616 R-XTR-4085028 https://reactome.org/PathwayBrowser/#/R-XTR-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Xenopus tropicalis 30616 R-XTR-4086410 https://reactome.org/PathwayBrowser/#/R-XTR-4086410 CDK1 phosphorylates BORA IEA Xenopus tropicalis 30616 R-XTR-4088024 https://reactome.org/PathwayBrowser/#/R-XTR-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Xenopus tropicalis 30616 R-XTR-4088134 https://reactome.org/PathwayBrowser/#/R-XTR-4088134 PLK1 phosphorylates FOXM1 IEA Xenopus tropicalis 30616 R-XTR-4093332 https://reactome.org/PathwayBrowser/#/R-XTR-4093332 p-EPHB phosphorylates SDC2 IEA Xenopus tropicalis 30616 R-XTR-4167511 https://reactome.org/PathwayBrowser/#/R-XTR-4167511 HLCS biotinylates ACACB IEA Xenopus tropicalis 30616 R-XTR-417825 https://reactome.org/PathwayBrowser/#/R-XTR-417825 P2Y11 receptor can bind to ATP IEA Xenopus tropicalis 30616 R-XTR-417927 https://reactome.org/PathwayBrowser/#/R-XTR-417927 P2Y2 receptor binds ATP and UTP IEA Xenopus tropicalis 30616 R-XTR-419490 https://reactome.org/PathwayBrowser/#/R-XTR-419490 Binding of ATP to P2X receptors IEA Xenopus tropicalis 30616 R-XTR-419644 https://reactome.org/PathwayBrowser/#/R-XTR-419644 Transphosphorylation of pLIMK1 IEA Xenopus tropicalis 30616 R-XTR-419646 https://reactome.org/PathwayBrowser/#/R-XTR-419646 SEMA4D interacts with Plexin-B1:Met IEA Xenopus tropicalis 30616 R-XTR-426240 https://reactome.org/PathwayBrowser/#/R-XTR-426240 DAG kinase produces phosphatidic acid from DAG IEA Xenopus tropicalis 30616 R-XTR-428941 https://reactome.org/PathwayBrowser/#/R-XTR-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Xenopus tropicalis 30616 R-XTR-428961 https://reactome.org/PathwayBrowser/#/R-XTR-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Xenopus tropicalis 30616 R-XTR-429449 https://reactome.org/PathwayBrowser/#/R-XTR-429449 Syk activation leads to SLP-76 activation IEA Xenopus tropicalis 30616 R-XTR-430347 https://reactome.org/PathwayBrowser/#/R-XTR-430347 MigFilin associates with Filamin and F-actin IEA Xenopus tropicalis 30616 R-XTR-432148 https://reactome.org/PathwayBrowser/#/R-XTR-432148 Fgr may phosphorylate p38 MAPK IEA Xenopus tropicalis 30616 R-XTR-432232 https://reactome.org/PathwayBrowser/#/R-XTR-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Xenopus tropicalis 30616 R-XTR-434382 https://reactome.org/PathwayBrowser/#/R-XTR-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Xenopus tropicalis 30616 R-XTR-437162 https://reactome.org/PathwayBrowser/#/R-XTR-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-4411402 https://reactome.org/PathwayBrowser/#/R-XTR-4411402 Activation of NLK IEA Xenopus tropicalis 30616 R-XTR-4420117 https://reactome.org/PathwayBrowser/#/R-XTR-4420117 VEGFR2 autophosphorylates IEA Xenopus tropicalis 30616 R-XTR-442724 https://reactome.org/PathwayBrowser/#/R-XTR-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Xenopus tropicalis 30616 R-XTR-443779 https://reactome.org/PathwayBrowser/#/R-XTR-443779 Linkage of L1 with treadmilling F-actin IEA Xenopus tropicalis 30616 R-XTR-445072 https://reactome.org/PathwayBrowser/#/R-XTR-445072 Interaction of PAK1 with Rac1-GTP IEA Xenopus tropicalis 30616 R-XTR-445079 https://reactome.org/PathwayBrowser/#/R-XTR-445079 Phosphorylation of L1 by ERK IEA Xenopus tropicalis 30616 R-XTR-446634 https://reactome.org/PathwayBrowser/#/R-XTR-446634 IRAK4 is activated by autophosphorylation IEA Xenopus tropicalis 30616 R-XTR-448955 https://reactome.org/PathwayBrowser/#/R-XTR-448955 Phosphorylation of MEF2 proteins by p38 IEA Xenopus tropicalis 30616 R-XTR-449911 https://reactome.org/PathwayBrowser/#/R-XTR-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Xenopus tropicalis 30616 R-XTR-450088 https://reactome.org/PathwayBrowser/#/R-XTR-450088 GLUT1 tetramer binds 4xATP IEA Xenopus tropicalis 30616 R-XTR-450092 https://reactome.org/PathwayBrowser/#/R-XTR-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Xenopus tropicalis 30616 R-XTR-450325 https://reactome.org/PathwayBrowser/#/R-XTR-450325 c-FOS activation by phospho ERK1/2 IEA Xenopus tropicalis 30616 R-XTR-450337 https://reactome.org/PathwayBrowser/#/R-XTR-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Xenopus tropicalis 30616 R-XTR-450346 https://reactome.org/PathwayBrowser/#/R-XTR-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Xenopus tropicalis 30616 R-XTR-450533 https://reactome.org/PathwayBrowser/#/R-XTR-450533 PKCdelta phosphorylates HuR IEA Xenopus tropicalis 30616 R-XTR-453200 https://reactome.org/PathwayBrowser/#/R-XTR-453200 SYK autophosphorylates IEA Xenopus tropicalis 30616 R-XTR-453342 https://reactome.org/PathwayBrowser/#/R-XTR-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Xenopus tropicalis 30616 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 30616 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 30616 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 30616 R-XTR-508040 https://reactome.org/PathwayBrowser/#/R-XTR-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Xenopus tropicalis 30616 R-XTR-508308 https://reactome.org/PathwayBrowser/#/R-XTR-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Xenopus tropicalis 30616 R-XTR-5138432 https://reactome.org/PathwayBrowser/#/R-XTR-5138432 DVL2 is phosphorylated by PKC IEA Xenopus tropicalis 30616 R-XTR-5195402 https://reactome.org/PathwayBrowser/#/R-XTR-5195402 CDK1 phosphorylates LPIN IEA Xenopus tropicalis 30616 R-XTR-5218642 https://reactome.org/PathwayBrowser/#/R-XTR-5218642 PTK2 autophosphorylates IEA Xenopus tropicalis 30616 R-XTR-5218804 https://reactome.org/PathwayBrowser/#/R-XTR-5218804 p38 MAPK activation by VEGFR IEA Xenopus tropicalis 30616 R-XTR-5218805 https://reactome.org/PathwayBrowser/#/R-XTR-5218805 PKC autophosphorylates IEA Xenopus tropicalis 30616 R-XTR-5218806 https://reactome.org/PathwayBrowser/#/R-XTR-5218806 FYN autophosphorylates IEA Xenopus tropicalis 30616 R-XTR-5218812 https://reactome.org/PathwayBrowser/#/R-XTR-5218812 FYN phosphorylates PAK2 IEA Xenopus tropicalis 30616 R-XTR-5218814 https://reactome.org/PathwayBrowser/#/R-XTR-5218814 PAK2 autophorylates IEA Xenopus tropicalis 30616 R-XTR-5218819 https://reactome.org/PathwayBrowser/#/R-XTR-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-5218821 https://reactome.org/PathwayBrowser/#/R-XTR-5218821 PDK1 phosphorylates PKC IEA Xenopus tropicalis 30616 R-XTR-5218854 https://reactome.org/PathwayBrowser/#/R-XTR-5218854 p-Y420-FYN is phosphorylated on S21 IEA Xenopus tropicalis 30616 R-XTR-5229194 https://reactome.org/PathwayBrowser/#/R-XTR-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Xenopus tropicalis 30616 R-XTR-5244669 https://reactome.org/PathwayBrowser/#/R-XTR-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Xenopus tropicalis 30616 R-XTR-5251942 https://reactome.org/PathwayBrowser/#/R-XTR-5251942 Hikeshi binds HSP70s:ATP IEA Xenopus tropicalis 30616 R-XTR-5251955 https://reactome.org/PathwayBrowser/#/R-XTR-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Xenopus tropicalis 30616 R-XTR-5251959 https://reactome.org/PathwayBrowser/#/R-XTR-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Xenopus tropicalis 30616 R-XTR-5251989 https://reactome.org/PathwayBrowser/#/R-XTR-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Xenopus tropicalis 30616 R-XTR-5252041 https://reactome.org/PathwayBrowser/#/R-XTR-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Xenopus tropicalis 30616 R-XTR-5252079 https://reactome.org/PathwayBrowser/#/R-XTR-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Xenopus tropicalis 30616 R-XTR-5339524 https://reactome.org/PathwayBrowser/#/R-XTR-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 30616 R-XTR-5357472 https://reactome.org/PathwayBrowser/#/R-XTR-5357472 PAK1-3 autophosphorylates IEA Xenopus tropicalis 30616 R-XTR-5357477 https://reactome.org/PathwayBrowser/#/R-XTR-5357477 PAK1-3 phosphorylates VE-cadherin IEA Xenopus tropicalis 30616 R-XTR-5358475 https://reactome.org/PathwayBrowser/#/R-XTR-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Xenopus tropicalis 30616 R-XTR-5362459 https://reactome.org/PathwayBrowser/#/R-XTR-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Xenopus tropicalis 30616 R-XTR-548843 https://reactome.org/PathwayBrowser/#/R-XTR-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Xenopus tropicalis 30616 R-XTR-5603114 https://reactome.org/PathwayBrowser/#/R-XTR-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Xenopus tropicalis 30616 R-XTR-5607722 https://reactome.org/PathwayBrowser/#/R-XTR-5607722 Active NIK phosphorylates IKKA dimer IEA Xenopus tropicalis 30616 R-XTR-5607726 https://reactome.org/PathwayBrowser/#/R-XTR-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Xenopus tropicalis 30616 R-XTR-5607740 https://reactome.org/PathwayBrowser/#/R-XTR-5607740 PKC-delta phosphorylates CARD9 IEA Xenopus tropicalis 30616 R-XTR-5610720 https://reactome.org/PathwayBrowser/#/R-XTR-5610720 PKA phosphorylates GLI3 IEA Xenopus tropicalis 30616 R-XTR-5610727 https://reactome.org/PathwayBrowser/#/R-XTR-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Xenopus tropicalis 30616 R-XTR-5617179 https://reactome.org/PathwayBrowser/#/R-XTR-5617179 PRKACA phosphorylates TNNI3 IEA Xenopus tropicalis 30616 R-XTR-5617182 https://reactome.org/PathwayBrowser/#/R-XTR-5617182 PRKACA phosphorylates PLN IEA Xenopus tropicalis 30616 R-XTR-5618099 https://reactome.org/PathwayBrowser/#/R-XTR-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 30616 R-XTR-5618107 https://reactome.org/PathwayBrowser/#/R-XTR-5618107 ATP binding to HSP90 triggers conformation change IEA Xenopus tropicalis 30616 R-XTR-5621363 https://reactome.org/PathwayBrowser/#/R-XTR-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Xenopus tropicalis 30616 R-XTR-5623667 https://reactome.org/PathwayBrowser/#/R-XTR-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Xenopus tropicalis 30616 R-XTR-5624486 https://reactome.org/PathwayBrowser/#/R-XTR-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Xenopus tropicalis 30616 R-XTR-5624492 https://reactome.org/PathwayBrowser/#/R-XTR-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Xenopus tropicalis 30616 R-XTR-5626507 https://reactome.org/PathwayBrowser/#/R-XTR-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Xenopus tropicalis 30616 R-XTR-5627775 https://reactome.org/PathwayBrowser/#/R-XTR-5627775 Autophosphorylation of PAK1,2,3 IEA Xenopus tropicalis 30616 R-XTR-5654149 https://reactome.org/PathwayBrowser/#/R-XTR-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Xenopus tropicalis 30616 R-XTR-5654151 https://reactome.org/PathwayBrowser/#/R-XTR-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Xenopus tropicalis 30616 R-XTR-5654418 https://reactome.org/PathwayBrowser/#/R-XTR-5654418 Activated FGFR4 phosphorylates FRS2 IEA Xenopus tropicalis 30616 R-XTR-5654428 https://reactome.org/PathwayBrowser/#/R-XTR-5654428 Activated FGFR4 phosphorylates SHC1 IEA Xenopus tropicalis 30616 R-XTR-5654560 https://reactome.org/PathwayBrowser/#/R-XTR-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Xenopus tropicalis 30616 R-XTR-5654566 https://reactome.org/PathwayBrowser/#/R-XTR-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Xenopus tropicalis 30616 R-XTR-5654575 https://reactome.org/PathwayBrowser/#/R-XTR-5654575 Activated FGFR1 phosphorylates FRS2 IEA Xenopus tropicalis 30616 R-XTR-5654578 https://reactome.org/PathwayBrowser/#/R-XTR-5654578 Activated FGFR1 phosphorylates FRS3 IEA Xenopus tropicalis 30616 R-XTR-5654582 https://reactome.org/PathwayBrowser/#/R-XTR-5654582 Activated FGFR1 phosphorylates SHC1 IEA Xenopus tropicalis 30616 R-XTR-5654587 https://reactome.org/PathwayBrowser/#/R-XTR-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Xenopus tropicalis 30616 R-XTR-5654607 https://reactome.org/PathwayBrowser/#/R-XTR-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Xenopus tropicalis 30616 R-XTR-5654631 https://reactome.org/PathwayBrowser/#/R-XTR-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Xenopus tropicalis 30616 R-XTR-5654653 https://reactome.org/PathwayBrowser/#/R-XTR-5654653 Activated FGFR4 phosphorylates FRS3 IEA Xenopus tropicalis 30616 R-XTR-5654655 https://reactome.org/PathwayBrowser/#/R-XTR-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Xenopus tropicalis 30616 R-XTR-5654690 https://reactome.org/PathwayBrowser/#/R-XTR-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-5654692 https://reactome.org/PathwayBrowser/#/R-XTR-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-5654697 https://reactome.org/PathwayBrowser/#/R-XTR-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-5654701 https://reactome.org/PathwayBrowser/#/R-XTR-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-5654705 https://reactome.org/PathwayBrowser/#/R-XTR-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-5654709 https://reactome.org/PathwayBrowser/#/R-XTR-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-5654714 https://reactome.org/PathwayBrowser/#/R-XTR-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-5654717 https://reactome.org/PathwayBrowser/#/R-XTR-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-5654989 https://reactome.org/PathwayBrowser/#/R-XTR-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Xenopus tropicalis 30616 R-XTR-5662466 https://reactome.org/PathwayBrowser/#/R-XTR-5662466 XYLB phosphorylates D-xylulose IEA Xenopus tropicalis 30616 R-XTR-5665868 https://reactome.org/PathwayBrowser/#/R-XTR-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Xenopus tropicalis 30616 R-XTR-5666001 https://reactome.org/PathwayBrowser/#/R-XTR-5666001 Profilin:G-actin binds MKL1 IEA Xenopus tropicalis 30616 R-XTR-5668545 https://reactome.org/PathwayBrowser/#/R-XTR-5668545 NIK autophosphorylates on T559 IEA Xenopus tropicalis 30616 R-XTR-5668947 https://reactome.org/PathwayBrowser/#/R-XTR-5668947 PAK1 phosphorylates myosin phosphatase IEA Xenopus tropicalis 30616 R-XTR-5669250 https://reactome.org/PathwayBrowser/#/R-XTR-5669250 PAK1 phosphorylates FLNA IEA Xenopus tropicalis 30616 R-XTR-5672008 https://reactome.org/PathwayBrowser/#/R-XTR-5672008 Thr-180 of ULK1 is phosphorylated IEA Xenopus tropicalis 30616 R-XTR-5672010 https://reactome.org/PathwayBrowser/#/R-XTR-5672010 Active MTORC1 phosphorylates ULK1 IEA Xenopus tropicalis 30616 R-XTR-5672012 https://reactome.org/PathwayBrowser/#/R-XTR-5672012 Beclin-1 complex phosphorylates PtdIns IEA Xenopus tropicalis 30616 R-XTR-5672027 https://reactome.org/PathwayBrowser/#/R-XTR-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Xenopus tropicalis 30616 R-XTR-5672828 https://reactome.org/PathwayBrowser/#/R-XTR-5672828 mTORC1 phosphorylates AKT1S1 IEA Xenopus tropicalis 30616 R-XTR-5675194 https://reactome.org/PathwayBrowser/#/R-XTR-5675194 Activated MAPK phosphorylates RAF1 IEA Xenopus tropicalis 30616 R-XTR-5675868 https://reactome.org/PathwayBrowser/#/R-XTR-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Xenopus tropicalis 30616 R-XTR-5678863 https://reactome.org/PathwayBrowser/#/R-XTR-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Xenopus tropicalis 30616 R-XTR-5679041 https://reactome.org/PathwayBrowser/#/R-XTR-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 30616 R-XTR-5679205 https://reactome.org/PathwayBrowser/#/R-XTR-5679205 ULK1 phosphorylates Beclin-1 IEA Xenopus tropicalis 30616 R-XTR-5682101 https://reactome.org/PathwayBrowser/#/R-XTR-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Xenopus tropicalis 30616 R-XTR-5683714 https://reactome.org/PathwayBrowser/#/R-XTR-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Xenopus tropicalis 30616 R-XTR-5683792 https://reactome.org/PathwayBrowser/#/R-XTR-5683792 p-T68-CHEK2 autophosphorylates IEA Xenopus tropicalis 30616 R-XTR-5684261 https://reactome.org/PathwayBrowser/#/R-XTR-5684261 MAP3K8 is phosphorylated IEA Xenopus tropicalis 30616 R-XTR-5685156 https://reactome.org/PathwayBrowser/#/R-XTR-5685156 ATR phosphorylates RPA2 IEA Xenopus tropicalis 30616 R-XTR-5686587 https://reactome.org/PathwayBrowser/#/R-XTR-5686587 ABL1 phosphorylates RAD52 IEA Xenopus tropicalis 30616 R-XTR-5687086 https://reactome.org/PathwayBrowser/#/R-XTR-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Xenopus tropicalis 30616 R-XTR-5687090 https://reactome.org/PathwayBrowser/#/R-XTR-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Xenopus tropicalis 30616 R-XTR-5690996 https://reactome.org/PathwayBrowser/#/R-XTR-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Xenopus tropicalis 30616 R-XTR-5692462 https://reactome.org/PathwayBrowser/#/R-XTR-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Xenopus tropicalis 30616 R-XTR-5692480 https://reactome.org/PathwayBrowser/#/R-XTR-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Xenopus tropicalis 30616 R-XTR-5692755 https://reactome.org/PathwayBrowser/#/R-XTR-5692755 CDK1 phosphorylates MAPK6 IEA Xenopus tropicalis 30616 R-XTR-5693148 https://reactome.org/PathwayBrowser/#/R-XTR-5693148 BCKDK phosphorylates BCKDH IEA Xenopus tropicalis 30616 R-XTR-5694494 https://reactome.org/PathwayBrowser/#/R-XTR-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Xenopus tropicalis 30616 R-XTR-5696004 https://reactome.org/PathwayBrowser/#/R-XTR-5696004 ACSF2 ligates CoA-SH to MCFA IEA Xenopus tropicalis 30616 R-XTR-5696074 https://reactome.org/PathwayBrowser/#/R-XTR-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Xenopus tropicalis 30616 R-XTR-5696839 https://reactome.org/PathwayBrowser/#/R-XTR-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Xenopus tropicalis 30616 R-XTR-6782131 https://reactome.org/PathwayBrowser/#/R-XTR-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Xenopus tropicalis 30616 R-XTR-6784006 https://reactome.org/PathwayBrowser/#/R-XTR-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Xenopus tropicalis 30616 R-XTR-6784319 https://reactome.org/PathwayBrowser/#/R-XTR-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Xenopus tropicalis 30616 R-XTR-6784324 https://reactome.org/PathwayBrowser/#/R-XTR-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Xenopus tropicalis 30616 R-XTR-6786245 https://reactome.org/PathwayBrowser/#/R-XTR-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Xenopus tropicalis 30616 R-XTR-6787540 https://reactome.org/PathwayBrowser/#/R-XTR-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Xenopus tropicalis 30616 R-XTR-6788798 https://reactome.org/PathwayBrowser/#/R-XTR-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 30616 R-XTR-6788810 https://reactome.org/PathwayBrowser/#/R-XTR-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 30616 R-XTR-6788855 https://reactome.org/PathwayBrowser/#/R-XTR-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Xenopus tropicalis 30616 R-XTR-6788867 https://reactome.org/PathwayBrowser/#/R-XTR-6788867 FN3K phosphorylates ketosamines IEA Xenopus tropicalis 30616 R-XTR-6793661 https://reactome.org/PathwayBrowser/#/R-XTR-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Xenopus tropicalis 30616 R-XTR-6797606 https://reactome.org/PathwayBrowser/#/R-XTR-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Xenopus tropicalis 30616 R-XTR-6799332 https://reactome.org/PathwayBrowser/#/R-XTR-6799332 ATR phosphorylates TP53 IEA Xenopus tropicalis 30616 R-XTR-6801342 https://reactome.org/PathwayBrowser/#/R-XTR-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Xenopus tropicalis 30616 R-XTR-6801456 https://reactome.org/PathwayBrowser/#/R-XTR-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Xenopus tropicalis 30616 R-XTR-6801675 https://reactome.org/PathwayBrowser/#/R-XTR-6801675 PLK2 phosphorylates NPM1 IEA Xenopus tropicalis 30616 R-XTR-6803545 https://reactome.org/PathwayBrowser/#/R-XTR-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Xenopus tropicalis 30616 R-XTR-6804596 https://reactome.org/PathwayBrowser/#/R-XTR-6804596 APAF1:CYCS binds APIP IEA Xenopus tropicalis 30616 R-XTR-6805059 https://reactome.org/PathwayBrowser/#/R-XTR-6805059 CK2:FACT phosphorylates TP53 IEA Xenopus tropicalis 30616 R-XTR-6805103 https://reactome.org/PathwayBrowser/#/R-XTR-6805103 AURKA phosphorylates TP53 IEA Xenopus tropicalis 30616 R-XTR-6805109 https://reactome.org/PathwayBrowser/#/R-XTR-6805109 CDK2 phosphorylates TP53 IEA Xenopus tropicalis 30616 R-XTR-6805126 https://reactome.org/PathwayBrowser/#/R-XTR-6805126 AURKB phosphorylates TP53 IEA Xenopus tropicalis 30616 R-XTR-6805276 https://reactome.org/PathwayBrowser/#/R-XTR-6805276 CDK5 phosphorylates TP53 IEA Xenopus tropicalis 30616 R-XTR-6805285 https://reactome.org/PathwayBrowser/#/R-XTR-6805285 PLK3 phosphorylates TP53 IEA Xenopus tropicalis 30616 R-XTR-6805399 https://reactome.org/PathwayBrowser/#/R-XTR-6805399 TAF1 phosphorylates TP53 IEA Xenopus tropicalis 30616 R-XTR-6805479 https://reactome.org/PathwayBrowser/#/R-XTR-6805479 TP53RK phosphorylates TP53 IEA Xenopus tropicalis 30616 R-XTR-6806877 https://reactome.org/PathwayBrowser/#/R-XTR-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Xenopus tropicalis 30616 R-XTR-6806967 https://reactome.org/PathwayBrowser/#/R-XTR-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Xenopus tropicalis 30616 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 30616 R-XTR-6809015 https://reactome.org/PathwayBrowser/#/R-XTR-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Xenopus tropicalis 30616 R-XTR-6810233 https://reactome.org/PathwayBrowser/#/R-XTR-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Xenopus tropicalis 30616 R-XTR-6811522 https://reactome.org/PathwayBrowser/#/R-XTR-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Xenopus tropicalis 30616 R-XTR-6814120 https://reactome.org/PathwayBrowser/#/R-XTR-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Xenopus tropicalis 30616 R-XTR-6814124 https://reactome.org/PathwayBrowser/#/R-XTR-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Xenopus tropicalis 30616 R-XTR-6814559 https://reactome.org/PathwayBrowser/#/R-XTR-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Xenopus tropicalis 30616 R-XTR-68610 https://reactome.org/PathwayBrowser/#/R-XTR-68610 Formation of ORC(2-5) complex IEA Xenopus tropicalis 30616 R-XTR-68944 https://reactome.org/PathwayBrowser/#/R-XTR-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Xenopus tropicalis 30616 R-XTR-69005 https://reactome.org/PathwayBrowser/#/R-XTR-69005 Cdc6 protein is phosphorylated by CDK IEA Xenopus tropicalis 30616 R-XTR-69015 https://reactome.org/PathwayBrowser/#/R-XTR-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Xenopus tropicalis 30616 R-XTR-69195 https://reactome.org/PathwayBrowser/#/R-XTR-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Xenopus tropicalis 30616 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 30616 R-XTR-69608 https://reactome.org/PathwayBrowser/#/R-XTR-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Xenopus tropicalis 30616 R-XTR-69685 https://reactome.org/PathwayBrowser/#/R-XTR-69685 CHEK2 phosphorylates TP53 IEA Xenopus tropicalis 30616 R-XTR-70355 https://reactome.org/PathwayBrowser/#/R-XTR-70355 GALK1 phosphorylates Gal to Gal1P IEA Xenopus tropicalis 30616 R-XTR-70420 https://reactome.org/PathwayBrowser/#/R-XTR-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Xenopus tropicalis 30616 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 30616 R-XTR-70555 https://reactome.org/PathwayBrowser/#/R-XTR-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Xenopus tropicalis 30616 R-XTR-70599 https://reactome.org/PathwayBrowser/#/R-XTR-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Xenopus tropicalis 30616 R-XTR-70606 https://reactome.org/PathwayBrowser/#/R-XTR-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Xenopus tropicalis 30616 R-XTR-70773 https://reactome.org/PathwayBrowser/#/R-XTR-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Xenopus tropicalis 30616 R-XTR-70997 https://reactome.org/PathwayBrowser/#/R-XTR-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Xenopus tropicalis 30616 R-XTR-71031 https://reactome.org/PathwayBrowser/#/R-XTR-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Xenopus tropicalis 30616 R-XTR-71401 https://reactome.org/PathwayBrowser/#/R-XTR-71401 OGDH dimer decarboxylates 2-OG IEA Xenopus tropicalis 30616 R-XTR-71588 https://reactome.org/PathwayBrowser/#/R-XTR-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Xenopus tropicalis 30616 R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 30616 R-XTR-71735 https://reactome.org/PathwayBrowser/#/R-XTR-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Xenopus tropicalis 30616 R-XTR-71802 https://reactome.org/PathwayBrowser/#/R-XTR-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Xenopus tropicalis 30616 R-XTR-72621 https://reactome.org/PathwayBrowser/#/R-XTR-72621 Ribosomal scanning IEA Xenopus tropicalis 30616 R-XTR-727819 https://reactome.org/PathwayBrowser/#/R-XTR-727819 TAK1 phosphorylates MKK6 IEA Xenopus tropicalis 30616 R-XTR-73577 https://reactome.org/PathwayBrowser/#/R-XTR-73577 CAD hexamer transforms L-Gln to CAP IEA Xenopus tropicalis 30616 R-XTR-73580 https://reactome.org/PathwayBrowser/#/R-XTR-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Xenopus tropicalis 30616 R-XTR-73598 https://reactome.org/PathwayBrowser/#/R-XTR-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Xenopus tropicalis 30616 R-XTR-73599 https://reactome.org/PathwayBrowser/#/R-XTR-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Xenopus tropicalis 30616 R-XTR-73632 https://reactome.org/PathwayBrowser/#/R-XTR-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Xenopus tropicalis 30616 R-XTR-73635 https://reactome.org/PathwayBrowser/#/R-XTR-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Xenopus tropicalis 30616 R-XTR-73788 https://reactome.org/PathwayBrowser/#/R-XTR-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Xenopus tropicalis 30616 R-XTR-73792 https://reactome.org/PathwayBrowser/#/R-XTR-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Xenopus tropicalis 30616 R-XTR-73805 https://reactome.org/PathwayBrowser/#/R-XTR-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Xenopus tropicalis 30616 R-XTR-73810 https://reactome.org/PathwayBrowser/#/R-XTR-73810 FGAM + ATP => AIR + ADP + Pi IEA Xenopus tropicalis 30616 R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 30616 R-XTR-73814 https://reactome.org/PathwayBrowser/#/R-XTR-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Xenopus tropicalis 30616 R-XTR-74207 https://reactome.org/PathwayBrowser/#/R-XTR-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Xenopus tropicalis 30616 R-XTR-74711 https://reactome.org/PathwayBrowser/#/R-XTR-74711 Phosphorylation of IRS IEA Xenopus tropicalis 30616 R-XTR-74715 https://reactome.org/PathwayBrowser/#/R-XTR-74715 Autophosphorylation of insulin receptor IEA Xenopus tropicalis 30616 R-XTR-74742 https://reactome.org/PathwayBrowser/#/R-XTR-74742 Phosphorylation of SHC1 IEA Xenopus tropicalis 30616 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 30616 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 30616 R-XTR-75126 https://reactome.org/PathwayBrowser/#/R-XTR-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Xenopus tropicalis 30616 R-XTR-75848 https://reactome.org/PathwayBrowser/#/R-XTR-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Xenopus tropicalis 30616 R-XTR-75851 https://reactome.org/PathwayBrowser/#/R-XTR-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 30616 R-XTR-75887 https://reactome.org/PathwayBrowser/#/R-XTR-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Xenopus tropicalis 30616 R-XTR-75949 https://reactome.org/PathwayBrowser/#/R-XTR-75949 RNA Polymerase II Promoter Opening: First Transition IEA Xenopus tropicalis 30616 R-XTR-77071 https://reactome.org/PathwayBrowser/#/R-XTR-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Xenopus tropicalis 30616 R-XTR-8847977 https://reactome.org/PathwayBrowser/#/R-XTR-8847977 FRK phosphorylates PTEN IEA Xenopus tropicalis 30616 R-XTR-8848053 https://reactome.org/PathwayBrowser/#/R-XTR-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Xenopus tropicalis 30616 R-XTR-8848436 https://reactome.org/PathwayBrowser/#/R-XTR-8848436 PTK6 phosphorylates CDKN1B IEA Xenopus tropicalis 30616 R-XTR-8848726 https://reactome.org/PathwayBrowser/#/R-XTR-8848726 PTK6 phosphorylates BCAR1 IEA Xenopus tropicalis 30616 R-XTR-8848975 https://reactome.org/PathwayBrowser/#/R-XTR-8848975 PTK6 phosphorylates KHDRBS1 IEA Xenopus tropicalis 30616 R-XTR-8849032 https://reactome.org/PathwayBrowser/#/R-XTR-8849032 PTK6 phosphorylates KHDRBS2 IEA Xenopus tropicalis 30616 R-XTR-8849042 https://reactome.org/PathwayBrowser/#/R-XTR-8849042 PTK6 phosphorylates KHDRBS3 IEA Xenopus tropicalis 30616 R-XTR-8849068 https://reactome.org/PathwayBrowser/#/R-XTR-8849068 PTK6 phosphorylates ARHGAP35 IEA Xenopus tropicalis 30616 R-XTR-8849463 https://reactome.org/PathwayBrowser/#/R-XTR-8849463 PTK6 phosphorylates SFPQ IEA Xenopus tropicalis 30616 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 30616 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 30616 R-XTR-8851797 https://reactome.org/PathwayBrowser/#/R-XTR-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Xenopus tropicalis 30616 R-XTR-8851890 https://reactome.org/PathwayBrowser/#/R-XTR-8851890 MET phosphorylates SHC1-2 IEA Xenopus tropicalis 30616 R-XTR-8851933 https://reactome.org/PathwayBrowser/#/R-XTR-8851933 MET phosphorylates GAB1 IEA Xenopus tropicalis 30616 R-XTR-8852019 https://reactome.org/PathwayBrowser/#/R-XTR-8852019 MET bound PI3K generates PIP3 IEA Xenopus tropicalis 30616 R-XTR-8852128 https://reactome.org/PathwayBrowser/#/R-XTR-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Xenopus tropicalis 30616 R-XTR-8852131 https://reactome.org/PathwayBrowser/#/R-XTR-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Xenopus tropicalis 30616 R-XTR-8852132 https://reactome.org/PathwayBrowser/#/R-XTR-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Xenopus tropicalis 30616 R-XTR-8852134 https://reactome.org/PathwayBrowser/#/R-XTR-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Xenopus tropicalis 30616 R-XTR-8852306 https://reactome.org/PathwayBrowser/#/R-XTR-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Xenopus tropicalis 30616 R-XTR-8852317 https://reactome.org/PathwayBrowser/#/R-XTR-8852317 PLK1 phosphorylates GTSE1 IEA Xenopus tropicalis 30616 R-XTR-8852552 https://reactome.org/PathwayBrowser/#/R-XTR-8852552 MST1R autophosphorylates IEA Xenopus tropicalis 30616 R-XTR-8853419 https://reactome.org/PathwayBrowser/#/R-XTR-8853419 TPX2 promotes AURKA autophosphorylation IEA Xenopus tropicalis 30616 R-XTR-8853444 https://reactome.org/PathwayBrowser/#/R-XTR-8853444 AURKA phosphorylates PHLDA1 IEA Xenopus tropicalis 30616 R-XTR-8853774 https://reactome.org/PathwayBrowser/#/R-XTR-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Xenopus tropicalis 30616 R-XTR-8857555 https://reactome.org/PathwayBrowser/#/R-XTR-8857555 EGFR phosphorylates GPNMB IEA Xenopus tropicalis 30616 R-XTR-8857577 https://reactome.org/PathwayBrowser/#/R-XTR-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Xenopus tropicalis 30616 R-XTR-8857583 https://reactome.org/PathwayBrowser/#/R-XTR-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Xenopus tropicalis 30616 R-XTR-8865774 https://reactome.org/PathwayBrowser/#/R-XTR-8865774 TTLLs polyglutamylate tubulin IEA Xenopus tropicalis 30616 R-XTR-8866268 https://reactome.org/PathwayBrowser/#/R-XTR-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Xenopus tropicalis 30616 R-XTR-8866405 https://reactome.org/PathwayBrowser/#/R-XTR-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 30616 R-XTR-8866542 https://reactome.org/PathwayBrowser/#/R-XTR-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Xenopus tropicalis 30616 R-XTR-8867370 https://reactome.org/PathwayBrowser/#/R-XTR-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Xenopus tropicalis 30616 R-XTR-8868066 https://reactome.org/PathwayBrowser/#/R-XTR-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Xenopus tropicalis 30616 R-XTR-8868118 https://reactome.org/PathwayBrowser/#/R-XTR-8868118 MAPK12 phosphorylates PTPN3 IEA Xenopus tropicalis 30616 R-XTR-8875071 https://reactome.org/PathwayBrowser/#/R-XTR-8875071 ACSS3 ligates CoA to CH3COO- IEA Xenopus tropicalis 30616 R-XTR-8875451 https://reactome.org/PathwayBrowser/#/R-XTR-8875451 MET phosphorylates CBL IEA Xenopus tropicalis 30616 R-XTR-8875817 https://reactome.org/PathwayBrowser/#/R-XTR-8875817 MET phosphorylates STAT3 IEA Xenopus tropicalis 30616 R-XTR-8876889 https://reactome.org/PathwayBrowser/#/R-XTR-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 30616 R-XTR-8877691 https://reactome.org/PathwayBrowser/#/R-XTR-8877691 MAP2K6 phosphorylates PIP4K2B IEA Xenopus tropicalis 30616 R-XTR-8931653 https://reactome.org/PathwayBrowser/#/R-XTR-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Xenopus tropicalis 30616 R-XTR-8939204 https://reactome.org/PathwayBrowser/#/R-XTR-8939204 ESTG binds ESR1:chaperone complex IEA Xenopus tropicalis 30616 R-XTR-8940100 https://reactome.org/PathwayBrowser/#/R-XTR-8940100 CDK1 phosphorylates VCPIP1 IEA Xenopus tropicalis 30616 R-XTR-8942575 https://reactome.org/PathwayBrowser/#/R-XTR-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Xenopus tropicalis 30616 R-XTR-8942607 https://reactome.org/PathwayBrowser/#/R-XTR-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Xenopus tropicalis 30616 R-XTR-8942836 https://reactome.org/PathwayBrowser/#/R-XTR-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Xenopus tropicalis 30616 R-XTR-8948146 https://reactome.org/PathwayBrowser/#/R-XTR-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Xenopus tropicalis 30616 R-XTR-8950340 https://reactome.org/PathwayBrowser/#/R-XTR-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Xenopus tropicalis 30616 R-XTR-8950405 https://reactome.org/PathwayBrowser/#/R-XTR-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Xenopus tropicalis 30616 R-XTR-8950453 https://reactome.org/PathwayBrowser/#/R-XTR-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Xenopus tropicalis 30616 R-XTR-8950485 https://reactome.org/PathwayBrowser/#/R-XTR-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Xenopus tropicalis 30616 R-XTR-8950537 https://reactome.org/PathwayBrowser/#/R-XTR-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Xenopus tropicalis 30616 R-XTR-8952289 https://reactome.org/PathwayBrowser/#/R-XTR-8952289 FAM20C phosphorylates FAM20C substrates IEA Xenopus tropicalis 30616 R-XTR-8954327 https://reactome.org/PathwayBrowser/#/R-XTR-8954327 UCKL1 phosphorylates urindine, cytidine IEA Xenopus tropicalis 30616 R-XTR-8955030 https://reactome.org/PathwayBrowser/#/R-XTR-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 30616 R-XTR-8955844 https://reactome.org/PathwayBrowser/#/R-XTR-8955844 RBKS phosphorylates ribose to R5P IEA Xenopus tropicalis 30616 R-XTR-8956659 https://reactome.org/PathwayBrowser/#/R-XTR-8956659 ABL1 phosphorylates YAP1 IEA Xenopus tropicalis 30616 R-XTR-8959719 https://reactome.org/PathwayBrowser/#/R-XTR-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Xenopus tropicalis 30616 R-XTR-8983834 https://reactome.org/PathwayBrowser/#/R-XTR-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Xenopus tropicalis 30616 R-XTR-8983835 https://reactome.org/PathwayBrowser/#/R-XTR-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Xenopus tropicalis 30616 R-XTR-8983870 https://reactome.org/PathwayBrowser/#/R-XTR-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Xenopus tropicalis 30616 R-XTR-8983872 https://reactome.org/PathwayBrowser/#/R-XTR-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Xenopus tropicalis 30616 R-XTR-8984012 https://reactome.org/PathwayBrowser/#/R-XTR-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Xenopus tropicalis 30616 R-XTR-8984014 https://reactome.org/PathwayBrowser/#/R-XTR-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Xenopus tropicalis 30616 R-XTR-8986985 https://reactome.org/PathwayBrowser/#/R-XTR-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Xenopus tropicalis 30616 R-XTR-8986994 https://reactome.org/PathwayBrowser/#/R-XTR-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Xenopus tropicalis 30616 R-XTR-8986995 https://reactome.org/PathwayBrowser/#/R-XTR-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Xenopus tropicalis 30616 R-XTR-8987040 https://reactome.org/PathwayBrowser/#/R-XTR-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Xenopus tropicalis 30616 R-XTR-8987042 https://reactome.org/PathwayBrowser/#/R-XTR-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Xenopus tropicalis 30616 R-XTR-8987070 https://reactome.org/PathwayBrowser/#/R-XTR-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Xenopus tropicalis 30616 R-XTR-8987202 https://reactome.org/PathwayBrowser/#/R-XTR-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Xenopus tropicalis 30616 R-XTR-8987255 https://reactome.org/PathwayBrowser/#/R-XTR-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Xenopus tropicalis 30616 R-XTR-9008684 https://reactome.org/PathwayBrowser/#/R-XTR-9008684 TBK1 phosphorylation IEA Xenopus tropicalis 30616 R-XTR-9009072 https://reactome.org/PathwayBrowser/#/R-XTR-9009072 STAT3 phosphorylation IEA Xenopus tropicalis 30616 R-XTR-9009936 https://reactome.org/PathwayBrowser/#/R-XTR-9009936 RNASEL cleaves cellular ssRNA IEA Xenopus tropicalis 30616 R-XTR-9012268 https://reactome.org/PathwayBrowser/#/R-XTR-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 30616 R-XTR-9012319 https://reactome.org/PathwayBrowser/#/R-XTR-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Xenopus tropicalis 30616 R-XTR-9014741 https://reactome.org/PathwayBrowser/#/R-XTR-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Xenopus tropicalis 30616 R-XTR-9014766 https://reactome.org/PathwayBrowser/#/R-XTR-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Xenopus tropicalis 30616 R-XTR-9018572 https://reactome.org/PathwayBrowser/#/R-XTR-9018572 EGFR phosphorylates NOTCH3 IEA Xenopus tropicalis 30616 R-XTR-9021627 https://reactome.org/PathwayBrowser/#/R-XTR-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 30616 R-XTR-9027272 https://reactome.org/PathwayBrowser/#/R-XTR-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Xenopus tropicalis 30616 R-XTR-9027273 https://reactome.org/PathwayBrowser/#/R-XTR-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Xenopus tropicalis 30616 R-XTR-909718 https://reactome.org/PathwayBrowser/#/R-XTR-909718 Formation of p-STAT1 homodimer IEA Xenopus tropicalis 30616 R-XTR-909729 https://reactome.org/PathwayBrowser/#/R-XTR-909729 Activation of JAK kinases IEA Xenopus tropicalis 30616 R-XTR-909730 https://reactome.org/PathwayBrowser/#/R-XTR-909730 Phosphorylation of INFAR1 by TYK2 IEA Xenopus tropicalis 30616 R-XTR-909732 https://reactome.org/PathwayBrowser/#/R-XTR-909732 Phosphorylation of STAT2 IEA Xenopus tropicalis 30616 R-XTR-913996 https://reactome.org/PathwayBrowser/#/R-XTR-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Xenopus tropicalis 30616 R-XTR-917693 https://reactome.org/PathwayBrowser/#/R-XTR-917693 ESCRT Disassembly IEA Xenopus tropicalis 30616 R-XTR-917841 https://reactome.org/PathwayBrowser/#/R-XTR-917841 Acidification of Tf:TfR1 containing endosome IEA Xenopus tropicalis 30616 R-XTR-917979 https://reactome.org/PathwayBrowser/#/R-XTR-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Xenopus tropicalis 30616 R-XTR-927889 https://reactome.org/PathwayBrowser/#/R-XTR-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Xenopus tropicalis 30616 R-XTR-934559 https://reactome.org/PathwayBrowser/#/R-XTR-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Xenopus tropicalis 30616 R-XTR-936802 https://reactome.org/PathwayBrowser/#/R-XTR-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Xenopus tropicalis 30616 R-XTR-936883 https://reactome.org/PathwayBrowser/#/R-XTR-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Xenopus tropicalis 30616 R-XTR-936895 https://reactome.org/PathwayBrowser/#/R-XTR-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Xenopus tropicalis 30616 R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 30616 R-XTR-936991 https://reactome.org/PathwayBrowser/#/R-XTR-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Xenopus tropicalis 30616 R-XTR-937311 https://reactome.org/PathwayBrowser/#/R-XTR-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 30616 R-XTR-939763 https://reactome.org/PathwayBrowser/#/R-XTR-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Xenopus tropicalis 30616 R-XTR-947591 https://reactome.org/PathwayBrowser/#/R-XTR-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Xenopus tropicalis 30616 R-XTR-9606884 https://reactome.org/PathwayBrowser/#/R-XTR-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Xenopus tropicalis 30616 R-XTR-9613494 https://reactome.org/PathwayBrowser/#/R-XTR-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Xenopus tropicalis 30616 R-XTR-9624800 https://reactome.org/PathwayBrowser/#/R-XTR-9624800 CDK1 phosphorylates LBR IEA Xenopus tropicalis 30616 R-XTR-9626817 https://reactome.org/PathwayBrowser/#/R-XTR-9626817 PKC phosphorylates NCF1 IEA Xenopus tropicalis 30616 R-XTR-9626832 https://reactome.org/PathwayBrowser/#/R-XTR-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Xenopus tropicalis 30616 R-XTR-9626880 https://reactome.org/PathwayBrowser/#/R-XTR-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Xenopus tropicalis 30616 R-XTR-9627056 https://reactome.org/PathwayBrowser/#/R-XTR-9627056 Procaspase 9 forms dimer IEA Xenopus tropicalis 30616 R-XTR-9627089 https://reactome.org/PathwayBrowser/#/R-XTR-9627089 CASP9 is phosphorylated at T412 IEA Xenopus tropicalis 30616 R-XTR-9634702 https://reactome.org/PathwayBrowser/#/R-XTR-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Xenopus tropicalis 30616 R-XTR-9645442 https://reactome.org/PathwayBrowser/#/R-XTR-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Xenopus tropicalis 30616 R-XTR-9645535 https://reactome.org/PathwayBrowser/#/R-XTR-9645535 ALPK1 phosphorylates TIFA IEA Xenopus tropicalis 30616 R-XTR-964958 https://reactome.org/PathwayBrowser/#/R-XTR-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Xenopus tropicalis 30616 R-XTR-964962 https://reactome.org/PathwayBrowser/#/R-XTR-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Xenopus tropicalis 30616 R-XTR-964970 https://reactome.org/PathwayBrowser/#/R-XTR-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Xenopus tropicalis 30616 R-XTR-9661417 https://reactome.org/PathwayBrowser/#/R-XTR-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 30616 R-XTR-9668419 https://reactome.org/PathwayBrowser/#/R-XTR-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Xenopus tropicalis 30616 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 30616 R-XTR-9684118 https://reactome.org/PathwayBrowser/#/R-XTR-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Xenopus tropicalis 30616 R-XTR-9686521 https://reactome.org/PathwayBrowser/#/R-XTR-9686521 CDK2:CCNA phosphorylates TERF2 IEA Xenopus tropicalis 30616 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 30616 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 30616 R-XTR-9705925 https://reactome.org/PathwayBrowser/#/R-XTR-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Xenopus tropicalis 30616 R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 30616 R-XTR-9706837 https://reactome.org/PathwayBrowser/#/R-XTR-9706837 AR binds AR antagonists IEA Xenopus tropicalis 30616 R-XTR-9709547 https://reactome.org/PathwayBrowser/#/R-XTR-9709547 ESTG binds ESR2:chaperone complex IEA Xenopus tropicalis 30616 R-XTR-9716913 https://reactome.org/PathwayBrowser/#/R-XTR-9716913 ESR1 binds ESR1 antagonists IEA Xenopus tropicalis 30616 R-XTR-9716947 https://reactome.org/PathwayBrowser/#/R-XTR-9716947 ESR1 binds ESR1 agonists IEA Xenopus tropicalis 30616 R-XTR-9725855 https://reactome.org/PathwayBrowser/#/R-XTR-9725855 NR3C2 binds NR3C2 antagonists IEA Xenopus tropicalis 30616 R-XTR-9726509 https://reactome.org/PathwayBrowser/#/R-XTR-9726509 NR3C2 binds fludrocortisone IEA Xenopus tropicalis 30616 R-XTR-9727198 https://reactome.org/PathwayBrowser/#/R-XTR-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 30616 R-XTR-9731111 https://reactome.org/PathwayBrowser/#/R-XTR-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Xenopus tropicalis 30616 R-XTR-9734535 https://reactome.org/PathwayBrowser/#/R-XTR-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Xenopus tropicalis 30616 R-XTR-9734547 https://reactome.org/PathwayBrowser/#/R-XTR-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Xenopus tropicalis 30616 R-XTR-9734687 https://reactome.org/PathwayBrowser/#/R-XTR-9734687 ORC6 is phosphorylated on T195 IEA Xenopus tropicalis 30616 R-XTR-9748949 https://reactome.org/PathwayBrowser/#/R-XTR-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Xenopus tropicalis 30616 R-XTR-9748957 https://reactome.org/PathwayBrowser/#/R-XTR-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Xenopus tropicalis 30616 R-XTR-9748963 https://reactome.org/PathwayBrowser/#/R-XTR-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Xenopus tropicalis 30616 R-XTR-9749971 https://reactome.org/PathwayBrowser/#/R-XTR-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Xenopus tropicalis 30616 R-XTR-9750617 https://reactome.org/PathwayBrowser/#/R-XTR-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Xenopus tropicalis 30616 R-XTR-9750656 https://reactome.org/PathwayBrowser/#/R-XTR-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Xenopus tropicalis 30616 R-XTR-975103 https://reactome.org/PathwayBrowser/#/R-XTR-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Xenopus tropicalis 30616 R-XTR-9753278 https://reactome.org/PathwayBrowser/#/R-XTR-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 30616 R-XTR-9753283 https://reactome.org/PathwayBrowser/#/R-XTR-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 30616 R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 30616 R-XTR-9754974 https://reactome.org/PathwayBrowser/#/R-XTR-9754974 ADK phosphorylates RBV IEA Xenopus tropicalis 30616 R-XTR-9755013 https://reactome.org/PathwayBrowser/#/R-XTR-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Xenopus tropicalis 30616 R-XTR-9794120 https://reactome.org/PathwayBrowser/#/R-XTR-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Xenopus tropicalis 30616 R-XTR-9794572 https://reactome.org/PathwayBrowser/#/R-XTR-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Xenopus tropicalis 30616 R-XTR-9819106 https://reactome.org/PathwayBrowser/#/R-XTR-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Xenopus tropicalis 30616 R-XTR-9824977 https://reactome.org/PathwayBrowser/#/R-XTR-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Xenopus tropicalis 30616 R-XTR-9824994 https://reactome.org/PathwayBrowser/#/R-XTR-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Xenopus tropicalis 30616 R-XTR-982810 https://reactome.org/PathwayBrowser/#/R-XTR-982810 JAK2 phosphorylation IEA Xenopus tropicalis 30616 R-XTR-983140 https://reactome.org/PathwayBrowser/#/R-XTR-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Xenopus tropicalis 30616 R-XTR-983153 https://reactome.org/PathwayBrowser/#/R-XTR-983153 E1 mediated ubiquitin activation IEA Xenopus tropicalis 30616 R-XTR-983156 https://reactome.org/PathwayBrowser/#/R-XTR-983156 Polyubiquitination of substrate IEA Xenopus tropicalis 30616 R-XTR-983259 https://reactome.org/PathwayBrowser/#/R-XTR-983259 Kinesins move along microtubules consuming ATP IEA Xenopus tropicalis 30616 R-XTR-9836159 https://reactome.org/PathwayBrowser/#/R-XTR-9836159 p-PKR dimer phosphorylates DHX9 IEA Xenopus tropicalis 30616 R-XTR-9836184 https://reactome.org/PathwayBrowser/#/R-XTR-9836184 p-PKR dimer phosphorylates CDK1 IEA Xenopus tropicalis 30616 R-XTR-9836322 https://reactome.org/PathwayBrowser/#/R-XTR-9836322 p-PKR dimer phosphorylates MKK6 IEA Xenopus tropicalis 30616 R-XTR-9836362 https://reactome.org/PathwayBrowser/#/R-XTR-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Xenopus tropicalis 30616 R-XTR-9836383 https://reactome.org/PathwayBrowser/#/R-XTR-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Xenopus tropicalis 30616 R-XTR-9836435 https://reactome.org/PathwayBrowser/#/R-XTR-9836435 p-PKR dimer phosphorylates SNCA IEA Xenopus tropicalis 30616 R-XTR-9837337 https://reactome.org/PathwayBrowser/#/R-XTR-9837337 DCAKD phosphorylates DP-CoA IEA Xenopus tropicalis 30616 R-XTR-9838289 https://reactome.org/PathwayBrowser/#/R-XTR-9838289 CLPXP degrades mitochondrial matrix proteins IEA Xenopus tropicalis 30616 R-XTR-9838321 https://reactome.org/PathwayBrowser/#/R-XTR-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Xenopus tropicalis 30616 R-XTR-9839059 https://reactome.org/PathwayBrowser/#/R-XTR-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Xenopus tropicalis 30616 R-XTR-9839105 https://reactome.org/PathwayBrowser/#/R-XTR-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Xenopus tropicalis 30616 R-XTR-9839113 https://reactome.org/PathwayBrowser/#/R-XTR-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Xenopus tropicalis 30616 R-XTR-9840564 https://reactome.org/PathwayBrowser/#/R-XTR-9840564 OMA1 hydrolyzes YME1L1 IEA Xenopus tropicalis 30616 R-XTR-9842648 https://reactome.org/PathwayBrowser/#/R-XTR-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 IEA Xenopus tropicalis 30616 R-XTR-9842651 https://reactome.org/PathwayBrowser/#/R-XTR-9842651 Active LTK receptor phosphorylates SHC1 IEA Xenopus tropicalis 30616 R-XTR-9842666 https://reactome.org/PathwayBrowser/#/R-XTR-9842666 Active LTK phosphorylates IRS1 IEA Xenopus tropicalis 30616 R-XTR-9843721 https://reactome.org/PathwayBrowser/#/R-XTR-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Xenopus tropicalis 30616 R-XTR-994137 https://reactome.org/PathwayBrowser/#/R-XTR-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Xenopus tropicalis 30616 R-XTR-994140 https://reactome.org/PathwayBrowser/#/R-XTR-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Xenopus tropicalis 30623 R-HSA-9640316 https://reactome.org/PathwayBrowser/#/R-HSA-9640316 DeHA hydrolyses to threonate and oxalate TAS Homo sapiens 30623 R-HSA-9640321 https://reactome.org/PathwayBrowser/#/R-HSA-9640321 2,3-DKG hydrolyses to ERU and oxalate TAS Homo sapiens 30725 R-BTA-156526 https://reactome.org/PathwayBrowser/#/R-BTA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Bos taurus 30725 R-BTA-176059 https://reactome.org/PathwayBrowser/#/R-BTA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Bos taurus 30725 R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 30725 R-BTA-5423653 https://reactome.org/PathwayBrowser/#/R-BTA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Bos taurus 30725 R-CEL-156526 https://reactome.org/PathwayBrowser/#/R-CEL-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Caenorhabditis elegans 30725 R-CFA-156526 https://reactome.org/PathwayBrowser/#/R-CFA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Canis familiaris 30725 R-CFA-176059 https://reactome.org/PathwayBrowser/#/R-CFA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Canis familiaris 30725 R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 30725 R-CFA-5423653 https://reactome.org/PathwayBrowser/#/R-CFA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Canis familiaris 30725 R-DDI-156526 https://reactome.org/PathwayBrowser/#/R-DDI-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Dictyostelium discoideum 30725 R-DDI-176059 https://reactome.org/PathwayBrowser/#/R-DDI-176059 GST trimers transfer GS from GSH to luminal substrates IEA Dictyostelium discoideum 30725 R-DDI-5423653 https://reactome.org/PathwayBrowser/#/R-DDI-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Dictyostelium discoideum 30725 R-DME-156526 https://reactome.org/PathwayBrowser/#/R-DME-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Drosophila melanogaster 30725 R-DME-176059 https://reactome.org/PathwayBrowser/#/R-DME-176059 GST trimers transfer GS from GSH to luminal substrates IEA Drosophila melanogaster 30725 R-DME-5423653 https://reactome.org/PathwayBrowser/#/R-DME-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Drosophila melanogaster 30725 R-DRE-156526 https://reactome.org/PathwayBrowser/#/R-DRE-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Danio rerio 30725 R-DRE-176059 https://reactome.org/PathwayBrowser/#/R-DRE-176059 GST trimers transfer GS from GSH to luminal substrates IEA Danio rerio 30725 R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 30725 R-DRE-5423653 https://reactome.org/PathwayBrowser/#/R-DRE-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Danio rerio 30725 R-GGA-156526 https://reactome.org/PathwayBrowser/#/R-GGA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Gallus gallus 30725 R-GGA-176059 https://reactome.org/PathwayBrowser/#/R-GGA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Gallus gallus 30725 R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 30725 R-GGA-5423653 https://reactome.org/PathwayBrowser/#/R-GGA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Gallus gallus 30725 R-HSA-156526 https://reactome.org/PathwayBrowser/#/R-HSA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO TAS Homo sapiens 30725 R-HSA-176059 https://reactome.org/PathwayBrowser/#/R-HSA-176059 GST trimers transfer GS from GSH to luminal substrates TAS Homo sapiens 30725 R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 30725 R-HSA-5423632 https://reactome.org/PathwayBrowser/#/R-HSA-5423632 AFXBO binds DNA TAS Homo sapiens 30725 R-HSA-5423653 https://reactome.org/PathwayBrowser/#/R-HSA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO TAS Homo sapiens 30725 R-HSA-5423656 https://reactome.org/PathwayBrowser/#/R-HSA-5423656 AFXBO hydrolyses non-enzymatically to AFBDHD TAS Homo sapiens 30725 R-HSA-5423728 https://reactome.org/PathwayBrowser/#/R-HSA-5423728 AFXBO translocates from cytosol to nucleoplasm TAS Homo sapiens 30725 R-MMU-156526 https://reactome.org/PathwayBrowser/#/R-MMU-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Mus musculus 30725 R-MMU-176059 https://reactome.org/PathwayBrowser/#/R-MMU-176059 GST trimers transfer GS from GSH to luminal substrates IEA Mus musculus 30725 R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 30725 R-MMU-5423653 https://reactome.org/PathwayBrowser/#/R-MMU-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Mus musculus 30725 R-RNO-156526 https://reactome.org/PathwayBrowser/#/R-RNO-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Rattus norvegicus 30725 R-RNO-176059 https://reactome.org/PathwayBrowser/#/R-RNO-176059 GST trimers transfer GS from GSH to luminal substrates IEA Rattus norvegicus 30725 R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 30725 R-RNO-5423653 https://reactome.org/PathwayBrowser/#/R-RNO-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Rattus norvegicus 30725 R-SSC-156526 https://reactome.org/PathwayBrowser/#/R-SSC-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Sus scrofa 30725 R-SSC-176059 https://reactome.org/PathwayBrowser/#/R-SSC-176059 GST trimers transfer GS from GSH to luminal substrates IEA Sus scrofa 30725 R-SSC-213175 https://reactome.org/PathwayBrowser/#/R-SSC-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Sus scrofa 30725 R-SSC-5423653 https://reactome.org/PathwayBrowser/#/R-SSC-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Sus scrofa 30725 R-XTR-156526 https://reactome.org/PathwayBrowser/#/R-XTR-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 30725 R-XTR-176059 https://reactome.org/PathwayBrowser/#/R-XTR-176059 GST trimers transfer GS from GSH to luminal substrates IEA Xenopus tropicalis 30725 R-XTR-213175 https://reactome.org/PathwayBrowser/#/R-XTR-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 30725 R-XTR-5423653 https://reactome.org/PathwayBrowser/#/R-XTR-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Xenopus tropicalis 30737 R-BTA-76434 https://reactome.org/PathwayBrowser/#/R-BTA-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Bos taurus 30737 R-CEL-76434 https://reactome.org/PathwayBrowser/#/R-CEL-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Caenorhabditis elegans 30737 R-CFA-76434 https://reactome.org/PathwayBrowser/#/R-CFA-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Canis familiaris 30737 R-DDI-76434 https://reactome.org/PathwayBrowser/#/R-DDI-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Dictyostelium discoideum 30737 R-DME-76434 https://reactome.org/PathwayBrowser/#/R-DME-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Drosophila melanogaster 30737 R-DRE-76434 https://reactome.org/PathwayBrowser/#/R-DRE-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Danio rerio 30737 R-GGA-76434 https://reactome.org/PathwayBrowser/#/R-GGA-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Gallus gallus 30737 R-HSA-76434 https://reactome.org/PathwayBrowser/#/R-HSA-76434 Dehalogenation of carbon tetrachloride to form a free radical TAS Homo sapiens 30737 R-MMU-76434 https://reactome.org/PathwayBrowser/#/R-MMU-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Mus musculus 30737 R-RNO-76434 https://reactome.org/PathwayBrowser/#/R-RNO-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Rattus norvegicus 30737 R-SSC-76434 https://reactome.org/PathwayBrowser/#/R-SSC-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Sus scrofa 30737 R-XTR-76434 https://reactome.org/PathwayBrowser/#/R-XTR-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Xenopus tropicalis 30746 R-BTA-159443 https://reactome.org/PathwayBrowser/#/R-BTA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Bos taurus 30746 R-CFA-159443 https://reactome.org/PathwayBrowser/#/R-CFA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 30746 R-DRE-159443 https://reactome.org/PathwayBrowser/#/R-DRE-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Danio rerio 30746 R-GGA-159443 https://reactome.org/PathwayBrowser/#/R-GGA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 30746 R-HSA-159443 https://reactome.org/PathwayBrowser/#/R-HSA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 30746 R-MMU-159443 https://reactome.org/PathwayBrowser/#/R-MMU-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Mus musculus 30746 R-RNO-159443 https://reactome.org/PathwayBrowser/#/R-RNO-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 30746 R-SSC-159443 https://reactome.org/PathwayBrowser/#/R-SSC-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 30746 R-XTR-159443 https://reactome.org/PathwayBrowser/#/R-XTR-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 30753 R-BTA-174963 https://reactome.org/PathwayBrowser/#/R-BTA-174963 NAT1 acetylation IEA Bos taurus 30753 R-DRE-174963 https://reactome.org/PathwayBrowser/#/R-DRE-174963 NAT1 acetylation IEA Danio rerio 30753 R-GGA-174963 https://reactome.org/PathwayBrowser/#/R-GGA-174963 NAT1 acetylation IEA Gallus gallus 30753 R-HSA-174963 https://reactome.org/PathwayBrowser/#/R-HSA-174963 NAT1 acetylation TAS Homo sapiens 30753 R-MMU-174963 https://reactome.org/PathwayBrowser/#/R-MMU-174963 NAT1 acetylation IEA Mus musculus 30753 R-RNO-174963 https://reactome.org/PathwayBrowser/#/R-RNO-174963 NAT1 acetylation IEA Rattus norvegicus 30753 R-SSC-174963 https://reactome.org/PathwayBrowser/#/R-SSC-174963 NAT1 acetylation IEA Sus scrofa 30762 R-BTA-159567 https://reactome.org/PathwayBrowser/#/R-BTA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Bos taurus 30762 R-BTA-2314678 https://reactome.org/PathwayBrowser/#/R-BTA-2314678 ASA- acetylates PTGS1 IEA Bos taurus 30762 R-BTA-2314686 https://reactome.org/PathwayBrowser/#/R-BTA-2314686 ASA- acetylates PTGS2 IEA Bos taurus 30762 R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 30762 R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 30762 R-BTA-9749583 https://reactome.org/PathwayBrowser/#/R-BTA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Bos taurus 30762 R-BTA-9749590 https://reactome.org/PathwayBrowser/#/R-BTA-9749590 ASA- acetylates ALB IEA Bos taurus 30762 R-BTA-9749609 https://reactome.org/PathwayBrowser/#/R-BTA-9749609 BCHE hydrolyzes ASA- IEA Bos taurus 30762 R-BTA-9749647 https://reactome.org/PathwayBrowser/#/R-BTA-9749647 CES2 hydrolyzes ASA- IEA Bos taurus 30762 R-BTA-9749792 https://reactome.org/PathwayBrowser/#/R-BTA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Bos taurus 30762 R-BTA-9749986 https://reactome.org/PathwayBrowser/#/R-BTA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Bos taurus 30762 R-BTA-9750016 https://reactome.org/PathwayBrowser/#/R-BTA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Bos taurus 30762 R-BTA-9750666 https://reactome.org/PathwayBrowser/#/R-BTA-9750666 ALB binds ST IEA Bos taurus 30762 R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 30762 R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 30762 R-CEL-9749583 https://reactome.org/PathwayBrowser/#/R-CEL-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Caenorhabditis elegans 30762 R-CEL-9749609 https://reactome.org/PathwayBrowser/#/R-CEL-9749609 BCHE hydrolyzes ASA- IEA Caenorhabditis elegans 30762 R-CEL-9749647 https://reactome.org/PathwayBrowser/#/R-CEL-9749647 CES2 hydrolyzes ASA- IEA Caenorhabditis elegans 30762 R-CEL-9749792 https://reactome.org/PathwayBrowser/#/R-CEL-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Caenorhabditis elegans 30762 R-CEL-9749986 https://reactome.org/PathwayBrowser/#/R-CEL-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Caenorhabditis elegans 30762 R-CEL-9750016 https://reactome.org/PathwayBrowser/#/R-CEL-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Caenorhabditis elegans 30762 R-CFA-159567 https://reactome.org/PathwayBrowser/#/R-CFA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Canis familiaris 30762 R-CFA-2314678 https://reactome.org/PathwayBrowser/#/R-CFA-2314678 ASA- acetylates PTGS1 IEA Canis familiaris 30762 R-CFA-2314686 https://reactome.org/PathwayBrowser/#/R-CFA-2314686 ASA- acetylates PTGS2 IEA Canis familiaris 30762 R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 30762 R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 30762 R-CFA-9749590 https://reactome.org/PathwayBrowser/#/R-CFA-9749590 ASA- acetylates ALB IEA Canis familiaris 30762 R-CFA-9749609 https://reactome.org/PathwayBrowser/#/R-CFA-9749609 BCHE hydrolyzes ASA- IEA Canis familiaris 30762 R-CFA-9749647 https://reactome.org/PathwayBrowser/#/R-CFA-9749647 CES2 hydrolyzes ASA- IEA Canis familiaris 30762 R-CFA-9749792 https://reactome.org/PathwayBrowser/#/R-CFA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Canis familiaris 30762 R-CFA-9749986 https://reactome.org/PathwayBrowser/#/R-CFA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Canis familiaris 30762 R-CFA-9750016 https://reactome.org/PathwayBrowser/#/R-CFA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Canis familiaris 30762 R-CFA-9750666 https://reactome.org/PathwayBrowser/#/R-CFA-9750666 ALB binds ST IEA Canis familiaris 30762 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 30762 R-DDI-9749647 https://reactome.org/PathwayBrowser/#/R-DDI-9749647 CES2 hydrolyzes ASA- IEA Dictyostelium discoideum 30762 R-DDI-9749792 https://reactome.org/PathwayBrowser/#/R-DDI-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Dictyostelium discoideum 30762 R-DDI-9749977 https://reactome.org/PathwayBrowser/#/R-DDI-9749977 UGT1A6 glucuronates ST IEA Dictyostelium discoideum 30762 R-DDI-9749986 https://reactome.org/PathwayBrowser/#/R-DDI-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Dictyostelium discoideum 30762 R-DDI-9750016 https://reactome.org/PathwayBrowser/#/R-DDI-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Dictyostelium discoideum 30762 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 30762 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 30762 R-DME-9749583 https://reactome.org/PathwayBrowser/#/R-DME-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Drosophila melanogaster 30762 R-DME-9749609 https://reactome.org/PathwayBrowser/#/R-DME-9749609 BCHE hydrolyzes ASA- IEA Drosophila melanogaster 30762 R-DME-9749647 https://reactome.org/PathwayBrowser/#/R-DME-9749647 CES2 hydrolyzes ASA- IEA Drosophila melanogaster 30762 R-DME-9749792 https://reactome.org/PathwayBrowser/#/R-DME-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Drosophila melanogaster 30762 R-DME-9749986 https://reactome.org/PathwayBrowser/#/R-DME-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Drosophila melanogaster 30762 R-DME-9750016 https://reactome.org/PathwayBrowser/#/R-DME-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Drosophila melanogaster 30762 R-DRE-159567 https://reactome.org/PathwayBrowser/#/R-DRE-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Danio rerio 30762 R-DRE-2314678 https://reactome.org/PathwayBrowser/#/R-DRE-2314678 ASA- acetylates PTGS1 IEA Danio rerio 30762 R-DRE-2314686 https://reactome.org/PathwayBrowser/#/R-DRE-2314686 ASA- acetylates PTGS2 IEA Danio rerio 30762 R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 30762 R-DRE-9749583 https://reactome.org/PathwayBrowser/#/R-DRE-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Danio rerio 30762 R-DRE-9749647 https://reactome.org/PathwayBrowser/#/R-DRE-9749647 CES2 hydrolyzes ASA- IEA Danio rerio 30762 R-DRE-9749792 https://reactome.org/PathwayBrowser/#/R-DRE-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Danio rerio 30762 R-DRE-9749986 https://reactome.org/PathwayBrowser/#/R-DRE-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Danio rerio 30762 R-DRE-9750016 https://reactome.org/PathwayBrowser/#/R-DRE-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Danio rerio 30762 R-GGA-159567 https://reactome.org/PathwayBrowser/#/R-GGA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Gallus gallus 30762 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 30762 R-GGA-2314678 https://reactome.org/PathwayBrowser/#/R-GGA-2314678 ASA- acetylates PTGS1 IEA Gallus gallus 30762 R-GGA-2314686 https://reactome.org/PathwayBrowser/#/R-GGA-2314686 ASA- acetylates PTGS2 IEA Gallus gallus 30762 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 30762 R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 30762 R-GGA-9749583 https://reactome.org/PathwayBrowser/#/R-GGA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Gallus gallus 30762 R-GGA-9749590 https://reactome.org/PathwayBrowser/#/R-GGA-9749590 ASA- acetylates ALB IEA Gallus gallus 30762 R-GGA-9749609 https://reactome.org/PathwayBrowser/#/R-GGA-9749609 BCHE hydrolyzes ASA- IEA Gallus gallus 30762 R-GGA-9749647 https://reactome.org/PathwayBrowser/#/R-GGA-9749647 CES2 hydrolyzes ASA- IEA Gallus gallus 30762 R-GGA-9749792 https://reactome.org/PathwayBrowser/#/R-GGA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Gallus gallus 30762 R-GGA-9749977 https://reactome.org/PathwayBrowser/#/R-GGA-9749977 UGT1A6 glucuronates ST IEA Gallus gallus 30762 R-GGA-9749986 https://reactome.org/PathwayBrowser/#/R-GGA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Gallus gallus 30762 R-GGA-9750016 https://reactome.org/PathwayBrowser/#/R-GGA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Gallus gallus 30762 R-GGA-9750666 https://reactome.org/PathwayBrowser/#/R-GGA-9750666 ALB binds ST IEA Gallus gallus 30762 R-HSA-159567 https://reactome.org/PathwayBrowser/#/R-HSA-159567 ACSM2B-like proteins transform ST to ST-CoA TAS Homo sapiens 30762 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 30762 R-HSA-2314678 https://reactome.org/PathwayBrowser/#/R-HSA-2314678 ASA- acetylates PTGS1 TAS Homo sapiens 30762 R-HSA-2314686 https://reactome.org/PathwayBrowser/#/R-HSA-2314686 ASA- acetylates PTGS2 TAS Homo sapiens 30762 R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 30762 R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 30762 R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 30762 R-HSA-9749583 https://reactome.org/PathwayBrowser/#/R-HSA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes TAS Homo sapiens 30762 R-HSA-9749590 https://reactome.org/PathwayBrowser/#/R-HSA-9749590 ASA- acetylates ALB TAS Homo sapiens 30762 R-HSA-9749609 https://reactome.org/PathwayBrowser/#/R-HSA-9749609 BCHE hydrolyzes ASA- TAS Homo sapiens 30762 R-HSA-9749647 https://reactome.org/PathwayBrowser/#/R-HSA-9749647 CES2 hydrolyzes ASA- TAS Homo sapiens 30762 R-HSA-9749792 https://reactome.org/PathwayBrowser/#/R-HSA-9749792 CES1,CES2 hydrolyze ASA- to ST TAS Homo sapiens 30762 R-HSA-9749977 https://reactome.org/PathwayBrowser/#/R-HSA-9749977 UGT1A6 glucuronates ST TAS Homo sapiens 30762 R-HSA-9749986 https://reactome.org/PathwayBrowser/#/R-HSA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA TAS Homo sapiens 30762 R-HSA-9750016 https://reactome.org/PathwayBrowser/#/R-HSA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA TAS Homo sapiens 30762 R-HSA-9750666 https://reactome.org/PathwayBrowser/#/R-HSA-9750666 ALB binds ST TAS Homo sapiens 30762 R-HSA-9757445 https://reactome.org/PathwayBrowser/#/R-HSA-9757445 ST translocates from ER lumen to cytosol of GI cells TAS Homo sapiens 30762 R-HSA-9757448 https://reactome.org/PathwayBrowser/#/R-HSA-9757448 ST translocates from cytosol to extracellular region TAS Homo sapiens 30762 R-HSA-9757451 https://reactome.org/PathwayBrowser/#/R-HSA-9757451 ASA-,ST translocate from cytosol to ER lumen of hepatocytes TAS Homo sapiens 30762 R-HSA-9757454 https://reactome.org/PathwayBrowser/#/R-HSA-9757454 ST translocates from cytosol to mitochondrial matrix of hepatocytes TAS Homo sapiens 30762 R-HSA-9757462 https://reactome.org/PathwayBrowser/#/R-HSA-9757462 Hydroxyl radicals oxidize ST to 2,3-DHBA TAS Homo sapiens 30762 R-MMU-159567 https://reactome.org/PathwayBrowser/#/R-MMU-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Mus musculus 30762 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 30762 R-MMU-2314678 https://reactome.org/PathwayBrowser/#/R-MMU-2314678 ASA- acetylates PTGS1 IEA Mus musculus 30762 R-MMU-2314686 https://reactome.org/PathwayBrowser/#/R-MMU-2314686 ASA- acetylates PTGS2 IEA Mus musculus 30762 R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 30762 R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 30762 R-MMU-9749583 https://reactome.org/PathwayBrowser/#/R-MMU-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Mus musculus 30762 R-MMU-9749590 https://reactome.org/PathwayBrowser/#/R-MMU-9749590 ASA- acetylates ALB IEA Mus musculus 30762 R-MMU-9749609 https://reactome.org/PathwayBrowser/#/R-MMU-9749609 BCHE hydrolyzes ASA- IEA Mus musculus 30762 R-MMU-9749647 https://reactome.org/PathwayBrowser/#/R-MMU-9749647 CES2 hydrolyzes ASA- IEA Mus musculus 30762 R-MMU-9749792 https://reactome.org/PathwayBrowser/#/R-MMU-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Mus musculus 30762 R-MMU-9749977 https://reactome.org/PathwayBrowser/#/R-MMU-9749977 UGT1A6 glucuronates ST IEA Mus musculus 30762 R-MMU-9749986 https://reactome.org/PathwayBrowser/#/R-MMU-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Mus musculus 30762 R-MMU-9750016 https://reactome.org/PathwayBrowser/#/R-MMU-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Mus musculus 30762 R-MMU-9750666 https://reactome.org/PathwayBrowser/#/R-MMU-9750666 ALB binds ST IEA Mus musculus 30762 R-RNO-159567 https://reactome.org/PathwayBrowser/#/R-RNO-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Rattus norvegicus 30762 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 30762 R-RNO-2314678 https://reactome.org/PathwayBrowser/#/R-RNO-2314678 ASA- acetylates PTGS1 IEA Rattus norvegicus 30762 R-RNO-2314686 https://reactome.org/PathwayBrowser/#/R-RNO-2314686 ASA- acetylates PTGS2 IEA Rattus norvegicus 30762 R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 30762 R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 30762 R-RNO-9749583 https://reactome.org/PathwayBrowser/#/R-RNO-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Rattus norvegicus 30762 R-RNO-9749590 https://reactome.org/PathwayBrowser/#/R-RNO-9749590 ASA- acetylates ALB IEA Rattus norvegicus 30762 R-RNO-9749609 https://reactome.org/PathwayBrowser/#/R-RNO-9749609 BCHE hydrolyzes ASA- IEA Rattus norvegicus 30762 R-RNO-9749647 https://reactome.org/PathwayBrowser/#/R-RNO-9749647 CES2 hydrolyzes ASA- IEA Rattus norvegicus 30762 R-RNO-9749792 https://reactome.org/PathwayBrowser/#/R-RNO-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Rattus norvegicus 30762 R-RNO-9749977 https://reactome.org/PathwayBrowser/#/R-RNO-9749977 UGT1A6 glucuronates ST IEA Rattus norvegicus 30762 R-RNO-9749986 https://reactome.org/PathwayBrowser/#/R-RNO-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Rattus norvegicus 30762 R-RNO-9750016 https://reactome.org/PathwayBrowser/#/R-RNO-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Rattus norvegicus 30762 R-RNO-9750666 https://reactome.org/PathwayBrowser/#/R-RNO-9750666 ALB binds ST IEA Rattus norvegicus 30762 R-SSC-159567 https://reactome.org/PathwayBrowser/#/R-SSC-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Sus scrofa 30762 R-SSC-2314678 https://reactome.org/PathwayBrowser/#/R-SSC-2314678 ASA- acetylates PTGS1 IEA Sus scrofa 30762 R-SSC-2314686 https://reactome.org/PathwayBrowser/#/R-SSC-2314686 ASA- acetylates PTGS2 IEA Sus scrofa 30762 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 30762 R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 30762 R-SSC-9749583 https://reactome.org/PathwayBrowser/#/R-SSC-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Sus scrofa 30762 R-SSC-9749590 https://reactome.org/PathwayBrowser/#/R-SSC-9749590 ASA- acetylates ALB IEA Sus scrofa 30762 R-SSC-9749792 https://reactome.org/PathwayBrowser/#/R-SSC-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Sus scrofa 30762 R-SSC-9749986 https://reactome.org/PathwayBrowser/#/R-SSC-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Sus scrofa 30762 R-SSC-9750016 https://reactome.org/PathwayBrowser/#/R-SSC-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Sus scrofa 30762 R-SSC-9750666 https://reactome.org/PathwayBrowser/#/R-SSC-9750666 ALB binds ST IEA Sus scrofa 30762 R-XTR-159567 https://reactome.org/PathwayBrowser/#/R-XTR-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Xenopus tropicalis 30762 R-XTR-2314678 https://reactome.org/PathwayBrowser/#/R-XTR-2314678 ASA- acetylates PTGS1 IEA Xenopus tropicalis 30762 R-XTR-2314686 https://reactome.org/PathwayBrowser/#/R-XTR-2314686 ASA- acetylates PTGS2 IEA Xenopus tropicalis 30762 R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 30762 R-XTR-9749590 https://reactome.org/PathwayBrowser/#/R-XTR-9749590 ASA- acetylates ALB IEA Xenopus tropicalis 30762 R-XTR-9749609 https://reactome.org/PathwayBrowser/#/R-XTR-9749609 BCHE hydrolyzes ASA- IEA Xenopus tropicalis 30762 R-XTR-9749792 https://reactome.org/PathwayBrowser/#/R-XTR-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Xenopus tropicalis 30762 R-XTR-9749986 https://reactome.org/PathwayBrowser/#/R-XTR-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Xenopus tropicalis 30762 R-XTR-9750016 https://reactome.org/PathwayBrowser/#/R-XTR-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Xenopus tropicalis 30762 R-XTR-9750666 https://reactome.org/PathwayBrowser/#/R-XTR-9750666 ALB binds ST IEA Xenopus tropicalis 30768 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 30768 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Bos taurus 30768 R-BTA-444047 https://reactome.org/PathwayBrowser/#/R-BTA-444047 Receptor FFAR3 binds carboxylates IEA Bos taurus 30768 R-BTA-444171 https://reactome.org/PathwayBrowser/#/R-BTA-444171 Receptor FFAR2 binds carboxylates IEA Bos taurus 30768 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 30768 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 30768 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 30768 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Caenorhabditis elegans 30768 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 30768 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 30768 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Canis familiaris 30768 R-CFA-444047 https://reactome.org/PathwayBrowser/#/R-CFA-444047 Receptor FFAR3 binds carboxylates IEA Canis familiaris 30768 R-CFA-444171 https://reactome.org/PathwayBrowser/#/R-CFA-444171 Receptor FFAR2 binds carboxylates IEA Canis familiaris 30768 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 30768 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 30768 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 30768 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Drosophila melanogaster 30768 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 30768 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 30768 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Danio rerio 30768 R-DRE-444047 https://reactome.org/PathwayBrowser/#/R-DRE-444047 Receptor FFAR3 binds carboxylates IEA Danio rerio 30768 R-DRE-444171 https://reactome.org/PathwayBrowser/#/R-DRE-444171 Receptor FFAR2 binds carboxylates IEA Danio rerio 30768 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 30768 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 30768 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Gallus gallus 30768 R-GGA-444171 https://reactome.org/PathwayBrowser/#/R-GGA-444171 Receptor FFAR2 binds carboxylates IEA Gallus gallus 30768 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 30768 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 30768 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 30768 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 30768 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol TAS Homo sapiens 30768 R-HSA-444047 https://reactome.org/PathwayBrowser/#/R-HSA-444047 Receptor FFAR3 binds carboxylates TAS Homo sapiens 30768 R-HSA-444171 https://reactome.org/PathwayBrowser/#/R-HSA-444171 Receptor FFAR2 binds carboxylates TAS Homo sapiens 30768 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 30768 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 30768 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 30768 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 30768 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 30768 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 30768 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Mus musculus 30768 R-MMU-444047 https://reactome.org/PathwayBrowser/#/R-MMU-444047 Receptor FFAR3 binds carboxylates IEA Mus musculus 30768 R-MMU-444171 https://reactome.org/PathwayBrowser/#/R-MMU-444171 Receptor FFAR2 binds carboxylates IEA Mus musculus 30768 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 30768 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 30768 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 30768 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 30768 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Rattus norvegicus 30768 R-RNO-444047 https://reactome.org/PathwayBrowser/#/R-RNO-444047 Receptor FFAR3 binds carboxylates IEA Rattus norvegicus 30768 R-RNO-444171 https://reactome.org/PathwayBrowser/#/R-RNO-444171 Receptor FFAR2 binds carboxylates IEA Rattus norvegicus 30768 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 30768 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Sus scrofa 30768 R-SSC-444047 https://reactome.org/PathwayBrowser/#/R-SSC-444047 Receptor FFAR3 binds carboxylates IEA Sus scrofa 30768 R-SSC-444171 https://reactome.org/PathwayBrowser/#/R-SSC-444171 Receptor FFAR2 binds carboxylates IEA Sus scrofa 30768 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 30768 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 30768 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 30768 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Xenopus tropicalis 30768 R-XTR-444171 https://reactome.org/PathwayBrowser/#/R-XTR-444171 Receptor FFAR2 binds carboxylates IEA Xenopus tropicalis 30768 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 30768 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 30769 R-BTA-200555 https://reactome.org/PathwayBrowser/#/R-BTA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Bos taurus 30769 R-BTA-433104 https://reactome.org/PathwayBrowser/#/R-BTA-433104 NACT co-transports trivalent citrate and a sodium ion IEA Bos taurus 30769 R-BTA-433131 https://reactome.org/PathwayBrowser/#/R-BTA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Bos taurus 30769 R-BTA-5690911 https://reactome.org/PathwayBrowser/#/R-BTA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Bos taurus 30769 R-BTA-70467 https://reactome.org/PathwayBrowser/#/R-BTA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Bos taurus 30769 R-BTA-75848 https://reactome.org/PathwayBrowser/#/R-BTA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Bos taurus 30769 R-BTA-75849 https://reactome.org/PathwayBrowser/#/R-BTA-75849 SLC25A1 exchanges CIT and MAL IEA Bos taurus 30769 R-BTA-75851 https://reactome.org/PathwayBrowser/#/R-BTA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 30769 R-BTA-8876889 https://reactome.org/PathwayBrowser/#/R-BTA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 30769 R-CEL-200555 https://reactome.org/PathwayBrowser/#/R-CEL-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Caenorhabditis elegans 30769 R-CEL-433104 https://reactome.org/PathwayBrowser/#/R-CEL-433104 NACT co-transports trivalent citrate and a sodium ion IEA Caenorhabditis elegans 30769 R-CEL-433131 https://reactome.org/PathwayBrowser/#/R-CEL-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Caenorhabditis elegans 30769 R-CEL-5690911 https://reactome.org/PathwayBrowser/#/R-CEL-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Caenorhabditis elegans 30769 R-CEL-70467 https://reactome.org/PathwayBrowser/#/R-CEL-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Caenorhabditis elegans 30769 R-CEL-75848 https://reactome.org/PathwayBrowser/#/R-CEL-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Caenorhabditis elegans 30769 R-CEL-75849 https://reactome.org/PathwayBrowser/#/R-CEL-75849 SLC25A1 exchanges CIT and MAL IEA Caenorhabditis elegans 30769 R-CEL-75851 https://reactome.org/PathwayBrowser/#/R-CEL-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 30769 R-CEL-8876889 https://reactome.org/PathwayBrowser/#/R-CEL-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 30769 R-CFA-200555 https://reactome.org/PathwayBrowser/#/R-CFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Canis familiaris 30769 R-CFA-433104 https://reactome.org/PathwayBrowser/#/R-CFA-433104 NACT co-transports trivalent citrate and a sodium ion IEA Canis familiaris 30769 R-CFA-433131 https://reactome.org/PathwayBrowser/#/R-CFA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Canis familiaris 30769 R-CFA-5690911 https://reactome.org/PathwayBrowser/#/R-CFA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Canis familiaris 30769 R-CFA-70467 https://reactome.org/PathwayBrowser/#/R-CFA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Canis familiaris 30769 R-CFA-75848 https://reactome.org/PathwayBrowser/#/R-CFA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Canis familiaris 30769 R-CFA-75849 https://reactome.org/PathwayBrowser/#/R-CFA-75849 SLC25A1 exchanges CIT and MAL IEA Canis familiaris 30769 R-CFA-75851 https://reactome.org/PathwayBrowser/#/R-CFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 30769 R-CFA-8876889 https://reactome.org/PathwayBrowser/#/R-CFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 30769 R-DDI-200555 https://reactome.org/PathwayBrowser/#/R-DDI-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Dictyostelium discoideum 30769 R-DDI-5690911 https://reactome.org/PathwayBrowser/#/R-DDI-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Dictyostelium discoideum 30769 R-DDI-75848 https://reactome.org/PathwayBrowser/#/R-DDI-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Dictyostelium discoideum 30769 R-DDI-75851 https://reactome.org/PathwayBrowser/#/R-DDI-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 30769 R-DDI-8876889 https://reactome.org/PathwayBrowser/#/R-DDI-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 30769 R-DME-200555 https://reactome.org/PathwayBrowser/#/R-DME-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Drosophila melanogaster 30769 R-DME-433104 https://reactome.org/PathwayBrowser/#/R-DME-433104 NACT co-transports trivalent citrate and a sodium ion IEA Drosophila melanogaster 30769 R-DME-433131 https://reactome.org/PathwayBrowser/#/R-DME-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Drosophila melanogaster 30769 R-DME-5690911 https://reactome.org/PathwayBrowser/#/R-DME-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Drosophila melanogaster 30769 R-DME-70467 https://reactome.org/PathwayBrowser/#/R-DME-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Drosophila melanogaster 30769 R-DME-75848 https://reactome.org/PathwayBrowser/#/R-DME-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Drosophila melanogaster 30769 R-DME-75849 https://reactome.org/PathwayBrowser/#/R-DME-75849 SLC25A1 exchanges CIT and MAL IEA Drosophila melanogaster 30769 R-DME-75851 https://reactome.org/PathwayBrowser/#/R-DME-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 30769 R-DME-8876889 https://reactome.org/PathwayBrowser/#/R-DME-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 30769 R-DRE-433131 https://reactome.org/PathwayBrowser/#/R-DRE-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Danio rerio 30769 R-DRE-5690911 https://reactome.org/PathwayBrowser/#/R-DRE-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Danio rerio 30769 R-DRE-70467 https://reactome.org/PathwayBrowser/#/R-DRE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Danio rerio 30769 R-DRE-75848 https://reactome.org/PathwayBrowser/#/R-DRE-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Danio rerio 30769 R-DRE-75849 https://reactome.org/PathwayBrowser/#/R-DRE-75849 SLC25A1 exchanges CIT and MAL IEA Danio rerio 30769 R-GGA-200555 https://reactome.org/PathwayBrowser/#/R-GGA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Gallus gallus 30769 R-GGA-372723 https://reactome.org/PathwayBrowser/#/R-GGA-372723 phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] <=> phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix] IEA Gallus gallus 30769 R-GGA-433104 https://reactome.org/PathwayBrowser/#/R-GGA-433104 NACT co-transports trivalent citrate and a sodium ion IEA Gallus gallus 30769 R-GGA-433131 https://reactome.org/PathwayBrowser/#/R-GGA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Gallus gallus 30769 R-GGA-5690911 https://reactome.org/PathwayBrowser/#/R-GGA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Gallus gallus 30769 R-GGA-70467 https://reactome.org/PathwayBrowser/#/R-GGA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Gallus gallus 30769 R-GGA-75848 https://reactome.org/PathwayBrowser/#/R-GGA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Gallus gallus 30769 R-GGA-75849 https://reactome.org/PathwayBrowser/#/R-GGA-75849 SLC25A1 exchanges CIT and MAL IEA Gallus gallus 30769 R-GGA-75851 https://reactome.org/PathwayBrowser/#/R-GGA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Gallus gallus 30769 R-HSA-200555 https://reactome.org/PathwayBrowser/#/R-HSA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate TAS Homo sapiens 30769 R-HSA-433104 https://reactome.org/PathwayBrowser/#/R-HSA-433104 NACT co-transports trivalent citrate and a sodium ion TAS Homo sapiens 30769 R-HSA-433131 https://reactome.org/PathwayBrowser/#/R-HSA-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion TAS Homo sapiens 30769 R-HSA-5690911 https://reactome.org/PathwayBrowser/#/R-HSA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT TAS Homo sapiens 30769 R-HSA-70467 https://reactome.org/PathwayBrowser/#/R-HSA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP TAS Homo sapiens 30769 R-HSA-75848 https://reactome.org/PathwayBrowser/#/R-HSA-75848 ACLY tetramer transforms CIT to Ac-CoA TAS Homo sapiens 30769 R-HSA-75849 https://reactome.org/PathwayBrowser/#/R-HSA-75849 SLC25A1 exchanges CIT and MAL TAS Homo sapiens 30769 R-HSA-75851 https://reactome.org/PathwayBrowser/#/R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 30769 R-HSA-8876889 https://reactome.org/PathwayBrowser/#/R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 30769 R-HSA-9737111 https://reactome.org/PathwayBrowser/#/R-HSA-9737111 Protonated weak acid translocates across the plasma membrane IEA Homo sapiens 30769 R-MMU-200555 https://reactome.org/PathwayBrowser/#/R-MMU-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Mus musculus 30769 R-MMU-433104 https://reactome.org/PathwayBrowser/#/R-MMU-433104 NACT co-transports trivalent citrate and a sodium ion IEA Mus musculus 30769 R-MMU-433131 https://reactome.org/PathwayBrowser/#/R-MMU-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Mus musculus 30769 R-MMU-5690911 https://reactome.org/PathwayBrowser/#/R-MMU-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Mus musculus 30769 R-MMU-70467 https://reactome.org/PathwayBrowser/#/R-MMU-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Mus musculus 30769 R-MMU-75848 https://reactome.org/PathwayBrowser/#/R-MMU-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Mus musculus 30769 R-MMU-75849 https://reactome.org/PathwayBrowser/#/R-MMU-75849 SLC25A1 exchanges CIT and MAL IEA Mus musculus 30769 R-MMU-75851 https://reactome.org/PathwayBrowser/#/R-MMU-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 30769 R-MMU-8876889 https://reactome.org/PathwayBrowser/#/R-MMU-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 30769 R-MMU-9750040 https://reactome.org/PathwayBrowser/#/R-MMU-9750040 Protonated weak acid translocates across the plasma membrane TAS Mus musculus 30769 R-PFA-200555 https://reactome.org/PathwayBrowser/#/R-PFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Plasmodium falciparum 30769 R-PFA-5690911 https://reactome.org/PathwayBrowser/#/R-PFA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Plasmodium falciparum 30769 R-PFA-75851 https://reactome.org/PathwayBrowser/#/R-PFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 30769 R-PFA-8876889 https://reactome.org/PathwayBrowser/#/R-PFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 30769 R-RNO-200555 https://reactome.org/PathwayBrowser/#/R-RNO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Rattus norvegicus 30769 R-RNO-433104 https://reactome.org/PathwayBrowser/#/R-RNO-433104 NACT co-transports trivalent citrate and a sodium ion IEA Rattus norvegicus 30769 R-RNO-433131 https://reactome.org/PathwayBrowser/#/R-RNO-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Rattus norvegicus 30769 R-RNO-5690911 https://reactome.org/PathwayBrowser/#/R-RNO-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Rattus norvegicus 30769 R-RNO-70467 https://reactome.org/PathwayBrowser/#/R-RNO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Rattus norvegicus 30769 R-RNO-75848 https://reactome.org/PathwayBrowser/#/R-RNO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Rattus norvegicus 30769 R-RNO-75849 https://reactome.org/PathwayBrowser/#/R-RNO-75849 SLC25A1 exchanges CIT and MAL IEA Rattus norvegicus 30769 R-RNO-75851 https://reactome.org/PathwayBrowser/#/R-RNO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 30769 R-RNO-8876889 https://reactome.org/PathwayBrowser/#/R-RNO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 30769 R-RNO-9749957 https://reactome.org/PathwayBrowser/#/R-RNO-9749957 Protonated weak acid translocates across the plasma membrane TAS Rattus norvegicus 30769 R-SCE-200555 https://reactome.org/PathwayBrowser/#/R-SCE-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Saccharomyces cerevisiae 30769 R-SCE-70467 https://reactome.org/PathwayBrowser/#/R-SCE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 30769 R-SCE-75849 https://reactome.org/PathwayBrowser/#/R-SCE-75849 SLC25A1 exchanges CIT and MAL IEA Saccharomyces cerevisiae 30769 R-SCE-75851 https://reactome.org/PathwayBrowser/#/R-SCE-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 30769 R-SCE-8876889 https://reactome.org/PathwayBrowser/#/R-SCE-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 30769 R-SPO-200555 https://reactome.org/PathwayBrowser/#/R-SPO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Schizosaccharomyces pombe 30769 R-SPO-70467 https://reactome.org/PathwayBrowser/#/R-SPO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 30769 R-SPO-75848 https://reactome.org/PathwayBrowser/#/R-SPO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Schizosaccharomyces pombe 30769 R-SPO-75849 https://reactome.org/PathwayBrowser/#/R-SPO-75849 SLC25A1 exchanges CIT and MAL IEA Schizosaccharomyces pombe 30769 R-SPO-75851 https://reactome.org/PathwayBrowser/#/R-SPO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 30769 R-SPO-8876889 https://reactome.org/PathwayBrowser/#/R-SPO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 30769 R-SSC-200555 https://reactome.org/PathwayBrowser/#/R-SSC-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Sus scrofa 30769 R-SSC-433104 https://reactome.org/PathwayBrowser/#/R-SSC-433104 NACT co-transports trivalent citrate and a sodium ion IEA Sus scrofa 30769 R-SSC-433131 https://reactome.org/PathwayBrowser/#/R-SSC-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Sus scrofa 30769 R-SSC-5690911 https://reactome.org/PathwayBrowser/#/R-SSC-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Sus scrofa 30769 R-SSC-70467 https://reactome.org/PathwayBrowser/#/R-SSC-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Sus scrofa 30769 R-SSC-75848 https://reactome.org/PathwayBrowser/#/R-SSC-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Sus scrofa 30769 R-SSC-75849 https://reactome.org/PathwayBrowser/#/R-SSC-75849 SLC25A1 exchanges CIT and MAL IEA Sus scrofa 30769 R-SSC-75851 https://reactome.org/PathwayBrowser/#/R-SSC-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 30769 R-SSC-8876889 https://reactome.org/PathwayBrowser/#/R-SSC-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 30769 R-XTR-200555 https://reactome.org/PathwayBrowser/#/R-XTR-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Xenopus tropicalis 30769 R-XTR-433104 https://reactome.org/PathwayBrowser/#/R-XTR-433104 NACT co-transports trivalent citrate and a sodium ion IEA Xenopus tropicalis 30769 R-XTR-433131 https://reactome.org/PathwayBrowser/#/R-XTR-433131 NaDC1 co-transports dicarboxylic acids and a sodium ion IEA Xenopus tropicalis 30769 R-XTR-5690911 https://reactome.org/PathwayBrowser/#/R-XTR-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Xenopus tropicalis 30769 R-XTR-75848 https://reactome.org/PathwayBrowser/#/R-XTR-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Xenopus tropicalis 30769 R-XTR-75849 https://reactome.org/PathwayBrowser/#/R-XTR-75849 SLC25A1 exchanges CIT and MAL IEA Xenopus tropicalis 30769 R-XTR-75851 https://reactome.org/PathwayBrowser/#/R-XTR-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 30769 R-XTR-8876889 https://reactome.org/PathwayBrowser/#/R-XTR-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 30776 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 30776 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 30776 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 30776 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 30776 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 30776 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 30776 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 30776 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 30776 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 30805 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 30805 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 30805 R-BTA-400434 https://reactome.org/PathwayBrowser/#/R-BTA-400434 FFAR1 binds fatty acids IEA Bos taurus 30805 R-BTA-400509 https://reactome.org/PathwayBrowser/#/R-BTA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Bos taurus 30805 R-BTA-416530 https://reactome.org/PathwayBrowser/#/R-BTA-416530 FFAR1:FFAR1 ligands activate Gq IEA Bos taurus 30805 R-BTA-444202 https://reactome.org/PathwayBrowser/#/R-BTA-444202 Receptor FFAR1 binds free fatty acids IEA Bos taurus 30805 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 30805 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 30805 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 30805 R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 30805 R-BTA-879585 https://reactome.org/PathwayBrowser/#/R-BTA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Bos taurus 30805 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 30805 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 30805 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 30805 R-CEL-879585 https://reactome.org/PathwayBrowser/#/R-CEL-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Caenorhabditis elegans 30805 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 30805 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 30805 R-CFA-400434 https://reactome.org/PathwayBrowser/#/R-CFA-400434 FFAR1 binds fatty acids IEA Canis familiaris 30805 R-CFA-400509 https://reactome.org/PathwayBrowser/#/R-CFA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Canis familiaris 30805 R-CFA-416530 https://reactome.org/PathwayBrowser/#/R-CFA-416530 FFAR1:FFAR1 ligands activate Gq IEA Canis familiaris 30805 R-CFA-444202 https://reactome.org/PathwayBrowser/#/R-CFA-444202 Receptor FFAR1 binds free fatty acids IEA Canis familiaris 30805 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 30805 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 30805 R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 30805 R-CFA-879585 https://reactome.org/PathwayBrowser/#/R-CFA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Canis familiaris 30805 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 30805 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 30805 R-DME-879585 https://reactome.org/PathwayBrowser/#/R-DME-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Drosophila melanogaster 30805 R-DRE-879585 https://reactome.org/PathwayBrowser/#/R-DRE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Danio rerio 30805 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 30805 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 30805 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 30805 R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 30805 R-GGA-879585 https://reactome.org/PathwayBrowser/#/R-GGA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Gallus gallus 30805 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 30805 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 30805 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 30805 R-HSA-400434 https://reactome.org/PathwayBrowser/#/R-HSA-400434 FFAR1 binds fatty acids TAS Homo sapiens 30805 R-HSA-400509 https://reactome.org/PathwayBrowser/#/R-HSA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells TAS Homo sapiens 30805 R-HSA-416530 https://reactome.org/PathwayBrowser/#/R-HSA-416530 FFAR1:FFAR1 ligands activate Gq TAS Homo sapiens 30805 R-HSA-444202 https://reactome.org/PathwayBrowser/#/R-HSA-444202 Receptor FFAR1 binds free fatty acids TAS Homo sapiens 30805 R-HSA-5627891 https://reactome.org/PathwayBrowser/#/R-HSA-5627891 Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol TAS Homo sapiens 30805 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 30805 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 30805 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 30805 R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 30805 R-HSA-879585 https://reactome.org/PathwayBrowser/#/R-HSA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol TAS Homo sapiens 30805 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 30805 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 30805 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 30805 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 30805 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 30805 R-MMU-400434 https://reactome.org/PathwayBrowser/#/R-MMU-400434 FFAR1 binds fatty acids IEA Mus musculus 30805 R-MMU-400509 https://reactome.org/PathwayBrowser/#/R-MMU-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Mus musculus 30805 R-MMU-416530 https://reactome.org/PathwayBrowser/#/R-MMU-416530 FFAR1:FFAR1 ligands activate Gq IEA Mus musculus 30805 R-MMU-444202 https://reactome.org/PathwayBrowser/#/R-MMU-444202 Receptor FFAR1 binds free fatty acids IEA Mus musculus 30805 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 30805 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 30805 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 30805 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 30805 R-MMU-879585 https://reactome.org/PathwayBrowser/#/R-MMU-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Mus musculus 30805 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 30805 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 30805 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 30805 R-RNO-400434 https://reactome.org/PathwayBrowser/#/R-RNO-400434 FFAR1 binds fatty acids IEA Rattus norvegicus 30805 R-RNO-400509 https://reactome.org/PathwayBrowser/#/R-RNO-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Rattus norvegicus 30805 R-RNO-416530 https://reactome.org/PathwayBrowser/#/R-RNO-416530 FFAR1:FFAR1 ligands activate Gq IEA Rattus norvegicus 30805 R-RNO-444202 https://reactome.org/PathwayBrowser/#/R-RNO-444202 Receptor FFAR1 binds free fatty acids IEA Rattus norvegicus 30805 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 30805 R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 30805 R-RNO-879585 https://reactome.org/PathwayBrowser/#/R-RNO-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Rattus norvegicus 30805 R-SCE-879585 https://reactome.org/PathwayBrowser/#/R-SCE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Saccharomyces cerevisiae 30805 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 30805 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 30805 R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 30805 R-SSC-879585 https://reactome.org/PathwayBrowser/#/R-SSC-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Sus scrofa 30805 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 30805 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 30805 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 30805 R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 30805 R-XTR-879585 https://reactome.org/PathwayBrowser/#/R-XTR-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Xenopus tropicalis 30813 R-BTA-422017 https://reactome.org/PathwayBrowser/#/R-BTA-422017 Ghrelin O-acyltransferase decanoylates Proghrelin IEA Bos taurus 30813 R-BTA-879585 https://reactome.org/PathwayBrowser/#/R-BTA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Bos taurus 30813 R-CEL-879585 https://reactome.org/PathwayBrowser/#/R-CEL-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Caenorhabditis elegans 30813 R-CFA-422017 https://reactome.org/PathwayBrowser/#/R-CFA-422017 Ghrelin O-acyltransferase decanoylates Proghrelin IEA Canis familiaris 30813 R-CFA-879585 https://reactome.org/PathwayBrowser/#/R-CFA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Canis familiaris 30813 R-DME-879585 https://reactome.org/PathwayBrowser/#/R-DME-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Drosophila melanogaster 30813 R-DRE-422017 https://reactome.org/PathwayBrowser/#/R-DRE-422017 Ghrelin O-acyltransferase decanoylates Proghrelin IEA Danio rerio 30813 R-DRE-879585 https://reactome.org/PathwayBrowser/#/R-DRE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Danio rerio 30813 R-GGA-422017 https://reactome.org/PathwayBrowser/#/R-GGA-422017 Ghrelin O-acyltransferase decanoylates Proghrelin IEA Gallus gallus 30813 R-GGA-879585 https://reactome.org/PathwayBrowser/#/R-GGA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Gallus gallus 30813 R-HSA-422017 https://reactome.org/PathwayBrowser/#/R-HSA-422017 Ghrelin O-acyltransferase decanoylates Proghrelin TAS Homo sapiens 30813 R-HSA-5627891 https://reactome.org/PathwayBrowser/#/R-HSA-5627891 Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol TAS Homo sapiens 30813 R-HSA-5655955 https://reactome.org/PathwayBrowser/#/R-HSA-5655955 OLAH hydrolyzes decanoyl-FASN dimer to DECA and FASN dimer IEA Homo sapiens 30813 R-HSA-879585 https://reactome.org/PathwayBrowser/#/R-HSA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol TAS Homo sapiens 30813 R-MMU-422017 https://reactome.org/PathwayBrowser/#/R-MMU-422017 Ghrelin O-acyltransferase decanoylates Proghrelin IEA Mus musculus 30813 R-MMU-879585 https://reactome.org/PathwayBrowser/#/R-MMU-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Mus musculus 30813 R-RNO-422017 https://reactome.org/PathwayBrowser/#/R-RNO-422017 Ghrelin O-acyltransferase decanoylates Proghrelin IEA Rattus norvegicus 30813 R-RNO-5655945 https://reactome.org/PathwayBrowser/#/R-RNO-5655945 Olah hydrolyzes decanoyl-Fasn dimer to decanoate and Fasn dimer TAS Rattus norvegicus 30813 R-RNO-879585 https://reactome.org/PathwayBrowser/#/R-RNO-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Rattus norvegicus 30813 R-SCE-879585 https://reactome.org/PathwayBrowser/#/R-SCE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Saccharomyces cerevisiae 30813 R-SSC-422017 https://reactome.org/PathwayBrowser/#/R-SSC-422017 Ghrelin O-acyltransferase decanoylates Proghrelin IEA Sus scrofa 30813 R-SSC-879585 https://reactome.org/PathwayBrowser/#/R-SSC-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Sus scrofa 30813 R-XTR-879585 https://reactome.org/PathwayBrowser/#/R-XTR-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Xenopus tropicalis 30817 R-BTA-70899 https://reactome.org/PathwayBrowser/#/R-BTA-70899 histidine => urocanate + NH4+ IEA Bos taurus 30817 R-BTA-70903 https://reactome.org/PathwayBrowser/#/R-BTA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Bos taurus 30817 R-CEL-70899 https://reactome.org/PathwayBrowser/#/R-CEL-70899 histidine => urocanate + NH4+ IEA Caenorhabditis elegans 30817 R-CEL-70903 https://reactome.org/PathwayBrowser/#/R-CEL-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Caenorhabditis elegans 30817 R-CFA-70899 https://reactome.org/PathwayBrowser/#/R-CFA-70899 histidine => urocanate + NH4+ IEA Canis familiaris 30817 R-CFA-70903 https://reactome.org/PathwayBrowser/#/R-CFA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Canis familiaris 30817 R-DDI-70899 https://reactome.org/PathwayBrowser/#/R-DDI-70899 histidine => urocanate + NH4+ IEA Dictyostelium discoideum 30817 R-DDI-70903 https://reactome.org/PathwayBrowser/#/R-DDI-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Dictyostelium discoideum 30817 R-DRE-70899 https://reactome.org/PathwayBrowser/#/R-DRE-70899 histidine => urocanate + NH4+ IEA Danio rerio 30817 R-DRE-70903 https://reactome.org/PathwayBrowser/#/R-DRE-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Danio rerio 30817 R-GGA-70899 https://reactome.org/PathwayBrowser/#/R-GGA-70899 histidine => urocanate + NH4+ IEA Gallus gallus 30817 R-GGA-70903 https://reactome.org/PathwayBrowser/#/R-GGA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Gallus gallus 30817 R-HSA-70899 https://reactome.org/PathwayBrowser/#/R-HSA-70899 histidine => urocanate + NH4+ TAS Homo sapiens 30817 R-HSA-70903 https://reactome.org/PathwayBrowser/#/R-HSA-70903 urocanate + H2O => 4-imidazolone-5-propionate TAS Homo sapiens 30817 R-MMU-70899 https://reactome.org/PathwayBrowser/#/R-MMU-70899 histidine => urocanate + NH4+ IEA Mus musculus 30817 R-MMU-70903 https://reactome.org/PathwayBrowser/#/R-MMU-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Mus musculus 30817 R-RNO-70899 https://reactome.org/PathwayBrowser/#/R-RNO-70899 histidine => urocanate + NH4+ IEA Rattus norvegicus 30817 R-RNO-70903 https://reactome.org/PathwayBrowser/#/R-RNO-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Rattus norvegicus 30817 R-SSC-70899 https://reactome.org/PathwayBrowser/#/R-SSC-70899 histidine => urocanate + NH4+ IEA Sus scrofa 30817 R-SSC-70903 https://reactome.org/PathwayBrowser/#/R-SSC-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Sus scrofa 30817 R-XTR-70899 https://reactome.org/PathwayBrowser/#/R-XTR-70899 histidine => urocanate + NH4+ IEA Xenopus tropicalis 30817 R-XTR-70903 https://reactome.org/PathwayBrowser/#/R-XTR-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Xenopus tropicalis 3082 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 3082 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 3082 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 3082 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 3082 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 3082 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 3082 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 3082 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 3082 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 3082 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 3082 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 3082 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 3082 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 3082 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 3082 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 3082 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 3082 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 3082 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 3082 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 3082 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 3082 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 3082 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 3082 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 3082 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 3082 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 3082 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 3082 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 3082 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 3082 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 3082 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 3082 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 3082 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 3082 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 3082 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 3082 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 3082 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 3082 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 30823 R-BTA-9673053 https://reactome.org/PathwayBrowser/#/R-BTA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Bos taurus 30823 R-BTA-9673054 https://reactome.org/PathwayBrowser/#/R-BTA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Bos taurus 30823 R-CFA-9673053 https://reactome.org/PathwayBrowser/#/R-CFA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Canis familiaris 30823 R-CFA-9673054 https://reactome.org/PathwayBrowser/#/R-CFA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Canis familiaris 30823 R-DDI-9673053 https://reactome.org/PathwayBrowser/#/R-DDI-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Dictyostelium discoideum 30823 R-DDI-9673054 https://reactome.org/PathwayBrowser/#/R-DDI-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Dictyostelium discoideum 30823 R-DRE-9673053 https://reactome.org/PathwayBrowser/#/R-DRE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Danio rerio 30823 R-DRE-9673054 https://reactome.org/PathwayBrowser/#/R-DRE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Danio rerio 30823 R-GGA-9673053 https://reactome.org/PathwayBrowser/#/R-GGA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Gallus gallus 30823 R-GGA-9673054 https://reactome.org/PathwayBrowser/#/R-GGA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Gallus gallus 30823 R-HSA-9673053 https://reactome.org/PathwayBrowser/#/R-HSA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe TAS Homo sapiens 30823 R-HSA-9673054 https://reactome.org/PathwayBrowser/#/R-HSA-9673054 PM20D1 hydrolyzes oleoyl-phe TAS Homo sapiens 30823 R-MMU-9673053 https://reactome.org/PathwayBrowser/#/R-MMU-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Mus musculus 30823 R-MMU-9673054 https://reactome.org/PathwayBrowser/#/R-MMU-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Mus musculus 30823 R-RNO-9673053 https://reactome.org/PathwayBrowser/#/R-RNO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Rattus norvegicus 30823 R-RNO-9673054 https://reactome.org/PathwayBrowser/#/R-RNO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Rattus norvegicus 30823 R-SCE-9673053 https://reactome.org/PathwayBrowser/#/R-SCE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Saccharomyces cerevisiae 30823 R-SCE-9673054 https://reactome.org/PathwayBrowser/#/R-SCE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Saccharomyces cerevisiae 30823 R-SPO-9673053 https://reactome.org/PathwayBrowser/#/R-SPO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Schizosaccharomyces pombe 30823 R-SPO-9673054 https://reactome.org/PathwayBrowser/#/R-SPO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Schizosaccharomyces pombe 30823 R-SSC-9673053 https://reactome.org/PathwayBrowser/#/R-SSC-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Sus scrofa 30823 R-SSC-9673054 https://reactome.org/PathwayBrowser/#/R-SSC-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Sus scrofa 30823 R-XTR-9673053 https://reactome.org/PathwayBrowser/#/R-XTR-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Xenopus tropicalis 30823 R-XTR-9673054 https://reactome.org/PathwayBrowser/#/R-XTR-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Xenopus tropicalis 30831 R-BTA-1614583 https://reactome.org/PathwayBrowser/#/R-BTA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Bos taurus 30831 R-BTA-1614631 https://reactome.org/PathwayBrowser/#/R-BTA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Bos taurus 30831 R-BTA-9014641 https://reactome.org/PathwayBrowser/#/R-BTA-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Bos taurus 30831 R-CEL-1614583 https://reactome.org/PathwayBrowser/#/R-CEL-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Caenorhabditis elegans 30831 R-CEL-1614631 https://reactome.org/PathwayBrowser/#/R-CEL-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Caenorhabditis elegans 30831 R-CEL-9014641 https://reactome.org/PathwayBrowser/#/R-CEL-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Caenorhabditis elegans 30831 R-CFA-1614583 https://reactome.org/PathwayBrowser/#/R-CFA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Canis familiaris 30831 R-CFA-1614631 https://reactome.org/PathwayBrowser/#/R-CFA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Canis familiaris 30831 R-CFA-9014641 https://reactome.org/PathwayBrowser/#/R-CFA-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Canis familiaris 30831 R-DDI-1614583 https://reactome.org/PathwayBrowser/#/R-DDI-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Dictyostelium discoideum 30831 R-DDI-1614631 https://reactome.org/PathwayBrowser/#/R-DDI-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Dictyostelium discoideum 30831 R-DDI-9014641 https://reactome.org/PathwayBrowser/#/R-DDI-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Dictyostelium discoideum 30831 R-DME-1614583 https://reactome.org/PathwayBrowser/#/R-DME-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Drosophila melanogaster 30831 R-DME-1614631 https://reactome.org/PathwayBrowser/#/R-DME-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Drosophila melanogaster 30831 R-DME-9014641 https://reactome.org/PathwayBrowser/#/R-DME-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Drosophila melanogaster 30831 R-DRE-1614583 https://reactome.org/PathwayBrowser/#/R-DRE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Danio rerio 30831 R-DRE-1614631 https://reactome.org/PathwayBrowser/#/R-DRE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Danio rerio 30831 R-DRE-9014641 https://reactome.org/PathwayBrowser/#/R-DRE-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Danio rerio 30831 R-GGA-1614583 https://reactome.org/PathwayBrowser/#/R-GGA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Gallus gallus 30831 R-GGA-1614631 https://reactome.org/PathwayBrowser/#/R-GGA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Gallus gallus 30831 R-GGA-9014641 https://reactome.org/PathwayBrowser/#/R-GGA-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Gallus gallus 30831 R-HSA-1614583 https://reactome.org/PathwayBrowser/#/R-HSA-1614583 PXLP-K212-CTH cleaves L-Cystathionine TAS Homo sapiens 30831 R-HSA-1614631 https://reactome.org/PathwayBrowser/#/R-HSA-1614631 Homocysteine is degraded to oxobutanoate and H2S TAS Homo sapiens 30831 R-HSA-2408537 https://reactome.org/PathwayBrowser/#/R-HSA-2408537 Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH IEA Homo sapiens 30831 R-HSA-2408543 https://reactome.org/PathwayBrowser/#/R-HSA-2408543 SeCysta is hydrolysed to Sec by PXLP-K212-CTH IEA Homo sapiens 30831 R-HSA-9014641 https://reactome.org/PathwayBrowser/#/R-HSA-9014641 HRSP12 deaminates 2AA to 2OBUTA TAS Homo sapiens 30831 R-MMU-1614583 https://reactome.org/PathwayBrowser/#/R-MMU-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Mus musculus 30831 R-MMU-1614631 https://reactome.org/PathwayBrowser/#/R-MMU-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Mus musculus 30831 R-MMU-2408528 https://reactome.org/PathwayBrowser/#/R-MMU-2408528 Excess SeMet is cleaved into MeSeH by PXLP-K211-Cth TAS Mus musculus 30831 R-MMU-9014641 https://reactome.org/PathwayBrowser/#/R-MMU-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Mus musculus 30831 R-MTU-937192 https://reactome.org/PathwayBrowser/#/R-MTU-937192 Cysteine from cystathionine and vice versa TAS Mycobacterium tuberculosis 30831 R-RNO-1614583 https://reactome.org/PathwayBrowser/#/R-RNO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Rattus norvegicus 30831 R-RNO-1614631 https://reactome.org/PathwayBrowser/#/R-RNO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Rattus norvegicus 30831 R-RNO-2408502 https://reactome.org/PathwayBrowser/#/R-RNO-2408502 SeCysta is hydrolysed to Sec by PXLP-K211-Cth TAS Rattus norvegicus 30831 R-RNO-9014641 https://reactome.org/PathwayBrowser/#/R-RNO-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Rattus norvegicus 30831 R-SCE-1614583 https://reactome.org/PathwayBrowser/#/R-SCE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Saccharomyces cerevisiae 30831 R-SCE-1614631 https://reactome.org/PathwayBrowser/#/R-SCE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Saccharomyces cerevisiae 30831 R-SCE-9014641 https://reactome.org/PathwayBrowser/#/R-SCE-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Saccharomyces cerevisiae 30831 R-SPO-1614583 https://reactome.org/PathwayBrowser/#/R-SPO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Schizosaccharomyces pombe 30831 R-SPO-1614631 https://reactome.org/PathwayBrowser/#/R-SPO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Schizosaccharomyces pombe 30831 R-SPO-9014641 https://reactome.org/PathwayBrowser/#/R-SPO-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Schizosaccharomyces pombe 30831 R-SSC-1614583 https://reactome.org/PathwayBrowser/#/R-SSC-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Sus scrofa 30831 R-SSC-1614631 https://reactome.org/PathwayBrowser/#/R-SSC-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Sus scrofa 30831 R-SSC-9014641 https://reactome.org/PathwayBrowser/#/R-SSC-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Sus scrofa 30831 R-XTR-1614583 https://reactome.org/PathwayBrowser/#/R-XTR-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Xenopus tropicalis 30831 R-XTR-1614631 https://reactome.org/PathwayBrowser/#/R-XTR-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Xenopus tropicalis 30831 R-XTR-9014641 https://reactome.org/PathwayBrowser/#/R-XTR-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Xenopus tropicalis 30839 R-BTA-73567 https://reactome.org/PathwayBrowser/#/R-BTA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Bos taurus 30839 R-BTA-73569 https://reactome.org/PathwayBrowser/#/R-BTA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Bos taurus 30839 R-CEL-73567 https://reactome.org/PathwayBrowser/#/R-CEL-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Caenorhabditis elegans 30839 R-CEL-73569 https://reactome.org/PathwayBrowser/#/R-CEL-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Caenorhabditis elegans 30839 R-CFA-73567 https://reactome.org/PathwayBrowser/#/R-CFA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Canis familiaris 30839 R-CFA-73569 https://reactome.org/PathwayBrowser/#/R-CFA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Canis familiaris 30839 R-DDI-73567 https://reactome.org/PathwayBrowser/#/R-DDI-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Dictyostelium discoideum 30839 R-DME-73567 https://reactome.org/PathwayBrowser/#/R-DME-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Drosophila melanogaster 30839 R-DME-73569 https://reactome.org/PathwayBrowser/#/R-DME-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Drosophila melanogaster 30839 R-DRE-73569 https://reactome.org/PathwayBrowser/#/R-DRE-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Danio rerio 30839 R-GGA-419452 https://reactome.org/PathwayBrowser/#/R-GGA-419452 (S)-dihydroorotate + ubiquinone => orotate + ubiquinol IEA Gallus gallus 30839 R-GGA-419462 https://reactome.org/PathwayBrowser/#/R-GGA-419462 orotate + 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) <=> orotidine 5'-monophosphate (OMP) + pyrophosphate IEA Gallus gallus 30839 R-GGA-73567 https://reactome.org/PathwayBrowser/#/R-GGA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Gallus gallus 30839 R-GGA-73569 https://reactome.org/PathwayBrowser/#/R-GGA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Gallus gallus 30839 R-HSA-73567 https://reactome.org/PathwayBrowser/#/R-HSA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP TAS Homo sapiens 30839 R-HSA-73569 https://reactome.org/PathwayBrowser/#/R-HSA-73569 DHODH:FMN oxidises (S)-DHO to orotate TAS Homo sapiens 30839 R-MMU-73567 https://reactome.org/PathwayBrowser/#/R-MMU-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Mus musculus 30839 R-MMU-73569 https://reactome.org/PathwayBrowser/#/R-MMU-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Mus musculus 30839 R-PFA-73569 https://reactome.org/PathwayBrowser/#/R-PFA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Plasmodium falciparum 30839 R-RNO-73567 https://reactome.org/PathwayBrowser/#/R-RNO-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Rattus norvegicus 30839 R-RNO-73569 https://reactome.org/PathwayBrowser/#/R-RNO-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Rattus norvegicus 30839 R-SPO-73569 https://reactome.org/PathwayBrowser/#/R-SPO-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Schizosaccharomyces pombe 30839 R-SSC-73567 https://reactome.org/PathwayBrowser/#/R-SSC-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Sus scrofa 30839 R-SSC-73569 https://reactome.org/PathwayBrowser/#/R-SSC-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Sus scrofa 30839 R-XTR-73567 https://reactome.org/PathwayBrowser/#/R-XTR-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Xenopus tropicalis 30839 R-XTR-73569 https://reactome.org/PathwayBrowser/#/R-XTR-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Xenopus tropicalis 30864 R-BTA-73569 https://reactome.org/PathwayBrowser/#/R-BTA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Bos taurus 30864 R-BTA-73571 https://reactome.org/PathwayBrowser/#/R-BTA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Bos taurus 30864 R-CEL-73569 https://reactome.org/PathwayBrowser/#/R-CEL-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Caenorhabditis elegans 30864 R-CEL-73571 https://reactome.org/PathwayBrowser/#/R-CEL-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Caenorhabditis elegans 30864 R-CFA-73569 https://reactome.org/PathwayBrowser/#/R-CFA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Canis familiaris 30864 R-CFA-73571 https://reactome.org/PathwayBrowser/#/R-CFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Canis familiaris 30864 R-DDI-73571 https://reactome.org/PathwayBrowser/#/R-DDI-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Dictyostelium discoideum 30864 R-DME-73569 https://reactome.org/PathwayBrowser/#/R-DME-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Drosophila melanogaster 30864 R-DME-73571 https://reactome.org/PathwayBrowser/#/R-DME-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Drosophila melanogaster 30864 R-DRE-73569 https://reactome.org/PathwayBrowser/#/R-DRE-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Danio rerio 30864 R-GGA-419452 https://reactome.org/PathwayBrowser/#/R-GGA-419452 (S)-dihydroorotate + ubiquinone => orotate + ubiquinol IEA Gallus gallus 30864 R-GGA-419465 https://reactome.org/PathwayBrowser/#/R-GGA-419465 N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O IEA Gallus gallus 30864 R-GGA-73569 https://reactome.org/PathwayBrowser/#/R-GGA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Gallus gallus 30864 R-HSA-73569 https://reactome.org/PathwayBrowser/#/R-HSA-73569 DHODH:FMN oxidises (S)-DHO to orotate TAS Homo sapiens 30864 R-HSA-73571 https://reactome.org/PathwayBrowser/#/R-HSA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO TAS Homo sapiens 30864 R-MMU-73569 https://reactome.org/PathwayBrowser/#/R-MMU-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Mus musculus 30864 R-MMU-73571 https://reactome.org/PathwayBrowser/#/R-MMU-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Mus musculus 30864 R-PFA-73569 https://reactome.org/PathwayBrowser/#/R-PFA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Plasmodium falciparum 30864 R-PFA-73571 https://reactome.org/PathwayBrowser/#/R-PFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Plasmodium falciparum 30864 R-RNO-73569 https://reactome.org/PathwayBrowser/#/R-RNO-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Rattus norvegicus 30864 R-RNO-73571 https://reactome.org/PathwayBrowser/#/R-RNO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Rattus norvegicus 30864 R-SCE-73571 https://reactome.org/PathwayBrowser/#/R-SCE-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Saccharomyces cerevisiae 30864 R-SPO-73569 https://reactome.org/PathwayBrowser/#/R-SPO-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Schizosaccharomyces pombe 30864 R-SPO-73571 https://reactome.org/PathwayBrowser/#/R-SPO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Schizosaccharomyces pombe 30864 R-SSC-73569 https://reactome.org/PathwayBrowser/#/R-SSC-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Sus scrofa 30864 R-SSC-73571 https://reactome.org/PathwayBrowser/#/R-SSC-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Sus scrofa 30864 R-XTR-73569 https://reactome.org/PathwayBrowser/#/R-XTR-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Xenopus tropicalis 30864 R-XTR-73571 https://reactome.org/PathwayBrowser/#/R-XTR-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Xenopus tropicalis 30879 R-BTA-8878787 https://reactome.org/PathwayBrowser/#/R-BTA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Bos taurus 30879 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 30879 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 30879 R-CFA-8878787 https://reactome.org/PathwayBrowser/#/R-CFA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Canis familiaris 30879 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 30879 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 30879 R-DME-8878787 https://reactome.org/PathwayBrowser/#/R-DME-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Drosophila melanogaster 30879 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 30879 R-DRE-8878787 https://reactome.org/PathwayBrowser/#/R-DRE-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Danio rerio 30879 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 30879 R-GGA-8878787 https://reactome.org/PathwayBrowser/#/R-GGA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Gallus gallus 30879 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 30879 R-HSA-8878787 https://reactome.org/PathwayBrowser/#/R-HSA-8878787 ALPI dimer hydrolyses phosphate monoesters TAS Homo sapiens 30879 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 30879 R-MMU-8878787 https://reactome.org/PathwayBrowser/#/R-MMU-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Mus musculus 30879 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 30879 R-RNO-8878787 https://reactome.org/PathwayBrowser/#/R-RNO-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Rattus norvegicus 30879 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 30879 R-SSC-8878787 https://reactome.org/PathwayBrowser/#/R-SSC-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Sus scrofa 30879 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 30879 R-XTR-8878787 https://reactome.org/PathwayBrowser/#/R-XTR-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Xenopus tropicalis 30879 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 30882 R-BTA-893616 https://reactome.org/PathwayBrowser/#/R-BTA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Bos taurus 30882 R-CEL-893616 https://reactome.org/PathwayBrowser/#/R-CEL-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Caenorhabditis elegans 30882 R-CFA-893616 https://reactome.org/PathwayBrowser/#/R-CFA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Canis familiaris 30882 R-DDI-893616 https://reactome.org/PathwayBrowser/#/R-DDI-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Dictyostelium discoideum 30882 R-DME-893616 https://reactome.org/PathwayBrowser/#/R-DME-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Drosophila melanogaster 30882 R-DRE-893616 https://reactome.org/PathwayBrowser/#/R-DRE-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Danio rerio 30882 R-GGA-893616 https://reactome.org/PathwayBrowser/#/R-GGA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Gallus gallus 30882 R-HSA-893616 https://reactome.org/PathwayBrowser/#/R-HSA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine TAS Homo sapiens 30882 R-MMU-893616 https://reactome.org/PathwayBrowser/#/R-MMU-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Mus musculus 30882 R-RNO-893616 https://reactome.org/PathwayBrowser/#/R-RNO-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Rattus norvegicus 30882 R-SCE-893616 https://reactome.org/PathwayBrowser/#/R-SCE-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Saccharomyces cerevisiae 30882 R-SPO-893616 https://reactome.org/PathwayBrowser/#/R-SPO-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Schizosaccharomyces pombe 30882 R-SSC-893616 https://reactome.org/PathwayBrowser/#/R-SSC-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Sus scrofa 30882 R-XTR-893616 https://reactome.org/PathwayBrowser/#/R-XTR-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Xenopus tropicalis 30933 R-BTA-977333 https://reactome.org/PathwayBrowser/#/R-BTA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Bos taurus 30933 R-BTA-977348 https://reactome.org/PathwayBrowser/#/R-BTA-977348 PHGDH tetramer dehydrogenates 3PG IEA Bos taurus 30933 R-CEL-977333 https://reactome.org/PathwayBrowser/#/R-CEL-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Caenorhabditis elegans 30933 R-CEL-977348 https://reactome.org/PathwayBrowser/#/R-CEL-977348 PHGDH tetramer dehydrogenates 3PG IEA Caenorhabditis elegans 30933 R-CFA-977333 https://reactome.org/PathwayBrowser/#/R-CFA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Canis familiaris 30933 R-CFA-977348 https://reactome.org/PathwayBrowser/#/R-CFA-977348 PHGDH tetramer dehydrogenates 3PG IEA Canis familiaris 30933 R-DDI-977333 https://reactome.org/PathwayBrowser/#/R-DDI-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Dictyostelium discoideum 30933 R-DME-977333 https://reactome.org/PathwayBrowser/#/R-DME-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Drosophila melanogaster 30933 R-DME-977348 https://reactome.org/PathwayBrowser/#/R-DME-977348 PHGDH tetramer dehydrogenates 3PG IEA Drosophila melanogaster 30933 R-DRE-977333 https://reactome.org/PathwayBrowser/#/R-DRE-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Danio rerio 30933 R-GGA-977333 https://reactome.org/PathwayBrowser/#/R-GGA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Gallus gallus 30933 R-HSA-977333 https://reactome.org/PathwayBrowser/#/R-HSA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA TAS Homo sapiens 30933 R-HSA-977348 https://reactome.org/PathwayBrowser/#/R-HSA-977348 PHGDH tetramer dehydrogenates 3PG TAS Homo sapiens 30933 R-MMU-977333 https://reactome.org/PathwayBrowser/#/R-MMU-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Mus musculus 30933 R-MMU-977348 https://reactome.org/PathwayBrowser/#/R-MMU-977348 PHGDH tetramer dehydrogenates 3PG IEA Mus musculus 30933 R-RNO-977333 https://reactome.org/PathwayBrowser/#/R-RNO-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Rattus norvegicus 30933 R-RNO-977348 https://reactome.org/PathwayBrowser/#/R-RNO-977348 PHGDH tetramer dehydrogenates 3PG IEA Rattus norvegicus 30933 R-SCE-977333 https://reactome.org/PathwayBrowser/#/R-SCE-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Saccharomyces cerevisiae 30933 R-SPO-977333 https://reactome.org/PathwayBrowser/#/R-SPO-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Schizosaccharomyces pombe 30933 R-SSC-977333 https://reactome.org/PathwayBrowser/#/R-SSC-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Sus scrofa 30933 R-SSC-977348 https://reactome.org/PathwayBrowser/#/R-SSC-977348 PHGDH tetramer dehydrogenates 3PG IEA Sus scrofa 30933 R-XTR-977333 https://reactome.org/PathwayBrowser/#/R-XTR-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Xenopus tropicalis 30933 R-XTR-977348 https://reactome.org/PathwayBrowser/#/R-XTR-977348 PHGDH tetramer dehydrogenates 3PG IEA Xenopus tropicalis 31011 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 31011 R-BTA-444047 https://reactome.org/PathwayBrowser/#/R-BTA-444047 Receptor FFAR3 binds carboxylates IEA Bos taurus 31011 R-BTA-444171 https://reactome.org/PathwayBrowser/#/R-BTA-444171 Receptor FFAR2 binds carboxylates IEA Bos taurus 31011 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 31011 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 31011 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 31011 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 31011 R-CFA-444047 https://reactome.org/PathwayBrowser/#/R-CFA-444047 Receptor FFAR3 binds carboxylates IEA Canis familiaris 31011 R-CFA-444171 https://reactome.org/PathwayBrowser/#/R-CFA-444171 Receptor FFAR2 binds carboxylates IEA Canis familiaris 31011 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 31011 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 31011 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 31011 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 31011 R-DRE-444047 https://reactome.org/PathwayBrowser/#/R-DRE-444047 Receptor FFAR3 binds carboxylates IEA Danio rerio 31011 R-DRE-444171 https://reactome.org/PathwayBrowser/#/R-DRE-444171 Receptor FFAR2 binds carboxylates IEA Danio rerio 31011 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 31011 R-GGA-444171 https://reactome.org/PathwayBrowser/#/R-GGA-444171 Receptor FFAR2 binds carboxylates IEA Gallus gallus 31011 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 31011 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 31011 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 31011 R-HSA-444047 https://reactome.org/PathwayBrowser/#/R-HSA-444047 Receptor FFAR3 binds carboxylates TAS Homo sapiens 31011 R-HSA-444171 https://reactome.org/PathwayBrowser/#/R-HSA-444171 Receptor FFAR2 binds carboxylates TAS Homo sapiens 31011 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 31011 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 31011 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 31011 R-MMU-444047 https://reactome.org/PathwayBrowser/#/R-MMU-444047 Receptor FFAR3 binds carboxylates IEA Mus musculus 31011 R-MMU-444171 https://reactome.org/PathwayBrowser/#/R-MMU-444171 Receptor FFAR2 binds carboxylates IEA Mus musculus 31011 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 31011 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 31011 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 31011 R-RNO-444047 https://reactome.org/PathwayBrowser/#/R-RNO-444047 Receptor FFAR3 binds carboxylates IEA Rattus norvegicus 31011 R-RNO-444171 https://reactome.org/PathwayBrowser/#/R-RNO-444171 Receptor FFAR2 binds carboxylates IEA Rattus norvegicus 31011 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 31011 R-SSC-444047 https://reactome.org/PathwayBrowser/#/R-SSC-444047 Receptor FFAR3 binds carboxylates IEA Sus scrofa 31011 R-SSC-444171 https://reactome.org/PathwayBrowser/#/R-SSC-444171 Receptor FFAR2 binds carboxylates IEA Sus scrofa 31011 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 31011 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 31011 R-XTR-444171 https://reactome.org/PathwayBrowser/#/R-XTR-444171 Receptor FFAR2 binds carboxylates IEA Xenopus tropicalis 31011 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 31011 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 310388 R-HSA-9793564 https://reactome.org/PathwayBrowser/#/R-HSA-9793564 Cipro HCl dissolves TAS Homo sapiens 31296 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 31296 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 31296 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 31296 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 31296 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 31296 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 31296 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 31296 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 31296 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 31296 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 31399 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 31399 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 31399 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 31399 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 31399 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 31399 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 31399 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 31399 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 31399 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 31399 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 31414 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 31414 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 31414 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 31414 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 31414 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 31414 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 31414 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 31414 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 31414 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 31414 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 31414 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 31414 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 31414 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 31414 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 31414 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 31414 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 31414 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 31414 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 31414 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 31414 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 31414 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 31414 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 31590 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 31590 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 31590 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 31590 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 31590 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 31590 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 31590 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 31590 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 31590 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 31590 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 31590 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 31654 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 31654 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 31654 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 31654 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 31654 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 31654 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 31654 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 31654 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 31654 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 31697 R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 31697 R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 31697 R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 31697 R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 31697 R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 31697 R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 31697 R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 31697 R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 31697 R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 31697 R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 31697 R-SSC-211968 https://reactome.org/PathwayBrowser/#/R-SSC-211968 CYP2W1 oxidises INDOL IEA Sus scrofa 31697 R-XTR-211968 https://reactome.org/PathwayBrowser/#/R-XTR-211968 CYP2W1 oxidises INDOL IEA Xenopus tropicalis 3175 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 3175 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 3175 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 3175 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 3175 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 3175 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 3175 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 3175 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 3175 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 3175 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 3175 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 31801 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 31801 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 31801 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 31801 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 31801 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 31801 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 31801 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 31801 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 31801 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 31801 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 31801 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 31882 R-BTA-5676966 https://reactome.org/PathwayBrowser/#/R-BTA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Bos taurus 31882 R-CEL-5676966 https://reactome.org/PathwayBrowser/#/R-CEL-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Caenorhabditis elegans 31882 R-CFA-5676966 https://reactome.org/PathwayBrowser/#/R-CFA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Canis familiaris 31882 R-DDI-5676966 https://reactome.org/PathwayBrowser/#/R-DDI-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Dictyostelium discoideum 31882 R-DME-5676966 https://reactome.org/PathwayBrowser/#/R-DME-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Drosophila melanogaster 31882 R-DRE-5676966 https://reactome.org/PathwayBrowser/#/R-DRE-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Danio rerio 31882 R-GGA-5676966 https://reactome.org/PathwayBrowser/#/R-GGA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Gallus gallus 31882 R-HSA-5676966 https://reactome.org/PathwayBrowser/#/R-HSA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp TAS Homo sapiens 31882 R-HSA-5687520 https://reactome.org/PathwayBrowser/#/R-HSA-5687520 MetAsp transforms to L-Asp,isoAsp TAS Homo sapiens 31882 R-MMU-5676966 https://reactome.org/PathwayBrowser/#/R-MMU-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Mus musculus 31882 R-PFA-5676966 https://reactome.org/PathwayBrowser/#/R-PFA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Plasmodium falciparum 31882 R-RNO-5676966 https://reactome.org/PathwayBrowser/#/R-RNO-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Rattus norvegicus 31882 R-SPO-5676966 https://reactome.org/PathwayBrowser/#/R-SPO-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Schizosaccharomyces pombe 31882 R-SSC-5676966 https://reactome.org/PathwayBrowser/#/R-SSC-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Sus scrofa 31897 R-BTA-9650858 https://reactome.org/PathwayBrowser/#/R-BTA-9650858 Meglitinides bind ABCC8 IEA Bos taurus 31897 R-CFA-9650858 https://reactome.org/PathwayBrowser/#/R-CFA-9650858 Meglitinides bind ABCC8 IEA Canis familiaris 31897 R-DME-9650858 https://reactome.org/PathwayBrowser/#/R-DME-9650858 Meglitinides bind ABCC8 IEA Drosophila melanogaster 31897 R-GGA-9650858 https://reactome.org/PathwayBrowser/#/R-GGA-9650858 Meglitinides bind ABCC8 IEA Gallus gallus 31897 R-HSA-9650858 https://reactome.org/PathwayBrowser/#/R-HSA-9650858 Meglitinides bind ABCC8 TAS Homo sapiens 31897 R-MMU-9650858 https://reactome.org/PathwayBrowser/#/R-MMU-9650858 Meglitinides bind ABCC8 IEA Mus musculus 31897 R-RNO-9650858 https://reactome.org/PathwayBrowser/#/R-RNO-9650858 Meglitinides bind ABCC8 IEA Rattus norvegicus 31897 R-SSC-9650858 https://reactome.org/PathwayBrowser/#/R-SSC-9650858 Meglitinides bind ABCC8 IEA Sus scrofa 31897 R-XTR-9650858 https://reactome.org/PathwayBrowser/#/R-XTR-9650858 Meglitinides bind ABCC8 IEA Xenopus tropicalis 3193 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 3193 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 3193 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 3193 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 3193 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 3193 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 3193 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 3193 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 3193 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 3193 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 3193 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 3193 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 3193 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 3193 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 3193 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 3193 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 3193 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 3193 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 3193 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 3193 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 3193 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 3193 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 3193 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 3193 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 3193 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 3193 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 3193 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 3193 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 3193 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 3193 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 3193 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 3193 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 3193 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 3193 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 3193 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 3193 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 3193 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 3193 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 3193 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 3193 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 3193 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 3193 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 31932 R-BTA-6786190 https://reactome.org/PathwayBrowser/#/R-BTA-6786190 CMBL hydrolyses OM to OLMS IEA Bos taurus 31932 R-CFA-6786190 https://reactome.org/PathwayBrowser/#/R-CFA-6786190 CMBL hydrolyses OM to OLMS IEA Canis familiaris 31932 R-DRE-6786190 https://reactome.org/PathwayBrowser/#/R-DRE-6786190 CMBL hydrolyses OM to OLMS IEA Danio rerio 31932 R-GGA-6786190 https://reactome.org/PathwayBrowser/#/R-GGA-6786190 CMBL hydrolyses OM to OLMS IEA Gallus gallus 31932 R-HSA-6786190 https://reactome.org/PathwayBrowser/#/R-HSA-6786190 CMBL hydrolyses OM to OLMS TAS Homo sapiens 31932 R-MMU-6786190 https://reactome.org/PathwayBrowser/#/R-MMU-6786190 CMBL hydrolyses OM to OLMS IEA Mus musculus 31932 R-RNO-6786190 https://reactome.org/PathwayBrowser/#/R-RNO-6786190 CMBL hydrolyses OM to OLMS IEA Rattus norvegicus 31932 R-SSC-6786190 https://reactome.org/PathwayBrowser/#/R-SSC-6786190 CMBL hydrolyses OM to OLMS IEA Sus scrofa 31932 R-XTR-6786190 https://reactome.org/PathwayBrowser/#/R-XTR-6786190 CMBL hydrolyses OM to OLMS IEA Xenopus tropicalis 31941 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 31941 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 31941 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 31941 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 31941 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 31941 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 31941 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 31941 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 31941 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 31941 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 31941 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 31941 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 31941 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 31941 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 31941 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 31941 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 31941 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 31941 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 31941 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 31941 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 31941 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 31941 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 31998 R-BTA-428262 https://reactome.org/PathwayBrowser/#/R-BTA-428262 ACER3 hydrolyzes phytoceramide IEA Bos taurus 31998 R-CFA-428262 https://reactome.org/PathwayBrowser/#/R-CFA-428262 ACER3 hydrolyzes phytoceramide IEA Canis familiaris 31998 R-DDI-428262 https://reactome.org/PathwayBrowser/#/R-DDI-428262 ACER3 hydrolyzes phytoceramide IEA Dictyostelium discoideum 31998 R-GGA-428262 https://reactome.org/PathwayBrowser/#/R-GGA-428262 ACER3 hydrolyzes phytoceramide IEA Gallus gallus 31998 R-HSA-428262 https://reactome.org/PathwayBrowser/#/R-HSA-428262 ACER3 hydrolyzes phytoceramide TAS Homo sapiens 31998 R-MMU-428262 https://reactome.org/PathwayBrowser/#/R-MMU-428262 ACER3 hydrolyzes phytoceramide IEA Mus musculus 31998 R-RNO-428262 https://reactome.org/PathwayBrowser/#/R-RNO-428262 ACER3 hydrolyzes phytoceramide IEA Rattus norvegicus 31998 R-SCE-428262 https://reactome.org/PathwayBrowser/#/R-SCE-428262 ACER3 hydrolyzes phytoceramide IEA Saccharomyces cerevisiae 31998 R-SSC-428262 https://reactome.org/PathwayBrowser/#/R-SSC-428262 ACER3 hydrolyzes phytoceramide IEA Sus scrofa 31998 R-XTR-428262 https://reactome.org/PathwayBrowser/#/R-XTR-428262 ACER3 hydrolyzes phytoceramide IEA Xenopus tropicalis 32111 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 32111 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 32111 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 32111 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 32111 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 32111 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 32111 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 32111 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 32111 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 32111 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 32111 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 32111 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 32111 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 32111 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 32111 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 32111 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 32111 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 32111 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 32111 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 32111 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 32111 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 32111 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 32111 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 32111 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 32111 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 32111 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 32111 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 32111 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 32111 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 32111 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 32111 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 32111 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 32111 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 32111 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 32111 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 32111 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 32111 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 32111 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 32111 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 32168 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 32168 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 32168 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 32168 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 32168 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 32168 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 32168 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 32168 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 32168 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 32168 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 32193 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 32193 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 32193 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 32193 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 32193 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 32193 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 32193 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 32193 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 32193 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 32193 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 32193 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 32193 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 32193 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 32193 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 32193 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 32193 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 32193 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 32193 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 32193 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 32193 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 32325 R-BTA-5164399 https://reactome.org/PathwayBrowser/#/R-BTA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Bos taurus 32325 R-CEL-5164399 https://reactome.org/PathwayBrowser/#/R-CEL-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Caenorhabditis elegans 32325 R-CFA-5164399 https://reactome.org/PathwayBrowser/#/R-CFA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Canis familiaris 32325 R-DME-5164399 https://reactome.org/PathwayBrowser/#/R-DME-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Drosophila melanogaster 32325 R-DRE-5164399 https://reactome.org/PathwayBrowser/#/R-DRE-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Danio rerio 32325 R-GGA-5164399 https://reactome.org/PathwayBrowser/#/R-GGA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Gallus gallus 32325 R-HSA-5164399 https://reactome.org/PathwayBrowser/#/R-HSA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION TAS Homo sapiens 32325 R-MMU-5164399 https://reactome.org/PathwayBrowser/#/R-MMU-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Mus musculus 32325 R-RNO-5164399 https://reactome.org/PathwayBrowser/#/R-RNO-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Rattus norvegicus 32325 R-SSC-5164399 https://reactome.org/PathwayBrowser/#/R-SSC-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Sus scrofa 32325 R-XTR-5164399 https://reactome.org/PathwayBrowser/#/R-XTR-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Xenopus tropicalis 32364 R-MTU-964851 https://reactome.org/PathwayBrowser/#/R-MTU-964851 Dehydratation of DHQ yields DHS TAS Mycobacterium tuberculosis 32364 R-MTU-964914 https://reactome.org/PathwayBrowser/#/R-MTU-964914 DHQ from DAHP dephosphorylation TAS Mycobacterium tuberculosis 32386 R-BTA-2404137 https://reactome.org/PathwayBrowser/#/R-BTA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 32386 R-BTA-2453855 https://reactome.org/PathwayBrowser/#/R-BTA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 32386 R-BTA-975608 https://reactome.org/PathwayBrowser/#/R-BTA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Bos taurus 32386 R-CFA-2404137 https://reactome.org/PathwayBrowser/#/R-CFA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 32386 R-CFA-2453855 https://reactome.org/PathwayBrowser/#/R-CFA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 32386 R-CFA-975608 https://reactome.org/PathwayBrowser/#/R-CFA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Canis familiaris 32386 R-DRE-2404137 https://reactome.org/PathwayBrowser/#/R-DRE-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 32386 R-DRE-2453855 https://reactome.org/PathwayBrowser/#/R-DRE-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 32386 R-DRE-975608 https://reactome.org/PathwayBrowser/#/R-DRE-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Danio rerio 32386 R-GGA-2404137 https://reactome.org/PathwayBrowser/#/R-GGA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 32386 R-GGA-2453855 https://reactome.org/PathwayBrowser/#/R-GGA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 32386 R-GGA-975608 https://reactome.org/PathwayBrowser/#/R-GGA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Gallus gallus 32386 R-HSA-2404137 https://reactome.org/PathwayBrowser/#/R-HSA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 32386 R-HSA-2453855 https://reactome.org/PathwayBrowser/#/R-HSA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 32386 R-HSA-2466710 https://reactome.org/PathwayBrowser/#/R-HSA-2466710 Defective LRAT does not esterify RBP1:atROL and FACYLs to atREs TAS Homo sapiens 32386 R-HSA-975608 https://reactome.org/PathwayBrowser/#/R-HSA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs TAS Homo sapiens 32386 R-MMU-2404137 https://reactome.org/PathwayBrowser/#/R-MMU-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 32386 R-MMU-2453855 https://reactome.org/PathwayBrowser/#/R-MMU-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 32386 R-MMU-975608 https://reactome.org/PathwayBrowser/#/R-MMU-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Mus musculus 32386 R-RNO-2404137 https://reactome.org/PathwayBrowser/#/R-RNO-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 32386 R-RNO-2453855 https://reactome.org/PathwayBrowser/#/R-RNO-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 32386 R-RNO-975608 https://reactome.org/PathwayBrowser/#/R-RNO-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Rattus norvegicus 32386 R-SSC-2404137 https://reactome.org/PathwayBrowser/#/R-SSC-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 32386 R-SSC-2453855 https://reactome.org/PathwayBrowser/#/R-SSC-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 32386 R-SSC-975608 https://reactome.org/PathwayBrowser/#/R-SSC-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Sus scrofa 32386 R-XTR-2404137 https://reactome.org/PathwayBrowser/#/R-XTR-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 32386 R-XTR-2453855 https://reactome.org/PathwayBrowser/#/R-XTR-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 32386 R-XTR-975608 https://reactome.org/PathwayBrowser/#/R-XTR-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Xenopus tropicalis 32395 R-BTA-111883 https://reactome.org/PathwayBrowser/#/R-BTA-111883 Hydrolysis of phosphatidylcholine IEA Bos taurus 32395 R-BTA-140355 https://reactome.org/PathwayBrowser/#/R-BTA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Bos taurus 32395 R-BTA-2029475 https://reactome.org/PathwayBrowser/#/R-BTA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Bos taurus 32395 R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 32395 R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 32395 R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 32395 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 32395 R-BTA-2161794 https://reactome.org/PathwayBrowser/#/R-BTA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Bos taurus 32395 R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Bos taurus 32395 R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 32395 R-BTA-2161890 https://reactome.org/PathwayBrowser/#/R-BTA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Bos taurus 32395 R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Bos taurus 32395 R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 32395 R-BTA-2161948 https://reactome.org/PathwayBrowser/#/R-BTA-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Bos taurus 32395 R-BTA-2161950 https://reactome.org/PathwayBrowser/#/R-BTA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Bos taurus 32395 R-BTA-2161951 https://reactome.org/PathwayBrowser/#/R-BTA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Bos taurus 32395 R-BTA-2161964 https://reactome.org/PathwayBrowser/#/R-BTA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Bos taurus 32395 R-BTA-2162002 https://reactome.org/PathwayBrowser/#/R-BTA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Bos taurus 32395 R-BTA-2309787 https://reactome.org/PathwayBrowser/#/R-BTA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Bos taurus 32395 R-BTA-265296 https://reactome.org/PathwayBrowser/#/R-BTA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Bos taurus 32395 R-BTA-400143 https://reactome.org/PathwayBrowser/#/R-BTA-400143 Fatty acid ligands activate PPARA IEA Bos taurus 32395 R-BTA-426043 https://reactome.org/PathwayBrowser/#/R-BTA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Bos taurus 32395 R-BTA-548843 https://reactome.org/PathwayBrowser/#/R-BTA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Bos taurus 32395 R-BTA-5668629 https://reactome.org/PathwayBrowser/#/R-BTA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Bos taurus 32395 R-BTA-5693742 https://reactome.org/PathwayBrowser/#/R-BTA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Bos taurus 32395 R-BTA-5694462 https://reactome.org/PathwayBrowser/#/R-BTA-5694462 ABHD6,12 hydrolyse 3AG IEA Bos taurus 32395 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 32395 R-BTA-9626848 https://reactome.org/PathwayBrowser/#/R-BTA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Bos taurus 32395 R-CEL-2029475 https://reactome.org/PathwayBrowser/#/R-CEL-2029475 Production of AA by iPLA2 upon FCGR activation IEA Caenorhabditis elegans 32395 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 32395 R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 32395 R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans 32395 R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Caenorhabditis elegans 32395 R-CEL-548843 https://reactome.org/PathwayBrowser/#/R-CEL-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Caenorhabditis elegans 32395 R-CEL-5693742 https://reactome.org/PathwayBrowser/#/R-CEL-5693742 FAAH hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 32395 R-CEL-5693751 https://reactome.org/PathwayBrowser/#/R-CEL-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 32395 R-CEL-5694462 https://reactome.org/PathwayBrowser/#/R-CEL-5694462 ABHD6,12 hydrolyse 3AG IEA Caenorhabditis elegans 32395 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 32395 R-CFA-111883 https://reactome.org/PathwayBrowser/#/R-CFA-111883 Hydrolysis of phosphatidylcholine IEA Canis familiaris 32395 R-CFA-140355 https://reactome.org/PathwayBrowser/#/R-CFA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Canis familiaris 32395 R-CFA-2029475 https://reactome.org/PathwayBrowser/#/R-CFA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Canis familiaris 32395 R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 32395 R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 32395 R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 32395 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 32395 R-CFA-2161794 https://reactome.org/PathwayBrowser/#/R-CFA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Canis familiaris 32395 R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Canis familiaris 32395 R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 32395 R-CFA-2161890 https://reactome.org/PathwayBrowser/#/R-CFA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Canis familiaris 32395 R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Canis familiaris 32395 R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 32395 R-CFA-2161948 https://reactome.org/PathwayBrowser/#/R-CFA-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Canis familiaris 32395 R-CFA-2161950 https://reactome.org/PathwayBrowser/#/R-CFA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Canis familiaris 32395 R-CFA-2161951 https://reactome.org/PathwayBrowser/#/R-CFA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Canis familiaris 32395 R-CFA-2161964 https://reactome.org/PathwayBrowser/#/R-CFA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Canis familiaris 32395 R-CFA-2162002 https://reactome.org/PathwayBrowser/#/R-CFA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Canis familiaris 32395 R-CFA-2309787 https://reactome.org/PathwayBrowser/#/R-CFA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Canis familiaris 32395 R-CFA-265296 https://reactome.org/PathwayBrowser/#/R-CFA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Canis familiaris 32395 R-CFA-400143 https://reactome.org/PathwayBrowser/#/R-CFA-400143 Fatty acid ligands activate PPARA IEA Canis familiaris 32395 R-CFA-426043 https://reactome.org/PathwayBrowser/#/R-CFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Canis familiaris 32395 R-CFA-548843 https://reactome.org/PathwayBrowser/#/R-CFA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Canis familiaris 32395 R-CFA-5668629 https://reactome.org/PathwayBrowser/#/R-CFA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Canis familiaris 32395 R-CFA-5693742 https://reactome.org/PathwayBrowser/#/R-CFA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Canis familiaris 32395 R-CFA-5694462 https://reactome.org/PathwayBrowser/#/R-CFA-5694462 ABHD6,12 hydrolyse 3AG IEA Canis familiaris 32395 R-CFA-9626848 https://reactome.org/PathwayBrowser/#/R-CFA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Canis familiaris 32395 R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 32395 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 32395 R-DDI-2161794 https://reactome.org/PathwayBrowser/#/R-DDI-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Dictyostelium discoideum 32395 R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 32395 R-DDI-2161890 https://reactome.org/PathwayBrowser/#/R-DDI-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Dictyostelium discoideum 32395 R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Dictyostelium discoideum 32395 R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 32395 R-DDI-2161948 https://reactome.org/PathwayBrowser/#/R-DDI-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Dictyostelium discoideum 32395 R-DDI-2161950 https://reactome.org/PathwayBrowser/#/R-DDI-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Dictyostelium discoideum 32395 R-DDI-2161964 https://reactome.org/PathwayBrowser/#/R-DDI-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Dictyostelium discoideum 32395 R-DDI-2162002 https://reactome.org/PathwayBrowser/#/R-DDI-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Dictyostelium discoideum 32395 R-DDI-265296 https://reactome.org/PathwayBrowser/#/R-DDI-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Dictyostelium discoideum 32395 R-DDI-426043 https://reactome.org/PathwayBrowser/#/R-DDI-426043 2-AG hydrolysis to arachidonate by MAGL IEA Dictyostelium discoideum 32395 R-DME-2029475 https://reactome.org/PathwayBrowser/#/R-DME-2029475 Production of AA by iPLA2 upon FCGR activation IEA Drosophila melanogaster 32395 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 32395 R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 32395 R-DME-2161890 https://reactome.org/PathwayBrowser/#/R-DME-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Drosophila melanogaster 32395 R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Drosophila melanogaster 32395 R-DME-400143 https://reactome.org/PathwayBrowser/#/R-DME-400143 Fatty acid ligands activate PPARA IEA Drosophila melanogaster 32395 R-DME-548843 https://reactome.org/PathwayBrowser/#/R-DME-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Drosophila melanogaster 32395 R-DME-5693751 https://reactome.org/PathwayBrowser/#/R-DME-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Drosophila melanogaster 32395 R-DME-5694462 https://reactome.org/PathwayBrowser/#/R-DME-5694462 ABHD6,12 hydrolyse 3AG IEA Drosophila melanogaster 32395 R-DRE-111883 https://reactome.org/PathwayBrowser/#/R-DRE-111883 Hydrolysis of phosphatidylcholine IEA Danio rerio 32395 R-DRE-140355 https://reactome.org/PathwayBrowser/#/R-DRE-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Danio rerio 32395 R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 32395 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 32395 R-DRE-2161794 https://reactome.org/PathwayBrowser/#/R-DRE-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Danio rerio 32395 R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Danio rerio 32395 R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 32395 R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio 32395 R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Danio rerio 32395 R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 32395 R-DRE-2161948 https://reactome.org/PathwayBrowser/#/R-DRE-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Danio rerio 32395 R-DRE-2161950 https://reactome.org/PathwayBrowser/#/R-DRE-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Danio rerio 32395 R-DRE-2161951 https://reactome.org/PathwayBrowser/#/R-DRE-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Danio rerio 32395 R-DRE-2161964 https://reactome.org/PathwayBrowser/#/R-DRE-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Danio rerio 32395 R-DRE-2162002 https://reactome.org/PathwayBrowser/#/R-DRE-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Danio rerio 32395 R-DRE-2309787 https://reactome.org/PathwayBrowser/#/R-DRE-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Danio rerio 32395 R-DRE-400143 https://reactome.org/PathwayBrowser/#/R-DRE-400143 Fatty acid ligands activate PPARA IEA Danio rerio 32395 R-DRE-426043 https://reactome.org/PathwayBrowser/#/R-DRE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Danio rerio 32395 R-DRE-548843 https://reactome.org/PathwayBrowser/#/R-DRE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Danio rerio 32395 R-DRE-5668629 https://reactome.org/PathwayBrowser/#/R-DRE-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Danio rerio 32395 R-DRE-5693751 https://reactome.org/PathwayBrowser/#/R-DRE-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Danio rerio 32395 R-DRE-5694462 https://reactome.org/PathwayBrowser/#/R-DRE-5694462 ABHD6,12 hydrolyse 3AG IEA Danio rerio 32395 R-DRE-9626848 https://reactome.org/PathwayBrowser/#/R-DRE-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Danio rerio 32395 R-GGA-111883 https://reactome.org/PathwayBrowser/#/R-GGA-111883 Hydrolysis of phosphatidylcholine IEA Gallus gallus 32395 R-GGA-140355 https://reactome.org/PathwayBrowser/#/R-GGA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Gallus gallus 32395 R-GGA-2029475 https://reactome.org/PathwayBrowser/#/R-GGA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Gallus gallus 32395 R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 32395 R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 32395 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 32395 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Gallus gallus 32395 R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 32395 R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus 32395 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Gallus gallus 32395 R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 32395 R-GGA-2161950 https://reactome.org/PathwayBrowser/#/R-GGA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Gallus gallus 32395 R-GGA-2161951 https://reactome.org/PathwayBrowser/#/R-GGA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Gallus gallus 32395 R-GGA-2162002 https://reactome.org/PathwayBrowser/#/R-GGA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Gallus gallus 32395 R-GGA-2309787 https://reactome.org/PathwayBrowser/#/R-GGA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Gallus gallus 32395 R-GGA-265296 https://reactome.org/PathwayBrowser/#/R-GGA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Gallus gallus 32395 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus 32395 R-GGA-426043 https://reactome.org/PathwayBrowser/#/R-GGA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Gallus gallus 32395 R-GGA-548843 https://reactome.org/PathwayBrowser/#/R-GGA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Gallus gallus 32395 R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus 32395 R-GGA-5693742 https://reactome.org/PathwayBrowser/#/R-GGA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Gallus gallus 32395 R-GGA-5693751 https://reactome.org/PathwayBrowser/#/R-GGA-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Gallus gallus 32395 R-GGA-5694462 https://reactome.org/PathwayBrowser/#/R-GGA-5694462 ABHD6,12 hydrolyse 3AG IEA Gallus gallus 32395 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 32395 R-GGA-9626848 https://reactome.org/PathwayBrowser/#/R-GGA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Gallus gallus 32395 R-HSA-111883 https://reactome.org/PathwayBrowser/#/R-HSA-111883 Hydrolysis of phosphatidylcholine TAS Homo sapiens 32395 R-HSA-1368065 https://reactome.org/PathwayBrowser/#/R-HSA-1368065 Expression of NPAS2 IEA Homo sapiens 32395 R-HSA-140355 https://reactome.org/PathwayBrowser/#/R-HSA-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 TAS Homo sapiens 32395 R-HSA-1592238 https://reactome.org/PathwayBrowser/#/R-HSA-1592238 Expression of ALAS1 TAS Homo sapiens 32395 R-HSA-1655826 https://reactome.org/PathwayBrowser/#/R-HSA-1655826 Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) TAS Homo sapiens 32395 R-HSA-1655848 https://reactome.org/PathwayBrowser/#/R-HSA-1655848 Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) TAS Homo sapiens 32395 R-HSA-1655850 https://reactome.org/PathwayBrowser/#/R-HSA-1655850 Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) TAS Homo sapiens 32395 R-HSA-1801587 https://reactome.org/PathwayBrowser/#/R-HSA-1801587 Expression of CPT1A IEA Homo sapiens 32395 R-HSA-1989745 https://reactome.org/PathwayBrowser/#/R-HSA-1989745 Expression of ACADM TAS Homo sapiens 32395 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 32395 R-HSA-1989747 https://reactome.org/PathwayBrowser/#/R-HSA-1989747 Expression of FHL2 TAS Homo sapiens 32395 R-HSA-1989748 https://reactome.org/PathwayBrowser/#/R-HSA-1989748 Expression of GRHL1 TAS Homo sapiens 32395 R-HSA-1989749 https://reactome.org/PathwayBrowser/#/R-HSA-1989749 Expression of ACOX1 TAS Homo sapiens 32395 R-HSA-1989750 https://reactome.org/PathwayBrowser/#/R-HSA-1989750 Expression of FATP1 (SLC27A1) TAS Homo sapiens 32395 R-HSA-1989751 https://reactome.org/PathwayBrowser/#/R-HSA-1989751 Expression of FABP1 TAS Homo sapiens 32395 R-HSA-1989752 https://reactome.org/PathwayBrowser/#/R-HSA-1989752 Expression of TXNRD1 TAS Homo sapiens 32395 R-HSA-1989753 https://reactome.org/PathwayBrowser/#/R-HSA-1989753 Expression of PEX11A TAS Homo sapiens 32395 R-HSA-1989754 https://reactome.org/PathwayBrowser/#/R-HSA-1989754 Expression of APOA1 TAS Homo sapiens 32395 R-HSA-1989755 https://reactome.org/PathwayBrowser/#/R-HSA-1989755 Expression of CYP4A11 TAS Homo sapiens 32395 R-HSA-1989756 https://reactome.org/PathwayBrowser/#/R-HSA-1989756 Expression of ME1 TAS Homo sapiens 32395 R-HSA-1989757 https://reactome.org/PathwayBrowser/#/R-HSA-1989757 Expression of FADS1 TAS Homo sapiens 32395 R-HSA-1989758 https://reactome.org/PathwayBrowser/#/R-HSA-1989758 Expression of UGT1A9 TAS Homo sapiens 32395 R-HSA-1989759 https://reactome.org/PathwayBrowser/#/R-HSA-1989759 Expression of G0S2 TAS Homo sapiens 32395 R-HSA-1989760 https://reactome.org/PathwayBrowser/#/R-HSA-1989760 Expression of HMGCS2 TAS Homo sapiens 32395 R-HSA-1989761 https://reactome.org/PathwayBrowser/#/R-HSA-1989761 Expression of APOA5 TAS Homo sapiens 32395 R-HSA-1989762 https://reactome.org/PathwayBrowser/#/R-HSA-1989762 Expression of ABCB4 TAS Homo sapiens 32395 R-HSA-1989764 https://reactome.org/PathwayBrowser/#/R-HSA-1989764 Expression of CYP1A1 TAS Homo sapiens 32395 R-HSA-1989765 https://reactome.org/PathwayBrowser/#/R-HSA-1989765 Expression of ABCA1 TAS Homo sapiens 32395 R-HSA-1989767 https://reactome.org/PathwayBrowser/#/R-HSA-1989767 Expression of TRIB3 TAS Homo sapiens 32395 R-HSA-1989768 https://reactome.org/PathwayBrowser/#/R-HSA-1989768 Expression of TIAM2 TAS Homo sapiens 32395 R-HSA-1989770 https://reactome.org/PathwayBrowser/#/R-HSA-1989770 Expression of PLIN2 TAS Homo sapiens 32395 R-HSA-1989771 https://reactome.org/PathwayBrowser/#/R-HSA-1989771 Expression of TNFRSF21 TAS Homo sapiens 32395 R-HSA-1989772 https://reactome.org/PathwayBrowser/#/R-HSA-1989772 Expression of GLIPR1 TAS Homo sapiens 32395 R-HSA-1989773 https://reactome.org/PathwayBrowser/#/R-HSA-1989773 Expression of CPT2 TAS Homo sapiens 32395 R-HSA-1989774 https://reactome.org/PathwayBrowser/#/R-HSA-1989774 Expression of AGT TAS Homo sapiens 32395 R-HSA-1989775 https://reactome.org/PathwayBrowser/#/R-HSA-1989775 Expression of SULT2A1 TAS Homo sapiens 32395 R-HSA-1989776 https://reactome.org/PathwayBrowser/#/R-HSA-1989776 Expression of APOA2 TAS Homo sapiens 32395 R-HSA-1989777 https://reactome.org/PathwayBrowser/#/R-HSA-1989777 Expression of RGL1 TAS Homo sapiens 32395 R-HSA-1989778 https://reactome.org/PathwayBrowser/#/R-HSA-1989778 Expression of ACSL1 TAS Homo sapiens 32395 R-HSA-1989779 https://reactome.org/PathwayBrowser/#/R-HSA-1989779 Expression of ANKRD1 TAS Homo sapiens 32395 R-HSA-2029475 https://reactome.org/PathwayBrowser/#/R-HSA-2029475 Production of AA by iPLA2 upon FCGR activation TAS Homo sapiens 32395 R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 32395 R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 32395 R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 32395 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 32395 R-HSA-2161794 https://reactome.org/PathwayBrowser/#/R-HSA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 TAS Homo sapiens 32395 R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) TAS Homo sapiens 32395 R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 32395 R-HSA-2161890 https://reactome.org/PathwayBrowser/#/R-HSA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) TAS Homo sapiens 32395 R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) TAS Homo sapiens 32395 R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 32395 R-HSA-2161948 https://reactome.org/PathwayBrowser/#/R-HSA-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 TAS Homo sapiens 32395 R-HSA-2161950 https://reactome.org/PathwayBrowser/#/R-HSA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B TAS Homo sapiens 32395 R-HSA-2161951 https://reactome.org/PathwayBrowser/#/R-HSA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 TAS Homo sapiens 32395 R-HSA-2161964 https://reactome.org/PathwayBrowser/#/R-HSA-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 TAS Homo sapiens 32395 R-HSA-2162002 https://reactome.org/PathwayBrowser/#/R-HSA-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B TAS Homo sapiens 32395 R-HSA-2309787 https://reactome.org/PathwayBrowser/#/R-HSA-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 TAS Homo sapiens 32395 R-HSA-265296 https://reactome.org/PathwayBrowser/#/R-HSA-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 TAS Homo sapiens 32395 R-HSA-400143 https://reactome.org/PathwayBrowser/#/R-HSA-400143 Fatty acid ligands activate PPARA TAS Homo sapiens 32395 R-HSA-426043 https://reactome.org/PathwayBrowser/#/R-HSA-426043 2-AG hydrolysis to arachidonate by MAGL TAS Homo sapiens 32395 R-HSA-428990 https://reactome.org/PathwayBrowser/#/R-HSA-428990 Arachidonate diffuses across the ER membrane TAS Homo sapiens 32395 R-HSA-548843 https://reactome.org/PathwayBrowser/#/R-HSA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA TAS Homo sapiens 32395 R-HSA-5602242 https://reactome.org/PathwayBrowser/#/R-HSA-5602242 Defective CYP2U1 does not omega-hydroxylate ARA TAS Homo sapiens 32395 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 32395 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 32395 R-HSA-5668629 https://reactome.org/PathwayBrowser/#/R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP TAS Homo sapiens 32395 R-HSA-5693742 https://reactome.org/PathwayBrowser/#/R-HSA-5693742 FAAH hydrolyses AEA to AA and ETA TAS Homo sapiens 32395 R-HSA-5693751 https://reactome.org/PathwayBrowser/#/R-HSA-5693751 FAAH2 hydrolyses AEA to AA and ETA TAS Homo sapiens 32395 R-HSA-5694462 https://reactome.org/PathwayBrowser/#/R-HSA-5694462 ABHD6,12 hydrolyse 3AG TAS Homo sapiens 32395 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 32395 R-HSA-879724 https://reactome.org/PathwayBrowser/#/R-HSA-879724 Expression of PPARA IEA Homo sapiens 32395 R-HSA-9626848 https://reactome.org/PathwayBrowser/#/R-HSA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex TAS Homo sapiens 32395 R-MMU-111883 https://reactome.org/PathwayBrowser/#/R-MMU-111883 Hydrolysis of phosphatidylcholine IEA Mus musculus 32395 R-MMU-140355 https://reactome.org/PathwayBrowser/#/R-MMU-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Mus musculus 32395 R-MMU-2029475 https://reactome.org/PathwayBrowser/#/R-MMU-2029475 Production of AA by iPLA2 upon FCGR activation IEA Mus musculus 32395 R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 32395 R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 32395 R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 32395 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 32395 R-MMU-2161794 https://reactome.org/PathwayBrowser/#/R-MMU-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Mus musculus 32395 R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Mus musculus 32395 R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 32395 R-MMU-2161890 https://reactome.org/PathwayBrowser/#/R-MMU-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Mus musculus 32395 R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Mus musculus 32395 R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 32395 R-MMU-2161948 https://reactome.org/PathwayBrowser/#/R-MMU-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Mus musculus 32395 R-MMU-2161950 https://reactome.org/PathwayBrowser/#/R-MMU-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Mus musculus 32395 R-MMU-2161951 https://reactome.org/PathwayBrowser/#/R-MMU-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Mus musculus 32395 R-MMU-2161964 https://reactome.org/PathwayBrowser/#/R-MMU-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Mus musculus 32395 R-MMU-2162002 https://reactome.org/PathwayBrowser/#/R-MMU-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Mus musculus 32395 R-MMU-2309787 https://reactome.org/PathwayBrowser/#/R-MMU-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Mus musculus 32395 R-MMU-265296 https://reactome.org/PathwayBrowser/#/R-MMU-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Mus musculus 32395 R-MMU-400143 https://reactome.org/PathwayBrowser/#/R-MMU-400143 Fatty acid ligands activate PPARA IEA Mus musculus 32395 R-MMU-426043 https://reactome.org/PathwayBrowser/#/R-MMU-426043 2-AG hydrolysis to arachidonate by MAGL IEA Mus musculus 32395 R-MMU-548843 https://reactome.org/PathwayBrowser/#/R-MMU-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Mus musculus 32395 R-MMU-5668629 https://reactome.org/PathwayBrowser/#/R-MMU-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Mus musculus 32395 R-MMU-5693742 https://reactome.org/PathwayBrowser/#/R-MMU-5693742 FAAH hydrolyses AEA to AA and ETA IEA Mus musculus 32395 R-MMU-5694462 https://reactome.org/PathwayBrowser/#/R-MMU-5694462 ABHD6,12 hydrolyse 3AG IEA Mus musculus 32395 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 32395 R-MMU-9626848 https://reactome.org/PathwayBrowser/#/R-MMU-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Mus musculus 32395 R-PFA-426043 https://reactome.org/PathwayBrowser/#/R-PFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Plasmodium falciparum 32395 R-RNO-111883 https://reactome.org/PathwayBrowser/#/R-RNO-111883 Hydrolysis of phosphatidylcholine IEA Rattus norvegicus 32395 R-RNO-140355 https://reactome.org/PathwayBrowser/#/R-RNO-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Rattus norvegicus 32395 R-RNO-2029475 https://reactome.org/PathwayBrowser/#/R-RNO-2029475 Production of AA by iPLA2 upon FCGR activation IEA Rattus norvegicus 32395 R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 32395 R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 32395 R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 32395 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 32395 R-RNO-2161794 https://reactome.org/PathwayBrowser/#/R-RNO-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Rattus norvegicus 32395 R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Rattus norvegicus 32395 R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 32395 R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus 32395 R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Rattus norvegicus 32395 R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 32395 R-RNO-2161948 https://reactome.org/PathwayBrowser/#/R-RNO-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Rattus norvegicus 32395 R-RNO-2161950 https://reactome.org/PathwayBrowser/#/R-RNO-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Rattus norvegicus 32395 R-RNO-2161951 https://reactome.org/PathwayBrowser/#/R-RNO-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Rattus norvegicus 32395 R-RNO-2161964 https://reactome.org/PathwayBrowser/#/R-RNO-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Rattus norvegicus 32395 R-RNO-2162002 https://reactome.org/PathwayBrowser/#/R-RNO-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Rattus norvegicus 32395 R-RNO-2309787 https://reactome.org/PathwayBrowser/#/R-RNO-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Rattus norvegicus 32395 R-RNO-265296 https://reactome.org/PathwayBrowser/#/R-RNO-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Rattus norvegicus 32395 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus 32395 R-RNO-426043 https://reactome.org/PathwayBrowser/#/R-RNO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Rattus norvegicus 32395 R-RNO-548843 https://reactome.org/PathwayBrowser/#/R-RNO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Rattus norvegicus 32395 R-RNO-5668629 https://reactome.org/PathwayBrowser/#/R-RNO-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Rattus norvegicus 32395 R-RNO-5693742 https://reactome.org/PathwayBrowser/#/R-RNO-5693742 FAAH hydrolyses AEA to AA and ETA IEA Rattus norvegicus 32395 R-RNO-5694462 https://reactome.org/PathwayBrowser/#/R-RNO-5694462 ABHD6,12 hydrolyse 3AG IEA Rattus norvegicus 32395 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 32395 R-RNO-9626848 https://reactome.org/PathwayBrowser/#/R-RNO-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Rattus norvegicus 32395 R-SCE-111883 https://reactome.org/PathwayBrowser/#/R-SCE-111883 Hydrolysis of phosphatidylcholine IEA Saccharomyces cerevisiae 32395 R-SCE-426043 https://reactome.org/PathwayBrowser/#/R-SCE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Saccharomyces cerevisiae 32395 R-SCE-548843 https://reactome.org/PathwayBrowser/#/R-SCE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Saccharomyces cerevisiae 32395 R-SCE-5694462 https://reactome.org/PathwayBrowser/#/R-SCE-5694462 ABHD6,12 hydrolyse 3AG IEA Saccharomyces cerevisiae 32395 R-SPO-111883 https://reactome.org/PathwayBrowser/#/R-SPO-111883 Hydrolysis of phosphatidylcholine IEA Schizosaccharomyces pombe 32395 R-SPO-426043 https://reactome.org/PathwayBrowser/#/R-SPO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Schizosaccharomyces pombe 32395 R-SPO-548843 https://reactome.org/PathwayBrowser/#/R-SPO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Schizosaccharomyces pombe 32395 R-SSC-111883 https://reactome.org/PathwayBrowser/#/R-SSC-111883 Hydrolysis of phosphatidylcholine IEA Sus scrofa 32395 R-SSC-140355 https://reactome.org/PathwayBrowser/#/R-SSC-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Sus scrofa 32395 R-SSC-2029475 https://reactome.org/PathwayBrowser/#/R-SSC-2029475 Production of AA by iPLA2 upon FCGR activation IEA Sus scrofa 32395 R-SSC-211904 https://reactome.org/PathwayBrowser/#/R-SSC-211904 CYP4F12 18-hydroxylates ARA IEA Sus scrofa 32395 R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa 32395 R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa 32395 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 32395 R-SSC-2161794 https://reactome.org/PathwayBrowser/#/R-SSC-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Sus scrofa 32395 R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Sus scrofa 32395 R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa 32395 R-SSC-2161890 https://reactome.org/PathwayBrowser/#/R-SSC-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Sus scrofa 32395 R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Sus scrofa 32395 R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa 32395 R-SSC-2161948 https://reactome.org/PathwayBrowser/#/R-SSC-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Sus scrofa 32395 R-SSC-2161950 https://reactome.org/PathwayBrowser/#/R-SSC-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Sus scrofa 32395 R-SSC-2161951 https://reactome.org/PathwayBrowser/#/R-SSC-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Sus scrofa 32395 R-SSC-2161964 https://reactome.org/PathwayBrowser/#/R-SSC-2161964 Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 IEA Sus scrofa 32395 R-SSC-2162002 https://reactome.org/PathwayBrowser/#/R-SSC-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Sus scrofa 32395 R-SSC-2309787 https://reactome.org/PathwayBrowser/#/R-SSC-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Sus scrofa 32395 R-SSC-265296 https://reactome.org/PathwayBrowser/#/R-SSC-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Sus scrofa 32395 R-SSC-426043 https://reactome.org/PathwayBrowser/#/R-SSC-426043 2-AG hydrolysis to arachidonate by MAGL IEA Sus scrofa 32395 R-SSC-548843 https://reactome.org/PathwayBrowser/#/R-SSC-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Sus scrofa 32395 R-SSC-5668629 https://reactome.org/PathwayBrowser/#/R-SSC-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Sus scrofa 32395 R-SSC-5693742 https://reactome.org/PathwayBrowser/#/R-SSC-5693742 FAAH hydrolyses AEA to AA and ETA IEA Sus scrofa 32395 R-SSC-5694462 https://reactome.org/PathwayBrowser/#/R-SSC-5694462 ABHD6,12 hydrolyse 3AG IEA Sus scrofa 32395 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 32395 R-SSC-9626848 https://reactome.org/PathwayBrowser/#/R-SSC-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Sus scrofa 32395 R-XTR-111883 https://reactome.org/PathwayBrowser/#/R-XTR-111883 Hydrolysis of phosphatidylcholine IEA Xenopus tropicalis 32395 R-XTR-140355 https://reactome.org/PathwayBrowser/#/R-XTR-140355 Arachidonic acid is oxidised to PGG2 by PTGS1 IEA Xenopus tropicalis 32395 R-XTR-2029475 https://reactome.org/PathwayBrowser/#/R-XTR-2029475 Production of AA by iPLA2 upon FCGR activation IEA Xenopus tropicalis 32395 R-XTR-211904 https://reactome.org/PathwayBrowser/#/R-XTR-211904 CYP4F12 18-hydroxylates ARA IEA Xenopus tropicalis 32395 R-XTR-211924 https://reactome.org/PathwayBrowser/#/R-XTR-211924 CYP4B1 12-hydroxylates ARA IEA Xenopus tropicalis 32395 R-XTR-211960 https://reactome.org/PathwayBrowser/#/R-XTR-211960 CYP2U1 19-hydroxylates ARA IEA Xenopus tropicalis 32395 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 32395 R-XTR-2161814 https://reactome.org/PathwayBrowser/#/R-XTR-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Xenopus tropicalis 32395 R-XTR-2161890 https://reactome.org/PathwayBrowser/#/R-XTR-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Xenopus tropicalis 32395 R-XTR-2161899 https://reactome.org/PathwayBrowser/#/R-XTR-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Xenopus tropicalis 32395 R-XTR-2161940 https://reactome.org/PathwayBrowser/#/R-XTR-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Xenopus tropicalis 32395 R-XTR-2161950 https://reactome.org/PathwayBrowser/#/R-XTR-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Xenopus tropicalis 32395 R-XTR-2161951 https://reactome.org/PathwayBrowser/#/R-XTR-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Xenopus tropicalis 32395 R-XTR-2162002 https://reactome.org/PathwayBrowser/#/R-XTR-2162002 Arachidonic acid is oxidised to 15S-HpETE by ALOX15/15B IEA Xenopus tropicalis 32395 R-XTR-2309787 https://reactome.org/PathwayBrowser/#/R-XTR-2309787 Arachidonic acid is oxidised to PGG2 by PTGS2 IEA Xenopus tropicalis 32395 R-XTR-265296 https://reactome.org/PathwayBrowser/#/R-XTR-265296 Arachidonic acid is oxidised to 5S-HpETE by ALOX5 IEA Xenopus tropicalis 32395 R-XTR-426043 https://reactome.org/PathwayBrowser/#/R-XTR-426043 2-AG hydrolysis to arachidonate by MAGL IEA Xenopus tropicalis 32395 R-XTR-548843 https://reactome.org/PathwayBrowser/#/R-XTR-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Xenopus tropicalis 32395 R-XTR-5668629 https://reactome.org/PathwayBrowser/#/R-XTR-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Xenopus tropicalis 32395 R-XTR-5693742 https://reactome.org/PathwayBrowser/#/R-XTR-5693742 FAAH hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 32395 R-XTR-5693751 https://reactome.org/PathwayBrowser/#/R-XTR-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 32395 R-XTR-5694462 https://reactome.org/PathwayBrowser/#/R-XTR-5694462 ABHD6,12 hydrolyse 3AG IEA Xenopus tropicalis 32395 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 32395 R-XTR-9626848 https://reactome.org/PathwayBrowser/#/R-XTR-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Xenopus tropicalis 32513 R-BTA-352174 https://reactome.org/PathwayBrowser/#/R-BTA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Bos taurus 32513 R-BTA-352182 https://reactome.org/PathwayBrowser/#/R-BTA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Bos taurus 32513 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 32513 R-BTA-352232 https://reactome.org/PathwayBrowser/#/R-BTA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Bos taurus 32513 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 32513 R-BTA-428007 https://reactome.org/PathwayBrowser/#/R-BTA-428007 Proton-coupled histidine and di-peptide cotransport IEA Bos taurus 32513 R-BTA-6786245 https://reactome.org/PathwayBrowser/#/R-BTA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Bos taurus 32513 R-BTA-70899 https://reactome.org/PathwayBrowser/#/R-BTA-70899 histidine => urocanate + NH4+ IEA Bos taurus 32513 R-BTA-8932851 https://reactome.org/PathwayBrowser/#/R-BTA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Bos taurus 32513 R-BTA-8959781 https://reactome.org/PathwayBrowser/#/R-BTA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Bos taurus 32513 R-BTA-977301 https://reactome.org/PathwayBrowser/#/R-BTA-977301 Histidine is decarboxylated to histamine IEA Bos taurus 32513 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 32513 R-CEL-70899 https://reactome.org/PathwayBrowser/#/R-CEL-70899 histidine => urocanate + NH4+ IEA Caenorhabditis elegans 32513 R-CEL-8932851 https://reactome.org/PathwayBrowser/#/R-CEL-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Caenorhabditis elegans 32513 R-CEL-8959781 https://reactome.org/PathwayBrowser/#/R-CEL-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Caenorhabditis elegans 32513 R-CFA-352174 https://reactome.org/PathwayBrowser/#/R-CFA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Canis familiaris 32513 R-CFA-352182 https://reactome.org/PathwayBrowser/#/R-CFA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Canis familiaris 32513 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 32513 R-CFA-352232 https://reactome.org/PathwayBrowser/#/R-CFA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Canis familiaris 32513 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 32513 R-CFA-428007 https://reactome.org/PathwayBrowser/#/R-CFA-428007 Proton-coupled histidine and di-peptide cotransport IEA Canis familiaris 32513 R-CFA-6786245 https://reactome.org/PathwayBrowser/#/R-CFA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Canis familiaris 32513 R-CFA-70899 https://reactome.org/PathwayBrowser/#/R-CFA-70899 histidine => urocanate + NH4+ IEA Canis familiaris 32513 R-CFA-8932851 https://reactome.org/PathwayBrowser/#/R-CFA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Canis familiaris 32513 R-CFA-8959781 https://reactome.org/PathwayBrowser/#/R-CFA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Canis familiaris 32513 R-CFA-977301 https://reactome.org/PathwayBrowser/#/R-CFA-977301 Histidine is decarboxylated to histamine IEA Canis familiaris 32513 R-DDI-70899 https://reactome.org/PathwayBrowser/#/R-DDI-70899 histidine => urocanate + NH4+ IEA Dictyostelium discoideum 32513 R-DME-352174 https://reactome.org/PathwayBrowser/#/R-DME-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Drosophila melanogaster 32513 R-DME-352182 https://reactome.org/PathwayBrowser/#/R-DME-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Drosophila melanogaster 32513 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 32513 R-DME-352232 https://reactome.org/PathwayBrowser/#/R-DME-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Drosophila melanogaster 32513 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 32513 R-DME-8959781 https://reactome.org/PathwayBrowser/#/R-DME-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Drosophila melanogaster 32513 R-DME-977301 https://reactome.org/PathwayBrowser/#/R-DME-977301 Histidine is decarboxylated to histamine IEA Drosophila melanogaster 32513 R-DRE-352182 https://reactome.org/PathwayBrowser/#/R-DRE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Danio rerio 32513 R-DRE-70899 https://reactome.org/PathwayBrowser/#/R-DRE-70899 histidine => urocanate + NH4+ IEA Danio rerio 32513 R-DRE-8959781 https://reactome.org/PathwayBrowser/#/R-DRE-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Danio rerio 32513 R-GGA-352174 https://reactome.org/PathwayBrowser/#/R-GGA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Gallus gallus 32513 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 32513 R-GGA-428007 https://reactome.org/PathwayBrowser/#/R-GGA-428007 Proton-coupled histidine and di-peptide cotransport IEA Gallus gallus 32513 R-GGA-6786245 https://reactome.org/PathwayBrowser/#/R-GGA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Gallus gallus 32513 R-GGA-70899 https://reactome.org/PathwayBrowser/#/R-GGA-70899 histidine => urocanate + NH4+ IEA Gallus gallus 32513 R-GGA-8932851 https://reactome.org/PathwayBrowser/#/R-GGA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Gallus gallus 32513 R-GGA-8959781 https://reactome.org/PathwayBrowser/#/R-GGA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Gallus gallus 32513 R-GGA-977301 https://reactome.org/PathwayBrowser/#/R-GGA-977301 Histidine is decarboxylated to histamine IEA Gallus gallus 32513 R-HSA-352174 https://reactome.org/PathwayBrowser/#/R-HSA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine TAS Homo sapiens 32513 R-HSA-352182 https://reactome.org/PathwayBrowser/#/R-HSA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine TAS Homo sapiens 32513 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 32513 R-HSA-352232 https://reactome.org/PathwayBrowser/#/R-HSA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol TAS Homo sapiens 32513 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 32513 R-HSA-379844 https://reactome.org/PathwayBrowser/#/R-HSA-379844 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 32513 R-HSA-380234 https://reactome.org/PathwayBrowser/#/R-HSA-380234 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 32513 R-HSA-428007 https://reactome.org/PathwayBrowser/#/R-HSA-428007 Proton-coupled histidine and di-peptide cotransport TAS Homo sapiens 32513 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 32513 R-HSA-6786245 https://reactome.org/PathwayBrowser/#/R-HSA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN TAS Homo sapiens 32513 R-HSA-70899 https://reactome.org/PathwayBrowser/#/R-HSA-70899 histidine => urocanate + NH4+ TAS Homo sapiens 32513 R-HSA-8932851 https://reactome.org/PathwayBrowser/#/R-HSA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol TAS Homo sapiens 32513 R-HSA-8959781 https://reactome.org/PathwayBrowser/#/R-HSA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix TAS Homo sapiens 32513 R-HSA-977301 https://reactome.org/PathwayBrowser/#/R-HSA-977301 Histidine is decarboxylated to histamine TAS Homo sapiens 32513 R-MMU-352174 https://reactome.org/PathwayBrowser/#/R-MMU-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Mus musculus 32513 R-MMU-352182 https://reactome.org/PathwayBrowser/#/R-MMU-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Mus musculus 32513 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 32513 R-MMU-352232 https://reactome.org/PathwayBrowser/#/R-MMU-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Mus musculus 32513 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 32513 R-MMU-428007 https://reactome.org/PathwayBrowser/#/R-MMU-428007 Proton-coupled histidine and di-peptide cotransport IEA Mus musculus 32513 R-MMU-6786245 https://reactome.org/PathwayBrowser/#/R-MMU-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Mus musculus 32513 R-MMU-70899 https://reactome.org/PathwayBrowser/#/R-MMU-70899 histidine => urocanate + NH4+ IEA Mus musculus 32513 R-MMU-8932851 https://reactome.org/PathwayBrowser/#/R-MMU-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Mus musculus 32513 R-MMU-8959781 https://reactome.org/PathwayBrowser/#/R-MMU-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Mus musculus 32513 R-MMU-977301 https://reactome.org/PathwayBrowser/#/R-MMU-977301 Histidine is decarboxylated to histamine IEA Mus musculus 32513 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 32513 R-RNO-352174 https://reactome.org/PathwayBrowser/#/R-RNO-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Rattus norvegicus 32513 R-RNO-352182 https://reactome.org/PathwayBrowser/#/R-RNO-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Rattus norvegicus 32513 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 32513 R-RNO-352232 https://reactome.org/PathwayBrowser/#/R-RNO-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Rattus norvegicus 32513 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 32513 R-RNO-428007 https://reactome.org/PathwayBrowser/#/R-RNO-428007 Proton-coupled histidine and di-peptide cotransport IEA Rattus norvegicus 32513 R-RNO-6786245 https://reactome.org/PathwayBrowser/#/R-RNO-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Rattus norvegicus 32513 R-RNO-70899 https://reactome.org/PathwayBrowser/#/R-RNO-70899 histidine => urocanate + NH4+ IEA Rattus norvegicus 32513 R-RNO-8932851 https://reactome.org/PathwayBrowser/#/R-RNO-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Rattus norvegicus 32513 R-RNO-8959781 https://reactome.org/PathwayBrowser/#/R-RNO-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Rattus norvegicus 32513 R-RNO-977301 https://reactome.org/PathwayBrowser/#/R-RNO-977301 Histidine is decarboxylated to histamine IEA Rattus norvegicus 32513 R-SCE-352174 https://reactome.org/PathwayBrowser/#/R-SCE-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Saccharomyces cerevisiae 32513 R-SCE-352182 https://reactome.org/PathwayBrowser/#/R-SCE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Saccharomyces cerevisiae 32513 R-SCE-428007 https://reactome.org/PathwayBrowser/#/R-SCE-428007 Proton-coupled histidine and di-peptide cotransport IEA Saccharomyces cerevisiae 32513 R-SCE-8932851 https://reactome.org/PathwayBrowser/#/R-SCE-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Saccharomyces cerevisiae 32513 R-SPO-428007 https://reactome.org/PathwayBrowser/#/R-SPO-428007 Proton-coupled histidine and di-peptide cotransport IEA Schizosaccharomyces pombe 32513 R-SPO-8932851 https://reactome.org/PathwayBrowser/#/R-SPO-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Schizosaccharomyces pombe 32513 R-SSC-352174 https://reactome.org/PathwayBrowser/#/R-SSC-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Sus scrofa 32513 R-SSC-352182 https://reactome.org/PathwayBrowser/#/R-SSC-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Sus scrofa 32513 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 32513 R-SSC-352232 https://reactome.org/PathwayBrowser/#/R-SSC-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Sus scrofa 32513 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 32513 R-SSC-428007 https://reactome.org/PathwayBrowser/#/R-SSC-428007 Proton-coupled histidine and di-peptide cotransport IEA Sus scrofa 32513 R-SSC-6786245 https://reactome.org/PathwayBrowser/#/R-SSC-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Sus scrofa 32513 R-SSC-70899 https://reactome.org/PathwayBrowser/#/R-SSC-70899 histidine => urocanate + NH4+ IEA Sus scrofa 32513 R-SSC-8932851 https://reactome.org/PathwayBrowser/#/R-SSC-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Sus scrofa 32513 R-SSC-977301 https://reactome.org/PathwayBrowser/#/R-SSC-977301 Histidine is decarboxylated to histamine IEA Sus scrofa 32513 R-XTR-352174 https://reactome.org/PathwayBrowser/#/R-XTR-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Xenopus tropicalis 32513 R-XTR-352182 https://reactome.org/PathwayBrowser/#/R-XTR-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Xenopus tropicalis 32513 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 32513 R-XTR-352232 https://reactome.org/PathwayBrowser/#/R-XTR-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Xenopus tropicalis 32513 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 32513 R-XTR-428007 https://reactome.org/PathwayBrowser/#/R-XTR-428007 Proton-coupled histidine and di-peptide cotransport IEA Xenopus tropicalis 32513 R-XTR-6786245 https://reactome.org/PathwayBrowser/#/R-XTR-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Xenopus tropicalis 32513 R-XTR-70899 https://reactome.org/PathwayBrowser/#/R-XTR-70899 histidine => urocanate + NH4+ IEA Xenopus tropicalis 32513 R-XTR-8932851 https://reactome.org/PathwayBrowser/#/R-XTR-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Xenopus tropicalis 32513 R-XTR-8959781 https://reactome.org/PathwayBrowser/#/R-XTR-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Xenopus tropicalis 32513 R-XTR-977301 https://reactome.org/PathwayBrowser/#/R-XTR-977301 Histidine is decarboxylated to histamine IEA Xenopus tropicalis 32544 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Bos taurus 32544 R-BTA-8876312 https://reactome.org/PathwayBrowser/#/R-BTA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Bos taurus 32544 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Caenorhabditis elegans 32544 R-CEL-8869603 https://reactome.org/PathwayBrowser/#/R-CEL-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Caenorhabditis elegans 32544 R-CEL-8876312 https://reactome.org/PathwayBrowser/#/R-CEL-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Caenorhabditis elegans 32544 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Canis familiaris 32544 R-CFA-8869603 https://reactome.org/PathwayBrowser/#/R-CFA-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Canis familiaris 32544 R-CFA-8876312 https://reactome.org/PathwayBrowser/#/R-CFA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Canis familiaris 32544 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Drosophila melanogaster 32544 R-DME-8869603 https://reactome.org/PathwayBrowser/#/R-DME-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Drosophila melanogaster 32544 R-DME-8876312 https://reactome.org/PathwayBrowser/#/R-DME-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Drosophila melanogaster 32544 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Danio rerio 32544 R-DRE-8876312 https://reactome.org/PathwayBrowser/#/R-DRE-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Danio rerio 32544 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Gallus gallus 32544 R-GGA-8869603 https://reactome.org/PathwayBrowser/#/R-GGA-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Gallus gallus 32544 R-GGA-8876312 https://reactome.org/PathwayBrowser/#/R-GGA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Gallus gallus 32544 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol TAS Homo sapiens 32544 R-HSA-8869603 https://reactome.org/PathwayBrowser/#/R-HSA-8869603 SLC22A13 transports NCA from extracellular region to cytosol TAS Homo sapiens 32544 R-HSA-8876312 https://reactome.org/PathwayBrowser/#/R-HSA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol TAS Homo sapiens 32544 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Mus musculus 32544 R-MMU-8869603 https://reactome.org/PathwayBrowser/#/R-MMU-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Mus musculus 32544 R-MMU-8876312 https://reactome.org/PathwayBrowser/#/R-MMU-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Mus musculus 32544 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Rattus norvegicus 32544 R-RNO-8869603 https://reactome.org/PathwayBrowser/#/R-RNO-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Rattus norvegicus 32544 R-RNO-8876312 https://reactome.org/PathwayBrowser/#/R-RNO-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Rattus norvegicus 32544 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Sus scrofa 32544 R-SSC-8869603 https://reactome.org/PathwayBrowser/#/R-SSC-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Sus scrofa 32544 R-SSC-8876312 https://reactome.org/PathwayBrowser/#/R-SSC-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Sus scrofa 32544 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Xenopus tropicalis 32544 R-XTR-8869603 https://reactome.org/PathwayBrowser/#/R-XTR-8869603 SLC22A13 transports NCA from extracellular region to cytosol IEA Xenopus tropicalis 32544 R-XTR-8876312 https://reactome.org/PathwayBrowser/#/R-XTR-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Xenopus tropicalis 32551 R-BTA-3076905 https://reactome.org/PathwayBrowser/#/R-BTA-3076905 Extracellular BTD hydrolyses BCTN IEA Bos taurus 32551 R-BTA-352136 https://reactome.org/PathwayBrowser/#/R-BTA-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Bos taurus 32551 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 32551 R-BTA-375770 https://reactome.org/PathwayBrowser/#/R-BTA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Bos taurus 32551 R-BTA-375776 https://reactome.org/PathwayBrowser/#/R-BTA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Bos taurus 32551 R-BTA-379432 https://reactome.org/PathwayBrowser/#/R-BTA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Bos taurus 32551 R-BTA-4167509 https://reactome.org/PathwayBrowser/#/R-BTA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Bos taurus 32551 R-BTA-5690319 https://reactome.org/PathwayBrowser/#/R-BTA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Bos taurus 32551 R-BTA-70938 https://reactome.org/PathwayBrowser/#/R-BTA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Bos taurus 32551 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 32551 R-BTA-8932851 https://reactome.org/PathwayBrowser/#/R-BTA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Bos taurus 32551 R-BTA-8959781 https://reactome.org/PathwayBrowser/#/R-BTA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Bos taurus 32551 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 32551 R-CEL-5690319 https://reactome.org/PathwayBrowser/#/R-CEL-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Caenorhabditis elegans 32551 R-CEL-70938 https://reactome.org/PathwayBrowser/#/R-CEL-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Caenorhabditis elegans 32551 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 32551 R-CEL-8932851 https://reactome.org/PathwayBrowser/#/R-CEL-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Caenorhabditis elegans 32551 R-CEL-8959781 https://reactome.org/PathwayBrowser/#/R-CEL-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Caenorhabditis elegans 32551 R-CFA-3076905 https://reactome.org/PathwayBrowser/#/R-CFA-3076905 Extracellular BTD hydrolyses BCTN IEA Canis familiaris 32551 R-CFA-352136 https://reactome.org/PathwayBrowser/#/R-CFA-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Canis familiaris 32551 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 32551 R-CFA-375768 https://reactome.org/PathwayBrowser/#/R-CFA-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Canis familiaris 32551 R-CFA-375770 https://reactome.org/PathwayBrowser/#/R-CFA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Canis familiaris 32551 R-CFA-375776 https://reactome.org/PathwayBrowser/#/R-CFA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Canis familiaris 32551 R-CFA-375790 https://reactome.org/PathwayBrowser/#/R-CFA-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Canis familiaris 32551 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 32551 R-CFA-379432 https://reactome.org/PathwayBrowser/#/R-CFA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Canis familiaris 32551 R-CFA-4167509 https://reactome.org/PathwayBrowser/#/R-CFA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Canis familiaris 32551 R-CFA-420739 https://reactome.org/PathwayBrowser/#/R-CFA-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Canis familiaris 32551 R-CFA-5690319 https://reactome.org/PathwayBrowser/#/R-CFA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Canis familiaris 32551 R-CFA-70938 https://reactome.org/PathwayBrowser/#/R-CFA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Canis familiaris 32551 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 32551 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 32551 R-CFA-8932851 https://reactome.org/PathwayBrowser/#/R-CFA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Canis familiaris 32551 R-CFA-8959781 https://reactome.org/PathwayBrowser/#/R-CFA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Canis familiaris 32551 R-DDI-3076905 https://reactome.org/PathwayBrowser/#/R-DDI-3076905 Extracellular BTD hydrolyses BCTN IEA Dictyostelium discoideum 32551 R-DDI-375768 https://reactome.org/PathwayBrowser/#/R-DDI-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 32551 R-DDI-375770 https://reactome.org/PathwayBrowser/#/R-DDI-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 32551 R-DDI-375776 https://reactome.org/PathwayBrowser/#/R-DDI-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 32551 R-DDI-375790 https://reactome.org/PathwayBrowser/#/R-DDI-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 32551 R-DDI-4167509 https://reactome.org/PathwayBrowser/#/R-DDI-4167509 Mitochondrial BTD hydrolyses BCTN IEA Dictyostelium discoideum 32551 R-DDI-5690319 https://reactome.org/PathwayBrowser/#/R-DDI-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Dictyostelium discoideum 32551 R-DDI-70938 https://reactome.org/PathwayBrowser/#/R-DDI-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Dictyostelium discoideum 32551 R-DME-3076905 https://reactome.org/PathwayBrowser/#/R-DME-3076905 Extracellular BTD hydrolyses BCTN IEA Drosophila melanogaster 32551 R-DME-352136 https://reactome.org/PathwayBrowser/#/R-DME-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Drosophila melanogaster 32551 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 32551 R-DME-375768 https://reactome.org/PathwayBrowser/#/R-DME-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 32551 R-DME-375770 https://reactome.org/PathwayBrowser/#/R-DME-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 32551 R-DME-375776 https://reactome.org/PathwayBrowser/#/R-DME-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 32551 R-DME-375790 https://reactome.org/PathwayBrowser/#/R-DME-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 32551 R-DME-379432 https://reactome.org/PathwayBrowser/#/R-DME-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Drosophila melanogaster 32551 R-DME-4167509 https://reactome.org/PathwayBrowser/#/R-DME-4167509 Mitochondrial BTD hydrolyses BCTN IEA Drosophila melanogaster 32551 R-DME-5690319 https://reactome.org/PathwayBrowser/#/R-DME-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Drosophila melanogaster 32551 R-DME-70938 https://reactome.org/PathwayBrowser/#/R-DME-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Drosophila melanogaster 32551 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 32551 R-DME-8959781 https://reactome.org/PathwayBrowser/#/R-DME-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Drosophila melanogaster 32551 R-DRE-3076905 https://reactome.org/PathwayBrowser/#/R-DRE-3076905 Extracellular BTD hydrolyses BCTN IEA Danio rerio 32551 R-DRE-375768 https://reactome.org/PathwayBrowser/#/R-DRE-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Danio rerio 32551 R-DRE-375776 https://reactome.org/PathwayBrowser/#/R-DRE-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Danio rerio 32551 R-DRE-375790 https://reactome.org/PathwayBrowser/#/R-DRE-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Danio rerio 32551 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 32551 R-DRE-4167509 https://reactome.org/PathwayBrowser/#/R-DRE-4167509 Mitochondrial BTD hydrolyses BCTN IEA Danio rerio 32551 R-DRE-420739 https://reactome.org/PathwayBrowser/#/R-DRE-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Danio rerio 32551 R-DRE-5690319 https://reactome.org/PathwayBrowser/#/R-DRE-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Danio rerio 32551 R-DRE-70938 https://reactome.org/PathwayBrowser/#/R-DRE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Danio rerio 32551 R-DRE-8959781 https://reactome.org/PathwayBrowser/#/R-DRE-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Danio rerio 32551 R-GGA-3076905 https://reactome.org/PathwayBrowser/#/R-GGA-3076905 Extracellular BTD hydrolyses BCTN IEA Gallus gallus 32551 R-GGA-352136 https://reactome.org/PathwayBrowser/#/R-GGA-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Gallus gallus 32551 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 32551 R-GGA-375768 https://reactome.org/PathwayBrowser/#/R-GGA-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Gallus gallus 32551 R-GGA-375770 https://reactome.org/PathwayBrowser/#/R-GGA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Gallus gallus 32551 R-GGA-375776 https://reactome.org/PathwayBrowser/#/R-GGA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Gallus gallus 32551 R-GGA-375790 https://reactome.org/PathwayBrowser/#/R-GGA-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Gallus gallus 32551 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 32551 R-GGA-379432 https://reactome.org/PathwayBrowser/#/R-GGA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Gallus gallus 32551 R-GGA-4167509 https://reactome.org/PathwayBrowser/#/R-GGA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Gallus gallus 32551 R-GGA-420739 https://reactome.org/PathwayBrowser/#/R-GGA-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Gallus gallus 32551 R-GGA-5690319 https://reactome.org/PathwayBrowser/#/R-GGA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Gallus gallus 32551 R-GGA-70938 https://reactome.org/PathwayBrowser/#/R-GGA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Gallus gallus 32551 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 32551 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 32551 R-GGA-8932851 https://reactome.org/PathwayBrowser/#/R-GGA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Gallus gallus 32551 R-GGA-8959781 https://reactome.org/PathwayBrowser/#/R-GGA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Gallus gallus 32551 R-HSA-3076905 https://reactome.org/PathwayBrowser/#/R-HSA-3076905 Extracellular BTD hydrolyses BCTN TAS Homo sapiens 32551 R-HSA-352136 https://reactome.org/PathwayBrowser/#/R-HSA-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine TAS Homo sapiens 32551 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 32551 R-HSA-375768 https://reactome.org/PathwayBrowser/#/R-HSA-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids TAS Homo sapiens 32551 R-HSA-375770 https://reactome.org/PathwayBrowser/#/R-HSA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids TAS Homo sapiens 32551 R-HSA-375776 https://reactome.org/PathwayBrowser/#/R-HSA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids TAS Homo sapiens 32551 R-HSA-375790 https://reactome.org/PathwayBrowser/#/R-HSA-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids TAS Homo sapiens 32551 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 32551 R-HSA-379432 https://reactome.org/PathwayBrowser/#/R-HSA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 32551 R-HSA-380008 https://reactome.org/PathwayBrowser/#/R-HSA-380008 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 32551 R-HSA-380233 https://reactome.org/PathwayBrowser/#/R-HSA-380233 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 32551 R-HSA-4167509 https://reactome.org/PathwayBrowser/#/R-HSA-4167509 Mitochondrial BTD hydrolyses BCTN TAS Homo sapiens 32551 R-HSA-420739 https://reactome.org/PathwayBrowser/#/R-HSA-420739 GPRC6A can bind L-alpha amino acids and calcium TAS Homo sapiens 32551 R-HSA-5655702 https://reactome.org/PathwayBrowser/#/R-HSA-5655702 Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 32551 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 32551 R-HSA-5660890 https://reactome.org/PathwayBrowser/#/R-HSA-5660890 Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 32551 R-HSA-5690319 https://reactome.org/PathwayBrowser/#/R-HSA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts TAS Homo sapiens 32551 R-HSA-70938 https://reactome.org/PathwayBrowser/#/R-HSA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O TAS Homo sapiens 32551 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 32551 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 32551 R-HSA-8932851 https://reactome.org/PathwayBrowser/#/R-HSA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol TAS Homo sapiens 32551 R-HSA-8959781 https://reactome.org/PathwayBrowser/#/R-HSA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix TAS Homo sapiens 32551 R-HSA-9023159 https://reactome.org/PathwayBrowser/#/R-HSA-9023159 Carboxypeptidase E hydrolyzes Insulin(57-89) to yield C-peptide (Insulin(57-87)) IEA Homo sapiens 32551 R-MMU-3076905 https://reactome.org/PathwayBrowser/#/R-MMU-3076905 Extracellular BTD hydrolyses BCTN IEA Mus musculus 32551 R-MMU-352136 https://reactome.org/PathwayBrowser/#/R-MMU-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Mus musculus 32551 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 32551 R-MMU-375770 https://reactome.org/PathwayBrowser/#/R-MMU-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Mus musculus 32551 R-MMU-375776 https://reactome.org/PathwayBrowser/#/R-MMU-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Mus musculus 32551 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 32551 R-MMU-379432 https://reactome.org/PathwayBrowser/#/R-MMU-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Mus musculus 32551 R-MMU-4167509 https://reactome.org/PathwayBrowser/#/R-MMU-4167509 Mitochondrial BTD hydrolyses BCTN IEA Mus musculus 32551 R-MMU-420739 https://reactome.org/PathwayBrowser/#/R-MMU-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Mus musculus 32551 R-MMU-5690319 https://reactome.org/PathwayBrowser/#/R-MMU-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Mus musculus 32551 R-MMU-70938 https://reactome.org/PathwayBrowser/#/R-MMU-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Mus musculus 32551 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 32551 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 32551 R-MMU-8932851 https://reactome.org/PathwayBrowser/#/R-MMU-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Mus musculus 32551 R-MMU-8959781 https://reactome.org/PathwayBrowser/#/R-MMU-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Mus musculus 32551 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 32551 R-PFA-5690319 https://reactome.org/PathwayBrowser/#/R-PFA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Plasmodium falciparum 32551 R-RNO-3076905 https://reactome.org/PathwayBrowser/#/R-RNO-3076905 Extracellular BTD hydrolyses BCTN IEA Rattus norvegicus 32551 R-RNO-352136 https://reactome.org/PathwayBrowser/#/R-RNO-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Rattus norvegicus 32551 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 32551 R-RNO-375770 https://reactome.org/PathwayBrowser/#/R-RNO-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Rattus norvegicus 32551 R-RNO-375776 https://reactome.org/PathwayBrowser/#/R-RNO-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Rattus norvegicus 32551 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 32551 R-RNO-379432 https://reactome.org/PathwayBrowser/#/R-RNO-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Rattus norvegicus 32551 R-RNO-4167509 https://reactome.org/PathwayBrowser/#/R-RNO-4167509 Mitochondrial BTD hydrolyses BCTN IEA Rattus norvegicus 32551 R-RNO-420739 https://reactome.org/PathwayBrowser/#/R-RNO-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Rattus norvegicus 32551 R-RNO-5690319 https://reactome.org/PathwayBrowser/#/R-RNO-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Rattus norvegicus 32551 R-RNO-70938 https://reactome.org/PathwayBrowser/#/R-RNO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Rattus norvegicus 32551 R-RNO-8932851 https://reactome.org/PathwayBrowser/#/R-RNO-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Rattus norvegicus 32551 R-RNO-8959781 https://reactome.org/PathwayBrowser/#/R-RNO-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Rattus norvegicus 32551 R-SCE-352136 https://reactome.org/PathwayBrowser/#/R-SCE-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Saccharomyces cerevisiae 32551 R-SCE-379432 https://reactome.org/PathwayBrowser/#/R-SCE-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Saccharomyces cerevisiae 32551 R-SCE-5690319 https://reactome.org/PathwayBrowser/#/R-SCE-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Saccharomyces cerevisiae 32551 R-SCE-70938 https://reactome.org/PathwayBrowser/#/R-SCE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Saccharomyces cerevisiae 32551 R-SCE-8932851 https://reactome.org/PathwayBrowser/#/R-SCE-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Saccharomyces cerevisiae 32551 R-SPO-5690319 https://reactome.org/PathwayBrowser/#/R-SPO-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Schizosaccharomyces pombe 32551 R-SPO-70938 https://reactome.org/PathwayBrowser/#/R-SPO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Schizosaccharomyces pombe 32551 R-SPO-8932851 https://reactome.org/PathwayBrowser/#/R-SPO-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Schizosaccharomyces pombe 32551 R-SSC-3076905 https://reactome.org/PathwayBrowser/#/R-SSC-3076905 Extracellular BTD hydrolyses BCTN IEA Sus scrofa 32551 R-SSC-352136 https://reactome.org/PathwayBrowser/#/R-SSC-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Sus scrofa 32551 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 32551 R-SSC-375768 https://reactome.org/PathwayBrowser/#/R-SSC-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Sus scrofa 32551 R-SSC-375770 https://reactome.org/PathwayBrowser/#/R-SSC-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Sus scrofa 32551 R-SSC-375776 https://reactome.org/PathwayBrowser/#/R-SSC-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Sus scrofa 32551 R-SSC-375790 https://reactome.org/PathwayBrowser/#/R-SSC-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Sus scrofa 32551 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 32551 R-SSC-379432 https://reactome.org/PathwayBrowser/#/R-SSC-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Sus scrofa 32551 R-SSC-4167509 https://reactome.org/PathwayBrowser/#/R-SSC-4167509 Mitochondrial BTD hydrolyses BCTN IEA Sus scrofa 32551 R-SSC-420739 https://reactome.org/PathwayBrowser/#/R-SSC-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Sus scrofa 32551 R-SSC-5690319 https://reactome.org/PathwayBrowser/#/R-SSC-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Sus scrofa 32551 R-SSC-70938 https://reactome.org/PathwayBrowser/#/R-SSC-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Sus scrofa 32551 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 32551 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 32551 R-SSC-8932851 https://reactome.org/PathwayBrowser/#/R-SSC-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Sus scrofa 32551 R-XTR-3076905 https://reactome.org/PathwayBrowser/#/R-XTR-3076905 Extracellular BTD hydrolyses BCTN IEA Xenopus tropicalis 32551 R-XTR-352136 https://reactome.org/PathwayBrowser/#/R-XTR-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Xenopus tropicalis 32551 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 32551 R-XTR-375768 https://reactome.org/PathwayBrowser/#/R-XTR-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 32551 R-XTR-375770 https://reactome.org/PathwayBrowser/#/R-XTR-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 32551 R-XTR-375776 https://reactome.org/PathwayBrowser/#/R-XTR-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 32551 R-XTR-375790 https://reactome.org/PathwayBrowser/#/R-XTR-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 32551 R-XTR-379432 https://reactome.org/PathwayBrowser/#/R-XTR-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Xenopus tropicalis 32551 R-XTR-4167509 https://reactome.org/PathwayBrowser/#/R-XTR-4167509 Mitochondrial BTD hydrolyses BCTN IEA Xenopus tropicalis 32551 R-XTR-420739 https://reactome.org/PathwayBrowser/#/R-XTR-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Xenopus tropicalis 32551 R-XTR-5690319 https://reactome.org/PathwayBrowser/#/R-XTR-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Xenopus tropicalis 32551 R-XTR-70938 https://reactome.org/PathwayBrowser/#/R-XTR-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Xenopus tropicalis 32551 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 32551 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 32551 R-XTR-8932851 https://reactome.org/PathwayBrowser/#/R-XTR-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Xenopus tropicalis 32551 R-XTR-8959781 https://reactome.org/PathwayBrowser/#/R-XTR-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Xenopus tropicalis 32587 R-BTA-159567 https://reactome.org/PathwayBrowser/#/R-BTA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Bos taurus 32587 R-BTA-159574 https://reactome.org/PathwayBrowser/#/R-BTA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Bos taurus 32587 R-CEL-159574 https://reactome.org/PathwayBrowser/#/R-CEL-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Caenorhabditis elegans 32587 R-CFA-159567 https://reactome.org/PathwayBrowser/#/R-CFA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Canis familiaris 32587 R-CFA-159574 https://reactome.org/PathwayBrowser/#/R-CFA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Canis familiaris 32587 R-DRE-159567 https://reactome.org/PathwayBrowser/#/R-DRE-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Danio rerio 32587 R-GGA-159567 https://reactome.org/PathwayBrowser/#/R-GGA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Gallus gallus 32587 R-GGA-159574 https://reactome.org/PathwayBrowser/#/R-GGA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Gallus gallus 32587 R-HSA-159567 https://reactome.org/PathwayBrowser/#/R-HSA-159567 ACSM2B-like proteins transform ST to ST-CoA TAS Homo sapiens 32587 R-HSA-159574 https://reactome.org/PathwayBrowser/#/R-HSA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA TAS Homo sapiens 32587 R-MMU-159567 https://reactome.org/PathwayBrowser/#/R-MMU-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Mus musculus 32587 R-MMU-159574 https://reactome.org/PathwayBrowser/#/R-MMU-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Mus musculus 32587 R-RNO-159567 https://reactome.org/PathwayBrowser/#/R-RNO-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Rattus norvegicus 32587 R-RNO-159574 https://reactome.org/PathwayBrowser/#/R-RNO-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Rattus norvegicus 32587 R-SSC-159567 https://reactome.org/PathwayBrowser/#/R-SSC-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Sus scrofa 32587 R-SSC-159574 https://reactome.org/PathwayBrowser/#/R-SSC-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Sus scrofa 32587 R-XTR-159567 https://reactome.org/PathwayBrowser/#/R-XTR-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Xenopus tropicalis 32587 R-XTR-159574 https://reactome.org/PathwayBrowser/#/R-XTR-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Xenopus tropicalis 326268 R-BTA-141348 https://reactome.org/PathwayBrowser/#/R-BTA-141348 PAO:FAD oxidises NASPM to PTCN IEA Bos taurus 326268 R-BTA-350604 https://reactome.org/PathwayBrowser/#/R-BTA-350604 Agmatine + H2O <=> putrescine + urea IEA Bos taurus 326268 R-BTA-351215 https://reactome.org/PathwayBrowser/#/R-BTA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Bos taurus 326268 R-BTA-70692 https://reactome.org/PathwayBrowser/#/R-BTA-70692 ornithine => putrescine + CO2 IEA Bos taurus 326268 R-CEL-141348 https://reactome.org/PathwayBrowser/#/R-CEL-141348 PAO:FAD oxidises NASPM to PTCN IEA Caenorhabditis elegans 326268 R-CEL-351215 https://reactome.org/PathwayBrowser/#/R-CEL-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Caenorhabditis elegans 326268 R-CEL-70692 https://reactome.org/PathwayBrowser/#/R-CEL-70692 ornithine => putrescine + CO2 IEA Caenorhabditis elegans 326268 R-CFA-141348 https://reactome.org/PathwayBrowser/#/R-CFA-141348 PAO:FAD oxidises NASPM to PTCN IEA Canis familiaris 326268 R-CFA-350604 https://reactome.org/PathwayBrowser/#/R-CFA-350604 Agmatine + H2O <=> putrescine + urea IEA Canis familiaris 326268 R-CFA-351215 https://reactome.org/PathwayBrowser/#/R-CFA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Canis familiaris 326268 R-CFA-70692 https://reactome.org/PathwayBrowser/#/R-CFA-70692 ornithine => putrescine + CO2 IEA Canis familiaris 326268 R-DDI-351215 https://reactome.org/PathwayBrowser/#/R-DDI-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Dictyostelium discoideum 326268 R-DDI-70692 https://reactome.org/PathwayBrowser/#/R-DDI-70692 ornithine => putrescine + CO2 IEA Dictyostelium discoideum 326268 R-DME-141348 https://reactome.org/PathwayBrowser/#/R-DME-141348 PAO:FAD oxidises NASPM to PTCN IEA Drosophila melanogaster 326268 R-DME-351215 https://reactome.org/PathwayBrowser/#/R-DME-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Drosophila melanogaster 326268 R-DME-70692 https://reactome.org/PathwayBrowser/#/R-DME-70692 ornithine => putrescine + CO2 IEA Drosophila melanogaster 326268 R-DRE-141348 https://reactome.org/PathwayBrowser/#/R-DRE-141348 PAO:FAD oxidises NASPM to PTCN IEA Danio rerio 326268 R-DRE-350604 https://reactome.org/PathwayBrowser/#/R-DRE-350604 Agmatine + H2O <=> putrescine + urea IEA Danio rerio 326268 R-DRE-70692 https://reactome.org/PathwayBrowser/#/R-DRE-70692 ornithine => putrescine + CO2 IEA Danio rerio 326268 R-GGA-141348 https://reactome.org/PathwayBrowser/#/R-GGA-141348 PAO:FAD oxidises NASPM to PTCN IEA Gallus gallus 326268 R-GGA-350604 https://reactome.org/PathwayBrowser/#/R-GGA-350604 Agmatine + H2O <=> putrescine + urea IEA Gallus gallus 326268 R-GGA-351215 https://reactome.org/PathwayBrowser/#/R-GGA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Gallus gallus 326268 R-GGA-70692 https://reactome.org/PathwayBrowser/#/R-GGA-70692 ornithine => putrescine + CO2 IEA Gallus gallus 326268 R-HSA-141348 https://reactome.org/PathwayBrowser/#/R-HSA-141348 PAO:FAD oxidises NASPM to PTCN TAS Homo sapiens 326268 R-HSA-350604 https://reactome.org/PathwayBrowser/#/R-HSA-350604 Agmatine + H2O <=> putrescine + urea TAS Homo sapiens 326268 R-HSA-351215 https://reactome.org/PathwayBrowser/#/R-HSA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine TAS Homo sapiens 326268 R-HSA-70692 https://reactome.org/PathwayBrowser/#/R-HSA-70692 ornithine => putrescine + CO2 TAS Homo sapiens 326268 R-MMU-141348 https://reactome.org/PathwayBrowser/#/R-MMU-141348 PAO:FAD oxidises NASPM to PTCN IEA Mus musculus 326268 R-MMU-350604 https://reactome.org/PathwayBrowser/#/R-MMU-350604 Agmatine + H2O <=> putrescine + urea IEA Mus musculus 326268 R-MMU-351215 https://reactome.org/PathwayBrowser/#/R-MMU-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Mus musculus 326268 R-MMU-70692 https://reactome.org/PathwayBrowser/#/R-MMU-70692 ornithine => putrescine + CO2 IEA Mus musculus 326268 R-PFA-351215 https://reactome.org/PathwayBrowser/#/R-PFA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Plasmodium falciparum 326268 R-PFA-70692 https://reactome.org/PathwayBrowser/#/R-PFA-70692 ornithine => putrescine + CO2 IEA Plasmodium falciparum 326268 R-RNO-141348 https://reactome.org/PathwayBrowser/#/R-RNO-141348 PAO:FAD oxidises NASPM to PTCN IEA Rattus norvegicus 326268 R-RNO-350604 https://reactome.org/PathwayBrowser/#/R-RNO-350604 Agmatine + H2O <=> putrescine + urea IEA Rattus norvegicus 326268 R-RNO-351215 https://reactome.org/PathwayBrowser/#/R-RNO-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Rattus norvegicus 326268 R-RNO-70692 https://reactome.org/PathwayBrowser/#/R-RNO-70692 ornithine => putrescine + CO2 IEA Rattus norvegicus 326268 R-SCE-351215 https://reactome.org/PathwayBrowser/#/R-SCE-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Saccharomyces cerevisiae 326268 R-SCE-70692 https://reactome.org/PathwayBrowser/#/R-SCE-70692 ornithine => putrescine + CO2 IEA Saccharomyces cerevisiae 326268 R-SPO-351215 https://reactome.org/PathwayBrowser/#/R-SPO-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Schizosaccharomyces pombe 326268 R-SPO-70692 https://reactome.org/PathwayBrowser/#/R-SPO-70692 ornithine => putrescine + CO2 IEA Schizosaccharomyces pombe 326268 R-SSC-141348 https://reactome.org/PathwayBrowser/#/R-SSC-141348 PAO:FAD oxidises NASPM to PTCN IEA Sus scrofa 326268 R-SSC-350604 https://reactome.org/PathwayBrowser/#/R-SSC-350604 Agmatine + H2O <=> putrescine + urea IEA Sus scrofa 326268 R-SSC-351215 https://reactome.org/PathwayBrowser/#/R-SSC-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Sus scrofa 326268 R-SSC-70692 https://reactome.org/PathwayBrowser/#/R-SSC-70692 ornithine => putrescine + CO2 IEA Sus scrofa 326268 R-XTR-350604 https://reactome.org/PathwayBrowser/#/R-XTR-350604 Agmatine + H2O <=> putrescine + urea IEA Xenopus tropicalis 326268 R-XTR-351215 https://reactome.org/PathwayBrowser/#/R-XTR-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Xenopus tropicalis 326268 R-XTR-70692 https://reactome.org/PathwayBrowser/#/R-XTR-70692 ornithine => putrescine + CO2 IEA Xenopus tropicalis 32635 R-BTA-158468 https://reactome.org/PathwayBrowser/#/R-BTA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Bos taurus 32635 R-BTA-9753277 https://reactome.org/PathwayBrowser/#/R-BTA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Bos taurus 32635 R-BTA-9753278 https://reactome.org/PathwayBrowser/#/R-BTA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 32635 R-BTA-9753283 https://reactome.org/PathwayBrowser/#/R-BTA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 32635 R-CEL-9753278 https://reactome.org/PathwayBrowser/#/R-CEL-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 32635 R-CEL-9753283 https://reactome.org/PathwayBrowser/#/R-CEL-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 32635 R-CFA-158468 https://reactome.org/PathwayBrowser/#/R-CFA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Canis familiaris 32635 R-CFA-9753277 https://reactome.org/PathwayBrowser/#/R-CFA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Canis familiaris 32635 R-CFA-9753278 https://reactome.org/PathwayBrowser/#/R-CFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 32635 R-CFA-9753283 https://reactome.org/PathwayBrowser/#/R-CFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 32635 R-DDI-9753278 https://reactome.org/PathwayBrowser/#/R-DDI-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 32635 R-DDI-9753283 https://reactome.org/PathwayBrowser/#/R-DDI-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 32635 R-DME-158468 https://reactome.org/PathwayBrowser/#/R-DME-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Drosophila melanogaster 32635 R-DME-9753277 https://reactome.org/PathwayBrowser/#/R-DME-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Drosophila melanogaster 32635 R-DME-9753278 https://reactome.org/PathwayBrowser/#/R-DME-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 32635 R-DME-9753283 https://reactome.org/PathwayBrowser/#/R-DME-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 32635 R-DRE-158468 https://reactome.org/PathwayBrowser/#/R-DRE-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Danio rerio 32635 R-DRE-9753277 https://reactome.org/PathwayBrowser/#/R-DRE-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Danio rerio 32635 R-DRE-9753278 https://reactome.org/PathwayBrowser/#/R-DRE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 32635 R-DRE-9753283 https://reactome.org/PathwayBrowser/#/R-DRE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 32635 R-GGA-158468 https://reactome.org/PathwayBrowser/#/R-GGA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Gallus gallus 32635 R-GGA-9753277 https://reactome.org/PathwayBrowser/#/R-GGA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Gallus gallus 32635 R-GGA-9753278 https://reactome.org/PathwayBrowser/#/R-GGA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 32635 R-GGA-9753283 https://reactome.org/PathwayBrowser/#/R-GGA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 32635 R-HSA-158468 https://reactome.org/PathwayBrowser/#/R-HSA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 TAS Homo sapiens 32635 R-HSA-9753277 https://reactome.org/PathwayBrowser/#/R-HSA-9753277 SULT dimers sulfate APAP to APAP-SO3 TAS Homo sapiens 32635 R-HSA-9753278 https://reactome.org/PathwayBrowser/#/R-HSA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 32635 R-HSA-9753283 https://reactome.org/PathwayBrowser/#/R-HSA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 32635 R-MMU-158468 https://reactome.org/PathwayBrowser/#/R-MMU-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Mus musculus 32635 R-MMU-9753277 https://reactome.org/PathwayBrowser/#/R-MMU-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Mus musculus 32635 R-MMU-9753278 https://reactome.org/PathwayBrowser/#/R-MMU-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 32635 R-MMU-9753283 https://reactome.org/PathwayBrowser/#/R-MMU-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 32635 R-PFA-9753278 https://reactome.org/PathwayBrowser/#/R-PFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 32635 R-PFA-9753283 https://reactome.org/PathwayBrowser/#/R-PFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 32635 R-RNO-158468 https://reactome.org/PathwayBrowser/#/R-RNO-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Rattus norvegicus 32635 R-RNO-9753277 https://reactome.org/PathwayBrowser/#/R-RNO-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Rattus norvegicus 32635 R-RNO-9753278 https://reactome.org/PathwayBrowser/#/R-RNO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 32635 R-RNO-9753283 https://reactome.org/PathwayBrowser/#/R-RNO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 32635 R-SCE-9753278 https://reactome.org/PathwayBrowser/#/R-SCE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 32635 R-SCE-9753283 https://reactome.org/PathwayBrowser/#/R-SCE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 32635 R-SPO-9753278 https://reactome.org/PathwayBrowser/#/R-SPO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 32635 R-SPO-9753283 https://reactome.org/PathwayBrowser/#/R-SPO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 32635 R-SSC-158468 https://reactome.org/PathwayBrowser/#/R-SSC-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Sus scrofa 32635 R-SSC-9753277 https://reactome.org/PathwayBrowser/#/R-SSC-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Sus scrofa 32635 R-SSC-9753278 https://reactome.org/PathwayBrowser/#/R-SSC-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 32635 R-SSC-9753283 https://reactome.org/PathwayBrowser/#/R-SSC-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 32635 R-XTR-158468 https://reactome.org/PathwayBrowser/#/R-XTR-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Xenopus tropicalis 32635 R-XTR-9753277 https://reactome.org/PathwayBrowser/#/R-XTR-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Xenopus tropicalis 32635 R-XTR-9753278 https://reactome.org/PathwayBrowser/#/R-XTR-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 32635 R-XTR-9753283 https://reactome.org/PathwayBrowser/#/R-XTR-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 32636 R-BTA-9753278 https://reactome.org/PathwayBrowser/#/R-BTA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 32636 R-BTA-9753283 https://reactome.org/PathwayBrowser/#/R-BTA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 32636 R-CEL-9753278 https://reactome.org/PathwayBrowser/#/R-CEL-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 32636 R-CEL-9753283 https://reactome.org/PathwayBrowser/#/R-CEL-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 32636 R-CFA-9753278 https://reactome.org/PathwayBrowser/#/R-CFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 32636 R-CFA-9753283 https://reactome.org/PathwayBrowser/#/R-CFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 32636 R-DDI-9753278 https://reactome.org/PathwayBrowser/#/R-DDI-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 32636 R-DDI-9753283 https://reactome.org/PathwayBrowser/#/R-DDI-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 32636 R-DME-9753278 https://reactome.org/PathwayBrowser/#/R-DME-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 32636 R-DME-9753283 https://reactome.org/PathwayBrowser/#/R-DME-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 32636 R-DRE-9753278 https://reactome.org/PathwayBrowser/#/R-DRE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 32636 R-DRE-9753283 https://reactome.org/PathwayBrowser/#/R-DRE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 32636 R-GGA-9753278 https://reactome.org/PathwayBrowser/#/R-GGA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 32636 R-GGA-9753283 https://reactome.org/PathwayBrowser/#/R-GGA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 32636 R-HSA-9753278 https://reactome.org/PathwayBrowser/#/R-HSA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 32636 R-HSA-9753283 https://reactome.org/PathwayBrowser/#/R-HSA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 32636 R-MMU-9753278 https://reactome.org/PathwayBrowser/#/R-MMU-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 32636 R-MMU-9753283 https://reactome.org/PathwayBrowser/#/R-MMU-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 32636 R-PFA-9753278 https://reactome.org/PathwayBrowser/#/R-PFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 32636 R-PFA-9753283 https://reactome.org/PathwayBrowser/#/R-PFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 32636 R-RNO-9753278 https://reactome.org/PathwayBrowser/#/R-RNO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 32636 R-RNO-9753283 https://reactome.org/PathwayBrowser/#/R-RNO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 32636 R-SCE-9753278 https://reactome.org/PathwayBrowser/#/R-SCE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 32636 R-SCE-9753283 https://reactome.org/PathwayBrowser/#/R-SCE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 32636 R-SPO-9753278 https://reactome.org/PathwayBrowser/#/R-SPO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 32636 R-SPO-9753283 https://reactome.org/PathwayBrowser/#/R-SPO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 32636 R-SSC-9753278 https://reactome.org/PathwayBrowser/#/R-SSC-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 32636 R-SSC-9753283 https://reactome.org/PathwayBrowser/#/R-SSC-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 32636 R-XTR-9753278 https://reactome.org/PathwayBrowser/#/R-XTR-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 32636 R-XTR-9753283 https://reactome.org/PathwayBrowser/#/R-XTR-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 32639 R-BTA-176054 https://reactome.org/PathwayBrowser/#/R-BTA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Bos taurus 32639 R-BTA-176059 https://reactome.org/PathwayBrowser/#/R-BTA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Bos taurus 32639 R-BTA-9753280 https://reactome.org/PathwayBrowser/#/R-BTA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Bos taurus 32639 R-BTA-9753634 https://reactome.org/PathwayBrowser/#/R-BTA-9753634 GGT dimers hydrolyse APAP-SG IEA Bos taurus 32639 R-CEL-176054 https://reactome.org/PathwayBrowser/#/R-CEL-176054 GST dimers conjugate GSH with cytosolic substrates IEA Caenorhabditis elegans 32639 R-CEL-9753280 https://reactome.org/PathwayBrowser/#/R-CEL-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Caenorhabditis elegans 32639 R-CEL-9753634 https://reactome.org/PathwayBrowser/#/R-CEL-9753634 GGT dimers hydrolyse APAP-SG IEA Caenorhabditis elegans 32639 R-CFA-176054 https://reactome.org/PathwayBrowser/#/R-CFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Canis familiaris 32639 R-CFA-176059 https://reactome.org/PathwayBrowser/#/R-CFA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Canis familiaris 32639 R-CFA-9753280 https://reactome.org/PathwayBrowser/#/R-CFA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Canis familiaris 32639 R-CFA-9753634 https://reactome.org/PathwayBrowser/#/R-CFA-9753634 GGT dimers hydrolyse APAP-SG IEA Canis familiaris 32639 R-DDI-176054 https://reactome.org/PathwayBrowser/#/R-DDI-176054 GST dimers conjugate GSH with cytosolic substrates IEA Dictyostelium discoideum 32639 R-DDI-176059 https://reactome.org/PathwayBrowser/#/R-DDI-176059 GST trimers transfer GS from GSH to luminal substrates IEA Dictyostelium discoideum 32639 R-DDI-9753280 https://reactome.org/PathwayBrowser/#/R-DDI-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Dictyostelium discoideum 32639 R-DME-176054 https://reactome.org/PathwayBrowser/#/R-DME-176054 GST dimers conjugate GSH with cytosolic substrates IEA Drosophila melanogaster 32639 R-DME-176059 https://reactome.org/PathwayBrowser/#/R-DME-176059 GST trimers transfer GS from GSH to luminal substrates IEA Drosophila melanogaster 32639 R-DME-9753280 https://reactome.org/PathwayBrowser/#/R-DME-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Drosophila melanogaster 32639 R-DME-9753634 https://reactome.org/PathwayBrowser/#/R-DME-9753634 GGT dimers hydrolyse APAP-SG IEA Drosophila melanogaster 32639 R-DRE-176054 https://reactome.org/PathwayBrowser/#/R-DRE-176054 GST dimers conjugate GSH with cytosolic substrates IEA Danio rerio 32639 R-DRE-176059 https://reactome.org/PathwayBrowser/#/R-DRE-176059 GST trimers transfer GS from GSH to luminal substrates IEA Danio rerio 32639 R-DRE-9753280 https://reactome.org/PathwayBrowser/#/R-DRE-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Danio rerio 32639 R-GGA-176054 https://reactome.org/PathwayBrowser/#/R-GGA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Gallus gallus 32639 R-GGA-176059 https://reactome.org/PathwayBrowser/#/R-GGA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Gallus gallus 32639 R-GGA-9753280 https://reactome.org/PathwayBrowser/#/R-GGA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Gallus gallus 32639 R-GGA-9753634 https://reactome.org/PathwayBrowser/#/R-GGA-9753634 GGT dimers hydrolyse APAP-SG IEA Gallus gallus 32639 R-HSA-176054 https://reactome.org/PathwayBrowser/#/R-HSA-176054 GST dimers conjugate GSH with cytosolic substrates TAS Homo sapiens 32639 R-HSA-176059 https://reactome.org/PathwayBrowser/#/R-HSA-176059 GST trimers transfer GS from GSH to luminal substrates TAS Homo sapiens 32639 R-HSA-9753280 https://reactome.org/PathwayBrowser/#/R-HSA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG TAS Homo sapiens 32639 R-HSA-9753634 https://reactome.org/PathwayBrowser/#/R-HSA-9753634 GGT dimers hydrolyse APAP-SG TAS Homo sapiens 32639 R-MMU-176054 https://reactome.org/PathwayBrowser/#/R-MMU-176054 GST dimers conjugate GSH with cytosolic substrates IEA Mus musculus 32639 R-MMU-176059 https://reactome.org/PathwayBrowser/#/R-MMU-176059 GST trimers transfer GS from GSH to luminal substrates IEA Mus musculus 32639 R-MMU-9753280 https://reactome.org/PathwayBrowser/#/R-MMU-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Mus musculus 32639 R-MMU-9753634 https://reactome.org/PathwayBrowser/#/R-MMU-9753634 GGT dimers hydrolyse APAP-SG IEA Mus musculus 32639 R-PFA-176054 https://reactome.org/PathwayBrowser/#/R-PFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Plasmodium falciparum 32639 R-PFA-9753280 https://reactome.org/PathwayBrowser/#/R-PFA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Plasmodium falciparum 32639 R-RNO-176054 https://reactome.org/PathwayBrowser/#/R-RNO-176054 GST dimers conjugate GSH with cytosolic substrates IEA Rattus norvegicus 32639 R-RNO-176059 https://reactome.org/PathwayBrowser/#/R-RNO-176059 GST trimers transfer GS from GSH to luminal substrates IEA Rattus norvegicus 32639 R-RNO-9753280 https://reactome.org/PathwayBrowser/#/R-RNO-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Rattus norvegicus 32639 R-RNO-9753634 https://reactome.org/PathwayBrowser/#/R-RNO-9753634 GGT dimers hydrolyse APAP-SG IEA Rattus norvegicus 32639 R-SCE-9753634 https://reactome.org/PathwayBrowser/#/R-SCE-9753634 GGT dimers hydrolyse APAP-SG IEA Saccharomyces cerevisiae 32639 R-SPO-9753634 https://reactome.org/PathwayBrowser/#/R-SPO-9753634 GGT dimers hydrolyse APAP-SG IEA Schizosaccharomyces pombe 32639 R-SSC-176054 https://reactome.org/PathwayBrowser/#/R-SSC-176054 GST dimers conjugate GSH with cytosolic substrates IEA Sus scrofa 32639 R-SSC-176059 https://reactome.org/PathwayBrowser/#/R-SSC-176059 GST trimers transfer GS from GSH to luminal substrates IEA Sus scrofa 32639 R-SSC-9753280 https://reactome.org/PathwayBrowser/#/R-SSC-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Sus scrofa 32639 R-SSC-9753634 https://reactome.org/PathwayBrowser/#/R-SSC-9753634 GGT dimers hydrolyse APAP-SG IEA Sus scrofa 32639 R-XTR-176054 https://reactome.org/PathwayBrowser/#/R-XTR-176054 GST dimers conjugate GSH with cytosolic substrates IEA Xenopus tropicalis 32639 R-XTR-176059 https://reactome.org/PathwayBrowser/#/R-XTR-176059 GST trimers transfer GS from GSH to luminal substrates IEA Xenopus tropicalis 32639 R-XTR-9753280 https://reactome.org/PathwayBrowser/#/R-XTR-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Xenopus tropicalis 32643 R-BTA-174967 https://reactome.org/PathwayBrowser/#/R-BTA-174967 NAT2 acetylation IEA Bos taurus 32643 R-DRE-174967 https://reactome.org/PathwayBrowser/#/R-DRE-174967 NAT2 acetylation IEA Danio rerio 32643 R-GGA-174967 https://reactome.org/PathwayBrowser/#/R-GGA-174967 NAT2 acetylation IEA Gallus gallus 32643 R-HSA-174967 https://reactome.org/PathwayBrowser/#/R-HSA-174967 NAT2 acetylation TAS Homo sapiens 32643 R-MMU-174967 https://reactome.org/PathwayBrowser/#/R-MMU-174967 NAT2 acetylation IEA Mus musculus 32643 R-RNO-174967 https://reactome.org/PathwayBrowser/#/R-RNO-174967 NAT2 acetylation IEA Rattus norvegicus 32643 R-SSC-174967 https://reactome.org/PathwayBrowser/#/R-SSC-174967 NAT2 acetylation IEA Sus scrofa 32649 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 32649 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 32649 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 32649 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 32649 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 32663 R-BTA-174916 https://reactome.org/PathwayBrowser/#/R-BTA-174916 Formation of N-glucuronides IEA Bos taurus 32663 R-DDI-174916 https://reactome.org/PathwayBrowser/#/R-DDI-174916 Formation of N-glucuronides IEA Dictyostelium discoideum 32663 R-GGA-174916 https://reactome.org/PathwayBrowser/#/R-GGA-174916 Formation of N-glucuronides IEA Gallus gallus 32663 R-HSA-174916 https://reactome.org/PathwayBrowser/#/R-HSA-174916 Formation of N-glucuronides TAS Homo sapiens 32663 R-MMU-174916 https://reactome.org/PathwayBrowser/#/R-MMU-174916 Formation of N-glucuronides IEA Mus musculus 32663 R-RNO-174916 https://reactome.org/PathwayBrowser/#/R-RNO-174916 Formation of N-glucuronides IEA Rattus norvegicus 32663 R-SSC-174916 https://reactome.org/PathwayBrowser/#/R-SSC-174916 Formation of N-glucuronides IEA Sus scrofa 32682 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 32682 R-BTA-350598 https://reactome.org/PathwayBrowser/#/R-BTA-350598 Arginine<=>Agmatine+CO2 IEA Bos taurus 32682 R-BTA-352136 https://reactome.org/PathwayBrowser/#/R-BTA-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Bos taurus 32682 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 32682 R-BTA-375770 https://reactome.org/PathwayBrowser/#/R-BTA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Bos taurus 32682 R-BTA-375776 https://reactome.org/PathwayBrowser/#/R-BTA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Bos taurus 32682 R-BTA-379415 https://reactome.org/PathwayBrowser/#/R-BTA-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Bos taurus 32682 R-BTA-379426 https://reactome.org/PathwayBrowser/#/R-BTA-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Bos taurus 32682 R-BTA-379432 https://reactome.org/PathwayBrowser/#/R-BTA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Bos taurus 32682 R-BTA-418436 https://reactome.org/PathwayBrowser/#/R-BTA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Bos taurus 32682 R-BTA-452036 https://reactome.org/PathwayBrowser/#/R-BTA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Bos taurus 32682 R-BTA-70542 https://reactome.org/PathwayBrowser/#/R-BTA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Bos taurus 32682 R-BTA-70569 https://reactome.org/PathwayBrowser/#/R-BTA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Bos taurus 32682 R-BTA-70573 https://reactome.org/PathwayBrowser/#/R-BTA-70573 argininosuccinate <=> fumarate + arginine IEA Bos taurus 32682 R-BTA-71275 https://reactome.org/PathwayBrowser/#/R-BTA-71275 arginine + glycine => ornithine + guanidoacetate IEA Bos taurus 32682 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 32682 R-BTA-8932851 https://reactome.org/PathwayBrowser/#/R-BTA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Bos taurus 32682 R-BTA-8936442 https://reactome.org/PathwayBrowser/#/R-BTA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Bos taurus 32682 R-BTA-8952726 https://reactome.org/PathwayBrowser/#/R-BTA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Bos taurus 32682 R-BTA-8959781 https://reactome.org/PathwayBrowser/#/R-BTA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Bos taurus 32682 R-BTA-9640167 https://reactome.org/PathwayBrowser/#/R-BTA-9640167 RRAGA,B exchanges GDP for GTP IEA Bos taurus 32682 R-BTA-9640168 https://reactome.org/PathwayBrowser/#/R-BTA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Bos taurus 32682 R-BTA-9640175 https://reactome.org/PathwayBrowser/#/R-BTA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Bos taurus 32682 R-BTA-9640237 https://reactome.org/PathwayBrowser/#/R-BTA-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Bos taurus 32682 R-BTA-9657619 https://reactome.org/PathwayBrowser/#/R-BTA-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Bos taurus 32682 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 32682 R-CEL-350598 https://reactome.org/PathwayBrowser/#/R-CEL-350598 Arginine<=>Agmatine+CO2 IEA Caenorhabditis elegans 32682 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 32682 R-CEL-452036 https://reactome.org/PathwayBrowser/#/R-CEL-452036 arginine + H2O => ornithine + urea [ARG2] IEA Caenorhabditis elegans 32682 R-CEL-70569 https://reactome.org/PathwayBrowser/#/R-CEL-70569 arginine + H2O => ornithine + urea [ARG1] IEA Caenorhabditis elegans 32682 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 32682 R-CEL-8932851 https://reactome.org/PathwayBrowser/#/R-CEL-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Caenorhabditis elegans 32682 R-CEL-8936442 https://reactome.org/PathwayBrowser/#/R-CEL-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Caenorhabditis elegans 32682 R-CEL-8952726 https://reactome.org/PathwayBrowser/#/R-CEL-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Caenorhabditis elegans 32682 R-CEL-8959781 https://reactome.org/PathwayBrowser/#/R-CEL-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Caenorhabditis elegans 32682 R-CEL-9640167 https://reactome.org/PathwayBrowser/#/R-CEL-9640167 RRAGA,B exchanges GDP for GTP IEA Caenorhabditis elegans 32682 R-CEL-9640168 https://reactome.org/PathwayBrowser/#/R-CEL-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Caenorhabditis elegans 32682 R-CEL-9640175 https://reactome.org/PathwayBrowser/#/R-CEL-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Caenorhabditis elegans 32682 R-CFA-350598 https://reactome.org/PathwayBrowser/#/R-CFA-350598 Arginine<=>Agmatine+CO2 IEA Canis familiaris 32682 R-CFA-352136 https://reactome.org/PathwayBrowser/#/R-CFA-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Canis familiaris 32682 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 32682 R-CFA-375768 https://reactome.org/PathwayBrowser/#/R-CFA-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Canis familiaris 32682 R-CFA-375770 https://reactome.org/PathwayBrowser/#/R-CFA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Canis familiaris 32682 R-CFA-375776 https://reactome.org/PathwayBrowser/#/R-CFA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Canis familiaris 32682 R-CFA-375790 https://reactome.org/PathwayBrowser/#/R-CFA-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Canis familiaris 32682 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 32682 R-CFA-379426 https://reactome.org/PathwayBrowser/#/R-CFA-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Canis familiaris 32682 R-CFA-379432 https://reactome.org/PathwayBrowser/#/R-CFA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Canis familiaris 32682 R-CFA-418436 https://reactome.org/PathwayBrowser/#/R-CFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Canis familiaris 32682 R-CFA-420739 https://reactome.org/PathwayBrowser/#/R-CFA-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Canis familiaris 32682 R-CFA-452036 https://reactome.org/PathwayBrowser/#/R-CFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Canis familiaris 32682 R-CFA-70542 https://reactome.org/PathwayBrowser/#/R-CFA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Canis familiaris 32682 R-CFA-70569 https://reactome.org/PathwayBrowser/#/R-CFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Canis familiaris 32682 R-CFA-70573 https://reactome.org/PathwayBrowser/#/R-CFA-70573 argininosuccinate <=> fumarate + arginine IEA Canis familiaris 32682 R-CFA-71275 https://reactome.org/PathwayBrowser/#/R-CFA-71275 arginine + glycine => ornithine + guanidoacetate IEA Canis familiaris 32682 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 32682 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 32682 R-CFA-8932851 https://reactome.org/PathwayBrowser/#/R-CFA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Canis familiaris 32682 R-CFA-8936442 https://reactome.org/PathwayBrowser/#/R-CFA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Canis familiaris 32682 R-CFA-8952726 https://reactome.org/PathwayBrowser/#/R-CFA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Canis familiaris 32682 R-CFA-8959781 https://reactome.org/PathwayBrowser/#/R-CFA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Canis familiaris 32682 R-CFA-9640167 https://reactome.org/PathwayBrowser/#/R-CFA-9640167 RRAGA,B exchanges GDP for GTP IEA Canis familiaris 32682 R-CFA-9640168 https://reactome.org/PathwayBrowser/#/R-CFA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Canis familiaris 32682 R-CFA-9640175 https://reactome.org/PathwayBrowser/#/R-CFA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Canis familiaris 32682 R-CFA-9640237 https://reactome.org/PathwayBrowser/#/R-CFA-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Canis familiaris 32682 R-CFA-9657619 https://reactome.org/PathwayBrowser/#/R-CFA-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Canis familiaris 32682 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 32682 R-DDI-350598 https://reactome.org/PathwayBrowser/#/R-DDI-350598 Arginine<=>Agmatine+CO2 IEA Dictyostelium discoideum 32682 R-DDI-375768 https://reactome.org/PathwayBrowser/#/R-DDI-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 32682 R-DDI-375770 https://reactome.org/PathwayBrowser/#/R-DDI-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 32682 R-DDI-375776 https://reactome.org/PathwayBrowser/#/R-DDI-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 32682 R-DDI-375790 https://reactome.org/PathwayBrowser/#/R-DDI-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 32682 R-DDI-418436 https://reactome.org/PathwayBrowser/#/R-DDI-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Dictyostelium discoideum 32682 R-DDI-452036 https://reactome.org/PathwayBrowser/#/R-DDI-452036 arginine + H2O => ornithine + urea [ARG2] IEA Dictyostelium discoideum 32682 R-DDI-70542 https://reactome.org/PathwayBrowser/#/R-DDI-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Dictyostelium discoideum 32682 R-DDI-70569 https://reactome.org/PathwayBrowser/#/R-DDI-70569 arginine + H2O => ornithine + urea [ARG1] IEA Dictyostelium discoideum 32682 R-DDI-8936442 https://reactome.org/PathwayBrowser/#/R-DDI-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Dictyostelium discoideum 32682 R-DDI-8952726 https://reactome.org/PathwayBrowser/#/R-DDI-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Dictyostelium discoideum 32682 R-DDI-9640167 https://reactome.org/PathwayBrowser/#/R-DDI-9640167 RRAGA,B exchanges GDP for GTP IEA Dictyostelium discoideum 32682 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 32682 R-DME-350598 https://reactome.org/PathwayBrowser/#/R-DME-350598 Arginine<=>Agmatine+CO2 IEA Drosophila melanogaster 32682 R-DME-352136 https://reactome.org/PathwayBrowser/#/R-DME-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Drosophila melanogaster 32682 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 32682 R-DME-375768 https://reactome.org/PathwayBrowser/#/R-DME-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 32682 R-DME-375770 https://reactome.org/PathwayBrowser/#/R-DME-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 32682 R-DME-375776 https://reactome.org/PathwayBrowser/#/R-DME-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 32682 R-DME-375790 https://reactome.org/PathwayBrowser/#/R-DME-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 32682 R-DME-379415 https://reactome.org/PathwayBrowser/#/R-DME-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Drosophila melanogaster 32682 R-DME-379426 https://reactome.org/PathwayBrowser/#/R-DME-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Drosophila melanogaster 32682 R-DME-379432 https://reactome.org/PathwayBrowser/#/R-DME-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Drosophila melanogaster 32682 R-DME-418436 https://reactome.org/PathwayBrowser/#/R-DME-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Drosophila melanogaster 32682 R-DME-452036 https://reactome.org/PathwayBrowser/#/R-DME-452036 arginine + H2O => ornithine + urea [ARG2] IEA Drosophila melanogaster 32682 R-DME-70569 https://reactome.org/PathwayBrowser/#/R-DME-70569 arginine + H2O => ornithine + urea [ARG1] IEA Drosophila melanogaster 32682 R-DME-70573 https://reactome.org/PathwayBrowser/#/R-DME-70573 argininosuccinate <=> fumarate + arginine IEA Drosophila melanogaster 32682 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 32682 R-DME-8936442 https://reactome.org/PathwayBrowser/#/R-DME-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Drosophila melanogaster 32682 R-DME-8952726 https://reactome.org/PathwayBrowser/#/R-DME-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Drosophila melanogaster 32682 R-DME-8959781 https://reactome.org/PathwayBrowser/#/R-DME-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Drosophila melanogaster 32682 R-DME-9640167 https://reactome.org/PathwayBrowser/#/R-DME-9640167 RRAGA,B exchanges GDP for GTP IEA Drosophila melanogaster 32682 R-DRE-350598 https://reactome.org/PathwayBrowser/#/R-DRE-350598 Arginine<=>Agmatine+CO2 IEA Danio rerio 32682 R-DRE-375768 https://reactome.org/PathwayBrowser/#/R-DRE-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Danio rerio 32682 R-DRE-375776 https://reactome.org/PathwayBrowser/#/R-DRE-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Danio rerio 32682 R-DRE-375790 https://reactome.org/PathwayBrowser/#/R-DRE-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Danio rerio 32682 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 32682 R-DRE-379415 https://reactome.org/PathwayBrowser/#/R-DRE-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Danio rerio 32682 R-DRE-379426 https://reactome.org/PathwayBrowser/#/R-DRE-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Danio rerio 32682 R-DRE-418436 https://reactome.org/PathwayBrowser/#/R-DRE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Danio rerio 32682 R-DRE-420739 https://reactome.org/PathwayBrowser/#/R-DRE-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Danio rerio 32682 R-DRE-452036 https://reactome.org/PathwayBrowser/#/R-DRE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Danio rerio 32682 R-DRE-70542 https://reactome.org/PathwayBrowser/#/R-DRE-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Danio rerio 32682 R-DRE-70573 https://reactome.org/PathwayBrowser/#/R-DRE-70573 argininosuccinate <=> fumarate + arginine IEA Danio rerio 32682 R-DRE-71275 https://reactome.org/PathwayBrowser/#/R-DRE-71275 arginine + glycine => ornithine + guanidoacetate IEA Danio rerio 32682 R-DRE-8936442 https://reactome.org/PathwayBrowser/#/R-DRE-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Danio rerio 32682 R-DRE-8952726 https://reactome.org/PathwayBrowser/#/R-DRE-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Danio rerio 32682 R-DRE-8959781 https://reactome.org/PathwayBrowser/#/R-DRE-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Danio rerio 32682 R-DRE-9640167 https://reactome.org/PathwayBrowser/#/R-DRE-9640167 RRAGA,B exchanges GDP for GTP IEA Danio rerio 32682 R-DRE-9640168 https://reactome.org/PathwayBrowser/#/R-DRE-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Danio rerio 32682 R-DRE-9640175 https://reactome.org/PathwayBrowser/#/R-DRE-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Danio rerio 32682 R-GGA-187632 https://reactome.org/PathwayBrowser/#/R-GGA-187632 arginine + H2O => ornithine + urea TAS Gallus gallus 32682 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 32682 R-GGA-350598 https://reactome.org/PathwayBrowser/#/R-GGA-350598 Arginine<=>Agmatine+CO2 IEA Gallus gallus 32682 R-GGA-352136 https://reactome.org/PathwayBrowser/#/R-GGA-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Gallus gallus 32682 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 32682 R-GGA-375768 https://reactome.org/PathwayBrowser/#/R-GGA-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Gallus gallus 32682 R-GGA-375770 https://reactome.org/PathwayBrowser/#/R-GGA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Gallus gallus 32682 R-GGA-375776 https://reactome.org/PathwayBrowser/#/R-GGA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Gallus gallus 32682 R-GGA-375790 https://reactome.org/PathwayBrowser/#/R-GGA-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Gallus gallus 32682 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 32682 R-GGA-379432 https://reactome.org/PathwayBrowser/#/R-GGA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Gallus gallus 32682 R-GGA-418436 https://reactome.org/PathwayBrowser/#/R-GGA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Gallus gallus 32682 R-GGA-420739 https://reactome.org/PathwayBrowser/#/R-GGA-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Gallus gallus 32682 R-GGA-452036 https://reactome.org/PathwayBrowser/#/R-GGA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Gallus gallus 32682 R-GGA-70573 https://reactome.org/PathwayBrowser/#/R-GGA-70573 argininosuccinate <=> fumarate + arginine IEA Gallus gallus 32682 R-GGA-71275 https://reactome.org/PathwayBrowser/#/R-GGA-71275 arginine + glycine => ornithine + guanidoacetate IEA Gallus gallus 32682 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 32682 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 32682 R-GGA-8932851 https://reactome.org/PathwayBrowser/#/R-GGA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Gallus gallus 32682 R-GGA-8936442 https://reactome.org/PathwayBrowser/#/R-GGA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Gallus gallus 32682 R-GGA-8952726 https://reactome.org/PathwayBrowser/#/R-GGA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Gallus gallus 32682 R-GGA-8959781 https://reactome.org/PathwayBrowser/#/R-GGA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Gallus gallus 32682 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus 32682 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus 32682 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus 32682 R-GGA-9640237 https://reactome.org/PathwayBrowser/#/R-GGA-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Gallus gallus 32682 R-GGA-9657619 https://reactome.org/PathwayBrowser/#/R-GGA-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Gallus gallus 32682 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 32682 R-HSA-350598 https://reactome.org/PathwayBrowser/#/R-HSA-350598 Arginine<=>Agmatine+CO2 TAS Homo sapiens 32682 R-HSA-352136 https://reactome.org/PathwayBrowser/#/R-HSA-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine TAS Homo sapiens 32682 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 32682 R-HSA-375768 https://reactome.org/PathwayBrowser/#/R-HSA-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids TAS Homo sapiens 32682 R-HSA-375770 https://reactome.org/PathwayBrowser/#/R-HSA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids TAS Homo sapiens 32682 R-HSA-375776 https://reactome.org/PathwayBrowser/#/R-HSA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids TAS Homo sapiens 32682 R-HSA-375790 https://reactome.org/PathwayBrowser/#/R-HSA-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids TAS Homo sapiens 32682 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 32682 R-HSA-379415 https://reactome.org/PathwayBrowser/#/R-HSA-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane TAS Homo sapiens 32682 R-HSA-379426 https://reactome.org/PathwayBrowser/#/R-HSA-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine TAS Homo sapiens 32682 R-HSA-379432 https://reactome.org/PathwayBrowser/#/R-HSA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 32682 R-HSA-379993 https://reactome.org/PathwayBrowser/#/R-HSA-379993 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 32682 R-HSA-380224 https://reactome.org/PathwayBrowser/#/R-HSA-380224 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 32682 R-HSA-418436 https://reactome.org/PathwayBrowser/#/R-HSA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) TAS Homo sapiens 32682 R-HSA-420739 https://reactome.org/PathwayBrowser/#/R-HSA-420739 GPRC6A can bind L-alpha amino acids and calcium TAS Homo sapiens 32682 R-HSA-452036 https://reactome.org/PathwayBrowser/#/R-HSA-452036 arginine + H2O => ornithine + urea [ARG2] TAS Homo sapiens 32682 R-HSA-5655702 https://reactome.org/PathwayBrowser/#/R-HSA-5655702 Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 32682 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 32682 R-HSA-5660890 https://reactome.org/PathwayBrowser/#/R-HSA-5660890 Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 32682 R-HSA-5660910 https://reactome.org/PathwayBrowser/#/R-HSA-5660910 Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane TAS Homo sapiens 32682 R-HSA-5685345 https://reactome.org/PathwayBrowser/#/R-HSA-5685345 Formation of isoAsp TAS Homo sapiens 32682 R-HSA-70542 https://reactome.org/PathwayBrowser/#/R-HSA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA TAS Homo sapiens 32682 R-HSA-70569 https://reactome.org/PathwayBrowser/#/R-HSA-70569 arginine + H2O => ornithine + urea [ARG1] TAS Homo sapiens 32682 R-HSA-70573 https://reactome.org/PathwayBrowser/#/R-HSA-70573 argininosuccinate <=> fumarate + arginine TAS Homo sapiens 32682 R-HSA-71275 https://reactome.org/PathwayBrowser/#/R-HSA-71275 arginine + glycine => ornithine + guanidoacetate TAS Homo sapiens 32682 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 32682 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 32682 R-HSA-8932851 https://reactome.org/PathwayBrowser/#/R-HSA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol TAS Homo sapiens 32682 R-HSA-8936442 https://reactome.org/PathwayBrowser/#/R-HSA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds TAS Homo sapiens 32682 R-HSA-8952726 https://reactome.org/PathwayBrowser/#/R-HSA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol TAS Homo sapiens 32682 R-HSA-8959781 https://reactome.org/PathwayBrowser/#/R-HSA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix TAS Homo sapiens 32682 R-HSA-9023159 https://reactome.org/PathwayBrowser/#/R-HSA-9023159 Carboxypeptidase E hydrolyzes Insulin(57-89) to yield C-peptide (Insulin(57-87)) IEA Homo sapiens 32682 R-HSA-9640167 https://reactome.org/PathwayBrowser/#/R-HSA-9640167 RRAGA,B exchanges GDP for GTP TAS Homo sapiens 32682 R-HSA-9640168 https://reactome.org/PathwayBrowser/#/R-HSA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine TAS Homo sapiens 32682 R-HSA-9640175 https://reactome.org/PathwayBrowser/#/R-HSA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine TAS Homo sapiens 32682 R-HSA-9640237 https://reactome.org/PathwayBrowser/#/R-HSA-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 TAS Homo sapiens 32682 R-HSA-9657619 https://reactome.org/PathwayBrowser/#/R-HSA-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 TAS Homo sapiens 32682 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 32682 R-MMU-350598 https://reactome.org/PathwayBrowser/#/R-MMU-350598 Arginine<=>Agmatine+CO2 IEA Mus musculus 32682 R-MMU-352136 https://reactome.org/PathwayBrowser/#/R-MMU-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Mus musculus 32682 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 32682 R-MMU-375770 https://reactome.org/PathwayBrowser/#/R-MMU-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Mus musculus 32682 R-MMU-375776 https://reactome.org/PathwayBrowser/#/R-MMU-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Mus musculus 32682 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 32682 R-MMU-379415 https://reactome.org/PathwayBrowser/#/R-MMU-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Mus musculus 32682 R-MMU-379426 https://reactome.org/PathwayBrowser/#/R-MMU-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Mus musculus 32682 R-MMU-379432 https://reactome.org/PathwayBrowser/#/R-MMU-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Mus musculus 32682 R-MMU-418436 https://reactome.org/PathwayBrowser/#/R-MMU-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Mus musculus 32682 R-MMU-420739 https://reactome.org/PathwayBrowser/#/R-MMU-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Mus musculus 32682 R-MMU-452036 https://reactome.org/PathwayBrowser/#/R-MMU-452036 arginine + H2O => ornithine + urea [ARG2] IEA Mus musculus 32682 R-MMU-70542 https://reactome.org/PathwayBrowser/#/R-MMU-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Mus musculus 32682 R-MMU-70569 https://reactome.org/PathwayBrowser/#/R-MMU-70569 arginine + H2O => ornithine + urea [ARG1] IEA Mus musculus 32682 R-MMU-70573 https://reactome.org/PathwayBrowser/#/R-MMU-70573 argininosuccinate <=> fumarate + arginine IEA Mus musculus 32682 R-MMU-71275 https://reactome.org/PathwayBrowser/#/R-MMU-71275 arginine + glycine => ornithine + guanidoacetate IEA Mus musculus 32682 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 32682 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 32682 R-MMU-8932851 https://reactome.org/PathwayBrowser/#/R-MMU-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Mus musculus 32682 R-MMU-8936442 https://reactome.org/PathwayBrowser/#/R-MMU-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Mus musculus 32682 R-MMU-8952726 https://reactome.org/PathwayBrowser/#/R-MMU-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Mus musculus 32682 R-MMU-8959781 https://reactome.org/PathwayBrowser/#/R-MMU-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Mus musculus 32682 R-MMU-9640167 https://reactome.org/PathwayBrowser/#/R-MMU-9640167 RRAGA,B exchanges GDP for GTP IEA Mus musculus 32682 R-MMU-9640168 https://reactome.org/PathwayBrowser/#/R-MMU-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Mus musculus 32682 R-MMU-9640175 https://reactome.org/PathwayBrowser/#/R-MMU-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Mus musculus 32682 R-MMU-9640237 https://reactome.org/PathwayBrowser/#/R-MMU-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Mus musculus 32682 R-MMU-9657619 https://reactome.org/PathwayBrowser/#/R-MMU-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Mus musculus 32682 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 32682 R-PFA-350598 https://reactome.org/PathwayBrowser/#/R-PFA-350598 Arginine<=>Agmatine+CO2 IEA Plasmodium falciparum 32682 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 32682 R-PFA-418436 https://reactome.org/PathwayBrowser/#/R-PFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Plasmodium falciparum 32682 R-PFA-452036 https://reactome.org/PathwayBrowser/#/R-PFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Plasmodium falciparum 32682 R-PFA-70569 https://reactome.org/PathwayBrowser/#/R-PFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Plasmodium falciparum 32682 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 32682 R-RNO-350598 https://reactome.org/PathwayBrowser/#/R-RNO-350598 Arginine<=>Agmatine+CO2 IEA Rattus norvegicus 32682 R-RNO-352136 https://reactome.org/PathwayBrowser/#/R-RNO-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Rattus norvegicus 32682 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 32682 R-RNO-375770 https://reactome.org/PathwayBrowser/#/R-RNO-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Rattus norvegicus 32682 R-RNO-375776 https://reactome.org/PathwayBrowser/#/R-RNO-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Rattus norvegicus 32682 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 32682 R-RNO-379415 https://reactome.org/PathwayBrowser/#/R-RNO-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Rattus norvegicus 32682 R-RNO-379426 https://reactome.org/PathwayBrowser/#/R-RNO-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Rattus norvegicus 32682 R-RNO-379432 https://reactome.org/PathwayBrowser/#/R-RNO-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Rattus norvegicus 32682 R-RNO-418436 https://reactome.org/PathwayBrowser/#/R-RNO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Rattus norvegicus 32682 R-RNO-420739 https://reactome.org/PathwayBrowser/#/R-RNO-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Rattus norvegicus 32682 R-RNO-452036 https://reactome.org/PathwayBrowser/#/R-RNO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Rattus norvegicus 32682 R-RNO-70542 https://reactome.org/PathwayBrowser/#/R-RNO-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Rattus norvegicus 32682 R-RNO-70569 https://reactome.org/PathwayBrowser/#/R-RNO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Rattus norvegicus 32682 R-RNO-70573 https://reactome.org/PathwayBrowser/#/R-RNO-70573 argininosuccinate <=> fumarate + arginine IEA Rattus norvegicus 32682 R-RNO-71275 https://reactome.org/PathwayBrowser/#/R-RNO-71275 arginine + glycine => ornithine + guanidoacetate IEA Rattus norvegicus 32682 R-RNO-8932851 https://reactome.org/PathwayBrowser/#/R-RNO-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Rattus norvegicus 32682 R-RNO-8936442 https://reactome.org/PathwayBrowser/#/R-RNO-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Rattus norvegicus 32682 R-RNO-8952726 https://reactome.org/PathwayBrowser/#/R-RNO-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Rattus norvegicus 32682 R-RNO-8959781 https://reactome.org/PathwayBrowser/#/R-RNO-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Rattus norvegicus 32682 R-RNO-9640167 https://reactome.org/PathwayBrowser/#/R-RNO-9640167 RRAGA,B exchanges GDP for GTP IEA Rattus norvegicus 32682 R-RNO-9640168 https://reactome.org/PathwayBrowser/#/R-RNO-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Rattus norvegicus 32682 R-RNO-9640175 https://reactome.org/PathwayBrowser/#/R-RNO-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Rattus norvegicus 32682 R-RNO-9640237 https://reactome.org/PathwayBrowser/#/R-RNO-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Rattus norvegicus 32682 R-RNO-9657619 https://reactome.org/PathwayBrowser/#/R-RNO-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Rattus norvegicus 32682 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 32682 R-SCE-350598 https://reactome.org/PathwayBrowser/#/R-SCE-350598 Arginine<=>Agmatine+CO2 IEA Saccharomyces cerevisiae 32682 R-SCE-352136 https://reactome.org/PathwayBrowser/#/R-SCE-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Saccharomyces cerevisiae 32682 R-SCE-379432 https://reactome.org/PathwayBrowser/#/R-SCE-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Saccharomyces cerevisiae 32682 R-SCE-418436 https://reactome.org/PathwayBrowser/#/R-SCE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Saccharomyces cerevisiae 32682 R-SCE-452036 https://reactome.org/PathwayBrowser/#/R-SCE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Saccharomyces cerevisiae 32682 R-SCE-70542 https://reactome.org/PathwayBrowser/#/R-SCE-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Saccharomyces cerevisiae 32682 R-SCE-70569 https://reactome.org/PathwayBrowser/#/R-SCE-70569 arginine + H2O => ornithine + urea [ARG1] IEA Saccharomyces cerevisiae 32682 R-SCE-70573 https://reactome.org/PathwayBrowser/#/R-SCE-70573 argininosuccinate <=> fumarate + arginine IEA Saccharomyces cerevisiae 32682 R-SCE-8932851 https://reactome.org/PathwayBrowser/#/R-SCE-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Saccharomyces cerevisiae 32682 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 32682 R-SPO-350598 https://reactome.org/PathwayBrowser/#/R-SPO-350598 Arginine<=>Agmatine+CO2 IEA Schizosaccharomyces pombe 32682 R-SPO-418436 https://reactome.org/PathwayBrowser/#/R-SPO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Schizosaccharomyces pombe 32682 R-SPO-452036 https://reactome.org/PathwayBrowser/#/R-SPO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Schizosaccharomyces pombe 32682 R-SPO-70542 https://reactome.org/PathwayBrowser/#/R-SPO-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Schizosaccharomyces pombe 32682 R-SPO-70569 https://reactome.org/PathwayBrowser/#/R-SPO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Schizosaccharomyces pombe 32682 R-SPO-70573 https://reactome.org/PathwayBrowser/#/R-SPO-70573 argininosuccinate <=> fumarate + arginine IEA Schizosaccharomyces pombe 32682 R-SPO-8932851 https://reactome.org/PathwayBrowser/#/R-SPO-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Schizosaccharomyces pombe 32682 R-SPO-9640167 https://reactome.org/PathwayBrowser/#/R-SPO-9640167 RRAGA,B exchanges GDP for GTP IEA Schizosaccharomyces pombe 32682 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 32682 R-SSC-350598 https://reactome.org/PathwayBrowser/#/R-SSC-350598 Arginine<=>Agmatine+CO2 IEA Sus scrofa 32682 R-SSC-352136 https://reactome.org/PathwayBrowser/#/R-SSC-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Sus scrofa 32682 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 32682 R-SSC-375768 https://reactome.org/PathwayBrowser/#/R-SSC-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Sus scrofa 32682 R-SSC-375770 https://reactome.org/PathwayBrowser/#/R-SSC-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Sus scrofa 32682 R-SSC-375776 https://reactome.org/PathwayBrowser/#/R-SSC-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Sus scrofa 32682 R-SSC-375790 https://reactome.org/PathwayBrowser/#/R-SSC-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Sus scrofa 32682 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 32682 R-SSC-379415 https://reactome.org/PathwayBrowser/#/R-SSC-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Sus scrofa 32682 R-SSC-379432 https://reactome.org/PathwayBrowser/#/R-SSC-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Sus scrofa 32682 R-SSC-418436 https://reactome.org/PathwayBrowser/#/R-SSC-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Sus scrofa 32682 R-SSC-420739 https://reactome.org/PathwayBrowser/#/R-SSC-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Sus scrofa 32682 R-SSC-452036 https://reactome.org/PathwayBrowser/#/R-SSC-452036 arginine + H2O => ornithine + urea [ARG2] IEA Sus scrofa 32682 R-SSC-70542 https://reactome.org/PathwayBrowser/#/R-SSC-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Sus scrofa 32682 R-SSC-70569 https://reactome.org/PathwayBrowser/#/R-SSC-70569 arginine + H2O => ornithine + urea [ARG1] IEA Sus scrofa 32682 R-SSC-70573 https://reactome.org/PathwayBrowser/#/R-SSC-70573 argininosuccinate <=> fumarate + arginine IEA Sus scrofa 32682 R-SSC-71275 https://reactome.org/PathwayBrowser/#/R-SSC-71275 arginine + glycine => ornithine + guanidoacetate IEA Sus scrofa 32682 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 32682 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 32682 R-SSC-8932851 https://reactome.org/PathwayBrowser/#/R-SSC-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Sus scrofa 32682 R-SSC-8936442 https://reactome.org/PathwayBrowser/#/R-SSC-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Sus scrofa 32682 R-SSC-8952726 https://reactome.org/PathwayBrowser/#/R-SSC-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Sus scrofa 32682 R-SSC-9640167 https://reactome.org/PathwayBrowser/#/R-SSC-9640167 RRAGA,B exchanges GDP for GTP IEA Sus scrofa 32682 R-SSC-9640168 https://reactome.org/PathwayBrowser/#/R-SSC-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Sus scrofa 32682 R-SSC-9640175 https://reactome.org/PathwayBrowser/#/R-SSC-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Sus scrofa 32682 R-SSC-9640237 https://reactome.org/PathwayBrowser/#/R-SSC-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Sus scrofa 32682 R-SSC-9657619 https://reactome.org/PathwayBrowser/#/R-SSC-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Sus scrofa 32682 R-XTR-352136 https://reactome.org/PathwayBrowser/#/R-XTR-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine IEA Xenopus tropicalis 32682 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 32682 R-XTR-375768 https://reactome.org/PathwayBrowser/#/R-XTR-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 32682 R-XTR-375770 https://reactome.org/PathwayBrowser/#/R-XTR-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 32682 R-XTR-375776 https://reactome.org/PathwayBrowser/#/R-XTR-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 32682 R-XTR-375790 https://reactome.org/PathwayBrowser/#/R-XTR-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 32682 R-XTR-379415 https://reactome.org/PathwayBrowser/#/R-XTR-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Xenopus tropicalis 32682 R-XTR-379426 https://reactome.org/PathwayBrowser/#/R-XTR-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Xenopus tropicalis 32682 R-XTR-379432 https://reactome.org/PathwayBrowser/#/R-XTR-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Xenopus tropicalis 32682 R-XTR-420739 https://reactome.org/PathwayBrowser/#/R-XTR-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Xenopus tropicalis 32682 R-XTR-452036 https://reactome.org/PathwayBrowser/#/R-XTR-452036 arginine + H2O => ornithine + urea [ARG2] IEA Xenopus tropicalis 32682 R-XTR-70542 https://reactome.org/PathwayBrowser/#/R-XTR-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Xenopus tropicalis 32682 R-XTR-70569 https://reactome.org/PathwayBrowser/#/R-XTR-70569 arginine + H2O => ornithine + urea [ARG1] IEA Xenopus tropicalis 32682 R-XTR-70573 https://reactome.org/PathwayBrowser/#/R-XTR-70573 argininosuccinate <=> fumarate + arginine IEA Xenopus tropicalis 32682 R-XTR-71275 https://reactome.org/PathwayBrowser/#/R-XTR-71275 arginine + glycine => ornithine + guanidoacetate IEA Xenopus tropicalis 32682 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 32682 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 32682 R-XTR-8932851 https://reactome.org/PathwayBrowser/#/R-XTR-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol IEA Xenopus tropicalis 32682 R-XTR-8936442 https://reactome.org/PathwayBrowser/#/R-XTR-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Xenopus tropicalis 32682 R-XTR-8952726 https://reactome.org/PathwayBrowser/#/R-XTR-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Xenopus tropicalis 32682 R-XTR-8959781 https://reactome.org/PathwayBrowser/#/R-XTR-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Xenopus tropicalis 32682 R-XTR-9640167 https://reactome.org/PathwayBrowser/#/R-XTR-9640167 RRAGA,B exchanges GDP for GTP IEA Xenopus tropicalis 32682 R-XTR-9640168 https://reactome.org/PathwayBrowser/#/R-XTR-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Xenopus tropicalis 32682 R-XTR-9640175 https://reactome.org/PathwayBrowser/#/R-XTR-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Xenopus tropicalis 32682 R-XTR-9640237 https://reactome.org/PathwayBrowser/#/R-XTR-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Xenopus tropicalis 32682 R-XTR-9657619 https://reactome.org/PathwayBrowser/#/R-XTR-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Xenopus tropicalis 32701 R-BTA-158860 https://reactome.org/PathwayBrowser/#/R-BTA-158860 SULT1A1 dimer sulfonates NHABP IEA Bos taurus 32701 R-CFA-158860 https://reactome.org/PathwayBrowser/#/R-CFA-158860 SULT1A1 dimer sulfonates NHABP IEA Canis familiaris 32701 R-DME-158860 https://reactome.org/PathwayBrowser/#/R-DME-158860 SULT1A1 dimer sulfonates NHABP IEA Drosophila melanogaster 32701 R-DRE-158860 https://reactome.org/PathwayBrowser/#/R-DRE-158860 SULT1A1 dimer sulfonates NHABP IEA Danio rerio 32701 R-GGA-158860 https://reactome.org/PathwayBrowser/#/R-GGA-158860 SULT1A1 dimer sulfonates NHABP IEA Gallus gallus 32701 R-HSA-158860 https://reactome.org/PathwayBrowser/#/R-HSA-158860 SULT1A1 dimer sulfonates NHABP TAS Homo sapiens 32701 R-MMU-158860 https://reactome.org/PathwayBrowser/#/R-MMU-158860 SULT1A1 dimer sulfonates NHABP IEA Mus musculus 32701 R-RNO-158860 https://reactome.org/PathwayBrowser/#/R-RNO-158860 SULT1A1 dimer sulfonates NHABP IEA Rattus norvegicus 32701 R-SSC-158860 https://reactome.org/PathwayBrowser/#/R-SSC-158860 SULT1A1 dimer sulfonates NHABP IEA Sus scrofa 32701 R-XTR-158860 https://reactome.org/PathwayBrowser/#/R-XTR-158860 SULT1A1 dimer sulfonates NHABP IEA Xenopus tropicalis 32796 R-BTA-880002 https://reactome.org/PathwayBrowser/#/R-BTA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Bos taurus 32796 R-BTA-880007 https://reactome.org/PathwayBrowser/#/R-BTA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Bos taurus 32796 R-BTA-880033 https://reactome.org/PathwayBrowser/#/R-BTA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Bos taurus 32796 R-CEL-880002 https://reactome.org/PathwayBrowser/#/R-CEL-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Caenorhabditis elegans 32796 R-CEL-880007 https://reactome.org/PathwayBrowser/#/R-CEL-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Caenorhabditis elegans 32796 R-CEL-880033 https://reactome.org/PathwayBrowser/#/R-CEL-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Caenorhabditis elegans 32796 R-CFA-880002 https://reactome.org/PathwayBrowser/#/R-CFA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Canis familiaris 32796 R-CFA-880007 https://reactome.org/PathwayBrowser/#/R-CFA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Canis familiaris 32796 R-CFA-880033 https://reactome.org/PathwayBrowser/#/R-CFA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Canis familiaris 32796 R-DDI-880002 https://reactome.org/PathwayBrowser/#/R-DDI-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Dictyostelium discoideum 32796 R-DDI-880007 https://reactome.org/PathwayBrowser/#/R-DDI-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Dictyostelium discoideum 32796 R-DDI-880033 https://reactome.org/PathwayBrowser/#/R-DDI-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Dictyostelium discoideum 32796 R-DME-880002 https://reactome.org/PathwayBrowser/#/R-DME-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Drosophila melanogaster 32796 R-DME-880007 https://reactome.org/PathwayBrowser/#/R-DME-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Drosophila melanogaster 32796 R-DME-880033 https://reactome.org/PathwayBrowser/#/R-DME-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Drosophila melanogaster 32796 R-DRE-880002 https://reactome.org/PathwayBrowser/#/R-DRE-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Danio rerio 32796 R-DRE-880007 https://reactome.org/PathwayBrowser/#/R-DRE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Danio rerio 32796 R-DRE-880033 https://reactome.org/PathwayBrowser/#/R-DRE-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Danio rerio 32796 R-GGA-880002 https://reactome.org/PathwayBrowser/#/R-GGA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Gallus gallus 32796 R-GGA-880007 https://reactome.org/PathwayBrowser/#/R-GGA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus 32796 R-GGA-880033 https://reactome.org/PathwayBrowser/#/R-GGA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Gallus gallus 32796 R-HSA-880002 https://reactome.org/PathwayBrowser/#/R-HSA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate TAS Homo sapiens 32796 R-HSA-880007 https://reactome.org/PathwayBrowser/#/R-HSA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 TAS Homo sapiens 32796 R-HSA-880033 https://reactome.org/PathwayBrowser/#/R-HSA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde TAS Homo sapiens 32796 R-HSA-880053 https://reactome.org/PathwayBrowser/#/R-HSA-880053 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] TAS Homo sapiens 32796 R-MMU-880002 https://reactome.org/PathwayBrowser/#/R-MMU-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Mus musculus 32796 R-MMU-880007 https://reactome.org/PathwayBrowser/#/R-MMU-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Mus musculus 32796 R-MMU-880033 https://reactome.org/PathwayBrowser/#/R-MMU-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Mus musculus 32796 R-RNO-880002 https://reactome.org/PathwayBrowser/#/R-RNO-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Rattus norvegicus 32796 R-RNO-880007 https://reactome.org/PathwayBrowser/#/R-RNO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Rattus norvegicus 32796 R-RNO-880033 https://reactome.org/PathwayBrowser/#/R-RNO-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Rattus norvegicus 32796 R-SCE-880007 https://reactome.org/PathwayBrowser/#/R-SCE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Saccharomyces cerevisiae 32796 R-SPO-880007 https://reactome.org/PathwayBrowser/#/R-SPO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Schizosaccharomyces pombe 32796 R-SSC-880002 https://reactome.org/PathwayBrowser/#/R-SSC-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Sus scrofa 32796 R-SSC-880007 https://reactome.org/PathwayBrowser/#/R-SSC-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa 32796 R-SSC-880033 https://reactome.org/PathwayBrowser/#/R-SSC-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Sus scrofa 32796 R-XTR-880002 https://reactome.org/PathwayBrowser/#/R-XTR-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Xenopus tropicalis 32796 R-XTR-880007 https://reactome.org/PathwayBrowser/#/R-XTR-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Xenopus tropicalis 32796 R-XTR-880033 https://reactome.org/PathwayBrowser/#/R-XTR-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Xenopus tropicalis 32797 R-BTA-880050 https://reactome.org/PathwayBrowser/#/R-BTA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Bos taurus 32797 R-CEL-880050 https://reactome.org/PathwayBrowser/#/R-CEL-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Caenorhabditis elegans 32797 R-CFA-880050 https://reactome.org/PathwayBrowser/#/R-CFA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Canis familiaris 32797 R-DDI-880050 https://reactome.org/PathwayBrowser/#/R-DDI-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Dictyostelium discoideum 32797 R-DME-880050 https://reactome.org/PathwayBrowser/#/R-DME-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Drosophila melanogaster 32797 R-GGA-880050 https://reactome.org/PathwayBrowser/#/R-GGA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus 32797 R-HSA-880050 https://reactome.org/PathwayBrowser/#/R-HSA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 TAS Homo sapiens 32797 R-MMU-880050 https://reactome.org/PathwayBrowser/#/R-MMU-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Mus musculus 32797 R-RNO-880050 https://reactome.org/PathwayBrowser/#/R-RNO-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Rattus norvegicus 32797 R-SSC-880050 https://reactome.org/PathwayBrowser/#/R-SSC-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa 32797 R-XTR-880050 https://reactome.org/PathwayBrowser/#/R-XTR-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Xenopus tropicalis 32812 R-BTA-6784393 https://reactome.org/PathwayBrowser/#/R-BTA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Bos taurus 32812 R-BTA-6784399 https://reactome.org/PathwayBrowser/#/R-BTA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Bos taurus 32812 R-CEL-6784393 https://reactome.org/PathwayBrowser/#/R-CEL-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Caenorhabditis elegans 32812 R-CFA-6784393 https://reactome.org/PathwayBrowser/#/R-CFA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Canis familiaris 32812 R-CFA-6784399 https://reactome.org/PathwayBrowser/#/R-CFA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Canis familiaris 32812 R-DDI-6784393 https://reactome.org/PathwayBrowser/#/R-DDI-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Dictyostelium discoideum 32812 R-DME-6784393 https://reactome.org/PathwayBrowser/#/R-DME-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Drosophila melanogaster 32812 R-DRE-6784393 https://reactome.org/PathwayBrowser/#/R-DRE-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Danio rerio 32812 R-DRE-6784399 https://reactome.org/PathwayBrowser/#/R-DRE-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Danio rerio 32812 R-GGA-6784393 https://reactome.org/PathwayBrowser/#/R-GGA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Gallus gallus 32812 R-GGA-6784399 https://reactome.org/PathwayBrowser/#/R-GGA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Gallus gallus 32812 R-HSA-6784393 https://reactome.org/PathwayBrowser/#/R-HSA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) TAS Homo sapiens 32812 R-HSA-6784399 https://reactome.org/PathwayBrowser/#/R-HSA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate TAS Homo sapiens 32812 R-MMU-6784393 https://reactome.org/PathwayBrowser/#/R-MMU-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Mus musculus 32812 R-MMU-6784399 https://reactome.org/PathwayBrowser/#/R-MMU-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Mus musculus 32812 R-RNO-6784393 https://reactome.org/PathwayBrowser/#/R-RNO-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Rattus norvegicus 32812 R-RNO-6784399 https://reactome.org/PathwayBrowser/#/R-RNO-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Rattus norvegicus 32812 R-SCE-6784393 https://reactome.org/PathwayBrowser/#/R-SCE-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Saccharomyces cerevisiae 32812 R-SPO-6784393 https://reactome.org/PathwayBrowser/#/R-SPO-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Schizosaccharomyces pombe 32812 R-SSC-6784393 https://reactome.org/PathwayBrowser/#/R-SSC-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Sus scrofa 32812 R-SSC-6784399 https://reactome.org/PathwayBrowser/#/R-SSC-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Sus scrofa 32812 R-XTR-6784393 https://reactome.org/PathwayBrowser/#/R-XTR-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Xenopus tropicalis 32812 R-XTR-6784399 https://reactome.org/PathwayBrowser/#/R-XTR-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Xenopus tropicalis 32814 R-BTA-73571 https://reactome.org/PathwayBrowser/#/R-BTA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Bos taurus 32814 R-BTA-73573 https://reactome.org/PathwayBrowser/#/R-BTA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Bos taurus 32814 R-CEL-73571 https://reactome.org/PathwayBrowser/#/R-CEL-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Caenorhabditis elegans 32814 R-CEL-73573 https://reactome.org/PathwayBrowser/#/R-CEL-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Caenorhabditis elegans 32814 R-CFA-73571 https://reactome.org/PathwayBrowser/#/R-CFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Canis familiaris 32814 R-CFA-73573 https://reactome.org/PathwayBrowser/#/R-CFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Canis familiaris 32814 R-DDI-73571 https://reactome.org/PathwayBrowser/#/R-DDI-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Dictyostelium discoideum 32814 R-DDI-73573 https://reactome.org/PathwayBrowser/#/R-DDI-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Dictyostelium discoideum 32814 R-DME-73571 https://reactome.org/PathwayBrowser/#/R-DME-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Drosophila melanogaster 32814 R-DME-73573 https://reactome.org/PathwayBrowser/#/R-DME-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Drosophila melanogaster 32814 R-GGA-419451 https://reactome.org/PathwayBrowser/#/R-GGA-419451 carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate IEA Gallus gallus 32814 R-GGA-419465 https://reactome.org/PathwayBrowser/#/R-GGA-419465 N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O IEA Gallus gallus 32814 R-HSA-73571 https://reactome.org/PathwayBrowser/#/R-HSA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO TAS Homo sapiens 32814 R-HSA-73573 https://reactome.org/PathwayBrowser/#/R-HSA-73573 CAD hexamer transforms CAP to N-carb-L-Asp TAS Homo sapiens 32814 R-MMU-73571 https://reactome.org/PathwayBrowser/#/R-MMU-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Mus musculus 32814 R-MMU-73573 https://reactome.org/PathwayBrowser/#/R-MMU-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Mus musculus 32814 R-PFA-73571 https://reactome.org/PathwayBrowser/#/R-PFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Plasmodium falciparum 32814 R-PFA-73573 https://reactome.org/PathwayBrowser/#/R-PFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Plasmodium falciparum 32814 R-RNO-73571 https://reactome.org/PathwayBrowser/#/R-RNO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Rattus norvegicus 32814 R-RNO-73573 https://reactome.org/PathwayBrowser/#/R-RNO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Rattus norvegicus 32814 R-SCE-73571 https://reactome.org/PathwayBrowser/#/R-SCE-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Saccharomyces cerevisiae 32814 R-SCE-73573 https://reactome.org/PathwayBrowser/#/R-SCE-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Saccharomyces cerevisiae 32814 R-SPO-73571 https://reactome.org/PathwayBrowser/#/R-SPO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Schizosaccharomyces pombe 32814 R-SPO-73573 https://reactome.org/PathwayBrowser/#/R-SPO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Schizosaccharomyces pombe 32814 R-SSC-73571 https://reactome.org/PathwayBrowser/#/R-SSC-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Sus scrofa 32814 R-SSC-73573 https://reactome.org/PathwayBrowser/#/R-SSC-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Sus scrofa 32814 R-XTR-73571 https://reactome.org/PathwayBrowser/#/R-XTR-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Xenopus tropicalis 32814 R-XTR-73573 https://reactome.org/PathwayBrowser/#/R-XTR-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Xenopus tropicalis 32966 R-BTA-111524 https://reactome.org/PathwayBrowser/#/R-BTA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Bos taurus 32966 R-BTA-70467 https://reactome.org/PathwayBrowser/#/R-BTA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Bos taurus 32966 R-BTA-70479 https://reactome.org/PathwayBrowser/#/R-BTA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Bos taurus 32966 R-BTA-71495 https://reactome.org/PathwayBrowser/#/R-BTA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Bos taurus 32966 R-BTA-71496 https://reactome.org/PathwayBrowser/#/R-BTA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 32966 R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 32966 R-CEL-111524 https://reactome.org/PathwayBrowser/#/R-CEL-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Caenorhabditis elegans 32966 R-CEL-70467 https://reactome.org/PathwayBrowser/#/R-CEL-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Caenorhabditis elegans 32966 R-CEL-70479 https://reactome.org/PathwayBrowser/#/R-CEL-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Caenorhabditis elegans 32966 R-CEL-71495 https://reactome.org/PathwayBrowser/#/R-CEL-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Caenorhabditis elegans 32966 R-CEL-71496 https://reactome.org/PathwayBrowser/#/R-CEL-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 32966 R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 32966 R-CFA-111524 https://reactome.org/PathwayBrowser/#/R-CFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Canis familiaris 32966 R-CFA-70467 https://reactome.org/PathwayBrowser/#/R-CFA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Canis familiaris 32966 R-CFA-70479 https://reactome.org/PathwayBrowser/#/R-CFA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Canis familiaris 32966 R-CFA-71495 https://reactome.org/PathwayBrowser/#/R-CFA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Canis familiaris 32966 R-CFA-71496 https://reactome.org/PathwayBrowser/#/R-CFA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 32966 R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 32966 R-DDI-111524 https://reactome.org/PathwayBrowser/#/R-DDI-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Dictyostelium discoideum 32966 R-DDI-70479 https://reactome.org/PathwayBrowser/#/R-DDI-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Dictyostelium discoideum 32966 R-DDI-71495 https://reactome.org/PathwayBrowser/#/R-DDI-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Dictyostelium discoideum 32966 R-DDI-71496 https://reactome.org/PathwayBrowser/#/R-DDI-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 32966 R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 32966 R-DME-111524 https://reactome.org/PathwayBrowser/#/R-DME-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Drosophila melanogaster 32966 R-DME-70467 https://reactome.org/PathwayBrowser/#/R-DME-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Drosophila melanogaster 32966 R-DME-70479 https://reactome.org/PathwayBrowser/#/R-DME-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Drosophila melanogaster 32966 R-DME-71495 https://reactome.org/PathwayBrowser/#/R-DME-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Drosophila melanogaster 32966 R-DME-71496 https://reactome.org/PathwayBrowser/#/R-DME-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 32966 R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 32966 R-DRE-111524 https://reactome.org/PathwayBrowser/#/R-DRE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Danio rerio 32966 R-DRE-70467 https://reactome.org/PathwayBrowser/#/R-DRE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Danio rerio 32966 R-DRE-70479 https://reactome.org/PathwayBrowser/#/R-DRE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Danio rerio 32966 R-DRE-71495 https://reactome.org/PathwayBrowser/#/R-DRE-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Danio rerio 32966 R-DRE-71496 https://reactome.org/PathwayBrowser/#/R-DRE-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Danio rerio 32966 R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 32966 R-GGA-111524 https://reactome.org/PathwayBrowser/#/R-GGA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Gallus gallus 32966 R-GGA-352945 https://reactome.org/PathwayBrowser/#/R-GGA-352945 fructose 6-phosphate + ATP => fructose 1,6-bisphosphate + ADP TAS Gallus gallus 32966 R-GGA-352946 https://reactome.org/PathwayBrowser/#/R-GGA-352946 fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate TAS Gallus gallus 32966 R-GGA-352961 https://reactome.org/PathwayBrowser/#/R-GGA-352961 dihydroxyacetone phosphate + glyceraldehyde 3-phosphate <=> fructose 1,6-bisphosphate TAS Gallus gallus 32966 R-GGA-372388 https://reactome.org/PathwayBrowser/#/R-GGA-372388 fructose 1,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate TAS Gallus gallus 32966 R-GGA-70467 https://reactome.org/PathwayBrowser/#/R-GGA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Gallus gallus 32966 R-GGA-70479 https://reactome.org/PathwayBrowser/#/R-GGA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Gallus gallus 32966 R-GGA-71495 https://reactome.org/PathwayBrowser/#/R-GGA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Gallus gallus 32966 R-GGA-71496 https://reactome.org/PathwayBrowser/#/R-GGA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 32966 R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 32966 R-HSA-111524 https://reactome.org/PathwayBrowser/#/R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] TAS Homo sapiens 32966 R-HSA-70467 https://reactome.org/PathwayBrowser/#/R-HSA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP TAS Homo sapiens 32966 R-HSA-70479 https://reactome.org/PathwayBrowser/#/R-HSA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P TAS Homo sapiens 32966 R-HSA-71495 https://reactome.org/PathwayBrowser/#/R-HSA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP TAS Homo sapiens 32966 R-HSA-71496 https://reactome.org/PathwayBrowser/#/R-HSA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 32966 R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 32966 R-MMU-111519 https://reactome.org/PathwayBrowser/#/R-MMU-111519 inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate TAS Mus musculus 32966 R-MMU-111524 https://reactome.org/PathwayBrowser/#/R-MMU-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Mus musculus 32966 R-MMU-70467 https://reactome.org/PathwayBrowser/#/R-MMU-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Mus musculus 32966 R-MMU-70479 https://reactome.org/PathwayBrowser/#/R-MMU-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Mus musculus 32966 R-MMU-71495 https://reactome.org/PathwayBrowser/#/R-MMU-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Mus musculus 32966 R-MMU-71496 https://reactome.org/PathwayBrowser/#/R-MMU-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 32966 R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 32966 R-PFA-111524 https://reactome.org/PathwayBrowser/#/R-PFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Plasmodium falciparum 32966 R-PFA-71495 https://reactome.org/PathwayBrowser/#/R-PFA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Plasmodium falciparum 32966 R-PFA-71496 https://reactome.org/PathwayBrowser/#/R-PFA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Plasmodium falciparum 32966 R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 32966 R-RNO-111524 https://reactome.org/PathwayBrowser/#/R-RNO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Rattus norvegicus 32966 R-RNO-70467 https://reactome.org/PathwayBrowser/#/R-RNO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Rattus norvegicus 32966 R-RNO-70479 https://reactome.org/PathwayBrowser/#/R-RNO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Rattus norvegicus 32966 R-RNO-71495 https://reactome.org/PathwayBrowser/#/R-RNO-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Rattus norvegicus 32966 R-RNO-71496 https://reactome.org/PathwayBrowser/#/R-RNO-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 32966 R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 32966 R-SCE-111524 https://reactome.org/PathwayBrowser/#/R-SCE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Saccharomyces cerevisiae 32966 R-SCE-70467 https://reactome.org/PathwayBrowser/#/R-SCE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 32966 R-SCE-70479 https://reactome.org/PathwayBrowser/#/R-SCE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Saccharomyces cerevisiae 32966 R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 32966 R-SPO-111524 https://reactome.org/PathwayBrowser/#/R-SPO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Schizosaccharomyces pombe 32966 R-SPO-70467 https://reactome.org/PathwayBrowser/#/R-SPO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 32966 R-SPO-70479 https://reactome.org/PathwayBrowser/#/R-SPO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Schizosaccharomyces pombe 32966 R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 32966 R-SSC-111524 https://reactome.org/PathwayBrowser/#/R-SSC-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Sus scrofa 32966 R-SSC-70467 https://reactome.org/PathwayBrowser/#/R-SSC-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Sus scrofa 32966 R-SSC-70479 https://reactome.org/PathwayBrowser/#/R-SSC-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Sus scrofa 32966 R-SSC-71495 https://reactome.org/PathwayBrowser/#/R-SSC-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Sus scrofa 32966 R-SSC-71496 https://reactome.org/PathwayBrowser/#/R-SSC-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 32966 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 32966 R-XTR-111524 https://reactome.org/PathwayBrowser/#/R-XTR-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Xenopus tropicalis 32966 R-XTR-70479 https://reactome.org/PathwayBrowser/#/R-XTR-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Xenopus tropicalis 32966 R-XTR-71495 https://reactome.org/PathwayBrowser/#/R-XTR-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Xenopus tropicalis 32966 R-XTR-71496 https://reactome.org/PathwayBrowser/#/R-XTR-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 32966 R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 33019 R-BTA-110311 https://reactome.org/PathwayBrowser/#/R-BTA-110311 POLZ extends translesion synthesis IEA Bos taurus 33019 R-BTA-110317 https://reactome.org/PathwayBrowser/#/R-BTA-110317 Insertion of correct bases opposite the lesion by POLH IEA Bos taurus 33019 R-BTA-110319 https://reactome.org/PathwayBrowser/#/R-BTA-110319 Elongation by POLH IEA Bos taurus 33019 R-BTA-110368 https://reactome.org/PathwayBrowser/#/R-BTA-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Bos taurus 33019 R-BTA-111253 https://reactome.org/PathwayBrowser/#/R-BTA-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Bos taurus 33019 R-BTA-111264 https://reactome.org/PathwayBrowser/#/R-BTA-111264 Addition of nucleotides between position +11 and +30 IEA Bos taurus 33019 R-BTA-111930 https://reactome.org/PathwayBrowser/#/R-BTA-111930 Adenylate cyclase produces cAMP IEA Bos taurus 33019 R-BTA-1169394 https://reactome.org/PathwayBrowser/#/R-BTA-1169394 ISGylation of IRF3 IEA Bos taurus 33019 R-BTA-1169397 https://reactome.org/PathwayBrowser/#/R-BTA-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Bos taurus 33019 R-BTA-1169398 https://reactome.org/PathwayBrowser/#/R-BTA-1169398 ISGylation of host protein filamin B IEA Bos taurus 33019 R-BTA-1169402 https://reactome.org/PathwayBrowser/#/R-BTA-1169402 ISGylation of E2 conjugating enzymes IEA Bos taurus 33019 R-BTA-1169405 https://reactome.org/PathwayBrowser/#/R-BTA-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Bos taurus 33019 R-BTA-1169406 https://reactome.org/PathwayBrowser/#/R-BTA-1169406 ISGylation of host proteins IEA Bos taurus 33019 R-BTA-1483081 https://reactome.org/PathwayBrowser/#/R-BTA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Bos taurus 33019 R-BTA-1483121 https://reactome.org/PathwayBrowser/#/R-BTA-1483121 PA is converted to CDP-DAG by CDS1 IEA Bos taurus 33019 R-BTA-1483165 https://reactome.org/PathwayBrowser/#/R-BTA-1483165 PA is converted to CDP-DAG by CDS2 IEA Bos taurus 33019 R-BTA-1483190 https://reactome.org/PathwayBrowser/#/R-BTA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Bos taurus 33019 R-BTA-159425 https://reactome.org/PathwayBrowser/#/R-BTA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 33019 R-BTA-159443 https://reactome.org/PathwayBrowser/#/R-BTA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Bos taurus 33019 R-BTA-159567 https://reactome.org/PathwayBrowser/#/R-BTA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Bos taurus 33019 R-BTA-170676 https://reactome.org/PathwayBrowser/#/R-BTA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Bos taurus 33019 R-BTA-174124 https://reactome.org/PathwayBrowser/#/R-BTA-174124 Dephosphorylation of phospho-Cdh1 IEA Bos taurus 33019 R-BTA-174391 https://reactome.org/PathwayBrowser/#/R-BTA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Bos taurus 33019 R-BTA-174392 https://reactome.org/PathwayBrowser/#/R-BTA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Bos taurus 33019 R-BTA-177157 https://reactome.org/PathwayBrowser/#/R-BTA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Bos taurus 33019 R-BTA-191402 https://reactome.org/PathwayBrowser/#/R-BTA-191402 Reduction of presqualene diphosphate to form squalene IEA Bos taurus 33019 R-BTA-191405 https://reactome.org/PathwayBrowser/#/R-BTA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Bos taurus 33019 R-BTA-192137 https://reactome.org/PathwayBrowser/#/R-BTA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 33019 R-BTA-193401 https://reactome.org/PathwayBrowser/#/R-BTA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 33019 R-BTA-193407 https://reactome.org/PathwayBrowser/#/R-BTA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 33019 R-BTA-193424 https://reactome.org/PathwayBrowser/#/R-BTA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 33019 R-BTA-193711 https://reactome.org/PathwayBrowser/#/R-BTA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 33019 R-BTA-193727 https://reactome.org/PathwayBrowser/#/R-BTA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 33019 R-BTA-193743 https://reactome.org/PathwayBrowser/#/R-BTA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 33019 R-BTA-193766 https://reactome.org/PathwayBrowser/#/R-BTA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 33019 R-BTA-196753 https://reactome.org/PathwayBrowser/#/R-BTA-196753 2xPPCS ligates PPanK with Cys IEA Bos taurus 33019 R-BTA-196754 https://reactome.org/PathwayBrowser/#/R-BTA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Bos taurus 33019 R-BTA-196929 https://reactome.org/PathwayBrowser/#/R-BTA-196929 FLAD1 phosphorylates FMN IEA Bos taurus 33019 R-BTA-197186 https://reactome.org/PathwayBrowser/#/R-BTA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Bos taurus 33019 R-BTA-197235 https://reactome.org/PathwayBrowser/#/R-BTA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 33019 R-BTA-197250 https://reactome.org/PathwayBrowser/#/R-BTA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Bos taurus 33019 R-BTA-197268 https://reactome.org/PathwayBrowser/#/R-BTA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Bos taurus 33019 R-BTA-197271 https://reactome.org/PathwayBrowser/#/R-BTA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Bos taurus 33019 R-BTA-200474 https://reactome.org/PathwayBrowser/#/R-BTA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 33019 R-BTA-200512 https://reactome.org/PathwayBrowser/#/R-BTA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 33019 R-BTA-201035 https://reactome.org/PathwayBrowser/#/R-BTA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Bos taurus 33019 R-BTA-2046085 https://reactome.org/PathwayBrowser/#/R-BTA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Bos taurus 33019 R-BTA-2046098 https://reactome.org/PathwayBrowser/#/R-BTA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Bos taurus 33019 R-BTA-2162192 https://reactome.org/PathwayBrowser/#/R-BTA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Bos taurus 33019 R-BTA-2162253 https://reactome.org/PathwayBrowser/#/R-BTA-2162253 PDSS1,2 ligates FPP to IPPP IEA Bos taurus 33019 R-BTA-2395818 https://reactome.org/PathwayBrowser/#/R-BTA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Bos taurus 33019 R-BTA-2395849 https://reactome.org/PathwayBrowser/#/R-BTA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 33019 R-BTA-2395869 https://reactome.org/PathwayBrowser/#/R-BTA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 33019 R-BTA-2395872 https://reactome.org/PathwayBrowser/#/R-BTA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Bos taurus 33019 R-BTA-2408551 https://reactome.org/PathwayBrowser/#/R-BTA-2408551 SeMet is converted to AdoSeMet by MAT IEA Bos taurus 33019 R-BTA-2509827 https://reactome.org/PathwayBrowser/#/R-BTA-2509827 ITPA hydrolyses ITP to IMP IEA Bos taurus 33019 R-BTA-2509831 https://reactome.org/PathwayBrowser/#/R-BTA-2509831 ITPA hydrolyses XTP to XMP IEA Bos taurus 33019 R-BTA-2509838 https://reactome.org/PathwayBrowser/#/R-BTA-2509838 ITPA hydrolyses dITP to dIMP IEA Bos taurus 33019 R-BTA-2530501 https://reactome.org/PathwayBrowser/#/R-BTA-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Bos taurus 33019 R-BTA-2990833 https://reactome.org/PathwayBrowser/#/R-BTA-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Bos taurus 33019 R-BTA-2993447 https://reactome.org/PathwayBrowser/#/R-BTA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Bos taurus 33019 R-BTA-2993799 https://reactome.org/PathwayBrowser/#/R-BTA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Bos taurus 33019 R-BTA-2993802 https://reactome.org/PathwayBrowser/#/R-BTA-2993802 HLCS biotinylates PC:Mn2+ IEA Bos taurus 33019 R-BTA-2993814 https://reactome.org/PathwayBrowser/#/R-BTA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Bos taurus 33019 R-BTA-2995330 https://reactome.org/PathwayBrowser/#/R-BTA-2995330 COX10 transforms heme to heme O IEA Bos taurus 33019 R-BTA-389622 https://reactome.org/PathwayBrowser/#/R-BTA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 33019 R-BTA-389632 https://reactome.org/PathwayBrowser/#/R-BTA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 33019 R-BTA-389758 https://reactome.org/PathwayBrowser/#/R-BTA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Bos taurus 33019 R-BTA-392513 https://reactome.org/PathwayBrowser/#/R-BTA-392513 Rap1 signal termination by Rap1GAPs IEA Bos taurus 33019 R-BTA-4084982 https://reactome.org/PathwayBrowser/#/R-BTA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Bos taurus 33019 R-BTA-4167511 https://reactome.org/PathwayBrowser/#/R-BTA-4167511 HLCS biotinylates ACACB IEA Bos taurus 33019 R-BTA-434382 https://reactome.org/PathwayBrowser/#/R-BTA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Bos taurus 33019 R-BTA-446204 https://reactome.org/PathwayBrowser/#/R-BTA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Bos taurus 33019 R-BTA-449911 https://reactome.org/PathwayBrowser/#/R-BTA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Bos taurus 33019 R-BTA-449937 https://reactome.org/PathwayBrowser/#/R-BTA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Bos taurus 33019 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 33019 R-BTA-5226964 https://reactome.org/PathwayBrowser/#/R-BTA-5226964 ANKH transports PPi from cytosol to extracellular region IEA Bos taurus 33019 R-BTA-5358475 https://reactome.org/PathwayBrowser/#/R-BTA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Bos taurus 33019 R-BTA-5358592 https://reactome.org/PathwayBrowser/#/R-BTA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Bos taurus 33019 R-BTA-548843 https://reactome.org/PathwayBrowser/#/R-BTA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Bos taurus 33019 R-BTA-5603114 https://reactome.org/PathwayBrowser/#/R-BTA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Bos taurus 33019 R-BTA-5610727 https://reactome.org/PathwayBrowser/#/R-BTA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Bos taurus 33019 R-BTA-5649723 https://reactome.org/PathwayBrowser/#/R-BTA-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Bos taurus 33019 R-BTA-5649883 https://reactome.org/PathwayBrowser/#/R-BTA-5649883 POLB-mediated DNA strand displacement synthesis IEA Bos taurus 33019 R-BTA-5655892 https://reactome.org/PathwayBrowser/#/R-BTA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Bos taurus 33019 R-BTA-5655965 https://reactome.org/PathwayBrowser/#/R-BTA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Bos taurus 33019 R-BTA-5656148 https://reactome.org/PathwayBrowser/#/R-BTA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Bos taurus 33019 R-BTA-5656158 https://reactome.org/PathwayBrowser/#/R-BTA-5656158 POLZ elongates POLI-incorporated dNMP IEA Bos taurus 33019 R-BTA-5687360 https://reactome.org/PathwayBrowser/#/R-BTA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Bos taurus 33019 R-BTA-5687640 https://reactome.org/PathwayBrowser/#/R-BTA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Bos taurus 33019 R-BTA-5691001 https://reactome.org/PathwayBrowser/#/R-BTA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Bos taurus 33019 R-BTA-5693593 https://reactome.org/PathwayBrowser/#/R-BTA-5693593 D-loop extension by DNA polymerases IEA Bos taurus 33019 R-BTA-5694494 https://reactome.org/PathwayBrowser/#/R-BTA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Bos taurus 33019 R-BTA-5696004 https://reactome.org/PathwayBrowser/#/R-BTA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Bos taurus 33019 R-BTA-5696007 https://reactome.org/PathwayBrowser/#/R-BTA-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Bos taurus 33019 R-BTA-6781824 https://reactome.org/PathwayBrowser/#/R-BTA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Bos taurus 33019 R-BTA-6782208 https://reactome.org/PathwayBrowser/#/R-BTA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Bos taurus 33019 R-BTA-6786166 https://reactome.org/PathwayBrowser/#/R-BTA-6786166 Translesion synthesis across unhooked ICL by POLN IEA Bos taurus 33019 R-BTA-6787533 https://reactome.org/PathwayBrowser/#/R-BTA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Bos taurus 33019 R-BTA-6788912 https://reactome.org/PathwayBrowser/#/R-BTA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Bos taurus 33019 R-BTA-6806674 https://reactome.org/PathwayBrowser/#/R-BTA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Bos taurus 33019 R-BTA-70286 https://reactome.org/PathwayBrowser/#/R-BTA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Bos taurus 33019 R-BTA-70577 https://reactome.org/PathwayBrowser/#/R-BTA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Bos taurus 33019 R-BTA-70599 https://reactome.org/PathwayBrowser/#/R-BTA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Bos taurus 33019 R-BTA-71732 https://reactome.org/PathwayBrowser/#/R-BTA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Bos taurus 33019 R-BTA-71735 https://reactome.org/PathwayBrowser/#/R-BTA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Bos taurus 33019 R-BTA-73567 https://reactome.org/PathwayBrowser/#/R-BTA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Bos taurus 33019 R-BTA-73666 https://reactome.org/PathwayBrowser/#/R-BTA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Bos taurus 33019 R-BTA-73792 https://reactome.org/PathwayBrowser/#/R-BTA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Bos taurus 33019 R-BTA-73815 https://reactome.org/PathwayBrowser/#/R-BTA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Bos taurus 33019 R-BTA-73932 https://reactome.org/PathwayBrowser/#/R-BTA-73932 Resynthesis of excised residue by POLB IEA Bos taurus 33019 R-BTA-74213 https://reactome.org/PathwayBrowser/#/R-BTA-74213 APRT catalyzes the conversion of adenine to AMP IEA Bos taurus 33019 R-BTA-74215 https://reactome.org/PathwayBrowser/#/R-BTA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Bos taurus 33019 R-BTA-74885 https://reactome.org/PathwayBrowser/#/R-BTA-74885 GUCYs converts GTP to cGMP IEA Bos taurus 33019 R-BTA-75850 https://reactome.org/PathwayBrowser/#/R-BTA-75850 Addition of the third nucleotide on the nascent transcript IEA Bos taurus 33019 R-BTA-75864 https://reactome.org/PathwayBrowser/#/R-BTA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Bos taurus 33019 R-BTA-75869 https://reactome.org/PathwayBrowser/#/R-BTA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Bos taurus 33019 R-BTA-75873 https://reactome.org/PathwayBrowser/#/R-BTA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Bos taurus 33019 R-BTA-76576 https://reactome.org/PathwayBrowser/#/R-BTA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Bos taurus 33019 R-BTA-8852128 https://reactome.org/PathwayBrowser/#/R-BTA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Bos taurus 33019 R-BTA-8852131 https://reactome.org/PathwayBrowser/#/R-BTA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Bos taurus 33019 R-BTA-8852132 https://reactome.org/PathwayBrowser/#/R-BTA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Bos taurus 33019 R-BTA-8852134 https://reactome.org/PathwayBrowser/#/R-BTA-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Bos taurus 33019 R-BTA-8870469 https://reactome.org/PathwayBrowser/#/R-BTA-8870469 RGGT geranylgeranylates RAB proteins IEA Bos taurus 33019 R-BTA-8875071 https://reactome.org/PathwayBrowser/#/R-BTA-8875071 ACSS3 ligates CoA to CH3COO- IEA Bos taurus 33019 R-BTA-8939959 https://reactome.org/PathwayBrowser/#/R-BTA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Bos taurus 33019 R-BTA-8951648 https://reactome.org/PathwayBrowser/#/R-BTA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Bos taurus 33019 R-BTA-8951656 https://reactome.org/PathwayBrowser/#/R-BTA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Bos taurus 33019 R-BTA-9008822 https://reactome.org/PathwayBrowser/#/R-BTA-9008822 PPM1D dephosphorylates RUNX2 IEA Bos taurus 33019 R-BTA-947531 https://reactome.org/PathwayBrowser/#/R-BTA-947531 Molybdenum ion transfer onto molybdopterin IEA Bos taurus 33019 R-BTA-947535 https://reactome.org/PathwayBrowser/#/R-BTA-947535 Cyclisation of GTP to precursor Z IEA Bos taurus 33019 R-BTA-9613494 https://reactome.org/PathwayBrowser/#/R-BTA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Bos taurus 33019 R-BTA-9613497 https://reactome.org/PathwayBrowser/#/R-BTA-9613497 Unwinding DNA for the nascent transcript IEA Bos taurus 33019 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 33019 R-BTA-9717830 https://reactome.org/PathwayBrowser/#/R-BTA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Bos taurus 33019 R-BTA-9717834 https://reactome.org/PathwayBrowser/#/R-BTA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Bos taurus 33019 R-BTA-9731228 https://reactome.org/PathwayBrowser/#/R-BTA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Bos taurus 33019 R-BTA-9731590 https://reactome.org/PathwayBrowser/#/R-BTA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Bos taurus 33019 R-BTA-9731613 https://reactome.org/PathwayBrowser/#/R-BTA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Bos taurus 33019 R-BTA-9731632 https://reactome.org/PathwayBrowser/#/R-BTA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Bos taurus 33019 R-BTA-9734535 https://reactome.org/PathwayBrowser/#/R-BTA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Bos taurus 33019 R-BTA-9748951 https://reactome.org/PathwayBrowser/#/R-BTA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Bos taurus 33019 R-BTA-9748957 https://reactome.org/PathwayBrowser/#/R-BTA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Bos taurus 33019 R-BTA-9749971 https://reactome.org/PathwayBrowser/#/R-BTA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Bos taurus 33019 R-BTA-9750555 https://reactome.org/PathwayBrowser/#/R-BTA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Bos taurus 33019 R-BTA-9755030 https://reactome.org/PathwayBrowser/#/R-BTA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Bos taurus 33019 R-BTA-9760094 https://reactome.org/PathwayBrowser/#/R-BTA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Bos taurus 33019 R-BTA-983140 https://reactome.org/PathwayBrowser/#/R-BTA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Bos taurus 33019 R-BTA-983153 https://reactome.org/PathwayBrowser/#/R-BTA-983153 E1 mediated ubiquitin activation IEA Bos taurus 33019 R-BTA-983156 https://reactome.org/PathwayBrowser/#/R-BTA-983156 Polyubiquitination of substrate IEA Bos taurus 33019 R-BTA-9833973 https://reactome.org/PathwayBrowser/#/R-BTA-9833973 ISGylation of PKR IEA Bos taurus 33019 R-CEL-110317 https://reactome.org/PathwayBrowser/#/R-CEL-110317 Insertion of correct bases opposite the lesion by POLH IEA Caenorhabditis elegans 33019 R-CEL-110319 https://reactome.org/PathwayBrowser/#/R-CEL-110319 Elongation by POLH IEA Caenorhabditis elegans 33019 R-CEL-110368 https://reactome.org/PathwayBrowser/#/R-CEL-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Caenorhabditis elegans 33019 R-CEL-111264 https://reactome.org/PathwayBrowser/#/R-CEL-111264 Addition of nucleotides between position +11 and +30 IEA Caenorhabditis elegans 33019 R-CEL-111930 https://reactome.org/PathwayBrowser/#/R-CEL-111930 Adenylate cyclase produces cAMP IEA Caenorhabditis elegans 33019 R-CEL-1169397 https://reactome.org/PathwayBrowser/#/R-CEL-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Caenorhabditis elegans 33019 R-CEL-1169398 https://reactome.org/PathwayBrowser/#/R-CEL-1169398 ISGylation of host protein filamin B IEA Caenorhabditis elegans 33019 R-CEL-1169402 https://reactome.org/PathwayBrowser/#/R-CEL-1169402 ISGylation of E2 conjugating enzymes IEA Caenorhabditis elegans 33019 R-CEL-1169405 https://reactome.org/PathwayBrowser/#/R-CEL-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Caenorhabditis elegans 33019 R-CEL-1169406 https://reactome.org/PathwayBrowser/#/R-CEL-1169406 ISGylation of host proteins IEA Caenorhabditis elegans 33019 R-CEL-1483081 https://reactome.org/PathwayBrowser/#/R-CEL-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Caenorhabditis elegans 33019 R-CEL-1483121 https://reactome.org/PathwayBrowser/#/R-CEL-1483121 PA is converted to CDP-DAG by CDS1 IEA Caenorhabditis elegans 33019 R-CEL-1483165 https://reactome.org/PathwayBrowser/#/R-CEL-1483165 PA is converted to CDP-DAG by CDS2 IEA Caenorhabditis elegans 33019 R-CEL-1483190 https://reactome.org/PathwayBrowser/#/R-CEL-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Caenorhabditis elegans 33019 R-CEL-159425 https://reactome.org/PathwayBrowser/#/R-CEL-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 33019 R-CEL-170676 https://reactome.org/PathwayBrowser/#/R-CEL-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Caenorhabditis elegans 33019 R-CEL-174392 https://reactome.org/PathwayBrowser/#/R-CEL-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Caenorhabditis elegans 33019 R-CEL-191303 https://reactome.org/PathwayBrowser/#/R-CEL-191303 FDPS dimer transfers IPPP to GPP IEA Caenorhabditis elegans 33019 R-CEL-191322 https://reactome.org/PathwayBrowser/#/R-CEL-191322 FDPS dimer transfers IPPP to DMAPP IEA Caenorhabditis elegans 33019 R-CEL-192137 https://reactome.org/PathwayBrowser/#/R-CEL-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 33019 R-CEL-193401 https://reactome.org/PathwayBrowser/#/R-CEL-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 33019 R-CEL-193407 https://reactome.org/PathwayBrowser/#/R-CEL-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 33019 R-CEL-193424 https://reactome.org/PathwayBrowser/#/R-CEL-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 33019 R-CEL-193711 https://reactome.org/PathwayBrowser/#/R-CEL-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 33019 R-CEL-193727 https://reactome.org/PathwayBrowser/#/R-CEL-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 33019 R-CEL-193743 https://reactome.org/PathwayBrowser/#/R-CEL-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 33019 R-CEL-193766 https://reactome.org/PathwayBrowser/#/R-CEL-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 33019 R-CEL-196753 https://reactome.org/PathwayBrowser/#/R-CEL-196753 2xPPCS ligates PPanK with Cys IEA Caenorhabditis elegans 33019 R-CEL-196754 https://reactome.org/PathwayBrowser/#/R-CEL-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Caenorhabditis elegans 33019 R-CEL-196929 https://reactome.org/PathwayBrowser/#/R-CEL-196929 FLAD1 phosphorylates FMN IEA Caenorhabditis elegans 33019 R-CEL-197186 https://reactome.org/PathwayBrowser/#/R-CEL-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Caenorhabditis elegans 33019 R-CEL-197235 https://reactome.org/PathwayBrowser/#/R-CEL-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 33019 R-CEL-197271 https://reactome.org/PathwayBrowser/#/R-CEL-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Caenorhabditis elegans 33019 R-CEL-200474 https://reactome.org/PathwayBrowser/#/R-CEL-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 33019 R-CEL-200512 https://reactome.org/PathwayBrowser/#/R-CEL-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 33019 R-CEL-201035 https://reactome.org/PathwayBrowser/#/R-CEL-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Caenorhabditis elegans 33019 R-CEL-2162192 https://reactome.org/PathwayBrowser/#/R-CEL-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Caenorhabditis elegans 33019 R-CEL-2509827 https://reactome.org/PathwayBrowser/#/R-CEL-2509827 ITPA hydrolyses ITP to IMP IEA Caenorhabditis elegans 33019 R-CEL-2509831 https://reactome.org/PathwayBrowser/#/R-CEL-2509831 ITPA hydrolyses XTP to XMP IEA Caenorhabditis elegans 33019 R-CEL-2509838 https://reactome.org/PathwayBrowser/#/R-CEL-2509838 ITPA hydrolyses dITP to dIMP IEA Caenorhabditis elegans 33019 R-CEL-2530501 https://reactome.org/PathwayBrowser/#/R-CEL-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Caenorhabditis elegans 33019 R-CEL-2990833 https://reactome.org/PathwayBrowser/#/R-CEL-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Caenorhabditis elegans 33019 R-CEL-2993447 https://reactome.org/PathwayBrowser/#/R-CEL-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Caenorhabditis elegans 33019 R-CEL-2993799 https://reactome.org/PathwayBrowser/#/R-CEL-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Caenorhabditis elegans 33019 R-CEL-2993802 https://reactome.org/PathwayBrowser/#/R-CEL-2993802 HLCS biotinylates PC:Mn2+ IEA Caenorhabditis elegans 33019 R-CEL-2993814 https://reactome.org/PathwayBrowser/#/R-CEL-2993814 HLCS biotinylates ACACA:Mn2+ IEA Caenorhabditis elegans 33019 R-CEL-2995330 https://reactome.org/PathwayBrowser/#/R-CEL-2995330 COX10 transforms heme to heme O IEA Caenorhabditis elegans 33019 R-CEL-389622 https://reactome.org/PathwayBrowser/#/R-CEL-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 33019 R-CEL-389632 https://reactome.org/PathwayBrowser/#/R-CEL-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 33019 R-CEL-392513 https://reactome.org/PathwayBrowser/#/R-CEL-392513 Rap1 signal termination by Rap1GAPs IEA Caenorhabditis elegans 33019 R-CEL-4167511 https://reactome.org/PathwayBrowser/#/R-CEL-4167511 HLCS biotinylates ACACB IEA Caenorhabditis elegans 33019 R-CEL-434382 https://reactome.org/PathwayBrowser/#/R-CEL-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Caenorhabditis elegans 33019 R-CEL-446204 https://reactome.org/PathwayBrowser/#/R-CEL-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Caenorhabditis elegans 33019 R-CEL-449937 https://reactome.org/PathwayBrowser/#/R-CEL-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Caenorhabditis elegans 33019 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 33019 R-CEL-5358475 https://reactome.org/PathwayBrowser/#/R-CEL-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Caenorhabditis elegans 33019 R-CEL-5358592 https://reactome.org/PathwayBrowser/#/R-CEL-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Caenorhabditis elegans 33019 R-CEL-548843 https://reactome.org/PathwayBrowser/#/R-CEL-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Caenorhabditis elegans 33019 R-CEL-5610727 https://reactome.org/PathwayBrowser/#/R-CEL-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Caenorhabditis elegans 33019 R-CEL-5655892 https://reactome.org/PathwayBrowser/#/R-CEL-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Caenorhabditis elegans 33019 R-CEL-5656148 https://reactome.org/PathwayBrowser/#/R-CEL-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Caenorhabditis elegans 33019 R-CEL-5691001 https://reactome.org/PathwayBrowser/#/R-CEL-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Caenorhabditis elegans 33019 R-CEL-5694494 https://reactome.org/PathwayBrowser/#/R-CEL-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Caenorhabditis elegans 33019 R-CEL-5696004 https://reactome.org/PathwayBrowser/#/R-CEL-5696004 ACSF2 ligates CoA-SH to MCFA IEA Caenorhabditis elegans 33019 R-CEL-6781824 https://reactome.org/PathwayBrowser/#/R-CEL-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Caenorhabditis elegans 33019 R-CEL-6782208 https://reactome.org/PathwayBrowser/#/R-CEL-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Caenorhabditis elegans 33019 R-CEL-6787533 https://reactome.org/PathwayBrowser/#/R-CEL-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Caenorhabditis elegans 33019 R-CEL-6788912 https://reactome.org/PathwayBrowser/#/R-CEL-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Caenorhabditis elegans 33019 R-CEL-70286 https://reactome.org/PathwayBrowser/#/R-CEL-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Caenorhabditis elegans 33019 R-CEL-70599 https://reactome.org/PathwayBrowser/#/R-CEL-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Caenorhabditis elegans 33019 R-CEL-71732 https://reactome.org/PathwayBrowser/#/R-CEL-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Caenorhabditis elegans 33019 R-CEL-71735 https://reactome.org/PathwayBrowser/#/R-CEL-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Caenorhabditis elegans 33019 R-CEL-73567 https://reactome.org/PathwayBrowser/#/R-CEL-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Caenorhabditis elegans 33019 R-CEL-73666 https://reactome.org/PathwayBrowser/#/R-CEL-73666 dUTP + H2O => dUMP + pyrophosphate IEA Caenorhabditis elegans 33019 R-CEL-73792 https://reactome.org/PathwayBrowser/#/R-CEL-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Caenorhabditis elegans 33019 R-CEL-73815 https://reactome.org/PathwayBrowser/#/R-CEL-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Caenorhabditis elegans 33019 R-CEL-74213 https://reactome.org/PathwayBrowser/#/R-CEL-74213 APRT catalyzes the conversion of adenine to AMP IEA Caenorhabditis elegans 33019 R-CEL-74215 https://reactome.org/PathwayBrowser/#/R-CEL-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Caenorhabditis elegans 33019 R-CEL-74885 https://reactome.org/PathwayBrowser/#/R-CEL-74885 GUCYs converts GTP to cGMP IEA Caenorhabditis elegans 33019 R-CEL-75850 https://reactome.org/PathwayBrowser/#/R-CEL-75850 Addition of the third nucleotide on the nascent transcript IEA Caenorhabditis elegans 33019 R-CEL-75864 https://reactome.org/PathwayBrowser/#/R-CEL-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Caenorhabditis elegans 33019 R-CEL-75869 https://reactome.org/PathwayBrowser/#/R-CEL-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Caenorhabditis elegans 33019 R-CEL-75873 https://reactome.org/PathwayBrowser/#/R-CEL-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Caenorhabditis elegans 33019 R-CEL-76576 https://reactome.org/PathwayBrowser/#/R-CEL-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Caenorhabditis elegans 33019 R-CEL-8852128 https://reactome.org/PathwayBrowser/#/R-CEL-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Caenorhabditis elegans 33019 R-CEL-8852131 https://reactome.org/PathwayBrowser/#/R-CEL-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Caenorhabditis elegans 33019 R-CEL-8852132 https://reactome.org/PathwayBrowser/#/R-CEL-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Caenorhabditis elegans 33019 R-CEL-8852134 https://reactome.org/PathwayBrowser/#/R-CEL-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Caenorhabditis elegans 33019 R-CEL-8870469 https://reactome.org/PathwayBrowser/#/R-CEL-8870469 RGGT geranylgeranylates RAB proteins IEA Caenorhabditis elegans 33019 R-CEL-8939959 https://reactome.org/PathwayBrowser/#/R-CEL-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Caenorhabditis elegans 33019 R-CEL-8951648 https://reactome.org/PathwayBrowser/#/R-CEL-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Caenorhabditis elegans 33019 R-CEL-8951656 https://reactome.org/PathwayBrowser/#/R-CEL-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Caenorhabditis elegans 33019 R-CEL-9008822 https://reactome.org/PathwayBrowser/#/R-CEL-9008822 PPM1D dephosphorylates RUNX2 IEA Caenorhabditis elegans 33019 R-CEL-947531 https://reactome.org/PathwayBrowser/#/R-CEL-947531 Molybdenum ion transfer onto molybdopterin IEA Caenorhabditis elegans 33019 R-CEL-947535 https://reactome.org/PathwayBrowser/#/R-CEL-947535 Cyclisation of GTP to precursor Z IEA Caenorhabditis elegans 33019 R-CEL-9613494 https://reactome.org/PathwayBrowser/#/R-CEL-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Caenorhabditis elegans 33019 R-CEL-9613497 https://reactome.org/PathwayBrowser/#/R-CEL-9613497 Unwinding DNA for the nascent transcript IEA Caenorhabditis elegans 33019 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 33019 R-CEL-9734535 https://reactome.org/PathwayBrowser/#/R-CEL-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Caenorhabditis elegans 33019 R-CEL-9748951 https://reactome.org/PathwayBrowser/#/R-CEL-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Caenorhabditis elegans 33019 R-CEL-9748957 https://reactome.org/PathwayBrowser/#/R-CEL-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Caenorhabditis elegans 33019 R-CEL-9755030 https://reactome.org/PathwayBrowser/#/R-CEL-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Caenorhabditis elegans 33019 R-CEL-983140 https://reactome.org/PathwayBrowser/#/R-CEL-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Caenorhabditis elegans 33019 R-CEL-983153 https://reactome.org/PathwayBrowser/#/R-CEL-983153 E1 mediated ubiquitin activation IEA Caenorhabditis elegans 33019 R-CEL-983156 https://reactome.org/PathwayBrowser/#/R-CEL-983156 Polyubiquitination of substrate IEA Caenorhabditis elegans 33019 R-CEL-9833973 https://reactome.org/PathwayBrowser/#/R-CEL-9833973 ISGylation of PKR IEA Caenorhabditis elegans 33019 R-CFA-110311 https://reactome.org/PathwayBrowser/#/R-CFA-110311 POLZ extends translesion synthesis IEA Canis familiaris 33019 R-CFA-110317 https://reactome.org/PathwayBrowser/#/R-CFA-110317 Insertion of correct bases opposite the lesion by POLH IEA Canis familiaris 33019 R-CFA-110319 https://reactome.org/PathwayBrowser/#/R-CFA-110319 Elongation by POLH IEA Canis familiaris 33019 R-CFA-110368 https://reactome.org/PathwayBrowser/#/R-CFA-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Canis familiaris 33019 R-CFA-111253 https://reactome.org/PathwayBrowser/#/R-CFA-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Canis familiaris 33019 R-CFA-111264 https://reactome.org/PathwayBrowser/#/R-CFA-111264 Addition of nucleotides between position +11 and +30 IEA Canis familiaris 33019 R-CFA-111930 https://reactome.org/PathwayBrowser/#/R-CFA-111930 Adenylate cyclase produces cAMP IEA Canis familiaris 33019 R-CFA-1169397 https://reactome.org/PathwayBrowser/#/R-CFA-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Canis familiaris 33019 R-CFA-1483081 https://reactome.org/PathwayBrowser/#/R-CFA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Canis familiaris 33019 R-CFA-1483121 https://reactome.org/PathwayBrowser/#/R-CFA-1483121 PA is converted to CDP-DAG by CDS1 IEA Canis familiaris 33019 R-CFA-1483165 https://reactome.org/PathwayBrowser/#/R-CFA-1483165 PA is converted to CDP-DAG by CDS2 IEA Canis familiaris 33019 R-CFA-1483190 https://reactome.org/PathwayBrowser/#/R-CFA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Canis familiaris 33019 R-CFA-159425 https://reactome.org/PathwayBrowser/#/R-CFA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 33019 R-CFA-159443 https://reactome.org/PathwayBrowser/#/R-CFA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 33019 R-CFA-159567 https://reactome.org/PathwayBrowser/#/R-CFA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Canis familiaris 33019 R-CFA-170676 https://reactome.org/PathwayBrowser/#/R-CFA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Canis familiaris 33019 R-CFA-174124 https://reactome.org/PathwayBrowser/#/R-CFA-174124 Dephosphorylation of phospho-Cdh1 IEA Canis familiaris 33019 R-CFA-174391 https://reactome.org/PathwayBrowser/#/R-CFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Canis familiaris 33019 R-CFA-174392 https://reactome.org/PathwayBrowser/#/R-CFA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Canis familiaris 33019 R-CFA-177157 https://reactome.org/PathwayBrowser/#/R-CFA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Canis familiaris 33019 R-CFA-191303 https://reactome.org/PathwayBrowser/#/R-CFA-191303 FDPS dimer transfers IPPP to GPP IEA Canis familiaris 33019 R-CFA-191322 https://reactome.org/PathwayBrowser/#/R-CFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Canis familiaris 33019 R-CFA-191402 https://reactome.org/PathwayBrowser/#/R-CFA-191402 Reduction of presqualene diphosphate to form squalene IEA Canis familiaris 33019 R-CFA-191405 https://reactome.org/PathwayBrowser/#/R-CFA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Canis familiaris 33019 R-CFA-192137 https://reactome.org/PathwayBrowser/#/R-CFA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 33019 R-CFA-193401 https://reactome.org/PathwayBrowser/#/R-CFA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 33019 R-CFA-193407 https://reactome.org/PathwayBrowser/#/R-CFA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 33019 R-CFA-193424 https://reactome.org/PathwayBrowser/#/R-CFA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 33019 R-CFA-193711 https://reactome.org/PathwayBrowser/#/R-CFA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 33019 R-CFA-193727 https://reactome.org/PathwayBrowser/#/R-CFA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 33019 R-CFA-193743 https://reactome.org/PathwayBrowser/#/R-CFA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 33019 R-CFA-193766 https://reactome.org/PathwayBrowser/#/R-CFA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 33019 R-CFA-196753 https://reactome.org/PathwayBrowser/#/R-CFA-196753 2xPPCS ligates PPanK with Cys IEA Canis familiaris 33019 R-CFA-196754 https://reactome.org/PathwayBrowser/#/R-CFA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Canis familiaris 33019 R-CFA-196929 https://reactome.org/PathwayBrowser/#/R-CFA-196929 FLAD1 phosphorylates FMN IEA Canis familiaris 33019 R-CFA-197186 https://reactome.org/PathwayBrowser/#/R-CFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Canis familiaris 33019 R-CFA-197235 https://reactome.org/PathwayBrowser/#/R-CFA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 33019 R-CFA-197250 https://reactome.org/PathwayBrowser/#/R-CFA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Canis familiaris 33019 R-CFA-197268 https://reactome.org/PathwayBrowser/#/R-CFA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Canis familiaris 33019 R-CFA-197271 https://reactome.org/PathwayBrowser/#/R-CFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Canis familiaris 33019 R-CFA-200474 https://reactome.org/PathwayBrowser/#/R-CFA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 33019 R-CFA-200512 https://reactome.org/PathwayBrowser/#/R-CFA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 33019 R-CFA-201035 https://reactome.org/PathwayBrowser/#/R-CFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Canis familiaris 33019 R-CFA-2046085 https://reactome.org/PathwayBrowser/#/R-CFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Canis familiaris 33019 R-CFA-2046098 https://reactome.org/PathwayBrowser/#/R-CFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Canis familiaris 33019 R-CFA-2162192 https://reactome.org/PathwayBrowser/#/R-CFA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Canis familiaris 33019 R-CFA-2162253 https://reactome.org/PathwayBrowser/#/R-CFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Canis familiaris 33019 R-CFA-2395818 https://reactome.org/PathwayBrowser/#/R-CFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Canis familiaris 33019 R-CFA-2395849 https://reactome.org/PathwayBrowser/#/R-CFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 33019 R-CFA-2395869 https://reactome.org/PathwayBrowser/#/R-CFA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 33019 R-CFA-2395872 https://reactome.org/PathwayBrowser/#/R-CFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Canis familiaris 33019 R-CFA-2408551 https://reactome.org/PathwayBrowser/#/R-CFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Canis familiaris 33019 R-CFA-2509827 https://reactome.org/PathwayBrowser/#/R-CFA-2509827 ITPA hydrolyses ITP to IMP IEA Canis familiaris 33019 R-CFA-2509831 https://reactome.org/PathwayBrowser/#/R-CFA-2509831 ITPA hydrolyses XTP to XMP IEA Canis familiaris 33019 R-CFA-2509838 https://reactome.org/PathwayBrowser/#/R-CFA-2509838 ITPA hydrolyses dITP to dIMP IEA Canis familiaris 33019 R-CFA-2730904 https://reactome.org/PathwayBrowser/#/R-CFA-2730904 Auto-ubiquitination of TRAF6 IEA Canis familiaris 33019 R-CFA-2990833 https://reactome.org/PathwayBrowser/#/R-CFA-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Canis familiaris 33019 R-CFA-2993447 https://reactome.org/PathwayBrowser/#/R-CFA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Canis familiaris 33019 R-CFA-2993799 https://reactome.org/PathwayBrowser/#/R-CFA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Canis familiaris 33019 R-CFA-2993802 https://reactome.org/PathwayBrowser/#/R-CFA-2993802 HLCS biotinylates PC:Mn2+ IEA Canis familiaris 33019 R-CFA-2993814 https://reactome.org/PathwayBrowser/#/R-CFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Canis familiaris 33019 R-CFA-2995330 https://reactome.org/PathwayBrowser/#/R-CFA-2995330 COX10 transforms heme to heme O IEA Canis familiaris 33019 R-CFA-389622 https://reactome.org/PathwayBrowser/#/R-CFA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 33019 R-CFA-389632 https://reactome.org/PathwayBrowser/#/R-CFA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 33019 R-CFA-389758 https://reactome.org/PathwayBrowser/#/R-CFA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Canis familiaris 33019 R-CFA-392513 https://reactome.org/PathwayBrowser/#/R-CFA-392513 Rap1 signal termination by Rap1GAPs IEA Canis familiaris 33019 R-CFA-4084982 https://reactome.org/PathwayBrowser/#/R-CFA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Canis familiaris 33019 R-CFA-4167511 https://reactome.org/PathwayBrowser/#/R-CFA-4167511 HLCS biotinylates ACACB IEA Canis familiaris 33019 R-CFA-421879 https://reactome.org/PathwayBrowser/#/R-CFA-421879 Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate TAS Canis familiaris 33019 R-CFA-434382 https://reactome.org/PathwayBrowser/#/R-CFA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Canis familiaris 33019 R-CFA-446204 https://reactome.org/PathwayBrowser/#/R-CFA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Canis familiaris 33019 R-CFA-449911 https://reactome.org/PathwayBrowser/#/R-CFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Canis familiaris 33019 R-CFA-449937 https://reactome.org/PathwayBrowser/#/R-CFA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Canis familiaris 33019 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 33019 R-CFA-5226964 https://reactome.org/PathwayBrowser/#/R-CFA-5226964 ANKH transports PPi from cytosol to extracellular region IEA Canis familiaris 33019 R-CFA-5358475 https://reactome.org/PathwayBrowser/#/R-CFA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Canis familiaris 33019 R-CFA-5358592 https://reactome.org/PathwayBrowser/#/R-CFA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Canis familiaris 33019 R-CFA-548843 https://reactome.org/PathwayBrowser/#/R-CFA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Canis familiaris 33019 R-CFA-5603114 https://reactome.org/PathwayBrowser/#/R-CFA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Canis familiaris 33019 R-CFA-5607756 https://reactome.org/PathwayBrowser/#/R-CFA-5607756 TRAF6 oligomer autoubiquitinates IEA Canis familiaris 33019 R-CFA-5607757 https://reactome.org/PathwayBrowser/#/R-CFA-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 IEA Canis familiaris 33019 R-CFA-5610727 https://reactome.org/PathwayBrowser/#/R-CFA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Canis familiaris 33019 R-CFA-5649723 https://reactome.org/PathwayBrowser/#/R-CFA-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Canis familiaris 33019 R-CFA-5649883 https://reactome.org/PathwayBrowser/#/R-CFA-5649883 POLB-mediated DNA strand displacement synthesis IEA Canis familiaris 33019 R-CFA-5655892 https://reactome.org/PathwayBrowser/#/R-CFA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Canis familiaris 33019 R-CFA-5655965 https://reactome.org/PathwayBrowser/#/R-CFA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Canis familiaris 33019 R-CFA-5656148 https://reactome.org/PathwayBrowser/#/R-CFA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Canis familiaris 33019 R-CFA-5656158 https://reactome.org/PathwayBrowser/#/R-CFA-5656158 POLZ elongates POLI-incorporated dNMP IEA Canis familiaris 33019 R-CFA-5687360 https://reactome.org/PathwayBrowser/#/R-CFA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Canis familiaris 33019 R-CFA-5687640 https://reactome.org/PathwayBrowser/#/R-CFA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Canis familiaris 33019 R-CFA-5691001 https://reactome.org/PathwayBrowser/#/R-CFA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Canis familiaris 33019 R-CFA-5693593 https://reactome.org/PathwayBrowser/#/R-CFA-5693593 D-loop extension by DNA polymerases IEA Canis familiaris 33019 R-CFA-5695957 https://reactome.org/PathwayBrowser/#/R-CFA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Canis familiaris 33019 R-CFA-5696004 https://reactome.org/PathwayBrowser/#/R-CFA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Canis familiaris 33019 R-CFA-6781824 https://reactome.org/PathwayBrowser/#/R-CFA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Canis familiaris 33019 R-CFA-6782208 https://reactome.org/PathwayBrowser/#/R-CFA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Canis familiaris 33019 R-CFA-6786166 https://reactome.org/PathwayBrowser/#/R-CFA-6786166 Translesion synthesis across unhooked ICL by POLN IEA Canis familiaris 33019 R-CFA-6787533 https://reactome.org/PathwayBrowser/#/R-CFA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Canis familiaris 33019 R-CFA-6788912 https://reactome.org/PathwayBrowser/#/R-CFA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Canis familiaris 33019 R-CFA-6806674 https://reactome.org/PathwayBrowser/#/R-CFA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Canis familiaris 33019 R-CFA-70286 https://reactome.org/PathwayBrowser/#/R-CFA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Canis familiaris 33019 R-CFA-70577 https://reactome.org/PathwayBrowser/#/R-CFA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Canis familiaris 33019 R-CFA-70599 https://reactome.org/PathwayBrowser/#/R-CFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Canis familiaris 33019 R-CFA-71732 https://reactome.org/PathwayBrowser/#/R-CFA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Canis familiaris 33019 R-CFA-71735 https://reactome.org/PathwayBrowser/#/R-CFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Canis familiaris 33019 R-CFA-73567 https://reactome.org/PathwayBrowser/#/R-CFA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Canis familiaris 33019 R-CFA-73666 https://reactome.org/PathwayBrowser/#/R-CFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Canis familiaris 33019 R-CFA-73792 https://reactome.org/PathwayBrowser/#/R-CFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Canis familiaris 33019 R-CFA-73815 https://reactome.org/PathwayBrowser/#/R-CFA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Canis familiaris 33019 R-CFA-73932 https://reactome.org/PathwayBrowser/#/R-CFA-73932 Resynthesis of excised residue by POLB IEA Canis familiaris 33019 R-CFA-74213 https://reactome.org/PathwayBrowser/#/R-CFA-74213 APRT catalyzes the conversion of adenine to AMP IEA Canis familiaris 33019 R-CFA-74215 https://reactome.org/PathwayBrowser/#/R-CFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Canis familiaris 33019 R-CFA-74885 https://reactome.org/PathwayBrowser/#/R-CFA-74885 GUCYs converts GTP to cGMP IEA Canis familiaris 33019 R-CFA-75850 https://reactome.org/PathwayBrowser/#/R-CFA-75850 Addition of the third nucleotide on the nascent transcript IEA Canis familiaris 33019 R-CFA-75864 https://reactome.org/PathwayBrowser/#/R-CFA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Canis familiaris 33019 R-CFA-75869 https://reactome.org/PathwayBrowser/#/R-CFA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Canis familiaris 33019 R-CFA-75873 https://reactome.org/PathwayBrowser/#/R-CFA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Canis familiaris 33019 R-CFA-76576 https://reactome.org/PathwayBrowser/#/R-CFA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Canis familiaris 33019 R-CFA-8852128 https://reactome.org/PathwayBrowser/#/R-CFA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Canis familiaris 33019 R-CFA-8852131 https://reactome.org/PathwayBrowser/#/R-CFA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Canis familiaris 33019 R-CFA-8852132 https://reactome.org/PathwayBrowser/#/R-CFA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Canis familiaris 33019 R-CFA-8852134 https://reactome.org/PathwayBrowser/#/R-CFA-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Canis familiaris 33019 R-CFA-8870469 https://reactome.org/PathwayBrowser/#/R-CFA-8870469 RGGT geranylgeranylates RAB proteins IEA Canis familiaris 33019 R-CFA-8875071 https://reactome.org/PathwayBrowser/#/R-CFA-8875071 ACSS3 ligates CoA to CH3COO- IEA Canis familiaris 33019 R-CFA-8939959 https://reactome.org/PathwayBrowser/#/R-CFA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Canis familiaris 33019 R-CFA-8951648 https://reactome.org/PathwayBrowser/#/R-CFA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Canis familiaris 33019 R-CFA-8951656 https://reactome.org/PathwayBrowser/#/R-CFA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Canis familiaris 33019 R-CFA-9008822 https://reactome.org/PathwayBrowser/#/R-CFA-9008822 PPM1D dephosphorylates RUNX2 IEA Canis familiaris 33019 R-CFA-947531 https://reactome.org/PathwayBrowser/#/R-CFA-947531 Molybdenum ion transfer onto molybdopterin IEA Canis familiaris 33019 R-CFA-947535 https://reactome.org/PathwayBrowser/#/R-CFA-947535 Cyclisation of GTP to precursor Z IEA Canis familiaris 33019 R-CFA-9613494 https://reactome.org/PathwayBrowser/#/R-CFA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Canis familiaris 33019 R-CFA-9613497 https://reactome.org/PathwayBrowser/#/R-CFA-9613497 Unwinding DNA for the nascent transcript IEA Canis familiaris 33019 R-CFA-9717830 https://reactome.org/PathwayBrowser/#/R-CFA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Canis familiaris 33019 R-CFA-9717834 https://reactome.org/PathwayBrowser/#/R-CFA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Canis familiaris 33019 R-CFA-9731228 https://reactome.org/PathwayBrowser/#/R-CFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Canis familiaris 33019 R-CFA-9731590 https://reactome.org/PathwayBrowser/#/R-CFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Canis familiaris 33019 R-CFA-9731613 https://reactome.org/PathwayBrowser/#/R-CFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Canis familiaris 33019 R-CFA-9731632 https://reactome.org/PathwayBrowser/#/R-CFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Canis familiaris 33019 R-CFA-9734535 https://reactome.org/PathwayBrowser/#/R-CFA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Canis familiaris 33019 R-CFA-9748951 https://reactome.org/PathwayBrowser/#/R-CFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Canis familiaris 33019 R-CFA-9748957 https://reactome.org/PathwayBrowser/#/R-CFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Canis familiaris 33019 R-CFA-9749971 https://reactome.org/PathwayBrowser/#/R-CFA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Canis familiaris 33019 R-CFA-9750555 https://reactome.org/PathwayBrowser/#/R-CFA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Canis familiaris 33019 R-CFA-9755030 https://reactome.org/PathwayBrowser/#/R-CFA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Canis familiaris 33019 R-CFA-9760094 https://reactome.org/PathwayBrowser/#/R-CFA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Canis familiaris 33019 R-CFA-983140 https://reactome.org/PathwayBrowser/#/R-CFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Canis familiaris 33019 R-CFA-983153 https://reactome.org/PathwayBrowser/#/R-CFA-983153 E1 mediated ubiquitin activation IEA Canis familiaris 33019 R-CFA-983156 https://reactome.org/PathwayBrowser/#/R-CFA-983156 Polyubiquitination of substrate IEA Canis familiaris 33019 R-DDI-110368 https://reactome.org/PathwayBrowser/#/R-DDI-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Dictyostelium discoideum 33019 R-DDI-111253 https://reactome.org/PathwayBrowser/#/R-DDI-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Dictyostelium discoideum 33019 R-DDI-111264 https://reactome.org/PathwayBrowser/#/R-DDI-111264 Addition of nucleotides between position +11 and +30 IEA Dictyostelium discoideum 33019 R-DDI-111930 https://reactome.org/PathwayBrowser/#/R-DDI-111930 Adenylate cyclase produces cAMP IEA Dictyostelium discoideum 33019 R-DDI-1169397 https://reactome.org/PathwayBrowser/#/R-DDI-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Dictyostelium discoideum 33019 R-DDI-1169398 https://reactome.org/PathwayBrowser/#/R-DDI-1169398 ISGylation of host protein filamin B IEA Dictyostelium discoideum 33019 R-DDI-1169402 https://reactome.org/PathwayBrowser/#/R-DDI-1169402 ISGylation of E2 conjugating enzymes IEA Dictyostelium discoideum 33019 R-DDI-1169406 https://reactome.org/PathwayBrowser/#/R-DDI-1169406 ISGylation of host proteins IEA Dictyostelium discoideum 33019 R-DDI-1483081 https://reactome.org/PathwayBrowser/#/R-DDI-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Dictyostelium discoideum 33019 R-DDI-1483121 https://reactome.org/PathwayBrowser/#/R-DDI-1483121 PA is converted to CDP-DAG by CDS1 IEA Dictyostelium discoideum 33019 R-DDI-1483165 https://reactome.org/PathwayBrowser/#/R-DDI-1483165 PA is converted to CDP-DAG by CDS2 IEA Dictyostelium discoideum 33019 R-DDI-1483190 https://reactome.org/PathwayBrowser/#/R-DDI-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Dictyostelium discoideum 33019 R-DDI-170676 https://reactome.org/PathwayBrowser/#/R-DDI-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Dictyostelium discoideum 33019 R-DDI-174391 https://reactome.org/PathwayBrowser/#/R-DDI-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Dictyostelium discoideum 33019 R-DDI-191303 https://reactome.org/PathwayBrowser/#/R-DDI-191303 FDPS dimer transfers IPPP to GPP IEA Dictyostelium discoideum 33019 R-DDI-191322 https://reactome.org/PathwayBrowser/#/R-DDI-191322 FDPS dimer transfers IPPP to DMAPP IEA Dictyostelium discoideum 33019 R-DDI-191402 https://reactome.org/PathwayBrowser/#/R-DDI-191402 Reduction of presqualene diphosphate to form squalene IEA Dictyostelium discoideum 33019 R-DDI-191405 https://reactome.org/PathwayBrowser/#/R-DDI-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Dictyostelium discoideum 33019 R-DDI-196753 https://reactome.org/PathwayBrowser/#/R-DDI-196753 2xPPCS ligates PPanK with Cys IEA Dictyostelium discoideum 33019 R-DDI-196754 https://reactome.org/PathwayBrowser/#/R-DDI-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Dictyostelium discoideum 33019 R-DDI-196929 https://reactome.org/PathwayBrowser/#/R-DDI-196929 FLAD1 phosphorylates FMN IEA Dictyostelium discoideum 33019 R-DDI-197186 https://reactome.org/PathwayBrowser/#/R-DDI-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Dictyostelium discoideum 33019 R-DDI-197235 https://reactome.org/PathwayBrowser/#/R-DDI-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 33019 R-DDI-197268 https://reactome.org/PathwayBrowser/#/R-DDI-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Dictyostelium discoideum 33019 R-DDI-197271 https://reactome.org/PathwayBrowser/#/R-DDI-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Dictyostelium discoideum 33019 R-DDI-200474 https://reactome.org/PathwayBrowser/#/R-DDI-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 33019 R-DDI-200512 https://reactome.org/PathwayBrowser/#/R-DDI-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 33019 R-DDI-201035 https://reactome.org/PathwayBrowser/#/R-DDI-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Dictyostelium discoideum 33019 R-DDI-2046085 https://reactome.org/PathwayBrowser/#/R-DDI-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Dictyostelium discoideum 33019 R-DDI-2046098 https://reactome.org/PathwayBrowser/#/R-DDI-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Dictyostelium discoideum 33019 R-DDI-2162192 https://reactome.org/PathwayBrowser/#/R-DDI-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Dictyostelium discoideum 33019 R-DDI-2162253 https://reactome.org/PathwayBrowser/#/R-DDI-2162253 PDSS1,2 ligates FPP to IPPP IEA Dictyostelium discoideum 33019 R-DDI-2408551 https://reactome.org/PathwayBrowser/#/R-DDI-2408551 SeMet is converted to AdoSeMet by MAT IEA Dictyostelium discoideum 33019 R-DDI-2509827 https://reactome.org/PathwayBrowser/#/R-DDI-2509827 ITPA hydrolyses ITP to IMP IEA Dictyostelium discoideum 33019 R-DDI-2509831 https://reactome.org/PathwayBrowser/#/R-DDI-2509831 ITPA hydrolyses XTP to XMP IEA Dictyostelium discoideum 33019 R-DDI-2509838 https://reactome.org/PathwayBrowser/#/R-DDI-2509838 ITPA hydrolyses dITP to dIMP IEA Dictyostelium discoideum 33019 R-DDI-2990833 https://reactome.org/PathwayBrowser/#/R-DDI-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Dictyostelium discoideum 33019 R-DDI-2993447 https://reactome.org/PathwayBrowser/#/R-DDI-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Dictyostelium discoideum 33019 R-DDI-2993799 https://reactome.org/PathwayBrowser/#/R-DDI-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Dictyostelium discoideum 33019 R-DDI-2993814 https://reactome.org/PathwayBrowser/#/R-DDI-2993814 HLCS biotinylates ACACA:Mn2+ IEA Dictyostelium discoideum 33019 R-DDI-2995330 https://reactome.org/PathwayBrowser/#/R-DDI-2995330 COX10 transforms heme to heme O IEA Dictyostelium discoideum 33019 R-DDI-392513 https://reactome.org/PathwayBrowser/#/R-DDI-392513 Rap1 signal termination by Rap1GAPs IEA Dictyostelium discoideum 33019 R-DDI-4167511 https://reactome.org/PathwayBrowser/#/R-DDI-4167511 HLCS biotinylates ACACB IEA Dictyostelium discoideum 33019 R-DDI-446204 https://reactome.org/PathwayBrowser/#/R-DDI-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Dictyostelium discoideum 33019 R-DDI-449911 https://reactome.org/PathwayBrowser/#/R-DDI-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Dictyostelium discoideum 33019 R-DDI-449937 https://reactome.org/PathwayBrowser/#/R-DDI-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Dictyostelium discoideum 33019 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 33019 R-DDI-5358475 https://reactome.org/PathwayBrowser/#/R-DDI-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Dictyostelium discoideum 33019 R-DDI-5358592 https://reactome.org/PathwayBrowser/#/R-DDI-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Dictyostelium discoideum 33019 R-DDI-5603114 https://reactome.org/PathwayBrowser/#/R-DDI-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Dictyostelium discoideum 33019 R-DDI-5610727 https://reactome.org/PathwayBrowser/#/R-DDI-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Dictyostelium discoideum 33019 R-DDI-5649723 https://reactome.org/PathwayBrowser/#/R-DDI-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Dictyostelium discoideum 33019 R-DDI-5649883 https://reactome.org/PathwayBrowser/#/R-DDI-5649883 POLB-mediated DNA strand displacement synthesis IEA Dictyostelium discoideum 33019 R-DDI-5655892 https://reactome.org/PathwayBrowser/#/R-DDI-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Dictyostelium discoideum 33019 R-DDI-5687360 https://reactome.org/PathwayBrowser/#/R-DDI-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Dictyostelium discoideum 33019 R-DDI-5691001 https://reactome.org/PathwayBrowser/#/R-DDI-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Dictyostelium discoideum 33019 R-DDI-5695957 https://reactome.org/PathwayBrowser/#/R-DDI-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Dictyostelium discoideum 33019 R-DDI-5696007 https://reactome.org/PathwayBrowser/#/R-DDI-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Dictyostelium discoideum 33019 R-DDI-6781824 https://reactome.org/PathwayBrowser/#/R-DDI-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Dictyostelium discoideum 33019 R-DDI-6782208 https://reactome.org/PathwayBrowser/#/R-DDI-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Dictyostelium discoideum 33019 R-DDI-6787533 https://reactome.org/PathwayBrowser/#/R-DDI-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Dictyostelium discoideum 33019 R-DDI-6806674 https://reactome.org/PathwayBrowser/#/R-DDI-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Dictyostelium discoideum 33019 R-DDI-70286 https://reactome.org/PathwayBrowser/#/R-DDI-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Dictyostelium discoideum 33019 R-DDI-70599 https://reactome.org/PathwayBrowser/#/R-DDI-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Dictyostelium discoideum 33019 R-DDI-71732 https://reactome.org/PathwayBrowser/#/R-DDI-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Dictyostelium discoideum 33019 R-DDI-71735 https://reactome.org/PathwayBrowser/#/R-DDI-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Dictyostelium discoideum 33019 R-DDI-73567 https://reactome.org/PathwayBrowser/#/R-DDI-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Dictyostelium discoideum 33019 R-DDI-73666 https://reactome.org/PathwayBrowser/#/R-DDI-73666 dUTP + H2O => dUMP + pyrophosphate IEA Dictyostelium discoideum 33019 R-DDI-73792 https://reactome.org/PathwayBrowser/#/R-DDI-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Dictyostelium discoideum 33019 R-DDI-73932 https://reactome.org/PathwayBrowser/#/R-DDI-73932 Resynthesis of excised residue by POLB IEA Dictyostelium discoideum 33019 R-DDI-74215 https://reactome.org/PathwayBrowser/#/R-DDI-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Dictyostelium discoideum 33019 R-DDI-74885 https://reactome.org/PathwayBrowser/#/R-DDI-74885 GUCYs converts GTP to cGMP IEA Dictyostelium discoideum 33019 R-DDI-75850 https://reactome.org/PathwayBrowser/#/R-DDI-75850 Addition of the third nucleotide on the nascent transcript IEA Dictyostelium discoideum 33019 R-DDI-75864 https://reactome.org/PathwayBrowser/#/R-DDI-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Dictyostelium discoideum 33019 R-DDI-75869 https://reactome.org/PathwayBrowser/#/R-DDI-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Dictyostelium discoideum 33019 R-DDI-75873 https://reactome.org/PathwayBrowser/#/R-DDI-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Dictyostelium discoideum 33019 R-DDI-76576 https://reactome.org/PathwayBrowser/#/R-DDI-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Dictyostelium discoideum 33019 R-DDI-8852128 https://reactome.org/PathwayBrowser/#/R-DDI-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Dictyostelium discoideum 33019 R-DDI-8852131 https://reactome.org/PathwayBrowser/#/R-DDI-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Dictyostelium discoideum 33019 R-DDI-8852132 https://reactome.org/PathwayBrowser/#/R-DDI-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Dictyostelium discoideum 33019 R-DDI-8852134 https://reactome.org/PathwayBrowser/#/R-DDI-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Dictyostelium discoideum 33019 R-DDI-8870469 https://reactome.org/PathwayBrowser/#/R-DDI-8870469 RGGT geranylgeranylates RAB proteins IEA Dictyostelium discoideum 33019 R-DDI-8875071 https://reactome.org/PathwayBrowser/#/R-DDI-8875071 ACSS3 ligates CoA to CH3COO- IEA Dictyostelium discoideum 33019 R-DDI-8939959 https://reactome.org/PathwayBrowser/#/R-DDI-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Dictyostelium discoideum 33019 R-DDI-8951648 https://reactome.org/PathwayBrowser/#/R-DDI-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Dictyostelium discoideum 33019 R-DDI-8951656 https://reactome.org/PathwayBrowser/#/R-DDI-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Dictyostelium discoideum 33019 R-DDI-947531 https://reactome.org/PathwayBrowser/#/R-DDI-947531 Molybdenum ion transfer onto molybdopterin IEA Dictyostelium discoideum 33019 R-DDI-947535 https://reactome.org/PathwayBrowser/#/R-DDI-947535 Cyclisation of GTP to precursor Z IEA Dictyostelium discoideum 33019 R-DDI-9613494 https://reactome.org/PathwayBrowser/#/R-DDI-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Dictyostelium discoideum 33019 R-DDI-9613497 https://reactome.org/PathwayBrowser/#/R-DDI-9613497 Unwinding DNA for the nascent transcript IEA Dictyostelium discoideum 33019 R-DDI-9717830 https://reactome.org/PathwayBrowser/#/R-DDI-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Dictyostelium discoideum 33019 R-DDI-9717834 https://reactome.org/PathwayBrowser/#/R-DDI-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Dictyostelium discoideum 33019 R-DDI-9748951 https://reactome.org/PathwayBrowser/#/R-DDI-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Dictyostelium discoideum 33019 R-DDI-9748957 https://reactome.org/PathwayBrowser/#/R-DDI-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Dictyostelium discoideum 33019 R-DDI-9755030 https://reactome.org/PathwayBrowser/#/R-DDI-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Dictyostelium discoideum 33019 R-DDI-983140 https://reactome.org/PathwayBrowser/#/R-DDI-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Dictyostelium discoideum 33019 R-DDI-983153 https://reactome.org/PathwayBrowser/#/R-DDI-983153 E1 mediated ubiquitin activation IEA Dictyostelium discoideum 33019 R-DDI-983156 https://reactome.org/PathwayBrowser/#/R-DDI-983156 Polyubiquitination of substrate IEA Dictyostelium discoideum 33019 R-DME-110311 https://reactome.org/PathwayBrowser/#/R-DME-110311 POLZ extends translesion synthesis IEA Drosophila melanogaster 33019 R-DME-110317 https://reactome.org/PathwayBrowser/#/R-DME-110317 Insertion of correct bases opposite the lesion by POLH IEA Drosophila melanogaster 33019 R-DME-110319 https://reactome.org/PathwayBrowser/#/R-DME-110319 Elongation by POLH IEA Drosophila melanogaster 33019 R-DME-110368 https://reactome.org/PathwayBrowser/#/R-DME-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Drosophila melanogaster 33019 R-DME-111264 https://reactome.org/PathwayBrowser/#/R-DME-111264 Addition of nucleotides between position +11 and +30 IEA Drosophila melanogaster 33019 R-DME-111930 https://reactome.org/PathwayBrowser/#/R-DME-111930 Adenylate cyclase produces cAMP IEA Drosophila melanogaster 33019 R-DME-1169397 https://reactome.org/PathwayBrowser/#/R-DME-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Drosophila melanogaster 33019 R-DME-1169398 https://reactome.org/PathwayBrowser/#/R-DME-1169398 ISGylation of host protein filamin B IEA Drosophila melanogaster 33019 R-DME-1169402 https://reactome.org/PathwayBrowser/#/R-DME-1169402 ISGylation of E2 conjugating enzymes IEA Drosophila melanogaster 33019 R-DME-1169405 https://reactome.org/PathwayBrowser/#/R-DME-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Drosophila melanogaster 33019 R-DME-1169406 https://reactome.org/PathwayBrowser/#/R-DME-1169406 ISGylation of host proteins IEA Drosophila melanogaster 33019 R-DME-1483081 https://reactome.org/PathwayBrowser/#/R-DME-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Drosophila melanogaster 33019 R-DME-1483121 https://reactome.org/PathwayBrowser/#/R-DME-1483121 PA is converted to CDP-DAG by CDS1 IEA Drosophila melanogaster 33019 R-DME-1483165 https://reactome.org/PathwayBrowser/#/R-DME-1483165 PA is converted to CDP-DAG by CDS2 IEA Drosophila melanogaster 33019 R-DME-1483190 https://reactome.org/PathwayBrowser/#/R-DME-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Drosophila melanogaster 33019 R-DME-159425 https://reactome.org/PathwayBrowser/#/R-DME-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 33019 R-DME-170676 https://reactome.org/PathwayBrowser/#/R-DME-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Drosophila melanogaster 33019 R-DME-174124 https://reactome.org/PathwayBrowser/#/R-DME-174124 Dephosphorylation of phospho-Cdh1 IEA Drosophila melanogaster 33019 R-DME-174392 https://reactome.org/PathwayBrowser/#/R-DME-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Drosophila melanogaster 33019 R-DME-191303 https://reactome.org/PathwayBrowser/#/R-DME-191303 FDPS dimer transfers IPPP to GPP IEA Drosophila melanogaster 33019 R-DME-191322 https://reactome.org/PathwayBrowser/#/R-DME-191322 FDPS dimer transfers IPPP to DMAPP IEA Drosophila melanogaster 33019 R-DME-192137 https://reactome.org/PathwayBrowser/#/R-DME-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 33019 R-DME-193401 https://reactome.org/PathwayBrowser/#/R-DME-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 33019 R-DME-193407 https://reactome.org/PathwayBrowser/#/R-DME-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 33019 R-DME-193424 https://reactome.org/PathwayBrowser/#/R-DME-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 33019 R-DME-193711 https://reactome.org/PathwayBrowser/#/R-DME-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 33019 R-DME-193727 https://reactome.org/PathwayBrowser/#/R-DME-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 33019 R-DME-193743 https://reactome.org/PathwayBrowser/#/R-DME-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 33019 R-DME-193766 https://reactome.org/PathwayBrowser/#/R-DME-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 33019 R-DME-196753 https://reactome.org/PathwayBrowser/#/R-DME-196753 2xPPCS ligates PPanK with Cys IEA Drosophila melanogaster 33019 R-DME-196929 https://reactome.org/PathwayBrowser/#/R-DME-196929 FLAD1 phosphorylates FMN IEA Drosophila melanogaster 33019 R-DME-197186 https://reactome.org/PathwayBrowser/#/R-DME-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Drosophila melanogaster 33019 R-DME-197235 https://reactome.org/PathwayBrowser/#/R-DME-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 33019 R-DME-197271 https://reactome.org/PathwayBrowser/#/R-DME-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Drosophila melanogaster 33019 R-DME-200474 https://reactome.org/PathwayBrowser/#/R-DME-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 33019 R-DME-200512 https://reactome.org/PathwayBrowser/#/R-DME-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 33019 R-DME-201035 https://reactome.org/PathwayBrowser/#/R-DME-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Drosophila melanogaster 33019 R-DME-2162192 https://reactome.org/PathwayBrowser/#/R-DME-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Drosophila melanogaster 33019 R-DME-2162253 https://reactome.org/PathwayBrowser/#/R-DME-2162253 PDSS1,2 ligates FPP to IPPP IEA Drosophila melanogaster 33019 R-DME-2509827 https://reactome.org/PathwayBrowser/#/R-DME-2509827 ITPA hydrolyses ITP to IMP IEA Drosophila melanogaster 33019 R-DME-2509831 https://reactome.org/PathwayBrowser/#/R-DME-2509831 ITPA hydrolyses XTP to XMP IEA Drosophila melanogaster 33019 R-DME-2509838 https://reactome.org/PathwayBrowser/#/R-DME-2509838 ITPA hydrolyses dITP to dIMP IEA Drosophila melanogaster 33019 R-DME-2530501 https://reactome.org/PathwayBrowser/#/R-DME-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Drosophila melanogaster 33019 R-DME-2993799 https://reactome.org/PathwayBrowser/#/R-DME-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Drosophila melanogaster 33019 R-DME-2993802 https://reactome.org/PathwayBrowser/#/R-DME-2993802 HLCS biotinylates PC:Mn2+ IEA Drosophila melanogaster 33019 R-DME-2993814 https://reactome.org/PathwayBrowser/#/R-DME-2993814 HLCS biotinylates ACACA:Mn2+ IEA Drosophila melanogaster 33019 R-DME-2995330 https://reactome.org/PathwayBrowser/#/R-DME-2995330 COX10 transforms heme to heme O IEA Drosophila melanogaster 33019 R-DME-389622 https://reactome.org/PathwayBrowser/#/R-DME-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 33019 R-DME-389632 https://reactome.org/PathwayBrowser/#/R-DME-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 33019 R-DME-392513 https://reactome.org/PathwayBrowser/#/R-DME-392513 Rap1 signal termination by Rap1GAPs IEA Drosophila melanogaster 33019 R-DME-4167511 https://reactome.org/PathwayBrowser/#/R-DME-4167511 HLCS biotinylates ACACB IEA Drosophila melanogaster 33019 R-DME-434382 https://reactome.org/PathwayBrowser/#/R-DME-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Drosophila melanogaster 33019 R-DME-446204 https://reactome.org/PathwayBrowser/#/R-DME-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Drosophila melanogaster 33019 R-DME-449937 https://reactome.org/PathwayBrowser/#/R-DME-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Drosophila melanogaster 33019 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 33019 R-DME-5358475 https://reactome.org/PathwayBrowser/#/R-DME-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Drosophila melanogaster 33019 R-DME-5358592 https://reactome.org/PathwayBrowser/#/R-DME-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Drosophila melanogaster 33019 R-DME-548843 https://reactome.org/PathwayBrowser/#/R-DME-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Drosophila melanogaster 33019 R-DME-5610727 https://reactome.org/PathwayBrowser/#/R-DME-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Drosophila melanogaster 33019 R-DME-5655892 https://reactome.org/PathwayBrowser/#/R-DME-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Drosophila melanogaster 33019 R-DME-5655965 https://reactome.org/PathwayBrowser/#/R-DME-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Drosophila melanogaster 33019 R-DME-5656148 https://reactome.org/PathwayBrowser/#/R-DME-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Drosophila melanogaster 33019 R-DME-5656158 https://reactome.org/PathwayBrowser/#/R-DME-5656158 POLZ elongates POLI-incorporated dNMP IEA Drosophila melanogaster 33019 R-DME-5687640 https://reactome.org/PathwayBrowser/#/R-DME-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Drosophila melanogaster 33019 R-DME-5691001 https://reactome.org/PathwayBrowser/#/R-DME-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Drosophila melanogaster 33019 R-DME-5695957 https://reactome.org/PathwayBrowser/#/R-DME-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Drosophila melanogaster 33019 R-DME-5696004 https://reactome.org/PathwayBrowser/#/R-DME-5696004 ACSF2 ligates CoA-SH to MCFA IEA Drosophila melanogaster 33019 R-DME-5696007 https://reactome.org/PathwayBrowser/#/R-DME-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Drosophila melanogaster 33019 R-DME-6781824 https://reactome.org/PathwayBrowser/#/R-DME-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Drosophila melanogaster 33019 R-DME-6782208 https://reactome.org/PathwayBrowser/#/R-DME-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Drosophila melanogaster 33019 R-DME-6806674 https://reactome.org/PathwayBrowser/#/R-DME-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 33019 R-DME-70286 https://reactome.org/PathwayBrowser/#/R-DME-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Drosophila melanogaster 33019 R-DME-71732 https://reactome.org/PathwayBrowser/#/R-DME-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Drosophila melanogaster 33019 R-DME-71735 https://reactome.org/PathwayBrowser/#/R-DME-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Drosophila melanogaster 33019 R-DME-73567 https://reactome.org/PathwayBrowser/#/R-DME-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Drosophila melanogaster 33019 R-DME-73666 https://reactome.org/PathwayBrowser/#/R-DME-73666 dUTP + H2O => dUMP + pyrophosphate IEA Drosophila melanogaster 33019 R-DME-73792 https://reactome.org/PathwayBrowser/#/R-DME-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Drosophila melanogaster 33019 R-DME-73815 https://reactome.org/PathwayBrowser/#/R-DME-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Drosophila melanogaster 33019 R-DME-74213 https://reactome.org/PathwayBrowser/#/R-DME-74213 APRT catalyzes the conversion of adenine to AMP IEA Drosophila melanogaster 33019 R-DME-74885 https://reactome.org/PathwayBrowser/#/R-DME-74885 GUCYs converts GTP to cGMP IEA Drosophila melanogaster 33019 R-DME-75850 https://reactome.org/PathwayBrowser/#/R-DME-75850 Addition of the third nucleotide on the nascent transcript IEA Drosophila melanogaster 33019 R-DME-75864 https://reactome.org/PathwayBrowser/#/R-DME-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Drosophila melanogaster 33019 R-DME-75869 https://reactome.org/PathwayBrowser/#/R-DME-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Drosophila melanogaster 33019 R-DME-75873 https://reactome.org/PathwayBrowser/#/R-DME-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Drosophila melanogaster 33019 R-DME-76576 https://reactome.org/PathwayBrowser/#/R-DME-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Drosophila melanogaster 33019 R-DME-8852128 https://reactome.org/PathwayBrowser/#/R-DME-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Drosophila melanogaster 33019 R-DME-8852131 https://reactome.org/PathwayBrowser/#/R-DME-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Drosophila melanogaster 33019 R-DME-8852132 https://reactome.org/PathwayBrowser/#/R-DME-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Drosophila melanogaster 33019 R-DME-8852134 https://reactome.org/PathwayBrowser/#/R-DME-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Drosophila melanogaster 33019 R-DME-8870469 https://reactome.org/PathwayBrowser/#/R-DME-8870469 RGGT geranylgeranylates RAB proteins IEA Drosophila melanogaster 33019 R-DME-8875071 https://reactome.org/PathwayBrowser/#/R-DME-8875071 ACSS3 ligates CoA to CH3COO- IEA Drosophila melanogaster 33019 R-DME-8939959 https://reactome.org/PathwayBrowser/#/R-DME-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Drosophila melanogaster 33019 R-DME-8951648 https://reactome.org/PathwayBrowser/#/R-DME-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Drosophila melanogaster 33019 R-DME-8951656 https://reactome.org/PathwayBrowser/#/R-DME-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Drosophila melanogaster 33019 R-DME-9008822 https://reactome.org/PathwayBrowser/#/R-DME-9008822 PPM1D dephosphorylates RUNX2 IEA Drosophila melanogaster 33019 R-DME-947531 https://reactome.org/PathwayBrowser/#/R-DME-947531 Molybdenum ion transfer onto molybdopterin IEA Drosophila melanogaster 33019 R-DME-947535 https://reactome.org/PathwayBrowser/#/R-DME-947535 Cyclisation of GTP to precursor Z IEA Drosophila melanogaster 33019 R-DME-9613494 https://reactome.org/PathwayBrowser/#/R-DME-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Drosophila melanogaster 33019 R-DME-9613497 https://reactome.org/PathwayBrowser/#/R-DME-9613497 Unwinding DNA for the nascent transcript IEA Drosophila melanogaster 33019 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 33019 R-DME-9717830 https://reactome.org/PathwayBrowser/#/R-DME-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Drosophila melanogaster 33019 R-DME-9717834 https://reactome.org/PathwayBrowser/#/R-DME-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Drosophila melanogaster 33019 R-DME-9734535 https://reactome.org/PathwayBrowser/#/R-DME-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Drosophila melanogaster 33019 R-DME-9748957 https://reactome.org/PathwayBrowser/#/R-DME-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Drosophila melanogaster 33019 R-DME-9755030 https://reactome.org/PathwayBrowser/#/R-DME-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Drosophila melanogaster 33019 R-DME-9760094 https://reactome.org/PathwayBrowser/#/R-DME-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Drosophila melanogaster 33019 R-DME-983140 https://reactome.org/PathwayBrowser/#/R-DME-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Drosophila melanogaster 33019 R-DME-983153 https://reactome.org/PathwayBrowser/#/R-DME-983153 E1 mediated ubiquitin activation IEA Drosophila melanogaster 33019 R-DME-983156 https://reactome.org/PathwayBrowser/#/R-DME-983156 Polyubiquitination of substrate IEA Drosophila melanogaster 33019 R-DME-9833973 https://reactome.org/PathwayBrowser/#/R-DME-9833973 ISGylation of PKR IEA Drosophila melanogaster 33019 R-DRE-110317 https://reactome.org/PathwayBrowser/#/R-DRE-110317 Insertion of correct bases opposite the lesion by POLH IEA Danio rerio 33019 R-DRE-110319 https://reactome.org/PathwayBrowser/#/R-DRE-110319 Elongation by POLH IEA Danio rerio 33019 R-DRE-111253 https://reactome.org/PathwayBrowser/#/R-DRE-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Danio rerio 33019 R-DRE-111930 https://reactome.org/PathwayBrowser/#/R-DRE-111930 Adenylate cyclase produces cAMP IEA Danio rerio 33019 R-DRE-1483081 https://reactome.org/PathwayBrowser/#/R-DRE-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Danio rerio 33019 R-DRE-1483165 https://reactome.org/PathwayBrowser/#/R-DRE-1483165 PA is converted to CDP-DAG by CDS2 IEA Danio rerio 33019 R-DRE-1483190 https://reactome.org/PathwayBrowser/#/R-DRE-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Danio rerio 33019 R-DRE-159425 https://reactome.org/PathwayBrowser/#/R-DRE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 33019 R-DRE-159443 https://reactome.org/PathwayBrowser/#/R-DRE-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Danio rerio 33019 R-DRE-159567 https://reactome.org/PathwayBrowser/#/R-DRE-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Danio rerio 33019 R-DRE-170676 https://reactome.org/PathwayBrowser/#/R-DRE-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Danio rerio 33019 R-DRE-174124 https://reactome.org/PathwayBrowser/#/R-DRE-174124 Dephosphorylation of phospho-Cdh1 IEA Danio rerio 33019 R-DRE-174391 https://reactome.org/PathwayBrowser/#/R-DRE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Danio rerio 33019 R-DRE-174392 https://reactome.org/PathwayBrowser/#/R-DRE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Danio rerio 33019 R-DRE-177157 https://reactome.org/PathwayBrowser/#/R-DRE-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Danio rerio 33019 R-DRE-191303 https://reactome.org/PathwayBrowser/#/R-DRE-191303 FDPS dimer transfers IPPP to GPP IEA Danio rerio 33019 R-DRE-191322 https://reactome.org/PathwayBrowser/#/R-DRE-191322 FDPS dimer transfers IPPP to DMAPP IEA Danio rerio 33019 R-DRE-192137 https://reactome.org/PathwayBrowser/#/R-DRE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 33019 R-DRE-193407 https://reactome.org/PathwayBrowser/#/R-DRE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 33019 R-DRE-193711 https://reactome.org/PathwayBrowser/#/R-DRE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 33019 R-DRE-193766 https://reactome.org/PathwayBrowser/#/R-DRE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 33019 R-DRE-196753 https://reactome.org/PathwayBrowser/#/R-DRE-196753 2xPPCS ligates PPanK with Cys IEA Danio rerio 33019 R-DRE-196754 https://reactome.org/PathwayBrowser/#/R-DRE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Danio rerio 33019 R-DRE-196929 https://reactome.org/PathwayBrowser/#/R-DRE-196929 FLAD1 phosphorylates FMN IEA Danio rerio 33019 R-DRE-197186 https://reactome.org/PathwayBrowser/#/R-DRE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Danio rerio 33019 R-DRE-197235 https://reactome.org/PathwayBrowser/#/R-DRE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 33019 R-DRE-197271 https://reactome.org/PathwayBrowser/#/R-DRE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Danio rerio 33019 R-DRE-200512 https://reactome.org/PathwayBrowser/#/R-DRE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 33019 R-DRE-201035 https://reactome.org/PathwayBrowser/#/R-DRE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Danio rerio 33019 R-DRE-2046085 https://reactome.org/PathwayBrowser/#/R-DRE-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Danio rerio 33019 R-DRE-2046098 https://reactome.org/PathwayBrowser/#/R-DRE-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Danio rerio 33019 R-DRE-2162192 https://reactome.org/PathwayBrowser/#/R-DRE-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Danio rerio 33019 R-DRE-2162253 https://reactome.org/PathwayBrowser/#/R-DRE-2162253 PDSS1,2 ligates FPP to IPPP IEA Danio rerio 33019 R-DRE-2395818 https://reactome.org/PathwayBrowser/#/R-DRE-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Danio rerio 33019 R-DRE-2395849 https://reactome.org/PathwayBrowser/#/R-DRE-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Danio rerio 33019 R-DRE-2395872 https://reactome.org/PathwayBrowser/#/R-DRE-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Danio rerio 33019 R-DRE-2408551 https://reactome.org/PathwayBrowser/#/R-DRE-2408551 SeMet is converted to AdoSeMet by MAT IEA Danio rerio 33019 R-DRE-2509827 https://reactome.org/PathwayBrowser/#/R-DRE-2509827 ITPA hydrolyses ITP to IMP IEA Danio rerio 33019 R-DRE-2509831 https://reactome.org/PathwayBrowser/#/R-DRE-2509831 ITPA hydrolyses XTP to XMP IEA Danio rerio 33019 R-DRE-2509838 https://reactome.org/PathwayBrowser/#/R-DRE-2509838 ITPA hydrolyses dITP to dIMP IEA Danio rerio 33019 R-DRE-2530501 https://reactome.org/PathwayBrowser/#/R-DRE-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Danio rerio 33019 R-DRE-2990833 https://reactome.org/PathwayBrowser/#/R-DRE-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Danio rerio 33019 R-DRE-392513 https://reactome.org/PathwayBrowser/#/R-DRE-392513 Rap1 signal termination by Rap1GAPs IEA Danio rerio 33019 R-DRE-4084982 https://reactome.org/PathwayBrowser/#/R-DRE-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Danio rerio 33019 R-DRE-434382 https://reactome.org/PathwayBrowser/#/R-DRE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Danio rerio 33019 R-DRE-446204 https://reactome.org/PathwayBrowser/#/R-DRE-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Danio rerio 33019 R-DRE-449937 https://reactome.org/PathwayBrowser/#/R-DRE-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Danio rerio 33019 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 33019 R-DRE-5226964 https://reactome.org/PathwayBrowser/#/R-DRE-5226964 ANKH transports PPi from cytosol to extracellular region IEA Danio rerio 33019 R-DRE-548843 https://reactome.org/PathwayBrowser/#/R-DRE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Danio rerio 33019 R-DRE-5603114 https://reactome.org/PathwayBrowser/#/R-DRE-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Danio rerio 33019 R-DRE-5610727 https://reactome.org/PathwayBrowser/#/R-DRE-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Danio rerio 33019 R-DRE-5649723 https://reactome.org/PathwayBrowser/#/R-DRE-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Danio rerio 33019 R-DRE-5649883 https://reactome.org/PathwayBrowser/#/R-DRE-5649883 POLB-mediated DNA strand displacement synthesis IEA Danio rerio 33019 R-DRE-5656148 https://reactome.org/PathwayBrowser/#/R-DRE-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Danio rerio 33019 R-DRE-5694494 https://reactome.org/PathwayBrowser/#/R-DRE-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Danio rerio 33019 R-DRE-5696004 https://reactome.org/PathwayBrowser/#/R-DRE-5696004 ACSF2 ligates CoA-SH to MCFA IEA Danio rerio 33019 R-DRE-6788912 https://reactome.org/PathwayBrowser/#/R-DRE-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Danio rerio 33019 R-DRE-6806674 https://reactome.org/PathwayBrowser/#/R-DRE-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Danio rerio 33019 R-DRE-71732 https://reactome.org/PathwayBrowser/#/R-DRE-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Danio rerio 33019 R-DRE-73666 https://reactome.org/PathwayBrowser/#/R-DRE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Danio rerio 33019 R-DRE-73815 https://reactome.org/PathwayBrowser/#/R-DRE-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Danio rerio 33019 R-DRE-74213 https://reactome.org/PathwayBrowser/#/R-DRE-74213 APRT catalyzes the conversion of adenine to AMP IEA Danio rerio 33019 R-DRE-74215 https://reactome.org/PathwayBrowser/#/R-DRE-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Danio rerio 33019 R-DRE-8852128 https://reactome.org/PathwayBrowser/#/R-DRE-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Danio rerio 33019 R-DRE-8852131 https://reactome.org/PathwayBrowser/#/R-DRE-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Danio rerio 33019 R-DRE-8852132 https://reactome.org/PathwayBrowser/#/R-DRE-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Danio rerio 33019 R-DRE-8852134 https://reactome.org/PathwayBrowser/#/R-DRE-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Danio rerio 33019 R-DRE-8870469 https://reactome.org/PathwayBrowser/#/R-DRE-8870469 RGGT geranylgeranylates RAB proteins IEA Danio rerio 33019 R-DRE-8939959 https://reactome.org/PathwayBrowser/#/R-DRE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Danio rerio 33019 R-DRE-8951648 https://reactome.org/PathwayBrowser/#/R-DRE-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Danio rerio 33019 R-DRE-8951656 https://reactome.org/PathwayBrowser/#/R-DRE-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Danio rerio 33019 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 33019 R-DRE-9731228 https://reactome.org/PathwayBrowser/#/R-DRE-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Danio rerio 33019 R-DRE-9731590 https://reactome.org/PathwayBrowser/#/R-DRE-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Danio rerio 33019 R-DRE-9731613 https://reactome.org/PathwayBrowser/#/R-DRE-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Danio rerio 33019 R-DRE-9731632 https://reactome.org/PathwayBrowser/#/R-DRE-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Danio rerio 33019 R-DRE-9748951 https://reactome.org/PathwayBrowser/#/R-DRE-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Danio rerio 33019 R-DRE-9749971 https://reactome.org/PathwayBrowser/#/R-DRE-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Danio rerio 33019 R-DRE-9755030 https://reactome.org/PathwayBrowser/#/R-DRE-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Danio rerio 33019 R-DRE-983140 https://reactome.org/PathwayBrowser/#/R-DRE-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Danio rerio 33019 R-DRE-983153 https://reactome.org/PathwayBrowser/#/R-DRE-983153 E1 mediated ubiquitin activation IEA Danio rerio 33019 R-DRE-983156 https://reactome.org/PathwayBrowser/#/R-DRE-983156 Polyubiquitination of substrate IEA Danio rerio 33019 R-GGA-110311 https://reactome.org/PathwayBrowser/#/R-GGA-110311 POLZ extends translesion synthesis IEA Gallus gallus 33019 R-GGA-110317 https://reactome.org/PathwayBrowser/#/R-GGA-110317 Insertion of correct bases opposite the lesion by POLH IEA Gallus gallus 33019 R-GGA-110319 https://reactome.org/PathwayBrowser/#/R-GGA-110319 Elongation by POLH IEA Gallus gallus 33019 R-GGA-111264 https://reactome.org/PathwayBrowser/#/R-GGA-111264 Addition of nucleotides between position +11 and +30 IEA Gallus gallus 33019 R-GGA-111930 https://reactome.org/PathwayBrowser/#/R-GGA-111930 Adenylate cyclase produces cAMP IEA Gallus gallus 33019 R-GGA-1483081 https://reactome.org/PathwayBrowser/#/R-GGA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Gallus gallus 33019 R-GGA-1483121 https://reactome.org/PathwayBrowser/#/R-GGA-1483121 PA is converted to CDP-DAG by CDS1 IEA Gallus gallus 33019 R-GGA-1483165 https://reactome.org/PathwayBrowser/#/R-GGA-1483165 PA is converted to CDP-DAG by CDS2 IEA Gallus gallus 33019 R-GGA-1483190 https://reactome.org/PathwayBrowser/#/R-GGA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Gallus gallus 33019 R-GGA-159425 https://reactome.org/PathwayBrowser/#/R-GGA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 33019 R-GGA-159443 https://reactome.org/PathwayBrowser/#/R-GGA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 33019 R-GGA-159567 https://reactome.org/PathwayBrowser/#/R-GGA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Gallus gallus 33019 R-GGA-170676 https://reactome.org/PathwayBrowser/#/R-GGA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Gallus gallus 33019 R-GGA-174124 https://reactome.org/PathwayBrowser/#/R-GGA-174124 Dephosphorylation of phospho-Cdh1 IEA Gallus gallus 33019 R-GGA-174391 https://reactome.org/PathwayBrowser/#/R-GGA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Gallus gallus 33019 R-GGA-174392 https://reactome.org/PathwayBrowser/#/R-GGA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Gallus gallus 33019 R-GGA-177157 https://reactome.org/PathwayBrowser/#/R-GGA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Gallus gallus 33019 R-GGA-187586 https://reactome.org/PathwayBrowser/#/R-GGA-187586 ATP + aspartate + citrulline <=> argininosuccinate + AMP + pyrophosphate TAS Gallus gallus 33019 R-GGA-191303 https://reactome.org/PathwayBrowser/#/R-GGA-191303 FDPS dimer transfers IPPP to GPP IEA Gallus gallus 33019 R-GGA-191322 https://reactome.org/PathwayBrowser/#/R-GGA-191322 FDPS dimer transfers IPPP to DMAPP IEA Gallus gallus 33019 R-GGA-191402 https://reactome.org/PathwayBrowser/#/R-GGA-191402 Reduction of presqualene diphosphate to form squalene IEA Gallus gallus 33019 R-GGA-191405 https://reactome.org/PathwayBrowser/#/R-GGA-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Gallus gallus 33019 R-GGA-192137 https://reactome.org/PathwayBrowser/#/R-GGA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 33019 R-GGA-193401 https://reactome.org/PathwayBrowser/#/R-GGA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 33019 R-GGA-193407 https://reactome.org/PathwayBrowser/#/R-GGA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 33019 R-GGA-193424 https://reactome.org/PathwayBrowser/#/R-GGA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 33019 R-GGA-193711 https://reactome.org/PathwayBrowser/#/R-GGA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 33019 R-GGA-193727 https://reactome.org/PathwayBrowser/#/R-GGA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 33019 R-GGA-193743 https://reactome.org/PathwayBrowser/#/R-GGA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 33019 R-GGA-193766 https://reactome.org/PathwayBrowser/#/R-GGA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 33019 R-GGA-196753 https://reactome.org/PathwayBrowser/#/R-GGA-196753 2xPPCS ligates PPanK with Cys IEA Gallus gallus 33019 R-GGA-196754 https://reactome.org/PathwayBrowser/#/R-GGA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Gallus gallus 33019 R-GGA-196929 https://reactome.org/PathwayBrowser/#/R-GGA-196929 FLAD1 phosphorylates FMN IEA Gallus gallus 33019 R-GGA-197186 https://reactome.org/PathwayBrowser/#/R-GGA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Gallus gallus 33019 R-GGA-197235 https://reactome.org/PathwayBrowser/#/R-GGA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 33019 R-GGA-197250 https://reactome.org/PathwayBrowser/#/R-GGA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Gallus gallus 33019 R-GGA-197268 https://reactome.org/PathwayBrowser/#/R-GGA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Gallus gallus 33019 R-GGA-197271 https://reactome.org/PathwayBrowser/#/R-GGA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Gallus gallus 33019 R-GGA-200474 https://reactome.org/PathwayBrowser/#/R-GGA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 33019 R-GGA-200512 https://reactome.org/PathwayBrowser/#/R-GGA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 33019 R-GGA-201035 https://reactome.org/PathwayBrowser/#/R-GGA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Gallus gallus 33019 R-GGA-2046085 https://reactome.org/PathwayBrowser/#/R-GGA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Gallus gallus 33019 R-GGA-2046098 https://reactome.org/PathwayBrowser/#/R-GGA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Gallus gallus 33019 R-GGA-2162192 https://reactome.org/PathwayBrowser/#/R-GGA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Gallus gallus 33019 R-GGA-2162253 https://reactome.org/PathwayBrowser/#/R-GGA-2162253 PDSS1,2 ligates FPP to IPPP IEA Gallus gallus 33019 R-GGA-2395818 https://reactome.org/PathwayBrowser/#/R-GGA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Gallus gallus 33019 R-GGA-2395849 https://reactome.org/PathwayBrowser/#/R-GGA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 33019 R-GGA-2395869 https://reactome.org/PathwayBrowser/#/R-GGA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 33019 R-GGA-2395872 https://reactome.org/PathwayBrowser/#/R-GGA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Gallus gallus 33019 R-GGA-2408551 https://reactome.org/PathwayBrowser/#/R-GGA-2408551 SeMet is converted to AdoSeMet by MAT IEA Gallus gallus 33019 R-GGA-2509827 https://reactome.org/PathwayBrowser/#/R-GGA-2509827 ITPA hydrolyses ITP to IMP IEA Gallus gallus 33019 R-GGA-2509831 https://reactome.org/PathwayBrowser/#/R-GGA-2509831 ITPA hydrolyses XTP to XMP IEA Gallus gallus 33019 R-GGA-2509838 https://reactome.org/PathwayBrowser/#/R-GGA-2509838 ITPA hydrolyses dITP to dIMP IEA Gallus gallus 33019 R-GGA-2990833 https://reactome.org/PathwayBrowser/#/R-GGA-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Gallus gallus 33019 R-GGA-2993447 https://reactome.org/PathwayBrowser/#/R-GGA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Gallus gallus 33019 R-GGA-2993799 https://reactome.org/PathwayBrowser/#/R-GGA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Gallus gallus 33019 R-GGA-2993814 https://reactome.org/PathwayBrowser/#/R-GGA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Gallus gallus 33019 R-GGA-2995330 https://reactome.org/PathwayBrowser/#/R-GGA-2995330 COX10 transforms heme to heme O IEA Gallus gallus 33019 R-GGA-389622 https://reactome.org/PathwayBrowser/#/R-GGA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 33019 R-GGA-389632 https://reactome.org/PathwayBrowser/#/R-GGA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 33019 R-GGA-389758 https://reactome.org/PathwayBrowser/#/R-GGA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Gallus gallus 33019 R-GGA-392513 https://reactome.org/PathwayBrowser/#/R-GGA-392513 Rap1 signal termination by Rap1GAPs IEA Gallus gallus 33019 R-GGA-4084982 https://reactome.org/PathwayBrowser/#/R-GGA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Gallus gallus 33019 R-GGA-417122 https://reactome.org/PathwayBrowser/#/R-GGA-417122 Elongation and translocation of the telomeric chromosome end IEA Gallus gallus 33019 R-GGA-417127 https://reactome.org/PathwayBrowser/#/R-GGA-417127 Elongation and translocation of the extended telomeric chromosome end IEA Gallus gallus 33019 R-GGA-419152 https://reactome.org/PathwayBrowser/#/R-GGA-419152 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate TAS Gallus gallus 33019 R-GGA-419462 https://reactome.org/PathwayBrowser/#/R-GGA-419462 orotate + 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) <=> orotidine 5'-monophosphate (OMP) + pyrophosphate IEA Gallus gallus 33019 R-GGA-421218 https://reactome.org/PathwayBrowser/#/R-GGA-421218 xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate IEA Gallus gallus 33019 R-GGA-434382 https://reactome.org/PathwayBrowser/#/R-GGA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Gallus gallus 33019 R-GGA-446204 https://reactome.org/PathwayBrowser/#/R-GGA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Gallus gallus 33019 R-GGA-449911 https://reactome.org/PathwayBrowser/#/R-GGA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Gallus gallus 33019 R-GGA-449937 https://reactome.org/PathwayBrowser/#/R-GGA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Gallus gallus 33019 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 33019 R-GGA-5226964 https://reactome.org/PathwayBrowser/#/R-GGA-5226964 ANKH transports PPi from cytosol to extracellular region IEA Gallus gallus 33019 R-GGA-5358475 https://reactome.org/PathwayBrowser/#/R-GGA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Gallus gallus 33019 R-GGA-5358592 https://reactome.org/PathwayBrowser/#/R-GGA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Gallus gallus 33019 R-GGA-548843 https://reactome.org/PathwayBrowser/#/R-GGA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Gallus gallus 33019 R-GGA-5603114 https://reactome.org/PathwayBrowser/#/R-GGA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Gallus gallus 33019 R-GGA-5610727 https://reactome.org/PathwayBrowser/#/R-GGA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Gallus gallus 33019 R-GGA-5655892 https://reactome.org/PathwayBrowser/#/R-GGA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Gallus gallus 33019 R-GGA-5655965 https://reactome.org/PathwayBrowser/#/R-GGA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Gallus gallus 33019 R-GGA-5656148 https://reactome.org/PathwayBrowser/#/R-GGA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Gallus gallus 33019 R-GGA-5656158 https://reactome.org/PathwayBrowser/#/R-GGA-5656158 POLZ elongates POLI-incorporated dNMP IEA Gallus gallus 33019 R-GGA-5687360 https://reactome.org/PathwayBrowser/#/R-GGA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Gallus gallus 33019 R-GGA-5687640 https://reactome.org/PathwayBrowser/#/R-GGA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Gallus gallus 33019 R-GGA-5691001 https://reactome.org/PathwayBrowser/#/R-GGA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Gallus gallus 33019 R-GGA-5693593 https://reactome.org/PathwayBrowser/#/R-GGA-5693593 D-loop extension by DNA polymerases IEA Gallus gallus 33019 R-GGA-5694494 https://reactome.org/PathwayBrowser/#/R-GGA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Gallus gallus 33019 R-GGA-5695957 https://reactome.org/PathwayBrowser/#/R-GGA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Gallus gallus 33019 R-GGA-5696004 https://reactome.org/PathwayBrowser/#/R-GGA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Gallus gallus 33019 R-GGA-6781824 https://reactome.org/PathwayBrowser/#/R-GGA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Gallus gallus 33019 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus 33019 R-GGA-6787533 https://reactome.org/PathwayBrowser/#/R-GGA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Gallus gallus 33019 R-GGA-6788912 https://reactome.org/PathwayBrowser/#/R-GGA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Gallus gallus 33019 R-GGA-6806674 https://reactome.org/PathwayBrowser/#/R-GGA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Gallus gallus 33019 R-GGA-70286 https://reactome.org/PathwayBrowser/#/R-GGA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Gallus gallus 33019 R-GGA-70577 https://reactome.org/PathwayBrowser/#/R-GGA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Gallus gallus 33019 R-GGA-70599 https://reactome.org/PathwayBrowser/#/R-GGA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Gallus gallus 33019 R-GGA-71732 https://reactome.org/PathwayBrowser/#/R-GGA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Gallus gallus 33019 R-GGA-71735 https://reactome.org/PathwayBrowser/#/R-GGA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Gallus gallus 33019 R-GGA-73567 https://reactome.org/PathwayBrowser/#/R-GGA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Gallus gallus 33019 R-GGA-73666 https://reactome.org/PathwayBrowser/#/R-GGA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Gallus gallus 33019 R-GGA-73792 https://reactome.org/PathwayBrowser/#/R-GGA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Gallus gallus 33019 R-GGA-73815 https://reactome.org/PathwayBrowser/#/R-GGA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Gallus gallus 33019 R-GGA-74213 https://reactome.org/PathwayBrowser/#/R-GGA-74213 APRT catalyzes the conversion of adenine to AMP IEA Gallus gallus 33019 R-GGA-74215 https://reactome.org/PathwayBrowser/#/R-GGA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Gallus gallus 33019 R-GGA-75850 https://reactome.org/PathwayBrowser/#/R-GGA-75850 Addition of the third nucleotide on the nascent transcript IEA Gallus gallus 33019 R-GGA-75864 https://reactome.org/PathwayBrowser/#/R-GGA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Gallus gallus 33019 R-GGA-75869 https://reactome.org/PathwayBrowser/#/R-GGA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Gallus gallus 33019 R-GGA-75873 https://reactome.org/PathwayBrowser/#/R-GGA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Gallus gallus 33019 R-GGA-76576 https://reactome.org/PathwayBrowser/#/R-GGA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Gallus gallus 33019 R-GGA-8852128 https://reactome.org/PathwayBrowser/#/R-GGA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Gallus gallus 33019 R-GGA-8852131 https://reactome.org/PathwayBrowser/#/R-GGA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Gallus gallus 33019 R-GGA-8852132 https://reactome.org/PathwayBrowser/#/R-GGA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Gallus gallus 33019 R-GGA-8852134 https://reactome.org/PathwayBrowser/#/R-GGA-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Gallus gallus 33019 R-GGA-8875071 https://reactome.org/PathwayBrowser/#/R-GGA-8875071 ACSS3 ligates CoA to CH3COO- IEA Gallus gallus 33019 R-GGA-8939959 https://reactome.org/PathwayBrowser/#/R-GGA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Gallus gallus 33019 R-GGA-8951648 https://reactome.org/PathwayBrowser/#/R-GGA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Gallus gallus 33019 R-GGA-8951656 https://reactome.org/PathwayBrowser/#/R-GGA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Gallus gallus 33019 R-GGA-9008822 https://reactome.org/PathwayBrowser/#/R-GGA-9008822 PPM1D dephosphorylates RUNX2 IEA Gallus gallus 33019 R-GGA-947531 https://reactome.org/PathwayBrowser/#/R-GGA-947531 Molybdenum ion transfer onto molybdopterin IEA Gallus gallus 33019 R-GGA-947535 https://reactome.org/PathwayBrowser/#/R-GGA-947535 Cyclisation of GTP to precursor Z IEA Gallus gallus 33019 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus 33019 R-GGA-9613497 https://reactome.org/PathwayBrowser/#/R-GGA-9613497 Unwinding DNA for the nascent transcript IEA Gallus gallus 33019 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 33019 R-GGA-9717830 https://reactome.org/PathwayBrowser/#/R-GGA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Gallus gallus 33019 R-GGA-9717834 https://reactome.org/PathwayBrowser/#/R-GGA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Gallus gallus 33019 R-GGA-9731228 https://reactome.org/PathwayBrowser/#/R-GGA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Gallus gallus 33019 R-GGA-9731590 https://reactome.org/PathwayBrowser/#/R-GGA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Gallus gallus 33019 R-GGA-9731613 https://reactome.org/PathwayBrowser/#/R-GGA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Gallus gallus 33019 R-GGA-9731632 https://reactome.org/PathwayBrowser/#/R-GGA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Gallus gallus 33019 R-GGA-9734535 https://reactome.org/PathwayBrowser/#/R-GGA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Gallus gallus 33019 R-GGA-9748951 https://reactome.org/PathwayBrowser/#/R-GGA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Gallus gallus 33019 R-GGA-9748957 https://reactome.org/PathwayBrowser/#/R-GGA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Gallus gallus 33019 R-GGA-9749971 https://reactome.org/PathwayBrowser/#/R-GGA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Gallus gallus 33019 R-GGA-9750555 https://reactome.org/PathwayBrowser/#/R-GGA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Gallus gallus 33019 R-GGA-9755030 https://reactome.org/PathwayBrowser/#/R-GGA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Gallus gallus 33019 R-GGA-9760094 https://reactome.org/PathwayBrowser/#/R-GGA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Gallus gallus 33019 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus 33019 R-GGA-983153 https://reactome.org/PathwayBrowser/#/R-GGA-983153 E1 mediated ubiquitin activation IEA Gallus gallus 33019 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus 33019 R-HSA-110311 https://reactome.org/PathwayBrowser/#/R-HSA-110311 POLZ extends translesion synthesis TAS Homo sapiens 33019 R-HSA-110317 https://reactome.org/PathwayBrowser/#/R-HSA-110317 Insertion of correct bases opposite the lesion by POLH TAS Homo sapiens 33019 R-HSA-110319 https://reactome.org/PathwayBrowser/#/R-HSA-110319 Elongation by POLH TAS Homo sapiens 33019 R-HSA-110368 https://reactome.org/PathwayBrowser/#/R-HSA-110368 POLD,POLE-mediated DNA strand displacement synthesis TAS Homo sapiens 33019 R-HSA-111253 https://reactome.org/PathwayBrowser/#/R-HSA-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site TAS Homo sapiens 33019 R-HSA-111264 https://reactome.org/PathwayBrowser/#/R-HSA-111264 Addition of nucleotides between position +11 and +30 TAS Homo sapiens 33019 R-HSA-111930 https://reactome.org/PathwayBrowser/#/R-HSA-111930 Adenylate cyclase produces cAMP TAS Homo sapiens 33019 R-HSA-1169394 https://reactome.org/PathwayBrowser/#/R-HSA-1169394 ISGylation of IRF3 TAS Homo sapiens 33019 R-HSA-1169395 https://reactome.org/PathwayBrowser/#/R-HSA-1169395 ISGylation of viral protein NS1 TAS Homo sapiens 33019 R-HSA-1169397 https://reactome.org/PathwayBrowser/#/R-HSA-1169397 Activation of ISG15 by UBA7 E1 ligase TAS Homo sapiens 33019 R-HSA-1169398 https://reactome.org/PathwayBrowser/#/R-HSA-1169398 ISGylation of host protein filamin B TAS Homo sapiens 33019 R-HSA-1169402 https://reactome.org/PathwayBrowser/#/R-HSA-1169402 ISGylation of E2 conjugating enzymes TAS Homo sapiens 33019 R-HSA-1169405 https://reactome.org/PathwayBrowser/#/R-HSA-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) TAS Homo sapiens 33019 R-HSA-1169406 https://reactome.org/PathwayBrowser/#/R-HSA-1169406 ISGylation of host proteins TAS Homo sapiens 33019 R-HSA-1483081 https://reactome.org/PathwayBrowser/#/R-HSA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer TAS Homo sapiens 33019 R-HSA-1483121 https://reactome.org/PathwayBrowser/#/R-HSA-1483121 PA is converted to CDP-DAG by CDS1 TAS Homo sapiens 33019 R-HSA-1483165 https://reactome.org/PathwayBrowser/#/R-HSA-1483165 PA is converted to CDP-DAG by CDS2 TAS Homo sapiens 33019 R-HSA-1483190 https://reactome.org/PathwayBrowser/#/R-HSA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 TAS Homo sapiens 33019 R-HSA-159425 https://reactome.org/PathwayBrowser/#/R-HSA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 33019 R-HSA-159443 https://reactome.org/PathwayBrowser/#/R-HSA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-159567 https://reactome.org/PathwayBrowser/#/R-HSA-159567 ACSM2B-like proteins transform ST to ST-CoA TAS Homo sapiens 33019 R-HSA-164377 https://reactome.org/PathwayBrowser/#/R-HSA-164377 Activated Adenylate cyclase catalyses cAMP synthesis TAS Homo sapiens 33019 R-HSA-164504 https://reactome.org/PathwayBrowser/#/R-HSA-164504 Synthesis of minus strand strong stop DNA (-sssDNA) TAS Homo sapiens 33019 R-HSA-167113 https://reactome.org/PathwayBrowser/#/R-HSA-167113 Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition IEA Homo sapiens 33019 R-HSA-167115 https://reactome.org/PathwayBrowser/#/R-HSA-167115 Addition of nucleotides between position +11 and +30 on HIV-1 transcript IEA Homo sapiens 33019 R-HSA-167117 https://reactome.org/PathwayBrowser/#/R-HSA-167117 Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition IEA Homo sapiens 33019 R-HSA-167121 https://reactome.org/PathwayBrowser/#/R-HSA-167121 Addition of the third nucleotide on the nascent HIV-1 transcript IEA Homo sapiens 33019 R-HSA-167134 https://reactome.org/PathwayBrowser/#/R-HSA-167134 Newly formed phosphodiester bond stabilized and PPi released IEA Homo sapiens 33019 R-HSA-167136 https://reactome.org/PathwayBrowser/#/R-HSA-167136 Addition of nucleotides 5 through 9 on the growing HIV-1 transcript IEA Homo sapiens 33019 R-HSA-170676 https://reactome.org/PathwayBrowser/#/R-HSA-170676 Adenylate cyclase converts ATP into cyclic AMP TAS Homo sapiens 33019 R-HSA-174124 https://reactome.org/PathwayBrowser/#/R-HSA-174124 Dephosphorylation of phospho-Cdh1 TAS Homo sapiens 33019 R-HSA-174391 https://reactome.org/PathwayBrowser/#/R-HSA-174391 MAT1A multimers transfer Ado from ATP to L-Met TAS Homo sapiens 33019 R-HSA-174392 https://reactome.org/PathwayBrowser/#/R-HSA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS TAS Homo sapiens 33019 R-HSA-177157 https://reactome.org/PathwayBrowser/#/R-HSA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-191303 https://reactome.org/PathwayBrowser/#/R-HSA-191303 FDPS dimer transfers IPPP to GPP TAS Homo sapiens 33019 R-HSA-191322 https://reactome.org/PathwayBrowser/#/R-HSA-191322 FDPS dimer transfers IPPP to DMAPP TAS Homo sapiens 33019 R-HSA-191402 https://reactome.org/PathwayBrowser/#/R-HSA-191402 Reduction of presqualene diphosphate to form squalene TAS Homo sapiens 33019 R-HSA-191405 https://reactome.org/PathwayBrowser/#/R-HSA-191405 Two FPP molecules dimerize to form presqualene diphosphate TAS Homo sapiens 33019 R-HSA-192137 https://reactome.org/PathwayBrowser/#/R-HSA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 33019 R-HSA-193401 https://reactome.org/PathwayBrowser/#/R-HSA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 33019 R-HSA-193407 https://reactome.org/PathwayBrowser/#/R-HSA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 33019 R-HSA-193424 https://reactome.org/PathwayBrowser/#/R-HSA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 33019 R-HSA-193711 https://reactome.org/PathwayBrowser/#/R-HSA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 33019 R-HSA-193727 https://reactome.org/PathwayBrowser/#/R-HSA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 33019 R-HSA-193743 https://reactome.org/PathwayBrowser/#/R-HSA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 33019 R-HSA-193766 https://reactome.org/PathwayBrowser/#/R-HSA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 33019 R-HSA-196753 https://reactome.org/PathwayBrowser/#/R-HSA-196753 2xPPCS ligates PPanK with Cys TAS Homo sapiens 33019 R-HSA-196754 https://reactome.org/PathwayBrowser/#/R-HSA-196754 COASY transfers an adenylyl group from ATP to PPANT TAS Homo sapiens 33019 R-HSA-196929 https://reactome.org/PathwayBrowser/#/R-HSA-196929 FLAD1 phosphorylates FMN TAS Homo sapiens 33019 R-HSA-197186 https://reactome.org/PathwayBrowser/#/R-HSA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN TAS Homo sapiens 33019 R-HSA-197235 https://reactome.org/PathwayBrowser/#/R-HSA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 33019 R-HSA-197250 https://reactome.org/PathwayBrowser/#/R-HSA-197250 NAMPT transfers PRIB to NAM to form NAMN TAS Homo sapiens 33019 R-HSA-197268 https://reactome.org/PathwayBrowser/#/R-HSA-197268 QPRT transfers PRIB to QUIN to form NAMN TAS Homo sapiens 33019 R-HSA-197271 https://reactome.org/PathwayBrowser/#/R-HSA-197271 NADSYN1 hexamer amidates NAAD to NAD+ TAS Homo sapiens 33019 R-HSA-200474 https://reactome.org/PathwayBrowser/#/R-HSA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 33019 R-HSA-200512 https://reactome.org/PathwayBrowser/#/R-HSA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 33019 R-HSA-201035 https://reactome.org/PathwayBrowser/#/R-HSA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA TAS Homo sapiens 33019 R-HSA-2046085 https://reactome.org/PathwayBrowser/#/R-HSA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA TAS Homo sapiens 33019 R-HSA-2046098 https://reactome.org/PathwayBrowser/#/R-HSA-2046098 Activation of linoleic acid to linoleoyl-CoA TAS Homo sapiens 33019 R-HSA-2162192 https://reactome.org/PathwayBrowser/#/R-HSA-2162192 COQ2 ligates all-E-10PrP2 to PHB TAS Homo sapiens 33019 R-HSA-2162253 https://reactome.org/PathwayBrowser/#/R-HSA-2162253 PDSS1,2 ligates FPP to IPPP TAS Homo sapiens 33019 R-HSA-2395818 https://reactome.org/PathwayBrowser/#/R-HSA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP TAS Homo sapiens 33019 R-HSA-2395849 https://reactome.org/PathwayBrowser/#/R-HSA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 33019 R-HSA-2395869 https://reactome.org/PathwayBrowser/#/R-HSA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 33019 R-HSA-2395872 https://reactome.org/PathwayBrowser/#/R-HSA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP TAS Homo sapiens 33019 R-HSA-2408525 https://reactome.org/PathwayBrowser/#/R-HSA-2408525 H2SeO4 is converted to APSe by PAPSS1,2 IEA Homo sapiens 33019 R-HSA-2408526 https://reactome.org/PathwayBrowser/#/R-HSA-2408526 tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer TAS Homo sapiens 33019 R-HSA-2408546 https://reactome.org/PathwayBrowser/#/R-HSA-2408546 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex IEA Homo sapiens 33019 R-HSA-2408551 https://reactome.org/PathwayBrowser/#/R-HSA-2408551 SeMet is converted to AdoSeMet by MAT TAS Homo sapiens 33019 R-HSA-2509827 https://reactome.org/PathwayBrowser/#/R-HSA-2509827 ITPA hydrolyses ITP to IMP TAS Homo sapiens 33019 R-HSA-2509831 https://reactome.org/PathwayBrowser/#/R-HSA-2509831 ITPA hydrolyses XTP to XMP TAS Homo sapiens 33019 R-HSA-2509838 https://reactome.org/PathwayBrowser/#/R-HSA-2509838 ITPA hydrolyses dITP to dIMP TAS Homo sapiens 33019 R-HSA-2530501 https://reactome.org/PathwayBrowser/#/R-HSA-2530501 FNTA:FNTB transfers FARN to GNGT1 TAS Homo sapiens 33019 R-HSA-2730904 https://reactome.org/PathwayBrowser/#/R-HSA-2730904 Auto-ubiquitination of TRAF6 TAS Homo sapiens 33019 R-HSA-2990833 https://reactome.org/PathwayBrowser/#/R-HSA-2990833 Conjugation of SUMO1 to UBA2:SAE1 TAS Homo sapiens 33019 R-HSA-2993447 https://reactome.org/PathwayBrowser/#/R-HSA-2993447 HLCS biotinylates 6x(PCCA:PCCB) TAS Homo sapiens 33019 R-HSA-2993781 https://reactome.org/PathwayBrowser/#/R-HSA-2993781 Conjugation of SUMO3 to UBA2:SAE1 IEA Homo sapiens 33019 R-HSA-2993784 https://reactome.org/PathwayBrowser/#/R-HSA-2993784 Conjugation of SUMO2 to UBA2:SAE1 IEA Homo sapiens 33019 R-HSA-2993799 https://reactome.org/PathwayBrowser/#/R-HSA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 TAS Homo sapiens 33019 R-HSA-2993802 https://reactome.org/PathwayBrowser/#/R-HSA-2993802 HLCS biotinylates PC:Mn2+ TAS Homo sapiens 33019 R-HSA-2993814 https://reactome.org/PathwayBrowser/#/R-HSA-2993814 HLCS biotinylates ACACA:Mn2+ TAS Homo sapiens 33019 R-HSA-2995330 https://reactome.org/PathwayBrowser/#/R-HSA-2995330 COX10 transforms heme to heme O TAS Homo sapiens 33019 R-HSA-3244614 https://reactome.org/PathwayBrowser/#/R-HSA-3244614 cGAS produces cyclic GMP-AMP TAS Homo sapiens 33019 R-HSA-379844 https://reactome.org/PathwayBrowser/#/R-HSA-379844 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379848 https://reactome.org/PathwayBrowser/#/R-HSA-379848 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379861 https://reactome.org/PathwayBrowser/#/R-HSA-379861 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379864 https://reactome.org/PathwayBrowser/#/R-HSA-379864 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379865 https://reactome.org/PathwayBrowser/#/R-HSA-379865 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379867 https://reactome.org/PathwayBrowser/#/R-HSA-379867 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379887 https://reactome.org/PathwayBrowser/#/R-HSA-379887 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379893 https://reactome.org/PathwayBrowser/#/R-HSA-379893 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379974 https://reactome.org/PathwayBrowser/#/R-HSA-379974 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379977 https://reactome.org/PathwayBrowser/#/R-HSA-379977 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379980 https://reactome.org/PathwayBrowser/#/R-HSA-379980 tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379982 https://reactome.org/PathwayBrowser/#/R-HSA-379982 glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379992 https://reactome.org/PathwayBrowser/#/R-HSA-379992 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379993 https://reactome.org/PathwayBrowser/#/R-HSA-379993 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379994 https://reactome.org/PathwayBrowser/#/R-HSA-379994 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-379996 https://reactome.org/PathwayBrowser/#/R-HSA-379996 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380002 https://reactome.org/PathwayBrowser/#/R-HSA-380002 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380008 https://reactome.org/PathwayBrowser/#/R-HSA-380008 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380042 https://reactome.org/PathwayBrowser/#/R-HSA-380042 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380048 https://reactome.org/PathwayBrowser/#/R-HSA-380048 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380157 https://reactome.org/PathwayBrowser/#/R-HSA-380157 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380158 https://reactome.org/PathwayBrowser/#/R-HSA-380158 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate IEA Homo sapiens 33019 R-HSA-380170 https://reactome.org/PathwayBrowser/#/R-HSA-380170 tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380176 https://reactome.org/PathwayBrowser/#/R-HSA-380176 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380177 https://reactome.org/PathwayBrowser/#/R-HSA-380177 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate IEA Homo sapiens 33019 R-HSA-380198 https://reactome.org/PathwayBrowser/#/R-HSA-380198 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate IEA Homo sapiens 33019 R-HSA-380199 https://reactome.org/PathwayBrowser/#/R-HSA-380199 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate IEA Homo sapiens 33019 R-HSA-380200 https://reactome.org/PathwayBrowser/#/R-HSA-380200 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380201 https://reactome.org/PathwayBrowser/#/R-HSA-380201 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate IEA Homo sapiens 33019 R-HSA-380203 https://reactome.org/PathwayBrowser/#/R-HSA-380203 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380216 https://reactome.org/PathwayBrowser/#/R-HSA-380216 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate IEA Homo sapiens 33019 R-HSA-380222 https://reactome.org/PathwayBrowser/#/R-HSA-380222 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380224 https://reactome.org/PathwayBrowser/#/R-HSA-380224 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380227 https://reactome.org/PathwayBrowser/#/R-HSA-380227 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate IEA Homo sapiens 33019 R-HSA-380229 https://reactome.org/PathwayBrowser/#/R-HSA-380229 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380233 https://reactome.org/PathwayBrowser/#/R-HSA-380233 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380234 https://reactome.org/PathwayBrowser/#/R-HSA-380234 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380239 https://reactome.org/PathwayBrowser/#/R-HSA-380239 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380240 https://reactome.org/PathwayBrowser/#/R-HSA-380240 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-380241 https://reactome.org/PathwayBrowser/#/R-HSA-380241 glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-381607 https://reactome.org/PathwayBrowser/#/R-HSA-381607 Activated Adenylyl cyclase synthesizes cyclic AMP TAS Homo sapiens 33019 R-HSA-389622 https://reactome.org/PathwayBrowser/#/R-HSA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-389632 https://reactome.org/PathwayBrowser/#/R-HSA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-389758 https://reactome.org/PathwayBrowser/#/R-HSA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases TAS Homo sapiens 33019 R-HSA-392129 https://reactome.org/PathwayBrowser/#/R-HSA-392129 Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate IEA Homo sapiens 33019 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 33019 R-HSA-392513 https://reactome.org/PathwayBrowser/#/R-HSA-392513 Rap1 signal termination by Rap1GAPs TAS Homo sapiens 33019 R-HSA-4084982 https://reactome.org/PathwayBrowser/#/R-HSA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac TAS Homo sapiens 33019 R-HSA-4167511 https://reactome.org/PathwayBrowser/#/R-HSA-4167511 HLCS biotinylates ACACB TAS Homo sapiens 33019 R-HSA-434382 https://reactome.org/PathwayBrowser/#/R-HSA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell TAS Homo sapiens 33019 R-HSA-4419986 https://reactome.org/PathwayBrowser/#/R-HSA-4419986 Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL TAS Homo sapiens 33019 R-HSA-442715 https://reactome.org/PathwayBrowser/#/R-HSA-442715 Calmodulin-activated adenylate cyclases ADCY1 and ADCY8 generate cAMP IEA Homo sapiens 33019 R-HSA-446204 https://reactome.org/PathwayBrowser/#/R-HSA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine TAS Homo sapiens 33019 R-HSA-446221 https://reactome.org/PathwayBrowser/#/R-HSA-446221 Mannose-1-phosphate converted to GDP-Mannose IEA Homo sapiens 33019 R-HSA-449911 https://reactome.org/PathwayBrowser/#/R-HSA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] TAS Homo sapiens 33019 R-HSA-449937 https://reactome.org/PathwayBrowser/#/R-HSA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] TAS Homo sapiens 33019 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 33019 R-HSA-5211224 https://reactome.org/PathwayBrowser/#/R-HSA-5211224 Anthrax cya catalyzes the conversion of ATP to cAMP TAS Homo sapiens 33019 R-HSA-5226964 https://reactome.org/PathwayBrowser/#/R-HSA-5226964 ANKH transports PPi from cytosol to extracellular region TAS Homo sapiens 33019 R-HSA-5358475 https://reactome.org/PathwayBrowser/#/R-HSA-5358475 DPH6 ligates ammonium to diphthine-EEF2 TAS Homo sapiens 33019 R-HSA-5358592 https://reactome.org/PathwayBrowser/#/R-HSA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA TAS Homo sapiens 33019 R-HSA-548843 https://reactome.org/PathwayBrowser/#/R-HSA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA TAS Homo sapiens 33019 R-HSA-5603114 https://reactome.org/PathwayBrowser/#/R-HSA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met TAS Homo sapiens 33019 R-HSA-5607756 https://reactome.org/PathwayBrowser/#/R-HSA-5607756 TRAF6 oligomer autoubiquitinates TAS Homo sapiens 33019 R-HSA-5607757 https://reactome.org/PathwayBrowser/#/R-HSA-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 TAS Homo sapiens 33019 R-HSA-5610727 https://reactome.org/PathwayBrowser/#/R-HSA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner TAS Homo sapiens 33019 R-HSA-5649723 https://reactome.org/PathwayBrowser/#/R-HSA-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution TAS Homo sapiens 33019 R-HSA-5649883 https://reactome.org/PathwayBrowser/#/R-HSA-5649883 POLB-mediated DNA strand displacement synthesis TAS Homo sapiens 33019 R-HSA-5653840 https://reactome.org/PathwayBrowser/#/R-HSA-5653840 POLD,POLE complete replication of damaged DNA after TLS TAS Homo sapiens 33019 R-HSA-5655892 https://reactome.org/PathwayBrowser/#/R-HSA-5655892 POLK incorporates dNMP opposite to damaged DNA base TAS Homo sapiens 33019 R-HSA-5655965 https://reactome.org/PathwayBrowser/#/R-HSA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini TAS Homo sapiens 33019 R-HSA-5656148 https://reactome.org/PathwayBrowser/#/R-HSA-5656148 POLI incorporates dNMP opposite to damaged DNA base TAS Homo sapiens 33019 R-HSA-5656158 https://reactome.org/PathwayBrowser/#/R-HSA-5656158 POLZ elongates POLI-incorporated dNMP TAS Homo sapiens 33019 R-HSA-5687360 https://reactome.org/PathwayBrowser/#/R-HSA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps TAS Homo sapiens 33019 R-HSA-5687640 https://reactome.org/PathwayBrowser/#/R-HSA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ TAS Homo sapiens 33019 R-HSA-5691001 https://reactome.org/PathwayBrowser/#/R-HSA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER TAS Homo sapiens 33019 R-HSA-5693593 https://reactome.org/PathwayBrowser/#/R-HSA-5693593 D-loop extension by DNA polymerases TAS Homo sapiens 33019 R-HSA-5694494 https://reactome.org/PathwayBrowser/#/R-HSA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA TAS Homo sapiens 33019 R-HSA-5695957 https://reactome.org/PathwayBrowser/#/R-HSA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA TAS Homo sapiens 33019 R-HSA-5696004 https://reactome.org/PathwayBrowser/#/R-HSA-5696004 ACSF2 ligates CoA-SH to MCFA TAS Homo sapiens 33019 R-HSA-5696007 https://reactome.org/PathwayBrowser/#/R-HSA-5696007 ACSF3 ligates CoA-SH to VLCFA TAS Homo sapiens 33019 R-HSA-5696807 https://reactome.org/PathwayBrowser/#/R-HSA-5696807 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 33019 R-HSA-5696816 https://reactome.org/PathwayBrowser/#/R-HSA-5696816 tRNA ligase complex ligates tRNA exons TAS Homo sapiens 33019 R-HSA-6781824 https://reactome.org/PathwayBrowser/#/R-HSA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template TAS Homo sapiens 33019 R-HSA-6782208 https://reactome.org/PathwayBrowser/#/R-HSA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER TAS Homo sapiens 33019 R-HSA-6782434 https://reactome.org/PathwayBrowser/#/R-HSA-6782434 THG1L transfers GMP to 5' end of tRNA(His) TAS Homo sapiens 33019 R-HSA-6784462 https://reactome.org/PathwayBrowser/#/R-HSA-6784462 TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs IEA Homo sapiens 33019 R-HSA-6786166 https://reactome.org/PathwayBrowser/#/R-HSA-6786166 Translesion synthesis across unhooked ICL by POLN TAS Homo sapiens 33019 R-HSA-6786257 https://reactome.org/PathwayBrowser/#/R-HSA-6786257 DCTPP1 hydrolyses 5idCTP IEA Homo sapiens 33019 R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 33019 R-HSA-6787533 https://reactome.org/PathwayBrowser/#/R-HSA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc TAS Homo sapiens 33019 R-HSA-6787567 https://reactome.org/PathwayBrowser/#/R-HSA-6787567 TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) TAS Homo sapiens 33019 R-HSA-6788912 https://reactome.org/PathwayBrowser/#/R-HSA-6788912 LHPP:Mg2+ dimer hydrolyses PPi TAS Homo sapiens 33019 R-HSA-6798345 https://reactome.org/PathwayBrowser/#/R-HSA-6798345 PXLP-GCAT dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA TAS Homo sapiens 33019 R-HSA-6806674 https://reactome.org/PathwayBrowser/#/R-HSA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) TAS Homo sapiens 33019 R-HSA-70286 https://reactome.org/PathwayBrowser/#/R-HSA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose TAS Homo sapiens 33019 R-HSA-70577 https://reactome.org/PathwayBrowser/#/R-HSA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA TAS Homo sapiens 33019 R-HSA-70599 https://reactome.org/PathwayBrowser/#/R-HSA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] TAS Homo sapiens 33019 R-HSA-71732 https://reactome.org/PathwayBrowser/#/R-HSA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate TAS Homo sapiens 33019 R-HSA-71735 https://reactome.org/PathwayBrowser/#/R-HSA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] TAS Homo sapiens 33019 R-HSA-73567 https://reactome.org/PathwayBrowser/#/R-HSA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP TAS Homo sapiens 33019 R-HSA-73666 https://reactome.org/PathwayBrowser/#/R-HSA-73666 dUTP + H2O => dUMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-73792 https://reactome.org/PathwayBrowser/#/R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate TAS Homo sapiens 33019 R-HSA-73815 https://reactome.org/PathwayBrowser/#/R-HSA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate TAS Homo sapiens 33019 R-HSA-73932 https://reactome.org/PathwayBrowser/#/R-HSA-73932 Resynthesis of excised residue by POLB TAS Homo sapiens 33019 R-HSA-74213 https://reactome.org/PathwayBrowser/#/R-HSA-74213 APRT catalyzes the conversion of adenine to AMP TAS Homo sapiens 33019 R-HSA-74215 https://reactome.org/PathwayBrowser/#/R-HSA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 33019 R-HSA-74885 https://reactome.org/PathwayBrowser/#/R-HSA-74885 GUCYs converts GTP to cGMP TAS Homo sapiens 33019 R-HSA-75850 https://reactome.org/PathwayBrowser/#/R-HSA-75850 Addition of the third nucleotide on the nascent transcript TAS Homo sapiens 33019 R-HSA-75864 https://reactome.org/PathwayBrowser/#/R-HSA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released TAS Homo sapiens 33019 R-HSA-75869 https://reactome.org/PathwayBrowser/#/R-HSA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition TAS Homo sapiens 33019 R-HSA-75873 https://reactome.org/PathwayBrowser/#/R-HSA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript TAS Homo sapiens 33019 R-HSA-76576 https://reactome.org/PathwayBrowser/#/R-HSA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition TAS Homo sapiens 33019 R-HSA-8852128 https://reactome.org/PathwayBrowser/#/R-HSA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm TAS Homo sapiens 33019 R-HSA-8852131 https://reactome.org/PathwayBrowser/#/R-HSA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus TAS Homo sapiens 33019 R-HSA-8852132 https://reactome.org/PathwayBrowser/#/R-HSA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol TAS Homo sapiens 33019 R-HSA-8852134 https://reactome.org/PathwayBrowser/#/R-HSA-8852134 UBA1 adenylates ubiquitin in the cytosol TAS Homo sapiens 33019 R-HSA-8865050 https://reactome.org/PathwayBrowser/#/R-HSA-8865050 Ub-Cys625-UBA6 adenylates ubiquitin in the cytosol IEA Homo sapiens 33019 R-HSA-8865090 https://reactome.org/PathwayBrowser/#/R-HSA-8865090 UBA6 adenylates ubiquitin in the cytosol IEA Homo sapiens 33019 R-HSA-8870469 https://reactome.org/PathwayBrowser/#/R-HSA-8870469 RGGT geranylgeranylates RAB proteins TAS Homo sapiens 33019 R-HSA-8875013 https://reactome.org/PathwayBrowser/#/R-HSA-8875013 ACSM3,ACSM6 ligate CoA to BUT IEA Homo sapiens 33019 R-HSA-8875071 https://reactome.org/PathwayBrowser/#/R-HSA-8875071 ACSS3 ligates CoA to CH3COO- TAS Homo sapiens 33019 R-HSA-8875077 https://reactome.org/PathwayBrowser/#/R-HSA-8875077 SLC27A3 ligates CoA-SH to VLCFA IEA Homo sapiens 33019 R-HSA-8939959 https://reactome.org/PathwayBrowser/#/R-HSA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ TAS Homo sapiens 33019 R-HSA-8941312 https://reactome.org/PathwayBrowser/#/R-HSA-8941312 TUT4,TUT7 oligouridylate mRNA IEA Homo sapiens 33019 R-HSA-8951648 https://reactome.org/PathwayBrowser/#/R-HSA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 TAS Homo sapiens 33019 R-HSA-8951656 https://reactome.org/PathwayBrowser/#/R-HSA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 TAS Homo sapiens 33019 R-HSA-8983680 https://reactome.org/PathwayBrowser/#/R-HSA-8983680 OAS1 produces oligoadenylates TAS Homo sapiens 33019 R-HSA-8985091 https://reactome.org/PathwayBrowser/#/R-HSA-8985091 OAS3 produces oligoadenylates TAS Homo sapiens 33019 R-HSA-8985104 https://reactome.org/PathwayBrowser/#/R-HSA-8985104 OAS2 produces oligoadenylates TAS Homo sapiens 33019 R-HSA-9008822 https://reactome.org/PathwayBrowser/#/R-HSA-9008822 PPM1D dephosphorylates RUNX2 TAS Homo sapiens 33019 R-HSA-947531 https://reactome.org/PathwayBrowser/#/R-HSA-947531 Molybdenum ion transfer onto molybdopterin TAS Homo sapiens 33019 R-HSA-947535 https://reactome.org/PathwayBrowser/#/R-HSA-947535 Cyclisation of GTP to precursor Z TAS Homo sapiens 33019 R-HSA-947538 https://reactome.org/PathwayBrowser/#/R-HSA-947538 Transfer of sulfur from MOCS3-S-S onto MOCS2A TAS Homo sapiens 33019 R-HSA-9613490 https://reactome.org/PathwayBrowser/#/R-HSA-9613490 Unwinding of DNA for the nascent HIV-1 transcript: Second Transition IEA Homo sapiens 33019 R-HSA-9613494 https://reactome.org/PathwayBrowser/#/R-HSA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition TAS Homo sapiens 33019 R-HSA-9613497 https://reactome.org/PathwayBrowser/#/R-HSA-9613497 Unwinding DNA for the nascent transcript TAS Homo sapiens 33019 R-HSA-9613498 https://reactome.org/PathwayBrowser/#/R-HSA-9613498 Unwinding of DNA for the nascent HIV-1 transcript IEA Homo sapiens 33019 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 33019 R-HSA-9681651 https://reactome.org/PathwayBrowser/#/R-HSA-9681651 nsp8 generates RNA primers TAS Homo sapiens 33019 R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 33019 R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 33019 R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 33019 R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 33019 R-HSA-9684016 https://reactome.org/PathwayBrowser/#/R-HSA-9684016 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 33019 R-HSA-9684017 https://reactome.org/PathwayBrowser/#/R-HSA-9684017 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 33019 R-HSA-9684018 https://reactome.org/PathwayBrowser/#/R-HSA-9684018 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 33019 R-HSA-9685519 https://reactome.org/PathwayBrowser/#/R-HSA-9685519 Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) TAS Homo sapiens 33019 R-HSA-9685639 https://reactome.org/PathwayBrowser/#/R-HSA-9685639 Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching TAS Homo sapiens 33019 R-HSA-9685681 https://reactome.org/PathwayBrowser/#/R-HSA-9685681 Synthesis of SARS-CoV-1 plus strand subgenomic mRNAs TAS Homo sapiens 33019 R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 33019 R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 33019 R-HSA-9694344 https://reactome.org/PathwayBrowser/#/R-HSA-9694344 Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching IEA Homo sapiens 33019 R-HSA-9694471 https://reactome.org/PathwayBrowser/#/R-HSA-9694471 Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) TAS Homo sapiens 33019 R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 33019 R-HSA-9694506 https://reactome.org/PathwayBrowser/#/R-HSA-9694506 Synthesis of SARS-CoV-2 plus strand subgenomic mRNAs TAS Homo sapiens 33019 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 33019 R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 33019 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 33019 R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 33019 R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 33019 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 33019 R-HSA-9697084 https://reactome.org/PathwayBrowser/#/R-HSA-9697084 Defective rpoB in Mtb RNAP transcribes RNA polyanion TAS Homo sapiens 33019 R-HSA-9697085 https://reactome.org/PathwayBrowser/#/R-HSA-9697085 RNAP transcribes Mtb RNA polyanion TAS Homo sapiens 33019 R-HSA-9717830 https://reactome.org/PathwayBrowser/#/R-HSA-9717830 GGPS1 hexamer transfers IPPP to GPP TAS Homo sapiens 33019 R-HSA-9717834 https://reactome.org/PathwayBrowser/#/R-HSA-9717834 GGPS1 hexamer transfers IPPP to DMAPP TAS Homo sapiens 33019 R-HSA-9731228 https://reactome.org/PathwayBrowser/#/R-HSA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP TAS Homo sapiens 33019 R-HSA-9731590 https://reactome.org/PathwayBrowser/#/R-HSA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP TAS Homo sapiens 33019 R-HSA-9731613 https://reactome.org/PathwayBrowser/#/R-HSA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP TAS Homo sapiens 33019 R-HSA-9731632 https://reactome.org/PathwayBrowser/#/R-HSA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP TAS Homo sapiens 33019 R-HSA-9734535 https://reactome.org/PathwayBrowser/#/R-HSA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA TAS Homo sapiens 33019 R-HSA-9748951 https://reactome.org/PathwayBrowser/#/R-HSA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP TAS Homo sapiens 33019 R-HSA-9748957 https://reactome.org/PathwayBrowser/#/R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP TAS Homo sapiens 33019 R-HSA-9749971 https://reactome.org/PathwayBrowser/#/R-HSA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA TAS Homo sapiens 33019 R-HSA-9750555 https://reactome.org/PathwayBrowser/#/R-HSA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP TAS Homo sapiens 33019 R-HSA-9755030 https://reactome.org/PathwayBrowser/#/R-HSA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP TAS Homo sapiens 33019 R-HSA-9760094 https://reactome.org/PathwayBrowser/#/R-HSA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer TAS Homo sapiens 33019 R-HSA-9765952 https://reactome.org/PathwayBrowser/#/R-HSA-9765952 nsp12 guanylates nsp7 TAS Homo sapiens 33019 R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 33019 R-HSA-9830848 https://reactome.org/PathwayBrowser/#/R-HSA-9830848 L protein acts as a cap N7 methyltransferase to modify RSV mRNAs TAS Homo sapiens 33019 R-HSA-983140 https://reactome.org/PathwayBrowser/#/R-HSA-983140 Transfer of Ub from E2 to substrate and release of E2 TAS Homo sapiens 33019 R-HSA-983153 https://reactome.org/PathwayBrowser/#/R-HSA-983153 E1 mediated ubiquitin activation TAS Homo sapiens 33019 R-HSA-983156 https://reactome.org/PathwayBrowser/#/R-HSA-983156 Polyubiquitination of substrate TAS Homo sapiens 33019 R-HSA-9833031 https://reactome.org/PathwayBrowser/#/R-HSA-9833031 Polyadenylation of respiratory syncytial virus subgenomic positive-sense mRNAs TAS Homo sapiens 33019 R-HSA-9833973 https://reactome.org/PathwayBrowser/#/R-HSA-9833973 ISGylation of PKR TAS Homo sapiens 33019 R-HSA-9837231 https://reactome.org/PathwayBrowser/#/R-HSA-9837231 ISGylation of BECN1 TAS Homo sapiens 33019 R-MMU-110311 https://reactome.org/PathwayBrowser/#/R-MMU-110311 POLZ extends translesion synthesis IEA Mus musculus 33019 R-MMU-110317 https://reactome.org/PathwayBrowser/#/R-MMU-110317 Insertion of correct bases opposite the lesion by POLH IEA Mus musculus 33019 R-MMU-110319 https://reactome.org/PathwayBrowser/#/R-MMU-110319 Elongation by POLH IEA Mus musculus 33019 R-MMU-110368 https://reactome.org/PathwayBrowser/#/R-MMU-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Mus musculus 33019 R-MMU-111253 https://reactome.org/PathwayBrowser/#/R-MMU-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Mus musculus 33019 R-MMU-111264 https://reactome.org/PathwayBrowser/#/R-MMU-111264 Addition of nucleotides between position +11 and +30 IEA Mus musculus 33019 R-MMU-111930 https://reactome.org/PathwayBrowser/#/R-MMU-111930 Adenylate cyclase produces cAMP IEA Mus musculus 33019 R-MMU-1169394 https://reactome.org/PathwayBrowser/#/R-MMU-1169394 ISGylation of IRF3 IEA Mus musculus 33019 R-MMU-1169397 https://reactome.org/PathwayBrowser/#/R-MMU-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Mus musculus 33019 R-MMU-1169398 https://reactome.org/PathwayBrowser/#/R-MMU-1169398 ISGylation of host protein filamin B IEA Mus musculus 33019 R-MMU-1169402 https://reactome.org/PathwayBrowser/#/R-MMU-1169402 ISGylation of E2 conjugating enzymes IEA Mus musculus 33019 R-MMU-1169405 https://reactome.org/PathwayBrowser/#/R-MMU-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Mus musculus 33019 R-MMU-1169406 https://reactome.org/PathwayBrowser/#/R-MMU-1169406 ISGylation of host proteins IEA Mus musculus 33019 R-MMU-1483081 https://reactome.org/PathwayBrowser/#/R-MMU-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Mus musculus 33019 R-MMU-1483121 https://reactome.org/PathwayBrowser/#/R-MMU-1483121 PA is converted to CDP-DAG by CDS1 IEA Mus musculus 33019 R-MMU-1483165 https://reactome.org/PathwayBrowser/#/R-MMU-1483165 PA is converted to CDP-DAG by CDS2 IEA Mus musculus 33019 R-MMU-1483190 https://reactome.org/PathwayBrowser/#/R-MMU-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Mus musculus 33019 R-MMU-159425 https://reactome.org/PathwayBrowser/#/R-MMU-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 33019 R-MMU-159443 https://reactome.org/PathwayBrowser/#/R-MMU-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Mus musculus 33019 R-MMU-159567 https://reactome.org/PathwayBrowser/#/R-MMU-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Mus musculus 33019 R-MMU-170676 https://reactome.org/PathwayBrowser/#/R-MMU-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Mus musculus 33019 R-MMU-174124 https://reactome.org/PathwayBrowser/#/R-MMU-174124 Dephosphorylation of phospho-Cdh1 IEA Mus musculus 33019 R-MMU-174391 https://reactome.org/PathwayBrowser/#/R-MMU-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Mus musculus 33019 R-MMU-174392 https://reactome.org/PathwayBrowser/#/R-MMU-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Mus musculus 33019 R-MMU-177157 https://reactome.org/PathwayBrowser/#/R-MMU-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Mus musculus 33019 R-MMU-191303 https://reactome.org/PathwayBrowser/#/R-MMU-191303 FDPS dimer transfers IPPP to GPP IEA Mus musculus 33019 R-MMU-191322 https://reactome.org/PathwayBrowser/#/R-MMU-191322 FDPS dimer transfers IPPP to DMAPP IEA Mus musculus 33019 R-MMU-191402 https://reactome.org/PathwayBrowser/#/R-MMU-191402 Reduction of presqualene diphosphate to form squalene IEA Mus musculus 33019 R-MMU-191405 https://reactome.org/PathwayBrowser/#/R-MMU-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Mus musculus 33019 R-MMU-192137 https://reactome.org/PathwayBrowser/#/R-MMU-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 33019 R-MMU-193401 https://reactome.org/PathwayBrowser/#/R-MMU-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 33019 R-MMU-193407 https://reactome.org/PathwayBrowser/#/R-MMU-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 33019 R-MMU-193424 https://reactome.org/PathwayBrowser/#/R-MMU-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 33019 R-MMU-193711 https://reactome.org/PathwayBrowser/#/R-MMU-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 33019 R-MMU-193727 https://reactome.org/PathwayBrowser/#/R-MMU-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 33019 R-MMU-193743 https://reactome.org/PathwayBrowser/#/R-MMU-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 33019 R-MMU-193766 https://reactome.org/PathwayBrowser/#/R-MMU-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 33019 R-MMU-196753 https://reactome.org/PathwayBrowser/#/R-MMU-196753 2xPPCS ligates PPanK with Cys IEA Mus musculus 33019 R-MMU-196754 https://reactome.org/PathwayBrowser/#/R-MMU-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Mus musculus 33019 R-MMU-196929 https://reactome.org/PathwayBrowser/#/R-MMU-196929 FLAD1 phosphorylates FMN IEA Mus musculus 33019 R-MMU-197186 https://reactome.org/PathwayBrowser/#/R-MMU-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Mus musculus 33019 R-MMU-197235 https://reactome.org/PathwayBrowser/#/R-MMU-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 33019 R-MMU-197250 https://reactome.org/PathwayBrowser/#/R-MMU-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Mus musculus 33019 R-MMU-197268 https://reactome.org/PathwayBrowser/#/R-MMU-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Mus musculus 33019 R-MMU-197271 https://reactome.org/PathwayBrowser/#/R-MMU-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Mus musculus 33019 R-MMU-200474 https://reactome.org/PathwayBrowser/#/R-MMU-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 33019 R-MMU-200512 https://reactome.org/PathwayBrowser/#/R-MMU-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 33019 R-MMU-201035 https://reactome.org/PathwayBrowser/#/R-MMU-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Mus musculus 33019 R-MMU-2046085 https://reactome.org/PathwayBrowser/#/R-MMU-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Mus musculus 33019 R-MMU-2046098 https://reactome.org/PathwayBrowser/#/R-MMU-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Mus musculus 33019 R-MMU-2162192 https://reactome.org/PathwayBrowser/#/R-MMU-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Mus musculus 33019 R-MMU-2162253 https://reactome.org/PathwayBrowser/#/R-MMU-2162253 PDSS1,2 ligates FPP to IPPP IEA Mus musculus 33019 R-MMU-2395818 https://reactome.org/PathwayBrowser/#/R-MMU-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Mus musculus 33019 R-MMU-2395849 https://reactome.org/PathwayBrowser/#/R-MMU-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 33019 R-MMU-2395869 https://reactome.org/PathwayBrowser/#/R-MMU-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 33019 R-MMU-2395872 https://reactome.org/PathwayBrowser/#/R-MMU-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Mus musculus 33019 R-MMU-2408551 https://reactome.org/PathwayBrowser/#/R-MMU-2408551 SeMet is converted to AdoSeMet by MAT IEA Mus musculus 33019 R-MMU-2509827 https://reactome.org/PathwayBrowser/#/R-MMU-2509827 ITPA hydrolyses ITP to IMP IEA Mus musculus 33019 R-MMU-2509831 https://reactome.org/PathwayBrowser/#/R-MMU-2509831 ITPA hydrolyses XTP to XMP IEA Mus musculus 33019 R-MMU-2509838 https://reactome.org/PathwayBrowser/#/R-MMU-2509838 ITPA hydrolyses dITP to dIMP IEA Mus musculus 33019 R-MMU-2530501 https://reactome.org/PathwayBrowser/#/R-MMU-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Mus musculus 33019 R-MMU-2730904 https://reactome.org/PathwayBrowser/#/R-MMU-2730904 Auto-ubiquitination of TRAF6 IEA Mus musculus 33019 R-MMU-2990833 https://reactome.org/PathwayBrowser/#/R-MMU-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Mus musculus 33019 R-MMU-2993447 https://reactome.org/PathwayBrowser/#/R-MMU-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Mus musculus 33019 R-MMU-2993799 https://reactome.org/PathwayBrowser/#/R-MMU-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Mus musculus 33019 R-MMU-2993802 https://reactome.org/PathwayBrowser/#/R-MMU-2993802 HLCS biotinylates PC:Mn2+ IEA Mus musculus 33019 R-MMU-2993814 https://reactome.org/PathwayBrowser/#/R-MMU-2993814 HLCS biotinylates ACACA:Mn2+ IEA Mus musculus 33019 R-MMU-2995330 https://reactome.org/PathwayBrowser/#/R-MMU-2995330 COX10 transforms heme to heme O IEA Mus musculus 33019 R-MMU-389622 https://reactome.org/PathwayBrowser/#/R-MMU-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 33019 R-MMU-389632 https://reactome.org/PathwayBrowser/#/R-MMU-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 33019 R-MMU-389758 https://reactome.org/PathwayBrowser/#/R-MMU-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Mus musculus 33019 R-MMU-392513 https://reactome.org/PathwayBrowser/#/R-MMU-392513 Rap1 signal termination by Rap1GAPs IEA Mus musculus 33019 R-MMU-4084982 https://reactome.org/PathwayBrowser/#/R-MMU-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Mus musculus 33019 R-MMU-4167511 https://reactome.org/PathwayBrowser/#/R-MMU-4167511 HLCS biotinylates ACACB IEA Mus musculus 33019 R-MMU-434382 https://reactome.org/PathwayBrowser/#/R-MMU-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Mus musculus 33019 R-MMU-446204 https://reactome.org/PathwayBrowser/#/R-MMU-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Mus musculus 33019 R-MMU-449911 https://reactome.org/PathwayBrowser/#/R-MMU-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Mus musculus 33019 R-MMU-449937 https://reactome.org/PathwayBrowser/#/R-MMU-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Mus musculus 33019 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 33019 R-MMU-5226964 https://reactome.org/PathwayBrowser/#/R-MMU-5226964 ANKH transports PPi from cytosol to extracellular region IEA Mus musculus 33019 R-MMU-5358475 https://reactome.org/PathwayBrowser/#/R-MMU-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Mus musculus 33019 R-MMU-5358592 https://reactome.org/PathwayBrowser/#/R-MMU-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Mus musculus 33019 R-MMU-548843 https://reactome.org/PathwayBrowser/#/R-MMU-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Mus musculus 33019 R-MMU-5603114 https://reactome.org/PathwayBrowser/#/R-MMU-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Mus musculus 33019 R-MMU-5607756 https://reactome.org/PathwayBrowser/#/R-MMU-5607756 TRAF6 oligomer autoubiquitinates IEA Mus musculus 33019 R-MMU-5607757 https://reactome.org/PathwayBrowser/#/R-MMU-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 IEA Mus musculus 33019 R-MMU-5610727 https://reactome.org/PathwayBrowser/#/R-MMU-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Mus musculus 33019 R-MMU-5649723 https://reactome.org/PathwayBrowser/#/R-MMU-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Mus musculus 33019 R-MMU-5649883 https://reactome.org/PathwayBrowser/#/R-MMU-5649883 POLB-mediated DNA strand displacement synthesis IEA Mus musculus 33019 R-MMU-5655892 https://reactome.org/PathwayBrowser/#/R-MMU-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Mus musculus 33019 R-MMU-5655965 https://reactome.org/PathwayBrowser/#/R-MMU-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Mus musculus 33019 R-MMU-5656148 https://reactome.org/PathwayBrowser/#/R-MMU-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Mus musculus 33019 R-MMU-5656158 https://reactome.org/PathwayBrowser/#/R-MMU-5656158 POLZ elongates POLI-incorporated dNMP IEA Mus musculus 33019 R-MMU-5687360 https://reactome.org/PathwayBrowser/#/R-MMU-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Mus musculus 33019 R-MMU-5687640 https://reactome.org/PathwayBrowser/#/R-MMU-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Mus musculus 33019 R-MMU-5691001 https://reactome.org/PathwayBrowser/#/R-MMU-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Mus musculus 33019 R-MMU-5693593 https://reactome.org/PathwayBrowser/#/R-MMU-5693593 D-loop extension by DNA polymerases IEA Mus musculus 33019 R-MMU-5694494 https://reactome.org/PathwayBrowser/#/R-MMU-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Mus musculus 33019 R-MMU-5695957 https://reactome.org/PathwayBrowser/#/R-MMU-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Mus musculus 33019 R-MMU-5696004 https://reactome.org/PathwayBrowser/#/R-MMU-5696004 ACSF2 ligates CoA-SH to MCFA IEA Mus musculus 33019 R-MMU-5696007 https://reactome.org/PathwayBrowser/#/R-MMU-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Mus musculus 33019 R-MMU-6781824 https://reactome.org/PathwayBrowser/#/R-MMU-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Mus musculus 33019 R-MMU-6782208 https://reactome.org/PathwayBrowser/#/R-MMU-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Mus musculus 33019 R-MMU-6786166 https://reactome.org/PathwayBrowser/#/R-MMU-6786166 Translesion synthesis across unhooked ICL by POLN IEA Mus musculus 33019 R-MMU-6786295 https://reactome.org/PathwayBrowser/#/R-MMU-6786295 Dctpp1 hydrolyses 5idCTP TAS Mus musculus 33019 R-MMU-6787533 https://reactome.org/PathwayBrowser/#/R-MMU-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Mus musculus 33019 R-MMU-6788912 https://reactome.org/PathwayBrowser/#/R-MMU-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Mus musculus 33019 R-MMU-6806674 https://reactome.org/PathwayBrowser/#/R-MMU-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Mus musculus 33019 R-MMU-70286 https://reactome.org/PathwayBrowser/#/R-MMU-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Mus musculus 33019 R-MMU-70577 https://reactome.org/PathwayBrowser/#/R-MMU-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Mus musculus 33019 R-MMU-70599 https://reactome.org/PathwayBrowser/#/R-MMU-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Mus musculus 33019 R-MMU-71732 https://reactome.org/PathwayBrowser/#/R-MMU-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Mus musculus 33019 R-MMU-71735 https://reactome.org/PathwayBrowser/#/R-MMU-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Mus musculus 33019 R-MMU-73567 https://reactome.org/PathwayBrowser/#/R-MMU-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Mus musculus 33019 R-MMU-73666 https://reactome.org/PathwayBrowser/#/R-MMU-73666 dUTP + H2O => dUMP + pyrophosphate IEA Mus musculus 33019 R-MMU-73792 https://reactome.org/PathwayBrowser/#/R-MMU-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Mus musculus 33019 R-MMU-73815 https://reactome.org/PathwayBrowser/#/R-MMU-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Mus musculus 33019 R-MMU-73932 https://reactome.org/PathwayBrowser/#/R-MMU-73932 Resynthesis of excised residue by POLB IEA Mus musculus 33019 R-MMU-74213 https://reactome.org/PathwayBrowser/#/R-MMU-74213 APRT catalyzes the conversion of adenine to AMP IEA Mus musculus 33019 R-MMU-74215 https://reactome.org/PathwayBrowser/#/R-MMU-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Mus musculus 33019 R-MMU-74885 https://reactome.org/PathwayBrowser/#/R-MMU-74885 GUCYs converts GTP to cGMP IEA Mus musculus 33019 R-MMU-75850 https://reactome.org/PathwayBrowser/#/R-MMU-75850 Addition of the third nucleotide on the nascent transcript IEA Mus musculus 33019 R-MMU-75864 https://reactome.org/PathwayBrowser/#/R-MMU-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Mus musculus 33019 R-MMU-75869 https://reactome.org/PathwayBrowser/#/R-MMU-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Mus musculus 33019 R-MMU-75873 https://reactome.org/PathwayBrowser/#/R-MMU-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Mus musculus 33019 R-MMU-76576 https://reactome.org/PathwayBrowser/#/R-MMU-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Mus musculus 33019 R-MMU-8852128 https://reactome.org/PathwayBrowser/#/R-MMU-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Mus musculus 33019 R-MMU-8852131 https://reactome.org/PathwayBrowser/#/R-MMU-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Mus musculus 33019 R-MMU-8852132 https://reactome.org/PathwayBrowser/#/R-MMU-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Mus musculus 33019 R-MMU-8852134 https://reactome.org/PathwayBrowser/#/R-MMU-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Mus musculus 33019 R-MMU-8870469 https://reactome.org/PathwayBrowser/#/R-MMU-8870469 RGGT geranylgeranylates RAB proteins IEA Mus musculus 33019 R-MMU-8875039 https://reactome.org/PathwayBrowser/#/R-MMU-8875039 Acsm3 ligates CoA to BUT TAS Mus musculus 33019 R-MMU-8875071 https://reactome.org/PathwayBrowser/#/R-MMU-8875071 ACSS3 ligates CoA to CH3COO- IEA Mus musculus 33019 R-MMU-8875095 https://reactome.org/PathwayBrowser/#/R-MMU-8875095 Slc27a3 ligates CoA to VLCFA TAS Mus musculus 33019 R-MMU-8939959 https://reactome.org/PathwayBrowser/#/R-MMU-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Mus musculus 33019 R-MMU-8951648 https://reactome.org/PathwayBrowser/#/R-MMU-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Mus musculus 33019 R-MMU-8951656 https://reactome.org/PathwayBrowser/#/R-MMU-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Mus musculus 33019 R-MMU-9008822 https://reactome.org/PathwayBrowser/#/R-MMU-9008822 PPM1D dephosphorylates RUNX2 IEA Mus musculus 33019 R-MMU-947531 https://reactome.org/PathwayBrowser/#/R-MMU-947531 Molybdenum ion transfer onto molybdopterin IEA Mus musculus 33019 R-MMU-947535 https://reactome.org/PathwayBrowser/#/R-MMU-947535 Cyclisation of GTP to precursor Z IEA Mus musculus 33019 R-MMU-9613494 https://reactome.org/PathwayBrowser/#/R-MMU-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Mus musculus 33019 R-MMU-9613497 https://reactome.org/PathwayBrowser/#/R-MMU-9613497 Unwinding DNA for the nascent transcript IEA Mus musculus 33019 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 33019 R-MMU-9717830 https://reactome.org/PathwayBrowser/#/R-MMU-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Mus musculus 33019 R-MMU-9717834 https://reactome.org/PathwayBrowser/#/R-MMU-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Mus musculus 33019 R-MMU-9731228 https://reactome.org/PathwayBrowser/#/R-MMU-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Mus musculus 33019 R-MMU-9731590 https://reactome.org/PathwayBrowser/#/R-MMU-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Mus musculus 33019 R-MMU-9731613 https://reactome.org/PathwayBrowser/#/R-MMU-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Mus musculus 33019 R-MMU-9731632 https://reactome.org/PathwayBrowser/#/R-MMU-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Mus musculus 33019 R-MMU-9734535 https://reactome.org/PathwayBrowser/#/R-MMU-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Mus musculus 33019 R-MMU-9748951 https://reactome.org/PathwayBrowser/#/R-MMU-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Mus musculus 33019 R-MMU-9748957 https://reactome.org/PathwayBrowser/#/R-MMU-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Mus musculus 33019 R-MMU-9749971 https://reactome.org/PathwayBrowser/#/R-MMU-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Mus musculus 33019 R-MMU-9750555 https://reactome.org/PathwayBrowser/#/R-MMU-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Mus musculus 33019 R-MMU-9755030 https://reactome.org/PathwayBrowser/#/R-MMU-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Mus musculus 33019 R-MMU-9760094 https://reactome.org/PathwayBrowser/#/R-MMU-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Mus musculus 33019 R-MMU-9820884 https://reactome.org/PathwayBrowser/#/R-MMU-9820884 Tut4,Tut7 oligouridylate mRNA TAS Mus musculus 33019 R-MMU-983140 https://reactome.org/PathwayBrowser/#/R-MMU-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Mus musculus 33019 R-MMU-983153 https://reactome.org/PathwayBrowser/#/R-MMU-983153 E1 mediated ubiquitin activation IEA Mus musculus 33019 R-MMU-983156 https://reactome.org/PathwayBrowser/#/R-MMU-983156 Polyubiquitination of substrate IEA Mus musculus 33019 R-MMU-9833973 https://reactome.org/PathwayBrowser/#/R-MMU-9833973 ISGylation of PKR IEA Mus musculus 33019 R-MTU-879319 https://reactome.org/PathwayBrowser/#/R-MTU-879319 glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol TAS Mycobacterium tuberculosis 33019 R-MTU-936729 https://reactome.org/PathwayBrowser/#/R-MTU-936729 sulfate is activated to APS TAS Mycobacterium tuberculosis 33019 R-MTU-9635480 https://reactome.org/PathwayBrowser/#/R-MTU-9635480 FadD26, FadD28 transfer adenylyl group to a LCFA TAS Mycobacterium tuberculosis 33019 R-PFA-110311 https://reactome.org/PathwayBrowser/#/R-PFA-110311 POLZ extends translesion synthesis IEA Plasmodium falciparum 33019 R-PFA-110317 https://reactome.org/PathwayBrowser/#/R-PFA-110317 Insertion of correct bases opposite the lesion by POLH IEA Plasmodium falciparum 33019 R-PFA-110319 https://reactome.org/PathwayBrowser/#/R-PFA-110319 Elongation by POLH IEA Plasmodium falciparum 33019 R-PFA-110368 https://reactome.org/PathwayBrowser/#/R-PFA-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Plasmodium falciparum 33019 R-PFA-111264 https://reactome.org/PathwayBrowser/#/R-PFA-111264 Addition of nucleotides between position +11 and +30 IEA Plasmodium falciparum 33019 R-PFA-1169397 https://reactome.org/PathwayBrowser/#/R-PFA-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Plasmodium falciparum 33019 R-PFA-1483081 https://reactome.org/PathwayBrowser/#/R-PFA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Plasmodium falciparum 33019 R-PFA-1483121 https://reactome.org/PathwayBrowser/#/R-PFA-1483121 PA is converted to CDP-DAG by CDS1 IEA Plasmodium falciparum 33019 R-PFA-1483165 https://reactome.org/PathwayBrowser/#/R-PFA-1483165 PA is converted to CDP-DAG by CDS2 IEA Plasmodium falciparum 33019 R-PFA-1483190 https://reactome.org/PathwayBrowser/#/R-PFA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Plasmodium falciparum 33019 R-PFA-174391 https://reactome.org/PathwayBrowser/#/R-PFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Plasmodium falciparum 33019 R-PFA-191303 https://reactome.org/PathwayBrowser/#/R-PFA-191303 FDPS dimer transfers IPPP to GPP IEA Plasmodium falciparum 33019 R-PFA-191322 https://reactome.org/PathwayBrowser/#/R-PFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Plasmodium falciparum 33019 R-PFA-196753 https://reactome.org/PathwayBrowser/#/R-PFA-196753 2xPPCS ligates PPanK with Cys IEA Plasmodium falciparum 33019 R-PFA-196929 https://reactome.org/PathwayBrowser/#/R-PFA-196929 FLAD1 phosphorylates FMN IEA Plasmodium falciparum 33019 R-PFA-197186 https://reactome.org/PathwayBrowser/#/R-PFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Plasmodium falciparum 33019 R-PFA-197271 https://reactome.org/PathwayBrowser/#/R-PFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Plasmodium falciparum 33019 R-PFA-201035 https://reactome.org/PathwayBrowser/#/R-PFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Plasmodium falciparum 33019 R-PFA-2046085 https://reactome.org/PathwayBrowser/#/R-PFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Plasmodium falciparum 33019 R-PFA-2046098 https://reactome.org/PathwayBrowser/#/R-PFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Plasmodium falciparum 33019 R-PFA-2162192 https://reactome.org/PathwayBrowser/#/R-PFA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Plasmodium falciparum 33019 R-PFA-2162253 https://reactome.org/PathwayBrowser/#/R-PFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Plasmodium falciparum 33019 R-PFA-2395818 https://reactome.org/PathwayBrowser/#/R-PFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Plasmodium falciparum 33019 R-PFA-2395849 https://reactome.org/PathwayBrowser/#/R-PFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Plasmodium falciparum 33019 R-PFA-2395872 https://reactome.org/PathwayBrowser/#/R-PFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Plasmodium falciparum 33019 R-PFA-2408551 https://reactome.org/PathwayBrowser/#/R-PFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Plasmodium falciparum 33019 R-PFA-2509827 https://reactome.org/PathwayBrowser/#/R-PFA-2509827 ITPA hydrolyses ITP to IMP IEA Plasmodium falciparum 33019 R-PFA-2509831 https://reactome.org/PathwayBrowser/#/R-PFA-2509831 ITPA hydrolyses XTP to XMP IEA Plasmodium falciparum 33019 R-PFA-2509838 https://reactome.org/PathwayBrowser/#/R-PFA-2509838 ITPA hydrolyses dITP to dIMP IEA Plasmodium falciparum 33019 R-PFA-2993814 https://reactome.org/PathwayBrowser/#/R-PFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Plasmodium falciparum 33019 R-PFA-2995330 https://reactome.org/PathwayBrowser/#/R-PFA-2995330 COX10 transforms heme to heme O IEA Plasmodium falciparum 33019 R-PFA-4167511 https://reactome.org/PathwayBrowser/#/R-PFA-4167511 HLCS biotinylates ACACB IEA Plasmodium falciparum 33019 R-PFA-446204 https://reactome.org/PathwayBrowser/#/R-PFA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Plasmodium falciparum 33019 R-PFA-449911 https://reactome.org/PathwayBrowser/#/R-PFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Plasmodium falciparum 33019 R-PFA-449937 https://reactome.org/PathwayBrowser/#/R-PFA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Plasmodium falciparum 33019 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 33019 R-PFA-5358592 https://reactome.org/PathwayBrowser/#/R-PFA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Plasmodium falciparum 33019 R-PFA-5655892 https://reactome.org/PathwayBrowser/#/R-PFA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Plasmodium falciparum 33019 R-PFA-5655965 https://reactome.org/PathwayBrowser/#/R-PFA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Plasmodium falciparum 33019 R-PFA-5656148 https://reactome.org/PathwayBrowser/#/R-PFA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Plasmodium falciparum 33019 R-PFA-5656158 https://reactome.org/PathwayBrowser/#/R-PFA-5656158 POLZ elongates POLI-incorporated dNMP IEA Plasmodium falciparum 33019 R-PFA-5691001 https://reactome.org/PathwayBrowser/#/R-PFA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Plasmodium falciparum 33019 R-PFA-6781824 https://reactome.org/PathwayBrowser/#/R-PFA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Plasmodium falciparum 33019 R-PFA-6782208 https://reactome.org/PathwayBrowser/#/R-PFA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Plasmodium falciparum 33019 R-PFA-70599 https://reactome.org/PathwayBrowser/#/R-PFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Plasmodium falciparum 33019 R-PFA-71732 https://reactome.org/PathwayBrowser/#/R-PFA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Plasmodium falciparum 33019 R-PFA-71735 https://reactome.org/PathwayBrowser/#/R-PFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Plasmodium falciparum 33019 R-PFA-73666 https://reactome.org/PathwayBrowser/#/R-PFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Plasmodium falciparum 33019 R-PFA-73792 https://reactome.org/PathwayBrowser/#/R-PFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Plasmodium falciparum 33019 R-PFA-74215 https://reactome.org/PathwayBrowser/#/R-PFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Plasmodium falciparum 33019 R-PFA-76576 https://reactome.org/PathwayBrowser/#/R-PFA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Plasmodium falciparum 33019 R-PFA-8852128 https://reactome.org/PathwayBrowser/#/R-PFA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Plasmodium falciparum 33019 R-PFA-8852131 https://reactome.org/PathwayBrowser/#/R-PFA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Plasmodium falciparum 33019 R-PFA-8852132 https://reactome.org/PathwayBrowser/#/R-PFA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Plasmodium falciparum 33019 R-PFA-8852134 https://reactome.org/PathwayBrowser/#/R-PFA-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Plasmodium falciparum 33019 R-PFA-8870469 https://reactome.org/PathwayBrowser/#/R-PFA-8870469 RGGT geranylgeranylates RAB proteins IEA Plasmodium falciparum 33019 R-PFA-8951648 https://reactome.org/PathwayBrowser/#/R-PFA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Plasmodium falciparum 33019 R-PFA-8951656 https://reactome.org/PathwayBrowser/#/R-PFA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Plasmodium falciparum 33019 R-PFA-9731228 https://reactome.org/PathwayBrowser/#/R-PFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Plasmodium falciparum 33019 R-PFA-9731590 https://reactome.org/PathwayBrowser/#/R-PFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Plasmodium falciparum 33019 R-PFA-9731613 https://reactome.org/PathwayBrowser/#/R-PFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Plasmodium falciparum 33019 R-PFA-9731632 https://reactome.org/PathwayBrowser/#/R-PFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Plasmodium falciparum 33019 R-PFA-9748951 https://reactome.org/PathwayBrowser/#/R-PFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Plasmodium falciparum 33019 R-PFA-9748957 https://reactome.org/PathwayBrowser/#/R-PFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Plasmodium falciparum 33019 R-PFA-9755030 https://reactome.org/PathwayBrowser/#/R-PFA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Plasmodium falciparum 33019 R-PFA-983140 https://reactome.org/PathwayBrowser/#/R-PFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Plasmodium falciparum 33019 R-PFA-983153 https://reactome.org/PathwayBrowser/#/R-PFA-983153 E1 mediated ubiquitin activation IEA Plasmodium falciparum 33019 R-PFA-983156 https://reactome.org/PathwayBrowser/#/R-PFA-983156 Polyubiquitination of substrate IEA Plasmodium falciparum 33019 R-RNO-110311 https://reactome.org/PathwayBrowser/#/R-RNO-110311 POLZ extends translesion synthesis IEA Rattus norvegicus 33019 R-RNO-110317 https://reactome.org/PathwayBrowser/#/R-RNO-110317 Insertion of correct bases opposite the lesion by POLH IEA Rattus norvegicus 33019 R-RNO-110319 https://reactome.org/PathwayBrowser/#/R-RNO-110319 Elongation by POLH IEA Rattus norvegicus 33019 R-RNO-110368 https://reactome.org/PathwayBrowser/#/R-RNO-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Rattus norvegicus 33019 R-RNO-111253 https://reactome.org/PathwayBrowser/#/R-RNO-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Rattus norvegicus 33019 R-RNO-111264 https://reactome.org/PathwayBrowser/#/R-RNO-111264 Addition of nucleotides between position +11 and +30 IEA Rattus norvegicus 33019 R-RNO-111930 https://reactome.org/PathwayBrowser/#/R-RNO-111930 Adenylate cyclase produces cAMP IEA Rattus norvegicus 33019 R-RNO-1169394 https://reactome.org/PathwayBrowser/#/R-RNO-1169394 ISGylation of IRF3 IEA Rattus norvegicus 33019 R-RNO-1169397 https://reactome.org/PathwayBrowser/#/R-RNO-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Rattus norvegicus 33019 R-RNO-1169398 https://reactome.org/PathwayBrowser/#/R-RNO-1169398 ISGylation of host protein filamin B IEA Rattus norvegicus 33019 R-RNO-1169402 https://reactome.org/PathwayBrowser/#/R-RNO-1169402 ISGylation of E2 conjugating enzymes IEA Rattus norvegicus 33019 R-RNO-1169405 https://reactome.org/PathwayBrowser/#/R-RNO-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Rattus norvegicus 33019 R-RNO-1169406 https://reactome.org/PathwayBrowser/#/R-RNO-1169406 ISGylation of host proteins IEA Rattus norvegicus 33019 R-RNO-1483081 https://reactome.org/PathwayBrowser/#/R-RNO-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Rattus norvegicus 33019 R-RNO-1483121 https://reactome.org/PathwayBrowser/#/R-RNO-1483121 PA is converted to CDP-DAG by CDS1 IEA Rattus norvegicus 33019 R-RNO-1483165 https://reactome.org/PathwayBrowser/#/R-RNO-1483165 PA is converted to CDP-DAG by CDS2 IEA Rattus norvegicus 33019 R-RNO-1483190 https://reactome.org/PathwayBrowser/#/R-RNO-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Rattus norvegicus 33019 R-RNO-159425 https://reactome.org/PathwayBrowser/#/R-RNO-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 33019 R-RNO-159443 https://reactome.org/PathwayBrowser/#/R-RNO-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 33019 R-RNO-159567 https://reactome.org/PathwayBrowser/#/R-RNO-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Rattus norvegicus 33019 R-RNO-170676 https://reactome.org/PathwayBrowser/#/R-RNO-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Rattus norvegicus 33019 R-RNO-174124 https://reactome.org/PathwayBrowser/#/R-RNO-174124 Dephosphorylation of phospho-Cdh1 IEA Rattus norvegicus 33019 R-RNO-174391 https://reactome.org/PathwayBrowser/#/R-RNO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Rattus norvegicus 33019 R-RNO-174392 https://reactome.org/PathwayBrowser/#/R-RNO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Rattus norvegicus 33019 R-RNO-177157 https://reactome.org/PathwayBrowser/#/R-RNO-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 33019 R-RNO-191303 https://reactome.org/PathwayBrowser/#/R-RNO-191303 FDPS dimer transfers IPPP to GPP IEA Rattus norvegicus 33019 R-RNO-191322 https://reactome.org/PathwayBrowser/#/R-RNO-191322 FDPS dimer transfers IPPP to DMAPP IEA Rattus norvegicus 33019 R-RNO-191402 https://reactome.org/PathwayBrowser/#/R-RNO-191402 Reduction of presqualene diphosphate to form squalene IEA Rattus norvegicus 33019 R-RNO-191405 https://reactome.org/PathwayBrowser/#/R-RNO-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Rattus norvegicus 33019 R-RNO-192137 https://reactome.org/PathwayBrowser/#/R-RNO-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 33019 R-RNO-193401 https://reactome.org/PathwayBrowser/#/R-RNO-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 33019 R-RNO-193407 https://reactome.org/PathwayBrowser/#/R-RNO-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 33019 R-RNO-193424 https://reactome.org/PathwayBrowser/#/R-RNO-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 33019 R-RNO-193711 https://reactome.org/PathwayBrowser/#/R-RNO-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 33019 R-RNO-193727 https://reactome.org/PathwayBrowser/#/R-RNO-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 33019 R-RNO-193743 https://reactome.org/PathwayBrowser/#/R-RNO-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 33019 R-RNO-193766 https://reactome.org/PathwayBrowser/#/R-RNO-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 33019 R-RNO-196753 https://reactome.org/PathwayBrowser/#/R-RNO-196753 2xPPCS ligates PPanK with Cys IEA Rattus norvegicus 33019 R-RNO-196754 https://reactome.org/PathwayBrowser/#/R-RNO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Rattus norvegicus 33019 R-RNO-196929 https://reactome.org/PathwayBrowser/#/R-RNO-196929 FLAD1 phosphorylates FMN IEA Rattus norvegicus 33019 R-RNO-197186 https://reactome.org/PathwayBrowser/#/R-RNO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Rattus norvegicus 33019 R-RNO-197235 https://reactome.org/PathwayBrowser/#/R-RNO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 33019 R-RNO-197250 https://reactome.org/PathwayBrowser/#/R-RNO-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Rattus norvegicus 33019 R-RNO-197268 https://reactome.org/PathwayBrowser/#/R-RNO-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Rattus norvegicus 33019 R-RNO-197271 https://reactome.org/PathwayBrowser/#/R-RNO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Rattus norvegicus 33019 R-RNO-200474 https://reactome.org/PathwayBrowser/#/R-RNO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 33019 R-RNO-200512 https://reactome.org/PathwayBrowser/#/R-RNO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 33019 R-RNO-201035 https://reactome.org/PathwayBrowser/#/R-RNO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Rattus norvegicus 33019 R-RNO-2046085 https://reactome.org/PathwayBrowser/#/R-RNO-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Rattus norvegicus 33019 R-RNO-2046098 https://reactome.org/PathwayBrowser/#/R-RNO-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Rattus norvegicus 33019 R-RNO-2162192 https://reactome.org/PathwayBrowser/#/R-RNO-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Rattus norvegicus 33019 R-RNO-2162253 https://reactome.org/PathwayBrowser/#/R-RNO-2162253 PDSS1,2 ligates FPP to IPPP IEA Rattus norvegicus 33019 R-RNO-2395818 https://reactome.org/PathwayBrowser/#/R-RNO-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Rattus norvegicus 33019 R-RNO-2395849 https://reactome.org/PathwayBrowser/#/R-RNO-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 33019 R-RNO-2395869 https://reactome.org/PathwayBrowser/#/R-RNO-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 33019 R-RNO-2395872 https://reactome.org/PathwayBrowser/#/R-RNO-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Rattus norvegicus 33019 R-RNO-2408504 https://reactome.org/PathwayBrowser/#/R-RNO-2408504 H2SeO4 is converted to APSe by PAPSS1,2 TAS Rattus norvegicus 33019 R-RNO-2408551 https://reactome.org/PathwayBrowser/#/R-RNO-2408551 SeMet is converted to AdoSeMet by MAT IEA Rattus norvegicus 33019 R-RNO-2509827 https://reactome.org/PathwayBrowser/#/R-RNO-2509827 ITPA hydrolyses ITP to IMP IEA Rattus norvegicus 33019 R-RNO-2509831 https://reactome.org/PathwayBrowser/#/R-RNO-2509831 ITPA hydrolyses XTP to XMP IEA Rattus norvegicus 33019 R-RNO-2509838 https://reactome.org/PathwayBrowser/#/R-RNO-2509838 ITPA hydrolyses dITP to dIMP IEA Rattus norvegicus 33019 R-RNO-2530501 https://reactome.org/PathwayBrowser/#/R-RNO-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Rattus norvegicus 33019 R-RNO-2990833 https://reactome.org/PathwayBrowser/#/R-RNO-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Rattus norvegicus 33019 R-RNO-2993447 https://reactome.org/PathwayBrowser/#/R-RNO-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Rattus norvegicus 33019 R-RNO-2993799 https://reactome.org/PathwayBrowser/#/R-RNO-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Rattus norvegicus 33019 R-RNO-2993802 https://reactome.org/PathwayBrowser/#/R-RNO-2993802 HLCS biotinylates PC:Mn2+ IEA Rattus norvegicus 33019 R-RNO-2993814 https://reactome.org/PathwayBrowser/#/R-RNO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Rattus norvegicus 33019 R-RNO-2995330 https://reactome.org/PathwayBrowser/#/R-RNO-2995330 COX10 transforms heme to heme O IEA Rattus norvegicus 33019 R-RNO-389622 https://reactome.org/PathwayBrowser/#/R-RNO-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 33019 R-RNO-389632 https://reactome.org/PathwayBrowser/#/R-RNO-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 33019 R-RNO-389758 https://reactome.org/PathwayBrowser/#/R-RNO-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Rattus norvegicus 33019 R-RNO-392513 https://reactome.org/PathwayBrowser/#/R-RNO-392513 Rap1 signal termination by Rap1GAPs IEA Rattus norvegicus 33019 R-RNO-4084982 https://reactome.org/PathwayBrowser/#/R-RNO-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Rattus norvegicus 33019 R-RNO-4167511 https://reactome.org/PathwayBrowser/#/R-RNO-4167511 HLCS biotinylates ACACB IEA Rattus norvegicus 33019 R-RNO-427288 https://reactome.org/PathwayBrowser/#/R-RNO-427288 Soluble guanylate cyclase converts GTP to cGMP TAS Rattus norvegicus 33019 R-RNO-434382 https://reactome.org/PathwayBrowser/#/R-RNO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Rattus norvegicus 33019 R-RNO-446204 https://reactome.org/PathwayBrowser/#/R-RNO-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Rattus norvegicus 33019 R-RNO-449911 https://reactome.org/PathwayBrowser/#/R-RNO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Rattus norvegicus 33019 R-RNO-449937 https://reactome.org/PathwayBrowser/#/R-RNO-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Rattus norvegicus 33019 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 33019 R-RNO-5226964 https://reactome.org/PathwayBrowser/#/R-RNO-5226964 ANKH transports PPi from cytosol to extracellular region IEA Rattus norvegicus 33019 R-RNO-5358475 https://reactome.org/PathwayBrowser/#/R-RNO-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Rattus norvegicus 33019 R-RNO-5358592 https://reactome.org/PathwayBrowser/#/R-RNO-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Rattus norvegicus 33019 R-RNO-548843 https://reactome.org/PathwayBrowser/#/R-RNO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Rattus norvegicus 33019 R-RNO-5603114 https://reactome.org/PathwayBrowser/#/R-RNO-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Rattus norvegicus 33019 R-RNO-5610727 https://reactome.org/PathwayBrowser/#/R-RNO-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Rattus norvegicus 33019 R-RNO-5649723 https://reactome.org/PathwayBrowser/#/R-RNO-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Rattus norvegicus 33019 R-RNO-5649883 https://reactome.org/PathwayBrowser/#/R-RNO-5649883 POLB-mediated DNA strand displacement synthesis IEA Rattus norvegicus 33019 R-RNO-5655892 https://reactome.org/PathwayBrowser/#/R-RNO-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Rattus norvegicus 33019 R-RNO-5655965 https://reactome.org/PathwayBrowser/#/R-RNO-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Rattus norvegicus 33019 R-RNO-5656148 https://reactome.org/PathwayBrowser/#/R-RNO-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Rattus norvegicus 33019 R-RNO-5656158 https://reactome.org/PathwayBrowser/#/R-RNO-5656158 POLZ elongates POLI-incorporated dNMP IEA Rattus norvegicus 33019 R-RNO-5687360 https://reactome.org/PathwayBrowser/#/R-RNO-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Rattus norvegicus 33019 R-RNO-5687640 https://reactome.org/PathwayBrowser/#/R-RNO-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Rattus norvegicus 33019 R-RNO-5691001 https://reactome.org/PathwayBrowser/#/R-RNO-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Rattus norvegicus 33019 R-RNO-5693593 https://reactome.org/PathwayBrowser/#/R-RNO-5693593 D-loop extension by DNA polymerases IEA Rattus norvegicus 33019 R-RNO-5694494 https://reactome.org/PathwayBrowser/#/R-RNO-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Rattus norvegicus 33019 R-RNO-5695957 https://reactome.org/PathwayBrowser/#/R-RNO-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Rattus norvegicus 33019 R-RNO-5696004 https://reactome.org/PathwayBrowser/#/R-RNO-5696004 ACSF2 ligates CoA-SH to MCFA IEA Rattus norvegicus 33019 R-RNO-5696007 https://reactome.org/PathwayBrowser/#/R-RNO-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Rattus norvegicus 33019 R-RNO-6781824 https://reactome.org/PathwayBrowser/#/R-RNO-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Rattus norvegicus 33019 R-RNO-6782208 https://reactome.org/PathwayBrowser/#/R-RNO-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Rattus norvegicus 33019 R-RNO-6786166 https://reactome.org/PathwayBrowser/#/R-RNO-6786166 Translesion synthesis across unhooked ICL by POLN IEA Rattus norvegicus 33019 R-RNO-6787533 https://reactome.org/PathwayBrowser/#/R-RNO-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Rattus norvegicus 33019 R-RNO-6788912 https://reactome.org/PathwayBrowser/#/R-RNO-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Rattus norvegicus 33019 R-RNO-6806674 https://reactome.org/PathwayBrowser/#/R-RNO-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 33019 R-RNO-70286 https://reactome.org/PathwayBrowser/#/R-RNO-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Rattus norvegicus 33019 R-RNO-70599 https://reactome.org/PathwayBrowser/#/R-RNO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Rattus norvegicus 33019 R-RNO-71732 https://reactome.org/PathwayBrowser/#/R-RNO-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Rattus norvegicus 33019 R-RNO-71735 https://reactome.org/PathwayBrowser/#/R-RNO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Rattus norvegicus 33019 R-RNO-73567 https://reactome.org/PathwayBrowser/#/R-RNO-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Rattus norvegicus 33019 R-RNO-73666 https://reactome.org/PathwayBrowser/#/R-RNO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Rattus norvegicus 33019 R-RNO-73792 https://reactome.org/PathwayBrowser/#/R-RNO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Rattus norvegicus 33019 R-RNO-73815 https://reactome.org/PathwayBrowser/#/R-RNO-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Rattus norvegicus 33019 R-RNO-73932 https://reactome.org/PathwayBrowser/#/R-RNO-73932 Resynthesis of excised residue by POLB IEA Rattus norvegicus 33019 R-RNO-74213 https://reactome.org/PathwayBrowser/#/R-RNO-74213 APRT catalyzes the conversion of adenine to AMP IEA Rattus norvegicus 33019 R-RNO-74215 https://reactome.org/PathwayBrowser/#/R-RNO-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Rattus norvegicus 33019 R-RNO-74885 https://reactome.org/PathwayBrowser/#/R-RNO-74885 GUCYs converts GTP to cGMP IEA Rattus norvegicus 33019 R-RNO-749516 https://reactome.org/PathwayBrowser/#/R-RNO-749516 Mannose-1-phosphate converted to GDP-Mannose TAS Rattus norvegicus 33019 R-RNO-75850 https://reactome.org/PathwayBrowser/#/R-RNO-75850 Addition of the third nucleotide on the nascent transcript IEA Rattus norvegicus 33019 R-RNO-75864 https://reactome.org/PathwayBrowser/#/R-RNO-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Rattus norvegicus 33019 R-RNO-75869 https://reactome.org/PathwayBrowser/#/R-RNO-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Rattus norvegicus 33019 R-RNO-75873 https://reactome.org/PathwayBrowser/#/R-RNO-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Rattus norvegicus 33019 R-RNO-76576 https://reactome.org/PathwayBrowser/#/R-RNO-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Rattus norvegicus 33019 R-RNO-8852128 https://reactome.org/PathwayBrowser/#/R-RNO-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Rattus norvegicus 33019 R-RNO-8852131 https://reactome.org/PathwayBrowser/#/R-RNO-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Rattus norvegicus 33019 R-RNO-8852132 https://reactome.org/PathwayBrowser/#/R-RNO-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Rattus norvegicus 33019 R-RNO-8852134 https://reactome.org/PathwayBrowser/#/R-RNO-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Rattus norvegicus 33019 R-RNO-8870469 https://reactome.org/PathwayBrowser/#/R-RNO-8870469 RGGT geranylgeranylates RAB proteins IEA Rattus norvegicus 33019 R-RNO-8875071 https://reactome.org/PathwayBrowser/#/R-RNO-8875071 ACSS3 ligates CoA to CH3COO- IEA Rattus norvegicus 33019 R-RNO-8939959 https://reactome.org/PathwayBrowser/#/R-RNO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Rattus norvegicus 33019 R-RNO-8951648 https://reactome.org/PathwayBrowser/#/R-RNO-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Rattus norvegicus 33019 R-RNO-8951656 https://reactome.org/PathwayBrowser/#/R-RNO-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Rattus norvegicus 33019 R-RNO-947531 https://reactome.org/PathwayBrowser/#/R-RNO-947531 Molybdenum ion transfer onto molybdopterin IEA Rattus norvegicus 33019 R-RNO-947535 https://reactome.org/PathwayBrowser/#/R-RNO-947535 Cyclisation of GTP to precursor Z IEA Rattus norvegicus 33019 R-RNO-9613494 https://reactome.org/PathwayBrowser/#/R-RNO-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Rattus norvegicus 33019 R-RNO-9613497 https://reactome.org/PathwayBrowser/#/R-RNO-9613497 Unwinding DNA for the nascent transcript IEA Rattus norvegicus 33019 R-RNO-9617504 https://reactome.org/PathwayBrowser/#/R-RNO-9617504 Calmodulin-activated adenylate cyclases Adcy1 and Adcy8 generate cAMP TAS Rattus norvegicus 33019 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 33019 R-RNO-9713735 https://reactome.org/PathwayBrowser/#/R-RNO-9713735 Adcy3:Gnal:GTP converts ATP to cAMP TAS Rattus norvegicus 33019 R-RNO-9717830 https://reactome.org/PathwayBrowser/#/R-RNO-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Rattus norvegicus 33019 R-RNO-9717834 https://reactome.org/PathwayBrowser/#/R-RNO-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Rattus norvegicus 33019 R-RNO-9731228 https://reactome.org/PathwayBrowser/#/R-RNO-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Rattus norvegicus 33019 R-RNO-9731590 https://reactome.org/PathwayBrowser/#/R-RNO-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Rattus norvegicus 33019 R-RNO-9731613 https://reactome.org/PathwayBrowser/#/R-RNO-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Rattus norvegicus 33019 R-RNO-9731632 https://reactome.org/PathwayBrowser/#/R-RNO-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Rattus norvegicus 33019 R-RNO-9734535 https://reactome.org/PathwayBrowser/#/R-RNO-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Rattus norvegicus 33019 R-RNO-9748951 https://reactome.org/PathwayBrowser/#/R-RNO-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Rattus norvegicus 33019 R-RNO-9748957 https://reactome.org/PathwayBrowser/#/R-RNO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Rattus norvegicus 33019 R-RNO-9749971 https://reactome.org/PathwayBrowser/#/R-RNO-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Rattus norvegicus 33019 R-RNO-9750555 https://reactome.org/PathwayBrowser/#/R-RNO-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Rattus norvegicus 33019 R-RNO-9755030 https://reactome.org/PathwayBrowser/#/R-RNO-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Rattus norvegicus 33019 R-RNO-9760094 https://reactome.org/PathwayBrowser/#/R-RNO-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Rattus norvegicus 33019 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus 33019 R-RNO-983153 https://reactome.org/PathwayBrowser/#/R-RNO-983153 E1 mediated ubiquitin activation IEA Rattus norvegicus 33019 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus 33019 R-RNO-9833973 https://reactome.org/PathwayBrowser/#/R-RNO-9833973 ISGylation of PKR IEA Rattus norvegicus 33019 R-SCE-110311 https://reactome.org/PathwayBrowser/#/R-SCE-110311 POLZ extends translesion synthesis IEA Saccharomyces cerevisiae 33019 R-SCE-110317 https://reactome.org/PathwayBrowser/#/R-SCE-110317 Insertion of correct bases opposite the lesion by POLH IEA Saccharomyces cerevisiae 33019 R-SCE-110319 https://reactome.org/PathwayBrowser/#/R-SCE-110319 Elongation by POLH IEA Saccharomyces cerevisiae 33019 R-SCE-111264 https://reactome.org/PathwayBrowser/#/R-SCE-111264 Addition of nucleotides between position +11 and +30 IEA Saccharomyces cerevisiae 33019 R-SCE-1483081 https://reactome.org/PathwayBrowser/#/R-SCE-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Saccharomyces cerevisiae 33019 R-SCE-1483121 https://reactome.org/PathwayBrowser/#/R-SCE-1483121 PA is converted to CDP-DAG by CDS1 IEA Saccharomyces cerevisiae 33019 R-SCE-1483165 https://reactome.org/PathwayBrowser/#/R-SCE-1483165 PA is converted to CDP-DAG by CDS2 IEA Saccharomyces cerevisiae 33019 R-SCE-1483190 https://reactome.org/PathwayBrowser/#/R-SCE-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Saccharomyces cerevisiae 33019 R-SCE-159425 https://reactome.org/PathwayBrowser/#/R-SCE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 33019 R-SCE-174124 https://reactome.org/PathwayBrowser/#/R-SCE-174124 Dephosphorylation of phospho-Cdh1 IEA Saccharomyces cerevisiae 33019 R-SCE-174391 https://reactome.org/PathwayBrowser/#/R-SCE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Saccharomyces cerevisiae 33019 R-SCE-174392 https://reactome.org/PathwayBrowser/#/R-SCE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Saccharomyces cerevisiae 33019 R-SCE-191303 https://reactome.org/PathwayBrowser/#/R-SCE-191303 FDPS dimer transfers IPPP to GPP IEA Saccharomyces cerevisiae 33019 R-SCE-191322 https://reactome.org/PathwayBrowser/#/R-SCE-191322 FDPS dimer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 33019 R-SCE-191402 https://reactome.org/PathwayBrowser/#/R-SCE-191402 Reduction of presqualene diphosphate to form squalene IEA Saccharomyces cerevisiae 33019 R-SCE-191405 https://reactome.org/PathwayBrowser/#/R-SCE-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Saccharomyces cerevisiae 33019 R-SCE-192137 https://reactome.org/PathwayBrowser/#/R-SCE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 33019 R-SCE-193401 https://reactome.org/PathwayBrowser/#/R-SCE-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 33019 R-SCE-193407 https://reactome.org/PathwayBrowser/#/R-SCE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 33019 R-SCE-193424 https://reactome.org/PathwayBrowser/#/R-SCE-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 33019 R-SCE-193711 https://reactome.org/PathwayBrowser/#/R-SCE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 33019 R-SCE-193727 https://reactome.org/PathwayBrowser/#/R-SCE-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 33019 R-SCE-193743 https://reactome.org/PathwayBrowser/#/R-SCE-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 33019 R-SCE-193766 https://reactome.org/PathwayBrowser/#/R-SCE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 33019 R-SCE-196753 https://reactome.org/PathwayBrowser/#/R-SCE-196753 2xPPCS ligates PPanK with Cys IEA Saccharomyces cerevisiae 33019 R-SCE-196754 https://reactome.org/PathwayBrowser/#/R-SCE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Saccharomyces cerevisiae 33019 R-SCE-196929 https://reactome.org/PathwayBrowser/#/R-SCE-196929 FLAD1 phosphorylates FMN IEA Saccharomyces cerevisiae 33019 R-SCE-197186 https://reactome.org/PathwayBrowser/#/R-SCE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Saccharomyces cerevisiae 33019 R-SCE-197235 https://reactome.org/PathwayBrowser/#/R-SCE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 33019 R-SCE-197268 https://reactome.org/PathwayBrowser/#/R-SCE-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Saccharomyces cerevisiae 33019 R-SCE-197271 https://reactome.org/PathwayBrowser/#/R-SCE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Saccharomyces cerevisiae 33019 R-SCE-200474 https://reactome.org/PathwayBrowser/#/R-SCE-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 33019 R-SCE-200512 https://reactome.org/PathwayBrowser/#/R-SCE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 33019 R-SCE-201035 https://reactome.org/PathwayBrowser/#/R-SCE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Saccharomyces cerevisiae 33019 R-SCE-2162192 https://reactome.org/PathwayBrowser/#/R-SCE-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Saccharomyces cerevisiae 33019 R-SCE-2162253 https://reactome.org/PathwayBrowser/#/R-SCE-2162253 PDSS1,2 ligates FPP to IPPP IEA Saccharomyces cerevisiae 33019 R-SCE-2408551 https://reactome.org/PathwayBrowser/#/R-SCE-2408551 SeMet is converted to AdoSeMet by MAT IEA Saccharomyces cerevisiae 33019 R-SCE-2509827 https://reactome.org/PathwayBrowser/#/R-SCE-2509827 ITPA hydrolyses ITP to IMP IEA Saccharomyces cerevisiae 33019 R-SCE-2509831 https://reactome.org/PathwayBrowser/#/R-SCE-2509831 ITPA hydrolyses XTP to XMP IEA Saccharomyces cerevisiae 33019 R-SCE-2509838 https://reactome.org/PathwayBrowser/#/R-SCE-2509838 ITPA hydrolyses dITP to dIMP IEA Saccharomyces cerevisiae 33019 R-SCE-2990833 https://reactome.org/PathwayBrowser/#/R-SCE-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Saccharomyces cerevisiae 33019 R-SCE-2993802 https://reactome.org/PathwayBrowser/#/R-SCE-2993802 HLCS biotinylates PC:Mn2+ IEA Saccharomyces cerevisiae 33019 R-SCE-2993814 https://reactome.org/PathwayBrowser/#/R-SCE-2993814 HLCS biotinylates ACACA:Mn2+ IEA Saccharomyces cerevisiae 33019 R-SCE-2995330 https://reactome.org/PathwayBrowser/#/R-SCE-2995330 COX10 transforms heme to heme O IEA Saccharomyces cerevisiae 33019 R-SCE-389622 https://reactome.org/PathwayBrowser/#/R-SCE-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 33019 R-SCE-389632 https://reactome.org/PathwayBrowser/#/R-SCE-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 33019 R-SCE-4167511 https://reactome.org/PathwayBrowser/#/R-SCE-4167511 HLCS biotinylates ACACB IEA Saccharomyces cerevisiae 33019 R-SCE-434382 https://reactome.org/PathwayBrowser/#/R-SCE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Saccharomyces cerevisiae 33019 R-SCE-446204 https://reactome.org/PathwayBrowser/#/R-SCE-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Saccharomyces cerevisiae 33019 R-SCE-449911 https://reactome.org/PathwayBrowser/#/R-SCE-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Saccharomyces cerevisiae 33019 R-SCE-449937 https://reactome.org/PathwayBrowser/#/R-SCE-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Saccharomyces cerevisiae 33019 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 33019 R-SCE-5358475 https://reactome.org/PathwayBrowser/#/R-SCE-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Saccharomyces cerevisiae 33019 R-SCE-5358592 https://reactome.org/PathwayBrowser/#/R-SCE-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Saccharomyces cerevisiae 33019 R-SCE-548843 https://reactome.org/PathwayBrowser/#/R-SCE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Saccharomyces cerevisiae 33019 R-SCE-5655892 https://reactome.org/PathwayBrowser/#/R-SCE-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Saccharomyces cerevisiae 33019 R-SCE-5655965 https://reactome.org/PathwayBrowser/#/R-SCE-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Saccharomyces cerevisiae 33019 R-SCE-5656148 https://reactome.org/PathwayBrowser/#/R-SCE-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Saccharomyces cerevisiae 33019 R-SCE-5656158 https://reactome.org/PathwayBrowser/#/R-SCE-5656158 POLZ elongates POLI-incorporated dNMP IEA Saccharomyces cerevisiae 33019 R-SCE-5691001 https://reactome.org/PathwayBrowser/#/R-SCE-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Saccharomyces cerevisiae 33019 R-SCE-6781824 https://reactome.org/PathwayBrowser/#/R-SCE-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Saccharomyces cerevisiae 33019 R-SCE-6782208 https://reactome.org/PathwayBrowser/#/R-SCE-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Saccharomyces cerevisiae 33019 R-SCE-6790167 https://reactome.org/PathwayBrowser/#/R-SCE-6790167 MOD5 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) TAS Saccharomyces cerevisiae 33019 R-SCE-70286 https://reactome.org/PathwayBrowser/#/R-SCE-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Saccharomyces cerevisiae 33019 R-SCE-70599 https://reactome.org/PathwayBrowser/#/R-SCE-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Saccharomyces cerevisiae 33019 R-SCE-71732 https://reactome.org/PathwayBrowser/#/R-SCE-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Saccharomyces cerevisiae 33019 R-SCE-71735 https://reactome.org/PathwayBrowser/#/R-SCE-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Saccharomyces cerevisiae 33019 R-SCE-73666 https://reactome.org/PathwayBrowser/#/R-SCE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Saccharomyces cerevisiae 33019 R-SCE-73792 https://reactome.org/PathwayBrowser/#/R-SCE-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Saccharomyces cerevisiae 33019 R-SCE-74213 https://reactome.org/PathwayBrowser/#/R-SCE-74213 APRT catalyzes the conversion of adenine to AMP IEA Saccharomyces cerevisiae 33019 R-SCE-75850 https://reactome.org/PathwayBrowser/#/R-SCE-75850 Addition of the third nucleotide on the nascent transcript IEA Saccharomyces cerevisiae 33019 R-SCE-75864 https://reactome.org/PathwayBrowser/#/R-SCE-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Saccharomyces cerevisiae 33019 R-SCE-75869 https://reactome.org/PathwayBrowser/#/R-SCE-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Saccharomyces cerevisiae 33019 R-SCE-75873 https://reactome.org/PathwayBrowser/#/R-SCE-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Saccharomyces cerevisiae 33019 R-SCE-76576 https://reactome.org/PathwayBrowser/#/R-SCE-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Saccharomyces cerevisiae 33019 R-SCE-8852128 https://reactome.org/PathwayBrowser/#/R-SCE-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Saccharomyces cerevisiae 33019 R-SCE-8852131 https://reactome.org/PathwayBrowser/#/R-SCE-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Saccharomyces cerevisiae 33019 R-SCE-8852132 https://reactome.org/PathwayBrowser/#/R-SCE-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Saccharomyces cerevisiae 33019 R-SCE-8852134 https://reactome.org/PathwayBrowser/#/R-SCE-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Saccharomyces cerevisiae 33019 R-SCE-8870469 https://reactome.org/PathwayBrowser/#/R-SCE-8870469 RGGT geranylgeranylates RAB proteins IEA Saccharomyces cerevisiae 33019 R-SCE-8939959 https://reactome.org/PathwayBrowser/#/R-SCE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Saccharomyces cerevisiae 33019 R-SCE-8951648 https://reactome.org/PathwayBrowser/#/R-SCE-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Saccharomyces cerevisiae 33019 R-SCE-8951656 https://reactome.org/PathwayBrowser/#/R-SCE-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Saccharomyces cerevisiae 33019 R-SCE-9613494 https://reactome.org/PathwayBrowser/#/R-SCE-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Saccharomyces cerevisiae 33019 R-SCE-9613497 https://reactome.org/PathwayBrowser/#/R-SCE-9613497 Unwinding DNA for the nascent transcript IEA Saccharomyces cerevisiae 33019 R-SCE-9717830 https://reactome.org/PathwayBrowser/#/R-SCE-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Saccharomyces cerevisiae 33019 R-SCE-9717834 https://reactome.org/PathwayBrowser/#/R-SCE-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 33019 R-SCE-9734535 https://reactome.org/PathwayBrowser/#/R-SCE-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Saccharomyces cerevisiae 33019 R-SCE-9748957 https://reactome.org/PathwayBrowser/#/R-SCE-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Saccharomyces cerevisiae 33019 R-SCE-9755030 https://reactome.org/PathwayBrowser/#/R-SCE-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Saccharomyces cerevisiae 33019 R-SCE-9760094 https://reactome.org/PathwayBrowser/#/R-SCE-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Saccharomyces cerevisiae 33019 R-SCE-983140 https://reactome.org/PathwayBrowser/#/R-SCE-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Saccharomyces cerevisiae 33019 R-SCE-983153 https://reactome.org/PathwayBrowser/#/R-SCE-983153 E1 mediated ubiquitin activation IEA Saccharomyces cerevisiae 33019 R-SCE-983156 https://reactome.org/PathwayBrowser/#/R-SCE-983156 Polyubiquitination of substrate IEA Saccharomyces cerevisiae 33019 R-SPO-110311 https://reactome.org/PathwayBrowser/#/R-SPO-110311 POLZ extends translesion synthesis IEA Schizosaccharomyces pombe 33019 R-SPO-110317 https://reactome.org/PathwayBrowser/#/R-SPO-110317 Insertion of correct bases opposite the lesion by POLH IEA Schizosaccharomyces pombe 33019 R-SPO-110319 https://reactome.org/PathwayBrowser/#/R-SPO-110319 Elongation by POLH IEA Schizosaccharomyces pombe 33019 R-SPO-110368 https://reactome.org/PathwayBrowser/#/R-SPO-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Schizosaccharomyces pombe 33019 R-SPO-111264 https://reactome.org/PathwayBrowser/#/R-SPO-111264 Addition of nucleotides between position +11 and +30 IEA Schizosaccharomyces pombe 33019 R-SPO-1483081 https://reactome.org/PathwayBrowser/#/R-SPO-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Schizosaccharomyces pombe 33019 R-SPO-1483121 https://reactome.org/PathwayBrowser/#/R-SPO-1483121 PA is converted to CDP-DAG by CDS1 IEA Schizosaccharomyces pombe 33019 R-SPO-1483165 https://reactome.org/PathwayBrowser/#/R-SPO-1483165 PA is converted to CDP-DAG by CDS2 IEA Schizosaccharomyces pombe 33019 R-SPO-1483190 https://reactome.org/PathwayBrowser/#/R-SPO-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Schizosaccharomyces pombe 33019 R-SPO-174124 https://reactome.org/PathwayBrowser/#/R-SPO-174124 Dephosphorylation of phospho-Cdh1 IEA Schizosaccharomyces pombe 33019 R-SPO-174391 https://reactome.org/PathwayBrowser/#/R-SPO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Schizosaccharomyces pombe 33019 R-SPO-174392 https://reactome.org/PathwayBrowser/#/R-SPO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Schizosaccharomyces pombe 33019 R-SPO-191303 https://reactome.org/PathwayBrowser/#/R-SPO-191303 FDPS dimer transfers IPPP to GPP IEA Schizosaccharomyces pombe 33019 R-SPO-191322 https://reactome.org/PathwayBrowser/#/R-SPO-191322 FDPS dimer transfers IPPP to DMAPP IEA Schizosaccharomyces pombe 33019 R-SPO-191402 https://reactome.org/PathwayBrowser/#/R-SPO-191402 Reduction of presqualene diphosphate to form squalene IEA Schizosaccharomyces pombe 33019 R-SPO-191405 https://reactome.org/PathwayBrowser/#/R-SPO-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Schizosaccharomyces pombe 33019 R-SPO-196753 https://reactome.org/PathwayBrowser/#/R-SPO-196753 2xPPCS ligates PPanK with Cys IEA Schizosaccharomyces pombe 33019 R-SPO-196754 https://reactome.org/PathwayBrowser/#/R-SPO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Schizosaccharomyces pombe 33019 R-SPO-196929 https://reactome.org/PathwayBrowser/#/R-SPO-196929 FLAD1 phosphorylates FMN IEA Schizosaccharomyces pombe 33019 R-SPO-197186 https://reactome.org/PathwayBrowser/#/R-SPO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Schizosaccharomyces pombe 33019 R-SPO-197235 https://reactome.org/PathwayBrowser/#/R-SPO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 33019 R-SPO-197271 https://reactome.org/PathwayBrowser/#/R-SPO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Schizosaccharomyces pombe 33019 R-SPO-200474 https://reactome.org/PathwayBrowser/#/R-SPO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 33019 R-SPO-200512 https://reactome.org/PathwayBrowser/#/R-SPO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 33019 R-SPO-201035 https://reactome.org/PathwayBrowser/#/R-SPO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Schizosaccharomyces pombe 33019 R-SPO-2162192 https://reactome.org/PathwayBrowser/#/R-SPO-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Schizosaccharomyces pombe 33019 R-SPO-2162253 https://reactome.org/PathwayBrowser/#/R-SPO-2162253 PDSS1,2 ligates FPP to IPPP IEA Schizosaccharomyces pombe 33019 R-SPO-2408551 https://reactome.org/PathwayBrowser/#/R-SPO-2408551 SeMet is converted to AdoSeMet by MAT IEA Schizosaccharomyces pombe 33019 R-SPO-2509827 https://reactome.org/PathwayBrowser/#/R-SPO-2509827 ITPA hydrolyses ITP to IMP IEA Schizosaccharomyces pombe 33019 R-SPO-2509831 https://reactome.org/PathwayBrowser/#/R-SPO-2509831 ITPA hydrolyses XTP to XMP IEA Schizosaccharomyces pombe 33019 R-SPO-2509838 https://reactome.org/PathwayBrowser/#/R-SPO-2509838 ITPA hydrolyses dITP to dIMP IEA Schizosaccharomyces pombe 33019 R-SPO-2990833 https://reactome.org/PathwayBrowser/#/R-SPO-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Schizosaccharomyces pombe 33019 R-SPO-2993802 https://reactome.org/PathwayBrowser/#/R-SPO-2993802 HLCS biotinylates PC:Mn2+ IEA Schizosaccharomyces pombe 33019 R-SPO-2993814 https://reactome.org/PathwayBrowser/#/R-SPO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Schizosaccharomyces pombe 33019 R-SPO-2995330 https://reactome.org/PathwayBrowser/#/R-SPO-2995330 COX10 transforms heme to heme O IEA Schizosaccharomyces pombe 33019 R-SPO-4167511 https://reactome.org/PathwayBrowser/#/R-SPO-4167511 HLCS biotinylates ACACB IEA Schizosaccharomyces pombe 33019 R-SPO-434382 https://reactome.org/PathwayBrowser/#/R-SPO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Schizosaccharomyces pombe 33019 R-SPO-446204 https://reactome.org/PathwayBrowser/#/R-SPO-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Schizosaccharomyces pombe 33019 R-SPO-449911 https://reactome.org/PathwayBrowser/#/R-SPO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Schizosaccharomyces pombe 33019 R-SPO-449937 https://reactome.org/PathwayBrowser/#/R-SPO-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Schizosaccharomyces pombe 33019 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 33019 R-SPO-5358475 https://reactome.org/PathwayBrowser/#/R-SPO-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Schizosaccharomyces pombe 33019 R-SPO-5358592 https://reactome.org/PathwayBrowser/#/R-SPO-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Schizosaccharomyces pombe 33019 R-SPO-548843 https://reactome.org/PathwayBrowser/#/R-SPO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Schizosaccharomyces pombe 33019 R-SPO-5655892 https://reactome.org/PathwayBrowser/#/R-SPO-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Schizosaccharomyces pombe 33019 R-SPO-5655965 https://reactome.org/PathwayBrowser/#/R-SPO-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Schizosaccharomyces pombe 33019 R-SPO-5656148 https://reactome.org/PathwayBrowser/#/R-SPO-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Schizosaccharomyces pombe 33019 R-SPO-5656158 https://reactome.org/PathwayBrowser/#/R-SPO-5656158 POLZ elongates POLI-incorporated dNMP IEA Schizosaccharomyces pombe 33019 R-SPO-5691001 https://reactome.org/PathwayBrowser/#/R-SPO-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Schizosaccharomyces pombe 33019 R-SPO-6781824 https://reactome.org/PathwayBrowser/#/R-SPO-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Schizosaccharomyces pombe 33019 R-SPO-6782208 https://reactome.org/PathwayBrowser/#/R-SPO-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Schizosaccharomyces pombe 33019 R-SPO-70286 https://reactome.org/PathwayBrowser/#/R-SPO-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Schizosaccharomyces pombe 33019 R-SPO-70599 https://reactome.org/PathwayBrowser/#/R-SPO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Schizosaccharomyces pombe 33019 R-SPO-71732 https://reactome.org/PathwayBrowser/#/R-SPO-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Schizosaccharomyces pombe 33019 R-SPO-71735 https://reactome.org/PathwayBrowser/#/R-SPO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Schizosaccharomyces pombe 33019 R-SPO-73666 https://reactome.org/PathwayBrowser/#/R-SPO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Schizosaccharomyces pombe 33019 R-SPO-73792 https://reactome.org/PathwayBrowser/#/R-SPO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Schizosaccharomyces pombe 33019 R-SPO-74213 https://reactome.org/PathwayBrowser/#/R-SPO-74213 APRT catalyzes the conversion of adenine to AMP IEA Schizosaccharomyces pombe 33019 R-SPO-75850 https://reactome.org/PathwayBrowser/#/R-SPO-75850 Addition of the third nucleotide on the nascent transcript IEA Schizosaccharomyces pombe 33019 R-SPO-75864 https://reactome.org/PathwayBrowser/#/R-SPO-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Schizosaccharomyces pombe 33019 R-SPO-75869 https://reactome.org/PathwayBrowser/#/R-SPO-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Schizosaccharomyces pombe 33019 R-SPO-75873 https://reactome.org/PathwayBrowser/#/R-SPO-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Schizosaccharomyces pombe 33019 R-SPO-76576 https://reactome.org/PathwayBrowser/#/R-SPO-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Schizosaccharomyces pombe 33019 R-SPO-8852128 https://reactome.org/PathwayBrowser/#/R-SPO-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Schizosaccharomyces pombe 33019 R-SPO-8852131 https://reactome.org/PathwayBrowser/#/R-SPO-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Schizosaccharomyces pombe 33019 R-SPO-8852132 https://reactome.org/PathwayBrowser/#/R-SPO-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Schizosaccharomyces pombe 33019 R-SPO-8852134 https://reactome.org/PathwayBrowser/#/R-SPO-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Schizosaccharomyces pombe 33019 R-SPO-8870469 https://reactome.org/PathwayBrowser/#/R-SPO-8870469 RGGT geranylgeranylates RAB proteins IEA Schizosaccharomyces pombe 33019 R-SPO-8939959 https://reactome.org/PathwayBrowser/#/R-SPO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Schizosaccharomyces pombe 33019 R-SPO-8951648 https://reactome.org/PathwayBrowser/#/R-SPO-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Schizosaccharomyces pombe 33019 R-SPO-8951656 https://reactome.org/PathwayBrowser/#/R-SPO-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Schizosaccharomyces pombe 33019 R-SPO-9613494 https://reactome.org/PathwayBrowser/#/R-SPO-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Schizosaccharomyces pombe 33019 R-SPO-9613497 https://reactome.org/PathwayBrowser/#/R-SPO-9613497 Unwinding DNA for the nascent transcript IEA Schizosaccharomyces pombe 33019 R-SPO-9748957 https://reactome.org/PathwayBrowser/#/R-SPO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Schizosaccharomyces pombe 33019 R-SPO-9755030 https://reactome.org/PathwayBrowser/#/R-SPO-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Schizosaccharomyces pombe 33019 R-SPO-9760094 https://reactome.org/PathwayBrowser/#/R-SPO-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Schizosaccharomyces pombe 33019 R-SPO-983140 https://reactome.org/PathwayBrowser/#/R-SPO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Schizosaccharomyces pombe 33019 R-SPO-983153 https://reactome.org/PathwayBrowser/#/R-SPO-983153 E1 mediated ubiquitin activation IEA Schizosaccharomyces pombe 33019 R-SPO-983156 https://reactome.org/PathwayBrowser/#/R-SPO-983156 Polyubiquitination of substrate IEA Schizosaccharomyces pombe 33019 R-SSC-110311 https://reactome.org/PathwayBrowser/#/R-SSC-110311 POLZ extends translesion synthesis IEA Sus scrofa 33019 R-SSC-110317 https://reactome.org/PathwayBrowser/#/R-SSC-110317 Insertion of correct bases opposite the lesion by POLH IEA Sus scrofa 33019 R-SSC-110319 https://reactome.org/PathwayBrowser/#/R-SSC-110319 Elongation by POLH IEA Sus scrofa 33019 R-SSC-110368 https://reactome.org/PathwayBrowser/#/R-SSC-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Sus scrofa 33019 R-SSC-111253 https://reactome.org/PathwayBrowser/#/R-SSC-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Sus scrofa 33019 R-SSC-111264 https://reactome.org/PathwayBrowser/#/R-SSC-111264 Addition of nucleotides between position +11 and +30 IEA Sus scrofa 33019 R-SSC-111930 https://reactome.org/PathwayBrowser/#/R-SSC-111930 Adenylate cyclase produces cAMP IEA Sus scrofa 33019 R-SSC-1169394 https://reactome.org/PathwayBrowser/#/R-SSC-1169394 ISGylation of IRF3 IEA Sus scrofa 33019 R-SSC-1169397 https://reactome.org/PathwayBrowser/#/R-SSC-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Sus scrofa 33019 R-SSC-1169398 https://reactome.org/PathwayBrowser/#/R-SSC-1169398 ISGylation of host protein filamin B IEA Sus scrofa 33019 R-SSC-1169402 https://reactome.org/PathwayBrowser/#/R-SSC-1169402 ISGylation of E2 conjugating enzymes IEA Sus scrofa 33019 R-SSC-1169405 https://reactome.org/PathwayBrowser/#/R-SSC-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Sus scrofa 33019 R-SSC-1169406 https://reactome.org/PathwayBrowser/#/R-SSC-1169406 ISGylation of host proteins IEA Sus scrofa 33019 R-SSC-1483081 https://reactome.org/PathwayBrowser/#/R-SSC-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Sus scrofa 33019 R-SSC-1483121 https://reactome.org/PathwayBrowser/#/R-SSC-1483121 PA is converted to CDP-DAG by CDS1 IEA Sus scrofa 33019 R-SSC-1483165 https://reactome.org/PathwayBrowser/#/R-SSC-1483165 PA is converted to CDP-DAG by CDS2 IEA Sus scrofa 33019 R-SSC-1483190 https://reactome.org/PathwayBrowser/#/R-SSC-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Sus scrofa 33019 R-SSC-159425 https://reactome.org/PathwayBrowser/#/R-SSC-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 33019 R-SSC-159443 https://reactome.org/PathwayBrowser/#/R-SSC-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 33019 R-SSC-159567 https://reactome.org/PathwayBrowser/#/R-SSC-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Sus scrofa 33019 R-SSC-170676 https://reactome.org/PathwayBrowser/#/R-SSC-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Sus scrofa 33019 R-SSC-174124 https://reactome.org/PathwayBrowser/#/R-SSC-174124 Dephosphorylation of phospho-Cdh1 IEA Sus scrofa 33019 R-SSC-174391 https://reactome.org/PathwayBrowser/#/R-SSC-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Sus scrofa 33019 R-SSC-174392 https://reactome.org/PathwayBrowser/#/R-SSC-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Sus scrofa 33019 R-SSC-177157 https://reactome.org/PathwayBrowser/#/R-SSC-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Sus scrofa 33019 R-SSC-191303 https://reactome.org/PathwayBrowser/#/R-SSC-191303 FDPS dimer transfers IPPP to GPP IEA Sus scrofa 33019 R-SSC-191322 https://reactome.org/PathwayBrowser/#/R-SSC-191322 FDPS dimer transfers IPPP to DMAPP IEA Sus scrofa 33019 R-SSC-191402 https://reactome.org/PathwayBrowser/#/R-SSC-191402 Reduction of presqualene diphosphate to form squalene IEA Sus scrofa 33019 R-SSC-191405 https://reactome.org/PathwayBrowser/#/R-SSC-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Sus scrofa 33019 R-SSC-192137 https://reactome.org/PathwayBrowser/#/R-SSC-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 33019 R-SSC-193401 https://reactome.org/PathwayBrowser/#/R-SSC-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 33019 R-SSC-193407 https://reactome.org/PathwayBrowser/#/R-SSC-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 33019 R-SSC-193424 https://reactome.org/PathwayBrowser/#/R-SSC-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 33019 R-SSC-193711 https://reactome.org/PathwayBrowser/#/R-SSC-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 33019 R-SSC-193727 https://reactome.org/PathwayBrowser/#/R-SSC-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 33019 R-SSC-193743 https://reactome.org/PathwayBrowser/#/R-SSC-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 33019 R-SSC-193766 https://reactome.org/PathwayBrowser/#/R-SSC-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 33019 R-SSC-196753 https://reactome.org/PathwayBrowser/#/R-SSC-196753 2xPPCS ligates PPanK with Cys IEA Sus scrofa 33019 R-SSC-196754 https://reactome.org/PathwayBrowser/#/R-SSC-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Sus scrofa 33019 R-SSC-196929 https://reactome.org/PathwayBrowser/#/R-SSC-196929 FLAD1 phosphorylates FMN IEA Sus scrofa 33019 R-SSC-197186 https://reactome.org/PathwayBrowser/#/R-SSC-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Sus scrofa 33019 R-SSC-197235 https://reactome.org/PathwayBrowser/#/R-SSC-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 33019 R-SSC-197250 https://reactome.org/PathwayBrowser/#/R-SSC-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Sus scrofa 33019 R-SSC-197268 https://reactome.org/PathwayBrowser/#/R-SSC-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Sus scrofa 33019 R-SSC-197271 https://reactome.org/PathwayBrowser/#/R-SSC-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Sus scrofa 33019 R-SSC-200474 https://reactome.org/PathwayBrowser/#/R-SSC-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 33019 R-SSC-200512 https://reactome.org/PathwayBrowser/#/R-SSC-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 33019 R-SSC-201035 https://reactome.org/PathwayBrowser/#/R-SSC-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Sus scrofa 33019 R-SSC-2046085 https://reactome.org/PathwayBrowser/#/R-SSC-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Sus scrofa 33019 R-SSC-2046098 https://reactome.org/PathwayBrowser/#/R-SSC-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Sus scrofa 33019 R-SSC-2162192 https://reactome.org/PathwayBrowser/#/R-SSC-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Sus scrofa 33019 R-SSC-2162253 https://reactome.org/PathwayBrowser/#/R-SSC-2162253 PDSS1,2 ligates FPP to IPPP IEA Sus scrofa 33019 R-SSC-2395818 https://reactome.org/PathwayBrowser/#/R-SSC-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Sus scrofa 33019 R-SSC-2395849 https://reactome.org/PathwayBrowser/#/R-SSC-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 33019 R-SSC-2395869 https://reactome.org/PathwayBrowser/#/R-SSC-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 33019 R-SSC-2395872 https://reactome.org/PathwayBrowser/#/R-SSC-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Sus scrofa 33019 R-SSC-2408551 https://reactome.org/PathwayBrowser/#/R-SSC-2408551 SeMet is converted to AdoSeMet by MAT IEA Sus scrofa 33019 R-SSC-2509827 https://reactome.org/PathwayBrowser/#/R-SSC-2509827 ITPA hydrolyses ITP to IMP IEA Sus scrofa 33019 R-SSC-2509831 https://reactome.org/PathwayBrowser/#/R-SSC-2509831 ITPA hydrolyses XTP to XMP IEA Sus scrofa 33019 R-SSC-2509838 https://reactome.org/PathwayBrowser/#/R-SSC-2509838 ITPA hydrolyses dITP to dIMP IEA Sus scrofa 33019 R-SSC-2730904 https://reactome.org/PathwayBrowser/#/R-SSC-2730904 Auto-ubiquitination of TRAF6 IEA Sus scrofa 33019 R-SSC-2990833 https://reactome.org/PathwayBrowser/#/R-SSC-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Sus scrofa 33019 R-SSC-2993447 https://reactome.org/PathwayBrowser/#/R-SSC-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Sus scrofa 33019 R-SSC-2993799 https://reactome.org/PathwayBrowser/#/R-SSC-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Sus scrofa 33019 R-SSC-2993802 https://reactome.org/PathwayBrowser/#/R-SSC-2993802 HLCS biotinylates PC:Mn2+ IEA Sus scrofa 33019 R-SSC-2993814 https://reactome.org/PathwayBrowser/#/R-SSC-2993814 HLCS biotinylates ACACA:Mn2+ IEA Sus scrofa 33019 R-SSC-2995330 https://reactome.org/PathwayBrowser/#/R-SSC-2995330 COX10 transforms heme to heme O IEA Sus scrofa 33019 R-SSC-389622 https://reactome.org/PathwayBrowser/#/R-SSC-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 33019 R-SSC-389632 https://reactome.org/PathwayBrowser/#/R-SSC-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 33019 R-SSC-389758 https://reactome.org/PathwayBrowser/#/R-SSC-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Sus scrofa 33019 R-SSC-392513 https://reactome.org/PathwayBrowser/#/R-SSC-392513 Rap1 signal termination by Rap1GAPs IEA Sus scrofa 33019 R-SSC-4084982 https://reactome.org/PathwayBrowser/#/R-SSC-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Sus scrofa 33019 R-SSC-4167511 https://reactome.org/PathwayBrowser/#/R-SSC-4167511 HLCS biotinylates ACACB IEA Sus scrofa 33019 R-SSC-434382 https://reactome.org/PathwayBrowser/#/R-SSC-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Sus scrofa 33019 R-SSC-446204 https://reactome.org/PathwayBrowser/#/R-SSC-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Sus scrofa 33019 R-SSC-449911 https://reactome.org/PathwayBrowser/#/R-SSC-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Sus scrofa 33019 R-SSC-449937 https://reactome.org/PathwayBrowser/#/R-SSC-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Sus scrofa 33019 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 33019 R-SSC-5226964 https://reactome.org/PathwayBrowser/#/R-SSC-5226964 ANKH transports PPi from cytosol to extracellular region IEA Sus scrofa 33019 R-SSC-5358475 https://reactome.org/PathwayBrowser/#/R-SSC-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Sus scrofa 33019 R-SSC-5358592 https://reactome.org/PathwayBrowser/#/R-SSC-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Sus scrofa 33019 R-SSC-548843 https://reactome.org/PathwayBrowser/#/R-SSC-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Sus scrofa 33019 R-SSC-5603114 https://reactome.org/PathwayBrowser/#/R-SSC-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Sus scrofa 33019 R-SSC-5607756 https://reactome.org/PathwayBrowser/#/R-SSC-5607756 TRAF6 oligomer autoubiquitinates IEA Sus scrofa 33019 R-SSC-5607757 https://reactome.org/PathwayBrowser/#/R-SSC-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 IEA Sus scrofa 33019 R-SSC-5610727 https://reactome.org/PathwayBrowser/#/R-SSC-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Sus scrofa 33019 R-SSC-5649723 https://reactome.org/PathwayBrowser/#/R-SSC-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Sus scrofa 33019 R-SSC-5649883 https://reactome.org/PathwayBrowser/#/R-SSC-5649883 POLB-mediated DNA strand displacement synthesis IEA Sus scrofa 33019 R-SSC-5655892 https://reactome.org/PathwayBrowser/#/R-SSC-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Sus scrofa 33019 R-SSC-5655965 https://reactome.org/PathwayBrowser/#/R-SSC-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Sus scrofa 33019 R-SSC-5656148 https://reactome.org/PathwayBrowser/#/R-SSC-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Sus scrofa 33019 R-SSC-5656158 https://reactome.org/PathwayBrowser/#/R-SSC-5656158 POLZ elongates POLI-incorporated dNMP IEA Sus scrofa 33019 R-SSC-5687360 https://reactome.org/PathwayBrowser/#/R-SSC-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Sus scrofa 33019 R-SSC-5687640 https://reactome.org/PathwayBrowser/#/R-SSC-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Sus scrofa 33019 R-SSC-5691001 https://reactome.org/PathwayBrowser/#/R-SSC-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Sus scrofa 33019 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa 33019 R-SSC-5694494 https://reactome.org/PathwayBrowser/#/R-SSC-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Sus scrofa 33019 R-SSC-5695957 https://reactome.org/PathwayBrowser/#/R-SSC-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Sus scrofa 33019 R-SSC-5696004 https://reactome.org/PathwayBrowser/#/R-SSC-5696004 ACSF2 ligates CoA-SH to MCFA IEA Sus scrofa 33019 R-SSC-5696007 https://reactome.org/PathwayBrowser/#/R-SSC-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Sus scrofa 33019 R-SSC-6781824 https://reactome.org/PathwayBrowser/#/R-SSC-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Sus scrofa 33019 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa 33019 R-SSC-6786166 https://reactome.org/PathwayBrowser/#/R-SSC-6786166 Translesion synthesis across unhooked ICL by POLN IEA Sus scrofa 33019 R-SSC-6787533 https://reactome.org/PathwayBrowser/#/R-SSC-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Sus scrofa 33019 R-SSC-6788912 https://reactome.org/PathwayBrowser/#/R-SSC-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Sus scrofa 33019 R-SSC-6806674 https://reactome.org/PathwayBrowser/#/R-SSC-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Sus scrofa 33019 R-SSC-70286 https://reactome.org/PathwayBrowser/#/R-SSC-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Sus scrofa 33019 R-SSC-70577 https://reactome.org/PathwayBrowser/#/R-SSC-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Sus scrofa 33019 R-SSC-70599 https://reactome.org/PathwayBrowser/#/R-SSC-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Sus scrofa 33019 R-SSC-71732 https://reactome.org/PathwayBrowser/#/R-SSC-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Sus scrofa 33019 R-SSC-71735 https://reactome.org/PathwayBrowser/#/R-SSC-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Sus scrofa 33019 R-SSC-73567 https://reactome.org/PathwayBrowser/#/R-SSC-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Sus scrofa 33019 R-SSC-73666 https://reactome.org/PathwayBrowser/#/R-SSC-73666 dUTP + H2O => dUMP + pyrophosphate IEA Sus scrofa 33019 R-SSC-73792 https://reactome.org/PathwayBrowser/#/R-SSC-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Sus scrofa 33019 R-SSC-73815 https://reactome.org/PathwayBrowser/#/R-SSC-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Sus scrofa 33019 R-SSC-73932 https://reactome.org/PathwayBrowser/#/R-SSC-73932 Resynthesis of excised residue by POLB IEA Sus scrofa 33019 R-SSC-74213 https://reactome.org/PathwayBrowser/#/R-SSC-74213 APRT catalyzes the conversion of adenine to AMP IEA Sus scrofa 33019 R-SSC-74215 https://reactome.org/PathwayBrowser/#/R-SSC-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Sus scrofa 33019 R-SSC-74885 https://reactome.org/PathwayBrowser/#/R-SSC-74885 GUCYs converts GTP to cGMP IEA Sus scrofa 33019 R-SSC-75850 https://reactome.org/PathwayBrowser/#/R-SSC-75850 Addition of the third nucleotide on the nascent transcript IEA Sus scrofa 33019 R-SSC-75864 https://reactome.org/PathwayBrowser/#/R-SSC-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Sus scrofa 33019 R-SSC-75869 https://reactome.org/PathwayBrowser/#/R-SSC-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Sus scrofa 33019 R-SSC-75873 https://reactome.org/PathwayBrowser/#/R-SSC-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Sus scrofa 33019 R-SSC-76576 https://reactome.org/PathwayBrowser/#/R-SSC-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Sus scrofa 33019 R-SSC-8852128 https://reactome.org/PathwayBrowser/#/R-SSC-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Sus scrofa 33019 R-SSC-8852131 https://reactome.org/PathwayBrowser/#/R-SSC-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Sus scrofa 33019 R-SSC-8852132 https://reactome.org/PathwayBrowser/#/R-SSC-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Sus scrofa 33019 R-SSC-8852134 https://reactome.org/PathwayBrowser/#/R-SSC-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Sus scrofa 33019 R-SSC-8875071 https://reactome.org/PathwayBrowser/#/R-SSC-8875071 ACSS3 ligates CoA to CH3COO- IEA Sus scrofa 33019 R-SSC-8939959 https://reactome.org/PathwayBrowser/#/R-SSC-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Sus scrofa 33019 R-SSC-9008822 https://reactome.org/PathwayBrowser/#/R-SSC-9008822 PPM1D dephosphorylates RUNX2 IEA Sus scrofa 33019 R-SSC-947531 https://reactome.org/PathwayBrowser/#/R-SSC-947531 Molybdenum ion transfer onto molybdopterin IEA Sus scrofa 33019 R-SSC-947535 https://reactome.org/PathwayBrowser/#/R-SSC-947535 Cyclisation of GTP to precursor Z IEA Sus scrofa 33019 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa 33019 R-SSC-9613497 https://reactome.org/PathwayBrowser/#/R-SSC-9613497 Unwinding DNA for the nascent transcript IEA Sus scrofa 33019 R-SSC-9717830 https://reactome.org/PathwayBrowser/#/R-SSC-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Sus scrofa 33019 R-SSC-9717834 https://reactome.org/PathwayBrowser/#/R-SSC-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Sus scrofa 33019 R-SSC-9731228 https://reactome.org/PathwayBrowser/#/R-SSC-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Sus scrofa 33019 R-SSC-9731590 https://reactome.org/PathwayBrowser/#/R-SSC-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Sus scrofa 33019 R-SSC-9731613 https://reactome.org/PathwayBrowser/#/R-SSC-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Sus scrofa 33019 R-SSC-9731632 https://reactome.org/PathwayBrowser/#/R-SSC-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Sus scrofa 33019 R-SSC-9734535 https://reactome.org/PathwayBrowser/#/R-SSC-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Sus scrofa 33019 R-SSC-9748951 https://reactome.org/PathwayBrowser/#/R-SSC-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Sus scrofa 33019 R-SSC-9748957 https://reactome.org/PathwayBrowser/#/R-SSC-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Sus scrofa 33019 R-SSC-9749971 https://reactome.org/PathwayBrowser/#/R-SSC-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Sus scrofa 33019 R-SSC-9750555 https://reactome.org/PathwayBrowser/#/R-SSC-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Sus scrofa 33019 R-SSC-9755030 https://reactome.org/PathwayBrowser/#/R-SSC-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Sus scrofa 33019 R-SSC-9760094 https://reactome.org/PathwayBrowser/#/R-SSC-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Sus scrofa 33019 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa 33019 R-SSC-983153 https://reactome.org/PathwayBrowser/#/R-SSC-983153 E1 mediated ubiquitin activation IEA Sus scrofa 33019 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa 33019 R-SSC-9833973 https://reactome.org/PathwayBrowser/#/R-SSC-9833973 ISGylation of PKR IEA Sus scrofa 33019 R-TAE-2408513 https://reactome.org/PathwayBrowser/#/R-TAE-2408513 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Triticum aestivum 33019 R-VRA-2408510 https://reactome.org/PathwayBrowser/#/R-VRA-2408510 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Vigna radiata var. radiata 33019 R-XTR-110311 https://reactome.org/PathwayBrowser/#/R-XTR-110311 POLZ extends translesion synthesis IEA Xenopus tropicalis 33019 R-XTR-110317 https://reactome.org/PathwayBrowser/#/R-XTR-110317 Insertion of correct bases opposite the lesion by POLH IEA Xenopus tropicalis 33019 R-XTR-110319 https://reactome.org/PathwayBrowser/#/R-XTR-110319 Elongation by POLH IEA Xenopus tropicalis 33019 R-XTR-110368 https://reactome.org/PathwayBrowser/#/R-XTR-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Xenopus tropicalis 33019 R-XTR-111253 https://reactome.org/PathwayBrowser/#/R-XTR-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Xenopus tropicalis 33019 R-XTR-111264 https://reactome.org/PathwayBrowser/#/R-XTR-111264 Addition of nucleotides between position +11 and +30 IEA Xenopus tropicalis 33019 R-XTR-111930 https://reactome.org/PathwayBrowser/#/R-XTR-111930 Adenylate cyclase produces cAMP IEA Xenopus tropicalis 33019 R-XTR-1483081 https://reactome.org/PathwayBrowser/#/R-XTR-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Xenopus tropicalis 33019 R-XTR-1483121 https://reactome.org/PathwayBrowser/#/R-XTR-1483121 PA is converted to CDP-DAG by CDS1 IEA Xenopus tropicalis 33019 R-XTR-1483165 https://reactome.org/PathwayBrowser/#/R-XTR-1483165 PA is converted to CDP-DAG by CDS2 IEA Xenopus tropicalis 33019 R-XTR-1483190 https://reactome.org/PathwayBrowser/#/R-XTR-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Xenopus tropicalis 33019 R-XTR-159425 https://reactome.org/PathwayBrowser/#/R-XTR-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 33019 R-XTR-159443 https://reactome.org/PathwayBrowser/#/R-XTR-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 33019 R-XTR-159567 https://reactome.org/PathwayBrowser/#/R-XTR-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Xenopus tropicalis 33019 R-XTR-170676 https://reactome.org/PathwayBrowser/#/R-XTR-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Xenopus tropicalis 33019 R-XTR-174124 https://reactome.org/PathwayBrowser/#/R-XTR-174124 Dephosphorylation of phospho-Cdh1 IEA Xenopus tropicalis 33019 R-XTR-174391 https://reactome.org/PathwayBrowser/#/R-XTR-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Xenopus tropicalis 33019 R-XTR-174392 https://reactome.org/PathwayBrowser/#/R-XTR-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Xenopus tropicalis 33019 R-XTR-177157 https://reactome.org/PathwayBrowser/#/R-XTR-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 33019 R-XTR-191402 https://reactome.org/PathwayBrowser/#/R-XTR-191402 Reduction of presqualene diphosphate to form squalene IEA Xenopus tropicalis 33019 R-XTR-191405 https://reactome.org/PathwayBrowser/#/R-XTR-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Xenopus tropicalis 33019 R-XTR-192137 https://reactome.org/PathwayBrowser/#/R-XTR-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 33019 R-XTR-193401 https://reactome.org/PathwayBrowser/#/R-XTR-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 33019 R-XTR-193407 https://reactome.org/PathwayBrowser/#/R-XTR-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 33019 R-XTR-193424 https://reactome.org/PathwayBrowser/#/R-XTR-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 33019 R-XTR-193711 https://reactome.org/PathwayBrowser/#/R-XTR-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 33019 R-XTR-193727 https://reactome.org/PathwayBrowser/#/R-XTR-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 33019 R-XTR-193743 https://reactome.org/PathwayBrowser/#/R-XTR-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 33019 R-XTR-193766 https://reactome.org/PathwayBrowser/#/R-XTR-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 33019 R-XTR-196753 https://reactome.org/PathwayBrowser/#/R-XTR-196753 2xPPCS ligates PPanK with Cys IEA Xenopus tropicalis 33019 R-XTR-196754 https://reactome.org/PathwayBrowser/#/R-XTR-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Xenopus tropicalis 33019 R-XTR-197250 https://reactome.org/PathwayBrowser/#/R-XTR-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Xenopus tropicalis 33019 R-XTR-197268 https://reactome.org/PathwayBrowser/#/R-XTR-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Xenopus tropicalis 33019 R-XTR-201035 https://reactome.org/PathwayBrowser/#/R-XTR-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Xenopus tropicalis 33019 R-XTR-2046085 https://reactome.org/PathwayBrowser/#/R-XTR-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Xenopus tropicalis 33019 R-XTR-2046098 https://reactome.org/PathwayBrowser/#/R-XTR-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Xenopus tropicalis 33019 R-XTR-2162192 https://reactome.org/PathwayBrowser/#/R-XTR-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Xenopus tropicalis 33019 R-XTR-2162253 https://reactome.org/PathwayBrowser/#/R-XTR-2162253 PDSS1,2 ligates FPP to IPPP IEA Xenopus tropicalis 33019 R-XTR-2395818 https://reactome.org/PathwayBrowser/#/R-XTR-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Xenopus tropicalis 33019 R-XTR-2395849 https://reactome.org/PathwayBrowser/#/R-XTR-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 33019 R-XTR-2395869 https://reactome.org/PathwayBrowser/#/R-XTR-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 33019 R-XTR-2395872 https://reactome.org/PathwayBrowser/#/R-XTR-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Xenopus tropicalis 33019 R-XTR-2408551 https://reactome.org/PathwayBrowser/#/R-XTR-2408551 SeMet is converted to AdoSeMet by MAT IEA Xenopus tropicalis 33019 R-XTR-2509827 https://reactome.org/PathwayBrowser/#/R-XTR-2509827 ITPA hydrolyses ITP to IMP IEA Xenopus tropicalis 33019 R-XTR-2509831 https://reactome.org/PathwayBrowser/#/R-XTR-2509831 ITPA hydrolyses XTP to XMP IEA Xenopus tropicalis 33019 R-XTR-2509838 https://reactome.org/PathwayBrowser/#/R-XTR-2509838 ITPA hydrolyses dITP to dIMP IEA Xenopus tropicalis 33019 R-XTR-2530501 https://reactome.org/PathwayBrowser/#/R-XTR-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Xenopus tropicalis 33019 R-XTR-2990833 https://reactome.org/PathwayBrowser/#/R-XTR-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Xenopus tropicalis 33019 R-XTR-2993447 https://reactome.org/PathwayBrowser/#/R-XTR-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Xenopus tropicalis 33019 R-XTR-2993799 https://reactome.org/PathwayBrowser/#/R-XTR-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Xenopus tropicalis 33019 R-XTR-2993802 https://reactome.org/PathwayBrowser/#/R-XTR-2993802 HLCS biotinylates PC:Mn2+ IEA Xenopus tropicalis 33019 R-XTR-2993814 https://reactome.org/PathwayBrowser/#/R-XTR-2993814 HLCS biotinylates ACACA:Mn2+ IEA Xenopus tropicalis 33019 R-XTR-2995330 https://reactome.org/PathwayBrowser/#/R-XTR-2995330 COX10 transforms heme to heme O IEA Xenopus tropicalis 33019 R-XTR-389622 https://reactome.org/PathwayBrowser/#/R-XTR-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 33019 R-XTR-389632 https://reactome.org/PathwayBrowser/#/R-XTR-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 33019 R-XTR-392513 https://reactome.org/PathwayBrowser/#/R-XTR-392513 Rap1 signal termination by Rap1GAPs IEA Xenopus tropicalis 33019 R-XTR-4084982 https://reactome.org/PathwayBrowser/#/R-XTR-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Xenopus tropicalis 33019 R-XTR-4167511 https://reactome.org/PathwayBrowser/#/R-XTR-4167511 HLCS biotinylates ACACB IEA Xenopus tropicalis 33019 R-XTR-434382 https://reactome.org/PathwayBrowser/#/R-XTR-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Xenopus tropicalis 33019 R-XTR-446204 https://reactome.org/PathwayBrowser/#/R-XTR-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Xenopus tropicalis 33019 R-XTR-449911 https://reactome.org/PathwayBrowser/#/R-XTR-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Xenopus tropicalis 33019 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 33019 R-XTR-5226964 https://reactome.org/PathwayBrowser/#/R-XTR-5226964 ANKH transports PPi from cytosol to extracellular region IEA Xenopus tropicalis 33019 R-XTR-5358475 https://reactome.org/PathwayBrowser/#/R-XTR-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Xenopus tropicalis 33019 R-XTR-548843 https://reactome.org/PathwayBrowser/#/R-XTR-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Xenopus tropicalis 33019 R-XTR-5603114 https://reactome.org/PathwayBrowser/#/R-XTR-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Xenopus tropicalis 33019 R-XTR-5610727 https://reactome.org/PathwayBrowser/#/R-XTR-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Xenopus tropicalis 33019 R-XTR-5649723 https://reactome.org/PathwayBrowser/#/R-XTR-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Xenopus tropicalis 33019 R-XTR-5649883 https://reactome.org/PathwayBrowser/#/R-XTR-5649883 POLB-mediated DNA strand displacement synthesis IEA Xenopus tropicalis 33019 R-XTR-5655892 https://reactome.org/PathwayBrowser/#/R-XTR-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Xenopus tropicalis 33019 R-XTR-5655965 https://reactome.org/PathwayBrowser/#/R-XTR-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Xenopus tropicalis 33019 R-XTR-5656148 https://reactome.org/PathwayBrowser/#/R-XTR-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Xenopus tropicalis 33019 R-XTR-5656158 https://reactome.org/PathwayBrowser/#/R-XTR-5656158 POLZ elongates POLI-incorporated dNMP IEA Xenopus tropicalis 33019 R-XTR-5687360 https://reactome.org/PathwayBrowser/#/R-XTR-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Xenopus tropicalis 33019 R-XTR-5691001 https://reactome.org/PathwayBrowser/#/R-XTR-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Xenopus tropicalis 33019 R-XTR-5694494 https://reactome.org/PathwayBrowser/#/R-XTR-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Xenopus tropicalis 33019 R-XTR-5696004 https://reactome.org/PathwayBrowser/#/R-XTR-5696004 ACSF2 ligates CoA-SH to MCFA IEA Xenopus tropicalis 33019 R-XTR-6781824 https://reactome.org/PathwayBrowser/#/R-XTR-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Xenopus tropicalis 33019 R-XTR-6782208 https://reactome.org/PathwayBrowser/#/R-XTR-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Xenopus tropicalis 33019 R-XTR-6787533 https://reactome.org/PathwayBrowser/#/R-XTR-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Xenopus tropicalis 33019 R-XTR-6788912 https://reactome.org/PathwayBrowser/#/R-XTR-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Xenopus tropicalis 33019 R-XTR-6806674 https://reactome.org/PathwayBrowser/#/R-XTR-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 33019 R-XTR-70286 https://reactome.org/PathwayBrowser/#/R-XTR-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Xenopus tropicalis 33019 R-XTR-70599 https://reactome.org/PathwayBrowser/#/R-XTR-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Xenopus tropicalis 33019 R-XTR-71732 https://reactome.org/PathwayBrowser/#/R-XTR-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Xenopus tropicalis 33019 R-XTR-71735 https://reactome.org/PathwayBrowser/#/R-XTR-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Xenopus tropicalis 33019 R-XTR-73567 https://reactome.org/PathwayBrowser/#/R-XTR-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Xenopus tropicalis 33019 R-XTR-73666 https://reactome.org/PathwayBrowser/#/R-XTR-73666 dUTP + H2O => dUMP + pyrophosphate IEA Xenopus tropicalis 33019 R-XTR-73792 https://reactome.org/PathwayBrowser/#/R-XTR-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Xenopus tropicalis 33019 R-XTR-73815 https://reactome.org/PathwayBrowser/#/R-XTR-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Xenopus tropicalis 33019 R-XTR-73932 https://reactome.org/PathwayBrowser/#/R-XTR-73932 Resynthesis of excised residue by POLB IEA Xenopus tropicalis 33019 R-XTR-74213 https://reactome.org/PathwayBrowser/#/R-XTR-74213 APRT catalyzes the conversion of adenine to AMP IEA Xenopus tropicalis 33019 R-XTR-74885 https://reactome.org/PathwayBrowser/#/R-XTR-74885 GUCYs converts GTP to cGMP IEA Xenopus tropicalis 33019 R-XTR-75850 https://reactome.org/PathwayBrowser/#/R-XTR-75850 Addition of the third nucleotide on the nascent transcript IEA Xenopus tropicalis 33019 R-XTR-75864 https://reactome.org/PathwayBrowser/#/R-XTR-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Xenopus tropicalis 33019 R-XTR-75869 https://reactome.org/PathwayBrowser/#/R-XTR-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Xenopus tropicalis 33019 R-XTR-76576 https://reactome.org/PathwayBrowser/#/R-XTR-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Xenopus tropicalis 33019 R-XTR-8852128 https://reactome.org/PathwayBrowser/#/R-XTR-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Xenopus tropicalis 33019 R-XTR-8852131 https://reactome.org/PathwayBrowser/#/R-XTR-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Xenopus tropicalis 33019 R-XTR-8852132 https://reactome.org/PathwayBrowser/#/R-XTR-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Xenopus tropicalis 33019 R-XTR-8852134 https://reactome.org/PathwayBrowser/#/R-XTR-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Xenopus tropicalis 33019 R-XTR-8875071 https://reactome.org/PathwayBrowser/#/R-XTR-8875071 ACSS3 ligates CoA to CH3COO- IEA Xenopus tropicalis 33019 R-XTR-947535 https://reactome.org/PathwayBrowser/#/R-XTR-947535 Cyclisation of GTP to precursor Z IEA Xenopus tropicalis 33019 R-XTR-9613494 https://reactome.org/PathwayBrowser/#/R-XTR-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Xenopus tropicalis 33019 R-XTR-9613497 https://reactome.org/PathwayBrowser/#/R-XTR-9613497 Unwinding DNA for the nascent transcript IEA Xenopus tropicalis 33019 R-XTR-9717830 https://reactome.org/PathwayBrowser/#/R-XTR-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Xenopus tropicalis 33019 R-XTR-9717834 https://reactome.org/PathwayBrowser/#/R-XTR-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Xenopus tropicalis 33019 R-XTR-9731228 https://reactome.org/PathwayBrowser/#/R-XTR-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Xenopus tropicalis 33019 R-XTR-9731590 https://reactome.org/PathwayBrowser/#/R-XTR-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Xenopus tropicalis 33019 R-XTR-9731613 https://reactome.org/PathwayBrowser/#/R-XTR-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Xenopus tropicalis 33019 R-XTR-9731632 https://reactome.org/PathwayBrowser/#/R-XTR-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Xenopus tropicalis 33019 R-XTR-9734535 https://reactome.org/PathwayBrowser/#/R-XTR-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Xenopus tropicalis 33019 R-XTR-9748957 https://reactome.org/PathwayBrowser/#/R-XTR-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Xenopus tropicalis 33019 R-XTR-9749971 https://reactome.org/PathwayBrowser/#/R-XTR-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Xenopus tropicalis 33019 R-XTR-9750555 https://reactome.org/PathwayBrowser/#/R-XTR-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Xenopus tropicalis 33019 R-XTR-9755030 https://reactome.org/PathwayBrowser/#/R-XTR-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Xenopus tropicalis 33019 R-XTR-983140 https://reactome.org/PathwayBrowser/#/R-XTR-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Xenopus tropicalis 33019 R-XTR-983153 https://reactome.org/PathwayBrowser/#/R-XTR-983153 E1 mediated ubiquitin activation IEA Xenopus tropicalis 33019 R-XTR-983156 https://reactome.org/PathwayBrowser/#/R-XTR-983156 Polyubiquitination of substrate IEA Xenopus tropicalis 33101 R-BTA-8933635 https://reactome.org/PathwayBrowser/#/R-BTA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Bos taurus 33101 R-BTA-9854368 https://reactome.org/PathwayBrowser/#/R-BTA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Bos taurus 33101 R-CEL-8933635 https://reactome.org/PathwayBrowser/#/R-CEL-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Caenorhabditis elegans 33101 R-CEL-9854368 https://reactome.org/PathwayBrowser/#/R-CEL-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Caenorhabditis elegans 33101 R-CFA-8933635 https://reactome.org/PathwayBrowser/#/R-CFA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Canis familiaris 33101 R-CFA-9854368 https://reactome.org/PathwayBrowser/#/R-CFA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Canis familiaris 33101 R-DDI-8933635 https://reactome.org/PathwayBrowser/#/R-DDI-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Dictyostelium discoideum 33101 R-DDI-9854368 https://reactome.org/PathwayBrowser/#/R-DDI-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Dictyostelium discoideum 33101 R-DME-8933635 https://reactome.org/PathwayBrowser/#/R-DME-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Drosophila melanogaster 33101 R-DME-9854368 https://reactome.org/PathwayBrowser/#/R-DME-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Drosophila melanogaster 33101 R-DRE-9854368 https://reactome.org/PathwayBrowser/#/R-DRE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Danio rerio 33101 R-GGA-8933635 https://reactome.org/PathwayBrowser/#/R-GGA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Gallus gallus 33101 R-GGA-9854368 https://reactome.org/PathwayBrowser/#/R-GGA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Gallus gallus 33101 R-HSA-1500761 https://reactome.org/PathwayBrowser/#/R-HSA-1500761 Nitrogen dioxide is reduced to NO by F420 TAS Homo sapiens 33101 R-HSA-6803989 https://reactome.org/PathwayBrowser/#/R-HSA-6803989 Nitric oxide and O2 react to NO2 TAS Homo sapiens 33101 R-HSA-6804006 https://reactome.org/PathwayBrowser/#/R-HSA-6804006 NO and NO2 react to N2O3 TAS Homo sapiens 33101 R-HSA-8933635 https://reactome.org/PathwayBrowser/#/R-HSA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide TAS Homo sapiens 33101 R-HSA-9854368 https://reactome.org/PathwayBrowser/#/R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S TAS Homo sapiens 33101 R-MMU-8933635 https://reactome.org/PathwayBrowser/#/R-MMU-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Mus musculus 33101 R-MMU-9854368 https://reactome.org/PathwayBrowser/#/R-MMU-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Mus musculus 33101 R-RNO-8933635 https://reactome.org/PathwayBrowser/#/R-RNO-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Rattus norvegicus 33101 R-RNO-9854368 https://reactome.org/PathwayBrowser/#/R-RNO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Rattus norvegicus 33101 R-SCE-9854368 https://reactome.org/PathwayBrowser/#/R-SCE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Saccharomyces cerevisiae 33101 R-SPO-9854368 https://reactome.org/PathwayBrowser/#/R-SPO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Schizosaccharomyces pombe 33101 R-SSC-8933635 https://reactome.org/PathwayBrowser/#/R-SSC-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Sus scrofa 33101 R-SSC-9854368 https://reactome.org/PathwayBrowser/#/R-SSC-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Sus scrofa 33101 R-XTR-9854368 https://reactome.org/PathwayBrowser/#/R-XTR-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Xenopus tropicalis 33184 R-BTA-5690042 https://reactome.org/PathwayBrowser/#/R-BTA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 33184 R-BTA-5690043 https://reactome.org/PathwayBrowser/#/R-BTA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 33184 R-BTA-5690066 https://reactome.org/PathwayBrowser/#/R-BTA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 33184 R-BTA-8848246 https://reactome.org/PathwayBrowser/#/R-BTA-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Bos taurus 33184 R-BTA-8848247 https://reactome.org/PathwayBrowser/#/R-BTA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Bos taurus 33184 R-BTA-8848250 https://reactome.org/PathwayBrowser/#/R-BTA-8848250 ACBD6 binds LCFA-CoA IEA Bos taurus 33184 R-CEL-5690042 https://reactome.org/PathwayBrowser/#/R-CEL-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 33184 R-CEL-5690043 https://reactome.org/PathwayBrowser/#/R-CEL-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 33184 R-CEL-5690066 https://reactome.org/PathwayBrowser/#/R-CEL-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 33184 R-CEL-8848247 https://reactome.org/PathwayBrowser/#/R-CEL-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Caenorhabditis elegans 33184 R-CEL-8848250 https://reactome.org/PathwayBrowser/#/R-CEL-8848250 ACBD6 binds LCFA-CoA IEA Caenorhabditis elegans 33184 R-CFA-5690042 https://reactome.org/PathwayBrowser/#/R-CFA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 33184 R-CFA-5690043 https://reactome.org/PathwayBrowser/#/R-CFA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 33184 R-CFA-5690066 https://reactome.org/PathwayBrowser/#/R-CFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 33184 R-CFA-8848246 https://reactome.org/PathwayBrowser/#/R-CFA-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Canis familiaris 33184 R-CFA-8848247 https://reactome.org/PathwayBrowser/#/R-CFA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Canis familiaris 33184 R-CFA-8848250 https://reactome.org/PathwayBrowser/#/R-CFA-8848250 ACBD6 binds LCFA-CoA IEA Canis familiaris 33184 R-DDI-5690043 https://reactome.org/PathwayBrowser/#/R-DDI-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 33184 R-DDI-5690066 https://reactome.org/PathwayBrowser/#/R-DDI-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 33184 R-DDI-8848246 https://reactome.org/PathwayBrowser/#/R-DDI-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Dictyostelium discoideum 33184 R-DDI-8848250 https://reactome.org/PathwayBrowser/#/R-DDI-8848250 ACBD6 binds LCFA-CoA IEA Dictyostelium discoideum 33184 R-DME-5690043 https://reactome.org/PathwayBrowser/#/R-DME-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 33184 R-DME-5690066 https://reactome.org/PathwayBrowser/#/R-DME-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 33184 R-DME-8848246 https://reactome.org/PathwayBrowser/#/R-DME-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Drosophila melanogaster 33184 R-DME-8848247 https://reactome.org/PathwayBrowser/#/R-DME-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Drosophila melanogaster 33184 R-DME-8848250 https://reactome.org/PathwayBrowser/#/R-DME-8848250 ACBD6 binds LCFA-CoA IEA Drosophila melanogaster 33184 R-DRE-5690042 https://reactome.org/PathwayBrowser/#/R-DRE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 33184 R-DRE-5690066 https://reactome.org/PathwayBrowser/#/R-DRE-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 33184 R-DRE-8848246 https://reactome.org/PathwayBrowser/#/R-DRE-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Danio rerio 33184 R-DRE-8848247 https://reactome.org/PathwayBrowser/#/R-DRE-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Danio rerio 33184 R-DRE-8848250 https://reactome.org/PathwayBrowser/#/R-DRE-8848250 ACBD6 binds LCFA-CoA IEA Danio rerio 33184 R-GGA-5690042 https://reactome.org/PathwayBrowser/#/R-GGA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 33184 R-GGA-5690043 https://reactome.org/PathwayBrowser/#/R-GGA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 33184 R-GGA-5690066 https://reactome.org/PathwayBrowser/#/R-GGA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 33184 R-GGA-8848246 https://reactome.org/PathwayBrowser/#/R-GGA-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Gallus gallus 33184 R-GGA-8848247 https://reactome.org/PathwayBrowser/#/R-GGA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Gallus gallus 33184 R-GGA-8848250 https://reactome.org/PathwayBrowser/#/R-GGA-8848250 ACBD6 binds LCFA-CoA IEA Gallus gallus 33184 R-HSA-5690042 https://reactome.org/PathwayBrowser/#/R-HSA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 33184 R-HSA-5690043 https://reactome.org/PathwayBrowser/#/R-HSA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 33184 R-HSA-5690066 https://reactome.org/PathwayBrowser/#/R-HSA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 33184 R-HSA-8848246 https://reactome.org/PathwayBrowser/#/R-HSA-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA TAS Homo sapiens 33184 R-HSA-8848247 https://reactome.org/PathwayBrowser/#/R-HSA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA TAS Homo sapiens 33184 R-HSA-8848250 https://reactome.org/PathwayBrowser/#/R-HSA-8848250 ACBD6 binds LCFA-CoA TAS Homo sapiens 33184 R-MMU-5690042 https://reactome.org/PathwayBrowser/#/R-MMU-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 33184 R-MMU-5690043 https://reactome.org/PathwayBrowser/#/R-MMU-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 33184 R-MMU-5690066 https://reactome.org/PathwayBrowser/#/R-MMU-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 33184 R-MMU-8848246 https://reactome.org/PathwayBrowser/#/R-MMU-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Mus musculus 33184 R-MMU-8848247 https://reactome.org/PathwayBrowser/#/R-MMU-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Mus musculus 33184 R-MMU-8848250 https://reactome.org/PathwayBrowser/#/R-MMU-8848250 ACBD6 binds LCFA-CoA IEA Mus musculus 33184 R-PFA-5690066 https://reactome.org/PathwayBrowser/#/R-PFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Plasmodium falciparum 33184 R-PFA-8848246 https://reactome.org/PathwayBrowser/#/R-PFA-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Plasmodium falciparum 33184 R-PFA-8848247 https://reactome.org/PathwayBrowser/#/R-PFA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Plasmodium falciparum 33184 R-PFA-8848250 https://reactome.org/PathwayBrowser/#/R-PFA-8848250 ACBD6 binds LCFA-CoA IEA Plasmodium falciparum 33184 R-RNO-5690042 https://reactome.org/PathwayBrowser/#/R-RNO-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 33184 R-RNO-5690043 https://reactome.org/PathwayBrowser/#/R-RNO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 33184 R-RNO-5690066 https://reactome.org/PathwayBrowser/#/R-RNO-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 33184 R-RNO-8848246 https://reactome.org/PathwayBrowser/#/R-RNO-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Rattus norvegicus 33184 R-RNO-8848247 https://reactome.org/PathwayBrowser/#/R-RNO-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Rattus norvegicus 33184 R-RNO-8848250 https://reactome.org/PathwayBrowser/#/R-RNO-8848250 ACBD6 binds LCFA-CoA IEA Rattus norvegicus 33184 R-SCE-5690042 https://reactome.org/PathwayBrowser/#/R-SCE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Saccharomyces cerevisiae 33184 R-SCE-8848246 https://reactome.org/PathwayBrowser/#/R-SCE-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Saccharomyces cerevisiae 33184 R-SPO-5690043 https://reactome.org/PathwayBrowser/#/R-SPO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Schizosaccharomyces pombe 33184 R-SPO-8848246 https://reactome.org/PathwayBrowser/#/R-SPO-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Schizosaccharomyces pombe 33184 R-SSC-5690042 https://reactome.org/PathwayBrowser/#/R-SSC-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 33184 R-SSC-5690043 https://reactome.org/PathwayBrowser/#/R-SSC-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 33184 R-SSC-5690066 https://reactome.org/PathwayBrowser/#/R-SSC-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 33184 R-SSC-8848246 https://reactome.org/PathwayBrowser/#/R-SSC-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Sus scrofa 33184 R-SSC-8848247 https://reactome.org/PathwayBrowser/#/R-SSC-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Sus scrofa 33184 R-SSC-8848250 https://reactome.org/PathwayBrowser/#/R-SSC-8848250 ACBD6 binds LCFA-CoA IEA Sus scrofa 33184 R-XTR-5690042 https://reactome.org/PathwayBrowser/#/R-XTR-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 33184 R-XTR-5690043 https://reactome.org/PathwayBrowser/#/R-XTR-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 33184 R-XTR-5690066 https://reactome.org/PathwayBrowser/#/R-XTR-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 33184 R-XTR-8848246 https://reactome.org/PathwayBrowser/#/R-XTR-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Xenopus tropicalis 33184 R-XTR-8848247 https://reactome.org/PathwayBrowser/#/R-XTR-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Xenopus tropicalis 33184 R-XTR-8848250 https://reactome.org/PathwayBrowser/#/R-XTR-8848250 ACBD6 binds LCFA-CoA IEA Xenopus tropicalis 33190 R-HSA-909776 https://reactome.org/PathwayBrowser/#/R-HSA-909776 beta-alanine + pyruvate => 3-oxopropanoate + alanine IEA Homo sapiens 33190 R-RNO-909762 https://reactome.org/PathwayBrowser/#/R-RNO-909762 beta-alanine + pyruvate => 3-oxopropanoate + alanine TAS Rattus norvegicus 33384 R-BTA-1483089 https://reactome.org/PathwayBrowser/#/R-BTA-1483089 PE is converted to PS by PTDSS2 IEA Bos taurus 33384 R-BTA-1483186 https://reactome.org/PathwayBrowser/#/R-BTA-1483186 PC is converted to PS by PTDSS1 IEA Bos taurus 33384 R-BTA-1614524 https://reactome.org/PathwayBrowser/#/R-BTA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Bos taurus 33384 R-BTA-1614614 https://reactome.org/PathwayBrowser/#/R-BTA-1614614 Cysteine is degraded to serine and H2S IEA Bos taurus 33384 R-BTA-200651 https://reactome.org/PathwayBrowser/#/R-BTA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Bos taurus 33384 R-BTA-200735 https://reactome.org/PathwayBrowser/#/R-BTA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Bos taurus 33384 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 33384 R-BTA-352108 https://reactome.org/PathwayBrowser/#/R-BTA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Bos taurus 33384 R-BTA-352119 https://reactome.org/PathwayBrowser/#/R-BTA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Bos taurus 33384 R-BTA-352182 https://reactome.org/PathwayBrowser/#/R-BTA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Bos taurus 33384 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 33384 R-BTA-352347 https://reactome.org/PathwayBrowser/#/R-BTA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Bos taurus 33384 R-BTA-352354 https://reactome.org/PathwayBrowser/#/R-BTA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Bos taurus 33384 R-BTA-352364 https://reactome.org/PathwayBrowser/#/R-BTA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Bos taurus 33384 R-BTA-352371 https://reactome.org/PathwayBrowser/#/R-BTA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Bos taurus 33384 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 33384 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 33384 R-BTA-376200 https://reactome.org/PathwayBrowser/#/R-BTA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Bos taurus 33384 R-BTA-428127 https://reactome.org/PathwayBrowser/#/R-BTA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Bos taurus 33384 R-BTA-5694137 https://reactome.org/PathwayBrowser/#/R-BTA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Bos taurus 33384 R-BTA-8932980 https://reactome.org/PathwayBrowser/#/R-BTA-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Bos taurus 33384 R-BTA-9014766 https://reactome.org/PathwayBrowser/#/R-BTA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Bos taurus 33384 R-BTA-9034539 https://reactome.org/PathwayBrowser/#/R-BTA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Bos taurus 33384 R-BTA-977324 https://reactome.org/PathwayBrowser/#/R-BTA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Bos taurus 33384 R-CEL-1483186 https://reactome.org/PathwayBrowser/#/R-CEL-1483186 PC is converted to PS by PTDSS1 IEA Caenorhabditis elegans 33384 R-CEL-1614524 https://reactome.org/PathwayBrowser/#/R-CEL-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Caenorhabditis elegans 33384 R-CEL-1614614 https://reactome.org/PathwayBrowser/#/R-CEL-1614614 Cysteine is degraded to serine and H2S IEA Caenorhabditis elegans 33384 R-CEL-200651 https://reactome.org/PathwayBrowser/#/R-CEL-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Caenorhabditis elegans 33384 R-CEL-200735 https://reactome.org/PathwayBrowser/#/R-CEL-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Caenorhabditis elegans 33384 R-CEL-352347 https://reactome.org/PathwayBrowser/#/R-CEL-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Caenorhabditis elegans 33384 R-CEL-352354 https://reactome.org/PathwayBrowser/#/R-CEL-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Caenorhabditis elegans 33384 R-CEL-352364 https://reactome.org/PathwayBrowser/#/R-CEL-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Caenorhabditis elegans 33384 R-CEL-352371 https://reactome.org/PathwayBrowser/#/R-CEL-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Caenorhabditis elegans 33384 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 33384 R-CEL-8932980 https://reactome.org/PathwayBrowser/#/R-CEL-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Caenorhabditis elegans 33384 R-CEL-9014766 https://reactome.org/PathwayBrowser/#/R-CEL-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Caenorhabditis elegans 33384 R-CEL-9034539 https://reactome.org/PathwayBrowser/#/R-CEL-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Caenorhabditis elegans 33384 R-CEL-977324 https://reactome.org/PathwayBrowser/#/R-CEL-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Caenorhabditis elegans 33384 R-CFA-1483089 https://reactome.org/PathwayBrowser/#/R-CFA-1483089 PE is converted to PS by PTDSS2 IEA Canis familiaris 33384 R-CFA-1483186 https://reactome.org/PathwayBrowser/#/R-CFA-1483186 PC is converted to PS by PTDSS1 IEA Canis familiaris 33384 R-CFA-1614524 https://reactome.org/PathwayBrowser/#/R-CFA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Canis familiaris 33384 R-CFA-1614614 https://reactome.org/PathwayBrowser/#/R-CFA-1614614 Cysteine is degraded to serine and H2S IEA Canis familiaris 33384 R-CFA-200651 https://reactome.org/PathwayBrowser/#/R-CFA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Canis familiaris 33384 R-CFA-200735 https://reactome.org/PathwayBrowser/#/R-CFA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Canis familiaris 33384 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 33384 R-CFA-352108 https://reactome.org/PathwayBrowser/#/R-CFA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Canis familiaris 33384 R-CFA-352119 https://reactome.org/PathwayBrowser/#/R-CFA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Canis familiaris 33384 R-CFA-352182 https://reactome.org/PathwayBrowser/#/R-CFA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Canis familiaris 33384 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 33384 R-CFA-352347 https://reactome.org/PathwayBrowser/#/R-CFA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Canis familiaris 33384 R-CFA-352354 https://reactome.org/PathwayBrowser/#/R-CFA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Canis familiaris 33384 R-CFA-352364 https://reactome.org/PathwayBrowser/#/R-CFA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Canis familiaris 33384 R-CFA-352371 https://reactome.org/PathwayBrowser/#/R-CFA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Canis familiaris 33384 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 33384 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 33384 R-CFA-376200 https://reactome.org/PathwayBrowser/#/R-CFA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Canis familiaris 33384 R-CFA-428127 https://reactome.org/PathwayBrowser/#/R-CFA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Canis familiaris 33384 R-CFA-5694137 https://reactome.org/PathwayBrowser/#/R-CFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Canis familiaris 33384 R-CFA-8932980 https://reactome.org/PathwayBrowser/#/R-CFA-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Canis familiaris 33384 R-CFA-9014766 https://reactome.org/PathwayBrowser/#/R-CFA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Canis familiaris 33384 R-CFA-9034539 https://reactome.org/PathwayBrowser/#/R-CFA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Canis familiaris 33384 R-CFA-977324 https://reactome.org/PathwayBrowser/#/R-CFA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Canis familiaris 33384 R-DDI-1483089 https://reactome.org/PathwayBrowser/#/R-DDI-1483089 PE is converted to PS by PTDSS2 IEA Dictyostelium discoideum 33384 R-DDI-1483186 https://reactome.org/PathwayBrowser/#/R-DDI-1483186 PC is converted to PS by PTDSS1 IEA Dictyostelium discoideum 33384 R-DDI-1614524 https://reactome.org/PathwayBrowser/#/R-DDI-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Dictyostelium discoideum 33384 R-DDI-1614614 https://reactome.org/PathwayBrowser/#/R-DDI-1614614 Cysteine is degraded to serine and H2S IEA Dictyostelium discoideum 33384 R-DDI-200651 https://reactome.org/PathwayBrowser/#/R-DDI-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Dictyostelium discoideum 33384 R-DDI-200735 https://reactome.org/PathwayBrowser/#/R-DDI-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Dictyostelium discoideum 33384 R-DDI-5694137 https://reactome.org/PathwayBrowser/#/R-DDI-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Dictyostelium discoideum 33384 R-DDI-8932980 https://reactome.org/PathwayBrowser/#/R-DDI-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Dictyostelium discoideum 33384 R-DDI-9014766 https://reactome.org/PathwayBrowser/#/R-DDI-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Dictyostelium discoideum 33384 R-DDI-9034539 https://reactome.org/PathwayBrowser/#/R-DDI-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Dictyostelium discoideum 33384 R-DDI-977324 https://reactome.org/PathwayBrowser/#/R-DDI-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Dictyostelium discoideum 33384 R-DME-1483186 https://reactome.org/PathwayBrowser/#/R-DME-1483186 PC is converted to PS by PTDSS1 IEA Drosophila melanogaster 33384 R-DME-1614524 https://reactome.org/PathwayBrowser/#/R-DME-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Drosophila melanogaster 33384 R-DME-1614614 https://reactome.org/PathwayBrowser/#/R-DME-1614614 Cysteine is degraded to serine and H2S IEA Drosophila melanogaster 33384 R-DME-200651 https://reactome.org/PathwayBrowser/#/R-DME-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Drosophila melanogaster 33384 R-DME-200735 https://reactome.org/PathwayBrowser/#/R-DME-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Drosophila melanogaster 33384 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 33384 R-DME-352108 https://reactome.org/PathwayBrowser/#/R-DME-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 33384 R-DME-352119 https://reactome.org/PathwayBrowser/#/R-DME-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 33384 R-DME-352182 https://reactome.org/PathwayBrowser/#/R-DME-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Drosophila melanogaster 33384 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 33384 R-DME-352347 https://reactome.org/PathwayBrowser/#/R-DME-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Drosophila melanogaster 33384 R-DME-352354 https://reactome.org/PathwayBrowser/#/R-DME-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Drosophila melanogaster 33384 R-DME-352364 https://reactome.org/PathwayBrowser/#/R-DME-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Drosophila melanogaster 33384 R-DME-352371 https://reactome.org/PathwayBrowser/#/R-DME-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Drosophila melanogaster 33384 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 33384 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 33384 R-DME-376200 https://reactome.org/PathwayBrowser/#/R-DME-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Drosophila melanogaster 33384 R-DME-428127 https://reactome.org/PathwayBrowser/#/R-DME-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Drosophila melanogaster 33384 R-DME-8932980 https://reactome.org/PathwayBrowser/#/R-DME-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Drosophila melanogaster 33384 R-DME-977324 https://reactome.org/PathwayBrowser/#/R-DME-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Drosophila melanogaster 33384 R-DRE-1483089 https://reactome.org/PathwayBrowser/#/R-DRE-1483089 PE is converted to PS by PTDSS2 IEA Danio rerio 33384 R-DRE-1483186 https://reactome.org/PathwayBrowser/#/R-DRE-1483186 PC is converted to PS by PTDSS1 IEA Danio rerio 33384 R-DRE-1614524 https://reactome.org/PathwayBrowser/#/R-DRE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Danio rerio 33384 R-DRE-1614614 https://reactome.org/PathwayBrowser/#/R-DRE-1614614 Cysteine is degraded to serine and H2S IEA Danio rerio 33384 R-DRE-200651 https://reactome.org/PathwayBrowser/#/R-DRE-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Danio rerio 33384 R-DRE-200735 https://reactome.org/PathwayBrowser/#/R-DRE-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Danio rerio 33384 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 33384 R-DRE-352108 https://reactome.org/PathwayBrowser/#/R-DRE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Danio rerio 33384 R-DRE-352182 https://reactome.org/PathwayBrowser/#/R-DRE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Danio rerio 33384 R-DRE-352347 https://reactome.org/PathwayBrowser/#/R-DRE-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Danio rerio 33384 R-DRE-352354 https://reactome.org/PathwayBrowser/#/R-DRE-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Danio rerio 33384 R-DRE-352364 https://reactome.org/PathwayBrowser/#/R-DRE-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Danio rerio 33384 R-DRE-352371 https://reactome.org/PathwayBrowser/#/R-DRE-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Danio rerio 33384 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 33384 R-DRE-428127 https://reactome.org/PathwayBrowser/#/R-DRE-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Danio rerio 33384 R-DRE-5694137 https://reactome.org/PathwayBrowser/#/R-DRE-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Danio rerio 33384 R-DRE-8932980 https://reactome.org/PathwayBrowser/#/R-DRE-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Danio rerio 33384 R-DRE-977324 https://reactome.org/PathwayBrowser/#/R-DRE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Danio rerio 33384 R-GGA-1483089 https://reactome.org/PathwayBrowser/#/R-GGA-1483089 PE is converted to PS by PTDSS2 IEA Gallus gallus 33384 R-GGA-1483186 https://reactome.org/PathwayBrowser/#/R-GGA-1483186 PC is converted to PS by PTDSS1 IEA Gallus gallus 33384 R-GGA-1614524 https://reactome.org/PathwayBrowser/#/R-GGA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Gallus gallus 33384 R-GGA-1614614 https://reactome.org/PathwayBrowser/#/R-GGA-1614614 Cysteine is degraded to serine and H2S IEA Gallus gallus 33384 R-GGA-200651 https://reactome.org/PathwayBrowser/#/R-GGA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Gallus gallus 33384 R-GGA-200735 https://reactome.org/PathwayBrowser/#/R-GGA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Gallus gallus 33384 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 33384 R-GGA-352108 https://reactome.org/PathwayBrowser/#/R-GGA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Gallus gallus 33384 R-GGA-352119 https://reactome.org/PathwayBrowser/#/R-GGA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Gallus gallus 33384 R-GGA-352347 https://reactome.org/PathwayBrowser/#/R-GGA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Gallus gallus 33384 R-GGA-352354 https://reactome.org/PathwayBrowser/#/R-GGA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Gallus gallus 33384 R-GGA-352364 https://reactome.org/PathwayBrowser/#/R-GGA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Gallus gallus 33384 R-GGA-352371 https://reactome.org/PathwayBrowser/#/R-GGA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Gallus gallus 33384 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 33384 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 33384 R-GGA-428127 https://reactome.org/PathwayBrowser/#/R-GGA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Gallus gallus 33384 R-GGA-433550 https://reactome.org/PathwayBrowser/#/R-GGA-433550 palmitoyl-CoA + serine => 3-dehydrosphinganine + CoASH + CO2 IEA Gallus gallus 33384 R-GGA-8932980 https://reactome.org/PathwayBrowser/#/R-GGA-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Gallus gallus 33384 R-GGA-9014766 https://reactome.org/PathwayBrowser/#/R-GGA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Gallus gallus 33384 R-GGA-9034539 https://reactome.org/PathwayBrowser/#/R-GGA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Gallus gallus 33384 R-GGA-977324 https://reactome.org/PathwayBrowser/#/R-GGA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Gallus gallus 33384 R-HSA-1483089 https://reactome.org/PathwayBrowser/#/R-HSA-1483089 PE is converted to PS by PTDSS2 TAS Homo sapiens 33384 R-HSA-1483186 https://reactome.org/PathwayBrowser/#/R-HSA-1483186 PC is converted to PS by PTDSS1 TAS Homo sapiens 33384 R-HSA-1614524 https://reactome.org/PathwayBrowser/#/R-HSA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine TAS Homo sapiens 33384 R-HSA-1614614 https://reactome.org/PathwayBrowser/#/R-HSA-1614614 Cysteine is degraded to serine and H2S TAS Homo sapiens 33384 R-HSA-200651 https://reactome.org/PathwayBrowser/#/R-HSA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine TAS Homo sapiens 33384 R-HSA-200735 https://reactome.org/PathwayBrowser/#/R-HSA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG TAS Homo sapiens 33384 R-HSA-2408526 https://reactome.org/PathwayBrowser/#/R-HSA-2408526 tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer TAS Homo sapiens 33384 R-HSA-2408559 https://reactome.org/PathwayBrowser/#/R-HSA-2408559 SeHCys and Ser are dehydrated into SeCysta by CBS IEA Homo sapiens 33384 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 33384 R-HSA-352108 https://reactome.org/PathwayBrowser/#/R-HSA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids TAS Homo sapiens 33384 R-HSA-352119 https://reactome.org/PathwayBrowser/#/R-HSA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids TAS Homo sapiens 33384 R-HSA-352182 https://reactome.org/PathwayBrowser/#/R-HSA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine TAS Homo sapiens 33384 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 33384 R-HSA-352347 https://reactome.org/PathwayBrowser/#/R-HSA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine TAS Homo sapiens 33384 R-HSA-352354 https://reactome.org/PathwayBrowser/#/R-HSA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine TAS Homo sapiens 33384 R-HSA-352364 https://reactome.org/PathwayBrowser/#/R-HSA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine TAS Homo sapiens 33384 R-HSA-352371 https://reactome.org/PathwayBrowser/#/R-HSA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine TAS Homo sapiens 33384 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 33384 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 33384 R-HSA-376200 https://reactome.org/PathwayBrowser/#/R-HSA-376200 SLC7A10-mediated uptake of small neutral amino acids TAS Homo sapiens 33384 R-HSA-379992 https://reactome.org/PathwayBrowser/#/R-HSA-379992 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 33384 R-HSA-380239 https://reactome.org/PathwayBrowser/#/R-HSA-380239 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 33384 R-HSA-428127 https://reactome.org/PathwayBrowser/#/R-HSA-428127 SPTLC complexes transfer acyl-CoA onto serine TAS Homo sapiens 33384 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 33384 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 33384 R-HSA-5694137 https://reactome.org/PathwayBrowser/#/R-HSA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser TAS Homo sapiens 33384 R-HSA-8932980 https://reactome.org/PathwayBrowser/#/R-HSA-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane TAS Homo sapiens 33384 R-HSA-9014766 https://reactome.org/PathwayBrowser/#/R-HSA-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser TAS Homo sapiens 33384 R-HSA-9034539 https://reactome.org/PathwayBrowser/#/R-HSA-9034539 PXLP-K56-SRR dimer deaminates L-Ser TAS Homo sapiens 33384 R-HSA-977324 https://reactome.org/PathwayBrowser/#/R-HSA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser TAS Homo sapiens 33384 R-MMU-1483089 https://reactome.org/PathwayBrowser/#/R-MMU-1483089 PE is converted to PS by PTDSS2 IEA Mus musculus 33384 R-MMU-1483186 https://reactome.org/PathwayBrowser/#/R-MMU-1483186 PC is converted to PS by PTDSS1 IEA Mus musculus 33384 R-MMU-1614524 https://reactome.org/PathwayBrowser/#/R-MMU-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Mus musculus 33384 R-MMU-1614614 https://reactome.org/PathwayBrowser/#/R-MMU-1614614 Cysteine is degraded to serine and H2S IEA Mus musculus 33384 R-MMU-200651 https://reactome.org/PathwayBrowser/#/R-MMU-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Mus musculus 33384 R-MMU-200735 https://reactome.org/PathwayBrowser/#/R-MMU-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Mus musculus 33384 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 33384 R-MMU-352108 https://reactome.org/PathwayBrowser/#/R-MMU-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Mus musculus 33384 R-MMU-352119 https://reactome.org/PathwayBrowser/#/R-MMU-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Mus musculus 33384 R-MMU-352182 https://reactome.org/PathwayBrowser/#/R-MMU-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Mus musculus 33384 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 33384 R-MMU-352347 https://reactome.org/PathwayBrowser/#/R-MMU-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Mus musculus 33384 R-MMU-352354 https://reactome.org/PathwayBrowser/#/R-MMU-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Mus musculus 33384 R-MMU-352364 https://reactome.org/PathwayBrowser/#/R-MMU-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Mus musculus 33384 R-MMU-352371 https://reactome.org/PathwayBrowser/#/R-MMU-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Mus musculus 33384 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 33384 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 33384 R-MMU-376200 https://reactome.org/PathwayBrowser/#/R-MMU-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Mus musculus 33384 R-MMU-428127 https://reactome.org/PathwayBrowser/#/R-MMU-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Mus musculus 33384 R-MMU-5694137 https://reactome.org/PathwayBrowser/#/R-MMU-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Mus musculus 33384 R-MMU-8932980 https://reactome.org/PathwayBrowser/#/R-MMU-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Mus musculus 33384 R-MMU-9014766 https://reactome.org/PathwayBrowser/#/R-MMU-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Mus musculus 33384 R-MMU-9034539 https://reactome.org/PathwayBrowser/#/R-MMU-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Mus musculus 33384 R-MMU-977324 https://reactome.org/PathwayBrowser/#/R-MMU-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Mus musculus 33384 R-MTU-936615 https://reactome.org/PathwayBrowser/#/R-MTU-936615 acetylation of serine TAS Mycobacterium tuberculosis 33384 R-PFA-1483089 https://reactome.org/PathwayBrowser/#/R-PFA-1483089 PE is converted to PS by PTDSS2 IEA Plasmodium falciparum 33384 R-PFA-1483186 https://reactome.org/PathwayBrowser/#/R-PFA-1483186 PC is converted to PS by PTDSS1 IEA Plasmodium falciparum 33384 R-PFA-200651 https://reactome.org/PathwayBrowser/#/R-PFA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Plasmodium falciparum 33384 R-PFA-200735 https://reactome.org/PathwayBrowser/#/R-PFA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Plasmodium falciparum 33384 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 33384 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 33384 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 33384 R-PFA-5694137 https://reactome.org/PathwayBrowser/#/R-PFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Plasmodium falciparum 33384 R-RNO-1483089 https://reactome.org/PathwayBrowser/#/R-RNO-1483089 PE is converted to PS by PTDSS2 IEA Rattus norvegicus 33384 R-RNO-1483186 https://reactome.org/PathwayBrowser/#/R-RNO-1483186 PC is converted to PS by PTDSS1 IEA Rattus norvegicus 33384 R-RNO-1614524 https://reactome.org/PathwayBrowser/#/R-RNO-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Rattus norvegicus 33384 R-RNO-1614614 https://reactome.org/PathwayBrowser/#/R-RNO-1614614 Cysteine is degraded to serine and H2S IEA Rattus norvegicus 33384 R-RNO-200651 https://reactome.org/PathwayBrowser/#/R-RNO-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Rattus norvegicus 33384 R-RNO-200735 https://reactome.org/PathwayBrowser/#/R-RNO-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Rattus norvegicus 33384 R-RNO-2408533 https://reactome.org/PathwayBrowser/#/R-RNO-2408533 SeHCys and Ser are dehydrated into SeCysta by Cbs TAS Rattus norvegicus 33384 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 33384 R-RNO-352108 https://reactome.org/PathwayBrowser/#/R-RNO-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Rattus norvegicus 33384 R-RNO-352119 https://reactome.org/PathwayBrowser/#/R-RNO-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Rattus norvegicus 33384 R-RNO-352182 https://reactome.org/PathwayBrowser/#/R-RNO-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Rattus norvegicus 33384 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 33384 R-RNO-352347 https://reactome.org/PathwayBrowser/#/R-RNO-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Rattus norvegicus 33384 R-RNO-352354 https://reactome.org/PathwayBrowser/#/R-RNO-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Rattus norvegicus 33384 R-RNO-352364 https://reactome.org/PathwayBrowser/#/R-RNO-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Rattus norvegicus 33384 R-RNO-352371 https://reactome.org/PathwayBrowser/#/R-RNO-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Rattus norvegicus 33384 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 33384 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 33384 R-RNO-376200 https://reactome.org/PathwayBrowser/#/R-RNO-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Rattus norvegicus 33384 R-RNO-428127 https://reactome.org/PathwayBrowser/#/R-RNO-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Rattus norvegicus 33384 R-RNO-5694137 https://reactome.org/PathwayBrowser/#/R-RNO-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Rattus norvegicus 33384 R-RNO-8932980 https://reactome.org/PathwayBrowser/#/R-RNO-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Rattus norvegicus 33384 R-RNO-9014766 https://reactome.org/PathwayBrowser/#/R-RNO-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Rattus norvegicus 33384 R-RNO-9034539 https://reactome.org/PathwayBrowser/#/R-RNO-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Rattus norvegicus 33384 R-RNO-977324 https://reactome.org/PathwayBrowser/#/R-RNO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Rattus norvegicus 33384 R-SCE-1614524 https://reactome.org/PathwayBrowser/#/R-SCE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Saccharomyces cerevisiae 33384 R-SCE-1614614 https://reactome.org/PathwayBrowser/#/R-SCE-1614614 Cysteine is degraded to serine and H2S IEA Saccharomyces cerevisiae 33384 R-SCE-352108 https://reactome.org/PathwayBrowser/#/R-SCE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 33384 R-SCE-352119 https://reactome.org/PathwayBrowser/#/R-SCE-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 33384 R-SCE-352182 https://reactome.org/PathwayBrowser/#/R-SCE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Saccharomyces cerevisiae 33384 R-SCE-8932980 https://reactome.org/PathwayBrowser/#/R-SCE-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Saccharomyces cerevisiae 33384 R-SCE-9014766 https://reactome.org/PathwayBrowser/#/R-SCE-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Saccharomyces cerevisiae 33384 R-SCE-9034539 https://reactome.org/PathwayBrowser/#/R-SCE-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Saccharomyces cerevisiae 33384 R-SCE-977324 https://reactome.org/PathwayBrowser/#/R-SCE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Saccharomyces cerevisiae 33384 R-SPO-1614614 https://reactome.org/PathwayBrowser/#/R-SPO-1614614 Cysteine is degraded to serine and H2S IEA Schizosaccharomyces pombe 33384 R-SPO-8932980 https://reactome.org/PathwayBrowser/#/R-SPO-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Schizosaccharomyces pombe 33384 R-SPO-9014766 https://reactome.org/PathwayBrowser/#/R-SPO-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Schizosaccharomyces pombe 33384 R-SPO-9034539 https://reactome.org/PathwayBrowser/#/R-SPO-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Schizosaccharomyces pombe 33384 R-SPO-977324 https://reactome.org/PathwayBrowser/#/R-SPO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Schizosaccharomyces pombe 33384 R-SSC-1483089 https://reactome.org/PathwayBrowser/#/R-SSC-1483089 PE is converted to PS by PTDSS2 IEA Sus scrofa 33384 R-SSC-1483186 https://reactome.org/PathwayBrowser/#/R-SSC-1483186 PC is converted to PS by PTDSS1 IEA Sus scrofa 33384 R-SSC-1614524 https://reactome.org/PathwayBrowser/#/R-SSC-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Sus scrofa 33384 R-SSC-1614614 https://reactome.org/PathwayBrowser/#/R-SSC-1614614 Cysteine is degraded to serine and H2S IEA Sus scrofa 33384 R-SSC-200651 https://reactome.org/PathwayBrowser/#/R-SSC-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Sus scrofa 33384 R-SSC-200735 https://reactome.org/PathwayBrowser/#/R-SSC-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Sus scrofa 33384 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 33384 R-SSC-352108 https://reactome.org/PathwayBrowser/#/R-SSC-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Sus scrofa 33384 R-SSC-352119 https://reactome.org/PathwayBrowser/#/R-SSC-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Sus scrofa 33384 R-SSC-352182 https://reactome.org/PathwayBrowser/#/R-SSC-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Sus scrofa 33384 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 33384 R-SSC-352347 https://reactome.org/PathwayBrowser/#/R-SSC-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Sus scrofa 33384 R-SSC-352354 https://reactome.org/PathwayBrowser/#/R-SSC-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Sus scrofa 33384 R-SSC-352364 https://reactome.org/PathwayBrowser/#/R-SSC-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Sus scrofa 33384 R-SSC-352371 https://reactome.org/PathwayBrowser/#/R-SSC-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Sus scrofa 33384 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 33384 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 33384 R-SSC-376200 https://reactome.org/PathwayBrowser/#/R-SSC-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Sus scrofa 33384 R-SSC-428127 https://reactome.org/PathwayBrowser/#/R-SSC-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Sus scrofa 33384 R-SSC-5694137 https://reactome.org/PathwayBrowser/#/R-SSC-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Sus scrofa 33384 R-SSC-8932980 https://reactome.org/PathwayBrowser/#/R-SSC-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Sus scrofa 33384 R-SSC-9014766 https://reactome.org/PathwayBrowser/#/R-SSC-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Sus scrofa 33384 R-SSC-9034539 https://reactome.org/PathwayBrowser/#/R-SSC-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Sus scrofa 33384 R-SSC-977324 https://reactome.org/PathwayBrowser/#/R-SSC-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Sus scrofa 33384 R-XTR-1483089 https://reactome.org/PathwayBrowser/#/R-XTR-1483089 PE is converted to PS by PTDSS2 IEA Xenopus tropicalis 33384 R-XTR-1483186 https://reactome.org/PathwayBrowser/#/R-XTR-1483186 PC is converted to PS by PTDSS1 IEA Xenopus tropicalis 33384 R-XTR-1614614 https://reactome.org/PathwayBrowser/#/R-XTR-1614614 Cysteine is degraded to serine and H2S IEA Xenopus tropicalis 33384 R-XTR-200651 https://reactome.org/PathwayBrowser/#/R-XTR-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Xenopus tropicalis 33384 R-XTR-200735 https://reactome.org/PathwayBrowser/#/R-XTR-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Xenopus tropicalis 33384 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 33384 R-XTR-352108 https://reactome.org/PathwayBrowser/#/R-XTR-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 33384 R-XTR-352119 https://reactome.org/PathwayBrowser/#/R-XTR-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 33384 R-XTR-352182 https://reactome.org/PathwayBrowser/#/R-XTR-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Xenopus tropicalis 33384 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 33384 R-XTR-352347 https://reactome.org/PathwayBrowser/#/R-XTR-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Xenopus tropicalis 33384 R-XTR-352354 https://reactome.org/PathwayBrowser/#/R-XTR-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Xenopus tropicalis 33384 R-XTR-352364 https://reactome.org/PathwayBrowser/#/R-XTR-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Xenopus tropicalis 33384 R-XTR-352371 https://reactome.org/PathwayBrowser/#/R-XTR-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Xenopus tropicalis 33384 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 33384 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 33384 R-XTR-376200 https://reactome.org/PathwayBrowser/#/R-XTR-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Xenopus tropicalis 33384 R-XTR-428127 https://reactome.org/PathwayBrowser/#/R-XTR-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Xenopus tropicalis 33384 R-XTR-5694137 https://reactome.org/PathwayBrowser/#/R-XTR-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Xenopus tropicalis 33384 R-XTR-8932980 https://reactome.org/PathwayBrowser/#/R-XTR-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Xenopus tropicalis 33384 R-XTR-9014766 https://reactome.org/PathwayBrowser/#/R-XTR-9014766 PXLP-K56-SRR dimer isomerises L-Ser to D-Ser IEA Xenopus tropicalis 33384 R-XTR-9034539 https://reactome.org/PathwayBrowser/#/R-XTR-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Xenopus tropicalis 33384 R-XTR-977324 https://reactome.org/PathwayBrowser/#/R-XTR-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Xenopus tropicalis 33409 R-BTA-5696220 https://reactome.org/PathwayBrowser/#/R-BTA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Bos taurus 33409 R-BTA-5696230 https://reactome.org/PathwayBrowser/#/R-BTA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Bos taurus 33409 R-CEL-5696230 https://reactome.org/PathwayBrowser/#/R-CEL-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Caenorhabditis elegans 33409 R-CFA-5696230 https://reactome.org/PathwayBrowser/#/R-CFA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Canis familiaris 33409 R-DME-5696230 https://reactome.org/PathwayBrowser/#/R-DME-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Drosophila melanogaster 33409 R-DRE-5696220 https://reactome.org/PathwayBrowser/#/R-DRE-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Danio rerio 33409 R-DRE-5696230 https://reactome.org/PathwayBrowser/#/R-DRE-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Danio rerio 33409 R-GGA-5696220 https://reactome.org/PathwayBrowser/#/R-GGA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Gallus gallus 33409 R-GGA-5696230 https://reactome.org/PathwayBrowser/#/R-GGA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Gallus gallus 33409 R-HSA-5696220 https://reactome.org/PathwayBrowser/#/R-HSA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) TAS Homo sapiens 33409 R-HSA-5696230 https://reactome.org/PathwayBrowser/#/R-HSA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite TAS Homo sapiens 33409 R-MMU-5696220 https://reactome.org/PathwayBrowser/#/R-MMU-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Mus musculus 33409 R-MMU-5696230 https://reactome.org/PathwayBrowser/#/R-MMU-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Mus musculus 33409 R-RNO-5696220 https://reactome.org/PathwayBrowser/#/R-RNO-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Rattus norvegicus 33409 R-RNO-5696230 https://reactome.org/PathwayBrowser/#/R-RNO-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Rattus norvegicus 33409 R-SSC-5696220 https://reactome.org/PathwayBrowser/#/R-SSC-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Sus scrofa 33409 R-SSC-5696230 https://reactome.org/PathwayBrowser/#/R-SSC-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Sus scrofa 33409 R-XTR-5696220 https://reactome.org/PathwayBrowser/#/R-XTR-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Xenopus tropicalis 33409 R-XTR-5696230 https://reactome.org/PathwayBrowser/#/R-XTR-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Xenopus tropicalis 33447 R-BTA-110375 https://reactome.org/PathwayBrowser/#/R-BTA-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break IEA Bos taurus 33447 R-BTA-5649725 https://reactome.org/PathwayBrowser/#/R-BTA-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) IEA Bos taurus 33447 R-CFA-110375 https://reactome.org/PathwayBrowser/#/R-CFA-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break IEA Canis familiaris 33447 R-CFA-5649725 https://reactome.org/PathwayBrowser/#/R-CFA-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) IEA Canis familiaris 33447 R-DDI-110375 https://reactome.org/PathwayBrowser/#/R-DDI-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break IEA Dictyostelium discoideum 33447 R-DRE-110375 https://reactome.org/PathwayBrowser/#/R-DRE-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break IEA Danio rerio 33447 R-DRE-5649725 https://reactome.org/PathwayBrowser/#/R-DRE-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) IEA Danio rerio 33447 R-HSA-110375 https://reactome.org/PathwayBrowser/#/R-HSA-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break TAS Homo sapiens 33447 R-HSA-5649725 https://reactome.org/PathwayBrowser/#/R-HSA-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) TAS Homo sapiens 33447 R-MMU-110375 https://reactome.org/PathwayBrowser/#/R-MMU-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break IEA Mus musculus 33447 R-MMU-5649725 https://reactome.org/PathwayBrowser/#/R-MMU-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) IEA Mus musculus 33447 R-RNO-110375 https://reactome.org/PathwayBrowser/#/R-RNO-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break IEA Rattus norvegicus 33447 R-RNO-5649725 https://reactome.org/PathwayBrowser/#/R-RNO-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) IEA Rattus norvegicus 33447 R-SSC-110375 https://reactome.org/PathwayBrowser/#/R-SSC-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break IEA Sus scrofa 33447 R-SSC-5649725 https://reactome.org/PathwayBrowser/#/R-SSC-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) IEA Sus scrofa 33447 R-XTR-110375 https://reactome.org/PathwayBrowser/#/R-XTR-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break IEA Xenopus tropicalis 33447 R-XTR-5649725 https://reactome.org/PathwayBrowser/#/R-XTR-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) IEA Xenopus tropicalis 3347 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(34-41) binds to AGTR1 IEA Bos taurus 3347 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGRT1 IEA Bos taurus 3347 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(34-41) binds to AGTR1 IEA Caenorhabditis elegans 3347 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGRT1 IEA Caenorhabditis elegans 3347 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(34-41) binds to AGTR1 IEA Canis familiaris 3347 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGRT1 IEA Canis familiaris 3347 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(34-41) binds to AGTR1 IEA Drosophila melanogaster 3347 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGRT1 IEA Drosophila melanogaster 3347 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(34-41) binds to AGTR1 IEA Danio rerio 3347 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGRT1 IEA Danio rerio 3347 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(34-41) binds to AGTR1 IEA Gallus gallus 3347 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGRT1 IEA Gallus gallus 3347 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(34-41) binds to AGTR1 TAS Homo sapiens 3347 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGRT1 TAS Homo sapiens 3347 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(34-41) binds to AGTR1 IEA Mus musculus 3347 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGRT1 IEA Mus musculus 3347 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(34-41) binds to AGTR1 IEA Rattus norvegicus 3347 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGRT1 IEA Rattus norvegicus 3347 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(34-41) binds to AGTR1 IEA Sus scrofa 3347 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGRT1 IEA Sus scrofa 33542 R-BTA-1655879 https://reactome.org/PathwayBrowser/#/R-BTA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Bos taurus 33542 R-BTA-9012721 https://reactome.org/PathwayBrowser/#/R-BTA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Bos taurus 33542 R-BTA-9013198 https://reactome.org/PathwayBrowser/#/R-BTA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Bos taurus 33542 R-CEL-9012721 https://reactome.org/PathwayBrowser/#/R-CEL-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Caenorhabditis elegans 33542 R-CEL-9013198 https://reactome.org/PathwayBrowser/#/R-CEL-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Caenorhabditis elegans 33542 R-CFA-1655879 https://reactome.org/PathwayBrowser/#/R-CFA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Canis familiaris 33542 R-CFA-9012721 https://reactome.org/PathwayBrowser/#/R-CFA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Canis familiaris 33542 R-CFA-9013198 https://reactome.org/PathwayBrowser/#/R-CFA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Canis familiaris 33542 R-DDI-9012721 https://reactome.org/PathwayBrowser/#/R-DDI-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Dictyostelium discoideum 33542 R-DDI-9013198 https://reactome.org/PathwayBrowser/#/R-DDI-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Dictyostelium discoideum 33542 R-DRE-9012721 https://reactome.org/PathwayBrowser/#/R-DRE-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Danio rerio 33542 R-DRE-9013198 https://reactome.org/PathwayBrowser/#/R-DRE-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Danio rerio 33542 R-GGA-9012721 https://reactome.org/PathwayBrowser/#/R-GGA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Gallus gallus 33542 R-GGA-9013198 https://reactome.org/PathwayBrowser/#/R-GGA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Gallus gallus 33542 R-HSA-1614618 https://reactome.org/PathwayBrowser/#/R-HSA-1614618 Persulfide sulfur is transferred onto sulfite IEA Homo sapiens 33542 R-HSA-1655879 https://reactome.org/PathwayBrowser/#/R-HSA-1655879 Thiosulfate can transfer its sulfur atom to glutathione TAS Homo sapiens 33542 R-HSA-9012721 https://reactome.org/PathwayBrowser/#/R-HSA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR TAS Homo sapiens 33542 R-HSA-9013198 https://reactome.org/PathwayBrowser/#/R-HSA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN TAS Homo sapiens 33542 R-MMU-1655879 https://reactome.org/PathwayBrowser/#/R-MMU-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Mus musculus 33542 R-MMU-9012721 https://reactome.org/PathwayBrowser/#/R-MMU-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Mus musculus 33542 R-MMU-9013198 https://reactome.org/PathwayBrowser/#/R-MMU-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Mus musculus 33542 R-PFA-9012721 https://reactome.org/PathwayBrowser/#/R-PFA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Plasmodium falciparum 33542 R-PFA-9013198 https://reactome.org/PathwayBrowser/#/R-PFA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Plasmodium falciparum 33542 R-RNO-1614611 https://reactome.org/PathwayBrowser/#/R-RNO-1614611 Persulfide sulfur is transferred onto sulfite TAS Rattus norvegicus 33542 R-RNO-1655879 https://reactome.org/PathwayBrowser/#/R-RNO-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Rattus norvegicus 33542 R-RNO-9012721 https://reactome.org/PathwayBrowser/#/R-RNO-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Rattus norvegicus 33542 R-RNO-9013198 https://reactome.org/PathwayBrowser/#/R-RNO-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Rattus norvegicus 33542 R-SCE-9012721 https://reactome.org/PathwayBrowser/#/R-SCE-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Saccharomyces cerevisiae 33542 R-SCE-9013198 https://reactome.org/PathwayBrowser/#/R-SCE-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Saccharomyces cerevisiae 33542 R-SPO-9012721 https://reactome.org/PathwayBrowser/#/R-SPO-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Schizosaccharomyces pombe 33542 R-SPO-9013198 https://reactome.org/PathwayBrowser/#/R-SPO-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Schizosaccharomyces pombe 33542 R-SSC-1655879 https://reactome.org/PathwayBrowser/#/R-SSC-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Sus scrofa 33542 R-SSC-9012721 https://reactome.org/PathwayBrowser/#/R-SSC-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Sus scrofa 33542 R-SSC-9013198 https://reactome.org/PathwayBrowser/#/R-SSC-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Sus scrofa 33542 R-XTR-1655879 https://reactome.org/PathwayBrowser/#/R-XTR-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Xenopus tropicalis 33542 R-XTR-9012721 https://reactome.org/PathwayBrowser/#/R-XTR-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Xenopus tropicalis 33542 R-XTR-9013198 https://reactome.org/PathwayBrowser/#/R-XTR-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Xenopus tropicalis 33575 R-BTA-6789310 https://reactome.org/PathwayBrowser/#/R-BTA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Bos taurus 33575 R-CFA-6789310 https://reactome.org/PathwayBrowser/#/R-CFA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Canis familiaris 33575 R-DDI-6789310 https://reactome.org/PathwayBrowser/#/R-DDI-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Dictyostelium discoideum 33575 R-DRE-6789310 https://reactome.org/PathwayBrowser/#/R-DRE-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Danio rerio 33575 R-GGA-6789310 https://reactome.org/PathwayBrowser/#/R-GGA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Gallus gallus 33575 R-HSA-6789310 https://reactome.org/PathwayBrowser/#/R-HSA-6789310 LIPs hydrolyse TG to DAG and RCOOH TAS Homo sapiens 33575 R-MMU-6789310 https://reactome.org/PathwayBrowser/#/R-MMU-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Mus musculus 33575 R-PFA-6789310 https://reactome.org/PathwayBrowser/#/R-PFA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Plasmodium falciparum 33575 R-RNO-6789310 https://reactome.org/PathwayBrowser/#/R-RNO-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Rattus norvegicus 33575 R-SCE-6789310 https://reactome.org/PathwayBrowser/#/R-SCE-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Saccharomyces cerevisiae 33575 R-SPO-6789310 https://reactome.org/PathwayBrowser/#/R-SPO-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Schizosaccharomyces pombe 33575 R-SSC-6789310 https://reactome.org/PathwayBrowser/#/R-SSC-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Sus scrofa 33697 R-BTA-112381 https://reactome.org/PathwayBrowser/#/R-BTA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Bos taurus 33697 R-BTA-112383 https://reactome.org/PathwayBrowser/#/R-BTA-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Bos taurus 33697 R-BTA-112385 https://reactome.org/PathwayBrowser/#/R-BTA-112385 Addition of nucleotides leads to transcript elongation IEA Bos taurus 33697 R-BTA-112392 https://reactome.org/PathwayBrowser/#/R-BTA-112392 Resumption of elongation after recovery from pausing IEA Bos taurus 33697 R-BTA-112395 https://reactome.org/PathwayBrowser/#/R-BTA-112395 Abortive termination of elongation after arrest IEA Bos taurus 33697 R-BTA-112396 https://reactome.org/PathwayBrowser/#/R-BTA-112396 Separation of elongating transcript from template IEA Bos taurus 33697 R-BTA-113402 https://reactome.org/PathwayBrowser/#/R-BTA-113402 Formation of DSIF:NELF:early elongation complex IEA Bos taurus 33697 R-BTA-113407 https://reactome.org/PathwayBrowser/#/R-BTA-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Bos taurus 33697 R-BTA-113409 https://reactome.org/PathwayBrowser/#/R-BTA-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Bos taurus 33697 R-BTA-113411 https://reactome.org/PathwayBrowser/#/R-BTA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Bos taurus 33697 R-BTA-113412 https://reactome.org/PathwayBrowser/#/R-BTA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Bos taurus 33697 R-BTA-113413 https://reactome.org/PathwayBrowser/#/R-BTA-113413 TFIIS-mediated recovery of elongation from arrest IEA Bos taurus 33697 R-BTA-113414 https://reactome.org/PathwayBrowser/#/R-BTA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Bos taurus 33697 R-BTA-113504 https://reactome.org/PathwayBrowser/#/R-BTA-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Bos taurus 33697 R-BTA-158441 https://reactome.org/PathwayBrowser/#/R-BTA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Bos taurus 33697 R-BTA-158447 https://reactome.org/PathwayBrowser/#/R-BTA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Bos taurus 33697 R-BTA-158481 https://reactome.org/PathwayBrowser/#/R-BTA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Bos taurus 33697 R-BTA-158484 https://reactome.org/PathwayBrowser/#/R-BTA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Bos taurus 33697 R-BTA-159046 https://reactome.org/PathwayBrowser/#/R-BTA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Bos taurus 33697 R-BTA-159050 https://reactome.org/PathwayBrowser/#/R-BTA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Bos taurus 33697 R-BTA-159101 https://reactome.org/PathwayBrowser/#/R-BTA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Bos taurus 33697 R-BTA-174425 https://reactome.org/PathwayBrowser/#/R-BTA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Bos taurus 33697 R-BTA-174427 https://reactome.org/PathwayBrowser/#/R-BTA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Bos taurus 33697 R-BTA-174438 https://reactome.org/PathwayBrowser/#/R-BTA-174438 Formation of the Flap Intermediate on the C-strand IEA Bos taurus 33697 R-BTA-174439 https://reactome.org/PathwayBrowser/#/R-BTA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Bos taurus 33697 R-BTA-174444 https://reactome.org/PathwayBrowser/#/R-BTA-174444 Formation of C-strand Okazaki fragments IEA Bos taurus 33697 R-BTA-174447 https://reactome.org/PathwayBrowser/#/R-BTA-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Bos taurus 33697 R-BTA-174448 https://reactome.org/PathwayBrowser/#/R-BTA-174448 Formation of Processive Complex on the C-strand of the telomere IEA Bos taurus 33697 R-BTA-174452 https://reactome.org/PathwayBrowser/#/R-BTA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Bos taurus 33697 R-BTA-2106615 https://reactome.org/PathwayBrowser/#/R-BTA-2106615 Removal of siRNA passenger strand IEA Bos taurus 33697 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 33697 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 33697 R-BTA-426489 https://reactome.org/PathwayBrowser/#/R-BTA-426489 RISC binds inexactly matching target RNAs IEA Bos taurus 33697 R-BTA-426520 https://reactome.org/PathwayBrowser/#/R-BTA-426520 Endonucleolytic RISC hydrolyzes target RNAs IEA Bos taurus 33697 R-BTA-426522 https://reactome.org/PathwayBrowser/#/R-BTA-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Bos taurus 33697 R-BTA-429961 https://reactome.org/PathwayBrowser/#/R-BTA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Bos taurus 33697 R-BTA-450387 https://reactome.org/PathwayBrowser/#/R-BTA-450387 HuR binds the CRM1 nuclear export machinery IEA Bos taurus 33697 R-BTA-450394 https://reactome.org/PathwayBrowser/#/R-BTA-450394 p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta IEA Bos taurus 33697 R-BTA-450400 https://reactome.org/PathwayBrowser/#/R-BTA-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Bos taurus 33697 R-BTA-450406 https://reactome.org/PathwayBrowser/#/R-BTA-450406 p-S92,203-BRF1 binds 14-3-3 IEA Bos taurus 33697 R-BTA-450422 https://reactome.org/PathwayBrowser/#/R-BTA-450422 KSRP recruits RNA degradation activities IEA Bos taurus 33697 R-BTA-450431 https://reactome.org/PathwayBrowser/#/R-BTA-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Bos taurus 33697 R-BTA-450434 https://reactome.org/PathwayBrowser/#/R-BTA-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA IEA Bos taurus 33697 R-BTA-450463 https://reactome.org/PathwayBrowser/#/R-BTA-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Bos taurus 33697 R-BTA-450466 https://reactome.org/PathwayBrowser/#/R-BTA-450466 AUF1:mRNA complex is destroyed IEA Bos taurus 33697 R-BTA-450474 https://reactome.org/PathwayBrowser/#/R-BTA-450474 MK2 phosphorylates BRF1 IEA Bos taurus 33697 R-BTA-450488 https://reactome.org/PathwayBrowser/#/R-BTA-450488 BRF1 Complex recruits RNA degradation activities IEA Bos taurus 33697 R-BTA-450494 https://reactome.org/PathwayBrowser/#/R-BTA-450494 HuR binds mRNAs in the nucleus IEA Bos taurus 33697 R-BTA-450517 https://reactome.org/PathwayBrowser/#/R-BTA-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Bos taurus 33697 R-BTA-450551 https://reactome.org/PathwayBrowser/#/R-BTA-450551 AUF1 binds translation and heat shock proteins IEA Bos taurus 33697 R-BTA-450580 https://reactome.org/PathwayBrowser/#/R-BTA-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Bos taurus 33697 R-BTA-450592 https://reactome.org/PathwayBrowser/#/R-BTA-450592 KSRP binds AU-rich element in 3' UTR of mRNA IEA Bos taurus 33697 R-BTA-450595 https://reactome.org/PathwayBrowser/#/R-BTA-450595 HuR:mRNA complex translocates from the nucleus to the cytosol IEA Bos taurus 33697 R-BTA-482788 https://reactome.org/PathwayBrowser/#/R-BTA-482788 p-S54,92,203-BRF1 binds 14-3-3 IEA Bos taurus 33697 R-BTA-517674 https://reactome.org/PathwayBrowser/#/R-BTA-517674 p-S158,221-HuR binds mRNA IEA Bos taurus 33697 R-BTA-517705 https://reactome.org/PathwayBrowser/#/R-BTA-517705 p-S318,221-HuR binds mRNA IEA Bos taurus 33697 R-BTA-68913 https://reactome.org/PathwayBrowser/#/R-BTA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Bos taurus 33697 R-BTA-68950 https://reactome.org/PathwayBrowser/#/R-BTA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Bos taurus 33697 R-BTA-69053 https://reactome.org/PathwayBrowser/#/R-BTA-69053 RFC binding displaces Pol Alpha IEA Bos taurus 33697 R-BTA-69063 https://reactome.org/PathwayBrowser/#/R-BTA-69063 Loading of PCNA - Sliding Clamp Formation IEA Bos taurus 33697 R-BTA-69068 https://reactome.org/PathwayBrowser/#/R-BTA-69068 RFC dissociates after sliding clamp formation IEA Bos taurus 33697 R-BTA-69074 https://reactome.org/PathwayBrowser/#/R-BTA-69074 Formation of Processive Complex IEA Bos taurus 33697 R-BTA-69116 https://reactome.org/PathwayBrowser/#/R-BTA-69116 Formation of Okazaki fragments IEA Bos taurus 33697 R-BTA-69127 https://reactome.org/PathwayBrowser/#/R-BTA-69127 Formation of the Flap Intermediate IEA Bos taurus 33697 R-BTA-69140 https://reactome.org/PathwayBrowser/#/R-BTA-69140 RPA binds to the Flap IEA Bos taurus 33697 R-BTA-69142 https://reactome.org/PathwayBrowser/#/R-BTA-69142 Recruitment of Dna2 endonuclease IEA Bos taurus 33697 R-BTA-69144 https://reactome.org/PathwayBrowser/#/R-BTA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Bos taurus 33697 R-BTA-69152 https://reactome.org/PathwayBrowser/#/R-BTA-69152 Removal of remaining Flap IEA Bos taurus 33697 R-BTA-72095 https://reactome.org/PathwayBrowser/#/R-BTA-72095 Internal Methylation of mRNA IEA Bos taurus 33697 R-BTA-72180 https://reactome.org/PathwayBrowser/#/R-BTA-72180 Cleavage of mRNA at the 3'-end IEA Bos taurus 33697 R-BTA-72185 https://reactome.org/PathwayBrowser/#/R-BTA-72185 mRNA polyadenylation IEA Bos taurus 33697 R-BTA-74986 https://reactome.org/PathwayBrowser/#/R-BTA-74986 Elongation of pre-rRNA transcript IEA Bos taurus 33697 R-BTA-75083 https://reactome.org/PathwayBrowser/#/R-BTA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Bos taurus 33697 R-BTA-75097 https://reactome.org/PathwayBrowser/#/R-BTA-75097 Transport of the export-competent mRNP complex through the NPC IEA Bos taurus 33697 R-BTA-77077 https://reactome.org/PathwayBrowser/#/R-BTA-77077 Capping complex formation IEA Bos taurus 33697 R-BTA-77078 https://reactome.org/PathwayBrowser/#/R-BTA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Bos taurus 33697 R-BTA-77081 https://reactome.org/PathwayBrowser/#/R-BTA-77081 Formation of the CE:GMP intermediate complex IEA Bos taurus 33697 R-BTA-77083 https://reactome.org/PathwayBrowser/#/R-BTA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Bos taurus 33697 R-BTA-77085 https://reactome.org/PathwayBrowser/#/R-BTA-77085 Dissociation of transcript with 5'-GMP from GT IEA Bos taurus 33697 R-BTA-77090 https://reactome.org/PathwayBrowser/#/R-BTA-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Bos taurus 33697 R-BTA-77095 https://reactome.org/PathwayBrowser/#/R-BTA-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Bos taurus 33697 R-BTA-77589 https://reactome.org/PathwayBrowser/#/R-BTA-77589 Recognition of AAUAAA sequence by CPSF IEA Bos taurus 33697 R-BTA-77590 https://reactome.org/PathwayBrowser/#/R-BTA-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Bos taurus 33697 R-BTA-77591 https://reactome.org/PathwayBrowser/#/R-BTA-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Bos taurus 33697 R-BTA-77592 https://reactome.org/PathwayBrowser/#/R-BTA-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Bos taurus 33697 R-BTA-77593 https://reactome.org/PathwayBrowser/#/R-BTA-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Bos taurus 33697 R-BTA-77594 https://reactome.org/PathwayBrowser/#/R-BTA-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Bos taurus 33697 R-BTA-77608 https://reactome.org/PathwayBrowser/#/R-BTA-77608 Binding of A1CF to stem-looped RNA IEA Bos taurus 33697 R-BTA-77609 https://reactome.org/PathwayBrowser/#/R-BTA-77609 Binding of APOBEC-1 to form editosome IEA Bos taurus 33697 R-BTA-77614 https://reactome.org/PathwayBrowser/#/R-BTA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Bos taurus 33697 R-BTA-77615 https://reactome.org/PathwayBrowser/#/R-BTA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Bos taurus 33697 R-BTA-83677 https://reactome.org/PathwayBrowser/#/R-BTA-83677 C4 deamination of cytidine IEA Bos taurus 33697 R-BTA-9009936 https://reactome.org/PathwayBrowser/#/R-BTA-9009936 RNASEL cleaves cellular ssRNA IEA Bos taurus 33697 R-BTA-9023909 https://reactome.org/PathwayBrowser/#/R-BTA-9023909 C3PO hydrolyzes cleaved passenger strand IEA Bos taurus 33697 R-BTA-927789 https://reactome.org/PathwayBrowser/#/R-BTA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Bos taurus 33697 R-BTA-927813 https://reactome.org/PathwayBrowser/#/R-BTA-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Bos taurus 33697 R-BTA-927830 https://reactome.org/PathwayBrowser/#/R-BTA-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex IEA Bos taurus 33697 R-BTA-927832 https://reactome.org/PathwayBrowser/#/R-BTA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Bos taurus 33697 R-BTA-927836 https://reactome.org/PathwayBrowser/#/R-BTA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Bos taurus 33697 R-BTA-927889 https://reactome.org/PathwayBrowser/#/R-BTA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Bos taurus 33697 R-BTA-9833777 https://reactome.org/PathwayBrowser/#/R-BTA-9833777 PKR binds activating host RNA IEA Bos taurus 33697 R-CEL-112383 https://reactome.org/PathwayBrowser/#/R-CEL-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Caenorhabditis elegans 33697 R-CEL-112385 https://reactome.org/PathwayBrowser/#/R-CEL-112385 Addition of nucleotides leads to transcript elongation IEA Caenorhabditis elegans 33697 R-CEL-112392 https://reactome.org/PathwayBrowser/#/R-CEL-112392 Resumption of elongation after recovery from pausing IEA Caenorhabditis elegans 33697 R-CEL-112395 https://reactome.org/PathwayBrowser/#/R-CEL-112395 Abortive termination of elongation after arrest IEA Caenorhabditis elegans 33697 R-CEL-112396 https://reactome.org/PathwayBrowser/#/R-CEL-112396 Separation of elongating transcript from template IEA Caenorhabditis elegans 33697 R-CEL-113407 https://reactome.org/PathwayBrowser/#/R-CEL-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Caenorhabditis elegans 33697 R-CEL-113409 https://reactome.org/PathwayBrowser/#/R-CEL-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Caenorhabditis elegans 33697 R-CEL-113411 https://reactome.org/PathwayBrowser/#/R-CEL-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Caenorhabditis elegans 33697 R-CEL-113412 https://reactome.org/PathwayBrowser/#/R-CEL-113412 Pol II elongation complex moves on the template as transcript elongates IEA Caenorhabditis elegans 33697 R-CEL-113413 https://reactome.org/PathwayBrowser/#/R-CEL-113413 TFIIS-mediated recovery of elongation from arrest IEA Caenorhabditis elegans 33697 R-CEL-113414 https://reactome.org/PathwayBrowser/#/R-CEL-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Caenorhabditis elegans 33697 R-CEL-113504 https://reactome.org/PathwayBrowser/#/R-CEL-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Caenorhabditis elegans 33697 R-CEL-159101 https://reactome.org/PathwayBrowser/#/R-CEL-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Caenorhabditis elegans 33697 R-CEL-2106615 https://reactome.org/PathwayBrowser/#/R-CEL-2106615 Removal of siRNA passenger strand IEA Caenorhabditis elegans 33697 R-CEL-426520 https://reactome.org/PathwayBrowser/#/R-CEL-426520 Endonucleolytic RISC hydrolyzes target RNAs IEA Caenorhabditis elegans 33697 R-CEL-429961 https://reactome.org/PathwayBrowser/#/R-CEL-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Caenorhabditis elegans 33697 R-CEL-450394 https://reactome.org/PathwayBrowser/#/R-CEL-450394 p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta IEA Caenorhabditis elegans 33697 R-CEL-450400 https://reactome.org/PathwayBrowser/#/R-CEL-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Caenorhabditis elegans 33697 R-CEL-450406 https://reactome.org/PathwayBrowser/#/R-CEL-450406 p-S92,203-BRF1 binds 14-3-3 IEA Caenorhabditis elegans 33697 R-CEL-450431 https://reactome.org/PathwayBrowser/#/R-CEL-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Caenorhabditis elegans 33697 R-CEL-450463 https://reactome.org/PathwayBrowser/#/R-CEL-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Caenorhabditis elegans 33697 R-CEL-450474 https://reactome.org/PathwayBrowser/#/R-CEL-450474 MK2 phosphorylates BRF1 IEA Caenorhabditis elegans 33697 R-CEL-450488 https://reactome.org/PathwayBrowser/#/R-CEL-450488 BRF1 Complex recruits RNA degradation activities IEA Caenorhabditis elegans 33697 R-CEL-450490 https://reactome.org/PathwayBrowser/#/R-CEL-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Caenorhabditis elegans 33697 R-CEL-450517 https://reactome.org/PathwayBrowser/#/R-CEL-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Caenorhabditis elegans 33697 R-CEL-450592 https://reactome.org/PathwayBrowser/#/R-CEL-450592 KSRP binds AU-rich element in 3' UTR of mRNA IEA Caenorhabditis elegans 33697 R-CEL-482788 https://reactome.org/PathwayBrowser/#/R-CEL-482788 p-S54,92,203-BRF1 binds 14-3-3 IEA Caenorhabditis elegans 33697 R-CEL-68913 https://reactome.org/PathwayBrowser/#/R-CEL-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Caenorhabditis elegans 33697 R-CEL-68950 https://reactome.org/PathwayBrowser/#/R-CEL-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Caenorhabditis elegans 33697 R-CEL-69053 https://reactome.org/PathwayBrowser/#/R-CEL-69053 RFC binding displaces Pol Alpha IEA Caenorhabditis elegans 33697 R-CEL-69063 https://reactome.org/PathwayBrowser/#/R-CEL-69063 Loading of PCNA - Sliding Clamp Formation IEA Caenorhabditis elegans 33697 R-CEL-69068 https://reactome.org/PathwayBrowser/#/R-CEL-69068 RFC dissociates after sliding clamp formation IEA Caenorhabditis elegans 33697 R-CEL-69074 https://reactome.org/PathwayBrowser/#/R-CEL-69074 Formation of Processive Complex IEA Caenorhabditis elegans 33697 R-CEL-69116 https://reactome.org/PathwayBrowser/#/R-CEL-69116 Formation of Okazaki fragments IEA Caenorhabditis elegans 33697 R-CEL-69127 https://reactome.org/PathwayBrowser/#/R-CEL-69127 Formation of the Flap Intermediate IEA Caenorhabditis elegans 33697 R-CEL-69142 https://reactome.org/PathwayBrowser/#/R-CEL-69142 Recruitment of Dna2 endonuclease IEA Caenorhabditis elegans 33697 R-CEL-69152 https://reactome.org/PathwayBrowser/#/R-CEL-69152 Removal of remaining Flap IEA Caenorhabditis elegans 33697 R-CEL-72180 https://reactome.org/PathwayBrowser/#/R-CEL-72180 Cleavage of mRNA at the 3'-end IEA Caenorhabditis elegans 33697 R-CEL-72185 https://reactome.org/PathwayBrowser/#/R-CEL-72185 mRNA polyadenylation IEA Caenorhabditis elegans 33697 R-CEL-74986 https://reactome.org/PathwayBrowser/#/R-CEL-74986 Elongation of pre-rRNA transcript IEA Caenorhabditis elegans 33697 R-CEL-77077 https://reactome.org/PathwayBrowser/#/R-CEL-77077 Capping complex formation IEA Caenorhabditis elegans 33697 R-CEL-77078 https://reactome.org/PathwayBrowser/#/R-CEL-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Caenorhabditis elegans 33697 R-CEL-77081 https://reactome.org/PathwayBrowser/#/R-CEL-77081 Formation of the CE:GMP intermediate complex IEA Caenorhabditis elegans 33697 R-CEL-77083 https://reactome.org/PathwayBrowser/#/R-CEL-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Caenorhabditis elegans 33697 R-CEL-77085 https://reactome.org/PathwayBrowser/#/R-CEL-77085 Dissociation of transcript with 5'-GMP from GT IEA Caenorhabditis elegans 33697 R-CEL-77090 https://reactome.org/PathwayBrowser/#/R-CEL-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Caenorhabditis elegans 33697 R-CEL-77095 https://reactome.org/PathwayBrowser/#/R-CEL-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Caenorhabditis elegans 33697 R-CEL-77589 https://reactome.org/PathwayBrowser/#/R-CEL-77589 Recognition of AAUAAA sequence by CPSF IEA Caenorhabditis elegans 33697 R-CEL-77590 https://reactome.org/PathwayBrowser/#/R-CEL-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Caenorhabditis elegans 33697 R-CEL-77591 https://reactome.org/PathwayBrowser/#/R-CEL-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Caenorhabditis elegans 33697 R-CEL-77592 https://reactome.org/PathwayBrowser/#/R-CEL-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Caenorhabditis elegans 33697 R-CEL-77593 https://reactome.org/PathwayBrowser/#/R-CEL-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Caenorhabditis elegans 33697 R-CEL-77615 https://reactome.org/PathwayBrowser/#/R-CEL-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Caenorhabditis elegans 33697 R-CEL-927789 https://reactome.org/PathwayBrowser/#/R-CEL-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Caenorhabditis elegans 33697 R-CEL-927832 https://reactome.org/PathwayBrowser/#/R-CEL-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Caenorhabditis elegans 33697 R-CEL-927836 https://reactome.org/PathwayBrowser/#/R-CEL-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Caenorhabditis elegans 33697 R-CEL-927889 https://reactome.org/PathwayBrowser/#/R-CEL-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Caenorhabditis elegans 33697 R-CEL-9833777 https://reactome.org/PathwayBrowser/#/R-CEL-9833777 PKR binds activating host RNA IEA Caenorhabditis elegans 33697 R-CFA-112381 https://reactome.org/PathwayBrowser/#/R-CFA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Canis familiaris 33697 R-CFA-112383 https://reactome.org/PathwayBrowser/#/R-CFA-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Canis familiaris 33697 R-CFA-112385 https://reactome.org/PathwayBrowser/#/R-CFA-112385 Addition of nucleotides leads to transcript elongation IEA Canis familiaris 33697 R-CFA-112392 https://reactome.org/PathwayBrowser/#/R-CFA-112392 Resumption of elongation after recovery from pausing IEA Canis familiaris 33697 R-CFA-112395 https://reactome.org/PathwayBrowser/#/R-CFA-112395 Abortive termination of elongation after arrest IEA Canis familiaris 33697 R-CFA-112396 https://reactome.org/PathwayBrowser/#/R-CFA-112396 Separation of elongating transcript from template IEA Canis familiaris 33697 R-CFA-113402 https://reactome.org/PathwayBrowser/#/R-CFA-113402 Formation of DSIF:NELF:early elongation complex IEA Canis familiaris 33697 R-CFA-113407 https://reactome.org/PathwayBrowser/#/R-CFA-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Canis familiaris 33697 R-CFA-113409 https://reactome.org/PathwayBrowser/#/R-CFA-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Canis familiaris 33697 R-CFA-113411 https://reactome.org/PathwayBrowser/#/R-CFA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Canis familiaris 33697 R-CFA-113412 https://reactome.org/PathwayBrowser/#/R-CFA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Canis familiaris 33697 R-CFA-113413 https://reactome.org/PathwayBrowser/#/R-CFA-113413 TFIIS-mediated recovery of elongation from arrest IEA Canis familiaris 33697 R-CFA-113414 https://reactome.org/PathwayBrowser/#/R-CFA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Canis familiaris 33697 R-CFA-113429 https://reactome.org/PathwayBrowser/#/R-CFA-113429 Elongating transcript encounters a lesion in the template IEA Canis familiaris 33697 R-CFA-113504 https://reactome.org/PathwayBrowser/#/R-CFA-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Canis familiaris 33697 R-CFA-158441 https://reactome.org/PathwayBrowser/#/R-CFA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Canis familiaris 33697 R-CFA-158447 https://reactome.org/PathwayBrowser/#/R-CFA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Canis familiaris 33697 R-CFA-158481 https://reactome.org/PathwayBrowser/#/R-CFA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Canis familiaris 33697 R-CFA-158484 https://reactome.org/PathwayBrowser/#/R-CFA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Canis familiaris 33697 R-CFA-159046 https://reactome.org/PathwayBrowser/#/R-CFA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Canis familiaris 33697 R-CFA-159050 https://reactome.org/PathwayBrowser/#/R-CFA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Canis familiaris 33697 R-CFA-174425 https://reactome.org/PathwayBrowser/#/R-CFA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Canis familiaris 33697 R-CFA-174427 https://reactome.org/PathwayBrowser/#/R-CFA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Canis familiaris 33697 R-CFA-174438 https://reactome.org/PathwayBrowser/#/R-CFA-174438 Formation of the Flap Intermediate on the C-strand IEA Canis familiaris 33697 R-CFA-174439 https://reactome.org/PathwayBrowser/#/R-CFA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Canis familiaris 33697 R-CFA-174444 https://reactome.org/PathwayBrowser/#/R-CFA-174444 Formation of C-strand Okazaki fragments IEA Canis familiaris 33697 R-CFA-174447 https://reactome.org/PathwayBrowser/#/R-CFA-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Canis familiaris 33697 R-CFA-174448 https://reactome.org/PathwayBrowser/#/R-CFA-174448 Formation of Processive Complex on the C-strand of the telomere IEA Canis familiaris 33697 R-CFA-174452 https://reactome.org/PathwayBrowser/#/R-CFA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Canis familiaris 33697 R-CFA-2106615 https://reactome.org/PathwayBrowser/#/R-CFA-2106615 Removal of siRNA passenger strand IEA Canis familiaris 33697 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 33697 R-CFA-426489 https://reactome.org/PathwayBrowser/#/R-CFA-426489 RISC binds inexactly matching target RNAs IEA Canis familiaris 33697 R-CFA-426520 https://reactome.org/PathwayBrowser/#/R-CFA-426520 Endonucleolytic RISC hydrolyzes target RNAs IEA Canis familiaris 33697 R-CFA-426522 https://reactome.org/PathwayBrowser/#/R-CFA-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Canis familiaris 33697 R-CFA-429961 https://reactome.org/PathwayBrowser/#/R-CFA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Canis familiaris 33697 R-CFA-450387 https://reactome.org/PathwayBrowser/#/R-CFA-450387 HuR binds the CRM1 nuclear export machinery IEA Canis familiaris 33697 R-CFA-450400 https://reactome.org/PathwayBrowser/#/R-CFA-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Canis familiaris 33697 R-CFA-450422 https://reactome.org/PathwayBrowser/#/R-CFA-450422 KSRP recruits RNA degradation activities IEA Canis familiaris 33697 R-CFA-450431 https://reactome.org/PathwayBrowser/#/R-CFA-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Canis familiaris 33697 R-CFA-450434 https://reactome.org/PathwayBrowser/#/R-CFA-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA IEA Canis familiaris 33697 R-CFA-450466 https://reactome.org/PathwayBrowser/#/R-CFA-450466 AUF1:mRNA complex is destroyed IEA Canis familiaris 33697 R-CFA-450488 https://reactome.org/PathwayBrowser/#/R-CFA-450488 BRF1 Complex recruits RNA degradation activities IEA Canis familiaris 33697 R-CFA-450494 https://reactome.org/PathwayBrowser/#/R-CFA-450494 HuR binds mRNAs in the nucleus IEA Canis familiaris 33697 R-CFA-450517 https://reactome.org/PathwayBrowser/#/R-CFA-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Canis familiaris 33697 R-CFA-450551 https://reactome.org/PathwayBrowser/#/R-CFA-450551 AUF1 binds translation and heat shock proteins IEA Canis familiaris 33697 R-CFA-450580 https://reactome.org/PathwayBrowser/#/R-CFA-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Canis familiaris 33697 R-CFA-450592 https://reactome.org/PathwayBrowser/#/R-CFA-450592 KSRP binds AU-rich element in 3' UTR of mRNA IEA Canis familiaris 33697 R-CFA-450595 https://reactome.org/PathwayBrowser/#/R-CFA-450595 HuR:mRNA complex translocates from the nucleus to the cytosol IEA Canis familiaris 33697 R-CFA-517674 https://reactome.org/PathwayBrowser/#/R-CFA-517674 p-S158,221-HuR binds mRNA IEA Canis familiaris 33697 R-CFA-517705 https://reactome.org/PathwayBrowser/#/R-CFA-517705 p-S318,221-HuR binds mRNA IEA Canis familiaris 33697 R-CFA-68913 https://reactome.org/PathwayBrowser/#/R-CFA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Canis familiaris 33697 R-CFA-68950 https://reactome.org/PathwayBrowser/#/R-CFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Canis familiaris 33697 R-CFA-69053 https://reactome.org/PathwayBrowser/#/R-CFA-69053 RFC binding displaces Pol Alpha IEA Canis familiaris 33697 R-CFA-69063 https://reactome.org/PathwayBrowser/#/R-CFA-69063 Loading of PCNA - Sliding Clamp Formation IEA Canis familiaris 33697 R-CFA-69068 https://reactome.org/PathwayBrowser/#/R-CFA-69068 RFC dissociates after sliding clamp formation IEA Canis familiaris 33697 R-CFA-69074 https://reactome.org/PathwayBrowser/#/R-CFA-69074 Formation of Processive Complex IEA Canis familiaris 33697 R-CFA-69116 https://reactome.org/PathwayBrowser/#/R-CFA-69116 Formation of Okazaki fragments IEA Canis familiaris 33697 R-CFA-69127 https://reactome.org/PathwayBrowser/#/R-CFA-69127 Formation of the Flap Intermediate IEA Canis familiaris 33697 R-CFA-69140 https://reactome.org/PathwayBrowser/#/R-CFA-69140 RPA binds to the Flap IEA Canis familiaris 33697 R-CFA-69142 https://reactome.org/PathwayBrowser/#/R-CFA-69142 Recruitment of Dna2 endonuclease IEA Canis familiaris 33697 R-CFA-69144 https://reactome.org/PathwayBrowser/#/R-CFA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Canis familiaris 33697 R-CFA-69152 https://reactome.org/PathwayBrowser/#/R-CFA-69152 Removal of remaining Flap IEA Canis familiaris 33697 R-CFA-72095 https://reactome.org/PathwayBrowser/#/R-CFA-72095 Internal Methylation of mRNA IEA Canis familiaris 33697 R-CFA-72180 https://reactome.org/PathwayBrowser/#/R-CFA-72180 Cleavage of mRNA at the 3'-end IEA Canis familiaris 33697 R-CFA-74986 https://reactome.org/PathwayBrowser/#/R-CFA-74986 Elongation of pre-rRNA transcript IEA Canis familiaris 33697 R-CFA-75083 https://reactome.org/PathwayBrowser/#/R-CFA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Canis familiaris 33697 R-CFA-75097 https://reactome.org/PathwayBrowser/#/R-CFA-75097 Transport of the export-competent mRNP complex through the NPC IEA Canis familiaris 33697 R-CFA-77077 https://reactome.org/PathwayBrowser/#/R-CFA-77077 Capping complex formation IEA Canis familiaris 33697 R-CFA-77078 https://reactome.org/PathwayBrowser/#/R-CFA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Canis familiaris 33697 R-CFA-77081 https://reactome.org/PathwayBrowser/#/R-CFA-77081 Formation of the CE:GMP intermediate complex IEA Canis familiaris 33697 R-CFA-77083 https://reactome.org/PathwayBrowser/#/R-CFA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Canis familiaris 33697 R-CFA-77085 https://reactome.org/PathwayBrowser/#/R-CFA-77085 Dissociation of transcript with 5'-GMP from GT IEA Canis familiaris 33697 R-CFA-77090 https://reactome.org/PathwayBrowser/#/R-CFA-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Canis familiaris 33697 R-CFA-77095 https://reactome.org/PathwayBrowser/#/R-CFA-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Canis familiaris 33697 R-CFA-77589 https://reactome.org/PathwayBrowser/#/R-CFA-77589 Recognition of AAUAAA sequence by CPSF IEA Canis familiaris 33697 R-CFA-77590 https://reactome.org/PathwayBrowser/#/R-CFA-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Canis familiaris 33697 R-CFA-77592 https://reactome.org/PathwayBrowser/#/R-CFA-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Canis familiaris 33697 R-CFA-77594 https://reactome.org/PathwayBrowser/#/R-CFA-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Canis familiaris 33697 R-CFA-77608 https://reactome.org/PathwayBrowser/#/R-CFA-77608 Binding of A1CF to stem-looped RNA IEA Canis familiaris 33697 R-CFA-77609 https://reactome.org/PathwayBrowser/#/R-CFA-77609 Binding of APOBEC-1 to form editosome IEA Canis familiaris 33697 R-CFA-77614 https://reactome.org/PathwayBrowser/#/R-CFA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Canis familiaris 33697 R-CFA-77615 https://reactome.org/PathwayBrowser/#/R-CFA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Canis familiaris 33697 R-CFA-83677 https://reactome.org/PathwayBrowser/#/R-CFA-83677 C4 deamination of cytidine IEA Canis familiaris 33697 R-CFA-8849157 https://reactome.org/PathwayBrowser/#/R-CFA-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Canis familiaris 33697 R-CFA-9009936 https://reactome.org/PathwayBrowser/#/R-CFA-9009936 RNASEL cleaves cellular ssRNA IEA Canis familiaris 33697 R-CFA-927789 https://reactome.org/PathwayBrowser/#/R-CFA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Canis familiaris 33697 R-CFA-927813 https://reactome.org/PathwayBrowser/#/R-CFA-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Canis familiaris 33697 R-CFA-927830 https://reactome.org/PathwayBrowser/#/R-CFA-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex IEA Canis familiaris 33697 R-CFA-927832 https://reactome.org/PathwayBrowser/#/R-CFA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Canis familiaris 33697 R-CFA-927836 https://reactome.org/PathwayBrowser/#/R-CFA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Canis familiaris 33697 R-CFA-927889 https://reactome.org/PathwayBrowser/#/R-CFA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Canis familiaris 33697 R-CFA-9833777 https://reactome.org/PathwayBrowser/#/R-CFA-9833777 PKR binds activating host RNA IEA Canis familiaris 33697 R-DDI-112383 https://reactome.org/PathwayBrowser/#/R-DDI-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Dictyostelium discoideum 33697 R-DDI-113407 https://reactome.org/PathwayBrowser/#/R-DDI-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Dictyostelium discoideum 33697 R-DDI-113409 https://reactome.org/PathwayBrowser/#/R-DDI-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Dictyostelium discoideum 33697 R-DDI-113504 https://reactome.org/PathwayBrowser/#/R-DDI-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Dictyostelium discoideum 33697 R-DDI-450400 https://reactome.org/PathwayBrowser/#/R-DDI-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Dictyostelium discoideum 33697 R-DDI-450431 https://reactome.org/PathwayBrowser/#/R-DDI-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Dictyostelium discoideum 33697 R-DDI-450434 https://reactome.org/PathwayBrowser/#/R-DDI-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA IEA Dictyostelium discoideum 33697 R-DDI-450466 https://reactome.org/PathwayBrowser/#/R-DDI-450466 AUF1:mRNA complex is destroyed IEA Dictyostelium discoideum 33697 R-DDI-450488 https://reactome.org/PathwayBrowser/#/R-DDI-450488 BRF1 Complex recruits RNA degradation activities IEA Dictyostelium discoideum 33697 R-DDI-450490 https://reactome.org/PathwayBrowser/#/R-DDI-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Dictyostelium discoideum 33697 R-DDI-450517 https://reactome.org/PathwayBrowser/#/R-DDI-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Dictyostelium discoideum 33697 R-DDI-450580 https://reactome.org/PathwayBrowser/#/R-DDI-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Dictyostelium discoideum 33697 R-DDI-68913 https://reactome.org/PathwayBrowser/#/R-DDI-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Dictyostelium discoideum 33697 R-DDI-68950 https://reactome.org/PathwayBrowser/#/R-DDI-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Dictyostelium discoideum 33697 R-DDI-69053 https://reactome.org/PathwayBrowser/#/R-DDI-69053 RFC binding displaces Pol Alpha IEA Dictyostelium discoideum 33697 R-DDI-69063 https://reactome.org/PathwayBrowser/#/R-DDI-69063 Loading of PCNA - Sliding Clamp Formation IEA Dictyostelium discoideum 33697 R-DDI-69068 https://reactome.org/PathwayBrowser/#/R-DDI-69068 RFC dissociates after sliding clamp formation IEA Dictyostelium discoideum 33697 R-DDI-69074 https://reactome.org/PathwayBrowser/#/R-DDI-69074 Formation of Processive Complex IEA Dictyostelium discoideum 33697 R-DDI-69116 https://reactome.org/PathwayBrowser/#/R-DDI-69116 Formation of Okazaki fragments IEA Dictyostelium discoideum 33697 R-DDI-69127 https://reactome.org/PathwayBrowser/#/R-DDI-69127 Formation of the Flap Intermediate IEA Dictyostelium discoideum 33697 R-DDI-69142 https://reactome.org/PathwayBrowser/#/R-DDI-69142 Recruitment of Dna2 endonuclease IEA Dictyostelium discoideum 33697 R-DDI-69152 https://reactome.org/PathwayBrowser/#/R-DDI-69152 Removal of remaining Flap IEA Dictyostelium discoideum 33697 R-DDI-74986 https://reactome.org/PathwayBrowser/#/R-DDI-74986 Elongation of pre-rRNA transcript IEA Dictyostelium discoideum 33697 R-DDI-77077 https://reactome.org/PathwayBrowser/#/R-DDI-77077 Capping complex formation IEA Dictyostelium discoideum 33697 R-DDI-77078 https://reactome.org/PathwayBrowser/#/R-DDI-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Dictyostelium discoideum 33697 R-DDI-77081 https://reactome.org/PathwayBrowser/#/R-DDI-77081 Formation of the CE:GMP intermediate complex IEA Dictyostelium discoideum 33697 R-DDI-77083 https://reactome.org/PathwayBrowser/#/R-DDI-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Dictyostelium discoideum 33697 R-DDI-77085 https://reactome.org/PathwayBrowser/#/R-DDI-77085 Dissociation of transcript with 5'-GMP from GT IEA Dictyostelium discoideum 33697 R-DDI-77090 https://reactome.org/PathwayBrowser/#/R-DDI-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Dictyostelium discoideum 33697 R-DDI-77095 https://reactome.org/PathwayBrowser/#/R-DDI-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Dictyostelium discoideum 33697 R-DDI-77589 https://reactome.org/PathwayBrowser/#/R-DDI-77589 Recognition of AAUAAA sequence by CPSF IEA Dictyostelium discoideum 33697 R-DDI-77590 https://reactome.org/PathwayBrowser/#/R-DDI-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Dictyostelium discoideum 33697 R-DDI-927789 https://reactome.org/PathwayBrowser/#/R-DDI-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Dictyostelium discoideum 33697 R-DDI-927832 https://reactome.org/PathwayBrowser/#/R-DDI-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Dictyostelium discoideum 33697 R-DDI-927889 https://reactome.org/PathwayBrowser/#/R-DDI-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Dictyostelium discoideum 33697 R-DME-112383 https://reactome.org/PathwayBrowser/#/R-DME-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Drosophila melanogaster 33697 R-DME-112385 https://reactome.org/PathwayBrowser/#/R-DME-112385 Addition of nucleotides leads to transcript elongation IEA Drosophila melanogaster 33697 R-DME-112392 https://reactome.org/PathwayBrowser/#/R-DME-112392 Resumption of elongation after recovery from pausing IEA Drosophila melanogaster 33697 R-DME-112395 https://reactome.org/PathwayBrowser/#/R-DME-112395 Abortive termination of elongation after arrest IEA Drosophila melanogaster 33697 R-DME-112396 https://reactome.org/PathwayBrowser/#/R-DME-112396 Separation of elongating transcript from template IEA Drosophila melanogaster 33697 R-DME-113402 https://reactome.org/PathwayBrowser/#/R-DME-113402 Formation of DSIF:NELF:early elongation complex IEA Drosophila melanogaster 33697 R-DME-113407 https://reactome.org/PathwayBrowser/#/R-DME-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Drosophila melanogaster 33697 R-DME-113409 https://reactome.org/PathwayBrowser/#/R-DME-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Drosophila melanogaster 33697 R-DME-113411 https://reactome.org/PathwayBrowser/#/R-DME-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Drosophila melanogaster 33697 R-DME-113412 https://reactome.org/PathwayBrowser/#/R-DME-113412 Pol II elongation complex moves on the template as transcript elongates IEA Drosophila melanogaster 33697 R-DME-113413 https://reactome.org/PathwayBrowser/#/R-DME-113413 TFIIS-mediated recovery of elongation from arrest IEA Drosophila melanogaster 33697 R-DME-113414 https://reactome.org/PathwayBrowser/#/R-DME-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Drosophila melanogaster 33697 R-DME-113504 https://reactome.org/PathwayBrowser/#/R-DME-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Drosophila melanogaster 33697 R-DME-158441 https://reactome.org/PathwayBrowser/#/R-DME-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Drosophila melanogaster 33697 R-DME-158447 https://reactome.org/PathwayBrowser/#/R-DME-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Drosophila melanogaster 33697 R-DME-158481 https://reactome.org/PathwayBrowser/#/R-DME-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Drosophila melanogaster 33697 R-DME-158484 https://reactome.org/PathwayBrowser/#/R-DME-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Drosophila melanogaster 33697 R-DME-159046 https://reactome.org/PathwayBrowser/#/R-DME-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Drosophila melanogaster 33697 R-DME-159050 https://reactome.org/PathwayBrowser/#/R-DME-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Drosophila melanogaster 33697 R-DME-159101 https://reactome.org/PathwayBrowser/#/R-DME-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Drosophila melanogaster 33697 R-DME-2106615 https://reactome.org/PathwayBrowser/#/R-DME-2106615 Removal of siRNA passenger strand IEA Drosophila melanogaster 33697 R-DME-426489 https://reactome.org/PathwayBrowser/#/R-DME-426489 RISC binds inexactly matching target RNAs IEA Drosophila melanogaster 33697 R-DME-426520 https://reactome.org/PathwayBrowser/#/R-DME-426520 Endonucleolytic RISC hydrolyzes target RNAs IEA Drosophila melanogaster 33697 R-DME-426522 https://reactome.org/PathwayBrowser/#/R-DME-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Drosophila melanogaster 33697 R-DME-429961 https://reactome.org/PathwayBrowser/#/R-DME-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Drosophila melanogaster 33697 R-DME-450387 https://reactome.org/PathwayBrowser/#/R-DME-450387 HuR binds the CRM1 nuclear export machinery IEA Drosophila melanogaster 33697 R-DME-450394 https://reactome.org/PathwayBrowser/#/R-DME-450394 p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta IEA Drosophila melanogaster 33697 R-DME-450400 https://reactome.org/PathwayBrowser/#/R-DME-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Drosophila melanogaster 33697 R-DME-450406 https://reactome.org/PathwayBrowser/#/R-DME-450406 p-S92,203-BRF1 binds 14-3-3 IEA Drosophila melanogaster 33697 R-DME-450434 https://reactome.org/PathwayBrowser/#/R-DME-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA IEA Drosophila melanogaster 33697 R-DME-450463 https://reactome.org/PathwayBrowser/#/R-DME-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Drosophila melanogaster 33697 R-DME-450466 https://reactome.org/PathwayBrowser/#/R-DME-450466 AUF1:mRNA complex is destroyed IEA Drosophila melanogaster 33697 R-DME-450474 https://reactome.org/PathwayBrowser/#/R-DME-450474 MK2 phosphorylates BRF1 IEA Drosophila melanogaster 33697 R-DME-450490 https://reactome.org/PathwayBrowser/#/R-DME-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Drosophila melanogaster 33697 R-DME-450494 https://reactome.org/PathwayBrowser/#/R-DME-450494 HuR binds mRNAs in the nucleus IEA Drosophila melanogaster 33697 R-DME-450517 https://reactome.org/PathwayBrowser/#/R-DME-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Drosophila melanogaster 33697 R-DME-450592 https://reactome.org/PathwayBrowser/#/R-DME-450592 KSRP binds AU-rich element in 3' UTR of mRNA IEA Drosophila melanogaster 33697 R-DME-450595 https://reactome.org/PathwayBrowser/#/R-DME-450595 HuR:mRNA complex translocates from the nucleus to the cytosol IEA Drosophila melanogaster 33697 R-DME-482788 https://reactome.org/PathwayBrowser/#/R-DME-482788 p-S54,92,203-BRF1 binds 14-3-3 IEA Drosophila melanogaster 33697 R-DME-517674 https://reactome.org/PathwayBrowser/#/R-DME-517674 p-S158,221-HuR binds mRNA IEA Drosophila melanogaster 33697 R-DME-517705 https://reactome.org/PathwayBrowser/#/R-DME-517705 p-S318,221-HuR binds mRNA IEA Drosophila melanogaster 33697 R-DME-68913 https://reactome.org/PathwayBrowser/#/R-DME-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Drosophila melanogaster 33697 R-DME-68950 https://reactome.org/PathwayBrowser/#/R-DME-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Drosophila melanogaster 33697 R-DME-69053 https://reactome.org/PathwayBrowser/#/R-DME-69053 RFC binding displaces Pol Alpha IEA Drosophila melanogaster 33697 R-DME-69063 https://reactome.org/PathwayBrowser/#/R-DME-69063 Loading of PCNA - Sliding Clamp Formation IEA Drosophila melanogaster 33697 R-DME-69068 https://reactome.org/PathwayBrowser/#/R-DME-69068 RFC dissociates after sliding clamp formation IEA Drosophila melanogaster 33697 R-DME-69127 https://reactome.org/PathwayBrowser/#/R-DME-69127 Formation of the Flap Intermediate IEA Drosophila melanogaster 33697 R-DME-69140 https://reactome.org/PathwayBrowser/#/R-DME-69140 RPA binds to the Flap IEA Drosophila melanogaster 33697 R-DME-69142 https://reactome.org/PathwayBrowser/#/R-DME-69142 Recruitment of Dna2 endonuclease IEA Drosophila melanogaster 33697 R-DME-69144 https://reactome.org/PathwayBrowser/#/R-DME-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Drosophila melanogaster 33697 R-DME-69152 https://reactome.org/PathwayBrowser/#/R-DME-69152 Removal of remaining Flap IEA Drosophila melanogaster 33697 R-DME-72095 https://reactome.org/PathwayBrowser/#/R-DME-72095 Internal Methylation of mRNA IEA Drosophila melanogaster 33697 R-DME-72180 https://reactome.org/PathwayBrowser/#/R-DME-72180 Cleavage of mRNA at the 3'-end IEA Drosophila melanogaster 33697 R-DME-72185 https://reactome.org/PathwayBrowser/#/R-DME-72185 mRNA polyadenylation IEA Drosophila melanogaster 33697 R-DME-74986 https://reactome.org/PathwayBrowser/#/R-DME-74986 Elongation of pre-rRNA transcript IEA Drosophila melanogaster 33697 R-DME-75097 https://reactome.org/PathwayBrowser/#/R-DME-75097 Transport of the export-competent mRNP complex through the NPC IEA Drosophila melanogaster 33697 R-DME-77077 https://reactome.org/PathwayBrowser/#/R-DME-77077 Capping complex formation IEA Drosophila melanogaster 33697 R-DME-77078 https://reactome.org/PathwayBrowser/#/R-DME-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Drosophila melanogaster 33697 R-DME-77081 https://reactome.org/PathwayBrowser/#/R-DME-77081 Formation of the CE:GMP intermediate complex IEA Drosophila melanogaster 33697 R-DME-77083 https://reactome.org/PathwayBrowser/#/R-DME-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Drosophila melanogaster 33697 R-DME-77085 https://reactome.org/PathwayBrowser/#/R-DME-77085 Dissociation of transcript with 5'-GMP from GT IEA Drosophila melanogaster 33697 R-DME-77090 https://reactome.org/PathwayBrowser/#/R-DME-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Drosophila melanogaster 33697 R-DME-77095 https://reactome.org/PathwayBrowser/#/R-DME-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Drosophila melanogaster 33697 R-DME-77589 https://reactome.org/PathwayBrowser/#/R-DME-77589 Recognition of AAUAAA sequence by CPSF IEA Drosophila melanogaster 33697 R-DME-77590 https://reactome.org/PathwayBrowser/#/R-DME-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Drosophila melanogaster 33697 R-DME-77591 https://reactome.org/PathwayBrowser/#/R-DME-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Drosophila melanogaster 33697 R-DME-77592 https://reactome.org/PathwayBrowser/#/R-DME-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Drosophila melanogaster 33697 R-DME-77593 https://reactome.org/PathwayBrowser/#/R-DME-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Drosophila melanogaster 33697 R-DME-77594 https://reactome.org/PathwayBrowser/#/R-DME-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Drosophila melanogaster 33697 R-DME-77615 https://reactome.org/PathwayBrowser/#/R-DME-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Drosophila melanogaster 33697 R-DME-9023909 https://reactome.org/PathwayBrowser/#/R-DME-9023909 C3PO hydrolyzes cleaved passenger strand IEA Drosophila melanogaster 33697 R-DME-927789 https://reactome.org/PathwayBrowser/#/R-DME-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Drosophila melanogaster 33697 R-DME-927832 https://reactome.org/PathwayBrowser/#/R-DME-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Drosophila melanogaster 33697 R-DME-927836 https://reactome.org/PathwayBrowser/#/R-DME-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Drosophila melanogaster 33697 R-DME-927889 https://reactome.org/PathwayBrowser/#/R-DME-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Drosophila melanogaster 33697 R-DME-9833777 https://reactome.org/PathwayBrowser/#/R-DME-9833777 PKR binds activating host RNA IEA Drosophila melanogaster 33697 R-DRE-450406 https://reactome.org/PathwayBrowser/#/R-DRE-450406 p-S92,203-BRF1 binds 14-3-3 IEA Danio rerio 33697 R-DRE-450434 https://reactome.org/PathwayBrowser/#/R-DRE-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA IEA Danio rerio 33697 R-DRE-450466 https://reactome.org/PathwayBrowser/#/R-DRE-450466 AUF1:mRNA complex is destroyed IEA Danio rerio 33697 R-DRE-450474 https://reactome.org/PathwayBrowser/#/R-DRE-450474 MK2 phosphorylates BRF1 IEA Danio rerio 33697 R-DRE-450490 https://reactome.org/PathwayBrowser/#/R-DRE-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Danio rerio 33697 R-DRE-450517 https://reactome.org/PathwayBrowser/#/R-DRE-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Danio rerio 33697 R-DRE-450580 https://reactome.org/PathwayBrowser/#/R-DRE-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Danio rerio 33697 R-DRE-450592 https://reactome.org/PathwayBrowser/#/R-DRE-450592 KSRP binds AU-rich element in 3' UTR of mRNA IEA Danio rerio 33697 R-DRE-482788 https://reactome.org/PathwayBrowser/#/R-DRE-482788 p-S54,92,203-BRF1 binds 14-3-3 IEA Danio rerio 33697 R-DRE-77077 https://reactome.org/PathwayBrowser/#/R-DRE-77077 Capping complex formation IEA Danio rerio 33697 R-DRE-77078 https://reactome.org/PathwayBrowser/#/R-DRE-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Danio rerio 33697 R-DRE-77081 https://reactome.org/PathwayBrowser/#/R-DRE-77081 Formation of the CE:GMP intermediate complex IEA Danio rerio 33697 R-DRE-77083 https://reactome.org/PathwayBrowser/#/R-DRE-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Danio rerio 33697 R-DRE-77085 https://reactome.org/PathwayBrowser/#/R-DRE-77085 Dissociation of transcript with 5'-GMP from GT IEA Danio rerio 33697 R-DRE-927789 https://reactome.org/PathwayBrowser/#/R-DRE-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Danio rerio 33697 R-DRE-927813 https://reactome.org/PathwayBrowser/#/R-DRE-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Danio rerio 33697 R-DRE-927836 https://reactome.org/PathwayBrowser/#/R-DRE-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Danio rerio 33697 R-DRE-927889 https://reactome.org/PathwayBrowser/#/R-DRE-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Danio rerio 33697 R-DRE-9833777 https://reactome.org/PathwayBrowser/#/R-DRE-9833777 PKR binds activating host RNA IEA Danio rerio 33697 R-GGA-1008270 https://reactome.org/PathwayBrowser/#/R-GGA-1008270 Activated TAK1 leaves endosome membrane IEA Gallus gallus 33697 R-GGA-112381 https://reactome.org/PathwayBrowser/#/R-GGA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Gallus gallus 33697 R-GGA-112383 https://reactome.org/PathwayBrowser/#/R-GGA-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Gallus gallus 33697 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus 33697 R-GGA-112392 https://reactome.org/PathwayBrowser/#/R-GGA-112392 Resumption of elongation after recovery from pausing IEA Gallus gallus 33697 R-GGA-112395 https://reactome.org/PathwayBrowser/#/R-GGA-112395 Abortive termination of elongation after arrest IEA Gallus gallus 33697 R-GGA-112396 https://reactome.org/PathwayBrowser/#/R-GGA-112396 Separation of elongating transcript from template IEA Gallus gallus 33697 R-GGA-113402 https://reactome.org/PathwayBrowser/#/R-GGA-113402 Formation of DSIF:NELF:early elongation complex IEA Gallus gallus 33697 R-GGA-113409 https://reactome.org/PathwayBrowser/#/R-GGA-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Gallus gallus 33697 R-GGA-113411 https://reactome.org/PathwayBrowser/#/R-GGA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Gallus gallus 33697 R-GGA-113412 https://reactome.org/PathwayBrowser/#/R-GGA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Gallus gallus 33697 R-GGA-113413 https://reactome.org/PathwayBrowser/#/R-GGA-113413 TFIIS-mediated recovery of elongation from arrest IEA Gallus gallus 33697 R-GGA-113414 https://reactome.org/PathwayBrowser/#/R-GGA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Gallus gallus 33697 R-GGA-113504 https://reactome.org/PathwayBrowser/#/R-GGA-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Gallus gallus 33697 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus 33697 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus 33697 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus 33697 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus 33697 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus 33697 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus 33697 R-GGA-174425 https://reactome.org/PathwayBrowser/#/R-GGA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Gallus gallus 33697 R-GGA-174427 https://reactome.org/PathwayBrowser/#/R-GGA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Gallus gallus 33697 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus 33697 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus 33697 R-GGA-2106615 https://reactome.org/PathwayBrowser/#/R-GGA-2106615 Removal of siRNA passenger strand IEA Gallus gallus 33697 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 33697 R-GGA-426489 https://reactome.org/PathwayBrowser/#/R-GGA-426489 RISC binds inexactly matching target RNAs IEA Gallus gallus 33697 R-GGA-426520 https://reactome.org/PathwayBrowser/#/R-GGA-426520 Endonucleolytic RISC hydrolyzes target RNAs IEA Gallus gallus 33697 R-GGA-426522 https://reactome.org/PathwayBrowser/#/R-GGA-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Gallus gallus 33697 R-GGA-429961 https://reactome.org/PathwayBrowser/#/R-GGA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Gallus gallus 33697 R-GGA-450406 https://reactome.org/PathwayBrowser/#/R-GGA-450406 p-S92,203-BRF1 binds 14-3-3 IEA Gallus gallus 33697 R-GGA-450434 https://reactome.org/PathwayBrowser/#/R-GGA-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA IEA Gallus gallus 33697 R-GGA-450474 https://reactome.org/PathwayBrowser/#/R-GGA-450474 MK2 phosphorylates BRF1 IEA Gallus gallus 33697 R-GGA-450488 https://reactome.org/PathwayBrowser/#/R-GGA-450488 BRF1 Complex recruits RNA degradation activities IEA Gallus gallus 33697 R-GGA-450490 https://reactome.org/PathwayBrowser/#/R-GGA-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Gallus gallus 33697 R-GGA-450494 https://reactome.org/PathwayBrowser/#/R-GGA-450494 HuR binds mRNAs in the nucleus IEA Gallus gallus 33697 R-GGA-450517 https://reactome.org/PathwayBrowser/#/R-GGA-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Gallus gallus 33697 R-GGA-450580 https://reactome.org/PathwayBrowser/#/R-GGA-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Gallus gallus 33697 R-GGA-451439 https://reactome.org/PathwayBrowser/#/R-GGA-451439 Activated TLR7 or 21 recruits MyD88 IEA Gallus gallus 33697 R-GGA-451461 https://reactome.org/PathwayBrowser/#/R-GGA-451461 IRAK4 binds to the activated TLR7 or 21 IEA Gallus gallus 33697 R-GGA-451481 https://reactome.org/PathwayBrowser/#/R-GGA-451481 TLR7 binds to recognized ligands TAS Gallus gallus 33697 R-GGA-482788 https://reactome.org/PathwayBrowser/#/R-GGA-482788 p-S54,92,203-BRF1 binds 14-3-3 IEA Gallus gallus 33697 R-GGA-517674 https://reactome.org/PathwayBrowser/#/R-GGA-517674 p-S158,221-HuR binds mRNA IEA Gallus gallus 33697 R-GGA-517705 https://reactome.org/PathwayBrowser/#/R-GGA-517705 p-S318,221-HuR binds mRNA IEA Gallus gallus 33697 R-GGA-532630 https://reactome.org/PathwayBrowser/#/R-GGA-532630 p-IRAK2- TRAF6 dissociates from the activated TRL7 or 21 IEA Gallus gallus 33697 R-GGA-532632 https://reactome.org/PathwayBrowser/#/R-GGA-532632 TRAF6 binds to p-IRAK2 complexed with activated TLR7 or TLR21 IEA Gallus gallus 33697 R-GGA-571316 https://reactome.org/PathwayBrowser/#/R-GGA-571316 Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. IEA Gallus gallus 33697 R-GGA-571318 https://reactome.org/PathwayBrowser/#/R-GGA-571318 Autoubiquitination of oligoTRAF6 bound to p-IRAK2 IEA Gallus gallus 33697 R-GGA-571324 https://reactome.org/PathwayBrowser/#/R-GGA-571324 IRAK2 binds to p-IRAK4:MyD88:activated TLR7 or 21 complex IEA Gallus gallus 33697 R-GGA-571327 https://reactome.org/PathwayBrowser/#/R-GGA-571327 IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex IEA Gallus gallus 33697 R-GGA-573294 https://reactome.org/PathwayBrowser/#/R-GGA-573294 Activated TRAF6 synthesizes free K63 linked pUb chains. IEA Gallus gallus 33697 R-GGA-573296 https://reactome.org/PathwayBrowser/#/R-GGA-573296 Activated TRAF6 recruits TAK1 kinase complex upon TLR7 or TLR21 stimulation IEA Gallus gallus 33697 R-GGA-68913 https://reactome.org/PathwayBrowser/#/R-GGA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Gallus gallus 33697 R-GGA-68950 https://reactome.org/PathwayBrowser/#/R-GGA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Gallus gallus 33697 R-GGA-69053 https://reactome.org/PathwayBrowser/#/R-GGA-69053 RFC binding displaces Pol Alpha IEA Gallus gallus 33697 R-GGA-69063 https://reactome.org/PathwayBrowser/#/R-GGA-69063 Loading of PCNA - Sliding Clamp Formation IEA Gallus gallus 33697 R-GGA-69068 https://reactome.org/PathwayBrowser/#/R-GGA-69068 RFC dissociates after sliding clamp formation IEA Gallus gallus 33697 R-GGA-72095 https://reactome.org/PathwayBrowser/#/R-GGA-72095 Internal Methylation of mRNA IEA Gallus gallus 33697 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus 33697 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus 33697 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus 33697 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus 33697 R-GGA-77077 https://reactome.org/PathwayBrowser/#/R-GGA-77077 Capping complex formation IEA Gallus gallus 33697 R-GGA-77078 https://reactome.org/PathwayBrowser/#/R-GGA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Gallus gallus 33697 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus 33697 R-GGA-77083 https://reactome.org/PathwayBrowser/#/R-GGA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Gallus gallus 33697 R-GGA-77085 https://reactome.org/PathwayBrowser/#/R-GGA-77085 Dissociation of transcript with 5'-GMP from GT IEA Gallus gallus 33697 R-GGA-77095 https://reactome.org/PathwayBrowser/#/R-GGA-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Gallus gallus 33697 R-GGA-77590 https://reactome.org/PathwayBrowser/#/R-GGA-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Gallus gallus 33697 R-GGA-77591 https://reactome.org/PathwayBrowser/#/R-GGA-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Gallus gallus 33697 R-GGA-77592 https://reactome.org/PathwayBrowser/#/R-GGA-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Gallus gallus 33697 R-GGA-77593 https://reactome.org/PathwayBrowser/#/R-GGA-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Gallus gallus 33697 R-GGA-77608 https://reactome.org/PathwayBrowser/#/R-GGA-77608 Binding of A1CF to stem-looped RNA IEA Gallus gallus 33697 R-GGA-77614 https://reactome.org/PathwayBrowser/#/R-GGA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Gallus gallus 33697 R-GGA-9009936 https://reactome.org/PathwayBrowser/#/R-GGA-9009936 RNASEL cleaves cellular ssRNA IEA Gallus gallus 33697 R-GGA-9023909 https://reactome.org/PathwayBrowser/#/R-GGA-9023909 C3PO hydrolyzes cleaved passenger strand IEA Gallus gallus 33697 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus 33697 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus 33697 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus 33697 R-GGA-9833777 https://reactome.org/PathwayBrowser/#/R-GGA-9833777 PKR binds activating host RNA IEA Gallus gallus 33697 R-GGA-994000 https://reactome.org/PathwayBrowser/#/R-GGA-994000 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation IEA Gallus gallus 33697 R-HSA-112054 https://reactome.org/PathwayBrowser/#/R-HSA-112054 RNA Polymerase III Abortive Initiation At Type 3 Open Promoters IEA Homo sapiens 33697 R-HSA-112055 https://reactome.org/PathwayBrowser/#/R-HSA-112055 RNA Polymerase III Abortive Initiation At Type 1 Open Promoters IEA Homo sapiens 33697 R-HSA-112149 https://reactome.org/PathwayBrowser/#/R-HSA-112149 RNA Polymerase III Abortive Initiation At Type 2 Open Promoters IEA Homo sapiens 33697 R-HSA-112153 https://reactome.org/PathwayBrowser/#/R-HSA-112153 RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters IEA Homo sapiens 33697 R-HSA-112155 https://reactome.org/PathwayBrowser/#/R-HSA-112155 RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters IEA Homo sapiens 33697 R-HSA-112156 https://reactome.org/PathwayBrowser/#/R-HSA-112156 RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters IEA Homo sapiens 33697 R-HSA-112381 https://reactome.org/PathwayBrowser/#/R-HSA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex TAS Homo sapiens 33697 R-HSA-112383 https://reactome.org/PathwayBrowser/#/R-HSA-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein TAS Homo sapiens 33697 R-HSA-112385 https://reactome.org/PathwayBrowser/#/R-HSA-112385 Addition of nucleotides leads to transcript elongation TAS Homo sapiens 33697 R-HSA-112392 https://reactome.org/PathwayBrowser/#/R-HSA-112392 Resumption of elongation after recovery from pausing TAS Homo sapiens 33697 R-HSA-112395 https://reactome.org/PathwayBrowser/#/R-HSA-112395 Abortive termination of elongation after arrest TAS Homo sapiens 33697 R-HSA-112396 https://reactome.org/PathwayBrowser/#/R-HSA-112396 Separation of elongating transcript from template TAS Homo sapiens 33697 R-HSA-113402 https://reactome.org/PathwayBrowser/#/R-HSA-113402 Formation of DSIF:NELF:early elongation complex TAS Homo sapiens 33697 R-HSA-113407 https://reactome.org/PathwayBrowser/#/R-HSA-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) TAS Homo sapiens 33697 R-HSA-113409 https://reactome.org/PathwayBrowser/#/R-HSA-113409 Abortive termination of early transcription elongation by DSIF:NELF TAS Homo sapiens 33697 R-HSA-113411 https://reactome.org/PathwayBrowser/#/R-HSA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing TAS Homo sapiens 33697 R-HSA-113412 https://reactome.org/PathwayBrowser/#/R-HSA-113412 Pol II elongation complex moves on the template as transcript elongates TAS Homo sapiens 33697 R-HSA-113413 https://reactome.org/PathwayBrowser/#/R-HSA-113413 TFIIS-mediated recovery of elongation from arrest TAS Homo sapiens 33697 R-HSA-113414 https://reactome.org/PathwayBrowser/#/R-HSA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest TAS Homo sapiens 33697 R-HSA-113429 https://reactome.org/PathwayBrowser/#/R-HSA-113429 Elongating transcript encounters a lesion in the template TAS Homo sapiens 33697 R-HSA-113442 https://reactome.org/PathwayBrowser/#/R-HSA-113442 RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites IEA Homo sapiens 33697 R-HSA-113446 https://reactome.org/PathwayBrowser/#/R-HSA-113446 Initiation of RNA Polymerase III Productive Transcription IEA Homo sapiens 33697 R-HSA-113449 https://reactome.org/PathwayBrowser/#/R-HSA-113449 RNA Polymerase III Transcriptional Pause at Terminator Sequence IEA Homo sapiens 33697 R-HSA-113451 https://reactome.org/PathwayBrowser/#/R-HSA-113451 Resumption of RNA Polymerase III Productive Transcription IEA Homo sapiens 33697 R-HSA-113454 https://reactome.org/PathwayBrowser/#/R-HSA-113454 RNA Polymerase III Termination and release of transcribed RNA IEA Homo sapiens 33697 R-HSA-113504 https://reactome.org/PathwayBrowser/#/R-HSA-113504 Detection of damage during initiation of DNA synthesis in S-phase TAS Homo sapiens 33697 R-HSA-113705 https://reactome.org/PathwayBrowser/#/R-HSA-113705 RNA Polymerase III Productive Transcription IEA Homo sapiens 33697 R-HSA-158441 https://reactome.org/PathwayBrowser/#/R-HSA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC TAS Homo sapiens 33697 R-HSA-158447 https://reactome.org/PathwayBrowser/#/R-HSA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC TAS Homo sapiens 33697 R-HSA-158481 https://reactome.org/PathwayBrowser/#/R-HSA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC TAS Homo sapiens 33697 R-HSA-158484 https://reactome.org/PathwayBrowser/#/R-HSA-158484 Release of the SLBP independent Histone mRNA from the NPC TAS Homo sapiens 33697 R-HSA-159046 https://reactome.org/PathwayBrowser/#/R-HSA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC TAS Homo sapiens 33697 R-HSA-159050 https://reactome.org/PathwayBrowser/#/R-HSA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex TAS Homo sapiens 33697 R-HSA-159101 https://reactome.org/PathwayBrowser/#/R-HSA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) TAS Homo sapiens 33697 R-HSA-167072 https://reactome.org/PathwayBrowser/#/R-HSA-167072 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Homo sapiens 33697 R-HSA-167076 https://reactome.org/PathwayBrowser/#/R-HSA-167076 2-4 nt.backtracking of Pol II complex on the HIV-1 template leading to elongation pausing IEA Homo sapiens 33697 R-HSA-167077 https://reactome.org/PathwayBrowser/#/R-HSA-167077 Recruitment of elongation factors to form HIV-1 elongation complex IEA Homo sapiens 33697 R-HSA-167083 https://reactome.org/PathwayBrowser/#/R-HSA-167083 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Homo sapiens 33697 R-HSA-167084 https://reactome.org/PathwayBrowser/#/R-HSA-167084 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Homo sapiens 33697 R-HSA-167085 https://reactome.org/PathwayBrowser/#/R-HSA-167085 Formation of DSIF:NELF:HIV-1 early elongation complex IEA Homo sapiens 33697 R-HSA-167087 https://reactome.org/PathwayBrowser/#/R-HSA-167087 Limited elongation of the HIV-1 transcript IEA Homo sapiens 33697 R-HSA-167089 https://reactome.org/PathwayBrowser/#/R-HSA-167089 Recognition and binding of the HIV-1 mRNA cap by the cap-binding complex IEA Homo sapiens 33697 R-HSA-167090 https://reactome.org/PathwayBrowser/#/R-HSA-167090 7-14 nt. Backtracking of Pol II complex on the HIV-1 template leading to elongation arrest IEA Homo sapiens 33697 R-HSA-167147 https://reactome.org/PathwayBrowser/#/R-HSA-167147 Separation of abortive HIV-1 transcript from template IEA Homo sapiens 33697 R-HSA-167148 https://reactome.org/PathwayBrowser/#/R-HSA-167148 TFIIS-mediated recovery of elongation from arrest IEA Homo sapiens 33697 R-HSA-167150 https://reactome.org/PathwayBrowser/#/R-HSA-167150 Resumption of elongation of HIV-1 transcript after recovery from pausing IEA Homo sapiens 33697 R-HSA-167181 https://reactome.org/PathwayBrowser/#/R-HSA-167181 Addition of nucleotides leads to HIV-1 transcript elongation IEA Homo sapiens 33697 R-HSA-167191 https://reactome.org/PathwayBrowser/#/R-HSA-167191 Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex IEA Homo sapiens 33697 R-HSA-167192 https://reactome.org/PathwayBrowser/#/R-HSA-167192 Pol II elongation complex moves on the HIV-1 template as transcript elongates IEA Homo sapiens 33697 R-HSA-167196 https://reactome.org/PathwayBrowser/#/R-HSA-167196 Recruitment of elongation factors to form HIV-1 elongation complex IEA Homo sapiens 33697 R-HSA-167197 https://reactome.org/PathwayBrowser/#/R-HSA-167197 Separation of elongating HIV-1 transcript from template IEA Homo sapiens 33697 R-HSA-167282 https://reactome.org/PathwayBrowser/#/R-HSA-167282 2-4 nt.backtracking of Pol II complex on the HIV-1 template leading to elongation pausing IEA Homo sapiens 33697 R-HSA-167284 https://reactome.org/PathwayBrowser/#/R-HSA-167284 7-14 nt. Backtracking of Pol II complex on the HIV-1 template leading to elongation arrest IEA Homo sapiens 33697 R-HSA-167288 https://reactome.org/PathwayBrowser/#/R-HSA-167288 TFIIS-mediated recovery of HIV-1 elongation from arrest IEA Homo sapiens 33697 R-HSA-167292 https://reactome.org/PathwayBrowser/#/R-HSA-167292 Resumption of elongation of HIV-1 transcript after recovery from pausing IEA Homo sapiens 33697 R-HSA-167459 https://reactome.org/PathwayBrowser/#/R-HSA-167459 Abortive termination of HIV-1 elongation after arrest (Tat-containing elongation complex) IEA Homo sapiens 33697 R-HSA-167478 https://reactome.org/PathwayBrowser/#/R-HSA-167478 Abortive termination of HIV-1 early transcription elongation by DSIF:NELF IEA Homo sapiens 33697 R-HSA-167481 https://reactome.org/PathwayBrowser/#/R-HSA-167481 Abortive termination of HIV-1 elongation after arrest IEA Homo sapiens 33697 R-HSA-167983 https://reactome.org/PathwayBrowser/#/R-HSA-167983 C-ter TLR7 dimer binds TLR7, TLR8 ligands TAS Homo sapiens 33697 R-HSA-168092 https://reactome.org/PathwayBrowser/#/R-HSA-168092 Viral dsRNA binds the Toll-Like Receptor 3 (TLR3) TAS Homo sapiens 33697 R-HSA-168280 https://reactome.org/PathwayBrowser/#/R-HSA-168280 Priming and Initiation of Transcription TAS Homo sapiens 33697 R-HSA-168326 https://reactome.org/PathwayBrowser/#/R-HSA-168326 Assembly of an Active Transcription Complex TAS Homo sapiens 33697 R-HSA-168909 https://reactome.org/PathwayBrowser/#/R-HSA-168909 viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58 bind MAVS TAS Homo sapiens 33697 R-HSA-168910 https://reactome.org/PathwayBrowser/#/R-HSA-168910 RIP1 facilitates IKK complex phosphorylation TAS Homo sapiens 33697 R-HSA-168929 https://reactome.org/PathwayBrowser/#/R-HSA-168929 Viral dsRNA:TLR3 recruits TRIF (TICAM1) TAS Homo sapiens 33697 R-HSA-168930 https://reactome.org/PathwayBrowser/#/R-HSA-168930 Viral dsRNA:TLR3:TRIF complex recruits RIP1 TAS Homo sapiens 33697 R-HSA-168934 https://reactome.org/PathwayBrowser/#/R-HSA-168934 MAVS interacts with RIPK1 and FADD TAS Homo sapiens 33697 R-HSA-168935 https://reactome.org/PathwayBrowser/#/R-HSA-168935 viral dsRNA binds DDX58 TAS Homo sapiens 33697 R-HSA-170704 https://reactome.org/PathwayBrowser/#/R-HSA-170704 Phosphorylation of DSIF by the P-TEFb(Cyclin T1:Cdk9) complex TAS Homo sapiens 33697 R-HSA-170706 https://reactome.org/PathwayBrowser/#/R-HSA-170706 Phosphorylation of NEFL by the P-TEFb(Cyclin T1:Cdk9) complex TAS Homo sapiens 33697 R-HSA-174425 https://reactome.org/PathwayBrowser/#/R-HSA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere TAS Homo sapiens 33697 R-HSA-174427 https://reactome.org/PathwayBrowser/#/R-HSA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere TAS Homo sapiens 33697 R-HSA-174438 https://reactome.org/PathwayBrowser/#/R-HSA-174438 Formation of the Flap Intermediate on the C-strand TAS Homo sapiens 33697 R-HSA-174439 https://reactome.org/PathwayBrowser/#/R-HSA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere TAS Homo sapiens 33697 R-HSA-174444 https://reactome.org/PathwayBrowser/#/R-HSA-174444 Formation of C-strand Okazaki fragments TAS Homo sapiens 33697 R-HSA-174447 https://reactome.org/PathwayBrowser/#/R-HSA-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere TAS Homo sapiens 33697 R-HSA-174448 https://reactome.org/PathwayBrowser/#/R-HSA-174448 Formation of Processive Complex on the C-strand of the telomere TAS Homo sapiens 33697 R-HSA-174452 https://reactome.org/PathwayBrowser/#/R-HSA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere TAS Homo sapiens 33697 R-HSA-177690 https://reactome.org/PathwayBrowser/#/R-HSA-177690 Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex TAS Homo sapiens 33697 R-HSA-177692 https://reactome.org/PathwayBrowser/#/R-HSA-177692 Activation of recruited TAK1 within the activated TLR3 complex TAS Homo sapiens 33697 R-HSA-177694 https://reactome.org/PathwayBrowser/#/R-HSA-177694 Viral dsRNA:TLR3:TICAM1 complex recruits TRAF6 TAS Homo sapiens 33697 R-HSA-192624 https://reactome.org/PathwayBrowser/#/R-HSA-192624 cRNA Extension TAS Homo sapiens 33697 R-HSA-192832 https://reactome.org/PathwayBrowser/#/R-HSA-192832 Initiation of cRNA Synthesis TAS Homo sapiens 33697 R-HSA-192851 https://reactome.org/PathwayBrowser/#/R-HSA-192851 vRNA Extension TAS Homo sapiens 33697 R-HSA-192916 https://reactome.org/PathwayBrowser/#/R-HSA-192916 Initiation of vRNA Synthesis TAS Homo sapiens 33697 R-HSA-2106615 https://reactome.org/PathwayBrowser/#/R-HSA-2106615 Removal of siRNA passenger strand TAS Homo sapiens 33697 R-HSA-210805 https://reactome.org/PathwayBrowser/#/R-HSA-210805 Removal of miRNA passenger strand TAS Homo sapiens 33697 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 33697 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 33697 R-HSA-2187266 https://reactome.org/PathwayBrowser/#/R-HSA-2187266 SCARA5 binds ligands IEA Homo sapiens 33697 R-HSA-2299677 https://reactome.org/PathwayBrowser/#/R-HSA-2299677 SCARA5:ligand is endocytosed IEA Homo sapiens 33697 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 33697 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 33697 R-HSA-426489 https://reactome.org/PathwayBrowser/#/R-HSA-426489 RISC binds inexactly matching target RNAs TAS Homo sapiens 33697 R-HSA-426520 https://reactome.org/PathwayBrowser/#/R-HSA-426520 Endonucleolytic RISC hydrolyzes target RNAs TAS Homo sapiens 33697 R-HSA-426522 https://reactome.org/PathwayBrowser/#/R-HSA-426522 Nonendonucleolytic RISC binds exactly matching target RNAs TAS Homo sapiens 33697 R-HSA-427366 https://reactome.org/PathwayBrowser/#/R-HSA-427366 Transcription of intergenic spacer of the rRNA gene IEA Homo sapiens 33697 R-HSA-427394 https://reactome.org/PathwayBrowser/#/R-HSA-427394 Cleavage of intergenic spacer RNA to yield fragments of 150-300 nucleotides IEA Homo sapiens 33697 R-HSA-427409 https://reactome.org/PathwayBrowser/#/R-HSA-427409 Nucleolar Remodelling Complex (NoRC) binds intergenic region of rDNA IEA Homo sapiens 33697 R-HSA-429961 https://reactome.org/PathwayBrowser/#/R-HSA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA TAS Homo sapiens 33697 R-HSA-433672 https://reactome.org/PathwayBrowser/#/R-HSA-433672 NoRC:HDAC:DNMT deacetylates histone H4 and methylates histone H3 IEA Homo sapiens 33697 R-HSA-450259 https://reactome.org/PathwayBrowser/#/R-HSA-450259 Auto ubiqitination of TRAF6 bound to viral dsRNS:TLR3:TICAM1 complex TAS Homo sapiens 33697 R-HSA-450387 https://reactome.org/PathwayBrowser/#/R-HSA-450387 HuR binds the CRM1 nuclear export machinery TAS Homo sapiens 33697 R-HSA-450394 https://reactome.org/PathwayBrowser/#/R-HSA-450394 p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta TAS Homo sapiens 33697 R-HSA-450400 https://reactome.org/PathwayBrowser/#/R-HSA-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs TAS Homo sapiens 33697 R-HSA-450406 https://reactome.org/PathwayBrowser/#/R-HSA-450406 p-S92,203-BRF1 binds 14-3-3 TAS Homo sapiens 33697 R-HSA-450422 https://reactome.org/PathwayBrowser/#/R-HSA-450422 KSRP recruits RNA degradation activities TAS Homo sapiens 33697 R-HSA-450431 https://reactome.org/PathwayBrowser/#/R-HSA-450431 ZFP36 (TTP) recruits RNA degradation activities TAS Homo sapiens 33697 R-HSA-450434 https://reactome.org/PathwayBrowser/#/R-HSA-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA TAS Homo sapiens 33697 R-HSA-450463 https://reactome.org/PathwayBrowser/#/R-HSA-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) TAS Homo sapiens 33697 R-HSA-450466 https://reactome.org/PathwayBrowser/#/R-HSA-450466 AUF1:mRNA complex is destroyed TAS Homo sapiens 33697 R-HSA-450474 https://reactome.org/PathwayBrowser/#/R-HSA-450474 MK2 phosphorylates BRF1 TAS Homo sapiens 33697 R-HSA-450488 https://reactome.org/PathwayBrowser/#/R-HSA-450488 BRF1 Complex recruits RNA degradation activities TAS Homo sapiens 33697 R-HSA-450490 https://reactome.org/PathwayBrowser/#/R-HSA-450490 Protein Kinase B/Akt phosphorylates BRF1 TAS Homo sapiens 33697 R-HSA-450494 https://reactome.org/PathwayBrowser/#/R-HSA-450494 HuR binds mRNAs in the nucleus TAS Homo sapiens 33697 R-HSA-450517 https://reactome.org/PathwayBrowser/#/R-HSA-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA TAS Homo sapiens 33697 R-HSA-450551 https://reactome.org/PathwayBrowser/#/R-HSA-450551 AUF1 binds translation and heat shock proteins TAS Homo sapiens 33697 R-HSA-450580 https://reactome.org/PathwayBrowser/#/R-HSA-450580 AUF1 (hnRNP D0) is ubiquitinylated TAS Homo sapiens 33697 R-HSA-450592 https://reactome.org/PathwayBrowser/#/R-HSA-450592 KSRP binds AU-rich element in 3' UTR of mRNA TAS Homo sapiens 33697 R-HSA-450595 https://reactome.org/PathwayBrowser/#/R-HSA-450595 HuR:mRNA complex translocates from the nucleus to the cytosol TAS Homo sapiens 33697 R-HSA-482788 https://reactome.org/PathwayBrowser/#/R-HSA-482788 p-S54,92,203-BRF1 binds 14-3-3 TAS Homo sapiens 33697 R-HSA-517674 https://reactome.org/PathwayBrowser/#/R-HSA-517674 p-S158,221-HuR binds mRNA TAS Homo sapiens 33697 R-HSA-517705 https://reactome.org/PathwayBrowser/#/R-HSA-517705 p-S318,221-HuR binds mRNA TAS Homo sapiens 33697 R-HSA-517731 https://reactome.org/PathwayBrowser/#/R-HSA-517731 Expression of IL-8 TAS Homo sapiens 33697 R-HSA-5227490 https://reactome.org/PathwayBrowser/#/R-HSA-5227490 NoRC:HDAC:DNMT methylates cytosine of the rRNA genes IEA Homo sapiens 33697 R-HSA-5578712 https://reactome.org/PathwayBrowser/#/R-HSA-5578712 Importin-8 binds AGO2:miRNA TAS Homo sapiens 33697 R-HSA-5578742 https://reactome.org/PathwayBrowser/#/R-HSA-5578742 AGO1,2:small RNA complexes interact with chromatin TAS Homo sapiens 33697 R-HSA-5578744 https://reactome.org/PathwayBrowser/#/R-HSA-5578744 Importin-8 imports AGO2:miRNA into the nucleus TAS Homo sapiens 33697 R-HSA-5578965 https://reactome.org/PathwayBrowser/#/R-HSA-5578965 TNRC6A binds AGO2:miRNA TAS Homo sapiens 33697 R-HSA-5578966 https://reactome.org/PathwayBrowser/#/R-HSA-5578966 TNRC6A:AGO2:miRNA is transported into the nucleus TAS Homo sapiens 33697 R-HSA-5601883 https://reactome.org/PathwayBrowser/#/R-HSA-5601883 Complexed PIWIL4 binds cleaved transposon RNA IEA Homo sapiens 33697 R-HSA-5601887 https://reactome.org/PathwayBrowser/#/R-HSA-5601887 PLD6 dimer cleaves primary piRNA transcript to pre-piRNA IEA Homo sapiens 33697 R-HSA-5601888 https://reactome.org/PathwayBrowser/#/R-HSA-5601888 Unknown nuclease cleaves pre-piRNA in 4xMeR-PIWIL1:pre-piRNA:TDRD6:TDRKH IEA Homo sapiens 33697 R-HSA-5601897 https://reactome.org/PathwayBrowser/#/R-HSA-5601897 MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events IEA Homo sapiens 33697 R-HSA-5601910 https://reactome.org/PathwayBrowser/#/R-HSA-5601910 Complexed PIWIL2:2'-O-methyl-piRNA cleaves transposon RNA IEA Homo sapiens 33697 R-HSA-5601919 https://reactome.org/PathwayBrowser/#/R-HSA-5601919 Unknown nuclease cleaves cleaved transposon RNA bound in MeR-PIWIL4:cleaved transposon RNA:TDRD9:MAEL:TDRKH IEA Homo sapiens 33697 R-HSA-5601922 https://reactome.org/PathwayBrowser/#/R-HSA-5601922 Complexed PIWIL2 binds cleaved transposon RNA IEA Homo sapiens 33697 R-HSA-5601924 https://reactome.org/PathwayBrowser/#/R-HSA-5601924 Primary piRNA transcript translocates from nucleoplasm to cytosol TAS Homo sapiens 33697 R-HSA-5601926 https://reactome.org/PathwayBrowser/#/R-HSA-5601926 RNA polymerase II polymerizes primary piRNA transcript IEA Homo sapiens 33697 R-HSA-5601929 https://reactome.org/PathwayBrowser/#/R-HSA-5601929 Unknown nuclease cleaves cleaved transposon RNA in 6xMeR-PIWIL2:cleaved transposon RNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1 IEA Homo sapiens 33697 R-HSA-5602624 https://reactome.org/PathwayBrowser/#/R-HSA-5602624 Defective TRAF3 does not transmit the signal TAS Homo sapiens 33697 R-HSA-5602712 https://reactome.org/PathwayBrowser/#/R-HSA-5602712 TICAM1 deficiency blocks TLR3 pathway TAS Homo sapiens 33697 R-HSA-5603062 https://reactome.org/PathwayBrowser/#/R-HSA-5603062 Complexed PIWIL2 binds pre-piRNA IEA Homo sapiens 33697 R-HSA-5603067 https://reactome.org/PathwayBrowser/#/R-HSA-5603067 Unknown nuclease cleaves pre-piRNA in ASZ1:DDX4:MOV10L1:6xMeR-PIWIL2:pre-piRNA:TDRD1:TDRD12 IEA Homo sapiens 33697 R-HSA-5615682 https://reactome.org/PathwayBrowser/#/R-HSA-5615682 Complexed PIWIL1 binds pre-piRNA IEA Homo sapiens 33697 R-HSA-5629203 https://reactome.org/PathwayBrowser/#/R-HSA-5629203 HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-PIWIL1:piRNA:TDRD6:TDRKH IEA Homo sapiens 33697 R-HSA-5629218 https://reactome.org/PathwayBrowser/#/R-HSA-5629218 HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1 IEA Homo sapiens 33697 R-HSA-5629237 https://reactome.org/PathwayBrowser/#/R-HSA-5629237 HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH IEA Homo sapiens 33697 R-HSA-6790905 https://reactome.org/PathwayBrowser/#/R-HSA-6790905 Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA TAS Homo sapiens 33697 R-HSA-6790907 https://reactome.org/PathwayBrowser/#/R-HSA-6790907 Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides IEA Homo sapiens 33697 R-HSA-68913 https://reactome.org/PathwayBrowser/#/R-HSA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin TAS Homo sapiens 33697 R-HSA-68950 https://reactome.org/PathwayBrowser/#/R-HSA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin TAS Homo sapiens 33697 R-HSA-69053 https://reactome.org/PathwayBrowser/#/R-HSA-69053 RFC binding displaces Pol Alpha TAS Homo sapiens 33697 R-HSA-69063 https://reactome.org/PathwayBrowser/#/R-HSA-69063 Loading of PCNA - Sliding Clamp Formation TAS Homo sapiens 33697 R-HSA-69068 https://reactome.org/PathwayBrowser/#/R-HSA-69068 RFC dissociates after sliding clamp formation TAS Homo sapiens 33697 R-HSA-69074 https://reactome.org/PathwayBrowser/#/R-HSA-69074 Formation of Processive Complex TAS Homo sapiens 33697 R-HSA-69116 https://reactome.org/PathwayBrowser/#/R-HSA-69116 Formation of Okazaki fragments TAS Homo sapiens 33697 R-HSA-69127 https://reactome.org/PathwayBrowser/#/R-HSA-69127 Formation of the Flap Intermediate TAS Homo sapiens 33697 R-HSA-69140 https://reactome.org/PathwayBrowser/#/R-HSA-69140 RPA binds to the Flap TAS Homo sapiens 33697 R-HSA-69142 https://reactome.org/PathwayBrowser/#/R-HSA-69142 Recruitment of Dna2 endonuclease TAS Homo sapiens 33697 R-HSA-69144 https://reactome.org/PathwayBrowser/#/R-HSA-69144 Removal of RNA primer and dissociation of RPA and Dna2 TAS Homo sapiens 33697 R-HSA-69152 https://reactome.org/PathwayBrowser/#/R-HSA-69152 Removal of remaining Flap TAS Homo sapiens 33697 R-HSA-72095 https://reactome.org/PathwayBrowser/#/R-HSA-72095 Internal Methylation of mRNA TAS Homo sapiens 33697 R-HSA-72180 https://reactome.org/PathwayBrowser/#/R-HSA-72180 Cleavage of mRNA at the 3'-end TAS Homo sapiens 33697 R-HSA-72185 https://reactome.org/PathwayBrowser/#/R-HSA-72185 mRNA polyadenylation TAS Homo sapiens 33697 R-HSA-74986 https://reactome.org/PathwayBrowser/#/R-HSA-74986 Elongation of pre-rRNA transcript TAS Homo sapiens 33697 R-HSA-75083 https://reactome.org/PathwayBrowser/#/R-HSA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation TAS Homo sapiens 33697 R-HSA-75096 https://reactome.org/PathwayBrowser/#/R-HSA-75096 Docking of the TAP:EJC Complex with the NPC TAS Homo sapiens 33697 R-HSA-75097 https://reactome.org/PathwayBrowser/#/R-HSA-75097 Transport of the export-competent mRNP complex through the NPC TAS Homo sapiens 33697 R-HSA-77077 https://reactome.org/PathwayBrowser/#/R-HSA-77077 Capping complex formation TAS Homo sapiens 33697 R-HSA-77078 https://reactome.org/PathwayBrowser/#/R-HSA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme TAS Homo sapiens 33697 R-HSA-77081 https://reactome.org/PathwayBrowser/#/R-HSA-77081 Formation of the CE:GMP intermediate complex TAS Homo sapiens 33697 R-HSA-77083 https://reactome.org/PathwayBrowser/#/R-HSA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA TAS Homo sapiens 33697 R-HSA-77085 https://reactome.org/PathwayBrowser/#/R-HSA-77085 Dissociation of transcript with 5'-GMP from GT TAS Homo sapiens 33697 R-HSA-77090 https://reactome.org/PathwayBrowser/#/R-HSA-77090 Methylation of GMP-cap by RNA Methyltransferase TAS Homo sapiens 33697 R-HSA-77095 https://reactome.org/PathwayBrowser/#/R-HSA-77095 Recognition and binding of the mRNA cap by the cap-binding complex TAS Homo sapiens 33697 R-HSA-77589 https://reactome.org/PathwayBrowser/#/R-HSA-77589 Recognition of AAUAAA sequence by CPSF TAS Homo sapiens 33697 R-HSA-77590 https://reactome.org/PathwayBrowser/#/R-HSA-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA TAS Homo sapiens 33697 R-HSA-77591 https://reactome.org/PathwayBrowser/#/R-HSA-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex TAS Homo sapiens 33697 R-HSA-77592 https://reactome.org/PathwayBrowser/#/R-HSA-77592 Cleavage of Intronless Pre-mRNA at 3'-end TAS Homo sapiens 33697 R-HSA-77593 https://reactome.org/PathwayBrowser/#/R-HSA-77593 Cleavage and polyadenylation of Intronless Pre-mRNA TAS Homo sapiens 33697 R-HSA-77594 https://reactome.org/PathwayBrowser/#/R-HSA-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC TAS Homo sapiens 33697 R-HSA-77607 https://reactome.org/PathwayBrowser/#/R-HSA-77607 Formation of stem-loop structure in ApoB mRNA TAS Homo sapiens 33697 R-HSA-77608 https://reactome.org/PathwayBrowser/#/R-HSA-77608 Binding of A1CF to stem-looped RNA TAS Homo sapiens 33697 R-HSA-77609 https://reactome.org/PathwayBrowser/#/R-HSA-77609 Binding of APOBEC-1 to form editosome TAS Homo sapiens 33697 R-HSA-77612 https://reactome.org/PathwayBrowser/#/R-HSA-77612 Formation of dsRNA structure by looping TAS Homo sapiens 33697 R-HSA-77614 https://reactome.org/PathwayBrowser/#/R-HSA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) TAS Homo sapiens 33697 R-HSA-77615 https://reactome.org/PathwayBrowser/#/R-HSA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) TAS Homo sapiens 33697 R-HSA-83677 https://reactome.org/PathwayBrowser/#/R-HSA-83677 C4 deamination of cytidine TAS Homo sapiens 33697 R-HSA-847070 https://reactome.org/PathwayBrowser/#/R-HSA-847070 Phosphorylated TAK1 dissociates from the TLR3 receptor complex TAS Homo sapiens 33697 R-HSA-8849157 https://reactome.org/PathwayBrowser/#/R-HSA-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally TAS Homo sapiens 33697 R-HSA-8983671 https://reactome.org/PathwayBrowser/#/R-HSA-8983671 OAS1 binds viral dsRNA TAS Homo sapiens 33697 R-HSA-8983680 https://reactome.org/PathwayBrowser/#/R-HSA-8983680 OAS1 produces oligoadenylates TAS Homo sapiens 33697 R-HSA-8983688 https://reactome.org/PathwayBrowser/#/R-HSA-8983688 OAS1 oligomerizes TAS Homo sapiens 33697 R-HSA-8985091 https://reactome.org/PathwayBrowser/#/R-HSA-8985091 OAS3 produces oligoadenylates TAS Homo sapiens 33697 R-HSA-8985157 https://reactome.org/PathwayBrowser/#/R-HSA-8985157 OAS3 binds viral dsRNA TAS Homo sapiens 33697 R-HSA-9009936 https://reactome.org/PathwayBrowser/#/R-HSA-9009936 RNASEL cleaves cellular ssRNA TAS Homo sapiens 33697 R-HSA-9009941 https://reactome.org/PathwayBrowser/#/R-HSA-9009941 RNASEL cleaves viral ssRNA TAS Homo sapiens 33697 R-HSA-9013889 https://reactome.org/PathwayBrowser/#/R-HSA-9013889 TLR3-induced ripoptosome assembly TAS Homo sapiens 33697 R-HSA-9013895 https://reactome.org/PathwayBrowser/#/R-HSA-9013895 Caspase-8 processing within TLR3 complex TAS Homo sapiens 33697 R-HSA-9013963 https://reactome.org/PathwayBrowser/#/R-HSA-9013963 RIP3 binds TICAM1 within TLR3 complex to mediate necroptosis TAS Homo sapiens 33697 R-HSA-9013974 https://reactome.org/PathwayBrowser/#/R-HSA-9013974 Auto-ubiquitination of TRAF3 within activated TLR3 complex TAS Homo sapiens 33697 R-HSA-9013978 https://reactome.org/PathwayBrowser/#/R-HSA-9013978 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex TAS Homo sapiens 33697 R-HSA-9013979 https://reactome.org/PathwayBrowser/#/R-HSA-9013979 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR3 TAS Homo sapiens 33697 R-HSA-9013985 https://reactome.org/PathwayBrowser/#/R-HSA-9013985 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR3 TAS Homo sapiens 33697 R-HSA-9013990 https://reactome.org/PathwayBrowser/#/R-HSA-9013990 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TICAM1:TLR3:viral dsRNA TAS Homo sapiens 33697 R-HSA-9013992 https://reactome.org/PathwayBrowser/#/R-HSA-9013992 TRAF3 binds to TRIF:activated TLR3 complex TAS Homo sapiens 33697 R-HSA-9014320 https://reactome.org/PathwayBrowser/#/R-HSA-9014320 SARM binds viral dsRNA:TLR3:TICAM1 TAS Homo sapiens 33697 R-HSA-9014342 https://reactome.org/PathwayBrowser/#/R-HSA-9014342 K63-linked ubiquitination of RIP1 bound to the activated TLR complex TAS Homo sapiens 33697 R-HSA-9014343 https://reactome.org/PathwayBrowser/#/R-HSA-9014343 IKBKG subunit of IKK complex binds K63pUb- RIP1 within the TLR3 complex TAS Homo sapiens 33697 R-HSA-9023909 https://reactome.org/PathwayBrowser/#/R-HSA-9023909 C3PO hydrolyzes cleaved passenger strand TAS Homo sapiens 33697 R-HSA-918224 https://reactome.org/PathwayBrowser/#/R-HSA-918224 DDX58 is K63 polyubiquitinated TAS Homo sapiens 33697 R-HSA-918225 https://reactome.org/PathwayBrowser/#/R-HSA-918225 TBK1/IKK epsilon complex interacts with MAVS bound TRAF3 TAS Homo sapiens 33697 R-HSA-918227 https://reactome.org/PathwayBrowser/#/R-HSA-918227 Recruitment of TRAF3 to MAVS TAS Homo sapiens 33697 R-HSA-918229 https://reactome.org/PathwayBrowser/#/R-HSA-918229 Phosphorylation and release of IRF3/IRF7 TAS Homo sapiens 33697 R-HSA-918230 https://reactome.org/PathwayBrowser/#/R-HSA-918230 Recruitment of TRAF6/TRAF2 to IPS-1 TAS Homo sapiens 33697 R-HSA-918232 https://reactome.org/PathwayBrowser/#/R-HSA-918232 Recruitment of IRF3,IRF7 TAS Homo sapiens 33697 R-HSA-927789 https://reactome.org/PathwayBrowser/#/R-HSA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex TAS Homo sapiens 33697 R-HSA-927813 https://reactome.org/PathwayBrowser/#/R-HSA-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A TAS Homo sapiens 33697 R-HSA-927830 https://reactome.org/PathwayBrowser/#/R-HSA-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex TAS Homo sapiens 33697 R-HSA-927832 https://reactome.org/PathwayBrowser/#/R-HSA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex TAS Homo sapiens 33697 R-HSA-927836 https://reactome.org/PathwayBrowser/#/R-HSA-927836 SMG6 hydrolyzes mRNA with premature termination codon TAS Homo sapiens 33697 R-HSA-927889 https://reactome.org/PathwayBrowser/#/R-HSA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) TAS Homo sapiens 33697 R-HSA-933523 https://reactome.org/PathwayBrowser/#/R-HSA-933523 Dimerzation of procaspase-8, procaspase-10 TAS Homo sapiens 33697 R-HSA-933525 https://reactome.org/PathwayBrowser/#/R-HSA-933525 Phosphorylation and release of IRF7 TAS Homo sapiens 33697 R-HSA-933526 https://reactome.org/PathwayBrowser/#/R-HSA-933526 Recruitment of caspase-8 and -10 to FADD complex TAS Homo sapiens 33697 R-HSA-933527 https://reactome.org/PathwayBrowser/#/R-HSA-933527 Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6 TAS Homo sapiens 33697 R-HSA-933528 https://reactome.org/PathwayBrowser/#/R-HSA-933528 Interaction of MEKK1 with TRAF6 IEA Homo sapiens 33697 R-HSA-933530 https://reactome.org/PathwayBrowser/#/R-HSA-933530 Activation of IKK by MEKK1 TAS Homo sapiens 33697 R-HSA-933532 https://reactome.org/PathwayBrowser/#/R-HSA-933532 Processing of caspases TAS Homo sapiens 33697 R-HSA-933537 https://reactome.org/PathwayBrowser/#/R-HSA-933537 Recruitment of TANK to TRAF6 TAS Homo sapiens 33697 R-HSA-933538 https://reactome.org/PathwayBrowser/#/R-HSA-933538 Recruitment of IRF7 to TRAF6 TAS Homo sapiens 33697 R-HSA-933539 https://reactome.org/PathwayBrowser/#/R-HSA-933539 Recruitment of IKK complex TAS Homo sapiens 33697 R-HSA-936378 https://reactome.org/PathwayBrowser/#/R-HSA-936378 Inhibition of DDX58/IFIH1 signaling by ATG5:ATG12:MAVS IEA Homo sapiens 33697 R-HSA-936381 https://reactome.org/PathwayBrowser/#/R-HSA-936381 OTUD5 deubiquitinates TRAF3 TAS Homo sapiens 33697 R-HSA-936475 https://reactome.org/PathwayBrowser/#/R-HSA-936475 Negative regulation of DDX58/IFIH1 signaling by RNF216 TAS Homo sapiens 33697 R-HSA-937343 https://reactome.org/PathwayBrowser/#/R-HSA-937343 NLRC5 interacts with DDX58/IFIH1 TAS Homo sapiens 33697 R-HSA-9628444 https://reactome.org/PathwayBrowser/#/R-HSA-9628444 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation TAS Homo sapiens 33697 R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 33697 R-HSA-9681651 https://reactome.org/PathwayBrowser/#/R-HSA-9681651 nsp8 generates RNA primers TAS Homo sapiens 33697 R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 33697 R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 33697 R-HSA-9691204 https://reactome.org/PathwayBrowser/#/R-HSA-9691204 TLR8 dimer binds TLR7, TLR8 ligands TAS Homo sapiens 33697 R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 33697 R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 33697 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 33697 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 33697 R-HSA-9705137 https://reactome.org/PathwayBrowser/#/R-HSA-9705137 TBK1 or IKBKE forms homodimers TAS Homo sapiens 33697 R-HSA-9705145 https://reactome.org/PathwayBrowser/#/R-HSA-9705145 TBK1, IKBKE form homodimers TAS Homo sapiens 33697 R-HSA-9705320 https://reactome.org/PathwayBrowser/#/R-HSA-9705320 TBK1, IKBKE are autophosphorylated at Ser172 TAS Homo sapiens 33697 R-HSA-9705323 https://reactome.org/PathwayBrowser/#/R-HSA-9705323 Phosphorylation of TBK1/IKBKE TAS Homo sapiens 33697 R-HSA-9710480 https://reactome.org/PathwayBrowser/#/R-HSA-9710480 Decitabine triphosphate incorporates into DNA TAS Homo sapiens 33697 R-HSA-975098 https://reactome.org/PathwayBrowser/#/R-HSA-975098 MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 TAS Homo sapiens 33697 R-HSA-975100 https://reactome.org/PathwayBrowser/#/R-HSA-975100 Dissociation of hp-IRAK1/or IRAK2:TRAF6-oligomer from the p-IRAK4 :oligo-Myd88:activated TLR7/8 or 9 complex TAS Homo sapiens 33697 R-HSA-975106 https://reactome.org/PathwayBrowser/#/R-HSA-975106 Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 33697 R-HSA-975111 https://reactome.org/PathwayBrowser/#/R-HSA-975111 TRAF6 binds to hp- IRAK1/or p-IRAK2:p-IRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 33697 R-HSA-975115 https://reactome.org/PathwayBrowser/#/R-HSA-975115 IRAK1/or IRAK2 binds to the activated IRAK4 :MyD88:activated TLR 7/8 or 9. TAS Homo sapiens 33697 R-HSA-975118 https://reactome.org/PathwayBrowser/#/R-HSA-975118 TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex TAS Homo sapiens 33697 R-HSA-975125 https://reactome.org/PathwayBrowser/#/R-HSA-975125 Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 33697 R-HSA-975134 https://reactome.org/PathwayBrowser/#/R-HSA-975134 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 TAS Homo sapiens 33697 R-HSA-975156 https://reactome.org/PathwayBrowser/#/R-HSA-975156 IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex TAS Homo sapiens 33697 R-HSA-975160 https://reactome.org/PathwayBrowser/#/R-HSA-975160 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 TAS Homo sapiens 33697 R-HSA-975170 https://reactome.org/PathwayBrowser/#/R-HSA-975170 IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 33697 R-HSA-975175 https://reactome.org/PathwayBrowser/#/R-HSA-975175 MyD88 interacts with the activated TLR receptor 7, 8 or 9 TAS Homo sapiens 33697 R-HSA-975180 https://reactome.org/PathwayBrowser/#/R-HSA-975180 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 33697 R-HSA-975188 https://reactome.org/PathwayBrowser/#/R-HSA-975188 TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 33697 R-HSA-9754830 https://reactome.org/PathwayBrowser/#/R-HSA-9754830 TLR8 dimer binds SARS-CoV-2 GU-rich ssRNA TAS Homo sapiens 33697 R-HSA-9755765 https://reactome.org/PathwayBrowser/#/R-HSA-9755765 C-ter TLR7 dimer binds SARS-CoV-2 GU-rich ssRNA TAS Homo sapiens 33697 R-HSA-9770847 https://reactome.org/PathwayBrowser/#/R-HSA-9770847 Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) TAS Homo sapiens 33697 R-HSA-9772351 https://reactome.org/PathwayBrowser/#/R-HSA-9772351 Disassembly of the Intron Lariat Spliceosome (new) TAS Homo sapiens 33697 R-HSA-9828196 https://reactome.org/PathwayBrowser/#/R-HSA-9828196 TBK1 binds K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR3 TAS Homo sapiens 33697 R-HSA-9828200 https://reactome.org/PathwayBrowser/#/R-HSA-9828200 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 TAS Homo sapiens 33697 R-HSA-9828204 https://reactome.org/PathwayBrowser/#/R-HSA-9828204 IKKε (IKBKE) binds K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR3 TAS Homo sapiens 33697 R-HSA-9828205 https://reactome.org/PathwayBrowser/#/R-HSA-9828205 TBK1 is phosphorylated within the activated TLR3 complex TAS Homo sapiens 33697 R-HSA-9828209 https://reactome.org/PathwayBrowser/#/R-HSA-9828209 OPTN binds TBK1 within the activated TLR3 complex TAS Homo sapiens 33697 R-HSA-9830706 https://reactome.org/PathwayBrowser/#/R-HSA-9830706 IKKε (IKBKE) is phosphorylated within the activated TLR3 complex TAS Homo sapiens 33697 R-HSA-9830710 https://reactome.org/PathwayBrowser/#/R-HSA-9830710 IKKε (IKBKE) is ubiquitinated within the activated TLR3 complex TAS Homo sapiens 33697 R-HSA-9833723 https://reactome.org/PathwayBrowser/#/R-HSA-9833723 PKR forms a dimer TAS Homo sapiens 33697 R-HSA-9833777 https://reactome.org/PathwayBrowser/#/R-HSA-9833777 PKR binds activating host RNA TAS Homo sapiens 33697 R-HSA-9839016 https://reactome.org/PathwayBrowser/#/R-HSA-9839016 PKR binds viral dsRNA TAS Homo sapiens 33697 R-HSA-990526 https://reactome.org/PathwayBrowser/#/R-HSA-990526 Recruitment of ITCH and K48 ubiquitination of MAVS TAS Homo sapiens 33697 R-HSA-990528 https://reactome.org/PathwayBrowser/#/R-HSA-990528 Interaction of PCBP2 with MAVS TAS Homo sapiens 33697 R-MMU-112381 https://reactome.org/PathwayBrowser/#/R-MMU-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Mus musculus 33697 R-MMU-112383 https://reactome.org/PathwayBrowser/#/R-MMU-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Mus musculus 33697 R-MMU-112385 https://reactome.org/PathwayBrowser/#/R-MMU-112385 Addition of nucleotides leads to transcript elongation IEA Mus musculus 33697 R-MMU-112392 https://reactome.org/PathwayBrowser/#/R-MMU-112392 Resumption of elongation after recovery from pausing IEA Mus musculus 33697 R-MMU-112395 https://reactome.org/PathwayBrowser/#/R-MMU-112395 Abortive termination of elongation after arrest IEA Mus musculus 33697 R-MMU-112396 https://reactome.org/PathwayBrowser/#/R-MMU-112396 Separation of elongating transcript from template IEA Mus musculus 33697 R-MMU-113402 https://reactome.org/PathwayBrowser/#/R-MMU-113402 Formation of DSIF:NELF:early elongation complex IEA Mus musculus 33697 R-MMU-113407 https://reactome.org/PathwayBrowser/#/R-MMU-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Mus musculus 33697 R-MMU-113409 https://reactome.org/PathwayBrowser/#/R-MMU-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Mus musculus 33697 R-MMU-113411 https://reactome.org/PathwayBrowser/#/R-MMU-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Mus musculus 33697 R-MMU-113412 https://reactome.org/PathwayBrowser/#/R-MMU-113412 Pol II elongation complex moves on the template as transcript elongates IEA Mus musculus 33697 R-MMU-113413 https://reactome.org/PathwayBrowser/#/R-MMU-113413 TFIIS-mediated recovery of elongation from arrest IEA Mus musculus 33697 R-MMU-113414 https://reactome.org/PathwayBrowser/#/R-MMU-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Mus musculus 33697 R-MMU-113429 https://reactome.org/PathwayBrowser/#/R-MMU-113429 Elongating transcript encounters a lesion in the template IEA Mus musculus 33697 R-MMU-113504 https://reactome.org/PathwayBrowser/#/R-MMU-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Mus musculus 33697 R-MMU-158441 https://reactome.org/PathwayBrowser/#/R-MMU-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Mus musculus 33697 R-MMU-158447 https://reactome.org/PathwayBrowser/#/R-MMU-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Mus musculus 33697 R-MMU-158481 https://reactome.org/PathwayBrowser/#/R-MMU-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Mus musculus 33697 R-MMU-158484 https://reactome.org/PathwayBrowser/#/R-MMU-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Mus musculus 33697 R-MMU-159046 https://reactome.org/PathwayBrowser/#/R-MMU-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Mus musculus 33697 R-MMU-159050 https://reactome.org/PathwayBrowser/#/R-MMU-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Mus musculus 33697 R-MMU-159101 https://reactome.org/PathwayBrowser/#/R-MMU-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Mus musculus 33697 R-MMU-174425 https://reactome.org/PathwayBrowser/#/R-MMU-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Mus musculus 33697 R-MMU-174427 https://reactome.org/PathwayBrowser/#/R-MMU-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Mus musculus 33697 R-MMU-174438 https://reactome.org/PathwayBrowser/#/R-MMU-174438 Formation of the Flap Intermediate on the C-strand IEA Mus musculus 33697 R-MMU-174439 https://reactome.org/PathwayBrowser/#/R-MMU-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Mus musculus 33697 R-MMU-174444 https://reactome.org/PathwayBrowser/#/R-MMU-174444 Formation of C-strand Okazaki fragments IEA Mus musculus 33697 R-MMU-174447 https://reactome.org/PathwayBrowser/#/R-MMU-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Mus musculus 33697 R-MMU-174448 https://reactome.org/PathwayBrowser/#/R-MMU-174448 Formation of Processive Complex on the C-strand of the telomere IEA Mus musculus 33697 R-MMU-174452 https://reactome.org/PathwayBrowser/#/R-MMU-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Mus musculus 33697 R-MMU-2106615 https://reactome.org/PathwayBrowser/#/R-MMU-2106615 Removal of siRNA passenger strand IEA Mus musculus 33697 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 33697 R-MMU-2187267 https://reactome.org/PathwayBrowser/#/R-MMU-2187267 Scara5 binds ligands TAS Mus musculus 33697 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 33697 R-MMU-426489 https://reactome.org/PathwayBrowser/#/R-MMU-426489 RISC binds inexactly matching target RNAs IEA Mus musculus 33697 R-MMU-426520 https://reactome.org/PathwayBrowser/#/R-MMU-426520 Endonucleolytic RISC hydrolyzes target RNAs IEA Mus musculus 33697 R-MMU-426522 https://reactome.org/PathwayBrowser/#/R-MMU-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Mus musculus 33697 R-MMU-429961 https://reactome.org/PathwayBrowser/#/R-MMU-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Mus musculus 33697 R-MMU-450387 https://reactome.org/PathwayBrowser/#/R-MMU-450387 HuR binds the CRM1 nuclear export machinery IEA Mus musculus 33697 R-MMU-450394 https://reactome.org/PathwayBrowser/#/R-MMU-450394 p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta IEA Mus musculus 33697 R-MMU-450400 https://reactome.org/PathwayBrowser/#/R-MMU-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Mus musculus 33697 R-MMU-450406 https://reactome.org/PathwayBrowser/#/R-MMU-450406 p-S92,203-BRF1 binds 14-3-3 IEA Mus musculus 33697 R-MMU-450422 https://reactome.org/PathwayBrowser/#/R-MMU-450422 KSRP recruits RNA degradation activities IEA Mus musculus 33697 R-MMU-450431 https://reactome.org/PathwayBrowser/#/R-MMU-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Mus musculus 33697 R-MMU-450434 https://reactome.org/PathwayBrowser/#/R-MMU-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA IEA Mus musculus 33697 R-MMU-450463 https://reactome.org/PathwayBrowser/#/R-MMU-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Mus musculus 33697 R-MMU-450466 https://reactome.org/PathwayBrowser/#/R-MMU-450466 AUF1:mRNA complex is destroyed IEA Mus musculus 33697 R-MMU-450474 https://reactome.org/PathwayBrowser/#/R-MMU-450474 MK2 phosphorylates BRF1 IEA Mus musculus 33697 R-MMU-450488 https://reactome.org/PathwayBrowser/#/R-MMU-450488 BRF1 Complex recruits RNA degradation activities IEA Mus musculus 33697 R-MMU-450490 https://reactome.org/PathwayBrowser/#/R-MMU-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Mus musculus 33697 R-MMU-450494 https://reactome.org/PathwayBrowser/#/R-MMU-450494 HuR binds mRNAs in the nucleus IEA Mus musculus 33697 R-MMU-450517 https://reactome.org/PathwayBrowser/#/R-MMU-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Mus musculus 33697 R-MMU-450551 https://reactome.org/PathwayBrowser/#/R-MMU-450551 AUF1 binds translation and heat shock proteins IEA Mus musculus 33697 R-MMU-450580 https://reactome.org/PathwayBrowser/#/R-MMU-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Mus musculus 33697 R-MMU-450592 https://reactome.org/PathwayBrowser/#/R-MMU-450592 KSRP binds AU-rich element in 3' UTR of mRNA IEA Mus musculus 33697 R-MMU-450595 https://reactome.org/PathwayBrowser/#/R-MMU-450595 HuR:mRNA complex translocates from the nucleus to the cytosol IEA Mus musculus 33697 R-MMU-482788 https://reactome.org/PathwayBrowser/#/R-MMU-482788 p-S54,92,203-BRF1 binds 14-3-3 IEA Mus musculus 33697 R-MMU-517674 https://reactome.org/PathwayBrowser/#/R-MMU-517674 p-S158,221-HuR binds mRNA IEA Mus musculus 33697 R-MMU-517705 https://reactome.org/PathwayBrowser/#/R-MMU-517705 p-S318,221-HuR binds mRNA IEA Mus musculus 33697 R-MMU-5605205 https://reactome.org/PathwayBrowser/#/R-MMU-5605205 Unknown nuclease cleaves pre-piRNA in Asz1:Ddx4:Mov10l1:6xMeR-Piwil2:pre-piRNA:Tdrd1:Tdrd12 TAS Mus musculus 33697 R-MMU-5605213 https://reactome.org/PathwayBrowser/#/R-MMU-5605213 Complexed Piwil2 binds cleaved transposon RNA TAS Mus musculus 33697 R-MMU-5605262 https://reactome.org/PathwayBrowser/#/R-MMU-5605262 Pld6 dimer cleaves primary piRNA transcript to pre-piRNA TAS Mus musculus 33697 R-MMU-5605279 https://reactome.org/PathwayBrowser/#/R-MMU-5605279 Complexed Piwil2 binds pre-piRNA TAS Mus musculus 33697 R-MMU-5605301 https://reactome.org/PathwayBrowser/#/R-MMU-5605301 RNA polymerase II polymerizes primary piRNA transcript TAS Mus musculus 33697 R-MMU-5605344 https://reactome.org/PathwayBrowser/#/R-MMU-5605344 Unknown nuclease cleaves pre-piRNA in 4xMeR-Piwil1:pre-piRNA:Tdrd6:Tdrkh TAS Mus musculus 33697 R-MMU-5605349 https://reactome.org/PathwayBrowser/#/R-MMU-5605349 Complexed Piwil2:2'-O-methyl-piRNA cleaves transposon RNA TAS Mus musculus 33697 R-MMU-5606210 https://reactome.org/PathwayBrowser/#/R-MMU-5606210 Unknown nuclease cleaves cleaved transposon RNA in MeR-Piwil4:cleaved transposon RNA:Tdrd9:Mael:Tdrkh TAS Mus musculus 33697 R-MMU-5606226 https://reactome.org/PathwayBrowser/#/R-MMU-5606226 Unknown nuclease cleaves cleaved transposon RNA in Asz1:Ddx4:Mov10l1:6xMeR-Piwil2:piRNA:Tdrd1:Tdrd12 TAS Mus musculus 33697 R-MMU-5606252 https://reactome.org/PathwayBrowser/#/R-MMU-5606252 Complexed Piwil4 binds cleaved transposon RNA TAS Mus musculus 33697 R-MMU-5606256 https://reactome.org/PathwayBrowser/#/R-MMU-5606256 MeR-Piwil4:2'-O-methyl-piRNA:Tdrd9:Mael:Tdrkh dissociates and MeR-Piwil4:2'-O-methyl-piRNA, Tdrd9, Mael translocate from cytosol to nucleus in unknown association and unknown order of events TAS Mus musculus 33697 R-MMU-5615685 https://reactome.org/PathwayBrowser/#/R-MMU-5615685 Complexed Piwil1 binds pre-piRNA TAS Mus musculus 33697 R-MMU-5629217 https://reactome.org/PathwayBrowser/#/R-MMU-5629217 Henmt1 methylates 2' hydroxyl at 3' end of piRNA in Asz1:Ddx4:Mov10l1:6xMeR-Piwil2:piRNA:Tdrd1:Tdrd12 TAS Mus musculus 33697 R-MMU-5629230 https://reactome.org/PathwayBrowser/#/R-MMU-5629230 Henmt1 methylates 2' hydroxyl at 3' end of piRNA in MeR-Piwil4:piRNA:Tdrd9:Mael:Tdrkh TAS Mus musculus 33697 R-MMU-5629239 https://reactome.org/PathwayBrowser/#/R-MMU-5629239 Henmt1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-Piwil1:piRNA:Tdrd6:Tdrkh TAS Mus musculus 33697 R-MMU-68913 https://reactome.org/PathwayBrowser/#/R-MMU-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Mus musculus 33697 R-MMU-68950 https://reactome.org/PathwayBrowser/#/R-MMU-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Mus musculus 33697 R-MMU-69053 https://reactome.org/PathwayBrowser/#/R-MMU-69053 RFC binding displaces Pol Alpha IEA Mus musculus 33697 R-MMU-69063 https://reactome.org/PathwayBrowser/#/R-MMU-69063 Loading of PCNA - Sliding Clamp Formation IEA Mus musculus 33697 R-MMU-69068 https://reactome.org/PathwayBrowser/#/R-MMU-69068 RFC dissociates after sliding clamp formation IEA Mus musculus 33697 R-MMU-69074 https://reactome.org/PathwayBrowser/#/R-MMU-69074 Formation of Processive Complex IEA Mus musculus 33697 R-MMU-69116 https://reactome.org/PathwayBrowser/#/R-MMU-69116 Formation of Okazaki fragments IEA Mus musculus 33697 R-MMU-69127 https://reactome.org/PathwayBrowser/#/R-MMU-69127 Formation of the Flap Intermediate IEA Mus musculus 33697 R-MMU-69140 https://reactome.org/PathwayBrowser/#/R-MMU-69140 RPA binds to the Flap IEA Mus musculus 33697 R-MMU-69142 https://reactome.org/PathwayBrowser/#/R-MMU-69142 Recruitment of Dna2 endonuclease IEA Mus musculus 33697 R-MMU-69144 https://reactome.org/PathwayBrowser/#/R-MMU-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Mus musculus 33697 R-MMU-69152 https://reactome.org/PathwayBrowser/#/R-MMU-69152 Removal of remaining Flap IEA Mus musculus 33697 R-MMU-72095 https://reactome.org/PathwayBrowser/#/R-MMU-72095 Internal Methylation of mRNA IEA Mus musculus 33697 R-MMU-72180 https://reactome.org/PathwayBrowser/#/R-MMU-72180 Cleavage of mRNA at the 3'-end IEA Mus musculus 33697 R-MMU-72185 https://reactome.org/PathwayBrowser/#/R-MMU-72185 mRNA polyadenylation IEA Mus musculus 33697 R-MMU-74986 https://reactome.org/PathwayBrowser/#/R-MMU-74986 Elongation of pre-rRNA transcript IEA Mus musculus 33697 R-MMU-75083 https://reactome.org/PathwayBrowser/#/R-MMU-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Mus musculus 33697 R-MMU-75097 https://reactome.org/PathwayBrowser/#/R-MMU-75097 Transport of the export-competent mRNP complex through the NPC IEA Mus musculus 33697 R-MMU-77077 https://reactome.org/PathwayBrowser/#/R-MMU-77077 Capping complex formation IEA Mus musculus 33697 R-MMU-77078 https://reactome.org/PathwayBrowser/#/R-MMU-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Mus musculus 33697 R-MMU-77081 https://reactome.org/PathwayBrowser/#/R-MMU-77081 Formation of the CE:GMP intermediate complex IEA Mus musculus 33697 R-MMU-77083 https://reactome.org/PathwayBrowser/#/R-MMU-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Mus musculus 33697 R-MMU-77085 https://reactome.org/PathwayBrowser/#/R-MMU-77085 Dissociation of transcript with 5'-GMP from GT IEA Mus musculus 33697 R-MMU-77090 https://reactome.org/PathwayBrowser/#/R-MMU-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Mus musculus 33697 R-MMU-77095 https://reactome.org/PathwayBrowser/#/R-MMU-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Mus musculus 33697 R-MMU-77589 https://reactome.org/PathwayBrowser/#/R-MMU-77589 Recognition of AAUAAA sequence by CPSF IEA Mus musculus 33697 R-MMU-77590 https://reactome.org/PathwayBrowser/#/R-MMU-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Mus musculus 33697 R-MMU-77591 https://reactome.org/PathwayBrowser/#/R-MMU-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Mus musculus 33697 R-MMU-77592 https://reactome.org/PathwayBrowser/#/R-MMU-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Mus musculus 33697 R-MMU-77593 https://reactome.org/PathwayBrowser/#/R-MMU-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Mus musculus 33697 R-MMU-77594 https://reactome.org/PathwayBrowser/#/R-MMU-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Mus musculus 33697 R-MMU-77608 https://reactome.org/PathwayBrowser/#/R-MMU-77608 Binding of A1CF to stem-looped RNA IEA Mus musculus 33697 R-MMU-77609 https://reactome.org/PathwayBrowser/#/R-MMU-77609 Binding of APOBEC-1 to form editosome IEA Mus musculus 33697 R-MMU-77614 https://reactome.org/PathwayBrowser/#/R-MMU-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Mus musculus 33697 R-MMU-77615 https://reactome.org/PathwayBrowser/#/R-MMU-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Mus musculus 33697 R-MMU-83677 https://reactome.org/PathwayBrowser/#/R-MMU-83677 C4 deamination of cytidine IEA Mus musculus 33697 R-MMU-8849157 https://reactome.org/PathwayBrowser/#/R-MMU-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Mus musculus 33697 R-MMU-9009936 https://reactome.org/PathwayBrowser/#/R-MMU-9009936 RNASEL cleaves cellular ssRNA IEA Mus musculus 33697 R-MMU-9023909 https://reactome.org/PathwayBrowser/#/R-MMU-9023909 C3PO hydrolyzes cleaved passenger strand IEA Mus musculus 33697 R-MMU-927789 https://reactome.org/PathwayBrowser/#/R-MMU-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Mus musculus 33697 R-MMU-927813 https://reactome.org/PathwayBrowser/#/R-MMU-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Mus musculus 33697 R-MMU-927830 https://reactome.org/PathwayBrowser/#/R-MMU-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex IEA Mus musculus 33697 R-MMU-927832 https://reactome.org/PathwayBrowser/#/R-MMU-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Mus musculus 33697 R-MMU-927836 https://reactome.org/PathwayBrowser/#/R-MMU-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Mus musculus 33697 R-MMU-927889 https://reactome.org/PathwayBrowser/#/R-MMU-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Mus musculus 33697 R-MMU-9833777 https://reactome.org/PathwayBrowser/#/R-MMU-9833777 PKR binds activating host RNA IEA Mus musculus 33697 R-PFA-113407 https://reactome.org/PathwayBrowser/#/R-PFA-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Plasmodium falciparum 33697 R-PFA-113409 https://reactome.org/PathwayBrowser/#/R-PFA-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Plasmodium falciparum 33697 R-PFA-113504 https://reactome.org/PathwayBrowser/#/R-PFA-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Plasmodium falciparum 33697 R-PFA-450434 https://reactome.org/PathwayBrowser/#/R-PFA-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA IEA Plasmodium falciparum 33697 R-PFA-450466 https://reactome.org/PathwayBrowser/#/R-PFA-450466 AUF1:mRNA complex is destroyed IEA Plasmodium falciparum 33697 R-PFA-450580 https://reactome.org/PathwayBrowser/#/R-PFA-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Plasmodium falciparum 33697 R-PFA-68913 https://reactome.org/PathwayBrowser/#/R-PFA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Plasmodium falciparum 33697 R-PFA-68950 https://reactome.org/PathwayBrowser/#/R-PFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Plasmodium falciparum 33697 R-PFA-69053 https://reactome.org/PathwayBrowser/#/R-PFA-69053 RFC binding displaces Pol Alpha IEA Plasmodium falciparum 33697 R-PFA-69063 https://reactome.org/PathwayBrowser/#/R-PFA-69063 Loading of PCNA - Sliding Clamp Formation IEA Plasmodium falciparum 33697 R-PFA-69068 https://reactome.org/PathwayBrowser/#/R-PFA-69068 RFC dissociates after sliding clamp formation IEA Plasmodium falciparum 33697 R-PFA-69127 https://reactome.org/PathwayBrowser/#/R-PFA-69127 Formation of the Flap Intermediate IEA Plasmodium falciparum 33697 R-PFA-69140 https://reactome.org/PathwayBrowser/#/R-PFA-69140 RPA binds to the Flap IEA Plasmodium falciparum 33697 R-PFA-69152 https://reactome.org/PathwayBrowser/#/R-PFA-69152 Removal of remaining Flap IEA Plasmodium falciparum 33697 R-PFA-72095 https://reactome.org/PathwayBrowser/#/R-PFA-72095 Internal Methylation of mRNA IEA Plasmodium falciparum 33697 R-PFA-77077 https://reactome.org/PathwayBrowser/#/R-PFA-77077 Capping complex formation IEA Plasmodium falciparum 33697 R-PFA-77078 https://reactome.org/PathwayBrowser/#/R-PFA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Plasmodium falciparum 33697 R-PFA-77081 https://reactome.org/PathwayBrowser/#/R-PFA-77081 Formation of the CE:GMP intermediate complex IEA Plasmodium falciparum 33697 R-PFA-77083 https://reactome.org/PathwayBrowser/#/R-PFA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Plasmodium falciparum 33697 R-PFA-77085 https://reactome.org/PathwayBrowser/#/R-PFA-77085 Dissociation of transcript with 5'-GMP from GT IEA Plasmodium falciparum 33697 R-PFA-927789 https://reactome.org/PathwayBrowser/#/R-PFA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Plasmodium falciparum 33697 R-PFA-927889 https://reactome.org/PathwayBrowser/#/R-PFA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Plasmodium falciparum 33697 R-RNO-112381 https://reactome.org/PathwayBrowser/#/R-RNO-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Rattus norvegicus 33697 R-RNO-112383 https://reactome.org/PathwayBrowser/#/R-RNO-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Rattus norvegicus 33697 R-RNO-112385 https://reactome.org/PathwayBrowser/#/R-RNO-112385 Addition of nucleotides leads to transcript elongation IEA Rattus norvegicus 33697 R-RNO-112392 https://reactome.org/PathwayBrowser/#/R-RNO-112392 Resumption of elongation after recovery from pausing IEA Rattus norvegicus 33697 R-RNO-112395 https://reactome.org/PathwayBrowser/#/R-RNO-112395 Abortive termination of elongation after arrest IEA Rattus norvegicus 33697 R-RNO-112396 https://reactome.org/PathwayBrowser/#/R-RNO-112396 Separation of elongating transcript from template IEA Rattus norvegicus 33697 R-RNO-113402 https://reactome.org/PathwayBrowser/#/R-RNO-113402 Formation of DSIF:NELF:early elongation complex IEA Rattus norvegicus 33697 R-RNO-113407 https://reactome.org/PathwayBrowser/#/R-RNO-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Rattus norvegicus 33697 R-RNO-113409 https://reactome.org/PathwayBrowser/#/R-RNO-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Rattus norvegicus 33697 R-RNO-113411 https://reactome.org/PathwayBrowser/#/R-RNO-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Rattus norvegicus 33697 R-RNO-113412 https://reactome.org/PathwayBrowser/#/R-RNO-113412 Pol II elongation complex moves on the template as transcript elongates IEA Rattus norvegicus 33697 R-RNO-113413 https://reactome.org/PathwayBrowser/#/R-RNO-113413 TFIIS-mediated recovery of elongation from arrest IEA Rattus norvegicus 33697 R-RNO-113414 https://reactome.org/PathwayBrowser/#/R-RNO-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Rattus norvegicus 33697 R-RNO-113429 https://reactome.org/PathwayBrowser/#/R-RNO-113429 Elongating transcript encounters a lesion in the template IEA Rattus norvegicus 33697 R-RNO-113504 https://reactome.org/PathwayBrowser/#/R-RNO-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Rattus norvegicus 33697 R-RNO-158441 https://reactome.org/PathwayBrowser/#/R-RNO-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Rattus norvegicus 33697 R-RNO-158447 https://reactome.org/PathwayBrowser/#/R-RNO-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Rattus norvegicus 33697 R-RNO-158481 https://reactome.org/PathwayBrowser/#/R-RNO-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Rattus norvegicus 33697 R-RNO-158484 https://reactome.org/PathwayBrowser/#/R-RNO-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Rattus norvegicus 33697 R-RNO-159046 https://reactome.org/PathwayBrowser/#/R-RNO-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Rattus norvegicus 33697 R-RNO-159050 https://reactome.org/PathwayBrowser/#/R-RNO-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Rattus norvegicus 33697 R-RNO-159101 https://reactome.org/PathwayBrowser/#/R-RNO-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Rattus norvegicus 33697 R-RNO-174425 https://reactome.org/PathwayBrowser/#/R-RNO-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Rattus norvegicus 33697 R-RNO-174427 https://reactome.org/PathwayBrowser/#/R-RNO-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Rattus norvegicus 33697 R-RNO-174438 https://reactome.org/PathwayBrowser/#/R-RNO-174438 Formation of the Flap Intermediate on the C-strand IEA Rattus norvegicus 33697 R-RNO-174439 https://reactome.org/PathwayBrowser/#/R-RNO-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Rattus norvegicus 33697 R-RNO-174444 https://reactome.org/PathwayBrowser/#/R-RNO-174444 Formation of C-strand Okazaki fragments IEA Rattus norvegicus 33697 R-RNO-174447 https://reactome.org/PathwayBrowser/#/R-RNO-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Rattus norvegicus 33697 R-RNO-174448 https://reactome.org/PathwayBrowser/#/R-RNO-174448 Formation of Processive Complex on the C-strand of the telomere IEA Rattus norvegicus 33697 R-RNO-174452 https://reactome.org/PathwayBrowser/#/R-RNO-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Rattus norvegicus 33697 R-RNO-2106615 https://reactome.org/PathwayBrowser/#/R-RNO-2106615 Removal of siRNA passenger strand IEA Rattus norvegicus 33697 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 33697 R-RNO-426489 https://reactome.org/PathwayBrowser/#/R-RNO-426489 RISC binds inexactly matching target RNAs IEA Rattus norvegicus 33697 R-RNO-426520 https://reactome.org/PathwayBrowser/#/R-RNO-426520 Endonucleolytic RISC hydrolyzes target RNAs IEA Rattus norvegicus 33697 R-RNO-426522 https://reactome.org/PathwayBrowser/#/R-RNO-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Rattus norvegicus 33697 R-RNO-429961 https://reactome.org/PathwayBrowser/#/R-RNO-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Rattus norvegicus 33697 R-RNO-450387 https://reactome.org/PathwayBrowser/#/R-RNO-450387 HuR binds the CRM1 nuclear export machinery IEA Rattus norvegicus 33697 R-RNO-450394 https://reactome.org/PathwayBrowser/#/R-RNO-450394 p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta IEA Rattus norvegicus 33697 R-RNO-450400 https://reactome.org/PathwayBrowser/#/R-RNO-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Rattus norvegicus 33697 R-RNO-450406 https://reactome.org/PathwayBrowser/#/R-RNO-450406 p-S92,203-BRF1 binds 14-3-3 IEA Rattus norvegicus 33697 R-RNO-450422 https://reactome.org/PathwayBrowser/#/R-RNO-450422 KSRP recruits RNA degradation activities IEA Rattus norvegicus 33697 R-RNO-450431 https://reactome.org/PathwayBrowser/#/R-RNO-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Rattus norvegicus 33697 R-RNO-450434 https://reactome.org/PathwayBrowser/#/R-RNO-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA IEA Rattus norvegicus 33697 R-RNO-450463 https://reactome.org/PathwayBrowser/#/R-RNO-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Rattus norvegicus 33697 R-RNO-450466 https://reactome.org/PathwayBrowser/#/R-RNO-450466 AUF1:mRNA complex is destroyed IEA Rattus norvegicus 33697 R-RNO-450474 https://reactome.org/PathwayBrowser/#/R-RNO-450474 MK2 phosphorylates BRF1 IEA Rattus norvegicus 33697 R-RNO-450488 https://reactome.org/PathwayBrowser/#/R-RNO-450488 BRF1 Complex recruits RNA degradation activities IEA Rattus norvegicus 33697 R-RNO-450490 https://reactome.org/PathwayBrowser/#/R-RNO-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Rattus norvegicus 33697 R-RNO-450494 https://reactome.org/PathwayBrowser/#/R-RNO-450494 HuR binds mRNAs in the nucleus IEA Rattus norvegicus 33697 R-RNO-450517 https://reactome.org/PathwayBrowser/#/R-RNO-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Rattus norvegicus 33697 R-RNO-450551 https://reactome.org/PathwayBrowser/#/R-RNO-450551 AUF1 binds translation and heat shock proteins IEA Rattus norvegicus 33697 R-RNO-450580 https://reactome.org/PathwayBrowser/#/R-RNO-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Rattus norvegicus 33697 R-RNO-450592 https://reactome.org/PathwayBrowser/#/R-RNO-450592 KSRP binds AU-rich element in 3' UTR of mRNA IEA Rattus norvegicus 33697 R-RNO-450595 https://reactome.org/PathwayBrowser/#/R-RNO-450595 HuR:mRNA complex translocates from the nucleus to the cytosol IEA Rattus norvegicus 33697 R-RNO-482788 https://reactome.org/PathwayBrowser/#/R-RNO-482788 p-S54,92,203-BRF1 binds 14-3-3 IEA Rattus norvegicus 33697 R-RNO-517674 https://reactome.org/PathwayBrowser/#/R-RNO-517674 p-S158,221-HuR binds mRNA IEA Rattus norvegicus 33697 R-RNO-517705 https://reactome.org/PathwayBrowser/#/R-RNO-517705 p-S318,221-HuR binds mRNA IEA Rattus norvegicus 33697 R-RNO-68913 https://reactome.org/PathwayBrowser/#/R-RNO-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Rattus norvegicus 33697 R-RNO-68950 https://reactome.org/PathwayBrowser/#/R-RNO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Rattus norvegicus 33697 R-RNO-69053 https://reactome.org/PathwayBrowser/#/R-RNO-69053 RFC binding displaces Pol Alpha IEA Rattus norvegicus 33697 R-RNO-69063 https://reactome.org/PathwayBrowser/#/R-RNO-69063 Loading of PCNA - Sliding Clamp Formation IEA Rattus norvegicus 33697 R-RNO-69068 https://reactome.org/PathwayBrowser/#/R-RNO-69068 RFC dissociates after sliding clamp formation IEA Rattus norvegicus 33697 R-RNO-69074 https://reactome.org/PathwayBrowser/#/R-RNO-69074 Formation of Processive Complex IEA Rattus norvegicus 33697 R-RNO-69116 https://reactome.org/PathwayBrowser/#/R-RNO-69116 Formation of Okazaki fragments IEA Rattus norvegicus 33697 R-RNO-69127 https://reactome.org/PathwayBrowser/#/R-RNO-69127 Formation of the Flap Intermediate IEA Rattus norvegicus 33697 R-RNO-69140 https://reactome.org/PathwayBrowser/#/R-RNO-69140 RPA binds to the Flap IEA Rattus norvegicus 33697 R-RNO-69142 https://reactome.org/PathwayBrowser/#/R-RNO-69142 Recruitment of Dna2 endonuclease IEA Rattus norvegicus 33697 R-RNO-69144 https://reactome.org/PathwayBrowser/#/R-RNO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Rattus norvegicus 33697 R-RNO-69152 https://reactome.org/PathwayBrowser/#/R-RNO-69152 Removal of remaining Flap IEA Rattus norvegicus 33697 R-RNO-72095 https://reactome.org/PathwayBrowser/#/R-RNO-72095 Internal Methylation of mRNA IEA Rattus norvegicus 33697 R-RNO-72180 https://reactome.org/PathwayBrowser/#/R-RNO-72180 Cleavage of mRNA at the 3'-end IEA Rattus norvegicus 33697 R-RNO-72185 https://reactome.org/PathwayBrowser/#/R-RNO-72185 mRNA polyadenylation IEA Rattus norvegicus 33697 R-RNO-74986 https://reactome.org/PathwayBrowser/#/R-RNO-74986 Elongation of pre-rRNA transcript IEA Rattus norvegicus 33697 R-RNO-75083 https://reactome.org/PathwayBrowser/#/R-RNO-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Rattus norvegicus 33697 R-RNO-75097 https://reactome.org/PathwayBrowser/#/R-RNO-75097 Transport of the export-competent mRNP complex through the NPC IEA Rattus norvegicus 33697 R-RNO-77077 https://reactome.org/PathwayBrowser/#/R-RNO-77077 Capping complex formation IEA Rattus norvegicus 33697 R-RNO-77078 https://reactome.org/PathwayBrowser/#/R-RNO-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Rattus norvegicus 33697 R-RNO-77081 https://reactome.org/PathwayBrowser/#/R-RNO-77081 Formation of the CE:GMP intermediate complex IEA Rattus norvegicus 33697 R-RNO-77083 https://reactome.org/PathwayBrowser/#/R-RNO-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Rattus norvegicus 33697 R-RNO-77085 https://reactome.org/PathwayBrowser/#/R-RNO-77085 Dissociation of transcript with 5'-GMP from GT IEA Rattus norvegicus 33697 R-RNO-77090 https://reactome.org/PathwayBrowser/#/R-RNO-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Rattus norvegicus 33697 R-RNO-77095 https://reactome.org/PathwayBrowser/#/R-RNO-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Rattus norvegicus 33697 R-RNO-77589 https://reactome.org/PathwayBrowser/#/R-RNO-77589 Recognition of AAUAAA sequence by CPSF IEA Rattus norvegicus 33697 R-RNO-77590 https://reactome.org/PathwayBrowser/#/R-RNO-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Rattus norvegicus 33697 R-RNO-77591 https://reactome.org/PathwayBrowser/#/R-RNO-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Rattus norvegicus 33697 R-RNO-77592 https://reactome.org/PathwayBrowser/#/R-RNO-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Rattus norvegicus 33697 R-RNO-77593 https://reactome.org/PathwayBrowser/#/R-RNO-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Rattus norvegicus 33697 R-RNO-77594 https://reactome.org/PathwayBrowser/#/R-RNO-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Rattus norvegicus 33697 R-RNO-77608 https://reactome.org/PathwayBrowser/#/R-RNO-77608 Binding of A1CF to stem-looped RNA IEA Rattus norvegicus 33697 R-RNO-77609 https://reactome.org/PathwayBrowser/#/R-RNO-77609 Binding of APOBEC-1 to form editosome IEA Rattus norvegicus 33697 R-RNO-77614 https://reactome.org/PathwayBrowser/#/R-RNO-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Rattus norvegicus 33697 R-RNO-77615 https://reactome.org/PathwayBrowser/#/R-RNO-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Rattus norvegicus 33697 R-RNO-83677 https://reactome.org/PathwayBrowser/#/R-RNO-83677 C4 deamination of cytidine IEA Rattus norvegicus 33697 R-RNO-9009936 https://reactome.org/PathwayBrowser/#/R-RNO-9009936 RNASEL cleaves cellular ssRNA IEA Rattus norvegicus 33697 R-RNO-9023909 https://reactome.org/PathwayBrowser/#/R-RNO-9023909 C3PO hydrolyzes cleaved passenger strand IEA Rattus norvegicus 33697 R-RNO-927789 https://reactome.org/PathwayBrowser/#/R-RNO-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Rattus norvegicus 33697 R-RNO-927813 https://reactome.org/PathwayBrowser/#/R-RNO-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Rattus norvegicus 33697 R-RNO-927830 https://reactome.org/PathwayBrowser/#/R-RNO-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex IEA Rattus norvegicus 33697 R-RNO-927832 https://reactome.org/PathwayBrowser/#/R-RNO-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Rattus norvegicus 33697 R-RNO-927836 https://reactome.org/PathwayBrowser/#/R-RNO-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Rattus norvegicus 33697 R-RNO-927889 https://reactome.org/PathwayBrowser/#/R-RNO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Rattus norvegicus 33697 R-RNO-9833777 https://reactome.org/PathwayBrowser/#/R-RNO-9833777 PKR binds activating host RNA IEA Rattus norvegicus 33697 R-SCE-111942 https://reactome.org/PathwayBrowser/#/R-SCE-111942 RNA Polymerase III Initiation At a Simple Start Sequence TAS Saccharomyces cerevisiae 33697 R-SCE-111943 https://reactome.org/PathwayBrowser/#/R-SCE-111943 RNA Polymerase III Abortive Initiation TAS Saccharomyces cerevisiae 33697 R-SCE-111945 https://reactome.org/PathwayBrowser/#/R-SCE-111945 Beginning of RNA Polymerase III Productive Transcription TAS Saccharomyces cerevisiae 33697 R-SCE-111946 https://reactome.org/PathwayBrowser/#/R-SCE-111946 RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites TAS Saccharomyces cerevisiae 33697 R-SCE-112383 https://reactome.org/PathwayBrowser/#/R-SCE-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Saccharomyces cerevisiae 33697 R-SCE-112466 https://reactome.org/PathwayBrowser/#/R-SCE-112466 RNA Polymerase III Transcriptional Pause at Terminator Sequence TAS Saccharomyces cerevisiae 33697 R-SCE-112480 https://reactome.org/PathwayBrowser/#/R-SCE-112480 RNA Polymerase III Termination and release of transcribed RNA TAS Saccharomyces cerevisiae 33697 R-SCE-113407 https://reactome.org/PathwayBrowser/#/R-SCE-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Saccharomyces cerevisiae 33697 R-SCE-113409 https://reactome.org/PathwayBrowser/#/R-SCE-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Saccharomyces cerevisiae 33697 R-SCE-113504 https://reactome.org/PathwayBrowser/#/R-SCE-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Saccharomyces cerevisiae 33697 R-SCE-429961 https://reactome.org/PathwayBrowser/#/R-SCE-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Saccharomyces cerevisiae 33697 R-SCE-450400 https://reactome.org/PathwayBrowser/#/R-SCE-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Saccharomyces cerevisiae 33697 R-SCE-450431 https://reactome.org/PathwayBrowser/#/R-SCE-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Saccharomyces cerevisiae 33697 R-SCE-450488 https://reactome.org/PathwayBrowser/#/R-SCE-450488 BRF1 Complex recruits RNA degradation activities IEA Saccharomyces cerevisiae 33697 R-SCE-450490 https://reactome.org/PathwayBrowser/#/R-SCE-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Saccharomyces cerevisiae 33697 R-SCE-450517 https://reactome.org/PathwayBrowser/#/R-SCE-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Saccharomyces cerevisiae 33697 R-SCE-68913 https://reactome.org/PathwayBrowser/#/R-SCE-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Saccharomyces cerevisiae 33697 R-SCE-68950 https://reactome.org/PathwayBrowser/#/R-SCE-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Saccharomyces cerevisiae 33697 R-SCE-69053 https://reactome.org/PathwayBrowser/#/R-SCE-69053 RFC binding displaces Pol Alpha IEA Saccharomyces cerevisiae 33697 R-SCE-69063 https://reactome.org/PathwayBrowser/#/R-SCE-69063 Loading of PCNA - Sliding Clamp Formation IEA Saccharomyces cerevisiae 33697 R-SCE-69068 https://reactome.org/PathwayBrowser/#/R-SCE-69068 RFC dissociates after sliding clamp formation IEA Saccharomyces cerevisiae 33697 R-SCE-69127 https://reactome.org/PathwayBrowser/#/R-SCE-69127 Formation of the Flap Intermediate IEA Saccharomyces cerevisiae 33697 R-SCE-69142 https://reactome.org/PathwayBrowser/#/R-SCE-69142 Recruitment of Dna2 endonuclease IEA Saccharomyces cerevisiae 33697 R-SCE-69152 https://reactome.org/PathwayBrowser/#/R-SCE-69152 Removal of remaining Flap IEA Saccharomyces cerevisiae 33697 R-SCE-74986 https://reactome.org/PathwayBrowser/#/R-SCE-74986 Elongation of pre-rRNA transcript IEA Saccharomyces cerevisiae 33697 R-SCE-75097 https://reactome.org/PathwayBrowser/#/R-SCE-75097 Transport of the export-competent mRNP complex through the NPC IEA Saccharomyces cerevisiae 33697 R-SCE-77077 https://reactome.org/PathwayBrowser/#/R-SCE-77077 Capping complex formation IEA Saccharomyces cerevisiae 33697 R-SCE-77078 https://reactome.org/PathwayBrowser/#/R-SCE-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Saccharomyces cerevisiae 33697 R-SCE-77081 https://reactome.org/PathwayBrowser/#/R-SCE-77081 Formation of the CE:GMP intermediate complex IEA Saccharomyces cerevisiae 33697 R-SCE-77083 https://reactome.org/PathwayBrowser/#/R-SCE-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Saccharomyces cerevisiae 33697 R-SCE-77085 https://reactome.org/PathwayBrowser/#/R-SCE-77085 Dissociation of transcript with 5'-GMP from GT IEA Saccharomyces cerevisiae 33697 R-SCE-77090 https://reactome.org/PathwayBrowser/#/R-SCE-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Saccharomyces cerevisiae 33697 R-SCE-77095 https://reactome.org/PathwayBrowser/#/R-SCE-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Saccharomyces cerevisiae 33697 R-SCE-77589 https://reactome.org/PathwayBrowser/#/R-SCE-77589 Recognition of AAUAAA sequence by CPSF IEA Saccharomyces cerevisiae 33697 R-SCE-927789 https://reactome.org/PathwayBrowser/#/R-SCE-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Saccharomyces cerevisiae 33697 R-SCE-927830 https://reactome.org/PathwayBrowser/#/R-SCE-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex IEA Saccharomyces cerevisiae 33697 R-SCE-927836 https://reactome.org/PathwayBrowser/#/R-SCE-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Saccharomyces cerevisiae 33697 R-SCE-927889 https://reactome.org/PathwayBrowser/#/R-SCE-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Saccharomyces cerevisiae 33697 R-SPO-112383 https://reactome.org/PathwayBrowser/#/R-SPO-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Schizosaccharomyces pombe 33697 R-SPO-113407 https://reactome.org/PathwayBrowser/#/R-SPO-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Schizosaccharomyces pombe 33697 R-SPO-113409 https://reactome.org/PathwayBrowser/#/R-SPO-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Schizosaccharomyces pombe 33697 R-SPO-113504 https://reactome.org/PathwayBrowser/#/R-SPO-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Schizosaccharomyces pombe 33697 R-SPO-158441 https://reactome.org/PathwayBrowser/#/R-SPO-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Schizosaccharomyces pombe 33697 R-SPO-158447 https://reactome.org/PathwayBrowser/#/R-SPO-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Schizosaccharomyces pombe 33697 R-SPO-158481 https://reactome.org/PathwayBrowser/#/R-SPO-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Schizosaccharomyces pombe 33697 R-SPO-158484 https://reactome.org/PathwayBrowser/#/R-SPO-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Schizosaccharomyces pombe 33697 R-SPO-426520 https://reactome.org/PathwayBrowser/#/R-SPO-426520 Endonucleolytic RISC hydrolyzes target RNAs IEA Schizosaccharomyces pombe 33697 R-SPO-429961 https://reactome.org/PathwayBrowser/#/R-SPO-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Schizosaccharomyces pombe 33697 R-SPO-450400 https://reactome.org/PathwayBrowser/#/R-SPO-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Schizosaccharomyces pombe 33697 R-SPO-450490 https://reactome.org/PathwayBrowser/#/R-SPO-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Schizosaccharomyces pombe 33697 R-SPO-450517 https://reactome.org/PathwayBrowser/#/R-SPO-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Schizosaccharomyces pombe 33697 R-SPO-68913 https://reactome.org/PathwayBrowser/#/R-SPO-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Schizosaccharomyces pombe 33697 R-SPO-68950 https://reactome.org/PathwayBrowser/#/R-SPO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Schizosaccharomyces pombe 33697 R-SPO-69053 https://reactome.org/PathwayBrowser/#/R-SPO-69053 RFC binding displaces Pol Alpha IEA Schizosaccharomyces pombe 33697 R-SPO-69063 https://reactome.org/PathwayBrowser/#/R-SPO-69063 Loading of PCNA - Sliding Clamp Formation IEA Schizosaccharomyces pombe 33697 R-SPO-69068 https://reactome.org/PathwayBrowser/#/R-SPO-69068 RFC dissociates after sliding clamp formation IEA Schizosaccharomyces pombe 33697 R-SPO-69074 https://reactome.org/PathwayBrowser/#/R-SPO-69074 Formation of Processive Complex IEA Schizosaccharomyces pombe 33697 R-SPO-69116 https://reactome.org/PathwayBrowser/#/R-SPO-69116 Formation of Okazaki fragments IEA Schizosaccharomyces pombe 33697 R-SPO-69127 https://reactome.org/PathwayBrowser/#/R-SPO-69127 Formation of the Flap Intermediate IEA Schizosaccharomyces pombe 33697 R-SPO-69140 https://reactome.org/PathwayBrowser/#/R-SPO-69140 RPA binds to the Flap IEA Schizosaccharomyces pombe 33697 R-SPO-69142 https://reactome.org/PathwayBrowser/#/R-SPO-69142 Recruitment of Dna2 endonuclease IEA Schizosaccharomyces pombe 33697 R-SPO-69144 https://reactome.org/PathwayBrowser/#/R-SPO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Schizosaccharomyces pombe 33697 R-SPO-69152 https://reactome.org/PathwayBrowser/#/R-SPO-69152 Removal of remaining Flap IEA Schizosaccharomyces pombe 33697 R-SPO-74986 https://reactome.org/PathwayBrowser/#/R-SPO-74986 Elongation of pre-rRNA transcript IEA Schizosaccharomyces pombe 33697 R-SPO-75097 https://reactome.org/PathwayBrowser/#/R-SPO-75097 Transport of the export-competent mRNP complex through the NPC IEA Schizosaccharomyces pombe 33697 R-SPO-77077 https://reactome.org/PathwayBrowser/#/R-SPO-77077 Capping complex formation IEA Schizosaccharomyces pombe 33697 R-SPO-77078 https://reactome.org/PathwayBrowser/#/R-SPO-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Schizosaccharomyces pombe 33697 R-SPO-77081 https://reactome.org/PathwayBrowser/#/R-SPO-77081 Formation of the CE:GMP intermediate complex IEA Schizosaccharomyces pombe 33697 R-SPO-77083 https://reactome.org/PathwayBrowser/#/R-SPO-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Schizosaccharomyces pombe 33697 R-SPO-77085 https://reactome.org/PathwayBrowser/#/R-SPO-77085 Dissociation of transcript with 5'-GMP from GT IEA Schizosaccharomyces pombe 33697 R-SPO-77090 https://reactome.org/PathwayBrowser/#/R-SPO-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Schizosaccharomyces pombe 33697 R-SPO-77095 https://reactome.org/PathwayBrowser/#/R-SPO-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Schizosaccharomyces pombe 33697 R-SPO-77589 https://reactome.org/PathwayBrowser/#/R-SPO-77589 Recognition of AAUAAA sequence by CPSF IEA Schizosaccharomyces pombe 33697 R-SPO-77594 https://reactome.org/PathwayBrowser/#/R-SPO-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Schizosaccharomyces pombe 33697 R-SPO-9023909 https://reactome.org/PathwayBrowser/#/R-SPO-9023909 C3PO hydrolyzes cleaved passenger strand IEA Schizosaccharomyces pombe 33697 R-SPO-927789 https://reactome.org/PathwayBrowser/#/R-SPO-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Schizosaccharomyces pombe 33697 R-SPO-927836 https://reactome.org/PathwayBrowser/#/R-SPO-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Schizosaccharomyces pombe 33697 R-SPO-927889 https://reactome.org/PathwayBrowser/#/R-SPO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Schizosaccharomyces pombe 33697 R-SSC-112381 https://reactome.org/PathwayBrowser/#/R-SSC-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Sus scrofa 33697 R-SSC-112383 https://reactome.org/PathwayBrowser/#/R-SSC-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Sus scrofa 33697 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa 33697 R-SSC-112392 https://reactome.org/PathwayBrowser/#/R-SSC-112392 Resumption of elongation after recovery from pausing IEA Sus scrofa 33697 R-SSC-112395 https://reactome.org/PathwayBrowser/#/R-SSC-112395 Abortive termination of elongation after arrest IEA Sus scrofa 33697 R-SSC-112396 https://reactome.org/PathwayBrowser/#/R-SSC-112396 Separation of elongating transcript from template IEA Sus scrofa 33697 R-SSC-113402 https://reactome.org/PathwayBrowser/#/R-SSC-113402 Formation of DSIF:NELF:early elongation complex IEA Sus scrofa 33697 R-SSC-113407 https://reactome.org/PathwayBrowser/#/R-SSC-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Sus scrofa 33697 R-SSC-113409 https://reactome.org/PathwayBrowser/#/R-SSC-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Sus scrofa 33697 R-SSC-113411 https://reactome.org/PathwayBrowser/#/R-SSC-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Sus scrofa 33697 R-SSC-113412 https://reactome.org/PathwayBrowser/#/R-SSC-113412 Pol II elongation complex moves on the template as transcript elongates IEA Sus scrofa 33697 R-SSC-113413 https://reactome.org/PathwayBrowser/#/R-SSC-113413 TFIIS-mediated recovery of elongation from arrest IEA Sus scrofa 33697 R-SSC-113414 https://reactome.org/PathwayBrowser/#/R-SSC-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Sus scrofa 33697 R-SSC-113429 https://reactome.org/PathwayBrowser/#/R-SSC-113429 Elongating transcript encounters a lesion in the template IEA Sus scrofa 33697 R-SSC-113504 https://reactome.org/PathwayBrowser/#/R-SSC-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Sus scrofa 33697 R-SSC-158441 https://reactome.org/PathwayBrowser/#/R-SSC-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa 33697 R-SSC-158447 https://reactome.org/PathwayBrowser/#/R-SSC-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Sus scrofa 33697 R-SSC-158481 https://reactome.org/PathwayBrowser/#/R-SSC-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa 33697 R-SSC-158484 https://reactome.org/PathwayBrowser/#/R-SSC-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Sus scrofa 33697 R-SSC-159046 https://reactome.org/PathwayBrowser/#/R-SSC-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Sus scrofa 33697 R-SSC-159050 https://reactome.org/PathwayBrowser/#/R-SSC-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Sus scrofa 33697 R-SSC-159101 https://reactome.org/PathwayBrowser/#/R-SSC-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Sus scrofa 33697 R-SSC-174425 https://reactome.org/PathwayBrowser/#/R-SSC-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Sus scrofa 33697 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa 33697 R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa 33697 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa 33697 R-SSC-174444 https://reactome.org/PathwayBrowser/#/R-SSC-174444 Formation of C-strand Okazaki fragments IEA Sus scrofa 33697 R-SSC-174447 https://reactome.org/PathwayBrowser/#/R-SSC-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Sus scrofa 33697 R-SSC-174448 https://reactome.org/PathwayBrowser/#/R-SSC-174448 Formation of Processive Complex on the C-strand of the telomere IEA Sus scrofa 33697 R-SSC-174452 https://reactome.org/PathwayBrowser/#/R-SSC-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Sus scrofa 33697 R-SSC-2106615 https://reactome.org/PathwayBrowser/#/R-SSC-2106615 Removal of siRNA passenger strand IEA Sus scrofa 33697 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 33697 R-SSC-426489 https://reactome.org/PathwayBrowser/#/R-SSC-426489 RISC binds inexactly matching target RNAs IEA Sus scrofa 33697 R-SSC-426520 https://reactome.org/PathwayBrowser/#/R-SSC-426520 Endonucleolytic RISC hydrolyzes target RNAs IEA Sus scrofa 33697 R-SSC-426522 https://reactome.org/PathwayBrowser/#/R-SSC-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Sus scrofa 33697 R-SSC-429961 https://reactome.org/PathwayBrowser/#/R-SSC-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Sus scrofa 33697 R-SSC-450387 https://reactome.org/PathwayBrowser/#/R-SSC-450387 HuR binds the CRM1 nuclear export machinery IEA Sus scrofa 33697 R-SSC-450394 https://reactome.org/PathwayBrowser/#/R-SSC-450394 p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta IEA Sus scrofa 33697 R-SSC-450400 https://reactome.org/PathwayBrowser/#/R-SSC-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Sus scrofa 33697 R-SSC-450406 https://reactome.org/PathwayBrowser/#/R-SSC-450406 p-S92,203-BRF1 binds 14-3-3 IEA Sus scrofa 33697 R-SSC-450422 https://reactome.org/PathwayBrowser/#/R-SSC-450422 KSRP recruits RNA degradation activities IEA Sus scrofa 33697 R-SSC-450431 https://reactome.org/PathwayBrowser/#/R-SSC-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Sus scrofa 33697 R-SSC-450434 https://reactome.org/PathwayBrowser/#/R-SSC-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA IEA Sus scrofa 33697 R-SSC-450463 https://reactome.org/PathwayBrowser/#/R-SSC-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Sus scrofa 33697 R-SSC-450466 https://reactome.org/PathwayBrowser/#/R-SSC-450466 AUF1:mRNA complex is destroyed IEA Sus scrofa 33697 R-SSC-450474 https://reactome.org/PathwayBrowser/#/R-SSC-450474 MK2 phosphorylates BRF1 IEA Sus scrofa 33697 R-SSC-450488 https://reactome.org/PathwayBrowser/#/R-SSC-450488 BRF1 Complex recruits RNA degradation activities IEA Sus scrofa 33697 R-SSC-450494 https://reactome.org/PathwayBrowser/#/R-SSC-450494 HuR binds mRNAs in the nucleus IEA Sus scrofa 33697 R-SSC-450517 https://reactome.org/PathwayBrowser/#/R-SSC-450517 Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA IEA Sus scrofa 33697 R-SSC-450551 https://reactome.org/PathwayBrowser/#/R-SSC-450551 AUF1 binds translation and heat shock proteins IEA Sus scrofa 33697 R-SSC-450580 https://reactome.org/PathwayBrowser/#/R-SSC-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Sus scrofa 33697 R-SSC-450592 https://reactome.org/PathwayBrowser/#/R-SSC-450592 KSRP binds AU-rich element in 3' UTR of mRNA IEA Sus scrofa 33697 R-SSC-450595 https://reactome.org/PathwayBrowser/#/R-SSC-450595 HuR:mRNA complex translocates from the nucleus to the cytosol IEA Sus scrofa 33697 R-SSC-482788 https://reactome.org/PathwayBrowser/#/R-SSC-482788 p-S54,92,203-BRF1 binds 14-3-3 IEA Sus scrofa 33697 R-SSC-517674 https://reactome.org/PathwayBrowser/#/R-SSC-517674 p-S158,221-HuR binds mRNA IEA Sus scrofa 33697 R-SSC-517705 https://reactome.org/PathwayBrowser/#/R-SSC-517705 p-S318,221-HuR binds mRNA IEA Sus scrofa 33697 R-SSC-68913 https://reactome.org/PathwayBrowser/#/R-SSC-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Sus scrofa 33697 R-SSC-68950 https://reactome.org/PathwayBrowser/#/R-SSC-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Sus scrofa 33697 R-SSC-69053 https://reactome.org/PathwayBrowser/#/R-SSC-69053 RFC binding displaces Pol Alpha IEA Sus scrofa 33697 R-SSC-69063 https://reactome.org/PathwayBrowser/#/R-SSC-69063 Loading of PCNA - Sliding Clamp Formation IEA Sus scrofa 33697 R-SSC-69068 https://reactome.org/PathwayBrowser/#/R-SSC-69068 RFC dissociates after sliding clamp formation IEA Sus scrofa 33697 R-SSC-69074 https://reactome.org/PathwayBrowser/#/R-SSC-69074 Formation of Processive Complex IEA Sus scrofa 33697 R-SSC-69116 https://reactome.org/PathwayBrowser/#/R-SSC-69116 Formation of Okazaki fragments IEA Sus scrofa 33697 R-SSC-69127 https://reactome.org/PathwayBrowser/#/R-SSC-69127 Formation of the Flap Intermediate IEA Sus scrofa 33697 R-SSC-69140 https://reactome.org/PathwayBrowser/#/R-SSC-69140 RPA binds to the Flap IEA Sus scrofa 33697 R-SSC-69142 https://reactome.org/PathwayBrowser/#/R-SSC-69142 Recruitment of Dna2 endonuclease IEA Sus scrofa 33697 R-SSC-69144 https://reactome.org/PathwayBrowser/#/R-SSC-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Sus scrofa 33697 R-SSC-69152 https://reactome.org/PathwayBrowser/#/R-SSC-69152 Removal of remaining Flap IEA Sus scrofa 33697 R-SSC-72095 https://reactome.org/PathwayBrowser/#/R-SSC-72095 Internal Methylation of mRNA IEA Sus scrofa 33697 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa 33697 R-SSC-72185 https://reactome.org/PathwayBrowser/#/R-SSC-72185 mRNA polyadenylation IEA Sus scrofa 33697 R-SSC-74986 https://reactome.org/PathwayBrowser/#/R-SSC-74986 Elongation of pre-rRNA transcript IEA Sus scrofa 33697 R-SSC-75083 https://reactome.org/PathwayBrowser/#/R-SSC-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Sus scrofa 33697 R-SSC-75097 https://reactome.org/PathwayBrowser/#/R-SSC-75097 Transport of the export-competent mRNP complex through the NPC IEA Sus scrofa 33697 R-SSC-77077 https://reactome.org/PathwayBrowser/#/R-SSC-77077 Capping complex formation IEA Sus scrofa 33697 R-SSC-77078 https://reactome.org/PathwayBrowser/#/R-SSC-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Sus scrofa 33697 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa 33697 R-SSC-77083 https://reactome.org/PathwayBrowser/#/R-SSC-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Sus scrofa 33697 R-SSC-77085 https://reactome.org/PathwayBrowser/#/R-SSC-77085 Dissociation of transcript with 5'-GMP from GT IEA Sus scrofa 33697 R-SSC-77090 https://reactome.org/PathwayBrowser/#/R-SSC-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Sus scrofa 33697 R-SSC-77095 https://reactome.org/PathwayBrowser/#/R-SSC-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Sus scrofa 33697 R-SSC-77589 https://reactome.org/PathwayBrowser/#/R-SSC-77589 Recognition of AAUAAA sequence by CPSF IEA Sus scrofa 33697 R-SSC-77590 https://reactome.org/PathwayBrowser/#/R-SSC-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Sus scrofa 33697 R-SSC-77591 https://reactome.org/PathwayBrowser/#/R-SSC-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Sus scrofa 33697 R-SSC-77592 https://reactome.org/PathwayBrowser/#/R-SSC-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Sus scrofa 33697 R-SSC-77593 https://reactome.org/PathwayBrowser/#/R-SSC-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Sus scrofa 33697 R-SSC-77594 https://reactome.org/PathwayBrowser/#/R-SSC-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Sus scrofa 33697 R-SSC-77608 https://reactome.org/PathwayBrowser/#/R-SSC-77608 Binding of A1CF to stem-looped RNA IEA Sus scrofa 33697 R-SSC-77609 https://reactome.org/PathwayBrowser/#/R-SSC-77609 Binding of APOBEC-1 to form editosome IEA Sus scrofa 33697 R-SSC-77614 https://reactome.org/PathwayBrowser/#/R-SSC-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Sus scrofa 33697 R-SSC-77615 https://reactome.org/PathwayBrowser/#/R-SSC-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Sus scrofa 33697 R-SSC-83677 https://reactome.org/PathwayBrowser/#/R-SSC-83677 C4 deamination of cytidine IEA Sus scrofa 33697 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa 33697 R-SSC-9009936 https://reactome.org/PathwayBrowser/#/R-SSC-9009936 RNASEL cleaves cellular ssRNA IEA Sus scrofa 33697 R-SSC-9023909 https://reactome.org/PathwayBrowser/#/R-SSC-9023909 C3PO hydrolyzes cleaved passenger strand IEA Sus scrofa 33697 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa 33697 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa 33697 R-SSC-927830 https://reactome.org/PathwayBrowser/#/R-SSC-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex IEA Sus scrofa 33697 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa 33697 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa 33697 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa 33697 R-SSC-9833777 https://reactome.org/PathwayBrowser/#/R-SSC-9833777 PKR binds activating host RNA IEA Sus scrofa 33697 R-XTR-112381 https://reactome.org/PathwayBrowser/#/R-XTR-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Xenopus tropicalis 33697 R-XTR-112385 https://reactome.org/PathwayBrowser/#/R-XTR-112385 Addition of nucleotides leads to transcript elongation IEA Xenopus tropicalis 33697 R-XTR-112392 https://reactome.org/PathwayBrowser/#/R-XTR-112392 Resumption of elongation after recovery from pausing IEA Xenopus tropicalis 33697 R-XTR-112395 https://reactome.org/PathwayBrowser/#/R-XTR-112395 Abortive termination of elongation after arrest IEA Xenopus tropicalis 33697 R-XTR-112396 https://reactome.org/PathwayBrowser/#/R-XTR-112396 Separation of elongating transcript from template IEA Xenopus tropicalis 33697 R-XTR-113402 https://reactome.org/PathwayBrowser/#/R-XTR-113402 Formation of DSIF:NELF:early elongation complex IEA Xenopus tropicalis 33697 R-XTR-113409 https://reactome.org/PathwayBrowser/#/R-XTR-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Xenopus tropicalis 33697 R-XTR-113411 https://reactome.org/PathwayBrowser/#/R-XTR-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Xenopus tropicalis 33697 R-XTR-113412 https://reactome.org/PathwayBrowser/#/R-XTR-113412 Pol II elongation complex moves on the template as transcript elongates IEA Xenopus tropicalis 33697 R-XTR-113413 https://reactome.org/PathwayBrowser/#/R-XTR-113413 TFIIS-mediated recovery of elongation from arrest IEA Xenopus tropicalis 33697 R-XTR-113414 https://reactome.org/PathwayBrowser/#/R-XTR-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Xenopus tropicalis 33697 R-XTR-174439 https://reactome.org/PathwayBrowser/#/R-XTR-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Xenopus tropicalis 33697 R-XTR-174447 https://reactome.org/PathwayBrowser/#/R-XTR-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Xenopus tropicalis 33697 R-XTR-2106615 https://reactome.org/PathwayBrowser/#/R-XTR-2106615 Removal of siRNA passenger strand IEA Xenopus tropicalis 33697 R-XTR-426489 https://reactome.org/PathwayBrowser/#/R-XTR-426489 RISC binds inexactly matching target RNAs IEA Xenopus tropicalis 33697 R-XTR-426520 https://reactome.org/PathwayBrowser/#/R-XTR-426520 Endonucleolytic RISC hydrolyzes target RNAs IEA Xenopus tropicalis 33697 R-XTR-426522 https://reactome.org/PathwayBrowser/#/R-XTR-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Xenopus tropicalis 33697 R-XTR-429961 https://reactome.org/PathwayBrowser/#/R-XTR-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Xenopus tropicalis 33697 R-XTR-450394 https://reactome.org/PathwayBrowser/#/R-XTR-450394 p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta IEA Xenopus tropicalis 33697 R-XTR-450400 https://reactome.org/PathwayBrowser/#/R-XTR-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Xenopus tropicalis 33697 R-XTR-450406 https://reactome.org/PathwayBrowser/#/R-XTR-450406 p-S92,203-BRF1 binds 14-3-3 IEA Xenopus tropicalis 33697 R-XTR-450422 https://reactome.org/PathwayBrowser/#/R-XTR-450422 KSRP recruits RNA degradation activities IEA Xenopus tropicalis 33697 R-XTR-450431 https://reactome.org/PathwayBrowser/#/R-XTR-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Xenopus tropicalis 33697 R-XTR-450434 https://reactome.org/PathwayBrowser/#/R-XTR-450434 AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA IEA Xenopus tropicalis 33697 R-XTR-450488 https://reactome.org/PathwayBrowser/#/R-XTR-450488 BRF1 Complex recruits RNA degradation activities IEA Xenopus tropicalis 33697 R-XTR-450494 https://reactome.org/PathwayBrowser/#/R-XTR-450494 HuR binds mRNAs in the nucleus IEA Xenopus tropicalis 33697 R-XTR-450580 https://reactome.org/PathwayBrowser/#/R-XTR-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Xenopus tropicalis 33697 R-XTR-450592 https://reactome.org/PathwayBrowser/#/R-XTR-450592 KSRP binds AU-rich element in 3' UTR of mRNA IEA Xenopus tropicalis 33697 R-XTR-482788 https://reactome.org/PathwayBrowser/#/R-XTR-482788 p-S54,92,203-BRF1 binds 14-3-3 IEA Xenopus tropicalis 33697 R-XTR-517674 https://reactome.org/PathwayBrowser/#/R-XTR-517674 p-S158,221-HuR binds mRNA IEA Xenopus tropicalis 33697 R-XTR-517705 https://reactome.org/PathwayBrowser/#/R-XTR-517705 p-S318,221-HuR binds mRNA IEA Xenopus tropicalis 33697 R-XTR-72095 https://reactome.org/PathwayBrowser/#/R-XTR-72095 Internal Methylation of mRNA IEA Xenopus tropicalis 33697 R-XTR-74986 https://reactome.org/PathwayBrowser/#/R-XTR-74986 Elongation of pre-rRNA transcript IEA Xenopus tropicalis 33697 R-XTR-75083 https://reactome.org/PathwayBrowser/#/R-XTR-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Xenopus tropicalis 33697 R-XTR-77077 https://reactome.org/PathwayBrowser/#/R-XTR-77077 Capping complex formation IEA Xenopus tropicalis 33697 R-XTR-77078 https://reactome.org/PathwayBrowser/#/R-XTR-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Xenopus tropicalis 33697 R-XTR-77081 https://reactome.org/PathwayBrowser/#/R-XTR-77081 Formation of the CE:GMP intermediate complex IEA Xenopus tropicalis 33697 R-XTR-77083 https://reactome.org/PathwayBrowser/#/R-XTR-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Xenopus tropicalis 33697 R-XTR-77085 https://reactome.org/PathwayBrowser/#/R-XTR-77085 Dissociation of transcript with 5'-GMP from GT IEA Xenopus tropicalis 33697 R-XTR-77095 https://reactome.org/PathwayBrowser/#/R-XTR-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Xenopus tropicalis 33697 R-XTR-77608 https://reactome.org/PathwayBrowser/#/R-XTR-77608 Binding of A1CF to stem-looped RNA IEA Xenopus tropicalis 33697 R-XTR-77615 https://reactome.org/PathwayBrowser/#/R-XTR-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Xenopus tropicalis 33697 R-XTR-9009936 https://reactome.org/PathwayBrowser/#/R-XTR-9009936 RNASEL cleaves cellular ssRNA IEA Xenopus tropicalis 33697 R-XTR-9023909 https://reactome.org/PathwayBrowser/#/R-XTR-9023909 C3PO hydrolyzes cleaved passenger strand IEA Xenopus tropicalis 33697 R-XTR-927789 https://reactome.org/PathwayBrowser/#/R-XTR-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Xenopus tropicalis 33697 R-XTR-927813 https://reactome.org/PathwayBrowser/#/R-XTR-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Xenopus tropicalis 33697 R-XTR-927830 https://reactome.org/PathwayBrowser/#/R-XTR-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex IEA Xenopus tropicalis 33697 R-XTR-927832 https://reactome.org/PathwayBrowser/#/R-XTR-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Xenopus tropicalis 33697 R-XTR-927836 https://reactome.org/PathwayBrowser/#/R-XTR-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Xenopus tropicalis 33697 R-XTR-927889 https://reactome.org/PathwayBrowser/#/R-XTR-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Xenopus tropicalis 33697 R-XTR-9833777 https://reactome.org/PathwayBrowser/#/R-XTR-9833777 PKR binds activating host RNA IEA Xenopus tropicalis 33699 R-BTA-111437 https://reactome.org/PathwayBrowser/#/R-BTA-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Bos taurus 33699 R-BTA-111438 https://reactome.org/PathwayBrowser/#/R-BTA-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Bos taurus 33699 R-BTA-111439 https://reactome.org/PathwayBrowser/#/R-BTA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Bos taurus 33699 R-BTA-158481 https://reactome.org/PathwayBrowser/#/R-BTA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Bos taurus 33699 R-BTA-159046 https://reactome.org/PathwayBrowser/#/R-BTA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Bos taurus 33699 R-BTA-429860 https://reactome.org/PathwayBrowser/#/R-BTA-429860 DCP1-DCP2 complex decaps mRNA IEA Bos taurus 33699 R-BTA-429955 https://reactome.org/PathwayBrowser/#/R-BTA-429955 CCR4-NOT complex deadenylates mRNA IEA Bos taurus 33699 R-BTA-429961 https://reactome.org/PathwayBrowser/#/R-BTA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Bos taurus 33699 R-BTA-429978 https://reactome.org/PathwayBrowser/#/R-BTA-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Bos taurus 33699 R-BTA-429992 https://reactome.org/PathwayBrowser/#/R-BTA-429992 PARN deadenylates mRNA IEA Bos taurus 33699 R-BTA-430021 https://reactome.org/PathwayBrowser/#/R-BTA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Bos taurus 33699 R-BTA-430028 https://reactome.org/PathwayBrowser/#/R-BTA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Bos taurus 33699 R-BTA-5419261 https://reactome.org/PathwayBrowser/#/R-BTA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Bos taurus 33699 R-BTA-5419264 https://reactome.org/PathwayBrowser/#/R-BTA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Bos taurus 33699 R-BTA-5419271 https://reactome.org/PathwayBrowser/#/R-BTA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Bos taurus 33699 R-BTA-5419281 https://reactome.org/PathwayBrowser/#/R-BTA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Bos taurus 33699 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 33699 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 33699 R-BTA-5432421 https://reactome.org/PathwayBrowser/#/R-BTA-5432421 39S subunit binds 28S subunit:mRNA:fMet-tRNA TAS Bos taurus 33699 R-BTA-5432422 https://reactome.org/PathwayBrowser/#/R-BTA-5432422 Translocation of 55S ribosome by 3 bases in the 3' direction TAS Bos taurus 33699 R-BTA-5432444 https://reactome.org/PathwayBrowser/#/R-BTA-5432444 Peptide transfer from P-site to A-site (peptide bond formation) TAS Bos taurus 33699 R-BTA-5432463 https://reactome.org/PathwayBrowser/#/R-BTA-5432463 28S subunit binds MITF2:GTP, mRNA, and formylMet-tRNA TAS Bos taurus 33699 R-BTA-77584 https://reactome.org/PathwayBrowser/#/R-BTA-77584 Binding of SLBP to Replication-Dependent Histone Pre-mRNA IEA Bos taurus 33699 R-BTA-77585 https://reactome.org/PathwayBrowser/#/R-BTA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Bos taurus 33699 R-BTA-77586 https://reactome.org/PathwayBrowser/#/R-BTA-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Bos taurus 33699 R-BTA-77587 https://reactome.org/PathwayBrowser/#/R-BTA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Bos taurus 33699 R-CEL-111437 https://reactome.org/PathwayBrowser/#/R-CEL-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Caenorhabditis elegans 33699 R-CEL-111438 https://reactome.org/PathwayBrowser/#/R-CEL-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Caenorhabditis elegans 33699 R-CEL-429860 https://reactome.org/PathwayBrowser/#/R-CEL-429860 DCP1-DCP2 complex decaps mRNA IEA Caenorhabditis elegans 33699 R-CEL-429961 https://reactome.org/PathwayBrowser/#/R-CEL-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Caenorhabditis elegans 33699 R-CEL-429978 https://reactome.org/PathwayBrowser/#/R-CEL-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Caenorhabditis elegans 33699 R-CEL-430028 https://reactome.org/PathwayBrowser/#/R-CEL-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Caenorhabditis elegans 33699 R-CEL-5419261 https://reactome.org/PathwayBrowser/#/R-CEL-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Caenorhabditis elegans 33699 R-CEL-5419264 https://reactome.org/PathwayBrowser/#/R-CEL-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Caenorhabditis elegans 33699 R-CEL-5419271 https://reactome.org/PathwayBrowser/#/R-CEL-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Caenorhabditis elegans 33699 R-CEL-5419281 https://reactome.org/PathwayBrowser/#/R-CEL-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Caenorhabditis elegans 33699 R-CEL-77584 https://reactome.org/PathwayBrowser/#/R-CEL-77584 Binding of SLBP to Replication-Dependent Histone Pre-mRNA IEA Caenorhabditis elegans 33699 R-CEL-77585 https://reactome.org/PathwayBrowser/#/R-CEL-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Caenorhabditis elegans 33699 R-CEL-77586 https://reactome.org/PathwayBrowser/#/R-CEL-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Caenorhabditis elegans 33699 R-CFA-111437 https://reactome.org/PathwayBrowser/#/R-CFA-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Canis familiaris 33699 R-CFA-111438 https://reactome.org/PathwayBrowser/#/R-CFA-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Canis familiaris 33699 R-CFA-111439 https://reactome.org/PathwayBrowser/#/R-CFA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Canis familiaris 33699 R-CFA-158481 https://reactome.org/PathwayBrowser/#/R-CFA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Canis familiaris 33699 R-CFA-159046 https://reactome.org/PathwayBrowser/#/R-CFA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Canis familiaris 33699 R-CFA-429860 https://reactome.org/PathwayBrowser/#/R-CFA-429860 DCP1-DCP2 complex decaps mRNA IEA Canis familiaris 33699 R-CFA-429955 https://reactome.org/PathwayBrowser/#/R-CFA-429955 CCR4-NOT complex deadenylates mRNA IEA Canis familiaris 33699 R-CFA-429961 https://reactome.org/PathwayBrowser/#/R-CFA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Canis familiaris 33699 R-CFA-429978 https://reactome.org/PathwayBrowser/#/R-CFA-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Canis familiaris 33699 R-CFA-429992 https://reactome.org/PathwayBrowser/#/R-CFA-429992 PARN deadenylates mRNA IEA Canis familiaris 33699 R-CFA-430021 https://reactome.org/PathwayBrowser/#/R-CFA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Canis familiaris 33699 R-CFA-430028 https://reactome.org/PathwayBrowser/#/R-CFA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Canis familiaris 33699 R-CFA-5419261 https://reactome.org/PathwayBrowser/#/R-CFA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Canis familiaris 33699 R-CFA-5419264 https://reactome.org/PathwayBrowser/#/R-CFA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Canis familiaris 33699 R-CFA-5419271 https://reactome.org/PathwayBrowser/#/R-CFA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Canis familiaris 33699 R-CFA-5419281 https://reactome.org/PathwayBrowser/#/R-CFA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Canis familiaris 33699 R-CFA-77584 https://reactome.org/PathwayBrowser/#/R-CFA-77584 Binding of SLBP to Replication-Dependent Histone Pre-mRNA IEA Canis familiaris 33699 R-CFA-77585 https://reactome.org/PathwayBrowser/#/R-CFA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Canis familiaris 33699 R-CFA-77586 https://reactome.org/PathwayBrowser/#/R-CFA-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Canis familiaris 33699 R-CFA-77587 https://reactome.org/PathwayBrowser/#/R-CFA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Canis familiaris 33699 R-DDI-111437 https://reactome.org/PathwayBrowser/#/R-DDI-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Dictyostelium discoideum 33699 R-DDI-111438 https://reactome.org/PathwayBrowser/#/R-DDI-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Dictyostelium discoideum 33699 R-DDI-429860 https://reactome.org/PathwayBrowser/#/R-DDI-429860 DCP1-DCP2 complex decaps mRNA IEA Dictyostelium discoideum 33699 R-DDI-429978 https://reactome.org/PathwayBrowser/#/R-DDI-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Dictyostelium discoideum 33699 R-DDI-430028 https://reactome.org/PathwayBrowser/#/R-DDI-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Dictyostelium discoideum 33699 R-DDI-77584 https://reactome.org/PathwayBrowser/#/R-DDI-77584 Binding of SLBP to Replication-Dependent Histone Pre-mRNA IEA Dictyostelium discoideum 33699 R-DDI-77585 https://reactome.org/PathwayBrowser/#/R-DDI-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Dictyostelium discoideum 33699 R-DDI-77586 https://reactome.org/PathwayBrowser/#/R-DDI-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Dictyostelium discoideum 33699 R-DME-111437 https://reactome.org/PathwayBrowser/#/R-DME-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Drosophila melanogaster 33699 R-DME-111438 https://reactome.org/PathwayBrowser/#/R-DME-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Drosophila melanogaster 33699 R-DME-111439 https://reactome.org/PathwayBrowser/#/R-DME-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Drosophila melanogaster 33699 R-DME-158481 https://reactome.org/PathwayBrowser/#/R-DME-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Drosophila melanogaster 33699 R-DME-159046 https://reactome.org/PathwayBrowser/#/R-DME-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Drosophila melanogaster 33699 R-DME-429860 https://reactome.org/PathwayBrowser/#/R-DME-429860 DCP1-DCP2 complex decaps mRNA IEA Drosophila melanogaster 33699 R-DME-429961 https://reactome.org/PathwayBrowser/#/R-DME-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Drosophila melanogaster 33699 R-DME-429978 https://reactome.org/PathwayBrowser/#/R-DME-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Drosophila melanogaster 33699 R-DME-430028 https://reactome.org/PathwayBrowser/#/R-DME-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Drosophila melanogaster 33699 R-DME-5419261 https://reactome.org/PathwayBrowser/#/R-DME-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Drosophila melanogaster 33699 R-DME-5419264 https://reactome.org/PathwayBrowser/#/R-DME-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Drosophila melanogaster 33699 R-DME-5419271 https://reactome.org/PathwayBrowser/#/R-DME-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Drosophila melanogaster 33699 R-DME-5419281 https://reactome.org/PathwayBrowser/#/R-DME-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Drosophila melanogaster 33699 R-DME-77584 https://reactome.org/PathwayBrowser/#/R-DME-77584 Binding of SLBP to Replication-Dependent Histone Pre-mRNA IEA Drosophila melanogaster 33699 R-DME-77585 https://reactome.org/PathwayBrowser/#/R-DME-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Drosophila melanogaster 33699 R-DME-77586 https://reactome.org/PathwayBrowser/#/R-DME-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Drosophila melanogaster 33699 R-DME-77587 https://reactome.org/PathwayBrowser/#/R-DME-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Drosophila melanogaster 33699 R-DRE-429860 https://reactome.org/PathwayBrowser/#/R-DRE-429860 DCP1-DCP2 complex decaps mRNA IEA Danio rerio 33699 R-DRE-429978 https://reactome.org/PathwayBrowser/#/R-DRE-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Danio rerio 33699 R-DRE-5419261 https://reactome.org/PathwayBrowser/#/R-DRE-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Danio rerio 33699 R-DRE-5419281 https://reactome.org/PathwayBrowser/#/R-DRE-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Danio rerio 33699 R-GGA-111437 https://reactome.org/PathwayBrowser/#/R-GGA-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Gallus gallus 33699 R-GGA-111438 https://reactome.org/PathwayBrowser/#/R-GGA-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Gallus gallus 33699 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus 33699 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus 33699 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus 33699 R-GGA-429860 https://reactome.org/PathwayBrowser/#/R-GGA-429860 DCP1-DCP2 complex decaps mRNA IEA Gallus gallus 33699 R-GGA-429955 https://reactome.org/PathwayBrowser/#/R-GGA-429955 CCR4-NOT complex deadenylates mRNA IEA Gallus gallus 33699 R-GGA-429961 https://reactome.org/PathwayBrowser/#/R-GGA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Gallus gallus 33699 R-GGA-429978 https://reactome.org/PathwayBrowser/#/R-GGA-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Gallus gallus 33699 R-GGA-429992 https://reactome.org/PathwayBrowser/#/R-GGA-429992 PARN deadenylates mRNA IEA Gallus gallus 33699 R-GGA-430021 https://reactome.org/PathwayBrowser/#/R-GGA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Gallus gallus 33699 R-GGA-430028 https://reactome.org/PathwayBrowser/#/R-GGA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Gallus gallus 33699 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus 33699 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus 33699 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Gallus gallus 33699 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus 33699 R-GGA-77584 https://reactome.org/PathwayBrowser/#/R-GGA-77584 Binding of SLBP to Replication-Dependent Histone Pre-mRNA IEA Gallus gallus 33699 R-GGA-77585 https://reactome.org/PathwayBrowser/#/R-GGA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Gallus gallus 33699 R-GGA-77586 https://reactome.org/PathwayBrowser/#/R-GGA-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Gallus gallus 33699 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus 33699 R-HSA-111437 https://reactome.org/PathwayBrowser/#/R-HSA-111437 Cleavage of the 3'-end of the Histone Pre-mRNA TAS Homo sapiens 33699 R-HSA-111438 https://reactome.org/PathwayBrowser/#/R-HSA-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA TAS Homo sapiens 33699 R-HSA-111439 https://reactome.org/PathwayBrowser/#/R-HSA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC TAS Homo sapiens 33699 R-HSA-141671 https://reactome.org/PathwayBrowser/#/R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex IEA Homo sapiens 33699 R-HSA-141673 https://reactome.org/PathwayBrowser/#/R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex IEA Homo sapiens 33699 R-HSA-141691 https://reactome.org/PathwayBrowser/#/R-HSA-141691 GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex IEA Homo sapiens 33699 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 33699 R-HSA-156912 https://reactome.org/PathwayBrowser/#/R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA IEA Homo sapiens 33699 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 33699 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 33699 R-HSA-157849 https://reactome.org/PathwayBrowser/#/R-HSA-157849 Formation of translation initiation complexes containing mRNA that does not circularize TAS Homo sapiens 33699 R-HSA-158481 https://reactome.org/PathwayBrowser/#/R-HSA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC TAS Homo sapiens 33699 R-HSA-159046 https://reactome.org/PathwayBrowser/#/R-HSA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC TAS Homo sapiens 33699 R-HSA-1678842 https://reactome.org/PathwayBrowser/#/R-HSA-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP TAS Homo sapiens 33699 R-HSA-1799326 https://reactome.org/PathwayBrowser/#/R-HSA-1799326 Signal-containing nascent peptide translocates to endoplasmic reticulum IEA Homo sapiens 33699 R-HSA-1799329 https://reactome.org/PathwayBrowser/#/R-HSA-1799329 Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein IEA Homo sapiens 33699 R-HSA-1799330 https://reactome.org/PathwayBrowser/#/R-HSA-1799330 The SRP receptor binds the SRP:nascent peptide:ribosome complex IEA Homo sapiens 33699 R-HSA-1799332 https://reactome.org/PathwayBrowser/#/R-HSA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) TAS Homo sapiens 33699 R-HSA-1799335 https://reactome.org/PathwayBrowser/#/R-HSA-1799335 Synthesis of nascent polypeptide containing signal sequence TAS Homo sapiens 33699 R-HSA-2408529 https://reactome.org/PathwayBrowser/#/R-HSA-2408529 Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome IEA Homo sapiens 33699 R-HSA-429845 https://reactome.org/PathwayBrowser/#/R-HSA-429845 5' to 3' exoribonuclease hydrolyzes decapped mRNA IEA Homo sapiens 33699 R-HSA-429860 https://reactome.org/PathwayBrowser/#/R-HSA-429860 DCP1-DCP2 complex decaps mRNA TAS Homo sapiens 33699 R-HSA-429955 https://reactome.org/PathwayBrowser/#/R-HSA-429955 CCR4-NOT complex deadenylates mRNA TAS Homo sapiens 33699 R-HSA-429961 https://reactome.org/PathwayBrowser/#/R-HSA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA TAS Homo sapiens 33699 R-HSA-429978 https://reactome.org/PathwayBrowser/#/R-HSA-429978 Lsm1-7 Complex binds deadenylated mRNA TAS Homo sapiens 33699 R-HSA-429992 https://reactome.org/PathwayBrowser/#/R-HSA-429992 PARN deadenylates mRNA TAS Homo sapiens 33699 R-HSA-430021 https://reactome.org/PathwayBrowser/#/R-HSA-430021 PAN2-PAN3 complex partially deadenylates mRNA TAS Homo sapiens 33699 R-HSA-430028 https://reactome.org/PathwayBrowser/#/R-HSA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion TAS Homo sapiens 33699 R-HSA-450595 https://reactome.org/PathwayBrowser/#/R-HSA-450595 HuR:mRNA complex translocates from the nucleus to the cytosol TAS Homo sapiens 33699 R-HSA-5333615 https://reactome.org/PathwayBrowser/#/R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC IEA Homo sapiens 33699 R-HSA-5389839 https://reactome.org/PathwayBrowser/#/R-HSA-5389839 39S subunit binds 28S subunit:mRNA:fMet-tRNA IEA Homo sapiens 33699 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 33699 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 33699 R-HSA-5389849 https://reactome.org/PathwayBrowser/#/R-HSA-5389849 28S subunit:MTIF3 binds MTIF2:GTP, mRNA, and formylMet-tRNA IEA Homo sapiens 33699 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 33699 R-HSA-5419261 https://reactome.org/PathwayBrowser/#/R-HSA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP TAS Homo sapiens 33699 R-HSA-5419264 https://reactome.org/PathwayBrowser/#/R-HSA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA TAS Homo sapiens 33699 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 33699 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 33699 R-HSA-5419279 https://reactome.org/PathwayBrowser/#/R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) IEA Homo sapiens 33699 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 33699 R-HSA-6782234 https://reactome.org/PathwayBrowser/#/R-HSA-6782234 Recovery of RNA synthesis after TC-NER TAS Homo sapiens 33699 R-HSA-6803523 https://reactome.org/PathwayBrowser/#/R-HSA-6803523 PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA TAS Homo sapiens 33699 R-HSA-6803527 https://reactome.org/PathwayBrowser/#/R-HSA-6803527 ESRP1 and 2 bind FGFR2 pre-mRNA to promote FGFR2b maturation and expression TAS Homo sapiens 33699 R-HSA-6803836 https://reactome.org/PathwayBrowser/#/R-HSA-6803836 FGFR2b-specific alternative splicing produces FGFR2b transcript TAS Homo sapiens 33699 R-HSA-6803838 https://reactome.org/PathwayBrowser/#/R-HSA-6803838 FGFR2c-specific alternative splicing produces FGFR2c transcript TAS Homo sapiens 33699 R-HSA-72619 https://reactome.org/PathwayBrowser/#/R-HSA-72619 eIF2:GTP is hydrolyzed, eIFs are released TAS Homo sapiens 33699 R-HSA-72621 https://reactome.org/PathwayBrowser/#/R-HSA-72621 Ribosomal scanning TAS Homo sapiens 33699 R-HSA-72635 https://reactome.org/PathwayBrowser/#/R-HSA-72635 eIF4F binds to mRNP TAS Homo sapiens 33699 R-HSA-72647 https://reactome.org/PathwayBrowser/#/R-HSA-72647 Cap-bound mRNA is activated by helicases TAS Homo sapiens 33699 R-HSA-72671 https://reactome.org/PathwayBrowser/#/R-HSA-72671 eIF5B:GTP is hydrolyzed and released TAS Homo sapiens 33699 R-HSA-72672 https://reactome.org/PathwayBrowser/#/R-HSA-72672 The 60S subunit joins the translation initiation complex TAS Homo sapiens 33699 R-HSA-72697 https://reactome.org/PathwayBrowser/#/R-HSA-72697 Start codon recognition TAS Homo sapiens 33699 R-HSA-75097 https://reactome.org/PathwayBrowser/#/R-HSA-75097 Transport of the export-competent mRNP complex through the NPC TAS Homo sapiens 33699 R-HSA-75098 https://reactome.org/PathwayBrowser/#/R-HSA-75098 mRNP complex dissociates from cytosolic face of NPC TAS Homo sapiens 33699 R-HSA-77584 https://reactome.org/PathwayBrowser/#/R-HSA-77584 Binding of SLBP to Replication-Dependent Histone Pre-mRNA TAS Homo sapiens 33699 R-HSA-77585 https://reactome.org/PathwayBrowser/#/R-HSA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA TAS Homo sapiens 33699 R-HSA-77586 https://reactome.org/PathwayBrowser/#/R-HSA-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA TAS Homo sapiens 33699 R-HSA-77587 https://reactome.org/PathwayBrowser/#/R-HSA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC TAS Homo sapiens 33699 R-HSA-8851710 https://reactome.org/PathwayBrowser/#/R-HSA-8851710 Aberrant alternative splicing yields a secreted FGFR2 IIIa TM disease variant IEA Homo sapiens 33699 R-HSA-8941312 https://reactome.org/PathwayBrowser/#/R-HSA-8941312 TUT4,TUT7 oligouridylate mRNA IEA Homo sapiens 33699 R-HSA-9014587 https://reactome.org/PathwayBrowser/#/R-HSA-9014587 Transcription of ROBO3.2 mRNA IEA Homo sapiens 33699 R-HSA-9014610 https://reactome.org/PathwayBrowser/#/R-HSA-9014610 Translation of ROBO3.2 mRNA initiates NMD IEA Homo sapiens 33699 R-HSA-9014652 https://reactome.org/PathwayBrowser/#/R-HSA-9014652 Translation of ROBO3.2 mRNA is negatively regulated by NMD IEA Homo sapiens 33699 R-HSA-9633005 https://reactome.org/PathwayBrowser/#/R-HSA-9633005 EIF2AK4 (GCN2) binds tRNA IEA Homo sapiens 33699 R-HSA-9633008 https://reactome.org/PathwayBrowser/#/R-HSA-9633008 p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1 IEA Homo sapiens 33699 R-HSA-9633742 https://reactome.org/PathwayBrowser/#/R-HSA-9633742 EIF2AK4 (GCN2) dimer autophosphorylates IEA Homo sapiens 33699 R-HSA-9634669 https://reactome.org/PathwayBrowser/#/R-HSA-9634669 IMPACT binds GCN1 IEA Homo sapiens 33699 R-HSA-9820887 https://reactome.org/PathwayBrowser/#/R-HSA-9820887 PABPN1 binds oligouridylated mRNA IEA Homo sapiens 33699 R-HSA-9820895 https://reactome.org/PathwayBrowser/#/R-HSA-9820895 DIS3L2 binds PABPN1 in PABPN1:uridylated mRNA complex IEA Homo sapiens 33699 R-HSA-9822437 https://reactome.org/PathwayBrowser/#/R-HSA-9822437 DIS3L2 hydrolyzes uridylated mRNA IEA Homo sapiens 33699 R-HSA-9833723 https://reactome.org/PathwayBrowser/#/R-HSA-9833723 PKR forms a dimer TAS Homo sapiens 33699 R-HSA-9839025 https://reactome.org/PathwayBrowser/#/R-HSA-9839025 HIV TAR RNA binds PKR TAS Homo sapiens 33699 R-MMU-111437 https://reactome.org/PathwayBrowser/#/R-MMU-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Mus musculus 33699 R-MMU-111438 https://reactome.org/PathwayBrowser/#/R-MMU-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Mus musculus 33699 R-MMU-111439 https://reactome.org/PathwayBrowser/#/R-MMU-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Mus musculus 33699 R-MMU-158481 https://reactome.org/PathwayBrowser/#/R-MMU-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Mus musculus 33699 R-MMU-159046 https://reactome.org/PathwayBrowser/#/R-MMU-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Mus musculus 33699 R-MMU-429860 https://reactome.org/PathwayBrowser/#/R-MMU-429860 DCP1-DCP2 complex decaps mRNA IEA Mus musculus 33699 R-MMU-429955 https://reactome.org/PathwayBrowser/#/R-MMU-429955 CCR4-NOT complex deadenylates mRNA IEA Mus musculus 33699 R-MMU-429961 https://reactome.org/PathwayBrowser/#/R-MMU-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Mus musculus 33699 R-MMU-429978 https://reactome.org/PathwayBrowser/#/R-MMU-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Mus musculus 33699 R-MMU-429992 https://reactome.org/PathwayBrowser/#/R-MMU-429992 PARN deadenylates mRNA IEA Mus musculus 33699 R-MMU-430021 https://reactome.org/PathwayBrowser/#/R-MMU-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Mus musculus 33699 R-MMU-430028 https://reactome.org/PathwayBrowser/#/R-MMU-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Mus musculus 33699 R-MMU-5419261 https://reactome.org/PathwayBrowser/#/R-MMU-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Mus musculus 33699 R-MMU-5419264 https://reactome.org/PathwayBrowser/#/R-MMU-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Mus musculus 33699 R-MMU-5419271 https://reactome.org/PathwayBrowser/#/R-MMU-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Mus musculus 33699 R-MMU-5419281 https://reactome.org/PathwayBrowser/#/R-MMU-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Mus musculus 33699 R-MMU-77584 https://reactome.org/PathwayBrowser/#/R-MMU-77584 Binding of SLBP to Replication-Dependent Histone Pre-mRNA IEA Mus musculus 33699 R-MMU-77585 https://reactome.org/PathwayBrowser/#/R-MMU-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Mus musculus 33699 R-MMU-77586 https://reactome.org/PathwayBrowser/#/R-MMU-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Mus musculus 33699 R-MMU-77587 https://reactome.org/PathwayBrowser/#/R-MMU-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Mus musculus 33699 R-MMU-9820839 https://reactome.org/PathwayBrowser/#/R-MMU-9820839 Dis3l2 binds Pabpn1 in Pabpn1:uridylated mRNA complex TAS Mus musculus 33699 R-MMU-9820880 https://reactome.org/PathwayBrowser/#/R-MMU-9820880 Pabpn1 binds oligouridylated mRNA TAS Mus musculus 33699 R-MMU-9820884 https://reactome.org/PathwayBrowser/#/R-MMU-9820884 Tut4,Tut7 oligouridylate mRNA TAS Mus musculus 33699 R-MMU-9822432 https://reactome.org/PathwayBrowser/#/R-MMU-9822432 Dis3l2 hydrolyzes uridylated mRNA TAS Mus musculus 33699 R-PFA-429860 https://reactome.org/PathwayBrowser/#/R-PFA-429860 DCP1-DCP2 complex decaps mRNA IEA Plasmodium falciparum 33699 R-PFA-429978 https://reactome.org/PathwayBrowser/#/R-PFA-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Plasmodium falciparum 33699 R-RNO-111437 https://reactome.org/PathwayBrowser/#/R-RNO-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Rattus norvegicus 33699 R-RNO-111438 https://reactome.org/PathwayBrowser/#/R-RNO-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Rattus norvegicus 33699 R-RNO-111439 https://reactome.org/PathwayBrowser/#/R-RNO-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Rattus norvegicus 33699 R-RNO-158481 https://reactome.org/PathwayBrowser/#/R-RNO-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Rattus norvegicus 33699 R-RNO-159046 https://reactome.org/PathwayBrowser/#/R-RNO-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Rattus norvegicus 33699 R-RNO-429860 https://reactome.org/PathwayBrowser/#/R-RNO-429860 DCP1-DCP2 complex decaps mRNA IEA Rattus norvegicus 33699 R-RNO-429961 https://reactome.org/PathwayBrowser/#/R-RNO-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Rattus norvegicus 33699 R-RNO-429978 https://reactome.org/PathwayBrowser/#/R-RNO-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Rattus norvegicus 33699 R-RNO-430021 https://reactome.org/PathwayBrowser/#/R-RNO-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Rattus norvegicus 33699 R-RNO-430028 https://reactome.org/PathwayBrowser/#/R-RNO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Rattus norvegicus 33699 R-RNO-5419261 https://reactome.org/PathwayBrowser/#/R-RNO-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Rattus norvegicus 33699 R-RNO-5419264 https://reactome.org/PathwayBrowser/#/R-RNO-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Rattus norvegicus 33699 R-RNO-5419271 https://reactome.org/PathwayBrowser/#/R-RNO-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Rattus norvegicus 33699 R-RNO-5419281 https://reactome.org/PathwayBrowser/#/R-RNO-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Rattus norvegicus 33699 R-RNO-77584 https://reactome.org/PathwayBrowser/#/R-RNO-77584 Binding of SLBP to Replication-Dependent Histone Pre-mRNA IEA Rattus norvegicus 33699 R-RNO-77585 https://reactome.org/PathwayBrowser/#/R-RNO-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Rattus norvegicus 33699 R-RNO-77586 https://reactome.org/PathwayBrowser/#/R-RNO-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Rattus norvegicus 33699 R-RNO-77587 https://reactome.org/PathwayBrowser/#/R-RNO-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Rattus norvegicus 33699 R-SCE-429860 https://reactome.org/PathwayBrowser/#/R-SCE-429860 DCP1-DCP2 complex decaps mRNA IEA Saccharomyces cerevisiae 33699 R-SCE-429913 https://reactome.org/PathwayBrowser/#/R-SCE-429913 5' to 3' Exoribonuclease Digestion of Decapped mRNA (yeast) TAS Saccharomyces cerevisiae 33699 R-SCE-429961 https://reactome.org/PathwayBrowser/#/R-SCE-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Saccharomyces cerevisiae 33699 R-SCE-429978 https://reactome.org/PathwayBrowser/#/R-SCE-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Saccharomyces cerevisiae 33699 R-SCE-430021 https://reactome.org/PathwayBrowser/#/R-SCE-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Saccharomyces cerevisiae 33699 R-SCE-430028 https://reactome.org/PathwayBrowser/#/R-SCE-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Saccharomyces cerevisiae 33699 R-SPO-111439 https://reactome.org/PathwayBrowser/#/R-SPO-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Schizosaccharomyces pombe 33699 R-SPO-158481 https://reactome.org/PathwayBrowser/#/R-SPO-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Schizosaccharomyces pombe 33699 R-SPO-429961 https://reactome.org/PathwayBrowser/#/R-SPO-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Schizosaccharomyces pombe 33699 R-SPO-429978 https://reactome.org/PathwayBrowser/#/R-SPO-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Schizosaccharomyces pombe 33699 R-SPO-430028 https://reactome.org/PathwayBrowser/#/R-SPO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Schizosaccharomyces pombe 33699 R-SSC-111437 https://reactome.org/PathwayBrowser/#/R-SSC-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Sus scrofa 33699 R-SSC-111438 https://reactome.org/PathwayBrowser/#/R-SSC-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Sus scrofa 33699 R-SSC-111439 https://reactome.org/PathwayBrowser/#/R-SSC-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Sus scrofa 33699 R-SSC-158481 https://reactome.org/PathwayBrowser/#/R-SSC-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa 33699 R-SSC-159046 https://reactome.org/PathwayBrowser/#/R-SSC-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Sus scrofa 33699 R-SSC-429860 https://reactome.org/PathwayBrowser/#/R-SSC-429860 DCP1-DCP2 complex decaps mRNA IEA Sus scrofa 33699 R-SSC-429955 https://reactome.org/PathwayBrowser/#/R-SSC-429955 CCR4-NOT complex deadenylates mRNA IEA Sus scrofa 33699 R-SSC-429961 https://reactome.org/PathwayBrowser/#/R-SSC-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Sus scrofa 33699 R-SSC-429978 https://reactome.org/PathwayBrowser/#/R-SSC-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Sus scrofa 33699 R-SSC-429992 https://reactome.org/PathwayBrowser/#/R-SSC-429992 PARN deadenylates mRNA IEA Sus scrofa 33699 R-SSC-430021 https://reactome.org/PathwayBrowser/#/R-SSC-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Sus scrofa 33699 R-SSC-430028 https://reactome.org/PathwayBrowser/#/R-SSC-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Sus scrofa 33699 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa 33699 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa 33699 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Sus scrofa 33699 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa 33699 R-SSC-77584 https://reactome.org/PathwayBrowser/#/R-SSC-77584 Binding of SLBP to Replication-Dependent Histone Pre-mRNA IEA Sus scrofa 33699 R-SSC-77585 https://reactome.org/PathwayBrowser/#/R-SSC-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Sus scrofa 33699 R-SSC-77586 https://reactome.org/PathwayBrowser/#/R-SSC-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Sus scrofa 33699 R-SSC-77587 https://reactome.org/PathwayBrowser/#/R-SSC-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Sus scrofa 33699 R-XTR-111437 https://reactome.org/PathwayBrowser/#/R-XTR-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Xenopus tropicalis 33699 R-XTR-111438 https://reactome.org/PathwayBrowser/#/R-XTR-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Xenopus tropicalis 33699 R-XTR-429860 https://reactome.org/PathwayBrowser/#/R-XTR-429860 DCP1-DCP2 complex decaps mRNA IEA Xenopus tropicalis 33699 R-XTR-429955 https://reactome.org/PathwayBrowser/#/R-XTR-429955 CCR4-NOT complex deadenylates mRNA IEA Xenopus tropicalis 33699 R-XTR-429961 https://reactome.org/PathwayBrowser/#/R-XTR-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Xenopus tropicalis 33699 R-XTR-429978 https://reactome.org/PathwayBrowser/#/R-XTR-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Xenopus tropicalis 33699 R-XTR-429992 https://reactome.org/PathwayBrowser/#/R-XTR-429992 PARN deadenylates mRNA IEA Xenopus tropicalis 33699 R-XTR-430028 https://reactome.org/PathwayBrowser/#/R-XTR-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Xenopus tropicalis 33699 R-XTR-77584 https://reactome.org/PathwayBrowser/#/R-XTR-77584 Binding of SLBP to Replication-Dependent Histone Pre-mRNA IEA Xenopus tropicalis 33699 R-XTR-77585 https://reactome.org/PathwayBrowser/#/R-XTR-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Xenopus tropicalis 33699 R-XTR-77586 https://reactome.org/PathwayBrowser/#/R-XTR-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Xenopus tropicalis 33708 R-BTA-1183128 https://reactome.org/PathwayBrowser/#/R-BTA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Bos taurus 33708 R-CFA-1183128 https://reactome.org/PathwayBrowser/#/R-CFA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Canis familiaris 33708 R-GGA-1183128 https://reactome.org/PathwayBrowser/#/R-GGA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Gallus gallus 33708 R-HSA-1183128 https://reactome.org/PathwayBrowser/#/R-HSA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins TAS Homo sapiens 33708 R-MMU-1183128 https://reactome.org/PathwayBrowser/#/R-MMU-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Mus musculus 33708 R-RNO-1183128 https://reactome.org/PathwayBrowser/#/R-RNO-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Rattus norvegicus 33708 R-SSC-1183128 https://reactome.org/PathwayBrowser/#/R-SSC-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Sus scrofa 33708 R-XTR-1183128 https://reactome.org/PathwayBrowser/#/R-XTR-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Xenopus tropicalis 33722 R-BTA-3204311 https://reactome.org/PathwayBrowser/#/R-BTA-3204311 AOX1 oxidises PXL to PDXate IEA Bos taurus 33722 R-BTA-70971 https://reactome.org/PathwayBrowser/#/R-BTA-70971 ACO2 isomerizes citrate IEA Bos taurus 33722 R-BTA-947535 https://reactome.org/PathwayBrowser/#/R-BTA-947535 Cyclisation of GTP to precursor Z IEA Bos taurus 33722 R-BTA-9854368 https://reactome.org/PathwayBrowser/#/R-BTA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Bos taurus 33722 R-BTA-9854405 https://reactome.org/PathwayBrowser/#/R-BTA-9854405 Frataxin transfers Fe2+ to ACO2 IEA Bos taurus 33722 R-CEL-3204311 https://reactome.org/PathwayBrowser/#/R-CEL-3204311 AOX1 oxidises PXL to PDXate IEA Caenorhabditis elegans 33722 R-CEL-70971 https://reactome.org/PathwayBrowser/#/R-CEL-70971 ACO2 isomerizes citrate IEA Caenorhabditis elegans 33722 R-CEL-947535 https://reactome.org/PathwayBrowser/#/R-CEL-947535 Cyclisation of GTP to precursor Z IEA Caenorhabditis elegans 33722 R-CEL-9854368 https://reactome.org/PathwayBrowser/#/R-CEL-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Caenorhabditis elegans 33722 R-CEL-9854405 https://reactome.org/PathwayBrowser/#/R-CEL-9854405 Frataxin transfers Fe2+ to ACO2 IEA Caenorhabditis elegans 33722 R-CFA-70971 https://reactome.org/PathwayBrowser/#/R-CFA-70971 ACO2 isomerizes citrate IEA Canis familiaris 33722 R-CFA-947535 https://reactome.org/PathwayBrowser/#/R-CFA-947535 Cyclisation of GTP to precursor Z IEA Canis familiaris 33722 R-CFA-9854368 https://reactome.org/PathwayBrowser/#/R-CFA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Canis familiaris 33722 R-CFA-9854405 https://reactome.org/PathwayBrowser/#/R-CFA-9854405 Frataxin transfers Fe2+ to ACO2 IEA Canis familiaris 33722 R-DDI-3204311 https://reactome.org/PathwayBrowser/#/R-DDI-3204311 AOX1 oxidises PXL to PDXate IEA Dictyostelium discoideum 33722 R-DDI-70971 https://reactome.org/PathwayBrowser/#/R-DDI-70971 ACO2 isomerizes citrate IEA Dictyostelium discoideum 33722 R-DDI-947535 https://reactome.org/PathwayBrowser/#/R-DDI-947535 Cyclisation of GTP to precursor Z IEA Dictyostelium discoideum 33722 R-DDI-9854368 https://reactome.org/PathwayBrowser/#/R-DDI-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Dictyostelium discoideum 33722 R-DDI-9854405 https://reactome.org/PathwayBrowser/#/R-DDI-9854405 Frataxin transfers Fe2+ to ACO2 IEA Dictyostelium discoideum 33722 R-DME-3204311 https://reactome.org/PathwayBrowser/#/R-DME-3204311 AOX1 oxidises PXL to PDXate IEA Drosophila melanogaster 33722 R-DME-70971 https://reactome.org/PathwayBrowser/#/R-DME-70971 ACO2 isomerizes citrate IEA Drosophila melanogaster 33722 R-DME-947535 https://reactome.org/PathwayBrowser/#/R-DME-947535 Cyclisation of GTP to precursor Z IEA Drosophila melanogaster 33722 R-DME-9854368 https://reactome.org/PathwayBrowser/#/R-DME-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Drosophila melanogaster 33722 R-DME-9854405 https://reactome.org/PathwayBrowser/#/R-DME-9854405 Frataxin transfers Fe2+ to ACO2 IEA Drosophila melanogaster 33722 R-DRE-3204311 https://reactome.org/PathwayBrowser/#/R-DRE-3204311 AOX1 oxidises PXL to PDXate IEA Danio rerio 33722 R-DRE-70971 https://reactome.org/PathwayBrowser/#/R-DRE-70971 ACO2 isomerizes citrate IEA Danio rerio 33722 R-DRE-9854368 https://reactome.org/PathwayBrowser/#/R-DRE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Danio rerio 33722 R-DRE-9854405 https://reactome.org/PathwayBrowser/#/R-DRE-9854405 Frataxin transfers Fe2+ to ACO2 IEA Danio rerio 33722 R-GGA-3204311 https://reactome.org/PathwayBrowser/#/R-GGA-3204311 AOX1 oxidises PXL to PDXate IEA Gallus gallus 33722 R-GGA-70971 https://reactome.org/PathwayBrowser/#/R-GGA-70971 ACO2 isomerizes citrate IEA Gallus gallus 33722 R-GGA-947535 https://reactome.org/PathwayBrowser/#/R-GGA-947535 Cyclisation of GTP to precursor Z IEA Gallus gallus 33722 R-GGA-9854368 https://reactome.org/PathwayBrowser/#/R-GGA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Gallus gallus 33722 R-GGA-9854405 https://reactome.org/PathwayBrowser/#/R-GGA-9854405 Frataxin transfers Fe2+ to ACO2 IEA Gallus gallus 33722 R-HSA-3204311 https://reactome.org/PathwayBrowser/#/R-HSA-3204311 AOX1 oxidises PXL to PDXate TAS Homo sapiens 33722 R-HSA-6789109 https://reactome.org/PathwayBrowser/#/R-HSA-6789109 Superoxide anion reacts with Fe-S cluster TAS Homo sapiens 33722 R-HSA-70971 https://reactome.org/PathwayBrowser/#/R-HSA-70971 ACO2 isomerizes citrate TAS Homo sapiens 33722 R-HSA-947535 https://reactome.org/PathwayBrowser/#/R-HSA-947535 Cyclisation of GTP to precursor Z TAS Homo sapiens 33722 R-HSA-9691363 https://reactome.org/PathwayBrowser/#/R-HSA-9691363 nsp12 binds nsp7 and nsp8 TAS Homo sapiens 33722 R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 33722 R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 33722 R-HSA-9694304 https://reactome.org/PathwayBrowser/#/R-HSA-9694304 nsp14 binds nsp12 IEA Homo sapiens 33722 R-HSA-9694344 https://reactome.org/PathwayBrowser/#/R-HSA-9694344 Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching IEA Homo sapiens 33722 R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 33722 R-HSA-9694454 https://reactome.org/PathwayBrowser/#/R-HSA-9694454 Replication transcription complex binds SARS-CoV-2 genomic RNA TAS Homo sapiens 33722 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 33722 R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 33722 R-HSA-9694495 https://reactome.org/PathwayBrowser/#/R-HSA-9694495 RTC binds SARS-CoV-2 genomic RNA complement (minus strand) IEA Homo sapiens 33722 R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 33722 R-HSA-9694506 https://reactome.org/PathwayBrowser/#/R-HSA-9694506 Synthesis of SARS-CoV-2 plus strand subgenomic mRNAs TAS Homo sapiens 33722 R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 33722 R-HSA-9694524 https://reactome.org/PathwayBrowser/#/R-HSA-9694524 nsp13 binds nsp12 TAS Homo sapiens 33722 R-HSA-9694539 https://reactome.org/PathwayBrowser/#/R-HSA-9694539 nsp15 binds nsp8 IEA Homo sapiens 33722 R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 33722 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 33722 R-HSA-9694576 https://reactome.org/PathwayBrowser/#/R-HSA-9694576 nsp3 binds to nsp7-8 and nsp12-16 IEA Homo sapiens 33722 R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 33722 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 33722 R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 33722 R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 33722 R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 33722 R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 33722 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 33722 R-HSA-9754745 https://reactome.org/PathwayBrowser/#/R-HSA-9754745 IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 33722 R-HSA-9755252 https://reactome.org/PathwayBrowser/#/R-HSA-9755252 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 33722 R-HSA-9755258 https://reactome.org/PathwayBrowser/#/R-HSA-9755258 DDX58 binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 33722 R-HSA-9759709 https://reactome.org/PathwayBrowser/#/R-HSA-9759709 CNBP binds SARS-CoV-2 G-rich RNA TAS Homo sapiens 33722 R-HSA-9760510 https://reactome.org/PathwayBrowser/#/R-HSA-9760510 LARP1 binds SARS-CoV-2 RNA TAS Homo sapiens 33722 R-HSA-9771686 https://reactome.org/PathwayBrowser/#/R-HSA-9771686 nsp12 acquires Fe-S cluster cofactors TAS Homo sapiens 33722 R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 33722 R-HSA-9854368 https://reactome.org/PathwayBrowser/#/R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S TAS Homo sapiens 33722 R-HSA-9854405 https://reactome.org/PathwayBrowser/#/R-HSA-9854405 Frataxin transfers Fe2+ to ACO2 TAS Homo sapiens 33722 R-MMU-3204311 https://reactome.org/PathwayBrowser/#/R-MMU-3204311 AOX1 oxidises PXL to PDXate IEA Mus musculus 33722 R-MMU-70971 https://reactome.org/PathwayBrowser/#/R-MMU-70971 ACO2 isomerizes citrate IEA Mus musculus 33722 R-MMU-947535 https://reactome.org/PathwayBrowser/#/R-MMU-947535 Cyclisation of GTP to precursor Z IEA Mus musculus 33722 R-MMU-9854368 https://reactome.org/PathwayBrowser/#/R-MMU-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Mus musculus 33722 R-MMU-9854405 https://reactome.org/PathwayBrowser/#/R-MMU-9854405 Frataxin transfers Fe2+ to ACO2 IEA Mus musculus 33722 R-MTU-936703 https://reactome.org/PathwayBrowser/#/R-MTU-936703 sulfite is reduced to sulfide TAS Mycobacterium tuberculosis 33722 R-RNO-3204311 https://reactome.org/PathwayBrowser/#/R-RNO-3204311 AOX1 oxidises PXL to PDXate IEA Rattus norvegicus 33722 R-RNO-70971 https://reactome.org/PathwayBrowser/#/R-RNO-70971 ACO2 isomerizes citrate IEA Rattus norvegicus 33722 R-RNO-947535 https://reactome.org/PathwayBrowser/#/R-RNO-947535 Cyclisation of GTP to precursor Z IEA Rattus norvegicus 33722 R-RNO-9854368 https://reactome.org/PathwayBrowser/#/R-RNO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Rattus norvegicus 33722 R-RNO-9854405 https://reactome.org/PathwayBrowser/#/R-RNO-9854405 Frataxin transfers Fe2+ to ACO2 IEA Rattus norvegicus 33722 R-SCE-70971 https://reactome.org/PathwayBrowser/#/R-SCE-70971 ACO2 isomerizes citrate IEA Saccharomyces cerevisiae 33722 R-SCE-9854368 https://reactome.org/PathwayBrowser/#/R-SCE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Saccharomyces cerevisiae 33722 R-SCE-9854405 https://reactome.org/PathwayBrowser/#/R-SCE-9854405 Frataxin transfers Fe2+ to ACO2 IEA Saccharomyces cerevisiae 33722 R-SPO-70971 https://reactome.org/PathwayBrowser/#/R-SPO-70971 ACO2 isomerizes citrate IEA Schizosaccharomyces pombe 33722 R-SPO-9854368 https://reactome.org/PathwayBrowser/#/R-SPO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Schizosaccharomyces pombe 33722 R-SPO-9854405 https://reactome.org/PathwayBrowser/#/R-SPO-9854405 Frataxin transfers Fe2+ to ACO2 IEA Schizosaccharomyces pombe 33722 R-SSC-3204311 https://reactome.org/PathwayBrowser/#/R-SSC-3204311 AOX1 oxidises PXL to PDXate IEA Sus scrofa 33722 R-SSC-70971 https://reactome.org/PathwayBrowser/#/R-SSC-70971 ACO2 isomerizes citrate IEA Sus scrofa 33722 R-SSC-947535 https://reactome.org/PathwayBrowser/#/R-SSC-947535 Cyclisation of GTP to precursor Z IEA Sus scrofa 33722 R-SSC-9854368 https://reactome.org/PathwayBrowser/#/R-SSC-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Sus scrofa 33722 R-SSC-9854405 https://reactome.org/PathwayBrowser/#/R-SSC-9854405 Frataxin transfers Fe2+ to ACO2 IEA Sus scrofa 33722 R-XTR-3204311 https://reactome.org/PathwayBrowser/#/R-XTR-3204311 AOX1 oxidises PXL to PDXate IEA Xenopus tropicalis 33722 R-XTR-70971 https://reactome.org/PathwayBrowser/#/R-XTR-70971 ACO2 isomerizes citrate IEA Xenopus tropicalis 33722 R-XTR-947535 https://reactome.org/PathwayBrowser/#/R-XTR-947535 Cyclisation of GTP to precursor Z IEA Xenopus tropicalis 33722 R-XTR-9854368 https://reactome.org/PathwayBrowser/#/R-XTR-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Xenopus tropicalis 33723 R-MTU-936703 https://reactome.org/PathwayBrowser/#/R-MTU-936703 sulfite is reduced to sulfide TAS Mycobacterium tuberculosis 33737 R-BTA-1362408 https://reactome.org/PathwayBrowser/#/R-BTA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Bos taurus 33737 R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 33737 R-BTA-2395512 https://reactome.org/PathwayBrowser/#/R-BTA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Bos taurus 33737 R-BTA-6793591 https://reactome.org/PathwayBrowser/#/R-BTA-6793591 LIAS synthesizes lipoyl-GCSH IEA Bos taurus 33737 R-CEL-1362408 https://reactome.org/PathwayBrowser/#/R-CEL-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Caenorhabditis elegans 33737 R-CEL-2395512 https://reactome.org/PathwayBrowser/#/R-CEL-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Caenorhabditis elegans 33737 R-CFA-1362408 https://reactome.org/PathwayBrowser/#/R-CFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Canis familiaris 33737 R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 33737 R-CFA-2395512 https://reactome.org/PathwayBrowser/#/R-CFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Canis familiaris 33737 R-CFA-6793591 https://reactome.org/PathwayBrowser/#/R-CFA-6793591 LIAS synthesizes lipoyl-GCSH IEA Canis familiaris 33737 R-DDI-1362408 https://reactome.org/PathwayBrowser/#/R-DDI-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Dictyostelium discoideum 33737 R-DDI-2395512 https://reactome.org/PathwayBrowser/#/R-DDI-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Dictyostelium discoideum 33737 R-DME-1362408 https://reactome.org/PathwayBrowser/#/R-DME-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Drosophila melanogaster 33737 R-DME-2395512 https://reactome.org/PathwayBrowser/#/R-DME-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Drosophila melanogaster 33737 R-DME-6793591 https://reactome.org/PathwayBrowser/#/R-DME-6793591 LIAS synthesizes lipoyl-GCSH IEA Drosophila melanogaster 33737 R-DRE-1362408 https://reactome.org/PathwayBrowser/#/R-DRE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Danio rerio 33737 R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 33737 R-DRE-2395512 https://reactome.org/PathwayBrowser/#/R-DRE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Danio rerio 33737 R-DRE-6793591 https://reactome.org/PathwayBrowser/#/R-DRE-6793591 LIAS synthesizes lipoyl-GCSH IEA Danio rerio 33737 R-GGA-1362408 https://reactome.org/PathwayBrowser/#/R-GGA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Gallus gallus 33737 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 33737 R-GGA-2395512 https://reactome.org/PathwayBrowser/#/R-GGA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Gallus gallus 33737 R-GGA-6793591 https://reactome.org/PathwayBrowser/#/R-GGA-6793591 LIAS synthesizes lipoyl-GCSH IEA Gallus gallus 33737 R-HSA-1362408 https://reactome.org/PathwayBrowser/#/R-HSA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster TAS Homo sapiens 33737 R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 33737 R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB IEA Homo sapiens 33737 R-HSA-2395512 https://reactome.org/PathwayBrowser/#/R-HSA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) TAS Homo sapiens 33737 R-HSA-2564824 https://reactome.org/PathwayBrowser/#/R-HSA-2564824 NADPH reduces NDOR1:CIAPIN1 IEA Homo sapiens 33737 R-HSA-6793591 https://reactome.org/PathwayBrowser/#/R-HSA-6793591 LIAS synthesizes lipoyl-GCSH TAS Homo sapiens 33737 R-MMU-1362408 https://reactome.org/PathwayBrowser/#/R-MMU-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Mus musculus 33737 R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 33737 R-MMU-2395512 https://reactome.org/PathwayBrowser/#/R-MMU-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Mus musculus 33737 R-MMU-6793591 https://reactome.org/PathwayBrowser/#/R-MMU-6793591 LIAS synthesizes lipoyl-GCSH IEA Mus musculus 33737 R-PFA-1362408 https://reactome.org/PathwayBrowser/#/R-PFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Plasmodium falciparum 33737 R-PFA-2395512 https://reactome.org/PathwayBrowser/#/R-PFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Plasmodium falciparum 33737 R-RNO-1362408 https://reactome.org/PathwayBrowser/#/R-RNO-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Rattus norvegicus 33737 R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 33737 R-RNO-2395512 https://reactome.org/PathwayBrowser/#/R-RNO-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Rattus norvegicus 33737 R-RNO-6793591 https://reactome.org/PathwayBrowser/#/R-RNO-6793591 LIAS synthesizes lipoyl-GCSH IEA Rattus norvegicus 33737 R-SCE-1362408 https://reactome.org/PathwayBrowser/#/R-SCE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Saccharomyces cerevisiae 33737 R-SCE-2162292 https://reactome.org/PathwayBrowser/#/R-SCE-2162292 HHB is hydroxylated to DHHB by Coq6 TAS Saccharomyces cerevisiae 33737 R-SCE-2395512 https://reactome.org/PathwayBrowser/#/R-SCE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Saccharomyces cerevisiae 33737 R-SCE-2564819 https://reactome.org/PathwayBrowser/#/R-SCE-2564819 NADPH reduces TAH18:DRE2 TAS Saccharomyces cerevisiae 33737 R-SSC-1362408 https://reactome.org/PathwayBrowser/#/R-SSC-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Sus scrofa 33737 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 33737 R-SSC-2395512 https://reactome.org/PathwayBrowser/#/R-SSC-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Sus scrofa 33737 R-SSC-6793591 https://reactome.org/PathwayBrowser/#/R-SSC-6793591 LIAS synthesizes lipoyl-GCSH IEA Sus scrofa 33737 R-XTR-1362408 https://reactome.org/PathwayBrowser/#/R-XTR-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Xenopus tropicalis 33737 R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 33737 R-XTR-2395512 https://reactome.org/PathwayBrowser/#/R-XTR-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Xenopus tropicalis 33738 R-BTA-1362408 https://reactome.org/PathwayBrowser/#/R-BTA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Bos taurus 33738 R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 33738 R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 33738 R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 33738 R-BTA-2395512 https://reactome.org/PathwayBrowser/#/R-BTA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Bos taurus 33738 R-BTA-6783221 https://reactome.org/PathwayBrowser/#/R-BTA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Bos taurus 33738 R-BTA-6793591 https://reactome.org/PathwayBrowser/#/R-BTA-6793591 LIAS synthesizes lipoyl-GCSH IEA Bos taurus 33738 R-CEL-1362408 https://reactome.org/PathwayBrowser/#/R-CEL-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Caenorhabditis elegans 33738 R-CEL-2395512 https://reactome.org/PathwayBrowser/#/R-CEL-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Caenorhabditis elegans 33738 R-CEL-6783221 https://reactome.org/PathwayBrowser/#/R-CEL-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Caenorhabditis elegans 33738 R-CFA-1362408 https://reactome.org/PathwayBrowser/#/R-CFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Canis familiaris 33738 R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 33738 R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 33738 R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 33738 R-CFA-2395512 https://reactome.org/PathwayBrowser/#/R-CFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Canis familiaris 33738 R-CFA-6783221 https://reactome.org/PathwayBrowser/#/R-CFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Canis familiaris 33738 R-CFA-6793591 https://reactome.org/PathwayBrowser/#/R-CFA-6793591 LIAS synthesizes lipoyl-GCSH IEA Canis familiaris 33738 R-DDI-1362408 https://reactome.org/PathwayBrowser/#/R-DDI-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Dictyostelium discoideum 33738 R-DDI-2395512 https://reactome.org/PathwayBrowser/#/R-DDI-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Dictyostelium discoideum 33738 R-DDI-6783221 https://reactome.org/PathwayBrowser/#/R-DDI-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Dictyostelium discoideum 33738 R-DME-1362408 https://reactome.org/PathwayBrowser/#/R-DME-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Drosophila melanogaster 33738 R-DME-2395512 https://reactome.org/PathwayBrowser/#/R-DME-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Drosophila melanogaster 33738 R-DME-6783221 https://reactome.org/PathwayBrowser/#/R-DME-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Drosophila melanogaster 33738 R-DME-6793591 https://reactome.org/PathwayBrowser/#/R-DME-6793591 LIAS synthesizes lipoyl-GCSH IEA Drosophila melanogaster 33738 R-DRE-1362408 https://reactome.org/PathwayBrowser/#/R-DRE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Danio rerio 33738 R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 33738 R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 33738 R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 33738 R-DRE-2395512 https://reactome.org/PathwayBrowser/#/R-DRE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Danio rerio 33738 R-DRE-6783221 https://reactome.org/PathwayBrowser/#/R-DRE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Danio rerio 33738 R-DRE-6793591 https://reactome.org/PathwayBrowser/#/R-DRE-6793591 LIAS synthesizes lipoyl-GCSH IEA Danio rerio 33738 R-GGA-1362408 https://reactome.org/PathwayBrowser/#/R-GGA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Gallus gallus 33738 R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 33738 R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 33738 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 33738 R-GGA-2395512 https://reactome.org/PathwayBrowser/#/R-GGA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Gallus gallus 33738 R-GGA-6783221 https://reactome.org/PathwayBrowser/#/R-GGA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Gallus gallus 33738 R-GGA-6793591 https://reactome.org/PathwayBrowser/#/R-GGA-6793591 LIAS synthesizes lipoyl-GCSH IEA Gallus gallus 33738 R-HSA-1362408 https://reactome.org/PathwayBrowser/#/R-HSA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster TAS Homo sapiens 33738 R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 33738 R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 33738 R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 33738 R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB IEA Homo sapiens 33738 R-HSA-2395512 https://reactome.org/PathwayBrowser/#/R-HSA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) TAS Homo sapiens 33738 R-HSA-2564824 https://reactome.org/PathwayBrowser/#/R-HSA-2564824 NADPH reduces NDOR1:CIAPIN1 IEA Homo sapiens 33738 R-HSA-2564826 https://reactome.org/PathwayBrowser/#/R-HSA-2564826 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold IEA Homo sapiens 33738 R-HSA-5580269 https://reactome.org/PathwayBrowser/#/R-HSA-5580269 Defective CYP11A1 does not cleave 20a,22b-DHCHOL TAS Homo sapiens 33738 R-HSA-6783221 https://reactome.org/PathwayBrowser/#/R-HSA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT TAS Homo sapiens 33738 R-HSA-6793591 https://reactome.org/PathwayBrowser/#/R-HSA-6793591 LIAS synthesizes lipoyl-GCSH TAS Homo sapiens 33738 R-MMU-1362408 https://reactome.org/PathwayBrowser/#/R-MMU-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Mus musculus 33738 R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 33738 R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 33738 R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 33738 R-MMU-2395512 https://reactome.org/PathwayBrowser/#/R-MMU-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Mus musculus 33738 R-MMU-6783221 https://reactome.org/PathwayBrowser/#/R-MMU-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Mus musculus 33738 R-MMU-6793591 https://reactome.org/PathwayBrowser/#/R-MMU-6793591 LIAS synthesizes lipoyl-GCSH IEA Mus musculus 33738 R-PFA-1362408 https://reactome.org/PathwayBrowser/#/R-PFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Plasmodium falciparum 33738 R-PFA-2395512 https://reactome.org/PathwayBrowser/#/R-PFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Plasmodium falciparum 33738 R-PFA-6783221 https://reactome.org/PathwayBrowser/#/R-PFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Plasmodium falciparum 33738 R-RNO-1362408 https://reactome.org/PathwayBrowser/#/R-RNO-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Rattus norvegicus 33738 R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 33738 R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 33738 R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 33738 R-RNO-2395512 https://reactome.org/PathwayBrowser/#/R-RNO-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Rattus norvegicus 33738 R-RNO-6783221 https://reactome.org/PathwayBrowser/#/R-RNO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Rattus norvegicus 33738 R-RNO-6793591 https://reactome.org/PathwayBrowser/#/R-RNO-6793591 LIAS synthesizes lipoyl-GCSH IEA Rattus norvegicus 33738 R-SCE-1362408 https://reactome.org/PathwayBrowser/#/R-SCE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Saccharomyces cerevisiae 33738 R-SCE-2162292 https://reactome.org/PathwayBrowser/#/R-SCE-2162292 HHB is hydroxylated to DHHB by Coq6 TAS Saccharomyces cerevisiae 33738 R-SCE-2395512 https://reactome.org/PathwayBrowser/#/R-SCE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Saccharomyces cerevisiae 33738 R-SCE-2564819 https://reactome.org/PathwayBrowser/#/R-SCE-2564819 NADPH reduces TAH18:DRE2 TAS Saccharomyces cerevisiae 33738 R-SCE-2564822 https://reactome.org/PathwayBrowser/#/R-SCE-2564822 4Fe-4S cluster assembles on CFD1:NBP35 scaffold TAS Saccharomyces cerevisiae 33738 R-SCE-6783221 https://reactome.org/PathwayBrowser/#/R-SCE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Saccharomyces cerevisiae 33738 R-SPO-6783221 https://reactome.org/PathwayBrowser/#/R-SPO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Schizosaccharomyces pombe 33738 R-SSC-1362408 https://reactome.org/PathwayBrowser/#/R-SSC-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Sus scrofa 33738 R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 33738 R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 33738 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 33738 R-SSC-2395512 https://reactome.org/PathwayBrowser/#/R-SSC-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Sus scrofa 33738 R-SSC-6783221 https://reactome.org/PathwayBrowser/#/R-SSC-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Sus scrofa 33738 R-SSC-6793591 https://reactome.org/PathwayBrowser/#/R-SSC-6793591 LIAS synthesizes lipoyl-GCSH IEA Sus scrofa 33738 R-XTR-1362408 https://reactome.org/PathwayBrowser/#/R-XTR-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Xenopus tropicalis 33738 R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 33738 R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 33738 R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 33738 R-XTR-2395512 https://reactome.org/PathwayBrowser/#/R-XTR-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Xenopus tropicalis 33738 R-XTR-6783221 https://reactome.org/PathwayBrowser/#/R-XTR-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Xenopus tropicalis 33739 R-BTA-1362408 https://reactome.org/PathwayBrowser/#/R-BTA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Bos taurus 33739 R-BTA-8878815 https://reactome.org/PathwayBrowser/#/R-BTA-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Bos taurus 33739 R-BTA-916855 https://reactome.org/PathwayBrowser/#/R-BTA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Bos taurus 33739 R-BTA-9854984 https://reactome.org/PathwayBrowser/#/R-BTA-9854984 Transfer of Fe-S clusters to SDHB IEA Bos taurus 33739 R-BTA-9855212 https://reactome.org/PathwayBrowser/#/R-BTA-9855212 SDHA binds to SDHB IEA Bos taurus 33739 R-BTA-9855252 https://reactome.org/PathwayBrowser/#/R-BTA-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Bos taurus 33739 R-CEL-1362408 https://reactome.org/PathwayBrowser/#/R-CEL-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Caenorhabditis elegans 33739 R-CEL-8878815 https://reactome.org/PathwayBrowser/#/R-CEL-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Caenorhabditis elegans 33739 R-CEL-916855 https://reactome.org/PathwayBrowser/#/R-CEL-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Caenorhabditis elegans 33739 R-CFA-1362408 https://reactome.org/PathwayBrowser/#/R-CFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Canis familiaris 33739 R-CFA-8878815 https://reactome.org/PathwayBrowser/#/R-CFA-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Canis familiaris 33739 R-CFA-916855 https://reactome.org/PathwayBrowser/#/R-CFA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Canis familiaris 33739 R-DDI-1362408 https://reactome.org/PathwayBrowser/#/R-DDI-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Dictyostelium discoideum 33739 R-DDI-8878815 https://reactome.org/PathwayBrowser/#/R-DDI-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Dictyostelium discoideum 33739 R-DDI-916855 https://reactome.org/PathwayBrowser/#/R-DDI-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Dictyostelium discoideum 33739 R-DME-1362408 https://reactome.org/PathwayBrowser/#/R-DME-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Drosophila melanogaster 33739 R-DME-8878815 https://reactome.org/PathwayBrowser/#/R-DME-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Drosophila melanogaster 33739 R-DME-916855 https://reactome.org/PathwayBrowser/#/R-DME-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Drosophila melanogaster 33739 R-DRE-1362408 https://reactome.org/PathwayBrowser/#/R-DRE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Danio rerio 33739 R-DRE-916855 https://reactome.org/PathwayBrowser/#/R-DRE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Danio rerio 33739 R-GGA-1362408 https://reactome.org/PathwayBrowser/#/R-GGA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Gallus gallus 33739 R-GGA-8878815 https://reactome.org/PathwayBrowser/#/R-GGA-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Gallus gallus 33739 R-GGA-916855 https://reactome.org/PathwayBrowser/#/R-GGA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Gallus gallus 33739 R-HSA-1362408 https://reactome.org/PathwayBrowser/#/R-HSA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster TAS Homo sapiens 33739 R-HSA-8878815 https://reactome.org/PathwayBrowser/#/R-HSA-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 TAS Homo sapiens 33739 R-HSA-916855 https://reactome.org/PathwayBrowser/#/R-HSA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA TAS Homo sapiens 33739 R-HSA-9854984 https://reactome.org/PathwayBrowser/#/R-HSA-9854984 Transfer of Fe-S clusters to SDHB TAS Homo sapiens 33739 R-HSA-9855212 https://reactome.org/PathwayBrowser/#/R-HSA-9855212 SDHA binds to SDHB TAS Homo sapiens 33739 R-HSA-9855252 https://reactome.org/PathwayBrowser/#/R-HSA-9855252 SDHA:SDHB binds to SDHC:SDHD TAS Homo sapiens 33739 R-MMU-1362408 https://reactome.org/PathwayBrowser/#/R-MMU-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Mus musculus 33739 R-MMU-8878815 https://reactome.org/PathwayBrowser/#/R-MMU-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Mus musculus 33739 R-MMU-916855 https://reactome.org/PathwayBrowser/#/R-MMU-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Mus musculus 33739 R-MMU-9854984 https://reactome.org/PathwayBrowser/#/R-MMU-9854984 Transfer of Fe-S clusters to SDHB IEA Mus musculus 33739 R-MMU-9855212 https://reactome.org/PathwayBrowser/#/R-MMU-9855212 SDHA binds to SDHB IEA Mus musculus 33739 R-MMU-9855252 https://reactome.org/PathwayBrowser/#/R-MMU-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Mus musculus 33739 R-PFA-1362408 https://reactome.org/PathwayBrowser/#/R-PFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Plasmodium falciparum 33739 R-RNO-1362408 https://reactome.org/PathwayBrowser/#/R-RNO-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Rattus norvegicus 33739 R-RNO-8878815 https://reactome.org/PathwayBrowser/#/R-RNO-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Rattus norvegicus 33739 R-RNO-916855 https://reactome.org/PathwayBrowser/#/R-RNO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Rattus norvegicus 33739 R-SCE-1362408 https://reactome.org/PathwayBrowser/#/R-SCE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Saccharomyces cerevisiae 33739 R-SCE-8878815 https://reactome.org/PathwayBrowser/#/R-SCE-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Saccharomyces cerevisiae 33739 R-SCE-916855 https://reactome.org/PathwayBrowser/#/R-SCE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Saccharomyces cerevisiae 33739 R-SPO-8878815 https://reactome.org/PathwayBrowser/#/R-SPO-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Schizosaccharomyces pombe 33739 R-SPO-916855 https://reactome.org/PathwayBrowser/#/R-SPO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Schizosaccharomyces pombe 33739 R-SSC-1362408 https://reactome.org/PathwayBrowser/#/R-SSC-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Sus scrofa 33739 R-SSC-8878815 https://reactome.org/PathwayBrowser/#/R-SSC-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Sus scrofa 33739 R-SSC-916855 https://reactome.org/PathwayBrowser/#/R-SSC-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Sus scrofa 33739 R-SSC-9854984 https://reactome.org/PathwayBrowser/#/R-SSC-9854984 Transfer of Fe-S clusters to SDHB IEA Sus scrofa 33739 R-SSC-9855212 https://reactome.org/PathwayBrowser/#/R-SSC-9855212 SDHA binds to SDHB IEA Sus scrofa 33739 R-SSC-9855252 https://reactome.org/PathwayBrowser/#/R-SSC-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Sus scrofa 33739 R-XTR-1362408 https://reactome.org/PathwayBrowser/#/R-XTR-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Xenopus tropicalis 33739 R-XTR-916855 https://reactome.org/PathwayBrowser/#/R-XTR-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Xenopus tropicalis 33739 R-XTR-9855212 https://reactome.org/PathwayBrowser/#/R-XTR-9855212 SDHA binds to SDHB IEA Xenopus tropicalis 33739 R-XTR-9855252 https://reactome.org/PathwayBrowser/#/R-XTR-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Xenopus tropicalis 33751 R-HSA-6789109 https://reactome.org/PathwayBrowser/#/R-HSA-6789109 Superoxide anion reacts with Fe-S cluster TAS Homo sapiens 3380 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 3380 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 3380 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 3380 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 3380 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 3380 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 3380 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 3380 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 3380 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 3380 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 3380 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 3380 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 3380 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 3380 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 3380 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 3380 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 3380 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 3380 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 3380 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 3380 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 33837 R-BTA-1022129 https://reactome.org/PathwayBrowser/#/R-BTA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Bos taurus 33837 R-BTA-1022133 https://reactome.org/PathwayBrowser/#/R-BTA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Bos taurus 33837 R-BTA-1028788 https://reactome.org/PathwayBrowser/#/R-BTA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Bos taurus 33837 R-BTA-5693807 https://reactome.org/PathwayBrowser/#/R-BTA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Bos taurus 33837 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 33837 R-BTA-975902 https://reactome.org/PathwayBrowser/#/R-BTA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Bos taurus 33837 R-BTA-975903 https://reactome.org/PathwayBrowser/#/R-BTA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Bos taurus 33837 R-BTA-975916 https://reactome.org/PathwayBrowser/#/R-BTA-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Bos taurus 33837 R-BTA-975919 https://reactome.org/PathwayBrowser/#/R-BTA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Bos taurus 33837 R-BTA-975926 https://reactome.org/PathwayBrowser/#/R-BTA-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Bos taurus 33837 R-CEL-1028788 https://reactome.org/PathwayBrowser/#/R-CEL-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Caenorhabditis elegans 33837 R-CEL-5693807 https://reactome.org/PathwayBrowser/#/R-CEL-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Caenorhabditis elegans 33837 R-CEL-975916 https://reactome.org/PathwayBrowser/#/R-CEL-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Caenorhabditis elegans 33837 R-CFA-1022129 https://reactome.org/PathwayBrowser/#/R-CFA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Canis familiaris 33837 R-CFA-1022133 https://reactome.org/PathwayBrowser/#/R-CFA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Canis familiaris 33837 R-CFA-1028788 https://reactome.org/PathwayBrowser/#/R-CFA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Canis familiaris 33837 R-CFA-5693807 https://reactome.org/PathwayBrowser/#/R-CFA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Canis familiaris 33837 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 33837 R-CFA-975902 https://reactome.org/PathwayBrowser/#/R-CFA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Canis familiaris 33837 R-CFA-975903 https://reactome.org/PathwayBrowser/#/R-CFA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Canis familiaris 33837 R-CFA-975916 https://reactome.org/PathwayBrowser/#/R-CFA-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Canis familiaris 33837 R-CFA-975919 https://reactome.org/PathwayBrowser/#/R-CFA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Canis familiaris 33837 R-DDI-5693807 https://reactome.org/PathwayBrowser/#/R-DDI-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Dictyostelium discoideum 33837 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 33837 R-DDI-975926 https://reactome.org/PathwayBrowser/#/R-DDI-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Dictyostelium discoideum 33837 R-DME-1028788 https://reactome.org/PathwayBrowser/#/R-DME-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Drosophila melanogaster 33837 R-DME-5693807 https://reactome.org/PathwayBrowser/#/R-DME-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Drosophila melanogaster 33837 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 33837 R-DME-975902 https://reactome.org/PathwayBrowser/#/R-DME-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Drosophila melanogaster 33837 R-DME-975903 https://reactome.org/PathwayBrowser/#/R-DME-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Drosophila melanogaster 33837 R-DME-975919 https://reactome.org/PathwayBrowser/#/R-DME-975919 Addition of galactose by beta 4-galactosyltransferases IEA Drosophila melanogaster 33837 R-DME-975926 https://reactome.org/PathwayBrowser/#/R-DME-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Drosophila melanogaster 33837 R-DRE-1022129 https://reactome.org/PathwayBrowser/#/R-DRE-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Danio rerio 33837 R-DRE-1022133 https://reactome.org/PathwayBrowser/#/R-DRE-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Danio rerio 33837 R-DRE-1028788 https://reactome.org/PathwayBrowser/#/R-DRE-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Danio rerio 33837 R-DRE-5693807 https://reactome.org/PathwayBrowser/#/R-DRE-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Danio rerio 33837 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 33837 R-DRE-975903 https://reactome.org/PathwayBrowser/#/R-DRE-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Danio rerio 33837 R-DRE-975916 https://reactome.org/PathwayBrowser/#/R-DRE-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Danio rerio 33837 R-DRE-975919 https://reactome.org/PathwayBrowser/#/R-DRE-975919 Addition of galactose by beta 4-galactosyltransferases IEA Danio rerio 33837 R-GGA-1022129 https://reactome.org/PathwayBrowser/#/R-GGA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Gallus gallus 33837 R-GGA-1022133 https://reactome.org/PathwayBrowser/#/R-GGA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Gallus gallus 33837 R-GGA-1028788 https://reactome.org/PathwayBrowser/#/R-GGA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Gallus gallus 33837 R-GGA-5693807 https://reactome.org/PathwayBrowser/#/R-GGA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Gallus gallus 33837 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 33837 R-GGA-975902 https://reactome.org/PathwayBrowser/#/R-GGA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Gallus gallus 33837 R-GGA-975903 https://reactome.org/PathwayBrowser/#/R-GGA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Gallus gallus 33837 R-GGA-975916 https://reactome.org/PathwayBrowser/#/R-GGA-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Gallus gallus 33837 R-GGA-975919 https://reactome.org/PathwayBrowser/#/R-GGA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Gallus gallus 33837 R-GGA-975926 https://reactome.org/PathwayBrowser/#/R-GGA-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Gallus gallus 33837 R-HSA-1022129 https://reactome.org/PathwayBrowser/#/R-HSA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans TAS Homo sapiens 33837 R-HSA-1022133 https://reactome.org/PathwayBrowser/#/R-HSA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans TAS Homo sapiens 33837 R-HSA-1028788 https://reactome.org/PathwayBrowser/#/R-HSA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP TAS Homo sapiens 33837 R-HSA-5693807 https://reactome.org/PathwayBrowser/#/R-HSA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc TAS Homo sapiens 33837 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 33837 R-HSA-975902 https://reactome.org/PathwayBrowser/#/R-HSA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans TAS Homo sapiens 33837 R-HSA-975903 https://reactome.org/PathwayBrowser/#/R-HSA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV TAS Homo sapiens 33837 R-HSA-975916 https://reactome.org/PathwayBrowser/#/R-HSA-975916 Addition of GlcNAc to position 5 by MGAT5 TAS Homo sapiens 33837 R-HSA-975919 https://reactome.org/PathwayBrowser/#/R-HSA-975919 Addition of galactose by beta 4-galactosyltransferases TAS Homo sapiens 33837 R-HSA-975926 https://reactome.org/PathwayBrowser/#/R-HSA-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 TAS Homo sapiens 33837 R-MMU-1022129 https://reactome.org/PathwayBrowser/#/R-MMU-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Mus musculus 33837 R-MMU-1022133 https://reactome.org/PathwayBrowser/#/R-MMU-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Mus musculus 33837 R-MMU-1028788 https://reactome.org/PathwayBrowser/#/R-MMU-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Mus musculus 33837 R-MMU-5693807 https://reactome.org/PathwayBrowser/#/R-MMU-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Mus musculus 33837 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 33837 R-MMU-975902 https://reactome.org/PathwayBrowser/#/R-MMU-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Mus musculus 33837 R-MMU-975903 https://reactome.org/PathwayBrowser/#/R-MMU-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Mus musculus 33837 R-MMU-975916 https://reactome.org/PathwayBrowser/#/R-MMU-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Mus musculus 33837 R-MMU-975919 https://reactome.org/PathwayBrowser/#/R-MMU-975919 Addition of galactose by beta 4-galactosyltransferases IEA Mus musculus 33837 R-MMU-975926 https://reactome.org/PathwayBrowser/#/R-MMU-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Mus musculus 33837 R-RNO-1022129 https://reactome.org/PathwayBrowser/#/R-RNO-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Rattus norvegicus 33837 R-RNO-1022133 https://reactome.org/PathwayBrowser/#/R-RNO-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Rattus norvegicus 33837 R-RNO-1028788 https://reactome.org/PathwayBrowser/#/R-RNO-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Rattus norvegicus 33837 R-RNO-5693807 https://reactome.org/PathwayBrowser/#/R-RNO-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Rattus norvegicus 33837 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 33837 R-RNO-975902 https://reactome.org/PathwayBrowser/#/R-RNO-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Rattus norvegicus 33837 R-RNO-975903 https://reactome.org/PathwayBrowser/#/R-RNO-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Rattus norvegicus 33837 R-RNO-975916 https://reactome.org/PathwayBrowser/#/R-RNO-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Rattus norvegicus 33837 R-RNO-975919 https://reactome.org/PathwayBrowser/#/R-RNO-975919 Addition of galactose by beta 4-galactosyltransferases IEA Rattus norvegicus 33837 R-RNO-975926 https://reactome.org/PathwayBrowser/#/R-RNO-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Rattus norvegicus 33837 R-SSC-1022129 https://reactome.org/PathwayBrowser/#/R-SSC-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Sus scrofa 33837 R-SSC-1022133 https://reactome.org/PathwayBrowser/#/R-SSC-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Sus scrofa 33837 R-SSC-1028788 https://reactome.org/PathwayBrowser/#/R-SSC-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Sus scrofa 33837 R-SSC-5693807 https://reactome.org/PathwayBrowser/#/R-SSC-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Sus scrofa 33837 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 33837 R-SSC-975902 https://reactome.org/PathwayBrowser/#/R-SSC-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Sus scrofa 33837 R-SSC-975903 https://reactome.org/PathwayBrowser/#/R-SSC-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Sus scrofa 33837 R-SSC-975916 https://reactome.org/PathwayBrowser/#/R-SSC-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Sus scrofa 33837 R-SSC-975919 https://reactome.org/PathwayBrowser/#/R-SSC-975919 Addition of galactose by beta 4-galactosyltransferases IEA Sus scrofa 33837 R-SSC-975926 https://reactome.org/PathwayBrowser/#/R-SSC-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Sus scrofa 33837 R-XTR-1022129 https://reactome.org/PathwayBrowser/#/R-XTR-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Xenopus tropicalis 33837 R-XTR-1022133 https://reactome.org/PathwayBrowser/#/R-XTR-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Xenopus tropicalis 33837 R-XTR-1028788 https://reactome.org/PathwayBrowser/#/R-XTR-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Xenopus tropicalis 33837 R-XTR-5693807 https://reactome.org/PathwayBrowser/#/R-XTR-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Xenopus tropicalis 33837 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 33837 R-XTR-975902 https://reactome.org/PathwayBrowser/#/R-XTR-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Xenopus tropicalis 33837 R-XTR-975903 https://reactome.org/PathwayBrowser/#/R-XTR-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Xenopus tropicalis 33837 R-XTR-975916 https://reactome.org/PathwayBrowser/#/R-XTR-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Xenopus tropicalis 33837 R-XTR-975919 https://reactome.org/PathwayBrowser/#/R-XTR-975919 Addition of galactose by beta 4-galactosyltransferases IEA Xenopus tropicalis 33837 R-XTR-975926 https://reactome.org/PathwayBrowser/#/R-XTR-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Xenopus tropicalis 33913 R-BTA-3245898 https://reactome.org/PathwayBrowser/#/R-BTA-3245898 TCN1 binds correnoids in the circulation IEA Bos taurus 33913 R-CFA-3245898 https://reactome.org/PathwayBrowser/#/R-CFA-3245898 TCN1 binds correnoids in the circulation IEA Canis familiaris 33913 R-DME-3245898 https://reactome.org/PathwayBrowser/#/R-DME-3245898 TCN1 binds correnoids in the circulation IEA Drosophila melanogaster 33913 R-HSA-3245898 https://reactome.org/PathwayBrowser/#/R-HSA-3245898 TCN1 binds correnoids in the circulation TAS Homo sapiens 33913 R-SSC-3245898 https://reactome.org/PathwayBrowser/#/R-SSC-3245898 TCN1 binds correnoids in the circulation IEA Sus scrofa 33913 R-XTR-3245898 https://reactome.org/PathwayBrowser/#/R-XTR-3245898 TCN1 binds correnoids in the circulation IEA Xenopus tropicalis 34037 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 34037 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 34037 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 34037 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 34037 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 34037 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 34037 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 34037 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 34037 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 34055 R-BTA-6799722 https://reactome.org/PathwayBrowser/#/R-BTA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Bos taurus 34055 R-CFA-6799722 https://reactome.org/PathwayBrowser/#/R-CFA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Canis familiaris 34055 R-DDI-6799722 https://reactome.org/PathwayBrowser/#/R-DDI-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Dictyostelium discoideum 34055 R-GGA-6799722 https://reactome.org/PathwayBrowser/#/R-GGA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Gallus gallus 34055 R-HSA-6799722 https://reactome.org/PathwayBrowser/#/R-HSA-6799722 TP53I3 oxidoreductase generates unstable semiquinones TAS Homo sapiens 34055 R-HSA-6799733 https://reactome.org/PathwayBrowser/#/R-HSA-6799733 Semiquinone reacts with oxygen TAS Homo sapiens 34055 R-SSC-6799722 https://reactome.org/PathwayBrowser/#/R-SSC-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Sus scrofa 34055 R-XTR-6799722 https://reactome.org/PathwayBrowser/#/R-XTR-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Xenopus tropicalis 3410 R-BTA-5692283 https://reactome.org/PathwayBrowser/#/R-BTA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Bos taurus 3410 R-CEL-5692283 https://reactome.org/PathwayBrowser/#/R-CEL-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Caenorhabditis elegans 3410 R-CFA-5692283 https://reactome.org/PathwayBrowser/#/R-CFA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Canis familiaris 3410 R-DDI-5692283 https://reactome.org/PathwayBrowser/#/R-DDI-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Dictyostelium discoideum 3410 R-DME-5692283 https://reactome.org/PathwayBrowser/#/R-DME-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Drosophila melanogaster 3410 R-DRE-5692283 https://reactome.org/PathwayBrowser/#/R-DRE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Danio rerio 3410 R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus 3410 R-HSA-5692283 https://reactome.org/PathwayBrowser/#/R-HSA-5692283 ALD3A1 oxidises 4HPCP to CXPA TAS Homo sapiens 3410 R-MMU-5692283 https://reactome.org/PathwayBrowser/#/R-MMU-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Mus musculus 3410 R-RNO-5692283 https://reactome.org/PathwayBrowser/#/R-RNO-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Rattus norvegicus 3410 R-SCE-5692283 https://reactome.org/PathwayBrowser/#/R-SCE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Saccharomyces cerevisiae 3410 R-SSC-5692283 https://reactome.org/PathwayBrowser/#/R-SSC-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Sus scrofa 34130 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 34130 R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Bos taurus 34130 R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Bos taurus 34130 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 34130 R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Caenorhabditis elegans 34130 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 34130 R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Canis familiaris 34130 R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Canis familiaris 34130 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 34130 R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Dictyostelium discoideum 34130 R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Dictyostelium discoideum 34130 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 34130 R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Drosophila melanogaster 34130 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 34130 R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Danio rerio 34130 R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Danio rerio 34130 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 34130 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Gallus gallus 34130 R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Gallus gallus 34130 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 34130 R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) TAS Homo sapiens 34130 R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 TAS Homo sapiens 34130 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 34130 R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Mus musculus 34130 R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Mus musculus 34130 R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Plasmodium falciparum 34130 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 34130 R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Rattus norvegicus 34130 R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Rattus norvegicus 34130 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 34130 R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Sus scrofa 34130 R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Sus scrofa 34130 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 34130 R-XTR-2161899 https://reactome.org/PathwayBrowser/#/R-XTR-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Xenopus tropicalis 34130 R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Xenopus tropicalis 34144 R-BTA-2161959 https://reactome.org/PathwayBrowser/#/R-BTA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Bos taurus 34144 R-CEL-2161959 https://reactome.org/PathwayBrowser/#/R-CEL-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Caenorhabditis elegans 34144 R-CFA-2161959 https://reactome.org/PathwayBrowser/#/R-CFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Canis familiaris 34144 R-GGA-2161959 https://reactome.org/PathwayBrowser/#/R-GGA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Gallus gallus 34144 R-HSA-2161959 https://reactome.org/PathwayBrowser/#/R-HSA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 TAS Homo sapiens 34144 R-MMU-2161959 https://reactome.org/PathwayBrowser/#/R-MMU-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Mus musculus 34144 R-PFA-2161959 https://reactome.org/PathwayBrowser/#/R-PFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Plasmodium falciparum 34144 R-RNO-2161959 https://reactome.org/PathwayBrowser/#/R-RNO-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Rattus norvegicus 34144 R-SSC-2161959 https://reactome.org/PathwayBrowser/#/R-SSC-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Sus scrofa 34145 R-BTA-2161950 https://reactome.org/PathwayBrowser/#/R-BTA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Bos taurus 34145 R-BTA-2161959 https://reactome.org/PathwayBrowser/#/R-BTA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Bos taurus 34145 R-BTA-8942208 https://reactome.org/PathwayBrowser/#/R-BTA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Bos taurus 34145 R-CEL-2161959 https://reactome.org/PathwayBrowser/#/R-CEL-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Caenorhabditis elegans 34145 R-CFA-2161950 https://reactome.org/PathwayBrowser/#/R-CFA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Canis familiaris 34145 R-CFA-2161959 https://reactome.org/PathwayBrowser/#/R-CFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Canis familiaris 34145 R-CFA-8942208 https://reactome.org/PathwayBrowser/#/R-CFA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Canis familiaris 34145 R-DDI-2161950 https://reactome.org/PathwayBrowser/#/R-DDI-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Dictyostelium discoideum 34145 R-DDI-8942208 https://reactome.org/PathwayBrowser/#/R-DDI-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Dictyostelium discoideum 34145 R-DRE-2161950 https://reactome.org/PathwayBrowser/#/R-DRE-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Danio rerio 34145 R-DRE-8942208 https://reactome.org/PathwayBrowser/#/R-DRE-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Danio rerio 34145 R-GGA-2161950 https://reactome.org/PathwayBrowser/#/R-GGA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Gallus gallus 34145 R-GGA-2161959 https://reactome.org/PathwayBrowser/#/R-GGA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Gallus gallus 34145 R-GGA-8942208 https://reactome.org/PathwayBrowser/#/R-GGA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Gallus gallus 34145 R-HSA-2161950 https://reactome.org/PathwayBrowser/#/R-HSA-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B TAS Homo sapiens 34145 R-HSA-2161959 https://reactome.org/PathwayBrowser/#/R-HSA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 TAS Homo sapiens 34145 R-HSA-8942208 https://reactome.org/PathwayBrowser/#/R-HSA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 TAS Homo sapiens 34145 R-MMU-2161950 https://reactome.org/PathwayBrowser/#/R-MMU-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Mus musculus 34145 R-MMU-2161959 https://reactome.org/PathwayBrowser/#/R-MMU-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Mus musculus 34145 R-MMU-8942208 https://reactome.org/PathwayBrowser/#/R-MMU-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Mus musculus 34145 R-PFA-2161959 https://reactome.org/PathwayBrowser/#/R-PFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Plasmodium falciparum 34145 R-RNO-2161950 https://reactome.org/PathwayBrowser/#/R-RNO-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Rattus norvegicus 34145 R-RNO-2161959 https://reactome.org/PathwayBrowser/#/R-RNO-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Rattus norvegicus 34145 R-RNO-8942208 https://reactome.org/PathwayBrowser/#/R-RNO-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Rattus norvegicus 34145 R-SSC-2161950 https://reactome.org/PathwayBrowser/#/R-SSC-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Sus scrofa 34145 R-SSC-2161959 https://reactome.org/PathwayBrowser/#/R-SSC-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Sus scrofa 34145 R-SSC-8942208 https://reactome.org/PathwayBrowser/#/R-SSC-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Sus scrofa 34145 R-XTR-2161950 https://reactome.org/PathwayBrowser/#/R-XTR-2161950 Arachidonic acid is oxidised to 12R-HpETE by ALOX12B IEA Xenopus tropicalis 34145 R-XTR-8942208 https://reactome.org/PathwayBrowser/#/R-XTR-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Xenopus tropicalis 34146 R-BTA-2161999 https://reactome.org/PathwayBrowser/#/R-BTA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Bos taurus 34146 R-BTA-3296304 https://reactome.org/PathwayBrowser/#/R-BTA-3296304 GPR31 is a receptor for 12(S)-HETE IEA Bos taurus 34146 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 34146 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 34146 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 34146 R-CEL-2161999 https://reactome.org/PathwayBrowser/#/R-CEL-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Caenorhabditis elegans 34146 R-CFA-2161999 https://reactome.org/PathwayBrowser/#/R-CFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Canis familiaris 34146 R-CFA-3296304 https://reactome.org/PathwayBrowser/#/R-CFA-3296304 GPR31 is a receptor for 12(S)-HETE IEA Canis familiaris 34146 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 34146 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 34146 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 34146 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 34146 R-GGA-2161999 https://reactome.org/PathwayBrowser/#/R-GGA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Gallus gallus 34146 R-HSA-2161999 https://reactome.org/PathwayBrowser/#/R-HSA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 TAS Homo sapiens 34146 R-HSA-3296304 https://reactome.org/PathwayBrowser/#/R-HSA-3296304 GPR31 is a receptor for 12(S)-HETE TAS Homo sapiens 34146 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 34146 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 34146 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 34146 R-MMU-2161999 https://reactome.org/PathwayBrowser/#/R-MMU-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Mus musculus 34146 R-MMU-3296304 https://reactome.org/PathwayBrowser/#/R-MMU-3296304 GPR31 is a receptor for 12(S)-HETE IEA Mus musculus 34146 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 34146 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 34146 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 34146 R-PFA-2161999 https://reactome.org/PathwayBrowser/#/R-PFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Plasmodium falciparum 34146 R-RNO-2161999 https://reactome.org/PathwayBrowser/#/R-RNO-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Rattus norvegicus 34146 R-SSC-2161999 https://reactome.org/PathwayBrowser/#/R-SSC-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Sus scrofa 34146 R-SSC-3296304 https://reactome.org/PathwayBrowser/#/R-SSC-3296304 GPR31 is a receptor for 12(S)-HETE IEA Sus scrofa 34146 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 34146 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 34146 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 34151 R-BTA-2161948 https://reactome.org/PathwayBrowser/#/R-BTA-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Bos taurus 34151 R-CFA-2161948 https://reactome.org/PathwayBrowser/#/R-CFA-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Canis familiaris 34151 R-DDI-2161948 https://reactome.org/PathwayBrowser/#/R-DDI-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Dictyostelium discoideum 34151 R-DRE-2161948 https://reactome.org/PathwayBrowser/#/R-DRE-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Danio rerio 34151 R-HSA-2161948 https://reactome.org/PathwayBrowser/#/R-HSA-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 TAS Homo sapiens 34151 R-MMU-2161948 https://reactome.org/PathwayBrowser/#/R-MMU-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Mus musculus 34151 R-RNO-2161948 https://reactome.org/PathwayBrowser/#/R-RNO-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Rattus norvegicus 34151 R-SSC-2161948 https://reactome.org/PathwayBrowser/#/R-SSC-2161948 Arachidonic acid is converted to 12-oxoETE by ALOX12 IEA Sus scrofa 34154 R-HSA-1183003 https://reactome.org/PathwayBrowser/#/R-HSA-1183003 Expression of Leptin TAS Homo sapiens 34154 R-HSA-1183058 https://reactome.org/PathwayBrowser/#/R-HSA-1183058 Expression of Adiponectin TAS Homo sapiens 34154 R-HSA-381309 https://reactome.org/PathwayBrowser/#/R-HSA-381309 PPARG:RXRA heterodimer binds to fatty acid-like ligands IEA Homo sapiens 34154 R-HSA-560472 https://reactome.org/PathwayBrowser/#/R-HSA-560472 Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) TAS Homo sapiens 34154 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 34154 R-HSA-560491 https://reactome.org/PathwayBrowser/#/R-HSA-560491 Expression of CEBPA IEA Homo sapiens 34154 R-HSA-560493 https://reactome.org/PathwayBrowser/#/R-HSA-560493 Expression of Perilipin (PLIN) TAS Homo sapiens 34154 R-HSA-560498 https://reactome.org/PathwayBrowser/#/R-HSA-560498 Expression of Lipoprotein lipase (LPL) TAS Homo sapiens 34154 R-HSA-560510 https://reactome.org/PathwayBrowser/#/R-HSA-560510 Expression of FABP4 (aP2) TAS Homo sapiens 34154 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 34154 R-HSA-8944099 https://reactome.org/PathwayBrowser/#/R-HSA-8944099 Activated PPARG binds PTEN gene promoter TAS Homo sapiens 34154 R-HSA-8944104 https://reactome.org/PathwayBrowser/#/R-HSA-8944104 PTEN gene transcription is stimulated by TP53, EGR1, PPARG, ATF2, MAF1, and inhibited by NR2E1, SALL4, MECOM, SNAI1, SNAI2, JUN IEA Homo sapiens 34154 R-HSA-9844415 https://reactome.org/PathwayBrowser/#/R-HSA-9844415 PRDM16 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 IEA Homo sapiens 34154 R-HSA-9844440 https://reactome.org/PathwayBrowser/#/R-HSA-9844440 PPARG binds EBF2-bound gene loci IEA Homo sapiens 34154 R-HSA-9844536 https://reactome.org/PathwayBrowser/#/R-HSA-9844536 PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 34154 R-HSA-9844549 https://reactome.org/PathwayBrowser/#/R-HSA-9844549 UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 34154 R-HSA-9844600 https://reactome.org/PathwayBrowser/#/R-HSA-9844600 CIDEA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 34154 R-HSA-9844822 https://reactome.org/PathwayBrowser/#/R-HSA-9844822 PPARGC1A gene expression is stimulated by EBF2 IEA Homo sapiens 34154 R-MMU-556760 https://reactome.org/PathwayBrowser/#/R-MMU-556760 Pparg:Rxra heterodimer binds to fatty acids TAS Mus musculus 34154 R-MMU-9844541 https://reactome.org/PathwayBrowser/#/R-MMU-9844541 Ppara gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 34154 R-MMU-9844554 https://reactome.org/PathwayBrowser/#/R-MMU-9844554 Ucp1 gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 34154 R-MMU-9844626 https://reactome.org/PathwayBrowser/#/R-MMU-9844626 Cidea gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 34154 R-MMU-9844655 https://reactome.org/PathwayBrowser/#/R-MMU-9844655 Dio2 gene expression is stimulated by Ebf2 and repressed by Znf423 and NuRD TAS Mus musculus 34154 R-MMU-9844700 https://reactome.org/PathwayBrowser/#/R-MMU-9844700 Pparg binds Ebf2-bound gene loci TAS Mus musculus 34154 R-MMU-9844775 https://reactome.org/PathwayBrowser/#/R-MMU-9844775 Prdm16 gene expression is stimulated by Ebf2 and Pparg and inhibited by Znf423 TAS Mus musculus 34154 R-MMU-9844841 https://reactome.org/PathwayBrowser/#/R-MMU-9844841 Ppargc1a gene expression is positively regulated by Ebf2 and Pparg TAS Mus musculus 34157 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 34157 R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Bos taurus 34157 R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Bos taurus 34157 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 34157 R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Caenorhabditis elegans 34157 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 34157 R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Canis familiaris 34157 R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Canis familiaris 34157 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 34157 R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Dictyostelium discoideum 34157 R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Dictyostelium discoideum 34157 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 34157 R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Drosophila melanogaster 34157 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 34157 R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Danio rerio 34157 R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Danio rerio 34157 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 34157 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Gallus gallus 34157 R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Gallus gallus 34157 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 34157 R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) TAS Homo sapiens 34157 R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 TAS Homo sapiens 34157 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 34157 R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Mus musculus 34157 R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Mus musculus 34157 R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Plasmodium falciparum 34157 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 34157 R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Rattus norvegicus 34157 R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Rattus norvegicus 34157 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 34157 R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Sus scrofa 34157 R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Sus scrofa 34157 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 34157 R-XTR-2161899 https://reactome.org/PathwayBrowser/#/R-XTR-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Xenopus tropicalis 34157 R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Xenopus tropicalis 34159 R-HSA-2161588 https://reactome.org/PathwayBrowser/#/R-HSA-2161588 Delta12-PGJ2 is dehydrated to 15d-PGJ2 TAS Homo sapiens 34159 R-HSA-9844415 https://reactome.org/PathwayBrowser/#/R-HSA-9844415 PRDM16 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 IEA Homo sapiens 34159 R-HSA-9844440 https://reactome.org/PathwayBrowser/#/R-HSA-9844440 PPARG binds EBF2-bound gene loci IEA Homo sapiens 34159 R-HSA-9844536 https://reactome.org/PathwayBrowser/#/R-HSA-9844536 PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 34159 R-HSA-9844549 https://reactome.org/PathwayBrowser/#/R-HSA-9844549 UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 34159 R-HSA-9844600 https://reactome.org/PathwayBrowser/#/R-HSA-9844600 CIDEA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 34159 R-HSA-9844822 https://reactome.org/PathwayBrowser/#/R-HSA-9844822 PPARGC1A gene expression is stimulated by EBF2 IEA Homo sapiens 34159 R-MMU-9844541 https://reactome.org/PathwayBrowser/#/R-MMU-9844541 Ppara gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 34159 R-MMU-9844554 https://reactome.org/PathwayBrowser/#/R-MMU-9844554 Ucp1 gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 34159 R-MMU-9844626 https://reactome.org/PathwayBrowser/#/R-MMU-9844626 Cidea gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 34159 R-MMU-9844655 https://reactome.org/PathwayBrowser/#/R-MMU-9844655 Dio2 gene expression is stimulated by Ebf2 and repressed by Znf423 and NuRD TAS Mus musculus 34159 R-MMU-9844700 https://reactome.org/PathwayBrowser/#/R-MMU-9844700 Pparg binds Ebf2-bound gene loci TAS Mus musculus 34159 R-MMU-9844775 https://reactome.org/PathwayBrowser/#/R-MMU-9844775 Prdm16 gene expression is stimulated by Ebf2 and Pparg and inhibited by Znf423 TAS Mus musculus 34159 R-MMU-9844841 https://reactome.org/PathwayBrowser/#/R-MMU-9844841 Ppargc1a gene expression is positively regulated by Ebf2 and Pparg TAS Mus musculus 3419 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 3419 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 3419 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 3419 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 3419 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 3419 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 3419 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 3419 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 3419 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 3419 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 34306 R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 34306 R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 34306 R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 34306 R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 34306 R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 34306 R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 34306 R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 34306 R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 34306 R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa 34306 R-XTR-2161940 https://reactome.org/PathwayBrowser/#/R-XTR-2161940 Arachidonic acid is hydroxylated to 20-HETE by CYP(3) IEA Xenopus tropicalis 34310 R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 34310 R-BTA-192178 https://reactome.org/PathwayBrowser/#/R-BTA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Bos taurus 34310 R-BTA-4720432 https://reactome.org/PathwayBrowser/#/R-BTA-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Bos taurus 34310 R-BTA-4720446 https://reactome.org/PathwayBrowser/#/R-BTA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Bos taurus 34310 R-BTA-9024326 https://reactome.org/PathwayBrowser/#/R-BTA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Bos taurus 34310 R-BTA-9024334 https://reactome.org/PathwayBrowser/#/R-BTA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Bos taurus 34310 R-BTA-9029517 https://reactome.org/PathwayBrowser/#/R-BTA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Bos taurus 34310 R-BTA-9029551 https://reactome.org/PathwayBrowser/#/R-BTA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Bos taurus 34310 R-BTA-9029561 https://reactome.org/PathwayBrowser/#/R-BTA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Bos taurus 34310 R-BTA-9029566 https://reactome.org/PathwayBrowser/#/R-BTA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Bos taurus 34310 R-BTA-9029580 https://reactome.org/PathwayBrowser/#/R-BTA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Bos taurus 34310 R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 34310 R-CFA-192178 https://reactome.org/PathwayBrowser/#/R-CFA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Canis familiaris 34310 R-CFA-9024326 https://reactome.org/PathwayBrowser/#/R-CFA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Canis familiaris 34310 R-CFA-9024334 https://reactome.org/PathwayBrowser/#/R-CFA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Canis familiaris 34310 R-CFA-9029517 https://reactome.org/PathwayBrowser/#/R-CFA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Canis familiaris 34310 R-CFA-9029551 https://reactome.org/PathwayBrowser/#/R-CFA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Canis familiaris 34310 R-CFA-9029561 https://reactome.org/PathwayBrowser/#/R-CFA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Canis familiaris 34310 R-CFA-9029566 https://reactome.org/PathwayBrowser/#/R-CFA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Canis familiaris 34310 R-CFA-9029580 https://reactome.org/PathwayBrowser/#/R-CFA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Canis familiaris 34310 R-DME-4720432 https://reactome.org/PathwayBrowser/#/R-DME-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Drosophila melanogaster 34310 R-DME-4720446 https://reactome.org/PathwayBrowser/#/R-DME-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Drosophila melanogaster 34310 R-DME-9024326 https://reactome.org/PathwayBrowser/#/R-DME-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Drosophila melanogaster 34310 R-DME-9024334 https://reactome.org/PathwayBrowser/#/R-DME-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Drosophila melanogaster 34310 R-DME-9029517 https://reactome.org/PathwayBrowser/#/R-DME-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Drosophila melanogaster 34310 R-DME-9029551 https://reactome.org/PathwayBrowser/#/R-DME-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Drosophila melanogaster 34310 R-DME-9029561 https://reactome.org/PathwayBrowser/#/R-DME-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Drosophila melanogaster 34310 R-DME-9029566 https://reactome.org/PathwayBrowser/#/R-DME-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Drosophila melanogaster 34310 R-DME-9029580 https://reactome.org/PathwayBrowser/#/R-DME-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Drosophila melanogaster 34310 R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 34310 R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 34310 R-GGA-192178 https://reactome.org/PathwayBrowser/#/R-GGA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Gallus gallus 34310 R-GGA-4720446 https://reactome.org/PathwayBrowser/#/R-GGA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Gallus gallus 34310 R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 34310 R-HSA-192178 https://reactome.org/PathwayBrowser/#/R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL TAS Homo sapiens 34310 R-HSA-193767 https://reactome.org/PathwayBrowser/#/R-HSA-193767 Influx of 24-hydroxycholesterol TAS Homo sapiens 34310 R-HSA-193776 https://reactome.org/PathwayBrowser/#/R-HSA-193776 Efflux of 24-hydroxycholesterol TAS Homo sapiens 34310 R-HSA-4720432 https://reactome.org/PathwayBrowser/#/R-HSA-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 TAS Homo sapiens 34310 R-HSA-4720446 https://reactome.org/PathwayBrowser/#/R-HSA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 TAS Homo sapiens 34310 R-HSA-9024326 https://reactome.org/PathwayBrowser/#/R-HSA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex TAS Homo sapiens 34310 R-HSA-9024334 https://reactome.org/PathwayBrowser/#/R-HSA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene TAS Homo sapiens 34310 R-HSA-9024361 https://reactome.org/PathwayBrowser/#/R-HSA-9024361 Expression of ABCG1 regulated by NR1H2,3 TAS Homo sapiens 34310 R-HSA-9024386 https://reactome.org/PathwayBrowser/#/R-HSA-9024386 Oxysterol-induced binding of NR1H2,3:RXR to the ABCG1 gene TAS Homo sapiens 34310 R-HSA-9028524 https://reactome.org/PathwayBrowser/#/R-HSA-9028524 NR1H3, NRIP1 bind the PCK1 gene TAS Homo sapiens 34310 R-HSA-9028525 https://reactome.org/PathwayBrowser/#/R-HSA-9028525 NR1H2 or NR1H3, NRIP1 bind the SREBF1 gene TAS Homo sapiens 34310 R-HSA-9028526 https://reactome.org/PathwayBrowser/#/R-HSA-9028526 NR1H2 or NR1H3, NRIP1 bind the SCD gene TAS Homo sapiens 34310 R-HSA-9028533 https://reactome.org/PathwayBrowser/#/R-HSA-9028533 NR1H2,3, NRIP1 bind the FASN gene TAS Homo sapiens 34310 R-HSA-9029517 https://reactome.org/PathwayBrowser/#/R-HSA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex TAS Homo sapiens 34310 R-HSA-9029521 https://reactome.org/PathwayBrowser/#/R-HSA-9029521 NR1H2,3 binds the ABCG5 gene TAS Homo sapiens 34310 R-HSA-9029531 https://reactome.org/PathwayBrowser/#/R-HSA-9029531 Expression of ABCG5 regulated by NR1H2,3 TAS Homo sapiens 34310 R-HSA-9029536 https://reactome.org/PathwayBrowser/#/R-HSA-9029536 Expression of UGT1A3 TAS Homo sapiens 34310 R-HSA-9029551 https://reactome.org/PathwayBrowser/#/R-HSA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex TAS Homo sapiens 34310 R-HSA-9029555 https://reactome.org/PathwayBrowser/#/R-HSA-9029555 NR1H2,3 binds the ABCG8 gene TAS Homo sapiens 34310 R-HSA-9029561 https://reactome.org/PathwayBrowser/#/R-HSA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter TAS Homo sapiens 34310 R-HSA-9029566 https://reactome.org/PathwayBrowser/#/R-HSA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene TAS Homo sapiens 34310 R-HSA-9029580 https://reactome.org/PathwayBrowser/#/R-HSA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex TAS Homo sapiens 34310 R-HSA-9029591 https://reactome.org/PathwayBrowser/#/R-HSA-9029591 Expression of ABCG8 regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9031510 https://reactome.org/PathwayBrowser/#/R-HSA-9031510 Expression of APOC1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9031512 https://reactome.org/PathwayBrowser/#/R-HSA-9031512 Expression of APOE regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9031518 https://reactome.org/PathwayBrowser/#/R-HSA-9031518 NR1H2,3 binds the APOC1 gene TAS Homo sapiens 34310 R-HSA-9031521 https://reactome.org/PathwayBrowser/#/R-HSA-9031521 NR1H2,3 binds the APOC2 gene TAS Homo sapiens 34310 R-HSA-9031522 https://reactome.org/PathwayBrowser/#/R-HSA-9031522 NR1H2,3 binds the APOE gene TAS Homo sapiens 34310 R-HSA-9031527 https://reactome.org/PathwayBrowser/#/R-HSA-9031527 Expression of APOC2 regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9035133 https://reactome.org/PathwayBrowser/#/R-HSA-9035133 NR1H2,3 binds the CETP gene TAS Homo sapiens 34310 R-HSA-9035143 https://reactome.org/PathwayBrowser/#/R-HSA-9035143 NR1H2,3 binds the APOC4 gene TAS Homo sapiens 34310 R-HSA-9035167 https://reactome.org/PathwayBrowser/#/R-HSA-9035167 NR1H2,3 binds the EEPD1 gene TAS Homo sapiens 34310 R-HSA-9035169 https://reactome.org/PathwayBrowser/#/R-HSA-9035169 Expression of CETP regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9035180 https://reactome.org/PathwayBrowser/#/R-HSA-9035180 Expression of EEPD1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9035185 https://reactome.org/PathwayBrowser/#/R-HSA-9035185 NR1H2,3 binds the NR1H3 gene TAS Homo sapiens 34310 R-HSA-9035279 https://reactome.org/PathwayBrowser/#/R-HSA-9035279 Expression of APOC4 regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9035281 https://reactome.org/PathwayBrowser/#/R-HSA-9035281 NR1H3 gene transcription regulated by NR1H2,3 TAS Homo sapiens 34310 R-HSA-9605051 https://reactome.org/PathwayBrowser/#/R-HSA-9605051 Expression of PCK1 regulated by NR1H3 TAS Homo sapiens 34310 R-HSA-9605056 https://reactome.org/PathwayBrowser/#/R-HSA-9605056 Expression of SREBF1 (SREBP1) regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9605057 https://reactome.org/PathwayBrowser/#/R-HSA-9605057 ABCA1 gene transcription regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9605060 https://reactome.org/PathwayBrowser/#/R-HSA-9605060 Expression of SCD regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9605063 https://reactome.org/PathwayBrowser/#/R-HSA-9605063 Expression of FASN regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9607342 https://reactome.org/PathwayBrowser/#/R-HSA-9607342 Expression of FABP6 regulated by NR1H2,3 TAS Homo sapiens 34310 R-HSA-9608039 https://reactome.org/PathwayBrowser/#/R-HSA-9608039 NR1H2,3 binds the PLIN1 gene TAS Homo sapiens 34310 R-HSA-9608048 https://reactome.org/PathwayBrowser/#/R-HSA-9608048 Expression of PLIN1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9618394 https://reactome.org/PathwayBrowser/#/R-HSA-9618394 ARL4C gene transcription regulated by NR1H2,3 TAS Homo sapiens 34310 R-HSA-9618407 https://reactome.org/PathwayBrowser/#/R-HSA-9618407 NR1H2,3 binds the ARL4C gene TAS Homo sapiens 34310 R-HSA-9623365 https://reactome.org/PathwayBrowser/#/R-HSA-9623365 Expression of MYLIP regulated by NR1H2,3 TAS Homo sapiens 34310 R-HSA-9623366 https://reactome.org/PathwayBrowser/#/R-HSA-9623366 NR1H2,3 binds the MYLIP gene TAS Homo sapiens 34310 R-HSA-9624353 https://reactome.org/PathwayBrowser/#/R-HSA-9624353 NR1H2,3 binds the PLTP gene TAS Homo sapiens 34310 R-HSA-9624365 https://reactome.org/PathwayBrowser/#/R-HSA-9624365 Expression of PLTP regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9631296 https://reactome.org/PathwayBrowser/#/R-HSA-9631296 NR1H2,3 binds the FABP6 gene TAS Homo sapiens 34310 R-HSA-9657767 https://reactome.org/PathwayBrowser/#/R-HSA-9657767 Expression of APOD regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9657775 https://reactome.org/PathwayBrowser/#/R-HSA-9657775 Expression of ANGPTL3 regulated by NR1H2 or NR1H3 TAS Homo sapiens 34310 R-HSA-9657786 https://reactome.org/PathwayBrowser/#/R-HSA-9657786 NR1H2,3 binds the APOD gene TAS Homo sapiens 34310 R-HSA-9657836 https://reactome.org/PathwayBrowser/#/R-HSA-9657836 NR1H2,3 binds the ANGPTL3 gene TAS Homo sapiens 34310 R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 34310 R-MMU-192178 https://reactome.org/PathwayBrowser/#/R-MMU-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Mus musculus 34310 R-MMU-4720432 https://reactome.org/PathwayBrowser/#/R-MMU-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Mus musculus 34310 R-MMU-4720446 https://reactome.org/PathwayBrowser/#/R-MMU-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Mus musculus 34310 R-MMU-9024326 https://reactome.org/PathwayBrowser/#/R-MMU-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Mus musculus 34310 R-MMU-9024334 https://reactome.org/PathwayBrowser/#/R-MMU-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Mus musculus 34310 R-MMU-9029517 https://reactome.org/PathwayBrowser/#/R-MMU-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Mus musculus 34310 R-MMU-9029551 https://reactome.org/PathwayBrowser/#/R-MMU-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Mus musculus 34310 R-MMU-9029561 https://reactome.org/PathwayBrowser/#/R-MMU-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Mus musculus 34310 R-MMU-9029566 https://reactome.org/PathwayBrowser/#/R-MMU-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Mus musculus 34310 R-MMU-9029580 https://reactome.org/PathwayBrowser/#/R-MMU-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Mus musculus 34310 R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 34310 R-RNO-192178 https://reactome.org/PathwayBrowser/#/R-RNO-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Rattus norvegicus 34310 R-RNO-4720432 https://reactome.org/PathwayBrowser/#/R-RNO-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Rattus norvegicus 34310 R-RNO-4720446 https://reactome.org/PathwayBrowser/#/R-RNO-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Rattus norvegicus 34310 R-RNO-9024326 https://reactome.org/PathwayBrowser/#/R-RNO-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Rattus norvegicus 34310 R-RNO-9024334 https://reactome.org/PathwayBrowser/#/R-RNO-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Rattus norvegicus 34310 R-RNO-9029517 https://reactome.org/PathwayBrowser/#/R-RNO-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Rattus norvegicus 34310 R-RNO-9029551 https://reactome.org/PathwayBrowser/#/R-RNO-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Rattus norvegicus 34310 R-RNO-9029561 https://reactome.org/PathwayBrowser/#/R-RNO-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Rattus norvegicus 34310 R-RNO-9029566 https://reactome.org/PathwayBrowser/#/R-RNO-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Rattus norvegicus 34310 R-RNO-9029580 https://reactome.org/PathwayBrowser/#/R-RNO-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Rattus norvegicus 34310 R-SSC-192061 https://reactome.org/PathwayBrowser/#/R-SSC-192061 CYP46A1 24-hydroxylates CHOL IEA Sus scrofa 34310 R-SSC-192178 https://reactome.org/PathwayBrowser/#/R-SSC-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Sus scrofa 34310 R-SSC-4720432 https://reactome.org/PathwayBrowser/#/R-SSC-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Sus scrofa 34310 R-SSC-4720446 https://reactome.org/PathwayBrowser/#/R-SSC-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Sus scrofa 34310 R-SSC-9024326 https://reactome.org/PathwayBrowser/#/R-SSC-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Sus scrofa 34310 R-SSC-9024334 https://reactome.org/PathwayBrowser/#/R-SSC-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Sus scrofa 34310 R-SSC-9029517 https://reactome.org/PathwayBrowser/#/R-SSC-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Sus scrofa 34310 R-SSC-9029551 https://reactome.org/PathwayBrowser/#/R-SSC-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Sus scrofa 34310 R-SSC-9029561 https://reactome.org/PathwayBrowser/#/R-SSC-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Sus scrofa 34310 R-SSC-9029566 https://reactome.org/PathwayBrowser/#/R-SSC-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Sus scrofa 34310 R-SSC-9029580 https://reactome.org/PathwayBrowser/#/R-SSC-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Sus scrofa 34310 R-XTR-192061 https://reactome.org/PathwayBrowser/#/R-XTR-192061 CYP46A1 24-hydroxylates CHOL IEA Xenopus tropicalis 34310 R-XTR-192178 https://reactome.org/PathwayBrowser/#/R-XTR-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Xenopus tropicalis 34310 R-XTR-9024326 https://reactome.org/PathwayBrowser/#/R-XTR-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Xenopus tropicalis 34310 R-XTR-9024334 https://reactome.org/PathwayBrowser/#/R-XTR-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Xenopus tropicalis 34310 R-XTR-9029517 https://reactome.org/PathwayBrowser/#/R-XTR-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Xenopus tropicalis 34310 R-XTR-9029566 https://reactome.org/PathwayBrowser/#/R-XTR-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Xenopus tropicalis 3435 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 3435 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 3435 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 3435 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 3435 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 3435 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 3435 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 3441 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 3441 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 3441 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 3441 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 3441 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 3441 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 3441 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 3441 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 3441 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 3441 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 3441 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 3441 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 3441 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 3441 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 3441 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 3441 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 3441 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 3441 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 3441 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 3441 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 3441 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 3441 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 3441 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 3441 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 3441 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 3441 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 3441 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 3441 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 3441 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 3441 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 3441 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 3441 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 3441 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 3441 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 3441 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 3441 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 3441 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 3445 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 3445 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 3445 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 3445 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 3445 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 3445 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 3445 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 3445 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 3445 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 3445 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 3445 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 3445 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 3445 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 3445 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 3445 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 3445 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 3445 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 3445 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 3445 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 3445 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 3445 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 3445 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 3445 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 3445 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 3445 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 3445 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 3445 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 3445 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 3445 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 3445 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 3445 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 3445 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 3445 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 3445 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 3445 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 3445 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 3445 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 3445 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 3445 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 3445 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 3445 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 3445 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 34450 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 34450 R-BTA-2161890 https://reactome.org/PathwayBrowser/#/R-BTA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Bos taurus 34450 R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Bos taurus 34450 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 34450 R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans 34450 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 34450 R-CFA-2161890 https://reactome.org/PathwayBrowser/#/R-CFA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Canis familiaris 34450 R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Canis familiaris 34450 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 34450 R-DDI-2161890 https://reactome.org/PathwayBrowser/#/R-DDI-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Dictyostelium discoideum 34450 R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Dictyostelium discoideum 34450 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 34450 R-DME-2161890 https://reactome.org/PathwayBrowser/#/R-DME-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Drosophila melanogaster 34450 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 34450 R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio 34450 R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Danio rerio 34450 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 34450 R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus 34450 R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Gallus gallus 34450 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 34450 R-HSA-2161890 https://reactome.org/PathwayBrowser/#/R-HSA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) TAS Homo sapiens 34450 R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 TAS Homo sapiens 34450 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 34450 R-MMU-2161890 https://reactome.org/PathwayBrowser/#/R-MMU-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Mus musculus 34450 R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Mus musculus 34450 R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Plasmodium falciparum 34450 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 34450 R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus 34450 R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Rattus norvegicus 34450 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 34450 R-SSC-2161890 https://reactome.org/PathwayBrowser/#/R-SSC-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Sus scrofa 34450 R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Sus scrofa 34450 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 34450 R-XTR-2161890 https://reactome.org/PathwayBrowser/#/R-XTR-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Xenopus tropicalis 34450 R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Xenopus tropicalis 34477 R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 34477 R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 34477 R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 34477 R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 34477 R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 34477 R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 34477 R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 34477 R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 34477 R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 34477 R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 34477 R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 34477 R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 34477 R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 34477 R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 34477 R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 34477 R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 34477 R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 34477 R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 34479 R-BTA-176054 https://reactome.org/PathwayBrowser/#/R-BTA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Bos taurus 34479 R-CEL-176054 https://reactome.org/PathwayBrowser/#/R-CEL-176054 GST dimers conjugate GSH with cytosolic substrates IEA Caenorhabditis elegans 34479 R-CFA-176054 https://reactome.org/PathwayBrowser/#/R-CFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Canis familiaris 34479 R-DDI-176054 https://reactome.org/PathwayBrowser/#/R-DDI-176054 GST dimers conjugate GSH with cytosolic substrates IEA Dictyostelium discoideum 34479 R-DME-176054 https://reactome.org/PathwayBrowser/#/R-DME-176054 GST dimers conjugate GSH with cytosolic substrates IEA Drosophila melanogaster 34479 R-DRE-176054 https://reactome.org/PathwayBrowser/#/R-DRE-176054 GST dimers conjugate GSH with cytosolic substrates IEA Danio rerio 34479 R-GGA-176054 https://reactome.org/PathwayBrowser/#/R-GGA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Gallus gallus 34479 R-HSA-176054 https://reactome.org/PathwayBrowser/#/R-HSA-176054 GST dimers conjugate GSH with cytosolic substrates TAS Homo sapiens 34479 R-MMU-176054 https://reactome.org/PathwayBrowser/#/R-MMU-176054 GST dimers conjugate GSH with cytosolic substrates IEA Mus musculus 34479 R-PFA-176054 https://reactome.org/PathwayBrowser/#/R-PFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Plasmodium falciparum 34479 R-RNO-176054 https://reactome.org/PathwayBrowser/#/R-RNO-176054 GST dimers conjugate GSH with cytosolic substrates IEA Rattus norvegicus 34479 R-SSC-176054 https://reactome.org/PathwayBrowser/#/R-SSC-176054 GST dimers conjugate GSH with cytosolic substrates IEA Sus scrofa 34479 R-XTR-176054 https://reactome.org/PathwayBrowser/#/R-XTR-176054 GST dimers conjugate GSH with cytosolic substrates IEA Xenopus tropicalis 34490 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 34490 R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Bos taurus 34490 R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Bos taurus 34490 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 34490 R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Caenorhabditis elegans 34490 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 34490 R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Canis familiaris 34490 R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Canis familiaris 34490 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 34490 R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Dictyostelium discoideum 34490 R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Dictyostelium discoideum 34490 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 34490 R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Drosophila melanogaster 34490 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 34490 R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Danio rerio 34490 R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Danio rerio 34490 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 34490 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Gallus gallus 34490 R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Gallus gallus 34490 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 34490 R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) TAS Homo sapiens 34490 R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 TAS Homo sapiens 34490 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 34490 R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Mus musculus 34490 R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Mus musculus 34490 R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Plasmodium falciparum 34490 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 34490 R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Rattus norvegicus 34490 R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Rattus norvegicus 34490 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 34490 R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Sus scrofa 34490 R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Sus scrofa 34490 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 34490 R-XTR-2161899 https://reactome.org/PathwayBrowser/#/R-XTR-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Xenopus tropicalis 34490 R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Xenopus tropicalis 34496 R-HSA-1183003 https://reactome.org/PathwayBrowser/#/R-HSA-1183003 Expression of Leptin TAS Homo sapiens 34496 R-HSA-1183058 https://reactome.org/PathwayBrowser/#/R-HSA-1183058 Expression of Adiponectin TAS Homo sapiens 34496 R-HSA-381309 https://reactome.org/PathwayBrowser/#/R-HSA-381309 PPARG:RXRA heterodimer binds to fatty acid-like ligands IEA Homo sapiens 34496 R-HSA-560472 https://reactome.org/PathwayBrowser/#/R-HSA-560472 Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) TAS Homo sapiens 34496 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 34496 R-HSA-560491 https://reactome.org/PathwayBrowser/#/R-HSA-560491 Expression of CEBPA IEA Homo sapiens 34496 R-HSA-560493 https://reactome.org/PathwayBrowser/#/R-HSA-560493 Expression of Perilipin (PLIN) TAS Homo sapiens 34496 R-HSA-560498 https://reactome.org/PathwayBrowser/#/R-HSA-560498 Expression of Lipoprotein lipase (LPL) TAS Homo sapiens 34496 R-HSA-560510 https://reactome.org/PathwayBrowser/#/R-HSA-560510 Expression of FABP4 (aP2) TAS Homo sapiens 34496 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 34496 R-HSA-8944099 https://reactome.org/PathwayBrowser/#/R-HSA-8944099 Activated PPARG binds PTEN gene promoter TAS Homo sapiens 34496 R-HSA-8944104 https://reactome.org/PathwayBrowser/#/R-HSA-8944104 PTEN gene transcription is stimulated by TP53, EGR1, PPARG, ATF2, MAF1, and inhibited by NR2E1, SALL4, MECOM, SNAI1, SNAI2, JUN IEA Homo sapiens 34496 R-HSA-9844415 https://reactome.org/PathwayBrowser/#/R-HSA-9844415 PRDM16 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 IEA Homo sapiens 34496 R-HSA-9844440 https://reactome.org/PathwayBrowser/#/R-HSA-9844440 PPARG binds EBF2-bound gene loci IEA Homo sapiens 34496 R-HSA-9844536 https://reactome.org/PathwayBrowser/#/R-HSA-9844536 PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 34496 R-HSA-9844549 https://reactome.org/PathwayBrowser/#/R-HSA-9844549 UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 34496 R-HSA-9844600 https://reactome.org/PathwayBrowser/#/R-HSA-9844600 CIDEA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 34496 R-HSA-9844822 https://reactome.org/PathwayBrowser/#/R-HSA-9844822 PPARGC1A gene expression is stimulated by EBF2 IEA Homo sapiens 34496 R-MMU-556760 https://reactome.org/PathwayBrowser/#/R-MMU-556760 Pparg:Rxra heterodimer binds to fatty acids TAS Mus musculus 34496 R-MMU-9844541 https://reactome.org/PathwayBrowser/#/R-MMU-9844541 Ppara gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 34496 R-MMU-9844554 https://reactome.org/PathwayBrowser/#/R-MMU-9844554 Ucp1 gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 34496 R-MMU-9844626 https://reactome.org/PathwayBrowser/#/R-MMU-9844626 Cidea gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 34496 R-MMU-9844655 https://reactome.org/PathwayBrowser/#/R-MMU-9844655 Dio2 gene expression is stimulated by Ebf2 and repressed by Znf423 and NuRD TAS Mus musculus 34496 R-MMU-9844700 https://reactome.org/PathwayBrowser/#/R-MMU-9844700 Pparg binds Ebf2-bound gene loci TAS Mus musculus 34496 R-MMU-9844775 https://reactome.org/PathwayBrowser/#/R-MMU-9844775 Prdm16 gene expression is stimulated by Ebf2 and Pparg and inhibited by Znf423 TAS Mus musculus 34496 R-MMU-9844841 https://reactome.org/PathwayBrowser/#/R-MMU-9844841 Ppargc1a gene expression is positively regulated by Ebf2 and Pparg TAS Mus musculus 34507 R-BTA-9659611 https://reactome.org/PathwayBrowser/#/R-BTA-9659611 ANO1 inhibitors bind ANO1 IEA Bos taurus 34507 R-CFA-9659611 https://reactome.org/PathwayBrowser/#/R-CFA-9659611 ANO1 inhibitors bind ANO1 IEA Canis familiaris 34507 R-DDI-9659611 https://reactome.org/PathwayBrowser/#/R-DDI-9659611 ANO1 inhibitors bind ANO1 IEA Dictyostelium discoideum 34507 R-GGA-9659611 https://reactome.org/PathwayBrowser/#/R-GGA-9659611 ANO1 inhibitors bind ANO1 IEA Gallus gallus 34507 R-HSA-9659611 https://reactome.org/PathwayBrowser/#/R-HSA-9659611 ANO1 inhibitors bind ANO1 TAS Homo sapiens 34507 R-MMU-9659611 https://reactome.org/PathwayBrowser/#/R-MMU-9659611 ANO1 inhibitors bind ANO1 IEA Mus musculus 34507 R-RNO-9659611 https://reactome.org/PathwayBrowser/#/R-RNO-9659611 ANO1 inhibitors bind ANO1 IEA Rattus norvegicus 34507 R-SCE-9659611 https://reactome.org/PathwayBrowser/#/R-SCE-9659611 ANO1 inhibitors bind ANO1 IEA Saccharomyces cerevisiae 34507 R-SPO-9659611 https://reactome.org/PathwayBrowser/#/R-SPO-9659611 ANO1 inhibitors bind ANO1 IEA Schizosaccharomyces pombe 34507 R-SSC-9659611 https://reactome.org/PathwayBrowser/#/R-SSC-9659611 ANO1 inhibitors bind ANO1 IEA Sus scrofa 34507 R-XTR-9659611 https://reactome.org/PathwayBrowser/#/R-XTR-9659611 ANO1 inhibitors bind ANO1 IEA Xenopus tropicalis 34522 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 34522 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 34522 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 34522 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 34522 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 34522 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 34522 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 34522 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 34522 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 34536 R-BTA-9629679 https://reactome.org/PathwayBrowser/#/R-BTA-9629679 PDE3A inhibitors bind PDE3A IEA Bos taurus 34536 R-CEL-9629679 https://reactome.org/PathwayBrowser/#/R-CEL-9629679 PDE3A inhibitors bind PDE3A IEA Caenorhabditis elegans 34536 R-CFA-9629679 https://reactome.org/PathwayBrowser/#/R-CFA-9629679 PDE3A inhibitors bind PDE3A IEA Canis familiaris 34536 R-DDI-9629679 https://reactome.org/PathwayBrowser/#/R-DDI-9629679 PDE3A inhibitors bind PDE3A IEA Dictyostelium discoideum 34536 R-GGA-9629679 https://reactome.org/PathwayBrowser/#/R-GGA-9629679 PDE3A inhibitors bind PDE3A IEA Gallus gallus 34536 R-HSA-9629679 https://reactome.org/PathwayBrowser/#/R-HSA-9629679 PDE3A inhibitors bind PDE3A TAS Homo sapiens 34536 R-MMU-9629679 https://reactome.org/PathwayBrowser/#/R-MMU-9629679 PDE3A inhibitors bind PDE3A IEA Mus musculus 34536 R-PFA-9629679 https://reactome.org/PathwayBrowser/#/R-PFA-9629679 PDE3A inhibitors bind PDE3A IEA Plasmodium falciparum 34536 R-RNO-9629679 https://reactome.org/PathwayBrowser/#/R-RNO-9629679 PDE3A inhibitors bind PDE3A IEA Rattus norvegicus 34536 R-SSC-9629679 https://reactome.org/PathwayBrowser/#/R-SSC-9629679 PDE3A inhibitors bind PDE3A IEA Sus scrofa 34560 R-BTA-5694077 https://reactome.org/PathwayBrowser/#/R-BTA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Bos taurus 34560 R-CEL-5694077 https://reactome.org/PathwayBrowser/#/R-CEL-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Caenorhabditis elegans 34560 R-CFA-5694077 https://reactome.org/PathwayBrowser/#/R-CFA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Canis familiaris 34560 R-DME-5694077 https://reactome.org/PathwayBrowser/#/R-DME-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Drosophila melanogaster 34560 R-GGA-5694077 https://reactome.org/PathwayBrowser/#/R-GGA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Gallus gallus 34560 R-HSA-5694077 https://reactome.org/PathwayBrowser/#/R-HSA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD TAS Homo sapiens 34560 R-MMU-5694077 https://reactome.org/PathwayBrowser/#/R-MMU-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Mus musculus 34560 R-RNO-5694077 https://reactome.org/PathwayBrowser/#/R-RNO-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Rattus norvegicus 34560 R-SSC-5694077 https://reactome.org/PathwayBrowser/#/R-SSC-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Sus scrofa 34660 R-BTA-2161195 https://reactome.org/PathwayBrowser/#/R-BTA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Bos taurus 34660 R-CEL-2161195 https://reactome.org/PathwayBrowser/#/R-CEL-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Caenorhabditis elegans 34660 R-CFA-2161195 https://reactome.org/PathwayBrowser/#/R-CFA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Canis familiaris 34660 R-DME-2161195 https://reactome.org/PathwayBrowser/#/R-DME-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Drosophila melanogaster 34660 R-DRE-2161195 https://reactome.org/PathwayBrowser/#/R-DRE-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Danio rerio 34660 R-GGA-2161195 https://reactome.org/PathwayBrowser/#/R-GGA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Gallus gallus 34660 R-HSA-2161195 https://reactome.org/PathwayBrowser/#/R-HSA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine TAS Homo sapiens 34660 R-MMU-2161195 https://reactome.org/PathwayBrowser/#/R-MMU-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Mus musculus 34660 R-SSC-2161195 https://reactome.org/PathwayBrowser/#/R-SSC-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Sus scrofa 34660 R-XTR-2161195 https://reactome.org/PathwayBrowser/#/R-XTR-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Xenopus tropicalis 34665 R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 34665 R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 34665 R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 34665 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 34665 R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 34665 R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 34665 R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 34665 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 34665 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 34665 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 34665 R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 34665 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 34665 R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 34665 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 34665 R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 34665 R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa 34665 R-XTR-211966 https://reactome.org/PathwayBrowser/#/R-XTR-211966 CYP2D6 4-hydroxylates debrisoquine IEA Xenopus tropicalis 34674 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 34674 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 34674 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 34674 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 34674 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 34674 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 34674 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 34718 R-BTA-176054 https://reactome.org/PathwayBrowser/#/R-BTA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Bos taurus 34718 R-BTA-3301943 https://reactome.org/PathwayBrowser/#/R-BTA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Bos taurus 34718 R-CEL-176054 https://reactome.org/PathwayBrowser/#/R-CEL-176054 GST dimers conjugate GSH with cytosolic substrates IEA Caenorhabditis elegans 34718 R-CEL-3301943 https://reactome.org/PathwayBrowser/#/R-CEL-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Caenorhabditis elegans 34718 R-CFA-176054 https://reactome.org/PathwayBrowser/#/R-CFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Canis familiaris 34718 R-CFA-3301943 https://reactome.org/PathwayBrowser/#/R-CFA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Canis familiaris 34718 R-DDI-176054 https://reactome.org/PathwayBrowser/#/R-DDI-176054 GST dimers conjugate GSH with cytosolic substrates IEA Dictyostelium discoideum 34718 R-DME-176054 https://reactome.org/PathwayBrowser/#/R-DME-176054 GST dimers conjugate GSH with cytosolic substrates IEA Drosophila melanogaster 34718 R-DRE-176054 https://reactome.org/PathwayBrowser/#/R-DRE-176054 GST dimers conjugate GSH with cytosolic substrates IEA Danio rerio 34718 R-DRE-3301943 https://reactome.org/PathwayBrowser/#/R-DRE-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Danio rerio 34718 R-GGA-176054 https://reactome.org/PathwayBrowser/#/R-GGA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Gallus gallus 34718 R-GGA-3301943 https://reactome.org/PathwayBrowser/#/R-GGA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Gallus gallus 34718 R-HSA-176054 https://reactome.org/PathwayBrowser/#/R-HSA-176054 GST dimers conjugate GSH with cytosolic substrates TAS Homo sapiens 34718 R-HSA-3301943 https://reactome.org/PathwayBrowser/#/R-HSA-3301943 GSTK1 dimer transfers GS from GSH to CDNB TAS Homo sapiens 34718 R-MMU-176054 https://reactome.org/PathwayBrowser/#/R-MMU-176054 GST dimers conjugate GSH with cytosolic substrates IEA Mus musculus 34718 R-MMU-3301943 https://reactome.org/PathwayBrowser/#/R-MMU-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Mus musculus 34718 R-PFA-176054 https://reactome.org/PathwayBrowser/#/R-PFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Plasmodium falciparum 34718 R-RNO-176054 https://reactome.org/PathwayBrowser/#/R-RNO-176054 GST dimers conjugate GSH with cytosolic substrates IEA Rattus norvegicus 34718 R-RNO-3301943 https://reactome.org/PathwayBrowser/#/R-RNO-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Rattus norvegicus 34718 R-SSC-176054 https://reactome.org/PathwayBrowser/#/R-SSC-176054 GST dimers conjugate GSH with cytosolic substrates IEA Sus scrofa 34718 R-SSC-3301943 https://reactome.org/PathwayBrowser/#/R-SSC-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Sus scrofa 34718 R-XTR-176054 https://reactome.org/PathwayBrowser/#/R-XTR-176054 GST dimers conjugate GSH with cytosolic substrates IEA Xenopus tropicalis 34732 R-BTA-9613264 https://reactome.org/PathwayBrowser/#/R-BTA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Bos taurus 34732 R-CFA-9613264 https://reactome.org/PathwayBrowser/#/R-CFA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Canis familiaris 34732 R-GGA-9613264 https://reactome.org/PathwayBrowser/#/R-GGA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Gallus gallus 34732 R-HSA-9613264 https://reactome.org/PathwayBrowser/#/R-HSA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE TAS Homo sapiens 34732 R-MMU-9613264 https://reactome.org/PathwayBrowser/#/R-MMU-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Mus musculus 34732 R-RNO-9613264 https://reactome.org/PathwayBrowser/#/R-RNO-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Rattus norvegicus 34732 R-SSC-9613264 https://reactome.org/PathwayBrowser/#/R-SSC-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Sus scrofa 34750 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 34750 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 34750 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 34750 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 34750 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 34750 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 34750 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 34750 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 34750 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 34750 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 34778 R-CFA-8941701 https://reactome.org/PathwayBrowser/#/R-CFA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Canis familiaris 34778 R-DDI-8941701 https://reactome.org/PathwayBrowser/#/R-DDI-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Dictyostelium discoideum 34778 R-GGA-8941701 https://reactome.org/PathwayBrowser/#/R-GGA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Gallus gallus 34778 R-HSA-8941701 https://reactome.org/PathwayBrowser/#/R-HSA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN TAS Homo sapiens 34778 R-MMU-8941701 https://reactome.org/PathwayBrowser/#/R-MMU-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Mus musculus 34778 R-RNO-8941701 https://reactome.org/PathwayBrowser/#/R-RNO-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Rattus norvegicus 34784 R-BTA-2161794 https://reactome.org/PathwayBrowser/#/R-BTA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Bos taurus 34784 R-CFA-2161794 https://reactome.org/PathwayBrowser/#/R-CFA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Canis familiaris 34784 R-DDI-2161794 https://reactome.org/PathwayBrowser/#/R-DDI-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Dictyostelium discoideum 34784 R-DRE-2161794 https://reactome.org/PathwayBrowser/#/R-DRE-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Danio rerio 34784 R-HSA-2161794 https://reactome.org/PathwayBrowser/#/R-HSA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 TAS Homo sapiens 34784 R-HSA-2161949 https://reactome.org/PathwayBrowser/#/R-HSA-2161949 HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH TAS Homo sapiens 34784 R-MMU-2161794 https://reactome.org/PathwayBrowser/#/R-MMU-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Mus musculus 34784 R-RNO-2161794 https://reactome.org/PathwayBrowser/#/R-RNO-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Rattus norvegicus 34784 R-SSC-2161794 https://reactome.org/PathwayBrowser/#/R-SSC-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Sus scrofa 34888 R-BTA-9659611 https://reactome.org/PathwayBrowser/#/R-BTA-9659611 ANO1 inhibitors bind ANO1 IEA Bos taurus 34888 R-CFA-9659611 https://reactome.org/PathwayBrowser/#/R-CFA-9659611 ANO1 inhibitors bind ANO1 IEA Canis familiaris 34888 R-DDI-9659611 https://reactome.org/PathwayBrowser/#/R-DDI-9659611 ANO1 inhibitors bind ANO1 IEA Dictyostelium discoideum 34888 R-GGA-9659611 https://reactome.org/PathwayBrowser/#/R-GGA-9659611 ANO1 inhibitors bind ANO1 IEA Gallus gallus 34888 R-HSA-9659611 https://reactome.org/PathwayBrowser/#/R-HSA-9659611 ANO1 inhibitors bind ANO1 TAS Homo sapiens 34888 R-MMU-9659611 https://reactome.org/PathwayBrowser/#/R-MMU-9659611 ANO1 inhibitors bind ANO1 IEA Mus musculus 34888 R-RNO-9659611 https://reactome.org/PathwayBrowser/#/R-RNO-9659611 ANO1 inhibitors bind ANO1 IEA Rattus norvegicus 34888 R-SCE-9659611 https://reactome.org/PathwayBrowser/#/R-SCE-9659611 ANO1 inhibitors bind ANO1 IEA Saccharomyces cerevisiae 34888 R-SPO-9659611 https://reactome.org/PathwayBrowser/#/R-SPO-9659611 ANO1 inhibitors bind ANO1 IEA Schizosaccharomyces pombe 34888 R-SSC-9659611 https://reactome.org/PathwayBrowser/#/R-SSC-9659611 ANO1 inhibitors bind ANO1 IEA Sus scrofa 34888 R-XTR-9659611 https://reactome.org/PathwayBrowser/#/R-XTR-9659611 ANO1 inhibitors bind ANO1 IEA Xenopus tropicalis 35032 R-HSA-2161949 https://reactome.org/PathwayBrowser/#/R-HSA-2161949 HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH TAS Homo sapiens 350546 R-BTA-141186 https://reactome.org/PathwayBrowser/#/R-BTA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Bos taurus 350546 R-BTA-209792 https://reactome.org/PathwayBrowser/#/R-BTA-209792 N-acetylation of serotonin IEA Bos taurus 350546 R-BTA-209859 https://reactome.org/PathwayBrowser/#/R-BTA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Bos taurus 350546 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 350546 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 350546 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 350546 R-BTA-380586 https://reactome.org/PathwayBrowser/#/R-BTA-380586 loading of Serotonin in synaptic vesicles IEA Bos taurus 350546 R-BTA-380901 https://reactome.org/PathwayBrowser/#/R-BTA-380901 Release of docked serotonin loaded synaptic vesicle IEA Bos taurus 350546 R-BTA-380905 https://reactome.org/PathwayBrowser/#/R-BTA-380905 Serotonin loaded synaptic vesicle docking and priming IEA Bos taurus 350546 R-BTA-390929 https://reactome.org/PathwayBrowser/#/R-BTA-390929 HTR1 and 5A receptors can bind serotonin IEA Bos taurus 350546 R-BTA-390930 https://reactome.org/PathwayBrowser/#/R-BTA-390930 5-HT2 receptor can bind serotonin IEA Bos taurus 350546 R-BTA-390931 https://reactome.org/PathwayBrowser/#/R-BTA-390931 5-HT4, 6 and 7 receptors can bind serotonin IEA Bos taurus 350546 R-BTA-444008 https://reactome.org/PathwayBrowser/#/R-BTA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 350546 R-BTA-444160 https://reactome.org/PathwayBrowser/#/R-BTA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Bos taurus 350546 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 350546 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 350546 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 350546 R-BTA-727740 https://reactome.org/PathwayBrowser/#/R-BTA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 350546 R-BTA-727768 https://reactome.org/PathwayBrowser/#/R-BTA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 350546 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 350546 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 350546 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 350546 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 350546 R-BTA-9648949 https://reactome.org/PathwayBrowser/#/R-BTA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Bos taurus 350546 R-BTA-9648983 https://reactome.org/PathwayBrowser/#/R-BTA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Bos taurus 350546 R-BTA-9649108 https://reactome.org/PathwayBrowser/#/R-BTA-9649108 HTR3A pentamer binds 5HT IEA Bos taurus 350546 R-BTA-9693347 https://reactome.org/PathwayBrowser/#/R-BTA-9693347 HTR1A binds 5HT IEA Bos taurus 350546 R-BTA-975311 https://reactome.org/PathwayBrowser/#/R-BTA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Bos taurus 350546 R-CEL-209859 https://reactome.org/PathwayBrowser/#/R-CEL-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Caenorhabditis elegans 350546 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 350546 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 350546 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 350546 R-CEL-380586 https://reactome.org/PathwayBrowser/#/R-CEL-380586 loading of Serotonin in synaptic vesicles IEA Caenorhabditis elegans 350546 R-CEL-380901 https://reactome.org/PathwayBrowser/#/R-CEL-380901 Release of docked serotonin loaded synaptic vesicle IEA Caenorhabditis elegans 350546 R-CEL-380905 https://reactome.org/PathwayBrowser/#/R-CEL-380905 Serotonin loaded synaptic vesicle docking and priming IEA Caenorhabditis elegans 350546 R-CEL-390929 https://reactome.org/PathwayBrowser/#/R-CEL-390929 HTR1 and 5A receptors can bind serotonin IEA Caenorhabditis elegans 350546 R-CEL-390930 https://reactome.org/PathwayBrowser/#/R-CEL-390930 5-HT2 receptor can bind serotonin IEA Caenorhabditis elegans 350546 R-CEL-390931 https://reactome.org/PathwayBrowser/#/R-CEL-390931 5-HT4, 6 and 7 receptors can bind serotonin IEA Caenorhabditis elegans 350546 R-CEL-444008 https://reactome.org/PathwayBrowser/#/R-CEL-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 350546 R-CEL-444160 https://reactome.org/PathwayBrowser/#/R-CEL-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Caenorhabditis elegans 350546 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 350546 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 350546 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 350546 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 350546 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 350546 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 350546 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 350546 R-CEL-9648949 https://reactome.org/PathwayBrowser/#/R-CEL-9648949 HTR3A antagonists bind HTR3A pentamer IEA Caenorhabditis elegans 350546 R-CEL-9648983 https://reactome.org/PathwayBrowser/#/R-CEL-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Caenorhabditis elegans 350546 R-CEL-9649108 https://reactome.org/PathwayBrowser/#/R-CEL-9649108 HTR3A pentamer binds 5HT IEA Caenorhabditis elegans 350546 R-CEL-9693347 https://reactome.org/PathwayBrowser/#/R-CEL-9693347 HTR1A binds 5HT IEA Caenorhabditis elegans 350546 R-CEL-975311 https://reactome.org/PathwayBrowser/#/R-CEL-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Caenorhabditis elegans 350546 R-CFA-141186 https://reactome.org/PathwayBrowser/#/R-CFA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Canis familiaris 350546 R-CFA-209792 https://reactome.org/PathwayBrowser/#/R-CFA-209792 N-acetylation of serotonin IEA Canis familiaris 350546 R-CFA-209859 https://reactome.org/PathwayBrowser/#/R-CFA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Canis familiaris 350546 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 350546 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 350546 R-CFA-380586 https://reactome.org/PathwayBrowser/#/R-CFA-380586 loading of Serotonin in synaptic vesicles IEA Canis familiaris 350546 R-CFA-380901 https://reactome.org/PathwayBrowser/#/R-CFA-380901 Release of docked serotonin loaded synaptic vesicle IEA Canis familiaris 350546 R-CFA-380905 https://reactome.org/PathwayBrowser/#/R-CFA-380905 Serotonin loaded synaptic vesicle docking and priming IEA Canis familiaris 350546 R-CFA-390929 https://reactome.org/PathwayBrowser/#/R-CFA-390929 HTR1 and 5A receptors can bind serotonin IEA Canis familiaris 350546 R-CFA-390930 https://reactome.org/PathwayBrowser/#/R-CFA-390930 5-HT2 receptor can bind serotonin IEA Canis familiaris 350546 R-CFA-390931 https://reactome.org/PathwayBrowser/#/R-CFA-390931 5-HT4, 6 and 7 receptors can bind serotonin IEA Canis familiaris 350546 R-CFA-444008 https://reactome.org/PathwayBrowser/#/R-CFA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 350546 R-CFA-444160 https://reactome.org/PathwayBrowser/#/R-CFA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Canis familiaris 350546 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 350546 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 350546 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 350546 R-CFA-727740 https://reactome.org/PathwayBrowser/#/R-CFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 350546 R-CFA-727768 https://reactome.org/PathwayBrowser/#/R-CFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 350546 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 350546 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 350546 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 350546 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 350546 R-CFA-9648949 https://reactome.org/PathwayBrowser/#/R-CFA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Canis familiaris 350546 R-CFA-9648983 https://reactome.org/PathwayBrowser/#/R-CFA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Canis familiaris 350546 R-CFA-9649108 https://reactome.org/PathwayBrowser/#/R-CFA-9649108 HTR3A pentamer binds 5HT IEA Canis familiaris 350546 R-CFA-9693347 https://reactome.org/PathwayBrowser/#/R-CFA-9693347 HTR1A binds 5HT IEA Canis familiaris 350546 R-CFA-975311 https://reactome.org/PathwayBrowser/#/R-CFA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Canis familiaris 350546 R-DDI-141186 https://reactome.org/PathwayBrowser/#/R-DDI-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Dictyostelium discoideum 350546 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 350546 R-DDI-727740 https://reactome.org/PathwayBrowser/#/R-DDI-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 350546 R-DDI-727768 https://reactome.org/PathwayBrowser/#/R-DDI-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 350546 R-DME-209859 https://reactome.org/PathwayBrowser/#/R-DME-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Drosophila melanogaster 350546 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 350546 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 350546 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 350546 R-DME-380586 https://reactome.org/PathwayBrowser/#/R-DME-380586 loading of Serotonin in synaptic vesicles IEA Drosophila melanogaster 350546 R-DME-380901 https://reactome.org/PathwayBrowser/#/R-DME-380901 Release of docked serotonin loaded synaptic vesicle IEA Drosophila melanogaster 350546 R-DME-380905 https://reactome.org/PathwayBrowser/#/R-DME-380905 Serotonin loaded synaptic vesicle docking and priming IEA Drosophila melanogaster 350546 R-DME-390929 https://reactome.org/PathwayBrowser/#/R-DME-390929 HTR1 and 5A receptors can bind serotonin IEA Drosophila melanogaster 350546 R-DME-390930 https://reactome.org/PathwayBrowser/#/R-DME-390930 5-HT2 receptor can bind serotonin IEA Drosophila melanogaster 350546 R-DME-390931 https://reactome.org/PathwayBrowser/#/R-DME-390931 5-HT4, 6 and 7 receptors can bind serotonin IEA Drosophila melanogaster 350546 R-DME-444008 https://reactome.org/PathwayBrowser/#/R-DME-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 350546 R-DME-444160 https://reactome.org/PathwayBrowser/#/R-DME-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Drosophila melanogaster 350546 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 350546 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 350546 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 350546 R-DME-727740 https://reactome.org/PathwayBrowser/#/R-DME-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 350546 R-DME-727768 https://reactome.org/PathwayBrowser/#/R-DME-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 350546 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 350546 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 350546 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 350546 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 350546 R-DME-9693347 https://reactome.org/PathwayBrowser/#/R-DME-9693347 HTR1A binds 5HT IEA Drosophila melanogaster 350546 R-DRE-209792 https://reactome.org/PathwayBrowser/#/R-DRE-209792 N-acetylation of serotonin IEA Danio rerio 350546 R-DRE-209859 https://reactome.org/PathwayBrowser/#/R-DRE-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Danio rerio 350546 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 350546 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 350546 R-DRE-390929 https://reactome.org/PathwayBrowser/#/R-DRE-390929 HTR1 and 5A receptors can bind serotonin IEA Danio rerio 350546 R-DRE-390930 https://reactome.org/PathwayBrowser/#/R-DRE-390930 5-HT2 receptor can bind serotonin IEA Danio rerio 350546 R-DRE-390931 https://reactome.org/PathwayBrowser/#/R-DRE-390931 5-HT4, 6 and 7 receptors can bind serotonin IEA Danio rerio 350546 R-DRE-444008 https://reactome.org/PathwayBrowser/#/R-DRE-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Danio rerio 350546 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 350546 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 350546 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 350546 R-DRE-727740 https://reactome.org/PathwayBrowser/#/R-DRE-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 350546 R-DRE-727768 https://reactome.org/PathwayBrowser/#/R-DRE-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 350546 R-DRE-9693347 https://reactome.org/PathwayBrowser/#/R-DRE-9693347 HTR1A binds 5HT IEA Danio rerio 350546 R-GGA-141186 https://reactome.org/PathwayBrowser/#/R-GGA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Gallus gallus 350546 R-GGA-209792 https://reactome.org/PathwayBrowser/#/R-GGA-209792 N-acetylation of serotonin IEA Gallus gallus 350546 R-GGA-209859 https://reactome.org/PathwayBrowser/#/R-GGA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Gallus gallus 350546 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 350546 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 350546 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 350546 R-GGA-380586 https://reactome.org/PathwayBrowser/#/R-GGA-380586 loading of Serotonin in synaptic vesicles IEA Gallus gallus 350546 R-GGA-390929 https://reactome.org/PathwayBrowser/#/R-GGA-390929 HTR1 and 5A receptors can bind serotonin IEA Gallus gallus 350546 R-GGA-390930 https://reactome.org/PathwayBrowser/#/R-GGA-390930 5-HT2 receptor can bind serotonin IEA Gallus gallus 350546 R-GGA-390931 https://reactome.org/PathwayBrowser/#/R-GGA-390931 5-HT4, 6 and 7 receptors can bind serotonin IEA Gallus gallus 350546 R-GGA-444008 https://reactome.org/PathwayBrowser/#/R-GGA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 350546 R-GGA-444160 https://reactome.org/PathwayBrowser/#/R-GGA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Gallus gallus 350546 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 350546 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 350546 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 350546 R-GGA-727740 https://reactome.org/PathwayBrowser/#/R-GGA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 350546 R-GGA-727768 https://reactome.org/PathwayBrowser/#/R-GGA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 350546 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 350546 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 350546 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 350546 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 350546 R-GGA-9693347 https://reactome.org/PathwayBrowser/#/R-GGA-9693347 HTR1A binds 5HT IEA Gallus gallus 350546 R-HSA-141186 https://reactome.org/PathwayBrowser/#/R-HSA-141186 MAOA:FAD oxidatively deaminates of 5HT TAS Homo sapiens 350546 R-HSA-209792 https://reactome.org/PathwayBrowser/#/R-HSA-209792 N-acetylation of serotonin TAS Homo sapiens 350546 R-HSA-209859 https://reactome.org/PathwayBrowser/#/R-HSA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin TAS Homo sapiens 350546 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 350546 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 350546 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 350546 R-HSA-380586 https://reactome.org/PathwayBrowser/#/R-HSA-380586 loading of Serotonin in synaptic vesicles TAS Homo sapiens 350546 R-HSA-380620 https://reactome.org/PathwayBrowser/#/R-HSA-380620 Reuptake of serotonin from the synapse TAS Homo sapiens 350546 R-HSA-380901 https://reactome.org/PathwayBrowser/#/R-HSA-380901 Release of docked serotonin loaded synaptic vesicle TAS Homo sapiens 350546 R-HSA-380905 https://reactome.org/PathwayBrowser/#/R-HSA-380905 Serotonin loaded synaptic vesicle docking and priming TAS Homo sapiens 350546 R-HSA-390929 https://reactome.org/PathwayBrowser/#/R-HSA-390929 HTR1 and 5A receptors can bind serotonin TAS Homo sapiens 350546 R-HSA-390930 https://reactome.org/PathwayBrowser/#/R-HSA-390930 5-HT2 receptor can bind serotonin TAS Homo sapiens 350546 R-HSA-390931 https://reactome.org/PathwayBrowser/#/R-HSA-390931 5-HT4, 6 and 7 receptors can bind serotonin TAS Homo sapiens 350546 R-HSA-444008 https://reactome.org/PathwayBrowser/#/R-HSA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 350546 R-HSA-444160 https://reactome.org/PathwayBrowser/#/R-HSA-444160 VMAT1/2 can mediate the transport of biogenic amines TAS Homo sapiens 350546 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 350546 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 350546 R-HSA-5603108 https://reactome.org/PathwayBrowser/#/R-HSA-5603108 Defective MAOA does not oxidatively deaminate 5HT TAS Homo sapiens 350546 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 350546 R-HSA-727740 https://reactome.org/PathwayBrowser/#/R-HSA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 350546 R-HSA-727768 https://reactome.org/PathwayBrowser/#/R-HSA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 350546 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 350546 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 350546 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 350546 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 350546 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 350546 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 350546 R-HSA-9648949 https://reactome.org/PathwayBrowser/#/R-HSA-9648949 HTR3A antagonists bind HTR3A pentamer TAS Homo sapiens 350546 R-HSA-9648983 https://reactome.org/PathwayBrowser/#/R-HSA-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ TAS Homo sapiens 350546 R-HSA-9649108 https://reactome.org/PathwayBrowser/#/R-HSA-9649108 HTR3A pentamer binds 5HT TAS Homo sapiens 350546 R-HSA-9693347 https://reactome.org/PathwayBrowser/#/R-HSA-9693347 HTR1A binds 5HT TAS Homo sapiens 350546 R-HSA-975311 https://reactome.org/PathwayBrowser/#/R-HSA-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ TAS Homo sapiens 350546 R-MMU-141186 https://reactome.org/PathwayBrowser/#/R-MMU-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Mus musculus 350546 R-MMU-209792 https://reactome.org/PathwayBrowser/#/R-MMU-209792 N-acetylation of serotonin IEA Mus musculus 350546 R-MMU-209859 https://reactome.org/PathwayBrowser/#/R-MMU-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Mus musculus 350546 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 350546 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 350546 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 350546 R-MMU-380586 https://reactome.org/PathwayBrowser/#/R-MMU-380586 loading of Serotonin in synaptic vesicles IEA Mus musculus 350546 R-MMU-380901 https://reactome.org/PathwayBrowser/#/R-MMU-380901 Release of docked serotonin loaded synaptic vesicle IEA Mus musculus 350546 R-MMU-380905 https://reactome.org/PathwayBrowser/#/R-MMU-380905 Serotonin loaded synaptic vesicle docking and priming IEA Mus musculus 350546 R-MMU-390929 https://reactome.org/PathwayBrowser/#/R-MMU-390929 HTR1 and 5A receptors can bind serotonin IEA Mus musculus 350546 R-MMU-390930 https://reactome.org/PathwayBrowser/#/R-MMU-390930 5-HT2 receptor can bind serotonin IEA Mus musculus 350546 R-MMU-390931 https://reactome.org/PathwayBrowser/#/R-MMU-390931 5-HT4, 6 and 7 receptors can bind serotonin IEA Mus musculus 350546 R-MMU-444008 https://reactome.org/PathwayBrowser/#/R-MMU-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 350546 R-MMU-444160 https://reactome.org/PathwayBrowser/#/R-MMU-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Mus musculus 350546 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 350546 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 350546 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 350546 R-MMU-727740 https://reactome.org/PathwayBrowser/#/R-MMU-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 350546 R-MMU-727768 https://reactome.org/PathwayBrowser/#/R-MMU-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 350546 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 350546 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 350546 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 350546 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 350546 R-MMU-9648949 https://reactome.org/PathwayBrowser/#/R-MMU-9648949 HTR3A antagonists bind HTR3A pentamer IEA Mus musculus 350546 R-MMU-9648983 https://reactome.org/PathwayBrowser/#/R-MMU-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Mus musculus 350546 R-MMU-9649108 https://reactome.org/PathwayBrowser/#/R-MMU-9649108 HTR3A pentamer binds 5HT IEA Mus musculus 350546 R-MMU-9693347 https://reactome.org/PathwayBrowser/#/R-MMU-9693347 HTR1A binds 5HT IEA Mus musculus 350546 R-MMU-975311 https://reactome.org/PathwayBrowser/#/R-MMU-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Mus musculus 350546 R-PFA-444008 https://reactome.org/PathwayBrowser/#/R-PFA-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 350546 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 350546 R-PFA-727740 https://reactome.org/PathwayBrowser/#/R-PFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 350546 R-PFA-727768 https://reactome.org/PathwayBrowser/#/R-PFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 350546 R-RNO-141186 https://reactome.org/PathwayBrowser/#/R-RNO-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Rattus norvegicus 350546 R-RNO-209792 https://reactome.org/PathwayBrowser/#/R-RNO-209792 N-acetylation of serotonin IEA Rattus norvegicus 350546 R-RNO-209859 https://reactome.org/PathwayBrowser/#/R-RNO-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Rattus norvegicus 350546 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 350546 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 350546 R-RNO-380586 https://reactome.org/PathwayBrowser/#/R-RNO-380586 loading of Serotonin in synaptic vesicles IEA Rattus norvegicus 350546 R-RNO-380901 https://reactome.org/PathwayBrowser/#/R-RNO-380901 Release of docked serotonin loaded synaptic vesicle IEA Rattus norvegicus 350546 R-RNO-380905 https://reactome.org/PathwayBrowser/#/R-RNO-380905 Serotonin loaded synaptic vesicle docking and priming IEA Rattus norvegicus 350546 R-RNO-390929 https://reactome.org/PathwayBrowser/#/R-RNO-390929 HTR1 and 5A receptors can bind serotonin IEA Rattus norvegicus 350546 R-RNO-390930 https://reactome.org/PathwayBrowser/#/R-RNO-390930 5-HT2 receptor can bind serotonin IEA Rattus norvegicus 350546 R-RNO-390931 https://reactome.org/PathwayBrowser/#/R-RNO-390931 5-HT4, 6 and 7 receptors can bind serotonin IEA Rattus norvegicus 350546 R-RNO-444008 https://reactome.org/PathwayBrowser/#/R-RNO-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 350546 R-RNO-444160 https://reactome.org/PathwayBrowser/#/R-RNO-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Rattus norvegicus 350546 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 350546 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 350546 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 350546 R-RNO-727740 https://reactome.org/PathwayBrowser/#/R-RNO-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 350546 R-RNO-727768 https://reactome.org/PathwayBrowser/#/R-RNO-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 350546 R-RNO-9648949 https://reactome.org/PathwayBrowser/#/R-RNO-9648949 HTR3A antagonists bind HTR3A pentamer IEA Rattus norvegicus 350546 R-RNO-9648983 https://reactome.org/PathwayBrowser/#/R-RNO-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Rattus norvegicus 350546 R-RNO-9649108 https://reactome.org/PathwayBrowser/#/R-RNO-9649108 HTR3A pentamer binds 5HT IEA Rattus norvegicus 350546 R-RNO-9693347 https://reactome.org/PathwayBrowser/#/R-RNO-9693347 HTR1A binds 5HT IEA Rattus norvegicus 350546 R-RNO-975311 https://reactome.org/PathwayBrowser/#/R-RNO-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Rattus norvegicus 350546 R-SCE-209792 https://reactome.org/PathwayBrowser/#/R-SCE-209792 N-acetylation of serotonin IEA Saccharomyces cerevisiae 350546 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 350546 R-SPO-209792 https://reactome.org/PathwayBrowser/#/R-SPO-209792 N-acetylation of serotonin IEA Schizosaccharomyces pombe 350546 R-SPO-380586 https://reactome.org/PathwayBrowser/#/R-SPO-380586 loading of Serotonin in synaptic vesicles IEA Schizosaccharomyces pombe 350546 R-SPO-444160 https://reactome.org/PathwayBrowser/#/R-SPO-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Schizosaccharomyces pombe 350546 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 350546 R-SSC-141186 https://reactome.org/PathwayBrowser/#/R-SSC-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Sus scrofa 350546 R-SSC-209792 https://reactome.org/PathwayBrowser/#/R-SSC-209792 N-acetylation of serotonin IEA Sus scrofa 350546 R-SSC-209859 https://reactome.org/PathwayBrowser/#/R-SSC-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Sus scrofa 350546 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 350546 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 350546 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 350546 R-SSC-380586 https://reactome.org/PathwayBrowser/#/R-SSC-380586 loading of Serotonin in synaptic vesicles IEA Sus scrofa 350546 R-SSC-380901 https://reactome.org/PathwayBrowser/#/R-SSC-380901 Release of docked serotonin loaded synaptic vesicle IEA Sus scrofa 350546 R-SSC-380905 https://reactome.org/PathwayBrowser/#/R-SSC-380905 Serotonin loaded synaptic vesicle docking and priming IEA Sus scrofa 350546 R-SSC-390929 https://reactome.org/PathwayBrowser/#/R-SSC-390929 HTR1 and 5A receptors can bind serotonin IEA Sus scrofa 350546 R-SSC-390930 https://reactome.org/PathwayBrowser/#/R-SSC-390930 5-HT2 receptor can bind serotonin IEA Sus scrofa 350546 R-SSC-390931 https://reactome.org/PathwayBrowser/#/R-SSC-390931 5-HT4, 6 and 7 receptors can bind serotonin IEA Sus scrofa 350546 R-SSC-444008 https://reactome.org/PathwayBrowser/#/R-SSC-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 350546 R-SSC-444160 https://reactome.org/PathwayBrowser/#/R-SSC-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Sus scrofa 350546 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 350546 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 350546 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 350546 R-SSC-727740 https://reactome.org/PathwayBrowser/#/R-SSC-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 350546 R-SSC-727768 https://reactome.org/PathwayBrowser/#/R-SSC-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 350546 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 350546 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 350546 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 350546 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 350546 R-SSC-9648949 https://reactome.org/PathwayBrowser/#/R-SSC-9648949 HTR3A antagonists bind HTR3A pentamer IEA Sus scrofa 350546 R-SSC-9648983 https://reactome.org/PathwayBrowser/#/R-SSC-9648983 HTR3A pentamer:5HT transports Na+,K+,Ca2+ IEA Sus scrofa 350546 R-SSC-9649108 https://reactome.org/PathwayBrowser/#/R-SSC-9649108 HTR3A pentamer binds 5HT IEA Sus scrofa 350546 R-SSC-975311 https://reactome.org/PathwayBrowser/#/R-SSC-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Sus scrofa 350546 R-XTR-209859 https://reactome.org/PathwayBrowser/#/R-XTR-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Xenopus tropicalis 350546 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 350546 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 350546 R-XTR-380586 https://reactome.org/PathwayBrowser/#/R-XTR-380586 loading of Serotonin in synaptic vesicles IEA Xenopus tropicalis 350546 R-XTR-390929 https://reactome.org/PathwayBrowser/#/R-XTR-390929 HTR1 and 5A receptors can bind serotonin IEA Xenopus tropicalis 350546 R-XTR-390930 https://reactome.org/PathwayBrowser/#/R-XTR-390930 5-HT2 receptor can bind serotonin IEA Xenopus tropicalis 350546 R-XTR-390931 https://reactome.org/PathwayBrowser/#/R-XTR-390931 5-HT4, 6 and 7 receptors can bind serotonin IEA Xenopus tropicalis 350546 R-XTR-444008 https://reactome.org/PathwayBrowser/#/R-XTR-444008 SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 350546 R-XTR-444160 https://reactome.org/PathwayBrowser/#/R-XTR-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Xenopus tropicalis 350546 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 350546 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 350546 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 350546 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 350546 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 350546 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 350546 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 350546 R-XTR-9693347 https://reactome.org/PathwayBrowser/#/R-XTR-9693347 HTR1A binds 5HT IEA Xenopus tropicalis 351346 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 351346 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 351346 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 351346 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 351346 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 351346 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 351346 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 351346 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 351346 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 351346 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 351346 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 351346 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 351346 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 351346 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 351346 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 351346 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 351346 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 351346 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 351346 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 351346 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 351346 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 351346 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 351346 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 351346 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 351346 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 351346 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 351346 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 351346 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 351346 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 351346 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 351346 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 351346 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 351346 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 351346 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 351346 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 351346 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 351346 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 351346 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 351346 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 351346 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 351346 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 351346 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 35179 R-CFS-1237106 https://reactome.org/PathwayBrowser/#/R-CFS-1237106 Transamination of MOB to methionine TAS Crithidia fasciculata 35179 R-HSA-1237102 https://reactome.org/PathwayBrowser/#/R-HSA-1237102 Transamination of MOB to methionine IEA Homo sapiens 35235 R-BTA-1247910 https://reactome.org/PathwayBrowser/#/R-BTA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Bos taurus 35235 R-BTA-1247922 https://reactome.org/PathwayBrowser/#/R-BTA-1247922 GGCT transforms gGluCys to OPRO IEA Bos taurus 35235 R-BTA-1362408 https://reactome.org/PathwayBrowser/#/R-BTA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Bos taurus 35235 R-BTA-1614583 https://reactome.org/PathwayBrowser/#/R-BTA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Bos taurus 35235 R-BTA-1614591 https://reactome.org/PathwayBrowser/#/R-BTA-1614591 Excess cysteine yields lanthionine and H2S IEA Bos taurus 35235 R-BTA-1614614 https://reactome.org/PathwayBrowser/#/R-BTA-1614614 Cysteine is degraded to serine and H2S IEA Bos taurus 35235 R-BTA-1614645 https://reactome.org/PathwayBrowser/#/R-BTA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Bos taurus 35235 R-BTA-174367 https://reactome.org/PathwayBrowser/#/R-BTA-174367 GCL ligates L-Glu to L-Cys IEA Bos taurus 35235 R-BTA-196753 https://reactome.org/PathwayBrowser/#/R-BTA-196753 2xPPCS ligates PPanK with Cys IEA Bos taurus 35235 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 35235 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 35235 R-BTA-352347 https://reactome.org/PathwayBrowser/#/R-BTA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Bos taurus 35235 R-BTA-352354 https://reactome.org/PathwayBrowser/#/R-BTA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Bos taurus 35235 R-BTA-352364 https://reactome.org/PathwayBrowser/#/R-BTA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Bos taurus 35235 R-BTA-352371 https://reactome.org/PathwayBrowser/#/R-BTA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Bos taurus 35235 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 35235 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 35235 R-BTA-376200 https://reactome.org/PathwayBrowser/#/R-BTA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Bos taurus 35235 R-BTA-378513 https://reactome.org/PathwayBrowser/#/R-BTA-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Bos taurus 35235 R-BTA-947499 https://reactome.org/PathwayBrowser/#/R-BTA-947499 Exchange of oxygen with sulfur in MoCo IEA Bos taurus 35235 R-BTA-947514 https://reactome.org/PathwayBrowser/#/R-BTA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Bos taurus 35235 R-BTA-9753944 https://reactome.org/PathwayBrowser/#/R-BTA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Bos taurus 35235 R-CEL-1247910 https://reactome.org/PathwayBrowser/#/R-CEL-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Caenorhabditis elegans 35235 R-CEL-1247922 https://reactome.org/PathwayBrowser/#/R-CEL-1247922 GGCT transforms gGluCys to OPRO IEA Caenorhabditis elegans 35235 R-CEL-1362408 https://reactome.org/PathwayBrowser/#/R-CEL-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Caenorhabditis elegans 35235 R-CEL-1614583 https://reactome.org/PathwayBrowser/#/R-CEL-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Caenorhabditis elegans 35235 R-CEL-1614591 https://reactome.org/PathwayBrowser/#/R-CEL-1614591 Excess cysteine yields lanthionine and H2S IEA Caenorhabditis elegans 35235 R-CEL-1614614 https://reactome.org/PathwayBrowser/#/R-CEL-1614614 Cysteine is degraded to serine and H2S IEA Caenorhabditis elegans 35235 R-CEL-1614645 https://reactome.org/PathwayBrowser/#/R-CEL-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Caenorhabditis elegans 35235 R-CEL-174367 https://reactome.org/PathwayBrowser/#/R-CEL-174367 GCL ligates L-Glu to L-Cys IEA Caenorhabditis elegans 35235 R-CEL-196753 https://reactome.org/PathwayBrowser/#/R-CEL-196753 2xPPCS ligates PPanK with Cys IEA Caenorhabditis elegans 35235 R-CEL-352347 https://reactome.org/PathwayBrowser/#/R-CEL-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Caenorhabditis elegans 35235 R-CEL-352354 https://reactome.org/PathwayBrowser/#/R-CEL-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Caenorhabditis elegans 35235 R-CEL-352364 https://reactome.org/PathwayBrowser/#/R-CEL-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Caenorhabditis elegans 35235 R-CEL-352371 https://reactome.org/PathwayBrowser/#/R-CEL-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Caenorhabditis elegans 35235 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 35235 R-CEL-947499 https://reactome.org/PathwayBrowser/#/R-CEL-947499 Exchange of oxygen with sulfur in MoCo IEA Caenorhabditis elegans 35235 R-CEL-947514 https://reactome.org/PathwayBrowser/#/R-CEL-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Caenorhabditis elegans 35235 R-CEL-9753944 https://reactome.org/PathwayBrowser/#/R-CEL-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Caenorhabditis elegans 35235 R-CFA-1247910 https://reactome.org/PathwayBrowser/#/R-CFA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Canis familiaris 35235 R-CFA-1247922 https://reactome.org/PathwayBrowser/#/R-CFA-1247922 GGCT transforms gGluCys to OPRO IEA Canis familiaris 35235 R-CFA-1362408 https://reactome.org/PathwayBrowser/#/R-CFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Canis familiaris 35235 R-CFA-1614583 https://reactome.org/PathwayBrowser/#/R-CFA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Canis familiaris 35235 R-CFA-1614591 https://reactome.org/PathwayBrowser/#/R-CFA-1614591 Excess cysteine yields lanthionine and H2S IEA Canis familiaris 35235 R-CFA-1614614 https://reactome.org/PathwayBrowser/#/R-CFA-1614614 Cysteine is degraded to serine and H2S IEA Canis familiaris 35235 R-CFA-1614645 https://reactome.org/PathwayBrowser/#/R-CFA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Canis familiaris 35235 R-CFA-174367 https://reactome.org/PathwayBrowser/#/R-CFA-174367 GCL ligates L-Glu to L-Cys IEA Canis familiaris 35235 R-CFA-196753 https://reactome.org/PathwayBrowser/#/R-CFA-196753 2xPPCS ligates PPanK with Cys IEA Canis familiaris 35235 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 35235 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 35235 R-CFA-352347 https://reactome.org/PathwayBrowser/#/R-CFA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Canis familiaris 35235 R-CFA-352354 https://reactome.org/PathwayBrowser/#/R-CFA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Canis familiaris 35235 R-CFA-352364 https://reactome.org/PathwayBrowser/#/R-CFA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Canis familiaris 35235 R-CFA-352371 https://reactome.org/PathwayBrowser/#/R-CFA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Canis familiaris 35235 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 35235 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 35235 R-CFA-376200 https://reactome.org/PathwayBrowser/#/R-CFA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Canis familiaris 35235 R-CFA-378513 https://reactome.org/PathwayBrowser/#/R-CFA-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Canis familiaris 35235 R-CFA-947499 https://reactome.org/PathwayBrowser/#/R-CFA-947499 Exchange of oxygen with sulfur in MoCo IEA Canis familiaris 35235 R-CFA-947514 https://reactome.org/PathwayBrowser/#/R-CFA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Canis familiaris 35235 R-CFA-9753944 https://reactome.org/PathwayBrowser/#/R-CFA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Canis familiaris 35235 R-DDI-1247910 https://reactome.org/PathwayBrowser/#/R-DDI-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Dictyostelium discoideum 35235 R-DDI-1362408 https://reactome.org/PathwayBrowser/#/R-DDI-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Dictyostelium discoideum 35235 R-DDI-1614583 https://reactome.org/PathwayBrowser/#/R-DDI-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Dictyostelium discoideum 35235 R-DDI-1614591 https://reactome.org/PathwayBrowser/#/R-DDI-1614591 Excess cysteine yields lanthionine and H2S IEA Dictyostelium discoideum 35235 R-DDI-1614614 https://reactome.org/PathwayBrowser/#/R-DDI-1614614 Cysteine is degraded to serine and H2S IEA Dictyostelium discoideum 35235 R-DDI-1614645 https://reactome.org/PathwayBrowser/#/R-DDI-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Dictyostelium discoideum 35235 R-DDI-196753 https://reactome.org/PathwayBrowser/#/R-DDI-196753 2xPPCS ligates PPanK with Cys IEA Dictyostelium discoideum 35235 R-DDI-947499 https://reactome.org/PathwayBrowser/#/R-DDI-947499 Exchange of oxygen with sulfur in MoCo IEA Dictyostelium discoideum 35235 R-DDI-947514 https://reactome.org/PathwayBrowser/#/R-DDI-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Dictyostelium discoideum 35235 R-DDI-9753944 https://reactome.org/PathwayBrowser/#/R-DDI-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Dictyostelium discoideum 35235 R-DME-1247910 https://reactome.org/PathwayBrowser/#/R-DME-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Drosophila melanogaster 35235 R-DME-1247922 https://reactome.org/PathwayBrowser/#/R-DME-1247922 GGCT transforms gGluCys to OPRO IEA Drosophila melanogaster 35235 R-DME-1362408 https://reactome.org/PathwayBrowser/#/R-DME-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Drosophila melanogaster 35235 R-DME-1614583 https://reactome.org/PathwayBrowser/#/R-DME-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Drosophila melanogaster 35235 R-DME-1614591 https://reactome.org/PathwayBrowser/#/R-DME-1614591 Excess cysteine yields lanthionine and H2S IEA Drosophila melanogaster 35235 R-DME-1614614 https://reactome.org/PathwayBrowser/#/R-DME-1614614 Cysteine is degraded to serine and H2S IEA Drosophila melanogaster 35235 R-DME-1614645 https://reactome.org/PathwayBrowser/#/R-DME-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Drosophila melanogaster 35235 R-DME-174367 https://reactome.org/PathwayBrowser/#/R-DME-174367 GCL ligates L-Glu to L-Cys IEA Drosophila melanogaster 35235 R-DME-196753 https://reactome.org/PathwayBrowser/#/R-DME-196753 2xPPCS ligates PPanK with Cys IEA Drosophila melanogaster 35235 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 35235 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 35235 R-DME-352347 https://reactome.org/PathwayBrowser/#/R-DME-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Drosophila melanogaster 35235 R-DME-352354 https://reactome.org/PathwayBrowser/#/R-DME-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Drosophila melanogaster 35235 R-DME-352364 https://reactome.org/PathwayBrowser/#/R-DME-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Drosophila melanogaster 35235 R-DME-352371 https://reactome.org/PathwayBrowser/#/R-DME-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Drosophila melanogaster 35235 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 35235 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 35235 R-DME-376200 https://reactome.org/PathwayBrowser/#/R-DME-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Drosophila melanogaster 35235 R-DME-378513 https://reactome.org/PathwayBrowser/#/R-DME-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Drosophila melanogaster 35235 R-DME-947499 https://reactome.org/PathwayBrowser/#/R-DME-947499 Exchange of oxygen with sulfur in MoCo IEA Drosophila melanogaster 35235 R-DME-947514 https://reactome.org/PathwayBrowser/#/R-DME-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Drosophila melanogaster 35235 R-DME-9753944 https://reactome.org/PathwayBrowser/#/R-DME-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Drosophila melanogaster 35235 R-DRE-1247910 https://reactome.org/PathwayBrowser/#/R-DRE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Danio rerio 35235 R-DRE-1247922 https://reactome.org/PathwayBrowser/#/R-DRE-1247922 GGCT transforms gGluCys to OPRO IEA Danio rerio 35235 R-DRE-1362408 https://reactome.org/PathwayBrowser/#/R-DRE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Danio rerio 35235 R-DRE-1614583 https://reactome.org/PathwayBrowser/#/R-DRE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Danio rerio 35235 R-DRE-1614591 https://reactome.org/PathwayBrowser/#/R-DRE-1614591 Excess cysteine yields lanthionine and H2S IEA Danio rerio 35235 R-DRE-1614614 https://reactome.org/PathwayBrowser/#/R-DRE-1614614 Cysteine is degraded to serine and H2S IEA Danio rerio 35235 R-DRE-1614645 https://reactome.org/PathwayBrowser/#/R-DRE-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Danio rerio 35235 R-DRE-196753 https://reactome.org/PathwayBrowser/#/R-DRE-196753 2xPPCS ligates PPanK with Cys IEA Danio rerio 35235 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 35235 R-DRE-352347 https://reactome.org/PathwayBrowser/#/R-DRE-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Danio rerio 35235 R-DRE-352354 https://reactome.org/PathwayBrowser/#/R-DRE-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Danio rerio 35235 R-DRE-352364 https://reactome.org/PathwayBrowser/#/R-DRE-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Danio rerio 35235 R-DRE-352371 https://reactome.org/PathwayBrowser/#/R-DRE-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Danio rerio 35235 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 35235 R-DRE-947499 https://reactome.org/PathwayBrowser/#/R-DRE-947499 Exchange of oxygen with sulfur in MoCo IEA Danio rerio 35235 R-DRE-947514 https://reactome.org/PathwayBrowser/#/R-DRE-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Danio rerio 35235 R-GGA-1247910 https://reactome.org/PathwayBrowser/#/R-GGA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Gallus gallus 35235 R-GGA-1247922 https://reactome.org/PathwayBrowser/#/R-GGA-1247922 GGCT transforms gGluCys to OPRO IEA Gallus gallus 35235 R-GGA-1362408 https://reactome.org/PathwayBrowser/#/R-GGA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Gallus gallus 35235 R-GGA-1614583 https://reactome.org/PathwayBrowser/#/R-GGA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Gallus gallus 35235 R-GGA-1614591 https://reactome.org/PathwayBrowser/#/R-GGA-1614591 Excess cysteine yields lanthionine and H2S IEA Gallus gallus 35235 R-GGA-1614614 https://reactome.org/PathwayBrowser/#/R-GGA-1614614 Cysteine is degraded to serine and H2S IEA Gallus gallus 35235 R-GGA-1614645 https://reactome.org/PathwayBrowser/#/R-GGA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Gallus gallus 35235 R-GGA-196753 https://reactome.org/PathwayBrowser/#/R-GGA-196753 2xPPCS ligates PPanK with Cys IEA Gallus gallus 35235 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 35235 R-GGA-352347 https://reactome.org/PathwayBrowser/#/R-GGA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Gallus gallus 35235 R-GGA-352354 https://reactome.org/PathwayBrowser/#/R-GGA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Gallus gallus 35235 R-GGA-352364 https://reactome.org/PathwayBrowser/#/R-GGA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Gallus gallus 35235 R-GGA-352371 https://reactome.org/PathwayBrowser/#/R-GGA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Gallus gallus 35235 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 35235 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 35235 R-GGA-947499 https://reactome.org/PathwayBrowser/#/R-GGA-947499 Exchange of oxygen with sulfur in MoCo IEA Gallus gallus 35235 R-GGA-947514 https://reactome.org/PathwayBrowser/#/R-GGA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Gallus gallus 35235 R-GGA-9753944 https://reactome.org/PathwayBrowser/#/R-GGA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Gallus gallus 35235 R-HSA-1247910 https://reactome.org/PathwayBrowser/#/R-HSA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly TAS Homo sapiens 35235 R-HSA-1247922 https://reactome.org/PathwayBrowser/#/R-HSA-1247922 GGCT transforms gGluCys to OPRO TAS Homo sapiens 35235 R-HSA-1362408 https://reactome.org/PathwayBrowser/#/R-HSA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster TAS Homo sapiens 35235 R-HSA-1614583 https://reactome.org/PathwayBrowser/#/R-HSA-1614583 PXLP-K212-CTH cleaves L-Cystathionine TAS Homo sapiens 35235 R-HSA-1614591 https://reactome.org/PathwayBrowser/#/R-HSA-1614591 Excess cysteine yields lanthionine and H2S TAS Homo sapiens 35235 R-HSA-1614614 https://reactome.org/PathwayBrowser/#/R-HSA-1614614 Cysteine is degraded to serine and H2S TAS Homo sapiens 35235 R-HSA-1614645 https://reactome.org/PathwayBrowser/#/R-HSA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine TAS Homo sapiens 35235 R-HSA-174367 https://reactome.org/PathwayBrowser/#/R-HSA-174367 GCL ligates L-Glu to L-Cys TAS Homo sapiens 35235 R-HSA-196753 https://reactome.org/PathwayBrowser/#/R-HSA-196753 2xPPCS ligates PPanK with Cys TAS Homo sapiens 35235 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 35235 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 35235 R-HSA-352347 https://reactome.org/PathwayBrowser/#/R-HSA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine TAS Homo sapiens 35235 R-HSA-352354 https://reactome.org/PathwayBrowser/#/R-HSA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine TAS Homo sapiens 35235 R-HSA-352364 https://reactome.org/PathwayBrowser/#/R-HSA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine TAS Homo sapiens 35235 R-HSA-352371 https://reactome.org/PathwayBrowser/#/R-HSA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine TAS Homo sapiens 35235 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 35235 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 35235 R-HSA-376200 https://reactome.org/PathwayBrowser/#/R-HSA-376200 SLC7A10-mediated uptake of small neutral amino acids TAS Homo sapiens 35235 R-HSA-378513 https://reactome.org/PathwayBrowser/#/R-HSA-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate TAS Homo sapiens 35235 R-HSA-379887 https://reactome.org/PathwayBrowser/#/R-HSA-379887 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate TAS Homo sapiens 35235 R-HSA-380158 https://reactome.org/PathwayBrowser/#/R-HSA-380158 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate IEA Homo sapiens 35235 R-HSA-5602892 https://reactome.org/PathwayBrowser/#/R-HSA-5602892 Defective GCLC does not ligate L-Glu to L-Cys TAS Homo sapiens 35235 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 35235 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 35235 R-HSA-5662908 https://reactome.org/PathwayBrowser/#/R-HSA-5662908 Dopaquinone, cysteine form CD isomers TAS Homo sapiens 35235 R-HSA-6787447 https://reactome.org/PathwayBrowser/#/R-HSA-6787447 TRMU (MTO2, MTU1) transfers a sulfur atom to 5-taurinomethyluridine-34 in tRNA IEA Homo sapiens 35235 R-HSA-9012597 https://reactome.org/PathwayBrowser/#/R-HSA-9012597 GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu IEA Homo sapiens 35235 R-HSA-947499 https://reactome.org/PathwayBrowser/#/R-HSA-947499 Exchange of oxygen with sulfur in MoCo TAS Homo sapiens 35235 R-HSA-947514 https://reactome.org/PathwayBrowser/#/R-HSA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 TAS Homo sapiens 35235 R-HSA-9753944 https://reactome.org/PathwayBrowser/#/R-HSA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys TAS Homo sapiens 35235 R-MMU-1247910 https://reactome.org/PathwayBrowser/#/R-MMU-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Mus musculus 35235 R-MMU-1247922 https://reactome.org/PathwayBrowser/#/R-MMU-1247922 GGCT transforms gGluCys to OPRO IEA Mus musculus 35235 R-MMU-1362408 https://reactome.org/PathwayBrowser/#/R-MMU-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Mus musculus 35235 R-MMU-1614583 https://reactome.org/PathwayBrowser/#/R-MMU-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Mus musculus 35235 R-MMU-1614591 https://reactome.org/PathwayBrowser/#/R-MMU-1614591 Excess cysteine yields lanthionine and H2S IEA Mus musculus 35235 R-MMU-1614614 https://reactome.org/PathwayBrowser/#/R-MMU-1614614 Cysteine is degraded to serine and H2S IEA Mus musculus 35235 R-MMU-1614645 https://reactome.org/PathwayBrowser/#/R-MMU-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Mus musculus 35235 R-MMU-174367 https://reactome.org/PathwayBrowser/#/R-MMU-174367 GCL ligates L-Glu to L-Cys IEA Mus musculus 35235 R-MMU-196753 https://reactome.org/PathwayBrowser/#/R-MMU-196753 2xPPCS ligates PPanK with Cys IEA Mus musculus 35235 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 35235 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 35235 R-MMU-352347 https://reactome.org/PathwayBrowser/#/R-MMU-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Mus musculus 35235 R-MMU-352354 https://reactome.org/PathwayBrowser/#/R-MMU-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Mus musculus 35235 R-MMU-352364 https://reactome.org/PathwayBrowser/#/R-MMU-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Mus musculus 35235 R-MMU-352371 https://reactome.org/PathwayBrowser/#/R-MMU-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Mus musculus 35235 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 35235 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 35235 R-MMU-376200 https://reactome.org/PathwayBrowser/#/R-MMU-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Mus musculus 35235 R-MMU-378513 https://reactome.org/PathwayBrowser/#/R-MMU-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Mus musculus 35235 R-MMU-947499 https://reactome.org/PathwayBrowser/#/R-MMU-947499 Exchange of oxygen with sulfur in MoCo IEA Mus musculus 35235 R-MMU-947514 https://reactome.org/PathwayBrowser/#/R-MMU-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Mus musculus 35235 R-MMU-9753944 https://reactome.org/PathwayBrowser/#/R-MMU-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Mus musculus 35235 R-MTU-879319 https://reactome.org/PathwayBrowser/#/R-MTU-879319 glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol TAS Mycobacterium tuberculosis 35235 R-MTU-936642 https://reactome.org/PathwayBrowser/#/R-MTU-936642 deacetylation of O-acetylserine and sulfhydrylation using CysK1 TAS Mycobacterium tuberculosis 35235 R-MTU-936745 https://reactome.org/PathwayBrowser/#/R-MTU-936745 deacetylation of O-acetylserine and sulfhydrylation using CysK2 TAS Mycobacterium tuberculosis 35235 R-MTU-936747 https://reactome.org/PathwayBrowser/#/R-MTU-936747 cleavage of L-cysteine from carrier protein TAS Mycobacterium tuberculosis 35235 R-MTU-937192 https://reactome.org/PathwayBrowser/#/R-MTU-937192 Cysteine from cystathionine and vice versa TAS Mycobacterium tuberculosis 35235 R-PFA-1362408 https://reactome.org/PathwayBrowser/#/R-PFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Plasmodium falciparum 35235 R-PFA-196753 https://reactome.org/PathwayBrowser/#/R-PFA-196753 2xPPCS ligates PPanK with Cys IEA Plasmodium falciparum 35235 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 35235 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 35235 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 35235 R-PFA-947514 https://reactome.org/PathwayBrowser/#/R-PFA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Plasmodium falciparum 35235 R-RNO-1247910 https://reactome.org/PathwayBrowser/#/R-RNO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Rattus norvegicus 35235 R-RNO-1247922 https://reactome.org/PathwayBrowser/#/R-RNO-1247922 GGCT transforms gGluCys to OPRO IEA Rattus norvegicus 35235 R-RNO-1362408 https://reactome.org/PathwayBrowser/#/R-RNO-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Rattus norvegicus 35235 R-RNO-1614583 https://reactome.org/PathwayBrowser/#/R-RNO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Rattus norvegicus 35235 R-RNO-1614591 https://reactome.org/PathwayBrowser/#/R-RNO-1614591 Excess cysteine yields lanthionine and H2S IEA Rattus norvegicus 35235 R-RNO-1614614 https://reactome.org/PathwayBrowser/#/R-RNO-1614614 Cysteine is degraded to serine and H2S IEA Rattus norvegicus 35235 R-RNO-1614645 https://reactome.org/PathwayBrowser/#/R-RNO-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Rattus norvegicus 35235 R-RNO-174367 https://reactome.org/PathwayBrowser/#/R-RNO-174367 GCL ligates L-Glu to L-Cys IEA Rattus norvegicus 35235 R-RNO-196753 https://reactome.org/PathwayBrowser/#/R-RNO-196753 2xPPCS ligates PPanK with Cys IEA Rattus norvegicus 35235 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 35235 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 35235 R-RNO-352347 https://reactome.org/PathwayBrowser/#/R-RNO-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Rattus norvegicus 35235 R-RNO-352354 https://reactome.org/PathwayBrowser/#/R-RNO-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Rattus norvegicus 35235 R-RNO-352364 https://reactome.org/PathwayBrowser/#/R-RNO-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Rattus norvegicus 35235 R-RNO-352371 https://reactome.org/PathwayBrowser/#/R-RNO-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Rattus norvegicus 35235 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 35235 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 35235 R-RNO-376200 https://reactome.org/PathwayBrowser/#/R-RNO-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Rattus norvegicus 35235 R-RNO-378513 https://reactome.org/PathwayBrowser/#/R-RNO-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Rattus norvegicus 35235 R-RNO-9012709 https://reactome.org/PathwayBrowser/#/R-RNO-9012709 Got2:PLXP dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu TAS Rattus norvegicus 35235 R-RNO-947499 https://reactome.org/PathwayBrowser/#/R-RNO-947499 Exchange of oxygen with sulfur in MoCo IEA Rattus norvegicus 35235 R-RNO-947514 https://reactome.org/PathwayBrowser/#/R-RNO-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Rattus norvegicus 35235 R-RNO-9753944 https://reactome.org/PathwayBrowser/#/R-RNO-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Rattus norvegicus 35235 R-SCE-1247910 https://reactome.org/PathwayBrowser/#/R-SCE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Saccharomyces cerevisiae 35235 R-SCE-1362408 https://reactome.org/PathwayBrowser/#/R-SCE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Saccharomyces cerevisiae 35235 R-SCE-1614583 https://reactome.org/PathwayBrowser/#/R-SCE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Saccharomyces cerevisiae 35235 R-SCE-1614591 https://reactome.org/PathwayBrowser/#/R-SCE-1614591 Excess cysteine yields lanthionine and H2S IEA Saccharomyces cerevisiae 35235 R-SCE-1614614 https://reactome.org/PathwayBrowser/#/R-SCE-1614614 Cysteine is degraded to serine and H2S IEA Saccharomyces cerevisiae 35235 R-SCE-196753 https://reactome.org/PathwayBrowser/#/R-SCE-196753 2xPPCS ligates PPanK with Cys IEA Saccharomyces cerevisiae 35235 R-SCE-6787385 https://reactome.org/PathwayBrowser/#/R-SCE-6787385 SLM3 (MTO2, MTU1) transfers a sulfur atom to 5-carboxymethylaminomethyluridine-34 in tRNA TAS Saccharomyces cerevisiae 35235 R-SCE-947514 https://reactome.org/PathwayBrowser/#/R-SCE-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Saccharomyces cerevisiae 35235 R-SPO-1247910 https://reactome.org/PathwayBrowser/#/R-SPO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Schizosaccharomyces pombe 35235 R-SPO-1614583 https://reactome.org/PathwayBrowser/#/R-SPO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Schizosaccharomyces pombe 35235 R-SPO-1614591 https://reactome.org/PathwayBrowser/#/R-SPO-1614591 Excess cysteine yields lanthionine and H2S IEA Schizosaccharomyces pombe 35235 R-SPO-1614614 https://reactome.org/PathwayBrowser/#/R-SPO-1614614 Cysteine is degraded to serine and H2S IEA Schizosaccharomyces pombe 35235 R-SPO-174367 https://reactome.org/PathwayBrowser/#/R-SPO-174367 GCL ligates L-Glu to L-Cys IEA Schizosaccharomyces pombe 35235 R-SPO-196753 https://reactome.org/PathwayBrowser/#/R-SPO-196753 2xPPCS ligates PPanK with Cys IEA Schizosaccharomyces pombe 35235 R-SPO-947514 https://reactome.org/PathwayBrowser/#/R-SPO-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Schizosaccharomyces pombe 35235 R-SSC-1247910 https://reactome.org/PathwayBrowser/#/R-SSC-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Sus scrofa 35235 R-SSC-1247922 https://reactome.org/PathwayBrowser/#/R-SSC-1247922 GGCT transforms gGluCys to OPRO IEA Sus scrofa 35235 R-SSC-1362408 https://reactome.org/PathwayBrowser/#/R-SSC-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Sus scrofa 35235 R-SSC-1614583 https://reactome.org/PathwayBrowser/#/R-SSC-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Sus scrofa 35235 R-SSC-1614591 https://reactome.org/PathwayBrowser/#/R-SSC-1614591 Excess cysteine yields lanthionine and H2S IEA Sus scrofa 35235 R-SSC-1614614 https://reactome.org/PathwayBrowser/#/R-SSC-1614614 Cysteine is degraded to serine and H2S IEA Sus scrofa 35235 R-SSC-1614645 https://reactome.org/PathwayBrowser/#/R-SSC-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Sus scrofa 35235 R-SSC-174367 https://reactome.org/PathwayBrowser/#/R-SSC-174367 GCL ligates L-Glu to L-Cys IEA Sus scrofa 35235 R-SSC-196753 https://reactome.org/PathwayBrowser/#/R-SSC-196753 2xPPCS ligates PPanK with Cys IEA Sus scrofa 35235 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 35235 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 35235 R-SSC-352347 https://reactome.org/PathwayBrowser/#/R-SSC-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Sus scrofa 35235 R-SSC-352354 https://reactome.org/PathwayBrowser/#/R-SSC-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Sus scrofa 35235 R-SSC-352364 https://reactome.org/PathwayBrowser/#/R-SSC-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Sus scrofa 35235 R-SSC-352371 https://reactome.org/PathwayBrowser/#/R-SSC-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Sus scrofa 35235 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 35235 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 35235 R-SSC-376200 https://reactome.org/PathwayBrowser/#/R-SSC-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Sus scrofa 35235 R-SSC-378513 https://reactome.org/PathwayBrowser/#/R-SSC-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Sus scrofa 35235 R-SSC-947499 https://reactome.org/PathwayBrowser/#/R-SSC-947499 Exchange of oxygen with sulfur in MoCo IEA Sus scrofa 35235 R-SSC-947514 https://reactome.org/PathwayBrowser/#/R-SSC-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Sus scrofa 35235 R-SSC-9753944 https://reactome.org/PathwayBrowser/#/R-SSC-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Sus scrofa 35235 R-XTR-1247910 https://reactome.org/PathwayBrowser/#/R-XTR-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Xenopus tropicalis 35235 R-XTR-1247922 https://reactome.org/PathwayBrowser/#/R-XTR-1247922 GGCT transforms gGluCys to OPRO IEA Xenopus tropicalis 35235 R-XTR-1362408 https://reactome.org/PathwayBrowser/#/R-XTR-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Xenopus tropicalis 35235 R-XTR-1614583 https://reactome.org/PathwayBrowser/#/R-XTR-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Xenopus tropicalis 35235 R-XTR-1614591 https://reactome.org/PathwayBrowser/#/R-XTR-1614591 Excess cysteine yields lanthionine and H2S IEA Xenopus tropicalis 35235 R-XTR-1614614 https://reactome.org/PathwayBrowser/#/R-XTR-1614614 Cysteine is degraded to serine and H2S IEA Xenopus tropicalis 35235 R-XTR-1614645 https://reactome.org/PathwayBrowser/#/R-XTR-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Xenopus tropicalis 35235 R-XTR-174367 https://reactome.org/PathwayBrowser/#/R-XTR-174367 GCL ligates L-Glu to L-Cys IEA Xenopus tropicalis 35235 R-XTR-196753 https://reactome.org/PathwayBrowser/#/R-XTR-196753 2xPPCS ligates PPanK with Cys IEA Xenopus tropicalis 35235 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 35235 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 35235 R-XTR-352347 https://reactome.org/PathwayBrowser/#/R-XTR-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Xenopus tropicalis 35235 R-XTR-352354 https://reactome.org/PathwayBrowser/#/R-XTR-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Xenopus tropicalis 35235 R-XTR-352364 https://reactome.org/PathwayBrowser/#/R-XTR-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Xenopus tropicalis 35235 R-XTR-352371 https://reactome.org/PathwayBrowser/#/R-XTR-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Xenopus tropicalis 35235 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 35235 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 35235 R-XTR-376200 https://reactome.org/PathwayBrowser/#/R-XTR-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Xenopus tropicalis 35235 R-XTR-378513 https://reactome.org/PathwayBrowser/#/R-XTR-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Xenopus tropicalis 35235 R-XTR-947514 https://reactome.org/PathwayBrowser/#/R-XTR-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Xenopus tropicalis 35235 R-XTR-9753944 https://reactome.org/PathwayBrowser/#/R-XTR-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Xenopus tropicalis 35341 R-BTA-1606839 https://reactome.org/PathwayBrowser/#/R-BTA-1606839 ARSC hydrolyzes steroid sulfates IEA Bos taurus 35341 R-CFA-1606839 https://reactome.org/PathwayBrowser/#/R-CFA-1606839 ARSC hydrolyzes steroid sulfates IEA Canis familiaris 35341 R-GGA-1606839 https://reactome.org/PathwayBrowser/#/R-GGA-1606839 ARSC hydrolyzes steroid sulfates IEA Gallus gallus 35341 R-HSA-1606839 https://reactome.org/PathwayBrowser/#/R-HSA-1606839 ARSC hydrolyzes steroid sulfates TAS Homo sapiens 35341 R-MMU-1606839 https://reactome.org/PathwayBrowser/#/R-MMU-1606839 ARSC hydrolyzes steroid sulfates IEA Mus musculus 35341 R-RNO-1606839 https://reactome.org/PathwayBrowser/#/R-RNO-1606839 ARSC hydrolyzes steroid sulfates IEA Rattus norvegicus 35341 R-SPO-1606839 https://reactome.org/PathwayBrowser/#/R-SPO-1606839 ARSC hydrolyzes steroid sulfates IEA Schizosaccharomyces pombe 35341 R-SSC-1606839 https://reactome.org/PathwayBrowser/#/R-SSC-1606839 ARSC hydrolyzes steroid sulfates IEA Sus scrofa 35341 R-XTR-1606839 https://reactome.org/PathwayBrowser/#/R-XTR-1606839 ARSC hydrolyzes steroid sulfates IEA Xenopus tropicalis 35366 R-BTA-1482543 https://reactome.org/PathwayBrowser/#/R-BTA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Bos taurus 35366 R-BTA-422048 https://reactome.org/PathwayBrowser/#/R-BTA-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Bos taurus 35366 R-BTA-426032 https://reactome.org/PathwayBrowser/#/R-BTA-426032 DAG is metabolized by DAGL to 2-AG IEA Bos taurus 35366 R-BTA-5694109 https://reactome.org/PathwayBrowser/#/R-BTA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Bos taurus 35366 R-BTA-6810937 https://reactome.org/PathwayBrowser/#/R-BTA-6810937 Lamellar bodies bind the early cornified envelope IEA Bos taurus 35366 R-BTA-6814387 https://reactome.org/PathwayBrowser/#/R-BTA-6814387 CASP14 cleaves filaggrin IEA Bos taurus 35366 R-BTA-6814734 https://reactome.org/PathwayBrowser/#/R-BTA-6814734 CDSN binds the cornified envelope IEA Bos taurus 35366 R-BTA-6814764 https://reactome.org/PathwayBrowser/#/R-BTA-6814764 Plasma membrane resorption IEA Bos taurus 35366 R-BTA-8848484 https://reactome.org/PathwayBrowser/#/R-BTA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Bos taurus 35366 R-BTA-8865667 https://reactome.org/PathwayBrowser/#/R-BTA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Bos taurus 35366 R-CEL-426032 https://reactome.org/PathwayBrowser/#/R-CEL-426032 DAG is metabolized by DAGL to 2-AG IEA Caenorhabditis elegans 35366 R-CEL-8848484 https://reactome.org/PathwayBrowser/#/R-CEL-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Caenorhabditis elegans 35366 R-CFA-1482543 https://reactome.org/PathwayBrowser/#/R-CFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Canis familiaris 35366 R-CFA-422048 https://reactome.org/PathwayBrowser/#/R-CFA-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Canis familiaris 35366 R-CFA-426032 https://reactome.org/PathwayBrowser/#/R-CFA-426032 DAG is metabolized by DAGL to 2-AG IEA Canis familiaris 35366 R-CFA-5694109 https://reactome.org/PathwayBrowser/#/R-CFA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Canis familiaris 35366 R-CFA-6810937 https://reactome.org/PathwayBrowser/#/R-CFA-6810937 Lamellar bodies bind the early cornified envelope IEA Canis familiaris 35366 R-CFA-6814387 https://reactome.org/PathwayBrowser/#/R-CFA-6814387 CASP14 cleaves filaggrin IEA Canis familiaris 35366 R-CFA-6814734 https://reactome.org/PathwayBrowser/#/R-CFA-6814734 CDSN binds the cornified envelope IEA Canis familiaris 35366 R-CFA-6814764 https://reactome.org/PathwayBrowser/#/R-CFA-6814764 Plasma membrane resorption IEA Canis familiaris 35366 R-CFA-8848484 https://reactome.org/PathwayBrowser/#/R-CFA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Canis familiaris 35366 R-CFA-8865667 https://reactome.org/PathwayBrowser/#/R-CFA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Canis familiaris 35366 R-DDI-1482543 https://reactome.org/PathwayBrowser/#/R-DDI-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Dictyostelium discoideum 35366 R-DDI-426032 https://reactome.org/PathwayBrowser/#/R-DDI-426032 DAG is metabolized by DAGL to 2-AG IEA Dictyostelium discoideum 35366 R-DME-426032 https://reactome.org/PathwayBrowser/#/R-DME-426032 DAG is metabolized by DAGL to 2-AG IEA Drosophila melanogaster 35366 R-DME-5694109 https://reactome.org/PathwayBrowser/#/R-DME-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Drosophila melanogaster 35366 R-DME-8848484 https://reactome.org/PathwayBrowser/#/R-DME-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Drosophila melanogaster 35366 R-DRE-1482543 https://reactome.org/PathwayBrowser/#/R-DRE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Danio rerio 35366 R-DRE-422048 https://reactome.org/PathwayBrowser/#/R-DRE-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Danio rerio 35366 R-DRE-426032 https://reactome.org/PathwayBrowser/#/R-DRE-426032 DAG is metabolized by DAGL to 2-AG IEA Danio rerio 35366 R-DRE-5694109 https://reactome.org/PathwayBrowser/#/R-DRE-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Danio rerio 35366 R-DRE-8848484 https://reactome.org/PathwayBrowser/#/R-DRE-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Danio rerio 35366 R-GGA-1482543 https://reactome.org/PathwayBrowser/#/R-GGA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Gallus gallus 35366 R-GGA-422048 https://reactome.org/PathwayBrowser/#/R-GGA-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Gallus gallus 35366 R-GGA-426032 https://reactome.org/PathwayBrowser/#/R-GGA-426032 DAG is metabolized by DAGL to 2-AG IEA Gallus gallus 35366 R-GGA-5694109 https://reactome.org/PathwayBrowser/#/R-GGA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Gallus gallus 35366 R-GGA-8848484 https://reactome.org/PathwayBrowser/#/R-GGA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Gallus gallus 35366 R-GGA-8865667 https://reactome.org/PathwayBrowser/#/R-GGA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Gallus gallus 35366 R-HSA-1482543 https://reactome.org/PathwayBrowser/#/R-HSA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL TAS Homo sapiens 35366 R-HSA-166215 https://reactome.org/PathwayBrowser/#/R-HSA-166215 FA spontaneously flip-flops back to the matrix side TAS Homo sapiens 35366 R-HSA-166219 https://reactome.org/PathwayBrowser/#/R-HSA-166219 FA anion picks up a proton TAS Homo sapiens 35366 R-HSA-166223 https://reactome.org/PathwayBrowser/#/R-HSA-166223 The proton is delivered to the matrix side TAS Homo sapiens 35366 R-HSA-422048 https://reactome.org/PathwayBrowser/#/R-HSA-422048 Acyl Ghrelin and C-Ghrelin are secreted TAS Homo sapiens 35366 R-HSA-426032 https://reactome.org/PathwayBrowser/#/R-HSA-426032 DAG is metabolized by DAGL to 2-AG TAS Homo sapiens 35366 R-HSA-5694109 https://reactome.org/PathwayBrowser/#/R-HSA-5694109 LIPC dimer hydrolyses TAG to DAG and FA TAS Homo sapiens 35366 R-HSA-6810937 https://reactome.org/PathwayBrowser/#/R-HSA-6810937 Lamellar bodies bind the early cornified envelope TAS Homo sapiens 35366 R-HSA-6814298 https://reactome.org/PathwayBrowser/#/R-HSA-6814298 Late envelope proteins bind cornified envelope:CDSN TAS Homo sapiens 35366 R-HSA-6814387 https://reactome.org/PathwayBrowser/#/R-HSA-6814387 CASP14 cleaves filaggrin TAS Homo sapiens 35366 R-HSA-6814734 https://reactome.org/PathwayBrowser/#/R-HSA-6814734 CDSN binds the cornified envelope TAS Homo sapiens 35366 R-HSA-6814764 https://reactome.org/PathwayBrowser/#/R-HSA-6814764 Plasma membrane resorption TAS Homo sapiens 35366 R-HSA-8848484 https://reactome.org/PathwayBrowser/#/R-HSA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane TAS Homo sapiens 35366 R-HSA-8865667 https://reactome.org/PathwayBrowser/#/R-HSA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids TAS Homo sapiens 35366 R-MMU-1482543 https://reactome.org/PathwayBrowser/#/R-MMU-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Mus musculus 35366 R-MMU-422048 https://reactome.org/PathwayBrowser/#/R-MMU-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Mus musculus 35366 R-MMU-426032 https://reactome.org/PathwayBrowser/#/R-MMU-426032 DAG is metabolized by DAGL to 2-AG IEA Mus musculus 35366 R-MMU-5694109 https://reactome.org/PathwayBrowser/#/R-MMU-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Mus musculus 35366 R-MMU-6810937 https://reactome.org/PathwayBrowser/#/R-MMU-6810937 Lamellar bodies bind the early cornified envelope IEA Mus musculus 35366 R-MMU-6814387 https://reactome.org/PathwayBrowser/#/R-MMU-6814387 CASP14 cleaves filaggrin IEA Mus musculus 35366 R-MMU-6814734 https://reactome.org/PathwayBrowser/#/R-MMU-6814734 CDSN binds the cornified envelope IEA Mus musculus 35366 R-MMU-6814764 https://reactome.org/PathwayBrowser/#/R-MMU-6814764 Plasma membrane resorption IEA Mus musculus 35366 R-MMU-8848484 https://reactome.org/PathwayBrowser/#/R-MMU-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Mus musculus 35366 R-MMU-8865667 https://reactome.org/PathwayBrowser/#/R-MMU-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Mus musculus 35366 R-PFA-1482543 https://reactome.org/PathwayBrowser/#/R-PFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Plasmodium falciparum 35366 R-RNO-1482543 https://reactome.org/PathwayBrowser/#/R-RNO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Rattus norvegicus 35366 R-RNO-422048 https://reactome.org/PathwayBrowser/#/R-RNO-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Rattus norvegicus 35366 R-RNO-426032 https://reactome.org/PathwayBrowser/#/R-RNO-426032 DAG is metabolized by DAGL to 2-AG IEA Rattus norvegicus 35366 R-RNO-5694109 https://reactome.org/PathwayBrowser/#/R-RNO-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Rattus norvegicus 35366 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus 35366 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus 35366 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus 35366 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus 35366 R-RNO-8848484 https://reactome.org/PathwayBrowser/#/R-RNO-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Rattus norvegicus 35366 R-RNO-8865667 https://reactome.org/PathwayBrowser/#/R-RNO-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Rattus norvegicus 35366 R-SCE-1482543 https://reactome.org/PathwayBrowser/#/R-SCE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Saccharomyces cerevisiae 35366 R-SCE-8848484 https://reactome.org/PathwayBrowser/#/R-SCE-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Saccharomyces cerevisiae 35366 R-SPO-1482543 https://reactome.org/PathwayBrowser/#/R-SPO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Schizosaccharomyces pombe 35366 R-SPO-8848484 https://reactome.org/PathwayBrowser/#/R-SPO-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Schizosaccharomyces pombe 35366 R-SSC-1482543 https://reactome.org/PathwayBrowser/#/R-SSC-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Sus scrofa 35366 R-SSC-422048 https://reactome.org/PathwayBrowser/#/R-SSC-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Sus scrofa 35366 R-SSC-426032 https://reactome.org/PathwayBrowser/#/R-SSC-426032 DAG is metabolized by DAGL to 2-AG IEA Sus scrofa 35366 R-SSC-5694109 https://reactome.org/PathwayBrowser/#/R-SSC-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Sus scrofa 35366 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa 35366 R-SSC-8848484 https://reactome.org/PathwayBrowser/#/R-SSC-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Sus scrofa 35366 R-SSC-8865667 https://reactome.org/PathwayBrowser/#/R-SSC-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Sus scrofa 35366 R-XTR-1482543 https://reactome.org/PathwayBrowser/#/R-XTR-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Xenopus tropicalis 35366 R-XTR-426032 https://reactome.org/PathwayBrowser/#/R-XTR-426032 DAG is metabolized by DAGL to 2-AG IEA Xenopus tropicalis 35366 R-XTR-5694109 https://reactome.org/PathwayBrowser/#/R-XTR-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Xenopus tropicalis 35366 R-XTR-8848484 https://reactome.org/PathwayBrowser/#/R-XTR-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Xenopus tropicalis 35418 R-BTA-1605723 https://reactome.org/PathwayBrowser/#/R-BTA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Bos taurus 35418 R-BTA-1605724 https://reactome.org/PathwayBrowser/#/R-BTA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Bos taurus 35418 R-BTA-1605768 https://reactome.org/PathwayBrowser/#/R-BTA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Bos taurus 35418 R-BTA-4084982 https://reactome.org/PathwayBrowser/#/R-BTA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Bos taurus 35418 R-BTA-4084989 https://reactome.org/PathwayBrowser/#/R-BTA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Bos taurus 35418 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 35418 R-BTA-4084999 https://reactome.org/PathwayBrowser/#/R-BTA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 35418 R-BTA-4085029 https://reactome.org/PathwayBrowser/#/R-BTA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 35418 R-BTA-4085217 https://reactome.org/PathwayBrowser/#/R-BTA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Bos taurus 35418 R-BTA-428585 https://reactome.org/PathwayBrowser/#/R-BTA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Bos taurus 35418 R-BTA-9638120 https://reactome.org/PathwayBrowser/#/R-BTA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 35418 R-CEL-428585 https://reactome.org/PathwayBrowser/#/R-CEL-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Caenorhabditis elegans 35418 R-CFA-1605723 https://reactome.org/PathwayBrowser/#/R-CFA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Canis familiaris 35418 R-CFA-1605724 https://reactome.org/PathwayBrowser/#/R-CFA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Canis familiaris 35418 R-CFA-1605768 https://reactome.org/PathwayBrowser/#/R-CFA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Canis familiaris 35418 R-CFA-4084982 https://reactome.org/PathwayBrowser/#/R-CFA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Canis familiaris 35418 R-CFA-4084989 https://reactome.org/PathwayBrowser/#/R-CFA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Canis familiaris 35418 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 35418 R-CFA-4084999 https://reactome.org/PathwayBrowser/#/R-CFA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 35418 R-CFA-4085029 https://reactome.org/PathwayBrowser/#/R-CFA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 35418 R-CFA-4085217 https://reactome.org/PathwayBrowser/#/R-CFA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Canis familiaris 35418 R-CFA-428585 https://reactome.org/PathwayBrowser/#/R-CFA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Canis familiaris 35418 R-CFA-9638120 https://reactome.org/PathwayBrowser/#/R-CFA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 35418 R-DDI-428585 https://reactome.org/PathwayBrowser/#/R-DDI-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Dictyostelium discoideum 35418 R-DME-4084989 https://reactome.org/PathwayBrowser/#/R-DME-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Drosophila melanogaster 35418 R-DME-428585 https://reactome.org/PathwayBrowser/#/R-DME-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Drosophila melanogaster 35418 R-DRE-1605723 https://reactome.org/PathwayBrowser/#/R-DRE-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Danio rerio 35418 R-DRE-1605768 https://reactome.org/PathwayBrowser/#/R-DRE-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Danio rerio 35418 R-DRE-4084982 https://reactome.org/PathwayBrowser/#/R-DRE-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Danio rerio 35418 R-DRE-4084989 https://reactome.org/PathwayBrowser/#/R-DRE-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Danio rerio 35418 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 35418 R-DRE-4085029 https://reactome.org/PathwayBrowser/#/R-DRE-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 35418 R-DRE-4085217 https://reactome.org/PathwayBrowser/#/R-DRE-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Danio rerio 35418 R-DRE-428585 https://reactome.org/PathwayBrowser/#/R-DRE-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Danio rerio 35418 R-GGA-1605723 https://reactome.org/PathwayBrowser/#/R-GGA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Gallus gallus 35418 R-GGA-1605724 https://reactome.org/PathwayBrowser/#/R-GGA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Gallus gallus 35418 R-GGA-1605768 https://reactome.org/PathwayBrowser/#/R-GGA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Gallus gallus 35418 R-GGA-4084982 https://reactome.org/PathwayBrowser/#/R-GGA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Gallus gallus 35418 R-GGA-4084989 https://reactome.org/PathwayBrowser/#/R-GGA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Gallus gallus 35418 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 35418 R-GGA-4085029 https://reactome.org/PathwayBrowser/#/R-GGA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 35418 R-GGA-4085217 https://reactome.org/PathwayBrowser/#/R-GGA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Gallus gallus 35418 R-GGA-428585 https://reactome.org/PathwayBrowser/#/R-GGA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Gallus gallus 35418 R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus 35418 R-HSA-1605723 https://reactome.org/PathwayBrowser/#/R-HSA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) TAS Homo sapiens 35418 R-HSA-1605724 https://reactome.org/PathwayBrowser/#/R-HSA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE TAS Homo sapiens 35418 R-HSA-1605768 https://reactome.org/PathwayBrowser/#/R-HSA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) TAS Homo sapiens 35418 R-HSA-4084982 https://reactome.org/PathwayBrowser/#/R-HSA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac TAS Homo sapiens 35418 R-HSA-4084989 https://reactome.org/PathwayBrowser/#/R-HSA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac TAS Homo sapiens 35418 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 35418 R-HSA-4084999 https://reactome.org/PathwayBrowser/#/R-HSA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 35418 R-HSA-4085020 https://reactome.org/PathwayBrowser/#/R-HSA-4085020 Cytosolic Neu5Ac translocates to nucleus TAS Homo sapiens 35418 R-HSA-4085029 https://reactome.org/PathwayBrowser/#/R-HSA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 35418 R-HSA-4085217 https://reactome.org/PathwayBrowser/#/R-HSA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate TAS Homo sapiens 35418 R-HSA-428585 https://reactome.org/PathwayBrowser/#/R-HSA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol TAS Homo sapiens 35418 R-HSA-5624239 https://reactome.org/PathwayBrowser/#/R-HSA-5624239 Defective SLC17A5 does not cotransport Neu5Ac, H+ from lysosomal lumen to cytosol TAS Homo sapiens 35418 R-HSA-9638120 https://reactome.org/PathwayBrowser/#/R-HSA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 35418 R-MMU-1605723 https://reactome.org/PathwayBrowser/#/R-MMU-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Mus musculus 35418 R-MMU-1605724 https://reactome.org/PathwayBrowser/#/R-MMU-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Mus musculus 35418 R-MMU-1605768 https://reactome.org/PathwayBrowser/#/R-MMU-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Mus musculus 35418 R-MMU-4084982 https://reactome.org/PathwayBrowser/#/R-MMU-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Mus musculus 35418 R-MMU-4084989 https://reactome.org/PathwayBrowser/#/R-MMU-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Mus musculus 35418 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 35418 R-MMU-4084999 https://reactome.org/PathwayBrowser/#/R-MMU-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 35418 R-MMU-4085029 https://reactome.org/PathwayBrowser/#/R-MMU-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 35418 R-MMU-4085217 https://reactome.org/PathwayBrowser/#/R-MMU-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Mus musculus 35418 R-MMU-428585 https://reactome.org/PathwayBrowser/#/R-MMU-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Mus musculus 35418 R-MMU-9638120 https://reactome.org/PathwayBrowser/#/R-MMU-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 35418 R-RNO-1605723 https://reactome.org/PathwayBrowser/#/R-RNO-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Rattus norvegicus 35418 R-RNO-1605724 https://reactome.org/PathwayBrowser/#/R-RNO-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Rattus norvegicus 35418 R-RNO-1605768 https://reactome.org/PathwayBrowser/#/R-RNO-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Rattus norvegicus 35418 R-RNO-4084982 https://reactome.org/PathwayBrowser/#/R-RNO-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Rattus norvegicus 35418 R-RNO-4084989 https://reactome.org/PathwayBrowser/#/R-RNO-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Rattus norvegicus 35418 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 35418 R-RNO-4084999 https://reactome.org/PathwayBrowser/#/R-RNO-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 35418 R-RNO-4085029 https://reactome.org/PathwayBrowser/#/R-RNO-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 35418 R-RNO-4085217 https://reactome.org/PathwayBrowser/#/R-RNO-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Rattus norvegicus 35418 R-RNO-9638120 https://reactome.org/PathwayBrowser/#/R-RNO-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 35418 R-SSC-1605723 https://reactome.org/PathwayBrowser/#/R-SSC-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Sus scrofa 35418 R-SSC-1605724 https://reactome.org/PathwayBrowser/#/R-SSC-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Sus scrofa 35418 R-SSC-1605768 https://reactome.org/PathwayBrowser/#/R-SSC-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Sus scrofa 35418 R-SSC-4084982 https://reactome.org/PathwayBrowser/#/R-SSC-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Sus scrofa 35418 R-SSC-4084989 https://reactome.org/PathwayBrowser/#/R-SSC-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Sus scrofa 35418 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 35418 R-SSC-4084999 https://reactome.org/PathwayBrowser/#/R-SSC-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 35418 R-SSC-4085029 https://reactome.org/PathwayBrowser/#/R-SSC-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 35418 R-SSC-4085217 https://reactome.org/PathwayBrowser/#/R-SSC-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Sus scrofa 35418 R-SSC-428585 https://reactome.org/PathwayBrowser/#/R-SSC-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Sus scrofa 35418 R-SSC-9638120 https://reactome.org/PathwayBrowser/#/R-SSC-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 35418 R-XTR-1605723 https://reactome.org/PathwayBrowser/#/R-XTR-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Xenopus tropicalis 35418 R-XTR-1605768 https://reactome.org/PathwayBrowser/#/R-XTR-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Xenopus tropicalis 35418 R-XTR-4084982 https://reactome.org/PathwayBrowser/#/R-XTR-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Xenopus tropicalis 35418 R-XTR-4084989 https://reactome.org/PathwayBrowser/#/R-XTR-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Xenopus tropicalis 35418 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 35418 R-XTR-4084999 https://reactome.org/PathwayBrowser/#/R-XTR-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 35418 R-XTR-4085029 https://reactome.org/PathwayBrowser/#/R-XTR-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 35418 R-XTR-4085217 https://reactome.org/PathwayBrowser/#/R-XTR-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Xenopus tropicalis 35418 R-XTR-428585 https://reactome.org/PathwayBrowser/#/R-XTR-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Xenopus tropicalis 35418 R-XTR-9638120 https://reactome.org/PathwayBrowser/#/R-XTR-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 35419 R-BTA-176494 https://reactome.org/PathwayBrowser/#/R-BTA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Bos taurus 35419 R-CFA-176494 https://reactome.org/PathwayBrowser/#/R-CFA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Canis familiaris 35419 R-DME-176494 https://reactome.org/PathwayBrowser/#/R-DME-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Drosophila melanogaster 35419 R-DRE-176494 https://reactome.org/PathwayBrowser/#/R-DRE-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Danio rerio 35419 R-GGA-176494 https://reactome.org/PathwayBrowser/#/R-GGA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Gallus gallus 35419 R-HSA-176494 https://reactome.org/PathwayBrowser/#/R-HSA-176494 SULTs transfer (SO4)2- group to 27HCHOL TAS Homo sapiens 35419 R-MMU-176494 https://reactome.org/PathwayBrowser/#/R-MMU-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Mus musculus 35419 R-RNO-176494 https://reactome.org/PathwayBrowser/#/R-RNO-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Rattus norvegicus 35419 R-SSC-176494 https://reactome.org/PathwayBrowser/#/R-SSC-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Sus scrofa 35419 R-XTR-176494 https://reactome.org/PathwayBrowser/#/R-XTR-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Xenopus tropicalis 35420 R-BTA-176517 https://reactome.org/PathwayBrowser/#/R-BTA-176517 SULTs transfer (SO4)2- group to PREG IEA Bos taurus 35420 R-CFA-176517 https://reactome.org/PathwayBrowser/#/R-CFA-176517 SULTs transfer (SO4)2- group to PREG IEA Canis familiaris 35420 R-DME-176517 https://reactome.org/PathwayBrowser/#/R-DME-176517 SULTs transfer (SO4)2- group to PREG IEA Drosophila melanogaster 35420 R-DRE-176517 https://reactome.org/PathwayBrowser/#/R-DRE-176517 SULTs transfer (SO4)2- group to PREG IEA Danio rerio 35420 R-GGA-176517 https://reactome.org/PathwayBrowser/#/R-GGA-176517 SULTs transfer (SO4)2- group to PREG IEA Gallus gallus 35420 R-HSA-176517 https://reactome.org/PathwayBrowser/#/R-HSA-176517 SULTs transfer (SO4)2- group to PREG TAS Homo sapiens 35420 R-MMU-176517 https://reactome.org/PathwayBrowser/#/R-MMU-176517 SULTs transfer (SO4)2- group to PREG IEA Mus musculus 35420 R-RNO-176517 https://reactome.org/PathwayBrowser/#/R-RNO-176517 SULTs transfer (SO4)2- group to PREG IEA Rattus norvegicus 35420 R-SSC-176517 https://reactome.org/PathwayBrowser/#/R-SSC-176517 SULTs transfer (SO4)2- group to PREG IEA Sus scrofa 35420 R-XTR-176517 https://reactome.org/PathwayBrowser/#/R-XTR-176517 SULTs transfer (SO4)2- group to PREG IEA Xenopus tropicalis 35422 R-BTA-176646 https://reactome.org/PathwayBrowser/#/R-BTA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Bos taurus 35422 R-CFA-176646 https://reactome.org/PathwayBrowser/#/R-CFA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Canis familiaris 35422 R-DME-176646 https://reactome.org/PathwayBrowser/#/R-DME-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Drosophila melanogaster 35422 R-DRE-176646 https://reactome.org/PathwayBrowser/#/R-DRE-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Danio rerio 35422 R-GGA-176646 https://reactome.org/PathwayBrowser/#/R-GGA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Gallus gallus 35422 R-HSA-176646 https://reactome.org/PathwayBrowser/#/R-HSA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP TAS Homo sapiens 35422 R-MMU-176646 https://reactome.org/PathwayBrowser/#/R-MMU-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Mus musculus 35422 R-RNO-176646 https://reactome.org/PathwayBrowser/#/R-RNO-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Rattus norvegicus 35422 R-SSC-176646 https://reactome.org/PathwayBrowser/#/R-SSC-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Sus scrofa 35422 R-XTR-176646 https://reactome.org/PathwayBrowser/#/R-XTR-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Xenopus tropicalis 35424 R-BTA-176669 https://reactome.org/PathwayBrowser/#/R-BTA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Bos taurus 35424 R-CFA-176669 https://reactome.org/PathwayBrowser/#/R-CFA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Canis familiaris 35424 R-DME-176669 https://reactome.org/PathwayBrowser/#/R-DME-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Drosophila melanogaster 35424 R-DRE-176669 https://reactome.org/PathwayBrowser/#/R-DRE-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Danio rerio 35424 R-GGA-176669 https://reactome.org/PathwayBrowser/#/R-GGA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Gallus gallus 35424 R-HSA-176669 https://reactome.org/PathwayBrowser/#/R-HSA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP TAS Homo sapiens 35424 R-MMU-176669 https://reactome.org/PathwayBrowser/#/R-MMU-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Mus musculus 35424 R-RNO-176669 https://reactome.org/PathwayBrowser/#/R-RNO-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Rattus norvegicus 35424 R-SSC-176669 https://reactome.org/PathwayBrowser/#/R-SSC-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Sus scrofa 35424 R-XTR-176669 https://reactome.org/PathwayBrowser/#/R-XTR-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Xenopus tropicalis 35430 R-BTA-176474 https://reactome.org/PathwayBrowser/#/R-BTA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Bos taurus 35430 R-CEL-176474 https://reactome.org/PathwayBrowser/#/R-CEL-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Caenorhabditis elegans 35430 R-CFA-176474 https://reactome.org/PathwayBrowser/#/R-CFA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Canis familiaris 35430 R-DME-176474 https://reactome.org/PathwayBrowser/#/R-DME-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Drosophila melanogaster 35430 R-DRE-176474 https://reactome.org/PathwayBrowser/#/R-DRE-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Danio rerio 35430 R-GGA-176474 https://reactome.org/PathwayBrowser/#/R-GGA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Gallus gallus 35430 R-HSA-176474 https://reactome.org/PathwayBrowser/#/R-HSA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP TAS Homo sapiens 35430 R-MMU-176474 https://reactome.org/PathwayBrowser/#/R-MMU-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Mus musculus 35430 R-RNO-176474 https://reactome.org/PathwayBrowser/#/R-RNO-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Rattus norvegicus 35430 R-SSC-176474 https://reactome.org/PathwayBrowser/#/R-SSC-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Sus scrofa 35430 R-XTR-176474 https://reactome.org/PathwayBrowser/#/R-XTR-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Xenopus tropicalis 35431 R-BTA-176474 https://reactome.org/PathwayBrowser/#/R-BTA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Bos taurus 35431 R-CEL-176474 https://reactome.org/PathwayBrowser/#/R-CEL-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Caenorhabditis elegans 35431 R-CFA-176474 https://reactome.org/PathwayBrowser/#/R-CFA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Canis familiaris 35431 R-DME-176474 https://reactome.org/PathwayBrowser/#/R-DME-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Drosophila melanogaster 35431 R-DRE-176474 https://reactome.org/PathwayBrowser/#/R-DRE-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Danio rerio 35431 R-GGA-176474 https://reactome.org/PathwayBrowser/#/R-GGA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Gallus gallus 35431 R-HSA-176474 https://reactome.org/PathwayBrowser/#/R-HSA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP TAS Homo sapiens 35431 R-MMU-176474 https://reactome.org/PathwayBrowser/#/R-MMU-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Mus musculus 35431 R-RNO-176474 https://reactome.org/PathwayBrowser/#/R-RNO-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Rattus norvegicus 35431 R-SSC-176474 https://reactome.org/PathwayBrowser/#/R-SSC-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Sus scrofa 35431 R-XTR-176474 https://reactome.org/PathwayBrowser/#/R-XTR-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Xenopus tropicalis 35432 R-BTA-176585 https://reactome.org/PathwayBrowser/#/R-BTA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Bos taurus 35432 R-CEL-176585 https://reactome.org/PathwayBrowser/#/R-CEL-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Caenorhabditis elegans 35432 R-CFA-176585 https://reactome.org/PathwayBrowser/#/R-CFA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Canis familiaris 35432 R-DME-176585 https://reactome.org/PathwayBrowser/#/R-DME-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Drosophila melanogaster 35432 R-DRE-176585 https://reactome.org/PathwayBrowser/#/R-DRE-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Danio rerio 35432 R-GGA-176585 https://reactome.org/PathwayBrowser/#/R-GGA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Gallus gallus 35432 R-HSA-176585 https://reactome.org/PathwayBrowser/#/R-HSA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP TAS Homo sapiens 35432 R-MMU-176585 https://reactome.org/PathwayBrowser/#/R-MMU-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Mus musculus 35432 R-RNO-176585 https://reactome.org/PathwayBrowser/#/R-RNO-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Rattus norvegicus 35432 R-SSC-176585 https://reactome.org/PathwayBrowser/#/R-SSC-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Sus scrofa 35432 R-XTR-176585 https://reactome.org/PathwayBrowser/#/R-XTR-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Xenopus tropicalis 35475 R-BTA-2671885 https://reactome.org/PathwayBrowser/#/R-BTA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Bos taurus 35475 R-CEL-2671885 https://reactome.org/PathwayBrowser/#/R-CEL-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Caenorhabditis elegans 35475 R-CFA-2671885 https://reactome.org/PathwayBrowser/#/R-CFA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Canis familiaris 35475 R-DME-2671885 https://reactome.org/PathwayBrowser/#/R-DME-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Drosophila melanogaster 35475 R-DRE-2671885 https://reactome.org/PathwayBrowser/#/R-DRE-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Danio rerio 35475 R-GGA-2671885 https://reactome.org/PathwayBrowser/#/R-GGA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Gallus gallus 35475 R-HSA-2671885 https://reactome.org/PathwayBrowser/#/R-HSA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol TAS Homo sapiens 35475 R-MMU-2671885 https://reactome.org/PathwayBrowser/#/R-MMU-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Mus musculus 35475 R-RNO-2671885 https://reactome.org/PathwayBrowser/#/R-RNO-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Rattus norvegicus 35475 R-SSC-2671885 https://reactome.org/PathwayBrowser/#/R-SSC-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Sus scrofa 35475 R-XTR-2671885 https://reactome.org/PathwayBrowser/#/R-XTR-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Xenopus tropicalis 356416 R-BTA-189439 https://reactome.org/PathwayBrowser/#/R-BTA-189439 ALAD condenses 2 dALAs to form PBG IEA Bos taurus 356416 R-BTA-189442 https://reactome.org/PathwayBrowser/#/R-BTA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Bos taurus 356416 R-CFA-189439 https://reactome.org/PathwayBrowser/#/R-CFA-189439 ALAD condenses 2 dALAs to form PBG IEA Canis familiaris 356416 R-CFA-189442 https://reactome.org/PathwayBrowser/#/R-CFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Canis familiaris 356416 R-DDI-189439 https://reactome.org/PathwayBrowser/#/R-DDI-189439 ALAD condenses 2 dALAs to form PBG IEA Dictyostelium discoideum 356416 R-DDI-189442 https://reactome.org/PathwayBrowser/#/R-DDI-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Dictyostelium discoideum 356416 R-DME-189439 https://reactome.org/PathwayBrowser/#/R-DME-189439 ALAD condenses 2 dALAs to form PBG IEA Drosophila melanogaster 356416 R-DME-189442 https://reactome.org/PathwayBrowser/#/R-DME-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Drosophila melanogaster 356416 R-DRE-189439 https://reactome.org/PathwayBrowser/#/R-DRE-189439 ALAD condenses 2 dALAs to form PBG IEA Danio rerio 356416 R-DRE-189442 https://reactome.org/PathwayBrowser/#/R-DRE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Danio rerio 356416 R-GGA-189439 https://reactome.org/PathwayBrowser/#/R-GGA-189439 ALAD condenses 2 dALAs to form PBG IEA Gallus gallus 356416 R-GGA-189442 https://reactome.org/PathwayBrowser/#/R-GGA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Gallus gallus 356416 R-GGA-421472 https://reactome.org/PathwayBrowser/#/R-GGA-421472 2 delta-aminolevulinate => porphobilinogen + 2 H2O IEA Gallus gallus 356416 R-GGA-421493 https://reactome.org/PathwayBrowser/#/R-GGA-421493 succinyl-CoA + glycine => delta-aminolevulinate + CoA SH + CO2 TAS Gallus gallus 356416 R-GGA-421517 https://reactome.org/PathwayBrowser/#/R-GGA-421517 Transport of delta-aminolevulinate from the mitochondrial matrix to the cytosol TAS Gallus gallus 356416 R-HSA-189439 https://reactome.org/PathwayBrowser/#/R-HSA-189439 ALAD condenses 2 dALAs to form PBG TAS Homo sapiens 356416 R-HSA-189442 https://reactome.org/PathwayBrowser/#/R-HSA-189442 ALAS condenses SUCC-CoA and Gly to form dALA TAS Homo sapiens 356416 R-HSA-189456 https://reactome.org/PathwayBrowser/#/R-HSA-189456 Mitochondrial dALA translocates to cytosol TAS Homo sapiens 356416 R-MMU-189439 https://reactome.org/PathwayBrowser/#/R-MMU-189439 ALAD condenses 2 dALAs to form PBG IEA Mus musculus 356416 R-MMU-189442 https://reactome.org/PathwayBrowser/#/R-MMU-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Mus musculus 356416 R-PFA-189439 https://reactome.org/PathwayBrowser/#/R-PFA-189439 ALAD condenses 2 dALAs to form PBG IEA Plasmodium falciparum 356416 R-PFA-189442 https://reactome.org/PathwayBrowser/#/R-PFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Plasmodium falciparum 356416 R-RNO-189439 https://reactome.org/PathwayBrowser/#/R-RNO-189439 ALAD condenses 2 dALAs to form PBG IEA Rattus norvegicus 356416 R-RNO-189442 https://reactome.org/PathwayBrowser/#/R-RNO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Rattus norvegicus 356416 R-SCE-189439 https://reactome.org/PathwayBrowser/#/R-SCE-189439 ALAD condenses 2 dALAs to form PBG IEA Saccharomyces cerevisiae 356416 R-SCE-189442 https://reactome.org/PathwayBrowser/#/R-SCE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Saccharomyces cerevisiae 356416 R-SPO-189439 https://reactome.org/PathwayBrowser/#/R-SPO-189439 ALAD condenses 2 dALAs to form PBG IEA Schizosaccharomyces pombe 356416 R-SPO-189442 https://reactome.org/PathwayBrowser/#/R-SPO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Schizosaccharomyces pombe 356416 R-SSC-189439 https://reactome.org/PathwayBrowser/#/R-SSC-189439 ALAD condenses 2 dALAs to form PBG IEA Sus scrofa 356416 R-SSC-189442 https://reactome.org/PathwayBrowser/#/R-SSC-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Sus scrofa 356416 R-XTR-189439 https://reactome.org/PathwayBrowser/#/R-XTR-189439 ALAD condenses 2 dALAs to form PBG IEA Xenopus tropicalis 356416 R-XTR-189442 https://reactome.org/PathwayBrowser/#/R-XTR-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Xenopus tropicalis 35746 R-BTA-5696119 https://reactome.org/PathwayBrowser/#/R-BTA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Bos taurus 35746 R-BTA-8874435 https://reactome.org/PathwayBrowser/#/R-BTA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Bos taurus 35746 R-CEL-5696119 https://reactome.org/PathwayBrowser/#/R-CEL-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Caenorhabditis elegans 35746 R-CEL-8874435 https://reactome.org/PathwayBrowser/#/R-CEL-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Caenorhabditis elegans 35746 R-CFA-5696119 https://reactome.org/PathwayBrowser/#/R-CFA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Canis familiaris 35746 R-CFA-8874435 https://reactome.org/PathwayBrowser/#/R-CFA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Canis familiaris 35746 R-DDI-5696119 https://reactome.org/PathwayBrowser/#/R-DDI-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Dictyostelium discoideum 35746 R-DDI-8874435 https://reactome.org/PathwayBrowser/#/R-DDI-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Dictyostelium discoideum 35746 R-DME-8874435 https://reactome.org/PathwayBrowser/#/R-DME-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Drosophila melanogaster 35746 R-DRE-5696119 https://reactome.org/PathwayBrowser/#/R-DRE-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Danio rerio 35746 R-DRE-8874435 https://reactome.org/PathwayBrowser/#/R-DRE-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Danio rerio 35746 R-GGA-5696119 https://reactome.org/PathwayBrowser/#/R-GGA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Gallus gallus 35746 R-HSA-5696119 https://reactome.org/PathwayBrowser/#/R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol TAS Homo sapiens 35746 R-HSA-8874435 https://reactome.org/PathwayBrowser/#/R-HSA-8874435 THEM86B hydrolyses PMCHO, PMETAM TAS Homo sapiens 35746 R-MMU-5696119 https://reactome.org/PathwayBrowser/#/R-MMU-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Mus musculus 35746 R-MMU-8874435 https://reactome.org/PathwayBrowser/#/R-MMU-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Mus musculus 35746 R-RNO-5696119 https://reactome.org/PathwayBrowser/#/R-RNO-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Rattus norvegicus 35746 R-RNO-8874435 https://reactome.org/PathwayBrowser/#/R-RNO-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Rattus norvegicus 35746 R-SSC-5696119 https://reactome.org/PathwayBrowser/#/R-SSC-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Sus scrofa 35746 R-SSC-8874435 https://reactome.org/PathwayBrowser/#/R-SSC-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Sus scrofa 35746 R-XTR-5696119 https://reactome.org/PathwayBrowser/#/R-XTR-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Xenopus tropicalis 35746 R-XTR-8874435 https://reactome.org/PathwayBrowser/#/R-XTR-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Xenopus tropicalis 35785 R-BTA-428123 https://reactome.org/PathwayBrowser/#/R-BTA-428123 KDSR reduces 3-ketosphingoid IEA Bos taurus 35785 R-BTA-428185 https://reactome.org/PathwayBrowser/#/R-BTA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Bos taurus 35785 R-CEL-428123 https://reactome.org/PathwayBrowser/#/R-CEL-428123 KDSR reduces 3-ketosphingoid IEA Caenorhabditis elegans 35785 R-CEL-428185 https://reactome.org/PathwayBrowser/#/R-CEL-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Caenorhabditis elegans 35785 R-CFA-428123 https://reactome.org/PathwayBrowser/#/R-CFA-428123 KDSR reduces 3-ketosphingoid IEA Canis familiaris 35785 R-CFA-428185 https://reactome.org/PathwayBrowser/#/R-CFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Canis familiaris 35785 R-DDI-428123 https://reactome.org/PathwayBrowser/#/R-DDI-428123 KDSR reduces 3-ketosphingoid IEA Dictyostelium discoideum 35785 R-DDI-428185 https://reactome.org/PathwayBrowser/#/R-DDI-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Dictyostelium discoideum 35785 R-DME-428123 https://reactome.org/PathwayBrowser/#/R-DME-428123 KDSR reduces 3-ketosphingoid IEA Drosophila melanogaster 35785 R-DME-428185 https://reactome.org/PathwayBrowser/#/R-DME-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Drosophila melanogaster 35785 R-DRE-428185 https://reactome.org/PathwayBrowser/#/R-DRE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Danio rerio 35785 R-GGA-428185 https://reactome.org/PathwayBrowser/#/R-GGA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Gallus gallus 35785 R-HSA-428123 https://reactome.org/PathwayBrowser/#/R-HSA-428123 KDSR reduces 3-ketosphingoid TAS Homo sapiens 35785 R-HSA-428185 https://reactome.org/PathwayBrowser/#/R-HSA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid TAS Homo sapiens 35785 R-MMU-428123 https://reactome.org/PathwayBrowser/#/R-MMU-428123 KDSR reduces 3-ketosphingoid IEA Mus musculus 35785 R-MMU-428185 https://reactome.org/PathwayBrowser/#/R-MMU-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Mus musculus 35785 R-PFA-428123 https://reactome.org/PathwayBrowser/#/R-PFA-428123 KDSR reduces 3-ketosphingoid IEA Plasmodium falciparum 35785 R-PFA-428185 https://reactome.org/PathwayBrowser/#/R-PFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Plasmodium falciparum 35785 R-RNO-428123 https://reactome.org/PathwayBrowser/#/R-RNO-428123 KDSR reduces 3-ketosphingoid IEA Rattus norvegicus 35785 R-RNO-428185 https://reactome.org/PathwayBrowser/#/R-RNO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Rattus norvegicus 35785 R-SCE-428123 https://reactome.org/PathwayBrowser/#/R-SCE-428123 KDSR reduces 3-ketosphingoid IEA Saccharomyces cerevisiae 35785 R-SCE-428185 https://reactome.org/PathwayBrowser/#/R-SCE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Saccharomyces cerevisiae 35785 R-SPO-428123 https://reactome.org/PathwayBrowser/#/R-SPO-428123 KDSR reduces 3-ketosphingoid IEA Schizosaccharomyces pombe 35785 R-SPO-428185 https://reactome.org/PathwayBrowser/#/R-SPO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Schizosaccharomyces pombe 35785 R-SSC-428123 https://reactome.org/PathwayBrowser/#/R-SSC-428123 KDSR reduces 3-ketosphingoid IEA Sus scrofa 35785 R-SSC-428185 https://reactome.org/PathwayBrowser/#/R-SSC-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Sus scrofa 35785 R-XTR-428123 https://reactome.org/PathwayBrowser/#/R-XTR-428123 KDSR reduces 3-ketosphingoid IEA Xenopus tropicalis 35785 R-XTR-428185 https://reactome.org/PathwayBrowser/#/R-XTR-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Xenopus tropicalis 35828 R-BTA-5661230 https://reactome.org/PathwayBrowser/#/R-BTA-5661230 MT1A binds arsenic IEA Bos taurus 35828 R-CFA-5661230 https://reactome.org/PathwayBrowser/#/R-CFA-5661230 MT1A binds arsenic IEA Canis familiaris 35828 R-DRE-5661230 https://reactome.org/PathwayBrowser/#/R-DRE-5661230 MT1A binds arsenic IEA Danio rerio 35828 R-GGA-5661230 https://reactome.org/PathwayBrowser/#/R-GGA-5661230 MT1A binds arsenic IEA Gallus gallus 35828 R-HSA-5661230 https://reactome.org/PathwayBrowser/#/R-HSA-5661230 MT1A binds arsenic TAS Homo sapiens 35828 R-MMU-5661230 https://reactome.org/PathwayBrowser/#/R-MMU-5661230 MT1A binds arsenic IEA Mus musculus 35828 R-RNO-5661230 https://reactome.org/PathwayBrowser/#/R-RNO-5661230 MT1A binds arsenic IEA Rattus norvegicus 35828 R-SSC-5661230 https://reactome.org/PathwayBrowser/#/R-SSC-5661230 MT1A binds arsenic IEA Sus scrofa 35854 R-BTA-6784959 https://reactome.org/PathwayBrowser/#/R-BTA-6784959 BPHL hydrolyses VACV to ACV IEA Bos taurus 35854 R-CEL-6784959 https://reactome.org/PathwayBrowser/#/R-CEL-6784959 BPHL hydrolyses VACV to ACV IEA Caenorhabditis elegans 35854 R-CFA-6784959 https://reactome.org/PathwayBrowser/#/R-CFA-6784959 BPHL hydrolyses VACV to ACV IEA Canis familiaris 35854 R-DME-6784959 https://reactome.org/PathwayBrowser/#/R-DME-6784959 BPHL hydrolyses VACV to ACV IEA Drosophila melanogaster 35854 R-GGA-6784959 https://reactome.org/PathwayBrowser/#/R-GGA-6784959 BPHL hydrolyses VACV to ACV IEA Gallus gallus 35854 R-HSA-6784959 https://reactome.org/PathwayBrowser/#/R-HSA-6784959 BPHL hydrolyses VACV to ACV TAS Homo sapiens 35854 R-MMU-6784959 https://reactome.org/PathwayBrowser/#/R-MMU-6784959 BPHL hydrolyses VACV to ACV IEA Mus musculus 35854 R-RNO-6784959 https://reactome.org/PathwayBrowser/#/R-RNO-6784959 BPHL hydrolyses VACV to ACV IEA Rattus norvegicus 35854 R-SSC-6784959 https://reactome.org/PathwayBrowser/#/R-SSC-6784959 BPHL hydrolyses VACV to ACV IEA Sus scrofa 35896 R-BTA-176059 https://reactome.org/PathwayBrowser/#/R-BTA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Bos taurus 35896 R-CFA-176059 https://reactome.org/PathwayBrowser/#/R-CFA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Canis familiaris 35896 R-DDI-176059 https://reactome.org/PathwayBrowser/#/R-DDI-176059 GST trimers transfer GS from GSH to luminal substrates IEA Dictyostelium discoideum 35896 R-DME-176059 https://reactome.org/PathwayBrowser/#/R-DME-176059 GST trimers transfer GS from GSH to luminal substrates IEA Drosophila melanogaster 35896 R-DRE-176059 https://reactome.org/PathwayBrowser/#/R-DRE-176059 GST trimers transfer GS from GSH to luminal substrates IEA Danio rerio 35896 R-GGA-176059 https://reactome.org/PathwayBrowser/#/R-GGA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Gallus gallus 35896 R-HSA-176059 https://reactome.org/PathwayBrowser/#/R-HSA-176059 GST trimers transfer GS from GSH to luminal substrates TAS Homo sapiens 35896 R-MMU-176059 https://reactome.org/PathwayBrowser/#/R-MMU-176059 GST trimers transfer GS from GSH to luminal substrates IEA Mus musculus 35896 R-RNO-176059 https://reactome.org/PathwayBrowser/#/R-RNO-176059 GST trimers transfer GS from GSH to luminal substrates IEA Rattus norvegicus 35896 R-SSC-176059 https://reactome.org/PathwayBrowser/#/R-SSC-176059 GST trimers transfer GS from GSH to luminal substrates IEA Sus scrofa 35896 R-XTR-176059 https://reactome.org/PathwayBrowser/#/R-XTR-176059 GST trimers transfer GS from GSH to luminal substrates IEA Xenopus tropicalis 36005 R-BTA-6786239 https://reactome.org/PathwayBrowser/#/R-BTA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Bos taurus 36005 R-CEL-6786239 https://reactome.org/PathwayBrowser/#/R-CEL-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Caenorhabditis elegans 36005 R-CFA-6786239 https://reactome.org/PathwayBrowser/#/R-CFA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Canis familiaris 36005 R-DME-6786239 https://reactome.org/PathwayBrowser/#/R-DME-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Drosophila melanogaster 36005 R-DRE-6786239 https://reactome.org/PathwayBrowser/#/R-DRE-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Danio rerio 36005 R-GGA-6786239 https://reactome.org/PathwayBrowser/#/R-GGA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Gallus gallus 36005 R-HSA-6786239 https://reactome.org/PathwayBrowser/#/R-HSA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE TAS Homo sapiens 36005 R-HSA-9844415 https://reactome.org/PathwayBrowser/#/R-HSA-9844415 PRDM16 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 IEA Homo sapiens 36005 R-HSA-9844440 https://reactome.org/PathwayBrowser/#/R-HSA-9844440 PPARG binds EBF2-bound gene loci IEA Homo sapiens 36005 R-HSA-9844536 https://reactome.org/PathwayBrowser/#/R-HSA-9844536 PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 36005 R-HSA-9844549 https://reactome.org/PathwayBrowser/#/R-HSA-9844549 UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 36005 R-HSA-9844600 https://reactome.org/PathwayBrowser/#/R-HSA-9844600 CIDEA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 36005 R-HSA-9844822 https://reactome.org/PathwayBrowser/#/R-HSA-9844822 PPARGC1A gene expression is stimulated by EBF2 IEA Homo sapiens 36005 R-MMU-6786239 https://reactome.org/PathwayBrowser/#/R-MMU-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Mus musculus 36005 R-MMU-9844541 https://reactome.org/PathwayBrowser/#/R-MMU-9844541 Ppara gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 36005 R-MMU-9844554 https://reactome.org/PathwayBrowser/#/R-MMU-9844554 Ucp1 gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 36005 R-MMU-9844626 https://reactome.org/PathwayBrowser/#/R-MMU-9844626 Cidea gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 36005 R-MMU-9844655 https://reactome.org/PathwayBrowser/#/R-MMU-9844655 Dio2 gene expression is stimulated by Ebf2 and repressed by Znf423 and NuRD TAS Mus musculus 36005 R-MMU-9844700 https://reactome.org/PathwayBrowser/#/R-MMU-9844700 Pparg binds Ebf2-bound gene loci TAS Mus musculus 36005 R-MMU-9844775 https://reactome.org/PathwayBrowser/#/R-MMU-9844775 Prdm16 gene expression is stimulated by Ebf2 and Pparg and inhibited by Znf423 TAS Mus musculus 36005 R-MMU-9844841 https://reactome.org/PathwayBrowser/#/R-MMU-9844841 Ppargc1a gene expression is positively regulated by Ebf2 and Pparg TAS Mus musculus 36005 R-RNO-6786239 https://reactome.org/PathwayBrowser/#/R-RNO-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Rattus norvegicus 36005 R-SSC-6786239 https://reactome.org/PathwayBrowser/#/R-SSC-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Sus scrofa 36005 R-XTR-6786239 https://reactome.org/PathwayBrowser/#/R-XTR-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Xenopus tropicalis 36062 R-BTA-175983 https://reactome.org/PathwayBrowser/#/R-BTA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Bos taurus 36062 R-CFA-175983 https://reactome.org/PathwayBrowser/#/R-CFA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Canis familiaris 36062 R-DRE-175983 https://reactome.org/PathwayBrowser/#/R-DRE-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Danio rerio 36062 R-GGA-175983 https://reactome.org/PathwayBrowser/#/R-GGA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Gallus gallus 36062 R-HSA-175983 https://reactome.org/PathwayBrowser/#/R-HSA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ TAS Homo sapiens 36062 R-MMU-175983 https://reactome.org/PathwayBrowser/#/R-MMU-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Mus musculus 36062 R-RNO-175983 https://reactome.org/PathwayBrowser/#/R-RNO-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Rattus norvegicus 36062 R-SPO-175983 https://reactome.org/PathwayBrowser/#/R-SPO-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Schizosaccharomyces pombe 36062 R-SSC-175983 https://reactome.org/PathwayBrowser/#/R-SSC-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Sus scrofa 36062 R-XTR-175983 https://reactome.org/PathwayBrowser/#/R-XTR-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Xenopus tropicalis 36080 R-BTA-1022127 https://reactome.org/PathwayBrowser/#/R-BTA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Bos taurus 36080 R-BTA-1112666 https://reactome.org/PathwayBrowser/#/R-BTA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Bos taurus 36080 R-BTA-1236964 https://reactome.org/PathwayBrowser/#/R-BTA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Bos taurus 36080 R-BTA-1236965 https://reactome.org/PathwayBrowser/#/R-BTA-1236965 Export of peptide loaded MHC class I complex to PM IEA Bos taurus 36080 R-BTA-158744 https://reactome.org/PathwayBrowser/#/R-BTA-158744 crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin IEA Bos taurus 36080 R-BTA-158747 https://reactome.org/PathwayBrowser/#/R-BTA-158747 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) IEA Bos taurus 36080 R-BTA-158750 https://reactome.org/PathwayBrowser/#/R-BTA-158750 crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin IEA Bos taurus 36080 R-BTA-158756 https://reactome.org/PathwayBrowser/#/R-BTA-158756 crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen IEA Bos taurus 36080 R-BTA-158766 https://reactome.org/PathwayBrowser/#/R-BTA-158766 fibrin multimer, crosslinked -> fibrin digestion products (plasmin) IEA Bos taurus 36080 R-BTA-158781 https://reactome.org/PathwayBrowser/#/R-BTA-158781 crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) IEA Bos taurus 36080 R-BTA-158784 https://reactome.org/PathwayBrowser/#/R-BTA-158784 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen IEA Bos taurus 36080 R-BTA-158795 https://reactome.org/PathwayBrowser/#/R-BTA-158795 fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 IEA Bos taurus 36080 R-BTA-158800 https://reactome.org/PathwayBrowser/#/R-BTA-158800 fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 IEA Bos taurus 36080 R-BTA-166753 https://reactome.org/PathwayBrowser/#/R-BTA-166753 Conversion of C4 into C4a and C4b IEA Bos taurus 36080 R-BTA-166792 https://reactome.org/PathwayBrowser/#/R-BTA-166792 Conversion of C2 into C2a and C2b IEA Bos taurus 36080 R-BTA-173626 https://reactome.org/PathwayBrowser/#/R-BTA-173626 Activation of C1r IEA Bos taurus 36080 R-BTA-173631 https://reactome.org/PathwayBrowser/#/R-BTA-173631 Activation of C1s IEA Bos taurus 36080 R-BTA-1861621 https://reactome.org/PathwayBrowser/#/R-BTA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Bos taurus 36080 R-BTA-198955 https://reactome.org/PathwayBrowser/#/R-BTA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Bos taurus 36080 R-BTA-199518 https://reactome.org/PathwayBrowser/#/R-BTA-199518 C3d-complexed antigen binds to complement receptor IEA Bos taurus 36080 R-BTA-202165 https://reactome.org/PathwayBrowser/#/R-BTA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Bos taurus 36080 R-BTA-202168 https://reactome.org/PathwayBrowser/#/R-BTA-202168 Phosphorylation of ZAP-70 by Lck IEA Bos taurus 36080 R-BTA-202174 https://reactome.org/PathwayBrowser/#/R-BTA-202174 Activation of ZAP-70 IEA Bos taurus 36080 R-BTA-202214 https://reactome.org/PathwayBrowser/#/R-BTA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Bos taurus 36080 R-BTA-202216 https://reactome.org/PathwayBrowser/#/R-BTA-202216 Phosphorylation of SLP-76 IEA Bos taurus 36080 R-BTA-202233 https://reactome.org/PathwayBrowser/#/R-BTA-202233 Inactivation of Lck by Csk IEA Bos taurus 36080 R-BTA-202245 https://reactome.org/PathwayBrowser/#/R-BTA-202245 Phosphorylation of TBSMs in LAT IEA Bos taurus 36080 R-BTA-202248 https://reactome.org/PathwayBrowser/#/R-BTA-202248 Phosphorylation of PLC-gamma1 IEA Bos taurus 36080 R-BTA-202291 https://reactome.org/PathwayBrowser/#/R-BTA-202291 Activation of Lck IEA Bos taurus 36080 R-BTA-202307 https://reactome.org/PathwayBrowser/#/R-BTA-202307 Change of PKC theta conformation IEA Bos taurus 36080 R-BTA-202344 https://reactome.org/PathwayBrowser/#/R-BTA-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Bos taurus 36080 R-BTA-2029268 https://reactome.org/PathwayBrowser/#/R-BTA-2029268 Phosphorylation and activation of PLCG IEA Bos taurus 36080 R-BTA-2029270 https://reactome.org/PathwayBrowser/#/R-BTA-2029270 Recruitment of PLCgamma to membrane IEA Bos taurus 36080 R-BTA-2029271 https://reactome.org/PathwayBrowser/#/R-BTA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 36080 R-BTA-2029272 https://reactome.org/PathwayBrowser/#/R-BTA-2029272 Release of PLCG from FCGR IEA Bos taurus 36080 R-BTA-2029273 https://reactome.org/PathwayBrowser/#/R-BTA-2029273 PI3K binds to p-6Y-SYK IEA Bos taurus 36080 R-BTA-2029451 https://reactome.org/PathwayBrowser/#/R-BTA-2029451 Activation of RAC1 by VAV IEA Bos taurus 36080 R-BTA-2029452 https://reactome.org/PathwayBrowser/#/R-BTA-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Bos taurus 36080 R-BTA-2029453 https://reactome.org/PathwayBrowser/#/R-BTA-2029453 Phosphorylation of VAV IEA Bos taurus 36080 R-BTA-2029455 https://reactome.org/PathwayBrowser/#/R-BTA-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Bos taurus 36080 R-BTA-2029457 https://reactome.org/PathwayBrowser/#/R-BTA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Bos taurus 36080 R-BTA-2029458 https://reactome.org/PathwayBrowser/#/R-BTA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Bos taurus 36080 R-BTA-2029459 https://reactome.org/PathwayBrowser/#/R-BTA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Bos taurus 36080 R-BTA-2029467 https://reactome.org/PathwayBrowser/#/R-BTA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Bos taurus 36080 R-BTA-2029476 https://reactome.org/PathwayBrowser/#/R-BTA-2029476 Role of myosins in phagosome formation IEA Bos taurus 36080 R-BTA-2197697 https://reactome.org/PathwayBrowser/#/R-BTA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Bos taurus 36080 R-BTA-2213240 https://reactome.org/PathwayBrowser/#/R-BTA-2213240 Reduction of disulphide bonds in MHC II antigens IEA Bos taurus 36080 R-BTA-2529015 https://reactome.org/PathwayBrowser/#/R-BTA-2529015 Dephosphorylation of CK2-modified condensin I IEA Bos taurus 36080 R-BTA-2534076 https://reactome.org/PathwayBrowser/#/R-BTA-2534076 Unknown Nat N-acylates Gly in Gnat1 TAS Bos taurus 36080 R-BTA-3132759 https://reactome.org/PathwayBrowser/#/R-BTA-3132759 TCN1 binds RCbl IEA Bos taurus 36080 R-BTA-389758 https://reactome.org/PathwayBrowser/#/R-BTA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Bos taurus 36080 R-BTA-5690517 https://reactome.org/PathwayBrowser/#/R-BTA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Bos taurus 36080 R-BTA-5690701 https://reactome.org/PathwayBrowser/#/R-BTA-5690701 SHP1 binds p-CD22 IEA Bos taurus 36080 R-BTA-5690702 https://reactome.org/PathwayBrowser/#/R-BTA-5690702 LYN phosphorylates CD22 IEA Bos taurus 36080 R-BTA-5690740 https://reactome.org/PathwayBrowser/#/R-BTA-5690740 CD22 binds B-cell receptor IEA Bos taurus 36080 R-BTA-5691512 https://reactome.org/PathwayBrowser/#/R-BTA-5691512 APEH hydrolyses NAc-Ser-protein IEA Bos taurus 36080 R-BTA-72621 https://reactome.org/PathwayBrowser/#/R-BTA-72621 Ribosomal scanning IEA Bos taurus 36080 R-BTA-72697 https://reactome.org/PathwayBrowser/#/R-BTA-72697 Start codon recognition IEA Bos taurus 36080 R-BTA-8848658 https://reactome.org/PathwayBrowser/#/R-BTA-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Bos taurus 36080 R-BTA-8850594 https://reactome.org/PathwayBrowser/#/R-BTA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Bos taurus 36080 R-BTA-8852200 https://reactome.org/PathwayBrowser/#/R-BTA-8852200 Inactivation of LCK by PTPN22 IEA Bos taurus 36080 R-BTA-8852266 https://reactome.org/PathwayBrowser/#/R-BTA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Bos taurus 36080 R-BTA-8852481 https://reactome.org/PathwayBrowser/#/R-BTA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Bos taurus 36080 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 36080 R-BTA-8855381 https://reactome.org/PathwayBrowser/#/R-BTA-8855381 PTPN22 dephosphorylates ZAP70 IEA Bos taurus 36080 R-BTA-9021306 https://reactome.org/PathwayBrowser/#/R-BTA-9021306 C1-Inh binds and inactivates C1r, C1s IEA Bos taurus 36080 R-BTA-9606151 https://reactome.org/PathwayBrowser/#/R-BTA-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Bos taurus 36080 R-BTA-9691421 https://reactome.org/PathwayBrowser/#/R-BTA-9691421 BTK binds BTK inhibitors IEA Bos taurus 36080 R-BTA-9724745 https://reactome.org/PathwayBrowser/#/R-BTA-9724745 PLG(20-810) binds aprotinin IEA Bos taurus 36080 R-BTA-9724753 https://reactome.org/PathwayBrowser/#/R-BTA-9724753 PLG(20-810) binds anti-fibrinolytics IEA Bos taurus 36080 R-BTA-983427 https://reactome.org/PathwayBrowser/#/R-BTA-983427 Expression of peptide bound class I MHC on cell surface IEA Bos taurus 36080 R-BTA-983696 https://reactome.org/PathwayBrowser/#/R-BTA-983696 The Immunoglobulin of the BCR binds antigen IEA Bos taurus 36080 R-BTA-983700 https://reactome.org/PathwayBrowser/#/R-BTA-983700 SYK binds the activated BCR IEA Bos taurus 36080 R-BTA-983703 https://reactome.org/PathwayBrowser/#/R-BTA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Bos taurus 36080 R-BTA-983707 https://reactome.org/PathwayBrowser/#/R-BTA-983707 SYK autophosphorylates at the activated BCR IEA Bos taurus 36080 R-CEL-1022127 https://reactome.org/PathwayBrowser/#/R-CEL-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Caenorhabditis elegans 36080 R-CEL-158766 https://reactome.org/PathwayBrowser/#/R-CEL-158766 fibrin multimer, crosslinked -> fibrin digestion products (plasmin) IEA Caenorhabditis elegans 36080 R-CEL-2213240 https://reactome.org/PathwayBrowser/#/R-CEL-2213240 Reduction of disulphide bonds in MHC II antigens IEA Caenorhabditis elegans 36080 R-CEL-5690517 https://reactome.org/PathwayBrowser/#/R-CEL-5690517 PPT1 hydrolyses palmitoylated proteins IEA Caenorhabditis elegans 36080 R-CEL-5691512 https://reactome.org/PathwayBrowser/#/R-CEL-5691512 APEH hydrolyses NAc-Ser-protein IEA Caenorhabditis elegans 36080 R-CEL-72621 https://reactome.org/PathwayBrowser/#/R-CEL-72621 Ribosomal scanning IEA Caenorhabditis elegans 36080 R-CEL-72697 https://reactome.org/PathwayBrowser/#/R-CEL-72697 Start codon recognition IEA Caenorhabditis elegans 36080 R-CEL-8850594 https://reactome.org/PathwayBrowser/#/R-CEL-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Caenorhabditis elegans 36080 R-CFA-1022127 https://reactome.org/PathwayBrowser/#/R-CFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Canis familiaris 36080 R-CFA-1112666 https://reactome.org/PathwayBrowser/#/R-CFA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Canis familiaris 36080 R-CFA-1236964 https://reactome.org/PathwayBrowser/#/R-CFA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Canis familiaris 36080 R-CFA-1236965 https://reactome.org/PathwayBrowser/#/R-CFA-1236965 Export of peptide loaded MHC class I complex to PM IEA Canis familiaris 36080 R-CFA-158744 https://reactome.org/PathwayBrowser/#/R-CFA-158744 crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin IEA Canis familiaris 36080 R-CFA-158747 https://reactome.org/PathwayBrowser/#/R-CFA-158747 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) IEA Canis familiaris 36080 R-CFA-158750 https://reactome.org/PathwayBrowser/#/R-CFA-158750 crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin IEA Canis familiaris 36080 R-CFA-158756 https://reactome.org/PathwayBrowser/#/R-CFA-158756 crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen IEA Canis familiaris 36080 R-CFA-158766 https://reactome.org/PathwayBrowser/#/R-CFA-158766 fibrin multimer, crosslinked -> fibrin digestion products (plasmin) IEA Canis familiaris 36080 R-CFA-158781 https://reactome.org/PathwayBrowser/#/R-CFA-158781 crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) IEA Canis familiaris 36080 R-CFA-158784 https://reactome.org/PathwayBrowser/#/R-CFA-158784 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen IEA Canis familiaris 36080 R-CFA-158795 https://reactome.org/PathwayBrowser/#/R-CFA-158795 fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 IEA Canis familiaris 36080 R-CFA-158800 https://reactome.org/PathwayBrowser/#/R-CFA-158800 fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 IEA Canis familiaris 36080 R-CFA-166753 https://reactome.org/PathwayBrowser/#/R-CFA-166753 Conversion of C4 into C4a and C4b IEA Canis familiaris 36080 R-CFA-166792 https://reactome.org/PathwayBrowser/#/R-CFA-166792 Conversion of C2 into C2a and C2b IEA Canis familiaris 36080 R-CFA-173626 https://reactome.org/PathwayBrowser/#/R-CFA-173626 Activation of C1r IEA Canis familiaris 36080 R-CFA-173631 https://reactome.org/PathwayBrowser/#/R-CFA-173631 Activation of C1s IEA Canis familiaris 36080 R-CFA-1861621 https://reactome.org/PathwayBrowser/#/R-CFA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Canis familiaris 36080 R-CFA-198955 https://reactome.org/PathwayBrowser/#/R-CFA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Canis familiaris 36080 R-CFA-199518 https://reactome.org/PathwayBrowser/#/R-CFA-199518 C3d-complexed antigen binds to complement receptor IEA Canis familiaris 36080 R-CFA-202165 https://reactome.org/PathwayBrowser/#/R-CFA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Canis familiaris 36080 R-CFA-202168 https://reactome.org/PathwayBrowser/#/R-CFA-202168 Phosphorylation of ZAP-70 by Lck IEA Canis familiaris 36080 R-CFA-202174 https://reactome.org/PathwayBrowser/#/R-CFA-202174 Activation of ZAP-70 IEA Canis familiaris 36080 R-CFA-202214 https://reactome.org/PathwayBrowser/#/R-CFA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Canis familiaris 36080 R-CFA-202216 https://reactome.org/PathwayBrowser/#/R-CFA-202216 Phosphorylation of SLP-76 IEA Canis familiaris 36080 R-CFA-202233 https://reactome.org/PathwayBrowser/#/R-CFA-202233 Inactivation of Lck by Csk IEA Canis familiaris 36080 R-CFA-202245 https://reactome.org/PathwayBrowser/#/R-CFA-202245 Phosphorylation of TBSMs in LAT IEA Canis familiaris 36080 R-CFA-202248 https://reactome.org/PathwayBrowser/#/R-CFA-202248 Phosphorylation of PLC-gamma1 IEA Canis familiaris 36080 R-CFA-202291 https://reactome.org/PathwayBrowser/#/R-CFA-202291 Activation of Lck IEA Canis familiaris 36080 R-CFA-202307 https://reactome.org/PathwayBrowser/#/R-CFA-202307 Change of PKC theta conformation IEA Canis familiaris 36080 R-CFA-202344 https://reactome.org/PathwayBrowser/#/R-CFA-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Canis familiaris 36080 R-CFA-2029268 https://reactome.org/PathwayBrowser/#/R-CFA-2029268 Phosphorylation and activation of PLCG IEA Canis familiaris 36080 R-CFA-2029270 https://reactome.org/PathwayBrowser/#/R-CFA-2029270 Recruitment of PLCgamma to membrane IEA Canis familiaris 36080 R-CFA-2029271 https://reactome.org/PathwayBrowser/#/R-CFA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 36080 R-CFA-2029272 https://reactome.org/PathwayBrowser/#/R-CFA-2029272 Release of PLCG from FCGR IEA Canis familiaris 36080 R-CFA-2029273 https://reactome.org/PathwayBrowser/#/R-CFA-2029273 PI3K binds to p-6Y-SYK IEA Canis familiaris 36080 R-CFA-2029451 https://reactome.org/PathwayBrowser/#/R-CFA-2029451 Activation of RAC1 by VAV IEA Canis familiaris 36080 R-CFA-2029452 https://reactome.org/PathwayBrowser/#/R-CFA-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Canis familiaris 36080 R-CFA-2029453 https://reactome.org/PathwayBrowser/#/R-CFA-2029453 Phosphorylation of VAV IEA Canis familiaris 36080 R-CFA-2029455 https://reactome.org/PathwayBrowser/#/R-CFA-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Canis familiaris 36080 R-CFA-2029457 https://reactome.org/PathwayBrowser/#/R-CFA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Canis familiaris 36080 R-CFA-2029458 https://reactome.org/PathwayBrowser/#/R-CFA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Canis familiaris 36080 R-CFA-2029459 https://reactome.org/PathwayBrowser/#/R-CFA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Canis familiaris 36080 R-CFA-2029467 https://reactome.org/PathwayBrowser/#/R-CFA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Canis familiaris 36080 R-CFA-2029476 https://reactome.org/PathwayBrowser/#/R-CFA-2029476 Role of myosins in phagosome formation IEA Canis familiaris 36080 R-CFA-2197697 https://reactome.org/PathwayBrowser/#/R-CFA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Canis familiaris 36080 R-CFA-2213240 https://reactome.org/PathwayBrowser/#/R-CFA-2213240 Reduction of disulphide bonds in MHC II antigens IEA Canis familiaris 36080 R-CFA-2529015 https://reactome.org/PathwayBrowser/#/R-CFA-2529015 Dephosphorylation of CK2-modified condensin I IEA Canis familiaris 36080 R-CFA-3132759 https://reactome.org/PathwayBrowser/#/R-CFA-3132759 TCN1 binds RCbl IEA Canis familiaris 36080 R-CFA-389758 https://reactome.org/PathwayBrowser/#/R-CFA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Canis familiaris 36080 R-CFA-5690517 https://reactome.org/PathwayBrowser/#/R-CFA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Canis familiaris 36080 R-CFA-5690701 https://reactome.org/PathwayBrowser/#/R-CFA-5690701 SHP1 binds p-CD22 IEA Canis familiaris 36080 R-CFA-5690702 https://reactome.org/PathwayBrowser/#/R-CFA-5690702 LYN phosphorylates CD22 IEA Canis familiaris 36080 R-CFA-5690740 https://reactome.org/PathwayBrowser/#/R-CFA-5690740 CD22 binds B-cell receptor IEA Canis familiaris 36080 R-CFA-5691512 https://reactome.org/PathwayBrowser/#/R-CFA-5691512 APEH hydrolyses NAc-Ser-protein IEA Canis familiaris 36080 R-CFA-72619 https://reactome.org/PathwayBrowser/#/R-CFA-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Canis familiaris 36080 R-CFA-72621 https://reactome.org/PathwayBrowser/#/R-CFA-72621 Ribosomal scanning IEA Canis familiaris 36080 R-CFA-72647 https://reactome.org/PathwayBrowser/#/R-CFA-72647 Cap-bound mRNA is activated by helicases IEA Canis familiaris 36080 R-CFA-72697 https://reactome.org/PathwayBrowser/#/R-CFA-72697 Start codon recognition IEA Canis familiaris 36080 R-CFA-8848658 https://reactome.org/PathwayBrowser/#/R-CFA-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Canis familiaris 36080 R-CFA-8850594 https://reactome.org/PathwayBrowser/#/R-CFA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Canis familiaris 36080 R-CFA-8852200 https://reactome.org/PathwayBrowser/#/R-CFA-8852200 Inactivation of LCK by PTPN22 IEA Canis familiaris 36080 R-CFA-8852266 https://reactome.org/PathwayBrowser/#/R-CFA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Canis familiaris 36080 R-CFA-8852481 https://reactome.org/PathwayBrowser/#/R-CFA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Canis familiaris 36080 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 36080 R-CFA-8855381 https://reactome.org/PathwayBrowser/#/R-CFA-8855381 PTPN22 dephosphorylates ZAP70 IEA Canis familiaris 36080 R-CFA-9021306 https://reactome.org/PathwayBrowser/#/R-CFA-9021306 C1-Inh binds and inactivates C1r, C1s IEA Canis familiaris 36080 R-CFA-9606151 https://reactome.org/PathwayBrowser/#/R-CFA-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Canis familiaris 36080 R-CFA-9691421 https://reactome.org/PathwayBrowser/#/R-CFA-9691421 BTK binds BTK inhibitors IEA Canis familiaris 36080 R-CFA-9724745 https://reactome.org/PathwayBrowser/#/R-CFA-9724745 PLG(20-810) binds aprotinin IEA Canis familiaris 36080 R-CFA-9724753 https://reactome.org/PathwayBrowser/#/R-CFA-9724753 PLG(20-810) binds anti-fibrinolytics IEA Canis familiaris 36080 R-CFA-983427 https://reactome.org/PathwayBrowser/#/R-CFA-983427 Expression of peptide bound class I MHC on cell surface IEA Canis familiaris 36080 R-CFA-983696 https://reactome.org/PathwayBrowser/#/R-CFA-983696 The Immunoglobulin of the BCR binds antigen IEA Canis familiaris 36080 R-CFA-983700 https://reactome.org/PathwayBrowser/#/R-CFA-983700 SYK binds the activated BCR IEA Canis familiaris 36080 R-CFA-983703 https://reactome.org/PathwayBrowser/#/R-CFA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Canis familiaris 36080 R-CFA-983707 https://reactome.org/PathwayBrowser/#/R-CFA-983707 SYK autophosphorylates at the activated BCR IEA Canis familiaris 36080 R-DDI-1022127 https://reactome.org/PathwayBrowser/#/R-DDI-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Dictyostelium discoideum 36080 R-DDI-2529015 https://reactome.org/PathwayBrowser/#/R-DDI-2529015 Dephosphorylation of CK2-modified condensin I IEA Dictyostelium discoideum 36080 R-DDI-5690517 https://reactome.org/PathwayBrowser/#/R-DDI-5690517 PPT1 hydrolyses palmitoylated proteins IEA Dictyostelium discoideum 36080 R-DDI-5691512 https://reactome.org/PathwayBrowser/#/R-DDI-5691512 APEH hydrolyses NAc-Ser-protein IEA Dictyostelium discoideum 36080 R-DDI-72621 https://reactome.org/PathwayBrowser/#/R-DDI-72621 Ribosomal scanning IEA Dictyostelium discoideum 36080 R-DDI-72697 https://reactome.org/PathwayBrowser/#/R-DDI-72697 Start codon recognition IEA Dictyostelium discoideum 36080 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 36080 R-DME-1022127 https://reactome.org/PathwayBrowser/#/R-DME-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Drosophila melanogaster 36080 R-DME-2213240 https://reactome.org/PathwayBrowser/#/R-DME-2213240 Reduction of disulphide bonds in MHC II antigens IEA Drosophila melanogaster 36080 R-DME-2529015 https://reactome.org/PathwayBrowser/#/R-DME-2529015 Dephosphorylation of CK2-modified condensin I IEA Drosophila melanogaster 36080 R-DME-3132759 https://reactome.org/PathwayBrowser/#/R-DME-3132759 TCN1 binds RCbl IEA Drosophila melanogaster 36080 R-DME-5690517 https://reactome.org/PathwayBrowser/#/R-DME-5690517 PPT1 hydrolyses palmitoylated proteins IEA Drosophila melanogaster 36080 R-DME-72621 https://reactome.org/PathwayBrowser/#/R-DME-72621 Ribosomal scanning IEA Drosophila melanogaster 36080 R-DME-72697 https://reactome.org/PathwayBrowser/#/R-DME-72697 Start codon recognition IEA Drosophila melanogaster 36080 R-DME-8850594 https://reactome.org/PathwayBrowser/#/R-DME-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Drosophila melanogaster 36080 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 36080 R-DRE-1022127 https://reactome.org/PathwayBrowser/#/R-DRE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Danio rerio 36080 R-DRE-1236964 https://reactome.org/PathwayBrowser/#/R-DRE-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Danio rerio 36080 R-DRE-1236965 https://reactome.org/PathwayBrowser/#/R-DRE-1236965 Export of peptide loaded MHC class I complex to PM IEA Danio rerio 36080 R-DRE-2213240 https://reactome.org/PathwayBrowser/#/R-DRE-2213240 Reduction of disulphide bonds in MHC II antigens IEA Danio rerio 36080 R-DRE-5690517 https://reactome.org/PathwayBrowser/#/R-DRE-5690517 PPT1 hydrolyses palmitoylated proteins IEA Danio rerio 36080 R-DRE-72621 https://reactome.org/PathwayBrowser/#/R-DRE-72621 Ribosomal scanning IEA Danio rerio 36080 R-DRE-72697 https://reactome.org/PathwayBrowser/#/R-DRE-72697 Start codon recognition IEA Danio rerio 36080 R-DRE-8848658 https://reactome.org/PathwayBrowser/#/R-DRE-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Danio rerio 36080 R-DRE-8850594 https://reactome.org/PathwayBrowser/#/R-DRE-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Danio rerio 36080 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 36080 R-DRE-983427 https://reactome.org/PathwayBrowser/#/R-DRE-983427 Expression of peptide bound class I MHC on cell surface IEA Danio rerio 36080 R-GGA-1022127 https://reactome.org/PathwayBrowser/#/R-GGA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Gallus gallus 36080 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus 36080 R-GGA-1236964 https://reactome.org/PathwayBrowser/#/R-GGA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Gallus gallus 36080 R-GGA-1236965 https://reactome.org/PathwayBrowser/#/R-GGA-1236965 Export of peptide loaded MHC class I complex to PM IEA Gallus gallus 36080 R-GGA-140851 https://reactome.org/PathwayBrowser/#/R-GGA-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Gallus gallus 36080 R-GGA-158744 https://reactome.org/PathwayBrowser/#/R-GGA-158744 crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin IEA Gallus gallus 36080 R-GGA-158747 https://reactome.org/PathwayBrowser/#/R-GGA-158747 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) IEA Gallus gallus 36080 R-GGA-158750 https://reactome.org/PathwayBrowser/#/R-GGA-158750 crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin IEA Gallus gallus 36080 R-GGA-158756 https://reactome.org/PathwayBrowser/#/R-GGA-158756 crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen IEA Gallus gallus 36080 R-GGA-158766 https://reactome.org/PathwayBrowser/#/R-GGA-158766 fibrin multimer, crosslinked -> fibrin digestion products (plasmin) IEA Gallus gallus 36080 R-GGA-158781 https://reactome.org/PathwayBrowser/#/R-GGA-158781 crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) IEA Gallus gallus 36080 R-GGA-158784 https://reactome.org/PathwayBrowser/#/R-GGA-158784 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen IEA Gallus gallus 36080 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus 36080 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus 36080 R-GGA-173626 https://reactome.org/PathwayBrowser/#/R-GGA-173626 Activation of C1r IEA Gallus gallus 36080 R-GGA-173631 https://reactome.org/PathwayBrowser/#/R-GGA-173631 Activation of C1s IEA Gallus gallus 36080 R-GGA-1861621 https://reactome.org/PathwayBrowser/#/R-GGA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Gallus gallus 36080 R-GGA-198955 https://reactome.org/PathwayBrowser/#/R-GGA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Gallus gallus 36080 R-GGA-199161 https://reactome.org/PathwayBrowser/#/R-GGA-199161 Fc gamma receptors interact with antigen-bound IgG IEA Gallus gallus 36080 R-GGA-202165 https://reactome.org/PathwayBrowser/#/R-GGA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Gallus gallus 36080 R-GGA-202168 https://reactome.org/PathwayBrowser/#/R-GGA-202168 Phosphorylation of ZAP-70 by Lck IEA Gallus gallus 36080 R-GGA-202174 https://reactome.org/PathwayBrowser/#/R-GGA-202174 Activation of ZAP-70 IEA Gallus gallus 36080 R-GGA-202214 https://reactome.org/PathwayBrowser/#/R-GGA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Gallus gallus 36080 R-GGA-202233 https://reactome.org/PathwayBrowser/#/R-GGA-202233 Inactivation of Lck by Csk IEA Gallus gallus 36080 R-GGA-202248 https://reactome.org/PathwayBrowser/#/R-GGA-202248 Phosphorylation of PLC-gamma1 IEA Gallus gallus 36080 R-GGA-202291 https://reactome.org/PathwayBrowser/#/R-GGA-202291 Activation of Lck IEA Gallus gallus 36080 R-GGA-202344 https://reactome.org/PathwayBrowser/#/R-GGA-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Gallus gallus 36080 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus 36080 R-GGA-2029270 https://reactome.org/PathwayBrowser/#/R-GGA-2029270 Recruitment of PLCgamma to membrane IEA Gallus gallus 36080 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 36080 R-GGA-2029272 https://reactome.org/PathwayBrowser/#/R-GGA-2029272 Release of PLCG from FCGR IEA Gallus gallus 36080 R-GGA-2029273 https://reactome.org/PathwayBrowser/#/R-GGA-2029273 PI3K binds to p-6Y-SYK IEA Gallus gallus 36080 R-GGA-2029451 https://reactome.org/PathwayBrowser/#/R-GGA-2029451 Activation of RAC1 by VAV IEA Gallus gallus 36080 R-GGA-2029452 https://reactome.org/PathwayBrowser/#/R-GGA-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Gallus gallus 36080 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus 36080 R-GGA-2029455 https://reactome.org/PathwayBrowser/#/R-GGA-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Gallus gallus 36080 R-GGA-2029457 https://reactome.org/PathwayBrowser/#/R-GGA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Gallus gallus 36080 R-GGA-2029458 https://reactome.org/PathwayBrowser/#/R-GGA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Gallus gallus 36080 R-GGA-2029459 https://reactome.org/PathwayBrowser/#/R-GGA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Gallus gallus 36080 R-GGA-2029467 https://reactome.org/PathwayBrowser/#/R-GGA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Gallus gallus 36080 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus 36080 R-GGA-2132064 https://reactome.org/PathwayBrowser/#/R-GGA-2132064 Antigen bound antibody interacts with C1complement complex TAS Gallus gallus 36080 R-GGA-2132065 https://reactome.org/PathwayBrowser/#/R-GGA-2132065 C1r activates C1s component within C1 complement complex IEA Gallus gallus 36080 R-GGA-2132122 https://reactome.org/PathwayBrowser/#/R-GGA-2132122 Activation of C1r within the C1complement complex IEA Gallus gallus 36080 R-GGA-2132222 https://reactome.org/PathwayBrowser/#/R-GGA-2132222 Cleavage of factor B to form classical C3 convertase TAS Gallus gallus 36080 R-GGA-2132233 https://reactome.org/PathwayBrowser/#/R-GGA-2132233 Proteolytic cleavage of complement factor C4 TAS Gallus gallus 36080 R-GGA-2197697 https://reactome.org/PathwayBrowser/#/R-GGA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Gallus gallus 36080 R-GGA-2213240 https://reactome.org/PathwayBrowser/#/R-GGA-2213240 Reduction of disulphide bonds in MHC II antigens IEA Gallus gallus 36080 R-GGA-2529015 https://reactome.org/PathwayBrowser/#/R-GGA-2529015 Dephosphorylation of CK2-modified condensin I IEA Gallus gallus 36080 R-GGA-389758 https://reactome.org/PathwayBrowser/#/R-GGA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Gallus gallus 36080 R-GGA-5690517 https://reactome.org/PathwayBrowser/#/R-GGA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Gallus gallus 36080 R-GGA-5691512 https://reactome.org/PathwayBrowser/#/R-GGA-5691512 APEH hydrolyses NAc-Ser-protein IEA Gallus gallus 36080 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus 36080 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus 36080 R-GGA-8850594 https://reactome.org/PathwayBrowser/#/R-GGA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Gallus gallus 36080 R-GGA-8852200 https://reactome.org/PathwayBrowser/#/R-GGA-8852200 Inactivation of LCK by PTPN22 IEA Gallus gallus 36080 R-GGA-8852266 https://reactome.org/PathwayBrowser/#/R-GGA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Gallus gallus 36080 R-GGA-8852481 https://reactome.org/PathwayBrowser/#/R-GGA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Gallus gallus 36080 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 36080 R-GGA-8855381 https://reactome.org/PathwayBrowser/#/R-GGA-8855381 PTPN22 dephosphorylates ZAP70 IEA Gallus gallus 36080 R-GGA-9021306 https://reactome.org/PathwayBrowser/#/R-GGA-9021306 C1-Inh binds and inactivates C1r, C1s IEA Gallus gallus 36080 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus 36080 R-GGA-9724745 https://reactome.org/PathwayBrowser/#/R-GGA-9724745 PLG(20-810) binds aprotinin IEA Gallus gallus 36080 R-GGA-9724753 https://reactome.org/PathwayBrowser/#/R-GGA-9724753 PLG(20-810) binds anti-fibrinolytics IEA Gallus gallus 36080 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus 36080 R-GGA-983696 https://reactome.org/PathwayBrowser/#/R-GGA-983696 The Immunoglobulin of the BCR binds antigen IEA Gallus gallus 36080 R-GGA-983700 https://reactome.org/PathwayBrowser/#/R-GGA-983700 SYK binds the activated BCR IEA Gallus gallus 36080 R-GGA-983703 https://reactome.org/PathwayBrowser/#/R-GGA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Gallus gallus 36080 R-GGA-983707 https://reactome.org/PathwayBrowser/#/R-GGA-983707 SYK autophosphorylates at the activated BCR IEA Gallus gallus 36080 R-HSA-1017228 https://reactome.org/PathwayBrowser/#/R-HSA-1017228 Glycoproteins with lesser folding defects get transported back to the ER and the CNX/CRT complex TAS Homo sapiens 36080 R-HSA-1022127 https://reactome.org/PathwayBrowser/#/R-HSA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol TAS Homo sapiens 36080 R-HSA-1112666 https://reactome.org/PathwayBrowser/#/R-HSA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate TAS Homo sapiens 36080 R-HSA-111930 https://reactome.org/PathwayBrowser/#/R-HSA-111930 Adenylate cyclase produces cAMP TAS Homo sapiens 36080 R-HSA-114563 https://reactome.org/PathwayBrowser/#/R-HSA-114563 Collagen type I binds integrin alpha1beta1, alpha2beta1, alpha10beta1 IEA Homo sapiens 36080 R-HSA-114577 https://reactome.org/PathwayBrowser/#/R-HSA-114577 Binding of GPVI:Fc Epsilon R1 gamma receptor complex with collagen TAS Homo sapiens 36080 R-HSA-114600 https://reactome.org/PathwayBrowser/#/R-HSA-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma TAS Homo sapiens 36080 R-HSA-114670 https://reactome.org/PathwayBrowser/#/R-HSA-114670 GPIb-IX-V binds to vWF:Collagen complex TAS Homo sapiens 36080 R-HSA-114671 https://reactome.org/PathwayBrowser/#/R-HSA-114671 vWF binds to collagen TAS Homo sapiens 36080 R-HSA-1236938 https://reactome.org/PathwayBrowser/#/R-HSA-1236938 Partial proteolysis of antigen in phagolysosomes TAS Homo sapiens 36080 R-HSA-1236964 https://reactome.org/PathwayBrowser/#/R-HSA-1236964 Translocation of peptide bound MHC class I complex to cell surface TAS Homo sapiens 36080 R-HSA-1236965 https://reactome.org/PathwayBrowser/#/R-HSA-1236965 Export of peptide loaded MHC class I complex to PM TAS Homo sapiens 36080 R-HSA-1296421 https://reactome.org/PathwayBrowser/#/R-HSA-1296421 NLRP3 oligomerizes via NACHT domains TAS Homo sapiens 36080 R-HSA-139842 https://reactome.org/PathwayBrowser/#/R-HSA-139842 Binding of Syk tyrosine kinase TAS Homo sapiens 36080 R-HSA-139908 https://reactome.org/PathwayBrowser/#/R-HSA-139908 Phosphorylation of DLC2 by MAPK8 TAS Homo sapiens 36080 R-HSA-139918 https://reactome.org/PathwayBrowser/#/R-HSA-139918 Phosphorylation of BIM by JNK TAS Homo sapiens 36080 R-HSA-140851 https://reactome.org/PathwayBrowser/#/R-HSA-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ TAS Homo sapiens 36080 R-HSA-141671 https://reactome.org/PathwayBrowser/#/R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex IEA Homo sapiens 36080 R-HSA-1454757 https://reactome.org/PathwayBrowser/#/R-HSA-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 TAS Homo sapiens 36080 R-HSA-1454822 https://reactome.org/PathwayBrowser/#/R-HSA-1454822 Collagen type I degradation by MMP1,2,8,13, PRSS2 TAS Homo sapiens 36080 R-HSA-1458433 https://reactome.org/PathwayBrowser/#/R-HSA-1458433 Collagen type I degradation by MMP14 IEA Homo sapiens 36080 R-HSA-1474196 https://reactome.org/PathwayBrowser/#/R-HSA-1474196 Collagen type II degradation by MMP14 IEA Homo sapiens 36080 R-HSA-1474197 https://reactome.org/PathwayBrowser/#/R-HSA-1474197 Collagen type II degradation by MMP1,3,8,13,PRSS2 TAS Homo sapiens 36080 R-HSA-1474210 https://reactome.org/PathwayBrowser/#/R-HSA-1474210 Collagen type III degradation by MMP14 TAS Homo sapiens 36080 R-HSA-1474213 https://reactome.org/PathwayBrowser/#/R-HSA-1474213 Collagen type III degradation by MMP1,8,9,13 TAS Homo sapiens 36080 R-HSA-1474266 https://reactome.org/PathwayBrowser/#/R-HSA-1474266 Formation of collagen fibrils TAS Homo sapiens 36080 R-HSA-1564112 https://reactome.org/PathwayBrowser/#/R-HSA-1564112 Collagen type VI degradation by MMP2,9,11 TAS Homo sapiens 36080 R-HSA-1564120 https://reactome.org/PathwayBrowser/#/R-HSA-1564120 Collagen type VII degradation by MMP1,2,3 TAS Homo sapiens 36080 R-HSA-1564142 https://reactome.org/PathwayBrowser/#/R-HSA-1564142 Collagen type IV degradation by MMP2,3,4,9,10,12 TAS Homo sapiens 36080 R-HSA-1564143 https://reactome.org/PathwayBrowser/#/R-HSA-1564143 Collagen type X degradation by MMP1,2 IEA Homo sapiens 36080 R-HSA-1564164 https://reactome.org/PathwayBrowser/#/R-HSA-1564164 Collagen type V degradation by MMP2,9,10 TAS Homo sapiens 36080 R-HSA-1564169 https://reactome.org/PathwayBrowser/#/R-HSA-1564169 Collagen type VIII degradation by MMP1 TAS Homo sapiens 36080 R-HSA-1564179 https://reactome.org/PathwayBrowser/#/R-HSA-1564179 Collagen type XI degradation by MMP1,2,3,9 IEA Homo sapiens 36080 R-HSA-1566962 https://reactome.org/PathwayBrowser/#/R-HSA-1566962 Elastin degradation by elastin-degrading extracellular proteinases TAS Homo sapiens 36080 R-HSA-1566981 https://reactome.org/PathwayBrowser/#/R-HSA-1566981 Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS TAS Homo sapiens 36080 R-HSA-156832 https://reactome.org/PathwayBrowser/#/R-HSA-156832 INF-gamma induced phosphorylation of L13a TAS Homo sapiens 36080 R-HSA-158744 https://reactome.org/PathwayBrowser/#/R-HSA-158744 crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin TAS Homo sapiens 36080 R-HSA-158747 https://reactome.org/PathwayBrowser/#/R-HSA-158747 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) TAS Homo sapiens 36080 R-HSA-158750 https://reactome.org/PathwayBrowser/#/R-HSA-158750 crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin TAS Homo sapiens 36080 R-HSA-158756 https://reactome.org/PathwayBrowser/#/R-HSA-158756 crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen TAS Homo sapiens 36080 R-HSA-158766 https://reactome.org/PathwayBrowser/#/R-HSA-158766 fibrin multimer, crosslinked -> fibrin digestion products (plasmin) TAS Homo sapiens 36080 R-HSA-158781 https://reactome.org/PathwayBrowser/#/R-HSA-158781 crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) TAS Homo sapiens 36080 R-HSA-158784 https://reactome.org/PathwayBrowser/#/R-HSA-158784 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen TAS Homo sapiens 36080 R-HSA-158795 https://reactome.org/PathwayBrowser/#/R-HSA-158795 fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 TAS Homo sapiens 36080 R-HSA-158800 https://reactome.org/PathwayBrowser/#/R-HSA-158800 fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 TAS Homo sapiens 36080 R-HSA-1592387 https://reactome.org/PathwayBrowser/#/R-HSA-1592387 Fibulin binds elastic fibres TAS Homo sapiens 36080 R-HSA-1630304 https://reactome.org/PathwayBrowser/#/R-HSA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate TAS Homo sapiens 36080 R-HSA-1638803 https://reactome.org/PathwayBrowser/#/R-HSA-1638803 Phosphorylation of cohesin by PLK1 at centromeres TAS Homo sapiens 36080 R-HSA-1638821 https://reactome.org/PathwayBrowser/#/R-HSA-1638821 PP2A-B56 dephosphorylates centromeric cohesin TAS Homo sapiens 36080 R-HSA-164500 https://reactome.org/PathwayBrowser/#/R-HSA-164500 Conformational changes in gp120 exposes gp41 TAS Homo sapiens 36080 R-HSA-164507 https://reactome.org/PathwayBrowser/#/R-HSA-164507 CD4:gp120 binds to chemokine co-receptor CCR5/CXCR4 TAS Homo sapiens 36080 R-HSA-164508 https://reactome.org/PathwayBrowser/#/R-HSA-164508 N and C terminal heptad repeat helices of gp41 form six-helix bundle TAS Homo sapiens 36080 R-HSA-164509 https://reactome.org/PathwayBrowser/#/R-HSA-164509 Binding of gp120 of ENV oligomer to the host CD4 TAS Homo sapiens 36080 R-HSA-164510 https://reactome.org/PathwayBrowser/#/R-HSA-164510 Conformational change in gp120 of Env oligomer TAS Homo sapiens 36080 R-HSA-164515 https://reactome.org/PathwayBrowser/#/R-HSA-164515 Fusogenic activation of gp41 TAS Homo sapiens 36080 R-HSA-164521 https://reactome.org/PathwayBrowser/#/R-HSA-164521 Insertion of gp41 fusion peptide into the target membrane TAS Homo sapiens 36080 R-HSA-164524 https://reactome.org/PathwayBrowser/#/R-HSA-164524 Fusion of viral membrane with host cell membrane TAS Homo sapiens 36080 R-HSA-164967 https://reactome.org/PathwayBrowser/#/R-HSA-164967 Unknown carnitine exporter transports CAR from the cytosol to the extracellular space TAS Homo sapiens 36080 R-HSA-165028 https://reactome.org/PathwayBrowser/#/R-HSA-165028 Release of the HIV mRNA and Crm1 from Rev in the cytoplasm TAS Homo sapiens 36080 R-HSA-165033 https://reactome.org/PathwayBrowser/#/R-HSA-165033 Multimerization of Rev TAS Homo sapiens 36080 R-HSA-165034 https://reactome.org/PathwayBrowser/#/R-HSA-165034 Rev multimer-bound HIV mRNA:CRM1 complex associates with Ran:GTP TAS Homo sapiens 36080 R-HSA-165043 https://reactome.org/PathwayBrowser/#/R-HSA-165043 Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC TAS Homo sapiens 36080 R-HSA-165047 https://reactome.org/PathwayBrowser/#/R-HSA-165047 Translocation of nuclear RNA transport complex to cytoplasm TAS Homo sapiens 36080 R-HSA-165055 https://reactome.org/PathwayBrowser/#/R-HSA-165055 Hydrolysis of Ran:GTP to Ran:GDP TAS Homo sapiens 36080 R-HSA-166041 https://reactome.org/PathwayBrowser/#/R-HSA-166041 Transfer of LPS onto TLR4 TAS Homo sapiens 36080 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens 36080 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens 36080 R-HSA-166817 https://reactome.org/PathwayBrowser/#/R-HSA-166817 Cleavage of C3 by C3 convertases TAS Homo sapiens 36080 R-HSA-1678660 https://reactome.org/PathwayBrowser/#/R-HSA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) TAS Homo sapiens 36080 R-HSA-168184 https://reactome.org/PathwayBrowser/#/R-HSA-168184 Activated TAK1 mediates phosphorylation of the IKK Complex TAS Homo sapiens 36080 R-HSA-168915 https://reactome.org/PathwayBrowser/#/R-HSA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex TAS Homo sapiens 36080 R-HSA-168951 https://reactome.org/PathwayBrowser/#/R-HSA-168951 TLR1:TLR2 is recruited to ligand:CD14 TAS Homo sapiens 36080 R-HSA-173111 https://reactome.org/PathwayBrowser/#/R-HSA-173111 Disassembly of viral capsid TAS Homo sapiens 36080 R-HSA-173626 https://reactome.org/PathwayBrowser/#/R-HSA-173626 Activation of C1r TAS Homo sapiens 36080 R-HSA-173631 https://reactome.org/PathwayBrowser/#/R-HSA-173631 Activation of C1s TAS Homo sapiens 36080 R-HSA-173642 https://reactome.org/PathwayBrowser/#/R-HSA-173642 Disintegration of matrix layer TAS Homo sapiens 36080 R-HSA-173680 https://reactome.org/PathwayBrowser/#/R-HSA-173680 Activation of C5 TAS Homo sapiens 36080 R-HSA-173754 https://reactome.org/PathwayBrowser/#/R-HSA-173754 Properdin stabilizes C3b:Bb bound to cell surfaces TAS Homo sapiens 36080 R-HSA-174551 https://reactome.org/PathwayBrowser/#/R-HSA-174551 Formation of alternative pathway C5 convertase TAS Homo sapiens 36080 R-HSA-175976 https://reactome.org/PathwayBrowser/#/R-HSA-175976 TMT transfers CH3 from AdoMet to BME TAS Homo sapiens 36080 R-HSA-176298 https://reactome.org/PathwayBrowser/#/R-HSA-176298 Activation of claspin TAS Homo sapiens 36080 R-HSA-176318 https://reactome.org/PathwayBrowser/#/R-HSA-176318 Loading of claspin onto DNA during replication origin firing TAS Homo sapiens 36080 R-HSA-177160 https://reactome.org/PathwayBrowser/#/R-HSA-177160 phenylacetyl-CoA + glutamine => phenylacetyl glutamine + Coenzyme A TAS Homo sapiens 36080 R-HSA-177690 https://reactome.org/PathwayBrowser/#/R-HSA-177690 Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex TAS Homo sapiens 36080 R-HSA-177692 https://reactome.org/PathwayBrowser/#/R-HSA-177692 Activation of recruited TAK1 within the activated TLR3 complex TAS Homo sapiens 36080 R-HSA-1793176 https://reactome.org/PathwayBrowser/#/R-HSA-1793176 DS is cleaved from its proteoglycan TAS Homo sapiens 36080 R-HSA-1793217 https://reactome.org/PathwayBrowser/#/R-HSA-1793217 Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase TAS Homo sapiens 36080 R-HSA-180709 https://reactome.org/PathwayBrowser/#/R-HSA-180709 Association of multimerized Rev with beta-importin TAS Homo sapiens 36080 R-HSA-180710 https://reactome.org/PathwayBrowser/#/R-HSA-180710 Rev:importin beta:B23 recruited to the nuclear pore IEA Homo sapiens 36080 R-HSA-180725 https://reactome.org/PathwayBrowser/#/R-HSA-180725 Rev associates with B23 TAS Homo sapiens 36080 R-HSA-180728 https://reactome.org/PathwayBrowser/#/R-HSA-180728 Association of Ran-GTP with importin-beta TAS Homo sapiens 36080 R-HSA-180732 https://reactome.org/PathwayBrowser/#/R-HSA-180732 Translocation of Rev:importin-beta:B23 to the nucleus IEA Homo sapiens 36080 R-HSA-180736 https://reactome.org/PathwayBrowser/#/R-HSA-180736 Disassembly of the Rev-importin beta-B23:Ran-GTP complex TAS Homo sapiens 36080 R-HSA-180739 https://reactome.org/PathwayBrowser/#/R-HSA-180739 Association of RanBP1 with Ran-GTP:CRM1:Rev:mRNA complex TAS Homo sapiens 36080 R-HSA-180885 https://reactome.org/PathwayBrowser/#/R-HSA-180885 Rev multimer-bound HIV mRNA associates with Crm1 TAS Homo sapiens 36080 R-HSA-1861595 https://reactome.org/PathwayBrowser/#/R-HSA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner TAS Homo sapiens 36080 R-HSA-1861621 https://reactome.org/PathwayBrowser/#/R-HSA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag TAS Homo sapiens 36080 R-HSA-187746 https://reactome.org/PathwayBrowser/#/R-HSA-187746 RIT/RIN are activated IEA Homo sapiens 36080 R-HSA-190519 https://reactome.org/PathwayBrowser/#/R-HSA-190519 Internalization of gap junction plaques TAS Homo sapiens 36080 R-HSA-190520 https://reactome.org/PathwayBrowser/#/R-HSA-190520 Association of Golgi transport vesicles with microtubules TAS Homo sapiens 36080 R-HSA-190829 https://reactome.org/PathwayBrowser/#/R-HSA-190829 Lysosomal degradation of gap junction plaques TAS Homo sapiens 36080 R-HSA-190877 https://reactome.org/PathwayBrowser/#/R-HSA-190877 Insertion of connexons into the plasma membrane resulting in the formation of hemi-channels IEA Homo sapiens 36080 R-HSA-191737 https://reactome.org/PathwayBrowser/#/R-HSA-191737 Docking of connexons into junctional, double-membrane spanning channels IEA Homo sapiens 36080 R-HSA-193636 https://reactome.org/PathwayBrowser/#/R-HSA-193636 p75NTR interacts with the NOGO receptor TAS Homo sapiens 36080 R-HSA-193647 https://reactome.org/PathwayBrowser/#/R-HSA-193647 IRAK is activated IEA Homo sapiens 36080 R-HSA-193655 https://reactome.org/PathwayBrowser/#/R-HSA-193655 Myelin components can interact with p75NTR:NgR:LINGO1 TAS Homo sapiens 36080 R-HSA-193696 https://reactome.org/PathwayBrowser/#/R-HSA-193696 The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA TAS Homo sapiens 36080 R-HSA-196017 https://reactome.org/PathwayBrowser/#/R-HSA-196017 Dynamin is recruited to the gap junction plaque TAS Homo sapiens 36080 R-HSA-196026 https://reactome.org/PathwayBrowser/#/R-HSA-196026 Dab2 is recruited to the junctional plaques TAS Homo sapiens 36080 R-HSA-1980118 https://reactome.org/PathwayBrowser/#/R-HSA-1980118 ARRB mediates NOTCH1 ubiquitination IEA Homo sapiens 36080 R-HSA-198955 https://reactome.org/PathwayBrowser/#/R-HSA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I TAS Homo sapiens 36080 R-HSA-199161 https://reactome.org/PathwayBrowser/#/R-HSA-199161 Fc gamma receptors interact with antigen-bound IgG TAS Homo sapiens 36080 R-HSA-199518 https://reactome.org/PathwayBrowser/#/R-HSA-199518 C3d-complexed antigen binds to complement receptor TAS Homo sapiens 36080 R-HSA-2002466 https://reactome.org/PathwayBrowser/#/R-HSA-2002466 Formation of allysine by LOX TAS Homo sapiens 36080 R-HSA-200423 https://reactome.org/PathwayBrowser/#/R-HSA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis TAS Homo sapiens 36080 R-HSA-202165 https://reactome.org/PathwayBrowser/#/R-HSA-202165 Phosphorylation of ITAM motifs in CD3 complexes TAS Homo sapiens 36080 R-HSA-202168 https://reactome.org/PathwayBrowser/#/R-HSA-202168 Phosphorylation of ZAP-70 by Lck TAS Homo sapiens 36080 R-HSA-202174 https://reactome.org/PathwayBrowser/#/R-HSA-202174 Activation of ZAP-70 TAS Homo sapiens 36080 R-HSA-202214 https://reactome.org/PathwayBrowser/#/R-HSA-202214 Dephosphorylation of Lck-pY505 by CD45 TAS Homo sapiens 36080 R-HSA-202216 https://reactome.org/PathwayBrowser/#/R-HSA-202216 Phosphorylation of SLP-76 TAS Homo sapiens 36080 R-HSA-202233 https://reactome.org/PathwayBrowser/#/R-HSA-202233 Inactivation of Lck by Csk TAS Homo sapiens 36080 R-HSA-202245 https://reactome.org/PathwayBrowser/#/R-HSA-202245 Phosphorylation of TBSMs in LAT TAS Homo sapiens 36080 R-HSA-202248 https://reactome.org/PathwayBrowser/#/R-HSA-202248 Phosphorylation of PLC-gamma1 TAS Homo sapiens 36080 R-HSA-202291 https://reactome.org/PathwayBrowser/#/R-HSA-202291 Activation of Lck TAS Homo sapiens 36080 R-HSA-202307 https://reactome.org/PathwayBrowser/#/R-HSA-202307 Change of PKC theta conformation TAS Homo sapiens 36080 R-HSA-202344 https://reactome.org/PathwayBrowser/#/R-HSA-202344 Recruitment of ZAP-70 to phosphorylated ITAMs TAS Homo sapiens 36080 R-HSA-202453 https://reactome.org/PathwayBrowser/#/R-HSA-202453 Auto-ubiquitination of TRAF6 TAS Homo sapiens 36080 R-HSA-202534 https://reactome.org/PathwayBrowser/#/R-HSA-202534 Ubiquitination of NEMO by TRAF6 TAS Homo sapiens 36080 R-HSA-2029268 https://reactome.org/PathwayBrowser/#/R-HSA-2029268 Phosphorylation and activation of PLCG TAS Homo sapiens 36080 R-HSA-2029270 https://reactome.org/PathwayBrowser/#/R-HSA-2029270 Recruitment of PLCgamma to membrane TAS Homo sapiens 36080 R-HSA-2029271 https://reactome.org/PathwayBrowser/#/R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 36080 R-HSA-2029272 https://reactome.org/PathwayBrowser/#/R-HSA-2029272 Release of PLCG from FCGR TAS Homo sapiens 36080 R-HSA-2029273 https://reactome.org/PathwayBrowser/#/R-HSA-2029273 PI3K binds to p-6Y-SYK TAS Homo sapiens 36080 R-HSA-2029445 https://reactome.org/PathwayBrowser/#/R-HSA-2029445 An unknown GEF exchanges GTP for GDP on CDC42:GDP TAS Homo sapiens 36080 R-HSA-2029449 https://reactome.org/PathwayBrowser/#/R-HSA-2029449 Phosphorylation of SYK by Src kinases IEA Homo sapiens 36080 R-HSA-2029451 https://reactome.org/PathwayBrowser/#/R-HSA-2029451 Activation of RAC1 by VAV TAS Homo sapiens 36080 R-HSA-2029452 https://reactome.org/PathwayBrowser/#/R-HSA-2029452 Recruitment of SYK to phosphorylated ITAMs TAS Homo sapiens 36080 R-HSA-2029453 https://reactome.org/PathwayBrowser/#/R-HSA-2029453 Phosphorylation of VAV TAS Homo sapiens 36080 R-HSA-2029455 https://reactome.org/PathwayBrowser/#/R-HSA-2029455 Cross-linking of FCGRIA with IgG-coated Ag TAS Homo sapiens 36080 R-HSA-2029457 https://reactome.org/PathwayBrowser/#/R-HSA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag TAS Homo sapiens 36080 R-HSA-2029458 https://reactome.org/PathwayBrowser/#/R-HSA-2029458 Recruitment of VAV1 to p-6Y-SYK TAS Homo sapiens 36080 R-HSA-2029459 https://reactome.org/PathwayBrowser/#/R-HSA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts TAS Homo sapiens 36080 R-HSA-2029466 https://reactome.org/PathwayBrowser/#/R-HSA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin TAS Homo sapiens 36080 R-HSA-2029467 https://reactome.org/PathwayBrowser/#/R-HSA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO TAS Homo sapiens 36080 R-HSA-2029473 https://reactome.org/PathwayBrowser/#/R-HSA-2029473 Branching and elongation of mother and daughter filaments TAS Homo sapiens 36080 R-HSA-2029476 https://reactome.org/PathwayBrowser/#/R-HSA-2029476 Role of myosins in phagosome formation TAS Homo sapiens 36080 R-HSA-203973 https://reactome.org/PathwayBrowser/#/R-HSA-203973 Vesicle budding TAS Homo sapiens 36080 R-HSA-204008 https://reactome.org/PathwayBrowser/#/R-HSA-204008 SEC31:SEC13 and v-SNARE recruitment TAS Homo sapiens 36080 R-HSA-2065233 https://reactome.org/PathwayBrowser/#/R-HSA-2065233 CS is cleaved from its proteoglycan TAS Homo sapiens 36080 R-HSA-2067713 https://reactome.org/PathwayBrowser/#/R-HSA-2067713 GP369 inhibits activation of amplified FGFR2 signaling TAS Homo sapiens 36080 R-HSA-2077421 https://reactome.org/PathwayBrowser/#/R-HSA-2077421 FP-1039 acts as a ligand-trap for FGFR2b-binding ligands in endometrial cancer TAS Homo sapiens 36080 R-HSA-2090085 https://reactome.org/PathwayBrowser/#/R-HSA-2090085 HGSNAT oligomer acetylates Heparan chain(1) TAS Homo sapiens 36080 R-HSA-209573 https://reactome.org/PathwayBrowser/#/R-HSA-209573 p75NTR:NgR complex interacts with the axonal inhibitor LINGO1 TAS Homo sapiens 36080 R-HSA-211239 https://reactome.org/PathwayBrowser/#/R-HSA-211239 Association of DFF40 with chromatin TAS Homo sapiens 36080 R-HSA-211247 https://reactome.org/PathwayBrowser/#/R-HSA-211247 Cleavage of DNA by DFF40 TAS Homo sapiens 36080 R-HSA-211734 https://reactome.org/PathwayBrowser/#/R-HSA-211734 Ubiquitination of PAK-2p34 IEA Homo sapiens 36080 R-HSA-2129353 https://reactome.org/PathwayBrowser/#/R-HSA-2129353 Tropoelastin associates with microfibrils TAS Homo sapiens 36080 R-HSA-2129362 https://reactome.org/PathwayBrowser/#/R-HSA-2129362 Fibrillin microfibril assembly TAS Homo sapiens 36080 R-HSA-2129375 https://reactome.org/PathwayBrowser/#/R-HSA-2129375 Elastin cross-linking by lysyl oxidase TAS Homo sapiens 36080 R-HSA-2129385 https://reactome.org/PathwayBrowser/#/R-HSA-2129385 MFAP2, MFAP5 bind microfibrils TAS Homo sapiens 36080 R-HSA-2130627 https://reactome.org/PathwayBrowser/#/R-HSA-2130627 MHC class II antigen internalization TAS Homo sapiens 36080 R-HSA-216040 https://reactome.org/PathwayBrowser/#/R-HSA-216040 Collagen type IV networks bind integrins alpha1beta1, alpha2beta1 IEA Homo sapiens 36080 R-HSA-216043 https://reactome.org/PathwayBrowser/#/R-HSA-216043 Collagen type II binds integrin alpha10beta1 TAS Homo sapiens 36080 R-HSA-216045 https://reactome.org/PathwayBrowser/#/R-HSA-216045 Collagen type I binds integrin alpha11beta1 TAS Homo sapiens 36080 R-HSA-216050 https://reactome.org/PathwayBrowser/#/R-HSA-216050 Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix TAS Homo sapiens 36080 R-HSA-216072 https://reactome.org/PathwayBrowser/#/R-HSA-216072 Interaction of integrin alphaIIbbeta3 with von Willebrand factor TAS Homo sapiens 36080 R-HSA-2161193 https://reactome.org/PathwayBrowser/#/R-HSA-2161193 abacavir + AMP => abacavir monophosphate + adenosine TAS Homo sapiens 36080 R-HSA-2161282 https://reactome.org/PathwayBrowser/#/R-HSA-2161282 Elastic fibres bind associated proteins TAS Homo sapiens 36080 R-HSA-2161732 https://reactome.org/PathwayBrowser/#/R-HSA-2161732 TXB2 is converted to 11dh-TXB2 by TXDH TAS Homo sapiens 36080 R-HSA-2161776 https://reactome.org/PathwayBrowser/#/R-HSA-2161776 5S-HETE is oxidised to 5-oxoETE by 5-HEDH TAS Homo sapiens 36080 R-HSA-2161789 https://reactome.org/PathwayBrowser/#/R-HSA-2161789 15S-HETE is oxidised to 15-oxoETE by 15-HEDH TAS Homo sapiens 36080 R-HSA-2161868 https://reactome.org/PathwayBrowser/#/R-HSA-2161868 EXD4 is converted to EXE4 by DPEP TAS Homo sapiens 36080 R-HSA-2161945 https://reactome.org/PathwayBrowser/#/R-HSA-2161945 EXC4 is converted to EXD4 by GGT TAS Homo sapiens 36080 R-HSA-2161949 https://reactome.org/PathwayBrowser/#/R-HSA-2161949 HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH TAS Homo sapiens 36080 R-HSA-2161979 https://reactome.org/PathwayBrowser/#/R-HSA-2161979 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH TAS Homo sapiens 36080 R-HSA-2162092 https://reactome.org/PathwayBrowser/#/R-HSA-2162092 carbovir monophosphate + ATP => carbovir diphosphate + ADP IEA Homo sapiens 36080 R-HSA-2162099 https://reactome.org/PathwayBrowser/#/R-HSA-2162099 abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP TAS Homo sapiens 36080 R-HSA-2162191 https://reactome.org/PathwayBrowser/#/R-HSA-2162191 Unknown enzyme hydroxylates DMPhOH IEA Homo sapiens 36080 R-HSA-2162195 https://reactome.org/PathwayBrowser/#/R-HSA-2162195 Unknown enzyme decarboxylates MHDB IEA Homo sapiens 36080 R-HSA-2168038 https://reactome.org/PathwayBrowser/#/R-HSA-2168038 Collagen type XV restin release TAS Homo sapiens 36080 R-HSA-2168923 https://reactome.org/PathwayBrowser/#/R-HSA-2168923 Collagen type XVIII endostatin release TAS Homo sapiens 36080 R-HSA-2197690 https://reactome.org/PathwayBrowser/#/R-HSA-2197690 Detachment of WASP/WAVE TAS Homo sapiens 36080 R-HSA-2197697 https://reactome.org/PathwayBrowser/#/R-HSA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR TAS Homo sapiens 36080 R-HSA-2213192 https://reactome.org/PathwayBrowser/#/R-HSA-2213192 Hemidesmosome formation TAS Homo sapiens 36080 R-HSA-2213195 https://reactome.org/PathwayBrowser/#/R-HSA-2213195 Formation of anchoring fibrils TAS Homo sapiens 36080 R-HSA-2213201 https://reactome.org/PathwayBrowser/#/R-HSA-2213201 Formation of collagen fibres TAS Homo sapiens 36080 R-HSA-2213205 https://reactome.org/PathwayBrowser/#/R-HSA-2213205 Type XII and XIV collagens associate with type I and type II fibrils. TAS Homo sapiens 36080 R-HSA-2213207 https://reactome.org/PathwayBrowser/#/R-HSA-2213207 Formation of collagen networks TAS Homo sapiens 36080 R-HSA-2213208 https://reactome.org/PathwayBrowser/#/R-HSA-2213208 Type X collagen associates with collagen type II fibrils TAS Homo sapiens 36080 R-HSA-2213210 https://reactome.org/PathwayBrowser/#/R-HSA-2213210 Collagen IX is cross-linked to the surface of collagen type II fibrils TAS Homo sapiens 36080 R-HSA-2213240 https://reactome.org/PathwayBrowser/#/R-HSA-2213240 Reduction of disulphide bonds in MHC II antigens TAS Homo sapiens 36080 R-HSA-2213248 https://reactome.org/PathwayBrowser/#/R-HSA-2213248 Transport of antigen loaded MHC II molecules to surface TAS Homo sapiens 36080 R-HSA-2243926 https://reactome.org/PathwayBrowser/#/R-HSA-2243926 Formation of histidino-hydroxylysinonorleucine cross-links TAS Homo sapiens 36080 R-HSA-2243931 https://reactome.org/PathwayBrowser/#/R-HSA-2243931 Formation of dehydro-lysinonorleucine cross-links TAS Homo sapiens 36080 R-HSA-2250301 https://reactome.org/PathwayBrowser/#/R-HSA-2250301 Formation of lysyl-pyrrole cross-links TAS Homo sapiens 36080 R-HSA-2272795 https://reactome.org/PathwayBrowser/#/R-HSA-2272795 Interaction of DAP12 and KIR2DS1 TAS Homo sapiens 36080 R-HSA-2299620 https://reactome.org/PathwayBrowser/#/R-HSA-2299620 Collagen XI cross-links with collagen II TAS Homo sapiens 36080 R-HSA-2316347 https://reactome.org/PathwayBrowser/#/R-HSA-2316347 RAB4A:GTP binds KIF3 and activates KIF3 IEA Homo sapiens 36080 R-HSA-2316349 https://reactome.org/PathwayBrowser/#/R-HSA-2316349 RALA:GTP binds MYO1C:CALM1 and activates MYO1C IEA Homo sapiens 36080 R-HSA-2316352 https://reactome.org/PathwayBrowser/#/R-HSA-2316352 SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane IEA Homo sapiens 36080 R-HSA-2327695 https://reactome.org/PathwayBrowser/#/R-HSA-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 TAS Homo sapiens 36080 R-HSA-2327733 https://reactome.org/PathwayBrowser/#/R-HSA-2327733 FN1 binds Collagen types I-V, VII TAS Homo sapiens 36080 R-HSA-2327738 https://reactome.org/PathwayBrowser/#/R-HSA-2327738 DDR1 binds collagen type I, II, III, IV, V, XI fibrils TAS Homo sapiens 36080 R-HSA-2327746 https://reactome.org/PathwayBrowser/#/R-HSA-2327746 FN1 aggregation TAS Homo sapiens 36080 R-HSA-2327909 https://reactome.org/PathwayBrowser/#/R-HSA-2327909 DCN binds collagen I, II, III, VI fibrils TAS Homo sapiens 36080 R-HSA-2328033 https://reactome.org/PathwayBrowser/#/R-HSA-2328033 Fibrillin-1 binds latent TGF-beta TAS Homo sapiens 36080 R-HSA-2328037 https://reactome.org/PathwayBrowser/#/R-HSA-2328037 Fibrillin-1 binds integrins TAS Homo sapiens 36080 R-HSA-2328048 https://reactome.org/PathwayBrowser/#/R-HSA-2328048 Emilin is found in elastic fibres IEA Homo sapiens 36080 R-HSA-2328145 https://reactome.org/PathwayBrowser/#/R-HSA-2328145 Laminin-111 binds collagen type IV IEA Homo sapiens 36080 R-HSA-2395223 https://reactome.org/PathwayBrowser/#/R-HSA-2395223 Formation of hydroxylysyl-pyridinoline cross-links TAS Homo sapiens 36080 R-HSA-2395257 https://reactome.org/PathwayBrowser/#/R-HSA-2395257 Formation of dehydro-hydroxylysino-norleucine cross-links TAS Homo sapiens 36080 R-HSA-2395302 https://reactome.org/PathwayBrowser/#/R-HSA-2395302 Formation of hydroxylysino-5-ketonorleucine cross-links TAS Homo sapiens 36080 R-HSA-2395314 https://reactome.org/PathwayBrowser/#/R-HSA-2395314 Formation of lysino-5-ketonorleucine cross-links TAS Homo sapiens 36080 R-HSA-2395322 https://reactome.org/PathwayBrowser/#/R-HSA-2395322 Formation of lysyl-pyridinoline cross-links TAS Homo sapiens 36080 R-HSA-2395324 https://reactome.org/PathwayBrowser/#/R-HSA-2395324 Formation of hydroxylysyl-pyrrole cross-links TAS Homo sapiens 36080 R-HSA-2395340 https://reactome.org/PathwayBrowser/#/R-HSA-2395340 Formation of hydroxyallysine by LOX TAS Homo sapiens 36080 R-HSA-2396234 https://reactome.org/PathwayBrowser/#/R-HSA-2396234 Collagen type VII binds laminin-322 and collagen IV TAS Homo sapiens 36080 R-HSA-2396337 https://reactome.org/PathwayBrowser/#/R-HSA-2396337 HSPG2 binds FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer TAS Homo sapiens 36080 R-HSA-2396370 https://reactome.org/PathwayBrowser/#/R-HSA-2396370 VTN binds collagens II, III and V TAS Homo sapiens 36080 R-HSA-2396399 https://reactome.org/PathwayBrowser/#/R-HSA-2396399 Fibrillins bind BMPs TAS Homo sapiens 36080 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 36080 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 36080 R-HSA-2408530 https://reactome.org/PathwayBrowser/#/R-HSA-2408530 MeSeH is hydrolysed to H2Se by methylselenol demethylase IEA Homo sapiens 36080 R-HSA-2408536 https://reactome.org/PathwayBrowser/#/R-HSA-2408536 H2Se is methylated to MeSeH by H2Se methyltransferase IEA Homo sapiens 36080 R-HSA-2408541 https://reactome.org/PathwayBrowser/#/R-HSA-2408541 MeSeH is methylated to Me2Se by MeSeH methyltransferase IEA Homo sapiens 36080 R-HSA-2408548 https://reactome.org/PathwayBrowser/#/R-HSA-2408548 PAPSe is reduced to SeO3(2-) by PAPSe reductase IEA Homo sapiens 36080 R-HSA-2424243 https://reactome.org/PathwayBrowser/#/R-HSA-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ TAS Homo sapiens 36080 R-HSA-2424252 https://reactome.org/PathwayBrowser/#/R-HSA-2424252 COMP binds collagen, fibronectin, aggrecan and matrilins TAS Homo sapiens 36080 R-HSA-2426450 https://reactome.org/PathwayBrowser/#/R-HSA-2426450 Laminins:Nidogens binds collagen type IV networks TAS Homo sapiens 36080 R-HSA-2426676 https://reactome.org/PathwayBrowser/#/R-HSA-2426676 Formation of laminin networks IEA Homo sapiens 36080 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 36080 R-HSA-2454192 https://reactome.org/PathwayBrowser/#/R-HSA-2454192 Allergen dependent IgE bound FCERI aggregation TAS Homo sapiens 36080 R-HSA-2454208 https://reactome.org/PathwayBrowser/#/R-HSA-2454208 Phosphorylation of beta and gamma subunits by LYN TAS Homo sapiens 36080 R-HSA-2454239 https://reactome.org/PathwayBrowser/#/R-HSA-2454239 Phosphorylation of SYK IEA Homo sapiens 36080 R-HSA-2454240 https://reactome.org/PathwayBrowser/#/R-HSA-2454240 Recruitment of SYK to p-FCERI gamma subunit TAS Homo sapiens 36080 R-HSA-2465883 https://reactome.org/PathwayBrowser/#/R-HSA-2465883 VTN binds collagens I, IV and VI IEA Homo sapiens 36080 R-HSA-2465890 https://reactome.org/PathwayBrowser/#/R-HSA-2465890 DDR2 binds collagen type I, II, III, V, X fibrils TAS Homo sapiens 36080 R-HSA-2465921 https://reactome.org/PathwayBrowser/#/R-HSA-2465921 11cRDH oxidises 11cROL to 11cRAL TAS Homo sapiens 36080 R-HSA-2465926 https://reactome.org/PathwayBrowser/#/R-HSA-2465926 An atROL isomerase isomerises atROL to 11cROL IEA Homo sapiens 36080 R-HSA-2465941 https://reactome.org/PathwayBrowser/#/R-HSA-2465941 A REH hydrolyses 11cRE to 11cROL IEA Homo sapiens 36080 R-HSA-2466106 https://reactome.org/PathwayBrowser/#/R-HSA-2466106 BGN binds Collagen types I, VI, (IX) TAS Homo sapiens 36080 R-HSA-2466238 https://reactome.org/PathwayBrowser/#/R-HSA-2466238 BGN binds Collagen types II, III IEA Homo sapiens 36080 R-HSA-2467665 https://reactome.org/PathwayBrowser/#/R-HSA-2467665 AGRN binds Beta amyloid fibril via GAG chains TAS Homo sapiens 36080 R-HSA-2467809 https://reactome.org/PathwayBrowser/#/R-HSA-2467809 ESPL1 (Separase) cleaves centromeric cohesin TAS Homo sapiens 36080 R-HSA-2467811 https://reactome.org/PathwayBrowser/#/R-HSA-2467811 Separation of sister chromatids TAS Homo sapiens 36080 R-HSA-2468287 https://reactome.org/PathwayBrowser/#/R-HSA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres TAS Homo sapiens 36080 R-HSA-2470555 https://reactome.org/PathwayBrowser/#/R-HSA-2470555 Collagen type X binds Integrin alpha2beta1 IEA Homo sapiens 36080 R-HSA-2473584 https://reactome.org/PathwayBrowser/#/R-HSA-2473584 Collagen type III degradation by MMP15 TAS Homo sapiens 36080 R-HSA-2473594 https://reactome.org/PathwayBrowser/#/R-HSA-2473594 Collagen type II degradation by MMP15 TAS Homo sapiens 36080 R-HSA-2473596 https://reactome.org/PathwayBrowser/#/R-HSA-2473596 Collagen type I degradation by MMP15 TAS Homo sapiens 36080 R-HSA-2482180 https://reactome.org/PathwayBrowser/#/R-HSA-2482180 Collagen type VIII degradation by ELANE IEA Homo sapiens 36080 R-HSA-2484822 https://reactome.org/PathwayBrowser/#/R-HSA-2484822 Kinetochore assembly TAS Homo sapiens 36080 R-HSA-2484882 https://reactome.org/PathwayBrowser/#/R-HSA-2484882 Collagen type X degradation by MMP3, 13 IEA Homo sapiens 36080 R-HSA-2485111 https://reactome.org/PathwayBrowser/#/R-HSA-2485111 Collagen type III degradation by MMP10 IEA Homo sapiens 36080 R-HSA-2485148 https://reactome.org/PathwayBrowser/#/R-HSA-2485148 Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13 TAS Homo sapiens 36080 R-HSA-2514772 https://reactome.org/PathwayBrowser/#/R-HSA-2514772 Fibrillin-1 degradation by MMP3, CTSK, CTSL2 TAS Homo sapiens 36080 R-HSA-2514790 https://reactome.org/PathwayBrowser/#/R-HSA-2514790 Elastin degradation by MMP14 TAS Homo sapiens 36080 R-HSA-2514823 https://reactome.org/PathwayBrowser/#/R-HSA-2514823 Fibrillin-1 degradation by ELANE IEA Homo sapiens 36080 R-HSA-2514831 https://reactome.org/PathwayBrowser/#/R-HSA-2514831 Fibrillin-1 degradation by MMP14 TAS Homo sapiens 36080 R-HSA-2529015 https://reactome.org/PathwayBrowser/#/R-HSA-2529015 Dephosphorylation of CK2-modified condensin I TAS Homo sapiens 36080 R-HSA-2533944 https://reactome.org/PathwayBrowser/#/R-HSA-2533944 Fibronectin degradation by MMP10 IEA Homo sapiens 36080 R-HSA-2533950 https://reactome.org/PathwayBrowser/#/R-HSA-2533950 Fibronectin degradation by MMP14 TAS Homo sapiens 36080 R-HSA-2534040 https://reactome.org/PathwayBrowser/#/R-HSA-2534040 Unknown NAT N-acylates Gly in GNAT1 IEA Homo sapiens 36080 R-HSA-2537499 https://reactome.org/PathwayBrowser/#/R-HSA-2537499 Gelatin degradation by MMP19 IEA Homo sapiens 36080 R-HSA-2537665 https://reactome.org/PathwayBrowser/#/R-HSA-2537665 Fibulin-1 and -2 bind fibronectin TAS Homo sapiens 36080 R-HSA-2559639 https://reactome.org/PathwayBrowser/#/R-HSA-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin TAS Homo sapiens 36080 R-HSA-265166 https://reactome.org/PathwayBrowser/#/R-HSA-265166 Exocytosis of Insulin IEA Homo sapiens 36080 R-HSA-265425 https://reactome.org/PathwayBrowser/#/R-HSA-265425 Interaction of integrin alphaVbeta3 with von Willbrand Factor TAS Homo sapiens 36080 R-HSA-2681681 https://reactome.org/PathwayBrowser/#/R-HSA-2681681 Tenascins C, R, (X, N) bind fibronectin matrix TAS Homo sapiens 36080 R-HSA-2730833 https://reactome.org/PathwayBrowser/#/R-HSA-2730833 Phosphorylation of TEC kinases by p-SYK TAS Homo sapiens 36080 R-HSA-2730836 https://reactome.org/PathwayBrowser/#/R-HSA-2730836 Interaction of BCL10:MALT1 with CARMA1 to form CBM complex IEA Homo sapiens 36080 R-HSA-2730843 https://reactome.org/PathwayBrowser/#/R-HSA-2730843 Phosphorylation of LAT by p-SYK TAS Homo sapiens 36080 R-HSA-2730851 https://reactome.org/PathwayBrowser/#/R-HSA-2730851 Phosphorylation of SLP-76 by p-SYK TAS Homo sapiens 36080 R-HSA-2730860 https://reactome.org/PathwayBrowser/#/R-HSA-2730860 Phosphorylation of GAB2 by SYK/FYN IEA Homo sapiens 36080 R-HSA-2730861 https://reactome.org/PathwayBrowser/#/R-HSA-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 TAS Homo sapiens 36080 R-HSA-2730864 https://reactome.org/PathwayBrowser/#/R-HSA-2730864 Recruitment of TRAF6 to CBM complex by binding to MALT1 TAS Homo sapiens 36080 R-HSA-2730876 https://reactome.org/PathwayBrowser/#/R-HSA-2730876 Phosphorylation of IKK-beta by TAK1 TAS Homo sapiens 36080 R-HSA-2730882 https://reactome.org/PathwayBrowser/#/R-HSA-2730882 Phosphorylation of PKC-theta TAS Homo sapiens 36080 R-HSA-2730884 https://reactome.org/PathwayBrowser/#/R-HSA-2730884 Phosphorylation of NTAL by p-SYK/Lyn TAS Homo sapiens 36080 R-HSA-2730886 https://reactome.org/PathwayBrowser/#/R-HSA-2730886 Phosphorylation of SHC by SYK kinase TAS Homo sapiens 36080 R-HSA-2730888 https://reactome.org/PathwayBrowser/#/R-HSA-2730888 Phosphorylation of PLC-gamma IEA Homo sapiens 36080 R-HSA-2730899 https://reactome.org/PathwayBrowser/#/R-HSA-2730899 Oligomerization of BCL10 and MALT1 TAS Homo sapiens 36080 R-HSA-2730900 https://reactome.org/PathwayBrowser/#/R-HSA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 TAS Homo sapiens 36080 R-HSA-2730902 https://reactome.org/PathwayBrowser/#/R-HSA-2730902 Oligomerization of p-CARMA1 TAS Homo sapiens 36080 R-HSA-2730903 https://reactome.org/PathwayBrowser/#/R-HSA-2730903 Oligomerization of TRAF6 TAS Homo sapiens 36080 R-HSA-2730904 https://reactome.org/PathwayBrowser/#/R-HSA-2730904 Auto-ubiquitination of TRAF6 TAS Homo sapiens 36080 R-HSA-2731075 https://reactome.org/PathwayBrowser/#/R-HSA-2731075 Syndecan-1 binds collagen types I, III, V IEA Homo sapiens 36080 R-HSA-2731141 https://reactome.org/PathwayBrowser/#/R-HSA-2731141 Syndecan-1 binds fibronectin TAS Homo sapiens 36080 R-HSA-2855020 https://reactome.org/PathwayBrowser/#/R-HSA-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol TAS Homo sapiens 36080 R-HSA-2993898 https://reactome.org/PathwayBrowser/#/R-HSA-2993898 VRK1/VRK2 phosphorylate BANF1 TAS Homo sapiens 36080 R-HSA-2995376 https://reactome.org/PathwayBrowser/#/R-HSA-2995376 BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins TAS Homo sapiens 36080 R-HSA-3000243 https://reactome.org/PathwayBrowser/#/R-HSA-3000243 Unknown lysosomal protease degrades CBLIF:RCbl to release Cbl TAS Homo sapiens 36080 R-HSA-3000263 https://reactome.org/PathwayBrowser/#/R-HSA-3000263 TCN2:RCbl is degraded to release RCbl TAS Homo sapiens 36080 R-HSA-3065958 https://reactome.org/PathwayBrowser/#/R-HSA-3065958 An unknown protease degrades ACACA TAS Homo sapiens 36080 R-HSA-3065959 https://reactome.org/PathwayBrowser/#/R-HSA-3065959 An unknown protease degrades hCBXs TAS Homo sapiens 36080 R-HSA-3132759 https://reactome.org/PathwayBrowser/#/R-HSA-3132759 TCN1 binds RCbl TAS Homo sapiens 36080 R-HSA-3139027 https://reactome.org/PathwayBrowser/#/R-HSA-3139027 Maturation of HIV Virion TAS Homo sapiens 36080 R-HSA-3295579 https://reactome.org/PathwayBrowser/#/R-HSA-3295579 TRPs transport extracellular Ca2+ to cytosol TAS Homo sapiens 36080 R-HSA-373734 https://reactome.org/PathwayBrowser/#/R-HSA-373734 Nephrin interacts with Podocin TAS Homo sapiens 36080 R-HSA-373736 https://reactome.org/PathwayBrowser/#/R-HSA-373736 Shootin-1 links L1 and retrograde actin flow IEA Homo sapiens 36080 R-HSA-373739 https://reactome.org/PathwayBrowser/#/R-HSA-373739 Ankyrins link voltage-gated sodium and potassium channels to spectrin and L1 IEA Homo sapiens 36080 R-HSA-375151 https://reactome.org/PathwayBrowser/#/R-HSA-375151 Interaction of NCAM1 with collagens TAS Homo sapiens 36080 R-HSA-375302 https://reactome.org/PathwayBrowser/#/R-HSA-375302 Kinetochore capture of astral microtubules TAS Homo sapiens 36080 R-HSA-376149 https://reactome.org/PathwayBrowser/#/R-HSA-376149 Proteolytic processing of SLIT TAS Homo sapiens 36080 R-HSA-3785684 https://reactome.org/PathwayBrowser/#/R-HSA-3785684 Fibronectin degradation by CTSG TAS Homo sapiens 36080 R-HSA-3787997 https://reactome.org/PathwayBrowser/#/R-HSA-3787997 Laminin-332 binds collagen type VII TAS Homo sapiens 36080 R-HSA-3788061 https://reactome.org/PathwayBrowser/#/R-HSA-3788061 Fibronectin degradation by ADAM8 TAS Homo sapiens 36080 R-HSA-380316 https://reactome.org/PathwayBrowser/#/R-HSA-380316 Association of NuMA with microtubules TAS Homo sapiens 36080 R-HSA-380620 https://reactome.org/PathwayBrowser/#/R-HSA-380620 Reuptake of serotonin from the synapse TAS Homo sapiens 36080 R-HSA-381086 https://reactome.org/PathwayBrowser/#/R-HSA-381086 Dissociation of PERK:BiP Heterodimer TAS Homo sapiens 36080 R-HSA-381158 https://reactome.org/PathwayBrowser/#/R-HSA-381158 ATF6:HSPA5 (ATF6-alpha:BiP) dissociates and HSPA5 binds unfolded protein TAS Homo sapiens 36080 R-HSA-381217 https://reactome.org/PathwayBrowser/#/R-HSA-381217 IRE1:BiP dissociates in response to unfolded protein TAS Homo sapiens 36080 R-HSA-382054 https://reactome.org/PathwayBrowser/#/R-HSA-382054 PDGF binds to extracellular matrix proteins TAS Homo sapiens 36080 R-HSA-3858480 https://reactome.org/PathwayBrowser/#/R-HSA-3858480 WNT-dependent phosphorylation of DVL IEA Homo sapiens 36080 R-HSA-389758 https://reactome.org/PathwayBrowser/#/R-HSA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases TAS Homo sapiens 36080 R-HSA-390347 https://reactome.org/PathwayBrowser/#/R-HSA-390347 Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane TAS Homo sapiens 36080 R-HSA-390593 https://reactome.org/PathwayBrowser/#/R-HSA-390593 ATP Hydrolysis By Myosin TAS Homo sapiens 36080 R-HSA-390595 https://reactome.org/PathwayBrowser/#/R-HSA-390595 Calcium Binds Troponin-C TAS Homo sapiens 36080 R-HSA-390597 https://reactome.org/PathwayBrowser/#/R-HSA-390597 Release Of ADP From Myosin TAS Homo sapiens 36080 R-HSA-390598 https://reactome.org/PathwayBrowser/#/R-HSA-390598 Myosin Binds ATP TAS Homo sapiens 36080 R-HSA-391155 https://reactome.org/PathwayBrowser/#/R-HSA-391155 SIRPA binds SFTPA oligomer, SFTPD oligomer TAS Homo sapiens 36080 R-HSA-392751 https://reactome.org/PathwayBrowser/#/R-HSA-392751 L1 linked to actin cytoskeleton by ankyrin TAS Homo sapiens 36080 R-HSA-3928578 https://reactome.org/PathwayBrowser/#/R-HSA-3928578 EPH receptors autophosphorylate TAS Homo sapiens 36080 R-HSA-3928583 https://reactome.org/PathwayBrowser/#/R-HSA-3928583 FYN phosphorylates NMDAR2B IEA Homo sapiens 36080 R-HSA-3928584 https://reactome.org/PathwayBrowser/#/R-HSA-3928584 p-EPHs bind SRC,FYN,YES,LYN IEA Homo sapiens 36080 R-HSA-3928588 https://reactome.org/PathwayBrowser/#/R-HSA-3928588 EPHBs binds PTK2 IEA Homo sapiens 36080 R-HSA-3928591 https://reactome.org/PathwayBrowser/#/R-HSA-3928591 EPH:EFN tetramers oligomerise TAS Homo sapiens 36080 R-HSA-3928592 https://reactome.org/PathwayBrowser/#/R-HSA-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it TAS Homo sapiens 36080 R-HSA-3928595 https://reactome.org/PathwayBrowser/#/R-HSA-3928595 N-WASP binds ARP2/3 and G-actin TAS Homo sapiens 36080 R-HSA-3928598 https://reactome.org/PathwayBrowser/#/R-HSA-3928598 Recruitment of p190RhoGEF to p-FAK TAS Homo sapiens 36080 R-HSA-3928600 https://reactome.org/PathwayBrowser/#/R-HSA-3928600 N-WASP binds ITSN1 IEA Homo sapiens 36080 R-HSA-3928601 https://reactome.org/PathwayBrowser/#/R-HSA-3928601 CDC42 and PIP2 bind WASL, activating it TAS Homo sapiens 36080 R-HSA-3928602 https://reactome.org/PathwayBrowser/#/R-HSA-3928602 NGEF binds EPHA IEA Homo sapiens 36080 R-HSA-3928604 https://reactome.org/PathwayBrowser/#/R-HSA-3928604 SFKs phosphorylate VAV2,3 TAS Homo sapiens 36080 R-HSA-3928607 https://reactome.org/PathwayBrowser/#/R-HSA-3928607 p-EPHs bind VAV2,3 TAS Homo sapiens 36080 R-HSA-3928610 https://reactome.org/PathwayBrowser/#/R-HSA-3928610 PTK2 autophosphorylates at Y397 IEA Homo sapiens 36080 R-HSA-3928612 https://reactome.org/PathwayBrowser/#/R-HSA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 36080 R-HSA-3928617 https://reactome.org/PathwayBrowser/#/R-HSA-3928617 EPHB2 binds KALRN TAS Homo sapiens 36080 R-HSA-3928623 https://reactome.org/PathwayBrowser/#/R-HSA-3928623 EPHBs bind NMDARs IEA Homo sapiens 36080 R-HSA-3928627 https://reactome.org/PathwayBrowser/#/R-HSA-3928627 EPHB phosphorylates TIAM1 TAS Homo sapiens 36080 R-HSA-3928628 https://reactome.org/PathwayBrowser/#/R-HSA-3928628 VAV exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 36080 R-HSA-3928632 https://reactome.org/PathwayBrowser/#/R-HSA-3928632 ITSN1 exchanges GTP for GDP on CDC42, activating it IEA Homo sapiens 36080 R-HSA-3928642 https://reactome.org/PathwayBrowser/#/R-HSA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 36080 R-HSA-3928644 https://reactome.org/PathwayBrowser/#/R-HSA-3928644 EPHB binds ITSN1 IEA Homo sapiens 36080 R-HSA-3928645 https://reactome.org/PathwayBrowser/#/R-HSA-3928645 EPHB:NMDAR binds TIAM1 TAS Homo sapiens 36080 R-HSA-3928648 https://reactome.org/PathwayBrowser/#/R-HSA-3928648 SFKs phosphorylate NGEF IEA Homo sapiens 36080 R-HSA-3928651 https://reactome.org/PathwayBrowser/#/R-HSA-3928651 NGEF exchanges GTP for GDP on RHOA TAS Homo sapiens 36080 R-HSA-3928654 https://reactome.org/PathwayBrowser/#/R-HSA-3928654 Clathrin internalises EPH:EFN complexes TAS Homo sapiens 36080 R-HSA-399995 https://reactome.org/PathwayBrowser/#/R-HSA-399995 Muscarinic Acetylcholine Receptor M3 activates Gq IEA Homo sapiens 36080 R-HSA-400027 https://reactome.org/PathwayBrowser/#/R-HSA-400027 Gq alpha:G beta:G gamma dissociates to Gq alpha:GTP and G beta:G gamma TAS Homo sapiens 36080 R-HSA-400063 https://reactome.org/PathwayBrowser/#/R-HSA-400063 Low conductance potassium channels in pancreatic beta cells open in response to epinephrine IEA Homo sapiens 36080 R-HSA-4084501 https://reactome.org/PathwayBrowser/#/R-HSA-4084501 Collagen type VII binds collagen type IV IEA Homo sapiens 36080 R-HSA-4084903 https://reactome.org/PathwayBrowser/#/R-HSA-4084903 Collagen types VI, IX bind integrin alpha10beta1 TAS Homo sapiens 36080 R-HSA-4084910 https://reactome.org/PathwayBrowser/#/R-HSA-4084910 Collagen type II binds integrin alpha2beta1, alpha1beta1, alpha11beta1 IEA Homo sapiens 36080 R-HSA-4086204 https://reactome.org/PathwayBrowser/#/R-HSA-4086204 IBSP binds collagen type I IEA Homo sapiens 36080 R-HSA-4086216 https://reactome.org/PathwayBrowser/#/R-HSA-4086216 Collagen type VII binds integrin alpha2beta1 TAS Homo sapiens 36080 R-HSA-4093327 https://reactome.org/PathwayBrowser/#/R-HSA-4093327 EPHA binds TIAM1 TAS Homo sapiens 36080 R-HSA-4093330 https://reactome.org/PathwayBrowser/#/R-HSA-4093330 EPHB binds p120-RasGAP IEA Homo sapiens 36080 R-HSA-4093331 https://reactome.org/PathwayBrowser/#/R-HSA-4093331 Ras:GTP binds p120-RasGAP TAS Homo sapiens 36080 R-HSA-4093332 https://reactome.org/PathwayBrowser/#/R-HSA-4093332 p-EPHB phosphorylates SDC2 TAS Homo sapiens 36080 R-HSA-4093336 https://reactome.org/PathwayBrowser/#/R-HSA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 36080 R-HSA-4093339 https://reactome.org/PathwayBrowser/#/R-HSA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it TAS Homo sapiens 36080 R-HSA-4093342 https://reactome.org/PathwayBrowser/#/R-HSA-4093342 SDC2 multimerises TAS Homo sapiens 36080 R-HSA-416530 https://reactome.org/PathwayBrowser/#/R-HSA-416530 FFAR1:FFAR1 ligands activate Gq TAS Homo sapiens 36080 R-HSA-4167501 https://reactome.org/PathwayBrowser/#/R-HSA-4167501 An unknown protease degrades ACACB TAS Homo sapiens 36080 R-HSA-429529 https://reactome.org/PathwayBrowser/#/R-HSA-429529 Thrombin binding to GP1b:IX:V TAS Homo sapiens 36080 R-HSA-430073 https://reactome.org/PathwayBrowser/#/R-HSA-430073 GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress TAS Homo sapiens 36080 R-HSA-430076 https://reactome.org/PathwayBrowser/#/R-HSA-430076 GP1b-IX-V binds 14-3-3-zeta TAS Homo sapiens 36080 R-HSA-430096 https://reactome.org/PathwayBrowser/#/R-HSA-430096 GP1b-IX-V binds filamin TAS Homo sapiens 36080 R-HSA-430347 https://reactome.org/PathwayBrowser/#/R-HSA-430347 MigFilin associates with Filamin and F-actin TAS Homo sapiens 36080 R-HSA-4332388 https://reactome.org/PathwayBrowser/#/R-HSA-4332388 Activation of MAP3K7 in response to WNT TAS Homo sapiens 36080 R-HSA-433725 https://reactome.org/PathwayBrowser/#/R-HSA-433725 Interaction of Afadin with F-actin IEA Homo sapiens 36080 R-HSA-437118 https://reactome.org/PathwayBrowser/#/R-HSA-437118 GPVI stimulates PI3K beta, gamma TAS Homo sapiens 36080 R-HSA-4419986 https://reactome.org/PathwayBrowser/#/R-HSA-4419986 Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL TAS Homo sapiens 36080 R-HSA-443402 https://reactome.org/PathwayBrowser/#/R-HSA-443402 GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K TAS Homo sapiens 36080 R-HSA-443418 https://reactome.org/PathwayBrowser/#/R-HSA-443418 GP1b signaling involves c-Src TAS Homo sapiens 36080 R-HSA-443779 https://reactome.org/PathwayBrowser/#/R-HSA-443779 Linkage of L1 with treadmilling F-actin TAS Homo sapiens 36080 R-HSA-445071 https://reactome.org/PathwayBrowser/#/R-HSA-445071 Reinsertion of L1 into the plasma membrane TAS Homo sapiens 36080 R-HSA-445076 https://reactome.org/PathwayBrowser/#/R-HSA-445076 Phosphorylation of Y1229 in L1 TAS Homo sapiens 36080 R-HSA-445077 https://reactome.org/PathwayBrowser/#/R-HSA-445077 Transport of L1 from C-domain to P-domain IEA Homo sapiens 36080 R-HSA-445085 https://reactome.org/PathwayBrowser/#/R-HSA-445085 Phosphorylation of VAV2 TAS Homo sapiens 36080 R-HSA-445089 https://reactome.org/PathwayBrowser/#/R-HSA-445089 Dephosphorylation of pL1 (Y1176) TAS Homo sapiens 36080 R-HSA-445091 https://reactome.org/PathwayBrowser/#/R-HSA-445091 Phosphorylation of Neurofascin IEA Homo sapiens 36080 R-HSA-446077 https://reactome.org/PathwayBrowser/#/R-HSA-446077 BP230 interacts with keretin K5/K14 TAS Homo sapiens 36080 R-HSA-446209 https://reactome.org/PathwayBrowser/#/R-HSA-446209 Transfer of N-glycan to the protein TAS Homo sapiens 36080 R-HSA-446877 https://reactome.org/PathwayBrowser/#/R-HSA-446877 TRAF6 is K63 poly-ubiquitinated TAS Homo sapiens 36080 R-HSA-450337 https://reactome.org/PathwayBrowser/#/R-HSA-450337 Activated TAK1 phosphorylates MKK4/MKK7 TAS Homo sapiens 36080 R-HSA-450346 https://reactome.org/PathwayBrowser/#/R-HSA-450346 activated human TAK1 phosphorylates MKK3/MKK6 TAS Homo sapiens 36080 R-HSA-450358 https://reactome.org/PathwayBrowser/#/R-HSA-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation TAS Homo sapiens 36080 R-HSA-451418 https://reactome.org/PathwayBrowser/#/R-HSA-451418 Pellino ubiquitinates IRAK1 TAS Homo sapiens 36080 R-HSA-453183 https://reactome.org/PathwayBrowser/#/R-HSA-453183 p-Y348-SYK dissociates TAS Homo sapiens 36080 R-HSA-453200 https://reactome.org/PathwayBrowser/#/R-HSA-453200 SYK autophosphorylates TAS Homo sapiens 36080 R-HSA-4539779 https://reactome.org/PathwayBrowser/#/R-HSA-4539779 Collagen type IV binds integrin alpha10beta1 IEA Homo sapiens 36080 R-HSA-4551570 https://reactome.org/PathwayBrowser/#/R-HSA-4551570 VANGL2 is phosphorylated in response to WNT5A IEA Homo sapiens 36080 R-HSA-4608825 https://reactome.org/PathwayBrowser/#/R-HSA-4608825 DVL2 is phosphorylated after WNT5A binding to FZD TAS Homo sapiens 36080 R-HSA-4793947 https://reactome.org/PathwayBrowser/#/R-HSA-4793947 Defective MOGS does not cleave glucose from an N-glycosylated protein TAS Homo sapiens 36080 R-HSA-4793949 https://reactome.org/PathwayBrowser/#/R-HSA-4793949 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (a branch) TAS Homo sapiens 36080 R-HSA-5218829 https://reactome.org/PathwayBrowser/#/R-HSA-5218829 VEGF induces CDC42 activation by unknown mechanism TAS Homo sapiens 36080 R-HSA-5218891 https://reactome.org/PathwayBrowser/#/R-HSA-5218891 RIPK1:RIPK3 oligomer binds MLKL TAS Homo sapiens 36080 R-HSA-5218905 https://reactome.org/PathwayBrowser/#/R-HSA-5218905 RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils TAS Homo sapiens 36080 R-HSA-5218906 https://reactome.org/PathwayBrowser/#/R-HSA-5218906 RIPK3 phosphorylates MLKL TAS Homo sapiens 36080 R-HSA-5218916 https://reactome.org/PathwayBrowser/#/R-HSA-5218916 p-MAPK2/3 phosphorylates HSP27 TAS Homo sapiens 36080 R-HSA-5229194 https://reactome.org/PathwayBrowser/#/R-HSA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation TAS Homo sapiens 36080 R-HSA-5246693 https://reactome.org/PathwayBrowser/#/R-HSA-5246693 APC is K63-polyubiquitinated TAS Homo sapiens 36080 R-HSA-532667 https://reactome.org/PathwayBrowser/#/R-HSA-532667 Removal of the second glucose by glucosidase II TAS Homo sapiens 36080 R-HSA-532678 https://reactome.org/PathwayBrowser/#/R-HSA-532678 Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase TAS Homo sapiens 36080 R-HSA-5340124 https://reactome.org/PathwayBrowser/#/R-HSA-5340124 CSN polymer binds CaPO4 TAS Homo sapiens 36080 R-HSA-535717 https://reactome.org/PathwayBrowser/#/R-HSA-535717 Binding of calnexin/calreticulin to the unfolded protein TAS Homo sapiens 36080 R-HSA-5357757 https://reactome.org/PathwayBrowser/#/R-HSA-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 TAS Homo sapiens 36080 R-HSA-5357927 https://reactome.org/PathwayBrowser/#/R-HSA-5357927 MLKL oligomerizes TAS Homo sapiens 36080 R-HSA-5432814 https://reactome.org/PathwayBrowser/#/R-HSA-5432814 SFTPA/SFTPD binds TLR2:TLR1 TAS Homo sapiens 36080 R-HSA-5432852 https://reactome.org/PathwayBrowser/#/R-HSA-5432852 SFTPA/SFTPD binds TLR4:LY96 TAS Homo sapiens 36080 R-HSA-5433066 https://reactome.org/PathwayBrowser/#/R-HSA-5433066 Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C TAS Homo sapiens 36080 R-HSA-548884 https://reactome.org/PathwayBrowser/#/R-HSA-548884 UGGT1,2 transfers glucose from DbGP to (un)folded protein:(GlcNAc)2 (Man)8b TAS Homo sapiens 36080 R-HSA-548890 https://reactome.org/PathwayBrowser/#/R-HSA-548890 Removal of the third glucose by glucosidase II and release from the chaperone TAS Homo sapiens 36080 R-HSA-5607732 https://reactome.org/PathwayBrowser/#/R-HSA-5607732 K63polyUb-TAK1 autophosphorylates TAS Homo sapiens 36080 R-HSA-5607733 https://reactome.org/PathwayBrowser/#/R-HSA-5607733 BCL10 binds CARD9 TAS Homo sapiens 36080 R-HSA-5607736 https://reactome.org/PathwayBrowser/#/R-HSA-5607736 MALT1 oligomerizes TAS Homo sapiens 36080 R-HSA-5607737 https://reactome.org/PathwayBrowser/#/R-HSA-5607737 BCL10 oligomerizes TAS Homo sapiens 36080 R-HSA-5607742 https://reactome.org/PathwayBrowser/#/R-HSA-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta TAS Homo sapiens 36080 R-HSA-5607744 https://reactome.org/PathwayBrowser/#/R-HSA-5607744 MALT1 binds BCL10 TAS Homo sapiens 36080 R-HSA-5607747 https://reactome.org/PathwayBrowser/#/R-HSA-5607747 TRAF6 binds MALT1 oligomers TAS Homo sapiens 36080 R-HSA-5607751 https://reactome.org/PathwayBrowser/#/R-HSA-5607751 TRAF6 oligomerizes TAS Homo sapiens 36080 R-HSA-5607753 https://reactome.org/PathwayBrowser/#/R-HSA-5607753 CARD9 oligomerizes TAS Homo sapiens 36080 R-HSA-5607756 https://reactome.org/PathwayBrowser/#/R-HSA-5607756 TRAF6 oligomer autoubiquitinates TAS Homo sapiens 36080 R-HSA-5607757 https://reactome.org/PathwayBrowser/#/R-HSA-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 TAS Homo sapiens 36080 R-HSA-5607759 https://reactome.org/PathwayBrowser/#/R-HSA-5607759 TRIKA2 binds K63polyUb-TRAF6 oligomer TAS Homo sapiens 36080 R-HSA-5610733 https://reactome.org/PathwayBrowser/#/R-HSA-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules TAS Homo sapiens 36080 R-HSA-5610767 https://reactome.org/PathwayBrowser/#/R-HSA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip TAS Homo sapiens 36080 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 36080 R-HSA-5618328 https://reactome.org/PathwayBrowser/#/R-HSA-5618328 ATAT acetylates microtubules TAS Homo sapiens 36080 R-HSA-5618331 https://reactome.org/PathwayBrowser/#/R-HSA-5618331 HDAC6 deacetylates microtubules TAS Homo sapiens 36080 R-HSA-5620975 https://reactome.org/PathwayBrowser/#/R-HSA-5620975 MLKL binds PIPs TAS Homo sapiens 36080 R-HSA-5624949 https://reactome.org/PathwayBrowser/#/R-HSA-5624949 Assembly of the anterograde IFT train TAS Homo sapiens 36080 R-HSA-5624952 https://reactome.org/PathwayBrowser/#/R-HSA-5624952 Assembly of the retrograde IFT train TAS Homo sapiens 36080 R-HSA-5625416 https://reactome.org/PathwayBrowser/#/R-HSA-5625416 Anterograde IFT TAS Homo sapiens 36080 R-HSA-5625421 https://reactome.org/PathwayBrowser/#/R-HSA-5625421 The anterograde IFT train dissociates TAS Homo sapiens 36080 R-HSA-5625424 https://reactome.org/PathwayBrowser/#/R-HSA-5625424 The retrograde IFT train dissociates TAS Homo sapiens 36080 R-HSA-5625426 https://reactome.org/PathwayBrowser/#/R-HSA-5625426 Retrograde IFT TAS Homo sapiens 36080 R-HSA-5626507 https://reactome.org/PathwayBrowser/#/R-HSA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin TAS Homo sapiens 36080 R-HSA-5635841 https://reactome.org/PathwayBrowser/#/R-HSA-5635841 GLI proteins are phosphorylated TAS Homo sapiens 36080 R-HSA-5662473 https://reactome.org/PathwayBrowser/#/R-HSA-5662473 KGPDC decarboxylates 3-dehydro-L-gulonate to L-xylulose TAS Homo sapiens 36080 R-HSA-5666169 https://reactome.org/PathwayBrowser/#/R-HSA-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 TAS Homo sapiens 36080 R-HSA-5667107 https://reactome.org/PathwayBrowser/#/R-HSA-5667107 SIAH1, SIAH2 ubiquitinate SNCAIP TAS Homo sapiens 36080 R-HSA-5667111 https://reactome.org/PathwayBrowser/#/R-HSA-5667111 PARK2 K63-Ubiquitinates SNCAIP TAS Homo sapiens 36080 R-HSA-5668414 https://reactome.org/PathwayBrowser/#/R-HSA-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK TAS Homo sapiens 36080 R-HSA-5668454 https://reactome.org/PathwayBrowser/#/R-HSA-5668454 K63polyUb-cIAP1,2 ubiquitinates TRAF3 TAS Homo sapiens 36080 R-HSA-5668534 https://reactome.org/PathwayBrowser/#/R-HSA-5668534 cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK TAS Homo sapiens 36080 R-HSA-5672329 https://reactome.org/PathwayBrowser/#/R-HSA-5672329 IQGAP1 binds CLIP1 and microtubules TAS Homo sapiens 36080 R-HSA-5672972 https://reactome.org/PathwayBrowser/#/R-HSA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex TAS Homo sapiens 36080 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 36080 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 36080 R-HSA-5672980 https://reactome.org/PathwayBrowser/#/R-HSA-5672980 Dissociation of RAS:RAF complex TAS Homo sapiens 36080 R-HSA-5675470 https://reactome.org/PathwayBrowser/#/R-HSA-5675470 BIRC2/3 (cIAP1/2) is autoubiquitinated TAS Homo sapiens 36080 R-HSA-5686625 https://reactome.org/PathwayBrowser/#/R-HSA-5686625 LAIR1 binds collagen TAS Homo sapiens 36080 R-HSA-5687081 https://reactome.org/PathwayBrowser/#/R-HSA-5687081 MAPK6 is ubiquitinated at the N-terminal TAS Homo sapiens 36080 R-HSA-5688797 https://reactome.org/PathwayBrowser/#/R-HSA-5688797 ATXN3 family cleave Ub chains TAS Homo sapiens 36080 R-HSA-5688837 https://reactome.org/PathwayBrowser/#/R-HSA-5688837 ATXN3 deubiquitinates polyUb-PARK2 TAS Homo sapiens 36080 R-HSA-5689111 https://reactome.org/PathwayBrowser/#/R-HSA-5689111 PARK2 autoubiquitinates TAS Homo sapiens 36080 R-HSA-5689950 https://reactome.org/PathwayBrowser/#/R-HSA-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN TAS Homo sapiens 36080 R-HSA-5689972 https://reactome.org/PathwayBrowser/#/R-HSA-5689972 USP2 deubiquitinates MDM2,MDM4 TAS Homo sapiens 36080 R-HSA-5689973 https://reactome.org/PathwayBrowser/#/R-HSA-5689973 USP10,USP24,USP42 deubiquitinate TP53 TAS Homo sapiens 36080 R-HSA-5690152 https://reactome.org/PathwayBrowser/#/R-HSA-5690152 USP5 cleaves polyubiquitin TAS Homo sapiens 36080 R-HSA-5690159 https://reactome.org/PathwayBrowser/#/R-HSA-5690159 USP21 deubiquitinates RIPK1,DDX58 TAS Homo sapiens 36080 R-HSA-5690196 https://reactome.org/PathwayBrowser/#/R-HSA-5690196 USP8 deubiquitinates RNF128 TAS Homo sapiens 36080 R-HSA-5690517 https://reactome.org/PathwayBrowser/#/R-HSA-5690517 PPT1 hydrolyses palmitoylated proteins TAS Homo sapiens 36080 R-HSA-5690669 https://reactome.org/PathwayBrowser/#/R-HSA-5690669 CD22 binds itself to form homo-oligomers TAS Homo sapiens 36080 R-HSA-5690701 https://reactome.org/PathwayBrowser/#/R-HSA-5690701 SHP1 binds p-CD22 TAS Homo sapiens 36080 R-HSA-5690702 https://reactome.org/PathwayBrowser/#/R-HSA-5690702 LYN phosphorylates CD22 TAS Homo sapiens 36080 R-HSA-5690740 https://reactome.org/PathwayBrowser/#/R-HSA-5690740 CD22 binds B-cell receptor TAS Homo sapiens 36080 R-HSA-5690759 https://reactome.org/PathwayBrowser/#/R-HSA-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 TAS Homo sapiens 36080 R-HSA-5690827 https://reactome.org/PathwayBrowser/#/R-HSA-5690827 TNFAIP3 (A20) ubiquitinates RIPK1 TAS Homo sapiens 36080 R-HSA-5690856 https://reactome.org/PathwayBrowser/#/R-HSA-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 TAS Homo sapiens 36080 R-HSA-5690870 https://reactome.org/PathwayBrowser/#/R-HSA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 TAS Homo sapiens 36080 R-HSA-5691411 https://reactome.org/PathwayBrowser/#/R-HSA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A TAS Homo sapiens 36080 R-HSA-5691431 https://reactome.org/PathwayBrowser/#/R-HSA-5691431 PSMD14 cleaves K63-linked ubiquitin TAS Homo sapiens 36080 R-HSA-5691439 https://reactome.org/PathwayBrowser/#/R-HSA-5691439 BRISC complex deubiquitinates NLRP3 TAS Homo sapiens 36080 R-HSA-5691512 https://reactome.org/PathwayBrowser/#/R-HSA-5691512 APEH hydrolyses NAc-Ser-protein TAS Homo sapiens 36080 R-HSA-5692437 https://reactome.org/PathwayBrowser/#/R-HSA-5692437 ANG binds F-actin TAS Homo sapiens 36080 R-HSA-5693092 https://reactome.org/PathwayBrowser/#/R-HSA-5693092 Unknown deacetylase deacetylates 7K-BACE1(46-501) TAS Homo sapiens 36080 R-HSA-5693108 https://reactome.org/PathwayBrowser/#/R-HSA-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains TAS Homo sapiens 36080 R-HSA-5694409 https://reactome.org/PathwayBrowser/#/R-HSA-5694409 Nucleotide exchange on RAB1 TAS Homo sapiens 36080 R-HSA-5694417 https://reactome.org/PathwayBrowser/#/R-HSA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 TAS Homo sapiens 36080 R-HSA-5694418 https://reactome.org/PathwayBrowser/#/R-HSA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 TAS Homo sapiens 36080 R-HSA-5694428 https://reactome.org/PathwayBrowser/#/R-HSA-5694428 LMAN family proteins bind glycosylated cargo TAS Homo sapiens 36080 R-HSA-5694439 https://reactome.org/PathwayBrowser/#/R-HSA-5694439 COPII coat binds TRAPPCII and RAB1:GDP TAS Homo sapiens 36080 R-HSA-5694441 https://reactome.org/PathwayBrowser/#/R-HSA-5694441 CSNK1D phosphorylates SEC23 TAS Homo sapiens 36080 R-HSA-5694446 https://reactome.org/PathwayBrowser/#/R-HSA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle TAS Homo sapiens 36080 R-HSA-5694522 https://reactome.org/PathwayBrowser/#/R-HSA-5694522 Inner coat assembly and cargo binding TAS Homo sapiens 36080 R-HSA-5694527 https://reactome.org/PathwayBrowser/#/R-HSA-5694527 Loss of SAR1B GTPase TAS Homo sapiens 36080 R-HSA-5696356 https://reactome.org/PathwayBrowser/#/R-HSA-5696356 OSCAR binds collagen and SP-D TAS Homo sapiens 36080 R-HSA-5696357 https://reactome.org/PathwayBrowser/#/R-HSA-5696357 LAIR2 binds collagen TAS Homo sapiens 36080 R-HSA-5696534 https://reactome.org/PathwayBrowser/#/R-HSA-5696534 USP18 deubiquitinates TAK1:TAB1 TAS Homo sapiens 36080 R-HSA-5696547 https://reactome.org/PathwayBrowser/#/R-HSA-5696547 STAMBPL1 is a deubiquitinase TAS Homo sapiens 36080 R-HSA-5696564 https://reactome.org/PathwayBrowser/#/R-HSA-5696564 USP25 deubiquitinates DDX58 TAS Homo sapiens 36080 R-HSA-5696600 https://reactome.org/PathwayBrowser/#/R-HSA-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 TAS Homo sapiens 36080 R-HSA-5696605 https://reactome.org/PathwayBrowser/#/R-HSA-5696605 USP12, USP26 deubiquitinate AR TAS Homo sapiens 36080 R-HSA-5696627 https://reactome.org/PathwayBrowser/#/R-HSA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG TAS Homo sapiens 36080 R-HSA-5696872 https://reactome.org/PathwayBrowser/#/R-HSA-5696872 USP30 deubiquitinates Ub-MOM proteins TAS Homo sapiens 36080 R-HSA-5696914 https://reactome.org/PathwayBrowser/#/R-HSA-5696914 USP28 deubiquitinates CLSPN and MYC TAS Homo sapiens 36080 R-HSA-5696945 https://reactome.org/PathwayBrowser/#/R-HSA-5696945 USP33 deubiquitinates CCP110,ARRB TAS Homo sapiens 36080 R-HSA-5696947 https://reactome.org/PathwayBrowser/#/R-HSA-5696947 USP47 deubiquitinates POLB TAS Homo sapiens 36080 R-HSA-5696958 https://reactome.org/PathwayBrowser/#/R-HSA-5696958 USP44 deubiquitinates CDC20 TAS Homo sapiens 36080 R-HSA-5696968 https://reactome.org/PathwayBrowser/#/R-HSA-5696968 USP20, USP33 deubiquitinate ADRB2 TAS Homo sapiens 36080 R-HSA-5696997 https://reactome.org/PathwayBrowser/#/R-HSA-5696997 USP24 deubiquitinates DDB2 TAS Homo sapiens 36080 R-HSA-5697009 https://reactome.org/PathwayBrowser/#/R-HSA-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 TAS Homo sapiens 36080 R-HSA-6781779 https://reactome.org/PathwayBrowser/#/R-HSA-6781779 USP13 deubiquitinates BECN1,USP10 TAS Homo sapiens 36080 R-HSA-6781814 https://reactome.org/PathwayBrowser/#/R-HSA-6781814 USP19 deubiquitinates RNF123 TAS Homo sapiens 36080 R-HSA-6781897 https://reactome.org/PathwayBrowser/#/R-HSA-6781897 USP11 deubiquitinates NFKBIA TAS Homo sapiens 36080 R-HSA-6782106 https://reactome.org/PathwayBrowser/#/R-HSA-6782106 USP10 deubiquitinates SNX3, CFTR TAS Homo sapiens 36080 R-HSA-6782685 https://reactome.org/PathwayBrowser/#/R-HSA-6782685 EDEM1,3 hydrolyse (GlcNAc)2 (Man)8b to (GlcNAc)2 (Man)5 TAS Homo sapiens 36080 R-HSA-6782820 https://reactome.org/PathwayBrowser/#/R-HSA-6782820 USP17 deubiquitinates SUDS3 TAS Homo sapiens 36080 R-HSA-6783177 https://reactome.org/PathwayBrowser/#/R-HSA-6783177 USP21 deubiquitinates GATA3,IL33 TAS Homo sapiens 36080 R-HSA-6784213 https://reactome.org/PathwayBrowser/#/R-HSA-6784213 Unknown hydroxyproline carrier transports cytosolic HPRO into the mitochondrial matrix TAS Homo sapiens 36080 R-HSA-6784434 https://reactome.org/PathwayBrowser/#/R-HSA-6784434 An unknown carrier transports cytosolic glyoxylate to the peroxisome TAS Homo sapiens 36080 R-HSA-6784436 https://reactome.org/PathwayBrowser/#/R-HSA-6784436 An unknown carrier transports mitochondrial glyoxylate to the cytosol TAS Homo sapiens 36080 R-HSA-6790087 https://reactome.org/PathwayBrowser/#/R-HSA-6790087 HVEM induses BTLA phosphorylation IEA Homo sapiens 36080 R-HSA-6802910 https://reactome.org/PathwayBrowser/#/R-HSA-6802910 Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants TAS Homo sapiens 36080 R-HSA-6802911 https://reactome.org/PathwayBrowser/#/R-HSA-6802911 High kinase activity BRAF complexes phosphorylate MAP2Ks TAS Homo sapiens 36080 R-HSA-6802912 https://reactome.org/PathwayBrowser/#/R-HSA-6802912 High kinase activity BRAF mutants bind MAP2Ks and MAPKs TAS Homo sapiens 36080 R-HSA-6802914 https://reactome.org/PathwayBrowser/#/R-HSA-6802914 RAS:GTP:moderate kinase activity p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 36080 R-HSA-6802918 https://reactome.org/PathwayBrowser/#/R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants TAS Homo sapiens 36080 R-HSA-6802919 https://reactome.org/PathwayBrowser/#/R-HSA-6802919 RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 36080 R-HSA-6802921 https://reactome.org/PathwayBrowser/#/R-HSA-6802921 Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 36080 R-HSA-6802922 https://reactome.org/PathwayBrowser/#/R-HSA-6802922 Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS TAS Homo sapiens 36080 R-HSA-6802925 https://reactome.org/PathwayBrowser/#/R-HSA-6802925 Mutant RAS:p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 36080 R-HSA-6802926 https://reactome.org/PathwayBrowser/#/R-HSA-6802926 Mutant RAS:p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 36080 R-HSA-6802932 https://reactome.org/PathwayBrowser/#/R-HSA-6802932 Dissociation of BRAF/RAF fusion complex TAS Homo sapiens 36080 R-HSA-6802933 https://reactome.org/PathwayBrowser/#/R-HSA-6802933 p-BRAF and RAF fusion dimers phosphorylate MAP2Ks TAS Homo sapiens 36080 R-HSA-6802934 https://reactome.org/PathwayBrowser/#/R-HSA-6802934 p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs TAS Homo sapiens 36080 R-HSA-6802935 https://reactome.org/PathwayBrowser/#/R-HSA-6802935 MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers TAS Homo sapiens 36080 R-HSA-6802942 https://reactome.org/PathwayBrowser/#/R-HSA-6802942 RAS:GTP:p-RAF complexes paradoxically bind MAP2Ks and MAPKs TAS Homo sapiens 36080 R-HSA-6802943 https://reactome.org/PathwayBrowser/#/R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 36080 R-HSA-6803060 https://reactome.org/PathwayBrowser/#/R-HSA-6803060 DCD(63-110) is processed to DCD(63-109) TAS Homo sapiens 36080 R-HSA-6803227 https://reactome.org/PathwayBrowser/#/R-HSA-6803227 Dissociation of high activity BRAF complexes TAS Homo sapiens 36080 R-HSA-6803230 https://reactome.org/PathwayBrowser/#/R-HSA-6803230 Dissociation of moderate activity BRAF complexes TAS Homo sapiens 36080 R-HSA-6803233 https://reactome.org/PathwayBrowser/#/R-HSA-6803233 Dissociation of oncogenic RAS:RAF complex TAS Homo sapiens 36080 R-HSA-6803234 https://reactome.org/PathwayBrowser/#/R-HSA-6803234 Dissociation of paradoxically activated RAS:BRAF complexes TAS Homo sapiens 36080 R-HSA-6806610 https://reactome.org/PathwayBrowser/#/R-HSA-6806610 Keratin filament formation TAS Homo sapiens 36080 R-HSA-6806629 https://reactome.org/PathwayBrowser/#/R-HSA-6806629 Formation of tonofilament bundles TAS Homo sapiens 36080 R-HSA-6809003 https://reactome.org/PathwayBrowser/#/R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin TAS Homo sapiens 36080 R-HSA-6809006 https://reactome.org/PathwayBrowser/#/R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex TAS Homo sapiens 36080 R-HSA-6809393 https://reactome.org/PathwayBrowser/#/R-HSA-6809393 Keratin filaments bind cell-cell adhesion complexes TAS Homo sapiens 36080 R-HSA-6809663 https://reactome.org/PathwayBrowser/#/R-HSA-6809663 Formation of hair keratin fibres TAS Homo sapiens 36080 R-HSA-6810357 https://reactome.org/PathwayBrowser/#/R-HSA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network TAS Homo sapiens 36080 R-HSA-6810937 https://reactome.org/PathwayBrowser/#/R-HSA-6810937 Lamellar bodies bind the early cornified envelope TAS Homo sapiens 36080 R-HSA-6811423 https://reactome.org/PathwayBrowser/#/R-HSA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs TAS Homo sapiens 36080 R-HSA-6811426 https://reactome.org/PathwayBrowser/#/R-HSA-6811426 Retrograde COPI vesicles bind kinesin and microtubules TAS Homo sapiens 36080 R-HSA-6811539 https://reactome.org/PathwayBrowser/#/R-HSA-6811539 Reinforcement of the Cornified Envelope TAS Homo sapiens 36080 R-HSA-6814298 https://reactome.org/PathwayBrowser/#/R-HSA-6814298 Late envelope proteins bind cornified envelope:CDSN TAS Homo sapiens 36080 R-HSA-6814387 https://reactome.org/PathwayBrowser/#/R-HSA-6814387 CASP14 cleaves filaggrin TAS Homo sapiens 36080 R-HSA-6814734 https://reactome.org/PathwayBrowser/#/R-HSA-6814734 CDSN binds the cornified envelope TAS Homo sapiens 36080 R-HSA-6814764 https://reactome.org/PathwayBrowser/#/R-HSA-6814764 Plasma membrane resorption TAS Homo sapiens 36080 R-HSA-688136 https://reactome.org/PathwayBrowser/#/R-HSA-688136 TNFAIP3 (A20) deubiquitinates RIP2 TAS Homo sapiens 36080 R-HSA-688137 https://reactome.org/PathwayBrowser/#/R-HSA-688137 RIP2 is K63 polyubiquitinated TAS Homo sapiens 36080 R-HSA-68914 https://reactome.org/PathwayBrowser/#/R-HSA-68914 DNA polymerase alpha:primase binds at the origin TAS Homo sapiens 36080 R-HSA-68916 https://reactome.org/PathwayBrowser/#/R-HSA-68916 DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin TAS Homo sapiens 36080 R-HSA-68917 https://reactome.org/PathwayBrowser/#/R-HSA-68917 Cdc45 associates with the pre-replicative complex at the origin TAS Homo sapiens 36080 R-HSA-68918 https://reactome.org/PathwayBrowser/#/R-HSA-68918 CDK and DDK associate with the Mcm10:pre-replicative complex TAS Homo sapiens 36080 R-HSA-68960 https://reactome.org/PathwayBrowser/#/R-HSA-68960 DNA polymerase epsilon binds at the origin TAS Homo sapiens 36080 R-HSA-69598 https://reactome.org/PathwayBrowser/#/R-HSA-69598 Ubiquitination of phosphorylated Cdc25A TAS Homo sapiens 36080 R-HSA-69754 https://reactome.org/PathwayBrowser/#/R-HSA-69754 Phosphorylation of proteins involved in G2/M transition by active Cyclin A1:Cdc2 complexes TAS Homo sapiens 36080 R-HSA-69756 https://reactome.org/PathwayBrowser/#/R-HSA-69756 Phosphorylation of proteins involved in G2/M transition by active Cyclin A2:Cdc2 complexes TAS Homo sapiens 36080 R-HSA-70830 https://reactome.org/PathwayBrowser/#/R-HSA-70830 tiglyl-CoA + H2O <=> alpha-methyl-beta-hydroxybutyryl-CoA TAS Homo sapiens 36080 R-HSA-71239 https://reactome.org/PathwayBrowser/#/R-HSA-71239 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ IEA Homo sapiens 36080 R-HSA-72180 https://reactome.org/PathwayBrowser/#/R-HSA-72180 Cleavage of mRNA at the 3'-end TAS Homo sapiens 36080 R-HSA-72619 https://reactome.org/PathwayBrowser/#/R-HSA-72619 eIF2:GTP is hydrolyzed, eIFs are released TAS Homo sapiens 36080 R-HSA-72621 https://reactome.org/PathwayBrowser/#/R-HSA-72621 Ribosomal scanning TAS Homo sapiens 36080 R-HSA-72635 https://reactome.org/PathwayBrowser/#/R-HSA-72635 eIF4F binds to mRNP TAS Homo sapiens 36080 R-HSA-72647 https://reactome.org/PathwayBrowser/#/R-HSA-72647 Cap-bound mRNA is activated by helicases TAS Homo sapiens 36080 R-HSA-72697 https://reactome.org/PathwayBrowser/#/R-HSA-72697 Start codon recognition TAS Homo sapiens 36080 R-HSA-741386 https://reactome.org/PathwayBrowser/#/R-HSA-741386 RIP2 induces K63-linked ubiquitination of NEMO TAS Homo sapiens 36080 R-HSA-741411 https://reactome.org/PathwayBrowser/#/R-HSA-741411 CYLD deubiquitinates NEMO TAS Homo sapiens 36080 R-HSA-74747 https://reactome.org/PathwayBrowser/#/R-HSA-74747 Dephosphorylation of p-Y-IRS1,p-Y-IRS2 TAS Homo sapiens 36080 R-HSA-74748 https://reactome.org/PathwayBrowser/#/R-HSA-74748 De-phosphorylation of p-Y427-SHC1 TAS Homo sapiens 36080 R-HSA-75824 https://reactome.org/PathwayBrowser/#/R-HSA-75824 Ubiquitination of Cyclin D1 TAS Homo sapiens 36080 R-HSA-75851 https://reactome.org/PathwayBrowser/#/R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 36080 R-HSA-76494 https://reactome.org/PathwayBrowser/#/R-HSA-76494 POR reduces CYP450:Fe3+ to CYP450:Fe2+ TAS Homo sapiens 36080 R-HSA-844438 https://reactome.org/PathwayBrowser/#/R-HSA-844438 NLRP1 oligomerizes TAS Homo sapiens 36080 R-HSA-844610 https://reactome.org/PathwayBrowser/#/R-HSA-844610 NLRP3 recruits PYCARD (ASC) via a PYD-PYD interaction TAS Homo sapiens 36080 R-HSA-844612 https://reactome.org/PathwayBrowser/#/R-HSA-844612 PYCARD recruits procaspase-1 via CARD TAS Homo sapiens 36080 R-HSA-844618 https://reactome.org/PathwayBrowser/#/R-HSA-844618 dsDNA:AIM2:ASC cluster binds procaspase-1 IEA Homo sapiens 36080 R-HSA-844620 https://reactome.org/PathwayBrowser/#/R-HSA-844620 dsDNA:AIM2 clusters bind ASC IEA Homo sapiens 36080 R-HSA-847070 https://reactome.org/PathwayBrowser/#/R-HSA-847070 Phosphorylated TAK1 dissociates from the TLR3 receptor complex TAS Homo sapiens 36080 R-HSA-874079 https://reactome.org/PathwayBrowser/#/R-HSA-874079 AIM2 oligomerizes IEA Homo sapiens 36080 R-HSA-879925 https://reactome.org/PathwayBrowser/#/R-HSA-879925 SHC1 bound to the common beta chain becomes tyrosine phosphorylated TAS Homo sapiens 36080 R-HSA-8848658 https://reactome.org/PathwayBrowser/#/R-HSA-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins TAS Homo sapiens 36080 R-HSA-8849157 https://reactome.org/PathwayBrowser/#/R-HSA-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally TAS Homo sapiens 36080 R-HSA-8849350 https://reactome.org/PathwayBrowser/#/R-HSA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex TAS Homo sapiens 36080 R-HSA-8849353 https://reactome.org/PathwayBrowser/#/R-HSA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER TAS Homo sapiens 36080 R-HSA-8850594 https://reactome.org/PathwayBrowser/#/R-HSA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins TAS Homo sapiens 36080 R-HSA-8852200 https://reactome.org/PathwayBrowser/#/R-HSA-8852200 Inactivation of LCK by PTPN22 TAS Homo sapiens 36080 R-HSA-8852266 https://reactome.org/PathwayBrowser/#/R-HSA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s TAS Homo sapiens 36080 R-HSA-8852280 https://reactome.org/PathwayBrowser/#/R-HSA-8852280 GTSE1 binds microtubule lattice in interphase cells TAS Homo sapiens 36080 R-HSA-8852298 https://reactome.org/PathwayBrowser/#/R-HSA-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends TAS Homo sapiens 36080 R-HSA-8852306 https://reactome.org/PathwayBrowser/#/R-HSA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends TAS Homo sapiens 36080 R-HSA-8852481 https://reactome.org/PathwayBrowser/#/R-HSA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates TAS Homo sapiens 36080 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 36080 R-HSA-8855381 https://reactome.org/PathwayBrowser/#/R-HSA-8855381 PTPN22 dephosphorylates ZAP70 TAS Homo sapiens 36080 R-HSA-8862184 https://reactome.org/PathwayBrowser/#/R-HSA-8862184 USP48 cleaves polyubiquitin TAS Homo sapiens 36080 R-HSA-8865774 https://reactome.org/PathwayBrowser/#/R-HSA-8865774 TTLLs polyglutamylate tubulin TAS Homo sapiens 36080 R-HSA-8866105 https://reactome.org/PathwayBrowser/#/R-HSA-8866105 CCPs deglutamylate tubulin IEA Homo sapiens 36080 R-HSA-8867288 https://reactome.org/PathwayBrowser/#/R-HSA-8867288 OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5 TAS Homo sapiens 36080 R-HSA-8867370 https://reactome.org/PathwayBrowser/#/R-HSA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin TAS Homo sapiens 36080 R-HSA-8868230 https://reactome.org/PathwayBrowser/#/R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery TAS Homo sapiens 36080 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 36080 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 36080 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 36080 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 36080 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 36080 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 36080 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 36080 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 36080 R-HSA-8869456 https://reactome.org/PathwayBrowser/#/R-HSA-8869456 USP4 deubiquitinate TRAF2,TRAF6 TAS Homo sapiens 36080 R-HSA-8869506 https://reactome.org/PathwayBrowser/#/R-HSA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 TAS Homo sapiens 36080 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 36080 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 36080 R-HSA-8874079 https://reactome.org/PathwayBrowser/#/R-HSA-8874079 PTK2 binds activated MET TAS Homo sapiens 36080 R-HSA-8874162 https://reactome.org/PathwayBrowser/#/R-HSA-8874162 ATF6B:HSPA5 (ATF6-beta:BiP) dissociates and HSPA5 binds unfolded protein IEA Homo sapiens 36080 R-HSA-8875431 https://reactome.org/PathwayBrowser/#/R-HSA-8875431 LRIG1 undergoes ubiquitination TAS Homo sapiens 36080 R-HSA-8876889 https://reactome.org/PathwayBrowser/#/R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 36080 R-HSA-8942224 https://reactome.org/PathwayBrowser/#/R-HSA-8942224 Filaggrin binds Keratin tonofilament:Desmosome TAS Homo sapiens 36080 R-HSA-8943987 https://reactome.org/PathwayBrowser/#/R-HSA-8943987 SCUBE1, SCUBE3 oligomerize TAS Homo sapiens 36080 R-HSA-8948015 https://reactome.org/PathwayBrowser/#/R-HSA-8948015 hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb TAS Homo sapiens 36080 R-HSA-8948063 https://reactome.org/PathwayBrowser/#/R-HSA-8948063 hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 TAS Homo sapiens 36080 R-HSA-8951499 https://reactome.org/PathwayBrowser/#/R-HSA-8951499 Loading of antigenic peptides on to class I MHC TAS Homo sapiens 36080 R-HSA-8955869 https://reactome.org/PathwayBrowser/#/R-HSA-8955869 Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin IEA Homo sapiens 36080 R-HSA-901006 https://reactome.org/PathwayBrowser/#/R-HSA-901006 Binding of Malectin TAS Homo sapiens 36080 R-HSA-9010190 https://reactome.org/PathwayBrowser/#/R-HSA-9010190 ROBO3 binds NELL2 IEA Homo sapiens 36080 R-HSA-901024 https://reactome.org/PathwayBrowser/#/R-HSA-901024 MAN1B1 hydrolyses 1,2-linked mannose (a branch) TAS Homo sapiens 36080 R-HSA-901036 https://reactome.org/PathwayBrowser/#/R-HSA-901036 MAN1B1 hydrolyses a second 1,2-linked mannose (a branch) TAS Homo sapiens 36080 R-HSA-901039 https://reactome.org/PathwayBrowser/#/R-HSA-901039 MAN1B1 hydrolyses 1,2-linked mannose (c branch) TAS Homo sapiens 36080 R-HSA-901047 https://reactome.org/PathwayBrowser/#/R-HSA-901047 Binding of ERp57 TAS Homo sapiens 36080 R-HSA-901074 https://reactome.org/PathwayBrowser/#/R-HSA-901074 MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch) TAS Homo sapiens 36080 R-HSA-9012761 https://reactome.org/PathwayBrowser/#/R-HSA-9012761 The p75NTR:NgR:MDGI binds RHOA-GDI TAS Homo sapiens 36080 R-HSA-9014342 https://reactome.org/PathwayBrowser/#/R-HSA-9014342 K63-linked ubiquitination of RIP1 bound to the activated TLR complex TAS Homo sapiens 36080 R-HSA-9014652 https://reactome.org/PathwayBrowser/#/R-HSA-9014652 Translation of ROBO3.2 mRNA is negatively regulated by NMD IEA Homo sapiens 36080 R-HSA-9018867 https://reactome.org/PathwayBrowser/#/R-HSA-9018867 5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2 TAS Homo sapiens 36080 R-HSA-9018874 https://reactome.org/PathwayBrowser/#/R-HSA-9018874 CYP monooxygenates EPA to 18(S)-HpEPE TAS Homo sapiens 36080 R-HSA-9018901 https://reactome.org/PathwayBrowser/#/R-HSA-9018901 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HpEPE to 18(R)-RvE2 TAS Homo sapiens 36080 R-HSA-9020249 https://reactome.org/PathwayBrowser/#/R-HSA-9020249 Hydroperoxy reductase reduces 4(S)-Hp-17(S)-HDHA to RvD6 TAS Homo sapiens 36080 R-HSA-9020260 https://reactome.org/PathwayBrowser/#/R-HSA-9020260 Hydroperoxy reducatse reduces 7(S)-Hp-17(S)-HDHA to RvD5 TAS Homo sapiens 36080 R-HSA-9021050 https://reactome.org/PathwayBrowser/#/R-HSA-9021050 HSBP1 oligomer binds ESRs TAS Homo sapiens 36080 R-HSA-9021072 https://reactome.org/PathwayBrowser/#/R-HSA-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 TAS Homo sapiens 36080 R-HSA-9021306 https://reactome.org/PathwayBrowser/#/R-HSA-9021306 C1-Inh binds and inactivates C1r, C1s TAS Homo sapiens 36080 R-HSA-9024624 https://reactome.org/PathwayBrowser/#/R-HSA-9024624 Hydroperoxy reductase reduces 4(S)-Hp-17(R)-HDHA to AT-RvD6 TAS Homo sapiens 36080 R-HSA-9024630 https://reactome.org/PathwayBrowser/#/R-HSA-9024630 Hydroperoxy reductase reduces 7(S)-Hp-17(R)-HDHA to AT-RvD5 TAS Homo sapiens 36080 R-HSA-9024973 https://reactome.org/PathwayBrowser/#/R-HSA-9024973 Epoxide hydrolase hydrolyses 13(S),14(S)-epoxy-DHA to MaR1 TAS Homo sapiens 36080 R-HSA-9025007 https://reactome.org/PathwayBrowser/#/R-HSA-9025007 Hydroperoxy reductase reduces 7(S),14(S)-diHp-DHA to 7-epi-MaR1 TAS Homo sapiens 36080 R-HSA-9025998 https://reactome.org/PathwayBrowser/#/R-HSA-9025998 Epoxide hydrolase hydrolyses 13,14-epoxy-DPAn-3 to MaR1n-3 DPA or MaR2n-3 DPA TAS Homo sapiens 36080 R-HSA-9026000 https://reactome.org/PathwayBrowser/#/R-HSA-9026000 Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA TAS Homo sapiens 36080 R-HSA-9026001 https://reactome.org/PathwayBrowser/#/R-HSA-9026001 Hydroperoxy reductase reduces 7,17-diHp-DPAn-3 to RvD5n-3DPA TAS Homo sapiens 36080 R-HSA-9026008 https://reactome.org/PathwayBrowser/#/R-HSA-9026008 Epoxide hydrolase hydrolyses 7,8-epoxy-HDPAn-3 to RvD1n-3DPA or RvD2n-3DPA TAS Homo sapiens 36080 R-HSA-9026757 https://reactome.org/PathwayBrowser/#/R-HSA-9026757 GGT hydrolyses MCTR1 to MCTR2 TAS Homo sapiens 36080 R-HSA-9026771 https://reactome.org/PathwayBrowser/#/R-HSA-9026771 DPEP hydrolyses MCTR2 to MCTR3 TAS Homo sapiens 36080 R-HSA-9026901 https://reactome.org/PathwayBrowser/#/R-HSA-9026901 GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1 TAS Homo sapiens 36080 R-HSA-9026907 https://reactome.org/PathwayBrowser/#/R-HSA-9026907 GGT hydrolyses PCTR2 to PCTR3 TAS Homo sapiens 36080 R-HSA-9026912 https://reactome.org/PathwayBrowser/#/R-HSA-9026912 GGT hydrolyses PCTR1 to PCTR2 TAS Homo sapiens 36080 R-HSA-9026916 https://reactome.org/PathwayBrowser/#/R-HSA-9026916 GGT hydrolyses RCTR2 to RCTR3 TAS Homo sapiens 36080 R-HSA-9026917 https://reactome.org/PathwayBrowser/#/R-HSA-9026917 Lipoxygenase dehydrogenates 7(S),17(S)-diHp-DHA to 7S(8)-epoxy-17(S)-HDHA TAS Homo sapiens 36080 R-HSA-9026918 https://reactome.org/PathwayBrowser/#/R-HSA-9026918 Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA TAS Homo sapiens 36080 R-HSA-9026927 https://reactome.org/PathwayBrowser/#/R-HSA-9026927 GGT hydrolyses RCTR1 to RCTR2 TAS Homo sapiens 36080 R-HSA-9027033 https://reactome.org/PathwayBrowser/#/R-HSA-9027033 Hydroperoxy reducatase reduces 14(S)-Hp-DHA to 14(S)-HDHA TAS Homo sapiens 36080 R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 36080 R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 36080 R-HSA-9027531 https://reactome.org/PathwayBrowser/#/R-HSA-9027531 Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA TAS Homo sapiens 36080 R-HSA-9027562 https://reactome.org/PathwayBrowser/#/R-HSA-9027562 Dehydrogenase dehydrogenates 17-HDHA to 17-oxo-DHA TAS Homo sapiens 36080 R-HSA-9027598 https://reactome.org/PathwayBrowser/#/R-HSA-9027598 Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3 TAS Homo sapiens 36080 R-HSA-9027600 https://reactome.org/PathwayBrowser/#/R-HSA-9027600 Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3 TAS Homo sapiens 36080 R-HSA-9027625 https://reactome.org/PathwayBrowser/#/R-HSA-9027625 5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3 TAS Homo sapiens 36080 R-HSA-9027631 https://reactome.org/PathwayBrowser/#/R-HSA-9027631 5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA TAS Homo sapiens 36080 R-HSA-9027632 https://reactome.org/PathwayBrowser/#/R-HSA-9027632 5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA TAS Homo sapiens 36080 R-HSA-9027670 https://reactome.org/PathwayBrowser/#/R-HSA-9027670 ESTG binding induces ESR depalmitoylation TAS Homo sapiens 36080 R-HSA-9036008 https://reactome.org/PathwayBrowser/#/R-HSA-9036008 Defective MAN1B1 does not hydrolyse a second 1,2-linked mannose (a branch) TAS Homo sapiens 36080 R-HSA-9036011 https://reactome.org/PathwayBrowser/#/R-HSA-9036011 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (b branch) TAS Homo sapiens 36080 R-HSA-9036012 https://reactome.org/PathwayBrowser/#/R-HSA-9036012 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (c branch) TAS Homo sapiens 36080 R-HSA-912291 https://reactome.org/PathwayBrowser/#/R-HSA-912291 Incorrectly folded glycoproteins translocate to the ERQC TAS Homo sapiens 36080 R-HSA-912627 https://reactome.org/PathwayBrowser/#/R-HSA-912627 CBL ubiquitinates PI3K TAS Homo sapiens 36080 R-HSA-915148 https://reactome.org/PathwayBrowser/#/R-HSA-915148 Correctly folded glycoproteins translocate to the Golgi TAS Homo sapiens 36080 R-HSA-918224 https://reactome.org/PathwayBrowser/#/R-HSA-918224 DDX58 is K63 polyubiquitinated TAS Homo sapiens 36080 R-HSA-936381 https://reactome.org/PathwayBrowser/#/R-HSA-936381 OTUD5 deubiquitinates TRAF3 TAS Homo sapiens 36080 R-HSA-936462 https://reactome.org/PathwayBrowser/#/R-HSA-936462 PIN1 mediated IRF3 degradation TAS Homo sapiens 36080 R-HSA-936475 https://reactome.org/PathwayBrowser/#/R-HSA-936475 Negative regulation of DDX58/IFIH1 signaling by RNF216 TAS Homo sapiens 36080 R-HSA-936947 https://reactome.org/PathwayBrowser/#/R-HSA-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex TAS Homo sapiens 36080 R-HSA-936951 https://reactome.org/PathwayBrowser/#/R-HSA-936951 Activation of TAK1 complex bound to activated TLR4 complex TAS Homo sapiens 36080 R-HSA-936960 https://reactome.org/PathwayBrowser/#/R-HSA-936960 Activated TRAF6:p-IRAK2 interacts with TAK1 complex TAS Homo sapiens 36080 R-HSA-936986 https://reactome.org/PathwayBrowser/#/R-HSA-936986 Activated TRAF6 synthesizes unanchored polyubiquitin chains TAS Homo sapiens 36080 R-HSA-936991 https://reactome.org/PathwayBrowser/#/R-HSA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 TAS Homo sapiens 36080 R-HSA-937050 https://reactome.org/PathwayBrowser/#/R-HSA-937050 Pellino ubiquitinates hp-IRAK1 TAS Homo sapiens 36080 R-HSA-937075 https://reactome.org/PathwayBrowser/#/R-HSA-937075 Phosphorylated TAK1 leaves activated TLR receptor complex TAS Homo sapiens 36080 R-HSA-947991 https://reactome.org/PathwayBrowser/#/R-HSA-947991 Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi TAS Homo sapiens 36080 R-HSA-9603534 https://reactome.org/PathwayBrowser/#/R-HSA-9603534 Unknown caspase cleaves NTRK3 IEA Homo sapiens 36080 R-HSA-9604606 https://reactome.org/PathwayBrowser/#/R-HSA-9604606 Unknown kinase phosphorylates NICD4 IEA Homo sapiens 36080 R-HSA-9606151 https://reactome.org/PathwayBrowser/#/R-HSA-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 TAS Homo sapiens 36080 R-HSA-9606159 https://reactome.org/PathwayBrowser/#/R-HSA-9606159 BTK autophosphorylates IEA Homo sapiens 36080 R-HSA-9606162 https://reactome.org/PathwayBrowser/#/R-HSA-9606162 Phosphorylated BTK phosphorylates PLCG2 IEA Homo sapiens 36080 R-HSA-9606163 https://reactome.org/PathwayBrowser/#/R-HSA-9606163 p-SYK and LYN phosphorylate BTK IEA Homo sapiens 36080 R-HSA-9610408 https://reactome.org/PathwayBrowser/#/R-HSA-9610408 GluN1:GluN2B (GRIN1:GRIN2B) di-heterotetramers bind LIN7:CASK:APBA1, DLG1 and KIF17 IEA Homo sapiens 36080 R-HSA-9610627 https://reactome.org/PathwayBrowser/#/R-HSA-9610627 KIF17 transports GluN1:GluN2B (GRIN1:GRIN2B) NMDA receptors to the plasma membrane IEA Homo sapiens 36080 R-HSA-9614343 https://reactome.org/PathwayBrowser/#/R-HSA-9614343 Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs TAS Homo sapiens 36080 R-HSA-9614367 https://reactome.org/PathwayBrowser/#/R-HSA-9614367 HCMV Nuclear Pore Docking TAS Homo sapiens 36080 R-HSA-9615721 https://reactome.org/PathwayBrowser/#/R-HSA-9615721 HSPA8 binds substrate IEA Homo sapiens 36080 R-HSA-9619542 https://reactome.org/PathwayBrowser/#/R-HSA-9619542 AMPK negatively regulates binding of MAPT to microtubules IEA Homo sapiens 36080 R-HSA-9620197 https://reactome.org/PathwayBrowser/#/R-HSA-9620197 HSPA8:Substrate binds LAMP2a IEA Homo sapiens 36080 R-HSA-9622831 https://reactome.org/PathwayBrowser/#/R-HSA-9622831 Substrate:LAMP2a binds HSP90 IEA Homo sapiens 36080 R-HSA-9622840 https://reactome.org/PathwayBrowser/#/R-HSA-9622840 HSPA8 dissociates from LAMP2A-bound substrate IEA Homo sapiens 36080 R-HSA-9624014 https://reactome.org/PathwayBrowser/#/R-HSA-9624014 SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 TAS Homo sapiens 36080 R-HSA-9624017 https://reactome.org/PathwayBrowser/#/R-HSA-9624017 p-SHC1 binds integrin alpha5beta1:fibronectin TAS Homo sapiens 36080 R-HSA-9624158 https://reactome.org/PathwayBrowser/#/R-HSA-9624158 Substrate:LAMP2a:HSP90 polymerizes IEA Homo sapiens 36080 R-HSA-9625188 https://reactome.org/PathwayBrowser/#/R-HSA-9625188 HSPA8 transports unfolded substrate to lysosomal lumen for degradation IEA Homo sapiens 36080 R-HSA-9625196 https://reactome.org/PathwayBrowser/#/R-HSA-9625196 Unfolded substrate in LAMP2a multimeric complex binds HSPA8 IEA Homo sapiens 36080 R-HSA-9625197 https://reactome.org/PathwayBrowser/#/R-HSA-9625197 GFAP binds LAMP2a multimer IEA Homo sapiens 36080 R-HSA-9626039 https://reactome.org/PathwayBrowser/#/R-HSA-9626039 pGFAP binds GFAP in LAMP2a multimer IEA Homo sapiens 36080 R-HSA-9626060 https://reactome.org/PathwayBrowser/#/R-HSA-9626060 HSPA8:Substrate dissociates from LAMP2a multimer IEA Homo sapiens 36080 R-HSA-9626242 https://reactome.org/PathwayBrowser/#/R-HSA-9626242 p-GFAP:GFAP dissociates from LAMP2a multimer IEA Homo sapiens 36080 R-HSA-9626253 https://reactome.org/PathwayBrowser/#/R-HSA-9626253 HSPA8 binds LAMP2a multimers IEA Homo sapiens 36080 R-HSA-9626256 https://reactome.org/PathwayBrowser/#/R-HSA-9626256 HSPA8:LAMP2a multimers depolymerizes to monomers IEA Homo sapiens 36080 R-HSA-9628444 https://reactome.org/PathwayBrowser/#/R-HSA-9628444 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation TAS Homo sapiens 36080 R-HSA-9631065 https://reactome.org/PathwayBrowser/#/R-HSA-9631065 Substrate translocates into late endosomal lumen IEA Homo sapiens 36080 R-HSA-9631068 https://reactome.org/PathwayBrowser/#/R-HSA-9631068 HSPA8:substrate binds late endosomal phospholipids IEA Homo sapiens 36080 R-HSA-9645394 https://reactome.org/PathwayBrowser/#/R-HSA-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation TAS Homo sapiens 36080 R-HSA-9645406 https://reactome.org/PathwayBrowser/#/R-HSA-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) TAS Homo sapiens 36080 R-HSA-9645442 https://reactome.org/PathwayBrowser/#/R-HSA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex TAS Homo sapiens 36080 R-HSA-9646383 https://reactome.org/PathwayBrowser/#/R-HSA-9646383 Dynein motors transport misfolded proteins IEA Homo sapiens 36080 R-HSA-9646390 https://reactome.org/PathwayBrowser/#/R-HSA-9646390 Misfolded proteins:HDAC6:Dynein motor binds microtubule IEA Homo sapiens 36080 R-HSA-9646679 https://reactome.org/PathwayBrowser/#/R-HSA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome TAS Homo sapiens 36080 R-HSA-9646685 https://reactome.org/PathwayBrowser/#/R-HSA-9646685 Aggresome dissociates from dynein and microtubule TAS Homo sapiens 36080 R-HSA-9648017 https://reactome.org/PathwayBrowser/#/R-HSA-9648017 EML4 binds to microtubules TAS Homo sapiens 36080 R-HSA-9648114 https://reactome.org/PathwayBrowser/#/R-HSA-9648114 EML4 recruits NUDC to mitotic spindle TAS Homo sapiens 36080 R-HSA-9653514 https://reactome.org/PathwayBrowser/#/R-HSA-9653514 USP17L2 deubiquitinates RCE1 TAS Homo sapiens 36080 R-HSA-9656209 https://reactome.org/PathwayBrowser/#/R-HSA-9656209 Dissociation of RAS:RAF1 mutant complex TAS Homo sapiens 36080 R-HSA-9656211 https://reactome.org/PathwayBrowser/#/R-HSA-9656211 MAP2Ks and MAPKs bind to the activated mutant RAF1 complex TAS Homo sapiens 36080 R-HSA-9656214 https://reactome.org/PathwayBrowser/#/R-HSA-9656214 MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants TAS Homo sapiens 36080 R-HSA-9656215 https://reactome.org/PathwayBrowser/#/R-HSA-9656215 RAF1 mutant complexes phosphorylate MAP2K dimer TAS Homo sapiens 36080 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 36080 R-HSA-9657603 https://reactome.org/PathwayBrowser/#/R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs TAS Homo sapiens 36080 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 36080 R-HSA-9657608 https://reactome.org/PathwayBrowser/#/R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK TAS Homo sapiens 36080 R-HSA-9659380 https://reactome.org/PathwayBrowser/#/R-HSA-9659380 Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell IEA Homo sapiens 36080 R-HSA-9661446 https://reactome.org/PathwayBrowser/#/R-HSA-9661446 BMG, BDG translocates from ER lumen to cytosol TAS Homo sapiens 36080 R-HSA-9661710 https://reactome.org/PathwayBrowser/#/R-HSA-9661710 An unknown oxidase oxidises D-UBGN to UBN TAS Homo sapiens 36080 R-HSA-9661726 https://reactome.org/PathwayBrowser/#/R-HSA-9661726 An unknown reductase reduces D-UBGN to STBN TAS Homo sapiens 36080 R-HSA-9661745 https://reactome.org/PathwayBrowser/#/R-HSA-9661745 An unknown BILR reduces BIL to D-UBGN TAS Homo sapiens 36080 R-HSA-9663363 https://reactome.org/PathwayBrowser/#/R-HSA-9663363 Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell IEA Homo sapiens 36080 R-HSA-9664278 https://reactome.org/PathwayBrowser/#/R-HSA-9664278 Phosphorylation and activation of PLCG due to FCGR3A effect TAS Homo sapiens 36080 R-HSA-9666458 https://reactome.org/PathwayBrowser/#/R-HSA-9666458 IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole TAS Homo sapiens 36080 R-HSA-9668419 https://reactome.org/PathwayBrowser/#/R-HSA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites TAS Homo sapiens 36080 R-HSA-9673346 https://reactome.org/PathwayBrowser/#/R-HSA-9673346 Unknown kinase phosphorylates p-DVL IEA Homo sapiens 36080 R-HSA-9685195 https://reactome.org/PathwayBrowser/#/R-HSA-9685195 SARS-CoV-1 9b recruits ITCH to MAVS TAS Homo sapiens 36080 R-HSA-9686336 https://reactome.org/PathwayBrowser/#/R-HSA-9686336 SARS-CoV-1 3a oligomerizes TAS Homo sapiens 36080 R-HSA-9686338 https://reactome.org/PathwayBrowser/#/R-HSA-9686338 SARS-CoV-1 3a binds the lysosomal membrane TAS Homo sapiens 36080 R-HSA-9686345 https://reactome.org/PathwayBrowser/#/R-HSA-9686345 SARS-CoV-1 3a binds RIPK1:RIPK3 oligomer TAS Homo sapiens 36080 R-HSA-9686920 https://reactome.org/PathwayBrowser/#/R-HSA-9686920 PELI1 ubiquitinates RIPK3 at K363 TAS Homo sapiens 36080 R-HSA-9687625 https://reactome.org/PathwayBrowser/#/R-HSA-9687625 ATP binds MLKL TAS Homo sapiens 36080 R-HSA-9687638 https://reactome.org/PathwayBrowser/#/R-HSA-9687638 MLKL binds IP4, IP5 and IP6 TAS Homo sapiens 36080 R-HSA-9688456 https://reactome.org/PathwayBrowser/#/R-HSA-9688456 MLKL binds FLOT1, FLOT2 TAS Homo sapiens 36080 R-HSA-9688832 https://reactome.org/PathwayBrowser/#/R-HSA-9688832 MLKL binds PDCD6IP and SDCBP TAS Homo sapiens 36080 R-HSA-9691421 https://reactome.org/PathwayBrowser/#/R-HSA-9691421 BTK binds BTK inhibitors TAS Homo sapiens 36080 R-HSA-9693722 https://reactome.org/PathwayBrowser/#/R-HSA-9693722 Unknown sepiapterin synthase transforms PTHP to sepiapterin TAS Homo sapiens 36080 R-HSA-9701055 https://reactome.org/PathwayBrowser/#/R-HSA-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol TAS Homo sapiens 36080 R-HSA-9701141 https://reactome.org/PathwayBrowser/#/R-HSA-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol TAS Homo sapiens 36080 R-HSA-9724745 https://reactome.org/PathwayBrowser/#/R-HSA-9724745 PLG(20-810) binds aprotinin TAS Homo sapiens 36080 R-HSA-9724753 https://reactome.org/PathwayBrowser/#/R-HSA-9724753 PLG(20-810) binds anti-fibrinolytics TAS Homo sapiens 36080 R-HSA-9729300 https://reactome.org/PathwayBrowser/#/R-HSA-9729300 Unknown kinase phosphorylates nucleoprotein TAS Homo sapiens 36080 R-HSA-975097 https://reactome.org/PathwayBrowser/#/R-HSA-975097 Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation TAS Homo sapiens 36080 R-HSA-975103 https://reactome.org/PathwayBrowser/#/R-HSA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation TAS Homo sapiens 36080 R-HSA-975118 https://reactome.org/PathwayBrowser/#/R-HSA-975118 TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex TAS Homo sapiens 36080 R-HSA-975122 https://reactome.org/PathwayBrowser/#/R-HSA-975122 Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
TAS Homo sapiens 36080 R-HSA-9753916 https://reactome.org/PathwayBrowser/#/R-HSA-9753916 NAPQI binds proteins in hepatocytes TAS Homo sapiens 36080 R-HSA-9754978 https://reactome.org/PathwayBrowser/#/R-HSA-9754978 Unknown kinase phosphorylates RBV-MP TAS Homo sapiens 36080 R-HSA-9758486 https://reactome.org/PathwayBrowser/#/R-HSA-9758486 Unknown kinase phosphorylates 9b TAS Homo sapiens 36080 R-HSA-9758604 https://reactome.org/PathwayBrowser/#/R-HSA-9758604 Ubiquitination of IKBKG by TRAF6 TAS Homo sapiens 36080 R-HSA-9762209 https://reactome.org/PathwayBrowser/#/R-HSA-9762209 BACH1 is phosphorylated at tyrosine 483 TAS Homo sapiens 36080 R-HSA-9766532 https://reactome.org/PathwayBrowser/#/R-HSA-9766532 SQSTM1 oligomer is phosphorylated TAS Homo sapiens 36080 R-HSA-976734 https://reactome.org/PathwayBrowser/#/R-HSA-976734 Amyloid fibrils have additional components TAS Homo sapiens 36080 R-HSA-977136 https://reactome.org/PathwayBrowser/#/R-HSA-977136 Amyloid precursor proteins form ordered fibrils TAS Homo sapiens 36080 R-HSA-9793444 https://reactome.org/PathwayBrowser/#/R-HSA-9793444 ITCH polyubiquitinates MLKL at K50 TAS Homo sapiens 36080 R-HSA-9793451 https://reactome.org/PathwayBrowser/#/R-HSA-9793451 MLKL binds ITCH TAS Homo sapiens 36080 R-HSA-981621 https://reactome.org/PathwayBrowser/#/R-HSA-981621 C3 convertases spontaneously dissociate TAS Homo sapiens 36080 R-HSA-9822532 https://reactome.org/PathwayBrowser/#/R-HSA-9822532 ADAMTS13 cleaves VWF multimer TAS Homo sapiens 36080 R-HSA-9822539 https://reactome.org/PathwayBrowser/#/R-HSA-9822539 VWF multimer binds to collagen type I TAS Homo sapiens 36080 R-HSA-9822734 https://reactome.org/PathwayBrowser/#/R-HSA-9822734 Caplacizumab binds VWF TAS Homo sapiens 36080 R-HSA-9823065 https://reactome.org/PathwayBrowser/#/R-HSA-9823065 GPIb:IX:V binds to VWF multimer:collagen TAS Homo sapiens 36080 R-HSA-9823593 https://reactome.org/PathwayBrowser/#/R-HSA-9823593 VWF variant does not bind to collagen type I TAS Homo sapiens 36080 R-HSA-9823706 https://reactome.org/PathwayBrowser/#/R-HSA-9823706 VWF variant does not bind GPIb:IX:V TAS Homo sapiens 36080 R-HSA-9824402 https://reactome.org/PathwayBrowser/#/R-HSA-9824402 ADAMTS13 variant does not cleave VWF multimer TAS Homo sapiens 36080 R-HSA-982765 https://reactome.org/PathwayBrowser/#/R-HSA-982765 Growth hormone forms dimers and oligomers TAS Homo sapiens 36080 R-HSA-9831136 https://reactome.org/PathwayBrowser/#/R-HSA-9831136 SH pentamer is phosphorylated TAS Homo sapiens 36080 R-HSA-983138 https://reactome.org/PathwayBrowser/#/R-HSA-983138 Transport of MHC heterotrimer to ER exit site TAS Homo sapiens 36080 R-HSA-983142 https://reactome.org/PathwayBrowser/#/R-HSA-983142 Formation of peptide loading complex (PLC) TAS Homo sapiens 36080 R-HSA-983161 https://reactome.org/PathwayBrowser/#/R-HSA-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex TAS Homo sapiens 36080 R-HSA-983259 https://reactome.org/PathwayBrowser/#/R-HSA-983259 Kinesins move along microtubules consuming ATP TAS Homo sapiens 36080 R-HSA-983266 https://reactome.org/PathwayBrowser/#/R-HSA-983266 Kinesins bind microtubules TAS Homo sapiens 36080 R-HSA-9832782 https://reactome.org/PathwayBrowser/#/R-HSA-9832782 p-S232-S237-P is further phosphorylated TAS Homo sapiens 36080 R-HSA-983427 https://reactome.org/PathwayBrowser/#/R-HSA-983427 Expression of peptide bound class I MHC on cell surface TAS Homo sapiens 36080 R-HSA-9834809 https://reactome.org/PathwayBrowser/#/R-HSA-9834809 SUMOylation of PKR TAS Homo sapiens 36080 R-HSA-9836404 https://reactome.org/PathwayBrowser/#/R-HSA-9836404 p-PKR dimer phosphorylates MAPT TAS Homo sapiens 36080 R-HSA-983696 https://reactome.org/PathwayBrowser/#/R-HSA-983696 The Immunoglobulin of the BCR binds antigen TAS Homo sapiens 36080 R-HSA-983700 https://reactome.org/PathwayBrowser/#/R-HSA-983700 SYK binds the activated BCR TAS Homo sapiens 36080 R-HSA-983703 https://reactome.org/PathwayBrowser/#/R-HSA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) TAS Homo sapiens 36080 R-HSA-983707 https://reactome.org/PathwayBrowser/#/R-HSA-983707 SYK autophosphorylates at the activated BCR TAS Homo sapiens 36080 R-HSA-983709 https://reactome.org/PathwayBrowser/#/R-HSA-983709 LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) IEA Homo sapiens 36080 R-HSA-9844241 https://reactome.org/PathwayBrowser/#/R-HSA-9844241 ADAMTS13 cleaves VWF variant multimer TAS Homo sapiens 36080 R-HSA-9844251 https://reactome.org/PathwayBrowser/#/R-HSA-9844251 GP1BA variant binds to VWF multimer:collagen TAS Homo sapiens 36080 R-HSA-990526 https://reactome.org/PathwayBrowser/#/R-HSA-990526 Recruitment of ITCH and K48 ubiquitination of MAVS TAS Homo sapiens 36080 R-HSA-994169 https://reactome.org/PathwayBrowser/#/R-HSA-994169 F-actin capping protein binds to the barbed end of elongating F-actin IEA Homo sapiens 36080 R-HSA-997381 https://reactome.org/PathwayBrowser/#/R-HSA-997381 TDPK phosphorylates ThDP to ThTP TAS Homo sapiens 36080 R-MMU-1022127 https://reactome.org/PathwayBrowser/#/R-MMU-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Mus musculus 36080 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus 36080 R-MMU-1236964 https://reactome.org/PathwayBrowser/#/R-MMU-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Mus musculus 36080 R-MMU-1236965 https://reactome.org/PathwayBrowser/#/R-MMU-1236965 Export of peptide loaded MHC class I complex to PM IEA Mus musculus 36080 R-MMU-140851 https://reactome.org/PathwayBrowser/#/R-MMU-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Mus musculus 36080 R-MMU-158744 https://reactome.org/PathwayBrowser/#/R-MMU-158744 crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin IEA Mus musculus 36080 R-MMU-158747 https://reactome.org/PathwayBrowser/#/R-MMU-158747 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) IEA Mus musculus 36080 R-MMU-158750 https://reactome.org/PathwayBrowser/#/R-MMU-158750 crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin IEA Mus musculus 36080 R-MMU-158756 https://reactome.org/PathwayBrowser/#/R-MMU-158756 crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen IEA Mus musculus 36080 R-MMU-158766 https://reactome.org/PathwayBrowser/#/R-MMU-158766 fibrin multimer, crosslinked -> fibrin digestion products (plasmin) IEA Mus musculus 36080 R-MMU-158781 https://reactome.org/PathwayBrowser/#/R-MMU-158781 crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) IEA Mus musculus 36080 R-MMU-158784 https://reactome.org/PathwayBrowser/#/R-MMU-158784 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen IEA Mus musculus 36080 R-MMU-158795 https://reactome.org/PathwayBrowser/#/R-MMU-158795 fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 IEA Mus musculus 36080 R-MMU-158800 https://reactome.org/PathwayBrowser/#/R-MMU-158800 fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 IEA Mus musculus 36080 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus 36080 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus 36080 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus 36080 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus 36080 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus 36080 R-MMU-198955 https://reactome.org/PathwayBrowser/#/R-MMU-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Mus musculus 36080 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus 36080 R-MMU-199518 https://reactome.org/PathwayBrowser/#/R-MMU-199518 C3d-complexed antigen binds to complement receptor IEA Mus musculus 36080 R-MMU-202165 https://reactome.org/PathwayBrowser/#/R-MMU-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Mus musculus 36080 R-MMU-202168 https://reactome.org/PathwayBrowser/#/R-MMU-202168 Phosphorylation of ZAP-70 by Lck IEA Mus musculus 36080 R-MMU-202174 https://reactome.org/PathwayBrowser/#/R-MMU-202174 Activation of ZAP-70 IEA Mus musculus 36080 R-MMU-202214 https://reactome.org/PathwayBrowser/#/R-MMU-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Mus musculus 36080 R-MMU-202216 https://reactome.org/PathwayBrowser/#/R-MMU-202216 Phosphorylation of SLP-76 IEA Mus musculus 36080 R-MMU-202233 https://reactome.org/PathwayBrowser/#/R-MMU-202233 Inactivation of Lck by Csk IEA Mus musculus 36080 R-MMU-202245 https://reactome.org/PathwayBrowser/#/R-MMU-202245 Phosphorylation of TBSMs in LAT IEA Mus musculus 36080 R-MMU-202248 https://reactome.org/PathwayBrowser/#/R-MMU-202248 Phosphorylation of PLC-gamma1 IEA Mus musculus 36080 R-MMU-202291 https://reactome.org/PathwayBrowser/#/R-MMU-202291 Activation of Lck IEA Mus musculus 36080 R-MMU-202307 https://reactome.org/PathwayBrowser/#/R-MMU-202307 Change of PKC theta conformation IEA Mus musculus 36080 R-MMU-202344 https://reactome.org/PathwayBrowser/#/R-MMU-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Mus musculus 36080 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus 36080 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus 36080 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 36080 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus 36080 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus 36080 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus 36080 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus 36080 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus 36080 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus 36080 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus 36080 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus 36080 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus 36080 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus 36080 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus 36080 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus 36080 R-MMU-2213240 https://reactome.org/PathwayBrowser/#/R-MMU-2213240 Reduction of disulphide bonds in MHC II antigens IEA Mus musculus 36080 R-MMU-2529015 https://reactome.org/PathwayBrowser/#/R-MMU-2529015 Dephosphorylation of CK2-modified condensin I IEA Mus musculus 36080 R-MMU-389758 https://reactome.org/PathwayBrowser/#/R-MMU-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Mus musculus 36080 R-MMU-5690517 https://reactome.org/PathwayBrowser/#/R-MMU-5690517 PPT1 hydrolyses palmitoylated proteins IEA Mus musculus 36080 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus 36080 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus 36080 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus 36080 R-MMU-5691512 https://reactome.org/PathwayBrowser/#/R-MMU-5691512 APEH hydrolyses NAc-Ser-protein IEA Mus musculus 36080 R-MMU-573384 https://reactome.org/PathwayBrowser/#/R-MMU-573384 Transcription of intergenic spacer of the rRNA gene TAS Mus musculus 36080 R-MMU-72619 https://reactome.org/PathwayBrowser/#/R-MMU-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Mus musculus 36080 R-MMU-72621 https://reactome.org/PathwayBrowser/#/R-MMU-72621 Ribosomal scanning IEA Mus musculus 36080 R-MMU-72647 https://reactome.org/PathwayBrowser/#/R-MMU-72647 Cap-bound mRNA is activated by helicases IEA Mus musculus 36080 R-MMU-72697 https://reactome.org/PathwayBrowser/#/R-MMU-72697 Start codon recognition IEA Mus musculus 36080 R-MMU-73747 https://reactome.org/PathwayBrowser/#/R-MMU-73747 Assembly of RNA Polymerase I Holoenzyme (mouse) TAS Mus musculus 36080 R-MMU-8848658 https://reactome.org/PathwayBrowser/#/R-MMU-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Mus musculus 36080 R-MMU-8850594 https://reactome.org/PathwayBrowser/#/R-MMU-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Mus musculus 36080 R-MMU-8852200 https://reactome.org/PathwayBrowser/#/R-MMU-8852200 Inactivation of LCK by PTPN22 IEA Mus musculus 36080 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus 36080 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus 36080 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 36080 R-MMU-8855381 https://reactome.org/PathwayBrowser/#/R-MMU-8855381 PTPN22 dephosphorylates ZAP70 IEA Mus musculus 36080 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus 36080 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus 36080 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus 36080 R-MMU-9724745 https://reactome.org/PathwayBrowser/#/R-MMU-9724745 PLG(20-810) binds aprotinin IEA Mus musculus 36080 R-MMU-9724753 https://reactome.org/PathwayBrowser/#/R-MMU-9724753 PLG(20-810) binds anti-fibrinolytics IEA Mus musculus 36080 R-MMU-983427 https://reactome.org/PathwayBrowser/#/R-MMU-983427 Expression of peptide bound class I MHC on cell surface IEA Mus musculus 36080 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus 36080 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus 36080 R-MMU-983702 https://reactome.org/PathwayBrowser/#/R-MMU-983702 Phosphorylation of ITAMs of Ig-alpha (Cd79a) and Ig-beta (Cd79b) TAS Mus musculus 36080 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus 36080 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus 36080 R-NUL-212920 https://reactome.org/PathwayBrowser/#/R-NUL-212920 Ubiquitination of PAK-2p34 TAS Oryctolagus cuniculus 36080 R-NUL-2426460 https://reactome.org/PathwayBrowser/#/R-NUL-2426460 Mouse emilin-1 binds human elastin and mouse fibulin-5 TAS Homo sapiens 36080 R-NUL-2731094 https://reactome.org/PathwayBrowser/#/R-NUL-2731094 Syndecan-1 binds collagen types I, III, V TAS Gallus gallus 36080 R-NUL-4084497 https://reactome.org/PathwayBrowser/#/R-NUL-4084497 Collagen VII binds collagen IV TAS Homo sapiens 36080 R-NUL-8867463 https://reactome.org/PathwayBrowser/#/R-NUL-8867463 Ccps deglutamylate tubulin TAS Homo sapiens 36080 R-NUL-8955873 https://reactome.org/PathwayBrowser/#/R-NUL-8955873 Polyglutamylase complex (Ttll1) polyglutamylates alpha subunits of tubulin TAS Homo sapiens 36080 R-NUL-9604617 https://reactome.org/PathwayBrowser/#/R-NUL-9604617 Unknown protein kinase phosphorylates mouse NICD4 TAS Mus musculus 36080 R-NUL-9646387 https://reactome.org/PathwayBrowser/#/R-NUL-9646387 Dynein motors transport misfolded proteins TAS Cercopithecus aethiops 36080 R-PFA-1022127 https://reactome.org/PathwayBrowser/#/R-PFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Plasmodium falciparum 36080 R-PFA-2529015 https://reactome.org/PathwayBrowser/#/R-PFA-2529015 Dephosphorylation of CK2-modified condensin I IEA Plasmodium falciparum 36080 R-PFA-5691512 https://reactome.org/PathwayBrowser/#/R-PFA-5691512 APEH hydrolyses NAc-Ser-protein IEA Plasmodium falciparum 36080 R-PFA-72621 https://reactome.org/PathwayBrowser/#/R-PFA-72621 Ribosomal scanning IEA Plasmodium falciparum 36080 R-PFA-72647 https://reactome.org/PathwayBrowser/#/R-PFA-72647 Cap-bound mRNA is activated by helicases IEA Plasmodium falciparum 36080 R-PFA-72697 https://reactome.org/PathwayBrowser/#/R-PFA-72697 Start codon recognition IEA Plasmodium falciparum 36080 R-RNO-1022127 https://reactome.org/PathwayBrowser/#/R-RNO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Rattus norvegicus 36080 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus 36080 R-RNO-1236964 https://reactome.org/PathwayBrowser/#/R-RNO-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Rattus norvegicus 36080 R-RNO-1236965 https://reactome.org/PathwayBrowser/#/R-RNO-1236965 Export of peptide loaded MHC class I complex to PM IEA Rattus norvegicus 36080 R-RNO-140851 https://reactome.org/PathwayBrowser/#/R-RNO-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Rattus norvegicus 36080 R-RNO-158744 https://reactome.org/PathwayBrowser/#/R-RNO-158744 crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin IEA Rattus norvegicus 36080 R-RNO-158747 https://reactome.org/PathwayBrowser/#/R-RNO-158747 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) IEA Rattus norvegicus 36080 R-RNO-158750 https://reactome.org/PathwayBrowser/#/R-RNO-158750 crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin IEA Rattus norvegicus 36080 R-RNO-158756 https://reactome.org/PathwayBrowser/#/R-RNO-158756 crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen IEA Rattus norvegicus 36080 R-RNO-158766 https://reactome.org/PathwayBrowser/#/R-RNO-158766 fibrin multimer, crosslinked -> fibrin digestion products (plasmin) IEA Rattus norvegicus 36080 R-RNO-158781 https://reactome.org/PathwayBrowser/#/R-RNO-158781 crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) IEA Rattus norvegicus 36080 R-RNO-158784 https://reactome.org/PathwayBrowser/#/R-RNO-158784 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen IEA Rattus norvegicus 36080 R-RNO-158795 https://reactome.org/PathwayBrowser/#/R-RNO-158795 fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 IEA Rattus norvegicus 36080 R-RNO-158800 https://reactome.org/PathwayBrowser/#/R-RNO-158800 fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 IEA Rattus norvegicus 36080 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus 36080 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus 36080 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus 36080 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus 36080 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus 36080 R-RNO-198955 https://reactome.org/PathwayBrowser/#/R-RNO-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Rattus norvegicus 36080 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus 36080 R-RNO-199518 https://reactome.org/PathwayBrowser/#/R-RNO-199518 C3d-complexed antigen binds to complement receptor IEA Rattus norvegicus 36080 R-RNO-202165 https://reactome.org/PathwayBrowser/#/R-RNO-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Rattus norvegicus 36080 R-RNO-202168 https://reactome.org/PathwayBrowser/#/R-RNO-202168 Phosphorylation of ZAP-70 by Lck IEA Rattus norvegicus 36080 R-RNO-202174 https://reactome.org/PathwayBrowser/#/R-RNO-202174 Activation of ZAP-70 IEA Rattus norvegicus 36080 R-RNO-202214 https://reactome.org/PathwayBrowser/#/R-RNO-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Rattus norvegicus 36080 R-RNO-202216 https://reactome.org/PathwayBrowser/#/R-RNO-202216 Phosphorylation of SLP-76 IEA Rattus norvegicus 36080 R-RNO-202233 https://reactome.org/PathwayBrowser/#/R-RNO-202233 Inactivation of Lck by Csk IEA Rattus norvegicus 36080 R-RNO-202245 https://reactome.org/PathwayBrowser/#/R-RNO-202245 Phosphorylation of TBSMs in LAT IEA Rattus norvegicus 36080 R-RNO-202248 https://reactome.org/PathwayBrowser/#/R-RNO-202248 Phosphorylation of PLC-gamma1 IEA Rattus norvegicus 36080 R-RNO-202291 https://reactome.org/PathwayBrowser/#/R-RNO-202291 Activation of Lck IEA Rattus norvegicus 36080 R-RNO-202307 https://reactome.org/PathwayBrowser/#/R-RNO-202307 Change of PKC theta conformation IEA Rattus norvegicus 36080 R-RNO-202344 https://reactome.org/PathwayBrowser/#/R-RNO-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Rattus norvegicus 36080 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus 36080 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus 36080 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 36080 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus 36080 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus 36080 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus 36080 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus 36080 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus 36080 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus 36080 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus 36080 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus 36080 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus 36080 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus 36080 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus 36080 R-RNO-2213240 https://reactome.org/PathwayBrowser/#/R-RNO-2213240 Reduction of disulphide bonds in MHC II antigens IEA Rattus norvegicus 36080 R-RNO-2529015 https://reactome.org/PathwayBrowser/#/R-RNO-2529015 Dephosphorylation of CK2-modified condensin I IEA Rattus norvegicus 36080 R-RNO-389758 https://reactome.org/PathwayBrowser/#/R-RNO-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Rattus norvegicus 36080 R-RNO-5690517 https://reactome.org/PathwayBrowser/#/R-RNO-5690517 PPT1 hydrolyses palmitoylated proteins IEA Rattus norvegicus 36080 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus 36080 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus 36080 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus 36080 R-RNO-5691512 https://reactome.org/PathwayBrowser/#/R-RNO-5691512 APEH hydrolyses NAc-Ser-protein IEA Rattus norvegicus 36080 R-RNO-72621 https://reactome.org/PathwayBrowser/#/R-RNO-72621 Ribosomal scanning IEA Rattus norvegicus 36080 R-RNO-72697 https://reactome.org/PathwayBrowser/#/R-RNO-72697 Start codon recognition IEA Rattus norvegicus 36080 R-RNO-8848658 https://reactome.org/PathwayBrowser/#/R-RNO-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Rattus norvegicus 36080 R-RNO-8850594 https://reactome.org/PathwayBrowser/#/R-RNO-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Rattus norvegicus 36080 R-RNO-8852200 https://reactome.org/PathwayBrowser/#/R-RNO-8852200 Inactivation of LCK by PTPN22 IEA Rattus norvegicus 36080 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus 36080 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus 36080 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 36080 R-RNO-8855381 https://reactome.org/PathwayBrowser/#/R-RNO-8855381 PTPN22 dephosphorylates ZAP70 IEA Rattus norvegicus 36080 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus 36080 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus 36080 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus 36080 R-RNO-9724745 https://reactome.org/PathwayBrowser/#/R-RNO-9724745 PLG(20-810) binds aprotinin IEA Rattus norvegicus 36080 R-RNO-9724753 https://reactome.org/PathwayBrowser/#/R-RNO-9724753 PLG(20-810) binds anti-fibrinolytics IEA Rattus norvegicus 36080 R-RNO-983427 https://reactome.org/PathwayBrowser/#/R-RNO-983427 Expression of peptide bound class I MHC on cell surface IEA Rattus norvegicus 36080 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus 36080 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus 36080 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus 36080 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus 36080 R-SCE-1022127 https://reactome.org/PathwayBrowser/#/R-SCE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Saccharomyces cerevisiae 36080 R-SCE-2529015 https://reactome.org/PathwayBrowser/#/R-SCE-2529015 Dephosphorylation of CK2-modified condensin I IEA Saccharomyces cerevisiae 36080 R-SCE-72621 https://reactome.org/PathwayBrowser/#/R-SCE-72621 Ribosomal scanning IEA Saccharomyces cerevisiae 36080 R-SCE-72647 https://reactome.org/PathwayBrowser/#/R-SCE-72647 Cap-bound mRNA is activated by helicases IEA Saccharomyces cerevisiae 36080 R-SCE-72697 https://reactome.org/PathwayBrowser/#/R-SCE-72697 Start codon recognition IEA Saccharomyces cerevisiae 36080 R-SPO-1022127 https://reactome.org/PathwayBrowser/#/R-SPO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Schizosaccharomyces pombe 36080 R-SPO-2529015 https://reactome.org/PathwayBrowser/#/R-SPO-2529015 Dephosphorylation of CK2-modified condensin I IEA Schizosaccharomyces pombe 36080 R-SPO-72619 https://reactome.org/PathwayBrowser/#/R-SPO-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Schizosaccharomyces pombe 36080 R-SPO-72621 https://reactome.org/PathwayBrowser/#/R-SPO-72621 Ribosomal scanning IEA Schizosaccharomyces pombe 36080 R-SPO-72647 https://reactome.org/PathwayBrowser/#/R-SPO-72647 Cap-bound mRNA is activated by helicases IEA Schizosaccharomyces pombe 36080 R-SPO-72697 https://reactome.org/PathwayBrowser/#/R-SPO-72697 Start codon recognition IEA Schizosaccharomyces pombe 36080 R-SSC-1022127 https://reactome.org/PathwayBrowser/#/R-SSC-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Sus scrofa 36080 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa 36080 R-SSC-1236964 https://reactome.org/PathwayBrowser/#/R-SSC-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Sus scrofa 36080 R-SSC-1236965 https://reactome.org/PathwayBrowser/#/R-SSC-1236965 Export of peptide loaded MHC class I complex to PM IEA Sus scrofa 36080 R-SSC-140851 https://reactome.org/PathwayBrowser/#/R-SSC-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ IEA Sus scrofa 36080 R-SSC-158744 https://reactome.org/PathwayBrowser/#/R-SSC-158744 crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin IEA Sus scrofa 36080 R-SSC-158747 https://reactome.org/PathwayBrowser/#/R-SSC-158747 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) IEA Sus scrofa 36080 R-SSC-158750 https://reactome.org/PathwayBrowser/#/R-SSC-158750 crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin IEA Sus scrofa 36080 R-SSC-158756 https://reactome.org/PathwayBrowser/#/R-SSC-158756 crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen IEA Sus scrofa 36080 R-SSC-158766 https://reactome.org/PathwayBrowser/#/R-SSC-158766 fibrin multimer, crosslinked -> fibrin digestion products (plasmin) IEA Sus scrofa 36080 R-SSC-158781 https://reactome.org/PathwayBrowser/#/R-SSC-158781 crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) IEA Sus scrofa 36080 R-SSC-158784 https://reactome.org/PathwayBrowser/#/R-SSC-158784 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen IEA Sus scrofa 36080 R-SSC-158795 https://reactome.org/PathwayBrowser/#/R-SSC-158795 fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 IEA Sus scrofa 36080 R-SSC-158800 https://reactome.org/PathwayBrowser/#/R-SSC-158800 fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 IEA Sus scrofa 36080 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa 36080 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa 36080 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa 36080 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa 36080 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa 36080 R-SSC-198955 https://reactome.org/PathwayBrowser/#/R-SSC-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Sus scrofa 36080 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa 36080 R-SSC-199518 https://reactome.org/PathwayBrowser/#/R-SSC-199518 C3d-complexed antigen binds to complement receptor IEA Sus scrofa 36080 R-SSC-202165 https://reactome.org/PathwayBrowser/#/R-SSC-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Sus scrofa 36080 R-SSC-202168 https://reactome.org/PathwayBrowser/#/R-SSC-202168 Phosphorylation of ZAP-70 by Lck IEA Sus scrofa 36080 R-SSC-202174 https://reactome.org/PathwayBrowser/#/R-SSC-202174 Activation of ZAP-70 IEA Sus scrofa 36080 R-SSC-202214 https://reactome.org/PathwayBrowser/#/R-SSC-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Sus scrofa 36080 R-SSC-202216 https://reactome.org/PathwayBrowser/#/R-SSC-202216 Phosphorylation of SLP-76 IEA Sus scrofa 36080 R-SSC-202233 https://reactome.org/PathwayBrowser/#/R-SSC-202233 Inactivation of Lck by Csk IEA Sus scrofa 36080 R-SSC-202245 https://reactome.org/PathwayBrowser/#/R-SSC-202245 Phosphorylation of TBSMs in LAT IEA Sus scrofa 36080 R-SSC-202248 https://reactome.org/PathwayBrowser/#/R-SSC-202248 Phosphorylation of PLC-gamma1 IEA Sus scrofa 36080 R-SSC-202291 https://reactome.org/PathwayBrowser/#/R-SSC-202291 Activation of Lck IEA Sus scrofa 36080 R-SSC-202307 https://reactome.org/PathwayBrowser/#/R-SSC-202307 Change of PKC theta conformation IEA Sus scrofa 36080 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa 36080 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa 36080 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 36080 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa 36080 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa 36080 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa 36080 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa 36080 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa 36080 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa 36080 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa 36080 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa 36080 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa 36080 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa 36080 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa 36080 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa 36080 R-SSC-2213240 https://reactome.org/PathwayBrowser/#/R-SSC-2213240 Reduction of disulphide bonds in MHC II antigens IEA Sus scrofa 36080 R-SSC-2529015 https://reactome.org/PathwayBrowser/#/R-SSC-2529015 Dephosphorylation of CK2-modified condensin I IEA Sus scrofa 36080 R-SSC-3132759 https://reactome.org/PathwayBrowser/#/R-SSC-3132759 TCN1 binds RCbl IEA Sus scrofa 36080 R-SSC-389758 https://reactome.org/PathwayBrowser/#/R-SSC-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Sus scrofa 36080 R-SSC-5690517 https://reactome.org/PathwayBrowser/#/R-SSC-5690517 PPT1 hydrolyses palmitoylated proteins IEA Sus scrofa 36080 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa 36080 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa 36080 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa 36080 R-SSC-5691512 https://reactome.org/PathwayBrowser/#/R-SSC-5691512 APEH hydrolyses NAc-Ser-protein IEA Sus scrofa 36080 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa 36080 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa 36080 R-SSC-8848658 https://reactome.org/PathwayBrowser/#/R-SSC-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Sus scrofa 36080 R-SSC-8850594 https://reactome.org/PathwayBrowser/#/R-SSC-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Sus scrofa 36080 R-SSC-8852200 https://reactome.org/PathwayBrowser/#/R-SSC-8852200 Inactivation of LCK by PTPN22 IEA Sus scrofa 36080 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa 36080 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa 36080 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 36080 R-SSC-8855381 https://reactome.org/PathwayBrowser/#/R-SSC-8855381 PTPN22 dephosphorylates ZAP70 IEA Sus scrofa 36080 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa 36080 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa 36080 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa 36080 R-SSC-9724745 https://reactome.org/PathwayBrowser/#/R-SSC-9724745 PLG(20-810) binds aprotinin IEA Sus scrofa 36080 R-SSC-9724753 https://reactome.org/PathwayBrowser/#/R-SSC-9724753 PLG(20-810) binds anti-fibrinolytics IEA Sus scrofa 36080 R-SSC-983427 https://reactome.org/PathwayBrowser/#/R-SSC-983427 Expression of peptide bound class I MHC on cell surface IEA Sus scrofa 36080 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa 36080 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa 36080 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa 36080 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa 36080 R-XTR-1022127 https://reactome.org/PathwayBrowser/#/R-XTR-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Xenopus tropicalis 36080 R-XTR-158766 https://reactome.org/PathwayBrowser/#/R-XTR-158766 fibrin multimer, crosslinked -> fibrin digestion products (plasmin) IEA Xenopus tropicalis 36080 R-XTR-2213240 https://reactome.org/PathwayBrowser/#/R-XTR-2213240 Reduction of disulphide bonds in MHC II antigens IEA Xenopus tropicalis 36080 R-XTR-3132759 https://reactome.org/PathwayBrowser/#/R-XTR-3132759 TCN1 binds RCbl IEA Xenopus tropicalis 36080 R-XTR-5690517 https://reactome.org/PathwayBrowser/#/R-XTR-5690517 PPT1 hydrolyses palmitoylated proteins IEA Xenopus tropicalis 36080 R-XTR-5691512 https://reactome.org/PathwayBrowser/#/R-XTR-5691512 APEH hydrolyses NAc-Ser-protein IEA Xenopus tropicalis 36080 R-XTR-72621 https://reactome.org/PathwayBrowser/#/R-XTR-72621 Ribosomal scanning IEA Xenopus tropicalis 36080 R-XTR-72697 https://reactome.org/PathwayBrowser/#/R-XTR-72697 Start codon recognition IEA Xenopus tropicalis 36080 R-XTR-8848658 https://reactome.org/PathwayBrowser/#/R-XTR-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Xenopus tropicalis 36080 R-XTR-8850594 https://reactome.org/PathwayBrowser/#/R-XTR-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Xenopus tropicalis 36080 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 3614 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 3614 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 3614 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 3614 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 3614 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 3614 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 3614 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 3614 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 3614 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 3614 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 36141 R-BTA-8936519 https://reactome.org/PathwayBrowser/#/R-BTA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Bos taurus 36141 R-CFA-8936519 https://reactome.org/PathwayBrowser/#/R-CFA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Canis familiaris 36141 R-GGA-8936519 https://reactome.org/PathwayBrowser/#/R-GGA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Gallus gallus 36141 R-HSA-8936519 https://reactome.org/PathwayBrowser/#/R-HSA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones TAS Homo sapiens 36141 R-MMU-8936519 https://reactome.org/PathwayBrowser/#/R-MMU-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Mus musculus 36141 R-RNO-8936519 https://reactome.org/PathwayBrowser/#/R-RNO-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Rattus norvegicus 36141 R-SSC-8936519 https://reactome.org/PathwayBrowser/#/R-SSC-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Sus scrofa 36141 R-XTR-8936519 https://reactome.org/PathwayBrowser/#/R-XTR-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Xenopus tropicalis 36144 R-BTA-198824 https://reactome.org/PathwayBrowser/#/R-BTA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Bos taurus 36144 R-BTA-198845 https://reactome.org/PathwayBrowser/#/R-BTA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Bos taurus 36144 R-BTA-2168884 https://reactome.org/PathwayBrowser/#/R-BTA-2168884 Ferriheme is transferred from Methemoglobin to Hemopexin IEA Bos taurus 36144 R-BTA-2168886 https://reactome.org/PathwayBrowser/#/R-BTA-2168886 Hemopexin binds Hemes IEA Bos taurus 36144 R-BTA-2168887 https://reactome.org/PathwayBrowser/#/R-BTA-2168887 Ferriheme is transferred from Albumin to Hemopexin IEA Bos taurus 36144 R-BTA-2168897 https://reactome.org/PathwayBrowser/#/R-BTA-2168897 LRP1 (CD91) binds Hemopexin:heme IEA Bos taurus 36144 R-BTA-2230983 https://reactome.org/PathwayBrowser/#/R-BTA-2230983 LRP1:Hemopexin:heme is endocytosed IEA Bos taurus 36144 R-BTA-6806831 https://reactome.org/PathwayBrowser/#/R-BTA-6806831 CYB5Rs reduce MetHb to HbA IEA Bos taurus 36144 R-BTA-917870 https://reactome.org/PathwayBrowser/#/R-BTA-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Bos taurus 36144 R-BTA-9707504 https://reactome.org/PathwayBrowser/#/R-BTA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Bos taurus 36144 R-BTA-9707505 https://reactome.org/PathwayBrowser/#/R-BTA-9707505 Hemes bind to CLEC1B dimer IEA Bos taurus 36144 R-BTA-9707516 https://reactome.org/PathwayBrowser/#/R-BTA-9707516 FeHM dissociates from MetHb IEA Bos taurus 36144 R-BTA-9707523 https://reactome.org/PathwayBrowser/#/R-BTA-9707523 Hemes bind to BACH1:MAFK IEA Bos taurus 36144 R-BTA-9707586 https://reactome.org/PathwayBrowser/#/R-BTA-9707586 FeHM oxidises LDL,HDL IEA Bos taurus 36144 R-BTA-9707594 https://reactome.org/PathwayBrowser/#/R-BTA-9707594 Hemes bind LY96 IEA Bos taurus 36144 R-BTA-9707606 https://reactome.org/PathwayBrowser/#/R-BTA-9707606 PGRMC2:Hemes translocate to the nucleus IEA Bos taurus 36144 R-BTA-9707659 https://reactome.org/PathwayBrowser/#/R-BTA-9707659 Hemes:LY96 activates TLR4 IEA Bos taurus 36144 R-BTA-9707683 https://reactome.org/PathwayBrowser/#/R-BTA-9707683 PGRMC2 binds Hemes IEA Bos taurus 36144 R-BTA-9707856 https://reactome.org/PathwayBrowser/#/R-BTA-9707856 PGRMC2:Hemes dissociates IEA Bos taurus 36144 R-BTA-9708423 https://reactome.org/PathwayBrowser/#/R-BTA-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Bos taurus 36144 R-BTA-9708430 https://reactome.org/PathwayBrowser/#/R-BTA-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Bos taurus 36144 R-BTA-9709360 https://reactome.org/PathwayBrowser/#/R-BTA-9709360 H2O2 reduces MetHb IEA Bos taurus 36144 R-CEL-198845 https://reactome.org/PathwayBrowser/#/R-CEL-198845 CYB5A:heme reduces Asc.- to AscH- IEA Caenorhabditis elegans 36144 R-CEL-2168886 https://reactome.org/PathwayBrowser/#/R-CEL-2168886 Hemopexin binds Hemes IEA Caenorhabditis elegans 36144 R-CEL-917870 https://reactome.org/PathwayBrowser/#/R-CEL-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Caenorhabditis elegans 36144 R-CEL-9707505 https://reactome.org/PathwayBrowser/#/R-CEL-9707505 Hemes bind to CLEC1B dimer IEA Caenorhabditis elegans 36144 R-CEL-9707606 https://reactome.org/PathwayBrowser/#/R-CEL-9707606 PGRMC2:Hemes translocate to the nucleus IEA Caenorhabditis elegans 36144 R-CEL-9707683 https://reactome.org/PathwayBrowser/#/R-CEL-9707683 PGRMC2 binds Hemes IEA Caenorhabditis elegans 36144 R-CEL-9707856 https://reactome.org/PathwayBrowser/#/R-CEL-9707856 PGRMC2:Hemes dissociates IEA Caenorhabditis elegans 36144 R-CFA-198824 https://reactome.org/PathwayBrowser/#/R-CFA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Canis familiaris 36144 R-CFA-198845 https://reactome.org/PathwayBrowser/#/R-CFA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Canis familiaris 36144 R-CFA-6806831 https://reactome.org/PathwayBrowser/#/R-CFA-6806831 CYB5Rs reduce MetHb to HbA IEA Canis familiaris 36144 R-CFA-917870 https://reactome.org/PathwayBrowser/#/R-CFA-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Canis familiaris 36144 R-CFA-9707504 https://reactome.org/PathwayBrowser/#/R-CFA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Canis familiaris 36144 R-CFA-9707505 https://reactome.org/PathwayBrowser/#/R-CFA-9707505 Hemes bind to CLEC1B dimer IEA Canis familiaris 36144 R-CFA-9707516 https://reactome.org/PathwayBrowser/#/R-CFA-9707516 FeHM dissociates from MetHb IEA Canis familiaris 36144 R-CFA-9707523 https://reactome.org/PathwayBrowser/#/R-CFA-9707523 Hemes bind to BACH1:MAFK IEA Canis familiaris 36144 R-CFA-9707586 https://reactome.org/PathwayBrowser/#/R-CFA-9707586 FeHM oxidises LDL,HDL IEA Canis familiaris 36144 R-CFA-9707594 https://reactome.org/PathwayBrowser/#/R-CFA-9707594 Hemes bind LY96 IEA Canis familiaris 36144 R-CFA-9707606 https://reactome.org/PathwayBrowser/#/R-CFA-9707606 PGRMC2:Hemes translocate to the nucleus IEA Canis familiaris 36144 R-CFA-9707659 https://reactome.org/PathwayBrowser/#/R-CFA-9707659 Hemes:LY96 activates TLR4 IEA Canis familiaris 36144 R-CFA-9707683 https://reactome.org/PathwayBrowser/#/R-CFA-9707683 PGRMC2 binds Hemes IEA Canis familiaris 36144 R-CFA-9707856 https://reactome.org/PathwayBrowser/#/R-CFA-9707856 PGRMC2:Hemes dissociates IEA Canis familiaris 36144 R-CFA-9708423 https://reactome.org/PathwayBrowser/#/R-CFA-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Canis familiaris 36144 R-CFA-9708430 https://reactome.org/PathwayBrowser/#/R-CFA-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Canis familiaris 36144 R-CFA-9709360 https://reactome.org/PathwayBrowser/#/R-CFA-9709360 H2O2 reduces MetHb IEA Canis familiaris 36144 R-DDI-198824 https://reactome.org/PathwayBrowser/#/R-DDI-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Dictyostelium discoideum 36144 R-DDI-198845 https://reactome.org/PathwayBrowser/#/R-DDI-198845 CYB5A:heme reduces Asc.- to AscH- IEA Dictyostelium discoideum 36144 R-DDI-9707606 https://reactome.org/PathwayBrowser/#/R-DDI-9707606 PGRMC2:Hemes translocate to the nucleus IEA Dictyostelium discoideum 36144 R-DDI-9707683 https://reactome.org/PathwayBrowser/#/R-DDI-9707683 PGRMC2 binds Hemes IEA Dictyostelium discoideum 36144 R-DDI-9707856 https://reactome.org/PathwayBrowser/#/R-DDI-9707856 PGRMC2:Hemes dissociates IEA Dictyostelium discoideum 36144 R-DME-198824 https://reactome.org/PathwayBrowser/#/R-DME-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Drosophila melanogaster 36144 R-DME-198845 https://reactome.org/PathwayBrowser/#/R-DME-198845 CYB5A:heme reduces Asc.- to AscH- IEA Drosophila melanogaster 36144 R-DME-2168886 https://reactome.org/PathwayBrowser/#/R-DME-2168886 Hemopexin binds Hemes IEA Drosophila melanogaster 36144 R-DME-917870 https://reactome.org/PathwayBrowser/#/R-DME-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Drosophila melanogaster 36144 R-DME-9707523 https://reactome.org/PathwayBrowser/#/R-DME-9707523 Hemes bind to BACH1:MAFK IEA Drosophila melanogaster 36144 R-DME-9707606 https://reactome.org/PathwayBrowser/#/R-DME-9707606 PGRMC2:Hemes translocate to the nucleus IEA Drosophila melanogaster 36144 R-DME-9707683 https://reactome.org/PathwayBrowser/#/R-DME-9707683 PGRMC2 binds Hemes IEA Drosophila melanogaster 36144 R-DME-9707856 https://reactome.org/PathwayBrowser/#/R-DME-9707856 PGRMC2:Hemes dissociates IEA Drosophila melanogaster 36144 R-DME-9708423 https://reactome.org/PathwayBrowser/#/R-DME-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Drosophila melanogaster 36144 R-DME-9708430 https://reactome.org/PathwayBrowser/#/R-DME-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Drosophila melanogaster 36144 R-DRE-198824 https://reactome.org/PathwayBrowser/#/R-DRE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Danio rerio 36144 R-DRE-198845 https://reactome.org/PathwayBrowser/#/R-DRE-198845 CYB5A:heme reduces Asc.- to AscH- IEA Danio rerio 36144 R-DRE-6806831 https://reactome.org/PathwayBrowser/#/R-DRE-6806831 CYB5Rs reduce MetHb to HbA IEA Danio rerio 36144 R-DRE-917870 https://reactome.org/PathwayBrowser/#/R-DRE-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Danio rerio 36144 R-DRE-9707504 https://reactome.org/PathwayBrowser/#/R-DRE-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Danio rerio 36144 R-DRE-9707516 https://reactome.org/PathwayBrowser/#/R-DRE-9707516 FeHM dissociates from MetHb IEA Danio rerio 36144 R-DRE-9707606 https://reactome.org/PathwayBrowser/#/R-DRE-9707606 PGRMC2:Hemes translocate to the nucleus IEA Danio rerio 36144 R-DRE-9707683 https://reactome.org/PathwayBrowser/#/R-DRE-9707683 PGRMC2 binds Hemes IEA Danio rerio 36144 R-DRE-9707856 https://reactome.org/PathwayBrowser/#/R-DRE-9707856 PGRMC2:Hemes dissociates IEA Danio rerio 36144 R-DRE-9709360 https://reactome.org/PathwayBrowser/#/R-DRE-9709360 H2O2 reduces MetHb IEA Danio rerio 36144 R-GGA-198824 https://reactome.org/PathwayBrowser/#/R-GGA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Gallus gallus 36144 R-GGA-198845 https://reactome.org/PathwayBrowser/#/R-GGA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Gallus gallus 36144 R-GGA-6806831 https://reactome.org/PathwayBrowser/#/R-GGA-6806831 CYB5Rs reduce MetHb to HbA IEA Gallus gallus 36144 R-GGA-917870 https://reactome.org/PathwayBrowser/#/R-GGA-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Gallus gallus 36144 R-GGA-9707504 https://reactome.org/PathwayBrowser/#/R-GGA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Gallus gallus 36144 R-GGA-9707516 https://reactome.org/PathwayBrowser/#/R-GGA-9707516 FeHM dissociates from MetHb IEA Gallus gallus 36144 R-GGA-9707523 https://reactome.org/PathwayBrowser/#/R-GGA-9707523 Hemes bind to BACH1:MAFK IEA Gallus gallus 36144 R-GGA-9707586 https://reactome.org/PathwayBrowser/#/R-GGA-9707586 FeHM oxidises LDL,HDL IEA Gallus gallus 36144 R-GGA-9707594 https://reactome.org/PathwayBrowser/#/R-GGA-9707594 Hemes bind LY96 IEA Gallus gallus 36144 R-GGA-9707606 https://reactome.org/PathwayBrowser/#/R-GGA-9707606 PGRMC2:Hemes translocate to the nucleus IEA Gallus gallus 36144 R-GGA-9707659 https://reactome.org/PathwayBrowser/#/R-GGA-9707659 Hemes:LY96 activates TLR4 IEA Gallus gallus 36144 R-GGA-9707683 https://reactome.org/PathwayBrowser/#/R-GGA-9707683 PGRMC2 binds Hemes IEA Gallus gallus 36144 R-GGA-9707856 https://reactome.org/PathwayBrowser/#/R-GGA-9707856 PGRMC2:Hemes dissociates IEA Gallus gallus 36144 R-GGA-9708423 https://reactome.org/PathwayBrowser/#/R-GGA-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Gallus gallus 36144 R-GGA-9708430 https://reactome.org/PathwayBrowser/#/R-GGA-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Gallus gallus 36144 R-GGA-9709360 https://reactome.org/PathwayBrowser/#/R-GGA-9709360 H2O2 reduces MetHb IEA Gallus gallus 36144 R-HSA-1222512 https://reactome.org/PathwayBrowser/#/R-HSA-1222512 Nitric oxide oxidizes to nitrosyl ion TAS Homo sapiens 36144 R-HSA-1222723 https://reactome.org/PathwayBrowser/#/R-HSA-1222723 Nitric oxide is oxidized to nitrate TAS Homo sapiens 36144 R-HSA-1368065 https://reactome.org/PathwayBrowser/#/R-HSA-1368065 Expression of NPAS2 IEA Homo sapiens 36144 R-HSA-1368069 https://reactome.org/PathwayBrowser/#/R-HSA-1368069 NR1D1 (REV-ERBA) binds heme, the ARNTL gene, and recruits corepressors. TAS Homo sapiens 36144 R-HSA-1368119 https://reactome.org/PathwayBrowser/#/R-HSA-1368119 Expression of CLOCK IEA Homo sapiens 36144 R-HSA-1368140 https://reactome.org/PathwayBrowser/#/R-HSA-1368140 Expression of PPARGC1A (PGC-1alpha) IEA Homo sapiens 36144 R-HSA-198824 https://reactome.org/PathwayBrowser/#/R-HSA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme TAS Homo sapiens 36144 R-HSA-198845 https://reactome.org/PathwayBrowser/#/R-HSA-198845 CYB5A:heme reduces Asc.- to AscH- TAS Homo sapiens 36144 R-HSA-2168884 https://reactome.org/PathwayBrowser/#/R-HSA-2168884 Ferriheme is transferred from Methemoglobin to Hemopexin TAS Homo sapiens 36144 R-HSA-2168886 https://reactome.org/PathwayBrowser/#/R-HSA-2168886 Hemopexin binds Hemes TAS Homo sapiens 36144 R-HSA-2168887 https://reactome.org/PathwayBrowser/#/R-HSA-2168887 Ferriheme is transferred from Albumin to Hemopexin TAS Homo sapiens 36144 R-HSA-2168897 https://reactome.org/PathwayBrowser/#/R-HSA-2168897 LRP1 (CD91) binds Hemopexin:heme TAS Homo sapiens 36144 R-HSA-2230983 https://reactome.org/PathwayBrowser/#/R-HSA-2230983 LRP1:Hemopexin:heme is endocytosed TAS Homo sapiens 36144 R-HSA-400342 https://reactome.org/PathwayBrowser/#/R-HSA-400342 Expression of ARNTL (BMAL1) IEA Homo sapiens 36144 R-HSA-549475 https://reactome.org/PathwayBrowser/#/R-HSA-549475 Expression of NR1D1 (REV-ERBA) IEA Homo sapiens 36144 R-HSA-5663245 https://reactome.org/PathwayBrowser/#/R-HSA-5663245 NR1D1 (REV-ERBA) binds heme, the NPAS2 gene, and recruits corepressors TAS Homo sapiens 36144 R-HSA-5663252 https://reactome.org/PathwayBrowser/#/R-HSA-5663252 NR1D1 (REV-ERBA) binds heme, the ELOVL3 gene, and recruits corepressors IEA Homo sapiens 36144 R-HSA-5663258 https://reactome.org/PathwayBrowser/#/R-HSA-5663258 NR1D1 (REV-ERBA) binds heme, the PPARGC1A gene, and recruits corepressors TAS Homo sapiens 36144 R-HSA-5663265 https://reactome.org/PathwayBrowser/#/R-HSA-5663265 NR1D1 (REV-ERBA) binds heme, the NR1D1 gene, and recruits corepressors TAS Homo sapiens 36144 R-HSA-5663271 https://reactome.org/PathwayBrowser/#/R-HSA-5663271 NR1D1 (REV-ERBA) binds heme, the CLOCK gene, and recruits corepressors TAS Homo sapiens 36144 R-HSA-6806831 https://reactome.org/PathwayBrowser/#/R-HSA-6806831 CYB5Rs reduce MetHb to HbA TAS Homo sapiens 36144 R-HSA-917870 https://reactome.org/PathwayBrowser/#/R-HSA-917870 SLC46A1 transports hemes from extracellular region to cytosol TAS Homo sapiens 36144 R-HSA-9648880 https://reactome.org/PathwayBrowser/#/R-HSA-9648880 Ferriheme dissociates from p-T-EIF2AK1:2xferriheme dimer IEA Homo sapiens 36144 R-HSA-9648883 https://reactome.org/PathwayBrowser/#/R-HSA-9648883 p-T-EIF2AK1:ferriheme dimer autophosphorylates IEA Homo sapiens 36144 R-HSA-9648888 https://reactome.org/PathwayBrowser/#/R-HSA-9648888 p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) IEA Homo sapiens 36144 R-HSA-9707504 https://reactome.org/PathwayBrowser/#/R-HSA-9707504 H2O2 oxidises ferrohemoglobin to MetHb TAS Homo sapiens 36144 R-HSA-9707505 https://reactome.org/PathwayBrowser/#/R-HSA-9707505 Hemes bind to CLEC1B dimer TAS Homo sapiens 36144 R-HSA-9707516 https://reactome.org/PathwayBrowser/#/R-HSA-9707516 FeHM dissociates from MetHb TAS Homo sapiens 36144 R-HSA-9707523 https://reactome.org/PathwayBrowser/#/R-HSA-9707523 Hemes bind to BACH1:MAFK TAS Homo sapiens 36144 R-HSA-9707586 https://reactome.org/PathwayBrowser/#/R-HSA-9707586 FeHM oxidises LDL,HDL TAS Homo sapiens 36144 R-HSA-9707594 https://reactome.org/PathwayBrowser/#/R-HSA-9707594 Hemes bind LY96 TAS Homo sapiens 36144 R-HSA-9707606 https://reactome.org/PathwayBrowser/#/R-HSA-9707606 PGRMC2:Hemes translocate to the nucleus TAS Homo sapiens 36144 R-HSA-9707659 https://reactome.org/PathwayBrowser/#/R-HSA-9707659 Hemes:LY96 activates TLR4 TAS Homo sapiens 36144 R-HSA-9707683 https://reactome.org/PathwayBrowser/#/R-HSA-9707683 PGRMC2 binds Hemes TAS Homo sapiens 36144 R-HSA-9707856 https://reactome.org/PathwayBrowser/#/R-HSA-9707856 PGRMC2:Hemes dissociates TAS Homo sapiens 36144 R-HSA-9708423 https://reactome.org/PathwayBrowser/#/R-HSA-9708423 XPO1:BACH1:Hemes are transported out of the nucleus TAS Homo sapiens 36144 R-HSA-9708430 https://reactome.org/PathwayBrowser/#/R-HSA-9708430 XPO1 (CRM1) binds to BACH1:Hemes TAS Homo sapiens 36144 R-HSA-9709360 https://reactome.org/PathwayBrowser/#/R-HSA-9709360 H2O2 reduces MetHb TAS Homo sapiens 36144 R-MMU-198824 https://reactome.org/PathwayBrowser/#/R-MMU-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Mus musculus 36144 R-MMU-198845 https://reactome.org/PathwayBrowser/#/R-MMU-198845 CYB5A:heme reduces Asc.- to AscH- IEA Mus musculus 36144 R-MMU-2168884 https://reactome.org/PathwayBrowser/#/R-MMU-2168884 Ferriheme is transferred from Methemoglobin to Hemopexin IEA Mus musculus 36144 R-MMU-2168886 https://reactome.org/PathwayBrowser/#/R-MMU-2168886 Hemopexin binds Hemes IEA Mus musculus 36144 R-MMU-2168887 https://reactome.org/PathwayBrowser/#/R-MMU-2168887 Ferriheme is transferred from Albumin to Hemopexin IEA Mus musculus 36144 R-MMU-2168897 https://reactome.org/PathwayBrowser/#/R-MMU-2168897 LRP1 (CD91) binds Hemopexin:heme IEA Mus musculus 36144 R-MMU-2230983 https://reactome.org/PathwayBrowser/#/R-MMU-2230983 LRP1:Hemopexin:heme is endocytosed IEA Mus musculus 36144 R-MMU-508681 https://reactome.org/PathwayBrowser/#/R-MMU-508681 Expression of Bmal1 (Arntl) TAS Mus musculus 36144 R-MMU-549505 https://reactome.org/PathwayBrowser/#/R-MMU-549505 Expression of Nr1d1 (Rev-erba) TAS Mus musculus 36144 R-MMU-5663263 https://reactome.org/PathwayBrowser/#/R-MMU-5663263 Expression of Npas2 TAS Mus musculus 36144 R-MMU-5667072 https://reactome.org/PathwayBrowser/#/R-MMU-5667072 Expression of Clock TAS Mus musculus 36144 R-MMU-5667077 https://reactome.org/PathwayBrowser/#/R-MMU-5667077 Nr1d1 (Rev-erba) binds heme, the Elovl3 gene, and recruits corepressors TAS Mus musculus 36144 R-MMU-6806831 https://reactome.org/PathwayBrowser/#/R-MMU-6806831 CYB5Rs reduce MetHb to HbA IEA Mus musculus 36144 R-MMU-917870 https://reactome.org/PathwayBrowser/#/R-MMU-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Mus musculus 36144 R-MMU-9655549 https://reactome.org/PathwayBrowser/#/R-MMU-9655549 p-T-Eif2ak1:ferriheme dimer autophosphorylates TAS Mus musculus 36144 R-MMU-9655598 https://reactome.org/PathwayBrowser/#/R-MMU-9655598 Ferriheme dissociates from p-T-Eif2ak1:2xferriheme dimer TAS Mus musculus 36144 R-MMU-9707504 https://reactome.org/PathwayBrowser/#/R-MMU-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Mus musculus 36144 R-MMU-9707505 https://reactome.org/PathwayBrowser/#/R-MMU-9707505 Hemes bind to CLEC1B dimer IEA Mus musculus 36144 R-MMU-9707516 https://reactome.org/PathwayBrowser/#/R-MMU-9707516 FeHM dissociates from MetHb IEA Mus musculus 36144 R-MMU-9707523 https://reactome.org/PathwayBrowser/#/R-MMU-9707523 Hemes bind to BACH1:MAFK IEA Mus musculus 36144 R-MMU-9707586 https://reactome.org/PathwayBrowser/#/R-MMU-9707586 FeHM oxidises LDL,HDL IEA Mus musculus 36144 R-MMU-9707594 https://reactome.org/PathwayBrowser/#/R-MMU-9707594 Hemes bind LY96 IEA Mus musculus 36144 R-MMU-9707606 https://reactome.org/PathwayBrowser/#/R-MMU-9707606 PGRMC2:Hemes translocate to the nucleus IEA Mus musculus 36144 R-MMU-9707659 https://reactome.org/PathwayBrowser/#/R-MMU-9707659 Hemes:LY96 activates TLR4 IEA Mus musculus 36144 R-MMU-9707683 https://reactome.org/PathwayBrowser/#/R-MMU-9707683 PGRMC2 binds Hemes IEA Mus musculus 36144 R-MMU-9707856 https://reactome.org/PathwayBrowser/#/R-MMU-9707856 PGRMC2:Hemes dissociates IEA Mus musculus 36144 R-MMU-9708423 https://reactome.org/PathwayBrowser/#/R-MMU-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Mus musculus 36144 R-MMU-9708430 https://reactome.org/PathwayBrowser/#/R-MMU-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Mus musculus 36144 R-MMU-9709360 https://reactome.org/PathwayBrowser/#/R-MMU-9709360 H2O2 reduces MetHb IEA Mus musculus 36144 R-OCU-9655573 https://reactome.org/PathwayBrowser/#/R-OCU-9655573 Ferriheme dissociates from p-T-EIF2AK1:2xferriheme dimer TAS Oryctolagus cuniculus 36144 R-RNO-198824 https://reactome.org/PathwayBrowser/#/R-RNO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Rattus norvegicus 36144 R-RNO-198845 https://reactome.org/PathwayBrowser/#/R-RNO-198845 CYB5A:heme reduces Asc.- to AscH- IEA Rattus norvegicus 36144 R-RNO-2168884 https://reactome.org/PathwayBrowser/#/R-RNO-2168884 Ferriheme is transferred from Methemoglobin to Hemopexin IEA Rattus norvegicus 36144 R-RNO-2168886 https://reactome.org/PathwayBrowser/#/R-RNO-2168886 Hemopexin binds Hemes IEA Rattus norvegicus 36144 R-RNO-2168887 https://reactome.org/PathwayBrowser/#/R-RNO-2168887 Ferriheme is transferred from Albumin to Hemopexin IEA Rattus norvegicus 36144 R-RNO-2168897 https://reactome.org/PathwayBrowser/#/R-RNO-2168897 LRP1 (CD91) binds Hemopexin:heme IEA Rattus norvegicus 36144 R-RNO-2230983 https://reactome.org/PathwayBrowser/#/R-RNO-2230983 LRP1:Hemopexin:heme is endocytosed IEA Rattus norvegicus 36144 R-RNO-6806831 https://reactome.org/PathwayBrowser/#/R-RNO-6806831 CYB5Rs reduce MetHb to HbA IEA Rattus norvegicus 36144 R-RNO-917870 https://reactome.org/PathwayBrowser/#/R-RNO-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Rattus norvegicus 36144 R-RNO-9707504 https://reactome.org/PathwayBrowser/#/R-RNO-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Rattus norvegicus 36144 R-RNO-9707505 https://reactome.org/PathwayBrowser/#/R-RNO-9707505 Hemes bind to CLEC1B dimer IEA Rattus norvegicus 36144 R-RNO-9707516 https://reactome.org/PathwayBrowser/#/R-RNO-9707516 FeHM dissociates from MetHb IEA Rattus norvegicus 36144 R-RNO-9707586 https://reactome.org/PathwayBrowser/#/R-RNO-9707586 FeHM oxidises LDL,HDL IEA Rattus norvegicus 36144 R-RNO-9707594 https://reactome.org/PathwayBrowser/#/R-RNO-9707594 Hemes bind LY96 IEA Rattus norvegicus 36144 R-RNO-9707606 https://reactome.org/PathwayBrowser/#/R-RNO-9707606 PGRMC2:Hemes translocate to the nucleus IEA Rattus norvegicus 36144 R-RNO-9707659 https://reactome.org/PathwayBrowser/#/R-RNO-9707659 Hemes:LY96 activates TLR4 IEA Rattus norvegicus 36144 R-RNO-9707683 https://reactome.org/PathwayBrowser/#/R-RNO-9707683 PGRMC2 binds Hemes IEA Rattus norvegicus 36144 R-RNO-9707856 https://reactome.org/PathwayBrowser/#/R-RNO-9707856 PGRMC2:Hemes dissociates IEA Rattus norvegicus 36144 R-RNO-9708423 https://reactome.org/PathwayBrowser/#/R-RNO-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Rattus norvegicus 36144 R-RNO-9708430 https://reactome.org/PathwayBrowser/#/R-RNO-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Rattus norvegicus 36144 R-RNO-9709360 https://reactome.org/PathwayBrowser/#/R-RNO-9709360 H2O2 reduces MetHb IEA Rattus norvegicus 36144 R-SCE-198824 https://reactome.org/PathwayBrowser/#/R-SCE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Saccharomyces cerevisiae 36144 R-SCE-198845 https://reactome.org/PathwayBrowser/#/R-SCE-198845 CYB5A:heme reduces Asc.- to AscH- IEA Saccharomyces cerevisiae 36144 R-SCE-917870 https://reactome.org/PathwayBrowser/#/R-SCE-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Saccharomyces cerevisiae 36144 R-SCE-9707606 https://reactome.org/PathwayBrowser/#/R-SCE-9707606 PGRMC2:Hemes translocate to the nucleus IEA Saccharomyces cerevisiae 36144 R-SCE-9707683 https://reactome.org/PathwayBrowser/#/R-SCE-9707683 PGRMC2 binds Hemes IEA Saccharomyces cerevisiae 36144 R-SCE-9707856 https://reactome.org/PathwayBrowser/#/R-SCE-9707856 PGRMC2:Hemes dissociates IEA Saccharomyces cerevisiae 36144 R-SPO-198824 https://reactome.org/PathwayBrowser/#/R-SPO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Schizosaccharomyces pombe 36144 R-SPO-198845 https://reactome.org/PathwayBrowser/#/R-SPO-198845 CYB5A:heme reduces Asc.- to AscH- IEA Schizosaccharomyces pombe 36144 R-SPO-917870 https://reactome.org/PathwayBrowser/#/R-SPO-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Schizosaccharomyces pombe 36144 R-SPO-9707606 https://reactome.org/PathwayBrowser/#/R-SPO-9707606 PGRMC2:Hemes translocate to the nucleus IEA Schizosaccharomyces pombe 36144 R-SPO-9707683 https://reactome.org/PathwayBrowser/#/R-SPO-9707683 PGRMC2 binds Hemes IEA Schizosaccharomyces pombe 36144 R-SPO-9707856 https://reactome.org/PathwayBrowser/#/R-SPO-9707856 PGRMC2:Hemes dissociates IEA Schizosaccharomyces pombe 36144 R-SSC-198824 https://reactome.org/PathwayBrowser/#/R-SSC-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Sus scrofa 36144 R-SSC-198845 https://reactome.org/PathwayBrowser/#/R-SSC-198845 CYB5A:heme reduces Asc.- to AscH- IEA Sus scrofa 36144 R-SSC-2168884 https://reactome.org/PathwayBrowser/#/R-SSC-2168884 Ferriheme is transferred from Methemoglobin to Hemopexin IEA Sus scrofa 36144 R-SSC-2168886 https://reactome.org/PathwayBrowser/#/R-SSC-2168886 Hemopexin binds Hemes IEA Sus scrofa 36144 R-SSC-2168887 https://reactome.org/PathwayBrowser/#/R-SSC-2168887 Ferriheme is transferred from Albumin to Hemopexin IEA Sus scrofa 36144 R-SSC-6806831 https://reactome.org/PathwayBrowser/#/R-SSC-6806831 CYB5Rs reduce MetHb to HbA IEA Sus scrofa 36144 R-SSC-917870 https://reactome.org/PathwayBrowser/#/R-SSC-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Sus scrofa 36144 R-SSC-9707504 https://reactome.org/PathwayBrowser/#/R-SSC-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Sus scrofa 36144 R-SSC-9707505 https://reactome.org/PathwayBrowser/#/R-SSC-9707505 Hemes bind to CLEC1B dimer IEA Sus scrofa 36144 R-SSC-9707516 https://reactome.org/PathwayBrowser/#/R-SSC-9707516 FeHM dissociates from MetHb IEA Sus scrofa 36144 R-SSC-9707523 https://reactome.org/PathwayBrowser/#/R-SSC-9707523 Hemes bind to BACH1:MAFK IEA Sus scrofa 36144 R-SSC-9707586 https://reactome.org/PathwayBrowser/#/R-SSC-9707586 FeHM oxidises LDL,HDL IEA Sus scrofa 36144 R-SSC-9707594 https://reactome.org/PathwayBrowser/#/R-SSC-9707594 Hemes bind LY96 IEA Sus scrofa 36144 R-SSC-9707606 https://reactome.org/PathwayBrowser/#/R-SSC-9707606 PGRMC2:Hemes translocate to the nucleus IEA Sus scrofa 36144 R-SSC-9707659 https://reactome.org/PathwayBrowser/#/R-SSC-9707659 Hemes:LY96 activates TLR4 IEA Sus scrofa 36144 R-SSC-9707683 https://reactome.org/PathwayBrowser/#/R-SSC-9707683 PGRMC2 binds Hemes IEA Sus scrofa 36144 R-SSC-9707856 https://reactome.org/PathwayBrowser/#/R-SSC-9707856 PGRMC2:Hemes dissociates IEA Sus scrofa 36144 R-SSC-9708423 https://reactome.org/PathwayBrowser/#/R-SSC-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Sus scrofa 36144 R-SSC-9708430 https://reactome.org/PathwayBrowser/#/R-SSC-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Sus scrofa 36144 R-SSC-9709360 https://reactome.org/PathwayBrowser/#/R-SSC-9709360 H2O2 reduces MetHb IEA Sus scrofa 36144 R-XTR-198824 https://reactome.org/PathwayBrowser/#/R-XTR-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Xenopus tropicalis 36144 R-XTR-198845 https://reactome.org/PathwayBrowser/#/R-XTR-198845 CYB5A:heme reduces Asc.- to AscH- IEA Xenopus tropicalis 36144 R-XTR-2168884 https://reactome.org/PathwayBrowser/#/R-XTR-2168884 Ferriheme is transferred from Methemoglobin to Hemopexin IEA Xenopus tropicalis 36144 R-XTR-2168886 https://reactome.org/PathwayBrowser/#/R-XTR-2168886 Hemopexin binds Hemes IEA Xenopus tropicalis 36144 R-XTR-2168887 https://reactome.org/PathwayBrowser/#/R-XTR-2168887 Ferriheme is transferred from Albumin to Hemopexin IEA Xenopus tropicalis 36144 R-XTR-6806831 https://reactome.org/PathwayBrowser/#/R-XTR-6806831 CYB5Rs reduce MetHb to HbA IEA Xenopus tropicalis 36144 R-XTR-917870 https://reactome.org/PathwayBrowser/#/R-XTR-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Xenopus tropicalis 36144 R-XTR-9707504 https://reactome.org/PathwayBrowser/#/R-XTR-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Xenopus tropicalis 36144 R-XTR-9707516 https://reactome.org/PathwayBrowser/#/R-XTR-9707516 FeHM dissociates from MetHb IEA Xenopus tropicalis 36144 R-XTR-9707523 https://reactome.org/PathwayBrowser/#/R-XTR-9707523 Hemes bind to BACH1:MAFK IEA Xenopus tropicalis 36144 R-XTR-9709360 https://reactome.org/PathwayBrowser/#/R-XTR-9709360 H2O2 reduces MetHb IEA Xenopus tropicalis 36190 R-BTA-2161794 https://reactome.org/PathwayBrowser/#/R-BTA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Bos taurus 36190 R-BTA-8942208 https://reactome.org/PathwayBrowser/#/R-BTA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Bos taurus 36190 R-CFA-2161794 https://reactome.org/PathwayBrowser/#/R-CFA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Canis familiaris 36190 R-CFA-8942208 https://reactome.org/PathwayBrowser/#/R-CFA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Canis familiaris 36190 R-DDI-2161794 https://reactome.org/PathwayBrowser/#/R-DDI-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Dictyostelium discoideum 36190 R-DDI-8942208 https://reactome.org/PathwayBrowser/#/R-DDI-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Dictyostelium discoideum 36190 R-DRE-2161794 https://reactome.org/PathwayBrowser/#/R-DRE-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Danio rerio 36190 R-DRE-8942208 https://reactome.org/PathwayBrowser/#/R-DRE-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Danio rerio 36190 R-GGA-8942208 https://reactome.org/PathwayBrowser/#/R-GGA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Gallus gallus 36190 R-HSA-2161794 https://reactome.org/PathwayBrowser/#/R-HSA-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 TAS Homo sapiens 36190 R-HSA-2161949 https://reactome.org/PathwayBrowser/#/R-HSA-2161949 HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH TAS Homo sapiens 36190 R-HSA-8942208 https://reactome.org/PathwayBrowser/#/R-HSA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 TAS Homo sapiens 36190 R-MMU-2161794 https://reactome.org/PathwayBrowser/#/R-MMU-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Mus musculus 36190 R-MMU-8942208 https://reactome.org/PathwayBrowser/#/R-MMU-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Mus musculus 36190 R-RNO-2161794 https://reactome.org/PathwayBrowser/#/R-RNO-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Rattus norvegicus 36190 R-RNO-8942208 https://reactome.org/PathwayBrowser/#/R-RNO-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Rattus norvegicus 36190 R-SSC-2161794 https://reactome.org/PathwayBrowser/#/R-SSC-2161794 Arachidonic acid is converted to HXA3/B3 by ALOX12 IEA Sus scrofa 36190 R-SSC-8942208 https://reactome.org/PathwayBrowser/#/R-SSC-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Sus scrofa 36190 R-XTR-8942208 https://reactome.org/PathwayBrowser/#/R-XTR-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Xenopus tropicalis 36234 R-BTA-159425 https://reactome.org/PathwayBrowser/#/R-BTA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 36234 R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 36234 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 36234 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 36234 R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 36234 R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 36234 R-BTA-192430 https://reactome.org/PathwayBrowser/#/R-BTA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 36234 R-BTA-194121 https://reactome.org/PathwayBrowser/#/R-BTA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Bos taurus 36234 R-BTA-194130 https://reactome.org/PathwayBrowser/#/R-BTA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Bos taurus 36234 R-BTA-194153 https://reactome.org/PathwayBrowser/#/R-BTA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Bos taurus 36234 R-BTA-194187 https://reactome.org/PathwayBrowser/#/R-BTA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Bos taurus 36234 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 36234 R-BTA-444654 https://reactome.org/PathwayBrowser/#/R-BTA-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Bos taurus 36234 R-BTA-4755419 https://reactome.org/PathwayBrowser/#/R-BTA-4755419 SUMOylation of NR1H4 with SUMO1 IEA Bos taurus 36234 R-BTA-5340195 https://reactome.org/PathwayBrowser/#/R-BTA-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Bos taurus 36234 R-BTA-5340251 https://reactome.org/PathwayBrowser/#/R-BTA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Bos taurus 36234 R-BTA-9733545 https://reactome.org/PathwayBrowser/#/R-BTA-9733545 Bile salts and acids bind ALB IEA Bos taurus 36234 R-BTA-9733960 https://reactome.org/PathwayBrowser/#/R-BTA-9733960 Bile salts and acids dissociate from ALB IEA Bos taurus 36234 R-BTA-9733964 https://reactome.org/PathwayBrowser/#/R-BTA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Bos taurus 36234 R-BTA-9733969 https://reactome.org/PathwayBrowser/#/R-BTA-9733969 Bile salts dissociate from FABP6 IEA Bos taurus 36234 R-BTA-9733973 https://reactome.org/PathwayBrowser/#/R-BTA-9733973 Bile salts bind FABP6 IEA Bos taurus 36234 R-CEL-159425 https://reactome.org/PathwayBrowser/#/R-CEL-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 36234 R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 36234 R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 36234 R-CEL-192430 https://reactome.org/PathwayBrowser/#/R-CEL-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 36234 R-CEL-194121 https://reactome.org/PathwayBrowser/#/R-CEL-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 36234 R-CEL-194130 https://reactome.org/PathwayBrowser/#/R-CEL-194130 Transport (influx) of bile salts and acids by OATP-A IEA Caenorhabditis elegans 36234 R-CEL-194153 https://reactome.org/PathwayBrowser/#/R-CEL-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Caenorhabditis elegans 36234 R-CEL-194187 https://reactome.org/PathwayBrowser/#/R-CEL-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 36234 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 36234 R-CEL-444654 https://reactome.org/PathwayBrowser/#/R-CEL-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Caenorhabditis elegans 36234 R-CEL-9733969 https://reactome.org/PathwayBrowser/#/R-CEL-9733969 Bile salts dissociate from FABP6 IEA Caenorhabditis elegans 36234 R-CEL-9733973 https://reactome.org/PathwayBrowser/#/R-CEL-9733973 Bile salts bind FABP6 IEA Caenorhabditis elegans 36234 R-CFA-159425 https://reactome.org/PathwayBrowser/#/R-CFA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 36234 R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 36234 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 36234 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 36234 R-CFA-194121 https://reactome.org/PathwayBrowser/#/R-CFA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Canis familiaris 36234 R-CFA-194130 https://reactome.org/PathwayBrowser/#/R-CFA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Canis familiaris 36234 R-CFA-194153 https://reactome.org/PathwayBrowser/#/R-CFA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Canis familiaris 36234 R-CFA-194187 https://reactome.org/PathwayBrowser/#/R-CFA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Canis familiaris 36234 R-CFA-444654 https://reactome.org/PathwayBrowser/#/R-CFA-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Canis familiaris 36234 R-CFA-5340195 https://reactome.org/PathwayBrowser/#/R-CFA-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Canis familiaris 36234 R-CFA-5340251 https://reactome.org/PathwayBrowser/#/R-CFA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Canis familiaris 36234 R-CFA-9733545 https://reactome.org/PathwayBrowser/#/R-CFA-9733545 Bile salts and acids bind ALB IEA Canis familiaris 36234 R-CFA-9733960 https://reactome.org/PathwayBrowser/#/R-CFA-9733960 Bile salts and acids dissociate from ALB IEA Canis familiaris 36234 R-CFA-9733964 https://reactome.org/PathwayBrowser/#/R-CFA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Canis familiaris 36234 R-DDI-194153 https://reactome.org/PathwayBrowser/#/R-DDI-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 36234 R-DME-159425 https://reactome.org/PathwayBrowser/#/R-DME-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 36234 R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 36234 R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 36234 R-DME-192430 https://reactome.org/PathwayBrowser/#/R-DME-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 36234 R-DME-194121 https://reactome.org/PathwayBrowser/#/R-DME-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 36234 R-DME-194130 https://reactome.org/PathwayBrowser/#/R-DME-194130 Transport (influx) of bile salts and acids by OATP-A IEA Drosophila melanogaster 36234 R-DME-194153 https://reactome.org/PathwayBrowser/#/R-DME-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Drosophila melanogaster 36234 R-DME-194187 https://reactome.org/PathwayBrowser/#/R-DME-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 36234 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 36234 R-DME-444654 https://reactome.org/PathwayBrowser/#/R-DME-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Drosophila melanogaster 36234 R-DME-5340195 https://reactome.org/PathwayBrowser/#/R-DME-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Drosophila melanogaster 36234 R-DME-5340251 https://reactome.org/PathwayBrowser/#/R-DME-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Drosophila melanogaster 36234 R-DME-9733969 https://reactome.org/PathwayBrowser/#/R-DME-9733969 Bile salts dissociate from FABP6 IEA Drosophila melanogaster 36234 R-DME-9733973 https://reactome.org/PathwayBrowser/#/R-DME-9733973 Bile salts bind FABP6 IEA Drosophila melanogaster 36234 R-DRE-159425 https://reactome.org/PathwayBrowser/#/R-DRE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 36234 R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 36234 R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 36234 R-DRE-192430 https://reactome.org/PathwayBrowser/#/R-DRE-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 36234 R-DRE-194121 https://reactome.org/PathwayBrowser/#/R-DRE-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Danio rerio 36234 R-DRE-194130 https://reactome.org/PathwayBrowser/#/R-DRE-194130 Transport (influx) of bile salts and acids by OATP-A IEA Danio rerio 36234 R-DRE-194187 https://reactome.org/PathwayBrowser/#/R-DRE-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Danio rerio 36234 R-DRE-4755419 https://reactome.org/PathwayBrowser/#/R-DRE-4755419 SUMOylation of NR1H4 with SUMO1 IEA Danio rerio 36234 R-DRE-5340195 https://reactome.org/PathwayBrowser/#/R-DRE-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Danio rerio 36234 R-DRE-9733969 https://reactome.org/PathwayBrowser/#/R-DRE-9733969 Bile salts dissociate from FABP6 IEA Danio rerio 36234 R-DRE-9733973 https://reactome.org/PathwayBrowser/#/R-DRE-9733973 Bile salts bind FABP6 IEA Danio rerio 36234 R-GGA-159425 https://reactome.org/PathwayBrowser/#/R-GGA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 36234 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 36234 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 36234 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 36234 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 36234 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 36234 R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 36234 R-GGA-194130 https://reactome.org/PathwayBrowser/#/R-GGA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Gallus gallus 36234 R-GGA-194153 https://reactome.org/PathwayBrowser/#/R-GGA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Gallus gallus 36234 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus 36234 R-GGA-4755419 https://reactome.org/PathwayBrowser/#/R-GGA-4755419 SUMOylation of NR1H4 with SUMO1 IEA Gallus gallus 36234 R-GGA-5340195 https://reactome.org/PathwayBrowser/#/R-GGA-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Gallus gallus 36234 R-GGA-5340251 https://reactome.org/PathwayBrowser/#/R-GGA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Gallus gallus 36234 R-GGA-9733545 https://reactome.org/PathwayBrowser/#/R-GGA-9733545 Bile salts and acids bind ALB IEA Gallus gallus 36234 R-GGA-9733960 https://reactome.org/PathwayBrowser/#/R-GGA-9733960 Bile salts and acids dissociate from ALB IEA Gallus gallus 36234 R-GGA-9733964 https://reactome.org/PathwayBrowser/#/R-GGA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Gallus gallus 36234 R-GGA-9733969 https://reactome.org/PathwayBrowser/#/R-GGA-9733969 Bile salts dissociate from FABP6 IEA Gallus gallus 36234 R-GGA-9733973 https://reactome.org/PathwayBrowser/#/R-GGA-9733973 Bile salts bind FABP6 IEA Gallus gallus 36234 R-HSA-159425 https://reactome.org/PathwayBrowser/#/R-HSA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 36234 R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 36234 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 36234 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 36234 R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 36234 R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 36234 R-HSA-192430 https://reactome.org/PathwayBrowser/#/R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 36234 R-HSA-194121 https://reactome.org/PathwayBrowser/#/R-HSA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol TAS Homo sapiens 36234 R-HSA-194130 https://reactome.org/PathwayBrowser/#/R-HSA-194130 Transport (influx) of bile salts and acids by OATP-A TAS Homo sapiens 36234 R-HSA-194153 https://reactome.org/PathwayBrowser/#/R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region TAS Homo sapiens 36234 R-HSA-194187 https://reactome.org/PathwayBrowser/#/R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol TAS Homo sapiens 36234 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 36234 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 36234 R-HSA-444654 https://reactome.org/PathwayBrowser/#/R-HSA-444654 G-protein coupled bile acid receptor binds lithocholic acid TAS Homo sapiens 36234 R-HSA-4755419 https://reactome.org/PathwayBrowser/#/R-HSA-4755419 SUMOylation of NR1H4 with SUMO1 TAS Homo sapiens 36234 R-HSA-5340195 https://reactome.org/PathwayBrowser/#/R-HSA-5340195 NR1H4 binds DCA, CDCA, LCHA TAS Homo sapiens 36234 R-HSA-5340251 https://reactome.org/PathwayBrowser/#/R-HSA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 TAS Homo sapiens 36234 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 36234 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 36234 R-HSA-9733545 https://reactome.org/PathwayBrowser/#/R-HSA-9733545 Bile salts and acids bind ALB TAS Homo sapiens 36234 R-HSA-9733960 https://reactome.org/PathwayBrowser/#/R-HSA-9733960 Bile salts and acids dissociate from ALB TAS Homo sapiens 36234 R-HSA-9733964 https://reactome.org/PathwayBrowser/#/R-HSA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region TAS Homo sapiens 36234 R-HSA-9733969 https://reactome.org/PathwayBrowser/#/R-HSA-9733969 Bile salts dissociate from FABP6 TAS Homo sapiens 36234 R-HSA-9733973 https://reactome.org/PathwayBrowser/#/R-HSA-9733973 Bile salts bind FABP6 TAS Homo sapiens 36234 R-MMU-159425 https://reactome.org/PathwayBrowser/#/R-MMU-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 36234 R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 36234 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 36234 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 36234 R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 36234 R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 36234 R-MMU-192430 https://reactome.org/PathwayBrowser/#/R-MMU-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 36234 R-MMU-194121 https://reactome.org/PathwayBrowser/#/R-MMU-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Mus musculus 36234 R-MMU-194130 https://reactome.org/PathwayBrowser/#/R-MMU-194130 Transport (influx) of bile salts and acids by OATP-A IEA Mus musculus 36234 R-MMU-194153 https://reactome.org/PathwayBrowser/#/R-MMU-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Mus musculus 36234 R-MMU-194187 https://reactome.org/PathwayBrowser/#/R-MMU-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Mus musculus 36234 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 36234 R-MMU-444654 https://reactome.org/PathwayBrowser/#/R-MMU-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Mus musculus 36234 R-MMU-4755419 https://reactome.org/PathwayBrowser/#/R-MMU-4755419 SUMOylation of NR1H4 with SUMO1 IEA Mus musculus 36234 R-MMU-5340195 https://reactome.org/PathwayBrowser/#/R-MMU-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Mus musculus 36234 R-MMU-5340251 https://reactome.org/PathwayBrowser/#/R-MMU-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Mus musculus 36234 R-MMU-9733545 https://reactome.org/PathwayBrowser/#/R-MMU-9733545 Bile salts and acids bind ALB IEA Mus musculus 36234 R-MMU-9733960 https://reactome.org/PathwayBrowser/#/R-MMU-9733960 Bile salts and acids dissociate from ALB IEA Mus musculus 36234 R-MMU-9733964 https://reactome.org/PathwayBrowser/#/R-MMU-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Mus musculus 36234 R-MMU-9733969 https://reactome.org/PathwayBrowser/#/R-MMU-9733969 Bile salts dissociate from FABP6 IEA Mus musculus 36234 R-MMU-9733973 https://reactome.org/PathwayBrowser/#/R-MMU-9733973 Bile salts bind FABP6 IEA Mus musculus 36234 R-RNO-159425 https://reactome.org/PathwayBrowser/#/R-RNO-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 36234 R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 36234 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 36234 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 36234 R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 36234 R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 36234 R-RNO-192430 https://reactome.org/PathwayBrowser/#/R-RNO-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 36234 R-RNO-194121 https://reactome.org/PathwayBrowser/#/R-RNO-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Rattus norvegicus 36234 R-RNO-194130 https://reactome.org/PathwayBrowser/#/R-RNO-194130 Transport (influx) of bile salts and acids by OATP-A IEA Rattus norvegicus 36234 R-RNO-194153 https://reactome.org/PathwayBrowser/#/R-RNO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 36234 R-RNO-194187 https://reactome.org/PathwayBrowser/#/R-RNO-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Rattus norvegicus 36234 R-RNO-444654 https://reactome.org/PathwayBrowser/#/R-RNO-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Rattus norvegicus 36234 R-RNO-4755419 https://reactome.org/PathwayBrowser/#/R-RNO-4755419 SUMOylation of NR1H4 with SUMO1 IEA Rattus norvegicus 36234 R-RNO-5340195 https://reactome.org/PathwayBrowser/#/R-RNO-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Rattus norvegicus 36234 R-RNO-5340251 https://reactome.org/PathwayBrowser/#/R-RNO-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Rattus norvegicus 36234 R-RNO-9733545 https://reactome.org/PathwayBrowser/#/R-RNO-9733545 Bile salts and acids bind ALB IEA Rattus norvegicus 36234 R-RNO-9733960 https://reactome.org/PathwayBrowser/#/R-RNO-9733960 Bile salts and acids dissociate from ALB IEA Rattus norvegicus 36234 R-RNO-9733964 https://reactome.org/PathwayBrowser/#/R-RNO-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 36234 R-RNO-9733969 https://reactome.org/PathwayBrowser/#/R-RNO-9733969 Bile salts dissociate from FABP6 IEA Rattus norvegicus 36234 R-RNO-9733973 https://reactome.org/PathwayBrowser/#/R-RNO-9733973 Bile salts bind FABP6 IEA Rattus norvegicus 36234 R-SCE-159425 https://reactome.org/PathwayBrowser/#/R-SCE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 36234 R-SCE-194153 https://reactome.org/PathwayBrowser/#/R-SCE-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Saccharomyces cerevisiae 36234 R-SPO-194153 https://reactome.org/PathwayBrowser/#/R-SPO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 36234 R-SSC-159425 https://reactome.org/PathwayBrowser/#/R-SSC-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 36234 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 36234 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 36234 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 36234 R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 36234 R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 36234 R-SSC-192430 https://reactome.org/PathwayBrowser/#/R-SSC-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 36234 R-SSC-194121 https://reactome.org/PathwayBrowser/#/R-SSC-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Sus scrofa 36234 R-SSC-194130 https://reactome.org/PathwayBrowser/#/R-SSC-194130 Transport (influx) of bile salts and acids by OATP-A IEA Sus scrofa 36234 R-SSC-194153 https://reactome.org/PathwayBrowser/#/R-SSC-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Sus scrofa 36234 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa 36234 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 36234 R-SSC-444654 https://reactome.org/PathwayBrowser/#/R-SSC-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Sus scrofa 36234 R-SSC-4755419 https://reactome.org/PathwayBrowser/#/R-SSC-4755419 SUMOylation of NR1H4 with SUMO1 IEA Sus scrofa 36234 R-SSC-5340195 https://reactome.org/PathwayBrowser/#/R-SSC-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Sus scrofa 36234 R-SSC-5340251 https://reactome.org/PathwayBrowser/#/R-SSC-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Sus scrofa 36234 R-SSC-9733545 https://reactome.org/PathwayBrowser/#/R-SSC-9733545 Bile salts and acids bind ALB IEA Sus scrofa 36234 R-SSC-9733960 https://reactome.org/PathwayBrowser/#/R-SSC-9733960 Bile salts and acids dissociate from ALB IEA Sus scrofa 36234 R-SSC-9733964 https://reactome.org/PathwayBrowser/#/R-SSC-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Sus scrofa 36234 R-SSC-9733969 https://reactome.org/PathwayBrowser/#/R-SSC-9733969 Bile salts dissociate from FABP6 IEA Sus scrofa 36234 R-SSC-9733973 https://reactome.org/PathwayBrowser/#/R-SSC-9733973 Bile salts bind FABP6 IEA Sus scrofa 36234 R-XTR-159425 https://reactome.org/PathwayBrowser/#/R-XTR-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 36234 R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 36234 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 36234 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 36234 R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 36234 R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 36234 R-XTR-192430 https://reactome.org/PathwayBrowser/#/R-XTR-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 36234 R-XTR-194121 https://reactome.org/PathwayBrowser/#/R-XTR-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 36234 R-XTR-194153 https://reactome.org/PathwayBrowser/#/R-XTR-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 36234 R-XTR-194187 https://reactome.org/PathwayBrowser/#/R-XTR-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 36234 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 36234 R-XTR-444654 https://reactome.org/PathwayBrowser/#/R-XTR-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Xenopus tropicalis 36234 R-XTR-4755419 https://reactome.org/PathwayBrowser/#/R-XTR-4755419 SUMOylation of NR1H4 with SUMO1 IEA Xenopus tropicalis 36234 R-XTR-5340195 https://reactome.org/PathwayBrowser/#/R-XTR-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Xenopus tropicalis 36234 R-XTR-9733545 https://reactome.org/PathwayBrowser/#/R-XTR-9733545 Bile salts and acids bind ALB IEA Xenopus tropicalis 36234 R-XTR-9733960 https://reactome.org/PathwayBrowser/#/R-XTR-9733960 Bile salts and acids dissociate from ALB IEA Xenopus tropicalis 36234 R-XTR-9733964 https://reactome.org/PathwayBrowser/#/R-XTR-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 36234 R-XTR-9733969 https://reactome.org/PathwayBrowser/#/R-XTR-9733969 Bile salts dissociate from FABP6 IEA Xenopus tropicalis 36234 R-XTR-9733973 https://reactome.org/PathwayBrowser/#/R-XTR-9733973 Bile salts bind FABP6 IEA Xenopus tropicalis 36242 R-BTA-517444 https://reactome.org/PathwayBrowser/#/R-BTA-517444 TAT aminates HPP IEA Bos taurus 36242 R-BTA-71155 https://reactome.org/PathwayBrowser/#/R-BTA-71155 TAT deaminates tyrosine IEA Bos taurus 36242 R-BTA-71163 https://reactome.org/PathwayBrowser/#/R-BTA-71163 HPD dioxygenates HPP IEA Bos taurus 36242 R-CEL-517444 https://reactome.org/PathwayBrowser/#/R-CEL-517444 TAT aminates HPP IEA Caenorhabditis elegans 36242 R-CEL-71155 https://reactome.org/PathwayBrowser/#/R-CEL-71155 TAT deaminates tyrosine IEA Caenorhabditis elegans 36242 R-CEL-71163 https://reactome.org/PathwayBrowser/#/R-CEL-71163 HPD dioxygenates HPP IEA Caenorhabditis elegans 36242 R-CFA-517444 https://reactome.org/PathwayBrowser/#/R-CFA-517444 TAT aminates HPP IEA Canis familiaris 36242 R-CFA-71155 https://reactome.org/PathwayBrowser/#/R-CFA-71155 TAT deaminates tyrosine IEA Canis familiaris 36242 R-CFA-71163 https://reactome.org/PathwayBrowser/#/R-CFA-71163 HPD dioxygenates HPP IEA Canis familiaris 36242 R-DDI-517444 https://reactome.org/PathwayBrowser/#/R-DDI-517444 TAT aminates HPP IEA Dictyostelium discoideum 36242 R-DDI-71155 https://reactome.org/PathwayBrowser/#/R-DDI-71155 TAT deaminates tyrosine IEA Dictyostelium discoideum 36242 R-DDI-71163 https://reactome.org/PathwayBrowser/#/R-DDI-71163 HPD dioxygenates HPP IEA Dictyostelium discoideum 36242 R-DME-517444 https://reactome.org/PathwayBrowser/#/R-DME-517444 TAT aminates HPP IEA Drosophila melanogaster 36242 R-DME-71155 https://reactome.org/PathwayBrowser/#/R-DME-71155 TAT deaminates tyrosine IEA Drosophila melanogaster 36242 R-DME-71163 https://reactome.org/PathwayBrowser/#/R-DME-71163 HPD dioxygenates HPP IEA Drosophila melanogaster 36242 R-DRE-517444 https://reactome.org/PathwayBrowser/#/R-DRE-517444 TAT aminates HPP IEA Danio rerio 36242 R-DRE-71155 https://reactome.org/PathwayBrowser/#/R-DRE-71155 TAT deaminates tyrosine IEA Danio rerio 36242 R-DRE-71163 https://reactome.org/PathwayBrowser/#/R-DRE-71163 HPD dioxygenates HPP IEA Danio rerio 36242 R-GGA-517444 https://reactome.org/PathwayBrowser/#/R-GGA-517444 TAT aminates HPP IEA Gallus gallus 36242 R-GGA-71155 https://reactome.org/PathwayBrowser/#/R-GGA-71155 TAT deaminates tyrosine IEA Gallus gallus 36242 R-GGA-71163 https://reactome.org/PathwayBrowser/#/R-GGA-71163 HPD dioxygenates HPP IEA Gallus gallus 36242 R-HSA-517444 https://reactome.org/PathwayBrowser/#/R-HSA-517444 TAT aminates HPP TAS Homo sapiens 36242 R-HSA-71155 https://reactome.org/PathwayBrowser/#/R-HSA-71155 TAT deaminates tyrosine TAS Homo sapiens 36242 R-HSA-71163 https://reactome.org/PathwayBrowser/#/R-HSA-71163 HPD dioxygenates HPP TAS Homo sapiens 36242 R-MMU-517444 https://reactome.org/PathwayBrowser/#/R-MMU-517444 TAT aminates HPP IEA Mus musculus 36242 R-MMU-71155 https://reactome.org/PathwayBrowser/#/R-MMU-71155 TAT deaminates tyrosine IEA Mus musculus 36242 R-MMU-71163 https://reactome.org/PathwayBrowser/#/R-MMU-71163 HPD dioxygenates HPP IEA Mus musculus 36242 R-RNO-517444 https://reactome.org/PathwayBrowser/#/R-RNO-517444 TAT aminates HPP IEA Rattus norvegicus 36242 R-RNO-71155 https://reactome.org/PathwayBrowser/#/R-RNO-71155 TAT deaminates tyrosine IEA Rattus norvegicus 36242 R-RNO-71163 https://reactome.org/PathwayBrowser/#/R-RNO-71163 HPD dioxygenates HPP IEA Rattus norvegicus 36242 R-SSC-517444 https://reactome.org/PathwayBrowser/#/R-SSC-517444 TAT aminates HPP IEA Sus scrofa 36242 R-SSC-71155 https://reactome.org/PathwayBrowser/#/R-SSC-71155 TAT deaminates tyrosine IEA Sus scrofa 36242 R-SSC-71163 https://reactome.org/PathwayBrowser/#/R-SSC-71163 HPD dioxygenates HPP IEA Sus scrofa 36242 R-XTR-517444 https://reactome.org/PathwayBrowser/#/R-XTR-517444 TAT aminates HPP IEA Xenopus tropicalis 36242 R-XTR-71155 https://reactome.org/PathwayBrowser/#/R-XTR-71155 TAT deaminates tyrosine IEA Xenopus tropicalis 36242 R-XTR-71163 https://reactome.org/PathwayBrowser/#/R-XTR-71163 HPD dioxygenates HPP IEA Xenopus tropicalis 36252 R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 36252 R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 36252 R-BTA-192430 https://reactome.org/PathwayBrowser/#/R-BTA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 36252 R-BTA-193362 https://reactome.org/PathwayBrowser/#/R-BTA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Bos taurus 36252 R-BTA-194121 https://reactome.org/PathwayBrowser/#/R-BTA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Bos taurus 36252 R-BTA-194130 https://reactome.org/PathwayBrowser/#/R-BTA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Bos taurus 36252 R-BTA-194153 https://reactome.org/PathwayBrowser/#/R-BTA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Bos taurus 36252 R-BTA-194187 https://reactome.org/PathwayBrowser/#/R-BTA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Bos taurus 36252 R-BTA-9733545 https://reactome.org/PathwayBrowser/#/R-BTA-9733545 Bile salts and acids bind ALB IEA Bos taurus 36252 R-BTA-9733960 https://reactome.org/PathwayBrowser/#/R-BTA-9733960 Bile salts and acids dissociate from ALB IEA Bos taurus 36252 R-BTA-9733964 https://reactome.org/PathwayBrowser/#/R-BTA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Bos taurus 36252 R-BTA-9733969 https://reactome.org/PathwayBrowser/#/R-BTA-9733969 Bile salts dissociate from FABP6 IEA Bos taurus 36252 R-BTA-9733973 https://reactome.org/PathwayBrowser/#/R-BTA-9733973 Bile salts bind FABP6 IEA Bos taurus 36252 R-CEL-159431 https://reactome.org/PathwayBrowser/#/R-CEL-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Caenorhabditis elegans 36252 R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 36252 R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 36252 R-CEL-192430 https://reactome.org/PathwayBrowser/#/R-CEL-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 36252 R-CEL-193491 https://reactome.org/PathwayBrowser/#/R-CEL-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Caenorhabditis elegans 36252 R-CEL-194121 https://reactome.org/PathwayBrowser/#/R-CEL-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 36252 R-CEL-194130 https://reactome.org/PathwayBrowser/#/R-CEL-194130 Transport (influx) of bile salts and acids by OATP-A IEA Caenorhabditis elegans 36252 R-CEL-194153 https://reactome.org/PathwayBrowser/#/R-CEL-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Caenorhabditis elegans 36252 R-CEL-194187 https://reactome.org/PathwayBrowser/#/R-CEL-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 36252 R-CEL-9733969 https://reactome.org/PathwayBrowser/#/R-CEL-9733969 Bile salts dissociate from FABP6 IEA Caenorhabditis elegans 36252 R-CEL-9733973 https://reactome.org/PathwayBrowser/#/R-CEL-9733973 Bile salts bind FABP6 IEA Caenorhabditis elegans 36252 R-CFA-159431 https://reactome.org/PathwayBrowser/#/R-CFA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Canis familiaris 36252 R-CFA-193362 https://reactome.org/PathwayBrowser/#/R-CFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Canis familiaris 36252 R-CFA-193491 https://reactome.org/PathwayBrowser/#/R-CFA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Canis familiaris 36252 R-CFA-194121 https://reactome.org/PathwayBrowser/#/R-CFA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Canis familiaris 36252 R-CFA-194130 https://reactome.org/PathwayBrowser/#/R-CFA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Canis familiaris 36252 R-CFA-194153 https://reactome.org/PathwayBrowser/#/R-CFA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Canis familiaris 36252 R-CFA-194187 https://reactome.org/PathwayBrowser/#/R-CFA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Canis familiaris 36252 R-CFA-9733545 https://reactome.org/PathwayBrowser/#/R-CFA-9733545 Bile salts and acids bind ALB IEA Canis familiaris 36252 R-CFA-9733960 https://reactome.org/PathwayBrowser/#/R-CFA-9733960 Bile salts and acids dissociate from ALB IEA Canis familiaris 36252 R-CFA-9733964 https://reactome.org/PathwayBrowser/#/R-CFA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Canis familiaris 36252 R-DDI-193362 https://reactome.org/PathwayBrowser/#/R-DDI-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 36252 R-DDI-194153 https://reactome.org/PathwayBrowser/#/R-DDI-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 36252 R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 36252 R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 36252 R-DME-192430 https://reactome.org/PathwayBrowser/#/R-DME-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 36252 R-DME-194121 https://reactome.org/PathwayBrowser/#/R-DME-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 36252 R-DME-194130 https://reactome.org/PathwayBrowser/#/R-DME-194130 Transport (influx) of bile salts and acids by OATP-A IEA Drosophila melanogaster 36252 R-DME-194153 https://reactome.org/PathwayBrowser/#/R-DME-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Drosophila melanogaster 36252 R-DME-194187 https://reactome.org/PathwayBrowser/#/R-DME-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 36252 R-DME-9733969 https://reactome.org/PathwayBrowser/#/R-DME-9733969 Bile salts dissociate from FABP6 IEA Drosophila melanogaster 36252 R-DME-9733973 https://reactome.org/PathwayBrowser/#/R-DME-9733973 Bile salts bind FABP6 IEA Drosophila melanogaster 36252 R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 36252 R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 36252 R-DRE-192430 https://reactome.org/PathwayBrowser/#/R-DRE-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 36252 R-DRE-194121 https://reactome.org/PathwayBrowser/#/R-DRE-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Danio rerio 36252 R-DRE-194130 https://reactome.org/PathwayBrowser/#/R-DRE-194130 Transport (influx) of bile salts and acids by OATP-A IEA Danio rerio 36252 R-DRE-194187 https://reactome.org/PathwayBrowser/#/R-DRE-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Danio rerio 36252 R-DRE-9733969 https://reactome.org/PathwayBrowser/#/R-DRE-9733969 Bile salts dissociate from FABP6 IEA Danio rerio 36252 R-DRE-9733973 https://reactome.org/PathwayBrowser/#/R-DRE-9733973 Bile salts bind FABP6 IEA Danio rerio 36252 R-GGA-159431 https://reactome.org/PathwayBrowser/#/R-GGA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Gallus gallus 36252 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 36252 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 36252 R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 36252 R-GGA-193362 https://reactome.org/PathwayBrowser/#/R-GGA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Gallus gallus 36252 R-GGA-193491 https://reactome.org/PathwayBrowser/#/R-GGA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Gallus gallus 36252 R-GGA-194130 https://reactome.org/PathwayBrowser/#/R-GGA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Gallus gallus 36252 R-GGA-194153 https://reactome.org/PathwayBrowser/#/R-GGA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Gallus gallus 36252 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus 36252 R-GGA-9733545 https://reactome.org/PathwayBrowser/#/R-GGA-9733545 Bile salts and acids bind ALB IEA Gallus gallus 36252 R-GGA-9733960 https://reactome.org/PathwayBrowser/#/R-GGA-9733960 Bile salts and acids dissociate from ALB IEA Gallus gallus 36252 R-GGA-9733964 https://reactome.org/PathwayBrowser/#/R-GGA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Gallus gallus 36252 R-GGA-9733969 https://reactome.org/PathwayBrowser/#/R-GGA-9733969 Bile salts dissociate from FABP6 IEA Gallus gallus 36252 R-GGA-9733973 https://reactome.org/PathwayBrowser/#/R-GGA-9733973 Bile salts bind FABP6 IEA Gallus gallus 36252 R-HSA-159431 https://reactome.org/PathwayBrowser/#/R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine TAS Homo sapiens 36252 R-HSA-192315 https://reactome.org/PathwayBrowser/#/R-HSA-192315 Bile salts are translocated from the peroxisomal matrix to the cytosol TAS Homo sapiens 36252 R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 36252 R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 36252 R-HSA-192430 https://reactome.org/PathwayBrowser/#/R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 36252 R-HSA-193362 https://reactome.org/PathwayBrowser/#/R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region TAS Homo sapiens 36252 R-HSA-193491 https://reactome.org/PathwayBrowser/#/R-HSA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate TAS Homo sapiens 36252 R-HSA-194121 https://reactome.org/PathwayBrowser/#/R-HSA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol TAS Homo sapiens 36252 R-HSA-194130 https://reactome.org/PathwayBrowser/#/R-HSA-194130 Transport (influx) of bile salts and acids by OATP-A TAS Homo sapiens 36252 R-HSA-194153 https://reactome.org/PathwayBrowser/#/R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region TAS Homo sapiens 36252 R-HSA-194187 https://reactome.org/PathwayBrowser/#/R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol TAS Homo sapiens 36252 R-HSA-5678517 https://reactome.org/PathwayBrowser/#/R-HSA-5678517 Defective ABCB11 does not transport bile salts from cytosol to extracellular region TAS Homo sapiens 36252 R-HSA-9733545 https://reactome.org/PathwayBrowser/#/R-HSA-9733545 Bile salts and acids bind ALB TAS Homo sapiens 36252 R-HSA-9733960 https://reactome.org/PathwayBrowser/#/R-HSA-9733960 Bile salts and acids dissociate from ALB TAS Homo sapiens 36252 R-HSA-9733964 https://reactome.org/PathwayBrowser/#/R-HSA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region TAS Homo sapiens 36252 R-HSA-9733969 https://reactome.org/PathwayBrowser/#/R-HSA-9733969 Bile salts dissociate from FABP6 TAS Homo sapiens 36252 R-HSA-9733973 https://reactome.org/PathwayBrowser/#/R-HSA-9733973 Bile salts bind FABP6 TAS Homo sapiens 36252 R-MMU-159431 https://reactome.org/PathwayBrowser/#/R-MMU-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Mus musculus 36252 R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 36252 R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 36252 R-MMU-192430 https://reactome.org/PathwayBrowser/#/R-MMU-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 36252 R-MMU-193362 https://reactome.org/PathwayBrowser/#/R-MMU-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Mus musculus 36252 R-MMU-193491 https://reactome.org/PathwayBrowser/#/R-MMU-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Mus musculus 36252 R-MMU-194121 https://reactome.org/PathwayBrowser/#/R-MMU-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Mus musculus 36252 R-MMU-194130 https://reactome.org/PathwayBrowser/#/R-MMU-194130 Transport (influx) of bile salts and acids by OATP-A IEA Mus musculus 36252 R-MMU-194153 https://reactome.org/PathwayBrowser/#/R-MMU-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Mus musculus 36252 R-MMU-194187 https://reactome.org/PathwayBrowser/#/R-MMU-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Mus musculus 36252 R-MMU-9733545 https://reactome.org/PathwayBrowser/#/R-MMU-9733545 Bile salts and acids bind ALB IEA Mus musculus 36252 R-MMU-9733960 https://reactome.org/PathwayBrowser/#/R-MMU-9733960 Bile salts and acids dissociate from ALB IEA Mus musculus 36252 R-MMU-9733964 https://reactome.org/PathwayBrowser/#/R-MMU-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Mus musculus 36252 R-MMU-9733969 https://reactome.org/PathwayBrowser/#/R-MMU-9733969 Bile salts dissociate from FABP6 IEA Mus musculus 36252 R-MMU-9733973 https://reactome.org/PathwayBrowser/#/R-MMU-9733973 Bile salts bind FABP6 IEA Mus musculus 36252 R-PFA-193362 https://reactome.org/PathwayBrowser/#/R-PFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Plasmodium falciparum 36252 R-RNO-159431 https://reactome.org/PathwayBrowser/#/R-RNO-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Rattus norvegicus 36252 R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 36252 R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 36252 R-RNO-192430 https://reactome.org/PathwayBrowser/#/R-RNO-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 36252 R-RNO-193362 https://reactome.org/PathwayBrowser/#/R-RNO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 36252 R-RNO-193491 https://reactome.org/PathwayBrowser/#/R-RNO-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Rattus norvegicus 36252 R-RNO-194121 https://reactome.org/PathwayBrowser/#/R-RNO-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Rattus norvegicus 36252 R-RNO-194130 https://reactome.org/PathwayBrowser/#/R-RNO-194130 Transport (influx) of bile salts and acids by OATP-A IEA Rattus norvegicus 36252 R-RNO-194153 https://reactome.org/PathwayBrowser/#/R-RNO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 36252 R-RNO-194187 https://reactome.org/PathwayBrowser/#/R-RNO-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Rattus norvegicus 36252 R-RNO-9733545 https://reactome.org/PathwayBrowser/#/R-RNO-9733545 Bile salts and acids bind ALB IEA Rattus norvegicus 36252 R-RNO-9733960 https://reactome.org/PathwayBrowser/#/R-RNO-9733960 Bile salts and acids dissociate from ALB IEA Rattus norvegicus 36252 R-RNO-9733964 https://reactome.org/PathwayBrowser/#/R-RNO-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 36252 R-RNO-9733969 https://reactome.org/PathwayBrowser/#/R-RNO-9733969 Bile salts dissociate from FABP6 IEA Rattus norvegicus 36252 R-RNO-9733973 https://reactome.org/PathwayBrowser/#/R-RNO-9733973 Bile salts bind FABP6 IEA Rattus norvegicus 36252 R-SCE-194153 https://reactome.org/PathwayBrowser/#/R-SCE-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Saccharomyces cerevisiae 36252 R-SPO-193362 https://reactome.org/PathwayBrowser/#/R-SPO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 36252 R-SPO-194153 https://reactome.org/PathwayBrowser/#/R-SPO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 36252 R-SSC-159431 https://reactome.org/PathwayBrowser/#/R-SSC-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Sus scrofa 36252 R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 36252 R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 36252 R-SSC-192430 https://reactome.org/PathwayBrowser/#/R-SSC-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 36252 R-SSC-193362 https://reactome.org/PathwayBrowser/#/R-SSC-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Sus scrofa 36252 R-SSC-193491 https://reactome.org/PathwayBrowser/#/R-SSC-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Sus scrofa 36252 R-SSC-194121 https://reactome.org/PathwayBrowser/#/R-SSC-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Sus scrofa 36252 R-SSC-194130 https://reactome.org/PathwayBrowser/#/R-SSC-194130 Transport (influx) of bile salts and acids by OATP-A IEA Sus scrofa 36252 R-SSC-194153 https://reactome.org/PathwayBrowser/#/R-SSC-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Sus scrofa 36252 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa 36252 R-SSC-9733545 https://reactome.org/PathwayBrowser/#/R-SSC-9733545 Bile salts and acids bind ALB IEA Sus scrofa 36252 R-SSC-9733960 https://reactome.org/PathwayBrowser/#/R-SSC-9733960 Bile salts and acids dissociate from ALB IEA Sus scrofa 36252 R-SSC-9733964 https://reactome.org/PathwayBrowser/#/R-SSC-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Sus scrofa 36252 R-SSC-9733969 https://reactome.org/PathwayBrowser/#/R-SSC-9733969 Bile salts dissociate from FABP6 IEA Sus scrofa 36252 R-SSC-9733973 https://reactome.org/PathwayBrowser/#/R-SSC-9733973 Bile salts bind FABP6 IEA Sus scrofa 36252 R-XTR-159431 https://reactome.org/PathwayBrowser/#/R-XTR-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Xenopus tropicalis 36252 R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 36252 R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 36252 R-XTR-192430 https://reactome.org/PathwayBrowser/#/R-XTR-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 36252 R-XTR-193491 https://reactome.org/PathwayBrowser/#/R-XTR-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Xenopus tropicalis 36252 R-XTR-194121 https://reactome.org/PathwayBrowser/#/R-XTR-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 36252 R-XTR-194153 https://reactome.org/PathwayBrowser/#/R-XTR-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 36252 R-XTR-194187 https://reactome.org/PathwayBrowser/#/R-XTR-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 36252 R-XTR-9733545 https://reactome.org/PathwayBrowser/#/R-XTR-9733545 Bile salts and acids bind ALB IEA Xenopus tropicalis 36252 R-XTR-9733960 https://reactome.org/PathwayBrowser/#/R-XTR-9733960 Bile salts and acids dissociate from ALB IEA Xenopus tropicalis 36252 R-XTR-9733964 https://reactome.org/PathwayBrowser/#/R-XTR-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 36252 R-XTR-9733969 https://reactome.org/PathwayBrowser/#/R-XTR-9733969 Bile salts dissociate from FABP6 IEA Xenopus tropicalis 36252 R-XTR-9733973 https://reactome.org/PathwayBrowser/#/R-XTR-9733973 Bile salts bind FABP6 IEA Xenopus tropicalis 36257 R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 36257 R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 36257 R-BTA-192430 https://reactome.org/PathwayBrowser/#/R-BTA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 36257 R-BTA-193362 https://reactome.org/PathwayBrowser/#/R-BTA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Bos taurus 36257 R-BTA-194079 https://reactome.org/PathwayBrowser/#/R-BTA-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Bos taurus 36257 R-BTA-194083 https://reactome.org/PathwayBrowser/#/R-BTA-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Bos taurus 36257 R-BTA-194121 https://reactome.org/PathwayBrowser/#/R-BTA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Bos taurus 36257 R-BTA-194130 https://reactome.org/PathwayBrowser/#/R-BTA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Bos taurus 36257 R-BTA-194153 https://reactome.org/PathwayBrowser/#/R-BTA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Bos taurus 36257 R-BTA-194187 https://reactome.org/PathwayBrowser/#/R-BTA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Bos taurus 36257 R-BTA-9733545 https://reactome.org/PathwayBrowser/#/R-BTA-9733545 Bile salts and acids bind ALB IEA Bos taurus 36257 R-BTA-9733960 https://reactome.org/PathwayBrowser/#/R-BTA-9733960 Bile salts and acids dissociate from ALB IEA Bos taurus 36257 R-BTA-9733964 https://reactome.org/PathwayBrowser/#/R-BTA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Bos taurus 36257 R-BTA-9733969 https://reactome.org/PathwayBrowser/#/R-BTA-9733969 Bile salts dissociate from FABP6 IEA Bos taurus 36257 R-BTA-9733973 https://reactome.org/PathwayBrowser/#/R-BTA-9733973 Bile salts bind FABP6 IEA Bos taurus 36257 R-CEL-159431 https://reactome.org/PathwayBrowser/#/R-CEL-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Caenorhabditis elegans 36257 R-CEL-192312 https://reactome.org/PathwayBrowser/#/R-CEL-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Caenorhabditis elegans 36257 R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 36257 R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 36257 R-CEL-192430 https://reactome.org/PathwayBrowser/#/R-CEL-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 36257 R-CEL-194079 https://reactome.org/PathwayBrowser/#/R-CEL-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Caenorhabditis elegans 36257 R-CEL-194083 https://reactome.org/PathwayBrowser/#/R-CEL-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Caenorhabditis elegans 36257 R-CEL-194121 https://reactome.org/PathwayBrowser/#/R-CEL-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 36257 R-CEL-194130 https://reactome.org/PathwayBrowser/#/R-CEL-194130 Transport (influx) of bile salts and acids by OATP-A IEA Caenorhabditis elegans 36257 R-CEL-194153 https://reactome.org/PathwayBrowser/#/R-CEL-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Caenorhabditis elegans 36257 R-CEL-194187 https://reactome.org/PathwayBrowser/#/R-CEL-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 36257 R-CEL-9733969 https://reactome.org/PathwayBrowser/#/R-CEL-9733969 Bile salts dissociate from FABP6 IEA Caenorhabditis elegans 36257 R-CEL-9733973 https://reactome.org/PathwayBrowser/#/R-CEL-9733973 Bile salts bind FABP6 IEA Caenorhabditis elegans 36257 R-CFA-159431 https://reactome.org/PathwayBrowser/#/R-CFA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Canis familiaris 36257 R-CFA-192312 https://reactome.org/PathwayBrowser/#/R-CFA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Canis familiaris 36257 R-CFA-193362 https://reactome.org/PathwayBrowser/#/R-CFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Canis familiaris 36257 R-CFA-194079 https://reactome.org/PathwayBrowser/#/R-CFA-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Canis familiaris 36257 R-CFA-194083 https://reactome.org/PathwayBrowser/#/R-CFA-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Canis familiaris 36257 R-CFA-194121 https://reactome.org/PathwayBrowser/#/R-CFA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Canis familiaris 36257 R-CFA-194130 https://reactome.org/PathwayBrowser/#/R-CFA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Canis familiaris 36257 R-CFA-194153 https://reactome.org/PathwayBrowser/#/R-CFA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Canis familiaris 36257 R-CFA-194187 https://reactome.org/PathwayBrowser/#/R-CFA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Canis familiaris 36257 R-CFA-9733545 https://reactome.org/PathwayBrowser/#/R-CFA-9733545 Bile salts and acids bind ALB IEA Canis familiaris 36257 R-CFA-9733960 https://reactome.org/PathwayBrowser/#/R-CFA-9733960 Bile salts and acids dissociate from ALB IEA Canis familiaris 36257 R-CFA-9733964 https://reactome.org/PathwayBrowser/#/R-CFA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Canis familiaris 36257 R-DDI-193362 https://reactome.org/PathwayBrowser/#/R-DDI-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 36257 R-DDI-194153 https://reactome.org/PathwayBrowser/#/R-DDI-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 36257 R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 36257 R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 36257 R-DME-192430 https://reactome.org/PathwayBrowser/#/R-DME-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 36257 R-DME-194079 https://reactome.org/PathwayBrowser/#/R-DME-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Drosophila melanogaster 36257 R-DME-194083 https://reactome.org/PathwayBrowser/#/R-DME-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Drosophila melanogaster 36257 R-DME-194121 https://reactome.org/PathwayBrowser/#/R-DME-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 36257 R-DME-194130 https://reactome.org/PathwayBrowser/#/R-DME-194130 Transport (influx) of bile salts and acids by OATP-A IEA Drosophila melanogaster 36257 R-DME-194153 https://reactome.org/PathwayBrowser/#/R-DME-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Drosophila melanogaster 36257 R-DME-194187 https://reactome.org/PathwayBrowser/#/R-DME-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 36257 R-DME-9733969 https://reactome.org/PathwayBrowser/#/R-DME-9733969 Bile salts dissociate from FABP6 IEA Drosophila melanogaster 36257 R-DME-9733973 https://reactome.org/PathwayBrowser/#/R-DME-9733973 Bile salts bind FABP6 IEA Drosophila melanogaster 36257 R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 36257 R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 36257 R-DRE-192430 https://reactome.org/PathwayBrowser/#/R-DRE-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 36257 R-DRE-194079 https://reactome.org/PathwayBrowser/#/R-DRE-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Danio rerio 36257 R-DRE-194083 https://reactome.org/PathwayBrowser/#/R-DRE-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Danio rerio 36257 R-DRE-194121 https://reactome.org/PathwayBrowser/#/R-DRE-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Danio rerio 36257 R-DRE-194130 https://reactome.org/PathwayBrowser/#/R-DRE-194130 Transport (influx) of bile salts and acids by OATP-A IEA Danio rerio 36257 R-DRE-194187 https://reactome.org/PathwayBrowser/#/R-DRE-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Danio rerio 36257 R-DRE-9733969 https://reactome.org/PathwayBrowser/#/R-DRE-9733969 Bile salts dissociate from FABP6 IEA Danio rerio 36257 R-DRE-9733973 https://reactome.org/PathwayBrowser/#/R-DRE-9733973 Bile salts bind FABP6 IEA Danio rerio 36257 R-GGA-159431 https://reactome.org/PathwayBrowser/#/R-GGA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Gallus gallus 36257 R-GGA-192312 https://reactome.org/PathwayBrowser/#/R-GGA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Gallus gallus 36257 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 36257 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 36257 R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 36257 R-GGA-193362 https://reactome.org/PathwayBrowser/#/R-GGA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Gallus gallus 36257 R-GGA-194079 https://reactome.org/PathwayBrowser/#/R-GGA-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Gallus gallus 36257 R-GGA-194083 https://reactome.org/PathwayBrowser/#/R-GGA-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Gallus gallus 36257 R-GGA-194130 https://reactome.org/PathwayBrowser/#/R-GGA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Gallus gallus 36257 R-GGA-194153 https://reactome.org/PathwayBrowser/#/R-GGA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Gallus gallus 36257 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus 36257 R-GGA-9733545 https://reactome.org/PathwayBrowser/#/R-GGA-9733545 Bile salts and acids bind ALB IEA Gallus gallus 36257 R-GGA-9733960 https://reactome.org/PathwayBrowser/#/R-GGA-9733960 Bile salts and acids dissociate from ALB IEA Gallus gallus 36257 R-GGA-9733964 https://reactome.org/PathwayBrowser/#/R-GGA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Gallus gallus 36257 R-GGA-9733969 https://reactome.org/PathwayBrowser/#/R-GGA-9733969 Bile salts dissociate from FABP6 IEA Gallus gallus 36257 R-GGA-9733973 https://reactome.org/PathwayBrowser/#/R-GGA-9733973 Bile salts bind FABP6 IEA Gallus gallus 36257 R-HSA-159431 https://reactome.org/PathwayBrowser/#/R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine TAS Homo sapiens 36257 R-HSA-192312 https://reactome.org/PathwayBrowser/#/R-HSA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate TAS Homo sapiens 36257 R-HSA-192315 https://reactome.org/PathwayBrowser/#/R-HSA-192315 Bile salts are translocated from the peroxisomal matrix to the cytosol TAS Homo sapiens 36257 R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 36257 R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 36257 R-HSA-192430 https://reactome.org/PathwayBrowser/#/R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 36257 R-HSA-193362 https://reactome.org/PathwayBrowser/#/R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region TAS Homo sapiens 36257 R-HSA-194079 https://reactome.org/PathwayBrowser/#/R-HSA-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol TAS Homo sapiens 36257 R-HSA-194083 https://reactome.org/PathwayBrowser/#/R-HSA-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol TAS Homo sapiens 36257 R-HSA-194121 https://reactome.org/PathwayBrowser/#/R-HSA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol TAS Homo sapiens 36257 R-HSA-194130 https://reactome.org/PathwayBrowser/#/R-HSA-194130 Transport (influx) of bile salts and acids by OATP-A TAS Homo sapiens 36257 R-HSA-194153 https://reactome.org/PathwayBrowser/#/R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region TAS Homo sapiens 36257 R-HSA-194187 https://reactome.org/PathwayBrowser/#/R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol TAS Homo sapiens 36257 R-HSA-5678517 https://reactome.org/PathwayBrowser/#/R-HSA-5678517 Defective ABCB11 does not transport bile salts from cytosol to extracellular region TAS Homo sapiens 36257 R-HSA-9733545 https://reactome.org/PathwayBrowser/#/R-HSA-9733545 Bile salts and acids bind ALB TAS Homo sapiens 36257 R-HSA-9733960 https://reactome.org/PathwayBrowser/#/R-HSA-9733960 Bile salts and acids dissociate from ALB TAS Homo sapiens 36257 R-HSA-9733964 https://reactome.org/PathwayBrowser/#/R-HSA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region TAS Homo sapiens 36257 R-HSA-9733969 https://reactome.org/PathwayBrowser/#/R-HSA-9733969 Bile salts dissociate from FABP6 TAS Homo sapiens 36257 R-HSA-9733973 https://reactome.org/PathwayBrowser/#/R-HSA-9733973 Bile salts bind FABP6 TAS Homo sapiens 36257 R-MMU-159431 https://reactome.org/PathwayBrowser/#/R-MMU-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Mus musculus 36257 R-MMU-192312 https://reactome.org/PathwayBrowser/#/R-MMU-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Mus musculus 36257 R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 36257 R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 36257 R-MMU-192430 https://reactome.org/PathwayBrowser/#/R-MMU-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 36257 R-MMU-193362 https://reactome.org/PathwayBrowser/#/R-MMU-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Mus musculus 36257 R-MMU-194079 https://reactome.org/PathwayBrowser/#/R-MMU-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Mus musculus 36257 R-MMU-194083 https://reactome.org/PathwayBrowser/#/R-MMU-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Mus musculus 36257 R-MMU-194121 https://reactome.org/PathwayBrowser/#/R-MMU-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Mus musculus 36257 R-MMU-194130 https://reactome.org/PathwayBrowser/#/R-MMU-194130 Transport (influx) of bile salts and acids by OATP-A IEA Mus musculus 36257 R-MMU-194153 https://reactome.org/PathwayBrowser/#/R-MMU-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Mus musculus 36257 R-MMU-194187 https://reactome.org/PathwayBrowser/#/R-MMU-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Mus musculus 36257 R-MMU-9733545 https://reactome.org/PathwayBrowser/#/R-MMU-9733545 Bile salts and acids bind ALB IEA Mus musculus 36257 R-MMU-9733960 https://reactome.org/PathwayBrowser/#/R-MMU-9733960 Bile salts and acids dissociate from ALB IEA Mus musculus 36257 R-MMU-9733964 https://reactome.org/PathwayBrowser/#/R-MMU-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Mus musculus 36257 R-MMU-9733969 https://reactome.org/PathwayBrowser/#/R-MMU-9733969 Bile salts dissociate from FABP6 IEA Mus musculus 36257 R-MMU-9733973 https://reactome.org/PathwayBrowser/#/R-MMU-9733973 Bile salts bind FABP6 IEA Mus musculus 36257 R-PFA-193362 https://reactome.org/PathwayBrowser/#/R-PFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Plasmodium falciparum 36257 R-RNO-159431 https://reactome.org/PathwayBrowser/#/R-RNO-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Rattus norvegicus 36257 R-RNO-192312 https://reactome.org/PathwayBrowser/#/R-RNO-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Rattus norvegicus 36257 R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 36257 R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 36257 R-RNO-192430 https://reactome.org/PathwayBrowser/#/R-RNO-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 36257 R-RNO-193362 https://reactome.org/PathwayBrowser/#/R-RNO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 36257 R-RNO-194079 https://reactome.org/PathwayBrowser/#/R-RNO-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Rattus norvegicus 36257 R-RNO-194083 https://reactome.org/PathwayBrowser/#/R-RNO-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Rattus norvegicus 36257 R-RNO-194121 https://reactome.org/PathwayBrowser/#/R-RNO-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Rattus norvegicus 36257 R-RNO-194130 https://reactome.org/PathwayBrowser/#/R-RNO-194130 Transport (influx) of bile salts and acids by OATP-A IEA Rattus norvegicus 36257 R-RNO-194153 https://reactome.org/PathwayBrowser/#/R-RNO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 36257 R-RNO-194187 https://reactome.org/PathwayBrowser/#/R-RNO-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Rattus norvegicus 36257 R-RNO-9733545 https://reactome.org/PathwayBrowser/#/R-RNO-9733545 Bile salts and acids bind ALB IEA Rattus norvegicus 36257 R-RNO-9733960 https://reactome.org/PathwayBrowser/#/R-RNO-9733960 Bile salts and acids dissociate from ALB IEA Rattus norvegicus 36257 R-RNO-9733964 https://reactome.org/PathwayBrowser/#/R-RNO-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 36257 R-RNO-9733969 https://reactome.org/PathwayBrowser/#/R-RNO-9733969 Bile salts dissociate from FABP6 IEA Rattus norvegicus 36257 R-RNO-9733973 https://reactome.org/PathwayBrowser/#/R-RNO-9733973 Bile salts bind FABP6 IEA Rattus norvegicus 36257 R-SCE-194153 https://reactome.org/PathwayBrowser/#/R-SCE-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Saccharomyces cerevisiae 36257 R-SPO-193362 https://reactome.org/PathwayBrowser/#/R-SPO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 36257 R-SPO-194153 https://reactome.org/PathwayBrowser/#/R-SPO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 36257 R-SSC-159431 https://reactome.org/PathwayBrowser/#/R-SSC-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Sus scrofa 36257 R-SSC-192312 https://reactome.org/PathwayBrowser/#/R-SSC-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Sus scrofa 36257 R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 36257 R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 36257 R-SSC-192430 https://reactome.org/PathwayBrowser/#/R-SSC-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 36257 R-SSC-193362 https://reactome.org/PathwayBrowser/#/R-SSC-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Sus scrofa 36257 R-SSC-194079 https://reactome.org/PathwayBrowser/#/R-SSC-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Sus scrofa 36257 R-SSC-194083 https://reactome.org/PathwayBrowser/#/R-SSC-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Sus scrofa 36257 R-SSC-194121 https://reactome.org/PathwayBrowser/#/R-SSC-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Sus scrofa 36257 R-SSC-194130 https://reactome.org/PathwayBrowser/#/R-SSC-194130 Transport (influx) of bile salts and acids by OATP-A IEA Sus scrofa 36257 R-SSC-194153 https://reactome.org/PathwayBrowser/#/R-SSC-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Sus scrofa 36257 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa 36257 R-SSC-9733545 https://reactome.org/PathwayBrowser/#/R-SSC-9733545 Bile salts and acids bind ALB IEA Sus scrofa 36257 R-SSC-9733960 https://reactome.org/PathwayBrowser/#/R-SSC-9733960 Bile salts and acids dissociate from ALB IEA Sus scrofa 36257 R-SSC-9733964 https://reactome.org/PathwayBrowser/#/R-SSC-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Sus scrofa 36257 R-SSC-9733969 https://reactome.org/PathwayBrowser/#/R-SSC-9733969 Bile salts dissociate from FABP6 IEA Sus scrofa 36257 R-SSC-9733973 https://reactome.org/PathwayBrowser/#/R-SSC-9733973 Bile salts bind FABP6 IEA Sus scrofa 36257 R-XTR-159431 https://reactome.org/PathwayBrowser/#/R-XTR-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Xenopus tropicalis 36257 R-XTR-192312 https://reactome.org/PathwayBrowser/#/R-XTR-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Xenopus tropicalis 36257 R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 36257 R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 36257 R-XTR-192430 https://reactome.org/PathwayBrowser/#/R-XTR-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 36257 R-XTR-194079 https://reactome.org/PathwayBrowser/#/R-XTR-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Xenopus tropicalis 36257 R-XTR-194083 https://reactome.org/PathwayBrowser/#/R-XTR-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Xenopus tropicalis 36257 R-XTR-194121 https://reactome.org/PathwayBrowser/#/R-XTR-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 36257 R-XTR-194153 https://reactome.org/PathwayBrowser/#/R-XTR-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 36257 R-XTR-194187 https://reactome.org/PathwayBrowser/#/R-XTR-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 36257 R-XTR-9733545 https://reactome.org/PathwayBrowser/#/R-XTR-9733545 Bile salts and acids bind ALB IEA Xenopus tropicalis 36257 R-XTR-9733960 https://reactome.org/PathwayBrowser/#/R-XTR-9733960 Bile salts and acids dissociate from ALB IEA Xenopus tropicalis 36257 R-XTR-9733964 https://reactome.org/PathwayBrowser/#/R-XTR-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 36257 R-XTR-9733969 https://reactome.org/PathwayBrowser/#/R-XTR-9733969 Bile salts dissociate from FABP6 IEA Xenopus tropicalis 36257 R-XTR-9733973 https://reactome.org/PathwayBrowser/#/R-XTR-9733973 Bile salts bind FABP6 IEA Xenopus tropicalis 36264 R-BTA-947531 https://reactome.org/PathwayBrowser/#/R-BTA-947531 Molybdenum ion transfer onto molybdopterin IEA Bos taurus 36264 R-CEL-947531 https://reactome.org/PathwayBrowser/#/R-CEL-947531 Molybdenum ion transfer onto molybdopterin IEA Caenorhabditis elegans 36264 R-CFA-947531 https://reactome.org/PathwayBrowser/#/R-CFA-947531 Molybdenum ion transfer onto molybdopterin IEA Canis familiaris 36264 R-DDI-947531 https://reactome.org/PathwayBrowser/#/R-DDI-947531 Molybdenum ion transfer onto molybdopterin IEA Dictyostelium discoideum 36264 R-DME-947531 https://reactome.org/PathwayBrowser/#/R-DME-947531 Molybdenum ion transfer onto molybdopterin IEA Drosophila melanogaster 36264 R-GGA-947531 https://reactome.org/PathwayBrowser/#/R-GGA-947531 Molybdenum ion transfer onto molybdopterin IEA Gallus gallus 36264 R-HSA-947531 https://reactome.org/PathwayBrowser/#/R-HSA-947531 Molybdenum ion transfer onto molybdopterin TAS Homo sapiens 36264 R-MMU-947531 https://reactome.org/PathwayBrowser/#/R-MMU-947531 Molybdenum ion transfer onto molybdopterin IEA Mus musculus 36264 R-RNO-947531 https://reactome.org/PathwayBrowser/#/R-RNO-947531 Molybdenum ion transfer onto molybdopterin IEA Rattus norvegicus 36264 R-SSC-947531 https://reactome.org/PathwayBrowser/#/R-SSC-947531 Molybdenum ion transfer onto molybdopterin IEA Sus scrofa 36313 R-BTA-8874435 https://reactome.org/PathwayBrowser/#/R-BTA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Bos taurus 36313 R-CEL-8874435 https://reactome.org/PathwayBrowser/#/R-CEL-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Caenorhabditis elegans 36313 R-CFA-8874435 https://reactome.org/PathwayBrowser/#/R-CFA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Canis familiaris 36313 R-DDI-8874435 https://reactome.org/PathwayBrowser/#/R-DDI-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Dictyostelium discoideum 36313 R-DME-8874435 https://reactome.org/PathwayBrowser/#/R-DME-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Drosophila melanogaster 36313 R-DRE-8874435 https://reactome.org/PathwayBrowser/#/R-DRE-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Danio rerio 36313 R-HSA-8874435 https://reactome.org/PathwayBrowser/#/R-HSA-8874435 THEM86B hydrolyses PMCHO, PMETAM TAS Homo sapiens 36313 R-MMU-8874435 https://reactome.org/PathwayBrowser/#/R-MMU-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Mus musculus 36313 R-RNO-8874435 https://reactome.org/PathwayBrowser/#/R-RNO-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Rattus norvegicus 36313 R-SSC-8874435 https://reactome.org/PathwayBrowser/#/R-SSC-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Sus scrofa 36313 R-XTR-8874435 https://reactome.org/PathwayBrowser/#/R-XTR-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Xenopus tropicalis 36314 R-BTA-8874435 https://reactome.org/PathwayBrowser/#/R-BTA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Bos taurus 36314 R-CEL-8874435 https://reactome.org/PathwayBrowser/#/R-CEL-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Caenorhabditis elegans 36314 R-CFA-8874435 https://reactome.org/PathwayBrowser/#/R-CFA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Canis familiaris 36314 R-DDI-8874435 https://reactome.org/PathwayBrowser/#/R-DDI-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Dictyostelium discoideum 36314 R-DME-8874435 https://reactome.org/PathwayBrowser/#/R-DME-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Drosophila melanogaster 36314 R-DRE-8874435 https://reactome.org/PathwayBrowser/#/R-DRE-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Danio rerio 36314 R-HSA-8874435 https://reactome.org/PathwayBrowser/#/R-HSA-8874435 THEM86B hydrolyses PMCHO, PMETAM TAS Homo sapiens 36314 R-MMU-8874435 https://reactome.org/PathwayBrowser/#/R-MMU-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Mus musculus 36314 R-RNO-8874435 https://reactome.org/PathwayBrowser/#/R-RNO-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Rattus norvegicus 36314 R-SSC-8874435 https://reactome.org/PathwayBrowser/#/R-SSC-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Sus scrofa 36314 R-XTR-8874435 https://reactome.org/PathwayBrowser/#/R-XTR-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Xenopus tropicalis 36319 R-BTA-189406 https://reactome.org/PathwayBrowser/#/R-BTA-189406 4 PBGs bind to form HMB IEA Bos taurus 36319 R-CFA-189406 https://reactome.org/PathwayBrowser/#/R-CFA-189406 4 PBGs bind to form HMB IEA Canis familiaris 36319 R-DME-189406 https://reactome.org/PathwayBrowser/#/R-DME-189406 4 PBGs bind to form HMB IEA Drosophila melanogaster 36319 R-GGA-189406 https://reactome.org/PathwayBrowser/#/R-GGA-189406 4 PBGs bind to form HMB IEA Gallus gallus 36319 R-GGA-421439 https://reactome.org/PathwayBrowser/#/R-GGA-421439 4 porphobilinogen + H2O => hydroxymethylbilane + 4 NH3 IEA Gallus gallus 36319 R-HSA-189406 https://reactome.org/PathwayBrowser/#/R-HSA-189406 4 PBGs bind to form HMB TAS Homo sapiens 36319 R-MMU-189406 https://reactome.org/PathwayBrowser/#/R-MMU-189406 4 PBGs bind to form HMB IEA Mus musculus 36319 R-PFA-189406 https://reactome.org/PathwayBrowser/#/R-PFA-189406 4 PBGs bind to form HMB IEA Plasmodium falciparum 36319 R-RNO-189406 https://reactome.org/PathwayBrowser/#/R-RNO-189406 4 PBGs bind to form HMB IEA Rattus norvegicus 36319 R-SCE-189406 https://reactome.org/PathwayBrowser/#/R-SCE-189406 4 PBGs bind to form HMB IEA Saccharomyces cerevisiae 36319 R-SPO-189406 https://reactome.org/PathwayBrowser/#/R-SPO-189406 4 PBGs bind to form HMB IEA Schizosaccharomyces pombe 36319 R-SSC-189406 https://reactome.org/PathwayBrowser/#/R-SSC-189406 4 PBGs bind to form HMB IEA Sus scrofa 36319 R-XTR-189406 https://reactome.org/PathwayBrowser/#/R-XTR-189406 4 PBGs bind to form HMB IEA Xenopus tropicalis 36378 R-HSA-9661710 https://reactome.org/PathwayBrowser/#/R-HSA-9661710 An unknown oxidase oxidises D-UBGN to UBN TAS Homo sapiens 364453 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 364453 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 364453 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 364453 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 364453 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 364453 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 364453 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 364453 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 364453 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 364453 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 364453 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 364453 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 364453 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 364453 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 364453 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 364453 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 364453 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 364453 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 36464 R-BTA-191352 https://reactome.org/PathwayBrowser/#/R-BTA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Bos taurus 36464 R-BTA-191380 https://reactome.org/PathwayBrowser/#/R-BTA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Bos taurus 36464 R-CEL-191352 https://reactome.org/PathwayBrowser/#/R-CEL-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Caenorhabditis elegans 36464 R-CEL-191380 https://reactome.org/PathwayBrowser/#/R-CEL-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Caenorhabditis elegans 36464 R-CFA-191352 https://reactome.org/PathwayBrowser/#/R-CFA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Canis familiaris 36464 R-CFA-191380 https://reactome.org/PathwayBrowser/#/R-CFA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Canis familiaris 36464 R-DDI-191352 https://reactome.org/PathwayBrowser/#/R-DDI-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Dictyostelium discoideum 36464 R-DDI-191380 https://reactome.org/PathwayBrowser/#/R-DDI-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Dictyostelium discoideum 36464 R-DME-191352 https://reactome.org/PathwayBrowser/#/R-DME-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Drosophila melanogaster 36464 R-DME-191380 https://reactome.org/PathwayBrowser/#/R-DME-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Drosophila melanogaster 36464 R-DRE-191352 https://reactome.org/PathwayBrowser/#/R-DRE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Danio rerio 36464 R-DRE-191380 https://reactome.org/PathwayBrowser/#/R-DRE-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Danio rerio 36464 R-GGA-191352 https://reactome.org/PathwayBrowser/#/R-GGA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Gallus gallus 36464 R-GGA-191380 https://reactome.org/PathwayBrowser/#/R-GGA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Gallus gallus 36464 R-HSA-191352 https://reactome.org/PathwayBrowser/#/R-HSA-191352 HMGCR dimer reduces bHMG-CoA to MVA TAS Homo sapiens 36464 R-HSA-191380 https://reactome.org/PathwayBrowser/#/R-HSA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate TAS Homo sapiens 36464 R-MMU-191352 https://reactome.org/PathwayBrowser/#/R-MMU-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Mus musculus 36464 R-MMU-191380 https://reactome.org/PathwayBrowser/#/R-MMU-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Mus musculus 36464 R-RNO-191352 https://reactome.org/PathwayBrowser/#/R-RNO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Rattus norvegicus 36464 R-RNO-191380 https://reactome.org/PathwayBrowser/#/R-RNO-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Rattus norvegicus 36464 R-SCE-191352 https://reactome.org/PathwayBrowser/#/R-SCE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Saccharomyces cerevisiae 36464 R-SCE-191380 https://reactome.org/PathwayBrowser/#/R-SCE-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Saccharomyces cerevisiae 36464 R-SPO-191352 https://reactome.org/PathwayBrowser/#/R-SPO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Schizosaccharomyces pombe 36464 R-SPO-191380 https://reactome.org/PathwayBrowser/#/R-SPO-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Schizosaccharomyces pombe 36464 R-SSC-191352 https://reactome.org/PathwayBrowser/#/R-SSC-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Sus scrofa 36464 R-SSC-191380 https://reactome.org/PathwayBrowser/#/R-SSC-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Sus scrofa 36464 R-XTR-191352 https://reactome.org/PathwayBrowser/#/R-XTR-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Xenopus tropicalis 36498 R-BTA-1606564 https://reactome.org/PathwayBrowser/#/R-BTA-1606564 GALC hydrolyzes GalCer IEA Bos taurus 36498 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 36498 R-BTA-6785933 https://reactome.org/PathwayBrowser/#/R-BTA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Bos taurus 36498 R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 36498 R-BTA-9844587 https://reactome.org/PathwayBrowser/#/R-BTA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Bos taurus 36498 R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 36498 R-BTA-9844955 https://reactome.org/PathwayBrowser/#/R-BTA-9844955 CLN3 transports GalCer to plasma membrane IEA Bos taurus 36498 R-CEL-1606564 https://reactome.org/PathwayBrowser/#/R-CEL-1606564 GALC hydrolyzes GalCer IEA Caenorhabditis elegans 36498 R-CEL-6785933 https://reactome.org/PathwayBrowser/#/R-CEL-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Caenorhabditis elegans 36498 R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 36498 R-CEL-9844955 https://reactome.org/PathwayBrowser/#/R-CEL-9844955 CLN3 transports GalCer to plasma membrane IEA Caenorhabditis elegans 36498 R-CFA-1606564 https://reactome.org/PathwayBrowser/#/R-CFA-1606564 GALC hydrolyzes GalCer IEA Canis familiaris 36498 R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 36498 R-CFA-6785933 https://reactome.org/PathwayBrowser/#/R-CFA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Canis familiaris 36498 R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 36498 R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 36498 R-CFA-9844955 https://reactome.org/PathwayBrowser/#/R-CFA-9844955 CLN3 transports GalCer to plasma membrane IEA Canis familiaris 36498 R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 36498 R-DME-9844955 https://reactome.org/PathwayBrowser/#/R-DME-9844955 CLN3 transports GalCer to plasma membrane IEA Drosophila melanogaster 36498 R-DRE-6785933 https://reactome.org/PathwayBrowser/#/R-DRE-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Danio rerio 36498 R-DRE-9844587 https://reactome.org/PathwayBrowser/#/R-DRE-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Danio rerio 36498 R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 36498 R-DRE-9844955 https://reactome.org/PathwayBrowser/#/R-DRE-9844955 CLN3 transports GalCer to plasma membrane IEA Danio rerio 36498 R-GGA-1606564 https://reactome.org/PathwayBrowser/#/R-GGA-1606564 GALC hydrolyzes GalCer IEA Gallus gallus 36498 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 36498 R-GGA-6785933 https://reactome.org/PathwayBrowser/#/R-GGA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Gallus gallus 36498 R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 36498 R-GGA-9844587 https://reactome.org/PathwayBrowser/#/R-GGA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Gallus gallus 36498 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 36498 R-HSA-1606564 https://reactome.org/PathwayBrowser/#/R-HSA-1606564 GALC hydrolyzes GalCer TAS Homo sapiens 36498 R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 36498 R-HSA-6785933 https://reactome.org/PathwayBrowser/#/R-HSA-6785933 UGT8 transfers Gal from UDP-Gal to CERA TAS Homo sapiens 36498 R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 36498 R-HSA-9844587 https://reactome.org/PathwayBrowser/#/R-HSA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer TAS Homo sapiens 36498 R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 36498 R-HSA-9844955 https://reactome.org/PathwayBrowser/#/R-HSA-9844955 CLN3 transports GalCer to plasma membrane TAS Homo sapiens 36498 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 36498 R-MMU-1606564 https://reactome.org/PathwayBrowser/#/R-MMU-1606564 GALC hydrolyzes GalCer IEA Mus musculus 36498 R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 36498 R-MMU-6785933 https://reactome.org/PathwayBrowser/#/R-MMU-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Mus musculus 36498 R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 36498 R-MMU-9844587 https://reactome.org/PathwayBrowser/#/R-MMU-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Mus musculus 36498 R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 36498 R-MMU-9844955 https://reactome.org/PathwayBrowser/#/R-MMU-9844955 CLN3 transports GalCer to plasma membrane IEA Mus musculus 36498 R-RNO-1606564 https://reactome.org/PathwayBrowser/#/R-RNO-1606564 GALC hydrolyzes GalCer IEA Rattus norvegicus 36498 R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 36498 R-RNO-6785933 https://reactome.org/PathwayBrowser/#/R-RNO-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Rattus norvegicus 36498 R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 36498 R-RNO-9844587 https://reactome.org/PathwayBrowser/#/R-RNO-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Rattus norvegicus 36498 R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 36498 R-RNO-9844955 https://reactome.org/PathwayBrowser/#/R-RNO-9844955 CLN3 transports GalCer to plasma membrane IEA Rattus norvegicus 36498 R-SCE-9844955 https://reactome.org/PathwayBrowser/#/R-SCE-9844955 CLN3 transports GalCer to plasma membrane IEA Saccharomyces cerevisiae 36498 R-SPO-9844955 https://reactome.org/PathwayBrowser/#/R-SPO-9844955 CLN3 transports GalCer to plasma membrane IEA Schizosaccharomyces pombe 36498 R-SSC-1606564 https://reactome.org/PathwayBrowser/#/R-SSC-1606564 GALC hydrolyzes GalCer IEA Sus scrofa 36498 R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 36498 R-SSC-6785933 https://reactome.org/PathwayBrowser/#/R-SSC-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Sus scrofa 36498 R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 36498 R-SSC-9844587 https://reactome.org/PathwayBrowser/#/R-SSC-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Sus scrofa 36498 R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 36498 R-SSC-9844955 https://reactome.org/PathwayBrowser/#/R-SSC-9844955 CLN3 transports GalCer to plasma membrane IEA Sus scrofa 36498 R-XTR-9844587 https://reactome.org/PathwayBrowser/#/R-XTR-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Xenopus tropicalis 36498 R-XTR-9844955 https://reactome.org/PathwayBrowser/#/R-XTR-9844955 CLN3 transports GalCer to plasma membrane IEA Xenopus tropicalis 3650 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 3650 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 3650 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 3650 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 3650 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 3650 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 3650 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 3650 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 3650 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 36654 R-BTA-9749986 https://reactome.org/PathwayBrowser/#/R-BTA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Bos taurus 36654 R-BTA-9750656 https://reactome.org/PathwayBrowser/#/R-BTA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Bos taurus 36654 R-CEL-9749986 https://reactome.org/PathwayBrowser/#/R-CEL-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Caenorhabditis elegans 36654 R-CEL-9750656 https://reactome.org/PathwayBrowser/#/R-CEL-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Caenorhabditis elegans 36654 R-CFA-9749986 https://reactome.org/PathwayBrowser/#/R-CFA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Canis familiaris 36654 R-CFA-9750656 https://reactome.org/PathwayBrowser/#/R-CFA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Canis familiaris 36654 R-DDI-9749986 https://reactome.org/PathwayBrowser/#/R-DDI-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Dictyostelium discoideum 36654 R-DDI-9750656 https://reactome.org/PathwayBrowser/#/R-DDI-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Dictyostelium discoideum 36654 R-DME-9749986 https://reactome.org/PathwayBrowser/#/R-DME-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Drosophila melanogaster 36654 R-DME-9750656 https://reactome.org/PathwayBrowser/#/R-DME-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Drosophila melanogaster 36654 R-DRE-9749986 https://reactome.org/PathwayBrowser/#/R-DRE-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Danio rerio 36654 R-DRE-9750656 https://reactome.org/PathwayBrowser/#/R-DRE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Danio rerio 36654 R-GGA-9749986 https://reactome.org/PathwayBrowser/#/R-GGA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Gallus gallus 36654 R-GGA-9750656 https://reactome.org/PathwayBrowser/#/R-GGA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Gallus gallus 36654 R-HSA-9749986 https://reactome.org/PathwayBrowser/#/R-HSA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA TAS Homo sapiens 36654 R-HSA-9750656 https://reactome.org/PathwayBrowser/#/R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells TAS Homo sapiens 36654 R-HSA-9757459 https://reactome.org/PathwayBrowser/#/R-HSA-9757459 ST metabolites diffuse out of ER lumen TAS Homo sapiens 36654 R-HSA-9757462 https://reactome.org/PathwayBrowser/#/R-HSA-9757462 Hydroxyl radicals oxidize ST to 2,3-DHBA TAS Homo sapiens 36654 R-MMU-9749986 https://reactome.org/PathwayBrowser/#/R-MMU-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Mus musculus 36654 R-MMU-9750656 https://reactome.org/PathwayBrowser/#/R-MMU-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Mus musculus 36654 R-RNO-9749986 https://reactome.org/PathwayBrowser/#/R-RNO-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Rattus norvegicus 36654 R-RNO-9750656 https://reactome.org/PathwayBrowser/#/R-RNO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Rattus norvegicus 36654 R-SCE-9750656 https://reactome.org/PathwayBrowser/#/R-SCE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Saccharomyces cerevisiae 36654 R-SPO-9750656 https://reactome.org/PathwayBrowser/#/R-SPO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Schizosaccharomyces pombe 36654 R-SSC-9749986 https://reactome.org/PathwayBrowser/#/R-SSC-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Sus scrofa 36654 R-SSC-9750656 https://reactome.org/PathwayBrowser/#/R-SSC-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Sus scrofa 36654 R-XTR-9749986 https://reactome.org/PathwayBrowser/#/R-XTR-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Xenopus tropicalis 36654 R-XTR-9750656 https://reactome.org/PathwayBrowser/#/R-XTR-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Xenopus tropicalis 36655 R-BTA-6784423 https://reactome.org/PathwayBrowser/#/R-BTA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Bos taurus 36655 R-BTA-904864 https://reactome.org/PathwayBrowser/#/R-BTA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Bos taurus 36655 R-CEL-904864 https://reactome.org/PathwayBrowser/#/R-CEL-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Caenorhabditis elegans 36655 R-CFA-6784423 https://reactome.org/PathwayBrowser/#/R-CFA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Canis familiaris 36655 R-CFA-904864 https://reactome.org/PathwayBrowser/#/R-CFA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Canis familiaris 36655 R-DME-904864 https://reactome.org/PathwayBrowser/#/R-DME-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Drosophila melanogaster 36655 R-DRE-6784423 https://reactome.org/PathwayBrowser/#/R-DRE-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Danio rerio 36655 R-DRE-904864 https://reactome.org/PathwayBrowser/#/R-DRE-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Danio rerio 36655 R-GGA-6784423 https://reactome.org/PathwayBrowser/#/R-GGA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Gallus gallus 36655 R-GGA-904864 https://reactome.org/PathwayBrowser/#/R-GGA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Gallus gallus 36655 R-HSA-6784423 https://reactome.org/PathwayBrowser/#/R-HSA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate TAS Homo sapiens 36655 R-HSA-6784436 https://reactome.org/PathwayBrowser/#/R-HSA-6784436 An unknown carrier transports mitochondrial glyoxylate to the cytosol TAS Homo sapiens 36655 R-HSA-904864 https://reactome.org/PathwayBrowser/#/R-HSA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate TAS Homo sapiens 36655 R-HSA-9863531 https://reactome.org/PathwayBrowser/#/R-HSA-9863531 GS-MCA spontaneously hydrolyzes TAS Homo sapiens 36655 R-MMU-6784423 https://reactome.org/PathwayBrowser/#/R-MMU-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Mus musculus 36655 R-MMU-904864 https://reactome.org/PathwayBrowser/#/R-MMU-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Mus musculus 36655 R-RNO-6784423 https://reactome.org/PathwayBrowser/#/R-RNO-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Rattus norvegicus 36655 R-RNO-904864 https://reactome.org/PathwayBrowser/#/R-RNO-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Rattus norvegicus 36655 R-SPO-904864 https://reactome.org/PathwayBrowser/#/R-SPO-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Schizosaccharomyces pombe 36655 R-SSC-6784423 https://reactome.org/PathwayBrowser/#/R-SSC-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Sus scrofa 36655 R-SSC-904864 https://reactome.org/PathwayBrowser/#/R-SSC-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Sus scrofa 36655 R-XTR-6784423 https://reactome.org/PathwayBrowser/#/R-XTR-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Xenopus tropicalis 36655 R-XTR-904864 https://reactome.org/PathwayBrowser/#/R-XTR-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Xenopus tropicalis 36700 R-BTA-1483004 https://reactome.org/PathwayBrowser/#/R-BTA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Bos taurus 36700 R-BTA-1483081 https://reactome.org/PathwayBrowser/#/R-BTA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Bos taurus 36700 R-BTA-1483159 https://reactome.org/PathwayBrowser/#/R-BTA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Bos taurus 36700 R-BTA-173626 https://reactome.org/PathwayBrowser/#/R-BTA-173626 Activation of C1r IEA Bos taurus 36700 R-CEL-1483004 https://reactome.org/PathwayBrowser/#/R-CEL-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Caenorhabditis elegans 36700 R-CEL-1483081 https://reactome.org/PathwayBrowser/#/R-CEL-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Caenorhabditis elegans 36700 R-CFA-1483004 https://reactome.org/PathwayBrowser/#/R-CFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Canis familiaris 36700 R-CFA-1483081 https://reactome.org/PathwayBrowser/#/R-CFA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Canis familiaris 36700 R-CFA-1483159 https://reactome.org/PathwayBrowser/#/R-CFA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Canis familiaris 36700 R-CFA-173626 https://reactome.org/PathwayBrowser/#/R-CFA-173626 Activation of C1r IEA Canis familiaris 36700 R-DDI-1483081 https://reactome.org/PathwayBrowser/#/R-DDI-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Dictyostelium discoideum 36700 R-DME-1483004 https://reactome.org/PathwayBrowser/#/R-DME-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Drosophila melanogaster 36700 R-DME-1483081 https://reactome.org/PathwayBrowser/#/R-DME-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Drosophila melanogaster 36700 R-DME-1483159 https://reactome.org/PathwayBrowser/#/R-DME-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Drosophila melanogaster 36700 R-DRE-1483004 https://reactome.org/PathwayBrowser/#/R-DRE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Danio rerio 36700 R-DRE-1483081 https://reactome.org/PathwayBrowser/#/R-DRE-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Danio rerio 36700 R-DRE-1483159 https://reactome.org/PathwayBrowser/#/R-DRE-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Danio rerio 36700 R-GGA-1483004 https://reactome.org/PathwayBrowser/#/R-GGA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Gallus gallus 36700 R-GGA-1483081 https://reactome.org/PathwayBrowser/#/R-GGA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Gallus gallus 36700 R-GGA-1483159 https://reactome.org/PathwayBrowser/#/R-GGA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Gallus gallus 36700 R-GGA-173626 https://reactome.org/PathwayBrowser/#/R-GGA-173626 Activation of C1r IEA Gallus gallus 36700 R-HSA-1483004 https://reactome.org/PathwayBrowser/#/R-HSA-1483004 Cho is phosphorylated to PCho by CHK dimer TAS Homo sapiens 36700 R-HSA-1483081 https://reactome.org/PathwayBrowser/#/R-HSA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer TAS Homo sapiens 36700 R-HSA-1483159 https://reactome.org/PathwayBrowser/#/R-HSA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 TAS Homo sapiens 36700 R-HSA-173626 https://reactome.org/PathwayBrowser/#/R-HSA-173626 Activation of C1r TAS Homo sapiens 36700 R-MMU-1483004 https://reactome.org/PathwayBrowser/#/R-MMU-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Mus musculus 36700 R-MMU-1483081 https://reactome.org/PathwayBrowser/#/R-MMU-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Mus musculus 36700 R-MMU-1483159 https://reactome.org/PathwayBrowser/#/R-MMU-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Mus musculus 36700 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus 36700 R-PFA-1483004 https://reactome.org/PathwayBrowser/#/R-PFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Plasmodium falciparum 36700 R-PFA-1483081 https://reactome.org/PathwayBrowser/#/R-PFA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Plasmodium falciparum 36700 R-RNO-1483004 https://reactome.org/PathwayBrowser/#/R-RNO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Rattus norvegicus 36700 R-RNO-1483081 https://reactome.org/PathwayBrowser/#/R-RNO-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Rattus norvegicus 36700 R-RNO-1483159 https://reactome.org/PathwayBrowser/#/R-RNO-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Rattus norvegicus 36700 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus 36700 R-SCE-1483004 https://reactome.org/PathwayBrowser/#/R-SCE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Saccharomyces cerevisiae 36700 R-SCE-1483081 https://reactome.org/PathwayBrowser/#/R-SCE-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Saccharomyces cerevisiae 36700 R-SPO-1483004 https://reactome.org/PathwayBrowser/#/R-SPO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Schizosaccharomyces pombe 36700 R-SPO-1483081 https://reactome.org/PathwayBrowser/#/R-SPO-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Schizosaccharomyces pombe 36700 R-SSC-1483004 https://reactome.org/PathwayBrowser/#/R-SSC-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Sus scrofa 36700 R-SSC-1483081 https://reactome.org/PathwayBrowser/#/R-SSC-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Sus scrofa 36700 R-SSC-1483159 https://reactome.org/PathwayBrowser/#/R-SSC-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Sus scrofa 36700 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa 36700 R-XTR-1483004 https://reactome.org/PathwayBrowser/#/R-XTR-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Xenopus tropicalis 36700 R-XTR-1483081 https://reactome.org/PathwayBrowser/#/R-XTR-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Xenopus tropicalis 36700 R-XTR-1483159 https://reactome.org/PathwayBrowser/#/R-XTR-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Xenopus tropicalis 36704 R-GGA-1008270 https://reactome.org/PathwayBrowser/#/R-GGA-1008270 Activated TAK1 leaves endosome membrane IEA Gallus gallus 36704 R-GGA-451439 https://reactome.org/PathwayBrowser/#/R-GGA-451439 Activated TLR7 or 21 recruits MyD88 IEA Gallus gallus 36704 R-GGA-451461 https://reactome.org/PathwayBrowser/#/R-GGA-451461 IRAK4 binds to the activated TLR7 or 21 IEA Gallus gallus 36704 R-GGA-451481 https://reactome.org/PathwayBrowser/#/R-GGA-451481 TLR7 binds to recognized ligands TAS Gallus gallus 36704 R-GGA-532630 https://reactome.org/PathwayBrowser/#/R-GGA-532630 p-IRAK2- TRAF6 dissociates from the activated TRL7 or 21 IEA Gallus gallus 36704 R-GGA-532632 https://reactome.org/PathwayBrowser/#/R-GGA-532632 TRAF6 binds to p-IRAK2 complexed with activated TLR7 or TLR21 IEA Gallus gallus 36704 R-GGA-571316 https://reactome.org/PathwayBrowser/#/R-GGA-571316 Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. IEA Gallus gallus 36704 R-GGA-571318 https://reactome.org/PathwayBrowser/#/R-GGA-571318 Autoubiquitination of oligoTRAF6 bound to p-IRAK2 IEA Gallus gallus 36704 R-GGA-571324 https://reactome.org/PathwayBrowser/#/R-GGA-571324 IRAK2 binds to p-IRAK4:MyD88:activated TLR7 or 21 complex IEA Gallus gallus 36704 R-GGA-571327 https://reactome.org/PathwayBrowser/#/R-GGA-571327 IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex IEA Gallus gallus 36704 R-GGA-573294 https://reactome.org/PathwayBrowser/#/R-GGA-573294 Activated TRAF6 synthesizes free K63 linked pUb chains. IEA Gallus gallus 36704 R-GGA-573296 https://reactome.org/PathwayBrowser/#/R-GGA-573296 Activated TRAF6 recruits TAK1 kinase complex upon TLR7 or TLR21 stimulation IEA Gallus gallus 36704 R-GGA-994000 https://reactome.org/PathwayBrowser/#/R-GGA-994000 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation IEA Gallus gallus 36704 R-HSA-167983 https://reactome.org/PathwayBrowser/#/R-HSA-167983 C-ter TLR7 dimer binds TLR7, TLR8 ligands TAS Homo sapiens 36704 R-HSA-9691204 https://reactome.org/PathwayBrowser/#/R-HSA-9691204 TLR8 dimer binds TLR7, TLR8 ligands TAS Homo sapiens 36704 R-HSA-975098 https://reactome.org/PathwayBrowser/#/R-HSA-975098 MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 TAS Homo sapiens 36704 R-HSA-975100 https://reactome.org/PathwayBrowser/#/R-HSA-975100 Dissociation of hp-IRAK1/or IRAK2:TRAF6-oligomer from the p-IRAK4 :oligo-Myd88:activated TLR7/8 or 9 complex TAS Homo sapiens 36704 R-HSA-975106 https://reactome.org/PathwayBrowser/#/R-HSA-975106 Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 36704 R-HSA-975111 https://reactome.org/PathwayBrowser/#/R-HSA-975111 TRAF6 binds to hp- IRAK1/or p-IRAK2:p-IRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 36704 R-HSA-975115 https://reactome.org/PathwayBrowser/#/R-HSA-975115 IRAK1/or IRAK2 binds to the activated IRAK4 :MyD88:activated TLR 7/8 or 9. TAS Homo sapiens 36704 R-HSA-975118 https://reactome.org/PathwayBrowser/#/R-HSA-975118 TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex TAS Homo sapiens 36704 R-HSA-975125 https://reactome.org/PathwayBrowser/#/R-HSA-975125 Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 36704 R-HSA-975134 https://reactome.org/PathwayBrowser/#/R-HSA-975134 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 TAS Homo sapiens 36704 R-HSA-975156 https://reactome.org/PathwayBrowser/#/R-HSA-975156 IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex TAS Homo sapiens 36704 R-HSA-975160 https://reactome.org/PathwayBrowser/#/R-HSA-975160 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 TAS Homo sapiens 36704 R-HSA-975170 https://reactome.org/PathwayBrowser/#/R-HSA-975170 IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 36704 R-HSA-975175 https://reactome.org/PathwayBrowser/#/R-HSA-975175 MyD88 interacts with the activated TLR receptor 7, 8 or 9 TAS Homo sapiens 36704 R-HSA-975180 https://reactome.org/PathwayBrowser/#/R-HSA-975180 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 36704 R-HSA-975188 https://reactome.org/PathwayBrowser/#/R-HSA-975188 TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 36706 R-GGA-1008270 https://reactome.org/PathwayBrowser/#/R-GGA-1008270 Activated TAK1 leaves endosome membrane IEA Gallus gallus 36706 R-GGA-451439 https://reactome.org/PathwayBrowser/#/R-GGA-451439 Activated TLR7 or 21 recruits MyD88 IEA Gallus gallus 36706 R-GGA-451461 https://reactome.org/PathwayBrowser/#/R-GGA-451461 IRAK4 binds to the activated TLR7 or 21 IEA Gallus gallus 36706 R-GGA-451481 https://reactome.org/PathwayBrowser/#/R-GGA-451481 TLR7 binds to recognized ligands TAS Gallus gallus 36706 R-GGA-532630 https://reactome.org/PathwayBrowser/#/R-GGA-532630 p-IRAK2- TRAF6 dissociates from the activated TRL7 or 21 IEA Gallus gallus 36706 R-GGA-532632 https://reactome.org/PathwayBrowser/#/R-GGA-532632 TRAF6 binds to p-IRAK2 complexed with activated TLR7 or TLR21 IEA Gallus gallus 36706 R-GGA-571316 https://reactome.org/PathwayBrowser/#/R-GGA-571316 Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. IEA Gallus gallus 36706 R-GGA-571318 https://reactome.org/PathwayBrowser/#/R-GGA-571318 Autoubiquitination of oligoTRAF6 bound to p-IRAK2 IEA Gallus gallus 36706 R-GGA-571324 https://reactome.org/PathwayBrowser/#/R-GGA-571324 IRAK2 binds to p-IRAK4:MyD88:activated TLR7 or 21 complex IEA Gallus gallus 36706 R-GGA-571327 https://reactome.org/PathwayBrowser/#/R-GGA-571327 IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex IEA Gallus gallus 36706 R-GGA-573294 https://reactome.org/PathwayBrowser/#/R-GGA-573294 Activated TRAF6 synthesizes free K63 linked pUb chains. IEA Gallus gallus 36706 R-GGA-573296 https://reactome.org/PathwayBrowser/#/R-GGA-573296 Activated TRAF6 recruits TAK1 kinase complex upon TLR7 or TLR21 stimulation IEA Gallus gallus 36706 R-GGA-994000 https://reactome.org/PathwayBrowser/#/R-GGA-994000 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation IEA Gallus gallus 36706 R-HSA-167983 https://reactome.org/PathwayBrowser/#/R-HSA-167983 C-ter TLR7 dimer binds TLR7, TLR8 ligands TAS Homo sapiens 36706 R-HSA-9691204 https://reactome.org/PathwayBrowser/#/R-HSA-9691204 TLR8 dimer binds TLR7, TLR8 ligands TAS Homo sapiens 36706 R-HSA-975098 https://reactome.org/PathwayBrowser/#/R-HSA-975098 MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 TAS Homo sapiens 36706 R-HSA-975100 https://reactome.org/PathwayBrowser/#/R-HSA-975100 Dissociation of hp-IRAK1/or IRAK2:TRAF6-oligomer from the p-IRAK4 :oligo-Myd88:activated TLR7/8 or 9 complex TAS Homo sapiens 36706 R-HSA-975106 https://reactome.org/PathwayBrowser/#/R-HSA-975106 Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 36706 R-HSA-975111 https://reactome.org/PathwayBrowser/#/R-HSA-975111 TRAF6 binds to hp- IRAK1/or p-IRAK2:p-IRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 36706 R-HSA-975115 https://reactome.org/PathwayBrowser/#/R-HSA-975115 IRAK1/or IRAK2 binds to the activated IRAK4 :MyD88:activated TLR 7/8 or 9. TAS Homo sapiens 36706 R-HSA-975118 https://reactome.org/PathwayBrowser/#/R-HSA-975118 TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex TAS Homo sapiens 36706 R-HSA-975125 https://reactome.org/PathwayBrowser/#/R-HSA-975125 Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 36706 R-HSA-975134 https://reactome.org/PathwayBrowser/#/R-HSA-975134 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 TAS Homo sapiens 36706 R-HSA-975156 https://reactome.org/PathwayBrowser/#/R-HSA-975156 IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex TAS Homo sapiens 36706 R-HSA-975160 https://reactome.org/PathwayBrowser/#/R-HSA-975160 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 TAS Homo sapiens 36706 R-HSA-975170 https://reactome.org/PathwayBrowser/#/R-HSA-975170 IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 36706 R-HSA-975175 https://reactome.org/PathwayBrowser/#/R-HSA-975175 MyD88 interacts with the activated TLR receptor 7, 8 or 9 TAS Homo sapiens 36706 R-HSA-975180 https://reactome.org/PathwayBrowser/#/R-HSA-975180 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 36706 R-HSA-975188 https://reactome.org/PathwayBrowser/#/R-HSA-975188 TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 36740 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 36740 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 36740 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 36740 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 36740 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 36740 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 36740 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 36740 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 36740 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 36773 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 36773 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 36773 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 36773 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 36773 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 36773 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 36773 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 36773 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 36773 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 36773 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 36773 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 36773 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 36773 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 36773 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 36773 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 36773 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 36773 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 36773 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 36773 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 36773 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 36773 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 36773 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 36773 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 36773 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 36773 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 36773 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 36773 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 36773 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 36773 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 36773 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 36773 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 36773 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 36773 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 36773 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 36773 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 36773 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 36773 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 36773 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 36773 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 36773 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 36773 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 36773 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 36916 R-BTA-5692480 https://reactome.org/PathwayBrowser/#/R-BTA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Bos taurus 36916 R-CFA-5692480 https://reactome.org/PathwayBrowser/#/R-CFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Canis familiaris 36916 R-DDI-5692480 https://reactome.org/PathwayBrowser/#/R-DDI-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Dictyostelium discoideum 36916 R-DRE-5692480 https://reactome.org/PathwayBrowser/#/R-DRE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Danio rerio 36916 R-GGA-5692480 https://reactome.org/PathwayBrowser/#/R-GGA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Gallus gallus 36916 R-HSA-5692480 https://reactome.org/PathwayBrowser/#/R-HSA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen TAS Homo sapiens 36916 R-MMU-5692480 https://reactome.org/PathwayBrowser/#/R-MMU-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Mus musculus 36916 R-PFA-5692480 https://reactome.org/PathwayBrowser/#/R-PFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Plasmodium falciparum 36916 R-RNO-5692480 https://reactome.org/PathwayBrowser/#/R-RNO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Rattus norvegicus 36916 R-SCE-5692480 https://reactome.org/PathwayBrowser/#/R-SCE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Saccharomyces cerevisiae 36916 R-SPO-5692480 https://reactome.org/PathwayBrowser/#/R-SPO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 36916 R-SSC-5692480 https://reactome.org/PathwayBrowser/#/R-SSC-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Sus scrofa 36916 R-XTR-5692480 https://reactome.org/PathwayBrowser/#/R-XTR-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Xenopus tropicalis 3698 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 3698 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 3698 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 3698 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 3698 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 3698 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 3698 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 3698 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 3698 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 3698 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 3698 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 3698 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 3699 R-BTA-434650 https://reactome.org/PathwayBrowser/#/R-BTA-434650 MATEs mediate extrusion of xenobiotics IEA Bos taurus 3699 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 3699 R-BTA-561041 https://reactome.org/PathwayBrowser/#/R-BTA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Bos taurus 3699 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 3699 R-BTA-9692738 https://reactome.org/PathwayBrowser/#/R-BTA-9692738 HRH2 binds HRH2 antagonists IEA Bos taurus 3699 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 3699 R-CEL-561041 https://reactome.org/PathwayBrowser/#/R-CEL-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Caenorhabditis elegans 3699 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 3699 R-CEL-9692738 https://reactome.org/PathwayBrowser/#/R-CEL-9692738 HRH2 binds HRH2 antagonists IEA Caenorhabditis elegans 3699 R-CFA-434650 https://reactome.org/PathwayBrowser/#/R-CFA-434650 MATEs mediate extrusion of xenobiotics IEA Canis familiaris 3699 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 3699 R-CFA-561041 https://reactome.org/PathwayBrowser/#/R-CFA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Canis familiaris 3699 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 3699 R-CFA-9692738 https://reactome.org/PathwayBrowser/#/R-CFA-9692738 HRH2 binds HRH2 antagonists IEA Canis familiaris 3699 R-DDI-434650 https://reactome.org/PathwayBrowser/#/R-DDI-434650 MATEs mediate extrusion of xenobiotics IEA Dictyostelium discoideum 3699 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 3699 R-DME-561041 https://reactome.org/PathwayBrowser/#/R-DME-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Drosophila melanogaster 3699 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 3699 R-DME-9692738 https://reactome.org/PathwayBrowser/#/R-DME-9692738 HRH2 binds HRH2 antagonists IEA Drosophila melanogaster 3699 R-DRE-434650 https://reactome.org/PathwayBrowser/#/R-DRE-434650 MATEs mediate extrusion of xenobiotics IEA Danio rerio 3699 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 3699 R-DRE-561041 https://reactome.org/PathwayBrowser/#/R-DRE-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Danio rerio 3699 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 3699 R-DRE-9692738 https://reactome.org/PathwayBrowser/#/R-DRE-9692738 HRH2 binds HRH2 antagonists IEA Danio rerio 3699 R-GGA-434650 https://reactome.org/PathwayBrowser/#/R-GGA-434650 MATEs mediate extrusion of xenobiotics IEA Gallus gallus 3699 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 3699 R-GGA-561041 https://reactome.org/PathwayBrowser/#/R-GGA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Gallus gallus 3699 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 3699 R-GGA-9692738 https://reactome.org/PathwayBrowser/#/R-GGA-9692738 HRH2 binds HRH2 antagonists IEA Gallus gallus 3699 R-HSA-434650 https://reactome.org/PathwayBrowser/#/R-HSA-434650 MATEs mediate extrusion of xenobiotics TAS Homo sapiens 3699 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 3699 R-HSA-561041 https://reactome.org/PathwayBrowser/#/R-HSA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids TAS Homo sapiens 3699 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 3699 R-HSA-9692738 https://reactome.org/PathwayBrowser/#/R-HSA-9692738 HRH2 binds HRH2 antagonists TAS Homo sapiens 3699 R-MMU-434650 https://reactome.org/PathwayBrowser/#/R-MMU-434650 MATEs mediate extrusion of xenobiotics IEA Mus musculus 3699 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 3699 R-MMU-561041 https://reactome.org/PathwayBrowser/#/R-MMU-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Mus musculus 3699 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 3699 R-MMU-9692738 https://reactome.org/PathwayBrowser/#/R-MMU-9692738 HRH2 binds HRH2 antagonists IEA Mus musculus 3699 R-PFA-434650 https://reactome.org/PathwayBrowser/#/R-PFA-434650 MATEs mediate extrusion of xenobiotics IEA Plasmodium falciparum 3699 R-RNO-434650 https://reactome.org/PathwayBrowser/#/R-RNO-434650 MATEs mediate extrusion of xenobiotics IEA Rattus norvegicus 3699 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 3699 R-RNO-561041 https://reactome.org/PathwayBrowser/#/R-RNO-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Rattus norvegicus 3699 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 3699 R-RNO-9692738 https://reactome.org/PathwayBrowser/#/R-RNO-9692738 HRH2 binds HRH2 antagonists IEA Rattus norvegicus 3699 R-SCE-434650 https://reactome.org/PathwayBrowser/#/R-SCE-434650 MATEs mediate extrusion of xenobiotics IEA Saccharomyces cerevisiae 3699 R-SPO-434650 https://reactome.org/PathwayBrowser/#/R-SPO-434650 MATEs mediate extrusion of xenobiotics IEA Schizosaccharomyces pombe 3699 R-SSC-434650 https://reactome.org/PathwayBrowser/#/R-SSC-434650 MATEs mediate extrusion of xenobiotics IEA Sus scrofa 3699 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 3699 R-SSC-561041 https://reactome.org/PathwayBrowser/#/R-SSC-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Sus scrofa 3699 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 3699 R-SSC-9692738 https://reactome.org/PathwayBrowser/#/R-SSC-9692738 HRH2 binds HRH2 antagonists IEA Sus scrofa 3699 R-XTR-434650 https://reactome.org/PathwayBrowser/#/R-XTR-434650 MATEs mediate extrusion of xenobiotics IEA Xenopus tropicalis 3699 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 3699 R-XTR-561041 https://reactome.org/PathwayBrowser/#/R-XTR-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Xenopus tropicalis 3699 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 3699 R-XTR-9692738 https://reactome.org/PathwayBrowser/#/R-XTR-9692738 HRH2 binds HRH2 antagonists IEA Xenopus tropicalis 37054 R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 37054 R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 37054 R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 37054 R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 37054 R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 37054 R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 37054 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 37054 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 37054 R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 37054 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 37054 R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 37054 R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 37054 R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 37054 R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 37054 R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 37054 R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 37054 R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 37054 R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 37054 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 37054 R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 37054 R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 37076 R-HSA-9697084 https://reactome.org/PathwayBrowser/#/R-HSA-9697084 Defective rpoB in Mtb RNAP transcribes RNA polyanion TAS Homo sapiens 37076 R-HSA-9697085 https://reactome.org/PathwayBrowser/#/R-HSA-9697085 RNAP transcribes Mtb RNA polyanion TAS Homo sapiens 37098 R-BTA-3296309 https://reactome.org/PathwayBrowser/#/R-BTA-3296309 HCAR3 binds HCAR3 ligands IEA Bos taurus 37098 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 37098 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 37098 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 37098 R-CFA-3296309 https://reactome.org/PathwayBrowser/#/R-CFA-3296309 HCAR3 binds HCAR3 ligands IEA Canis familiaris 37098 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 37098 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 37098 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 37098 R-DRE-3296309 https://reactome.org/PathwayBrowser/#/R-DRE-3296309 HCAR3 binds HCAR3 ligands IEA Danio rerio 37098 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 37098 R-HSA-3296309 https://reactome.org/PathwayBrowser/#/R-HSA-3296309 HCAR3 binds HCAR3 ligands TAS Homo sapiens 37098 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 37098 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 37098 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 37098 R-MMU-3296309 https://reactome.org/PathwayBrowser/#/R-MMU-3296309 HCAR3 binds HCAR3 ligands IEA Mus musculus 37098 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 37098 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 37098 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 37098 R-RNO-3296309 https://reactome.org/PathwayBrowser/#/R-RNO-3296309 HCAR3 binds HCAR3 ligands IEA Rattus norvegicus 37098 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 37098 R-SSC-3296309 https://reactome.org/PathwayBrowser/#/R-SSC-3296309 HCAR3 binds HCAR3 ligands IEA Sus scrofa 37098 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 37098 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 37098 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 37240 R-BTA-6810474 https://reactome.org/PathwayBrowser/#/R-BTA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Bos taurus 37240 R-CEL-6810474 https://reactome.org/PathwayBrowser/#/R-CEL-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Caenorhabditis elegans 37240 R-CFA-6810474 https://reactome.org/PathwayBrowser/#/R-CFA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Canis familiaris 37240 R-DDI-6810474 https://reactome.org/PathwayBrowser/#/R-DDI-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Dictyostelium discoideum 37240 R-DME-6810474 https://reactome.org/PathwayBrowser/#/R-DME-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Drosophila melanogaster 37240 R-DRE-6810474 https://reactome.org/PathwayBrowser/#/R-DRE-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Danio rerio 37240 R-GGA-6810474 https://reactome.org/PathwayBrowser/#/R-GGA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Gallus gallus 37240 R-HSA-6809354 https://reactome.org/PathwayBrowser/#/R-HSA-6809354 NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT IEA Homo sapiens 37240 R-HSA-6810474 https://reactome.org/PathwayBrowser/#/R-HSA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT TAS Homo sapiens 37240 R-MMU-6810452 https://reactome.org/PathwayBrowser/#/R-MMU-6810452 Nudt7 hydrolyses CoA-SH to 3',5'-ADP and PPANT TAS Mus musculus 37240 R-MMU-6810474 https://reactome.org/PathwayBrowser/#/R-MMU-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Mus musculus 37240 R-RNO-6810474 https://reactome.org/PathwayBrowser/#/R-RNO-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Rattus norvegicus 37240 R-SSC-6810474 https://reactome.org/PathwayBrowser/#/R-SSC-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Sus scrofa 37240 R-XTR-6810474 https://reactome.org/PathwayBrowser/#/R-XTR-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Xenopus tropicalis 37248 R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 37248 R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 37248 R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 37248 R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 37248 R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 37248 R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 37248 R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa 37248 R-XTR-211962 https://reactome.org/PathwayBrowser/#/R-XTR-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Xenopus tropicalis 37396 R-BTA-8855711 https://reactome.org/PathwayBrowser/#/R-BTA-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Bos taurus 37396 R-CEL-8855711 https://reactome.org/PathwayBrowser/#/R-CEL-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Caenorhabditis elegans 37396 R-CFA-8855711 https://reactome.org/PathwayBrowser/#/R-CFA-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Canis familiaris 37396 R-DME-8855711 https://reactome.org/PathwayBrowser/#/R-DME-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Drosophila melanogaster 37396 R-DRE-8855711 https://reactome.org/PathwayBrowser/#/R-DRE-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Danio rerio 37396 R-GGA-8855711 https://reactome.org/PathwayBrowser/#/R-GGA-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Gallus gallus 37396 R-HSA-8855711 https://reactome.org/PathwayBrowser/#/R-HSA-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins TAS Homo sapiens 37396 R-MMU-8855711 https://reactome.org/PathwayBrowser/#/R-MMU-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Mus musculus 37396 R-RNO-8855711 https://reactome.org/PathwayBrowser/#/R-RNO-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Rattus norvegicus 37396 R-SSC-8855711 https://reactome.org/PathwayBrowser/#/R-SSC-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Sus scrofa 37396 R-XTR-8855711 https://reactome.org/PathwayBrowser/#/R-XTR-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Xenopus tropicalis 37397 R-BTA-1604763 https://reactome.org/PathwayBrowser/#/R-BTA-1604763 Autocatalytic activation of MMP7 IEA Bos taurus 37397 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 37397 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 37397 R-BTA-444773 https://reactome.org/PathwayBrowser/#/R-BTA-444773 EGF-TM7 receptors bind chondroitin sulphate IEA Bos taurus 37397 R-CEL-1604763 https://reactome.org/PathwayBrowser/#/R-CEL-1604763 Autocatalytic activation of MMP7 IEA Caenorhabditis elegans 37397 R-CFA-1604763 https://reactome.org/PathwayBrowser/#/R-CFA-1604763 Autocatalytic activation of MMP7 IEA Canis familiaris 37397 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 37397 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 37397 R-CFA-444773 https://reactome.org/PathwayBrowser/#/R-CFA-444773 EGF-TM7 receptors bind chondroitin sulphate IEA Canis familiaris 37397 R-DME-1604763 https://reactome.org/PathwayBrowser/#/R-DME-1604763 Autocatalytic activation of MMP7 IEA Drosophila melanogaster 37397 R-DME-444773 https://reactome.org/PathwayBrowser/#/R-DME-444773 EGF-TM7 receptors bind chondroitin sulphate IEA Drosophila melanogaster 37397 R-DRE-1604763 https://reactome.org/PathwayBrowser/#/R-DRE-1604763 Autocatalytic activation of MMP7 IEA Danio rerio 37397 R-GGA-1604763 https://reactome.org/PathwayBrowser/#/R-GGA-1604763 Autocatalytic activation of MMP7 IEA Gallus gallus 37397 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 37397 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 37397 R-HSA-1604763 https://reactome.org/PathwayBrowser/#/R-HSA-1604763 Autocatalytic activation of MMP7 TAS Homo sapiens 37397 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 37397 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 37397 R-HSA-444773 https://reactome.org/PathwayBrowser/#/R-HSA-444773 EGF-TM7 receptors bind chondroitin sulphate TAS Homo sapiens 37397 R-MMU-1604763 https://reactome.org/PathwayBrowser/#/R-MMU-1604763 Autocatalytic activation of MMP7 IEA Mus musculus 37397 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 37397 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 37397 R-MMU-444773 https://reactome.org/PathwayBrowser/#/R-MMU-444773 EGF-TM7 receptors bind chondroitin sulphate IEA Mus musculus 37397 R-RNO-1604763 https://reactome.org/PathwayBrowser/#/R-RNO-1604763 Autocatalytic activation of MMP7 IEA Rattus norvegicus 37397 R-RNO-444773 https://reactome.org/PathwayBrowser/#/R-RNO-444773 EGF-TM7 receptors bind chondroitin sulphate IEA Rattus norvegicus 37397 R-SSC-1604763 https://reactome.org/PathwayBrowser/#/R-SSC-1604763 Autocatalytic activation of MMP7 IEA Sus scrofa 37397 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 37397 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 37397 R-SSC-444773 https://reactome.org/PathwayBrowser/#/R-SSC-444773 EGF-TM7 receptors bind chondroitin sulphate IEA Sus scrofa 37397 R-XTR-1604763 https://reactome.org/PathwayBrowser/#/R-XTR-1604763 Autocatalytic activation of MMP7 IEA Xenopus tropicalis 37397 R-XTR-444773 https://reactome.org/PathwayBrowser/#/R-XTR-444773 EGF-TM7 receptors bind chondroitin sulphate IEA Xenopus tropicalis 37531 R-BTA-4419978 https://reactome.org/PathwayBrowser/#/R-BTA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Bos taurus 37531 R-CEL-4419978 https://reactome.org/PathwayBrowser/#/R-CEL-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Caenorhabditis elegans 37531 R-CFA-4419978 https://reactome.org/PathwayBrowser/#/R-CFA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Canis familiaris 37531 R-DDI-4419978 https://reactome.org/PathwayBrowser/#/R-DDI-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Dictyostelium discoideum 37531 R-DME-4419978 https://reactome.org/PathwayBrowser/#/R-DME-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Drosophila melanogaster 37531 R-DRE-4419978 https://reactome.org/PathwayBrowser/#/R-DRE-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Danio rerio 37531 R-GGA-4419978 https://reactome.org/PathwayBrowser/#/R-GGA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Gallus gallus 37531 R-HSA-4419978 https://reactome.org/PathwayBrowser/#/R-HSA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP TAS Homo sapiens 37531 R-HSA-4419986 https://reactome.org/PathwayBrowser/#/R-HSA-4419986 Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL TAS Homo sapiens 37531 R-MMU-4419978 https://reactome.org/PathwayBrowser/#/R-MMU-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Mus musculus 37531 R-RNO-4419978 https://reactome.org/PathwayBrowser/#/R-RNO-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Rattus norvegicus 37531 R-SCE-4419978 https://reactome.org/PathwayBrowser/#/R-SCE-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Saccharomyces cerevisiae 37531 R-SPO-4419978 https://reactome.org/PathwayBrowser/#/R-SPO-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Schizosaccharomyces pombe 37531 R-SSC-4419978 https://reactome.org/PathwayBrowser/#/R-SSC-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Sus scrofa 37563 R-BTA-1483081 https://reactome.org/PathwayBrowser/#/R-BTA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Bos taurus 37563 R-BTA-1483121 https://reactome.org/PathwayBrowser/#/R-BTA-1483121 PA is converted to CDP-DAG by CDS1 IEA Bos taurus 37563 R-BTA-1483165 https://reactome.org/PathwayBrowser/#/R-BTA-1483165 PA is converted to CDP-DAG by CDS2 IEA Bos taurus 37563 R-BTA-1483190 https://reactome.org/PathwayBrowser/#/R-BTA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Bos taurus 37563 R-BTA-4084982 https://reactome.org/PathwayBrowser/#/R-BTA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Bos taurus 37563 R-BTA-446195 https://reactome.org/PathwayBrowser/#/R-BTA-446195 DOLK phosphorylates DCHOL to DOLP IEA Bos taurus 37563 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 37563 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 37563 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 37563 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 37563 R-BTA-504054 https://reactome.org/PathwayBrowser/#/R-BTA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Bos taurus 37563 R-BTA-6814549 https://reactome.org/PathwayBrowser/#/R-BTA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Bos taurus 37563 R-BTA-6814559 https://reactome.org/PathwayBrowser/#/R-BTA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Bos taurus 37563 R-BTA-73647 https://reactome.org/PathwayBrowser/#/R-BTA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Bos taurus 37563 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 37563 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 37563 R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 37563 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 37563 R-CEL-1483081 https://reactome.org/PathwayBrowser/#/R-CEL-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Caenorhabditis elegans 37563 R-CEL-1483121 https://reactome.org/PathwayBrowser/#/R-CEL-1483121 PA is converted to CDP-DAG by CDS1 IEA Caenorhabditis elegans 37563 R-CEL-1483165 https://reactome.org/PathwayBrowser/#/R-CEL-1483165 PA is converted to CDP-DAG by CDS2 IEA Caenorhabditis elegans 37563 R-CEL-1483190 https://reactome.org/PathwayBrowser/#/R-CEL-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Caenorhabditis elegans 37563 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 37563 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 37563 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 37563 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 37563 R-CEL-504054 https://reactome.org/PathwayBrowser/#/R-CEL-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Caenorhabditis elegans 37563 R-CEL-6814559 https://reactome.org/PathwayBrowser/#/R-CEL-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Caenorhabditis elegans 37563 R-CEL-73647 https://reactome.org/PathwayBrowser/#/R-CEL-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Caenorhabditis elegans 37563 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 37563 R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 37563 R-CFA-1483081 https://reactome.org/PathwayBrowser/#/R-CFA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Canis familiaris 37563 R-CFA-1483121 https://reactome.org/PathwayBrowser/#/R-CFA-1483121 PA is converted to CDP-DAG by CDS1 IEA Canis familiaris 37563 R-CFA-1483165 https://reactome.org/PathwayBrowser/#/R-CFA-1483165 PA is converted to CDP-DAG by CDS2 IEA Canis familiaris 37563 R-CFA-1483190 https://reactome.org/PathwayBrowser/#/R-CFA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Canis familiaris 37563 R-CFA-4084982 https://reactome.org/PathwayBrowser/#/R-CFA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Canis familiaris 37563 R-CFA-446195 https://reactome.org/PathwayBrowser/#/R-CFA-446195 DOLK phosphorylates DCHOL to DOLP IEA Canis familiaris 37563 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 37563 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 37563 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 37563 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 37563 R-CFA-504054 https://reactome.org/PathwayBrowser/#/R-CFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Canis familiaris 37563 R-CFA-6814549 https://reactome.org/PathwayBrowser/#/R-CFA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Canis familiaris 37563 R-CFA-6814559 https://reactome.org/PathwayBrowser/#/R-CFA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Canis familiaris 37563 R-CFA-73647 https://reactome.org/PathwayBrowser/#/R-CFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Canis familiaris 37563 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 37563 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 37563 R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 37563 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 37563 R-DDI-1483081 https://reactome.org/PathwayBrowser/#/R-DDI-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Dictyostelium discoideum 37563 R-DDI-1483121 https://reactome.org/PathwayBrowser/#/R-DDI-1483121 PA is converted to CDP-DAG by CDS1 IEA Dictyostelium discoideum 37563 R-DDI-1483165 https://reactome.org/PathwayBrowser/#/R-DDI-1483165 PA is converted to CDP-DAG by CDS2 IEA Dictyostelium discoideum 37563 R-DDI-1483190 https://reactome.org/PathwayBrowser/#/R-DDI-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Dictyostelium discoideum 37563 R-DDI-446195 https://reactome.org/PathwayBrowser/#/R-DDI-446195 DOLK phosphorylates DCHOL to DOLP IEA Dictyostelium discoideum 37563 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 37563 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 37563 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 37563 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 37563 R-DDI-504054 https://reactome.org/PathwayBrowser/#/R-DDI-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Dictyostelium discoideum 37563 R-DDI-6814559 https://reactome.org/PathwayBrowser/#/R-DDI-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Dictyostelium discoideum 37563 R-DDI-73647 https://reactome.org/PathwayBrowser/#/R-DDI-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Dictyostelium discoideum 37563 R-DME-1483081 https://reactome.org/PathwayBrowser/#/R-DME-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Drosophila melanogaster 37563 R-DME-1483121 https://reactome.org/PathwayBrowser/#/R-DME-1483121 PA is converted to CDP-DAG by CDS1 IEA Drosophila melanogaster 37563 R-DME-1483165 https://reactome.org/PathwayBrowser/#/R-DME-1483165 PA is converted to CDP-DAG by CDS2 IEA Drosophila melanogaster 37563 R-DME-1483190 https://reactome.org/PathwayBrowser/#/R-DME-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Drosophila melanogaster 37563 R-DME-446195 https://reactome.org/PathwayBrowser/#/R-DME-446195 DOLK phosphorylates DCHOL to DOLP IEA Drosophila melanogaster 37563 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 37563 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 37563 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 37563 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 37563 R-DME-504054 https://reactome.org/PathwayBrowser/#/R-DME-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Drosophila melanogaster 37563 R-DME-6814549 https://reactome.org/PathwayBrowser/#/R-DME-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Drosophila melanogaster 37563 R-DME-6814559 https://reactome.org/PathwayBrowser/#/R-DME-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Drosophila melanogaster 37563 R-DME-73647 https://reactome.org/PathwayBrowser/#/R-DME-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Drosophila melanogaster 37563 R-DRE-1483081 https://reactome.org/PathwayBrowser/#/R-DRE-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Danio rerio 37563 R-DRE-1483165 https://reactome.org/PathwayBrowser/#/R-DRE-1483165 PA is converted to CDP-DAG by CDS2 IEA Danio rerio 37563 R-DRE-1483190 https://reactome.org/PathwayBrowser/#/R-DRE-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Danio rerio 37563 R-DRE-4084982 https://reactome.org/PathwayBrowser/#/R-DRE-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Danio rerio 37563 R-DRE-446195 https://reactome.org/PathwayBrowser/#/R-DRE-446195 DOLK phosphorylates DCHOL to DOLP IEA Danio rerio 37563 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 37563 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 37563 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 37563 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 37563 R-DRE-504054 https://reactome.org/PathwayBrowser/#/R-DRE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Danio rerio 37563 R-DRE-6814559 https://reactome.org/PathwayBrowser/#/R-DRE-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Danio rerio 37563 R-DRE-73647 https://reactome.org/PathwayBrowser/#/R-DRE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Danio rerio 37563 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 37563 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 37563 R-GGA-1483081 https://reactome.org/PathwayBrowser/#/R-GGA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Gallus gallus 37563 R-GGA-1483121 https://reactome.org/PathwayBrowser/#/R-GGA-1483121 PA is converted to CDP-DAG by CDS1 IEA Gallus gallus 37563 R-GGA-1483165 https://reactome.org/PathwayBrowser/#/R-GGA-1483165 PA is converted to CDP-DAG by CDS2 IEA Gallus gallus 37563 R-GGA-1483190 https://reactome.org/PathwayBrowser/#/R-GGA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Gallus gallus 37563 R-GGA-4084982 https://reactome.org/PathwayBrowser/#/R-GGA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Gallus gallus 37563 R-GGA-446195 https://reactome.org/PathwayBrowser/#/R-GGA-446195 DOLK phosphorylates DCHOL to DOLP IEA Gallus gallus 37563 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 37563 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 37563 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 37563 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 37563 R-GGA-504054 https://reactome.org/PathwayBrowser/#/R-GGA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Gallus gallus 37563 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus 37563 R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus 37563 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 37563 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 37563 R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 37563 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 37563 R-HSA-1483081 https://reactome.org/PathwayBrowser/#/R-HSA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer TAS Homo sapiens 37563 R-HSA-1483121 https://reactome.org/PathwayBrowser/#/R-HSA-1483121 PA is converted to CDP-DAG by CDS1 TAS Homo sapiens 37563 R-HSA-1483165 https://reactome.org/PathwayBrowser/#/R-HSA-1483165 PA is converted to CDP-DAG by CDS2 TAS Homo sapiens 37563 R-HSA-1483190 https://reactome.org/PathwayBrowser/#/R-HSA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 TAS Homo sapiens 37563 R-HSA-4084982 https://reactome.org/PathwayBrowser/#/R-HSA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac TAS Homo sapiens 37563 R-HSA-446195 https://reactome.org/PathwayBrowser/#/R-HSA-446195 DOLK phosphorylates DCHOL to DOLP TAS Homo sapiens 37563 R-HSA-4755600 https://reactome.org/PathwayBrowser/#/R-HSA-4755600 Defective DOLK does not phosphorylate DCHOL TAS Homo sapiens 37563 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 37563 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 37563 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 37563 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 37563 R-HSA-504054 https://reactome.org/PathwayBrowser/#/R-HSA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] TAS Homo sapiens 37563 R-HSA-5696807 https://reactome.org/PathwayBrowser/#/R-HSA-5696807 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 37563 R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 37563 R-HSA-6814549 https://reactome.org/PathwayBrowser/#/R-HSA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding TAS Homo sapiens 37563 R-HSA-6814559 https://reactome.org/PathwayBrowser/#/R-HSA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine TAS Homo sapiens 37563 R-HSA-73647 https://reactome.org/PathwayBrowser/#/R-HSA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] TAS Homo sapiens 37563 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 37563 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 37563 R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 37563 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 37563 R-MMU-1483081 https://reactome.org/PathwayBrowser/#/R-MMU-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Mus musculus 37563 R-MMU-1483121 https://reactome.org/PathwayBrowser/#/R-MMU-1483121 PA is converted to CDP-DAG by CDS1 IEA Mus musculus 37563 R-MMU-1483165 https://reactome.org/PathwayBrowser/#/R-MMU-1483165 PA is converted to CDP-DAG by CDS2 IEA Mus musculus 37563 R-MMU-1483190 https://reactome.org/PathwayBrowser/#/R-MMU-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Mus musculus 37563 R-MMU-4084982 https://reactome.org/PathwayBrowser/#/R-MMU-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Mus musculus 37563 R-MMU-446195 https://reactome.org/PathwayBrowser/#/R-MMU-446195 DOLK phosphorylates DCHOL to DOLP IEA Mus musculus 37563 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 37563 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 37563 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 37563 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 37563 R-MMU-504054 https://reactome.org/PathwayBrowser/#/R-MMU-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Mus musculus 37563 R-MMU-6814549 https://reactome.org/PathwayBrowser/#/R-MMU-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Mus musculus 37563 R-MMU-6814559 https://reactome.org/PathwayBrowser/#/R-MMU-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Mus musculus 37563 R-MMU-73647 https://reactome.org/PathwayBrowser/#/R-MMU-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Mus musculus 37563 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 37563 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 37563 R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 37563 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 37563 R-PFA-1483081 https://reactome.org/PathwayBrowser/#/R-PFA-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Plasmodium falciparum 37563 R-PFA-1483121 https://reactome.org/PathwayBrowser/#/R-PFA-1483121 PA is converted to CDP-DAG by CDS1 IEA Plasmodium falciparum 37563 R-PFA-1483165 https://reactome.org/PathwayBrowser/#/R-PFA-1483165 PA is converted to CDP-DAG by CDS2 IEA Plasmodium falciparum 37563 R-PFA-1483190 https://reactome.org/PathwayBrowser/#/R-PFA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Plasmodium falciparum 37563 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 37563 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 37563 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 37563 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 37563 R-PFA-504054 https://reactome.org/PathwayBrowser/#/R-PFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Plasmodium falciparum 37563 R-PFA-73647 https://reactome.org/PathwayBrowser/#/R-PFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Plasmodium falciparum 37563 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 37563 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 37563 R-RNO-1483081 https://reactome.org/PathwayBrowser/#/R-RNO-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Rattus norvegicus 37563 R-RNO-1483121 https://reactome.org/PathwayBrowser/#/R-RNO-1483121 PA is converted to CDP-DAG by CDS1 IEA Rattus norvegicus 37563 R-RNO-1483165 https://reactome.org/PathwayBrowser/#/R-RNO-1483165 PA is converted to CDP-DAG by CDS2 IEA Rattus norvegicus 37563 R-RNO-1483190 https://reactome.org/PathwayBrowser/#/R-RNO-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Rattus norvegicus 37563 R-RNO-4084982 https://reactome.org/PathwayBrowser/#/R-RNO-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Rattus norvegicus 37563 R-RNO-446195 https://reactome.org/PathwayBrowser/#/R-RNO-446195 DOLK phosphorylates DCHOL to DOLP IEA Rattus norvegicus 37563 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 37563 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 37563 R-RNO-504054 https://reactome.org/PathwayBrowser/#/R-RNO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Rattus norvegicus 37563 R-RNO-6814549 https://reactome.org/PathwayBrowser/#/R-RNO-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Rattus norvegicus 37563 R-RNO-6814559 https://reactome.org/PathwayBrowser/#/R-RNO-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Rattus norvegicus 37563 R-RNO-73647 https://reactome.org/PathwayBrowser/#/R-RNO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Rattus norvegicus 37563 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 37563 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 37563 R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 37563 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 37563 R-SCE-1483081 https://reactome.org/PathwayBrowser/#/R-SCE-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Saccharomyces cerevisiae 37563 R-SCE-1483121 https://reactome.org/PathwayBrowser/#/R-SCE-1483121 PA is converted to CDP-DAG by CDS1 IEA Saccharomyces cerevisiae 37563 R-SCE-1483165 https://reactome.org/PathwayBrowser/#/R-SCE-1483165 PA is converted to CDP-DAG by CDS2 IEA Saccharomyces cerevisiae 37563 R-SCE-1483190 https://reactome.org/PathwayBrowser/#/R-SCE-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Saccharomyces cerevisiae 37563 R-SCE-446195 https://reactome.org/PathwayBrowser/#/R-SCE-446195 DOLK phosphorylates DCHOL to DOLP IEA Saccharomyces cerevisiae 37563 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 37563 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 37563 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 37563 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 37563 R-SCE-504054 https://reactome.org/PathwayBrowser/#/R-SCE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Saccharomyces cerevisiae 37563 R-SCE-73647 https://reactome.org/PathwayBrowser/#/R-SCE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Saccharomyces cerevisiae 37563 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 37563 R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 37563 R-SPO-1483081 https://reactome.org/PathwayBrowser/#/R-SPO-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Schizosaccharomyces pombe 37563 R-SPO-1483121 https://reactome.org/PathwayBrowser/#/R-SPO-1483121 PA is converted to CDP-DAG by CDS1 IEA Schizosaccharomyces pombe 37563 R-SPO-1483165 https://reactome.org/PathwayBrowser/#/R-SPO-1483165 PA is converted to CDP-DAG by CDS2 IEA Schizosaccharomyces pombe 37563 R-SPO-1483190 https://reactome.org/PathwayBrowser/#/R-SPO-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Schizosaccharomyces pombe 37563 R-SPO-446195 https://reactome.org/PathwayBrowser/#/R-SPO-446195 DOLK phosphorylates DCHOL to DOLP IEA Schizosaccharomyces pombe 37563 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 37563 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 37563 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 37563 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 37563 R-SPO-504054 https://reactome.org/PathwayBrowser/#/R-SPO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Schizosaccharomyces pombe 37563 R-SPO-73647 https://reactome.org/PathwayBrowser/#/R-SPO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Schizosaccharomyces pombe 37563 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 37563 R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 37563 R-SSC-1483081 https://reactome.org/PathwayBrowser/#/R-SSC-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Sus scrofa 37563 R-SSC-1483121 https://reactome.org/PathwayBrowser/#/R-SSC-1483121 PA is converted to CDP-DAG by CDS1 IEA Sus scrofa 37563 R-SSC-1483165 https://reactome.org/PathwayBrowser/#/R-SSC-1483165 PA is converted to CDP-DAG by CDS2 IEA Sus scrofa 37563 R-SSC-1483190 https://reactome.org/PathwayBrowser/#/R-SSC-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Sus scrofa 37563 R-SSC-4084982 https://reactome.org/PathwayBrowser/#/R-SSC-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Sus scrofa 37563 R-SSC-446195 https://reactome.org/PathwayBrowser/#/R-SSC-446195 DOLK phosphorylates DCHOL to DOLP IEA Sus scrofa 37563 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 37563 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 37563 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 37563 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 37563 R-SSC-504054 https://reactome.org/PathwayBrowser/#/R-SSC-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Sus scrofa 37563 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa 37563 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa 37563 R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa 37563 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 37563 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 37563 R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 37563 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 37563 R-XTR-1483081 https://reactome.org/PathwayBrowser/#/R-XTR-1483081 PCho and CTP are condensed to CDP-Cho by PCYT1 dimer IEA Xenopus tropicalis 37563 R-XTR-1483121 https://reactome.org/PathwayBrowser/#/R-XTR-1483121 PA is converted to CDP-DAG by CDS1 IEA Xenopus tropicalis 37563 R-XTR-1483165 https://reactome.org/PathwayBrowser/#/R-XTR-1483165 PA is converted to CDP-DAG by CDS2 IEA Xenopus tropicalis 37563 R-XTR-1483190 https://reactome.org/PathwayBrowser/#/R-XTR-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Xenopus tropicalis 37563 R-XTR-4084982 https://reactome.org/PathwayBrowser/#/R-XTR-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Xenopus tropicalis 37563 R-XTR-446195 https://reactome.org/PathwayBrowser/#/R-XTR-446195 DOLK phosphorylates DCHOL to DOLP IEA Xenopus tropicalis 37563 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 37563 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 37563 R-XTR-6814559 https://reactome.org/PathwayBrowser/#/R-XTR-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Xenopus tropicalis 37563 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 37563 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 37563 R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 37563 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 37565 R-BTA-1008248 https://reactome.org/PathwayBrowser/#/R-BTA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Bos taurus 37565 R-BTA-111524 https://reactome.org/PathwayBrowser/#/R-BTA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Bos taurus 37565 R-BTA-111879 https://reactome.org/PathwayBrowser/#/R-BTA-111879 PIP2 hydrolysis IEA Bos taurus 37565 R-BTA-112037 https://reactome.org/PathwayBrowser/#/R-BTA-112037 Inactivation of PLC beta IEA Bos taurus 37565 R-BTA-112271 https://reactome.org/PathwayBrowser/#/R-BTA-112271 The receptor:G-protein complex dissociates IEA Bos taurus 37565 R-BTA-114542 https://reactome.org/PathwayBrowser/#/R-BTA-114542 RAC1,RAC2,RHOG activate PI3K IEA Bos taurus 37565 R-BTA-114544 https://reactome.org/PathwayBrowser/#/R-BTA-114544 p115-RhoGEF activation of RHOA IEA Bos taurus 37565 R-BTA-114548 https://reactome.org/PathwayBrowser/#/R-BTA-114548 G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) IEA Bos taurus 37565 R-BTA-114552 https://reactome.org/PathwayBrowser/#/R-BTA-114552 Thrombin-activated PARs activate G12/13 IEA Bos taurus 37565 R-BTA-114558 https://reactome.org/PathwayBrowser/#/R-BTA-114558 Thrombin-activated PARs activate Gq IEA Bos taurus 37565 R-BTA-114688 https://reactome.org/PathwayBrowser/#/R-BTA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Bos taurus 37565 R-BTA-1168636 https://reactome.org/PathwayBrowser/#/R-BTA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Bos taurus 37565 R-BTA-1250383 https://reactome.org/PathwayBrowser/#/R-BTA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Bos taurus 37565 R-BTA-1306972 https://reactome.org/PathwayBrowser/#/R-BTA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Bos taurus 37565 R-BTA-1433415 https://reactome.org/PathwayBrowser/#/R-BTA-1433415 Activation of RAC1 IEA Bos taurus 37565 R-BTA-1433471 https://reactome.org/PathwayBrowser/#/R-BTA-1433471 Activation of RAS by p-KIT bound SOS1 IEA Bos taurus 37565 R-BTA-1474146 https://reactome.org/PathwayBrowser/#/R-BTA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Bos taurus 37565 R-BTA-156808 https://reactome.org/PathwayBrowser/#/R-BTA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Bos taurus 37565 R-BTA-156823 https://reactome.org/PathwayBrowser/#/R-BTA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Bos taurus 37565 R-BTA-156913 https://reactome.org/PathwayBrowser/#/R-BTA-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Bos taurus 37565 R-BTA-156930 https://reactome.org/PathwayBrowser/#/R-BTA-156930 GTP-binding activates eEF2 IEA Bos taurus 37565 R-BTA-157849 https://reactome.org/PathwayBrowser/#/R-BTA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Bos taurus 37565 R-BTA-1638803 https://reactome.org/PathwayBrowser/#/R-BTA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Bos taurus 37565 R-BTA-1638821 https://reactome.org/PathwayBrowser/#/R-BTA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Bos taurus 37565 R-BTA-165195 https://reactome.org/PathwayBrowser/#/R-BTA-165195 GTP loading by Rheb IEA Bos taurus 37565 R-BTA-165680 https://reactome.org/PathwayBrowser/#/R-BTA-165680 Formation of active mTORC1 complex IEA Bos taurus 37565 R-BTA-165692 https://reactome.org/PathwayBrowser/#/R-BTA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Bos taurus 37565 R-BTA-165718 https://reactome.org/PathwayBrowser/#/R-BTA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Bos taurus 37565 R-BTA-167415 https://reactome.org/PathwayBrowser/#/R-BTA-167415 G-protein alpha subunit is inactivated IEA Bos taurus 37565 R-BTA-167429 https://reactome.org/PathwayBrowser/#/R-BTA-167429 The receptor:G-protein complex binds GTP IEA Bos taurus 37565 R-BTA-169904 https://reactome.org/PathwayBrowser/#/R-BTA-169904 C3G stimulates nucleotide exchange on Rap1 IEA Bos taurus 37565 R-BTA-170026 https://reactome.org/PathwayBrowser/#/R-BTA-170026 Protons are translocated from the intermembrane space to the matrix IEA Bos taurus 37565 R-BTA-170666 https://reactome.org/PathwayBrowser/#/R-BTA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Bos taurus 37565 R-BTA-170671 https://reactome.org/PathwayBrowser/#/R-BTA-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Bos taurus 37565 R-BTA-170672 https://reactome.org/PathwayBrowser/#/R-BTA-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Bos taurus 37565 R-BTA-170676 https://reactome.org/PathwayBrowser/#/R-BTA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Bos taurus 37565 R-BTA-170685 https://reactome.org/PathwayBrowser/#/R-BTA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Bos taurus 37565 R-BTA-170686 https://reactome.org/PathwayBrowser/#/R-BTA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Bos taurus 37565 R-BTA-170986 https://reactome.org/PathwayBrowser/#/R-BTA-170986 Ral-GDS binds to Ras-GTP IEA Bos taurus 37565 R-BTA-177938 https://reactome.org/PathwayBrowser/#/R-BTA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Bos taurus 37565 R-BTA-177945 https://reactome.org/PathwayBrowser/#/R-BTA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Bos taurus 37565 R-BTA-183002 https://reactome.org/PathwayBrowser/#/R-BTA-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Bos taurus 37565 R-BTA-183084 https://reactome.org/PathwayBrowser/#/R-BTA-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Bos taurus 37565 R-BTA-183094 https://reactome.org/PathwayBrowser/#/R-BTA-183094 CDC42:GTP binds CBL:Beta-Pix IEA Bos taurus 37565 R-BTA-186834 https://reactome.org/PathwayBrowser/#/R-BTA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Bos taurus 37565 R-BTA-190520 https://reactome.org/PathwayBrowser/#/R-BTA-190520 Association of Golgi transport vesicles with microtubules IEA Bos taurus 37565 R-BTA-194518 https://reactome.org/PathwayBrowser/#/R-BTA-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Bos taurus 37565 R-BTA-2029451 https://reactome.org/PathwayBrowser/#/R-BTA-2029451 Activation of RAC1 by VAV IEA Bos taurus 37565 R-BTA-2029454 https://reactome.org/PathwayBrowser/#/R-BTA-2029454 Autophosphorylation of PAK1 IEA Bos taurus 37565 R-BTA-2029456 https://reactome.org/PathwayBrowser/#/R-BTA-2029456 RAC1 and CDC42 activate PAK1 IEA Bos taurus 37565 R-BTA-2029465 https://reactome.org/PathwayBrowser/#/R-BTA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Bos taurus 37565 R-BTA-2029466 https://reactome.org/PathwayBrowser/#/R-BTA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Bos taurus 37565 R-BTA-2029467 https://reactome.org/PathwayBrowser/#/R-BTA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Bos taurus 37565 R-BTA-2029469 https://reactome.org/PathwayBrowser/#/R-BTA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Bos taurus 37565 R-BTA-203973 https://reactome.org/PathwayBrowser/#/R-BTA-203973 Vesicle budding IEA Bos taurus 37565 R-BTA-203977 https://reactome.org/PathwayBrowser/#/R-BTA-203977 SAR1 Activation And Membrane Binding IEA Bos taurus 37565 R-BTA-203979 https://reactome.org/PathwayBrowser/#/R-BTA-203979 Coat Assembly IEA Bos taurus 37565 R-BTA-204008 https://reactome.org/PathwayBrowser/#/R-BTA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Bos taurus 37565 R-BTA-205039 https://reactome.org/PathwayBrowser/#/R-BTA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Bos taurus 37565 R-BTA-205136 https://reactome.org/PathwayBrowser/#/R-BTA-205136 GTP-bound RAC contributes to JNK activation IEA Bos taurus 37565 R-BTA-2065539 https://reactome.org/PathwayBrowser/#/R-BTA-2065539 SREBP1A,1C,2:Importin beta-1 dissociates IEA Bos taurus 37565 R-BTA-210977 https://reactome.org/PathwayBrowser/#/R-BTA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Bos taurus 37565 R-BTA-2130194 https://reactome.org/PathwayBrowser/#/R-BTA-2130194 ABL phosphorylates WAVEs IEA Bos taurus 37565 R-BTA-2130619 https://reactome.org/PathwayBrowser/#/R-BTA-2130619 TGN-lysosomal vesicle coat assembly IEA Bos taurus 37565 R-BTA-2130641 https://reactome.org/PathwayBrowser/#/R-BTA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Bos taurus 37565 R-BTA-2130725 https://reactome.org/PathwayBrowser/#/R-BTA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Bos taurus 37565 R-BTA-2130731 https://reactome.org/PathwayBrowser/#/R-BTA-2130731 Formation of COPII vesicle IEA Bos taurus 37565 R-BTA-2179407 https://reactome.org/PathwayBrowser/#/R-BTA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Bos taurus 37565 R-BTA-2197690 https://reactome.org/PathwayBrowser/#/R-BTA-2197690 Detachment of WASP/WAVE IEA Bos taurus 37565 R-BTA-2197698 https://reactome.org/PathwayBrowser/#/R-BTA-2197698 Src phosphorylate WASP,N-WASP IEA Bos taurus 37565 R-BTA-2213243 https://reactome.org/PathwayBrowser/#/R-BTA-2213243 Fusion of COPII vesicle with Golgi complex IEA Bos taurus 37565 R-BTA-2213248 https://reactome.org/PathwayBrowser/#/R-BTA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Bos taurus 37565 R-BTA-2214351 https://reactome.org/PathwayBrowser/#/R-BTA-2214351 PLK1 phosphorylates GORASP1 IEA Bos taurus 37565 R-BTA-2316434 https://reactome.org/PathwayBrowser/#/R-BTA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 37565 R-BTA-2422927 https://reactome.org/PathwayBrowser/#/R-BTA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Bos taurus 37565 R-BTA-2424476 https://reactome.org/PathwayBrowser/#/R-BTA-2424476 Activation of RAC1 by VAV2/3 IEA Bos taurus 37565 R-BTA-2424477 https://reactome.org/PathwayBrowser/#/R-BTA-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Bos taurus 37565 R-BTA-2467809 https://reactome.org/PathwayBrowser/#/R-BTA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Bos taurus 37565 R-BTA-2467811 https://reactome.org/PathwayBrowser/#/R-BTA-2467811 Separation of sister chromatids IEA Bos taurus 37565 R-BTA-2468287 https://reactome.org/PathwayBrowser/#/R-BTA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Bos taurus 37565 R-BTA-2484822 https://reactome.org/PathwayBrowser/#/R-BTA-2484822 Kinetochore assembly IEA Bos taurus 37565 R-BTA-2485182 https://reactome.org/PathwayBrowser/#/R-BTA-2485182 Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 IEA Bos taurus 37565 R-BTA-2530504 https://reactome.org/PathwayBrowser/#/R-BTA-2530504 MII catalyses GDP/GTP exchange on Gt TAS Bos taurus 37565 R-BTA-2562526 https://reactome.org/PathwayBrowser/#/R-BTA-2562526 PLK1 phosphorylates OPTN IEA Bos taurus 37565 R-BTA-2584246 https://reactome.org/PathwayBrowser/#/R-BTA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Bos taurus 37565 R-BTA-2730840 https://reactome.org/PathwayBrowser/#/R-BTA-2730840 Activation of RAC1 by VAV IEA Bos taurus 37565 R-BTA-2730856 https://reactome.org/PathwayBrowser/#/R-BTA-2730856 Autophosphorylation of PAK IEA Bos taurus 37565 R-BTA-2730889 https://reactome.org/PathwayBrowser/#/R-BTA-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Bos taurus 37565 R-BTA-350769 https://reactome.org/PathwayBrowser/#/R-BTA-350769 trans-Golgi Network Coat Activation IEA Bos taurus 37565 R-BTA-354060 https://reactome.org/PathwayBrowser/#/R-BTA-354060 Translocation of RIAM to plasma membrane IEA Bos taurus 37565 R-BTA-354066 https://reactome.org/PathwayBrowser/#/R-BTA-354066 Translocation of PTK2 to Focal complexes IEA Bos taurus 37565 R-BTA-354073 https://reactome.org/PathwayBrowser/#/R-BTA-354073 Autophosphorylation of PTK2 at Y397 IEA Bos taurus 37565 R-BTA-354077 https://reactome.org/PathwayBrowser/#/R-BTA-354077 Integrin alphaIIb beta3 activation IEA Bos taurus 37565 R-BTA-354087 https://reactome.org/PathwayBrowser/#/R-BTA-354087 Recruitment of GRB2 to p-PTK2 IEA Bos taurus 37565 R-BTA-354097 https://reactome.org/PathwayBrowser/#/R-BTA-354097 Activation of Talin IEA Bos taurus 37565 R-BTA-354124 https://reactome.org/PathwayBrowser/#/R-BTA-354124 Phosphorylation of pPTK2 by SRC IEA Bos taurus 37565 R-BTA-354149 https://reactome.org/PathwayBrowser/#/R-BTA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Bos taurus 37565 R-BTA-354165 https://reactome.org/PathwayBrowser/#/R-BTA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Bos taurus 37565 R-BTA-354173 https://reactome.org/PathwayBrowser/#/R-BTA-354173 Activation of Rap1 by cytosolic GEFs IEA Bos taurus 37565 R-BTA-372693 https://reactome.org/PathwayBrowser/#/R-BTA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Bos taurus 37565 R-BTA-372697 https://reactome.org/PathwayBrowser/#/R-BTA-372697 Crk binding to p130cas IEA Bos taurus 37565 R-BTA-372705 https://reactome.org/PathwayBrowser/#/R-BTA-372705 Recruitment of BCAR1 to PTK2 complex IEA Bos taurus 37565 R-BTA-372819 https://reactome.org/PathwayBrowser/#/R-BTA-372819 PCK2 phosphorylates OA to yield PEP IEA Bos taurus 37565 R-BTA-374858 https://reactome.org/PathwayBrowser/#/R-BTA-374858 Activation of PLC beta-1 TAS Bos taurus 37565 R-BTA-375302 https://reactome.org/PathwayBrowser/#/R-BTA-375302 Kinetochore capture of astral microtubules IEA Bos taurus 37565 R-BTA-377640 https://reactome.org/PathwayBrowser/#/R-BTA-377640 Autophosphorylation of SRC IEA Bos taurus 37565 R-BTA-377641 https://reactome.org/PathwayBrowser/#/R-BTA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Bos taurus 37565 R-BTA-377643 https://reactome.org/PathwayBrowser/#/R-BTA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Bos taurus 37565 R-BTA-377644 https://reactome.org/PathwayBrowser/#/R-BTA-377644 Release of CSK from SRC IEA Bos taurus 37565 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 37565 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 37565 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 37565 R-BTA-380316 https://reactome.org/PathwayBrowser/#/R-BTA-380316 Association of NuMA with microtubules IEA Bos taurus 37565 R-BTA-380979 https://reactome.org/PathwayBrowser/#/R-BTA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Bos taurus 37565 R-BTA-381727 https://reactome.org/PathwayBrowser/#/R-BTA-381727 RAP1A exchanges GDP for GTP IEA Bos taurus 37565 R-BTA-3858475 https://reactome.org/PathwayBrowser/#/R-BTA-3858475 ppDVL recruits RAC IEA Bos taurus 37565 R-BTA-3858495 https://reactome.org/PathwayBrowser/#/R-BTA-3858495 DAAM1 recruits GTP-bound RHOA IEA Bos taurus 37565 R-BTA-389348 https://reactome.org/PathwayBrowser/#/R-BTA-389348 Activation of Rac1 by pVav1 IEA Bos taurus 37565 R-BTA-389350 https://reactome.org/PathwayBrowser/#/R-BTA-389350 Activation of Cdc42 by pVav1 IEA Bos taurus 37565 R-BTA-389788 https://reactome.org/PathwayBrowser/#/R-BTA-389788 Activation of PAKs by RAC1 and CDC42 IEA Bos taurus 37565 R-BTA-391512 https://reactome.org/PathwayBrowser/#/R-BTA-391512 Beta-tubulin:GTP:Cofactor D+alpha-tubulin:GTP:Cofactor E-> Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E TAS Bos taurus 37565 R-BTA-391513 https://reactome.org/PathwayBrowser/#/R-BTA-391513 alpha-tubulin:GTP + Cofactor B -> alpha-tubulin:GTP: Cofactor B TAS Bos taurus 37565 R-BTA-391517 https://reactome.org/PathwayBrowser/#/R-BTA-391517 Beta-tubulin:GTP: Cofactor A+ Cofactor D -> Beta-tubulin:GTP:Cofactor D + Cofactor A TAS Bos taurus 37565 R-BTA-391519 https://reactome.org/PathwayBrowser/#/R-BTA-391519 alpha-tubulin:GTP + Cofactor E -> alpha-tubulin:GTP:Cofactor E TAS Bos taurus 37565 R-BTA-391520 https://reactome.org/PathwayBrowser/#/R-BTA-391520 Beta-tubulin:GTP + Cofactor D -> Beta-tubulin:GTP: Cofactor D TAS Bos taurus 37565 R-BTA-391521 https://reactome.org/PathwayBrowser/#/R-BTA-391521 Beta-tubulin:GTP + Cofactor A -> Beta-tubulin:GTP: Cofactor A TAS Bos taurus 37565 R-BTA-391522 https://reactome.org/PathwayBrowser/#/R-BTA-391522 Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E+ Cofactor C-> Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E:Cofactor C TAS Bos taurus 37565 R-BTA-391533 https://reactome.org/PathwayBrowser/#/R-BTA-391533 Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E:Cofactor C-> Beta-tubulin:GDP :alpha-tubulin:GTP heterodimer +Cofactor E+ Cofactor D+ Cofactor C+ Pi TAS Bos taurus 37565 R-BTA-392054 https://reactome.org/PathwayBrowser/#/R-BTA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Bos taurus 37565 R-BTA-392064 https://reactome.org/PathwayBrowser/#/R-BTA-392064 G alpha (z) inhibits adenylate cyclase IEA Bos taurus 37565 R-BTA-392195 https://reactome.org/PathwayBrowser/#/R-BTA-392195 Gi activation by P2Y purinoceptor 12 IEA Bos taurus 37565 R-BTA-392202 https://reactome.org/PathwayBrowser/#/R-BTA-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Bos taurus 37565 R-BTA-392513 https://reactome.org/PathwayBrowser/#/R-BTA-392513 Rap1 signal termination by Rap1GAPs IEA Bos taurus 37565 R-BTA-3928576 https://reactome.org/PathwayBrowser/#/R-BTA-3928576 RHOA:GTP binds ROCK, activating it IEA Bos taurus 37565 R-BTA-3928592 https://reactome.org/PathwayBrowser/#/R-BTA-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Bos taurus 37565 R-BTA-3928595 https://reactome.org/PathwayBrowser/#/R-BTA-3928595 N-WASP binds ARP2/3 and G-actin IEA Bos taurus 37565 R-BTA-3928601 https://reactome.org/PathwayBrowser/#/R-BTA-3928601 CDC42 and PIP2 bind WASL, activating it IEA Bos taurus 37565 R-BTA-3928619 https://reactome.org/PathwayBrowser/#/R-BTA-3928619 PAK1 binds RAC1:GTP IEA Bos taurus 37565 R-BTA-3928620 https://reactome.org/PathwayBrowser/#/R-BTA-3928620 PAK1 autophosphorylates IEA Bos taurus 37565 R-BTA-3928625 https://reactome.org/PathwayBrowser/#/R-BTA-3928625 PAKs autophosphorylate IEA Bos taurus 37565 R-BTA-3928628 https://reactome.org/PathwayBrowser/#/R-BTA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Bos taurus 37565 R-BTA-3928633 https://reactome.org/PathwayBrowser/#/R-BTA-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Bos taurus 37565 R-BTA-3928640 https://reactome.org/PathwayBrowser/#/R-BTA-3928640 PAKs phosphorylate MLC IEA Bos taurus 37565 R-BTA-3928641 https://reactome.org/PathwayBrowser/#/R-BTA-3928641 PAK binds RAC and bPIX IEA Bos taurus 37565 R-BTA-3928642 https://reactome.org/PathwayBrowser/#/R-BTA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Bos taurus 37565 R-BTA-3928647 https://reactome.org/PathwayBrowser/#/R-BTA-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Bos taurus 37565 R-BTA-3928651 https://reactome.org/PathwayBrowser/#/R-BTA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Bos taurus 37565 R-BTA-392870 https://reactome.org/PathwayBrowser/#/R-BTA-392870 Gs activation by prostacyclin receptor IEA Bos taurus 37565 R-BTA-3965444 https://reactome.org/PathwayBrowser/#/R-BTA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Bos taurus 37565 R-BTA-3965447 https://reactome.org/PathwayBrowser/#/R-BTA-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Bos taurus 37565 R-BTA-397835 https://reactome.org/PathwayBrowser/#/R-BTA-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Bos taurus 37565 R-BTA-397891 https://reactome.org/PathwayBrowser/#/R-BTA-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Bos taurus 37565 R-BTA-398184 https://reactome.org/PathwayBrowser/#/R-BTA-398184 LARG activation by G alpha 12/13 IEA Bos taurus 37565 R-BTA-398185 https://reactome.org/PathwayBrowser/#/R-BTA-398185 LARG binds plexin B1 IEA Bos taurus 37565 R-BTA-399930 https://reactome.org/PathwayBrowser/#/R-BTA-399930 Activation of PAK by Rac1 IEA Bos taurus 37565 R-BTA-399939 https://reactome.org/PathwayBrowser/#/R-BTA-399939 Autophosphorylation of PAK IEA Bos taurus 37565 R-BTA-399952 https://reactome.org/PathwayBrowser/#/R-BTA-399952 Phosphorylation of LIMK-1 by PAK IEA Bos taurus 37565 R-BTA-399998 https://reactome.org/PathwayBrowser/#/R-BTA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Bos taurus 37565 R-BTA-400037 https://reactome.org/PathwayBrowser/#/R-BTA-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Bos taurus 37565 R-BTA-400092 https://reactome.org/PathwayBrowser/#/R-BTA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Bos taurus 37565 R-BTA-400586 https://reactome.org/PathwayBrowser/#/R-BTA-400586 G alpha (q) binds to Trio family RhoGEFs IEA Bos taurus 37565 R-BTA-400677 https://reactome.org/PathwayBrowser/#/R-BTA-400677 Rnd1 interacts with Plexin-B1:Sema4D IEA Bos taurus 37565 R-BTA-400682 https://reactome.org/PathwayBrowser/#/R-BTA-400682 Active Rac1 interacts with Plexin-B1:Sema4D IEA Bos taurus 37565 R-BTA-4086392 https://reactome.org/PathwayBrowser/#/R-BTA-4086392 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 37565 R-BTA-4093331 https://reactome.org/PathwayBrowser/#/R-BTA-4093331 Ras:GTP binds p120-RasGAP IEA Bos taurus 37565 R-BTA-4093339 https://reactome.org/PathwayBrowser/#/R-BTA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Bos taurus 37565 R-BTA-416358 https://reactome.org/PathwayBrowser/#/R-BTA-416358 G alpha (q) inhibits PI3K alpha IEA Bos taurus 37565 R-BTA-416516 https://reactome.org/PathwayBrowser/#/R-BTA-416516 GRK2 sequesters activated Gq IEA Bos taurus 37565 R-BTA-416530 https://reactome.org/PathwayBrowser/#/R-BTA-416530 FFAR1:FFAR1 ligands activate Gq IEA Bos taurus 37565 R-BTA-416546 https://reactome.org/PathwayBrowser/#/R-BTA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Bos taurus 37565 R-BTA-416559 https://reactome.org/PathwayBrowser/#/R-BTA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Bos taurus 37565 R-BTA-416562 https://reactome.org/PathwayBrowser/#/R-BTA-416562 p190RhoGAP binds Plexin-B1 IEA Bos taurus 37565 R-BTA-416588 https://reactome.org/PathwayBrowser/#/R-BTA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Bos taurus 37565 R-BTA-418574 https://reactome.org/PathwayBrowser/#/R-BTA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Bos taurus 37565 R-BTA-418576 https://reactome.org/PathwayBrowser/#/R-BTA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Bos taurus 37565 R-BTA-418582 https://reactome.org/PathwayBrowser/#/R-BTA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Bos taurus 37565 R-BTA-418850 https://reactome.org/PathwayBrowser/#/R-BTA-418850 Activation of Cdc42 IEA Bos taurus 37565 R-BTA-418856 https://reactome.org/PathwayBrowser/#/R-BTA-418856 Activation of Rac1 IEA Bos taurus 37565 R-BTA-418874 https://reactome.org/PathwayBrowser/#/R-BTA-418874 Recruitment and activation of N-WASP by Cdc42 IEA Bos taurus 37565 R-BTA-419049 https://reactome.org/PathwayBrowser/#/R-BTA-419049 ROCK activation by RHO IEA Bos taurus 37565 R-BTA-419166 https://reactome.org/PathwayBrowser/#/R-BTA-419166 GEFs activate RhoA,B,C IEA Bos taurus 37565 R-BTA-420883 https://reactome.org/PathwayBrowser/#/R-BTA-420883 Opsins act as GEFs for G alpha-t IEA Bos taurus 37565 R-BTA-421831 https://reactome.org/PathwayBrowser/#/R-BTA-421831 trans-Golgi Network Coat Assembly IEA Bos taurus 37565 R-BTA-421835 https://reactome.org/PathwayBrowser/#/R-BTA-421835 trans-Golgi Network Vesicle Scission IEA Bos taurus 37565 R-BTA-428750 https://reactome.org/PathwayBrowser/#/R-BTA-428750 Gq activation by TP receptor IEA Bos taurus 37565 R-BTA-428752 https://reactome.org/PathwayBrowser/#/R-BTA-428752 Dissociation of the TP:Gq complex IEA Bos taurus 37565 R-BTA-428917 https://reactome.org/PathwayBrowser/#/R-BTA-428917 G13 activation by TP receptor IEA Bos taurus 37565 R-BTA-428918 https://reactome.org/PathwayBrowser/#/R-BTA-428918 Dissociation of the TP:G13 complex IEA Bos taurus 37565 R-BTA-428941 https://reactome.org/PathwayBrowser/#/R-BTA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Bos taurus 37565 R-BTA-429415 https://reactome.org/PathwayBrowser/#/R-BTA-429415 SYK binds to integrin alphaIIb beta3 IEA Bos taurus 37565 R-BTA-429441 https://reactome.org/PathwayBrowser/#/R-BTA-429441 SYK activation by SRC IEA Bos taurus 37565 R-BTA-432096 https://reactome.org/PathwayBrowser/#/R-BTA-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Bos taurus 37565 R-BTA-432195 https://reactome.org/PathwayBrowser/#/R-BTA-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Bos taurus 37565 R-BTA-432706 https://reactome.org/PathwayBrowser/#/R-BTA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Bos taurus 37565 R-BTA-432707 https://reactome.org/PathwayBrowser/#/R-BTA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Bos taurus 37565 R-BTA-442273 https://reactome.org/PathwayBrowser/#/R-BTA-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Bos taurus 37565 R-BTA-442291 https://reactome.org/PathwayBrowser/#/R-BTA-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Bos taurus 37565 R-BTA-442314 https://reactome.org/PathwayBrowser/#/R-BTA-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Bos taurus 37565 R-BTA-443905 https://reactome.org/PathwayBrowser/#/R-BTA-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Bos taurus 37565 R-BTA-443910 https://reactome.org/PathwayBrowser/#/R-BTA-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Bos taurus 37565 R-BTA-445064 https://reactome.org/PathwayBrowser/#/R-BTA-445064 Activation of Rac1 by VAV2 IEA Bos taurus 37565 R-BTA-445072 https://reactome.org/PathwayBrowser/#/R-BTA-445072 Interaction of PAK1 with Rac1-GTP IEA Bos taurus 37565 R-BTA-447074 https://reactome.org/PathwayBrowser/#/R-BTA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Bos taurus 37565 R-BTA-448958 https://reactome.org/PathwayBrowser/#/R-BTA-448958 Nuclear translocation of p38 MAPK IEA Bos taurus 37565 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 37565 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 37565 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 37565 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 37565 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 37565 R-BTA-5218804 https://reactome.org/PathwayBrowser/#/R-BTA-5218804 p38 MAPK activation by VEGFR IEA Bos taurus 37565 R-BTA-5218812 https://reactome.org/PathwayBrowser/#/R-BTA-5218812 FYN phosphorylates PAK2 IEA Bos taurus 37565 R-BTA-5218814 https://reactome.org/PathwayBrowser/#/R-BTA-5218814 PAK2 autophorylates IEA Bos taurus 37565 R-BTA-5218826 https://reactome.org/PathwayBrowser/#/R-BTA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Bos taurus 37565 R-BTA-5218827 https://reactome.org/PathwayBrowser/#/R-BTA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Bos taurus 37565 R-BTA-5218832 https://reactome.org/PathwayBrowser/#/R-BTA-5218832 CDC42:GTP binds PAK2 IEA Bos taurus 37565 R-BTA-5218839 https://reactome.org/PathwayBrowser/#/R-BTA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Bos taurus 37565 R-BTA-5218841 https://reactome.org/PathwayBrowser/#/R-BTA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Bos taurus 37565 R-BTA-5218845 https://reactome.org/PathwayBrowser/#/R-BTA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Bos taurus 37565 R-BTA-5218850 https://reactome.org/PathwayBrowser/#/R-BTA-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Bos taurus 37565 R-BTA-5228992 https://reactome.org/PathwayBrowser/#/R-BTA-5228992 ROCK1,ROCK2 are activated IEA Bos taurus 37565 R-BTA-5250209 https://reactome.org/PathwayBrowser/#/R-BTA-5250209 ARL2:GTP:ARL2BP binds SLC25A4 IEA Bos taurus 37565 R-BTA-5250210 https://reactome.org/PathwayBrowser/#/R-BTA-5250210 ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix IEA Bos taurus 37565 R-BTA-5250217 https://reactome.org/PathwayBrowser/#/R-BTA-5250217 ARL2:GTP binds ARL2BP IEA Bos taurus 37565 R-BTA-5357445 https://reactome.org/PathwayBrowser/#/R-BTA-5357445 PAK1-3 dimer disassociates IEA Bos taurus 37565 R-BTA-5357472 https://reactome.org/PathwayBrowser/#/R-BTA-5357472 PAK1-3 autophosphorylates IEA Bos taurus 37565 R-BTA-5357483 https://reactome.org/PathwayBrowser/#/R-BTA-5357483 RAC1 binds PAK1-3 IEA Bos taurus 37565 R-BTA-5419261 https://reactome.org/PathwayBrowser/#/R-BTA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Bos taurus 37565 R-BTA-5419264 https://reactome.org/PathwayBrowser/#/R-BTA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Bos taurus 37565 R-BTA-5419271 https://reactome.org/PathwayBrowser/#/R-BTA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Bos taurus 37565 R-BTA-5419273 https://reactome.org/PathwayBrowser/#/R-BTA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Bos taurus 37565 R-BTA-5432387 https://reactome.org/PathwayBrowser/#/R-BTA-5432387 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA TAS Bos taurus 37565 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 37565 R-BTA-5432421 https://reactome.org/PathwayBrowser/#/R-BTA-5432421 39S subunit binds 28S subunit:mRNA:fMet-tRNA TAS Bos taurus 37565 R-BTA-5432422 https://reactome.org/PathwayBrowser/#/R-BTA-5432422 Translocation of 55S ribosome by 3 bases in the 3' direction TAS Bos taurus 37565 R-BTA-5432463 https://reactome.org/PathwayBrowser/#/R-BTA-5432463 28S subunit binds MITF2:GTP, mRNA, and formylMet-tRNA TAS Bos taurus 37565 R-BTA-5432551 https://reactome.org/PathwayBrowser/#/R-BTA-5432551 TUFM binds GTP displacing TSFM TAS Bos taurus 37565 R-BTA-5432586 https://reactome.org/PathwayBrowser/#/R-BTA-5432586 TUFM:GTP binds aminoacyl-tRNA TAS Bos taurus 37565 R-BTA-555065 https://reactome.org/PathwayBrowser/#/R-BTA-555065 Formation of clathrin coated vesicle IEA Bos taurus 37565 R-BTA-5578744 https://reactome.org/PathwayBrowser/#/R-BTA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Bos taurus 37565 R-BTA-5610733 https://reactome.org/PathwayBrowser/#/R-BTA-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Bos taurus 37565 R-BTA-5610767 https://reactome.org/PathwayBrowser/#/R-BTA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Bos taurus 37565 R-BTA-5617816 https://reactome.org/PathwayBrowser/#/R-BTA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Bos taurus 37565 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 37565 R-BTA-5618328 https://reactome.org/PathwayBrowser/#/R-BTA-5618328 ATAT acetylates microtubules IEA Bos taurus 37565 R-BTA-5618331 https://reactome.org/PathwayBrowser/#/R-BTA-5618331 HDAC6 deacetylates microtubules IEA Bos taurus 37565 R-BTA-5620914 https://reactome.org/PathwayBrowser/#/R-BTA-5620914 ARF4:GTP binds VxPx-motifs of membrane proteins IEA Bos taurus 37565 R-BTA-5620921 https://reactome.org/PathwayBrowser/#/R-BTA-5620921 ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex IEA Bos taurus 37565 R-BTA-5623508 https://reactome.org/PathwayBrowser/#/R-BTA-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Bos taurus 37565 R-BTA-5623513 https://reactome.org/PathwayBrowser/#/R-BTA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Bos taurus 37565 R-BTA-5623519 https://reactome.org/PathwayBrowser/#/R-BTA-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Bos taurus 37565 R-BTA-5623521 https://reactome.org/PathwayBrowser/#/R-BTA-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Bos taurus 37565 R-BTA-5623524 https://reactome.org/PathwayBrowser/#/R-BTA-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Bos taurus 37565 R-BTA-5623525 https://reactome.org/PathwayBrowser/#/R-BTA-5623525 Cargo-carrying vesicles bud from the TGN IEA Bos taurus 37565 R-BTA-5623527 https://reactome.org/PathwayBrowser/#/R-BTA-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Bos taurus 37565 R-BTA-5623622 https://reactome.org/PathwayBrowser/#/R-BTA-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Bos taurus 37565 R-BTA-5623632 https://reactome.org/PathwayBrowser/#/R-BTA-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Bos taurus 37565 R-BTA-5623667 https://reactome.org/PathwayBrowser/#/R-BTA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Bos taurus 37565 R-BTA-5624126 https://reactome.org/PathwayBrowser/#/R-BTA-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Bos taurus 37565 R-BTA-5624127 https://reactome.org/PathwayBrowser/#/R-BTA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Bos taurus 37565 R-BTA-5625959 https://reactome.org/PathwayBrowser/#/R-BTA-5625959 Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) IEA Bos taurus 37565 R-BTA-5626469 https://reactome.org/PathwayBrowser/#/R-BTA-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Bos taurus 37565 R-BTA-5626507 https://reactome.org/PathwayBrowser/#/R-BTA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Bos taurus 37565 R-BTA-5626549 https://reactome.org/PathwayBrowser/#/R-BTA-5626549 IQGAPs bind CALM1 IEA Bos taurus 37565 R-BTA-5627071 https://reactome.org/PathwayBrowser/#/R-BTA-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane IEA Bos taurus 37565 R-BTA-5627072 https://reactome.org/PathwayBrowser/#/R-BTA-5627072 RHOQ binds GOPC:CFTR IEA Bos taurus 37565 R-BTA-5627775 https://reactome.org/PathwayBrowser/#/R-BTA-5627775 Autophosphorylation of PAK1,2,3 IEA Bos taurus 37565 R-BTA-5638009 https://reactome.org/PathwayBrowser/#/R-BTA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Bos taurus 37565 R-BTA-5638014 https://reactome.org/PathwayBrowser/#/R-BTA-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Bos taurus 37565 R-BTA-5653957 https://reactome.org/PathwayBrowser/#/R-BTA-5653957 Rag dimer formation IEA Bos taurus 37565 R-BTA-5653968 https://reactome.org/PathwayBrowser/#/R-BTA-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Bos taurus 37565 R-BTA-5653974 https://reactome.org/PathwayBrowser/#/R-BTA-5653974 Ragulator binds Rag dimers IEA Bos taurus 37565 R-BTA-5654392 https://reactome.org/PathwayBrowser/#/R-BTA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-5654402 https://reactome.org/PathwayBrowser/#/R-BTA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-5654413 https://reactome.org/PathwayBrowser/#/R-BTA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-5654426 https://reactome.org/PathwayBrowser/#/R-BTA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-5654600 https://reactome.org/PathwayBrowser/#/R-BTA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-5654618 https://reactome.org/PathwayBrowser/#/R-BTA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-5654647 https://reactome.org/PathwayBrowser/#/R-BTA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-5654663 https://reactome.org/PathwayBrowser/#/R-BTA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-5665727 https://reactome.org/PathwayBrowser/#/R-BTA-5665727 FMNL2 binds CDC42:GTP IEA Bos taurus 37565 R-BTA-5665748 https://reactome.org/PathwayBrowser/#/R-BTA-5665748 FMNL2 binds RHOC:GTP IEA Bos taurus 37565 R-BTA-5665751 https://reactome.org/PathwayBrowser/#/R-BTA-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin IEA Bos taurus 37565 R-BTA-5665761 https://reactome.org/PathwayBrowser/#/R-BTA-5665761 FMNL3 binds RHOC:GTP IEA Bos taurus 37565 R-BTA-5665767 https://reactome.org/PathwayBrowser/#/R-BTA-5665767 Activated FMNL3 binds G-actin IEA Bos taurus 37565 R-BTA-5665802 https://reactome.org/PathwayBrowser/#/R-BTA-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Bos taurus 37565 R-BTA-5665809 https://reactome.org/PathwayBrowser/#/R-BTA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Bos taurus 37565 R-BTA-5665989 https://reactome.org/PathwayBrowser/#/R-BTA-5665989 DIAPH1 binds RHOA:GTP IEA Bos taurus 37565 R-BTA-5666088 https://reactome.org/PathwayBrowser/#/R-BTA-5666088 RHOD:GTP recruits DAIPH2-3 to endosomes IEA Bos taurus 37565 R-BTA-5666104 https://reactome.org/PathwayBrowser/#/R-BTA-5666104 RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes IEA Bos taurus 37565 R-BTA-5666129 https://reactome.org/PathwayBrowser/#/R-BTA-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Bos taurus 37565 R-BTA-5666160 https://reactome.org/PathwayBrowser/#/R-BTA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Bos taurus 37565 R-BTA-5666169 https://reactome.org/PathwayBrowser/#/R-BTA-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Bos taurus 37565 R-BTA-5666197 https://reactome.org/PathwayBrowser/#/R-BTA-5666197 RHOA:GTP:RTKN binds LIN7B IEA Bos taurus 37565 R-BTA-5666216 https://reactome.org/PathwayBrowser/#/R-BTA-5666216 RHOA:GTP:RTKN binds TAX1BP3 IEA Bos taurus 37565 R-BTA-5667008 https://reactome.org/PathwayBrowser/#/R-BTA-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Bos taurus 37565 R-BTA-5668605 https://reactome.org/PathwayBrowser/#/R-BTA-5668605 RAC2:GTP binds NOX2 complex IEA Bos taurus 37565 R-BTA-5668629 https://reactome.org/PathwayBrowser/#/R-BTA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Bos taurus 37565 R-BTA-5668714 https://reactome.org/PathwayBrowser/#/R-BTA-5668714 RAC1:GTP binds NOX1 complex IEA Bos taurus 37565 R-BTA-5668718 https://reactome.org/PathwayBrowser/#/R-BTA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 37565 R-BTA-5668731 https://reactome.org/PathwayBrowser/#/R-BTA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 37565 R-BTA-5668735 https://reactome.org/PathwayBrowser/#/R-BTA-5668735 RAC1:GTP binds NOX3 complex IEA Bos taurus 37565 R-BTA-5671970 https://reactome.org/PathwayBrowser/#/R-BTA-5671970 Activated CIT binds KIF14 and PRC1 IEA Bos taurus 37565 R-BTA-5671993 https://reactome.org/PathwayBrowser/#/R-BTA-5671993 CIT-3 binds DLG4 IEA Bos taurus 37565 R-BTA-5672010 https://reactome.org/PathwayBrowser/#/R-BTA-5672010 Active MTORC1 phosphorylates ULK1 IEA Bos taurus 37565 R-BTA-5672017 https://reactome.org/PathwayBrowser/#/R-BTA-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Bos taurus 37565 R-BTA-5672027 https://reactome.org/PathwayBrowser/#/R-BTA-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Bos taurus 37565 R-BTA-5672083 https://reactome.org/PathwayBrowser/#/R-BTA-5672083 KTN1 binds Kinesin-1 IEA Bos taurus 37565 R-BTA-5672304 https://reactome.org/PathwayBrowser/#/R-BTA-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 IEA Bos taurus 37565 R-BTA-5672329 https://reactome.org/PathwayBrowser/#/R-BTA-5672329 IQGAP1 binds CLIP1 and microtubules IEA Bos taurus 37565 R-BTA-5672817 https://reactome.org/PathwayBrowser/#/R-BTA-5672817 Active MTORC1 binds the ULK1 complex IEA Bos taurus 37565 R-BTA-5672824 https://reactome.org/PathwayBrowser/#/R-BTA-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Bos taurus 37565 R-BTA-5672828 https://reactome.org/PathwayBrowser/#/R-BTA-5672828 mTORC1 phosphorylates AKT1S1 IEA Bos taurus 37565 R-BTA-5672843 https://reactome.org/PathwayBrowser/#/R-BTA-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Bos taurus 37565 R-BTA-5672950 https://reactome.org/PathwayBrowser/#/R-BTA-5672950 "Activator" RAF:YWHAB dimer binds RAS:GTP IEA Bos taurus 37565 R-BTA-5672965 https://reactome.org/PathwayBrowser/#/R-BTA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-5672966 https://reactome.org/PathwayBrowser/#/R-BTA-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Bos taurus 37565 R-BTA-5672969 https://reactome.org/PathwayBrowser/#/R-BTA-5672969 Phosphorylation of RAF IEA Bos taurus 37565 R-BTA-5672972 https://reactome.org/PathwayBrowser/#/R-BTA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Bos taurus 37565 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 37565 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 37565 R-BTA-5672980 https://reactome.org/PathwayBrowser/#/R-BTA-5672980 Dissociation of RAS:RAF complex IEA Bos taurus 37565 R-BTA-5673768 https://reactome.org/PathwayBrowser/#/R-BTA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Bos taurus 37565 R-BTA-5674018 https://reactome.org/PathwayBrowser/#/R-BTA-5674018 BRAP binds RAS:GTP IEA Bos taurus 37565 R-BTA-5674022 https://reactome.org/PathwayBrowser/#/R-BTA-5674022 BRAP autoubiquitinates IEA Bos taurus 37565 R-BTA-5675417 https://reactome.org/PathwayBrowser/#/R-BTA-5675417 PEBP1 binds activated RAF1 IEA Bos taurus 37565 R-BTA-5675431 https://reactome.org/PathwayBrowser/#/R-BTA-5675431 PP2A dephosphorylates RAF1 IEA Bos taurus 37565 R-BTA-5675433 https://reactome.org/PathwayBrowser/#/R-BTA-5675433 PP5 dephosphorylates RAF1 S338 IEA Bos taurus 37565 R-BTA-5675790 https://reactome.org/PathwayBrowser/#/R-BTA-5675790 MTORC1 dissociates from ULK complex IEA Bos taurus 37565 R-BTA-5694409 https://reactome.org/PathwayBrowser/#/R-BTA-5694409 Nucleotide exchange on RAB1 IEA Bos taurus 37565 R-BTA-5694417 https://reactome.org/PathwayBrowser/#/R-BTA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Bos taurus 37565 R-BTA-5694418 https://reactome.org/PathwayBrowser/#/R-BTA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Bos taurus 37565 R-BTA-5694441 https://reactome.org/PathwayBrowser/#/R-BTA-5694441 CSNK1D phosphorylates SEC23 IEA Bos taurus 37565 R-BTA-5694522 https://reactome.org/PathwayBrowser/#/R-BTA-5694522 Inner coat assembly and cargo binding IEA Bos taurus 37565 R-BTA-5694527 https://reactome.org/PathwayBrowser/#/R-BTA-5694527 Loss of SAR1B GTPase IEA Bos taurus 37565 R-BTA-5696197 https://reactome.org/PathwayBrowser/#/R-BTA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Bos taurus 37565 R-BTA-6785648 https://reactome.org/PathwayBrowser/#/R-BTA-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Bos taurus 37565 R-BTA-6787533 https://reactome.org/PathwayBrowser/#/R-BTA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Bos taurus 37565 R-BTA-6788611 https://reactome.org/PathwayBrowser/#/R-BTA-6788611 HYKK phosphorylates 5HLYS IEA Bos taurus 37565 R-BTA-6789092 https://reactome.org/PathwayBrowser/#/R-BTA-6789092 NOX2 generates superoxide anion from oxygen IEA Bos taurus 37565 R-BTA-6800138 https://reactome.org/PathwayBrowser/#/R-BTA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Bos taurus 37565 R-BTA-6807864 https://reactome.org/PathwayBrowser/#/R-BTA-6807864 RAB1:GTP recruits GBF1 to the ERGIC IEA Bos taurus 37565 R-BTA-6807866 https://reactome.org/PathwayBrowser/#/R-BTA-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Bos taurus 37565 R-BTA-6807868 https://reactome.org/PathwayBrowser/#/R-BTA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Bos taurus 37565 R-BTA-6807872 https://reactome.org/PathwayBrowser/#/R-BTA-6807872 Active ARF recruits coatomer IEA Bos taurus 37565 R-BTA-6807877 https://reactome.org/PathwayBrowser/#/R-BTA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Bos taurus 37565 R-BTA-6809003 https://reactome.org/PathwayBrowser/#/R-BTA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Bos taurus 37565 R-BTA-6809006 https://reactome.org/PathwayBrowser/#/R-BTA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Bos taurus 37565 R-BTA-6809011 https://reactome.org/PathwayBrowser/#/R-BTA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Bos taurus 37565 R-BTA-6811411 https://reactome.org/PathwayBrowser/#/R-BTA-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Bos taurus 37565 R-BTA-6811412 https://reactome.org/PathwayBrowser/#/R-BTA-6811412 Active ARF recruits coatomer to the Golgi IEA Bos taurus 37565 R-BTA-6811414 https://reactome.org/PathwayBrowser/#/R-BTA-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Bos taurus 37565 R-BTA-6811415 https://reactome.org/PathwayBrowser/#/R-BTA-6811415 RAB:GTP recruits GBF1 to the Golgi membrane IEA Bos taurus 37565 R-BTA-6811417 https://reactome.org/PathwayBrowser/#/R-BTA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Bos taurus 37565 R-BTA-6811418 https://reactome.org/PathwayBrowser/#/R-BTA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Bos taurus 37565 R-BTA-6811423 https://reactome.org/PathwayBrowser/#/R-BTA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Bos taurus 37565 R-BTA-6811426 https://reactome.org/PathwayBrowser/#/R-BTA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Bos taurus 37565 R-BTA-6811427 https://reactome.org/PathwayBrowser/#/R-BTA-6811427 COPI vesicle uncoating at the ER IEA Bos taurus 37565 R-BTA-6811429 https://reactome.org/PathwayBrowser/#/R-BTA-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Bos taurus 37565 R-BTA-6811431 https://reactome.org/PathwayBrowser/#/R-BTA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Bos taurus 37565 R-BTA-6814086 https://reactome.org/PathwayBrowser/#/R-BTA-6814086 ARFRP1 recruits ARL1 to the TGN IEA Bos taurus 37565 R-BTA-6814088 https://reactome.org/PathwayBrowser/#/R-BTA-6814088 SYS1 binds AcM-ARFRP1 IEA Bos taurus 37565 R-BTA-6814091 https://reactome.org/PathwayBrowser/#/R-BTA-6814091 ARL1 recruits TGN Golgin homodimers IEA Bos taurus 37565 R-BTA-6814094 https://reactome.org/PathwayBrowser/#/R-BTA-6814094 ARL1:GTP binds ARFIP2 IEA Bos taurus 37565 R-BTA-6814096 https://reactome.org/PathwayBrowser/#/R-BTA-6814096 ARL1:GTP binds SCOC IEA Bos taurus 37565 R-BTA-6814549 https://reactome.org/PathwayBrowser/#/R-BTA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Bos taurus 37565 R-BTA-6814559 https://reactome.org/PathwayBrowser/#/R-BTA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Bos taurus 37565 R-BTA-6814670 https://reactome.org/PathwayBrowser/#/R-BTA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Bos taurus 37565 R-BTA-6814671 https://reactome.org/PathwayBrowser/#/R-BTA-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Bos taurus 37565 R-BTA-6814674 https://reactome.org/PathwayBrowser/#/R-BTA-6814674 Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins IEA Bos taurus 37565 R-BTA-6814675 https://reactome.org/PathwayBrowser/#/R-BTA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Bos taurus 37565 R-BTA-6814682 https://reactome.org/PathwayBrowser/#/R-BTA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Bos taurus 37565 R-BTA-6814831 https://reactome.org/PathwayBrowser/#/R-BTA-6814831 TBC1D20 binds RAB1:GTP IEA Bos taurus 37565 R-BTA-6814833 https://reactome.org/PathwayBrowser/#/R-BTA-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Bos taurus 37565 R-BTA-70241 https://reactome.org/PathwayBrowser/#/R-BTA-70241 PCK1 phosphorylates OA to yield PEP IEA Bos taurus 37565 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Bos taurus 37565 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Bos taurus 37565 R-BTA-71775 https://reactome.org/PathwayBrowser/#/R-BTA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Bos taurus 37565 R-BTA-72621 https://reactome.org/PathwayBrowser/#/R-BTA-72621 Ribosomal scanning IEA Bos taurus 37565 R-BTA-72663 https://reactome.org/PathwayBrowser/#/R-BTA-72663 De novo formation of eIF2:GTP IEA Bos taurus 37565 R-BTA-72669 https://reactome.org/PathwayBrowser/#/R-BTA-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Bos taurus 37565 R-BTA-72671 https://reactome.org/PathwayBrowser/#/R-BTA-72671 eIF5B:GTP is hydrolyzed and released IEA Bos taurus 37565 R-BTA-72672 https://reactome.org/PathwayBrowser/#/R-BTA-72672 The 60S subunit joins the translation initiation complex IEA Bos taurus 37565 R-BTA-72691 https://reactome.org/PathwayBrowser/#/R-BTA-72691 Formation of the 43S pre-initiation complex IEA Bos taurus 37565 R-BTA-72697 https://reactome.org/PathwayBrowser/#/R-BTA-72697 Start codon recognition IEA Bos taurus 37565 R-BTA-72722 https://reactome.org/PathwayBrowser/#/R-BTA-72722 eIF2 activation IEA Bos taurus 37565 R-BTA-74059 https://reactome.org/PathwayBrowser/#/R-BTA-74059 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 37565 R-BTA-74066 https://reactome.org/PathwayBrowser/#/R-BTA-74066 Gnat1-GTP binds Pde6 and activates it TAS Bos taurus 37565 R-BTA-74885 https://reactome.org/PathwayBrowser/#/R-BTA-74885 GUCYs converts GTP to cGMP IEA Bos taurus 37565 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 37565 R-BTA-749453 https://reactome.org/PathwayBrowser/#/R-BTA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Bos taurus 37565 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 37565 R-BTA-751019 https://reactome.org/PathwayBrowser/#/R-BTA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Bos taurus 37565 R-BTA-751024 https://reactome.org/PathwayBrowser/#/R-BTA-751024 The Ligand:GPCR:Gz complex dissociates IEA Bos taurus 37565 R-BTA-751029 https://reactome.org/PathwayBrowser/#/R-BTA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Bos taurus 37565 R-BTA-77081 https://reactome.org/PathwayBrowser/#/R-BTA-77081 Formation of the CE:GMP intermediate complex IEA Bos taurus 37565 R-BTA-8847887 https://reactome.org/PathwayBrowser/#/R-BTA-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Bos taurus 37565 R-BTA-8848618 https://reactome.org/PathwayBrowser/#/R-BTA-8848618 Activation of RAC1 by the PXN:CRK complex IEA Bos taurus 37565 R-BTA-8849082 https://reactome.org/PathwayBrowser/#/R-BTA-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Bos taurus 37565 R-BTA-8849085 https://reactome.org/PathwayBrowser/#/R-BTA-8849085 ARHGAP35 binds RHOA:GTP IEA Bos taurus 37565 R-BTA-8849348 https://reactome.org/PathwayBrowser/#/R-BTA-8849348 RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo IEA Bos taurus 37565 R-BTA-8849350 https://reactome.org/PathwayBrowser/#/R-BTA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Bos taurus 37565 R-BTA-8849353 https://reactome.org/PathwayBrowser/#/R-BTA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Bos taurus 37565 R-BTA-8849748 https://reactome.org/PathwayBrowser/#/R-BTA-8849748 The COG complex binds RABs at the Golgi membrane IEA Bos taurus 37565 R-BTA-8850041 https://reactome.org/PathwayBrowser/#/R-BTA-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Bos taurus 37565 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 37565 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 37565 R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 37565 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 37565 R-BTA-8851827 https://reactome.org/PathwayBrowser/#/R-BTA-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Bos taurus 37565 R-BTA-8851877 https://reactome.org/PathwayBrowser/#/R-BTA-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Bos taurus 37565 R-BTA-8851899 https://reactome.org/PathwayBrowser/#/R-BTA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Bos taurus 37565 R-BTA-8852280 https://reactome.org/PathwayBrowser/#/R-BTA-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Bos taurus 37565 R-BTA-8852298 https://reactome.org/PathwayBrowser/#/R-BTA-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Bos taurus 37565 R-BTA-8852306 https://reactome.org/PathwayBrowser/#/R-BTA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Bos taurus 37565 R-BTA-8854173 https://reactome.org/PathwayBrowser/#/R-BTA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Bos taurus 37565 R-BTA-8854182 https://reactome.org/PathwayBrowser/#/R-BTA-8854182 TBC1D17 binds OPTN:RAB8A IEA Bos taurus 37565 R-BTA-8854293 https://reactome.org/PathwayBrowser/#/R-BTA-8854293 TBC1D10A (EPI64) binds ARF6:GTP IEA Bos taurus 37565 R-BTA-8854303 https://reactome.org/PathwayBrowser/#/R-BTA-8854303 TBC1D11 binds RAB6 IEA Bos taurus 37565 R-BTA-8854612 https://reactome.org/PathwayBrowser/#/R-BTA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Bos taurus 37565 R-BTA-8856808 https://reactome.org/PathwayBrowser/#/R-BTA-8856808 Recruitment of AP-2 complex and clathrin IEA Bos taurus 37565 R-BTA-8865774 https://reactome.org/PathwayBrowser/#/R-BTA-8865774 TTLLs polyglutamylate tubulin IEA Bos taurus 37565 R-BTA-8867370 https://reactome.org/PathwayBrowser/#/R-BTA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Bos taurus 37565 R-BTA-8868236 https://reactome.org/PathwayBrowser/#/R-BTA-8868236 BAR domain proteins recruit dynamin IEA Bos taurus 37565 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 37565 R-BTA-8868651 https://reactome.org/PathwayBrowser/#/R-BTA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Bos taurus 37565 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 37565 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 37565 R-BTA-8875318 https://reactome.org/PathwayBrowser/#/R-BTA-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Bos taurus 37565 R-BTA-8875320 https://reactome.org/PathwayBrowser/#/R-BTA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Bos taurus 37565 R-BTA-8875568 https://reactome.org/PathwayBrowser/#/R-BTA-8875568 RAPGEF1 activates RAP1 IEA Bos taurus 37565 R-BTA-8875591 https://reactome.org/PathwayBrowser/#/R-BTA-8875591 DOCK7 activates RAC1 IEA Bos taurus 37565 R-BTA-8875659 https://reactome.org/PathwayBrowser/#/R-BTA-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Bos taurus 37565 R-BTA-8875661 https://reactome.org/PathwayBrowser/#/R-BTA-8875661 GGA3 associates with activated MET receptor IEA Bos taurus 37565 R-BTA-8876188 https://reactome.org/PathwayBrowser/#/R-BTA-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Bos taurus 37565 R-BTA-8876190 https://reactome.org/PathwayBrowser/#/R-BTA-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Bos taurus 37565 R-BTA-8876191 https://reactome.org/PathwayBrowser/#/R-BTA-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Bos taurus 37565 R-BTA-8876193 https://reactome.org/PathwayBrowser/#/R-BTA-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Bos taurus 37565 R-BTA-8876454 https://reactome.org/PathwayBrowser/#/R-BTA-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Bos taurus 37565 R-BTA-8876615 https://reactome.org/PathwayBrowser/#/R-BTA-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Bos taurus 37565 R-BTA-8876616 https://reactome.org/PathwayBrowser/#/R-BTA-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Bos taurus 37565 R-BTA-8876837 https://reactome.org/PathwayBrowser/#/R-BTA-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Bos taurus 37565 R-BTA-8877308 https://reactome.org/PathwayBrowser/#/R-BTA-8877308 MADD exchanges GTP for GDP on RAB27 IEA Bos taurus 37565 R-BTA-8877311 https://reactome.org/PathwayBrowser/#/R-BTA-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Bos taurus 37565 R-BTA-8877451 https://reactome.org/PathwayBrowser/#/R-BTA-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Bos taurus 37565 R-BTA-8877475 https://reactome.org/PathwayBrowser/#/R-BTA-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Bos taurus 37565 R-BTA-8877612 https://reactome.org/PathwayBrowser/#/R-BTA-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Bos taurus 37565 R-BTA-8877760 https://reactome.org/PathwayBrowser/#/R-BTA-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Bos taurus 37565 R-BTA-8877813 https://reactome.org/PathwayBrowser/#/R-BTA-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Bos taurus 37565 R-BTA-8877998 https://reactome.org/PathwayBrowser/#/R-BTA-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Bos taurus 37565 R-BTA-8941613 https://reactome.org/PathwayBrowser/#/R-BTA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-8941618 https://reactome.org/PathwayBrowser/#/R-BTA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-8941623 https://reactome.org/PathwayBrowser/#/R-BTA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-8941628 https://reactome.org/PathwayBrowser/#/R-BTA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 37565 R-BTA-8944454 https://reactome.org/PathwayBrowser/#/R-BTA-8944454 mTORC1 phosphorylates MAF1 IEA Bos taurus 37565 R-BTA-8944457 https://reactome.org/PathwayBrowser/#/R-BTA-8944457 MAF1 translocates to the nucleus IEA Bos taurus 37565 R-BTA-8951490 https://reactome.org/PathwayBrowser/#/R-BTA-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Bos taurus 37565 R-BTA-8951498 https://reactome.org/PathwayBrowser/#/R-BTA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Bos taurus 37565 R-BTA-8952716 https://reactome.org/PathwayBrowser/#/R-BTA-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Bos taurus 37565 R-BTA-8952726 https://reactome.org/PathwayBrowser/#/R-BTA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Bos taurus 37565 R-BTA-8955724 https://reactome.org/PathwayBrowser/#/R-BTA-8955724 TTL ligates L-Tyr to the carboxy terminus of alpha-tubulin TAS Bos taurus 37565 R-BTA-8964242 https://reactome.org/PathwayBrowser/#/R-BTA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Bos taurus 37565 R-BTA-8964246 https://reactome.org/PathwayBrowser/#/R-BTA-8964246 BTK in G alpha (12)-BTK complex is activated IEA Bos taurus 37565 R-BTA-8964274 https://reactome.org/PathwayBrowser/#/R-BTA-8964274 G alpha (12) binds BTK IEA Bos taurus 37565 R-BTA-8964280 https://reactome.org/PathwayBrowser/#/R-BTA-8964280 Active Gq binds BTK IEA Bos taurus 37565 R-BTA-8964284 https://reactome.org/PathwayBrowser/#/R-BTA-8964284 BTK in active Gq-BTK complex is activated IEA Bos taurus 37565 R-BTA-8964329 https://reactome.org/PathwayBrowser/#/R-BTA-8964329 G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC IEA Bos taurus 37565 R-BTA-8964333 https://reactome.org/PathwayBrowser/#/R-BTA-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) IEA Bos taurus 37565 R-BTA-8964340 https://reactome.org/PathwayBrowser/#/R-BTA-8964340 Gq-BTK complex dissociates to Active BTK and Gq IEA Bos taurus 37565 R-BTA-8964599 https://reactome.org/PathwayBrowser/#/R-BTA-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Bos taurus 37565 R-BTA-8964604 https://reactome.org/PathwayBrowser/#/R-BTA-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Bos taurus 37565 R-BTA-8964614 https://reactome.org/PathwayBrowser/#/R-BTA-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Bos taurus 37565 R-BTA-8980691 https://reactome.org/PathwayBrowser/#/R-BTA-8980691 RHOA GEFs activate RHOA IEA Bos taurus 37565 R-BTA-8981353 https://reactome.org/PathwayBrowser/#/R-BTA-8981353 RASA1 stimulates RAS GTPase activity IEA Bos taurus 37565 R-BTA-8981355 https://reactome.org/PathwayBrowser/#/R-BTA-8981355 RASA1 binds RAS:GTP IEA Bos taurus 37565 R-BTA-8981637 https://reactome.org/PathwayBrowser/#/R-BTA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Bos taurus 37565 R-BTA-8981892 https://reactome.org/PathwayBrowser/#/R-BTA-8981892 Active G alpha (z) binds RGS proteins IEA Bos taurus 37565 R-BTA-8981926 https://reactome.org/PathwayBrowser/#/R-BTA-8981926 RAC1 and CDC42 activate PAK3 IEA Bos taurus 37565 R-BTA-8981931 https://reactome.org/PathwayBrowser/#/R-BTA-8981931 RAC1 and CDC42 activate PAK2 IEA Bos taurus 37565 R-BTA-8982017 https://reactome.org/PathwayBrowser/#/R-BTA-8982017 Active G alpha (q) binds RGS proteins IEA Bos taurus 37565 R-BTA-8982019 https://reactome.org/PathwayBrowser/#/R-BTA-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Bos taurus 37565 R-BTA-8982020 https://reactome.org/PathwayBrowser/#/R-BTA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Bos taurus 37565 R-BTA-8982021 https://reactome.org/PathwayBrowser/#/R-BTA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Bos taurus 37565 R-BTA-8982025 https://reactome.org/PathwayBrowser/#/R-BTA-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Bos taurus 37565 R-BTA-8982640 https://reactome.org/PathwayBrowser/#/R-BTA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Bos taurus 37565 R-BTA-8985594 https://reactome.org/PathwayBrowser/#/R-BTA-8985594 MYO9B inactivates RHOA IEA Bos taurus 37565 R-BTA-9013004 https://reactome.org/PathwayBrowser/#/R-BTA-9013004 RHOA binds effectors at the ER membrane IEA Bos taurus 37565 R-BTA-9013006 https://reactome.org/PathwayBrowser/#/R-BTA-9013006 RHOA:GTP translocates to the ER membrane IEA Bos taurus 37565 R-BTA-9013009 https://reactome.org/PathwayBrowser/#/R-BTA-9013009 RHOA binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9013109 https://reactome.org/PathwayBrowser/#/R-BTA-9013109 RHOC GEFs activate RHOC IEA Bos taurus 37565 R-BTA-9013110 https://reactome.org/PathwayBrowser/#/R-BTA-9013110 RHOC binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9013111 https://reactome.org/PathwayBrowser/#/R-BTA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Bos taurus 37565 R-BTA-9013143 https://reactome.org/PathwayBrowser/#/R-BTA-9013143 RAC1 GEFs activate RAC1 IEA Bos taurus 37565 R-BTA-9013144 https://reactome.org/PathwayBrowser/#/R-BTA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Bos taurus 37565 R-BTA-9013145 https://reactome.org/PathwayBrowser/#/R-BTA-9013145 RAC1 binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9013159 https://reactome.org/PathwayBrowser/#/R-BTA-9013159 CDC42 GEFs activate CDC42 IEA Bos taurus 37565 R-BTA-9013161 https://reactome.org/PathwayBrowser/#/R-BTA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Bos taurus 37565 R-BTA-9013435 https://reactome.org/PathwayBrowser/#/R-BTA-9013435 RHOD auto-activates IEA Bos taurus 37565 R-BTA-9013437 https://reactome.org/PathwayBrowser/#/R-BTA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Bos taurus 37565 R-BTA-9013438 https://reactome.org/PathwayBrowser/#/R-BTA-9013438 RHOD binds effectors at the endosome membrane IEA Bos taurus 37565 R-BTA-9013452 https://reactome.org/PathwayBrowser/#/R-BTA-9013452 RHOD:GTP translocates to the endosome membrane IEA Bos taurus 37565 R-BTA-9014294 https://reactome.org/PathwayBrowser/#/R-BTA-9014294 RAC2 binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9014295 https://reactome.org/PathwayBrowser/#/R-BTA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Bos taurus 37565 R-BTA-9014296 https://reactome.org/PathwayBrowser/#/R-BTA-9014296 RAC2 GEFs activate RAC2 IEA Bos taurus 37565 R-BTA-9014420 https://reactome.org/PathwayBrowser/#/R-BTA-9014420 RAC2 translocates to the phagocytic vesicle membrane IEA Bos taurus 37565 R-BTA-9014424 https://reactome.org/PathwayBrowser/#/R-BTA-9014424 RAC2 binds effectors at the phagocytic vesicle membrane IEA Bos taurus 37565 R-BTA-9014433 https://reactome.org/PathwayBrowser/#/R-BTA-9014433 RHOG GEFs activate RHOG IEA Bos taurus 37565 R-BTA-9014434 https://reactome.org/PathwayBrowser/#/R-BTA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Bos taurus 37565 R-BTA-9014449 https://reactome.org/PathwayBrowser/#/R-BTA-9014449 RHOG binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9014454 https://reactome.org/PathwayBrowser/#/R-BTA-9014454 RHOG translocates to the ER membrane IEA Bos taurus 37565 R-BTA-9014467 https://reactome.org/PathwayBrowser/#/R-BTA-9014467 RHOG binds effectors at the ER membrane IEA Bos taurus 37565 R-BTA-9017488 https://reactome.org/PathwayBrowser/#/R-BTA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Bos taurus 37565 R-BTA-9017491 https://reactome.org/PathwayBrowser/#/R-BTA-9017491 RHOJ GEFs activate RHOJ IEA Bos taurus 37565 R-BTA-9018745 https://reactome.org/PathwayBrowser/#/R-BTA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Bos taurus 37565 R-BTA-9018746 https://reactome.org/PathwayBrowser/#/R-BTA-9018746 RHOQ binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9018747 https://reactome.org/PathwayBrowser/#/R-BTA-9018747 RHOQ GEFs activate RHOQ IEA Bos taurus 37565 R-BTA-9018754 https://reactome.org/PathwayBrowser/#/R-BTA-9018754 GDIs bind RHOH IEA Bos taurus 37565 R-BTA-9018756 https://reactome.org/PathwayBrowser/#/R-BTA-9018756 RHOH binds GTP IEA Bos taurus 37565 R-BTA-9018758 https://reactome.org/PathwayBrowser/#/R-BTA-9018758 RHOH binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9018766 https://reactome.org/PathwayBrowser/#/R-BTA-9018766 RHOU binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9018768 https://reactome.org/PathwayBrowser/#/R-BTA-9018768 RHOU auto-activates IEA Bos taurus 37565 R-BTA-9018774 https://reactome.org/PathwayBrowser/#/R-BTA-9018774 RHOBTB1 binds GTP IEA Bos taurus 37565 R-BTA-9018778 https://reactome.org/PathwayBrowser/#/R-BTA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Bos taurus 37565 R-BTA-9018785 https://reactome.org/PathwayBrowser/#/R-BTA-9018785 RHOBTB2 binds GTP IEA Bos taurus 37565 R-BTA-9018787 https://reactome.org/PathwayBrowser/#/R-BTA-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Bos taurus 37565 R-BTA-9018794 https://reactome.org/PathwayBrowser/#/R-BTA-9018794 RHOV binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9018798 https://reactome.org/PathwayBrowser/#/R-BTA-9018798 RHOV binds GTP IEA Bos taurus 37565 R-BTA-9018804 https://reactome.org/PathwayBrowser/#/R-BTA-9018804 RAC3 GEFs activate RAC3 IEA Bos taurus 37565 R-BTA-9018806 https://reactome.org/PathwayBrowser/#/R-BTA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Bos taurus 37565 R-BTA-9018808 https://reactome.org/PathwayBrowser/#/R-BTA-9018808 RAC3 binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9018814 https://reactome.org/PathwayBrowser/#/R-BTA-9018814 RHOT1 hydrolyzes GTP IEA Bos taurus 37565 R-BTA-9018815 https://reactome.org/PathwayBrowser/#/R-BTA-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Bos taurus 37565 R-BTA-9018824 https://reactome.org/PathwayBrowser/#/R-BTA-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Bos taurus 37565 R-BTA-9018826 https://reactome.org/PathwayBrowser/#/R-BTA-9018826 RHOT2 hydrolyzes GTP IEA Bos taurus 37565 R-BTA-9018836 https://reactome.org/PathwayBrowser/#/R-BTA-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Bos taurus 37565 R-BTA-9032798 https://reactome.org/PathwayBrowser/#/R-BTA-9032798 DOCK3 activates RAC1 IEA Bos taurus 37565 R-BTA-939265 https://reactome.org/PathwayBrowser/#/R-BTA-939265 Activation of Rap1 by membrane-associated GEFs IEA Bos taurus 37565 R-BTA-947535 https://reactome.org/PathwayBrowser/#/R-BTA-947535 Cyclisation of GTP to precursor Z IEA Bos taurus 37565 R-BTA-9607304 https://reactome.org/PathwayBrowser/#/R-BTA-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Bos taurus 37565 R-BTA-9610152 https://reactome.org/PathwayBrowser/#/R-BTA-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Bos taurus 37565 R-BTA-9610153 https://reactome.org/PathwayBrowser/#/R-BTA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Bos taurus 37565 R-BTA-9610154 https://reactome.org/PathwayBrowser/#/R-BTA-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Bos taurus 37565 R-BTA-9610156 https://reactome.org/PathwayBrowser/#/R-BTA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Bos taurus 37565 R-BTA-9610163 https://reactome.org/PathwayBrowser/#/R-BTA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Bos taurus 37565 R-BTA-9624845 https://reactome.org/PathwayBrowser/#/R-BTA-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Bos taurus 37565 R-BTA-9624876 https://reactome.org/PathwayBrowser/#/R-BTA-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Bos taurus 37565 R-BTA-9624893 https://reactome.org/PathwayBrowser/#/R-BTA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Bos taurus 37565 R-BTA-9626848 https://reactome.org/PathwayBrowser/#/R-BTA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Bos taurus 37565 R-BTA-9632910 https://reactome.org/PathwayBrowser/#/R-BTA-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Bos taurus 37565 R-BTA-9632918 https://reactome.org/PathwayBrowser/#/R-BTA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Bos taurus 37565 R-BTA-9639286 https://reactome.org/PathwayBrowser/#/R-BTA-9639286 RRAGC,D exchanges GTP for GDP IEA Bos taurus 37565 R-BTA-9640167 https://reactome.org/PathwayBrowser/#/R-BTA-9640167 RRAGA,B exchanges GDP for GTP IEA Bos taurus 37565 R-BTA-9640168 https://reactome.org/PathwayBrowser/#/R-BTA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Bos taurus 37565 R-BTA-9640195 https://reactome.org/PathwayBrowser/#/R-BTA-9640195 RRAGA,B hydrolyzes GTP IEA Bos taurus 37565 R-BTA-9645598 https://reactome.org/PathwayBrowser/#/R-BTA-9645598 RRAGC,D hydrolyzes GTP IEA Bos taurus 37565 R-BTA-9645608 https://reactome.org/PathwayBrowser/#/R-BTA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Bos taurus 37565 R-BTA-9646468 https://reactome.org/PathwayBrowser/#/R-BTA-9646468 mTORC1 binds RHEB:GTP IEA Bos taurus 37565 R-BTA-9646679 https://reactome.org/PathwayBrowser/#/R-BTA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Bos taurus 37565 R-BTA-9646685 https://reactome.org/PathwayBrowser/#/R-BTA-9646685 Aggresome dissociates from dynein and microtubule IEA Bos taurus 37565 R-BTA-9648017 https://reactome.org/PathwayBrowser/#/R-BTA-9648017 EML4 binds to microtubules IEA Bos taurus 37565 R-BTA-9648114 https://reactome.org/PathwayBrowser/#/R-BTA-9648114 EML4 recruits NUDC to mitotic spindle IEA Bos taurus 37565 R-BTA-9649735 https://reactome.org/PathwayBrowser/#/R-BTA-9649735 Intrinsic nucleotide exchange on RAS IEA Bos taurus 37565 R-BTA-9649736 https://reactome.org/PathwayBrowser/#/R-BTA-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Bos taurus 37565 R-BTA-9653108 https://reactome.org/PathwayBrowser/#/R-BTA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Bos taurus 37565 R-BTA-9654523 https://reactome.org/PathwayBrowser/#/R-BTA-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Bos taurus 37565 R-BTA-9654533 https://reactome.org/PathwayBrowser/#/R-BTA-9654533 KRAS4B recycles to the plasma membrane IEA Bos taurus 37565 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus 37565 R-BTA-9657603 https://reactome.org/PathwayBrowser/#/R-BTA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Bos taurus 37565 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 37565 R-BTA-9657608 https://reactome.org/PathwayBrowser/#/R-BTA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Bos taurus 37565 R-BTA-9658253 https://reactome.org/PathwayBrowser/#/R-BTA-9658253 RAS:GTP binds PI3K IEA Bos taurus 37565 R-BTA-9658445 https://reactome.org/PathwayBrowser/#/R-BTA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Bos taurus 37565 R-BTA-9660557 https://reactome.org/PathwayBrowser/#/R-BTA-9660557 RAS:GTP binds RAL GDS proteins IEA Bos taurus 37565 R-BTA-9668419 https://reactome.org/PathwayBrowser/#/R-BTA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Bos taurus 37565 R-BTA-9691168 https://reactome.org/PathwayBrowser/#/R-BTA-9691168 RAC1 translocates to the endoplasmic reticulum membrane IEA Bos taurus 37565 R-BTA-9691174 https://reactome.org/PathwayBrowser/#/R-BTA-9691174 RAC1 binds effectors at the ER membrane IEA Bos taurus 37565 R-BTA-9692800 https://reactome.org/PathwayBrowser/#/R-BTA-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Bos taurus 37565 R-BTA-9692809 https://reactome.org/PathwayBrowser/#/R-BTA-9692809 CDC42 binds effectors at the ER membrane IEA Bos taurus 37565 R-BTA-9693111 https://reactome.org/PathwayBrowser/#/R-BTA-9693111 RHOF auto-activates IEA Bos taurus 37565 R-BTA-9693125 https://reactome.org/PathwayBrowser/#/R-BTA-9693125 RHOF binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9693198 https://reactome.org/PathwayBrowser/#/R-BTA-9693198 RHOD binds effectors at the plasma membrane IEA Bos taurus 37565 R-BTA-9693207 https://reactome.org/PathwayBrowser/#/R-BTA-9693207 RHOD translocates to the mitochondrial outer membrane IEA Bos taurus 37565 R-BTA-9693214 https://reactome.org/PathwayBrowser/#/R-BTA-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Bos taurus 37565 R-BTA-9693243 https://reactome.org/PathwayBrowser/#/R-BTA-9693243 RHOD translocates to the Golgi membrane IEA Bos taurus 37565 R-BTA-9693250 https://reactome.org/PathwayBrowser/#/R-BTA-9693250 RHOD binds effectors at the Golgi membrane IEA Bos taurus 37565 R-BTA-9693282 https://reactome.org/PathwayBrowser/#/R-BTA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Bos taurus 37565 R-BTA-9696266 https://reactome.org/PathwayBrowser/#/R-BTA-9696266 RND2 binds effectors IEA Bos taurus 37565 R-BTA-9696267 https://reactome.org/PathwayBrowser/#/R-BTA-9696267 RND3 binds GTP IEA Bos taurus 37565 R-BTA-9696268 https://reactome.org/PathwayBrowser/#/R-BTA-9696268 RND3 binds effectors IEA Bos taurus 37565 R-BTA-9696271 https://reactome.org/PathwayBrowser/#/R-BTA-9696271 RND1 binds effectors IEA Bos taurus 37565 R-BTA-9696274 https://reactome.org/PathwayBrowser/#/R-BTA-9696274 RND1 binds GTP IEA Bos taurus 37565 R-BTA-9696275 https://reactome.org/PathwayBrowser/#/R-BTA-9696275 RND2 binds GTP IEA Bos taurus 37565 R-BTA-9714361 https://reactome.org/PathwayBrowser/#/R-BTA-9714361 RHOC activates endoplasmic reticulum effectors IEA Bos taurus 37565 R-BTA-9714363 https://reactome.org/PathwayBrowser/#/R-BTA-9714363 RHOC translocates to the endoplasmic reticulum membrane IEA Bos taurus 37565 R-BTA-9714477 https://reactome.org/PathwayBrowser/#/R-BTA-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Bos taurus 37565 R-BTA-9714480 https://reactome.org/PathwayBrowser/#/R-BTA-9714480 RAC2 translocates to the mitochondrial membrane IEA Bos taurus 37565 R-BTA-9714481 https://reactome.org/PathwayBrowser/#/R-BTA-9714481 RAC2 binds effectors at the ER membrane IEA Bos taurus 37565 R-BTA-9714483 https://reactome.org/PathwayBrowser/#/R-BTA-9714483 RAC2 translocates to the ER membrane IEA Bos taurus 37565 R-BTA-9714691 https://reactome.org/PathwayBrowser/#/R-BTA-9714691 RAC3 binds ER effectors IEA Bos taurus 37565 R-BTA-9714694 https://reactome.org/PathwayBrowser/#/R-BTA-9714694 RAC3 translocates to the endoplasmic reticulum membrane IEA Bos taurus 37565 R-BTA-983259 https://reactome.org/PathwayBrowser/#/R-BTA-983259 Kinesins move along microtubules consuming ATP IEA Bos taurus 37565 R-BTA-983266 https://reactome.org/PathwayBrowser/#/R-BTA-983266 Kinesins bind microtubules IEA Bos taurus 37565 R-BTA-983422 https://reactome.org/PathwayBrowser/#/R-BTA-983422 Disassembly of COPII coated vesicle IEA Bos taurus 37565 R-BTA-983424 https://reactome.org/PathwayBrowser/#/R-BTA-983424 Budding of COPII coated vesicle IEA Bos taurus 37565 R-BTA-983425 https://reactome.org/PathwayBrowser/#/R-BTA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Bos taurus 37565 R-CEL-111524 https://reactome.org/PathwayBrowser/#/R-CEL-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Caenorhabditis elegans 37565 R-CEL-111879 https://reactome.org/PathwayBrowser/#/R-CEL-111879 PIP2 hydrolysis IEA Caenorhabditis elegans 37565 R-CEL-112037 https://reactome.org/PathwayBrowser/#/R-CEL-112037 Inactivation of PLC beta IEA Caenorhabditis elegans 37565 R-CEL-114542 https://reactome.org/PathwayBrowser/#/R-CEL-114542 RAC1,RAC2,RHOG activate PI3K IEA Caenorhabditis elegans 37565 R-CEL-114544 https://reactome.org/PathwayBrowser/#/R-CEL-114544 p115-RhoGEF activation of RHOA IEA Caenorhabditis elegans 37565 R-CEL-114548 https://reactome.org/PathwayBrowser/#/R-CEL-114548 G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) IEA Caenorhabditis elegans 37565 R-CEL-114552 https://reactome.org/PathwayBrowser/#/R-CEL-114552 Thrombin-activated PARs activate G12/13 IEA Caenorhabditis elegans 37565 R-CEL-114558 https://reactome.org/PathwayBrowser/#/R-CEL-114558 Thrombin-activated PARs activate Gq IEA Caenorhabditis elegans 37565 R-CEL-114688 https://reactome.org/PathwayBrowser/#/R-CEL-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Caenorhabditis elegans 37565 R-CEL-1168636 https://reactome.org/PathwayBrowser/#/R-CEL-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Caenorhabditis elegans 37565 R-CEL-1306972 https://reactome.org/PathwayBrowser/#/R-CEL-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Caenorhabditis elegans 37565 R-CEL-1433415 https://reactome.org/PathwayBrowser/#/R-CEL-1433415 Activation of RAC1 IEA Caenorhabditis elegans 37565 R-CEL-1433471 https://reactome.org/PathwayBrowser/#/R-CEL-1433471 Activation of RAS by p-KIT bound SOS1 IEA Caenorhabditis elegans 37565 R-CEL-1474146 https://reactome.org/PathwayBrowser/#/R-CEL-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Caenorhabditis elegans 37565 R-CEL-156808 https://reactome.org/PathwayBrowser/#/R-CEL-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Caenorhabditis elegans 37565 R-CEL-156823 https://reactome.org/PathwayBrowser/#/R-CEL-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Caenorhabditis elegans 37565 R-CEL-156930 https://reactome.org/PathwayBrowser/#/R-CEL-156930 GTP-binding activates eEF2 IEA Caenorhabditis elegans 37565 R-CEL-157849 https://reactome.org/PathwayBrowser/#/R-CEL-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Caenorhabditis elegans 37565 R-CEL-165195 https://reactome.org/PathwayBrowser/#/R-CEL-165195 GTP loading by Rheb IEA Caenorhabditis elegans 37565 R-CEL-165680 https://reactome.org/PathwayBrowser/#/R-CEL-165680 Formation of active mTORC1 complex IEA Caenorhabditis elegans 37565 R-CEL-165718 https://reactome.org/PathwayBrowser/#/R-CEL-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Caenorhabditis elegans 37565 R-CEL-167415 https://reactome.org/PathwayBrowser/#/R-CEL-167415 G-protein alpha subunit is inactivated IEA Caenorhabditis elegans 37565 R-CEL-167429 https://reactome.org/PathwayBrowser/#/R-CEL-167429 The receptor:G-protein complex binds GTP IEA Caenorhabditis elegans 37565 R-CEL-170026 https://reactome.org/PathwayBrowser/#/R-CEL-170026 Protons are translocated from the intermembrane space to the matrix IEA Caenorhabditis elegans 37565 R-CEL-170666 https://reactome.org/PathwayBrowser/#/R-CEL-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Caenorhabditis elegans 37565 R-CEL-170671 https://reactome.org/PathwayBrowser/#/R-CEL-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Caenorhabditis elegans 37565 R-CEL-170672 https://reactome.org/PathwayBrowser/#/R-CEL-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Caenorhabditis elegans 37565 R-CEL-170676 https://reactome.org/PathwayBrowser/#/R-CEL-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Caenorhabditis elegans 37565 R-CEL-170685 https://reactome.org/PathwayBrowser/#/R-CEL-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Caenorhabditis elegans 37565 R-CEL-170686 https://reactome.org/PathwayBrowser/#/R-CEL-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Caenorhabditis elegans 37565 R-CEL-170986 https://reactome.org/PathwayBrowser/#/R-CEL-170986 Ral-GDS binds to Ras-GTP IEA Caenorhabditis elegans 37565 R-CEL-177938 https://reactome.org/PathwayBrowser/#/R-CEL-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Caenorhabditis elegans 37565 R-CEL-177945 https://reactome.org/PathwayBrowser/#/R-CEL-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Caenorhabditis elegans 37565 R-CEL-183002 https://reactome.org/PathwayBrowser/#/R-CEL-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Caenorhabditis elegans 37565 R-CEL-183084 https://reactome.org/PathwayBrowser/#/R-CEL-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Caenorhabditis elegans 37565 R-CEL-183094 https://reactome.org/PathwayBrowser/#/R-CEL-183094 CDC42:GTP binds CBL:Beta-Pix IEA Caenorhabditis elegans 37565 R-CEL-186834 https://reactome.org/PathwayBrowser/#/R-CEL-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Caenorhabditis elegans 37565 R-CEL-194518 https://reactome.org/PathwayBrowser/#/R-CEL-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Caenorhabditis elegans 37565 R-CEL-2029454 https://reactome.org/PathwayBrowser/#/R-CEL-2029454 Autophosphorylation of PAK1 IEA Caenorhabditis elegans 37565 R-CEL-2029456 https://reactome.org/PathwayBrowser/#/R-CEL-2029456 RAC1 and CDC42 activate PAK1 IEA Caenorhabditis elegans 37565 R-CEL-2029466 https://reactome.org/PathwayBrowser/#/R-CEL-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Caenorhabditis elegans 37565 R-CEL-2029469 https://reactome.org/PathwayBrowser/#/R-CEL-2029469 p-ERK phosphorylates WAVEs and ABI IEA Caenorhabditis elegans 37565 R-CEL-203973 https://reactome.org/PathwayBrowser/#/R-CEL-203973 Vesicle budding IEA Caenorhabditis elegans 37565 R-CEL-203977 https://reactome.org/PathwayBrowser/#/R-CEL-203977 SAR1 Activation And Membrane Binding IEA Caenorhabditis elegans 37565 R-CEL-203979 https://reactome.org/PathwayBrowser/#/R-CEL-203979 Coat Assembly IEA Caenorhabditis elegans 37565 R-CEL-205039 https://reactome.org/PathwayBrowser/#/R-CEL-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Caenorhabditis elegans 37565 R-CEL-205136 https://reactome.org/PathwayBrowser/#/R-CEL-205136 GTP-bound RAC contributes to JNK activation IEA Caenorhabditis elegans 37565 R-CEL-2065539 https://reactome.org/PathwayBrowser/#/R-CEL-2065539 SREBP1A,1C,2:Importin beta-1 dissociates IEA Caenorhabditis elegans 37565 R-CEL-2130194 https://reactome.org/PathwayBrowser/#/R-CEL-2130194 ABL phosphorylates WAVEs IEA Caenorhabditis elegans 37565 R-CEL-2179407 https://reactome.org/PathwayBrowser/#/R-CEL-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Caenorhabditis elegans 37565 R-CEL-2197690 https://reactome.org/PathwayBrowser/#/R-CEL-2197690 Detachment of WASP/WAVE IEA Caenorhabditis elegans 37565 R-CEL-2197698 https://reactome.org/PathwayBrowser/#/R-CEL-2197698 Src phosphorylate WASP,N-WASP IEA Caenorhabditis elegans 37565 R-CEL-2214351 https://reactome.org/PathwayBrowser/#/R-CEL-2214351 PLK1 phosphorylates GORASP1 IEA Caenorhabditis elegans 37565 R-CEL-2316434 https://reactome.org/PathwayBrowser/#/R-CEL-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 37565 R-CEL-2422927 https://reactome.org/PathwayBrowser/#/R-CEL-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Caenorhabditis elegans 37565 R-CEL-350769 https://reactome.org/PathwayBrowser/#/R-CEL-350769 trans-Golgi Network Coat Activation IEA Caenorhabditis elegans 37565 R-CEL-354060 https://reactome.org/PathwayBrowser/#/R-CEL-354060 Translocation of RIAM to plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-354066 https://reactome.org/PathwayBrowser/#/R-CEL-354066 Translocation of PTK2 to Focal complexes IEA Caenorhabditis elegans 37565 R-CEL-354073 https://reactome.org/PathwayBrowser/#/R-CEL-354073 Autophosphorylation of PTK2 at Y397 IEA Caenorhabditis elegans 37565 R-CEL-354077 https://reactome.org/PathwayBrowser/#/R-CEL-354077 Integrin alphaIIb beta3 activation IEA Caenorhabditis elegans 37565 R-CEL-354087 https://reactome.org/PathwayBrowser/#/R-CEL-354087 Recruitment of GRB2 to p-PTK2 IEA Caenorhabditis elegans 37565 R-CEL-354097 https://reactome.org/PathwayBrowser/#/R-CEL-354097 Activation of Talin IEA Caenorhabditis elegans 37565 R-CEL-354124 https://reactome.org/PathwayBrowser/#/R-CEL-354124 Phosphorylation of pPTK2 by SRC IEA Caenorhabditis elegans 37565 R-CEL-354149 https://reactome.org/PathwayBrowser/#/R-CEL-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Caenorhabditis elegans 37565 R-CEL-354165 https://reactome.org/PathwayBrowser/#/R-CEL-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Caenorhabditis elegans 37565 R-CEL-354173 https://reactome.org/PathwayBrowser/#/R-CEL-354173 Activation of Rap1 by cytosolic GEFs IEA Caenorhabditis elegans 37565 R-CEL-372819 https://reactome.org/PathwayBrowser/#/R-CEL-372819 PCK2 phosphorylates OA to yield PEP IEA Caenorhabditis elegans 37565 R-CEL-377186 https://reactome.org/PathwayBrowser/#/R-CEL-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Caenorhabditis elegans 37565 R-CEL-377640 https://reactome.org/PathwayBrowser/#/R-CEL-377640 Autophosphorylation of SRC IEA Caenorhabditis elegans 37565 R-CEL-377641 https://reactome.org/PathwayBrowser/#/R-CEL-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Caenorhabditis elegans 37565 R-CEL-377644 https://reactome.org/PathwayBrowser/#/R-CEL-377644 Release of CSK from SRC IEA Caenorhabditis elegans 37565 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 37565 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 37565 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 37565 R-CEL-380979 https://reactome.org/PathwayBrowser/#/R-CEL-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Caenorhabditis elegans 37565 R-CEL-381727 https://reactome.org/PathwayBrowser/#/R-CEL-381727 RAP1A exchanges GDP for GTP IEA Caenorhabditis elegans 37565 R-CEL-3858475 https://reactome.org/PathwayBrowser/#/R-CEL-3858475 ppDVL recruits RAC IEA Caenorhabditis elegans 37565 R-CEL-3858495 https://reactome.org/PathwayBrowser/#/R-CEL-3858495 DAAM1 recruits GTP-bound RHOA IEA Caenorhabditis elegans 37565 R-CEL-389788 https://reactome.org/PathwayBrowser/#/R-CEL-389788 Activation of PAKs by RAC1 and CDC42 IEA Caenorhabditis elegans 37565 R-CEL-392054 https://reactome.org/PathwayBrowser/#/R-CEL-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Caenorhabditis elegans 37565 R-CEL-392064 https://reactome.org/PathwayBrowser/#/R-CEL-392064 G alpha (z) inhibits adenylate cyclase IEA Caenorhabditis elegans 37565 R-CEL-392195 https://reactome.org/PathwayBrowser/#/R-CEL-392195 Gi activation by P2Y purinoceptor 12 IEA Caenorhabditis elegans 37565 R-CEL-392513 https://reactome.org/PathwayBrowser/#/R-CEL-392513 Rap1 signal termination by Rap1GAPs IEA Caenorhabditis elegans 37565 R-CEL-392835 https://reactome.org/PathwayBrowser/#/R-CEL-392835 Rap1 sequesters Raf1 to inhibit ERK cascade IEA Caenorhabditis elegans 37565 R-CEL-3928576 https://reactome.org/PathwayBrowser/#/R-CEL-3928576 RHOA:GTP binds ROCK, activating it IEA Caenorhabditis elegans 37565 R-CEL-3928592 https://reactome.org/PathwayBrowser/#/R-CEL-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Caenorhabditis elegans 37565 R-CEL-3928595 https://reactome.org/PathwayBrowser/#/R-CEL-3928595 N-WASP binds ARP2/3 and G-actin IEA Caenorhabditis elegans 37565 R-CEL-3928601 https://reactome.org/PathwayBrowser/#/R-CEL-3928601 CDC42 and PIP2 bind WASL, activating it IEA Caenorhabditis elegans 37565 R-CEL-3928612 https://reactome.org/PathwayBrowser/#/R-CEL-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 37565 R-CEL-3928619 https://reactome.org/PathwayBrowser/#/R-CEL-3928619 PAK1 binds RAC1:GTP IEA Caenorhabditis elegans 37565 R-CEL-3928620 https://reactome.org/PathwayBrowser/#/R-CEL-3928620 PAK1 autophosphorylates IEA Caenorhabditis elegans 37565 R-CEL-3928625 https://reactome.org/PathwayBrowser/#/R-CEL-3928625 PAKs autophosphorylate IEA Caenorhabditis elegans 37565 R-CEL-3928628 https://reactome.org/PathwayBrowser/#/R-CEL-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 37565 R-CEL-3928633 https://reactome.org/PathwayBrowser/#/R-CEL-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Caenorhabditis elegans 37565 R-CEL-3928640 https://reactome.org/PathwayBrowser/#/R-CEL-3928640 PAKs phosphorylate MLC IEA Caenorhabditis elegans 37565 R-CEL-3928641 https://reactome.org/PathwayBrowser/#/R-CEL-3928641 PAK binds RAC and bPIX IEA Caenorhabditis elegans 37565 R-CEL-3928642 https://reactome.org/PathwayBrowser/#/R-CEL-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 37565 R-CEL-3928647 https://reactome.org/PathwayBrowser/#/R-CEL-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Caenorhabditis elegans 37565 R-CEL-3928651 https://reactome.org/PathwayBrowser/#/R-CEL-3928651 NGEF exchanges GTP for GDP on RHOA IEA Caenorhabditis elegans 37565 R-CEL-3965444 https://reactome.org/PathwayBrowser/#/R-CEL-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-3965447 https://reactome.org/PathwayBrowser/#/R-CEL-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Caenorhabditis elegans 37565 R-CEL-397835 https://reactome.org/PathwayBrowser/#/R-CEL-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Caenorhabditis elegans 37565 R-CEL-397891 https://reactome.org/PathwayBrowser/#/R-CEL-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Caenorhabditis elegans 37565 R-CEL-398184 https://reactome.org/PathwayBrowser/#/R-CEL-398184 LARG activation by G alpha 12/13 IEA Caenorhabditis elegans 37565 R-CEL-398185 https://reactome.org/PathwayBrowser/#/R-CEL-398185 LARG binds plexin B1 IEA Caenorhabditis elegans 37565 R-CEL-399930 https://reactome.org/PathwayBrowser/#/R-CEL-399930 Activation of PAK by Rac1 IEA Caenorhabditis elegans 37565 R-CEL-399939 https://reactome.org/PathwayBrowser/#/R-CEL-399939 Autophosphorylation of PAK IEA Caenorhabditis elegans 37565 R-CEL-400037 https://reactome.org/PathwayBrowser/#/R-CEL-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Caenorhabditis elegans 37565 R-CEL-400092 https://reactome.org/PathwayBrowser/#/R-CEL-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Caenorhabditis elegans 37565 R-CEL-400586 https://reactome.org/PathwayBrowser/#/R-CEL-400586 G alpha (q) binds to Trio family RhoGEFs IEA Caenorhabditis elegans 37565 R-CEL-400682 https://reactome.org/PathwayBrowser/#/R-CEL-400682 Active Rac1 interacts with Plexin-B1:Sema4D IEA Caenorhabditis elegans 37565 R-CEL-4093336 https://reactome.org/PathwayBrowser/#/R-CEL-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 37565 R-CEL-4093339 https://reactome.org/PathwayBrowser/#/R-CEL-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Caenorhabditis elegans 37565 R-CEL-416358 https://reactome.org/PathwayBrowser/#/R-CEL-416358 G alpha (q) inhibits PI3K alpha IEA Caenorhabditis elegans 37565 R-CEL-416516 https://reactome.org/PathwayBrowser/#/R-CEL-416516 GRK2 sequesters activated Gq IEA Caenorhabditis elegans 37565 R-CEL-416546 https://reactome.org/PathwayBrowser/#/R-CEL-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Caenorhabditis elegans 37565 R-CEL-416559 https://reactome.org/PathwayBrowser/#/R-CEL-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Caenorhabditis elegans 37565 R-CEL-416562 https://reactome.org/PathwayBrowser/#/R-CEL-416562 p190RhoGAP binds Plexin-B1 IEA Caenorhabditis elegans 37565 R-CEL-416588 https://reactome.org/PathwayBrowser/#/R-CEL-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Caenorhabditis elegans 37565 R-CEL-418574 https://reactome.org/PathwayBrowser/#/R-CEL-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Caenorhabditis elegans 37565 R-CEL-418582 https://reactome.org/PathwayBrowser/#/R-CEL-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Caenorhabditis elegans 37565 R-CEL-418850 https://reactome.org/PathwayBrowser/#/R-CEL-418850 Activation of Cdc42 IEA Caenorhabditis elegans 37565 R-CEL-418856 https://reactome.org/PathwayBrowser/#/R-CEL-418856 Activation of Rac1 IEA Caenorhabditis elegans 37565 R-CEL-419049 https://reactome.org/PathwayBrowser/#/R-CEL-419049 ROCK activation by RHO IEA Caenorhabditis elegans 37565 R-CEL-419166 https://reactome.org/PathwayBrowser/#/R-CEL-419166 GEFs activate RhoA,B,C IEA Caenorhabditis elegans 37565 R-CEL-420883 https://reactome.org/PathwayBrowser/#/R-CEL-420883 Opsins act as GEFs for G alpha-t IEA Caenorhabditis elegans 37565 R-CEL-421690 https://reactome.org/PathwayBrowser/#/R-CEL-421690 Recruitment of ABLIM to the plasma membrane TAS Caenorhabditis elegans 37565 R-CEL-421831 https://reactome.org/PathwayBrowser/#/R-CEL-421831 trans-Golgi Network Coat Assembly IEA Caenorhabditis elegans 37565 R-CEL-421835 https://reactome.org/PathwayBrowser/#/R-CEL-421835 trans-Golgi Network Vesicle Scission IEA Caenorhabditis elegans 37565 R-CEL-428750 https://reactome.org/PathwayBrowser/#/R-CEL-428750 Gq activation by TP receptor IEA Caenorhabditis elegans 37565 R-CEL-428917 https://reactome.org/PathwayBrowser/#/R-CEL-428917 G13 activation by TP receptor IEA Caenorhabditis elegans 37565 R-CEL-428941 https://reactome.org/PathwayBrowser/#/R-CEL-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Caenorhabditis elegans 37565 R-CEL-429415 https://reactome.org/PathwayBrowser/#/R-CEL-429415 SYK binds to integrin alphaIIb beta3 IEA Caenorhabditis elegans 37565 R-CEL-429441 https://reactome.org/PathwayBrowser/#/R-CEL-429441 SYK activation by SRC IEA Caenorhabditis elegans 37565 R-CEL-432706 https://reactome.org/PathwayBrowser/#/R-CEL-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Caenorhabditis elegans 37565 R-CEL-432707 https://reactome.org/PathwayBrowser/#/R-CEL-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Caenorhabditis elegans 37565 R-CEL-442273 https://reactome.org/PathwayBrowser/#/R-CEL-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Caenorhabditis elegans 37565 R-CEL-442291 https://reactome.org/PathwayBrowser/#/R-CEL-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Caenorhabditis elegans 37565 R-CEL-442314 https://reactome.org/PathwayBrowser/#/R-CEL-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Caenorhabditis elegans 37565 R-CEL-443905 https://reactome.org/PathwayBrowser/#/R-CEL-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Caenorhabditis elegans 37565 R-CEL-445064 https://reactome.org/PathwayBrowser/#/R-CEL-445064 Activation of Rac1 by VAV2 IEA Caenorhabditis elegans 37565 R-CEL-445072 https://reactome.org/PathwayBrowser/#/R-CEL-445072 Interaction of PAK1 with Rac1-GTP IEA Caenorhabditis elegans 37565 R-CEL-447074 https://reactome.org/PathwayBrowser/#/R-CEL-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Caenorhabditis elegans 37565 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 37565 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 37565 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 37565 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 37565 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 37565 R-CEL-5218804 https://reactome.org/PathwayBrowser/#/R-CEL-5218804 p38 MAPK activation by VEGFR IEA Caenorhabditis elegans 37565 R-CEL-5218812 https://reactome.org/PathwayBrowser/#/R-CEL-5218812 FYN phosphorylates PAK2 IEA Caenorhabditis elegans 37565 R-CEL-5218814 https://reactome.org/PathwayBrowser/#/R-CEL-5218814 PAK2 autophorylates IEA Caenorhabditis elegans 37565 R-CEL-5218832 https://reactome.org/PathwayBrowser/#/R-CEL-5218832 CDC42:GTP binds PAK2 IEA Caenorhabditis elegans 37565 R-CEL-5218850 https://reactome.org/PathwayBrowser/#/R-CEL-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 37565 R-CEL-5228992 https://reactome.org/PathwayBrowser/#/R-CEL-5228992 ROCK1,ROCK2 are activated IEA Caenorhabditis elegans 37565 R-CEL-5357445 https://reactome.org/PathwayBrowser/#/R-CEL-5357445 PAK1-3 dimer disassociates IEA Caenorhabditis elegans 37565 R-CEL-5357472 https://reactome.org/PathwayBrowser/#/R-CEL-5357472 PAK1-3 autophosphorylates IEA Caenorhabditis elegans 37565 R-CEL-5357483 https://reactome.org/PathwayBrowser/#/R-CEL-5357483 RAC1 binds PAK1-3 IEA Caenorhabditis elegans 37565 R-CEL-5419261 https://reactome.org/PathwayBrowser/#/R-CEL-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Caenorhabditis elegans 37565 R-CEL-5419264 https://reactome.org/PathwayBrowser/#/R-CEL-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Caenorhabditis elegans 37565 R-CEL-5419271 https://reactome.org/PathwayBrowser/#/R-CEL-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Caenorhabditis elegans 37565 R-CEL-5419273 https://reactome.org/PathwayBrowser/#/R-CEL-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Caenorhabditis elegans 37565 R-CEL-555065 https://reactome.org/PathwayBrowser/#/R-CEL-555065 Formation of clathrin coated vesicle IEA Caenorhabditis elegans 37565 R-CEL-5623519 https://reactome.org/PathwayBrowser/#/R-CEL-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Caenorhabditis elegans 37565 R-CEL-5623521 https://reactome.org/PathwayBrowser/#/R-CEL-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Caenorhabditis elegans 37565 R-CEL-5623524 https://reactome.org/PathwayBrowser/#/R-CEL-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Caenorhabditis elegans 37565 R-CEL-5623525 https://reactome.org/PathwayBrowser/#/R-CEL-5623525 Cargo-carrying vesicles bud from the TGN IEA Caenorhabditis elegans 37565 R-CEL-5623527 https://reactome.org/PathwayBrowser/#/R-CEL-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Caenorhabditis elegans 37565 R-CEL-5623622 https://reactome.org/PathwayBrowser/#/R-CEL-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Caenorhabditis elegans 37565 R-CEL-5623632 https://reactome.org/PathwayBrowser/#/R-CEL-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Caenorhabditis elegans 37565 R-CEL-5623667 https://reactome.org/PathwayBrowser/#/R-CEL-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Caenorhabditis elegans 37565 R-CEL-5624126 https://reactome.org/PathwayBrowser/#/R-CEL-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Caenorhabditis elegans 37565 R-CEL-5624127 https://reactome.org/PathwayBrowser/#/R-CEL-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Caenorhabditis elegans 37565 R-CEL-5624486 https://reactome.org/PathwayBrowser/#/R-CEL-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Caenorhabditis elegans 37565 R-CEL-5624492 https://reactome.org/PathwayBrowser/#/R-CEL-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Caenorhabditis elegans 37565 R-CEL-5624494 https://reactome.org/PathwayBrowser/#/R-CEL-5624494 RAF1 binds p21 RAS:GTP IEA Caenorhabditis elegans 37565 R-CEL-5626469 https://reactome.org/PathwayBrowser/#/R-CEL-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Caenorhabditis elegans 37565 R-CEL-5626507 https://reactome.org/PathwayBrowser/#/R-CEL-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Caenorhabditis elegans 37565 R-CEL-5626549 https://reactome.org/PathwayBrowser/#/R-CEL-5626549 IQGAPs bind CALM1 IEA Caenorhabditis elegans 37565 R-CEL-5627071 https://reactome.org/PathwayBrowser/#/R-CEL-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-5627072 https://reactome.org/PathwayBrowser/#/R-CEL-5627072 RHOQ binds GOPC:CFTR IEA Caenorhabditis elegans 37565 R-CEL-5627775 https://reactome.org/PathwayBrowser/#/R-CEL-5627775 Autophosphorylation of PAK1,2,3 IEA Caenorhabditis elegans 37565 R-CEL-5638014 https://reactome.org/PathwayBrowser/#/R-CEL-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Caenorhabditis elegans 37565 R-CEL-5653957 https://reactome.org/PathwayBrowser/#/R-CEL-5653957 Rag dimer formation IEA Caenorhabditis elegans 37565 R-CEL-5653968 https://reactome.org/PathwayBrowser/#/R-CEL-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Caenorhabditis elegans 37565 R-CEL-5654392 https://reactome.org/PathwayBrowser/#/R-CEL-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-5654402 https://reactome.org/PathwayBrowser/#/R-CEL-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-5654413 https://reactome.org/PathwayBrowser/#/R-CEL-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-5654426 https://reactome.org/PathwayBrowser/#/R-CEL-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-5654600 https://reactome.org/PathwayBrowser/#/R-CEL-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-5654618 https://reactome.org/PathwayBrowser/#/R-CEL-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-5654647 https://reactome.org/PathwayBrowser/#/R-CEL-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-5654663 https://reactome.org/PathwayBrowser/#/R-CEL-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-5665727 https://reactome.org/PathwayBrowser/#/R-CEL-5665727 FMNL2 binds CDC42:GTP IEA Caenorhabditis elegans 37565 R-CEL-5665802 https://reactome.org/PathwayBrowser/#/R-CEL-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Caenorhabditis elegans 37565 R-CEL-5665989 https://reactome.org/PathwayBrowser/#/R-CEL-5665989 DIAPH1 binds RHOA:GTP IEA Caenorhabditis elegans 37565 R-CEL-5666070 https://reactome.org/PathwayBrowser/#/R-CEL-5666070 RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes IEA Caenorhabditis elegans 37565 R-CEL-5666088 https://reactome.org/PathwayBrowser/#/R-CEL-5666088 RHOD:GTP recruits DAIPH2-3 to endosomes IEA Caenorhabditis elegans 37565 R-CEL-5666104 https://reactome.org/PathwayBrowser/#/R-CEL-5666104 RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes IEA Caenorhabditis elegans 37565 R-CEL-5666197 https://reactome.org/PathwayBrowser/#/R-CEL-5666197 RHOA:GTP:RTKN binds LIN7B IEA Caenorhabditis elegans 37565 R-CEL-5666216 https://reactome.org/PathwayBrowser/#/R-CEL-5666216 RHOA:GTP:RTKN binds TAX1BP3 IEA Caenorhabditis elegans 37565 R-CEL-5672010 https://reactome.org/PathwayBrowser/#/R-CEL-5672010 Active MTORC1 phosphorylates ULK1 IEA Caenorhabditis elegans 37565 R-CEL-5672017 https://reactome.org/PathwayBrowser/#/R-CEL-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Caenorhabditis elegans 37565 R-CEL-5672817 https://reactome.org/PathwayBrowser/#/R-CEL-5672817 Active MTORC1 binds the ULK1 complex IEA Caenorhabditis elegans 37565 R-CEL-5672824 https://reactome.org/PathwayBrowser/#/R-CEL-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Caenorhabditis elegans 37565 R-CEL-5672828 https://reactome.org/PathwayBrowser/#/R-CEL-5672828 mTORC1 phosphorylates AKT1S1 IEA Caenorhabditis elegans 37565 R-CEL-5672950 https://reactome.org/PathwayBrowser/#/R-CEL-5672950 "Activator" RAF:YWHAB dimer binds RAS:GTP IEA Caenorhabditis elegans 37565 R-CEL-5672965 https://reactome.org/PathwayBrowser/#/R-CEL-5672965 RAS GEFs promote RAS nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-5672966 https://reactome.org/PathwayBrowser/#/R-CEL-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Caenorhabditis elegans 37565 R-CEL-5672972 https://reactome.org/PathwayBrowser/#/R-CEL-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Caenorhabditis elegans 37565 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 37565 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 37565 R-CEL-5672980 https://reactome.org/PathwayBrowser/#/R-CEL-5672980 Dissociation of RAS:RAF complex IEA Caenorhabditis elegans 37565 R-CEL-5673768 https://reactome.org/PathwayBrowser/#/R-CEL-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Caenorhabditis elegans 37565 R-CEL-5674018 https://reactome.org/PathwayBrowser/#/R-CEL-5674018 BRAP binds RAS:GTP IEA Caenorhabditis elegans 37565 R-CEL-5674022 https://reactome.org/PathwayBrowser/#/R-CEL-5674022 BRAP autoubiquitinates IEA Caenorhabditis elegans 37565 R-CEL-5675417 https://reactome.org/PathwayBrowser/#/R-CEL-5675417 PEBP1 binds activated RAF1 IEA Caenorhabditis elegans 37565 R-CEL-5675431 https://reactome.org/PathwayBrowser/#/R-CEL-5675431 PP2A dephosphorylates RAF1 IEA Caenorhabditis elegans 37565 R-CEL-5675433 https://reactome.org/PathwayBrowser/#/R-CEL-5675433 PP5 dephosphorylates RAF1 S338 IEA Caenorhabditis elegans 37565 R-CEL-5675790 https://reactome.org/PathwayBrowser/#/R-CEL-5675790 MTORC1 dissociates from ULK complex IEA Caenorhabditis elegans 37565 R-CEL-5694409 https://reactome.org/PathwayBrowser/#/R-CEL-5694409 Nucleotide exchange on RAB1 IEA Caenorhabditis elegans 37565 R-CEL-5694417 https://reactome.org/PathwayBrowser/#/R-CEL-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Caenorhabditis elegans 37565 R-CEL-5694418 https://reactome.org/PathwayBrowser/#/R-CEL-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Caenorhabditis elegans 37565 R-CEL-5694522 https://reactome.org/PathwayBrowser/#/R-CEL-5694522 Inner coat assembly and cargo binding IEA Caenorhabditis elegans 37565 R-CEL-5694527 https://reactome.org/PathwayBrowser/#/R-CEL-5694527 Loss of SAR1B GTPase IEA Caenorhabditis elegans 37565 R-CEL-5696197 https://reactome.org/PathwayBrowser/#/R-CEL-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Caenorhabditis elegans 37565 R-CEL-6785648 https://reactome.org/PathwayBrowser/#/R-CEL-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Caenorhabditis elegans 37565 R-CEL-6787533 https://reactome.org/PathwayBrowser/#/R-CEL-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Caenorhabditis elegans 37565 R-CEL-6800138 https://reactome.org/PathwayBrowser/#/R-CEL-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Caenorhabditis elegans 37565 R-CEL-6807864 https://reactome.org/PathwayBrowser/#/R-CEL-6807864 RAB1:GTP recruits GBF1 to the ERGIC IEA Caenorhabditis elegans 37565 R-CEL-6807868 https://reactome.org/PathwayBrowser/#/R-CEL-6807868 GBF1 stimulates ARF nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-6807872 https://reactome.org/PathwayBrowser/#/R-CEL-6807872 Active ARF recruits coatomer IEA Caenorhabditis elegans 37565 R-CEL-6809003 https://reactome.org/PathwayBrowser/#/R-CEL-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Caenorhabditis elegans 37565 R-CEL-6809011 https://reactome.org/PathwayBrowser/#/R-CEL-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Caenorhabditis elegans 37565 R-CEL-6811415 https://reactome.org/PathwayBrowser/#/R-CEL-6811415 RAB:GTP recruits GBF1 to the Golgi membrane IEA Caenorhabditis elegans 37565 R-CEL-6811417 https://reactome.org/PathwayBrowser/#/R-CEL-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Caenorhabditis elegans 37565 R-CEL-6811426 https://reactome.org/PathwayBrowser/#/R-CEL-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Caenorhabditis elegans 37565 R-CEL-6811427 https://reactome.org/PathwayBrowser/#/R-CEL-6811427 COPI vesicle uncoating at the ER IEA Caenorhabditis elegans 37565 R-CEL-6811429 https://reactome.org/PathwayBrowser/#/R-CEL-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Caenorhabditis elegans 37565 R-CEL-6814086 https://reactome.org/PathwayBrowser/#/R-CEL-6814086 ARFRP1 recruits ARL1 to the TGN IEA Caenorhabditis elegans 37565 R-CEL-6814088 https://reactome.org/PathwayBrowser/#/R-CEL-6814088 SYS1 binds AcM-ARFRP1 IEA Caenorhabditis elegans 37565 R-CEL-6814091 https://reactome.org/PathwayBrowser/#/R-CEL-6814091 ARL1 recruits TGN Golgin homodimers IEA Caenorhabditis elegans 37565 R-CEL-6814094 https://reactome.org/PathwayBrowser/#/R-CEL-6814094 ARL1:GTP binds ARFIP2 IEA Caenorhabditis elegans 37565 R-CEL-6814096 https://reactome.org/PathwayBrowser/#/R-CEL-6814096 ARL1:GTP binds SCOC IEA Caenorhabditis elegans 37565 R-CEL-6814559 https://reactome.org/PathwayBrowser/#/R-CEL-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Caenorhabditis elegans 37565 R-CEL-6814831 https://reactome.org/PathwayBrowser/#/R-CEL-6814831 TBC1D20 binds RAB1:GTP IEA Caenorhabditis elegans 37565 R-CEL-6814833 https://reactome.org/PathwayBrowser/#/R-CEL-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Caenorhabditis elegans 37565 R-CEL-70241 https://reactome.org/PathwayBrowser/#/R-CEL-70241 PCK1 phosphorylates OA to yield PEP IEA Caenorhabditis elegans 37565 R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Caenorhabditis elegans 37565 R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Caenorhabditis elegans 37565 R-CEL-71775 https://reactome.org/PathwayBrowser/#/R-CEL-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Caenorhabditis elegans 37565 R-CEL-72621 https://reactome.org/PathwayBrowser/#/R-CEL-72621 Ribosomal scanning IEA Caenorhabditis elegans 37565 R-CEL-72663 https://reactome.org/PathwayBrowser/#/R-CEL-72663 De novo formation of eIF2:GTP IEA Caenorhabditis elegans 37565 R-CEL-72669 https://reactome.org/PathwayBrowser/#/R-CEL-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Caenorhabditis elegans 37565 R-CEL-72671 https://reactome.org/PathwayBrowser/#/R-CEL-72671 eIF5B:GTP is hydrolyzed and released IEA Caenorhabditis elegans 37565 R-CEL-72672 https://reactome.org/PathwayBrowser/#/R-CEL-72672 The 60S subunit joins the translation initiation complex IEA Caenorhabditis elegans 37565 R-CEL-72691 https://reactome.org/PathwayBrowser/#/R-CEL-72691 Formation of the 43S pre-initiation complex IEA Caenorhabditis elegans 37565 R-CEL-72697 https://reactome.org/PathwayBrowser/#/R-CEL-72697 Start codon recognition IEA Caenorhabditis elegans 37565 R-CEL-72722 https://reactome.org/PathwayBrowser/#/R-CEL-72722 eIF2 activation IEA Caenorhabditis elegans 37565 R-CEL-74885 https://reactome.org/PathwayBrowser/#/R-CEL-74885 GUCYs converts GTP to cGMP IEA Caenorhabditis elegans 37565 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 37565 R-CEL-749453 https://reactome.org/PathwayBrowser/#/R-CEL-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Caenorhabditis elegans 37565 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 37565 R-CEL-751019 https://reactome.org/PathwayBrowser/#/R-CEL-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Caenorhabditis elegans 37565 R-CEL-751024 https://reactome.org/PathwayBrowser/#/R-CEL-751024 The Ligand:GPCR:Gz complex dissociates IEA Caenorhabditis elegans 37565 R-CEL-751029 https://reactome.org/PathwayBrowser/#/R-CEL-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Caenorhabditis elegans 37565 R-CEL-77081 https://reactome.org/PathwayBrowser/#/R-CEL-77081 Formation of the CE:GMP intermediate complex IEA Caenorhabditis elegans 37565 R-CEL-8847534 https://reactome.org/PathwayBrowser/#/R-CEL-8847534 RAB43 hydrolyses GTP IEA Caenorhabditis elegans 37565 R-CEL-8847537 https://reactome.org/PathwayBrowser/#/R-CEL-8847537 RAB43:GTP binds USP8NL IEA Caenorhabditis elegans 37565 R-CEL-8847887 https://reactome.org/PathwayBrowser/#/R-CEL-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Caenorhabditis elegans 37565 R-CEL-8848618 https://reactome.org/PathwayBrowser/#/R-CEL-8848618 Activation of RAC1 by the PXN:CRK complex IEA Caenorhabditis elegans 37565 R-CEL-8849082 https://reactome.org/PathwayBrowser/#/R-CEL-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-8849085 https://reactome.org/PathwayBrowser/#/R-CEL-8849085 ARHGAP35 binds RHOA:GTP IEA Caenorhabditis elegans 37565 R-CEL-8849348 https://reactome.org/PathwayBrowser/#/R-CEL-8849348 RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo IEA Caenorhabditis elegans 37565 R-CEL-8849350 https://reactome.org/PathwayBrowser/#/R-CEL-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Caenorhabditis elegans 37565 R-CEL-8849353 https://reactome.org/PathwayBrowser/#/R-CEL-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Caenorhabditis elegans 37565 R-CEL-8849748 https://reactome.org/PathwayBrowser/#/R-CEL-8849748 The COG complex binds RABs at the Golgi membrane IEA Caenorhabditis elegans 37565 R-CEL-8850041 https://reactome.org/PathwayBrowser/#/R-CEL-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Caenorhabditis elegans 37565 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 37565 R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 37565 R-CEL-8851827 https://reactome.org/PathwayBrowser/#/R-CEL-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Caenorhabditis elegans 37565 R-CEL-8851877 https://reactome.org/PathwayBrowser/#/R-CEL-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Caenorhabditis elegans 37565 R-CEL-8851899 https://reactome.org/PathwayBrowser/#/R-CEL-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Caenorhabditis elegans 37565 R-CEL-8854173 https://reactome.org/PathwayBrowser/#/R-CEL-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Caenorhabditis elegans 37565 R-CEL-8854293 https://reactome.org/PathwayBrowser/#/R-CEL-8854293 TBC1D10A (EPI64) binds ARF6:GTP IEA Caenorhabditis elegans 37565 R-CEL-8854303 https://reactome.org/PathwayBrowser/#/R-CEL-8854303 TBC1D11 binds RAB6 IEA Caenorhabditis elegans 37565 R-CEL-8854612 https://reactome.org/PathwayBrowser/#/R-CEL-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Caenorhabditis elegans 37565 R-CEL-8868236 https://reactome.org/PathwayBrowser/#/R-CEL-8868236 BAR domain proteins recruit dynamin IEA Caenorhabditis elegans 37565 R-CEL-8868648 https://reactome.org/PathwayBrowser/#/R-CEL-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Caenorhabditis elegans 37565 R-CEL-8868651 https://reactome.org/PathwayBrowser/#/R-CEL-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Caenorhabditis elegans 37565 R-CEL-8868661 https://reactome.org/PathwayBrowser/#/R-CEL-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Caenorhabditis elegans 37565 R-CEL-8875318 https://reactome.org/PathwayBrowser/#/R-CEL-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Caenorhabditis elegans 37565 R-CEL-8875320 https://reactome.org/PathwayBrowser/#/R-CEL-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Caenorhabditis elegans 37565 R-CEL-8875568 https://reactome.org/PathwayBrowser/#/R-CEL-8875568 RAPGEF1 activates RAP1 IEA Caenorhabditis elegans 37565 R-CEL-8875591 https://reactome.org/PathwayBrowser/#/R-CEL-8875591 DOCK7 activates RAC1 IEA Caenorhabditis elegans 37565 R-CEL-8875659 https://reactome.org/PathwayBrowser/#/R-CEL-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-8875661 https://reactome.org/PathwayBrowser/#/R-CEL-8875661 GGA3 associates with activated MET receptor IEA Caenorhabditis elegans 37565 R-CEL-8876188 https://reactome.org/PathwayBrowser/#/R-CEL-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Caenorhabditis elegans 37565 R-CEL-8876190 https://reactome.org/PathwayBrowser/#/R-CEL-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Caenorhabditis elegans 37565 R-CEL-8876193 https://reactome.org/PathwayBrowser/#/R-CEL-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Caenorhabditis elegans 37565 R-CEL-8876615 https://reactome.org/PathwayBrowser/#/R-CEL-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Caenorhabditis elegans 37565 R-CEL-8876616 https://reactome.org/PathwayBrowser/#/R-CEL-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Caenorhabditis elegans 37565 R-CEL-8876837 https://reactome.org/PathwayBrowser/#/R-CEL-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Caenorhabditis elegans 37565 R-CEL-8877308 https://reactome.org/PathwayBrowser/#/R-CEL-8877308 MADD exchanges GTP for GDP on RAB27 IEA Caenorhabditis elegans 37565 R-CEL-8877451 https://reactome.org/PathwayBrowser/#/R-CEL-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Caenorhabditis elegans 37565 R-CEL-8877475 https://reactome.org/PathwayBrowser/#/R-CEL-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Caenorhabditis elegans 37565 R-CEL-8877612 https://reactome.org/PathwayBrowser/#/R-CEL-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Caenorhabditis elegans 37565 R-CEL-8877813 https://reactome.org/PathwayBrowser/#/R-CEL-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Caenorhabditis elegans 37565 R-CEL-8877998 https://reactome.org/PathwayBrowser/#/R-CEL-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Caenorhabditis elegans 37565 R-CEL-8944454 https://reactome.org/PathwayBrowser/#/R-CEL-8944454 mTORC1 phosphorylates MAF1 IEA Caenorhabditis elegans 37565 R-CEL-8944457 https://reactome.org/PathwayBrowser/#/R-CEL-8944457 MAF1 translocates to the nucleus IEA Caenorhabditis elegans 37565 R-CEL-8951490 https://reactome.org/PathwayBrowser/#/R-CEL-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Caenorhabditis elegans 37565 R-CEL-8952726 https://reactome.org/PathwayBrowser/#/R-CEL-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Caenorhabditis elegans 37565 R-CEL-8964242 https://reactome.org/PathwayBrowser/#/R-CEL-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Caenorhabditis elegans 37565 R-CEL-8964329 https://reactome.org/PathwayBrowser/#/R-CEL-8964329 G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC IEA Caenorhabditis elegans 37565 R-CEL-8964599 https://reactome.org/PathwayBrowser/#/R-CEL-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Caenorhabditis elegans 37565 R-CEL-8964604 https://reactome.org/PathwayBrowser/#/R-CEL-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Caenorhabditis elegans 37565 R-CEL-8964614 https://reactome.org/PathwayBrowser/#/R-CEL-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Caenorhabditis elegans 37565 R-CEL-8980691 https://reactome.org/PathwayBrowser/#/R-CEL-8980691 RHOA GEFs activate RHOA IEA Caenorhabditis elegans 37565 R-CEL-8981637 https://reactome.org/PathwayBrowser/#/R-CEL-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-8981892 https://reactome.org/PathwayBrowser/#/R-CEL-8981892 Active G alpha (z) binds RGS proteins IEA Caenorhabditis elegans 37565 R-CEL-8981926 https://reactome.org/PathwayBrowser/#/R-CEL-8981926 RAC1 and CDC42 activate PAK3 IEA Caenorhabditis elegans 37565 R-CEL-8981931 https://reactome.org/PathwayBrowser/#/R-CEL-8981931 RAC1 and CDC42 activate PAK2 IEA Caenorhabditis elegans 37565 R-CEL-8982017 https://reactome.org/PathwayBrowser/#/R-CEL-8982017 Active G alpha (q) binds RGS proteins IEA Caenorhabditis elegans 37565 R-CEL-8982019 https://reactome.org/PathwayBrowser/#/R-CEL-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Caenorhabditis elegans 37565 R-CEL-8982020 https://reactome.org/PathwayBrowser/#/R-CEL-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Caenorhabditis elegans 37565 R-CEL-8982021 https://reactome.org/PathwayBrowser/#/R-CEL-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Caenorhabditis elegans 37565 R-CEL-8982025 https://reactome.org/PathwayBrowser/#/R-CEL-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Caenorhabditis elegans 37565 R-CEL-8985594 https://reactome.org/PathwayBrowser/#/R-CEL-8985594 MYO9B inactivates RHOA IEA Caenorhabditis elegans 37565 R-CEL-9013006 https://reactome.org/PathwayBrowser/#/R-CEL-9013006 RHOA:GTP translocates to the ER membrane IEA Caenorhabditis elegans 37565 R-CEL-9013009 https://reactome.org/PathwayBrowser/#/R-CEL-9013009 RHOA binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9013022 https://reactome.org/PathwayBrowser/#/R-CEL-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-9013023 https://reactome.org/PathwayBrowser/#/R-CEL-9013023 RHOB GEFs activate RHOB IEA Caenorhabditis elegans 37565 R-CEL-9013024 https://reactome.org/PathwayBrowser/#/R-CEL-9013024 RHOB binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9013143 https://reactome.org/PathwayBrowser/#/R-CEL-9013143 RAC1 GEFs activate RAC1 IEA Caenorhabditis elegans 37565 R-CEL-9013144 https://reactome.org/PathwayBrowser/#/R-CEL-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-9013145 https://reactome.org/PathwayBrowser/#/R-CEL-9013145 RAC1 binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9013159 https://reactome.org/PathwayBrowser/#/R-CEL-9013159 CDC42 GEFs activate CDC42 IEA Caenorhabditis elegans 37565 R-CEL-9013161 https://reactome.org/PathwayBrowser/#/R-CEL-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-9013435 https://reactome.org/PathwayBrowser/#/R-CEL-9013435 RHOD auto-activates IEA Caenorhabditis elegans 37565 R-CEL-9013437 https://reactome.org/PathwayBrowser/#/R-CEL-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-9013438 https://reactome.org/PathwayBrowser/#/R-CEL-9013438 RHOD binds effectors at the endosome membrane IEA Caenorhabditis elegans 37565 R-CEL-9013452 https://reactome.org/PathwayBrowser/#/R-CEL-9013452 RHOD:GTP translocates to the endosome membrane IEA Caenorhabditis elegans 37565 R-CEL-9014294 https://reactome.org/PathwayBrowser/#/R-CEL-9014294 RAC2 binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9014295 https://reactome.org/PathwayBrowser/#/R-CEL-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-9014296 https://reactome.org/PathwayBrowser/#/R-CEL-9014296 RAC2 GEFs activate RAC2 IEA Caenorhabditis elegans 37565 R-CEL-9014420 https://reactome.org/PathwayBrowser/#/R-CEL-9014420 RAC2 translocates to the phagocytic vesicle membrane IEA Caenorhabditis elegans 37565 R-CEL-9014433 https://reactome.org/PathwayBrowser/#/R-CEL-9014433 RHOG GEFs activate RHOG IEA Caenorhabditis elegans 37565 R-CEL-9014434 https://reactome.org/PathwayBrowser/#/R-CEL-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-9014449 https://reactome.org/PathwayBrowser/#/R-CEL-9014449 RHOG binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9014454 https://reactome.org/PathwayBrowser/#/R-CEL-9014454 RHOG translocates to the ER membrane IEA Caenorhabditis elegans 37565 R-CEL-9017488 https://reactome.org/PathwayBrowser/#/R-CEL-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-9017491 https://reactome.org/PathwayBrowser/#/R-CEL-9017491 RHOJ GEFs activate RHOJ IEA Caenorhabditis elegans 37565 R-CEL-9018745 https://reactome.org/PathwayBrowser/#/R-CEL-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-9018746 https://reactome.org/PathwayBrowser/#/R-CEL-9018746 RHOQ binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9018747 https://reactome.org/PathwayBrowser/#/R-CEL-9018747 RHOQ GEFs activate RHOQ IEA Caenorhabditis elegans 37565 R-CEL-9018754 https://reactome.org/PathwayBrowser/#/R-CEL-9018754 GDIs bind RHOH IEA Caenorhabditis elegans 37565 R-CEL-9018756 https://reactome.org/PathwayBrowser/#/R-CEL-9018756 RHOH binds GTP IEA Caenorhabditis elegans 37565 R-CEL-9018758 https://reactome.org/PathwayBrowser/#/R-CEL-9018758 RHOH binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9018766 https://reactome.org/PathwayBrowser/#/R-CEL-9018766 RHOU binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9018768 https://reactome.org/PathwayBrowser/#/R-CEL-9018768 RHOU auto-activates IEA Caenorhabditis elegans 37565 R-CEL-9018794 https://reactome.org/PathwayBrowser/#/R-CEL-9018794 RHOV binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9018798 https://reactome.org/PathwayBrowser/#/R-CEL-9018798 RHOV binds GTP IEA Caenorhabditis elegans 37565 R-CEL-9018804 https://reactome.org/PathwayBrowser/#/R-CEL-9018804 RAC3 GEFs activate RAC3 IEA Caenorhabditis elegans 37565 R-CEL-9018806 https://reactome.org/PathwayBrowser/#/R-CEL-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-9018808 https://reactome.org/PathwayBrowser/#/R-CEL-9018808 RAC3 binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9018814 https://reactome.org/PathwayBrowser/#/R-CEL-9018814 RHOT1 hydrolyzes GTP IEA Caenorhabditis elegans 37565 R-CEL-9018815 https://reactome.org/PathwayBrowser/#/R-CEL-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Caenorhabditis elegans 37565 R-CEL-9018824 https://reactome.org/PathwayBrowser/#/R-CEL-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Caenorhabditis elegans 37565 R-CEL-9018826 https://reactome.org/PathwayBrowser/#/R-CEL-9018826 RHOT2 hydrolyzes GTP IEA Caenorhabditis elegans 37565 R-CEL-9018836 https://reactome.org/PathwayBrowser/#/R-CEL-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Caenorhabditis elegans 37565 R-CEL-939265 https://reactome.org/PathwayBrowser/#/R-CEL-939265 Activation of Rap1 by membrane-associated GEFs IEA Caenorhabditis elegans 37565 R-CEL-947535 https://reactome.org/PathwayBrowser/#/R-CEL-947535 Cyclisation of GTP to precursor Z IEA Caenorhabditis elegans 37565 R-CEL-9607304 https://reactome.org/PathwayBrowser/#/R-CEL-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Caenorhabditis elegans 37565 R-CEL-9610152 https://reactome.org/PathwayBrowser/#/R-CEL-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Caenorhabditis elegans 37565 R-CEL-9610153 https://reactome.org/PathwayBrowser/#/R-CEL-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Caenorhabditis elegans 37565 R-CEL-9610154 https://reactome.org/PathwayBrowser/#/R-CEL-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Caenorhabditis elegans 37565 R-CEL-9610156 https://reactome.org/PathwayBrowser/#/R-CEL-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Caenorhabditis elegans 37565 R-CEL-9610163 https://reactome.org/PathwayBrowser/#/R-CEL-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Caenorhabditis elegans 37565 R-CEL-9624845 https://reactome.org/PathwayBrowser/#/R-CEL-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Caenorhabditis elegans 37565 R-CEL-9624876 https://reactome.org/PathwayBrowser/#/R-CEL-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Caenorhabditis elegans 37565 R-CEL-9624893 https://reactome.org/PathwayBrowser/#/R-CEL-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Caenorhabditis elegans 37565 R-CEL-9632910 https://reactome.org/PathwayBrowser/#/R-CEL-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Caenorhabditis elegans 37565 R-CEL-9632918 https://reactome.org/PathwayBrowser/#/R-CEL-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Caenorhabditis elegans 37565 R-CEL-9639286 https://reactome.org/PathwayBrowser/#/R-CEL-9639286 RRAGC,D exchanges GTP for GDP IEA Caenorhabditis elegans 37565 R-CEL-9640167 https://reactome.org/PathwayBrowser/#/R-CEL-9640167 RRAGA,B exchanges GDP for GTP IEA Caenorhabditis elegans 37565 R-CEL-9640168 https://reactome.org/PathwayBrowser/#/R-CEL-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Caenorhabditis elegans 37565 R-CEL-9640195 https://reactome.org/PathwayBrowser/#/R-CEL-9640195 RRAGA,B hydrolyzes GTP IEA Caenorhabditis elegans 37565 R-CEL-9645598 https://reactome.org/PathwayBrowser/#/R-CEL-9645598 RRAGC,D hydrolyzes GTP IEA Caenorhabditis elegans 37565 R-CEL-9645608 https://reactome.org/PathwayBrowser/#/R-CEL-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Caenorhabditis elegans 37565 R-CEL-9646468 https://reactome.org/PathwayBrowser/#/R-CEL-9646468 mTORC1 binds RHEB:GTP IEA Caenorhabditis elegans 37565 R-CEL-9649735 https://reactome.org/PathwayBrowser/#/R-CEL-9649735 Intrinsic nucleotide exchange on RAS IEA Caenorhabditis elegans 37565 R-CEL-9649736 https://reactome.org/PathwayBrowser/#/R-CEL-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Caenorhabditis elegans 37565 R-CEL-9653108 https://reactome.org/PathwayBrowser/#/R-CEL-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Caenorhabditis elegans 37565 R-CEL-9654523 https://reactome.org/PathwayBrowser/#/R-CEL-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Caenorhabditis elegans 37565 R-CEL-9654533 https://reactome.org/PathwayBrowser/#/R-CEL-9654533 KRAS4B recycles to the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9657599 https://reactome.org/PathwayBrowser/#/R-CEL-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Caenorhabditis elegans 37565 R-CEL-9657603 https://reactome.org/PathwayBrowser/#/R-CEL-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Caenorhabditis elegans 37565 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 37565 R-CEL-9657608 https://reactome.org/PathwayBrowser/#/R-CEL-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Caenorhabditis elegans 37565 R-CEL-9658253 https://reactome.org/PathwayBrowser/#/R-CEL-9658253 RAS:GTP binds PI3K IEA Caenorhabditis elegans 37565 R-CEL-9658445 https://reactome.org/PathwayBrowser/#/R-CEL-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Caenorhabditis elegans 37565 R-CEL-9660557 https://reactome.org/PathwayBrowser/#/R-CEL-9660557 RAS:GTP binds RAL GDS proteins IEA Caenorhabditis elegans 37565 R-CEL-9690493 https://reactome.org/PathwayBrowser/#/R-CEL-9690493 RHOB binds effectors on endosomes IEA Caenorhabditis elegans 37565 R-CEL-9690494 https://reactome.org/PathwayBrowser/#/R-CEL-9690494 RHOB translocates to the endosome membrane IEA Caenorhabditis elegans 37565 R-CEL-9691168 https://reactome.org/PathwayBrowser/#/R-CEL-9691168 RAC1 translocates to the endoplasmic reticulum membrane IEA Caenorhabditis elegans 37565 R-CEL-9692800 https://reactome.org/PathwayBrowser/#/R-CEL-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Caenorhabditis elegans 37565 R-CEL-9693111 https://reactome.org/PathwayBrowser/#/R-CEL-9693111 RHOF auto-activates IEA Caenorhabditis elegans 37565 R-CEL-9693125 https://reactome.org/PathwayBrowser/#/R-CEL-9693125 RHOF binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9693198 https://reactome.org/PathwayBrowser/#/R-CEL-9693198 RHOD binds effectors at the plasma membrane IEA Caenorhabditis elegans 37565 R-CEL-9693207 https://reactome.org/PathwayBrowser/#/R-CEL-9693207 RHOD translocates to the mitochondrial outer membrane IEA Caenorhabditis elegans 37565 R-CEL-9693214 https://reactome.org/PathwayBrowser/#/R-CEL-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Caenorhabditis elegans 37565 R-CEL-9693243 https://reactome.org/PathwayBrowser/#/R-CEL-9693243 RHOD translocates to the Golgi membrane IEA Caenorhabditis elegans 37565 R-CEL-9693250 https://reactome.org/PathwayBrowser/#/R-CEL-9693250 RHOD binds effectors at the Golgi membrane IEA Caenorhabditis elegans 37565 R-CEL-9693282 https://reactome.org/PathwayBrowser/#/R-CEL-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Caenorhabditis elegans 37565 R-CEL-9714477 https://reactome.org/PathwayBrowser/#/R-CEL-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Caenorhabditis elegans 37565 R-CEL-9714480 https://reactome.org/PathwayBrowser/#/R-CEL-9714480 RAC2 translocates to the mitochondrial membrane IEA Caenorhabditis elegans 37565 R-CEL-9714483 https://reactome.org/PathwayBrowser/#/R-CEL-9714483 RAC2 translocates to the ER membrane IEA Caenorhabditis elegans 37565 R-CEL-9714694 https://reactome.org/PathwayBrowser/#/R-CEL-9714694 RAC3 translocates to the endoplasmic reticulum membrane IEA Caenorhabditis elegans 37565 R-CEL-983259 https://reactome.org/PathwayBrowser/#/R-CEL-983259 Kinesins move along microtubules consuming ATP IEA Caenorhabditis elegans 37565 R-CFA-1008248 https://reactome.org/PathwayBrowser/#/R-CFA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Canis familiaris 37565 R-CFA-111524 https://reactome.org/PathwayBrowser/#/R-CFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Canis familiaris 37565 R-CFA-111879 https://reactome.org/PathwayBrowser/#/R-CFA-111879 PIP2 hydrolysis IEA Canis familiaris 37565 R-CFA-112037 https://reactome.org/PathwayBrowser/#/R-CFA-112037 Inactivation of PLC beta IEA Canis familiaris 37565 R-CFA-112271 https://reactome.org/PathwayBrowser/#/R-CFA-112271 The receptor:G-protein complex dissociates IEA Canis familiaris 37565 R-CFA-114542 https://reactome.org/PathwayBrowser/#/R-CFA-114542 RAC1,RAC2,RHOG activate PI3K IEA Canis familiaris 37565 R-CFA-114544 https://reactome.org/PathwayBrowser/#/R-CFA-114544 p115-RhoGEF activation of RHOA IEA Canis familiaris 37565 R-CFA-114548 https://reactome.org/PathwayBrowser/#/R-CFA-114548 G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) IEA Canis familiaris 37565 R-CFA-114552 https://reactome.org/PathwayBrowser/#/R-CFA-114552 Thrombin-activated PARs activate G12/13 IEA Canis familiaris 37565 R-CFA-114558 https://reactome.org/PathwayBrowser/#/R-CFA-114558 Thrombin-activated PARs activate Gq IEA Canis familiaris 37565 R-CFA-114688 https://reactome.org/PathwayBrowser/#/R-CFA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Canis familiaris 37565 R-CFA-1168636 https://reactome.org/PathwayBrowser/#/R-CFA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Canis familiaris 37565 R-CFA-1250383 https://reactome.org/PathwayBrowser/#/R-CFA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Canis familiaris 37565 R-CFA-1306972 https://reactome.org/PathwayBrowser/#/R-CFA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Canis familiaris 37565 R-CFA-1433415 https://reactome.org/PathwayBrowser/#/R-CFA-1433415 Activation of RAC1 IEA Canis familiaris 37565 R-CFA-1433471 https://reactome.org/PathwayBrowser/#/R-CFA-1433471 Activation of RAS by p-KIT bound SOS1 IEA Canis familiaris 37565 R-CFA-1474146 https://reactome.org/PathwayBrowser/#/R-CFA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Canis familiaris 37565 R-CFA-156808 https://reactome.org/PathwayBrowser/#/R-CFA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Canis familiaris 37565 R-CFA-156823 https://reactome.org/PathwayBrowser/#/R-CFA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Canis familiaris 37565 R-CFA-156913 https://reactome.org/PathwayBrowser/#/R-CFA-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Canis familiaris 37565 R-CFA-156930 https://reactome.org/PathwayBrowser/#/R-CFA-156930 GTP-binding activates eEF2 IEA Canis familiaris 37565 R-CFA-157849 https://reactome.org/PathwayBrowser/#/R-CFA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Canis familiaris 37565 R-CFA-1638803 https://reactome.org/PathwayBrowser/#/R-CFA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Canis familiaris 37565 R-CFA-1638821 https://reactome.org/PathwayBrowser/#/R-CFA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Canis familiaris 37565 R-CFA-165195 https://reactome.org/PathwayBrowser/#/R-CFA-165195 GTP loading by Rheb IEA Canis familiaris 37565 R-CFA-165680 https://reactome.org/PathwayBrowser/#/R-CFA-165680 Formation of active mTORC1 complex IEA Canis familiaris 37565 R-CFA-165692 https://reactome.org/PathwayBrowser/#/R-CFA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Canis familiaris 37565 R-CFA-165718 https://reactome.org/PathwayBrowser/#/R-CFA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Canis familiaris 37565 R-CFA-167415 https://reactome.org/PathwayBrowser/#/R-CFA-167415 G-protein alpha subunit is inactivated IEA Canis familiaris 37565 R-CFA-167429 https://reactome.org/PathwayBrowser/#/R-CFA-167429 The receptor:G-protein complex binds GTP IEA Canis familiaris 37565 R-CFA-169904 https://reactome.org/PathwayBrowser/#/R-CFA-169904 C3G stimulates nucleotide exchange on Rap1 IEA Canis familiaris 37565 R-CFA-170026 https://reactome.org/PathwayBrowser/#/R-CFA-170026 Protons are translocated from the intermembrane space to the matrix IEA Canis familiaris 37565 R-CFA-170666 https://reactome.org/PathwayBrowser/#/R-CFA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Canis familiaris 37565 R-CFA-170671 https://reactome.org/PathwayBrowser/#/R-CFA-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Canis familiaris 37565 R-CFA-170672 https://reactome.org/PathwayBrowser/#/R-CFA-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Canis familiaris 37565 R-CFA-170676 https://reactome.org/PathwayBrowser/#/R-CFA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Canis familiaris 37565 R-CFA-170685 https://reactome.org/PathwayBrowser/#/R-CFA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Canis familiaris 37565 R-CFA-170686 https://reactome.org/PathwayBrowser/#/R-CFA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Canis familiaris 37565 R-CFA-170986 https://reactome.org/PathwayBrowser/#/R-CFA-170986 Ral-GDS binds to Ras-GTP IEA Canis familiaris 37565 R-CFA-177938 https://reactome.org/PathwayBrowser/#/R-CFA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Canis familiaris 37565 R-CFA-177945 https://reactome.org/PathwayBrowser/#/R-CFA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Canis familiaris 37565 R-CFA-183002 https://reactome.org/PathwayBrowser/#/R-CFA-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Canis familiaris 37565 R-CFA-183084 https://reactome.org/PathwayBrowser/#/R-CFA-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Canis familiaris 37565 R-CFA-183094 https://reactome.org/PathwayBrowser/#/R-CFA-183094 CDC42:GTP binds CBL:Beta-Pix IEA Canis familiaris 37565 R-CFA-186834 https://reactome.org/PathwayBrowser/#/R-CFA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Canis familiaris 37565 R-CFA-190520 https://reactome.org/PathwayBrowser/#/R-CFA-190520 Association of Golgi transport vesicles with microtubules IEA Canis familiaris 37565 R-CFA-194518 https://reactome.org/PathwayBrowser/#/R-CFA-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Canis familiaris 37565 R-CFA-2029451 https://reactome.org/PathwayBrowser/#/R-CFA-2029451 Activation of RAC1 by VAV IEA Canis familiaris 37565 R-CFA-2029454 https://reactome.org/PathwayBrowser/#/R-CFA-2029454 Autophosphorylation of PAK1 IEA Canis familiaris 37565 R-CFA-2029456 https://reactome.org/PathwayBrowser/#/R-CFA-2029456 RAC1 and CDC42 activate PAK1 IEA Canis familiaris 37565 R-CFA-2029465 https://reactome.org/PathwayBrowser/#/R-CFA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Canis familiaris 37565 R-CFA-2029466 https://reactome.org/PathwayBrowser/#/R-CFA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Canis familiaris 37565 R-CFA-2029467 https://reactome.org/PathwayBrowser/#/R-CFA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Canis familiaris 37565 R-CFA-2029469 https://reactome.org/PathwayBrowser/#/R-CFA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Canis familiaris 37565 R-CFA-203973 https://reactome.org/PathwayBrowser/#/R-CFA-203973 Vesicle budding IEA Canis familiaris 37565 R-CFA-203977 https://reactome.org/PathwayBrowser/#/R-CFA-203977 SAR1 Activation And Membrane Binding IEA Canis familiaris 37565 R-CFA-203979 https://reactome.org/PathwayBrowser/#/R-CFA-203979 Coat Assembly IEA Canis familiaris 37565 R-CFA-204008 https://reactome.org/PathwayBrowser/#/R-CFA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Canis familiaris 37565 R-CFA-205039 https://reactome.org/PathwayBrowser/#/R-CFA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Canis familiaris 37565 R-CFA-205136 https://reactome.org/PathwayBrowser/#/R-CFA-205136 GTP-bound RAC contributes to JNK activation IEA Canis familiaris 37565 R-CFA-2065539 https://reactome.org/PathwayBrowser/#/R-CFA-2065539 SREBP1A,1C,2:Importin beta-1 dissociates IEA Canis familiaris 37565 R-CFA-210977 https://reactome.org/PathwayBrowser/#/R-CFA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Canis familiaris 37565 R-CFA-2130194 https://reactome.org/PathwayBrowser/#/R-CFA-2130194 ABL phosphorylates WAVEs IEA Canis familiaris 37565 R-CFA-2130619 https://reactome.org/PathwayBrowser/#/R-CFA-2130619 TGN-lysosomal vesicle coat assembly IEA Canis familiaris 37565 R-CFA-2130641 https://reactome.org/PathwayBrowser/#/R-CFA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Canis familiaris 37565 R-CFA-2130725 https://reactome.org/PathwayBrowser/#/R-CFA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Canis familiaris 37565 R-CFA-2130731 https://reactome.org/PathwayBrowser/#/R-CFA-2130731 Formation of COPII vesicle IEA Canis familiaris 37565 R-CFA-2179407 https://reactome.org/PathwayBrowser/#/R-CFA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Canis familiaris 37565 R-CFA-2197690 https://reactome.org/PathwayBrowser/#/R-CFA-2197690 Detachment of WASP/WAVE IEA Canis familiaris 37565 R-CFA-2197691 https://reactome.org/PathwayBrowser/#/R-CFA-2197691 WIP binds WASP,N-WASP, activating them IEA Canis familiaris 37565 R-CFA-2197698 https://reactome.org/PathwayBrowser/#/R-CFA-2197698 Src phosphorylate WASP,N-WASP IEA Canis familiaris 37565 R-CFA-2213243 https://reactome.org/PathwayBrowser/#/R-CFA-2213243 Fusion of COPII vesicle with Golgi complex IEA Canis familiaris 37565 R-CFA-2213248 https://reactome.org/PathwayBrowser/#/R-CFA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Canis familiaris 37565 R-CFA-2214351 https://reactome.org/PathwayBrowser/#/R-CFA-2214351 PLK1 phosphorylates GORASP1 IEA Canis familiaris 37565 R-CFA-2316434 https://reactome.org/PathwayBrowser/#/R-CFA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 37565 R-CFA-2422927 https://reactome.org/PathwayBrowser/#/R-CFA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Canis familiaris 37565 R-CFA-2424476 https://reactome.org/PathwayBrowser/#/R-CFA-2424476 Activation of RAC1 by VAV2/3 IEA Canis familiaris 37565 R-CFA-2424477 https://reactome.org/PathwayBrowser/#/R-CFA-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Canis familiaris 37565 R-CFA-2467809 https://reactome.org/PathwayBrowser/#/R-CFA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Canis familiaris 37565 R-CFA-2467811 https://reactome.org/PathwayBrowser/#/R-CFA-2467811 Separation of sister chromatids IEA Canis familiaris 37565 R-CFA-2468287 https://reactome.org/PathwayBrowser/#/R-CFA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Canis familiaris 37565 R-CFA-2484822 https://reactome.org/PathwayBrowser/#/R-CFA-2484822 Kinetochore assembly IEA Canis familiaris 37565 R-CFA-2485182 https://reactome.org/PathwayBrowser/#/R-CFA-2485182 Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 IEA Canis familiaris 37565 R-CFA-2562526 https://reactome.org/PathwayBrowser/#/R-CFA-2562526 PLK1 phosphorylates OPTN IEA Canis familiaris 37565 R-CFA-2584246 https://reactome.org/PathwayBrowser/#/R-CFA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Canis familiaris 37565 R-CFA-2730840 https://reactome.org/PathwayBrowser/#/R-CFA-2730840 Activation of RAC1 by VAV IEA Canis familiaris 37565 R-CFA-2730856 https://reactome.org/PathwayBrowser/#/R-CFA-2730856 Autophosphorylation of PAK IEA Canis familiaris 37565 R-CFA-2730889 https://reactome.org/PathwayBrowser/#/R-CFA-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Canis familiaris 37565 R-CFA-350769 https://reactome.org/PathwayBrowser/#/R-CFA-350769 trans-Golgi Network Coat Activation IEA Canis familiaris 37565 R-CFA-354060 https://reactome.org/PathwayBrowser/#/R-CFA-354060 Translocation of RIAM to plasma membrane IEA Canis familiaris 37565 R-CFA-354066 https://reactome.org/PathwayBrowser/#/R-CFA-354066 Translocation of PTK2 to Focal complexes IEA Canis familiaris 37565 R-CFA-354073 https://reactome.org/PathwayBrowser/#/R-CFA-354073 Autophosphorylation of PTK2 at Y397 IEA Canis familiaris 37565 R-CFA-354077 https://reactome.org/PathwayBrowser/#/R-CFA-354077 Integrin alphaIIb beta3 activation IEA Canis familiaris 37565 R-CFA-354087 https://reactome.org/PathwayBrowser/#/R-CFA-354087 Recruitment of GRB2 to p-PTK2 IEA Canis familiaris 37565 R-CFA-354097 https://reactome.org/PathwayBrowser/#/R-CFA-354097 Activation of Talin IEA Canis familiaris 37565 R-CFA-354124 https://reactome.org/PathwayBrowser/#/R-CFA-354124 Phosphorylation of pPTK2 by SRC IEA Canis familiaris 37565 R-CFA-354149 https://reactome.org/PathwayBrowser/#/R-CFA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Canis familiaris 37565 R-CFA-354165 https://reactome.org/PathwayBrowser/#/R-CFA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Canis familiaris 37565 R-CFA-354173 https://reactome.org/PathwayBrowser/#/R-CFA-354173 Activation of Rap1 by cytosolic GEFs IEA Canis familiaris 37565 R-CFA-372693 https://reactome.org/PathwayBrowser/#/R-CFA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Canis familiaris 37565 R-CFA-372697 https://reactome.org/PathwayBrowser/#/R-CFA-372697 Crk binding to p130cas IEA Canis familiaris 37565 R-CFA-372705 https://reactome.org/PathwayBrowser/#/R-CFA-372705 Recruitment of BCAR1 to PTK2 complex IEA Canis familiaris 37565 R-CFA-372819 https://reactome.org/PathwayBrowser/#/R-CFA-372819 PCK2 phosphorylates OA to yield PEP IEA Canis familiaris 37565 R-CFA-375302 https://reactome.org/PathwayBrowser/#/R-CFA-375302 Kinetochore capture of astral microtubules IEA Canis familiaris 37565 R-CFA-377640 https://reactome.org/PathwayBrowser/#/R-CFA-377640 Autophosphorylation of SRC IEA Canis familiaris 37565 R-CFA-377641 https://reactome.org/PathwayBrowser/#/R-CFA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Canis familiaris 37565 R-CFA-377643 https://reactome.org/PathwayBrowser/#/R-CFA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Canis familiaris 37565 R-CFA-377644 https://reactome.org/PathwayBrowser/#/R-CFA-377644 Release of CSK from SRC IEA Canis familiaris 37565 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 37565 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 37565 R-CFA-380316 https://reactome.org/PathwayBrowser/#/R-CFA-380316 Association of NuMA with microtubules IEA Canis familiaris 37565 R-CFA-380979 https://reactome.org/PathwayBrowser/#/R-CFA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Canis familiaris 37565 R-CFA-381727 https://reactome.org/PathwayBrowser/#/R-CFA-381727 RAP1A exchanges GDP for GTP IEA Canis familiaris 37565 R-CFA-3858475 https://reactome.org/PathwayBrowser/#/R-CFA-3858475 ppDVL recruits RAC IEA Canis familiaris 37565 R-CFA-3858495 https://reactome.org/PathwayBrowser/#/R-CFA-3858495 DAAM1 recruits GTP-bound RHOA IEA Canis familiaris 37565 R-CFA-389348 https://reactome.org/PathwayBrowser/#/R-CFA-389348 Activation of Rac1 by pVav1 IEA Canis familiaris 37565 R-CFA-389350 https://reactome.org/PathwayBrowser/#/R-CFA-389350 Activation of Cdc42 by pVav1 IEA Canis familiaris 37565 R-CFA-389788 https://reactome.org/PathwayBrowser/#/R-CFA-389788 Activation of PAKs by RAC1 and CDC42 IEA Canis familiaris 37565 R-CFA-392054 https://reactome.org/PathwayBrowser/#/R-CFA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Canis familiaris 37565 R-CFA-392064 https://reactome.org/PathwayBrowser/#/R-CFA-392064 G alpha (z) inhibits adenylate cyclase IEA Canis familiaris 37565 R-CFA-392195 https://reactome.org/PathwayBrowser/#/R-CFA-392195 Gi activation by P2Y purinoceptor 12 IEA Canis familiaris 37565 R-CFA-392202 https://reactome.org/PathwayBrowser/#/R-CFA-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Canis familiaris 37565 R-CFA-392513 https://reactome.org/PathwayBrowser/#/R-CFA-392513 Rap1 signal termination by Rap1GAPs IEA Canis familiaris 37565 R-CFA-392835 https://reactome.org/PathwayBrowser/#/R-CFA-392835 Rap1 sequesters Raf1 to inhibit ERK cascade IEA Canis familiaris 37565 R-CFA-3928576 https://reactome.org/PathwayBrowser/#/R-CFA-3928576 RHOA:GTP binds ROCK, activating it IEA Canis familiaris 37565 R-CFA-3928592 https://reactome.org/PathwayBrowser/#/R-CFA-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Canis familiaris 37565 R-CFA-3928595 https://reactome.org/PathwayBrowser/#/R-CFA-3928595 N-WASP binds ARP2/3 and G-actin IEA Canis familiaris 37565 R-CFA-3928601 https://reactome.org/PathwayBrowser/#/R-CFA-3928601 CDC42 and PIP2 bind WASL, activating it IEA Canis familiaris 37565 R-CFA-3928612 https://reactome.org/PathwayBrowser/#/R-CFA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 37565 R-CFA-3928619 https://reactome.org/PathwayBrowser/#/R-CFA-3928619 PAK1 binds RAC1:GTP IEA Canis familiaris 37565 R-CFA-3928620 https://reactome.org/PathwayBrowser/#/R-CFA-3928620 PAK1 autophosphorylates IEA Canis familiaris 37565 R-CFA-3928625 https://reactome.org/PathwayBrowser/#/R-CFA-3928625 PAKs autophosphorylate IEA Canis familiaris 37565 R-CFA-3928628 https://reactome.org/PathwayBrowser/#/R-CFA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 37565 R-CFA-3928633 https://reactome.org/PathwayBrowser/#/R-CFA-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Canis familiaris 37565 R-CFA-3928640 https://reactome.org/PathwayBrowser/#/R-CFA-3928640 PAKs phosphorylate MLC IEA Canis familiaris 37565 R-CFA-3928641 https://reactome.org/PathwayBrowser/#/R-CFA-3928641 PAK binds RAC and bPIX IEA Canis familiaris 37565 R-CFA-3928642 https://reactome.org/PathwayBrowser/#/R-CFA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 37565 R-CFA-3928647 https://reactome.org/PathwayBrowser/#/R-CFA-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Canis familiaris 37565 R-CFA-3928651 https://reactome.org/PathwayBrowser/#/R-CFA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Canis familiaris 37565 R-CFA-392870 https://reactome.org/PathwayBrowser/#/R-CFA-392870 Gs activation by prostacyclin receptor IEA Canis familiaris 37565 R-CFA-3965444 https://reactome.org/PathwayBrowser/#/R-CFA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Canis familiaris 37565 R-CFA-3965447 https://reactome.org/PathwayBrowser/#/R-CFA-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Canis familiaris 37565 R-CFA-397835 https://reactome.org/PathwayBrowser/#/R-CFA-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Canis familiaris 37565 R-CFA-397891 https://reactome.org/PathwayBrowser/#/R-CFA-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Canis familiaris 37565 R-CFA-398184 https://reactome.org/PathwayBrowser/#/R-CFA-398184 LARG activation by G alpha 12/13 IEA Canis familiaris 37565 R-CFA-398185 https://reactome.org/PathwayBrowser/#/R-CFA-398185 LARG binds plexin B1 IEA Canis familiaris 37565 R-CFA-399930 https://reactome.org/PathwayBrowser/#/R-CFA-399930 Activation of PAK by Rac1 IEA Canis familiaris 37565 R-CFA-399939 https://reactome.org/PathwayBrowser/#/R-CFA-399939 Autophosphorylation of PAK IEA Canis familiaris 37565 R-CFA-399952 https://reactome.org/PathwayBrowser/#/R-CFA-399952 Phosphorylation of LIMK-1 by PAK IEA Canis familiaris 37565 R-CFA-399998 https://reactome.org/PathwayBrowser/#/R-CFA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Canis familiaris 37565 R-CFA-400037 https://reactome.org/PathwayBrowser/#/R-CFA-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Canis familiaris 37565 R-CFA-400092 https://reactome.org/PathwayBrowser/#/R-CFA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Canis familiaris 37565 R-CFA-400586 https://reactome.org/PathwayBrowser/#/R-CFA-400586 G alpha (q) binds to Trio family RhoGEFs IEA Canis familiaris 37565 R-CFA-400677 https://reactome.org/PathwayBrowser/#/R-CFA-400677 Rnd1 interacts with Plexin-B1:Sema4D IEA Canis familiaris 37565 R-CFA-400682 https://reactome.org/PathwayBrowser/#/R-CFA-400682 Active Rac1 interacts with Plexin-B1:Sema4D IEA Canis familiaris 37565 R-CFA-4086392 https://reactome.org/PathwayBrowser/#/R-CFA-4086392 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 37565 R-CFA-4093331 https://reactome.org/PathwayBrowser/#/R-CFA-4093331 Ras:GTP binds p120-RasGAP IEA Canis familiaris 37565 R-CFA-4093336 https://reactome.org/PathwayBrowser/#/R-CFA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 37565 R-CFA-4093339 https://reactome.org/PathwayBrowser/#/R-CFA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Canis familiaris 37565 R-CFA-416358 https://reactome.org/PathwayBrowser/#/R-CFA-416358 G alpha (q) inhibits PI3K alpha IEA Canis familiaris 37565 R-CFA-416516 https://reactome.org/PathwayBrowser/#/R-CFA-416516 GRK2 sequesters activated Gq IEA Canis familiaris 37565 R-CFA-416530 https://reactome.org/PathwayBrowser/#/R-CFA-416530 FFAR1:FFAR1 ligands activate Gq IEA Canis familiaris 37565 R-CFA-416546 https://reactome.org/PathwayBrowser/#/R-CFA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Canis familiaris 37565 R-CFA-416559 https://reactome.org/PathwayBrowser/#/R-CFA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Canis familiaris 37565 R-CFA-416562 https://reactome.org/PathwayBrowser/#/R-CFA-416562 p190RhoGAP binds Plexin-B1 IEA Canis familiaris 37565 R-CFA-416588 https://reactome.org/PathwayBrowser/#/R-CFA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Canis familiaris 37565 R-CFA-418574 https://reactome.org/PathwayBrowser/#/R-CFA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Canis familiaris 37565 R-CFA-418576 https://reactome.org/PathwayBrowser/#/R-CFA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Canis familiaris 37565 R-CFA-418582 https://reactome.org/PathwayBrowser/#/R-CFA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Canis familiaris 37565 R-CFA-418850 https://reactome.org/PathwayBrowser/#/R-CFA-418850 Activation of Cdc42 IEA Canis familiaris 37565 R-CFA-418856 https://reactome.org/PathwayBrowser/#/R-CFA-418856 Activation of Rac1 IEA Canis familiaris 37565 R-CFA-418874 https://reactome.org/PathwayBrowser/#/R-CFA-418874 Recruitment and activation of N-WASP by Cdc42 IEA Canis familiaris 37565 R-CFA-419049 https://reactome.org/PathwayBrowser/#/R-CFA-419049 ROCK activation by RHO IEA Canis familiaris 37565 R-CFA-419166 https://reactome.org/PathwayBrowser/#/R-CFA-419166 GEFs activate RhoA,B,C IEA Canis familiaris 37565 R-CFA-420883 https://reactome.org/PathwayBrowser/#/R-CFA-420883 Opsins act as GEFs for G alpha-t IEA Canis familiaris 37565 R-CFA-421831 https://reactome.org/PathwayBrowser/#/R-CFA-421831 trans-Golgi Network Coat Assembly IEA Canis familiaris 37565 R-CFA-421833 https://reactome.org/PathwayBrowser/#/R-CFA-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture IEA Canis familiaris 37565 R-CFA-421835 https://reactome.org/PathwayBrowser/#/R-CFA-421835 trans-Golgi Network Vesicle Scission IEA Canis familiaris 37565 R-CFA-428750 https://reactome.org/PathwayBrowser/#/R-CFA-428750 Gq activation by TP receptor IEA Canis familiaris 37565 R-CFA-428752 https://reactome.org/PathwayBrowser/#/R-CFA-428752 Dissociation of the TP:Gq complex IEA Canis familiaris 37565 R-CFA-428917 https://reactome.org/PathwayBrowser/#/R-CFA-428917 G13 activation by TP receptor IEA Canis familiaris 37565 R-CFA-428918 https://reactome.org/PathwayBrowser/#/R-CFA-428918 Dissociation of the TP:G13 complex IEA Canis familiaris 37565 R-CFA-428941 https://reactome.org/PathwayBrowser/#/R-CFA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Canis familiaris 37565 R-CFA-429415 https://reactome.org/PathwayBrowser/#/R-CFA-429415 SYK binds to integrin alphaIIb beta3 IEA Canis familiaris 37565 R-CFA-429441 https://reactome.org/PathwayBrowser/#/R-CFA-429441 SYK activation by SRC IEA Canis familiaris 37565 R-CFA-432096 https://reactome.org/PathwayBrowser/#/R-CFA-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Canis familiaris 37565 R-CFA-432195 https://reactome.org/PathwayBrowser/#/R-CFA-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Canis familiaris 37565 R-CFA-432706 https://reactome.org/PathwayBrowser/#/R-CFA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Canis familiaris 37565 R-CFA-432707 https://reactome.org/PathwayBrowser/#/R-CFA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Canis familiaris 37565 R-CFA-432712 https://reactome.org/PathwayBrowser/#/R-CFA-432712 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane IEA Canis familiaris 37565 R-CFA-442273 https://reactome.org/PathwayBrowser/#/R-CFA-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Canis familiaris 37565 R-CFA-442291 https://reactome.org/PathwayBrowser/#/R-CFA-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Canis familiaris 37565 R-CFA-442314 https://reactome.org/PathwayBrowser/#/R-CFA-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Canis familiaris 37565 R-CFA-443905 https://reactome.org/PathwayBrowser/#/R-CFA-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Canis familiaris 37565 R-CFA-443910 https://reactome.org/PathwayBrowser/#/R-CFA-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Canis familiaris 37565 R-CFA-445064 https://reactome.org/PathwayBrowser/#/R-CFA-445064 Activation of Rac1 by VAV2 IEA Canis familiaris 37565 R-CFA-445072 https://reactome.org/PathwayBrowser/#/R-CFA-445072 Interaction of PAK1 with Rac1-GTP IEA Canis familiaris 37565 R-CFA-447074 https://reactome.org/PathwayBrowser/#/R-CFA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Canis familiaris 37565 R-CFA-448958 https://reactome.org/PathwayBrowser/#/R-CFA-448958 Nuclear translocation of p38 MAPK IEA Canis familiaris 37565 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 37565 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 37565 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 37565 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 37565 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 37565 R-CFA-5218804 https://reactome.org/PathwayBrowser/#/R-CFA-5218804 p38 MAPK activation by VEGFR IEA Canis familiaris 37565 R-CFA-5218812 https://reactome.org/PathwayBrowser/#/R-CFA-5218812 FYN phosphorylates PAK2 IEA Canis familiaris 37565 R-CFA-5218814 https://reactome.org/PathwayBrowser/#/R-CFA-5218814 PAK2 autophorylates IEA Canis familiaris 37565 R-CFA-5218826 https://reactome.org/PathwayBrowser/#/R-CFA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Canis familiaris 37565 R-CFA-5218827 https://reactome.org/PathwayBrowser/#/R-CFA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Canis familiaris 37565 R-CFA-5218832 https://reactome.org/PathwayBrowser/#/R-CFA-5218832 CDC42:GTP binds PAK2 IEA Canis familiaris 37565 R-CFA-5218839 https://reactome.org/PathwayBrowser/#/R-CFA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Canis familiaris 37565 R-CFA-5218841 https://reactome.org/PathwayBrowser/#/R-CFA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Canis familiaris 37565 R-CFA-5218845 https://reactome.org/PathwayBrowser/#/R-CFA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Canis familiaris 37565 R-CFA-5218850 https://reactome.org/PathwayBrowser/#/R-CFA-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 37565 R-CFA-5228992 https://reactome.org/PathwayBrowser/#/R-CFA-5228992 ROCK1,ROCK2 are activated IEA Canis familiaris 37565 R-CFA-5250209 https://reactome.org/PathwayBrowser/#/R-CFA-5250209 ARL2:GTP:ARL2BP binds SLC25A4 IEA Canis familiaris 37565 R-CFA-5250210 https://reactome.org/PathwayBrowser/#/R-CFA-5250210 ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix IEA Canis familiaris 37565 R-CFA-5250217 https://reactome.org/PathwayBrowser/#/R-CFA-5250217 ARL2:GTP binds ARL2BP IEA Canis familiaris 37565 R-CFA-5357445 https://reactome.org/PathwayBrowser/#/R-CFA-5357445 PAK1-3 dimer disassociates IEA Canis familiaris 37565 R-CFA-5357472 https://reactome.org/PathwayBrowser/#/R-CFA-5357472 PAK1-3 autophosphorylates IEA Canis familiaris 37565 R-CFA-5357483 https://reactome.org/PathwayBrowser/#/R-CFA-5357483 RAC1 binds PAK1-3 IEA Canis familiaris 37565 R-CFA-5419261 https://reactome.org/PathwayBrowser/#/R-CFA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Canis familiaris 37565 R-CFA-5419264 https://reactome.org/PathwayBrowser/#/R-CFA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Canis familiaris 37565 R-CFA-5419271 https://reactome.org/PathwayBrowser/#/R-CFA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Canis familiaris 37565 R-CFA-5419273 https://reactome.org/PathwayBrowser/#/R-CFA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Canis familiaris 37565 R-CFA-555065 https://reactome.org/PathwayBrowser/#/R-CFA-555065 Formation of clathrin coated vesicle IEA Canis familiaris 37565 R-CFA-5578744 https://reactome.org/PathwayBrowser/#/R-CFA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Canis familiaris 37565 R-CFA-5610733 https://reactome.org/PathwayBrowser/#/R-CFA-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Canis familiaris 37565 R-CFA-5610767 https://reactome.org/PathwayBrowser/#/R-CFA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Canis familiaris 37565 R-CFA-5617816 https://reactome.org/PathwayBrowser/#/R-CFA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Canis familiaris 37565 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 37565 R-CFA-5618328 https://reactome.org/PathwayBrowser/#/R-CFA-5618328 ATAT acetylates microtubules IEA Canis familiaris 37565 R-CFA-5618331 https://reactome.org/PathwayBrowser/#/R-CFA-5618331 HDAC6 deacetylates microtubules IEA Canis familiaris 37565 R-CFA-5620914 https://reactome.org/PathwayBrowser/#/R-CFA-5620914 ARF4:GTP binds VxPx-motifs of membrane proteins IEA Canis familiaris 37565 R-CFA-5620921 https://reactome.org/PathwayBrowser/#/R-CFA-5620921 ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex IEA Canis familiaris 37565 R-CFA-5623508 https://reactome.org/PathwayBrowser/#/R-CFA-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Canis familiaris 37565 R-CFA-5623513 https://reactome.org/PathwayBrowser/#/R-CFA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Canis familiaris 37565 R-CFA-5623519 https://reactome.org/PathwayBrowser/#/R-CFA-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Canis familiaris 37565 R-CFA-5623521 https://reactome.org/PathwayBrowser/#/R-CFA-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Canis familiaris 37565 R-CFA-5623524 https://reactome.org/PathwayBrowser/#/R-CFA-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Canis familiaris 37565 R-CFA-5623525 https://reactome.org/PathwayBrowser/#/R-CFA-5623525 Cargo-carrying vesicles bud from the TGN IEA Canis familiaris 37565 R-CFA-5623527 https://reactome.org/PathwayBrowser/#/R-CFA-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Canis familiaris 37565 R-CFA-5623622 https://reactome.org/PathwayBrowser/#/R-CFA-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Canis familiaris 37565 R-CFA-5623632 https://reactome.org/PathwayBrowser/#/R-CFA-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Canis familiaris 37565 R-CFA-5623667 https://reactome.org/PathwayBrowser/#/R-CFA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Canis familiaris 37565 R-CFA-5624126 https://reactome.org/PathwayBrowser/#/R-CFA-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Canis familiaris 37565 R-CFA-5624127 https://reactome.org/PathwayBrowser/#/R-CFA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Canis familiaris 37565 R-CFA-5624486 https://reactome.org/PathwayBrowser/#/R-CFA-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Canis familiaris 37565 R-CFA-5624492 https://reactome.org/PathwayBrowser/#/R-CFA-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Canis familiaris 37565 R-CFA-5624494 https://reactome.org/PathwayBrowser/#/R-CFA-5624494 RAF1 binds p21 RAS:GTP IEA Canis familiaris 37565 R-CFA-5625959 https://reactome.org/PathwayBrowser/#/R-CFA-5625959 Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) IEA Canis familiaris 37565 R-CFA-5626469 https://reactome.org/PathwayBrowser/#/R-CFA-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Canis familiaris 37565 R-CFA-5626507 https://reactome.org/PathwayBrowser/#/R-CFA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Canis familiaris 37565 R-CFA-5626549 https://reactome.org/PathwayBrowser/#/R-CFA-5626549 IQGAPs bind CALM1 IEA Canis familiaris 37565 R-CFA-5627071 https://reactome.org/PathwayBrowser/#/R-CFA-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane IEA Canis familiaris 37565 R-CFA-5627072 https://reactome.org/PathwayBrowser/#/R-CFA-5627072 RHOQ binds GOPC:CFTR IEA Canis familiaris 37565 R-CFA-5627775 https://reactome.org/PathwayBrowser/#/R-CFA-5627775 Autophosphorylation of PAK1,2,3 IEA Canis familiaris 37565 R-CFA-5638009 https://reactome.org/PathwayBrowser/#/R-CFA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Canis familiaris 37565 R-CFA-5638014 https://reactome.org/PathwayBrowser/#/R-CFA-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Canis familiaris 37565 R-CFA-5653957 https://reactome.org/PathwayBrowser/#/R-CFA-5653957 Rag dimer formation IEA Canis familiaris 37565 R-CFA-5653968 https://reactome.org/PathwayBrowser/#/R-CFA-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Canis familiaris 37565 R-CFA-5653974 https://reactome.org/PathwayBrowser/#/R-CFA-5653974 Ragulator binds Rag dimers IEA Canis familiaris 37565 R-CFA-5654392 https://reactome.org/PathwayBrowser/#/R-CFA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-5654402 https://reactome.org/PathwayBrowser/#/R-CFA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-5654413 https://reactome.org/PathwayBrowser/#/R-CFA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-5654426 https://reactome.org/PathwayBrowser/#/R-CFA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-5654600 https://reactome.org/PathwayBrowser/#/R-CFA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-5654618 https://reactome.org/PathwayBrowser/#/R-CFA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-5654647 https://reactome.org/PathwayBrowser/#/R-CFA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-5654663 https://reactome.org/PathwayBrowser/#/R-CFA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-5658231 https://reactome.org/PathwayBrowser/#/R-CFA-5658231 RAS GAPs stimulate RAS GTPase activity IEA Canis familiaris 37565 R-CFA-5658435 https://reactome.org/PathwayBrowser/#/R-CFA-5658435 RAS GAPs bind RAS:GTP IEA Canis familiaris 37565 R-CFA-5665727 https://reactome.org/PathwayBrowser/#/R-CFA-5665727 FMNL2 binds CDC42:GTP IEA Canis familiaris 37565 R-CFA-5665748 https://reactome.org/PathwayBrowser/#/R-CFA-5665748 FMNL2 binds RHOC:GTP IEA Canis familiaris 37565 R-CFA-5665751 https://reactome.org/PathwayBrowser/#/R-CFA-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin IEA Canis familiaris 37565 R-CFA-5665761 https://reactome.org/PathwayBrowser/#/R-CFA-5665761 FMNL3 binds RHOC:GTP IEA Canis familiaris 37565 R-CFA-5665767 https://reactome.org/PathwayBrowser/#/R-CFA-5665767 Activated FMNL3 binds G-actin IEA Canis familiaris 37565 R-CFA-5665802 https://reactome.org/PathwayBrowser/#/R-CFA-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Canis familiaris 37565 R-CFA-5665809 https://reactome.org/PathwayBrowser/#/R-CFA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Canis familiaris 37565 R-CFA-5665982 https://reactome.org/PathwayBrowser/#/R-CFA-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 IEA Canis familiaris 37565 R-CFA-5665989 https://reactome.org/PathwayBrowser/#/R-CFA-5665989 DIAPH1 binds RHOA:GTP IEA Canis familiaris 37565 R-CFA-5666070 https://reactome.org/PathwayBrowser/#/R-CFA-5666070 RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes IEA Canis familiaris 37565 R-CFA-5666088 https://reactome.org/PathwayBrowser/#/R-CFA-5666088 RHOD:GTP recruits DAIPH2-3 to endosomes IEA Canis familiaris 37565 R-CFA-5666104 https://reactome.org/PathwayBrowser/#/R-CFA-5666104 RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes IEA Canis familiaris 37565 R-CFA-5666129 https://reactome.org/PathwayBrowser/#/R-CFA-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Canis familiaris 37565 R-CFA-5666160 https://reactome.org/PathwayBrowser/#/R-CFA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Canis familiaris 37565 R-CFA-5666169 https://reactome.org/PathwayBrowser/#/R-CFA-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Canis familiaris 37565 R-CFA-5666197 https://reactome.org/PathwayBrowser/#/R-CFA-5666197 RHOA:GTP:RTKN binds LIN7B IEA Canis familiaris 37565 R-CFA-5666216 https://reactome.org/PathwayBrowser/#/R-CFA-5666216 RHOA:GTP:RTKN binds TAX1BP3 IEA Canis familiaris 37565 R-CFA-5667008 https://reactome.org/PathwayBrowser/#/R-CFA-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Canis familiaris 37565 R-CFA-5668605 https://reactome.org/PathwayBrowser/#/R-CFA-5668605 RAC2:GTP binds NOX2 complex IEA Canis familiaris 37565 R-CFA-5668629 https://reactome.org/PathwayBrowser/#/R-CFA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Canis familiaris 37565 R-CFA-5668714 https://reactome.org/PathwayBrowser/#/R-CFA-5668714 RAC1:GTP binds NOX1 complex IEA Canis familiaris 37565 R-CFA-5668718 https://reactome.org/PathwayBrowser/#/R-CFA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 37565 R-CFA-5668731 https://reactome.org/PathwayBrowser/#/R-CFA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 37565 R-CFA-5668735 https://reactome.org/PathwayBrowser/#/R-CFA-5668735 RAC1:GTP binds NOX3 complex IEA Canis familiaris 37565 R-CFA-5671970 https://reactome.org/PathwayBrowser/#/R-CFA-5671970 Activated CIT binds KIF14 and PRC1 IEA Canis familiaris 37565 R-CFA-5671993 https://reactome.org/PathwayBrowser/#/R-CFA-5671993 CIT-3 binds DLG4 IEA Canis familiaris 37565 R-CFA-5672010 https://reactome.org/PathwayBrowser/#/R-CFA-5672010 Active MTORC1 phosphorylates ULK1 IEA Canis familiaris 37565 R-CFA-5672017 https://reactome.org/PathwayBrowser/#/R-CFA-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Canis familiaris 37565 R-CFA-5672027 https://reactome.org/PathwayBrowser/#/R-CFA-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Canis familiaris 37565 R-CFA-5672083 https://reactome.org/PathwayBrowser/#/R-CFA-5672083 KTN1 binds Kinesin-1 IEA Canis familiaris 37565 R-CFA-5672817 https://reactome.org/PathwayBrowser/#/R-CFA-5672817 Active MTORC1 binds the ULK1 complex IEA Canis familiaris 37565 R-CFA-5672828 https://reactome.org/PathwayBrowser/#/R-CFA-5672828 mTORC1 phosphorylates AKT1S1 IEA Canis familiaris 37565 R-CFA-5672843 https://reactome.org/PathwayBrowser/#/R-CFA-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Canis familiaris 37565 R-CFA-5672965 https://reactome.org/PathwayBrowser/#/R-CFA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-5672969 https://reactome.org/PathwayBrowser/#/R-CFA-5672969 Phosphorylation of RAF IEA Canis familiaris 37565 R-CFA-5672972 https://reactome.org/PathwayBrowser/#/R-CFA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Canis familiaris 37565 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 37565 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 37565 R-CFA-5672980 https://reactome.org/PathwayBrowser/#/R-CFA-5672980 Dissociation of RAS:RAF complex IEA Canis familiaris 37565 R-CFA-5673768 https://reactome.org/PathwayBrowser/#/R-CFA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Canis familiaris 37565 R-CFA-5674018 https://reactome.org/PathwayBrowser/#/R-CFA-5674018 BRAP binds RAS:GTP IEA Canis familiaris 37565 R-CFA-5674022 https://reactome.org/PathwayBrowser/#/R-CFA-5674022 BRAP autoubiquitinates IEA Canis familiaris 37565 R-CFA-5675417 https://reactome.org/PathwayBrowser/#/R-CFA-5675417 PEBP1 binds activated RAF1 IEA Canis familiaris 37565 R-CFA-5675431 https://reactome.org/PathwayBrowser/#/R-CFA-5675431 PP2A dephosphorylates RAF1 IEA Canis familiaris 37565 R-CFA-5675433 https://reactome.org/PathwayBrowser/#/R-CFA-5675433 PP5 dephosphorylates RAF1 S338 IEA Canis familiaris 37565 R-CFA-5675790 https://reactome.org/PathwayBrowser/#/R-CFA-5675790 MTORC1 dissociates from ULK complex IEA Canis familiaris 37565 R-CFA-5694409 https://reactome.org/PathwayBrowser/#/R-CFA-5694409 Nucleotide exchange on RAB1 IEA Canis familiaris 37565 R-CFA-5694417 https://reactome.org/PathwayBrowser/#/R-CFA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Canis familiaris 37565 R-CFA-5694418 https://reactome.org/PathwayBrowser/#/R-CFA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Canis familiaris 37565 R-CFA-5694441 https://reactome.org/PathwayBrowser/#/R-CFA-5694441 CSNK1D phosphorylates SEC23 IEA Canis familiaris 37565 R-CFA-5694522 https://reactome.org/PathwayBrowser/#/R-CFA-5694522 Inner coat assembly and cargo binding IEA Canis familiaris 37565 R-CFA-5694527 https://reactome.org/PathwayBrowser/#/R-CFA-5694527 Loss of SAR1B GTPase IEA Canis familiaris 37565 R-CFA-5696197 https://reactome.org/PathwayBrowser/#/R-CFA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Canis familiaris 37565 R-CFA-6785648 https://reactome.org/PathwayBrowser/#/R-CFA-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Canis familiaris 37565 R-CFA-6787533 https://reactome.org/PathwayBrowser/#/R-CFA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Canis familiaris 37565 R-CFA-6788611 https://reactome.org/PathwayBrowser/#/R-CFA-6788611 HYKK phosphorylates 5HLYS IEA Canis familiaris 37565 R-CFA-6789092 https://reactome.org/PathwayBrowser/#/R-CFA-6789092 NOX2 generates superoxide anion from oxygen IEA Canis familiaris 37565 R-CFA-6800138 https://reactome.org/PathwayBrowser/#/R-CFA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Canis familiaris 37565 R-CFA-6807864 https://reactome.org/PathwayBrowser/#/R-CFA-6807864 RAB1:GTP recruits GBF1 to the ERGIC IEA Canis familiaris 37565 R-CFA-6807866 https://reactome.org/PathwayBrowser/#/R-CFA-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Canis familiaris 37565 R-CFA-6807868 https://reactome.org/PathwayBrowser/#/R-CFA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Canis familiaris 37565 R-CFA-6807872 https://reactome.org/PathwayBrowser/#/R-CFA-6807872 Active ARF recruits coatomer IEA Canis familiaris 37565 R-CFA-6807875 https://reactome.org/PathwayBrowser/#/R-CFA-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Canis familiaris 37565 R-CFA-6807877 https://reactome.org/PathwayBrowser/#/R-CFA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Canis familiaris 37565 R-CFA-6809003 https://reactome.org/PathwayBrowser/#/R-CFA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Canis familiaris 37565 R-CFA-6809006 https://reactome.org/PathwayBrowser/#/R-CFA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Canis familiaris 37565 R-CFA-6809010 https://reactome.org/PathwayBrowser/#/R-CFA-6809010 COPI vesicle uncoating IEA Canis familiaris 37565 R-CFA-6809011 https://reactome.org/PathwayBrowser/#/R-CFA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Canis familiaris 37565 R-CFA-6811411 https://reactome.org/PathwayBrowser/#/R-CFA-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Canis familiaris 37565 R-CFA-6811412 https://reactome.org/PathwayBrowser/#/R-CFA-6811412 Active ARF recruits coatomer to the Golgi IEA Canis familiaris 37565 R-CFA-6811414 https://reactome.org/PathwayBrowser/#/R-CFA-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Canis familiaris 37565 R-CFA-6811415 https://reactome.org/PathwayBrowser/#/R-CFA-6811415 RAB:GTP recruits GBF1 to the Golgi membrane IEA Canis familiaris 37565 R-CFA-6811417 https://reactome.org/PathwayBrowser/#/R-CFA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Canis familiaris 37565 R-CFA-6811418 https://reactome.org/PathwayBrowser/#/R-CFA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Canis familiaris 37565 R-CFA-6811423 https://reactome.org/PathwayBrowser/#/R-CFA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Canis familiaris 37565 R-CFA-6811426 https://reactome.org/PathwayBrowser/#/R-CFA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Canis familiaris 37565 R-CFA-6811427 https://reactome.org/PathwayBrowser/#/R-CFA-6811427 COPI vesicle uncoating at the ER IEA Canis familiaris 37565 R-CFA-6814086 https://reactome.org/PathwayBrowser/#/R-CFA-6814086 ARFRP1 recruits ARL1 to the TGN IEA Canis familiaris 37565 R-CFA-6814088 https://reactome.org/PathwayBrowser/#/R-CFA-6814088 SYS1 binds AcM-ARFRP1 IEA Canis familiaris 37565 R-CFA-6814091 https://reactome.org/PathwayBrowser/#/R-CFA-6814091 ARL1 recruits TGN Golgin homodimers IEA Canis familiaris 37565 R-CFA-6814094 https://reactome.org/PathwayBrowser/#/R-CFA-6814094 ARL1:GTP binds ARFIP2 IEA Canis familiaris 37565 R-CFA-6814096 https://reactome.org/PathwayBrowser/#/R-CFA-6814096 ARL1:GTP binds SCOC IEA Canis familiaris 37565 R-CFA-6814549 https://reactome.org/PathwayBrowser/#/R-CFA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Canis familiaris 37565 R-CFA-6814559 https://reactome.org/PathwayBrowser/#/R-CFA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Canis familiaris 37565 R-CFA-6814670 https://reactome.org/PathwayBrowser/#/R-CFA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Canis familiaris 37565 R-CFA-6814671 https://reactome.org/PathwayBrowser/#/R-CFA-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Canis familiaris 37565 R-CFA-6814674 https://reactome.org/PathwayBrowser/#/R-CFA-6814674 Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins IEA Canis familiaris 37565 R-CFA-6814675 https://reactome.org/PathwayBrowser/#/R-CFA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Canis familiaris 37565 R-CFA-6814831 https://reactome.org/PathwayBrowser/#/R-CFA-6814831 TBC1D20 binds RAB1:GTP IEA Canis familiaris 37565 R-CFA-6814833 https://reactome.org/PathwayBrowser/#/R-CFA-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Canis familiaris 37565 R-CFA-70241 https://reactome.org/PathwayBrowser/#/R-CFA-70241 PCK1 phosphorylates OA to yield PEP IEA Canis familiaris 37565 R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Canis familiaris 37565 R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Canis familiaris 37565 R-CFA-71775 https://reactome.org/PathwayBrowser/#/R-CFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Canis familiaris 37565 R-CFA-72619 https://reactome.org/PathwayBrowser/#/R-CFA-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Canis familiaris 37565 R-CFA-72621 https://reactome.org/PathwayBrowser/#/R-CFA-72621 Ribosomal scanning IEA Canis familiaris 37565 R-CFA-72663 https://reactome.org/PathwayBrowser/#/R-CFA-72663 De novo formation of eIF2:GTP IEA Canis familiaris 37565 R-CFA-72669 https://reactome.org/PathwayBrowser/#/R-CFA-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Canis familiaris 37565 R-CFA-72671 https://reactome.org/PathwayBrowser/#/R-CFA-72671 eIF5B:GTP is hydrolyzed and released IEA Canis familiaris 37565 R-CFA-72672 https://reactome.org/PathwayBrowser/#/R-CFA-72672 The 60S subunit joins the translation initiation complex IEA Canis familiaris 37565 R-CFA-72691 https://reactome.org/PathwayBrowser/#/R-CFA-72691 Formation of the 43S pre-initiation complex IEA Canis familiaris 37565 R-CFA-72697 https://reactome.org/PathwayBrowser/#/R-CFA-72697 Start codon recognition IEA Canis familiaris 37565 R-CFA-72722 https://reactome.org/PathwayBrowser/#/R-CFA-72722 eIF2 activation IEA Canis familiaris 37565 R-CFA-74059 https://reactome.org/PathwayBrowser/#/R-CFA-74059 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 37565 R-CFA-74885 https://reactome.org/PathwayBrowser/#/R-CFA-74885 GUCYs converts GTP to cGMP IEA Canis familiaris 37565 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 37565 R-CFA-749453 https://reactome.org/PathwayBrowser/#/R-CFA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Canis familiaris 37565 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 37565 R-CFA-751019 https://reactome.org/PathwayBrowser/#/R-CFA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Canis familiaris 37565 R-CFA-751024 https://reactome.org/PathwayBrowser/#/R-CFA-751024 The Ligand:GPCR:Gz complex dissociates IEA Canis familiaris 37565 R-CFA-751029 https://reactome.org/PathwayBrowser/#/R-CFA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Canis familiaris 37565 R-CFA-77081 https://reactome.org/PathwayBrowser/#/R-CFA-77081 Formation of the CE:GMP intermediate complex IEA Canis familiaris 37565 R-CFA-8847887 https://reactome.org/PathwayBrowser/#/R-CFA-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Canis familiaris 37565 R-CFA-8848618 https://reactome.org/PathwayBrowser/#/R-CFA-8848618 Activation of RAC1 by the PXN:CRK complex IEA Canis familiaris 37565 R-CFA-8849082 https://reactome.org/PathwayBrowser/#/R-CFA-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Canis familiaris 37565 R-CFA-8849085 https://reactome.org/PathwayBrowser/#/R-CFA-8849085 ARHGAP35 binds RHOA:GTP IEA Canis familiaris 37565 R-CFA-8849748 https://reactome.org/PathwayBrowser/#/R-CFA-8849748 The COG complex binds RABs at the Golgi membrane IEA Canis familiaris 37565 R-CFA-8850041 https://reactome.org/PathwayBrowser/#/R-CFA-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Canis familiaris 37565 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 37565 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 37565 R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 37565 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 37565 R-CFA-8851827 https://reactome.org/PathwayBrowser/#/R-CFA-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Canis familiaris 37565 R-CFA-8851877 https://reactome.org/PathwayBrowser/#/R-CFA-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Canis familiaris 37565 R-CFA-8851899 https://reactome.org/PathwayBrowser/#/R-CFA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Canis familiaris 37565 R-CFA-8852280 https://reactome.org/PathwayBrowser/#/R-CFA-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Canis familiaris 37565 R-CFA-8852298 https://reactome.org/PathwayBrowser/#/R-CFA-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Canis familiaris 37565 R-CFA-8852306 https://reactome.org/PathwayBrowser/#/R-CFA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Canis familiaris 37565 R-CFA-8854173 https://reactome.org/PathwayBrowser/#/R-CFA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Canis familiaris 37565 R-CFA-8854182 https://reactome.org/PathwayBrowser/#/R-CFA-8854182 TBC1D17 binds OPTN:RAB8A IEA Canis familiaris 37565 R-CFA-8854293 https://reactome.org/PathwayBrowser/#/R-CFA-8854293 TBC1D10A (EPI64) binds ARF6:GTP IEA Canis familiaris 37565 R-CFA-8854612 https://reactome.org/PathwayBrowser/#/R-CFA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Canis familiaris 37565 R-CFA-8856808 https://reactome.org/PathwayBrowser/#/R-CFA-8856808 Recruitment of AP-2 complex and clathrin IEA Canis familiaris 37565 R-CFA-8865774 https://reactome.org/PathwayBrowser/#/R-CFA-8865774 TTLLs polyglutamylate tubulin IEA Canis familiaris 37565 R-CFA-8867370 https://reactome.org/PathwayBrowser/#/R-CFA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Canis familiaris 37565 R-CFA-8868236 https://reactome.org/PathwayBrowser/#/R-CFA-8868236 BAR domain proteins recruit dynamin IEA Canis familiaris 37565 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 37565 R-CFA-8868651 https://reactome.org/PathwayBrowser/#/R-CFA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Canis familiaris 37565 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 37565 R-CFA-8871193 https://reactome.org/PathwayBrowser/#/R-CFA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Canis familiaris 37565 R-CFA-8875318 https://reactome.org/PathwayBrowser/#/R-CFA-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Canis familiaris 37565 R-CFA-8875320 https://reactome.org/PathwayBrowser/#/R-CFA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Canis familiaris 37565 R-CFA-8875568 https://reactome.org/PathwayBrowser/#/R-CFA-8875568 RAPGEF1 activates RAP1 IEA Canis familiaris 37565 R-CFA-8875591 https://reactome.org/PathwayBrowser/#/R-CFA-8875591 DOCK7 activates RAC1 IEA Canis familiaris 37565 R-CFA-8875659 https://reactome.org/PathwayBrowser/#/R-CFA-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Canis familiaris 37565 R-CFA-8875661 https://reactome.org/PathwayBrowser/#/R-CFA-8875661 GGA3 associates with activated MET receptor IEA Canis familiaris 37565 R-CFA-8876188 https://reactome.org/PathwayBrowser/#/R-CFA-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Canis familiaris 37565 R-CFA-8876190 https://reactome.org/PathwayBrowser/#/R-CFA-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Canis familiaris 37565 R-CFA-8876191 https://reactome.org/PathwayBrowser/#/R-CFA-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Canis familiaris 37565 R-CFA-8876454 https://reactome.org/PathwayBrowser/#/R-CFA-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Canis familiaris 37565 R-CFA-8876615 https://reactome.org/PathwayBrowser/#/R-CFA-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Canis familiaris 37565 R-CFA-8877308 https://reactome.org/PathwayBrowser/#/R-CFA-8877308 MADD exchanges GTP for GDP on RAB27 IEA Canis familiaris 37565 R-CFA-8877451 https://reactome.org/PathwayBrowser/#/R-CFA-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Canis familiaris 37565 R-CFA-8877475 https://reactome.org/PathwayBrowser/#/R-CFA-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Canis familiaris 37565 R-CFA-8877612 https://reactome.org/PathwayBrowser/#/R-CFA-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Canis familiaris 37565 R-CFA-8877760 https://reactome.org/PathwayBrowser/#/R-CFA-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Canis familiaris 37565 R-CFA-8877813 https://reactome.org/PathwayBrowser/#/R-CFA-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Canis familiaris 37565 R-CFA-8877998 https://reactome.org/PathwayBrowser/#/R-CFA-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Canis familiaris 37565 R-CFA-8941613 https://reactome.org/PathwayBrowser/#/R-CFA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-8941618 https://reactome.org/PathwayBrowser/#/R-CFA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-8941623 https://reactome.org/PathwayBrowser/#/R-CFA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-8941628 https://reactome.org/PathwayBrowser/#/R-CFA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 37565 R-CFA-8944454 https://reactome.org/PathwayBrowser/#/R-CFA-8944454 mTORC1 phosphorylates MAF1 IEA Canis familiaris 37565 R-CFA-8944457 https://reactome.org/PathwayBrowser/#/R-CFA-8944457 MAF1 translocates to the nucleus IEA Canis familiaris 37565 R-CFA-8951490 https://reactome.org/PathwayBrowser/#/R-CFA-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Canis familiaris 37565 R-CFA-8951498 https://reactome.org/PathwayBrowser/#/R-CFA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Canis familiaris 37565 R-CFA-8952716 https://reactome.org/PathwayBrowser/#/R-CFA-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Canis familiaris 37565 R-CFA-8952726 https://reactome.org/PathwayBrowser/#/R-CFA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Canis familiaris 37565 R-CFA-8964242 https://reactome.org/PathwayBrowser/#/R-CFA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Canis familiaris 37565 R-CFA-8964246 https://reactome.org/PathwayBrowser/#/R-CFA-8964246 BTK in G alpha (12)-BTK complex is activated IEA Canis familiaris 37565 R-CFA-8964274 https://reactome.org/PathwayBrowser/#/R-CFA-8964274 G alpha (12) binds BTK IEA Canis familiaris 37565 R-CFA-8964280 https://reactome.org/PathwayBrowser/#/R-CFA-8964280 Active Gq binds BTK IEA Canis familiaris 37565 R-CFA-8964284 https://reactome.org/PathwayBrowser/#/R-CFA-8964284 BTK in active Gq-BTK complex is activated IEA Canis familiaris 37565 R-CFA-8964329 https://reactome.org/PathwayBrowser/#/R-CFA-8964329 G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC IEA Canis familiaris 37565 R-CFA-8964333 https://reactome.org/PathwayBrowser/#/R-CFA-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) IEA Canis familiaris 37565 R-CFA-8964340 https://reactome.org/PathwayBrowser/#/R-CFA-8964340 Gq-BTK complex dissociates to Active BTK and Gq IEA Canis familiaris 37565 R-CFA-8964599 https://reactome.org/PathwayBrowser/#/R-CFA-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Canis familiaris 37565 R-CFA-8964604 https://reactome.org/PathwayBrowser/#/R-CFA-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Canis familiaris 37565 R-CFA-8964614 https://reactome.org/PathwayBrowser/#/R-CFA-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Canis familiaris 37565 R-CFA-8980691 https://reactome.org/PathwayBrowser/#/R-CFA-8980691 RHOA GEFs activate RHOA IEA Canis familiaris 37565 R-CFA-8981353 https://reactome.org/PathwayBrowser/#/R-CFA-8981353 RASA1 stimulates RAS GTPase activity IEA Canis familiaris 37565 R-CFA-8981355 https://reactome.org/PathwayBrowser/#/R-CFA-8981355 RASA1 binds RAS:GTP IEA Canis familiaris 37565 R-CFA-8981637 https://reactome.org/PathwayBrowser/#/R-CFA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Canis familiaris 37565 R-CFA-8981892 https://reactome.org/PathwayBrowser/#/R-CFA-8981892 Active G alpha (z) binds RGS proteins IEA Canis familiaris 37565 R-CFA-8981926 https://reactome.org/PathwayBrowser/#/R-CFA-8981926 RAC1 and CDC42 activate PAK3 IEA Canis familiaris 37565 R-CFA-8981931 https://reactome.org/PathwayBrowser/#/R-CFA-8981931 RAC1 and CDC42 activate PAK2 IEA Canis familiaris 37565 R-CFA-8982017 https://reactome.org/PathwayBrowser/#/R-CFA-8982017 Active G alpha (q) binds RGS proteins IEA Canis familiaris 37565 R-CFA-8982019 https://reactome.org/PathwayBrowser/#/R-CFA-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Canis familiaris 37565 R-CFA-8982020 https://reactome.org/PathwayBrowser/#/R-CFA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Canis familiaris 37565 R-CFA-8982021 https://reactome.org/PathwayBrowser/#/R-CFA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Canis familiaris 37565 R-CFA-8982025 https://reactome.org/PathwayBrowser/#/R-CFA-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Canis familiaris 37565 R-CFA-8982640 https://reactome.org/PathwayBrowser/#/R-CFA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Canis familiaris 37565 R-CFA-8985594 https://reactome.org/PathwayBrowser/#/R-CFA-8985594 MYO9B inactivates RHOA IEA Canis familiaris 37565 R-CFA-9013004 https://reactome.org/PathwayBrowser/#/R-CFA-9013004 RHOA binds effectors at the ER membrane IEA Canis familiaris 37565 R-CFA-9013006 https://reactome.org/PathwayBrowser/#/R-CFA-9013006 RHOA:GTP translocates to the ER membrane IEA Canis familiaris 37565 R-CFA-9013009 https://reactome.org/PathwayBrowser/#/R-CFA-9013009 RHOA binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9013022 https://reactome.org/PathwayBrowser/#/R-CFA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Canis familiaris 37565 R-CFA-9013023 https://reactome.org/PathwayBrowser/#/R-CFA-9013023 RHOB GEFs activate RHOB IEA Canis familiaris 37565 R-CFA-9013024 https://reactome.org/PathwayBrowser/#/R-CFA-9013024 RHOB binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9013109 https://reactome.org/PathwayBrowser/#/R-CFA-9013109 RHOC GEFs activate RHOC IEA Canis familiaris 37565 R-CFA-9013110 https://reactome.org/PathwayBrowser/#/R-CFA-9013110 RHOC binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9013111 https://reactome.org/PathwayBrowser/#/R-CFA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Canis familiaris 37565 R-CFA-9013143 https://reactome.org/PathwayBrowser/#/R-CFA-9013143 RAC1 GEFs activate RAC1 IEA Canis familiaris 37565 R-CFA-9013144 https://reactome.org/PathwayBrowser/#/R-CFA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Canis familiaris 37565 R-CFA-9013145 https://reactome.org/PathwayBrowser/#/R-CFA-9013145 RAC1 binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9013157 https://reactome.org/PathwayBrowser/#/R-CFA-9013157 CDC42 binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9013159 https://reactome.org/PathwayBrowser/#/R-CFA-9013159 CDC42 GEFs activate CDC42 IEA Canis familiaris 37565 R-CFA-9013161 https://reactome.org/PathwayBrowser/#/R-CFA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Canis familiaris 37565 R-CFA-9013435 https://reactome.org/PathwayBrowser/#/R-CFA-9013435 RHOD auto-activates IEA Canis familiaris 37565 R-CFA-9013437 https://reactome.org/PathwayBrowser/#/R-CFA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Canis familiaris 37565 R-CFA-9013438 https://reactome.org/PathwayBrowser/#/R-CFA-9013438 RHOD binds effectors at the endosome membrane IEA Canis familiaris 37565 R-CFA-9013452 https://reactome.org/PathwayBrowser/#/R-CFA-9013452 RHOD:GTP translocates to the endosome membrane IEA Canis familiaris 37565 R-CFA-9014294 https://reactome.org/PathwayBrowser/#/R-CFA-9014294 RAC2 binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9014295 https://reactome.org/PathwayBrowser/#/R-CFA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Canis familiaris 37565 R-CFA-9014296 https://reactome.org/PathwayBrowser/#/R-CFA-9014296 RAC2 GEFs activate RAC2 IEA Canis familiaris 37565 R-CFA-9014420 https://reactome.org/PathwayBrowser/#/R-CFA-9014420 RAC2 translocates to the phagocytic vesicle membrane IEA Canis familiaris 37565 R-CFA-9014424 https://reactome.org/PathwayBrowser/#/R-CFA-9014424 RAC2 binds effectors at the phagocytic vesicle membrane IEA Canis familiaris 37565 R-CFA-9014433 https://reactome.org/PathwayBrowser/#/R-CFA-9014433 RHOG GEFs activate RHOG IEA Canis familiaris 37565 R-CFA-9014434 https://reactome.org/PathwayBrowser/#/R-CFA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Canis familiaris 37565 R-CFA-9014449 https://reactome.org/PathwayBrowser/#/R-CFA-9014449 RHOG binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9014454 https://reactome.org/PathwayBrowser/#/R-CFA-9014454 RHOG translocates to the ER membrane IEA Canis familiaris 37565 R-CFA-9014467 https://reactome.org/PathwayBrowser/#/R-CFA-9014467 RHOG binds effectors at the ER membrane IEA Canis familiaris 37565 R-CFA-9017488 https://reactome.org/PathwayBrowser/#/R-CFA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Canis familiaris 37565 R-CFA-9017491 https://reactome.org/PathwayBrowser/#/R-CFA-9017491 RHOJ GEFs activate RHOJ IEA Canis familiaris 37565 R-CFA-9018745 https://reactome.org/PathwayBrowser/#/R-CFA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Canis familiaris 37565 R-CFA-9018746 https://reactome.org/PathwayBrowser/#/R-CFA-9018746 RHOQ binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9018747 https://reactome.org/PathwayBrowser/#/R-CFA-9018747 RHOQ GEFs activate RHOQ IEA Canis familiaris 37565 R-CFA-9018754 https://reactome.org/PathwayBrowser/#/R-CFA-9018754 GDIs bind RHOH IEA Canis familiaris 37565 R-CFA-9018756 https://reactome.org/PathwayBrowser/#/R-CFA-9018756 RHOH binds GTP IEA Canis familiaris 37565 R-CFA-9018758 https://reactome.org/PathwayBrowser/#/R-CFA-9018758 RHOH binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9018766 https://reactome.org/PathwayBrowser/#/R-CFA-9018766 RHOU binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9018768 https://reactome.org/PathwayBrowser/#/R-CFA-9018768 RHOU auto-activates IEA Canis familiaris 37565 R-CFA-9018774 https://reactome.org/PathwayBrowser/#/R-CFA-9018774 RHOBTB1 binds GTP IEA Canis familiaris 37565 R-CFA-9018778 https://reactome.org/PathwayBrowser/#/R-CFA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Canis familiaris 37565 R-CFA-9018785 https://reactome.org/PathwayBrowser/#/R-CFA-9018785 RHOBTB2 binds GTP IEA Canis familiaris 37565 R-CFA-9018787 https://reactome.org/PathwayBrowser/#/R-CFA-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Canis familiaris 37565 R-CFA-9018794 https://reactome.org/PathwayBrowser/#/R-CFA-9018794 RHOV binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9018798 https://reactome.org/PathwayBrowser/#/R-CFA-9018798 RHOV binds GTP IEA Canis familiaris 37565 R-CFA-9018804 https://reactome.org/PathwayBrowser/#/R-CFA-9018804 RAC3 GEFs activate RAC3 IEA Canis familiaris 37565 R-CFA-9018806 https://reactome.org/PathwayBrowser/#/R-CFA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Canis familiaris 37565 R-CFA-9018808 https://reactome.org/PathwayBrowser/#/R-CFA-9018808 RAC3 binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9018814 https://reactome.org/PathwayBrowser/#/R-CFA-9018814 RHOT1 hydrolyzes GTP IEA Canis familiaris 37565 R-CFA-9018815 https://reactome.org/PathwayBrowser/#/R-CFA-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Canis familiaris 37565 R-CFA-9018836 https://reactome.org/PathwayBrowser/#/R-CFA-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Canis familiaris 37565 R-CFA-9032798 https://reactome.org/PathwayBrowser/#/R-CFA-9032798 DOCK3 activates RAC1 IEA Canis familiaris 37565 R-CFA-9036301 https://reactome.org/PathwayBrowser/#/R-CFA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Canis familiaris 37565 R-CFA-939265 https://reactome.org/PathwayBrowser/#/R-CFA-939265 Activation of Rap1 by membrane-associated GEFs IEA Canis familiaris 37565 R-CFA-947535 https://reactome.org/PathwayBrowser/#/R-CFA-947535 Cyclisation of GTP to precursor Z IEA Canis familiaris 37565 R-CFA-9607304 https://reactome.org/PathwayBrowser/#/R-CFA-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Canis familiaris 37565 R-CFA-9624845 https://reactome.org/PathwayBrowser/#/R-CFA-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Canis familiaris 37565 R-CFA-9624876 https://reactome.org/PathwayBrowser/#/R-CFA-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Canis familiaris 37565 R-CFA-9624893 https://reactome.org/PathwayBrowser/#/R-CFA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Canis familiaris 37565 R-CFA-9626848 https://reactome.org/PathwayBrowser/#/R-CFA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Canis familiaris 37565 R-CFA-9632910 https://reactome.org/PathwayBrowser/#/R-CFA-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Canis familiaris 37565 R-CFA-9632918 https://reactome.org/PathwayBrowser/#/R-CFA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Canis familiaris 37565 R-CFA-9639286 https://reactome.org/PathwayBrowser/#/R-CFA-9639286 RRAGC,D exchanges GTP for GDP IEA Canis familiaris 37565 R-CFA-9640167 https://reactome.org/PathwayBrowser/#/R-CFA-9640167 RRAGA,B exchanges GDP for GTP IEA Canis familiaris 37565 R-CFA-9640168 https://reactome.org/PathwayBrowser/#/R-CFA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Canis familiaris 37565 R-CFA-9640195 https://reactome.org/PathwayBrowser/#/R-CFA-9640195 RRAGA,B hydrolyzes GTP IEA Canis familiaris 37565 R-CFA-9645598 https://reactome.org/PathwayBrowser/#/R-CFA-9645598 RRAGC,D hydrolyzes GTP IEA Canis familiaris 37565 R-CFA-9645608 https://reactome.org/PathwayBrowser/#/R-CFA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Canis familiaris 37565 R-CFA-9646468 https://reactome.org/PathwayBrowser/#/R-CFA-9646468 mTORC1 binds RHEB:GTP IEA Canis familiaris 37565 R-CFA-9646679 https://reactome.org/PathwayBrowser/#/R-CFA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Canis familiaris 37565 R-CFA-9646685 https://reactome.org/PathwayBrowser/#/R-CFA-9646685 Aggresome dissociates from dynein and microtubule IEA Canis familiaris 37565 R-CFA-9648017 https://reactome.org/PathwayBrowser/#/R-CFA-9648017 EML4 binds to microtubules IEA Canis familiaris 37565 R-CFA-9648114 https://reactome.org/PathwayBrowser/#/R-CFA-9648114 EML4 recruits NUDC to mitotic spindle IEA Canis familiaris 37565 R-CFA-9649735 https://reactome.org/PathwayBrowser/#/R-CFA-9649735 Intrinsic nucleotide exchange on RAS IEA Canis familiaris 37565 R-CFA-9649736 https://reactome.org/PathwayBrowser/#/R-CFA-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Canis familiaris 37565 R-CFA-9653108 https://reactome.org/PathwayBrowser/#/R-CFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Canis familiaris 37565 R-CFA-9654523 https://reactome.org/PathwayBrowser/#/R-CFA-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Canis familiaris 37565 R-CFA-9654533 https://reactome.org/PathwayBrowser/#/R-CFA-9654533 KRAS4B recycles to the plasma membrane IEA Canis familiaris 37565 R-CFA-9657599 https://reactome.org/PathwayBrowser/#/R-CFA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Canis familiaris 37565 R-CFA-9657603 https://reactome.org/PathwayBrowser/#/R-CFA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Canis familiaris 37565 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 37565 R-CFA-9657608 https://reactome.org/PathwayBrowser/#/R-CFA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Canis familiaris 37565 R-CFA-9658253 https://reactome.org/PathwayBrowser/#/R-CFA-9658253 RAS:GTP binds PI3K IEA Canis familiaris 37565 R-CFA-9660557 https://reactome.org/PathwayBrowser/#/R-CFA-9660557 RAS:GTP binds RAL GDS proteins IEA Canis familiaris 37565 R-CFA-9668419 https://reactome.org/PathwayBrowser/#/R-CFA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Canis familiaris 37565 R-CFA-9690493 https://reactome.org/PathwayBrowser/#/R-CFA-9690493 RHOB binds effectors on endosomes IEA Canis familiaris 37565 R-CFA-9690494 https://reactome.org/PathwayBrowser/#/R-CFA-9690494 RHOB translocates to the endosome membrane IEA Canis familiaris 37565 R-CFA-9691168 https://reactome.org/PathwayBrowser/#/R-CFA-9691168 RAC1 translocates to the endoplasmic reticulum membrane IEA Canis familiaris 37565 R-CFA-9691174 https://reactome.org/PathwayBrowser/#/R-CFA-9691174 RAC1 binds effectors at the ER membrane IEA Canis familiaris 37565 R-CFA-9692800 https://reactome.org/PathwayBrowser/#/R-CFA-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Canis familiaris 37565 R-CFA-9692809 https://reactome.org/PathwayBrowser/#/R-CFA-9692809 CDC42 binds effectors at the ER membrane IEA Canis familiaris 37565 R-CFA-9693111 https://reactome.org/PathwayBrowser/#/R-CFA-9693111 RHOF auto-activates IEA Canis familiaris 37565 R-CFA-9693125 https://reactome.org/PathwayBrowser/#/R-CFA-9693125 RHOF binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9693198 https://reactome.org/PathwayBrowser/#/R-CFA-9693198 RHOD binds effectors at the plasma membrane IEA Canis familiaris 37565 R-CFA-9693207 https://reactome.org/PathwayBrowser/#/R-CFA-9693207 RHOD translocates to the mitochondrial outer membrane IEA Canis familiaris 37565 R-CFA-9693214 https://reactome.org/PathwayBrowser/#/R-CFA-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Canis familiaris 37565 R-CFA-9693243 https://reactome.org/PathwayBrowser/#/R-CFA-9693243 RHOD translocates to the Golgi membrane IEA Canis familiaris 37565 R-CFA-9693250 https://reactome.org/PathwayBrowser/#/R-CFA-9693250 RHOD binds effectors at the Golgi membrane IEA Canis familiaris 37565 R-CFA-9693282 https://reactome.org/PathwayBrowser/#/R-CFA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Canis familiaris 37565 R-CFA-9696266 https://reactome.org/PathwayBrowser/#/R-CFA-9696266 RND2 binds effectors IEA Canis familiaris 37565 R-CFA-9696267 https://reactome.org/PathwayBrowser/#/R-CFA-9696267 RND3 binds GTP IEA Canis familiaris 37565 R-CFA-9696268 https://reactome.org/PathwayBrowser/#/R-CFA-9696268 RND3 binds effectors IEA Canis familiaris 37565 R-CFA-9696271 https://reactome.org/PathwayBrowser/#/R-CFA-9696271 RND1 binds effectors IEA Canis familiaris 37565 R-CFA-9696274 https://reactome.org/PathwayBrowser/#/R-CFA-9696274 RND1 binds GTP IEA Canis familiaris 37565 R-CFA-9696275 https://reactome.org/PathwayBrowser/#/R-CFA-9696275 RND2 binds GTP IEA Canis familiaris 37565 R-CFA-9714361 https://reactome.org/PathwayBrowser/#/R-CFA-9714361 RHOC activates endoplasmic reticulum effectors IEA Canis familiaris 37565 R-CFA-9714363 https://reactome.org/PathwayBrowser/#/R-CFA-9714363 RHOC translocates to the endoplasmic reticulum membrane IEA Canis familiaris 37565 R-CFA-9714477 https://reactome.org/PathwayBrowser/#/R-CFA-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Canis familiaris 37565 R-CFA-9714480 https://reactome.org/PathwayBrowser/#/R-CFA-9714480 RAC2 translocates to the mitochondrial membrane IEA Canis familiaris 37565 R-CFA-9714481 https://reactome.org/PathwayBrowser/#/R-CFA-9714481 RAC2 binds effectors at the ER membrane IEA Canis familiaris 37565 R-CFA-9714483 https://reactome.org/PathwayBrowser/#/R-CFA-9714483 RAC2 translocates to the ER membrane IEA Canis familiaris 37565 R-CFA-9714691 https://reactome.org/PathwayBrowser/#/R-CFA-9714691 RAC3 binds ER effectors IEA Canis familiaris 37565 R-CFA-9714694 https://reactome.org/PathwayBrowser/#/R-CFA-9714694 RAC3 translocates to the endoplasmic reticulum membrane IEA Canis familiaris 37565 R-CFA-983259 https://reactome.org/PathwayBrowser/#/R-CFA-983259 Kinesins move along microtubules consuming ATP IEA Canis familiaris 37565 R-CFA-983266 https://reactome.org/PathwayBrowser/#/R-CFA-983266 Kinesins bind microtubules IEA Canis familiaris 37565 R-CFA-983422 https://reactome.org/PathwayBrowser/#/R-CFA-983422 Disassembly of COPII coated vesicle IEA Canis familiaris 37565 R-CFA-983424 https://reactome.org/PathwayBrowser/#/R-CFA-983424 Budding of COPII coated vesicle IEA Canis familiaris 37565 R-CFA-983425 https://reactome.org/PathwayBrowser/#/R-CFA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Canis familiaris 37565 R-CFA-9836404 https://reactome.org/PathwayBrowser/#/R-CFA-9836404 p-PKR dimer phosphorylates MAPT IEA Canis familiaris 37565 R-DDI-1008248 https://reactome.org/PathwayBrowser/#/R-DDI-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Dictyostelium discoideum 37565 R-DDI-111524 https://reactome.org/PathwayBrowser/#/R-DDI-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Dictyostelium discoideum 37565 R-DDI-111879 https://reactome.org/PathwayBrowser/#/R-DDI-111879 PIP2 hydrolysis IEA Dictyostelium discoideum 37565 R-DDI-112037 https://reactome.org/PathwayBrowser/#/R-DDI-112037 Inactivation of PLC beta IEA Dictyostelium discoideum 37565 R-DDI-114688 https://reactome.org/PathwayBrowser/#/R-DDI-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Dictyostelium discoideum 37565 R-DDI-1474146 https://reactome.org/PathwayBrowser/#/R-DDI-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Dictyostelium discoideum 37565 R-DDI-156823 https://reactome.org/PathwayBrowser/#/R-DDI-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Dictyostelium discoideum 37565 R-DDI-156913 https://reactome.org/PathwayBrowser/#/R-DDI-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Dictyostelium discoideum 37565 R-DDI-156930 https://reactome.org/PathwayBrowser/#/R-DDI-156930 GTP-binding activates eEF2 IEA Dictyostelium discoideum 37565 R-DDI-165195 https://reactome.org/PathwayBrowser/#/R-DDI-165195 GTP loading by Rheb IEA Dictyostelium discoideum 37565 R-DDI-165680 https://reactome.org/PathwayBrowser/#/R-DDI-165680 Formation of active mTORC1 complex IEA Dictyostelium discoideum 37565 R-DDI-165692 https://reactome.org/PathwayBrowser/#/R-DDI-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Dictyostelium discoideum 37565 R-DDI-165718 https://reactome.org/PathwayBrowser/#/R-DDI-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Dictyostelium discoideum 37565 R-DDI-167415 https://reactome.org/PathwayBrowser/#/R-DDI-167415 G-protein alpha subunit is inactivated IEA Dictyostelium discoideum 37565 R-DDI-170666 https://reactome.org/PathwayBrowser/#/R-DDI-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Dictyostelium discoideum 37565 R-DDI-170671 https://reactome.org/PathwayBrowser/#/R-DDI-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Dictyostelium discoideum 37565 R-DDI-170672 https://reactome.org/PathwayBrowser/#/R-DDI-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Dictyostelium discoideum 37565 R-DDI-170676 https://reactome.org/PathwayBrowser/#/R-DDI-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Dictyostelium discoideum 37565 R-DDI-170685 https://reactome.org/PathwayBrowser/#/R-DDI-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Dictyostelium discoideum 37565 R-DDI-170686 https://reactome.org/PathwayBrowser/#/R-DDI-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Dictyostelium discoideum 37565 R-DDI-2029454 https://reactome.org/PathwayBrowser/#/R-DDI-2029454 Autophosphorylation of PAK1 IEA Dictyostelium discoideum 37565 R-DDI-2029456 https://reactome.org/PathwayBrowser/#/R-DDI-2029456 RAC1 and CDC42 activate PAK1 IEA Dictyostelium discoideum 37565 R-DDI-2029466 https://reactome.org/PathwayBrowser/#/R-DDI-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Dictyostelium discoideum 37565 R-DDI-2029469 https://reactome.org/PathwayBrowser/#/R-DDI-2029469 p-ERK phosphorylates WAVEs and ABI IEA Dictyostelium discoideum 37565 R-DDI-203977 https://reactome.org/PathwayBrowser/#/R-DDI-203977 SAR1 Activation And Membrane Binding IEA Dictyostelium discoideum 37565 R-DDI-203979 https://reactome.org/PathwayBrowser/#/R-DDI-203979 Coat Assembly IEA Dictyostelium discoideum 37565 R-DDI-204008 https://reactome.org/PathwayBrowser/#/R-DDI-204008 SEC31:SEC13 and v-SNARE recruitment IEA Dictyostelium discoideum 37565 R-DDI-205039 https://reactome.org/PathwayBrowser/#/R-DDI-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Dictyostelium discoideum 37565 R-DDI-205136 https://reactome.org/PathwayBrowser/#/R-DDI-205136 GTP-bound RAC contributes to JNK activation IEA Dictyostelium discoideum 37565 R-DDI-2197690 https://reactome.org/PathwayBrowser/#/R-DDI-2197690 Detachment of WASP/WAVE IEA Dictyostelium discoideum 37565 R-DDI-2214351 https://reactome.org/PathwayBrowser/#/R-DDI-2214351 PLK1 phosphorylates GORASP1 IEA Dictyostelium discoideum 37565 R-DDI-350769 https://reactome.org/PathwayBrowser/#/R-DDI-350769 trans-Golgi Network Coat Activation IEA Dictyostelium discoideum 37565 R-DDI-354173 https://reactome.org/PathwayBrowser/#/R-DDI-354173 Activation of Rap1 by cytosolic GEFs IEA Dictyostelium discoideum 37565 R-DDI-372819 https://reactome.org/PathwayBrowser/#/R-DDI-372819 PCK2 phosphorylates OA to yield PEP IEA Dictyostelium discoideum 37565 R-DDI-377186 https://reactome.org/PathwayBrowser/#/R-DDI-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Dictyostelium discoideum 37565 R-DDI-380073 https://reactome.org/PathwayBrowser/#/R-DDI-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Dictyostelium discoideum 37565 R-DDI-380979 https://reactome.org/PathwayBrowser/#/R-DDI-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Dictyostelium discoideum 37565 R-DDI-381727 https://reactome.org/PathwayBrowser/#/R-DDI-381727 RAP1A exchanges GDP for GTP IEA Dictyostelium discoideum 37565 R-DDI-389788 https://reactome.org/PathwayBrowser/#/R-DDI-389788 Activation of PAKs by RAC1 and CDC42 IEA Dictyostelium discoideum 37565 R-DDI-392064 https://reactome.org/PathwayBrowser/#/R-DDI-392064 G alpha (z) inhibits adenylate cyclase IEA Dictyostelium discoideum 37565 R-DDI-392513 https://reactome.org/PathwayBrowser/#/R-DDI-392513 Rap1 signal termination by Rap1GAPs IEA Dictyostelium discoideum 37565 R-DDI-3928619 https://reactome.org/PathwayBrowser/#/R-DDI-3928619 PAK1 binds RAC1:GTP IEA Dictyostelium discoideum 37565 R-DDI-3928620 https://reactome.org/PathwayBrowser/#/R-DDI-3928620 PAK1 autophosphorylates IEA Dictyostelium discoideum 37565 R-DDI-399998 https://reactome.org/PathwayBrowser/#/R-DDI-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Dictyostelium discoideum 37565 R-DDI-418574 https://reactome.org/PathwayBrowser/#/R-DDI-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Dictyostelium discoideum 37565 R-DDI-418582 https://reactome.org/PathwayBrowser/#/R-DDI-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Dictyostelium discoideum 37565 R-DDI-428941 https://reactome.org/PathwayBrowser/#/R-DDI-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Dictyostelium discoideum 37565 R-DDI-445072 https://reactome.org/PathwayBrowser/#/R-DDI-445072 Interaction of PAK1 with Rac1-GTP IEA Dictyostelium discoideum 37565 R-DDI-447074 https://reactome.org/PathwayBrowser/#/R-DDI-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Dictyostelium discoideum 37565 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 37565 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 37565 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 37565 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 37565 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 37565 R-DDI-5610733 https://reactome.org/PathwayBrowser/#/R-DDI-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Dictyostelium discoideum 37565 R-DDI-5618331 https://reactome.org/PathwayBrowser/#/R-DDI-5618331 HDAC6 deacetylates microtubules IEA Dictyostelium discoideum 37565 R-DDI-5623508 https://reactome.org/PathwayBrowser/#/R-DDI-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Dictyostelium discoideum 37565 R-DDI-5626469 https://reactome.org/PathwayBrowser/#/R-DDI-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Dictyostelium discoideum 37565 R-DDI-5626507 https://reactome.org/PathwayBrowser/#/R-DDI-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Dictyostelium discoideum 37565 R-DDI-5626549 https://reactome.org/PathwayBrowser/#/R-DDI-5626549 IQGAPs bind CALM1 IEA Dictyostelium discoideum 37565 R-DDI-5627775 https://reactome.org/PathwayBrowser/#/R-DDI-5627775 Autophosphorylation of PAK1,2,3 IEA Dictyostelium discoideum 37565 R-DDI-5653957 https://reactome.org/PathwayBrowser/#/R-DDI-5653957 Rag dimer formation IEA Dictyostelium discoideum 37565 R-DDI-5653968 https://reactome.org/PathwayBrowser/#/R-DDI-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Dictyostelium discoideum 37565 R-DDI-5653974 https://reactome.org/PathwayBrowser/#/R-DDI-5653974 Ragulator binds Rag dimers IEA Dictyostelium discoideum 37565 R-DDI-5672010 https://reactome.org/PathwayBrowser/#/R-DDI-5672010 Active MTORC1 phosphorylates ULK1 IEA Dictyostelium discoideum 37565 R-DDI-5672017 https://reactome.org/PathwayBrowser/#/R-DDI-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Dictyostelium discoideum 37565 R-DDI-5672329 https://reactome.org/PathwayBrowser/#/R-DDI-5672329 IQGAP1 binds CLIP1 and microtubules IEA Dictyostelium discoideum 37565 R-DDI-5672817 https://reactome.org/PathwayBrowser/#/R-DDI-5672817 Active MTORC1 binds the ULK1 complex IEA Dictyostelium discoideum 37565 R-DDI-5672828 https://reactome.org/PathwayBrowser/#/R-DDI-5672828 mTORC1 phosphorylates AKT1S1 IEA Dictyostelium discoideum 37565 R-DDI-5673768 https://reactome.org/PathwayBrowser/#/R-DDI-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Dictyostelium discoideum 37565 R-DDI-5675790 https://reactome.org/PathwayBrowser/#/R-DDI-5675790 MTORC1 dissociates from ULK complex IEA Dictyostelium discoideum 37565 R-DDI-5694409 https://reactome.org/PathwayBrowser/#/R-DDI-5694409 Nucleotide exchange on RAB1 IEA Dictyostelium discoideum 37565 R-DDI-5694441 https://reactome.org/PathwayBrowser/#/R-DDI-5694441 CSNK1D phosphorylates SEC23 IEA Dictyostelium discoideum 37565 R-DDI-5694522 https://reactome.org/PathwayBrowser/#/R-DDI-5694522 Inner coat assembly and cargo binding IEA Dictyostelium discoideum 37565 R-DDI-5694527 https://reactome.org/PathwayBrowser/#/R-DDI-5694527 Loss of SAR1B GTPase IEA Dictyostelium discoideum 37565 R-DDI-6787533 https://reactome.org/PathwayBrowser/#/R-DDI-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Dictyostelium discoideum 37565 R-DDI-6800138 https://reactome.org/PathwayBrowser/#/R-DDI-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Dictyostelium discoideum 37565 R-DDI-6807864 https://reactome.org/PathwayBrowser/#/R-DDI-6807864 RAB1:GTP recruits GBF1 to the ERGIC IEA Dictyostelium discoideum 37565 R-DDI-6807866 https://reactome.org/PathwayBrowser/#/R-DDI-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Dictyostelium discoideum 37565 R-DDI-6807868 https://reactome.org/PathwayBrowser/#/R-DDI-6807868 GBF1 stimulates ARF nucleotide exchange IEA Dictyostelium discoideum 37565 R-DDI-6807872 https://reactome.org/PathwayBrowser/#/R-DDI-6807872 Active ARF recruits coatomer IEA Dictyostelium discoideum 37565 R-DDI-6807875 https://reactome.org/PathwayBrowser/#/R-DDI-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Dictyostelium discoideum 37565 R-DDI-6807877 https://reactome.org/PathwayBrowser/#/R-DDI-6807877 ARFGAPs stimulate ARF GTPase activity IEA Dictyostelium discoideum 37565 R-DDI-6809003 https://reactome.org/PathwayBrowser/#/R-DDI-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Dictyostelium discoideum 37565 R-DDI-6809011 https://reactome.org/PathwayBrowser/#/R-DDI-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Dictyostelium discoideum 37565 R-DDI-6811411 https://reactome.org/PathwayBrowser/#/R-DDI-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Dictyostelium discoideum 37565 R-DDI-6811412 https://reactome.org/PathwayBrowser/#/R-DDI-6811412 Active ARF recruits coatomer to the Golgi IEA Dictyostelium discoideum 37565 R-DDI-6811414 https://reactome.org/PathwayBrowser/#/R-DDI-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Dictyostelium discoideum 37565 R-DDI-6811415 https://reactome.org/PathwayBrowser/#/R-DDI-6811415 RAB:GTP recruits GBF1 to the Golgi membrane IEA Dictyostelium discoideum 37565 R-DDI-6811417 https://reactome.org/PathwayBrowser/#/R-DDI-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Dictyostelium discoideum 37565 R-DDI-6811418 https://reactome.org/PathwayBrowser/#/R-DDI-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Dictyostelium discoideum 37565 R-DDI-6811427 https://reactome.org/PathwayBrowser/#/R-DDI-6811427 COPI vesicle uncoating at the ER IEA Dictyostelium discoideum 37565 R-DDI-6811429 https://reactome.org/PathwayBrowser/#/R-DDI-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Dictyostelium discoideum 37565 R-DDI-6814086 https://reactome.org/PathwayBrowser/#/R-DDI-6814086 ARFRP1 recruits ARL1 to the TGN IEA Dictyostelium discoideum 37565 R-DDI-6814088 https://reactome.org/PathwayBrowser/#/R-DDI-6814088 SYS1 binds AcM-ARFRP1 IEA Dictyostelium discoideum 37565 R-DDI-6814091 https://reactome.org/PathwayBrowser/#/R-DDI-6814091 ARL1 recruits TGN Golgin homodimers IEA Dictyostelium discoideum 37565 R-DDI-6814559 https://reactome.org/PathwayBrowser/#/R-DDI-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Dictyostelium discoideum 37565 R-DDI-6814831 https://reactome.org/PathwayBrowser/#/R-DDI-6814831 TBC1D20 binds RAB1:GTP IEA Dictyostelium discoideum 37565 R-DDI-6814833 https://reactome.org/PathwayBrowser/#/R-DDI-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Dictyostelium discoideum 37565 R-DDI-70241 https://reactome.org/PathwayBrowser/#/R-DDI-70241 PCK1 phosphorylates OA to yield PEP IEA Dictyostelium discoideum 37565 R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Dictyostelium discoideum 37565 R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Dictyostelium discoideum 37565 R-DDI-71775 https://reactome.org/PathwayBrowser/#/R-DDI-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Dictyostelium discoideum 37565 R-DDI-72621 https://reactome.org/PathwayBrowser/#/R-DDI-72621 Ribosomal scanning IEA Dictyostelium discoideum 37565 R-DDI-72663 https://reactome.org/PathwayBrowser/#/R-DDI-72663 De novo formation of eIF2:GTP IEA Dictyostelium discoideum 37565 R-DDI-72669 https://reactome.org/PathwayBrowser/#/R-DDI-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Dictyostelium discoideum 37565 R-DDI-72671 https://reactome.org/PathwayBrowser/#/R-DDI-72671 eIF5B:GTP is hydrolyzed and released IEA Dictyostelium discoideum 37565 R-DDI-72672 https://reactome.org/PathwayBrowser/#/R-DDI-72672 The 60S subunit joins the translation initiation complex IEA Dictyostelium discoideum 37565 R-DDI-72691 https://reactome.org/PathwayBrowser/#/R-DDI-72691 Formation of the 43S pre-initiation complex IEA Dictyostelium discoideum 37565 R-DDI-72697 https://reactome.org/PathwayBrowser/#/R-DDI-72697 Start codon recognition IEA Dictyostelium discoideum 37565 R-DDI-72722 https://reactome.org/PathwayBrowser/#/R-DDI-72722 eIF2 activation IEA Dictyostelium discoideum 37565 R-DDI-74885 https://reactome.org/PathwayBrowser/#/R-DDI-74885 GUCYs converts GTP to cGMP IEA Dictyostelium discoideum 37565 R-DDI-77081 https://reactome.org/PathwayBrowser/#/R-DDI-77081 Formation of the CE:GMP intermediate complex IEA Dictyostelium discoideum 37565 R-DDI-8847534 https://reactome.org/PathwayBrowser/#/R-DDI-8847534 RAB43 hydrolyses GTP IEA Dictyostelium discoideum 37565 R-DDI-8847537 https://reactome.org/PathwayBrowser/#/R-DDI-8847537 RAB43:GTP binds USP8NL IEA Dictyostelium discoideum 37565 R-DDI-8847887 https://reactome.org/PathwayBrowser/#/R-DDI-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Dictyostelium discoideum 37565 R-DDI-8848618 https://reactome.org/PathwayBrowser/#/R-DDI-8848618 Activation of RAC1 by the PXN:CRK complex IEA Dictyostelium discoideum 37565 R-DDI-8849748 https://reactome.org/PathwayBrowser/#/R-DDI-8849748 The COG complex binds RABs at the Golgi membrane IEA Dictyostelium discoideum 37565 R-DDI-8850041 https://reactome.org/PathwayBrowser/#/R-DDI-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Dictyostelium discoideum 37565 R-DDI-8854173 https://reactome.org/PathwayBrowser/#/R-DDI-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Dictyostelium discoideum 37565 R-DDI-8854612 https://reactome.org/PathwayBrowser/#/R-DDI-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Dictyostelium discoideum 37565 R-DDI-8867370 https://reactome.org/PathwayBrowser/#/R-DDI-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Dictyostelium discoideum 37565 R-DDI-8875320 https://reactome.org/PathwayBrowser/#/R-DDI-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Dictyostelium discoideum 37565 R-DDI-8876191 https://reactome.org/PathwayBrowser/#/R-DDI-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Dictyostelium discoideum 37565 R-DDI-8876193 https://reactome.org/PathwayBrowser/#/R-DDI-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Dictyostelium discoideum 37565 R-DDI-8876454 https://reactome.org/PathwayBrowser/#/R-DDI-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Dictyostelium discoideum 37565 R-DDI-8876615 https://reactome.org/PathwayBrowser/#/R-DDI-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Dictyostelium discoideum 37565 R-DDI-8876616 https://reactome.org/PathwayBrowser/#/R-DDI-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Dictyostelium discoideum 37565 R-DDI-8876837 https://reactome.org/PathwayBrowser/#/R-DDI-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Dictyostelium discoideum 37565 R-DDI-8877451 https://reactome.org/PathwayBrowser/#/R-DDI-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Dictyostelium discoideum 37565 R-DDI-8877475 https://reactome.org/PathwayBrowser/#/R-DDI-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Dictyostelium discoideum 37565 R-DDI-8877612 https://reactome.org/PathwayBrowser/#/R-DDI-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Dictyostelium discoideum 37565 R-DDI-8877998 https://reactome.org/PathwayBrowser/#/R-DDI-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Dictyostelium discoideum 37565 R-DDI-8944454 https://reactome.org/PathwayBrowser/#/R-DDI-8944454 mTORC1 phosphorylates MAF1 IEA Dictyostelium discoideum 37565 R-DDI-8944457 https://reactome.org/PathwayBrowser/#/R-DDI-8944457 MAF1 translocates to the nucleus IEA Dictyostelium discoideum 37565 R-DDI-8952726 https://reactome.org/PathwayBrowser/#/R-DDI-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Dictyostelium discoideum 37565 R-DDI-8981892 https://reactome.org/PathwayBrowser/#/R-DDI-8981892 Active G alpha (z) binds RGS proteins IEA Dictyostelium discoideum 37565 R-DDI-8981926 https://reactome.org/PathwayBrowser/#/R-DDI-8981926 RAC1 and CDC42 activate PAK3 IEA Dictyostelium discoideum 37565 R-DDI-8981931 https://reactome.org/PathwayBrowser/#/R-DDI-8981931 RAC1 and CDC42 activate PAK2 IEA Dictyostelium discoideum 37565 R-DDI-8982017 https://reactome.org/PathwayBrowser/#/R-DDI-8982017 Active G alpha (q) binds RGS proteins IEA Dictyostelium discoideum 37565 R-DDI-8982019 https://reactome.org/PathwayBrowser/#/R-DDI-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Dictyostelium discoideum 37565 R-DDI-8982020 https://reactome.org/PathwayBrowser/#/R-DDI-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Dictyostelium discoideum 37565 R-DDI-8982021 https://reactome.org/PathwayBrowser/#/R-DDI-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Dictyostelium discoideum 37565 R-DDI-8982025 https://reactome.org/PathwayBrowser/#/R-DDI-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Dictyostelium discoideum 37565 R-DDI-9013143 https://reactome.org/PathwayBrowser/#/R-DDI-9013143 RAC1 GEFs activate RAC1 IEA Dictyostelium discoideum 37565 R-DDI-9013144 https://reactome.org/PathwayBrowser/#/R-DDI-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Dictyostelium discoideum 37565 R-DDI-9013145 https://reactome.org/PathwayBrowser/#/R-DDI-9013145 RAC1 binds effectors at the plasma membrane IEA Dictyostelium discoideum 37565 R-DDI-9013159 https://reactome.org/PathwayBrowser/#/R-DDI-9013159 CDC42 GEFs activate CDC42 IEA Dictyostelium discoideum 37565 R-DDI-9013161 https://reactome.org/PathwayBrowser/#/R-DDI-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Dictyostelium discoideum 37565 R-DDI-9014294 https://reactome.org/PathwayBrowser/#/R-DDI-9014294 RAC2 binds effectors at the plasma membrane IEA Dictyostelium discoideum 37565 R-DDI-9014295 https://reactome.org/PathwayBrowser/#/R-DDI-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Dictyostelium discoideum 37565 R-DDI-9014296 https://reactome.org/PathwayBrowser/#/R-DDI-9014296 RAC2 GEFs activate RAC2 IEA Dictyostelium discoideum 37565 R-DDI-9014420 https://reactome.org/PathwayBrowser/#/R-DDI-9014420 RAC2 translocates to the phagocytic vesicle membrane IEA Dictyostelium discoideum 37565 R-DDI-9014433 https://reactome.org/PathwayBrowser/#/R-DDI-9014433 RHOG GEFs activate RHOG IEA Dictyostelium discoideum 37565 R-DDI-9014449 https://reactome.org/PathwayBrowser/#/R-DDI-9014449 RHOG binds effectors at the plasma membrane IEA Dictyostelium discoideum 37565 R-DDI-9014454 https://reactome.org/PathwayBrowser/#/R-DDI-9014454 RHOG translocates to the ER membrane IEA Dictyostelium discoideum 37565 R-DDI-9017488 https://reactome.org/PathwayBrowser/#/R-DDI-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Dictyostelium discoideum 37565 R-DDI-9017491 https://reactome.org/PathwayBrowser/#/R-DDI-9017491 RHOJ GEFs activate RHOJ IEA Dictyostelium discoideum 37565 R-DDI-9018745 https://reactome.org/PathwayBrowser/#/R-DDI-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Dictyostelium discoideum 37565 R-DDI-9018746 https://reactome.org/PathwayBrowser/#/R-DDI-9018746 RHOQ binds effectors at the plasma membrane IEA Dictyostelium discoideum 37565 R-DDI-9018747 https://reactome.org/PathwayBrowser/#/R-DDI-9018747 RHOQ GEFs activate RHOQ IEA Dictyostelium discoideum 37565 R-DDI-9018754 https://reactome.org/PathwayBrowser/#/R-DDI-9018754 GDIs bind RHOH IEA Dictyostelium discoideum 37565 R-DDI-9018756 https://reactome.org/PathwayBrowser/#/R-DDI-9018756 RHOH binds GTP IEA Dictyostelium discoideum 37565 R-DDI-9018758 https://reactome.org/PathwayBrowser/#/R-DDI-9018758 RHOH binds effectors at the plasma membrane IEA Dictyostelium discoideum 37565 R-DDI-9018766 https://reactome.org/PathwayBrowser/#/R-DDI-9018766 RHOU binds effectors at the plasma membrane IEA Dictyostelium discoideum 37565 R-DDI-9018768 https://reactome.org/PathwayBrowser/#/R-DDI-9018768 RHOU auto-activates IEA Dictyostelium discoideum 37565 R-DDI-9018774 https://reactome.org/PathwayBrowser/#/R-DDI-9018774 RHOBTB1 binds GTP IEA Dictyostelium discoideum 37565 R-DDI-9018778 https://reactome.org/PathwayBrowser/#/R-DDI-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Dictyostelium discoideum 37565 R-DDI-9018787 https://reactome.org/PathwayBrowser/#/R-DDI-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Dictyostelium discoideum 37565 R-DDI-9018794 https://reactome.org/PathwayBrowser/#/R-DDI-9018794 RHOV binds effectors at the plasma membrane IEA Dictyostelium discoideum 37565 R-DDI-9018798 https://reactome.org/PathwayBrowser/#/R-DDI-9018798 RHOV binds GTP IEA Dictyostelium discoideum 37565 R-DDI-9018804 https://reactome.org/PathwayBrowser/#/R-DDI-9018804 RAC3 GEFs activate RAC3 IEA Dictyostelium discoideum 37565 R-DDI-9018806 https://reactome.org/PathwayBrowser/#/R-DDI-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Dictyostelium discoideum 37565 R-DDI-9018808 https://reactome.org/PathwayBrowser/#/R-DDI-9018808 RAC3 binds effectors at the plasma membrane IEA Dictyostelium discoideum 37565 R-DDI-9018814 https://reactome.org/PathwayBrowser/#/R-DDI-9018814 RHOT1 hydrolyzes GTP IEA Dictyostelium discoideum 37565 R-DDI-9018815 https://reactome.org/PathwayBrowser/#/R-DDI-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Dictyostelium discoideum 37565 R-DDI-9018824 https://reactome.org/PathwayBrowser/#/R-DDI-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Dictyostelium discoideum 37565 R-DDI-9018826 https://reactome.org/PathwayBrowser/#/R-DDI-9018826 RHOT2 hydrolyzes GTP IEA Dictyostelium discoideum 37565 R-DDI-9018836 https://reactome.org/PathwayBrowser/#/R-DDI-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Dictyostelium discoideum 37565 R-DDI-939265 https://reactome.org/PathwayBrowser/#/R-DDI-939265 Activation of Rap1 by membrane-associated GEFs IEA Dictyostelium discoideum 37565 R-DDI-947535 https://reactome.org/PathwayBrowser/#/R-DDI-947535 Cyclisation of GTP to precursor Z IEA Dictyostelium discoideum 37565 R-DDI-9624845 https://reactome.org/PathwayBrowser/#/R-DDI-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Dictyostelium discoideum 37565 R-DDI-9624876 https://reactome.org/PathwayBrowser/#/R-DDI-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Dictyostelium discoideum 37565 R-DDI-9639286 https://reactome.org/PathwayBrowser/#/R-DDI-9639286 RRAGC,D exchanges GTP for GDP IEA Dictyostelium discoideum 37565 R-DDI-9640167 https://reactome.org/PathwayBrowser/#/R-DDI-9640167 RRAGA,B exchanges GDP for GTP IEA Dictyostelium discoideum 37565 R-DDI-9640195 https://reactome.org/PathwayBrowser/#/R-DDI-9640195 RRAGA,B hydrolyzes GTP IEA Dictyostelium discoideum 37565 R-DDI-9645598 https://reactome.org/PathwayBrowser/#/R-DDI-9645598 RRAGC,D hydrolyzes GTP IEA Dictyostelium discoideum 37565 R-DDI-9645608 https://reactome.org/PathwayBrowser/#/R-DDI-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Dictyostelium discoideum 37565 R-DDI-9646468 https://reactome.org/PathwayBrowser/#/R-DDI-9646468 mTORC1 binds RHEB:GTP IEA Dictyostelium discoideum 37565 R-DDI-9646685 https://reactome.org/PathwayBrowser/#/R-DDI-9646685 Aggresome dissociates from dynein and microtubule IEA Dictyostelium discoideum 37565 R-DDI-9668419 https://reactome.org/PathwayBrowser/#/R-DDI-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Dictyostelium discoideum 37565 R-DDI-9691168 https://reactome.org/PathwayBrowser/#/R-DDI-9691168 RAC1 translocates to the endoplasmic reticulum membrane IEA Dictyostelium discoideum 37565 R-DDI-9692800 https://reactome.org/PathwayBrowser/#/R-DDI-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Dictyostelium discoideum 37565 R-DDI-9714477 https://reactome.org/PathwayBrowser/#/R-DDI-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Dictyostelium discoideum 37565 R-DDI-9714480 https://reactome.org/PathwayBrowser/#/R-DDI-9714480 RAC2 translocates to the mitochondrial membrane IEA Dictyostelium discoideum 37565 R-DDI-9714483 https://reactome.org/PathwayBrowser/#/R-DDI-9714483 RAC2 translocates to the ER membrane IEA Dictyostelium discoideum 37565 R-DDI-9714694 https://reactome.org/PathwayBrowser/#/R-DDI-9714694 RAC3 translocates to the endoplasmic reticulum membrane IEA Dictyostelium discoideum 37565 R-DME-1008248 https://reactome.org/PathwayBrowser/#/R-DME-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Drosophila melanogaster 37565 R-DME-110491 https://reactome.org/PathwayBrowser/#/R-DME-110491 DRheb is inhibited by the TSC1/2 complex TAS Drosophila melanogaster 37565 R-DME-111524 https://reactome.org/PathwayBrowser/#/R-DME-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Drosophila melanogaster 37565 R-DME-111879 https://reactome.org/PathwayBrowser/#/R-DME-111879 PIP2 hydrolysis IEA Drosophila melanogaster 37565 R-DME-112037 https://reactome.org/PathwayBrowser/#/R-DME-112037 Inactivation of PLC beta IEA Drosophila melanogaster 37565 R-DME-114544 https://reactome.org/PathwayBrowser/#/R-DME-114544 p115-RhoGEF activation of RHOA IEA Drosophila melanogaster 37565 R-DME-114548 https://reactome.org/PathwayBrowser/#/R-DME-114548 G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) IEA Drosophila melanogaster 37565 R-DME-114688 https://reactome.org/PathwayBrowser/#/R-DME-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Drosophila melanogaster 37565 R-DME-1250383 https://reactome.org/PathwayBrowser/#/R-DME-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Drosophila melanogaster 37565 R-DME-1306972 https://reactome.org/PathwayBrowser/#/R-DME-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Drosophila melanogaster 37565 R-DME-1433415 https://reactome.org/PathwayBrowser/#/R-DME-1433415 Activation of RAC1 IEA Drosophila melanogaster 37565 R-DME-1433471 https://reactome.org/PathwayBrowser/#/R-DME-1433471 Activation of RAS by p-KIT bound SOS1 IEA Drosophila melanogaster 37565 R-DME-1474146 https://reactome.org/PathwayBrowser/#/R-DME-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Drosophila melanogaster 37565 R-DME-156823 https://reactome.org/PathwayBrowser/#/R-DME-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Drosophila melanogaster 37565 R-DME-156913 https://reactome.org/PathwayBrowser/#/R-DME-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Drosophila melanogaster 37565 R-DME-156930 https://reactome.org/PathwayBrowser/#/R-DME-156930 GTP-binding activates eEF2 IEA Drosophila melanogaster 37565 R-DME-157849 https://reactome.org/PathwayBrowser/#/R-DME-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Drosophila melanogaster 37565 R-DME-165129 https://reactome.org/PathwayBrowser/#/R-DME-165129 GDP is exchanged for GTP on DRheb TAS Drosophila melanogaster 37565 R-DME-165131 https://reactome.org/PathwayBrowser/#/R-DME-165131 GEF dissociates from DRheb-GTP TAS Drosophila melanogaster 37565 R-DME-165195 https://reactome.org/PathwayBrowser/#/R-DME-165195 GTP loading by Rheb IEA Drosophila melanogaster 37565 R-DME-165680 https://reactome.org/PathwayBrowser/#/R-DME-165680 Formation of active mTORC1 complex IEA Drosophila melanogaster 37565 R-DME-165692 https://reactome.org/PathwayBrowser/#/R-DME-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Drosophila melanogaster 37565 R-DME-165718 https://reactome.org/PathwayBrowser/#/R-DME-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Drosophila melanogaster 37565 R-DME-167415 https://reactome.org/PathwayBrowser/#/R-DME-167415 G-protein alpha subunit is inactivated IEA Drosophila melanogaster 37565 R-DME-167429 https://reactome.org/PathwayBrowser/#/R-DME-167429 The receptor:G-protein complex binds GTP IEA Drosophila melanogaster 37565 R-DME-170026 https://reactome.org/PathwayBrowser/#/R-DME-170026 Protons are translocated from the intermembrane space to the matrix IEA Drosophila melanogaster 37565 R-DME-170666 https://reactome.org/PathwayBrowser/#/R-DME-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Drosophila melanogaster 37565 R-DME-170671 https://reactome.org/PathwayBrowser/#/R-DME-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Drosophila melanogaster 37565 R-DME-170672 https://reactome.org/PathwayBrowser/#/R-DME-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Drosophila melanogaster 37565 R-DME-170676 https://reactome.org/PathwayBrowser/#/R-DME-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Drosophila melanogaster 37565 R-DME-170685 https://reactome.org/PathwayBrowser/#/R-DME-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Drosophila melanogaster 37565 R-DME-170686 https://reactome.org/PathwayBrowser/#/R-DME-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Drosophila melanogaster 37565 R-DME-170986 https://reactome.org/PathwayBrowser/#/R-DME-170986 Ral-GDS binds to Ras-GTP IEA Drosophila melanogaster 37565 R-DME-177938 https://reactome.org/PathwayBrowser/#/R-DME-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Drosophila melanogaster 37565 R-DME-177945 https://reactome.org/PathwayBrowser/#/R-DME-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Drosophila melanogaster 37565 R-DME-183002 https://reactome.org/PathwayBrowser/#/R-DME-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Drosophila melanogaster 37565 R-DME-183084 https://reactome.org/PathwayBrowser/#/R-DME-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Drosophila melanogaster 37565 R-DME-183094 https://reactome.org/PathwayBrowser/#/R-DME-183094 CDC42:GTP binds CBL:Beta-Pix IEA Drosophila melanogaster 37565 R-DME-186834 https://reactome.org/PathwayBrowser/#/R-DME-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Drosophila melanogaster 37565 R-DME-194518 https://reactome.org/PathwayBrowser/#/R-DME-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Drosophila melanogaster 37565 R-DME-2029454 https://reactome.org/PathwayBrowser/#/R-DME-2029454 Autophosphorylation of PAK1 IEA Drosophila melanogaster 37565 R-DME-2029456 https://reactome.org/PathwayBrowser/#/R-DME-2029456 RAC1 and CDC42 activate PAK1 IEA Drosophila melanogaster 37565 R-DME-2029465 https://reactome.org/PathwayBrowser/#/R-DME-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Drosophila melanogaster 37565 R-DME-2029466 https://reactome.org/PathwayBrowser/#/R-DME-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Drosophila melanogaster 37565 R-DME-2029469 https://reactome.org/PathwayBrowser/#/R-DME-2029469 p-ERK phosphorylates WAVEs and ABI IEA Drosophila melanogaster 37565 R-DME-203977 https://reactome.org/PathwayBrowser/#/R-DME-203977 SAR1 Activation And Membrane Binding IEA Drosophila melanogaster 37565 R-DME-203979 https://reactome.org/PathwayBrowser/#/R-DME-203979 Coat Assembly IEA Drosophila melanogaster 37565 R-DME-204008 https://reactome.org/PathwayBrowser/#/R-DME-204008 SEC31:SEC13 and v-SNARE recruitment IEA Drosophila melanogaster 37565 R-DME-205039 https://reactome.org/PathwayBrowser/#/R-DME-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Drosophila melanogaster 37565 R-DME-205136 https://reactome.org/PathwayBrowser/#/R-DME-205136 GTP-bound RAC contributes to JNK activation IEA Drosophila melanogaster 37565 R-DME-2065539 https://reactome.org/PathwayBrowser/#/R-DME-2065539 SREBP1A,1C,2:Importin beta-1 dissociates IEA Drosophila melanogaster 37565 R-DME-2130194 https://reactome.org/PathwayBrowser/#/R-DME-2130194 ABL phosphorylates WAVEs IEA Drosophila melanogaster 37565 R-DME-2179407 https://reactome.org/PathwayBrowser/#/R-DME-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Drosophila melanogaster 37565 R-DME-2197690 https://reactome.org/PathwayBrowser/#/R-DME-2197690 Detachment of WASP/WAVE IEA Drosophila melanogaster 37565 R-DME-2214351 https://reactome.org/PathwayBrowser/#/R-DME-2214351 PLK1 phosphorylates GORASP1 IEA Drosophila melanogaster 37565 R-DME-2422927 https://reactome.org/PathwayBrowser/#/R-DME-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Drosophila melanogaster 37565 R-DME-2424476 https://reactome.org/PathwayBrowser/#/R-DME-2424476 Activation of RAC1 by VAV2/3 IEA Drosophila melanogaster 37565 R-DME-2424477 https://reactome.org/PathwayBrowser/#/R-DME-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Drosophila melanogaster 37565 R-DME-2562526 https://reactome.org/PathwayBrowser/#/R-DME-2562526 PLK1 phosphorylates OPTN IEA Drosophila melanogaster 37565 R-DME-2730840 https://reactome.org/PathwayBrowser/#/R-DME-2730840 Activation of RAC1 by VAV IEA Drosophila melanogaster 37565 R-DME-2730856 https://reactome.org/PathwayBrowser/#/R-DME-2730856 Autophosphorylation of PAK IEA Drosophila melanogaster 37565 R-DME-2730889 https://reactome.org/PathwayBrowser/#/R-DME-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Drosophila melanogaster 37565 R-DME-350362 https://reactome.org/PathwayBrowser/#/R-DME-350362 ROK phosphorylates MBS TAS Drosophila melanogaster 37565 R-DME-350385 https://reactome.org/PathwayBrowser/#/R-DME-350385 DSH binds to RAC1:GTP IEA Drosophila melanogaster 37565 R-DME-350388 https://reactome.org/PathwayBrowser/#/R-DME-350388 ROK binds to activated RHO1:GTP TAS Drosophila melanogaster 37565 R-DME-350391 https://reactome.org/PathwayBrowser/#/R-DME-350391 RHO1:GTP binds to activated DAAM IEA Drosophila melanogaster 37565 R-DME-350444 https://reactome.org/PathwayBrowser/#/R-DME-350444 ROK phosphorylates SQH TAS Drosophila melanogaster 37565 R-DME-350450 https://reactome.org/PathwayBrowser/#/R-DME-350450 RHO1:GTP complex dissociates from RHOGEF2 TAS Drosophila melanogaster 37565 R-DME-350453 https://reactome.org/PathwayBrowser/#/R-DME-350453 RHOGAPP190 binds to RHO1:GTP complex at the plasma membrane TAS Drosophila melanogaster 37565 R-DME-350458 https://reactome.org/PathwayBrowser/#/R-DME-350458 RHOGAPP190 activates GTP hydrolysis by RHO1:GTP TAS Drosophila melanogaster 37565 R-DME-350477 https://reactome.org/PathwayBrowser/#/R-DME-350477 RHOGEF2 stimulates nucleotide exchange of RHO1:GDP complex TAS Drosophila melanogaster 37565 R-DME-350769 https://reactome.org/PathwayBrowser/#/R-DME-350769 trans-Golgi Network Coat Activation IEA Drosophila melanogaster 37565 R-DME-354060 https://reactome.org/PathwayBrowser/#/R-DME-354060 Translocation of RIAM to plasma membrane IEA Drosophila melanogaster 37565 R-DME-354077 https://reactome.org/PathwayBrowser/#/R-DME-354077 Integrin alphaIIb beta3 activation IEA Drosophila melanogaster 37565 R-DME-354097 https://reactome.org/PathwayBrowser/#/R-DME-354097 Activation of Talin IEA Drosophila melanogaster 37565 R-DME-354149 https://reactome.org/PathwayBrowser/#/R-DME-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Drosophila melanogaster 37565 R-DME-372819 https://reactome.org/PathwayBrowser/#/R-DME-372819 PCK2 phosphorylates OA to yield PEP IEA Drosophila melanogaster 37565 R-DME-377186 https://reactome.org/PathwayBrowser/#/R-DME-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Drosophila melanogaster 37565 R-DME-377640 https://reactome.org/PathwayBrowser/#/R-DME-377640 Autophosphorylation of SRC IEA Drosophila melanogaster 37565 R-DME-377641 https://reactome.org/PathwayBrowser/#/R-DME-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Drosophila melanogaster 37565 R-DME-377643 https://reactome.org/PathwayBrowser/#/R-DME-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Drosophila melanogaster 37565 R-DME-377644 https://reactome.org/PathwayBrowser/#/R-DME-377644 Release of CSK from SRC IEA Drosophila melanogaster 37565 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 37565 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 37565 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 37565 R-DME-380979 https://reactome.org/PathwayBrowser/#/R-DME-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Drosophila melanogaster 37565 R-DME-381727 https://reactome.org/PathwayBrowser/#/R-DME-381727 RAP1A exchanges GDP for GTP IEA Drosophila melanogaster 37565 R-DME-3858475 https://reactome.org/PathwayBrowser/#/R-DME-3858475 ppDVL recruits RAC IEA Drosophila melanogaster 37565 R-DME-3858495 https://reactome.org/PathwayBrowser/#/R-DME-3858495 DAAM1 recruits GTP-bound RHOA IEA Drosophila melanogaster 37565 R-DME-389788 https://reactome.org/PathwayBrowser/#/R-DME-389788 Activation of PAKs by RAC1 and CDC42 IEA Drosophila melanogaster 37565 R-DME-392054 https://reactome.org/PathwayBrowser/#/R-DME-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Drosophila melanogaster 37565 R-DME-392195 https://reactome.org/PathwayBrowser/#/R-DME-392195 Gi activation by P2Y purinoceptor 12 IEA Drosophila melanogaster 37565 R-DME-392513 https://reactome.org/PathwayBrowser/#/R-DME-392513 Rap1 signal termination by Rap1GAPs IEA Drosophila melanogaster 37565 R-DME-392835 https://reactome.org/PathwayBrowser/#/R-DME-392835 Rap1 sequesters Raf1 to inhibit ERK cascade IEA Drosophila melanogaster 37565 R-DME-3928576 https://reactome.org/PathwayBrowser/#/R-DME-3928576 RHOA:GTP binds ROCK, activating it IEA Drosophila melanogaster 37565 R-DME-3928592 https://reactome.org/PathwayBrowser/#/R-DME-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Drosophila melanogaster 37565 R-DME-3928595 https://reactome.org/PathwayBrowser/#/R-DME-3928595 N-WASP binds ARP2/3 and G-actin IEA Drosophila melanogaster 37565 R-DME-3928601 https://reactome.org/PathwayBrowser/#/R-DME-3928601 CDC42 and PIP2 bind WASL, activating it IEA Drosophila melanogaster 37565 R-DME-3928612 https://reactome.org/PathwayBrowser/#/R-DME-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 37565 R-DME-3928619 https://reactome.org/PathwayBrowser/#/R-DME-3928619 PAK1 binds RAC1:GTP IEA Drosophila melanogaster 37565 R-DME-3928620 https://reactome.org/PathwayBrowser/#/R-DME-3928620 PAK1 autophosphorylates IEA Drosophila melanogaster 37565 R-DME-3928625 https://reactome.org/PathwayBrowser/#/R-DME-3928625 PAKs autophosphorylate IEA Drosophila melanogaster 37565 R-DME-3928628 https://reactome.org/PathwayBrowser/#/R-DME-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 37565 R-DME-3928633 https://reactome.org/PathwayBrowser/#/R-DME-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Drosophila melanogaster 37565 R-DME-3928640 https://reactome.org/PathwayBrowser/#/R-DME-3928640 PAKs phosphorylate MLC IEA Drosophila melanogaster 37565 R-DME-3928641 https://reactome.org/PathwayBrowser/#/R-DME-3928641 PAK binds RAC and bPIX IEA Drosophila melanogaster 37565 R-DME-3928642 https://reactome.org/PathwayBrowser/#/R-DME-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 37565 R-DME-3928647 https://reactome.org/PathwayBrowser/#/R-DME-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Drosophila melanogaster 37565 R-DME-3928651 https://reactome.org/PathwayBrowser/#/R-DME-3928651 NGEF exchanges GTP for GDP on RHOA IEA Drosophila melanogaster 37565 R-DME-392870 https://reactome.org/PathwayBrowser/#/R-DME-392870 Gs activation by prostacyclin receptor IEA Drosophila melanogaster 37565 R-DME-3965444 https://reactome.org/PathwayBrowser/#/R-DME-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-3965447 https://reactome.org/PathwayBrowser/#/R-DME-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Drosophila melanogaster 37565 R-DME-398184 https://reactome.org/PathwayBrowser/#/R-DME-398184 LARG activation by G alpha 12/13 IEA Drosophila melanogaster 37565 R-DME-398185 https://reactome.org/PathwayBrowser/#/R-DME-398185 LARG binds plexin B1 IEA Drosophila melanogaster 37565 R-DME-399930 https://reactome.org/PathwayBrowser/#/R-DME-399930 Activation of PAK by Rac1 IEA Drosophila melanogaster 37565 R-DME-399939 https://reactome.org/PathwayBrowser/#/R-DME-399939 Autophosphorylation of PAK IEA Drosophila melanogaster 37565 R-DME-399952 https://reactome.org/PathwayBrowser/#/R-DME-399952 Phosphorylation of LIMK-1 by PAK IEA Drosophila melanogaster 37565 R-DME-399998 https://reactome.org/PathwayBrowser/#/R-DME-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Drosophila melanogaster 37565 R-DME-400037 https://reactome.org/PathwayBrowser/#/R-DME-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Drosophila melanogaster 37565 R-DME-400092 https://reactome.org/PathwayBrowser/#/R-DME-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Drosophila melanogaster 37565 R-DME-400586 https://reactome.org/PathwayBrowser/#/R-DME-400586 G alpha (q) binds to Trio family RhoGEFs IEA Drosophila melanogaster 37565 R-DME-4093331 https://reactome.org/PathwayBrowser/#/R-DME-4093331 Ras:GTP binds p120-RasGAP IEA Drosophila melanogaster 37565 R-DME-4093336 https://reactome.org/PathwayBrowser/#/R-DME-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 37565 R-DME-4093339 https://reactome.org/PathwayBrowser/#/R-DME-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Drosophila melanogaster 37565 R-DME-416516 https://reactome.org/PathwayBrowser/#/R-DME-416516 GRK2 sequesters activated Gq IEA Drosophila melanogaster 37565 R-DME-416588 https://reactome.org/PathwayBrowser/#/R-DME-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Drosophila melanogaster 37565 R-DME-418574 https://reactome.org/PathwayBrowser/#/R-DME-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Drosophila melanogaster 37565 R-DME-418582 https://reactome.org/PathwayBrowser/#/R-DME-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Drosophila melanogaster 37565 R-DME-418850 https://reactome.org/PathwayBrowser/#/R-DME-418850 Activation of Cdc42 IEA Drosophila melanogaster 37565 R-DME-418856 https://reactome.org/PathwayBrowser/#/R-DME-418856 Activation of Rac1 IEA Drosophila melanogaster 37565 R-DME-419049 https://reactome.org/PathwayBrowser/#/R-DME-419049 ROCK activation by RHO IEA Drosophila melanogaster 37565 R-DME-419166 https://reactome.org/PathwayBrowser/#/R-DME-419166 GEFs activate RhoA,B,C IEA Drosophila melanogaster 37565 R-DME-421831 https://reactome.org/PathwayBrowser/#/R-DME-421831 trans-Golgi Network Coat Assembly IEA Drosophila melanogaster 37565 R-DME-421833 https://reactome.org/PathwayBrowser/#/R-DME-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture IEA Drosophila melanogaster 37565 R-DME-421835 https://reactome.org/PathwayBrowser/#/R-DME-421835 trans-Golgi Network Vesicle Scission IEA Drosophila melanogaster 37565 R-DME-428520 https://reactome.org/PathwayBrowser/#/R-DME-428520 Inactivation of Rac1 TAS Drosophila melanogaster 37565 R-DME-428523 https://reactome.org/PathwayBrowser/#/R-DME-428523 Activation of Rac by Sos TAS Drosophila melanogaster 37565 R-DME-428750 https://reactome.org/PathwayBrowser/#/R-DME-428750 Gq activation by TP receptor IEA Drosophila melanogaster 37565 R-DME-428752 https://reactome.org/PathwayBrowser/#/R-DME-428752 Dissociation of the TP:Gq complex IEA Drosophila melanogaster 37565 R-DME-428917 https://reactome.org/PathwayBrowser/#/R-DME-428917 G13 activation by TP receptor IEA Drosophila melanogaster 37565 R-DME-428918 https://reactome.org/PathwayBrowser/#/R-DME-428918 Dissociation of the TP:G13 complex IEA Drosophila melanogaster 37565 R-DME-428941 https://reactome.org/PathwayBrowser/#/R-DME-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Drosophila melanogaster 37565 R-DME-429415 https://reactome.org/PathwayBrowser/#/R-DME-429415 SYK binds to integrin alphaIIb beta3 IEA Drosophila melanogaster 37565 R-DME-429441 https://reactome.org/PathwayBrowser/#/R-DME-429441 SYK activation by SRC IEA Drosophila melanogaster 37565 R-DME-432096 https://reactome.org/PathwayBrowser/#/R-DME-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Drosophila melanogaster 37565 R-DME-432535 https://reactome.org/PathwayBrowser/#/R-DME-432535 TIM is phosphorylated by CK2 TAS Drosophila melanogaster 37565 R-DME-432590 https://reactome.org/PathwayBrowser/#/R-DME-432590 Phosphorylated PER is phosphorylated by CK2 TAS Drosophila melanogaster 37565 R-DME-432706 https://reactome.org/PathwayBrowser/#/R-DME-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Drosophila melanogaster 37565 R-DME-432707 https://reactome.org/PathwayBrowser/#/R-DME-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Drosophila melanogaster 37565 R-DME-442273 https://reactome.org/PathwayBrowser/#/R-DME-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Drosophila melanogaster 37565 R-DME-442291 https://reactome.org/PathwayBrowser/#/R-DME-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Drosophila melanogaster 37565 R-DME-442314 https://reactome.org/PathwayBrowser/#/R-DME-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Drosophila melanogaster 37565 R-DME-443905 https://reactome.org/PathwayBrowser/#/R-DME-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Drosophila melanogaster 37565 R-DME-443910 https://reactome.org/PathwayBrowser/#/R-DME-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Drosophila melanogaster 37565 R-DME-445064 https://reactome.org/PathwayBrowser/#/R-DME-445064 Activation of Rac1 by VAV2 IEA Drosophila melanogaster 37565 R-DME-445072 https://reactome.org/PathwayBrowser/#/R-DME-445072 Interaction of PAK1 with Rac1-GTP IEA Drosophila melanogaster 37565 R-DME-447074 https://reactome.org/PathwayBrowser/#/R-DME-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Drosophila melanogaster 37565 R-DME-448958 https://reactome.org/PathwayBrowser/#/R-DME-448958 Nuclear translocation of p38 MAPK IEA Drosophila melanogaster 37565 R-DME-450723 https://reactome.org/PathwayBrowser/#/R-DME-450723 RAC1:GTP and MSN activate HEP TAS Drosophila melanogaster 37565 R-DME-450770 https://reactome.org/PathwayBrowser/#/R-DME-450770 MWH binds to RHO1:GTP and is activated TAS Drosophila melanogaster 37565 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 37565 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 37565 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 37565 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 37565 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 37565 R-DME-5218804 https://reactome.org/PathwayBrowser/#/R-DME-5218804 p38 MAPK activation by VEGFR IEA Drosophila melanogaster 37565 R-DME-5218812 https://reactome.org/PathwayBrowser/#/R-DME-5218812 FYN phosphorylates PAK2 IEA Drosophila melanogaster 37565 R-DME-5218814 https://reactome.org/PathwayBrowser/#/R-DME-5218814 PAK2 autophorylates IEA Drosophila melanogaster 37565 R-DME-5218832 https://reactome.org/PathwayBrowser/#/R-DME-5218832 CDC42:GTP binds PAK2 IEA Drosophila melanogaster 37565 R-DME-5218839 https://reactome.org/PathwayBrowser/#/R-DME-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Drosophila melanogaster 37565 R-DME-5218845 https://reactome.org/PathwayBrowser/#/R-DME-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Drosophila melanogaster 37565 R-DME-5218850 https://reactome.org/PathwayBrowser/#/R-DME-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 37565 R-DME-5228992 https://reactome.org/PathwayBrowser/#/R-DME-5228992 ROCK1,ROCK2 are activated IEA Drosophila melanogaster 37565 R-DME-5357445 https://reactome.org/PathwayBrowser/#/R-DME-5357445 PAK1-3 dimer disassociates IEA Drosophila melanogaster 37565 R-DME-5357472 https://reactome.org/PathwayBrowser/#/R-DME-5357472 PAK1-3 autophosphorylates IEA Drosophila melanogaster 37565 R-DME-5357483 https://reactome.org/PathwayBrowser/#/R-DME-5357483 RAC1 binds PAK1-3 IEA Drosophila melanogaster 37565 R-DME-5419261 https://reactome.org/PathwayBrowser/#/R-DME-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Drosophila melanogaster 37565 R-DME-5419264 https://reactome.org/PathwayBrowser/#/R-DME-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Drosophila melanogaster 37565 R-DME-5419271 https://reactome.org/PathwayBrowser/#/R-DME-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Drosophila melanogaster 37565 R-DME-5419273 https://reactome.org/PathwayBrowser/#/R-DME-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Drosophila melanogaster 37565 R-DME-555065 https://reactome.org/PathwayBrowser/#/R-DME-555065 Formation of clathrin coated vesicle IEA Drosophila melanogaster 37565 R-DME-5578744 https://reactome.org/PathwayBrowser/#/R-DME-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Drosophila melanogaster 37565 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 37565 R-DME-5620914 https://reactome.org/PathwayBrowser/#/R-DME-5620914 ARF4:GTP binds VxPx-motifs of membrane proteins IEA Drosophila melanogaster 37565 R-DME-5620921 https://reactome.org/PathwayBrowser/#/R-DME-5620921 ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex IEA Drosophila melanogaster 37565 R-DME-5623508 https://reactome.org/PathwayBrowser/#/R-DME-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Drosophila melanogaster 37565 R-DME-5623513 https://reactome.org/PathwayBrowser/#/R-DME-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Drosophila melanogaster 37565 R-DME-5623521 https://reactome.org/PathwayBrowser/#/R-DME-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Drosophila melanogaster 37565 R-DME-5623524 https://reactome.org/PathwayBrowser/#/R-DME-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Drosophila melanogaster 37565 R-DME-5623525 https://reactome.org/PathwayBrowser/#/R-DME-5623525 Cargo-carrying vesicles bud from the TGN IEA Drosophila melanogaster 37565 R-DME-5623527 https://reactome.org/PathwayBrowser/#/R-DME-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Drosophila melanogaster 37565 R-DME-5623622 https://reactome.org/PathwayBrowser/#/R-DME-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Drosophila melanogaster 37565 R-DME-5623632 https://reactome.org/PathwayBrowser/#/R-DME-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Drosophila melanogaster 37565 R-DME-5623667 https://reactome.org/PathwayBrowser/#/R-DME-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Drosophila melanogaster 37565 R-DME-5624486 https://reactome.org/PathwayBrowser/#/R-DME-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Drosophila melanogaster 37565 R-DME-5624492 https://reactome.org/PathwayBrowser/#/R-DME-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Drosophila melanogaster 37565 R-DME-5624494 https://reactome.org/PathwayBrowser/#/R-DME-5624494 RAF1 binds p21 RAS:GTP IEA Drosophila melanogaster 37565 R-DME-5627775 https://reactome.org/PathwayBrowser/#/R-DME-5627775 Autophosphorylation of PAK1,2,3 IEA Drosophila melanogaster 37565 R-DME-5653957 https://reactome.org/PathwayBrowser/#/R-DME-5653957 Rag dimer formation IEA Drosophila melanogaster 37565 R-DME-5653968 https://reactome.org/PathwayBrowser/#/R-DME-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Drosophila melanogaster 37565 R-DME-5653974 https://reactome.org/PathwayBrowser/#/R-DME-5653974 Ragulator binds Rag dimers IEA Drosophila melanogaster 37565 R-DME-5654392 https://reactome.org/PathwayBrowser/#/R-DME-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-5654402 https://reactome.org/PathwayBrowser/#/R-DME-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-5654413 https://reactome.org/PathwayBrowser/#/R-DME-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-5654426 https://reactome.org/PathwayBrowser/#/R-DME-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-5654600 https://reactome.org/PathwayBrowser/#/R-DME-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-5654618 https://reactome.org/PathwayBrowser/#/R-DME-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-5654647 https://reactome.org/PathwayBrowser/#/R-DME-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-5654663 https://reactome.org/PathwayBrowser/#/R-DME-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-5658231 https://reactome.org/PathwayBrowser/#/R-DME-5658231 RAS GAPs stimulate RAS GTPase activity IEA Drosophila melanogaster 37565 R-DME-5658435 https://reactome.org/PathwayBrowser/#/R-DME-5658435 RAS GAPs bind RAS:GTP IEA Drosophila melanogaster 37565 R-DME-5665727 https://reactome.org/PathwayBrowser/#/R-DME-5665727 FMNL2 binds CDC42:GTP IEA Drosophila melanogaster 37565 R-DME-5665989 https://reactome.org/PathwayBrowser/#/R-DME-5665989 DIAPH1 binds RHOA:GTP IEA Drosophila melanogaster 37565 R-DME-5666070 https://reactome.org/PathwayBrowser/#/R-DME-5666070 RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes IEA Drosophila melanogaster 37565 R-DME-5666088 https://reactome.org/PathwayBrowser/#/R-DME-5666088 RHOD:GTP recruits DAIPH2-3 to endosomes IEA Drosophila melanogaster 37565 R-DME-5666104 https://reactome.org/PathwayBrowser/#/R-DME-5666104 RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes IEA Drosophila melanogaster 37565 R-DME-5667008 https://reactome.org/PathwayBrowser/#/R-DME-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Drosophila melanogaster 37565 R-DME-5671970 https://reactome.org/PathwayBrowser/#/R-DME-5671970 Activated CIT binds KIF14 and PRC1 IEA Drosophila melanogaster 37565 R-DME-5671993 https://reactome.org/PathwayBrowser/#/R-DME-5671993 CIT-3 binds DLG4 IEA Drosophila melanogaster 37565 R-DME-5672010 https://reactome.org/PathwayBrowser/#/R-DME-5672010 Active MTORC1 phosphorylates ULK1 IEA Drosophila melanogaster 37565 R-DME-5672017 https://reactome.org/PathwayBrowser/#/R-DME-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Drosophila melanogaster 37565 R-DME-5672817 https://reactome.org/PathwayBrowser/#/R-DME-5672817 Active MTORC1 binds the ULK1 complex IEA Drosophila melanogaster 37565 R-DME-5672824 https://reactome.org/PathwayBrowser/#/R-DME-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Drosophila melanogaster 37565 R-DME-5672828 https://reactome.org/PathwayBrowser/#/R-DME-5672828 mTORC1 phosphorylates AKT1S1 IEA Drosophila melanogaster 37565 R-DME-5672843 https://reactome.org/PathwayBrowser/#/R-DME-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Drosophila melanogaster 37565 R-DME-5672950 https://reactome.org/PathwayBrowser/#/R-DME-5672950 "Activator" RAF:YWHAB dimer binds RAS:GTP IEA Drosophila melanogaster 37565 R-DME-5672965 https://reactome.org/PathwayBrowser/#/R-DME-5672965 RAS GEFs promote RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-5672966 https://reactome.org/PathwayBrowser/#/R-DME-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Drosophila melanogaster 37565 R-DME-5672969 https://reactome.org/PathwayBrowser/#/R-DME-5672969 Phosphorylation of RAF IEA Drosophila melanogaster 37565 R-DME-5672972 https://reactome.org/PathwayBrowser/#/R-DME-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Drosophila melanogaster 37565 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 37565 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 37565 R-DME-5672980 https://reactome.org/PathwayBrowser/#/R-DME-5672980 Dissociation of RAS:RAF complex IEA Drosophila melanogaster 37565 R-DME-5673768 https://reactome.org/PathwayBrowser/#/R-DME-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Drosophila melanogaster 37565 R-DME-5674018 https://reactome.org/PathwayBrowser/#/R-DME-5674018 BRAP binds RAS:GTP IEA Drosophila melanogaster 37565 R-DME-5674022 https://reactome.org/PathwayBrowser/#/R-DME-5674022 BRAP autoubiquitinates IEA Drosophila melanogaster 37565 R-DME-5675417 https://reactome.org/PathwayBrowser/#/R-DME-5675417 PEBP1 binds activated RAF1 IEA Drosophila melanogaster 37565 R-DME-5675431 https://reactome.org/PathwayBrowser/#/R-DME-5675431 PP2A dephosphorylates RAF1 IEA Drosophila melanogaster 37565 R-DME-5675433 https://reactome.org/PathwayBrowser/#/R-DME-5675433 PP5 dephosphorylates RAF1 S338 IEA Drosophila melanogaster 37565 R-DME-5675790 https://reactome.org/PathwayBrowser/#/R-DME-5675790 MTORC1 dissociates from ULK complex IEA Drosophila melanogaster 37565 R-DME-5694409 https://reactome.org/PathwayBrowser/#/R-DME-5694409 Nucleotide exchange on RAB1 IEA Drosophila melanogaster 37565 R-DME-5694418 https://reactome.org/PathwayBrowser/#/R-DME-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Drosophila melanogaster 37565 R-DME-5694522 https://reactome.org/PathwayBrowser/#/R-DME-5694522 Inner coat assembly and cargo binding IEA Drosophila melanogaster 37565 R-DME-5694527 https://reactome.org/PathwayBrowser/#/R-DME-5694527 Loss of SAR1B GTPase IEA Drosophila melanogaster 37565 R-DME-5696197 https://reactome.org/PathwayBrowser/#/R-DME-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Drosophila melanogaster 37565 R-DME-6785648 https://reactome.org/PathwayBrowser/#/R-DME-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Drosophila melanogaster 37565 R-DME-6788611 https://reactome.org/PathwayBrowser/#/R-DME-6788611 HYKK phosphorylates 5HLYS IEA Drosophila melanogaster 37565 R-DME-6800138 https://reactome.org/PathwayBrowser/#/R-DME-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Drosophila melanogaster 37565 R-DME-6807864 https://reactome.org/PathwayBrowser/#/R-DME-6807864 RAB1:GTP recruits GBF1 to the ERGIC IEA Drosophila melanogaster 37565 R-DME-6807866 https://reactome.org/PathwayBrowser/#/R-DME-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Drosophila melanogaster 37565 R-DME-6807868 https://reactome.org/PathwayBrowser/#/R-DME-6807868 GBF1 stimulates ARF nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-6807872 https://reactome.org/PathwayBrowser/#/R-DME-6807872 Active ARF recruits coatomer IEA Drosophila melanogaster 37565 R-DME-6807875 https://reactome.org/PathwayBrowser/#/R-DME-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Drosophila melanogaster 37565 R-DME-6807877 https://reactome.org/PathwayBrowser/#/R-DME-6807877 ARFGAPs stimulate ARF GTPase activity IEA Drosophila melanogaster 37565 R-DME-6809003 https://reactome.org/PathwayBrowser/#/R-DME-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Drosophila melanogaster 37565 R-DME-6809011 https://reactome.org/PathwayBrowser/#/R-DME-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Drosophila melanogaster 37565 R-DME-6811411 https://reactome.org/PathwayBrowser/#/R-DME-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Drosophila melanogaster 37565 R-DME-6811412 https://reactome.org/PathwayBrowser/#/R-DME-6811412 Active ARF recruits coatomer to the Golgi IEA Drosophila melanogaster 37565 R-DME-6811414 https://reactome.org/PathwayBrowser/#/R-DME-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Drosophila melanogaster 37565 R-DME-6811415 https://reactome.org/PathwayBrowser/#/R-DME-6811415 RAB:GTP recruits GBF1 to the Golgi membrane IEA Drosophila melanogaster 37565 R-DME-6811417 https://reactome.org/PathwayBrowser/#/R-DME-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Drosophila melanogaster 37565 R-DME-6811418 https://reactome.org/PathwayBrowser/#/R-DME-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Drosophila melanogaster 37565 R-DME-6811426 https://reactome.org/PathwayBrowser/#/R-DME-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Drosophila melanogaster 37565 R-DME-6811427 https://reactome.org/PathwayBrowser/#/R-DME-6811427 COPI vesicle uncoating at the ER IEA Drosophila melanogaster 37565 R-DME-6811429 https://reactome.org/PathwayBrowser/#/R-DME-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-6814086 https://reactome.org/PathwayBrowser/#/R-DME-6814086 ARFRP1 recruits ARL1 to the TGN IEA Drosophila melanogaster 37565 R-DME-6814088 https://reactome.org/PathwayBrowser/#/R-DME-6814088 SYS1 binds AcM-ARFRP1 IEA Drosophila melanogaster 37565 R-DME-6814091 https://reactome.org/PathwayBrowser/#/R-DME-6814091 ARL1 recruits TGN Golgin homodimers IEA Drosophila melanogaster 37565 R-DME-6814094 https://reactome.org/PathwayBrowser/#/R-DME-6814094 ARL1:GTP binds ARFIP2 IEA Drosophila melanogaster 37565 R-DME-6814096 https://reactome.org/PathwayBrowser/#/R-DME-6814096 ARL1:GTP binds SCOC IEA Drosophila melanogaster 37565 R-DME-6814549 https://reactome.org/PathwayBrowser/#/R-DME-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Drosophila melanogaster 37565 R-DME-6814559 https://reactome.org/PathwayBrowser/#/R-DME-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Drosophila melanogaster 37565 R-DME-6814670 https://reactome.org/PathwayBrowser/#/R-DME-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Drosophila melanogaster 37565 R-DME-6814674 https://reactome.org/PathwayBrowser/#/R-DME-6814674 Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins IEA Drosophila melanogaster 37565 R-DME-6814675 https://reactome.org/PathwayBrowser/#/R-DME-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Drosophila melanogaster 37565 R-DME-6814682 https://reactome.org/PathwayBrowser/#/R-DME-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Drosophila melanogaster 37565 R-DME-6814831 https://reactome.org/PathwayBrowser/#/R-DME-6814831 TBC1D20 binds RAB1:GTP IEA Drosophila melanogaster 37565 R-DME-6814833 https://reactome.org/PathwayBrowser/#/R-DME-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Drosophila melanogaster 37565 R-DME-70241 https://reactome.org/PathwayBrowser/#/R-DME-70241 PCK1 phosphorylates OA to yield PEP IEA Drosophila melanogaster 37565 R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Drosophila melanogaster 37565 R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Drosophila melanogaster 37565 R-DME-71775 https://reactome.org/PathwayBrowser/#/R-DME-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Drosophila melanogaster 37565 R-DME-72621 https://reactome.org/PathwayBrowser/#/R-DME-72621 Ribosomal scanning IEA Drosophila melanogaster 37565 R-DME-72663 https://reactome.org/PathwayBrowser/#/R-DME-72663 De novo formation of eIF2:GTP IEA Drosophila melanogaster 37565 R-DME-72669 https://reactome.org/PathwayBrowser/#/R-DME-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Drosophila melanogaster 37565 R-DME-72671 https://reactome.org/PathwayBrowser/#/R-DME-72671 eIF5B:GTP is hydrolyzed and released IEA Drosophila melanogaster 37565 R-DME-72672 https://reactome.org/PathwayBrowser/#/R-DME-72672 The 60S subunit joins the translation initiation complex IEA Drosophila melanogaster 37565 R-DME-72691 https://reactome.org/PathwayBrowser/#/R-DME-72691 Formation of the 43S pre-initiation complex IEA Drosophila melanogaster 37565 R-DME-72697 https://reactome.org/PathwayBrowser/#/R-DME-72697 Start codon recognition IEA Drosophila melanogaster 37565 R-DME-72722 https://reactome.org/PathwayBrowser/#/R-DME-72722 eIF2 activation IEA Drosophila melanogaster 37565 R-DME-74885 https://reactome.org/PathwayBrowser/#/R-DME-74885 GUCYs converts GTP to cGMP IEA Drosophila melanogaster 37565 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 37565 R-DME-749453 https://reactome.org/PathwayBrowser/#/R-DME-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Drosophila melanogaster 37565 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 37565 R-DME-751019 https://reactome.org/PathwayBrowser/#/R-DME-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Drosophila melanogaster 37565 R-DME-751029 https://reactome.org/PathwayBrowser/#/R-DME-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Drosophila melanogaster 37565 R-DME-77081 https://reactome.org/PathwayBrowser/#/R-DME-77081 Formation of the CE:GMP intermediate complex IEA Drosophila melanogaster 37565 R-DME-8847534 https://reactome.org/PathwayBrowser/#/R-DME-8847534 RAB43 hydrolyses GTP IEA Drosophila melanogaster 37565 R-DME-8847537 https://reactome.org/PathwayBrowser/#/R-DME-8847537 RAB43:GTP binds USP8NL IEA Drosophila melanogaster 37565 R-DME-8848618 https://reactome.org/PathwayBrowser/#/R-DME-8848618 Activation of RAC1 by the PXN:CRK complex IEA Drosophila melanogaster 37565 R-DME-8849082 https://reactome.org/PathwayBrowser/#/R-DME-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Drosophila melanogaster 37565 R-DME-8849085 https://reactome.org/PathwayBrowser/#/R-DME-8849085 ARHGAP35 binds RHOA:GTP IEA Drosophila melanogaster 37565 R-DME-8849348 https://reactome.org/PathwayBrowser/#/R-DME-8849348 RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo IEA Drosophila melanogaster 37565 R-DME-8849350 https://reactome.org/PathwayBrowser/#/R-DME-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Drosophila melanogaster 37565 R-DME-8849353 https://reactome.org/PathwayBrowser/#/R-DME-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Drosophila melanogaster 37565 R-DME-8849748 https://reactome.org/PathwayBrowser/#/R-DME-8849748 The COG complex binds RABs at the Golgi membrane IEA Drosophila melanogaster 37565 R-DME-8850041 https://reactome.org/PathwayBrowser/#/R-DME-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Drosophila melanogaster 37565 R-DME-8854173 https://reactome.org/PathwayBrowser/#/R-DME-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Drosophila melanogaster 37565 R-DME-8854182 https://reactome.org/PathwayBrowser/#/R-DME-8854182 TBC1D17 binds OPTN:RAB8A IEA Drosophila melanogaster 37565 R-DME-8854293 https://reactome.org/PathwayBrowser/#/R-DME-8854293 TBC1D10A (EPI64) binds ARF6:GTP IEA Drosophila melanogaster 37565 R-DME-8854303 https://reactome.org/PathwayBrowser/#/R-DME-8854303 TBC1D11 binds RAB6 IEA Drosophila melanogaster 37565 R-DME-8868236 https://reactome.org/PathwayBrowser/#/R-DME-8868236 BAR domain proteins recruit dynamin IEA Drosophila melanogaster 37565 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster 37565 R-DME-8868651 https://reactome.org/PathwayBrowser/#/R-DME-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Drosophila melanogaster 37565 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster 37565 R-DME-8875318 https://reactome.org/PathwayBrowser/#/R-DME-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Drosophila melanogaster 37565 R-DME-8875320 https://reactome.org/PathwayBrowser/#/R-DME-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Drosophila melanogaster 37565 R-DME-8876188 https://reactome.org/PathwayBrowser/#/R-DME-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Drosophila melanogaster 37565 R-DME-8876193 https://reactome.org/PathwayBrowser/#/R-DME-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Drosophila melanogaster 37565 R-DME-8876615 https://reactome.org/PathwayBrowser/#/R-DME-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Drosophila melanogaster 37565 R-DME-8876616 https://reactome.org/PathwayBrowser/#/R-DME-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Drosophila melanogaster 37565 R-DME-8876837 https://reactome.org/PathwayBrowser/#/R-DME-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Drosophila melanogaster 37565 R-DME-8877308 https://reactome.org/PathwayBrowser/#/R-DME-8877308 MADD exchanges GTP for GDP on RAB27 IEA Drosophila melanogaster 37565 R-DME-8877451 https://reactome.org/PathwayBrowser/#/R-DME-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Drosophila melanogaster 37565 R-DME-8877475 https://reactome.org/PathwayBrowser/#/R-DME-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Drosophila melanogaster 37565 R-DME-8877612 https://reactome.org/PathwayBrowser/#/R-DME-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Drosophila melanogaster 37565 R-DME-8877760 https://reactome.org/PathwayBrowser/#/R-DME-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Drosophila melanogaster 37565 R-DME-8877813 https://reactome.org/PathwayBrowser/#/R-DME-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Drosophila melanogaster 37565 R-DME-8877998 https://reactome.org/PathwayBrowser/#/R-DME-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Drosophila melanogaster 37565 R-DME-8941613 https://reactome.org/PathwayBrowser/#/R-DME-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-8941618 https://reactome.org/PathwayBrowser/#/R-DME-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-8941623 https://reactome.org/PathwayBrowser/#/R-DME-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-8941628 https://reactome.org/PathwayBrowser/#/R-DME-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 37565 R-DME-8944454 https://reactome.org/PathwayBrowser/#/R-DME-8944454 mTORC1 phosphorylates MAF1 IEA Drosophila melanogaster 37565 R-DME-8944457 https://reactome.org/PathwayBrowser/#/R-DME-8944457 MAF1 translocates to the nucleus IEA Drosophila melanogaster 37565 R-DME-8951490 https://reactome.org/PathwayBrowser/#/R-DME-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Drosophila melanogaster 37565 R-DME-8951977 https://reactome.org/PathwayBrowser/#/R-DME-8951977 Acetylated RUNX3 binds to BRD2 IEA Drosophila melanogaster 37565 R-DME-8952726 https://reactome.org/PathwayBrowser/#/R-DME-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Drosophila melanogaster 37565 R-DME-8964242 https://reactome.org/PathwayBrowser/#/R-DME-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Drosophila melanogaster 37565 R-DME-8964246 https://reactome.org/PathwayBrowser/#/R-DME-8964246 BTK in G alpha (12)-BTK complex is activated IEA Drosophila melanogaster 37565 R-DME-8964274 https://reactome.org/PathwayBrowser/#/R-DME-8964274 G alpha (12) binds BTK IEA Drosophila melanogaster 37565 R-DME-8964280 https://reactome.org/PathwayBrowser/#/R-DME-8964280 Active Gq binds BTK IEA Drosophila melanogaster 37565 R-DME-8964284 https://reactome.org/PathwayBrowser/#/R-DME-8964284 BTK in active Gq-BTK complex is activated IEA Drosophila melanogaster 37565 R-DME-8964329 https://reactome.org/PathwayBrowser/#/R-DME-8964329 G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC IEA Drosophila melanogaster 37565 R-DME-8964333 https://reactome.org/PathwayBrowser/#/R-DME-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) IEA Drosophila melanogaster 37565 R-DME-8964340 https://reactome.org/PathwayBrowser/#/R-DME-8964340 Gq-BTK complex dissociates to Active BTK and Gq IEA Drosophila melanogaster 37565 R-DME-8964599 https://reactome.org/PathwayBrowser/#/R-DME-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Drosophila melanogaster 37565 R-DME-8964604 https://reactome.org/PathwayBrowser/#/R-DME-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Drosophila melanogaster 37565 R-DME-8964614 https://reactome.org/PathwayBrowser/#/R-DME-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Drosophila melanogaster 37565 R-DME-8980691 https://reactome.org/PathwayBrowser/#/R-DME-8980691 RHOA GEFs activate RHOA IEA Drosophila melanogaster 37565 R-DME-8981353 https://reactome.org/PathwayBrowser/#/R-DME-8981353 RASA1 stimulates RAS GTPase activity IEA Drosophila melanogaster 37565 R-DME-8981355 https://reactome.org/PathwayBrowser/#/R-DME-8981355 RASA1 binds RAS:GTP IEA Drosophila melanogaster 37565 R-DME-8981637 https://reactome.org/PathwayBrowser/#/R-DME-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Drosophila melanogaster 37565 R-DME-8981926 https://reactome.org/PathwayBrowser/#/R-DME-8981926 RAC1 and CDC42 activate PAK3 IEA Drosophila melanogaster 37565 R-DME-8981931 https://reactome.org/PathwayBrowser/#/R-DME-8981931 RAC1 and CDC42 activate PAK2 IEA Drosophila melanogaster 37565 R-DME-8982017 https://reactome.org/PathwayBrowser/#/R-DME-8982017 Active G alpha (q) binds RGS proteins IEA Drosophila melanogaster 37565 R-DME-8982019 https://reactome.org/PathwayBrowser/#/R-DME-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Drosophila melanogaster 37565 R-DME-8982020 https://reactome.org/PathwayBrowser/#/R-DME-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Drosophila melanogaster 37565 R-DME-8982025 https://reactome.org/PathwayBrowser/#/R-DME-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Drosophila melanogaster 37565 R-DME-9013006 https://reactome.org/PathwayBrowser/#/R-DME-9013006 RHOA:GTP translocates to the ER membrane IEA Drosophila melanogaster 37565 R-DME-9013009 https://reactome.org/PathwayBrowser/#/R-DME-9013009 RHOA binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9013022 https://reactome.org/PathwayBrowser/#/R-DME-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Drosophila melanogaster 37565 R-DME-9013023 https://reactome.org/PathwayBrowser/#/R-DME-9013023 RHOB GEFs activate RHOB IEA Drosophila melanogaster 37565 R-DME-9013024 https://reactome.org/PathwayBrowser/#/R-DME-9013024 RHOB binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9013143 https://reactome.org/PathwayBrowser/#/R-DME-9013143 RAC1 GEFs activate RAC1 IEA Drosophila melanogaster 37565 R-DME-9013144 https://reactome.org/PathwayBrowser/#/R-DME-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Drosophila melanogaster 37565 R-DME-9013145 https://reactome.org/PathwayBrowser/#/R-DME-9013145 RAC1 binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9013159 https://reactome.org/PathwayBrowser/#/R-DME-9013159 CDC42 GEFs activate CDC42 IEA Drosophila melanogaster 37565 R-DME-9013161 https://reactome.org/PathwayBrowser/#/R-DME-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Drosophila melanogaster 37565 R-DME-9013435 https://reactome.org/PathwayBrowser/#/R-DME-9013435 RHOD auto-activates IEA Drosophila melanogaster 37565 R-DME-9013437 https://reactome.org/PathwayBrowser/#/R-DME-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Drosophila melanogaster 37565 R-DME-9013438 https://reactome.org/PathwayBrowser/#/R-DME-9013438 RHOD binds effectors at the endosome membrane IEA Drosophila melanogaster 37565 R-DME-9013452 https://reactome.org/PathwayBrowser/#/R-DME-9013452 RHOD:GTP translocates to the endosome membrane IEA Drosophila melanogaster 37565 R-DME-9014294 https://reactome.org/PathwayBrowser/#/R-DME-9014294 RAC2 binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9014295 https://reactome.org/PathwayBrowser/#/R-DME-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Drosophila melanogaster 37565 R-DME-9014296 https://reactome.org/PathwayBrowser/#/R-DME-9014296 RAC2 GEFs activate RAC2 IEA Drosophila melanogaster 37565 R-DME-9014420 https://reactome.org/PathwayBrowser/#/R-DME-9014420 RAC2 translocates to the phagocytic vesicle membrane IEA Drosophila melanogaster 37565 R-DME-9014433 https://reactome.org/PathwayBrowser/#/R-DME-9014433 RHOG GEFs activate RHOG IEA Drosophila melanogaster 37565 R-DME-9014434 https://reactome.org/PathwayBrowser/#/R-DME-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Drosophila melanogaster 37565 R-DME-9014449 https://reactome.org/PathwayBrowser/#/R-DME-9014449 RHOG binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9014454 https://reactome.org/PathwayBrowser/#/R-DME-9014454 RHOG translocates to the ER membrane IEA Drosophila melanogaster 37565 R-DME-9017488 https://reactome.org/PathwayBrowser/#/R-DME-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Drosophila melanogaster 37565 R-DME-9017491 https://reactome.org/PathwayBrowser/#/R-DME-9017491 RHOJ GEFs activate RHOJ IEA Drosophila melanogaster 37565 R-DME-9018745 https://reactome.org/PathwayBrowser/#/R-DME-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Drosophila melanogaster 37565 R-DME-9018746 https://reactome.org/PathwayBrowser/#/R-DME-9018746 RHOQ binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9018747 https://reactome.org/PathwayBrowser/#/R-DME-9018747 RHOQ GEFs activate RHOQ IEA Drosophila melanogaster 37565 R-DME-9018754 https://reactome.org/PathwayBrowser/#/R-DME-9018754 GDIs bind RHOH IEA Drosophila melanogaster 37565 R-DME-9018756 https://reactome.org/PathwayBrowser/#/R-DME-9018756 RHOH binds GTP IEA Drosophila melanogaster 37565 R-DME-9018758 https://reactome.org/PathwayBrowser/#/R-DME-9018758 RHOH binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9018766 https://reactome.org/PathwayBrowser/#/R-DME-9018766 RHOU binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9018768 https://reactome.org/PathwayBrowser/#/R-DME-9018768 RHOU auto-activates IEA Drosophila melanogaster 37565 R-DME-9018774 https://reactome.org/PathwayBrowser/#/R-DME-9018774 RHOBTB1 binds GTP IEA Drosophila melanogaster 37565 R-DME-9018778 https://reactome.org/PathwayBrowser/#/R-DME-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Drosophila melanogaster 37565 R-DME-9018785 https://reactome.org/PathwayBrowser/#/R-DME-9018785 RHOBTB2 binds GTP IEA Drosophila melanogaster 37565 R-DME-9018787 https://reactome.org/PathwayBrowser/#/R-DME-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Drosophila melanogaster 37565 R-DME-9018794 https://reactome.org/PathwayBrowser/#/R-DME-9018794 RHOV binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9018798 https://reactome.org/PathwayBrowser/#/R-DME-9018798 RHOV binds GTP IEA Drosophila melanogaster 37565 R-DME-9018804 https://reactome.org/PathwayBrowser/#/R-DME-9018804 RAC3 GEFs activate RAC3 IEA Drosophila melanogaster 37565 R-DME-9018806 https://reactome.org/PathwayBrowser/#/R-DME-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Drosophila melanogaster 37565 R-DME-9018808 https://reactome.org/PathwayBrowser/#/R-DME-9018808 RAC3 binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9018814 https://reactome.org/PathwayBrowser/#/R-DME-9018814 RHOT1 hydrolyzes GTP IEA Drosophila melanogaster 37565 R-DME-9018815 https://reactome.org/PathwayBrowser/#/R-DME-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Drosophila melanogaster 37565 R-DME-9018824 https://reactome.org/PathwayBrowser/#/R-DME-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Drosophila melanogaster 37565 R-DME-9018826 https://reactome.org/PathwayBrowser/#/R-DME-9018826 RHOT2 hydrolyzes GTP IEA Drosophila melanogaster 37565 R-DME-9018836 https://reactome.org/PathwayBrowser/#/R-DME-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Drosophila melanogaster 37565 R-DME-939265 https://reactome.org/PathwayBrowser/#/R-DME-939265 Activation of Rap1 by membrane-associated GEFs IEA Drosophila melanogaster 37565 R-DME-947535 https://reactome.org/PathwayBrowser/#/R-DME-947535 Cyclisation of GTP to precursor Z IEA Drosophila melanogaster 37565 R-DME-9607304 https://reactome.org/PathwayBrowser/#/R-DME-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Drosophila melanogaster 37565 R-DME-9610152 https://reactome.org/PathwayBrowser/#/R-DME-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Drosophila melanogaster 37565 R-DME-9610153 https://reactome.org/PathwayBrowser/#/R-DME-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Drosophila melanogaster 37565 R-DME-9610154 https://reactome.org/PathwayBrowser/#/R-DME-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Drosophila melanogaster 37565 R-DME-9610156 https://reactome.org/PathwayBrowser/#/R-DME-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Drosophila melanogaster 37565 R-DME-9610163 https://reactome.org/PathwayBrowser/#/R-DME-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Drosophila melanogaster 37565 R-DME-9624845 https://reactome.org/PathwayBrowser/#/R-DME-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Drosophila melanogaster 37565 R-DME-9624876 https://reactome.org/PathwayBrowser/#/R-DME-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Drosophila melanogaster 37565 R-DME-9624893 https://reactome.org/PathwayBrowser/#/R-DME-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Drosophila melanogaster 37565 R-DME-9632910 https://reactome.org/PathwayBrowser/#/R-DME-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Drosophila melanogaster 37565 R-DME-9632918 https://reactome.org/PathwayBrowser/#/R-DME-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Drosophila melanogaster 37565 R-DME-9639286 https://reactome.org/PathwayBrowser/#/R-DME-9639286 RRAGC,D exchanges GTP for GDP IEA Drosophila melanogaster 37565 R-DME-9640167 https://reactome.org/PathwayBrowser/#/R-DME-9640167 RRAGA,B exchanges GDP for GTP IEA Drosophila melanogaster 37565 R-DME-9640195 https://reactome.org/PathwayBrowser/#/R-DME-9640195 RRAGA,B hydrolyzes GTP IEA Drosophila melanogaster 37565 R-DME-9645598 https://reactome.org/PathwayBrowser/#/R-DME-9645598 RRAGC,D hydrolyzes GTP IEA Drosophila melanogaster 37565 R-DME-9645608 https://reactome.org/PathwayBrowser/#/R-DME-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Drosophila melanogaster 37565 R-DME-9646468 https://reactome.org/PathwayBrowser/#/R-DME-9646468 mTORC1 binds RHEB:GTP IEA Drosophila melanogaster 37565 R-DME-9649735 https://reactome.org/PathwayBrowser/#/R-DME-9649735 Intrinsic nucleotide exchange on RAS IEA Drosophila melanogaster 37565 R-DME-9649736 https://reactome.org/PathwayBrowser/#/R-DME-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Drosophila melanogaster 37565 R-DME-9653108 https://reactome.org/PathwayBrowser/#/R-DME-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Drosophila melanogaster 37565 R-DME-9654523 https://reactome.org/PathwayBrowser/#/R-DME-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Drosophila melanogaster 37565 R-DME-9654533 https://reactome.org/PathwayBrowser/#/R-DME-9654533 KRAS4B recycles to the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9657599 https://reactome.org/PathwayBrowser/#/R-DME-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Drosophila melanogaster 37565 R-DME-9657603 https://reactome.org/PathwayBrowser/#/R-DME-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Drosophila melanogaster 37565 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 37565 R-DME-9657608 https://reactome.org/PathwayBrowser/#/R-DME-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Drosophila melanogaster 37565 R-DME-9658253 https://reactome.org/PathwayBrowser/#/R-DME-9658253 RAS:GTP binds PI3K IEA Drosophila melanogaster 37565 R-DME-9660557 https://reactome.org/PathwayBrowser/#/R-DME-9660557 RAS:GTP binds RAL GDS proteins IEA Drosophila melanogaster 37565 R-DME-9690493 https://reactome.org/PathwayBrowser/#/R-DME-9690493 RHOB binds effectors on endosomes IEA Drosophila melanogaster 37565 R-DME-9690494 https://reactome.org/PathwayBrowser/#/R-DME-9690494 RHOB translocates to the endosome membrane IEA Drosophila melanogaster 37565 R-DME-9691168 https://reactome.org/PathwayBrowser/#/R-DME-9691168 RAC1 translocates to the endoplasmic reticulum membrane IEA Drosophila melanogaster 37565 R-DME-9692800 https://reactome.org/PathwayBrowser/#/R-DME-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Drosophila melanogaster 37565 R-DME-9693111 https://reactome.org/PathwayBrowser/#/R-DME-9693111 RHOF auto-activates IEA Drosophila melanogaster 37565 R-DME-9693125 https://reactome.org/PathwayBrowser/#/R-DME-9693125 RHOF binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9693198 https://reactome.org/PathwayBrowser/#/R-DME-9693198 RHOD binds effectors at the plasma membrane IEA Drosophila melanogaster 37565 R-DME-9693207 https://reactome.org/PathwayBrowser/#/R-DME-9693207 RHOD translocates to the mitochondrial outer membrane IEA Drosophila melanogaster 37565 R-DME-9693214 https://reactome.org/PathwayBrowser/#/R-DME-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Drosophila melanogaster 37565 R-DME-9693243 https://reactome.org/PathwayBrowser/#/R-DME-9693243 RHOD translocates to the Golgi membrane IEA Drosophila melanogaster 37565 R-DME-9693250 https://reactome.org/PathwayBrowser/#/R-DME-9693250 RHOD binds effectors at the Golgi membrane IEA Drosophila melanogaster 37565 R-DME-9693282 https://reactome.org/PathwayBrowser/#/R-DME-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Drosophila melanogaster 37565 R-DME-9693775 https://reactome.org/PathwayBrowser/#/R-DME-9693775 Vimar activates Miro TAS Drosophila melanogaster 37565 R-DME-9714477 https://reactome.org/PathwayBrowser/#/R-DME-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Drosophila melanogaster 37565 R-DME-9714480 https://reactome.org/PathwayBrowser/#/R-DME-9714480 RAC2 translocates to the mitochondrial membrane IEA Drosophila melanogaster 37565 R-DME-9714483 https://reactome.org/PathwayBrowser/#/R-DME-9714483 RAC2 translocates to the ER membrane IEA Drosophila melanogaster 37565 R-DME-9714694 https://reactome.org/PathwayBrowser/#/R-DME-9714694 RAC3 translocates to the endoplasmic reticulum membrane IEA Drosophila melanogaster 37565 R-DME-983259 https://reactome.org/PathwayBrowser/#/R-DME-983259 Kinesins move along microtubules consuming ATP IEA Drosophila melanogaster 37565 R-DRE-111524 https://reactome.org/PathwayBrowser/#/R-DRE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Danio rerio 37565 R-DRE-114542 https://reactome.org/PathwayBrowser/#/R-DRE-114542 RAC1,RAC2,RHOG activate PI3K IEA Danio rerio 37565 R-DRE-114552 https://reactome.org/PathwayBrowser/#/R-DRE-114552 Thrombin-activated PARs activate G12/13 IEA Danio rerio 37565 R-DRE-114558 https://reactome.org/PathwayBrowser/#/R-DRE-114558 Thrombin-activated PARs activate Gq IEA Danio rerio 37565 R-DRE-1168636 https://reactome.org/PathwayBrowser/#/R-DRE-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Danio rerio 37565 R-DRE-1250383 https://reactome.org/PathwayBrowser/#/R-DRE-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Danio rerio 37565 R-DRE-1306972 https://reactome.org/PathwayBrowser/#/R-DRE-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Danio rerio 37565 R-DRE-1433471 https://reactome.org/PathwayBrowser/#/R-DRE-1433471 Activation of RAS by p-KIT bound SOS1 IEA Danio rerio 37565 R-DRE-156823 https://reactome.org/PathwayBrowser/#/R-DRE-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Danio rerio 37565 R-DRE-156930 https://reactome.org/PathwayBrowser/#/R-DRE-156930 GTP-binding activates eEF2 IEA Danio rerio 37565 R-DRE-165195 https://reactome.org/PathwayBrowser/#/R-DRE-165195 GTP loading by Rheb IEA Danio rerio 37565 R-DRE-165680 https://reactome.org/PathwayBrowser/#/R-DRE-165680 Formation of active mTORC1 complex IEA Danio rerio 37565 R-DRE-165692 https://reactome.org/PathwayBrowser/#/R-DRE-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Danio rerio 37565 R-DRE-165718 https://reactome.org/PathwayBrowser/#/R-DRE-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Danio rerio 37565 R-DRE-167415 https://reactome.org/PathwayBrowser/#/R-DRE-167415 G-protein alpha subunit is inactivated IEA Danio rerio 37565 R-DRE-169904 https://reactome.org/PathwayBrowser/#/R-DRE-169904 C3G stimulates nucleotide exchange on Rap1 IEA Danio rerio 37565 R-DRE-170026 https://reactome.org/PathwayBrowser/#/R-DRE-170026 Protons are translocated from the intermembrane space to the matrix IEA Danio rerio 37565 R-DRE-170666 https://reactome.org/PathwayBrowser/#/R-DRE-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Danio rerio 37565 R-DRE-170671 https://reactome.org/PathwayBrowser/#/R-DRE-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Danio rerio 37565 R-DRE-170672 https://reactome.org/PathwayBrowser/#/R-DRE-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Danio rerio 37565 R-DRE-170676 https://reactome.org/PathwayBrowser/#/R-DRE-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Danio rerio 37565 R-DRE-170685 https://reactome.org/PathwayBrowser/#/R-DRE-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Danio rerio 37565 R-DRE-170686 https://reactome.org/PathwayBrowser/#/R-DRE-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Danio rerio 37565 R-DRE-177938 https://reactome.org/PathwayBrowser/#/R-DRE-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Danio rerio 37565 R-DRE-177945 https://reactome.org/PathwayBrowser/#/R-DRE-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Danio rerio 37565 R-DRE-186834 https://reactome.org/PathwayBrowser/#/R-DRE-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Danio rerio 37565 R-DRE-2029466 https://reactome.org/PathwayBrowser/#/R-DRE-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Danio rerio 37565 R-DRE-203977 https://reactome.org/PathwayBrowser/#/R-DRE-203977 SAR1 Activation And Membrane Binding IEA Danio rerio 37565 R-DRE-205039 https://reactome.org/PathwayBrowser/#/R-DRE-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Danio rerio 37565 R-DRE-205136 https://reactome.org/PathwayBrowser/#/R-DRE-205136 GTP-bound RAC contributes to JNK activation IEA Danio rerio 37565 R-DRE-210977 https://reactome.org/PathwayBrowser/#/R-DRE-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Danio rerio 37565 R-DRE-2130641 https://reactome.org/PathwayBrowser/#/R-DRE-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Danio rerio 37565 R-DRE-2130731 https://reactome.org/PathwayBrowser/#/R-DRE-2130731 Formation of COPII vesicle IEA Danio rerio 37565 R-DRE-2179407 https://reactome.org/PathwayBrowser/#/R-DRE-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Danio rerio 37565 R-DRE-2197690 https://reactome.org/PathwayBrowser/#/R-DRE-2197690 Detachment of WASP/WAVE IEA Danio rerio 37565 R-DRE-2213243 https://reactome.org/PathwayBrowser/#/R-DRE-2213243 Fusion of COPII vesicle with Golgi complex IEA Danio rerio 37565 R-DRE-2316434 https://reactome.org/PathwayBrowser/#/R-DRE-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 37565 R-DRE-2422927 https://reactome.org/PathwayBrowser/#/R-DRE-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Danio rerio 37565 R-DRE-2485182 https://reactome.org/PathwayBrowser/#/R-DRE-2485182 Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 IEA Danio rerio 37565 R-DRE-2562526 https://reactome.org/PathwayBrowser/#/R-DRE-2562526 PLK1 phosphorylates OPTN IEA Danio rerio 37565 R-DRE-354060 https://reactome.org/PathwayBrowser/#/R-DRE-354060 Translocation of RIAM to plasma membrane IEA Danio rerio 37565 R-DRE-354149 https://reactome.org/PathwayBrowser/#/R-DRE-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Danio rerio 37565 R-DRE-372819 https://reactome.org/PathwayBrowser/#/R-DRE-372819 PCK2 phosphorylates OA to yield PEP IEA Danio rerio 37565 R-DRE-377186 https://reactome.org/PathwayBrowser/#/R-DRE-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Danio rerio 37565 R-DRE-377640 https://reactome.org/PathwayBrowser/#/R-DRE-377640 Autophosphorylation of SRC IEA Danio rerio 37565 R-DRE-377641 https://reactome.org/PathwayBrowser/#/R-DRE-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Danio rerio 37565 R-DRE-377644 https://reactome.org/PathwayBrowser/#/R-DRE-377644 Release of CSK from SRC IEA Danio rerio 37565 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 37565 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 37565 R-DRE-380979 https://reactome.org/PathwayBrowser/#/R-DRE-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Danio rerio 37565 R-DRE-381727 https://reactome.org/PathwayBrowser/#/R-DRE-381727 RAP1A exchanges GDP for GTP IEA Danio rerio 37565 R-DRE-3858475 https://reactome.org/PathwayBrowser/#/R-DRE-3858475 ppDVL recruits RAC IEA Danio rerio 37565 R-DRE-3858495 https://reactome.org/PathwayBrowser/#/R-DRE-3858495 DAAM1 recruits GTP-bound RHOA IEA Danio rerio 37565 R-DRE-389788 https://reactome.org/PathwayBrowser/#/R-DRE-389788 Activation of PAKs by RAC1 and CDC42 IEA Danio rerio 37565 R-DRE-392195 https://reactome.org/PathwayBrowser/#/R-DRE-392195 Gi activation by P2Y purinoceptor 12 IEA Danio rerio 37565 R-DRE-392513 https://reactome.org/PathwayBrowser/#/R-DRE-392513 Rap1 signal termination by Rap1GAPs IEA Danio rerio 37565 R-DRE-3928576 https://reactome.org/PathwayBrowser/#/R-DRE-3928576 RHOA:GTP binds ROCK, activating it IEA Danio rerio 37565 R-DRE-3928595 https://reactome.org/PathwayBrowser/#/R-DRE-3928595 N-WASP binds ARP2/3 and G-actin IEA Danio rerio 37565 R-DRE-3928601 https://reactome.org/PathwayBrowser/#/R-DRE-3928601 CDC42 and PIP2 bind WASL, activating it IEA Danio rerio 37565 R-DRE-3928628 https://reactome.org/PathwayBrowser/#/R-DRE-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Danio rerio 37565 R-DRE-3928642 https://reactome.org/PathwayBrowser/#/R-DRE-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Danio rerio 37565 R-DRE-3928647 https://reactome.org/PathwayBrowser/#/R-DRE-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Danio rerio 37565 R-DRE-3928651 https://reactome.org/PathwayBrowser/#/R-DRE-3928651 NGEF exchanges GTP for GDP on RHOA IEA Danio rerio 37565 R-DRE-399930 https://reactome.org/PathwayBrowser/#/R-DRE-399930 Activation of PAK by Rac1 IEA Danio rerio 37565 R-DRE-399939 https://reactome.org/PathwayBrowser/#/R-DRE-399939 Autophosphorylation of PAK IEA Danio rerio 37565 R-DRE-399952 https://reactome.org/PathwayBrowser/#/R-DRE-399952 Phosphorylation of LIMK-1 by PAK IEA Danio rerio 37565 R-DRE-400037 https://reactome.org/PathwayBrowser/#/R-DRE-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Danio rerio 37565 R-DRE-400092 https://reactome.org/PathwayBrowser/#/R-DRE-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Danio rerio 37565 R-DRE-400586 https://reactome.org/PathwayBrowser/#/R-DRE-400586 G alpha (q) binds to Trio family RhoGEFs IEA Danio rerio 37565 R-DRE-4093331 https://reactome.org/PathwayBrowser/#/R-DRE-4093331 Ras:GTP binds p120-RasGAP IEA Danio rerio 37565 R-DRE-4093339 https://reactome.org/PathwayBrowser/#/R-DRE-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Danio rerio 37565 R-DRE-416358 https://reactome.org/PathwayBrowser/#/R-DRE-416358 G alpha (q) inhibits PI3K alpha IEA Danio rerio 37565 R-DRE-416546 https://reactome.org/PathwayBrowser/#/R-DRE-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Danio rerio 37565 R-DRE-416559 https://reactome.org/PathwayBrowser/#/R-DRE-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Danio rerio 37565 R-DRE-416562 https://reactome.org/PathwayBrowser/#/R-DRE-416562 p190RhoGAP binds Plexin-B1 IEA Danio rerio 37565 R-DRE-416588 https://reactome.org/PathwayBrowser/#/R-DRE-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Danio rerio 37565 R-DRE-418574 https://reactome.org/PathwayBrowser/#/R-DRE-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Danio rerio 37565 R-DRE-418582 https://reactome.org/PathwayBrowser/#/R-DRE-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Danio rerio 37565 R-DRE-418850 https://reactome.org/PathwayBrowser/#/R-DRE-418850 Activation of Cdc42 IEA Danio rerio 37565 R-DRE-418856 https://reactome.org/PathwayBrowser/#/R-DRE-418856 Activation of Rac1 IEA Danio rerio 37565 R-DRE-418874 https://reactome.org/PathwayBrowser/#/R-DRE-418874 Recruitment and activation of N-WASP by Cdc42 IEA Danio rerio 37565 R-DRE-419049 https://reactome.org/PathwayBrowser/#/R-DRE-419049 ROCK activation by RHO IEA Danio rerio 37565 R-DRE-419166 https://reactome.org/PathwayBrowser/#/R-DRE-419166 GEFs activate RhoA,B,C IEA Danio rerio 37565 R-DRE-420883 https://reactome.org/PathwayBrowser/#/R-DRE-420883 Opsins act as GEFs for G alpha-t IEA Danio rerio 37565 R-DRE-428750 https://reactome.org/PathwayBrowser/#/R-DRE-428750 Gq activation by TP receptor IEA Danio rerio 37565 R-DRE-428917 https://reactome.org/PathwayBrowser/#/R-DRE-428917 G13 activation by TP receptor IEA Danio rerio 37565 R-DRE-428941 https://reactome.org/PathwayBrowser/#/R-DRE-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Danio rerio 37565 R-DRE-432195 https://reactome.org/PathwayBrowser/#/R-DRE-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Danio rerio 37565 R-DRE-432707 https://reactome.org/PathwayBrowser/#/R-DRE-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Danio rerio 37565 R-DRE-432712 https://reactome.org/PathwayBrowser/#/R-DRE-432712 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane IEA Danio rerio 37565 R-DRE-443905 https://reactome.org/PathwayBrowser/#/R-DRE-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Danio rerio 37565 R-DRE-447074 https://reactome.org/PathwayBrowser/#/R-DRE-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Danio rerio 37565 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 37565 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 37565 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 37565 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 37565 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 37565 R-DRE-5218804 https://reactome.org/PathwayBrowser/#/R-DRE-5218804 p38 MAPK activation by VEGFR IEA Danio rerio 37565 R-DRE-5218812 https://reactome.org/PathwayBrowser/#/R-DRE-5218812 FYN phosphorylates PAK2 IEA Danio rerio 37565 R-DRE-5218814 https://reactome.org/PathwayBrowser/#/R-DRE-5218814 PAK2 autophorylates IEA Danio rerio 37565 R-DRE-5218827 https://reactome.org/PathwayBrowser/#/R-DRE-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Danio rerio 37565 R-DRE-5218832 https://reactome.org/PathwayBrowser/#/R-DRE-5218832 CDC42:GTP binds PAK2 IEA Danio rerio 37565 R-DRE-5218841 https://reactome.org/PathwayBrowser/#/R-DRE-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Danio rerio 37565 R-DRE-5228992 https://reactome.org/PathwayBrowser/#/R-DRE-5228992 ROCK1,ROCK2 are activated IEA Danio rerio 37565 R-DRE-5250209 https://reactome.org/PathwayBrowser/#/R-DRE-5250209 ARL2:GTP:ARL2BP binds SLC25A4 IEA Danio rerio 37565 R-DRE-5250210 https://reactome.org/PathwayBrowser/#/R-DRE-5250210 ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix IEA Danio rerio 37565 R-DRE-5250217 https://reactome.org/PathwayBrowser/#/R-DRE-5250217 ARL2:GTP binds ARL2BP IEA Danio rerio 37565 R-DRE-5419261 https://reactome.org/PathwayBrowser/#/R-DRE-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Danio rerio 37565 R-DRE-5620914 https://reactome.org/PathwayBrowser/#/R-DRE-5620914 ARF4:GTP binds VxPx-motifs of membrane proteins IEA Danio rerio 37565 R-DRE-5623513 https://reactome.org/PathwayBrowser/#/R-DRE-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Danio rerio 37565 R-DRE-5623519 https://reactome.org/PathwayBrowser/#/R-DRE-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Danio rerio 37565 R-DRE-5623521 https://reactome.org/PathwayBrowser/#/R-DRE-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Danio rerio 37565 R-DRE-5623622 https://reactome.org/PathwayBrowser/#/R-DRE-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Danio rerio 37565 R-DRE-5623632 https://reactome.org/PathwayBrowser/#/R-DRE-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Danio rerio 37565 R-DRE-5623667 https://reactome.org/PathwayBrowser/#/R-DRE-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Danio rerio 37565 R-DRE-5626469 https://reactome.org/PathwayBrowser/#/R-DRE-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Danio rerio 37565 R-DRE-5626507 https://reactome.org/PathwayBrowser/#/R-DRE-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Danio rerio 37565 R-DRE-5627071 https://reactome.org/PathwayBrowser/#/R-DRE-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane IEA Danio rerio 37565 R-DRE-5627072 https://reactome.org/PathwayBrowser/#/R-DRE-5627072 RHOQ binds GOPC:CFTR IEA Danio rerio 37565 R-DRE-5627775 https://reactome.org/PathwayBrowser/#/R-DRE-5627775 Autophosphorylation of PAK1,2,3 IEA Danio rerio 37565 R-DRE-5638014 https://reactome.org/PathwayBrowser/#/R-DRE-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Danio rerio 37565 R-DRE-5653957 https://reactome.org/PathwayBrowser/#/R-DRE-5653957 Rag dimer formation IEA Danio rerio 37565 R-DRE-5653968 https://reactome.org/PathwayBrowser/#/R-DRE-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Danio rerio 37565 R-DRE-5653974 https://reactome.org/PathwayBrowser/#/R-DRE-5653974 Ragulator binds Rag dimers IEA Danio rerio 37565 R-DRE-5654392 https://reactome.org/PathwayBrowser/#/R-DRE-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 37565 R-DRE-5654402 https://reactome.org/PathwayBrowser/#/R-DRE-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 37565 R-DRE-5654413 https://reactome.org/PathwayBrowser/#/R-DRE-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 37565 R-DRE-5654600 https://reactome.org/PathwayBrowser/#/R-DRE-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 37565 R-DRE-5654618 https://reactome.org/PathwayBrowser/#/R-DRE-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 37565 R-DRE-5654647 https://reactome.org/PathwayBrowser/#/R-DRE-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 37565 R-DRE-5654663 https://reactome.org/PathwayBrowser/#/R-DRE-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 37565 R-DRE-5665802 https://reactome.org/PathwayBrowser/#/R-DRE-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Danio rerio 37565 R-DRE-5665809 https://reactome.org/PathwayBrowser/#/R-DRE-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Danio rerio 37565 R-DRE-5667008 https://reactome.org/PathwayBrowser/#/R-DRE-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Danio rerio 37565 R-DRE-5668605 https://reactome.org/PathwayBrowser/#/R-DRE-5668605 RAC2:GTP binds NOX2 complex IEA Danio rerio 37565 R-DRE-5668629 https://reactome.org/PathwayBrowser/#/R-DRE-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Danio rerio 37565 R-DRE-5668714 https://reactome.org/PathwayBrowser/#/R-DRE-5668714 RAC1:GTP binds NOX1 complex IEA Danio rerio 37565 R-DRE-5668718 https://reactome.org/PathwayBrowser/#/R-DRE-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 37565 R-DRE-5668731 https://reactome.org/PathwayBrowser/#/R-DRE-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 37565 R-DRE-5668735 https://reactome.org/PathwayBrowser/#/R-DRE-5668735 RAC1:GTP binds NOX3 complex IEA Danio rerio 37565 R-DRE-5672010 https://reactome.org/PathwayBrowser/#/R-DRE-5672010 Active MTORC1 phosphorylates ULK1 IEA Danio rerio 37565 R-DRE-5672017 https://reactome.org/PathwayBrowser/#/R-DRE-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Danio rerio 37565 R-DRE-5672027 https://reactome.org/PathwayBrowser/#/R-DRE-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Danio rerio 37565 R-DRE-5672304 https://reactome.org/PathwayBrowser/#/R-DRE-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 IEA Danio rerio 37565 R-DRE-5672824 https://reactome.org/PathwayBrowser/#/R-DRE-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Danio rerio 37565 R-DRE-5672828 https://reactome.org/PathwayBrowser/#/R-DRE-5672828 mTORC1 phosphorylates AKT1S1 IEA Danio rerio 37565 R-DRE-5672965 https://reactome.org/PathwayBrowser/#/R-DRE-5672965 RAS GEFs promote RAS nucleotide exchange IEA Danio rerio 37565 R-DRE-5673768 https://reactome.org/PathwayBrowser/#/R-DRE-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Danio rerio 37565 R-DRE-5674018 https://reactome.org/PathwayBrowser/#/R-DRE-5674018 BRAP binds RAS:GTP IEA Danio rerio 37565 R-DRE-5674022 https://reactome.org/PathwayBrowser/#/R-DRE-5674022 BRAP autoubiquitinates IEA Danio rerio 37565 R-DRE-5694409 https://reactome.org/PathwayBrowser/#/R-DRE-5694409 Nucleotide exchange on RAB1 IEA Danio rerio 37565 R-DRE-5696197 https://reactome.org/PathwayBrowser/#/R-DRE-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Danio rerio 37565 R-DRE-6788611 https://reactome.org/PathwayBrowser/#/R-DRE-6788611 HYKK phosphorylates 5HLYS IEA Danio rerio 37565 R-DRE-6789092 https://reactome.org/PathwayBrowser/#/R-DRE-6789092 NOX2 generates superoxide anion from oxygen IEA Danio rerio 37565 R-DRE-6800138 https://reactome.org/PathwayBrowser/#/R-DRE-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Danio rerio 37565 R-DRE-6807868 https://reactome.org/PathwayBrowser/#/R-DRE-6807868 GBF1 stimulates ARF nucleotide exchange IEA Danio rerio 37565 R-DRE-6807872 https://reactome.org/PathwayBrowser/#/R-DRE-6807872 Active ARF recruits coatomer IEA Danio rerio 37565 R-DRE-6811417 https://reactome.org/PathwayBrowser/#/R-DRE-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Danio rerio 37565 R-DRE-6811427 https://reactome.org/PathwayBrowser/#/R-DRE-6811427 COPI vesicle uncoating at the ER IEA Danio rerio 37565 R-DRE-6814096 https://reactome.org/PathwayBrowser/#/R-DRE-6814096 ARL1:GTP binds SCOC IEA Danio rerio 37565 R-DRE-6814559 https://reactome.org/PathwayBrowser/#/R-DRE-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Danio rerio 37565 R-DRE-6814831 https://reactome.org/PathwayBrowser/#/R-DRE-6814831 TBC1D20 binds RAB1:GTP IEA Danio rerio 37565 R-DRE-6814833 https://reactome.org/PathwayBrowser/#/R-DRE-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Danio rerio 37565 R-DRE-70241 https://reactome.org/PathwayBrowser/#/R-DRE-70241 PCK1 phosphorylates OA to yield PEP IEA Danio rerio 37565 R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Danio rerio 37565 R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Danio rerio 37565 R-DRE-72621 https://reactome.org/PathwayBrowser/#/R-DRE-72621 Ribosomal scanning IEA Danio rerio 37565 R-DRE-72663 https://reactome.org/PathwayBrowser/#/R-DRE-72663 De novo formation of eIF2:GTP IEA Danio rerio 37565 R-DRE-72669 https://reactome.org/PathwayBrowser/#/R-DRE-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Danio rerio 37565 R-DRE-72691 https://reactome.org/PathwayBrowser/#/R-DRE-72691 Formation of the 43S pre-initiation complex IEA Danio rerio 37565 R-DRE-72697 https://reactome.org/PathwayBrowser/#/R-DRE-72697 Start codon recognition IEA Danio rerio 37565 R-DRE-72722 https://reactome.org/PathwayBrowser/#/R-DRE-72722 eIF2 activation IEA Danio rerio 37565 R-DRE-751029 https://reactome.org/PathwayBrowser/#/R-DRE-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Danio rerio 37565 R-DRE-77081 https://reactome.org/PathwayBrowser/#/R-DRE-77081 Formation of the CE:GMP intermediate complex IEA Danio rerio 37565 R-DRE-8847887 https://reactome.org/PathwayBrowser/#/R-DRE-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Danio rerio 37565 R-DRE-8848618 https://reactome.org/PathwayBrowser/#/R-DRE-8848618 Activation of RAC1 by the PXN:CRK complex IEA Danio rerio 37565 R-DRE-8849082 https://reactome.org/PathwayBrowser/#/R-DRE-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Danio rerio 37565 R-DRE-8849085 https://reactome.org/PathwayBrowser/#/R-DRE-8849085 ARHGAP35 binds RHOA:GTP IEA Danio rerio 37565 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 37565 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 37565 R-DRE-8851827 https://reactome.org/PathwayBrowser/#/R-DRE-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Danio rerio 37565 R-DRE-8851877 https://reactome.org/PathwayBrowser/#/R-DRE-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Danio rerio 37565 R-DRE-8854173 https://reactome.org/PathwayBrowser/#/R-DRE-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Danio rerio 37565 R-DRE-8854612 https://reactome.org/PathwayBrowser/#/R-DRE-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Danio rerio 37565 R-DRE-8875320 https://reactome.org/PathwayBrowser/#/R-DRE-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Danio rerio 37565 R-DRE-8876190 https://reactome.org/PathwayBrowser/#/R-DRE-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Danio rerio 37565 R-DRE-8876616 https://reactome.org/PathwayBrowser/#/R-DRE-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Danio rerio 37565 R-DRE-8877760 https://reactome.org/PathwayBrowser/#/R-DRE-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Danio rerio 37565 R-DRE-8941618 https://reactome.org/PathwayBrowser/#/R-DRE-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Danio rerio 37565 R-DRE-8941623 https://reactome.org/PathwayBrowser/#/R-DRE-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Danio rerio 37565 R-DRE-8941628 https://reactome.org/PathwayBrowser/#/R-DRE-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Danio rerio 37565 R-DRE-8944454 https://reactome.org/PathwayBrowser/#/R-DRE-8944454 mTORC1 phosphorylates MAF1 IEA Danio rerio 37565 R-DRE-8944457 https://reactome.org/PathwayBrowser/#/R-DRE-8944457 MAF1 translocates to the nucleus IEA Danio rerio 37565 R-DRE-8951498 https://reactome.org/PathwayBrowser/#/R-DRE-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Danio rerio 37565 R-DRE-8952716 https://reactome.org/PathwayBrowser/#/R-DRE-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Danio rerio 37565 R-DRE-8952726 https://reactome.org/PathwayBrowser/#/R-DRE-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Danio rerio 37565 R-DRE-8964242 https://reactome.org/PathwayBrowser/#/R-DRE-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Danio rerio 37565 R-DRE-8964329 https://reactome.org/PathwayBrowser/#/R-DRE-8964329 G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC IEA Danio rerio 37565 R-DRE-8980691 https://reactome.org/PathwayBrowser/#/R-DRE-8980691 RHOA GEFs activate RHOA IEA Danio rerio 37565 R-DRE-8981353 https://reactome.org/PathwayBrowser/#/R-DRE-8981353 RASA1 stimulates RAS GTPase activity IEA Danio rerio 37565 R-DRE-8981355 https://reactome.org/PathwayBrowser/#/R-DRE-8981355 RASA1 binds RAS:GTP IEA Danio rerio 37565 R-DRE-8981637 https://reactome.org/PathwayBrowser/#/R-DRE-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Danio rerio 37565 R-DRE-8981931 https://reactome.org/PathwayBrowser/#/R-DRE-8981931 RAC1 and CDC42 activate PAK2 IEA Danio rerio 37565 R-DRE-8982017 https://reactome.org/PathwayBrowser/#/R-DRE-8982017 Active G alpha (q) binds RGS proteins IEA Danio rerio 37565 R-DRE-8982019 https://reactome.org/PathwayBrowser/#/R-DRE-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Danio rerio 37565 R-DRE-8982020 https://reactome.org/PathwayBrowser/#/R-DRE-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Danio rerio 37565 R-DRE-8982025 https://reactome.org/PathwayBrowser/#/R-DRE-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Danio rerio 37565 R-DRE-9013006 https://reactome.org/PathwayBrowser/#/R-DRE-9013006 RHOA:GTP translocates to the ER membrane IEA Danio rerio 37565 R-DRE-9013009 https://reactome.org/PathwayBrowser/#/R-DRE-9013009 RHOA binds effectors at the plasma membrane IEA Danio rerio 37565 R-DRE-9013143 https://reactome.org/PathwayBrowser/#/R-DRE-9013143 RAC1 GEFs activate RAC1 IEA Danio rerio 37565 R-DRE-9013144 https://reactome.org/PathwayBrowser/#/R-DRE-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Danio rerio 37565 R-DRE-9013159 https://reactome.org/PathwayBrowser/#/R-DRE-9013159 CDC42 GEFs activate CDC42 IEA Danio rerio 37565 R-DRE-9013161 https://reactome.org/PathwayBrowser/#/R-DRE-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Danio rerio 37565 R-DRE-9013435 https://reactome.org/PathwayBrowser/#/R-DRE-9013435 RHOD auto-activates IEA Danio rerio 37565 R-DRE-9013437 https://reactome.org/PathwayBrowser/#/R-DRE-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Danio rerio 37565 R-DRE-9013452 https://reactome.org/PathwayBrowser/#/R-DRE-9013452 RHOD:GTP translocates to the endosome membrane IEA Danio rerio 37565 R-DRE-9014294 https://reactome.org/PathwayBrowser/#/R-DRE-9014294 RAC2 binds effectors at the plasma membrane IEA Danio rerio 37565 R-DRE-9014295 https://reactome.org/PathwayBrowser/#/R-DRE-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Danio rerio 37565 R-DRE-9014296 https://reactome.org/PathwayBrowser/#/R-DRE-9014296 RAC2 GEFs activate RAC2 IEA Danio rerio 37565 R-DRE-9014420 https://reactome.org/PathwayBrowser/#/R-DRE-9014420 RAC2 translocates to the phagocytic vesicle membrane IEA Danio rerio 37565 R-DRE-9014424 https://reactome.org/PathwayBrowser/#/R-DRE-9014424 RAC2 binds effectors at the phagocytic vesicle membrane IEA Danio rerio 37565 R-DRE-9014433 https://reactome.org/PathwayBrowser/#/R-DRE-9014433 RHOG GEFs activate RHOG IEA Danio rerio 37565 R-DRE-9014434 https://reactome.org/PathwayBrowser/#/R-DRE-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Danio rerio 37565 R-DRE-9014449 https://reactome.org/PathwayBrowser/#/R-DRE-9014449 RHOG binds effectors at the plasma membrane IEA Danio rerio 37565 R-DRE-9014454 https://reactome.org/PathwayBrowser/#/R-DRE-9014454 RHOG translocates to the ER membrane IEA Danio rerio 37565 R-DRE-9018745 https://reactome.org/PathwayBrowser/#/R-DRE-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Danio rerio 37565 R-DRE-9018746 https://reactome.org/PathwayBrowser/#/R-DRE-9018746 RHOQ binds effectors at the plasma membrane IEA Danio rerio 37565 R-DRE-9018766 https://reactome.org/PathwayBrowser/#/R-DRE-9018766 RHOU binds effectors at the plasma membrane IEA Danio rerio 37565 R-DRE-9018768 https://reactome.org/PathwayBrowser/#/R-DRE-9018768 RHOU auto-activates IEA Danio rerio 37565 R-DRE-9018794 https://reactome.org/PathwayBrowser/#/R-DRE-9018794 RHOV binds effectors at the plasma membrane IEA Danio rerio 37565 R-DRE-9018798 https://reactome.org/PathwayBrowser/#/R-DRE-9018798 RHOV binds GTP IEA Danio rerio 37565 R-DRE-9018804 https://reactome.org/PathwayBrowser/#/R-DRE-9018804 RAC3 GEFs activate RAC3 IEA Danio rerio 37565 R-DRE-9018806 https://reactome.org/PathwayBrowser/#/R-DRE-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Danio rerio 37565 R-DRE-9018814 https://reactome.org/PathwayBrowser/#/R-DRE-9018814 RHOT1 hydrolyzes GTP IEA Danio rerio 37565 R-DRE-9018826 https://reactome.org/PathwayBrowser/#/R-DRE-9018826 RHOT2 hydrolyzes GTP IEA Danio rerio 37565 R-DRE-9018836 https://reactome.org/PathwayBrowser/#/R-DRE-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Danio rerio 37565 R-DRE-9610153 https://reactome.org/PathwayBrowser/#/R-DRE-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Danio rerio 37565 R-DRE-9610156 https://reactome.org/PathwayBrowser/#/R-DRE-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Danio rerio 37565 R-DRE-9624845 https://reactome.org/PathwayBrowser/#/R-DRE-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Danio rerio 37565 R-DRE-9624876 https://reactome.org/PathwayBrowser/#/R-DRE-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Danio rerio 37565 R-DRE-9624893 https://reactome.org/PathwayBrowser/#/R-DRE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Danio rerio 37565 R-DRE-9626848 https://reactome.org/PathwayBrowser/#/R-DRE-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Danio rerio 37565 R-DRE-9639286 https://reactome.org/PathwayBrowser/#/R-DRE-9639286 RRAGC,D exchanges GTP for GDP IEA Danio rerio 37565 R-DRE-9640167 https://reactome.org/PathwayBrowser/#/R-DRE-9640167 RRAGA,B exchanges GDP for GTP IEA Danio rerio 37565 R-DRE-9640168 https://reactome.org/PathwayBrowser/#/R-DRE-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Danio rerio 37565 R-DRE-9640195 https://reactome.org/PathwayBrowser/#/R-DRE-9640195 RRAGA,B hydrolyzes GTP IEA Danio rerio 37565 R-DRE-9645598 https://reactome.org/PathwayBrowser/#/R-DRE-9645598 RRAGC,D hydrolyzes GTP IEA Danio rerio 37565 R-DRE-9645608 https://reactome.org/PathwayBrowser/#/R-DRE-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Danio rerio 37565 R-DRE-9646468 https://reactome.org/PathwayBrowser/#/R-DRE-9646468 mTORC1 binds RHEB:GTP IEA Danio rerio 37565 R-DRE-9646679 https://reactome.org/PathwayBrowser/#/R-DRE-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Danio rerio 37565 R-DRE-9649735 https://reactome.org/PathwayBrowser/#/R-DRE-9649735 Intrinsic nucleotide exchange on RAS IEA Danio rerio 37565 R-DRE-9649736 https://reactome.org/PathwayBrowser/#/R-DRE-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Danio rerio 37565 R-DRE-9658253 https://reactome.org/PathwayBrowser/#/R-DRE-9658253 RAS:GTP binds PI3K IEA Danio rerio 37565 R-DRE-9658445 https://reactome.org/PathwayBrowser/#/R-DRE-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Danio rerio 37565 R-DRE-9660557 https://reactome.org/PathwayBrowser/#/R-DRE-9660557 RAS:GTP binds RAL GDS proteins IEA Danio rerio 37565 R-DRE-9691168 https://reactome.org/PathwayBrowser/#/R-DRE-9691168 RAC1 translocates to the endoplasmic reticulum membrane IEA Danio rerio 37565 R-DRE-9692800 https://reactome.org/PathwayBrowser/#/R-DRE-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Danio rerio 37565 R-DRE-9693111 https://reactome.org/PathwayBrowser/#/R-DRE-9693111 RHOF auto-activates IEA Danio rerio 37565 R-DRE-9693125 https://reactome.org/PathwayBrowser/#/R-DRE-9693125 RHOF binds effectors at the plasma membrane IEA Danio rerio 37565 R-DRE-9693198 https://reactome.org/PathwayBrowser/#/R-DRE-9693198 RHOD binds effectors at the plasma membrane IEA Danio rerio 37565 R-DRE-9693207 https://reactome.org/PathwayBrowser/#/R-DRE-9693207 RHOD translocates to the mitochondrial outer membrane IEA Danio rerio 37565 R-DRE-9693214 https://reactome.org/PathwayBrowser/#/R-DRE-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Danio rerio 37565 R-DRE-9693243 https://reactome.org/PathwayBrowser/#/R-DRE-9693243 RHOD translocates to the Golgi membrane IEA Danio rerio 37565 R-DRE-9693282 https://reactome.org/PathwayBrowser/#/R-DRE-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Danio rerio 37565 R-DRE-9696266 https://reactome.org/PathwayBrowser/#/R-DRE-9696266 RND2 binds effectors IEA Danio rerio 37565 R-DRE-9696267 https://reactome.org/PathwayBrowser/#/R-DRE-9696267 RND3 binds GTP IEA Danio rerio 37565 R-DRE-9696268 https://reactome.org/PathwayBrowser/#/R-DRE-9696268 RND3 binds effectors IEA Danio rerio 37565 R-DRE-9696271 https://reactome.org/PathwayBrowser/#/R-DRE-9696271 RND1 binds effectors IEA Danio rerio 37565 R-DRE-9696274 https://reactome.org/PathwayBrowser/#/R-DRE-9696274 RND1 binds GTP IEA Danio rerio 37565 R-DRE-9696275 https://reactome.org/PathwayBrowser/#/R-DRE-9696275 RND2 binds GTP IEA Danio rerio 37565 R-DRE-9714477 https://reactome.org/PathwayBrowser/#/R-DRE-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Danio rerio 37565 R-DRE-9714480 https://reactome.org/PathwayBrowser/#/R-DRE-9714480 RAC2 translocates to the mitochondrial membrane IEA Danio rerio 37565 R-DRE-9714483 https://reactome.org/PathwayBrowser/#/R-DRE-9714483 RAC2 translocates to the ER membrane IEA Danio rerio 37565 R-DRE-9714694 https://reactome.org/PathwayBrowser/#/R-DRE-9714694 RAC3 translocates to the endoplasmic reticulum membrane IEA Danio rerio 37565 R-DRE-983424 https://reactome.org/PathwayBrowser/#/R-DRE-983424 Budding of COPII coated vesicle IEA Danio rerio 37565 R-DRE-983425 https://reactome.org/PathwayBrowser/#/R-DRE-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Danio rerio 37565 R-GGA-1008248 https://reactome.org/PathwayBrowser/#/R-GGA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Gallus gallus 37565 R-GGA-111524 https://reactome.org/PathwayBrowser/#/R-GGA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Gallus gallus 37565 R-GGA-111879 https://reactome.org/PathwayBrowser/#/R-GGA-111879 PIP2 hydrolysis IEA Gallus gallus 37565 R-GGA-112037 https://reactome.org/PathwayBrowser/#/R-GGA-112037 Inactivation of PLC beta IEA Gallus gallus 37565 R-GGA-112271 https://reactome.org/PathwayBrowser/#/R-GGA-112271 The receptor:G-protein complex dissociates IEA Gallus gallus 37565 R-GGA-114542 https://reactome.org/PathwayBrowser/#/R-GGA-114542 RAC1,RAC2,RHOG activate PI3K IEA Gallus gallus 37565 R-GGA-114552 https://reactome.org/PathwayBrowser/#/R-GGA-114552 Thrombin-activated PARs activate G12/13 IEA Gallus gallus 37565 R-GGA-114558 https://reactome.org/PathwayBrowser/#/R-GGA-114558 Thrombin-activated PARs activate Gq IEA Gallus gallus 37565 R-GGA-114688 https://reactome.org/PathwayBrowser/#/R-GGA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Gallus gallus 37565 R-GGA-1168636 https://reactome.org/PathwayBrowser/#/R-GGA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Gallus gallus 37565 R-GGA-1250383 https://reactome.org/PathwayBrowser/#/R-GGA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Gallus gallus 37565 R-GGA-1306972 https://reactome.org/PathwayBrowser/#/R-GGA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Gallus gallus 37565 R-GGA-1433471 https://reactome.org/PathwayBrowser/#/R-GGA-1433471 Activation of RAS by p-KIT bound SOS1 IEA Gallus gallus 37565 R-GGA-1474146 https://reactome.org/PathwayBrowser/#/R-GGA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Gallus gallus 37565 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus 37565 R-GGA-156930 https://reactome.org/PathwayBrowser/#/R-GGA-156930 GTP-binding activates eEF2 IEA Gallus gallus 37565 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus 37565 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus 37565 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus 37565 R-GGA-165195 https://reactome.org/PathwayBrowser/#/R-GGA-165195 GTP loading by Rheb IEA Gallus gallus 37565 R-GGA-165680 https://reactome.org/PathwayBrowser/#/R-GGA-165680 Formation of active mTORC1 complex IEA Gallus gallus 37565 R-GGA-165692 https://reactome.org/PathwayBrowser/#/R-GGA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Gallus gallus 37565 R-GGA-165718 https://reactome.org/PathwayBrowser/#/R-GGA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Gallus gallus 37565 R-GGA-167415 https://reactome.org/PathwayBrowser/#/R-GGA-167415 G-protein alpha subunit is inactivated IEA Gallus gallus 37565 R-GGA-167429 https://reactome.org/PathwayBrowser/#/R-GGA-167429 The receptor:G-protein complex binds GTP IEA Gallus gallus 37565 R-GGA-169904 https://reactome.org/PathwayBrowser/#/R-GGA-169904 C3G stimulates nucleotide exchange on Rap1 IEA Gallus gallus 37565 R-GGA-170026 https://reactome.org/PathwayBrowser/#/R-GGA-170026 Protons are translocated from the intermembrane space to the matrix IEA Gallus gallus 37565 R-GGA-170666 https://reactome.org/PathwayBrowser/#/R-GGA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus 37565 R-GGA-170671 https://reactome.org/PathwayBrowser/#/R-GGA-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Gallus gallus 37565 R-GGA-170672 https://reactome.org/PathwayBrowser/#/R-GGA-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Gallus gallus 37565 R-GGA-170676 https://reactome.org/PathwayBrowser/#/R-GGA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Gallus gallus 37565 R-GGA-170685 https://reactome.org/PathwayBrowser/#/R-GGA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus 37565 R-GGA-170686 https://reactome.org/PathwayBrowser/#/R-GGA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Gallus gallus 37565 R-GGA-170986 https://reactome.org/PathwayBrowser/#/R-GGA-170986 Ral-GDS binds to Ras-GTP IEA Gallus gallus 37565 R-GGA-177938 https://reactome.org/PathwayBrowser/#/R-GGA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Gallus gallus 37565 R-GGA-177945 https://reactome.org/PathwayBrowser/#/R-GGA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Gallus gallus 37565 R-GGA-183002 https://reactome.org/PathwayBrowser/#/R-GGA-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Gallus gallus 37565 R-GGA-183084 https://reactome.org/PathwayBrowser/#/R-GGA-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Gallus gallus 37565 R-GGA-183094 https://reactome.org/PathwayBrowser/#/R-GGA-183094 CDC42:GTP binds CBL:Beta-Pix IEA Gallus gallus 37565 R-GGA-186834 https://reactome.org/PathwayBrowser/#/R-GGA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Gallus gallus 37565 R-GGA-194518 https://reactome.org/PathwayBrowser/#/R-GGA-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Gallus gallus 37565 R-GGA-2029451 https://reactome.org/PathwayBrowser/#/R-GGA-2029451 Activation of RAC1 by VAV IEA Gallus gallus 37565 R-GGA-2029454 https://reactome.org/PathwayBrowser/#/R-GGA-2029454 Autophosphorylation of PAK1 IEA Gallus gallus 37565 R-GGA-2029456 https://reactome.org/PathwayBrowser/#/R-GGA-2029456 RAC1 and CDC42 activate PAK1 IEA Gallus gallus 37565 R-GGA-2029465 https://reactome.org/PathwayBrowser/#/R-GGA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Gallus gallus 37565 R-GGA-2029466 https://reactome.org/PathwayBrowser/#/R-GGA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Gallus gallus 37565 R-GGA-2029467 https://reactome.org/PathwayBrowser/#/R-GGA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Gallus gallus 37565 R-GGA-2029469 https://reactome.org/PathwayBrowser/#/R-GGA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Gallus gallus 37565 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus 37565 R-GGA-203979 https://reactome.org/PathwayBrowser/#/R-GGA-203979 Coat Assembly IEA Gallus gallus 37565 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus 37565 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus 37565 R-GGA-205136 https://reactome.org/PathwayBrowser/#/R-GGA-205136 GTP-bound RAC contributes to JNK activation IEA Gallus gallus 37565 R-GGA-2065539 https://reactome.org/PathwayBrowser/#/R-GGA-2065539 SREBP1A,1C,2:Importin beta-1 dissociates IEA Gallus gallus 37565 R-GGA-210977 https://reactome.org/PathwayBrowser/#/R-GGA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Gallus gallus 37565 R-GGA-2130194 https://reactome.org/PathwayBrowser/#/R-GGA-2130194 ABL phosphorylates WAVEs IEA Gallus gallus 37565 R-GGA-2130641 https://reactome.org/PathwayBrowser/#/R-GGA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Gallus gallus 37565 R-GGA-2130725 https://reactome.org/PathwayBrowser/#/R-GGA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Gallus gallus 37565 R-GGA-2179407 https://reactome.org/PathwayBrowser/#/R-GGA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Gallus gallus 37565 R-GGA-2197690 https://reactome.org/PathwayBrowser/#/R-GGA-2197690 Detachment of WASP/WAVE IEA Gallus gallus 37565 R-GGA-2197698 https://reactome.org/PathwayBrowser/#/R-GGA-2197698 Src phosphorylate WASP,N-WASP IEA Gallus gallus 37565 R-GGA-2214351 https://reactome.org/PathwayBrowser/#/R-GGA-2214351 PLK1 phosphorylates GORASP1 IEA Gallus gallus 37565 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 37565 R-GGA-2422927 https://reactome.org/PathwayBrowser/#/R-GGA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Gallus gallus 37565 R-GGA-2424476 https://reactome.org/PathwayBrowser/#/R-GGA-2424476 Activation of RAC1 by VAV2/3 IEA Gallus gallus 37565 R-GGA-2424477 https://reactome.org/PathwayBrowser/#/R-GGA-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Gallus gallus 37565 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus 37565 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus 37565 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus 37565 R-GGA-2562526 https://reactome.org/PathwayBrowser/#/R-GGA-2562526 PLK1 phosphorylates OPTN IEA Gallus gallus 37565 R-GGA-2730840 https://reactome.org/PathwayBrowser/#/R-GGA-2730840 Activation of RAC1 by VAV IEA Gallus gallus 37565 R-GGA-2730856 https://reactome.org/PathwayBrowser/#/R-GGA-2730856 Autophosphorylation of PAK IEA Gallus gallus 37565 R-GGA-2730889 https://reactome.org/PathwayBrowser/#/R-GGA-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Gallus gallus 37565 R-GGA-350769 https://reactome.org/PathwayBrowser/#/R-GGA-350769 trans-Golgi Network Coat Activation IEA Gallus gallus 37565 R-GGA-354060 https://reactome.org/PathwayBrowser/#/R-GGA-354060 Translocation of RIAM to plasma membrane IEA Gallus gallus 37565 R-GGA-354066 https://reactome.org/PathwayBrowser/#/R-GGA-354066 Translocation of PTK2 to Focal complexes IEA Gallus gallus 37565 R-GGA-354073 https://reactome.org/PathwayBrowser/#/R-GGA-354073 Autophosphorylation of PTK2 at Y397 IEA Gallus gallus 37565 R-GGA-354077 https://reactome.org/PathwayBrowser/#/R-GGA-354077 Integrin alphaIIb beta3 activation IEA Gallus gallus 37565 R-GGA-354087 https://reactome.org/PathwayBrowser/#/R-GGA-354087 Recruitment of GRB2 to p-PTK2 IEA Gallus gallus 37565 R-GGA-354097 https://reactome.org/PathwayBrowser/#/R-GGA-354097 Activation of Talin IEA Gallus gallus 37565 R-GGA-354124 https://reactome.org/PathwayBrowser/#/R-GGA-354124 Phosphorylation of pPTK2 by SRC IEA Gallus gallus 37565 R-GGA-354149 https://reactome.org/PathwayBrowser/#/R-GGA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Gallus gallus 37565 R-GGA-354165 https://reactome.org/PathwayBrowser/#/R-GGA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Gallus gallus 37565 R-GGA-354173 https://reactome.org/PathwayBrowser/#/R-GGA-354173 Activation of Rap1 by cytosolic GEFs IEA Gallus gallus 37565 R-GGA-372693 https://reactome.org/PathwayBrowser/#/R-GGA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Gallus gallus 37565 R-GGA-372697 https://reactome.org/PathwayBrowser/#/R-GGA-372697 Crk binding to p130cas IEA Gallus gallus 37565 R-GGA-372705 https://reactome.org/PathwayBrowser/#/R-GGA-372705 Recruitment of BCAR1 to PTK2 complex IEA Gallus gallus 37565 R-GGA-372724 https://reactome.org/PathwayBrowser/#/R-GGA-372724 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] TAS Gallus gallus 37565 R-GGA-372741 https://reactome.org/PathwayBrowser/#/R-GGA-372741 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] TAS Gallus gallus 37565 R-GGA-372819 https://reactome.org/PathwayBrowser/#/R-GGA-372819 PCK2 phosphorylates OA to yield PEP IEA Gallus gallus 37565 R-GGA-372980 https://reactome.org/PathwayBrowser/#/R-GGA-372980 succinylCoA + GDP + Pi <=> succinate + CoASH + GTP TAS Gallus gallus 37565 R-GGA-373148 https://reactome.org/PathwayBrowser/#/R-GGA-373148 succinate + CoASH + GTP <=> succinylCoA + GDP + Pi TAS Gallus gallus 37565 R-GGA-377186 https://reactome.org/PathwayBrowser/#/R-GGA-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Gallus gallus 37565 R-GGA-377640 https://reactome.org/PathwayBrowser/#/R-GGA-377640 Autophosphorylation of SRC IEA Gallus gallus 37565 R-GGA-377641 https://reactome.org/PathwayBrowser/#/R-GGA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Gallus gallus 37565 R-GGA-377643 https://reactome.org/PathwayBrowser/#/R-GGA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Gallus gallus 37565 R-GGA-377644 https://reactome.org/PathwayBrowser/#/R-GGA-377644 Release of CSK from SRC IEA Gallus gallus 37565 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 37565 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 37565 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 37565 R-GGA-380979 https://reactome.org/PathwayBrowser/#/R-GGA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Gallus gallus 37565 R-GGA-381727 https://reactome.org/PathwayBrowser/#/R-GGA-381727 RAP1A exchanges GDP for GTP IEA Gallus gallus 37565 R-GGA-389348 https://reactome.org/PathwayBrowser/#/R-GGA-389348 Activation of Rac1 by pVav1 IEA Gallus gallus 37565 R-GGA-389350 https://reactome.org/PathwayBrowser/#/R-GGA-389350 Activation of Cdc42 by pVav1 IEA Gallus gallus 37565 R-GGA-389788 https://reactome.org/PathwayBrowser/#/R-GGA-389788 Activation of PAKs by RAC1 and CDC42 IEA Gallus gallus 37565 R-GGA-392054 https://reactome.org/PathwayBrowser/#/R-GGA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Gallus gallus 37565 R-GGA-392064 https://reactome.org/PathwayBrowser/#/R-GGA-392064 G alpha (z) inhibits adenylate cyclase IEA Gallus gallus 37565 R-GGA-392195 https://reactome.org/PathwayBrowser/#/R-GGA-392195 Gi activation by P2Y purinoceptor 12 IEA Gallus gallus 37565 R-GGA-392513 https://reactome.org/PathwayBrowser/#/R-GGA-392513 Rap1 signal termination by Rap1GAPs IEA Gallus gallus 37565 R-GGA-392835 https://reactome.org/PathwayBrowser/#/R-GGA-392835 Rap1 sequesters Raf1 to inhibit ERK cascade IEA Gallus gallus 37565 R-GGA-3928576 https://reactome.org/PathwayBrowser/#/R-GGA-3928576 RHOA:GTP binds ROCK, activating it IEA Gallus gallus 37565 R-GGA-3928592 https://reactome.org/PathwayBrowser/#/R-GGA-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Gallus gallus 37565 R-GGA-3928595 https://reactome.org/PathwayBrowser/#/R-GGA-3928595 N-WASP binds ARP2/3 and G-actin IEA Gallus gallus 37565 R-GGA-3928601 https://reactome.org/PathwayBrowser/#/R-GGA-3928601 CDC42 and PIP2 bind WASL, activating it IEA Gallus gallus 37565 R-GGA-3928612 https://reactome.org/PathwayBrowser/#/R-GGA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 37565 R-GGA-3928619 https://reactome.org/PathwayBrowser/#/R-GGA-3928619 PAK1 binds RAC1:GTP IEA Gallus gallus 37565 R-GGA-3928620 https://reactome.org/PathwayBrowser/#/R-GGA-3928620 PAK1 autophosphorylates IEA Gallus gallus 37565 R-GGA-3928625 https://reactome.org/PathwayBrowser/#/R-GGA-3928625 PAKs autophosphorylate IEA Gallus gallus 37565 R-GGA-3928628 https://reactome.org/PathwayBrowser/#/R-GGA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 37565 R-GGA-3928633 https://reactome.org/PathwayBrowser/#/R-GGA-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Gallus gallus 37565 R-GGA-3928640 https://reactome.org/PathwayBrowser/#/R-GGA-3928640 PAKs phosphorylate MLC IEA Gallus gallus 37565 R-GGA-3928641 https://reactome.org/PathwayBrowser/#/R-GGA-3928641 PAK binds RAC and bPIX IEA Gallus gallus 37565 R-GGA-3928642 https://reactome.org/PathwayBrowser/#/R-GGA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 37565 R-GGA-3928647 https://reactome.org/PathwayBrowser/#/R-GGA-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Gallus gallus 37565 R-GGA-3928651 https://reactome.org/PathwayBrowser/#/R-GGA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Gallus gallus 37565 R-GGA-3965444 https://reactome.org/PathwayBrowser/#/R-GGA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Gallus gallus 37565 R-GGA-3965447 https://reactome.org/PathwayBrowser/#/R-GGA-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Gallus gallus 37565 R-GGA-397835 https://reactome.org/PathwayBrowser/#/R-GGA-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Gallus gallus 37565 R-GGA-397891 https://reactome.org/PathwayBrowser/#/R-GGA-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Gallus gallus 37565 R-GGA-398184 https://reactome.org/PathwayBrowser/#/R-GGA-398184 LARG activation by G alpha 12/13 IEA Gallus gallus 37565 R-GGA-398185 https://reactome.org/PathwayBrowser/#/R-GGA-398185 LARG binds plexin B1 IEA Gallus gallus 37565 R-GGA-399930 https://reactome.org/PathwayBrowser/#/R-GGA-399930 Activation of PAK by Rac1 IEA Gallus gallus 37565 R-GGA-399939 https://reactome.org/PathwayBrowser/#/R-GGA-399939 Autophosphorylation of PAK IEA Gallus gallus 37565 R-GGA-399952 https://reactome.org/PathwayBrowser/#/R-GGA-399952 Phosphorylation of LIMK-1 by PAK IEA Gallus gallus 37565 R-GGA-399998 https://reactome.org/PathwayBrowser/#/R-GGA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Gallus gallus 37565 R-GGA-400586 https://reactome.org/PathwayBrowser/#/R-GGA-400586 G alpha (q) binds to Trio family RhoGEFs IEA Gallus gallus 37565 R-GGA-400677 https://reactome.org/PathwayBrowser/#/R-GGA-400677 Rnd1 interacts with Plexin-B1:Sema4D IEA Gallus gallus 37565 R-GGA-400682 https://reactome.org/PathwayBrowser/#/R-GGA-400682 Active Rac1 interacts with Plexin-B1:Sema4D IEA Gallus gallus 37565 R-GGA-4086392 https://reactome.org/PathwayBrowser/#/R-GGA-4086392 PDE6 hydrolyses cGMP to GMP IEA Gallus gallus 37565 R-GGA-4093331 https://reactome.org/PathwayBrowser/#/R-GGA-4093331 Ras:GTP binds p120-RasGAP IEA Gallus gallus 37565 R-GGA-4093336 https://reactome.org/PathwayBrowser/#/R-GGA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 37565 R-GGA-4093339 https://reactome.org/PathwayBrowser/#/R-GGA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Gallus gallus 37565 R-GGA-416358 https://reactome.org/PathwayBrowser/#/R-GGA-416358 G alpha (q) inhibits PI3K alpha IEA Gallus gallus 37565 R-GGA-416516 https://reactome.org/PathwayBrowser/#/R-GGA-416516 GRK2 sequesters activated Gq IEA Gallus gallus 37565 R-GGA-416559 https://reactome.org/PathwayBrowser/#/R-GGA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Gallus gallus 37565 R-GGA-416562 https://reactome.org/PathwayBrowser/#/R-GGA-416562 p190RhoGAP binds Plexin-B1 IEA Gallus gallus 37565 R-GGA-416588 https://reactome.org/PathwayBrowser/#/R-GGA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Gallus gallus 37565 R-GGA-418574 https://reactome.org/PathwayBrowser/#/R-GGA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Gallus gallus 37565 R-GGA-418576 https://reactome.org/PathwayBrowser/#/R-GGA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Gallus gallus 37565 R-GGA-418582 https://reactome.org/PathwayBrowser/#/R-GGA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Gallus gallus 37565 R-GGA-419049 https://reactome.org/PathwayBrowser/#/R-GGA-419049 ROCK activation by RHO IEA Gallus gallus 37565 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus 37565 R-GGA-420883 https://reactome.org/PathwayBrowser/#/R-GGA-420883 Opsins act as GEFs for G alpha-t IEA Gallus gallus 37565 R-GGA-421201 https://reactome.org/PathwayBrowser/#/R-GGA-421201 inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate IEA Gallus gallus 37565 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus 37565 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus 37565 R-GGA-428750 https://reactome.org/PathwayBrowser/#/R-GGA-428750 Gq activation by TP receptor IEA Gallus gallus 37565 R-GGA-428752 https://reactome.org/PathwayBrowser/#/R-GGA-428752 Dissociation of the TP:Gq complex IEA Gallus gallus 37565 R-GGA-428917 https://reactome.org/PathwayBrowser/#/R-GGA-428917 G13 activation by TP receptor IEA Gallus gallus 37565 R-GGA-428918 https://reactome.org/PathwayBrowser/#/R-GGA-428918 Dissociation of the TP:G13 complex IEA Gallus gallus 37565 R-GGA-428941 https://reactome.org/PathwayBrowser/#/R-GGA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Gallus gallus 37565 R-GGA-429415 https://reactome.org/PathwayBrowser/#/R-GGA-429415 SYK binds to integrin alphaIIb beta3 IEA Gallus gallus 37565 R-GGA-429441 https://reactome.org/PathwayBrowser/#/R-GGA-429441 SYK activation by SRC IEA Gallus gallus 37565 R-GGA-432096 https://reactome.org/PathwayBrowser/#/R-GGA-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Gallus gallus 37565 R-GGA-432706 https://reactome.org/PathwayBrowser/#/R-GGA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Gallus gallus 37565 R-GGA-432707 https://reactome.org/PathwayBrowser/#/R-GGA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Gallus gallus 37565 R-GGA-442291 https://reactome.org/PathwayBrowser/#/R-GGA-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Gallus gallus 37565 R-GGA-442314 https://reactome.org/PathwayBrowser/#/R-GGA-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Gallus gallus 37565 R-GGA-443905 https://reactome.org/PathwayBrowser/#/R-GGA-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Gallus gallus 37565 R-GGA-443910 https://reactome.org/PathwayBrowser/#/R-GGA-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Gallus gallus 37565 R-GGA-445064 https://reactome.org/PathwayBrowser/#/R-GGA-445064 Activation of Rac1 by VAV2 IEA Gallus gallus 37565 R-GGA-445072 https://reactome.org/PathwayBrowser/#/R-GGA-445072 Interaction of PAK1 with Rac1-GTP IEA Gallus gallus 37565 R-GGA-447074 https://reactome.org/PathwayBrowser/#/R-GGA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Gallus gallus 37565 R-GGA-448958 https://reactome.org/PathwayBrowser/#/R-GGA-448958 Nuclear translocation of p38 MAPK IEA Gallus gallus 37565 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 37565 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 37565 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 37565 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 37565 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 37565 R-GGA-5218804 https://reactome.org/PathwayBrowser/#/R-GGA-5218804 p38 MAPK activation by VEGFR IEA Gallus gallus 37565 R-GGA-5218812 https://reactome.org/PathwayBrowser/#/R-GGA-5218812 FYN phosphorylates PAK2 IEA Gallus gallus 37565 R-GGA-5218814 https://reactome.org/PathwayBrowser/#/R-GGA-5218814 PAK2 autophorylates IEA Gallus gallus 37565 R-GGA-5218826 https://reactome.org/PathwayBrowser/#/R-GGA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Gallus gallus 37565 R-GGA-5218827 https://reactome.org/PathwayBrowser/#/R-GGA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Gallus gallus 37565 R-GGA-5218832 https://reactome.org/PathwayBrowser/#/R-GGA-5218832 CDC42:GTP binds PAK2 IEA Gallus gallus 37565 R-GGA-5218839 https://reactome.org/PathwayBrowser/#/R-GGA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Gallus gallus 37565 R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus 37565 R-GGA-5218845 https://reactome.org/PathwayBrowser/#/R-GGA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Gallus gallus 37565 R-GGA-5218850 https://reactome.org/PathwayBrowser/#/R-GGA-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 37565 R-GGA-5228992 https://reactome.org/PathwayBrowser/#/R-GGA-5228992 ROCK1,ROCK2 are activated IEA Gallus gallus 37565 R-GGA-5357445 https://reactome.org/PathwayBrowser/#/R-GGA-5357445 PAK1-3 dimer disassociates IEA Gallus gallus 37565 R-GGA-5357472 https://reactome.org/PathwayBrowser/#/R-GGA-5357472 PAK1-3 autophosphorylates IEA Gallus gallus 37565 R-GGA-5357483 https://reactome.org/PathwayBrowser/#/R-GGA-5357483 RAC1 binds PAK1-3 IEA Gallus gallus 37565 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus 37565 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus 37565 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Gallus gallus 37565 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus 37565 R-GGA-555065 https://reactome.org/PathwayBrowser/#/R-GGA-555065 Formation of clathrin coated vesicle IEA Gallus gallus 37565 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus 37565 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus 37565 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 37565 R-GGA-5620914 https://reactome.org/PathwayBrowser/#/R-GGA-5620914 ARF4:GTP binds VxPx-motifs of membrane proteins IEA Gallus gallus 37565 R-GGA-5620921 https://reactome.org/PathwayBrowser/#/R-GGA-5620921 ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex IEA Gallus gallus 37565 R-GGA-5623508 https://reactome.org/PathwayBrowser/#/R-GGA-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Gallus gallus 37565 R-GGA-5623513 https://reactome.org/PathwayBrowser/#/R-GGA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Gallus gallus 37565 R-GGA-5623519 https://reactome.org/PathwayBrowser/#/R-GGA-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Gallus gallus 37565 R-GGA-5623521 https://reactome.org/PathwayBrowser/#/R-GGA-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus 37565 R-GGA-5623524 https://reactome.org/PathwayBrowser/#/R-GGA-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Gallus gallus 37565 R-GGA-5623525 https://reactome.org/PathwayBrowser/#/R-GGA-5623525 Cargo-carrying vesicles bud from the TGN IEA Gallus gallus 37565 R-GGA-5623527 https://reactome.org/PathwayBrowser/#/R-GGA-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Gallus gallus 37565 R-GGA-5623622 https://reactome.org/PathwayBrowser/#/R-GGA-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Gallus gallus 37565 R-GGA-5623632 https://reactome.org/PathwayBrowser/#/R-GGA-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Gallus gallus 37565 R-GGA-5623667 https://reactome.org/PathwayBrowser/#/R-GGA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Gallus gallus 37565 R-GGA-5624126 https://reactome.org/PathwayBrowser/#/R-GGA-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Gallus gallus 37565 R-GGA-5624127 https://reactome.org/PathwayBrowser/#/R-GGA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Gallus gallus 37565 R-GGA-5624486 https://reactome.org/PathwayBrowser/#/R-GGA-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Gallus gallus 37565 R-GGA-5624492 https://reactome.org/PathwayBrowser/#/R-GGA-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Gallus gallus 37565 R-GGA-5624494 https://reactome.org/PathwayBrowser/#/R-GGA-5624494 RAF1 binds p21 RAS:GTP IEA Gallus gallus 37565 R-GGA-5625959 https://reactome.org/PathwayBrowser/#/R-GGA-5625959 Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) IEA Gallus gallus 37565 R-GGA-5626469 https://reactome.org/PathwayBrowser/#/R-GGA-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Gallus gallus 37565 R-GGA-5626507 https://reactome.org/PathwayBrowser/#/R-GGA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Gallus gallus 37565 R-GGA-5626549 https://reactome.org/PathwayBrowser/#/R-GGA-5626549 IQGAPs bind CALM1 IEA Gallus gallus 37565 R-GGA-5627071 https://reactome.org/PathwayBrowser/#/R-GGA-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane IEA Gallus gallus 37565 R-GGA-5627072 https://reactome.org/PathwayBrowser/#/R-GGA-5627072 RHOQ binds GOPC:CFTR IEA Gallus gallus 37565 R-GGA-5627775 https://reactome.org/PathwayBrowser/#/R-GGA-5627775 Autophosphorylation of PAK1,2,3 IEA Gallus gallus 37565 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus 37565 R-GGA-5638014 https://reactome.org/PathwayBrowser/#/R-GGA-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Gallus gallus 37565 R-GGA-5653957 https://reactome.org/PathwayBrowser/#/R-GGA-5653957 Rag dimer formation IEA Gallus gallus 37565 R-GGA-5653968 https://reactome.org/PathwayBrowser/#/R-GGA-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Gallus gallus 37565 R-GGA-5653974 https://reactome.org/PathwayBrowser/#/R-GGA-5653974 Ragulator binds Rag dimers IEA Gallus gallus 37565 R-GGA-5654392 https://reactome.org/PathwayBrowser/#/R-GGA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-5654402 https://reactome.org/PathwayBrowser/#/R-GGA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-5654413 https://reactome.org/PathwayBrowser/#/R-GGA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-5654426 https://reactome.org/PathwayBrowser/#/R-GGA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-5654600 https://reactome.org/PathwayBrowser/#/R-GGA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-5654618 https://reactome.org/PathwayBrowser/#/R-GGA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-5654647 https://reactome.org/PathwayBrowser/#/R-GGA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-5654663 https://reactome.org/PathwayBrowser/#/R-GGA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-5658231 https://reactome.org/PathwayBrowser/#/R-GGA-5658231 RAS GAPs stimulate RAS GTPase activity IEA Gallus gallus 37565 R-GGA-5658435 https://reactome.org/PathwayBrowser/#/R-GGA-5658435 RAS GAPs bind RAS:GTP IEA Gallus gallus 37565 R-GGA-5665727 https://reactome.org/PathwayBrowser/#/R-GGA-5665727 FMNL2 binds CDC42:GTP IEA Gallus gallus 37565 R-GGA-5665748 https://reactome.org/PathwayBrowser/#/R-GGA-5665748 FMNL2 binds RHOC:GTP IEA Gallus gallus 37565 R-GGA-5665761 https://reactome.org/PathwayBrowser/#/R-GGA-5665761 FMNL3 binds RHOC:GTP IEA Gallus gallus 37565 R-GGA-5665802 https://reactome.org/PathwayBrowser/#/R-GGA-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Gallus gallus 37565 R-GGA-5666070 https://reactome.org/PathwayBrowser/#/R-GGA-5666070 RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes IEA Gallus gallus 37565 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus 37565 R-GGA-5666216 https://reactome.org/PathwayBrowser/#/R-GGA-5666216 RHOA:GTP:RTKN binds TAX1BP3 IEA Gallus gallus 37565 R-GGA-5667008 https://reactome.org/PathwayBrowser/#/R-GGA-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Gallus gallus 37565 R-GGA-5668605 https://reactome.org/PathwayBrowser/#/R-GGA-5668605 RAC2:GTP binds NOX2 complex IEA Gallus gallus 37565 R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus 37565 R-GGA-5668714 https://reactome.org/PathwayBrowser/#/R-GGA-5668714 RAC1:GTP binds NOX1 complex IEA Gallus gallus 37565 R-GGA-5668718 https://reactome.org/PathwayBrowser/#/R-GGA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 37565 R-GGA-5668731 https://reactome.org/PathwayBrowser/#/R-GGA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 37565 R-GGA-5668735 https://reactome.org/PathwayBrowser/#/R-GGA-5668735 RAC1:GTP binds NOX3 complex IEA Gallus gallus 37565 R-GGA-5672010 https://reactome.org/PathwayBrowser/#/R-GGA-5672010 Active MTORC1 phosphorylates ULK1 IEA Gallus gallus 37565 R-GGA-5672017 https://reactome.org/PathwayBrowser/#/R-GGA-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Gallus gallus 37565 R-GGA-5672817 https://reactome.org/PathwayBrowser/#/R-GGA-5672817 Active MTORC1 binds the ULK1 complex IEA Gallus gallus 37565 R-GGA-5672824 https://reactome.org/PathwayBrowser/#/R-GGA-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Gallus gallus 37565 R-GGA-5672828 https://reactome.org/PathwayBrowser/#/R-GGA-5672828 mTORC1 phosphorylates AKT1S1 IEA Gallus gallus 37565 R-GGA-5672950 https://reactome.org/PathwayBrowser/#/R-GGA-5672950 "Activator" RAF:YWHAB dimer binds RAS:GTP IEA Gallus gallus 37565 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-5672966 https://reactome.org/PathwayBrowser/#/R-GGA-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Gallus gallus 37565 R-GGA-5672969 https://reactome.org/PathwayBrowser/#/R-GGA-5672969 Phosphorylation of RAF IEA Gallus gallus 37565 R-GGA-5672972 https://reactome.org/PathwayBrowser/#/R-GGA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Gallus gallus 37565 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 37565 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 37565 R-GGA-5672980 https://reactome.org/PathwayBrowser/#/R-GGA-5672980 Dissociation of RAS:RAF complex IEA Gallus gallus 37565 R-GGA-5673768 https://reactome.org/PathwayBrowser/#/R-GGA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Gallus gallus 37565 R-GGA-5674018 https://reactome.org/PathwayBrowser/#/R-GGA-5674018 BRAP binds RAS:GTP IEA Gallus gallus 37565 R-GGA-5674022 https://reactome.org/PathwayBrowser/#/R-GGA-5674022 BRAP autoubiquitinates IEA Gallus gallus 37565 R-GGA-5675417 https://reactome.org/PathwayBrowser/#/R-GGA-5675417 PEBP1 binds activated RAF1 IEA Gallus gallus 37565 R-GGA-5675790 https://reactome.org/PathwayBrowser/#/R-GGA-5675790 MTORC1 dissociates from ULK complex IEA Gallus gallus 37565 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus 37565 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus 37565 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus 37565 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus 37565 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus 37565 R-GGA-5696197 https://reactome.org/PathwayBrowser/#/R-GGA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Gallus gallus 37565 R-GGA-6787533 https://reactome.org/PathwayBrowser/#/R-GGA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Gallus gallus 37565 R-GGA-6788611 https://reactome.org/PathwayBrowser/#/R-GGA-6788611 HYKK phosphorylates 5HLYS IEA Gallus gallus 37565 R-GGA-6789092 https://reactome.org/PathwayBrowser/#/R-GGA-6789092 NOX2 generates superoxide anion from oxygen IEA Gallus gallus 37565 R-GGA-6807868 https://reactome.org/PathwayBrowser/#/R-GGA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Gallus gallus 37565 R-GGA-6807872 https://reactome.org/PathwayBrowser/#/R-GGA-6807872 Active ARF recruits coatomer IEA Gallus gallus 37565 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus 37565 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus 37565 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus 37565 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus 37565 R-GGA-6811417 https://reactome.org/PathwayBrowser/#/R-GGA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Gallus gallus 37565 R-GGA-6811418 https://reactome.org/PathwayBrowser/#/R-GGA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Gallus gallus 37565 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus 37565 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus 37565 R-GGA-6811429 https://reactome.org/PathwayBrowser/#/R-GGA-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Gallus gallus 37565 R-GGA-6811431 https://reactome.org/PathwayBrowser/#/R-GGA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Gallus gallus 37565 R-GGA-6814086 https://reactome.org/PathwayBrowser/#/R-GGA-6814086 ARFRP1 recruits ARL1 to the TGN IEA Gallus gallus 37565 R-GGA-6814088 https://reactome.org/PathwayBrowser/#/R-GGA-6814088 SYS1 binds AcM-ARFRP1 IEA Gallus gallus 37565 R-GGA-6814091 https://reactome.org/PathwayBrowser/#/R-GGA-6814091 ARL1 recruits TGN Golgin homodimers IEA Gallus gallus 37565 R-GGA-6814094 https://reactome.org/PathwayBrowser/#/R-GGA-6814094 ARL1:GTP binds ARFIP2 IEA Gallus gallus 37565 R-GGA-6814096 https://reactome.org/PathwayBrowser/#/R-GGA-6814096 ARL1:GTP binds SCOC IEA Gallus gallus 37565 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus 37565 R-GGA-6814670 https://reactome.org/PathwayBrowser/#/R-GGA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Gallus gallus 37565 R-GGA-6814671 https://reactome.org/PathwayBrowser/#/R-GGA-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Gallus gallus 37565 R-GGA-6814675 https://reactome.org/PathwayBrowser/#/R-GGA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Gallus gallus 37565 R-GGA-6814682 https://reactome.org/PathwayBrowser/#/R-GGA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Gallus gallus 37565 R-GGA-70241 https://reactome.org/PathwayBrowser/#/R-GGA-70241 PCK1 phosphorylates OA to yield PEP IEA Gallus gallus 37565 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Gallus gallus 37565 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Gallus gallus 37565 R-GGA-71775 https://reactome.org/PathwayBrowser/#/R-GGA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Gallus gallus 37565 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus 37565 R-GGA-72663 https://reactome.org/PathwayBrowser/#/R-GGA-72663 De novo formation of eIF2:GTP IEA Gallus gallus 37565 R-GGA-72669 https://reactome.org/PathwayBrowser/#/R-GGA-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Gallus gallus 37565 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus 37565 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus 37565 R-GGA-72691 https://reactome.org/PathwayBrowser/#/R-GGA-72691 Formation of the 43S pre-initiation complex IEA Gallus gallus 37565 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus 37565 R-GGA-72722 https://reactome.org/PathwayBrowser/#/R-GGA-72722 eIF2 activation IEA Gallus gallus 37565 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 37565 R-GGA-749453 https://reactome.org/PathwayBrowser/#/R-GGA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Gallus gallus 37565 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 37565 R-GGA-751019 https://reactome.org/PathwayBrowser/#/R-GGA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Gallus gallus 37565 R-GGA-751024 https://reactome.org/PathwayBrowser/#/R-GGA-751024 The Ligand:GPCR:Gz complex dissociates IEA Gallus gallus 37565 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus 37565 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus 37565 R-GGA-8847534 https://reactome.org/PathwayBrowser/#/R-GGA-8847534 RAB43 hydrolyses GTP IEA Gallus gallus 37565 R-GGA-8847537 https://reactome.org/PathwayBrowser/#/R-GGA-8847537 RAB43:GTP binds USP8NL IEA Gallus gallus 37565 R-GGA-8847887 https://reactome.org/PathwayBrowser/#/R-GGA-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Gallus gallus 37565 R-GGA-8848618 https://reactome.org/PathwayBrowser/#/R-GGA-8848618 Activation of RAC1 by the PXN:CRK complex IEA Gallus gallus 37565 R-GGA-8849082 https://reactome.org/PathwayBrowser/#/R-GGA-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Gallus gallus 37565 R-GGA-8849085 https://reactome.org/PathwayBrowser/#/R-GGA-8849085 ARHGAP35 binds RHOA:GTP IEA Gallus gallus 37565 R-GGA-8849348 https://reactome.org/PathwayBrowser/#/R-GGA-8849348 RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo IEA Gallus gallus 37565 R-GGA-8849350 https://reactome.org/PathwayBrowser/#/R-GGA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Gallus gallus 37565 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus 37565 R-GGA-8849748 https://reactome.org/PathwayBrowser/#/R-GGA-8849748 The COG complex binds RABs at the Golgi membrane IEA Gallus gallus 37565 R-GGA-8850041 https://reactome.org/PathwayBrowser/#/R-GGA-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Gallus gallus 37565 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 37565 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 37565 R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 37565 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 37565 R-GGA-8851827 https://reactome.org/PathwayBrowser/#/R-GGA-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Gallus gallus 37565 R-GGA-8851877 https://reactome.org/PathwayBrowser/#/R-GGA-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Gallus gallus 37565 R-GGA-8851899 https://reactome.org/PathwayBrowser/#/R-GGA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Gallus gallus 37565 R-GGA-8854173 https://reactome.org/PathwayBrowser/#/R-GGA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Gallus gallus 37565 R-GGA-8854293 https://reactome.org/PathwayBrowser/#/R-GGA-8854293 TBC1D10A (EPI64) binds ARF6:GTP IEA Gallus gallus 37565 R-GGA-8854303 https://reactome.org/PathwayBrowser/#/R-GGA-8854303 TBC1D11 binds RAB6 IEA Gallus gallus 37565 R-GGA-8854612 https://reactome.org/PathwayBrowser/#/R-GGA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Gallus gallus 37565 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus 37565 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus 37565 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus 37565 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus 37565 R-GGA-8875318 https://reactome.org/PathwayBrowser/#/R-GGA-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Gallus gallus 37565 R-GGA-8875320 https://reactome.org/PathwayBrowser/#/R-GGA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Gallus gallus 37565 R-GGA-8875568 https://reactome.org/PathwayBrowser/#/R-GGA-8875568 RAPGEF1 activates RAP1 IEA Gallus gallus 37565 R-GGA-8875591 https://reactome.org/PathwayBrowser/#/R-GGA-8875591 DOCK7 activates RAC1 IEA Gallus gallus 37565 R-GGA-8875659 https://reactome.org/PathwayBrowser/#/R-GGA-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Gallus gallus 37565 R-GGA-8875661 https://reactome.org/PathwayBrowser/#/R-GGA-8875661 GGA3 associates with activated MET receptor IEA Gallus gallus 37565 R-GGA-8876188 https://reactome.org/PathwayBrowser/#/R-GGA-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Gallus gallus 37565 R-GGA-8876190 https://reactome.org/PathwayBrowser/#/R-GGA-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Gallus gallus 37565 R-GGA-8876191 https://reactome.org/PathwayBrowser/#/R-GGA-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Gallus gallus 37565 R-GGA-8876193 https://reactome.org/PathwayBrowser/#/R-GGA-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Gallus gallus 37565 R-GGA-8876454 https://reactome.org/PathwayBrowser/#/R-GGA-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Gallus gallus 37565 R-GGA-8876616 https://reactome.org/PathwayBrowser/#/R-GGA-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Gallus gallus 37565 R-GGA-8876837 https://reactome.org/PathwayBrowser/#/R-GGA-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Gallus gallus 37565 R-GGA-8877308 https://reactome.org/PathwayBrowser/#/R-GGA-8877308 MADD exchanges GTP for GDP on RAB27 IEA Gallus gallus 37565 R-GGA-8877311 https://reactome.org/PathwayBrowser/#/R-GGA-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Gallus gallus 37565 R-GGA-8877451 https://reactome.org/PathwayBrowser/#/R-GGA-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Gallus gallus 37565 R-GGA-8877612 https://reactome.org/PathwayBrowser/#/R-GGA-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Gallus gallus 37565 R-GGA-8877760 https://reactome.org/PathwayBrowser/#/R-GGA-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Gallus gallus 37565 R-GGA-8877813 https://reactome.org/PathwayBrowser/#/R-GGA-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Gallus gallus 37565 R-GGA-8877998 https://reactome.org/PathwayBrowser/#/R-GGA-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Gallus gallus 37565 R-GGA-8941613 https://reactome.org/PathwayBrowser/#/R-GGA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-8941618 https://reactome.org/PathwayBrowser/#/R-GGA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-8941623 https://reactome.org/PathwayBrowser/#/R-GGA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-8941628 https://reactome.org/PathwayBrowser/#/R-GGA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 37565 R-GGA-8944454 https://reactome.org/PathwayBrowser/#/R-GGA-8944454 mTORC1 phosphorylates MAF1 IEA Gallus gallus 37565 R-GGA-8944457 https://reactome.org/PathwayBrowser/#/R-GGA-8944457 MAF1 translocates to the nucleus IEA Gallus gallus 37565 R-GGA-8951490 https://reactome.org/PathwayBrowser/#/R-GGA-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Gallus gallus 37565 R-GGA-8951498 https://reactome.org/PathwayBrowser/#/R-GGA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Gallus gallus 37565 R-GGA-8952716 https://reactome.org/PathwayBrowser/#/R-GGA-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Gallus gallus 37565 R-GGA-8952726 https://reactome.org/PathwayBrowser/#/R-GGA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Gallus gallus 37565 R-GGA-8964242 https://reactome.org/PathwayBrowser/#/R-GGA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Gallus gallus 37565 R-GGA-8964246 https://reactome.org/PathwayBrowser/#/R-GGA-8964246 BTK in G alpha (12)-BTK complex is activated IEA Gallus gallus 37565 R-GGA-8964274 https://reactome.org/PathwayBrowser/#/R-GGA-8964274 G alpha (12) binds BTK IEA Gallus gallus 37565 R-GGA-8964280 https://reactome.org/PathwayBrowser/#/R-GGA-8964280 Active Gq binds BTK IEA Gallus gallus 37565 R-GGA-8964284 https://reactome.org/PathwayBrowser/#/R-GGA-8964284 BTK in active Gq-BTK complex is activated IEA Gallus gallus 37565 R-GGA-8964329 https://reactome.org/PathwayBrowser/#/R-GGA-8964329 G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC IEA Gallus gallus 37565 R-GGA-8964333 https://reactome.org/PathwayBrowser/#/R-GGA-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) IEA Gallus gallus 37565 R-GGA-8964340 https://reactome.org/PathwayBrowser/#/R-GGA-8964340 Gq-BTK complex dissociates to Active BTK and Gq IEA Gallus gallus 37565 R-GGA-8964599 https://reactome.org/PathwayBrowser/#/R-GGA-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Gallus gallus 37565 R-GGA-8964604 https://reactome.org/PathwayBrowser/#/R-GGA-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Gallus gallus 37565 R-GGA-8964614 https://reactome.org/PathwayBrowser/#/R-GGA-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Gallus gallus 37565 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus 37565 R-GGA-8981353 https://reactome.org/PathwayBrowser/#/R-GGA-8981353 RASA1 stimulates RAS GTPase activity IEA Gallus gallus 37565 R-GGA-8981355 https://reactome.org/PathwayBrowser/#/R-GGA-8981355 RASA1 binds RAS:GTP IEA Gallus gallus 37565 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus 37565 R-GGA-8981892 https://reactome.org/PathwayBrowser/#/R-GGA-8981892 Active G alpha (z) binds RGS proteins IEA Gallus gallus 37565 R-GGA-8981926 https://reactome.org/PathwayBrowser/#/R-GGA-8981926 RAC1 and CDC42 activate PAK3 IEA Gallus gallus 37565 R-GGA-8981931 https://reactome.org/PathwayBrowser/#/R-GGA-8981931 RAC1 and CDC42 activate PAK2 IEA Gallus gallus 37565 R-GGA-8982017 https://reactome.org/PathwayBrowser/#/R-GGA-8982017 Active G alpha (q) binds RGS proteins IEA Gallus gallus 37565 R-GGA-8982019 https://reactome.org/PathwayBrowser/#/R-GGA-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Gallus gallus 37565 R-GGA-8982020 https://reactome.org/PathwayBrowser/#/R-GGA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Gallus gallus 37565 R-GGA-8982021 https://reactome.org/PathwayBrowser/#/R-GGA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Gallus gallus 37565 R-GGA-8982025 https://reactome.org/PathwayBrowser/#/R-GGA-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Gallus gallus 37565 R-GGA-8982640 https://reactome.org/PathwayBrowser/#/R-GGA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Gallus gallus 37565 R-GGA-8985594 https://reactome.org/PathwayBrowser/#/R-GGA-8985594 MYO9B inactivates RHOA IEA Gallus gallus 37565 R-GGA-9013004 https://reactome.org/PathwayBrowser/#/R-GGA-9013004 RHOA binds effectors at the ER membrane IEA Gallus gallus 37565 R-GGA-9013006 https://reactome.org/PathwayBrowser/#/R-GGA-9013006 RHOA:GTP translocates to the ER membrane IEA Gallus gallus 37565 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus 37565 R-GGA-9013023 https://reactome.org/PathwayBrowser/#/R-GGA-9013023 RHOB GEFs activate RHOB IEA Gallus gallus 37565 R-GGA-9013024 https://reactome.org/PathwayBrowser/#/R-GGA-9013024 RHOB binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9013109 https://reactome.org/PathwayBrowser/#/R-GGA-9013109 RHOC GEFs activate RHOC IEA Gallus gallus 37565 R-GGA-9013110 https://reactome.org/PathwayBrowser/#/R-GGA-9013110 RHOC binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus 37565 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus 37565 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus 37565 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus 37565 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus 37565 R-GGA-9013435 https://reactome.org/PathwayBrowser/#/R-GGA-9013435 RHOD auto-activates IEA Gallus gallus 37565 R-GGA-9013437 https://reactome.org/PathwayBrowser/#/R-GGA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Gallus gallus 37565 R-GGA-9013438 https://reactome.org/PathwayBrowser/#/R-GGA-9013438 RHOD binds effectors at the endosome membrane IEA Gallus gallus 37565 R-GGA-9013452 https://reactome.org/PathwayBrowser/#/R-GGA-9013452 RHOD:GTP translocates to the endosome membrane IEA Gallus gallus 37565 R-GGA-9014294 https://reactome.org/PathwayBrowser/#/R-GGA-9014294 RAC2 binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9014295 https://reactome.org/PathwayBrowser/#/R-GGA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Gallus gallus 37565 R-GGA-9014296 https://reactome.org/PathwayBrowser/#/R-GGA-9014296 RAC2 GEFs activate RAC2 IEA Gallus gallus 37565 R-GGA-9014420 https://reactome.org/PathwayBrowser/#/R-GGA-9014420 RAC2 translocates to the phagocytic vesicle membrane IEA Gallus gallus 37565 R-GGA-9014424 https://reactome.org/PathwayBrowser/#/R-GGA-9014424 RAC2 binds effectors at the phagocytic vesicle membrane IEA Gallus gallus 37565 R-GGA-9014433 https://reactome.org/PathwayBrowser/#/R-GGA-9014433 RHOG GEFs activate RHOG IEA Gallus gallus 37565 R-GGA-9014434 https://reactome.org/PathwayBrowser/#/R-GGA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Gallus gallus 37565 R-GGA-9014449 https://reactome.org/PathwayBrowser/#/R-GGA-9014449 RHOG binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9014454 https://reactome.org/PathwayBrowser/#/R-GGA-9014454 RHOG translocates to the ER membrane IEA Gallus gallus 37565 R-GGA-9014467 https://reactome.org/PathwayBrowser/#/R-GGA-9014467 RHOG binds effectors at the ER membrane IEA Gallus gallus 37565 R-GGA-9017488 https://reactome.org/PathwayBrowser/#/R-GGA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Gallus gallus 37565 R-GGA-9017491 https://reactome.org/PathwayBrowser/#/R-GGA-9017491 RHOJ GEFs activate RHOJ IEA Gallus gallus 37565 R-GGA-9018745 https://reactome.org/PathwayBrowser/#/R-GGA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Gallus gallus 37565 R-GGA-9018746 https://reactome.org/PathwayBrowser/#/R-GGA-9018746 RHOQ binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9018747 https://reactome.org/PathwayBrowser/#/R-GGA-9018747 RHOQ GEFs activate RHOQ IEA Gallus gallus 37565 R-GGA-9018754 https://reactome.org/PathwayBrowser/#/R-GGA-9018754 GDIs bind RHOH IEA Gallus gallus 37565 R-GGA-9018756 https://reactome.org/PathwayBrowser/#/R-GGA-9018756 RHOH binds GTP IEA Gallus gallus 37565 R-GGA-9018758 https://reactome.org/PathwayBrowser/#/R-GGA-9018758 RHOH binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9018766 https://reactome.org/PathwayBrowser/#/R-GGA-9018766 RHOU binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9018768 https://reactome.org/PathwayBrowser/#/R-GGA-9018768 RHOU auto-activates IEA Gallus gallus 37565 R-GGA-9018774 https://reactome.org/PathwayBrowser/#/R-GGA-9018774 RHOBTB1 binds GTP IEA Gallus gallus 37565 R-GGA-9018778 https://reactome.org/PathwayBrowser/#/R-GGA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Gallus gallus 37565 R-GGA-9018785 https://reactome.org/PathwayBrowser/#/R-GGA-9018785 RHOBTB2 binds GTP IEA Gallus gallus 37565 R-GGA-9018787 https://reactome.org/PathwayBrowser/#/R-GGA-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Gallus gallus 37565 R-GGA-9018794 https://reactome.org/PathwayBrowser/#/R-GGA-9018794 RHOV binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9018798 https://reactome.org/PathwayBrowser/#/R-GGA-9018798 RHOV binds GTP IEA Gallus gallus 37565 R-GGA-9018804 https://reactome.org/PathwayBrowser/#/R-GGA-9018804 RAC3 GEFs activate RAC3 IEA Gallus gallus 37565 R-GGA-9018806 https://reactome.org/PathwayBrowser/#/R-GGA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Gallus gallus 37565 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9018814 https://reactome.org/PathwayBrowser/#/R-GGA-9018814 RHOT1 hydrolyzes GTP IEA Gallus gallus 37565 R-GGA-9018815 https://reactome.org/PathwayBrowser/#/R-GGA-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Gallus gallus 37565 R-GGA-9018824 https://reactome.org/PathwayBrowser/#/R-GGA-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Gallus gallus 37565 R-GGA-9018826 https://reactome.org/PathwayBrowser/#/R-GGA-9018826 RHOT2 hydrolyzes GTP IEA Gallus gallus 37565 R-GGA-9018836 https://reactome.org/PathwayBrowser/#/R-GGA-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Gallus gallus 37565 R-GGA-9032798 https://reactome.org/PathwayBrowser/#/R-GGA-9032798 DOCK3 activates RAC1 IEA Gallus gallus 37565 R-GGA-9036301 https://reactome.org/PathwayBrowser/#/R-GGA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Gallus gallus 37565 R-GGA-939265 https://reactome.org/PathwayBrowser/#/R-GGA-939265 Activation of Rap1 by membrane-associated GEFs IEA Gallus gallus 37565 R-GGA-947535 https://reactome.org/PathwayBrowser/#/R-GGA-947535 Cyclisation of GTP to precursor Z IEA Gallus gallus 37565 R-GGA-9607304 https://reactome.org/PathwayBrowser/#/R-GGA-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Gallus gallus 37565 R-GGA-9610152 https://reactome.org/PathwayBrowser/#/R-GGA-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Gallus gallus 37565 R-GGA-9610153 https://reactome.org/PathwayBrowser/#/R-GGA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Gallus gallus 37565 R-GGA-9610154 https://reactome.org/PathwayBrowser/#/R-GGA-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Gallus gallus 37565 R-GGA-9610156 https://reactome.org/PathwayBrowser/#/R-GGA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Gallus gallus 37565 R-GGA-9610163 https://reactome.org/PathwayBrowser/#/R-GGA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Gallus gallus 37565 R-GGA-9624845 https://reactome.org/PathwayBrowser/#/R-GGA-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Gallus gallus 37565 R-GGA-9624876 https://reactome.org/PathwayBrowser/#/R-GGA-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Gallus gallus 37565 R-GGA-9624893 https://reactome.org/PathwayBrowser/#/R-GGA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Gallus gallus 37565 R-GGA-9626848 https://reactome.org/PathwayBrowser/#/R-GGA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Gallus gallus 37565 R-GGA-9632910 https://reactome.org/PathwayBrowser/#/R-GGA-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Gallus gallus 37565 R-GGA-9632918 https://reactome.org/PathwayBrowser/#/R-GGA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Gallus gallus 37565 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus 37565 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus 37565 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus 37565 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus 37565 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus 37565 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus 37565 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus 37565 R-GGA-9646679 https://reactome.org/PathwayBrowser/#/R-GGA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Gallus gallus 37565 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus 37565 R-GGA-9649735 https://reactome.org/PathwayBrowser/#/R-GGA-9649735 Intrinsic nucleotide exchange on RAS IEA Gallus gallus 37565 R-GGA-9649736 https://reactome.org/PathwayBrowser/#/R-GGA-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Gallus gallus 37565 R-GGA-9653108 https://reactome.org/PathwayBrowser/#/R-GGA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Gallus gallus 37565 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus 37565 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus 37565 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 37565 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus 37565 R-GGA-9658253 https://reactome.org/PathwayBrowser/#/R-GGA-9658253 RAS:GTP binds PI3K IEA Gallus gallus 37565 R-GGA-9658445 https://reactome.org/PathwayBrowser/#/R-GGA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Gallus gallus 37565 R-GGA-9660557 https://reactome.org/PathwayBrowser/#/R-GGA-9660557 RAS:GTP binds RAL GDS proteins IEA Gallus gallus 37565 R-GGA-9690493 https://reactome.org/PathwayBrowser/#/R-GGA-9690493 RHOB binds effectors on endosomes IEA Gallus gallus 37565 R-GGA-9690494 https://reactome.org/PathwayBrowser/#/R-GGA-9690494 RHOB translocates to the endosome membrane IEA Gallus gallus 37565 R-GGA-9691168 https://reactome.org/PathwayBrowser/#/R-GGA-9691168 RAC1 translocates to the endoplasmic reticulum membrane IEA Gallus gallus 37565 R-GGA-9691174 https://reactome.org/PathwayBrowser/#/R-GGA-9691174 RAC1 binds effectors at the ER membrane IEA Gallus gallus 37565 R-GGA-9692800 https://reactome.org/PathwayBrowser/#/R-GGA-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Gallus gallus 37565 R-GGA-9692809 https://reactome.org/PathwayBrowser/#/R-GGA-9692809 CDC42 binds effectors at the ER membrane IEA Gallus gallus 37565 R-GGA-9693111 https://reactome.org/PathwayBrowser/#/R-GGA-9693111 RHOF auto-activates IEA Gallus gallus 37565 R-GGA-9693125 https://reactome.org/PathwayBrowser/#/R-GGA-9693125 RHOF binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9693198 https://reactome.org/PathwayBrowser/#/R-GGA-9693198 RHOD binds effectors at the plasma membrane IEA Gallus gallus 37565 R-GGA-9693207 https://reactome.org/PathwayBrowser/#/R-GGA-9693207 RHOD translocates to the mitochondrial outer membrane IEA Gallus gallus 37565 R-GGA-9693214 https://reactome.org/PathwayBrowser/#/R-GGA-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Gallus gallus 37565 R-GGA-9693243 https://reactome.org/PathwayBrowser/#/R-GGA-9693243 RHOD translocates to the Golgi membrane IEA Gallus gallus 37565 R-GGA-9693250 https://reactome.org/PathwayBrowser/#/R-GGA-9693250 RHOD binds effectors at the Golgi membrane IEA Gallus gallus 37565 R-GGA-9693282 https://reactome.org/PathwayBrowser/#/R-GGA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Gallus gallus 37565 R-GGA-9696266 https://reactome.org/PathwayBrowser/#/R-GGA-9696266 RND2 binds effectors IEA Gallus gallus 37565 R-GGA-9696267 https://reactome.org/PathwayBrowser/#/R-GGA-9696267 RND3 binds GTP IEA Gallus gallus 37565 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus 37565 R-GGA-9696271 https://reactome.org/PathwayBrowser/#/R-GGA-9696271 RND1 binds effectors IEA Gallus gallus 37565 R-GGA-9696274 https://reactome.org/PathwayBrowser/#/R-GGA-9696274 RND1 binds GTP IEA Gallus gallus 37565 R-GGA-9696275 https://reactome.org/PathwayBrowser/#/R-GGA-9696275 RND2 binds GTP IEA Gallus gallus 37565 R-GGA-9714361 https://reactome.org/PathwayBrowser/#/R-GGA-9714361 RHOC activates endoplasmic reticulum effectors IEA Gallus gallus 37565 R-GGA-9714363 https://reactome.org/PathwayBrowser/#/R-GGA-9714363 RHOC translocates to the endoplasmic reticulum membrane IEA Gallus gallus 37565 R-GGA-9714477 https://reactome.org/PathwayBrowser/#/R-GGA-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Gallus gallus 37565 R-GGA-9714480 https://reactome.org/PathwayBrowser/#/R-GGA-9714480 RAC2 translocates to the mitochondrial membrane IEA Gallus gallus 37565 R-GGA-9714483 https://reactome.org/PathwayBrowser/#/R-GGA-9714483 RAC2 translocates to the ER membrane IEA Gallus gallus 37565 R-GGA-9714694 https://reactome.org/PathwayBrowser/#/R-GGA-9714694 RAC3 translocates to the endoplasmic reticulum membrane IEA Gallus gallus 37565 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus 37565 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus 37565 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus 37565 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus 37565 R-HSA-1008248 https://reactome.org/PathwayBrowser/#/R-HSA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase TAS Homo sapiens 37565 R-HSA-109807 https://reactome.org/PathwayBrowser/#/R-HSA-109807 GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS IEA Homo sapiens 37565 R-HSA-109817 https://reactome.org/PathwayBrowser/#/R-HSA-109817 GRB2:SOS1:p-Y-IRS1,p-Y-IRS2 mediated nucleotide exchange of RAS IEA Homo sapiens 37565 R-HSA-111524 https://reactome.org/PathwayBrowser/#/R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] TAS Homo sapiens 37565 R-HSA-111870 https://reactome.org/PathwayBrowser/#/R-HSA-111870 Activation of PLC beta-1/4 IEA Homo sapiens 37565 R-HSA-111879 https://reactome.org/PathwayBrowser/#/R-HSA-111879 PIP2 hydrolysis TAS Homo sapiens 37565 R-HSA-112037 https://reactome.org/PathwayBrowser/#/R-HSA-112037 Inactivation of PLC beta TAS Homo sapiens 37565 R-HSA-112271 https://reactome.org/PathwayBrowser/#/R-HSA-112271 The receptor:G-protein complex dissociates TAS Homo sapiens 37565 R-HSA-114542 https://reactome.org/PathwayBrowser/#/R-HSA-114542 RAC1,RAC2,RHOG activate PI3K TAS Homo sapiens 37565 R-HSA-114544 https://reactome.org/PathwayBrowser/#/R-HSA-114544 p115-RhoGEF activation of RHOA TAS Homo sapiens 37565 R-HSA-114548 https://reactome.org/PathwayBrowser/#/R-HSA-114548 G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) TAS Homo sapiens 37565 R-HSA-114552 https://reactome.org/PathwayBrowser/#/R-HSA-114552 Thrombin-activated PARs activate G12/13 TAS Homo sapiens 37565 R-HSA-114558 https://reactome.org/PathwayBrowser/#/R-HSA-114558 Thrombin-activated PARs activate Gq TAS Homo sapiens 37565 R-HSA-114688 https://reactome.org/PathwayBrowser/#/R-HSA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 TAS Homo sapiens 37565 R-HSA-1168636 https://reactome.org/PathwayBrowser/#/R-HSA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP TAS Homo sapiens 37565 R-HSA-1225951 https://reactome.org/PathwayBrowser/#/R-HSA-1225951 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants) TAS Homo sapiens 37565 R-HSA-1225957 https://reactome.org/PathwayBrowser/#/R-HSA-1225957 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and ligand-responsive p-6Y-EGFR mutants) TAS Homo sapiens 37565 R-HSA-1250383 https://reactome.org/PathwayBrowser/#/R-HSA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 TAS Homo sapiens 37565 R-HSA-1250463 https://reactome.org/PathwayBrowser/#/R-HSA-1250463 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-SHC1:Phosphorylated ERBB2 heterodimers IEA Homo sapiens 37565 R-HSA-1250498 https://reactome.org/PathwayBrowser/#/R-HSA-1250498 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and phosphorylated EGFR:ERBB2 heterodimers. IEA Homo sapiens 37565 R-HSA-1306972 https://reactome.org/PathwayBrowser/#/R-HSA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers TAS Homo sapiens 37565 R-HSA-141673 https://reactome.org/PathwayBrowser/#/R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex IEA Homo sapiens 37565 R-HSA-141691 https://reactome.org/PathwayBrowser/#/R-HSA-141691 GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex IEA Homo sapiens 37565 R-HSA-1433415 https://reactome.org/PathwayBrowser/#/R-HSA-1433415 Activation of RAC1 TAS Homo sapiens 37565 R-HSA-1433471 https://reactome.org/PathwayBrowser/#/R-HSA-1433471 Activation of RAS by p-KIT bound SOS1 TAS Homo sapiens 37565 R-HSA-1445143 https://reactome.org/PathwayBrowser/#/R-HSA-1445143 RAB8A,10,13,14 hydrolyze GTP IEA Homo sapiens 37565 R-HSA-1474146 https://reactome.org/PathwayBrowser/#/R-HSA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate TAS Homo sapiens 37565 R-HSA-156808 https://reactome.org/PathwayBrowser/#/R-HSA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation TAS Homo sapiens 37565 R-HSA-156823 https://reactome.org/PathwayBrowser/#/R-HSA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA TAS Homo sapiens 37565 R-HSA-156907 https://reactome.org/PathwayBrowser/#/R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site IEA Homo sapiens 37565 R-HSA-156908 https://reactome.org/PathwayBrowser/#/R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. TAS Homo sapiens 37565 R-HSA-156909 https://reactome.org/PathwayBrowser/#/R-HSA-156909 eEF1A complexes with GTP IEA Homo sapiens 37565 R-HSA-156913 https://reactome.org/PathwayBrowser/#/R-HSA-156913 Regeneration of eEF1A:GTP by eEF1B activity TAS Homo sapiens 37565 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 37565 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 37565 R-HSA-156930 https://reactome.org/PathwayBrowser/#/R-HSA-156930 GTP-binding activates eEF2 TAS Homo sapiens 37565 R-HSA-157849 https://reactome.org/PathwayBrowser/#/R-HSA-157849 Formation of translation initiation complexes containing mRNA that does not circularize TAS Homo sapiens 37565 R-HSA-163617 https://reactome.org/PathwayBrowser/#/R-HSA-163617 G alpha (s) activates adenylate cyclase TAS Homo sapiens 37565 R-HSA-1638803 https://reactome.org/PathwayBrowser/#/R-HSA-1638803 Phosphorylation of cohesin by PLK1 at centromeres TAS Homo sapiens 37565 R-HSA-1638821 https://reactome.org/PathwayBrowser/#/R-HSA-1638821 PP2A-B56 dephosphorylates centromeric cohesin TAS Homo sapiens 37565 R-HSA-164377 https://reactome.org/PathwayBrowser/#/R-HSA-164377 Activated Adenylate cyclase catalyses cAMP synthesis TAS Homo sapiens 37565 R-HSA-164381 https://reactome.org/PathwayBrowser/#/R-HSA-164381 G alpha (s) auto-inactivates by hydrolysing GTP to GDP TAS Homo sapiens 37565 R-HSA-165028 https://reactome.org/PathwayBrowser/#/R-HSA-165028 Release of the HIV mRNA and Crm1 from Rev in the cytoplasm TAS Homo sapiens 37565 R-HSA-165034 https://reactome.org/PathwayBrowser/#/R-HSA-165034 Rev multimer-bound HIV mRNA:CRM1 complex associates with Ran:GTP TAS Homo sapiens 37565 R-HSA-165043 https://reactome.org/PathwayBrowser/#/R-HSA-165043 Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC TAS Homo sapiens 37565 R-HSA-165047 https://reactome.org/PathwayBrowser/#/R-HSA-165047 Translocation of nuclear RNA transport complex to cytoplasm TAS Homo sapiens 37565 R-HSA-165055 https://reactome.org/PathwayBrowser/#/R-HSA-165055 Hydrolysis of Ran:GTP to Ran:GDP TAS Homo sapiens 37565 R-HSA-165195 https://reactome.org/PathwayBrowser/#/R-HSA-165195 GTP loading by Rheb TAS Homo sapiens 37565 R-HSA-1655825 https://reactome.org/PathwayBrowser/#/R-HSA-1655825 SREBP1A,1C,2:SCAP binds CopII Coat Complex IEA Homo sapiens 37565 R-HSA-1655834 https://reactome.org/PathwayBrowser/#/R-HSA-1655834 SREBP1A,1C,2:SCAP translocates to the Golgi IEA Homo sapiens 37565 R-HSA-165680 https://reactome.org/PathwayBrowser/#/R-HSA-165680 Formation of active mTORC1 complex TAS Homo sapiens 37565 R-HSA-165692 https://reactome.org/PathwayBrowser/#/R-HSA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 TAS Homo sapiens 37565 R-HSA-165718 https://reactome.org/PathwayBrowser/#/R-HSA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) TAS Homo sapiens 37565 R-HSA-167415 https://reactome.org/PathwayBrowser/#/R-HSA-167415 G-protein alpha subunit is inactivated TAS Homo sapiens 37565 R-HSA-167429 https://reactome.org/PathwayBrowser/#/R-HSA-167429 The receptor:G-protein complex binds GTP TAS Homo sapiens 37565 R-HSA-168880 https://reactome.org/PathwayBrowser/#/R-HSA-168880 vRNP Export through the nuclear pore TAS Homo sapiens 37565 R-HSA-169901 https://reactome.org/PathwayBrowser/#/R-HSA-169901 Rap1-GTP complex binds BRAF complex IEA Homo sapiens 37565 R-HSA-169904 https://reactome.org/PathwayBrowser/#/R-HSA-169904 C3G stimulates nucleotide exchange on Rap1 TAS Homo sapiens 37565 R-HSA-170026 https://reactome.org/PathwayBrowser/#/R-HSA-170026 Protons are translocated from the intermembrane space to the matrix TAS Homo sapiens 37565 R-HSA-170666 https://reactome.org/PathwayBrowser/#/R-HSA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf TAS Homo sapiens 37565 R-HSA-170671 https://reactome.org/PathwayBrowser/#/R-HSA-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex TAS Homo sapiens 37565 R-HSA-170672 https://reactome.org/PathwayBrowser/#/R-HSA-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it TAS Homo sapiens 37565 R-HSA-170676 https://reactome.org/PathwayBrowser/#/R-HSA-170676 Adenylate cyclase converts ATP into cyclic AMP TAS Homo sapiens 37565 R-HSA-170685 https://reactome.org/PathwayBrowser/#/R-HSA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf TAS Homo sapiens 37565 R-HSA-170686 https://reactome.org/PathwayBrowser/#/R-HSA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha TAS Homo sapiens 37565 R-HSA-170965 https://reactome.org/PathwayBrowser/#/R-HSA-170965 (Frs2)Rap1-GTP binds to and activates B-Raf IEA Homo sapiens 37565 R-HSA-170979 https://reactome.org/PathwayBrowser/#/R-HSA-170979 (Frs2)C3G stimulates nucleotide exchange on Rap1 IEA Homo sapiens 37565 R-HSA-170986 https://reactome.org/PathwayBrowser/#/R-HSA-170986 Ral-GDS binds to Ras-GTP TAS Homo sapiens 37565 R-HSA-170991 https://reactome.org/PathwayBrowser/#/R-HSA-170991 SRC-1 autophosphorylates IEA Homo sapiens 37565 R-HSA-171026 https://reactome.org/PathwayBrowser/#/R-HSA-171026 Guanine nucleotide exchange on RAL IEA Homo sapiens 37565 R-HSA-177501 https://reactome.org/PathwayBrowser/#/R-HSA-177501 Endocytosis (internalization) of clathrin-coated vesicle IEA Homo sapiens 37565 R-HSA-177938 https://reactome.org/PathwayBrowser/#/R-HSA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) TAS Homo sapiens 37565 R-HSA-177945 https://reactome.org/PathwayBrowser/#/R-HSA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) TAS Homo sapiens 37565 R-HSA-180687 https://reactome.org/PathwayBrowser/#/R-HSA-180687 Conversion of Ran-GDP to Ran-GTP TAS Homo sapiens 37565 R-HSA-180728 https://reactome.org/PathwayBrowser/#/R-HSA-180728 Association of Ran-GTP with importin-beta TAS Homo sapiens 37565 R-HSA-180736 https://reactome.org/PathwayBrowser/#/R-HSA-180736 Disassembly of the Rev-importin beta-B23:Ran-GTP complex TAS Homo sapiens 37565 R-HSA-180739 https://reactome.org/PathwayBrowser/#/R-HSA-180739 Association of RanBP1 with Ran-GTP:CRM1:Rev:mRNA complex TAS Homo sapiens 37565 R-HSA-183002 https://reactome.org/PathwayBrowser/#/R-HSA-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 TAS Homo sapiens 37565 R-HSA-183084 https://reactome.org/PathwayBrowser/#/R-HSA-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix TAS Homo sapiens 37565 R-HSA-183094 https://reactome.org/PathwayBrowser/#/R-HSA-183094 CDC42:GTP binds CBL:Beta-Pix TAS Homo sapiens 37565 R-HSA-186834 https://reactome.org/PathwayBrowser/#/R-HSA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) TAS Homo sapiens 37565 R-HSA-187698 https://reactome.org/PathwayBrowser/#/R-HSA-187698 RIT/RIN-GTP binds B-RAF IEA Homo sapiens 37565 R-HSA-187746 https://reactome.org/PathwayBrowser/#/R-HSA-187746 RIT/RIN are activated IEA Homo sapiens 37565 R-HSA-190520 https://reactome.org/PathwayBrowser/#/R-HSA-190520 Association of Golgi transport vesicles with microtubules TAS Homo sapiens 37565 R-HSA-190877 https://reactome.org/PathwayBrowser/#/R-HSA-190877 Insertion of connexons into the plasma membrane resulting in the formation of hemi-channels IEA Homo sapiens 37565 R-HSA-191737 https://reactome.org/PathwayBrowser/#/R-HSA-191737 Docking of connexons into junctional, double-membrane spanning channels IEA Homo sapiens 37565 R-HSA-194518 https://reactome.org/PathwayBrowser/#/R-HSA-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth TAS Homo sapiens 37565 R-HSA-2029445 https://reactome.org/PathwayBrowser/#/R-HSA-2029445 An unknown GEF exchanges GTP for GDP on CDC42:GDP TAS Homo sapiens 37565 R-HSA-2029451 https://reactome.org/PathwayBrowser/#/R-HSA-2029451 Activation of RAC1 by VAV TAS Homo sapiens 37565 R-HSA-2029454 https://reactome.org/PathwayBrowser/#/R-HSA-2029454 Autophosphorylation of PAK1 TAS Homo sapiens 37565 R-HSA-2029456 https://reactome.org/PathwayBrowser/#/R-HSA-2029456 RAC1 and CDC42 activate PAK1 TAS Homo sapiens 37565 R-HSA-2029465 https://reactome.org/PathwayBrowser/#/R-HSA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) TAS Homo sapiens 37565 R-HSA-2029466 https://reactome.org/PathwayBrowser/#/R-HSA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin TAS Homo sapiens 37565 R-HSA-2029467 https://reactome.org/PathwayBrowser/#/R-HSA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO TAS Homo sapiens 37565 R-HSA-2029469 https://reactome.org/PathwayBrowser/#/R-HSA-2029469 p-ERK phosphorylates WAVEs and ABI TAS Homo sapiens 37565 R-HSA-203906 https://reactome.org/PathwayBrowser/#/R-HSA-203906 Exportin complex translocates pre-miRNA to cytosol TAS Homo sapiens 37565 R-HSA-203922 https://reactome.org/PathwayBrowser/#/R-HSA-203922 Exportin-5 recognizes 3' overhang of pre-miRNA TAS Homo sapiens 37565 R-HSA-203973 https://reactome.org/PathwayBrowser/#/R-HSA-203973 Vesicle budding TAS Homo sapiens 37565 R-HSA-203977 https://reactome.org/PathwayBrowser/#/R-HSA-203977 SAR1 Activation And Membrane Binding TAS Homo sapiens 37565 R-HSA-203979 https://reactome.org/PathwayBrowser/#/R-HSA-203979 Coat Assembly TAS Homo sapiens 37565 R-HSA-204008 https://reactome.org/PathwayBrowser/#/R-HSA-204008 SEC31:SEC13 and v-SNARE recruitment TAS Homo sapiens 37565 R-HSA-205039 https://reactome.org/PathwayBrowser/#/R-HSA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor TAS Homo sapiens 37565 R-HSA-205136 https://reactome.org/PathwayBrowser/#/R-HSA-205136 GTP-bound RAC contributes to JNK activation TAS Homo sapiens 37565 R-HSA-2065539 https://reactome.org/PathwayBrowser/#/R-HSA-2065539 SREBP1A,1C,2:Importin beta-1 dissociates TAS Homo sapiens 37565 R-HSA-210977 https://reactome.org/PathwayBrowser/#/R-HSA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) TAS Homo sapiens 37565 R-HSA-2130194 https://reactome.org/PathwayBrowser/#/R-HSA-2130194 ABL phosphorylates WAVEs TAS Homo sapiens 37565 R-HSA-2130619 https://reactome.org/PathwayBrowser/#/R-HSA-2130619 TGN-lysosomal vesicle coat assembly TAS Homo sapiens 37565 R-HSA-2130641 https://reactome.org/PathwayBrowser/#/R-HSA-2130641 Translocation of TGN-lysosome vesicle to lysosome TAS Homo sapiens 37565 R-HSA-2130725 https://reactome.org/PathwayBrowser/#/R-HSA-2130725 Internalization of MHC II:Ii clathrin coated vesicle TAS Homo sapiens 37565 R-HSA-2130731 https://reactome.org/PathwayBrowser/#/R-HSA-2130731 Formation of COPII vesicle TAS Homo sapiens 37565 R-HSA-2134506 https://reactome.org/PathwayBrowser/#/R-HSA-2134506 TGFBR1 is recruited to tight junctions by PARD6A IEA Homo sapiens 37565 R-HSA-2134519 https://reactome.org/PathwayBrowser/#/R-HSA-2134519 TGFBR2 is recruited to tight junctions after TGF-beta stimulation IEA Homo sapiens 37565 R-HSA-2134532 https://reactome.org/PathwayBrowser/#/R-HSA-2134532 TGFBR2 phosphorylates TGFBR1 and PARD6A IEA Homo sapiens 37565 R-HSA-2172183 https://reactome.org/PathwayBrowser/#/R-HSA-2172183 Phosphorylation of GORASP1, GOLGA2 and RAB1A by CDK1:CCNB IEA Homo sapiens 37565 R-HSA-2172194 https://reactome.org/PathwayBrowser/#/R-HSA-2172194 Recruitment of PLK1 to phosphorylated GORASP1 (GRASP65) IEA Homo sapiens 37565 R-HSA-2179407 https://reactome.org/PathwayBrowser/#/R-HSA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) TAS Homo sapiens 37565 R-HSA-2197690 https://reactome.org/PathwayBrowser/#/R-HSA-2197690 Detachment of WASP/WAVE TAS Homo sapiens 37565 R-HSA-2197691 https://reactome.org/PathwayBrowser/#/R-HSA-2197691 WIP binds WASP,N-WASP, activating them TAS Homo sapiens 37565 R-HSA-2197698 https://reactome.org/PathwayBrowser/#/R-HSA-2197698 Src phosphorylate WASP,N-WASP TAS Homo sapiens 37565 R-HSA-2213243 https://reactome.org/PathwayBrowser/#/R-HSA-2213243 Fusion of COPII vesicle with Golgi complex TAS Homo sapiens 37565 R-HSA-2213248 https://reactome.org/PathwayBrowser/#/R-HSA-2213248 Transport of antigen loaded MHC II molecules to surface TAS Homo sapiens 37565 R-HSA-2214351 https://reactome.org/PathwayBrowser/#/R-HSA-2214351 PLK1 phosphorylates GORASP1 TAS Homo sapiens 37565 R-HSA-2255343 https://reactome.org/PathwayBrowser/#/R-HSA-2255343 RAB8A,10,13,14 exchange GDP for GTP IEA Homo sapiens 37565 R-HSA-2314566 https://reactome.org/PathwayBrowser/#/R-HSA-2314566 GORASP1 phosphorylated by PLK1 and GORASP2 phosphorylated by MAPK3-3/MAPK1 are unable to promote Golgi cisternae stacking TAS Homo sapiens 37565 R-HSA-2314569 https://reactome.org/PathwayBrowser/#/R-HSA-2314569 GOLGA2 phosphorylated by CDK1 is unable to promote fusion of ER to Golgi transport vesicles with cis-Golgi TAS Homo sapiens 37565 R-HSA-2316347 https://reactome.org/PathwayBrowser/#/R-HSA-2316347 RAB4A:GTP binds KIF3 and activates KIF3 IEA Homo sapiens 37565 R-HSA-2316352 https://reactome.org/PathwayBrowser/#/R-HSA-2316352 SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane IEA Homo sapiens 37565 R-HSA-2316434 https://reactome.org/PathwayBrowser/#/R-HSA-2316434 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 37565 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 37565 R-HSA-2408509 https://reactome.org/PathwayBrowser/#/R-HSA-2408509 Sec-tRNA(Sec) binds to EEFSEC:GTP IEA Homo sapiens 37565 R-HSA-2408529 https://reactome.org/PathwayBrowser/#/R-HSA-2408529 Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome IEA Homo sapiens 37565 R-HSA-2422927 https://reactome.org/PathwayBrowser/#/R-HSA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 TAS Homo sapiens 37565 R-HSA-2424476 https://reactome.org/PathwayBrowser/#/R-HSA-2424476 Activation of RAC1 by VAV2/3 TAS Homo sapiens 37565 R-HSA-2424477 https://reactome.org/PathwayBrowser/#/R-HSA-2424477 SOS mediated nucleotide exchange of RAS (SHC) TAS Homo sapiens 37565 R-HSA-2467809 https://reactome.org/PathwayBrowser/#/R-HSA-2467809 ESPL1 (Separase) cleaves centromeric cohesin TAS Homo sapiens 37565 R-HSA-2467811 https://reactome.org/PathwayBrowser/#/R-HSA-2467811 Separation of sister chromatids TAS Homo sapiens 37565 R-HSA-2468287 https://reactome.org/PathwayBrowser/#/R-HSA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres TAS Homo sapiens 37565 R-HSA-2484822 https://reactome.org/PathwayBrowser/#/R-HSA-2484822 Kinetochore assembly TAS Homo sapiens 37565 R-HSA-2485180 https://reactome.org/PathwayBrowser/#/R-HSA-2485180 MII catalyses GDP/GTP exchange on Gt IEA Homo sapiens 37565 R-HSA-2485182 https://reactome.org/PathwayBrowser/#/R-HSA-2485182 Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 TAS Homo sapiens 37565 R-HSA-2562526 https://reactome.org/PathwayBrowser/#/R-HSA-2562526 PLK1 phosphorylates OPTN TAS Homo sapiens 37565 R-HSA-2584246 https://reactome.org/PathwayBrowser/#/R-HSA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP TAS Homo sapiens 37565 R-HSA-265166 https://reactome.org/PathwayBrowser/#/R-HSA-265166 Exocytosis of Insulin IEA Homo sapiens 37565 R-HSA-2730840 https://reactome.org/PathwayBrowser/#/R-HSA-2730840 Activation of RAC1 by VAV TAS Homo sapiens 37565 R-HSA-2730856 https://reactome.org/PathwayBrowser/#/R-HSA-2730856 Autophosphorylation of PAK TAS Homo sapiens 37565 R-HSA-2730889 https://reactome.org/PathwayBrowser/#/R-HSA-2730889 Recruitment of PAK to the membrane by binding active RAC1 TAS Homo sapiens 37565 R-HSA-3244614 https://reactome.org/PathwayBrowser/#/R-HSA-3244614 cGAS produces cyclic GMP-AMP TAS Homo sapiens 37565 R-HSA-350769 https://reactome.org/PathwayBrowser/#/R-HSA-350769 trans-Golgi Network Coat Activation TAS Homo sapiens 37565 R-HSA-354060 https://reactome.org/PathwayBrowser/#/R-HSA-354060 Translocation of RIAM to plasma membrane TAS Homo sapiens 37565 R-HSA-354066 https://reactome.org/PathwayBrowser/#/R-HSA-354066 Translocation of PTK2 to Focal complexes TAS Homo sapiens 37565 R-HSA-354073 https://reactome.org/PathwayBrowser/#/R-HSA-354073 Autophosphorylation of PTK2 at Y397 TAS Homo sapiens 37565 R-HSA-354077 https://reactome.org/PathwayBrowser/#/R-HSA-354077 Integrin alphaIIb beta3 activation TAS Homo sapiens 37565 R-HSA-354087 https://reactome.org/PathwayBrowser/#/R-HSA-354087 Recruitment of GRB2 to p-PTK2 TAS Homo sapiens 37565 R-HSA-354097 https://reactome.org/PathwayBrowser/#/R-HSA-354097 Activation of Talin TAS Homo sapiens 37565 R-HSA-354124 https://reactome.org/PathwayBrowser/#/R-HSA-354124 Phosphorylation of pPTK2 by SRC TAS Homo sapiens 37565 R-HSA-354149 https://reactome.org/PathwayBrowser/#/R-HSA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen TAS Homo sapiens 37565 R-HSA-354165 https://reactome.org/PathwayBrowser/#/R-HSA-354165 Interaction of SOS with GRB2 bound to FADK1 TAS Homo sapiens 37565 R-HSA-354173 https://reactome.org/PathwayBrowser/#/R-HSA-354173 Activation of Rap1 by cytosolic GEFs TAS Homo sapiens 37565 R-HSA-372693 https://reactome.org/PathwayBrowser/#/R-HSA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex TAS Homo sapiens 37565 R-HSA-372697 https://reactome.org/PathwayBrowser/#/R-HSA-372697 Crk binding to p130cas TAS Homo sapiens 37565 R-HSA-372705 https://reactome.org/PathwayBrowser/#/R-HSA-372705 Recruitment of BCAR1 to PTK2 complex TAS Homo sapiens 37565 R-HSA-372819 https://reactome.org/PathwayBrowser/#/R-HSA-372819 PCK2 phosphorylates OA to yield PEP TAS Homo sapiens 37565 R-HSA-375302 https://reactome.org/PathwayBrowser/#/R-HSA-375302 Kinetochore capture of astral microtubules TAS Homo sapiens 37565 R-HSA-376117 https://reactome.org/PathwayBrowser/#/R-HSA-376117 JLP interacts with CDO complex IEA Homo sapiens 37565 R-HSA-376119 https://reactome.org/PathwayBrowser/#/R-HSA-376119 Interaction of Bnip-2 with Cdc42 IEA Homo sapiens 37565 R-HSA-377186 https://reactome.org/PathwayBrowser/#/R-HSA-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) TAS Homo sapiens 37565 R-HSA-377640 https://reactome.org/PathwayBrowser/#/R-HSA-377640 Autophosphorylation of SRC TAS Homo sapiens 37565 R-HSA-377641 https://reactome.org/PathwayBrowser/#/R-HSA-377641 Clustering of Integrin alphaIIb beta3 complexes TAS Homo sapiens 37565 R-HSA-377643 https://reactome.org/PathwayBrowser/#/R-HSA-377643 Dephosphorylation of inactive SRC by PTPB1 TAS Homo sapiens 37565 R-HSA-377644 https://reactome.org/PathwayBrowser/#/R-HSA-377644 Release of CSK from SRC TAS Homo sapiens 37565 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 37565 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 37565 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 37565 R-HSA-380316 https://reactome.org/PathwayBrowser/#/R-HSA-380316 Association of NuMA with microtubules TAS Homo sapiens 37565 R-HSA-380979 https://reactome.org/PathwayBrowser/#/R-HSA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP TAS Homo sapiens 37565 R-HSA-381607 https://reactome.org/PathwayBrowser/#/R-HSA-381607 Activated Adenylyl cyclase synthesizes cyclic AMP TAS Homo sapiens 37565 R-HSA-381704 https://reactome.org/PathwayBrowser/#/R-HSA-381704 G(s):GTP activates Adenylyl cyclase TAS Homo sapiens 37565 R-HSA-381706 https://reactome.org/PathwayBrowser/#/R-HSA-381706 GLP1R:GLP1 activates G(s) IEA Homo sapiens 37565 R-HSA-381727 https://reactome.org/PathwayBrowser/#/R-HSA-381727 RAP1A exchanges GDP for GTP TAS Homo sapiens 37565 R-HSA-3858475 https://reactome.org/PathwayBrowser/#/R-HSA-3858475 ppDVL recruits RAC TAS Homo sapiens 37565 R-HSA-3858495 https://reactome.org/PathwayBrowser/#/R-HSA-3858495 DAAM1 recruits GTP-bound RHOA TAS Homo sapiens 37565 R-HSA-389348 https://reactome.org/PathwayBrowser/#/R-HSA-389348 Activation of Rac1 by pVav1 TAS Homo sapiens 37565 R-HSA-389350 https://reactome.org/PathwayBrowser/#/R-HSA-389350 Activation of Cdc42 by pVav1 TAS Homo sapiens 37565 R-HSA-389788 https://reactome.org/PathwayBrowser/#/R-HSA-389788 Activation of PAKs by RAC1 and CDC42 TAS Homo sapiens 37565 R-HSA-389954 https://reactome.org/PathwayBrowser/#/R-HSA-389954 Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC IEA Homo sapiens 37565 R-HSA-389955 https://reactome.org/PathwayBrowser/#/R-HSA-389955 Beta-tubulin:GTP: Cofactor A+ Cofactor D -> Beta-tubulin:GTP:Cofactor D + Cofactor A IEA Homo sapiens 37565 R-HSA-389956 https://reactome.org/PathwayBrowser/#/R-HSA-389956 Beta-tubulin:GTP + Cofactor A -> Beta-tubulin:GTP: Cofactor A IEA Homo sapiens 37565 R-HSA-389963 https://reactome.org/PathwayBrowser/#/R-HSA-389963 alpha-tubulin:GTP:Cofactor B +Cofactor E -> alpha-tubulin:GTP: Cofactor E +Cofactor B IEA Homo sapiens 37565 R-HSA-389964 https://reactome.org/PathwayBrowser/#/R-HSA-389964 Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E+ Cofactor C-> Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E:Cofactor C IEA Homo sapiens 37565 R-HSA-389969 https://reactome.org/PathwayBrowser/#/R-HSA-389969 Beta-tubulin:GTP + Cofactor D -> Beta-tubulin:GTP: Cofactor D IEA Homo sapiens 37565 R-HSA-389972 https://reactome.org/PathwayBrowser/#/R-HSA-389972 alpha-tubulin:GTP + Cofactor B -> alpha-tubulin:GTP: Cofactor B IEA Homo sapiens 37565 R-HSA-389974 https://reactome.org/PathwayBrowser/#/R-HSA-389974 Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E:Cofactor C-> Beta-tubulin:GDP :alpha-tubulin:GTP heterodimer +Cofactor E+ Cofactor D+ Cofactor C+ Pi IEA Homo sapiens 37565 R-HSA-389976 https://reactome.org/PathwayBrowser/#/R-HSA-389976 Beta-tubulin:GTP:Cofactor D+alpha-tubulin:GTP:Cofactor E-> Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E IEA Homo sapiens 37565 R-HSA-389978 https://reactome.org/PathwayBrowser/#/R-HSA-389978 alpha-tubulin:GTP + Cofactor E -> alpha-tubulin:GTP:Cofactor E IEA Homo sapiens 37565 R-HSA-392054 https://reactome.org/PathwayBrowser/#/R-HSA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras TAS Homo sapiens 37565 R-HSA-392064 https://reactome.org/PathwayBrowser/#/R-HSA-392064 G alpha (z) inhibits adenylate cyclase TAS Homo sapiens 37565 R-HSA-392129 https://reactome.org/PathwayBrowser/#/R-HSA-392129 Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate IEA Homo sapiens 37565 R-HSA-392133 https://reactome.org/PathwayBrowser/#/R-HSA-392133 G alpha (z) auto-inactivates by hydrolysing GTP to GDP IEA Homo sapiens 37565 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 37565 R-HSA-392195 https://reactome.org/PathwayBrowser/#/R-HSA-392195 Gi activation by P2Y purinoceptor 12 TAS Homo sapiens 37565 R-HSA-392202 https://reactome.org/PathwayBrowser/#/R-HSA-392202 Dissociation of the P2Y purinoceptor 12:Gi complex TAS Homo sapiens 37565 R-HSA-392206 https://reactome.org/PathwayBrowser/#/R-HSA-392206 G alpha (i) inhibits adenylate cyclase IEA Homo sapiens 37565 R-HSA-392212 https://reactome.org/PathwayBrowser/#/R-HSA-392212 G alpha (i) auto-inactivates by hydrolysing GTP to GDP IEA Homo sapiens 37565 R-HSA-392513 https://reactome.org/PathwayBrowser/#/R-HSA-392513 Rap1 signal termination by Rap1GAPs TAS Homo sapiens 37565 R-HSA-392835 https://reactome.org/PathwayBrowser/#/R-HSA-392835 Rap1 sequesters Raf1 to inhibit ERK cascade TAS Homo sapiens 37565 R-HSA-3928576 https://reactome.org/PathwayBrowser/#/R-HSA-3928576 RHOA:GTP binds ROCK, activating it TAS Homo sapiens 37565 R-HSA-3928577 https://reactome.org/PathwayBrowser/#/R-HSA-3928577 ROCK phosphorylates LIMK1,2 IEA Homo sapiens 37565 R-HSA-3928592 https://reactome.org/PathwayBrowser/#/R-HSA-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it TAS Homo sapiens 37565 R-HSA-3928595 https://reactome.org/PathwayBrowser/#/R-HSA-3928595 N-WASP binds ARP2/3 and G-actin TAS Homo sapiens 37565 R-HSA-3928601 https://reactome.org/PathwayBrowser/#/R-HSA-3928601 CDC42 and PIP2 bind WASL, activating it TAS Homo sapiens 37565 R-HSA-3928612 https://reactome.org/PathwayBrowser/#/R-HSA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 37565 R-HSA-3928616 https://reactome.org/PathwayBrowser/#/R-HSA-3928616 Activated ROCK phosphorylates MRLCs IEA Homo sapiens 37565 R-HSA-3928619 https://reactome.org/PathwayBrowser/#/R-HSA-3928619 PAK1 binds RAC1:GTP TAS Homo sapiens 37565 R-HSA-3928620 https://reactome.org/PathwayBrowser/#/R-HSA-3928620 PAK1 autophosphorylates TAS Homo sapiens 37565 R-HSA-3928625 https://reactome.org/PathwayBrowser/#/R-HSA-3928625 PAKs autophosphorylate TAS Homo sapiens 37565 R-HSA-3928628 https://reactome.org/PathwayBrowser/#/R-HSA-3928628 VAV exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 37565 R-HSA-3928632 https://reactome.org/PathwayBrowser/#/R-HSA-3928632 ITSN1 exchanges GTP for GDP on CDC42, activating it IEA Homo sapiens 37565 R-HSA-3928633 https://reactome.org/PathwayBrowser/#/R-HSA-3928633 bPIX exchanges GTP for GDP on RAC, activating it TAS Homo sapiens 37565 R-HSA-3928640 https://reactome.org/PathwayBrowser/#/R-HSA-3928640 PAKs phosphorylate MLC TAS Homo sapiens 37565 R-HSA-3928641 https://reactome.org/PathwayBrowser/#/R-HSA-3928641 PAK binds RAC and bPIX TAS Homo sapiens 37565 R-HSA-3928642 https://reactome.org/PathwayBrowser/#/R-HSA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 37565 R-HSA-3928647 https://reactome.org/PathwayBrowser/#/R-HSA-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 TAS Homo sapiens 37565 R-HSA-3928651 https://reactome.org/PathwayBrowser/#/R-HSA-3928651 NGEF exchanges GTP for GDP on RHOA TAS Homo sapiens 37565 R-HSA-392870 https://reactome.org/PathwayBrowser/#/R-HSA-392870 Gs activation by prostacyclin receptor TAS Homo sapiens 37565 R-HSA-392874 https://reactome.org/PathwayBrowser/#/R-HSA-392874 Dissociation of the Prostacyclin receptor:Gs complex IEA Homo sapiens 37565 R-HSA-3965444 https://reactome.org/PathwayBrowser/#/R-HSA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange TAS Homo sapiens 37565 R-HSA-3965447 https://reactome.org/PathwayBrowser/#/R-HSA-3965447 G-protein subunits dissociate from WNT:FZD complex TAS Homo sapiens 37565 R-HSA-397835 https://reactome.org/PathwayBrowser/#/R-HSA-397835 Thrombin-activated PARs:Gq (active) dissociate TAS Homo sapiens 37565 R-HSA-397891 https://reactome.org/PathwayBrowser/#/R-HSA-397891 Thrombin-activated PARs:G12/13 (active) dissociate TAS Homo sapiens 37565 R-HSA-398184 https://reactome.org/PathwayBrowser/#/R-HSA-398184 LARG activation by G alpha 12/13 TAS Homo sapiens 37565 R-HSA-398185 https://reactome.org/PathwayBrowser/#/R-HSA-398185 LARG binds plexin B1 TAS Homo sapiens 37565 R-HSA-398188 https://reactome.org/PathwayBrowser/#/R-HSA-398188 PLC beta is activated by G alpha (q) IEA Homo sapiens 37565 R-HSA-399928 https://reactome.org/PathwayBrowser/#/R-HSA-399928 Recruitment of Rnd1 to Plexin A IEA Homo sapiens 37565 R-HSA-399930 https://reactome.org/PathwayBrowser/#/R-HSA-399930 Activation of PAK by Rac1 TAS Homo sapiens 37565 R-HSA-399935 https://reactome.org/PathwayBrowser/#/R-HSA-399935 Inactivation of R-Ras by Sema3A-Plexin-A GAP activity IEA Homo sapiens 37565 R-HSA-399938 https://reactome.org/PathwayBrowser/#/R-HSA-399938 Activation of Rac1 by FARP2 IEA Homo sapiens 37565 R-HSA-399939 https://reactome.org/PathwayBrowser/#/R-HSA-399939 Autophosphorylation of PAK TAS Homo sapiens 37565 R-HSA-399941 https://reactome.org/PathwayBrowser/#/R-HSA-399941 Rac1 binds PlexinA IEA Homo sapiens 37565 R-HSA-399952 https://reactome.org/PathwayBrowser/#/R-HSA-399952 Phosphorylation of LIMK-1 by PAK TAS Homo sapiens 37565 R-HSA-399995 https://reactome.org/PathwayBrowser/#/R-HSA-399995 Muscarinic Acetylcholine Receptor M3 activates Gq IEA Homo sapiens 37565 R-HSA-399998 https://reactome.org/PathwayBrowser/#/R-HSA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate TAS Homo sapiens 37565 R-HSA-400023 https://reactome.org/PathwayBrowser/#/R-HSA-400023 Gq alpha activates Phospholipase C beta IEA Homo sapiens 37565 R-HSA-400027 https://reactome.org/PathwayBrowser/#/R-HSA-400027 Gq alpha:G beta:G gamma dissociates to Gq alpha:GTP and G beta:G gamma TAS Homo sapiens 37565 R-HSA-400037 https://reactome.org/PathwayBrowser/#/R-HSA-400037 Gi,Go Heterotrimeric G-protein complex dissociates TAS Homo sapiens 37565 R-HSA-400063 https://reactome.org/PathwayBrowser/#/R-HSA-400063 Low conductance potassium channels in pancreatic beta cells open in response to epinephrine IEA Homo sapiens 37565 R-HSA-400092 https://reactome.org/PathwayBrowser/#/R-HSA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins TAS Homo sapiens 37565 R-HSA-400586 https://reactome.org/PathwayBrowser/#/R-HSA-400586 G alpha (q) binds to Trio family RhoGEFs TAS Homo sapiens 37565 R-HSA-400677 https://reactome.org/PathwayBrowser/#/R-HSA-400677 Rnd1 interacts with Plexin-B1:Sema4D TAS Homo sapiens 37565 R-HSA-400682 https://reactome.org/PathwayBrowser/#/R-HSA-400682 Active Rac1 interacts with Plexin-B1:Sema4D TAS Homo sapiens 37565 R-HSA-4086392 https://reactome.org/PathwayBrowser/#/R-HSA-4086392 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 37565 R-HSA-4086393 https://reactome.org/PathwayBrowser/#/R-HSA-4086393 G alpha t2 binds and activates PDE6 IEA Homo sapiens 37565 R-HSA-4093331 https://reactome.org/PathwayBrowser/#/R-HSA-4093331 Ras:GTP binds p120-RasGAP TAS Homo sapiens 37565 R-HSA-4093336 https://reactome.org/PathwayBrowser/#/R-HSA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 37565 R-HSA-4093339 https://reactome.org/PathwayBrowser/#/R-HSA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it TAS Homo sapiens 37565 R-HSA-416358 https://reactome.org/PathwayBrowser/#/R-HSA-416358 G alpha (q) inhibits PI3K alpha TAS Homo sapiens 37565 R-HSA-416510 https://reactome.org/PathwayBrowser/#/R-HSA-416510 GRK5 sequesters activated Gq IEA Homo sapiens 37565 R-HSA-416516 https://reactome.org/PathwayBrowser/#/R-HSA-416516 GRK2 sequesters activated Gq TAS Homo sapiens 37565 R-HSA-416530 https://reactome.org/PathwayBrowser/#/R-HSA-416530 FFAR1:FFAR1 ligands activate Gq TAS Homo sapiens 37565 R-HSA-416546 https://reactome.org/PathwayBrowser/#/R-HSA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity TAS Homo sapiens 37565 R-HSA-416559 https://reactome.org/PathwayBrowser/#/R-HSA-416559 Inactivation of Rho-GTP by p190RhoGAP TAS Homo sapiens 37565 R-HSA-416562 https://reactome.org/PathwayBrowser/#/R-HSA-416562 p190RhoGAP binds Plexin-B1 TAS Homo sapiens 37565 R-HSA-416588 https://reactome.org/PathwayBrowser/#/R-HSA-416588 Activation of Rho by LARG and PDZ-RhoGEF TAS Homo sapiens 37565 R-HSA-418574 https://reactome.org/PathwayBrowser/#/R-HSA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP TAS Homo sapiens 37565 R-HSA-418576 https://reactome.org/PathwayBrowser/#/R-HSA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex TAS Homo sapiens 37565 R-HSA-418579 https://reactome.org/PathwayBrowser/#/R-HSA-418579 Gq activation by P2Y purinoceptor 1 IEA Homo sapiens 37565 R-HSA-418582 https://reactome.org/PathwayBrowser/#/R-HSA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP TAS Homo sapiens 37565 R-HSA-418850 https://reactome.org/PathwayBrowser/#/R-HSA-418850 Activation of Cdc42 TAS Homo sapiens 37565 R-HSA-418856 https://reactome.org/PathwayBrowser/#/R-HSA-418856 Activation of Rac1 TAS Homo sapiens 37565 R-HSA-418865 https://reactome.org/PathwayBrowser/#/R-HSA-418865 Recruitment of ABLIM to the plasma membrane IEA Homo sapiens 37565 R-HSA-418874 https://reactome.org/PathwayBrowser/#/R-HSA-418874 Recruitment and activation of N-WASP by Cdc42 TAS Homo sapiens 37565 R-HSA-419049 https://reactome.org/PathwayBrowser/#/R-HSA-419049 ROCK activation by RHO TAS Homo sapiens 37565 R-HSA-419083 https://reactome.org/PathwayBrowser/#/R-HSA-419083 Myosin phosphatase inactivation by ROCK IEA Homo sapiens 37565 R-HSA-419087 https://reactome.org/PathwayBrowser/#/R-HSA-419087 LIM kinase phosphorylation by ROCK IEA Homo sapiens 37565 R-HSA-419166 https://reactome.org/PathwayBrowser/#/R-HSA-419166 GEFs activate RhoA,B,C TAS Homo sapiens 37565 R-HSA-419197 https://reactome.org/PathwayBrowser/#/R-HSA-419197 Myosin regulatory light chain phosphorylation by ROCK IEA Homo sapiens 37565 R-HSA-420883 https://reactome.org/PathwayBrowser/#/R-HSA-420883 Opsins act as GEFs for G alpha-t TAS Homo sapiens 37565 R-HSA-421831 https://reactome.org/PathwayBrowser/#/R-HSA-421831 trans-Golgi Network Coat Assembly TAS Homo sapiens 37565 R-HSA-421833 https://reactome.org/PathwayBrowser/#/R-HSA-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture TAS Homo sapiens 37565 R-HSA-421835 https://reactome.org/PathwayBrowser/#/R-HSA-421835 trans-Golgi Network Vesicle Scission TAS Homo sapiens 37565 R-HSA-422320 https://reactome.org/PathwayBrowser/#/R-HSA-422320 Heterotrimeric G(s) complex dissociates TAS Homo sapiens 37565 R-HSA-428522 https://reactome.org/PathwayBrowser/#/R-HSA-428522 Inactivation of RAC1 IEA Homo sapiens 37565 R-HSA-428533 https://reactome.org/PathwayBrowser/#/R-HSA-428533 Inactivation of CDC42 IEA Homo sapiens 37565 R-HSA-428535 https://reactome.org/PathwayBrowser/#/R-HSA-428535 Activation of RAC1 by SOS IEA Homo sapiens 37565 R-HSA-428750 https://reactome.org/PathwayBrowser/#/R-HSA-428750 Gq activation by TP receptor TAS Homo sapiens 37565 R-HSA-428752 https://reactome.org/PathwayBrowser/#/R-HSA-428752 Dissociation of the TP:Gq complex TAS Homo sapiens 37565 R-HSA-428917 https://reactome.org/PathwayBrowser/#/R-HSA-428917 G13 activation by TP receptor TAS Homo sapiens 37565 R-HSA-428918 https://reactome.org/PathwayBrowser/#/R-HSA-428918 Dissociation of the TP:G13 complex TAS Homo sapiens 37565 R-HSA-428941 https://reactome.org/PathwayBrowser/#/R-HSA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha TAS Homo sapiens 37565 R-HSA-429415 https://reactome.org/PathwayBrowser/#/R-HSA-429415 SYK binds to integrin alphaIIb beta3 TAS Homo sapiens 37565 R-HSA-429441 https://reactome.org/PathwayBrowser/#/R-HSA-429441 SYK activation by SRC TAS Homo sapiens 37565 R-HSA-432096 https://reactome.org/PathwayBrowser/#/R-HSA-432096 Activated integrin alphaIIb beta3 binds SHC1 TAS Homo sapiens 37565 R-HSA-432195 https://reactome.org/PathwayBrowser/#/R-HSA-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP TAS Homo sapiens 37565 R-HSA-432706 https://reactome.org/PathwayBrowser/#/R-HSA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly TAS Homo sapiens 37565 R-HSA-432707 https://reactome.org/PathwayBrowser/#/R-HSA-432707 trans-Golgi Network Lysosomal Vesicle Scission TAS Homo sapiens 37565 R-HSA-432712 https://reactome.org/PathwayBrowser/#/R-HSA-432712 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane TAS Homo sapiens 37565 R-HSA-442273 https://reactome.org/PathwayBrowser/#/R-HSA-442273 VAV1 is a GEF for Rho/Rac family GTPases TAS Homo sapiens 37565 R-HSA-442291 https://reactome.org/PathwayBrowser/#/R-HSA-442291 VAV2 is a GEF for Rho/Rac family kinases TAS Homo sapiens 37565 R-HSA-442314 https://reactome.org/PathwayBrowser/#/R-HSA-442314 VAV3 is a GEF for Rho/Rac family kinases TAS Homo sapiens 37565 R-HSA-442586 https://reactome.org/PathwayBrowser/#/R-HSA-442586 Activation of WASP and N-WASP by CDC42 IEA Homo sapiens 37565 R-HSA-442592 https://reactome.org/PathwayBrowser/#/R-HSA-442592 WASPs or WAVEs activate the ARP2/3 complex IEA Homo sapiens 37565 R-HSA-442732 https://reactome.org/PathwayBrowser/#/R-HSA-442732 NMDA-activated RASGRF1 activates RAS IEA Homo sapiens 37565 R-HSA-443905 https://reactome.org/PathwayBrowser/#/R-HSA-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow TAS Homo sapiens 37565 R-HSA-443910 https://reactome.org/PathwayBrowser/#/R-HSA-443910 SHC1 dissociates from integrin alphaIIb beta3 TAS Homo sapiens 37565 R-HSA-445064 https://reactome.org/PathwayBrowser/#/R-HSA-445064 Activation of Rac1 by VAV2 TAS Homo sapiens 37565 R-HSA-445071 https://reactome.org/PathwayBrowser/#/R-HSA-445071 Reinsertion of L1 into the plasma membrane TAS Homo sapiens 37565 R-HSA-445072 https://reactome.org/PathwayBrowser/#/R-HSA-445072 Interaction of PAK1 with Rac1-GTP TAS Homo sapiens 37565 R-HSA-445077 https://reactome.org/PathwayBrowser/#/R-HSA-445077 Transport of L1 from C-domain to P-domain IEA Homo sapiens 37565 R-HSA-446221 https://reactome.org/PathwayBrowser/#/R-HSA-446221 Mannose-1-phosphate converted to GDP-Mannose IEA Homo sapiens 37565 R-HSA-447074 https://reactome.org/PathwayBrowser/#/R-HSA-447074 AMPK phosphorylates Raptor in the mTORC1 complex TAS Homo sapiens 37565 R-HSA-448951 https://reactome.org/PathwayBrowser/#/R-HSA-448951 Activation of p38 alpha/beta MAPK IEA Homo sapiens 37565 R-HSA-448957 https://reactome.org/PathwayBrowser/#/R-HSA-448957 Interaction of p38 MAPK with JLP IEA Homo sapiens 37565 R-HSA-448958 https://reactome.org/PathwayBrowser/#/R-HSA-448958 Nuclear translocation of p38 MAPK TAS Homo sapiens 37565 R-HSA-449200 https://reactome.org/PathwayBrowser/#/R-HSA-449200 Interaction of ABL1 with CDO complex IEA Homo sapiens 37565 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 37565 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 37565 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 37565 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 37565 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 37565 R-HSA-5218804 https://reactome.org/PathwayBrowser/#/R-HSA-5218804 p38 MAPK activation by VEGFR TAS Homo sapiens 37565 R-HSA-5218812 https://reactome.org/PathwayBrowser/#/R-HSA-5218812 FYN phosphorylates PAK2 TAS Homo sapiens 37565 R-HSA-5218814 https://reactome.org/PathwayBrowser/#/R-HSA-5218814 PAK2 autophorylates TAS Homo sapiens 37565 R-HSA-5218826 https://reactome.org/PathwayBrowser/#/R-HSA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 TAS Homo sapiens 37565 R-HSA-5218827 https://reactome.org/PathwayBrowser/#/R-HSA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 TAS Homo sapiens 37565 R-HSA-5218829 https://reactome.org/PathwayBrowser/#/R-HSA-5218829 VEGF induces CDC42 activation by unknown mechanism TAS Homo sapiens 37565 R-HSA-5218832 https://reactome.org/PathwayBrowser/#/R-HSA-5218832 CDC42:GTP binds PAK2 TAS Homo sapiens 37565 R-HSA-5218839 https://reactome.org/PathwayBrowser/#/R-HSA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 TAS Homo sapiens 37565 R-HSA-5218841 https://reactome.org/PathwayBrowser/#/R-HSA-5218841 NADPH oxidase 2 generates superoxide from oxygen TAS Homo sapiens 37565 R-HSA-5218845 https://reactome.org/PathwayBrowser/#/R-HSA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate TAS Homo sapiens 37565 R-HSA-5218850 https://reactome.org/PathwayBrowser/#/R-HSA-5218850 VAV exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 37565 R-HSA-5228992 https://reactome.org/PathwayBrowser/#/R-HSA-5228992 ROCK1,ROCK2 are activated TAS Homo sapiens 37565 R-HSA-5250209 https://reactome.org/PathwayBrowser/#/R-HSA-5250209 ARL2:GTP:ARL2BP binds SLC25A4 TAS Homo sapiens 37565 R-HSA-5250210 https://reactome.org/PathwayBrowser/#/R-HSA-5250210 ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix TAS Homo sapiens 37565 R-HSA-5250217 https://reactome.org/PathwayBrowser/#/R-HSA-5250217 ARL2:GTP binds ARL2BP TAS Homo sapiens 37565 R-HSA-5333615 https://reactome.org/PathwayBrowser/#/R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC IEA Homo sapiens 37565 R-HSA-5357445 https://reactome.org/PathwayBrowser/#/R-HSA-5357445 PAK1-3 dimer disassociates TAS Homo sapiens 37565 R-HSA-5357472 https://reactome.org/PathwayBrowser/#/R-HSA-5357472 PAK1-3 autophosphorylates TAS Homo sapiens 37565 R-HSA-5357483 https://reactome.org/PathwayBrowser/#/R-HSA-5357483 RAC1 binds PAK1-3 TAS Homo sapiens 37565 R-HSA-5389839 https://reactome.org/PathwayBrowser/#/R-HSA-5389839 39S subunit binds 28S subunit:mRNA:fMet-tRNA IEA Homo sapiens 37565 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 37565 R-HSA-5389845 https://reactome.org/PathwayBrowser/#/R-HSA-5389845 TUFM:GTP binds aminoacyl-tRNA IEA Homo sapiens 37565 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 37565 R-HSA-5389849 https://reactome.org/PathwayBrowser/#/R-HSA-5389849 28S subunit:MTIF3 binds MTIF2:GTP, mRNA, and formylMet-tRNA IEA Homo sapiens 37565 R-HSA-5419261 https://reactome.org/PathwayBrowser/#/R-HSA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP TAS Homo sapiens 37565 R-HSA-5419264 https://reactome.org/PathwayBrowser/#/R-HSA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA TAS Homo sapiens 37565 R-HSA-5419268 https://reactome.org/PathwayBrowser/#/R-HSA-5419268 TUFM binds GTP displacing TSFM IEA Homo sapiens 37565 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 37565 R-HSA-5419273 https://reactome.org/PathwayBrowser/#/R-HSA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits TAS Homo sapiens 37565 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 37565 R-HSA-5419279 https://reactome.org/PathwayBrowser/#/R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) IEA Homo sapiens 37565 R-HSA-555065 https://reactome.org/PathwayBrowser/#/R-HSA-555065 Formation of clathrin coated vesicle TAS Homo sapiens 37565 R-HSA-5578744 https://reactome.org/PathwayBrowser/#/R-HSA-5578744 Importin-8 imports AGO2:miRNA into the nucleus TAS Homo sapiens 37565 R-HSA-5610727 https://reactome.org/PathwayBrowser/#/R-HSA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner TAS Homo sapiens 37565 R-HSA-5610733 https://reactome.org/PathwayBrowser/#/R-HSA-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules TAS Homo sapiens 37565 R-HSA-5610767 https://reactome.org/PathwayBrowser/#/R-HSA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip TAS Homo sapiens 37565 R-HSA-5617816 https://reactome.org/PathwayBrowser/#/R-HSA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A TAS Homo sapiens 37565 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 37565 R-HSA-5618328 https://reactome.org/PathwayBrowser/#/R-HSA-5618328 ATAT acetylates microtubules TAS Homo sapiens 37565 R-HSA-5618331 https://reactome.org/PathwayBrowser/#/R-HSA-5618331 HDAC6 deacetylates microtubules TAS Homo sapiens 37565 R-HSA-5620914 https://reactome.org/PathwayBrowser/#/R-HSA-5620914 ARF4:GTP binds VxPx-motifs of membrane proteins TAS Homo sapiens 37565 R-HSA-5620918 https://reactome.org/PathwayBrowser/#/R-HSA-5620918 ASAP1 dimer binds membrane proteins IEA Homo sapiens 37565 R-HSA-5620921 https://reactome.org/PathwayBrowser/#/R-HSA-5620921 ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex TAS Homo sapiens 37565 R-HSA-5621573 https://reactome.org/PathwayBrowser/#/R-HSA-5621573 CD209 activate GTPase RAS TAS Homo sapiens 37565 R-HSA-5623508 https://reactome.org/PathwayBrowser/#/R-HSA-5623508 GBF1 stimulates nucleotide exchange on ARF4 TAS Homo sapiens 37565 R-HSA-5623513 https://reactome.org/PathwayBrowser/#/R-HSA-5623513 ASAP1 stimulates GTPase activity of ARF4 TAS Homo sapiens 37565 R-HSA-5623519 https://reactome.org/PathwayBrowser/#/R-HSA-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex TAS Homo sapiens 37565 R-HSA-5623521 https://reactome.org/PathwayBrowser/#/R-HSA-5623521 RAB3IP stimulates nucleotide exchange on RAB8A TAS Homo sapiens 37565 R-HSA-5623524 https://reactome.org/PathwayBrowser/#/R-HSA-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex TAS Homo sapiens 37565 R-HSA-5623525 https://reactome.org/PathwayBrowser/#/R-HSA-5623525 Cargo-carrying vesicles bud from the TGN TAS Homo sapiens 37565 R-HSA-5623527 https://reactome.org/PathwayBrowser/#/R-HSA-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane TAS Homo sapiens 37565 R-HSA-5623622 https://reactome.org/PathwayBrowser/#/R-HSA-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 TAS Homo sapiens 37565 R-HSA-5623632 https://reactome.org/PathwayBrowser/#/R-HSA-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 TAS Homo sapiens 37565 R-HSA-5623667 https://reactome.org/PathwayBrowser/#/R-HSA-5623667 PDPK1 phosphorylates PKN1,2,3 TAS Homo sapiens 37565 R-HSA-5624126 https://reactome.org/PathwayBrowser/#/R-HSA-5624126 ARL6:GTP and the BBSome bind ciliary cargo TAS Homo sapiens 37565 R-HSA-5624127 https://reactome.org/PathwayBrowser/#/R-HSA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium TAS Homo sapiens 37565 R-HSA-5624486 https://reactome.org/PathwayBrowser/#/R-HSA-5624486 SFKs phosphorylates RAF1 on Y340,Y341 TAS Homo sapiens 37565 R-HSA-5624492 https://reactome.org/PathwayBrowser/#/R-HSA-5624492 PAK phosphorylates p21 RAF1 on S338 TAS Homo sapiens 37565 R-HSA-5624494 https://reactome.org/PathwayBrowser/#/R-HSA-5624494 RAF1 binds p21 RAS:GTP TAS Homo sapiens 37565 R-HSA-5625901 https://reactome.org/PathwayBrowser/#/R-HSA-5625901 CIT (citron kinase) binds activated RHOA, RHOB, RHOC and RAC1 IEA Homo sapiens 37565 R-HSA-5625959 https://reactome.org/PathwayBrowser/#/R-HSA-5625959 Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) TAS Homo sapiens 37565 R-HSA-5626469 https://reactome.org/PathwayBrowser/#/R-HSA-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs TAS Homo sapiens 37565 R-HSA-5626507 https://reactome.org/PathwayBrowser/#/R-HSA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin TAS Homo sapiens 37565 R-HSA-5626549 https://reactome.org/PathwayBrowser/#/R-HSA-5626549 IQGAPs bind CALM1 TAS Homo sapiens 37565 R-HSA-5627071 https://reactome.org/PathwayBrowser/#/R-HSA-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane TAS Homo sapiens 37565 R-HSA-5627072 https://reactome.org/PathwayBrowser/#/R-HSA-5627072 RHOQ binds GOPC:CFTR TAS Homo sapiens 37565 R-HSA-5627775 https://reactome.org/PathwayBrowser/#/R-HSA-5627775 Autophosphorylation of PAK1,2,3 TAS Homo sapiens 37565 R-HSA-5637806 https://reactome.org/PathwayBrowser/#/R-HSA-5637806 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with p-EGFRvIII) TAS Homo sapiens 37565 R-HSA-5637808 https://reactome.org/PathwayBrowser/#/R-HSA-5637808 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and p-EGFRvIII) TAS Homo sapiens 37565 R-HSA-5638009 https://reactome.org/PathwayBrowser/#/R-HSA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body TAS Homo sapiens 37565 R-HSA-5638014 https://reactome.org/PathwayBrowser/#/R-HSA-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP TAS Homo sapiens 37565 R-HSA-5653957 https://reactome.org/PathwayBrowser/#/R-HSA-5653957 Rag dimer formation TAS Homo sapiens 37565 R-HSA-5653968 https://reactome.org/PathwayBrowser/#/R-HSA-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 TAS Homo sapiens 37565 R-HSA-5653974 https://reactome.org/PathwayBrowser/#/R-HSA-5653974 Ragulator binds Rag dimers TAS Homo sapiens 37565 R-HSA-5654392 https://reactome.org/PathwayBrowser/#/R-HSA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5654402 https://reactome.org/PathwayBrowser/#/R-HSA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5654413 https://reactome.org/PathwayBrowser/#/R-HSA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5654426 https://reactome.org/PathwayBrowser/#/R-HSA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5654600 https://reactome.org/PathwayBrowser/#/R-HSA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5654618 https://reactome.org/PathwayBrowser/#/R-HSA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5654647 https://reactome.org/PathwayBrowser/#/R-HSA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5654663 https://reactome.org/PathwayBrowser/#/R-HSA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5655241 https://reactome.org/PathwayBrowser/#/R-HSA-5655241 Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5655277 https://reactome.org/PathwayBrowser/#/R-HSA-5655277 Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5655326 https://reactome.org/PathwayBrowser/#/R-HSA-5655326 Activated FGFR1 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5655347 https://reactome.org/PathwayBrowser/#/R-HSA-5655347 Activated FGFR4 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5658231 https://reactome.org/PathwayBrowser/#/R-HSA-5658231 RAS GAPs stimulate RAS GTPase activity TAS Homo sapiens 37565 R-HSA-5658435 https://reactome.org/PathwayBrowser/#/R-HSA-5658435 RAS GAPs bind RAS:GTP TAS Homo sapiens 37565 R-HSA-5663232 https://reactome.org/PathwayBrowser/#/R-HSA-5663232 FMNL1 binds RAC1:GTP IEA Homo sapiens 37565 R-HSA-5665659 https://reactome.org/PathwayBrowser/#/R-HSA-5665659 RAC1:GTP:FMNL1 binds profilin:G-actin IEA Homo sapiens 37565 R-HSA-5665686 https://reactome.org/PathwayBrowser/#/R-HSA-5665686 FMNL1 binds CDC42:GTP IEA Homo sapiens 37565 R-HSA-5665727 https://reactome.org/PathwayBrowser/#/R-HSA-5665727 FMNL2 binds CDC42:GTP TAS Homo sapiens 37565 R-HSA-5665748 https://reactome.org/PathwayBrowser/#/R-HSA-5665748 FMNL2 binds RHOC:GTP TAS Homo sapiens 37565 R-HSA-5665751 https://reactome.org/PathwayBrowser/#/R-HSA-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin TAS Homo sapiens 37565 R-HSA-5665761 https://reactome.org/PathwayBrowser/#/R-HSA-5665761 FMNL3 binds RHOC:GTP TAS Homo sapiens 37565 R-HSA-5665767 https://reactome.org/PathwayBrowser/#/R-HSA-5665767 Activated FMNL3 binds G-actin TAS Homo sapiens 37565 R-HSA-5665802 https://reactome.org/PathwayBrowser/#/R-HSA-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin TAS Homo sapiens 37565 R-HSA-5665809 https://reactome.org/PathwayBrowser/#/R-HSA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments TAS Homo sapiens 37565 R-HSA-5665982 https://reactome.org/PathwayBrowser/#/R-HSA-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 TAS Homo sapiens 37565 R-HSA-5665989 https://reactome.org/PathwayBrowser/#/R-HSA-5665989 DIAPH1 binds RHOA:GTP TAS Homo sapiens 37565 R-HSA-5666070 https://reactome.org/PathwayBrowser/#/R-HSA-5666070 RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes TAS Homo sapiens 37565 R-HSA-5666088 https://reactome.org/PathwayBrowser/#/R-HSA-5666088 RHOD:GTP recruits DAIPH2-3 to endosomes TAS Homo sapiens 37565 R-HSA-5666104 https://reactome.org/PathwayBrowser/#/R-HSA-5666104 RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes TAS Homo sapiens 37565 R-HSA-5666129 https://reactome.org/PathwayBrowser/#/R-HSA-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores TAS Homo sapiens 37565 R-HSA-5666160 https://reactome.org/PathwayBrowser/#/R-HSA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores TAS Homo sapiens 37565 R-HSA-5666169 https://reactome.org/PathwayBrowser/#/R-HSA-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 TAS Homo sapiens 37565 R-HSA-5666178 https://reactome.org/PathwayBrowser/#/R-HSA-5666178 RTKN binds RHOA, RHOC or RHOB IEA Homo sapiens 37565 R-HSA-5666197 https://reactome.org/PathwayBrowser/#/R-HSA-5666197 RHOA:GTP:RTKN binds LIN7B TAS Homo sapiens 37565 R-HSA-5666216 https://reactome.org/PathwayBrowser/#/R-HSA-5666216 RHOA:GTP:RTKN binds TAX1BP3 TAS Homo sapiens 37565 R-HSA-5667008 https://reactome.org/PathwayBrowser/#/R-HSA-5667008 RHOA:GTP binds RHPN1 or RHPN2 TAS Homo sapiens 37565 R-HSA-5667037 https://reactome.org/PathwayBrowser/#/R-HSA-5667037 RHPN2 binds RHOB:GTP IEA Homo sapiens 37565 R-HSA-5667052 https://reactome.org/PathwayBrowser/#/R-HSA-5667052 ROPN1 binds RHOA:GTP:RHPN1 IEA Homo sapiens 37565 R-HSA-5668605 https://reactome.org/PathwayBrowser/#/R-HSA-5668605 RAC2:GTP binds NOX2 complex TAS Homo sapiens 37565 R-HSA-5668629 https://reactome.org/PathwayBrowser/#/R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP TAS Homo sapiens 37565 R-HSA-5668714 https://reactome.org/PathwayBrowser/#/R-HSA-5668714 RAC1:GTP binds NOX1 complex TAS Homo sapiens 37565 R-HSA-5668718 https://reactome.org/PathwayBrowser/#/R-HSA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 37565 R-HSA-5668731 https://reactome.org/PathwayBrowser/#/R-HSA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 37565 R-HSA-5668735 https://reactome.org/PathwayBrowser/#/R-HSA-5668735 RAC1:GTP binds NOX3 complex TAS Homo sapiens 37565 R-HSA-5671919 https://reactome.org/PathwayBrowser/#/R-HSA-5671919 Activated CIT phosphorylates MRLCs IEA Homo sapiens 37565 R-HSA-5671970 https://reactome.org/PathwayBrowser/#/R-HSA-5671970 Activated CIT binds KIF14 and PRC1 TAS Homo sapiens 37565 R-HSA-5671993 https://reactome.org/PathwayBrowser/#/R-HSA-5671993 CIT-3 binds DLG4 TAS Homo sapiens 37565 R-HSA-5672010 https://reactome.org/PathwayBrowser/#/R-HSA-5672010 Active MTORC1 phosphorylates ULK1 TAS Homo sapiens 37565 R-HSA-5672017 https://reactome.org/PathwayBrowser/#/R-HSA-5672017 Rheb in the MTORC1 complex hydrolyses GTP TAS Homo sapiens 37565 R-HSA-5672027 https://reactome.org/PathwayBrowser/#/R-HSA-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane TAS Homo sapiens 37565 R-HSA-5672083 https://reactome.org/PathwayBrowser/#/R-HSA-5672083 KTN1 binds Kinesin-1 TAS Homo sapiens 37565 R-HSA-5672304 https://reactome.org/PathwayBrowser/#/R-HSA-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 TAS Homo sapiens 37565 R-HSA-5672329 https://reactome.org/PathwayBrowser/#/R-HSA-5672329 IQGAP1 binds CLIP1 and microtubules TAS Homo sapiens 37565 R-HSA-5672817 https://reactome.org/PathwayBrowser/#/R-HSA-5672817 Active MTORC1 binds the ULK1 complex TAS Homo sapiens 37565 R-HSA-5672824 https://reactome.org/PathwayBrowser/#/R-HSA-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB TAS Homo sapiens 37565 R-HSA-5672828 https://reactome.org/PathwayBrowser/#/R-HSA-5672828 mTORC1 phosphorylates AKT1S1 TAS Homo sapiens 37565 R-HSA-5672843 https://reactome.org/PathwayBrowser/#/R-HSA-5672843 AKT1S1 (PRAS40) binds mTORC1 TAS Homo sapiens 37565 R-HSA-5672950 https://reactome.org/PathwayBrowser/#/R-HSA-5672950 "Activator" RAF:YWHAB dimer binds RAS:GTP TAS Homo sapiens 37565 R-HSA-5672965 https://reactome.org/PathwayBrowser/#/R-HSA-5672965 RAS GEFs promote RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-5672966 https://reactome.org/PathwayBrowser/#/R-HSA-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers TAS Homo sapiens 37565 R-HSA-5672969 https://reactome.org/PathwayBrowser/#/R-HSA-5672969 Phosphorylation of RAF TAS Homo sapiens 37565 R-HSA-5672972 https://reactome.org/PathwayBrowser/#/R-HSA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex TAS Homo sapiens 37565 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 37565 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 37565 R-HSA-5672980 https://reactome.org/PathwayBrowser/#/R-HSA-5672980 Dissociation of RAS:RAF complex TAS Homo sapiens 37565 R-HSA-5673768 https://reactome.org/PathwayBrowser/#/R-HSA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex TAS Homo sapiens 37565 R-HSA-5674018 https://reactome.org/PathwayBrowser/#/R-HSA-5674018 BRAP binds RAS:GTP TAS Homo sapiens 37565 R-HSA-5674022 https://reactome.org/PathwayBrowser/#/R-HSA-5674022 BRAP autoubiquitinates TAS Homo sapiens 37565 R-HSA-5675417 https://reactome.org/PathwayBrowser/#/R-HSA-5675417 PEBP1 binds activated RAF1 TAS Homo sapiens 37565 R-HSA-5675431 https://reactome.org/PathwayBrowser/#/R-HSA-5675431 PP2A dephosphorylates RAF1 TAS Homo sapiens 37565 R-HSA-5675433 https://reactome.org/PathwayBrowser/#/R-HSA-5675433 PP5 dephosphorylates RAF1 S338 TAS Homo sapiens 37565 R-HSA-5675790 https://reactome.org/PathwayBrowser/#/R-HSA-5675790 MTORC1 dissociates from ULK complex TAS Homo sapiens 37565 R-HSA-5686071 https://reactome.org/PathwayBrowser/#/R-HSA-5686071 GRB2-1:SOS1:p-Y-SHC mediated nucleotide exchange of RAS IEA Homo sapiens 37565 R-HSA-5686318 https://reactome.org/PathwayBrowser/#/R-HSA-5686318 GRB2-1:SOS1:p-3Y-SHC1 mediated nucleotide exchange of RAS IEA Homo sapiens 37565 R-HSA-5694409 https://reactome.org/PathwayBrowser/#/R-HSA-5694409 Nucleotide exchange on RAB1 TAS Homo sapiens 37565 R-HSA-5694417 https://reactome.org/PathwayBrowser/#/R-HSA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 TAS Homo sapiens 37565 R-HSA-5694418 https://reactome.org/PathwayBrowser/#/R-HSA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 TAS Homo sapiens 37565 R-HSA-5694441 https://reactome.org/PathwayBrowser/#/R-HSA-5694441 CSNK1D phosphorylates SEC23 TAS Homo sapiens 37565 R-HSA-5694522 https://reactome.org/PathwayBrowser/#/R-HSA-5694522 Inner coat assembly and cargo binding TAS Homo sapiens 37565 R-HSA-5694527 https://reactome.org/PathwayBrowser/#/R-HSA-5694527 Loss of SAR1B GTPase TAS Homo sapiens 37565 R-HSA-5696197 https://reactome.org/PathwayBrowser/#/R-HSA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP TAS Homo sapiens 37565 R-HSA-6782434 https://reactome.org/PathwayBrowser/#/R-HSA-6782434 THG1L transfers GMP to 5' end of tRNA(His) TAS Homo sapiens 37565 R-HSA-6783483 https://reactome.org/PathwayBrowser/#/R-HSA-6783483 tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol TAS Homo sapiens 37565 R-HSA-6785478 https://reactome.org/PathwayBrowser/#/R-HSA-6785478 Processed tRNA binds XPOT and RAN:GTP TAS Homo sapiens 37565 R-HSA-6785648 https://reactome.org/PathwayBrowser/#/R-HSA-6785648 MEMO1 binds RHOA:GTP:DIAPH1 TAS Homo sapiens 37565 R-HSA-6787533 https://reactome.org/PathwayBrowser/#/R-HSA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc TAS Homo sapiens 37565 R-HSA-6788611 https://reactome.org/PathwayBrowser/#/R-HSA-6788611 HYKK phosphorylates 5HLYS TAS Homo sapiens 37565 R-HSA-6789092 https://reactome.org/PathwayBrowser/#/R-HSA-6789092 NOX2 generates superoxide anion from oxygen TAS Homo sapiens 37565 R-HSA-6800138 https://reactome.org/PathwayBrowser/#/R-HSA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer TAS Homo sapiens 37565 R-HSA-6802834 https://reactome.org/PathwayBrowser/#/R-HSA-6802834 RAS GTPase mutants don't hydrolyze GTP TAS Homo sapiens 37565 R-HSA-6802837 https://reactome.org/PathwayBrowser/#/R-HSA-6802837 Loss-of-function NF1 variants don't stimulate RAS GTPase activity TAS Homo sapiens 37565 R-HSA-6802908 https://reactome.org/PathwayBrowser/#/R-HSA-6802908 RAS mutants bind inactive RAF TAS Homo sapiens 37565 R-HSA-6802910 https://reactome.org/PathwayBrowser/#/R-HSA-6802910 Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants TAS Homo sapiens 37565 R-HSA-6802911 https://reactome.org/PathwayBrowser/#/R-HSA-6802911 High kinase activity BRAF complexes phosphorylate MAP2Ks TAS Homo sapiens 37565 R-HSA-6802912 https://reactome.org/PathwayBrowser/#/R-HSA-6802912 High kinase activity BRAF mutants bind MAP2Ks and MAPKs TAS Homo sapiens 37565 R-HSA-6802914 https://reactome.org/PathwayBrowser/#/R-HSA-6802914 RAS:GTP:moderate kinase activity p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 37565 R-HSA-6802915 https://reactome.org/PathwayBrowser/#/R-HSA-6802915 Moderate kinase activity BRAF mutants bind RAS:GTP TAS Homo sapiens 37565 R-HSA-6802916 https://reactome.org/PathwayBrowser/#/R-HSA-6802916 RAF is phosphorylated downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 37565 R-HSA-6802918 https://reactome.org/PathwayBrowser/#/R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants TAS Homo sapiens 37565 R-HSA-6802919 https://reactome.org/PathwayBrowser/#/R-HSA-6802919 RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 37565 R-HSA-6802921 https://reactome.org/PathwayBrowser/#/R-HSA-6802921 Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 37565 R-HSA-6802922 https://reactome.org/PathwayBrowser/#/R-HSA-6802922 Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS TAS Homo sapiens 37565 R-HSA-6802924 https://reactome.org/PathwayBrowser/#/R-HSA-6802924 RAF is phosphorylated downstream of oncogenic RAS TAS Homo sapiens 37565 R-HSA-6802925 https://reactome.org/PathwayBrowser/#/R-HSA-6802925 Mutant RAS:p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 37565 R-HSA-6802926 https://reactome.org/PathwayBrowser/#/R-HSA-6802926 Mutant RAS:p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 37565 R-HSA-6802932 https://reactome.org/PathwayBrowser/#/R-HSA-6802932 Dissociation of BRAF/RAF fusion complex TAS Homo sapiens 37565 R-HSA-6802933 https://reactome.org/PathwayBrowser/#/R-HSA-6802933 p-BRAF and RAF fusion dimers phosphorylate MAP2Ks TAS Homo sapiens 37565 R-HSA-6802934 https://reactome.org/PathwayBrowser/#/R-HSA-6802934 p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs TAS Homo sapiens 37565 R-HSA-6802935 https://reactome.org/PathwayBrowser/#/R-HSA-6802935 MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers TAS Homo sapiens 37565 R-HSA-6802937 https://reactome.org/PathwayBrowser/#/R-HSA-6802937 Inactive BRAF mutants bind mutant RAS:GTP TAS Homo sapiens 37565 R-HSA-6802941 https://reactome.org/PathwayBrowser/#/R-HSA-6802941 RAF is paradoxically phosphorylated downstream of kinase-inactive RAF TAS Homo sapiens 37565 R-HSA-6802942 https://reactome.org/PathwayBrowser/#/R-HSA-6802942 RAS:GTP:p-RAF complexes paradoxically bind MAP2Ks and MAPKs TAS Homo sapiens 37565 R-HSA-6802943 https://reactome.org/PathwayBrowser/#/R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 37565 R-HSA-6803227 https://reactome.org/PathwayBrowser/#/R-HSA-6803227 Dissociation of high activity BRAF complexes TAS Homo sapiens 37565 R-HSA-6803230 https://reactome.org/PathwayBrowser/#/R-HSA-6803230 Dissociation of moderate activity BRAF complexes TAS Homo sapiens 37565 R-HSA-6803233 https://reactome.org/PathwayBrowser/#/R-HSA-6803233 Dissociation of oncogenic RAS:RAF complex TAS Homo sapiens 37565 R-HSA-6803234 https://reactome.org/PathwayBrowser/#/R-HSA-6803234 Dissociation of paradoxically activated RAS:BRAF complexes TAS Homo sapiens 37565 R-HSA-6803240 https://reactome.org/PathwayBrowser/#/R-HSA-6803240 Homo- or heterodimerization of RAF downstream of mutant RAS TAS Homo sapiens 37565 R-HSA-6807864 https://reactome.org/PathwayBrowser/#/R-HSA-6807864 RAB1:GTP recruits GBF1 to the ERGIC TAS Homo sapiens 37565 R-HSA-6807866 https://reactome.org/PathwayBrowser/#/R-HSA-6807866 GBF1 recruits ARF:GDP to the ERGIC TAS Homo sapiens 37565 R-HSA-6807868 https://reactome.org/PathwayBrowser/#/R-HSA-6807868 GBF1 stimulates ARF nucleotide exchange TAS Homo sapiens 37565 R-HSA-6807872 https://reactome.org/PathwayBrowser/#/R-HSA-6807872 Active ARF recruits coatomer TAS Homo sapiens 37565 R-HSA-6807875 https://reactome.org/PathwayBrowser/#/R-HSA-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex TAS Homo sapiens 37565 R-HSA-6807877 https://reactome.org/PathwayBrowser/#/R-HSA-6807877 ARFGAPs stimulate ARF GTPase activity TAS Homo sapiens 37565 R-HSA-6809003 https://reactome.org/PathwayBrowser/#/R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin TAS Homo sapiens 37565 R-HSA-6809006 https://reactome.org/PathwayBrowser/#/R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex TAS Homo sapiens 37565 R-HSA-6809010 https://reactome.org/PathwayBrowser/#/R-HSA-6809010 COPI vesicle uncoating TAS Homo sapiens 37565 R-HSA-6809011 https://reactome.org/PathwayBrowser/#/R-HSA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle TAS Homo sapiens 37565 R-HSA-6811411 https://reactome.org/PathwayBrowser/#/R-HSA-6811411 GBF1 recruits ARF:GDP to the Golgi TAS Homo sapiens 37565 R-HSA-6811412 https://reactome.org/PathwayBrowser/#/R-HSA-6811412 Active ARF recruits coatomer to the Golgi TAS Homo sapiens 37565 R-HSA-6811414 https://reactome.org/PathwayBrowser/#/R-HSA-6811414 GBF1 stimulates nucleotide exchange on ARF TAS Homo sapiens 37565 R-HSA-6811415 https://reactome.org/PathwayBrowser/#/R-HSA-6811415 RAB:GTP recruits GBF1 to the Golgi membrane TAS Homo sapiens 37565 R-HSA-6811417 https://reactome.org/PathwayBrowser/#/R-HSA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi TAS Homo sapiens 37565 R-HSA-6811418 https://reactome.org/PathwayBrowser/#/R-HSA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane TAS Homo sapiens 37565 R-HSA-6811423 https://reactome.org/PathwayBrowser/#/R-HSA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs TAS Homo sapiens 37565 R-HSA-6811426 https://reactome.org/PathwayBrowser/#/R-HSA-6811426 Retrograde COPI vesicles bind kinesin and microtubules TAS Homo sapiens 37565 R-HSA-6811427 https://reactome.org/PathwayBrowser/#/R-HSA-6811427 COPI vesicle uncoating at the ER TAS Homo sapiens 37565 R-HSA-6811429 https://reactome.org/PathwayBrowser/#/R-HSA-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange TAS Homo sapiens 37565 R-HSA-6811431 https://reactome.org/PathwayBrowser/#/R-HSA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles TAS Homo sapiens 37565 R-HSA-6814086 https://reactome.org/PathwayBrowser/#/R-HSA-6814086 ARFRP1 recruits ARL1 to the TGN TAS Homo sapiens 37565 R-HSA-6814088 https://reactome.org/PathwayBrowser/#/R-HSA-6814088 SYS1 binds AcM-ARFRP1 TAS Homo sapiens 37565 R-HSA-6814090 https://reactome.org/PathwayBrowser/#/R-HSA-6814090 NatC acetylates ARFFRP1 IEA Homo sapiens 37565 R-HSA-6814091 https://reactome.org/PathwayBrowser/#/R-HSA-6814091 ARL1 recruits TGN Golgin homodimers TAS Homo sapiens 37565 R-HSA-6814094 https://reactome.org/PathwayBrowser/#/R-HSA-6814094 ARL1:GTP binds ARFIP2 TAS Homo sapiens 37565 R-HSA-6814096 https://reactome.org/PathwayBrowser/#/R-HSA-6814096 ARL1:GTP binds SCOC TAS Homo sapiens 37565 R-HSA-6814549 https://reactome.org/PathwayBrowser/#/R-HSA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding TAS Homo sapiens 37565 R-HSA-6814559 https://reactome.org/PathwayBrowser/#/R-HSA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine TAS Homo sapiens 37565 R-HSA-6814670 https://reactome.org/PathwayBrowser/#/R-HSA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation TAS Homo sapiens 37565 R-HSA-6814671 https://reactome.org/PathwayBrowser/#/R-HSA-6814671 Fusion of late-endosome derived vesicles at the TGN TAS Homo sapiens 37565 R-HSA-6814674 https://reactome.org/PathwayBrowser/#/R-HSA-6814674 Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins TAS Homo sapiens 37565 R-HSA-6814675 https://reactome.org/PathwayBrowser/#/R-HSA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN TAS Homo sapiens 37565 R-HSA-6814682 https://reactome.org/PathwayBrowser/#/R-HSA-6814682 Fusion of early-endosome derived vesicles at the TGN TAS Homo sapiens 37565 R-HSA-6814831 https://reactome.org/PathwayBrowser/#/R-HSA-6814831 TBC1D20 binds RAB1:GTP TAS Homo sapiens 37565 R-HSA-6814833 https://reactome.org/PathwayBrowser/#/R-HSA-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP TAS Homo sapiens 37565 R-HSA-70241 https://reactome.org/PathwayBrowser/#/R-HSA-70241 PCK1 phosphorylates OA to yield PEP TAS Homo sapiens 37565 R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] TAS Homo sapiens 37565 R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] TAS Homo sapiens 37565 R-HSA-71775 https://reactome.org/PathwayBrowser/#/R-HSA-71775 SUCLG1/G2 cleaves succinyl-CoA TAS Homo sapiens 37565 R-HSA-72619 https://reactome.org/PathwayBrowser/#/R-HSA-72619 eIF2:GTP is hydrolyzed, eIFs are released TAS Homo sapiens 37565 R-HSA-72621 https://reactome.org/PathwayBrowser/#/R-HSA-72621 Ribosomal scanning TAS Homo sapiens 37565 R-HSA-72663 https://reactome.org/PathwayBrowser/#/R-HSA-72663 De novo formation of eIF2:GTP TAS Homo sapiens 37565 R-HSA-72669 https://reactome.org/PathwayBrowser/#/R-HSA-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex TAS Homo sapiens 37565 R-HSA-72671 https://reactome.org/PathwayBrowser/#/R-HSA-72671 eIF5B:GTP is hydrolyzed and released TAS Homo sapiens 37565 R-HSA-72672 https://reactome.org/PathwayBrowser/#/R-HSA-72672 The 60S subunit joins the translation initiation complex TAS Homo sapiens 37565 R-HSA-72691 https://reactome.org/PathwayBrowser/#/R-HSA-72691 Formation of the 43S pre-initiation complex TAS Homo sapiens 37565 R-HSA-72697 https://reactome.org/PathwayBrowser/#/R-HSA-72697 Start codon recognition TAS Homo sapiens 37565 R-HSA-72722 https://reactome.org/PathwayBrowser/#/R-HSA-72722 eIF2 activation TAS Homo sapiens 37565 R-HSA-74059 https://reactome.org/PathwayBrowser/#/R-HSA-74059 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 37565 R-HSA-74065 https://reactome.org/PathwayBrowser/#/R-HSA-74065 GNAT1-GTP binds PDE6 and activates it IEA Homo sapiens 37565 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 37565 R-HSA-74885 https://reactome.org/PathwayBrowser/#/R-HSA-74885 GUCYs converts GTP to cGMP TAS Homo sapiens 37565 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 37565 R-HSA-749453 https://reactome.org/PathwayBrowser/#/R-HSA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz TAS Homo sapiens 37565 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 37565 R-HSA-751019 https://reactome.org/PathwayBrowser/#/R-HSA-751019 The Ligand:GPCR:G12/13 complex dissociates TAS Homo sapiens 37565 R-HSA-751024 https://reactome.org/PathwayBrowser/#/R-HSA-751024 The Ligand:GPCR:Gz complex dissociates TAS Homo sapiens 37565 R-HSA-751029 https://reactome.org/PathwayBrowser/#/R-HSA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 TAS Homo sapiens 37565 R-HSA-751040 https://reactome.org/PathwayBrowser/#/R-HSA-751040 PKC phosphorylates G alpha (z) IEA Homo sapiens 37565 R-HSA-77081 https://reactome.org/PathwayBrowser/#/R-HSA-77081 Formation of the CE:GMP intermediate complex TAS Homo sapiens 37565 R-HSA-825631 https://reactome.org/PathwayBrowser/#/R-HSA-825631 Glucagon:GCGR mediates GTP-GDP exchange TAS Homo sapiens 37565 R-HSA-8847534 https://reactome.org/PathwayBrowser/#/R-HSA-8847534 RAB43 hydrolyses GTP TAS Homo sapiens 37565 R-HSA-8847537 https://reactome.org/PathwayBrowser/#/R-HSA-8847537 RAB43:GTP binds USP8NL TAS Homo sapiens 37565 R-HSA-8847544 https://reactome.org/PathwayBrowser/#/R-HSA-8847544 The COG complex and CUX1 and GOLGA5 dimers contribute to intra-Golgi vesicle tethering TAS Homo sapiens 37565 R-HSA-8847887 https://reactome.org/PathwayBrowser/#/R-HSA-8847887 RAB33B:GTP binds RIC1:RGP1 TAS Homo sapiens 37565 R-HSA-8848618 https://reactome.org/PathwayBrowser/#/R-HSA-8848618 Activation of RAC1 by the PXN:CRK complex TAS Homo sapiens 37565 R-HSA-8849082 https://reactome.org/PathwayBrowser/#/R-HSA-8849082 ARHGAP35 stimulates RHOA GTPase activity TAS Homo sapiens 37565 R-HSA-8849085 https://reactome.org/PathwayBrowser/#/R-HSA-8849085 ARHGAP35 binds RHOA:GTP TAS Homo sapiens 37565 R-HSA-8849348 https://reactome.org/PathwayBrowser/#/R-HSA-8849348 RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo TAS Homo sapiens 37565 R-HSA-8849350 https://reactome.org/PathwayBrowser/#/R-HSA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex TAS Homo sapiens 37565 R-HSA-8849353 https://reactome.org/PathwayBrowser/#/R-HSA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER TAS Homo sapiens 37565 R-HSA-8849748 https://reactome.org/PathwayBrowser/#/R-HSA-8849748 The COG complex binds RABs at the Golgi membrane TAS Homo sapiens 37565 R-HSA-8850041 https://reactome.org/PathwayBrowser/#/R-HSA-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 TAS Homo sapiens 37565 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 37565 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 37565 R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 37565 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 37565 R-HSA-8851827 https://reactome.org/PathwayBrowser/#/R-HSA-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 TAS Homo sapiens 37565 R-HSA-8851877 https://reactome.org/PathwayBrowser/#/R-HSA-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET TAS Homo sapiens 37565 R-HSA-8851899 https://reactome.org/PathwayBrowser/#/R-HSA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET TAS Homo sapiens 37565 R-HSA-8852280 https://reactome.org/PathwayBrowser/#/R-HSA-8852280 GTSE1 binds microtubule lattice in interphase cells TAS Homo sapiens 37565 R-HSA-8852298 https://reactome.org/PathwayBrowser/#/R-HSA-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends TAS Homo sapiens 37565 R-HSA-8852306 https://reactome.org/PathwayBrowser/#/R-HSA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends TAS Homo sapiens 37565 R-HSA-8854173 https://reactome.org/PathwayBrowser/#/R-HSA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 TAS Homo sapiens 37565 R-HSA-8854182 https://reactome.org/PathwayBrowser/#/R-HSA-8854182 TBC1D17 binds OPTN:RAB8A TAS Homo sapiens 37565 R-HSA-8854293 https://reactome.org/PathwayBrowser/#/R-HSA-8854293 TBC1D10A (EPI64) binds ARF6:GTP TAS Homo sapiens 37565 R-HSA-8854303 https://reactome.org/PathwayBrowser/#/R-HSA-8854303 TBC1D11 binds RAB6 TAS Homo sapiens 37565 R-HSA-8854612 https://reactome.org/PathwayBrowser/#/R-HSA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B TAS Homo sapiens 37565 R-HSA-8856808 https://reactome.org/PathwayBrowser/#/R-HSA-8856808 Recruitment of AP-2 complex and clathrin TAS Homo sapiens 37565 R-HSA-8865774 https://reactome.org/PathwayBrowser/#/R-HSA-8865774 TTLLs polyglutamylate tubulin TAS Homo sapiens 37565 R-HSA-8866105 https://reactome.org/PathwayBrowser/#/R-HSA-8866105 CCPs deglutamylate tubulin IEA Homo sapiens 37565 R-HSA-8867370 https://reactome.org/PathwayBrowser/#/R-HSA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin TAS Homo sapiens 37565 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 37565 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 37565 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 37565 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 37565 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 37565 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 37565 R-HSA-8875318 https://reactome.org/PathwayBrowser/#/R-HSA-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A TAS Homo sapiens 37565 R-HSA-8875320 https://reactome.org/PathwayBrowser/#/R-HSA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 TAS Homo sapiens 37565 R-HSA-8875568 https://reactome.org/PathwayBrowser/#/R-HSA-8875568 RAPGEF1 activates RAP1 TAS Homo sapiens 37565 R-HSA-8875591 https://reactome.org/PathwayBrowser/#/R-HSA-8875591 DOCK7 activates RAC1 TAS Homo sapiens 37565 R-HSA-8875659 https://reactome.org/PathwayBrowser/#/R-HSA-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane TAS Homo sapiens 37565 R-HSA-8875661 https://reactome.org/PathwayBrowser/#/R-HSA-8875661 GGA3 associates with activated MET receptor TAS Homo sapiens 37565 R-HSA-8876188 https://reactome.org/PathwayBrowser/#/R-HSA-8876188 DENND4s exchange GTP for GDP on RAB10 TAS Homo sapiens 37565 R-HSA-8876190 https://reactome.org/PathwayBrowser/#/R-HSA-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 TAS Homo sapiens 37565 R-HSA-8876191 https://reactome.org/PathwayBrowser/#/R-HSA-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 TAS Homo sapiens 37565 R-HSA-8876193 https://reactome.org/PathwayBrowser/#/R-HSA-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 TAS Homo sapiens 37565 R-HSA-8876454 https://reactome.org/PathwayBrowser/#/R-HSA-8876454 DENND3 exchanges GTP for GDP on RAB12 TAS Homo sapiens 37565 R-HSA-8876615 https://reactome.org/PathwayBrowser/#/R-HSA-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 TAS Homo sapiens 37565 R-HSA-8876616 https://reactome.org/PathwayBrowser/#/R-HSA-8876616 DENND6A,B exchange GTP for GDP on RAB14 TAS Homo sapiens 37565 R-HSA-8876837 https://reactome.org/PathwayBrowser/#/R-HSA-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 TAS Homo sapiens 37565 R-HSA-8877308 https://reactome.org/PathwayBrowser/#/R-HSA-8877308 MADD exchanges GTP for GDP on RAB27 TAS Homo sapiens 37565 R-HSA-8877311 https://reactome.org/PathwayBrowser/#/R-HSA-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 TAS Homo sapiens 37565 R-HSA-8877451 https://reactome.org/PathwayBrowser/#/R-HSA-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 TAS Homo sapiens 37565 R-HSA-8877475 https://reactome.org/PathwayBrowser/#/R-HSA-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 TAS Homo sapiens 37565 R-HSA-8877612 https://reactome.org/PathwayBrowser/#/R-HSA-8877612 DENND1s exchange GTP for GDP on RAB35 TAS Homo sapiens 37565 R-HSA-8877760 https://reactome.org/PathwayBrowser/#/R-HSA-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 TAS Homo sapiens 37565 R-HSA-8877813 https://reactome.org/PathwayBrowser/#/R-HSA-8877813 DENND5A,B exchange GTP for GDP on RAB39 TAS Homo sapiens 37565 R-HSA-8877998 https://reactome.org/PathwayBrowser/#/R-HSA-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 TAS Homo sapiens 37565 R-HSA-8936676 https://reactome.org/PathwayBrowser/#/R-HSA-8936676 Moderate kinase activity BRAF mutants:RAS:GTP homo/heterodimerize TAS Homo sapiens 37565 R-HSA-8936731 https://reactome.org/PathwayBrowser/#/R-HSA-8936731 Inactive BRAF mutants:mutant RAS:GTP bind RAF1 TAS Homo sapiens 37565 R-HSA-8941613 https://reactome.org/PathwayBrowser/#/R-HSA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-8941618 https://reactome.org/PathwayBrowser/#/R-HSA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-8941623 https://reactome.org/PathwayBrowser/#/R-HSA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-8941628 https://reactome.org/PathwayBrowser/#/R-HSA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 37565 R-HSA-8944454 https://reactome.org/PathwayBrowser/#/R-HSA-8944454 mTORC1 phosphorylates MAF1 TAS Homo sapiens 37565 R-HSA-8944457 https://reactome.org/PathwayBrowser/#/R-HSA-8944457 MAF1 translocates to the nucleus TAS Homo sapiens 37565 R-HSA-8951490 https://reactome.org/PathwayBrowser/#/R-HSA-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 TAS Homo sapiens 37565 R-HSA-8951498 https://reactome.org/PathwayBrowser/#/R-HSA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex TAS Homo sapiens 37565 R-HSA-8951977 https://reactome.org/PathwayBrowser/#/R-HSA-8951977 Acetylated RUNX3 binds to BRD2 TAS Homo sapiens 37565 R-HSA-8952716 https://reactome.org/PathwayBrowser/#/R-HSA-8952716 SLC38A9 binds Ragulator:Rag dimers TAS Homo sapiens 37565 R-HSA-8952726 https://reactome.org/PathwayBrowser/#/R-HSA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol TAS Homo sapiens 37565 R-HSA-8955706 https://reactome.org/PathwayBrowser/#/R-HSA-8955706 TTL ligates L-Tyr to the carboxy terminus of detyr-alpha tubulin:beta tubulin IEA Homo sapiens 37565 R-HSA-8955712 https://reactome.org/PathwayBrowser/#/R-HSA-8955712 SVBP:VASH1,VASH2 hydrolyzes the terminal L-Tyr residue from alphaY-beta tubulin dimer IEA Homo sapiens 37565 R-HSA-8955869 https://reactome.org/PathwayBrowser/#/R-HSA-8955869 Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin IEA Homo sapiens 37565 R-HSA-8964242 https://reactome.org/PathwayBrowser/#/R-HSA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC TAS Homo sapiens 37565 R-HSA-8964246 https://reactome.org/PathwayBrowser/#/R-HSA-8964246 BTK in G alpha (12)-BTK complex is activated TAS Homo sapiens 37565 R-HSA-8964252 https://reactome.org/PathwayBrowser/#/R-HSA-8964252 G alpha (s):GTP:SRC catalyzes SRC to p-Y419-SRC TAS Homo sapiens 37565 R-HSA-8964274 https://reactome.org/PathwayBrowser/#/R-HSA-8964274 G alpha (12) binds BTK TAS Homo sapiens 37565 R-HSA-8964278 https://reactome.org/PathwayBrowser/#/R-HSA-8964278 G protein alpha (s):GTP binds SRC TAS Homo sapiens 37565 R-HSA-8964280 https://reactome.org/PathwayBrowser/#/R-HSA-8964280 Active Gq binds BTK TAS Homo sapiens 37565 R-HSA-8964284 https://reactome.org/PathwayBrowser/#/R-HSA-8964284 BTK in active Gq-BTK complex is activated TAS Homo sapiens 37565 R-HSA-8964287 https://reactome.org/PathwayBrowser/#/R-HSA-8964287 G alpha (s):GTP:SRC dissociates TAS Homo sapiens 37565 R-HSA-8964311 https://reactome.org/PathwayBrowser/#/R-HSA-8964311 G alpha (i):GTP binds SRC IEA Homo sapiens 37565 R-HSA-8964329 https://reactome.org/PathwayBrowser/#/R-HSA-8964329 G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC TAS Homo sapiens 37565 R-HSA-8964333 https://reactome.org/PathwayBrowser/#/R-HSA-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) TAS Homo sapiens 37565 R-HSA-8964340 https://reactome.org/PathwayBrowser/#/R-HSA-8964340 Gq-BTK complex dissociates to Active BTK and Gq TAS Homo sapiens 37565 R-HSA-8964599 https://reactome.org/PathwayBrowser/#/R-HSA-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex TAS Homo sapiens 37565 R-HSA-8964604 https://reactome.org/PathwayBrowser/#/R-HSA-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated TAS Homo sapiens 37565 R-HSA-8964614 https://reactome.org/PathwayBrowser/#/R-HSA-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated TAS Homo sapiens 37565 R-HSA-8980691 https://reactome.org/PathwayBrowser/#/R-HSA-8980691 RHOA GEFs activate RHOA TAS Homo sapiens 37565 R-HSA-8981353 https://reactome.org/PathwayBrowser/#/R-HSA-8981353 RASA1 stimulates RAS GTPase activity TAS Homo sapiens 37565 R-HSA-8981355 https://reactome.org/PathwayBrowser/#/R-HSA-8981355 RASA1 binds RAS:GTP TAS Homo sapiens 37565 R-HSA-8981443 https://reactome.org/PathwayBrowser/#/R-HSA-8981443 CIT-3 binds activated RHOA, RHOB, RHOC and RAC1 IEA Homo sapiens 37565 R-HSA-8981637 https://reactome.org/PathwayBrowser/#/R-HSA-8981637 RHOA GAPs stimulate RHOA GTPase activity TAS Homo sapiens 37565 R-HSA-8981892 https://reactome.org/PathwayBrowser/#/R-HSA-8981892 Active G alpha (z) binds RGS proteins TAS Homo sapiens 37565 R-HSA-8981926 https://reactome.org/PathwayBrowser/#/R-HSA-8981926 RAC1 and CDC42 activate PAK3 TAS Homo sapiens 37565 R-HSA-8981931 https://reactome.org/PathwayBrowser/#/R-HSA-8981931 RAC1 and CDC42 activate PAK2 TAS Homo sapiens 37565 R-HSA-8982017 https://reactome.org/PathwayBrowser/#/R-HSA-8982017 Active G alpha (q) binds RGS proteins TAS Homo sapiens 37565 R-HSA-8982019 https://reactome.org/PathwayBrowser/#/R-HSA-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins TAS Homo sapiens 37565 R-HSA-8982020 https://reactome.org/PathwayBrowser/#/R-HSA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated TAS Homo sapiens 37565 R-HSA-8982021 https://reactome.org/PathwayBrowser/#/R-HSA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated TAS Homo sapiens 37565 R-HSA-8982025 https://reactome.org/PathwayBrowser/#/R-HSA-8982025 G alpha (q) in G (q):RGS complex is inactivated TAS Homo sapiens 37565 R-HSA-8982640 https://reactome.org/PathwayBrowser/#/R-HSA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) TAS Homo sapiens 37565 R-HSA-8982703 https://reactome.org/PathwayBrowser/#/R-HSA-8982703 PKC binds active G alpha (z) IEA Homo sapiens 37565 R-HSA-8982709 https://reactome.org/PathwayBrowser/#/R-HSA-8982709 G-alpha(z):PKC dissociates to give phosphorylated G alpha (z) IEA Homo sapiens 37565 R-HSA-8985594 https://reactome.org/PathwayBrowser/#/R-HSA-8985594 MYO9B inactivates RHOA TAS Homo sapiens 37565 R-HSA-9013004 https://reactome.org/PathwayBrowser/#/R-HSA-9013004 RHOA binds effectors at the ER membrane TAS Homo sapiens 37565 R-HSA-9013006 https://reactome.org/PathwayBrowser/#/R-HSA-9013006 RHOA:GTP translocates to the ER membrane TAS Homo sapiens 37565 R-HSA-9013009 https://reactome.org/PathwayBrowser/#/R-HSA-9013009 RHOA binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9013022 https://reactome.org/PathwayBrowser/#/R-HSA-9013022 RHOB GAPs stimulate RHOB GTPase activity TAS Homo sapiens 37565 R-HSA-9013023 https://reactome.org/PathwayBrowser/#/R-HSA-9013023 RHOB GEFs activate RHOB TAS Homo sapiens 37565 R-HSA-9013024 https://reactome.org/PathwayBrowser/#/R-HSA-9013024 RHOB binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9013109 https://reactome.org/PathwayBrowser/#/R-HSA-9013109 RHOC GEFs activate RHOC TAS Homo sapiens 37565 R-HSA-9013110 https://reactome.org/PathwayBrowser/#/R-HSA-9013110 RHOC binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9013111 https://reactome.org/PathwayBrowser/#/R-HSA-9013111 RHOC GAPs stimulate RHOC GTPase activity TAS Homo sapiens 37565 R-HSA-9013143 https://reactome.org/PathwayBrowser/#/R-HSA-9013143 RAC1 GEFs activate RAC1 TAS Homo sapiens 37565 R-HSA-9013144 https://reactome.org/PathwayBrowser/#/R-HSA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity TAS Homo sapiens 37565 R-HSA-9013145 https://reactome.org/PathwayBrowser/#/R-HSA-9013145 RAC1 binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9013157 https://reactome.org/PathwayBrowser/#/R-HSA-9013157 CDC42 binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9013159 https://reactome.org/PathwayBrowser/#/R-HSA-9013159 CDC42 GEFs activate CDC42 TAS Homo sapiens 37565 R-HSA-9013161 https://reactome.org/PathwayBrowser/#/R-HSA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity TAS Homo sapiens 37565 R-HSA-9013435 https://reactome.org/PathwayBrowser/#/R-HSA-9013435 RHOD auto-activates TAS Homo sapiens 37565 R-HSA-9013437 https://reactome.org/PathwayBrowser/#/R-HSA-9013437 RHOD GAPs stimulate RHOD GTPase activity TAS Homo sapiens 37565 R-HSA-9013438 https://reactome.org/PathwayBrowser/#/R-HSA-9013438 RHOD binds effectors at the endosome membrane TAS Homo sapiens 37565 R-HSA-9013452 https://reactome.org/PathwayBrowser/#/R-HSA-9013452 RHOD:GTP translocates to the endosome membrane TAS Homo sapiens 37565 R-HSA-9014294 https://reactome.org/PathwayBrowser/#/R-HSA-9014294 RAC2 binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9014295 https://reactome.org/PathwayBrowser/#/R-HSA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity TAS Homo sapiens 37565 R-HSA-9014296 https://reactome.org/PathwayBrowser/#/R-HSA-9014296 RAC2 GEFs activate RAC2 TAS Homo sapiens 37565 R-HSA-9014420 https://reactome.org/PathwayBrowser/#/R-HSA-9014420 RAC2 translocates to the phagocytic vesicle membrane TAS Homo sapiens 37565 R-HSA-9014424 https://reactome.org/PathwayBrowser/#/R-HSA-9014424 RAC2 binds effectors at the phagocytic vesicle membrane TAS Homo sapiens 37565 R-HSA-9014433 https://reactome.org/PathwayBrowser/#/R-HSA-9014433 RHOG GEFs activate RHOG TAS Homo sapiens 37565 R-HSA-9014434 https://reactome.org/PathwayBrowser/#/R-HSA-9014434 RHOG GAPs stimulate RHOG GTPase activity TAS Homo sapiens 37565 R-HSA-9014449 https://reactome.org/PathwayBrowser/#/R-HSA-9014449 RHOG binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9014454 https://reactome.org/PathwayBrowser/#/R-HSA-9014454 RHOG translocates to the ER membrane TAS Homo sapiens 37565 R-HSA-9014467 https://reactome.org/PathwayBrowser/#/R-HSA-9014467 RHOG binds effectors at the ER membrane TAS Homo sapiens 37565 R-HSA-9017488 https://reactome.org/PathwayBrowser/#/R-HSA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity TAS Homo sapiens 37565 R-HSA-9017491 https://reactome.org/PathwayBrowser/#/R-HSA-9017491 RHOJ GEFs activate RHOJ TAS Homo sapiens 37565 R-HSA-9017507 https://reactome.org/PathwayBrowser/#/R-HSA-9017507 RHOJ binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9018745 https://reactome.org/PathwayBrowser/#/R-HSA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity TAS Homo sapiens 37565 R-HSA-9018746 https://reactome.org/PathwayBrowser/#/R-HSA-9018746 RHOQ binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9018747 https://reactome.org/PathwayBrowser/#/R-HSA-9018747 RHOQ GEFs activate RHOQ TAS Homo sapiens 37565 R-HSA-9018754 https://reactome.org/PathwayBrowser/#/R-HSA-9018754 GDIs bind RHOH TAS Homo sapiens 37565 R-HSA-9018756 https://reactome.org/PathwayBrowser/#/R-HSA-9018756 RHOH binds GTP TAS Homo sapiens 37565 R-HSA-9018758 https://reactome.org/PathwayBrowser/#/R-HSA-9018758 RHOH binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9018766 https://reactome.org/PathwayBrowser/#/R-HSA-9018766 RHOU binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9018768 https://reactome.org/PathwayBrowser/#/R-HSA-9018768 RHOU auto-activates TAS Homo sapiens 37565 R-HSA-9018774 https://reactome.org/PathwayBrowser/#/R-HSA-9018774 RHOBTB1 binds GTP TAS Homo sapiens 37565 R-HSA-9018778 https://reactome.org/PathwayBrowser/#/R-HSA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane TAS Homo sapiens 37565 R-HSA-9018785 https://reactome.org/PathwayBrowser/#/R-HSA-9018785 RHOBTB2 binds GTP TAS Homo sapiens 37565 R-HSA-9018787 https://reactome.org/PathwayBrowser/#/R-HSA-9018787 RHOBTB2 binds interacting proteins at the endosome membrane TAS Homo sapiens 37565 R-HSA-9018794 https://reactome.org/PathwayBrowser/#/R-HSA-9018794 RHOV binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9018798 https://reactome.org/PathwayBrowser/#/R-HSA-9018798 RHOV binds GTP TAS Homo sapiens 37565 R-HSA-9018804 https://reactome.org/PathwayBrowser/#/R-HSA-9018804 RAC3 GEFs activate RAC3 TAS Homo sapiens 37565 R-HSA-9018806 https://reactome.org/PathwayBrowser/#/R-HSA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity TAS Homo sapiens 37565 R-HSA-9018808 https://reactome.org/PathwayBrowser/#/R-HSA-9018808 RAC3 binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9018814 https://reactome.org/PathwayBrowser/#/R-HSA-9018814 RHOT1 hydrolyzes GTP TAS Homo sapiens 37565 R-HSA-9018815 https://reactome.org/PathwayBrowser/#/R-HSA-9018815 RHOT1 binds effectors at the mitochondrial outer membrane TAS Homo sapiens 37565 R-HSA-9018817 https://reactome.org/PathwayBrowser/#/R-HSA-9018817 RHOT1 GEFs activate RHOT1 IEA Homo sapiens 37565 R-HSA-9018824 https://reactome.org/PathwayBrowser/#/R-HSA-9018824 RHOT2 binds effectors at the mitochondrial outer membrane TAS Homo sapiens 37565 R-HSA-9018825 https://reactome.org/PathwayBrowser/#/R-HSA-9018825 RHOT2 GEFs activate RHOT2 IEA Homo sapiens 37565 R-HSA-9018826 https://reactome.org/PathwayBrowser/#/R-HSA-9018826 RHOT2 hydrolyzes GTP TAS Homo sapiens 37565 R-HSA-9018836 https://reactome.org/PathwayBrowser/#/R-HSA-9018836 RHOQ translocates to the Golgi-associated vesicle membranes TAS Homo sapiens 37565 R-HSA-9026891 https://reactome.org/PathwayBrowser/#/R-HSA-9026891 NTRK2 activates RAS signaling through SHC1 IEA Homo sapiens 37565 R-HSA-9029158 https://reactome.org/PathwayBrowser/#/R-HSA-9029158 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:GRB2-1:SOS1,phospho-VAV1 mediates exchange of GTP for GDP bound to RAS IEA Homo sapiens 37565 R-HSA-9032067 https://reactome.org/PathwayBrowser/#/R-HSA-9032067 NTRK2 activates RAS signaling through FRS2 IEA Homo sapiens 37565 R-HSA-9032798 https://reactome.org/PathwayBrowser/#/R-HSA-9032798 DOCK3 activates RAC1 TAS Homo sapiens 37565 R-HSA-9033292 https://reactome.org/PathwayBrowser/#/R-HSA-9033292 NTRK2 and CDK5 promote activation of RAC1 by TIAM1 IEA Homo sapiens 37565 R-HSA-9036301 https://reactome.org/PathwayBrowser/#/R-HSA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s TAS Homo sapiens 37565 R-HSA-9036308 https://reactome.org/PathwayBrowser/#/R-HSA-9036308 ESTG-stimulated dissociation of GPER:heterotrimeric G-protein (s) complex TAS Homo sapiens 37565 R-HSA-9036970 https://reactome.org/PathwayBrowser/#/R-HSA-9036970 NTRK3 activates RAS through SHC1 IEA Homo sapiens 37565 R-HSA-939265 https://reactome.org/PathwayBrowser/#/R-HSA-939265 Activation of Rap1 by membrane-associated GEFs TAS Homo sapiens 37565 R-HSA-947535 https://reactome.org/PathwayBrowser/#/R-HSA-947535 Cyclisation of GTP to precursor Z TAS Homo sapiens 37565 R-HSA-9607304 https://reactome.org/PathwayBrowser/#/R-HSA-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 TAS Homo sapiens 37565 R-HSA-9610152 https://reactome.org/PathwayBrowser/#/R-HSA-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome TAS Homo sapiens 37565 R-HSA-9610153 https://reactome.org/PathwayBrowser/#/R-HSA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF TAS Homo sapiens 37565 R-HSA-9610154 https://reactome.org/PathwayBrowser/#/R-HSA-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs TAS Homo sapiens 37565 R-HSA-9610156 https://reactome.org/PathwayBrowser/#/R-HSA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF TAS Homo sapiens 37565 R-HSA-9610163 https://reactome.org/PathwayBrowser/#/R-HSA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF TAS Homo sapiens 37565 R-HSA-9610408 https://reactome.org/PathwayBrowser/#/R-HSA-9610408 GluN1:GluN2B (GRIN1:GRIN2B) di-heterotetramers bind LIN7:CASK:APBA1, DLG1 and KIF17 IEA Homo sapiens 37565 R-HSA-9610627 https://reactome.org/PathwayBrowser/#/R-HSA-9610627 KIF17 transports GluN1:GluN2B (GRIN1:GRIN2B) NMDA receptors to the plasma membrane IEA Homo sapiens 37565 R-HSA-9612980 https://reactome.org/PathwayBrowser/#/R-HSA-9612980 BRAF in Rap1-GTP complex:BRAF complex autophosphorylates IEA Homo sapiens 37565 R-HSA-9614343 https://reactome.org/PathwayBrowser/#/R-HSA-9614343 Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs TAS Homo sapiens 37565 R-HSA-9614367 https://reactome.org/PathwayBrowser/#/R-HSA-9614367 HCMV Nuclear Pore Docking TAS Homo sapiens 37565 R-HSA-9615945 https://reactome.org/PathwayBrowser/#/R-HSA-9615945 RAN:GTP binds TNPO1/KPNB1 (transportin/importin beta) associated with the Nup107-160 complex and releases Nup107-160 IEA Homo sapiens 37565 R-HSA-9619542 https://reactome.org/PathwayBrowser/#/R-HSA-9619542 AMPK negatively regulates binding of MAPT to microtubules IEA Homo sapiens 37565 R-HSA-9619803 https://reactome.org/PathwayBrowser/#/R-HSA-9619803 p-S516-ARHGEF7 activates RAC1 IEA Homo sapiens 37565 R-HSA-9624845 https://reactome.org/PathwayBrowser/#/R-HSA-9624845 RCC1 stimulates GDP to GTP exchange on RAN TAS Homo sapiens 37565 R-HSA-9624876 https://reactome.org/PathwayBrowser/#/R-HSA-9624876 RAN:GTP recruits nuclear envelope (NE) membranes TAS Homo sapiens 37565 R-HSA-9624893 https://reactome.org/PathwayBrowser/#/R-HSA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes TAS Homo sapiens 37565 R-HSA-9626038 https://reactome.org/PathwayBrowser/#/R-HSA-9626038 EEF1A1 binds GTP IEA Homo sapiens 37565 R-HSA-9626067 https://reactome.org/PathwayBrowser/#/R-HSA-9626067 EEF1A1:GTP translocates from lysosomal membrane to cytosol IEA Homo sapiens 37565 R-HSA-9626848 https://reactome.org/PathwayBrowser/#/R-HSA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex TAS Homo sapiens 37565 R-HSA-9632910 https://reactome.org/PathwayBrowser/#/R-HSA-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus TAS Homo sapiens 37565 R-HSA-9632918 https://reactome.org/PathwayBrowser/#/R-HSA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen TAS Homo sapiens 37565 R-HSA-9634418 https://reactome.org/PathwayBrowser/#/R-HSA-9634418 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and ERBB2 homodimer:p-SHC1 TAS Homo sapiens 37565 R-HSA-9636684 https://reactome.org/PathwayBrowser/#/R-HSA-9636684 ndkA dephosphorylates RAB5A:GTP,RAB7A:GTP TAS Homo sapiens 37565 R-HSA-9639286 https://reactome.org/PathwayBrowser/#/R-HSA-9639286 RRAGC,D exchanges GTP for GDP TAS Homo sapiens 37565 R-HSA-9640167 https://reactome.org/PathwayBrowser/#/R-HSA-9640167 RRAGA,B exchanges GDP for GTP TAS Homo sapiens 37565 R-HSA-9640168 https://reactome.org/PathwayBrowser/#/R-HSA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine TAS Homo sapiens 37565 R-HSA-9640195 https://reactome.org/PathwayBrowser/#/R-HSA-9640195 RRAGA,B hydrolyzes GTP TAS Homo sapiens 37565 R-HSA-9645598 https://reactome.org/PathwayBrowser/#/R-HSA-9645598 RRAGC,D hydrolyzes GTP TAS Homo sapiens 37565 R-HSA-9645608 https://reactome.org/PathwayBrowser/#/R-HSA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 TAS Homo sapiens 37565 R-HSA-9646383 https://reactome.org/PathwayBrowser/#/R-HSA-9646383 Dynein motors transport misfolded proteins IEA Homo sapiens 37565 R-HSA-9646390 https://reactome.org/PathwayBrowser/#/R-HSA-9646390 Misfolded proteins:HDAC6:Dynein motor binds microtubule IEA Homo sapiens 37565 R-HSA-9646468 https://reactome.org/PathwayBrowser/#/R-HSA-9646468 mTORC1 binds RHEB:GTP TAS Homo sapiens 37565 R-HSA-9646679 https://reactome.org/PathwayBrowser/#/R-HSA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome TAS Homo sapiens 37565 R-HSA-9646685 https://reactome.org/PathwayBrowser/#/R-HSA-9646685 Aggresome dissociates from dynein and microtubule TAS Homo sapiens 37565 R-HSA-9648017 https://reactome.org/PathwayBrowser/#/R-HSA-9648017 EML4 binds to microtubules TAS Homo sapiens 37565 R-HSA-9648114 https://reactome.org/PathwayBrowser/#/R-HSA-9648114 EML4 recruits NUDC to mitotic spindle TAS Homo sapiens 37565 R-HSA-9649735 https://reactome.org/PathwayBrowser/#/R-HSA-9649735 Intrinsic nucleotide exchange on RAS TAS Homo sapiens 37565 R-HSA-9649736 https://reactome.org/PathwayBrowser/#/R-HSA-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP TAS Homo sapiens 37565 R-HSA-9651280 https://reactome.org/PathwayBrowser/#/R-HSA-9651280 RAS GAP mutants aren't stimulated by GAPs TAS Homo sapiens 37565 R-HSA-9653108 https://reactome.org/PathwayBrowser/#/R-HSA-9653108 Raf dimer inhibitors bind RAF heterodimers TAS Homo sapiens 37565 R-HSA-9654523 https://reactome.org/PathwayBrowser/#/R-HSA-9654523 ARL2:GTP bind PDE6D on KRAS4B TAS Homo sapiens 37565 R-HSA-9654533 https://reactome.org/PathwayBrowser/#/R-HSA-9654533 KRAS4B recycles to the plasma membrane TAS Homo sapiens 37565 R-HSA-9656209 https://reactome.org/PathwayBrowser/#/R-HSA-9656209 Dissociation of RAS:RAF1 mutant complex TAS Homo sapiens 37565 R-HSA-9656211 https://reactome.org/PathwayBrowser/#/R-HSA-9656211 MAP2Ks and MAPKs bind to the activated mutant RAF1 complex TAS Homo sapiens 37565 R-HSA-9656212 https://reactome.org/PathwayBrowser/#/R-HSA-9656212 Phosphorylation of RAF1 mutants TAS Homo sapiens 37565 R-HSA-9656213 https://reactome.org/PathwayBrowser/#/R-HSA-9656213 RAF1 mutants show enhanced heterodimerization with BRAF TAS Homo sapiens 37565 R-HSA-9656214 https://reactome.org/PathwayBrowser/#/R-HSA-9656214 MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants TAS Homo sapiens 37565 R-HSA-9656215 https://reactome.org/PathwayBrowser/#/R-HSA-9656215 RAF1 mutant complexes phosphorylate MAP2K dimer TAS Homo sapiens 37565 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 37565 R-HSA-9657603 https://reactome.org/PathwayBrowser/#/R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs TAS Homo sapiens 37565 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 37565 R-HSA-9657608 https://reactome.org/PathwayBrowser/#/R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK TAS Homo sapiens 37565 R-HSA-9658253 https://reactome.org/PathwayBrowser/#/R-HSA-9658253 RAS:GTP binds PI3K TAS Homo sapiens 37565 R-HSA-9658445 https://reactome.org/PathwayBrowser/#/R-HSA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs TAS Homo sapiens 37565 R-HSA-9660536 https://reactome.org/PathwayBrowser/#/R-HSA-9660536 SHOC2 M173I disrupts the SHOC2:MRAS:PP1 complex TAS Homo sapiens 37565 R-HSA-9660538 https://reactome.org/PathwayBrowser/#/R-HSA-9660538 Mutant MRAS:SHOC2:PPP1CC complexes dephosphorylate inactive RAFs TAS Homo sapiens 37565 R-HSA-9660557 https://reactome.org/PathwayBrowser/#/R-HSA-9660557 RAS:GTP binds RAL GDS proteins TAS Homo sapiens 37565 R-HSA-9660819 https://reactome.org/PathwayBrowser/#/R-HSA-9660819 ADORA2B:Ade-Rib:GsGTP dissociates TAS Homo sapiens 37565 R-HSA-9660824 https://reactome.org/PathwayBrowser/#/R-HSA-9660824 ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs TAS Homo sapiens 37565 R-HSA-9664991 https://reactome.org/PathwayBrowser/#/R-HSA-9664991 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants TAS Homo sapiens 37565 R-HSA-9665009 https://reactome.org/PathwayBrowser/#/R-HSA-9665009 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR TAS Homo sapiens 37565 R-HSA-9665404 https://reactome.org/PathwayBrowser/#/R-HSA-9665404 RAS guanyl nucleotide exchange mediated by the p-6Y- ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-SHC1:GRB2:SOS1 TAS Homo sapiens 37565 R-HSA-9665408 https://reactome.org/PathwayBrowser/#/R-HSA-9665408 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR through GRB2 TAS Homo sapiens 37565 R-HSA-9665700 https://reactome.org/PathwayBrowser/#/R-HSA-9665700 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants TAS Homo sapiens 37565 R-HSA-9665707 https://reactome.org/PathwayBrowser/#/R-HSA-9665707 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR TAS Homo sapiens 37565 R-HSA-9666428 https://reactome.org/PathwayBrowser/#/R-HSA-9666428 DOCK180 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens 37565 R-HSA-9666430 https://reactome.org/PathwayBrowser/#/R-HSA-9666430 p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens 37565 R-HSA-9668419 https://reactome.org/PathwayBrowser/#/R-HSA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites TAS Homo sapiens 37565 R-HSA-9670155 https://reactome.org/PathwayBrowser/#/R-HSA-9670155 CDC42:GTP binds PtdIns(4,5)P2:WASP,N-WASP IEA Homo sapiens 37565 R-HSA-9670436 https://reactome.org/PathwayBrowser/#/R-HSA-9670436 p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS TAS Homo sapiens 37565 R-HSA-9672163 https://reactome.org/PathwayBrowser/#/R-HSA-9672163 SOS-mediated nucleotide exchange on RAS downstream of PDGFRA extracellular domain dimers TAS Homo sapiens 37565 R-HSA-9672170 https://reactome.org/PathwayBrowser/#/R-HSA-9672170 SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors TAS Homo sapiens 37565 R-HSA-9673284 https://reactome.org/PathwayBrowser/#/R-HSA-9673284 GTP-bound RAC1 contributes to MAPK8 activation TAS Homo sapiens 37565 R-HSA-9673288 https://reactome.org/PathwayBrowser/#/R-HSA-9673288 ppDVL binds RAC1:GTP TAS Homo sapiens 37565 R-HSA-9673794 https://reactome.org/PathwayBrowser/#/R-HSA-9673794 ppDVL:RAC1:GTP binds NOX1 complex TAS Homo sapiens 37565 R-HSA-9673797 https://reactome.org/PathwayBrowser/#/R-HSA-9673797 NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 37565 R-HSA-9680385 https://reactome.org/PathwayBrowser/#/R-HSA-9680385 CSF1R-associated SOS1 mediates exchange of GTP for GDP bound to RAS IEA Homo sapiens 37565 R-HSA-9684016 https://reactome.org/PathwayBrowser/#/R-HSA-9684016 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 37565 R-HSA-9684017 https://reactome.org/PathwayBrowser/#/R-HSA-9684017 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 37565 R-HSA-9684018 https://reactome.org/PathwayBrowser/#/R-HSA-9684018 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 37565 R-HSA-9690493 https://reactome.org/PathwayBrowser/#/R-HSA-9690493 RHOB binds effectors on endosomes TAS Homo sapiens 37565 R-HSA-9690494 https://reactome.org/PathwayBrowser/#/R-HSA-9690494 RHOB translocates to the endosome membrane TAS Homo sapiens 37565 R-HSA-9691168 https://reactome.org/PathwayBrowser/#/R-HSA-9691168 RAC1 translocates to the endoplasmic reticulum membrane TAS Homo sapiens 37565 R-HSA-9691174 https://reactome.org/PathwayBrowser/#/R-HSA-9691174 RAC1 binds effectors at the ER membrane TAS Homo sapiens 37565 R-HSA-9692800 https://reactome.org/PathwayBrowser/#/R-HSA-9692800 CDC42 translocates to the endoplasmic reticulum membrane TAS Homo sapiens 37565 R-HSA-9692809 https://reactome.org/PathwayBrowser/#/R-HSA-9692809 CDC42 binds effectors at the ER membrane TAS Homo sapiens 37565 R-HSA-9693111 https://reactome.org/PathwayBrowser/#/R-HSA-9693111 RHOF auto-activates TAS Homo sapiens 37565 R-HSA-9693125 https://reactome.org/PathwayBrowser/#/R-HSA-9693125 RHOF binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9693198 https://reactome.org/PathwayBrowser/#/R-HSA-9693198 RHOD binds effectors at the plasma membrane TAS Homo sapiens 37565 R-HSA-9693207 https://reactome.org/PathwayBrowser/#/R-HSA-9693207 RHOD translocates to the mitochondrial outer membrane TAS Homo sapiens 37565 R-HSA-9693214 https://reactome.org/PathwayBrowser/#/R-HSA-9693214 RHOD binds effectors at the mitochondrial outer membrane TAS Homo sapiens 37565 R-HSA-9693243 https://reactome.org/PathwayBrowser/#/R-HSA-9693243 RHOD translocates to the Golgi membrane TAS Homo sapiens 37565 R-HSA-9693250 https://reactome.org/PathwayBrowser/#/R-HSA-9693250 RHOD binds effectors at the Golgi membrane TAS Homo sapiens 37565 R-HSA-9693282 https://reactome.org/PathwayBrowser/#/R-HSA-9693282 RHOF GAPs stimulate RHOF GTPase activity TAS Homo sapiens 37565 R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 37565 R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 37565 R-HSA-9695853 https://reactome.org/PathwayBrowser/#/R-HSA-9695853 FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS TAS Homo sapiens 37565 R-HSA-9696266 https://reactome.org/PathwayBrowser/#/R-HSA-9696266 RND2 binds effectors TAS Homo sapiens 37565 R-HSA-9696267 https://reactome.org/PathwayBrowser/#/R-HSA-9696267 RND3 binds GTP TAS Homo sapiens 37565 R-HSA-9696268 https://reactome.org/PathwayBrowser/#/R-HSA-9696268 RND3 binds effectors TAS Homo sapiens 37565 R-HSA-9696271 https://reactome.org/PathwayBrowser/#/R-HSA-9696271 RND1 binds effectors TAS Homo sapiens 37565 R-HSA-9696274 https://reactome.org/PathwayBrowser/#/R-HSA-9696274 RND1 binds GTP TAS Homo sapiens 37565 R-HSA-9696275 https://reactome.org/PathwayBrowser/#/R-HSA-9696275 RND2 binds GTP TAS Homo sapiens 37565 R-HSA-9703441 https://reactome.org/PathwayBrowser/#/R-HSA-9703441 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 fusion mutants TAS Homo sapiens 37565 R-HSA-9712183 https://reactome.org/PathwayBrowser/#/R-HSA-9712183 ADCY3:GNAL:GTP converts ATP to cAMP IEA Homo sapiens 37565 R-HSA-9712187 https://reactome.org/PathwayBrowser/#/R-HSA-9712187 GNAL:GTP (G alpha-olf) binds ADCY3 IEA Homo sapiens 37565 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 37565 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 37565 R-HSA-9714361 https://reactome.org/PathwayBrowser/#/R-HSA-9714361 RHOC activates endoplasmic reticulum effectors TAS Homo sapiens 37565 R-HSA-9714363 https://reactome.org/PathwayBrowser/#/R-HSA-9714363 RHOC translocates to the endoplasmic reticulum membrane TAS Homo sapiens 37565 R-HSA-9714477 https://reactome.org/PathwayBrowser/#/R-HSA-9714477 RAC2 binds effectors at the mitochondrial outer membrane TAS Homo sapiens 37565 R-HSA-9714480 https://reactome.org/PathwayBrowser/#/R-HSA-9714480 RAC2 translocates to the mitochondrial membrane TAS Homo sapiens 37565 R-HSA-9714481 https://reactome.org/PathwayBrowser/#/R-HSA-9714481 RAC2 binds effectors at the ER membrane TAS Homo sapiens 37565 R-HSA-9714483 https://reactome.org/PathwayBrowser/#/R-HSA-9714483 RAC2 translocates to the ER membrane TAS Homo sapiens 37565 R-HSA-9714691 https://reactome.org/PathwayBrowser/#/R-HSA-9714691 RAC3 binds ER effectors TAS Homo sapiens 37565 R-HSA-9714694 https://reactome.org/PathwayBrowser/#/R-HSA-9714694 RAC3 translocates to the endoplasmic reticulum membrane TAS Homo sapiens 37565 R-HSA-9717182 https://reactome.org/PathwayBrowser/#/R-HSA-9717182 L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP and GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 37565 R-HSA-9717202 https://reactome.org/PathwayBrowser/#/R-HSA-9717202 GNAT3 exchanges GDP for GTP in L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 37565 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 37565 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 37565 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 37565 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 37565 R-HSA-9765952 https://reactome.org/PathwayBrowser/#/R-HSA-9765952 nsp12 guanylates nsp7 TAS Homo sapiens 37565 R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 37565 R-HSA-9830848 https://reactome.org/PathwayBrowser/#/R-HSA-9830848 L protein acts as a cap N7 methyltransferase to modify RSV mRNAs TAS Homo sapiens 37565 R-HSA-983259 https://reactome.org/PathwayBrowser/#/R-HSA-983259 Kinesins move along microtubules consuming ATP TAS Homo sapiens 37565 R-HSA-983266 https://reactome.org/PathwayBrowser/#/R-HSA-983266 Kinesins bind microtubules TAS Homo sapiens 37565 R-HSA-983422 https://reactome.org/PathwayBrowser/#/R-HSA-983422 Disassembly of COPII coated vesicle TAS Homo sapiens 37565 R-HSA-983424 https://reactome.org/PathwayBrowser/#/R-HSA-983424 Budding of COPII coated vesicle TAS Homo sapiens 37565 R-HSA-983425 https://reactome.org/PathwayBrowser/#/R-HSA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle TAS Homo sapiens 37565 R-HSA-983426 https://reactome.org/PathwayBrowser/#/R-HSA-983426 Capturing cargo and formation of prebudding complex TAS Homo sapiens 37565 R-HSA-9836404 https://reactome.org/PathwayBrowser/#/R-HSA-9836404 p-PKR dimer phosphorylates MAPT TAS Homo sapiens 37565 R-MMU-1008248 https://reactome.org/PathwayBrowser/#/R-MMU-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Mus musculus 37565 R-MMU-111519 https://reactome.org/PathwayBrowser/#/R-MMU-111519 inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate TAS Mus musculus 37565 R-MMU-111524 https://reactome.org/PathwayBrowser/#/R-MMU-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Mus musculus 37565 R-MMU-111879 https://reactome.org/PathwayBrowser/#/R-MMU-111879 PIP2 hydrolysis IEA Mus musculus 37565 R-MMU-112037 https://reactome.org/PathwayBrowser/#/R-MMU-112037 Inactivation of PLC beta IEA Mus musculus 37565 R-MMU-112271 https://reactome.org/PathwayBrowser/#/R-MMU-112271 The receptor:G-protein complex dissociates IEA Mus musculus 37565 R-MMU-114542 https://reactome.org/PathwayBrowser/#/R-MMU-114542 RAC1,RAC2,RHOG activate PI3K IEA Mus musculus 37565 R-MMU-114544 https://reactome.org/PathwayBrowser/#/R-MMU-114544 p115-RhoGEF activation of RHOA IEA Mus musculus 37565 R-MMU-114548 https://reactome.org/PathwayBrowser/#/R-MMU-114548 G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) IEA Mus musculus 37565 R-MMU-114552 https://reactome.org/PathwayBrowser/#/R-MMU-114552 Thrombin-activated PARs activate G12/13 IEA Mus musculus 37565 R-MMU-114558 https://reactome.org/PathwayBrowser/#/R-MMU-114558 Thrombin-activated PARs activate Gq IEA Mus musculus 37565 R-MMU-114688 https://reactome.org/PathwayBrowser/#/R-MMU-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Mus musculus 37565 R-MMU-1168636 https://reactome.org/PathwayBrowser/#/R-MMU-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Mus musculus 37565 R-MMU-1250383 https://reactome.org/PathwayBrowser/#/R-MMU-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Mus musculus 37565 R-MMU-1306972 https://reactome.org/PathwayBrowser/#/R-MMU-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Mus musculus 37565 R-MMU-1433415 https://reactome.org/PathwayBrowser/#/R-MMU-1433415 Activation of RAC1 IEA Mus musculus 37565 R-MMU-1433471 https://reactome.org/PathwayBrowser/#/R-MMU-1433471 Activation of RAS by p-KIT bound SOS1 IEA Mus musculus 37565 R-MMU-1449633 https://reactome.org/PathwayBrowser/#/R-MMU-1449633 Rab8a/10/13/14 Hydrolyze GTP TAS Mus musculus 37565 R-MMU-1474146 https://reactome.org/PathwayBrowser/#/R-MMU-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Mus musculus 37565 R-MMU-156808 https://reactome.org/PathwayBrowser/#/R-MMU-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Mus musculus 37565 R-MMU-156823 https://reactome.org/PathwayBrowser/#/R-MMU-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Mus musculus 37565 R-MMU-156913 https://reactome.org/PathwayBrowser/#/R-MMU-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Mus musculus 37565 R-MMU-156930 https://reactome.org/PathwayBrowser/#/R-MMU-156930 GTP-binding activates eEF2 IEA Mus musculus 37565 R-MMU-157849 https://reactome.org/PathwayBrowser/#/R-MMU-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Mus musculus 37565 R-MMU-1638803 https://reactome.org/PathwayBrowser/#/R-MMU-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Mus musculus 37565 R-MMU-1638821 https://reactome.org/PathwayBrowser/#/R-MMU-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Mus musculus 37565 R-MMU-165195 https://reactome.org/PathwayBrowser/#/R-MMU-165195 GTP loading by Rheb IEA Mus musculus 37565 R-MMU-165680 https://reactome.org/PathwayBrowser/#/R-MMU-165680 Formation of active mTORC1 complex IEA Mus musculus 37565 R-MMU-165692 https://reactome.org/PathwayBrowser/#/R-MMU-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Mus musculus 37565 R-MMU-165718 https://reactome.org/PathwayBrowser/#/R-MMU-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Mus musculus 37565 R-MMU-167415 https://reactome.org/PathwayBrowser/#/R-MMU-167415 G-protein alpha subunit is inactivated IEA Mus musculus 37565 R-MMU-167429 https://reactome.org/PathwayBrowser/#/R-MMU-167429 The receptor:G-protein complex binds GTP IEA Mus musculus 37565 R-MMU-169904 https://reactome.org/PathwayBrowser/#/R-MMU-169904 C3G stimulates nucleotide exchange on Rap1 IEA Mus musculus 37565 R-MMU-170026 https://reactome.org/PathwayBrowser/#/R-MMU-170026 Protons are translocated from the intermembrane space to the matrix IEA Mus musculus 37565 R-MMU-170666 https://reactome.org/PathwayBrowser/#/R-MMU-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Mus musculus 37565 R-MMU-170671 https://reactome.org/PathwayBrowser/#/R-MMU-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Mus musculus 37565 R-MMU-170672 https://reactome.org/PathwayBrowser/#/R-MMU-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Mus musculus 37565 R-MMU-170676 https://reactome.org/PathwayBrowser/#/R-MMU-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Mus musculus 37565 R-MMU-170685 https://reactome.org/PathwayBrowser/#/R-MMU-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Mus musculus 37565 R-MMU-170686 https://reactome.org/PathwayBrowser/#/R-MMU-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Mus musculus 37565 R-MMU-170986 https://reactome.org/PathwayBrowser/#/R-MMU-170986 Ral-GDS binds to Ras-GTP IEA Mus musculus 37565 R-MMU-177938 https://reactome.org/PathwayBrowser/#/R-MMU-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Mus musculus 37565 R-MMU-177945 https://reactome.org/PathwayBrowser/#/R-MMU-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Mus musculus 37565 R-MMU-183002 https://reactome.org/PathwayBrowser/#/R-MMU-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Mus musculus 37565 R-MMU-183084 https://reactome.org/PathwayBrowser/#/R-MMU-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Mus musculus 37565 R-MMU-183094 https://reactome.org/PathwayBrowser/#/R-MMU-183094 CDC42:GTP binds CBL:Beta-Pix IEA Mus musculus 37565 R-MMU-186834 https://reactome.org/PathwayBrowser/#/R-MMU-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Mus musculus 37565 R-MMU-190520 https://reactome.org/PathwayBrowser/#/R-MMU-190520 Association of Golgi transport vesicles with microtubules IEA Mus musculus 37565 R-MMU-194518 https://reactome.org/PathwayBrowser/#/R-MMU-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Mus musculus 37565 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus 37565 R-MMU-2029454 https://reactome.org/PathwayBrowser/#/R-MMU-2029454 Autophosphorylation of PAK1 IEA Mus musculus 37565 R-MMU-2029456 https://reactome.org/PathwayBrowser/#/R-MMU-2029456 RAC1 and CDC42 activate PAK1 IEA Mus musculus 37565 R-MMU-2029465 https://reactome.org/PathwayBrowser/#/R-MMU-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Mus musculus 37565 R-MMU-2029466 https://reactome.org/PathwayBrowser/#/R-MMU-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Mus musculus 37565 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus 37565 R-MMU-2029469 https://reactome.org/PathwayBrowser/#/R-MMU-2029469 p-ERK phosphorylates WAVEs and ABI IEA Mus musculus 37565 R-MMU-203973 https://reactome.org/PathwayBrowser/#/R-MMU-203973 Vesicle budding IEA Mus musculus 37565 R-MMU-203977 https://reactome.org/PathwayBrowser/#/R-MMU-203977 SAR1 Activation And Membrane Binding IEA Mus musculus 37565 R-MMU-203979 https://reactome.org/PathwayBrowser/#/R-MMU-203979 Coat Assembly IEA Mus musculus 37565 R-MMU-204008 https://reactome.org/PathwayBrowser/#/R-MMU-204008 SEC31:SEC13 and v-SNARE recruitment IEA Mus musculus 37565 R-MMU-205039 https://reactome.org/PathwayBrowser/#/R-MMU-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Mus musculus 37565 R-MMU-205136 https://reactome.org/PathwayBrowser/#/R-MMU-205136 GTP-bound RAC contributes to JNK activation IEA Mus musculus 37565 R-MMU-2065539 https://reactome.org/PathwayBrowser/#/R-MMU-2065539 SREBP1A,1C,2:Importin beta-1 dissociates IEA Mus musculus 37565 R-MMU-210977 https://reactome.org/PathwayBrowser/#/R-MMU-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Mus musculus 37565 R-MMU-2130194 https://reactome.org/PathwayBrowser/#/R-MMU-2130194 ABL phosphorylates WAVEs IEA Mus musculus 37565 R-MMU-2130619 https://reactome.org/PathwayBrowser/#/R-MMU-2130619 TGN-lysosomal vesicle coat assembly IEA Mus musculus 37565 R-MMU-2130641 https://reactome.org/PathwayBrowser/#/R-MMU-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Mus musculus 37565 R-MMU-2130725 https://reactome.org/PathwayBrowser/#/R-MMU-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Mus musculus 37565 R-MMU-2130731 https://reactome.org/PathwayBrowser/#/R-MMU-2130731 Formation of COPII vesicle IEA Mus musculus 37565 R-MMU-2179407 https://reactome.org/PathwayBrowser/#/R-MMU-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Mus musculus 37565 R-MMU-2197690 https://reactome.org/PathwayBrowser/#/R-MMU-2197690 Detachment of WASP/WAVE IEA Mus musculus 37565 R-MMU-2197698 https://reactome.org/PathwayBrowser/#/R-MMU-2197698 Src phosphorylate WASP,N-WASP IEA Mus musculus 37565 R-MMU-2213243 https://reactome.org/PathwayBrowser/#/R-MMU-2213243 Fusion of COPII vesicle with Golgi complex IEA Mus musculus 37565 R-MMU-2213248 https://reactome.org/PathwayBrowser/#/R-MMU-2213248 Transport of antigen loaded MHC II molecules to surface IEA Mus musculus 37565 R-MMU-2214351 https://reactome.org/PathwayBrowser/#/R-MMU-2214351 PLK1 phosphorylates GORASP1 IEA Mus musculus 37565 R-MMU-2255341 https://reactome.org/PathwayBrowser/#/R-MMU-2255341 Rab8A/10/13/14 Exchange GDP for GTP TAS Mus musculus 37565 R-MMU-2316350 https://reactome.org/PathwayBrowser/#/R-MMU-2316350 Rab4a:GTP Activates Kif3 TAS Mus musculus 37565 R-MMU-2316351 https://reactome.org/PathwayBrowser/#/R-MMU-2316351 Translocation of Glut4 Vesicle and Docking at the Plasma Membrane TAS Mus musculus 37565 R-MMU-2316434 https://reactome.org/PathwayBrowser/#/R-MMU-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 37565 R-MMU-2408515 https://reactome.org/PathwayBrowser/#/R-MMU-2408515 Sec-tRNA(Sec) binds to Eefsec:GTP TAS Mus musculus 37565 R-MMU-2422927 https://reactome.org/PathwayBrowser/#/R-MMU-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Mus musculus 37565 R-MMU-2424476 https://reactome.org/PathwayBrowser/#/R-MMU-2424476 Activation of RAC1 by VAV2/3 IEA Mus musculus 37565 R-MMU-2424477 https://reactome.org/PathwayBrowser/#/R-MMU-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Mus musculus 37565 R-MMU-2467809 https://reactome.org/PathwayBrowser/#/R-MMU-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Mus musculus 37565 R-MMU-2467811 https://reactome.org/PathwayBrowser/#/R-MMU-2467811 Separation of sister chromatids IEA Mus musculus 37565 R-MMU-2468287 https://reactome.org/PathwayBrowser/#/R-MMU-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Mus musculus 37565 R-MMU-2484822 https://reactome.org/PathwayBrowser/#/R-MMU-2484822 Kinetochore assembly IEA Mus musculus 37565 R-MMU-2485182 https://reactome.org/PathwayBrowser/#/R-MMU-2485182 Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 IEA Mus musculus 37565 R-MMU-2562526 https://reactome.org/PathwayBrowser/#/R-MMU-2562526 PLK1 phosphorylates OPTN IEA Mus musculus 37565 R-MMU-2584246 https://reactome.org/PathwayBrowser/#/R-MMU-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Mus musculus 37565 R-MMU-2730840 https://reactome.org/PathwayBrowser/#/R-MMU-2730840 Activation of RAC1 by VAV IEA Mus musculus 37565 R-MMU-2730856 https://reactome.org/PathwayBrowser/#/R-MMU-2730856 Autophosphorylation of PAK IEA Mus musculus 37565 R-MMU-2730889 https://reactome.org/PathwayBrowser/#/R-MMU-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Mus musculus 37565 R-MMU-350769 https://reactome.org/PathwayBrowser/#/R-MMU-350769 trans-Golgi Network Coat Activation IEA Mus musculus 37565 R-MMU-354060 https://reactome.org/PathwayBrowser/#/R-MMU-354060 Translocation of RIAM to plasma membrane IEA Mus musculus 37565 R-MMU-354066 https://reactome.org/PathwayBrowser/#/R-MMU-354066 Translocation of PTK2 to Focal complexes IEA Mus musculus 37565 R-MMU-354073 https://reactome.org/PathwayBrowser/#/R-MMU-354073 Autophosphorylation of PTK2 at Y397 IEA Mus musculus 37565 R-MMU-354077 https://reactome.org/PathwayBrowser/#/R-MMU-354077 Integrin alphaIIb beta3 activation IEA Mus musculus 37565 R-MMU-354087 https://reactome.org/PathwayBrowser/#/R-MMU-354087 Recruitment of GRB2 to p-PTK2 IEA Mus musculus 37565 R-MMU-354097 https://reactome.org/PathwayBrowser/#/R-MMU-354097 Activation of Talin IEA Mus musculus 37565 R-MMU-354124 https://reactome.org/PathwayBrowser/#/R-MMU-354124 Phosphorylation of pPTK2 by SRC IEA Mus musculus 37565 R-MMU-354149 https://reactome.org/PathwayBrowser/#/R-MMU-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Mus musculus 37565 R-MMU-354165 https://reactome.org/PathwayBrowser/#/R-MMU-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Mus musculus 37565 R-MMU-354173 https://reactome.org/PathwayBrowser/#/R-MMU-354173 Activation of Rap1 by cytosolic GEFs IEA Mus musculus 37565 R-MMU-372693 https://reactome.org/PathwayBrowser/#/R-MMU-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Mus musculus 37565 R-MMU-372697 https://reactome.org/PathwayBrowser/#/R-MMU-372697 Crk binding to p130cas IEA Mus musculus 37565 R-MMU-372705 https://reactome.org/PathwayBrowser/#/R-MMU-372705 Recruitment of BCAR1 to PTK2 complex IEA Mus musculus 37565 R-MMU-372819 https://reactome.org/PathwayBrowser/#/R-MMU-372819 PCK2 phosphorylates OA to yield PEP IEA Mus musculus 37565 R-MMU-375302 https://reactome.org/PathwayBrowser/#/R-MMU-375302 Kinetochore capture of astral microtubules IEA Mus musculus 37565 R-MMU-377186 https://reactome.org/PathwayBrowser/#/R-MMU-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Mus musculus 37565 R-MMU-377640 https://reactome.org/PathwayBrowser/#/R-MMU-377640 Autophosphorylation of SRC IEA Mus musculus 37565 R-MMU-377641 https://reactome.org/PathwayBrowser/#/R-MMU-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Mus musculus 37565 R-MMU-377643 https://reactome.org/PathwayBrowser/#/R-MMU-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Mus musculus 37565 R-MMU-377644 https://reactome.org/PathwayBrowser/#/R-MMU-377644 Release of CSK from SRC IEA Mus musculus 37565 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 37565 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 37565 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 37565 R-MMU-380316 https://reactome.org/PathwayBrowser/#/R-MMU-380316 Association of NuMA with microtubules IEA Mus musculus 37565 R-MMU-380979 https://reactome.org/PathwayBrowser/#/R-MMU-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Mus musculus 37565 R-MMU-381727 https://reactome.org/PathwayBrowser/#/R-MMU-381727 RAP1A exchanges GDP for GTP IEA Mus musculus 37565 R-MMU-3858475 https://reactome.org/PathwayBrowser/#/R-MMU-3858475 ppDVL recruits RAC IEA Mus musculus 37565 R-MMU-3858495 https://reactome.org/PathwayBrowser/#/R-MMU-3858495 DAAM1 recruits GTP-bound RHOA IEA Mus musculus 37565 R-MMU-389348 https://reactome.org/PathwayBrowser/#/R-MMU-389348 Activation of Rac1 by pVav1 IEA Mus musculus 37565 R-MMU-389350 https://reactome.org/PathwayBrowser/#/R-MMU-389350 Activation of Cdc42 by pVav1 IEA Mus musculus 37565 R-MMU-389788 https://reactome.org/PathwayBrowser/#/R-MMU-389788 Activation of PAKs by RAC1 and CDC42 IEA Mus musculus 37565 R-MMU-392054 https://reactome.org/PathwayBrowser/#/R-MMU-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Mus musculus 37565 R-MMU-392064 https://reactome.org/PathwayBrowser/#/R-MMU-392064 G alpha (z) inhibits adenylate cyclase IEA Mus musculus 37565 R-MMU-392195 https://reactome.org/PathwayBrowser/#/R-MMU-392195 Gi activation by P2Y purinoceptor 12 IEA Mus musculus 37565 R-MMU-392202 https://reactome.org/PathwayBrowser/#/R-MMU-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Mus musculus 37565 R-MMU-392513 https://reactome.org/PathwayBrowser/#/R-MMU-392513 Rap1 signal termination by Rap1GAPs IEA Mus musculus 37565 R-MMU-392835 https://reactome.org/PathwayBrowser/#/R-MMU-392835 Rap1 sequesters Raf1 to inhibit ERK cascade IEA Mus musculus 37565 R-MMU-3928576 https://reactome.org/PathwayBrowser/#/R-MMU-3928576 RHOA:GTP binds ROCK, activating it IEA Mus musculus 37565 R-MMU-3928592 https://reactome.org/PathwayBrowser/#/R-MMU-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Mus musculus 37565 R-MMU-3928595 https://reactome.org/PathwayBrowser/#/R-MMU-3928595 N-WASP binds ARP2/3 and G-actin IEA Mus musculus 37565 R-MMU-3928601 https://reactome.org/PathwayBrowser/#/R-MMU-3928601 CDC42 and PIP2 bind WASL, activating it IEA Mus musculus 37565 R-MMU-3928612 https://reactome.org/PathwayBrowser/#/R-MMU-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 37565 R-MMU-3928619 https://reactome.org/PathwayBrowser/#/R-MMU-3928619 PAK1 binds RAC1:GTP IEA Mus musculus 37565 R-MMU-3928620 https://reactome.org/PathwayBrowser/#/R-MMU-3928620 PAK1 autophosphorylates IEA Mus musculus 37565 R-MMU-3928625 https://reactome.org/PathwayBrowser/#/R-MMU-3928625 PAKs autophosphorylate IEA Mus musculus 37565 R-MMU-3928628 https://reactome.org/PathwayBrowser/#/R-MMU-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 37565 R-MMU-3928633 https://reactome.org/PathwayBrowser/#/R-MMU-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Mus musculus 37565 R-MMU-3928641 https://reactome.org/PathwayBrowser/#/R-MMU-3928641 PAK binds RAC and bPIX IEA Mus musculus 37565 R-MMU-3928642 https://reactome.org/PathwayBrowser/#/R-MMU-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 37565 R-MMU-3928643 https://reactome.org/PathwayBrowser/#/R-MMU-3928643 Activation of CDC42 by intersectin-1 TAS Mus musculus 37565 R-MMU-3928647 https://reactome.org/PathwayBrowser/#/R-MMU-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Mus musculus 37565 R-MMU-3928651 https://reactome.org/PathwayBrowser/#/R-MMU-3928651 NGEF exchanges GTP for GDP on RHOA IEA Mus musculus 37565 R-MMU-392870 https://reactome.org/PathwayBrowser/#/R-MMU-392870 Gs activation by prostacyclin receptor IEA Mus musculus 37565 R-MMU-3965444 https://reactome.org/PathwayBrowser/#/R-MMU-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Mus musculus 37565 R-MMU-3965447 https://reactome.org/PathwayBrowser/#/R-MMU-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Mus musculus 37565 R-MMU-397835 https://reactome.org/PathwayBrowser/#/R-MMU-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Mus musculus 37565 R-MMU-397891 https://reactome.org/PathwayBrowser/#/R-MMU-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Mus musculus 37565 R-MMU-398184 https://reactome.org/PathwayBrowser/#/R-MMU-398184 LARG activation by G alpha 12/13 IEA Mus musculus 37565 R-MMU-398185 https://reactome.org/PathwayBrowser/#/R-MMU-398185 LARG binds plexin B1 IEA Mus musculus 37565 R-MMU-399930 https://reactome.org/PathwayBrowser/#/R-MMU-399930 Activation of PAK by Rac1 IEA Mus musculus 37565 R-MMU-399939 https://reactome.org/PathwayBrowser/#/R-MMU-399939 Autophosphorylation of PAK IEA Mus musculus 37565 R-MMU-399952 https://reactome.org/PathwayBrowser/#/R-MMU-399952 Phosphorylation of LIMK-1 by PAK IEA Mus musculus 37565 R-MMU-399998 https://reactome.org/PathwayBrowser/#/R-MMU-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Mus musculus 37565 R-MMU-400037 https://reactome.org/PathwayBrowser/#/R-MMU-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Mus musculus 37565 R-MMU-400092 https://reactome.org/PathwayBrowser/#/R-MMU-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Mus musculus 37565 R-MMU-400586 https://reactome.org/PathwayBrowser/#/R-MMU-400586 G alpha (q) binds to Trio family RhoGEFs IEA Mus musculus 37565 R-MMU-400677 https://reactome.org/PathwayBrowser/#/R-MMU-400677 Rnd1 interacts with Plexin-B1:Sema4D IEA Mus musculus 37565 R-MMU-400682 https://reactome.org/PathwayBrowser/#/R-MMU-400682 Active Rac1 interacts with Plexin-B1:Sema4D IEA Mus musculus 37565 R-MMU-4086392 https://reactome.org/PathwayBrowser/#/R-MMU-4086392 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 37565 R-MMU-4086394 https://reactome.org/PathwayBrowser/#/R-MMU-4086394 Gnat2 binds and activates Pde6 TAS Mus musculus 37565 R-MMU-4093331 https://reactome.org/PathwayBrowser/#/R-MMU-4093331 Ras:GTP binds p120-RasGAP IEA Mus musculus 37565 R-MMU-4093336 https://reactome.org/PathwayBrowser/#/R-MMU-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 37565 R-MMU-4093339 https://reactome.org/PathwayBrowser/#/R-MMU-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Mus musculus 37565 R-MMU-416358 https://reactome.org/PathwayBrowser/#/R-MMU-416358 G alpha (q) inhibits PI3K alpha IEA Mus musculus 37565 R-MMU-416516 https://reactome.org/PathwayBrowser/#/R-MMU-416516 GRK2 sequesters activated Gq IEA Mus musculus 37565 R-MMU-416530 https://reactome.org/PathwayBrowser/#/R-MMU-416530 FFAR1:FFAR1 ligands activate Gq IEA Mus musculus 37565 R-MMU-416546 https://reactome.org/PathwayBrowser/#/R-MMU-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Mus musculus 37565 R-MMU-416559 https://reactome.org/PathwayBrowser/#/R-MMU-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Mus musculus 37565 R-MMU-416562 https://reactome.org/PathwayBrowser/#/R-MMU-416562 p190RhoGAP binds Plexin-B1 IEA Mus musculus 37565 R-MMU-416588 https://reactome.org/PathwayBrowser/#/R-MMU-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Mus musculus 37565 R-MMU-418574 https://reactome.org/PathwayBrowser/#/R-MMU-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Mus musculus 37565 R-MMU-418576 https://reactome.org/PathwayBrowser/#/R-MMU-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Mus musculus 37565 R-MMU-418582 https://reactome.org/PathwayBrowser/#/R-MMU-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Mus musculus 37565 R-MMU-418850 https://reactome.org/PathwayBrowser/#/R-MMU-418850 Activation of Cdc42 IEA Mus musculus 37565 R-MMU-418856 https://reactome.org/PathwayBrowser/#/R-MMU-418856 Activation of Rac1 IEA Mus musculus 37565 R-MMU-419049 https://reactome.org/PathwayBrowser/#/R-MMU-419049 ROCK activation by RHO IEA Mus musculus 37565 R-MMU-419166 https://reactome.org/PathwayBrowser/#/R-MMU-419166 GEFs activate RhoA,B,C IEA Mus musculus 37565 R-MMU-420883 https://reactome.org/PathwayBrowser/#/R-MMU-420883 Opsins act as GEFs for G alpha-t IEA Mus musculus 37565 R-MMU-421142 https://reactome.org/PathwayBrowser/#/R-MMU-421142 Inactivation of R-Ras by Sema3A-Plexin-A1 GAP activity TAS Mus musculus 37565 R-MMU-421144 https://reactome.org/PathwayBrowser/#/R-MMU-421144 Recruitment of Rnd1 to Plexin-A TAS Mus musculus 37565 R-MMU-421147 https://reactome.org/PathwayBrowser/#/R-MMU-421147 Activation of Rac1 by FARP2 TAS Mus musculus 37565 R-MMU-421148 https://reactome.org/PathwayBrowser/#/R-MMU-421148 Rac1 binds plexin-1 TAS Mus musculus 37565 R-MMU-421831 https://reactome.org/PathwayBrowser/#/R-MMU-421831 trans-Golgi Network Coat Assembly IEA Mus musculus 37565 R-MMU-421833 https://reactome.org/PathwayBrowser/#/R-MMU-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture IEA Mus musculus 37565 R-MMU-421835 https://reactome.org/PathwayBrowser/#/R-MMU-421835 trans-Golgi Network Vesicle Scission IEA Mus musculus 37565 R-MMU-426547 https://reactome.org/PathwayBrowser/#/R-MMU-426547 Activation of Gq by Muscarinic Acetylcholine Receptor M3 TAS Mus musculus 37565 R-MMU-428750 https://reactome.org/PathwayBrowser/#/R-MMU-428750 Gq activation by TP receptor IEA Mus musculus 37565 R-MMU-428752 https://reactome.org/PathwayBrowser/#/R-MMU-428752 Dissociation of the TP:Gq complex IEA Mus musculus 37565 R-MMU-428917 https://reactome.org/PathwayBrowser/#/R-MMU-428917 G13 activation by TP receptor IEA Mus musculus 37565 R-MMU-428918 https://reactome.org/PathwayBrowser/#/R-MMU-428918 Dissociation of the TP:G13 complex IEA Mus musculus 37565 R-MMU-428941 https://reactome.org/PathwayBrowser/#/R-MMU-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Mus musculus 37565 R-MMU-429415 https://reactome.org/PathwayBrowser/#/R-MMU-429415 SYK binds to integrin alphaIIb beta3 IEA Mus musculus 37565 R-MMU-429441 https://reactome.org/PathwayBrowser/#/R-MMU-429441 SYK activation by SRC IEA Mus musculus 37565 R-MMU-432096 https://reactome.org/PathwayBrowser/#/R-MMU-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Mus musculus 37565 R-MMU-432195 https://reactome.org/PathwayBrowser/#/R-MMU-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Mus musculus 37565 R-MMU-432706 https://reactome.org/PathwayBrowser/#/R-MMU-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Mus musculus 37565 R-MMU-432707 https://reactome.org/PathwayBrowser/#/R-MMU-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Mus musculus 37565 R-MMU-432712 https://reactome.org/PathwayBrowser/#/R-MMU-432712 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane IEA Mus musculus 37565 R-MMU-442273 https://reactome.org/PathwayBrowser/#/R-MMU-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Mus musculus 37565 R-MMU-442291 https://reactome.org/PathwayBrowser/#/R-MMU-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Mus musculus 37565 R-MMU-442314 https://reactome.org/PathwayBrowser/#/R-MMU-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Mus musculus 37565 R-MMU-442572 https://reactome.org/PathwayBrowser/#/R-MMU-442572 Activation of WASP and N-WASP by CDC42 TAS Mus musculus 37565 R-MMU-443905 https://reactome.org/PathwayBrowser/#/R-MMU-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Mus musculus 37565 R-MMU-443910 https://reactome.org/PathwayBrowser/#/R-MMU-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Mus musculus 37565 R-MMU-445064 https://reactome.org/PathwayBrowser/#/R-MMU-445064 Activation of Rac1 by VAV2 IEA Mus musculus 37565 R-MMU-445071 https://reactome.org/PathwayBrowser/#/R-MMU-445071 Reinsertion of L1 into the plasma membrane IEA Mus musculus 37565 R-MMU-445072 https://reactome.org/PathwayBrowser/#/R-MMU-445072 Interaction of PAK1 with Rac1-GTP IEA Mus musculus 37565 R-MMU-445860 https://reactome.org/PathwayBrowser/#/R-MMU-445860 Activation of Phospholipase C beta1 by G(q)alpha:GTP TAS Mus musculus 37565 R-MMU-447074 https://reactome.org/PathwayBrowser/#/R-MMU-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Mus musculus 37565 R-MMU-448947 https://reactome.org/PathwayBrowser/#/R-MMU-448947 Interaction of Bnip-2 with Cdc42 TAS Mus musculus 37565 R-MMU-448958 https://reactome.org/PathwayBrowser/#/R-MMU-448958 Nuclear translocation of p38 MAPK IEA Mus musculus 37565 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 37565 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 37565 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 37565 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 37565 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 37565 R-MMU-5218804 https://reactome.org/PathwayBrowser/#/R-MMU-5218804 p38 MAPK activation by VEGFR IEA Mus musculus 37565 R-MMU-5218812 https://reactome.org/PathwayBrowser/#/R-MMU-5218812 FYN phosphorylates PAK2 IEA Mus musculus 37565 R-MMU-5218814 https://reactome.org/PathwayBrowser/#/R-MMU-5218814 PAK2 autophorylates IEA Mus musculus 37565 R-MMU-5218826 https://reactome.org/PathwayBrowser/#/R-MMU-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Mus musculus 37565 R-MMU-5218827 https://reactome.org/PathwayBrowser/#/R-MMU-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Mus musculus 37565 R-MMU-5218832 https://reactome.org/PathwayBrowser/#/R-MMU-5218832 CDC42:GTP binds PAK2 IEA Mus musculus 37565 R-MMU-5218839 https://reactome.org/PathwayBrowser/#/R-MMU-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Mus musculus 37565 R-MMU-5218841 https://reactome.org/PathwayBrowser/#/R-MMU-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Mus musculus 37565 R-MMU-5218845 https://reactome.org/PathwayBrowser/#/R-MMU-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Mus musculus 37565 R-MMU-5218850 https://reactome.org/PathwayBrowser/#/R-MMU-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 37565 R-MMU-5228992 https://reactome.org/PathwayBrowser/#/R-MMU-5228992 ROCK1,ROCK2 are activated IEA Mus musculus 37565 R-MMU-5250209 https://reactome.org/PathwayBrowser/#/R-MMU-5250209 ARL2:GTP:ARL2BP binds SLC25A4 IEA Mus musculus 37565 R-MMU-5250210 https://reactome.org/PathwayBrowser/#/R-MMU-5250210 ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix IEA Mus musculus 37565 R-MMU-5250217 https://reactome.org/PathwayBrowser/#/R-MMU-5250217 ARL2:GTP binds ARL2BP IEA Mus musculus 37565 R-MMU-5357445 https://reactome.org/PathwayBrowser/#/R-MMU-5357445 PAK1-3 dimer disassociates IEA Mus musculus 37565 R-MMU-5357472 https://reactome.org/PathwayBrowser/#/R-MMU-5357472 PAK1-3 autophosphorylates IEA Mus musculus 37565 R-MMU-5357483 https://reactome.org/PathwayBrowser/#/R-MMU-5357483 RAC1 binds PAK1-3 IEA Mus musculus 37565 R-MMU-5419261 https://reactome.org/PathwayBrowser/#/R-MMU-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Mus musculus 37565 R-MMU-5419264 https://reactome.org/PathwayBrowser/#/R-MMU-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Mus musculus 37565 R-MMU-5419271 https://reactome.org/PathwayBrowser/#/R-MMU-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Mus musculus 37565 R-MMU-5419273 https://reactome.org/PathwayBrowser/#/R-MMU-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Mus musculus 37565 R-MMU-555065 https://reactome.org/PathwayBrowser/#/R-MMU-555065 Formation of clathrin coated vesicle IEA Mus musculus 37565 R-MMU-5578744 https://reactome.org/PathwayBrowser/#/R-MMU-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Mus musculus 37565 R-MMU-5610733 https://reactome.org/PathwayBrowser/#/R-MMU-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Mus musculus 37565 R-MMU-5610767 https://reactome.org/PathwayBrowser/#/R-MMU-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Mus musculus 37565 R-MMU-5617816 https://reactome.org/PathwayBrowser/#/R-MMU-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Mus musculus 37565 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 37565 R-MMU-5618328 https://reactome.org/PathwayBrowser/#/R-MMU-5618328 ATAT acetylates microtubules IEA Mus musculus 37565 R-MMU-5618331 https://reactome.org/PathwayBrowser/#/R-MMU-5618331 HDAC6 deacetylates microtubules IEA Mus musculus 37565 R-MMU-5620914 https://reactome.org/PathwayBrowser/#/R-MMU-5620914 ARF4:GTP binds VxPx-motifs of membrane proteins IEA Mus musculus 37565 R-MMU-5620921 https://reactome.org/PathwayBrowser/#/R-MMU-5620921 ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex IEA Mus musculus 37565 R-MMU-5623508 https://reactome.org/PathwayBrowser/#/R-MMU-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Mus musculus 37565 R-MMU-5623513 https://reactome.org/PathwayBrowser/#/R-MMU-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Mus musculus 37565 R-MMU-5623519 https://reactome.org/PathwayBrowser/#/R-MMU-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Mus musculus 37565 R-MMU-5623521 https://reactome.org/PathwayBrowser/#/R-MMU-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Mus musculus 37565 R-MMU-5623524 https://reactome.org/PathwayBrowser/#/R-MMU-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Mus musculus 37565 R-MMU-5623525 https://reactome.org/PathwayBrowser/#/R-MMU-5623525 Cargo-carrying vesicles bud from the TGN IEA Mus musculus 37565 R-MMU-5623527 https://reactome.org/PathwayBrowser/#/R-MMU-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Mus musculus 37565 R-MMU-5623622 https://reactome.org/PathwayBrowser/#/R-MMU-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Mus musculus 37565 R-MMU-5623632 https://reactome.org/PathwayBrowser/#/R-MMU-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Mus musculus 37565 R-MMU-5623667 https://reactome.org/PathwayBrowser/#/R-MMU-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Mus musculus 37565 R-MMU-5624126 https://reactome.org/PathwayBrowser/#/R-MMU-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Mus musculus 37565 R-MMU-5624127 https://reactome.org/PathwayBrowser/#/R-MMU-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Mus musculus 37565 R-MMU-5624486 https://reactome.org/PathwayBrowser/#/R-MMU-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Mus musculus 37565 R-MMU-5624492 https://reactome.org/PathwayBrowser/#/R-MMU-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Mus musculus 37565 R-MMU-5624494 https://reactome.org/PathwayBrowser/#/R-MMU-5624494 RAF1 binds p21 RAS:GTP IEA Mus musculus 37565 R-MMU-5625893 https://reactome.org/PathwayBrowser/#/R-MMU-5625893 Cit binds activated Rhoa, Rhob, Rhoc and Rac1 TAS Mus musculus 37565 R-MMU-5625959 https://reactome.org/PathwayBrowser/#/R-MMU-5625959 Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) IEA Mus musculus 37565 R-MMU-5626469 https://reactome.org/PathwayBrowser/#/R-MMU-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Mus musculus 37565 R-MMU-5626507 https://reactome.org/PathwayBrowser/#/R-MMU-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Mus musculus 37565 R-MMU-5626549 https://reactome.org/PathwayBrowser/#/R-MMU-5626549 IQGAPs bind CALM1 IEA Mus musculus 37565 R-MMU-5627071 https://reactome.org/PathwayBrowser/#/R-MMU-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane IEA Mus musculus 37565 R-MMU-5627072 https://reactome.org/PathwayBrowser/#/R-MMU-5627072 RHOQ binds GOPC:CFTR IEA Mus musculus 37565 R-MMU-5627775 https://reactome.org/PathwayBrowser/#/R-MMU-5627775 Autophosphorylation of PAK1,2,3 IEA Mus musculus 37565 R-MMU-5638009 https://reactome.org/PathwayBrowser/#/R-MMU-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Mus musculus 37565 R-MMU-5638014 https://reactome.org/PathwayBrowser/#/R-MMU-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Mus musculus 37565 R-MMU-5653957 https://reactome.org/PathwayBrowser/#/R-MMU-5653957 Rag dimer formation IEA Mus musculus 37565 R-MMU-5653968 https://reactome.org/PathwayBrowser/#/R-MMU-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Mus musculus 37565 R-MMU-5653974 https://reactome.org/PathwayBrowser/#/R-MMU-5653974 Ragulator binds Rag dimers IEA Mus musculus 37565 R-MMU-5654392 https://reactome.org/PathwayBrowser/#/R-MMU-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-5654402 https://reactome.org/PathwayBrowser/#/R-MMU-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-5654413 https://reactome.org/PathwayBrowser/#/R-MMU-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-5654426 https://reactome.org/PathwayBrowser/#/R-MMU-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-5654600 https://reactome.org/PathwayBrowser/#/R-MMU-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-5654618 https://reactome.org/PathwayBrowser/#/R-MMU-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-5654647 https://reactome.org/PathwayBrowser/#/R-MMU-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-5654663 https://reactome.org/PathwayBrowser/#/R-MMU-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-5658231 https://reactome.org/PathwayBrowser/#/R-MMU-5658231 RAS GAPs stimulate RAS GTPase activity IEA Mus musculus 37565 R-MMU-5658435 https://reactome.org/PathwayBrowser/#/R-MMU-5658435 RAS GAPs bind RAS:GTP IEA Mus musculus 37565 R-MMU-5663241 https://reactome.org/PathwayBrowser/#/R-MMU-5663241 Fmnl1 binds Rac1:GTP TAS Mus musculus 37565 R-MMU-5665656 https://reactome.org/PathwayBrowser/#/R-MMU-5665656 Rac1:GTP:Fmnl1 binds Pfn1,Pfn2 TAS Mus musculus 37565 R-MMU-5665684 https://reactome.org/PathwayBrowser/#/R-MMU-5665684 Fmnl1 binds Cdc42:GTP TAS Mus musculus 37565 R-MMU-5665727 https://reactome.org/PathwayBrowser/#/R-MMU-5665727 FMNL2 binds CDC42:GTP IEA Mus musculus 37565 R-MMU-5665748 https://reactome.org/PathwayBrowser/#/R-MMU-5665748 FMNL2 binds RHOC:GTP IEA Mus musculus 37565 R-MMU-5665751 https://reactome.org/PathwayBrowser/#/R-MMU-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin IEA Mus musculus 37565 R-MMU-5665761 https://reactome.org/PathwayBrowser/#/R-MMU-5665761 FMNL3 binds RHOC:GTP IEA Mus musculus 37565 R-MMU-5665767 https://reactome.org/PathwayBrowser/#/R-MMU-5665767 Activated FMNL3 binds G-actin IEA Mus musculus 37565 R-MMU-5665802 https://reactome.org/PathwayBrowser/#/R-MMU-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Mus musculus 37565 R-MMU-5665809 https://reactome.org/PathwayBrowser/#/R-MMU-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Mus musculus 37565 R-MMU-5665982 https://reactome.org/PathwayBrowser/#/R-MMU-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 IEA Mus musculus 37565 R-MMU-5665989 https://reactome.org/PathwayBrowser/#/R-MMU-5665989 DIAPH1 binds RHOA:GTP IEA Mus musculus 37565 R-MMU-5666070 https://reactome.org/PathwayBrowser/#/R-MMU-5666070 RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes IEA Mus musculus 37565 R-MMU-5666088 https://reactome.org/PathwayBrowser/#/R-MMU-5666088 RHOD:GTP recruits DAIPH2-3 to endosomes IEA Mus musculus 37565 R-MMU-5666104 https://reactome.org/PathwayBrowser/#/R-MMU-5666104 RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes IEA Mus musculus 37565 R-MMU-5666129 https://reactome.org/PathwayBrowser/#/R-MMU-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Mus musculus 37565 R-MMU-5666160 https://reactome.org/PathwayBrowser/#/R-MMU-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Mus musculus 37565 R-MMU-5666169 https://reactome.org/PathwayBrowser/#/R-MMU-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Mus musculus 37565 R-MMU-5666183 https://reactome.org/PathwayBrowser/#/R-MMU-5666183 Rtkn binds RhoA, RhoC or RhoB TAS Mus musculus 37565 R-MMU-5666197 https://reactome.org/PathwayBrowser/#/R-MMU-5666197 RHOA:GTP:RTKN binds LIN7B IEA Mus musculus 37565 R-MMU-5666216 https://reactome.org/PathwayBrowser/#/R-MMU-5666216 RHOA:GTP:RTKN binds TAX1BP3 IEA Mus musculus 37565 R-MMU-5667008 https://reactome.org/PathwayBrowser/#/R-MMU-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Mus musculus 37565 R-MMU-5667058 https://reactome.org/PathwayBrowser/#/R-MMU-5667058 Ropn1 binds RhoA:GTP:Rhpn1 TAS Mus musculus 37565 R-MMU-5668605 https://reactome.org/PathwayBrowser/#/R-MMU-5668605 RAC2:GTP binds NOX2 complex IEA Mus musculus 37565 R-MMU-5668629 https://reactome.org/PathwayBrowser/#/R-MMU-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Mus musculus 37565 R-MMU-5668714 https://reactome.org/PathwayBrowser/#/R-MMU-5668714 RAC1:GTP binds NOX1 complex IEA Mus musculus 37565 R-MMU-5668718 https://reactome.org/PathwayBrowser/#/R-MMU-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 37565 R-MMU-5668731 https://reactome.org/PathwayBrowser/#/R-MMU-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 37565 R-MMU-5668735 https://reactome.org/PathwayBrowser/#/R-MMU-5668735 RAC1:GTP binds NOX3 complex IEA Mus musculus 37565 R-MMU-5671970 https://reactome.org/PathwayBrowser/#/R-MMU-5671970 Activated CIT binds KIF14 and PRC1 IEA Mus musculus 37565 R-MMU-5671993 https://reactome.org/PathwayBrowser/#/R-MMU-5671993 CIT-3 binds DLG4 IEA Mus musculus 37565 R-MMU-5672010 https://reactome.org/PathwayBrowser/#/R-MMU-5672010 Active MTORC1 phosphorylates ULK1 IEA Mus musculus 37565 R-MMU-5672017 https://reactome.org/PathwayBrowser/#/R-MMU-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Mus musculus 37565 R-MMU-5672027 https://reactome.org/PathwayBrowser/#/R-MMU-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Mus musculus 37565 R-MMU-5672083 https://reactome.org/PathwayBrowser/#/R-MMU-5672083 KTN1 binds Kinesin-1 IEA Mus musculus 37565 R-MMU-5672304 https://reactome.org/PathwayBrowser/#/R-MMU-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 IEA Mus musculus 37565 R-MMU-5672329 https://reactome.org/PathwayBrowser/#/R-MMU-5672329 IQGAP1 binds CLIP1 and microtubules IEA Mus musculus 37565 R-MMU-5672817 https://reactome.org/PathwayBrowser/#/R-MMU-5672817 Active MTORC1 binds the ULK1 complex IEA Mus musculus 37565 R-MMU-5672824 https://reactome.org/PathwayBrowser/#/R-MMU-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Mus musculus 37565 R-MMU-5672828 https://reactome.org/PathwayBrowser/#/R-MMU-5672828 mTORC1 phosphorylates AKT1S1 IEA Mus musculus 37565 R-MMU-5672843 https://reactome.org/PathwayBrowser/#/R-MMU-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Mus musculus 37565 R-MMU-5672950 https://reactome.org/PathwayBrowser/#/R-MMU-5672950 "Activator" RAF:YWHAB dimer binds RAS:GTP IEA Mus musculus 37565 R-MMU-5672965 https://reactome.org/PathwayBrowser/#/R-MMU-5672965 RAS GEFs promote RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-5672966 https://reactome.org/PathwayBrowser/#/R-MMU-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Mus musculus 37565 R-MMU-5672969 https://reactome.org/PathwayBrowser/#/R-MMU-5672969 Phosphorylation of RAF IEA Mus musculus 37565 R-MMU-5672972 https://reactome.org/PathwayBrowser/#/R-MMU-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Mus musculus 37565 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 37565 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 37565 R-MMU-5672980 https://reactome.org/PathwayBrowser/#/R-MMU-5672980 Dissociation of RAS:RAF complex IEA Mus musculus 37565 R-MMU-5673768 https://reactome.org/PathwayBrowser/#/R-MMU-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Mus musculus 37565 R-MMU-5674018 https://reactome.org/PathwayBrowser/#/R-MMU-5674018 BRAP binds RAS:GTP IEA Mus musculus 37565 R-MMU-5674022 https://reactome.org/PathwayBrowser/#/R-MMU-5674022 BRAP autoubiquitinates IEA Mus musculus 37565 R-MMU-5675417 https://reactome.org/PathwayBrowser/#/R-MMU-5675417 PEBP1 binds activated RAF1 IEA Mus musculus 37565 R-MMU-5675431 https://reactome.org/PathwayBrowser/#/R-MMU-5675431 PP2A dephosphorylates RAF1 IEA Mus musculus 37565 R-MMU-5675433 https://reactome.org/PathwayBrowser/#/R-MMU-5675433 PP5 dephosphorylates RAF1 S338 IEA Mus musculus 37565 R-MMU-5675790 https://reactome.org/PathwayBrowser/#/R-MMU-5675790 MTORC1 dissociates from ULK complex IEA Mus musculus 37565 R-MMU-5694409 https://reactome.org/PathwayBrowser/#/R-MMU-5694409 Nucleotide exchange on RAB1 IEA Mus musculus 37565 R-MMU-5694417 https://reactome.org/PathwayBrowser/#/R-MMU-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Mus musculus 37565 R-MMU-5694418 https://reactome.org/PathwayBrowser/#/R-MMU-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Mus musculus 37565 R-MMU-5694441 https://reactome.org/PathwayBrowser/#/R-MMU-5694441 CSNK1D phosphorylates SEC23 IEA Mus musculus 37565 R-MMU-5694522 https://reactome.org/PathwayBrowser/#/R-MMU-5694522 Inner coat assembly and cargo binding IEA Mus musculus 37565 R-MMU-5694527 https://reactome.org/PathwayBrowser/#/R-MMU-5694527 Loss of SAR1B GTPase IEA Mus musculus 37565 R-MMU-5696197 https://reactome.org/PathwayBrowser/#/R-MMU-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Mus musculus 37565 R-MMU-6785648 https://reactome.org/PathwayBrowser/#/R-MMU-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Mus musculus 37565 R-MMU-6787533 https://reactome.org/PathwayBrowser/#/R-MMU-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Mus musculus 37565 R-MMU-6788611 https://reactome.org/PathwayBrowser/#/R-MMU-6788611 HYKK phosphorylates 5HLYS IEA Mus musculus 37565 R-MMU-6789092 https://reactome.org/PathwayBrowser/#/R-MMU-6789092 NOX2 generates superoxide anion from oxygen IEA Mus musculus 37565 R-MMU-6800138 https://reactome.org/PathwayBrowser/#/R-MMU-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Mus musculus 37565 R-MMU-6807864 https://reactome.org/PathwayBrowser/#/R-MMU-6807864 RAB1:GTP recruits GBF1 to the ERGIC IEA Mus musculus 37565 R-MMU-6807866 https://reactome.org/PathwayBrowser/#/R-MMU-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Mus musculus 37565 R-MMU-6807868 https://reactome.org/PathwayBrowser/#/R-MMU-6807868 GBF1 stimulates ARF nucleotide exchange IEA Mus musculus 37565 R-MMU-6807872 https://reactome.org/PathwayBrowser/#/R-MMU-6807872 Active ARF recruits coatomer IEA Mus musculus 37565 R-MMU-6807875 https://reactome.org/PathwayBrowser/#/R-MMU-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Mus musculus 37565 R-MMU-6807877 https://reactome.org/PathwayBrowser/#/R-MMU-6807877 ARFGAPs stimulate ARF GTPase activity IEA Mus musculus 37565 R-MMU-6809003 https://reactome.org/PathwayBrowser/#/R-MMU-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Mus musculus 37565 R-MMU-6809006 https://reactome.org/PathwayBrowser/#/R-MMU-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Mus musculus 37565 R-MMU-6809010 https://reactome.org/PathwayBrowser/#/R-MMU-6809010 COPI vesicle uncoating IEA Mus musculus 37565 R-MMU-6809011 https://reactome.org/PathwayBrowser/#/R-MMU-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Mus musculus 37565 R-MMU-6811411 https://reactome.org/PathwayBrowser/#/R-MMU-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Mus musculus 37565 R-MMU-6811412 https://reactome.org/PathwayBrowser/#/R-MMU-6811412 Active ARF recruits coatomer to the Golgi IEA Mus musculus 37565 R-MMU-6811414 https://reactome.org/PathwayBrowser/#/R-MMU-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Mus musculus 37565 R-MMU-6811415 https://reactome.org/PathwayBrowser/#/R-MMU-6811415 RAB:GTP recruits GBF1 to the Golgi membrane IEA Mus musculus 37565 R-MMU-6811417 https://reactome.org/PathwayBrowser/#/R-MMU-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Mus musculus 37565 R-MMU-6811418 https://reactome.org/PathwayBrowser/#/R-MMU-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Mus musculus 37565 R-MMU-6811423 https://reactome.org/PathwayBrowser/#/R-MMU-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Mus musculus 37565 R-MMU-6811426 https://reactome.org/PathwayBrowser/#/R-MMU-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Mus musculus 37565 R-MMU-6811427 https://reactome.org/PathwayBrowser/#/R-MMU-6811427 COPI vesicle uncoating at the ER IEA Mus musculus 37565 R-MMU-6811429 https://reactome.org/PathwayBrowser/#/R-MMU-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Mus musculus 37565 R-MMU-6811431 https://reactome.org/PathwayBrowser/#/R-MMU-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Mus musculus 37565 R-MMU-6814086 https://reactome.org/PathwayBrowser/#/R-MMU-6814086 ARFRP1 recruits ARL1 to the TGN IEA Mus musculus 37565 R-MMU-6814088 https://reactome.org/PathwayBrowser/#/R-MMU-6814088 SYS1 binds AcM-ARFRP1 IEA Mus musculus 37565 R-MMU-6814091 https://reactome.org/PathwayBrowser/#/R-MMU-6814091 ARL1 recruits TGN Golgin homodimers IEA Mus musculus 37565 R-MMU-6814094 https://reactome.org/PathwayBrowser/#/R-MMU-6814094 ARL1:GTP binds ARFIP2 IEA Mus musculus 37565 R-MMU-6814096 https://reactome.org/PathwayBrowser/#/R-MMU-6814096 ARL1:GTP binds SCOC IEA Mus musculus 37565 R-MMU-6814549 https://reactome.org/PathwayBrowser/#/R-MMU-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Mus musculus 37565 R-MMU-6814559 https://reactome.org/PathwayBrowser/#/R-MMU-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Mus musculus 37565 R-MMU-6814670 https://reactome.org/PathwayBrowser/#/R-MMU-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Mus musculus 37565 R-MMU-6814671 https://reactome.org/PathwayBrowser/#/R-MMU-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Mus musculus 37565 R-MMU-6814675 https://reactome.org/PathwayBrowser/#/R-MMU-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Mus musculus 37565 R-MMU-6814682 https://reactome.org/PathwayBrowser/#/R-MMU-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Mus musculus 37565 R-MMU-6814831 https://reactome.org/PathwayBrowser/#/R-MMU-6814831 TBC1D20 binds RAB1:GTP IEA Mus musculus 37565 R-MMU-6814833 https://reactome.org/PathwayBrowser/#/R-MMU-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Mus musculus 37565 R-MMU-70241 https://reactome.org/PathwayBrowser/#/R-MMU-70241 PCK1 phosphorylates OA to yield PEP IEA Mus musculus 37565 R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Mus musculus 37565 R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Mus musculus 37565 R-MMU-71775 https://reactome.org/PathwayBrowser/#/R-MMU-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Mus musculus 37565 R-MMU-72619 https://reactome.org/PathwayBrowser/#/R-MMU-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Mus musculus 37565 R-MMU-72621 https://reactome.org/PathwayBrowser/#/R-MMU-72621 Ribosomal scanning IEA Mus musculus 37565 R-MMU-72663 https://reactome.org/PathwayBrowser/#/R-MMU-72663 De novo formation of eIF2:GTP IEA Mus musculus 37565 R-MMU-72669 https://reactome.org/PathwayBrowser/#/R-MMU-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Mus musculus 37565 R-MMU-72671 https://reactome.org/PathwayBrowser/#/R-MMU-72671 eIF5B:GTP is hydrolyzed and released IEA Mus musculus 37565 R-MMU-72672 https://reactome.org/PathwayBrowser/#/R-MMU-72672 The 60S subunit joins the translation initiation complex IEA Mus musculus 37565 R-MMU-72691 https://reactome.org/PathwayBrowser/#/R-MMU-72691 Formation of the 43S pre-initiation complex IEA Mus musculus 37565 R-MMU-72697 https://reactome.org/PathwayBrowser/#/R-MMU-72697 Start codon recognition IEA Mus musculus 37565 R-MMU-72722 https://reactome.org/PathwayBrowser/#/R-MMU-72722 eIF2 activation IEA Mus musculus 37565 R-MMU-74059 https://reactome.org/PathwayBrowser/#/R-MMU-74059 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 37565 R-MMU-74885 https://reactome.org/PathwayBrowser/#/R-MMU-74885 GUCYs converts GTP to cGMP IEA Mus musculus 37565 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 37565 R-MMU-749453 https://reactome.org/PathwayBrowser/#/R-MMU-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Mus musculus 37565 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 37565 R-MMU-751019 https://reactome.org/PathwayBrowser/#/R-MMU-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Mus musculus 37565 R-MMU-751024 https://reactome.org/PathwayBrowser/#/R-MMU-751024 The Ligand:GPCR:Gz complex dissociates IEA Mus musculus 37565 R-MMU-751029 https://reactome.org/PathwayBrowser/#/R-MMU-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Mus musculus 37565 R-MMU-77081 https://reactome.org/PathwayBrowser/#/R-MMU-77081 Formation of the CE:GMP intermediate complex IEA Mus musculus 37565 R-MMU-8847534 https://reactome.org/PathwayBrowser/#/R-MMU-8847534 RAB43 hydrolyses GTP IEA Mus musculus 37565 R-MMU-8847537 https://reactome.org/PathwayBrowser/#/R-MMU-8847537 RAB43:GTP binds USP8NL IEA Mus musculus 37565 R-MMU-8847887 https://reactome.org/PathwayBrowser/#/R-MMU-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Mus musculus 37565 R-MMU-8848618 https://reactome.org/PathwayBrowser/#/R-MMU-8848618 Activation of RAC1 by the PXN:CRK complex IEA Mus musculus 37565 R-MMU-8849082 https://reactome.org/PathwayBrowser/#/R-MMU-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Mus musculus 37565 R-MMU-8849085 https://reactome.org/PathwayBrowser/#/R-MMU-8849085 ARHGAP35 binds RHOA:GTP IEA Mus musculus 37565 R-MMU-8849348 https://reactome.org/PathwayBrowser/#/R-MMU-8849348 RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo IEA Mus musculus 37565 R-MMU-8849350 https://reactome.org/PathwayBrowser/#/R-MMU-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Mus musculus 37565 R-MMU-8849353 https://reactome.org/PathwayBrowser/#/R-MMU-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Mus musculus 37565 R-MMU-8849748 https://reactome.org/PathwayBrowser/#/R-MMU-8849748 The COG complex binds RABs at the Golgi membrane IEA Mus musculus 37565 R-MMU-8850041 https://reactome.org/PathwayBrowser/#/R-MMU-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Mus musculus 37565 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 37565 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 37565 R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 37565 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 37565 R-MMU-8851827 https://reactome.org/PathwayBrowser/#/R-MMU-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Mus musculus 37565 R-MMU-8851877 https://reactome.org/PathwayBrowser/#/R-MMU-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Mus musculus 37565 R-MMU-8851899 https://reactome.org/PathwayBrowser/#/R-MMU-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Mus musculus 37565 R-MMU-8852280 https://reactome.org/PathwayBrowser/#/R-MMU-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Mus musculus 37565 R-MMU-8852298 https://reactome.org/PathwayBrowser/#/R-MMU-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Mus musculus 37565 R-MMU-8852306 https://reactome.org/PathwayBrowser/#/R-MMU-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Mus musculus 37565 R-MMU-8854173 https://reactome.org/PathwayBrowser/#/R-MMU-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Mus musculus 37565 R-MMU-8854182 https://reactome.org/PathwayBrowser/#/R-MMU-8854182 TBC1D17 binds OPTN:RAB8A IEA Mus musculus 37565 R-MMU-8854293 https://reactome.org/PathwayBrowser/#/R-MMU-8854293 TBC1D10A (EPI64) binds ARF6:GTP IEA Mus musculus 37565 R-MMU-8854303 https://reactome.org/PathwayBrowser/#/R-MMU-8854303 TBC1D11 binds RAB6 IEA Mus musculus 37565 R-MMU-8854612 https://reactome.org/PathwayBrowser/#/R-MMU-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Mus musculus 37565 R-MMU-8856808 https://reactome.org/PathwayBrowser/#/R-MMU-8856808 Recruitment of AP-2 complex and clathrin IEA Mus musculus 37565 R-MMU-8865774 https://reactome.org/PathwayBrowser/#/R-MMU-8865774 TTLLs polyglutamylate tubulin IEA Mus musculus 37565 R-MMU-8867370 https://reactome.org/PathwayBrowser/#/R-MMU-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Mus musculus 37565 R-MMU-8868236 https://reactome.org/PathwayBrowser/#/R-MMU-8868236 BAR domain proteins recruit dynamin IEA Mus musculus 37565 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 37565 R-MMU-8868651 https://reactome.org/PathwayBrowser/#/R-MMU-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Mus musculus 37565 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 37565 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 37565 R-MMU-8875318 https://reactome.org/PathwayBrowser/#/R-MMU-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Mus musculus 37565 R-MMU-8875320 https://reactome.org/PathwayBrowser/#/R-MMU-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Mus musculus 37565 R-MMU-8875568 https://reactome.org/PathwayBrowser/#/R-MMU-8875568 RAPGEF1 activates RAP1 IEA Mus musculus 37565 R-MMU-8875591 https://reactome.org/PathwayBrowser/#/R-MMU-8875591 DOCK7 activates RAC1 IEA Mus musculus 37565 R-MMU-8875659 https://reactome.org/PathwayBrowser/#/R-MMU-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Mus musculus 37565 R-MMU-8875661 https://reactome.org/PathwayBrowser/#/R-MMU-8875661 GGA3 associates with activated MET receptor IEA Mus musculus 37565 R-MMU-8876188 https://reactome.org/PathwayBrowser/#/R-MMU-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Mus musculus 37565 R-MMU-8876190 https://reactome.org/PathwayBrowser/#/R-MMU-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Mus musculus 37565 R-MMU-8876191 https://reactome.org/PathwayBrowser/#/R-MMU-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Mus musculus 37565 R-MMU-8876193 https://reactome.org/PathwayBrowser/#/R-MMU-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Mus musculus 37565 R-MMU-8876454 https://reactome.org/PathwayBrowser/#/R-MMU-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Mus musculus 37565 R-MMU-8876615 https://reactome.org/PathwayBrowser/#/R-MMU-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Mus musculus 37565 R-MMU-8876616 https://reactome.org/PathwayBrowser/#/R-MMU-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Mus musculus 37565 R-MMU-8876837 https://reactome.org/PathwayBrowser/#/R-MMU-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Mus musculus 37565 R-MMU-8877308 https://reactome.org/PathwayBrowser/#/R-MMU-8877308 MADD exchanges GTP for GDP on RAB27 IEA Mus musculus 37565 R-MMU-8877311 https://reactome.org/PathwayBrowser/#/R-MMU-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Mus musculus 37565 R-MMU-8877451 https://reactome.org/PathwayBrowser/#/R-MMU-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Mus musculus 37565 R-MMU-8877475 https://reactome.org/PathwayBrowser/#/R-MMU-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Mus musculus 37565 R-MMU-8877612 https://reactome.org/PathwayBrowser/#/R-MMU-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Mus musculus 37565 R-MMU-8877760 https://reactome.org/PathwayBrowser/#/R-MMU-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Mus musculus 37565 R-MMU-8877813 https://reactome.org/PathwayBrowser/#/R-MMU-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Mus musculus 37565 R-MMU-8877998 https://reactome.org/PathwayBrowser/#/R-MMU-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Mus musculus 37565 R-MMU-8941613 https://reactome.org/PathwayBrowser/#/R-MMU-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-8941618 https://reactome.org/PathwayBrowser/#/R-MMU-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-8941623 https://reactome.org/PathwayBrowser/#/R-MMU-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-8941628 https://reactome.org/PathwayBrowser/#/R-MMU-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 37565 R-MMU-8944454 https://reactome.org/PathwayBrowser/#/R-MMU-8944454 mTORC1 phosphorylates MAF1 IEA Mus musculus 37565 R-MMU-8944457 https://reactome.org/PathwayBrowser/#/R-MMU-8944457 MAF1 translocates to the nucleus IEA Mus musculus 37565 R-MMU-8951490 https://reactome.org/PathwayBrowser/#/R-MMU-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Mus musculus 37565 R-MMU-8951498 https://reactome.org/PathwayBrowser/#/R-MMU-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Mus musculus 37565 R-MMU-8952716 https://reactome.org/PathwayBrowser/#/R-MMU-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Mus musculus 37565 R-MMU-8952726 https://reactome.org/PathwayBrowser/#/R-MMU-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Mus musculus 37565 R-MMU-8964229 https://reactome.org/PathwayBrowser/#/R-MMU-8964229 G alpha (i):GTP binds Src TAS Mus musculus 37565 R-MMU-8964242 https://reactome.org/PathwayBrowser/#/R-MMU-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Mus musculus 37565 R-MMU-8964246 https://reactome.org/PathwayBrowser/#/R-MMU-8964246 BTK in G alpha (12)-BTK complex is activated IEA Mus musculus 37565 R-MMU-8964274 https://reactome.org/PathwayBrowser/#/R-MMU-8964274 G alpha (12) binds BTK IEA Mus musculus 37565 R-MMU-8964280 https://reactome.org/PathwayBrowser/#/R-MMU-8964280 Active Gq binds BTK IEA Mus musculus 37565 R-MMU-8964284 https://reactome.org/PathwayBrowser/#/R-MMU-8964284 BTK in active Gq-BTK complex is activated IEA Mus musculus 37565 R-MMU-8964329 https://reactome.org/PathwayBrowser/#/R-MMU-8964329 G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC IEA Mus musculus 37565 R-MMU-8964333 https://reactome.org/PathwayBrowser/#/R-MMU-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) IEA Mus musculus 37565 R-MMU-8964340 https://reactome.org/PathwayBrowser/#/R-MMU-8964340 Gq-BTK complex dissociates to Active BTK and Gq IEA Mus musculus 37565 R-MMU-8964599 https://reactome.org/PathwayBrowser/#/R-MMU-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Mus musculus 37565 R-MMU-8964604 https://reactome.org/PathwayBrowser/#/R-MMU-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Mus musculus 37565 R-MMU-8964614 https://reactome.org/PathwayBrowser/#/R-MMU-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Mus musculus 37565 R-MMU-8980691 https://reactome.org/PathwayBrowser/#/R-MMU-8980691 RHOA GEFs activate RHOA IEA Mus musculus 37565 R-MMU-8981353 https://reactome.org/PathwayBrowser/#/R-MMU-8981353 RASA1 stimulates RAS GTPase activity IEA Mus musculus 37565 R-MMU-8981355 https://reactome.org/PathwayBrowser/#/R-MMU-8981355 RASA1 binds RAS:GTP IEA Mus musculus 37565 R-MMU-8981447 https://reactome.org/PathwayBrowser/#/R-MMU-8981447 Cit-3 binds activated Rhoa, Rhob, Rhoc and Rac1 TAS Mus musculus 37565 R-MMU-8981637 https://reactome.org/PathwayBrowser/#/R-MMU-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Mus musculus 37565 R-MMU-8981892 https://reactome.org/PathwayBrowser/#/R-MMU-8981892 Active G alpha (z) binds RGS proteins IEA Mus musculus 37565 R-MMU-8981926 https://reactome.org/PathwayBrowser/#/R-MMU-8981926 RAC1 and CDC42 activate PAK3 IEA Mus musculus 37565 R-MMU-8981931 https://reactome.org/PathwayBrowser/#/R-MMU-8981931 RAC1 and CDC42 activate PAK2 IEA Mus musculus 37565 R-MMU-8982017 https://reactome.org/PathwayBrowser/#/R-MMU-8982017 Active G alpha (q) binds RGS proteins IEA Mus musculus 37565 R-MMU-8982019 https://reactome.org/PathwayBrowser/#/R-MMU-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Mus musculus 37565 R-MMU-8982020 https://reactome.org/PathwayBrowser/#/R-MMU-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Mus musculus 37565 R-MMU-8982021 https://reactome.org/PathwayBrowser/#/R-MMU-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Mus musculus 37565 R-MMU-8982025 https://reactome.org/PathwayBrowser/#/R-MMU-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Mus musculus 37565 R-MMU-8982640 https://reactome.org/PathwayBrowser/#/R-MMU-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Mus musculus 37565 R-MMU-8985594 https://reactome.org/PathwayBrowser/#/R-MMU-8985594 MYO9B inactivates RHOA IEA Mus musculus 37565 R-MMU-9013004 https://reactome.org/PathwayBrowser/#/R-MMU-9013004 RHOA binds effectors at the ER membrane IEA Mus musculus 37565 R-MMU-9013006 https://reactome.org/PathwayBrowser/#/R-MMU-9013006 RHOA:GTP translocates to the ER membrane IEA Mus musculus 37565 R-MMU-9013009 https://reactome.org/PathwayBrowser/#/R-MMU-9013009 RHOA binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9013022 https://reactome.org/PathwayBrowser/#/R-MMU-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Mus musculus 37565 R-MMU-9013023 https://reactome.org/PathwayBrowser/#/R-MMU-9013023 RHOB GEFs activate RHOB IEA Mus musculus 37565 R-MMU-9013024 https://reactome.org/PathwayBrowser/#/R-MMU-9013024 RHOB binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9013109 https://reactome.org/PathwayBrowser/#/R-MMU-9013109 RHOC GEFs activate RHOC IEA Mus musculus 37565 R-MMU-9013110 https://reactome.org/PathwayBrowser/#/R-MMU-9013110 RHOC binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9013111 https://reactome.org/PathwayBrowser/#/R-MMU-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Mus musculus 37565 R-MMU-9013143 https://reactome.org/PathwayBrowser/#/R-MMU-9013143 RAC1 GEFs activate RAC1 IEA Mus musculus 37565 R-MMU-9013144 https://reactome.org/PathwayBrowser/#/R-MMU-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Mus musculus 37565 R-MMU-9013145 https://reactome.org/PathwayBrowser/#/R-MMU-9013145 RAC1 binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9013159 https://reactome.org/PathwayBrowser/#/R-MMU-9013159 CDC42 GEFs activate CDC42 IEA Mus musculus 37565 R-MMU-9013161 https://reactome.org/PathwayBrowser/#/R-MMU-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Mus musculus 37565 R-MMU-9013435 https://reactome.org/PathwayBrowser/#/R-MMU-9013435 RHOD auto-activates IEA Mus musculus 37565 R-MMU-9013437 https://reactome.org/PathwayBrowser/#/R-MMU-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Mus musculus 37565 R-MMU-9013438 https://reactome.org/PathwayBrowser/#/R-MMU-9013438 RHOD binds effectors at the endosome membrane IEA Mus musculus 37565 R-MMU-9013452 https://reactome.org/PathwayBrowser/#/R-MMU-9013452 RHOD:GTP translocates to the endosome membrane IEA Mus musculus 37565 R-MMU-9014294 https://reactome.org/PathwayBrowser/#/R-MMU-9014294 RAC2 binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9014295 https://reactome.org/PathwayBrowser/#/R-MMU-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Mus musculus 37565 R-MMU-9014296 https://reactome.org/PathwayBrowser/#/R-MMU-9014296 RAC2 GEFs activate RAC2 IEA Mus musculus 37565 R-MMU-9014420 https://reactome.org/PathwayBrowser/#/R-MMU-9014420 RAC2 translocates to the phagocytic vesicle membrane IEA Mus musculus 37565 R-MMU-9014424 https://reactome.org/PathwayBrowser/#/R-MMU-9014424 RAC2 binds effectors at the phagocytic vesicle membrane IEA Mus musculus 37565 R-MMU-9014433 https://reactome.org/PathwayBrowser/#/R-MMU-9014433 RHOG GEFs activate RHOG IEA Mus musculus 37565 R-MMU-9014434 https://reactome.org/PathwayBrowser/#/R-MMU-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Mus musculus 37565 R-MMU-9014449 https://reactome.org/PathwayBrowser/#/R-MMU-9014449 RHOG binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9014454 https://reactome.org/PathwayBrowser/#/R-MMU-9014454 RHOG translocates to the ER membrane IEA Mus musculus 37565 R-MMU-9014467 https://reactome.org/PathwayBrowser/#/R-MMU-9014467 RHOG binds effectors at the ER membrane IEA Mus musculus 37565 R-MMU-9017488 https://reactome.org/PathwayBrowser/#/R-MMU-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Mus musculus 37565 R-MMU-9017491 https://reactome.org/PathwayBrowser/#/R-MMU-9017491 RHOJ GEFs activate RHOJ IEA Mus musculus 37565 R-MMU-9018745 https://reactome.org/PathwayBrowser/#/R-MMU-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Mus musculus 37565 R-MMU-9018746 https://reactome.org/PathwayBrowser/#/R-MMU-9018746 RHOQ binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9018747 https://reactome.org/PathwayBrowser/#/R-MMU-9018747 RHOQ GEFs activate RHOQ IEA Mus musculus 37565 R-MMU-9018754 https://reactome.org/PathwayBrowser/#/R-MMU-9018754 GDIs bind RHOH IEA Mus musculus 37565 R-MMU-9018756 https://reactome.org/PathwayBrowser/#/R-MMU-9018756 RHOH binds GTP IEA Mus musculus 37565 R-MMU-9018758 https://reactome.org/PathwayBrowser/#/R-MMU-9018758 RHOH binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9018766 https://reactome.org/PathwayBrowser/#/R-MMU-9018766 RHOU binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9018768 https://reactome.org/PathwayBrowser/#/R-MMU-9018768 RHOU auto-activates IEA Mus musculus 37565 R-MMU-9018774 https://reactome.org/PathwayBrowser/#/R-MMU-9018774 RHOBTB1 binds GTP IEA Mus musculus 37565 R-MMU-9018778 https://reactome.org/PathwayBrowser/#/R-MMU-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Mus musculus 37565 R-MMU-9018785 https://reactome.org/PathwayBrowser/#/R-MMU-9018785 RHOBTB2 binds GTP IEA Mus musculus 37565 R-MMU-9018787 https://reactome.org/PathwayBrowser/#/R-MMU-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Mus musculus 37565 R-MMU-9018794 https://reactome.org/PathwayBrowser/#/R-MMU-9018794 RHOV binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9018798 https://reactome.org/PathwayBrowser/#/R-MMU-9018798 RHOV binds GTP IEA Mus musculus 37565 R-MMU-9018804 https://reactome.org/PathwayBrowser/#/R-MMU-9018804 RAC3 GEFs activate RAC3 IEA Mus musculus 37565 R-MMU-9018806 https://reactome.org/PathwayBrowser/#/R-MMU-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Mus musculus 37565 R-MMU-9018808 https://reactome.org/PathwayBrowser/#/R-MMU-9018808 RAC3 binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9018814 https://reactome.org/PathwayBrowser/#/R-MMU-9018814 RHOT1 hydrolyzes GTP IEA Mus musculus 37565 R-MMU-9018815 https://reactome.org/PathwayBrowser/#/R-MMU-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Mus musculus 37565 R-MMU-9018824 https://reactome.org/PathwayBrowser/#/R-MMU-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Mus musculus 37565 R-MMU-9018826 https://reactome.org/PathwayBrowser/#/R-MMU-9018826 RHOT2 hydrolyzes GTP IEA Mus musculus 37565 R-MMU-9018836 https://reactome.org/PathwayBrowser/#/R-MMU-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Mus musculus 37565 R-MMU-9029152 https://reactome.org/PathwayBrowser/#/R-MMU-9029152 Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Y-Crkl:p-Y-Shc1:Grb2-1:Sos1,p-Y-Vav1 mediates exchange of GDP for GTP bound to Ras TAS Mus musculus 37565 R-MMU-9032798 https://reactome.org/PathwayBrowser/#/R-MMU-9032798 DOCK3 activates RAC1 IEA Mus musculus 37565 R-MMU-9036301 https://reactome.org/PathwayBrowser/#/R-MMU-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Mus musculus 37565 R-MMU-939265 https://reactome.org/PathwayBrowser/#/R-MMU-939265 Activation of Rap1 by membrane-associated GEFs IEA Mus musculus 37565 R-MMU-947535 https://reactome.org/PathwayBrowser/#/R-MMU-947535 Cyclisation of GTP to precursor Z IEA Mus musculus 37565 R-MMU-9607304 https://reactome.org/PathwayBrowser/#/R-MMU-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Mus musculus 37565 R-MMU-9610152 https://reactome.org/PathwayBrowser/#/R-MMU-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Mus musculus 37565 R-MMU-9610153 https://reactome.org/PathwayBrowser/#/R-MMU-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Mus musculus 37565 R-MMU-9610154 https://reactome.org/PathwayBrowser/#/R-MMU-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Mus musculus 37565 R-MMU-9610156 https://reactome.org/PathwayBrowser/#/R-MMU-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Mus musculus 37565 R-MMU-9610163 https://reactome.org/PathwayBrowser/#/R-MMU-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Mus musculus 37565 R-MMU-9610428 https://reactome.org/PathwayBrowser/#/R-MMU-9610428 GluN1:GluN2B (Grin1:Grin2b) di-heterotetramers bind Lin7:Cask:Apba1 and Kif17 TAS Mus musculus 37565 R-MMU-9610641 https://reactome.org/PathwayBrowser/#/R-MMU-9610641 Kif17 transports GluN1:GluN2B (Grin1:Grin2b) NMDA receptors to the plasma membrane TAS Mus musculus 37565 R-MMU-9624845 https://reactome.org/PathwayBrowser/#/R-MMU-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Mus musculus 37565 R-MMU-9624876 https://reactome.org/PathwayBrowser/#/R-MMU-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Mus musculus 37565 R-MMU-9624893 https://reactome.org/PathwayBrowser/#/R-MMU-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Mus musculus 37565 R-MMU-9626848 https://reactome.org/PathwayBrowser/#/R-MMU-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Mus musculus 37565 R-MMU-9632910 https://reactome.org/PathwayBrowser/#/R-MMU-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Mus musculus 37565 R-MMU-9632918 https://reactome.org/PathwayBrowser/#/R-MMU-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Mus musculus 37565 R-MMU-9639286 https://reactome.org/PathwayBrowser/#/R-MMU-9639286 RRAGC,D exchanges GTP for GDP IEA Mus musculus 37565 R-MMU-9640167 https://reactome.org/PathwayBrowser/#/R-MMU-9640167 RRAGA,B exchanges GDP for GTP IEA Mus musculus 37565 R-MMU-9640168 https://reactome.org/PathwayBrowser/#/R-MMU-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Mus musculus 37565 R-MMU-9640195 https://reactome.org/PathwayBrowser/#/R-MMU-9640195 RRAGA,B hydrolyzes GTP IEA Mus musculus 37565 R-MMU-9645598 https://reactome.org/PathwayBrowser/#/R-MMU-9645598 RRAGC,D hydrolyzes GTP IEA Mus musculus 37565 R-MMU-9645608 https://reactome.org/PathwayBrowser/#/R-MMU-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Mus musculus 37565 R-MMU-9646393 https://reactome.org/PathwayBrowser/#/R-MMU-9646393 Hdac6 binds microtubule TAS Mus musculus 37565 R-MMU-9646468 https://reactome.org/PathwayBrowser/#/R-MMU-9646468 mTORC1 binds RHEB:GTP IEA Mus musculus 37565 R-MMU-9646679 https://reactome.org/PathwayBrowser/#/R-MMU-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Mus musculus 37565 R-MMU-9646685 https://reactome.org/PathwayBrowser/#/R-MMU-9646685 Aggresome dissociates from dynein and microtubule IEA Mus musculus 37565 R-MMU-9648017 https://reactome.org/PathwayBrowser/#/R-MMU-9648017 EML4 binds to microtubules IEA Mus musculus 37565 R-MMU-9648114 https://reactome.org/PathwayBrowser/#/R-MMU-9648114 EML4 recruits NUDC to mitotic spindle IEA Mus musculus 37565 R-MMU-9649735 https://reactome.org/PathwayBrowser/#/R-MMU-9649735 Intrinsic nucleotide exchange on RAS IEA Mus musculus 37565 R-MMU-9649736 https://reactome.org/PathwayBrowser/#/R-MMU-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Mus musculus 37565 R-MMU-9653108 https://reactome.org/PathwayBrowser/#/R-MMU-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Mus musculus 37565 R-MMU-9654523 https://reactome.org/PathwayBrowser/#/R-MMU-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Mus musculus 37565 R-MMU-9654533 https://reactome.org/PathwayBrowser/#/R-MMU-9654533 KRAS4B recycles to the plasma membrane IEA Mus musculus 37565 R-MMU-9657599 https://reactome.org/PathwayBrowser/#/R-MMU-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Mus musculus 37565 R-MMU-9657603 https://reactome.org/PathwayBrowser/#/R-MMU-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Mus musculus 37565 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 37565 R-MMU-9657608 https://reactome.org/PathwayBrowser/#/R-MMU-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Mus musculus 37565 R-MMU-9658253 https://reactome.org/PathwayBrowser/#/R-MMU-9658253 RAS:GTP binds PI3K IEA Mus musculus 37565 R-MMU-9658445 https://reactome.org/PathwayBrowser/#/R-MMU-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Mus musculus 37565 R-MMU-9660557 https://reactome.org/PathwayBrowser/#/R-MMU-9660557 RAS:GTP binds RAL GDS proteins IEA Mus musculus 37565 R-MMU-9668419 https://reactome.org/PathwayBrowser/#/R-MMU-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Mus musculus 37565 R-MMU-9682572 https://reactome.org/PathwayBrowser/#/R-MMU-9682572 Csf1r-associated Sos1 mediates exchange of GTP for GDP bound to Ras TAS Mus musculus 37565 R-MMU-9690493 https://reactome.org/PathwayBrowser/#/R-MMU-9690493 RHOB binds effectors on endosomes IEA Mus musculus 37565 R-MMU-9690494 https://reactome.org/PathwayBrowser/#/R-MMU-9690494 RHOB translocates to the endosome membrane IEA Mus musculus 37565 R-MMU-9691168 https://reactome.org/PathwayBrowser/#/R-MMU-9691168 RAC1 translocates to the endoplasmic reticulum membrane IEA Mus musculus 37565 R-MMU-9691174 https://reactome.org/PathwayBrowser/#/R-MMU-9691174 RAC1 binds effectors at the ER membrane IEA Mus musculus 37565 R-MMU-9692800 https://reactome.org/PathwayBrowser/#/R-MMU-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Mus musculus 37565 R-MMU-9692809 https://reactome.org/PathwayBrowser/#/R-MMU-9692809 CDC42 binds effectors at the ER membrane IEA Mus musculus 37565 R-MMU-9693111 https://reactome.org/PathwayBrowser/#/R-MMU-9693111 RHOF auto-activates IEA Mus musculus 37565 R-MMU-9693125 https://reactome.org/PathwayBrowser/#/R-MMU-9693125 RHOF binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9693198 https://reactome.org/PathwayBrowser/#/R-MMU-9693198 RHOD binds effectors at the plasma membrane IEA Mus musculus 37565 R-MMU-9693207 https://reactome.org/PathwayBrowser/#/R-MMU-9693207 RHOD translocates to the mitochondrial outer membrane IEA Mus musculus 37565 R-MMU-9693214 https://reactome.org/PathwayBrowser/#/R-MMU-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Mus musculus 37565 R-MMU-9693243 https://reactome.org/PathwayBrowser/#/R-MMU-9693243 RHOD translocates to the Golgi membrane IEA Mus musculus 37565 R-MMU-9693250 https://reactome.org/PathwayBrowser/#/R-MMU-9693250 RHOD binds effectors at the Golgi membrane IEA Mus musculus 37565 R-MMU-9693282 https://reactome.org/PathwayBrowser/#/R-MMU-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Mus musculus 37565 R-MMU-9696266 https://reactome.org/PathwayBrowser/#/R-MMU-9696266 RND2 binds effectors IEA Mus musculus 37565 R-MMU-9696267 https://reactome.org/PathwayBrowser/#/R-MMU-9696267 RND3 binds GTP IEA Mus musculus 37565 R-MMU-9696268 https://reactome.org/PathwayBrowser/#/R-MMU-9696268 RND3 binds effectors IEA Mus musculus 37565 R-MMU-9696271 https://reactome.org/PathwayBrowser/#/R-MMU-9696271 RND1 binds effectors IEA Mus musculus 37565 R-MMU-9696274 https://reactome.org/PathwayBrowser/#/R-MMU-9696274 RND1 binds GTP IEA Mus musculus 37565 R-MMU-9696275 https://reactome.org/PathwayBrowser/#/R-MMU-9696275 RND2 binds GTP IEA Mus musculus 37565 R-MMU-9713712 https://reactome.org/PathwayBrowser/#/R-MMU-9713712 Adcy3:Gnal:GTP converts ATP to cAMP TAS Mus musculus 37565 R-MMU-9714361 https://reactome.org/PathwayBrowser/#/R-MMU-9714361 RHOC activates endoplasmic reticulum effectors IEA Mus musculus 37565 R-MMU-9714363 https://reactome.org/PathwayBrowser/#/R-MMU-9714363 RHOC translocates to the endoplasmic reticulum membrane IEA Mus musculus 37565 R-MMU-9714477 https://reactome.org/PathwayBrowser/#/R-MMU-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Mus musculus 37565 R-MMU-9714480 https://reactome.org/PathwayBrowser/#/R-MMU-9714480 RAC2 translocates to the mitochondrial membrane IEA Mus musculus 37565 R-MMU-9714481 https://reactome.org/PathwayBrowser/#/R-MMU-9714481 RAC2 binds effectors at the ER membrane IEA Mus musculus 37565 R-MMU-9714483 https://reactome.org/PathwayBrowser/#/R-MMU-9714483 RAC2 translocates to the ER membrane IEA Mus musculus 37565 R-MMU-9714691 https://reactome.org/PathwayBrowser/#/R-MMU-9714691 RAC3 binds ER effectors IEA Mus musculus 37565 R-MMU-9714694 https://reactome.org/PathwayBrowser/#/R-MMU-9714694 RAC3 translocates to the endoplasmic reticulum membrane IEA Mus musculus 37565 R-MMU-9724864 https://reactome.org/PathwayBrowser/#/R-MMU-9724864 Gnat3 exchanges GDP for GTP in Gnat3:Gnb1:Gng13 TAS Mus musculus 37565 R-MMU-983259 https://reactome.org/PathwayBrowser/#/R-MMU-983259 Kinesins move along microtubules consuming ATP IEA Mus musculus 37565 R-MMU-983266 https://reactome.org/PathwayBrowser/#/R-MMU-983266 Kinesins bind microtubules IEA Mus musculus 37565 R-MMU-983422 https://reactome.org/PathwayBrowser/#/R-MMU-983422 Disassembly of COPII coated vesicle IEA Mus musculus 37565 R-MMU-983424 https://reactome.org/PathwayBrowser/#/R-MMU-983424 Budding of COPII coated vesicle IEA Mus musculus 37565 R-MMU-983425 https://reactome.org/PathwayBrowser/#/R-MMU-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Mus musculus 37565 R-MMU-9836404 https://reactome.org/PathwayBrowser/#/R-MMU-9836404 p-PKR dimer phosphorylates MAPT IEA Mus musculus 37565 R-MTU-936583 https://reactome.org/PathwayBrowser/#/R-MTU-936583 APS is phosphorylated to PAPS TAS Mycobacterium tuberculosis 37565 R-NUL-1250468 https://reactome.org/PathwayBrowser/#/R-NUL-1250468 Ras guanyl-nucleotide exchange mediated by Sos1 in complex with GRB2 and P-Erbb2mut TAS Homo sapiens 37565 R-NUL-1250472 https://reactome.org/PathwayBrowser/#/R-NUL-1250472 Ras guanyl-nucleotide exchange mediated by Sos1 bound to GRB2 in complex with P-Shc1:P-Erbb2mut TAS Homo sapiens 37565 R-NUL-2422970 https://reactome.org/PathwayBrowser/#/R-NUL-2422970 Phosphorylation of Gorasp1, Golga2 and RAB1A by CDK1:CCNB TAS Homo sapiens 37565 R-NUL-350365 https://reactome.org/PathwayBrowser/#/R-NUL-350365 Dvl2 binds to Rac1:GTP TAS Homo sapiens 37565 R-NUL-350485 https://reactome.org/PathwayBrowser/#/R-NUL-350485 RhoA:GTP binds to activated Daam1 TAS Homo sapiens 37565 R-NUL-391408 https://reactome.org/PathwayBrowser/#/R-NUL-391408 Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC TAS Mus musculus 37565 R-NUL-421821 https://reactome.org/PathwayBrowser/#/R-NUL-421821 G alpha (i) inhibits adenylate cyclase TAS Canis familiaris 37565 R-NUL-421961 https://reactome.org/PathwayBrowser/#/R-NUL-421961 Dissociation of beta-2 adrenergic receptor:Gs complex TAS Oryctolagus cuniculus 37565 R-NUL-428519 https://reactome.org/PathwayBrowser/#/R-NUL-428519 Inactivation of Cdc42 TAS Rattus norvegicus 37565 R-NUL-442561 https://reactome.org/PathwayBrowser/#/R-NUL-442561 WASP/N-WASP activate the Arp2/3 complex TAS Rattus norvegicus 37565 R-NUL-445082 https://reactome.org/PathwayBrowser/#/R-NUL-445082 Transport of L1 from C-domain to P-domain TAS Mus musculus 37565 R-NUL-5667039 https://reactome.org/PathwayBrowser/#/R-NUL-5667039 RHPN2 binds RHOB:GTP TAS Homo sapiens 37565 R-NUL-804924 https://reactome.org/PathwayBrowser/#/R-NUL-804924 PKC (cow) phosphorylates G alpha z (rat) TAS Bos taurus 37565 R-NUL-8867463 https://reactome.org/PathwayBrowser/#/R-NUL-8867463 Ccps deglutamylate tubulin TAS Homo sapiens 37565 R-NUL-8955728 https://reactome.org/PathwayBrowser/#/R-NUL-8955728 TTCP hydrolyzes the terminal L-Tyr residue from alpha-tubulin TAS Bos taurus 37565 R-NUL-8955873 https://reactome.org/PathwayBrowser/#/R-NUL-8955873 Polyglutamylase complex (Ttll1) polyglutamylates alpha subunits of tubulin TAS Homo sapiens 37565 R-NUL-8982704 https://reactome.org/PathwayBrowser/#/R-NUL-8982704 PKC (cow) binds G alpha z (rat) TAS Bos taurus 37565 R-NUL-9032387 https://reactome.org/PathwayBrowser/#/R-NUL-9032387 Ntrk2 activates Ras signaling through Frs2 TAS Homo sapiens 37565 R-NUL-9033341 https://reactome.org/PathwayBrowser/#/R-NUL-9033341 Ntrk2 and Cdk5 promote activation of Rac1 by Tiam1 TAS Homo sapiens 37565 R-NUL-9616174 https://reactome.org/PathwayBrowser/#/R-NUL-9616174 RAN:GTP binds transportin associated with Nup107-160 and displaces Nup107-160 TAS Homo sapiens 37565 R-NUL-9616176 https://reactome.org/PathwayBrowser/#/R-NUL-9616176 RAN:GTP binds importin beta associated with nup107-160 and displaces nup107-160 TAS Xenopus laevis 37565 R-NUL-9616949 https://reactome.org/PathwayBrowser/#/R-NUL-9616949 Ntrk3 activates Ras TAS Rattus norvegicus 37565 R-NUL-9617449 https://reactome.org/PathwayBrowser/#/R-NUL-9617449 Rasgrf1 promotes activation of HRAS TAS Rattus norvegicus 37565 R-NUL-9619539 https://reactome.org/PathwayBrowser/#/R-NUL-9619539 AMPK-negatively regulates binding of MAPT to microtubules TAS Bos taurus 37565 R-NUL-9646387 https://reactome.org/PathwayBrowser/#/R-NUL-9646387 Dynein motors transport misfolded proteins TAS Cercopithecus aethiops 37565 R-NUL-9729192 https://reactome.org/PathwayBrowser/#/R-NUL-9729192 Gnat3 exchanges GDP for GTP in Gnat3:GNB5:GNG3 TAS Bos taurus 37565 R-OCU-159534 https://reactome.org/PathwayBrowser/#/R-OCU-159534 reEF1A complexes with GTP TAS Oryctolagus cuniculus 37565 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 37565 R-OCU-159620 https://reactome.org/PathwayBrowser/#/R-OCU-159620 Aminoacyl-tRNA binds to the ribosome at the A-site TAS Oryctolagus cuniculus 37565 R-PFA-1008248 https://reactome.org/PathwayBrowser/#/R-PFA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Plasmodium falciparum 37565 R-PFA-111524 https://reactome.org/PathwayBrowser/#/R-PFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Plasmodium falciparum 37565 R-PFA-156808 https://reactome.org/PathwayBrowser/#/R-PFA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Plasmodium falciparum 37565 R-PFA-156823 https://reactome.org/PathwayBrowser/#/R-PFA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Plasmodium falciparum 37565 R-PFA-156930 https://reactome.org/PathwayBrowser/#/R-PFA-156930 GTP-binding activates eEF2 IEA Plasmodium falciparum 37565 R-PFA-157849 https://reactome.org/PathwayBrowser/#/R-PFA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Plasmodium falciparum 37565 R-PFA-203977 https://reactome.org/PathwayBrowser/#/R-PFA-203977 SAR1 Activation And Membrane Binding IEA Plasmodium falciparum 37565 R-PFA-203979 https://reactome.org/PathwayBrowser/#/R-PFA-203979 Coat Assembly IEA Plasmodium falciparum 37565 R-PFA-2214351 https://reactome.org/PathwayBrowser/#/R-PFA-2214351 PLK1 phosphorylates GORASP1 IEA Plasmodium falciparum 37565 R-PFA-350769 https://reactome.org/PathwayBrowser/#/R-PFA-350769 trans-Golgi Network Coat Activation IEA Plasmodium falciparum 37565 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 37565 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 37565 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 37565 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 37565 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 37565 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 37565 R-PFA-5618328 https://reactome.org/PathwayBrowser/#/R-PFA-5618328 ATAT acetylates microtubules IEA Plasmodium falciparum 37565 R-PFA-5618331 https://reactome.org/PathwayBrowser/#/R-PFA-5618331 HDAC6 deacetylates microtubules IEA Plasmodium falciparum 37565 R-PFA-5623508 https://reactome.org/PathwayBrowser/#/R-PFA-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Plasmodium falciparum 37565 R-PFA-5675417 https://reactome.org/PathwayBrowser/#/R-PFA-5675417 PEBP1 binds activated RAF1 IEA Plasmodium falciparum 37565 R-PFA-5675433 https://reactome.org/PathwayBrowser/#/R-PFA-5675433 PP5 dephosphorylates RAF1 S338 IEA Plasmodium falciparum 37565 R-PFA-5694409 https://reactome.org/PathwayBrowser/#/R-PFA-5694409 Nucleotide exchange on RAB1 IEA Plasmodium falciparum 37565 R-PFA-5694522 https://reactome.org/PathwayBrowser/#/R-PFA-5694522 Inner coat assembly and cargo binding IEA Plasmodium falciparum 37565 R-PFA-5694527 https://reactome.org/PathwayBrowser/#/R-PFA-5694527 Loss of SAR1B GTPase IEA Plasmodium falciparum 37565 R-PFA-5696197 https://reactome.org/PathwayBrowser/#/R-PFA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Plasmodium falciparum 37565 R-PFA-6800138 https://reactome.org/PathwayBrowser/#/R-PFA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Plasmodium falciparum 37565 R-PFA-6807868 https://reactome.org/PathwayBrowser/#/R-PFA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Plasmodium falciparum 37565 R-PFA-6807872 https://reactome.org/PathwayBrowser/#/R-PFA-6807872 Active ARF recruits coatomer IEA Plasmodium falciparum 37565 R-PFA-6811411 https://reactome.org/PathwayBrowser/#/R-PFA-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Plasmodium falciparum 37565 R-PFA-6811412 https://reactome.org/PathwayBrowser/#/R-PFA-6811412 Active ARF recruits coatomer to the Golgi IEA Plasmodium falciparum 37565 R-PFA-6811414 https://reactome.org/PathwayBrowser/#/R-PFA-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Plasmodium falciparum 37565 R-PFA-6811415 https://reactome.org/PathwayBrowser/#/R-PFA-6811415 RAB:GTP recruits GBF1 to the Golgi membrane IEA Plasmodium falciparum 37565 R-PFA-6811417 https://reactome.org/PathwayBrowser/#/R-PFA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Plasmodium falciparum 37565 R-PFA-6811418 https://reactome.org/PathwayBrowser/#/R-PFA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Plasmodium falciparum 37565 R-PFA-6814086 https://reactome.org/PathwayBrowser/#/R-PFA-6814086 ARFRP1 recruits ARL1 to the TGN IEA Plasmodium falciparum 37565 R-PFA-6814088 https://reactome.org/PathwayBrowser/#/R-PFA-6814088 SYS1 binds AcM-ARFRP1 IEA Plasmodium falciparum 37565 R-PFA-6814831 https://reactome.org/PathwayBrowser/#/R-PFA-6814831 TBC1D20 binds RAB1:GTP IEA Plasmodium falciparum 37565 R-PFA-6814833 https://reactome.org/PathwayBrowser/#/R-PFA-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Plasmodium falciparum 37565 R-PFA-71775 https://reactome.org/PathwayBrowser/#/R-PFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Plasmodium falciparum 37565 R-PFA-72621 https://reactome.org/PathwayBrowser/#/R-PFA-72621 Ribosomal scanning IEA Plasmodium falciparum 37565 R-PFA-72663 https://reactome.org/PathwayBrowser/#/R-PFA-72663 De novo formation of eIF2:GTP IEA Plasmodium falciparum 37565 R-PFA-72669 https://reactome.org/PathwayBrowser/#/R-PFA-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Plasmodium falciparum 37565 R-PFA-72671 https://reactome.org/PathwayBrowser/#/R-PFA-72671 eIF5B:GTP is hydrolyzed and released IEA Plasmodium falciparum 37565 R-PFA-72672 https://reactome.org/PathwayBrowser/#/R-PFA-72672 The 60S subunit joins the translation initiation complex IEA Plasmodium falciparum 37565 R-PFA-72691 https://reactome.org/PathwayBrowser/#/R-PFA-72691 Formation of the 43S pre-initiation complex IEA Plasmodium falciparum 37565 R-PFA-72697 https://reactome.org/PathwayBrowser/#/R-PFA-72697 Start codon recognition IEA Plasmodium falciparum 37565 R-PFA-72722 https://reactome.org/PathwayBrowser/#/R-PFA-72722 eIF2 activation IEA Plasmodium falciparum 37565 R-PFA-77081 https://reactome.org/PathwayBrowser/#/R-PFA-77081 Formation of the CE:GMP intermediate complex IEA Plasmodium falciparum 37565 R-PFA-8847534 https://reactome.org/PathwayBrowser/#/R-PFA-8847534 RAB43 hydrolyses GTP IEA Plasmodium falciparum 37565 R-PFA-8847537 https://reactome.org/PathwayBrowser/#/R-PFA-8847537 RAB43:GTP binds USP8NL IEA Plasmodium falciparum 37565 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 37565 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 37565 R-PFA-8865774 https://reactome.org/PathwayBrowser/#/R-PFA-8865774 TTLLs polyglutamylate tubulin IEA Plasmodium falciparum 37565 R-PFA-8875320 https://reactome.org/PathwayBrowser/#/R-PFA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Plasmodium falciparum 37565 R-PFA-8877451 https://reactome.org/PathwayBrowser/#/R-PFA-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Plasmodium falciparum 37565 R-PFA-8877475 https://reactome.org/PathwayBrowser/#/R-PFA-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Plasmodium falciparum 37565 R-PFA-9624845 https://reactome.org/PathwayBrowser/#/R-PFA-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Plasmodium falciparum 37565 R-PFA-9624876 https://reactome.org/PathwayBrowser/#/R-PFA-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Plasmodium falciparum 37565 R-PFA-9646685 https://reactome.org/PathwayBrowser/#/R-PFA-9646685 Aggresome dissociates from dynein and microtubule IEA Plasmodium falciparum 37565 R-PFA-9653108 https://reactome.org/PathwayBrowser/#/R-PFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Plasmodium falciparum 37565 R-RNO-1008248 https://reactome.org/PathwayBrowser/#/R-RNO-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Rattus norvegicus 37565 R-RNO-111524 https://reactome.org/PathwayBrowser/#/R-RNO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Rattus norvegicus 37565 R-RNO-111879 https://reactome.org/PathwayBrowser/#/R-RNO-111879 PIP2 hydrolysis IEA Rattus norvegicus 37565 R-RNO-112037 https://reactome.org/PathwayBrowser/#/R-RNO-112037 Inactivation of PLC beta IEA Rattus norvegicus 37565 R-RNO-112377 https://reactome.org/PathwayBrowser/#/R-RNO-112377 Grb2:Sos2:p-Y-Irs1 mediated nucleotide exchange of p21 Ras (IRS) TAS Rattus norvegicus 37565 R-RNO-112378 https://reactome.org/PathwayBrowser/#/R-RNO-112378 SOS mediated nucleotide exchange of RAS (SHC) TAS Rattus norvegicus 37565 R-RNO-114542 https://reactome.org/PathwayBrowser/#/R-RNO-114542 RAC1,RAC2,RHOG activate PI3K IEA Rattus norvegicus 37565 R-RNO-114544 https://reactome.org/PathwayBrowser/#/R-RNO-114544 p115-RhoGEF activation of RHOA IEA Rattus norvegicus 37565 R-RNO-114548 https://reactome.org/PathwayBrowser/#/R-RNO-114548 G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) IEA Rattus norvegicus 37565 R-RNO-114552 https://reactome.org/PathwayBrowser/#/R-RNO-114552 Thrombin-activated PARs activate G12/13 IEA Rattus norvegicus 37565 R-RNO-114558 https://reactome.org/PathwayBrowser/#/R-RNO-114558 Thrombin-activated PARs activate Gq IEA Rattus norvegicus 37565 R-RNO-114688 https://reactome.org/PathwayBrowser/#/R-RNO-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Rattus norvegicus 37565 R-RNO-1168636 https://reactome.org/PathwayBrowser/#/R-RNO-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Rattus norvegicus 37565 R-RNO-1250383 https://reactome.org/PathwayBrowser/#/R-RNO-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Rattus norvegicus 37565 R-RNO-1306972 https://reactome.org/PathwayBrowser/#/R-RNO-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Rattus norvegicus 37565 R-RNO-1433415 https://reactome.org/PathwayBrowser/#/R-RNO-1433415 Activation of RAC1 IEA Rattus norvegicus 37565 R-RNO-1433471 https://reactome.org/PathwayBrowser/#/R-RNO-1433471 Activation of RAS by p-KIT bound SOS1 IEA Rattus norvegicus 37565 R-RNO-1474146 https://reactome.org/PathwayBrowser/#/R-RNO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Rattus norvegicus 37565 R-RNO-156808 https://reactome.org/PathwayBrowser/#/R-RNO-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Rattus norvegicus 37565 R-RNO-156823 https://reactome.org/PathwayBrowser/#/R-RNO-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Rattus norvegicus 37565 R-RNO-156913 https://reactome.org/PathwayBrowser/#/R-RNO-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Rattus norvegicus 37565 R-RNO-156930 https://reactome.org/PathwayBrowser/#/R-RNO-156930 GTP-binding activates eEF2 IEA Rattus norvegicus 37565 R-RNO-157849 https://reactome.org/PathwayBrowser/#/R-RNO-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Rattus norvegicus 37565 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus 37565 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus 37565 R-RNO-165195 https://reactome.org/PathwayBrowser/#/R-RNO-165195 GTP loading by Rheb IEA Rattus norvegicus 37565 R-RNO-165680 https://reactome.org/PathwayBrowser/#/R-RNO-165680 Formation of active mTORC1 complex IEA Rattus norvegicus 37565 R-RNO-165692 https://reactome.org/PathwayBrowser/#/R-RNO-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Rattus norvegicus 37565 R-RNO-165718 https://reactome.org/PathwayBrowser/#/R-RNO-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Rattus norvegicus 37565 R-RNO-167415 https://reactome.org/PathwayBrowser/#/R-RNO-167415 G-protein alpha subunit is inactivated IEA Rattus norvegicus 37565 R-RNO-167429 https://reactome.org/PathwayBrowser/#/R-RNO-167429 The receptor:G-protein complex binds GTP IEA Rattus norvegicus 37565 R-RNO-169904 https://reactome.org/PathwayBrowser/#/R-RNO-169904 C3G stimulates nucleotide exchange on Rap1 IEA Rattus norvegicus 37565 R-RNO-170026 https://reactome.org/PathwayBrowser/#/R-RNO-170026 Protons are translocated from the intermembrane space to the matrix IEA Rattus norvegicus 37565 R-RNO-170666 https://reactome.org/PathwayBrowser/#/R-RNO-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Rattus norvegicus 37565 R-RNO-170671 https://reactome.org/PathwayBrowser/#/R-RNO-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Rattus norvegicus 37565 R-RNO-170672 https://reactome.org/PathwayBrowser/#/R-RNO-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Rattus norvegicus 37565 R-RNO-170676 https://reactome.org/PathwayBrowser/#/R-RNO-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Rattus norvegicus 37565 R-RNO-170685 https://reactome.org/PathwayBrowser/#/R-RNO-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Rattus norvegicus 37565 R-RNO-170686 https://reactome.org/PathwayBrowser/#/R-RNO-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Rattus norvegicus 37565 R-RNO-170986 https://reactome.org/PathwayBrowser/#/R-RNO-170986 Ral-GDS binds to Ras-GTP IEA Rattus norvegicus 37565 R-RNO-177938 https://reactome.org/PathwayBrowser/#/R-RNO-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Rattus norvegicus 37565 R-RNO-177945 https://reactome.org/PathwayBrowser/#/R-RNO-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Rattus norvegicus 37565 R-RNO-182041 https://reactome.org/PathwayBrowser/#/R-RNO-182041 Endocytosis of clathrin-coated vesicle TAS Rattus norvegicus 37565 R-RNO-182053 https://reactome.org/PathwayBrowser/#/R-RNO-182053 C3G stimulates nucleotide exchange on Rap1 TAS Rattus norvegicus 37565 R-RNO-182065 https://reactome.org/PathwayBrowser/#/R-RNO-182065 Rap1-GTP binds Raf1 TAS Rattus norvegicus 37565 R-RNO-183002 https://reactome.org/PathwayBrowser/#/R-RNO-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Rattus norvegicus 37565 R-RNO-183084 https://reactome.org/PathwayBrowser/#/R-RNO-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Rattus norvegicus 37565 R-RNO-183094 https://reactome.org/PathwayBrowser/#/R-RNO-183094 CDC42:GTP binds CBL:Beta-Pix IEA Rattus norvegicus 37565 R-RNO-186834 https://reactome.org/PathwayBrowser/#/R-RNO-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Rattus norvegicus 37565 R-RNO-187670 https://reactome.org/PathwayBrowser/#/R-RNO-187670 Activation of Src by Ral TAS Rattus norvegicus 37565 R-RNO-187759 https://reactome.org/PathwayBrowser/#/R-RNO-187759 Rit is activated TAS Rattus norvegicus 37565 R-RNO-187762 https://reactome.org/PathwayBrowser/#/R-RNO-187762 Guanine nucleotide exchange on Ral TAS Rattus norvegicus 37565 R-RNO-188339 https://reactome.org/PathwayBrowser/#/R-RNO-188339 Rit-GTP binds Raf TAS Rattus norvegicus 37565 R-RNO-190520 https://reactome.org/PathwayBrowser/#/R-RNO-190520 Association of Golgi transport vesicles with microtubules IEA Rattus norvegicus 37565 R-RNO-194518 https://reactome.org/PathwayBrowser/#/R-RNO-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Rattus norvegicus 37565 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus 37565 R-RNO-2029454 https://reactome.org/PathwayBrowser/#/R-RNO-2029454 Autophosphorylation of PAK1 IEA Rattus norvegicus 37565 R-RNO-2029456 https://reactome.org/PathwayBrowser/#/R-RNO-2029456 RAC1 and CDC42 activate PAK1 IEA Rattus norvegicus 37565 R-RNO-2029465 https://reactome.org/PathwayBrowser/#/R-RNO-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Rattus norvegicus 37565 R-RNO-2029466 https://reactome.org/PathwayBrowser/#/R-RNO-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Rattus norvegicus 37565 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus 37565 R-RNO-2029469 https://reactome.org/PathwayBrowser/#/R-RNO-2029469 p-ERK phosphorylates WAVEs and ABI IEA Rattus norvegicus 37565 R-RNO-203973 https://reactome.org/PathwayBrowser/#/R-RNO-203973 Vesicle budding IEA Rattus norvegicus 37565 R-RNO-203977 https://reactome.org/PathwayBrowser/#/R-RNO-203977 SAR1 Activation And Membrane Binding IEA Rattus norvegicus 37565 R-RNO-203979 https://reactome.org/PathwayBrowser/#/R-RNO-203979 Coat Assembly IEA Rattus norvegicus 37565 R-RNO-204008 https://reactome.org/PathwayBrowser/#/R-RNO-204008 SEC31:SEC13 and v-SNARE recruitment IEA Rattus norvegicus 37565 R-RNO-205039 https://reactome.org/PathwayBrowser/#/R-RNO-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Rattus norvegicus 37565 R-RNO-205136 https://reactome.org/PathwayBrowser/#/R-RNO-205136 GTP-bound RAC contributes to JNK activation IEA Rattus norvegicus 37565 R-RNO-2065539 https://reactome.org/PathwayBrowser/#/R-RNO-2065539 SREBP1A,1C,2:Importin beta-1 dissociates IEA Rattus norvegicus 37565 R-RNO-210977 https://reactome.org/PathwayBrowser/#/R-RNO-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Rattus norvegicus 37565 R-RNO-2130194 https://reactome.org/PathwayBrowser/#/R-RNO-2130194 ABL phosphorylates WAVEs IEA Rattus norvegicus 37565 R-RNO-2130619 https://reactome.org/PathwayBrowser/#/R-RNO-2130619 TGN-lysosomal vesicle coat assembly IEA Rattus norvegicus 37565 R-RNO-2130641 https://reactome.org/PathwayBrowser/#/R-RNO-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Rattus norvegicus 37565 R-RNO-2130725 https://reactome.org/PathwayBrowser/#/R-RNO-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Rattus norvegicus 37565 R-RNO-2130731 https://reactome.org/PathwayBrowser/#/R-RNO-2130731 Formation of COPII vesicle IEA Rattus norvegicus 37565 R-RNO-2179407 https://reactome.org/PathwayBrowser/#/R-RNO-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Rattus norvegicus 37565 R-RNO-2197690 https://reactome.org/PathwayBrowser/#/R-RNO-2197690 Detachment of WASP/WAVE IEA Rattus norvegicus 37565 R-RNO-2197698 https://reactome.org/PathwayBrowser/#/R-RNO-2197698 Src phosphorylate WASP,N-WASP IEA Rattus norvegicus 37565 R-RNO-2213243 https://reactome.org/PathwayBrowser/#/R-RNO-2213243 Fusion of COPII vesicle with Golgi complex IEA Rattus norvegicus 37565 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus 37565 R-RNO-2214351 https://reactome.org/PathwayBrowser/#/R-RNO-2214351 PLK1 phosphorylates GORASP1 IEA Rattus norvegicus 37565 R-RNO-2316434 https://reactome.org/PathwayBrowser/#/R-RNO-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 37565 R-RNO-2408535 https://reactome.org/PathwayBrowser/#/R-RNO-2408535 Sec-tRNA(Sec):Eefsec:GTP binds to Rpl30 TAS Rattus norvegicus 37565 R-RNO-2422927 https://reactome.org/PathwayBrowser/#/R-RNO-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Rattus norvegicus 37565 R-RNO-2424476 https://reactome.org/PathwayBrowser/#/R-RNO-2424476 Activation of RAC1 by VAV2/3 IEA Rattus norvegicus 37565 R-RNO-2424477 https://reactome.org/PathwayBrowser/#/R-RNO-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Rattus norvegicus 37565 R-RNO-2457808 https://reactome.org/PathwayBrowser/#/R-RNO-2457808 Rab8A/13/14 Exchange GDP for GTP TAS Rattus norvegicus 37565 R-RNO-2467809 https://reactome.org/PathwayBrowser/#/R-RNO-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Rattus norvegicus 37565 R-RNO-2467811 https://reactome.org/PathwayBrowser/#/R-RNO-2467811 Separation of sister chromatids IEA Rattus norvegicus 37565 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus 37565 R-RNO-2484822 https://reactome.org/PathwayBrowser/#/R-RNO-2484822 Kinetochore assembly IEA Rattus norvegicus 37565 R-RNO-2485182 https://reactome.org/PathwayBrowser/#/R-RNO-2485182 Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 IEA Rattus norvegicus 37565 R-RNO-2562526 https://reactome.org/PathwayBrowser/#/R-RNO-2562526 PLK1 phosphorylates OPTN IEA Rattus norvegicus 37565 R-RNO-2584246 https://reactome.org/PathwayBrowser/#/R-RNO-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Rattus norvegicus 37565 R-RNO-2730840 https://reactome.org/PathwayBrowser/#/R-RNO-2730840 Activation of RAC1 by VAV IEA Rattus norvegicus 37565 R-RNO-2730856 https://reactome.org/PathwayBrowser/#/R-RNO-2730856 Autophosphorylation of PAK IEA Rattus norvegicus 37565 R-RNO-2730889 https://reactome.org/PathwayBrowser/#/R-RNO-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Rattus norvegicus 37565 R-RNO-350769 https://reactome.org/PathwayBrowser/#/R-RNO-350769 trans-Golgi Network Coat Activation IEA Rattus norvegicus 37565 R-RNO-354060 https://reactome.org/PathwayBrowser/#/R-RNO-354060 Translocation of RIAM to plasma membrane IEA Rattus norvegicus 37565 R-RNO-354066 https://reactome.org/PathwayBrowser/#/R-RNO-354066 Translocation of PTK2 to Focal complexes IEA Rattus norvegicus 37565 R-RNO-354073 https://reactome.org/PathwayBrowser/#/R-RNO-354073 Autophosphorylation of PTK2 at Y397 IEA Rattus norvegicus 37565 R-RNO-354077 https://reactome.org/PathwayBrowser/#/R-RNO-354077 Integrin alphaIIb beta3 activation IEA Rattus norvegicus 37565 R-RNO-354087 https://reactome.org/PathwayBrowser/#/R-RNO-354087 Recruitment of GRB2 to p-PTK2 IEA Rattus norvegicus 37565 R-RNO-354097 https://reactome.org/PathwayBrowser/#/R-RNO-354097 Activation of Talin IEA Rattus norvegicus 37565 R-RNO-354124 https://reactome.org/PathwayBrowser/#/R-RNO-354124 Phosphorylation of pPTK2 by SRC IEA Rattus norvegicus 37565 R-RNO-354149 https://reactome.org/PathwayBrowser/#/R-RNO-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Rattus norvegicus 37565 R-RNO-354165 https://reactome.org/PathwayBrowser/#/R-RNO-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Rattus norvegicus 37565 R-RNO-354173 https://reactome.org/PathwayBrowser/#/R-RNO-354173 Activation of Rap1 by cytosolic GEFs IEA Rattus norvegicus 37565 R-RNO-372693 https://reactome.org/PathwayBrowser/#/R-RNO-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Rattus norvegicus 37565 R-RNO-372697 https://reactome.org/PathwayBrowser/#/R-RNO-372697 Crk binding to p130cas IEA Rattus norvegicus 37565 R-RNO-372705 https://reactome.org/PathwayBrowser/#/R-RNO-372705 Recruitment of BCAR1 to PTK2 complex IEA Rattus norvegicus 37565 R-RNO-372819 https://reactome.org/PathwayBrowser/#/R-RNO-372819 PCK2 phosphorylates OA to yield PEP IEA Rattus norvegicus 37565 R-RNO-375302 https://reactome.org/PathwayBrowser/#/R-RNO-375302 Kinetochore capture of astral microtubules IEA Rattus norvegicus 37565 R-RNO-377186 https://reactome.org/PathwayBrowser/#/R-RNO-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Rattus norvegicus 37565 R-RNO-377640 https://reactome.org/PathwayBrowser/#/R-RNO-377640 Autophosphorylation of SRC IEA Rattus norvegicus 37565 R-RNO-377641 https://reactome.org/PathwayBrowser/#/R-RNO-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Rattus norvegicus 37565 R-RNO-377643 https://reactome.org/PathwayBrowser/#/R-RNO-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Rattus norvegicus 37565 R-RNO-377644 https://reactome.org/PathwayBrowser/#/R-RNO-377644 Release of CSK from SRC IEA Rattus norvegicus 37565 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 37565 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 37565 R-RNO-380316 https://reactome.org/PathwayBrowser/#/R-RNO-380316 Association of NuMA with microtubules IEA Rattus norvegicus 37565 R-RNO-380979 https://reactome.org/PathwayBrowser/#/R-RNO-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Rattus norvegicus 37565 R-RNO-381727 https://reactome.org/PathwayBrowser/#/R-RNO-381727 RAP1A exchanges GDP for GTP IEA Rattus norvegicus 37565 R-RNO-3858475 https://reactome.org/PathwayBrowser/#/R-RNO-3858475 ppDVL recruits RAC IEA Rattus norvegicus 37565 R-RNO-3858495 https://reactome.org/PathwayBrowser/#/R-RNO-3858495 DAAM1 recruits GTP-bound RHOA IEA Rattus norvegicus 37565 R-RNO-389348 https://reactome.org/PathwayBrowser/#/R-RNO-389348 Activation of Rac1 by pVav1 IEA Rattus norvegicus 37565 R-RNO-389350 https://reactome.org/PathwayBrowser/#/R-RNO-389350 Activation of Cdc42 by pVav1 IEA Rattus norvegicus 37565 R-RNO-389788 https://reactome.org/PathwayBrowser/#/R-RNO-389788 Activation of PAKs by RAC1 and CDC42 IEA Rattus norvegicus 37565 R-RNO-392054 https://reactome.org/PathwayBrowser/#/R-RNO-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Rattus norvegicus 37565 R-RNO-392064 https://reactome.org/PathwayBrowser/#/R-RNO-392064 G alpha (z) inhibits adenylate cyclase IEA Rattus norvegicus 37565 R-RNO-392195 https://reactome.org/PathwayBrowser/#/R-RNO-392195 Gi activation by P2Y purinoceptor 12 IEA Rattus norvegicus 37565 R-RNO-392513 https://reactome.org/PathwayBrowser/#/R-RNO-392513 Rap1 signal termination by Rap1GAPs IEA Rattus norvegicus 37565 R-RNO-392835 https://reactome.org/PathwayBrowser/#/R-RNO-392835 Rap1 sequesters Raf1 to inhibit ERK cascade IEA Rattus norvegicus 37565 R-RNO-3928576 https://reactome.org/PathwayBrowser/#/R-RNO-3928576 RHOA:GTP binds ROCK, activating it IEA Rattus norvegicus 37565 R-RNO-3928592 https://reactome.org/PathwayBrowser/#/R-RNO-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Rattus norvegicus 37565 R-RNO-3928595 https://reactome.org/PathwayBrowser/#/R-RNO-3928595 N-WASP binds ARP2/3 and G-actin IEA Rattus norvegicus 37565 R-RNO-3928601 https://reactome.org/PathwayBrowser/#/R-RNO-3928601 CDC42 and PIP2 bind WASL, activating it IEA Rattus norvegicus 37565 R-RNO-3928612 https://reactome.org/PathwayBrowser/#/R-RNO-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 37565 R-RNO-3928619 https://reactome.org/PathwayBrowser/#/R-RNO-3928619 PAK1 binds RAC1:GTP IEA Rattus norvegicus 37565 R-RNO-3928620 https://reactome.org/PathwayBrowser/#/R-RNO-3928620 PAK1 autophosphorylates IEA Rattus norvegicus 37565 R-RNO-3928625 https://reactome.org/PathwayBrowser/#/R-RNO-3928625 PAKs autophosphorylate IEA Rattus norvegicus 37565 R-RNO-3928628 https://reactome.org/PathwayBrowser/#/R-RNO-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 37565 R-RNO-3928633 https://reactome.org/PathwayBrowser/#/R-RNO-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Rattus norvegicus 37565 R-RNO-3928640 https://reactome.org/PathwayBrowser/#/R-RNO-3928640 PAKs phosphorylate MLC IEA Rattus norvegicus 37565 R-RNO-3928641 https://reactome.org/PathwayBrowser/#/R-RNO-3928641 PAK binds RAC and bPIX IEA Rattus norvegicus 37565 R-RNO-3928642 https://reactome.org/PathwayBrowser/#/R-RNO-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 37565 R-RNO-3928647 https://reactome.org/PathwayBrowser/#/R-RNO-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Rattus norvegicus 37565 R-RNO-3928651 https://reactome.org/PathwayBrowser/#/R-RNO-3928651 NGEF exchanges GTP for GDP on RHOA IEA Rattus norvegicus 37565 R-RNO-3965444 https://reactome.org/PathwayBrowser/#/R-RNO-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-398184 https://reactome.org/PathwayBrowser/#/R-RNO-398184 LARG activation by G alpha 12/13 IEA Rattus norvegicus 37565 R-RNO-398185 https://reactome.org/PathwayBrowser/#/R-RNO-398185 LARG binds plexin B1 IEA Rattus norvegicus 37565 R-RNO-399930 https://reactome.org/PathwayBrowser/#/R-RNO-399930 Activation of PAK by Rac1 IEA Rattus norvegicus 37565 R-RNO-399939 https://reactome.org/PathwayBrowser/#/R-RNO-399939 Autophosphorylation of PAK IEA Rattus norvegicus 37565 R-RNO-399952 https://reactome.org/PathwayBrowser/#/R-RNO-399952 Phosphorylation of LIMK-1 by PAK IEA Rattus norvegicus 37565 R-RNO-399998 https://reactome.org/PathwayBrowser/#/R-RNO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Rattus norvegicus 37565 R-RNO-400037 https://reactome.org/PathwayBrowser/#/R-RNO-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Rattus norvegicus 37565 R-RNO-400092 https://reactome.org/PathwayBrowser/#/R-RNO-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Rattus norvegicus 37565 R-RNO-400586 https://reactome.org/PathwayBrowser/#/R-RNO-400586 G alpha (q) binds to Trio family RhoGEFs IEA Rattus norvegicus 37565 R-RNO-400677 https://reactome.org/PathwayBrowser/#/R-RNO-400677 Rnd1 interacts with Plexin-B1:Sema4D IEA Rattus norvegicus 37565 R-RNO-400682 https://reactome.org/PathwayBrowser/#/R-RNO-400682 Active Rac1 interacts with Plexin-B1:Sema4D IEA Rattus norvegicus 37565 R-RNO-4086392 https://reactome.org/PathwayBrowser/#/R-RNO-4086392 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 37565 R-RNO-4093331 https://reactome.org/PathwayBrowser/#/R-RNO-4093331 Ras:GTP binds p120-RasGAP IEA Rattus norvegicus 37565 R-RNO-4093336 https://reactome.org/PathwayBrowser/#/R-RNO-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 37565 R-RNO-4093339 https://reactome.org/PathwayBrowser/#/R-RNO-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Rattus norvegicus 37565 R-RNO-416358 https://reactome.org/PathwayBrowser/#/R-RNO-416358 G alpha (q) inhibits PI3K alpha IEA Rattus norvegicus 37565 R-RNO-416516 https://reactome.org/PathwayBrowser/#/R-RNO-416516 GRK2 sequesters activated Gq IEA Rattus norvegicus 37565 R-RNO-416530 https://reactome.org/PathwayBrowser/#/R-RNO-416530 FFAR1:FFAR1 ligands activate Gq IEA Rattus norvegicus 37565 R-RNO-416546 https://reactome.org/PathwayBrowser/#/R-RNO-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Rattus norvegicus 37565 R-RNO-416559 https://reactome.org/PathwayBrowser/#/R-RNO-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Rattus norvegicus 37565 R-RNO-416562 https://reactome.org/PathwayBrowser/#/R-RNO-416562 p190RhoGAP binds Plexin-B1 IEA Rattus norvegicus 37565 R-RNO-416588 https://reactome.org/PathwayBrowser/#/R-RNO-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Rattus norvegicus 37565 R-RNO-418574 https://reactome.org/PathwayBrowser/#/R-RNO-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Rattus norvegicus 37565 R-RNO-418582 https://reactome.org/PathwayBrowser/#/R-RNO-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Rattus norvegicus 37565 R-RNO-418850 https://reactome.org/PathwayBrowser/#/R-RNO-418850 Activation of Cdc42 IEA Rattus norvegicus 37565 R-RNO-418856 https://reactome.org/PathwayBrowser/#/R-RNO-418856 Activation of Rac1 IEA Rattus norvegicus 37565 R-RNO-419049 https://reactome.org/PathwayBrowser/#/R-RNO-419049 ROCK activation by RHO IEA Rattus norvegicus 37565 R-RNO-419166 https://reactome.org/PathwayBrowser/#/R-RNO-419166 GEFs activate RhoA,B,C IEA Rattus norvegicus 37565 R-RNO-420883 https://reactome.org/PathwayBrowser/#/R-RNO-420883 Opsins act as GEFs for G alpha-t IEA Rattus norvegicus 37565 R-RNO-421831 https://reactome.org/PathwayBrowser/#/R-RNO-421831 trans-Golgi Network Coat Assembly IEA Rattus norvegicus 37565 R-RNO-421833 https://reactome.org/PathwayBrowser/#/R-RNO-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture IEA Rattus norvegicus 37565 R-RNO-421835 https://reactome.org/PathwayBrowser/#/R-RNO-421835 trans-Golgi Network Vesicle Scission IEA Rattus norvegicus 37565 R-RNO-421896 https://reactome.org/PathwayBrowser/#/R-RNO-421896 G alpha (i)1 auto-inactivates by hydrolysing GTP to GDP TAS Rattus norvegicus 37565 R-RNO-427288 https://reactome.org/PathwayBrowser/#/R-RNO-427288 Soluble guanylate cyclase converts GTP to cGMP TAS Rattus norvegicus 37565 R-RNO-428750 https://reactome.org/PathwayBrowser/#/R-RNO-428750 Gq activation by TP receptor IEA Rattus norvegicus 37565 R-RNO-428917 https://reactome.org/PathwayBrowser/#/R-RNO-428917 G13 activation by TP receptor IEA Rattus norvegicus 37565 R-RNO-428941 https://reactome.org/PathwayBrowser/#/R-RNO-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Rattus norvegicus 37565 R-RNO-429415 https://reactome.org/PathwayBrowser/#/R-RNO-429415 SYK binds to integrin alphaIIb beta3 IEA Rattus norvegicus 37565 R-RNO-429441 https://reactome.org/PathwayBrowser/#/R-RNO-429441 SYK activation by SRC IEA Rattus norvegicus 37565 R-RNO-432096 https://reactome.org/PathwayBrowser/#/R-RNO-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Rattus norvegicus 37565 R-RNO-432195 https://reactome.org/PathwayBrowser/#/R-RNO-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Rattus norvegicus 37565 R-RNO-432706 https://reactome.org/PathwayBrowser/#/R-RNO-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Rattus norvegicus 37565 R-RNO-432707 https://reactome.org/PathwayBrowser/#/R-RNO-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Rattus norvegicus 37565 R-RNO-432712 https://reactome.org/PathwayBrowser/#/R-RNO-432712 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane IEA Rattus norvegicus 37565 R-RNO-442273 https://reactome.org/PathwayBrowser/#/R-RNO-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Rattus norvegicus 37565 R-RNO-442291 https://reactome.org/PathwayBrowser/#/R-RNO-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Rattus norvegicus 37565 R-RNO-442314 https://reactome.org/PathwayBrowser/#/R-RNO-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Rattus norvegicus 37565 R-RNO-443905 https://reactome.org/PathwayBrowser/#/R-RNO-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Rattus norvegicus 37565 R-RNO-443910 https://reactome.org/PathwayBrowser/#/R-RNO-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Rattus norvegicus 37565 R-RNO-445064 https://reactome.org/PathwayBrowser/#/R-RNO-445064 Activation of Rac1 by VAV2 IEA Rattus norvegicus 37565 R-RNO-445071 https://reactome.org/PathwayBrowser/#/R-RNO-445071 Reinsertion of L1 into the plasma membrane IEA Rattus norvegicus 37565 R-RNO-445072 https://reactome.org/PathwayBrowser/#/R-RNO-445072 Interaction of PAK1 with Rac1-GTP IEA Rattus norvegicus 37565 R-RNO-446954 https://reactome.org/PathwayBrowser/#/R-RNO-446954 Activation of G(s) by the Glucagon-like peptide-1 receptor (Glp1r, rat) TAS Rattus norvegicus 37565 R-RNO-447074 https://reactome.org/PathwayBrowser/#/R-RNO-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Rattus norvegicus 37565 R-RNO-448958 https://reactome.org/PathwayBrowser/#/R-RNO-448958 Nuclear translocation of p38 MAPK IEA Rattus norvegicus 37565 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 37565 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 37565 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 37565 R-RNO-5218804 https://reactome.org/PathwayBrowser/#/R-RNO-5218804 p38 MAPK activation by VEGFR IEA Rattus norvegicus 37565 R-RNO-5218812 https://reactome.org/PathwayBrowser/#/R-RNO-5218812 FYN phosphorylates PAK2 IEA Rattus norvegicus 37565 R-RNO-5218814 https://reactome.org/PathwayBrowser/#/R-RNO-5218814 PAK2 autophorylates IEA Rattus norvegicus 37565 R-RNO-5218826 https://reactome.org/PathwayBrowser/#/R-RNO-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Rattus norvegicus 37565 R-RNO-5218827 https://reactome.org/PathwayBrowser/#/R-RNO-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Rattus norvegicus 37565 R-RNO-5218832 https://reactome.org/PathwayBrowser/#/R-RNO-5218832 CDC42:GTP binds PAK2 IEA Rattus norvegicus 37565 R-RNO-5218839 https://reactome.org/PathwayBrowser/#/R-RNO-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Rattus norvegicus 37565 R-RNO-5218841 https://reactome.org/PathwayBrowser/#/R-RNO-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Rattus norvegicus 37565 R-RNO-5218845 https://reactome.org/PathwayBrowser/#/R-RNO-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Rattus norvegicus 37565 R-RNO-5218850 https://reactome.org/PathwayBrowser/#/R-RNO-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 37565 R-RNO-5228992 https://reactome.org/PathwayBrowser/#/R-RNO-5228992 ROCK1,ROCK2 are activated IEA Rattus norvegicus 37565 R-RNO-5250209 https://reactome.org/PathwayBrowser/#/R-RNO-5250209 ARL2:GTP:ARL2BP binds SLC25A4 IEA Rattus norvegicus 37565 R-RNO-5250210 https://reactome.org/PathwayBrowser/#/R-RNO-5250210 ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix IEA Rattus norvegicus 37565 R-RNO-5250217 https://reactome.org/PathwayBrowser/#/R-RNO-5250217 ARL2:GTP binds ARL2BP IEA Rattus norvegicus 37565 R-RNO-5333610 https://reactome.org/PathwayBrowser/#/R-RNO-5333610 Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec-tRNA(Sec):Eefsec:GTP is hydrolysed to Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec and Eefsec:GDP by Eefsec TAS Rattus norvegicus 37565 R-RNO-5357445 https://reactome.org/PathwayBrowser/#/R-RNO-5357445 PAK1-3 dimer disassociates IEA Rattus norvegicus 37565 R-RNO-5357472 https://reactome.org/PathwayBrowser/#/R-RNO-5357472 PAK1-3 autophosphorylates IEA Rattus norvegicus 37565 R-RNO-5357483 https://reactome.org/PathwayBrowser/#/R-RNO-5357483 RAC1 binds PAK1-3 IEA Rattus norvegicus 37565 R-RNO-5419261 https://reactome.org/PathwayBrowser/#/R-RNO-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Rattus norvegicus 37565 R-RNO-5419264 https://reactome.org/PathwayBrowser/#/R-RNO-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Rattus norvegicus 37565 R-RNO-5419271 https://reactome.org/PathwayBrowser/#/R-RNO-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Rattus norvegicus 37565 R-RNO-5419273 https://reactome.org/PathwayBrowser/#/R-RNO-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Rattus norvegicus 37565 R-RNO-555065 https://reactome.org/PathwayBrowser/#/R-RNO-555065 Formation of clathrin coated vesicle IEA Rattus norvegicus 37565 R-RNO-5578744 https://reactome.org/PathwayBrowser/#/R-RNO-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Rattus norvegicus 37565 R-RNO-5610733 https://reactome.org/PathwayBrowser/#/R-RNO-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Rattus norvegicus 37565 R-RNO-5610767 https://reactome.org/PathwayBrowser/#/R-RNO-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Rattus norvegicus 37565 R-RNO-5617816 https://reactome.org/PathwayBrowser/#/R-RNO-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus 37565 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 37565 R-RNO-5618328 https://reactome.org/PathwayBrowser/#/R-RNO-5618328 ATAT acetylates microtubules IEA Rattus norvegicus 37565 R-RNO-5620914 https://reactome.org/PathwayBrowser/#/R-RNO-5620914 ARF4:GTP binds VxPx-motifs of membrane proteins IEA Rattus norvegicus 37565 R-RNO-5623508 https://reactome.org/PathwayBrowser/#/R-RNO-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Rattus norvegicus 37565 R-RNO-5623513 https://reactome.org/PathwayBrowser/#/R-RNO-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Rattus norvegicus 37565 R-RNO-5623519 https://reactome.org/PathwayBrowser/#/R-RNO-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Rattus norvegicus 37565 R-RNO-5623521 https://reactome.org/PathwayBrowser/#/R-RNO-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus 37565 R-RNO-5623524 https://reactome.org/PathwayBrowser/#/R-RNO-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Rattus norvegicus 37565 R-RNO-5623525 https://reactome.org/PathwayBrowser/#/R-RNO-5623525 Cargo-carrying vesicles bud from the TGN IEA Rattus norvegicus 37565 R-RNO-5623527 https://reactome.org/PathwayBrowser/#/R-RNO-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Rattus norvegicus 37565 R-RNO-5623622 https://reactome.org/PathwayBrowser/#/R-RNO-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Rattus norvegicus 37565 R-RNO-5623632 https://reactome.org/PathwayBrowser/#/R-RNO-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Rattus norvegicus 37565 R-RNO-5623667 https://reactome.org/PathwayBrowser/#/R-RNO-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Rattus norvegicus 37565 R-RNO-5624126 https://reactome.org/PathwayBrowser/#/R-RNO-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Rattus norvegicus 37565 R-RNO-5624127 https://reactome.org/PathwayBrowser/#/R-RNO-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Rattus norvegicus 37565 R-RNO-5624486 https://reactome.org/PathwayBrowser/#/R-RNO-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Rattus norvegicus 37565 R-RNO-5624492 https://reactome.org/PathwayBrowser/#/R-RNO-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Rattus norvegicus 37565 R-RNO-5624494 https://reactome.org/PathwayBrowser/#/R-RNO-5624494 RAF1 binds p21 RAS:GTP IEA Rattus norvegicus 37565 R-RNO-5625959 https://reactome.org/PathwayBrowser/#/R-RNO-5625959 Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) IEA Rattus norvegicus 37565 R-RNO-5626469 https://reactome.org/PathwayBrowser/#/R-RNO-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Rattus norvegicus 37565 R-RNO-5626507 https://reactome.org/PathwayBrowser/#/R-RNO-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Rattus norvegicus 37565 R-RNO-5626549 https://reactome.org/PathwayBrowser/#/R-RNO-5626549 IQGAPs bind CALM1 IEA Rattus norvegicus 37565 R-RNO-5627071 https://reactome.org/PathwayBrowser/#/R-RNO-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane IEA Rattus norvegicus 37565 R-RNO-5627072 https://reactome.org/PathwayBrowser/#/R-RNO-5627072 RHOQ binds GOPC:CFTR IEA Rattus norvegicus 37565 R-RNO-5627775 https://reactome.org/PathwayBrowser/#/R-RNO-5627775 Autophosphorylation of PAK1,2,3 IEA Rattus norvegicus 37565 R-RNO-5638009 https://reactome.org/PathwayBrowser/#/R-RNO-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Rattus norvegicus 37565 R-RNO-5638014 https://reactome.org/PathwayBrowser/#/R-RNO-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Rattus norvegicus 37565 R-RNO-5653957 https://reactome.org/PathwayBrowser/#/R-RNO-5653957 Rag dimer formation IEA Rattus norvegicus 37565 R-RNO-5653968 https://reactome.org/PathwayBrowser/#/R-RNO-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Rattus norvegicus 37565 R-RNO-5653974 https://reactome.org/PathwayBrowser/#/R-RNO-5653974 Ragulator binds Rag dimers IEA Rattus norvegicus 37565 R-RNO-5654392 https://reactome.org/PathwayBrowser/#/R-RNO-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-5654402 https://reactome.org/PathwayBrowser/#/R-RNO-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-5654413 https://reactome.org/PathwayBrowser/#/R-RNO-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-5654426 https://reactome.org/PathwayBrowser/#/R-RNO-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-5654600 https://reactome.org/PathwayBrowser/#/R-RNO-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-5654618 https://reactome.org/PathwayBrowser/#/R-RNO-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-5654647 https://reactome.org/PathwayBrowser/#/R-RNO-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-5654663 https://reactome.org/PathwayBrowser/#/R-RNO-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-5658231 https://reactome.org/PathwayBrowser/#/R-RNO-5658231 RAS GAPs stimulate RAS GTPase activity IEA Rattus norvegicus 37565 R-RNO-5658435 https://reactome.org/PathwayBrowser/#/R-RNO-5658435 RAS GAPs bind RAS:GTP IEA Rattus norvegicus 37565 R-RNO-5665727 https://reactome.org/PathwayBrowser/#/R-RNO-5665727 FMNL2 binds CDC42:GTP IEA Rattus norvegicus 37565 R-RNO-5665751 https://reactome.org/PathwayBrowser/#/R-RNO-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin IEA Rattus norvegicus 37565 R-RNO-5665802 https://reactome.org/PathwayBrowser/#/R-RNO-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Rattus norvegicus 37565 R-RNO-5665809 https://reactome.org/PathwayBrowser/#/R-RNO-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Rattus norvegicus 37565 R-RNO-5665982 https://reactome.org/PathwayBrowser/#/R-RNO-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 IEA Rattus norvegicus 37565 R-RNO-5665989 https://reactome.org/PathwayBrowser/#/R-RNO-5665989 DIAPH1 binds RHOA:GTP IEA Rattus norvegicus 37565 R-RNO-5666070 https://reactome.org/PathwayBrowser/#/R-RNO-5666070 RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes IEA Rattus norvegicus 37565 R-RNO-5666088 https://reactome.org/PathwayBrowser/#/R-RNO-5666088 RHOD:GTP recruits DAIPH2-3 to endosomes IEA Rattus norvegicus 37565 R-RNO-5666104 https://reactome.org/PathwayBrowser/#/R-RNO-5666104 RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes IEA Rattus norvegicus 37565 R-RNO-5666129 https://reactome.org/PathwayBrowser/#/R-RNO-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Rattus norvegicus 37565 R-RNO-5666160 https://reactome.org/PathwayBrowser/#/R-RNO-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Rattus norvegicus 37565 R-RNO-5666169 https://reactome.org/PathwayBrowser/#/R-RNO-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Rattus norvegicus 37565 R-RNO-5666197 https://reactome.org/PathwayBrowser/#/R-RNO-5666197 RHOA:GTP:RTKN binds LIN7B IEA Rattus norvegicus 37565 R-RNO-5666216 https://reactome.org/PathwayBrowser/#/R-RNO-5666216 RHOA:GTP:RTKN binds TAX1BP3 IEA Rattus norvegicus 37565 R-RNO-5667008 https://reactome.org/PathwayBrowser/#/R-RNO-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Rattus norvegicus 37565 R-RNO-5668605 https://reactome.org/PathwayBrowser/#/R-RNO-5668605 RAC2:GTP binds NOX2 complex IEA Rattus norvegicus 37565 R-RNO-5668629 https://reactome.org/PathwayBrowser/#/R-RNO-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Rattus norvegicus 37565 R-RNO-5668714 https://reactome.org/PathwayBrowser/#/R-RNO-5668714 RAC1:GTP binds NOX1 complex IEA Rattus norvegicus 37565 R-RNO-5668718 https://reactome.org/PathwayBrowser/#/R-RNO-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 37565 R-RNO-5668731 https://reactome.org/PathwayBrowser/#/R-RNO-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 37565 R-RNO-5668735 https://reactome.org/PathwayBrowser/#/R-RNO-5668735 RAC1:GTP binds NOX3 complex IEA Rattus norvegicus 37565 R-RNO-5671970 https://reactome.org/PathwayBrowser/#/R-RNO-5671970 Activated CIT binds KIF14 and PRC1 IEA Rattus norvegicus 37565 R-RNO-5671993 https://reactome.org/PathwayBrowser/#/R-RNO-5671993 CIT-3 binds DLG4 IEA Rattus norvegicus 37565 R-RNO-5672010 https://reactome.org/PathwayBrowser/#/R-RNO-5672010 Active MTORC1 phosphorylates ULK1 IEA Rattus norvegicus 37565 R-RNO-5672017 https://reactome.org/PathwayBrowser/#/R-RNO-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Rattus norvegicus 37565 R-RNO-5672027 https://reactome.org/PathwayBrowser/#/R-RNO-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Rattus norvegicus 37565 R-RNO-5672083 https://reactome.org/PathwayBrowser/#/R-RNO-5672083 KTN1 binds Kinesin-1 IEA Rattus norvegicus 37565 R-RNO-5672329 https://reactome.org/PathwayBrowser/#/R-RNO-5672329 IQGAP1 binds CLIP1 and microtubules IEA Rattus norvegicus 37565 R-RNO-5672817 https://reactome.org/PathwayBrowser/#/R-RNO-5672817 Active MTORC1 binds the ULK1 complex IEA Rattus norvegicus 37565 R-RNO-5672824 https://reactome.org/PathwayBrowser/#/R-RNO-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Rattus norvegicus 37565 R-RNO-5672828 https://reactome.org/PathwayBrowser/#/R-RNO-5672828 mTORC1 phosphorylates AKT1S1 IEA Rattus norvegicus 37565 R-RNO-5672843 https://reactome.org/PathwayBrowser/#/R-RNO-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Rattus norvegicus 37565 R-RNO-5672950 https://reactome.org/PathwayBrowser/#/R-RNO-5672950 "Activator" RAF:YWHAB dimer binds RAS:GTP IEA Rattus norvegicus 37565 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-5672966 https://reactome.org/PathwayBrowser/#/R-RNO-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Rattus norvegicus 37565 R-RNO-5672969 https://reactome.org/PathwayBrowser/#/R-RNO-5672969 Phosphorylation of RAF IEA Rattus norvegicus 37565 R-RNO-5672972 https://reactome.org/PathwayBrowser/#/R-RNO-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Rattus norvegicus 37565 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 37565 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 37565 R-RNO-5672980 https://reactome.org/PathwayBrowser/#/R-RNO-5672980 Dissociation of RAS:RAF complex IEA Rattus norvegicus 37565 R-RNO-5673768 https://reactome.org/PathwayBrowser/#/R-RNO-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Rattus norvegicus 37565 R-RNO-5674018 https://reactome.org/PathwayBrowser/#/R-RNO-5674018 BRAP binds RAS:GTP IEA Rattus norvegicus 37565 R-RNO-5674022 https://reactome.org/PathwayBrowser/#/R-RNO-5674022 BRAP autoubiquitinates IEA Rattus norvegicus 37565 R-RNO-5675417 https://reactome.org/PathwayBrowser/#/R-RNO-5675417 PEBP1 binds activated RAF1 IEA Rattus norvegicus 37565 R-RNO-5675431 https://reactome.org/PathwayBrowser/#/R-RNO-5675431 PP2A dephosphorylates RAF1 IEA Rattus norvegicus 37565 R-RNO-5675433 https://reactome.org/PathwayBrowser/#/R-RNO-5675433 PP5 dephosphorylates RAF1 S338 IEA Rattus norvegicus 37565 R-RNO-5675790 https://reactome.org/PathwayBrowser/#/R-RNO-5675790 MTORC1 dissociates from ULK complex IEA Rattus norvegicus 37565 R-RNO-5694409 https://reactome.org/PathwayBrowser/#/R-RNO-5694409 Nucleotide exchange on RAB1 IEA Rattus norvegicus 37565 R-RNO-5694417 https://reactome.org/PathwayBrowser/#/R-RNO-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Rattus norvegicus 37565 R-RNO-5694418 https://reactome.org/PathwayBrowser/#/R-RNO-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Rattus norvegicus 37565 R-RNO-5694441 https://reactome.org/PathwayBrowser/#/R-RNO-5694441 CSNK1D phosphorylates SEC23 IEA Rattus norvegicus 37565 R-RNO-5694522 https://reactome.org/PathwayBrowser/#/R-RNO-5694522 Inner coat assembly and cargo binding IEA Rattus norvegicus 37565 R-RNO-5694527 https://reactome.org/PathwayBrowser/#/R-RNO-5694527 Loss of SAR1B GTPase IEA Rattus norvegicus 37565 R-RNO-5696197 https://reactome.org/PathwayBrowser/#/R-RNO-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Rattus norvegicus 37565 R-RNO-6785648 https://reactome.org/PathwayBrowser/#/R-RNO-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Rattus norvegicus 37565 R-RNO-6787533 https://reactome.org/PathwayBrowser/#/R-RNO-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Rattus norvegicus 37565 R-RNO-6788611 https://reactome.org/PathwayBrowser/#/R-RNO-6788611 HYKK phosphorylates 5HLYS IEA Rattus norvegicus 37565 R-RNO-6789092 https://reactome.org/PathwayBrowser/#/R-RNO-6789092 NOX2 generates superoxide anion from oxygen IEA Rattus norvegicus 37565 R-RNO-6807864 https://reactome.org/PathwayBrowser/#/R-RNO-6807864 RAB1:GTP recruits GBF1 to the ERGIC IEA Rattus norvegicus 37565 R-RNO-6807866 https://reactome.org/PathwayBrowser/#/R-RNO-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Rattus norvegicus 37565 R-RNO-6807868 https://reactome.org/PathwayBrowser/#/R-RNO-6807868 GBF1 stimulates ARF nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-6807872 https://reactome.org/PathwayBrowser/#/R-RNO-6807872 Active ARF recruits coatomer IEA Rattus norvegicus 37565 R-RNO-6807875 https://reactome.org/PathwayBrowser/#/R-RNO-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Rattus norvegicus 37565 R-RNO-6807877 https://reactome.org/PathwayBrowser/#/R-RNO-6807877 ARFGAPs stimulate ARF GTPase activity IEA Rattus norvegicus 37565 R-RNO-6809003 https://reactome.org/PathwayBrowser/#/R-RNO-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Rattus norvegicus 37565 R-RNO-6809006 https://reactome.org/PathwayBrowser/#/R-RNO-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Rattus norvegicus 37565 R-RNO-6809010 https://reactome.org/PathwayBrowser/#/R-RNO-6809010 COPI vesicle uncoating IEA Rattus norvegicus 37565 R-RNO-6809011 https://reactome.org/PathwayBrowser/#/R-RNO-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Rattus norvegicus 37565 R-RNO-6811411 https://reactome.org/PathwayBrowser/#/R-RNO-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Rattus norvegicus 37565 R-RNO-6811412 https://reactome.org/PathwayBrowser/#/R-RNO-6811412 Active ARF recruits coatomer to the Golgi IEA Rattus norvegicus 37565 R-RNO-6811414 https://reactome.org/PathwayBrowser/#/R-RNO-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Rattus norvegicus 37565 R-RNO-6811415 https://reactome.org/PathwayBrowser/#/R-RNO-6811415 RAB:GTP recruits GBF1 to the Golgi membrane IEA Rattus norvegicus 37565 R-RNO-6811417 https://reactome.org/PathwayBrowser/#/R-RNO-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Rattus norvegicus 37565 R-RNO-6811418 https://reactome.org/PathwayBrowser/#/R-RNO-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Rattus norvegicus 37565 R-RNO-6811423 https://reactome.org/PathwayBrowser/#/R-RNO-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Rattus norvegicus 37565 R-RNO-6811426 https://reactome.org/PathwayBrowser/#/R-RNO-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Rattus norvegicus 37565 R-RNO-6811427 https://reactome.org/PathwayBrowser/#/R-RNO-6811427 COPI vesicle uncoating at the ER IEA Rattus norvegicus 37565 R-RNO-6811429 https://reactome.org/PathwayBrowser/#/R-RNO-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-6811431 https://reactome.org/PathwayBrowser/#/R-RNO-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Rattus norvegicus 37565 R-RNO-6814086 https://reactome.org/PathwayBrowser/#/R-RNO-6814086 ARFRP1 recruits ARL1 to the TGN IEA Rattus norvegicus 37565 R-RNO-6814088 https://reactome.org/PathwayBrowser/#/R-RNO-6814088 SYS1 binds AcM-ARFRP1 IEA Rattus norvegicus 37565 R-RNO-6814091 https://reactome.org/PathwayBrowser/#/R-RNO-6814091 ARL1 recruits TGN Golgin homodimers IEA Rattus norvegicus 37565 R-RNO-6814094 https://reactome.org/PathwayBrowser/#/R-RNO-6814094 ARL1:GTP binds ARFIP2 IEA Rattus norvegicus 37565 R-RNO-6814096 https://reactome.org/PathwayBrowser/#/R-RNO-6814096 ARL1:GTP binds SCOC IEA Rattus norvegicus 37565 R-RNO-6814549 https://reactome.org/PathwayBrowser/#/R-RNO-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Rattus norvegicus 37565 R-RNO-6814559 https://reactome.org/PathwayBrowser/#/R-RNO-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Rattus norvegicus 37565 R-RNO-6814671 https://reactome.org/PathwayBrowser/#/R-RNO-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Rattus norvegicus 37565 R-RNO-6814675 https://reactome.org/PathwayBrowser/#/R-RNO-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Rattus norvegicus 37565 R-RNO-6814682 https://reactome.org/PathwayBrowser/#/R-RNO-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Rattus norvegicus 37565 R-RNO-6814831 https://reactome.org/PathwayBrowser/#/R-RNO-6814831 TBC1D20 binds RAB1:GTP IEA Rattus norvegicus 37565 R-RNO-6814833 https://reactome.org/PathwayBrowser/#/R-RNO-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Rattus norvegicus 37565 R-RNO-70241 https://reactome.org/PathwayBrowser/#/R-RNO-70241 PCK1 phosphorylates OA to yield PEP IEA Rattus norvegicus 37565 R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Rattus norvegicus 37565 R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Rattus norvegicus 37565 R-RNO-71775 https://reactome.org/PathwayBrowser/#/R-RNO-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Rattus norvegicus 37565 R-RNO-72621 https://reactome.org/PathwayBrowser/#/R-RNO-72621 Ribosomal scanning IEA Rattus norvegicus 37565 R-RNO-72663 https://reactome.org/PathwayBrowser/#/R-RNO-72663 De novo formation of eIF2:GTP IEA Rattus norvegicus 37565 R-RNO-72669 https://reactome.org/PathwayBrowser/#/R-RNO-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Rattus norvegicus 37565 R-RNO-72671 https://reactome.org/PathwayBrowser/#/R-RNO-72671 eIF5B:GTP is hydrolyzed and released IEA Rattus norvegicus 37565 R-RNO-72672 https://reactome.org/PathwayBrowser/#/R-RNO-72672 The 60S subunit joins the translation initiation complex IEA Rattus norvegicus 37565 R-RNO-72691 https://reactome.org/PathwayBrowser/#/R-RNO-72691 Formation of the 43S pre-initiation complex IEA Rattus norvegicus 37565 R-RNO-72697 https://reactome.org/PathwayBrowser/#/R-RNO-72697 Start codon recognition IEA Rattus norvegicus 37565 R-RNO-72722 https://reactome.org/PathwayBrowser/#/R-RNO-72722 eIF2 activation IEA Rattus norvegicus 37565 R-RNO-74059 https://reactome.org/PathwayBrowser/#/R-RNO-74059 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 37565 R-RNO-74885 https://reactome.org/PathwayBrowser/#/R-RNO-74885 GUCYs converts GTP to cGMP IEA Rattus norvegicus 37565 R-RNO-749453 https://reactome.org/PathwayBrowser/#/R-RNO-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Rattus norvegicus 37565 R-RNO-749516 https://reactome.org/PathwayBrowser/#/R-RNO-749516 Mannose-1-phosphate converted to GDP-Mannose TAS Rattus norvegicus 37565 R-RNO-751029 https://reactome.org/PathwayBrowser/#/R-RNO-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Rattus norvegicus 37565 R-RNO-77081 https://reactome.org/PathwayBrowser/#/R-RNO-77081 Formation of the CE:GMP intermediate complex IEA Rattus norvegicus 37565 R-RNO-8847534 https://reactome.org/PathwayBrowser/#/R-RNO-8847534 RAB43 hydrolyses GTP IEA Rattus norvegicus 37565 R-RNO-8847537 https://reactome.org/PathwayBrowser/#/R-RNO-8847537 RAB43:GTP binds USP8NL IEA Rattus norvegicus 37565 R-RNO-8847887 https://reactome.org/PathwayBrowser/#/R-RNO-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Rattus norvegicus 37565 R-RNO-8848618 https://reactome.org/PathwayBrowser/#/R-RNO-8848618 Activation of RAC1 by the PXN:CRK complex IEA Rattus norvegicus 37565 R-RNO-8849082 https://reactome.org/PathwayBrowser/#/R-RNO-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Rattus norvegicus 37565 R-RNO-8849085 https://reactome.org/PathwayBrowser/#/R-RNO-8849085 ARHGAP35 binds RHOA:GTP IEA Rattus norvegicus 37565 R-RNO-8849348 https://reactome.org/PathwayBrowser/#/R-RNO-8849348 RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo IEA Rattus norvegicus 37565 R-RNO-8849350 https://reactome.org/PathwayBrowser/#/R-RNO-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Rattus norvegicus 37565 R-RNO-8849353 https://reactome.org/PathwayBrowser/#/R-RNO-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Rattus norvegicus 37565 R-RNO-8849748 https://reactome.org/PathwayBrowser/#/R-RNO-8849748 The COG complex binds RABs at the Golgi membrane IEA Rattus norvegicus 37565 R-RNO-8850041 https://reactome.org/PathwayBrowser/#/R-RNO-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Rattus norvegicus 37565 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 37565 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 37565 R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 37565 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 37565 R-RNO-8851827 https://reactome.org/PathwayBrowser/#/R-RNO-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Rattus norvegicus 37565 R-RNO-8851877 https://reactome.org/PathwayBrowser/#/R-RNO-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Rattus norvegicus 37565 R-RNO-8851899 https://reactome.org/PathwayBrowser/#/R-RNO-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Rattus norvegicus 37565 R-RNO-8852280 https://reactome.org/PathwayBrowser/#/R-RNO-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Rattus norvegicus 37565 R-RNO-8852298 https://reactome.org/PathwayBrowser/#/R-RNO-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Rattus norvegicus 37565 R-RNO-8852306 https://reactome.org/PathwayBrowser/#/R-RNO-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Rattus norvegicus 37565 R-RNO-8854173 https://reactome.org/PathwayBrowser/#/R-RNO-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Rattus norvegicus 37565 R-RNO-8854182 https://reactome.org/PathwayBrowser/#/R-RNO-8854182 TBC1D17 binds OPTN:RAB8A IEA Rattus norvegicus 37565 R-RNO-8854293 https://reactome.org/PathwayBrowser/#/R-RNO-8854293 TBC1D10A (EPI64) binds ARF6:GTP IEA Rattus norvegicus 37565 R-RNO-8854303 https://reactome.org/PathwayBrowser/#/R-RNO-8854303 TBC1D11 binds RAB6 IEA Rattus norvegicus 37565 R-RNO-8854612 https://reactome.org/PathwayBrowser/#/R-RNO-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Rattus norvegicus 37565 R-RNO-8856808 https://reactome.org/PathwayBrowser/#/R-RNO-8856808 Recruitment of AP-2 complex and clathrin IEA Rattus norvegicus 37565 R-RNO-8865774 https://reactome.org/PathwayBrowser/#/R-RNO-8865774 TTLLs polyglutamylate tubulin IEA Rattus norvegicus 37565 R-RNO-8867370 https://reactome.org/PathwayBrowser/#/R-RNO-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Rattus norvegicus 37565 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus 37565 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 37565 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus 37565 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 37565 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 37565 R-RNO-8875318 https://reactome.org/PathwayBrowser/#/R-RNO-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Rattus norvegicus 37565 R-RNO-8875320 https://reactome.org/PathwayBrowser/#/R-RNO-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Rattus norvegicus 37565 R-RNO-8875568 https://reactome.org/PathwayBrowser/#/R-RNO-8875568 RAPGEF1 activates RAP1 IEA Rattus norvegicus 37565 R-RNO-8875591 https://reactome.org/PathwayBrowser/#/R-RNO-8875591 DOCK7 activates RAC1 IEA Rattus norvegicus 37565 R-RNO-8875659 https://reactome.org/PathwayBrowser/#/R-RNO-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Rattus norvegicus 37565 R-RNO-8875661 https://reactome.org/PathwayBrowser/#/R-RNO-8875661 GGA3 associates with activated MET receptor IEA Rattus norvegicus 37565 R-RNO-8876188 https://reactome.org/PathwayBrowser/#/R-RNO-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Rattus norvegicus 37565 R-RNO-8876190 https://reactome.org/PathwayBrowser/#/R-RNO-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Rattus norvegicus 37565 R-RNO-8876191 https://reactome.org/PathwayBrowser/#/R-RNO-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Rattus norvegicus 37565 R-RNO-8876193 https://reactome.org/PathwayBrowser/#/R-RNO-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Rattus norvegicus 37565 R-RNO-8876454 https://reactome.org/PathwayBrowser/#/R-RNO-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Rattus norvegicus 37565 R-RNO-8876615 https://reactome.org/PathwayBrowser/#/R-RNO-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Rattus norvegicus 37565 R-RNO-8876616 https://reactome.org/PathwayBrowser/#/R-RNO-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Rattus norvegicus 37565 R-RNO-8876837 https://reactome.org/PathwayBrowser/#/R-RNO-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Rattus norvegicus 37565 R-RNO-8877308 https://reactome.org/PathwayBrowser/#/R-RNO-8877308 MADD exchanges GTP for GDP on RAB27 IEA Rattus norvegicus 37565 R-RNO-8877311 https://reactome.org/PathwayBrowser/#/R-RNO-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Rattus norvegicus 37565 R-RNO-8877451 https://reactome.org/PathwayBrowser/#/R-RNO-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Rattus norvegicus 37565 R-RNO-8877475 https://reactome.org/PathwayBrowser/#/R-RNO-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Rattus norvegicus 37565 R-RNO-8877612 https://reactome.org/PathwayBrowser/#/R-RNO-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Rattus norvegicus 37565 R-RNO-8877760 https://reactome.org/PathwayBrowser/#/R-RNO-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Rattus norvegicus 37565 R-RNO-8877813 https://reactome.org/PathwayBrowser/#/R-RNO-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Rattus norvegicus 37565 R-RNO-8877998 https://reactome.org/PathwayBrowser/#/R-RNO-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Rattus norvegicus 37565 R-RNO-8941613 https://reactome.org/PathwayBrowser/#/R-RNO-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-8941618 https://reactome.org/PathwayBrowser/#/R-RNO-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-8941623 https://reactome.org/PathwayBrowser/#/R-RNO-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-8941628 https://reactome.org/PathwayBrowser/#/R-RNO-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 37565 R-RNO-8944454 https://reactome.org/PathwayBrowser/#/R-RNO-8944454 mTORC1 phosphorylates MAF1 IEA Rattus norvegicus 37565 R-RNO-8944457 https://reactome.org/PathwayBrowser/#/R-RNO-8944457 MAF1 translocates to the nucleus IEA Rattus norvegicus 37565 R-RNO-8951490 https://reactome.org/PathwayBrowser/#/R-RNO-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Rattus norvegicus 37565 R-RNO-8951498 https://reactome.org/PathwayBrowser/#/R-RNO-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Rattus norvegicus 37565 R-RNO-8952716 https://reactome.org/PathwayBrowser/#/R-RNO-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Rattus norvegicus 37565 R-RNO-8952726 https://reactome.org/PathwayBrowser/#/R-RNO-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Rattus norvegicus 37565 R-RNO-8964242 https://reactome.org/PathwayBrowser/#/R-RNO-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Rattus norvegicus 37565 R-RNO-8964246 https://reactome.org/PathwayBrowser/#/R-RNO-8964246 BTK in G alpha (12)-BTK complex is activated IEA Rattus norvegicus 37565 R-RNO-8964274 https://reactome.org/PathwayBrowser/#/R-RNO-8964274 G alpha (12) binds BTK IEA Rattus norvegicus 37565 R-RNO-8964280 https://reactome.org/PathwayBrowser/#/R-RNO-8964280 Active Gq binds BTK IEA Rattus norvegicus 37565 R-RNO-8964284 https://reactome.org/PathwayBrowser/#/R-RNO-8964284 BTK in active Gq-BTK complex is activated IEA Rattus norvegicus 37565 R-RNO-8964329 https://reactome.org/PathwayBrowser/#/R-RNO-8964329 G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC IEA Rattus norvegicus 37565 R-RNO-8964333 https://reactome.org/PathwayBrowser/#/R-RNO-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) IEA Rattus norvegicus 37565 R-RNO-8964340 https://reactome.org/PathwayBrowser/#/R-RNO-8964340 Gq-BTK complex dissociates to Active BTK and Gq IEA Rattus norvegicus 37565 R-RNO-8964604 https://reactome.org/PathwayBrowser/#/R-RNO-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Rattus norvegicus 37565 R-RNO-8964614 https://reactome.org/PathwayBrowser/#/R-RNO-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Rattus norvegicus 37565 R-RNO-8980691 https://reactome.org/PathwayBrowser/#/R-RNO-8980691 RHOA GEFs activate RHOA IEA Rattus norvegicus 37565 R-RNO-8981353 https://reactome.org/PathwayBrowser/#/R-RNO-8981353 RASA1 stimulates RAS GTPase activity IEA Rattus norvegicus 37565 R-RNO-8981355 https://reactome.org/PathwayBrowser/#/R-RNO-8981355 RASA1 binds RAS:GTP IEA Rattus norvegicus 37565 R-RNO-8981637 https://reactome.org/PathwayBrowser/#/R-RNO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Rattus norvegicus 37565 R-RNO-8981892 https://reactome.org/PathwayBrowser/#/R-RNO-8981892 Active G alpha (z) binds RGS proteins IEA Rattus norvegicus 37565 R-RNO-8981926 https://reactome.org/PathwayBrowser/#/R-RNO-8981926 RAC1 and CDC42 activate PAK3 IEA Rattus norvegicus 37565 R-RNO-8981931 https://reactome.org/PathwayBrowser/#/R-RNO-8981931 RAC1 and CDC42 activate PAK2 IEA Rattus norvegicus 37565 R-RNO-8982017 https://reactome.org/PathwayBrowser/#/R-RNO-8982017 Active G alpha (q) binds RGS proteins IEA Rattus norvegicus 37565 R-RNO-8982019 https://reactome.org/PathwayBrowser/#/R-RNO-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Rattus norvegicus 37565 R-RNO-8982020 https://reactome.org/PathwayBrowser/#/R-RNO-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Rattus norvegicus 37565 R-RNO-8982021 https://reactome.org/PathwayBrowser/#/R-RNO-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Rattus norvegicus 37565 R-RNO-8982025 https://reactome.org/PathwayBrowser/#/R-RNO-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Rattus norvegicus 37565 R-RNO-8985594 https://reactome.org/PathwayBrowser/#/R-RNO-8985594 MYO9B inactivates RHOA IEA Rattus norvegicus 37565 R-RNO-9013004 https://reactome.org/PathwayBrowser/#/R-RNO-9013004 RHOA binds effectors at the ER membrane IEA Rattus norvegicus 37565 R-RNO-9013006 https://reactome.org/PathwayBrowser/#/R-RNO-9013006 RHOA:GTP translocates to the ER membrane IEA Rattus norvegicus 37565 R-RNO-9013009 https://reactome.org/PathwayBrowser/#/R-RNO-9013009 RHOA binds effectors at the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9013022 https://reactome.org/PathwayBrowser/#/R-RNO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Rattus norvegicus 37565 R-RNO-9013023 https://reactome.org/PathwayBrowser/#/R-RNO-9013023 RHOB GEFs activate RHOB IEA Rattus norvegicus 37565 R-RNO-9013024 https://reactome.org/PathwayBrowser/#/R-RNO-9013024 RHOB binds effectors at the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9013143 https://reactome.org/PathwayBrowser/#/R-RNO-9013143 RAC1 GEFs activate RAC1 IEA Rattus norvegicus 37565 R-RNO-9013144 https://reactome.org/PathwayBrowser/#/R-RNO-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Rattus norvegicus 37565 R-RNO-9013145 https://reactome.org/PathwayBrowser/#/R-RNO-9013145 RAC1 binds effectors at the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9013159 https://reactome.org/PathwayBrowser/#/R-RNO-9013159 CDC42 GEFs activate CDC42 IEA Rattus norvegicus 37565 R-RNO-9013161 https://reactome.org/PathwayBrowser/#/R-RNO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Rattus norvegicus 37565 R-RNO-9013435 https://reactome.org/PathwayBrowser/#/R-RNO-9013435 RHOD auto-activates IEA Rattus norvegicus 37565 R-RNO-9013437 https://reactome.org/PathwayBrowser/#/R-RNO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Rattus norvegicus 37565 R-RNO-9013438 https://reactome.org/PathwayBrowser/#/R-RNO-9013438 RHOD binds effectors at the endosome membrane IEA Rattus norvegicus 37565 R-RNO-9013452 https://reactome.org/PathwayBrowser/#/R-RNO-9013452 RHOD:GTP translocates to the endosome membrane IEA Rattus norvegicus 37565 R-RNO-9014294 https://reactome.org/PathwayBrowser/#/R-RNO-9014294 RAC2 binds effectors at the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9014295 https://reactome.org/PathwayBrowser/#/R-RNO-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Rattus norvegicus 37565 R-RNO-9014296 https://reactome.org/PathwayBrowser/#/R-RNO-9014296 RAC2 GEFs activate RAC2 IEA Rattus norvegicus 37565 R-RNO-9014420 https://reactome.org/PathwayBrowser/#/R-RNO-9014420 RAC2 translocates to the phagocytic vesicle membrane IEA Rattus norvegicus 37565 R-RNO-9014424 https://reactome.org/PathwayBrowser/#/R-RNO-9014424 RAC2 binds effectors at the phagocytic vesicle membrane IEA Rattus norvegicus 37565 R-RNO-9014433 https://reactome.org/PathwayBrowser/#/R-RNO-9014433 RHOG GEFs activate RHOG IEA Rattus norvegicus 37565 R-RNO-9014434 https://reactome.org/PathwayBrowser/#/R-RNO-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Rattus norvegicus 37565 R-RNO-9014449 https://reactome.org/PathwayBrowser/#/R-RNO-9014449 RHOG binds effectors at the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9014454 https://reactome.org/PathwayBrowser/#/R-RNO-9014454 RHOG translocates to the ER membrane IEA Rattus norvegicus 37565 R-RNO-9014467 https://reactome.org/PathwayBrowser/#/R-RNO-9014467 RHOG binds effectors at the ER membrane IEA Rattus norvegicus 37565 R-RNO-9017488 https://reactome.org/PathwayBrowser/#/R-RNO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Rattus norvegicus 37565 R-RNO-9017491 https://reactome.org/PathwayBrowser/#/R-RNO-9017491 RHOJ GEFs activate RHOJ IEA Rattus norvegicus 37565 R-RNO-9018745 https://reactome.org/PathwayBrowser/#/R-RNO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Rattus norvegicus 37565 R-RNO-9018746 https://reactome.org/PathwayBrowser/#/R-RNO-9018746 RHOQ binds effectors at the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9018747 https://reactome.org/PathwayBrowser/#/R-RNO-9018747 RHOQ GEFs activate RHOQ IEA Rattus norvegicus 37565 R-RNO-9018754 https://reactome.org/PathwayBrowser/#/R-RNO-9018754 GDIs bind RHOH IEA Rattus norvegicus 37565 R-RNO-9018756 https://reactome.org/PathwayBrowser/#/R-RNO-9018756 RHOH binds GTP IEA Rattus norvegicus 37565 R-RNO-9018758 https://reactome.org/PathwayBrowser/#/R-RNO-9018758 RHOH binds effectors at the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9018766 https://reactome.org/PathwayBrowser/#/R-RNO-9018766 RHOU binds effectors at the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9018768 https://reactome.org/PathwayBrowser/#/R-RNO-9018768 RHOU auto-activates IEA Rattus norvegicus 37565 R-RNO-9018774 https://reactome.org/PathwayBrowser/#/R-RNO-9018774 RHOBTB1 binds GTP IEA Rattus norvegicus 37565 R-RNO-9018778 https://reactome.org/PathwayBrowser/#/R-RNO-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Rattus norvegicus 37565 R-RNO-9018785 https://reactome.org/PathwayBrowser/#/R-RNO-9018785 RHOBTB2 binds GTP IEA Rattus norvegicus 37565 R-RNO-9018787 https://reactome.org/PathwayBrowser/#/R-RNO-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Rattus norvegicus 37565 R-RNO-9018794 https://reactome.org/PathwayBrowser/#/R-RNO-9018794 RHOV binds effectors at the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9018798 https://reactome.org/PathwayBrowser/#/R-RNO-9018798 RHOV binds GTP IEA Rattus norvegicus 37565 R-RNO-9018824 https://reactome.org/PathwayBrowser/#/R-RNO-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Rattus norvegicus 37565 R-RNO-9018826 https://reactome.org/PathwayBrowser/#/R-RNO-9018826 RHOT2 hydrolyzes GTP IEA Rattus norvegicus 37565 R-RNO-9018836 https://reactome.org/PathwayBrowser/#/R-RNO-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Rattus norvegicus 37565 R-RNO-9030763 https://reactome.org/PathwayBrowser/#/R-RNO-9030763 Ntrk2 activates Ras signaling through Shc1 TAS Rattus norvegicus 37565 R-RNO-9032798 https://reactome.org/PathwayBrowser/#/R-RNO-9032798 DOCK3 activates RAC1 IEA Rattus norvegicus 37565 R-RNO-939265 https://reactome.org/PathwayBrowser/#/R-RNO-939265 Activation of Rap1 by membrane-associated GEFs IEA Rattus norvegicus 37565 R-RNO-947535 https://reactome.org/PathwayBrowser/#/R-RNO-947535 Cyclisation of GTP to precursor Z IEA Rattus norvegicus 37565 R-RNO-9607304 https://reactome.org/PathwayBrowser/#/R-RNO-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Rattus norvegicus 37565 R-RNO-9610152 https://reactome.org/PathwayBrowser/#/R-RNO-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Rattus norvegicus 37565 R-RNO-9610153 https://reactome.org/PathwayBrowser/#/R-RNO-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Rattus norvegicus 37565 R-RNO-9610154 https://reactome.org/PathwayBrowser/#/R-RNO-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Rattus norvegicus 37565 R-RNO-9610156 https://reactome.org/PathwayBrowser/#/R-RNO-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Rattus norvegicus 37565 R-RNO-9610163 https://reactome.org/PathwayBrowser/#/R-RNO-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Rattus norvegicus 37565 R-RNO-9612988 https://reactome.org/PathwayBrowser/#/R-RNO-9612988 Rap1-GTP phosphorylates Raf1 TAS Rattus norvegicus 37565 R-RNO-9619811 https://reactome.org/PathwayBrowser/#/R-RNO-9619811 p-S516-Arhgef7 activates Rac1 TAS Rattus norvegicus 37565 R-RNO-9624845 https://reactome.org/PathwayBrowser/#/R-RNO-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Rattus norvegicus 37565 R-RNO-9624876 https://reactome.org/PathwayBrowser/#/R-RNO-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Rattus norvegicus 37565 R-RNO-9624893 https://reactome.org/PathwayBrowser/#/R-RNO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Rattus norvegicus 37565 R-RNO-9626036 https://reactome.org/PathwayBrowser/#/R-RNO-9626036 Eef1a1 binds GTP TAS Rattus norvegicus 37565 R-RNO-9626064 https://reactome.org/PathwayBrowser/#/R-RNO-9626064 Eef1a1:GTP translocates from lysosomal membrane to cytosol TAS Rattus norvegicus 37565 R-RNO-9626848 https://reactome.org/PathwayBrowser/#/R-RNO-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Rattus norvegicus 37565 R-RNO-9632910 https://reactome.org/PathwayBrowser/#/R-RNO-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Rattus norvegicus 37565 R-RNO-9632918 https://reactome.org/PathwayBrowser/#/R-RNO-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Rattus norvegicus 37565 R-RNO-9639286 https://reactome.org/PathwayBrowser/#/R-RNO-9639286 RRAGC,D exchanges GTP for GDP IEA Rattus norvegicus 37565 R-RNO-9640167 https://reactome.org/PathwayBrowser/#/R-RNO-9640167 RRAGA,B exchanges GDP for GTP IEA Rattus norvegicus 37565 R-RNO-9640168 https://reactome.org/PathwayBrowser/#/R-RNO-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Rattus norvegicus 37565 R-RNO-9640195 https://reactome.org/PathwayBrowser/#/R-RNO-9640195 RRAGA,B hydrolyzes GTP IEA Rattus norvegicus 37565 R-RNO-9645598 https://reactome.org/PathwayBrowser/#/R-RNO-9645598 RRAGC,D hydrolyzes GTP IEA Rattus norvegicus 37565 R-RNO-9645608 https://reactome.org/PathwayBrowser/#/R-RNO-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Rattus norvegicus 37565 R-RNO-9646468 https://reactome.org/PathwayBrowser/#/R-RNO-9646468 mTORC1 binds RHEB:GTP IEA Rattus norvegicus 37565 R-RNO-9646679 https://reactome.org/PathwayBrowser/#/R-RNO-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Rattus norvegicus 37565 R-RNO-9646685 https://reactome.org/PathwayBrowser/#/R-RNO-9646685 Aggresome dissociates from dynein and microtubule IEA Rattus norvegicus 37565 R-RNO-9648017 https://reactome.org/PathwayBrowser/#/R-RNO-9648017 EML4 binds to microtubules IEA Rattus norvegicus 37565 R-RNO-9648114 https://reactome.org/PathwayBrowser/#/R-RNO-9648114 EML4 recruits NUDC to mitotic spindle IEA Rattus norvegicus 37565 R-RNO-9649735 https://reactome.org/PathwayBrowser/#/R-RNO-9649735 Intrinsic nucleotide exchange on RAS IEA Rattus norvegicus 37565 R-RNO-9649736 https://reactome.org/PathwayBrowser/#/R-RNO-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Rattus norvegicus 37565 R-RNO-9653108 https://reactome.org/PathwayBrowser/#/R-RNO-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Rattus norvegicus 37565 R-RNO-9654523 https://reactome.org/PathwayBrowser/#/R-RNO-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Rattus norvegicus 37565 R-RNO-9654533 https://reactome.org/PathwayBrowser/#/R-RNO-9654533 KRAS4B recycles to the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9657599 https://reactome.org/PathwayBrowser/#/R-RNO-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Rattus norvegicus 37565 R-RNO-9657603 https://reactome.org/PathwayBrowser/#/R-RNO-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Rattus norvegicus 37565 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 37565 R-RNO-9657608 https://reactome.org/PathwayBrowser/#/R-RNO-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Rattus norvegicus 37565 R-RNO-9658253 https://reactome.org/PathwayBrowser/#/R-RNO-9658253 RAS:GTP binds PI3K IEA Rattus norvegicus 37565 R-RNO-9658445 https://reactome.org/PathwayBrowser/#/R-RNO-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Rattus norvegicus 37565 R-RNO-9660557 https://reactome.org/PathwayBrowser/#/R-RNO-9660557 RAS:GTP binds RAL GDS proteins IEA Rattus norvegicus 37565 R-RNO-9668419 https://reactome.org/PathwayBrowser/#/R-RNO-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Rattus norvegicus 37565 R-RNO-9690493 https://reactome.org/PathwayBrowser/#/R-RNO-9690493 RHOB binds effectors on endosomes IEA Rattus norvegicus 37565 R-RNO-9690494 https://reactome.org/PathwayBrowser/#/R-RNO-9690494 RHOB translocates to the endosome membrane IEA Rattus norvegicus 37565 R-RNO-9691168 https://reactome.org/PathwayBrowser/#/R-RNO-9691168 RAC1 translocates to the endoplasmic reticulum membrane IEA Rattus norvegicus 37565 R-RNO-9691174 https://reactome.org/PathwayBrowser/#/R-RNO-9691174 RAC1 binds effectors at the ER membrane IEA Rattus norvegicus 37565 R-RNO-9692800 https://reactome.org/PathwayBrowser/#/R-RNO-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Rattus norvegicus 37565 R-RNO-9692809 https://reactome.org/PathwayBrowser/#/R-RNO-9692809 CDC42 binds effectors at the ER membrane IEA Rattus norvegicus 37565 R-RNO-9693111 https://reactome.org/PathwayBrowser/#/R-RNO-9693111 RHOF auto-activates IEA Rattus norvegicus 37565 R-RNO-9693125 https://reactome.org/PathwayBrowser/#/R-RNO-9693125 RHOF binds effectors at the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9693198 https://reactome.org/PathwayBrowser/#/R-RNO-9693198 RHOD binds effectors at the plasma membrane IEA Rattus norvegicus 37565 R-RNO-9693207 https://reactome.org/PathwayBrowser/#/R-RNO-9693207 RHOD translocates to the mitochondrial outer membrane IEA Rattus norvegicus 37565 R-RNO-9693214 https://reactome.org/PathwayBrowser/#/R-RNO-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Rattus norvegicus 37565 R-RNO-9693243 https://reactome.org/PathwayBrowser/#/R-RNO-9693243 RHOD translocates to the Golgi membrane IEA Rattus norvegicus 37565 R-RNO-9693250 https://reactome.org/PathwayBrowser/#/R-RNO-9693250 RHOD binds effectors at the Golgi membrane IEA Rattus norvegicus 37565 R-RNO-9693282 https://reactome.org/PathwayBrowser/#/R-RNO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Rattus norvegicus 37565 R-RNO-9696266 https://reactome.org/PathwayBrowser/#/R-RNO-9696266 RND2 binds effectors IEA Rattus norvegicus 37565 R-RNO-9696267 https://reactome.org/PathwayBrowser/#/R-RNO-9696267 RND3 binds GTP IEA Rattus norvegicus 37565 R-RNO-9696268 https://reactome.org/PathwayBrowser/#/R-RNO-9696268 RND3 binds effectors IEA Rattus norvegicus 37565 R-RNO-9696271 https://reactome.org/PathwayBrowser/#/R-RNO-9696271 RND1 binds effectors IEA Rattus norvegicus 37565 R-RNO-9696274 https://reactome.org/PathwayBrowser/#/R-RNO-9696274 RND1 binds GTP IEA Rattus norvegicus 37565 R-RNO-9696275 https://reactome.org/PathwayBrowser/#/R-RNO-9696275 RND2 binds GTP IEA Rattus norvegicus 37565 R-RNO-9713234 https://reactome.org/PathwayBrowser/#/R-RNO-9713234 Gnal exchanges GDP for GTP TAS Rattus norvegicus 37565 R-RNO-9713735 https://reactome.org/PathwayBrowser/#/R-RNO-9713735 Adcy3:Gnal:GTP converts ATP to cAMP TAS Rattus norvegicus 37565 R-RNO-9714477 https://reactome.org/PathwayBrowser/#/R-RNO-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Rattus norvegicus 37565 R-RNO-9714480 https://reactome.org/PathwayBrowser/#/R-RNO-9714480 RAC2 translocates to the mitochondrial membrane IEA Rattus norvegicus 37565 R-RNO-9714481 https://reactome.org/PathwayBrowser/#/R-RNO-9714481 RAC2 binds effectors at the ER membrane IEA Rattus norvegicus 37565 R-RNO-9714483 https://reactome.org/PathwayBrowser/#/R-RNO-9714483 RAC2 translocates to the ER membrane IEA Rattus norvegicus 37565 R-RNO-983259 https://reactome.org/PathwayBrowser/#/R-RNO-983259 Kinesins move along microtubules consuming ATP IEA Rattus norvegicus 37565 R-RNO-983266 https://reactome.org/PathwayBrowser/#/R-RNO-983266 Kinesins bind microtubules IEA Rattus norvegicus 37565 R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus 37565 R-RNO-983424 https://reactome.org/PathwayBrowser/#/R-RNO-983424 Budding of COPII coated vesicle IEA Rattus norvegicus 37565 R-RNO-983425 https://reactome.org/PathwayBrowser/#/R-RNO-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Rattus norvegicus 37565 R-RNO-9836404 https://reactome.org/PathwayBrowser/#/R-RNO-9836404 p-PKR dimer phosphorylates MAPT IEA Rattus norvegicus 37565 R-SCE-1008248 https://reactome.org/PathwayBrowser/#/R-SCE-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Saccharomyces cerevisiae 37565 R-SCE-111524 https://reactome.org/PathwayBrowser/#/R-SCE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Saccharomyces cerevisiae 37565 R-SCE-111879 https://reactome.org/PathwayBrowser/#/R-SCE-111879 PIP2 hydrolysis IEA Saccharomyces cerevisiae 37565 R-SCE-112037 https://reactome.org/PathwayBrowser/#/R-SCE-112037 Inactivation of PLC beta IEA Saccharomyces cerevisiae 37565 R-SCE-114688 https://reactome.org/PathwayBrowser/#/R-SCE-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Saccharomyces cerevisiae 37565 R-SCE-141667 https://reactome.org/PathwayBrowser/#/R-SCE-141667 GTP bound eRF3:eRF1 complex binds the peptidyl-tRNA:mRNA:Ribosome complex TAS Saccharomyces cerevisiae 37565 R-SCE-141687 https://reactome.org/PathwayBrowser/#/R-SCE-141687 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex TAS Saccharomyces cerevisiae 37565 R-SCE-1474146 https://reactome.org/PathwayBrowser/#/R-SCE-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Saccharomyces cerevisiae 37565 R-SCE-156808 https://reactome.org/PathwayBrowser/#/R-SCE-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Saccharomyces cerevisiae 37565 R-SCE-156823 https://reactome.org/PathwayBrowser/#/R-SCE-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Saccharomyces cerevisiae 37565 R-SCE-156913 https://reactome.org/PathwayBrowser/#/R-SCE-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Saccharomyces cerevisiae 37565 R-SCE-156930 https://reactome.org/PathwayBrowser/#/R-SCE-156930 GTP-binding activates eEF2 IEA Saccharomyces cerevisiae 37565 R-SCE-157849 https://reactome.org/PathwayBrowser/#/R-SCE-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Saccharomyces cerevisiae 37565 R-SCE-165195 https://reactome.org/PathwayBrowser/#/R-SCE-165195 GTP loading by Rheb IEA Saccharomyces cerevisiae 37565 R-SCE-167415 https://reactome.org/PathwayBrowser/#/R-SCE-167415 G-protein alpha subunit is inactivated IEA Saccharomyces cerevisiae 37565 R-SCE-2029454 https://reactome.org/PathwayBrowser/#/R-SCE-2029454 Autophosphorylation of PAK1 IEA Saccharomyces cerevisiae 37565 R-SCE-2029456 https://reactome.org/PathwayBrowser/#/R-SCE-2029456 RAC1 and CDC42 activate PAK1 IEA Saccharomyces cerevisiae 37565 R-SCE-203977 https://reactome.org/PathwayBrowser/#/R-SCE-203977 SAR1 Activation And Membrane Binding IEA Saccharomyces cerevisiae 37565 R-SCE-203979 https://reactome.org/PathwayBrowser/#/R-SCE-203979 Coat Assembly IEA Saccharomyces cerevisiae 37565 R-SCE-204008 https://reactome.org/PathwayBrowser/#/R-SCE-204008 SEC31:SEC13 and v-SNARE recruitment IEA Saccharomyces cerevisiae 37565 R-SCE-2214351 https://reactome.org/PathwayBrowser/#/R-SCE-2214351 PLK1 phosphorylates GORASP1 IEA Saccharomyces cerevisiae 37565 R-SCE-350769 https://reactome.org/PathwayBrowser/#/R-SCE-350769 trans-Golgi Network Coat Activation IEA Saccharomyces cerevisiae 37565 R-SCE-354173 https://reactome.org/PathwayBrowser/#/R-SCE-354173 Activation of Rap1 by cytosolic GEFs IEA Saccharomyces cerevisiae 37565 R-SCE-381727 https://reactome.org/PathwayBrowser/#/R-SCE-381727 RAP1A exchanges GDP for GTP IEA Saccharomyces cerevisiae 37565 R-SCE-389788 https://reactome.org/PathwayBrowser/#/R-SCE-389788 Activation of PAKs by RAC1 and CDC42 IEA Saccharomyces cerevisiae 37565 R-SCE-399998 https://reactome.org/PathwayBrowser/#/R-SCE-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Saccharomyces cerevisiae 37565 R-SCE-418574 https://reactome.org/PathwayBrowser/#/R-SCE-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Saccharomyces cerevisiae 37565 R-SCE-418582 https://reactome.org/PathwayBrowser/#/R-SCE-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Saccharomyces cerevisiae 37565 R-SCE-419166 https://reactome.org/PathwayBrowser/#/R-SCE-419166 GEFs activate RhoA,B,C IEA Saccharomyces cerevisiae 37565 R-SCE-428941 https://reactome.org/PathwayBrowser/#/R-SCE-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Saccharomyces cerevisiae 37565 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 37565 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 37565 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 37565 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 37565 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 37565 R-SCE-5623508 https://reactome.org/PathwayBrowser/#/R-SCE-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Saccharomyces cerevisiae 37565 R-SCE-5623622 https://reactome.org/PathwayBrowser/#/R-SCE-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Saccharomyces cerevisiae 37565 R-SCE-5623632 https://reactome.org/PathwayBrowser/#/R-SCE-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Saccharomyces cerevisiae 37565 R-SCE-5623667 https://reactome.org/PathwayBrowser/#/R-SCE-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Saccharomyces cerevisiae 37565 R-SCE-5626469 https://reactome.org/PathwayBrowser/#/R-SCE-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Saccharomyces cerevisiae 37565 R-SCE-5626507 https://reactome.org/PathwayBrowser/#/R-SCE-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Saccharomyces cerevisiae 37565 R-SCE-5627775 https://reactome.org/PathwayBrowser/#/R-SCE-5627775 Autophosphorylation of PAK1,2,3 IEA Saccharomyces cerevisiae 37565 R-SCE-5638014 https://reactome.org/PathwayBrowser/#/R-SCE-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Saccharomyces cerevisiae 37565 R-SCE-5653957 https://reactome.org/PathwayBrowser/#/R-SCE-5653957 Rag dimer formation IEA Saccharomyces cerevisiae 37565 R-SCE-5694409 https://reactome.org/PathwayBrowser/#/R-SCE-5694409 Nucleotide exchange on RAB1 IEA Saccharomyces cerevisiae 37565 R-SCE-5694441 https://reactome.org/PathwayBrowser/#/R-SCE-5694441 CSNK1D phosphorylates SEC23 IEA Saccharomyces cerevisiae 37565 R-SCE-5694522 https://reactome.org/PathwayBrowser/#/R-SCE-5694522 Inner coat assembly and cargo binding IEA Saccharomyces cerevisiae 37565 R-SCE-5694527 https://reactome.org/PathwayBrowser/#/R-SCE-5694527 Loss of SAR1B GTPase IEA Saccharomyces cerevisiae 37565 R-SCE-6800138 https://reactome.org/PathwayBrowser/#/R-SCE-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Saccharomyces cerevisiae 37565 R-SCE-6807864 https://reactome.org/PathwayBrowser/#/R-SCE-6807864 RAB1:GTP recruits GBF1 to the ERGIC IEA Saccharomyces cerevisiae 37565 R-SCE-6807866 https://reactome.org/PathwayBrowser/#/R-SCE-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Saccharomyces cerevisiae 37565 R-SCE-6807868 https://reactome.org/PathwayBrowser/#/R-SCE-6807868 GBF1 stimulates ARF nucleotide exchange IEA Saccharomyces cerevisiae 37565 R-SCE-6807872 https://reactome.org/PathwayBrowser/#/R-SCE-6807872 Active ARF recruits coatomer IEA Saccharomyces cerevisiae 37565 R-SCE-6807877 https://reactome.org/PathwayBrowser/#/R-SCE-6807877 ARFGAPs stimulate ARF GTPase activity IEA Saccharomyces cerevisiae 37565 R-SCE-6811411 https://reactome.org/PathwayBrowser/#/R-SCE-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Saccharomyces cerevisiae 37565 R-SCE-6811412 https://reactome.org/PathwayBrowser/#/R-SCE-6811412 Active ARF recruits coatomer to the Golgi IEA Saccharomyces cerevisiae 37565 R-SCE-6811414 https://reactome.org/PathwayBrowser/#/R-SCE-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Saccharomyces cerevisiae 37565 R-SCE-6811415 https://reactome.org/PathwayBrowser/#/R-SCE-6811415 RAB:GTP recruits GBF1 to the Golgi membrane IEA Saccharomyces cerevisiae 37565 R-SCE-6811417 https://reactome.org/PathwayBrowser/#/R-SCE-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Saccharomyces cerevisiae 37565 R-SCE-6811418 https://reactome.org/PathwayBrowser/#/R-SCE-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Saccharomyces cerevisiae 37565 R-SCE-6811427 https://reactome.org/PathwayBrowser/#/R-SCE-6811427 COPI vesicle uncoating at the ER IEA Saccharomyces cerevisiae 37565 R-SCE-6811429 https://reactome.org/PathwayBrowser/#/R-SCE-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Saccharomyces cerevisiae 37565 R-SCE-6814086 https://reactome.org/PathwayBrowser/#/R-SCE-6814086 ARFRP1 recruits ARL1 to the TGN IEA Saccharomyces cerevisiae 37565 R-SCE-6814088 https://reactome.org/PathwayBrowser/#/R-SCE-6814088 SYS1 binds AcM-ARFRP1 IEA Saccharomyces cerevisiae 37565 R-SCE-6814091 https://reactome.org/PathwayBrowser/#/R-SCE-6814091 ARL1 recruits TGN Golgin homodimers IEA Saccharomyces cerevisiae 37565 R-SCE-6814831 https://reactome.org/PathwayBrowser/#/R-SCE-6814831 TBC1D20 binds RAB1:GTP IEA Saccharomyces cerevisiae 37565 R-SCE-6814833 https://reactome.org/PathwayBrowser/#/R-SCE-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Saccharomyces cerevisiae 37565 R-SCE-72621 https://reactome.org/PathwayBrowser/#/R-SCE-72621 Ribosomal scanning IEA Saccharomyces cerevisiae 37565 R-SCE-72663 https://reactome.org/PathwayBrowser/#/R-SCE-72663 De novo formation of eIF2:GTP IEA Saccharomyces cerevisiae 37565 R-SCE-72669 https://reactome.org/PathwayBrowser/#/R-SCE-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Saccharomyces cerevisiae 37565 R-SCE-72671 https://reactome.org/PathwayBrowser/#/R-SCE-72671 eIF5B:GTP is hydrolyzed and released IEA Saccharomyces cerevisiae 37565 R-SCE-72672 https://reactome.org/PathwayBrowser/#/R-SCE-72672 The 60S subunit joins the translation initiation complex IEA Saccharomyces cerevisiae 37565 R-SCE-72691 https://reactome.org/PathwayBrowser/#/R-SCE-72691 Formation of the 43S pre-initiation complex IEA Saccharomyces cerevisiae 37565 R-SCE-72697 https://reactome.org/PathwayBrowser/#/R-SCE-72697 Start codon recognition IEA Saccharomyces cerevisiae 37565 R-SCE-72722 https://reactome.org/PathwayBrowser/#/R-SCE-72722 eIF2 activation IEA Saccharomyces cerevisiae 37565 R-SCE-77081 https://reactome.org/PathwayBrowser/#/R-SCE-77081 Formation of the CE:GMP intermediate complex IEA Saccharomyces cerevisiae 37565 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 37565 R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 37565 R-SCE-8875318 https://reactome.org/PathwayBrowser/#/R-SCE-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Saccharomyces cerevisiae 37565 R-SCE-8875320 https://reactome.org/PathwayBrowser/#/R-SCE-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Saccharomyces cerevisiae 37565 R-SCE-8876190 https://reactome.org/PathwayBrowser/#/R-SCE-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Saccharomyces cerevisiae 37565 R-SCE-8876193 https://reactome.org/PathwayBrowser/#/R-SCE-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Saccharomyces cerevisiae 37565 R-SCE-8877311 https://reactome.org/PathwayBrowser/#/R-SCE-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Saccharomyces cerevisiae 37565 R-SCE-8877451 https://reactome.org/PathwayBrowser/#/R-SCE-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Saccharomyces cerevisiae 37565 R-SCE-8877475 https://reactome.org/PathwayBrowser/#/R-SCE-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Saccharomyces cerevisiae 37565 R-SCE-8981637 https://reactome.org/PathwayBrowser/#/R-SCE-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Saccharomyces cerevisiae 37565 R-SCE-8981892 https://reactome.org/PathwayBrowser/#/R-SCE-8981892 Active G alpha (z) binds RGS proteins IEA Saccharomyces cerevisiae 37565 R-SCE-8981926 https://reactome.org/PathwayBrowser/#/R-SCE-8981926 RAC1 and CDC42 activate PAK3 IEA Saccharomyces cerevisiae 37565 R-SCE-8981931 https://reactome.org/PathwayBrowser/#/R-SCE-8981931 RAC1 and CDC42 activate PAK2 IEA Saccharomyces cerevisiae 37565 R-SCE-8982017 https://reactome.org/PathwayBrowser/#/R-SCE-8982017 Active G alpha (q) binds RGS proteins IEA Saccharomyces cerevisiae 37565 R-SCE-8982019 https://reactome.org/PathwayBrowser/#/R-SCE-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Saccharomyces cerevisiae 37565 R-SCE-8982020 https://reactome.org/PathwayBrowser/#/R-SCE-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Saccharomyces cerevisiae 37565 R-SCE-8982021 https://reactome.org/PathwayBrowser/#/R-SCE-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Saccharomyces cerevisiae 37565 R-SCE-8982025 https://reactome.org/PathwayBrowser/#/R-SCE-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Saccharomyces cerevisiae 37565 R-SCE-9013006 https://reactome.org/PathwayBrowser/#/R-SCE-9013006 RHOA:GTP translocates to the ER membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9013009 https://reactome.org/PathwayBrowser/#/R-SCE-9013009 RHOA binds effectors at the plasma membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9013022 https://reactome.org/PathwayBrowser/#/R-SCE-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Saccharomyces cerevisiae 37565 R-SCE-9013024 https://reactome.org/PathwayBrowser/#/R-SCE-9013024 RHOB binds effectors at the plasma membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9013110 https://reactome.org/PathwayBrowser/#/R-SCE-9013110 RHOC binds effectors at the plasma membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9013111 https://reactome.org/PathwayBrowser/#/R-SCE-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Saccharomyces cerevisiae 37565 R-SCE-9013159 https://reactome.org/PathwayBrowser/#/R-SCE-9013159 CDC42 GEFs activate CDC42 IEA Saccharomyces cerevisiae 37565 R-SCE-9013161 https://reactome.org/PathwayBrowser/#/R-SCE-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Saccharomyces cerevisiae 37565 R-SCE-9013435 https://reactome.org/PathwayBrowser/#/R-SCE-9013435 RHOD auto-activates IEA Saccharomyces cerevisiae 37565 R-SCE-9013437 https://reactome.org/PathwayBrowser/#/R-SCE-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Saccharomyces cerevisiae 37565 R-SCE-9013452 https://reactome.org/PathwayBrowser/#/R-SCE-9013452 RHOD:GTP translocates to the endosome membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9017488 https://reactome.org/PathwayBrowser/#/R-SCE-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Saccharomyces cerevisiae 37565 R-SCE-9018745 https://reactome.org/PathwayBrowser/#/R-SCE-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Saccharomyces cerevisiae 37565 R-SCE-9018746 https://reactome.org/PathwayBrowser/#/R-SCE-9018746 RHOQ binds effectors at the plasma membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9018747 https://reactome.org/PathwayBrowser/#/R-SCE-9018747 RHOQ GEFs activate RHOQ IEA Saccharomyces cerevisiae 37565 R-SCE-9018766 https://reactome.org/PathwayBrowser/#/R-SCE-9018766 RHOU binds effectors at the plasma membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9018768 https://reactome.org/PathwayBrowser/#/R-SCE-9018768 RHOU auto-activates IEA Saccharomyces cerevisiae 37565 R-SCE-9018794 https://reactome.org/PathwayBrowser/#/R-SCE-9018794 RHOV binds effectors at the plasma membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9018798 https://reactome.org/PathwayBrowser/#/R-SCE-9018798 RHOV binds GTP IEA Saccharomyces cerevisiae 37565 R-SCE-9018814 https://reactome.org/PathwayBrowser/#/R-SCE-9018814 RHOT1 hydrolyzes GTP IEA Saccharomyces cerevisiae 37565 R-SCE-9018815 https://reactome.org/PathwayBrowser/#/R-SCE-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9018824 https://reactome.org/PathwayBrowser/#/R-SCE-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9018826 https://reactome.org/PathwayBrowser/#/R-SCE-9018826 RHOT2 hydrolyzes GTP IEA Saccharomyces cerevisiae 37565 R-SCE-9018836 https://reactome.org/PathwayBrowser/#/R-SCE-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Saccharomyces cerevisiae 37565 R-SCE-939265 https://reactome.org/PathwayBrowser/#/R-SCE-939265 Activation of Rap1 by membrane-associated GEFs IEA Saccharomyces cerevisiae 37565 R-SCE-9624845 https://reactome.org/PathwayBrowser/#/R-SCE-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Saccharomyces cerevisiae 37565 R-SCE-9624876 https://reactome.org/PathwayBrowser/#/R-SCE-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Saccharomyces cerevisiae 37565 R-SCE-9624893 https://reactome.org/PathwayBrowser/#/R-SCE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Saccharomyces cerevisiae 37565 R-SCE-9639286 https://reactome.org/PathwayBrowser/#/R-SCE-9639286 RRAGC,D exchanges GTP for GDP IEA Saccharomyces cerevisiae 37565 R-SCE-9640195 https://reactome.org/PathwayBrowser/#/R-SCE-9640195 RRAGA,B hydrolyzes GTP IEA Saccharomyces cerevisiae 37565 R-SCE-9645598 https://reactome.org/PathwayBrowser/#/R-SCE-9645598 RRAGC,D hydrolyzes GTP IEA Saccharomyces cerevisiae 37565 R-SCE-9645608 https://reactome.org/PathwayBrowser/#/R-SCE-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Saccharomyces cerevisiae 37565 R-SCE-9646468 https://reactome.org/PathwayBrowser/#/R-SCE-9646468 mTORC1 binds RHEB:GTP IEA Saccharomyces cerevisiae 37565 R-SCE-9690494 https://reactome.org/PathwayBrowser/#/R-SCE-9690494 RHOB translocates to the endosome membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9692800 https://reactome.org/PathwayBrowser/#/R-SCE-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9693111 https://reactome.org/PathwayBrowser/#/R-SCE-9693111 RHOF auto-activates IEA Saccharomyces cerevisiae 37565 R-SCE-9693198 https://reactome.org/PathwayBrowser/#/R-SCE-9693198 RHOD binds effectors at the plasma membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9693207 https://reactome.org/PathwayBrowser/#/R-SCE-9693207 RHOD translocates to the mitochondrial outer membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9693214 https://reactome.org/PathwayBrowser/#/R-SCE-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9693243 https://reactome.org/PathwayBrowser/#/R-SCE-9693243 RHOD translocates to the Golgi membrane IEA Saccharomyces cerevisiae 37565 R-SCE-9693282 https://reactome.org/PathwayBrowser/#/R-SCE-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Saccharomyces cerevisiae 37565 R-SCE-9696266 https://reactome.org/PathwayBrowser/#/R-SCE-9696266 RND2 binds effectors IEA Saccharomyces cerevisiae 37565 R-SCE-9696267 https://reactome.org/PathwayBrowser/#/R-SCE-9696267 RND3 binds GTP IEA Saccharomyces cerevisiae 37565 R-SCE-9696271 https://reactome.org/PathwayBrowser/#/R-SCE-9696271 RND1 binds effectors IEA Saccharomyces cerevisiae 37565 R-SCE-9696274 https://reactome.org/PathwayBrowser/#/R-SCE-9696274 RND1 binds GTP IEA Saccharomyces cerevisiae 37565 R-SCE-9696275 https://reactome.org/PathwayBrowser/#/R-SCE-9696275 RND2 binds GTP IEA Saccharomyces cerevisiae 37565 R-SCE-9714361 https://reactome.org/PathwayBrowser/#/R-SCE-9714361 RHOC activates endoplasmic reticulum effectors IEA Saccharomyces cerevisiae 37565 R-SCE-9714363 https://reactome.org/PathwayBrowser/#/R-SCE-9714363 RHOC translocates to the endoplasmic reticulum membrane IEA Saccharomyces cerevisiae 37565 R-SPO-111524 https://reactome.org/PathwayBrowser/#/R-SPO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Schizosaccharomyces pombe 37565 R-SPO-111879 https://reactome.org/PathwayBrowser/#/R-SPO-111879 PIP2 hydrolysis IEA Schizosaccharomyces pombe 37565 R-SPO-112037 https://reactome.org/PathwayBrowser/#/R-SPO-112037 Inactivation of PLC beta IEA Schizosaccharomyces pombe 37565 R-SPO-114688 https://reactome.org/PathwayBrowser/#/R-SPO-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Schizosaccharomyces pombe 37565 R-SPO-1474146 https://reactome.org/PathwayBrowser/#/R-SPO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Schizosaccharomyces pombe 37565 R-SPO-156823 https://reactome.org/PathwayBrowser/#/R-SPO-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Schizosaccharomyces pombe 37565 R-SPO-156913 https://reactome.org/PathwayBrowser/#/R-SPO-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Schizosaccharomyces pombe 37565 R-SPO-156930 https://reactome.org/PathwayBrowser/#/R-SPO-156930 GTP-binding activates eEF2 IEA Schizosaccharomyces pombe 37565 R-SPO-157849 https://reactome.org/PathwayBrowser/#/R-SPO-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Schizosaccharomyces pombe 37565 R-SPO-165195 https://reactome.org/PathwayBrowser/#/R-SPO-165195 GTP loading by Rheb IEA Schizosaccharomyces pombe 37565 R-SPO-167415 https://reactome.org/PathwayBrowser/#/R-SPO-167415 G-protein alpha subunit is inactivated IEA Schizosaccharomyces pombe 37565 R-SPO-2029454 https://reactome.org/PathwayBrowser/#/R-SPO-2029454 Autophosphorylation of PAK1 IEA Schizosaccharomyces pombe 37565 R-SPO-2029456 https://reactome.org/PathwayBrowser/#/R-SPO-2029456 RAC1 and CDC42 activate PAK1 IEA Schizosaccharomyces pombe 37565 R-SPO-203977 https://reactome.org/PathwayBrowser/#/R-SPO-203977 SAR1 Activation And Membrane Binding IEA Schizosaccharomyces pombe 37565 R-SPO-203979 https://reactome.org/PathwayBrowser/#/R-SPO-203979 Coat Assembly IEA Schizosaccharomyces pombe 37565 R-SPO-204008 https://reactome.org/PathwayBrowser/#/R-SPO-204008 SEC31:SEC13 and v-SNARE recruitment IEA Schizosaccharomyces pombe 37565 R-SPO-2214351 https://reactome.org/PathwayBrowser/#/R-SPO-2214351 PLK1 phosphorylates GORASP1 IEA Schizosaccharomyces pombe 37565 R-SPO-350769 https://reactome.org/PathwayBrowser/#/R-SPO-350769 trans-Golgi Network Coat Activation IEA Schizosaccharomyces pombe 37565 R-SPO-389788 https://reactome.org/PathwayBrowser/#/R-SPO-389788 Activation of PAKs by RAC1 and CDC42 IEA Schizosaccharomyces pombe 37565 R-SPO-399998 https://reactome.org/PathwayBrowser/#/R-SPO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Schizosaccharomyces pombe 37565 R-SPO-418574 https://reactome.org/PathwayBrowser/#/R-SPO-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Schizosaccharomyces pombe 37565 R-SPO-418582 https://reactome.org/PathwayBrowser/#/R-SPO-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Schizosaccharomyces pombe 37565 R-SPO-419166 https://reactome.org/PathwayBrowser/#/R-SPO-419166 GEFs activate RhoA,B,C IEA Schizosaccharomyces pombe 37565 R-SPO-428941 https://reactome.org/PathwayBrowser/#/R-SPO-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Schizosaccharomyces pombe 37565 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 37565 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 37565 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 37565 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 37565 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 37565 R-SPO-5578744 https://reactome.org/PathwayBrowser/#/R-SPO-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Schizosaccharomyces pombe 37565 R-SPO-5623508 https://reactome.org/PathwayBrowser/#/R-SPO-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Schizosaccharomyces pombe 37565 R-SPO-5623622 https://reactome.org/PathwayBrowser/#/R-SPO-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Schizosaccharomyces pombe 37565 R-SPO-5623632 https://reactome.org/PathwayBrowser/#/R-SPO-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Schizosaccharomyces pombe 37565 R-SPO-5623667 https://reactome.org/PathwayBrowser/#/R-SPO-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Schizosaccharomyces pombe 37565 R-SPO-5626469 https://reactome.org/PathwayBrowser/#/R-SPO-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Schizosaccharomyces pombe 37565 R-SPO-5626507 https://reactome.org/PathwayBrowser/#/R-SPO-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Schizosaccharomyces pombe 37565 R-SPO-5626549 https://reactome.org/PathwayBrowser/#/R-SPO-5626549 IQGAPs bind CALM1 IEA Schizosaccharomyces pombe 37565 R-SPO-5627775 https://reactome.org/PathwayBrowser/#/R-SPO-5627775 Autophosphorylation of PAK1,2,3 IEA Schizosaccharomyces pombe 37565 R-SPO-5638014 https://reactome.org/PathwayBrowser/#/R-SPO-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Schizosaccharomyces pombe 37565 R-SPO-5653957 https://reactome.org/PathwayBrowser/#/R-SPO-5653957 Rag dimer formation IEA Schizosaccharomyces pombe 37565 R-SPO-5694409 https://reactome.org/PathwayBrowser/#/R-SPO-5694409 Nucleotide exchange on RAB1 IEA Schizosaccharomyces pombe 37565 R-SPO-5694441 https://reactome.org/PathwayBrowser/#/R-SPO-5694441 CSNK1D phosphorylates SEC23 IEA Schizosaccharomyces pombe 37565 R-SPO-5694522 https://reactome.org/PathwayBrowser/#/R-SPO-5694522 Inner coat assembly and cargo binding IEA Schizosaccharomyces pombe 37565 R-SPO-5694527 https://reactome.org/PathwayBrowser/#/R-SPO-5694527 Loss of SAR1B GTPase IEA Schizosaccharomyces pombe 37565 R-SPO-6800138 https://reactome.org/PathwayBrowser/#/R-SPO-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Schizosaccharomyces pombe 37565 R-SPO-6807864 https://reactome.org/PathwayBrowser/#/R-SPO-6807864 RAB1:GTP recruits GBF1 to the ERGIC IEA Schizosaccharomyces pombe 37565 R-SPO-6807866 https://reactome.org/PathwayBrowser/#/R-SPO-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Schizosaccharomyces pombe 37565 R-SPO-6807868 https://reactome.org/PathwayBrowser/#/R-SPO-6807868 GBF1 stimulates ARF nucleotide exchange IEA Schizosaccharomyces pombe 37565 R-SPO-6807872 https://reactome.org/PathwayBrowser/#/R-SPO-6807872 Active ARF recruits coatomer IEA Schizosaccharomyces pombe 37565 R-SPO-6807877 https://reactome.org/PathwayBrowser/#/R-SPO-6807877 ARFGAPs stimulate ARF GTPase activity IEA Schizosaccharomyces pombe 37565 R-SPO-6811411 https://reactome.org/PathwayBrowser/#/R-SPO-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Schizosaccharomyces pombe 37565 R-SPO-6811412 https://reactome.org/PathwayBrowser/#/R-SPO-6811412 Active ARF recruits coatomer to the Golgi IEA Schizosaccharomyces pombe 37565 R-SPO-6811414 https://reactome.org/PathwayBrowser/#/R-SPO-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Schizosaccharomyces pombe 37565 R-SPO-6811415 https://reactome.org/PathwayBrowser/#/R-SPO-6811415 RAB:GTP recruits GBF1 to the Golgi membrane IEA Schizosaccharomyces pombe 37565 R-SPO-6811417 https://reactome.org/PathwayBrowser/#/R-SPO-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Schizosaccharomyces pombe 37565 R-SPO-6811418 https://reactome.org/PathwayBrowser/#/R-SPO-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Schizosaccharomyces pombe 37565 R-SPO-6811427 https://reactome.org/PathwayBrowser/#/R-SPO-6811427 COPI vesicle uncoating at the ER IEA Schizosaccharomyces pombe 37565 R-SPO-6811429 https://reactome.org/PathwayBrowser/#/R-SPO-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Schizosaccharomyces pombe 37565 R-SPO-6814831 https://reactome.org/PathwayBrowser/#/R-SPO-6814831 TBC1D20 binds RAB1:GTP IEA Schizosaccharomyces pombe 37565 R-SPO-6814833 https://reactome.org/PathwayBrowser/#/R-SPO-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Schizosaccharomyces pombe 37565 R-SPO-72619 https://reactome.org/PathwayBrowser/#/R-SPO-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Schizosaccharomyces pombe 37565 R-SPO-72621 https://reactome.org/PathwayBrowser/#/R-SPO-72621 Ribosomal scanning IEA Schizosaccharomyces pombe 37565 R-SPO-72663 https://reactome.org/PathwayBrowser/#/R-SPO-72663 De novo formation of eIF2:GTP IEA Schizosaccharomyces pombe 37565 R-SPO-72669 https://reactome.org/PathwayBrowser/#/R-SPO-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Schizosaccharomyces pombe 37565 R-SPO-72671 https://reactome.org/PathwayBrowser/#/R-SPO-72671 eIF5B:GTP is hydrolyzed and released IEA Schizosaccharomyces pombe 37565 R-SPO-72672 https://reactome.org/PathwayBrowser/#/R-SPO-72672 The 60S subunit joins the translation initiation complex IEA Schizosaccharomyces pombe 37565 R-SPO-72691 https://reactome.org/PathwayBrowser/#/R-SPO-72691 Formation of the 43S pre-initiation complex IEA Schizosaccharomyces pombe 37565 R-SPO-72697 https://reactome.org/PathwayBrowser/#/R-SPO-72697 Start codon recognition IEA Schizosaccharomyces pombe 37565 R-SPO-72722 https://reactome.org/PathwayBrowser/#/R-SPO-72722 eIF2 activation IEA Schizosaccharomyces pombe 37565 R-SPO-77081 https://reactome.org/PathwayBrowser/#/R-SPO-77081 Formation of the CE:GMP intermediate complex IEA Schizosaccharomyces pombe 37565 R-SPO-8847534 https://reactome.org/PathwayBrowser/#/R-SPO-8847534 RAB43 hydrolyses GTP IEA Schizosaccharomyces pombe 37565 R-SPO-8847537 https://reactome.org/PathwayBrowser/#/R-SPO-8847537 RAB43:GTP binds USP8NL IEA Schizosaccharomyces pombe 37565 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 37565 R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 37565 R-SPO-8875318 https://reactome.org/PathwayBrowser/#/R-SPO-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Schizosaccharomyces pombe 37565 R-SPO-8875320 https://reactome.org/PathwayBrowser/#/R-SPO-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Schizosaccharomyces pombe 37565 R-SPO-8876190 https://reactome.org/PathwayBrowser/#/R-SPO-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Schizosaccharomyces pombe 37565 R-SPO-8876193 https://reactome.org/PathwayBrowser/#/R-SPO-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Schizosaccharomyces pombe 37565 R-SPO-8876454 https://reactome.org/PathwayBrowser/#/R-SPO-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Schizosaccharomyces pombe 37565 R-SPO-8877475 https://reactome.org/PathwayBrowser/#/R-SPO-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Schizosaccharomyces pombe 37565 R-SPO-8981637 https://reactome.org/PathwayBrowser/#/R-SPO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Schizosaccharomyces pombe 37565 R-SPO-8981892 https://reactome.org/PathwayBrowser/#/R-SPO-8981892 Active G alpha (z) binds RGS proteins IEA Schizosaccharomyces pombe 37565 R-SPO-8981926 https://reactome.org/PathwayBrowser/#/R-SPO-8981926 RAC1 and CDC42 activate PAK3 IEA Schizosaccharomyces pombe 37565 R-SPO-8981931 https://reactome.org/PathwayBrowser/#/R-SPO-8981931 RAC1 and CDC42 activate PAK2 IEA Schizosaccharomyces pombe 37565 R-SPO-8982017 https://reactome.org/PathwayBrowser/#/R-SPO-8982017 Active G alpha (q) binds RGS proteins IEA Schizosaccharomyces pombe 37565 R-SPO-8982019 https://reactome.org/PathwayBrowser/#/R-SPO-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Schizosaccharomyces pombe 37565 R-SPO-8982020 https://reactome.org/PathwayBrowser/#/R-SPO-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Schizosaccharomyces pombe 37565 R-SPO-8982021 https://reactome.org/PathwayBrowser/#/R-SPO-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Schizosaccharomyces pombe 37565 R-SPO-8982025 https://reactome.org/PathwayBrowser/#/R-SPO-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Schizosaccharomyces pombe 37565 R-SPO-9013006 https://reactome.org/PathwayBrowser/#/R-SPO-9013006 RHOA:GTP translocates to the ER membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9013009 https://reactome.org/PathwayBrowser/#/R-SPO-9013009 RHOA binds effectors at the plasma membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9013022 https://reactome.org/PathwayBrowser/#/R-SPO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Schizosaccharomyces pombe 37565 R-SPO-9013024 https://reactome.org/PathwayBrowser/#/R-SPO-9013024 RHOB binds effectors at the plasma membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9013110 https://reactome.org/PathwayBrowser/#/R-SPO-9013110 RHOC binds effectors at the plasma membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9013111 https://reactome.org/PathwayBrowser/#/R-SPO-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Schizosaccharomyces pombe 37565 R-SPO-9013159 https://reactome.org/PathwayBrowser/#/R-SPO-9013159 CDC42 GEFs activate CDC42 IEA Schizosaccharomyces pombe 37565 R-SPO-9013161 https://reactome.org/PathwayBrowser/#/R-SPO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Schizosaccharomyces pombe 37565 R-SPO-9013435 https://reactome.org/PathwayBrowser/#/R-SPO-9013435 RHOD auto-activates IEA Schizosaccharomyces pombe 37565 R-SPO-9013437 https://reactome.org/PathwayBrowser/#/R-SPO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Schizosaccharomyces pombe 37565 R-SPO-9013438 https://reactome.org/PathwayBrowser/#/R-SPO-9013438 RHOD binds effectors at the endosome membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9013452 https://reactome.org/PathwayBrowser/#/R-SPO-9013452 RHOD:GTP translocates to the endosome membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9017488 https://reactome.org/PathwayBrowser/#/R-SPO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Schizosaccharomyces pombe 37565 R-SPO-9018745 https://reactome.org/PathwayBrowser/#/R-SPO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Schizosaccharomyces pombe 37565 R-SPO-9018746 https://reactome.org/PathwayBrowser/#/R-SPO-9018746 RHOQ binds effectors at the plasma membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9018747 https://reactome.org/PathwayBrowser/#/R-SPO-9018747 RHOQ GEFs activate RHOQ IEA Schizosaccharomyces pombe 37565 R-SPO-9018766 https://reactome.org/PathwayBrowser/#/R-SPO-9018766 RHOU binds effectors at the plasma membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9018768 https://reactome.org/PathwayBrowser/#/R-SPO-9018768 RHOU auto-activates IEA Schizosaccharomyces pombe 37565 R-SPO-9018794 https://reactome.org/PathwayBrowser/#/R-SPO-9018794 RHOV binds effectors at the plasma membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9018798 https://reactome.org/PathwayBrowser/#/R-SPO-9018798 RHOV binds GTP IEA Schizosaccharomyces pombe 37565 R-SPO-9018814 https://reactome.org/PathwayBrowser/#/R-SPO-9018814 RHOT1 hydrolyzes GTP IEA Schizosaccharomyces pombe 37565 R-SPO-9018815 https://reactome.org/PathwayBrowser/#/R-SPO-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9018824 https://reactome.org/PathwayBrowser/#/R-SPO-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9018826 https://reactome.org/PathwayBrowser/#/R-SPO-9018826 RHOT2 hydrolyzes GTP IEA Schizosaccharomyces pombe 37565 R-SPO-9018836 https://reactome.org/PathwayBrowser/#/R-SPO-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Schizosaccharomyces pombe 37565 R-SPO-9624845 https://reactome.org/PathwayBrowser/#/R-SPO-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Schizosaccharomyces pombe 37565 R-SPO-9624876 https://reactome.org/PathwayBrowser/#/R-SPO-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Schizosaccharomyces pombe 37565 R-SPO-9624893 https://reactome.org/PathwayBrowser/#/R-SPO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Schizosaccharomyces pombe 37565 R-SPO-9639286 https://reactome.org/PathwayBrowser/#/R-SPO-9639286 RRAGC,D exchanges GTP for GDP IEA Schizosaccharomyces pombe 37565 R-SPO-9640167 https://reactome.org/PathwayBrowser/#/R-SPO-9640167 RRAGA,B exchanges GDP for GTP IEA Schizosaccharomyces pombe 37565 R-SPO-9640195 https://reactome.org/PathwayBrowser/#/R-SPO-9640195 RRAGA,B hydrolyzes GTP IEA Schizosaccharomyces pombe 37565 R-SPO-9645598 https://reactome.org/PathwayBrowser/#/R-SPO-9645598 RRAGC,D hydrolyzes GTP IEA Schizosaccharomyces pombe 37565 R-SPO-9645608 https://reactome.org/PathwayBrowser/#/R-SPO-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Schizosaccharomyces pombe 37565 R-SPO-9646468 https://reactome.org/PathwayBrowser/#/R-SPO-9646468 mTORC1 binds RHEB:GTP IEA Schizosaccharomyces pombe 37565 R-SPO-9690494 https://reactome.org/PathwayBrowser/#/R-SPO-9690494 RHOB translocates to the endosome membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9692800 https://reactome.org/PathwayBrowser/#/R-SPO-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9693111 https://reactome.org/PathwayBrowser/#/R-SPO-9693111 RHOF auto-activates IEA Schizosaccharomyces pombe 37565 R-SPO-9693198 https://reactome.org/PathwayBrowser/#/R-SPO-9693198 RHOD binds effectors at the plasma membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9693207 https://reactome.org/PathwayBrowser/#/R-SPO-9693207 RHOD translocates to the mitochondrial outer membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9693214 https://reactome.org/PathwayBrowser/#/R-SPO-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9693243 https://reactome.org/PathwayBrowser/#/R-SPO-9693243 RHOD translocates to the Golgi membrane IEA Schizosaccharomyces pombe 37565 R-SPO-9693282 https://reactome.org/PathwayBrowser/#/R-SPO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Schizosaccharomyces pombe 37565 R-SPO-9696266 https://reactome.org/PathwayBrowser/#/R-SPO-9696266 RND2 binds effectors IEA Schizosaccharomyces pombe 37565 R-SPO-9696267 https://reactome.org/PathwayBrowser/#/R-SPO-9696267 RND3 binds GTP IEA Schizosaccharomyces pombe 37565 R-SPO-9696271 https://reactome.org/PathwayBrowser/#/R-SPO-9696271 RND1 binds effectors IEA Schizosaccharomyces pombe 37565 R-SPO-9696274 https://reactome.org/PathwayBrowser/#/R-SPO-9696274 RND1 binds GTP IEA Schizosaccharomyces pombe 37565 R-SPO-9696275 https://reactome.org/PathwayBrowser/#/R-SPO-9696275 RND2 binds GTP IEA Schizosaccharomyces pombe 37565 R-SPO-9714361 https://reactome.org/PathwayBrowser/#/R-SPO-9714361 RHOC activates endoplasmic reticulum effectors IEA Schizosaccharomyces pombe 37565 R-SPO-9714363 https://reactome.org/PathwayBrowser/#/R-SPO-9714363 RHOC translocates to the endoplasmic reticulum membrane IEA Schizosaccharomyces pombe 37565 R-SSC-1008248 https://reactome.org/PathwayBrowser/#/R-SSC-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Sus scrofa 37565 R-SSC-111524 https://reactome.org/PathwayBrowser/#/R-SSC-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Sus scrofa 37565 R-SSC-111879 https://reactome.org/PathwayBrowser/#/R-SSC-111879 PIP2 hydrolysis IEA Sus scrofa 37565 R-SSC-112037 https://reactome.org/PathwayBrowser/#/R-SSC-112037 Inactivation of PLC beta IEA Sus scrofa 37565 R-SSC-112271 https://reactome.org/PathwayBrowser/#/R-SSC-112271 The receptor:G-protein complex dissociates IEA Sus scrofa 37565 R-SSC-114542 https://reactome.org/PathwayBrowser/#/R-SSC-114542 RAC1,RAC2,RHOG activate PI3K IEA Sus scrofa 37565 R-SSC-114544 https://reactome.org/PathwayBrowser/#/R-SSC-114544 p115-RhoGEF activation of RHOA IEA Sus scrofa 37565 R-SSC-114548 https://reactome.org/PathwayBrowser/#/R-SSC-114548 G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) IEA Sus scrofa 37565 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa 37565 R-SSC-114558 https://reactome.org/PathwayBrowser/#/R-SSC-114558 Thrombin-activated PARs activate Gq IEA Sus scrofa 37565 R-SSC-114688 https://reactome.org/PathwayBrowser/#/R-SSC-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Sus scrofa 37565 R-SSC-1168636 https://reactome.org/PathwayBrowser/#/R-SSC-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Sus scrofa 37565 R-SSC-1250383 https://reactome.org/PathwayBrowser/#/R-SSC-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Sus scrofa 37565 R-SSC-1306972 https://reactome.org/PathwayBrowser/#/R-SSC-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Sus scrofa 37565 R-SSC-1433415 https://reactome.org/PathwayBrowser/#/R-SSC-1433415 Activation of RAC1 IEA Sus scrofa 37565 R-SSC-1433471 https://reactome.org/PathwayBrowser/#/R-SSC-1433471 Activation of RAS by p-KIT bound SOS1 IEA Sus scrofa 37565 R-SSC-1474146 https://reactome.org/PathwayBrowser/#/R-SSC-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Sus scrofa 37565 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa 37565 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa 37565 R-SSC-156913 https://reactome.org/PathwayBrowser/#/R-SSC-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Sus scrofa 37565 R-SSC-156930 https://reactome.org/PathwayBrowser/#/R-SSC-156930 GTP-binding activates eEF2 IEA Sus scrofa 37565 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa 37565 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa 37565 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa 37565 R-SSC-165195 https://reactome.org/PathwayBrowser/#/R-SSC-165195 GTP loading by Rheb IEA Sus scrofa 37565 R-SSC-165680 https://reactome.org/PathwayBrowser/#/R-SSC-165680 Formation of active mTORC1 complex IEA Sus scrofa 37565 R-SSC-165692 https://reactome.org/PathwayBrowser/#/R-SSC-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Sus scrofa 37565 R-SSC-165718 https://reactome.org/PathwayBrowser/#/R-SSC-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Sus scrofa 37565 R-SSC-167415 https://reactome.org/PathwayBrowser/#/R-SSC-167415 G-protein alpha subunit is inactivated IEA Sus scrofa 37565 R-SSC-167429 https://reactome.org/PathwayBrowser/#/R-SSC-167429 The receptor:G-protein complex binds GTP IEA Sus scrofa 37565 R-SSC-169904 https://reactome.org/PathwayBrowser/#/R-SSC-169904 C3G stimulates nucleotide exchange on Rap1 IEA Sus scrofa 37565 R-SSC-170026 https://reactome.org/PathwayBrowser/#/R-SSC-170026 Protons are translocated from the intermembrane space to the matrix IEA Sus scrofa 37565 R-SSC-170666 https://reactome.org/PathwayBrowser/#/R-SSC-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa 37565 R-SSC-170671 https://reactome.org/PathwayBrowser/#/R-SSC-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Sus scrofa 37565 R-SSC-170672 https://reactome.org/PathwayBrowser/#/R-SSC-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Sus scrofa 37565 R-SSC-170676 https://reactome.org/PathwayBrowser/#/R-SSC-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Sus scrofa 37565 R-SSC-170685 https://reactome.org/PathwayBrowser/#/R-SSC-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa 37565 R-SSC-170686 https://reactome.org/PathwayBrowser/#/R-SSC-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Sus scrofa 37565 R-SSC-170986 https://reactome.org/PathwayBrowser/#/R-SSC-170986 Ral-GDS binds to Ras-GTP IEA Sus scrofa 37565 R-SSC-177938 https://reactome.org/PathwayBrowser/#/R-SSC-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Sus scrofa 37565 R-SSC-177945 https://reactome.org/PathwayBrowser/#/R-SSC-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Sus scrofa 37565 R-SSC-183002 https://reactome.org/PathwayBrowser/#/R-SSC-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Sus scrofa 37565 R-SSC-183084 https://reactome.org/PathwayBrowser/#/R-SSC-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Sus scrofa 37565 R-SSC-183094 https://reactome.org/PathwayBrowser/#/R-SSC-183094 CDC42:GTP binds CBL:Beta-Pix IEA Sus scrofa 37565 R-SSC-186834 https://reactome.org/PathwayBrowser/#/R-SSC-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Sus scrofa 37565 R-SSC-190520 https://reactome.org/PathwayBrowser/#/R-SSC-190520 Association of Golgi transport vesicles with microtubules IEA Sus scrofa 37565 R-SSC-194518 https://reactome.org/PathwayBrowser/#/R-SSC-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Sus scrofa 37565 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa 37565 R-SSC-2029454 https://reactome.org/PathwayBrowser/#/R-SSC-2029454 Autophosphorylation of PAK1 IEA Sus scrofa 37565 R-SSC-2029456 https://reactome.org/PathwayBrowser/#/R-SSC-2029456 RAC1 and CDC42 activate PAK1 IEA Sus scrofa 37565 R-SSC-2029465 https://reactome.org/PathwayBrowser/#/R-SSC-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Sus scrofa 37565 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa 37565 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa 37565 R-SSC-2029469 https://reactome.org/PathwayBrowser/#/R-SSC-2029469 p-ERK phosphorylates WAVEs and ABI IEA Sus scrofa 37565 R-SSC-203973 https://reactome.org/PathwayBrowser/#/R-SSC-203973 Vesicle budding IEA Sus scrofa 37565 R-SSC-203977 https://reactome.org/PathwayBrowser/#/R-SSC-203977 SAR1 Activation And Membrane Binding IEA Sus scrofa 37565 R-SSC-203979 https://reactome.org/PathwayBrowser/#/R-SSC-203979 Coat Assembly IEA Sus scrofa 37565 R-SSC-204008 https://reactome.org/PathwayBrowser/#/R-SSC-204008 SEC31:SEC13 and v-SNARE recruitment IEA Sus scrofa 37565 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa 37565 R-SSC-205136 https://reactome.org/PathwayBrowser/#/R-SSC-205136 GTP-bound RAC contributes to JNK activation IEA Sus scrofa 37565 R-SSC-2065539 https://reactome.org/PathwayBrowser/#/R-SSC-2065539 SREBP1A,1C,2:Importin beta-1 dissociates IEA Sus scrofa 37565 R-SSC-210977 https://reactome.org/PathwayBrowser/#/R-SSC-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Sus scrofa 37565 R-SSC-2130194 https://reactome.org/PathwayBrowser/#/R-SSC-2130194 ABL phosphorylates WAVEs IEA Sus scrofa 37565 R-SSC-2130619 https://reactome.org/PathwayBrowser/#/R-SSC-2130619 TGN-lysosomal vesicle coat assembly IEA Sus scrofa 37565 R-SSC-2130641 https://reactome.org/PathwayBrowser/#/R-SSC-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Sus scrofa 37565 R-SSC-2130725 https://reactome.org/PathwayBrowser/#/R-SSC-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Sus scrofa 37565 R-SSC-2130731 https://reactome.org/PathwayBrowser/#/R-SSC-2130731 Formation of COPII vesicle IEA Sus scrofa 37565 R-SSC-2179407 https://reactome.org/PathwayBrowser/#/R-SSC-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Sus scrofa 37565 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa 37565 R-SSC-2197691 https://reactome.org/PathwayBrowser/#/R-SSC-2197691 WIP binds WASP,N-WASP, activating them IEA Sus scrofa 37565 R-SSC-2213243 https://reactome.org/PathwayBrowser/#/R-SSC-2213243 Fusion of COPII vesicle with Golgi complex IEA Sus scrofa 37565 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa 37565 R-SSC-2214351 https://reactome.org/PathwayBrowser/#/R-SSC-2214351 PLK1 phosphorylates GORASP1 IEA Sus scrofa 37565 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 37565 R-SSC-2422927 https://reactome.org/PathwayBrowser/#/R-SSC-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Sus scrofa 37565 R-SSC-2424476 https://reactome.org/PathwayBrowser/#/R-SSC-2424476 Activation of RAC1 by VAV2/3 IEA Sus scrofa 37565 R-SSC-2424477 https://reactome.org/PathwayBrowser/#/R-SSC-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Sus scrofa 37565 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa 37565 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa 37565 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa 37565 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa 37565 R-SSC-2485182 https://reactome.org/PathwayBrowser/#/R-SSC-2485182 Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 IEA Sus scrofa 37565 R-SSC-2562526 https://reactome.org/PathwayBrowser/#/R-SSC-2562526 PLK1 phosphorylates OPTN IEA Sus scrofa 37565 R-SSC-2584246 https://reactome.org/PathwayBrowser/#/R-SSC-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Sus scrofa 37565 R-SSC-2730840 https://reactome.org/PathwayBrowser/#/R-SSC-2730840 Activation of RAC1 by VAV IEA Sus scrofa 37565 R-SSC-2730856 https://reactome.org/PathwayBrowser/#/R-SSC-2730856 Autophosphorylation of PAK IEA Sus scrofa 37565 R-SSC-2730889 https://reactome.org/PathwayBrowser/#/R-SSC-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Sus scrofa 37565 R-SSC-350769 https://reactome.org/PathwayBrowser/#/R-SSC-350769 trans-Golgi Network Coat Activation IEA Sus scrofa 37565 R-SSC-354060 https://reactome.org/PathwayBrowser/#/R-SSC-354060 Translocation of RIAM to plasma membrane IEA Sus scrofa 37565 R-SSC-354073 https://reactome.org/PathwayBrowser/#/R-SSC-354073 Autophosphorylation of PTK2 at Y397 IEA Sus scrofa 37565 R-SSC-354077 https://reactome.org/PathwayBrowser/#/R-SSC-354077 Integrin alphaIIb beta3 activation IEA Sus scrofa 37565 R-SSC-354087 https://reactome.org/PathwayBrowser/#/R-SSC-354087 Recruitment of GRB2 to p-PTK2 IEA Sus scrofa 37565 R-SSC-354097 https://reactome.org/PathwayBrowser/#/R-SSC-354097 Activation of Talin IEA Sus scrofa 37565 R-SSC-354124 https://reactome.org/PathwayBrowser/#/R-SSC-354124 Phosphorylation of pPTK2 by SRC IEA Sus scrofa 37565 R-SSC-354149 https://reactome.org/PathwayBrowser/#/R-SSC-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Sus scrofa 37565 R-SSC-354165 https://reactome.org/PathwayBrowser/#/R-SSC-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Sus scrofa 37565 R-SSC-354173 https://reactome.org/PathwayBrowser/#/R-SSC-354173 Activation of Rap1 by cytosolic GEFs IEA Sus scrofa 37565 R-SSC-372693 https://reactome.org/PathwayBrowser/#/R-SSC-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Sus scrofa 37565 R-SSC-372697 https://reactome.org/PathwayBrowser/#/R-SSC-372697 Crk binding to p130cas IEA Sus scrofa 37565 R-SSC-372705 https://reactome.org/PathwayBrowser/#/R-SSC-372705 Recruitment of BCAR1 to PTK2 complex IEA Sus scrofa 37565 R-SSC-372819 https://reactome.org/PathwayBrowser/#/R-SSC-372819 PCK2 phosphorylates OA to yield PEP IEA Sus scrofa 37565 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa 37565 R-SSC-377640 https://reactome.org/PathwayBrowser/#/R-SSC-377640 Autophosphorylation of SRC IEA Sus scrofa 37565 R-SSC-377641 https://reactome.org/PathwayBrowser/#/R-SSC-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Sus scrofa 37565 R-SSC-377643 https://reactome.org/PathwayBrowser/#/R-SSC-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Sus scrofa 37565 R-SSC-377644 https://reactome.org/PathwayBrowser/#/R-SSC-377644 Release of CSK from SRC IEA Sus scrofa 37565 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 37565 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 37565 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 37565 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa 37565 R-SSC-380979 https://reactome.org/PathwayBrowser/#/R-SSC-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Sus scrofa 37565 R-SSC-381727 https://reactome.org/PathwayBrowser/#/R-SSC-381727 RAP1A exchanges GDP for GTP IEA Sus scrofa 37565 R-SSC-3858475 https://reactome.org/PathwayBrowser/#/R-SSC-3858475 ppDVL recruits RAC IEA Sus scrofa 37565 R-SSC-3858495 https://reactome.org/PathwayBrowser/#/R-SSC-3858495 DAAM1 recruits GTP-bound RHOA IEA Sus scrofa 37565 R-SSC-389348 https://reactome.org/PathwayBrowser/#/R-SSC-389348 Activation of Rac1 by pVav1 IEA Sus scrofa 37565 R-SSC-389350 https://reactome.org/PathwayBrowser/#/R-SSC-389350 Activation of Cdc42 by pVav1 IEA Sus scrofa 37565 R-SSC-389788 https://reactome.org/PathwayBrowser/#/R-SSC-389788 Activation of PAKs by RAC1 and CDC42 IEA Sus scrofa 37565 R-SSC-392054 https://reactome.org/PathwayBrowser/#/R-SSC-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Sus scrofa 37565 R-SSC-392064 https://reactome.org/PathwayBrowser/#/R-SSC-392064 G alpha (z) inhibits adenylate cyclase IEA Sus scrofa 37565 R-SSC-392195 https://reactome.org/PathwayBrowser/#/R-SSC-392195 Gi activation by P2Y purinoceptor 12 IEA Sus scrofa 37565 R-SSC-392202 https://reactome.org/PathwayBrowser/#/R-SSC-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Sus scrofa 37565 R-SSC-392513 https://reactome.org/PathwayBrowser/#/R-SSC-392513 Rap1 signal termination by Rap1GAPs IEA Sus scrofa 37565 R-SSC-3928576 https://reactome.org/PathwayBrowser/#/R-SSC-3928576 RHOA:GTP binds ROCK, activating it IEA Sus scrofa 37565 R-SSC-3928592 https://reactome.org/PathwayBrowser/#/R-SSC-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Sus scrofa 37565 R-SSC-3928595 https://reactome.org/PathwayBrowser/#/R-SSC-3928595 N-WASP binds ARP2/3 and G-actin IEA Sus scrofa 37565 R-SSC-3928601 https://reactome.org/PathwayBrowser/#/R-SSC-3928601 CDC42 and PIP2 bind WASL, activating it IEA Sus scrofa 37565 R-SSC-3928619 https://reactome.org/PathwayBrowser/#/R-SSC-3928619 PAK1 binds RAC1:GTP IEA Sus scrofa 37565 R-SSC-3928620 https://reactome.org/PathwayBrowser/#/R-SSC-3928620 PAK1 autophosphorylates IEA Sus scrofa 37565 R-SSC-3928625 https://reactome.org/PathwayBrowser/#/R-SSC-3928625 PAKs autophosphorylate IEA Sus scrofa 37565 R-SSC-3928628 https://reactome.org/PathwayBrowser/#/R-SSC-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa 37565 R-SSC-3928633 https://reactome.org/PathwayBrowser/#/R-SSC-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Sus scrofa 37565 R-SSC-3928640 https://reactome.org/PathwayBrowser/#/R-SSC-3928640 PAKs phosphorylate MLC IEA Sus scrofa 37565 R-SSC-3928641 https://reactome.org/PathwayBrowser/#/R-SSC-3928641 PAK binds RAC and bPIX IEA Sus scrofa 37565 R-SSC-3928642 https://reactome.org/PathwayBrowser/#/R-SSC-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa 37565 R-SSC-3928647 https://reactome.org/PathwayBrowser/#/R-SSC-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Sus scrofa 37565 R-SSC-3928651 https://reactome.org/PathwayBrowser/#/R-SSC-3928651 NGEF exchanges GTP for GDP on RHOA IEA Sus scrofa 37565 R-SSC-392870 https://reactome.org/PathwayBrowser/#/R-SSC-392870 Gs activation by prostacyclin receptor IEA Sus scrofa 37565 R-SSC-3965444 https://reactome.org/PathwayBrowser/#/R-SSC-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Sus scrofa 37565 R-SSC-3965447 https://reactome.org/PathwayBrowser/#/R-SSC-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Sus scrofa 37565 R-SSC-397835 https://reactome.org/PathwayBrowser/#/R-SSC-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Sus scrofa 37565 R-SSC-397891 https://reactome.org/PathwayBrowser/#/R-SSC-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Sus scrofa 37565 R-SSC-398184 https://reactome.org/PathwayBrowser/#/R-SSC-398184 LARG activation by G alpha 12/13 IEA Sus scrofa 37565 R-SSC-398185 https://reactome.org/PathwayBrowser/#/R-SSC-398185 LARG binds plexin B1 IEA Sus scrofa 37565 R-SSC-399930 https://reactome.org/PathwayBrowser/#/R-SSC-399930 Activation of PAK by Rac1 IEA Sus scrofa 37565 R-SSC-399939 https://reactome.org/PathwayBrowser/#/R-SSC-399939 Autophosphorylation of PAK IEA Sus scrofa 37565 R-SSC-399952 https://reactome.org/PathwayBrowser/#/R-SSC-399952 Phosphorylation of LIMK-1 by PAK IEA Sus scrofa 37565 R-SSC-399998 https://reactome.org/PathwayBrowser/#/R-SSC-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Sus scrofa 37565 R-SSC-400037 https://reactome.org/PathwayBrowser/#/R-SSC-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Sus scrofa 37565 R-SSC-400092 https://reactome.org/PathwayBrowser/#/R-SSC-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Sus scrofa 37565 R-SSC-400586 https://reactome.org/PathwayBrowser/#/R-SSC-400586 G alpha (q) binds to Trio family RhoGEFs IEA Sus scrofa 37565 R-SSC-400677 https://reactome.org/PathwayBrowser/#/R-SSC-400677 Rnd1 interacts with Plexin-B1:Sema4D IEA Sus scrofa 37565 R-SSC-400682 https://reactome.org/PathwayBrowser/#/R-SSC-400682 Active Rac1 interacts with Plexin-B1:Sema4D IEA Sus scrofa 37565 R-SSC-4086392 https://reactome.org/PathwayBrowser/#/R-SSC-4086392 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 37565 R-SSC-4093331 https://reactome.org/PathwayBrowser/#/R-SSC-4093331 Ras:GTP binds p120-RasGAP IEA Sus scrofa 37565 R-SSC-4093336 https://reactome.org/PathwayBrowser/#/R-SSC-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa 37565 R-SSC-4093339 https://reactome.org/PathwayBrowser/#/R-SSC-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Sus scrofa 37565 R-SSC-416358 https://reactome.org/PathwayBrowser/#/R-SSC-416358 G alpha (q) inhibits PI3K alpha IEA Sus scrofa 37565 R-SSC-416516 https://reactome.org/PathwayBrowser/#/R-SSC-416516 GRK2 sequesters activated Gq IEA Sus scrofa 37565 R-SSC-416546 https://reactome.org/PathwayBrowser/#/R-SSC-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Sus scrofa 37565 R-SSC-416559 https://reactome.org/PathwayBrowser/#/R-SSC-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Sus scrofa 37565 R-SSC-416562 https://reactome.org/PathwayBrowser/#/R-SSC-416562 p190RhoGAP binds Plexin-B1 IEA Sus scrofa 37565 R-SSC-416588 https://reactome.org/PathwayBrowser/#/R-SSC-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Sus scrofa 37565 R-SSC-418574 https://reactome.org/PathwayBrowser/#/R-SSC-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa 37565 R-SSC-418576 https://reactome.org/PathwayBrowser/#/R-SSC-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Sus scrofa 37565 R-SSC-418582 https://reactome.org/PathwayBrowser/#/R-SSC-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa 37565 R-SSC-419049 https://reactome.org/PathwayBrowser/#/R-SSC-419049 ROCK activation by RHO IEA Sus scrofa 37565 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa 37565 R-SSC-420883 https://reactome.org/PathwayBrowser/#/R-SSC-420883 Opsins act as GEFs for G alpha-t IEA Sus scrofa 37565 R-SSC-421831 https://reactome.org/PathwayBrowser/#/R-SSC-421831 trans-Golgi Network Coat Assembly IEA Sus scrofa 37565 R-SSC-421835 https://reactome.org/PathwayBrowser/#/R-SSC-421835 trans-Golgi Network Vesicle Scission IEA Sus scrofa 37565 R-SSC-428750 https://reactome.org/PathwayBrowser/#/R-SSC-428750 Gq activation by TP receptor IEA Sus scrofa 37565 R-SSC-428752 https://reactome.org/PathwayBrowser/#/R-SSC-428752 Dissociation of the TP:Gq complex IEA Sus scrofa 37565 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa 37565 R-SSC-428918 https://reactome.org/PathwayBrowser/#/R-SSC-428918 Dissociation of the TP:G13 complex IEA Sus scrofa 37565 R-SSC-428941 https://reactome.org/PathwayBrowser/#/R-SSC-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Sus scrofa 37565 R-SSC-429415 https://reactome.org/PathwayBrowser/#/R-SSC-429415 SYK binds to integrin alphaIIb beta3 IEA Sus scrofa 37565 R-SSC-429441 https://reactome.org/PathwayBrowser/#/R-SSC-429441 SYK activation by SRC IEA Sus scrofa 37565 R-SSC-432096 https://reactome.org/PathwayBrowser/#/R-SSC-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Sus scrofa 37565 R-SSC-432195 https://reactome.org/PathwayBrowser/#/R-SSC-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Sus scrofa 37565 R-SSC-432706 https://reactome.org/PathwayBrowser/#/R-SSC-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Sus scrofa 37565 R-SSC-432707 https://reactome.org/PathwayBrowser/#/R-SSC-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Sus scrofa 37565 R-SSC-442273 https://reactome.org/PathwayBrowser/#/R-SSC-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Sus scrofa 37565 R-SSC-442291 https://reactome.org/PathwayBrowser/#/R-SSC-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Sus scrofa 37565 R-SSC-443905 https://reactome.org/PathwayBrowser/#/R-SSC-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Sus scrofa 37565 R-SSC-443910 https://reactome.org/PathwayBrowser/#/R-SSC-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Sus scrofa 37565 R-SSC-445064 https://reactome.org/PathwayBrowser/#/R-SSC-445064 Activation of Rac1 by VAV2 IEA Sus scrofa 37565 R-SSC-445072 https://reactome.org/PathwayBrowser/#/R-SSC-445072 Interaction of PAK1 with Rac1-GTP IEA Sus scrofa 37565 R-SSC-447074 https://reactome.org/PathwayBrowser/#/R-SSC-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Sus scrofa 37565 R-SSC-448958 https://reactome.org/PathwayBrowser/#/R-SSC-448958 Nuclear translocation of p38 MAPK IEA Sus scrofa 37565 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 37565 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 37565 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 37565 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 37565 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 37565 R-SSC-5218804 https://reactome.org/PathwayBrowser/#/R-SSC-5218804 p38 MAPK activation by VEGFR IEA Sus scrofa 37565 R-SSC-5218812 https://reactome.org/PathwayBrowser/#/R-SSC-5218812 FYN phosphorylates PAK2 IEA Sus scrofa 37565 R-SSC-5218814 https://reactome.org/PathwayBrowser/#/R-SSC-5218814 PAK2 autophorylates IEA Sus scrofa 37565 R-SSC-5218826 https://reactome.org/PathwayBrowser/#/R-SSC-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Sus scrofa 37565 R-SSC-5218827 https://reactome.org/PathwayBrowser/#/R-SSC-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Sus scrofa 37565 R-SSC-5218832 https://reactome.org/PathwayBrowser/#/R-SSC-5218832 CDC42:GTP binds PAK2 IEA Sus scrofa 37565 R-SSC-5218839 https://reactome.org/PathwayBrowser/#/R-SSC-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Sus scrofa 37565 R-SSC-5218841 https://reactome.org/PathwayBrowser/#/R-SSC-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Sus scrofa 37565 R-SSC-5218845 https://reactome.org/PathwayBrowser/#/R-SSC-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Sus scrofa 37565 R-SSC-5218850 https://reactome.org/PathwayBrowser/#/R-SSC-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa 37565 R-SSC-5228992 https://reactome.org/PathwayBrowser/#/R-SSC-5228992 ROCK1,ROCK2 are activated IEA Sus scrofa 37565 R-SSC-5250209 https://reactome.org/PathwayBrowser/#/R-SSC-5250209 ARL2:GTP:ARL2BP binds SLC25A4 IEA Sus scrofa 37565 R-SSC-5250210 https://reactome.org/PathwayBrowser/#/R-SSC-5250210 ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix IEA Sus scrofa 37565 R-SSC-5250217 https://reactome.org/PathwayBrowser/#/R-SSC-5250217 ARL2:GTP binds ARL2BP IEA Sus scrofa 37565 R-SSC-5357445 https://reactome.org/PathwayBrowser/#/R-SSC-5357445 PAK1-3 dimer disassociates IEA Sus scrofa 37565 R-SSC-5357472 https://reactome.org/PathwayBrowser/#/R-SSC-5357472 PAK1-3 autophosphorylates IEA Sus scrofa 37565 R-SSC-5357483 https://reactome.org/PathwayBrowser/#/R-SSC-5357483 RAC1 binds PAK1-3 IEA Sus scrofa 37565 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa 37565 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa 37565 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Sus scrofa 37565 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa 37565 R-SSC-555065 https://reactome.org/PathwayBrowser/#/R-SSC-555065 Formation of clathrin coated vesicle IEA Sus scrofa 37565 R-SSC-5578744 https://reactome.org/PathwayBrowser/#/R-SSC-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Sus scrofa 37565 R-SSC-5610733 https://reactome.org/PathwayBrowser/#/R-SSC-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Sus scrofa 37565 R-SSC-5610767 https://reactome.org/PathwayBrowser/#/R-SSC-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Sus scrofa 37565 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa 37565 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 37565 R-SSC-5618328 https://reactome.org/PathwayBrowser/#/R-SSC-5618328 ATAT acetylates microtubules IEA Sus scrofa 37565 R-SSC-5618331 https://reactome.org/PathwayBrowser/#/R-SSC-5618331 HDAC6 deacetylates microtubules IEA Sus scrofa 37565 R-SSC-5620914 https://reactome.org/PathwayBrowser/#/R-SSC-5620914 ARF4:GTP binds VxPx-motifs of membrane proteins IEA Sus scrofa 37565 R-SSC-5620921 https://reactome.org/PathwayBrowser/#/R-SSC-5620921 ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex IEA Sus scrofa 37565 R-SSC-5623508 https://reactome.org/PathwayBrowser/#/R-SSC-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Sus scrofa 37565 R-SSC-5623513 https://reactome.org/PathwayBrowser/#/R-SSC-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Sus scrofa 37565 R-SSC-5623519 https://reactome.org/PathwayBrowser/#/R-SSC-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Sus scrofa 37565 R-SSC-5623521 https://reactome.org/PathwayBrowser/#/R-SSC-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa 37565 R-SSC-5623524 https://reactome.org/PathwayBrowser/#/R-SSC-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Sus scrofa 37565 R-SSC-5623525 https://reactome.org/PathwayBrowser/#/R-SSC-5623525 Cargo-carrying vesicles bud from the TGN IEA Sus scrofa 37565 R-SSC-5623527 https://reactome.org/PathwayBrowser/#/R-SSC-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Sus scrofa 37565 R-SSC-5623622 https://reactome.org/PathwayBrowser/#/R-SSC-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Sus scrofa 37565 R-SSC-5623632 https://reactome.org/PathwayBrowser/#/R-SSC-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Sus scrofa 37565 R-SSC-5623667 https://reactome.org/PathwayBrowser/#/R-SSC-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Sus scrofa 37565 R-SSC-5624126 https://reactome.org/PathwayBrowser/#/R-SSC-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Sus scrofa 37565 R-SSC-5624127 https://reactome.org/PathwayBrowser/#/R-SSC-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Sus scrofa 37565 R-SSC-5625959 https://reactome.org/PathwayBrowser/#/R-SSC-5625959 Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) IEA Sus scrofa 37565 R-SSC-5626469 https://reactome.org/PathwayBrowser/#/R-SSC-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Sus scrofa 37565 R-SSC-5626507 https://reactome.org/PathwayBrowser/#/R-SSC-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Sus scrofa 37565 R-SSC-5626549 https://reactome.org/PathwayBrowser/#/R-SSC-5626549 IQGAPs bind CALM1 IEA Sus scrofa 37565 R-SSC-5627071 https://reactome.org/PathwayBrowser/#/R-SSC-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane IEA Sus scrofa 37565 R-SSC-5627072 https://reactome.org/PathwayBrowser/#/R-SSC-5627072 RHOQ binds GOPC:CFTR IEA Sus scrofa 37565 R-SSC-5627775 https://reactome.org/PathwayBrowser/#/R-SSC-5627775 Autophosphorylation of PAK1,2,3 IEA Sus scrofa 37565 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa 37565 R-SSC-5638014 https://reactome.org/PathwayBrowser/#/R-SSC-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Sus scrofa 37565 R-SSC-5653957 https://reactome.org/PathwayBrowser/#/R-SSC-5653957 Rag dimer formation IEA Sus scrofa 37565 R-SSC-5653968 https://reactome.org/PathwayBrowser/#/R-SSC-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Sus scrofa 37565 R-SSC-5653974 https://reactome.org/PathwayBrowser/#/R-SSC-5653974 Ragulator binds Rag dimers IEA Sus scrofa 37565 R-SSC-5654392 https://reactome.org/PathwayBrowser/#/R-SSC-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-5654402 https://reactome.org/PathwayBrowser/#/R-SSC-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-5654413 https://reactome.org/PathwayBrowser/#/R-SSC-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-5654426 https://reactome.org/PathwayBrowser/#/R-SSC-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-5654600 https://reactome.org/PathwayBrowser/#/R-SSC-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-5654618 https://reactome.org/PathwayBrowser/#/R-SSC-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-5654647 https://reactome.org/PathwayBrowser/#/R-SSC-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-5654663 https://reactome.org/PathwayBrowser/#/R-SSC-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-5658231 https://reactome.org/PathwayBrowser/#/R-SSC-5658231 RAS GAPs stimulate RAS GTPase activity IEA Sus scrofa 37565 R-SSC-5658435 https://reactome.org/PathwayBrowser/#/R-SSC-5658435 RAS GAPs bind RAS:GTP IEA Sus scrofa 37565 R-SSC-5665727 https://reactome.org/PathwayBrowser/#/R-SSC-5665727 FMNL2 binds CDC42:GTP IEA Sus scrofa 37565 R-SSC-5665748 https://reactome.org/PathwayBrowser/#/R-SSC-5665748 FMNL2 binds RHOC:GTP IEA Sus scrofa 37565 R-SSC-5665751 https://reactome.org/PathwayBrowser/#/R-SSC-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin IEA Sus scrofa 37565 R-SSC-5665761 https://reactome.org/PathwayBrowser/#/R-SSC-5665761 FMNL3 binds RHOC:GTP IEA Sus scrofa 37565 R-SSC-5665767 https://reactome.org/PathwayBrowser/#/R-SSC-5665767 Activated FMNL3 binds G-actin IEA Sus scrofa 37565 R-SSC-5665802 https://reactome.org/PathwayBrowser/#/R-SSC-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Sus scrofa 37565 R-SSC-5665809 https://reactome.org/PathwayBrowser/#/R-SSC-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Sus scrofa 37565 R-SSC-5665982 https://reactome.org/PathwayBrowser/#/R-SSC-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 IEA Sus scrofa 37565 R-SSC-5665989 https://reactome.org/PathwayBrowser/#/R-SSC-5665989 DIAPH1 binds RHOA:GTP IEA Sus scrofa 37565 R-SSC-5666070 https://reactome.org/PathwayBrowser/#/R-SSC-5666070 RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes IEA Sus scrofa 37565 R-SSC-5666088 https://reactome.org/PathwayBrowser/#/R-SSC-5666088 RHOD:GTP recruits DAIPH2-3 to endosomes IEA Sus scrofa 37565 R-SSC-5666104 https://reactome.org/PathwayBrowser/#/R-SSC-5666104 RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes IEA Sus scrofa 37565 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa 37565 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa 37565 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa 37565 R-SSC-5666197 https://reactome.org/PathwayBrowser/#/R-SSC-5666197 RHOA:GTP:RTKN binds LIN7B IEA Sus scrofa 37565 R-SSC-5666216 https://reactome.org/PathwayBrowser/#/R-SSC-5666216 RHOA:GTP:RTKN binds TAX1BP3 IEA Sus scrofa 37565 R-SSC-5667008 https://reactome.org/PathwayBrowser/#/R-SSC-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Sus scrofa 37565 R-SSC-5668605 https://reactome.org/PathwayBrowser/#/R-SSC-5668605 RAC2:GTP binds NOX2 complex IEA Sus scrofa 37565 R-SSC-5668629 https://reactome.org/PathwayBrowser/#/R-SSC-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Sus scrofa 37565 R-SSC-5668714 https://reactome.org/PathwayBrowser/#/R-SSC-5668714 RAC1:GTP binds NOX1 complex IEA Sus scrofa 37565 R-SSC-5668718 https://reactome.org/PathwayBrowser/#/R-SSC-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 37565 R-SSC-5668731 https://reactome.org/PathwayBrowser/#/R-SSC-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 37565 R-SSC-5668735 https://reactome.org/PathwayBrowser/#/R-SSC-5668735 RAC1:GTP binds NOX3 complex IEA Sus scrofa 37565 R-SSC-5671993 https://reactome.org/PathwayBrowser/#/R-SSC-5671993 CIT-3 binds DLG4 IEA Sus scrofa 37565 R-SSC-5672010 https://reactome.org/PathwayBrowser/#/R-SSC-5672010 Active MTORC1 phosphorylates ULK1 IEA Sus scrofa 37565 R-SSC-5672017 https://reactome.org/PathwayBrowser/#/R-SSC-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Sus scrofa 37565 R-SSC-5672027 https://reactome.org/PathwayBrowser/#/R-SSC-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Sus scrofa 37565 R-SSC-5672083 https://reactome.org/PathwayBrowser/#/R-SSC-5672083 KTN1 binds Kinesin-1 IEA Sus scrofa 37565 R-SSC-5672304 https://reactome.org/PathwayBrowser/#/R-SSC-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 IEA Sus scrofa 37565 R-SSC-5672329 https://reactome.org/PathwayBrowser/#/R-SSC-5672329 IQGAP1 binds CLIP1 and microtubules IEA Sus scrofa 37565 R-SSC-5672817 https://reactome.org/PathwayBrowser/#/R-SSC-5672817 Active MTORC1 binds the ULK1 complex IEA Sus scrofa 37565 R-SSC-5672824 https://reactome.org/PathwayBrowser/#/R-SSC-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Sus scrofa 37565 R-SSC-5672828 https://reactome.org/PathwayBrowser/#/R-SSC-5672828 mTORC1 phosphorylates AKT1S1 IEA Sus scrofa 37565 R-SSC-5672843 https://reactome.org/PathwayBrowser/#/R-SSC-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Sus scrofa 37565 R-SSC-5672950 https://reactome.org/PathwayBrowser/#/R-SSC-5672950 "Activator" RAF:YWHAB dimer binds RAS:GTP IEA Sus scrofa 37565 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-5672966 https://reactome.org/PathwayBrowser/#/R-SSC-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Sus scrofa 37565 R-SSC-5672969 https://reactome.org/PathwayBrowser/#/R-SSC-5672969 Phosphorylation of RAF IEA Sus scrofa 37565 R-SSC-5672972 https://reactome.org/PathwayBrowser/#/R-SSC-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Sus scrofa 37565 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 37565 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 37565 R-SSC-5672980 https://reactome.org/PathwayBrowser/#/R-SSC-5672980 Dissociation of RAS:RAF complex IEA Sus scrofa 37565 R-SSC-5673768 https://reactome.org/PathwayBrowser/#/R-SSC-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Sus scrofa 37565 R-SSC-5674018 https://reactome.org/PathwayBrowser/#/R-SSC-5674018 BRAP binds RAS:GTP IEA Sus scrofa 37565 R-SSC-5674022 https://reactome.org/PathwayBrowser/#/R-SSC-5674022 BRAP autoubiquitinates IEA Sus scrofa 37565 R-SSC-5675417 https://reactome.org/PathwayBrowser/#/R-SSC-5675417 PEBP1 binds activated RAF1 IEA Sus scrofa 37565 R-SSC-5675431 https://reactome.org/PathwayBrowser/#/R-SSC-5675431 PP2A dephosphorylates RAF1 IEA Sus scrofa 37565 R-SSC-5675433 https://reactome.org/PathwayBrowser/#/R-SSC-5675433 PP5 dephosphorylates RAF1 S338 IEA Sus scrofa 37565 R-SSC-5675790 https://reactome.org/PathwayBrowser/#/R-SSC-5675790 MTORC1 dissociates from ULK complex IEA Sus scrofa 37565 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa 37565 R-SSC-5694417 https://reactome.org/PathwayBrowser/#/R-SSC-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Sus scrofa 37565 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa 37565 R-SSC-5694522 https://reactome.org/PathwayBrowser/#/R-SSC-5694522 Inner coat assembly and cargo binding IEA Sus scrofa 37565 R-SSC-5694527 https://reactome.org/PathwayBrowser/#/R-SSC-5694527 Loss of SAR1B GTPase IEA Sus scrofa 37565 R-SSC-5696197 https://reactome.org/PathwayBrowser/#/R-SSC-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Sus scrofa 37565 R-SSC-6785648 https://reactome.org/PathwayBrowser/#/R-SSC-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Sus scrofa 37565 R-SSC-6787533 https://reactome.org/PathwayBrowser/#/R-SSC-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Sus scrofa 37565 R-SSC-6788611 https://reactome.org/PathwayBrowser/#/R-SSC-6788611 HYKK phosphorylates 5HLYS IEA Sus scrofa 37565 R-SSC-6789092 https://reactome.org/PathwayBrowser/#/R-SSC-6789092 NOX2 generates superoxide anion from oxygen IEA Sus scrofa 37565 R-SSC-6800138 https://reactome.org/PathwayBrowser/#/R-SSC-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Sus scrofa 37565 R-SSC-6807868 https://reactome.org/PathwayBrowser/#/R-SSC-6807868 GBF1 stimulates ARF nucleotide exchange IEA Sus scrofa 37565 R-SSC-6807872 https://reactome.org/PathwayBrowser/#/R-SSC-6807872 Active ARF recruits coatomer IEA Sus scrofa 37565 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa 37565 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa 37565 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa 37565 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa 37565 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa 37565 R-SSC-6811417 https://reactome.org/PathwayBrowser/#/R-SSC-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Sus scrofa 37565 R-SSC-6811418 https://reactome.org/PathwayBrowser/#/R-SSC-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Sus scrofa 37565 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa 37565 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa 37565 R-SSC-6814086 https://reactome.org/PathwayBrowser/#/R-SSC-6814086 ARFRP1 recruits ARL1 to the TGN IEA Sus scrofa 37565 R-SSC-6814088 https://reactome.org/PathwayBrowser/#/R-SSC-6814088 SYS1 binds AcM-ARFRP1 IEA Sus scrofa 37565 R-SSC-6814091 https://reactome.org/PathwayBrowser/#/R-SSC-6814091 ARL1 recruits TGN Golgin homodimers IEA Sus scrofa 37565 R-SSC-6814094 https://reactome.org/PathwayBrowser/#/R-SSC-6814094 ARL1:GTP binds ARFIP2 IEA Sus scrofa 37565 R-SSC-6814096 https://reactome.org/PathwayBrowser/#/R-SSC-6814096 ARL1:GTP binds SCOC IEA Sus scrofa 37565 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa 37565 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa 37565 R-SSC-6814671 https://reactome.org/PathwayBrowser/#/R-SSC-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Sus scrofa 37565 R-SSC-70241 https://reactome.org/PathwayBrowser/#/R-SSC-70241 PCK1 phosphorylates OA to yield PEP IEA Sus scrofa 37565 R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Sus scrofa 37565 R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Sus scrofa 37565 R-SSC-71775 https://reactome.org/PathwayBrowser/#/R-SSC-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Sus scrofa 37565 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa 37565 R-SSC-72663 https://reactome.org/PathwayBrowser/#/R-SSC-72663 De novo formation of eIF2:GTP IEA Sus scrofa 37565 R-SSC-72669 https://reactome.org/PathwayBrowser/#/R-SSC-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Sus scrofa 37565 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa 37565 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa 37565 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa 37565 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa 37565 R-SSC-72722 https://reactome.org/PathwayBrowser/#/R-SSC-72722 eIF2 activation IEA Sus scrofa 37565 R-SSC-74059 https://reactome.org/PathwayBrowser/#/R-SSC-74059 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 37565 R-SSC-74885 https://reactome.org/PathwayBrowser/#/R-SSC-74885 GUCYs converts GTP to cGMP IEA Sus scrofa 37565 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 37565 R-SSC-749453 https://reactome.org/PathwayBrowser/#/R-SSC-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Sus scrofa 37565 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 37565 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa 37565 R-SSC-751024 https://reactome.org/PathwayBrowser/#/R-SSC-751024 The Ligand:GPCR:Gz complex dissociates IEA Sus scrofa 37565 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa 37565 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa 37565 R-SSC-8847534 https://reactome.org/PathwayBrowser/#/R-SSC-8847534 RAB43 hydrolyses GTP IEA Sus scrofa 37565 R-SSC-8847537 https://reactome.org/PathwayBrowser/#/R-SSC-8847537 RAB43:GTP binds USP8NL IEA Sus scrofa 37565 R-SSC-8847887 https://reactome.org/PathwayBrowser/#/R-SSC-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Sus scrofa 37565 R-SSC-8848618 https://reactome.org/PathwayBrowser/#/R-SSC-8848618 Activation of RAC1 by the PXN:CRK complex IEA Sus scrofa 37565 R-SSC-8849082 https://reactome.org/PathwayBrowser/#/R-SSC-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Sus scrofa 37565 R-SSC-8849085 https://reactome.org/PathwayBrowser/#/R-SSC-8849085 ARHGAP35 binds RHOA:GTP IEA Sus scrofa 37565 R-SSC-8849748 https://reactome.org/PathwayBrowser/#/R-SSC-8849748 The COG complex binds RABs at the Golgi membrane IEA Sus scrofa 37565 R-SSC-8850041 https://reactome.org/PathwayBrowser/#/R-SSC-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Sus scrofa 37565 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 37565 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 37565 R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 37565 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 37565 R-SSC-8851827 https://reactome.org/PathwayBrowser/#/R-SSC-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Sus scrofa 37565 R-SSC-8851877 https://reactome.org/PathwayBrowser/#/R-SSC-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Sus scrofa 37565 R-SSC-8851899 https://reactome.org/PathwayBrowser/#/R-SSC-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Sus scrofa 37565 R-SSC-8852280 https://reactome.org/PathwayBrowser/#/R-SSC-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Sus scrofa 37565 R-SSC-8852298 https://reactome.org/PathwayBrowser/#/R-SSC-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Sus scrofa 37565 R-SSC-8852306 https://reactome.org/PathwayBrowser/#/R-SSC-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Sus scrofa 37565 R-SSC-8854173 https://reactome.org/PathwayBrowser/#/R-SSC-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Sus scrofa 37565 R-SSC-8854182 https://reactome.org/PathwayBrowser/#/R-SSC-8854182 TBC1D17 binds OPTN:RAB8A IEA Sus scrofa 37565 R-SSC-8854293 https://reactome.org/PathwayBrowser/#/R-SSC-8854293 TBC1D10A (EPI64) binds ARF6:GTP IEA Sus scrofa 37565 R-SSC-8854612 https://reactome.org/PathwayBrowser/#/R-SSC-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Sus scrofa 37565 R-SSC-8856808 https://reactome.org/PathwayBrowser/#/R-SSC-8856808 Recruitment of AP-2 complex and clathrin IEA Sus scrofa 37565 R-SSC-8865774 https://reactome.org/PathwayBrowser/#/R-SSC-8865774 TTLLs polyglutamylate tubulin IEA Sus scrofa 37565 R-SSC-8867370 https://reactome.org/PathwayBrowser/#/R-SSC-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Sus scrofa 37565 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa 37565 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 37565 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa 37565 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 37565 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 37565 R-SSC-8875318 https://reactome.org/PathwayBrowser/#/R-SSC-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Sus scrofa 37565 R-SSC-8875320 https://reactome.org/PathwayBrowser/#/R-SSC-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Sus scrofa 37565 R-SSC-8875568 https://reactome.org/PathwayBrowser/#/R-SSC-8875568 RAPGEF1 activates RAP1 IEA Sus scrofa 37565 R-SSC-8875591 https://reactome.org/PathwayBrowser/#/R-SSC-8875591 DOCK7 activates RAC1 IEA Sus scrofa 37565 R-SSC-8875659 https://reactome.org/PathwayBrowser/#/R-SSC-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Sus scrofa 37565 R-SSC-8875661 https://reactome.org/PathwayBrowser/#/R-SSC-8875661 GGA3 associates with activated MET receptor IEA Sus scrofa 37565 R-SSC-8876188 https://reactome.org/PathwayBrowser/#/R-SSC-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Sus scrofa 37565 R-SSC-8876190 https://reactome.org/PathwayBrowser/#/R-SSC-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Sus scrofa 37565 R-SSC-8876191 https://reactome.org/PathwayBrowser/#/R-SSC-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Sus scrofa 37565 R-SSC-8876454 https://reactome.org/PathwayBrowser/#/R-SSC-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Sus scrofa 37565 R-SSC-8876615 https://reactome.org/PathwayBrowser/#/R-SSC-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Sus scrofa 37565 R-SSC-8877308 https://reactome.org/PathwayBrowser/#/R-SSC-8877308 MADD exchanges GTP for GDP on RAB27 IEA Sus scrofa 37565 R-SSC-8877311 https://reactome.org/PathwayBrowser/#/R-SSC-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Sus scrofa 37565 R-SSC-8877451 https://reactome.org/PathwayBrowser/#/R-SSC-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Sus scrofa 37565 R-SSC-8877612 https://reactome.org/PathwayBrowser/#/R-SSC-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Sus scrofa 37565 R-SSC-8877760 https://reactome.org/PathwayBrowser/#/R-SSC-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Sus scrofa 37565 R-SSC-8877813 https://reactome.org/PathwayBrowser/#/R-SSC-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Sus scrofa 37565 R-SSC-8877998 https://reactome.org/PathwayBrowser/#/R-SSC-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Sus scrofa 37565 R-SSC-8941613 https://reactome.org/PathwayBrowser/#/R-SSC-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-8941618 https://reactome.org/PathwayBrowser/#/R-SSC-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-8941623 https://reactome.org/PathwayBrowser/#/R-SSC-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-8941628 https://reactome.org/PathwayBrowser/#/R-SSC-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa 37565 R-SSC-8944454 https://reactome.org/PathwayBrowser/#/R-SSC-8944454 mTORC1 phosphorylates MAF1 IEA Sus scrofa 37565 R-SSC-8944457 https://reactome.org/PathwayBrowser/#/R-SSC-8944457 MAF1 translocates to the nucleus IEA Sus scrofa 37565 R-SSC-8951490 https://reactome.org/PathwayBrowser/#/R-SSC-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Sus scrofa 37565 R-SSC-8951498 https://reactome.org/PathwayBrowser/#/R-SSC-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Sus scrofa 37565 R-SSC-8952716 https://reactome.org/PathwayBrowser/#/R-SSC-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Sus scrofa 37565 R-SSC-8952726 https://reactome.org/PathwayBrowser/#/R-SSC-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Sus scrofa 37565 R-SSC-8964242 https://reactome.org/PathwayBrowser/#/R-SSC-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Sus scrofa 37565 R-SSC-8964246 https://reactome.org/PathwayBrowser/#/R-SSC-8964246 BTK in G alpha (12)-BTK complex is activated IEA Sus scrofa 37565 R-SSC-8964274 https://reactome.org/PathwayBrowser/#/R-SSC-8964274 G alpha (12) binds BTK IEA Sus scrofa 37565 R-SSC-8964280 https://reactome.org/PathwayBrowser/#/R-SSC-8964280 Active Gq binds BTK IEA Sus scrofa 37565 R-SSC-8964284 https://reactome.org/PathwayBrowser/#/R-SSC-8964284 BTK in active Gq-BTK complex is activated IEA Sus scrofa 37565 R-SSC-8964329 https://reactome.org/PathwayBrowser/#/R-SSC-8964329 G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC IEA Sus scrofa 37565 R-SSC-8964333 https://reactome.org/PathwayBrowser/#/R-SSC-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) IEA Sus scrofa 37565 R-SSC-8964340 https://reactome.org/PathwayBrowser/#/R-SSC-8964340 Gq-BTK complex dissociates to Active BTK and Gq IEA Sus scrofa 37565 R-SSC-8964599 https://reactome.org/PathwayBrowser/#/R-SSC-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Sus scrofa 37565 R-SSC-8964604 https://reactome.org/PathwayBrowser/#/R-SSC-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Sus scrofa 37565 R-SSC-8964614 https://reactome.org/PathwayBrowser/#/R-SSC-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Sus scrofa 37565 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa 37565 R-SSC-8981353 https://reactome.org/PathwayBrowser/#/R-SSC-8981353 RASA1 stimulates RAS GTPase activity IEA Sus scrofa 37565 R-SSC-8981355 https://reactome.org/PathwayBrowser/#/R-SSC-8981355 RASA1 binds RAS:GTP IEA Sus scrofa 37565 R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa 37565 R-SSC-8981892 https://reactome.org/PathwayBrowser/#/R-SSC-8981892 Active G alpha (z) binds RGS proteins IEA Sus scrofa 37565 R-SSC-8981931 https://reactome.org/PathwayBrowser/#/R-SSC-8981931 RAC1 and CDC42 activate PAK2 IEA Sus scrofa 37565 R-SSC-8982017 https://reactome.org/PathwayBrowser/#/R-SSC-8982017 Active G alpha (q) binds RGS proteins IEA Sus scrofa 37565 R-SSC-8982019 https://reactome.org/PathwayBrowser/#/R-SSC-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Sus scrofa 37565 R-SSC-8982020 https://reactome.org/PathwayBrowser/#/R-SSC-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Sus scrofa 37565 R-SSC-8982021 https://reactome.org/PathwayBrowser/#/R-SSC-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Sus scrofa 37565 R-SSC-8982025 https://reactome.org/PathwayBrowser/#/R-SSC-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Sus scrofa 37565 R-SSC-8982640 https://reactome.org/PathwayBrowser/#/R-SSC-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Sus scrofa 37565 R-SSC-8985594 https://reactome.org/PathwayBrowser/#/R-SSC-8985594 MYO9B inactivates RHOA IEA Sus scrofa 37565 R-SSC-9013004 https://reactome.org/PathwayBrowser/#/R-SSC-9013004 RHOA binds effectors at the ER membrane IEA Sus scrofa 37565 R-SSC-9013006 https://reactome.org/PathwayBrowser/#/R-SSC-9013006 RHOA:GTP translocates to the ER membrane IEA Sus scrofa 37565 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9013022 https://reactome.org/PathwayBrowser/#/R-SSC-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Sus scrofa 37565 R-SSC-9013023 https://reactome.org/PathwayBrowser/#/R-SSC-9013023 RHOB GEFs activate RHOB IEA Sus scrofa 37565 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9013109 https://reactome.org/PathwayBrowser/#/R-SSC-9013109 RHOC GEFs activate RHOC IEA Sus scrofa 37565 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9013111 https://reactome.org/PathwayBrowser/#/R-SSC-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Sus scrofa 37565 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa 37565 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa 37565 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa 37565 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa 37565 R-SSC-9013435 https://reactome.org/PathwayBrowser/#/R-SSC-9013435 RHOD auto-activates IEA Sus scrofa 37565 R-SSC-9013437 https://reactome.org/PathwayBrowser/#/R-SSC-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Sus scrofa 37565 R-SSC-9013438 https://reactome.org/PathwayBrowser/#/R-SSC-9013438 RHOD binds effectors at the endosome membrane IEA Sus scrofa 37565 R-SSC-9013452 https://reactome.org/PathwayBrowser/#/R-SSC-9013452 RHOD:GTP translocates to the endosome membrane IEA Sus scrofa 37565 R-SSC-9014294 https://reactome.org/PathwayBrowser/#/R-SSC-9014294 RAC2 binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9014295 https://reactome.org/PathwayBrowser/#/R-SSC-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Sus scrofa 37565 R-SSC-9014296 https://reactome.org/PathwayBrowser/#/R-SSC-9014296 RAC2 GEFs activate RAC2 IEA Sus scrofa 37565 R-SSC-9014420 https://reactome.org/PathwayBrowser/#/R-SSC-9014420 RAC2 translocates to the phagocytic vesicle membrane IEA Sus scrofa 37565 R-SSC-9014424 https://reactome.org/PathwayBrowser/#/R-SSC-9014424 RAC2 binds effectors at the phagocytic vesicle membrane IEA Sus scrofa 37565 R-SSC-9014433 https://reactome.org/PathwayBrowser/#/R-SSC-9014433 RHOG GEFs activate RHOG IEA Sus scrofa 37565 R-SSC-9014434 https://reactome.org/PathwayBrowser/#/R-SSC-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Sus scrofa 37565 R-SSC-9014449 https://reactome.org/PathwayBrowser/#/R-SSC-9014449 RHOG binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9014454 https://reactome.org/PathwayBrowser/#/R-SSC-9014454 RHOG translocates to the ER membrane IEA Sus scrofa 37565 R-SSC-9014467 https://reactome.org/PathwayBrowser/#/R-SSC-9014467 RHOG binds effectors at the ER membrane IEA Sus scrofa 37565 R-SSC-9017488 https://reactome.org/PathwayBrowser/#/R-SSC-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Sus scrofa 37565 R-SSC-9017491 https://reactome.org/PathwayBrowser/#/R-SSC-9017491 RHOJ GEFs activate RHOJ IEA Sus scrofa 37565 R-SSC-9018745 https://reactome.org/PathwayBrowser/#/R-SSC-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Sus scrofa 37565 R-SSC-9018746 https://reactome.org/PathwayBrowser/#/R-SSC-9018746 RHOQ binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9018747 https://reactome.org/PathwayBrowser/#/R-SSC-9018747 RHOQ GEFs activate RHOQ IEA Sus scrofa 37565 R-SSC-9018754 https://reactome.org/PathwayBrowser/#/R-SSC-9018754 GDIs bind RHOH IEA Sus scrofa 37565 R-SSC-9018756 https://reactome.org/PathwayBrowser/#/R-SSC-9018756 RHOH binds GTP IEA Sus scrofa 37565 R-SSC-9018758 https://reactome.org/PathwayBrowser/#/R-SSC-9018758 RHOH binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9018766 https://reactome.org/PathwayBrowser/#/R-SSC-9018766 RHOU binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9018768 https://reactome.org/PathwayBrowser/#/R-SSC-9018768 RHOU auto-activates IEA Sus scrofa 37565 R-SSC-9018774 https://reactome.org/PathwayBrowser/#/R-SSC-9018774 RHOBTB1 binds GTP IEA Sus scrofa 37565 R-SSC-9018778 https://reactome.org/PathwayBrowser/#/R-SSC-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Sus scrofa 37565 R-SSC-9018785 https://reactome.org/PathwayBrowser/#/R-SSC-9018785 RHOBTB2 binds GTP IEA Sus scrofa 37565 R-SSC-9018787 https://reactome.org/PathwayBrowser/#/R-SSC-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Sus scrofa 37565 R-SSC-9018794 https://reactome.org/PathwayBrowser/#/R-SSC-9018794 RHOV binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9018798 https://reactome.org/PathwayBrowser/#/R-SSC-9018798 RHOV binds GTP IEA Sus scrofa 37565 R-SSC-9018804 https://reactome.org/PathwayBrowser/#/R-SSC-9018804 RAC3 GEFs activate RAC3 IEA Sus scrofa 37565 R-SSC-9018806 https://reactome.org/PathwayBrowser/#/R-SSC-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Sus scrofa 37565 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9018814 https://reactome.org/PathwayBrowser/#/R-SSC-9018814 RHOT1 hydrolyzes GTP IEA Sus scrofa 37565 R-SSC-9018815 https://reactome.org/PathwayBrowser/#/R-SSC-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Sus scrofa 37565 R-SSC-9018824 https://reactome.org/PathwayBrowser/#/R-SSC-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Sus scrofa 37565 R-SSC-9018826 https://reactome.org/PathwayBrowser/#/R-SSC-9018826 RHOT2 hydrolyzes GTP IEA Sus scrofa 37565 R-SSC-9018836 https://reactome.org/PathwayBrowser/#/R-SSC-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Sus scrofa 37565 R-SSC-9032798 https://reactome.org/PathwayBrowser/#/R-SSC-9032798 DOCK3 activates RAC1 IEA Sus scrofa 37565 R-SSC-9036301 https://reactome.org/PathwayBrowser/#/R-SSC-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Sus scrofa 37565 R-SSC-939265 https://reactome.org/PathwayBrowser/#/R-SSC-939265 Activation of Rap1 by membrane-associated GEFs IEA Sus scrofa 37565 R-SSC-947535 https://reactome.org/PathwayBrowser/#/R-SSC-947535 Cyclisation of GTP to precursor Z IEA Sus scrofa 37565 R-SSC-9607304 https://reactome.org/PathwayBrowser/#/R-SSC-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Sus scrofa 37565 R-SSC-9610152 https://reactome.org/PathwayBrowser/#/R-SSC-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Sus scrofa 37565 R-SSC-9610153 https://reactome.org/PathwayBrowser/#/R-SSC-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Sus scrofa 37565 R-SSC-9610154 https://reactome.org/PathwayBrowser/#/R-SSC-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Sus scrofa 37565 R-SSC-9610156 https://reactome.org/PathwayBrowser/#/R-SSC-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Sus scrofa 37565 R-SSC-9610163 https://reactome.org/PathwayBrowser/#/R-SSC-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Sus scrofa 37565 R-SSC-9624845 https://reactome.org/PathwayBrowser/#/R-SSC-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Sus scrofa 37565 R-SSC-9624876 https://reactome.org/PathwayBrowser/#/R-SSC-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Sus scrofa 37565 R-SSC-9624893 https://reactome.org/PathwayBrowser/#/R-SSC-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Sus scrofa 37565 R-SSC-9626848 https://reactome.org/PathwayBrowser/#/R-SSC-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Sus scrofa 37565 R-SSC-9632910 https://reactome.org/PathwayBrowser/#/R-SSC-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Sus scrofa 37565 R-SSC-9632918 https://reactome.org/PathwayBrowser/#/R-SSC-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Sus scrofa 37565 R-SSC-9639286 https://reactome.org/PathwayBrowser/#/R-SSC-9639286 RRAGC,D exchanges GTP for GDP IEA Sus scrofa 37565 R-SSC-9640167 https://reactome.org/PathwayBrowser/#/R-SSC-9640167 RRAGA,B exchanges GDP for GTP IEA Sus scrofa 37565 R-SSC-9640168 https://reactome.org/PathwayBrowser/#/R-SSC-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Sus scrofa 37565 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa 37565 R-SSC-9645598 https://reactome.org/PathwayBrowser/#/R-SSC-9645598 RRAGC,D hydrolyzes GTP IEA Sus scrofa 37565 R-SSC-9645608 https://reactome.org/PathwayBrowser/#/R-SSC-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Sus scrofa 37565 R-SSC-9646468 https://reactome.org/PathwayBrowser/#/R-SSC-9646468 mTORC1 binds RHEB:GTP IEA Sus scrofa 37565 R-SSC-9646679 https://reactome.org/PathwayBrowser/#/R-SSC-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Sus scrofa 37565 R-SSC-9646685 https://reactome.org/PathwayBrowser/#/R-SSC-9646685 Aggresome dissociates from dynein and microtubule IEA Sus scrofa 37565 R-SSC-9648017 https://reactome.org/PathwayBrowser/#/R-SSC-9648017 EML4 binds to microtubules IEA Sus scrofa 37565 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa 37565 R-SSC-9649735 https://reactome.org/PathwayBrowser/#/R-SSC-9649735 Intrinsic nucleotide exchange on RAS IEA Sus scrofa 37565 R-SSC-9649736 https://reactome.org/PathwayBrowser/#/R-SSC-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Sus scrofa 37565 R-SSC-9653108 https://reactome.org/PathwayBrowser/#/R-SSC-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Sus scrofa 37565 R-SSC-9654523 https://reactome.org/PathwayBrowser/#/R-SSC-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Sus scrofa 37565 R-SSC-9654533 https://reactome.org/PathwayBrowser/#/R-SSC-9654533 KRAS4B recycles to the plasma membrane IEA Sus scrofa 37565 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa 37565 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa 37565 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 37565 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa 37565 R-SSC-9658253 https://reactome.org/PathwayBrowser/#/R-SSC-9658253 RAS:GTP binds PI3K IEA Sus scrofa 37565 R-SSC-9658445 https://reactome.org/PathwayBrowser/#/R-SSC-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Sus scrofa 37565 R-SSC-9660557 https://reactome.org/PathwayBrowser/#/R-SSC-9660557 RAS:GTP binds RAL GDS proteins IEA Sus scrofa 37565 R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa 37565 R-SSC-9690493 https://reactome.org/PathwayBrowser/#/R-SSC-9690493 RHOB binds effectors on endosomes IEA Sus scrofa 37565 R-SSC-9690494 https://reactome.org/PathwayBrowser/#/R-SSC-9690494 RHOB translocates to the endosome membrane IEA Sus scrofa 37565 R-SSC-9691168 https://reactome.org/PathwayBrowser/#/R-SSC-9691168 RAC1 translocates to the endoplasmic reticulum membrane IEA Sus scrofa 37565 R-SSC-9691174 https://reactome.org/PathwayBrowser/#/R-SSC-9691174 RAC1 binds effectors at the ER membrane IEA Sus scrofa 37565 R-SSC-9692800 https://reactome.org/PathwayBrowser/#/R-SSC-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Sus scrofa 37565 R-SSC-9692809 https://reactome.org/PathwayBrowser/#/R-SSC-9692809 CDC42 binds effectors at the ER membrane IEA Sus scrofa 37565 R-SSC-9693111 https://reactome.org/PathwayBrowser/#/R-SSC-9693111 RHOF auto-activates IEA Sus scrofa 37565 R-SSC-9693125 https://reactome.org/PathwayBrowser/#/R-SSC-9693125 RHOF binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9693198 https://reactome.org/PathwayBrowser/#/R-SSC-9693198 RHOD binds effectors at the plasma membrane IEA Sus scrofa 37565 R-SSC-9693207 https://reactome.org/PathwayBrowser/#/R-SSC-9693207 RHOD translocates to the mitochondrial outer membrane IEA Sus scrofa 37565 R-SSC-9693214 https://reactome.org/PathwayBrowser/#/R-SSC-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Sus scrofa 37565 R-SSC-9693243 https://reactome.org/PathwayBrowser/#/R-SSC-9693243 RHOD translocates to the Golgi membrane IEA Sus scrofa 37565 R-SSC-9693250 https://reactome.org/PathwayBrowser/#/R-SSC-9693250 RHOD binds effectors at the Golgi membrane IEA Sus scrofa 37565 R-SSC-9693282 https://reactome.org/PathwayBrowser/#/R-SSC-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Sus scrofa 37565 R-SSC-9696266 https://reactome.org/PathwayBrowser/#/R-SSC-9696266 RND2 binds effectors IEA Sus scrofa 37565 R-SSC-9696267 https://reactome.org/PathwayBrowser/#/R-SSC-9696267 RND3 binds GTP IEA Sus scrofa 37565 R-SSC-9696268 https://reactome.org/PathwayBrowser/#/R-SSC-9696268 RND3 binds effectors IEA Sus scrofa 37565 R-SSC-9696271 https://reactome.org/PathwayBrowser/#/R-SSC-9696271 RND1 binds effectors IEA Sus scrofa 37565 R-SSC-9696274 https://reactome.org/PathwayBrowser/#/R-SSC-9696274 RND1 binds GTP IEA Sus scrofa 37565 R-SSC-9696275 https://reactome.org/PathwayBrowser/#/R-SSC-9696275 RND2 binds GTP IEA Sus scrofa 37565 R-SSC-9714361 https://reactome.org/PathwayBrowser/#/R-SSC-9714361 RHOC activates endoplasmic reticulum effectors IEA Sus scrofa 37565 R-SSC-9714363 https://reactome.org/PathwayBrowser/#/R-SSC-9714363 RHOC translocates to the endoplasmic reticulum membrane IEA Sus scrofa 37565 R-SSC-9714477 https://reactome.org/PathwayBrowser/#/R-SSC-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Sus scrofa 37565 R-SSC-9714480 https://reactome.org/PathwayBrowser/#/R-SSC-9714480 RAC2 translocates to the mitochondrial membrane IEA Sus scrofa 37565 R-SSC-9714481 https://reactome.org/PathwayBrowser/#/R-SSC-9714481 RAC2 binds effectors at the ER membrane IEA Sus scrofa 37565 R-SSC-9714483 https://reactome.org/PathwayBrowser/#/R-SSC-9714483 RAC2 translocates to the ER membrane IEA Sus scrofa 37565 R-SSC-9714691 https://reactome.org/PathwayBrowser/#/R-SSC-9714691 RAC3 binds ER effectors IEA Sus scrofa 37565 R-SSC-9714694 https://reactome.org/PathwayBrowser/#/R-SSC-9714694 RAC3 translocates to the endoplasmic reticulum membrane IEA Sus scrofa 37565 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa 37565 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa 37565 R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa 37565 R-SSC-983424 https://reactome.org/PathwayBrowser/#/R-SSC-983424 Budding of COPII coated vesicle IEA Sus scrofa 37565 R-SSC-983425 https://reactome.org/PathwayBrowser/#/R-SSC-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Sus scrofa 37565 R-SSC-9836404 https://reactome.org/PathwayBrowser/#/R-SSC-9836404 p-PKR dimer phosphorylates MAPT IEA Sus scrofa 37565 R-XTR-111524 https://reactome.org/PathwayBrowser/#/R-XTR-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Xenopus tropicalis 37565 R-XTR-111879 https://reactome.org/PathwayBrowser/#/R-XTR-111879 PIP2 hydrolysis IEA Xenopus tropicalis 37565 R-XTR-112037 https://reactome.org/PathwayBrowser/#/R-XTR-112037 Inactivation of PLC beta IEA Xenopus tropicalis 37565 R-XTR-112271 https://reactome.org/PathwayBrowser/#/R-XTR-112271 The receptor:G-protein complex dissociates IEA Xenopus tropicalis 37565 R-XTR-114542 https://reactome.org/PathwayBrowser/#/R-XTR-114542 RAC1,RAC2,RHOG activate PI3K IEA Xenopus tropicalis 37565 R-XTR-114552 https://reactome.org/PathwayBrowser/#/R-XTR-114552 Thrombin-activated PARs activate G12/13 IEA Xenopus tropicalis 37565 R-XTR-114558 https://reactome.org/PathwayBrowser/#/R-XTR-114558 Thrombin-activated PARs activate Gq IEA Xenopus tropicalis 37565 R-XTR-114688 https://reactome.org/PathwayBrowser/#/R-XTR-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Xenopus tropicalis 37565 R-XTR-1168636 https://reactome.org/PathwayBrowser/#/R-XTR-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Xenopus tropicalis 37565 R-XTR-1250383 https://reactome.org/PathwayBrowser/#/R-XTR-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Xenopus tropicalis 37565 R-XTR-1306972 https://reactome.org/PathwayBrowser/#/R-XTR-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Xenopus tropicalis 37565 R-XTR-1433415 https://reactome.org/PathwayBrowser/#/R-XTR-1433415 Activation of RAC1 IEA Xenopus tropicalis 37565 R-XTR-1433471 https://reactome.org/PathwayBrowser/#/R-XTR-1433471 Activation of RAS by p-KIT bound SOS1 IEA Xenopus tropicalis 37565 R-XTR-1474146 https://reactome.org/PathwayBrowser/#/R-XTR-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Xenopus tropicalis 37565 R-XTR-156823 https://reactome.org/PathwayBrowser/#/R-XTR-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Xenopus tropicalis 37565 R-XTR-156930 https://reactome.org/PathwayBrowser/#/R-XTR-156930 GTP-binding activates eEF2 IEA Xenopus tropicalis 37565 R-XTR-1638803 https://reactome.org/PathwayBrowser/#/R-XTR-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Xenopus tropicalis 37565 R-XTR-1638821 https://reactome.org/PathwayBrowser/#/R-XTR-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Xenopus tropicalis 37565 R-XTR-165195 https://reactome.org/PathwayBrowser/#/R-XTR-165195 GTP loading by Rheb IEA Xenopus tropicalis 37565 R-XTR-165680 https://reactome.org/PathwayBrowser/#/R-XTR-165680 Formation of active mTORC1 complex IEA Xenopus tropicalis 37565 R-XTR-167415 https://reactome.org/PathwayBrowser/#/R-XTR-167415 G-protein alpha subunit is inactivated IEA Xenopus tropicalis 37565 R-XTR-167429 https://reactome.org/PathwayBrowser/#/R-XTR-167429 The receptor:G-protein complex binds GTP IEA Xenopus tropicalis 37565 R-XTR-169904 https://reactome.org/PathwayBrowser/#/R-XTR-169904 C3G stimulates nucleotide exchange on Rap1 IEA Xenopus tropicalis 37565 R-XTR-170026 https://reactome.org/PathwayBrowser/#/R-XTR-170026 Protons are translocated from the intermembrane space to the matrix IEA Xenopus tropicalis 37565 R-XTR-170666 https://reactome.org/PathwayBrowser/#/R-XTR-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Xenopus tropicalis 37565 R-XTR-170671 https://reactome.org/PathwayBrowser/#/R-XTR-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Xenopus tropicalis 37565 R-XTR-170672 https://reactome.org/PathwayBrowser/#/R-XTR-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Xenopus tropicalis 37565 R-XTR-170676 https://reactome.org/PathwayBrowser/#/R-XTR-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Xenopus tropicalis 37565 R-XTR-170685 https://reactome.org/PathwayBrowser/#/R-XTR-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Xenopus tropicalis 37565 R-XTR-170686 https://reactome.org/PathwayBrowser/#/R-XTR-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Xenopus tropicalis 37565 R-XTR-170986 https://reactome.org/PathwayBrowser/#/R-XTR-170986 Ral-GDS binds to Ras-GTP IEA Xenopus tropicalis 37565 R-XTR-177938 https://reactome.org/PathwayBrowser/#/R-XTR-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Xenopus tropicalis 37565 R-XTR-177945 https://reactome.org/PathwayBrowser/#/R-XTR-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Xenopus tropicalis 37565 R-XTR-183084 https://reactome.org/PathwayBrowser/#/R-XTR-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Xenopus tropicalis 37565 R-XTR-186834 https://reactome.org/PathwayBrowser/#/R-XTR-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Xenopus tropicalis 37565 R-XTR-190520 https://reactome.org/PathwayBrowser/#/R-XTR-190520 Association of Golgi transport vesicles with microtubules IEA Xenopus tropicalis 37565 R-XTR-2029454 https://reactome.org/PathwayBrowser/#/R-XTR-2029454 Autophosphorylation of PAK1 IEA Xenopus tropicalis 37565 R-XTR-2029456 https://reactome.org/PathwayBrowser/#/R-XTR-2029456 RAC1 and CDC42 activate PAK1 IEA Xenopus tropicalis 37565 R-XTR-2029466 https://reactome.org/PathwayBrowser/#/R-XTR-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Xenopus tropicalis 37565 R-XTR-2029469 https://reactome.org/PathwayBrowser/#/R-XTR-2029469 p-ERK phosphorylates WAVEs and ABI IEA Xenopus tropicalis 37565 R-XTR-203977 https://reactome.org/PathwayBrowser/#/R-XTR-203977 SAR1 Activation And Membrane Binding IEA Xenopus tropicalis 37565 R-XTR-203979 https://reactome.org/PathwayBrowser/#/R-XTR-203979 Coat Assembly IEA Xenopus tropicalis 37565 R-XTR-205039 https://reactome.org/PathwayBrowser/#/R-XTR-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Xenopus tropicalis 37565 R-XTR-2065539 https://reactome.org/PathwayBrowser/#/R-XTR-2065539 SREBP1A,1C,2:Importin beta-1 dissociates IEA Xenopus tropicalis 37565 R-XTR-210977 https://reactome.org/PathwayBrowser/#/R-XTR-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Xenopus tropicalis 37565 R-XTR-2130194 https://reactome.org/PathwayBrowser/#/R-XTR-2130194 ABL phosphorylates WAVEs IEA Xenopus tropicalis 37565 R-XTR-2130641 https://reactome.org/PathwayBrowser/#/R-XTR-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Xenopus tropicalis 37565 R-XTR-2179407 https://reactome.org/PathwayBrowser/#/R-XTR-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Xenopus tropicalis 37565 R-XTR-2197690 https://reactome.org/PathwayBrowser/#/R-XTR-2197690 Detachment of WASP/WAVE IEA Xenopus tropicalis 37565 R-XTR-2214351 https://reactome.org/PathwayBrowser/#/R-XTR-2214351 PLK1 phosphorylates GORASP1 IEA Xenopus tropicalis 37565 R-XTR-2316434 https://reactome.org/PathwayBrowser/#/R-XTR-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 37565 R-XTR-2422927 https://reactome.org/PathwayBrowser/#/R-XTR-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Xenopus tropicalis 37565 R-XTR-2424476 https://reactome.org/PathwayBrowser/#/R-XTR-2424476 Activation of RAC1 by VAV2/3 IEA Xenopus tropicalis 37565 R-XTR-2424477 https://reactome.org/PathwayBrowser/#/R-XTR-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Xenopus tropicalis 37565 R-XTR-2467809 https://reactome.org/PathwayBrowser/#/R-XTR-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Xenopus tropicalis 37565 R-XTR-2468287 https://reactome.org/PathwayBrowser/#/R-XTR-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Xenopus tropicalis 37565 R-XTR-2484822 https://reactome.org/PathwayBrowser/#/R-XTR-2484822 Kinetochore assembly IEA Xenopus tropicalis 37565 R-XTR-2485182 https://reactome.org/PathwayBrowser/#/R-XTR-2485182 Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 IEA Xenopus tropicalis 37565 R-XTR-2562526 https://reactome.org/PathwayBrowser/#/R-XTR-2562526 PLK1 phosphorylates OPTN IEA Xenopus tropicalis 37565 R-XTR-2584246 https://reactome.org/PathwayBrowser/#/R-XTR-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Xenopus tropicalis 37565 R-XTR-2730840 https://reactome.org/PathwayBrowser/#/R-XTR-2730840 Activation of RAC1 by VAV IEA Xenopus tropicalis 37565 R-XTR-2730856 https://reactome.org/PathwayBrowser/#/R-XTR-2730856 Autophosphorylation of PAK IEA Xenopus tropicalis 37565 R-XTR-2730889 https://reactome.org/PathwayBrowser/#/R-XTR-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Xenopus tropicalis 37565 R-XTR-354060 https://reactome.org/PathwayBrowser/#/R-XTR-354060 Translocation of RIAM to plasma membrane IEA Xenopus tropicalis 37565 R-XTR-354077 https://reactome.org/PathwayBrowser/#/R-XTR-354077 Integrin alphaIIb beta3 activation IEA Xenopus tropicalis 37565 R-XTR-354097 https://reactome.org/PathwayBrowser/#/R-XTR-354097 Activation of Talin IEA Xenopus tropicalis 37565 R-XTR-354173 https://reactome.org/PathwayBrowser/#/R-XTR-354173 Activation of Rap1 by cytosolic GEFs IEA Xenopus tropicalis 37565 R-XTR-375302 https://reactome.org/PathwayBrowser/#/R-XTR-375302 Kinetochore capture of astral microtubules IEA Xenopus tropicalis 37565 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 37565 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 37565 R-XTR-380316 https://reactome.org/PathwayBrowser/#/R-XTR-380316 Association of NuMA with microtubules IEA Xenopus tropicalis 37565 R-XTR-380979 https://reactome.org/PathwayBrowser/#/R-XTR-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Xenopus tropicalis 37565 R-XTR-381727 https://reactome.org/PathwayBrowser/#/R-XTR-381727 RAP1A exchanges GDP for GTP IEA Xenopus tropicalis 37565 R-XTR-3858475 https://reactome.org/PathwayBrowser/#/R-XTR-3858475 ppDVL recruits RAC IEA Xenopus tropicalis 37565 R-XTR-3858495 https://reactome.org/PathwayBrowser/#/R-XTR-3858495 DAAM1 recruits GTP-bound RHOA IEA Xenopus tropicalis 37565 R-XTR-389348 https://reactome.org/PathwayBrowser/#/R-XTR-389348 Activation of Rac1 by pVav1 IEA Xenopus tropicalis 37565 R-XTR-389350 https://reactome.org/PathwayBrowser/#/R-XTR-389350 Activation of Cdc42 by pVav1 IEA Xenopus tropicalis 37565 R-XTR-389788 https://reactome.org/PathwayBrowser/#/R-XTR-389788 Activation of PAKs by RAC1 and CDC42 IEA Xenopus tropicalis 37565 R-XTR-392054 https://reactome.org/PathwayBrowser/#/R-XTR-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Xenopus tropicalis 37565 R-XTR-392064 https://reactome.org/PathwayBrowser/#/R-XTR-392064 G alpha (z) inhibits adenylate cyclase IEA Xenopus tropicalis 37565 R-XTR-392195 https://reactome.org/PathwayBrowser/#/R-XTR-392195 Gi activation by P2Y purinoceptor 12 IEA Xenopus tropicalis 37565 R-XTR-392202 https://reactome.org/PathwayBrowser/#/R-XTR-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Xenopus tropicalis 37565 R-XTR-392513 https://reactome.org/PathwayBrowser/#/R-XTR-392513 Rap1 signal termination by Rap1GAPs IEA Xenopus tropicalis 37565 R-XTR-392835 https://reactome.org/PathwayBrowser/#/R-XTR-392835 Rap1 sequesters Raf1 to inhibit ERK cascade IEA Xenopus tropicalis 37565 R-XTR-3928576 https://reactome.org/PathwayBrowser/#/R-XTR-3928576 RHOA:GTP binds ROCK, activating it IEA Xenopus tropicalis 37565 R-XTR-3928592 https://reactome.org/PathwayBrowser/#/R-XTR-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Xenopus tropicalis 37565 R-XTR-3928619 https://reactome.org/PathwayBrowser/#/R-XTR-3928619 PAK1 binds RAC1:GTP IEA Xenopus tropicalis 37565 R-XTR-3928620 https://reactome.org/PathwayBrowser/#/R-XTR-3928620 PAK1 autophosphorylates IEA Xenopus tropicalis 37565 R-XTR-3928625 https://reactome.org/PathwayBrowser/#/R-XTR-3928625 PAKs autophosphorylate IEA Xenopus tropicalis 37565 R-XTR-3928628 https://reactome.org/PathwayBrowser/#/R-XTR-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Xenopus tropicalis 37565 R-XTR-3928633 https://reactome.org/PathwayBrowser/#/R-XTR-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Xenopus tropicalis 37565 R-XTR-3928640 https://reactome.org/PathwayBrowser/#/R-XTR-3928640 PAKs phosphorylate MLC IEA Xenopus tropicalis 37565 R-XTR-3928641 https://reactome.org/PathwayBrowser/#/R-XTR-3928641 PAK binds RAC and bPIX IEA Xenopus tropicalis 37565 R-XTR-3928642 https://reactome.org/PathwayBrowser/#/R-XTR-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Xenopus tropicalis 37565 R-XTR-3928647 https://reactome.org/PathwayBrowser/#/R-XTR-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Xenopus tropicalis 37565 R-XTR-3928651 https://reactome.org/PathwayBrowser/#/R-XTR-3928651 NGEF exchanges GTP for GDP on RHOA IEA Xenopus tropicalis 37565 R-XTR-392870 https://reactome.org/PathwayBrowser/#/R-XTR-392870 Gs activation by prostacyclin receptor IEA Xenopus tropicalis 37565 R-XTR-3965444 https://reactome.org/PathwayBrowser/#/R-XTR-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-3965447 https://reactome.org/PathwayBrowser/#/R-XTR-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Xenopus tropicalis 37565 R-XTR-397835 https://reactome.org/PathwayBrowser/#/R-XTR-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Xenopus tropicalis 37565 R-XTR-397891 https://reactome.org/PathwayBrowser/#/R-XTR-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Xenopus tropicalis 37565 R-XTR-398184 https://reactome.org/PathwayBrowser/#/R-XTR-398184 LARG activation by G alpha 12/13 IEA Xenopus tropicalis 37565 R-XTR-398185 https://reactome.org/PathwayBrowser/#/R-XTR-398185 LARG binds plexin B1 IEA Xenopus tropicalis 37565 R-XTR-399930 https://reactome.org/PathwayBrowser/#/R-XTR-399930 Activation of PAK by Rac1 IEA Xenopus tropicalis 37565 R-XTR-399939 https://reactome.org/PathwayBrowser/#/R-XTR-399939 Autophosphorylation of PAK IEA Xenopus tropicalis 37565 R-XTR-399952 https://reactome.org/PathwayBrowser/#/R-XTR-399952 Phosphorylation of LIMK-1 by PAK IEA Xenopus tropicalis 37565 R-XTR-400037 https://reactome.org/PathwayBrowser/#/R-XTR-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Xenopus tropicalis 37565 R-XTR-400092 https://reactome.org/PathwayBrowser/#/R-XTR-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Xenopus tropicalis 37565 R-XTR-400586 https://reactome.org/PathwayBrowser/#/R-XTR-400586 G alpha (q) binds to Trio family RhoGEFs IEA Xenopus tropicalis 37565 R-XTR-400677 https://reactome.org/PathwayBrowser/#/R-XTR-400677 Rnd1 interacts with Plexin-B1:Sema4D IEA Xenopus tropicalis 37565 R-XTR-400682 https://reactome.org/PathwayBrowser/#/R-XTR-400682 Active Rac1 interacts with Plexin-B1:Sema4D IEA Xenopus tropicalis 37565 R-XTR-4086392 https://reactome.org/PathwayBrowser/#/R-XTR-4086392 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 37565 R-XTR-4093336 https://reactome.org/PathwayBrowser/#/R-XTR-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Xenopus tropicalis 37565 R-XTR-4093339 https://reactome.org/PathwayBrowser/#/R-XTR-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Xenopus tropicalis 37565 R-XTR-416358 https://reactome.org/PathwayBrowser/#/R-XTR-416358 G alpha (q) inhibits PI3K alpha IEA Xenopus tropicalis 37565 R-XTR-416516 https://reactome.org/PathwayBrowser/#/R-XTR-416516 GRK2 sequesters activated Gq IEA Xenopus tropicalis 37565 R-XTR-416546 https://reactome.org/PathwayBrowser/#/R-XTR-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Xenopus tropicalis 37565 R-XTR-416559 https://reactome.org/PathwayBrowser/#/R-XTR-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Xenopus tropicalis 37565 R-XTR-416562 https://reactome.org/PathwayBrowser/#/R-XTR-416562 p190RhoGAP binds Plexin-B1 IEA Xenopus tropicalis 37565 R-XTR-416588 https://reactome.org/PathwayBrowser/#/R-XTR-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Xenopus tropicalis 37565 R-XTR-418574 https://reactome.org/PathwayBrowser/#/R-XTR-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Xenopus tropicalis 37565 R-XTR-418576 https://reactome.org/PathwayBrowser/#/R-XTR-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Xenopus tropicalis 37565 R-XTR-418582 https://reactome.org/PathwayBrowser/#/R-XTR-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Xenopus tropicalis 37565 R-XTR-418850 https://reactome.org/PathwayBrowser/#/R-XTR-418850 Activation of Cdc42 IEA Xenopus tropicalis 37565 R-XTR-418856 https://reactome.org/PathwayBrowser/#/R-XTR-418856 Activation of Rac1 IEA Xenopus tropicalis 37565 R-XTR-419049 https://reactome.org/PathwayBrowser/#/R-XTR-419049 ROCK activation by RHO IEA Xenopus tropicalis 37565 R-XTR-419166 https://reactome.org/PathwayBrowser/#/R-XTR-419166 GEFs activate RhoA,B,C IEA Xenopus tropicalis 37565 R-XTR-420883 https://reactome.org/PathwayBrowser/#/R-XTR-420883 Opsins act as GEFs for G alpha-t IEA Xenopus tropicalis 37565 R-XTR-421835 https://reactome.org/PathwayBrowser/#/R-XTR-421835 trans-Golgi Network Vesicle Scission IEA Xenopus tropicalis 37565 R-XTR-428750 https://reactome.org/PathwayBrowser/#/R-XTR-428750 Gq activation by TP receptor IEA Xenopus tropicalis 37565 R-XTR-428752 https://reactome.org/PathwayBrowser/#/R-XTR-428752 Dissociation of the TP:Gq complex IEA Xenopus tropicalis 37565 R-XTR-428917 https://reactome.org/PathwayBrowser/#/R-XTR-428917 G13 activation by TP receptor IEA Xenopus tropicalis 37565 R-XTR-428918 https://reactome.org/PathwayBrowser/#/R-XTR-428918 Dissociation of the TP:G13 complex IEA Xenopus tropicalis 37565 R-XTR-428941 https://reactome.org/PathwayBrowser/#/R-XTR-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Xenopus tropicalis 37565 R-XTR-432195 https://reactome.org/PathwayBrowser/#/R-XTR-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Xenopus tropicalis 37565 R-XTR-432707 https://reactome.org/PathwayBrowser/#/R-XTR-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Xenopus tropicalis 37565 R-XTR-432712 https://reactome.org/PathwayBrowser/#/R-XTR-432712 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane IEA Xenopus tropicalis 37565 R-XTR-442273 https://reactome.org/PathwayBrowser/#/R-XTR-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Xenopus tropicalis 37565 R-XTR-442314 https://reactome.org/PathwayBrowser/#/R-XTR-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Xenopus tropicalis 37565 R-XTR-443905 https://reactome.org/PathwayBrowser/#/R-XTR-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Xenopus tropicalis 37565 R-XTR-445071 https://reactome.org/PathwayBrowser/#/R-XTR-445071 Reinsertion of L1 into the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-445072 https://reactome.org/PathwayBrowser/#/R-XTR-445072 Interaction of PAK1 with Rac1-GTP IEA Xenopus tropicalis 37565 R-XTR-448958 https://reactome.org/PathwayBrowser/#/R-XTR-448958 Nuclear translocation of p38 MAPK IEA Xenopus tropicalis 37565 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 37565 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 37565 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 37565 R-XTR-5218804 https://reactome.org/PathwayBrowser/#/R-XTR-5218804 p38 MAPK activation by VEGFR IEA Xenopus tropicalis 37565 R-XTR-5218812 https://reactome.org/PathwayBrowser/#/R-XTR-5218812 FYN phosphorylates PAK2 IEA Xenopus tropicalis 37565 R-XTR-5218814 https://reactome.org/PathwayBrowser/#/R-XTR-5218814 PAK2 autophorylates IEA Xenopus tropicalis 37565 R-XTR-5218827 https://reactome.org/PathwayBrowser/#/R-XTR-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Xenopus tropicalis 37565 R-XTR-5218832 https://reactome.org/PathwayBrowser/#/R-XTR-5218832 CDC42:GTP binds PAK2 IEA Xenopus tropicalis 37565 R-XTR-5218839 https://reactome.org/PathwayBrowser/#/R-XTR-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Xenopus tropicalis 37565 R-XTR-5218841 https://reactome.org/PathwayBrowser/#/R-XTR-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Xenopus tropicalis 37565 R-XTR-5218850 https://reactome.org/PathwayBrowser/#/R-XTR-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Xenopus tropicalis 37565 R-XTR-5228992 https://reactome.org/PathwayBrowser/#/R-XTR-5228992 ROCK1,ROCK2 are activated IEA Xenopus tropicalis 37565 R-XTR-5250209 https://reactome.org/PathwayBrowser/#/R-XTR-5250209 ARL2:GTP:ARL2BP binds SLC25A4 IEA Xenopus tropicalis 37565 R-XTR-5250210 https://reactome.org/PathwayBrowser/#/R-XTR-5250210 ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix IEA Xenopus tropicalis 37565 R-XTR-5250217 https://reactome.org/PathwayBrowser/#/R-XTR-5250217 ARL2:GTP binds ARL2BP IEA Xenopus tropicalis 37565 R-XTR-5357445 https://reactome.org/PathwayBrowser/#/R-XTR-5357445 PAK1-3 dimer disassociates IEA Xenopus tropicalis 37565 R-XTR-5357472 https://reactome.org/PathwayBrowser/#/R-XTR-5357472 PAK1-3 autophosphorylates IEA Xenopus tropicalis 37565 R-XTR-5357483 https://reactome.org/PathwayBrowser/#/R-XTR-5357483 RAC1 binds PAK1-3 IEA Xenopus tropicalis 37565 R-XTR-5617816 https://reactome.org/PathwayBrowser/#/R-XTR-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Xenopus tropicalis 37565 R-XTR-5618328 https://reactome.org/PathwayBrowser/#/R-XTR-5618328 ATAT acetylates microtubules IEA Xenopus tropicalis 37565 R-XTR-5623519 https://reactome.org/PathwayBrowser/#/R-XTR-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Xenopus tropicalis 37565 R-XTR-5623521 https://reactome.org/PathwayBrowser/#/R-XTR-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Xenopus tropicalis 37565 R-XTR-5623524 https://reactome.org/PathwayBrowser/#/R-XTR-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Xenopus tropicalis 37565 R-XTR-5623525 https://reactome.org/PathwayBrowser/#/R-XTR-5623525 Cargo-carrying vesicles bud from the TGN IEA Xenopus tropicalis 37565 R-XTR-5623527 https://reactome.org/PathwayBrowser/#/R-XTR-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Xenopus tropicalis 37565 R-XTR-5623622 https://reactome.org/PathwayBrowser/#/R-XTR-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Xenopus tropicalis 37565 R-XTR-5623632 https://reactome.org/PathwayBrowser/#/R-XTR-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Xenopus tropicalis 37565 R-XTR-5623667 https://reactome.org/PathwayBrowser/#/R-XTR-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Xenopus tropicalis 37565 R-XTR-5624486 https://reactome.org/PathwayBrowser/#/R-XTR-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Xenopus tropicalis 37565 R-XTR-5624492 https://reactome.org/PathwayBrowser/#/R-XTR-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Xenopus tropicalis 37565 R-XTR-5624494 https://reactome.org/PathwayBrowser/#/R-XTR-5624494 RAF1 binds p21 RAS:GTP IEA Xenopus tropicalis 37565 R-XTR-5625959 https://reactome.org/PathwayBrowser/#/R-XTR-5625959 Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) IEA Xenopus tropicalis 37565 R-XTR-5626469 https://reactome.org/PathwayBrowser/#/R-XTR-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Xenopus tropicalis 37565 R-XTR-5626507 https://reactome.org/PathwayBrowser/#/R-XTR-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Xenopus tropicalis 37565 R-XTR-5627775 https://reactome.org/PathwayBrowser/#/R-XTR-5627775 Autophosphorylation of PAK1,2,3 IEA Xenopus tropicalis 37565 R-XTR-5638009 https://reactome.org/PathwayBrowser/#/R-XTR-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Xenopus tropicalis 37565 R-XTR-5638014 https://reactome.org/PathwayBrowser/#/R-XTR-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Xenopus tropicalis 37565 R-XTR-5653957 https://reactome.org/PathwayBrowser/#/R-XTR-5653957 Rag dimer formation IEA Xenopus tropicalis 37565 R-XTR-5653974 https://reactome.org/PathwayBrowser/#/R-XTR-5653974 Ragulator binds Rag dimers IEA Xenopus tropicalis 37565 R-XTR-5654392 https://reactome.org/PathwayBrowser/#/R-XTR-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-5654402 https://reactome.org/PathwayBrowser/#/R-XTR-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-5654413 https://reactome.org/PathwayBrowser/#/R-XTR-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-5654426 https://reactome.org/PathwayBrowser/#/R-XTR-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-5654600 https://reactome.org/PathwayBrowser/#/R-XTR-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-5654618 https://reactome.org/PathwayBrowser/#/R-XTR-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-5654647 https://reactome.org/PathwayBrowser/#/R-XTR-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-5654663 https://reactome.org/PathwayBrowser/#/R-XTR-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-5666169 https://reactome.org/PathwayBrowser/#/R-XTR-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Xenopus tropicalis 37565 R-XTR-5666197 https://reactome.org/PathwayBrowser/#/R-XTR-5666197 RHOA:GTP:RTKN binds LIN7B IEA Xenopus tropicalis 37565 R-XTR-5667008 https://reactome.org/PathwayBrowser/#/R-XTR-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Xenopus tropicalis 37565 R-XTR-5668605 https://reactome.org/PathwayBrowser/#/R-XTR-5668605 RAC2:GTP binds NOX2 complex IEA Xenopus tropicalis 37565 R-XTR-5668629 https://reactome.org/PathwayBrowser/#/R-XTR-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Xenopus tropicalis 37565 R-XTR-5668714 https://reactome.org/PathwayBrowser/#/R-XTR-5668714 RAC1:GTP binds NOX1 complex IEA Xenopus tropicalis 37565 R-XTR-5668718 https://reactome.org/PathwayBrowser/#/R-XTR-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 37565 R-XTR-5668731 https://reactome.org/PathwayBrowser/#/R-XTR-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 37565 R-XTR-5668735 https://reactome.org/PathwayBrowser/#/R-XTR-5668735 RAC1:GTP binds NOX3 complex IEA Xenopus tropicalis 37565 R-XTR-5672010 https://reactome.org/PathwayBrowser/#/R-XTR-5672010 Active MTORC1 phosphorylates ULK1 IEA Xenopus tropicalis 37565 R-XTR-5672017 https://reactome.org/PathwayBrowser/#/R-XTR-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Xenopus tropicalis 37565 R-XTR-5672027 https://reactome.org/PathwayBrowser/#/R-XTR-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Xenopus tropicalis 37565 R-XTR-5672817 https://reactome.org/PathwayBrowser/#/R-XTR-5672817 Active MTORC1 binds the ULK1 complex IEA Xenopus tropicalis 37565 R-XTR-5672824 https://reactome.org/PathwayBrowser/#/R-XTR-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Xenopus tropicalis 37565 R-XTR-5672828 https://reactome.org/PathwayBrowser/#/R-XTR-5672828 mTORC1 phosphorylates AKT1S1 IEA Xenopus tropicalis 37565 R-XTR-5672843 https://reactome.org/PathwayBrowser/#/R-XTR-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Xenopus tropicalis 37565 R-XTR-5672965 https://reactome.org/PathwayBrowser/#/R-XTR-5672965 RAS GEFs promote RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-5674018 https://reactome.org/PathwayBrowser/#/R-XTR-5674018 BRAP binds RAS:GTP IEA Xenopus tropicalis 37565 R-XTR-5674022 https://reactome.org/PathwayBrowser/#/R-XTR-5674022 BRAP autoubiquitinates IEA Xenopus tropicalis 37565 R-XTR-5675417 https://reactome.org/PathwayBrowser/#/R-XTR-5675417 PEBP1 binds activated RAF1 IEA Xenopus tropicalis 37565 R-XTR-5675433 https://reactome.org/PathwayBrowser/#/R-XTR-5675433 PP5 dephosphorylates RAF1 S338 IEA Xenopus tropicalis 37565 R-XTR-5675790 https://reactome.org/PathwayBrowser/#/R-XTR-5675790 MTORC1 dissociates from ULK complex IEA Xenopus tropicalis 37565 R-XTR-5694409 https://reactome.org/PathwayBrowser/#/R-XTR-5694409 Nucleotide exchange on RAB1 IEA Xenopus tropicalis 37565 R-XTR-5694522 https://reactome.org/PathwayBrowser/#/R-XTR-5694522 Inner coat assembly and cargo binding IEA Xenopus tropicalis 37565 R-XTR-5694527 https://reactome.org/PathwayBrowser/#/R-XTR-5694527 Loss of SAR1B GTPase IEA Xenopus tropicalis 37565 R-XTR-5696197 https://reactome.org/PathwayBrowser/#/R-XTR-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Xenopus tropicalis 37565 R-XTR-6787533 https://reactome.org/PathwayBrowser/#/R-XTR-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Xenopus tropicalis 37565 R-XTR-6788611 https://reactome.org/PathwayBrowser/#/R-XTR-6788611 HYKK phosphorylates 5HLYS IEA Xenopus tropicalis 37565 R-XTR-6789092 https://reactome.org/PathwayBrowser/#/R-XTR-6789092 NOX2 generates superoxide anion from oxygen IEA Xenopus tropicalis 37565 R-XTR-6809003 https://reactome.org/PathwayBrowser/#/R-XTR-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Xenopus tropicalis 37565 R-XTR-6809011 https://reactome.org/PathwayBrowser/#/R-XTR-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Xenopus tropicalis 37565 R-XTR-6811426 https://reactome.org/PathwayBrowser/#/R-XTR-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Xenopus tropicalis 37565 R-XTR-6814086 https://reactome.org/PathwayBrowser/#/R-XTR-6814086 ARFRP1 recruits ARL1 to the TGN IEA Xenopus tropicalis 37565 R-XTR-6814088 https://reactome.org/PathwayBrowser/#/R-XTR-6814088 SYS1 binds AcM-ARFRP1 IEA Xenopus tropicalis 37565 R-XTR-6814091 https://reactome.org/PathwayBrowser/#/R-XTR-6814091 ARL1 recruits TGN Golgin homodimers IEA Xenopus tropicalis 37565 R-XTR-6814096 https://reactome.org/PathwayBrowser/#/R-XTR-6814096 ARL1:GTP binds SCOC IEA Xenopus tropicalis 37565 R-XTR-6814559 https://reactome.org/PathwayBrowser/#/R-XTR-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Xenopus tropicalis 37565 R-XTR-70241 https://reactome.org/PathwayBrowser/#/R-XTR-70241 PCK1 phosphorylates OA to yield PEP IEA Xenopus tropicalis 37565 R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Xenopus tropicalis 37565 R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Xenopus tropicalis 37565 R-XTR-71775 https://reactome.org/PathwayBrowser/#/R-XTR-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Xenopus tropicalis 37565 R-XTR-72621 https://reactome.org/PathwayBrowser/#/R-XTR-72621 Ribosomal scanning IEA Xenopus tropicalis 37565 R-XTR-72663 https://reactome.org/PathwayBrowser/#/R-XTR-72663 De novo formation of eIF2:GTP IEA Xenopus tropicalis 37565 R-XTR-72669 https://reactome.org/PathwayBrowser/#/R-XTR-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Xenopus tropicalis 37565 R-XTR-72671 https://reactome.org/PathwayBrowser/#/R-XTR-72671 eIF5B:GTP is hydrolyzed and released IEA Xenopus tropicalis 37565 R-XTR-72672 https://reactome.org/PathwayBrowser/#/R-XTR-72672 The 60S subunit joins the translation initiation complex IEA Xenopus tropicalis 37565 R-XTR-72691 https://reactome.org/PathwayBrowser/#/R-XTR-72691 Formation of the 43S pre-initiation complex IEA Xenopus tropicalis 37565 R-XTR-72697 https://reactome.org/PathwayBrowser/#/R-XTR-72697 Start codon recognition IEA Xenopus tropicalis 37565 R-XTR-74059 https://reactome.org/PathwayBrowser/#/R-XTR-74059 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 37565 R-XTR-74885 https://reactome.org/PathwayBrowser/#/R-XTR-74885 GUCYs converts GTP to cGMP IEA Xenopus tropicalis 37565 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 37565 R-XTR-749453 https://reactome.org/PathwayBrowser/#/R-XTR-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Xenopus tropicalis 37565 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 37565 R-XTR-751019 https://reactome.org/PathwayBrowser/#/R-XTR-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Xenopus tropicalis 37565 R-XTR-751024 https://reactome.org/PathwayBrowser/#/R-XTR-751024 The Ligand:GPCR:Gz complex dissociates IEA Xenopus tropicalis 37565 R-XTR-751029 https://reactome.org/PathwayBrowser/#/R-XTR-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Xenopus tropicalis 37565 R-XTR-77081 https://reactome.org/PathwayBrowser/#/R-XTR-77081 Formation of the CE:GMP intermediate complex IEA Xenopus tropicalis 37565 R-XTR-8847887 https://reactome.org/PathwayBrowser/#/R-XTR-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Xenopus tropicalis 37565 R-XTR-8848618 https://reactome.org/PathwayBrowser/#/R-XTR-8848618 Activation of RAC1 by the PXN:CRK complex IEA Xenopus tropicalis 37565 R-XTR-8849082 https://reactome.org/PathwayBrowser/#/R-XTR-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Xenopus tropicalis 37565 R-XTR-8849085 https://reactome.org/PathwayBrowser/#/R-XTR-8849085 ARHGAP35 binds RHOA:GTP IEA Xenopus tropicalis 37565 R-XTR-8849748 https://reactome.org/PathwayBrowser/#/R-XTR-8849748 The COG complex binds RABs at the Golgi membrane IEA Xenopus tropicalis 37565 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 37565 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 37565 R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 37565 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 37565 R-XTR-8851827 https://reactome.org/PathwayBrowser/#/R-XTR-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Xenopus tropicalis 37565 R-XTR-8851877 https://reactome.org/PathwayBrowser/#/R-XTR-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Xenopus tropicalis 37565 R-XTR-8851899 https://reactome.org/PathwayBrowser/#/R-XTR-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Xenopus tropicalis 37565 R-XTR-8852280 https://reactome.org/PathwayBrowser/#/R-XTR-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Xenopus tropicalis 37565 R-XTR-8852298 https://reactome.org/PathwayBrowser/#/R-XTR-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Xenopus tropicalis 37565 R-XTR-8852306 https://reactome.org/PathwayBrowser/#/R-XTR-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Xenopus tropicalis 37565 R-XTR-8854173 https://reactome.org/PathwayBrowser/#/R-XTR-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Xenopus tropicalis 37565 R-XTR-8854182 https://reactome.org/PathwayBrowser/#/R-XTR-8854182 TBC1D17 binds OPTN:RAB8A IEA Xenopus tropicalis 37565 R-XTR-8854612 https://reactome.org/PathwayBrowser/#/R-XTR-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Xenopus tropicalis 37565 R-XTR-8865774 https://reactome.org/PathwayBrowser/#/R-XTR-8865774 TTLLs polyglutamylate tubulin IEA Xenopus tropicalis 37565 R-XTR-8867370 https://reactome.org/PathwayBrowser/#/R-XTR-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Xenopus tropicalis 37565 R-XTR-8875318 https://reactome.org/PathwayBrowser/#/R-XTR-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Xenopus tropicalis 37565 R-XTR-8875568 https://reactome.org/PathwayBrowser/#/R-XTR-8875568 RAPGEF1 activates RAP1 IEA Xenopus tropicalis 37565 R-XTR-8875591 https://reactome.org/PathwayBrowser/#/R-XTR-8875591 DOCK7 activates RAC1 IEA Xenopus tropicalis 37565 R-XTR-8875659 https://reactome.org/PathwayBrowser/#/R-XTR-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-8875661 https://reactome.org/PathwayBrowser/#/R-XTR-8875661 GGA3 associates with activated MET receptor IEA Xenopus tropicalis 37565 R-XTR-8876188 https://reactome.org/PathwayBrowser/#/R-XTR-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Xenopus tropicalis 37565 R-XTR-8876190 https://reactome.org/PathwayBrowser/#/R-XTR-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Xenopus tropicalis 37565 R-XTR-8876191 https://reactome.org/PathwayBrowser/#/R-XTR-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Xenopus tropicalis 37565 R-XTR-8876615 https://reactome.org/PathwayBrowser/#/R-XTR-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Xenopus tropicalis 37565 R-XTR-8877612 https://reactome.org/PathwayBrowser/#/R-XTR-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Xenopus tropicalis 37565 R-XTR-8941613 https://reactome.org/PathwayBrowser/#/R-XTR-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-8941618 https://reactome.org/PathwayBrowser/#/R-XTR-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-8941623 https://reactome.org/PathwayBrowser/#/R-XTR-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-8941628 https://reactome.org/PathwayBrowser/#/R-XTR-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Xenopus tropicalis 37565 R-XTR-8951498 https://reactome.org/PathwayBrowser/#/R-XTR-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Xenopus tropicalis 37565 R-XTR-8952716 https://reactome.org/PathwayBrowser/#/R-XTR-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Xenopus tropicalis 37565 R-XTR-8952726 https://reactome.org/PathwayBrowser/#/R-XTR-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Xenopus tropicalis 37565 R-XTR-8964280 https://reactome.org/PathwayBrowser/#/R-XTR-8964280 Active Gq binds BTK IEA Xenopus tropicalis 37565 R-XTR-8964284 https://reactome.org/PathwayBrowser/#/R-XTR-8964284 BTK in active Gq-BTK complex is activated IEA Xenopus tropicalis 37565 R-XTR-8964340 https://reactome.org/PathwayBrowser/#/R-XTR-8964340 Gq-BTK complex dissociates to Active BTK and Gq IEA Xenopus tropicalis 37565 R-XTR-8964599 https://reactome.org/PathwayBrowser/#/R-XTR-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Xenopus tropicalis 37565 R-XTR-8964604 https://reactome.org/PathwayBrowser/#/R-XTR-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Xenopus tropicalis 37565 R-XTR-8964614 https://reactome.org/PathwayBrowser/#/R-XTR-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Xenopus tropicalis 37565 R-XTR-8980691 https://reactome.org/PathwayBrowser/#/R-XTR-8980691 RHOA GEFs activate RHOA IEA Xenopus tropicalis 37565 R-XTR-8981353 https://reactome.org/PathwayBrowser/#/R-XTR-8981353 RASA1 stimulates RAS GTPase activity IEA Xenopus tropicalis 37565 R-XTR-8981355 https://reactome.org/PathwayBrowser/#/R-XTR-8981355 RASA1 binds RAS:GTP IEA Xenopus tropicalis 37565 R-XTR-8981637 https://reactome.org/PathwayBrowser/#/R-XTR-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Xenopus tropicalis 37565 R-XTR-8981892 https://reactome.org/PathwayBrowser/#/R-XTR-8981892 Active G alpha (z) binds RGS proteins IEA Xenopus tropicalis 37565 R-XTR-8981926 https://reactome.org/PathwayBrowser/#/R-XTR-8981926 RAC1 and CDC42 activate PAK3 IEA Xenopus tropicalis 37565 R-XTR-8982017 https://reactome.org/PathwayBrowser/#/R-XTR-8982017 Active G alpha (q) binds RGS proteins IEA Xenopus tropicalis 37565 R-XTR-8982019 https://reactome.org/PathwayBrowser/#/R-XTR-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Xenopus tropicalis 37565 R-XTR-8982020 https://reactome.org/PathwayBrowser/#/R-XTR-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Xenopus tropicalis 37565 R-XTR-8982021 https://reactome.org/PathwayBrowser/#/R-XTR-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Xenopus tropicalis 37565 R-XTR-8982025 https://reactome.org/PathwayBrowser/#/R-XTR-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Xenopus tropicalis 37565 R-XTR-8982640 https://reactome.org/PathwayBrowser/#/R-XTR-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Xenopus tropicalis 37565 R-XTR-8985594 https://reactome.org/PathwayBrowser/#/R-XTR-8985594 MYO9B inactivates RHOA IEA Xenopus tropicalis 37565 R-XTR-9013004 https://reactome.org/PathwayBrowser/#/R-XTR-9013004 RHOA binds effectors at the ER membrane IEA Xenopus tropicalis 37565 R-XTR-9013006 https://reactome.org/PathwayBrowser/#/R-XTR-9013006 RHOA:GTP translocates to the ER membrane IEA Xenopus tropicalis 37565 R-XTR-9013009 https://reactome.org/PathwayBrowser/#/R-XTR-9013009 RHOA binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9013022 https://reactome.org/PathwayBrowser/#/R-XTR-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Xenopus tropicalis 37565 R-XTR-9013023 https://reactome.org/PathwayBrowser/#/R-XTR-9013023 RHOB GEFs activate RHOB IEA Xenopus tropicalis 37565 R-XTR-9013024 https://reactome.org/PathwayBrowser/#/R-XTR-9013024 RHOB binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9013143 https://reactome.org/PathwayBrowser/#/R-XTR-9013143 RAC1 GEFs activate RAC1 IEA Xenopus tropicalis 37565 R-XTR-9013144 https://reactome.org/PathwayBrowser/#/R-XTR-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Xenopus tropicalis 37565 R-XTR-9013145 https://reactome.org/PathwayBrowser/#/R-XTR-9013145 RAC1 binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9013159 https://reactome.org/PathwayBrowser/#/R-XTR-9013159 CDC42 GEFs activate CDC42 IEA Xenopus tropicalis 37565 R-XTR-9013161 https://reactome.org/PathwayBrowser/#/R-XTR-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Xenopus tropicalis 37565 R-XTR-9013435 https://reactome.org/PathwayBrowser/#/R-XTR-9013435 RHOD auto-activates IEA Xenopus tropicalis 37565 R-XTR-9013437 https://reactome.org/PathwayBrowser/#/R-XTR-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Xenopus tropicalis 37565 R-XTR-9013452 https://reactome.org/PathwayBrowser/#/R-XTR-9013452 RHOD:GTP translocates to the endosome membrane IEA Xenopus tropicalis 37565 R-XTR-9014294 https://reactome.org/PathwayBrowser/#/R-XTR-9014294 RAC2 binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9014295 https://reactome.org/PathwayBrowser/#/R-XTR-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Xenopus tropicalis 37565 R-XTR-9014296 https://reactome.org/PathwayBrowser/#/R-XTR-9014296 RAC2 GEFs activate RAC2 IEA Xenopus tropicalis 37565 R-XTR-9014420 https://reactome.org/PathwayBrowser/#/R-XTR-9014420 RAC2 translocates to the phagocytic vesicle membrane IEA Xenopus tropicalis 37565 R-XTR-9014424 https://reactome.org/PathwayBrowser/#/R-XTR-9014424 RAC2 binds effectors at the phagocytic vesicle membrane IEA Xenopus tropicalis 37565 R-XTR-9014433 https://reactome.org/PathwayBrowser/#/R-XTR-9014433 RHOG GEFs activate RHOG IEA Xenopus tropicalis 37565 R-XTR-9014434 https://reactome.org/PathwayBrowser/#/R-XTR-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Xenopus tropicalis 37565 R-XTR-9014449 https://reactome.org/PathwayBrowser/#/R-XTR-9014449 RHOG binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9014454 https://reactome.org/PathwayBrowser/#/R-XTR-9014454 RHOG translocates to the ER membrane IEA Xenopus tropicalis 37565 R-XTR-9014467 https://reactome.org/PathwayBrowser/#/R-XTR-9014467 RHOG binds effectors at the ER membrane IEA Xenopus tropicalis 37565 R-XTR-9017488 https://reactome.org/PathwayBrowser/#/R-XTR-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Xenopus tropicalis 37565 R-XTR-9017491 https://reactome.org/PathwayBrowser/#/R-XTR-9017491 RHOJ GEFs activate RHOJ IEA Xenopus tropicalis 37565 R-XTR-9018745 https://reactome.org/PathwayBrowser/#/R-XTR-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Xenopus tropicalis 37565 R-XTR-9018746 https://reactome.org/PathwayBrowser/#/R-XTR-9018746 RHOQ binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9018747 https://reactome.org/PathwayBrowser/#/R-XTR-9018747 RHOQ GEFs activate RHOQ IEA Xenopus tropicalis 37565 R-XTR-9018754 https://reactome.org/PathwayBrowser/#/R-XTR-9018754 GDIs bind RHOH IEA Xenopus tropicalis 37565 R-XTR-9018756 https://reactome.org/PathwayBrowser/#/R-XTR-9018756 RHOH binds GTP IEA Xenopus tropicalis 37565 R-XTR-9018758 https://reactome.org/PathwayBrowser/#/R-XTR-9018758 RHOH binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9018766 https://reactome.org/PathwayBrowser/#/R-XTR-9018766 RHOU binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9018768 https://reactome.org/PathwayBrowser/#/R-XTR-9018768 RHOU auto-activates IEA Xenopus tropicalis 37565 R-XTR-9018774 https://reactome.org/PathwayBrowser/#/R-XTR-9018774 RHOBTB1 binds GTP IEA Xenopus tropicalis 37565 R-XTR-9018778 https://reactome.org/PathwayBrowser/#/R-XTR-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Xenopus tropicalis 37565 R-XTR-9018785 https://reactome.org/PathwayBrowser/#/R-XTR-9018785 RHOBTB2 binds GTP IEA Xenopus tropicalis 37565 R-XTR-9018787 https://reactome.org/PathwayBrowser/#/R-XTR-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Xenopus tropicalis 37565 R-XTR-9018794 https://reactome.org/PathwayBrowser/#/R-XTR-9018794 RHOV binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9018798 https://reactome.org/PathwayBrowser/#/R-XTR-9018798 RHOV binds GTP IEA Xenopus tropicalis 37565 R-XTR-9018804 https://reactome.org/PathwayBrowser/#/R-XTR-9018804 RAC3 GEFs activate RAC3 IEA Xenopus tropicalis 37565 R-XTR-9018806 https://reactome.org/PathwayBrowser/#/R-XTR-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Xenopus tropicalis 37565 R-XTR-9018808 https://reactome.org/PathwayBrowser/#/R-XTR-9018808 RAC3 binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9018824 https://reactome.org/PathwayBrowser/#/R-XTR-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Xenopus tropicalis 37565 R-XTR-9018826 https://reactome.org/PathwayBrowser/#/R-XTR-9018826 RHOT2 hydrolyzes GTP IEA Xenopus tropicalis 37565 R-XTR-9018836 https://reactome.org/PathwayBrowser/#/R-XTR-9018836 RHOQ translocates to the Golgi-associated vesicle membranes IEA Xenopus tropicalis 37565 R-XTR-9032798 https://reactome.org/PathwayBrowser/#/R-XTR-9032798 DOCK3 activates RAC1 IEA Xenopus tropicalis 37565 R-XTR-9036301 https://reactome.org/PathwayBrowser/#/R-XTR-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Xenopus tropicalis 37565 R-XTR-939265 https://reactome.org/PathwayBrowser/#/R-XTR-939265 Activation of Rap1 by membrane-associated GEFs IEA Xenopus tropicalis 37565 R-XTR-947535 https://reactome.org/PathwayBrowser/#/R-XTR-947535 Cyclisation of GTP to precursor Z IEA Xenopus tropicalis 37565 R-XTR-9607304 https://reactome.org/PathwayBrowser/#/R-XTR-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Xenopus tropicalis 37565 R-XTR-9624845 https://reactome.org/PathwayBrowser/#/R-XTR-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Xenopus tropicalis 37565 R-XTR-9624876 https://reactome.org/PathwayBrowser/#/R-XTR-9624876 RAN:GTP recruits nuclear envelope (NE) membranes IEA Xenopus tropicalis 37565 R-XTR-9624893 https://reactome.org/PathwayBrowser/#/R-XTR-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Xenopus tropicalis 37565 R-XTR-9626848 https://reactome.org/PathwayBrowser/#/R-XTR-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Xenopus tropicalis 37565 R-XTR-9639286 https://reactome.org/PathwayBrowser/#/R-XTR-9639286 RRAGC,D exchanges GTP for GDP IEA Xenopus tropicalis 37565 R-XTR-9640167 https://reactome.org/PathwayBrowser/#/R-XTR-9640167 RRAGA,B exchanges GDP for GTP IEA Xenopus tropicalis 37565 R-XTR-9640168 https://reactome.org/PathwayBrowser/#/R-XTR-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Xenopus tropicalis 37565 R-XTR-9640195 https://reactome.org/PathwayBrowser/#/R-XTR-9640195 RRAGA,B hydrolyzes GTP IEA Xenopus tropicalis 37565 R-XTR-9645598 https://reactome.org/PathwayBrowser/#/R-XTR-9645598 RRAGC,D hydrolyzes GTP IEA Xenopus tropicalis 37565 R-XTR-9646468 https://reactome.org/PathwayBrowser/#/R-XTR-9646468 mTORC1 binds RHEB:GTP IEA Xenopus tropicalis 37565 R-XTR-9646679 https://reactome.org/PathwayBrowser/#/R-XTR-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Xenopus tropicalis 37565 R-XTR-9646685 https://reactome.org/PathwayBrowser/#/R-XTR-9646685 Aggresome dissociates from dynein and microtubule IEA Xenopus tropicalis 37565 R-XTR-9648017 https://reactome.org/PathwayBrowser/#/R-XTR-9648017 EML4 binds to microtubules IEA Xenopus tropicalis 37565 R-XTR-9648114 https://reactome.org/PathwayBrowser/#/R-XTR-9648114 EML4 recruits NUDC to mitotic spindle IEA Xenopus tropicalis 37565 R-XTR-9649735 https://reactome.org/PathwayBrowser/#/R-XTR-9649735 Intrinsic nucleotide exchange on RAS IEA Xenopus tropicalis 37565 R-XTR-9649736 https://reactome.org/PathwayBrowser/#/R-XTR-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Xenopus tropicalis 37565 R-XTR-9658253 https://reactome.org/PathwayBrowser/#/R-XTR-9658253 RAS:GTP binds PI3K IEA Xenopus tropicalis 37565 R-XTR-9668419 https://reactome.org/PathwayBrowser/#/R-XTR-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Xenopus tropicalis 37565 R-XTR-9690493 https://reactome.org/PathwayBrowser/#/R-XTR-9690493 RHOB binds effectors on endosomes IEA Xenopus tropicalis 37565 R-XTR-9690494 https://reactome.org/PathwayBrowser/#/R-XTR-9690494 RHOB translocates to the endosome membrane IEA Xenopus tropicalis 37565 R-XTR-9691168 https://reactome.org/PathwayBrowser/#/R-XTR-9691168 RAC1 translocates to the endoplasmic reticulum membrane IEA Xenopus tropicalis 37565 R-XTR-9691174 https://reactome.org/PathwayBrowser/#/R-XTR-9691174 RAC1 binds effectors at the ER membrane IEA Xenopus tropicalis 37565 R-XTR-9692800 https://reactome.org/PathwayBrowser/#/R-XTR-9692800 CDC42 translocates to the endoplasmic reticulum membrane IEA Xenopus tropicalis 37565 R-XTR-9692809 https://reactome.org/PathwayBrowser/#/R-XTR-9692809 CDC42 binds effectors at the ER membrane IEA Xenopus tropicalis 37565 R-XTR-9693111 https://reactome.org/PathwayBrowser/#/R-XTR-9693111 RHOF auto-activates IEA Xenopus tropicalis 37565 R-XTR-9693125 https://reactome.org/PathwayBrowser/#/R-XTR-9693125 RHOF binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9693198 https://reactome.org/PathwayBrowser/#/R-XTR-9693198 RHOD binds effectors at the plasma membrane IEA Xenopus tropicalis 37565 R-XTR-9693207 https://reactome.org/PathwayBrowser/#/R-XTR-9693207 RHOD translocates to the mitochondrial outer membrane IEA Xenopus tropicalis 37565 R-XTR-9693214 https://reactome.org/PathwayBrowser/#/R-XTR-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Xenopus tropicalis 37565 R-XTR-9693243 https://reactome.org/PathwayBrowser/#/R-XTR-9693243 RHOD translocates to the Golgi membrane IEA Xenopus tropicalis 37565 R-XTR-9693250 https://reactome.org/PathwayBrowser/#/R-XTR-9693250 RHOD binds effectors at the Golgi membrane IEA Xenopus tropicalis 37565 R-XTR-9693282 https://reactome.org/PathwayBrowser/#/R-XTR-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Xenopus tropicalis 37565 R-XTR-9696267 https://reactome.org/PathwayBrowser/#/R-XTR-9696267 RND3 binds GTP IEA Xenopus tropicalis 37565 R-XTR-9696268 https://reactome.org/PathwayBrowser/#/R-XTR-9696268 RND3 binds effectors IEA Xenopus tropicalis 37565 R-XTR-9696271 https://reactome.org/PathwayBrowser/#/R-XTR-9696271 RND1 binds effectors IEA Xenopus tropicalis 37565 R-XTR-9696274 https://reactome.org/PathwayBrowser/#/R-XTR-9696274 RND1 binds GTP IEA Xenopus tropicalis 37565 R-XTR-9714477 https://reactome.org/PathwayBrowser/#/R-XTR-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Xenopus tropicalis 37565 R-XTR-9714480 https://reactome.org/PathwayBrowser/#/R-XTR-9714480 RAC2 translocates to the mitochondrial membrane IEA Xenopus tropicalis 37565 R-XTR-9714481 https://reactome.org/PathwayBrowser/#/R-XTR-9714481 RAC2 binds effectors at the ER membrane IEA Xenopus tropicalis 37565 R-XTR-9714483 https://reactome.org/PathwayBrowser/#/R-XTR-9714483 RAC2 translocates to the ER membrane IEA Xenopus tropicalis 37565 R-XTR-9714691 https://reactome.org/PathwayBrowser/#/R-XTR-9714691 RAC3 binds ER effectors IEA Xenopus tropicalis 37565 R-XTR-9714694 https://reactome.org/PathwayBrowser/#/R-XTR-9714694 RAC3 translocates to the endoplasmic reticulum membrane IEA Xenopus tropicalis 37565 R-XTR-983259 https://reactome.org/PathwayBrowser/#/R-XTR-983259 Kinesins move along microtubules consuming ATP IEA Xenopus tropicalis 37565 R-XTR-983266 https://reactome.org/PathwayBrowser/#/R-XTR-983266 Kinesins bind microtubules IEA Xenopus tropicalis 37565 R-XTR-983424 https://reactome.org/PathwayBrowser/#/R-XTR-983424 Budding of COPII coated vesicle IEA Xenopus tropicalis 37565 R-XTR-983425 https://reactome.org/PathwayBrowser/#/R-XTR-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Xenopus tropicalis 37568 R-BTA-163090 https://reactome.org/PathwayBrowser/#/R-BTA-163090 Elongation Of The Telomeric Chromosome End IEA Bos taurus 37568 R-BTA-164617 https://reactome.org/PathwayBrowser/#/R-BTA-164617 Elongation of Extended Telomeric Chromosome End IEA Bos taurus 37568 R-BTA-174427 https://reactome.org/PathwayBrowser/#/R-BTA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Bos taurus 37568 R-BTA-174444 https://reactome.org/PathwayBrowser/#/R-BTA-174444 Formation of C-strand Okazaki fragments IEA Bos taurus 37568 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 37568 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 37568 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 37568 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 37568 R-BTA-5358579 https://reactome.org/PathwayBrowser/#/R-BTA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Bos taurus 37568 R-BTA-68950 https://reactome.org/PathwayBrowser/#/R-BTA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Bos taurus 37568 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 37568 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 37568 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 37568 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 37568 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 37568 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 37568 R-CEL-68950 https://reactome.org/PathwayBrowser/#/R-CEL-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Caenorhabditis elegans 37568 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 37568 R-CFA-163090 https://reactome.org/PathwayBrowser/#/R-CFA-163090 Elongation Of The Telomeric Chromosome End IEA Canis familiaris 37568 R-CFA-164617 https://reactome.org/PathwayBrowser/#/R-CFA-164617 Elongation of Extended Telomeric Chromosome End IEA Canis familiaris 37568 R-CFA-174427 https://reactome.org/PathwayBrowser/#/R-CFA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Canis familiaris 37568 R-CFA-174444 https://reactome.org/PathwayBrowser/#/R-CFA-174444 Formation of C-strand Okazaki fragments IEA Canis familiaris 37568 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 37568 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 37568 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 37568 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 37568 R-CFA-5358579 https://reactome.org/PathwayBrowser/#/R-CFA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Canis familiaris 37568 R-CFA-68950 https://reactome.org/PathwayBrowser/#/R-CFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Canis familiaris 37568 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 37568 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 37568 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 37568 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 37568 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 37568 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 37568 R-DDI-68950 https://reactome.org/PathwayBrowser/#/R-DDI-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Dictyostelium discoideum 37568 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 37568 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 37568 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 37568 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 37568 R-DME-68950 https://reactome.org/PathwayBrowser/#/R-DME-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Drosophila melanogaster 37568 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 37568 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 37568 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 37568 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 37568 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 37568 R-GGA-163090 https://reactome.org/PathwayBrowser/#/R-GGA-163090 Elongation Of The Telomeric Chromosome End IEA Gallus gallus 37568 R-GGA-164617 https://reactome.org/PathwayBrowser/#/R-GGA-164617 Elongation of Extended Telomeric Chromosome End IEA Gallus gallus 37568 R-GGA-174427 https://reactome.org/PathwayBrowser/#/R-GGA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Gallus gallus 37568 R-GGA-417122 https://reactome.org/PathwayBrowser/#/R-GGA-417122 Elongation and translocation of the telomeric chromosome end IEA Gallus gallus 37568 R-GGA-417127 https://reactome.org/PathwayBrowser/#/R-GGA-417127 Elongation and translocation of the extended telomeric chromosome end IEA Gallus gallus 37568 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 37568 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 37568 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 37568 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 37568 R-GGA-68950 https://reactome.org/PathwayBrowser/#/R-GGA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Gallus gallus 37568 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 37568 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 37568 R-HSA-163090 https://reactome.org/PathwayBrowser/#/R-HSA-163090 Elongation Of The Telomeric Chromosome End TAS Homo sapiens 37568 R-HSA-164617 https://reactome.org/PathwayBrowser/#/R-HSA-164617 Elongation of Extended Telomeric Chromosome End TAS Homo sapiens 37568 R-HSA-174427 https://reactome.org/PathwayBrowser/#/R-HSA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere TAS Homo sapiens 37568 R-HSA-174444 https://reactome.org/PathwayBrowser/#/R-HSA-174444 Formation of C-strand Okazaki fragments TAS Homo sapiens 37568 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 37568 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 37568 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 37568 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 37568 R-HSA-5358579 https://reactome.org/PathwayBrowser/#/R-HSA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap TAS Homo sapiens 37568 R-HSA-68950 https://reactome.org/PathwayBrowser/#/R-HSA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin TAS Homo sapiens 37568 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 37568 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 37568 R-HSA-9710480 https://reactome.org/PathwayBrowser/#/R-HSA-9710480 Decitabine triphosphate incorporates into DNA TAS Homo sapiens 37568 R-MMU-163090 https://reactome.org/PathwayBrowser/#/R-MMU-163090 Elongation Of The Telomeric Chromosome End IEA Mus musculus 37568 R-MMU-164617 https://reactome.org/PathwayBrowser/#/R-MMU-164617 Elongation of Extended Telomeric Chromosome End IEA Mus musculus 37568 R-MMU-174427 https://reactome.org/PathwayBrowser/#/R-MMU-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Mus musculus 37568 R-MMU-174444 https://reactome.org/PathwayBrowser/#/R-MMU-174444 Formation of C-strand Okazaki fragments IEA Mus musculus 37568 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 37568 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 37568 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 37568 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 37568 R-MMU-5358579 https://reactome.org/PathwayBrowser/#/R-MMU-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Mus musculus 37568 R-MMU-68950 https://reactome.org/PathwayBrowser/#/R-MMU-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Mus musculus 37568 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 37568 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 37568 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 37568 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 37568 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 37568 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 37568 R-PFA-68950 https://reactome.org/PathwayBrowser/#/R-PFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Plasmodium falciparum 37568 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 37568 R-RNO-163090 https://reactome.org/PathwayBrowser/#/R-RNO-163090 Elongation Of The Telomeric Chromosome End IEA Rattus norvegicus 37568 R-RNO-164617 https://reactome.org/PathwayBrowser/#/R-RNO-164617 Elongation of Extended Telomeric Chromosome End IEA Rattus norvegicus 37568 R-RNO-174427 https://reactome.org/PathwayBrowser/#/R-RNO-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Rattus norvegicus 37568 R-RNO-174444 https://reactome.org/PathwayBrowser/#/R-RNO-174444 Formation of C-strand Okazaki fragments IEA Rattus norvegicus 37568 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 37568 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 37568 R-RNO-5358579 https://reactome.org/PathwayBrowser/#/R-RNO-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Rattus norvegicus 37568 R-RNO-68950 https://reactome.org/PathwayBrowser/#/R-RNO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Rattus norvegicus 37568 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 37568 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 37568 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 37568 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 37568 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 37568 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 37568 R-SCE-68950 https://reactome.org/PathwayBrowser/#/R-SCE-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Saccharomyces cerevisiae 37568 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 37568 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 37568 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 37568 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 37568 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 37568 R-SPO-5358579 https://reactome.org/PathwayBrowser/#/R-SPO-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Schizosaccharomyces pombe 37568 R-SPO-68950 https://reactome.org/PathwayBrowser/#/R-SPO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Schizosaccharomyces pombe 37568 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 37568 R-SSC-163090 https://reactome.org/PathwayBrowser/#/R-SSC-163090 Elongation Of The Telomeric Chromosome End IEA Sus scrofa 37568 R-SSC-164617 https://reactome.org/PathwayBrowser/#/R-SSC-164617 Elongation of Extended Telomeric Chromosome End IEA Sus scrofa 37568 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa 37568 R-SSC-174444 https://reactome.org/PathwayBrowser/#/R-SSC-174444 Formation of C-strand Okazaki fragments IEA Sus scrofa 37568 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 37568 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 37568 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 37568 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 37568 R-SSC-5358579 https://reactome.org/PathwayBrowser/#/R-SSC-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Sus scrofa 37568 R-SSC-68950 https://reactome.org/PathwayBrowser/#/R-SSC-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Sus scrofa 37568 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 37568 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 37568 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 37568 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 37568 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 37568 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 37623 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 37623 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 37623 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 37623 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 37623 R-BTA-8851679 https://reactome.org/PathwayBrowser/#/R-BTA-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Bos taurus 37623 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 37623 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 37623 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 37623 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 37623 R-CFA-8851679 https://reactome.org/PathwayBrowser/#/R-CFA-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Canis familiaris 37623 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 37623 R-DRE-8851679 https://reactome.org/PathwayBrowser/#/R-DRE-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Danio rerio 37623 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 37623 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 37623 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 37623 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 37623 R-GGA-8851679 https://reactome.org/PathwayBrowser/#/R-GGA-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Gallus gallus 37623 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 37623 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 37623 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 37623 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 37623 R-HSA-8851679 https://reactome.org/PathwayBrowser/#/R-HSA-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol TAS Homo sapiens 37623 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 37623 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 37623 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 37623 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 37623 R-MMU-8851679 https://reactome.org/PathwayBrowser/#/R-MMU-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Mus musculus 37623 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 37623 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 37623 R-RNO-8851679 https://reactome.org/PathwayBrowser/#/R-RNO-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Rattus norvegicus 37623 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 37623 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 37623 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 37623 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 37623 R-SSC-8851679 https://reactome.org/PathwayBrowser/#/R-SSC-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Sus scrofa 37623 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 37623 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 37623 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 37623 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 37623 R-XTR-8851679 https://reactome.org/PathwayBrowser/#/R-XTR-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Xenopus tropicalis 37633 R-BTA-446188 https://reactome.org/PathwayBrowser/#/R-BTA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Bos taurus 37633 R-CEL-446188 https://reactome.org/PathwayBrowser/#/R-CEL-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Caenorhabditis elegans 37633 R-CFA-446188 https://reactome.org/PathwayBrowser/#/R-CFA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Canis familiaris 37633 R-DDI-446188 https://reactome.org/PathwayBrowser/#/R-DDI-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Dictyostelium discoideum 37633 R-DME-446188 https://reactome.org/PathwayBrowser/#/R-DME-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Drosophila melanogaster 37633 R-DRE-446188 https://reactome.org/PathwayBrowser/#/R-DRE-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Danio rerio 37633 R-GGA-446188 https://reactome.org/PathwayBrowser/#/R-GGA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Gallus gallus 37633 R-HSA-446187 https://reactome.org/PathwayBrowser/#/R-HSA-446187 ALG11 transfers the fourth and fifth Man to the N-glycan precursor IEA Homo sapiens 37633 R-HSA-446188 https://reactome.org/PathwayBrowser/#/R-HSA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 TAS Homo sapiens 37633 R-HSA-446212 https://reactome.org/PathwayBrowser/#/R-HSA-446212 Flipping of the N-glycan precursor to inside the ER IEA Homo sapiens 37633 R-HSA-4570573 https://reactome.org/PathwayBrowser/#/R-HSA-4570573 Defective RFT1 does not flip the N-glycan precursor TAS Homo sapiens 37633 R-HSA-4720473 https://reactome.org/PathwayBrowser/#/R-HSA-4720473 Defective ALG3 does not add mannose to the N-glycan precursor TAS Homo sapiens 37633 R-HSA-9036025 https://reactome.org/PathwayBrowser/#/R-HSA-9036025 Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)5 (PP-Dol)1 by ALG3 TAS Homo sapiens 37633 R-MMU-446188 https://reactome.org/PathwayBrowser/#/R-MMU-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Mus musculus 37633 R-RNO-446188 https://reactome.org/PathwayBrowser/#/R-RNO-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Rattus norvegicus 37633 R-SCE-446188 https://reactome.org/PathwayBrowser/#/R-SCE-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Saccharomyces cerevisiae 37633 R-SCE-449324 https://reactome.org/PathwayBrowser/#/R-SCE-449324 Addition of the fourth and fifth mannose to the N-glycan precursor skeleton by Alg11 TAS Saccharomyces cerevisiae 37633 R-SCE-449765 https://reactome.org/PathwayBrowser/#/R-SCE-449765 Flipping of the N-glycan precursor into the ER lumen TAS Saccharomyces cerevisiae 37633 R-SPO-446188 https://reactome.org/PathwayBrowser/#/R-SPO-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Schizosaccharomyces pombe 37633 R-SSC-446188 https://reactome.org/PathwayBrowser/#/R-SSC-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Sus scrofa 37633 R-XTR-446188 https://reactome.org/PathwayBrowser/#/R-XTR-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Xenopus tropicalis 37637 R-BTA-446202 https://reactome.org/PathwayBrowser/#/R-BTA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Bos taurus 37637 R-BTA-446216 https://reactome.org/PathwayBrowser/#/R-BTA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Bos taurus 37637 R-CEL-446202 https://reactome.org/PathwayBrowser/#/R-CEL-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Caenorhabditis elegans 37637 R-CEL-446216 https://reactome.org/PathwayBrowser/#/R-CEL-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Caenorhabditis elegans 37637 R-CFA-446202 https://reactome.org/PathwayBrowser/#/R-CFA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Canis familiaris 37637 R-CFA-446216 https://reactome.org/PathwayBrowser/#/R-CFA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Canis familiaris 37637 R-DDI-446202 https://reactome.org/PathwayBrowser/#/R-DDI-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Dictyostelium discoideum 37637 R-DDI-446216 https://reactome.org/PathwayBrowser/#/R-DDI-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Dictyostelium discoideum 37637 R-DME-446202 https://reactome.org/PathwayBrowser/#/R-DME-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Drosophila melanogaster 37637 R-DME-446216 https://reactome.org/PathwayBrowser/#/R-DME-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Drosophila melanogaster 37637 R-GGA-446202 https://reactome.org/PathwayBrowser/#/R-GGA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Gallus gallus 37637 R-GGA-446216 https://reactome.org/PathwayBrowser/#/R-GGA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Gallus gallus 37637 R-HSA-446202 https://reactome.org/PathwayBrowser/#/R-HSA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 TAS Homo sapiens 37637 R-HSA-446216 https://reactome.org/PathwayBrowser/#/R-HSA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 TAS Homo sapiens 37637 R-HSA-4724291 https://reactome.org/PathwayBrowser/#/R-HSA-4724291 Defective ALG6 does not add glucose to the N-glycan precursor TAS Homo sapiens 37637 R-MMU-446202 https://reactome.org/PathwayBrowser/#/R-MMU-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Mus musculus 37637 R-MMU-446216 https://reactome.org/PathwayBrowser/#/R-MMU-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Mus musculus 37637 R-RNO-446202 https://reactome.org/PathwayBrowser/#/R-RNO-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Rattus norvegicus 37637 R-RNO-446216 https://reactome.org/PathwayBrowser/#/R-RNO-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Rattus norvegicus 37637 R-SCE-446202 https://reactome.org/PathwayBrowser/#/R-SCE-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Saccharomyces cerevisiae 37637 R-SCE-446216 https://reactome.org/PathwayBrowser/#/R-SCE-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Saccharomyces cerevisiae 37637 R-SPO-446202 https://reactome.org/PathwayBrowser/#/R-SPO-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Schizosaccharomyces pombe 37637 R-SPO-446216 https://reactome.org/PathwayBrowser/#/R-SPO-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Schizosaccharomyces pombe 37637 R-SSC-446202 https://reactome.org/PathwayBrowser/#/R-SSC-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Sus scrofa 37637 R-SSC-446216 https://reactome.org/PathwayBrowser/#/R-SSC-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Sus scrofa 37637 R-XTR-446202 https://reactome.org/PathwayBrowser/#/R-XTR-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Xenopus tropicalis 37637 R-XTR-446216 https://reactome.org/PathwayBrowser/#/R-XTR-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Xenopus tropicalis 37640 R-BTA-192178 https://reactome.org/PathwayBrowser/#/R-BTA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Bos taurus 37640 R-BTA-193789 https://reactome.org/PathwayBrowser/#/R-BTA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Bos taurus 37640 R-CFA-192178 https://reactome.org/PathwayBrowser/#/R-CFA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Canis familiaris 37640 R-CFA-193789 https://reactome.org/PathwayBrowser/#/R-CFA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Canis familiaris 37640 R-DRE-193789 https://reactome.org/PathwayBrowser/#/R-DRE-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Danio rerio 37640 R-GGA-192178 https://reactome.org/PathwayBrowser/#/R-GGA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Gallus gallus 37640 R-HSA-192178 https://reactome.org/PathwayBrowser/#/R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL TAS Homo sapiens 37640 R-HSA-193789 https://reactome.org/PathwayBrowser/#/R-HSA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one TAS Homo sapiens 37640 R-MMU-192178 https://reactome.org/PathwayBrowser/#/R-MMU-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Mus musculus 37640 R-MMU-193789 https://reactome.org/PathwayBrowser/#/R-MMU-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Mus musculus 37640 R-RNO-192178 https://reactome.org/PathwayBrowser/#/R-RNO-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Rattus norvegicus 37640 R-RNO-193789 https://reactome.org/PathwayBrowser/#/R-RNO-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 37640 R-SSC-192178 https://reactome.org/PathwayBrowser/#/R-SSC-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Sus scrofa 37640 R-SSC-193789 https://reactome.org/PathwayBrowser/#/R-SSC-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Sus scrofa 37640 R-XTR-192178 https://reactome.org/PathwayBrowser/#/R-XTR-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Xenopus tropicalis 37640 R-XTR-193789 https://reactome.org/PathwayBrowser/#/R-XTR-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 37642 R-BTA-192056 https://reactome.org/PathwayBrowser/#/R-BTA-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Bos taurus 37642 R-BTA-192137 https://reactome.org/PathwayBrowser/#/R-BTA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 37642 R-BTA-193401 https://reactome.org/PathwayBrowser/#/R-BTA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 37642 R-CEL-192056 https://reactome.org/PathwayBrowser/#/R-CEL-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Caenorhabditis elegans 37642 R-CEL-192137 https://reactome.org/PathwayBrowser/#/R-CEL-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 37642 R-CEL-193401 https://reactome.org/PathwayBrowser/#/R-CEL-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 37642 R-CFA-192137 https://reactome.org/PathwayBrowser/#/R-CFA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 37642 R-CFA-193401 https://reactome.org/PathwayBrowser/#/R-CFA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 37642 R-DME-192056 https://reactome.org/PathwayBrowser/#/R-DME-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Drosophila melanogaster 37642 R-DME-192137 https://reactome.org/PathwayBrowser/#/R-DME-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 37642 R-DME-193401 https://reactome.org/PathwayBrowser/#/R-DME-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 37642 R-DRE-192056 https://reactome.org/PathwayBrowser/#/R-DRE-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Danio rerio 37642 R-DRE-192137 https://reactome.org/PathwayBrowser/#/R-DRE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 37642 R-GGA-192056 https://reactome.org/PathwayBrowser/#/R-GGA-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Gallus gallus 37642 R-GGA-192137 https://reactome.org/PathwayBrowser/#/R-GGA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 37642 R-GGA-193401 https://reactome.org/PathwayBrowser/#/R-GGA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 37642 R-HSA-192056 https://reactome.org/PathwayBrowser/#/R-HSA-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA TAS Homo sapiens 37642 R-HSA-192137 https://reactome.org/PathwayBrowser/#/R-HSA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 37642 R-HSA-192325 https://reactome.org/PathwayBrowser/#/R-HSA-192325 25(R) THCA-CoA is translocated from the cytosol to the peroxisome TAS Homo sapiens 37642 R-HSA-193401 https://reactome.org/PathwayBrowser/#/R-HSA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 37642 R-MMU-192056 https://reactome.org/PathwayBrowser/#/R-MMU-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Mus musculus 37642 R-MMU-192137 https://reactome.org/PathwayBrowser/#/R-MMU-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 37642 R-MMU-193401 https://reactome.org/PathwayBrowser/#/R-MMU-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 37642 R-RNO-192056 https://reactome.org/PathwayBrowser/#/R-RNO-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Rattus norvegicus 37642 R-RNO-192137 https://reactome.org/PathwayBrowser/#/R-RNO-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 37642 R-RNO-193401 https://reactome.org/PathwayBrowser/#/R-RNO-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 37642 R-SCE-192137 https://reactome.org/PathwayBrowser/#/R-SCE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 37642 R-SCE-193401 https://reactome.org/PathwayBrowser/#/R-SCE-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 37642 R-SSC-192137 https://reactome.org/PathwayBrowser/#/R-SSC-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 37642 R-SSC-193401 https://reactome.org/PathwayBrowser/#/R-SSC-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 37642 R-XTR-192056 https://reactome.org/PathwayBrowser/#/R-XTR-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Xenopus tropicalis 37642 R-XTR-192137 https://reactome.org/PathwayBrowser/#/R-XTR-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 37642 R-XTR-193401 https://reactome.org/PathwayBrowser/#/R-XTR-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 37643 R-BTA-192056 https://reactome.org/PathwayBrowser/#/R-BTA-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Bos taurus 37643 R-BTA-192335 https://reactome.org/PathwayBrowser/#/R-BTA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Bos taurus 37643 R-CEL-192056 https://reactome.org/PathwayBrowser/#/R-CEL-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Caenorhabditis elegans 37643 R-CEL-192335 https://reactome.org/PathwayBrowser/#/R-CEL-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Caenorhabditis elegans 37643 R-CFA-192335 https://reactome.org/PathwayBrowser/#/R-CFA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Canis familiaris 37643 R-DDI-192335 https://reactome.org/PathwayBrowser/#/R-DDI-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Dictyostelium discoideum 37643 R-DME-192056 https://reactome.org/PathwayBrowser/#/R-DME-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Drosophila melanogaster 37643 R-DME-192335 https://reactome.org/PathwayBrowser/#/R-DME-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Drosophila melanogaster 37643 R-DRE-192056 https://reactome.org/PathwayBrowser/#/R-DRE-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Danio rerio 37643 R-GGA-192056 https://reactome.org/PathwayBrowser/#/R-GGA-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Gallus gallus 37643 R-GGA-192335 https://reactome.org/PathwayBrowser/#/R-GGA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Gallus gallus 37643 R-HSA-192056 https://reactome.org/PathwayBrowser/#/R-HSA-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA TAS Homo sapiens 37643 R-HSA-192335 https://reactome.org/PathwayBrowser/#/R-HSA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) TAS Homo sapiens 37643 R-MMU-192056 https://reactome.org/PathwayBrowser/#/R-MMU-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Mus musculus 37643 R-MMU-192335 https://reactome.org/PathwayBrowser/#/R-MMU-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Mus musculus 37643 R-RNO-192056 https://reactome.org/PathwayBrowser/#/R-RNO-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Rattus norvegicus 37643 R-RNO-192335 https://reactome.org/PathwayBrowser/#/R-RNO-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Rattus norvegicus 37643 R-SSC-192335 https://reactome.org/PathwayBrowser/#/R-SSC-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Sus scrofa 37643 R-XTR-192056 https://reactome.org/PathwayBrowser/#/R-XTR-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA IEA Xenopus tropicalis 37643 R-XTR-192335 https://reactome.org/PathwayBrowser/#/R-XTR-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Xenopus tropicalis 37646 R-BTA-1482691 https://reactome.org/PathwayBrowser/#/R-BTA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Bos taurus 37646 R-BTA-1482897 https://reactome.org/PathwayBrowser/#/R-BTA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Bos taurus 37646 R-CEL-1482691 https://reactome.org/PathwayBrowser/#/R-CEL-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Caenorhabditis elegans 37646 R-CFA-1482691 https://reactome.org/PathwayBrowser/#/R-CFA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Canis familiaris 37646 R-CFA-1482897 https://reactome.org/PathwayBrowser/#/R-CFA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Canis familiaris 37646 R-CFA-8869425 https://reactome.org/PathwayBrowser/#/R-CFA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Canis familiaris 37646 R-DDI-1482691 https://reactome.org/PathwayBrowser/#/R-DDI-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Dictyostelium discoideum 37646 R-DME-1482691 https://reactome.org/PathwayBrowser/#/R-DME-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Drosophila melanogaster 37646 R-DME-8869425 https://reactome.org/PathwayBrowser/#/R-DME-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Drosophila melanogaster 37646 R-DRE-1482897 https://reactome.org/PathwayBrowser/#/R-DRE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Danio rerio 37646 R-DRE-8869425 https://reactome.org/PathwayBrowser/#/R-DRE-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Danio rerio 37646 R-GGA-1482691 https://reactome.org/PathwayBrowser/#/R-GGA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus 37646 R-GGA-1482897 https://reactome.org/PathwayBrowser/#/R-GGA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Gallus gallus 37646 R-GGA-8869425 https://reactome.org/PathwayBrowser/#/R-GGA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Gallus gallus 37646 R-HSA-1482691 https://reactome.org/PathwayBrowser/#/R-HSA-1482691 2-acyl LPS is acylated to PS by LPSAT TAS Homo sapiens 37646 R-HSA-1482897 https://reactome.org/PathwayBrowser/#/R-HSA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] TAS Homo sapiens 37646 R-HSA-8869425 https://reactome.org/PathwayBrowser/#/R-HSA-8869425 PLA1A hydrolyses PS to 2-acyl LPS TAS Homo sapiens 37646 R-MMU-1482691 https://reactome.org/PathwayBrowser/#/R-MMU-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Mus musculus 37646 R-MMU-1482897 https://reactome.org/PathwayBrowser/#/R-MMU-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Mus musculus 37646 R-MMU-8869425 https://reactome.org/PathwayBrowser/#/R-MMU-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Mus musculus 37646 R-PFA-1482691 https://reactome.org/PathwayBrowser/#/R-PFA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Plasmodium falciparum 37646 R-RNO-1482691 https://reactome.org/PathwayBrowser/#/R-RNO-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Rattus norvegicus 37646 R-RNO-1482897 https://reactome.org/PathwayBrowser/#/R-RNO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Rattus norvegicus 37646 R-RNO-8869425 https://reactome.org/PathwayBrowser/#/R-RNO-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Rattus norvegicus 37646 R-SCE-1482691 https://reactome.org/PathwayBrowser/#/R-SCE-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Saccharomyces cerevisiae 37646 R-SCE-1482897 https://reactome.org/PathwayBrowser/#/R-SCE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Saccharomyces cerevisiae 37646 R-SPO-1482691 https://reactome.org/PathwayBrowser/#/R-SPO-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Schizosaccharomyces pombe 37646 R-SPO-1482897 https://reactome.org/PathwayBrowser/#/R-SPO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Schizosaccharomyces pombe 37646 R-SSC-1482691 https://reactome.org/PathwayBrowser/#/R-SSC-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa 37646 R-SSC-1482897 https://reactome.org/PathwayBrowser/#/R-SSC-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Sus scrofa 37646 R-SSC-8869425 https://reactome.org/PathwayBrowser/#/R-SSC-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Sus scrofa 37646 R-XTR-1482691 https://reactome.org/PathwayBrowser/#/R-XTR-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Xenopus tropicalis 37646 R-XTR-1482897 https://reactome.org/PathwayBrowser/#/R-XTR-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Xenopus tropicalis 3766 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 3766 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 3766 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 3766 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 3766 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 3766 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 3766 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 3766 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 3766 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 3766 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 3766 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 3766 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 3766 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 3766 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 3766 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 3766 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 3766 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 3766 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 3766 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 3766 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 3766 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 3766 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 3766 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 3766 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 3766 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 3766 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 3766 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 3766 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 37671 R-BTA-166726 https://reactome.org/PathwayBrowser/#/R-BTA-166726 Activation of MASPs IEA Bos taurus 37671 R-BTA-166753 https://reactome.org/PathwayBrowser/#/R-BTA-166753 Conversion of C4 into C4a and C4b IEA Bos taurus 37671 R-BTA-166792 https://reactome.org/PathwayBrowser/#/R-BTA-166792 Conversion of C2 into C2a and C2b IEA Bos taurus 37671 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 37671 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 37671 R-BTA-2855054 https://reactome.org/PathwayBrowser/#/R-BTA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Bos taurus 37671 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 37671 R-BTA-5607750 https://reactome.org/PathwayBrowser/#/R-BTA-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Bos taurus 37671 R-CFA-166726 https://reactome.org/PathwayBrowser/#/R-CFA-166726 Activation of MASPs IEA Canis familiaris 37671 R-CFA-166753 https://reactome.org/PathwayBrowser/#/R-CFA-166753 Conversion of C4 into C4a and C4b IEA Canis familiaris 37671 R-CFA-166792 https://reactome.org/PathwayBrowser/#/R-CFA-166792 Conversion of C2 into C2a and C2b IEA Canis familiaris 37671 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 37671 R-CFA-2855054 https://reactome.org/PathwayBrowser/#/R-CFA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Canis familiaris 37671 R-CFA-5607750 https://reactome.org/PathwayBrowser/#/R-CFA-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Canis familiaris 37671 R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 37671 R-GGA-166726 https://reactome.org/PathwayBrowser/#/R-GGA-166726 Activation of MASPs IEA Gallus gallus 37671 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus 37671 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus 37671 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 37671 R-GGA-2855054 https://reactome.org/PathwayBrowser/#/R-GGA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Gallus gallus 37671 R-HSA-166726 https://reactome.org/PathwayBrowser/#/R-HSA-166726 Activation of MASPs TAS Homo sapiens 37671 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens 37671 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens 37671 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 37671 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 37671 R-HSA-2197645 https://reactome.org/PathwayBrowser/#/R-HSA-2197645 SCARF1 (SREC-I) binds ligands IEA Homo sapiens 37671 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 37671 R-HSA-2247514 https://reactome.org/PathwayBrowser/#/R-HSA-2247514 SCARF1:ligand is endocytosed TAS Homo sapiens 37671 R-HSA-2855054 https://reactome.org/PathwayBrowser/#/R-HSA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface TAS Homo sapiens 37671 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 37671 R-HSA-5607738 https://reactome.org/PathwayBrowser/#/R-HSA-5607738 SYK binds p-Y15-CLEC7A:1,3-beta-D-glucan IEA Homo sapiens 37671 R-HSA-5607745 https://reactome.org/PathwayBrowser/#/R-HSA-5607745 1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG IEA Homo sapiens 37671 R-HSA-5607750 https://reactome.org/PathwayBrowser/#/R-HSA-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan TAS Homo sapiens 37671 R-HSA-5607758 https://reactome.org/PathwayBrowser/#/R-HSA-5607758 CLEC7A binds 1,3-beta-D-glucan IEA Homo sapiens 37671 R-MMU-166726 https://reactome.org/PathwayBrowser/#/R-MMU-166726 Activation of MASPs IEA Mus musculus 37671 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus 37671 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus 37671 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 37671 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 37671 R-MMU-2855054 https://reactome.org/PathwayBrowser/#/R-MMU-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Mus musculus 37671 R-MMU-5607739 https://reactome.org/PathwayBrowser/#/R-MMU-5607739 Clec7a binds 1,3-beta-D-glucan TAS Mus musculus 37671 R-MMU-5607750 https://reactome.org/PathwayBrowser/#/R-MMU-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Mus musculus 37671 R-MMU-5607754 https://reactome.org/PathwayBrowser/#/R-MMU-5607754 1,3-beta-D-glucan:p-15Y-Clec7a:Syk phosphorylates Plcg2 TAS Mus musculus 37671 R-MMU-8878599 https://reactome.org/PathwayBrowser/#/R-MMU-8878599 Ssc5d binds ligands TAS Mus musculus 37671 R-RNO-166726 https://reactome.org/PathwayBrowser/#/R-RNO-166726 Activation of MASPs IEA Rattus norvegicus 37671 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus 37671 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus 37671 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 37671 R-RNO-2855054 https://reactome.org/PathwayBrowser/#/R-RNO-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Rattus norvegicus 37671 R-RNO-5607750 https://reactome.org/PathwayBrowser/#/R-RNO-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Rattus norvegicus 37671 R-SSC-166726 https://reactome.org/PathwayBrowser/#/R-SSC-166726 Activation of MASPs IEA Sus scrofa 37671 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa 37671 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa 37671 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 37671 R-SSC-2855054 https://reactome.org/PathwayBrowser/#/R-SSC-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Sus scrofa 37671 R-SSC-5607750 https://reactome.org/PathwayBrowser/#/R-SSC-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Sus scrofa 37671 R-XTR-166726 https://reactome.org/PathwayBrowser/#/R-XTR-166726 Activation of MASPs IEA Xenopus tropicalis 37671 R-XTR-166753 https://reactome.org/PathwayBrowser/#/R-XTR-166753 Conversion of C4 into C4a and C4b IEA Xenopus tropicalis 37671 R-XTR-166792 https://reactome.org/PathwayBrowser/#/R-XTR-166792 Conversion of C2 into C2a and C2b IEA Xenopus tropicalis 37671 R-XTR-2855054 https://reactome.org/PathwayBrowser/#/R-XTR-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Xenopus tropicalis 3768 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 3768 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 3768 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 3768 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 3768 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 3768 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 3768 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 3768 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 3768 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 3768 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 3768 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 3768 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 3768 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 3768 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 3768 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 3768 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 3768 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 3768 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 3768 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 3768 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 3768 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 3768 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 3768 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 3768 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 3768 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 3768 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 3768 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 3768 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 3768 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 3768 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 3768 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 3768 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 3768 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 3768 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 3768 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 3768 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 3768 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 3768 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 3768 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 3768 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 3768 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 3768 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 37739 R-BTA-8857662 https://reactome.org/PathwayBrowser/#/R-BTA-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Bos taurus 37739 R-CEL-8857662 https://reactome.org/PathwayBrowser/#/R-CEL-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Caenorhabditis elegans 37739 R-CFA-8857662 https://reactome.org/PathwayBrowser/#/R-CFA-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Canis familiaris 37739 R-DME-8857662 https://reactome.org/PathwayBrowser/#/R-DME-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Drosophila melanogaster 37739 R-GGA-8857662 https://reactome.org/PathwayBrowser/#/R-GGA-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Gallus gallus 37739 R-HSA-8857662 https://reactome.org/PathwayBrowser/#/R-HSA-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane TAS Homo sapiens 37739 R-MMU-8857662 https://reactome.org/PathwayBrowser/#/R-MMU-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Mus musculus 37739 R-RNO-8857662 https://reactome.org/PathwayBrowser/#/R-RNO-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Rattus norvegicus 37739 R-SSC-8857662 https://reactome.org/PathwayBrowser/#/R-SSC-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Sus scrofa 37894 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 37894 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 37894 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 37894 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 37894 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 37894 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 37894 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 37894 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 37894 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 37941 R-BTA-417829 https://reactome.org/PathwayBrowser/#/R-BTA-417829 P2RY12 binds ADP IEA Bos taurus 37941 R-BTA-9611277 https://reactome.org/PathwayBrowser/#/R-BTA-9611277 P2RY12 binds P2RY12 antagonists IEA Bos taurus 37941 R-CFA-417829 https://reactome.org/PathwayBrowser/#/R-CFA-417829 P2RY12 binds ADP IEA Canis familiaris 37941 R-CFA-9611277 https://reactome.org/PathwayBrowser/#/R-CFA-9611277 P2RY12 binds P2RY12 antagonists IEA Canis familiaris 37941 R-DRE-417829 https://reactome.org/PathwayBrowser/#/R-DRE-417829 P2RY12 binds ADP IEA Danio rerio 37941 R-DRE-9611277 https://reactome.org/PathwayBrowser/#/R-DRE-9611277 P2RY12 binds P2RY12 antagonists IEA Danio rerio 37941 R-HSA-417829 https://reactome.org/PathwayBrowser/#/R-HSA-417829 P2RY12 binds ADP TAS Homo sapiens 37941 R-HSA-9611277 https://reactome.org/PathwayBrowser/#/R-HSA-9611277 P2RY12 binds P2RY12 antagonists TAS Homo sapiens 37941 R-MMU-417829 https://reactome.org/PathwayBrowser/#/R-MMU-417829 P2RY12 binds ADP IEA Mus musculus 37941 R-MMU-9611277 https://reactome.org/PathwayBrowser/#/R-MMU-9611277 P2RY12 binds P2RY12 antagonists IEA Mus musculus 37941 R-RNO-417829 https://reactome.org/PathwayBrowser/#/R-RNO-417829 P2RY12 binds ADP IEA Rattus norvegicus 37941 R-RNO-9611277 https://reactome.org/PathwayBrowser/#/R-RNO-9611277 P2RY12 binds P2RY12 antagonists IEA Rattus norvegicus 37941 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa 37941 R-SSC-9611277 https://reactome.org/PathwayBrowser/#/R-SSC-9611277 P2RY12 binds P2RY12 antagonists IEA Sus scrofa 37941 R-XTR-417829 https://reactome.org/PathwayBrowser/#/R-XTR-417829 P2RY12 binds ADP IEA Xenopus tropicalis 37941 R-XTR-9611277 https://reactome.org/PathwayBrowser/#/R-XTR-9611277 P2RY12 binds P2RY12 antagonists IEA Xenopus tropicalis 37946 R-BTA-159358 https://reactome.org/PathwayBrowser/#/R-BTA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Bos taurus 37946 R-CFA-159358 https://reactome.org/PathwayBrowser/#/R-CFA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Canis familiaris 37946 R-DME-159358 https://reactome.org/PathwayBrowser/#/R-DME-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Drosophila melanogaster 37946 R-DRE-159358 https://reactome.org/PathwayBrowser/#/R-DRE-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Danio rerio 37946 R-GGA-159358 https://reactome.org/PathwayBrowser/#/R-GGA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Gallus gallus 37946 R-HSA-159358 https://reactome.org/PathwayBrowser/#/R-HSA-159358 SULT1A3,4 dimers sulfate DA to DAOS TAS Homo sapiens 37946 R-MMU-159358 https://reactome.org/PathwayBrowser/#/R-MMU-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Mus musculus 37946 R-RNO-159358 https://reactome.org/PathwayBrowser/#/R-RNO-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Rattus norvegicus 37946 R-SSC-159358 https://reactome.org/PathwayBrowser/#/R-SSC-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Sus scrofa 37946 R-XTR-159358 https://reactome.org/PathwayBrowser/#/R-XTR-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Xenopus tropicalis 38290 R-BTA-1234159 https://reactome.org/PathwayBrowser/#/R-BTA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Bos taurus 38290 R-BTA-1234163 https://reactome.org/PathwayBrowser/#/R-BTA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Bos taurus 38290 R-BTA-1234164 https://reactome.org/PathwayBrowser/#/R-BTA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Bos taurus 38290 R-BTA-1234165 https://reactome.org/PathwayBrowser/#/R-BTA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Bos taurus 38290 R-BTA-1234173 https://reactome.org/PathwayBrowser/#/R-BTA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Bos taurus 38290 R-BTA-1234177 https://reactome.org/PathwayBrowser/#/R-BTA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Bos taurus 38290 R-BTA-1234181 https://reactome.org/PathwayBrowser/#/R-BTA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Bos taurus 38290 R-BTA-1234183 https://reactome.org/PathwayBrowser/#/R-BTA-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Bos taurus 38290 R-BTA-198813 https://reactome.org/PathwayBrowser/#/R-BTA-198813 GSTO dimers reduce DeHA to AscH- IEA Bos taurus 38290 R-BTA-198845 https://reactome.org/PathwayBrowser/#/R-BTA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Bos taurus 38290 R-BTA-198870 https://reactome.org/PathwayBrowser/#/R-BTA-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Bos taurus 38290 R-BTA-209891 https://reactome.org/PathwayBrowser/#/R-BTA-209891 Dopamine is oxidised to noradrenaline IEA Bos taurus 38290 R-BTA-71163 https://reactome.org/PathwayBrowser/#/R-BTA-71163 HPD dioxygenates HPP IEA Bos taurus 38290 R-BTA-71241 https://reactome.org/PathwayBrowser/#/R-BTA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Bos taurus 38290 R-BTA-71261 https://reactome.org/PathwayBrowser/#/R-BTA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Bos taurus 38290 R-CEL-1234159 https://reactome.org/PathwayBrowser/#/R-CEL-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Caenorhabditis elegans 38290 R-CEL-1234163 https://reactome.org/PathwayBrowser/#/R-CEL-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Caenorhabditis elegans 38290 R-CEL-1234165 https://reactome.org/PathwayBrowser/#/R-CEL-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 38290 R-CEL-1234173 https://reactome.org/PathwayBrowser/#/R-CEL-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 38290 R-CEL-1234177 https://reactome.org/PathwayBrowser/#/R-CEL-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 38290 R-CEL-1234181 https://reactome.org/PathwayBrowser/#/R-CEL-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 38290 R-CEL-1234183 https://reactome.org/PathwayBrowser/#/R-CEL-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Caenorhabditis elegans 38290 R-CEL-198813 https://reactome.org/PathwayBrowser/#/R-CEL-198813 GSTO dimers reduce DeHA to AscH- IEA Caenorhabditis elegans 38290 R-CEL-198845 https://reactome.org/PathwayBrowser/#/R-CEL-198845 CYB5A:heme reduces Asc.- to AscH- IEA Caenorhabditis elegans 38290 R-CEL-198870 https://reactome.org/PathwayBrowser/#/R-CEL-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 38290 R-CEL-71163 https://reactome.org/PathwayBrowser/#/R-CEL-71163 HPD dioxygenates HPP IEA Caenorhabditis elegans 38290 R-CEL-71241 https://reactome.org/PathwayBrowser/#/R-CEL-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Caenorhabditis elegans 38290 R-CEL-71261 https://reactome.org/PathwayBrowser/#/R-CEL-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Caenorhabditis elegans 38290 R-CFA-1234159 https://reactome.org/PathwayBrowser/#/R-CFA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Canis familiaris 38290 R-CFA-1234163 https://reactome.org/PathwayBrowser/#/R-CFA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Canis familiaris 38290 R-CFA-1234164 https://reactome.org/PathwayBrowser/#/R-CFA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Canis familiaris 38290 R-CFA-1234165 https://reactome.org/PathwayBrowser/#/R-CFA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 38290 R-CFA-1234173 https://reactome.org/PathwayBrowser/#/R-CFA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 38290 R-CFA-1234177 https://reactome.org/PathwayBrowser/#/R-CFA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 38290 R-CFA-1234181 https://reactome.org/PathwayBrowser/#/R-CFA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 38290 R-CFA-1234183 https://reactome.org/PathwayBrowser/#/R-CFA-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Canis familiaris 38290 R-CFA-198813 https://reactome.org/PathwayBrowser/#/R-CFA-198813 GSTO dimers reduce DeHA to AscH- IEA Canis familiaris 38290 R-CFA-198845 https://reactome.org/PathwayBrowser/#/R-CFA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Canis familiaris 38290 R-CFA-198870 https://reactome.org/PathwayBrowser/#/R-CFA-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 38290 R-CFA-209891 https://reactome.org/PathwayBrowser/#/R-CFA-209891 Dopamine is oxidised to noradrenaline IEA Canis familiaris 38290 R-CFA-71163 https://reactome.org/PathwayBrowser/#/R-CFA-71163 HPD dioxygenates HPP IEA Canis familiaris 38290 R-CFA-71241 https://reactome.org/PathwayBrowser/#/R-CFA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Canis familiaris 38290 R-CFA-71261 https://reactome.org/PathwayBrowser/#/R-CFA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Canis familiaris 38290 R-DDI-198845 https://reactome.org/PathwayBrowser/#/R-DDI-198845 CYB5A:heme reduces Asc.- to AscH- IEA Dictyostelium discoideum 38290 R-DDI-71163 https://reactome.org/PathwayBrowser/#/R-DDI-71163 HPD dioxygenates HPP IEA Dictyostelium discoideum 38290 R-DME-1234159 https://reactome.org/PathwayBrowser/#/R-DME-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Drosophila melanogaster 38290 R-DME-1234163 https://reactome.org/PathwayBrowser/#/R-DME-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Drosophila melanogaster 38290 R-DME-1234165 https://reactome.org/PathwayBrowser/#/R-DME-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 38290 R-DME-1234173 https://reactome.org/PathwayBrowser/#/R-DME-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 38290 R-DME-1234177 https://reactome.org/PathwayBrowser/#/R-DME-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 38290 R-DME-1234181 https://reactome.org/PathwayBrowser/#/R-DME-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 38290 R-DME-1234183 https://reactome.org/PathwayBrowser/#/R-DME-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Drosophila melanogaster 38290 R-DME-198813 https://reactome.org/PathwayBrowser/#/R-DME-198813 GSTO dimers reduce DeHA to AscH- IEA Drosophila melanogaster 38290 R-DME-198845 https://reactome.org/PathwayBrowser/#/R-DME-198845 CYB5A:heme reduces Asc.- to AscH- IEA Drosophila melanogaster 38290 R-DME-198870 https://reactome.org/PathwayBrowser/#/R-DME-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 38290 R-DME-209891 https://reactome.org/PathwayBrowser/#/R-DME-209891 Dopamine is oxidised to noradrenaline IEA Drosophila melanogaster 38290 R-DME-71163 https://reactome.org/PathwayBrowser/#/R-DME-71163 HPD dioxygenates HPP IEA Drosophila melanogaster 38290 R-DME-71241 https://reactome.org/PathwayBrowser/#/R-DME-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Drosophila melanogaster 38290 R-DME-71261 https://reactome.org/PathwayBrowser/#/R-DME-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Drosophila melanogaster 38290 R-DRE-1234164 https://reactome.org/PathwayBrowser/#/R-DRE-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Danio rerio 38290 R-DRE-1234165 https://reactome.org/PathwayBrowser/#/R-DRE-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Danio rerio 38290 R-DRE-1234181 https://reactome.org/PathwayBrowser/#/R-DRE-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Danio rerio 38290 R-DRE-198813 https://reactome.org/PathwayBrowser/#/R-DRE-198813 GSTO dimers reduce DeHA to AscH- IEA Danio rerio 38290 R-DRE-198845 https://reactome.org/PathwayBrowser/#/R-DRE-198845 CYB5A:heme reduces Asc.- to AscH- IEA Danio rerio 38290 R-DRE-209891 https://reactome.org/PathwayBrowser/#/R-DRE-209891 Dopamine is oxidised to noradrenaline IEA Danio rerio 38290 R-DRE-71163 https://reactome.org/PathwayBrowser/#/R-DRE-71163 HPD dioxygenates HPP IEA Danio rerio 38290 R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio 38290 R-GGA-1234163 https://reactome.org/PathwayBrowser/#/R-GGA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Gallus gallus 38290 R-GGA-1234164 https://reactome.org/PathwayBrowser/#/R-GGA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Gallus gallus 38290 R-GGA-1234165 https://reactome.org/PathwayBrowser/#/R-GGA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 38290 R-GGA-1234173 https://reactome.org/PathwayBrowser/#/R-GGA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 38290 R-GGA-1234177 https://reactome.org/PathwayBrowser/#/R-GGA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 38290 R-GGA-1234181 https://reactome.org/PathwayBrowser/#/R-GGA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 38290 R-GGA-1234183 https://reactome.org/PathwayBrowser/#/R-GGA-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Gallus gallus 38290 R-GGA-198813 https://reactome.org/PathwayBrowser/#/R-GGA-198813 GSTO dimers reduce DeHA to AscH- IEA Gallus gallus 38290 R-GGA-198845 https://reactome.org/PathwayBrowser/#/R-GGA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Gallus gallus 38290 R-GGA-198870 https://reactome.org/PathwayBrowser/#/R-GGA-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 38290 R-GGA-209891 https://reactome.org/PathwayBrowser/#/R-GGA-209891 Dopamine is oxidised to noradrenaline IEA Gallus gallus 38290 R-GGA-71163 https://reactome.org/PathwayBrowser/#/R-GGA-71163 HPD dioxygenates HPP IEA Gallus gallus 38290 R-GGA-71241 https://reactome.org/PathwayBrowser/#/R-GGA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Gallus gallus 38290 R-GGA-71261 https://reactome.org/PathwayBrowser/#/R-GGA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Gallus gallus 38290 R-HSA-1234159 https://reactome.org/PathwayBrowser/#/R-HSA-1234159 Proteasome proteolyzes ub-HIF-alpha TAS Homo sapiens 38290 R-HSA-1234163 https://reactome.org/PathwayBrowser/#/R-HSA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha TAS Homo sapiens 38290 R-HSA-1234164 https://reactome.org/PathwayBrowser/#/R-HSA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) TAS Homo sapiens 38290 R-HSA-1234165 https://reactome.org/PathwayBrowser/#/R-HSA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 38290 R-HSA-1234166 https://reactome.org/PathwayBrowser/#/R-HSA-1234166 Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 38290 R-HSA-1234173 https://reactome.org/PathwayBrowser/#/R-HSA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 38290 R-HSA-1234177 https://reactome.org/PathwayBrowser/#/R-HSA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 38290 R-HSA-1234179 https://reactome.org/PathwayBrowser/#/R-HSA-1234179 Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 38290 R-HSA-1234181 https://reactome.org/PathwayBrowser/#/R-HSA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 38290 R-HSA-1234183 https://reactome.org/PathwayBrowser/#/R-HSA-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha TAS Homo sapiens 38290 R-HSA-1497855 https://reactome.org/PathwayBrowser/#/R-HSA-1497855 Ascorbate can reduce the BH3 radical back to BH4 TAS Homo sapiens 38290 R-HSA-198813 https://reactome.org/PathwayBrowser/#/R-HSA-198813 GSTO dimers reduce DeHA to AscH- TAS Homo sapiens 38290 R-HSA-198845 https://reactome.org/PathwayBrowser/#/R-HSA-198845 CYB5A:heme reduces Asc.- to AscH- TAS Homo sapiens 38290 R-HSA-198870 https://reactome.org/PathwayBrowser/#/R-HSA-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 38290 R-HSA-209891 https://reactome.org/PathwayBrowser/#/R-HSA-209891 Dopamine is oxidised to noradrenaline TAS Homo sapiens 38290 R-HSA-5221014 https://reactome.org/PathwayBrowser/#/R-HSA-5221014 TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine IEA Homo sapiens 38290 R-HSA-71163 https://reactome.org/PathwayBrowser/#/R-HSA-71163 HPD dioxygenates HPP TAS Homo sapiens 38290 R-HSA-71241 https://reactome.org/PathwayBrowser/#/R-HSA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA TAS Homo sapiens 38290 R-HSA-71261 https://reactome.org/PathwayBrowser/#/R-HSA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA TAS Homo sapiens 38290 R-HSA-9640302 https://reactome.org/PathwayBrowser/#/R-HSA-9640302 Asc.- radical dissociates to AscH- and DeHA TAS Homo sapiens 38290 R-MMU-1234159 https://reactome.org/PathwayBrowser/#/R-MMU-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Mus musculus 38290 R-MMU-1234163 https://reactome.org/PathwayBrowser/#/R-MMU-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Mus musculus 38290 R-MMU-1234164 https://reactome.org/PathwayBrowser/#/R-MMU-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Mus musculus 38290 R-MMU-1234165 https://reactome.org/PathwayBrowser/#/R-MMU-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Mus musculus 38290 R-MMU-1234173 https://reactome.org/PathwayBrowser/#/R-MMU-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Mus musculus 38290 R-MMU-1234177 https://reactome.org/PathwayBrowser/#/R-MMU-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Mus musculus 38290 R-MMU-1234181 https://reactome.org/PathwayBrowser/#/R-MMU-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Mus musculus 38290 R-MMU-1234183 https://reactome.org/PathwayBrowser/#/R-MMU-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Mus musculus 38290 R-MMU-198813 https://reactome.org/PathwayBrowser/#/R-MMU-198813 GSTO dimers reduce DeHA to AscH- IEA Mus musculus 38290 R-MMU-198845 https://reactome.org/PathwayBrowser/#/R-MMU-198845 CYB5A:heme reduces Asc.- to AscH- IEA Mus musculus 38290 R-MMU-198870 https://reactome.org/PathwayBrowser/#/R-MMU-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Mus musculus 38290 R-MMU-209891 https://reactome.org/PathwayBrowser/#/R-MMU-209891 Dopamine is oxidised to noradrenaline IEA Mus musculus 38290 R-MMU-5220944 https://reactome.org/PathwayBrowser/#/R-MMU-5220944 Tet1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine TAS Mus musculus 38290 R-MMU-71163 https://reactome.org/PathwayBrowser/#/R-MMU-71163 HPD dioxygenates HPP IEA Mus musculus 38290 R-MMU-71241 https://reactome.org/PathwayBrowser/#/R-MMU-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Mus musculus 38290 R-MMU-71261 https://reactome.org/PathwayBrowser/#/R-MMU-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Mus musculus 38290 R-RNO-1234159 https://reactome.org/PathwayBrowser/#/R-RNO-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Rattus norvegicus 38290 R-RNO-1234163 https://reactome.org/PathwayBrowser/#/R-RNO-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Rattus norvegicus 38290 R-RNO-1234164 https://reactome.org/PathwayBrowser/#/R-RNO-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Rattus norvegicus 38290 R-RNO-1234165 https://reactome.org/PathwayBrowser/#/R-RNO-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 38290 R-RNO-1234173 https://reactome.org/PathwayBrowser/#/R-RNO-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 38290 R-RNO-1234177 https://reactome.org/PathwayBrowser/#/R-RNO-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 38290 R-RNO-1234181 https://reactome.org/PathwayBrowser/#/R-RNO-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 38290 R-RNO-1234183 https://reactome.org/PathwayBrowser/#/R-RNO-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Rattus norvegicus 38290 R-RNO-198813 https://reactome.org/PathwayBrowser/#/R-RNO-198813 GSTO dimers reduce DeHA to AscH- IEA Rattus norvegicus 38290 R-RNO-198845 https://reactome.org/PathwayBrowser/#/R-RNO-198845 CYB5A:heme reduces Asc.- to AscH- IEA Rattus norvegicus 38290 R-RNO-198870 https://reactome.org/PathwayBrowser/#/R-RNO-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 38290 R-RNO-209891 https://reactome.org/PathwayBrowser/#/R-RNO-209891 Dopamine is oxidised to noradrenaline IEA Rattus norvegicus 38290 R-RNO-71163 https://reactome.org/PathwayBrowser/#/R-RNO-71163 HPD dioxygenates HPP IEA Rattus norvegicus 38290 R-RNO-71241 https://reactome.org/PathwayBrowser/#/R-RNO-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Rattus norvegicus 38290 R-RNO-71261 https://reactome.org/PathwayBrowser/#/R-RNO-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Rattus norvegicus 38290 R-SCE-198845 https://reactome.org/PathwayBrowser/#/R-SCE-198845 CYB5A:heme reduces Asc.- to AscH- IEA Saccharomyces cerevisiae 38290 R-SCE-71261 https://reactome.org/PathwayBrowser/#/R-SCE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Saccharomyces cerevisiae 38290 R-SPO-198845 https://reactome.org/PathwayBrowser/#/R-SPO-198845 CYB5A:heme reduces Asc.- to AscH- IEA Schizosaccharomyces pombe 38290 R-SSC-1234159 https://reactome.org/PathwayBrowser/#/R-SSC-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Sus scrofa 38290 R-SSC-1234163 https://reactome.org/PathwayBrowser/#/R-SSC-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Sus scrofa 38290 R-SSC-1234164 https://reactome.org/PathwayBrowser/#/R-SSC-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Sus scrofa 38290 R-SSC-1234165 https://reactome.org/PathwayBrowser/#/R-SSC-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 38290 R-SSC-1234173 https://reactome.org/PathwayBrowser/#/R-SSC-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Sus scrofa 38290 R-SSC-1234177 https://reactome.org/PathwayBrowser/#/R-SSC-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 38290 R-SSC-1234181 https://reactome.org/PathwayBrowser/#/R-SSC-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Sus scrofa 38290 R-SSC-1234183 https://reactome.org/PathwayBrowser/#/R-SSC-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Sus scrofa 38290 R-SSC-198813 https://reactome.org/PathwayBrowser/#/R-SSC-198813 GSTO dimers reduce DeHA to AscH- IEA Sus scrofa 38290 R-SSC-198845 https://reactome.org/PathwayBrowser/#/R-SSC-198845 CYB5A:heme reduces Asc.- to AscH- IEA Sus scrofa 38290 R-SSC-198870 https://reactome.org/PathwayBrowser/#/R-SSC-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 38290 R-SSC-209891 https://reactome.org/PathwayBrowser/#/R-SSC-209891 Dopamine is oxidised to noradrenaline IEA Sus scrofa 38290 R-SSC-71163 https://reactome.org/PathwayBrowser/#/R-SSC-71163 HPD dioxygenates HPP IEA Sus scrofa 38290 R-SSC-71241 https://reactome.org/PathwayBrowser/#/R-SSC-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Sus scrofa 38290 R-SSC-71261 https://reactome.org/PathwayBrowser/#/R-SSC-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Sus scrofa 38290 R-XTR-1234163 https://reactome.org/PathwayBrowser/#/R-XTR-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Xenopus tropicalis 38290 R-XTR-1234164 https://reactome.org/PathwayBrowser/#/R-XTR-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Xenopus tropicalis 38290 R-XTR-1234165 https://reactome.org/PathwayBrowser/#/R-XTR-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 38290 R-XTR-1234173 https://reactome.org/PathwayBrowser/#/R-XTR-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Xenopus tropicalis 38290 R-XTR-1234177 https://reactome.org/PathwayBrowser/#/R-XTR-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 38290 R-XTR-1234181 https://reactome.org/PathwayBrowser/#/R-XTR-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Xenopus tropicalis 38290 R-XTR-1234183 https://reactome.org/PathwayBrowser/#/R-XTR-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Xenopus tropicalis 38290 R-XTR-198813 https://reactome.org/PathwayBrowser/#/R-XTR-198813 GSTO dimers reduce DeHA to AscH- IEA Xenopus tropicalis 38290 R-XTR-198845 https://reactome.org/PathwayBrowser/#/R-XTR-198845 CYB5A:heme reduces Asc.- to AscH- IEA Xenopus tropicalis 38290 R-XTR-198870 https://reactome.org/PathwayBrowser/#/R-XTR-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 38290 R-XTR-209891 https://reactome.org/PathwayBrowser/#/R-XTR-209891 Dopamine is oxidised to noradrenaline IEA Xenopus tropicalis 38290 R-XTR-71163 https://reactome.org/PathwayBrowser/#/R-XTR-71163 HPD dioxygenates HPP IEA Xenopus tropicalis 38290 R-XTR-71241 https://reactome.org/PathwayBrowser/#/R-XTR-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Xenopus tropicalis 38290 R-XTR-71261 https://reactome.org/PathwayBrowser/#/R-XTR-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Xenopus tropicalis 38573 R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 38573 R-BTA-164651 https://reactome.org/PathwayBrowser/#/R-BTA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Bos taurus 38573 R-BTA-3341294 https://reactome.org/PathwayBrowser/#/R-BTA-3341294 Superoxide reduces cytochrome c IEA Bos taurus 38573 R-CEL-164651 https://reactome.org/PathwayBrowser/#/R-CEL-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Caenorhabditis elegans 38573 R-CEL-3341294 https://reactome.org/PathwayBrowser/#/R-CEL-3341294 Superoxide reduces cytochrome c IEA Caenorhabditis elegans 38573 R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 38573 R-CFA-3341294 https://reactome.org/PathwayBrowser/#/R-CFA-3341294 Superoxide reduces cytochrome c IEA Canis familiaris 38573 R-DDI-164651 https://reactome.org/PathwayBrowser/#/R-DDI-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Dictyostelium discoideum 38573 R-DDI-3341294 https://reactome.org/PathwayBrowser/#/R-DDI-3341294 Superoxide reduces cytochrome c IEA Dictyostelium discoideum 38573 R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 38573 R-DME-164651 https://reactome.org/PathwayBrowser/#/R-DME-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Drosophila melanogaster 38573 R-DME-3341294 https://reactome.org/PathwayBrowser/#/R-DME-3341294 Superoxide reduces cytochrome c IEA Drosophila melanogaster 38573 R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 38573 R-DRE-164651 https://reactome.org/PathwayBrowser/#/R-DRE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Danio rerio 38573 R-DRE-3341294 https://reactome.org/PathwayBrowser/#/R-DRE-3341294 Superoxide reduces cytochrome c IEA Danio rerio 38573 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 38573 R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus 38573 R-GGA-3341294 https://reactome.org/PathwayBrowser/#/R-GGA-3341294 Superoxide reduces cytochrome c IEA Gallus gallus 38573 R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 38573 R-HSA-164651 https://reactome.org/PathwayBrowser/#/R-HSA-164651 Electron transfer from ubiquinol to cytochrome c of complex III TAS Homo sapiens 38573 R-HSA-3341294 https://reactome.org/PathwayBrowser/#/R-HSA-3341294 Superoxide reduces cytochrome c TAS Homo sapiens 38573 R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 38573 R-MMU-164651 https://reactome.org/PathwayBrowser/#/R-MMU-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Mus musculus 38573 R-MMU-3341294 https://reactome.org/PathwayBrowser/#/R-MMU-3341294 Superoxide reduces cytochrome c IEA Mus musculus 38573 R-PFA-3341294 https://reactome.org/PathwayBrowser/#/R-PFA-3341294 Superoxide reduces cytochrome c IEA Plasmodium falciparum 38573 R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 38573 R-RNO-164651 https://reactome.org/PathwayBrowser/#/R-RNO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Rattus norvegicus 38573 R-RNO-3341294 https://reactome.org/PathwayBrowser/#/R-RNO-3341294 Superoxide reduces cytochrome c IEA Rattus norvegicus 38573 R-SCE-164651 https://reactome.org/PathwayBrowser/#/R-SCE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Saccharomyces cerevisiae 38573 R-SCE-3341294 https://reactome.org/PathwayBrowser/#/R-SCE-3341294 Superoxide reduces cytochrome c IEA Saccharomyces cerevisiae 38573 R-SPO-164651 https://reactome.org/PathwayBrowser/#/R-SPO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Schizosaccharomyces pombe 38573 R-SPO-3341294 https://reactome.org/PathwayBrowser/#/R-SPO-3341294 Superoxide reduces cytochrome c IEA Schizosaccharomyces pombe 38573 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa 38573 R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa 38573 R-SSC-3341294 https://reactome.org/PathwayBrowser/#/R-SSC-3341294 Superoxide reduces cytochrome c IEA Sus scrofa 38573 R-XTR-163214 https://reactome.org/PathwayBrowser/#/R-XTR-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Xenopus tropicalis 38573 R-XTR-3341294 https://reactome.org/PathwayBrowser/#/R-XTR-3341294 Superoxide reduces cytochrome c IEA Xenopus tropicalis 38574 R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 38574 R-BTA-164651 https://reactome.org/PathwayBrowser/#/R-BTA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Bos taurus 38574 R-BTA-3341294 https://reactome.org/PathwayBrowser/#/R-BTA-3341294 Superoxide reduces cytochrome c IEA Bos taurus 38574 R-CEL-164651 https://reactome.org/PathwayBrowser/#/R-CEL-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Caenorhabditis elegans 38574 R-CEL-3341294 https://reactome.org/PathwayBrowser/#/R-CEL-3341294 Superoxide reduces cytochrome c IEA Caenorhabditis elegans 38574 R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 38574 R-CFA-3341294 https://reactome.org/PathwayBrowser/#/R-CFA-3341294 Superoxide reduces cytochrome c IEA Canis familiaris 38574 R-DDI-164651 https://reactome.org/PathwayBrowser/#/R-DDI-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Dictyostelium discoideum 38574 R-DDI-3341294 https://reactome.org/PathwayBrowser/#/R-DDI-3341294 Superoxide reduces cytochrome c IEA Dictyostelium discoideum 38574 R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 38574 R-DME-164651 https://reactome.org/PathwayBrowser/#/R-DME-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Drosophila melanogaster 38574 R-DME-3341294 https://reactome.org/PathwayBrowser/#/R-DME-3341294 Superoxide reduces cytochrome c IEA Drosophila melanogaster 38574 R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 38574 R-DRE-164651 https://reactome.org/PathwayBrowser/#/R-DRE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Danio rerio 38574 R-DRE-3341294 https://reactome.org/PathwayBrowser/#/R-DRE-3341294 Superoxide reduces cytochrome c IEA Danio rerio 38574 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 38574 R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus 38574 R-GGA-3341294 https://reactome.org/PathwayBrowser/#/R-GGA-3341294 Superoxide reduces cytochrome c IEA Gallus gallus 38574 R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 38574 R-HSA-164651 https://reactome.org/PathwayBrowser/#/R-HSA-164651 Electron transfer from ubiquinol to cytochrome c of complex III TAS Homo sapiens 38574 R-HSA-3341294 https://reactome.org/PathwayBrowser/#/R-HSA-3341294 Superoxide reduces cytochrome c TAS Homo sapiens 38574 R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 38574 R-MMU-164651 https://reactome.org/PathwayBrowser/#/R-MMU-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Mus musculus 38574 R-MMU-3341294 https://reactome.org/PathwayBrowser/#/R-MMU-3341294 Superoxide reduces cytochrome c IEA Mus musculus 38574 R-PFA-3341294 https://reactome.org/PathwayBrowser/#/R-PFA-3341294 Superoxide reduces cytochrome c IEA Plasmodium falciparum 38574 R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 38574 R-RNO-164651 https://reactome.org/PathwayBrowser/#/R-RNO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Rattus norvegicus 38574 R-RNO-3341294 https://reactome.org/PathwayBrowser/#/R-RNO-3341294 Superoxide reduces cytochrome c IEA Rattus norvegicus 38574 R-SCE-164651 https://reactome.org/PathwayBrowser/#/R-SCE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Saccharomyces cerevisiae 38574 R-SCE-3341294 https://reactome.org/PathwayBrowser/#/R-SCE-3341294 Superoxide reduces cytochrome c IEA Saccharomyces cerevisiae 38574 R-SPO-164651 https://reactome.org/PathwayBrowser/#/R-SPO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Schizosaccharomyces pombe 38574 R-SPO-3341294 https://reactome.org/PathwayBrowser/#/R-SPO-3341294 Superoxide reduces cytochrome c IEA Schizosaccharomyces pombe 38574 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa 38574 R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa 38574 R-SSC-3341294 https://reactome.org/PathwayBrowser/#/R-SSC-3341294 Superoxide reduces cytochrome c IEA Sus scrofa 38574 R-XTR-163214 https://reactome.org/PathwayBrowser/#/R-XTR-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Xenopus tropicalis 38574 R-XTR-3341294 https://reactome.org/PathwayBrowser/#/R-XTR-3341294 Superoxide reduces cytochrome c IEA Xenopus tropicalis 38635 R-BTA-110248 https://reactome.org/PathwayBrowser/#/R-BTA-110248 Cleavage of 3-methyladenine by MPG glycosylase IEA Bos taurus 38635 R-CFA-110248 https://reactome.org/PathwayBrowser/#/R-CFA-110248 Cleavage of 3-methyladenine by MPG glycosylase IEA Canis familiaris 38635 R-DRE-110248 https://reactome.org/PathwayBrowser/#/R-DRE-110248 Cleavage of 3-methyladenine by MPG glycosylase IEA Danio rerio 38635 R-GGA-110248 https://reactome.org/PathwayBrowser/#/R-GGA-110248 Cleavage of 3-methyladenine by MPG glycosylase IEA Gallus gallus 38635 R-HSA-110248 https://reactome.org/PathwayBrowser/#/R-HSA-110248 Cleavage of 3-methyladenine by MPG glycosylase TAS Homo sapiens 38635 R-MMU-110248 https://reactome.org/PathwayBrowser/#/R-MMU-110248 Cleavage of 3-methyladenine by MPG glycosylase IEA Mus musculus 38635 R-PFA-110248 https://reactome.org/PathwayBrowser/#/R-PFA-110248 Cleavage of 3-methyladenine by MPG glycosylase IEA Plasmodium falciparum 38635 R-RNO-110248 https://reactome.org/PathwayBrowser/#/R-RNO-110248 Cleavage of 3-methyladenine by MPG glycosylase IEA Rattus norvegicus 38635 R-SSC-110248 https://reactome.org/PathwayBrowser/#/R-SSC-110248 Cleavage of 3-methyladenine by MPG glycosylase IEA Sus scrofa 38635 R-XTR-110248 https://reactome.org/PathwayBrowser/#/R-XTR-110248 Cleavage of 3-methyladenine by MPG glycosylase IEA Xenopus tropicalis 38927 R-HSA-1220611 https://reactome.org/PathwayBrowser/#/R-HSA-1220611 Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors TAS Homo sapiens 38927 R-HSA-1225978 https://reactome.org/PathwayBrowser/#/R-HSA-1225978 Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers TAS Homo sapiens 3941 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 3941 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 3941 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 3941 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 3941 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 3941 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 3941 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 3941 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 3941 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 3941 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 3941 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 3941 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 3941 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 3941 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 3941 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 3941 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 3941 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 3941 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 3941 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 3941 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 3941 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 3941 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 3941 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 3941 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 3941 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 3941 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 3941 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 3941 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 3941 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 3941 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 3941 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 3941 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 3941 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 3941 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 3941 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 3941 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 3941 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 3941 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 3941 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 3941 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 3941 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 3941 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 3944 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 3944 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 3944 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 3944 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 3944 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 3944 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 3944 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 3944 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 3944 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 3944 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 3944 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 3944 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 3944 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 3944 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 3944 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 3944 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 3944 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 3944 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 3944 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 3944 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 3944 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 3944 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 3944 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 3944 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 3944 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 3944 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 3944 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 3944 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 3944 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 3944 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 3944 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 3944 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 3944 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 3944 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 3944 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 3944 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 3944 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 3944 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 3944 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 3944 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 3944 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 3944 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 39567 R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 39567 R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 39567 R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 39567 R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 39567 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 39567 R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 39567 R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 39567 R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 4026 R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 4026 R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 4026 R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 4026 R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 4026 R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 4026 R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 4026 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 4026 R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 4026 R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 4026 R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 4026 R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa 4026 R-XTR-211991 https://reactome.org/PathwayBrowser/#/R-XTR-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Xenopus tropicalis 40277 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 40277 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 40277 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 40277 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 40277 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 40277 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 40277 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 40277 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 40277 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 40277 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 40277 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 40277 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 40277 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 40277 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 40277 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 40277 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 40277 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 40277 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 40277 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 40277 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 40277 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 40304 R-BTA-9824732 https://reactome.org/PathwayBrowser/#/R-BTA-9824732 G or G analog binds C-ter TLR7 dimer IEA Bos taurus 40304 R-CFA-9824732 https://reactome.org/PathwayBrowser/#/R-CFA-9824732 G or G analog binds C-ter TLR7 dimer IEA Canis familiaris 40304 R-GGA-9824732 https://reactome.org/PathwayBrowser/#/R-GGA-9824732 G or G analog binds C-ter TLR7 dimer IEA Gallus gallus 40304 R-HSA-9824732 https://reactome.org/PathwayBrowser/#/R-HSA-9824732 G or G analog binds C-ter TLR7 dimer TAS Homo sapiens 40304 R-HSA-9824849 https://reactome.org/PathwayBrowser/#/R-HSA-9824849 G or G analog binds C-ter TLR7 GoF variant TAS Homo sapiens 40304 R-MMU-9824732 https://reactome.org/PathwayBrowser/#/R-MMU-9824732 G or G analog binds C-ter TLR7 dimer IEA Mus musculus 40304 R-RNO-9824732 https://reactome.org/PathwayBrowser/#/R-RNO-9824732 G or G analog binds C-ter TLR7 dimer IEA Rattus norvegicus 40304 R-SSC-9824732 https://reactome.org/PathwayBrowser/#/R-SSC-9824732 G or G analog binds C-ter TLR7 dimer IEA Sus scrofa 40304 R-XTR-9824732 https://reactome.org/PathwayBrowser/#/R-XTR-9824732 G or G analog binds C-ter TLR7 dimer IEA Xenopus tropicalis 40356 R-BTA-166726 https://reactome.org/PathwayBrowser/#/R-BTA-166726 Activation of MASPs IEA Bos taurus 40356 R-BTA-166753 https://reactome.org/PathwayBrowser/#/R-BTA-166753 Conversion of C4 into C4a and C4b IEA Bos taurus 40356 R-BTA-166792 https://reactome.org/PathwayBrowser/#/R-BTA-166792 Conversion of C2 into C2a and C2b IEA Bos taurus 40356 R-BTA-2855054 https://reactome.org/PathwayBrowser/#/R-BTA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Bos taurus 40356 R-BTA-2855125 https://reactome.org/PathwayBrowser/#/R-BTA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Bos taurus 40356 R-CFA-166726 https://reactome.org/PathwayBrowser/#/R-CFA-166726 Activation of MASPs IEA Canis familiaris 40356 R-CFA-166753 https://reactome.org/PathwayBrowser/#/R-CFA-166753 Conversion of C4 into C4a and C4b IEA Canis familiaris 40356 R-CFA-166792 https://reactome.org/PathwayBrowser/#/R-CFA-166792 Conversion of C2 into C2a and C2b IEA Canis familiaris 40356 R-CFA-2855054 https://reactome.org/PathwayBrowser/#/R-CFA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Canis familiaris 40356 R-CFA-2855125 https://reactome.org/PathwayBrowser/#/R-CFA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Canis familiaris 40356 R-GGA-166726 https://reactome.org/PathwayBrowser/#/R-GGA-166726 Activation of MASPs IEA Gallus gallus 40356 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus 40356 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus 40356 R-GGA-2855054 https://reactome.org/PathwayBrowser/#/R-GGA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Gallus gallus 40356 R-GGA-2855125 https://reactome.org/PathwayBrowser/#/R-GGA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Gallus gallus 40356 R-HSA-166726 https://reactome.org/PathwayBrowser/#/R-HSA-166726 Activation of MASPs TAS Homo sapiens 40356 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens 40356 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens 40356 R-HSA-2855054 https://reactome.org/PathwayBrowser/#/R-HSA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface TAS Homo sapiens 40356 R-HSA-2855125 https://reactome.org/PathwayBrowser/#/R-HSA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface TAS Homo sapiens 40356 R-MMU-166726 https://reactome.org/PathwayBrowser/#/R-MMU-166726 Activation of MASPs IEA Mus musculus 40356 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus 40356 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus 40356 R-MMU-2855054 https://reactome.org/PathwayBrowser/#/R-MMU-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Mus musculus 40356 R-MMU-2855125 https://reactome.org/PathwayBrowser/#/R-MMU-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Mus musculus 40356 R-RNO-166726 https://reactome.org/PathwayBrowser/#/R-RNO-166726 Activation of MASPs IEA Rattus norvegicus 40356 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus 40356 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus 40356 R-RNO-2855054 https://reactome.org/PathwayBrowser/#/R-RNO-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Rattus norvegicus 40356 R-RNO-2855125 https://reactome.org/PathwayBrowser/#/R-RNO-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Rattus norvegicus 40356 R-SSC-166726 https://reactome.org/PathwayBrowser/#/R-SSC-166726 Activation of MASPs IEA Sus scrofa 40356 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa 40356 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa 40356 R-SSC-2855054 https://reactome.org/PathwayBrowser/#/R-SSC-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Sus scrofa 40356 R-SSC-2855125 https://reactome.org/PathwayBrowser/#/R-SSC-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Sus scrofa 40356 R-XTR-166726 https://reactome.org/PathwayBrowser/#/R-XTR-166726 Activation of MASPs IEA Xenopus tropicalis 40356 R-XTR-166753 https://reactome.org/PathwayBrowser/#/R-XTR-166753 Conversion of C4 into C4a and C4b IEA Xenopus tropicalis 40356 R-XTR-166792 https://reactome.org/PathwayBrowser/#/R-XTR-166792 Conversion of C2 into C2a and C2b IEA Xenopus tropicalis 40356 R-XTR-2855054 https://reactome.org/PathwayBrowser/#/R-XTR-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Xenopus tropicalis 40356 R-XTR-2855125 https://reactome.org/PathwayBrowser/#/R-XTR-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Xenopus tropicalis 40574 R-BTA-5689000 https://reactome.org/PathwayBrowser/#/R-BTA-5689000 AADAC deacetylates PHEN IEA Bos taurus 40574 R-CEL-5689000 https://reactome.org/PathwayBrowser/#/R-CEL-5689000 AADAC deacetylates PHEN IEA Caenorhabditis elegans 40574 R-CFA-5689000 https://reactome.org/PathwayBrowser/#/R-CFA-5689000 AADAC deacetylates PHEN IEA Canis familiaris 40574 R-DDI-5689000 https://reactome.org/PathwayBrowser/#/R-DDI-5689000 AADAC deacetylates PHEN IEA Dictyostelium discoideum 40574 R-GGA-5689000 https://reactome.org/PathwayBrowser/#/R-GGA-5689000 AADAC deacetylates PHEN IEA Gallus gallus 40574 R-HSA-5689000 https://reactome.org/PathwayBrowser/#/R-HSA-5689000 AADAC deacetylates PHEN TAS Homo sapiens 40574 R-MMU-5689000 https://reactome.org/PathwayBrowser/#/R-MMU-5689000 AADAC deacetylates PHEN IEA Mus musculus 40574 R-RNO-5689000 https://reactome.org/PathwayBrowser/#/R-RNO-5689000 AADAC deacetylates PHEN IEA Rattus norvegicus 40574 R-SPO-5689000 https://reactome.org/PathwayBrowser/#/R-SPO-5689000 AADAC deacetylates PHEN IEA Schizosaccharomyces pombe 40574 R-SSC-5689000 https://reactome.org/PathwayBrowser/#/R-SSC-5689000 AADAC deacetylates PHEN IEA Sus scrofa 40629 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 40629 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 40629 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 40629 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 40629 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 40629 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 40629 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 40629 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 40629 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 40629 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 40629 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 40629 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 40629 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 40629 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 40629 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 40629 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 40629 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 40629 R-HSA-9665278 https://reactome.org/PathwayBrowser/#/R-HSA-9665278 Resistant ERBB2 KD mutants do not bind AEE788 TAS Homo sapiens 40629 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 40629 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 40629 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 40629 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 40629 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 40629 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 408174 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 408174 R-BTA-9611751 https://reactome.org/PathwayBrowser/#/R-BTA-9611751 β1,2-agonists bind ADRB1,2 IEA Bos taurus 408174 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 408174 R-CFA-9611751 https://reactome.org/PathwayBrowser/#/R-CFA-9611751 β1,2-agonists bind ADRB1,2 IEA Canis familiaris 408174 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 408174 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 408174 R-DME-9611751 https://reactome.org/PathwayBrowser/#/R-DME-9611751 β1,2-agonists bind ADRB1,2 IEA Drosophila melanogaster 408174 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 408174 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 408174 R-DRE-9611751 https://reactome.org/PathwayBrowser/#/R-DRE-9611751 β1,2-agonists bind ADRB1,2 IEA Danio rerio 408174 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 408174 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 408174 R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus 408174 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 408174 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 408174 R-HSA-9611751 https://reactome.org/PathwayBrowser/#/R-HSA-9611751 β1,2-agonists bind ADRB1,2 TAS Homo sapiens 408174 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 408174 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 408174 R-MMU-9611751 https://reactome.org/PathwayBrowser/#/R-MMU-9611751 β1,2-agonists bind ADRB1,2 IEA Mus musculus 408174 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 408174 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 408174 R-RNO-9611751 https://reactome.org/PathwayBrowser/#/R-RNO-9611751 β1,2-agonists bind ADRB1,2 IEA Rattus norvegicus 408174 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 408174 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 408174 R-SSC-9611751 https://reactome.org/PathwayBrowser/#/R-SSC-9611751 β1,2-agonists bind ADRB1,2 IEA Sus scrofa 408174 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 408174 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 408174 R-XTR-9611751 https://reactome.org/PathwayBrowser/#/R-XTR-9611751 β1,2-agonists bind ADRB1,2 IEA Xenopus tropicalis 408174 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 41001 R-BTA-5693691 https://reactome.org/PathwayBrowser/#/R-BTA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Bos taurus 41001 R-CEL-5693691 https://reactome.org/PathwayBrowser/#/R-CEL-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Caenorhabditis elegans 41001 R-CFA-5693691 https://reactome.org/PathwayBrowser/#/R-CFA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Canis familiaris 41001 R-DDI-5693691 https://reactome.org/PathwayBrowser/#/R-DDI-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Dictyostelium discoideum 41001 R-DME-5693691 https://reactome.org/PathwayBrowser/#/R-DME-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Drosophila melanogaster 41001 R-DRE-5693691 https://reactome.org/PathwayBrowser/#/R-DRE-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Danio rerio 41001 R-GGA-5693691 https://reactome.org/PathwayBrowser/#/R-GGA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Gallus gallus 41001 R-HSA-5693691 https://reactome.org/PathwayBrowser/#/R-HSA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG TAS Homo sapiens 41001 R-MMU-5693691 https://reactome.org/PathwayBrowser/#/R-MMU-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Mus musculus 41001 R-RNO-5693691 https://reactome.org/PathwayBrowser/#/R-RNO-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Rattus norvegicus 41001 R-SSC-5693691 https://reactome.org/PathwayBrowser/#/R-SSC-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Sus scrofa 41001 R-XTR-5693691 https://reactome.org/PathwayBrowser/#/R-XTR-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Xenopus tropicalis 41218 R-HSA-175976 https://reactome.org/PathwayBrowser/#/R-HSA-175976 TMT transfers CH3 from AdoMet to BME TAS Homo sapiens 41423 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 41423 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 41423 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 41423 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 41423 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 41423 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 41423 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 41423 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 41423 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 41423 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 41423 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 41423 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 41423 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 41423 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 41423 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 41423 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 41423 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 41423 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 41609 R-BTA-1222491 https://reactome.org/PathwayBrowser/#/R-BTA-1222491 Lactoferrin scavenges iron ions IEA Bos taurus 41609 R-CFA-1222491 https://reactome.org/PathwayBrowser/#/R-CFA-1222491 Lactoferrin scavenges iron ions IEA Canis familiaris 41609 R-DME-1222491 https://reactome.org/PathwayBrowser/#/R-DME-1222491 Lactoferrin scavenges iron ions IEA Drosophila melanogaster 41609 R-GGA-1222491 https://reactome.org/PathwayBrowser/#/R-GGA-1222491 Lactoferrin scavenges iron ions IEA Gallus gallus 41609 R-HSA-1222491 https://reactome.org/PathwayBrowser/#/R-HSA-1222491 Lactoferrin scavenges iron ions TAS Homo sapiens 41609 R-HSA-1222641 https://reactome.org/PathwayBrowser/#/R-HSA-1222641 Carboxymycobactin binds LTF:2xFe3+:2xCO3(2-) TAS Homo sapiens 41609 R-HSA-8951549 https://reactome.org/PathwayBrowser/#/R-HSA-8951549 Carbocymycobactin binds Fe3+ from LTF:2xFe3+:2xCO3(2-) TAS Homo sapiens 41609 R-HSA-8951552 https://reactome.org/PathwayBrowser/#/R-HSA-8951552 LTF:2xCO3(2-) dissociates from Carbocymycobactin:Fe3+ TAS Homo sapiens 41609 R-MMU-1222491 https://reactome.org/PathwayBrowser/#/R-MMU-1222491 Lactoferrin scavenges iron ions IEA Mus musculus 41609 R-RNO-1222491 https://reactome.org/PathwayBrowser/#/R-RNO-1222491 Lactoferrin scavenges iron ions IEA Rattus norvegicus 41609 R-SSC-1222491 https://reactome.org/PathwayBrowser/#/R-SSC-1222491 Lactoferrin scavenges iron ions IEA Sus scrofa 41609 R-XTR-1222491 https://reactome.org/PathwayBrowser/#/R-XTR-1222491 Lactoferrin scavenges iron ions IEA Xenopus tropicalis 41633 R-BTA-9024326 https://reactome.org/PathwayBrowser/#/R-BTA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Bos taurus 41633 R-BTA-9024334 https://reactome.org/PathwayBrowser/#/R-BTA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Bos taurus 41633 R-BTA-9029517 https://reactome.org/PathwayBrowser/#/R-BTA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Bos taurus 41633 R-BTA-9029551 https://reactome.org/PathwayBrowser/#/R-BTA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Bos taurus 41633 R-BTA-9029561 https://reactome.org/PathwayBrowser/#/R-BTA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Bos taurus 41633 R-BTA-9029566 https://reactome.org/PathwayBrowser/#/R-BTA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Bos taurus 41633 R-BTA-9029580 https://reactome.org/PathwayBrowser/#/R-BTA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Bos taurus 41633 R-CFA-9024326 https://reactome.org/PathwayBrowser/#/R-CFA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Canis familiaris 41633 R-CFA-9024334 https://reactome.org/PathwayBrowser/#/R-CFA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Canis familiaris 41633 R-CFA-9029517 https://reactome.org/PathwayBrowser/#/R-CFA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Canis familiaris 41633 R-CFA-9029551 https://reactome.org/PathwayBrowser/#/R-CFA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Canis familiaris 41633 R-CFA-9029561 https://reactome.org/PathwayBrowser/#/R-CFA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Canis familiaris 41633 R-CFA-9029566 https://reactome.org/PathwayBrowser/#/R-CFA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Canis familiaris 41633 R-CFA-9029580 https://reactome.org/PathwayBrowser/#/R-CFA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Canis familiaris 41633 R-DME-9024326 https://reactome.org/PathwayBrowser/#/R-DME-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Drosophila melanogaster 41633 R-DME-9024334 https://reactome.org/PathwayBrowser/#/R-DME-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Drosophila melanogaster 41633 R-DME-9029517 https://reactome.org/PathwayBrowser/#/R-DME-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Drosophila melanogaster 41633 R-DME-9029551 https://reactome.org/PathwayBrowser/#/R-DME-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Drosophila melanogaster 41633 R-DME-9029561 https://reactome.org/PathwayBrowser/#/R-DME-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Drosophila melanogaster 41633 R-DME-9029566 https://reactome.org/PathwayBrowser/#/R-DME-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Drosophila melanogaster 41633 R-DME-9029580 https://reactome.org/PathwayBrowser/#/R-DME-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Drosophila melanogaster 41633 R-HSA-9024326 https://reactome.org/PathwayBrowser/#/R-HSA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex TAS Homo sapiens 41633 R-HSA-9024334 https://reactome.org/PathwayBrowser/#/R-HSA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene TAS Homo sapiens 41633 R-HSA-9024361 https://reactome.org/PathwayBrowser/#/R-HSA-9024361 Expression of ABCG1 regulated by NR1H2,3 TAS Homo sapiens 41633 R-HSA-9024386 https://reactome.org/PathwayBrowser/#/R-HSA-9024386 Oxysterol-induced binding of NR1H2,3:RXR to the ABCG1 gene TAS Homo sapiens 41633 R-HSA-9028524 https://reactome.org/PathwayBrowser/#/R-HSA-9028524 NR1H3, NRIP1 bind the PCK1 gene TAS Homo sapiens 41633 R-HSA-9028525 https://reactome.org/PathwayBrowser/#/R-HSA-9028525 NR1H2 or NR1H3, NRIP1 bind the SREBF1 gene TAS Homo sapiens 41633 R-HSA-9028526 https://reactome.org/PathwayBrowser/#/R-HSA-9028526 NR1H2 or NR1H3, NRIP1 bind the SCD gene TAS Homo sapiens 41633 R-HSA-9028533 https://reactome.org/PathwayBrowser/#/R-HSA-9028533 NR1H2,3, NRIP1 bind the FASN gene TAS Homo sapiens 41633 R-HSA-9029517 https://reactome.org/PathwayBrowser/#/R-HSA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex TAS Homo sapiens 41633 R-HSA-9029521 https://reactome.org/PathwayBrowser/#/R-HSA-9029521 NR1H2,3 binds the ABCG5 gene TAS Homo sapiens 41633 R-HSA-9029531 https://reactome.org/PathwayBrowser/#/R-HSA-9029531 Expression of ABCG5 regulated by NR1H2,3 TAS Homo sapiens 41633 R-HSA-9029536 https://reactome.org/PathwayBrowser/#/R-HSA-9029536 Expression of UGT1A3 TAS Homo sapiens 41633 R-HSA-9029551 https://reactome.org/PathwayBrowser/#/R-HSA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex TAS Homo sapiens 41633 R-HSA-9029555 https://reactome.org/PathwayBrowser/#/R-HSA-9029555 NR1H2,3 binds the ABCG8 gene TAS Homo sapiens 41633 R-HSA-9029561 https://reactome.org/PathwayBrowser/#/R-HSA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter TAS Homo sapiens 41633 R-HSA-9029566 https://reactome.org/PathwayBrowser/#/R-HSA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene TAS Homo sapiens 41633 R-HSA-9029580 https://reactome.org/PathwayBrowser/#/R-HSA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex TAS Homo sapiens 41633 R-HSA-9029591 https://reactome.org/PathwayBrowser/#/R-HSA-9029591 Expression of ABCG8 regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9031510 https://reactome.org/PathwayBrowser/#/R-HSA-9031510 Expression of APOC1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9031512 https://reactome.org/PathwayBrowser/#/R-HSA-9031512 Expression of APOE regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9031518 https://reactome.org/PathwayBrowser/#/R-HSA-9031518 NR1H2,3 binds the APOC1 gene TAS Homo sapiens 41633 R-HSA-9031521 https://reactome.org/PathwayBrowser/#/R-HSA-9031521 NR1H2,3 binds the APOC2 gene TAS Homo sapiens 41633 R-HSA-9031522 https://reactome.org/PathwayBrowser/#/R-HSA-9031522 NR1H2,3 binds the APOE gene TAS Homo sapiens 41633 R-HSA-9031527 https://reactome.org/PathwayBrowser/#/R-HSA-9031527 Expression of APOC2 regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9035133 https://reactome.org/PathwayBrowser/#/R-HSA-9035133 NR1H2,3 binds the CETP gene TAS Homo sapiens 41633 R-HSA-9035143 https://reactome.org/PathwayBrowser/#/R-HSA-9035143 NR1H2,3 binds the APOC4 gene TAS Homo sapiens 41633 R-HSA-9035167 https://reactome.org/PathwayBrowser/#/R-HSA-9035167 NR1H2,3 binds the EEPD1 gene TAS Homo sapiens 41633 R-HSA-9035169 https://reactome.org/PathwayBrowser/#/R-HSA-9035169 Expression of CETP regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9035180 https://reactome.org/PathwayBrowser/#/R-HSA-9035180 Expression of EEPD1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9035185 https://reactome.org/PathwayBrowser/#/R-HSA-9035185 NR1H2,3 binds the NR1H3 gene TAS Homo sapiens 41633 R-HSA-9035279 https://reactome.org/PathwayBrowser/#/R-HSA-9035279 Expression of APOC4 regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9035281 https://reactome.org/PathwayBrowser/#/R-HSA-9035281 NR1H3 gene transcription regulated by NR1H2,3 TAS Homo sapiens 41633 R-HSA-9605051 https://reactome.org/PathwayBrowser/#/R-HSA-9605051 Expression of PCK1 regulated by NR1H3 TAS Homo sapiens 41633 R-HSA-9605056 https://reactome.org/PathwayBrowser/#/R-HSA-9605056 Expression of SREBF1 (SREBP1) regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9605057 https://reactome.org/PathwayBrowser/#/R-HSA-9605057 ABCA1 gene transcription regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9605060 https://reactome.org/PathwayBrowser/#/R-HSA-9605060 Expression of SCD regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9605063 https://reactome.org/PathwayBrowser/#/R-HSA-9605063 Expression of FASN regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9607342 https://reactome.org/PathwayBrowser/#/R-HSA-9607342 Expression of FABP6 regulated by NR1H2,3 TAS Homo sapiens 41633 R-HSA-9608039 https://reactome.org/PathwayBrowser/#/R-HSA-9608039 NR1H2,3 binds the PLIN1 gene TAS Homo sapiens 41633 R-HSA-9608048 https://reactome.org/PathwayBrowser/#/R-HSA-9608048 Expression of PLIN1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9618394 https://reactome.org/PathwayBrowser/#/R-HSA-9618394 ARL4C gene transcription regulated by NR1H2,3 TAS Homo sapiens 41633 R-HSA-9618407 https://reactome.org/PathwayBrowser/#/R-HSA-9618407 NR1H2,3 binds the ARL4C gene TAS Homo sapiens 41633 R-HSA-9623365 https://reactome.org/PathwayBrowser/#/R-HSA-9623365 Expression of MYLIP regulated by NR1H2,3 TAS Homo sapiens 41633 R-HSA-9623366 https://reactome.org/PathwayBrowser/#/R-HSA-9623366 NR1H2,3 binds the MYLIP gene TAS Homo sapiens 41633 R-HSA-9624353 https://reactome.org/PathwayBrowser/#/R-HSA-9624353 NR1H2,3 binds the PLTP gene TAS Homo sapiens 41633 R-HSA-9624365 https://reactome.org/PathwayBrowser/#/R-HSA-9624365 Expression of PLTP regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9631296 https://reactome.org/PathwayBrowser/#/R-HSA-9631296 NR1H2,3 binds the FABP6 gene TAS Homo sapiens 41633 R-HSA-9657767 https://reactome.org/PathwayBrowser/#/R-HSA-9657767 Expression of APOD regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9657775 https://reactome.org/PathwayBrowser/#/R-HSA-9657775 Expression of ANGPTL3 regulated by NR1H2 or NR1H3 TAS Homo sapiens 41633 R-HSA-9657786 https://reactome.org/PathwayBrowser/#/R-HSA-9657786 NR1H2,3 binds the APOD gene TAS Homo sapiens 41633 R-HSA-9657836 https://reactome.org/PathwayBrowser/#/R-HSA-9657836 NR1H2,3 binds the ANGPTL3 gene TAS Homo sapiens 41633 R-MMU-9024326 https://reactome.org/PathwayBrowser/#/R-MMU-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Mus musculus 41633 R-MMU-9024334 https://reactome.org/PathwayBrowser/#/R-MMU-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Mus musculus 41633 R-MMU-9029517 https://reactome.org/PathwayBrowser/#/R-MMU-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Mus musculus 41633 R-MMU-9029551 https://reactome.org/PathwayBrowser/#/R-MMU-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Mus musculus 41633 R-MMU-9029561 https://reactome.org/PathwayBrowser/#/R-MMU-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Mus musculus 41633 R-MMU-9029566 https://reactome.org/PathwayBrowser/#/R-MMU-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Mus musculus 41633 R-MMU-9029580 https://reactome.org/PathwayBrowser/#/R-MMU-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Mus musculus 41633 R-RNO-9024326 https://reactome.org/PathwayBrowser/#/R-RNO-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Rattus norvegicus 41633 R-RNO-9024334 https://reactome.org/PathwayBrowser/#/R-RNO-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Rattus norvegicus 41633 R-RNO-9029517 https://reactome.org/PathwayBrowser/#/R-RNO-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Rattus norvegicus 41633 R-RNO-9029551 https://reactome.org/PathwayBrowser/#/R-RNO-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Rattus norvegicus 41633 R-RNO-9029561 https://reactome.org/PathwayBrowser/#/R-RNO-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Rattus norvegicus 41633 R-RNO-9029566 https://reactome.org/PathwayBrowser/#/R-RNO-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Rattus norvegicus 41633 R-RNO-9029580 https://reactome.org/PathwayBrowser/#/R-RNO-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Rattus norvegicus 41633 R-SSC-9024326 https://reactome.org/PathwayBrowser/#/R-SSC-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Sus scrofa 41633 R-SSC-9024334 https://reactome.org/PathwayBrowser/#/R-SSC-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Sus scrofa 41633 R-SSC-9029517 https://reactome.org/PathwayBrowser/#/R-SSC-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Sus scrofa 41633 R-SSC-9029551 https://reactome.org/PathwayBrowser/#/R-SSC-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Sus scrofa 41633 R-SSC-9029561 https://reactome.org/PathwayBrowser/#/R-SSC-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Sus scrofa 41633 R-SSC-9029566 https://reactome.org/PathwayBrowser/#/R-SSC-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Sus scrofa 41633 R-SSC-9029580 https://reactome.org/PathwayBrowser/#/R-SSC-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Sus scrofa 41633 R-XTR-9024326 https://reactome.org/PathwayBrowser/#/R-XTR-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Xenopus tropicalis 41633 R-XTR-9024334 https://reactome.org/PathwayBrowser/#/R-XTR-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Xenopus tropicalis 41633 R-XTR-9029517 https://reactome.org/PathwayBrowser/#/R-XTR-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Xenopus tropicalis 41633 R-XTR-9029566 https://reactome.org/PathwayBrowser/#/R-XTR-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Xenopus tropicalis 4170 R-BTA-1855178 https://reactome.org/PathwayBrowser/#/R-BTA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Bos taurus 4170 R-CEL-1855178 https://reactome.org/PathwayBrowser/#/R-CEL-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Caenorhabditis elegans 4170 R-DDI-1855178 https://reactome.org/PathwayBrowser/#/R-DDI-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Dictyostelium discoideum 4170 R-DME-1855178 https://reactome.org/PathwayBrowser/#/R-DME-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Drosophila melanogaster 4170 R-GGA-1855178 https://reactome.org/PathwayBrowser/#/R-GGA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Gallus gallus 4170 R-HSA-1855178 https://reactome.org/PathwayBrowser/#/R-HSA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol TAS Homo sapiens 4170 R-MMU-1855178 https://reactome.org/PathwayBrowser/#/R-MMU-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Mus musculus 4170 R-PFA-1855178 https://reactome.org/PathwayBrowser/#/R-PFA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Plasmodium falciparum 4170 R-RNO-1855178 https://reactome.org/PathwayBrowser/#/R-RNO-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Rattus norvegicus 4170 R-SCE-1855178 https://reactome.org/PathwayBrowser/#/R-SCE-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Saccharomyces cerevisiae 4170 R-SSC-1855178 https://reactome.org/PathwayBrowser/#/R-SSC-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Sus scrofa 4170 R-XTR-1855178 https://reactome.org/PathwayBrowser/#/R-XTR-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Xenopus tropicalis 41774 R-BTA-174916 https://reactome.org/PathwayBrowser/#/R-BTA-174916 Formation of N-glucuronides IEA Bos taurus 41774 R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 41774 R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 41774 R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 41774 R-DDI-174916 https://reactome.org/PathwayBrowser/#/R-DDI-174916 Formation of N-glucuronides IEA Dictyostelium discoideum 41774 R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 41774 R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 41774 R-GGA-174916 https://reactome.org/PathwayBrowser/#/R-GGA-174916 Formation of N-glucuronides IEA Gallus gallus 41774 R-HSA-174916 https://reactome.org/PathwayBrowser/#/R-HSA-174916 Formation of N-glucuronides TAS Homo sapiens 41774 R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 41774 R-MMU-174916 https://reactome.org/PathwayBrowser/#/R-MMU-174916 Formation of N-glucuronides IEA Mus musculus 41774 R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 41774 R-RNO-174916 https://reactome.org/PathwayBrowser/#/R-RNO-174916 Formation of N-glucuronides IEA Rattus norvegicus 41774 R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 41774 R-SSC-174916 https://reactome.org/PathwayBrowser/#/R-SSC-174916 Formation of N-glucuronides IEA Sus scrofa 41774 R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 41774 R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 4178 R-BTA-1678854 https://reactome.org/PathwayBrowser/#/R-BTA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Bos taurus 4178 R-BTA-2162226 https://reactome.org/PathwayBrowser/#/R-BTA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Bos taurus 4178 R-BTA-2162227 https://reactome.org/PathwayBrowser/#/R-BTA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Bos taurus 4178 R-CEL-1678854 https://reactome.org/PathwayBrowser/#/R-CEL-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Caenorhabditis elegans 4178 R-CEL-2162226 https://reactome.org/PathwayBrowser/#/R-CEL-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Caenorhabditis elegans 4178 R-CEL-2162227 https://reactome.org/PathwayBrowser/#/R-CEL-2162227 GUSB tetramer hydrolyses (HA)2 IEA Caenorhabditis elegans 4178 R-CFA-1678854 https://reactome.org/PathwayBrowser/#/R-CFA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Canis familiaris 4178 R-CFA-2162226 https://reactome.org/PathwayBrowser/#/R-CFA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Canis familiaris 4178 R-CFA-2162227 https://reactome.org/PathwayBrowser/#/R-CFA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Canis familiaris 4178 R-DME-1678854 https://reactome.org/PathwayBrowser/#/R-DME-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Drosophila melanogaster 4178 R-DME-2162226 https://reactome.org/PathwayBrowser/#/R-DME-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Drosophila melanogaster 4178 R-DME-2162227 https://reactome.org/PathwayBrowser/#/R-DME-2162227 GUSB tetramer hydrolyses (HA)2 IEA Drosophila melanogaster 4178 R-GGA-1678854 https://reactome.org/PathwayBrowser/#/R-GGA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Gallus gallus 4178 R-GGA-2162226 https://reactome.org/PathwayBrowser/#/R-GGA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Gallus gallus 4178 R-GGA-2162227 https://reactome.org/PathwayBrowser/#/R-GGA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Gallus gallus 4178 R-HSA-1678854 https://reactome.org/PathwayBrowser/#/R-HSA-1678854 GUSB tetramer hydrolyses CS/HS precursor TAS Homo sapiens 4178 R-HSA-2162226 https://reactome.org/PathwayBrowser/#/R-HSA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc TAS Homo sapiens 4178 R-HSA-2162227 https://reactome.org/PathwayBrowser/#/R-HSA-2162227 GUSB tetramer hydrolyses (HA)2 TAS Homo sapiens 4178 R-HSA-2162229 https://reactome.org/PathwayBrowser/#/R-HSA-2162229 The single sugars GlcA and GlcNAc translocate from the lysosome to the cytosol TAS Homo sapiens 4178 R-MMU-1678854 https://reactome.org/PathwayBrowser/#/R-MMU-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Mus musculus 4178 R-MMU-2162226 https://reactome.org/PathwayBrowser/#/R-MMU-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Mus musculus 4178 R-MMU-2162227 https://reactome.org/PathwayBrowser/#/R-MMU-2162227 GUSB tetramer hydrolyses (HA)2 IEA Mus musculus 4178 R-RNO-1678854 https://reactome.org/PathwayBrowser/#/R-RNO-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Rattus norvegicus 4178 R-RNO-2162226 https://reactome.org/PathwayBrowser/#/R-RNO-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Rattus norvegicus 4178 R-RNO-2162227 https://reactome.org/PathwayBrowser/#/R-RNO-2162227 GUSB tetramer hydrolyses (HA)2 IEA Rattus norvegicus 4178 R-SSC-1678854 https://reactome.org/PathwayBrowser/#/R-SSC-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Sus scrofa 4178 R-SSC-2162226 https://reactome.org/PathwayBrowser/#/R-SSC-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Sus scrofa 4178 R-SSC-2162227 https://reactome.org/PathwayBrowser/#/R-SSC-2162227 GUSB tetramer hydrolyses (HA)2 IEA Sus scrofa 4178 R-XTR-1678854 https://reactome.org/PathwayBrowser/#/R-XTR-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Xenopus tropicalis 4178 R-XTR-2162226 https://reactome.org/PathwayBrowser/#/R-XTR-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Xenopus tropicalis 4178 R-XTR-2162227 https://reactome.org/PathwayBrowser/#/R-XTR-2162227 GUSB tetramer hydrolyses (HA)2 IEA Xenopus tropicalis 41879 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 41879 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 41879 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 41879 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 41879 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 41879 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 41879 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 41879 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 41879 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 41879 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 41879 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 41879 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 41879 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 41879 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 41879 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 41879 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 41879 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 41879 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 41879 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 41879 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 41879 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 41879 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 41879 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 41879 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 41879 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 41879 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 41879 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 41879 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 41879 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 41879 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 41879 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 41879 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 41879 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 41879 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 41879 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 41879 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 41879 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 41879 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 41879 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 41879 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 41879 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 41879 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 4208 R-BTA-2203480 https://reactome.org/PathwayBrowser/#/R-BTA-2203480 COLEC11 binds ligands IEA Bos taurus 4208 R-BTA-429567 https://reactome.org/PathwayBrowser/#/R-BTA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Bos taurus 4208 R-BTA-6799545 https://reactome.org/PathwayBrowser/#/R-BTA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Bos taurus 4208 R-BTA-6799581 https://reactome.org/PathwayBrowser/#/R-BTA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Bos taurus 4208 R-BTA-8853686 https://reactome.org/PathwayBrowser/#/R-BTA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Bos taurus 4208 R-BTA-8853710 https://reactome.org/PathwayBrowser/#/R-BTA-8853710 MANBA hydrolyses GlcNAc:Man IEA Bos taurus 4208 R-BTA-8876283 https://reactome.org/PathwayBrowser/#/R-BTA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Bos taurus 4208 R-BTA-964737 https://reactome.org/PathwayBrowser/#/R-BTA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 4208 R-BTA-964825 https://reactome.org/PathwayBrowser/#/R-BTA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 4208 R-BTA-964830 https://reactome.org/PathwayBrowser/#/R-BTA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 4208 R-BTA-975814 https://reactome.org/PathwayBrowser/#/R-BTA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Bos taurus 4208 R-CEL-6799581 https://reactome.org/PathwayBrowser/#/R-CEL-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Caenorhabditis elegans 4208 R-CEL-8853686 https://reactome.org/PathwayBrowser/#/R-CEL-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Caenorhabditis elegans 4208 R-CEL-8853710 https://reactome.org/PathwayBrowser/#/R-CEL-8853710 MANBA hydrolyses GlcNAc:Man IEA Caenorhabditis elegans 4208 R-CEL-964737 https://reactome.org/PathwayBrowser/#/R-CEL-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 4208 R-CEL-964825 https://reactome.org/PathwayBrowser/#/R-CEL-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 4208 R-CEL-964830 https://reactome.org/PathwayBrowser/#/R-CEL-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 4208 R-CEL-975814 https://reactome.org/PathwayBrowser/#/R-CEL-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Caenorhabditis elegans 4208 R-CFA-429567 https://reactome.org/PathwayBrowser/#/R-CFA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Canis familiaris 4208 R-CFA-6799545 https://reactome.org/PathwayBrowser/#/R-CFA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Canis familiaris 4208 R-CFA-8853686 https://reactome.org/PathwayBrowser/#/R-CFA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Canis familiaris 4208 R-CFA-8853710 https://reactome.org/PathwayBrowser/#/R-CFA-8853710 MANBA hydrolyses GlcNAc:Man IEA Canis familiaris 4208 R-CFA-8876283 https://reactome.org/PathwayBrowser/#/R-CFA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Canis familiaris 4208 R-CFA-964737 https://reactome.org/PathwayBrowser/#/R-CFA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 4208 R-CFA-964825 https://reactome.org/PathwayBrowser/#/R-CFA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 4208 R-CFA-964830 https://reactome.org/PathwayBrowser/#/R-CFA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 4208 R-CFA-975814 https://reactome.org/PathwayBrowser/#/R-CFA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Canis familiaris 4208 R-DDI-6799545 https://reactome.org/PathwayBrowser/#/R-DDI-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Dictyostelium discoideum 4208 R-DDI-6799581 https://reactome.org/PathwayBrowser/#/R-DDI-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Dictyostelium discoideum 4208 R-DDI-8853686 https://reactome.org/PathwayBrowser/#/R-DDI-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Dictyostelium discoideum 4208 R-DDI-8853710 https://reactome.org/PathwayBrowser/#/R-DDI-8853710 MANBA hydrolyses GlcNAc:Man IEA Dictyostelium discoideum 4208 R-DDI-964737 https://reactome.org/PathwayBrowser/#/R-DDI-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 4208 R-DDI-964825 https://reactome.org/PathwayBrowser/#/R-DDI-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 4208 R-DDI-964830 https://reactome.org/PathwayBrowser/#/R-DDI-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 4208 R-DME-6799581 https://reactome.org/PathwayBrowser/#/R-DME-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Drosophila melanogaster 4208 R-DME-8853686 https://reactome.org/PathwayBrowser/#/R-DME-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Drosophila melanogaster 4208 R-DME-8853710 https://reactome.org/PathwayBrowser/#/R-DME-8853710 MANBA hydrolyses GlcNAc:Man IEA Drosophila melanogaster 4208 R-DME-964737 https://reactome.org/PathwayBrowser/#/R-DME-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 4208 R-DME-964825 https://reactome.org/PathwayBrowser/#/R-DME-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 4208 R-DME-964830 https://reactome.org/PathwayBrowser/#/R-DME-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 4208 R-DME-975814 https://reactome.org/PathwayBrowser/#/R-DME-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Drosophila melanogaster 4208 R-DRE-429567 https://reactome.org/PathwayBrowser/#/R-DRE-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Danio rerio 4208 R-DRE-8853710 https://reactome.org/PathwayBrowser/#/R-DRE-8853710 MANBA hydrolyses GlcNAc:Man IEA Danio rerio 4208 R-DRE-964737 https://reactome.org/PathwayBrowser/#/R-DRE-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 4208 R-DRE-964825 https://reactome.org/PathwayBrowser/#/R-DRE-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 4208 R-DRE-964830 https://reactome.org/PathwayBrowser/#/R-DRE-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 4208 R-GGA-2203480 https://reactome.org/PathwayBrowser/#/R-GGA-2203480 COLEC11 binds ligands IEA Gallus gallus 4208 R-GGA-429567 https://reactome.org/PathwayBrowser/#/R-GGA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Gallus gallus 4208 R-GGA-6799545 https://reactome.org/PathwayBrowser/#/R-GGA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Gallus gallus 4208 R-GGA-6799581 https://reactome.org/PathwayBrowser/#/R-GGA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Gallus gallus 4208 R-GGA-8853710 https://reactome.org/PathwayBrowser/#/R-GGA-8853710 MANBA hydrolyses GlcNAc:Man IEA Gallus gallus 4208 R-GGA-8876283 https://reactome.org/PathwayBrowser/#/R-GGA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Gallus gallus 4208 R-GGA-964737 https://reactome.org/PathwayBrowser/#/R-GGA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 4208 R-GGA-964825 https://reactome.org/PathwayBrowser/#/R-GGA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 4208 R-GGA-964830 https://reactome.org/PathwayBrowser/#/R-GGA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 4208 R-GGA-975814 https://reactome.org/PathwayBrowser/#/R-GGA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Gallus gallus 4208 R-HSA-2203480 https://reactome.org/PathwayBrowser/#/R-HSA-2203480 COLEC11 binds ligands TAS Homo sapiens 4208 R-HSA-429567 https://reactome.org/PathwayBrowser/#/R-HSA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 TAS Homo sapiens 4208 R-HSA-6782685 https://reactome.org/PathwayBrowser/#/R-HSA-6782685 EDEM1,3 hydrolyse (GlcNAc)2 (Man)8b to (GlcNAc)2 (Man)5 TAS Homo sapiens 4208 R-HSA-6799545 https://reactome.org/PathwayBrowser/#/R-HSA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 TAS Homo sapiens 4208 R-HSA-6799581 https://reactome.org/PathwayBrowser/#/R-HSA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man TAS Homo sapiens 4208 R-HSA-8853686 https://reactome.org/PathwayBrowser/#/R-HSA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 TAS Homo sapiens 4208 R-HSA-8853710 https://reactome.org/PathwayBrowser/#/R-HSA-8853710 MANBA hydrolyses GlcNAc:Man TAS Homo sapiens 4208 R-HSA-8876283 https://reactome.org/PathwayBrowser/#/R-HSA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol TAS Homo sapiens 4208 R-HSA-901024 https://reactome.org/PathwayBrowser/#/R-HSA-901024 MAN1B1 hydrolyses 1,2-linked mannose (a branch) TAS Homo sapiens 4208 R-HSA-901036 https://reactome.org/PathwayBrowser/#/R-HSA-901036 MAN1B1 hydrolyses a second 1,2-linked mannose (a branch) TAS Homo sapiens 4208 R-HSA-901039 https://reactome.org/PathwayBrowser/#/R-HSA-901039 MAN1B1 hydrolyses 1,2-linked mannose (c branch) TAS Homo sapiens 4208 R-HSA-901074 https://reactome.org/PathwayBrowser/#/R-HSA-901074 MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch) TAS Homo sapiens 4208 R-HSA-964737 https://reactome.org/PathwayBrowser/#/R-HSA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 4208 R-HSA-964825 https://reactome.org/PathwayBrowser/#/R-HSA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 4208 R-HSA-964830 https://reactome.org/PathwayBrowser/#/R-HSA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 4208 R-HSA-975814 https://reactome.org/PathwayBrowser/#/R-HSA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 TAS Homo sapiens 4208 R-MMU-2203480 https://reactome.org/PathwayBrowser/#/R-MMU-2203480 COLEC11 binds ligands IEA Mus musculus 4208 R-MMU-429567 https://reactome.org/PathwayBrowser/#/R-MMU-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Mus musculus 4208 R-MMU-6799545 https://reactome.org/PathwayBrowser/#/R-MMU-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Mus musculus 4208 R-MMU-6799581 https://reactome.org/PathwayBrowser/#/R-MMU-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Mus musculus 4208 R-MMU-8853686 https://reactome.org/PathwayBrowser/#/R-MMU-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Mus musculus 4208 R-MMU-8853710 https://reactome.org/PathwayBrowser/#/R-MMU-8853710 MANBA hydrolyses GlcNAc:Man IEA Mus musculus 4208 R-MMU-8876283 https://reactome.org/PathwayBrowser/#/R-MMU-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Mus musculus 4208 R-MMU-964737 https://reactome.org/PathwayBrowser/#/R-MMU-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 4208 R-MMU-964825 https://reactome.org/PathwayBrowser/#/R-MMU-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 4208 R-MMU-964830 https://reactome.org/PathwayBrowser/#/R-MMU-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 4208 R-MMU-975814 https://reactome.org/PathwayBrowser/#/R-MMU-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Mus musculus 4208 R-RNO-429567 https://reactome.org/PathwayBrowser/#/R-RNO-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Rattus norvegicus 4208 R-RNO-6799545 https://reactome.org/PathwayBrowser/#/R-RNO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Rattus norvegicus 4208 R-RNO-6799581 https://reactome.org/PathwayBrowser/#/R-RNO-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Rattus norvegicus 4208 R-RNO-8853686 https://reactome.org/PathwayBrowser/#/R-RNO-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Rattus norvegicus 4208 R-RNO-8853710 https://reactome.org/PathwayBrowser/#/R-RNO-8853710 MANBA hydrolyses GlcNAc:Man IEA Rattus norvegicus 4208 R-RNO-8876283 https://reactome.org/PathwayBrowser/#/R-RNO-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Rattus norvegicus 4208 R-RNO-964737 https://reactome.org/PathwayBrowser/#/R-RNO-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 4208 R-RNO-964825 https://reactome.org/PathwayBrowser/#/R-RNO-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 4208 R-RNO-964830 https://reactome.org/PathwayBrowser/#/R-RNO-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 4208 R-RNO-975814 https://reactome.org/PathwayBrowser/#/R-RNO-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Rattus norvegicus 4208 R-SCE-6799545 https://reactome.org/PathwayBrowser/#/R-SCE-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Saccharomyces cerevisiae 4208 R-SPO-6799545 https://reactome.org/PathwayBrowser/#/R-SPO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Schizosaccharomyces pombe 4208 R-SSC-2203480 https://reactome.org/PathwayBrowser/#/R-SSC-2203480 COLEC11 binds ligands IEA Sus scrofa 4208 R-SSC-429567 https://reactome.org/PathwayBrowser/#/R-SSC-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Sus scrofa 4208 R-SSC-6799545 https://reactome.org/PathwayBrowser/#/R-SSC-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Sus scrofa 4208 R-SSC-6799581 https://reactome.org/PathwayBrowser/#/R-SSC-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Sus scrofa 4208 R-SSC-8853686 https://reactome.org/PathwayBrowser/#/R-SSC-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Sus scrofa 4208 R-SSC-8853710 https://reactome.org/PathwayBrowser/#/R-SSC-8853710 MANBA hydrolyses GlcNAc:Man IEA Sus scrofa 4208 R-SSC-8876283 https://reactome.org/PathwayBrowser/#/R-SSC-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Sus scrofa 4208 R-SSC-964737 https://reactome.org/PathwayBrowser/#/R-SSC-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 4208 R-SSC-964825 https://reactome.org/PathwayBrowser/#/R-SSC-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 4208 R-SSC-964830 https://reactome.org/PathwayBrowser/#/R-SSC-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 4208 R-SSC-975814 https://reactome.org/PathwayBrowser/#/R-SSC-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Sus scrofa 4208 R-XTR-6799545 https://reactome.org/PathwayBrowser/#/R-XTR-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Xenopus tropicalis 4208 R-XTR-6799581 https://reactome.org/PathwayBrowser/#/R-XTR-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Xenopus tropicalis 4208 R-XTR-8853686 https://reactome.org/PathwayBrowser/#/R-XTR-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Xenopus tropicalis 4208 R-XTR-8853710 https://reactome.org/PathwayBrowser/#/R-XTR-8853710 MANBA hydrolyses GlcNAc:Man IEA Xenopus tropicalis 4208 R-XTR-8876283 https://reactome.org/PathwayBrowser/#/R-XTR-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Xenopus tropicalis 4208 R-XTR-964737 https://reactome.org/PathwayBrowser/#/R-XTR-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 4208 R-XTR-964825 https://reactome.org/PathwayBrowser/#/R-XTR-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 4208 R-XTR-964830 https://reactome.org/PathwayBrowser/#/R-XTR-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 4208 R-XTR-975814 https://reactome.org/PathwayBrowser/#/R-XTR-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Xenopus tropicalis 421707 R-BTA-2161500 https://reactome.org/PathwayBrowser/#/R-BTA-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Bos taurus 421707 R-BTA-2162078 https://reactome.org/PathwayBrowser/#/R-BTA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Bos taurus 421707 R-CEL-2161500 https://reactome.org/PathwayBrowser/#/R-CEL-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Caenorhabditis elegans 421707 R-CEL-2162078 https://reactome.org/PathwayBrowser/#/R-CEL-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Caenorhabditis elegans 421707 R-CFA-2161500 https://reactome.org/PathwayBrowser/#/R-CFA-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Canis familiaris 421707 R-CFA-2162078 https://reactome.org/PathwayBrowser/#/R-CFA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Canis familiaris 421707 R-DDI-2162078 https://reactome.org/PathwayBrowser/#/R-DDI-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Dictyostelium discoideum 421707 R-DME-2161500 https://reactome.org/PathwayBrowser/#/R-DME-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Drosophila melanogaster 421707 R-DME-2162078 https://reactome.org/PathwayBrowser/#/R-DME-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Drosophila melanogaster 421707 R-DRE-2161500 https://reactome.org/PathwayBrowser/#/R-DRE-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Danio rerio 421707 R-DRE-2162078 https://reactome.org/PathwayBrowser/#/R-DRE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Danio rerio 421707 R-GGA-2161500 https://reactome.org/PathwayBrowser/#/R-GGA-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Gallus gallus 421707 R-GGA-2162078 https://reactome.org/PathwayBrowser/#/R-GGA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Gallus gallus 421707 R-HSA-2161193 https://reactome.org/PathwayBrowser/#/R-HSA-2161193 abacavir + AMP => abacavir monophosphate + adenosine TAS Homo sapiens 421707 R-HSA-2161500 https://reactome.org/PathwayBrowser/#/R-HSA-2161500 abacavir [extracellular] => abacavir [cytosol] TAS Homo sapiens 421707 R-HSA-2161506 https://reactome.org/PathwayBrowser/#/R-HSA-2161506 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 421707 R-HSA-2161538 https://reactome.org/PathwayBrowser/#/R-HSA-2161538 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 421707 R-HSA-2162078 https://reactome.org/PathwayBrowser/#/R-HSA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ TAS Homo sapiens 421707 R-HSA-2162099 https://reactome.org/PathwayBrowser/#/R-HSA-2162099 abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP TAS Homo sapiens 421707 R-MMU-2161500 https://reactome.org/PathwayBrowser/#/R-MMU-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Mus musculus 421707 R-MMU-2161526 https://reactome.org/PathwayBrowser/#/R-MMU-2161526 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 421707 R-MMU-2161533 https://reactome.org/PathwayBrowser/#/R-MMU-2161533 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 421707 R-MMU-2162078 https://reactome.org/PathwayBrowser/#/R-MMU-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Mus musculus 421707 R-RNO-2161500 https://reactome.org/PathwayBrowser/#/R-RNO-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Rattus norvegicus 421707 R-RNO-2162078 https://reactome.org/PathwayBrowser/#/R-RNO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Rattus norvegicus 421707 R-SCE-2162078 https://reactome.org/PathwayBrowser/#/R-SCE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Saccharomyces cerevisiae 421707 R-SPO-2162078 https://reactome.org/PathwayBrowser/#/R-SPO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Schizosaccharomyces pombe 421707 R-SSC-2161500 https://reactome.org/PathwayBrowser/#/R-SSC-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Sus scrofa 421707 R-SSC-2162078 https://reactome.org/PathwayBrowser/#/R-SSC-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Sus scrofa 421707 R-XTR-2161500 https://reactome.org/PathwayBrowser/#/R-XTR-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Xenopus tropicalis 421707 R-XTR-2162078 https://reactome.org/PathwayBrowser/#/R-XTR-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Xenopus tropicalis 422 R-BTA-3296326 https://reactome.org/PathwayBrowser/#/R-BTA-3296326 HCAR1 binds LACT IEA Bos taurus 422 R-BTA-373867 https://reactome.org/PathwayBrowser/#/R-BTA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Bos taurus 422 R-BTA-373875 https://reactome.org/PathwayBrowser/#/R-BTA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Bos taurus 422 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 422 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Bos taurus 422 R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 422 R-BTA-561253 https://reactome.org/PathwayBrowser/#/R-BTA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Bos taurus 422 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 422 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 422 R-BTA-8876312 https://reactome.org/PathwayBrowser/#/R-BTA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Bos taurus 422 R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 422 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 422 R-CEL-373867 https://reactome.org/PathwayBrowser/#/R-CEL-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 422 R-CEL-373875 https://reactome.org/PathwayBrowser/#/R-CEL-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Caenorhabditis elegans 422 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Caenorhabditis elegans 422 R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 422 R-CEL-561253 https://reactome.org/PathwayBrowser/#/R-CEL-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Caenorhabditis elegans 422 R-CEL-6807826 https://reactome.org/PathwayBrowser/#/R-CEL-6807826 LDHAL6B reduces PYR to LACT IEA Caenorhabditis elegans 422 R-CEL-8876312 https://reactome.org/PathwayBrowser/#/R-CEL-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Caenorhabditis elegans 422 R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 422 R-CFA-3296326 https://reactome.org/PathwayBrowser/#/R-CFA-3296326 HCAR1 binds LACT IEA Canis familiaris 422 R-CFA-373867 https://reactome.org/PathwayBrowser/#/R-CFA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Canis familiaris 422 R-CFA-373875 https://reactome.org/PathwayBrowser/#/R-CFA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Canis familiaris 422 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 422 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Canis familiaris 422 R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 422 R-CFA-561253 https://reactome.org/PathwayBrowser/#/R-CFA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Canis familiaris 422 R-CFA-6807826 https://reactome.org/PathwayBrowser/#/R-CFA-6807826 LDHAL6B reduces PYR to LACT IEA Canis familiaris 422 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 422 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 422 R-CFA-8876312 https://reactome.org/PathwayBrowser/#/R-CFA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Canis familiaris 422 R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 422 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 422 R-DME-373867 https://reactome.org/PathwayBrowser/#/R-DME-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Drosophila melanogaster 422 R-DME-373875 https://reactome.org/PathwayBrowser/#/R-DME-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Drosophila melanogaster 422 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Drosophila melanogaster 422 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 422 R-DME-561253 https://reactome.org/PathwayBrowser/#/R-DME-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Drosophila melanogaster 422 R-DME-6807826 https://reactome.org/PathwayBrowser/#/R-DME-6807826 LDHAL6B reduces PYR to LACT IEA Drosophila melanogaster 422 R-DME-8876312 https://reactome.org/PathwayBrowser/#/R-DME-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Drosophila melanogaster 422 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 422 R-DRE-3296326 https://reactome.org/PathwayBrowser/#/R-DRE-3296326 HCAR1 binds LACT IEA Danio rerio 422 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 422 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Danio rerio 422 R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 422 R-DRE-6807826 https://reactome.org/PathwayBrowser/#/R-DRE-6807826 LDHAL6B reduces PYR to LACT IEA Danio rerio 422 R-DRE-8876312 https://reactome.org/PathwayBrowser/#/R-DRE-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Danio rerio 422 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 422 R-GGA-373867 https://reactome.org/PathwayBrowser/#/R-GGA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Gallus gallus 422 R-GGA-373875 https://reactome.org/PathwayBrowser/#/R-GGA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Gallus gallus 422 R-GGA-373887 https://reactome.org/PathwayBrowser/#/R-GGA-373887 lactate + H+ [extracellular] <=> lactate + H+ [cytosol] IEA Gallus gallus 422 R-GGA-373889 https://reactome.org/PathwayBrowser/#/R-GGA-373889 lactate + H+ [cytosol] <=> lactate + H+ [extracellular] IEA Gallus gallus 422 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Gallus gallus 422 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 422 R-GGA-6807826 https://reactome.org/PathwayBrowser/#/R-GGA-6807826 LDHAL6B reduces PYR to LACT IEA Gallus gallus 422 R-GGA-8876312 https://reactome.org/PathwayBrowser/#/R-GGA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Gallus gallus 422 R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 422 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 422 R-HSA-3296326 https://reactome.org/PathwayBrowser/#/R-HSA-3296326 HCAR1 binds LACT TAS Homo sapiens 422 R-HSA-373867 https://reactome.org/PathwayBrowser/#/R-HSA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol TAS Homo sapiens 422 R-HSA-373875 https://reactome.org/PathwayBrowser/#/R-HSA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region TAS Homo sapiens 422 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 422 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol TAS Homo sapiens 422 R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 422 R-HSA-561253 https://reactome.org/PathwayBrowser/#/R-HSA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT TAS Homo sapiens 422 R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 422 R-HSA-6807826 https://reactome.org/PathwayBrowser/#/R-HSA-6807826 LDHAL6B reduces PYR to LACT TAS Homo sapiens 422 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 422 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 422 R-HSA-8876312 https://reactome.org/PathwayBrowser/#/R-HSA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol TAS Homo sapiens 422 R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 422 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 422 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 422 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 422 R-MMU-3296326 https://reactome.org/PathwayBrowser/#/R-MMU-3296326 HCAR1 binds LACT IEA Mus musculus 422 R-MMU-373867 https://reactome.org/PathwayBrowser/#/R-MMU-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Mus musculus 422 R-MMU-373875 https://reactome.org/PathwayBrowser/#/R-MMU-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Mus musculus 422 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 422 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Mus musculus 422 R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 422 R-MMU-561253 https://reactome.org/PathwayBrowser/#/R-MMU-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Mus musculus 422 R-MMU-6807826 https://reactome.org/PathwayBrowser/#/R-MMU-6807826 LDHAL6B reduces PYR to LACT IEA Mus musculus 422 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 422 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 422 R-MMU-8876312 https://reactome.org/PathwayBrowser/#/R-MMU-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Mus musculus 422 R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 422 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 422 R-RNO-3296326 https://reactome.org/PathwayBrowser/#/R-RNO-3296326 HCAR1 binds LACT IEA Rattus norvegicus 422 R-RNO-373867 https://reactome.org/PathwayBrowser/#/R-RNO-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Rattus norvegicus 422 R-RNO-373875 https://reactome.org/PathwayBrowser/#/R-RNO-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Rattus norvegicus 422 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 422 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Rattus norvegicus 422 R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 422 R-RNO-561253 https://reactome.org/PathwayBrowser/#/R-RNO-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Rattus norvegicus 422 R-RNO-6807826 https://reactome.org/PathwayBrowser/#/R-RNO-6807826 LDHAL6B reduces PYR to LACT IEA Rattus norvegicus 422 R-RNO-8876312 https://reactome.org/PathwayBrowser/#/R-RNO-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Rattus norvegicus 422 R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 422 R-SSC-3296326 https://reactome.org/PathwayBrowser/#/R-SSC-3296326 HCAR1 binds LACT IEA Sus scrofa 422 R-SSC-373867 https://reactome.org/PathwayBrowser/#/R-SSC-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Sus scrofa 422 R-SSC-373875 https://reactome.org/PathwayBrowser/#/R-SSC-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Sus scrofa 422 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 422 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Sus scrofa 422 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 422 R-SSC-561253 https://reactome.org/PathwayBrowser/#/R-SSC-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Sus scrofa 422 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 422 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 422 R-SSC-8876312 https://reactome.org/PathwayBrowser/#/R-SSC-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Sus scrofa 422 R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 422 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 422 R-XTR-373867 https://reactome.org/PathwayBrowser/#/R-XTR-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Xenopus tropicalis 422 R-XTR-373875 https://reactome.org/PathwayBrowser/#/R-XTR-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Xenopus tropicalis 422 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 transports monocarboxylates from extracellular region to cytosol IEA Xenopus tropicalis 422 R-XTR-6807826 https://reactome.org/PathwayBrowser/#/R-XTR-6807826 LDHAL6B reduces PYR to LACT IEA Xenopus tropicalis 422 R-XTR-8876312 https://reactome.org/PathwayBrowser/#/R-XTR-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Xenopus tropicalis 422 R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 42504 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 42504 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 42504 R-BTA-400434 https://reactome.org/PathwayBrowser/#/R-BTA-400434 FFAR1 binds fatty acids IEA Bos taurus 42504 R-BTA-400509 https://reactome.org/PathwayBrowser/#/R-BTA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Bos taurus 42504 R-BTA-416530 https://reactome.org/PathwayBrowser/#/R-BTA-416530 FFAR1:FFAR1 ligands activate Gq IEA Bos taurus 42504 R-BTA-444202 https://reactome.org/PathwayBrowser/#/R-BTA-444202 Receptor FFAR1 binds free fatty acids IEA Bos taurus 42504 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 42504 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 42504 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 42504 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 42504 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 42504 R-CFA-400434 https://reactome.org/PathwayBrowser/#/R-CFA-400434 FFAR1 binds fatty acids IEA Canis familiaris 42504 R-CFA-400509 https://reactome.org/PathwayBrowser/#/R-CFA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Canis familiaris 42504 R-CFA-416530 https://reactome.org/PathwayBrowser/#/R-CFA-416530 FFAR1:FFAR1 ligands activate Gq IEA Canis familiaris 42504 R-CFA-444202 https://reactome.org/PathwayBrowser/#/R-CFA-444202 Receptor FFAR1 binds free fatty acids IEA Canis familiaris 42504 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 42504 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 42504 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 42504 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 42504 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 42504 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 42504 R-HSA-400434 https://reactome.org/PathwayBrowser/#/R-HSA-400434 FFAR1 binds fatty acids TAS Homo sapiens 42504 R-HSA-400509 https://reactome.org/PathwayBrowser/#/R-HSA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells TAS Homo sapiens 42504 R-HSA-416530 https://reactome.org/PathwayBrowser/#/R-HSA-416530 FFAR1:FFAR1 ligands activate Gq TAS Homo sapiens 42504 R-HSA-444202 https://reactome.org/PathwayBrowser/#/R-HSA-444202 Receptor FFAR1 binds free fatty acids TAS Homo sapiens 42504 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 42504 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 42504 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 42504 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 42504 R-MMU-400434 https://reactome.org/PathwayBrowser/#/R-MMU-400434 FFAR1 binds fatty acids IEA Mus musculus 42504 R-MMU-400509 https://reactome.org/PathwayBrowser/#/R-MMU-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Mus musculus 42504 R-MMU-416530 https://reactome.org/PathwayBrowser/#/R-MMU-416530 FFAR1:FFAR1 ligands activate Gq IEA Mus musculus 42504 R-MMU-444202 https://reactome.org/PathwayBrowser/#/R-MMU-444202 Receptor FFAR1 binds free fatty acids IEA Mus musculus 42504 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 42504 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 42504 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 42504 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 42504 R-RNO-400434 https://reactome.org/PathwayBrowser/#/R-RNO-400434 FFAR1 binds fatty acids IEA Rattus norvegicus 42504 R-RNO-400509 https://reactome.org/PathwayBrowser/#/R-RNO-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Rattus norvegicus 42504 R-RNO-416530 https://reactome.org/PathwayBrowser/#/R-RNO-416530 FFAR1:FFAR1 ligands activate Gq IEA Rattus norvegicus 42504 R-RNO-444202 https://reactome.org/PathwayBrowser/#/R-RNO-444202 Receptor FFAR1 binds free fatty acids IEA Rattus norvegicus 42504 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 42504 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 42548 R-BTA-6787677 https://reactome.org/PathwayBrowser/#/R-BTA-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Bos taurus 42548 R-CFA-6787677 https://reactome.org/PathwayBrowser/#/R-CFA-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Canis familiaris 42548 R-DRE-6787677 https://reactome.org/PathwayBrowser/#/R-DRE-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Danio rerio 42548 R-HSA-6787677 https://reactome.org/PathwayBrowser/#/R-HSA-6787677 FUOM isomerises alpha-Fuc to beta-Fuc TAS Homo sapiens 42548 R-MMU-6787677 https://reactome.org/PathwayBrowser/#/R-MMU-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Mus musculus 42548 R-RNO-6787677 https://reactome.org/PathwayBrowser/#/R-RNO-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Rattus norvegicus 42548 R-SSC-6787677 https://reactome.org/PathwayBrowser/#/R-SSC-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Sus scrofa 42589 R-BTA-6787540 https://reactome.org/PathwayBrowser/#/R-BTA-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Bos taurus 42589 R-BTA-6787677 https://reactome.org/PathwayBrowser/#/R-BTA-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Bos taurus 42589 R-CEL-6787540 https://reactome.org/PathwayBrowser/#/R-CEL-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Caenorhabditis elegans 42589 R-CFA-6787540 https://reactome.org/PathwayBrowser/#/R-CFA-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Canis familiaris 42589 R-CFA-6787677 https://reactome.org/PathwayBrowser/#/R-CFA-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Canis familiaris 42589 R-DDI-6787540 https://reactome.org/PathwayBrowser/#/R-DDI-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Dictyostelium discoideum 42589 R-DRE-6787677 https://reactome.org/PathwayBrowser/#/R-DRE-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Danio rerio 42589 R-HSA-6787540 https://reactome.org/PathwayBrowser/#/R-HSA-6787540 FUK phosphorylates beta-Fuc to Fuc1P TAS Homo sapiens 42589 R-HSA-6787677 https://reactome.org/PathwayBrowser/#/R-HSA-6787677 FUOM isomerises alpha-Fuc to beta-Fuc TAS Homo sapiens 42589 R-MMU-6787540 https://reactome.org/PathwayBrowser/#/R-MMU-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Mus musculus 42589 R-MMU-6787677 https://reactome.org/PathwayBrowser/#/R-MMU-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Mus musculus 42589 R-RNO-6787540 https://reactome.org/PathwayBrowser/#/R-RNO-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Rattus norvegicus 42589 R-RNO-6787677 https://reactome.org/PathwayBrowser/#/R-RNO-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Rattus norvegicus 42589 R-SSC-6787540 https://reactome.org/PathwayBrowser/#/R-SSC-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Sus scrofa 42589 R-SSC-6787677 https://reactome.org/PathwayBrowser/#/R-SSC-6787677 FUOM isomerises alpha-Fuc to beta-Fuc IEA Sus scrofa 42589 R-XTR-6787540 https://reactome.org/PathwayBrowser/#/R-XTR-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Xenopus tropicalis 4260 R-HSA-9661710 https://reactome.org/PathwayBrowser/#/R-HSA-9661710 An unknown oxidase oxidises D-UBGN to UBN TAS Homo sapiens 4260 R-HSA-9661726 https://reactome.org/PathwayBrowser/#/R-HSA-9661726 An unknown reductase reduces D-UBGN to STBN TAS Homo sapiens 4260 R-HSA-9661745 https://reactome.org/PathwayBrowser/#/R-HSA-9661745 An unknown BILR reduces BIL to D-UBGN TAS Homo sapiens 42638 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 42638 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 42638 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 42638 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 42638 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 42638 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 42638 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 42638 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 42638 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 42638 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 42782 R-BTA-8850356 https://reactome.org/PathwayBrowser/#/R-BTA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Bos taurus 42782 R-GGA-8850356 https://reactome.org/PathwayBrowser/#/R-GGA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Gallus gallus 42782 R-HSA-8850356 https://reactome.org/PathwayBrowser/#/R-HSA-8850356 TCR binds microbial lipid-based antigen via CD1 TAS Homo sapiens 42782 R-SSC-8850356 https://reactome.org/PathwayBrowser/#/R-SSC-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Sus scrofa 42820 R-BTA-434650 https://reactome.org/PathwayBrowser/#/R-BTA-434650 MATEs mediate extrusion of xenobiotics IEA Bos taurus 42820 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 42820 R-BTA-549304 https://reactome.org/PathwayBrowser/#/R-BTA-549304 OCT3 mediates renal clearance of organic cations IEA Bos taurus 42820 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 42820 R-BTA-561072 https://reactome.org/PathwayBrowser/#/R-BTA-561072 OCT3 mediates renal uptake of organic cations IEA Bos taurus 42820 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 42820 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans 42820 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 42820 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans 42820 R-CFA-434650 https://reactome.org/PathwayBrowser/#/R-CFA-434650 MATEs mediate extrusion of xenobiotics IEA Canis familiaris 42820 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 42820 R-CFA-549304 https://reactome.org/PathwayBrowser/#/R-CFA-549304 OCT3 mediates renal clearance of organic cations IEA Canis familiaris 42820 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 42820 R-CFA-561072 https://reactome.org/PathwayBrowser/#/R-CFA-561072 OCT3 mediates renal uptake of organic cations IEA Canis familiaris 42820 R-DDI-434650 https://reactome.org/PathwayBrowser/#/R-DDI-434650 MATEs mediate extrusion of xenobiotics IEA Dictyostelium discoideum 42820 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 42820 R-DME-549304 https://reactome.org/PathwayBrowser/#/R-DME-549304 OCT3 mediates renal clearance of organic cations IEA Drosophila melanogaster 42820 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 42820 R-DME-561072 https://reactome.org/PathwayBrowser/#/R-DME-561072 OCT3 mediates renal uptake of organic cations IEA Drosophila melanogaster 42820 R-DRE-434650 https://reactome.org/PathwayBrowser/#/R-DRE-434650 MATEs mediate extrusion of xenobiotics IEA Danio rerio 42820 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 42820 R-DRE-549304 https://reactome.org/PathwayBrowser/#/R-DRE-549304 OCT3 mediates renal clearance of organic cations IEA Danio rerio 42820 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 42820 R-DRE-561072 https://reactome.org/PathwayBrowser/#/R-DRE-561072 OCT3 mediates renal uptake of organic cations IEA Danio rerio 42820 R-GGA-434650 https://reactome.org/PathwayBrowser/#/R-GGA-434650 MATEs mediate extrusion of xenobiotics IEA Gallus gallus 42820 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 42820 R-GGA-549304 https://reactome.org/PathwayBrowser/#/R-GGA-549304 OCT3 mediates renal clearance of organic cations IEA Gallus gallus 42820 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 42820 R-GGA-561072 https://reactome.org/PathwayBrowser/#/R-GGA-561072 OCT3 mediates renal uptake of organic cations IEA Gallus gallus 42820 R-HSA-434650 https://reactome.org/PathwayBrowser/#/R-HSA-434650 MATEs mediate extrusion of xenobiotics TAS Homo sapiens 42820 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 42820 R-HSA-549304 https://reactome.org/PathwayBrowser/#/R-HSA-549304 OCT3 mediates renal clearance of organic cations TAS Homo sapiens 42820 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 42820 R-HSA-561072 https://reactome.org/PathwayBrowser/#/R-HSA-561072 OCT3 mediates renal uptake of organic cations TAS Homo sapiens 42820 R-MMU-434650 https://reactome.org/PathwayBrowser/#/R-MMU-434650 MATEs mediate extrusion of xenobiotics IEA Mus musculus 42820 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 42820 R-MMU-549304 https://reactome.org/PathwayBrowser/#/R-MMU-549304 OCT3 mediates renal clearance of organic cations IEA Mus musculus 42820 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 42820 R-MMU-561072 https://reactome.org/PathwayBrowser/#/R-MMU-561072 OCT3 mediates renal uptake of organic cations IEA Mus musculus 42820 R-PFA-434650 https://reactome.org/PathwayBrowser/#/R-PFA-434650 MATEs mediate extrusion of xenobiotics IEA Plasmodium falciparum 42820 R-RNO-434650 https://reactome.org/PathwayBrowser/#/R-RNO-434650 MATEs mediate extrusion of xenobiotics IEA Rattus norvegicus 42820 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 42820 R-RNO-549304 https://reactome.org/PathwayBrowser/#/R-RNO-549304 OCT3 mediates renal clearance of organic cations IEA Rattus norvegicus 42820 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 42820 R-RNO-561072 https://reactome.org/PathwayBrowser/#/R-RNO-561072 OCT3 mediates renal uptake of organic cations IEA Rattus norvegicus 42820 R-SCE-434650 https://reactome.org/PathwayBrowser/#/R-SCE-434650 MATEs mediate extrusion of xenobiotics IEA Saccharomyces cerevisiae 42820 R-SPO-434650 https://reactome.org/PathwayBrowser/#/R-SPO-434650 MATEs mediate extrusion of xenobiotics IEA Schizosaccharomyces pombe 42820 R-SSC-434650 https://reactome.org/PathwayBrowser/#/R-SSC-434650 MATEs mediate extrusion of xenobiotics IEA Sus scrofa 42820 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 42820 R-SSC-549304 https://reactome.org/PathwayBrowser/#/R-SSC-549304 OCT3 mediates renal clearance of organic cations IEA Sus scrofa 42820 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 42820 R-SSC-561072 https://reactome.org/PathwayBrowser/#/R-SSC-561072 OCT3 mediates renal uptake of organic cations IEA Sus scrofa 42820 R-XTR-434650 https://reactome.org/PathwayBrowser/#/R-XTR-434650 MATEs mediate extrusion of xenobiotics IEA Xenopus tropicalis 42820 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 42820 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 42944 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 42944 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 42944 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 42944 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 42944 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 42944 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 42944 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 42944 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 42944 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 42944 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 42944 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 42944 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 42944 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 42944 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 42944 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 42976 R-BTA-6804527 https://reactome.org/PathwayBrowser/#/R-BTA-6804527 INTL1 binds bacterial glycans IEA Bos taurus 42976 R-DRE-6804527 https://reactome.org/PathwayBrowser/#/R-DRE-6804527 INTL1 binds bacterial glycans IEA Danio rerio 42976 R-HSA-6804527 https://reactome.org/PathwayBrowser/#/R-HSA-6804527 INTL1 binds bacterial glycans TAS Homo sapiens 42976 R-MMU-6804527 https://reactome.org/PathwayBrowser/#/R-MMU-6804527 INTL1 binds bacterial glycans IEA Mus musculus 42976 R-RNO-6804527 https://reactome.org/PathwayBrowser/#/R-RNO-6804527 INTL1 binds bacterial glycans IEA Rattus norvegicus 42976 R-SSC-6804527 https://reactome.org/PathwayBrowser/#/R-SSC-6804527 INTL1 binds bacterial glycans IEA Sus scrofa 42976 R-XTR-6804527 https://reactome.org/PathwayBrowser/#/R-XTR-6804527 INTL1 binds bacterial glycans IEA Xenopus tropicalis 42977 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 42977 R-BTA-8867667 https://reactome.org/PathwayBrowser/#/R-BTA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Bos taurus 42977 R-BTA-8868402 https://reactome.org/PathwayBrowser/#/R-BTA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Bos taurus 42977 R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 42977 R-CEL-8867667 https://reactome.org/PathwayBrowser/#/R-CEL-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Caenorhabditis elegans 42977 R-CEL-8868402 https://reactome.org/PathwayBrowser/#/R-CEL-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Caenorhabditis elegans 42977 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 42977 R-CFA-8867667 https://reactome.org/PathwayBrowser/#/R-CFA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Canis familiaris 42977 R-CFA-8868402 https://reactome.org/PathwayBrowser/#/R-CFA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Canis familiaris 42977 R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 42977 R-DDI-8867667 https://reactome.org/PathwayBrowser/#/R-DDI-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Dictyostelium discoideum 42977 R-DDI-8868402 https://reactome.org/PathwayBrowser/#/R-DDI-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Dictyostelium discoideum 42977 R-DME-8867667 https://reactome.org/PathwayBrowser/#/R-DME-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Drosophila melanogaster 42977 R-DME-8868402 https://reactome.org/PathwayBrowser/#/R-DME-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Drosophila melanogaster 42977 R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 42977 R-DRE-8867667 https://reactome.org/PathwayBrowser/#/R-DRE-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Danio rerio 42977 R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 42977 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 42977 R-GGA-8867667 https://reactome.org/PathwayBrowser/#/R-GGA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Gallus gallus 42977 R-GGA-8868402 https://reactome.org/PathwayBrowser/#/R-GGA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Gallus gallus 42977 R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 42977 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 42977 R-HSA-5602885 https://reactome.org/PathwayBrowser/#/R-HSA-5602885 Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL TAS Homo sapiens 42977 R-HSA-8867667 https://reactome.org/PathwayBrowser/#/R-HSA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane TAS Homo sapiens 42977 R-HSA-8868402 https://reactome.org/PathwayBrowser/#/R-HSA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane TAS Homo sapiens 42977 R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 42977 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 42977 R-MMU-8867667 https://reactome.org/PathwayBrowser/#/R-MMU-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Mus musculus 42977 R-MMU-8868402 https://reactome.org/PathwayBrowser/#/R-MMU-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Mus musculus 42977 R-PFA-8867667 https://reactome.org/PathwayBrowser/#/R-PFA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Plasmodium falciparum 42977 R-PFA-8868402 https://reactome.org/PathwayBrowser/#/R-PFA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Plasmodium falciparum 42977 R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 42977 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 42977 R-RNO-8867667 https://reactome.org/PathwayBrowser/#/R-RNO-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Rattus norvegicus 42977 R-RNO-8868402 https://reactome.org/PathwayBrowser/#/R-RNO-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Rattus norvegicus 42977 R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 42977 R-SCE-8867667 https://reactome.org/PathwayBrowser/#/R-SCE-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Saccharomyces cerevisiae 42977 R-SCE-8868402 https://reactome.org/PathwayBrowser/#/R-SCE-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Saccharomyces cerevisiae 42977 R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 42977 R-SPO-8867667 https://reactome.org/PathwayBrowser/#/R-SPO-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Schizosaccharomyces pombe 42977 R-SPO-8868402 https://reactome.org/PathwayBrowser/#/R-SPO-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Schizosaccharomyces pombe 42977 R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 42977 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 42977 R-SSC-8867667 https://reactome.org/PathwayBrowser/#/R-SSC-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Sus scrofa 42977 R-SSC-8868402 https://reactome.org/PathwayBrowser/#/R-SSC-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Sus scrofa 42977 R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 42977 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 42977 R-XTR-8867667 https://reactome.org/PathwayBrowser/#/R-XTR-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Xenopus tropicalis 4299 R-HSA-5657651 https://reactome.org/PathwayBrowser/#/R-HSA-5657651 MGMT binds alkylated DNA containing 6-O-methylguanine TAS Homo sapiens 4299 R-HSA-73892 https://reactome.org/PathwayBrowser/#/R-HSA-73892 MGMT/hAGT mediated DNA Damage Reversal TAS Homo sapiens 4299 R-HSA-9732692 https://reactome.org/PathwayBrowser/#/R-HSA-9732692 Triazenes produce DNA damage in the form of O6-methylguanine IEA Homo sapiens 4299 R-MMU-9749883 https://reactome.org/PathwayBrowser/#/R-MMU-9749883 Temozolomide produces DNA damage in the form of O6-methylguanine in mouse dsDNA TAS Mus musculus 43074 R-BTA-191323 https://reactome.org/PathwayBrowser/#/R-BTA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Bos taurus 43074 R-BTA-191352 https://reactome.org/PathwayBrowser/#/R-BTA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Bos taurus 43074 R-BTA-6788597 https://reactome.org/PathwayBrowser/#/R-BTA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Bos taurus 43074 R-BTA-70785 https://reactome.org/PathwayBrowser/#/R-BTA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Bos taurus 43074 R-CEL-191323 https://reactome.org/PathwayBrowser/#/R-CEL-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Caenorhabditis elegans 43074 R-CEL-191352 https://reactome.org/PathwayBrowser/#/R-CEL-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Caenorhabditis elegans 43074 R-CEL-6788597 https://reactome.org/PathwayBrowser/#/R-CEL-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Caenorhabditis elegans 43074 R-CEL-70785 https://reactome.org/PathwayBrowser/#/R-CEL-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Caenorhabditis elegans 43074 R-CFA-191323 https://reactome.org/PathwayBrowser/#/R-CFA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Canis familiaris 43074 R-CFA-191352 https://reactome.org/PathwayBrowser/#/R-CFA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Canis familiaris 43074 R-CFA-6788597 https://reactome.org/PathwayBrowser/#/R-CFA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Canis familiaris 43074 R-CFA-70785 https://reactome.org/PathwayBrowser/#/R-CFA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Canis familiaris 43074 R-DDI-191323 https://reactome.org/PathwayBrowser/#/R-DDI-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Dictyostelium discoideum 43074 R-DDI-191352 https://reactome.org/PathwayBrowser/#/R-DDI-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Dictyostelium discoideum 43074 R-DDI-6788597 https://reactome.org/PathwayBrowser/#/R-DDI-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Dictyostelium discoideum 43074 R-DDI-70785 https://reactome.org/PathwayBrowser/#/R-DDI-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Dictyostelium discoideum 43074 R-DME-191323 https://reactome.org/PathwayBrowser/#/R-DME-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Drosophila melanogaster 43074 R-DME-191352 https://reactome.org/PathwayBrowser/#/R-DME-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Drosophila melanogaster 43074 R-DME-6788597 https://reactome.org/PathwayBrowser/#/R-DME-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Drosophila melanogaster 43074 R-DME-70785 https://reactome.org/PathwayBrowser/#/R-DME-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Drosophila melanogaster 43074 R-DRE-191352 https://reactome.org/PathwayBrowser/#/R-DRE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Danio rerio 43074 R-DRE-6788597 https://reactome.org/PathwayBrowser/#/R-DRE-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Danio rerio 43074 R-GGA-191323 https://reactome.org/PathwayBrowser/#/R-GGA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Gallus gallus 43074 R-GGA-191352 https://reactome.org/PathwayBrowser/#/R-GGA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Gallus gallus 43074 R-GGA-6788597 https://reactome.org/PathwayBrowser/#/R-GGA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Gallus gallus 43074 R-GGA-70785 https://reactome.org/PathwayBrowser/#/R-GGA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Gallus gallus 43074 R-HSA-191323 https://reactome.org/PathwayBrowser/#/R-HSA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA TAS Homo sapiens 43074 R-HSA-191352 https://reactome.org/PathwayBrowser/#/R-HSA-191352 HMGCR dimer reduces bHMG-CoA to MVA TAS Homo sapiens 43074 R-HSA-6788597 https://reactome.org/PathwayBrowser/#/R-HSA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA TAS Homo sapiens 43074 R-HSA-70785 https://reactome.org/PathwayBrowser/#/R-HSA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA TAS Homo sapiens 43074 R-MMU-191323 https://reactome.org/PathwayBrowser/#/R-MMU-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Mus musculus 43074 R-MMU-191352 https://reactome.org/PathwayBrowser/#/R-MMU-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Mus musculus 43074 R-MMU-6788597 https://reactome.org/PathwayBrowser/#/R-MMU-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Mus musculus 43074 R-MMU-70785 https://reactome.org/PathwayBrowser/#/R-MMU-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Mus musculus 43074 R-PFA-70785 https://reactome.org/PathwayBrowser/#/R-PFA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Plasmodium falciparum 43074 R-RNO-191323 https://reactome.org/PathwayBrowser/#/R-RNO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Rattus norvegicus 43074 R-RNO-191352 https://reactome.org/PathwayBrowser/#/R-RNO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Rattus norvegicus 43074 R-RNO-6788597 https://reactome.org/PathwayBrowser/#/R-RNO-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Rattus norvegicus 43074 R-RNO-70785 https://reactome.org/PathwayBrowser/#/R-RNO-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Rattus norvegicus 43074 R-SCE-191323 https://reactome.org/PathwayBrowser/#/R-SCE-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Saccharomyces cerevisiae 43074 R-SCE-191352 https://reactome.org/PathwayBrowser/#/R-SCE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Saccharomyces cerevisiae 43074 R-SPO-191323 https://reactome.org/PathwayBrowser/#/R-SPO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Schizosaccharomyces pombe 43074 R-SPO-191352 https://reactome.org/PathwayBrowser/#/R-SPO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Schizosaccharomyces pombe 43074 R-SSC-191323 https://reactome.org/PathwayBrowser/#/R-SSC-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Sus scrofa 43074 R-SSC-191352 https://reactome.org/PathwayBrowser/#/R-SSC-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Sus scrofa 43074 R-SSC-6788597 https://reactome.org/PathwayBrowser/#/R-SSC-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Sus scrofa 43074 R-SSC-70785 https://reactome.org/PathwayBrowser/#/R-SSC-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Sus scrofa 43074 R-XTR-191352 https://reactome.org/PathwayBrowser/#/R-XTR-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Xenopus tropicalis 43074 R-XTR-6788597 https://reactome.org/PathwayBrowser/#/R-XTR-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Xenopus tropicalis 43074 R-XTR-70785 https://reactome.org/PathwayBrowser/#/R-XTR-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Xenopus tropicalis 4325 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 4325 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 4325 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 4325 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 4325 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 4325 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 4325 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 4325 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 4325 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 4325 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 43263 R-HSA-6786257 https://reactome.org/PathwayBrowser/#/R-HSA-6786257 DCTPP1 hydrolyses 5idCTP IEA Homo sapiens 43263 R-MMU-6786295 https://reactome.org/PathwayBrowser/#/R-MMU-6786295 Dctpp1 hydrolyses 5idCTP TAS Mus musculus 43451 R-BTA-209815 https://reactome.org/PathwayBrowser/#/R-BTA-209815 Tyrosine is monoiodinated IEA Bos taurus 43451 R-CEL-209815 https://reactome.org/PathwayBrowser/#/R-CEL-209815 Tyrosine is monoiodinated IEA Caenorhabditis elegans 43451 R-CFA-209815 https://reactome.org/PathwayBrowser/#/R-CFA-209815 Tyrosine is monoiodinated IEA Canis familiaris 43451 R-DDI-209815 https://reactome.org/PathwayBrowser/#/R-DDI-209815 Tyrosine is monoiodinated IEA Dictyostelium discoideum 43451 R-DME-209815 https://reactome.org/PathwayBrowser/#/R-DME-209815 Tyrosine is monoiodinated IEA Drosophila melanogaster 43451 R-GGA-209815 https://reactome.org/PathwayBrowser/#/R-GGA-209815 Tyrosine is monoiodinated IEA Gallus gallus 43451 R-HSA-209815 https://reactome.org/PathwayBrowser/#/R-HSA-209815 Tyrosine is monoiodinated TAS Homo sapiens 43451 R-MMU-209815 https://reactome.org/PathwayBrowser/#/R-MMU-209815 Tyrosine is monoiodinated IEA Mus musculus 43451 R-RNO-209815 https://reactome.org/PathwayBrowser/#/R-RNO-209815 Tyrosine is monoiodinated IEA Rattus norvegicus 43451 R-SSC-209815 https://reactome.org/PathwayBrowser/#/R-SSC-209815 Tyrosine is monoiodinated IEA Sus scrofa 43474 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 43474 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 43474 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 43474 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 43474 R-BTA-109415 https://reactome.org/PathwayBrowser/#/R-BTA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Bos taurus 43474 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 43474 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 43474 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 43474 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 43474 R-BTA-111215 https://reactome.org/PathwayBrowser/#/R-BTA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Bos taurus 43474 R-BTA-111524 https://reactome.org/PathwayBrowser/#/R-BTA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Bos taurus 43474 R-BTA-112033 https://reactome.org/PathwayBrowser/#/R-BTA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Bos taurus 43474 R-BTA-112034 https://reactome.org/PathwayBrowser/#/R-BTA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Bos taurus 43474 R-BTA-112037 https://reactome.org/PathwayBrowser/#/R-BTA-112037 Inactivation of PLC beta IEA Bos taurus 43474 R-BTA-113503 https://reactome.org/PathwayBrowser/#/R-BTA-113503 PP2A mediated localization of RB1 protein in chromatin IEA Bos taurus 43474 R-BTA-1169192 https://reactome.org/PathwayBrowser/#/R-BTA-1169192 PTP1B dephosphorylates GHR IEA Bos taurus 43474 R-BTA-1237129 https://reactome.org/PathwayBrowser/#/R-BTA-1237129 Acireductone is created IEA Bos taurus 43474 R-BTA-1237160 https://reactome.org/PathwayBrowser/#/R-BTA-1237160 MTA is cleaved and phosphorylated IEA Bos taurus 43474 R-BTA-1247935 https://reactome.org/PathwayBrowser/#/R-BTA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Bos taurus 43474 R-BTA-1295632 https://reactome.org/PathwayBrowser/#/R-BTA-1295632 PPA2A dephosphorylates SPRY2 IEA Bos taurus 43474 R-BTA-1363274 https://reactome.org/PathwayBrowser/#/R-BTA-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Bos taurus 43474 R-BTA-1363276 https://reactome.org/PathwayBrowser/#/R-BTA-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Bos taurus 43474 R-BTA-1369065 https://reactome.org/PathwayBrowser/#/R-BTA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Bos taurus 43474 R-BTA-139906 https://reactome.org/PathwayBrowser/#/R-BTA-139906 Activation of BAD by calcineurin IEA Bos taurus 43474 R-BTA-1454916 https://reactome.org/PathwayBrowser/#/R-BTA-1454916 The ABCC family mediates organic anion transport IEA Bos taurus 43474 R-BTA-1454928 https://reactome.org/PathwayBrowser/#/R-BTA-1454928 ABCG4 may mediate cholesterol efflux IEA Bos taurus 43474 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-1467466 https://reactome.org/PathwayBrowser/#/R-BTA-1467466 ABCA4 mediates atRAL transport IEA Bos taurus 43474 R-BTA-1483096 https://reactome.org/PathwayBrowser/#/R-BTA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Bos taurus 43474 R-BTA-1483159 https://reactome.org/PathwayBrowser/#/R-BTA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Bos taurus 43474 R-BTA-1483203 https://reactome.org/PathwayBrowser/#/R-BTA-1483203 PA is dephosphorylated to DAG by LPIN IEA Bos taurus 43474 R-BTA-159101 https://reactome.org/PathwayBrowser/#/R-BTA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Bos taurus 43474 R-BTA-163120 https://reactome.org/PathwayBrowser/#/R-BTA-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Bos taurus 43474 R-BTA-1638821 https://reactome.org/PathwayBrowser/#/R-BTA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Bos taurus 43474 R-BTA-164832 https://reactome.org/PathwayBrowser/#/R-BTA-164832 ATPase synthesizes ATP IEA Bos taurus 43474 R-BTA-164840 https://reactome.org/PathwayBrowser/#/R-BTA-164840 ADP and Pi bind to ATPase IEA Bos taurus 43474 R-BTA-1675795 https://reactome.org/PathwayBrowser/#/R-BTA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Bos taurus 43474 R-BTA-1675824 https://reactome.org/PathwayBrowser/#/R-BTA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Bos taurus 43474 R-BTA-1675836 https://reactome.org/PathwayBrowser/#/R-BTA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Bos taurus 43474 R-BTA-1675949 https://reactome.org/PathwayBrowser/#/R-BTA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Bos taurus 43474 R-BTA-1675988 https://reactome.org/PathwayBrowser/#/R-BTA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Bos taurus 43474 R-BTA-1675994 https://reactome.org/PathwayBrowser/#/R-BTA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Bos taurus 43474 R-BTA-1676005 https://reactome.org/PathwayBrowser/#/R-BTA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Bos taurus 43474 R-BTA-1676020 https://reactome.org/PathwayBrowser/#/R-BTA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Bos taurus 43474 R-BTA-1676065 https://reactome.org/PathwayBrowser/#/R-BTA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Bos taurus 43474 R-BTA-1676105 https://reactome.org/PathwayBrowser/#/R-BTA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Bos taurus 43474 R-BTA-1676114 https://reactome.org/PathwayBrowser/#/R-BTA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Bos taurus 43474 R-BTA-1676124 https://reactome.org/PathwayBrowser/#/R-BTA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Bos taurus 43474 R-BTA-1676133 https://reactome.org/PathwayBrowser/#/R-BTA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Bos taurus 43474 R-BTA-1676141 https://reactome.org/PathwayBrowser/#/R-BTA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Bos taurus 43474 R-BTA-1676149 https://reactome.org/PathwayBrowser/#/R-BTA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Bos taurus 43474 R-BTA-1676162 https://reactome.org/PathwayBrowser/#/R-BTA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Bos taurus 43474 R-BTA-1676164 https://reactome.org/PathwayBrowser/#/R-BTA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Bos taurus 43474 R-BTA-1676174 https://reactome.org/PathwayBrowser/#/R-BTA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Bos taurus 43474 R-BTA-1676177 https://reactome.org/PathwayBrowser/#/R-BTA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Bos taurus 43474 R-BTA-1676203 https://reactome.org/PathwayBrowser/#/R-BTA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Bos taurus 43474 R-BTA-1676204 https://reactome.org/PathwayBrowser/#/R-BTA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Bos taurus 43474 R-BTA-170153 https://reactome.org/PathwayBrowser/#/R-BTA-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Bos taurus 43474 R-BTA-170158 https://reactome.org/PathwayBrowser/#/R-BTA-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Bos taurus 43474 R-BTA-170161 https://reactome.org/PathwayBrowser/#/R-BTA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Bos taurus 43474 R-BTA-170666 https://reactome.org/PathwayBrowser/#/R-BTA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Bos taurus 43474 R-BTA-170685 https://reactome.org/PathwayBrowser/#/R-BTA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Bos taurus 43474 R-BTA-170686 https://reactome.org/PathwayBrowser/#/R-BTA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Bos taurus 43474 R-BTA-174110 https://reactome.org/PathwayBrowser/#/R-BTA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Bos taurus 43474 R-BTA-174367 https://reactome.org/PathwayBrowser/#/R-BTA-174367 GCL ligates L-Glu to L-Cys IEA Bos taurus 43474 R-BTA-174391 https://reactome.org/PathwayBrowser/#/R-BTA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Bos taurus 43474 R-BTA-174394 https://reactome.org/PathwayBrowser/#/R-BTA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Bos taurus 43474 R-BTA-174438 https://reactome.org/PathwayBrowser/#/R-BTA-174438 Formation of the Flap Intermediate on the C-strand IEA Bos taurus 43474 R-BTA-174439 https://reactome.org/PathwayBrowser/#/R-BTA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Bos taurus 43474 R-BTA-176606 https://reactome.org/PathwayBrowser/#/R-BTA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Bos taurus 43474 R-BTA-177923 https://reactome.org/PathwayBrowser/#/R-BTA-177923 Sustained activation of SRC kinase by SHP2 IEA Bos taurus 43474 R-BTA-177924 https://reactome.org/PathwayBrowser/#/R-BTA-177924 Dephosphorylation of Gab1 by SHP2 IEA Bos taurus 43474 R-BTA-177926 https://reactome.org/PathwayBrowser/#/R-BTA-177926 Dephosphorylation of PAG by SHP2 IEA Bos taurus 43474 R-BTA-177935 https://reactome.org/PathwayBrowser/#/R-BTA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Bos taurus 43474 R-BTA-1855154 https://reactome.org/PathwayBrowser/#/R-BTA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 43474 R-BTA-1855159 https://reactome.org/PathwayBrowser/#/R-BTA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Bos taurus 43474 R-BTA-1855163 https://reactome.org/PathwayBrowser/#/R-BTA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Bos taurus 43474 R-BTA-1855165 https://reactome.org/PathwayBrowser/#/R-BTA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 43474 R-BTA-1855166 https://reactome.org/PathwayBrowser/#/R-BTA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Bos taurus 43474 R-BTA-1855171 https://reactome.org/PathwayBrowser/#/R-BTA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Bos taurus 43474 R-BTA-1855174 https://reactome.org/PathwayBrowser/#/R-BTA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Bos taurus 43474 R-BTA-1855180 https://reactome.org/PathwayBrowser/#/R-BTA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Bos taurus 43474 R-BTA-1855198 https://reactome.org/PathwayBrowser/#/R-BTA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 43474 R-BTA-1855200 https://reactome.org/PathwayBrowser/#/R-BTA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Bos taurus 43474 R-BTA-1855202 https://reactome.org/PathwayBrowser/#/R-BTA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Bos taurus 43474 R-BTA-1855205 https://reactome.org/PathwayBrowser/#/R-BTA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Bos taurus 43474 R-BTA-1855208 https://reactome.org/PathwayBrowser/#/R-BTA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Bos taurus 43474 R-BTA-1855210 https://reactome.org/PathwayBrowser/#/R-BTA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 43474 R-BTA-1855211 https://reactome.org/PathwayBrowser/#/R-BTA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 43474 R-BTA-1855213 https://reactome.org/PathwayBrowser/#/R-BTA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Bos taurus 43474 R-BTA-1855218 https://reactome.org/PathwayBrowser/#/R-BTA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Bos taurus 43474 R-BTA-1855219 https://reactome.org/PathwayBrowser/#/R-BTA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Bos taurus 43474 R-BTA-1855222 https://reactome.org/PathwayBrowser/#/R-BTA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Bos taurus 43474 R-BTA-1855225 https://reactome.org/PathwayBrowser/#/R-BTA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Bos taurus 43474 R-BTA-1855232 https://reactome.org/PathwayBrowser/#/R-BTA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Bos taurus 43474 R-BTA-1861595 https://reactome.org/PathwayBrowser/#/R-BTA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Bos taurus 43474 R-BTA-191414 https://reactome.org/PathwayBrowser/#/R-BTA-191414 MVD decarboxylates MVA5PP to IPPP IEA Bos taurus 43474 R-BTA-193362 https://reactome.org/PathwayBrowser/#/R-BTA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-194153 https://reactome.org/PathwayBrowser/#/R-BTA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-196950 https://reactome.org/PathwayBrowser/#/R-BTA-196950 2xTRAP hydrolyzes FMN to RIB IEA Bos taurus 43474 R-BTA-197958 https://reactome.org/PathwayBrowser/#/R-BTA-197958 FPGS-2 transforms THF to THFPG IEA Bos taurus 43474 R-BTA-198513 https://reactome.org/PathwayBrowser/#/R-BTA-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Bos taurus 43474 R-BTA-199456 https://reactome.org/PathwayBrowser/#/R-BTA-199456 PTEN dephosphorylates PIP3 IEA Bos taurus 43474 R-BTA-199959 https://reactome.org/PathwayBrowser/#/R-BTA-199959 ERKs are inactivated by protein phosphatase 2A IEA Bos taurus 43474 R-BTA-200555 https://reactome.org/PathwayBrowser/#/R-BTA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Bos taurus 43474 R-BTA-200681 https://reactome.org/PathwayBrowser/#/R-BTA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Bos taurus 43474 R-BTA-200682 https://reactome.org/PathwayBrowser/#/R-BTA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Bos taurus 43474 R-BTA-200711 https://reactome.org/PathwayBrowser/#/R-BTA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Bos taurus 43474 R-BTA-201790 https://reactome.org/PathwayBrowser/#/R-BTA-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Bos taurus 43474 R-BTA-202214 https://reactome.org/PathwayBrowser/#/R-BTA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Bos taurus 43474 R-BTA-202237 https://reactome.org/PathwayBrowser/#/R-BTA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Bos taurus 43474 R-BTA-2023971 https://reactome.org/PathwayBrowser/#/R-BTA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 43474 R-BTA-2023973 https://reactome.org/PathwayBrowser/#/R-BTA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 43474 R-BTA-2029468 https://reactome.org/PathwayBrowser/#/R-BTA-2029468 Conversion of PA into DAG by PAP-1 IEA Bos taurus 43474 R-BTA-2029476 https://reactome.org/PathwayBrowser/#/R-BTA-2029476 Role of myosins in phagosome formation IEA Bos taurus 43474 R-BTA-203797 https://reactome.org/PathwayBrowser/#/R-BTA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Bos taurus 43474 R-BTA-203973 https://reactome.org/PathwayBrowser/#/R-BTA-203973 Vesicle budding IEA Bos taurus 43474 R-BTA-204169 https://reactome.org/PathwayBrowser/#/R-BTA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Bos taurus 43474 R-BTA-2046093 https://reactome.org/PathwayBrowser/#/R-BTA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Bos taurus 43474 R-BTA-209055 https://reactome.org/PathwayBrowser/#/R-BTA-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Bos taurus 43474 R-BTA-2130641 https://reactome.org/PathwayBrowser/#/R-BTA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Bos taurus 43474 R-BTA-2130725 https://reactome.org/PathwayBrowser/#/R-BTA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Bos taurus 43474 R-BTA-216723 https://reactome.org/PathwayBrowser/#/R-BTA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Bos taurus 43474 R-BTA-216757 https://reactome.org/PathwayBrowser/#/R-BTA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Bos taurus 43474 R-BTA-2187401 https://reactome.org/PathwayBrowser/#/R-BTA-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Bos taurus 43474 R-BTA-2395873 https://reactome.org/PathwayBrowser/#/R-BTA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Bos taurus 43474 R-BTA-2395876 https://reactome.org/PathwayBrowser/#/R-BTA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 43474 R-BTA-2395879 https://reactome.org/PathwayBrowser/#/R-BTA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 43474 R-BTA-2395965 https://reactome.org/PathwayBrowser/#/R-BTA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Bos taurus 43474 R-BTA-2408551 https://reactome.org/PathwayBrowser/#/R-BTA-2408551 SeMet is converted to AdoSeMet by MAT IEA Bos taurus 43474 R-BTA-2466767 https://reactome.org/PathwayBrowser/#/R-BTA-2466767 NRPE is a substrate for Abca4 TAS Bos taurus 43474 R-BTA-2509793 https://reactome.org/PathwayBrowser/#/R-BTA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Bos taurus 43474 R-BTA-2509816 https://reactome.org/PathwayBrowser/#/R-BTA-2509816 NUDT16 hydrolyses IDP to IMP IEA Bos taurus 43474 R-BTA-2529015 https://reactome.org/PathwayBrowser/#/R-BTA-2529015 Dephosphorylation of CK2-modified condensin I IEA Bos taurus 43474 R-BTA-2584246 https://reactome.org/PathwayBrowser/#/R-BTA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Bos taurus 43474 R-BTA-265783 https://reactome.org/PathwayBrowser/#/R-BTA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-266082 https://reactome.org/PathwayBrowser/#/R-BTA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Bos taurus 43474 R-BTA-2730849 https://reactome.org/PathwayBrowser/#/R-BTA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Bos taurus 43474 R-BTA-2872498 https://reactome.org/PathwayBrowser/#/R-BTA-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Bos taurus 43474 R-BTA-2995388 https://reactome.org/PathwayBrowser/#/R-BTA-2995388 PP2A dephosphorylates BANF1 IEA Bos taurus 43474 R-BTA-3002811 https://reactome.org/PathwayBrowser/#/R-BTA-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Bos taurus 43474 R-BTA-3095901 https://reactome.org/PathwayBrowser/#/R-BTA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Bos taurus 43474 R-BTA-3257122 https://reactome.org/PathwayBrowser/#/R-BTA-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Bos taurus 43474 R-BTA-3262512 https://reactome.org/PathwayBrowser/#/R-BTA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Bos taurus 43474 R-BTA-3266566 https://reactome.org/PathwayBrowser/#/R-BTA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Bos taurus 43474 R-BTA-3371422 https://reactome.org/PathwayBrowser/#/R-BTA-3371422 ATP hydrolysis by HSP70 IEA Bos taurus 43474 R-BTA-372843 https://reactome.org/PathwayBrowser/#/R-BTA-372843 SLC25A10 mediates exchange of malate and phosphate IEA Bos taurus 43474 R-BTA-377643 https://reactome.org/PathwayBrowser/#/R-BTA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Bos taurus 43474 R-BTA-3781011 https://reactome.org/PathwayBrowser/#/R-BTA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Bos taurus 43474 R-BTA-3781018 https://reactome.org/PathwayBrowser/#/R-BTA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Bos taurus 43474 R-BTA-380949 https://reactome.org/PathwayBrowser/#/R-BTA-380949 AMPK is dephosphorylated IEA Bos taurus 43474 R-BTA-380979 https://reactome.org/PathwayBrowser/#/R-BTA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Bos taurus 43474 R-BTA-382560 https://reactome.org/PathwayBrowser/#/R-BTA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Bos taurus 43474 R-BTA-382575 https://reactome.org/PathwayBrowser/#/R-BTA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Bos taurus 43474 R-BTA-383190 https://reactome.org/PathwayBrowser/#/R-BTA-383190 HCO3- transport through ion channel IEA Bos taurus 43474 R-BTA-390593 https://reactome.org/PathwayBrowser/#/R-BTA-390593 ATP Hydrolysis By Myosin IEA Bos taurus 43474 R-BTA-391533 https://reactome.org/PathwayBrowser/#/R-BTA-391533 Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E:Cofactor C-> Beta-tubulin:GDP :alpha-tubulin:GTP heterodimer +Cofactor E+ Cofactor D+ Cofactor C+ Pi TAS Bos taurus 43474 R-BTA-4084976 https://reactome.org/PathwayBrowser/#/R-BTA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Bos taurus 43474 R-BTA-4084989 https://reactome.org/PathwayBrowser/#/R-BTA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Bos taurus 43474 R-BTA-4088141 https://reactome.org/PathwayBrowser/#/R-BTA-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Bos taurus 43474 R-BTA-4093339 https://reactome.org/PathwayBrowser/#/R-BTA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Bos taurus 43474 R-BTA-416320 https://reactome.org/PathwayBrowser/#/R-BTA-416320 Trafficking of GluR1-containing AMPA receptors IEA Bos taurus 43474 R-BTA-416546 https://reactome.org/PathwayBrowser/#/R-BTA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Bos taurus 43474 R-BTA-416559 https://reactome.org/PathwayBrowser/#/R-BTA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Bos taurus 43474 R-BTA-416639 https://reactome.org/PathwayBrowser/#/R-BTA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Bos taurus 43474 R-BTA-416985 https://reactome.org/PathwayBrowser/#/R-BTA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Bos taurus 43474 R-BTA-421007 https://reactome.org/PathwayBrowser/#/R-BTA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Bos taurus 43474 R-BTA-421831 https://reactome.org/PathwayBrowser/#/R-BTA-421831 trans-Golgi Network Coat Assembly IEA Bos taurus 43474 R-BTA-421835 https://reactome.org/PathwayBrowser/#/R-BTA-421835 trans-Golgi Network Vesicle Scission IEA Bos taurus 43474 R-BTA-427605 https://reactome.org/PathwayBrowser/#/R-BTA-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Bos taurus 43474 R-BTA-427645 https://reactome.org/PathwayBrowser/#/R-BTA-427645 SLC34A3 cotransports Pi, 2Na+ IEA Bos taurus 43474 R-BTA-427656 https://reactome.org/PathwayBrowser/#/R-BTA-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Bos taurus 43474 R-BTA-428609 https://reactome.org/PathwayBrowser/#/R-BTA-428609 Type I Na+-coupled phosphate co-transport IEA Bos taurus 43474 R-BTA-428664 https://reactome.org/PathwayBrowser/#/R-BTA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Bos taurus 43474 R-BTA-428690 https://reactome.org/PathwayBrowser/#/R-BTA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Bos taurus 43474 R-BTA-428696 https://reactome.org/PathwayBrowser/#/R-BTA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Bos taurus 43474 R-BTA-429157 https://reactome.org/PathwayBrowser/#/R-BTA-429157 ABCC4 accumulation of dense granule contents IEA Bos taurus 43474 R-BTA-429730 https://reactome.org/PathwayBrowser/#/R-BTA-429730 PPM1L dephosphorylates multiphospho-CERT1-2 IEA Bos taurus 43474 R-BTA-432706 https://reactome.org/PathwayBrowser/#/R-BTA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Bos taurus 43474 R-BTA-432707 https://reactome.org/PathwayBrowser/#/R-BTA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Bos taurus 43474 R-BTA-4419948 https://reactome.org/PathwayBrowser/#/R-BTA-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Bos taurus 43474 R-BTA-445699 https://reactome.org/PathwayBrowser/#/R-BTA-445699 ATP Hydrolysis By Myosin IEA Bos taurus 43474 R-BTA-446200 https://reactome.org/PathwayBrowser/#/R-BTA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Bos taurus 43474 R-BTA-449937 https://reactome.org/PathwayBrowser/#/R-BTA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Bos taurus 43474 R-BTA-453339 https://reactome.org/PathwayBrowser/#/R-BTA-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Bos taurus 43474 R-BTA-4551451 https://reactome.org/PathwayBrowser/#/R-BTA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Bos taurus 43474 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 43474 R-BTA-504054 https://reactome.org/PathwayBrowser/#/R-BTA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Bos taurus 43474 R-BTA-508040 https://reactome.org/PathwayBrowser/#/R-BTA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Bos taurus 43474 R-BTA-508308 https://reactome.org/PathwayBrowser/#/R-BTA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Bos taurus 43474 R-BTA-5221130 https://reactome.org/PathwayBrowser/#/R-BTA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Bos taurus 43474 R-BTA-5223313 https://reactome.org/PathwayBrowser/#/R-BTA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Bos taurus 43474 R-BTA-5223317 https://reactome.org/PathwayBrowser/#/R-BTA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Bos taurus 43474 R-BTA-5251955 https://reactome.org/PathwayBrowser/#/R-BTA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Bos taurus 43474 R-BTA-5251959 https://reactome.org/PathwayBrowser/#/R-BTA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Bos taurus 43474 R-BTA-5251989 https://reactome.org/PathwayBrowser/#/R-BTA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Bos taurus 43474 R-BTA-5419271 https://reactome.org/PathwayBrowser/#/R-BTA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Bos taurus 43474 R-BTA-5419273 https://reactome.org/PathwayBrowser/#/R-BTA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Bos taurus 43474 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 43474 R-BTA-5432421 https://reactome.org/PathwayBrowser/#/R-BTA-5432421 39S subunit binds 28S subunit:mRNA:fMet-tRNA TAS Bos taurus 43474 R-BTA-5432422 https://reactome.org/PathwayBrowser/#/R-BTA-5432422 Translocation of 55S ribosome by 3 bases in the 3' direction TAS Bos taurus 43474 R-BTA-555065 https://reactome.org/PathwayBrowser/#/R-BTA-555065 Formation of clathrin coated vesicle IEA Bos taurus 43474 R-BTA-5603114 https://reactome.org/PathwayBrowser/#/R-BTA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Bos taurus 43474 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 43474 R-BTA-5623513 https://reactome.org/PathwayBrowser/#/R-BTA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Bos taurus 43474 R-BTA-5628905 https://reactome.org/PathwayBrowser/#/R-BTA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Bos taurus 43474 R-BTA-5649705 https://reactome.org/PathwayBrowser/#/R-BTA-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Bos taurus 43474 R-BTA-5665809 https://reactome.org/PathwayBrowser/#/R-BTA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Bos taurus 43474 R-BTA-5672957 https://reactome.org/PathwayBrowser/#/R-BTA-5672957 PP2A dephosphorylates KSR1 IEA Bos taurus 43474 R-BTA-5672961 https://reactome.org/PathwayBrowser/#/R-BTA-5672961 PP2A dephosphorylates inactive RAFs IEA Bos taurus 43474 R-BTA-5675373 https://reactome.org/PathwayBrowser/#/R-BTA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Bos taurus 43474 R-BTA-5675376 https://reactome.org/PathwayBrowser/#/R-BTA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Bos taurus 43474 R-BTA-5675431 https://reactome.org/PathwayBrowser/#/R-BTA-5675431 PP2A dephosphorylates RAF1 IEA Bos taurus 43474 R-BTA-5675433 https://reactome.org/PathwayBrowser/#/R-BTA-5675433 PP5 dephosphorylates RAF1 S338 IEA Bos taurus 43474 R-BTA-5678706 https://reactome.org/PathwayBrowser/#/R-BTA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Bos taurus 43474 R-BTA-5678863 https://reactome.org/PathwayBrowser/#/R-BTA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-5679041 https://reactome.org/PathwayBrowser/#/R-BTA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-5682285 https://reactome.org/PathwayBrowser/#/R-BTA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-5683405 https://reactome.org/PathwayBrowser/#/R-BTA-5683405 PPP5C dephosphorylates TP53BP1 IEA Bos taurus 43474 R-BTA-5683714 https://reactome.org/PathwayBrowser/#/R-BTA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Bos taurus 43474 R-BTA-5683925 https://reactome.org/PathwayBrowser/#/R-BTA-5683925 ULK1 is dephosphorylated IEA Bos taurus 43474 R-BTA-5683967 https://reactome.org/PathwayBrowser/#/R-BTA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Bos taurus 43474 R-BTA-5687758 https://reactome.org/PathwayBrowser/#/R-BTA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Bos taurus 43474 R-BTA-5690996 https://reactome.org/PathwayBrowser/#/R-BTA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Bos taurus 43474 R-BTA-5692462 https://reactome.org/PathwayBrowser/#/R-BTA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Bos taurus 43474 R-BTA-5692480 https://reactome.org/PathwayBrowser/#/R-BTA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Bos taurus 43474 R-BTA-5692754 https://reactome.org/PathwayBrowser/#/R-BTA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Bos taurus 43474 R-BTA-5693153 https://reactome.org/PathwayBrowser/#/R-BTA-5693153 PPM1K dephosphorylates p-BCKDH IEA Bos taurus 43474 R-BTA-5694126 https://reactome.org/PathwayBrowser/#/R-BTA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Bos taurus 43474 R-BTA-5694421 https://reactome.org/PathwayBrowser/#/R-BTA-5694421 PP6 dephosphorylates SEC24 IEA Bos taurus 43474 R-BTA-5694425 https://reactome.org/PathwayBrowser/#/R-BTA-5694425 NSF ATPase activity dissociates cis-SNARE IEA Bos taurus 43474 R-BTA-5694527 https://reactome.org/PathwayBrowser/#/R-BTA-5694527 Loss of SAR1B GTPase IEA Bos taurus 43474 R-BTA-5696408 https://reactome.org/PathwayBrowser/#/R-BTA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Bos taurus 43474 R-BTA-5696415 https://reactome.org/PathwayBrowser/#/R-BTA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Bos taurus 43474 R-BTA-5696839 https://reactome.org/PathwayBrowser/#/R-BTA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Bos taurus 43474 R-BTA-6782131 https://reactome.org/PathwayBrowser/#/R-BTA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Bos taurus 43474 R-BTA-6786245 https://reactome.org/PathwayBrowser/#/R-BTA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Bos taurus 43474 R-BTA-6788295 https://reactome.org/PathwayBrowser/#/R-BTA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Bos taurus 43474 R-BTA-6788912 https://reactome.org/PathwayBrowser/#/R-BTA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Bos taurus 43474 R-BTA-6792863 https://reactome.org/PathwayBrowser/#/R-BTA-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Bos taurus 43474 R-BTA-6797630 https://reactome.org/PathwayBrowser/#/R-BTA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Bos taurus 43474 R-BTA-6801342 https://reactome.org/PathwayBrowser/#/R-BTA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Bos taurus 43474 R-BTA-6801456 https://reactome.org/PathwayBrowser/#/R-BTA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Bos taurus 43474 R-BTA-6806967 https://reactome.org/PathwayBrowser/#/R-BTA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Bos taurus 43474 R-BTA-6807008 https://reactome.org/PathwayBrowser/#/R-BTA-6807008 PTPRJ dephosphorylates MET IEA Bos taurus 43474 R-BTA-6807027 https://reactome.org/PathwayBrowser/#/R-BTA-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Bos taurus 43474 R-BTA-6809015 https://reactome.org/PathwayBrowser/#/R-BTA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Bos taurus 43474 R-BTA-6809320 https://reactome.org/PathwayBrowser/#/R-BTA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Bos taurus 43474 R-BTA-6809325 https://reactome.org/PathwayBrowser/#/R-BTA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Bos taurus 43474 R-BTA-6809720 https://reactome.org/PathwayBrowser/#/R-BTA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Bos taurus 43474 R-BTA-6809777 https://reactome.org/PathwayBrowser/#/R-BTA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Bos taurus 43474 R-BTA-6809778 https://reactome.org/PathwayBrowser/#/R-BTA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Bos taurus 43474 R-BTA-6810410 https://reactome.org/PathwayBrowser/#/R-BTA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Bos taurus 43474 R-BTA-6811422 https://reactome.org/PathwayBrowser/#/R-BTA-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Bos taurus 43474 R-BTA-6814120 https://reactome.org/PathwayBrowser/#/R-BTA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Bos taurus 43474 R-BTA-68954 https://reactome.org/PathwayBrowser/#/R-BTA-68954 Mcm2-7 is phosphorylated by DDK IEA Bos taurus 43474 R-BTA-69199 https://reactome.org/PathwayBrowser/#/R-BTA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Bos taurus 43474 R-BTA-70262 https://reactome.org/PathwayBrowser/#/R-BTA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Bos taurus 43474 R-BTA-70449 https://reactome.org/PathwayBrowser/#/R-BTA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Bos taurus 43474 R-BTA-70479 https://reactome.org/PathwayBrowser/#/R-BTA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Bos taurus 43474 R-BTA-70482 https://reactome.org/PathwayBrowser/#/R-BTA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Bos taurus 43474 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 43474 R-BTA-70555 https://reactome.org/PathwayBrowser/#/R-BTA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Bos taurus 43474 R-BTA-70560 https://reactome.org/PathwayBrowser/#/R-BTA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Bos taurus 43474 R-BTA-70606 https://reactome.org/PathwayBrowser/#/R-BTA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Bos taurus 43474 R-BTA-70773 https://reactome.org/PathwayBrowser/#/R-BTA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Bos taurus 43474 R-BTA-70997 https://reactome.org/PathwayBrowser/#/R-BTA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Bos taurus 43474 R-BTA-71031 https://reactome.org/PathwayBrowser/#/R-BTA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Bos taurus 43474 R-BTA-71590 https://reactome.org/PathwayBrowser/#/R-BTA-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Bos taurus 43474 R-BTA-71732 https://reactome.org/PathwayBrowser/#/R-BTA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Bos taurus 43474 R-BTA-71775 https://reactome.org/PathwayBrowser/#/R-BTA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Bos taurus 43474 R-BTA-71825 https://reactome.org/PathwayBrowser/#/R-BTA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Bos taurus 43474 R-BTA-72621 https://reactome.org/PathwayBrowser/#/R-BTA-72621 Ribosomal scanning IEA Bos taurus 43474 R-BTA-72671 https://reactome.org/PathwayBrowser/#/R-BTA-72671 eIF5B:GTP is hydrolyzed and released IEA Bos taurus 43474 R-BTA-73573 https://reactome.org/PathwayBrowser/#/R-BTA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Bos taurus 43474 R-BTA-73577 https://reactome.org/PathwayBrowser/#/R-BTA-73577 CAD hexamer transforms L-Gln to CAP IEA Bos taurus 43474 R-BTA-73647 https://reactome.org/PathwayBrowser/#/R-BTA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Bos taurus 43474 R-BTA-73805 https://reactome.org/PathwayBrowser/#/R-BTA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Bos taurus 43474 R-BTA-73810 https://reactome.org/PathwayBrowser/#/R-BTA-73810 FGAM + ATP => AIR + ADP + Pi IEA Bos taurus 43474 R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 43474 R-BTA-73814 https://reactome.org/PathwayBrowser/#/R-BTA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Bos taurus 43474 R-BTA-74242 https://reactome.org/PathwayBrowser/#/R-BTA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Bos taurus 43474 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 43474 R-BTA-74249 https://reactome.org/PathwayBrowser/#/R-BTA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Bos taurus 43474 R-BTA-74372 https://reactome.org/PathwayBrowser/#/R-BTA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Bos taurus 43474 R-BTA-74376 https://reactome.org/PathwayBrowser/#/R-BTA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Bos taurus 43474 R-BTA-74733 https://reactome.org/PathwayBrowser/#/R-BTA-74733 Insulin receptor de-phosphorylation IEA Bos taurus 43474 R-BTA-74948 https://reactome.org/PathwayBrowser/#/R-BTA-74948 PP2A dephosphorylates p-RHO to RHO IEA Bos taurus 43474 R-BTA-75848 https://reactome.org/PathwayBrowser/#/R-BTA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Bos taurus 43474 R-BTA-75851 https://reactome.org/PathwayBrowser/#/R-BTA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 43474 R-BTA-75899 https://reactome.org/PathwayBrowser/#/R-BTA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Bos taurus 43474 R-BTA-75949 https://reactome.org/PathwayBrowser/#/R-BTA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Bos taurus 43474 R-BTA-77078 https://reactome.org/PathwayBrowser/#/R-BTA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Bos taurus 43474 R-BTA-8848053 https://reactome.org/PathwayBrowser/#/R-BTA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Bos taurus 43474 R-BTA-8849082 https://reactome.org/PathwayBrowser/#/R-BTA-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Bos taurus 43474 R-BTA-8849435 https://reactome.org/PathwayBrowser/#/R-BTA-8849435 PTPN1 dephosphorylates PTK6 IEA Bos taurus 43474 R-BTA-8849969 https://reactome.org/PathwayBrowser/#/R-BTA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Bos taurus 43474 R-BTA-8850846 https://reactome.org/PathwayBrowser/#/R-BTA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Bos taurus 43474 R-BTA-8850854 https://reactome.org/PathwayBrowser/#/R-BTA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Bos taurus 43474 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 43474 R-BTA-8851110 https://reactome.org/PathwayBrowser/#/R-BTA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Bos taurus 43474 R-BTA-8851129 https://reactome.org/PathwayBrowser/#/R-BTA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Bos taurus 43474 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 43474 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 43474 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 43474 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 43474 R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 43474 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 43474 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 43474 R-BTA-8852200 https://reactome.org/PathwayBrowser/#/R-BTA-8852200 Inactivation of LCK by PTPN22 IEA Bos taurus 43474 R-BTA-8854173 https://reactome.org/PathwayBrowser/#/R-BTA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Bos taurus 43474 R-BTA-8854255 https://reactome.org/PathwayBrowser/#/R-BTA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Bos taurus 43474 R-BTA-8854329 https://reactome.org/PathwayBrowser/#/R-BTA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Bos taurus 43474 R-BTA-8854604 https://reactome.org/PathwayBrowser/#/R-BTA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Bos taurus 43474 R-BTA-8854612 https://reactome.org/PathwayBrowser/#/R-BTA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Bos taurus 43474 R-BTA-8855381 https://reactome.org/PathwayBrowser/#/R-BTA-8855381 PTPN22 dephosphorylates ZAP70 IEA Bos taurus 43474 R-BTA-8863804 https://reactome.org/PathwayBrowser/#/R-BTA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Bos taurus 43474 R-BTA-8864036 https://reactome.org/PathwayBrowser/#/R-BTA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Bos taurus 43474 R-BTA-8864125 https://reactome.org/PathwayBrowser/#/R-BTA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Bos taurus 43474 R-BTA-8865774 https://reactome.org/PathwayBrowser/#/R-BTA-8865774 TTLLs polyglutamylate tubulin IEA Bos taurus 43474 R-BTA-8866542 https://reactome.org/PathwayBrowser/#/R-BTA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Bos taurus 43474 R-BTA-8867047 https://reactome.org/PathwayBrowser/#/R-BTA-8867047 PTPN3 dephosphorylates EPS15 IEA Bos taurus 43474 R-BTA-8867370 https://reactome.org/PathwayBrowser/#/R-BTA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Bos taurus 43474 R-BTA-8867658 https://reactome.org/PathwayBrowser/#/R-BTA-8867658 PTPN3 dephosphorylates MAPK12 IEA Bos taurus 43474 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 43474 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 43474 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 43474 R-BTA-8876889 https://reactome.org/PathwayBrowser/#/R-BTA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 43474 R-BTA-8878654 https://reactome.org/PathwayBrowser/#/R-BTA-8878654 ACP6 hydrolyses MYS-LPA IEA Bos taurus 43474 R-BTA-8878787 https://reactome.org/PathwayBrowser/#/R-BTA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Bos taurus 43474 R-BTA-8937767 https://reactome.org/PathwayBrowser/#/R-BTA-8937767 PTPN11 dephosphorylates RUNX1 IEA Bos taurus 43474 R-BTA-8940070 https://reactome.org/PathwayBrowser/#/R-BTA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Bos taurus 43474 R-BTA-8940074 https://reactome.org/PathwayBrowser/#/R-BTA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Bos taurus 43474 R-BTA-8951498 https://reactome.org/PathwayBrowser/#/R-BTA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Bos taurus 43474 R-BTA-8952137 https://reactome.org/PathwayBrowser/#/R-BTA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Bos taurus 43474 R-BTA-8953499 https://reactome.org/PathwayBrowser/#/R-BTA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Bos taurus 43474 R-BTA-8955724 https://reactome.org/PathwayBrowser/#/R-BTA-8955724 TTL ligates L-Tyr to the carboxy terminus of alpha-tubulin TAS Bos taurus 43474 R-BTA-8981637 https://reactome.org/PathwayBrowser/#/R-BTA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Bos taurus 43474 R-BTA-8982020 https://reactome.org/PathwayBrowser/#/R-BTA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Bos taurus 43474 R-BTA-8982021 https://reactome.org/PathwayBrowser/#/R-BTA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Bos taurus 43474 R-BTA-8982025 https://reactome.org/PathwayBrowser/#/R-BTA-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Bos taurus 43474 R-BTA-8985594 https://reactome.org/PathwayBrowser/#/R-BTA-8985594 MYO9B inactivates RHOA IEA Bos taurus 43474 R-BTA-9013111 https://reactome.org/PathwayBrowser/#/R-BTA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Bos taurus 43474 R-BTA-9013144 https://reactome.org/PathwayBrowser/#/R-BTA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Bos taurus 43474 R-BTA-9013161 https://reactome.org/PathwayBrowser/#/R-BTA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Bos taurus 43474 R-BTA-9013437 https://reactome.org/PathwayBrowser/#/R-BTA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Bos taurus 43474 R-BTA-9014295 https://reactome.org/PathwayBrowser/#/R-BTA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Bos taurus 43474 R-BTA-9014434 https://reactome.org/PathwayBrowser/#/R-BTA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Bos taurus 43474 R-BTA-9017488 https://reactome.org/PathwayBrowser/#/R-BTA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Bos taurus 43474 R-BTA-9018745 https://reactome.org/PathwayBrowser/#/R-BTA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Bos taurus 43474 R-BTA-9018806 https://reactome.org/PathwayBrowser/#/R-BTA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Bos taurus 43474 R-BTA-9018814 https://reactome.org/PathwayBrowser/#/R-BTA-9018814 RHOT1 hydrolyzes GTP IEA Bos taurus 43474 R-BTA-9018826 https://reactome.org/PathwayBrowser/#/R-BTA-9018826 RHOT2 hydrolyzes GTP IEA Bos taurus 43474 R-BTA-9038161 https://reactome.org/PathwayBrowser/#/R-BTA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Bos taurus 43474 R-BTA-917693 https://reactome.org/PathwayBrowser/#/R-BTA-917693 ESCRT Disassembly IEA Bos taurus 43474 R-BTA-917841 https://reactome.org/PathwayBrowser/#/R-BTA-917841 Acidification of Tf:TfR1 containing endosome IEA Bos taurus 43474 R-BTA-917979 https://reactome.org/PathwayBrowser/#/R-BTA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-936883 https://reactome.org/PathwayBrowser/#/R-BTA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Bos taurus 43474 R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 43474 R-BTA-937311 https://reactome.org/PathwayBrowser/#/R-BTA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Bos taurus 43474 R-BTA-939763 https://reactome.org/PathwayBrowser/#/R-BTA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Bos taurus 43474 R-BTA-947591 https://reactome.org/PathwayBrowser/#/R-BTA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Bos taurus 43474 R-BTA-9624893 https://reactome.org/PathwayBrowser/#/R-BTA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Bos taurus 43474 R-BTA-9635739 https://reactome.org/PathwayBrowser/#/R-BTA-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Bos taurus 43474 R-BTA-9640195 https://reactome.org/PathwayBrowser/#/R-BTA-9640195 RRAGA,B hydrolyzes GTP IEA Bos taurus 43474 R-BTA-9645598 https://reactome.org/PathwayBrowser/#/R-BTA-9645598 RRAGC,D hydrolyzes GTP IEA Bos taurus 43474 R-BTA-965067 https://reactome.org/PathwayBrowser/#/R-BTA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Bos taurus 43474 R-BTA-9658445 https://reactome.org/PathwayBrowser/#/R-BTA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Bos taurus 43474 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 43474 R-BTA-9661417 https://reactome.org/PathwayBrowser/#/R-BTA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-9668419 https://reactome.org/PathwayBrowser/#/R-BTA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Bos taurus 43474 R-BTA-9674816 https://reactome.org/PathwayBrowser/#/R-BTA-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Bos taurus 43474 R-BTA-9684118 https://reactome.org/PathwayBrowser/#/R-BTA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Bos taurus 43474 R-BTA-9686524 https://reactome.org/PathwayBrowser/#/R-BTA-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Bos taurus 43474 R-BTA-9693282 https://reactome.org/PathwayBrowser/#/R-BTA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Bos taurus 43474 R-BTA-9698408 https://reactome.org/PathwayBrowser/#/R-BTA-9698408 PTPRJ dephosphorylates active FLT3 IEA Bos taurus 43474 R-BTA-9700200 https://reactome.org/PathwayBrowser/#/R-BTA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Bos taurus 43474 R-BTA-9701507 https://reactome.org/PathwayBrowser/#/R-BTA-9701507 PTPN6 dephosphorylates JAK3 IEA Bos taurus 43474 R-BTA-9706399 https://reactome.org/PathwayBrowser/#/R-BTA-9706399 RHOBTB3 hydrolyzes ATP IEA Bos taurus 43474 R-BTA-9727198 https://reactome.org/PathwayBrowser/#/R-BTA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Bos taurus 43474 R-BTA-9750546 https://reactome.org/PathwayBrowser/#/R-BTA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-9750617 https://reactome.org/PathwayBrowser/#/R-BTA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-9750656 https://reactome.org/PathwayBrowser/#/R-BTA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Bos taurus 43474 R-BTA-9753278 https://reactome.org/PathwayBrowser/#/R-BTA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 43474 R-BTA-9753283 https://reactome.org/PathwayBrowser/#/R-BTA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 43474 R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 43474 R-BTA-9759206 https://reactome.org/PathwayBrowser/#/R-BTA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Bos taurus 43474 R-BTA-9759454 https://reactome.org/PathwayBrowser/#/R-BTA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Bos taurus 43474 R-BTA-9759461 https://reactome.org/PathwayBrowser/#/R-BTA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Bos taurus 43474 R-BTA-9770141 https://reactome.org/PathwayBrowser/#/R-BTA-9770141 Formation of the Spliceosomal C* complex IEA Bos taurus 43474 R-BTA-9770145 https://reactome.org/PathwayBrowser/#/R-BTA-9770145 Formation of the Spliceosomal Bact complex IEA Bos taurus 43474 R-BTA-977324 https://reactome.org/PathwayBrowser/#/R-BTA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Bos taurus 43474 R-BTA-983144 https://reactome.org/PathwayBrowser/#/R-BTA-983144 Transport of Antigen peptide in to ER IEA Bos taurus 43474 R-BTA-9837419 https://reactome.org/PathwayBrowser/#/R-BTA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Bos taurus 43474 R-BTA-9838004 https://reactome.org/PathwayBrowser/#/R-BTA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Bos taurus 43474 R-BTA-9838081 https://reactome.org/PathwayBrowser/#/R-BTA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Bos taurus 43474 R-BTA-9838289 https://reactome.org/PathwayBrowser/#/R-BTA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Bos taurus 43474 R-BTA-9839059 https://reactome.org/PathwayBrowser/#/R-BTA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Bos taurus 43474 R-BTA-9839105 https://reactome.org/PathwayBrowser/#/R-BTA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Bos taurus 43474 R-BTA-9839113 https://reactome.org/PathwayBrowser/#/R-BTA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Bos taurus 43474 R-BTA-9843721 https://reactome.org/PathwayBrowser/#/R-BTA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Bos taurus 43474 R-BTA-9853385 https://reactome.org/PathwayBrowser/#/R-BTA-9853385 PPP1CC dephosphorylates PLK1 IEA Bos taurus 43474 R-BTA-9861725 https://reactome.org/PathwayBrowser/#/R-BTA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Bos taurus 43474 R-BTA-997309 https://reactome.org/PathwayBrowser/#/R-BTA-997309 Dephosphorylation of STAT1 by SHP2 IEA Bos taurus 43474 R-BTA-997311 https://reactome.org/PathwayBrowser/#/R-BTA-997311 Dephosphorylation of TYK2 by PTP1B IEA Bos taurus 43474 R-BTA-997314 https://reactome.org/PathwayBrowser/#/R-BTA-997314 Dephosphorylation of JAK1 by SHP1 IEA Bos taurus 43474 R-BTA-997326 https://reactome.org/PathwayBrowser/#/R-BTA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Bos taurus 43474 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 43474 R-CEL-111524 https://reactome.org/PathwayBrowser/#/R-CEL-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Caenorhabditis elegans 43474 R-CEL-112033 https://reactome.org/PathwayBrowser/#/R-CEL-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Caenorhabditis elegans 43474 R-CEL-112034 https://reactome.org/PathwayBrowser/#/R-CEL-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Caenorhabditis elegans 43474 R-CEL-112037 https://reactome.org/PathwayBrowser/#/R-CEL-112037 Inactivation of PLC beta IEA Caenorhabditis elegans 43474 R-CEL-1237129 https://reactome.org/PathwayBrowser/#/R-CEL-1237129 Acireductone is created IEA Caenorhabditis elegans 43474 R-CEL-1237160 https://reactome.org/PathwayBrowser/#/R-CEL-1237160 MTA is cleaved and phosphorylated IEA Caenorhabditis elegans 43474 R-CEL-1247935 https://reactome.org/PathwayBrowser/#/R-CEL-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Caenorhabditis elegans 43474 R-CEL-1363274 https://reactome.org/PathwayBrowser/#/R-CEL-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Caenorhabditis elegans 43474 R-CEL-1363276 https://reactome.org/PathwayBrowser/#/R-CEL-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Caenorhabditis elegans 43474 R-CEL-1369065 https://reactome.org/PathwayBrowser/#/R-CEL-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Caenorhabditis elegans 43474 R-CEL-1454916 https://reactome.org/PathwayBrowser/#/R-CEL-1454916 The ABCC family mediates organic anion transport IEA Caenorhabditis elegans 43474 R-CEL-1467466 https://reactome.org/PathwayBrowser/#/R-CEL-1467466 ABCA4 mediates atRAL transport IEA Caenorhabditis elegans 43474 R-CEL-1483203 https://reactome.org/PathwayBrowser/#/R-CEL-1483203 PA is dephosphorylated to DAG by LPIN IEA Caenorhabditis elegans 43474 R-CEL-159101 https://reactome.org/PathwayBrowser/#/R-CEL-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Caenorhabditis elegans 43474 R-CEL-164832 https://reactome.org/PathwayBrowser/#/R-CEL-164832 ATPase synthesizes ATP IEA Caenorhabditis elegans 43474 R-CEL-164840 https://reactome.org/PathwayBrowser/#/R-CEL-164840 ADP and Pi bind to ATPase IEA Caenorhabditis elegans 43474 R-CEL-1675795 https://reactome.org/PathwayBrowser/#/R-CEL-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Caenorhabditis elegans 43474 R-CEL-1675824 https://reactome.org/PathwayBrowser/#/R-CEL-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Caenorhabditis elegans 43474 R-CEL-1675836 https://reactome.org/PathwayBrowser/#/R-CEL-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-1675949 https://reactome.org/PathwayBrowser/#/R-CEL-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-1675988 https://reactome.org/PathwayBrowser/#/R-CEL-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-1675994 https://reactome.org/PathwayBrowser/#/R-CEL-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-1676065 https://reactome.org/PathwayBrowser/#/R-CEL-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Caenorhabditis elegans 43474 R-CEL-1676105 https://reactome.org/PathwayBrowser/#/R-CEL-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Caenorhabditis elegans 43474 R-CEL-1676114 https://reactome.org/PathwayBrowser/#/R-CEL-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Caenorhabditis elegans 43474 R-CEL-1676124 https://reactome.org/PathwayBrowser/#/R-CEL-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Caenorhabditis elegans 43474 R-CEL-1676133 https://reactome.org/PathwayBrowser/#/R-CEL-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Caenorhabditis elegans 43474 R-CEL-1676141 https://reactome.org/PathwayBrowser/#/R-CEL-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Caenorhabditis elegans 43474 R-CEL-1676149 https://reactome.org/PathwayBrowser/#/R-CEL-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-1676162 https://reactome.org/PathwayBrowser/#/R-CEL-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Caenorhabditis elegans 43474 R-CEL-1676164 https://reactome.org/PathwayBrowser/#/R-CEL-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-1676177 https://reactome.org/PathwayBrowser/#/R-CEL-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-1676203 https://reactome.org/PathwayBrowser/#/R-CEL-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-170153 https://reactome.org/PathwayBrowser/#/R-CEL-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Caenorhabditis elegans 43474 R-CEL-170158 https://reactome.org/PathwayBrowser/#/R-CEL-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Caenorhabditis elegans 43474 R-CEL-170161 https://reactome.org/PathwayBrowser/#/R-CEL-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Caenorhabditis elegans 43474 R-CEL-170666 https://reactome.org/PathwayBrowser/#/R-CEL-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Caenorhabditis elegans 43474 R-CEL-170685 https://reactome.org/PathwayBrowser/#/R-CEL-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Caenorhabditis elegans 43474 R-CEL-170686 https://reactome.org/PathwayBrowser/#/R-CEL-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Caenorhabditis elegans 43474 R-CEL-174110 https://reactome.org/PathwayBrowser/#/R-CEL-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Caenorhabditis elegans 43474 R-CEL-174367 https://reactome.org/PathwayBrowser/#/R-CEL-174367 GCL ligates L-Glu to L-Cys IEA Caenorhabditis elegans 43474 R-CEL-174394 https://reactome.org/PathwayBrowser/#/R-CEL-174394 GSS:Mg2+ dimer synthesizes GSH IEA Caenorhabditis elegans 43474 R-CEL-176606 https://reactome.org/PathwayBrowser/#/R-CEL-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Caenorhabditis elegans 43474 R-CEL-1855154 https://reactome.org/PathwayBrowser/#/R-CEL-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-1855165 https://reactome.org/PathwayBrowser/#/R-CEL-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-1855166 https://reactome.org/PathwayBrowser/#/R-CEL-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-1855174 https://reactome.org/PathwayBrowser/#/R-CEL-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-1855180 https://reactome.org/PathwayBrowser/#/R-CEL-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-1855198 https://reactome.org/PathwayBrowser/#/R-CEL-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-1855202 https://reactome.org/PathwayBrowser/#/R-CEL-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-1855205 https://reactome.org/PathwayBrowser/#/R-CEL-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-1855210 https://reactome.org/PathwayBrowser/#/R-CEL-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-1855211 https://reactome.org/PathwayBrowser/#/R-CEL-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-1855213 https://reactome.org/PathwayBrowser/#/R-CEL-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-1855218 https://reactome.org/PathwayBrowser/#/R-CEL-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-1855222 https://reactome.org/PathwayBrowser/#/R-CEL-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-191414 https://reactome.org/PathwayBrowser/#/R-CEL-191414 MVD decarboxylates MVA5PP to IPPP IEA Caenorhabditis elegans 43474 R-CEL-194153 https://reactome.org/PathwayBrowser/#/R-CEL-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-196950 https://reactome.org/PathwayBrowser/#/R-CEL-196950 2xTRAP hydrolyzes FMN to RIB IEA Caenorhabditis elegans 43474 R-CEL-197958 https://reactome.org/PathwayBrowser/#/R-CEL-197958 FPGS-2 transforms THF to THFPG IEA Caenorhabditis elegans 43474 R-CEL-198513 https://reactome.org/PathwayBrowser/#/R-CEL-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Caenorhabditis elegans 43474 R-CEL-199456 https://reactome.org/PathwayBrowser/#/R-CEL-199456 PTEN dephosphorylates PIP3 IEA Caenorhabditis elegans 43474 R-CEL-199959 https://reactome.org/PathwayBrowser/#/R-CEL-199959 ERKs are inactivated by protein phosphatase 2A IEA Caenorhabditis elegans 43474 R-CEL-200555 https://reactome.org/PathwayBrowser/#/R-CEL-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Caenorhabditis elegans 43474 R-CEL-200681 https://reactome.org/PathwayBrowser/#/R-CEL-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Caenorhabditis elegans 43474 R-CEL-200682 https://reactome.org/PathwayBrowser/#/R-CEL-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Caenorhabditis elegans 43474 R-CEL-200711 https://reactome.org/PathwayBrowser/#/R-CEL-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Caenorhabditis elegans 43474 R-CEL-2023971 https://reactome.org/PathwayBrowser/#/R-CEL-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-2023973 https://reactome.org/PathwayBrowser/#/R-CEL-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-203797 https://reactome.org/PathwayBrowser/#/R-CEL-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Caenorhabditis elegans 43474 R-CEL-203973 https://reactome.org/PathwayBrowser/#/R-CEL-203973 Vesicle budding IEA Caenorhabditis elegans 43474 R-CEL-204169 https://reactome.org/PathwayBrowser/#/R-CEL-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Caenorhabditis elegans 43474 R-CEL-2046093 https://reactome.org/PathwayBrowser/#/R-CEL-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Caenorhabditis elegans 43474 R-CEL-209055 https://reactome.org/PathwayBrowser/#/R-CEL-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Caenorhabditis elegans 43474 R-CEL-2395873 https://reactome.org/PathwayBrowser/#/R-CEL-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Caenorhabditis elegans 43474 R-CEL-2395879 https://reactome.org/PathwayBrowser/#/R-CEL-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Caenorhabditis elegans 43474 R-CEL-2395965 https://reactome.org/PathwayBrowser/#/R-CEL-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Caenorhabditis elegans 43474 R-CEL-265783 https://reactome.org/PathwayBrowser/#/R-CEL-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-2682349 https://reactome.org/PathwayBrowser/#/R-CEL-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Caenorhabditis elegans 43474 R-CEL-2872498 https://reactome.org/PathwayBrowser/#/R-CEL-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Caenorhabditis elegans 43474 R-CEL-2995388 https://reactome.org/PathwayBrowser/#/R-CEL-2995388 PP2A dephosphorylates BANF1 IEA Caenorhabditis elegans 43474 R-CEL-3002811 https://reactome.org/PathwayBrowser/#/R-CEL-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Caenorhabditis elegans 43474 R-CEL-3095901 https://reactome.org/PathwayBrowser/#/R-CEL-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-3371422 https://reactome.org/PathwayBrowser/#/R-CEL-3371422 ATP hydrolysis by HSP70 IEA Caenorhabditis elegans 43474 R-CEL-372843 https://reactome.org/PathwayBrowser/#/R-CEL-372843 SLC25A10 mediates exchange of malate and phosphate IEA Caenorhabditis elegans 43474 R-CEL-3781011 https://reactome.org/PathwayBrowser/#/R-CEL-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Caenorhabditis elegans 43474 R-CEL-3781018 https://reactome.org/PathwayBrowser/#/R-CEL-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Caenorhabditis elegans 43474 R-CEL-380949 https://reactome.org/PathwayBrowser/#/R-CEL-380949 AMPK is dephosphorylated IEA Caenorhabditis elegans 43474 R-CEL-380979 https://reactome.org/PathwayBrowser/#/R-CEL-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Caenorhabditis elegans 43474 R-CEL-382560 https://reactome.org/PathwayBrowser/#/R-CEL-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Caenorhabditis elegans 43474 R-CEL-382575 https://reactome.org/PathwayBrowser/#/R-CEL-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Caenorhabditis elegans 43474 R-CEL-383190 https://reactome.org/PathwayBrowser/#/R-CEL-383190 HCO3- transport through ion channel IEA Caenorhabditis elegans 43474 R-CEL-390329 https://reactome.org/PathwayBrowser/#/R-CEL-390329 Dephosphorylation of AKT by PP2A IEA Caenorhabditis elegans 43474 R-CEL-4093339 https://reactome.org/PathwayBrowser/#/R-CEL-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Caenorhabditis elegans 43474 R-CEL-416546 https://reactome.org/PathwayBrowser/#/R-CEL-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Caenorhabditis elegans 43474 R-CEL-416559 https://reactome.org/PathwayBrowser/#/R-CEL-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Caenorhabditis elegans 43474 R-CEL-421831 https://reactome.org/PathwayBrowser/#/R-CEL-421831 trans-Golgi Network Coat Assembly IEA Caenorhabditis elegans 43474 R-CEL-421835 https://reactome.org/PathwayBrowser/#/R-CEL-421835 trans-Golgi Network Vesicle Scission IEA Caenorhabditis elegans 43474 R-CEL-427605 https://reactome.org/PathwayBrowser/#/R-CEL-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 43474 R-CEL-427645 https://reactome.org/PathwayBrowser/#/R-CEL-427645 SLC34A3 cotransports Pi, 2Na+ IEA Caenorhabditis elegans 43474 R-CEL-427656 https://reactome.org/PathwayBrowser/#/R-CEL-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 43474 R-CEL-428609 https://reactome.org/PathwayBrowser/#/R-CEL-428609 Type I Na+-coupled phosphate co-transport IEA Caenorhabditis elegans 43474 R-CEL-428690 https://reactome.org/PathwayBrowser/#/R-CEL-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Caenorhabditis elegans 43474 R-CEL-428696 https://reactome.org/PathwayBrowser/#/R-CEL-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Caenorhabditis elegans 43474 R-CEL-429157 https://reactome.org/PathwayBrowser/#/R-CEL-429157 ABCC4 accumulation of dense granule contents IEA Caenorhabditis elegans 43474 R-CEL-432706 https://reactome.org/PathwayBrowser/#/R-CEL-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Caenorhabditis elegans 43474 R-CEL-432707 https://reactome.org/PathwayBrowser/#/R-CEL-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Caenorhabditis elegans 43474 R-CEL-4419948 https://reactome.org/PathwayBrowser/#/R-CEL-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Caenorhabditis elegans 43474 R-CEL-445699 https://reactome.org/PathwayBrowser/#/R-CEL-445699 ATP Hydrolysis By Myosin IEA Caenorhabditis elegans 43474 R-CEL-449937 https://reactome.org/PathwayBrowser/#/R-CEL-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Caenorhabditis elegans 43474 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 43474 R-CEL-504054 https://reactome.org/PathwayBrowser/#/R-CEL-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Caenorhabditis elegans 43474 R-CEL-508040 https://reactome.org/PathwayBrowser/#/R-CEL-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Caenorhabditis elegans 43474 R-CEL-508308 https://reactome.org/PathwayBrowser/#/R-CEL-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Caenorhabditis elegans 43474 R-CEL-5221130 https://reactome.org/PathwayBrowser/#/R-CEL-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Caenorhabditis elegans 43474 R-CEL-5223317 https://reactome.org/PathwayBrowser/#/R-CEL-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 43474 R-CEL-5251955 https://reactome.org/PathwayBrowser/#/R-CEL-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Caenorhabditis elegans 43474 R-CEL-5251959 https://reactome.org/PathwayBrowser/#/R-CEL-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Caenorhabditis elegans 43474 R-CEL-5251989 https://reactome.org/PathwayBrowser/#/R-CEL-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Caenorhabditis elegans 43474 R-CEL-5419271 https://reactome.org/PathwayBrowser/#/R-CEL-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Caenorhabditis elegans 43474 R-CEL-5419273 https://reactome.org/PathwayBrowser/#/R-CEL-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Caenorhabditis elegans 43474 R-CEL-555065 https://reactome.org/PathwayBrowser/#/R-CEL-555065 Formation of clathrin coated vesicle IEA Caenorhabditis elegans 43474 R-CEL-5672957 https://reactome.org/PathwayBrowser/#/R-CEL-5672957 PP2A dephosphorylates KSR1 IEA Caenorhabditis elegans 43474 R-CEL-5672961 https://reactome.org/PathwayBrowser/#/R-CEL-5672961 PP2A dephosphorylates inactive RAFs IEA Caenorhabditis elegans 43474 R-CEL-5675376 https://reactome.org/PathwayBrowser/#/R-CEL-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Caenorhabditis elegans 43474 R-CEL-5675431 https://reactome.org/PathwayBrowser/#/R-CEL-5675431 PP2A dephosphorylates RAF1 IEA Caenorhabditis elegans 43474 R-CEL-5675433 https://reactome.org/PathwayBrowser/#/R-CEL-5675433 PP5 dephosphorylates RAF1 S338 IEA Caenorhabditis elegans 43474 R-CEL-5678863 https://reactome.org/PathwayBrowser/#/R-CEL-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-5679041 https://reactome.org/PathwayBrowser/#/R-CEL-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-5682285 https://reactome.org/PathwayBrowser/#/R-CEL-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-5683714 https://reactome.org/PathwayBrowser/#/R-CEL-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Caenorhabditis elegans 43474 R-CEL-5683925 https://reactome.org/PathwayBrowser/#/R-CEL-5683925 ULK1 is dephosphorylated IEA Caenorhabditis elegans 43474 R-CEL-5690996 https://reactome.org/PathwayBrowser/#/R-CEL-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Caenorhabditis elegans 43474 R-CEL-5692462 https://reactome.org/PathwayBrowser/#/R-CEL-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Caenorhabditis elegans 43474 R-CEL-5692754 https://reactome.org/PathwayBrowser/#/R-CEL-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Caenorhabditis elegans 43474 R-CEL-5694126 https://reactome.org/PathwayBrowser/#/R-CEL-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Caenorhabditis elegans 43474 R-CEL-5694425 https://reactome.org/PathwayBrowser/#/R-CEL-5694425 NSF ATPase activity dissociates cis-SNARE IEA Caenorhabditis elegans 43474 R-CEL-5694527 https://reactome.org/PathwayBrowser/#/R-CEL-5694527 Loss of SAR1B GTPase IEA Caenorhabditis elegans 43474 R-CEL-5696408 https://reactome.org/PathwayBrowser/#/R-CEL-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Caenorhabditis elegans 43474 R-CEL-5696415 https://reactome.org/PathwayBrowser/#/R-CEL-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Caenorhabditis elegans 43474 R-CEL-5696839 https://reactome.org/PathwayBrowser/#/R-CEL-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Caenorhabditis elegans 43474 R-CEL-6782131 https://reactome.org/PathwayBrowser/#/R-CEL-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Caenorhabditis elegans 43474 R-CEL-6788295 https://reactome.org/PathwayBrowser/#/R-CEL-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Caenorhabditis elegans 43474 R-CEL-6788912 https://reactome.org/PathwayBrowser/#/R-CEL-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Caenorhabditis elegans 43474 R-CEL-6797630 https://reactome.org/PathwayBrowser/#/R-CEL-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Caenorhabditis elegans 43474 R-CEL-6801342 https://reactome.org/PathwayBrowser/#/R-CEL-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Caenorhabditis elegans 43474 R-CEL-6801456 https://reactome.org/PathwayBrowser/#/R-CEL-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Caenorhabditis elegans 43474 R-CEL-6806967 https://reactome.org/PathwayBrowser/#/R-CEL-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Caenorhabditis elegans 43474 R-CEL-6807008 https://reactome.org/PathwayBrowser/#/R-CEL-6807008 PTPRJ dephosphorylates MET IEA Caenorhabditis elegans 43474 R-CEL-6809320 https://reactome.org/PathwayBrowser/#/R-CEL-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-6809325 https://reactome.org/PathwayBrowser/#/R-CEL-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-6809720 https://reactome.org/PathwayBrowser/#/R-CEL-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Caenorhabditis elegans 43474 R-CEL-6809777 https://reactome.org/PathwayBrowser/#/R-CEL-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Caenorhabditis elegans 43474 R-CEL-6809778 https://reactome.org/PathwayBrowser/#/R-CEL-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Caenorhabditis elegans 43474 R-CEL-6810410 https://reactome.org/PathwayBrowser/#/R-CEL-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Caenorhabditis elegans 43474 R-CEL-6811422 https://reactome.org/PathwayBrowser/#/R-CEL-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Caenorhabditis elegans 43474 R-CEL-6811504 https://reactome.org/PathwayBrowser/#/R-CEL-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Caenorhabditis elegans 43474 R-CEL-6814120 https://reactome.org/PathwayBrowser/#/R-CEL-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Caenorhabditis elegans 43474 R-CEL-69199 https://reactome.org/PathwayBrowser/#/R-CEL-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Caenorhabditis elegans 43474 R-CEL-70262 https://reactome.org/PathwayBrowser/#/R-CEL-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Caenorhabditis elegans 43474 R-CEL-70449 https://reactome.org/PathwayBrowser/#/R-CEL-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Caenorhabditis elegans 43474 R-CEL-70479 https://reactome.org/PathwayBrowser/#/R-CEL-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Caenorhabditis elegans 43474 R-CEL-70482 https://reactome.org/PathwayBrowser/#/R-CEL-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Caenorhabditis elegans 43474 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 43474 R-CEL-70606 https://reactome.org/PathwayBrowser/#/R-CEL-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Caenorhabditis elegans 43474 R-CEL-70773 https://reactome.org/PathwayBrowser/#/R-CEL-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Caenorhabditis elegans 43474 R-CEL-70997 https://reactome.org/PathwayBrowser/#/R-CEL-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Caenorhabditis elegans 43474 R-CEL-71031 https://reactome.org/PathwayBrowser/#/R-CEL-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Caenorhabditis elegans 43474 R-CEL-71732 https://reactome.org/PathwayBrowser/#/R-CEL-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Caenorhabditis elegans 43474 R-CEL-71775 https://reactome.org/PathwayBrowser/#/R-CEL-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Caenorhabditis elegans 43474 R-CEL-72621 https://reactome.org/PathwayBrowser/#/R-CEL-72621 Ribosomal scanning IEA Caenorhabditis elegans 43474 R-CEL-72671 https://reactome.org/PathwayBrowser/#/R-CEL-72671 eIF5B:GTP is hydrolyzed and released IEA Caenorhabditis elegans 43474 R-CEL-73573 https://reactome.org/PathwayBrowser/#/R-CEL-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Caenorhabditis elegans 43474 R-CEL-73577 https://reactome.org/PathwayBrowser/#/R-CEL-73577 CAD hexamer transforms L-Gln to CAP IEA Caenorhabditis elegans 43474 R-CEL-73647 https://reactome.org/PathwayBrowser/#/R-CEL-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Caenorhabditis elegans 43474 R-CEL-73805 https://reactome.org/PathwayBrowser/#/R-CEL-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Caenorhabditis elegans 43474 R-CEL-73810 https://reactome.org/PathwayBrowser/#/R-CEL-73810 FGAM + ATP => AIR + ADP + Pi IEA Caenorhabditis elegans 43474 R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 43474 R-CEL-73814 https://reactome.org/PathwayBrowser/#/R-CEL-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Caenorhabditis elegans 43474 R-CEL-74242 https://reactome.org/PathwayBrowser/#/R-CEL-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Caenorhabditis elegans 43474 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 43474 R-CEL-74249 https://reactome.org/PathwayBrowser/#/R-CEL-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Caenorhabditis elegans 43474 R-CEL-74372 https://reactome.org/PathwayBrowser/#/R-CEL-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Caenorhabditis elegans 43474 R-CEL-74376 https://reactome.org/PathwayBrowser/#/R-CEL-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Caenorhabditis elegans 43474 R-CEL-74948 https://reactome.org/PathwayBrowser/#/R-CEL-74948 PP2A dephosphorylates p-RHO to RHO IEA Caenorhabditis elegans 43474 R-CEL-75848 https://reactome.org/PathwayBrowser/#/R-CEL-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Caenorhabditis elegans 43474 R-CEL-75851 https://reactome.org/PathwayBrowser/#/R-CEL-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 43474 R-CEL-75899 https://reactome.org/PathwayBrowser/#/R-CEL-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Caenorhabditis elegans 43474 R-CEL-75949 https://reactome.org/PathwayBrowser/#/R-CEL-75949 RNA Polymerase II Promoter Opening: First Transition IEA Caenorhabditis elegans 43474 R-CEL-77078 https://reactome.org/PathwayBrowser/#/R-CEL-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Caenorhabditis elegans 43474 R-CEL-8849082 https://reactome.org/PathwayBrowser/#/R-CEL-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-8849969 https://reactome.org/PathwayBrowser/#/R-CEL-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Caenorhabditis elegans 43474 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 43474 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 43474 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 43474 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 43474 R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 43474 R-CEL-8854173 https://reactome.org/PathwayBrowser/#/R-CEL-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Caenorhabditis elegans 43474 R-CEL-8854255 https://reactome.org/PathwayBrowser/#/R-CEL-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 43474 R-CEL-8854329 https://reactome.org/PathwayBrowser/#/R-CEL-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 43474 R-CEL-8854612 https://reactome.org/PathwayBrowser/#/R-CEL-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Caenorhabditis elegans 43474 R-CEL-8864125 https://reactome.org/PathwayBrowser/#/R-CEL-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Caenorhabditis elegans 43474 R-CEL-8866542 https://reactome.org/PathwayBrowser/#/R-CEL-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Caenorhabditis elegans 43474 R-CEL-8867047 https://reactome.org/PathwayBrowser/#/R-CEL-8867047 PTPN3 dephosphorylates EPS15 IEA Caenorhabditis elegans 43474 R-CEL-8867658 https://reactome.org/PathwayBrowser/#/R-CEL-8867658 PTPN3 dephosphorylates MAPK12 IEA Caenorhabditis elegans 43474 R-CEL-8868648 https://reactome.org/PathwayBrowser/#/R-CEL-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Caenorhabditis elegans 43474 R-CEL-8868658 https://reactome.org/PathwayBrowser/#/R-CEL-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Caenorhabditis elegans 43474 R-CEL-8868661 https://reactome.org/PathwayBrowser/#/R-CEL-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Caenorhabditis elegans 43474 R-CEL-8876889 https://reactome.org/PathwayBrowser/#/R-CEL-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 43474 R-CEL-8878654 https://reactome.org/PathwayBrowser/#/R-CEL-8878654 ACP6 hydrolyses MYS-LPA IEA Caenorhabditis elegans 43474 R-CEL-8952137 https://reactome.org/PathwayBrowser/#/R-CEL-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Caenorhabditis elegans 43474 R-CEL-8953499 https://reactome.org/PathwayBrowser/#/R-CEL-8953499 IMPAD1 hydrolyses PAP to AMP IEA Caenorhabditis elegans 43474 R-CEL-8959510 https://reactome.org/PathwayBrowser/#/R-CEL-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Caenorhabditis elegans 43474 R-CEL-8981637 https://reactome.org/PathwayBrowser/#/R-CEL-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-8982020 https://reactome.org/PathwayBrowser/#/R-CEL-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Caenorhabditis elegans 43474 R-CEL-8982021 https://reactome.org/PathwayBrowser/#/R-CEL-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Caenorhabditis elegans 43474 R-CEL-8982025 https://reactome.org/PathwayBrowser/#/R-CEL-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Caenorhabditis elegans 43474 R-CEL-8985594 https://reactome.org/PathwayBrowser/#/R-CEL-8985594 MYO9B inactivates RHOA IEA Caenorhabditis elegans 43474 R-CEL-9013022 https://reactome.org/PathwayBrowser/#/R-CEL-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-9013144 https://reactome.org/PathwayBrowser/#/R-CEL-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-9013161 https://reactome.org/PathwayBrowser/#/R-CEL-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-9013437 https://reactome.org/PathwayBrowser/#/R-CEL-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-9014295 https://reactome.org/PathwayBrowser/#/R-CEL-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-9014434 https://reactome.org/PathwayBrowser/#/R-CEL-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-9017488 https://reactome.org/PathwayBrowser/#/R-CEL-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-9018745 https://reactome.org/PathwayBrowser/#/R-CEL-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-9018806 https://reactome.org/PathwayBrowser/#/R-CEL-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-9018814 https://reactome.org/PathwayBrowser/#/R-CEL-9018814 RHOT1 hydrolyzes GTP IEA Caenorhabditis elegans 43474 R-CEL-9018826 https://reactome.org/PathwayBrowser/#/R-CEL-9018826 RHOT2 hydrolyzes GTP IEA Caenorhabditis elegans 43474 R-CEL-917841 https://reactome.org/PathwayBrowser/#/R-CEL-917841 Acidification of Tf:TfR1 containing endosome IEA Caenorhabditis elegans 43474 R-CEL-917979 https://reactome.org/PathwayBrowser/#/R-CEL-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-936883 https://reactome.org/PathwayBrowser/#/R-CEL-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Caenorhabditis elegans 43474 R-CEL-936895 https://reactome.org/PathwayBrowser/#/R-CEL-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Caenorhabditis elegans 43474 R-CEL-939763 https://reactome.org/PathwayBrowser/#/R-CEL-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-947591 https://reactome.org/PathwayBrowser/#/R-CEL-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Caenorhabditis elegans 43474 R-CEL-9624893 https://reactome.org/PathwayBrowser/#/R-CEL-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Caenorhabditis elegans 43474 R-CEL-9640195 https://reactome.org/PathwayBrowser/#/R-CEL-9640195 RRAGA,B hydrolyzes GTP IEA Caenorhabditis elegans 43474 R-CEL-9645598 https://reactome.org/PathwayBrowser/#/R-CEL-9645598 RRAGC,D hydrolyzes GTP IEA Caenorhabditis elegans 43474 R-CEL-9658445 https://reactome.org/PathwayBrowser/#/R-CEL-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Caenorhabditis elegans 43474 R-CEL-9661417 https://reactome.org/PathwayBrowser/#/R-CEL-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-9684118 https://reactome.org/PathwayBrowser/#/R-CEL-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Caenorhabditis elegans 43474 R-CEL-9693282 https://reactome.org/PathwayBrowser/#/R-CEL-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Caenorhabditis elegans 43474 R-CEL-9706399 https://reactome.org/PathwayBrowser/#/R-CEL-9706399 RHOBTB3 hydrolyzes ATP IEA Caenorhabditis elegans 43474 R-CEL-9750546 https://reactome.org/PathwayBrowser/#/R-CEL-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-9750617 https://reactome.org/PathwayBrowser/#/R-CEL-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-9750656 https://reactome.org/PathwayBrowser/#/R-CEL-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Caenorhabditis elegans 43474 R-CEL-9753278 https://reactome.org/PathwayBrowser/#/R-CEL-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 43474 R-CEL-9753283 https://reactome.org/PathwayBrowser/#/R-CEL-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 43474 R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-9770141 https://reactome.org/PathwayBrowser/#/R-CEL-9770141 Formation of the Spliceosomal C* complex IEA Caenorhabditis elegans 43474 R-CEL-977324 https://reactome.org/PathwayBrowser/#/R-CEL-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Caenorhabditis elegans 43474 R-CEL-983144 https://reactome.org/PathwayBrowser/#/R-CEL-983144 Transport of Antigen peptide in to ER IEA Caenorhabditis elegans 43474 R-CEL-9837419 https://reactome.org/PathwayBrowser/#/R-CEL-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Caenorhabditis elegans 43474 R-CEL-9838004 https://reactome.org/PathwayBrowser/#/R-CEL-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Caenorhabditis elegans 43474 R-CEL-9838081 https://reactome.org/PathwayBrowser/#/R-CEL-9838081 LONP1 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 43474 R-CEL-9838289 https://reactome.org/PathwayBrowser/#/R-CEL-9838289 CLPXP degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 43474 R-CEL-9839059 https://reactome.org/PathwayBrowser/#/R-CEL-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Caenorhabditis elegans 43474 R-CEL-9839105 https://reactome.org/PathwayBrowser/#/R-CEL-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 43474 R-CEL-9839113 https://reactome.org/PathwayBrowser/#/R-CEL-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Caenorhabditis elegans 43474 R-CEL-9843721 https://reactome.org/PathwayBrowser/#/R-CEL-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Caenorhabditis elegans 43474 R-CEL-9853385 https://reactome.org/PathwayBrowser/#/R-CEL-9853385 PPP1CC dephosphorylates PLK1 IEA Caenorhabditis elegans 43474 R-CEL-9861725 https://reactome.org/PathwayBrowser/#/R-CEL-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Caenorhabditis elegans 43474 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 43474 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 43474 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 43474 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 43474 R-CFA-109415 https://reactome.org/PathwayBrowser/#/R-CFA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Canis familiaris 43474 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 43474 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 43474 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 43474 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 43474 R-CFA-111215 https://reactome.org/PathwayBrowser/#/R-CFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Canis familiaris 43474 R-CFA-111524 https://reactome.org/PathwayBrowser/#/R-CFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Canis familiaris 43474 R-CFA-112033 https://reactome.org/PathwayBrowser/#/R-CFA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Canis familiaris 43474 R-CFA-112034 https://reactome.org/PathwayBrowser/#/R-CFA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Canis familiaris 43474 R-CFA-112037 https://reactome.org/PathwayBrowser/#/R-CFA-112037 Inactivation of PLC beta IEA Canis familiaris 43474 R-CFA-113503 https://reactome.org/PathwayBrowser/#/R-CFA-113503 PP2A mediated localization of RB1 protein in chromatin IEA Canis familiaris 43474 R-CFA-1169192 https://reactome.org/PathwayBrowser/#/R-CFA-1169192 PTP1B dephosphorylates GHR IEA Canis familiaris 43474 R-CFA-1237129 https://reactome.org/PathwayBrowser/#/R-CFA-1237129 Acireductone is created IEA Canis familiaris 43474 R-CFA-1237160 https://reactome.org/PathwayBrowser/#/R-CFA-1237160 MTA is cleaved and phosphorylated IEA Canis familiaris 43474 R-CFA-1247935 https://reactome.org/PathwayBrowser/#/R-CFA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Canis familiaris 43474 R-CFA-1295632 https://reactome.org/PathwayBrowser/#/R-CFA-1295632 PPA2A dephosphorylates SPRY2 IEA Canis familiaris 43474 R-CFA-1363274 https://reactome.org/PathwayBrowser/#/R-CFA-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Canis familiaris 43474 R-CFA-1363276 https://reactome.org/PathwayBrowser/#/R-CFA-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Canis familiaris 43474 R-CFA-1369065 https://reactome.org/PathwayBrowser/#/R-CFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Canis familiaris 43474 R-CFA-139906 https://reactome.org/PathwayBrowser/#/R-CFA-139906 Activation of BAD by calcineurin IEA Canis familiaris 43474 R-CFA-1454916 https://reactome.org/PathwayBrowser/#/R-CFA-1454916 The ABCC family mediates organic anion transport IEA Canis familiaris 43474 R-CFA-1454928 https://reactome.org/PathwayBrowser/#/R-CFA-1454928 ABCG4 may mediate cholesterol efflux IEA Canis familiaris 43474 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-1467466 https://reactome.org/PathwayBrowser/#/R-CFA-1467466 ABCA4 mediates atRAL transport IEA Canis familiaris 43474 R-CFA-1483096 https://reactome.org/PathwayBrowser/#/R-CFA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Canis familiaris 43474 R-CFA-1483159 https://reactome.org/PathwayBrowser/#/R-CFA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Canis familiaris 43474 R-CFA-1483203 https://reactome.org/PathwayBrowser/#/R-CFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Canis familiaris 43474 R-CFA-1638821 https://reactome.org/PathwayBrowser/#/R-CFA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Canis familiaris 43474 R-CFA-164832 https://reactome.org/PathwayBrowser/#/R-CFA-164832 ATPase synthesizes ATP IEA Canis familiaris 43474 R-CFA-164840 https://reactome.org/PathwayBrowser/#/R-CFA-164840 ADP and Pi bind to ATPase IEA Canis familiaris 43474 R-CFA-1675795 https://reactome.org/PathwayBrowser/#/R-CFA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Canis familiaris 43474 R-CFA-1675824 https://reactome.org/PathwayBrowser/#/R-CFA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Canis familiaris 43474 R-CFA-1675836 https://reactome.org/PathwayBrowser/#/R-CFA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Canis familiaris 43474 R-CFA-1675949 https://reactome.org/PathwayBrowser/#/R-CFA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Canis familiaris 43474 R-CFA-1675988 https://reactome.org/PathwayBrowser/#/R-CFA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Canis familiaris 43474 R-CFA-1675994 https://reactome.org/PathwayBrowser/#/R-CFA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Canis familiaris 43474 R-CFA-1676005 https://reactome.org/PathwayBrowser/#/R-CFA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Canis familiaris 43474 R-CFA-1676020 https://reactome.org/PathwayBrowser/#/R-CFA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Canis familiaris 43474 R-CFA-1676065 https://reactome.org/PathwayBrowser/#/R-CFA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Canis familiaris 43474 R-CFA-1676105 https://reactome.org/PathwayBrowser/#/R-CFA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Canis familiaris 43474 R-CFA-1676114 https://reactome.org/PathwayBrowser/#/R-CFA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Canis familiaris 43474 R-CFA-1676124 https://reactome.org/PathwayBrowser/#/R-CFA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Canis familiaris 43474 R-CFA-1676133 https://reactome.org/PathwayBrowser/#/R-CFA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Canis familiaris 43474 R-CFA-1676141 https://reactome.org/PathwayBrowser/#/R-CFA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Canis familiaris 43474 R-CFA-1676149 https://reactome.org/PathwayBrowser/#/R-CFA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Canis familiaris 43474 R-CFA-1676162 https://reactome.org/PathwayBrowser/#/R-CFA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Canis familiaris 43474 R-CFA-1676164 https://reactome.org/PathwayBrowser/#/R-CFA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Canis familiaris 43474 R-CFA-1676174 https://reactome.org/PathwayBrowser/#/R-CFA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Canis familiaris 43474 R-CFA-1676177 https://reactome.org/PathwayBrowser/#/R-CFA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Canis familiaris 43474 R-CFA-1676203 https://reactome.org/PathwayBrowser/#/R-CFA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Canis familiaris 43474 R-CFA-1676204 https://reactome.org/PathwayBrowser/#/R-CFA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Canis familiaris 43474 R-CFA-170153 https://reactome.org/PathwayBrowser/#/R-CFA-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Canis familiaris 43474 R-CFA-170158 https://reactome.org/PathwayBrowser/#/R-CFA-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Canis familiaris 43474 R-CFA-170161 https://reactome.org/PathwayBrowser/#/R-CFA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Canis familiaris 43474 R-CFA-170666 https://reactome.org/PathwayBrowser/#/R-CFA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Canis familiaris 43474 R-CFA-170685 https://reactome.org/PathwayBrowser/#/R-CFA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Canis familiaris 43474 R-CFA-170686 https://reactome.org/PathwayBrowser/#/R-CFA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Canis familiaris 43474 R-CFA-174110 https://reactome.org/PathwayBrowser/#/R-CFA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Canis familiaris 43474 R-CFA-174367 https://reactome.org/PathwayBrowser/#/R-CFA-174367 GCL ligates L-Glu to L-Cys IEA Canis familiaris 43474 R-CFA-174391 https://reactome.org/PathwayBrowser/#/R-CFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Canis familiaris 43474 R-CFA-174394 https://reactome.org/PathwayBrowser/#/R-CFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Canis familiaris 43474 R-CFA-174438 https://reactome.org/PathwayBrowser/#/R-CFA-174438 Formation of the Flap Intermediate on the C-strand IEA Canis familiaris 43474 R-CFA-174439 https://reactome.org/PathwayBrowser/#/R-CFA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Canis familiaris 43474 R-CFA-176606 https://reactome.org/PathwayBrowser/#/R-CFA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Canis familiaris 43474 R-CFA-177923 https://reactome.org/PathwayBrowser/#/R-CFA-177923 Sustained activation of SRC kinase by SHP2 IEA Canis familiaris 43474 R-CFA-177924 https://reactome.org/PathwayBrowser/#/R-CFA-177924 Dephosphorylation of Gab1 by SHP2 IEA Canis familiaris 43474 R-CFA-177926 https://reactome.org/PathwayBrowser/#/R-CFA-177926 Dephosphorylation of PAG by SHP2 IEA Canis familiaris 43474 R-CFA-177935 https://reactome.org/PathwayBrowser/#/R-CFA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Canis familiaris 43474 R-CFA-1855154 https://reactome.org/PathwayBrowser/#/R-CFA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 43474 R-CFA-1855159 https://reactome.org/PathwayBrowser/#/R-CFA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Canis familiaris 43474 R-CFA-1855163 https://reactome.org/PathwayBrowser/#/R-CFA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Canis familiaris 43474 R-CFA-1855165 https://reactome.org/PathwayBrowser/#/R-CFA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 43474 R-CFA-1855166 https://reactome.org/PathwayBrowser/#/R-CFA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Canis familiaris 43474 R-CFA-1855171 https://reactome.org/PathwayBrowser/#/R-CFA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Canis familiaris 43474 R-CFA-1855174 https://reactome.org/PathwayBrowser/#/R-CFA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Canis familiaris 43474 R-CFA-1855180 https://reactome.org/PathwayBrowser/#/R-CFA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Canis familiaris 43474 R-CFA-1855198 https://reactome.org/PathwayBrowser/#/R-CFA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 43474 R-CFA-1855200 https://reactome.org/PathwayBrowser/#/R-CFA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Canis familiaris 43474 R-CFA-1855202 https://reactome.org/PathwayBrowser/#/R-CFA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Canis familiaris 43474 R-CFA-1855205 https://reactome.org/PathwayBrowser/#/R-CFA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Canis familiaris 43474 R-CFA-1855208 https://reactome.org/PathwayBrowser/#/R-CFA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Canis familiaris 43474 R-CFA-1855210 https://reactome.org/PathwayBrowser/#/R-CFA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 43474 R-CFA-1855211 https://reactome.org/PathwayBrowser/#/R-CFA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 43474 R-CFA-1855213 https://reactome.org/PathwayBrowser/#/R-CFA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Canis familiaris 43474 R-CFA-1855218 https://reactome.org/PathwayBrowser/#/R-CFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Canis familiaris 43474 R-CFA-1855219 https://reactome.org/PathwayBrowser/#/R-CFA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 43474 R-CFA-1855222 https://reactome.org/PathwayBrowser/#/R-CFA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Canis familiaris 43474 R-CFA-1855225 https://reactome.org/PathwayBrowser/#/R-CFA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Canis familiaris 43474 R-CFA-1855232 https://reactome.org/PathwayBrowser/#/R-CFA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Canis familiaris 43474 R-CFA-1861595 https://reactome.org/PathwayBrowser/#/R-CFA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Canis familiaris 43474 R-CFA-191414 https://reactome.org/PathwayBrowser/#/R-CFA-191414 MVD decarboxylates MVA5PP to IPPP IEA Canis familiaris 43474 R-CFA-193362 https://reactome.org/PathwayBrowser/#/R-CFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-194153 https://reactome.org/PathwayBrowser/#/R-CFA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-196950 https://reactome.org/PathwayBrowser/#/R-CFA-196950 2xTRAP hydrolyzes FMN to RIB IEA Canis familiaris 43474 R-CFA-197958 https://reactome.org/PathwayBrowser/#/R-CFA-197958 FPGS-2 transforms THF to THFPG IEA Canis familiaris 43474 R-CFA-198513 https://reactome.org/PathwayBrowser/#/R-CFA-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Canis familiaris 43474 R-CFA-199456 https://reactome.org/PathwayBrowser/#/R-CFA-199456 PTEN dephosphorylates PIP3 IEA Canis familiaris 43474 R-CFA-199959 https://reactome.org/PathwayBrowser/#/R-CFA-199959 ERKs are inactivated by protein phosphatase 2A IEA Canis familiaris 43474 R-CFA-200555 https://reactome.org/PathwayBrowser/#/R-CFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Canis familiaris 43474 R-CFA-200681 https://reactome.org/PathwayBrowser/#/R-CFA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Canis familiaris 43474 R-CFA-200682 https://reactome.org/PathwayBrowser/#/R-CFA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Canis familiaris 43474 R-CFA-200711 https://reactome.org/PathwayBrowser/#/R-CFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Canis familiaris 43474 R-CFA-201790 https://reactome.org/PathwayBrowser/#/R-CFA-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Canis familiaris 43474 R-CFA-202214 https://reactome.org/PathwayBrowser/#/R-CFA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Canis familiaris 43474 R-CFA-202237 https://reactome.org/PathwayBrowser/#/R-CFA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Canis familiaris 43474 R-CFA-2023971 https://reactome.org/PathwayBrowser/#/R-CFA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 43474 R-CFA-2023973 https://reactome.org/PathwayBrowser/#/R-CFA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 43474 R-CFA-2029468 https://reactome.org/PathwayBrowser/#/R-CFA-2029468 Conversion of PA into DAG by PAP-1 IEA Canis familiaris 43474 R-CFA-2029476 https://reactome.org/PathwayBrowser/#/R-CFA-2029476 Role of myosins in phagosome formation IEA Canis familiaris 43474 R-CFA-203797 https://reactome.org/PathwayBrowser/#/R-CFA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Canis familiaris 43474 R-CFA-203973 https://reactome.org/PathwayBrowser/#/R-CFA-203973 Vesicle budding IEA Canis familiaris 43474 R-CFA-204169 https://reactome.org/PathwayBrowser/#/R-CFA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Canis familiaris 43474 R-CFA-2046093 https://reactome.org/PathwayBrowser/#/R-CFA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Canis familiaris 43474 R-CFA-209055 https://reactome.org/PathwayBrowser/#/R-CFA-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Canis familiaris 43474 R-CFA-2130641 https://reactome.org/PathwayBrowser/#/R-CFA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Canis familiaris 43474 R-CFA-2130725 https://reactome.org/PathwayBrowser/#/R-CFA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Canis familiaris 43474 R-CFA-216723 https://reactome.org/PathwayBrowser/#/R-CFA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Canis familiaris 43474 R-CFA-216757 https://reactome.org/PathwayBrowser/#/R-CFA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Canis familiaris 43474 R-CFA-2187401 https://reactome.org/PathwayBrowser/#/R-CFA-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Canis familiaris 43474 R-CFA-2395873 https://reactome.org/PathwayBrowser/#/R-CFA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Canis familiaris 43474 R-CFA-2395876 https://reactome.org/PathwayBrowser/#/R-CFA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 43474 R-CFA-2395879 https://reactome.org/PathwayBrowser/#/R-CFA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 43474 R-CFA-2395965 https://reactome.org/PathwayBrowser/#/R-CFA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Canis familiaris 43474 R-CFA-2408551 https://reactome.org/PathwayBrowser/#/R-CFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Canis familiaris 43474 R-CFA-2509793 https://reactome.org/PathwayBrowser/#/R-CFA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Canis familiaris 43474 R-CFA-2509816 https://reactome.org/PathwayBrowser/#/R-CFA-2509816 NUDT16 hydrolyses IDP to IMP IEA Canis familiaris 43474 R-CFA-2529015 https://reactome.org/PathwayBrowser/#/R-CFA-2529015 Dephosphorylation of CK2-modified condensin I IEA Canis familiaris 43474 R-CFA-2584246 https://reactome.org/PathwayBrowser/#/R-CFA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Canis familiaris 43474 R-CFA-265783 https://reactome.org/PathwayBrowser/#/R-CFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-266082 https://reactome.org/PathwayBrowser/#/R-CFA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Canis familiaris 43474 R-CFA-2682349 https://reactome.org/PathwayBrowser/#/R-CFA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Canis familiaris 43474 R-CFA-2730849 https://reactome.org/PathwayBrowser/#/R-CFA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Canis familiaris 43474 R-CFA-2872498 https://reactome.org/PathwayBrowser/#/R-CFA-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Canis familiaris 43474 R-CFA-2995388 https://reactome.org/PathwayBrowser/#/R-CFA-2995388 PP2A dephosphorylates BANF1 IEA Canis familiaris 43474 R-CFA-3002811 https://reactome.org/PathwayBrowser/#/R-CFA-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Canis familiaris 43474 R-CFA-3095901 https://reactome.org/PathwayBrowser/#/R-CFA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Canis familiaris 43474 R-CFA-3257122 https://reactome.org/PathwayBrowser/#/R-CFA-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Canis familiaris 43474 R-CFA-3262512 https://reactome.org/PathwayBrowser/#/R-CFA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Canis familiaris 43474 R-CFA-3266566 https://reactome.org/PathwayBrowser/#/R-CFA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Canis familiaris 43474 R-CFA-3371422 https://reactome.org/PathwayBrowser/#/R-CFA-3371422 ATP hydrolysis by HSP70 IEA Canis familiaris 43474 R-CFA-372843 https://reactome.org/PathwayBrowser/#/R-CFA-372843 SLC25A10 mediates exchange of malate and phosphate IEA Canis familiaris 43474 R-CFA-377643 https://reactome.org/PathwayBrowser/#/R-CFA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Canis familiaris 43474 R-CFA-3781011 https://reactome.org/PathwayBrowser/#/R-CFA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Canis familiaris 43474 R-CFA-3781018 https://reactome.org/PathwayBrowser/#/R-CFA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Canis familiaris 43474 R-CFA-380949 https://reactome.org/PathwayBrowser/#/R-CFA-380949 AMPK is dephosphorylated IEA Canis familiaris 43474 R-CFA-380979 https://reactome.org/PathwayBrowser/#/R-CFA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Canis familiaris 43474 R-CFA-382553 https://reactome.org/PathwayBrowser/#/R-CFA-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Canis familiaris 43474 R-CFA-382560 https://reactome.org/PathwayBrowser/#/R-CFA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Canis familiaris 43474 R-CFA-382575 https://reactome.org/PathwayBrowser/#/R-CFA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Canis familiaris 43474 R-CFA-383190 https://reactome.org/PathwayBrowser/#/R-CFA-383190 HCO3- transport through ion channel IEA Canis familiaris 43474 R-CFA-390593 https://reactome.org/PathwayBrowser/#/R-CFA-390593 ATP Hydrolysis By Myosin IEA Canis familiaris 43474 R-CFA-4084976 https://reactome.org/PathwayBrowser/#/R-CFA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Canis familiaris 43474 R-CFA-4084989 https://reactome.org/PathwayBrowser/#/R-CFA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Canis familiaris 43474 R-CFA-4088141 https://reactome.org/PathwayBrowser/#/R-CFA-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Canis familiaris 43474 R-CFA-4093339 https://reactome.org/PathwayBrowser/#/R-CFA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Canis familiaris 43474 R-CFA-416320 https://reactome.org/PathwayBrowser/#/R-CFA-416320 Trafficking of GluR1-containing AMPA receptors IEA Canis familiaris 43474 R-CFA-416546 https://reactome.org/PathwayBrowser/#/R-CFA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Canis familiaris 43474 R-CFA-416559 https://reactome.org/PathwayBrowser/#/R-CFA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Canis familiaris 43474 R-CFA-416639 https://reactome.org/PathwayBrowser/#/R-CFA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Canis familiaris 43474 R-CFA-416985 https://reactome.org/PathwayBrowser/#/R-CFA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Canis familiaris 43474 R-CFA-421007 https://reactome.org/PathwayBrowser/#/R-CFA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Canis familiaris 43474 R-CFA-421831 https://reactome.org/PathwayBrowser/#/R-CFA-421831 trans-Golgi Network Coat Assembly IEA Canis familiaris 43474 R-CFA-421835 https://reactome.org/PathwayBrowser/#/R-CFA-421835 trans-Golgi Network Vesicle Scission IEA Canis familiaris 43474 R-CFA-421836 https://reactome.org/PathwayBrowser/#/R-CFA-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Canis familiaris 43474 R-CFA-427605 https://reactome.org/PathwayBrowser/#/R-CFA-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Canis familiaris 43474 R-CFA-427645 https://reactome.org/PathwayBrowser/#/R-CFA-427645 SLC34A3 cotransports Pi, 2Na+ IEA Canis familiaris 43474 R-CFA-427656 https://reactome.org/PathwayBrowser/#/R-CFA-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Canis familiaris 43474 R-CFA-428609 https://reactome.org/PathwayBrowser/#/R-CFA-428609 Type I Na+-coupled phosphate co-transport IEA Canis familiaris 43474 R-CFA-428664 https://reactome.org/PathwayBrowser/#/R-CFA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Canis familiaris 43474 R-CFA-428690 https://reactome.org/PathwayBrowser/#/R-CFA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Canis familiaris 43474 R-CFA-428696 https://reactome.org/PathwayBrowser/#/R-CFA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Canis familiaris 43474 R-CFA-429157 https://reactome.org/PathwayBrowser/#/R-CFA-429157 ABCC4 accumulation of dense granule contents IEA Canis familiaris 43474 R-CFA-432688 https://reactome.org/PathwayBrowser/#/R-CFA-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating IEA Canis familiaris 43474 R-CFA-432706 https://reactome.org/PathwayBrowser/#/R-CFA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Canis familiaris 43474 R-CFA-432707 https://reactome.org/PathwayBrowser/#/R-CFA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Canis familiaris 43474 R-CFA-4419948 https://reactome.org/PathwayBrowser/#/R-CFA-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Canis familiaris 43474 R-CFA-445699 https://reactome.org/PathwayBrowser/#/R-CFA-445699 ATP Hydrolysis By Myosin IEA Canis familiaris 43474 R-CFA-446200 https://reactome.org/PathwayBrowser/#/R-CFA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Canis familiaris 43474 R-CFA-449937 https://reactome.org/PathwayBrowser/#/R-CFA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Canis familiaris 43474 R-CFA-453339 https://reactome.org/PathwayBrowser/#/R-CFA-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Canis familiaris 43474 R-CFA-4551451 https://reactome.org/PathwayBrowser/#/R-CFA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Canis familiaris 43474 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 43474 R-CFA-504054 https://reactome.org/PathwayBrowser/#/R-CFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Canis familiaris 43474 R-CFA-508040 https://reactome.org/PathwayBrowser/#/R-CFA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Canis familiaris 43474 R-CFA-508308 https://reactome.org/PathwayBrowser/#/R-CFA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Canis familiaris 43474 R-CFA-5221130 https://reactome.org/PathwayBrowser/#/R-CFA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Canis familiaris 43474 R-CFA-5223313 https://reactome.org/PathwayBrowser/#/R-CFA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Canis familiaris 43474 R-CFA-5223317 https://reactome.org/PathwayBrowser/#/R-CFA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Canis familiaris 43474 R-CFA-5251955 https://reactome.org/PathwayBrowser/#/R-CFA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Canis familiaris 43474 R-CFA-5251959 https://reactome.org/PathwayBrowser/#/R-CFA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Canis familiaris 43474 R-CFA-5251989 https://reactome.org/PathwayBrowser/#/R-CFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Canis familiaris 43474 R-CFA-5419271 https://reactome.org/PathwayBrowser/#/R-CFA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Canis familiaris 43474 R-CFA-5419273 https://reactome.org/PathwayBrowser/#/R-CFA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Canis familiaris 43474 R-CFA-555065 https://reactome.org/PathwayBrowser/#/R-CFA-555065 Formation of clathrin coated vesicle IEA Canis familiaris 43474 R-CFA-5603114 https://reactome.org/PathwayBrowser/#/R-CFA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Canis familiaris 43474 R-CFA-5623513 https://reactome.org/PathwayBrowser/#/R-CFA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Canis familiaris 43474 R-CFA-5628905 https://reactome.org/PathwayBrowser/#/R-CFA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Canis familiaris 43474 R-CFA-5649705 https://reactome.org/PathwayBrowser/#/R-CFA-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Canis familiaris 43474 R-CFA-5665809 https://reactome.org/PathwayBrowser/#/R-CFA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Canis familiaris 43474 R-CFA-5675373 https://reactome.org/PathwayBrowser/#/R-CFA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Canis familiaris 43474 R-CFA-5675376 https://reactome.org/PathwayBrowser/#/R-CFA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Canis familiaris 43474 R-CFA-5675431 https://reactome.org/PathwayBrowser/#/R-CFA-5675431 PP2A dephosphorylates RAF1 IEA Canis familiaris 43474 R-CFA-5675433 https://reactome.org/PathwayBrowser/#/R-CFA-5675433 PP5 dephosphorylates RAF1 S338 IEA Canis familiaris 43474 R-CFA-5678706 https://reactome.org/PathwayBrowser/#/R-CFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Canis familiaris 43474 R-CFA-5678863 https://reactome.org/PathwayBrowser/#/R-CFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-5679041 https://reactome.org/PathwayBrowser/#/R-CFA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-5682285 https://reactome.org/PathwayBrowser/#/R-CFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-5683405 https://reactome.org/PathwayBrowser/#/R-CFA-5683405 PPP5C dephosphorylates TP53BP1 IEA Canis familiaris 43474 R-CFA-5683714 https://reactome.org/PathwayBrowser/#/R-CFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Canis familiaris 43474 R-CFA-5683925 https://reactome.org/PathwayBrowser/#/R-CFA-5683925 ULK1 is dephosphorylated IEA Canis familiaris 43474 R-CFA-5683967 https://reactome.org/PathwayBrowser/#/R-CFA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Canis familiaris 43474 R-CFA-5687758 https://reactome.org/PathwayBrowser/#/R-CFA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Canis familiaris 43474 R-CFA-5690996 https://reactome.org/PathwayBrowser/#/R-CFA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Canis familiaris 43474 R-CFA-5692462 https://reactome.org/PathwayBrowser/#/R-CFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Canis familiaris 43474 R-CFA-5692480 https://reactome.org/PathwayBrowser/#/R-CFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Canis familiaris 43474 R-CFA-5692754 https://reactome.org/PathwayBrowser/#/R-CFA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Canis familiaris 43474 R-CFA-5693153 https://reactome.org/PathwayBrowser/#/R-CFA-5693153 PPM1K dephosphorylates p-BCKDH IEA Canis familiaris 43474 R-CFA-5694126 https://reactome.org/PathwayBrowser/#/R-CFA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Canis familiaris 43474 R-CFA-5694421 https://reactome.org/PathwayBrowser/#/R-CFA-5694421 PP6 dephosphorylates SEC24 IEA Canis familiaris 43474 R-CFA-5694425 https://reactome.org/PathwayBrowser/#/R-CFA-5694425 NSF ATPase activity dissociates cis-SNARE IEA Canis familiaris 43474 R-CFA-5694527 https://reactome.org/PathwayBrowser/#/R-CFA-5694527 Loss of SAR1B GTPase IEA Canis familiaris 43474 R-CFA-5696408 https://reactome.org/PathwayBrowser/#/R-CFA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Canis familiaris 43474 R-CFA-5696415 https://reactome.org/PathwayBrowser/#/R-CFA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Canis familiaris 43474 R-CFA-5696839 https://reactome.org/PathwayBrowser/#/R-CFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Canis familiaris 43474 R-CFA-6782131 https://reactome.org/PathwayBrowser/#/R-CFA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Canis familiaris 43474 R-CFA-6786245 https://reactome.org/PathwayBrowser/#/R-CFA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Canis familiaris 43474 R-CFA-6788295 https://reactome.org/PathwayBrowser/#/R-CFA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Canis familiaris 43474 R-CFA-6788912 https://reactome.org/PathwayBrowser/#/R-CFA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Canis familiaris 43474 R-CFA-6792863 https://reactome.org/PathwayBrowser/#/R-CFA-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Canis familiaris 43474 R-CFA-6797630 https://reactome.org/PathwayBrowser/#/R-CFA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Canis familiaris 43474 R-CFA-6801342 https://reactome.org/PathwayBrowser/#/R-CFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Canis familiaris 43474 R-CFA-6801456 https://reactome.org/PathwayBrowser/#/R-CFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Canis familiaris 43474 R-CFA-6803545 https://reactome.org/PathwayBrowser/#/R-CFA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Canis familiaris 43474 R-CFA-6806967 https://reactome.org/PathwayBrowser/#/R-CFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Canis familiaris 43474 R-CFA-6807008 https://reactome.org/PathwayBrowser/#/R-CFA-6807008 PTPRJ dephosphorylates MET IEA Canis familiaris 43474 R-CFA-6807027 https://reactome.org/PathwayBrowser/#/R-CFA-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Canis familiaris 43474 R-CFA-6809015 https://reactome.org/PathwayBrowser/#/R-CFA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Canis familiaris 43474 R-CFA-6809320 https://reactome.org/PathwayBrowser/#/R-CFA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Canis familiaris 43474 R-CFA-6809325 https://reactome.org/PathwayBrowser/#/R-CFA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Canis familiaris 43474 R-CFA-6809720 https://reactome.org/PathwayBrowser/#/R-CFA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Canis familiaris 43474 R-CFA-6809777 https://reactome.org/PathwayBrowser/#/R-CFA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Canis familiaris 43474 R-CFA-6809778 https://reactome.org/PathwayBrowser/#/R-CFA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Canis familiaris 43474 R-CFA-6810410 https://reactome.org/PathwayBrowser/#/R-CFA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Canis familiaris 43474 R-CFA-6811422 https://reactome.org/PathwayBrowser/#/R-CFA-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Canis familiaris 43474 R-CFA-6814120 https://reactome.org/PathwayBrowser/#/R-CFA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Canis familiaris 43474 R-CFA-69199 https://reactome.org/PathwayBrowser/#/R-CFA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Canis familiaris 43474 R-CFA-70262 https://reactome.org/PathwayBrowser/#/R-CFA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Canis familiaris 43474 R-CFA-70449 https://reactome.org/PathwayBrowser/#/R-CFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Canis familiaris 43474 R-CFA-70479 https://reactome.org/PathwayBrowser/#/R-CFA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Canis familiaris 43474 R-CFA-70482 https://reactome.org/PathwayBrowser/#/R-CFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Canis familiaris 43474 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 43474 R-CFA-70555 https://reactome.org/PathwayBrowser/#/R-CFA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Canis familiaris 43474 R-CFA-70560 https://reactome.org/PathwayBrowser/#/R-CFA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Canis familiaris 43474 R-CFA-70606 https://reactome.org/PathwayBrowser/#/R-CFA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Canis familiaris 43474 R-CFA-70773 https://reactome.org/PathwayBrowser/#/R-CFA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Canis familiaris 43474 R-CFA-70997 https://reactome.org/PathwayBrowser/#/R-CFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Canis familiaris 43474 R-CFA-71031 https://reactome.org/PathwayBrowser/#/R-CFA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Canis familiaris 43474 R-CFA-71590 https://reactome.org/PathwayBrowser/#/R-CFA-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Canis familiaris 43474 R-CFA-71732 https://reactome.org/PathwayBrowser/#/R-CFA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Canis familiaris 43474 R-CFA-71775 https://reactome.org/PathwayBrowser/#/R-CFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Canis familiaris 43474 R-CFA-71825 https://reactome.org/PathwayBrowser/#/R-CFA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Canis familiaris 43474 R-CFA-72619 https://reactome.org/PathwayBrowser/#/R-CFA-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Canis familiaris 43474 R-CFA-72621 https://reactome.org/PathwayBrowser/#/R-CFA-72621 Ribosomal scanning IEA Canis familiaris 43474 R-CFA-72647 https://reactome.org/PathwayBrowser/#/R-CFA-72647 Cap-bound mRNA is activated by helicases IEA Canis familiaris 43474 R-CFA-72671 https://reactome.org/PathwayBrowser/#/R-CFA-72671 eIF5B:GTP is hydrolyzed and released IEA Canis familiaris 43474 R-CFA-73573 https://reactome.org/PathwayBrowser/#/R-CFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Canis familiaris 43474 R-CFA-73577 https://reactome.org/PathwayBrowser/#/R-CFA-73577 CAD hexamer transforms L-Gln to CAP IEA Canis familiaris 43474 R-CFA-73647 https://reactome.org/PathwayBrowser/#/R-CFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Canis familiaris 43474 R-CFA-73805 https://reactome.org/PathwayBrowser/#/R-CFA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Canis familiaris 43474 R-CFA-73810 https://reactome.org/PathwayBrowser/#/R-CFA-73810 FGAM + ATP => AIR + ADP + Pi IEA Canis familiaris 43474 R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 43474 R-CFA-73814 https://reactome.org/PathwayBrowser/#/R-CFA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Canis familiaris 43474 R-CFA-74242 https://reactome.org/PathwayBrowser/#/R-CFA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Canis familiaris 43474 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 43474 R-CFA-74249 https://reactome.org/PathwayBrowser/#/R-CFA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Canis familiaris 43474 R-CFA-74372 https://reactome.org/PathwayBrowser/#/R-CFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Canis familiaris 43474 R-CFA-74376 https://reactome.org/PathwayBrowser/#/R-CFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Canis familiaris 43474 R-CFA-74733 https://reactome.org/PathwayBrowser/#/R-CFA-74733 Insulin receptor de-phosphorylation IEA Canis familiaris 43474 R-CFA-74948 https://reactome.org/PathwayBrowser/#/R-CFA-74948 PP2A dephosphorylates p-RHO to RHO IEA Canis familiaris 43474 R-CFA-75848 https://reactome.org/PathwayBrowser/#/R-CFA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Canis familiaris 43474 R-CFA-75851 https://reactome.org/PathwayBrowser/#/R-CFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 43474 R-CFA-75899 https://reactome.org/PathwayBrowser/#/R-CFA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Canis familiaris 43474 R-CFA-75949 https://reactome.org/PathwayBrowser/#/R-CFA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Canis familiaris 43474 R-CFA-77078 https://reactome.org/PathwayBrowser/#/R-CFA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Canis familiaris 43474 R-CFA-8848053 https://reactome.org/PathwayBrowser/#/R-CFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Canis familiaris 43474 R-CFA-8849082 https://reactome.org/PathwayBrowser/#/R-CFA-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Canis familiaris 43474 R-CFA-8849969 https://reactome.org/PathwayBrowser/#/R-CFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Canis familiaris 43474 R-CFA-8850846 https://reactome.org/PathwayBrowser/#/R-CFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Canis familiaris 43474 R-CFA-8850854 https://reactome.org/PathwayBrowser/#/R-CFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Canis familiaris 43474 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 43474 R-CFA-8851110 https://reactome.org/PathwayBrowser/#/R-CFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Canis familiaris 43474 R-CFA-8851129 https://reactome.org/PathwayBrowser/#/R-CFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Canis familiaris 43474 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 43474 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 43474 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 43474 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 43474 R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 43474 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 43474 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 43474 R-CFA-8852200 https://reactome.org/PathwayBrowser/#/R-CFA-8852200 Inactivation of LCK by PTPN22 IEA Canis familiaris 43474 R-CFA-8854173 https://reactome.org/PathwayBrowser/#/R-CFA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Canis familiaris 43474 R-CFA-8854255 https://reactome.org/PathwayBrowser/#/R-CFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 43474 R-CFA-8854329 https://reactome.org/PathwayBrowser/#/R-CFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 43474 R-CFA-8854604 https://reactome.org/PathwayBrowser/#/R-CFA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Canis familiaris 43474 R-CFA-8854612 https://reactome.org/PathwayBrowser/#/R-CFA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Canis familiaris 43474 R-CFA-8855381 https://reactome.org/PathwayBrowser/#/R-CFA-8855381 PTPN22 dephosphorylates ZAP70 IEA Canis familiaris 43474 R-CFA-8863804 https://reactome.org/PathwayBrowser/#/R-CFA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Canis familiaris 43474 R-CFA-8864029 https://reactome.org/PathwayBrowser/#/R-CFA-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Canis familiaris 43474 R-CFA-8864036 https://reactome.org/PathwayBrowser/#/R-CFA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Canis familiaris 43474 R-CFA-8864125 https://reactome.org/PathwayBrowser/#/R-CFA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Canis familiaris 43474 R-CFA-8865774 https://reactome.org/PathwayBrowser/#/R-CFA-8865774 TTLLs polyglutamylate tubulin IEA Canis familiaris 43474 R-CFA-8866542 https://reactome.org/PathwayBrowser/#/R-CFA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Canis familiaris 43474 R-CFA-8867047 https://reactome.org/PathwayBrowser/#/R-CFA-8867047 PTPN3 dephosphorylates EPS15 IEA Canis familiaris 43474 R-CFA-8867370 https://reactome.org/PathwayBrowser/#/R-CFA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Canis familiaris 43474 R-CFA-8867658 https://reactome.org/PathwayBrowser/#/R-CFA-8867658 PTPN3 dephosphorylates MAPK12 IEA Canis familiaris 43474 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 43474 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 43474 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 43474 R-CFA-8876889 https://reactome.org/PathwayBrowser/#/R-CFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 43474 R-CFA-8878654 https://reactome.org/PathwayBrowser/#/R-CFA-8878654 ACP6 hydrolyses MYS-LPA IEA Canis familiaris 43474 R-CFA-8878787 https://reactome.org/PathwayBrowser/#/R-CFA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Canis familiaris 43474 R-CFA-8937767 https://reactome.org/PathwayBrowser/#/R-CFA-8937767 PTPN11 dephosphorylates RUNX1 IEA Canis familiaris 43474 R-CFA-8940070 https://reactome.org/PathwayBrowser/#/R-CFA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Canis familiaris 43474 R-CFA-8940074 https://reactome.org/PathwayBrowser/#/R-CFA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Canis familiaris 43474 R-CFA-8951498 https://reactome.org/PathwayBrowser/#/R-CFA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Canis familiaris 43474 R-CFA-8952137 https://reactome.org/PathwayBrowser/#/R-CFA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Canis familiaris 43474 R-CFA-8953499 https://reactome.org/PathwayBrowser/#/R-CFA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Canis familiaris 43474 R-CFA-8959510 https://reactome.org/PathwayBrowser/#/R-CFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Canis familiaris 43474 R-CFA-8981637 https://reactome.org/PathwayBrowser/#/R-CFA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Canis familiaris 43474 R-CFA-8982020 https://reactome.org/PathwayBrowser/#/R-CFA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Canis familiaris 43474 R-CFA-8982021 https://reactome.org/PathwayBrowser/#/R-CFA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Canis familiaris 43474 R-CFA-8982025 https://reactome.org/PathwayBrowser/#/R-CFA-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Canis familiaris 43474 R-CFA-8985594 https://reactome.org/PathwayBrowser/#/R-CFA-8985594 MYO9B inactivates RHOA IEA Canis familiaris 43474 R-CFA-9013022 https://reactome.org/PathwayBrowser/#/R-CFA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Canis familiaris 43474 R-CFA-9013111 https://reactome.org/PathwayBrowser/#/R-CFA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Canis familiaris 43474 R-CFA-9013144 https://reactome.org/PathwayBrowser/#/R-CFA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Canis familiaris 43474 R-CFA-9013161 https://reactome.org/PathwayBrowser/#/R-CFA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Canis familiaris 43474 R-CFA-9013437 https://reactome.org/PathwayBrowser/#/R-CFA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Canis familiaris 43474 R-CFA-9014295 https://reactome.org/PathwayBrowser/#/R-CFA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Canis familiaris 43474 R-CFA-9014434 https://reactome.org/PathwayBrowser/#/R-CFA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Canis familiaris 43474 R-CFA-9017488 https://reactome.org/PathwayBrowser/#/R-CFA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Canis familiaris 43474 R-CFA-9018745 https://reactome.org/PathwayBrowser/#/R-CFA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Canis familiaris 43474 R-CFA-9018806 https://reactome.org/PathwayBrowser/#/R-CFA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Canis familiaris 43474 R-CFA-9018814 https://reactome.org/PathwayBrowser/#/R-CFA-9018814 RHOT1 hydrolyzes GTP IEA Canis familiaris 43474 R-CFA-917841 https://reactome.org/PathwayBrowser/#/R-CFA-917841 Acidification of Tf:TfR1 containing endosome IEA Canis familiaris 43474 R-CFA-917979 https://reactome.org/PathwayBrowser/#/R-CFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-936802 https://reactome.org/PathwayBrowser/#/R-CFA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Canis familiaris 43474 R-CFA-936883 https://reactome.org/PathwayBrowser/#/R-CFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Canis familiaris 43474 R-CFA-936895 https://reactome.org/PathwayBrowser/#/R-CFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Canis familiaris 43474 R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 43474 R-CFA-937311 https://reactome.org/PathwayBrowser/#/R-CFA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Canis familiaris 43474 R-CFA-939763 https://reactome.org/PathwayBrowser/#/R-CFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Canis familiaris 43474 R-CFA-947591 https://reactome.org/PathwayBrowser/#/R-CFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Canis familiaris 43474 R-CFA-9624893 https://reactome.org/PathwayBrowser/#/R-CFA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Canis familiaris 43474 R-CFA-9640195 https://reactome.org/PathwayBrowser/#/R-CFA-9640195 RRAGA,B hydrolyzes GTP IEA Canis familiaris 43474 R-CFA-9645598 https://reactome.org/PathwayBrowser/#/R-CFA-9645598 RRAGC,D hydrolyzes GTP IEA Canis familiaris 43474 R-CFA-965067 https://reactome.org/PathwayBrowser/#/R-CFA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Canis familiaris 43474 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 43474 R-CFA-9661417 https://reactome.org/PathwayBrowser/#/R-CFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-9668419 https://reactome.org/PathwayBrowser/#/R-CFA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Canis familiaris 43474 R-CFA-9674816 https://reactome.org/PathwayBrowser/#/R-CFA-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Canis familiaris 43474 R-CFA-9684118 https://reactome.org/PathwayBrowser/#/R-CFA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Canis familiaris 43474 R-CFA-9686524 https://reactome.org/PathwayBrowser/#/R-CFA-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Canis familiaris 43474 R-CFA-9693282 https://reactome.org/PathwayBrowser/#/R-CFA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Canis familiaris 43474 R-CFA-9698408 https://reactome.org/PathwayBrowser/#/R-CFA-9698408 PTPRJ dephosphorylates active FLT3 IEA Canis familiaris 43474 R-CFA-9700200 https://reactome.org/PathwayBrowser/#/R-CFA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Canis familiaris 43474 R-CFA-9701507 https://reactome.org/PathwayBrowser/#/R-CFA-9701507 PTPN6 dephosphorylates JAK3 IEA Canis familiaris 43474 R-CFA-9706399 https://reactome.org/PathwayBrowser/#/R-CFA-9706399 RHOBTB3 hydrolyzes ATP IEA Canis familiaris 43474 R-CFA-9727198 https://reactome.org/PathwayBrowser/#/R-CFA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Canis familiaris 43474 R-CFA-9750546 https://reactome.org/PathwayBrowser/#/R-CFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-9750617 https://reactome.org/PathwayBrowser/#/R-CFA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-9750656 https://reactome.org/PathwayBrowser/#/R-CFA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Canis familiaris 43474 R-CFA-9753278 https://reactome.org/PathwayBrowser/#/R-CFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 43474 R-CFA-9753283 https://reactome.org/PathwayBrowser/#/R-CFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 43474 R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 43474 R-CFA-9759206 https://reactome.org/PathwayBrowser/#/R-CFA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Canis familiaris 43474 R-CFA-9759454 https://reactome.org/PathwayBrowser/#/R-CFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Canis familiaris 43474 R-CFA-9759461 https://reactome.org/PathwayBrowser/#/R-CFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Canis familiaris 43474 R-CFA-9770141 https://reactome.org/PathwayBrowser/#/R-CFA-9770141 Formation of the Spliceosomal C* complex IEA Canis familiaris 43474 R-CFA-9770142 https://reactome.org/PathwayBrowser/#/R-CFA-9770142 Formation of the Spliceosomal B complex IEA Canis familiaris 43474 R-CFA-977324 https://reactome.org/PathwayBrowser/#/R-CFA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Canis familiaris 43474 R-CFA-9837419 https://reactome.org/PathwayBrowser/#/R-CFA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Canis familiaris 43474 R-CFA-9838004 https://reactome.org/PathwayBrowser/#/R-CFA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Canis familiaris 43474 R-CFA-9838081 https://reactome.org/PathwayBrowser/#/R-CFA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Canis familiaris 43474 R-CFA-9838289 https://reactome.org/PathwayBrowser/#/R-CFA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Canis familiaris 43474 R-CFA-9839059 https://reactome.org/PathwayBrowser/#/R-CFA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Canis familiaris 43474 R-CFA-9839105 https://reactome.org/PathwayBrowser/#/R-CFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Canis familiaris 43474 R-CFA-9839113 https://reactome.org/PathwayBrowser/#/R-CFA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Canis familiaris 43474 R-CFA-9843721 https://reactome.org/PathwayBrowser/#/R-CFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Canis familiaris 43474 R-CFA-9853385 https://reactome.org/PathwayBrowser/#/R-CFA-9853385 PPP1CC dephosphorylates PLK1 IEA Canis familiaris 43474 R-CFA-9861725 https://reactome.org/PathwayBrowser/#/R-CFA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Canis familiaris 43474 R-CFA-997309 https://reactome.org/PathwayBrowser/#/R-CFA-997309 Dephosphorylation of STAT1 by SHP2 IEA Canis familiaris 43474 R-CFA-997311 https://reactome.org/PathwayBrowser/#/R-CFA-997311 Dephosphorylation of TYK2 by PTP1B IEA Canis familiaris 43474 R-CFA-997314 https://reactome.org/PathwayBrowser/#/R-CFA-997314 Dephosphorylation of JAK1 by SHP1 IEA Canis familiaris 43474 R-CFA-997326 https://reactome.org/PathwayBrowser/#/R-CFA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Canis familiaris 43474 R-DDI-111215 https://reactome.org/PathwayBrowser/#/R-DDI-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Dictyostelium discoideum 43474 R-DDI-111524 https://reactome.org/PathwayBrowser/#/R-DDI-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Dictyostelium discoideum 43474 R-DDI-112037 https://reactome.org/PathwayBrowser/#/R-DDI-112037 Inactivation of PLC beta IEA Dictyostelium discoideum 43474 R-DDI-113503 https://reactome.org/PathwayBrowser/#/R-DDI-113503 PP2A mediated localization of RB1 protein in chromatin IEA Dictyostelium discoideum 43474 R-DDI-1237129 https://reactome.org/PathwayBrowser/#/R-DDI-1237129 Acireductone is created IEA Dictyostelium discoideum 43474 R-DDI-1247935 https://reactome.org/PathwayBrowser/#/R-DDI-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Dictyostelium discoideum 43474 R-DDI-1363274 https://reactome.org/PathwayBrowser/#/R-DDI-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Dictyostelium discoideum 43474 R-DDI-1363276 https://reactome.org/PathwayBrowser/#/R-DDI-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Dictyostelium discoideum 43474 R-DDI-1369028 https://reactome.org/PathwayBrowser/#/R-DDI-1369028 ABCAs mediate lipid efflux IEA Dictyostelium discoideum 43474 R-DDI-1369052 https://reactome.org/PathwayBrowser/#/R-DDI-1369052 ABCAs mediate lipid influx IEA Dictyostelium discoideum 43474 R-DDI-1454916 https://reactome.org/PathwayBrowser/#/R-DDI-1454916 The ABCC family mediates organic anion transport IEA Dictyostelium discoideum 43474 R-DDI-1454928 https://reactome.org/PathwayBrowser/#/R-DDI-1454928 ABCG4 may mediate cholesterol efflux IEA Dictyostelium discoideum 43474 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-1467466 https://reactome.org/PathwayBrowser/#/R-DDI-1467466 ABCA4 mediates atRAL transport IEA Dictyostelium discoideum 43474 R-DDI-1483203 https://reactome.org/PathwayBrowser/#/R-DDI-1483203 PA is dephosphorylated to DAG by LPIN IEA Dictyostelium discoideum 43474 R-DDI-1675795 https://reactome.org/PathwayBrowser/#/R-DDI-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Dictyostelium discoideum 43474 R-DDI-1675824 https://reactome.org/PathwayBrowser/#/R-DDI-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Dictyostelium discoideum 43474 R-DDI-1675836 https://reactome.org/PathwayBrowser/#/R-DDI-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-1675949 https://reactome.org/PathwayBrowser/#/R-DDI-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-1675988 https://reactome.org/PathwayBrowser/#/R-DDI-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-1675994 https://reactome.org/PathwayBrowser/#/R-DDI-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-1676065 https://reactome.org/PathwayBrowser/#/R-DDI-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Dictyostelium discoideum 43474 R-DDI-1676105 https://reactome.org/PathwayBrowser/#/R-DDI-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Dictyostelium discoideum 43474 R-DDI-1676114 https://reactome.org/PathwayBrowser/#/R-DDI-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Dictyostelium discoideum 43474 R-DDI-1676124 https://reactome.org/PathwayBrowser/#/R-DDI-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Dictyostelium discoideum 43474 R-DDI-1676133 https://reactome.org/PathwayBrowser/#/R-DDI-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Dictyostelium discoideum 43474 R-DDI-1676141 https://reactome.org/PathwayBrowser/#/R-DDI-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Dictyostelium discoideum 43474 R-DDI-1676149 https://reactome.org/PathwayBrowser/#/R-DDI-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-1676177 https://reactome.org/PathwayBrowser/#/R-DDI-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-1676203 https://reactome.org/PathwayBrowser/#/R-DDI-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-1676204 https://reactome.org/PathwayBrowser/#/R-DDI-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Dictyostelium discoideum 43474 R-DDI-170666 https://reactome.org/PathwayBrowser/#/R-DDI-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Dictyostelium discoideum 43474 R-DDI-170685 https://reactome.org/PathwayBrowser/#/R-DDI-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Dictyostelium discoideum 43474 R-DDI-170686 https://reactome.org/PathwayBrowser/#/R-DDI-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Dictyostelium discoideum 43474 R-DDI-174391 https://reactome.org/PathwayBrowser/#/R-DDI-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Dictyostelium discoideum 43474 R-DDI-174394 https://reactome.org/PathwayBrowser/#/R-DDI-174394 GSS:Mg2+ dimer synthesizes GSH IEA Dictyostelium discoideum 43474 R-DDI-176606 https://reactome.org/PathwayBrowser/#/R-DDI-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Dictyostelium discoideum 43474 R-DDI-1855154 https://reactome.org/PathwayBrowser/#/R-DDI-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855159 https://reactome.org/PathwayBrowser/#/R-DDI-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855163 https://reactome.org/PathwayBrowser/#/R-DDI-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 43474 R-DDI-1855165 https://reactome.org/PathwayBrowser/#/R-DDI-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855166 https://reactome.org/PathwayBrowser/#/R-DDI-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855171 https://reactome.org/PathwayBrowser/#/R-DDI-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855174 https://reactome.org/PathwayBrowser/#/R-DDI-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855198 https://reactome.org/PathwayBrowser/#/R-DDI-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855200 https://reactome.org/PathwayBrowser/#/R-DDI-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 43474 R-DDI-1855205 https://reactome.org/PathwayBrowser/#/R-DDI-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855208 https://reactome.org/PathwayBrowser/#/R-DDI-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855210 https://reactome.org/PathwayBrowser/#/R-DDI-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855211 https://reactome.org/PathwayBrowser/#/R-DDI-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855213 https://reactome.org/PathwayBrowser/#/R-DDI-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-1855218 https://reactome.org/PathwayBrowser/#/R-DDI-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855219 https://reactome.org/PathwayBrowser/#/R-DDI-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-1855222 https://reactome.org/PathwayBrowser/#/R-DDI-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-1855225 https://reactome.org/PathwayBrowser/#/R-DDI-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 43474 R-DDI-1855232 https://reactome.org/PathwayBrowser/#/R-DDI-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-191414 https://reactome.org/PathwayBrowser/#/R-DDI-191414 MVD decarboxylates MVA5PP to IPPP IEA Dictyostelium discoideum 43474 R-DDI-193362 https://reactome.org/PathwayBrowser/#/R-DDI-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-194153 https://reactome.org/PathwayBrowser/#/R-DDI-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-197958 https://reactome.org/PathwayBrowser/#/R-DDI-197958 FPGS-2 transforms THF to THFPG IEA Dictyostelium discoideum 43474 R-DDI-199456 https://reactome.org/PathwayBrowser/#/R-DDI-199456 PTEN dephosphorylates PIP3 IEA Dictyostelium discoideum 43474 R-DDI-199959 https://reactome.org/PathwayBrowser/#/R-DDI-199959 ERKs are inactivated by protein phosphatase 2A IEA Dictyostelium discoideum 43474 R-DDI-200555 https://reactome.org/PathwayBrowser/#/R-DDI-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Dictyostelium discoideum 43474 R-DDI-200681 https://reactome.org/PathwayBrowser/#/R-DDI-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Dictyostelium discoideum 43474 R-DDI-200682 https://reactome.org/PathwayBrowser/#/R-DDI-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Dictyostelium discoideum 43474 R-DDI-200711 https://reactome.org/PathwayBrowser/#/R-DDI-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Dictyostelium discoideum 43474 R-DDI-2023971 https://reactome.org/PathwayBrowser/#/R-DDI-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-2023973 https://reactome.org/PathwayBrowser/#/R-DDI-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-2029468 https://reactome.org/PathwayBrowser/#/R-DDI-2029468 Conversion of PA into DAG by PAP-1 IEA Dictyostelium discoideum 43474 R-DDI-203797 https://reactome.org/PathwayBrowser/#/R-DDI-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Dictyostelium discoideum 43474 R-DDI-2046093 https://reactome.org/PathwayBrowser/#/R-DDI-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Dictyostelium discoideum 43474 R-DDI-2408551 https://reactome.org/PathwayBrowser/#/R-DDI-2408551 SeMet is converted to AdoSeMet by MAT IEA Dictyostelium discoideum 43474 R-DDI-2529015 https://reactome.org/PathwayBrowser/#/R-DDI-2529015 Dephosphorylation of CK2-modified condensin I IEA Dictyostelium discoideum 43474 R-DDI-265783 https://reactome.org/PathwayBrowser/#/R-DDI-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-266082 https://reactome.org/PathwayBrowser/#/R-DDI-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Dictyostelium discoideum 43474 R-DDI-2872498 https://reactome.org/PathwayBrowser/#/R-DDI-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Dictyostelium discoideum 43474 R-DDI-3095901 https://reactome.org/PathwayBrowser/#/R-DDI-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-3371422 https://reactome.org/PathwayBrowser/#/R-DDI-3371422 ATP hydrolysis by HSP70 IEA Dictyostelium discoideum 43474 R-DDI-372843 https://reactome.org/PathwayBrowser/#/R-DDI-372843 SLC25A10 mediates exchange of malate and phosphate IEA Dictyostelium discoideum 43474 R-DDI-380979 https://reactome.org/PathwayBrowser/#/R-DDI-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Dictyostelium discoideum 43474 R-DDI-382560 https://reactome.org/PathwayBrowser/#/R-DDI-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Dictyostelium discoideum 43474 R-DDI-382575 https://reactome.org/PathwayBrowser/#/R-DDI-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Dictyostelium discoideum 43474 R-DDI-383190 https://reactome.org/PathwayBrowser/#/R-DDI-383190 HCO3- transport through ion channel IEA Dictyostelium discoideum 43474 R-DDI-390329 https://reactome.org/PathwayBrowser/#/R-DDI-390329 Dephosphorylation of AKT by PP2A IEA Dictyostelium discoideum 43474 R-DDI-428609 https://reactome.org/PathwayBrowser/#/R-DDI-428609 Type I Na+-coupled phosphate co-transport IEA Dictyostelium discoideum 43474 R-DDI-428664 https://reactome.org/PathwayBrowser/#/R-DDI-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Dictyostelium discoideum 43474 R-DDI-428690 https://reactome.org/PathwayBrowser/#/R-DDI-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Dictyostelium discoideum 43474 R-DDI-428696 https://reactome.org/PathwayBrowser/#/R-DDI-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Dictyostelium discoideum 43474 R-DDI-429157 https://reactome.org/PathwayBrowser/#/R-DDI-429157 ABCC4 accumulation of dense granule contents IEA Dictyostelium discoideum 43474 R-DDI-446200 https://reactome.org/PathwayBrowser/#/R-DDI-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Dictyostelium discoideum 43474 R-DDI-449937 https://reactome.org/PathwayBrowser/#/R-DDI-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Dictyostelium discoideum 43474 R-DDI-453339 https://reactome.org/PathwayBrowser/#/R-DDI-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Dictyostelium discoideum 43474 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 43474 R-DDI-504054 https://reactome.org/PathwayBrowser/#/R-DDI-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Dictyostelium discoideum 43474 R-DDI-508308 https://reactome.org/PathwayBrowser/#/R-DDI-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Dictyostelium discoideum 43474 R-DDI-5221130 https://reactome.org/PathwayBrowser/#/R-DDI-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Dictyostelium discoideum 43474 R-DDI-5223313 https://reactome.org/PathwayBrowser/#/R-DDI-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Dictyostelium discoideum 43474 R-DDI-5251955 https://reactome.org/PathwayBrowser/#/R-DDI-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Dictyostelium discoideum 43474 R-DDI-5251959 https://reactome.org/PathwayBrowser/#/R-DDI-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Dictyostelium discoideum 43474 R-DDI-5251989 https://reactome.org/PathwayBrowser/#/R-DDI-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Dictyostelium discoideum 43474 R-DDI-5603114 https://reactome.org/PathwayBrowser/#/R-DDI-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Dictyostelium discoideum 43474 R-DDI-5649705 https://reactome.org/PathwayBrowser/#/R-DDI-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Dictyostelium discoideum 43474 R-DDI-5675373 https://reactome.org/PathwayBrowser/#/R-DDI-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Dictyostelium discoideum 43474 R-DDI-5675376 https://reactome.org/PathwayBrowser/#/R-DDI-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Dictyostelium discoideum 43474 R-DDI-5678706 https://reactome.org/PathwayBrowser/#/R-DDI-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-5678863 https://reactome.org/PathwayBrowser/#/R-DDI-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-5679041 https://reactome.org/PathwayBrowser/#/R-DDI-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-5682285 https://reactome.org/PathwayBrowser/#/R-DDI-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-5683405 https://reactome.org/PathwayBrowser/#/R-DDI-5683405 PPP5C dephosphorylates TP53BP1 IEA Dictyostelium discoideum 43474 R-DDI-5683714 https://reactome.org/PathwayBrowser/#/R-DDI-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Dictyostelium discoideum 43474 R-DDI-5683925 https://reactome.org/PathwayBrowser/#/R-DDI-5683925 ULK1 is dephosphorylated IEA Dictyostelium discoideum 43474 R-DDI-5690996 https://reactome.org/PathwayBrowser/#/R-DDI-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Dictyostelium discoideum 43474 R-DDI-5692462 https://reactome.org/PathwayBrowser/#/R-DDI-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Dictyostelium discoideum 43474 R-DDI-5692480 https://reactome.org/PathwayBrowser/#/R-DDI-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Dictyostelium discoideum 43474 R-DDI-5694421 https://reactome.org/PathwayBrowser/#/R-DDI-5694421 PP6 dephosphorylates SEC24 IEA Dictyostelium discoideum 43474 R-DDI-5694425 https://reactome.org/PathwayBrowser/#/R-DDI-5694425 NSF ATPase activity dissociates cis-SNARE IEA Dictyostelium discoideum 43474 R-DDI-5694527 https://reactome.org/PathwayBrowser/#/R-DDI-5694527 Loss of SAR1B GTPase IEA Dictyostelium discoideum 43474 R-DDI-5696839 https://reactome.org/PathwayBrowser/#/R-DDI-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Dictyostelium discoideum 43474 R-DDI-6782131 https://reactome.org/PathwayBrowser/#/R-DDI-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Dictyostelium discoideum 43474 R-DDI-6797630 https://reactome.org/PathwayBrowser/#/R-DDI-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Dictyostelium discoideum 43474 R-DDI-6801456 https://reactome.org/PathwayBrowser/#/R-DDI-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Dictyostelium discoideum 43474 R-DDI-6806967 https://reactome.org/PathwayBrowser/#/R-DDI-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Dictyostelium discoideum 43474 R-DDI-6809015 https://reactome.org/PathwayBrowser/#/R-DDI-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Dictyostelium discoideum 43474 R-DDI-6809320 https://reactome.org/PathwayBrowser/#/R-DDI-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-6809325 https://reactome.org/PathwayBrowser/#/R-DDI-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-6809720 https://reactome.org/PathwayBrowser/#/R-DDI-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Dictyostelium discoideum 43474 R-DDI-6809777 https://reactome.org/PathwayBrowser/#/R-DDI-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Dictyostelium discoideum 43474 R-DDI-6809778 https://reactome.org/PathwayBrowser/#/R-DDI-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Dictyostelium discoideum 43474 R-DDI-6811422 https://reactome.org/PathwayBrowser/#/R-DDI-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Dictyostelium discoideum 43474 R-DDI-6811504 https://reactome.org/PathwayBrowser/#/R-DDI-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Dictyostelium discoideum 43474 R-DDI-6814120 https://reactome.org/PathwayBrowser/#/R-DDI-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Dictyostelium discoideum 43474 R-DDI-70262 https://reactome.org/PathwayBrowser/#/R-DDI-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Dictyostelium discoideum 43474 R-DDI-70449 https://reactome.org/PathwayBrowser/#/R-DDI-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Dictyostelium discoideum 43474 R-DDI-70479 https://reactome.org/PathwayBrowser/#/R-DDI-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Dictyostelium discoideum 43474 R-DDI-70482 https://reactome.org/PathwayBrowser/#/R-DDI-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Dictyostelium discoideum 43474 R-DDI-70773 https://reactome.org/PathwayBrowser/#/R-DDI-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Dictyostelium discoideum 43474 R-DDI-70997 https://reactome.org/PathwayBrowser/#/R-DDI-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Dictyostelium discoideum 43474 R-DDI-71031 https://reactome.org/PathwayBrowser/#/R-DDI-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Dictyostelium discoideum 43474 R-DDI-71590 https://reactome.org/PathwayBrowser/#/R-DDI-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Dictyostelium discoideum 43474 R-DDI-71732 https://reactome.org/PathwayBrowser/#/R-DDI-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Dictyostelium discoideum 43474 R-DDI-71775 https://reactome.org/PathwayBrowser/#/R-DDI-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Dictyostelium discoideum 43474 R-DDI-72621 https://reactome.org/PathwayBrowser/#/R-DDI-72621 Ribosomal scanning IEA Dictyostelium discoideum 43474 R-DDI-72671 https://reactome.org/PathwayBrowser/#/R-DDI-72671 eIF5B:GTP is hydrolyzed and released IEA Dictyostelium discoideum 43474 R-DDI-73573 https://reactome.org/PathwayBrowser/#/R-DDI-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Dictyostelium discoideum 43474 R-DDI-73577 https://reactome.org/PathwayBrowser/#/R-DDI-73577 CAD hexamer transforms L-Gln to CAP IEA Dictyostelium discoideum 43474 R-DDI-73647 https://reactome.org/PathwayBrowser/#/R-DDI-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Dictyostelium discoideum 43474 R-DDI-73810 https://reactome.org/PathwayBrowser/#/R-DDI-73810 FGAM + ATP => AIR + ADP + Pi IEA Dictyostelium discoideum 43474 R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 43474 R-DDI-73814 https://reactome.org/PathwayBrowser/#/R-DDI-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Dictyostelium discoideum 43474 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 43474 R-DDI-74372 https://reactome.org/PathwayBrowser/#/R-DDI-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Dictyostelium discoideum 43474 R-DDI-74376 https://reactome.org/PathwayBrowser/#/R-DDI-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Dictyostelium discoideum 43474 R-DDI-75848 https://reactome.org/PathwayBrowser/#/R-DDI-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Dictyostelium discoideum 43474 R-DDI-75851 https://reactome.org/PathwayBrowser/#/R-DDI-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 43474 R-DDI-75899 https://reactome.org/PathwayBrowser/#/R-DDI-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Dictyostelium discoideum 43474 R-DDI-75949 https://reactome.org/PathwayBrowser/#/R-DDI-75949 RNA Polymerase II Promoter Opening: First Transition IEA Dictyostelium discoideum 43474 R-DDI-77078 https://reactome.org/PathwayBrowser/#/R-DDI-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Dictyostelium discoideum 43474 R-DDI-8848053 https://reactome.org/PathwayBrowser/#/R-DDI-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Dictyostelium discoideum 43474 R-DDI-8849969 https://reactome.org/PathwayBrowser/#/R-DDI-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Dictyostelium discoideum 43474 R-DDI-8854173 https://reactome.org/PathwayBrowser/#/R-DDI-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Dictyostelium discoideum 43474 R-DDI-8854255 https://reactome.org/PathwayBrowser/#/R-DDI-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 43474 R-DDI-8854329 https://reactome.org/PathwayBrowser/#/R-DDI-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 43474 R-DDI-8854604 https://reactome.org/PathwayBrowser/#/R-DDI-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Dictyostelium discoideum 43474 R-DDI-8854612 https://reactome.org/PathwayBrowser/#/R-DDI-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Dictyostelium discoideum 43474 R-DDI-8867370 https://reactome.org/PathwayBrowser/#/R-DDI-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Dictyostelium discoideum 43474 R-DDI-8876889 https://reactome.org/PathwayBrowser/#/R-DDI-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 43474 R-DDI-8878654 https://reactome.org/PathwayBrowser/#/R-DDI-8878654 ACP6 hydrolyses MYS-LPA IEA Dictyostelium discoideum 43474 R-DDI-8952137 https://reactome.org/PathwayBrowser/#/R-DDI-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Dictyostelium discoideum 43474 R-DDI-8953499 https://reactome.org/PathwayBrowser/#/R-DDI-8953499 IMPAD1 hydrolyses PAP to AMP IEA Dictyostelium discoideum 43474 R-DDI-8959510 https://reactome.org/PathwayBrowser/#/R-DDI-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Dictyostelium discoideum 43474 R-DDI-8982020 https://reactome.org/PathwayBrowser/#/R-DDI-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Dictyostelium discoideum 43474 R-DDI-8982021 https://reactome.org/PathwayBrowser/#/R-DDI-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Dictyostelium discoideum 43474 R-DDI-8982025 https://reactome.org/PathwayBrowser/#/R-DDI-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Dictyostelium discoideum 43474 R-DDI-9013144 https://reactome.org/PathwayBrowser/#/R-DDI-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Dictyostelium discoideum 43474 R-DDI-9013161 https://reactome.org/PathwayBrowser/#/R-DDI-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Dictyostelium discoideum 43474 R-DDI-9014295 https://reactome.org/PathwayBrowser/#/R-DDI-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Dictyostelium discoideum 43474 R-DDI-9017488 https://reactome.org/PathwayBrowser/#/R-DDI-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Dictyostelium discoideum 43474 R-DDI-9018745 https://reactome.org/PathwayBrowser/#/R-DDI-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Dictyostelium discoideum 43474 R-DDI-9018806 https://reactome.org/PathwayBrowser/#/R-DDI-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Dictyostelium discoideum 43474 R-DDI-9018814 https://reactome.org/PathwayBrowser/#/R-DDI-9018814 RHOT1 hydrolyzes GTP IEA Dictyostelium discoideum 43474 R-DDI-9018826 https://reactome.org/PathwayBrowser/#/R-DDI-9018826 RHOT2 hydrolyzes GTP IEA Dictyostelium discoideum 43474 R-DDI-917693 https://reactome.org/PathwayBrowser/#/R-DDI-917693 ESCRT Disassembly IEA Dictyostelium discoideum 43474 R-DDI-917841 https://reactome.org/PathwayBrowser/#/R-DDI-917841 Acidification of Tf:TfR1 containing endosome IEA Dictyostelium discoideum 43474 R-DDI-917979 https://reactome.org/PathwayBrowser/#/R-DDI-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-936895 https://reactome.org/PathwayBrowser/#/R-DDI-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Dictyostelium discoideum 43474 R-DDI-939763 https://reactome.org/PathwayBrowser/#/R-DDI-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-947591 https://reactome.org/PathwayBrowser/#/R-DDI-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Dictyostelium discoideum 43474 R-DDI-9635739 https://reactome.org/PathwayBrowser/#/R-DDI-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Dictyostelium discoideum 43474 R-DDI-9640195 https://reactome.org/PathwayBrowser/#/R-DDI-9640195 RRAGA,B hydrolyzes GTP IEA Dictyostelium discoideum 43474 R-DDI-9645598 https://reactome.org/PathwayBrowser/#/R-DDI-9645598 RRAGC,D hydrolyzes GTP IEA Dictyostelium discoideum 43474 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 43474 R-DDI-9661417 https://reactome.org/PathwayBrowser/#/R-DDI-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-9668419 https://reactome.org/PathwayBrowser/#/R-DDI-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Dictyostelium discoideum 43474 R-DDI-9684118 https://reactome.org/PathwayBrowser/#/R-DDI-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Dictyostelium discoideum 43474 R-DDI-9706399 https://reactome.org/PathwayBrowser/#/R-DDI-9706399 RHOBTB3 hydrolyzes ATP IEA Dictyostelium discoideum 43474 R-DDI-9750546 https://reactome.org/PathwayBrowser/#/R-DDI-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-9750656 https://reactome.org/PathwayBrowser/#/R-DDI-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Dictyostelium discoideum 43474 R-DDI-9753278 https://reactome.org/PathwayBrowser/#/R-DDI-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 43474 R-DDI-9753283 https://reactome.org/PathwayBrowser/#/R-DDI-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 43474 R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-9759206 https://reactome.org/PathwayBrowser/#/R-DDI-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Dictyostelium discoideum 43474 R-DDI-9759454 https://reactome.org/PathwayBrowser/#/R-DDI-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Dictyostelium discoideum 43474 R-DDI-9759461 https://reactome.org/PathwayBrowser/#/R-DDI-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Dictyostelium discoideum 43474 R-DDI-977324 https://reactome.org/PathwayBrowser/#/R-DDI-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Dictyostelium discoideum 43474 R-DDI-9837419 https://reactome.org/PathwayBrowser/#/R-DDI-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Dictyostelium discoideum 43474 R-DDI-9838004 https://reactome.org/PathwayBrowser/#/R-DDI-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Dictyostelium discoideum 43474 R-DDI-9838081 https://reactome.org/PathwayBrowser/#/R-DDI-9838081 LONP1 degrades mitochondrial matrix proteins IEA Dictyostelium discoideum 43474 R-DDI-9839105 https://reactome.org/PathwayBrowser/#/R-DDI-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Dictyostelium discoideum 43474 R-DDI-9839113 https://reactome.org/PathwayBrowser/#/R-DDI-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Dictyostelium discoideum 43474 R-DDI-9843721 https://reactome.org/PathwayBrowser/#/R-DDI-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Dictyostelium discoideum 43474 R-DDI-9853385 https://reactome.org/PathwayBrowser/#/R-DDI-9853385 PPP1CC dephosphorylates PLK1 IEA Dictyostelium discoideum 43474 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 43474 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 43474 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 43474 R-DME-110459 https://reactome.org/PathwayBrowser/#/R-DME-110459 PIP3 dephosphorylated to PIP2 by DPTEN TAS Drosophila melanogaster 43474 R-DME-110491 https://reactome.org/PathwayBrowser/#/R-DME-110491 DRheb is inhibited by the TSC1/2 complex TAS Drosophila melanogaster 43474 R-DME-111524 https://reactome.org/PathwayBrowser/#/R-DME-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Drosophila melanogaster 43474 R-DME-112033 https://reactome.org/PathwayBrowser/#/R-DME-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Drosophila melanogaster 43474 R-DME-112034 https://reactome.org/PathwayBrowser/#/R-DME-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Drosophila melanogaster 43474 R-DME-112037 https://reactome.org/PathwayBrowser/#/R-DME-112037 Inactivation of PLC beta IEA Drosophila melanogaster 43474 R-DME-1237129 https://reactome.org/PathwayBrowser/#/R-DME-1237129 Acireductone is created IEA Drosophila melanogaster 43474 R-DME-1237160 https://reactome.org/PathwayBrowser/#/R-DME-1237160 MTA is cleaved and phosphorylated IEA Drosophila melanogaster 43474 R-DME-1247935 https://reactome.org/PathwayBrowser/#/R-DME-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Drosophila melanogaster 43474 R-DME-1295632 https://reactome.org/PathwayBrowser/#/R-DME-1295632 PPA2A dephosphorylates SPRY2 IEA Drosophila melanogaster 43474 R-DME-1363274 https://reactome.org/PathwayBrowser/#/R-DME-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Drosophila melanogaster 43474 R-DME-1363276 https://reactome.org/PathwayBrowser/#/R-DME-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Drosophila melanogaster 43474 R-DME-1369065 https://reactome.org/PathwayBrowser/#/R-DME-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Drosophila melanogaster 43474 R-DME-1454916 https://reactome.org/PathwayBrowser/#/R-DME-1454916 The ABCC family mediates organic anion transport IEA Drosophila melanogaster 43474 R-DME-1454928 https://reactome.org/PathwayBrowser/#/R-DME-1454928 ABCG4 may mediate cholesterol efflux IEA Drosophila melanogaster 43474 R-DME-1467466 https://reactome.org/PathwayBrowser/#/R-DME-1467466 ABCA4 mediates atRAL transport IEA Drosophila melanogaster 43474 R-DME-1483096 https://reactome.org/PathwayBrowser/#/R-DME-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Drosophila melanogaster 43474 R-DME-1483159 https://reactome.org/PathwayBrowser/#/R-DME-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Drosophila melanogaster 43474 R-DME-1483203 https://reactome.org/PathwayBrowser/#/R-DME-1483203 PA is dephosphorylated to DAG by LPIN IEA Drosophila melanogaster 43474 R-DME-159101 https://reactome.org/PathwayBrowser/#/R-DME-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Drosophila melanogaster 43474 R-DME-164832 https://reactome.org/PathwayBrowser/#/R-DME-164832 ATPase synthesizes ATP IEA Drosophila melanogaster 43474 R-DME-164840 https://reactome.org/PathwayBrowser/#/R-DME-164840 ADP and Pi bind to ATPase IEA Drosophila melanogaster 43474 R-DME-1675795 https://reactome.org/PathwayBrowser/#/R-DME-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Drosophila melanogaster 43474 R-DME-1675824 https://reactome.org/PathwayBrowser/#/R-DME-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Drosophila melanogaster 43474 R-DME-1675836 https://reactome.org/PathwayBrowser/#/R-DME-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-1675949 https://reactome.org/PathwayBrowser/#/R-DME-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-1675988 https://reactome.org/PathwayBrowser/#/R-DME-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-1675994 https://reactome.org/PathwayBrowser/#/R-DME-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-1676065 https://reactome.org/PathwayBrowser/#/R-DME-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Drosophila melanogaster 43474 R-DME-1676105 https://reactome.org/PathwayBrowser/#/R-DME-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Drosophila melanogaster 43474 R-DME-1676114 https://reactome.org/PathwayBrowser/#/R-DME-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Drosophila melanogaster 43474 R-DME-1676124 https://reactome.org/PathwayBrowser/#/R-DME-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Drosophila melanogaster 43474 R-DME-1676133 https://reactome.org/PathwayBrowser/#/R-DME-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Drosophila melanogaster 43474 R-DME-1676141 https://reactome.org/PathwayBrowser/#/R-DME-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Drosophila melanogaster 43474 R-DME-1676149 https://reactome.org/PathwayBrowser/#/R-DME-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-1676162 https://reactome.org/PathwayBrowser/#/R-DME-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Drosophila melanogaster 43474 R-DME-1676164 https://reactome.org/PathwayBrowser/#/R-DME-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-1676177 https://reactome.org/PathwayBrowser/#/R-DME-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-1676203 https://reactome.org/PathwayBrowser/#/R-DME-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-170153 https://reactome.org/PathwayBrowser/#/R-DME-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Drosophila melanogaster 43474 R-DME-170158 https://reactome.org/PathwayBrowser/#/R-DME-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Drosophila melanogaster 43474 R-DME-170161 https://reactome.org/PathwayBrowser/#/R-DME-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Drosophila melanogaster 43474 R-DME-170666 https://reactome.org/PathwayBrowser/#/R-DME-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Drosophila melanogaster 43474 R-DME-170685 https://reactome.org/PathwayBrowser/#/R-DME-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Drosophila melanogaster 43474 R-DME-170686 https://reactome.org/PathwayBrowser/#/R-DME-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Drosophila melanogaster 43474 R-DME-174110 https://reactome.org/PathwayBrowser/#/R-DME-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Drosophila melanogaster 43474 R-DME-174367 https://reactome.org/PathwayBrowser/#/R-DME-174367 GCL ligates L-Glu to L-Cys IEA Drosophila melanogaster 43474 R-DME-174394 https://reactome.org/PathwayBrowser/#/R-DME-174394 GSS:Mg2+ dimer synthesizes GSH IEA Drosophila melanogaster 43474 R-DME-176606 https://reactome.org/PathwayBrowser/#/R-DME-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Drosophila melanogaster 43474 R-DME-177923 https://reactome.org/PathwayBrowser/#/R-DME-177923 Sustained activation of SRC kinase by SHP2 IEA Drosophila melanogaster 43474 R-DME-177924 https://reactome.org/PathwayBrowser/#/R-DME-177924 Dephosphorylation of Gab1 by SHP2 IEA Drosophila melanogaster 43474 R-DME-177935 https://reactome.org/PathwayBrowser/#/R-DME-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Drosophila melanogaster 43474 R-DME-1855154 https://reactome.org/PathwayBrowser/#/R-DME-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855165 https://reactome.org/PathwayBrowser/#/R-DME-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855166 https://reactome.org/PathwayBrowser/#/R-DME-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855174 https://reactome.org/PathwayBrowser/#/R-DME-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855180 https://reactome.org/PathwayBrowser/#/R-DME-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855198 https://reactome.org/PathwayBrowser/#/R-DME-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855202 https://reactome.org/PathwayBrowser/#/R-DME-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855205 https://reactome.org/PathwayBrowser/#/R-DME-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855208 https://reactome.org/PathwayBrowser/#/R-DME-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855210 https://reactome.org/PathwayBrowser/#/R-DME-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855211 https://reactome.org/PathwayBrowser/#/R-DME-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855213 https://reactome.org/PathwayBrowser/#/R-DME-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-1855218 https://reactome.org/PathwayBrowser/#/R-DME-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Drosophila melanogaster 43474 R-DME-1855222 https://reactome.org/PathwayBrowser/#/R-DME-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-1855232 https://reactome.org/PathwayBrowser/#/R-DME-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Drosophila melanogaster 43474 R-DME-191414 https://reactome.org/PathwayBrowser/#/R-DME-191414 MVD decarboxylates MVA5PP to IPPP IEA Drosophila melanogaster 43474 R-DME-194153 https://reactome.org/PathwayBrowser/#/R-DME-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Drosophila melanogaster 43474 R-DME-197958 https://reactome.org/PathwayBrowser/#/R-DME-197958 FPGS-2 transforms THF to THFPG IEA Drosophila melanogaster 43474 R-DME-199425 https://reactome.org/PathwayBrowser/#/R-DME-199425 PHLPP dephosphorylates S473 in AKT IEA Drosophila melanogaster 43474 R-DME-199456 https://reactome.org/PathwayBrowser/#/R-DME-199456 PTEN dephosphorylates PIP3 IEA Drosophila melanogaster 43474 R-DME-199959 https://reactome.org/PathwayBrowser/#/R-DME-199959 ERKs are inactivated by protein phosphatase 2A IEA Drosophila melanogaster 43474 R-DME-200555 https://reactome.org/PathwayBrowser/#/R-DME-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Drosophila melanogaster 43474 R-DME-200681 https://reactome.org/PathwayBrowser/#/R-DME-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Drosophila melanogaster 43474 R-DME-200682 https://reactome.org/PathwayBrowser/#/R-DME-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Drosophila melanogaster 43474 R-DME-200711 https://reactome.org/PathwayBrowser/#/R-DME-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Drosophila melanogaster 43474 R-DME-2023971 https://reactome.org/PathwayBrowser/#/R-DME-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 43474 R-DME-2023973 https://reactome.org/PathwayBrowser/#/R-DME-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 43474 R-DME-2029468 https://reactome.org/PathwayBrowser/#/R-DME-2029468 Conversion of PA into DAG by PAP-1 IEA Drosophila melanogaster 43474 R-DME-203797 https://reactome.org/PathwayBrowser/#/R-DME-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Drosophila melanogaster 43474 R-DME-204169 https://reactome.org/PathwayBrowser/#/R-DME-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Drosophila melanogaster 43474 R-DME-2046093 https://reactome.org/PathwayBrowser/#/R-DME-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Drosophila melanogaster 43474 R-DME-209055 https://reactome.org/PathwayBrowser/#/R-DME-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Drosophila melanogaster 43474 R-DME-209112 https://reactome.org/PathwayBrowser/#/R-DME-209112 Inhibition of SGG results in the dephosphorylation of the 'destruction complex' by PP2A and release of ARM IEA Drosophila melanogaster 43474 R-DME-209157 https://reactome.org/PathwayBrowser/#/R-DME-209157 Phosphorylated BSK kinase is dephosphorylated and deactivated by PUC phosphatase TAS Drosophila melanogaster 43474 R-DME-210646 https://reactome.org/PathwayBrowser/#/R-DME-210646 Phosphorylated STAT92E dimer is dephosphorylated by PTP61F isoform 1 IEA Drosophila melanogaster 43474 R-DME-210662 https://reactome.org/PathwayBrowser/#/R-DME-210662 Phosphorylated HOP is dephosphorylated by PTP61F isoform 1 TAS Drosophila melanogaster 43474 R-DME-210694 https://reactome.org/PathwayBrowser/#/R-DME-210694 Phosphorylated STAT92E dimer is dephosphorylated by PTP61F isoform 2 TAS Drosophila melanogaster 43474 R-DME-2187401 https://reactome.org/PathwayBrowser/#/R-DME-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Drosophila melanogaster 43474 R-DME-2395873 https://reactome.org/PathwayBrowser/#/R-DME-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Drosophila melanogaster 43474 R-DME-2395879 https://reactome.org/PathwayBrowser/#/R-DME-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Drosophila melanogaster 43474 R-DME-2395965 https://reactome.org/PathwayBrowser/#/R-DME-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Drosophila melanogaster 43474 R-DME-2529015 https://reactome.org/PathwayBrowser/#/R-DME-2529015 Dephosphorylation of CK2-modified condensin I IEA Drosophila melanogaster 43474 R-DME-265783 https://reactome.org/PathwayBrowser/#/R-DME-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Drosophila melanogaster 43474 R-DME-266082 https://reactome.org/PathwayBrowser/#/R-DME-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Drosophila melanogaster 43474 R-DME-2730849 https://reactome.org/PathwayBrowser/#/R-DME-2730849 Calcineurin binds and dephosphorylates NFAT IEA Drosophila melanogaster 43474 R-DME-2872498 https://reactome.org/PathwayBrowser/#/R-DME-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Drosophila melanogaster 43474 R-DME-2995388 https://reactome.org/PathwayBrowser/#/R-DME-2995388 PP2A dephosphorylates BANF1 IEA Drosophila melanogaster 43474 R-DME-3002811 https://reactome.org/PathwayBrowser/#/R-DME-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Drosophila melanogaster 43474 R-DME-3095901 https://reactome.org/PathwayBrowser/#/R-DME-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Drosophila melanogaster 43474 R-DME-3257122 https://reactome.org/PathwayBrowser/#/R-DME-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Drosophila melanogaster 43474 R-DME-3262512 https://reactome.org/PathwayBrowser/#/R-DME-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Drosophila melanogaster 43474 R-DME-3266566 https://reactome.org/PathwayBrowser/#/R-DME-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Drosophila melanogaster 43474 R-DME-3371422 https://reactome.org/PathwayBrowser/#/R-DME-3371422 ATP hydrolysis by HSP70 IEA Drosophila melanogaster 43474 R-DME-350441 https://reactome.org/PathwayBrowser/#/R-DME-350441 FLW:MYPT-75D complex dephosphorylates SQH TAS Drosophila melanogaster 43474 R-DME-350443 https://reactome.org/PathwayBrowser/#/R-DME-350443 PP1-87B:MBS complex dephosphorylates SQH TAS Drosophila melanogaster 43474 R-DME-350458 https://reactome.org/PathwayBrowser/#/R-DME-350458 RHOGAPP190 activates GTP hydrolysis by RHO1:GTP TAS Drosophila melanogaster 43474 R-DME-350475 https://reactome.org/PathwayBrowser/#/R-DME-350475 FLW:MBS complex dephosphorylates SQH TAS Drosophila melanogaster 43474 R-DME-372843 https://reactome.org/PathwayBrowser/#/R-DME-372843 SLC25A10 mediates exchange of malate and phosphate IEA Drosophila melanogaster 43474 R-DME-377643 https://reactome.org/PathwayBrowser/#/R-DME-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Drosophila melanogaster 43474 R-DME-3781011 https://reactome.org/PathwayBrowser/#/R-DME-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Drosophila melanogaster 43474 R-DME-3781018 https://reactome.org/PathwayBrowser/#/R-DME-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Drosophila melanogaster 43474 R-DME-380949 https://reactome.org/PathwayBrowser/#/R-DME-380949 AMPK is dephosphorylated IEA Drosophila melanogaster 43474 R-DME-380979 https://reactome.org/PathwayBrowser/#/R-DME-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Drosophila melanogaster 43474 R-DME-382560 https://reactome.org/PathwayBrowser/#/R-DME-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Drosophila melanogaster 43474 R-DME-382575 https://reactome.org/PathwayBrowser/#/R-DME-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Drosophila melanogaster 43474 R-DME-383190 https://reactome.org/PathwayBrowser/#/R-DME-383190 HCO3- transport through ion channel IEA Drosophila melanogaster 43474 R-DME-390329 https://reactome.org/PathwayBrowser/#/R-DME-390329 Dephosphorylation of AKT by PP2A IEA Drosophila melanogaster 43474 R-DME-4084976 https://reactome.org/PathwayBrowser/#/R-DME-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Drosophila melanogaster 43474 R-DME-4084989 https://reactome.org/PathwayBrowser/#/R-DME-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Drosophila melanogaster 43474 R-DME-4093339 https://reactome.org/PathwayBrowser/#/R-DME-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Drosophila melanogaster 43474 R-DME-416639 https://reactome.org/PathwayBrowser/#/R-DME-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Drosophila melanogaster 43474 R-DME-416985 https://reactome.org/PathwayBrowser/#/R-DME-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Drosophila melanogaster 43474 R-DME-421007 https://reactome.org/PathwayBrowser/#/R-DME-421007 Endocytosis of Ca impermeable AMPA receptors IEA Drosophila melanogaster 43474 R-DME-421831 https://reactome.org/PathwayBrowser/#/R-DME-421831 trans-Golgi Network Coat Assembly IEA Drosophila melanogaster 43474 R-DME-421835 https://reactome.org/PathwayBrowser/#/R-DME-421835 trans-Golgi Network Vesicle Scission IEA Drosophila melanogaster 43474 R-DME-427605 https://reactome.org/PathwayBrowser/#/R-DME-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 43474 R-DME-428609 https://reactome.org/PathwayBrowser/#/R-DME-428609 Type I Na+-coupled phosphate co-transport IEA Drosophila melanogaster 43474 R-DME-428690 https://reactome.org/PathwayBrowser/#/R-DME-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Drosophila melanogaster 43474 R-DME-428696 https://reactome.org/PathwayBrowser/#/R-DME-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Drosophila melanogaster 43474 R-DME-429157 https://reactome.org/PathwayBrowser/#/R-DME-429157 ABCC4 accumulation of dense granule contents IEA Drosophila melanogaster 43474 R-DME-429730 https://reactome.org/PathwayBrowser/#/R-DME-429730 PPM1L dephosphorylates multiphospho-CERT1-2 IEA Drosophila melanogaster 43474 R-DME-432427 https://reactome.org/PathwayBrowser/#/R-DME-432427 PP1 dephosphorylates phosphorylated TIM TAS Drosophila melanogaster 43474 R-DME-432527 https://reactome.org/PathwayBrowser/#/R-DME-432527 Nuclear PP2A dephosphorylates phosphorylated PER TAS Drosophila melanogaster 43474 R-DME-432537 https://reactome.org/PathwayBrowser/#/R-DME-432537 PP2A dephosphorylates phosphorylated CLK TAS Drosophila melanogaster 43474 R-DME-432556 https://reactome.org/PathwayBrowser/#/R-DME-432556 Cytosolic PP2A dephosphorylates phosphorylated PER complexed with DCO TAS Drosophila melanogaster 43474 R-DME-432706 https://reactome.org/PathwayBrowser/#/R-DME-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Drosophila melanogaster 43474 R-DME-432707 https://reactome.org/PathwayBrowser/#/R-DME-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Drosophila melanogaster 43474 R-DME-4419948 https://reactome.org/PathwayBrowser/#/R-DME-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Drosophila melanogaster 43474 R-DME-445699 https://reactome.org/PathwayBrowser/#/R-DME-445699 ATP Hydrolysis By Myosin IEA Drosophila melanogaster 43474 R-DME-449937 https://reactome.org/PathwayBrowser/#/R-DME-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Drosophila melanogaster 43474 R-DME-4551451 https://reactome.org/PathwayBrowser/#/R-DME-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Drosophila melanogaster 43474 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 43474 R-DME-504054 https://reactome.org/PathwayBrowser/#/R-DME-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Drosophila melanogaster 43474 R-DME-508040 https://reactome.org/PathwayBrowser/#/R-DME-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Drosophila melanogaster 43474 R-DME-508308 https://reactome.org/PathwayBrowser/#/R-DME-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Drosophila melanogaster 43474 R-DME-5221130 https://reactome.org/PathwayBrowser/#/R-DME-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Drosophila melanogaster 43474 R-DME-5251989 https://reactome.org/PathwayBrowser/#/R-DME-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Drosophila melanogaster 43474 R-DME-538822 https://reactome.org/PathwayBrowser/#/R-DME-538822 Cytosolic PP2A dephosphorylates phosphorylated PER complexed with TIM and DCO TAS Drosophila melanogaster 43474 R-DME-538832 https://reactome.org/PathwayBrowser/#/R-DME-538832 PP1 dephosphorylates phosphorylated TIM in the complex with PER and DCO TAS Drosophila melanogaster 43474 R-DME-5419271 https://reactome.org/PathwayBrowser/#/R-DME-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Drosophila melanogaster 43474 R-DME-5419273 https://reactome.org/PathwayBrowser/#/R-DME-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Drosophila melanogaster 43474 R-DME-555065 https://reactome.org/PathwayBrowser/#/R-DME-555065 Formation of clathrin coated vesicle IEA Drosophila melanogaster 43474 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 43474 R-DME-5623513 https://reactome.org/PathwayBrowser/#/R-DME-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Drosophila melanogaster 43474 R-DME-5672957 https://reactome.org/PathwayBrowser/#/R-DME-5672957 PP2A dephosphorylates KSR1 IEA Drosophila melanogaster 43474 R-DME-5672961 https://reactome.org/PathwayBrowser/#/R-DME-5672961 PP2A dephosphorylates inactive RAFs IEA Drosophila melanogaster 43474 R-DME-5675376 https://reactome.org/PathwayBrowser/#/R-DME-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Drosophila melanogaster 43474 R-DME-5675431 https://reactome.org/PathwayBrowser/#/R-DME-5675431 PP2A dephosphorylates RAF1 IEA Drosophila melanogaster 43474 R-DME-5675433 https://reactome.org/PathwayBrowser/#/R-DME-5675433 PP5 dephosphorylates RAF1 S338 IEA Drosophila melanogaster 43474 R-DME-5678863 https://reactome.org/PathwayBrowser/#/R-DME-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Drosophila melanogaster 43474 R-DME-5679041 https://reactome.org/PathwayBrowser/#/R-DME-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 43474 R-DME-5682285 https://reactome.org/PathwayBrowser/#/R-DME-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Drosophila melanogaster 43474 R-DME-5683714 https://reactome.org/PathwayBrowser/#/R-DME-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Drosophila melanogaster 43474 R-DME-5683925 https://reactome.org/PathwayBrowser/#/R-DME-5683925 ULK1 is dephosphorylated IEA Drosophila melanogaster 43474 R-DME-5683967 https://reactome.org/PathwayBrowser/#/R-DME-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Drosophila melanogaster 43474 R-DME-5687758 https://reactome.org/PathwayBrowser/#/R-DME-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Drosophila melanogaster 43474 R-DME-5690996 https://reactome.org/PathwayBrowser/#/R-DME-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Drosophila melanogaster 43474 R-DME-5692462 https://reactome.org/PathwayBrowser/#/R-DME-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Drosophila melanogaster 43474 R-DME-5694126 https://reactome.org/PathwayBrowser/#/R-DME-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Drosophila melanogaster 43474 R-DME-5694425 https://reactome.org/PathwayBrowser/#/R-DME-5694425 NSF ATPase activity dissociates cis-SNARE IEA Drosophila melanogaster 43474 R-DME-5694527 https://reactome.org/PathwayBrowser/#/R-DME-5694527 Loss of SAR1B GTPase IEA Drosophila melanogaster 43474 R-DME-5696408 https://reactome.org/PathwayBrowser/#/R-DME-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Drosophila melanogaster 43474 R-DME-5696415 https://reactome.org/PathwayBrowser/#/R-DME-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Drosophila melanogaster 43474 R-DME-5696839 https://reactome.org/PathwayBrowser/#/R-DME-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Drosophila melanogaster 43474 R-DME-6782131 https://reactome.org/PathwayBrowser/#/R-DME-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Drosophila melanogaster 43474 R-DME-6788295 https://reactome.org/PathwayBrowser/#/R-DME-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Drosophila melanogaster 43474 R-DME-6801342 https://reactome.org/PathwayBrowser/#/R-DME-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Drosophila melanogaster 43474 R-DME-6801456 https://reactome.org/PathwayBrowser/#/R-DME-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Drosophila melanogaster 43474 R-DME-6806967 https://reactome.org/PathwayBrowser/#/R-DME-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Drosophila melanogaster 43474 R-DME-6809320 https://reactome.org/PathwayBrowser/#/R-DME-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-6809325 https://reactome.org/PathwayBrowser/#/R-DME-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Drosophila melanogaster 43474 R-DME-6809720 https://reactome.org/PathwayBrowser/#/R-DME-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Drosophila melanogaster 43474 R-DME-6809777 https://reactome.org/PathwayBrowser/#/R-DME-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Drosophila melanogaster 43474 R-DME-6809778 https://reactome.org/PathwayBrowser/#/R-DME-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Drosophila melanogaster 43474 R-DME-6810410 https://reactome.org/PathwayBrowser/#/R-DME-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Drosophila melanogaster 43474 R-DME-6811422 https://reactome.org/PathwayBrowser/#/R-DME-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Drosophila melanogaster 43474 R-DME-6811504 https://reactome.org/PathwayBrowser/#/R-DME-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Drosophila melanogaster 43474 R-DME-6814120 https://reactome.org/PathwayBrowser/#/R-DME-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Drosophila melanogaster 43474 R-DME-69199 https://reactome.org/PathwayBrowser/#/R-DME-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Drosophila melanogaster 43474 R-DME-70262 https://reactome.org/PathwayBrowser/#/R-DME-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Drosophila melanogaster 43474 R-DME-70449 https://reactome.org/PathwayBrowser/#/R-DME-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Drosophila melanogaster 43474 R-DME-70479 https://reactome.org/PathwayBrowser/#/R-DME-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Drosophila melanogaster 43474 R-DME-70482 https://reactome.org/PathwayBrowser/#/R-DME-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Drosophila melanogaster 43474 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 43474 R-DME-70606 https://reactome.org/PathwayBrowser/#/R-DME-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Drosophila melanogaster 43474 R-DME-70773 https://reactome.org/PathwayBrowser/#/R-DME-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Drosophila melanogaster 43474 R-DME-70997 https://reactome.org/PathwayBrowser/#/R-DME-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Drosophila melanogaster 43474 R-DME-71732 https://reactome.org/PathwayBrowser/#/R-DME-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Drosophila melanogaster 43474 R-DME-71775 https://reactome.org/PathwayBrowser/#/R-DME-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Drosophila melanogaster 43474 R-DME-71825 https://reactome.org/PathwayBrowser/#/R-DME-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Drosophila melanogaster 43474 R-DME-72621 https://reactome.org/PathwayBrowser/#/R-DME-72621 Ribosomal scanning IEA Drosophila melanogaster 43474 R-DME-72671 https://reactome.org/PathwayBrowser/#/R-DME-72671 eIF5B:GTP is hydrolyzed and released IEA Drosophila melanogaster 43474 R-DME-73573 https://reactome.org/PathwayBrowser/#/R-DME-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Drosophila melanogaster 43474 R-DME-73577 https://reactome.org/PathwayBrowser/#/R-DME-73577 CAD hexamer transforms L-Gln to CAP IEA Drosophila melanogaster 43474 R-DME-73647 https://reactome.org/PathwayBrowser/#/R-DME-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Drosophila melanogaster 43474 R-DME-73805 https://reactome.org/PathwayBrowser/#/R-DME-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Drosophila melanogaster 43474 R-DME-73810 https://reactome.org/PathwayBrowser/#/R-DME-73810 FGAM + ATP => AIR + ADP + Pi IEA Drosophila melanogaster 43474 R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 43474 R-DME-73814 https://reactome.org/PathwayBrowser/#/R-DME-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Drosophila melanogaster 43474 R-DME-74242 https://reactome.org/PathwayBrowser/#/R-DME-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Drosophila melanogaster 43474 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 43474 R-DME-74249 https://reactome.org/PathwayBrowser/#/R-DME-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Drosophila melanogaster 43474 R-DME-74372 https://reactome.org/PathwayBrowser/#/R-DME-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Drosophila melanogaster 43474 R-DME-74376 https://reactome.org/PathwayBrowser/#/R-DME-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Drosophila melanogaster 43474 R-DME-74733 https://reactome.org/PathwayBrowser/#/R-DME-74733 Insulin receptor de-phosphorylation IEA Drosophila melanogaster 43474 R-DME-75848 https://reactome.org/PathwayBrowser/#/R-DME-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Drosophila melanogaster 43474 R-DME-75851 https://reactome.org/PathwayBrowser/#/R-DME-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 43474 R-DME-75899 https://reactome.org/PathwayBrowser/#/R-DME-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Drosophila melanogaster 43474 R-DME-75949 https://reactome.org/PathwayBrowser/#/R-DME-75949 RNA Polymerase II Promoter Opening: First Transition IEA Drosophila melanogaster 43474 R-DME-77078 https://reactome.org/PathwayBrowser/#/R-DME-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Drosophila melanogaster 43474 R-DME-8849082 https://reactome.org/PathwayBrowser/#/R-DME-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Drosophila melanogaster 43474 R-DME-8849969 https://reactome.org/PathwayBrowser/#/R-DME-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Drosophila melanogaster 43474 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 43474 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 43474 R-DME-8854173 https://reactome.org/PathwayBrowser/#/R-DME-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Drosophila melanogaster 43474 R-DME-8854255 https://reactome.org/PathwayBrowser/#/R-DME-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 43474 R-DME-8854329 https://reactome.org/PathwayBrowser/#/R-DME-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 43474 R-DME-8854604 https://reactome.org/PathwayBrowser/#/R-DME-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Drosophila melanogaster 43474 R-DME-8864125 https://reactome.org/PathwayBrowser/#/R-DME-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Drosophila melanogaster 43474 R-DME-8867047 https://reactome.org/PathwayBrowser/#/R-DME-8867047 PTPN3 dephosphorylates EPS15 IEA Drosophila melanogaster 43474 R-DME-8867658 https://reactome.org/PathwayBrowser/#/R-DME-8867658 PTPN3 dephosphorylates MAPK12 IEA Drosophila melanogaster 43474 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster 43474 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster 43474 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster 43474 R-DME-8876889 https://reactome.org/PathwayBrowser/#/R-DME-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 43474 R-DME-8878787 https://reactome.org/PathwayBrowser/#/R-DME-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Drosophila melanogaster 43474 R-DME-8940070 https://reactome.org/PathwayBrowser/#/R-DME-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Drosophila melanogaster 43474 R-DME-8940074 https://reactome.org/PathwayBrowser/#/R-DME-8940074 NT5E:Zn2+ hydrolyses NMN IEA Drosophila melanogaster 43474 R-DME-8952137 https://reactome.org/PathwayBrowser/#/R-DME-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Drosophila melanogaster 43474 R-DME-8953499 https://reactome.org/PathwayBrowser/#/R-DME-8953499 IMPAD1 hydrolyses PAP to AMP IEA Drosophila melanogaster 43474 R-DME-8959510 https://reactome.org/PathwayBrowser/#/R-DME-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Drosophila melanogaster 43474 R-DME-8981637 https://reactome.org/PathwayBrowser/#/R-DME-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Drosophila melanogaster 43474 R-DME-8982020 https://reactome.org/PathwayBrowser/#/R-DME-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Drosophila melanogaster 43474 R-DME-8982025 https://reactome.org/PathwayBrowser/#/R-DME-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Drosophila melanogaster 43474 R-DME-9013022 https://reactome.org/PathwayBrowser/#/R-DME-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Drosophila melanogaster 43474 R-DME-9013144 https://reactome.org/PathwayBrowser/#/R-DME-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Drosophila melanogaster 43474 R-DME-9013161 https://reactome.org/PathwayBrowser/#/R-DME-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Drosophila melanogaster 43474 R-DME-9013437 https://reactome.org/PathwayBrowser/#/R-DME-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Drosophila melanogaster 43474 R-DME-9014295 https://reactome.org/PathwayBrowser/#/R-DME-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Drosophila melanogaster 43474 R-DME-9014434 https://reactome.org/PathwayBrowser/#/R-DME-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Drosophila melanogaster 43474 R-DME-9017488 https://reactome.org/PathwayBrowser/#/R-DME-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Drosophila melanogaster 43474 R-DME-9018745 https://reactome.org/PathwayBrowser/#/R-DME-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Drosophila melanogaster 43474 R-DME-9018806 https://reactome.org/PathwayBrowser/#/R-DME-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Drosophila melanogaster 43474 R-DME-9018814 https://reactome.org/PathwayBrowser/#/R-DME-9018814 RHOT1 hydrolyzes GTP IEA Drosophila melanogaster 43474 R-DME-9018826 https://reactome.org/PathwayBrowser/#/R-DME-9018826 RHOT2 hydrolyzes GTP IEA Drosophila melanogaster 43474 R-DME-9038161 https://reactome.org/PathwayBrowser/#/R-DME-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Drosophila melanogaster 43474 R-DME-917693 https://reactome.org/PathwayBrowser/#/R-DME-917693 ESCRT Disassembly IEA Drosophila melanogaster 43474 R-DME-917841 https://reactome.org/PathwayBrowser/#/R-DME-917841 Acidification of Tf:TfR1 containing endosome IEA Drosophila melanogaster 43474 R-DME-917979 https://reactome.org/PathwayBrowser/#/R-DME-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Drosophila melanogaster 43474 R-DME-936883 https://reactome.org/PathwayBrowser/#/R-DME-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Drosophila melanogaster 43474 R-DME-936895 https://reactome.org/PathwayBrowser/#/R-DME-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Drosophila melanogaster 43474 R-DME-939763 https://reactome.org/PathwayBrowser/#/R-DME-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Drosophila melanogaster 43474 R-DME-947591 https://reactome.org/PathwayBrowser/#/R-DME-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Drosophila melanogaster 43474 R-DME-9624893 https://reactome.org/PathwayBrowser/#/R-DME-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Drosophila melanogaster 43474 R-DME-9635739 https://reactome.org/PathwayBrowser/#/R-DME-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Drosophila melanogaster 43474 R-DME-9640195 https://reactome.org/PathwayBrowser/#/R-DME-9640195 RRAGA,B hydrolyzes GTP IEA Drosophila melanogaster 43474 R-DME-9645598 https://reactome.org/PathwayBrowser/#/R-DME-9645598 RRAGC,D hydrolyzes GTP IEA Drosophila melanogaster 43474 R-DME-9661417 https://reactome.org/PathwayBrowser/#/R-DME-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 43474 R-DME-9674816 https://reactome.org/PathwayBrowser/#/R-DME-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Drosophila melanogaster 43474 R-DME-9684118 https://reactome.org/PathwayBrowser/#/R-DME-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Drosophila melanogaster 43474 R-DME-9693282 https://reactome.org/PathwayBrowser/#/R-DME-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Drosophila melanogaster 43474 R-DME-9706399 https://reactome.org/PathwayBrowser/#/R-DME-9706399 RHOBTB3 hydrolyzes ATP IEA Drosophila melanogaster 43474 R-DME-9750546 https://reactome.org/PathwayBrowser/#/R-DME-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Drosophila melanogaster 43474 R-DME-9750656 https://reactome.org/PathwayBrowser/#/R-DME-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Drosophila melanogaster 43474 R-DME-9753278 https://reactome.org/PathwayBrowser/#/R-DME-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 43474 R-DME-9753283 https://reactome.org/PathwayBrowser/#/R-DME-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 43474 R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 43474 R-DME-9770141 https://reactome.org/PathwayBrowser/#/R-DME-9770141 Formation of the Spliceosomal C* complex IEA Drosophila melanogaster 43474 R-DME-977324 https://reactome.org/PathwayBrowser/#/R-DME-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Drosophila melanogaster 43474 R-DME-9838004 https://reactome.org/PathwayBrowser/#/R-DME-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Drosophila melanogaster 43474 R-DME-9838081 https://reactome.org/PathwayBrowser/#/R-DME-9838081 LONP1 degrades mitochondrial matrix proteins IEA Drosophila melanogaster 43474 R-DME-9838289 https://reactome.org/PathwayBrowser/#/R-DME-9838289 CLPXP degrades mitochondrial matrix proteins IEA Drosophila melanogaster 43474 R-DME-9839059 https://reactome.org/PathwayBrowser/#/R-DME-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Drosophila melanogaster 43474 R-DME-9839105 https://reactome.org/PathwayBrowser/#/R-DME-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Drosophila melanogaster 43474 R-DME-9839113 https://reactome.org/PathwayBrowser/#/R-DME-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Drosophila melanogaster 43474 R-DME-9843721 https://reactome.org/PathwayBrowser/#/R-DME-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Drosophila melanogaster 43474 R-DME-9853385 https://reactome.org/PathwayBrowser/#/R-DME-9853385 PPP1CC dephosphorylates PLK1 IEA Drosophila melanogaster 43474 R-DME-9861725 https://reactome.org/PathwayBrowser/#/R-DME-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Drosophila melanogaster 43474 R-DME-997326 https://reactome.org/PathwayBrowser/#/R-DME-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Drosophila melanogaster 43474 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 43474 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 43474 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 43474 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 43474 R-DRE-109415 https://reactome.org/PathwayBrowser/#/R-DRE-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Danio rerio 43474 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 43474 R-DRE-111215 https://reactome.org/PathwayBrowser/#/R-DRE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Danio rerio 43474 R-DRE-111524 https://reactome.org/PathwayBrowser/#/R-DRE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Danio rerio 43474 R-DRE-112033 https://reactome.org/PathwayBrowser/#/R-DRE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Danio rerio 43474 R-DRE-112034 https://reactome.org/PathwayBrowser/#/R-DRE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Danio rerio 43474 R-DRE-113503 https://reactome.org/PathwayBrowser/#/R-DRE-113503 PP2A mediated localization of RB1 protein in chromatin IEA Danio rerio 43474 R-DRE-1169192 https://reactome.org/PathwayBrowser/#/R-DRE-1169192 PTP1B dephosphorylates GHR IEA Danio rerio 43474 R-DRE-1237129 https://reactome.org/PathwayBrowser/#/R-DRE-1237129 Acireductone is created IEA Danio rerio 43474 R-DRE-1237160 https://reactome.org/PathwayBrowser/#/R-DRE-1237160 MTA is cleaved and phosphorylated IEA Danio rerio 43474 R-DRE-1247935 https://reactome.org/PathwayBrowser/#/R-DRE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Danio rerio 43474 R-DRE-1295632 https://reactome.org/PathwayBrowser/#/R-DRE-1295632 PPA2A dephosphorylates SPRY2 IEA Danio rerio 43474 R-DRE-1363274 https://reactome.org/PathwayBrowser/#/R-DRE-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Danio rerio 43474 R-DRE-1454916 https://reactome.org/PathwayBrowser/#/R-DRE-1454916 The ABCC family mediates organic anion transport IEA Danio rerio 43474 R-DRE-1454928 https://reactome.org/PathwayBrowser/#/R-DRE-1454928 ABCG4 may mediate cholesterol efflux IEA Danio rerio 43474 R-DRE-1483096 https://reactome.org/PathwayBrowser/#/R-DRE-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Danio rerio 43474 R-DRE-1483159 https://reactome.org/PathwayBrowser/#/R-DRE-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Danio rerio 43474 R-DRE-1483203 https://reactome.org/PathwayBrowser/#/R-DRE-1483203 PA is dephosphorylated to DAG by LPIN IEA Danio rerio 43474 R-DRE-164832 https://reactome.org/PathwayBrowser/#/R-DRE-164832 ATPase synthesizes ATP IEA Danio rerio 43474 R-DRE-164840 https://reactome.org/PathwayBrowser/#/R-DRE-164840 ADP and Pi bind to ATPase IEA Danio rerio 43474 R-DRE-1675795 https://reactome.org/PathwayBrowser/#/R-DRE-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Danio rerio 43474 R-DRE-1675949 https://reactome.org/PathwayBrowser/#/R-DRE-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Danio rerio 43474 R-DRE-1675994 https://reactome.org/PathwayBrowser/#/R-DRE-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Danio rerio 43474 R-DRE-1676065 https://reactome.org/PathwayBrowser/#/R-DRE-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Danio rerio 43474 R-DRE-1676105 https://reactome.org/PathwayBrowser/#/R-DRE-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Danio rerio 43474 R-DRE-1676114 https://reactome.org/PathwayBrowser/#/R-DRE-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Danio rerio 43474 R-DRE-1676124 https://reactome.org/PathwayBrowser/#/R-DRE-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Danio rerio 43474 R-DRE-1676133 https://reactome.org/PathwayBrowser/#/R-DRE-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Danio rerio 43474 R-DRE-1676141 https://reactome.org/PathwayBrowser/#/R-DRE-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Danio rerio 43474 R-DRE-1676149 https://reactome.org/PathwayBrowser/#/R-DRE-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Danio rerio 43474 R-DRE-1676162 https://reactome.org/PathwayBrowser/#/R-DRE-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Danio rerio 43474 R-DRE-1676164 https://reactome.org/PathwayBrowser/#/R-DRE-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Danio rerio 43474 R-DRE-1676203 https://reactome.org/PathwayBrowser/#/R-DRE-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Danio rerio 43474 R-DRE-1676204 https://reactome.org/PathwayBrowser/#/R-DRE-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Danio rerio 43474 R-DRE-170666 https://reactome.org/PathwayBrowser/#/R-DRE-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Danio rerio 43474 R-DRE-170685 https://reactome.org/PathwayBrowser/#/R-DRE-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Danio rerio 43474 R-DRE-170686 https://reactome.org/PathwayBrowser/#/R-DRE-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Danio rerio 43474 R-DRE-174391 https://reactome.org/PathwayBrowser/#/R-DRE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Danio rerio 43474 R-DRE-174394 https://reactome.org/PathwayBrowser/#/R-DRE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Danio rerio 43474 R-DRE-1855154 https://reactome.org/PathwayBrowser/#/R-DRE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 43474 R-DRE-1855159 https://reactome.org/PathwayBrowser/#/R-DRE-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Danio rerio 43474 R-DRE-1855163 https://reactome.org/PathwayBrowser/#/R-DRE-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Danio rerio 43474 R-DRE-1855165 https://reactome.org/PathwayBrowser/#/R-DRE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 43474 R-DRE-1855166 https://reactome.org/PathwayBrowser/#/R-DRE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Danio rerio 43474 R-DRE-1855171 https://reactome.org/PathwayBrowser/#/R-DRE-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Danio rerio 43474 R-DRE-1855180 https://reactome.org/PathwayBrowser/#/R-DRE-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Danio rerio 43474 R-DRE-1855198 https://reactome.org/PathwayBrowser/#/R-DRE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 43474 R-DRE-1855200 https://reactome.org/PathwayBrowser/#/R-DRE-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Danio rerio 43474 R-DRE-1855202 https://reactome.org/PathwayBrowser/#/R-DRE-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Danio rerio 43474 R-DRE-1855205 https://reactome.org/PathwayBrowser/#/R-DRE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Danio rerio 43474 R-DRE-1855210 https://reactome.org/PathwayBrowser/#/R-DRE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 43474 R-DRE-1855211 https://reactome.org/PathwayBrowser/#/R-DRE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 43474 R-DRE-1855218 https://reactome.org/PathwayBrowser/#/R-DRE-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Danio rerio 43474 R-DRE-1855219 https://reactome.org/PathwayBrowser/#/R-DRE-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Danio rerio 43474 R-DRE-1855222 https://reactome.org/PathwayBrowser/#/R-DRE-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Danio rerio 43474 R-DRE-1855225 https://reactome.org/PathwayBrowser/#/R-DRE-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Danio rerio 43474 R-DRE-191414 https://reactome.org/PathwayBrowser/#/R-DRE-191414 MVD decarboxylates MVA5PP to IPPP IEA Danio rerio 43474 R-DRE-196950 https://reactome.org/PathwayBrowser/#/R-DRE-196950 2xTRAP hydrolyzes FMN to RIB IEA Danio rerio 43474 R-DRE-197958 https://reactome.org/PathwayBrowser/#/R-DRE-197958 FPGS-2 transforms THF to THFPG IEA Danio rerio 43474 R-DRE-198513 https://reactome.org/PathwayBrowser/#/R-DRE-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Danio rerio 43474 R-DRE-199456 https://reactome.org/PathwayBrowser/#/R-DRE-199456 PTEN dephosphorylates PIP3 IEA Danio rerio 43474 R-DRE-199959 https://reactome.org/PathwayBrowser/#/R-DRE-199959 ERKs are inactivated by protein phosphatase 2A IEA Danio rerio 43474 R-DRE-200681 https://reactome.org/PathwayBrowser/#/R-DRE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Danio rerio 43474 R-DRE-200682 https://reactome.org/PathwayBrowser/#/R-DRE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Danio rerio 43474 R-DRE-200711 https://reactome.org/PathwayBrowser/#/R-DRE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Danio rerio 43474 R-DRE-2023971 https://reactome.org/PathwayBrowser/#/R-DRE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 43474 R-DRE-2023973 https://reactome.org/PathwayBrowser/#/R-DRE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 43474 R-DRE-203797 https://reactome.org/PathwayBrowser/#/R-DRE-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Danio rerio 43474 R-DRE-2130641 https://reactome.org/PathwayBrowser/#/R-DRE-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Danio rerio 43474 R-DRE-216723 https://reactome.org/PathwayBrowser/#/R-DRE-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Danio rerio 43474 R-DRE-216757 https://reactome.org/PathwayBrowser/#/R-DRE-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Danio rerio 43474 R-DRE-2395873 https://reactome.org/PathwayBrowser/#/R-DRE-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Danio rerio 43474 R-DRE-2395879 https://reactome.org/PathwayBrowser/#/R-DRE-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Danio rerio 43474 R-DRE-2395965 https://reactome.org/PathwayBrowser/#/R-DRE-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Danio rerio 43474 R-DRE-2408551 https://reactome.org/PathwayBrowser/#/R-DRE-2408551 SeMet is converted to AdoSeMet by MAT IEA Danio rerio 43474 R-DRE-2509793 https://reactome.org/PathwayBrowser/#/R-DRE-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Danio rerio 43474 R-DRE-2509816 https://reactome.org/PathwayBrowser/#/R-DRE-2509816 NUDT16 hydrolyses IDP to IMP IEA Danio rerio 43474 R-DRE-266082 https://reactome.org/PathwayBrowser/#/R-DRE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Danio rerio 43474 R-DRE-2995388 https://reactome.org/PathwayBrowser/#/R-DRE-2995388 PP2A dephosphorylates BANF1 IEA Danio rerio 43474 R-DRE-3002811 https://reactome.org/PathwayBrowser/#/R-DRE-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Danio rerio 43474 R-DRE-3257122 https://reactome.org/PathwayBrowser/#/R-DRE-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Danio rerio 43474 R-DRE-3262512 https://reactome.org/PathwayBrowser/#/R-DRE-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Danio rerio 43474 R-DRE-3371422 https://reactome.org/PathwayBrowser/#/R-DRE-3371422 ATP hydrolysis by HSP70 IEA Danio rerio 43474 R-DRE-372843 https://reactome.org/PathwayBrowser/#/R-DRE-372843 SLC25A10 mediates exchange of malate and phosphate IEA Danio rerio 43474 R-DRE-3781018 https://reactome.org/PathwayBrowser/#/R-DRE-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Danio rerio 43474 R-DRE-380979 https://reactome.org/PathwayBrowser/#/R-DRE-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Danio rerio 43474 R-DRE-382560 https://reactome.org/PathwayBrowser/#/R-DRE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Danio rerio 43474 R-DRE-382575 https://reactome.org/PathwayBrowser/#/R-DRE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Danio rerio 43474 R-DRE-383190 https://reactome.org/PathwayBrowser/#/R-DRE-383190 HCO3- transport through ion channel IEA Danio rerio 43474 R-DRE-4084976 https://reactome.org/PathwayBrowser/#/R-DRE-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Danio rerio 43474 R-DRE-4084989 https://reactome.org/PathwayBrowser/#/R-DRE-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Danio rerio 43474 R-DRE-4088141 https://reactome.org/PathwayBrowser/#/R-DRE-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Danio rerio 43474 R-DRE-4093339 https://reactome.org/PathwayBrowser/#/R-DRE-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Danio rerio 43474 R-DRE-416546 https://reactome.org/PathwayBrowser/#/R-DRE-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Danio rerio 43474 R-DRE-416559 https://reactome.org/PathwayBrowser/#/R-DRE-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Danio rerio 43474 R-DRE-427605 https://reactome.org/PathwayBrowser/#/R-DRE-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Danio rerio 43474 R-DRE-427656 https://reactome.org/PathwayBrowser/#/R-DRE-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Danio rerio 43474 R-DRE-428696 https://reactome.org/PathwayBrowser/#/R-DRE-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Danio rerio 43474 R-DRE-429157 https://reactome.org/PathwayBrowser/#/R-DRE-429157 ABCC4 accumulation of dense granule contents IEA Danio rerio 43474 R-DRE-429730 https://reactome.org/PathwayBrowser/#/R-DRE-429730 PPM1L dephosphorylates multiphospho-CERT1-2 IEA Danio rerio 43474 R-DRE-432707 https://reactome.org/PathwayBrowser/#/R-DRE-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Danio rerio 43474 R-DRE-446200 https://reactome.org/PathwayBrowser/#/R-DRE-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Danio rerio 43474 R-DRE-449937 https://reactome.org/PathwayBrowser/#/R-DRE-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Danio rerio 43474 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 43474 R-DRE-504054 https://reactome.org/PathwayBrowser/#/R-DRE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Danio rerio 43474 R-DRE-5223317 https://reactome.org/PathwayBrowser/#/R-DRE-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Danio rerio 43474 R-DRE-5251955 https://reactome.org/PathwayBrowser/#/R-DRE-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Danio rerio 43474 R-DRE-5251959 https://reactome.org/PathwayBrowser/#/R-DRE-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Danio rerio 43474 R-DRE-5603114 https://reactome.org/PathwayBrowser/#/R-DRE-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Danio rerio 43474 R-DRE-5623513 https://reactome.org/PathwayBrowser/#/R-DRE-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Danio rerio 43474 R-DRE-5628905 https://reactome.org/PathwayBrowser/#/R-DRE-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Danio rerio 43474 R-DRE-5649705 https://reactome.org/PathwayBrowser/#/R-DRE-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Danio rerio 43474 R-DRE-5665809 https://reactome.org/PathwayBrowser/#/R-DRE-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Danio rerio 43474 R-DRE-5675373 https://reactome.org/PathwayBrowser/#/R-DRE-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Danio rerio 43474 R-DRE-5675376 https://reactome.org/PathwayBrowser/#/R-DRE-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Danio rerio 43474 R-DRE-5678863 https://reactome.org/PathwayBrowser/#/R-DRE-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Danio rerio 43474 R-DRE-5679041 https://reactome.org/PathwayBrowser/#/R-DRE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Danio rerio 43474 R-DRE-5687758 https://reactome.org/PathwayBrowser/#/R-DRE-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Danio rerio 43474 R-DRE-5690996 https://reactome.org/PathwayBrowser/#/R-DRE-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Danio rerio 43474 R-DRE-5692480 https://reactome.org/PathwayBrowser/#/R-DRE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Danio rerio 43474 R-DRE-5692754 https://reactome.org/PathwayBrowser/#/R-DRE-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Danio rerio 43474 R-DRE-5694425 https://reactome.org/PathwayBrowser/#/R-DRE-5694425 NSF ATPase activity dissociates cis-SNARE IEA Danio rerio 43474 R-DRE-5696408 https://reactome.org/PathwayBrowser/#/R-DRE-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Danio rerio 43474 R-DRE-5696415 https://reactome.org/PathwayBrowser/#/R-DRE-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Danio rerio 43474 R-DRE-5696839 https://reactome.org/PathwayBrowser/#/R-DRE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Danio rerio 43474 R-DRE-6782131 https://reactome.org/PathwayBrowser/#/R-DRE-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Danio rerio 43474 R-DRE-6788295 https://reactome.org/PathwayBrowser/#/R-DRE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Danio rerio 43474 R-DRE-6788912 https://reactome.org/PathwayBrowser/#/R-DRE-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Danio rerio 43474 R-DRE-6801342 https://reactome.org/PathwayBrowser/#/R-DRE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio 43474 R-DRE-6801456 https://reactome.org/PathwayBrowser/#/R-DRE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Danio rerio 43474 R-DRE-6803545 https://reactome.org/PathwayBrowser/#/R-DRE-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Danio rerio 43474 R-DRE-6806967 https://reactome.org/PathwayBrowser/#/R-DRE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Danio rerio 43474 R-DRE-6809320 https://reactome.org/PathwayBrowser/#/R-DRE-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Danio rerio 43474 R-DRE-6809325 https://reactome.org/PathwayBrowser/#/R-DRE-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Danio rerio 43474 R-DRE-6809720 https://reactome.org/PathwayBrowser/#/R-DRE-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Danio rerio 43474 R-DRE-6810410 https://reactome.org/PathwayBrowser/#/R-DRE-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Danio rerio 43474 R-DRE-6811504 https://reactome.org/PathwayBrowser/#/R-DRE-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Danio rerio 43474 R-DRE-6814120 https://reactome.org/PathwayBrowser/#/R-DRE-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Danio rerio 43474 R-DRE-70449 https://reactome.org/PathwayBrowser/#/R-DRE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Danio rerio 43474 R-DRE-70479 https://reactome.org/PathwayBrowser/#/R-DRE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Danio rerio 43474 R-DRE-70482 https://reactome.org/PathwayBrowser/#/R-DRE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Danio rerio 43474 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 43474 R-DRE-70606 https://reactome.org/PathwayBrowser/#/R-DRE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Danio rerio 43474 R-DRE-70997 https://reactome.org/PathwayBrowser/#/R-DRE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Danio rerio 43474 R-DRE-71031 https://reactome.org/PathwayBrowser/#/R-DRE-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Danio rerio 43474 R-DRE-71732 https://reactome.org/PathwayBrowser/#/R-DRE-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Danio rerio 43474 R-DRE-72621 https://reactome.org/PathwayBrowser/#/R-DRE-72621 Ribosomal scanning IEA Danio rerio 43474 R-DRE-73647 https://reactome.org/PathwayBrowser/#/R-DRE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Danio rerio 43474 R-DRE-73805 https://reactome.org/PathwayBrowser/#/R-DRE-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Danio rerio 43474 R-DRE-73810 https://reactome.org/PathwayBrowser/#/R-DRE-73810 FGAM + ATP => AIR + ADP + Pi IEA Danio rerio 43474 R-DRE-73814 https://reactome.org/PathwayBrowser/#/R-DRE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Danio rerio 43474 R-DRE-74242 https://reactome.org/PathwayBrowser/#/R-DRE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Danio rerio 43474 R-DRE-74249 https://reactome.org/PathwayBrowser/#/R-DRE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Danio rerio 43474 R-DRE-74372 https://reactome.org/PathwayBrowser/#/R-DRE-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Danio rerio 43474 R-DRE-74376 https://reactome.org/PathwayBrowser/#/R-DRE-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Danio rerio 43474 R-DRE-75848 https://reactome.org/PathwayBrowser/#/R-DRE-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Danio rerio 43474 R-DRE-77078 https://reactome.org/PathwayBrowser/#/R-DRE-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Danio rerio 43474 R-DRE-8849082 https://reactome.org/PathwayBrowser/#/R-DRE-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Danio rerio 43474 R-DRE-8849969 https://reactome.org/PathwayBrowser/#/R-DRE-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Danio rerio 43474 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 43474 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 43474 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 43474 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 43474 R-DRE-8854173 https://reactome.org/PathwayBrowser/#/R-DRE-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Danio rerio 43474 R-DRE-8854255 https://reactome.org/PathwayBrowser/#/R-DRE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Danio rerio 43474 R-DRE-8854329 https://reactome.org/PathwayBrowser/#/R-DRE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Danio rerio 43474 R-DRE-8854604 https://reactome.org/PathwayBrowser/#/R-DRE-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Danio rerio 43474 R-DRE-8854612 https://reactome.org/PathwayBrowser/#/R-DRE-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Danio rerio 43474 R-DRE-8863804 https://reactome.org/PathwayBrowser/#/R-DRE-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Danio rerio 43474 R-DRE-8864036 https://reactome.org/PathwayBrowser/#/R-DRE-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Danio rerio 43474 R-DRE-8864125 https://reactome.org/PathwayBrowser/#/R-DRE-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Danio rerio 43474 R-DRE-8878654 https://reactome.org/PathwayBrowser/#/R-DRE-8878654 ACP6 hydrolyses MYS-LPA IEA Danio rerio 43474 R-DRE-8878787 https://reactome.org/PathwayBrowser/#/R-DRE-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Danio rerio 43474 R-DRE-8940070 https://reactome.org/PathwayBrowser/#/R-DRE-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Danio rerio 43474 R-DRE-8940074 https://reactome.org/PathwayBrowser/#/R-DRE-8940074 NT5E:Zn2+ hydrolyses NMN IEA Danio rerio 43474 R-DRE-8951498 https://reactome.org/PathwayBrowser/#/R-DRE-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Danio rerio 43474 R-DRE-8952137 https://reactome.org/PathwayBrowser/#/R-DRE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Danio rerio 43474 R-DRE-8953499 https://reactome.org/PathwayBrowser/#/R-DRE-8953499 IMPAD1 hydrolyses PAP to AMP IEA Danio rerio 43474 R-DRE-8959510 https://reactome.org/PathwayBrowser/#/R-DRE-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Danio rerio 43474 R-DRE-8981637 https://reactome.org/PathwayBrowser/#/R-DRE-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Danio rerio 43474 R-DRE-8982020 https://reactome.org/PathwayBrowser/#/R-DRE-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Danio rerio 43474 R-DRE-8982025 https://reactome.org/PathwayBrowser/#/R-DRE-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Danio rerio 43474 R-DRE-9013144 https://reactome.org/PathwayBrowser/#/R-DRE-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Danio rerio 43474 R-DRE-9013161 https://reactome.org/PathwayBrowser/#/R-DRE-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Danio rerio 43474 R-DRE-9013437 https://reactome.org/PathwayBrowser/#/R-DRE-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Danio rerio 43474 R-DRE-9014295 https://reactome.org/PathwayBrowser/#/R-DRE-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Danio rerio 43474 R-DRE-9014434 https://reactome.org/PathwayBrowser/#/R-DRE-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Danio rerio 43474 R-DRE-9018745 https://reactome.org/PathwayBrowser/#/R-DRE-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Danio rerio 43474 R-DRE-9018806 https://reactome.org/PathwayBrowser/#/R-DRE-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Danio rerio 43474 R-DRE-9018814 https://reactome.org/PathwayBrowser/#/R-DRE-9018814 RHOT1 hydrolyzes GTP IEA Danio rerio 43474 R-DRE-9018826 https://reactome.org/PathwayBrowser/#/R-DRE-9018826 RHOT2 hydrolyzes GTP IEA Danio rerio 43474 R-DRE-917841 https://reactome.org/PathwayBrowser/#/R-DRE-917841 Acidification of Tf:TfR1 containing endosome IEA Danio rerio 43474 R-DRE-936802 https://reactome.org/PathwayBrowser/#/R-DRE-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Danio rerio 43474 R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 43474 R-DRE-939763 https://reactome.org/PathwayBrowser/#/R-DRE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Danio rerio 43474 R-DRE-947591 https://reactome.org/PathwayBrowser/#/R-DRE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Danio rerio 43474 R-DRE-9624893 https://reactome.org/PathwayBrowser/#/R-DRE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Danio rerio 43474 R-DRE-9640195 https://reactome.org/PathwayBrowser/#/R-DRE-9640195 RRAGA,B hydrolyzes GTP IEA Danio rerio 43474 R-DRE-9645598 https://reactome.org/PathwayBrowser/#/R-DRE-9645598 RRAGC,D hydrolyzes GTP IEA Danio rerio 43474 R-DRE-9658445 https://reactome.org/PathwayBrowser/#/R-DRE-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Danio rerio 43474 R-DRE-9684118 https://reactome.org/PathwayBrowser/#/R-DRE-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Danio rerio 43474 R-DRE-9693282 https://reactome.org/PathwayBrowser/#/R-DRE-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Danio rerio 43474 R-DRE-9750546 https://reactome.org/PathwayBrowser/#/R-DRE-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 43474 R-DRE-9750617 https://reactome.org/PathwayBrowser/#/R-DRE-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 43474 R-DRE-9750656 https://reactome.org/PathwayBrowser/#/R-DRE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Danio rerio 43474 R-DRE-9753278 https://reactome.org/PathwayBrowser/#/R-DRE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 43474 R-DRE-9753283 https://reactome.org/PathwayBrowser/#/R-DRE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 43474 R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 43474 R-DRE-977324 https://reactome.org/PathwayBrowser/#/R-DRE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Danio rerio 43474 R-DRE-9839105 https://reactome.org/PathwayBrowser/#/R-DRE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Danio rerio 43474 R-DRE-9839113 https://reactome.org/PathwayBrowser/#/R-DRE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Danio rerio 43474 R-DRE-9861725 https://reactome.org/PathwayBrowser/#/R-DRE-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Danio rerio 43474 R-DRE-997326 https://reactome.org/PathwayBrowser/#/R-DRE-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Danio rerio 43474 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 43474 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 43474 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 43474 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 43474 R-GGA-109415 https://reactome.org/PathwayBrowser/#/R-GGA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Gallus gallus 43474 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 43474 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 43474 R-GGA-111215 https://reactome.org/PathwayBrowser/#/R-GGA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Gallus gallus 43474 R-GGA-111524 https://reactome.org/PathwayBrowser/#/R-GGA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Gallus gallus 43474 R-GGA-112037 https://reactome.org/PathwayBrowser/#/R-GGA-112037 Inactivation of PLC beta IEA Gallus gallus 43474 R-GGA-1169192 https://reactome.org/PathwayBrowser/#/R-GGA-1169192 PTP1B dephosphorylates GHR IEA Gallus gallus 43474 R-GGA-1237129 https://reactome.org/PathwayBrowser/#/R-GGA-1237129 Acireductone is created IEA Gallus gallus 43474 R-GGA-1237160 https://reactome.org/PathwayBrowser/#/R-GGA-1237160 MTA is cleaved and phosphorylated IEA Gallus gallus 43474 R-GGA-1369028 https://reactome.org/PathwayBrowser/#/R-GGA-1369028 ABCAs mediate lipid efflux IEA Gallus gallus 43474 R-GGA-1369052 https://reactome.org/PathwayBrowser/#/R-GGA-1369052 ABCAs mediate lipid influx IEA Gallus gallus 43474 R-GGA-1369065 https://reactome.org/PathwayBrowser/#/R-GGA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Gallus gallus 43474 R-GGA-1454916 https://reactome.org/PathwayBrowser/#/R-GGA-1454916 The ABCC family mediates organic anion transport IEA Gallus gallus 43474 R-GGA-1454928 https://reactome.org/PathwayBrowser/#/R-GGA-1454928 ABCG4 may mediate cholesterol efflux IEA Gallus gallus 43474 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 43474 R-GGA-1467466 https://reactome.org/PathwayBrowser/#/R-GGA-1467466 ABCA4 mediates atRAL transport IEA Gallus gallus 43474 R-GGA-1483096 https://reactome.org/PathwayBrowser/#/R-GGA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Gallus gallus 43474 R-GGA-1483159 https://reactome.org/PathwayBrowser/#/R-GGA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Gallus gallus 43474 R-GGA-1483203 https://reactome.org/PathwayBrowser/#/R-GGA-1483203 PA is dephosphorylated to DAG by LPIN IEA Gallus gallus 43474 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus 43474 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus 43474 R-GGA-164840 https://reactome.org/PathwayBrowser/#/R-GGA-164840 ADP and Pi bind to ATPase IEA Gallus gallus 43474 R-GGA-1675795 https://reactome.org/PathwayBrowser/#/R-GGA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Gallus gallus 43474 R-GGA-1675824 https://reactome.org/PathwayBrowser/#/R-GGA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Gallus gallus 43474 R-GGA-1675836 https://reactome.org/PathwayBrowser/#/R-GGA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Gallus gallus 43474 R-GGA-1675949 https://reactome.org/PathwayBrowser/#/R-GGA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Gallus gallus 43474 R-GGA-1675988 https://reactome.org/PathwayBrowser/#/R-GGA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Gallus gallus 43474 R-GGA-1675994 https://reactome.org/PathwayBrowser/#/R-GGA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Gallus gallus 43474 R-GGA-1676005 https://reactome.org/PathwayBrowser/#/R-GGA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Gallus gallus 43474 R-GGA-1676020 https://reactome.org/PathwayBrowser/#/R-GGA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Gallus gallus 43474 R-GGA-1676065 https://reactome.org/PathwayBrowser/#/R-GGA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Gallus gallus 43474 R-GGA-1676105 https://reactome.org/PathwayBrowser/#/R-GGA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Gallus gallus 43474 R-GGA-1676114 https://reactome.org/PathwayBrowser/#/R-GGA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Gallus gallus 43474 R-GGA-1676124 https://reactome.org/PathwayBrowser/#/R-GGA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Gallus gallus 43474 R-GGA-1676133 https://reactome.org/PathwayBrowser/#/R-GGA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Gallus gallus 43474 R-GGA-1676141 https://reactome.org/PathwayBrowser/#/R-GGA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Gallus gallus 43474 R-GGA-1676149 https://reactome.org/PathwayBrowser/#/R-GGA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Gallus gallus 43474 R-GGA-1676162 https://reactome.org/PathwayBrowser/#/R-GGA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Gallus gallus 43474 R-GGA-1676164 https://reactome.org/PathwayBrowser/#/R-GGA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Gallus gallus 43474 R-GGA-1676174 https://reactome.org/PathwayBrowser/#/R-GGA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Gallus gallus 43474 R-GGA-1676177 https://reactome.org/PathwayBrowser/#/R-GGA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Gallus gallus 43474 R-GGA-1676203 https://reactome.org/PathwayBrowser/#/R-GGA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Gallus gallus 43474 R-GGA-1676204 https://reactome.org/PathwayBrowser/#/R-GGA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Gallus gallus 43474 R-GGA-170158 https://reactome.org/PathwayBrowser/#/R-GGA-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Gallus gallus 43474 R-GGA-170161 https://reactome.org/PathwayBrowser/#/R-GGA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Gallus gallus 43474 R-GGA-170666 https://reactome.org/PathwayBrowser/#/R-GGA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus 43474 R-GGA-170685 https://reactome.org/PathwayBrowser/#/R-GGA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus 43474 R-GGA-170686 https://reactome.org/PathwayBrowser/#/R-GGA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Gallus gallus 43474 R-GGA-174110 https://reactome.org/PathwayBrowser/#/R-GGA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Gallus gallus 43474 R-GGA-174391 https://reactome.org/PathwayBrowser/#/R-GGA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Gallus gallus 43474 R-GGA-174394 https://reactome.org/PathwayBrowser/#/R-GGA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Gallus gallus 43474 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus 43474 R-GGA-176606 https://reactome.org/PathwayBrowser/#/R-GGA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Gallus gallus 43474 R-GGA-177923 https://reactome.org/PathwayBrowser/#/R-GGA-177923 Sustained activation of SRC kinase by SHP2 IEA Gallus gallus 43474 R-GGA-177924 https://reactome.org/PathwayBrowser/#/R-GGA-177924 Dephosphorylation of Gab1 by SHP2 IEA Gallus gallus 43474 R-GGA-177926 https://reactome.org/PathwayBrowser/#/R-GGA-177926 Dephosphorylation of PAG by SHP2 IEA Gallus gallus 43474 R-GGA-177935 https://reactome.org/PathwayBrowser/#/R-GGA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Gallus gallus 43474 R-GGA-1855154 https://reactome.org/PathwayBrowser/#/R-GGA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 43474 R-GGA-1855159 https://reactome.org/PathwayBrowser/#/R-GGA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Gallus gallus 43474 R-GGA-1855163 https://reactome.org/PathwayBrowser/#/R-GGA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Gallus gallus 43474 R-GGA-1855165 https://reactome.org/PathwayBrowser/#/R-GGA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 43474 R-GGA-1855166 https://reactome.org/PathwayBrowser/#/R-GGA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Gallus gallus 43474 R-GGA-1855171 https://reactome.org/PathwayBrowser/#/R-GGA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Gallus gallus 43474 R-GGA-1855174 https://reactome.org/PathwayBrowser/#/R-GGA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Gallus gallus 43474 R-GGA-1855180 https://reactome.org/PathwayBrowser/#/R-GGA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Gallus gallus 43474 R-GGA-1855198 https://reactome.org/PathwayBrowser/#/R-GGA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 43474 R-GGA-1855200 https://reactome.org/PathwayBrowser/#/R-GGA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Gallus gallus 43474 R-GGA-1855202 https://reactome.org/PathwayBrowser/#/R-GGA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Gallus gallus 43474 R-GGA-1855205 https://reactome.org/PathwayBrowser/#/R-GGA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Gallus gallus 43474 R-GGA-1855208 https://reactome.org/PathwayBrowser/#/R-GGA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Gallus gallus 43474 R-GGA-1855210 https://reactome.org/PathwayBrowser/#/R-GGA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 43474 R-GGA-1855211 https://reactome.org/PathwayBrowser/#/R-GGA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 43474 R-GGA-1855213 https://reactome.org/PathwayBrowser/#/R-GGA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Gallus gallus 43474 R-GGA-1855218 https://reactome.org/PathwayBrowser/#/R-GGA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Gallus gallus 43474 R-GGA-1855219 https://reactome.org/PathwayBrowser/#/R-GGA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 43474 R-GGA-1855222 https://reactome.org/PathwayBrowser/#/R-GGA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Gallus gallus 43474 R-GGA-1855225 https://reactome.org/PathwayBrowser/#/R-GGA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Gallus gallus 43474 R-GGA-1855232 https://reactome.org/PathwayBrowser/#/R-GGA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Gallus gallus 43474 R-GGA-187588 https://reactome.org/PathwayBrowser/#/R-GGA-187588 carbamoyl phosphate + ornithine => citrulline + orthophosphate TAS Gallus gallus 43474 R-GGA-191414 https://reactome.org/PathwayBrowser/#/R-GGA-191414 MVD decarboxylates MVA5PP to IPPP IEA Gallus gallus 43474 R-GGA-193362 https://reactome.org/PathwayBrowser/#/R-GGA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Gallus gallus 43474 R-GGA-194153 https://reactome.org/PathwayBrowser/#/R-GGA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Gallus gallus 43474 R-GGA-196950 https://reactome.org/PathwayBrowser/#/R-GGA-196950 2xTRAP hydrolyzes FMN to RIB IEA Gallus gallus 43474 R-GGA-197958 https://reactome.org/PathwayBrowser/#/R-GGA-197958 FPGS-2 transforms THF to THFPG IEA Gallus gallus 43474 R-GGA-198513 https://reactome.org/PathwayBrowser/#/R-GGA-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Gallus gallus 43474 R-GGA-199425 https://reactome.org/PathwayBrowser/#/R-GGA-199425 PHLPP dephosphorylates S473 in AKT IEA Gallus gallus 43474 R-GGA-199456 https://reactome.org/PathwayBrowser/#/R-GGA-199456 PTEN dephosphorylates PIP3 IEA Gallus gallus 43474 R-GGA-200555 https://reactome.org/PathwayBrowser/#/R-GGA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Gallus gallus 43474 R-GGA-200681 https://reactome.org/PathwayBrowser/#/R-GGA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Gallus gallus 43474 R-GGA-200682 https://reactome.org/PathwayBrowser/#/R-GGA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Gallus gallus 43474 R-GGA-200711 https://reactome.org/PathwayBrowser/#/R-GGA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Gallus gallus 43474 R-GGA-202214 https://reactome.org/PathwayBrowser/#/R-GGA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Gallus gallus 43474 R-GGA-202237 https://reactome.org/PathwayBrowser/#/R-GGA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Gallus gallus 43474 R-GGA-2023971 https://reactome.org/PathwayBrowser/#/R-GGA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 43474 R-GGA-2023973 https://reactome.org/PathwayBrowser/#/R-GGA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 43474 R-GGA-2029468 https://reactome.org/PathwayBrowser/#/R-GGA-2029468 Conversion of PA into DAG by PAP-1 IEA Gallus gallus 43474 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus 43474 R-GGA-203797 https://reactome.org/PathwayBrowser/#/R-GGA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Gallus gallus 43474 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus 43474 R-GGA-204169 https://reactome.org/PathwayBrowser/#/R-GGA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Gallus gallus 43474 R-GGA-2130641 https://reactome.org/PathwayBrowser/#/R-GGA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Gallus gallus 43474 R-GGA-2130725 https://reactome.org/PathwayBrowser/#/R-GGA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Gallus gallus 43474 R-GGA-216723 https://reactome.org/PathwayBrowser/#/R-GGA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Gallus gallus 43474 R-GGA-216757 https://reactome.org/PathwayBrowser/#/R-GGA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Gallus gallus 43474 R-GGA-2187401 https://reactome.org/PathwayBrowser/#/R-GGA-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Gallus gallus 43474 R-GGA-2395876 https://reactome.org/PathwayBrowser/#/R-GGA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Gallus gallus 43474 R-GGA-2408551 https://reactome.org/PathwayBrowser/#/R-GGA-2408551 SeMet is converted to AdoSeMet by MAT IEA Gallus gallus 43474 R-GGA-2529015 https://reactome.org/PathwayBrowser/#/R-GGA-2529015 Dephosphorylation of CK2-modified condensin I IEA Gallus gallus 43474 R-GGA-265783 https://reactome.org/PathwayBrowser/#/R-GGA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Gallus gallus 43474 R-GGA-266082 https://reactome.org/PathwayBrowser/#/R-GGA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Gallus gallus 43474 R-GGA-2682349 https://reactome.org/PathwayBrowser/#/R-GGA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Gallus gallus 43474 R-GGA-2730849 https://reactome.org/PathwayBrowser/#/R-GGA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Gallus gallus 43474 R-GGA-2995388 https://reactome.org/PathwayBrowser/#/R-GGA-2995388 PP2A dephosphorylates BANF1 IEA Gallus gallus 43474 R-GGA-3002811 https://reactome.org/PathwayBrowser/#/R-GGA-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Gallus gallus 43474 R-GGA-3095901 https://reactome.org/PathwayBrowser/#/R-GGA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Gallus gallus 43474 R-GGA-3257122 https://reactome.org/PathwayBrowser/#/R-GGA-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Gallus gallus 43474 R-GGA-3262512 https://reactome.org/PathwayBrowser/#/R-GGA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Gallus gallus 43474 R-GGA-3266566 https://reactome.org/PathwayBrowser/#/R-GGA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Gallus gallus 43474 R-GGA-3371422 https://reactome.org/PathwayBrowser/#/R-GGA-3371422 ATP hydrolysis by HSP70 IEA Gallus gallus 43474 R-GGA-352921 https://reactome.org/PathwayBrowser/#/R-GGA-352921 1,3-bisphosphoglycerate + NADH + H+ <=> glyceraldehyde 3-phosphate + NAD+ + phosphate TAS Gallus gallus 43474 R-GGA-352956 https://reactome.org/PathwayBrowser/#/R-GGA-352956 glyceraldehyde 3-phosphate + NAD+ + phosphate <=> 1,3-bisphosphoglycerate + NADH + H+ TAS Gallus gallus 43474 R-GGA-353058 https://reactome.org/PathwayBrowser/#/R-GGA-353058 glucose 6-phosphate + H2O => glucose + phosphate IEA Gallus gallus 43474 R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 43474 R-GGA-372388 https://reactome.org/PathwayBrowser/#/R-GGA-372388 fructose 1,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate TAS Gallus gallus 43474 R-GGA-372425 https://reactome.org/PathwayBrowser/#/R-GGA-372425 fructose 2,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate TAS Gallus gallus 43474 R-GGA-372843 https://reactome.org/PathwayBrowser/#/R-GGA-372843 SLC25A10 mediates exchange of malate and phosphate IEA Gallus gallus 43474 R-GGA-372852 https://reactome.org/PathwayBrowser/#/R-GGA-372852 malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix] IEA Gallus gallus 43474 R-GGA-372977 https://reactome.org/PathwayBrowser/#/R-GGA-372977 succinylCoA + ADP + Pi <=> succinate + CoASH + ATP TAS Gallus gallus 43474 R-GGA-372980 https://reactome.org/PathwayBrowser/#/R-GGA-372980 succinylCoA + GDP + Pi <=> succinate + CoASH + GTP TAS Gallus gallus 43474 R-GGA-373134 https://reactome.org/PathwayBrowser/#/R-GGA-373134 succinate + CoASH + ATP <=> succinylCoA + ADP + Pi TAS Gallus gallus 43474 R-GGA-373148 https://reactome.org/PathwayBrowser/#/R-GGA-373148 succinate + CoASH + GTP <=> succinylCoA + GDP + Pi TAS Gallus gallus 43474 R-GGA-376886 https://reactome.org/PathwayBrowser/#/R-GGA-376886 Efflux of glucose and orthophosphate from the endoplasmic reticulum TAS Gallus gallus 43474 R-GGA-377643 https://reactome.org/PathwayBrowser/#/R-GGA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Gallus gallus 43474 R-GGA-3781011 https://reactome.org/PathwayBrowser/#/R-GGA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Gallus gallus 43474 R-GGA-3781018 https://reactome.org/PathwayBrowser/#/R-GGA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Gallus gallus 43474 R-GGA-380949 https://reactome.org/PathwayBrowser/#/R-GGA-380949 AMPK is dephosphorylated IEA Gallus gallus 43474 R-GGA-380979 https://reactome.org/PathwayBrowser/#/R-GGA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Gallus gallus 43474 R-GGA-382560 https://reactome.org/PathwayBrowser/#/R-GGA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Gallus gallus 43474 R-GGA-382575 https://reactome.org/PathwayBrowser/#/R-GGA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Gallus gallus 43474 R-GGA-383190 https://reactome.org/PathwayBrowser/#/R-GGA-383190 HCO3- transport through ion channel IEA Gallus gallus 43474 R-GGA-390593 https://reactome.org/PathwayBrowser/#/R-GGA-390593 ATP Hydrolysis By Myosin IEA Gallus gallus 43474 R-GGA-4084976 https://reactome.org/PathwayBrowser/#/R-GGA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Gallus gallus 43474 R-GGA-4084989 https://reactome.org/PathwayBrowser/#/R-GGA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Gallus gallus 43474 R-GGA-4093339 https://reactome.org/PathwayBrowser/#/R-GGA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Gallus gallus 43474 R-GGA-416559 https://reactome.org/PathwayBrowser/#/R-GGA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Gallus gallus 43474 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus 43474 R-GGA-416985 https://reactome.org/PathwayBrowser/#/R-GGA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Gallus gallus 43474 R-GGA-419144 https://reactome.org/PathwayBrowser/#/R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate TAS Gallus gallus 43474 R-GGA-419153 https://reactome.org/PathwayBrowser/#/R-GGA-419153 5-phosphoribosylamine + glycine + ATP <=> 5-phosphoribosylglycinamide (GAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 43474 R-GGA-419157 https://reactome.org/PathwayBrowser/#/R-GGA-419157 5'-phosphoribosylformylglycinamidine (FGAM) + ATP => 5'-phosphoribosyl-5-aminoimidazole (AIR) + ADP + orthophosphate TAS Gallus gallus 43474 R-GGA-419223 https://reactome.org/PathwayBrowser/#/R-GGA-419223 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 43474 R-GGA-419440 https://reactome.org/PathwayBrowser/#/R-GGA-419440 L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate IEA Gallus gallus 43474 R-GGA-419451 https://reactome.org/PathwayBrowser/#/R-GGA-419451 carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate IEA Gallus gallus 43474 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus 43474 R-GGA-421174 https://reactome.org/PathwayBrowser/#/R-GGA-421174 inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate IEA Gallus gallus 43474 R-GGA-421179 https://reactome.org/PathwayBrowser/#/R-GGA-421179 inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate IEA Gallus gallus 43474 R-GGA-421201 https://reactome.org/PathwayBrowser/#/R-GGA-421201 inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate IEA Gallus gallus 43474 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus 43474 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus 43474 R-GGA-427605 https://reactome.org/PathwayBrowser/#/R-GGA-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Gallus gallus 43474 R-GGA-427656 https://reactome.org/PathwayBrowser/#/R-GGA-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Gallus gallus 43474 R-GGA-428664 https://reactome.org/PathwayBrowser/#/R-GGA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Gallus gallus 43474 R-GGA-428690 https://reactome.org/PathwayBrowser/#/R-GGA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Gallus gallus 43474 R-GGA-428696 https://reactome.org/PathwayBrowser/#/R-GGA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Gallus gallus 43474 R-GGA-429157 https://reactome.org/PathwayBrowser/#/R-GGA-429157 ABCC4 accumulation of dense granule contents IEA Gallus gallus 43474 R-GGA-432706 https://reactome.org/PathwayBrowser/#/R-GGA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Gallus gallus 43474 R-GGA-432707 https://reactome.org/PathwayBrowser/#/R-GGA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Gallus gallus 43474 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus 43474 R-GGA-446200 https://reactome.org/PathwayBrowser/#/R-GGA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Gallus gallus 43474 R-GGA-449937 https://reactome.org/PathwayBrowser/#/R-GGA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Gallus gallus 43474 R-GGA-4551451 https://reactome.org/PathwayBrowser/#/R-GGA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Gallus gallus 43474 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 43474 R-GGA-504054 https://reactome.org/PathwayBrowser/#/R-GGA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Gallus gallus 43474 R-GGA-508040 https://reactome.org/PathwayBrowser/#/R-GGA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Gallus gallus 43474 R-GGA-508308 https://reactome.org/PathwayBrowser/#/R-GGA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Gallus gallus 43474 R-GGA-5221130 https://reactome.org/PathwayBrowser/#/R-GGA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Gallus gallus 43474 R-GGA-5223313 https://reactome.org/PathwayBrowser/#/R-GGA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Gallus gallus 43474 R-GGA-5223317 https://reactome.org/PathwayBrowser/#/R-GGA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Gallus gallus 43474 R-GGA-5251989 https://reactome.org/PathwayBrowser/#/R-GGA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Gallus gallus 43474 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Gallus gallus 43474 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus 43474 R-GGA-555065 https://reactome.org/PathwayBrowser/#/R-GGA-555065 Formation of clathrin coated vesicle IEA Gallus gallus 43474 R-GGA-5603114 https://reactome.org/PathwayBrowser/#/R-GGA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Gallus gallus 43474 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 43474 R-GGA-5623513 https://reactome.org/PathwayBrowser/#/R-GGA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Gallus gallus 43474 R-GGA-5628905 https://reactome.org/PathwayBrowser/#/R-GGA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Gallus gallus 43474 R-GGA-5675373 https://reactome.org/PathwayBrowser/#/R-GGA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Gallus gallus 43474 R-GGA-5675376 https://reactome.org/PathwayBrowser/#/R-GGA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Gallus gallus 43474 R-GGA-5678706 https://reactome.org/PathwayBrowser/#/R-GGA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Gallus gallus 43474 R-GGA-5678863 https://reactome.org/PathwayBrowser/#/R-GGA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Gallus gallus 43474 R-GGA-5679041 https://reactome.org/PathwayBrowser/#/R-GGA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Gallus gallus 43474 R-GGA-5682285 https://reactome.org/PathwayBrowser/#/R-GGA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Gallus gallus 43474 R-GGA-5683714 https://reactome.org/PathwayBrowser/#/R-GGA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Gallus gallus 43474 R-GGA-5683925 https://reactome.org/PathwayBrowser/#/R-GGA-5683925 ULK1 is dephosphorylated IEA Gallus gallus 43474 R-GGA-5683967 https://reactome.org/PathwayBrowser/#/R-GGA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Gallus gallus 43474 R-GGA-5687758 https://reactome.org/PathwayBrowser/#/R-GGA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Gallus gallus 43474 R-GGA-5690996 https://reactome.org/PathwayBrowser/#/R-GGA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Gallus gallus 43474 R-GGA-5692462 https://reactome.org/PathwayBrowser/#/R-GGA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Gallus gallus 43474 R-GGA-5692480 https://reactome.org/PathwayBrowser/#/R-GGA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Gallus gallus 43474 R-GGA-5692754 https://reactome.org/PathwayBrowser/#/R-GGA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Gallus gallus 43474 R-GGA-5693153 https://reactome.org/PathwayBrowser/#/R-GGA-5693153 PPM1K dephosphorylates p-BCKDH IEA Gallus gallus 43474 R-GGA-5694126 https://reactome.org/PathwayBrowser/#/R-GGA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Gallus gallus 43474 R-GGA-5694421 https://reactome.org/PathwayBrowser/#/R-GGA-5694421 PP6 dephosphorylates SEC24 IEA Gallus gallus 43474 R-GGA-5694425 https://reactome.org/PathwayBrowser/#/R-GGA-5694425 NSF ATPase activity dissociates cis-SNARE IEA Gallus gallus 43474 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus 43474 R-GGA-5696408 https://reactome.org/PathwayBrowser/#/R-GGA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Gallus gallus 43474 R-GGA-5696415 https://reactome.org/PathwayBrowser/#/R-GGA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Gallus gallus 43474 R-GGA-5696839 https://reactome.org/PathwayBrowser/#/R-GGA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Gallus gallus 43474 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus 43474 R-GGA-6786245 https://reactome.org/PathwayBrowser/#/R-GGA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Gallus gallus 43474 R-GGA-6788295 https://reactome.org/PathwayBrowser/#/R-GGA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Gallus gallus 43474 R-GGA-6788912 https://reactome.org/PathwayBrowser/#/R-GGA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Gallus gallus 43474 R-GGA-6797630 https://reactome.org/PathwayBrowser/#/R-GGA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Gallus gallus 43474 R-GGA-6801342 https://reactome.org/PathwayBrowser/#/R-GGA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Gallus gallus 43474 R-GGA-6801456 https://reactome.org/PathwayBrowser/#/R-GGA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Gallus gallus 43474 R-GGA-6803545 https://reactome.org/PathwayBrowser/#/R-GGA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Gallus gallus 43474 R-GGA-6806967 https://reactome.org/PathwayBrowser/#/R-GGA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Gallus gallus 43474 R-GGA-6807008 https://reactome.org/PathwayBrowser/#/R-GGA-6807008 PTPRJ dephosphorylates MET IEA Gallus gallus 43474 R-GGA-6807027 https://reactome.org/PathwayBrowser/#/R-GGA-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Gallus gallus 43474 R-GGA-6809015 https://reactome.org/PathwayBrowser/#/R-GGA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Gallus gallus 43474 R-GGA-6809320 https://reactome.org/PathwayBrowser/#/R-GGA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Gallus gallus 43474 R-GGA-6809325 https://reactome.org/PathwayBrowser/#/R-GGA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Gallus gallus 43474 R-GGA-6809720 https://reactome.org/PathwayBrowser/#/R-GGA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Gallus gallus 43474 R-GGA-6809777 https://reactome.org/PathwayBrowser/#/R-GGA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Gallus gallus 43474 R-GGA-6809778 https://reactome.org/PathwayBrowser/#/R-GGA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Gallus gallus 43474 R-GGA-6811422 https://reactome.org/PathwayBrowser/#/R-GGA-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Gallus gallus 43474 R-GGA-6814120 https://reactome.org/PathwayBrowser/#/R-GGA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Gallus gallus 43474 R-GGA-68954 https://reactome.org/PathwayBrowser/#/R-GGA-68954 Mcm2-7 is phosphorylated by DDK IEA Gallus gallus 43474 R-GGA-69199 https://reactome.org/PathwayBrowser/#/R-GGA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Gallus gallus 43474 R-GGA-70262 https://reactome.org/PathwayBrowser/#/R-GGA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Gallus gallus 43474 R-GGA-70449 https://reactome.org/PathwayBrowser/#/R-GGA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Gallus gallus 43474 R-GGA-70479 https://reactome.org/PathwayBrowser/#/R-GGA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Gallus gallus 43474 R-GGA-70482 https://reactome.org/PathwayBrowser/#/R-GGA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Gallus gallus 43474 R-GGA-70555 https://reactome.org/PathwayBrowser/#/R-GGA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Gallus gallus 43474 R-GGA-70560 https://reactome.org/PathwayBrowser/#/R-GGA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Gallus gallus 43474 R-GGA-70606 https://reactome.org/PathwayBrowser/#/R-GGA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Gallus gallus 43474 R-GGA-70773 https://reactome.org/PathwayBrowser/#/R-GGA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Gallus gallus 43474 R-GGA-70997 https://reactome.org/PathwayBrowser/#/R-GGA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Gallus gallus 43474 R-GGA-71031 https://reactome.org/PathwayBrowser/#/R-GGA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Gallus gallus 43474 R-GGA-71732 https://reactome.org/PathwayBrowser/#/R-GGA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Gallus gallus 43474 R-GGA-71775 https://reactome.org/PathwayBrowser/#/R-GGA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Gallus gallus 43474 R-GGA-71825 https://reactome.org/PathwayBrowser/#/R-GGA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Gallus gallus 43474 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus 43474 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus 43474 R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus 43474 R-GGA-73805 https://reactome.org/PathwayBrowser/#/R-GGA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Gallus gallus 43474 R-GGA-73810 https://reactome.org/PathwayBrowser/#/R-GGA-73810 FGAM + ATP => AIR + ADP + Pi IEA Gallus gallus 43474 R-GGA-73814 https://reactome.org/PathwayBrowser/#/R-GGA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Gallus gallus 43474 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 43474 R-GGA-74372 https://reactome.org/PathwayBrowser/#/R-GGA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Gallus gallus 43474 R-GGA-74376 https://reactome.org/PathwayBrowser/#/R-GGA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Gallus gallus 43474 R-GGA-74733 https://reactome.org/PathwayBrowser/#/R-GGA-74733 Insulin receptor de-phosphorylation IEA Gallus gallus 43474 R-GGA-74948 https://reactome.org/PathwayBrowser/#/R-GGA-74948 PP2A dephosphorylates p-RHO to RHO IEA Gallus gallus 43474 R-GGA-75848 https://reactome.org/PathwayBrowser/#/R-GGA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Gallus gallus 43474 R-GGA-75851 https://reactome.org/PathwayBrowser/#/R-GGA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Gallus gallus 43474 R-GGA-75899 https://reactome.org/PathwayBrowser/#/R-GGA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Gallus gallus 43474 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus 43474 R-GGA-77078 https://reactome.org/PathwayBrowser/#/R-GGA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Gallus gallus 43474 R-GGA-8848053 https://reactome.org/PathwayBrowser/#/R-GGA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Gallus gallus 43474 R-GGA-8849082 https://reactome.org/PathwayBrowser/#/R-GGA-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Gallus gallus 43474 R-GGA-8849969 https://reactome.org/PathwayBrowser/#/R-GGA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Gallus gallus 43474 R-GGA-8850846 https://reactome.org/PathwayBrowser/#/R-GGA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Gallus gallus 43474 R-GGA-8850854 https://reactome.org/PathwayBrowser/#/R-GGA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Gallus gallus 43474 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 43474 R-GGA-8851110 https://reactome.org/PathwayBrowser/#/R-GGA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Gallus gallus 43474 R-GGA-8851129 https://reactome.org/PathwayBrowser/#/R-GGA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Gallus gallus 43474 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 43474 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 43474 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 43474 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 43474 R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 43474 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 43474 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 43474 R-GGA-8852200 https://reactome.org/PathwayBrowser/#/R-GGA-8852200 Inactivation of LCK by PTPN22 IEA Gallus gallus 43474 R-GGA-8854173 https://reactome.org/PathwayBrowser/#/R-GGA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Gallus gallus 43474 R-GGA-8854255 https://reactome.org/PathwayBrowser/#/R-GGA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 43474 R-GGA-8854329 https://reactome.org/PathwayBrowser/#/R-GGA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 43474 R-GGA-8854604 https://reactome.org/PathwayBrowser/#/R-GGA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Gallus gallus 43474 R-GGA-8854612 https://reactome.org/PathwayBrowser/#/R-GGA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Gallus gallus 43474 R-GGA-8855381 https://reactome.org/PathwayBrowser/#/R-GGA-8855381 PTPN22 dephosphorylates ZAP70 IEA Gallus gallus 43474 R-GGA-8863804 https://reactome.org/PathwayBrowser/#/R-GGA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Gallus gallus 43474 R-GGA-8864029 https://reactome.org/PathwayBrowser/#/R-GGA-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Gallus gallus 43474 R-GGA-8864036 https://reactome.org/PathwayBrowser/#/R-GGA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Gallus gallus 43474 R-GGA-8864125 https://reactome.org/PathwayBrowser/#/R-GGA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Gallus gallus 43474 R-GGA-8866542 https://reactome.org/PathwayBrowser/#/R-GGA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Gallus gallus 43474 R-GGA-8867047 https://reactome.org/PathwayBrowser/#/R-GGA-8867047 PTPN3 dephosphorylates EPS15 IEA Gallus gallus 43474 R-GGA-8867658 https://reactome.org/PathwayBrowser/#/R-GGA-8867658 PTPN3 dephosphorylates MAPK12 IEA Gallus gallus 43474 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus 43474 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus 43474 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus 43474 R-GGA-8878654 https://reactome.org/PathwayBrowser/#/R-GGA-8878654 ACP6 hydrolyses MYS-LPA IEA Gallus gallus 43474 R-GGA-8878787 https://reactome.org/PathwayBrowser/#/R-GGA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Gallus gallus 43474 R-GGA-8937767 https://reactome.org/PathwayBrowser/#/R-GGA-8937767 PTPN11 dephosphorylates RUNX1 IEA Gallus gallus 43474 R-GGA-8940070 https://reactome.org/PathwayBrowser/#/R-GGA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Gallus gallus 43474 R-GGA-8940074 https://reactome.org/PathwayBrowser/#/R-GGA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Gallus gallus 43474 R-GGA-8951498 https://reactome.org/PathwayBrowser/#/R-GGA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Gallus gallus 43474 R-GGA-8952137 https://reactome.org/PathwayBrowser/#/R-GGA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Gallus gallus 43474 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus 43474 R-GGA-8982020 https://reactome.org/PathwayBrowser/#/R-GGA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Gallus gallus 43474 R-GGA-8982021 https://reactome.org/PathwayBrowser/#/R-GGA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Gallus gallus 43474 R-GGA-8982025 https://reactome.org/PathwayBrowser/#/R-GGA-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Gallus gallus 43474 R-GGA-8985594 https://reactome.org/PathwayBrowser/#/R-GGA-8985594 MYO9B inactivates RHOA IEA Gallus gallus 43474 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus 43474 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus 43474 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus 43474 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus 43474 R-GGA-9013437 https://reactome.org/PathwayBrowser/#/R-GGA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Gallus gallus 43474 R-GGA-9014295 https://reactome.org/PathwayBrowser/#/R-GGA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Gallus gallus 43474 R-GGA-9014434 https://reactome.org/PathwayBrowser/#/R-GGA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Gallus gallus 43474 R-GGA-9017488 https://reactome.org/PathwayBrowser/#/R-GGA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Gallus gallus 43474 R-GGA-9018745 https://reactome.org/PathwayBrowser/#/R-GGA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Gallus gallus 43474 R-GGA-9018806 https://reactome.org/PathwayBrowser/#/R-GGA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Gallus gallus 43474 R-GGA-9018814 https://reactome.org/PathwayBrowser/#/R-GGA-9018814 RHOT1 hydrolyzes GTP IEA Gallus gallus 43474 R-GGA-9018826 https://reactome.org/PathwayBrowser/#/R-GGA-9018826 RHOT2 hydrolyzes GTP IEA Gallus gallus 43474 R-GGA-9038161 https://reactome.org/PathwayBrowser/#/R-GGA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Gallus gallus 43474 R-GGA-917693 https://reactome.org/PathwayBrowser/#/R-GGA-917693 ESCRT Disassembly IEA Gallus gallus 43474 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus 43474 R-GGA-936802 https://reactome.org/PathwayBrowser/#/R-GGA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Gallus gallus 43474 R-GGA-936883 https://reactome.org/PathwayBrowser/#/R-GGA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Gallus gallus 43474 R-GGA-936895 https://reactome.org/PathwayBrowser/#/R-GGA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Gallus gallus 43474 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 43474 R-GGA-937311 https://reactome.org/PathwayBrowser/#/R-GGA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Gallus gallus 43474 R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus 43474 R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus 43474 R-GGA-9624893 https://reactome.org/PathwayBrowser/#/R-GGA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Gallus gallus 43474 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus 43474 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus 43474 R-GGA-9658445 https://reactome.org/PathwayBrowser/#/R-GGA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Gallus gallus 43474 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 43474 R-GGA-9674816 https://reactome.org/PathwayBrowser/#/R-GGA-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Gallus gallus 43474 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus 43474 R-GGA-9693282 https://reactome.org/PathwayBrowser/#/R-GGA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Gallus gallus 43474 R-GGA-9700200 https://reactome.org/PathwayBrowser/#/R-GGA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Gallus gallus 43474 R-GGA-9706399 https://reactome.org/PathwayBrowser/#/R-GGA-9706399 RHOBTB3 hydrolyzes ATP IEA Gallus gallus 43474 R-GGA-9750546 https://reactome.org/PathwayBrowser/#/R-GGA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 43474 R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 43474 R-GGA-9750656 https://reactome.org/PathwayBrowser/#/R-GGA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Gallus gallus 43474 R-GGA-9753278 https://reactome.org/PathwayBrowser/#/R-GGA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 43474 R-GGA-9753283 https://reactome.org/PathwayBrowser/#/R-GGA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 43474 R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 43474 R-GGA-9759206 https://reactome.org/PathwayBrowser/#/R-GGA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Gallus gallus 43474 R-GGA-9759454 https://reactome.org/PathwayBrowser/#/R-GGA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Gallus gallus 43474 R-GGA-9759461 https://reactome.org/PathwayBrowser/#/R-GGA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Gallus gallus 43474 R-GGA-977324 https://reactome.org/PathwayBrowser/#/R-GGA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Gallus gallus 43474 R-GGA-9837419 https://reactome.org/PathwayBrowser/#/R-GGA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Gallus gallus 43474 R-GGA-9838004 https://reactome.org/PathwayBrowser/#/R-GGA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Gallus gallus 43474 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus 43474 R-GGA-9839059 https://reactome.org/PathwayBrowser/#/R-GGA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Gallus gallus 43474 R-GGA-9839105 https://reactome.org/PathwayBrowser/#/R-GGA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Gallus gallus 43474 R-GGA-9839113 https://reactome.org/PathwayBrowser/#/R-GGA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Gallus gallus 43474 R-GGA-9843721 https://reactome.org/PathwayBrowser/#/R-GGA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Gallus gallus 43474 R-GGA-9853385 https://reactome.org/PathwayBrowser/#/R-GGA-9853385 PPP1CC dephosphorylates PLK1 IEA Gallus gallus 43474 R-GGA-9861725 https://reactome.org/PathwayBrowser/#/R-GGA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Gallus gallus 43474 R-GGA-997309 https://reactome.org/PathwayBrowser/#/R-GGA-997309 Dephosphorylation of STAT1 by SHP2 IEA Gallus gallus 43474 R-GGA-997311 https://reactome.org/PathwayBrowser/#/R-GGA-997311 Dephosphorylation of TYK2 by PTP1B IEA Gallus gallus 43474 R-GGA-997314 https://reactome.org/PathwayBrowser/#/R-GGA-997314 Dephosphorylation of JAK1 by SHP1 IEA Gallus gallus 43474 R-GGA-997326 https://reactome.org/PathwayBrowser/#/R-GGA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Gallus gallus 43474 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 43474 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 43474 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 43474 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 43474 R-HSA-109415 https://reactome.org/PathwayBrowser/#/R-HSA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] TAS Homo sapiens 43474 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 43474 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 43474 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 43474 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 43474 R-HSA-111215 https://reactome.org/PathwayBrowser/#/R-HSA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate TAS Homo sapiens 43474 R-HSA-111524 https://reactome.org/PathwayBrowser/#/R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] TAS Homo sapiens 43474 R-HSA-112033 https://reactome.org/PathwayBrowser/#/R-HSA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine TAS Homo sapiens 43474 R-HSA-112034 https://reactome.org/PathwayBrowser/#/R-HSA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine TAS Homo sapiens 43474 R-HSA-112037 https://reactome.org/PathwayBrowser/#/R-HSA-112037 Inactivation of PLC beta TAS Homo sapiens 43474 R-HSA-112265 https://reactome.org/PathwayBrowser/#/R-HSA-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] TAS Homo sapiens 43474 R-HSA-112266 https://reactome.org/PathwayBrowser/#/R-HSA-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] TAS Homo sapiens 43474 R-HSA-113503 https://reactome.org/PathwayBrowser/#/R-HSA-113503 PP2A mediated localization of RB1 protein in chromatin TAS Homo sapiens 43474 R-HSA-1169188 https://reactome.org/PathwayBrowser/#/R-HSA-1169188 SHP1 (PTPN6) dephosphorylates JAK2 IEA Homo sapiens 43474 R-HSA-1169192 https://reactome.org/PathwayBrowser/#/R-HSA-1169192 PTP1B dephosphorylates GHR TAS Homo sapiens 43474 R-HSA-1169210 https://reactome.org/PathwayBrowser/#/R-HSA-1169210 PTP1B dephosphorylates JAK2 IEA Homo sapiens 43474 R-HSA-1236949 https://reactome.org/PathwayBrowser/#/R-HSA-1236949 Translocation of antigenic peptides back to phagosomes via TAP IEA Homo sapiens 43474 R-HSA-1237129 https://reactome.org/PathwayBrowser/#/R-HSA-1237129 Acireductone is created TAS Homo sapiens 43474 R-HSA-1237160 https://reactome.org/PathwayBrowser/#/R-HSA-1237160 MTA is cleaved and phosphorylated TAS Homo sapiens 43474 R-HSA-1247935 https://reactome.org/PathwayBrowser/#/R-HSA-1247935 OPLAH hydrolyses OPRO to L-Glu TAS Homo sapiens 43474 R-HSA-1295632 https://reactome.org/PathwayBrowser/#/R-HSA-1295632 PPA2A dephosphorylates SPRY2 TAS Homo sapiens 43474 R-HSA-1299475 https://reactome.org/PathwayBrowser/#/R-HSA-1299475 TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix IEA Homo sapiens 43474 R-HSA-1363274 https://reactome.org/PathwayBrowser/#/R-HSA-1363274 Dephosphorylation of p107 (RBL1) by PP2A TAS Homo sapiens 43474 R-HSA-1363276 https://reactome.org/PathwayBrowser/#/R-HSA-1363276 Dephosphorylation of p130 (RBL2) by PP2A TAS Homo sapiens 43474 R-HSA-1369028 https://reactome.org/PathwayBrowser/#/R-HSA-1369028 ABCAs mediate lipid efflux TAS Homo sapiens 43474 R-HSA-1369052 https://reactome.org/PathwayBrowser/#/R-HSA-1369052 ABCAs mediate lipid influx TAS Homo sapiens 43474 R-HSA-1369065 https://reactome.org/PathwayBrowser/#/R-HSA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix TAS Homo sapiens 43474 R-HSA-139906 https://reactome.org/PathwayBrowser/#/R-HSA-139906 Activation of BAD by calcineurin TAS Homo sapiens 43474 R-HSA-141673 https://reactome.org/PathwayBrowser/#/R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex IEA Homo sapiens 43474 R-HSA-1454916 https://reactome.org/PathwayBrowser/#/R-HSA-1454916 The ABCC family mediates organic anion transport TAS Homo sapiens 43474 R-HSA-1454928 https://reactome.org/PathwayBrowser/#/R-HSA-1454928 ABCG4 may mediate cholesterol efflux TAS Homo sapiens 43474 R-HSA-1458485 https://reactome.org/PathwayBrowser/#/R-HSA-1458485 RALA hydrolyzes GTP IEA Homo sapiens 43474 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-1467466 https://reactome.org/PathwayBrowser/#/R-HSA-1467466 ABCA4 mediates atRAL transport TAS Homo sapiens 43474 R-HSA-1483096 https://reactome.org/PathwayBrowser/#/R-HSA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 TAS Homo sapiens 43474 R-HSA-1483159 https://reactome.org/PathwayBrowser/#/R-HSA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 TAS Homo sapiens 43474 R-HSA-1483197 https://reactome.org/PathwayBrowser/#/R-HSA-1483197 PTPMT1 dephosphorylates PGP to PG IEA Homo sapiens 43474 R-HSA-1483203 https://reactome.org/PathwayBrowser/#/R-HSA-1483203 PA is dephosphorylated to DAG by LPIN TAS Homo sapiens 43474 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 43474 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 43474 R-HSA-159101 https://reactome.org/PathwayBrowser/#/R-HSA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) TAS Homo sapiens 43474 R-HSA-163120 https://reactome.org/PathwayBrowser/#/R-HSA-163120 Disassociation of Telomerase RNP and the Chromosome End TAS Homo sapiens 43474 R-HSA-163489 https://reactome.org/PathwayBrowser/#/R-HSA-163489 phosphorylated HSL + H2O -> HSL + orthophosphate IEA Homo sapiens 43474 R-HSA-163568 https://reactome.org/PathwayBrowser/#/R-HSA-163568 phosphorylated perilipin + H2O -> perilipin + orthophosphate IEA Homo sapiens 43474 R-HSA-163688 https://reactome.org/PathwayBrowser/#/R-HSA-163688 Dephosphorylation of pChREBP (Thr 666) by PP2A IEA Homo sapiens 43474 R-HSA-163689 https://reactome.org/PathwayBrowser/#/R-HSA-163689 Dephosphorylation of pChREBP (Ser 196) by PP2A IEA Homo sapiens 43474 R-HSA-163750 https://reactome.org/PathwayBrowser/#/R-HSA-163750 Dephosphorylation of phosphoPFKFB1 by PP2A complex IEA Homo sapiens 43474 R-HSA-1638821 https://reactome.org/PathwayBrowser/#/R-HSA-1638821 PP2A-B56 dephosphorylates centromeric cohesin TAS Homo sapiens 43474 R-HSA-164056 https://reactome.org/PathwayBrowser/#/R-HSA-164056 Dephosphorylation of pChREBP (Ser 556) by PP2A IEA Homo sapiens 43474 R-HSA-164381 https://reactome.org/PathwayBrowser/#/R-HSA-164381 G alpha (s) auto-inactivates by hydrolysing GTP to GDP TAS Homo sapiens 43474 R-HSA-164832 https://reactome.org/PathwayBrowser/#/R-HSA-164832 ATPase synthesizes ATP TAS Homo sapiens 43474 R-HSA-164840 https://reactome.org/PathwayBrowser/#/R-HSA-164840 ADP and Pi bind to ATPase TAS Homo sapiens 43474 R-HSA-165055 https://reactome.org/PathwayBrowser/#/R-HSA-165055 Hydrolysis of Ran:GTP to Ran:GDP TAS Homo sapiens 43474 R-HSA-167097 https://reactome.org/PathwayBrowser/#/R-HSA-167097 HIV Promoter Opening: First Transition IEA Homo sapiens 43474 R-HSA-1675795 https://reactome.org/PathwayBrowser/#/R-HSA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane TAS Homo sapiens 43474 R-HSA-1675824 https://reactome.org/PathwayBrowser/#/R-HSA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane TAS Homo sapiens 43474 R-HSA-1675836 https://reactome.org/PathwayBrowser/#/R-HSA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane TAS Homo sapiens 43474 R-HSA-1675949 https://reactome.org/PathwayBrowser/#/R-HSA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane TAS Homo sapiens 43474 R-HSA-1675988 https://reactome.org/PathwayBrowser/#/R-HSA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane TAS Homo sapiens 43474 R-HSA-1675994 https://reactome.org/PathwayBrowser/#/R-HSA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane TAS Homo sapiens 43474 R-HSA-1676005 https://reactome.org/PathwayBrowser/#/R-HSA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane TAS Homo sapiens 43474 R-HSA-1676020 https://reactome.org/PathwayBrowser/#/R-HSA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane TAS Homo sapiens 43474 R-HSA-1676065 https://reactome.org/PathwayBrowser/#/R-HSA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane TAS Homo sapiens 43474 R-HSA-1676105 https://reactome.org/PathwayBrowser/#/R-HSA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane TAS Homo sapiens 43474 R-HSA-1676114 https://reactome.org/PathwayBrowser/#/R-HSA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane TAS Homo sapiens 43474 R-HSA-1676124 https://reactome.org/PathwayBrowser/#/R-HSA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane TAS Homo sapiens 43474 R-HSA-1676133 https://reactome.org/PathwayBrowser/#/R-HSA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane TAS Homo sapiens 43474 R-HSA-1676141 https://reactome.org/PathwayBrowser/#/R-HSA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane TAS Homo sapiens 43474 R-HSA-1676149 https://reactome.org/PathwayBrowser/#/R-HSA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane TAS Homo sapiens 43474 R-HSA-1676162 https://reactome.org/PathwayBrowser/#/R-HSA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane TAS Homo sapiens 43474 R-HSA-1676164 https://reactome.org/PathwayBrowser/#/R-HSA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane TAS Homo sapiens 43474 R-HSA-1676174 https://reactome.org/PathwayBrowser/#/R-HSA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane TAS Homo sapiens 43474 R-HSA-1676177 https://reactome.org/PathwayBrowser/#/R-HSA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane TAS Homo sapiens 43474 R-HSA-1676203 https://reactome.org/PathwayBrowser/#/R-HSA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane TAS Homo sapiens 43474 R-HSA-1676204 https://reactome.org/PathwayBrowser/#/R-HSA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane TAS Homo sapiens 43474 R-HSA-168880 https://reactome.org/PathwayBrowser/#/R-HSA-168880 vRNP Export through the nuclear pore TAS Homo sapiens 43474 R-HSA-170153 https://reactome.org/PathwayBrowser/#/R-HSA-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases TAS Homo sapiens 43474 R-HSA-170158 https://reactome.org/PathwayBrowser/#/R-HSA-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes TAS Homo sapiens 43474 R-HSA-170161 https://reactome.org/PathwayBrowser/#/R-HSA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B TAS Homo sapiens 43474 R-HSA-170666 https://reactome.org/PathwayBrowser/#/R-HSA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf TAS Homo sapiens 43474 R-HSA-170685 https://reactome.org/PathwayBrowser/#/R-HSA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf TAS Homo sapiens 43474 R-HSA-170686 https://reactome.org/PathwayBrowser/#/R-HSA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha TAS Homo sapiens 43474 R-HSA-174110 https://reactome.org/PathwayBrowser/#/R-HSA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 TAS Homo sapiens 43474 R-HSA-174367 https://reactome.org/PathwayBrowser/#/R-HSA-174367 GCL ligates L-Glu to L-Cys TAS Homo sapiens 43474 R-HSA-174391 https://reactome.org/PathwayBrowser/#/R-HSA-174391 MAT1A multimers transfer Ado from ATP to L-Met TAS Homo sapiens 43474 R-HSA-174394 https://reactome.org/PathwayBrowser/#/R-HSA-174394 GSS:Mg2+ dimer synthesizes GSH TAS Homo sapiens 43474 R-HSA-174438 https://reactome.org/PathwayBrowser/#/R-HSA-174438 Formation of the Flap Intermediate on the C-strand TAS Homo sapiens 43474 R-HSA-174439 https://reactome.org/PathwayBrowser/#/R-HSA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere TAS Homo sapiens 43474 R-HSA-176606 https://reactome.org/PathwayBrowser/#/R-HSA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate TAS Homo sapiens 43474 R-HSA-177501 https://reactome.org/PathwayBrowser/#/R-HSA-177501 Endocytosis (internalization) of clathrin-coated vesicle IEA Homo sapiens 43474 R-HSA-177923 https://reactome.org/PathwayBrowser/#/R-HSA-177923 Sustained activation of SRC kinase by SHP2 TAS Homo sapiens 43474 R-HSA-177924 https://reactome.org/PathwayBrowser/#/R-HSA-177924 Dephosphorylation of Gab1 by SHP2 TAS Homo sapiens 43474 R-HSA-177926 https://reactome.org/PathwayBrowser/#/R-HSA-177926 Dephosphorylation of PAG by SHP2 TAS Homo sapiens 43474 R-HSA-177935 https://reactome.org/PathwayBrowser/#/R-HSA-177935 SHP2 dephosphorylates Tyr 992 on EGFR TAS Homo sapiens 43474 R-HSA-178178 https://reactome.org/PathwayBrowser/#/R-HSA-178178 PP1 dephosphorylates TGFBR1 IEA Homo sapiens 43474 R-HSA-1855154 https://reactome.org/PathwayBrowser/#/R-HSA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 43474 R-HSA-1855159 https://reactome.org/PathwayBrowser/#/R-HSA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol TAS Homo sapiens 43474 R-HSA-1855163 https://reactome.org/PathwayBrowser/#/R-HSA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen TAS Homo sapiens 43474 R-HSA-1855165 https://reactome.org/PathwayBrowser/#/R-HSA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 43474 R-HSA-1855166 https://reactome.org/PathwayBrowser/#/R-HSA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol TAS Homo sapiens 43474 R-HSA-1855171 https://reactome.org/PathwayBrowser/#/R-HSA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol TAS Homo sapiens 43474 R-HSA-1855174 https://reactome.org/PathwayBrowser/#/R-HSA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol TAS Homo sapiens 43474 R-HSA-1855180 https://reactome.org/PathwayBrowser/#/R-HSA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol TAS Homo sapiens 43474 R-HSA-1855198 https://reactome.org/PathwayBrowser/#/R-HSA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 43474 R-HSA-1855200 https://reactome.org/PathwayBrowser/#/R-HSA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen TAS Homo sapiens 43474 R-HSA-1855202 https://reactome.org/PathwayBrowser/#/R-HSA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol TAS Homo sapiens 43474 R-HSA-1855205 https://reactome.org/PathwayBrowser/#/R-HSA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol TAS Homo sapiens 43474 R-HSA-1855208 https://reactome.org/PathwayBrowser/#/R-HSA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol TAS Homo sapiens 43474 R-HSA-1855210 https://reactome.org/PathwayBrowser/#/R-HSA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 43474 R-HSA-1855211 https://reactome.org/PathwayBrowser/#/R-HSA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 43474 R-HSA-1855213 https://reactome.org/PathwayBrowser/#/R-HSA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane TAS Homo sapiens 43474 R-HSA-1855218 https://reactome.org/PathwayBrowser/#/R-HSA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol TAS Homo sapiens 43474 R-HSA-1855219 https://reactome.org/PathwayBrowser/#/R-HSA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 43474 R-HSA-1855222 https://reactome.org/PathwayBrowser/#/R-HSA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane TAS Homo sapiens 43474 R-HSA-1855225 https://reactome.org/PathwayBrowser/#/R-HSA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen TAS Homo sapiens 43474 R-HSA-1855232 https://reactome.org/PathwayBrowser/#/R-HSA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol TAS Homo sapiens 43474 R-HSA-1861595 https://reactome.org/PathwayBrowser/#/R-HSA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner TAS Homo sapiens 43474 R-HSA-191414 https://reactome.org/PathwayBrowser/#/R-HSA-191414 MVD decarboxylates MVA5PP to IPPP TAS Homo sapiens 43474 R-HSA-193362 https://reactome.org/PathwayBrowser/#/R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-194153 https://reactome.org/PathwayBrowser/#/R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-196950 https://reactome.org/PathwayBrowser/#/R-HSA-196950 2xTRAP hydrolyzes FMN to RIB TAS Homo sapiens 43474 R-HSA-197958 https://reactome.org/PathwayBrowser/#/R-HSA-197958 FPGS-2 transforms THF to THFPG TAS Homo sapiens 43474 R-HSA-198513 https://reactome.org/PathwayBrowser/#/R-HSA-198513 SLC7A4 exchanges G6P for Pi across the ER membrane TAS Homo sapiens 43474 R-HSA-199425 https://reactome.org/PathwayBrowser/#/R-HSA-199425 PHLPP dephosphorylates S473 in AKT TAS Homo sapiens 43474 R-HSA-199456 https://reactome.org/PathwayBrowser/#/R-HSA-199456 PTEN dephosphorylates PIP3 TAS Homo sapiens 43474 R-HSA-199959 https://reactome.org/PathwayBrowser/#/R-HSA-199959 ERKs are inactivated by protein phosphatase 2A TAS Homo sapiens 43474 R-HSA-200555 https://reactome.org/PathwayBrowser/#/R-HSA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate TAS Homo sapiens 43474 R-HSA-200681 https://reactome.org/PathwayBrowser/#/R-HSA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG TAS Homo sapiens 43474 R-HSA-200682 https://reactome.org/PathwayBrowser/#/R-HSA-200682 Mitochondrial FPGS-1 transforms THF to THFPG TAS Homo sapiens 43474 R-HSA-200711 https://reactome.org/PathwayBrowser/#/R-HSA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG TAS Homo sapiens 43474 R-HSA-201787 https://reactome.org/PathwayBrowser/#/R-HSA-201787 PPP3 complex dephosphorylates DARPP-32 on Thr34 IEA Homo sapiens 43474 R-HSA-201790 https://reactome.org/PathwayBrowser/#/R-HSA-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A TAS Homo sapiens 43474 R-HSA-202214 https://reactome.org/PathwayBrowser/#/R-HSA-202214 Dephosphorylation of Lck-pY505 by CD45 TAS Homo sapiens 43474 R-HSA-202237 https://reactome.org/PathwayBrowser/#/R-HSA-202237 Hydrolysis of PIP3 to PI(3,4)P2 TAS Homo sapiens 43474 R-HSA-2023971 https://reactome.org/PathwayBrowser/#/R-HSA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 43474 R-HSA-2023973 https://reactome.org/PathwayBrowser/#/R-HSA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 43474 R-HSA-2029468 https://reactome.org/PathwayBrowser/#/R-HSA-2029468 Conversion of PA into DAG by PAP-1 TAS Homo sapiens 43474 R-HSA-2029476 https://reactome.org/PathwayBrowser/#/R-HSA-2029476 Role of myosins in phagosome formation TAS Homo sapiens 43474 R-HSA-203797 https://reactome.org/PathwayBrowser/#/R-HSA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) TAS Homo sapiens 43474 R-HSA-203906 https://reactome.org/PathwayBrowser/#/R-HSA-203906 Exportin complex translocates pre-miRNA to cytosol TAS Homo sapiens 43474 R-HSA-203973 https://reactome.org/PathwayBrowser/#/R-HSA-203973 Vesicle budding TAS Homo sapiens 43474 R-HSA-204169 https://reactome.org/PathwayBrowser/#/R-HSA-204169 PDP1,2 dephosphorylate p-lipo-PDH TAS Homo sapiens 43474 R-HSA-2046093 https://reactome.org/PathwayBrowser/#/R-HSA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes TAS Homo sapiens 43474 R-HSA-209055 https://reactome.org/PathwayBrowser/#/R-HSA-209055 PPM1A dephosphorylates nuclear SMAD2/3 TAS Homo sapiens 43474 R-HSA-2130641 https://reactome.org/PathwayBrowser/#/R-HSA-2130641 Translocation of TGN-lysosome vesicle to lysosome TAS Homo sapiens 43474 R-HSA-2130725 https://reactome.org/PathwayBrowser/#/R-HSA-2130725 Internalization of MHC II:Ii clathrin coated vesicle TAS Homo sapiens 43474 R-HSA-2161506 https://reactome.org/PathwayBrowser/#/R-HSA-2161506 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 43474 R-HSA-2161538 https://reactome.org/PathwayBrowser/#/R-HSA-2161538 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 43474 R-HSA-216723 https://reactome.org/PathwayBrowser/#/R-HSA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 43474 R-HSA-216757 https://reactome.org/PathwayBrowser/#/R-HSA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane TAS Homo sapiens 43474 R-HSA-2187401 https://reactome.org/PathwayBrowser/#/R-HSA-2187401 MTMR4 dephosphorylates SMAD2/3 TAS Homo sapiens 43474 R-HSA-2395873 https://reactome.org/PathwayBrowser/#/R-HSA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP TAS Homo sapiens 43474 R-HSA-2395876 https://reactome.org/PathwayBrowser/#/R-HSA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 43474 R-HSA-2395879 https://reactome.org/PathwayBrowser/#/R-HSA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 43474 R-HSA-2395965 https://reactome.org/PathwayBrowser/#/R-HSA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP TAS Homo sapiens 43474 R-HSA-2408551 https://reactome.org/PathwayBrowser/#/R-HSA-2408551 SeMet is converted to AdoSeMet by MAT TAS Homo sapiens 43474 R-HSA-2408555 https://reactome.org/PathwayBrowser/#/R-HSA-2408555 Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer TAS Homo sapiens 43474 R-HSA-2466749 https://reactome.org/PathwayBrowser/#/R-HSA-2466749 ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol IEA Homo sapiens 43474 R-HSA-2509793 https://reactome.org/PathwayBrowser/#/R-HSA-2509793 NUDT16 hydrolyses dIDP to dIMP TAS Homo sapiens 43474 R-HSA-2509816 https://reactome.org/PathwayBrowser/#/R-HSA-2509816 NUDT16 hydrolyses IDP to IMP TAS Homo sapiens 43474 R-HSA-2529015 https://reactome.org/PathwayBrowser/#/R-HSA-2529015 Dephosphorylation of CK2-modified condensin I TAS Homo sapiens 43474 R-HSA-2584246 https://reactome.org/PathwayBrowser/#/R-HSA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP TAS Homo sapiens 43474 R-HSA-265783 https://reactome.org/PathwayBrowser/#/R-HSA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-266082 https://reactome.org/PathwayBrowser/#/R-HSA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface TAS Homo sapiens 43474 R-HSA-2682349 https://reactome.org/PathwayBrowser/#/R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels TAS Homo sapiens 43474 R-HSA-2730849 https://reactome.org/PathwayBrowser/#/R-HSA-2730849 Calcineurin binds and dephosphorylates NFAT TAS Homo sapiens 43474 R-HSA-2872498 https://reactome.org/PathwayBrowser/#/R-HSA-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol TAS Homo sapiens 43474 R-HSA-2995388 https://reactome.org/PathwayBrowser/#/R-HSA-2995388 PP2A dephosphorylates BANF1 TAS Homo sapiens 43474 R-HSA-3002811 https://reactome.org/PathwayBrowser/#/R-HSA-3002811 Myosin phosphatase dephosphorylates PLK1 TAS Homo sapiens 43474 R-HSA-3095901 https://reactome.org/PathwayBrowser/#/R-HSA-3095901 ABCC1 transports cytosolic RCbl to extracellular region TAS Homo sapiens 43474 R-HSA-3229118 https://reactome.org/PathwayBrowser/#/R-HSA-3229118 Defective SLC37A4 does not exchange G6P and Pi across the ER membrane TAS Homo sapiens 43474 R-HSA-3257122 https://reactome.org/PathwayBrowser/#/R-HSA-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane TAS Homo sapiens 43474 R-HSA-3262512 https://reactome.org/PathwayBrowser/#/R-HSA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) TAS Homo sapiens 43474 R-HSA-3266566 https://reactome.org/PathwayBrowser/#/R-HSA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) TAS Homo sapiens 43474 R-HSA-3371422 https://reactome.org/PathwayBrowser/#/R-HSA-3371422 ATP hydrolysis by HSP70 TAS Homo sapiens 43474 R-HSA-3697838 https://reactome.org/PathwayBrowser/#/R-HSA-3697838 ATP7A transfers Cu from ATOX1 to SOD3 IEA Homo sapiens 43474 R-HSA-372843 https://reactome.org/PathwayBrowser/#/R-HSA-372843 SLC25A10 mediates exchange of malate and phosphate TAS Homo sapiens 43474 R-HSA-374916 https://reactome.org/PathwayBrowser/#/R-HSA-374916 Re-acidification of clathrin sculpted monoamine transport vesicle lumen TAS Homo sapiens 43474 R-HSA-377643 https://reactome.org/PathwayBrowser/#/R-HSA-377643 Dephosphorylation of inactive SRC by PTPB1 TAS Homo sapiens 43474 R-HSA-3781011 https://reactome.org/PathwayBrowser/#/R-HSA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 TAS Homo sapiens 43474 R-HSA-3781018 https://reactome.org/PathwayBrowser/#/R-HSA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 TAS Homo sapiens 43474 R-HSA-380949 https://reactome.org/PathwayBrowser/#/R-HSA-380949 AMPK is dephosphorylated TAS Homo sapiens 43474 R-HSA-380979 https://reactome.org/PathwayBrowser/#/R-HSA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP TAS Homo sapiens 43474 R-HSA-382553 https://reactome.org/PathwayBrowser/#/R-HSA-382553 ABCA7:Apo1A-mediated phospholipid efflux TAS Homo sapiens 43474 R-HSA-382560 https://reactome.org/PathwayBrowser/#/R-HSA-382560 ABC7, mABC1 and mABC2 mediate heme transport TAS Homo sapiens 43474 R-HSA-382575 https://reactome.org/PathwayBrowser/#/R-HSA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix TAS Homo sapiens 43474 R-HSA-383190 https://reactome.org/PathwayBrowser/#/R-HSA-383190 HCO3- transport through ion channel TAS Homo sapiens 43474 R-HSA-389954 https://reactome.org/PathwayBrowser/#/R-HSA-389954 Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC IEA Homo sapiens 43474 R-HSA-389974 https://reactome.org/PathwayBrowser/#/R-HSA-389974 Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E:Cofactor C-> Beta-tubulin:GDP :alpha-tubulin:GTP heterodimer +Cofactor E+ Cofactor D+ Cofactor C+ Pi IEA Homo sapiens 43474 R-HSA-390329 https://reactome.org/PathwayBrowser/#/R-HSA-390329 Dephosphorylation of AKT by PP2A TAS Homo sapiens 43474 R-HSA-390453 https://reactome.org/PathwayBrowser/#/R-HSA-390453 Hydrolysis of ATP and release of folded actin from CCT/TriC IEA Homo sapiens 43474 R-HSA-390593 https://reactome.org/PathwayBrowser/#/R-HSA-390593 ATP Hydrolysis By Myosin TAS Homo sapiens 43474 R-HSA-391868 https://reactome.org/PathwayBrowser/#/R-HSA-391868 Dephosphorylation of NCAM1 bound pFyn IEA Homo sapiens 43474 R-HSA-392212 https://reactome.org/PathwayBrowser/#/R-HSA-392212 G alpha (i) auto-inactivates by hydrolysing GTP to GDP IEA Homo sapiens 43474 R-HSA-399935 https://reactome.org/PathwayBrowser/#/R-HSA-399935 Inactivation of R-Ras by Sema3A-Plexin-A GAP activity IEA Homo sapiens 43474 R-HSA-4084976 https://reactome.org/PathwayBrowser/#/R-HSA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P TAS Homo sapiens 43474 R-HSA-4084989 https://reactome.org/PathwayBrowser/#/R-HSA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac TAS Homo sapiens 43474 R-HSA-4088141 https://reactome.org/PathwayBrowser/#/R-HSA-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 TAS Homo sapiens 43474 R-HSA-4093339 https://reactome.org/PathwayBrowser/#/R-HSA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it TAS Homo sapiens 43474 R-HSA-416320 https://reactome.org/PathwayBrowser/#/R-HSA-416320 Trafficking of GluR1-containing AMPA receptors TAS Homo sapiens 43474 R-HSA-416546 https://reactome.org/PathwayBrowser/#/R-HSA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity TAS Homo sapiens 43474 R-HSA-416559 https://reactome.org/PathwayBrowser/#/R-HSA-416559 Inactivation of Rho-GTP by p190RhoGAP TAS Homo sapiens 43474 R-HSA-416639 https://reactome.org/PathwayBrowser/#/R-HSA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites TAS Homo sapiens 43474 R-HSA-416985 https://reactome.org/PathwayBrowser/#/R-HSA-416985 Trafficking of GluR2-containing AMPA receptors to synapse TAS Homo sapiens 43474 R-HSA-419232 https://reactome.org/PathwayBrowser/#/R-HSA-419232 Myosin phosphatase dephosphorylates myosin regulatory light chain IEA Homo sapiens 43474 R-HSA-421007 https://reactome.org/PathwayBrowser/#/R-HSA-421007 Endocytosis of Ca impermeable AMPA receptors TAS Homo sapiens 43474 R-HSA-421831 https://reactome.org/PathwayBrowser/#/R-HSA-421831 trans-Golgi Network Coat Assembly TAS Homo sapiens 43474 R-HSA-421835 https://reactome.org/PathwayBrowser/#/R-HSA-421835 trans-Golgi Network Vesicle Scission TAS Homo sapiens 43474 R-HSA-421836 https://reactome.org/PathwayBrowser/#/R-HSA-421836 trans-Golgi Network Derived Vesicle Uncoating TAS Homo sapiens 43474 R-HSA-427605 https://reactome.org/PathwayBrowser/#/R-HSA-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol TAS Homo sapiens 43474 R-HSA-427645 https://reactome.org/PathwayBrowser/#/R-HSA-427645 SLC34A3 cotransports Pi, 2Na+ TAS Homo sapiens 43474 R-HSA-427656 https://reactome.org/PathwayBrowser/#/R-HSA-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol TAS Homo sapiens 43474 R-HSA-428522 https://reactome.org/PathwayBrowser/#/R-HSA-428522 Inactivation of RAC1 IEA Homo sapiens 43474 R-HSA-428533 https://reactome.org/PathwayBrowser/#/R-HSA-428533 Inactivation of CDC42 IEA Homo sapiens 43474 R-HSA-428609 https://reactome.org/PathwayBrowser/#/R-HSA-428609 Type I Na+-coupled phosphate co-transport TAS Homo sapiens 43474 R-HSA-428664 https://reactome.org/PathwayBrowser/#/R-HSA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates TAS Homo sapiens 43474 R-HSA-428690 https://reactome.org/PathwayBrowser/#/R-HSA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate TAS Homo sapiens 43474 R-HSA-428696 https://reactome.org/PathwayBrowser/#/R-HSA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate TAS Homo sapiens 43474 R-HSA-429157 https://reactome.org/PathwayBrowser/#/R-HSA-429157 ABCC4 accumulation of dense granule contents TAS Homo sapiens 43474 R-HSA-429730 https://reactome.org/PathwayBrowser/#/R-HSA-429730 PPM1L dephosphorylates multiphospho-CERT1-2 TAS Homo sapiens 43474 R-HSA-432688 https://reactome.org/PathwayBrowser/#/R-HSA-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating TAS Homo sapiens 43474 R-HSA-432706 https://reactome.org/PathwayBrowser/#/R-HSA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly TAS Homo sapiens 43474 R-HSA-432707 https://reactome.org/PathwayBrowser/#/R-HSA-432707 trans-Golgi Network Lysosomal Vesicle Scission TAS Homo sapiens 43474 R-HSA-4419948 https://reactome.org/PathwayBrowser/#/R-HSA-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN TAS Homo sapiens 43474 R-HSA-445089 https://reactome.org/PathwayBrowser/#/R-HSA-445089 Dephosphorylation of pL1 (Y1176) TAS Homo sapiens 43474 R-HSA-445699 https://reactome.org/PathwayBrowser/#/R-HSA-445699 ATP Hydrolysis By Myosin TAS Homo sapiens 43474 R-HSA-446200 https://reactome.org/PathwayBrowser/#/R-HSA-446200 DOLPP1 dephosphorylates DOLDP to DOLP TAS Homo sapiens 43474 R-HSA-449937 https://reactome.org/PathwayBrowser/#/R-HSA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] TAS Homo sapiens 43474 R-HSA-453339 https://reactome.org/PathwayBrowser/#/R-HSA-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] TAS Homo sapiens 43474 R-HSA-453358 https://reactome.org/PathwayBrowser/#/R-HSA-453358 poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] IEA Homo sapiens 43474 R-HSA-4551451 https://reactome.org/PathwayBrowser/#/R-HSA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling TAS Homo sapiens 43474 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 43474 R-HSA-504054 https://reactome.org/PathwayBrowser/#/R-HSA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] TAS Homo sapiens 43474 R-HSA-508040 https://reactome.org/PathwayBrowser/#/R-HSA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] TAS Homo sapiens 43474 R-HSA-508308 https://reactome.org/PathwayBrowser/#/R-HSA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] TAS Homo sapiens 43474 R-HSA-5221130 https://reactome.org/PathwayBrowser/#/R-HSA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol TAS Homo sapiens 43474 R-HSA-5223313 https://reactome.org/PathwayBrowser/#/R-HSA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) TAS Homo sapiens 43474 R-HSA-5223317 https://reactome.org/PathwayBrowser/#/R-HSA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen TAS Homo sapiens 43474 R-HSA-5251955 https://reactome.org/PathwayBrowser/#/R-HSA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm TAS Homo sapiens 43474 R-HSA-5251959 https://reactome.org/PathwayBrowser/#/R-HSA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol TAS Homo sapiens 43474 R-HSA-5251989 https://reactome.org/PathwayBrowser/#/R-HSA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol TAS Homo sapiens 43474 R-HSA-5333615 https://reactome.org/PathwayBrowser/#/R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC IEA Homo sapiens 43474 R-HSA-5389839 https://reactome.org/PathwayBrowser/#/R-HSA-5389839 39S subunit binds 28S subunit:mRNA:fMet-tRNA IEA Homo sapiens 43474 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 43474 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 43474 R-HSA-5419273 https://reactome.org/PathwayBrowser/#/R-HSA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits TAS Homo sapiens 43474 R-HSA-5419279 https://reactome.org/PathwayBrowser/#/R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) IEA Homo sapiens 43474 R-HSA-555065 https://reactome.org/PathwayBrowser/#/R-HSA-555065 Formation of clathrin coated vesicle TAS Homo sapiens 43474 R-HSA-5603114 https://reactome.org/PathwayBrowser/#/R-HSA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met TAS Homo sapiens 43474 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 43474 R-HSA-5623513 https://reactome.org/PathwayBrowser/#/R-HSA-5623513 ASAP1 stimulates GTPase activity of ARF4 TAS Homo sapiens 43474 R-HSA-5625123 https://reactome.org/PathwayBrowser/#/R-HSA-5625123 Defective SLC20A2 does not cotransport Pi, Na+ from extracellular region to cytosol TAS Homo sapiens 43474 R-HSA-5628905 https://reactome.org/PathwayBrowser/#/R-HSA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate TAS Homo sapiens 43474 R-HSA-5649705 https://reactome.org/PathwayBrowser/#/R-HSA-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) TAS Homo sapiens 43474 R-HSA-5651685 https://reactome.org/PathwayBrowser/#/R-HSA-5651685 Defective SLC34A1 does not cotransport Pi, 3Na+ TAS Homo sapiens 43474 R-HSA-5651697 https://reactome.org/PathwayBrowser/#/R-HSA-5651697 Defective SLC34A2 does not cotransport Pi, 3Na+ TAS Homo sapiens 43474 R-HSA-5651971 https://reactome.org/PathwayBrowser/#/R-HSA-5651971 Defective SLC34A3 does not cotransport Pi, 2Na+ TAS Homo sapiens 43474 R-HSA-5665809 https://reactome.org/PathwayBrowser/#/R-HSA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments TAS Homo sapiens 43474 R-HSA-5672957 https://reactome.org/PathwayBrowser/#/R-HSA-5672957 PP2A dephosphorylates KSR1 TAS Homo sapiens 43474 R-HSA-5672961 https://reactome.org/PathwayBrowser/#/R-HSA-5672961 PP2A dephosphorylates inactive RAFs TAS Homo sapiens 43474 R-HSA-5675373 https://reactome.org/PathwayBrowser/#/R-HSA-5675373 Nuclear DUSPs dephosphorylate MAPKs TAS Homo sapiens 43474 R-HSA-5675376 https://reactome.org/PathwayBrowser/#/R-HSA-5675376 Cytosolic DUSPs dephosphorylate MAPKs TAS Homo sapiens 43474 R-HSA-5675431 https://reactome.org/PathwayBrowser/#/R-HSA-5675431 PP2A dephosphorylates RAF1 TAS Homo sapiens 43474 R-HSA-5675433 https://reactome.org/PathwayBrowser/#/R-HSA-5675433 PP5 dephosphorylates RAF1 S338 TAS Homo sapiens 43474 R-HSA-5678706 https://reactome.org/PathwayBrowser/#/R-HSA-5678706 ABCB4 transports PC from plasma membrane to extracellular region TAS Homo sapiens 43474 R-HSA-5678863 https://reactome.org/PathwayBrowser/#/R-HSA-5678863 CFTR transports Cl- from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-5678992 https://reactome.org/PathwayBrowser/#/R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-5679041 https://reactome.org/PathwayBrowser/#/R-HSA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-5682285 https://reactome.org/PathwayBrowser/#/R-HSA-5682285 ABCA12 transports lipids from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-5683405 https://reactome.org/PathwayBrowser/#/R-HSA-5683405 PPP5C dephosphorylates TP53BP1 TAS Homo sapiens 43474 R-HSA-5683714 https://reactome.org/PathwayBrowser/#/R-HSA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body TAS Homo sapiens 43474 R-HSA-5683925 https://reactome.org/PathwayBrowser/#/R-HSA-5683925 ULK1 is dephosphorylated TAS Homo sapiens 43474 R-HSA-5683967 https://reactome.org/PathwayBrowser/#/R-HSA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX TAS Homo sapiens 43474 R-HSA-5686410 https://reactome.org/PathwayBrowser/#/R-HSA-5686410 BLM mediates dissolution of double Holliday junction TAS Homo sapiens 43474 R-HSA-5687585 https://reactome.org/PathwayBrowser/#/R-HSA-5687585 Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol TAS Homo sapiens 43474 R-HSA-5687758 https://reactome.org/PathwayBrowser/#/R-HSA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 TAS Homo sapiens 43474 R-HSA-5690996 https://reactome.org/PathwayBrowser/#/R-HSA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA TAS Homo sapiens 43474 R-HSA-5692462 https://reactome.org/PathwayBrowser/#/R-HSA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen TAS Homo sapiens 43474 R-HSA-5692480 https://reactome.org/PathwayBrowser/#/R-HSA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen TAS Homo sapiens 43474 R-HSA-5692754 https://reactome.org/PathwayBrowser/#/R-HSA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 TAS Homo sapiens 43474 R-HSA-5693153 https://reactome.org/PathwayBrowser/#/R-HSA-5693153 PPM1K dephosphorylates p-BCKDH TAS Homo sapiens 43474 R-HSA-5693589 https://reactome.org/PathwayBrowser/#/R-HSA-5693589 D-loop dissociation and strand annealing TAS Homo sapiens 43474 R-HSA-5694126 https://reactome.org/PathwayBrowser/#/R-HSA-5694126 NT5C3B hydrolyses 7MGP to 7MG TAS Homo sapiens 43474 R-HSA-5694421 https://reactome.org/PathwayBrowser/#/R-HSA-5694421 PP6 dephosphorylates SEC24 TAS Homo sapiens 43474 R-HSA-5694425 https://reactome.org/PathwayBrowser/#/R-HSA-5694425 NSF ATPase activity dissociates cis-SNARE TAS Homo sapiens 43474 R-HSA-5694527 https://reactome.org/PathwayBrowser/#/R-HSA-5694527 Loss of SAR1B GTPase TAS Homo sapiens 43474 R-HSA-5696408 https://reactome.org/PathwayBrowser/#/R-HSA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL TAS Homo sapiens 43474 R-HSA-5696415 https://reactome.org/PathwayBrowser/#/R-HSA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA TAS Homo sapiens 43474 R-HSA-5696839 https://reactome.org/PathwayBrowser/#/R-HSA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF TAS Homo sapiens 43474 R-HSA-6782131 https://reactome.org/PathwayBrowser/#/R-HSA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER TAS Homo sapiens 43474 R-HSA-6783483 https://reactome.org/PathwayBrowser/#/R-HSA-6783483 tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol TAS Homo sapiens 43474 R-HSA-6786245 https://reactome.org/PathwayBrowser/#/R-HSA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN TAS Homo sapiens 43474 R-HSA-6788295 https://reactome.org/PathwayBrowser/#/R-HSA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP TAS Homo sapiens 43474 R-HSA-6788912 https://reactome.org/PathwayBrowser/#/R-HSA-6788912 LHPP:Mg2+ dimer hydrolyses PPi TAS Homo sapiens 43474 R-HSA-6790987 https://reactome.org/PathwayBrowser/#/R-HSA-6790987 NAT10 acetylates cytidine-1337 and cytidine-1842 of 18S rRNA yielding 4-acetylcytidine-1377 and 4-acetylcytidine-1842 TAS Homo sapiens 43474 R-HSA-6792863 https://reactome.org/PathwayBrowser/#/R-HSA-6792863 PP2A-PP2R5C dephosphorylates MDM2 TAS Homo sapiens 43474 R-HSA-6797630 https://reactome.org/PathwayBrowser/#/R-HSA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA TAS Homo sapiens 43474 R-HSA-6801342 https://reactome.org/PathwayBrowser/#/R-HSA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG TAS Homo sapiens 43474 R-HSA-6801456 https://reactome.org/PathwayBrowser/#/R-HSA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF TAS Homo sapiens 43474 R-HSA-6803545 https://reactome.org/PathwayBrowser/#/R-HSA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen TAS Homo sapiens 43474 R-HSA-6806967 https://reactome.org/PathwayBrowser/#/R-HSA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH TAS Homo sapiens 43474 R-HSA-6807008 https://reactome.org/PathwayBrowser/#/R-HSA-6807008 PTPRJ dephosphorylates MET TAS Homo sapiens 43474 R-HSA-6807027 https://reactome.org/PathwayBrowser/#/R-HSA-6807027 PTPN1 and PTPN2 dephosphorylate MET TAS Homo sapiens 43474 R-HSA-6809015 https://reactome.org/PathwayBrowser/#/R-HSA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi TAS Homo sapiens 43474 R-HSA-6809320 https://reactome.org/PathwayBrowser/#/R-HSA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane TAS Homo sapiens 43474 R-HSA-6809325 https://reactome.org/PathwayBrowser/#/R-HSA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane TAS Homo sapiens 43474 R-HSA-6809561 https://reactome.org/PathwayBrowser/#/R-HSA-6809561 I(1,3)P2 is dephosphorylated into I1P by MTMR7 IEA Homo sapiens 43474 R-HSA-6809565 https://reactome.org/PathwayBrowser/#/R-HSA-6809565 I(1,3)P2 is dephosphorylated into I1P by MTMR7:MTMR9 IEA Homo sapiens 43474 R-HSA-6809720 https://reactome.org/PathwayBrowser/#/R-HSA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 TAS Homo sapiens 43474 R-HSA-6809777 https://reactome.org/PathwayBrowser/#/R-HSA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 TAS Homo sapiens 43474 R-HSA-6809778 https://reactome.org/PathwayBrowser/#/R-HSA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 TAS Homo sapiens 43474 R-HSA-6809944 https://reactome.org/PathwayBrowser/#/R-HSA-6809944 PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane IEA Homo sapiens 43474 R-HSA-6809975 https://reactome.org/PathwayBrowser/#/R-HSA-6809975 PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane IEA Homo sapiens 43474 R-HSA-6810410 https://reactome.org/PathwayBrowser/#/R-HSA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus TAS Homo sapiens 43474 R-HSA-6811422 https://reactome.org/PathwayBrowser/#/R-HSA-6811422 NSF ATPase activity dissociates cis-SNARE at the ER TAS Homo sapiens 43474 R-HSA-6811504 https://reactome.org/PathwayBrowser/#/R-HSA-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma TAS Homo sapiens 43474 R-HSA-6814120 https://reactome.org/PathwayBrowser/#/R-HSA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT TAS Homo sapiens 43474 R-HSA-6814554 https://reactome.org/PathwayBrowser/#/R-HSA-6814554 Dephosphorylation and dissociation of RNA polymerase II at 3' end of snRNA gene IEA Homo sapiens 43474 R-HSA-68954 https://reactome.org/PathwayBrowser/#/R-HSA-68954 Mcm2-7 is phosphorylated by DDK TAS Homo sapiens 43474 R-HSA-69199 https://reactome.org/PathwayBrowser/#/R-HSA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A TAS Homo sapiens 43474 R-HSA-70262 https://reactome.org/PathwayBrowser/#/R-HSA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate TAS Homo sapiens 43474 R-HSA-70449 https://reactome.org/PathwayBrowser/#/R-HSA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ TAS Homo sapiens 43474 R-HSA-70479 https://reactome.org/PathwayBrowser/#/R-HSA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P TAS Homo sapiens 43474 R-HSA-70482 https://reactome.org/PathwayBrowser/#/R-HSA-70482 GAPDH tetramers reduce 1,3BPG to GA3P TAS Homo sapiens 43474 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 43474 R-HSA-70555 https://reactome.org/PathwayBrowser/#/R-HSA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] TAS Homo sapiens 43474 R-HSA-70560 https://reactome.org/PathwayBrowser/#/R-HSA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate TAS Homo sapiens 43474 R-HSA-70606 https://reactome.org/PathwayBrowser/#/R-HSA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] TAS Homo sapiens 43474 R-HSA-70773 https://reactome.org/PathwayBrowser/#/R-HSA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] TAS Homo sapiens 43474 R-HSA-70997 https://reactome.org/PathwayBrowser/#/R-HSA-70997 SUCLG1/A2 cleaves succinyl-CoA TAS Homo sapiens 43474 R-HSA-71031 https://reactome.org/PathwayBrowser/#/R-HSA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate TAS Homo sapiens 43474 R-HSA-71287 https://reactome.org/PathwayBrowser/#/R-HSA-71287 phosphocreatine + H2O => creatinine + orthophosphate TAS Homo sapiens 43474 R-HSA-71515 https://reactome.org/PathwayBrowser/#/R-HSA-71515 glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] IEA Homo sapiens 43474 R-HSA-71590 https://reactome.org/PathwayBrowser/#/R-HSA-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] TAS Homo sapiens 43474 R-HSA-71732 https://reactome.org/PathwayBrowser/#/R-HSA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate TAS Homo sapiens 43474 R-HSA-71775 https://reactome.org/PathwayBrowser/#/R-HSA-71775 SUCLG1/G2 cleaves succinyl-CoA TAS Homo sapiens 43474 R-HSA-71825 https://reactome.org/PathwayBrowser/#/R-HSA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) TAS Homo sapiens 43474 R-HSA-72619 https://reactome.org/PathwayBrowser/#/R-HSA-72619 eIF2:GTP is hydrolyzed, eIFs are released TAS Homo sapiens 43474 R-HSA-72621 https://reactome.org/PathwayBrowser/#/R-HSA-72621 Ribosomal scanning TAS Homo sapiens 43474 R-HSA-72647 https://reactome.org/PathwayBrowser/#/R-HSA-72647 Cap-bound mRNA is activated by helicases TAS Homo sapiens 43474 R-HSA-72671 https://reactome.org/PathwayBrowser/#/R-HSA-72671 eIF5B:GTP is hydrolyzed and released TAS Homo sapiens 43474 R-HSA-73573 https://reactome.org/PathwayBrowser/#/R-HSA-73573 CAD hexamer transforms CAP to N-carb-L-Asp TAS Homo sapiens 43474 R-HSA-73577 https://reactome.org/PathwayBrowser/#/R-HSA-73577 CAD hexamer transforms L-Gln to CAP TAS Homo sapiens 43474 R-HSA-73647 https://reactome.org/PathwayBrowser/#/R-HSA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] TAS Homo sapiens 43474 R-HSA-73805 https://reactome.org/PathwayBrowser/#/R-HSA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi TAS Homo sapiens 43474 R-HSA-73810 https://reactome.org/PathwayBrowser/#/R-HSA-73810 FGAM + ATP => AIR + ADP + Pi TAS Homo sapiens 43474 R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 43474 R-HSA-73814 https://reactome.org/PathwayBrowser/#/R-HSA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi TAS Homo sapiens 43474 R-HSA-74242 https://reactome.org/PathwayBrowser/#/R-HSA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 43474 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 43474 R-HSA-74249 https://reactome.org/PathwayBrowser/#/R-HSA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 43474 R-HSA-74372 https://reactome.org/PathwayBrowser/#/R-HSA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] TAS Homo sapiens 43474 R-HSA-74376 https://reactome.org/PathwayBrowser/#/R-HSA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) TAS Homo sapiens 43474 R-HSA-74733 https://reactome.org/PathwayBrowser/#/R-HSA-74733 Insulin receptor de-phosphorylation TAS Homo sapiens 43474 R-HSA-74747 https://reactome.org/PathwayBrowser/#/R-HSA-74747 Dephosphorylation of p-Y-IRS1,p-Y-IRS2 TAS Homo sapiens 43474 R-HSA-74748 https://reactome.org/PathwayBrowser/#/R-HSA-74748 De-phosphorylation of p-Y427-SHC1 TAS Homo sapiens 43474 R-HSA-74948 https://reactome.org/PathwayBrowser/#/R-HSA-74948 PP2A dephosphorylates p-RHO to RHO TAS Homo sapiens 43474 R-HSA-75848 https://reactome.org/PathwayBrowser/#/R-HSA-75848 ACLY tetramer transforms CIT to Ac-CoA TAS Homo sapiens 43474 R-HSA-75851 https://reactome.org/PathwayBrowser/#/R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 43474 R-HSA-75899 https://reactome.org/PathwayBrowser/#/R-HSA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate TAS Homo sapiens 43474 R-HSA-75949 https://reactome.org/PathwayBrowser/#/R-HSA-75949 RNA Polymerase II Promoter Opening: First Transition TAS Homo sapiens 43474 R-HSA-77078 https://reactome.org/PathwayBrowser/#/R-HSA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme TAS Homo sapiens 43474 R-HSA-877308 https://reactome.org/PathwayBrowser/#/R-HSA-877308 Dephosphorylation of JAKs by PTPs IEA Homo sapiens 43474 R-HSA-8848053 https://reactome.org/PathwayBrowser/#/R-HSA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol TAS Homo sapiens 43474 R-HSA-8849082 https://reactome.org/PathwayBrowser/#/R-HSA-8849082 ARHGAP35 stimulates RHOA GTPase activity TAS Homo sapiens 43474 R-HSA-8849435 https://reactome.org/PathwayBrowser/#/R-HSA-8849435 PTPN1 dephosphorylates PTK6 TAS Homo sapiens 43474 R-HSA-8849969 https://reactome.org/PathwayBrowser/#/R-HSA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane TAS Homo sapiens 43474 R-HSA-8850846 https://reactome.org/PathwayBrowser/#/R-HSA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates TAS Homo sapiens 43474 R-HSA-8850854 https://reactome.org/PathwayBrowser/#/R-HSA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates TAS Homo sapiens 43474 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 43474 R-HSA-8851110 https://reactome.org/PathwayBrowser/#/R-HSA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates TAS Homo sapiens 43474 R-HSA-8851129 https://reactome.org/PathwayBrowser/#/R-HSA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates TAS Homo sapiens 43474 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 43474 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 43474 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 43474 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 43474 R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 43474 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 43474 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 43474 R-HSA-8852200 https://reactome.org/PathwayBrowser/#/R-HSA-8852200 Inactivation of LCK by PTPN22 TAS Homo sapiens 43474 R-HSA-8854173 https://reactome.org/PathwayBrowser/#/R-HSA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 TAS Homo sapiens 43474 R-HSA-8854255 https://reactome.org/PathwayBrowser/#/R-HSA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 43474 R-HSA-8854329 https://reactome.org/PathwayBrowser/#/R-HSA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 43474 R-HSA-8854604 https://reactome.org/PathwayBrowser/#/R-HSA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A TAS Homo sapiens 43474 R-HSA-8854612 https://reactome.org/PathwayBrowser/#/R-HSA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B TAS Homo sapiens 43474 R-HSA-8855381 https://reactome.org/PathwayBrowser/#/R-HSA-8855381 PTPN22 dephosphorylates ZAP70 TAS Homo sapiens 43474 R-HSA-8863804 https://reactome.org/PathwayBrowser/#/R-HSA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 TAS Homo sapiens 43474 R-HSA-8864029 https://reactome.org/PathwayBrowser/#/R-HSA-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) TAS Homo sapiens 43474 R-HSA-8864036 https://reactome.org/PathwayBrowser/#/R-HSA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 TAS Homo sapiens 43474 R-HSA-8864125 https://reactome.org/PathwayBrowser/#/R-HSA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 TAS Homo sapiens 43474 R-HSA-8865774 https://reactome.org/PathwayBrowser/#/R-HSA-8865774 TTLLs polyglutamylate tubulin TAS Homo sapiens 43474 R-HSA-8866542 https://reactome.org/PathwayBrowser/#/R-HSA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol TAS Homo sapiens 43474 R-HSA-8866854 https://reactome.org/PathwayBrowser/#/R-HSA-8866854 VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol TAS Homo sapiens 43474 R-HSA-8867047 https://reactome.org/PathwayBrowser/#/R-HSA-8867047 PTPN3 dephosphorylates EPS15 TAS Homo sapiens 43474 R-HSA-8867370 https://reactome.org/PathwayBrowser/#/R-HSA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin TAS Homo sapiens 43474 R-HSA-8867658 https://reactome.org/PathwayBrowser/#/R-HSA-8867658 PTPN3 dephosphorylates MAPK12 TAS Homo sapiens 43474 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 43474 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 43474 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 43474 R-HSA-8876889 https://reactome.org/PathwayBrowser/#/R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 43474 R-HSA-8878654 https://reactome.org/PathwayBrowser/#/R-HSA-8878654 ACP6 hydrolyses MYS-LPA TAS Homo sapiens 43474 R-HSA-8878787 https://reactome.org/PathwayBrowser/#/R-HSA-8878787 ALPI dimer hydrolyses phosphate monoesters TAS Homo sapiens 43474 R-HSA-8937767 https://reactome.org/PathwayBrowser/#/R-HSA-8937767 PTPN11 dephosphorylates RUNX1 TAS Homo sapiens 43474 R-HSA-8939203 https://reactome.org/PathwayBrowser/#/R-HSA-8939203 HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex TAS Homo sapiens 43474 R-HSA-8940070 https://reactome.org/PathwayBrowser/#/R-HSA-8940070 NT5E:Zn2+ hydrolyses NAD+ TAS Homo sapiens 43474 R-HSA-8940074 https://reactome.org/PathwayBrowser/#/R-HSA-8940074 NT5E:Zn2+ hydrolyses NMN TAS Homo sapiens 43474 R-HSA-8951498 https://reactome.org/PathwayBrowser/#/R-HSA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex TAS Homo sapiens 43474 R-HSA-8952137 https://reactome.org/PathwayBrowser/#/R-HSA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate TAS Homo sapiens 43474 R-HSA-8953499 https://reactome.org/PathwayBrowser/#/R-HSA-8953499 IMPAD1 hydrolyses PAP to AMP TAS Homo sapiens 43474 R-HSA-8955706 https://reactome.org/PathwayBrowser/#/R-HSA-8955706 TTL ligates L-Tyr to the carboxy terminus of detyr-alpha tubulin:beta tubulin IEA Homo sapiens 43474 R-HSA-8955794 https://reactome.org/PathwayBrowser/#/R-HSA-8955794 PGP:Mg2+ dimer hydrolyses 3PG to glycerol IEA Homo sapiens 43474 R-HSA-8955869 https://reactome.org/PathwayBrowser/#/R-HSA-8955869 Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin IEA Homo sapiens 43474 R-HSA-8959510 https://reactome.org/PathwayBrowser/#/R-HSA-8959510 SEPHS2 phosphorylates H2Se to form SELP TAS Homo sapiens 43474 R-HSA-8981637 https://reactome.org/PathwayBrowser/#/R-HSA-8981637 RHOA GAPs stimulate RHOA GTPase activity TAS Homo sapiens 43474 R-HSA-8982020 https://reactome.org/PathwayBrowser/#/R-HSA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated TAS Homo sapiens 43474 R-HSA-8982021 https://reactome.org/PathwayBrowser/#/R-HSA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated TAS Homo sapiens 43474 R-HSA-8982025 https://reactome.org/PathwayBrowser/#/R-HSA-8982025 G alpha (q) in G (q):RGS complex is inactivated TAS Homo sapiens 43474 R-HSA-8985594 https://reactome.org/PathwayBrowser/#/R-HSA-8985594 MYO9B inactivates RHOA TAS Homo sapiens 43474 R-HSA-9013022 https://reactome.org/PathwayBrowser/#/R-HSA-9013022 RHOB GAPs stimulate RHOB GTPase activity TAS Homo sapiens 43474 R-HSA-9013111 https://reactome.org/PathwayBrowser/#/R-HSA-9013111 RHOC GAPs stimulate RHOC GTPase activity TAS Homo sapiens 43474 R-HSA-9013144 https://reactome.org/PathwayBrowser/#/R-HSA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity TAS Homo sapiens 43474 R-HSA-9013161 https://reactome.org/PathwayBrowser/#/R-HSA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity TAS Homo sapiens 43474 R-HSA-9013437 https://reactome.org/PathwayBrowser/#/R-HSA-9013437 RHOD GAPs stimulate RHOD GTPase activity TAS Homo sapiens 43474 R-HSA-9014295 https://reactome.org/PathwayBrowser/#/R-HSA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity TAS Homo sapiens 43474 R-HSA-9014434 https://reactome.org/PathwayBrowser/#/R-HSA-9014434 RHOG GAPs stimulate RHOG GTPase activity TAS Homo sapiens 43474 R-HSA-9017488 https://reactome.org/PathwayBrowser/#/R-HSA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity TAS Homo sapiens 43474 R-HSA-9018745 https://reactome.org/PathwayBrowser/#/R-HSA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity TAS Homo sapiens 43474 R-HSA-9018806 https://reactome.org/PathwayBrowser/#/R-HSA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity TAS Homo sapiens 43474 R-HSA-9018814 https://reactome.org/PathwayBrowser/#/R-HSA-9018814 RHOT1 hydrolyzes GTP TAS Homo sapiens 43474 R-HSA-9018826 https://reactome.org/PathwayBrowser/#/R-HSA-9018826 RHOT2 hydrolyzes GTP TAS Homo sapiens 43474 R-HSA-9032751 https://reactome.org/PathwayBrowser/#/R-HSA-9032751 Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3 TAS Homo sapiens 43474 R-HSA-9038161 https://reactome.org/PathwayBrowser/#/R-HSA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG TAS Homo sapiens 43474 R-HSA-917693 https://reactome.org/PathwayBrowser/#/R-HSA-917693 ESCRT Disassembly TAS Homo sapiens 43474 R-HSA-917841 https://reactome.org/PathwayBrowser/#/R-HSA-917841 Acidification of Tf:TfR1 containing endosome TAS Homo sapiens 43474 R-HSA-917979 https://reactome.org/PathwayBrowser/#/R-HSA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-936802 https://reactome.org/PathwayBrowser/#/R-HSA-936802 ATP7A transports cytosolic Cu2+ to extracellular region TAS Homo sapiens 43474 R-HSA-936883 https://reactome.org/PathwayBrowser/#/R-HSA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen TAS Homo sapiens 43474 R-HSA-936895 https://reactome.org/PathwayBrowser/#/R-HSA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen TAS Homo sapiens 43474 R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 43474 R-HSA-937311 https://reactome.org/PathwayBrowser/#/R-HSA-937311 ATP12A:ATP4B exchanges K+ for H+ TAS Homo sapiens 43474 R-HSA-939763 https://reactome.org/PathwayBrowser/#/R-HSA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane TAS Homo sapiens 43474 R-HSA-947591 https://reactome.org/PathwayBrowser/#/R-HSA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane TAS Homo sapiens 43474 R-HSA-9603719 https://reactome.org/PathwayBrowser/#/R-HSA-9603719 Protein tyrosine phosphatases dephosphorylate NTRK3 IEA Homo sapiens 43474 R-HSA-9609860 https://reactome.org/PathwayBrowser/#/R-HSA-9609860 Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP IEA Homo sapiens 43474 R-HSA-9610627 https://reactome.org/PathwayBrowser/#/R-HSA-9610627 KIF17 transports GluN1:GluN2B (GRIN1:GRIN2B) NMDA receptors to the plasma membrane IEA Homo sapiens 43474 R-HSA-9619430 https://reactome.org/PathwayBrowser/#/R-HSA-9619430 PPM1E dephosphorylates CAMK4 IEA Homo sapiens 43474 R-HSA-9619449 https://reactome.org/PathwayBrowser/#/R-HSA-9619449 PPM1F dephosphorylates p-T286-CaMKII IEA Homo sapiens 43474 R-HSA-9619467 https://reactome.org/PathwayBrowser/#/R-HSA-9619467 PPM1F dephosphorylates CAMK1 IEA Homo sapiens 43474 R-HSA-9624893 https://reactome.org/PathwayBrowser/#/R-HSA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes TAS Homo sapiens 43474 R-HSA-9635461 https://reactome.org/PathwayBrowser/#/R-HSA-9635461 PtpA dephosphorylates GSK3A TAS Homo sapiens 43474 R-HSA-9635739 https://reactome.org/PathwayBrowser/#/R-HSA-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs TAS Homo sapiens 43474 R-HSA-9636439 https://reactome.org/PathwayBrowser/#/R-HSA-9636439 PtpA:Ub dephosphorylates p-Y133-VPS33B TAS Homo sapiens 43474 R-HSA-9636457 https://reactome.org/PathwayBrowser/#/R-HSA-9636457 SapM dephosphorylates PI3P TAS Homo sapiens 43474 R-HSA-9636684 https://reactome.org/PathwayBrowser/#/R-HSA-9636684 ndkA dephosphorylates RAB5A:GTP,RAB7A:GTP TAS Homo sapiens 43474 R-HSA-9640195 https://reactome.org/PathwayBrowser/#/R-HSA-9640195 RRAGA,B hydrolyzes GTP TAS Homo sapiens 43474 R-HSA-9645598 https://reactome.org/PathwayBrowser/#/R-HSA-9645598 RRAGC,D hydrolyzes GTP TAS Homo sapiens 43474 R-HSA-965067 https://reactome.org/PathwayBrowser/#/R-HSA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP TAS Homo sapiens 43474 R-HSA-9658445 https://reactome.org/PathwayBrowser/#/R-HSA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs TAS Homo sapiens 43474 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 43474 R-HSA-9660538 https://reactome.org/PathwayBrowser/#/R-HSA-9660538 Mutant MRAS:SHOC2:PPP1CC complexes dephosphorylate inactive RAFs TAS Homo sapiens 43474 R-HSA-9661417 https://reactome.org/PathwayBrowser/#/R-HSA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-9662114 https://reactome.org/PathwayBrowser/#/R-HSA-9662114 ATP2B2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region IEA Homo sapiens 43474 R-HSA-9664214 https://reactome.org/PathwayBrowser/#/R-HSA-9664214 ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region IEA Homo sapiens 43474 R-HSA-9666458 https://reactome.org/PathwayBrowser/#/R-HSA-9666458 IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole TAS Homo sapiens 43474 R-HSA-9668415 https://reactome.org/PathwayBrowser/#/R-HSA-9668415 VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope TAS Homo sapiens 43474 R-HSA-9668419 https://reactome.org/PathwayBrowser/#/R-HSA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites TAS Homo sapiens 43474 R-HSA-9674816 https://reactome.org/PathwayBrowser/#/R-HSA-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS TAS Homo sapiens 43474 R-HSA-9682695 https://reactome.org/PathwayBrowser/#/R-HSA-9682695 nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template TAS Homo sapiens 43474 R-HSA-9684016 https://reactome.org/PathwayBrowser/#/R-HSA-9684016 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 43474 R-HSA-9684017 https://reactome.org/PathwayBrowser/#/R-HSA-9684017 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 43474 R-HSA-9684018 https://reactome.org/PathwayBrowser/#/R-HSA-9684018 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 43474 R-HSA-9684118 https://reactome.org/PathwayBrowser/#/R-HSA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER TAS Homo sapiens 43474 R-HSA-9686524 https://reactome.org/PathwayBrowser/#/R-HSA-9686524 PP6-PPP6R3 dephosphorylates TERF2 TAS Homo sapiens 43474 R-HSA-9693282 https://reactome.org/PathwayBrowser/#/R-HSA-9693282 RHOF GAPs stimulate RHOF GTPase activity TAS Homo sapiens 43474 R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 43474 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 43474 R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 43474 R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 43474 R-HSA-9698408 https://reactome.org/PathwayBrowser/#/R-HSA-9698408 PTPRJ dephosphorylates active FLT3 TAS Homo sapiens 43474 R-HSA-9700200 https://reactome.org/PathwayBrowser/#/R-HSA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers TAS Homo sapiens 43474 R-HSA-9701507 https://reactome.org/PathwayBrowser/#/R-HSA-9701507 PTPN6 dephosphorylates JAK3 TAS Homo sapiens 43474 R-HSA-9706399 https://reactome.org/PathwayBrowser/#/R-HSA-9706399 RHOBTB3 hydrolyzes ATP TAS Homo sapiens 43474 R-HSA-9727198 https://reactome.org/PathwayBrowser/#/R-HSA-9727198 ATP4A:ATP4B exchanges K+ for H+ TAS Homo sapiens 43474 R-HSA-9735775 https://reactome.org/PathwayBrowser/#/R-HSA-9735775 Defective PNP does not convert (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 43474 R-HSA-9735789 https://reactome.org/PathwayBrowser/#/R-HSA-9735789 Defective PNP does not convert (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 43474 R-HSA-9750546 https://reactome.org/PathwayBrowser/#/R-HSA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-9750617 https://reactome.org/PathwayBrowser/#/R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-9750656 https://reactome.org/PathwayBrowser/#/R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells TAS Homo sapiens 43474 R-HSA-9753278 https://reactome.org/PathwayBrowser/#/R-HSA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 43474 R-HSA-9753283 https://reactome.org/PathwayBrowser/#/R-HSA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 43474 R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 43474 R-HSA-9759206 https://reactome.org/PathwayBrowser/#/R-HSA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol TAS Homo sapiens 43474 R-HSA-9759454 https://reactome.org/PathwayBrowser/#/R-HSA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells TAS Homo sapiens 43474 R-HSA-9759461 https://reactome.org/PathwayBrowser/#/R-HSA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells TAS Homo sapiens 43474 R-HSA-9770129 https://reactome.org/PathwayBrowser/#/R-HSA-9770129 Formation of the Spliceosomal A complex TAS Homo sapiens 43474 R-HSA-9770131 https://reactome.org/PathwayBrowser/#/R-HSA-9770131 Formation of the Spliceosomal B* complex TAS Homo sapiens 43474 R-HSA-9770141 https://reactome.org/PathwayBrowser/#/R-HSA-9770141 Formation of the Spliceosomal C* complex TAS Homo sapiens 43474 R-HSA-9770142 https://reactome.org/PathwayBrowser/#/R-HSA-9770142 Formation of the Spliceosomal B complex TAS Homo sapiens 43474 R-HSA-9770145 https://reactome.org/PathwayBrowser/#/R-HSA-9770145 Formation of the Spliceosomal Bact complex TAS Homo sapiens 43474 R-HSA-9770847 https://reactome.org/PathwayBrowser/#/R-HSA-9770847 Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) TAS Homo sapiens 43474 R-HSA-9772351 https://reactome.org/PathwayBrowser/#/R-HSA-9772351 Disassembly of the Intron Lariat Spliceosome (new) TAS Homo sapiens 43474 R-HSA-977324 https://reactome.org/PathwayBrowser/#/R-HSA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser TAS Homo sapiens 43474 R-HSA-9830848 https://reactome.org/PathwayBrowser/#/R-HSA-9830848 L protein acts as a cap N7 methyltransferase to modify RSV mRNAs TAS Homo sapiens 43474 R-HSA-983144 https://reactome.org/PathwayBrowser/#/R-HSA-983144 Transport of Antigen peptide in to ER TAS Homo sapiens 43474 R-HSA-9831948 https://reactome.org/PathwayBrowser/#/R-HSA-9831948 P:PP1 dephosphorylates M2-1 TAS Homo sapiens 43474 R-HSA-9836927 https://reactome.org/PathwayBrowser/#/R-HSA-9836927 SUPV3L1 unwinds double-stranded mitochondiral RNA TAS Homo sapiens 43474 R-HSA-9837419 https://reactome.org/PathwayBrowser/#/R-HSA-9837419 PANK4 hydrolyzes PPANT to pantetheine TAS Homo sapiens 43474 R-HSA-9838004 https://reactome.org/PathwayBrowser/#/R-HSA-9838004 LONP1 degrades mitochondrial inner membrane proteins TAS Homo sapiens 43474 R-HSA-9838081 https://reactome.org/PathwayBrowser/#/R-HSA-9838081 LONP1 degrades mitochondrial matrix proteins TAS Homo sapiens 43474 R-HSA-9838289 https://reactome.org/PathwayBrowser/#/R-HSA-9838289 CLPXP degrades mitochondrial matrix proteins TAS Homo sapiens 43474 R-HSA-9839059 https://reactome.org/PathwayBrowser/#/R-HSA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) TAS Homo sapiens 43474 R-HSA-9839105 https://reactome.org/PathwayBrowser/#/R-HSA-9839105 AFG3L2 degrades mitochondrial matrix proteins TAS Homo sapiens 43474 R-HSA-9839113 https://reactome.org/PathwayBrowser/#/R-HSA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins TAS Homo sapiens 43474 R-HSA-9839146 https://reactome.org/PathwayBrowser/#/R-HSA-9839146 YME1L1 degrades mitochondrial inner membrane proteins IEA Homo sapiens 43474 R-HSA-9839751 https://reactome.org/PathwayBrowser/#/R-HSA-9839751 YME1L1 degrades mitochondrial intermembrane space proteins IEA Homo sapiens 43474 R-HSA-9843721 https://reactome.org/PathwayBrowser/#/R-HSA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region TAS Homo sapiens 43474 R-HSA-9853385 https://reactome.org/PathwayBrowser/#/R-HSA-9853385 PPP1CC dephosphorylates PLK1 TAS Homo sapiens 43474 R-HSA-9861725 https://reactome.org/PathwayBrowser/#/R-HSA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 TAS Homo sapiens 43474 R-HSA-997309 https://reactome.org/PathwayBrowser/#/R-HSA-997309 Dephosphorylation of STAT1 by SHP2 TAS Homo sapiens 43474 R-HSA-997311 https://reactome.org/PathwayBrowser/#/R-HSA-997311 Dephosphorylation of TYK2 by PTP1B TAS Homo sapiens 43474 R-HSA-997314 https://reactome.org/PathwayBrowser/#/R-HSA-997314 Dephosphorylation of JAK1 by SHP1 TAS Homo sapiens 43474 R-HSA-997326 https://reactome.org/PathwayBrowser/#/R-HSA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP TAS Homo sapiens 43474 R-MGA-421635 https://reactome.org/PathwayBrowser/#/R-MGA-421635 Myosin phosphatase dephosphorylates myosin regulatory light chain TAS Meleagris gallopavo 43474 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 43474 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 43474 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 43474 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 43474 R-MMU-109415 https://reactome.org/PathwayBrowser/#/R-MMU-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Mus musculus 43474 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 43474 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 43474 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 43474 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 43474 R-MMU-111215 https://reactome.org/PathwayBrowser/#/R-MMU-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Mus musculus 43474 R-MMU-111519 https://reactome.org/PathwayBrowser/#/R-MMU-111519 inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate TAS Mus musculus 43474 R-MMU-111524 https://reactome.org/PathwayBrowser/#/R-MMU-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Mus musculus 43474 R-MMU-112033 https://reactome.org/PathwayBrowser/#/R-MMU-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Mus musculus 43474 R-MMU-112034 https://reactome.org/PathwayBrowser/#/R-MMU-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Mus musculus 43474 R-MMU-112037 https://reactome.org/PathwayBrowser/#/R-MMU-112037 Inactivation of PLC beta IEA Mus musculus 43474 R-MMU-112265 https://reactome.org/PathwayBrowser/#/R-MMU-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Mus musculus 43474 R-MMU-112266 https://reactome.org/PathwayBrowser/#/R-MMU-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Mus musculus 43474 R-MMU-113503 https://reactome.org/PathwayBrowser/#/R-MMU-113503 PP2A mediated localization of RB1 protein in chromatin IEA Mus musculus 43474 R-MMU-1169192 https://reactome.org/PathwayBrowser/#/R-MMU-1169192 PTP1B dephosphorylates GHR IEA Mus musculus 43474 R-MMU-1169229 https://reactome.org/PathwayBrowser/#/R-MMU-1169229 Ptp1b dephosphorylates Jak2 TAS Mus musculus 43474 R-MMU-1169240 https://reactome.org/PathwayBrowser/#/R-MMU-1169240 Shp1 (Ptpn6) dephosphorylates Jak2 TAS Mus musculus 43474 R-MMU-1237129 https://reactome.org/PathwayBrowser/#/R-MMU-1237129 Acireductone is created IEA Mus musculus 43474 R-MMU-1237160 https://reactome.org/PathwayBrowser/#/R-MMU-1237160 MTA is cleaved and phosphorylated IEA Mus musculus 43474 R-MMU-1247935 https://reactome.org/PathwayBrowser/#/R-MMU-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Mus musculus 43474 R-MMU-1295632 https://reactome.org/PathwayBrowser/#/R-MMU-1295632 PPA2A dephosphorylates SPRY2 IEA Mus musculus 43474 R-MMU-1363274 https://reactome.org/PathwayBrowser/#/R-MMU-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Mus musculus 43474 R-MMU-1363276 https://reactome.org/PathwayBrowser/#/R-MMU-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Mus musculus 43474 R-MMU-1369028 https://reactome.org/PathwayBrowser/#/R-MMU-1369028 ABCAs mediate lipid efflux IEA Mus musculus 43474 R-MMU-1369052 https://reactome.org/PathwayBrowser/#/R-MMU-1369052 ABCAs mediate lipid influx IEA Mus musculus 43474 R-MMU-1369065 https://reactome.org/PathwayBrowser/#/R-MMU-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Mus musculus 43474 R-MMU-139906 https://reactome.org/PathwayBrowser/#/R-MMU-139906 Activation of BAD by calcineurin IEA Mus musculus 43474 R-MMU-1454916 https://reactome.org/PathwayBrowser/#/R-MMU-1454916 The ABCC family mediates organic anion transport IEA Mus musculus 43474 R-MMU-1454928 https://reactome.org/PathwayBrowser/#/R-MMU-1454928 ABCG4 may mediate cholesterol efflux IEA Mus musculus 43474 R-MMU-1458501 https://reactome.org/PathwayBrowser/#/R-MMU-1458501 RalA Hydrolyzes GTP TAS Mus musculus 43474 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-1467466 https://reactome.org/PathwayBrowser/#/R-MMU-1467466 ABCA4 mediates atRAL transport IEA Mus musculus 43474 R-MMU-1483096 https://reactome.org/PathwayBrowser/#/R-MMU-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Mus musculus 43474 R-MMU-1483159 https://reactome.org/PathwayBrowser/#/R-MMU-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Mus musculus 43474 R-MMU-1483203 https://reactome.org/PathwayBrowser/#/R-MMU-1483203 PA is dephosphorylated to DAG by LPIN IEA Mus musculus 43474 R-MMU-159101 https://reactome.org/PathwayBrowser/#/R-MMU-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Mus musculus 43474 R-MMU-163120 https://reactome.org/PathwayBrowser/#/R-MMU-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Mus musculus 43474 R-MMU-1638821 https://reactome.org/PathwayBrowser/#/R-MMU-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Mus musculus 43474 R-MMU-164832 https://reactome.org/PathwayBrowser/#/R-MMU-164832 ATPase synthesizes ATP IEA Mus musculus 43474 R-MMU-164840 https://reactome.org/PathwayBrowser/#/R-MMU-164840 ADP and Pi bind to ATPase IEA Mus musculus 43474 R-MMU-1675795 https://reactome.org/PathwayBrowser/#/R-MMU-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Mus musculus 43474 R-MMU-1675824 https://reactome.org/PathwayBrowser/#/R-MMU-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Mus musculus 43474 R-MMU-1675836 https://reactome.org/PathwayBrowser/#/R-MMU-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Mus musculus 43474 R-MMU-1675949 https://reactome.org/PathwayBrowser/#/R-MMU-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Mus musculus 43474 R-MMU-1675988 https://reactome.org/PathwayBrowser/#/R-MMU-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Mus musculus 43474 R-MMU-1675994 https://reactome.org/PathwayBrowser/#/R-MMU-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Mus musculus 43474 R-MMU-1676005 https://reactome.org/PathwayBrowser/#/R-MMU-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Mus musculus 43474 R-MMU-1676020 https://reactome.org/PathwayBrowser/#/R-MMU-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Mus musculus 43474 R-MMU-1676065 https://reactome.org/PathwayBrowser/#/R-MMU-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Mus musculus 43474 R-MMU-1676105 https://reactome.org/PathwayBrowser/#/R-MMU-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Mus musculus 43474 R-MMU-1676114 https://reactome.org/PathwayBrowser/#/R-MMU-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Mus musculus 43474 R-MMU-1676124 https://reactome.org/PathwayBrowser/#/R-MMU-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Mus musculus 43474 R-MMU-1676133 https://reactome.org/PathwayBrowser/#/R-MMU-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Mus musculus 43474 R-MMU-1676141 https://reactome.org/PathwayBrowser/#/R-MMU-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Mus musculus 43474 R-MMU-1676149 https://reactome.org/PathwayBrowser/#/R-MMU-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Mus musculus 43474 R-MMU-1676162 https://reactome.org/PathwayBrowser/#/R-MMU-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Mus musculus 43474 R-MMU-1676164 https://reactome.org/PathwayBrowser/#/R-MMU-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Mus musculus 43474 R-MMU-1676174 https://reactome.org/PathwayBrowser/#/R-MMU-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Mus musculus 43474 R-MMU-1676177 https://reactome.org/PathwayBrowser/#/R-MMU-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Mus musculus 43474 R-MMU-1676203 https://reactome.org/PathwayBrowser/#/R-MMU-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Mus musculus 43474 R-MMU-1676204 https://reactome.org/PathwayBrowser/#/R-MMU-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Mus musculus 43474 R-MMU-170153 https://reactome.org/PathwayBrowser/#/R-MMU-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Mus musculus 43474 R-MMU-170158 https://reactome.org/PathwayBrowser/#/R-MMU-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Mus musculus 43474 R-MMU-170161 https://reactome.org/PathwayBrowser/#/R-MMU-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Mus musculus 43474 R-MMU-170666 https://reactome.org/PathwayBrowser/#/R-MMU-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Mus musculus 43474 R-MMU-170685 https://reactome.org/PathwayBrowser/#/R-MMU-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Mus musculus 43474 R-MMU-170686 https://reactome.org/PathwayBrowser/#/R-MMU-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Mus musculus 43474 R-MMU-174110 https://reactome.org/PathwayBrowser/#/R-MMU-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Mus musculus 43474 R-MMU-174367 https://reactome.org/PathwayBrowser/#/R-MMU-174367 GCL ligates L-Glu to L-Cys IEA Mus musculus 43474 R-MMU-174391 https://reactome.org/PathwayBrowser/#/R-MMU-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Mus musculus 43474 R-MMU-174394 https://reactome.org/PathwayBrowser/#/R-MMU-174394 GSS:Mg2+ dimer synthesizes GSH IEA Mus musculus 43474 R-MMU-174438 https://reactome.org/PathwayBrowser/#/R-MMU-174438 Formation of the Flap Intermediate on the C-strand IEA Mus musculus 43474 R-MMU-174439 https://reactome.org/PathwayBrowser/#/R-MMU-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Mus musculus 43474 R-MMU-176606 https://reactome.org/PathwayBrowser/#/R-MMU-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Mus musculus 43474 R-MMU-177923 https://reactome.org/PathwayBrowser/#/R-MMU-177923 Sustained activation of SRC kinase by SHP2 IEA Mus musculus 43474 R-MMU-177924 https://reactome.org/PathwayBrowser/#/R-MMU-177924 Dephosphorylation of Gab1 by SHP2 IEA Mus musculus 43474 R-MMU-177926 https://reactome.org/PathwayBrowser/#/R-MMU-177926 Dephosphorylation of PAG by SHP2 IEA Mus musculus 43474 R-MMU-177935 https://reactome.org/PathwayBrowser/#/R-MMU-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Mus musculus 43474 R-MMU-1855154 https://reactome.org/PathwayBrowser/#/R-MMU-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 43474 R-MMU-1855159 https://reactome.org/PathwayBrowser/#/R-MMU-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Mus musculus 43474 R-MMU-1855163 https://reactome.org/PathwayBrowser/#/R-MMU-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Mus musculus 43474 R-MMU-1855165 https://reactome.org/PathwayBrowser/#/R-MMU-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 43474 R-MMU-1855166 https://reactome.org/PathwayBrowser/#/R-MMU-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Mus musculus 43474 R-MMU-1855171 https://reactome.org/PathwayBrowser/#/R-MMU-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Mus musculus 43474 R-MMU-1855174 https://reactome.org/PathwayBrowser/#/R-MMU-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Mus musculus 43474 R-MMU-1855180 https://reactome.org/PathwayBrowser/#/R-MMU-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Mus musculus 43474 R-MMU-1855198 https://reactome.org/PathwayBrowser/#/R-MMU-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 43474 R-MMU-1855200 https://reactome.org/PathwayBrowser/#/R-MMU-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Mus musculus 43474 R-MMU-1855202 https://reactome.org/PathwayBrowser/#/R-MMU-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Mus musculus 43474 R-MMU-1855205 https://reactome.org/PathwayBrowser/#/R-MMU-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Mus musculus 43474 R-MMU-1855208 https://reactome.org/PathwayBrowser/#/R-MMU-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Mus musculus 43474 R-MMU-1855210 https://reactome.org/PathwayBrowser/#/R-MMU-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 43474 R-MMU-1855211 https://reactome.org/PathwayBrowser/#/R-MMU-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 43474 R-MMU-1855213 https://reactome.org/PathwayBrowser/#/R-MMU-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Mus musculus 43474 R-MMU-1855218 https://reactome.org/PathwayBrowser/#/R-MMU-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Mus musculus 43474 R-MMU-1855219 https://reactome.org/PathwayBrowser/#/R-MMU-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Mus musculus 43474 R-MMU-1855222 https://reactome.org/PathwayBrowser/#/R-MMU-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Mus musculus 43474 R-MMU-1855225 https://reactome.org/PathwayBrowser/#/R-MMU-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Mus musculus 43474 R-MMU-1855232 https://reactome.org/PathwayBrowser/#/R-MMU-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Mus musculus 43474 R-MMU-1861595 https://reactome.org/PathwayBrowser/#/R-MMU-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Mus musculus 43474 R-MMU-191414 https://reactome.org/PathwayBrowser/#/R-MMU-191414 MVD decarboxylates MVA5PP to IPPP IEA Mus musculus 43474 R-MMU-193362 https://reactome.org/PathwayBrowser/#/R-MMU-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-194153 https://reactome.org/PathwayBrowser/#/R-MMU-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-196950 https://reactome.org/PathwayBrowser/#/R-MMU-196950 2xTRAP hydrolyzes FMN to RIB IEA Mus musculus 43474 R-MMU-197958 https://reactome.org/PathwayBrowser/#/R-MMU-197958 FPGS-2 transforms THF to THFPG IEA Mus musculus 43474 R-MMU-198513 https://reactome.org/PathwayBrowser/#/R-MMU-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Mus musculus 43474 R-MMU-199425 https://reactome.org/PathwayBrowser/#/R-MMU-199425 PHLPP dephosphorylates S473 in AKT IEA Mus musculus 43474 R-MMU-199456 https://reactome.org/PathwayBrowser/#/R-MMU-199456 PTEN dephosphorylates PIP3 IEA Mus musculus 43474 R-MMU-199959 https://reactome.org/PathwayBrowser/#/R-MMU-199959 ERKs are inactivated by protein phosphatase 2A IEA Mus musculus 43474 R-MMU-200555 https://reactome.org/PathwayBrowser/#/R-MMU-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Mus musculus 43474 R-MMU-200681 https://reactome.org/PathwayBrowser/#/R-MMU-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Mus musculus 43474 R-MMU-200682 https://reactome.org/PathwayBrowser/#/R-MMU-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Mus musculus 43474 R-MMU-200711 https://reactome.org/PathwayBrowser/#/R-MMU-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Mus musculus 43474 R-MMU-201790 https://reactome.org/PathwayBrowser/#/R-MMU-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Mus musculus 43474 R-MMU-202214 https://reactome.org/PathwayBrowser/#/R-MMU-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Mus musculus 43474 R-MMU-202237 https://reactome.org/PathwayBrowser/#/R-MMU-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Mus musculus 43474 R-MMU-2023971 https://reactome.org/PathwayBrowser/#/R-MMU-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 43474 R-MMU-2023973 https://reactome.org/PathwayBrowser/#/R-MMU-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 43474 R-MMU-2029468 https://reactome.org/PathwayBrowser/#/R-MMU-2029468 Conversion of PA into DAG by PAP-1 IEA Mus musculus 43474 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus 43474 R-MMU-203797 https://reactome.org/PathwayBrowser/#/R-MMU-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Mus musculus 43474 R-MMU-203973 https://reactome.org/PathwayBrowser/#/R-MMU-203973 Vesicle budding IEA Mus musculus 43474 R-MMU-204169 https://reactome.org/PathwayBrowser/#/R-MMU-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Mus musculus 43474 R-MMU-2046093 https://reactome.org/PathwayBrowser/#/R-MMU-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Mus musculus 43474 R-MMU-209055 https://reactome.org/PathwayBrowser/#/R-MMU-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Mus musculus 43474 R-MMU-209096 https://reactome.org/PathwayBrowser/#/R-MMU-209096 Murine Axin1 is dephosphorylated by PP2A leading to reduced binding affinity with beta-catenin TAS Mus musculus 43474 R-MMU-210644 https://reactome.org/PathwayBrowser/#/R-MMU-210644 Phosphorylated STAT5A dimer is dephosphorylated by PTP1B TAS Mus musculus 43474 R-MMU-2130641 https://reactome.org/PathwayBrowser/#/R-MMU-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Mus musculus 43474 R-MMU-2130725 https://reactome.org/PathwayBrowser/#/R-MMU-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Mus musculus 43474 R-MMU-2161526 https://reactome.org/PathwayBrowser/#/R-MMU-2161526 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 43474 R-MMU-2161533 https://reactome.org/PathwayBrowser/#/R-MMU-2161533 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 43474 R-MMU-216723 https://reactome.org/PathwayBrowser/#/R-MMU-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Mus musculus 43474 R-MMU-216757 https://reactome.org/PathwayBrowser/#/R-MMU-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Mus musculus 43474 R-MMU-2187401 https://reactome.org/PathwayBrowser/#/R-MMU-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Mus musculus 43474 R-MMU-2395873 https://reactome.org/PathwayBrowser/#/R-MMU-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Mus musculus 43474 R-MMU-2395876 https://reactome.org/PathwayBrowser/#/R-MMU-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 43474 R-MMU-2395879 https://reactome.org/PathwayBrowser/#/R-MMU-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 43474 R-MMU-2395965 https://reactome.org/PathwayBrowser/#/R-MMU-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Mus musculus 43474 R-MMU-2408551 https://reactome.org/PathwayBrowser/#/R-MMU-2408551 SeMet is converted to AdoSeMet by MAT IEA Mus musculus 43474 R-MMU-2509793 https://reactome.org/PathwayBrowser/#/R-MMU-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Mus musculus 43474 R-MMU-2509816 https://reactome.org/PathwayBrowser/#/R-MMU-2509816 NUDT16 hydrolyses IDP to IMP IEA Mus musculus 43474 R-MMU-2529015 https://reactome.org/PathwayBrowser/#/R-MMU-2529015 Dephosphorylation of CK2-modified condensin I IEA Mus musculus 43474 R-MMU-2584246 https://reactome.org/PathwayBrowser/#/R-MMU-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Mus musculus 43474 R-MMU-265783 https://reactome.org/PathwayBrowser/#/R-MMU-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-266082 https://reactome.org/PathwayBrowser/#/R-MMU-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Mus musculus 43474 R-MMU-2682349 https://reactome.org/PathwayBrowser/#/R-MMU-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Mus musculus 43474 R-MMU-2730849 https://reactome.org/PathwayBrowser/#/R-MMU-2730849 Calcineurin binds and dephosphorylates NFAT IEA Mus musculus 43474 R-MMU-2872498 https://reactome.org/PathwayBrowser/#/R-MMU-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Mus musculus 43474 R-MMU-2995388 https://reactome.org/PathwayBrowser/#/R-MMU-2995388 PP2A dephosphorylates BANF1 IEA Mus musculus 43474 R-MMU-3002811 https://reactome.org/PathwayBrowser/#/R-MMU-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Mus musculus 43474 R-MMU-3095901 https://reactome.org/PathwayBrowser/#/R-MMU-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Mus musculus 43474 R-MMU-3257122 https://reactome.org/PathwayBrowser/#/R-MMU-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Mus musculus 43474 R-MMU-3262512 https://reactome.org/PathwayBrowser/#/R-MMU-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Mus musculus 43474 R-MMU-3266566 https://reactome.org/PathwayBrowser/#/R-MMU-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Mus musculus 43474 R-MMU-3371422 https://reactome.org/PathwayBrowser/#/R-MMU-3371422 ATP hydrolysis by HSP70 IEA Mus musculus 43474 R-MMU-3446785 https://reactome.org/PathwayBrowser/#/R-MMU-3446785 Ptpmt1 dephosphorylates PGP to PG TAS Mus musculus 43474 R-MMU-3697899 https://reactome.org/PathwayBrowser/#/R-MMU-3697899 Atp7a transfers Cu from Atox1 to Sod3 TAS Mus musculus 43474 R-MMU-372843 https://reactome.org/PathwayBrowser/#/R-MMU-372843 SLC25A10 mediates exchange of malate and phosphate IEA Mus musculus 43474 R-MMU-377643 https://reactome.org/PathwayBrowser/#/R-MMU-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Mus musculus 43474 R-MMU-3781018 https://reactome.org/PathwayBrowser/#/R-MMU-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Mus musculus 43474 R-MMU-380949 https://reactome.org/PathwayBrowser/#/R-MMU-380949 AMPK is dephosphorylated IEA Mus musculus 43474 R-MMU-380979 https://reactome.org/PathwayBrowser/#/R-MMU-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Mus musculus 43474 R-MMU-382553 https://reactome.org/PathwayBrowser/#/R-MMU-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Mus musculus 43474 R-MMU-382560 https://reactome.org/PathwayBrowser/#/R-MMU-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Mus musculus 43474 R-MMU-382575 https://reactome.org/PathwayBrowser/#/R-MMU-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Mus musculus 43474 R-MMU-383190 https://reactome.org/PathwayBrowser/#/R-MMU-383190 HCO3- transport through ion channel IEA Mus musculus 43474 R-MMU-390329 https://reactome.org/PathwayBrowser/#/R-MMU-390329 Dephosphorylation of AKT by PP2A IEA Mus musculus 43474 R-MMU-390593 https://reactome.org/PathwayBrowser/#/R-MMU-390593 ATP Hydrolysis By Myosin IEA Mus musculus 43474 R-MMU-4084976 https://reactome.org/PathwayBrowser/#/R-MMU-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Mus musculus 43474 R-MMU-4084989 https://reactome.org/PathwayBrowser/#/R-MMU-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Mus musculus 43474 R-MMU-4088141 https://reactome.org/PathwayBrowser/#/R-MMU-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Mus musculus 43474 R-MMU-4093339 https://reactome.org/PathwayBrowser/#/R-MMU-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Mus musculus 43474 R-MMU-416320 https://reactome.org/PathwayBrowser/#/R-MMU-416320 Trafficking of GluR1-containing AMPA receptors IEA Mus musculus 43474 R-MMU-416546 https://reactome.org/PathwayBrowser/#/R-MMU-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Mus musculus 43474 R-MMU-416559 https://reactome.org/PathwayBrowser/#/R-MMU-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Mus musculus 43474 R-MMU-416639 https://reactome.org/PathwayBrowser/#/R-MMU-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Mus musculus 43474 R-MMU-416985 https://reactome.org/PathwayBrowser/#/R-MMU-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Mus musculus 43474 R-MMU-421007 https://reactome.org/PathwayBrowser/#/R-MMU-421007 Endocytosis of Ca impermeable AMPA receptors IEA Mus musculus 43474 R-MMU-421142 https://reactome.org/PathwayBrowser/#/R-MMU-421142 Inactivation of R-Ras by Sema3A-Plexin-A1 GAP activity TAS Mus musculus 43474 R-MMU-421831 https://reactome.org/PathwayBrowser/#/R-MMU-421831 trans-Golgi Network Coat Assembly IEA Mus musculus 43474 R-MMU-421835 https://reactome.org/PathwayBrowser/#/R-MMU-421835 trans-Golgi Network Vesicle Scission IEA Mus musculus 43474 R-MMU-421836 https://reactome.org/PathwayBrowser/#/R-MMU-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Mus musculus 43474 R-MMU-427605 https://reactome.org/PathwayBrowser/#/R-MMU-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Mus musculus 43474 R-MMU-427645 https://reactome.org/PathwayBrowser/#/R-MMU-427645 SLC34A3 cotransports Pi, 2Na+ IEA Mus musculus 43474 R-MMU-427656 https://reactome.org/PathwayBrowser/#/R-MMU-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Mus musculus 43474 R-MMU-428609 https://reactome.org/PathwayBrowser/#/R-MMU-428609 Type I Na+-coupled phosphate co-transport IEA Mus musculus 43474 R-MMU-428664 https://reactome.org/PathwayBrowser/#/R-MMU-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Mus musculus 43474 R-MMU-428690 https://reactome.org/PathwayBrowser/#/R-MMU-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Mus musculus 43474 R-MMU-428696 https://reactome.org/PathwayBrowser/#/R-MMU-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Mus musculus 43474 R-MMU-429157 https://reactome.org/PathwayBrowser/#/R-MMU-429157 ABCC4 accumulation of dense granule contents IEA Mus musculus 43474 R-MMU-432688 https://reactome.org/PathwayBrowser/#/R-MMU-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating IEA Mus musculus 43474 R-MMU-432706 https://reactome.org/PathwayBrowser/#/R-MMU-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Mus musculus 43474 R-MMU-432707 https://reactome.org/PathwayBrowser/#/R-MMU-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Mus musculus 43474 R-MMU-4419948 https://reactome.org/PathwayBrowser/#/R-MMU-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Mus musculus 43474 R-MMU-445699 https://reactome.org/PathwayBrowser/#/R-MMU-445699 ATP Hydrolysis By Myosin IEA Mus musculus 43474 R-MMU-446200 https://reactome.org/PathwayBrowser/#/R-MMU-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Mus musculus 43474 R-MMU-449937 https://reactome.org/PathwayBrowser/#/R-MMU-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Mus musculus 43474 R-MMU-4551451 https://reactome.org/PathwayBrowser/#/R-MMU-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Mus musculus 43474 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 43474 R-MMU-504054 https://reactome.org/PathwayBrowser/#/R-MMU-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Mus musculus 43474 R-MMU-508040 https://reactome.org/PathwayBrowser/#/R-MMU-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Mus musculus 43474 R-MMU-508308 https://reactome.org/PathwayBrowser/#/R-MMU-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Mus musculus 43474 R-MMU-5221130 https://reactome.org/PathwayBrowser/#/R-MMU-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Mus musculus 43474 R-MMU-5223313 https://reactome.org/PathwayBrowser/#/R-MMU-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Mus musculus 43474 R-MMU-5223317 https://reactome.org/PathwayBrowser/#/R-MMU-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Mus musculus 43474 R-MMU-5251955 https://reactome.org/PathwayBrowser/#/R-MMU-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Mus musculus 43474 R-MMU-5251959 https://reactome.org/PathwayBrowser/#/R-MMU-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Mus musculus 43474 R-MMU-5251989 https://reactome.org/PathwayBrowser/#/R-MMU-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Mus musculus 43474 R-MMU-5419271 https://reactome.org/PathwayBrowser/#/R-MMU-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Mus musculus 43474 R-MMU-5419273 https://reactome.org/PathwayBrowser/#/R-MMU-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Mus musculus 43474 R-MMU-555065 https://reactome.org/PathwayBrowser/#/R-MMU-555065 Formation of clathrin coated vesicle IEA Mus musculus 43474 R-MMU-5603114 https://reactome.org/PathwayBrowser/#/R-MMU-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Mus musculus 43474 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 43474 R-MMU-5623513 https://reactome.org/PathwayBrowser/#/R-MMU-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Mus musculus 43474 R-MMU-5628905 https://reactome.org/PathwayBrowser/#/R-MMU-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Mus musculus 43474 R-MMU-5649705 https://reactome.org/PathwayBrowser/#/R-MMU-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Mus musculus 43474 R-MMU-5665809 https://reactome.org/PathwayBrowser/#/R-MMU-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Mus musculus 43474 R-MMU-5672957 https://reactome.org/PathwayBrowser/#/R-MMU-5672957 PP2A dephosphorylates KSR1 IEA Mus musculus 43474 R-MMU-5672961 https://reactome.org/PathwayBrowser/#/R-MMU-5672961 PP2A dephosphorylates inactive RAFs IEA Mus musculus 43474 R-MMU-5675373 https://reactome.org/PathwayBrowser/#/R-MMU-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Mus musculus 43474 R-MMU-5675376 https://reactome.org/PathwayBrowser/#/R-MMU-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Mus musculus 43474 R-MMU-5675431 https://reactome.org/PathwayBrowser/#/R-MMU-5675431 PP2A dephosphorylates RAF1 IEA Mus musculus 43474 R-MMU-5675433 https://reactome.org/PathwayBrowser/#/R-MMU-5675433 PP5 dephosphorylates RAF1 S338 IEA Mus musculus 43474 R-MMU-5678706 https://reactome.org/PathwayBrowser/#/R-MMU-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Mus musculus 43474 R-MMU-5678863 https://reactome.org/PathwayBrowser/#/R-MMU-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-5679041 https://reactome.org/PathwayBrowser/#/R-MMU-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-5682285 https://reactome.org/PathwayBrowser/#/R-MMU-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-5683405 https://reactome.org/PathwayBrowser/#/R-MMU-5683405 PPP5C dephosphorylates TP53BP1 IEA Mus musculus 43474 R-MMU-5683714 https://reactome.org/PathwayBrowser/#/R-MMU-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Mus musculus 43474 R-MMU-5683925 https://reactome.org/PathwayBrowser/#/R-MMU-5683925 ULK1 is dephosphorylated IEA Mus musculus 43474 R-MMU-5683967 https://reactome.org/PathwayBrowser/#/R-MMU-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Mus musculus 43474 R-MMU-5687758 https://reactome.org/PathwayBrowser/#/R-MMU-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Mus musculus 43474 R-MMU-5690996 https://reactome.org/PathwayBrowser/#/R-MMU-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Mus musculus 43474 R-MMU-5692462 https://reactome.org/PathwayBrowser/#/R-MMU-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Mus musculus 43474 R-MMU-5692480 https://reactome.org/PathwayBrowser/#/R-MMU-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Mus musculus 43474 R-MMU-5692754 https://reactome.org/PathwayBrowser/#/R-MMU-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Mus musculus 43474 R-MMU-5693153 https://reactome.org/PathwayBrowser/#/R-MMU-5693153 PPM1K dephosphorylates p-BCKDH IEA Mus musculus 43474 R-MMU-5694126 https://reactome.org/PathwayBrowser/#/R-MMU-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Mus musculus 43474 R-MMU-5694421 https://reactome.org/PathwayBrowser/#/R-MMU-5694421 PP6 dephosphorylates SEC24 IEA Mus musculus 43474 R-MMU-5694425 https://reactome.org/PathwayBrowser/#/R-MMU-5694425 NSF ATPase activity dissociates cis-SNARE IEA Mus musculus 43474 R-MMU-5694527 https://reactome.org/PathwayBrowser/#/R-MMU-5694527 Loss of SAR1B GTPase IEA Mus musculus 43474 R-MMU-5696408 https://reactome.org/PathwayBrowser/#/R-MMU-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Mus musculus 43474 R-MMU-5696415 https://reactome.org/PathwayBrowser/#/R-MMU-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Mus musculus 43474 R-MMU-5696839 https://reactome.org/PathwayBrowser/#/R-MMU-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Mus musculus 43474 R-MMU-6782131 https://reactome.org/PathwayBrowser/#/R-MMU-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Mus musculus 43474 R-MMU-6786245 https://reactome.org/PathwayBrowser/#/R-MMU-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Mus musculus 43474 R-MMU-6788295 https://reactome.org/PathwayBrowser/#/R-MMU-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Mus musculus 43474 R-MMU-6788912 https://reactome.org/PathwayBrowser/#/R-MMU-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Mus musculus 43474 R-MMU-6792863 https://reactome.org/PathwayBrowser/#/R-MMU-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Mus musculus 43474 R-MMU-6797630 https://reactome.org/PathwayBrowser/#/R-MMU-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Mus musculus 43474 R-MMU-6801342 https://reactome.org/PathwayBrowser/#/R-MMU-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Mus musculus 43474 R-MMU-6801456 https://reactome.org/PathwayBrowser/#/R-MMU-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Mus musculus 43474 R-MMU-6803545 https://reactome.org/PathwayBrowser/#/R-MMU-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Mus musculus 43474 R-MMU-6806967 https://reactome.org/PathwayBrowser/#/R-MMU-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Mus musculus 43474 R-MMU-6807008 https://reactome.org/PathwayBrowser/#/R-MMU-6807008 PTPRJ dephosphorylates MET IEA Mus musculus 43474 R-MMU-6807027 https://reactome.org/PathwayBrowser/#/R-MMU-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Mus musculus 43474 R-MMU-6809015 https://reactome.org/PathwayBrowser/#/R-MMU-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Mus musculus 43474 R-MMU-6809320 https://reactome.org/PathwayBrowser/#/R-MMU-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Mus musculus 43474 R-MMU-6809325 https://reactome.org/PathwayBrowser/#/R-MMU-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Mus musculus 43474 R-MMU-6809624 https://reactome.org/PathwayBrowser/#/R-MMU-6809624 I(1,3)P2 is dephosphorylated into I1P by Mtmr7 TAS Mus musculus 43474 R-MMU-6809627 https://reactome.org/PathwayBrowser/#/R-MMU-6809627 I(1,3)P2 is dephosphorylated into I1P by Mtmr7:Mtmr9 TAS Mus musculus 43474 R-MMU-6809720 https://reactome.org/PathwayBrowser/#/R-MMU-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Mus musculus 43474 R-MMU-6809777 https://reactome.org/PathwayBrowser/#/R-MMU-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Mus musculus 43474 R-MMU-6809778 https://reactome.org/PathwayBrowser/#/R-MMU-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Mus musculus 43474 R-MMU-6809945 https://reactome.org/PathwayBrowser/#/R-MMU-6809945 PI(3,5)P2 is dephosphorylated to PI5P by the Mtmr2:Sbf2 tetramer at the plasma membrane TAS Mus musculus 43474 R-MMU-6809977 https://reactome.org/PathwayBrowser/#/R-MMU-6809977 PI3P is dephosphorylated to PI by the Mtmr2:Sbf2 tetramer at the plasma membrane TAS Mus musculus 43474 R-MMU-6810410 https://reactome.org/PathwayBrowser/#/R-MMU-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Mus musculus 43474 R-MMU-6811422 https://reactome.org/PathwayBrowser/#/R-MMU-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Mus musculus 43474 R-MMU-6811504 https://reactome.org/PathwayBrowser/#/R-MMU-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Mus musculus 43474 R-MMU-6814120 https://reactome.org/PathwayBrowser/#/R-MMU-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Mus musculus 43474 R-MMU-68954 https://reactome.org/PathwayBrowser/#/R-MMU-68954 Mcm2-7 is phosphorylated by DDK IEA Mus musculus 43474 R-MMU-69199 https://reactome.org/PathwayBrowser/#/R-MMU-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Mus musculus 43474 R-MMU-70262 https://reactome.org/PathwayBrowser/#/R-MMU-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Mus musculus 43474 R-MMU-70449 https://reactome.org/PathwayBrowser/#/R-MMU-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Mus musculus 43474 R-MMU-70479 https://reactome.org/PathwayBrowser/#/R-MMU-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Mus musculus 43474 R-MMU-70482 https://reactome.org/PathwayBrowser/#/R-MMU-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Mus musculus 43474 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 43474 R-MMU-70555 https://reactome.org/PathwayBrowser/#/R-MMU-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Mus musculus 43474 R-MMU-70560 https://reactome.org/PathwayBrowser/#/R-MMU-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Mus musculus 43474 R-MMU-70606 https://reactome.org/PathwayBrowser/#/R-MMU-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Mus musculus 43474 R-MMU-70773 https://reactome.org/PathwayBrowser/#/R-MMU-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Mus musculus 43474 R-MMU-70997 https://reactome.org/PathwayBrowser/#/R-MMU-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Mus musculus 43474 R-MMU-71031 https://reactome.org/PathwayBrowser/#/R-MMU-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Mus musculus 43474 R-MMU-71732 https://reactome.org/PathwayBrowser/#/R-MMU-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Mus musculus 43474 R-MMU-71775 https://reactome.org/PathwayBrowser/#/R-MMU-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Mus musculus 43474 R-MMU-71825 https://reactome.org/PathwayBrowser/#/R-MMU-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Mus musculus 43474 R-MMU-72619 https://reactome.org/PathwayBrowser/#/R-MMU-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Mus musculus 43474 R-MMU-72621 https://reactome.org/PathwayBrowser/#/R-MMU-72621 Ribosomal scanning IEA Mus musculus 43474 R-MMU-72647 https://reactome.org/PathwayBrowser/#/R-MMU-72647 Cap-bound mRNA is activated by helicases IEA Mus musculus 43474 R-MMU-72671 https://reactome.org/PathwayBrowser/#/R-MMU-72671 eIF5B:GTP is hydrolyzed and released IEA Mus musculus 43474 R-MMU-73573 https://reactome.org/PathwayBrowser/#/R-MMU-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Mus musculus 43474 R-MMU-73577 https://reactome.org/PathwayBrowser/#/R-MMU-73577 CAD hexamer transforms L-Gln to CAP IEA Mus musculus 43474 R-MMU-73647 https://reactome.org/PathwayBrowser/#/R-MMU-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Mus musculus 43474 R-MMU-73805 https://reactome.org/PathwayBrowser/#/R-MMU-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Mus musculus 43474 R-MMU-73810 https://reactome.org/PathwayBrowser/#/R-MMU-73810 FGAM + ATP => AIR + ADP + Pi IEA Mus musculus 43474 R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 43474 R-MMU-73814 https://reactome.org/PathwayBrowser/#/R-MMU-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Mus musculus 43474 R-MMU-74242 https://reactome.org/PathwayBrowser/#/R-MMU-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Mus musculus 43474 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 43474 R-MMU-74249 https://reactome.org/PathwayBrowser/#/R-MMU-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Mus musculus 43474 R-MMU-74372 https://reactome.org/PathwayBrowser/#/R-MMU-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Mus musculus 43474 R-MMU-74376 https://reactome.org/PathwayBrowser/#/R-MMU-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Mus musculus 43474 R-MMU-74733 https://reactome.org/PathwayBrowser/#/R-MMU-74733 Insulin receptor de-phosphorylation IEA Mus musculus 43474 R-MMU-74948 https://reactome.org/PathwayBrowser/#/R-MMU-74948 PP2A dephosphorylates p-RHO to RHO IEA Mus musculus 43474 R-MMU-75848 https://reactome.org/PathwayBrowser/#/R-MMU-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Mus musculus 43474 R-MMU-75851 https://reactome.org/PathwayBrowser/#/R-MMU-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 43474 R-MMU-75899 https://reactome.org/PathwayBrowser/#/R-MMU-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Mus musculus 43474 R-MMU-75949 https://reactome.org/PathwayBrowser/#/R-MMU-75949 RNA Polymerase II Promoter Opening: First Transition IEA Mus musculus 43474 R-MMU-77078 https://reactome.org/PathwayBrowser/#/R-MMU-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Mus musculus 43474 R-MMU-877301 https://reactome.org/PathwayBrowser/#/R-MMU-877301 Dephosphorylation of Jaks by Ptps TAS Mus musculus 43474 R-MMU-8848053 https://reactome.org/PathwayBrowser/#/R-MMU-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Mus musculus 43474 R-MMU-8849082 https://reactome.org/PathwayBrowser/#/R-MMU-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Mus musculus 43474 R-MMU-8849435 https://reactome.org/PathwayBrowser/#/R-MMU-8849435 PTPN1 dephosphorylates PTK6 IEA Mus musculus 43474 R-MMU-8849969 https://reactome.org/PathwayBrowser/#/R-MMU-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Mus musculus 43474 R-MMU-8850846 https://reactome.org/PathwayBrowser/#/R-MMU-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Mus musculus 43474 R-MMU-8850854 https://reactome.org/PathwayBrowser/#/R-MMU-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Mus musculus 43474 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 43474 R-MMU-8851110 https://reactome.org/PathwayBrowser/#/R-MMU-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Mus musculus 43474 R-MMU-8851129 https://reactome.org/PathwayBrowser/#/R-MMU-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Mus musculus 43474 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 43474 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 43474 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 43474 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 43474 R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 43474 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 43474 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 43474 R-MMU-8852200 https://reactome.org/PathwayBrowser/#/R-MMU-8852200 Inactivation of LCK by PTPN22 IEA Mus musculus 43474 R-MMU-8854173 https://reactome.org/PathwayBrowser/#/R-MMU-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Mus musculus 43474 R-MMU-8854255 https://reactome.org/PathwayBrowser/#/R-MMU-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Mus musculus 43474 R-MMU-8854329 https://reactome.org/PathwayBrowser/#/R-MMU-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Mus musculus 43474 R-MMU-8854604 https://reactome.org/PathwayBrowser/#/R-MMU-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Mus musculus 43474 R-MMU-8854612 https://reactome.org/PathwayBrowser/#/R-MMU-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Mus musculus 43474 R-MMU-8855381 https://reactome.org/PathwayBrowser/#/R-MMU-8855381 PTPN22 dephosphorylates ZAP70 IEA Mus musculus 43474 R-MMU-8863804 https://reactome.org/PathwayBrowser/#/R-MMU-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Mus musculus 43474 R-MMU-8864029 https://reactome.org/PathwayBrowser/#/R-MMU-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Mus musculus 43474 R-MMU-8864036 https://reactome.org/PathwayBrowser/#/R-MMU-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Mus musculus 43474 R-MMU-8864125 https://reactome.org/PathwayBrowser/#/R-MMU-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Mus musculus 43474 R-MMU-8865774 https://reactome.org/PathwayBrowser/#/R-MMU-8865774 TTLLs polyglutamylate tubulin IEA Mus musculus 43474 R-MMU-8866542 https://reactome.org/PathwayBrowser/#/R-MMU-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Mus musculus 43474 R-MMU-8867047 https://reactome.org/PathwayBrowser/#/R-MMU-8867047 PTPN3 dephosphorylates EPS15 IEA Mus musculus 43474 R-MMU-8867370 https://reactome.org/PathwayBrowser/#/R-MMU-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Mus musculus 43474 R-MMU-8867658 https://reactome.org/PathwayBrowser/#/R-MMU-8867658 PTPN3 dephosphorylates MAPK12 IEA Mus musculus 43474 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 43474 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 43474 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 43474 R-MMU-8876889 https://reactome.org/PathwayBrowser/#/R-MMU-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 43474 R-MMU-8878654 https://reactome.org/PathwayBrowser/#/R-MMU-8878654 ACP6 hydrolyses MYS-LPA IEA Mus musculus 43474 R-MMU-8878787 https://reactome.org/PathwayBrowser/#/R-MMU-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Mus musculus 43474 R-MMU-8937767 https://reactome.org/PathwayBrowser/#/R-MMU-8937767 PTPN11 dephosphorylates RUNX1 IEA Mus musculus 43474 R-MMU-8940070 https://reactome.org/PathwayBrowser/#/R-MMU-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Mus musculus 43474 R-MMU-8940074 https://reactome.org/PathwayBrowser/#/R-MMU-8940074 NT5E:Zn2+ hydrolyses NMN IEA Mus musculus 43474 R-MMU-8951498 https://reactome.org/PathwayBrowser/#/R-MMU-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Mus musculus 43474 R-MMU-8952137 https://reactome.org/PathwayBrowser/#/R-MMU-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Mus musculus 43474 R-MMU-8953499 https://reactome.org/PathwayBrowser/#/R-MMU-8953499 IMPAD1 hydrolyses PAP to AMP IEA Mus musculus 43474 R-MMU-8959510 https://reactome.org/PathwayBrowser/#/R-MMU-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Mus musculus 43474 R-MMU-8981637 https://reactome.org/PathwayBrowser/#/R-MMU-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Mus musculus 43474 R-MMU-8982020 https://reactome.org/PathwayBrowser/#/R-MMU-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Mus musculus 43474 R-MMU-8982021 https://reactome.org/PathwayBrowser/#/R-MMU-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Mus musculus 43474 R-MMU-8982025 https://reactome.org/PathwayBrowser/#/R-MMU-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Mus musculus 43474 R-MMU-8985594 https://reactome.org/PathwayBrowser/#/R-MMU-8985594 MYO9B inactivates RHOA IEA Mus musculus 43474 R-MMU-9013022 https://reactome.org/PathwayBrowser/#/R-MMU-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Mus musculus 43474 R-MMU-9013111 https://reactome.org/PathwayBrowser/#/R-MMU-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Mus musculus 43474 R-MMU-9013144 https://reactome.org/PathwayBrowser/#/R-MMU-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Mus musculus 43474 R-MMU-9013161 https://reactome.org/PathwayBrowser/#/R-MMU-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Mus musculus 43474 R-MMU-9013437 https://reactome.org/PathwayBrowser/#/R-MMU-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Mus musculus 43474 R-MMU-9014295 https://reactome.org/PathwayBrowser/#/R-MMU-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Mus musculus 43474 R-MMU-9014434 https://reactome.org/PathwayBrowser/#/R-MMU-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Mus musculus 43474 R-MMU-9017488 https://reactome.org/PathwayBrowser/#/R-MMU-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Mus musculus 43474 R-MMU-9018745 https://reactome.org/PathwayBrowser/#/R-MMU-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Mus musculus 43474 R-MMU-9018806 https://reactome.org/PathwayBrowser/#/R-MMU-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Mus musculus 43474 R-MMU-9018814 https://reactome.org/PathwayBrowser/#/R-MMU-9018814 RHOT1 hydrolyzes GTP IEA Mus musculus 43474 R-MMU-9018826 https://reactome.org/PathwayBrowser/#/R-MMU-9018826 RHOT2 hydrolyzes GTP IEA Mus musculus 43474 R-MMU-9038161 https://reactome.org/PathwayBrowser/#/R-MMU-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Mus musculus 43474 R-MMU-917693 https://reactome.org/PathwayBrowser/#/R-MMU-917693 ESCRT Disassembly IEA Mus musculus 43474 R-MMU-917841 https://reactome.org/PathwayBrowser/#/R-MMU-917841 Acidification of Tf:TfR1 containing endosome IEA Mus musculus 43474 R-MMU-917979 https://reactome.org/PathwayBrowser/#/R-MMU-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-936802 https://reactome.org/PathwayBrowser/#/R-MMU-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Mus musculus 43474 R-MMU-936883 https://reactome.org/PathwayBrowser/#/R-MMU-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Mus musculus 43474 R-MMU-936895 https://reactome.org/PathwayBrowser/#/R-MMU-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Mus musculus 43474 R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 43474 R-MMU-937311 https://reactome.org/PathwayBrowser/#/R-MMU-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Mus musculus 43474 R-MMU-939763 https://reactome.org/PathwayBrowser/#/R-MMU-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Mus musculus 43474 R-MMU-947591 https://reactome.org/PathwayBrowser/#/R-MMU-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Mus musculus 43474 R-MMU-9610641 https://reactome.org/PathwayBrowser/#/R-MMU-9610641 Kif17 transports GluN1:GluN2B (Grin1:Grin2b) NMDA receptors to the plasma membrane TAS Mus musculus 43474 R-MMU-9624893 https://reactome.org/PathwayBrowser/#/R-MMU-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Mus musculus 43474 R-MMU-9635739 https://reactome.org/PathwayBrowser/#/R-MMU-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Mus musculus 43474 R-MMU-9640195 https://reactome.org/PathwayBrowser/#/R-MMU-9640195 RRAGA,B hydrolyzes GTP IEA Mus musculus 43474 R-MMU-9645598 https://reactome.org/PathwayBrowser/#/R-MMU-9645598 RRAGC,D hydrolyzes GTP IEA Mus musculus 43474 R-MMU-965067 https://reactome.org/PathwayBrowser/#/R-MMU-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Mus musculus 43474 R-MMU-9658445 https://reactome.org/PathwayBrowser/#/R-MMU-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Mus musculus 43474 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 43474 R-MMU-9661417 https://reactome.org/PathwayBrowser/#/R-MMU-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-9668419 https://reactome.org/PathwayBrowser/#/R-MMU-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Mus musculus 43474 R-MMU-9668464 https://reactome.org/PathwayBrowser/#/R-MMU-9668464 Atp2b2 (PMCA2) transports Ca2+ from the cytosol to the extracellular region TAS Mus musculus 43474 R-MMU-9674816 https://reactome.org/PathwayBrowser/#/R-MMU-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Mus musculus 43474 R-MMU-9684118 https://reactome.org/PathwayBrowser/#/R-MMU-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Mus musculus 43474 R-MMU-9686524 https://reactome.org/PathwayBrowser/#/R-MMU-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Mus musculus 43474 R-MMU-9693282 https://reactome.org/PathwayBrowser/#/R-MMU-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Mus musculus 43474 R-MMU-9698408 https://reactome.org/PathwayBrowser/#/R-MMU-9698408 PTPRJ dephosphorylates active FLT3 IEA Mus musculus 43474 R-MMU-9700200 https://reactome.org/PathwayBrowser/#/R-MMU-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Mus musculus 43474 R-MMU-9701507 https://reactome.org/PathwayBrowser/#/R-MMU-9701507 PTPN6 dephosphorylates JAK3 IEA Mus musculus 43474 R-MMU-9706399 https://reactome.org/PathwayBrowser/#/R-MMU-9706399 RHOBTB3 hydrolyzes ATP IEA Mus musculus 43474 R-MMU-9727198 https://reactome.org/PathwayBrowser/#/R-MMU-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Mus musculus 43474 R-MMU-9750546 https://reactome.org/PathwayBrowser/#/R-MMU-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-9750617 https://reactome.org/PathwayBrowser/#/R-MMU-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-9750656 https://reactome.org/PathwayBrowser/#/R-MMU-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Mus musculus 43474 R-MMU-9753278 https://reactome.org/PathwayBrowser/#/R-MMU-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 43474 R-MMU-9753283 https://reactome.org/PathwayBrowser/#/R-MMU-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 43474 R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 43474 R-MMU-9759206 https://reactome.org/PathwayBrowser/#/R-MMU-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Mus musculus 43474 R-MMU-9759454 https://reactome.org/PathwayBrowser/#/R-MMU-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Mus musculus 43474 R-MMU-9759461 https://reactome.org/PathwayBrowser/#/R-MMU-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Mus musculus 43474 R-MMU-9770141 https://reactome.org/PathwayBrowser/#/R-MMU-9770141 Formation of the Spliceosomal C* complex IEA Mus musculus 43474 R-MMU-9770142 https://reactome.org/PathwayBrowser/#/R-MMU-9770142 Formation of the Spliceosomal B complex IEA Mus musculus 43474 R-MMU-9770145 https://reactome.org/PathwayBrowser/#/R-MMU-9770145 Formation of the Spliceosomal Bact complex IEA Mus musculus 43474 R-MMU-977324 https://reactome.org/PathwayBrowser/#/R-MMU-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Mus musculus 43474 R-MMU-983144 https://reactome.org/PathwayBrowser/#/R-MMU-983144 Transport of Antigen peptide in to ER IEA Mus musculus 43474 R-MMU-9837419 https://reactome.org/PathwayBrowser/#/R-MMU-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Mus musculus 43474 R-MMU-9838004 https://reactome.org/PathwayBrowser/#/R-MMU-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Mus musculus 43474 R-MMU-9838081 https://reactome.org/PathwayBrowser/#/R-MMU-9838081 LONP1 degrades mitochondrial matrix proteins IEA Mus musculus 43474 R-MMU-9838289 https://reactome.org/PathwayBrowser/#/R-MMU-9838289 CLPXP degrades mitochondrial matrix proteins IEA Mus musculus 43474 R-MMU-9839059 https://reactome.org/PathwayBrowser/#/R-MMU-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Mus musculus 43474 R-MMU-9839105 https://reactome.org/PathwayBrowser/#/R-MMU-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Mus musculus 43474 R-MMU-9839113 https://reactome.org/PathwayBrowser/#/R-MMU-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Mus musculus 43474 R-MMU-9843721 https://reactome.org/PathwayBrowser/#/R-MMU-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Mus musculus 43474 R-MMU-9853385 https://reactome.org/PathwayBrowser/#/R-MMU-9853385 PPP1CC dephosphorylates PLK1 IEA Mus musculus 43474 R-MMU-9861725 https://reactome.org/PathwayBrowser/#/R-MMU-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Mus musculus 43474 R-MMU-997309 https://reactome.org/PathwayBrowser/#/R-MMU-997309 Dephosphorylation of STAT1 by SHP2 IEA Mus musculus 43474 R-MMU-997311 https://reactome.org/PathwayBrowser/#/R-MMU-997311 Dephosphorylation of TYK2 by PTP1B IEA Mus musculus 43474 R-MMU-997314 https://reactome.org/PathwayBrowser/#/R-MMU-997314 Dephosphorylation of JAK1 by SHP1 IEA Mus musculus 43474 R-MMU-997326 https://reactome.org/PathwayBrowser/#/R-MMU-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Mus musculus 43474 R-MTU-868608 https://reactome.org/PathwayBrowser/#/R-MTU-868608 Trehalose-6-phosphate is hydrolyzed to trehalose TAS Mycobacterium tuberculosis 43474 R-MTU-879274 https://reactome.org/PathwayBrowser/#/R-MTU-879274 acetylglucosamine-inositol-phosphate is dephosphorylated TAS Mycobacterium tuberculosis 43474 R-MTU-936583 https://reactome.org/PathwayBrowser/#/R-MTU-936583 APS is phosphorylated to PAPS TAS Mycobacterium tuberculosis 43474 R-MTU-936631 https://reactome.org/PathwayBrowser/#/R-MTU-936631 sulfate uptake in the cytosol TAS Mycobacterium tuberculosis 43474 R-MTU-936659 https://reactome.org/PathwayBrowser/#/R-MTU-936659 PAPS is dephosphorylated to APS TAS Mycobacterium tuberculosis 43474 R-MTU-936665 https://reactome.org/PathwayBrowser/#/R-MTU-936665 OPS is added to the carrier sulfide TAS Mycobacterium tuberculosis 43474 R-MTU-964884 https://reactome.org/PathwayBrowser/#/R-MTU-964884 Dephosphorylation of EPSP yields chorismate TAS Mycobacterium tuberculosis 43474 R-MTU-964886 https://reactome.org/PathwayBrowser/#/R-MTU-964886 EPSP from shikimate 3-phosphate TAS Mycobacterium tuberculosis 43474 R-MTU-964912 https://reactome.org/PathwayBrowser/#/R-MTU-964912 DHAP from Ery4P and PEP TAS Mycobacterium tuberculosis 43474 R-MTU-964914 https://reactome.org/PathwayBrowser/#/R-MTU-964914 DHQ from DAHP dephosphorylation TAS Mycobacterium tuberculosis 43474 R-NUL-1236944 https://reactome.org/PathwayBrowser/#/R-NUL-1236944 Translocation of antigenic peptides back to phagosomes via TAP TAS Gallus gallus 43474 R-NUL-2167872 https://reactome.org/PathwayBrowser/#/R-NUL-2167872 PP1CC dephosphorylates TGFBR1 TAS Homo sapiens 43474 R-NUL-391408 https://reactome.org/PathwayBrowser/#/R-NUL-391408 Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC TAS Mus musculus 43474 R-NUL-391437 https://reactome.org/PathwayBrowser/#/R-NUL-391437 Hydrolysis of ATP and release of folded actin from CCT/TriC TAS Bos taurus 43474 R-NUL-420388 https://reactome.org/PathwayBrowser/#/R-NUL-420388 Dephosphorylation of NCAM1 bound pFyn TAS Homo sapiens 43474 R-NUL-428519 https://reactome.org/PathwayBrowser/#/R-NUL-428519 Inactivation of Cdc42 TAS Rattus norvegicus 43474 R-NUL-8955873 https://reactome.org/PathwayBrowser/#/R-NUL-8955873 Polyglutamylase complex (Ttll1) polyglutamylates alpha subunits of tubulin TAS Homo sapiens 43474 R-NUL-9603754 https://reactome.org/PathwayBrowser/#/R-NUL-9603754 PTPRS dephosphorylates Ntrk3 TAS Gallus gallus 43474 R-NUL-9603766 https://reactome.org/PathwayBrowser/#/R-NUL-9603766 PTPRO dephosphorylate NTRK3 TAS Gallus gallus 43474 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 43474 R-PFA-111215 https://reactome.org/PathwayBrowser/#/R-PFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Plasmodium falciparum 43474 R-PFA-111524 https://reactome.org/PathwayBrowser/#/R-PFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Plasmodium falciparum 43474 R-PFA-1369028 https://reactome.org/PathwayBrowser/#/R-PFA-1369028 ABCAs mediate lipid efflux IEA Plasmodium falciparum 43474 R-PFA-1369052 https://reactome.org/PathwayBrowser/#/R-PFA-1369052 ABCAs mediate lipid influx IEA Plasmodium falciparum 43474 R-PFA-1369065 https://reactome.org/PathwayBrowser/#/R-PFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Plasmodium falciparum 43474 R-PFA-1454916 https://reactome.org/PathwayBrowser/#/R-PFA-1454916 The ABCC family mediates organic anion transport IEA Plasmodium falciparum 43474 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 43474 R-PFA-1467466 https://reactome.org/PathwayBrowser/#/R-PFA-1467466 ABCA4 mediates atRAL transport IEA Plasmodium falciparum 43474 R-PFA-1483203 https://reactome.org/PathwayBrowser/#/R-PFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Plasmodium falciparum 43474 R-PFA-1675824 https://reactome.org/PathwayBrowser/#/R-PFA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Plasmodium falciparum 43474 R-PFA-1675836 https://reactome.org/PathwayBrowser/#/R-PFA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Plasmodium falciparum 43474 R-PFA-1675949 https://reactome.org/PathwayBrowser/#/R-PFA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Plasmodium falciparum 43474 R-PFA-1675988 https://reactome.org/PathwayBrowser/#/R-PFA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Plasmodium falciparum 43474 R-PFA-1675994 https://reactome.org/PathwayBrowser/#/R-PFA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Plasmodium falciparum 43474 R-PFA-1676114 https://reactome.org/PathwayBrowser/#/R-PFA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Plasmodium falciparum 43474 R-PFA-1676124 https://reactome.org/PathwayBrowser/#/R-PFA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Plasmodium falciparum 43474 R-PFA-1676133 https://reactome.org/PathwayBrowser/#/R-PFA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Plasmodium falciparum 43474 R-PFA-1676177 https://reactome.org/PathwayBrowser/#/R-PFA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Plasmodium falciparum 43474 R-PFA-1676203 https://reactome.org/PathwayBrowser/#/R-PFA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Plasmodium falciparum 43474 R-PFA-174391 https://reactome.org/PathwayBrowser/#/R-PFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Plasmodium falciparum 43474 R-PFA-174394 https://reactome.org/PathwayBrowser/#/R-PFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Plasmodium falciparum 43474 R-PFA-1855174 https://reactome.org/PathwayBrowser/#/R-PFA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Plasmodium falciparum 43474 R-PFA-1855213 https://reactome.org/PathwayBrowser/#/R-PFA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Plasmodium falciparum 43474 R-PFA-1855218 https://reactome.org/PathwayBrowser/#/R-PFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Plasmodium falciparum 43474 R-PFA-1855222 https://reactome.org/PathwayBrowser/#/R-PFA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Plasmodium falciparum 43474 R-PFA-193362 https://reactome.org/PathwayBrowser/#/R-PFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Plasmodium falciparum 43474 R-PFA-196950 https://reactome.org/PathwayBrowser/#/R-PFA-196950 2xTRAP hydrolyzes FMN to RIB IEA Plasmodium falciparum 43474 R-PFA-200555 https://reactome.org/PathwayBrowser/#/R-PFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Plasmodium falciparum 43474 R-PFA-200711 https://reactome.org/PathwayBrowser/#/R-PFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Plasmodium falciparum 43474 R-PFA-203797 https://reactome.org/PathwayBrowser/#/R-PFA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Plasmodium falciparum 43474 R-PFA-2408551 https://reactome.org/PathwayBrowser/#/R-PFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Plasmodium falciparum 43474 R-PFA-2529015 https://reactome.org/PathwayBrowser/#/R-PFA-2529015 Dephosphorylation of CK2-modified condensin I IEA Plasmodium falciparum 43474 R-PFA-265783 https://reactome.org/PathwayBrowser/#/R-PFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Plasmodium falciparum 43474 R-PFA-3371422 https://reactome.org/PathwayBrowser/#/R-PFA-3371422 ATP hydrolysis by HSP70 IEA Plasmodium falciparum 43474 R-PFA-383190 https://reactome.org/PathwayBrowser/#/R-PFA-383190 HCO3- transport through ion channel IEA Plasmodium falciparum 43474 R-PFA-427605 https://reactome.org/PathwayBrowser/#/R-PFA-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 43474 R-PFA-429157 https://reactome.org/PathwayBrowser/#/R-PFA-429157 ABCC4 accumulation of dense granule contents IEA Plasmodium falciparum 43474 R-PFA-449937 https://reactome.org/PathwayBrowser/#/R-PFA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Plasmodium falciparum 43474 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 43474 R-PFA-504054 https://reactome.org/PathwayBrowser/#/R-PFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Plasmodium falciparum 43474 R-PFA-5221130 https://reactome.org/PathwayBrowser/#/R-PFA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Plasmodium falciparum 43474 R-PFA-5251959 https://reactome.org/PathwayBrowser/#/R-PFA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Plasmodium falciparum 43474 R-PFA-5251989 https://reactome.org/PathwayBrowser/#/R-PFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Plasmodium falciparum 43474 R-PFA-5675373 https://reactome.org/PathwayBrowser/#/R-PFA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Plasmodium falciparum 43474 R-PFA-5675376 https://reactome.org/PathwayBrowser/#/R-PFA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Plasmodium falciparum 43474 R-PFA-5675433 https://reactome.org/PathwayBrowser/#/R-PFA-5675433 PP5 dephosphorylates RAF1 S338 IEA Plasmodium falciparum 43474 R-PFA-5678706 https://reactome.org/PathwayBrowser/#/R-PFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Plasmodium falciparum 43474 R-PFA-5678863 https://reactome.org/PathwayBrowser/#/R-PFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Plasmodium falciparum 43474 R-PFA-5682285 https://reactome.org/PathwayBrowser/#/R-PFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Plasmodium falciparum 43474 R-PFA-5683714 https://reactome.org/PathwayBrowser/#/R-PFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Plasmodium falciparum 43474 R-PFA-5690996 https://reactome.org/PathwayBrowser/#/R-PFA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Plasmodium falciparum 43474 R-PFA-5692462 https://reactome.org/PathwayBrowser/#/R-PFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Plasmodium falciparum 43474 R-PFA-5692480 https://reactome.org/PathwayBrowser/#/R-PFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Plasmodium falciparum 43474 R-PFA-5694527 https://reactome.org/PathwayBrowser/#/R-PFA-5694527 Loss of SAR1B GTPase IEA Plasmodium falciparum 43474 R-PFA-5696839 https://reactome.org/PathwayBrowser/#/R-PFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Plasmodium falciparum 43474 R-PFA-6801342 https://reactome.org/PathwayBrowser/#/R-PFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Plasmodium falciparum 43474 R-PFA-6801456 https://reactome.org/PathwayBrowser/#/R-PFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Plasmodium falciparum 43474 R-PFA-6806967 https://reactome.org/PathwayBrowser/#/R-PFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Plasmodium falciparum 43474 R-PFA-6814120 https://reactome.org/PathwayBrowser/#/R-PFA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Plasmodium falciparum 43474 R-PFA-70449 https://reactome.org/PathwayBrowser/#/R-PFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Plasmodium falciparum 43474 R-PFA-70482 https://reactome.org/PathwayBrowser/#/R-PFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Plasmodium falciparum 43474 R-PFA-70997 https://reactome.org/PathwayBrowser/#/R-PFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Plasmodium falciparum 43474 R-PFA-71732 https://reactome.org/PathwayBrowser/#/R-PFA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Plasmodium falciparum 43474 R-PFA-71775 https://reactome.org/PathwayBrowser/#/R-PFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Plasmodium falciparum 43474 R-PFA-72621 https://reactome.org/PathwayBrowser/#/R-PFA-72621 Ribosomal scanning IEA Plasmodium falciparum 43474 R-PFA-72647 https://reactome.org/PathwayBrowser/#/R-PFA-72647 Cap-bound mRNA is activated by helicases IEA Plasmodium falciparum 43474 R-PFA-72671 https://reactome.org/PathwayBrowser/#/R-PFA-72671 eIF5B:GTP is hydrolyzed and released IEA Plasmodium falciparum 43474 R-PFA-73573 https://reactome.org/PathwayBrowser/#/R-PFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Plasmodium falciparum 43474 R-PFA-73577 https://reactome.org/PathwayBrowser/#/R-PFA-73577 CAD hexamer transforms L-Gln to CAP IEA Plasmodium falciparum 43474 R-PFA-73647 https://reactome.org/PathwayBrowser/#/R-PFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Plasmodium falciparum 43474 R-PFA-74372 https://reactome.org/PathwayBrowser/#/R-PFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Plasmodium falciparum 43474 R-PFA-74376 https://reactome.org/PathwayBrowser/#/R-PFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Plasmodium falciparum 43474 R-PFA-75851 https://reactome.org/PathwayBrowser/#/R-PFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 43474 R-PFA-75899 https://reactome.org/PathwayBrowser/#/R-PFA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Plasmodium falciparum 43474 R-PFA-77078 https://reactome.org/PathwayBrowser/#/R-PFA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Plasmodium falciparum 43474 R-PFA-8848053 https://reactome.org/PathwayBrowser/#/R-PFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Plasmodium falciparum 43474 R-PFA-8849969 https://reactome.org/PathwayBrowser/#/R-PFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Plasmodium falciparum 43474 R-PFA-8850846 https://reactome.org/PathwayBrowser/#/R-PFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 43474 R-PFA-8850854 https://reactome.org/PathwayBrowser/#/R-PFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 43474 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 43474 R-PFA-8851110 https://reactome.org/PathwayBrowser/#/R-PFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 43474 R-PFA-8851129 https://reactome.org/PathwayBrowser/#/R-PFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 43474 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 43474 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 43474 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 43474 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 43474 R-PFA-8854255 https://reactome.org/PathwayBrowser/#/R-PFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 43474 R-PFA-8854329 https://reactome.org/PathwayBrowser/#/R-PFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 43474 R-PFA-8865774 https://reactome.org/PathwayBrowser/#/R-PFA-8865774 TTLLs polyglutamylate tubulin IEA Plasmodium falciparum 43474 R-PFA-8876889 https://reactome.org/PathwayBrowser/#/R-PFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 43474 R-PFA-8959510 https://reactome.org/PathwayBrowser/#/R-PFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Plasmodium falciparum 43474 R-PFA-917841 https://reactome.org/PathwayBrowser/#/R-PFA-917841 Acidification of Tf:TfR1 containing endosome IEA Plasmodium falciparum 43474 R-PFA-917979 https://reactome.org/PathwayBrowser/#/R-PFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Plasmodium falciparum 43474 R-PFA-936883 https://reactome.org/PathwayBrowser/#/R-PFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Plasmodium falciparum 43474 R-PFA-936895 https://reactome.org/PathwayBrowser/#/R-PFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Plasmodium falciparum 43474 R-PFA-939763 https://reactome.org/PathwayBrowser/#/R-PFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Plasmodium falciparum 43474 R-PFA-947591 https://reactome.org/PathwayBrowser/#/R-PFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Plasmodium falciparum 43474 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 43474 R-PFA-9661417 https://reactome.org/PathwayBrowser/#/R-PFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Plasmodium falciparum 43474 R-PFA-9750546 https://reactome.org/PathwayBrowser/#/R-PFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Plasmodium falciparum 43474 R-PFA-9753278 https://reactome.org/PathwayBrowser/#/R-PFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 43474 R-PFA-9753283 https://reactome.org/PathwayBrowser/#/R-PFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 43474 R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 43474 R-PFA-9759454 https://reactome.org/PathwayBrowser/#/R-PFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Plasmodium falciparum 43474 R-PFA-9759461 https://reactome.org/PathwayBrowser/#/R-PFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Plasmodium falciparum 43474 R-PFA-9837419 https://reactome.org/PathwayBrowser/#/R-PFA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Plasmodium falciparum 43474 R-PFA-9839105 https://reactome.org/PathwayBrowser/#/R-PFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Plasmodium falciparum 43474 R-PFA-9843721 https://reactome.org/PathwayBrowser/#/R-PFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Plasmodium falciparum 43474 R-PFA-9853385 https://reactome.org/PathwayBrowser/#/R-PFA-9853385 PPP1CC dephosphorylates PLK1 IEA Plasmodium falciparum 43474 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 43474 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 43474 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 43474 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 43474 R-RNO-109415 https://reactome.org/PathwayBrowser/#/R-RNO-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Rattus norvegicus 43474 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 43474 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 43474 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 43474 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 43474 R-RNO-111215 https://reactome.org/PathwayBrowser/#/R-RNO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Rattus norvegicus 43474 R-RNO-111524 https://reactome.org/PathwayBrowser/#/R-RNO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Rattus norvegicus 43474 R-RNO-112033 https://reactome.org/PathwayBrowser/#/R-RNO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Rattus norvegicus 43474 R-RNO-112034 https://reactome.org/PathwayBrowser/#/R-RNO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Rattus norvegicus 43474 R-RNO-112037 https://reactome.org/PathwayBrowser/#/R-RNO-112037 Inactivation of PLC beta IEA Rattus norvegicus 43474 R-RNO-112265 https://reactome.org/PathwayBrowser/#/R-RNO-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Rattus norvegicus 43474 R-RNO-112266 https://reactome.org/PathwayBrowser/#/R-RNO-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Rattus norvegicus 43474 R-RNO-113503 https://reactome.org/PathwayBrowser/#/R-RNO-113503 PP2A mediated localization of RB1 protein in chromatin IEA Rattus norvegicus 43474 R-RNO-1169192 https://reactome.org/PathwayBrowser/#/R-RNO-1169192 PTP1B dephosphorylates GHR IEA Rattus norvegicus 43474 R-RNO-1237129 https://reactome.org/PathwayBrowser/#/R-RNO-1237129 Acireductone is created IEA Rattus norvegicus 43474 R-RNO-1237160 https://reactome.org/PathwayBrowser/#/R-RNO-1237160 MTA is cleaved and phosphorylated IEA Rattus norvegicus 43474 R-RNO-1247935 https://reactome.org/PathwayBrowser/#/R-RNO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Rattus norvegicus 43474 R-RNO-1295632 https://reactome.org/PathwayBrowser/#/R-RNO-1295632 PPA2A dephosphorylates SPRY2 IEA Rattus norvegicus 43474 R-RNO-1363274 https://reactome.org/PathwayBrowser/#/R-RNO-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Rattus norvegicus 43474 R-RNO-1363276 https://reactome.org/PathwayBrowser/#/R-RNO-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Rattus norvegicus 43474 R-RNO-1369028 https://reactome.org/PathwayBrowser/#/R-RNO-1369028 ABCAs mediate lipid efflux IEA Rattus norvegicus 43474 R-RNO-1369052 https://reactome.org/PathwayBrowser/#/R-RNO-1369052 ABCAs mediate lipid influx IEA Rattus norvegicus 43474 R-RNO-1369065 https://reactome.org/PathwayBrowser/#/R-RNO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Rattus norvegicus 43474 R-RNO-139906 https://reactome.org/PathwayBrowser/#/R-RNO-139906 Activation of BAD by calcineurin IEA Rattus norvegicus 43474 R-RNO-1454916 https://reactome.org/PathwayBrowser/#/R-RNO-1454916 The ABCC family mediates organic anion transport IEA Rattus norvegicus 43474 R-RNO-1454928 https://reactome.org/PathwayBrowser/#/R-RNO-1454928 ABCG4 may mediate cholesterol efflux IEA Rattus norvegicus 43474 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-1483096 https://reactome.org/PathwayBrowser/#/R-RNO-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Rattus norvegicus 43474 R-RNO-1483159 https://reactome.org/PathwayBrowser/#/R-RNO-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Rattus norvegicus 43474 R-RNO-1483203 https://reactome.org/PathwayBrowser/#/R-RNO-1483203 PA is dephosphorylated to DAG by LPIN IEA Rattus norvegicus 43474 R-RNO-159101 https://reactome.org/PathwayBrowser/#/R-RNO-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Rattus norvegicus 43474 R-RNO-163120 https://reactome.org/PathwayBrowser/#/R-RNO-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Rattus norvegicus 43474 R-RNO-163398 https://reactome.org/PathwayBrowser/#/R-RNO-163398 phosphorylated HSL + H2O -> HSL + orthophosphate TAS Rattus norvegicus 43474 R-RNO-163609 https://reactome.org/PathwayBrowser/#/R-RNO-163609 phosphorylated perilipin + H2O -> perilipin + orthophosphate TAS Rattus norvegicus 43474 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus 43474 R-RNO-164832 https://reactome.org/PathwayBrowser/#/R-RNO-164832 ATPase synthesizes ATP IEA Rattus norvegicus 43474 R-RNO-164840 https://reactome.org/PathwayBrowser/#/R-RNO-164840 ADP and Pi bind to ATPase IEA Rattus norvegicus 43474 R-RNO-1675795 https://reactome.org/PathwayBrowser/#/R-RNO-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Rattus norvegicus 43474 R-RNO-1675824 https://reactome.org/PathwayBrowser/#/R-RNO-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Rattus norvegicus 43474 R-RNO-1675836 https://reactome.org/PathwayBrowser/#/R-RNO-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-1675949 https://reactome.org/PathwayBrowser/#/R-RNO-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-1675988 https://reactome.org/PathwayBrowser/#/R-RNO-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-1675994 https://reactome.org/PathwayBrowser/#/R-RNO-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-1676005 https://reactome.org/PathwayBrowser/#/R-RNO-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Rattus norvegicus 43474 R-RNO-1676020 https://reactome.org/PathwayBrowser/#/R-RNO-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Rattus norvegicus 43474 R-RNO-1676065 https://reactome.org/PathwayBrowser/#/R-RNO-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Rattus norvegicus 43474 R-RNO-1676105 https://reactome.org/PathwayBrowser/#/R-RNO-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Rattus norvegicus 43474 R-RNO-1676114 https://reactome.org/PathwayBrowser/#/R-RNO-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Rattus norvegicus 43474 R-RNO-1676124 https://reactome.org/PathwayBrowser/#/R-RNO-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Rattus norvegicus 43474 R-RNO-1676133 https://reactome.org/PathwayBrowser/#/R-RNO-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Rattus norvegicus 43474 R-RNO-1676141 https://reactome.org/PathwayBrowser/#/R-RNO-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Rattus norvegicus 43474 R-RNO-1676149 https://reactome.org/PathwayBrowser/#/R-RNO-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-1676162 https://reactome.org/PathwayBrowser/#/R-RNO-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Rattus norvegicus 43474 R-RNO-1676164 https://reactome.org/PathwayBrowser/#/R-RNO-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-1676174 https://reactome.org/PathwayBrowser/#/R-RNO-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Rattus norvegicus 43474 R-RNO-1676177 https://reactome.org/PathwayBrowser/#/R-RNO-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-1676203 https://reactome.org/PathwayBrowser/#/R-RNO-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-1676204 https://reactome.org/PathwayBrowser/#/R-RNO-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Rattus norvegicus 43474 R-RNO-170153 https://reactome.org/PathwayBrowser/#/R-RNO-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Rattus norvegicus 43474 R-RNO-170158 https://reactome.org/PathwayBrowser/#/R-RNO-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Rattus norvegicus 43474 R-RNO-170161 https://reactome.org/PathwayBrowser/#/R-RNO-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Rattus norvegicus 43474 R-RNO-170666 https://reactome.org/PathwayBrowser/#/R-RNO-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Rattus norvegicus 43474 R-RNO-170685 https://reactome.org/PathwayBrowser/#/R-RNO-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Rattus norvegicus 43474 R-RNO-170686 https://reactome.org/PathwayBrowser/#/R-RNO-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Rattus norvegicus 43474 R-RNO-174110 https://reactome.org/PathwayBrowser/#/R-RNO-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Rattus norvegicus 43474 R-RNO-174367 https://reactome.org/PathwayBrowser/#/R-RNO-174367 GCL ligates L-Glu to L-Cys IEA Rattus norvegicus 43474 R-RNO-174391 https://reactome.org/PathwayBrowser/#/R-RNO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Rattus norvegicus 43474 R-RNO-174394 https://reactome.org/PathwayBrowser/#/R-RNO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Rattus norvegicus 43474 R-RNO-174438 https://reactome.org/PathwayBrowser/#/R-RNO-174438 Formation of the Flap Intermediate on the C-strand IEA Rattus norvegicus 43474 R-RNO-174439 https://reactome.org/PathwayBrowser/#/R-RNO-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Rattus norvegicus 43474 R-RNO-176606 https://reactome.org/PathwayBrowser/#/R-RNO-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Rattus norvegicus 43474 R-RNO-177923 https://reactome.org/PathwayBrowser/#/R-RNO-177923 Sustained activation of SRC kinase by SHP2 IEA Rattus norvegicus 43474 R-RNO-177924 https://reactome.org/PathwayBrowser/#/R-RNO-177924 Dephosphorylation of Gab1 by SHP2 IEA Rattus norvegicus 43474 R-RNO-177926 https://reactome.org/PathwayBrowser/#/R-RNO-177926 Dephosphorylation of PAG by SHP2 IEA Rattus norvegicus 43474 R-RNO-177935 https://reactome.org/PathwayBrowser/#/R-RNO-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Rattus norvegicus 43474 R-RNO-182041 https://reactome.org/PathwayBrowser/#/R-RNO-182041 Endocytosis of clathrin-coated vesicle TAS Rattus norvegicus 43474 R-RNO-1855154 https://reactome.org/PathwayBrowser/#/R-RNO-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855159 https://reactome.org/PathwayBrowser/#/R-RNO-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855163 https://reactome.org/PathwayBrowser/#/R-RNO-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Rattus norvegicus 43474 R-RNO-1855165 https://reactome.org/PathwayBrowser/#/R-RNO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855166 https://reactome.org/PathwayBrowser/#/R-RNO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855171 https://reactome.org/PathwayBrowser/#/R-RNO-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855174 https://reactome.org/PathwayBrowser/#/R-RNO-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855180 https://reactome.org/PathwayBrowser/#/R-RNO-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855198 https://reactome.org/PathwayBrowser/#/R-RNO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855200 https://reactome.org/PathwayBrowser/#/R-RNO-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Rattus norvegicus 43474 R-RNO-1855202 https://reactome.org/PathwayBrowser/#/R-RNO-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855205 https://reactome.org/PathwayBrowser/#/R-RNO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855208 https://reactome.org/PathwayBrowser/#/R-RNO-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855210 https://reactome.org/PathwayBrowser/#/R-RNO-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855211 https://reactome.org/PathwayBrowser/#/R-RNO-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855213 https://reactome.org/PathwayBrowser/#/R-RNO-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-1855218 https://reactome.org/PathwayBrowser/#/R-RNO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855219 https://reactome.org/PathwayBrowser/#/R-RNO-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 43474 R-RNO-1855222 https://reactome.org/PathwayBrowser/#/R-RNO-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-1855225 https://reactome.org/PathwayBrowser/#/R-RNO-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Rattus norvegicus 43474 R-RNO-1855232 https://reactome.org/PathwayBrowser/#/R-RNO-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Rattus norvegicus 43474 R-RNO-1861595 https://reactome.org/PathwayBrowser/#/R-RNO-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Rattus norvegicus 43474 R-RNO-191414 https://reactome.org/PathwayBrowser/#/R-RNO-191414 MVD decarboxylates MVA5PP to IPPP IEA Rattus norvegicus 43474 R-RNO-193362 https://reactome.org/PathwayBrowser/#/R-RNO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-194153 https://reactome.org/PathwayBrowser/#/R-RNO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-196950 https://reactome.org/PathwayBrowser/#/R-RNO-196950 2xTRAP hydrolyzes FMN to RIB IEA Rattus norvegicus 43474 R-RNO-197958 https://reactome.org/PathwayBrowser/#/R-RNO-197958 FPGS-2 transforms THF to THFPG IEA Rattus norvegicus 43474 R-RNO-198513 https://reactome.org/PathwayBrowser/#/R-RNO-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Rattus norvegicus 43474 R-RNO-199425 https://reactome.org/PathwayBrowser/#/R-RNO-199425 PHLPP dephosphorylates S473 in AKT IEA Rattus norvegicus 43474 R-RNO-199456 https://reactome.org/PathwayBrowser/#/R-RNO-199456 PTEN dephosphorylates PIP3 IEA Rattus norvegicus 43474 R-RNO-199959 https://reactome.org/PathwayBrowser/#/R-RNO-199959 ERKs are inactivated by protein phosphatase 2A IEA Rattus norvegicus 43474 R-RNO-200555 https://reactome.org/PathwayBrowser/#/R-RNO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Rattus norvegicus 43474 R-RNO-200681 https://reactome.org/PathwayBrowser/#/R-RNO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Rattus norvegicus 43474 R-RNO-200682 https://reactome.org/PathwayBrowser/#/R-RNO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Rattus norvegicus 43474 R-RNO-200711 https://reactome.org/PathwayBrowser/#/R-RNO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Rattus norvegicus 43474 R-RNO-201760 https://reactome.org/PathwayBrowser/#/R-RNO-201760 Ppp3 complex dephosphorylates DARPP-32 on T34 TAS Rattus norvegicus 43474 R-RNO-201790 https://reactome.org/PathwayBrowser/#/R-RNO-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Rattus norvegicus 43474 R-RNO-202214 https://reactome.org/PathwayBrowser/#/R-RNO-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Rattus norvegicus 43474 R-RNO-202237 https://reactome.org/PathwayBrowser/#/R-RNO-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Rattus norvegicus 43474 R-RNO-2023971 https://reactome.org/PathwayBrowser/#/R-RNO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 43474 R-RNO-2023973 https://reactome.org/PathwayBrowser/#/R-RNO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 43474 R-RNO-2029468 https://reactome.org/PathwayBrowser/#/R-RNO-2029468 Conversion of PA into DAG by PAP-1 IEA Rattus norvegicus 43474 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus 43474 R-RNO-203797 https://reactome.org/PathwayBrowser/#/R-RNO-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Rattus norvegicus 43474 R-RNO-203973 https://reactome.org/PathwayBrowser/#/R-RNO-203973 Vesicle budding IEA Rattus norvegicus 43474 R-RNO-204169 https://reactome.org/PathwayBrowser/#/R-RNO-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Rattus norvegicus 43474 R-RNO-2046093 https://reactome.org/PathwayBrowser/#/R-RNO-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Rattus norvegicus 43474 R-RNO-209055 https://reactome.org/PathwayBrowser/#/R-RNO-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Rattus norvegicus 43474 R-RNO-2130641 https://reactome.org/PathwayBrowser/#/R-RNO-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Rattus norvegicus 43474 R-RNO-2130725 https://reactome.org/PathwayBrowser/#/R-RNO-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Rattus norvegicus 43474 R-RNO-216723 https://reactome.org/PathwayBrowser/#/R-RNO-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 43474 R-RNO-216757 https://reactome.org/PathwayBrowser/#/R-RNO-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 43474 R-RNO-2187401 https://reactome.org/PathwayBrowser/#/R-RNO-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Rattus norvegicus 43474 R-RNO-2395873 https://reactome.org/PathwayBrowser/#/R-RNO-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Rattus norvegicus 43474 R-RNO-2395876 https://reactome.org/PathwayBrowser/#/R-RNO-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 43474 R-RNO-2395879 https://reactome.org/PathwayBrowser/#/R-RNO-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 43474 R-RNO-2395965 https://reactome.org/PathwayBrowser/#/R-RNO-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Rattus norvegicus 43474 R-RNO-2408551 https://reactome.org/PathwayBrowser/#/R-RNO-2408551 SeMet is converted to AdoSeMet by MAT IEA Rattus norvegicus 43474 R-RNO-2509793 https://reactome.org/PathwayBrowser/#/R-RNO-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Rattus norvegicus 43474 R-RNO-2509816 https://reactome.org/PathwayBrowser/#/R-RNO-2509816 NUDT16 hydrolyses IDP to IMP IEA Rattus norvegicus 43474 R-RNO-2529015 https://reactome.org/PathwayBrowser/#/R-RNO-2529015 Dephosphorylation of CK2-modified condensin I IEA Rattus norvegicus 43474 R-RNO-2584246 https://reactome.org/PathwayBrowser/#/R-RNO-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Rattus norvegicus 43474 R-RNO-265783 https://reactome.org/PathwayBrowser/#/R-RNO-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-266082 https://reactome.org/PathwayBrowser/#/R-RNO-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Rattus norvegicus 43474 R-RNO-2682349 https://reactome.org/PathwayBrowser/#/R-RNO-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Rattus norvegicus 43474 R-RNO-2730849 https://reactome.org/PathwayBrowser/#/R-RNO-2730849 Calcineurin binds and dephosphorylates NFAT IEA Rattus norvegicus 43474 R-RNO-2872498 https://reactome.org/PathwayBrowser/#/R-RNO-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Rattus norvegicus 43474 R-RNO-2995388 https://reactome.org/PathwayBrowser/#/R-RNO-2995388 PP2A dephosphorylates BANF1 IEA Rattus norvegicus 43474 R-RNO-3002811 https://reactome.org/PathwayBrowser/#/R-RNO-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Rattus norvegicus 43474 R-RNO-3095901 https://reactome.org/PathwayBrowser/#/R-RNO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Rattus norvegicus 43474 R-RNO-3257122 https://reactome.org/PathwayBrowser/#/R-RNO-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Rattus norvegicus 43474 R-RNO-3262512 https://reactome.org/PathwayBrowser/#/R-RNO-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Rattus norvegicus 43474 R-RNO-3371422 https://reactome.org/PathwayBrowser/#/R-RNO-3371422 ATP hydrolysis by HSP70 IEA Rattus norvegicus 43474 R-RNO-372843 https://reactome.org/PathwayBrowser/#/R-RNO-372843 SLC25A10 mediates exchange of malate and phosphate IEA Rattus norvegicus 43474 R-RNO-377643 https://reactome.org/PathwayBrowser/#/R-RNO-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Rattus norvegicus 43474 R-RNO-3781018 https://reactome.org/PathwayBrowser/#/R-RNO-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Rattus norvegicus 43474 R-RNO-380949 https://reactome.org/PathwayBrowser/#/R-RNO-380949 AMPK is dephosphorylated IEA Rattus norvegicus 43474 R-RNO-380979 https://reactome.org/PathwayBrowser/#/R-RNO-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Rattus norvegicus 43474 R-RNO-382553 https://reactome.org/PathwayBrowser/#/R-RNO-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Rattus norvegicus 43474 R-RNO-382560 https://reactome.org/PathwayBrowser/#/R-RNO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Rattus norvegicus 43474 R-RNO-382575 https://reactome.org/PathwayBrowser/#/R-RNO-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Rattus norvegicus 43474 R-RNO-383190 https://reactome.org/PathwayBrowser/#/R-RNO-383190 HCO3- transport through ion channel IEA Rattus norvegicus 43474 R-RNO-390329 https://reactome.org/PathwayBrowser/#/R-RNO-390329 Dephosphorylation of AKT by PP2A IEA Rattus norvegicus 43474 R-RNO-390593 https://reactome.org/PathwayBrowser/#/R-RNO-390593 ATP Hydrolysis By Myosin IEA Rattus norvegicus 43474 R-RNO-4084976 https://reactome.org/PathwayBrowser/#/R-RNO-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Rattus norvegicus 43474 R-RNO-4084989 https://reactome.org/PathwayBrowser/#/R-RNO-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Rattus norvegicus 43474 R-RNO-4088141 https://reactome.org/PathwayBrowser/#/R-RNO-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Rattus norvegicus 43474 R-RNO-4093339 https://reactome.org/PathwayBrowser/#/R-RNO-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Rattus norvegicus 43474 R-RNO-416320 https://reactome.org/PathwayBrowser/#/R-RNO-416320 Trafficking of GluR1-containing AMPA receptors IEA Rattus norvegicus 43474 R-RNO-416546 https://reactome.org/PathwayBrowser/#/R-RNO-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Rattus norvegicus 43474 R-RNO-416559 https://reactome.org/PathwayBrowser/#/R-RNO-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Rattus norvegicus 43474 R-RNO-416639 https://reactome.org/PathwayBrowser/#/R-RNO-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Rattus norvegicus 43474 R-RNO-416985 https://reactome.org/PathwayBrowser/#/R-RNO-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Rattus norvegicus 43474 R-RNO-421007 https://reactome.org/PathwayBrowser/#/R-RNO-421007 Endocytosis of Ca impermeable AMPA receptors IEA Rattus norvegicus 43474 R-RNO-421831 https://reactome.org/PathwayBrowser/#/R-RNO-421831 trans-Golgi Network Coat Assembly IEA Rattus norvegicus 43474 R-RNO-421835 https://reactome.org/PathwayBrowser/#/R-RNO-421835 trans-Golgi Network Vesicle Scission IEA Rattus norvegicus 43474 R-RNO-421836 https://reactome.org/PathwayBrowser/#/R-RNO-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Rattus norvegicus 43474 R-RNO-427605 https://reactome.org/PathwayBrowser/#/R-RNO-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Rattus norvegicus 43474 R-RNO-427645 https://reactome.org/PathwayBrowser/#/R-RNO-427645 SLC34A3 cotransports Pi, 2Na+ IEA Rattus norvegicus 43474 R-RNO-427656 https://reactome.org/PathwayBrowser/#/R-RNO-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Rattus norvegicus 43474 R-RNO-428609 https://reactome.org/PathwayBrowser/#/R-RNO-428609 Type I Na+-coupled phosphate co-transport IEA Rattus norvegicus 43474 R-RNO-428664 https://reactome.org/PathwayBrowser/#/R-RNO-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Rattus norvegicus 43474 R-RNO-428690 https://reactome.org/PathwayBrowser/#/R-RNO-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Rattus norvegicus 43474 R-RNO-428696 https://reactome.org/PathwayBrowser/#/R-RNO-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Rattus norvegicus 43474 R-RNO-429157 https://reactome.org/PathwayBrowser/#/R-RNO-429157 ABCC4 accumulation of dense granule contents IEA Rattus norvegicus 43474 R-RNO-432688 https://reactome.org/PathwayBrowser/#/R-RNO-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating IEA Rattus norvegicus 43474 R-RNO-432706 https://reactome.org/PathwayBrowser/#/R-RNO-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Rattus norvegicus 43474 R-RNO-432707 https://reactome.org/PathwayBrowser/#/R-RNO-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Rattus norvegicus 43474 R-RNO-4419948 https://reactome.org/PathwayBrowser/#/R-RNO-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Rattus norvegicus 43474 R-RNO-446200 https://reactome.org/PathwayBrowser/#/R-RNO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Rattus norvegicus 43474 R-RNO-449937 https://reactome.org/PathwayBrowser/#/R-RNO-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Rattus norvegicus 43474 R-RNO-4551451 https://reactome.org/PathwayBrowser/#/R-RNO-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Rattus norvegicus 43474 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 43474 R-RNO-504054 https://reactome.org/PathwayBrowser/#/R-RNO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Rattus norvegicus 43474 R-RNO-508040 https://reactome.org/PathwayBrowser/#/R-RNO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Rattus norvegicus 43474 R-RNO-508308 https://reactome.org/PathwayBrowser/#/R-RNO-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Rattus norvegicus 43474 R-RNO-5221130 https://reactome.org/PathwayBrowser/#/R-RNO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Rattus norvegicus 43474 R-RNO-5223317 https://reactome.org/PathwayBrowser/#/R-RNO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Rattus norvegicus 43474 R-RNO-5251955 https://reactome.org/PathwayBrowser/#/R-RNO-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Rattus norvegicus 43474 R-RNO-5251959 https://reactome.org/PathwayBrowser/#/R-RNO-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Rattus norvegicus 43474 R-RNO-5251989 https://reactome.org/PathwayBrowser/#/R-RNO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Rattus norvegicus 43474 R-RNO-5333610 https://reactome.org/PathwayBrowser/#/R-RNO-5333610 Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec-tRNA(Sec):Eefsec:GTP is hydrolysed to Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec and Eefsec:GDP by Eefsec TAS Rattus norvegicus 43474 R-RNO-5419271 https://reactome.org/PathwayBrowser/#/R-RNO-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Rattus norvegicus 43474 R-RNO-5419273 https://reactome.org/PathwayBrowser/#/R-RNO-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Rattus norvegicus 43474 R-RNO-555065 https://reactome.org/PathwayBrowser/#/R-RNO-555065 Formation of clathrin coated vesicle IEA Rattus norvegicus 43474 R-RNO-5603114 https://reactome.org/PathwayBrowser/#/R-RNO-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Rattus norvegicus 43474 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 43474 R-RNO-5623513 https://reactome.org/PathwayBrowser/#/R-RNO-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Rattus norvegicus 43474 R-RNO-5628905 https://reactome.org/PathwayBrowser/#/R-RNO-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Rattus norvegicus 43474 R-RNO-5649705 https://reactome.org/PathwayBrowser/#/R-RNO-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Rattus norvegicus 43474 R-RNO-5665809 https://reactome.org/PathwayBrowser/#/R-RNO-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Rattus norvegicus 43474 R-RNO-5672957 https://reactome.org/PathwayBrowser/#/R-RNO-5672957 PP2A dephosphorylates KSR1 IEA Rattus norvegicus 43474 R-RNO-5672961 https://reactome.org/PathwayBrowser/#/R-RNO-5672961 PP2A dephosphorylates inactive RAFs IEA Rattus norvegicus 43474 R-RNO-5675373 https://reactome.org/PathwayBrowser/#/R-RNO-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Rattus norvegicus 43474 R-RNO-5675376 https://reactome.org/PathwayBrowser/#/R-RNO-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Rattus norvegicus 43474 R-RNO-5675431 https://reactome.org/PathwayBrowser/#/R-RNO-5675431 PP2A dephosphorylates RAF1 IEA Rattus norvegicus 43474 R-RNO-5675433 https://reactome.org/PathwayBrowser/#/R-RNO-5675433 PP5 dephosphorylates RAF1 S338 IEA Rattus norvegicus 43474 R-RNO-5678706 https://reactome.org/PathwayBrowser/#/R-RNO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Rattus norvegicus 43474 R-RNO-5678863 https://reactome.org/PathwayBrowser/#/R-RNO-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-5679041 https://reactome.org/PathwayBrowser/#/R-RNO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-5682285 https://reactome.org/PathwayBrowser/#/R-RNO-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-5683405 https://reactome.org/PathwayBrowser/#/R-RNO-5683405 PPP5C dephosphorylates TP53BP1 IEA Rattus norvegicus 43474 R-RNO-5683714 https://reactome.org/PathwayBrowser/#/R-RNO-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Rattus norvegicus 43474 R-RNO-5683925 https://reactome.org/PathwayBrowser/#/R-RNO-5683925 ULK1 is dephosphorylated IEA Rattus norvegicus 43474 R-RNO-5683967 https://reactome.org/PathwayBrowser/#/R-RNO-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Rattus norvegicus 43474 R-RNO-5687758 https://reactome.org/PathwayBrowser/#/R-RNO-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Rattus norvegicus 43474 R-RNO-5690996 https://reactome.org/PathwayBrowser/#/R-RNO-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Rattus norvegicus 43474 R-RNO-5692462 https://reactome.org/PathwayBrowser/#/R-RNO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Rattus norvegicus 43474 R-RNO-5692480 https://reactome.org/PathwayBrowser/#/R-RNO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Rattus norvegicus 43474 R-RNO-5692754 https://reactome.org/PathwayBrowser/#/R-RNO-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Rattus norvegicus 43474 R-RNO-5693153 https://reactome.org/PathwayBrowser/#/R-RNO-5693153 PPM1K dephosphorylates p-BCKDH IEA Rattus norvegicus 43474 R-RNO-5694126 https://reactome.org/PathwayBrowser/#/R-RNO-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Rattus norvegicus 43474 R-RNO-5694421 https://reactome.org/PathwayBrowser/#/R-RNO-5694421 PP6 dephosphorylates SEC24 IEA Rattus norvegicus 43474 R-RNO-5694425 https://reactome.org/PathwayBrowser/#/R-RNO-5694425 NSF ATPase activity dissociates cis-SNARE IEA Rattus norvegicus 43474 R-RNO-5694527 https://reactome.org/PathwayBrowser/#/R-RNO-5694527 Loss of SAR1B GTPase IEA Rattus norvegicus 43474 R-RNO-5696408 https://reactome.org/PathwayBrowser/#/R-RNO-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Rattus norvegicus 43474 R-RNO-5696415 https://reactome.org/PathwayBrowser/#/R-RNO-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Rattus norvegicus 43474 R-RNO-5696839 https://reactome.org/PathwayBrowser/#/R-RNO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Rattus norvegicus 43474 R-RNO-6782131 https://reactome.org/PathwayBrowser/#/R-RNO-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus 43474 R-RNO-6786245 https://reactome.org/PathwayBrowser/#/R-RNO-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Rattus norvegicus 43474 R-RNO-6788295 https://reactome.org/PathwayBrowser/#/R-RNO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Rattus norvegicus 43474 R-RNO-6788912 https://reactome.org/PathwayBrowser/#/R-RNO-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Rattus norvegicus 43474 R-RNO-6792863 https://reactome.org/PathwayBrowser/#/R-RNO-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Rattus norvegicus 43474 R-RNO-6797630 https://reactome.org/PathwayBrowser/#/R-RNO-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Rattus norvegicus 43474 R-RNO-6801342 https://reactome.org/PathwayBrowser/#/R-RNO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Rattus norvegicus 43474 R-RNO-6801456 https://reactome.org/PathwayBrowser/#/R-RNO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Rattus norvegicus 43474 R-RNO-6803545 https://reactome.org/PathwayBrowser/#/R-RNO-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Rattus norvegicus 43474 R-RNO-6806967 https://reactome.org/PathwayBrowser/#/R-RNO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Rattus norvegicus 43474 R-RNO-6807008 https://reactome.org/PathwayBrowser/#/R-RNO-6807008 PTPRJ dephosphorylates MET IEA Rattus norvegicus 43474 R-RNO-6807027 https://reactome.org/PathwayBrowser/#/R-RNO-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Rattus norvegicus 43474 R-RNO-6809015 https://reactome.org/PathwayBrowser/#/R-RNO-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Rattus norvegicus 43474 R-RNO-6809320 https://reactome.org/PathwayBrowser/#/R-RNO-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-6809325 https://reactome.org/PathwayBrowser/#/R-RNO-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Rattus norvegicus 43474 R-RNO-6809720 https://reactome.org/PathwayBrowser/#/R-RNO-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Rattus norvegicus 43474 R-RNO-6809777 https://reactome.org/PathwayBrowser/#/R-RNO-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Rattus norvegicus 43474 R-RNO-6809778 https://reactome.org/PathwayBrowser/#/R-RNO-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Rattus norvegicus 43474 R-RNO-6810410 https://reactome.org/PathwayBrowser/#/R-RNO-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Rattus norvegicus 43474 R-RNO-6811422 https://reactome.org/PathwayBrowser/#/R-RNO-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Rattus norvegicus 43474 R-RNO-6811504 https://reactome.org/PathwayBrowser/#/R-RNO-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Rattus norvegicus 43474 R-RNO-6814120 https://reactome.org/PathwayBrowser/#/R-RNO-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Rattus norvegicus 43474 R-RNO-68954 https://reactome.org/PathwayBrowser/#/R-RNO-68954 Mcm2-7 is phosphorylated by DDK IEA Rattus norvegicus 43474 R-RNO-69199 https://reactome.org/PathwayBrowser/#/R-RNO-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Rattus norvegicus 43474 R-RNO-70262 https://reactome.org/PathwayBrowser/#/R-RNO-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Rattus norvegicus 43474 R-RNO-70449 https://reactome.org/PathwayBrowser/#/R-RNO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Rattus norvegicus 43474 R-RNO-70479 https://reactome.org/PathwayBrowser/#/R-RNO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Rattus norvegicus 43474 R-RNO-70482 https://reactome.org/PathwayBrowser/#/R-RNO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Rattus norvegicus 43474 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 43474 R-RNO-70555 https://reactome.org/PathwayBrowser/#/R-RNO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Rattus norvegicus 43474 R-RNO-70560 https://reactome.org/PathwayBrowser/#/R-RNO-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Rattus norvegicus 43474 R-RNO-70606 https://reactome.org/PathwayBrowser/#/R-RNO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Rattus norvegicus 43474 R-RNO-70773 https://reactome.org/PathwayBrowser/#/R-RNO-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Rattus norvegicus 43474 R-RNO-70997 https://reactome.org/PathwayBrowser/#/R-RNO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Rattus norvegicus 43474 R-RNO-71031 https://reactome.org/PathwayBrowser/#/R-RNO-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Rattus norvegicus 43474 R-RNO-71732 https://reactome.org/PathwayBrowser/#/R-RNO-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Rattus norvegicus 43474 R-RNO-71775 https://reactome.org/PathwayBrowser/#/R-RNO-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Rattus norvegicus 43474 R-RNO-71825 https://reactome.org/PathwayBrowser/#/R-RNO-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Rattus norvegicus 43474 R-RNO-72621 https://reactome.org/PathwayBrowser/#/R-RNO-72621 Ribosomal scanning IEA Rattus norvegicus 43474 R-RNO-72671 https://reactome.org/PathwayBrowser/#/R-RNO-72671 eIF5B:GTP is hydrolyzed and released IEA Rattus norvegicus 43474 R-RNO-73573 https://reactome.org/PathwayBrowser/#/R-RNO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Rattus norvegicus 43474 R-RNO-73577 https://reactome.org/PathwayBrowser/#/R-RNO-73577 CAD hexamer transforms L-Gln to CAP IEA Rattus norvegicus 43474 R-RNO-73647 https://reactome.org/PathwayBrowser/#/R-RNO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Rattus norvegicus 43474 R-RNO-73805 https://reactome.org/PathwayBrowser/#/R-RNO-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Rattus norvegicus 43474 R-RNO-73810 https://reactome.org/PathwayBrowser/#/R-RNO-73810 FGAM + ATP => AIR + ADP + Pi IEA Rattus norvegicus 43474 R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 43474 R-RNO-73814 https://reactome.org/PathwayBrowser/#/R-RNO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Rattus norvegicus 43474 R-RNO-74242 https://reactome.org/PathwayBrowser/#/R-RNO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Rattus norvegicus 43474 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 43474 R-RNO-74249 https://reactome.org/PathwayBrowser/#/R-RNO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Rattus norvegicus 43474 R-RNO-74372 https://reactome.org/PathwayBrowser/#/R-RNO-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Rattus norvegicus 43474 R-RNO-74376 https://reactome.org/PathwayBrowser/#/R-RNO-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Rattus norvegicus 43474 R-RNO-74733 https://reactome.org/PathwayBrowser/#/R-RNO-74733 Insulin receptor de-phosphorylation IEA Rattus norvegicus 43474 R-RNO-74948 https://reactome.org/PathwayBrowser/#/R-RNO-74948 PP2A dephosphorylates p-RHO to RHO IEA Rattus norvegicus 43474 R-RNO-75848 https://reactome.org/PathwayBrowser/#/R-RNO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Rattus norvegicus 43474 R-RNO-75851 https://reactome.org/PathwayBrowser/#/R-RNO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 43474 R-RNO-75899 https://reactome.org/PathwayBrowser/#/R-RNO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Rattus norvegicus 43474 R-RNO-75949 https://reactome.org/PathwayBrowser/#/R-RNO-75949 RNA Polymerase II Promoter Opening: First Transition IEA Rattus norvegicus 43474 R-RNO-77078 https://reactome.org/PathwayBrowser/#/R-RNO-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Rattus norvegicus 43474 R-RNO-8848053 https://reactome.org/PathwayBrowser/#/R-RNO-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Rattus norvegicus 43474 R-RNO-8849082 https://reactome.org/PathwayBrowser/#/R-RNO-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Rattus norvegicus 43474 R-RNO-8849435 https://reactome.org/PathwayBrowser/#/R-RNO-8849435 PTPN1 dephosphorylates PTK6 IEA Rattus norvegicus 43474 R-RNO-8849969 https://reactome.org/PathwayBrowser/#/R-RNO-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Rattus norvegicus 43474 R-RNO-8850846 https://reactome.org/PathwayBrowser/#/R-RNO-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 43474 R-RNO-8850854 https://reactome.org/PathwayBrowser/#/R-RNO-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 43474 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 43474 R-RNO-8851110 https://reactome.org/PathwayBrowser/#/R-RNO-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 43474 R-RNO-8851129 https://reactome.org/PathwayBrowser/#/R-RNO-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 43474 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 43474 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 43474 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 43474 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 43474 R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 43474 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 43474 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 43474 R-RNO-8852200 https://reactome.org/PathwayBrowser/#/R-RNO-8852200 Inactivation of LCK by PTPN22 IEA Rattus norvegicus 43474 R-RNO-8854173 https://reactome.org/PathwayBrowser/#/R-RNO-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Rattus norvegicus 43474 R-RNO-8854255 https://reactome.org/PathwayBrowser/#/R-RNO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 43474 R-RNO-8854329 https://reactome.org/PathwayBrowser/#/R-RNO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 43474 R-RNO-8854604 https://reactome.org/PathwayBrowser/#/R-RNO-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Rattus norvegicus 43474 R-RNO-8854612 https://reactome.org/PathwayBrowser/#/R-RNO-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Rattus norvegicus 43474 R-RNO-8855381 https://reactome.org/PathwayBrowser/#/R-RNO-8855381 PTPN22 dephosphorylates ZAP70 IEA Rattus norvegicus 43474 R-RNO-8863804 https://reactome.org/PathwayBrowser/#/R-RNO-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Rattus norvegicus 43474 R-RNO-8864029 https://reactome.org/PathwayBrowser/#/R-RNO-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Rattus norvegicus 43474 R-RNO-8864036 https://reactome.org/PathwayBrowser/#/R-RNO-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Rattus norvegicus 43474 R-RNO-8864125 https://reactome.org/PathwayBrowser/#/R-RNO-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Rattus norvegicus 43474 R-RNO-8865774 https://reactome.org/PathwayBrowser/#/R-RNO-8865774 TTLLs polyglutamylate tubulin IEA Rattus norvegicus 43474 R-RNO-8866542 https://reactome.org/PathwayBrowser/#/R-RNO-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Rattus norvegicus 43474 R-RNO-8867047 https://reactome.org/PathwayBrowser/#/R-RNO-8867047 PTPN3 dephosphorylates EPS15 IEA Rattus norvegicus 43474 R-RNO-8867370 https://reactome.org/PathwayBrowser/#/R-RNO-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Rattus norvegicus 43474 R-RNO-8867658 https://reactome.org/PathwayBrowser/#/R-RNO-8867658 PTPN3 dephosphorylates MAPK12 IEA Rattus norvegicus 43474 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 43474 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 43474 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 43474 R-RNO-8876889 https://reactome.org/PathwayBrowser/#/R-RNO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 43474 R-RNO-8878654 https://reactome.org/PathwayBrowser/#/R-RNO-8878654 ACP6 hydrolyses MYS-LPA IEA Rattus norvegicus 43474 R-RNO-8878787 https://reactome.org/PathwayBrowser/#/R-RNO-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Rattus norvegicus 43474 R-RNO-8937767 https://reactome.org/PathwayBrowser/#/R-RNO-8937767 PTPN11 dephosphorylates RUNX1 IEA Rattus norvegicus 43474 R-RNO-8940070 https://reactome.org/PathwayBrowser/#/R-RNO-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Rattus norvegicus 43474 R-RNO-8940074 https://reactome.org/PathwayBrowser/#/R-RNO-8940074 NT5E:Zn2+ hydrolyses NMN IEA Rattus norvegicus 43474 R-RNO-8951498 https://reactome.org/PathwayBrowser/#/R-RNO-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Rattus norvegicus 43474 R-RNO-8952137 https://reactome.org/PathwayBrowser/#/R-RNO-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Rattus norvegicus 43474 R-RNO-8953499 https://reactome.org/PathwayBrowser/#/R-RNO-8953499 IMPAD1 hydrolyses PAP to AMP IEA Rattus norvegicus 43474 R-RNO-8955775 https://reactome.org/PathwayBrowser/#/R-RNO-8955775 Pgp:Mg2+ dimer hydrolyses 3PG to glycerol TAS Rattus norvegicus 43474 R-RNO-8959510 https://reactome.org/PathwayBrowser/#/R-RNO-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Rattus norvegicus 43474 R-RNO-8981637 https://reactome.org/PathwayBrowser/#/R-RNO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Rattus norvegicus 43474 R-RNO-8982020 https://reactome.org/PathwayBrowser/#/R-RNO-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Rattus norvegicus 43474 R-RNO-8982021 https://reactome.org/PathwayBrowser/#/R-RNO-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Rattus norvegicus 43474 R-RNO-8982025 https://reactome.org/PathwayBrowser/#/R-RNO-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Rattus norvegicus 43474 R-RNO-8985594 https://reactome.org/PathwayBrowser/#/R-RNO-8985594 MYO9B inactivates RHOA IEA Rattus norvegicus 43474 R-RNO-9013022 https://reactome.org/PathwayBrowser/#/R-RNO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Rattus norvegicus 43474 R-RNO-9013144 https://reactome.org/PathwayBrowser/#/R-RNO-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Rattus norvegicus 43474 R-RNO-9013161 https://reactome.org/PathwayBrowser/#/R-RNO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Rattus norvegicus 43474 R-RNO-9013437 https://reactome.org/PathwayBrowser/#/R-RNO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Rattus norvegicus 43474 R-RNO-9014295 https://reactome.org/PathwayBrowser/#/R-RNO-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Rattus norvegicus 43474 R-RNO-9014434 https://reactome.org/PathwayBrowser/#/R-RNO-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Rattus norvegicus 43474 R-RNO-9017488 https://reactome.org/PathwayBrowser/#/R-RNO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Rattus norvegicus 43474 R-RNO-9018745 https://reactome.org/PathwayBrowser/#/R-RNO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Rattus norvegicus 43474 R-RNO-9018826 https://reactome.org/PathwayBrowser/#/R-RNO-9018826 RHOT2 hydrolyzes GTP IEA Rattus norvegicus 43474 R-RNO-9038161 https://reactome.org/PathwayBrowser/#/R-RNO-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Rattus norvegicus 43474 R-RNO-917693 https://reactome.org/PathwayBrowser/#/R-RNO-917693 ESCRT Disassembly IEA Rattus norvegicus 43474 R-RNO-917841 https://reactome.org/PathwayBrowser/#/R-RNO-917841 Acidification of Tf:TfR1 containing endosome IEA Rattus norvegicus 43474 R-RNO-917979 https://reactome.org/PathwayBrowser/#/R-RNO-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-936802 https://reactome.org/PathwayBrowser/#/R-RNO-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Rattus norvegicus 43474 R-RNO-936883 https://reactome.org/PathwayBrowser/#/R-RNO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Rattus norvegicus 43474 R-RNO-936895 https://reactome.org/PathwayBrowser/#/R-RNO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Rattus norvegicus 43474 R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 43474 R-RNO-937311 https://reactome.org/PathwayBrowser/#/R-RNO-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 43474 R-RNO-939763 https://reactome.org/PathwayBrowser/#/R-RNO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Rattus norvegicus 43474 R-RNO-947591 https://reactome.org/PathwayBrowser/#/R-RNO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Rattus norvegicus 43474 R-RNO-9619441 https://reactome.org/PathwayBrowser/#/R-RNO-9619441 Ppm1e dephosphorylates Camk4 TAS Rattus norvegicus 43474 R-RNO-9619459 https://reactome.org/PathwayBrowser/#/R-RNO-9619459 Ppm1f dephosphorylates p-T286-CaMKII-alpha TAS Rattus norvegicus 43474 R-RNO-9619472 https://reactome.org/PathwayBrowser/#/R-RNO-9619472 Ppm1f dephosphorylates Camk1 TAS Rattus norvegicus 43474 R-RNO-9624893 https://reactome.org/PathwayBrowser/#/R-RNO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Rattus norvegicus 43474 R-RNO-9635739 https://reactome.org/PathwayBrowser/#/R-RNO-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Rattus norvegicus 43474 R-RNO-9640195 https://reactome.org/PathwayBrowser/#/R-RNO-9640195 RRAGA,B hydrolyzes GTP IEA Rattus norvegicus 43474 R-RNO-9645598 https://reactome.org/PathwayBrowser/#/R-RNO-9645598 RRAGC,D hydrolyzes GTP IEA Rattus norvegicus 43474 R-RNO-965067 https://reactome.org/PathwayBrowser/#/R-RNO-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Rattus norvegicus 43474 R-RNO-9658445 https://reactome.org/PathwayBrowser/#/R-RNO-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Rattus norvegicus 43474 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 43474 R-RNO-9661417 https://reactome.org/PathwayBrowser/#/R-RNO-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-9664221 https://reactome.org/PathwayBrowser/#/R-RNO-9664221 Atp2b1 (Pmca1) transports Ca2+ from the cytosol to the extracellular region TAS Rattus norvegicus 43474 R-RNO-9664232 https://reactome.org/PathwayBrowser/#/R-RNO-9664232 Atp2b2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region TAS Rattus norvegicus 43474 R-RNO-9668419 https://reactome.org/PathwayBrowser/#/R-RNO-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Rattus norvegicus 43474 R-RNO-9674816 https://reactome.org/PathwayBrowser/#/R-RNO-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Rattus norvegicus 43474 R-RNO-9684118 https://reactome.org/PathwayBrowser/#/R-RNO-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus 43474 R-RNO-9686524 https://reactome.org/PathwayBrowser/#/R-RNO-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Rattus norvegicus 43474 R-RNO-9693282 https://reactome.org/PathwayBrowser/#/R-RNO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Rattus norvegicus 43474 R-RNO-9700200 https://reactome.org/PathwayBrowser/#/R-RNO-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Rattus norvegicus 43474 R-RNO-9701507 https://reactome.org/PathwayBrowser/#/R-RNO-9701507 PTPN6 dephosphorylates JAK3 IEA Rattus norvegicus 43474 R-RNO-9706399 https://reactome.org/PathwayBrowser/#/R-RNO-9706399 RHOBTB3 hydrolyzes ATP IEA Rattus norvegicus 43474 R-RNO-9727198 https://reactome.org/PathwayBrowser/#/R-RNO-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 43474 R-RNO-9750546 https://reactome.org/PathwayBrowser/#/R-RNO-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-9750617 https://reactome.org/PathwayBrowser/#/R-RNO-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-9750656 https://reactome.org/PathwayBrowser/#/R-RNO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Rattus norvegicus 43474 R-RNO-9753278 https://reactome.org/PathwayBrowser/#/R-RNO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 43474 R-RNO-9753283 https://reactome.org/PathwayBrowser/#/R-RNO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 43474 R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 43474 R-RNO-9759454 https://reactome.org/PathwayBrowser/#/R-RNO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Rattus norvegicus 43474 R-RNO-9759461 https://reactome.org/PathwayBrowser/#/R-RNO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Rattus norvegicus 43474 R-RNO-9770141 https://reactome.org/PathwayBrowser/#/R-RNO-9770141 Formation of the Spliceosomal C* complex IEA Rattus norvegicus 43474 R-RNO-9770142 https://reactome.org/PathwayBrowser/#/R-RNO-9770142 Formation of the Spliceosomal B complex IEA Rattus norvegicus 43474 R-RNO-977324 https://reactome.org/PathwayBrowser/#/R-RNO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Rattus norvegicus 43474 R-RNO-983144 https://reactome.org/PathwayBrowser/#/R-RNO-983144 Transport of Antigen peptide in to ER IEA Rattus norvegicus 43474 R-RNO-9837419 https://reactome.org/PathwayBrowser/#/R-RNO-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Rattus norvegicus 43474 R-RNO-9838004 https://reactome.org/PathwayBrowser/#/R-RNO-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Rattus norvegicus 43474 R-RNO-9838081 https://reactome.org/PathwayBrowser/#/R-RNO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Rattus norvegicus 43474 R-RNO-9838289 https://reactome.org/PathwayBrowser/#/R-RNO-9838289 CLPXP degrades mitochondrial matrix proteins IEA Rattus norvegicus 43474 R-RNO-9839059 https://reactome.org/PathwayBrowser/#/R-RNO-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Rattus norvegicus 43474 R-RNO-9839105 https://reactome.org/PathwayBrowser/#/R-RNO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Rattus norvegicus 43474 R-RNO-9839113 https://reactome.org/PathwayBrowser/#/R-RNO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Rattus norvegicus 43474 R-RNO-9843721 https://reactome.org/PathwayBrowser/#/R-RNO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Rattus norvegicus 43474 R-RNO-9853385 https://reactome.org/PathwayBrowser/#/R-RNO-9853385 PPP1CC dephosphorylates PLK1 IEA Rattus norvegicus 43474 R-RNO-9861725 https://reactome.org/PathwayBrowser/#/R-RNO-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Rattus norvegicus 43474 R-RNO-997309 https://reactome.org/PathwayBrowser/#/R-RNO-997309 Dephosphorylation of STAT1 by SHP2 IEA Rattus norvegicus 43474 R-RNO-997311 https://reactome.org/PathwayBrowser/#/R-RNO-997311 Dephosphorylation of TYK2 by PTP1B IEA Rattus norvegicus 43474 R-RNO-997314 https://reactome.org/PathwayBrowser/#/R-RNO-997314 Dephosphorylation of JAK1 by SHP1 IEA Rattus norvegicus 43474 R-RNO-997326 https://reactome.org/PathwayBrowser/#/R-RNO-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Rattus norvegicus 43474 R-SCE-111215 https://reactome.org/PathwayBrowser/#/R-SCE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Saccharomyces cerevisiae 43474 R-SCE-111524 https://reactome.org/PathwayBrowser/#/R-SCE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Saccharomyces cerevisiae 43474 R-SCE-112033 https://reactome.org/PathwayBrowser/#/R-SCE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Saccharomyces cerevisiae 43474 R-SCE-112034 https://reactome.org/PathwayBrowser/#/R-SCE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Saccharomyces cerevisiae 43474 R-SCE-112037 https://reactome.org/PathwayBrowser/#/R-SCE-112037 Inactivation of PLC beta IEA Saccharomyces cerevisiae 43474 R-SCE-1237129 https://reactome.org/PathwayBrowser/#/R-SCE-1237129 Acireductone is created IEA Saccharomyces cerevisiae 43474 R-SCE-1237160 https://reactome.org/PathwayBrowser/#/R-SCE-1237160 MTA is cleaved and phosphorylated IEA Saccharomyces cerevisiae 43474 R-SCE-1247935 https://reactome.org/PathwayBrowser/#/R-SCE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Saccharomyces cerevisiae 43474 R-SCE-1252253 https://reactome.org/PathwayBrowser/#/R-SCE-1252253 TIM23 PAM complex translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix TAS Saccharomyces cerevisiae 43474 R-SCE-141687 https://reactome.org/PathwayBrowser/#/R-SCE-141687 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex TAS Saccharomyces cerevisiae 43474 R-SCE-1454916 https://reactome.org/PathwayBrowser/#/R-SCE-1454916 The ABCC family mediates organic anion transport IEA Saccharomyces cerevisiae 43474 R-SCE-1454928 https://reactome.org/PathwayBrowser/#/R-SCE-1454928 ABCG4 may mediate cholesterol efflux IEA Saccharomyces cerevisiae 43474 R-SCE-1483203 https://reactome.org/PathwayBrowser/#/R-SCE-1483203 PA is dephosphorylated to DAG by LPIN IEA Saccharomyces cerevisiae 43474 R-SCE-164832 https://reactome.org/PathwayBrowser/#/R-SCE-164832 ATPase synthesizes ATP IEA Saccharomyces cerevisiae 43474 R-SCE-164840 https://reactome.org/PathwayBrowser/#/R-SCE-164840 ADP and Pi bind to ATPase IEA Saccharomyces cerevisiae 43474 R-SCE-1675795 https://reactome.org/PathwayBrowser/#/R-SCE-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1675836 https://reactome.org/PathwayBrowser/#/R-SCE-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1675949 https://reactome.org/PathwayBrowser/#/R-SCE-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1675988 https://reactome.org/PathwayBrowser/#/R-SCE-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1675994 https://reactome.org/PathwayBrowser/#/R-SCE-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1676065 https://reactome.org/PathwayBrowser/#/R-SCE-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1676105 https://reactome.org/PathwayBrowser/#/R-SCE-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1676114 https://reactome.org/PathwayBrowser/#/R-SCE-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1676124 https://reactome.org/PathwayBrowser/#/R-SCE-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1676133 https://reactome.org/PathwayBrowser/#/R-SCE-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1676141 https://reactome.org/PathwayBrowser/#/R-SCE-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1676149 https://reactome.org/PathwayBrowser/#/R-SCE-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1676177 https://reactome.org/PathwayBrowser/#/R-SCE-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1676203 https://reactome.org/PathwayBrowser/#/R-SCE-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Saccharomyces cerevisiae 43474 R-SCE-1676204 https://reactome.org/PathwayBrowser/#/R-SCE-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Saccharomyces cerevisiae 43474 R-SCE-174391 https://reactome.org/PathwayBrowser/#/R-SCE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Saccharomyces cerevisiae 43474 R-SCE-174394 https://reactome.org/PathwayBrowser/#/R-SCE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Saccharomyces cerevisiae 43474 R-SCE-1855154 https://reactome.org/PathwayBrowser/#/R-SCE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-1855165 https://reactome.org/PathwayBrowser/#/R-SCE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-1855166 https://reactome.org/PathwayBrowser/#/R-SCE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-1855174 https://reactome.org/PathwayBrowser/#/R-SCE-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-1855198 https://reactome.org/PathwayBrowser/#/R-SCE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-1855205 https://reactome.org/PathwayBrowser/#/R-SCE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-1855210 https://reactome.org/PathwayBrowser/#/R-SCE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-1855211 https://reactome.org/PathwayBrowser/#/R-SCE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-1855218 https://reactome.org/PathwayBrowser/#/R-SCE-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-191414 https://reactome.org/PathwayBrowser/#/R-SCE-191414 MVD decarboxylates MVA5PP to IPPP IEA Saccharomyces cerevisiae 43474 R-SCE-194153 https://reactome.org/PathwayBrowser/#/R-SCE-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Saccharomyces cerevisiae 43474 R-SCE-197958 https://reactome.org/PathwayBrowser/#/R-SCE-197958 FPGS-2 transforms THF to THFPG IEA Saccharomyces cerevisiae 43474 R-SCE-199456 https://reactome.org/PathwayBrowser/#/R-SCE-199456 PTEN dephosphorylates PIP3 IEA Saccharomyces cerevisiae 43474 R-SCE-199959 https://reactome.org/PathwayBrowser/#/R-SCE-199959 ERKs are inactivated by protein phosphatase 2A IEA Saccharomyces cerevisiae 43474 R-SCE-200555 https://reactome.org/PathwayBrowser/#/R-SCE-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Saccharomyces cerevisiae 43474 R-SCE-200681 https://reactome.org/PathwayBrowser/#/R-SCE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Saccharomyces cerevisiae 43474 R-SCE-200682 https://reactome.org/PathwayBrowser/#/R-SCE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Saccharomyces cerevisiae 43474 R-SCE-200711 https://reactome.org/PathwayBrowser/#/R-SCE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Saccharomyces cerevisiae 43474 R-SCE-2023971 https://reactome.org/PathwayBrowser/#/R-SCE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-2023973 https://reactome.org/PathwayBrowser/#/R-SCE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-2029468 https://reactome.org/PathwayBrowser/#/R-SCE-2029468 Conversion of PA into DAG by PAP-1 IEA Saccharomyces cerevisiae 43474 R-SCE-2046093 https://reactome.org/PathwayBrowser/#/R-SCE-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Saccharomyces cerevisiae 43474 R-SCE-2408551 https://reactome.org/PathwayBrowser/#/R-SCE-2408551 SeMet is converted to AdoSeMet by MAT IEA Saccharomyces cerevisiae 43474 R-SCE-2529015 https://reactome.org/PathwayBrowser/#/R-SCE-2529015 Dephosphorylation of CK2-modified condensin I IEA Saccharomyces cerevisiae 43474 R-SCE-265783 https://reactome.org/PathwayBrowser/#/R-SCE-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Saccharomyces cerevisiae 43474 R-SCE-266082 https://reactome.org/PathwayBrowser/#/R-SCE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Saccharomyces cerevisiae 43474 R-SCE-3095901 https://reactome.org/PathwayBrowser/#/R-SCE-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Saccharomyces cerevisiae 43474 R-SCE-3371422 https://reactome.org/PathwayBrowser/#/R-SCE-3371422 ATP hydrolysis by HSP70 IEA Saccharomyces cerevisiae 43474 R-SCE-372843 https://reactome.org/PathwayBrowser/#/R-SCE-372843 SLC25A10 mediates exchange of malate and phosphate IEA Saccharomyces cerevisiae 43474 R-SCE-3781011 https://reactome.org/PathwayBrowser/#/R-SCE-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Saccharomyces cerevisiae 43474 R-SCE-3781018 https://reactome.org/PathwayBrowser/#/R-SCE-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Saccharomyces cerevisiae 43474 R-SCE-382560 https://reactome.org/PathwayBrowser/#/R-SCE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Saccharomyces cerevisiae 43474 R-SCE-382575 https://reactome.org/PathwayBrowser/#/R-SCE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Saccharomyces cerevisiae 43474 R-SCE-390329 https://reactome.org/PathwayBrowser/#/R-SCE-390329 Dephosphorylation of AKT by PP2A IEA Saccharomyces cerevisiae 43474 R-SCE-427605 https://reactome.org/PathwayBrowser/#/R-SCE-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-428664 https://reactome.org/PathwayBrowser/#/R-SCE-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Saccharomyces cerevisiae 43474 R-SCE-428690 https://reactome.org/PathwayBrowser/#/R-SCE-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Saccharomyces cerevisiae 43474 R-SCE-428696 https://reactome.org/PathwayBrowser/#/R-SCE-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Saccharomyces cerevisiae 43474 R-SCE-449937 https://reactome.org/PathwayBrowser/#/R-SCE-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Saccharomyces cerevisiae 43474 R-SCE-453339 https://reactome.org/PathwayBrowser/#/R-SCE-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Saccharomyces cerevisiae 43474 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 43474 R-SCE-504054 https://reactome.org/PathwayBrowser/#/R-SCE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Saccharomyces cerevisiae 43474 R-SCE-508040 https://reactome.org/PathwayBrowser/#/R-SCE-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Saccharomyces cerevisiae 43474 R-SCE-5221130 https://reactome.org/PathwayBrowser/#/R-SCE-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Saccharomyces cerevisiae 43474 R-SCE-5251955 https://reactome.org/PathwayBrowser/#/R-SCE-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Saccharomyces cerevisiae 43474 R-SCE-5251959 https://reactome.org/PathwayBrowser/#/R-SCE-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-5251989 https://reactome.org/PathwayBrowser/#/R-SCE-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Saccharomyces cerevisiae 43474 R-SCE-5679041 https://reactome.org/PathwayBrowser/#/R-SCE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 43474 R-SCE-5683405 https://reactome.org/PathwayBrowser/#/R-SCE-5683405 PPP5C dephosphorylates TP53BP1 IEA Saccharomyces cerevisiae 43474 R-SCE-5683925 https://reactome.org/PathwayBrowser/#/R-SCE-5683925 ULK1 is dephosphorylated IEA Saccharomyces cerevisiae 43474 R-SCE-5692462 https://reactome.org/PathwayBrowser/#/R-SCE-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Saccharomyces cerevisiae 43474 R-SCE-5692480 https://reactome.org/PathwayBrowser/#/R-SCE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Saccharomyces cerevisiae 43474 R-SCE-5692754 https://reactome.org/PathwayBrowser/#/R-SCE-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Saccharomyces cerevisiae 43474 R-SCE-5694421 https://reactome.org/PathwayBrowser/#/R-SCE-5694421 PP6 dephosphorylates SEC24 IEA Saccharomyces cerevisiae 43474 R-SCE-5694425 https://reactome.org/PathwayBrowser/#/R-SCE-5694425 NSF ATPase activity dissociates cis-SNARE IEA Saccharomyces cerevisiae 43474 R-SCE-5694527 https://reactome.org/PathwayBrowser/#/R-SCE-5694527 Loss of SAR1B GTPase IEA Saccharomyces cerevisiae 43474 R-SCE-5696839 https://reactome.org/PathwayBrowser/#/R-SCE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Saccharomyces cerevisiae 43474 R-SCE-6782131 https://reactome.org/PathwayBrowser/#/R-SCE-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Saccharomyces cerevisiae 43474 R-SCE-6788295 https://reactome.org/PathwayBrowser/#/R-SCE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Saccharomyces cerevisiae 43474 R-SCE-6797630 https://reactome.org/PathwayBrowser/#/R-SCE-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Saccharomyces cerevisiae 43474 R-SCE-6801342 https://reactome.org/PathwayBrowser/#/R-SCE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Saccharomyces cerevisiae 43474 R-SCE-6801456 https://reactome.org/PathwayBrowser/#/R-SCE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Saccharomyces cerevisiae 43474 R-SCE-6806967 https://reactome.org/PathwayBrowser/#/R-SCE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Saccharomyces cerevisiae 43474 R-SCE-6809015 https://reactome.org/PathwayBrowser/#/R-SCE-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Saccharomyces cerevisiae 43474 R-SCE-6809320 https://reactome.org/PathwayBrowser/#/R-SCE-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Saccharomyces cerevisiae 43474 R-SCE-6809325 https://reactome.org/PathwayBrowser/#/R-SCE-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Saccharomyces cerevisiae 43474 R-SCE-6809720 https://reactome.org/PathwayBrowser/#/R-SCE-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Saccharomyces cerevisiae 43474 R-SCE-6809777 https://reactome.org/PathwayBrowser/#/R-SCE-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Saccharomyces cerevisiae 43474 R-SCE-6809778 https://reactome.org/PathwayBrowser/#/R-SCE-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Saccharomyces cerevisiae 43474 R-SCE-6811422 https://reactome.org/PathwayBrowser/#/R-SCE-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Saccharomyces cerevisiae 43474 R-SCE-6811504 https://reactome.org/PathwayBrowser/#/R-SCE-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Saccharomyces cerevisiae 43474 R-SCE-6814120 https://reactome.org/PathwayBrowser/#/R-SCE-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Saccharomyces cerevisiae 43474 R-SCE-68954 https://reactome.org/PathwayBrowser/#/R-SCE-68954 Mcm2-7 is phosphorylated by DDK IEA Saccharomyces cerevisiae 43474 R-SCE-70262 https://reactome.org/PathwayBrowser/#/R-SCE-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Saccharomyces cerevisiae 43474 R-SCE-70449 https://reactome.org/PathwayBrowser/#/R-SCE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Saccharomyces cerevisiae 43474 R-SCE-70479 https://reactome.org/PathwayBrowser/#/R-SCE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Saccharomyces cerevisiae 43474 R-SCE-70482 https://reactome.org/PathwayBrowser/#/R-SCE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Saccharomyces cerevisiae 43474 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 43474 R-SCE-70555 https://reactome.org/PathwayBrowser/#/R-SCE-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Saccharomyces cerevisiae 43474 R-SCE-70560 https://reactome.org/PathwayBrowser/#/R-SCE-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Saccharomyces cerevisiae 43474 R-SCE-70606 https://reactome.org/PathwayBrowser/#/R-SCE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Saccharomyces cerevisiae 43474 R-SCE-70997 https://reactome.org/PathwayBrowser/#/R-SCE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Saccharomyces cerevisiae 43474 R-SCE-71590 https://reactome.org/PathwayBrowser/#/R-SCE-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Saccharomyces cerevisiae 43474 R-SCE-71732 https://reactome.org/PathwayBrowser/#/R-SCE-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Saccharomyces cerevisiae 43474 R-SCE-72621 https://reactome.org/PathwayBrowser/#/R-SCE-72621 Ribosomal scanning IEA Saccharomyces cerevisiae 43474 R-SCE-72647 https://reactome.org/PathwayBrowser/#/R-SCE-72647 Cap-bound mRNA is activated by helicases IEA Saccharomyces cerevisiae 43474 R-SCE-72671 https://reactome.org/PathwayBrowser/#/R-SCE-72671 eIF5B:GTP is hydrolyzed and released IEA Saccharomyces cerevisiae 43474 R-SCE-73573 https://reactome.org/PathwayBrowser/#/R-SCE-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Saccharomyces cerevisiae 43474 R-SCE-73577 https://reactome.org/PathwayBrowser/#/R-SCE-73577 CAD hexamer transforms L-Gln to CAP IEA Saccharomyces cerevisiae 43474 R-SCE-73647 https://reactome.org/PathwayBrowser/#/R-SCE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Saccharomyces cerevisiae 43474 R-SCE-73810 https://reactome.org/PathwayBrowser/#/R-SCE-73810 FGAM + ATP => AIR + ADP + Pi IEA Saccharomyces cerevisiae 43474 R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 43474 R-SCE-73814 https://reactome.org/PathwayBrowser/#/R-SCE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Saccharomyces cerevisiae 43474 R-SCE-74242 https://reactome.org/PathwayBrowser/#/R-SCE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Saccharomyces cerevisiae 43474 R-SCE-74249 https://reactome.org/PathwayBrowser/#/R-SCE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Saccharomyces cerevisiae 43474 R-SCE-75851 https://reactome.org/PathwayBrowser/#/R-SCE-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 43474 R-SCE-75899 https://reactome.org/PathwayBrowser/#/R-SCE-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Saccharomyces cerevisiae 43474 R-SCE-75949 https://reactome.org/PathwayBrowser/#/R-SCE-75949 RNA Polymerase II Promoter Opening: First Transition IEA Saccharomyces cerevisiae 43474 R-SCE-77078 https://reactome.org/PathwayBrowser/#/R-SCE-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Saccharomyces cerevisiae 43474 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 43474 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 43474 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 43474 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 43474 R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 43474 R-SCE-8854255 https://reactome.org/PathwayBrowser/#/R-SCE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 43474 R-SCE-8854329 https://reactome.org/PathwayBrowser/#/R-SCE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 43474 R-SCE-8876889 https://reactome.org/PathwayBrowser/#/R-SCE-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 43474 R-SCE-8952137 https://reactome.org/PathwayBrowser/#/R-SCE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Saccharomyces cerevisiae 43474 R-SCE-8981637 https://reactome.org/PathwayBrowser/#/R-SCE-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Saccharomyces cerevisiae 43474 R-SCE-8982020 https://reactome.org/PathwayBrowser/#/R-SCE-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Saccharomyces cerevisiae 43474 R-SCE-8982021 https://reactome.org/PathwayBrowser/#/R-SCE-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Saccharomyces cerevisiae 43474 R-SCE-8982025 https://reactome.org/PathwayBrowser/#/R-SCE-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Saccharomyces cerevisiae 43474 R-SCE-9013022 https://reactome.org/PathwayBrowser/#/R-SCE-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Saccharomyces cerevisiae 43474 R-SCE-9013111 https://reactome.org/PathwayBrowser/#/R-SCE-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Saccharomyces cerevisiae 43474 R-SCE-9013161 https://reactome.org/PathwayBrowser/#/R-SCE-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Saccharomyces cerevisiae 43474 R-SCE-9013437 https://reactome.org/PathwayBrowser/#/R-SCE-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Saccharomyces cerevisiae 43474 R-SCE-9017488 https://reactome.org/PathwayBrowser/#/R-SCE-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Saccharomyces cerevisiae 43474 R-SCE-9018745 https://reactome.org/PathwayBrowser/#/R-SCE-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Saccharomyces cerevisiae 43474 R-SCE-9018814 https://reactome.org/PathwayBrowser/#/R-SCE-9018814 RHOT1 hydrolyzes GTP IEA Saccharomyces cerevisiae 43474 R-SCE-9018826 https://reactome.org/PathwayBrowser/#/R-SCE-9018826 RHOT2 hydrolyzes GTP IEA Saccharomyces cerevisiae 43474 R-SCE-917693 https://reactome.org/PathwayBrowser/#/R-SCE-917693 ESCRT Disassembly IEA Saccharomyces cerevisiae 43474 R-SCE-917841 https://reactome.org/PathwayBrowser/#/R-SCE-917841 Acidification of Tf:TfR1 containing endosome IEA Saccharomyces cerevisiae 43474 R-SCE-917979 https://reactome.org/PathwayBrowser/#/R-SCE-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Saccharomyces cerevisiae 43474 R-SCE-936883 https://reactome.org/PathwayBrowser/#/R-SCE-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Saccharomyces cerevisiae 43474 R-SCE-936895 https://reactome.org/PathwayBrowser/#/R-SCE-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Saccharomyces cerevisiae 43474 R-SCE-939763 https://reactome.org/PathwayBrowser/#/R-SCE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Saccharomyces cerevisiae 43474 R-SCE-947591 https://reactome.org/PathwayBrowser/#/R-SCE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Saccharomyces cerevisiae 43474 R-SCE-9624893 https://reactome.org/PathwayBrowser/#/R-SCE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Saccharomyces cerevisiae 43474 R-SCE-9629050 https://reactome.org/PathwayBrowser/#/R-SCE-9629050 SBH1:GET3:ATP:GET4:MDY2:SGT2 dissociates and GET3 hydrolyzes ATP yielding SBH1:GET3:ADP TAS Saccharomyces cerevisiae 43474 R-SCE-9635739 https://reactome.org/PathwayBrowser/#/R-SCE-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Saccharomyces cerevisiae 43474 R-SCE-9640195 https://reactome.org/PathwayBrowser/#/R-SCE-9640195 RRAGA,B hydrolyzes GTP IEA Saccharomyces cerevisiae 43474 R-SCE-9645598 https://reactome.org/PathwayBrowser/#/R-SCE-9645598 RRAGC,D hydrolyzes GTP IEA Saccharomyces cerevisiae 43474 R-SCE-9661417 https://reactome.org/PathwayBrowser/#/R-SCE-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 43474 R-SCE-9684118 https://reactome.org/PathwayBrowser/#/R-SCE-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Saccharomyces cerevisiae 43474 R-SCE-9693282 https://reactome.org/PathwayBrowser/#/R-SCE-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Saccharomyces cerevisiae 43474 R-SCE-9750656 https://reactome.org/PathwayBrowser/#/R-SCE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Saccharomyces cerevisiae 43474 R-SCE-9753278 https://reactome.org/PathwayBrowser/#/R-SCE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 43474 R-SCE-9753283 https://reactome.org/PathwayBrowser/#/R-SCE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 43474 R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 43474 R-SCE-977324 https://reactome.org/PathwayBrowser/#/R-SCE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Saccharomyces cerevisiae 43474 R-SCE-9837419 https://reactome.org/PathwayBrowser/#/R-SCE-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Saccharomyces cerevisiae 43474 R-SCE-9838004 https://reactome.org/PathwayBrowser/#/R-SCE-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 43474 R-SCE-9838081 https://reactome.org/PathwayBrowser/#/R-SCE-9838081 LONP1 degrades mitochondrial matrix proteins IEA Saccharomyces cerevisiae 43474 R-SCE-9839105 https://reactome.org/PathwayBrowser/#/R-SCE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Saccharomyces cerevisiae 43474 R-SCE-9839113 https://reactome.org/PathwayBrowser/#/R-SCE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 43474 R-SCE-9839836 https://reactome.org/PathwayBrowser/#/R-SCE-9839836 YME1 degrades TIM10 TAS Saccharomyces cerevisiae 43474 R-SCE-9843721 https://reactome.org/PathwayBrowser/#/R-SCE-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Saccharomyces cerevisiae 43474 R-SCE-9853385 https://reactome.org/PathwayBrowser/#/R-SCE-9853385 PPP1CC dephosphorylates PLK1 IEA Saccharomyces cerevisiae 43474 R-SPO-111215 https://reactome.org/PathwayBrowser/#/R-SPO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Schizosaccharomyces pombe 43474 R-SPO-111524 https://reactome.org/PathwayBrowser/#/R-SPO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Schizosaccharomyces pombe 43474 R-SPO-112033 https://reactome.org/PathwayBrowser/#/R-SPO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Schizosaccharomyces pombe 43474 R-SPO-112034 https://reactome.org/PathwayBrowser/#/R-SPO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Schizosaccharomyces pombe 43474 R-SPO-112037 https://reactome.org/PathwayBrowser/#/R-SPO-112037 Inactivation of PLC beta IEA Schizosaccharomyces pombe 43474 R-SPO-1237129 https://reactome.org/PathwayBrowser/#/R-SPO-1237129 Acireductone is created IEA Schizosaccharomyces pombe 43474 R-SPO-1237160 https://reactome.org/PathwayBrowser/#/R-SPO-1237160 MTA is cleaved and phosphorylated IEA Schizosaccharomyces pombe 43474 R-SPO-1247935 https://reactome.org/PathwayBrowser/#/R-SPO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Schizosaccharomyces pombe 43474 R-SPO-1369065 https://reactome.org/PathwayBrowser/#/R-SPO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Schizosaccharomyces pombe 43474 R-SPO-1454916 https://reactome.org/PathwayBrowser/#/R-SPO-1454916 The ABCC family mediates organic anion transport IEA Schizosaccharomyces pombe 43474 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 43474 R-SPO-1483203 https://reactome.org/PathwayBrowser/#/R-SPO-1483203 PA is dephosphorylated to DAG by LPIN IEA Schizosaccharomyces pombe 43474 R-SPO-1675795 https://reactome.org/PathwayBrowser/#/R-SPO-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1675824 https://reactome.org/PathwayBrowser/#/R-SPO-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1675836 https://reactome.org/PathwayBrowser/#/R-SPO-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1675988 https://reactome.org/PathwayBrowser/#/R-SPO-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1675994 https://reactome.org/PathwayBrowser/#/R-SPO-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1676065 https://reactome.org/PathwayBrowser/#/R-SPO-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1676105 https://reactome.org/PathwayBrowser/#/R-SPO-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1676114 https://reactome.org/PathwayBrowser/#/R-SPO-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1676124 https://reactome.org/PathwayBrowser/#/R-SPO-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1676133 https://reactome.org/PathwayBrowser/#/R-SPO-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1676141 https://reactome.org/PathwayBrowser/#/R-SPO-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1676149 https://reactome.org/PathwayBrowser/#/R-SPO-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1676177 https://reactome.org/PathwayBrowser/#/R-SPO-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1676203 https://reactome.org/PathwayBrowser/#/R-SPO-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1676204 https://reactome.org/PathwayBrowser/#/R-SPO-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Schizosaccharomyces pombe 43474 R-SPO-174110 https://reactome.org/PathwayBrowser/#/R-SPO-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Schizosaccharomyces pombe 43474 R-SPO-174367 https://reactome.org/PathwayBrowser/#/R-SPO-174367 GCL ligates L-Glu to L-Cys IEA Schizosaccharomyces pombe 43474 R-SPO-174391 https://reactome.org/PathwayBrowser/#/R-SPO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Schizosaccharomyces pombe 43474 R-SPO-174394 https://reactome.org/PathwayBrowser/#/R-SPO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Schizosaccharomyces pombe 43474 R-SPO-1855165 https://reactome.org/PathwayBrowser/#/R-SPO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 43474 R-SPO-1855166 https://reactome.org/PathwayBrowser/#/R-SPO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Schizosaccharomyces pombe 43474 R-SPO-1855174 https://reactome.org/PathwayBrowser/#/R-SPO-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Schizosaccharomyces pombe 43474 R-SPO-1855198 https://reactome.org/PathwayBrowser/#/R-SPO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 43474 R-SPO-1855205 https://reactome.org/PathwayBrowser/#/R-SPO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Schizosaccharomyces pombe 43474 R-SPO-1855213 https://reactome.org/PathwayBrowser/#/R-SPO-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-1855218 https://reactome.org/PathwayBrowser/#/R-SPO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Schizosaccharomyces pombe 43474 R-SPO-1855222 https://reactome.org/PathwayBrowser/#/R-SPO-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-191414 https://reactome.org/PathwayBrowser/#/R-SPO-191414 MVD decarboxylates MVA5PP to IPPP IEA Schizosaccharomyces pombe 43474 R-SPO-193362 https://reactome.org/PathwayBrowser/#/R-SPO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 43474 R-SPO-194153 https://reactome.org/PathwayBrowser/#/R-SPO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 43474 R-SPO-197958 https://reactome.org/PathwayBrowser/#/R-SPO-197958 FPGS-2 transforms THF to THFPG IEA Schizosaccharomyces pombe 43474 R-SPO-199456 https://reactome.org/PathwayBrowser/#/R-SPO-199456 PTEN dephosphorylates PIP3 IEA Schizosaccharomyces pombe 43474 R-SPO-199959 https://reactome.org/PathwayBrowser/#/R-SPO-199959 ERKs are inactivated by protein phosphatase 2A IEA Schizosaccharomyces pombe 43474 R-SPO-200555 https://reactome.org/PathwayBrowser/#/R-SPO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Schizosaccharomyces pombe 43474 R-SPO-200681 https://reactome.org/PathwayBrowser/#/R-SPO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Schizosaccharomyces pombe 43474 R-SPO-200682 https://reactome.org/PathwayBrowser/#/R-SPO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Schizosaccharomyces pombe 43474 R-SPO-200711 https://reactome.org/PathwayBrowser/#/R-SPO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Schizosaccharomyces pombe 43474 R-SPO-2023971 https://reactome.org/PathwayBrowser/#/R-SPO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 43474 R-SPO-2023973 https://reactome.org/PathwayBrowser/#/R-SPO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 43474 R-SPO-2029468 https://reactome.org/PathwayBrowser/#/R-SPO-2029468 Conversion of PA into DAG by PAP-1 IEA Schizosaccharomyces pombe 43474 R-SPO-2408551 https://reactome.org/PathwayBrowser/#/R-SPO-2408551 SeMet is converted to AdoSeMet by MAT IEA Schizosaccharomyces pombe 43474 R-SPO-2529015 https://reactome.org/PathwayBrowser/#/R-SPO-2529015 Dephosphorylation of CK2-modified condensin I IEA Schizosaccharomyces pombe 43474 R-SPO-3095901 https://reactome.org/PathwayBrowser/#/R-SPO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Schizosaccharomyces pombe 43474 R-SPO-3371422 https://reactome.org/PathwayBrowser/#/R-SPO-3371422 ATP hydrolysis by HSP70 IEA Schizosaccharomyces pombe 43474 R-SPO-382560 https://reactome.org/PathwayBrowser/#/R-SPO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Schizosaccharomyces pombe 43474 R-SPO-390329 https://reactome.org/PathwayBrowser/#/R-SPO-390329 Dephosphorylation of AKT by PP2A IEA Schizosaccharomyces pombe 43474 R-SPO-428664 https://reactome.org/PathwayBrowser/#/R-SPO-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Schizosaccharomyces pombe 43474 R-SPO-428690 https://reactome.org/PathwayBrowser/#/R-SPO-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Schizosaccharomyces pombe 43474 R-SPO-428696 https://reactome.org/PathwayBrowser/#/R-SPO-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Schizosaccharomyces pombe 43474 R-SPO-4419948 https://reactome.org/PathwayBrowser/#/R-SPO-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Schizosaccharomyces pombe 43474 R-SPO-446200 https://reactome.org/PathwayBrowser/#/R-SPO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Schizosaccharomyces pombe 43474 R-SPO-449937 https://reactome.org/PathwayBrowser/#/R-SPO-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Schizosaccharomyces pombe 43474 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 43474 R-SPO-504054 https://reactome.org/PathwayBrowser/#/R-SPO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Schizosaccharomyces pombe 43474 R-SPO-508040 https://reactome.org/PathwayBrowser/#/R-SPO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Schizosaccharomyces pombe 43474 R-SPO-5221130 https://reactome.org/PathwayBrowser/#/R-SPO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Schizosaccharomyces pombe 43474 R-SPO-5223317 https://reactome.org/PathwayBrowser/#/R-SPO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 43474 R-SPO-5251955 https://reactome.org/PathwayBrowser/#/R-SPO-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Schizosaccharomyces pombe 43474 R-SPO-5251959 https://reactome.org/PathwayBrowser/#/R-SPO-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Schizosaccharomyces pombe 43474 R-SPO-5251989 https://reactome.org/PathwayBrowser/#/R-SPO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Schizosaccharomyces pombe 43474 R-SPO-5678706 https://reactome.org/PathwayBrowser/#/R-SPO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Schizosaccharomyces pombe 43474 R-SPO-5679041 https://reactome.org/PathwayBrowser/#/R-SPO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Schizosaccharomyces pombe 43474 R-SPO-5683405 https://reactome.org/PathwayBrowser/#/R-SPO-5683405 PPP5C dephosphorylates TP53BP1 IEA Schizosaccharomyces pombe 43474 R-SPO-5683925 https://reactome.org/PathwayBrowser/#/R-SPO-5683925 ULK1 is dephosphorylated IEA Schizosaccharomyces pombe 43474 R-SPO-5690996 https://reactome.org/PathwayBrowser/#/R-SPO-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Schizosaccharomyces pombe 43474 R-SPO-5692462 https://reactome.org/PathwayBrowser/#/R-SPO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Schizosaccharomyces pombe 43474 R-SPO-5692480 https://reactome.org/PathwayBrowser/#/R-SPO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 43474 R-SPO-5692754 https://reactome.org/PathwayBrowser/#/R-SPO-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Schizosaccharomyces pombe 43474 R-SPO-5694425 https://reactome.org/PathwayBrowser/#/R-SPO-5694425 NSF ATPase activity dissociates cis-SNARE IEA Schizosaccharomyces pombe 43474 R-SPO-5694527 https://reactome.org/PathwayBrowser/#/R-SPO-5694527 Loss of SAR1B GTPase IEA Schizosaccharomyces pombe 43474 R-SPO-5696839 https://reactome.org/PathwayBrowser/#/R-SPO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Schizosaccharomyces pombe 43474 R-SPO-6782131 https://reactome.org/PathwayBrowser/#/R-SPO-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Schizosaccharomyces pombe 43474 R-SPO-6788295 https://reactome.org/PathwayBrowser/#/R-SPO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Schizosaccharomyces pombe 43474 R-SPO-6797630 https://reactome.org/PathwayBrowser/#/R-SPO-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Schizosaccharomyces pombe 43474 R-SPO-6801342 https://reactome.org/PathwayBrowser/#/R-SPO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Schizosaccharomyces pombe 43474 R-SPO-6801456 https://reactome.org/PathwayBrowser/#/R-SPO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Schizosaccharomyces pombe 43474 R-SPO-6806967 https://reactome.org/PathwayBrowser/#/R-SPO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Schizosaccharomyces pombe 43474 R-SPO-6809015 https://reactome.org/PathwayBrowser/#/R-SPO-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Schizosaccharomyces pombe 43474 R-SPO-6809320 https://reactome.org/PathwayBrowser/#/R-SPO-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-6809325 https://reactome.org/PathwayBrowser/#/R-SPO-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-6809720 https://reactome.org/PathwayBrowser/#/R-SPO-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Schizosaccharomyces pombe 43474 R-SPO-6809777 https://reactome.org/PathwayBrowser/#/R-SPO-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Schizosaccharomyces pombe 43474 R-SPO-6809778 https://reactome.org/PathwayBrowser/#/R-SPO-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Schizosaccharomyces pombe 43474 R-SPO-6811422 https://reactome.org/PathwayBrowser/#/R-SPO-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Schizosaccharomyces pombe 43474 R-SPO-6811504 https://reactome.org/PathwayBrowser/#/R-SPO-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Schizosaccharomyces pombe 43474 R-SPO-6814120 https://reactome.org/PathwayBrowser/#/R-SPO-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Schizosaccharomyces pombe 43474 R-SPO-68954 https://reactome.org/PathwayBrowser/#/R-SPO-68954 Mcm2-7 is phosphorylated by DDK IEA Schizosaccharomyces pombe 43474 R-SPO-70262 https://reactome.org/PathwayBrowser/#/R-SPO-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Schizosaccharomyces pombe 43474 R-SPO-70449 https://reactome.org/PathwayBrowser/#/R-SPO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Schizosaccharomyces pombe 43474 R-SPO-70479 https://reactome.org/PathwayBrowser/#/R-SPO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Schizosaccharomyces pombe 43474 R-SPO-70482 https://reactome.org/PathwayBrowser/#/R-SPO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Schizosaccharomyces pombe 43474 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 43474 R-SPO-70555 https://reactome.org/PathwayBrowser/#/R-SPO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Schizosaccharomyces pombe 43474 R-SPO-70560 https://reactome.org/PathwayBrowser/#/R-SPO-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Schizosaccharomyces pombe 43474 R-SPO-70606 https://reactome.org/PathwayBrowser/#/R-SPO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Schizosaccharomyces pombe 43474 R-SPO-70997 https://reactome.org/PathwayBrowser/#/R-SPO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Schizosaccharomyces pombe 43474 R-SPO-71732 https://reactome.org/PathwayBrowser/#/R-SPO-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Schizosaccharomyces pombe 43474 R-SPO-72619 https://reactome.org/PathwayBrowser/#/R-SPO-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Schizosaccharomyces pombe 43474 R-SPO-72621 https://reactome.org/PathwayBrowser/#/R-SPO-72621 Ribosomal scanning IEA Schizosaccharomyces pombe 43474 R-SPO-72647 https://reactome.org/PathwayBrowser/#/R-SPO-72647 Cap-bound mRNA is activated by helicases IEA Schizosaccharomyces pombe 43474 R-SPO-72671 https://reactome.org/PathwayBrowser/#/R-SPO-72671 eIF5B:GTP is hydrolyzed and released IEA Schizosaccharomyces pombe 43474 R-SPO-73573 https://reactome.org/PathwayBrowser/#/R-SPO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Schizosaccharomyces pombe 43474 R-SPO-73577 https://reactome.org/PathwayBrowser/#/R-SPO-73577 CAD hexamer transforms L-Gln to CAP IEA Schizosaccharomyces pombe 43474 R-SPO-73647 https://reactome.org/PathwayBrowser/#/R-SPO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Schizosaccharomyces pombe 43474 R-SPO-73810 https://reactome.org/PathwayBrowser/#/R-SPO-73810 FGAM + ATP => AIR + ADP + Pi IEA Schizosaccharomyces pombe 43474 R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 43474 R-SPO-73814 https://reactome.org/PathwayBrowser/#/R-SPO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Schizosaccharomyces pombe 43474 R-SPO-74242 https://reactome.org/PathwayBrowser/#/R-SPO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Schizosaccharomyces pombe 43474 R-SPO-74249 https://reactome.org/PathwayBrowser/#/R-SPO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Schizosaccharomyces pombe 43474 R-SPO-75848 https://reactome.org/PathwayBrowser/#/R-SPO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Schizosaccharomyces pombe 43474 R-SPO-75851 https://reactome.org/PathwayBrowser/#/R-SPO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 43474 R-SPO-75899 https://reactome.org/PathwayBrowser/#/R-SPO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Schizosaccharomyces pombe 43474 R-SPO-75949 https://reactome.org/PathwayBrowser/#/R-SPO-75949 RNA Polymerase II Promoter Opening: First Transition IEA Schizosaccharomyces pombe 43474 R-SPO-77078 https://reactome.org/PathwayBrowser/#/R-SPO-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Schizosaccharomyces pombe 43474 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 43474 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 43474 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 43474 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 43474 R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 43474 R-SPO-8854255 https://reactome.org/PathwayBrowser/#/R-SPO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 43474 R-SPO-8854329 https://reactome.org/PathwayBrowser/#/R-SPO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 43474 R-SPO-8876889 https://reactome.org/PathwayBrowser/#/R-SPO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 43474 R-SPO-8878654 https://reactome.org/PathwayBrowser/#/R-SPO-8878654 ACP6 hydrolyses MYS-LPA IEA Schizosaccharomyces pombe 43474 R-SPO-8981637 https://reactome.org/PathwayBrowser/#/R-SPO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Schizosaccharomyces pombe 43474 R-SPO-8982020 https://reactome.org/PathwayBrowser/#/R-SPO-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Schizosaccharomyces pombe 43474 R-SPO-8982021 https://reactome.org/PathwayBrowser/#/R-SPO-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Schizosaccharomyces pombe 43474 R-SPO-8982025 https://reactome.org/PathwayBrowser/#/R-SPO-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Schizosaccharomyces pombe 43474 R-SPO-9013022 https://reactome.org/PathwayBrowser/#/R-SPO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Schizosaccharomyces pombe 43474 R-SPO-9013111 https://reactome.org/PathwayBrowser/#/R-SPO-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Schizosaccharomyces pombe 43474 R-SPO-9013161 https://reactome.org/PathwayBrowser/#/R-SPO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Schizosaccharomyces pombe 43474 R-SPO-9013437 https://reactome.org/PathwayBrowser/#/R-SPO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Schizosaccharomyces pombe 43474 R-SPO-9017488 https://reactome.org/PathwayBrowser/#/R-SPO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Schizosaccharomyces pombe 43474 R-SPO-9018745 https://reactome.org/PathwayBrowser/#/R-SPO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Schizosaccharomyces pombe 43474 R-SPO-9018814 https://reactome.org/PathwayBrowser/#/R-SPO-9018814 RHOT1 hydrolyzes GTP IEA Schizosaccharomyces pombe 43474 R-SPO-9018826 https://reactome.org/PathwayBrowser/#/R-SPO-9018826 RHOT2 hydrolyzes GTP IEA Schizosaccharomyces pombe 43474 R-SPO-917693 https://reactome.org/PathwayBrowser/#/R-SPO-917693 ESCRT Disassembly IEA Schizosaccharomyces pombe 43474 R-SPO-917841 https://reactome.org/PathwayBrowser/#/R-SPO-917841 Acidification of Tf:TfR1 containing endosome IEA Schizosaccharomyces pombe 43474 R-SPO-936883 https://reactome.org/PathwayBrowser/#/R-SPO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Schizosaccharomyces pombe 43474 R-SPO-936895 https://reactome.org/PathwayBrowser/#/R-SPO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Schizosaccharomyces pombe 43474 R-SPO-939763 https://reactome.org/PathwayBrowser/#/R-SPO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-947591 https://reactome.org/PathwayBrowser/#/R-SPO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Schizosaccharomyces pombe 43474 R-SPO-9624893 https://reactome.org/PathwayBrowser/#/R-SPO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Schizosaccharomyces pombe 43474 R-SPO-9635739 https://reactome.org/PathwayBrowser/#/R-SPO-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Schizosaccharomyces pombe 43474 R-SPO-9640195 https://reactome.org/PathwayBrowser/#/R-SPO-9640195 RRAGA,B hydrolyzes GTP IEA Schizosaccharomyces pombe 43474 R-SPO-9645598 https://reactome.org/PathwayBrowser/#/R-SPO-9645598 RRAGC,D hydrolyzes GTP IEA Schizosaccharomyces pombe 43474 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 43474 R-SPO-9684118 https://reactome.org/PathwayBrowser/#/R-SPO-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Schizosaccharomyces pombe 43474 R-SPO-9693282 https://reactome.org/PathwayBrowser/#/R-SPO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Schizosaccharomyces pombe 43474 R-SPO-9750656 https://reactome.org/PathwayBrowser/#/R-SPO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Schizosaccharomyces pombe 43474 R-SPO-9753278 https://reactome.org/PathwayBrowser/#/R-SPO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 43474 R-SPO-9753283 https://reactome.org/PathwayBrowser/#/R-SPO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 43474 R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 43474 R-SPO-9759454 https://reactome.org/PathwayBrowser/#/R-SPO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Schizosaccharomyces pombe 43474 R-SPO-9759461 https://reactome.org/PathwayBrowser/#/R-SPO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Schizosaccharomyces pombe 43474 R-SPO-977324 https://reactome.org/PathwayBrowser/#/R-SPO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Schizosaccharomyces pombe 43474 R-SPO-983144 https://reactome.org/PathwayBrowser/#/R-SPO-983144 Transport of Antigen peptide in to ER IEA Schizosaccharomyces pombe 43474 R-SPO-9837419 https://reactome.org/PathwayBrowser/#/R-SPO-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Schizosaccharomyces pombe 43474 R-SPO-9838004 https://reactome.org/PathwayBrowser/#/R-SPO-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 43474 R-SPO-9838081 https://reactome.org/PathwayBrowser/#/R-SPO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Schizosaccharomyces pombe 43474 R-SPO-9839105 https://reactome.org/PathwayBrowser/#/R-SPO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Schizosaccharomyces pombe 43474 R-SPO-9839113 https://reactome.org/PathwayBrowser/#/R-SPO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 43474 R-SPO-9843721 https://reactome.org/PathwayBrowser/#/R-SPO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Schizosaccharomyces pombe 43474 R-SPO-9853385 https://reactome.org/PathwayBrowser/#/R-SPO-9853385 PPP1CC dephosphorylates PLK1 IEA Schizosaccharomyces pombe 43474 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 43474 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 43474 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 43474 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 43474 R-SSC-109415 https://reactome.org/PathwayBrowser/#/R-SSC-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Sus scrofa 43474 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 43474 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 43474 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 43474 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 43474 R-SSC-111215 https://reactome.org/PathwayBrowser/#/R-SSC-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Sus scrofa 43474 R-SSC-111524 https://reactome.org/PathwayBrowser/#/R-SSC-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Sus scrofa 43474 R-SSC-112033 https://reactome.org/PathwayBrowser/#/R-SSC-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Sus scrofa 43474 R-SSC-112034 https://reactome.org/PathwayBrowser/#/R-SSC-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Sus scrofa 43474 R-SSC-112037 https://reactome.org/PathwayBrowser/#/R-SSC-112037 Inactivation of PLC beta IEA Sus scrofa 43474 R-SSC-113503 https://reactome.org/PathwayBrowser/#/R-SSC-113503 PP2A mediated localization of RB1 protein in chromatin IEA Sus scrofa 43474 R-SSC-1169192 https://reactome.org/PathwayBrowser/#/R-SSC-1169192 PTP1B dephosphorylates GHR IEA Sus scrofa 43474 R-SSC-1237129 https://reactome.org/PathwayBrowser/#/R-SSC-1237129 Acireductone is created IEA Sus scrofa 43474 R-SSC-1237160 https://reactome.org/PathwayBrowser/#/R-SSC-1237160 MTA is cleaved and phosphorylated IEA Sus scrofa 43474 R-SSC-1247935 https://reactome.org/PathwayBrowser/#/R-SSC-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Sus scrofa 43474 R-SSC-1295632 https://reactome.org/PathwayBrowser/#/R-SSC-1295632 PPA2A dephosphorylates SPRY2 IEA Sus scrofa 43474 R-SSC-1363274 https://reactome.org/PathwayBrowser/#/R-SSC-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Sus scrofa 43474 R-SSC-1363276 https://reactome.org/PathwayBrowser/#/R-SSC-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Sus scrofa 43474 R-SSC-1369028 https://reactome.org/PathwayBrowser/#/R-SSC-1369028 ABCAs mediate lipid efflux IEA Sus scrofa 43474 R-SSC-1369052 https://reactome.org/PathwayBrowser/#/R-SSC-1369052 ABCAs mediate lipid influx IEA Sus scrofa 43474 R-SSC-1369065 https://reactome.org/PathwayBrowser/#/R-SSC-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Sus scrofa 43474 R-SSC-139906 https://reactome.org/PathwayBrowser/#/R-SSC-139906 Activation of BAD by calcineurin IEA Sus scrofa 43474 R-SSC-1454916 https://reactome.org/PathwayBrowser/#/R-SSC-1454916 The ABCC family mediates organic anion transport IEA Sus scrofa 43474 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-1467466 https://reactome.org/PathwayBrowser/#/R-SSC-1467466 ABCA4 mediates atRAL transport IEA Sus scrofa 43474 R-SSC-1483096 https://reactome.org/PathwayBrowser/#/R-SSC-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Sus scrofa 43474 R-SSC-1483159 https://reactome.org/PathwayBrowser/#/R-SSC-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Sus scrofa 43474 R-SSC-1483203 https://reactome.org/PathwayBrowser/#/R-SSC-1483203 PA is dephosphorylated to DAG by LPIN IEA Sus scrofa 43474 R-SSC-159101 https://reactome.org/PathwayBrowser/#/R-SSC-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Sus scrofa 43474 R-SSC-163120 https://reactome.org/PathwayBrowser/#/R-SSC-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Sus scrofa 43474 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa 43474 R-SSC-164832 https://reactome.org/PathwayBrowser/#/R-SSC-164832 ATPase synthesizes ATP IEA Sus scrofa 43474 R-SSC-164840 https://reactome.org/PathwayBrowser/#/R-SSC-164840 ADP and Pi bind to ATPase IEA Sus scrofa 43474 R-SSC-1675795 https://reactome.org/PathwayBrowser/#/R-SSC-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Sus scrofa 43474 R-SSC-1675824 https://reactome.org/PathwayBrowser/#/R-SSC-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Sus scrofa 43474 R-SSC-1675836 https://reactome.org/PathwayBrowser/#/R-SSC-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Sus scrofa 43474 R-SSC-1675949 https://reactome.org/PathwayBrowser/#/R-SSC-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Sus scrofa 43474 R-SSC-1675988 https://reactome.org/PathwayBrowser/#/R-SSC-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Sus scrofa 43474 R-SSC-1675994 https://reactome.org/PathwayBrowser/#/R-SSC-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Sus scrofa 43474 R-SSC-1676005 https://reactome.org/PathwayBrowser/#/R-SSC-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Sus scrofa 43474 R-SSC-1676020 https://reactome.org/PathwayBrowser/#/R-SSC-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Sus scrofa 43474 R-SSC-1676065 https://reactome.org/PathwayBrowser/#/R-SSC-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Sus scrofa 43474 R-SSC-1676105 https://reactome.org/PathwayBrowser/#/R-SSC-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Sus scrofa 43474 R-SSC-1676114 https://reactome.org/PathwayBrowser/#/R-SSC-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Sus scrofa 43474 R-SSC-1676124 https://reactome.org/PathwayBrowser/#/R-SSC-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Sus scrofa 43474 R-SSC-1676133 https://reactome.org/PathwayBrowser/#/R-SSC-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Sus scrofa 43474 R-SSC-1676141 https://reactome.org/PathwayBrowser/#/R-SSC-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Sus scrofa 43474 R-SSC-1676149 https://reactome.org/PathwayBrowser/#/R-SSC-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Sus scrofa 43474 R-SSC-1676162 https://reactome.org/PathwayBrowser/#/R-SSC-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Sus scrofa 43474 R-SSC-1676164 https://reactome.org/PathwayBrowser/#/R-SSC-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Sus scrofa 43474 R-SSC-1676174 https://reactome.org/PathwayBrowser/#/R-SSC-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Sus scrofa 43474 R-SSC-1676177 https://reactome.org/PathwayBrowser/#/R-SSC-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Sus scrofa 43474 R-SSC-1676203 https://reactome.org/PathwayBrowser/#/R-SSC-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Sus scrofa 43474 R-SSC-1676204 https://reactome.org/PathwayBrowser/#/R-SSC-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Sus scrofa 43474 R-SSC-170153 https://reactome.org/PathwayBrowser/#/R-SSC-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Sus scrofa 43474 R-SSC-170158 https://reactome.org/PathwayBrowser/#/R-SSC-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Sus scrofa 43474 R-SSC-170161 https://reactome.org/PathwayBrowser/#/R-SSC-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Sus scrofa 43474 R-SSC-170666 https://reactome.org/PathwayBrowser/#/R-SSC-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa 43474 R-SSC-170685 https://reactome.org/PathwayBrowser/#/R-SSC-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa 43474 R-SSC-170686 https://reactome.org/PathwayBrowser/#/R-SSC-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Sus scrofa 43474 R-SSC-174110 https://reactome.org/PathwayBrowser/#/R-SSC-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Sus scrofa 43474 R-SSC-174367 https://reactome.org/PathwayBrowser/#/R-SSC-174367 GCL ligates L-Glu to L-Cys IEA Sus scrofa 43474 R-SSC-174391 https://reactome.org/PathwayBrowser/#/R-SSC-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Sus scrofa 43474 R-SSC-174394 https://reactome.org/PathwayBrowser/#/R-SSC-174394 GSS:Mg2+ dimer synthesizes GSH IEA Sus scrofa 43474 R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa 43474 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa 43474 R-SSC-176606 https://reactome.org/PathwayBrowser/#/R-SSC-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Sus scrofa 43474 R-SSC-177923 https://reactome.org/PathwayBrowser/#/R-SSC-177923 Sustained activation of SRC kinase by SHP2 IEA Sus scrofa 43474 R-SSC-177924 https://reactome.org/PathwayBrowser/#/R-SSC-177924 Dephosphorylation of Gab1 by SHP2 IEA Sus scrofa 43474 R-SSC-177926 https://reactome.org/PathwayBrowser/#/R-SSC-177926 Dephosphorylation of PAG by SHP2 IEA Sus scrofa 43474 R-SSC-177935 https://reactome.org/PathwayBrowser/#/R-SSC-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Sus scrofa 43474 R-SSC-1855154 https://reactome.org/PathwayBrowser/#/R-SSC-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 43474 R-SSC-1855159 https://reactome.org/PathwayBrowser/#/R-SSC-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Sus scrofa 43474 R-SSC-1855163 https://reactome.org/PathwayBrowser/#/R-SSC-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Sus scrofa 43474 R-SSC-1855165 https://reactome.org/PathwayBrowser/#/R-SSC-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 43474 R-SSC-1855166 https://reactome.org/PathwayBrowser/#/R-SSC-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Sus scrofa 43474 R-SSC-1855171 https://reactome.org/PathwayBrowser/#/R-SSC-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Sus scrofa 43474 R-SSC-1855174 https://reactome.org/PathwayBrowser/#/R-SSC-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Sus scrofa 43474 R-SSC-1855180 https://reactome.org/PathwayBrowser/#/R-SSC-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Sus scrofa 43474 R-SSC-1855198 https://reactome.org/PathwayBrowser/#/R-SSC-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 43474 R-SSC-1855200 https://reactome.org/PathwayBrowser/#/R-SSC-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Sus scrofa 43474 R-SSC-1855202 https://reactome.org/PathwayBrowser/#/R-SSC-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Sus scrofa 43474 R-SSC-1855205 https://reactome.org/PathwayBrowser/#/R-SSC-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Sus scrofa 43474 R-SSC-1855208 https://reactome.org/PathwayBrowser/#/R-SSC-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Sus scrofa 43474 R-SSC-1855210 https://reactome.org/PathwayBrowser/#/R-SSC-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 43474 R-SSC-1855211 https://reactome.org/PathwayBrowser/#/R-SSC-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 43474 R-SSC-1855213 https://reactome.org/PathwayBrowser/#/R-SSC-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Sus scrofa 43474 R-SSC-1855218 https://reactome.org/PathwayBrowser/#/R-SSC-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Sus scrofa 43474 R-SSC-1855219 https://reactome.org/PathwayBrowser/#/R-SSC-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 43474 R-SSC-1855222 https://reactome.org/PathwayBrowser/#/R-SSC-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Sus scrofa 43474 R-SSC-1855225 https://reactome.org/PathwayBrowser/#/R-SSC-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Sus scrofa 43474 R-SSC-1855232 https://reactome.org/PathwayBrowser/#/R-SSC-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Sus scrofa 43474 R-SSC-1861595 https://reactome.org/PathwayBrowser/#/R-SSC-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Sus scrofa 43474 R-SSC-191414 https://reactome.org/PathwayBrowser/#/R-SSC-191414 MVD decarboxylates MVA5PP to IPPP IEA Sus scrofa 43474 R-SSC-193362 https://reactome.org/PathwayBrowser/#/R-SSC-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-194153 https://reactome.org/PathwayBrowser/#/R-SSC-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-196950 https://reactome.org/PathwayBrowser/#/R-SSC-196950 2xTRAP hydrolyzes FMN to RIB IEA Sus scrofa 43474 R-SSC-197958 https://reactome.org/PathwayBrowser/#/R-SSC-197958 FPGS-2 transforms THF to THFPG IEA Sus scrofa 43474 R-SSC-198513 https://reactome.org/PathwayBrowser/#/R-SSC-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Sus scrofa 43474 R-SSC-199456 https://reactome.org/PathwayBrowser/#/R-SSC-199456 PTEN dephosphorylates PIP3 IEA Sus scrofa 43474 R-SSC-199959 https://reactome.org/PathwayBrowser/#/R-SSC-199959 ERKs are inactivated by protein phosphatase 2A IEA Sus scrofa 43474 R-SSC-200555 https://reactome.org/PathwayBrowser/#/R-SSC-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Sus scrofa 43474 R-SSC-200681 https://reactome.org/PathwayBrowser/#/R-SSC-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Sus scrofa 43474 R-SSC-200682 https://reactome.org/PathwayBrowser/#/R-SSC-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Sus scrofa 43474 R-SSC-200711 https://reactome.org/PathwayBrowser/#/R-SSC-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Sus scrofa 43474 R-SSC-201790 https://reactome.org/PathwayBrowser/#/R-SSC-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Sus scrofa 43474 R-SSC-202214 https://reactome.org/PathwayBrowser/#/R-SSC-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Sus scrofa 43474 R-SSC-202237 https://reactome.org/PathwayBrowser/#/R-SSC-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Sus scrofa 43474 R-SSC-2023971 https://reactome.org/PathwayBrowser/#/R-SSC-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 43474 R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 43474 R-SSC-2029468 https://reactome.org/PathwayBrowser/#/R-SSC-2029468 Conversion of PA into DAG by PAP-1 IEA Sus scrofa 43474 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa 43474 R-SSC-203797 https://reactome.org/PathwayBrowser/#/R-SSC-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Sus scrofa 43474 R-SSC-203973 https://reactome.org/PathwayBrowser/#/R-SSC-203973 Vesicle budding IEA Sus scrofa 43474 R-SSC-204169 https://reactome.org/PathwayBrowser/#/R-SSC-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Sus scrofa 43474 R-SSC-2046093 https://reactome.org/PathwayBrowser/#/R-SSC-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Sus scrofa 43474 R-SSC-209055 https://reactome.org/PathwayBrowser/#/R-SSC-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Sus scrofa 43474 R-SSC-2130641 https://reactome.org/PathwayBrowser/#/R-SSC-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Sus scrofa 43474 R-SSC-2130725 https://reactome.org/PathwayBrowser/#/R-SSC-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Sus scrofa 43474 R-SSC-216723 https://reactome.org/PathwayBrowser/#/R-SSC-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Sus scrofa 43474 R-SSC-216757 https://reactome.org/PathwayBrowser/#/R-SSC-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Sus scrofa 43474 R-SSC-2187401 https://reactome.org/PathwayBrowser/#/R-SSC-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Sus scrofa 43474 R-SSC-2395873 https://reactome.org/PathwayBrowser/#/R-SSC-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Sus scrofa 43474 R-SSC-2395876 https://reactome.org/PathwayBrowser/#/R-SSC-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 43474 R-SSC-2395879 https://reactome.org/PathwayBrowser/#/R-SSC-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 43474 R-SSC-2395965 https://reactome.org/PathwayBrowser/#/R-SSC-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Sus scrofa 43474 R-SSC-2408551 https://reactome.org/PathwayBrowser/#/R-SSC-2408551 SeMet is converted to AdoSeMet by MAT IEA Sus scrofa 43474 R-SSC-2509793 https://reactome.org/PathwayBrowser/#/R-SSC-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Sus scrofa 43474 R-SSC-2509816 https://reactome.org/PathwayBrowser/#/R-SSC-2509816 NUDT16 hydrolyses IDP to IMP IEA Sus scrofa 43474 R-SSC-2529015 https://reactome.org/PathwayBrowser/#/R-SSC-2529015 Dephosphorylation of CK2-modified condensin I IEA Sus scrofa 43474 R-SSC-2584246 https://reactome.org/PathwayBrowser/#/R-SSC-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Sus scrofa 43474 R-SSC-265783 https://reactome.org/PathwayBrowser/#/R-SSC-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-266082 https://reactome.org/PathwayBrowser/#/R-SSC-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Sus scrofa 43474 R-SSC-2730849 https://reactome.org/PathwayBrowser/#/R-SSC-2730849 Calcineurin binds and dephosphorylates NFAT IEA Sus scrofa 43474 R-SSC-2872498 https://reactome.org/PathwayBrowser/#/R-SSC-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Sus scrofa 43474 R-SSC-2995388 https://reactome.org/PathwayBrowser/#/R-SSC-2995388 PP2A dephosphorylates BANF1 IEA Sus scrofa 43474 R-SSC-3002811 https://reactome.org/PathwayBrowser/#/R-SSC-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Sus scrofa 43474 R-SSC-3095901 https://reactome.org/PathwayBrowser/#/R-SSC-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Sus scrofa 43474 R-SSC-3257122 https://reactome.org/PathwayBrowser/#/R-SSC-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Sus scrofa 43474 R-SSC-3262512 https://reactome.org/PathwayBrowser/#/R-SSC-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Sus scrofa 43474 R-SSC-3266566 https://reactome.org/PathwayBrowser/#/R-SSC-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Sus scrofa 43474 R-SSC-3371422 https://reactome.org/PathwayBrowser/#/R-SSC-3371422 ATP hydrolysis by HSP70 IEA Sus scrofa 43474 R-SSC-372843 https://reactome.org/PathwayBrowser/#/R-SSC-372843 SLC25A10 mediates exchange of malate and phosphate IEA Sus scrofa 43474 R-SSC-377643 https://reactome.org/PathwayBrowser/#/R-SSC-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Sus scrofa 43474 R-SSC-3781011 https://reactome.org/PathwayBrowser/#/R-SSC-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Sus scrofa 43474 R-SSC-3781018 https://reactome.org/PathwayBrowser/#/R-SSC-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Sus scrofa 43474 R-SSC-380949 https://reactome.org/PathwayBrowser/#/R-SSC-380949 AMPK is dephosphorylated IEA Sus scrofa 43474 R-SSC-380979 https://reactome.org/PathwayBrowser/#/R-SSC-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Sus scrofa 43474 R-SSC-382553 https://reactome.org/PathwayBrowser/#/R-SSC-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Sus scrofa 43474 R-SSC-382560 https://reactome.org/PathwayBrowser/#/R-SSC-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Sus scrofa 43474 R-SSC-382575 https://reactome.org/PathwayBrowser/#/R-SSC-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Sus scrofa 43474 R-SSC-383190 https://reactome.org/PathwayBrowser/#/R-SSC-383190 HCO3- transport through ion channel IEA Sus scrofa 43474 R-SSC-390593 https://reactome.org/PathwayBrowser/#/R-SSC-390593 ATP Hydrolysis By Myosin IEA Sus scrofa 43474 R-SSC-4084976 https://reactome.org/PathwayBrowser/#/R-SSC-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Sus scrofa 43474 R-SSC-4084989 https://reactome.org/PathwayBrowser/#/R-SSC-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Sus scrofa 43474 R-SSC-4088141 https://reactome.org/PathwayBrowser/#/R-SSC-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Sus scrofa 43474 R-SSC-4093339 https://reactome.org/PathwayBrowser/#/R-SSC-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Sus scrofa 43474 R-SSC-416320 https://reactome.org/PathwayBrowser/#/R-SSC-416320 Trafficking of GluR1-containing AMPA receptors IEA Sus scrofa 43474 R-SSC-416546 https://reactome.org/PathwayBrowser/#/R-SSC-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Sus scrofa 43474 R-SSC-416559 https://reactome.org/PathwayBrowser/#/R-SSC-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Sus scrofa 43474 R-SSC-416639 https://reactome.org/PathwayBrowser/#/R-SSC-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Sus scrofa 43474 R-SSC-416985 https://reactome.org/PathwayBrowser/#/R-SSC-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Sus scrofa 43474 R-SSC-421007 https://reactome.org/PathwayBrowser/#/R-SSC-421007 Endocytosis of Ca impermeable AMPA receptors IEA Sus scrofa 43474 R-SSC-421831 https://reactome.org/PathwayBrowser/#/R-SSC-421831 trans-Golgi Network Coat Assembly IEA Sus scrofa 43474 R-SSC-421835 https://reactome.org/PathwayBrowser/#/R-SSC-421835 trans-Golgi Network Vesicle Scission IEA Sus scrofa 43474 R-SSC-427605 https://reactome.org/PathwayBrowser/#/R-SSC-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Sus scrofa 43474 R-SSC-427645 https://reactome.org/PathwayBrowser/#/R-SSC-427645 SLC34A3 cotransports Pi, 2Na+ IEA Sus scrofa 43474 R-SSC-427656 https://reactome.org/PathwayBrowser/#/R-SSC-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Sus scrofa 43474 R-SSC-428609 https://reactome.org/PathwayBrowser/#/R-SSC-428609 Type I Na+-coupled phosphate co-transport IEA Sus scrofa 43474 R-SSC-428664 https://reactome.org/PathwayBrowser/#/R-SSC-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Sus scrofa 43474 R-SSC-428690 https://reactome.org/PathwayBrowser/#/R-SSC-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Sus scrofa 43474 R-SSC-428696 https://reactome.org/PathwayBrowser/#/R-SSC-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Sus scrofa 43474 R-SSC-429157 https://reactome.org/PathwayBrowser/#/R-SSC-429157 ABCC4 accumulation of dense granule contents IEA Sus scrofa 43474 R-SSC-432706 https://reactome.org/PathwayBrowser/#/R-SSC-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Sus scrofa 43474 R-SSC-432707 https://reactome.org/PathwayBrowser/#/R-SSC-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Sus scrofa 43474 R-SSC-4419948 https://reactome.org/PathwayBrowser/#/R-SSC-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Sus scrofa 43474 R-SSC-445699 https://reactome.org/PathwayBrowser/#/R-SSC-445699 ATP Hydrolysis By Myosin IEA Sus scrofa 43474 R-SSC-446200 https://reactome.org/PathwayBrowser/#/R-SSC-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Sus scrofa 43474 R-SSC-449937 https://reactome.org/PathwayBrowser/#/R-SSC-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Sus scrofa 43474 R-SSC-453339 https://reactome.org/PathwayBrowser/#/R-SSC-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Sus scrofa 43474 R-SSC-4551451 https://reactome.org/PathwayBrowser/#/R-SSC-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Sus scrofa 43474 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 43474 R-SSC-504054 https://reactome.org/PathwayBrowser/#/R-SSC-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Sus scrofa 43474 R-SSC-508040 https://reactome.org/PathwayBrowser/#/R-SSC-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Sus scrofa 43474 R-SSC-508308 https://reactome.org/PathwayBrowser/#/R-SSC-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Sus scrofa 43474 R-SSC-5221130 https://reactome.org/PathwayBrowser/#/R-SSC-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Sus scrofa 43474 R-SSC-5223313 https://reactome.org/PathwayBrowser/#/R-SSC-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Sus scrofa 43474 R-SSC-5223317 https://reactome.org/PathwayBrowser/#/R-SSC-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Sus scrofa 43474 R-SSC-5251955 https://reactome.org/PathwayBrowser/#/R-SSC-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Sus scrofa 43474 R-SSC-5251959 https://reactome.org/PathwayBrowser/#/R-SSC-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Sus scrofa 43474 R-SSC-5251989 https://reactome.org/PathwayBrowser/#/R-SSC-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Sus scrofa 43474 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Sus scrofa 43474 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa 43474 R-SSC-555065 https://reactome.org/PathwayBrowser/#/R-SSC-555065 Formation of clathrin coated vesicle IEA Sus scrofa 43474 R-SSC-5603114 https://reactome.org/PathwayBrowser/#/R-SSC-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Sus scrofa 43474 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 43474 R-SSC-5623513 https://reactome.org/PathwayBrowser/#/R-SSC-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Sus scrofa 43474 R-SSC-5628905 https://reactome.org/PathwayBrowser/#/R-SSC-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Sus scrofa 43474 R-SSC-5649705 https://reactome.org/PathwayBrowser/#/R-SSC-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Sus scrofa 43474 R-SSC-5665809 https://reactome.org/PathwayBrowser/#/R-SSC-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Sus scrofa 43474 R-SSC-5672957 https://reactome.org/PathwayBrowser/#/R-SSC-5672957 PP2A dephosphorylates KSR1 IEA Sus scrofa 43474 R-SSC-5672961 https://reactome.org/PathwayBrowser/#/R-SSC-5672961 PP2A dephosphorylates inactive RAFs IEA Sus scrofa 43474 R-SSC-5675373 https://reactome.org/PathwayBrowser/#/R-SSC-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Sus scrofa 43474 R-SSC-5675376 https://reactome.org/PathwayBrowser/#/R-SSC-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Sus scrofa 43474 R-SSC-5675431 https://reactome.org/PathwayBrowser/#/R-SSC-5675431 PP2A dephosphorylates RAF1 IEA Sus scrofa 43474 R-SSC-5675433 https://reactome.org/PathwayBrowser/#/R-SSC-5675433 PP5 dephosphorylates RAF1 S338 IEA Sus scrofa 43474 R-SSC-5678706 https://reactome.org/PathwayBrowser/#/R-SSC-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Sus scrofa 43474 R-SSC-5678863 https://reactome.org/PathwayBrowser/#/R-SSC-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-5679041 https://reactome.org/PathwayBrowser/#/R-SSC-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-5682285 https://reactome.org/PathwayBrowser/#/R-SSC-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-5683405 https://reactome.org/PathwayBrowser/#/R-SSC-5683405 PPP5C dephosphorylates TP53BP1 IEA Sus scrofa 43474 R-SSC-5683714 https://reactome.org/PathwayBrowser/#/R-SSC-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Sus scrofa 43474 R-SSC-5683925 https://reactome.org/PathwayBrowser/#/R-SSC-5683925 ULK1 is dephosphorylated IEA Sus scrofa 43474 R-SSC-5683967 https://reactome.org/PathwayBrowser/#/R-SSC-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Sus scrofa 43474 R-SSC-5687758 https://reactome.org/PathwayBrowser/#/R-SSC-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Sus scrofa 43474 R-SSC-5690996 https://reactome.org/PathwayBrowser/#/R-SSC-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Sus scrofa 43474 R-SSC-5692462 https://reactome.org/PathwayBrowser/#/R-SSC-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Sus scrofa 43474 R-SSC-5692480 https://reactome.org/PathwayBrowser/#/R-SSC-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Sus scrofa 43474 R-SSC-5692754 https://reactome.org/PathwayBrowser/#/R-SSC-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Sus scrofa 43474 R-SSC-5693153 https://reactome.org/PathwayBrowser/#/R-SSC-5693153 PPM1K dephosphorylates p-BCKDH IEA Sus scrofa 43474 R-SSC-5694126 https://reactome.org/PathwayBrowser/#/R-SSC-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Sus scrofa 43474 R-SSC-5694421 https://reactome.org/PathwayBrowser/#/R-SSC-5694421 PP6 dephosphorylates SEC24 IEA Sus scrofa 43474 R-SSC-5694425 https://reactome.org/PathwayBrowser/#/R-SSC-5694425 NSF ATPase activity dissociates cis-SNARE IEA Sus scrofa 43474 R-SSC-5694527 https://reactome.org/PathwayBrowser/#/R-SSC-5694527 Loss of SAR1B GTPase IEA Sus scrofa 43474 R-SSC-5696408 https://reactome.org/PathwayBrowser/#/R-SSC-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Sus scrofa 43474 R-SSC-5696415 https://reactome.org/PathwayBrowser/#/R-SSC-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Sus scrofa 43474 R-SSC-5696839 https://reactome.org/PathwayBrowser/#/R-SSC-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Sus scrofa 43474 R-SSC-6782131 https://reactome.org/PathwayBrowser/#/R-SSC-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa 43474 R-SSC-6786245 https://reactome.org/PathwayBrowser/#/R-SSC-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Sus scrofa 43474 R-SSC-6788295 https://reactome.org/PathwayBrowser/#/R-SSC-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Sus scrofa 43474 R-SSC-6788912 https://reactome.org/PathwayBrowser/#/R-SSC-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Sus scrofa 43474 R-SSC-6792863 https://reactome.org/PathwayBrowser/#/R-SSC-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Sus scrofa 43474 R-SSC-6797630 https://reactome.org/PathwayBrowser/#/R-SSC-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Sus scrofa 43474 R-SSC-6801342 https://reactome.org/PathwayBrowser/#/R-SSC-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Sus scrofa 43474 R-SSC-6801456 https://reactome.org/PathwayBrowser/#/R-SSC-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Sus scrofa 43474 R-SSC-6803545 https://reactome.org/PathwayBrowser/#/R-SSC-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Sus scrofa 43474 R-SSC-6806967 https://reactome.org/PathwayBrowser/#/R-SSC-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Sus scrofa 43474 R-SSC-6807027 https://reactome.org/PathwayBrowser/#/R-SSC-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Sus scrofa 43474 R-SSC-6809015 https://reactome.org/PathwayBrowser/#/R-SSC-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Sus scrofa 43474 R-SSC-6809320 https://reactome.org/PathwayBrowser/#/R-SSC-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Sus scrofa 43474 R-SSC-6809325 https://reactome.org/PathwayBrowser/#/R-SSC-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Sus scrofa 43474 R-SSC-6809720 https://reactome.org/PathwayBrowser/#/R-SSC-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Sus scrofa 43474 R-SSC-6809777 https://reactome.org/PathwayBrowser/#/R-SSC-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Sus scrofa 43474 R-SSC-6809778 https://reactome.org/PathwayBrowser/#/R-SSC-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Sus scrofa 43474 R-SSC-6810410 https://reactome.org/PathwayBrowser/#/R-SSC-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Sus scrofa 43474 R-SSC-6811422 https://reactome.org/PathwayBrowser/#/R-SSC-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Sus scrofa 43474 R-SSC-6814120 https://reactome.org/PathwayBrowser/#/R-SSC-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Sus scrofa 43474 R-SSC-68954 https://reactome.org/PathwayBrowser/#/R-SSC-68954 Mcm2-7 is phosphorylated by DDK IEA Sus scrofa 43474 R-SSC-69199 https://reactome.org/PathwayBrowser/#/R-SSC-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Sus scrofa 43474 R-SSC-70262 https://reactome.org/PathwayBrowser/#/R-SSC-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Sus scrofa 43474 R-SSC-70449 https://reactome.org/PathwayBrowser/#/R-SSC-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Sus scrofa 43474 R-SSC-70479 https://reactome.org/PathwayBrowser/#/R-SSC-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Sus scrofa 43474 R-SSC-70482 https://reactome.org/PathwayBrowser/#/R-SSC-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Sus scrofa 43474 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 43474 R-SSC-70555 https://reactome.org/PathwayBrowser/#/R-SSC-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Sus scrofa 43474 R-SSC-70560 https://reactome.org/PathwayBrowser/#/R-SSC-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Sus scrofa 43474 R-SSC-70606 https://reactome.org/PathwayBrowser/#/R-SSC-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Sus scrofa 43474 R-SSC-70773 https://reactome.org/PathwayBrowser/#/R-SSC-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Sus scrofa 43474 R-SSC-70997 https://reactome.org/PathwayBrowser/#/R-SSC-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Sus scrofa 43474 R-SSC-71031 https://reactome.org/PathwayBrowser/#/R-SSC-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Sus scrofa 43474 R-SSC-71590 https://reactome.org/PathwayBrowser/#/R-SSC-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Sus scrofa 43474 R-SSC-71732 https://reactome.org/PathwayBrowser/#/R-SSC-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Sus scrofa 43474 R-SSC-71775 https://reactome.org/PathwayBrowser/#/R-SSC-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Sus scrofa 43474 R-SSC-71825 https://reactome.org/PathwayBrowser/#/R-SSC-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Sus scrofa 43474 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa 43474 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa 43474 R-SSC-73573 https://reactome.org/PathwayBrowser/#/R-SSC-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Sus scrofa 43474 R-SSC-73577 https://reactome.org/PathwayBrowser/#/R-SSC-73577 CAD hexamer transforms L-Gln to CAP IEA Sus scrofa 43474 R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa 43474 R-SSC-73805 https://reactome.org/PathwayBrowser/#/R-SSC-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Sus scrofa 43474 R-SSC-73810 https://reactome.org/PathwayBrowser/#/R-SSC-73810 FGAM + ATP => AIR + ADP + Pi IEA Sus scrofa 43474 R-SSC-73814 https://reactome.org/PathwayBrowser/#/R-SSC-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Sus scrofa 43474 R-SSC-74242 https://reactome.org/PathwayBrowser/#/R-SSC-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Sus scrofa 43474 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 43474 R-SSC-74249 https://reactome.org/PathwayBrowser/#/R-SSC-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Sus scrofa 43474 R-SSC-74372 https://reactome.org/PathwayBrowser/#/R-SSC-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Sus scrofa 43474 R-SSC-74376 https://reactome.org/PathwayBrowser/#/R-SSC-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Sus scrofa 43474 R-SSC-74733 https://reactome.org/PathwayBrowser/#/R-SSC-74733 Insulin receptor de-phosphorylation IEA Sus scrofa 43474 R-SSC-74948 https://reactome.org/PathwayBrowser/#/R-SSC-74948 PP2A dephosphorylates p-RHO to RHO IEA Sus scrofa 43474 R-SSC-75848 https://reactome.org/PathwayBrowser/#/R-SSC-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Sus scrofa 43474 R-SSC-75851 https://reactome.org/PathwayBrowser/#/R-SSC-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 43474 R-SSC-75899 https://reactome.org/PathwayBrowser/#/R-SSC-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Sus scrofa 43474 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa 43474 R-SSC-77078 https://reactome.org/PathwayBrowser/#/R-SSC-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Sus scrofa 43474 R-SSC-8848053 https://reactome.org/PathwayBrowser/#/R-SSC-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Sus scrofa 43474 R-SSC-8849082 https://reactome.org/PathwayBrowser/#/R-SSC-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Sus scrofa 43474 R-SSC-8849435 https://reactome.org/PathwayBrowser/#/R-SSC-8849435 PTPN1 dephosphorylates PTK6 IEA Sus scrofa 43474 R-SSC-8849969 https://reactome.org/PathwayBrowser/#/R-SSC-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Sus scrofa 43474 R-SSC-8850846 https://reactome.org/PathwayBrowser/#/R-SSC-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Sus scrofa 43474 R-SSC-8850854 https://reactome.org/PathwayBrowser/#/R-SSC-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Sus scrofa 43474 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 43474 R-SSC-8851110 https://reactome.org/PathwayBrowser/#/R-SSC-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Sus scrofa 43474 R-SSC-8851129 https://reactome.org/PathwayBrowser/#/R-SSC-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Sus scrofa 43474 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 43474 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 43474 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 43474 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 43474 R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 43474 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 43474 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 43474 R-SSC-8852200 https://reactome.org/PathwayBrowser/#/R-SSC-8852200 Inactivation of LCK by PTPN22 IEA Sus scrofa 43474 R-SSC-8854173 https://reactome.org/PathwayBrowser/#/R-SSC-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Sus scrofa 43474 R-SSC-8854255 https://reactome.org/PathwayBrowser/#/R-SSC-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 43474 R-SSC-8854329 https://reactome.org/PathwayBrowser/#/R-SSC-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 43474 R-SSC-8854604 https://reactome.org/PathwayBrowser/#/R-SSC-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Sus scrofa 43474 R-SSC-8854612 https://reactome.org/PathwayBrowser/#/R-SSC-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Sus scrofa 43474 R-SSC-8855381 https://reactome.org/PathwayBrowser/#/R-SSC-8855381 PTPN22 dephosphorylates ZAP70 IEA Sus scrofa 43474 R-SSC-8863804 https://reactome.org/PathwayBrowser/#/R-SSC-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Sus scrofa 43474 R-SSC-8864029 https://reactome.org/PathwayBrowser/#/R-SSC-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Sus scrofa 43474 R-SSC-8864036 https://reactome.org/PathwayBrowser/#/R-SSC-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Sus scrofa 43474 R-SSC-8864125 https://reactome.org/PathwayBrowser/#/R-SSC-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Sus scrofa 43474 R-SSC-8865774 https://reactome.org/PathwayBrowser/#/R-SSC-8865774 TTLLs polyglutamylate tubulin IEA Sus scrofa 43474 R-SSC-8866542 https://reactome.org/PathwayBrowser/#/R-SSC-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Sus scrofa 43474 R-SSC-8867047 https://reactome.org/PathwayBrowser/#/R-SSC-8867047 PTPN3 dephosphorylates EPS15 IEA Sus scrofa 43474 R-SSC-8867370 https://reactome.org/PathwayBrowser/#/R-SSC-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Sus scrofa 43474 R-SSC-8867658 https://reactome.org/PathwayBrowser/#/R-SSC-8867658 PTPN3 dephosphorylates MAPK12 IEA Sus scrofa 43474 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 43474 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 43474 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 43474 R-SSC-8876889 https://reactome.org/PathwayBrowser/#/R-SSC-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 43474 R-SSC-8878654 https://reactome.org/PathwayBrowser/#/R-SSC-8878654 ACP6 hydrolyses MYS-LPA IEA Sus scrofa 43474 R-SSC-8878787 https://reactome.org/PathwayBrowser/#/R-SSC-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Sus scrofa 43474 R-SSC-8937767 https://reactome.org/PathwayBrowser/#/R-SSC-8937767 PTPN11 dephosphorylates RUNX1 IEA Sus scrofa 43474 R-SSC-8940070 https://reactome.org/PathwayBrowser/#/R-SSC-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Sus scrofa 43474 R-SSC-8940074 https://reactome.org/PathwayBrowser/#/R-SSC-8940074 NT5E:Zn2+ hydrolyses NMN IEA Sus scrofa 43474 R-SSC-8951498 https://reactome.org/PathwayBrowser/#/R-SSC-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Sus scrofa 43474 R-SSC-8952137 https://reactome.org/PathwayBrowser/#/R-SSC-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Sus scrofa 43474 R-SSC-8953499 https://reactome.org/PathwayBrowser/#/R-SSC-8953499 IMPAD1 hydrolyses PAP to AMP IEA Sus scrofa 43474 R-SSC-8959510 https://reactome.org/PathwayBrowser/#/R-SSC-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Sus scrofa 43474 R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa 43474 R-SSC-8982020 https://reactome.org/PathwayBrowser/#/R-SSC-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Sus scrofa 43474 R-SSC-8982021 https://reactome.org/PathwayBrowser/#/R-SSC-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Sus scrofa 43474 R-SSC-8982025 https://reactome.org/PathwayBrowser/#/R-SSC-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Sus scrofa 43474 R-SSC-8985594 https://reactome.org/PathwayBrowser/#/R-SSC-8985594 MYO9B inactivates RHOA IEA Sus scrofa 43474 R-SSC-9013022 https://reactome.org/PathwayBrowser/#/R-SSC-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Sus scrofa 43474 R-SSC-9013111 https://reactome.org/PathwayBrowser/#/R-SSC-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Sus scrofa 43474 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa 43474 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa 43474 R-SSC-9013437 https://reactome.org/PathwayBrowser/#/R-SSC-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Sus scrofa 43474 R-SSC-9014295 https://reactome.org/PathwayBrowser/#/R-SSC-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Sus scrofa 43474 R-SSC-9014434 https://reactome.org/PathwayBrowser/#/R-SSC-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Sus scrofa 43474 R-SSC-9017488 https://reactome.org/PathwayBrowser/#/R-SSC-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Sus scrofa 43474 R-SSC-9018745 https://reactome.org/PathwayBrowser/#/R-SSC-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Sus scrofa 43474 R-SSC-9018806 https://reactome.org/PathwayBrowser/#/R-SSC-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Sus scrofa 43474 R-SSC-9018814 https://reactome.org/PathwayBrowser/#/R-SSC-9018814 RHOT1 hydrolyzes GTP IEA Sus scrofa 43474 R-SSC-9018826 https://reactome.org/PathwayBrowser/#/R-SSC-9018826 RHOT2 hydrolyzes GTP IEA Sus scrofa 43474 R-SSC-9038161 https://reactome.org/PathwayBrowser/#/R-SSC-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Sus scrofa 43474 R-SSC-917693 https://reactome.org/PathwayBrowser/#/R-SSC-917693 ESCRT Disassembly IEA Sus scrofa 43474 R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa 43474 R-SSC-917979 https://reactome.org/PathwayBrowser/#/R-SSC-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-936802 https://reactome.org/PathwayBrowser/#/R-SSC-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Sus scrofa 43474 R-SSC-936883 https://reactome.org/PathwayBrowser/#/R-SSC-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Sus scrofa 43474 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 43474 R-SSC-937311 https://reactome.org/PathwayBrowser/#/R-SSC-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Sus scrofa 43474 R-SSC-939763 https://reactome.org/PathwayBrowser/#/R-SSC-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Sus scrofa 43474 R-SSC-947591 https://reactome.org/PathwayBrowser/#/R-SSC-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Sus scrofa 43474 R-SSC-9624893 https://reactome.org/PathwayBrowser/#/R-SSC-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Sus scrofa 43474 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa 43474 R-SSC-9645598 https://reactome.org/PathwayBrowser/#/R-SSC-9645598 RRAGC,D hydrolyzes GTP IEA Sus scrofa 43474 R-SSC-965067 https://reactome.org/PathwayBrowser/#/R-SSC-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Sus scrofa 43474 R-SSC-9658445 https://reactome.org/PathwayBrowser/#/R-SSC-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Sus scrofa 43474 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 43474 R-SSC-9661417 https://reactome.org/PathwayBrowser/#/R-SSC-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa 43474 R-SSC-9674816 https://reactome.org/PathwayBrowser/#/R-SSC-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Sus scrofa 43474 R-SSC-9684118 https://reactome.org/PathwayBrowser/#/R-SSC-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa 43474 R-SSC-9686524 https://reactome.org/PathwayBrowser/#/R-SSC-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Sus scrofa 43474 R-SSC-9693282 https://reactome.org/PathwayBrowser/#/R-SSC-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Sus scrofa 43474 R-SSC-9700200 https://reactome.org/PathwayBrowser/#/R-SSC-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Sus scrofa 43474 R-SSC-9701507 https://reactome.org/PathwayBrowser/#/R-SSC-9701507 PTPN6 dephosphorylates JAK3 IEA Sus scrofa 43474 R-SSC-9727198 https://reactome.org/PathwayBrowser/#/R-SSC-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Sus scrofa 43474 R-SSC-9750546 https://reactome.org/PathwayBrowser/#/R-SSC-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-9750656 https://reactome.org/PathwayBrowser/#/R-SSC-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Sus scrofa 43474 R-SSC-9753278 https://reactome.org/PathwayBrowser/#/R-SSC-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 43474 R-SSC-9753283 https://reactome.org/PathwayBrowser/#/R-SSC-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 43474 R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 43474 R-SSC-9759206 https://reactome.org/PathwayBrowser/#/R-SSC-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Sus scrofa 43474 R-SSC-9759454 https://reactome.org/PathwayBrowser/#/R-SSC-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Sus scrofa 43474 R-SSC-9759461 https://reactome.org/PathwayBrowser/#/R-SSC-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Sus scrofa 43474 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa 43474 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa 43474 R-SSC-977324 https://reactome.org/PathwayBrowser/#/R-SSC-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Sus scrofa 43474 R-SSC-983144 https://reactome.org/PathwayBrowser/#/R-SSC-983144 Transport of Antigen peptide in to ER IEA Sus scrofa 43474 R-SSC-9837419 https://reactome.org/PathwayBrowser/#/R-SSC-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Sus scrofa 43474 R-SSC-9838004 https://reactome.org/PathwayBrowser/#/R-SSC-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Sus scrofa 43474 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa 43474 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa 43474 R-SSC-9839059 https://reactome.org/PathwayBrowser/#/R-SSC-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Sus scrofa 43474 R-SSC-9839105 https://reactome.org/PathwayBrowser/#/R-SSC-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Sus scrofa 43474 R-SSC-9839113 https://reactome.org/PathwayBrowser/#/R-SSC-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Sus scrofa 43474 R-SSC-9843721 https://reactome.org/PathwayBrowser/#/R-SSC-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Sus scrofa 43474 R-SSC-9853385 https://reactome.org/PathwayBrowser/#/R-SSC-9853385 PPP1CC dephosphorylates PLK1 IEA Sus scrofa 43474 R-SSC-9861725 https://reactome.org/PathwayBrowser/#/R-SSC-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Sus scrofa 43474 R-SSC-997309 https://reactome.org/PathwayBrowser/#/R-SSC-997309 Dephosphorylation of STAT1 by SHP2 IEA Sus scrofa 43474 R-SSC-997311 https://reactome.org/PathwayBrowser/#/R-SSC-997311 Dephosphorylation of TYK2 by PTP1B IEA Sus scrofa 43474 R-SSC-997314 https://reactome.org/PathwayBrowser/#/R-SSC-997314 Dephosphorylation of JAK1 by SHP1 IEA Sus scrofa 43474 R-SSC-997326 https://reactome.org/PathwayBrowser/#/R-SSC-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Sus scrofa 43474 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 43474 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 43474 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 43474 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 43474 R-XTR-109415 https://reactome.org/PathwayBrowser/#/R-XTR-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Xenopus tropicalis 43474 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 43474 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 43474 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 43474 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 43474 R-XTR-111215 https://reactome.org/PathwayBrowser/#/R-XTR-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Xenopus tropicalis 43474 R-XTR-111524 https://reactome.org/PathwayBrowser/#/R-XTR-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Xenopus tropicalis 43474 R-XTR-112033 https://reactome.org/PathwayBrowser/#/R-XTR-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Xenopus tropicalis 43474 R-XTR-112034 https://reactome.org/PathwayBrowser/#/R-XTR-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Xenopus tropicalis 43474 R-XTR-112037 https://reactome.org/PathwayBrowser/#/R-XTR-112037 Inactivation of PLC beta IEA Xenopus tropicalis 43474 R-XTR-112265 https://reactome.org/PathwayBrowser/#/R-XTR-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Xenopus tropicalis 43474 R-XTR-112266 https://reactome.org/PathwayBrowser/#/R-XTR-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Xenopus tropicalis 43474 R-XTR-1237129 https://reactome.org/PathwayBrowser/#/R-XTR-1237129 Acireductone is created IEA Xenopus tropicalis 43474 R-XTR-1237160 https://reactome.org/PathwayBrowser/#/R-XTR-1237160 MTA is cleaved and phosphorylated IEA Xenopus tropicalis 43474 R-XTR-1247935 https://reactome.org/PathwayBrowser/#/R-XTR-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Xenopus tropicalis 43474 R-XTR-1295632 https://reactome.org/PathwayBrowser/#/R-XTR-1295632 PPA2A dephosphorylates SPRY2 IEA Xenopus tropicalis 43474 R-XTR-1363274 https://reactome.org/PathwayBrowser/#/R-XTR-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Xenopus tropicalis 43474 R-XTR-1363276 https://reactome.org/PathwayBrowser/#/R-XTR-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Xenopus tropicalis 43474 R-XTR-1369065 https://reactome.org/PathwayBrowser/#/R-XTR-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Xenopus tropicalis 43474 R-XTR-139906 https://reactome.org/PathwayBrowser/#/R-XTR-139906 Activation of BAD by calcineurin IEA Xenopus tropicalis 43474 R-XTR-1454916 https://reactome.org/PathwayBrowser/#/R-XTR-1454916 The ABCC family mediates organic anion transport IEA Xenopus tropicalis 43474 R-XTR-1454928 https://reactome.org/PathwayBrowser/#/R-XTR-1454928 ABCG4 may mediate cholesterol efflux IEA Xenopus tropicalis 43474 R-XTR-1467466 https://reactome.org/PathwayBrowser/#/R-XTR-1467466 ABCA4 mediates atRAL transport IEA Xenopus tropicalis 43474 R-XTR-1483096 https://reactome.org/PathwayBrowser/#/R-XTR-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Xenopus tropicalis 43474 R-XTR-1483159 https://reactome.org/PathwayBrowser/#/R-XTR-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Xenopus tropicalis 43474 R-XTR-1483203 https://reactome.org/PathwayBrowser/#/R-XTR-1483203 PA is dephosphorylated to DAG by LPIN IEA Xenopus tropicalis 43474 R-XTR-1638821 https://reactome.org/PathwayBrowser/#/R-XTR-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Xenopus tropicalis 43474 R-XTR-1675795 https://reactome.org/PathwayBrowser/#/R-XTR-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Xenopus tropicalis 43474 R-XTR-1675824 https://reactome.org/PathwayBrowser/#/R-XTR-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Xenopus tropicalis 43474 R-XTR-1675836 https://reactome.org/PathwayBrowser/#/R-XTR-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-1675949 https://reactome.org/PathwayBrowser/#/R-XTR-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-1675988 https://reactome.org/PathwayBrowser/#/R-XTR-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-1675994 https://reactome.org/PathwayBrowser/#/R-XTR-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-1676065 https://reactome.org/PathwayBrowser/#/R-XTR-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Xenopus tropicalis 43474 R-XTR-1676105 https://reactome.org/PathwayBrowser/#/R-XTR-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Xenopus tropicalis 43474 R-XTR-1676141 https://reactome.org/PathwayBrowser/#/R-XTR-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Xenopus tropicalis 43474 R-XTR-1676149 https://reactome.org/PathwayBrowser/#/R-XTR-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-1676162 https://reactome.org/PathwayBrowser/#/R-XTR-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Xenopus tropicalis 43474 R-XTR-1676164 https://reactome.org/PathwayBrowser/#/R-XTR-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-1676177 https://reactome.org/PathwayBrowser/#/R-XTR-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-1676203 https://reactome.org/PathwayBrowser/#/R-XTR-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-1676204 https://reactome.org/PathwayBrowser/#/R-XTR-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Xenopus tropicalis 43474 R-XTR-170153 https://reactome.org/PathwayBrowser/#/R-XTR-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Xenopus tropicalis 43474 R-XTR-170158 https://reactome.org/PathwayBrowser/#/R-XTR-170158 Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes IEA Xenopus tropicalis 43474 R-XTR-170161 https://reactome.org/PathwayBrowser/#/R-XTR-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Xenopus tropicalis 43474 R-XTR-170666 https://reactome.org/PathwayBrowser/#/R-XTR-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Xenopus tropicalis 43474 R-XTR-170685 https://reactome.org/PathwayBrowser/#/R-XTR-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Xenopus tropicalis 43474 R-XTR-170686 https://reactome.org/PathwayBrowser/#/R-XTR-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Xenopus tropicalis 43474 R-XTR-174110 https://reactome.org/PathwayBrowser/#/R-XTR-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Xenopus tropicalis 43474 R-XTR-174367 https://reactome.org/PathwayBrowser/#/R-XTR-174367 GCL ligates L-Glu to L-Cys IEA Xenopus tropicalis 43474 R-XTR-174391 https://reactome.org/PathwayBrowser/#/R-XTR-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Xenopus tropicalis 43474 R-XTR-174439 https://reactome.org/PathwayBrowser/#/R-XTR-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Xenopus tropicalis 43474 R-XTR-176606 https://reactome.org/PathwayBrowser/#/R-XTR-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Xenopus tropicalis 43474 R-XTR-177924 https://reactome.org/PathwayBrowser/#/R-XTR-177924 Dephosphorylation of Gab1 by SHP2 IEA Xenopus tropicalis 43474 R-XTR-177926 https://reactome.org/PathwayBrowser/#/R-XTR-177926 Dephosphorylation of PAG by SHP2 IEA Xenopus tropicalis 43474 R-XTR-177935 https://reactome.org/PathwayBrowser/#/R-XTR-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Xenopus tropicalis 43474 R-XTR-1855154 https://reactome.org/PathwayBrowser/#/R-XTR-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855159 https://reactome.org/PathwayBrowser/#/R-XTR-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855163 https://reactome.org/PathwayBrowser/#/R-XTR-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Xenopus tropicalis 43474 R-XTR-1855165 https://reactome.org/PathwayBrowser/#/R-XTR-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855166 https://reactome.org/PathwayBrowser/#/R-XTR-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855171 https://reactome.org/PathwayBrowser/#/R-XTR-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855174 https://reactome.org/PathwayBrowser/#/R-XTR-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855180 https://reactome.org/PathwayBrowser/#/R-XTR-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855198 https://reactome.org/PathwayBrowser/#/R-XTR-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855200 https://reactome.org/PathwayBrowser/#/R-XTR-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Xenopus tropicalis 43474 R-XTR-1855202 https://reactome.org/PathwayBrowser/#/R-XTR-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855205 https://reactome.org/PathwayBrowser/#/R-XTR-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855210 https://reactome.org/PathwayBrowser/#/R-XTR-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855211 https://reactome.org/PathwayBrowser/#/R-XTR-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855213 https://reactome.org/PathwayBrowser/#/R-XTR-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-1855218 https://reactome.org/PathwayBrowser/#/R-XTR-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855219 https://reactome.org/PathwayBrowser/#/R-XTR-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 43474 R-XTR-1855222 https://reactome.org/PathwayBrowser/#/R-XTR-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-1855225 https://reactome.org/PathwayBrowser/#/R-XTR-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Xenopus tropicalis 43474 R-XTR-191414 https://reactome.org/PathwayBrowser/#/R-XTR-191414 MVD decarboxylates MVA5PP to IPPP IEA Xenopus tropicalis 43474 R-XTR-194153 https://reactome.org/PathwayBrowser/#/R-XTR-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 43474 R-XTR-197958 https://reactome.org/PathwayBrowser/#/R-XTR-197958 FPGS-2 transforms THF to THFPG IEA Xenopus tropicalis 43474 R-XTR-198513 https://reactome.org/PathwayBrowser/#/R-XTR-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Xenopus tropicalis 43474 R-XTR-199456 https://reactome.org/PathwayBrowser/#/R-XTR-199456 PTEN dephosphorylates PIP3 IEA Xenopus tropicalis 43474 R-XTR-200555 https://reactome.org/PathwayBrowser/#/R-XTR-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Xenopus tropicalis 43474 R-XTR-200681 https://reactome.org/PathwayBrowser/#/R-XTR-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Xenopus tropicalis 43474 R-XTR-200682 https://reactome.org/PathwayBrowser/#/R-XTR-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Xenopus tropicalis 43474 R-XTR-200711 https://reactome.org/PathwayBrowser/#/R-XTR-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Xenopus tropicalis 43474 R-XTR-202237 https://reactome.org/PathwayBrowser/#/R-XTR-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Xenopus tropicalis 43474 R-XTR-2023971 https://reactome.org/PathwayBrowser/#/R-XTR-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 43474 R-XTR-2023973 https://reactome.org/PathwayBrowser/#/R-XTR-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 43474 R-XTR-2029468 https://reactome.org/PathwayBrowser/#/R-XTR-2029468 Conversion of PA into DAG by PAP-1 IEA Xenopus tropicalis 43474 R-XTR-203797 https://reactome.org/PathwayBrowser/#/R-XTR-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Xenopus tropicalis 43474 R-XTR-2046093 https://reactome.org/PathwayBrowser/#/R-XTR-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Xenopus tropicalis 43474 R-XTR-2130641 https://reactome.org/PathwayBrowser/#/R-XTR-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Xenopus tropicalis 43474 R-XTR-2187401 https://reactome.org/PathwayBrowser/#/R-XTR-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Xenopus tropicalis 43474 R-XTR-2395873 https://reactome.org/PathwayBrowser/#/R-XTR-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Xenopus tropicalis 43474 R-XTR-2395876 https://reactome.org/PathwayBrowser/#/R-XTR-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 43474 R-XTR-2395879 https://reactome.org/PathwayBrowser/#/R-XTR-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 43474 R-XTR-2395965 https://reactome.org/PathwayBrowser/#/R-XTR-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Xenopus tropicalis 43474 R-XTR-2408551 https://reactome.org/PathwayBrowser/#/R-XTR-2408551 SeMet is converted to AdoSeMet by MAT IEA Xenopus tropicalis 43474 R-XTR-2509793 https://reactome.org/PathwayBrowser/#/R-XTR-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Xenopus tropicalis 43474 R-XTR-2509816 https://reactome.org/PathwayBrowser/#/R-XTR-2509816 NUDT16 hydrolyses IDP to IMP IEA Xenopus tropicalis 43474 R-XTR-2584246 https://reactome.org/PathwayBrowser/#/R-XTR-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Xenopus tropicalis 43474 R-XTR-266082 https://reactome.org/PathwayBrowser/#/R-XTR-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Xenopus tropicalis 43474 R-XTR-3002811 https://reactome.org/PathwayBrowser/#/R-XTR-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Xenopus tropicalis 43474 R-XTR-3095901 https://reactome.org/PathwayBrowser/#/R-XTR-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Xenopus tropicalis 43474 R-XTR-3257122 https://reactome.org/PathwayBrowser/#/R-XTR-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Xenopus tropicalis 43474 R-XTR-3371422 https://reactome.org/PathwayBrowser/#/R-XTR-3371422 ATP hydrolysis by HSP70 IEA Xenopus tropicalis 43474 R-XTR-380979 https://reactome.org/PathwayBrowser/#/R-XTR-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Xenopus tropicalis 43474 R-XTR-382560 https://reactome.org/PathwayBrowser/#/R-XTR-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Xenopus tropicalis 43474 R-XTR-382575 https://reactome.org/PathwayBrowser/#/R-XTR-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Xenopus tropicalis 43474 R-XTR-383190 https://reactome.org/PathwayBrowser/#/R-XTR-383190 HCO3- transport through ion channel IEA Xenopus tropicalis 43474 R-XTR-4084976 https://reactome.org/PathwayBrowser/#/R-XTR-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Xenopus tropicalis 43474 R-XTR-4084989 https://reactome.org/PathwayBrowser/#/R-XTR-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Xenopus tropicalis 43474 R-XTR-4088141 https://reactome.org/PathwayBrowser/#/R-XTR-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Xenopus tropicalis 43474 R-XTR-4093339 https://reactome.org/PathwayBrowser/#/R-XTR-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Xenopus tropicalis 43474 R-XTR-416546 https://reactome.org/PathwayBrowser/#/R-XTR-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Xenopus tropicalis 43474 R-XTR-416559 https://reactome.org/PathwayBrowser/#/R-XTR-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Xenopus tropicalis 43474 R-XTR-421835 https://reactome.org/PathwayBrowser/#/R-XTR-421835 trans-Golgi Network Vesicle Scission IEA Xenopus tropicalis 43474 R-XTR-427605 https://reactome.org/PathwayBrowser/#/R-XTR-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 43474 R-XTR-427645 https://reactome.org/PathwayBrowser/#/R-XTR-427645 SLC34A3 cotransports Pi, 2Na+ IEA Xenopus tropicalis 43474 R-XTR-428664 https://reactome.org/PathwayBrowser/#/R-XTR-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Xenopus tropicalis 43474 R-XTR-428696 https://reactome.org/PathwayBrowser/#/R-XTR-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Xenopus tropicalis 43474 R-XTR-432707 https://reactome.org/PathwayBrowser/#/R-XTR-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Xenopus tropicalis 43474 R-XTR-4419948 https://reactome.org/PathwayBrowser/#/R-XTR-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Xenopus tropicalis 43474 R-XTR-446200 https://reactome.org/PathwayBrowser/#/R-XTR-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Xenopus tropicalis 43474 R-XTR-453339 https://reactome.org/PathwayBrowser/#/R-XTR-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Xenopus tropicalis 43474 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 43474 R-XTR-508040 https://reactome.org/PathwayBrowser/#/R-XTR-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Xenopus tropicalis 43474 R-XTR-508308 https://reactome.org/PathwayBrowser/#/R-XTR-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Xenopus tropicalis 43474 R-XTR-5221130 https://reactome.org/PathwayBrowser/#/R-XTR-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Xenopus tropicalis 43474 R-XTR-5251955 https://reactome.org/PathwayBrowser/#/R-XTR-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Xenopus tropicalis 43474 R-XTR-5251959 https://reactome.org/PathwayBrowser/#/R-XTR-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Xenopus tropicalis 43474 R-XTR-5251989 https://reactome.org/PathwayBrowser/#/R-XTR-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Xenopus tropicalis 43474 R-XTR-5603114 https://reactome.org/PathwayBrowser/#/R-XTR-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Xenopus tropicalis 43474 R-XTR-5628905 https://reactome.org/PathwayBrowser/#/R-XTR-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Xenopus tropicalis 43474 R-XTR-5649705 https://reactome.org/PathwayBrowser/#/R-XTR-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Xenopus tropicalis 43474 R-XTR-5675373 https://reactome.org/PathwayBrowser/#/R-XTR-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Xenopus tropicalis 43474 R-XTR-5675376 https://reactome.org/PathwayBrowser/#/R-XTR-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Xenopus tropicalis 43474 R-XTR-5675433 https://reactome.org/PathwayBrowser/#/R-XTR-5675433 PP5 dephosphorylates RAF1 S338 IEA Xenopus tropicalis 43474 R-XTR-5678863 https://reactome.org/PathwayBrowser/#/R-XTR-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Xenopus tropicalis 43474 R-XTR-5679041 https://reactome.org/PathwayBrowser/#/R-XTR-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 43474 R-XTR-5683714 https://reactome.org/PathwayBrowser/#/R-XTR-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Xenopus tropicalis 43474 R-XTR-5683925 https://reactome.org/PathwayBrowser/#/R-XTR-5683925 ULK1 is dephosphorylated IEA Xenopus tropicalis 43474 R-XTR-5687758 https://reactome.org/PathwayBrowser/#/R-XTR-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Xenopus tropicalis 43474 R-XTR-5690996 https://reactome.org/PathwayBrowser/#/R-XTR-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Xenopus tropicalis 43474 R-XTR-5692462 https://reactome.org/PathwayBrowser/#/R-XTR-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Xenopus tropicalis 43474 R-XTR-5692480 https://reactome.org/PathwayBrowser/#/R-XTR-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Xenopus tropicalis 43474 R-XTR-5692754 https://reactome.org/PathwayBrowser/#/R-XTR-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Xenopus tropicalis 43474 R-XTR-5694126 https://reactome.org/PathwayBrowser/#/R-XTR-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Xenopus tropicalis 43474 R-XTR-5694421 https://reactome.org/PathwayBrowser/#/R-XTR-5694421 PP6 dephosphorylates SEC24 IEA Xenopus tropicalis 43474 R-XTR-5694527 https://reactome.org/PathwayBrowser/#/R-XTR-5694527 Loss of SAR1B GTPase IEA Xenopus tropicalis 43474 R-XTR-5696415 https://reactome.org/PathwayBrowser/#/R-XTR-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Xenopus tropicalis 43474 R-XTR-5696839 https://reactome.org/PathwayBrowser/#/R-XTR-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Xenopus tropicalis 43474 R-XTR-6782131 https://reactome.org/PathwayBrowser/#/R-XTR-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Xenopus tropicalis 43474 R-XTR-6786245 https://reactome.org/PathwayBrowser/#/R-XTR-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Xenopus tropicalis 43474 R-XTR-6788295 https://reactome.org/PathwayBrowser/#/R-XTR-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Xenopus tropicalis 43474 R-XTR-6788912 https://reactome.org/PathwayBrowser/#/R-XTR-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Xenopus tropicalis 43474 R-XTR-6792863 https://reactome.org/PathwayBrowser/#/R-XTR-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Xenopus tropicalis 43474 R-XTR-6797630 https://reactome.org/PathwayBrowser/#/R-XTR-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Xenopus tropicalis 43474 R-XTR-6801342 https://reactome.org/PathwayBrowser/#/R-XTR-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Xenopus tropicalis 43474 R-XTR-6801456 https://reactome.org/PathwayBrowser/#/R-XTR-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Xenopus tropicalis 43474 R-XTR-6803545 https://reactome.org/PathwayBrowser/#/R-XTR-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Xenopus tropicalis 43474 R-XTR-6806967 https://reactome.org/PathwayBrowser/#/R-XTR-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Xenopus tropicalis 43474 R-XTR-6807027 https://reactome.org/PathwayBrowser/#/R-XTR-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Xenopus tropicalis 43474 R-XTR-6809015 https://reactome.org/PathwayBrowser/#/R-XTR-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Xenopus tropicalis 43474 R-XTR-6809720 https://reactome.org/PathwayBrowser/#/R-XTR-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Xenopus tropicalis 43474 R-XTR-6810410 https://reactome.org/PathwayBrowser/#/R-XTR-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Xenopus tropicalis 43474 R-XTR-6814120 https://reactome.org/PathwayBrowser/#/R-XTR-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Xenopus tropicalis 43474 R-XTR-69199 https://reactome.org/PathwayBrowser/#/R-XTR-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Xenopus tropicalis 43474 R-XTR-70449 https://reactome.org/PathwayBrowser/#/R-XTR-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Xenopus tropicalis 43474 R-XTR-70479 https://reactome.org/PathwayBrowser/#/R-XTR-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Xenopus tropicalis 43474 R-XTR-70482 https://reactome.org/PathwayBrowser/#/R-XTR-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Xenopus tropicalis 43474 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 43474 R-XTR-70555 https://reactome.org/PathwayBrowser/#/R-XTR-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Xenopus tropicalis 43474 R-XTR-70560 https://reactome.org/PathwayBrowser/#/R-XTR-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Xenopus tropicalis 43474 R-XTR-70606 https://reactome.org/PathwayBrowser/#/R-XTR-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Xenopus tropicalis 43474 R-XTR-70773 https://reactome.org/PathwayBrowser/#/R-XTR-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Xenopus tropicalis 43474 R-XTR-70997 https://reactome.org/PathwayBrowser/#/R-XTR-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Xenopus tropicalis 43474 R-XTR-71031 https://reactome.org/PathwayBrowser/#/R-XTR-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Xenopus tropicalis 43474 R-XTR-71590 https://reactome.org/PathwayBrowser/#/R-XTR-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Xenopus tropicalis 43474 R-XTR-71732 https://reactome.org/PathwayBrowser/#/R-XTR-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Xenopus tropicalis 43474 R-XTR-71775 https://reactome.org/PathwayBrowser/#/R-XTR-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Xenopus tropicalis 43474 R-XTR-71825 https://reactome.org/PathwayBrowser/#/R-XTR-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Xenopus tropicalis 43474 R-XTR-72621 https://reactome.org/PathwayBrowser/#/R-XTR-72621 Ribosomal scanning IEA Xenopus tropicalis 43474 R-XTR-72671 https://reactome.org/PathwayBrowser/#/R-XTR-72671 eIF5B:GTP is hydrolyzed and released IEA Xenopus tropicalis 43474 R-XTR-73573 https://reactome.org/PathwayBrowser/#/R-XTR-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Xenopus tropicalis 43474 R-XTR-73577 https://reactome.org/PathwayBrowser/#/R-XTR-73577 CAD hexamer transforms L-Gln to CAP IEA Xenopus tropicalis 43474 R-XTR-73805 https://reactome.org/PathwayBrowser/#/R-XTR-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Xenopus tropicalis 43474 R-XTR-73810 https://reactome.org/PathwayBrowser/#/R-XTR-73810 FGAM + ATP => AIR + ADP + Pi IEA Xenopus tropicalis 43474 R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 43474 R-XTR-73814 https://reactome.org/PathwayBrowser/#/R-XTR-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Xenopus tropicalis 43474 R-XTR-74242 https://reactome.org/PathwayBrowser/#/R-XTR-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Xenopus tropicalis 43474 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 43474 R-XTR-74249 https://reactome.org/PathwayBrowser/#/R-XTR-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Xenopus tropicalis 43474 R-XTR-74372 https://reactome.org/PathwayBrowser/#/R-XTR-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Xenopus tropicalis 43474 R-XTR-74376 https://reactome.org/PathwayBrowser/#/R-XTR-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Xenopus tropicalis 43474 R-XTR-74733 https://reactome.org/PathwayBrowser/#/R-XTR-74733 Insulin receptor de-phosphorylation IEA Xenopus tropicalis 43474 R-XTR-75848 https://reactome.org/PathwayBrowser/#/R-XTR-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Xenopus tropicalis 43474 R-XTR-75851 https://reactome.org/PathwayBrowser/#/R-XTR-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 43474 R-XTR-75899 https://reactome.org/PathwayBrowser/#/R-XTR-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Xenopus tropicalis 43474 R-XTR-75949 https://reactome.org/PathwayBrowser/#/R-XTR-75949 RNA Polymerase II Promoter Opening: First Transition IEA Xenopus tropicalis 43474 R-XTR-77078 https://reactome.org/PathwayBrowser/#/R-XTR-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Xenopus tropicalis 43474 R-XTR-8848053 https://reactome.org/PathwayBrowser/#/R-XTR-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Xenopus tropicalis 43474 R-XTR-8849082 https://reactome.org/PathwayBrowser/#/R-XTR-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Xenopus tropicalis 43474 R-XTR-8849435 https://reactome.org/PathwayBrowser/#/R-XTR-8849435 PTPN1 dephosphorylates PTK6 IEA Xenopus tropicalis 43474 R-XTR-8849969 https://reactome.org/PathwayBrowser/#/R-XTR-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Xenopus tropicalis 43474 R-XTR-8850846 https://reactome.org/PathwayBrowser/#/R-XTR-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 43474 R-XTR-8850854 https://reactome.org/PathwayBrowser/#/R-XTR-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 43474 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 43474 R-XTR-8851110 https://reactome.org/PathwayBrowser/#/R-XTR-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 43474 R-XTR-8851129 https://reactome.org/PathwayBrowser/#/R-XTR-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 43474 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 43474 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 43474 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 43474 R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 43474 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 43474 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 43474 R-XTR-8854173 https://reactome.org/PathwayBrowser/#/R-XTR-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Xenopus tropicalis 43474 R-XTR-8854255 https://reactome.org/PathwayBrowser/#/R-XTR-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 43474 R-XTR-8854329 https://reactome.org/PathwayBrowser/#/R-XTR-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 43474 R-XTR-8854612 https://reactome.org/PathwayBrowser/#/R-XTR-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Xenopus tropicalis 43474 R-XTR-8864029 https://reactome.org/PathwayBrowser/#/R-XTR-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Xenopus tropicalis 43474 R-XTR-8864036 https://reactome.org/PathwayBrowser/#/R-XTR-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Xenopus tropicalis 43474 R-XTR-8864125 https://reactome.org/PathwayBrowser/#/R-XTR-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Xenopus tropicalis 43474 R-XTR-8865774 https://reactome.org/PathwayBrowser/#/R-XTR-8865774 TTLLs polyglutamylate tubulin IEA Xenopus tropicalis 43474 R-XTR-8866542 https://reactome.org/PathwayBrowser/#/R-XTR-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Xenopus tropicalis 43474 R-XTR-8867370 https://reactome.org/PathwayBrowser/#/R-XTR-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Xenopus tropicalis 43474 R-XTR-8867658 https://reactome.org/PathwayBrowser/#/R-XTR-8867658 PTPN3 dephosphorylates MAPK12 IEA Xenopus tropicalis 43474 R-XTR-8876889 https://reactome.org/PathwayBrowser/#/R-XTR-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 43474 R-XTR-8878654 https://reactome.org/PathwayBrowser/#/R-XTR-8878654 ACP6 hydrolyses MYS-LPA IEA Xenopus tropicalis 43474 R-XTR-8878787 https://reactome.org/PathwayBrowser/#/R-XTR-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Xenopus tropicalis 43474 R-XTR-8937767 https://reactome.org/PathwayBrowser/#/R-XTR-8937767 PTPN11 dephosphorylates RUNX1 IEA Xenopus tropicalis 43474 R-XTR-8940070 https://reactome.org/PathwayBrowser/#/R-XTR-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Xenopus tropicalis 43474 R-XTR-8940074 https://reactome.org/PathwayBrowser/#/R-XTR-8940074 NT5E:Zn2+ hydrolyses NMN IEA Xenopus tropicalis 43474 R-XTR-8951498 https://reactome.org/PathwayBrowser/#/R-XTR-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Xenopus tropicalis 43474 R-XTR-8952137 https://reactome.org/PathwayBrowser/#/R-XTR-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Xenopus tropicalis 43474 R-XTR-8953499 https://reactome.org/PathwayBrowser/#/R-XTR-8953499 IMPAD1 hydrolyses PAP to AMP IEA Xenopus tropicalis 43474 R-XTR-8981637 https://reactome.org/PathwayBrowser/#/R-XTR-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Xenopus tropicalis 43474 R-XTR-8982020 https://reactome.org/PathwayBrowser/#/R-XTR-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Xenopus tropicalis 43474 R-XTR-8982021 https://reactome.org/PathwayBrowser/#/R-XTR-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Xenopus tropicalis 43474 R-XTR-8982025 https://reactome.org/PathwayBrowser/#/R-XTR-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Xenopus tropicalis 43474 R-XTR-8985594 https://reactome.org/PathwayBrowser/#/R-XTR-8985594 MYO9B inactivates RHOA IEA Xenopus tropicalis 43474 R-XTR-9013022 https://reactome.org/PathwayBrowser/#/R-XTR-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Xenopus tropicalis 43474 R-XTR-9013144 https://reactome.org/PathwayBrowser/#/R-XTR-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Xenopus tropicalis 43474 R-XTR-9013161 https://reactome.org/PathwayBrowser/#/R-XTR-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Xenopus tropicalis 43474 R-XTR-9013437 https://reactome.org/PathwayBrowser/#/R-XTR-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Xenopus tropicalis 43474 R-XTR-9014295 https://reactome.org/PathwayBrowser/#/R-XTR-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Xenopus tropicalis 43474 R-XTR-9014434 https://reactome.org/PathwayBrowser/#/R-XTR-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Xenopus tropicalis 43474 R-XTR-9017488 https://reactome.org/PathwayBrowser/#/R-XTR-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Xenopus tropicalis 43474 R-XTR-9018745 https://reactome.org/PathwayBrowser/#/R-XTR-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Xenopus tropicalis 43474 R-XTR-9018806 https://reactome.org/PathwayBrowser/#/R-XTR-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Xenopus tropicalis 43474 R-XTR-9018826 https://reactome.org/PathwayBrowser/#/R-XTR-9018826 RHOT2 hydrolyzes GTP IEA Xenopus tropicalis 43474 R-XTR-917693 https://reactome.org/PathwayBrowser/#/R-XTR-917693 ESCRT Disassembly IEA Xenopus tropicalis 43474 R-XTR-917841 https://reactome.org/PathwayBrowser/#/R-XTR-917841 Acidification of Tf:TfR1 containing endosome IEA Xenopus tropicalis 43474 R-XTR-917979 https://reactome.org/PathwayBrowser/#/R-XTR-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Xenopus tropicalis 43474 R-XTR-936802 https://reactome.org/PathwayBrowser/#/R-XTR-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Xenopus tropicalis 43474 R-XTR-936883 https://reactome.org/PathwayBrowser/#/R-XTR-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Xenopus tropicalis 43474 R-XTR-936895 https://reactome.org/PathwayBrowser/#/R-XTR-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Xenopus tropicalis 43474 R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 43474 R-XTR-937311 https://reactome.org/PathwayBrowser/#/R-XTR-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 43474 R-XTR-939763 https://reactome.org/PathwayBrowser/#/R-XTR-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-947591 https://reactome.org/PathwayBrowser/#/R-XTR-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Xenopus tropicalis 43474 R-XTR-9624893 https://reactome.org/PathwayBrowser/#/R-XTR-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Xenopus tropicalis 43474 R-XTR-9640195 https://reactome.org/PathwayBrowser/#/R-XTR-9640195 RRAGA,B hydrolyzes GTP IEA Xenopus tropicalis 43474 R-XTR-9645598 https://reactome.org/PathwayBrowser/#/R-XTR-9645598 RRAGC,D hydrolyzes GTP IEA Xenopus tropicalis 43474 R-XTR-965067 https://reactome.org/PathwayBrowser/#/R-XTR-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Xenopus tropicalis 43474 R-XTR-9661417 https://reactome.org/PathwayBrowser/#/R-XTR-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 43474 R-XTR-9668419 https://reactome.org/PathwayBrowser/#/R-XTR-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Xenopus tropicalis 43474 R-XTR-9684118 https://reactome.org/PathwayBrowser/#/R-XTR-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Xenopus tropicalis 43474 R-XTR-9686524 https://reactome.org/PathwayBrowser/#/R-XTR-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Xenopus tropicalis 43474 R-XTR-9693282 https://reactome.org/PathwayBrowser/#/R-XTR-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Xenopus tropicalis 43474 R-XTR-9727198 https://reactome.org/PathwayBrowser/#/R-XTR-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 43474 R-XTR-9750617 https://reactome.org/PathwayBrowser/#/R-XTR-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Xenopus tropicalis 43474 R-XTR-9750656 https://reactome.org/PathwayBrowser/#/R-XTR-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Xenopus tropicalis 43474 R-XTR-9753278 https://reactome.org/PathwayBrowser/#/R-XTR-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 43474 R-XTR-9753283 https://reactome.org/PathwayBrowser/#/R-XTR-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 43474 R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 43474 R-XTR-977324 https://reactome.org/PathwayBrowser/#/R-XTR-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Xenopus tropicalis 43474 R-XTR-9838289 https://reactome.org/PathwayBrowser/#/R-XTR-9838289 CLPXP degrades mitochondrial matrix proteins IEA Xenopus tropicalis 43474 R-XTR-9839059 https://reactome.org/PathwayBrowser/#/R-XTR-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Xenopus tropicalis 43474 R-XTR-9839105 https://reactome.org/PathwayBrowser/#/R-XTR-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Xenopus tropicalis 43474 R-XTR-9839113 https://reactome.org/PathwayBrowser/#/R-XTR-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Xenopus tropicalis 43474 R-XTR-9843721 https://reactome.org/PathwayBrowser/#/R-XTR-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Xenopus tropicalis 43474 R-XTR-9853385 https://reactome.org/PathwayBrowser/#/R-XTR-9853385 PPP1CC dephosphorylates PLK1 IEA Xenopus tropicalis 43474 R-XTR-997309 https://reactome.org/PathwayBrowser/#/R-XTR-997309 Dephosphorylation of STAT1 by SHP2 IEA Xenopus tropicalis 43474 R-XTR-997311 https://reactome.org/PathwayBrowser/#/R-XTR-997311 Dephosphorylation of TYK2 by PTP1B IEA Xenopus tropicalis 43580 R-BTA-893596 https://reactome.org/PathwayBrowser/#/R-BTA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Bos taurus 43580 R-CEL-893596 https://reactome.org/PathwayBrowser/#/R-CEL-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Caenorhabditis elegans 43580 R-CFA-893596 https://reactome.org/PathwayBrowser/#/R-CFA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Canis familiaris 43580 R-DDI-893596 https://reactome.org/PathwayBrowser/#/R-DDI-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Dictyostelium discoideum 43580 R-DME-893596 https://reactome.org/PathwayBrowser/#/R-DME-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Drosophila melanogaster 43580 R-DRE-893596 https://reactome.org/PathwayBrowser/#/R-DRE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Danio rerio 43580 R-GGA-893596 https://reactome.org/PathwayBrowser/#/R-GGA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Gallus gallus 43580 R-HSA-893596 https://reactome.org/PathwayBrowser/#/R-HSA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu TAS Homo sapiens 43580 R-MMU-893596 https://reactome.org/PathwayBrowser/#/R-MMU-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Mus musculus 43580 R-RNO-893596 https://reactome.org/PathwayBrowser/#/R-RNO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Rattus norvegicus 43580 R-SCE-893596 https://reactome.org/PathwayBrowser/#/R-SCE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Saccharomyces cerevisiae 43580 R-SPO-893596 https://reactome.org/PathwayBrowser/#/R-SPO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Schizosaccharomyces pombe 43580 R-SSC-893596 https://reactome.org/PathwayBrowser/#/R-SSC-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Sus scrofa 43580 R-XTR-893596 https://reactome.org/PathwayBrowser/#/R-XTR-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Xenopus tropicalis 43755 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 43755 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 43755 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 43755 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 43755 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 43755 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 43755 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 43755 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 43755 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 43755 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 43755 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 43755 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 43755 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 43755 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 43755 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 43755 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 43755 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 43755 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 43755 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 43755 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 43966 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 43966 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 43966 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 43966 R-BTA-9015379 https://reactome.org/PathwayBrowser/#/R-BTA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Bos taurus 43966 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 43966 R-CFA-9015379 https://reactome.org/PathwayBrowser/#/R-CFA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Canis familiaris 43966 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 43966 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 43966 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 43966 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 43966 R-GGA-9015379 https://reactome.org/PathwayBrowser/#/R-GGA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Gallus gallus 43966 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 43966 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 43966 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 43966 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 43966 R-HSA-9015379 https://reactome.org/PathwayBrowser/#/R-HSA-9015379 Factor IIa inhibitors (compounds) binds IIa TAS Homo sapiens 43966 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 43966 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 43966 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 43966 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 43966 R-MMU-9015379 https://reactome.org/PathwayBrowser/#/R-MMU-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Mus musculus 43966 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 43966 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 43966 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 43966 R-RNO-9015379 https://reactome.org/PathwayBrowser/#/R-RNO-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Rattus norvegicus 43966 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 43966 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 43966 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 43966 R-SSC-9015379 https://reactome.org/PathwayBrowser/#/R-SSC-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Sus scrofa 43966 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 43966 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 43966 R-XTR-9015379 https://reactome.org/PathwayBrowser/#/R-XTR-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Xenopus tropicalis 44074 R-BTA-3204311 https://reactome.org/PathwayBrowser/#/R-BTA-3204311 AOX1 oxidises PXL to PDXate IEA Bos taurus 44074 R-BTA-74247 https://reactome.org/PathwayBrowser/#/R-BTA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Bos taurus 44074 R-BTA-74258 https://reactome.org/PathwayBrowser/#/R-BTA-74258 XDH oxidizes xanthine to form urate IEA Bos taurus 44074 R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 44074 R-BTA-9727349 https://reactome.org/PathwayBrowser/#/R-BTA-9727349 XDH dehydrogenates xanthine to form urate IEA Bos taurus 44074 R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 44074 R-CEL-3204311 https://reactome.org/PathwayBrowser/#/R-CEL-3204311 AOX1 oxidises PXL to PDXate IEA Caenorhabditis elegans 44074 R-CEL-74247 https://reactome.org/PathwayBrowser/#/R-CEL-74247 XDH oxidizes hypoxanthine to form xanthine IEA Caenorhabditis elegans 44074 R-CEL-74258 https://reactome.org/PathwayBrowser/#/R-CEL-74258 XDH oxidizes xanthine to form urate IEA Caenorhabditis elegans 44074 R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 44074 R-CEL-9727349 https://reactome.org/PathwayBrowser/#/R-CEL-9727349 XDH dehydrogenates xanthine to form urate IEA Caenorhabditis elegans 44074 R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 44074 R-CFA-74247 https://reactome.org/PathwayBrowser/#/R-CFA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Canis familiaris 44074 R-CFA-74258 https://reactome.org/PathwayBrowser/#/R-CFA-74258 XDH oxidizes xanthine to form urate IEA Canis familiaris 44074 R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 44074 R-CFA-9727349 https://reactome.org/PathwayBrowser/#/R-CFA-9727349 XDH dehydrogenates xanthine to form urate IEA Canis familiaris 44074 R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 44074 R-DDI-3204311 https://reactome.org/PathwayBrowser/#/R-DDI-3204311 AOX1 oxidises PXL to PDXate IEA Dictyostelium discoideum 44074 R-DDI-74247 https://reactome.org/PathwayBrowser/#/R-DDI-74247 XDH oxidizes hypoxanthine to form xanthine IEA Dictyostelium discoideum 44074 R-DDI-74258 https://reactome.org/PathwayBrowser/#/R-DDI-74258 XDH oxidizes xanthine to form urate IEA Dictyostelium discoideum 44074 R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 44074 R-DDI-9727349 https://reactome.org/PathwayBrowser/#/R-DDI-9727349 XDH dehydrogenates xanthine to form urate IEA Dictyostelium discoideum 44074 R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 44074 R-DME-3204311 https://reactome.org/PathwayBrowser/#/R-DME-3204311 AOX1 oxidises PXL to PDXate IEA Drosophila melanogaster 44074 R-DME-74247 https://reactome.org/PathwayBrowser/#/R-DME-74247 XDH oxidizes hypoxanthine to form xanthine IEA Drosophila melanogaster 44074 R-DME-74258 https://reactome.org/PathwayBrowser/#/R-DME-74258 XDH oxidizes xanthine to form urate IEA Drosophila melanogaster 44074 R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 44074 R-DME-9727349 https://reactome.org/PathwayBrowser/#/R-DME-9727349 XDH dehydrogenates xanthine to form urate IEA Drosophila melanogaster 44074 R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 44074 R-DRE-3204311 https://reactome.org/PathwayBrowser/#/R-DRE-3204311 AOX1 oxidises PXL to PDXate IEA Danio rerio 44074 R-GGA-3204311 https://reactome.org/PathwayBrowser/#/R-GGA-3204311 AOX1 oxidises PXL to PDXate IEA Gallus gallus 44074 R-GGA-74247 https://reactome.org/PathwayBrowser/#/R-GGA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Gallus gallus 44074 R-GGA-74258 https://reactome.org/PathwayBrowser/#/R-GGA-74258 XDH oxidizes xanthine to form urate IEA Gallus gallus 44074 R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 44074 R-GGA-9727349 https://reactome.org/PathwayBrowser/#/R-GGA-9727349 XDH dehydrogenates xanthine to form urate IEA Gallus gallus 44074 R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 44074 R-HSA-3204311 https://reactome.org/PathwayBrowser/#/R-HSA-3204311 AOX1 oxidises PXL to PDXate TAS Homo sapiens 44074 R-HSA-74247 https://reactome.org/PathwayBrowser/#/R-HSA-74247 XDH oxidizes hypoxanthine to form xanthine TAS Homo sapiens 44074 R-HSA-74258 https://reactome.org/PathwayBrowser/#/R-HSA-74258 XDH oxidizes xanthine to form urate TAS Homo sapiens 44074 R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 44074 R-HSA-9727349 https://reactome.org/PathwayBrowser/#/R-HSA-9727349 XDH dehydrogenates xanthine to form urate TAS Homo sapiens 44074 R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 44074 R-MMU-3204311 https://reactome.org/PathwayBrowser/#/R-MMU-3204311 AOX1 oxidises PXL to PDXate IEA Mus musculus 44074 R-MMU-74247 https://reactome.org/PathwayBrowser/#/R-MMU-74247 XDH oxidizes hypoxanthine to form xanthine IEA Mus musculus 44074 R-MMU-74258 https://reactome.org/PathwayBrowser/#/R-MMU-74258 XDH oxidizes xanthine to form urate IEA Mus musculus 44074 R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 44074 R-MMU-9727349 https://reactome.org/PathwayBrowser/#/R-MMU-9727349 XDH dehydrogenates xanthine to form urate IEA Mus musculus 44074 R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 44074 R-RNO-3204311 https://reactome.org/PathwayBrowser/#/R-RNO-3204311 AOX1 oxidises PXL to PDXate IEA Rattus norvegicus 44074 R-RNO-74247 https://reactome.org/PathwayBrowser/#/R-RNO-74247 XDH oxidizes hypoxanthine to form xanthine IEA Rattus norvegicus 44074 R-RNO-74258 https://reactome.org/PathwayBrowser/#/R-RNO-74258 XDH oxidizes xanthine to form urate IEA Rattus norvegicus 44074 R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 44074 R-RNO-9727349 https://reactome.org/PathwayBrowser/#/R-RNO-9727349 XDH dehydrogenates xanthine to form urate IEA Rattus norvegicus 44074 R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 44074 R-SSC-3204311 https://reactome.org/PathwayBrowser/#/R-SSC-3204311 AOX1 oxidises PXL to PDXate IEA Sus scrofa 44074 R-SSC-74247 https://reactome.org/PathwayBrowser/#/R-SSC-74247 XDH oxidizes hypoxanthine to form xanthine IEA Sus scrofa 44074 R-SSC-74258 https://reactome.org/PathwayBrowser/#/R-SSC-74258 XDH oxidizes xanthine to form urate IEA Sus scrofa 44074 R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 44074 R-SSC-9727349 https://reactome.org/PathwayBrowser/#/R-SSC-9727349 XDH dehydrogenates xanthine to form urate IEA Sus scrofa 44074 R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 44074 R-XTR-3204311 https://reactome.org/PathwayBrowser/#/R-XTR-3204311 AOX1 oxidises PXL to PDXate IEA Xenopus tropicalis 44074 R-XTR-74247 https://reactome.org/PathwayBrowser/#/R-XTR-74247 XDH oxidizes hypoxanthine to form xanthine IEA Xenopus tropicalis 44074 R-XTR-74258 https://reactome.org/PathwayBrowser/#/R-XTR-74258 XDH oxidizes xanthine to form urate IEA Xenopus tropicalis 44074 R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 44074 R-XTR-9727349 https://reactome.org/PathwayBrowser/#/R-XTR-9727349 XDH dehydrogenates xanthine to form urate IEA Xenopus tropicalis 44074 R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 44348 R-MTU-879273 https://reactome.org/PathwayBrowser/#/R-MTU-879273 mycothiol conjugates with electrophilic xenobiotic TAS Mycobacterium tuberculosis 44369 R-HSA-9683663 https://reactome.org/PathwayBrowser/#/R-HSA-9683663 N-glycan trimming of Spike TAS Homo sapiens 44369 R-HSA-9686790 https://reactome.org/PathwayBrowser/#/R-HSA-9686790 ER-alpha glucosidases bind ER-alpha glucosidase inhibitors TAS Homo sapiens 44369 R-HSA-9694364 https://reactome.org/PathwayBrowser/#/R-HSA-9694364 N-glycan glucose trimming of Spike TAS Homo sapiens 44605 R-BTA-110243 https://reactome.org/PathwayBrowser/#/R-BTA-110243 Excision of 8-oxoguanine by OGG1 glycosylase IEA Bos taurus 44605 R-CFA-110243 https://reactome.org/PathwayBrowser/#/R-CFA-110243 Excision of 8-oxoguanine by OGG1 glycosylase IEA Canis familiaris 44605 R-DDI-110243 https://reactome.org/PathwayBrowser/#/R-DDI-110243 Excision of 8-oxoguanine by OGG1 glycosylase IEA Dictyostelium discoideum 44605 R-DME-110243 https://reactome.org/PathwayBrowser/#/R-DME-110243 Excision of 8-oxoguanine by OGG1 glycosylase IEA Drosophila melanogaster 44605 R-HSA-110243 https://reactome.org/PathwayBrowser/#/R-HSA-110243 Excision of 8-oxoguanine by OGG1 glycosylase TAS Homo sapiens 44605 R-MMU-110243 https://reactome.org/PathwayBrowser/#/R-MMU-110243 Excision of 8-oxoguanine by OGG1 glycosylase IEA Mus musculus 44605 R-PFA-110243 https://reactome.org/PathwayBrowser/#/R-PFA-110243 Excision of 8-oxoguanine by OGG1 glycosylase IEA Plasmodium falciparum 44605 R-RNO-110243 https://reactome.org/PathwayBrowser/#/R-RNO-110243 Excision of 8-oxoguanine by OGG1 glycosylase IEA Rattus norvegicus 44605 R-SCE-110243 https://reactome.org/PathwayBrowser/#/R-SCE-110243 Excision of 8-oxoguanine by OGG1 glycosylase IEA Saccharomyces cerevisiae 4466 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 4466 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 4466 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 4466 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 4466 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 4466 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 4466 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 4466 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 4466 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 4466 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 4466 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 4470 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 4470 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 4470 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 4470 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 4470 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 4470 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 4470 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 4470 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 4470 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 4470 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 4470 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 4470 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 4470 R-HSA-9679816 https://reactome.org/PathwayBrowser/#/R-HSA-9679816 SIGMAR1 binds dextromethorphan TAS Homo sapiens 4470 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 4470 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 4470 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 4470 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 4470 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 4470 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 4470 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 4470 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 4470 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 4470 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 4495 R-NUL-421961 https://reactome.org/PathwayBrowser/#/R-NUL-421961 Dissociation of beta-2 adrenergic receptor:Gs complex TAS Oryctolagus cuniculus 44975 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 44975 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 44975 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 44975 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 44975 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 44975 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 44975 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 44975 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 44975 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 44975 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 45021 R-BTA-2404137 https://reactome.org/PathwayBrowser/#/R-BTA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 45021 R-BTA-2453855 https://reactome.org/PathwayBrowser/#/R-BTA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 45021 R-BTA-975608 https://reactome.org/PathwayBrowser/#/R-BTA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Bos taurus 45021 R-CFA-2404137 https://reactome.org/PathwayBrowser/#/R-CFA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 45021 R-CFA-2453855 https://reactome.org/PathwayBrowser/#/R-CFA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 45021 R-CFA-975608 https://reactome.org/PathwayBrowser/#/R-CFA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Canis familiaris 45021 R-DRE-2404137 https://reactome.org/PathwayBrowser/#/R-DRE-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 45021 R-DRE-2453855 https://reactome.org/PathwayBrowser/#/R-DRE-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 45021 R-DRE-975608 https://reactome.org/PathwayBrowser/#/R-DRE-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Danio rerio 45021 R-GGA-2404137 https://reactome.org/PathwayBrowser/#/R-GGA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 45021 R-GGA-2453855 https://reactome.org/PathwayBrowser/#/R-GGA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 45021 R-GGA-975608 https://reactome.org/PathwayBrowser/#/R-GGA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Gallus gallus 45021 R-HSA-2404137 https://reactome.org/PathwayBrowser/#/R-HSA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 45021 R-HSA-2453855 https://reactome.org/PathwayBrowser/#/R-HSA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 45021 R-HSA-2466710 https://reactome.org/PathwayBrowser/#/R-HSA-2466710 Defective LRAT does not esterify RBP1:atROL and FACYLs to atREs TAS Homo sapiens 45021 R-HSA-975608 https://reactome.org/PathwayBrowser/#/R-HSA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs TAS Homo sapiens 45021 R-MMU-2404137 https://reactome.org/PathwayBrowser/#/R-MMU-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 45021 R-MMU-2453855 https://reactome.org/PathwayBrowser/#/R-MMU-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 45021 R-MMU-975608 https://reactome.org/PathwayBrowser/#/R-MMU-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Mus musculus 45021 R-RNO-2404137 https://reactome.org/PathwayBrowser/#/R-RNO-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 45021 R-RNO-2453855 https://reactome.org/PathwayBrowser/#/R-RNO-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 45021 R-RNO-975608 https://reactome.org/PathwayBrowser/#/R-RNO-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Rattus norvegicus 45021 R-SSC-2404137 https://reactome.org/PathwayBrowser/#/R-SSC-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 45021 R-SSC-2453855 https://reactome.org/PathwayBrowser/#/R-SSC-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 45021 R-SSC-975608 https://reactome.org/PathwayBrowser/#/R-SSC-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Sus scrofa 45021 R-XTR-2404137 https://reactome.org/PathwayBrowser/#/R-XTR-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 45021 R-XTR-2453855 https://reactome.org/PathwayBrowser/#/R-XTR-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 45021 R-XTR-975608 https://reactome.org/PathwayBrowser/#/R-XTR-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Xenopus tropicalis 4513 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 4513 R-BTA-9026967 https://reactome.org/PathwayBrowser/#/R-BTA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Bos taurus 4513 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 4513 R-CFA-9026967 https://reactome.org/PathwayBrowser/#/R-CFA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Canis familiaris 4513 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 4513 R-DME-9026967 https://reactome.org/PathwayBrowser/#/R-DME-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Drosophila melanogaster 4513 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 4513 R-HSA-9026967 https://reactome.org/PathwayBrowser/#/R-HSA-9026967 VKORC1 inhibitors binds VKORC1 dimer TAS Homo sapiens 4513 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 4513 R-MMU-9026967 https://reactome.org/PathwayBrowser/#/R-MMU-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Mus musculus 4513 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 4513 R-RNO-9026967 https://reactome.org/PathwayBrowser/#/R-RNO-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Rattus norvegicus 4513 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 4513 R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa 4513 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 4513 R-XTR-9026967 https://reactome.org/PathwayBrowser/#/R-XTR-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Xenopus tropicalis 45360 R-HSA-1483212 https://reactome.org/PathwayBrowser/#/R-HSA-1483212 PS is decarboxylated to PE by PISD IEA Homo sapiens 45360 R-RNO-1483118 https://reactome.org/PathwayBrowser/#/R-RNO-1483118 PS is decarboxylated to PE by Pisd TAS Rattus norvegicus 45373 R-BTA-174963 https://reactome.org/PathwayBrowser/#/R-BTA-174963 NAT1 acetylation IEA Bos taurus 45373 R-DRE-174963 https://reactome.org/PathwayBrowser/#/R-DRE-174963 NAT1 acetylation IEA Danio rerio 45373 R-GGA-174963 https://reactome.org/PathwayBrowser/#/R-GGA-174963 NAT1 acetylation IEA Gallus gallus 45373 R-HSA-174963 https://reactome.org/PathwayBrowser/#/R-HSA-174963 NAT1 acetylation TAS Homo sapiens 45373 R-MMU-174963 https://reactome.org/PathwayBrowser/#/R-MMU-174963 NAT1 acetylation IEA Mus musculus 45373 R-RNO-174963 https://reactome.org/PathwayBrowser/#/R-RNO-174963 NAT1 acetylation IEA Rattus norvegicus 45373 R-SSC-174963 https://reactome.org/PathwayBrowser/#/R-SSC-174963 NAT1 acetylation IEA Sus scrofa 4551 R-BTA-879594 https://reactome.org/PathwayBrowser/#/R-BTA-879594 SLCO4C1 mediates the transport of digoxin IEA Bos taurus 4551 R-CEL-879594 https://reactome.org/PathwayBrowser/#/R-CEL-879594 SLCO4C1 mediates the transport of digoxin IEA Caenorhabditis elegans 4551 R-CFA-879594 https://reactome.org/PathwayBrowser/#/R-CFA-879594 SLCO4C1 mediates the transport of digoxin IEA Canis familiaris 4551 R-DME-879594 https://reactome.org/PathwayBrowser/#/R-DME-879594 SLCO4C1 mediates the transport of digoxin IEA Drosophila melanogaster 4551 R-GGA-879594 https://reactome.org/PathwayBrowser/#/R-GGA-879594 SLCO4C1 mediates the transport of digoxin IEA Gallus gallus 4551 R-HSA-879594 https://reactome.org/PathwayBrowser/#/R-HSA-879594 SLCO4C1 mediates the transport of digoxin TAS Homo sapiens 4551 R-MMU-879594 https://reactome.org/PathwayBrowser/#/R-MMU-879594 SLCO4C1 mediates the transport of digoxin IEA Mus musculus 4551 R-RNO-879594 https://reactome.org/PathwayBrowser/#/R-RNO-879594 SLCO4C1 mediates the transport of digoxin IEA Rattus norvegicus 4551 R-SSC-879594 https://reactome.org/PathwayBrowser/#/R-SSC-879594 SLCO4C1 mediates the transport of digoxin IEA Sus scrofa 4551 R-XTR-879594 https://reactome.org/PathwayBrowser/#/R-XTR-879594 SLCO4C1 mediates the transport of digoxin IEA Xenopus tropicalis 45563 R-MTU-879281 https://reactome.org/PathwayBrowser/#/R-MTU-879281 mycothiol is cleaved to acetylcysteine and glucosaminylinositol TAS Mycobacterium tuberculosis 45571 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 45571 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 45571 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 45571 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 45571 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 45571 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 45571 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 45571 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 45571 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 456215 R-BTA-1008248 https://reactome.org/PathwayBrowser/#/R-BTA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Bos taurus 456215 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 456215 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 456215 R-BTA-109415 https://reactome.org/PathwayBrowser/#/R-BTA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Bos taurus 456215 R-BTA-109624 https://reactome.org/PathwayBrowser/#/R-BTA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Bos taurus 456215 R-BTA-110137 https://reactome.org/PathwayBrowser/#/R-BTA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Bos taurus 456215 R-BTA-110138 https://reactome.org/PathwayBrowser/#/R-BTA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 456215 R-BTA-110141 https://reactome.org/PathwayBrowser/#/R-BTA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Bos taurus 456215 R-BTA-110144 https://reactome.org/PathwayBrowser/#/R-BTA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Bos taurus 456215 R-BTA-110145 https://reactome.org/PathwayBrowser/#/R-BTA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Bos taurus 456215 R-BTA-111285 https://reactome.org/PathwayBrowser/#/R-BTA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Bos taurus 456215 R-BTA-111955 https://reactome.org/PathwayBrowser/#/R-BTA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Bos taurus 456215 R-BTA-111962 https://reactome.org/PathwayBrowser/#/R-BTA-111962 PDE4A,C,D hydrolyse cAMP IEA Bos taurus 456215 R-BTA-1169394 https://reactome.org/PathwayBrowser/#/R-BTA-1169394 ISGylation of IRF3 IEA Bos taurus 456215 R-BTA-1169397 https://reactome.org/PathwayBrowser/#/R-BTA-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Bos taurus 456215 R-BTA-1169398 https://reactome.org/PathwayBrowser/#/R-BTA-1169398 ISGylation of host protein filamin B IEA Bos taurus 456215 R-BTA-1169402 https://reactome.org/PathwayBrowser/#/R-BTA-1169402 ISGylation of E2 conjugating enzymes IEA Bos taurus 456215 R-BTA-1169405 https://reactome.org/PathwayBrowser/#/R-BTA-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Bos taurus 456215 R-BTA-1169406 https://reactome.org/PathwayBrowser/#/R-BTA-1169406 ISGylation of host proteins IEA Bos taurus 456215 R-BTA-159425 https://reactome.org/PathwayBrowser/#/R-BTA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 456215 R-BTA-159443 https://reactome.org/PathwayBrowser/#/R-BTA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Bos taurus 456215 R-BTA-159567 https://reactome.org/PathwayBrowser/#/R-BTA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Bos taurus 456215 R-BTA-162425 https://reactome.org/PathwayBrowser/#/R-BTA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Bos taurus 456215 R-BTA-1632857 https://reactome.org/PathwayBrowser/#/R-BTA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Bos taurus 456215 R-BTA-163664 https://reactome.org/PathwayBrowser/#/R-BTA-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Bos taurus 456215 R-BTA-174441 https://reactome.org/PathwayBrowser/#/R-BTA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Bos taurus 456215 R-BTA-176606 https://reactome.org/PathwayBrowser/#/R-BTA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Bos taurus 456215 R-BTA-177157 https://reactome.org/PathwayBrowser/#/R-BTA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Bos taurus 456215 R-BTA-192137 https://reactome.org/PathwayBrowser/#/R-BTA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 456215 R-BTA-193401 https://reactome.org/PathwayBrowser/#/R-BTA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 456215 R-BTA-193407 https://reactome.org/PathwayBrowser/#/R-BTA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 456215 R-BTA-193424 https://reactome.org/PathwayBrowser/#/R-BTA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 456215 R-BTA-193711 https://reactome.org/PathwayBrowser/#/R-BTA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 456215 R-BTA-193727 https://reactome.org/PathwayBrowser/#/R-BTA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 456215 R-BTA-193743 https://reactome.org/PathwayBrowser/#/R-BTA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 456215 R-BTA-193766 https://reactome.org/PathwayBrowser/#/R-BTA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 456215 R-BTA-196753 https://reactome.org/PathwayBrowser/#/R-BTA-196753 2xPPCS ligates PPanK with Cys IEA Bos taurus 456215 R-BTA-196761 https://reactome.org/PathwayBrowser/#/R-BTA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Bos taurus 456215 R-BTA-196955 https://reactome.org/PathwayBrowser/#/R-BTA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Bos taurus 456215 R-BTA-197271 https://reactome.org/PathwayBrowser/#/R-BTA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Bos taurus 456215 R-BTA-200421 https://reactome.org/PathwayBrowser/#/R-BTA-200421 Activation of cytosolic AMPK by phosphorylation IEA Bos taurus 456215 R-BTA-201035 https://reactome.org/PathwayBrowser/#/R-BTA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Bos taurus 456215 R-BTA-2046085 https://reactome.org/PathwayBrowser/#/R-BTA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Bos taurus 456215 R-BTA-2046098 https://reactome.org/PathwayBrowser/#/R-BTA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Bos taurus 456215 R-BTA-2393939 https://reactome.org/PathwayBrowser/#/R-BTA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 456215 R-BTA-2393954 https://reactome.org/PathwayBrowser/#/R-BTA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 456215 R-BTA-2990833 https://reactome.org/PathwayBrowser/#/R-BTA-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Bos taurus 456215 R-BTA-2993447 https://reactome.org/PathwayBrowser/#/R-BTA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Bos taurus 456215 R-BTA-2993799 https://reactome.org/PathwayBrowser/#/R-BTA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Bos taurus 456215 R-BTA-2993802 https://reactome.org/PathwayBrowser/#/R-BTA-2993802 HLCS biotinylates PC:Mn2+ IEA Bos taurus 456215 R-BTA-2993814 https://reactome.org/PathwayBrowser/#/R-BTA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Bos taurus 456215 R-BTA-380927 https://reactome.org/PathwayBrowser/#/R-BTA-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Bos taurus 456215 R-BTA-380930 https://reactome.org/PathwayBrowser/#/R-BTA-380930 Phosphorylated AMPK binds AMP IEA Bos taurus 456215 R-BTA-389622 https://reactome.org/PathwayBrowser/#/R-BTA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 456215 R-BTA-389632 https://reactome.org/PathwayBrowser/#/R-BTA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 456215 R-BTA-389652 https://reactome.org/PathwayBrowser/#/R-BTA-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Bos taurus 456215 R-BTA-4167511 https://reactome.org/PathwayBrowser/#/R-BTA-4167511 HLCS biotinylates ACACB IEA Bos taurus 456215 R-BTA-418553 https://reactome.org/PathwayBrowser/#/R-BTA-418553 cAMP degradation by Phosphodiesterases IEA Bos taurus 456215 R-BTA-429955 https://reactome.org/PathwayBrowser/#/R-BTA-429955 CCR4-NOT complex deadenylates mRNA IEA Bos taurus 456215 R-BTA-429992 https://reactome.org/PathwayBrowser/#/R-BTA-429992 PARN deadenylates mRNA IEA Bos taurus 456215 R-BTA-430021 https://reactome.org/PathwayBrowser/#/R-BTA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Bos taurus 456215 R-BTA-430028 https://reactome.org/PathwayBrowser/#/R-BTA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Bos taurus 456215 R-BTA-434382 https://reactome.org/PathwayBrowser/#/R-BTA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Bos taurus 456215 R-BTA-447074 https://reactome.org/PathwayBrowser/#/R-BTA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Bos taurus 456215 R-BTA-449911 https://reactome.org/PathwayBrowser/#/R-BTA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Bos taurus 456215 R-BTA-453338 https://reactome.org/PathwayBrowser/#/R-BTA-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP IEA Bos taurus 456215 R-BTA-453342 https://reactome.org/PathwayBrowser/#/R-BTA-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Bos taurus 456215 R-BTA-5358475 https://reactome.org/PathwayBrowser/#/R-BTA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Bos taurus 456215 R-BTA-5358592 https://reactome.org/PathwayBrowser/#/R-BTA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Bos taurus 456215 R-BTA-548843 https://reactome.org/PathwayBrowser/#/R-BTA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Bos taurus 456215 R-BTA-5631941 https://reactome.org/PathwayBrowser/#/R-BTA-5631941 SESN1,2,3 bind AMPK IEA Bos taurus 456215 R-BTA-5665868 https://reactome.org/PathwayBrowser/#/R-BTA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Bos taurus 456215 R-BTA-5672008 https://reactome.org/PathwayBrowser/#/R-BTA-5672008 Thr-180 of ULK1 is phosphorylated IEA Bos taurus 456215 R-BTA-5672011 https://reactome.org/PathwayBrowser/#/R-BTA-5672011 p-AMPK:AMP binds the ULK complex IEA Bos taurus 456215 R-BTA-5673768 https://reactome.org/PathwayBrowser/#/R-BTA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Bos taurus 456215 R-BTA-5675868 https://reactome.org/PathwayBrowser/#/R-BTA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Bos taurus 456215 R-BTA-5679205 https://reactome.org/PathwayBrowser/#/R-BTA-5679205 ULK1 phosphorylates Beclin-1 IEA Bos taurus 456215 R-BTA-5679239 https://reactome.org/PathwayBrowser/#/R-BTA-5679239 ULK complex translocates to the ER IEA Bos taurus 456215 R-BTA-5694494 https://reactome.org/PathwayBrowser/#/R-BTA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Bos taurus 456215 R-BTA-5696004 https://reactome.org/PathwayBrowser/#/R-BTA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Bos taurus 456215 R-BTA-5696007 https://reactome.org/PathwayBrowser/#/R-BTA-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Bos taurus 456215 R-BTA-5696021 https://reactome.org/PathwayBrowser/#/R-BTA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Bos taurus 456215 R-BTA-5696049 https://reactome.org/PathwayBrowser/#/R-BTA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 456215 R-BTA-6788798 https://reactome.org/PathwayBrowser/#/R-BTA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 456215 R-BTA-6788810 https://reactome.org/PathwayBrowser/#/R-BTA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 456215 R-BTA-6805470 https://reactome.org/PathwayBrowser/#/R-BTA-6805470 AMPK phosphorylates TP53 IEA Bos taurus 456215 R-BTA-6809287 https://reactome.org/PathwayBrowser/#/R-BTA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Bos taurus 456215 R-BTA-69144 https://reactome.org/PathwayBrowser/#/R-BTA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Bos taurus 456215 R-BTA-70467 https://reactome.org/PathwayBrowser/#/R-BTA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Bos taurus 456215 R-BTA-70479 https://reactome.org/PathwayBrowser/#/R-BTA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Bos taurus 456215 R-BTA-70577 https://reactome.org/PathwayBrowser/#/R-BTA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Bos taurus 456215 R-BTA-70599 https://reactome.org/PathwayBrowser/#/R-BTA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Bos taurus 456215 R-BTA-71735 https://reactome.org/PathwayBrowser/#/R-BTA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Bos taurus 456215 R-BTA-73580 https://reactome.org/PathwayBrowser/#/R-BTA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Bos taurus 456215 R-BTA-73792 https://reactome.org/PathwayBrowser/#/R-BTA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Bos taurus 456215 R-BTA-73828 https://reactome.org/PathwayBrowser/#/R-BTA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Bos taurus 456215 R-BTA-74213 https://reactome.org/PathwayBrowser/#/R-BTA-74213 APRT catalyzes the conversion of adenine to AMP IEA Bos taurus 456215 R-BTA-74220 https://reactome.org/PathwayBrowser/#/R-BTA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Bos taurus 456215 R-BTA-76590 https://reactome.org/PathwayBrowser/#/R-BTA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Bos taurus 456215 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 456215 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 456215 R-BTA-8852133 https://reactome.org/PathwayBrowser/#/R-BTA-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Bos taurus 456215 R-BTA-8852136 https://reactome.org/PathwayBrowser/#/R-BTA-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Bos taurus 456215 R-BTA-8875071 https://reactome.org/PathwayBrowser/#/R-BTA-8875071 ACSS3 ligates CoA to CH3COO- IEA Bos taurus 456215 R-BTA-8951648 https://reactome.org/PathwayBrowser/#/R-BTA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Bos taurus 456215 R-BTA-8951656 https://reactome.org/PathwayBrowser/#/R-BTA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Bos taurus 456215 R-BTA-8953499 https://reactome.org/PathwayBrowser/#/R-BTA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Bos taurus 456215 R-BTA-9009950 https://reactome.org/PathwayBrowser/#/R-BTA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Bos taurus 456215 R-BTA-947531 https://reactome.org/PathwayBrowser/#/R-BTA-947531 Molybdenum ion transfer onto molybdopterin IEA Bos taurus 456215 R-BTA-9613494 https://reactome.org/PathwayBrowser/#/R-BTA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Bos taurus 456215 R-BTA-9629675 https://reactome.org/PathwayBrowser/#/R-BTA-9629675 PDE3A hydrolyses cAMP to AMP IEA Bos taurus 456215 R-BTA-9644869 https://reactome.org/PathwayBrowser/#/R-BTA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Bos taurus 456215 R-BTA-9705507 https://reactome.org/PathwayBrowser/#/R-BTA-9705507 PDE3B hydrolyses cAMP to AMP IEA Bos taurus 456215 R-BTA-9708261 https://reactome.org/PathwayBrowser/#/R-BTA-9708261 PDE4A hydrolyses cAMP to AMP IEA Bos taurus 456215 R-BTA-9734535 https://reactome.org/PathwayBrowser/#/R-BTA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Bos taurus 456215 R-BTA-9748957 https://reactome.org/PathwayBrowser/#/R-BTA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Bos taurus 456215 R-BTA-9749971 https://reactome.org/PathwayBrowser/#/R-BTA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Bos taurus 456215 R-BTA-983140 https://reactome.org/PathwayBrowser/#/R-BTA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Bos taurus 456215 R-BTA-983153 https://reactome.org/PathwayBrowser/#/R-BTA-983153 E1 mediated ubiquitin activation IEA Bos taurus 456215 R-BTA-983156 https://reactome.org/PathwayBrowser/#/R-BTA-983156 Polyubiquitination of substrate IEA Bos taurus 456215 R-BTA-9833973 https://reactome.org/PathwayBrowser/#/R-BTA-9833973 ISGylation of PKR IEA Bos taurus 456215 R-CEL-109624 https://reactome.org/PathwayBrowser/#/R-CEL-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Caenorhabditis elegans 456215 R-CEL-110137 https://reactome.org/PathwayBrowser/#/R-CEL-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Caenorhabditis elegans 456215 R-CEL-110138 https://reactome.org/PathwayBrowser/#/R-CEL-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 456215 R-CEL-110141 https://reactome.org/PathwayBrowser/#/R-CEL-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Caenorhabditis elegans 456215 R-CEL-110144 https://reactome.org/PathwayBrowser/#/R-CEL-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Caenorhabditis elegans 456215 R-CEL-110145 https://reactome.org/PathwayBrowser/#/R-CEL-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Caenorhabditis elegans 456215 R-CEL-111285 https://reactome.org/PathwayBrowser/#/R-CEL-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Caenorhabditis elegans 456215 R-CEL-111955 https://reactome.org/PathwayBrowser/#/R-CEL-111955 cAMP hydrolysis by Cam-PDE 1 IEA Caenorhabditis elegans 456215 R-CEL-111962 https://reactome.org/PathwayBrowser/#/R-CEL-111962 PDE4A,C,D hydrolyse cAMP IEA Caenorhabditis elegans 456215 R-CEL-1169397 https://reactome.org/PathwayBrowser/#/R-CEL-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Caenorhabditis elegans 456215 R-CEL-1169398 https://reactome.org/PathwayBrowser/#/R-CEL-1169398 ISGylation of host protein filamin B IEA Caenorhabditis elegans 456215 R-CEL-1169402 https://reactome.org/PathwayBrowser/#/R-CEL-1169402 ISGylation of E2 conjugating enzymes IEA Caenorhabditis elegans 456215 R-CEL-1169405 https://reactome.org/PathwayBrowser/#/R-CEL-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Caenorhabditis elegans 456215 R-CEL-1169406 https://reactome.org/PathwayBrowser/#/R-CEL-1169406 ISGylation of host proteins IEA Caenorhabditis elegans 456215 R-CEL-159425 https://reactome.org/PathwayBrowser/#/R-CEL-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 456215 R-CEL-162425 https://reactome.org/PathwayBrowser/#/R-CEL-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Caenorhabditis elegans 456215 R-CEL-1632857 https://reactome.org/PathwayBrowser/#/R-CEL-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Caenorhabditis elegans 456215 R-CEL-163664 https://reactome.org/PathwayBrowser/#/R-CEL-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Caenorhabditis elegans 456215 R-CEL-169260 https://reactome.org/PathwayBrowser/#/R-CEL-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Caenorhabditis elegans 456215 R-CEL-169270 https://reactome.org/PathwayBrowser/#/R-CEL-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Caenorhabditis elegans 456215 R-CEL-176606 https://reactome.org/PathwayBrowser/#/R-CEL-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Caenorhabditis elegans 456215 R-CEL-192137 https://reactome.org/PathwayBrowser/#/R-CEL-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 456215 R-CEL-193401 https://reactome.org/PathwayBrowser/#/R-CEL-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 456215 R-CEL-193407 https://reactome.org/PathwayBrowser/#/R-CEL-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 456215 R-CEL-193424 https://reactome.org/PathwayBrowser/#/R-CEL-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 456215 R-CEL-193711 https://reactome.org/PathwayBrowser/#/R-CEL-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 456215 R-CEL-193727 https://reactome.org/PathwayBrowser/#/R-CEL-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 456215 R-CEL-193743 https://reactome.org/PathwayBrowser/#/R-CEL-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 456215 R-CEL-193766 https://reactome.org/PathwayBrowser/#/R-CEL-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 456215 R-CEL-196753 https://reactome.org/PathwayBrowser/#/R-CEL-196753 2xPPCS ligates PPanK with Cys IEA Caenorhabditis elegans 456215 R-CEL-196761 https://reactome.org/PathwayBrowser/#/R-CEL-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Caenorhabditis elegans 456215 R-CEL-196955 https://reactome.org/PathwayBrowser/#/R-CEL-196955 2xENPP1 hydrolyzes FAD to FMN IEA Caenorhabditis elegans 456215 R-CEL-197271 https://reactome.org/PathwayBrowser/#/R-CEL-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Caenorhabditis elegans 456215 R-CEL-201035 https://reactome.org/PathwayBrowser/#/R-CEL-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Caenorhabditis elegans 456215 R-CEL-2393939 https://reactome.org/PathwayBrowser/#/R-CEL-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 456215 R-CEL-2393954 https://reactome.org/PathwayBrowser/#/R-CEL-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 456215 R-CEL-2990833 https://reactome.org/PathwayBrowser/#/R-CEL-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Caenorhabditis elegans 456215 R-CEL-2993447 https://reactome.org/PathwayBrowser/#/R-CEL-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Caenorhabditis elegans 456215 R-CEL-2993799 https://reactome.org/PathwayBrowser/#/R-CEL-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Caenorhabditis elegans 456215 R-CEL-2993802 https://reactome.org/PathwayBrowser/#/R-CEL-2993802 HLCS biotinylates PC:Mn2+ IEA Caenorhabditis elegans 456215 R-CEL-2993814 https://reactome.org/PathwayBrowser/#/R-CEL-2993814 HLCS biotinylates ACACA:Mn2+ IEA Caenorhabditis elegans 456215 R-CEL-380930 https://reactome.org/PathwayBrowser/#/R-CEL-380930 Phosphorylated AMPK binds AMP IEA Caenorhabditis elegans 456215 R-CEL-389622 https://reactome.org/PathwayBrowser/#/R-CEL-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 456215 R-CEL-389632 https://reactome.org/PathwayBrowser/#/R-CEL-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 456215 R-CEL-4167511 https://reactome.org/PathwayBrowser/#/R-CEL-4167511 HLCS biotinylates ACACB IEA Caenorhabditis elegans 456215 R-CEL-418553 https://reactome.org/PathwayBrowser/#/R-CEL-418553 cAMP degradation by Phosphodiesterases IEA Caenorhabditis elegans 456215 R-CEL-430028 https://reactome.org/PathwayBrowser/#/R-CEL-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Caenorhabditis elegans 456215 R-CEL-434382 https://reactome.org/PathwayBrowser/#/R-CEL-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Caenorhabditis elegans 456215 R-CEL-447074 https://reactome.org/PathwayBrowser/#/R-CEL-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Caenorhabditis elegans 456215 R-CEL-453338 https://reactome.org/PathwayBrowser/#/R-CEL-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP IEA Caenorhabditis elegans 456215 R-CEL-453342 https://reactome.org/PathwayBrowser/#/R-CEL-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Caenorhabditis elegans 456215 R-CEL-5358475 https://reactome.org/PathwayBrowser/#/R-CEL-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Caenorhabditis elegans 456215 R-CEL-5358592 https://reactome.org/PathwayBrowser/#/R-CEL-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Caenorhabditis elegans 456215 R-CEL-548843 https://reactome.org/PathwayBrowser/#/R-CEL-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Caenorhabditis elegans 456215 R-CEL-5631941 https://reactome.org/PathwayBrowser/#/R-CEL-5631941 SESN1,2,3 bind AMPK IEA Caenorhabditis elegans 456215 R-CEL-5665868 https://reactome.org/PathwayBrowser/#/R-CEL-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Caenorhabditis elegans 456215 R-CEL-5672008 https://reactome.org/PathwayBrowser/#/R-CEL-5672008 Thr-180 of ULK1 is phosphorylated IEA Caenorhabditis elegans 456215 R-CEL-5672011 https://reactome.org/PathwayBrowser/#/R-CEL-5672011 p-AMPK:AMP binds the ULK complex IEA Caenorhabditis elegans 456215 R-CEL-5673768 https://reactome.org/PathwayBrowser/#/R-CEL-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Caenorhabditis elegans 456215 R-CEL-5675868 https://reactome.org/PathwayBrowser/#/R-CEL-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Caenorhabditis elegans 456215 R-CEL-5679205 https://reactome.org/PathwayBrowser/#/R-CEL-5679205 ULK1 phosphorylates Beclin-1 IEA Caenorhabditis elegans 456215 R-CEL-5679239 https://reactome.org/PathwayBrowser/#/R-CEL-5679239 ULK complex translocates to the ER IEA Caenorhabditis elegans 456215 R-CEL-5694494 https://reactome.org/PathwayBrowser/#/R-CEL-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Caenorhabditis elegans 456215 R-CEL-5696004 https://reactome.org/PathwayBrowser/#/R-CEL-5696004 ACSF2 ligates CoA-SH to MCFA IEA Caenorhabditis elegans 456215 R-CEL-5696021 https://reactome.org/PathwayBrowser/#/R-CEL-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Caenorhabditis elegans 456215 R-CEL-6788810 https://reactome.org/PathwayBrowser/#/R-CEL-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 456215 R-CEL-6809287 https://reactome.org/PathwayBrowser/#/R-CEL-6809287 NUDT12 hydrolyses NADH to NMNH IEA Caenorhabditis elegans 456215 R-CEL-70467 https://reactome.org/PathwayBrowser/#/R-CEL-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Caenorhabditis elegans 456215 R-CEL-70479 https://reactome.org/PathwayBrowser/#/R-CEL-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Caenorhabditis elegans 456215 R-CEL-70599 https://reactome.org/PathwayBrowser/#/R-CEL-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Caenorhabditis elegans 456215 R-CEL-71735 https://reactome.org/PathwayBrowser/#/R-CEL-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Caenorhabditis elegans 456215 R-CEL-73792 https://reactome.org/PathwayBrowser/#/R-CEL-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Caenorhabditis elegans 456215 R-CEL-73828 https://reactome.org/PathwayBrowser/#/R-CEL-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Caenorhabditis elegans 456215 R-CEL-74213 https://reactome.org/PathwayBrowser/#/R-CEL-74213 APRT catalyzes the conversion of adenine to AMP IEA Caenorhabditis elegans 456215 R-CEL-74220 https://reactome.org/PathwayBrowser/#/R-CEL-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Caenorhabditis elegans 456215 R-CEL-76590 https://reactome.org/PathwayBrowser/#/R-CEL-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Caenorhabditis elegans 456215 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 456215 R-CEL-8852133 https://reactome.org/PathwayBrowser/#/R-CEL-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Caenorhabditis elegans 456215 R-CEL-8852136 https://reactome.org/PathwayBrowser/#/R-CEL-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Caenorhabditis elegans 456215 R-CEL-8951648 https://reactome.org/PathwayBrowser/#/R-CEL-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Caenorhabditis elegans 456215 R-CEL-8951656 https://reactome.org/PathwayBrowser/#/R-CEL-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Caenorhabditis elegans 456215 R-CEL-8953499 https://reactome.org/PathwayBrowser/#/R-CEL-8953499 IMPAD1 hydrolyses PAP to AMP IEA Caenorhabditis elegans 456215 R-CEL-8959510 https://reactome.org/PathwayBrowser/#/R-CEL-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Caenorhabditis elegans 456215 R-CEL-9009950 https://reactome.org/PathwayBrowser/#/R-CEL-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Caenorhabditis elegans 456215 R-CEL-947531 https://reactome.org/PathwayBrowser/#/R-CEL-947531 Molybdenum ion transfer onto molybdopterin IEA Caenorhabditis elegans 456215 R-CEL-9613494 https://reactome.org/PathwayBrowser/#/R-CEL-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Caenorhabditis elegans 456215 R-CEL-9629675 https://reactome.org/PathwayBrowser/#/R-CEL-9629675 PDE3A hydrolyses cAMP to AMP IEA Caenorhabditis elegans 456215 R-CEL-9644869 https://reactome.org/PathwayBrowser/#/R-CEL-9644869 p-S54-PDE4B hydrolyses cAMP IEA Caenorhabditis elegans 456215 R-CEL-9705507 https://reactome.org/PathwayBrowser/#/R-CEL-9705507 PDE3B hydrolyses cAMP to AMP IEA Caenorhabditis elegans 456215 R-CEL-9708261 https://reactome.org/PathwayBrowser/#/R-CEL-9708261 PDE4A hydrolyses cAMP to AMP IEA Caenorhabditis elegans 456215 R-CEL-9734535 https://reactome.org/PathwayBrowser/#/R-CEL-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Caenorhabditis elegans 456215 R-CEL-9748957 https://reactome.org/PathwayBrowser/#/R-CEL-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Caenorhabditis elegans 456215 R-CEL-983140 https://reactome.org/PathwayBrowser/#/R-CEL-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Caenorhabditis elegans 456215 R-CEL-983153 https://reactome.org/PathwayBrowser/#/R-CEL-983153 E1 mediated ubiquitin activation IEA Caenorhabditis elegans 456215 R-CEL-983156 https://reactome.org/PathwayBrowser/#/R-CEL-983156 Polyubiquitination of substrate IEA Caenorhabditis elegans 456215 R-CEL-9833973 https://reactome.org/PathwayBrowser/#/R-CEL-9833973 ISGylation of PKR IEA Caenorhabditis elegans 456215 R-CFA-1008248 https://reactome.org/PathwayBrowser/#/R-CFA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Canis familiaris 456215 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 456215 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 456215 R-CFA-109415 https://reactome.org/PathwayBrowser/#/R-CFA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Canis familiaris 456215 R-CFA-109624 https://reactome.org/PathwayBrowser/#/R-CFA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Canis familiaris 456215 R-CFA-110137 https://reactome.org/PathwayBrowser/#/R-CFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Canis familiaris 456215 R-CFA-110138 https://reactome.org/PathwayBrowser/#/R-CFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 456215 R-CFA-110141 https://reactome.org/PathwayBrowser/#/R-CFA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Canis familiaris 456215 R-CFA-110144 https://reactome.org/PathwayBrowser/#/R-CFA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Canis familiaris 456215 R-CFA-110145 https://reactome.org/PathwayBrowser/#/R-CFA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Canis familiaris 456215 R-CFA-111285 https://reactome.org/PathwayBrowser/#/R-CFA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Canis familiaris 456215 R-CFA-111955 https://reactome.org/PathwayBrowser/#/R-CFA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Canis familiaris 456215 R-CFA-111962 https://reactome.org/PathwayBrowser/#/R-CFA-111962 PDE4A,C,D hydrolyse cAMP IEA Canis familiaris 456215 R-CFA-1169397 https://reactome.org/PathwayBrowser/#/R-CFA-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Canis familiaris 456215 R-CFA-159425 https://reactome.org/PathwayBrowser/#/R-CFA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 456215 R-CFA-159443 https://reactome.org/PathwayBrowser/#/R-CFA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 456215 R-CFA-159567 https://reactome.org/PathwayBrowser/#/R-CFA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Canis familiaris 456215 R-CFA-162425 https://reactome.org/PathwayBrowser/#/R-CFA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Canis familiaris 456215 R-CFA-1632857 https://reactome.org/PathwayBrowser/#/R-CFA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Canis familiaris 456215 R-CFA-163664 https://reactome.org/PathwayBrowser/#/R-CFA-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Canis familiaris 456215 R-CFA-169260 https://reactome.org/PathwayBrowser/#/R-CFA-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Canis familiaris 456215 R-CFA-169270 https://reactome.org/PathwayBrowser/#/R-CFA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Canis familiaris 456215 R-CFA-174441 https://reactome.org/PathwayBrowser/#/R-CFA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Canis familiaris 456215 R-CFA-176606 https://reactome.org/PathwayBrowser/#/R-CFA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Canis familiaris 456215 R-CFA-177157 https://reactome.org/PathwayBrowser/#/R-CFA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Canis familiaris 456215 R-CFA-192137 https://reactome.org/PathwayBrowser/#/R-CFA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 456215 R-CFA-193401 https://reactome.org/PathwayBrowser/#/R-CFA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 456215 R-CFA-193407 https://reactome.org/PathwayBrowser/#/R-CFA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 456215 R-CFA-193424 https://reactome.org/PathwayBrowser/#/R-CFA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 456215 R-CFA-193711 https://reactome.org/PathwayBrowser/#/R-CFA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 456215 R-CFA-193727 https://reactome.org/PathwayBrowser/#/R-CFA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 456215 R-CFA-193743 https://reactome.org/PathwayBrowser/#/R-CFA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 456215 R-CFA-193766 https://reactome.org/PathwayBrowser/#/R-CFA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 456215 R-CFA-196753 https://reactome.org/PathwayBrowser/#/R-CFA-196753 2xPPCS ligates PPanK with Cys IEA Canis familiaris 456215 R-CFA-196761 https://reactome.org/PathwayBrowser/#/R-CFA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Canis familiaris 456215 R-CFA-196955 https://reactome.org/PathwayBrowser/#/R-CFA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Canis familiaris 456215 R-CFA-197271 https://reactome.org/PathwayBrowser/#/R-CFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Canis familiaris 456215 R-CFA-200421 https://reactome.org/PathwayBrowser/#/R-CFA-200421 Activation of cytosolic AMPK by phosphorylation IEA Canis familiaris 456215 R-CFA-201035 https://reactome.org/PathwayBrowser/#/R-CFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Canis familiaris 456215 R-CFA-2046085 https://reactome.org/PathwayBrowser/#/R-CFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Canis familiaris 456215 R-CFA-2046098 https://reactome.org/PathwayBrowser/#/R-CFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Canis familiaris 456215 R-CFA-2393939 https://reactome.org/PathwayBrowser/#/R-CFA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 456215 R-CFA-2393954 https://reactome.org/PathwayBrowser/#/R-CFA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 456215 R-CFA-2730904 https://reactome.org/PathwayBrowser/#/R-CFA-2730904 Auto-ubiquitination of TRAF6 IEA Canis familiaris 456215 R-CFA-2990833 https://reactome.org/PathwayBrowser/#/R-CFA-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Canis familiaris 456215 R-CFA-2993447 https://reactome.org/PathwayBrowser/#/R-CFA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Canis familiaris 456215 R-CFA-2993799 https://reactome.org/PathwayBrowser/#/R-CFA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Canis familiaris 456215 R-CFA-2993802 https://reactome.org/PathwayBrowser/#/R-CFA-2993802 HLCS biotinylates PC:Mn2+ IEA Canis familiaris 456215 R-CFA-2993814 https://reactome.org/PathwayBrowser/#/R-CFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Canis familiaris 456215 R-CFA-380927 https://reactome.org/PathwayBrowser/#/R-CFA-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Canis familiaris 456215 R-CFA-380930 https://reactome.org/PathwayBrowser/#/R-CFA-380930 Phosphorylated AMPK binds AMP IEA Canis familiaris 456215 R-CFA-389622 https://reactome.org/PathwayBrowser/#/R-CFA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 456215 R-CFA-389632 https://reactome.org/PathwayBrowser/#/R-CFA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 456215 R-CFA-389652 https://reactome.org/PathwayBrowser/#/R-CFA-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Canis familiaris 456215 R-CFA-4167511 https://reactome.org/PathwayBrowser/#/R-CFA-4167511 HLCS biotinylates ACACB IEA Canis familiaris 456215 R-CFA-418553 https://reactome.org/PathwayBrowser/#/R-CFA-418553 cAMP degradation by Phosphodiesterases IEA Canis familiaris 456215 R-CFA-429955 https://reactome.org/PathwayBrowser/#/R-CFA-429955 CCR4-NOT complex deadenylates mRNA IEA Canis familiaris 456215 R-CFA-429992 https://reactome.org/PathwayBrowser/#/R-CFA-429992 PARN deadenylates mRNA IEA Canis familiaris 456215 R-CFA-430021 https://reactome.org/PathwayBrowser/#/R-CFA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Canis familiaris 456215 R-CFA-430028 https://reactome.org/PathwayBrowser/#/R-CFA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Canis familiaris 456215 R-CFA-434382 https://reactome.org/PathwayBrowser/#/R-CFA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Canis familiaris 456215 R-CFA-447074 https://reactome.org/PathwayBrowser/#/R-CFA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Canis familiaris 456215 R-CFA-449911 https://reactome.org/PathwayBrowser/#/R-CFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Canis familiaris 456215 R-CFA-453338 https://reactome.org/PathwayBrowser/#/R-CFA-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP IEA Canis familiaris 456215 R-CFA-453342 https://reactome.org/PathwayBrowser/#/R-CFA-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Canis familiaris 456215 R-CFA-5358475 https://reactome.org/PathwayBrowser/#/R-CFA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Canis familiaris 456215 R-CFA-5358592 https://reactome.org/PathwayBrowser/#/R-CFA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Canis familiaris 456215 R-CFA-548843 https://reactome.org/PathwayBrowser/#/R-CFA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Canis familiaris 456215 R-CFA-5607756 https://reactome.org/PathwayBrowser/#/R-CFA-5607756 TRAF6 oligomer autoubiquitinates IEA Canis familiaris 456215 R-CFA-5607757 https://reactome.org/PathwayBrowser/#/R-CFA-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 IEA Canis familiaris 456215 R-CFA-5631941 https://reactome.org/PathwayBrowser/#/R-CFA-5631941 SESN1,2,3 bind AMPK IEA Canis familiaris 456215 R-CFA-5665868 https://reactome.org/PathwayBrowser/#/R-CFA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Canis familiaris 456215 R-CFA-5672008 https://reactome.org/PathwayBrowser/#/R-CFA-5672008 Thr-180 of ULK1 is phosphorylated IEA Canis familiaris 456215 R-CFA-5672011 https://reactome.org/PathwayBrowser/#/R-CFA-5672011 p-AMPK:AMP binds the ULK complex IEA Canis familiaris 456215 R-CFA-5673768 https://reactome.org/PathwayBrowser/#/R-CFA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Canis familiaris 456215 R-CFA-5675868 https://reactome.org/PathwayBrowser/#/R-CFA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Canis familiaris 456215 R-CFA-5679205 https://reactome.org/PathwayBrowser/#/R-CFA-5679205 ULK1 phosphorylates Beclin-1 IEA Canis familiaris 456215 R-CFA-5679239 https://reactome.org/PathwayBrowser/#/R-CFA-5679239 ULK complex translocates to the ER IEA Canis familiaris 456215 R-CFA-5695957 https://reactome.org/PathwayBrowser/#/R-CFA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Canis familiaris 456215 R-CFA-5696004 https://reactome.org/PathwayBrowser/#/R-CFA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Canis familiaris 456215 R-CFA-5696021 https://reactome.org/PathwayBrowser/#/R-CFA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Canis familiaris 456215 R-CFA-5696049 https://reactome.org/PathwayBrowser/#/R-CFA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 456215 R-CFA-6788798 https://reactome.org/PathwayBrowser/#/R-CFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 456215 R-CFA-6788810 https://reactome.org/PathwayBrowser/#/R-CFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 456215 R-CFA-6805470 https://reactome.org/PathwayBrowser/#/R-CFA-6805470 AMPK phosphorylates TP53 IEA Canis familiaris 456215 R-CFA-6809287 https://reactome.org/PathwayBrowser/#/R-CFA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Canis familiaris 456215 R-CFA-69144 https://reactome.org/PathwayBrowser/#/R-CFA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Canis familiaris 456215 R-CFA-70467 https://reactome.org/PathwayBrowser/#/R-CFA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Canis familiaris 456215 R-CFA-70479 https://reactome.org/PathwayBrowser/#/R-CFA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Canis familiaris 456215 R-CFA-70577 https://reactome.org/PathwayBrowser/#/R-CFA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Canis familiaris 456215 R-CFA-70599 https://reactome.org/PathwayBrowser/#/R-CFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Canis familiaris 456215 R-CFA-71735 https://reactome.org/PathwayBrowser/#/R-CFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Canis familiaris 456215 R-CFA-73580 https://reactome.org/PathwayBrowser/#/R-CFA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Canis familiaris 456215 R-CFA-73792 https://reactome.org/PathwayBrowser/#/R-CFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Canis familiaris 456215 R-CFA-73828 https://reactome.org/PathwayBrowser/#/R-CFA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Canis familiaris 456215 R-CFA-74213 https://reactome.org/PathwayBrowser/#/R-CFA-74213 APRT catalyzes the conversion of adenine to AMP IEA Canis familiaris 456215 R-CFA-74220 https://reactome.org/PathwayBrowser/#/R-CFA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Canis familiaris 456215 R-CFA-76590 https://reactome.org/PathwayBrowser/#/R-CFA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Canis familiaris 456215 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 456215 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 456215 R-CFA-8852133 https://reactome.org/PathwayBrowser/#/R-CFA-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Canis familiaris 456215 R-CFA-8852136 https://reactome.org/PathwayBrowser/#/R-CFA-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Canis familiaris 456215 R-CFA-8875071 https://reactome.org/PathwayBrowser/#/R-CFA-8875071 ACSS3 ligates CoA to CH3COO- IEA Canis familiaris 456215 R-CFA-8951648 https://reactome.org/PathwayBrowser/#/R-CFA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Canis familiaris 456215 R-CFA-8951656 https://reactome.org/PathwayBrowser/#/R-CFA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Canis familiaris 456215 R-CFA-8953499 https://reactome.org/PathwayBrowser/#/R-CFA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Canis familiaris 456215 R-CFA-8959510 https://reactome.org/PathwayBrowser/#/R-CFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Canis familiaris 456215 R-CFA-9009950 https://reactome.org/PathwayBrowser/#/R-CFA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Canis familiaris 456215 R-CFA-947531 https://reactome.org/PathwayBrowser/#/R-CFA-947531 Molybdenum ion transfer onto molybdopterin IEA Canis familiaris 456215 R-CFA-9613494 https://reactome.org/PathwayBrowser/#/R-CFA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Canis familiaris 456215 R-CFA-9629675 https://reactome.org/PathwayBrowser/#/R-CFA-9629675 PDE3A hydrolyses cAMP to AMP IEA Canis familiaris 456215 R-CFA-9644869 https://reactome.org/PathwayBrowser/#/R-CFA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Canis familiaris 456215 R-CFA-9705507 https://reactome.org/PathwayBrowser/#/R-CFA-9705507 PDE3B hydrolyses cAMP to AMP IEA Canis familiaris 456215 R-CFA-9708261 https://reactome.org/PathwayBrowser/#/R-CFA-9708261 PDE4A hydrolyses cAMP to AMP IEA Canis familiaris 456215 R-CFA-9734535 https://reactome.org/PathwayBrowser/#/R-CFA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Canis familiaris 456215 R-CFA-9748957 https://reactome.org/PathwayBrowser/#/R-CFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Canis familiaris 456215 R-CFA-9749971 https://reactome.org/PathwayBrowser/#/R-CFA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Canis familiaris 456215 R-CFA-983140 https://reactome.org/PathwayBrowser/#/R-CFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Canis familiaris 456215 R-CFA-983153 https://reactome.org/PathwayBrowser/#/R-CFA-983153 E1 mediated ubiquitin activation IEA Canis familiaris 456215 R-CFA-983156 https://reactome.org/PathwayBrowser/#/R-CFA-983156 Polyubiquitination of substrate IEA Canis familiaris 456215 R-DDI-1008248 https://reactome.org/PathwayBrowser/#/R-DDI-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Dictyostelium discoideum 456215 R-DDI-109624 https://reactome.org/PathwayBrowser/#/R-DDI-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Dictyostelium discoideum 456215 R-DDI-110144 https://reactome.org/PathwayBrowser/#/R-DDI-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Dictyostelium discoideum 456215 R-DDI-110145 https://reactome.org/PathwayBrowser/#/R-DDI-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Dictyostelium discoideum 456215 R-DDI-111955 https://reactome.org/PathwayBrowser/#/R-DDI-111955 cAMP hydrolysis by Cam-PDE 1 IEA Dictyostelium discoideum 456215 R-DDI-111962 https://reactome.org/PathwayBrowser/#/R-DDI-111962 PDE4A,C,D hydrolyse cAMP IEA Dictyostelium discoideum 456215 R-DDI-1169397 https://reactome.org/PathwayBrowser/#/R-DDI-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Dictyostelium discoideum 456215 R-DDI-1169398 https://reactome.org/PathwayBrowser/#/R-DDI-1169398 ISGylation of host protein filamin B IEA Dictyostelium discoideum 456215 R-DDI-1169402 https://reactome.org/PathwayBrowser/#/R-DDI-1169402 ISGylation of E2 conjugating enzymes IEA Dictyostelium discoideum 456215 R-DDI-1169406 https://reactome.org/PathwayBrowser/#/R-DDI-1169406 ISGylation of host proteins IEA Dictyostelium discoideum 456215 R-DDI-162425 https://reactome.org/PathwayBrowser/#/R-DDI-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Dictyostelium discoideum 456215 R-DDI-163664 https://reactome.org/PathwayBrowser/#/R-DDI-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Dictyostelium discoideum 456215 R-DDI-169260 https://reactome.org/PathwayBrowser/#/R-DDI-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Dictyostelium discoideum 456215 R-DDI-169270 https://reactome.org/PathwayBrowser/#/R-DDI-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Dictyostelium discoideum 456215 R-DDI-176606 https://reactome.org/PathwayBrowser/#/R-DDI-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Dictyostelium discoideum 456215 R-DDI-196753 https://reactome.org/PathwayBrowser/#/R-DDI-196753 2xPPCS ligates PPanK with Cys IEA Dictyostelium discoideum 456215 R-DDI-196761 https://reactome.org/PathwayBrowser/#/R-DDI-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Dictyostelium discoideum 456215 R-DDI-196955 https://reactome.org/PathwayBrowser/#/R-DDI-196955 2xENPP1 hydrolyzes FAD to FMN IEA Dictyostelium discoideum 456215 R-DDI-197271 https://reactome.org/PathwayBrowser/#/R-DDI-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Dictyostelium discoideum 456215 R-DDI-201035 https://reactome.org/PathwayBrowser/#/R-DDI-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Dictyostelium discoideum 456215 R-DDI-2046085 https://reactome.org/PathwayBrowser/#/R-DDI-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Dictyostelium discoideum 456215 R-DDI-2046098 https://reactome.org/PathwayBrowser/#/R-DDI-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Dictyostelium discoideum 456215 R-DDI-2393939 https://reactome.org/PathwayBrowser/#/R-DDI-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Dictyostelium discoideum 456215 R-DDI-2990833 https://reactome.org/PathwayBrowser/#/R-DDI-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Dictyostelium discoideum 456215 R-DDI-2993447 https://reactome.org/PathwayBrowser/#/R-DDI-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Dictyostelium discoideum 456215 R-DDI-2993799 https://reactome.org/PathwayBrowser/#/R-DDI-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Dictyostelium discoideum 456215 R-DDI-2993814 https://reactome.org/PathwayBrowser/#/R-DDI-2993814 HLCS biotinylates ACACA:Mn2+ IEA Dictyostelium discoideum 456215 R-DDI-380930 https://reactome.org/PathwayBrowser/#/R-DDI-380930 Phosphorylated AMPK binds AMP IEA Dictyostelium discoideum 456215 R-DDI-389652 https://reactome.org/PathwayBrowser/#/R-DDI-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Dictyostelium discoideum 456215 R-DDI-4167511 https://reactome.org/PathwayBrowser/#/R-DDI-4167511 HLCS biotinylates ACACB IEA Dictyostelium discoideum 456215 R-DDI-418553 https://reactome.org/PathwayBrowser/#/R-DDI-418553 cAMP degradation by Phosphodiesterases IEA Dictyostelium discoideum 456215 R-DDI-430028 https://reactome.org/PathwayBrowser/#/R-DDI-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Dictyostelium discoideum 456215 R-DDI-447074 https://reactome.org/PathwayBrowser/#/R-DDI-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Dictyostelium discoideum 456215 R-DDI-449911 https://reactome.org/PathwayBrowser/#/R-DDI-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Dictyostelium discoideum 456215 R-DDI-453338 https://reactome.org/PathwayBrowser/#/R-DDI-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP IEA Dictyostelium discoideum 456215 R-DDI-453342 https://reactome.org/PathwayBrowser/#/R-DDI-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Dictyostelium discoideum 456215 R-DDI-5358475 https://reactome.org/PathwayBrowser/#/R-DDI-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Dictyostelium discoideum 456215 R-DDI-5358592 https://reactome.org/PathwayBrowser/#/R-DDI-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Dictyostelium discoideum 456215 R-DDI-5631941 https://reactome.org/PathwayBrowser/#/R-DDI-5631941 SESN1,2,3 bind AMPK IEA Dictyostelium discoideum 456215 R-DDI-5665868 https://reactome.org/PathwayBrowser/#/R-DDI-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Dictyostelium discoideum 456215 R-DDI-5672008 https://reactome.org/PathwayBrowser/#/R-DDI-5672008 Thr-180 of ULK1 is phosphorylated IEA Dictyostelium discoideum 456215 R-DDI-5672011 https://reactome.org/PathwayBrowser/#/R-DDI-5672011 p-AMPK:AMP binds the ULK complex IEA Dictyostelium discoideum 456215 R-DDI-5673768 https://reactome.org/PathwayBrowser/#/R-DDI-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Dictyostelium discoideum 456215 R-DDI-5675868 https://reactome.org/PathwayBrowser/#/R-DDI-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Dictyostelium discoideum 456215 R-DDI-5679205 https://reactome.org/PathwayBrowser/#/R-DDI-5679205 ULK1 phosphorylates Beclin-1 IEA Dictyostelium discoideum 456215 R-DDI-5679239 https://reactome.org/PathwayBrowser/#/R-DDI-5679239 ULK complex translocates to the ER IEA Dictyostelium discoideum 456215 R-DDI-5695957 https://reactome.org/PathwayBrowser/#/R-DDI-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Dictyostelium discoideum 456215 R-DDI-5696007 https://reactome.org/PathwayBrowser/#/R-DDI-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Dictyostelium discoideum 456215 R-DDI-5696021 https://reactome.org/PathwayBrowser/#/R-DDI-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Dictyostelium discoideum 456215 R-DDI-6788798 https://reactome.org/PathwayBrowser/#/R-DDI-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 456215 R-DDI-6788810 https://reactome.org/PathwayBrowser/#/R-DDI-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 456215 R-DDI-6809287 https://reactome.org/PathwayBrowser/#/R-DDI-6809287 NUDT12 hydrolyses NADH to NMNH IEA Dictyostelium discoideum 456215 R-DDI-70479 https://reactome.org/PathwayBrowser/#/R-DDI-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Dictyostelium discoideum 456215 R-DDI-70599 https://reactome.org/PathwayBrowser/#/R-DDI-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Dictyostelium discoideum 456215 R-DDI-71735 https://reactome.org/PathwayBrowser/#/R-DDI-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Dictyostelium discoideum 456215 R-DDI-73580 https://reactome.org/PathwayBrowser/#/R-DDI-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Dictyostelium discoideum 456215 R-DDI-73792 https://reactome.org/PathwayBrowser/#/R-DDI-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Dictyostelium discoideum 456215 R-DDI-76590 https://reactome.org/PathwayBrowser/#/R-DDI-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Dictyostelium discoideum 456215 R-DDI-8852133 https://reactome.org/PathwayBrowser/#/R-DDI-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Dictyostelium discoideum 456215 R-DDI-8852136 https://reactome.org/PathwayBrowser/#/R-DDI-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Dictyostelium discoideum 456215 R-DDI-8875071 https://reactome.org/PathwayBrowser/#/R-DDI-8875071 ACSS3 ligates CoA to CH3COO- IEA Dictyostelium discoideum 456215 R-DDI-8951648 https://reactome.org/PathwayBrowser/#/R-DDI-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Dictyostelium discoideum 456215 R-DDI-8951656 https://reactome.org/PathwayBrowser/#/R-DDI-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Dictyostelium discoideum 456215 R-DDI-8953499 https://reactome.org/PathwayBrowser/#/R-DDI-8953499 IMPAD1 hydrolyses PAP to AMP IEA Dictyostelium discoideum 456215 R-DDI-8959510 https://reactome.org/PathwayBrowser/#/R-DDI-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Dictyostelium discoideum 456215 R-DDI-947531 https://reactome.org/PathwayBrowser/#/R-DDI-947531 Molybdenum ion transfer onto molybdopterin IEA Dictyostelium discoideum 456215 R-DDI-9613494 https://reactome.org/PathwayBrowser/#/R-DDI-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Dictyostelium discoideum 456215 R-DDI-9629675 https://reactome.org/PathwayBrowser/#/R-DDI-9629675 PDE3A hydrolyses cAMP to AMP IEA Dictyostelium discoideum 456215 R-DDI-9644869 https://reactome.org/PathwayBrowser/#/R-DDI-9644869 p-S54-PDE4B hydrolyses cAMP IEA Dictyostelium discoideum 456215 R-DDI-9705507 https://reactome.org/PathwayBrowser/#/R-DDI-9705507 PDE3B hydrolyses cAMP to AMP IEA Dictyostelium discoideum 456215 R-DDI-9708261 https://reactome.org/PathwayBrowser/#/R-DDI-9708261 PDE4A hydrolyses cAMP to AMP IEA Dictyostelium discoideum 456215 R-DDI-9748957 https://reactome.org/PathwayBrowser/#/R-DDI-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Dictyostelium discoideum 456215 R-DDI-983140 https://reactome.org/PathwayBrowser/#/R-DDI-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Dictyostelium discoideum 456215 R-DDI-983153 https://reactome.org/PathwayBrowser/#/R-DDI-983153 E1 mediated ubiquitin activation IEA Dictyostelium discoideum 456215 R-DDI-983156 https://reactome.org/PathwayBrowser/#/R-DDI-983156 Polyubiquitination of substrate IEA Dictyostelium discoideum 456215 R-DME-1008248 https://reactome.org/PathwayBrowser/#/R-DME-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Drosophila melanogaster 456215 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 456215 R-DME-109624 https://reactome.org/PathwayBrowser/#/R-DME-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Drosophila melanogaster 456215 R-DME-110137 https://reactome.org/PathwayBrowser/#/R-DME-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Drosophila melanogaster 456215 R-DME-110138 https://reactome.org/PathwayBrowser/#/R-DME-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 456215 R-DME-110141 https://reactome.org/PathwayBrowser/#/R-DME-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Drosophila melanogaster 456215 R-DME-110144 https://reactome.org/PathwayBrowser/#/R-DME-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Drosophila melanogaster 456215 R-DME-110145 https://reactome.org/PathwayBrowser/#/R-DME-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Drosophila melanogaster 456215 R-DME-111285 https://reactome.org/PathwayBrowser/#/R-DME-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Drosophila melanogaster 456215 R-DME-111955 https://reactome.org/PathwayBrowser/#/R-DME-111955 cAMP hydrolysis by Cam-PDE 1 IEA Drosophila melanogaster 456215 R-DME-111962 https://reactome.org/PathwayBrowser/#/R-DME-111962 PDE4A,C,D hydrolyse cAMP IEA Drosophila melanogaster 456215 R-DME-1169397 https://reactome.org/PathwayBrowser/#/R-DME-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Drosophila melanogaster 456215 R-DME-1169398 https://reactome.org/PathwayBrowser/#/R-DME-1169398 ISGylation of host protein filamin B IEA Drosophila melanogaster 456215 R-DME-1169402 https://reactome.org/PathwayBrowser/#/R-DME-1169402 ISGylation of E2 conjugating enzymes IEA Drosophila melanogaster 456215 R-DME-1169405 https://reactome.org/PathwayBrowser/#/R-DME-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Drosophila melanogaster 456215 R-DME-1169406 https://reactome.org/PathwayBrowser/#/R-DME-1169406 ISGylation of host proteins IEA Drosophila melanogaster 456215 R-DME-159425 https://reactome.org/PathwayBrowser/#/R-DME-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 456215 R-DME-1632857 https://reactome.org/PathwayBrowser/#/R-DME-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Drosophila melanogaster 456215 R-DME-163664 https://reactome.org/PathwayBrowser/#/R-DME-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Drosophila melanogaster 456215 R-DME-169260 https://reactome.org/PathwayBrowser/#/R-DME-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Drosophila melanogaster 456215 R-DME-169270 https://reactome.org/PathwayBrowser/#/R-DME-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Drosophila melanogaster 456215 R-DME-176606 https://reactome.org/PathwayBrowser/#/R-DME-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Drosophila melanogaster 456215 R-DME-192137 https://reactome.org/PathwayBrowser/#/R-DME-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 456215 R-DME-193401 https://reactome.org/PathwayBrowser/#/R-DME-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 456215 R-DME-193407 https://reactome.org/PathwayBrowser/#/R-DME-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 456215 R-DME-193424 https://reactome.org/PathwayBrowser/#/R-DME-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 456215 R-DME-193711 https://reactome.org/PathwayBrowser/#/R-DME-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 456215 R-DME-193727 https://reactome.org/PathwayBrowser/#/R-DME-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 456215 R-DME-193743 https://reactome.org/PathwayBrowser/#/R-DME-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 456215 R-DME-193766 https://reactome.org/PathwayBrowser/#/R-DME-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 456215 R-DME-196753 https://reactome.org/PathwayBrowser/#/R-DME-196753 2xPPCS ligates PPanK with Cys IEA Drosophila melanogaster 456215 R-DME-196761 https://reactome.org/PathwayBrowser/#/R-DME-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Drosophila melanogaster 456215 R-DME-197271 https://reactome.org/PathwayBrowser/#/R-DME-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Drosophila melanogaster 456215 R-DME-201035 https://reactome.org/PathwayBrowser/#/R-DME-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Drosophila melanogaster 456215 R-DME-2393954 https://reactome.org/PathwayBrowser/#/R-DME-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Drosophila melanogaster 456215 R-DME-2993799 https://reactome.org/PathwayBrowser/#/R-DME-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Drosophila melanogaster 456215 R-DME-2993802 https://reactome.org/PathwayBrowser/#/R-DME-2993802 HLCS biotinylates PC:Mn2+ IEA Drosophila melanogaster 456215 R-DME-2993814 https://reactome.org/PathwayBrowser/#/R-DME-2993814 HLCS biotinylates ACACA:Mn2+ IEA Drosophila melanogaster 456215 R-DME-380927 https://reactome.org/PathwayBrowser/#/R-DME-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Drosophila melanogaster 456215 R-DME-380930 https://reactome.org/PathwayBrowser/#/R-DME-380930 Phosphorylated AMPK binds AMP IEA Drosophila melanogaster 456215 R-DME-389622 https://reactome.org/PathwayBrowser/#/R-DME-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 456215 R-DME-389632 https://reactome.org/PathwayBrowser/#/R-DME-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 456215 R-DME-389652 https://reactome.org/PathwayBrowser/#/R-DME-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Drosophila melanogaster 456215 R-DME-4167511 https://reactome.org/PathwayBrowser/#/R-DME-4167511 HLCS biotinylates ACACB IEA Drosophila melanogaster 456215 R-DME-418553 https://reactome.org/PathwayBrowser/#/R-DME-418553 cAMP degradation by Phosphodiesterases IEA Drosophila melanogaster 456215 R-DME-430028 https://reactome.org/PathwayBrowser/#/R-DME-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Drosophila melanogaster 456215 R-DME-434382 https://reactome.org/PathwayBrowser/#/R-DME-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Drosophila melanogaster 456215 R-DME-447074 https://reactome.org/PathwayBrowser/#/R-DME-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Drosophila melanogaster 456215 R-DME-453338 https://reactome.org/PathwayBrowser/#/R-DME-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP IEA Drosophila melanogaster 456215 R-DME-453342 https://reactome.org/PathwayBrowser/#/R-DME-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Drosophila melanogaster 456215 R-DME-5358475 https://reactome.org/PathwayBrowser/#/R-DME-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Drosophila melanogaster 456215 R-DME-5358592 https://reactome.org/PathwayBrowser/#/R-DME-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Drosophila melanogaster 456215 R-DME-548843 https://reactome.org/PathwayBrowser/#/R-DME-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Drosophila melanogaster 456215 R-DME-5631941 https://reactome.org/PathwayBrowser/#/R-DME-5631941 SESN1,2,3 bind AMPK IEA Drosophila melanogaster 456215 R-DME-5665868 https://reactome.org/PathwayBrowser/#/R-DME-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Drosophila melanogaster 456215 R-DME-5672008 https://reactome.org/PathwayBrowser/#/R-DME-5672008 Thr-180 of ULK1 is phosphorylated IEA Drosophila melanogaster 456215 R-DME-5672011 https://reactome.org/PathwayBrowser/#/R-DME-5672011 p-AMPK:AMP binds the ULK complex IEA Drosophila melanogaster 456215 R-DME-5673768 https://reactome.org/PathwayBrowser/#/R-DME-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Drosophila melanogaster 456215 R-DME-5675868 https://reactome.org/PathwayBrowser/#/R-DME-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Drosophila melanogaster 456215 R-DME-5679205 https://reactome.org/PathwayBrowser/#/R-DME-5679205 ULK1 phosphorylates Beclin-1 IEA Drosophila melanogaster 456215 R-DME-5679239 https://reactome.org/PathwayBrowser/#/R-DME-5679239 ULK complex translocates to the ER IEA Drosophila melanogaster 456215 R-DME-5695957 https://reactome.org/PathwayBrowser/#/R-DME-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Drosophila melanogaster 456215 R-DME-5696004 https://reactome.org/PathwayBrowser/#/R-DME-5696004 ACSF2 ligates CoA-SH to MCFA IEA Drosophila melanogaster 456215 R-DME-5696007 https://reactome.org/PathwayBrowser/#/R-DME-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Drosophila melanogaster 456215 R-DME-6788798 https://reactome.org/PathwayBrowser/#/R-DME-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 456215 R-DME-6788810 https://reactome.org/PathwayBrowser/#/R-DME-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 456215 R-DME-6805470 https://reactome.org/PathwayBrowser/#/R-DME-6805470 AMPK phosphorylates TP53 IEA Drosophila melanogaster 456215 R-DME-69144 https://reactome.org/PathwayBrowser/#/R-DME-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Drosophila melanogaster 456215 R-DME-70467 https://reactome.org/PathwayBrowser/#/R-DME-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Drosophila melanogaster 456215 R-DME-70479 https://reactome.org/PathwayBrowser/#/R-DME-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Drosophila melanogaster 456215 R-DME-71735 https://reactome.org/PathwayBrowser/#/R-DME-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Drosophila melanogaster 456215 R-DME-73792 https://reactome.org/PathwayBrowser/#/R-DME-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Drosophila melanogaster 456215 R-DME-73828 https://reactome.org/PathwayBrowser/#/R-DME-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Drosophila melanogaster 456215 R-DME-74213 https://reactome.org/PathwayBrowser/#/R-DME-74213 APRT catalyzes the conversion of adenine to AMP IEA Drosophila melanogaster 456215 R-DME-74220 https://reactome.org/PathwayBrowser/#/R-DME-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Drosophila melanogaster 456215 R-DME-76590 https://reactome.org/PathwayBrowser/#/R-DME-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Drosophila melanogaster 456215 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 456215 R-DME-8852133 https://reactome.org/PathwayBrowser/#/R-DME-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Drosophila melanogaster 456215 R-DME-8852136 https://reactome.org/PathwayBrowser/#/R-DME-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Drosophila melanogaster 456215 R-DME-8875071 https://reactome.org/PathwayBrowser/#/R-DME-8875071 ACSS3 ligates CoA to CH3COO- IEA Drosophila melanogaster 456215 R-DME-8951648 https://reactome.org/PathwayBrowser/#/R-DME-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Drosophila melanogaster 456215 R-DME-8951656 https://reactome.org/PathwayBrowser/#/R-DME-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Drosophila melanogaster 456215 R-DME-8953499 https://reactome.org/PathwayBrowser/#/R-DME-8953499 IMPAD1 hydrolyses PAP to AMP IEA Drosophila melanogaster 456215 R-DME-8959510 https://reactome.org/PathwayBrowser/#/R-DME-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Drosophila melanogaster 456215 R-DME-9009950 https://reactome.org/PathwayBrowser/#/R-DME-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Drosophila melanogaster 456215 R-DME-947531 https://reactome.org/PathwayBrowser/#/R-DME-947531 Molybdenum ion transfer onto molybdopterin IEA Drosophila melanogaster 456215 R-DME-9613494 https://reactome.org/PathwayBrowser/#/R-DME-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Drosophila melanogaster 456215 R-DME-9644869 https://reactome.org/PathwayBrowser/#/R-DME-9644869 p-S54-PDE4B hydrolyses cAMP IEA Drosophila melanogaster 456215 R-DME-9708261 https://reactome.org/PathwayBrowser/#/R-DME-9708261 PDE4A hydrolyses cAMP to AMP IEA Drosophila melanogaster 456215 R-DME-9734535 https://reactome.org/PathwayBrowser/#/R-DME-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Drosophila melanogaster 456215 R-DME-9748957 https://reactome.org/PathwayBrowser/#/R-DME-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Drosophila melanogaster 456215 R-DME-983140 https://reactome.org/PathwayBrowser/#/R-DME-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Drosophila melanogaster 456215 R-DME-983153 https://reactome.org/PathwayBrowser/#/R-DME-983153 E1 mediated ubiquitin activation IEA Drosophila melanogaster 456215 R-DME-983156 https://reactome.org/PathwayBrowser/#/R-DME-983156 Polyubiquitination of substrate IEA Drosophila melanogaster 456215 R-DME-9833973 https://reactome.org/PathwayBrowser/#/R-DME-9833973 ISGylation of PKR IEA Drosophila melanogaster 456215 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 456215 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 456215 R-DRE-109415 https://reactome.org/PathwayBrowser/#/R-DRE-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Danio rerio 456215 R-DRE-109624 https://reactome.org/PathwayBrowser/#/R-DRE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Danio rerio 456215 R-DRE-110137 https://reactome.org/PathwayBrowser/#/R-DRE-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Danio rerio 456215 R-DRE-110138 https://reactome.org/PathwayBrowser/#/R-DRE-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 456215 R-DRE-110144 https://reactome.org/PathwayBrowser/#/R-DRE-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Danio rerio 456215 R-DRE-110145 https://reactome.org/PathwayBrowser/#/R-DRE-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Danio rerio 456215 R-DRE-111285 https://reactome.org/PathwayBrowser/#/R-DRE-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Danio rerio 456215 R-DRE-159425 https://reactome.org/PathwayBrowser/#/R-DRE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 456215 R-DRE-159443 https://reactome.org/PathwayBrowser/#/R-DRE-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Danio rerio 456215 R-DRE-159567 https://reactome.org/PathwayBrowser/#/R-DRE-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Danio rerio 456215 R-DRE-169260 https://reactome.org/PathwayBrowser/#/R-DRE-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Danio rerio 456215 R-DRE-169270 https://reactome.org/PathwayBrowser/#/R-DRE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Danio rerio 456215 R-DRE-177157 https://reactome.org/PathwayBrowser/#/R-DRE-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Danio rerio 456215 R-DRE-192137 https://reactome.org/PathwayBrowser/#/R-DRE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 456215 R-DRE-193407 https://reactome.org/PathwayBrowser/#/R-DRE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 456215 R-DRE-193711 https://reactome.org/PathwayBrowser/#/R-DRE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 456215 R-DRE-193766 https://reactome.org/PathwayBrowser/#/R-DRE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 456215 R-DRE-196753 https://reactome.org/PathwayBrowser/#/R-DRE-196753 2xPPCS ligates PPanK with Cys IEA Danio rerio 456215 R-DRE-196761 https://reactome.org/PathwayBrowser/#/R-DRE-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Danio rerio 456215 R-DRE-196955 https://reactome.org/PathwayBrowser/#/R-DRE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Danio rerio 456215 R-DRE-197271 https://reactome.org/PathwayBrowser/#/R-DRE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Danio rerio 456215 R-DRE-201035 https://reactome.org/PathwayBrowser/#/R-DRE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Danio rerio 456215 R-DRE-2046085 https://reactome.org/PathwayBrowser/#/R-DRE-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Danio rerio 456215 R-DRE-2046098 https://reactome.org/PathwayBrowser/#/R-DRE-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Danio rerio 456215 R-DRE-2393939 https://reactome.org/PathwayBrowser/#/R-DRE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 456215 R-DRE-2990833 https://reactome.org/PathwayBrowser/#/R-DRE-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Danio rerio 456215 R-DRE-380930 https://reactome.org/PathwayBrowser/#/R-DRE-380930 Phosphorylated AMPK binds AMP IEA Danio rerio 456215 R-DRE-418553 https://reactome.org/PathwayBrowser/#/R-DRE-418553 cAMP degradation by Phosphodiesterases IEA Danio rerio 456215 R-DRE-434382 https://reactome.org/PathwayBrowser/#/R-DRE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Danio rerio 456215 R-DRE-447074 https://reactome.org/PathwayBrowser/#/R-DRE-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Danio rerio 456215 R-DRE-453338 https://reactome.org/PathwayBrowser/#/R-DRE-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP IEA Danio rerio 456215 R-DRE-453342 https://reactome.org/PathwayBrowser/#/R-DRE-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Danio rerio 456215 R-DRE-548843 https://reactome.org/PathwayBrowser/#/R-DRE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Danio rerio 456215 R-DRE-5631941 https://reactome.org/PathwayBrowser/#/R-DRE-5631941 SESN1,2,3 bind AMPK IEA Danio rerio 456215 R-DRE-5673768 https://reactome.org/PathwayBrowser/#/R-DRE-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Danio rerio 456215 R-DRE-5694494 https://reactome.org/PathwayBrowser/#/R-DRE-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Danio rerio 456215 R-DRE-5696004 https://reactome.org/PathwayBrowser/#/R-DRE-5696004 ACSF2 ligates CoA-SH to MCFA IEA Danio rerio 456215 R-DRE-5696021 https://reactome.org/PathwayBrowser/#/R-DRE-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Danio rerio 456215 R-DRE-5696049 https://reactome.org/PathwayBrowser/#/R-DRE-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 456215 R-DRE-6788798 https://reactome.org/PathwayBrowser/#/R-DRE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 456215 R-DRE-6788810 https://reactome.org/PathwayBrowser/#/R-DRE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 456215 R-DRE-6805470 https://reactome.org/PathwayBrowser/#/R-DRE-6805470 AMPK phosphorylates TP53 IEA Danio rerio 456215 R-DRE-6809287 https://reactome.org/PathwayBrowser/#/R-DRE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Danio rerio 456215 R-DRE-70467 https://reactome.org/PathwayBrowser/#/R-DRE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Danio rerio 456215 R-DRE-70479 https://reactome.org/PathwayBrowser/#/R-DRE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Danio rerio 456215 R-DRE-73580 https://reactome.org/PathwayBrowser/#/R-DRE-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Danio rerio 456215 R-DRE-74213 https://reactome.org/PathwayBrowser/#/R-DRE-74213 APRT catalyzes the conversion of adenine to AMP IEA Danio rerio 456215 R-DRE-76590 https://reactome.org/PathwayBrowser/#/R-DRE-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Danio rerio 456215 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 456215 R-DRE-8852133 https://reactome.org/PathwayBrowser/#/R-DRE-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Danio rerio 456215 R-DRE-8852136 https://reactome.org/PathwayBrowser/#/R-DRE-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Danio rerio 456215 R-DRE-8951648 https://reactome.org/PathwayBrowser/#/R-DRE-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Danio rerio 456215 R-DRE-8951656 https://reactome.org/PathwayBrowser/#/R-DRE-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Danio rerio 456215 R-DRE-8953499 https://reactome.org/PathwayBrowser/#/R-DRE-8953499 IMPAD1 hydrolyses PAP to AMP IEA Danio rerio 456215 R-DRE-8959510 https://reactome.org/PathwayBrowser/#/R-DRE-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Danio rerio 456215 R-DRE-9749971 https://reactome.org/PathwayBrowser/#/R-DRE-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Danio rerio 456215 R-DRE-983140 https://reactome.org/PathwayBrowser/#/R-DRE-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Danio rerio 456215 R-DRE-983153 https://reactome.org/PathwayBrowser/#/R-DRE-983153 E1 mediated ubiquitin activation IEA Danio rerio 456215 R-DRE-983156 https://reactome.org/PathwayBrowser/#/R-DRE-983156 Polyubiquitination of substrate IEA Danio rerio 456215 R-GGA-1008248 https://reactome.org/PathwayBrowser/#/R-GGA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Gallus gallus 456215 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 456215 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 456215 R-GGA-109415 https://reactome.org/PathwayBrowser/#/R-GGA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Gallus gallus 456215 R-GGA-109624 https://reactome.org/PathwayBrowser/#/R-GGA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Gallus gallus 456215 R-GGA-110137 https://reactome.org/PathwayBrowser/#/R-GGA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Gallus gallus 456215 R-GGA-110138 https://reactome.org/PathwayBrowser/#/R-GGA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 456215 R-GGA-110141 https://reactome.org/PathwayBrowser/#/R-GGA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Gallus gallus 456215 R-GGA-110144 https://reactome.org/PathwayBrowser/#/R-GGA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Gallus gallus 456215 R-GGA-110145 https://reactome.org/PathwayBrowser/#/R-GGA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Gallus gallus 456215 R-GGA-111285 https://reactome.org/PathwayBrowser/#/R-GGA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Gallus gallus 456215 R-GGA-111955 https://reactome.org/PathwayBrowser/#/R-GGA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Gallus gallus 456215 R-GGA-111962 https://reactome.org/PathwayBrowser/#/R-GGA-111962 PDE4A,C,D hydrolyse cAMP IEA Gallus gallus 456215 R-GGA-159425 https://reactome.org/PathwayBrowser/#/R-GGA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 456215 R-GGA-159443 https://reactome.org/PathwayBrowser/#/R-GGA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 456215 R-GGA-159567 https://reactome.org/PathwayBrowser/#/R-GGA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Gallus gallus 456215 R-GGA-162425 https://reactome.org/PathwayBrowser/#/R-GGA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Gallus gallus 456215 R-GGA-1632857 https://reactome.org/PathwayBrowser/#/R-GGA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Gallus gallus 456215 R-GGA-163664 https://reactome.org/PathwayBrowser/#/R-GGA-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Gallus gallus 456215 R-GGA-176606 https://reactome.org/PathwayBrowser/#/R-GGA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Gallus gallus 456215 R-GGA-177157 https://reactome.org/PathwayBrowser/#/R-GGA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Gallus gallus 456215 R-GGA-192137 https://reactome.org/PathwayBrowser/#/R-GGA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 456215 R-GGA-193401 https://reactome.org/PathwayBrowser/#/R-GGA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 456215 R-GGA-193407 https://reactome.org/PathwayBrowser/#/R-GGA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 456215 R-GGA-193424 https://reactome.org/PathwayBrowser/#/R-GGA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 456215 R-GGA-193711 https://reactome.org/PathwayBrowser/#/R-GGA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 456215 R-GGA-193727 https://reactome.org/PathwayBrowser/#/R-GGA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 456215 R-GGA-193743 https://reactome.org/PathwayBrowser/#/R-GGA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 456215 R-GGA-193766 https://reactome.org/PathwayBrowser/#/R-GGA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 456215 R-GGA-196753 https://reactome.org/PathwayBrowser/#/R-GGA-196753 2xPPCS ligates PPanK with Cys IEA Gallus gallus 456215 R-GGA-196761 https://reactome.org/PathwayBrowser/#/R-GGA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Gallus gallus 456215 R-GGA-197271 https://reactome.org/PathwayBrowser/#/R-GGA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Gallus gallus 456215 R-GGA-200421 https://reactome.org/PathwayBrowser/#/R-GGA-200421 Activation of cytosolic AMPK by phosphorylation IEA Gallus gallus 456215 R-GGA-201035 https://reactome.org/PathwayBrowser/#/R-GGA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Gallus gallus 456215 R-GGA-2046085 https://reactome.org/PathwayBrowser/#/R-GGA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Gallus gallus 456215 R-GGA-2046098 https://reactome.org/PathwayBrowser/#/R-GGA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Gallus gallus 456215 R-GGA-2393939 https://reactome.org/PathwayBrowser/#/R-GGA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 456215 R-GGA-2393954 https://reactome.org/PathwayBrowser/#/R-GGA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 456215 R-GGA-2990833 https://reactome.org/PathwayBrowser/#/R-GGA-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Gallus gallus 456215 R-GGA-2993447 https://reactome.org/PathwayBrowser/#/R-GGA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Gallus gallus 456215 R-GGA-2993799 https://reactome.org/PathwayBrowser/#/R-GGA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Gallus gallus 456215 R-GGA-2993814 https://reactome.org/PathwayBrowser/#/R-GGA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Gallus gallus 456215 R-GGA-380930 https://reactome.org/PathwayBrowser/#/R-GGA-380930 Phosphorylated AMPK binds AMP IEA Gallus gallus 456215 R-GGA-389622 https://reactome.org/PathwayBrowser/#/R-GGA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 456215 R-GGA-389632 https://reactome.org/PathwayBrowser/#/R-GGA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 456215 R-GGA-389652 https://reactome.org/PathwayBrowser/#/R-GGA-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Gallus gallus 456215 R-GGA-418553 https://reactome.org/PathwayBrowser/#/R-GGA-418553 cAMP degradation by Phosphodiesterases IEA Gallus gallus 456215 R-GGA-420906 https://reactome.org/PathwayBrowser/#/R-GGA-420906 Formation of PPAT tetramers TAS Gallus gallus 456215 R-GGA-420911 https://reactome.org/PathwayBrowser/#/R-GGA-420911 Formation of PPAT dimers IEA Gallus gallus 456215 R-GGA-421197 https://reactome.org/PathwayBrowser/#/R-GGA-421197 adenylosuccinate => adenosine 5'-monophosphate (AMP) + fumarate IEA Gallus gallus 456215 R-GGA-421218 https://reactome.org/PathwayBrowser/#/R-GGA-421218 xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate IEA Gallus gallus 456215 R-GGA-429955 https://reactome.org/PathwayBrowser/#/R-GGA-429955 CCR4-NOT complex deadenylates mRNA IEA Gallus gallus 456215 R-GGA-429992 https://reactome.org/PathwayBrowser/#/R-GGA-429992 PARN deadenylates mRNA IEA Gallus gallus 456215 R-GGA-430021 https://reactome.org/PathwayBrowser/#/R-GGA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Gallus gallus 456215 R-GGA-430028 https://reactome.org/PathwayBrowser/#/R-GGA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Gallus gallus 456215 R-GGA-434382 https://reactome.org/PathwayBrowser/#/R-GGA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Gallus gallus 456215 R-GGA-447074 https://reactome.org/PathwayBrowser/#/R-GGA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Gallus gallus 456215 R-GGA-449911 https://reactome.org/PathwayBrowser/#/R-GGA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Gallus gallus 456215 R-GGA-5358475 https://reactome.org/PathwayBrowser/#/R-GGA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Gallus gallus 456215 R-GGA-5358592 https://reactome.org/PathwayBrowser/#/R-GGA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Gallus gallus 456215 R-GGA-548843 https://reactome.org/PathwayBrowser/#/R-GGA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Gallus gallus 456215 R-GGA-5631941 https://reactome.org/PathwayBrowser/#/R-GGA-5631941 SESN1,2,3 bind AMPK IEA Gallus gallus 456215 R-GGA-5665868 https://reactome.org/PathwayBrowser/#/R-GGA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Gallus gallus 456215 R-GGA-5672008 https://reactome.org/PathwayBrowser/#/R-GGA-5672008 Thr-180 of ULK1 is phosphorylated IEA Gallus gallus 456215 R-GGA-5672011 https://reactome.org/PathwayBrowser/#/R-GGA-5672011 p-AMPK:AMP binds the ULK complex IEA Gallus gallus 456215 R-GGA-5673768 https://reactome.org/PathwayBrowser/#/R-GGA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Gallus gallus 456215 R-GGA-5675868 https://reactome.org/PathwayBrowser/#/R-GGA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Gallus gallus 456215 R-GGA-5679205 https://reactome.org/PathwayBrowser/#/R-GGA-5679205 ULK1 phosphorylates Beclin-1 IEA Gallus gallus 456215 R-GGA-5679239 https://reactome.org/PathwayBrowser/#/R-GGA-5679239 ULK complex translocates to the ER IEA Gallus gallus 456215 R-GGA-5694494 https://reactome.org/PathwayBrowser/#/R-GGA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Gallus gallus 456215 R-GGA-5695957 https://reactome.org/PathwayBrowser/#/R-GGA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Gallus gallus 456215 R-GGA-5696004 https://reactome.org/PathwayBrowser/#/R-GGA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Gallus gallus 456215 R-GGA-5696021 https://reactome.org/PathwayBrowser/#/R-GGA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Gallus gallus 456215 R-GGA-5696049 https://reactome.org/PathwayBrowser/#/R-GGA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 456215 R-GGA-6788798 https://reactome.org/PathwayBrowser/#/R-GGA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 456215 R-GGA-6788810 https://reactome.org/PathwayBrowser/#/R-GGA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 456215 R-GGA-6809287 https://reactome.org/PathwayBrowser/#/R-GGA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Gallus gallus 456215 R-GGA-70467 https://reactome.org/PathwayBrowser/#/R-GGA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Gallus gallus 456215 R-GGA-70479 https://reactome.org/PathwayBrowser/#/R-GGA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Gallus gallus 456215 R-GGA-70577 https://reactome.org/PathwayBrowser/#/R-GGA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Gallus gallus 456215 R-GGA-70599 https://reactome.org/PathwayBrowser/#/R-GGA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Gallus gallus 456215 R-GGA-71735 https://reactome.org/PathwayBrowser/#/R-GGA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Gallus gallus 456215 R-GGA-73580 https://reactome.org/PathwayBrowser/#/R-GGA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Gallus gallus 456215 R-GGA-73792 https://reactome.org/PathwayBrowser/#/R-GGA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Gallus gallus 456215 R-GGA-73828 https://reactome.org/PathwayBrowser/#/R-GGA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Gallus gallus 456215 R-GGA-74213 https://reactome.org/PathwayBrowser/#/R-GGA-74213 APRT catalyzes the conversion of adenine to AMP IEA Gallus gallus 456215 R-GGA-74220 https://reactome.org/PathwayBrowser/#/R-GGA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Gallus gallus 456215 R-GGA-76590 https://reactome.org/PathwayBrowser/#/R-GGA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Gallus gallus 456215 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 456215 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 456215 R-GGA-8852133 https://reactome.org/PathwayBrowser/#/R-GGA-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Gallus gallus 456215 R-GGA-8852136 https://reactome.org/PathwayBrowser/#/R-GGA-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Gallus gallus 456215 R-GGA-8875071 https://reactome.org/PathwayBrowser/#/R-GGA-8875071 ACSS3 ligates CoA to CH3COO- IEA Gallus gallus 456215 R-GGA-8951648 https://reactome.org/PathwayBrowser/#/R-GGA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Gallus gallus 456215 R-GGA-8951656 https://reactome.org/PathwayBrowser/#/R-GGA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Gallus gallus 456215 R-GGA-9009950 https://reactome.org/PathwayBrowser/#/R-GGA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Gallus gallus 456215 R-GGA-947531 https://reactome.org/PathwayBrowser/#/R-GGA-947531 Molybdenum ion transfer onto molybdopterin IEA Gallus gallus 456215 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus 456215 R-GGA-9629675 https://reactome.org/PathwayBrowser/#/R-GGA-9629675 PDE3A hydrolyses cAMP to AMP IEA Gallus gallus 456215 R-GGA-9644869 https://reactome.org/PathwayBrowser/#/R-GGA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Gallus gallus 456215 R-GGA-9705507 https://reactome.org/PathwayBrowser/#/R-GGA-9705507 PDE3B hydrolyses cAMP to AMP IEA Gallus gallus 456215 R-GGA-9734535 https://reactome.org/PathwayBrowser/#/R-GGA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Gallus gallus 456215 R-GGA-9748957 https://reactome.org/PathwayBrowser/#/R-GGA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Gallus gallus 456215 R-GGA-9749971 https://reactome.org/PathwayBrowser/#/R-GGA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Gallus gallus 456215 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus 456215 R-GGA-983153 https://reactome.org/PathwayBrowser/#/R-GGA-983153 E1 mediated ubiquitin activation IEA Gallus gallus 456215 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus 456215 R-HSA-1008248 https://reactome.org/PathwayBrowser/#/R-HSA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase TAS Homo sapiens 456215 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 456215 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 456215 R-HSA-109415 https://reactome.org/PathwayBrowser/#/R-HSA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] TAS Homo sapiens 456215 R-HSA-109624 https://reactome.org/PathwayBrowser/#/R-HSA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) TAS Homo sapiens 456215 R-HSA-110137 https://reactome.org/PathwayBrowser/#/R-HSA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP TAS Homo sapiens 456215 R-HSA-110138 https://reactome.org/PathwayBrowser/#/R-HSA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 456215 R-HSA-110141 https://reactome.org/PathwayBrowser/#/R-HSA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) TAS Homo sapiens 456215 R-HSA-110144 https://reactome.org/PathwayBrowser/#/R-HSA-110144 ADP + ADP <=> AMP + ATP [AK2] TAS Homo sapiens 456215 R-HSA-110145 https://reactome.org/PathwayBrowser/#/R-HSA-110145 AMP + ATP <=> ADP + ADP [AK2] TAS Homo sapiens 456215 R-HSA-111285 https://reactome.org/PathwayBrowser/#/R-HSA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer TAS Homo sapiens 456215 R-HSA-111955 https://reactome.org/PathwayBrowser/#/R-HSA-111955 cAMP hydrolysis by Cam-PDE 1 TAS Homo sapiens 456215 R-HSA-111962 https://reactome.org/PathwayBrowser/#/R-HSA-111962 PDE4A,C,D hydrolyse cAMP TAS Homo sapiens 456215 R-HSA-1169394 https://reactome.org/PathwayBrowser/#/R-HSA-1169394 ISGylation of IRF3 TAS Homo sapiens 456215 R-HSA-1169395 https://reactome.org/PathwayBrowser/#/R-HSA-1169395 ISGylation of viral protein NS1 TAS Homo sapiens 456215 R-HSA-1169397 https://reactome.org/PathwayBrowser/#/R-HSA-1169397 Activation of ISG15 by UBA7 E1 ligase TAS Homo sapiens 456215 R-HSA-1169398 https://reactome.org/PathwayBrowser/#/R-HSA-1169398 ISGylation of host protein filamin B TAS Homo sapiens 456215 R-HSA-1169402 https://reactome.org/PathwayBrowser/#/R-HSA-1169402 ISGylation of E2 conjugating enzymes TAS Homo sapiens 456215 R-HSA-1169405 https://reactome.org/PathwayBrowser/#/R-HSA-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) TAS Homo sapiens 456215 R-HSA-1169406 https://reactome.org/PathwayBrowser/#/R-HSA-1169406 ISGylation of host proteins TAS Homo sapiens 456215 R-HSA-1454699 https://reactome.org/PathwayBrowser/#/R-HSA-1454699 AMPK-alpha2 phosphorylates TBC1D1 IEA Homo sapiens 456215 R-HSA-1592244 https://reactome.org/PathwayBrowser/#/R-HSA-1592244 AMPK phosphorylates PPARGC1A IEA Homo sapiens 456215 R-HSA-159425 https://reactome.org/PathwayBrowser/#/R-HSA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 456215 R-HSA-159443 https://reactome.org/PathwayBrowser/#/R-HSA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-159567 https://reactome.org/PathwayBrowser/#/R-HSA-159567 ACSM2B-like proteins transform ST to ST-CoA TAS Homo sapiens 456215 R-HSA-162425 https://reactome.org/PathwayBrowser/#/R-HSA-162425 p-S295-PDE3B hydrolyses cAMP to AMP TAS Homo sapiens 456215 R-HSA-1632857 https://reactome.org/PathwayBrowser/#/R-HSA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex TAS Homo sapiens 456215 R-HSA-163664 https://reactome.org/PathwayBrowser/#/R-HSA-163664 AMP binds to gamma subunit of AMP kinase heterotrimer TAS Homo sapiens 456215 R-HSA-163691 https://reactome.org/PathwayBrowser/#/R-HSA-163691 Phosphorylation of ChREBP at Serine 556 by AMPK IEA Homo sapiens 456215 R-HSA-164151 https://reactome.org/PathwayBrowser/#/R-HSA-164151 LKB1 phosphorylates the alpha subunit of AMPK heterotrimer IEA Homo sapiens 456215 R-HSA-169260 https://reactome.org/PathwayBrowser/#/R-HSA-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF TAS Homo sapiens 456215 R-HSA-169270 https://reactome.org/PathwayBrowser/#/R-HSA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 TAS Homo sapiens 456215 R-HSA-174441 https://reactome.org/PathwayBrowser/#/R-HSA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand TAS Homo sapiens 456215 R-HSA-176606 https://reactome.org/PathwayBrowser/#/R-HSA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate TAS Homo sapiens 456215 R-HSA-177157 https://reactome.org/PathwayBrowser/#/R-HSA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-192137 https://reactome.org/PathwayBrowser/#/R-HSA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 456215 R-HSA-193401 https://reactome.org/PathwayBrowser/#/R-HSA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 456215 R-HSA-193407 https://reactome.org/PathwayBrowser/#/R-HSA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 456215 R-HSA-193424 https://reactome.org/PathwayBrowser/#/R-HSA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 456215 R-HSA-193711 https://reactome.org/PathwayBrowser/#/R-HSA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 456215 R-HSA-193727 https://reactome.org/PathwayBrowser/#/R-HSA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 456215 R-HSA-193743 https://reactome.org/PathwayBrowser/#/R-HSA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 456215 R-HSA-193766 https://reactome.org/PathwayBrowser/#/R-HSA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 456215 R-HSA-196753 https://reactome.org/PathwayBrowser/#/R-HSA-196753 2xPPCS ligates PPanK with Cys TAS Homo sapiens 456215 R-HSA-196761 https://reactome.org/PathwayBrowser/#/R-HSA-196761 2xTPK1:Mg2+ phosphorylates THMN TAS Homo sapiens 456215 R-HSA-196955 https://reactome.org/PathwayBrowser/#/R-HSA-196955 2xENPP1 hydrolyzes FAD to FMN TAS Homo sapiens 456215 R-HSA-197271 https://reactome.org/PathwayBrowser/#/R-HSA-197271 NADSYN1 hexamer amidates NAAD to NAD+ TAS Homo sapiens 456215 R-HSA-200421 https://reactome.org/PathwayBrowser/#/R-HSA-200421 Activation of cytosolic AMPK by phosphorylation TAS Homo sapiens 456215 R-HSA-201035 https://reactome.org/PathwayBrowser/#/R-HSA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA TAS Homo sapiens 456215 R-HSA-2046085 https://reactome.org/PathwayBrowser/#/R-HSA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA TAS Homo sapiens 456215 R-HSA-2046098 https://reactome.org/PathwayBrowser/#/R-HSA-2046098 Activation of linoleic acid to linoleoyl-CoA TAS Homo sapiens 456215 R-HSA-2161193 https://reactome.org/PathwayBrowser/#/R-HSA-2161193 abacavir + AMP => abacavir monophosphate + adenosine TAS Homo sapiens 456215 R-HSA-2393939 https://reactome.org/PathwayBrowser/#/R-HSA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 456215 R-HSA-2393954 https://reactome.org/PathwayBrowser/#/R-HSA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 456215 R-HSA-2408526 https://reactome.org/PathwayBrowser/#/R-HSA-2408526 tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer TAS Homo sapiens 456215 R-HSA-2408546 https://reactome.org/PathwayBrowser/#/R-HSA-2408546 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex IEA Homo sapiens 456215 R-HSA-2730904 https://reactome.org/PathwayBrowser/#/R-HSA-2730904 Auto-ubiquitination of TRAF6 TAS Homo sapiens 456215 R-HSA-2990833 https://reactome.org/PathwayBrowser/#/R-HSA-2990833 Conjugation of SUMO1 to UBA2:SAE1 TAS Homo sapiens 456215 R-HSA-2993447 https://reactome.org/PathwayBrowser/#/R-HSA-2993447 HLCS biotinylates 6x(PCCA:PCCB) TAS Homo sapiens 456215 R-HSA-2993781 https://reactome.org/PathwayBrowser/#/R-HSA-2993781 Conjugation of SUMO3 to UBA2:SAE1 IEA Homo sapiens 456215 R-HSA-2993784 https://reactome.org/PathwayBrowser/#/R-HSA-2993784 Conjugation of SUMO2 to UBA2:SAE1 IEA Homo sapiens 456215 R-HSA-2993799 https://reactome.org/PathwayBrowser/#/R-HSA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 TAS Homo sapiens 456215 R-HSA-2993802 https://reactome.org/PathwayBrowser/#/R-HSA-2993802 HLCS biotinylates PC:Mn2+ TAS Homo sapiens 456215 R-HSA-2993814 https://reactome.org/PathwayBrowser/#/R-HSA-2993814 HLCS biotinylates ACACA:Mn2+ TAS Homo sapiens 456215 R-HSA-379844 https://reactome.org/PathwayBrowser/#/R-HSA-379844 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379848 https://reactome.org/PathwayBrowser/#/R-HSA-379848 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379861 https://reactome.org/PathwayBrowser/#/R-HSA-379861 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379864 https://reactome.org/PathwayBrowser/#/R-HSA-379864 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379865 https://reactome.org/PathwayBrowser/#/R-HSA-379865 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379867 https://reactome.org/PathwayBrowser/#/R-HSA-379867 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379887 https://reactome.org/PathwayBrowser/#/R-HSA-379887 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379893 https://reactome.org/PathwayBrowser/#/R-HSA-379893 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379974 https://reactome.org/PathwayBrowser/#/R-HSA-379974 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379977 https://reactome.org/PathwayBrowser/#/R-HSA-379977 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379980 https://reactome.org/PathwayBrowser/#/R-HSA-379980 tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379982 https://reactome.org/PathwayBrowser/#/R-HSA-379982 glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379992 https://reactome.org/PathwayBrowser/#/R-HSA-379992 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379993 https://reactome.org/PathwayBrowser/#/R-HSA-379993 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379994 https://reactome.org/PathwayBrowser/#/R-HSA-379994 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-379996 https://reactome.org/PathwayBrowser/#/R-HSA-379996 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380002 https://reactome.org/PathwayBrowser/#/R-HSA-380002 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380008 https://reactome.org/PathwayBrowser/#/R-HSA-380008 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380042 https://reactome.org/PathwayBrowser/#/R-HSA-380042 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380048 https://reactome.org/PathwayBrowser/#/R-HSA-380048 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380157 https://reactome.org/PathwayBrowser/#/R-HSA-380157 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380158 https://reactome.org/PathwayBrowser/#/R-HSA-380158 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate IEA Homo sapiens 456215 R-HSA-380170 https://reactome.org/PathwayBrowser/#/R-HSA-380170 tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380176 https://reactome.org/PathwayBrowser/#/R-HSA-380176 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380177 https://reactome.org/PathwayBrowser/#/R-HSA-380177 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate IEA Homo sapiens 456215 R-HSA-380198 https://reactome.org/PathwayBrowser/#/R-HSA-380198 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate IEA Homo sapiens 456215 R-HSA-380199 https://reactome.org/PathwayBrowser/#/R-HSA-380199 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate IEA Homo sapiens 456215 R-HSA-380200 https://reactome.org/PathwayBrowser/#/R-HSA-380200 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380201 https://reactome.org/PathwayBrowser/#/R-HSA-380201 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate IEA Homo sapiens 456215 R-HSA-380203 https://reactome.org/PathwayBrowser/#/R-HSA-380203 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380216 https://reactome.org/PathwayBrowser/#/R-HSA-380216 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate IEA Homo sapiens 456215 R-HSA-380222 https://reactome.org/PathwayBrowser/#/R-HSA-380222 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380224 https://reactome.org/PathwayBrowser/#/R-HSA-380224 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380227 https://reactome.org/PathwayBrowser/#/R-HSA-380227 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate IEA Homo sapiens 456215 R-HSA-380229 https://reactome.org/PathwayBrowser/#/R-HSA-380229 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380233 https://reactome.org/PathwayBrowser/#/R-HSA-380233 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380234 https://reactome.org/PathwayBrowser/#/R-HSA-380234 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380239 https://reactome.org/PathwayBrowser/#/R-HSA-380239 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380240 https://reactome.org/PathwayBrowser/#/R-HSA-380240 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380241 https://reactome.org/PathwayBrowser/#/R-HSA-380241 glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-380927 https://reactome.org/PathwayBrowser/#/R-HSA-380927 p-AMPK phosphorylates TSC1:TSC2 TAS Homo sapiens 456215 R-HSA-380930 https://reactome.org/PathwayBrowser/#/R-HSA-380930 Phosphorylated AMPK binds AMP TAS Homo sapiens 456215 R-HSA-389622 https://reactome.org/PathwayBrowser/#/R-HSA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-389632 https://reactome.org/PathwayBrowser/#/R-HSA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-389652 https://reactome.org/PathwayBrowser/#/R-HSA-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP TAS Homo sapiens 456215 R-HSA-4167511 https://reactome.org/PathwayBrowser/#/R-HSA-4167511 HLCS biotinylates ACACB TAS Homo sapiens 456215 R-HSA-418553 https://reactome.org/PathwayBrowser/#/R-HSA-418553 cAMP degradation by Phosphodiesterases TAS Homo sapiens 456215 R-HSA-429845 https://reactome.org/PathwayBrowser/#/R-HSA-429845 5' to 3' exoribonuclease hydrolyzes decapped mRNA IEA Homo sapiens 456215 R-HSA-429955 https://reactome.org/PathwayBrowser/#/R-HSA-429955 CCR4-NOT complex deadenylates mRNA TAS Homo sapiens 456215 R-HSA-429992 https://reactome.org/PathwayBrowser/#/R-HSA-429992 PARN deadenylates mRNA TAS Homo sapiens 456215 R-HSA-430021 https://reactome.org/PathwayBrowser/#/R-HSA-430021 PAN2-PAN3 complex partially deadenylates mRNA TAS Homo sapiens 456215 R-HSA-430028 https://reactome.org/PathwayBrowser/#/R-HSA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion TAS Homo sapiens 456215 R-HSA-434382 https://reactome.org/PathwayBrowser/#/R-HSA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell TAS Homo sapiens 456215 R-HSA-447074 https://reactome.org/PathwayBrowser/#/R-HSA-447074 AMPK phosphorylates Raptor in the mTORC1 complex TAS Homo sapiens 456215 R-HSA-449911 https://reactome.org/PathwayBrowser/#/R-HSA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] TAS Homo sapiens 456215 R-HSA-453338 https://reactome.org/PathwayBrowser/#/R-HSA-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP TAS Homo sapiens 456215 R-HSA-453342 https://reactome.org/PathwayBrowser/#/R-HSA-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex TAS Homo sapiens 456215 R-HSA-453346 https://reactome.org/PathwayBrowser/#/R-HSA-453346 PYGB b dimer:AMP complex <=> PGYB dimer, b form + 2 AMP IEA Homo sapiens 456215 R-HSA-453356 https://reactome.org/PathwayBrowser/#/R-HSA-453356 PYGB dimer, b form + 2 AMP <=> PYGB b dimer:AMP complex IEA Homo sapiens 456215 R-HSA-453358 https://reactome.org/PathwayBrowser/#/R-HSA-453358 poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] IEA Homo sapiens 456215 R-HSA-5358475 https://reactome.org/PathwayBrowser/#/R-HSA-5358475 DPH6 ligates ammonium to diphthine-EEF2 TAS Homo sapiens 456215 R-HSA-5358592 https://reactome.org/PathwayBrowser/#/R-HSA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA TAS Homo sapiens 456215 R-HSA-548843 https://reactome.org/PathwayBrowser/#/R-HSA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA TAS Homo sapiens 456215 R-HSA-5607756 https://reactome.org/PathwayBrowser/#/R-HSA-5607756 TRAF6 oligomer autoubiquitinates TAS Homo sapiens 456215 R-HSA-5607757 https://reactome.org/PathwayBrowser/#/R-HSA-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 TAS Homo sapiens 456215 R-HSA-5631941 https://reactome.org/PathwayBrowser/#/R-HSA-5631941 SESN1,2,3 bind AMPK TAS Homo sapiens 456215 R-HSA-5665868 https://reactome.org/PathwayBrowser/#/R-HSA-5665868 AMPK (complex) phosphorylates ULK1 (complex) TAS Homo sapiens 456215 R-HSA-5672008 https://reactome.org/PathwayBrowser/#/R-HSA-5672008 Thr-180 of ULK1 is phosphorylated TAS Homo sapiens 456215 R-HSA-5672011 https://reactome.org/PathwayBrowser/#/R-HSA-5672011 p-AMPK:AMP binds the ULK complex TAS Homo sapiens 456215 R-HSA-5673768 https://reactome.org/PathwayBrowser/#/R-HSA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex TAS Homo sapiens 456215 R-HSA-5675868 https://reactome.org/PathwayBrowser/#/R-HSA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 TAS Homo sapiens 456215 R-HSA-5679205 https://reactome.org/PathwayBrowser/#/R-HSA-5679205 ULK1 phosphorylates Beclin-1 TAS Homo sapiens 456215 R-HSA-5679239 https://reactome.org/PathwayBrowser/#/R-HSA-5679239 ULK complex translocates to the ER TAS Homo sapiens 456215 R-HSA-5694494 https://reactome.org/PathwayBrowser/#/R-HSA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA TAS Homo sapiens 456215 R-HSA-5695957 https://reactome.org/PathwayBrowser/#/R-HSA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA TAS Homo sapiens 456215 R-HSA-5696004 https://reactome.org/PathwayBrowser/#/R-HSA-5696004 ACSF2 ligates CoA-SH to MCFA TAS Homo sapiens 456215 R-HSA-5696007 https://reactome.org/PathwayBrowser/#/R-HSA-5696007 ACSF3 ligates CoA-SH to VLCFA TAS Homo sapiens 456215 R-HSA-5696021 https://reactome.org/PathwayBrowser/#/R-HSA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P TAS Homo sapiens 456215 R-HSA-5696049 https://reactome.org/PathwayBrowser/#/R-HSA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 456215 R-HSA-5696816 https://reactome.org/PathwayBrowser/#/R-HSA-5696816 tRNA ligase complex ligates tRNA exons TAS Homo sapiens 456215 R-HSA-6784494 https://reactome.org/PathwayBrowser/#/R-HSA-6784494 EKC complex threonylcarbamoylates A37 of tRNAs IEA Homo sapiens 456215 R-HSA-6788798 https://reactome.org/PathwayBrowser/#/R-HSA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 456215 R-HSA-6788810 https://reactome.org/PathwayBrowser/#/R-HSA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 456215 R-HSA-6805470 https://reactome.org/PathwayBrowser/#/R-HSA-6805470 AMPK phosphorylates TP53 TAS Homo sapiens 456215 R-HSA-6809287 https://reactome.org/PathwayBrowser/#/R-HSA-6809287 NUDT12 hydrolyses NADH to NMNH TAS Homo sapiens 456215 R-HSA-69144 https://reactome.org/PathwayBrowser/#/R-HSA-69144 Removal of RNA primer and dissociation of RPA and Dna2 TAS Homo sapiens 456215 R-HSA-70467 https://reactome.org/PathwayBrowser/#/R-HSA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP TAS Homo sapiens 456215 R-HSA-70479 https://reactome.org/PathwayBrowser/#/R-HSA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P TAS Homo sapiens 456215 R-HSA-70577 https://reactome.org/PathwayBrowser/#/R-HSA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA TAS Homo sapiens 456215 R-HSA-70599 https://reactome.org/PathwayBrowser/#/R-HSA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] TAS Homo sapiens 456215 R-HSA-71515 https://reactome.org/PathwayBrowser/#/R-HSA-71515 glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] IEA Homo sapiens 456215 R-HSA-71735 https://reactome.org/PathwayBrowser/#/R-HSA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] TAS Homo sapiens 456215 R-HSA-73580 https://reactome.org/PathwayBrowser/#/R-HSA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate TAS Homo sapiens 456215 R-HSA-73792 https://reactome.org/PathwayBrowser/#/R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate TAS Homo sapiens 456215 R-HSA-73828 https://reactome.org/PathwayBrowser/#/R-HSA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate TAS Homo sapiens 456215 R-HSA-74213 https://reactome.org/PathwayBrowser/#/R-HSA-74213 APRT catalyzes the conversion of adenine to AMP TAS Homo sapiens 456215 R-HSA-74220 https://reactome.org/PathwayBrowser/#/R-HSA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) TAS Homo sapiens 456215 R-HSA-76590 https://reactome.org/PathwayBrowser/#/R-HSA-76590 AMP + H2O => IMP + NH4+ (AMPD) TAS Homo sapiens 456215 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 456215 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 456215 R-HSA-8852133 https://reactome.org/PathwayBrowser/#/R-HSA-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol TAS Homo sapiens 456215 R-HSA-8852136 https://reactome.org/PathwayBrowser/#/R-HSA-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus TAS Homo sapiens 456215 R-HSA-8865098 https://reactome.org/PathwayBrowser/#/R-HSA-8865098 UBA6 conjugates ubiquitin to UBA6 in the cytosol IEA Homo sapiens 456215 R-HSA-8875013 https://reactome.org/PathwayBrowser/#/R-HSA-8875013 ACSM3,ACSM6 ligate CoA to BUT IEA Homo sapiens 456215 R-HSA-8875071 https://reactome.org/PathwayBrowser/#/R-HSA-8875071 ACSS3 ligates CoA to CH3COO- TAS Homo sapiens 456215 R-HSA-8875077 https://reactome.org/PathwayBrowser/#/R-HSA-8875077 SLC27A3 ligates CoA-SH to VLCFA IEA Homo sapiens 456215 R-HSA-8951648 https://reactome.org/PathwayBrowser/#/R-HSA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 TAS Homo sapiens 456215 R-HSA-8951656 https://reactome.org/PathwayBrowser/#/R-HSA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 TAS Homo sapiens 456215 R-HSA-8953499 https://reactome.org/PathwayBrowser/#/R-HSA-8953499 IMPAD1 hydrolyses PAP to AMP TAS Homo sapiens 456215 R-HSA-8959510 https://reactome.org/PathwayBrowser/#/R-HSA-8959510 SEPHS2 phosphorylates H2Se to form SELP TAS Homo sapiens 456215 R-HSA-9009950 https://reactome.org/PathwayBrowser/#/R-HSA-9009950 PDE12 cleaves 2'-5' oligoadenylates TAS Homo sapiens 456215 R-HSA-947531 https://reactome.org/PathwayBrowser/#/R-HSA-947531 Molybdenum ion transfer onto molybdopterin TAS Homo sapiens 456215 R-HSA-947538 https://reactome.org/PathwayBrowser/#/R-HSA-947538 Transfer of sulfur from MOCS3-S-S onto MOCS2A TAS Homo sapiens 456215 R-HSA-9613494 https://reactome.org/PathwayBrowser/#/R-HSA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition TAS Homo sapiens 456215 R-HSA-9613530 https://reactome.org/PathwayBrowser/#/R-HSA-9613530 PRKAA2 phosphorylates PLINs IEA Homo sapiens 456215 R-HSA-9615042 https://reactome.org/PathwayBrowser/#/R-HSA-9615042 Viral 2',5'-PDE cleaves 2'-5' oligoadenylates TAS Homo sapiens 456215 R-HSA-9629675 https://reactome.org/PathwayBrowser/#/R-HSA-9629675 PDE3A hydrolyses cAMP to AMP TAS Homo sapiens 456215 R-HSA-9644869 https://reactome.org/PathwayBrowser/#/R-HSA-9644869 p-S54-PDE4B hydrolyses cAMP TAS Homo sapiens 456215 R-HSA-9705507 https://reactome.org/PathwayBrowser/#/R-HSA-9705507 PDE3B hydrolyses cAMP to AMP TAS Homo sapiens 456215 R-HSA-9708261 https://reactome.org/PathwayBrowser/#/R-HSA-9708261 PDE4A hydrolyses cAMP to AMP TAS Homo sapiens 456215 R-HSA-9734535 https://reactome.org/PathwayBrowser/#/R-HSA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA TAS Homo sapiens 456215 R-HSA-9748957 https://reactome.org/PathwayBrowser/#/R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP TAS Homo sapiens 456215 R-HSA-9749971 https://reactome.org/PathwayBrowser/#/R-HSA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA TAS Homo sapiens 456215 R-HSA-9822311 https://reactome.org/PathwayBrowser/#/R-HSA-9822311 CCR4-NOT deadenylates mRNA in CCR4-NOT:BTG4:PABPN1L:mRNP IEA Homo sapiens 456215 R-HSA-9822335 https://reactome.org/PathwayBrowser/#/R-HSA-9822335 CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA IEA Homo sapiens 456215 R-HSA-983140 https://reactome.org/PathwayBrowser/#/R-HSA-983140 Transfer of Ub from E2 to substrate and release of E2 TAS Homo sapiens 456215 R-HSA-983153 https://reactome.org/PathwayBrowser/#/R-HSA-983153 E1 mediated ubiquitin activation TAS Homo sapiens 456215 R-HSA-983156 https://reactome.org/PathwayBrowser/#/R-HSA-983156 Polyubiquitination of substrate TAS Homo sapiens 456215 R-HSA-9833973 https://reactome.org/PathwayBrowser/#/R-HSA-9833973 ISGylation of PKR TAS Homo sapiens 456215 R-HSA-9837231 https://reactome.org/PathwayBrowser/#/R-HSA-9837231 ISGylation of BECN1 TAS Homo sapiens 456215 R-MMU-1008248 https://reactome.org/PathwayBrowser/#/R-MMU-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Mus musculus 456215 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 456215 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 456215 R-MMU-109415 https://reactome.org/PathwayBrowser/#/R-MMU-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Mus musculus 456215 R-MMU-109624 https://reactome.org/PathwayBrowser/#/R-MMU-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Mus musculus 456215 R-MMU-110137 https://reactome.org/PathwayBrowser/#/R-MMU-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Mus musculus 456215 R-MMU-110138 https://reactome.org/PathwayBrowser/#/R-MMU-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 456215 R-MMU-110141 https://reactome.org/PathwayBrowser/#/R-MMU-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Mus musculus 456215 R-MMU-110144 https://reactome.org/PathwayBrowser/#/R-MMU-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Mus musculus 456215 R-MMU-110145 https://reactome.org/PathwayBrowser/#/R-MMU-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Mus musculus 456215 R-MMU-111285 https://reactome.org/PathwayBrowser/#/R-MMU-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Mus musculus 456215 R-MMU-111519 https://reactome.org/PathwayBrowser/#/R-MMU-111519 inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate TAS Mus musculus 456215 R-MMU-111955 https://reactome.org/PathwayBrowser/#/R-MMU-111955 cAMP hydrolysis by Cam-PDE 1 IEA Mus musculus 456215 R-MMU-111962 https://reactome.org/PathwayBrowser/#/R-MMU-111962 PDE4A,C,D hydrolyse cAMP IEA Mus musculus 456215 R-MMU-1169394 https://reactome.org/PathwayBrowser/#/R-MMU-1169394 ISGylation of IRF3 IEA Mus musculus 456215 R-MMU-1169397 https://reactome.org/PathwayBrowser/#/R-MMU-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Mus musculus 456215 R-MMU-1169398 https://reactome.org/PathwayBrowser/#/R-MMU-1169398 ISGylation of host protein filamin B IEA Mus musculus 456215 R-MMU-1169402 https://reactome.org/PathwayBrowser/#/R-MMU-1169402 ISGylation of E2 conjugating enzymes IEA Mus musculus 456215 R-MMU-1169405 https://reactome.org/PathwayBrowser/#/R-MMU-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Mus musculus 456215 R-MMU-1169406 https://reactome.org/PathwayBrowser/#/R-MMU-1169406 ISGylation of host proteins IEA Mus musculus 456215 R-MMU-1454711 https://reactome.org/PathwayBrowser/#/R-MMU-1454711 Ampk-alpha2 Phosphorylates Tbc1d1 TAS Mus musculus 456215 R-MMU-159425 https://reactome.org/PathwayBrowser/#/R-MMU-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 456215 R-MMU-159443 https://reactome.org/PathwayBrowser/#/R-MMU-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Mus musculus 456215 R-MMU-159567 https://reactome.org/PathwayBrowser/#/R-MMU-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Mus musculus 456215 R-MMU-1605475 https://reactome.org/PathwayBrowser/#/R-MMU-1605475 Ampk phosphorylates Ppargc1a TAS Mus musculus 456215 R-MMU-162425 https://reactome.org/PathwayBrowser/#/R-MMU-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Mus musculus 456215 R-MMU-1632857 https://reactome.org/PathwayBrowser/#/R-MMU-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Mus musculus 456215 R-MMU-163664 https://reactome.org/PathwayBrowser/#/R-MMU-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Mus musculus 456215 R-MMU-169260 https://reactome.org/PathwayBrowser/#/R-MMU-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Mus musculus 456215 R-MMU-169270 https://reactome.org/PathwayBrowser/#/R-MMU-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Mus musculus 456215 R-MMU-174441 https://reactome.org/PathwayBrowser/#/R-MMU-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Mus musculus 456215 R-MMU-176606 https://reactome.org/PathwayBrowser/#/R-MMU-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Mus musculus 456215 R-MMU-177157 https://reactome.org/PathwayBrowser/#/R-MMU-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Mus musculus 456215 R-MMU-192137 https://reactome.org/PathwayBrowser/#/R-MMU-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 456215 R-MMU-193401 https://reactome.org/PathwayBrowser/#/R-MMU-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 456215 R-MMU-193407 https://reactome.org/PathwayBrowser/#/R-MMU-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 456215 R-MMU-193424 https://reactome.org/PathwayBrowser/#/R-MMU-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 456215 R-MMU-193711 https://reactome.org/PathwayBrowser/#/R-MMU-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 456215 R-MMU-193727 https://reactome.org/PathwayBrowser/#/R-MMU-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 456215 R-MMU-193743 https://reactome.org/PathwayBrowser/#/R-MMU-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 456215 R-MMU-193766 https://reactome.org/PathwayBrowser/#/R-MMU-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 456215 R-MMU-196753 https://reactome.org/PathwayBrowser/#/R-MMU-196753 2xPPCS ligates PPanK with Cys IEA Mus musculus 456215 R-MMU-196761 https://reactome.org/PathwayBrowser/#/R-MMU-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Mus musculus 456215 R-MMU-196955 https://reactome.org/PathwayBrowser/#/R-MMU-196955 2xENPP1 hydrolyzes FAD to FMN IEA Mus musculus 456215 R-MMU-197271 https://reactome.org/PathwayBrowser/#/R-MMU-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Mus musculus 456215 R-MMU-200421 https://reactome.org/PathwayBrowser/#/R-MMU-200421 Activation of cytosolic AMPK by phosphorylation IEA Mus musculus 456215 R-MMU-201035 https://reactome.org/PathwayBrowser/#/R-MMU-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Mus musculus 456215 R-MMU-2046085 https://reactome.org/PathwayBrowser/#/R-MMU-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Mus musculus 456215 R-MMU-2046098 https://reactome.org/PathwayBrowser/#/R-MMU-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Mus musculus 456215 R-MMU-2393939 https://reactome.org/PathwayBrowser/#/R-MMU-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 456215 R-MMU-2393954 https://reactome.org/PathwayBrowser/#/R-MMU-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 456215 R-MMU-2730904 https://reactome.org/PathwayBrowser/#/R-MMU-2730904 Auto-ubiquitination of TRAF6 IEA Mus musculus 456215 R-MMU-2990833 https://reactome.org/PathwayBrowser/#/R-MMU-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Mus musculus 456215 R-MMU-2993447 https://reactome.org/PathwayBrowser/#/R-MMU-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Mus musculus 456215 R-MMU-2993799 https://reactome.org/PathwayBrowser/#/R-MMU-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Mus musculus 456215 R-MMU-2993802 https://reactome.org/PathwayBrowser/#/R-MMU-2993802 HLCS biotinylates PC:Mn2+ IEA Mus musculus 456215 R-MMU-2993814 https://reactome.org/PathwayBrowser/#/R-MMU-2993814 HLCS biotinylates ACACA:Mn2+ IEA Mus musculus 456215 R-MMU-380927 https://reactome.org/PathwayBrowser/#/R-MMU-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Mus musculus 456215 R-MMU-380930 https://reactome.org/PathwayBrowser/#/R-MMU-380930 Phosphorylated AMPK binds AMP IEA Mus musculus 456215 R-MMU-389622 https://reactome.org/PathwayBrowser/#/R-MMU-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 456215 R-MMU-389632 https://reactome.org/PathwayBrowser/#/R-MMU-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 456215 R-MMU-389652 https://reactome.org/PathwayBrowser/#/R-MMU-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Mus musculus 456215 R-MMU-4167511 https://reactome.org/PathwayBrowser/#/R-MMU-4167511 HLCS biotinylates ACACB IEA Mus musculus 456215 R-MMU-418553 https://reactome.org/PathwayBrowser/#/R-MMU-418553 cAMP degradation by Phosphodiesterases IEA Mus musculus 456215 R-MMU-429955 https://reactome.org/PathwayBrowser/#/R-MMU-429955 CCR4-NOT complex deadenylates mRNA IEA Mus musculus 456215 R-MMU-429992 https://reactome.org/PathwayBrowser/#/R-MMU-429992 PARN deadenylates mRNA IEA Mus musculus 456215 R-MMU-430021 https://reactome.org/PathwayBrowser/#/R-MMU-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Mus musculus 456215 R-MMU-430028 https://reactome.org/PathwayBrowser/#/R-MMU-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Mus musculus 456215 R-MMU-434382 https://reactome.org/PathwayBrowser/#/R-MMU-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Mus musculus 456215 R-MMU-447074 https://reactome.org/PathwayBrowser/#/R-MMU-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Mus musculus 456215 R-MMU-449911 https://reactome.org/PathwayBrowser/#/R-MMU-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Mus musculus 456215 R-MMU-453338 https://reactome.org/PathwayBrowser/#/R-MMU-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP IEA Mus musculus 456215 R-MMU-453342 https://reactome.org/PathwayBrowser/#/R-MMU-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Mus musculus 456215 R-MMU-5358475 https://reactome.org/PathwayBrowser/#/R-MMU-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Mus musculus 456215 R-MMU-5358592 https://reactome.org/PathwayBrowser/#/R-MMU-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Mus musculus 456215 R-MMU-548843 https://reactome.org/PathwayBrowser/#/R-MMU-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Mus musculus 456215 R-MMU-5607756 https://reactome.org/PathwayBrowser/#/R-MMU-5607756 TRAF6 oligomer autoubiquitinates IEA Mus musculus 456215 R-MMU-5607757 https://reactome.org/PathwayBrowser/#/R-MMU-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 IEA Mus musculus 456215 R-MMU-5631941 https://reactome.org/PathwayBrowser/#/R-MMU-5631941 SESN1,2,3 bind AMPK IEA Mus musculus 456215 R-MMU-5665868 https://reactome.org/PathwayBrowser/#/R-MMU-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Mus musculus 456215 R-MMU-5672008 https://reactome.org/PathwayBrowser/#/R-MMU-5672008 Thr-180 of ULK1 is phosphorylated IEA Mus musculus 456215 R-MMU-5672011 https://reactome.org/PathwayBrowser/#/R-MMU-5672011 p-AMPK:AMP binds the ULK complex IEA Mus musculus 456215 R-MMU-5673768 https://reactome.org/PathwayBrowser/#/R-MMU-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Mus musculus 456215 R-MMU-5675868 https://reactome.org/PathwayBrowser/#/R-MMU-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Mus musculus 456215 R-MMU-5679205 https://reactome.org/PathwayBrowser/#/R-MMU-5679205 ULK1 phosphorylates Beclin-1 IEA Mus musculus 456215 R-MMU-5679239 https://reactome.org/PathwayBrowser/#/R-MMU-5679239 ULK complex translocates to the ER IEA Mus musculus 456215 R-MMU-5694494 https://reactome.org/PathwayBrowser/#/R-MMU-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Mus musculus 456215 R-MMU-5695957 https://reactome.org/PathwayBrowser/#/R-MMU-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Mus musculus 456215 R-MMU-5696004 https://reactome.org/PathwayBrowser/#/R-MMU-5696004 ACSF2 ligates CoA-SH to MCFA IEA Mus musculus 456215 R-MMU-5696007 https://reactome.org/PathwayBrowser/#/R-MMU-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Mus musculus 456215 R-MMU-5696021 https://reactome.org/PathwayBrowser/#/R-MMU-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Mus musculus 456215 R-MMU-5696049 https://reactome.org/PathwayBrowser/#/R-MMU-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 456215 R-MMU-6788798 https://reactome.org/PathwayBrowser/#/R-MMU-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 456215 R-MMU-6788810 https://reactome.org/PathwayBrowser/#/R-MMU-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 456215 R-MMU-6805470 https://reactome.org/PathwayBrowser/#/R-MMU-6805470 AMPK phosphorylates TP53 IEA Mus musculus 456215 R-MMU-6809287 https://reactome.org/PathwayBrowser/#/R-MMU-6809287 NUDT12 hydrolyses NADH to NMNH IEA Mus musculus 456215 R-MMU-69144 https://reactome.org/PathwayBrowser/#/R-MMU-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Mus musculus 456215 R-MMU-70467 https://reactome.org/PathwayBrowser/#/R-MMU-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Mus musculus 456215 R-MMU-70479 https://reactome.org/PathwayBrowser/#/R-MMU-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Mus musculus 456215 R-MMU-70577 https://reactome.org/PathwayBrowser/#/R-MMU-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Mus musculus 456215 R-MMU-70599 https://reactome.org/PathwayBrowser/#/R-MMU-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Mus musculus 456215 R-MMU-71735 https://reactome.org/PathwayBrowser/#/R-MMU-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Mus musculus 456215 R-MMU-73580 https://reactome.org/PathwayBrowser/#/R-MMU-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Mus musculus 456215 R-MMU-73792 https://reactome.org/PathwayBrowser/#/R-MMU-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Mus musculus 456215 R-MMU-73828 https://reactome.org/PathwayBrowser/#/R-MMU-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Mus musculus 456215 R-MMU-74213 https://reactome.org/PathwayBrowser/#/R-MMU-74213 APRT catalyzes the conversion of adenine to AMP IEA Mus musculus 456215 R-MMU-74220 https://reactome.org/PathwayBrowser/#/R-MMU-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Mus musculus 456215 R-MMU-76590 https://reactome.org/PathwayBrowser/#/R-MMU-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Mus musculus 456215 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 456215 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 456215 R-MMU-8852133 https://reactome.org/PathwayBrowser/#/R-MMU-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Mus musculus 456215 R-MMU-8852136 https://reactome.org/PathwayBrowser/#/R-MMU-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Mus musculus 456215 R-MMU-8875039 https://reactome.org/PathwayBrowser/#/R-MMU-8875039 Acsm3 ligates CoA to BUT TAS Mus musculus 456215 R-MMU-8875071 https://reactome.org/PathwayBrowser/#/R-MMU-8875071 ACSS3 ligates CoA to CH3COO- IEA Mus musculus 456215 R-MMU-8875095 https://reactome.org/PathwayBrowser/#/R-MMU-8875095 Slc27a3 ligates CoA to VLCFA TAS Mus musculus 456215 R-MMU-8951648 https://reactome.org/PathwayBrowser/#/R-MMU-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Mus musculus 456215 R-MMU-8951656 https://reactome.org/PathwayBrowser/#/R-MMU-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Mus musculus 456215 R-MMU-8953499 https://reactome.org/PathwayBrowser/#/R-MMU-8953499 IMPAD1 hydrolyses PAP to AMP IEA Mus musculus 456215 R-MMU-8959510 https://reactome.org/PathwayBrowser/#/R-MMU-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Mus musculus 456215 R-MMU-9009950 https://reactome.org/PathwayBrowser/#/R-MMU-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Mus musculus 456215 R-MMU-947531 https://reactome.org/PathwayBrowser/#/R-MMU-947531 Molybdenum ion transfer onto molybdopterin IEA Mus musculus 456215 R-MMU-9613494 https://reactome.org/PathwayBrowser/#/R-MMU-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Mus musculus 456215 R-MMU-9613545 https://reactome.org/PathwayBrowser/#/R-MMU-9613545 Prkaa2 phosphorylates Plins TAS Mus musculus 456215 R-MMU-9629675 https://reactome.org/PathwayBrowser/#/R-MMU-9629675 PDE3A hydrolyses cAMP to AMP IEA Mus musculus 456215 R-MMU-9644869 https://reactome.org/PathwayBrowser/#/R-MMU-9644869 p-S54-PDE4B hydrolyses cAMP IEA Mus musculus 456215 R-MMU-9705507 https://reactome.org/PathwayBrowser/#/R-MMU-9705507 PDE3B hydrolyses cAMP to AMP IEA Mus musculus 456215 R-MMU-9708261 https://reactome.org/PathwayBrowser/#/R-MMU-9708261 PDE4A hydrolyses cAMP to AMP IEA Mus musculus 456215 R-MMU-9734535 https://reactome.org/PathwayBrowser/#/R-MMU-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Mus musculus 456215 R-MMU-9748957 https://reactome.org/PathwayBrowser/#/R-MMU-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Mus musculus 456215 R-MMU-9749971 https://reactome.org/PathwayBrowser/#/R-MMU-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Mus musculus 456215 R-MMU-9822325 https://reactome.org/PathwayBrowser/#/R-MMU-9822325 CCR4-NOT deadenylates mRNA in CCR4-NOT:Btg4:Pabpn1l:mRNP TAS Mus musculus 456215 R-MMU-9822332 https://reactome.org/PathwayBrowser/#/R-MMU-9822332 CCR4-NOT(Cnot6l) deadenylates mRNA in CCR4-NOT(Cnot6l):Zfp36l2:mRNA TAS Mus musculus 456215 R-MMU-983140 https://reactome.org/PathwayBrowser/#/R-MMU-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Mus musculus 456215 R-MMU-983153 https://reactome.org/PathwayBrowser/#/R-MMU-983153 E1 mediated ubiquitin activation IEA Mus musculus 456215 R-MMU-983156 https://reactome.org/PathwayBrowser/#/R-MMU-983156 Polyubiquitination of substrate IEA Mus musculus 456215 R-MMU-9833973 https://reactome.org/PathwayBrowser/#/R-MMU-9833973 ISGylation of PKR IEA Mus musculus 456215 R-MTU-879319 https://reactome.org/PathwayBrowser/#/R-MTU-879319 glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol TAS Mycobacterium tuberculosis 456215 R-MTU-936655 https://reactome.org/PathwayBrowser/#/R-MTU-936655 sulfite results from reduction of APS TAS Mycobacterium tuberculosis 456215 R-MTU-9635428 https://reactome.org/PathwayBrowser/#/R-MTU-9635428 FadD26, FadD28 transfer LCFA adenylate ester to Pks5 TAS Mycobacterium tuberculosis 456215 R-PFA-1008248 https://reactome.org/PathwayBrowser/#/R-PFA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Plasmodium falciparum 456215 R-PFA-110137 https://reactome.org/PathwayBrowser/#/R-PFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Plasmodium falciparum 456215 R-PFA-110138 https://reactome.org/PathwayBrowser/#/R-PFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 456215 R-PFA-110144 https://reactome.org/PathwayBrowser/#/R-PFA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Plasmodium falciparum 456215 R-PFA-110145 https://reactome.org/PathwayBrowser/#/R-PFA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Plasmodium falciparum 456215 R-PFA-111955 https://reactome.org/PathwayBrowser/#/R-PFA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Plasmodium falciparum 456215 R-PFA-111962 https://reactome.org/PathwayBrowser/#/R-PFA-111962 PDE4A,C,D hydrolyse cAMP IEA Plasmodium falciparum 456215 R-PFA-1169397 https://reactome.org/PathwayBrowser/#/R-PFA-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Plasmodium falciparum 456215 R-PFA-162425 https://reactome.org/PathwayBrowser/#/R-PFA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Plasmodium falciparum 456215 R-PFA-196753 https://reactome.org/PathwayBrowser/#/R-PFA-196753 2xPPCS ligates PPanK with Cys IEA Plasmodium falciparum 456215 R-PFA-196761 https://reactome.org/PathwayBrowser/#/R-PFA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Plasmodium falciparum 456215 R-PFA-197271 https://reactome.org/PathwayBrowser/#/R-PFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Plasmodium falciparum 456215 R-PFA-201035 https://reactome.org/PathwayBrowser/#/R-PFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Plasmodium falciparum 456215 R-PFA-2046085 https://reactome.org/PathwayBrowser/#/R-PFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Plasmodium falciparum 456215 R-PFA-2046098 https://reactome.org/PathwayBrowser/#/R-PFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Plasmodium falciparum 456215 R-PFA-2993814 https://reactome.org/PathwayBrowser/#/R-PFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Plasmodium falciparum 456215 R-PFA-4167511 https://reactome.org/PathwayBrowser/#/R-PFA-4167511 HLCS biotinylates ACACB IEA Plasmodium falciparum 456215 R-PFA-418553 https://reactome.org/PathwayBrowser/#/R-PFA-418553 cAMP degradation by Phosphodiesterases IEA Plasmodium falciparum 456215 R-PFA-449911 https://reactome.org/PathwayBrowser/#/R-PFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Plasmodium falciparum 456215 R-PFA-5358592 https://reactome.org/PathwayBrowser/#/R-PFA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Plasmodium falciparum 456215 R-PFA-6788798 https://reactome.org/PathwayBrowser/#/R-PFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 456215 R-PFA-6788810 https://reactome.org/PathwayBrowser/#/R-PFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 456215 R-PFA-70599 https://reactome.org/PathwayBrowser/#/R-PFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Plasmodium falciparum 456215 R-PFA-71735 https://reactome.org/PathwayBrowser/#/R-PFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Plasmodium falciparum 456215 R-PFA-73580 https://reactome.org/PathwayBrowser/#/R-PFA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Plasmodium falciparum 456215 R-PFA-73792 https://reactome.org/PathwayBrowser/#/R-PFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Plasmodium falciparum 456215 R-PFA-76590 https://reactome.org/PathwayBrowser/#/R-PFA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Plasmodium falciparum 456215 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 456215 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 456215 R-PFA-8852133 https://reactome.org/PathwayBrowser/#/R-PFA-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Plasmodium falciparum 456215 R-PFA-8852136 https://reactome.org/PathwayBrowser/#/R-PFA-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Plasmodium falciparum 456215 R-PFA-8951648 https://reactome.org/PathwayBrowser/#/R-PFA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Plasmodium falciparum 456215 R-PFA-8951656 https://reactome.org/PathwayBrowser/#/R-PFA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Plasmodium falciparum 456215 R-PFA-8959510 https://reactome.org/PathwayBrowser/#/R-PFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Plasmodium falciparum 456215 R-PFA-9629675 https://reactome.org/PathwayBrowser/#/R-PFA-9629675 PDE3A hydrolyses cAMP to AMP IEA Plasmodium falciparum 456215 R-PFA-9644869 https://reactome.org/PathwayBrowser/#/R-PFA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Plasmodium falciparum 456215 R-PFA-9705507 https://reactome.org/PathwayBrowser/#/R-PFA-9705507 PDE3B hydrolyses cAMP to AMP IEA Plasmodium falciparum 456215 R-PFA-9708261 https://reactome.org/PathwayBrowser/#/R-PFA-9708261 PDE4A hydrolyses cAMP to AMP IEA Plasmodium falciparum 456215 R-PFA-9748957 https://reactome.org/PathwayBrowser/#/R-PFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Plasmodium falciparum 456215 R-PFA-983140 https://reactome.org/PathwayBrowser/#/R-PFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Plasmodium falciparum 456215 R-PFA-983153 https://reactome.org/PathwayBrowser/#/R-PFA-983153 E1 mediated ubiquitin activation IEA Plasmodium falciparum 456215 R-PFA-983156 https://reactome.org/PathwayBrowser/#/R-PFA-983156 Polyubiquitination of substrate IEA Plasmodium falciparum 456215 R-RNO-1008248 https://reactome.org/PathwayBrowser/#/R-RNO-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Rattus norvegicus 456215 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 456215 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 456215 R-RNO-109415 https://reactome.org/PathwayBrowser/#/R-RNO-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Rattus norvegicus 456215 R-RNO-109624 https://reactome.org/PathwayBrowser/#/R-RNO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Rattus norvegicus 456215 R-RNO-110137 https://reactome.org/PathwayBrowser/#/R-RNO-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Rattus norvegicus 456215 R-RNO-110138 https://reactome.org/PathwayBrowser/#/R-RNO-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 456215 R-RNO-110141 https://reactome.org/PathwayBrowser/#/R-RNO-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Rattus norvegicus 456215 R-RNO-110144 https://reactome.org/PathwayBrowser/#/R-RNO-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Rattus norvegicus 456215 R-RNO-110145 https://reactome.org/PathwayBrowser/#/R-RNO-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Rattus norvegicus 456215 R-RNO-111285 https://reactome.org/PathwayBrowser/#/R-RNO-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Rattus norvegicus 456215 R-RNO-111955 https://reactome.org/PathwayBrowser/#/R-RNO-111955 cAMP hydrolysis by Cam-PDE 1 IEA Rattus norvegicus 456215 R-RNO-111962 https://reactome.org/PathwayBrowser/#/R-RNO-111962 PDE4A,C,D hydrolyse cAMP IEA Rattus norvegicus 456215 R-RNO-1169394 https://reactome.org/PathwayBrowser/#/R-RNO-1169394 ISGylation of IRF3 IEA Rattus norvegicus 456215 R-RNO-1169397 https://reactome.org/PathwayBrowser/#/R-RNO-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Rattus norvegicus 456215 R-RNO-1169398 https://reactome.org/PathwayBrowser/#/R-RNO-1169398 ISGylation of host protein filamin B IEA Rattus norvegicus 456215 R-RNO-1169402 https://reactome.org/PathwayBrowser/#/R-RNO-1169402 ISGylation of E2 conjugating enzymes IEA Rattus norvegicus 456215 R-RNO-1169405 https://reactome.org/PathwayBrowser/#/R-RNO-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Rattus norvegicus 456215 R-RNO-1169406 https://reactome.org/PathwayBrowser/#/R-RNO-1169406 ISGylation of host proteins IEA Rattus norvegicus 456215 R-RNO-159425 https://reactome.org/PathwayBrowser/#/R-RNO-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 456215 R-RNO-159443 https://reactome.org/PathwayBrowser/#/R-RNO-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 456215 R-RNO-159567 https://reactome.org/PathwayBrowser/#/R-RNO-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Rattus norvegicus 456215 R-RNO-162425 https://reactome.org/PathwayBrowser/#/R-RNO-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Rattus norvegicus 456215 R-RNO-1632857 https://reactome.org/PathwayBrowser/#/R-RNO-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Rattus norvegicus 456215 R-RNO-163664 https://reactome.org/PathwayBrowser/#/R-RNO-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Rattus norvegicus 456215 R-RNO-164087 https://reactome.org/PathwayBrowser/#/R-RNO-164087 Phosphorylation of rChREBP(Ser 568) by rAMPK TAS Rattus norvegicus 456215 R-RNO-164106 https://reactome.org/PathwayBrowser/#/R-RNO-164106 rLkb-1 (Stk-11) activates AMPK by phosphorylation TAS Rattus norvegicus 456215 R-RNO-169260 https://reactome.org/PathwayBrowser/#/R-RNO-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Rattus norvegicus 456215 R-RNO-169270 https://reactome.org/PathwayBrowser/#/R-RNO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Rattus norvegicus 456215 R-RNO-174441 https://reactome.org/PathwayBrowser/#/R-RNO-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Rattus norvegicus 456215 R-RNO-176606 https://reactome.org/PathwayBrowser/#/R-RNO-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Rattus norvegicus 456215 R-RNO-177157 https://reactome.org/PathwayBrowser/#/R-RNO-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 456215 R-RNO-192137 https://reactome.org/PathwayBrowser/#/R-RNO-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 456215 R-RNO-193401 https://reactome.org/PathwayBrowser/#/R-RNO-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 456215 R-RNO-193407 https://reactome.org/PathwayBrowser/#/R-RNO-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 456215 R-RNO-193424 https://reactome.org/PathwayBrowser/#/R-RNO-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 456215 R-RNO-193711 https://reactome.org/PathwayBrowser/#/R-RNO-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 456215 R-RNO-193727 https://reactome.org/PathwayBrowser/#/R-RNO-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 456215 R-RNO-193743 https://reactome.org/PathwayBrowser/#/R-RNO-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 456215 R-RNO-193766 https://reactome.org/PathwayBrowser/#/R-RNO-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 456215 R-RNO-196753 https://reactome.org/PathwayBrowser/#/R-RNO-196753 2xPPCS ligates PPanK with Cys IEA Rattus norvegicus 456215 R-RNO-196761 https://reactome.org/PathwayBrowser/#/R-RNO-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Rattus norvegicus 456215 R-RNO-196955 https://reactome.org/PathwayBrowser/#/R-RNO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Rattus norvegicus 456215 R-RNO-197271 https://reactome.org/PathwayBrowser/#/R-RNO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Rattus norvegicus 456215 R-RNO-200421 https://reactome.org/PathwayBrowser/#/R-RNO-200421 Activation of cytosolic AMPK by phosphorylation IEA Rattus norvegicus 456215 R-RNO-201035 https://reactome.org/PathwayBrowser/#/R-RNO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Rattus norvegicus 456215 R-RNO-2046085 https://reactome.org/PathwayBrowser/#/R-RNO-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Rattus norvegicus 456215 R-RNO-2046098 https://reactome.org/PathwayBrowser/#/R-RNO-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Rattus norvegicus 456215 R-RNO-2393939 https://reactome.org/PathwayBrowser/#/R-RNO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 456215 R-RNO-2393954 https://reactome.org/PathwayBrowser/#/R-RNO-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 456215 R-RNO-2990833 https://reactome.org/PathwayBrowser/#/R-RNO-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Rattus norvegicus 456215 R-RNO-2993447 https://reactome.org/PathwayBrowser/#/R-RNO-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Rattus norvegicus 456215 R-RNO-2993799 https://reactome.org/PathwayBrowser/#/R-RNO-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Rattus norvegicus 456215 R-RNO-2993802 https://reactome.org/PathwayBrowser/#/R-RNO-2993802 HLCS biotinylates PC:Mn2+ IEA Rattus norvegicus 456215 R-RNO-2993814 https://reactome.org/PathwayBrowser/#/R-RNO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Rattus norvegicus 456215 R-RNO-380927 https://reactome.org/PathwayBrowser/#/R-RNO-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Rattus norvegicus 456215 R-RNO-380930 https://reactome.org/PathwayBrowser/#/R-RNO-380930 Phosphorylated AMPK binds AMP IEA Rattus norvegicus 456215 R-RNO-389622 https://reactome.org/PathwayBrowser/#/R-RNO-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 456215 R-RNO-389632 https://reactome.org/PathwayBrowser/#/R-RNO-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 456215 R-RNO-4167511 https://reactome.org/PathwayBrowser/#/R-RNO-4167511 HLCS biotinylates ACACB IEA Rattus norvegicus 456215 R-RNO-418553 https://reactome.org/PathwayBrowser/#/R-RNO-418553 cAMP degradation by Phosphodiesterases IEA Rattus norvegicus 456215 R-RNO-430021 https://reactome.org/PathwayBrowser/#/R-RNO-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Rattus norvegicus 456215 R-RNO-430028 https://reactome.org/PathwayBrowser/#/R-RNO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Rattus norvegicus 456215 R-RNO-434382 https://reactome.org/PathwayBrowser/#/R-RNO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Rattus norvegicus 456215 R-RNO-447074 https://reactome.org/PathwayBrowser/#/R-RNO-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Rattus norvegicus 456215 R-RNO-449911 https://reactome.org/PathwayBrowser/#/R-RNO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Rattus norvegicus 456215 R-RNO-453338 https://reactome.org/PathwayBrowser/#/R-RNO-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP IEA Rattus norvegicus 456215 R-RNO-453342 https://reactome.org/PathwayBrowser/#/R-RNO-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Rattus norvegicus 456215 R-RNO-5358475 https://reactome.org/PathwayBrowser/#/R-RNO-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Rattus norvegicus 456215 R-RNO-5358592 https://reactome.org/PathwayBrowser/#/R-RNO-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Rattus norvegicus 456215 R-RNO-548843 https://reactome.org/PathwayBrowser/#/R-RNO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Rattus norvegicus 456215 R-RNO-5631941 https://reactome.org/PathwayBrowser/#/R-RNO-5631941 SESN1,2,3 bind AMPK IEA Rattus norvegicus 456215 R-RNO-5665868 https://reactome.org/PathwayBrowser/#/R-RNO-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Rattus norvegicus 456215 R-RNO-5672008 https://reactome.org/PathwayBrowser/#/R-RNO-5672008 Thr-180 of ULK1 is phosphorylated IEA Rattus norvegicus 456215 R-RNO-5672011 https://reactome.org/PathwayBrowser/#/R-RNO-5672011 p-AMPK:AMP binds the ULK complex IEA Rattus norvegicus 456215 R-RNO-5673768 https://reactome.org/PathwayBrowser/#/R-RNO-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Rattus norvegicus 456215 R-RNO-5675868 https://reactome.org/PathwayBrowser/#/R-RNO-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Rattus norvegicus 456215 R-RNO-5679205 https://reactome.org/PathwayBrowser/#/R-RNO-5679205 ULK1 phosphorylates Beclin-1 IEA Rattus norvegicus 456215 R-RNO-5679239 https://reactome.org/PathwayBrowser/#/R-RNO-5679239 ULK complex translocates to the ER IEA Rattus norvegicus 456215 R-RNO-5694494 https://reactome.org/PathwayBrowser/#/R-RNO-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Rattus norvegicus 456215 R-RNO-5695957 https://reactome.org/PathwayBrowser/#/R-RNO-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Rattus norvegicus 456215 R-RNO-5696004 https://reactome.org/PathwayBrowser/#/R-RNO-5696004 ACSF2 ligates CoA-SH to MCFA IEA Rattus norvegicus 456215 R-RNO-5696007 https://reactome.org/PathwayBrowser/#/R-RNO-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Rattus norvegicus 456215 R-RNO-5696021 https://reactome.org/PathwayBrowser/#/R-RNO-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Rattus norvegicus 456215 R-RNO-5696049 https://reactome.org/PathwayBrowser/#/R-RNO-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 456215 R-RNO-6788798 https://reactome.org/PathwayBrowser/#/R-RNO-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 456215 R-RNO-6788810 https://reactome.org/PathwayBrowser/#/R-RNO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 456215 R-RNO-6805470 https://reactome.org/PathwayBrowser/#/R-RNO-6805470 AMPK phosphorylates TP53 IEA Rattus norvegicus 456215 R-RNO-6809287 https://reactome.org/PathwayBrowser/#/R-RNO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Rattus norvegicus 456215 R-RNO-69144 https://reactome.org/PathwayBrowser/#/R-RNO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Rattus norvegicus 456215 R-RNO-70467 https://reactome.org/PathwayBrowser/#/R-RNO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Rattus norvegicus 456215 R-RNO-70479 https://reactome.org/PathwayBrowser/#/R-RNO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Rattus norvegicus 456215 R-RNO-70599 https://reactome.org/PathwayBrowser/#/R-RNO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Rattus norvegicus 456215 R-RNO-71735 https://reactome.org/PathwayBrowser/#/R-RNO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Rattus norvegicus 456215 R-RNO-73580 https://reactome.org/PathwayBrowser/#/R-RNO-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Rattus norvegicus 456215 R-RNO-73792 https://reactome.org/PathwayBrowser/#/R-RNO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Rattus norvegicus 456215 R-RNO-73828 https://reactome.org/PathwayBrowser/#/R-RNO-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Rattus norvegicus 456215 R-RNO-74213 https://reactome.org/PathwayBrowser/#/R-RNO-74213 APRT catalyzes the conversion of adenine to AMP IEA Rattus norvegicus 456215 R-RNO-74220 https://reactome.org/PathwayBrowser/#/R-RNO-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Rattus norvegicus 456215 R-RNO-76590 https://reactome.org/PathwayBrowser/#/R-RNO-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Rattus norvegicus 456215 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 456215 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 456215 R-RNO-8852133 https://reactome.org/PathwayBrowser/#/R-RNO-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Rattus norvegicus 456215 R-RNO-8852136 https://reactome.org/PathwayBrowser/#/R-RNO-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Rattus norvegicus 456215 R-RNO-8875071 https://reactome.org/PathwayBrowser/#/R-RNO-8875071 ACSS3 ligates CoA to CH3COO- IEA Rattus norvegicus 456215 R-RNO-8951648 https://reactome.org/PathwayBrowser/#/R-RNO-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Rattus norvegicus 456215 R-RNO-8951656 https://reactome.org/PathwayBrowser/#/R-RNO-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Rattus norvegicus 456215 R-RNO-8953499 https://reactome.org/PathwayBrowser/#/R-RNO-8953499 IMPAD1 hydrolyses PAP to AMP IEA Rattus norvegicus 456215 R-RNO-8959510 https://reactome.org/PathwayBrowser/#/R-RNO-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Rattus norvegicus 456215 R-RNO-9009950 https://reactome.org/PathwayBrowser/#/R-RNO-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Rattus norvegicus 456215 R-RNO-947531 https://reactome.org/PathwayBrowser/#/R-RNO-947531 Molybdenum ion transfer onto molybdopterin IEA Rattus norvegicus 456215 R-RNO-9613494 https://reactome.org/PathwayBrowser/#/R-RNO-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Rattus norvegicus 456215 R-RNO-9629675 https://reactome.org/PathwayBrowser/#/R-RNO-9629675 PDE3A hydrolyses cAMP to AMP IEA Rattus norvegicus 456215 R-RNO-9644869 https://reactome.org/PathwayBrowser/#/R-RNO-9644869 p-S54-PDE4B hydrolyses cAMP IEA Rattus norvegicus 456215 R-RNO-9705507 https://reactome.org/PathwayBrowser/#/R-RNO-9705507 PDE3B hydrolyses cAMP to AMP IEA Rattus norvegicus 456215 R-RNO-9708261 https://reactome.org/PathwayBrowser/#/R-RNO-9708261 PDE4A hydrolyses cAMP to AMP IEA Rattus norvegicus 456215 R-RNO-9734535 https://reactome.org/PathwayBrowser/#/R-RNO-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Rattus norvegicus 456215 R-RNO-9748957 https://reactome.org/PathwayBrowser/#/R-RNO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Rattus norvegicus 456215 R-RNO-9749971 https://reactome.org/PathwayBrowser/#/R-RNO-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Rattus norvegicus 456215 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus 456215 R-RNO-983153 https://reactome.org/PathwayBrowser/#/R-RNO-983153 E1 mediated ubiquitin activation IEA Rattus norvegicus 456215 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus 456215 R-RNO-9833973 https://reactome.org/PathwayBrowser/#/R-RNO-9833973 ISGylation of PKR IEA Rattus norvegicus 456215 R-SCE-1008248 https://reactome.org/PathwayBrowser/#/R-SCE-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Saccharomyces cerevisiae 456215 R-SCE-109624 https://reactome.org/PathwayBrowser/#/R-SCE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Saccharomyces cerevisiae 456215 R-SCE-110144 https://reactome.org/PathwayBrowser/#/R-SCE-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Saccharomyces cerevisiae 456215 R-SCE-110145 https://reactome.org/PathwayBrowser/#/R-SCE-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Saccharomyces cerevisiae 456215 R-SCE-159425 https://reactome.org/PathwayBrowser/#/R-SCE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 456215 R-SCE-163664 https://reactome.org/PathwayBrowser/#/R-SCE-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Saccharomyces cerevisiae 456215 R-SCE-169260 https://reactome.org/PathwayBrowser/#/R-SCE-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Saccharomyces cerevisiae 456215 R-SCE-169270 https://reactome.org/PathwayBrowser/#/R-SCE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Saccharomyces cerevisiae 456215 R-SCE-192137 https://reactome.org/PathwayBrowser/#/R-SCE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 456215 R-SCE-193401 https://reactome.org/PathwayBrowser/#/R-SCE-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 456215 R-SCE-193407 https://reactome.org/PathwayBrowser/#/R-SCE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 456215 R-SCE-193424 https://reactome.org/PathwayBrowser/#/R-SCE-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 456215 R-SCE-193711 https://reactome.org/PathwayBrowser/#/R-SCE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 456215 R-SCE-193727 https://reactome.org/PathwayBrowser/#/R-SCE-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 456215 R-SCE-193743 https://reactome.org/PathwayBrowser/#/R-SCE-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 456215 R-SCE-193766 https://reactome.org/PathwayBrowser/#/R-SCE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 456215 R-SCE-196753 https://reactome.org/PathwayBrowser/#/R-SCE-196753 2xPPCS ligates PPanK with Cys IEA Saccharomyces cerevisiae 456215 R-SCE-196761 https://reactome.org/PathwayBrowser/#/R-SCE-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Saccharomyces cerevisiae 456215 R-SCE-196955 https://reactome.org/PathwayBrowser/#/R-SCE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Saccharomyces cerevisiae 456215 R-SCE-197271 https://reactome.org/PathwayBrowser/#/R-SCE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Saccharomyces cerevisiae 456215 R-SCE-201035 https://reactome.org/PathwayBrowser/#/R-SCE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Saccharomyces cerevisiae 456215 R-SCE-2393939 https://reactome.org/PathwayBrowser/#/R-SCE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Saccharomyces cerevisiae 456215 R-SCE-2990833 https://reactome.org/PathwayBrowser/#/R-SCE-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Saccharomyces cerevisiae 456215 R-SCE-2993802 https://reactome.org/PathwayBrowser/#/R-SCE-2993802 HLCS biotinylates PC:Mn2+ IEA Saccharomyces cerevisiae 456215 R-SCE-2993814 https://reactome.org/PathwayBrowser/#/R-SCE-2993814 HLCS biotinylates ACACA:Mn2+ IEA Saccharomyces cerevisiae 456215 R-SCE-380930 https://reactome.org/PathwayBrowser/#/R-SCE-380930 Phosphorylated AMPK binds AMP IEA Saccharomyces cerevisiae 456215 R-SCE-389622 https://reactome.org/PathwayBrowser/#/R-SCE-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 456215 R-SCE-389632 https://reactome.org/PathwayBrowser/#/R-SCE-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 456215 R-SCE-4167511 https://reactome.org/PathwayBrowser/#/R-SCE-4167511 HLCS biotinylates ACACB IEA Saccharomyces cerevisiae 456215 R-SCE-429913 https://reactome.org/PathwayBrowser/#/R-SCE-429913 5' to 3' Exoribonuclease Digestion of Decapped mRNA (yeast) TAS Saccharomyces cerevisiae 456215 R-SCE-430021 https://reactome.org/PathwayBrowser/#/R-SCE-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Saccharomyces cerevisiae 456215 R-SCE-430028 https://reactome.org/PathwayBrowser/#/R-SCE-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Saccharomyces cerevisiae 456215 R-SCE-434382 https://reactome.org/PathwayBrowser/#/R-SCE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Saccharomyces cerevisiae 456215 R-SCE-449911 https://reactome.org/PathwayBrowser/#/R-SCE-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Saccharomyces cerevisiae 456215 R-SCE-453338 https://reactome.org/PathwayBrowser/#/R-SCE-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP IEA Saccharomyces cerevisiae 456215 R-SCE-453342 https://reactome.org/PathwayBrowser/#/R-SCE-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Saccharomyces cerevisiae 456215 R-SCE-5358475 https://reactome.org/PathwayBrowser/#/R-SCE-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Saccharomyces cerevisiae 456215 R-SCE-5358592 https://reactome.org/PathwayBrowser/#/R-SCE-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Saccharomyces cerevisiae 456215 R-SCE-548843 https://reactome.org/PathwayBrowser/#/R-SCE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Saccharomyces cerevisiae 456215 R-SCE-5665868 https://reactome.org/PathwayBrowser/#/R-SCE-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Saccharomyces cerevisiae 456215 R-SCE-5672008 https://reactome.org/PathwayBrowser/#/R-SCE-5672008 Thr-180 of ULK1 is phosphorylated IEA Saccharomyces cerevisiae 456215 R-SCE-5672011 https://reactome.org/PathwayBrowser/#/R-SCE-5672011 p-AMPK:AMP binds the ULK complex IEA Saccharomyces cerevisiae 456215 R-SCE-5675868 https://reactome.org/PathwayBrowser/#/R-SCE-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Saccharomyces cerevisiae 456215 R-SCE-5679205 https://reactome.org/PathwayBrowser/#/R-SCE-5679205 ULK1 phosphorylates Beclin-1 IEA Saccharomyces cerevisiae 456215 R-SCE-5679239 https://reactome.org/PathwayBrowser/#/R-SCE-5679239 ULK complex translocates to the ER IEA Saccharomyces cerevisiae 456215 R-SCE-6784469 https://reactome.org/PathwayBrowser/#/R-SCE-6784469 EKC/KEOPS complex threonylcarbamoylates adenosine-37 of tRNAs TAS Saccharomyces cerevisiae 456215 R-SCE-6788798 https://reactome.org/PathwayBrowser/#/R-SCE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 456215 R-SCE-6788810 https://reactome.org/PathwayBrowser/#/R-SCE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 456215 R-SCE-6809287 https://reactome.org/PathwayBrowser/#/R-SCE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Saccharomyces cerevisiae 456215 R-SCE-70467 https://reactome.org/PathwayBrowser/#/R-SCE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 456215 R-SCE-70479 https://reactome.org/PathwayBrowser/#/R-SCE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Saccharomyces cerevisiae 456215 R-SCE-70599 https://reactome.org/PathwayBrowser/#/R-SCE-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Saccharomyces cerevisiae 456215 R-SCE-71735 https://reactome.org/PathwayBrowser/#/R-SCE-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Saccharomyces cerevisiae 456215 R-SCE-73580 https://reactome.org/PathwayBrowser/#/R-SCE-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Saccharomyces cerevisiae 456215 R-SCE-73792 https://reactome.org/PathwayBrowser/#/R-SCE-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Saccharomyces cerevisiae 456215 R-SCE-73828 https://reactome.org/PathwayBrowser/#/R-SCE-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Saccharomyces cerevisiae 456215 R-SCE-74213 https://reactome.org/PathwayBrowser/#/R-SCE-74213 APRT catalyzes the conversion of adenine to AMP IEA Saccharomyces cerevisiae 456215 R-SCE-76590 https://reactome.org/PathwayBrowser/#/R-SCE-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Saccharomyces cerevisiae 456215 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 456215 R-SCE-8852133 https://reactome.org/PathwayBrowser/#/R-SCE-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Saccharomyces cerevisiae 456215 R-SCE-8852136 https://reactome.org/PathwayBrowser/#/R-SCE-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Saccharomyces cerevisiae 456215 R-SCE-8951648 https://reactome.org/PathwayBrowser/#/R-SCE-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Saccharomyces cerevisiae 456215 R-SCE-8951656 https://reactome.org/PathwayBrowser/#/R-SCE-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Saccharomyces cerevisiae 456215 R-SCE-9613494 https://reactome.org/PathwayBrowser/#/R-SCE-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Saccharomyces cerevisiae 456215 R-SCE-9734535 https://reactome.org/PathwayBrowser/#/R-SCE-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Saccharomyces cerevisiae 456215 R-SCE-9748957 https://reactome.org/PathwayBrowser/#/R-SCE-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Saccharomyces cerevisiae 456215 R-SCE-983140 https://reactome.org/PathwayBrowser/#/R-SCE-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Saccharomyces cerevisiae 456215 R-SCE-983153 https://reactome.org/PathwayBrowser/#/R-SCE-983153 E1 mediated ubiquitin activation IEA Saccharomyces cerevisiae 456215 R-SCE-983156 https://reactome.org/PathwayBrowser/#/R-SCE-983156 Polyubiquitination of substrate IEA Saccharomyces cerevisiae 456215 R-SPO-109624 https://reactome.org/PathwayBrowser/#/R-SPO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Schizosaccharomyces pombe 456215 R-SPO-110144 https://reactome.org/PathwayBrowser/#/R-SPO-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Schizosaccharomyces pombe 456215 R-SPO-110145 https://reactome.org/PathwayBrowser/#/R-SPO-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Schizosaccharomyces pombe 456215 R-SPO-1632857 https://reactome.org/PathwayBrowser/#/R-SPO-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Schizosaccharomyces pombe 456215 R-SPO-163664 https://reactome.org/PathwayBrowser/#/R-SPO-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Schizosaccharomyces pombe 456215 R-SPO-169260 https://reactome.org/PathwayBrowser/#/R-SPO-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Schizosaccharomyces pombe 456215 R-SPO-169270 https://reactome.org/PathwayBrowser/#/R-SPO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Schizosaccharomyces pombe 456215 R-SPO-196753 https://reactome.org/PathwayBrowser/#/R-SPO-196753 2xPPCS ligates PPanK with Cys IEA Schizosaccharomyces pombe 456215 R-SPO-196761 https://reactome.org/PathwayBrowser/#/R-SPO-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Schizosaccharomyces pombe 456215 R-SPO-196955 https://reactome.org/PathwayBrowser/#/R-SPO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Schizosaccharomyces pombe 456215 R-SPO-197271 https://reactome.org/PathwayBrowser/#/R-SPO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Schizosaccharomyces pombe 456215 R-SPO-201035 https://reactome.org/PathwayBrowser/#/R-SPO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Schizosaccharomyces pombe 456215 R-SPO-2393939 https://reactome.org/PathwayBrowser/#/R-SPO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Schizosaccharomyces pombe 456215 R-SPO-2990833 https://reactome.org/PathwayBrowser/#/R-SPO-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Schizosaccharomyces pombe 456215 R-SPO-2993802 https://reactome.org/PathwayBrowser/#/R-SPO-2993802 HLCS biotinylates PC:Mn2+ IEA Schizosaccharomyces pombe 456215 R-SPO-2993814 https://reactome.org/PathwayBrowser/#/R-SPO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Schizosaccharomyces pombe 456215 R-SPO-380927 https://reactome.org/PathwayBrowser/#/R-SPO-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Schizosaccharomyces pombe 456215 R-SPO-380930 https://reactome.org/PathwayBrowser/#/R-SPO-380930 Phosphorylated AMPK binds AMP IEA Schizosaccharomyces pombe 456215 R-SPO-4167511 https://reactome.org/PathwayBrowser/#/R-SPO-4167511 HLCS biotinylates ACACB IEA Schizosaccharomyces pombe 456215 R-SPO-430028 https://reactome.org/PathwayBrowser/#/R-SPO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Schizosaccharomyces pombe 456215 R-SPO-434382 https://reactome.org/PathwayBrowser/#/R-SPO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Schizosaccharomyces pombe 456215 R-SPO-449911 https://reactome.org/PathwayBrowser/#/R-SPO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Schizosaccharomyces pombe 456215 R-SPO-5358475 https://reactome.org/PathwayBrowser/#/R-SPO-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Schizosaccharomyces pombe 456215 R-SPO-5358592 https://reactome.org/PathwayBrowser/#/R-SPO-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Schizosaccharomyces pombe 456215 R-SPO-548843 https://reactome.org/PathwayBrowser/#/R-SPO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Schizosaccharomyces pombe 456215 R-SPO-5665868 https://reactome.org/PathwayBrowser/#/R-SPO-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Schizosaccharomyces pombe 456215 R-SPO-5672008 https://reactome.org/PathwayBrowser/#/R-SPO-5672008 Thr-180 of ULK1 is phosphorylated IEA Schizosaccharomyces pombe 456215 R-SPO-5672011 https://reactome.org/PathwayBrowser/#/R-SPO-5672011 p-AMPK:AMP binds the ULK complex IEA Schizosaccharomyces pombe 456215 R-SPO-5675868 https://reactome.org/PathwayBrowser/#/R-SPO-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Schizosaccharomyces pombe 456215 R-SPO-5679205 https://reactome.org/PathwayBrowser/#/R-SPO-5679205 ULK1 phosphorylates Beclin-1 IEA Schizosaccharomyces pombe 456215 R-SPO-5679239 https://reactome.org/PathwayBrowser/#/R-SPO-5679239 ULK complex translocates to the ER IEA Schizosaccharomyces pombe 456215 R-SPO-6788810 https://reactome.org/PathwayBrowser/#/R-SPO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Schizosaccharomyces pombe 456215 R-SPO-6809287 https://reactome.org/PathwayBrowser/#/R-SPO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Schizosaccharomyces pombe 456215 R-SPO-69144 https://reactome.org/PathwayBrowser/#/R-SPO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Schizosaccharomyces pombe 456215 R-SPO-70467 https://reactome.org/PathwayBrowser/#/R-SPO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 456215 R-SPO-70479 https://reactome.org/PathwayBrowser/#/R-SPO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Schizosaccharomyces pombe 456215 R-SPO-70599 https://reactome.org/PathwayBrowser/#/R-SPO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Schizosaccharomyces pombe 456215 R-SPO-71735 https://reactome.org/PathwayBrowser/#/R-SPO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Schizosaccharomyces pombe 456215 R-SPO-73580 https://reactome.org/PathwayBrowser/#/R-SPO-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Schizosaccharomyces pombe 456215 R-SPO-73792 https://reactome.org/PathwayBrowser/#/R-SPO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Schizosaccharomyces pombe 456215 R-SPO-73828 https://reactome.org/PathwayBrowser/#/R-SPO-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Schizosaccharomyces pombe 456215 R-SPO-74213 https://reactome.org/PathwayBrowser/#/R-SPO-74213 APRT catalyzes the conversion of adenine to AMP IEA Schizosaccharomyces pombe 456215 R-SPO-76590 https://reactome.org/PathwayBrowser/#/R-SPO-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Schizosaccharomyces pombe 456215 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 456215 R-SPO-8852133 https://reactome.org/PathwayBrowser/#/R-SPO-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Schizosaccharomyces pombe 456215 R-SPO-8852136 https://reactome.org/PathwayBrowser/#/R-SPO-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Schizosaccharomyces pombe 456215 R-SPO-8951648 https://reactome.org/PathwayBrowser/#/R-SPO-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Schizosaccharomyces pombe 456215 R-SPO-8951656 https://reactome.org/PathwayBrowser/#/R-SPO-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Schizosaccharomyces pombe 456215 R-SPO-9613494 https://reactome.org/PathwayBrowser/#/R-SPO-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Schizosaccharomyces pombe 456215 R-SPO-9748957 https://reactome.org/PathwayBrowser/#/R-SPO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Schizosaccharomyces pombe 456215 R-SPO-983140 https://reactome.org/PathwayBrowser/#/R-SPO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Schizosaccharomyces pombe 456215 R-SPO-983153 https://reactome.org/PathwayBrowser/#/R-SPO-983153 E1 mediated ubiquitin activation IEA Schizosaccharomyces pombe 456215 R-SPO-983156 https://reactome.org/PathwayBrowser/#/R-SPO-983156 Polyubiquitination of substrate IEA Schizosaccharomyces pombe 456215 R-SSC-1008248 https://reactome.org/PathwayBrowser/#/R-SSC-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Sus scrofa 456215 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 456215 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 456215 R-SSC-109415 https://reactome.org/PathwayBrowser/#/R-SSC-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Sus scrofa 456215 R-SSC-109624 https://reactome.org/PathwayBrowser/#/R-SSC-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Sus scrofa 456215 R-SSC-110137 https://reactome.org/PathwayBrowser/#/R-SSC-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Sus scrofa 456215 R-SSC-110138 https://reactome.org/PathwayBrowser/#/R-SSC-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 456215 R-SSC-110141 https://reactome.org/PathwayBrowser/#/R-SSC-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Sus scrofa 456215 R-SSC-110144 https://reactome.org/PathwayBrowser/#/R-SSC-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Sus scrofa 456215 R-SSC-110145 https://reactome.org/PathwayBrowser/#/R-SSC-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Sus scrofa 456215 R-SSC-111285 https://reactome.org/PathwayBrowser/#/R-SSC-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Sus scrofa 456215 R-SSC-111955 https://reactome.org/PathwayBrowser/#/R-SSC-111955 cAMP hydrolysis by Cam-PDE 1 IEA Sus scrofa 456215 R-SSC-111962 https://reactome.org/PathwayBrowser/#/R-SSC-111962 PDE4A,C,D hydrolyse cAMP IEA Sus scrofa 456215 R-SSC-1169394 https://reactome.org/PathwayBrowser/#/R-SSC-1169394 ISGylation of IRF3 IEA Sus scrofa 456215 R-SSC-1169397 https://reactome.org/PathwayBrowser/#/R-SSC-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Sus scrofa 456215 R-SSC-1169398 https://reactome.org/PathwayBrowser/#/R-SSC-1169398 ISGylation of host protein filamin B IEA Sus scrofa 456215 R-SSC-1169402 https://reactome.org/PathwayBrowser/#/R-SSC-1169402 ISGylation of E2 conjugating enzymes IEA Sus scrofa 456215 R-SSC-1169405 https://reactome.org/PathwayBrowser/#/R-SSC-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Sus scrofa 456215 R-SSC-1169406 https://reactome.org/PathwayBrowser/#/R-SSC-1169406 ISGylation of host proteins IEA Sus scrofa 456215 R-SSC-159425 https://reactome.org/PathwayBrowser/#/R-SSC-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 456215 R-SSC-159443 https://reactome.org/PathwayBrowser/#/R-SSC-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 456215 R-SSC-159567 https://reactome.org/PathwayBrowser/#/R-SSC-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Sus scrofa 456215 R-SSC-162425 https://reactome.org/PathwayBrowser/#/R-SSC-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Sus scrofa 456215 R-SSC-1632857 https://reactome.org/PathwayBrowser/#/R-SSC-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Sus scrofa 456215 R-SSC-163664 https://reactome.org/PathwayBrowser/#/R-SSC-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Sus scrofa 456215 R-SSC-169260 https://reactome.org/PathwayBrowser/#/R-SSC-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Sus scrofa 456215 R-SSC-169270 https://reactome.org/PathwayBrowser/#/R-SSC-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Sus scrofa 456215 R-SSC-174441 https://reactome.org/PathwayBrowser/#/R-SSC-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Sus scrofa 456215 R-SSC-176606 https://reactome.org/PathwayBrowser/#/R-SSC-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Sus scrofa 456215 R-SSC-177157 https://reactome.org/PathwayBrowser/#/R-SSC-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Sus scrofa 456215 R-SSC-192137 https://reactome.org/PathwayBrowser/#/R-SSC-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 456215 R-SSC-193401 https://reactome.org/PathwayBrowser/#/R-SSC-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 456215 R-SSC-193407 https://reactome.org/PathwayBrowser/#/R-SSC-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 456215 R-SSC-193424 https://reactome.org/PathwayBrowser/#/R-SSC-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 456215 R-SSC-193711 https://reactome.org/PathwayBrowser/#/R-SSC-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 456215 R-SSC-193727 https://reactome.org/PathwayBrowser/#/R-SSC-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 456215 R-SSC-193743 https://reactome.org/PathwayBrowser/#/R-SSC-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 456215 R-SSC-193766 https://reactome.org/PathwayBrowser/#/R-SSC-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 456215 R-SSC-196753 https://reactome.org/PathwayBrowser/#/R-SSC-196753 2xPPCS ligates PPanK with Cys IEA Sus scrofa 456215 R-SSC-196761 https://reactome.org/PathwayBrowser/#/R-SSC-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Sus scrofa 456215 R-SSC-196955 https://reactome.org/PathwayBrowser/#/R-SSC-196955 2xENPP1 hydrolyzes FAD to FMN IEA Sus scrofa 456215 R-SSC-197271 https://reactome.org/PathwayBrowser/#/R-SSC-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Sus scrofa 456215 R-SSC-200421 https://reactome.org/PathwayBrowser/#/R-SSC-200421 Activation of cytosolic AMPK by phosphorylation IEA Sus scrofa 456215 R-SSC-201035 https://reactome.org/PathwayBrowser/#/R-SSC-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Sus scrofa 456215 R-SSC-2046085 https://reactome.org/PathwayBrowser/#/R-SSC-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Sus scrofa 456215 R-SSC-2046098 https://reactome.org/PathwayBrowser/#/R-SSC-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Sus scrofa 456215 R-SSC-2393939 https://reactome.org/PathwayBrowser/#/R-SSC-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 456215 R-SSC-2393954 https://reactome.org/PathwayBrowser/#/R-SSC-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 456215 R-SSC-2730904 https://reactome.org/PathwayBrowser/#/R-SSC-2730904 Auto-ubiquitination of TRAF6 IEA Sus scrofa 456215 R-SSC-2990833 https://reactome.org/PathwayBrowser/#/R-SSC-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Sus scrofa 456215 R-SSC-2993447 https://reactome.org/PathwayBrowser/#/R-SSC-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Sus scrofa 456215 R-SSC-2993799 https://reactome.org/PathwayBrowser/#/R-SSC-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Sus scrofa 456215 R-SSC-2993802 https://reactome.org/PathwayBrowser/#/R-SSC-2993802 HLCS biotinylates PC:Mn2+ IEA Sus scrofa 456215 R-SSC-2993814 https://reactome.org/PathwayBrowser/#/R-SSC-2993814 HLCS biotinylates ACACA:Mn2+ IEA Sus scrofa 456215 R-SSC-380927 https://reactome.org/PathwayBrowser/#/R-SSC-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Sus scrofa 456215 R-SSC-380930 https://reactome.org/PathwayBrowser/#/R-SSC-380930 Phosphorylated AMPK binds AMP IEA Sus scrofa 456215 R-SSC-389622 https://reactome.org/PathwayBrowser/#/R-SSC-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 456215 R-SSC-389632 https://reactome.org/PathwayBrowser/#/R-SSC-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 456215 R-SSC-389652 https://reactome.org/PathwayBrowser/#/R-SSC-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP IEA Sus scrofa 456215 R-SSC-4167511 https://reactome.org/PathwayBrowser/#/R-SSC-4167511 HLCS biotinylates ACACB IEA Sus scrofa 456215 R-SSC-418553 https://reactome.org/PathwayBrowser/#/R-SSC-418553 cAMP degradation by Phosphodiesterases IEA Sus scrofa 456215 R-SSC-429955 https://reactome.org/PathwayBrowser/#/R-SSC-429955 CCR4-NOT complex deadenylates mRNA IEA Sus scrofa 456215 R-SSC-429992 https://reactome.org/PathwayBrowser/#/R-SSC-429992 PARN deadenylates mRNA IEA Sus scrofa 456215 R-SSC-430021 https://reactome.org/PathwayBrowser/#/R-SSC-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Sus scrofa 456215 R-SSC-430028 https://reactome.org/PathwayBrowser/#/R-SSC-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Sus scrofa 456215 R-SSC-434382 https://reactome.org/PathwayBrowser/#/R-SSC-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Sus scrofa 456215 R-SSC-447074 https://reactome.org/PathwayBrowser/#/R-SSC-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Sus scrofa 456215 R-SSC-449911 https://reactome.org/PathwayBrowser/#/R-SSC-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Sus scrofa 456215 R-SSC-453338 https://reactome.org/PathwayBrowser/#/R-SSC-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP IEA Sus scrofa 456215 R-SSC-453342 https://reactome.org/PathwayBrowser/#/R-SSC-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Sus scrofa 456215 R-SSC-5358475 https://reactome.org/PathwayBrowser/#/R-SSC-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Sus scrofa 456215 R-SSC-5358592 https://reactome.org/PathwayBrowser/#/R-SSC-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Sus scrofa 456215 R-SSC-548843 https://reactome.org/PathwayBrowser/#/R-SSC-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Sus scrofa 456215 R-SSC-5607756 https://reactome.org/PathwayBrowser/#/R-SSC-5607756 TRAF6 oligomer autoubiquitinates IEA Sus scrofa 456215 R-SSC-5607757 https://reactome.org/PathwayBrowser/#/R-SSC-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 IEA Sus scrofa 456215 R-SSC-5631941 https://reactome.org/PathwayBrowser/#/R-SSC-5631941 SESN1,2,3 bind AMPK IEA Sus scrofa 456215 R-SSC-5665868 https://reactome.org/PathwayBrowser/#/R-SSC-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Sus scrofa 456215 R-SSC-5672008 https://reactome.org/PathwayBrowser/#/R-SSC-5672008 Thr-180 of ULK1 is phosphorylated IEA Sus scrofa 456215 R-SSC-5672011 https://reactome.org/PathwayBrowser/#/R-SSC-5672011 p-AMPK:AMP binds the ULK complex IEA Sus scrofa 456215 R-SSC-5673768 https://reactome.org/PathwayBrowser/#/R-SSC-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Sus scrofa 456215 R-SSC-5675868 https://reactome.org/PathwayBrowser/#/R-SSC-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Sus scrofa 456215 R-SSC-5679205 https://reactome.org/PathwayBrowser/#/R-SSC-5679205 ULK1 phosphorylates Beclin-1 IEA Sus scrofa 456215 R-SSC-5679239 https://reactome.org/PathwayBrowser/#/R-SSC-5679239 ULK complex translocates to the ER IEA Sus scrofa 456215 R-SSC-5694494 https://reactome.org/PathwayBrowser/#/R-SSC-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Sus scrofa 456215 R-SSC-5695957 https://reactome.org/PathwayBrowser/#/R-SSC-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Sus scrofa 456215 R-SSC-5696004 https://reactome.org/PathwayBrowser/#/R-SSC-5696004 ACSF2 ligates CoA-SH to MCFA IEA Sus scrofa 456215 R-SSC-5696007 https://reactome.org/PathwayBrowser/#/R-SSC-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Sus scrofa 456215 R-SSC-5696021 https://reactome.org/PathwayBrowser/#/R-SSC-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Sus scrofa 456215 R-SSC-5696049 https://reactome.org/PathwayBrowser/#/R-SSC-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 456215 R-SSC-6788798 https://reactome.org/PathwayBrowser/#/R-SSC-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 456215 R-SSC-6788810 https://reactome.org/PathwayBrowser/#/R-SSC-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 456215 R-SSC-6805470 https://reactome.org/PathwayBrowser/#/R-SSC-6805470 AMPK phosphorylates TP53 IEA Sus scrofa 456215 R-SSC-6809287 https://reactome.org/PathwayBrowser/#/R-SSC-6809287 NUDT12 hydrolyses NADH to NMNH IEA Sus scrofa 456215 R-SSC-69144 https://reactome.org/PathwayBrowser/#/R-SSC-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Sus scrofa 456215 R-SSC-70467 https://reactome.org/PathwayBrowser/#/R-SSC-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Sus scrofa 456215 R-SSC-70479 https://reactome.org/PathwayBrowser/#/R-SSC-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Sus scrofa 456215 R-SSC-70577 https://reactome.org/PathwayBrowser/#/R-SSC-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Sus scrofa 456215 R-SSC-70599 https://reactome.org/PathwayBrowser/#/R-SSC-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Sus scrofa 456215 R-SSC-71735 https://reactome.org/PathwayBrowser/#/R-SSC-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Sus scrofa 456215 R-SSC-73580 https://reactome.org/PathwayBrowser/#/R-SSC-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Sus scrofa 456215 R-SSC-73792 https://reactome.org/PathwayBrowser/#/R-SSC-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Sus scrofa 456215 R-SSC-73828 https://reactome.org/PathwayBrowser/#/R-SSC-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Sus scrofa 456215 R-SSC-74213 https://reactome.org/PathwayBrowser/#/R-SSC-74213 APRT catalyzes the conversion of adenine to AMP IEA Sus scrofa 456215 R-SSC-74220 https://reactome.org/PathwayBrowser/#/R-SSC-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Sus scrofa 456215 R-SSC-76590 https://reactome.org/PathwayBrowser/#/R-SSC-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Sus scrofa 456215 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 456215 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 456215 R-SSC-8852133 https://reactome.org/PathwayBrowser/#/R-SSC-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Sus scrofa 456215 R-SSC-8852136 https://reactome.org/PathwayBrowser/#/R-SSC-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Sus scrofa 456215 R-SSC-8875071 https://reactome.org/PathwayBrowser/#/R-SSC-8875071 ACSS3 ligates CoA to CH3COO- IEA Sus scrofa 456215 R-SSC-8953499 https://reactome.org/PathwayBrowser/#/R-SSC-8953499 IMPAD1 hydrolyses PAP to AMP IEA Sus scrofa 456215 R-SSC-8959510 https://reactome.org/PathwayBrowser/#/R-SSC-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Sus scrofa 456215 R-SSC-9009950 https://reactome.org/PathwayBrowser/#/R-SSC-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Sus scrofa 456215 R-SSC-947531 https://reactome.org/PathwayBrowser/#/R-SSC-947531 Molybdenum ion transfer onto molybdopterin IEA Sus scrofa 456215 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa 456215 R-SSC-9629675 https://reactome.org/PathwayBrowser/#/R-SSC-9629675 PDE3A hydrolyses cAMP to AMP IEA Sus scrofa 456215 R-SSC-9644869 https://reactome.org/PathwayBrowser/#/R-SSC-9644869 p-S54-PDE4B hydrolyses cAMP IEA Sus scrofa 456215 R-SSC-9705507 https://reactome.org/PathwayBrowser/#/R-SSC-9705507 PDE3B hydrolyses cAMP to AMP IEA Sus scrofa 456215 R-SSC-9708261 https://reactome.org/PathwayBrowser/#/R-SSC-9708261 PDE4A hydrolyses cAMP to AMP IEA Sus scrofa 456215 R-SSC-9734535 https://reactome.org/PathwayBrowser/#/R-SSC-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Sus scrofa 456215 R-SSC-9748957 https://reactome.org/PathwayBrowser/#/R-SSC-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Sus scrofa 456215 R-SSC-9749971 https://reactome.org/PathwayBrowser/#/R-SSC-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Sus scrofa 456215 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa 456215 R-SSC-983153 https://reactome.org/PathwayBrowser/#/R-SSC-983153 E1 mediated ubiquitin activation IEA Sus scrofa 456215 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa 456215 R-SSC-9833973 https://reactome.org/PathwayBrowser/#/R-SSC-9833973 ISGylation of PKR IEA Sus scrofa 456215 R-TAE-2408513 https://reactome.org/PathwayBrowser/#/R-TAE-2408513 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Triticum aestivum 456215 R-VRA-2408510 https://reactome.org/PathwayBrowser/#/R-VRA-2408510 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Vigna radiata var. radiata 456215 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 456215 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 456215 R-XTR-109415 https://reactome.org/PathwayBrowser/#/R-XTR-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Xenopus tropicalis 456215 R-XTR-109624 https://reactome.org/PathwayBrowser/#/R-XTR-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Xenopus tropicalis 456215 R-XTR-110137 https://reactome.org/PathwayBrowser/#/R-XTR-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Xenopus tropicalis 456215 R-XTR-110138 https://reactome.org/PathwayBrowser/#/R-XTR-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 456215 R-XTR-110144 https://reactome.org/PathwayBrowser/#/R-XTR-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Xenopus tropicalis 456215 R-XTR-110145 https://reactome.org/PathwayBrowser/#/R-XTR-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Xenopus tropicalis 456215 R-XTR-111285 https://reactome.org/PathwayBrowser/#/R-XTR-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Xenopus tropicalis 456215 R-XTR-111955 https://reactome.org/PathwayBrowser/#/R-XTR-111955 cAMP hydrolysis by Cam-PDE 1 IEA Xenopus tropicalis 456215 R-XTR-111962 https://reactome.org/PathwayBrowser/#/R-XTR-111962 PDE4A,C,D hydrolyse cAMP IEA Xenopus tropicalis 456215 R-XTR-159425 https://reactome.org/PathwayBrowser/#/R-XTR-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 456215 R-XTR-159443 https://reactome.org/PathwayBrowser/#/R-XTR-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 456215 R-XTR-159567 https://reactome.org/PathwayBrowser/#/R-XTR-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Xenopus tropicalis 456215 R-XTR-162425 https://reactome.org/PathwayBrowser/#/R-XTR-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Xenopus tropicalis 456215 R-XTR-1632857 https://reactome.org/PathwayBrowser/#/R-XTR-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Xenopus tropicalis 456215 R-XTR-169260 https://reactome.org/PathwayBrowser/#/R-XTR-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Xenopus tropicalis 456215 R-XTR-169270 https://reactome.org/PathwayBrowser/#/R-XTR-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Xenopus tropicalis 456215 R-XTR-176606 https://reactome.org/PathwayBrowser/#/R-XTR-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Xenopus tropicalis 456215 R-XTR-177157 https://reactome.org/PathwayBrowser/#/R-XTR-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 456215 R-XTR-192137 https://reactome.org/PathwayBrowser/#/R-XTR-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 456215 R-XTR-193401 https://reactome.org/PathwayBrowser/#/R-XTR-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 456215 R-XTR-193407 https://reactome.org/PathwayBrowser/#/R-XTR-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 456215 R-XTR-193424 https://reactome.org/PathwayBrowser/#/R-XTR-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 456215 R-XTR-193711 https://reactome.org/PathwayBrowser/#/R-XTR-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 456215 R-XTR-193727 https://reactome.org/PathwayBrowser/#/R-XTR-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 456215 R-XTR-193743 https://reactome.org/PathwayBrowser/#/R-XTR-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 456215 R-XTR-193766 https://reactome.org/PathwayBrowser/#/R-XTR-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 456215 R-XTR-196753 https://reactome.org/PathwayBrowser/#/R-XTR-196753 2xPPCS ligates PPanK with Cys IEA Xenopus tropicalis 456215 R-XTR-196761 https://reactome.org/PathwayBrowser/#/R-XTR-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Xenopus tropicalis 456215 R-XTR-196955 https://reactome.org/PathwayBrowser/#/R-XTR-196955 2xENPP1 hydrolyzes FAD to FMN IEA Xenopus tropicalis 456215 R-XTR-201035 https://reactome.org/PathwayBrowser/#/R-XTR-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Xenopus tropicalis 456215 R-XTR-2046085 https://reactome.org/PathwayBrowser/#/R-XTR-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Xenopus tropicalis 456215 R-XTR-2046098 https://reactome.org/PathwayBrowser/#/R-XTR-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Xenopus tropicalis 456215 R-XTR-2393939 https://reactome.org/PathwayBrowser/#/R-XTR-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 456215 R-XTR-2393954 https://reactome.org/PathwayBrowser/#/R-XTR-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 456215 R-XTR-2990833 https://reactome.org/PathwayBrowser/#/R-XTR-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Xenopus tropicalis 456215 R-XTR-2993447 https://reactome.org/PathwayBrowser/#/R-XTR-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Xenopus tropicalis 456215 R-XTR-2993799 https://reactome.org/PathwayBrowser/#/R-XTR-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Xenopus tropicalis 456215 R-XTR-2993802 https://reactome.org/PathwayBrowser/#/R-XTR-2993802 HLCS biotinylates PC:Mn2+ IEA Xenopus tropicalis 456215 R-XTR-2993814 https://reactome.org/PathwayBrowser/#/R-XTR-2993814 HLCS biotinylates ACACA:Mn2+ IEA Xenopus tropicalis 456215 R-XTR-389622 https://reactome.org/PathwayBrowser/#/R-XTR-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 456215 R-XTR-389632 https://reactome.org/PathwayBrowser/#/R-XTR-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 456215 R-XTR-4167511 https://reactome.org/PathwayBrowser/#/R-XTR-4167511 HLCS biotinylates ACACB IEA Xenopus tropicalis 456215 R-XTR-418553 https://reactome.org/PathwayBrowser/#/R-XTR-418553 cAMP degradation by Phosphodiesterases IEA Xenopus tropicalis 456215 R-XTR-429955 https://reactome.org/PathwayBrowser/#/R-XTR-429955 CCR4-NOT complex deadenylates mRNA IEA Xenopus tropicalis 456215 R-XTR-429992 https://reactome.org/PathwayBrowser/#/R-XTR-429992 PARN deadenylates mRNA IEA Xenopus tropicalis 456215 R-XTR-430028 https://reactome.org/PathwayBrowser/#/R-XTR-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Xenopus tropicalis 456215 R-XTR-434382 https://reactome.org/PathwayBrowser/#/R-XTR-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Xenopus tropicalis 456215 R-XTR-449911 https://reactome.org/PathwayBrowser/#/R-XTR-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Xenopus tropicalis 456215 R-XTR-453338 https://reactome.org/PathwayBrowser/#/R-XTR-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP IEA Xenopus tropicalis 456215 R-XTR-453342 https://reactome.org/PathwayBrowser/#/R-XTR-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Xenopus tropicalis 456215 R-XTR-5358475 https://reactome.org/PathwayBrowser/#/R-XTR-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Xenopus tropicalis 456215 R-XTR-548843 https://reactome.org/PathwayBrowser/#/R-XTR-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Xenopus tropicalis 456215 R-XTR-5665868 https://reactome.org/PathwayBrowser/#/R-XTR-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Xenopus tropicalis 456215 R-XTR-5672008 https://reactome.org/PathwayBrowser/#/R-XTR-5672008 Thr-180 of ULK1 is phosphorylated IEA Xenopus tropicalis 456215 R-XTR-5675868 https://reactome.org/PathwayBrowser/#/R-XTR-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Xenopus tropicalis 456215 R-XTR-5679205 https://reactome.org/PathwayBrowser/#/R-XTR-5679205 ULK1 phosphorylates Beclin-1 IEA Xenopus tropicalis 456215 R-XTR-5679239 https://reactome.org/PathwayBrowser/#/R-XTR-5679239 ULK complex translocates to the ER IEA Xenopus tropicalis 456215 R-XTR-5694494 https://reactome.org/PathwayBrowser/#/R-XTR-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Xenopus tropicalis 456215 R-XTR-5696004 https://reactome.org/PathwayBrowser/#/R-XTR-5696004 ACSF2 ligates CoA-SH to MCFA IEA Xenopus tropicalis 456215 R-XTR-5696021 https://reactome.org/PathwayBrowser/#/R-XTR-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Xenopus tropicalis 456215 R-XTR-5696049 https://reactome.org/PathwayBrowser/#/R-XTR-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 456215 R-XTR-6788798 https://reactome.org/PathwayBrowser/#/R-XTR-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 456215 R-XTR-6788810 https://reactome.org/PathwayBrowser/#/R-XTR-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 456215 R-XTR-6809287 https://reactome.org/PathwayBrowser/#/R-XTR-6809287 NUDT12 hydrolyses NADH to NMNH IEA Xenopus tropicalis 456215 R-XTR-70479 https://reactome.org/PathwayBrowser/#/R-XTR-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Xenopus tropicalis 456215 R-XTR-70599 https://reactome.org/PathwayBrowser/#/R-XTR-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Xenopus tropicalis 456215 R-XTR-71735 https://reactome.org/PathwayBrowser/#/R-XTR-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Xenopus tropicalis 456215 R-XTR-73580 https://reactome.org/PathwayBrowser/#/R-XTR-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Xenopus tropicalis 456215 R-XTR-73792 https://reactome.org/PathwayBrowser/#/R-XTR-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Xenopus tropicalis 456215 R-XTR-73828 https://reactome.org/PathwayBrowser/#/R-XTR-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Xenopus tropicalis 456215 R-XTR-74213 https://reactome.org/PathwayBrowser/#/R-XTR-74213 APRT catalyzes the conversion of adenine to AMP IEA Xenopus tropicalis 456215 R-XTR-76590 https://reactome.org/PathwayBrowser/#/R-XTR-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Xenopus tropicalis 456215 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 456215 R-XTR-8852133 https://reactome.org/PathwayBrowser/#/R-XTR-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Xenopus tropicalis 456215 R-XTR-8852136 https://reactome.org/PathwayBrowser/#/R-XTR-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Xenopus tropicalis 456215 R-XTR-8875071 https://reactome.org/PathwayBrowser/#/R-XTR-8875071 ACSS3 ligates CoA to CH3COO- IEA Xenopus tropicalis 456215 R-XTR-8953499 https://reactome.org/PathwayBrowser/#/R-XTR-8953499 IMPAD1 hydrolyses PAP to AMP IEA Xenopus tropicalis 456215 R-XTR-9613494 https://reactome.org/PathwayBrowser/#/R-XTR-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Xenopus tropicalis 456215 R-XTR-9644869 https://reactome.org/PathwayBrowser/#/R-XTR-9644869 p-S54-PDE4B hydrolyses cAMP IEA Xenopus tropicalis 456215 R-XTR-9705507 https://reactome.org/PathwayBrowser/#/R-XTR-9705507 PDE3B hydrolyses cAMP to AMP IEA Xenopus tropicalis 456215 R-XTR-9708261 https://reactome.org/PathwayBrowser/#/R-XTR-9708261 PDE4A hydrolyses cAMP to AMP IEA Xenopus tropicalis 456215 R-XTR-9734535 https://reactome.org/PathwayBrowser/#/R-XTR-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Xenopus tropicalis 456215 R-XTR-9748957 https://reactome.org/PathwayBrowser/#/R-XTR-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Xenopus tropicalis 456215 R-XTR-9749971 https://reactome.org/PathwayBrowser/#/R-XTR-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Xenopus tropicalis 456215 R-XTR-983140 https://reactome.org/PathwayBrowser/#/R-XTR-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Xenopus tropicalis 456215 R-XTR-983153 https://reactome.org/PathwayBrowser/#/R-XTR-983153 E1 mediated ubiquitin activation IEA Xenopus tropicalis 456215 R-XTR-983156 https://reactome.org/PathwayBrowser/#/R-XTR-983156 Polyubiquitination of substrate IEA Xenopus tropicalis 456216 R-BTA-1008248 https://reactome.org/PathwayBrowser/#/R-BTA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Bos taurus 456216 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 456216 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 456216 R-BTA-109415 https://reactome.org/PathwayBrowser/#/R-BTA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Bos taurus 456216 R-BTA-109624 https://reactome.org/PathwayBrowser/#/R-BTA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Bos taurus 456216 R-BTA-109671 https://reactome.org/PathwayBrowser/#/R-BTA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Bos taurus 456216 R-BTA-109699 https://reactome.org/PathwayBrowser/#/R-BTA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-109702 https://reactome.org/PathwayBrowser/#/R-BTA-109702 PDPK1 phosphorylates AKT2 IEA Bos taurus 456216 R-BTA-109759 https://reactome.org/PathwayBrowser/#/R-BTA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Bos taurus 456216 R-BTA-109822 https://reactome.org/PathwayBrowser/#/R-BTA-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Bos taurus 456216 R-BTA-109823 https://reactome.org/PathwayBrowser/#/R-BTA-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Bos taurus 456216 R-BTA-109860 https://reactome.org/PathwayBrowser/#/R-BTA-109860 MAP2K1 phosphorylates MAPK3 IEA Bos taurus 456216 R-BTA-109862 https://reactome.org/PathwayBrowser/#/R-BTA-109862 MAP2K2 phosphorylates MAPK1 IEA Bos taurus 456216 R-BTA-109903 https://reactome.org/PathwayBrowser/#/R-BTA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Bos taurus 456216 R-BTA-110133 https://reactome.org/PathwayBrowser/#/R-BTA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Bos taurus 456216 R-BTA-110137 https://reactome.org/PathwayBrowser/#/R-BTA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Bos taurus 456216 R-BTA-110138 https://reactome.org/PathwayBrowser/#/R-BTA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 456216 R-BTA-110141 https://reactome.org/PathwayBrowser/#/R-BTA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Bos taurus 456216 R-BTA-110144 https://reactome.org/PathwayBrowser/#/R-BTA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Bos taurus 456216 R-BTA-110145 https://reactome.org/PathwayBrowser/#/R-BTA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Bos taurus 456216 R-BTA-1112510 https://reactome.org/PathwayBrowser/#/R-BTA-1112510 IL6ST is tyrosine phosphorylated IEA Bos taurus 456216 R-BTA-1112514 https://reactome.org/PathwayBrowser/#/R-BTA-1112514 JAK activation IEA Bos taurus 456216 R-BTA-1112602 https://reactome.org/PathwayBrowser/#/R-BTA-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Bos taurus 456216 R-BTA-1112703 https://reactome.org/PathwayBrowser/#/R-BTA-1112703 PTPN11 is phosphorylated IEA Bos taurus 456216 R-BTA-1112727 https://reactome.org/PathwayBrowser/#/R-BTA-1112727 Serine phosphorylation of STATs IEA Bos taurus 456216 R-BTA-111898 https://reactome.org/PathwayBrowser/#/R-BTA-111898 Phosphorylation of cPLA2 by ERK-2 IEA Bos taurus 456216 R-BTA-111915 https://reactome.org/PathwayBrowser/#/R-BTA-111915 CAMK4 autophosphorylates IEA Bos taurus 456216 R-BTA-111970 https://reactome.org/PathwayBrowser/#/R-BTA-111970 PKC phosphorylates GRK2 IEA Bos taurus 456216 R-BTA-112342 https://reactome.org/PathwayBrowser/#/R-BTA-112342 Inactivation of MAP2K1 by CDK1 IEA Bos taurus 456216 R-BTA-112381 https://reactome.org/PathwayBrowser/#/R-BTA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Bos taurus 456216 R-BTA-114252 https://reactome.org/PathwayBrowser/#/R-BTA-114252 Cleavage of Procaspase-3 by the apoptosome IEA Bos taurus 456216 R-BTA-114254 https://reactome.org/PathwayBrowser/#/R-BTA-114254 CYCS binds to APAF1 IEA Bos taurus 456216 R-BTA-114259 https://reactome.org/PathwayBrowser/#/R-BTA-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Bos taurus 456216 R-BTA-114261 https://reactome.org/PathwayBrowser/#/R-BTA-114261 Cleavage of Procaspase-7 by the apoptosome IEA Bos taurus 456216 R-BTA-114600 https://reactome.org/PathwayBrowser/#/R-BTA-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Bos taurus 456216 R-BTA-114683 https://reactome.org/PathwayBrowser/#/R-BTA-114683 Phosphorylation of Platelet Sec-1 IEA Bos taurus 456216 R-BTA-114684 https://reactome.org/PathwayBrowser/#/R-BTA-114684 Phosphorylation of Syntaxin-4 IEA Bos taurus 456216 R-BTA-1168459 https://reactome.org/PathwayBrowser/#/R-BTA-1168459 Lyn activates ERK IEA Bos taurus 456216 R-BTA-1168635 https://reactome.org/PathwayBrowser/#/R-BTA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Bos taurus 456216 R-BTA-1168638 https://reactome.org/PathwayBrowser/#/R-BTA-1168638 Activated IKK phosphorylates I-kappaB IEA Bos taurus 456216 R-BTA-1181149 https://reactome.org/PathwayBrowser/#/R-BTA-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Bos taurus 456216 R-BTA-1226094 https://reactome.org/PathwayBrowser/#/R-BTA-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Bos taurus 456216 R-BTA-1226095 https://reactome.org/PathwayBrowser/#/R-BTA-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Bos taurus 456216 R-BTA-1247935 https://reactome.org/PathwayBrowser/#/R-BTA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Bos taurus 456216 R-BTA-1247960 https://reactome.org/PathwayBrowser/#/R-BTA-1247960 Activation of p38 MAPK IEA Bos taurus 456216 R-BTA-1250195 https://reactome.org/PathwayBrowser/#/R-BTA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Bos taurus 456216 R-BTA-1250315 https://reactome.org/PathwayBrowser/#/R-BTA-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Bos taurus 456216 R-BTA-1250348 https://reactome.org/PathwayBrowser/#/R-BTA-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Bos taurus 456216 R-BTA-1250370 https://reactome.org/PathwayBrowser/#/R-BTA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Bos taurus 456216 R-BTA-1250462 https://reactome.org/PathwayBrowser/#/R-BTA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Bos taurus 456216 R-BTA-1295540 https://reactome.org/PathwayBrowser/#/R-BTA-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Bos taurus 456216 R-BTA-1295609 https://reactome.org/PathwayBrowser/#/R-BTA-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Bos taurus 456216 R-BTA-1306957 https://reactome.org/PathwayBrowser/#/R-BTA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Bos taurus 456216 R-BTA-1306979 https://reactome.org/PathwayBrowser/#/R-BTA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Bos taurus 456216 R-BTA-1307963 https://reactome.org/PathwayBrowser/#/R-BTA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Bos taurus 456216 R-BTA-1362270 https://reactome.org/PathwayBrowser/#/R-BTA-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Bos taurus 456216 R-BTA-1369065 https://reactome.org/PathwayBrowser/#/R-BTA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Bos taurus 456216 R-BTA-139908 https://reactome.org/PathwayBrowser/#/R-BTA-139908 Phosphorylation of DLC2 by MAPK8 IEA Bos taurus 456216 R-BTA-139918 https://reactome.org/PathwayBrowser/#/R-BTA-139918 Phosphorylation of BIM by JNK IEA Bos taurus 456216 R-BTA-1433418 https://reactome.org/PathwayBrowser/#/R-BTA-1433418 Phosphorylation of JAK2 IEA Bos taurus 456216 R-BTA-1433454 https://reactome.org/PathwayBrowser/#/R-BTA-1433454 Phosphorylation of GAB2 by SFKs IEA Bos taurus 456216 R-BTA-1433488 https://reactome.org/PathwayBrowser/#/R-BTA-1433488 Phosphorylation of SHP2 by SFKs IEA Bos taurus 456216 R-BTA-1433506 https://reactome.org/PathwayBrowser/#/R-BTA-1433506 Phosphorylation of APS IEA Bos taurus 456216 R-BTA-1433514 https://reactome.org/PathwayBrowser/#/R-BTA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Bos taurus 456216 R-BTA-1433542 https://reactome.org/PathwayBrowser/#/R-BTA-1433542 Phosphorylation and activation of VAV1 IEA Bos taurus 456216 R-BTA-1454916 https://reactome.org/PathwayBrowser/#/R-BTA-1454916 The ABCC family mediates organic anion transport IEA Bos taurus 456216 R-BTA-1454928 https://reactome.org/PathwayBrowser/#/R-BTA-1454928 ABCG4 may mediate cholesterol efflux IEA Bos taurus 456216 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-1467466 https://reactome.org/PathwayBrowser/#/R-BTA-1467466 ABCA4 mediates atRAL transport IEA Bos taurus 456216 R-BTA-1470009 https://reactome.org/PathwayBrowser/#/R-BTA-1470009 Phosphorylation of STATs IEA Bos taurus 456216 R-BTA-1472121 https://reactome.org/PathwayBrowser/#/R-BTA-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Bos taurus 456216 R-BTA-1475422 https://reactome.org/PathwayBrowser/#/R-BTA-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Bos taurus 456216 R-BTA-1483004 https://reactome.org/PathwayBrowser/#/R-BTA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Bos taurus 456216 R-BTA-1483222 https://reactome.org/PathwayBrowser/#/R-BTA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Bos taurus 456216 R-BTA-1497853 https://reactome.org/PathwayBrowser/#/R-BTA-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Bos taurus 456216 R-BTA-1524186 https://reactome.org/PathwayBrowser/#/R-BTA-1524186 Phosphorylation of PLCgamma by PDGFR IEA Bos taurus 456216 R-BTA-1549526 https://reactome.org/PathwayBrowser/#/R-BTA-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Bos taurus 456216 R-BTA-156673 https://reactome.org/PathwayBrowser/#/R-BTA-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Bos taurus 456216 R-BTA-156678 https://reactome.org/PathwayBrowser/#/R-BTA-156678 Activation of Cdc25C IEA Bos taurus 456216 R-BTA-156682 https://reactome.org/PathwayBrowser/#/R-BTA-156682 PLK1 phosphorylates NUDC IEA Bos taurus 456216 R-BTA-156699 https://reactome.org/PathwayBrowser/#/R-BTA-156699 Inactivation of Wee1 kinase IEA Bos taurus 456216 R-BTA-156723 https://reactome.org/PathwayBrowser/#/R-BTA-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Bos taurus 456216 R-BTA-159101 https://reactome.org/PathwayBrowser/#/R-BTA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Bos taurus 456216 R-BTA-162657 https://reactome.org/PathwayBrowser/#/R-BTA-162657 Inactivation of Myt1 kinase IEA Bos taurus 456216 R-BTA-163010 https://reactome.org/PathwayBrowser/#/R-BTA-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Bos taurus 456216 R-BTA-163120 https://reactome.org/PathwayBrowser/#/R-BTA-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Bos taurus 456216 R-BTA-163215 https://reactome.org/PathwayBrowser/#/R-BTA-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Bos taurus 456216 R-BTA-1632857 https://reactome.org/PathwayBrowser/#/R-BTA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Bos taurus 456216 R-BTA-1638803 https://reactome.org/PathwayBrowser/#/R-BTA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Bos taurus 456216 R-BTA-1638845 https://reactome.org/PathwayBrowser/#/R-BTA-1638845 CERK phosphorylates CERA to form C1P IEA Bos taurus 456216 R-BTA-164832 https://reactome.org/PathwayBrowser/#/R-BTA-164832 ATPase synthesizes ATP IEA Bos taurus 456216 R-BTA-164840 https://reactome.org/PathwayBrowser/#/R-BTA-164840 ADP and Pi bind to ATPase IEA Bos taurus 456216 R-BTA-165162 https://reactome.org/PathwayBrowser/#/R-BTA-165162 Phosphorylation of TSC2 by PKB IEA Bos taurus 456216 R-BTA-165182 https://reactome.org/PathwayBrowser/#/R-BTA-165182 Phosphorylation of complexed TSC2 by PKB IEA Bos taurus 456216 R-BTA-165692 https://reactome.org/PathwayBrowser/#/R-BTA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Bos taurus 456216 R-BTA-165718 https://reactome.org/PathwayBrowser/#/R-BTA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Bos taurus 456216 R-BTA-165726 https://reactome.org/PathwayBrowser/#/R-BTA-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Bos taurus 456216 R-BTA-165758 https://reactome.org/PathwayBrowser/#/R-BTA-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Bos taurus 456216 R-BTA-165766 https://reactome.org/PathwayBrowser/#/R-BTA-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Bos taurus 456216 R-BTA-165777 https://reactome.org/PathwayBrowser/#/R-BTA-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Bos taurus 456216 R-BTA-166245 https://reactome.org/PathwayBrowser/#/R-BTA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Bos taurus 456216 R-BTA-1675773 https://reactome.org/PathwayBrowser/#/R-BTA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Bos taurus 456216 R-BTA-1675776 https://reactome.org/PathwayBrowser/#/R-BTA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Bos taurus 456216 R-BTA-1675780 https://reactome.org/PathwayBrowser/#/R-BTA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Bos taurus 456216 R-BTA-1675810 https://reactome.org/PathwayBrowser/#/R-BTA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Bos taurus 456216 R-BTA-1675813 https://reactome.org/PathwayBrowser/#/R-BTA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Bos taurus 456216 R-BTA-1675883 https://reactome.org/PathwayBrowser/#/R-BTA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Bos taurus 456216 R-BTA-1675928 https://reactome.org/PathwayBrowser/#/R-BTA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Bos taurus 456216 R-BTA-1675939 https://reactome.org/PathwayBrowser/#/R-BTA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Bos taurus 456216 R-BTA-1675961 https://reactome.org/PathwayBrowser/#/R-BTA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Bos taurus 456216 R-BTA-1675974 https://reactome.org/PathwayBrowser/#/R-BTA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Bos taurus 456216 R-BTA-1676024 https://reactome.org/PathwayBrowser/#/R-BTA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Bos taurus 456216 R-BTA-1676048 https://reactome.org/PathwayBrowser/#/R-BTA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Bos taurus 456216 R-BTA-1676082 https://reactome.org/PathwayBrowser/#/R-BTA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Bos taurus 456216 R-BTA-1676109 https://reactome.org/PathwayBrowser/#/R-BTA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Bos taurus 456216 R-BTA-1676134 https://reactome.org/PathwayBrowser/#/R-BTA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Bos taurus 456216 R-BTA-1676145 https://reactome.org/PathwayBrowser/#/R-BTA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Bos taurus 456216 R-BTA-1676185 https://reactome.org/PathwayBrowser/#/R-BTA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Bos taurus 456216 R-BTA-1676206 https://reactome.org/PathwayBrowser/#/R-BTA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Bos taurus 456216 R-BTA-1678944 https://reactome.org/PathwayBrowser/#/R-BTA-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Bos taurus 456216 R-BTA-168136 https://reactome.org/PathwayBrowser/#/R-BTA-168136 Activated JNKs phosphorylate c-JUN IEA Bos taurus 456216 R-BTA-168140 https://reactome.org/PathwayBrowser/#/R-BTA-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Bos taurus 456216 R-BTA-168162 https://reactome.org/PathwayBrowser/#/R-BTA-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Bos taurus 456216 R-BTA-169905 https://reactome.org/PathwayBrowser/#/R-BTA-169905 ARMS is phosphorylated by active TrkA receptor IEA Bos taurus 456216 R-BTA-170026 https://reactome.org/PathwayBrowser/#/R-BTA-170026 Protons are translocated from the intermembrane space to the matrix IEA Bos taurus 456216 R-BTA-170055 https://reactome.org/PathwayBrowser/#/R-BTA-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Bos taurus 456216 R-BTA-170070 https://reactome.org/PathwayBrowser/#/R-BTA-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Bos taurus 456216 R-BTA-170076 https://reactome.org/PathwayBrowser/#/R-BTA-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Bos taurus 456216 R-BTA-170087 https://reactome.org/PathwayBrowser/#/R-BTA-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Bos taurus 456216 R-BTA-170126 https://reactome.org/PathwayBrowser/#/R-BTA-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Bos taurus 456216 R-BTA-170843 https://reactome.org/PathwayBrowser/#/R-BTA-170843 TGFBR2 phosphorylates TGFBR1 IEA Bos taurus 456216 R-BTA-170868 https://reactome.org/PathwayBrowser/#/R-BTA-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Bos taurus 456216 R-BTA-170977 https://reactome.org/PathwayBrowser/#/R-BTA-170977 FRS2 is phosphorylated by active TrkA receptor IEA Bos taurus 456216 R-BTA-174079 https://reactome.org/PathwayBrowser/#/R-BTA-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Bos taurus 456216 R-BTA-174122 https://reactome.org/PathwayBrowser/#/R-BTA-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Bos taurus 456216 R-BTA-174164 https://reactome.org/PathwayBrowser/#/R-BTA-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Bos taurus 456216 R-BTA-174174 https://reactome.org/PathwayBrowser/#/R-BTA-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Bos taurus 456216 R-BTA-174251 https://reactome.org/PathwayBrowser/#/R-BTA-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Bos taurus 456216 R-BTA-174367 https://reactome.org/PathwayBrowser/#/R-BTA-174367 GCL ligates L-Glu to L-Cys IEA Bos taurus 456216 R-BTA-174389 https://reactome.org/PathwayBrowser/#/R-BTA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Bos taurus 456216 R-BTA-174394 https://reactome.org/PathwayBrowser/#/R-BTA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Bos taurus 456216 R-BTA-174438 https://reactome.org/PathwayBrowser/#/R-BTA-174438 Formation of the Flap Intermediate on the C-strand IEA Bos taurus 456216 R-BTA-174439 https://reactome.org/PathwayBrowser/#/R-BTA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Bos taurus 456216 R-BTA-176298 https://reactome.org/PathwayBrowser/#/R-BTA-176298 Activation of claspin IEA Bos taurus 456216 R-BTA-177275 https://reactome.org/PathwayBrowser/#/R-BTA-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Bos taurus 456216 R-BTA-177284 https://reactome.org/PathwayBrowser/#/R-BTA-177284 PKA phosphorylates PDE4B IEA Bos taurus 456216 R-BTA-177930 https://reactome.org/PathwayBrowser/#/R-BTA-177930 GAB1 phosphorylation by EGFR kinase IEA Bos taurus 456216 R-BTA-177933 https://reactome.org/PathwayBrowser/#/R-BTA-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Bos taurus 456216 R-BTA-177934 https://reactome.org/PathwayBrowser/#/R-BTA-177934 EGFR autophosphorylation IEA Bos taurus 456216 R-BTA-177937 https://reactome.org/PathwayBrowser/#/R-BTA-177937 Phosphorylation of EGFR by SRC kinase IEA Bos taurus 456216 R-BTA-177939 https://reactome.org/PathwayBrowser/#/R-BTA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Bos taurus 456216 R-BTA-182969 https://reactome.org/PathwayBrowser/#/R-BTA-182969 Phosphorylation of CBL (EGFR:CBL) IEA Bos taurus 456216 R-BTA-183058 https://reactome.org/PathwayBrowser/#/R-BTA-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Bos taurus 456216 R-BTA-1855153 https://reactome.org/PathwayBrowser/#/R-BTA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Bos taurus 456216 R-BTA-1855157 https://reactome.org/PathwayBrowser/#/R-BTA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Bos taurus 456216 R-BTA-1855158 https://reactome.org/PathwayBrowser/#/R-BTA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Bos taurus 456216 R-BTA-1855162 https://reactome.org/PathwayBrowser/#/R-BTA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Bos taurus 456216 R-BTA-1855169 https://reactome.org/PathwayBrowser/#/R-BTA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Bos taurus 456216 R-BTA-1855172 https://reactome.org/PathwayBrowser/#/R-BTA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Bos taurus 456216 R-BTA-1855176 https://reactome.org/PathwayBrowser/#/R-BTA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Bos taurus 456216 R-BTA-1855179 https://reactome.org/PathwayBrowser/#/R-BTA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Bos taurus 456216 R-BTA-1855181 https://reactome.org/PathwayBrowser/#/R-BTA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Bos taurus 456216 R-BTA-1855182 https://reactome.org/PathwayBrowser/#/R-BTA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Bos taurus 456216 R-BTA-1855185 https://reactome.org/PathwayBrowser/#/R-BTA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 456216 R-BTA-1855193 https://reactome.org/PathwayBrowser/#/R-BTA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Bos taurus 456216 R-BTA-1855194 https://reactome.org/PathwayBrowser/#/R-BTA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Bos taurus 456216 R-BTA-1855197 https://reactome.org/PathwayBrowser/#/R-BTA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Bos taurus 456216 R-BTA-1855206 https://reactome.org/PathwayBrowser/#/R-BTA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 456216 R-BTA-1855207 https://reactome.org/PathwayBrowser/#/R-BTA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Bos taurus 456216 R-BTA-1855216 https://reactome.org/PathwayBrowser/#/R-BTA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Bos taurus 456216 R-BTA-1855223 https://reactome.org/PathwayBrowser/#/R-BTA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Bos taurus 456216 R-BTA-1855224 https://reactome.org/PathwayBrowser/#/R-BTA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Bos taurus 456216 R-BTA-1855227 https://reactome.org/PathwayBrowser/#/R-BTA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Bos taurus 456216 R-BTA-1855228 https://reactome.org/PathwayBrowser/#/R-BTA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 456216 R-BTA-1855230 https://reactome.org/PathwayBrowser/#/R-BTA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Bos taurus 456216 R-BTA-1855233 https://reactome.org/PathwayBrowser/#/R-BTA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Bos taurus 456216 R-BTA-1861595 https://reactome.org/PathwayBrowser/#/R-BTA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Bos taurus 456216 R-BTA-186786 https://reactome.org/PathwayBrowser/#/R-BTA-186786 Autophosphorylation of PDGF beta receptors IEA Bos taurus 456216 R-BTA-186800 https://reactome.org/PathwayBrowser/#/R-BTA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-187520 https://reactome.org/PathwayBrowser/#/R-BTA-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Bos taurus 456216 R-BTA-187688 https://reactome.org/PathwayBrowser/#/R-BTA-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Bos taurus 456216 R-BTA-187916 https://reactome.org/PathwayBrowser/#/R-BTA-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Bos taurus 456216 R-BTA-187948 https://reactome.org/PathwayBrowser/#/R-BTA-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Bos taurus 456216 R-BTA-187949 https://reactome.org/PathwayBrowser/#/R-BTA-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Bos taurus 456216 R-BTA-187959 https://reactome.org/PathwayBrowser/#/R-BTA-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Bos taurus 456216 R-BTA-188350 https://reactome.org/PathwayBrowser/#/R-BTA-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Bos taurus 456216 R-BTA-188390 https://reactome.org/PathwayBrowser/#/R-BTA-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Bos taurus 456216 R-BTA-190326 https://reactome.org/PathwayBrowser/#/R-BTA-190326 Autocatalytic phosphorylation of FGFR4 IEA Bos taurus 456216 R-BTA-190385 https://reactome.org/PathwayBrowser/#/R-BTA-190385 Autocatalytic phosphorylation of FGFR3b IEA Bos taurus 456216 R-BTA-190388 https://reactome.org/PathwayBrowser/#/R-BTA-190388 Autocatalytic phosphorylation of FGFR3c IEA Bos taurus 456216 R-BTA-190408 https://reactome.org/PathwayBrowser/#/R-BTA-190408 Autocatalytic phosphorylation of FGFR2b IEA Bos taurus 456216 R-BTA-190413 https://reactome.org/PathwayBrowser/#/R-BTA-190413 Autocatalytic phosphorylation of FGFR2c IEA Bos taurus 456216 R-BTA-190427 https://reactome.org/PathwayBrowser/#/R-BTA-190427 Autocatalytic phosphorylation of FGFR1b IEA Bos taurus 456216 R-BTA-190429 https://reactome.org/PathwayBrowser/#/R-BTA-190429 Autocatalytic phosphorylation of FGFR1c IEA Bos taurus 456216 R-BTA-191062 https://reactome.org/PathwayBrowser/#/R-BTA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Bos taurus 456216 R-BTA-191380 https://reactome.org/PathwayBrowser/#/R-BTA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Bos taurus 456216 R-BTA-191414 https://reactome.org/PathwayBrowser/#/R-BTA-191414 MVD decarboxylates MVA5PP to IPPP IEA Bos taurus 456216 R-BTA-191422 https://reactome.org/PathwayBrowser/#/R-BTA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Bos taurus 456216 R-BTA-191636 https://reactome.org/PathwayBrowser/#/R-BTA-191636 Phosphorylation of Cx43 by c-src IEA Bos taurus 456216 R-BTA-193362 https://reactome.org/PathwayBrowser/#/R-BTA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-193703 https://reactome.org/PathwayBrowser/#/R-BTA-193703 IKKbeta is activated IEA Bos taurus 456216 R-BTA-193705 https://reactome.org/PathwayBrowser/#/R-BTA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Bos taurus 456216 R-BTA-194153 https://reactome.org/PathwayBrowser/#/R-BTA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-195275 https://reactome.org/PathwayBrowser/#/R-BTA-195275 Phosphorylation of APC component of the destruction complex IEA Bos taurus 456216 R-BTA-195283 https://reactome.org/PathwayBrowser/#/R-BTA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Bos taurus 456216 R-BTA-195287 https://reactome.org/PathwayBrowser/#/R-BTA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Bos taurus 456216 R-BTA-195300 https://reactome.org/PathwayBrowser/#/R-BTA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Bos taurus 456216 R-BTA-195318 https://reactome.org/PathwayBrowser/#/R-BTA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Bos taurus 456216 R-BTA-1963581 https://reactome.org/PathwayBrowser/#/R-BTA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Bos taurus 456216 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 456216 R-BTA-1963586 https://reactome.org/PathwayBrowser/#/R-BTA-1963586 SRC family kinases phosphorylate ERBB2 IEA Bos taurus 456216 R-BTA-196773 https://reactome.org/PathwayBrowser/#/R-BTA-196773 COASY phosphorylates DP-CoA IEA Bos taurus 456216 R-BTA-196857 https://reactome.org/PathwayBrowser/#/R-BTA-196857 PANK2 phosphorylates PanK IEA Bos taurus 456216 R-BTA-196964 https://reactome.org/PathwayBrowser/#/R-BTA-196964 RFK:Mg2+ phosphorylates RIB IEA Bos taurus 456216 R-BTA-197198 https://reactome.org/PathwayBrowser/#/R-BTA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Bos taurus 456216 R-BTA-197958 https://reactome.org/PathwayBrowser/#/R-BTA-197958 FPGS-2 transforms THF to THFPG IEA Bos taurus 456216 R-BTA-198266 https://reactome.org/PathwayBrowser/#/R-BTA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Bos taurus 456216 R-BTA-198314 https://reactome.org/PathwayBrowser/#/R-BTA-198314 DAG stimulates protein kinase C-delta IEA Bos taurus 456216 R-BTA-198669 https://reactome.org/PathwayBrowser/#/R-BTA-198669 p38MAPK phosphorylates MSK1 IEA Bos taurus 456216 R-BTA-198746 https://reactome.org/PathwayBrowser/#/R-BTA-198746 ERK1/2/5 activate RSK1/2/3 IEA Bos taurus 456216 R-BTA-198756 https://reactome.org/PathwayBrowser/#/R-BTA-198756 ERK1/2 phosphorylates MSK1 IEA Bos taurus 456216 R-BTA-199203 https://reactome.org/PathwayBrowser/#/R-BTA-199203 PANK1/3 phosphorylate PanK IEA Bos taurus 456216 R-BTA-199895 https://reactome.org/PathwayBrowser/#/R-BTA-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Bos taurus 456216 R-BTA-199910 https://reactome.org/PathwayBrowser/#/R-BTA-199910 MSK1 activates ATF1 IEA Bos taurus 456216 R-BTA-199917 https://reactome.org/PathwayBrowser/#/R-BTA-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Bos taurus 456216 R-BTA-199935 https://reactome.org/PathwayBrowser/#/R-BTA-199935 MSK1 activates CREB IEA Bos taurus 456216 R-BTA-200318 https://reactome.org/PathwayBrowser/#/R-BTA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Bos taurus 456216 R-BTA-200326 https://reactome.org/PathwayBrowser/#/R-BTA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Bos taurus 456216 R-BTA-200421 https://reactome.org/PathwayBrowser/#/R-BTA-200421 Activation of cytosolic AMPK by phosphorylation IEA Bos taurus 456216 R-BTA-200423 https://reactome.org/PathwayBrowser/#/R-BTA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Bos taurus 456216 R-BTA-200555 https://reactome.org/PathwayBrowser/#/R-BTA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Bos taurus 456216 R-BTA-200681 https://reactome.org/PathwayBrowser/#/R-BTA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Bos taurus 456216 R-BTA-200682 https://reactome.org/PathwayBrowser/#/R-BTA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Bos taurus 456216 R-BTA-200711 https://reactome.org/PathwayBrowser/#/R-BTA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Bos taurus 456216 R-BTA-201443 https://reactome.org/PathwayBrowser/#/R-BTA-201443 Type II receptor phosphorylates type I receptor IEA Bos taurus 456216 R-BTA-201476 https://reactome.org/PathwayBrowser/#/R-BTA-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Bos taurus 456216 R-BTA-201510 https://reactome.org/PathwayBrowser/#/R-BTA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Bos taurus 456216 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 456216 R-BTA-201677 https://reactome.org/PathwayBrowser/#/R-BTA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Bos taurus 456216 R-BTA-201717 https://reactome.org/PathwayBrowser/#/R-BTA-201717 CSNK2-mediated phosphorylation of DVL IEA Bos taurus 456216 R-BTA-202111 https://reactome.org/PathwayBrowser/#/R-BTA-202111 AKT1 phosphorylates eNOS IEA Bos taurus 456216 R-BTA-202165 https://reactome.org/PathwayBrowser/#/R-BTA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Bos taurus 456216 R-BTA-202168 https://reactome.org/PathwayBrowser/#/R-BTA-202168 Phosphorylation of ZAP-70 by Lck IEA Bos taurus 456216 R-BTA-202174 https://reactome.org/PathwayBrowser/#/R-BTA-202174 Activation of ZAP-70 IEA Bos taurus 456216 R-BTA-202216 https://reactome.org/PathwayBrowser/#/R-BTA-202216 Phosphorylation of SLP-76 IEA Bos taurus 456216 R-BTA-202222 https://reactome.org/PathwayBrowser/#/R-BTA-202222 Phosphorylation of PKC theta IEA Bos taurus 456216 R-BTA-202233 https://reactome.org/PathwayBrowser/#/R-BTA-202233 Inactivation of Lck by Csk IEA Bos taurus 456216 R-BTA-202245 https://reactome.org/PathwayBrowser/#/R-BTA-202245 Phosphorylation of TBSMs in LAT IEA Bos taurus 456216 R-BTA-202248 https://reactome.org/PathwayBrowser/#/R-BTA-202248 Phosphorylation of PLC-gamma1 IEA Bos taurus 456216 R-BTA-202291 https://reactome.org/PathwayBrowser/#/R-BTA-202291 Activation of Lck IEA Bos taurus 456216 R-BTA-202307 https://reactome.org/PathwayBrowser/#/R-BTA-202307 Change of PKC theta conformation IEA Bos taurus 456216 R-BTA-202365 https://reactome.org/PathwayBrowser/#/R-BTA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-202437 https://reactome.org/PathwayBrowser/#/R-BTA-202437 Phosphorylation of CARMA1 IEA Bos taurus 456216 R-BTA-202459 https://reactome.org/PathwayBrowser/#/R-BTA-202459 Phosphorylation of Bcl10 IEA Bos taurus 456216 R-BTA-202500 https://reactome.org/PathwayBrowser/#/R-BTA-202500 Activation of IKK complex IEA Bos taurus 456216 R-BTA-202510 https://reactome.org/PathwayBrowser/#/R-BTA-202510 Activation of TAK1-TAB2 complex IEA Bos taurus 456216 R-BTA-202541 https://reactome.org/PathwayBrowser/#/R-BTA-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Bos taurus 456216 R-BTA-2028284 https://reactome.org/PathwayBrowser/#/R-BTA-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Bos taurus 456216 R-BTA-2028555 https://reactome.org/PathwayBrowser/#/R-BTA-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Bos taurus 456216 R-BTA-2028583 https://reactome.org/PathwayBrowser/#/R-BTA-2028583 Phosphorylation of YAP by LATS2 IEA Bos taurus 456216 R-BTA-2028589 https://reactome.org/PathwayBrowser/#/R-BTA-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Bos taurus 456216 R-BTA-2028591 https://reactome.org/PathwayBrowser/#/R-BTA-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Bos taurus 456216 R-BTA-2028598 https://reactome.org/PathwayBrowser/#/R-BTA-2028598 Phosphorylation of YAP by LATS1 IEA Bos taurus 456216 R-BTA-2028629 https://reactome.org/PathwayBrowser/#/R-BTA-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Bos taurus 456216 R-BTA-2028635 https://reactome.org/PathwayBrowser/#/R-BTA-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Bos taurus 456216 R-BTA-2028661 https://reactome.org/PathwayBrowser/#/R-BTA-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Bos taurus 456216 R-BTA-2028670 https://reactome.org/PathwayBrowser/#/R-BTA-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Bos taurus 456216 R-BTA-2028673 https://reactome.org/PathwayBrowser/#/R-BTA-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Bos taurus 456216 R-BTA-2028675 https://reactome.org/PathwayBrowser/#/R-BTA-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Bos taurus 456216 R-BTA-2028679 https://reactome.org/PathwayBrowser/#/R-BTA-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Bos taurus 456216 R-BTA-2029268 https://reactome.org/PathwayBrowser/#/R-BTA-2029268 Phosphorylation and activation of PLCG IEA Bos taurus 456216 R-BTA-2029271 https://reactome.org/PathwayBrowser/#/R-BTA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-2029453 https://reactome.org/PathwayBrowser/#/R-BTA-2029453 Phosphorylation of VAV IEA Bos taurus 456216 R-BTA-2029454 https://reactome.org/PathwayBrowser/#/R-BTA-2029454 Autophosphorylation of PAK1 IEA Bos taurus 456216 R-BTA-2029459 https://reactome.org/PathwayBrowser/#/R-BTA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Bos taurus 456216 R-BTA-2029460 https://reactome.org/PathwayBrowser/#/R-BTA-2029460 PAK1 phosphorylates LIMK1 IEA Bos taurus 456216 R-BTA-2029469 https://reactome.org/PathwayBrowser/#/R-BTA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Bos taurus 456216 R-BTA-2029473 https://reactome.org/PathwayBrowser/#/R-BTA-2029473 Branching and elongation of mother and daughter filaments IEA Bos taurus 456216 R-BTA-2029476 https://reactome.org/PathwayBrowser/#/R-BTA-2029476 Role of myosins in phagosome formation IEA Bos taurus 456216 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 456216 R-BTA-2046087 https://reactome.org/PathwayBrowser/#/R-BTA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Bos taurus 456216 R-BTA-2046093 https://reactome.org/PathwayBrowser/#/R-BTA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Bos taurus 456216 R-BTA-205075 https://reactome.org/PathwayBrowser/#/R-BTA-205075 JNK phosphorylates BIM, BAD and other targets IEA Bos taurus 456216 R-BTA-205136 https://reactome.org/PathwayBrowser/#/R-BTA-205136 GTP-bound RAC contributes to JNK activation IEA Bos taurus 456216 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 456216 R-BTA-2060328 https://reactome.org/PathwayBrowser/#/R-BTA-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Bos taurus 456216 R-BTA-209087 https://reactome.org/PathwayBrowser/#/R-BTA-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Bos taurus 456216 R-BTA-210291 https://reactome.org/PathwayBrowser/#/R-BTA-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Bos taurus 456216 R-BTA-212710 https://reactome.org/PathwayBrowser/#/R-BTA-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Bos taurus 456216 R-BTA-2130194 https://reactome.org/PathwayBrowser/#/R-BTA-2130194 ABL phosphorylates WAVEs IEA Bos taurus 456216 R-BTA-216723 https://reactome.org/PathwayBrowser/#/R-BTA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Bos taurus 456216 R-BTA-216757 https://reactome.org/PathwayBrowser/#/R-BTA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Bos taurus 456216 R-BTA-2168079 https://reactome.org/PathwayBrowser/#/R-BTA-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Bos taurus 456216 R-BTA-2176475 https://reactome.org/PathwayBrowser/#/R-BTA-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Bos taurus 456216 R-BTA-2197690 https://reactome.org/PathwayBrowser/#/R-BTA-2197690 Detachment of WASP/WAVE IEA Bos taurus 456216 R-BTA-2197698 https://reactome.org/PathwayBrowser/#/R-BTA-2197698 Src phosphorylate WASP,N-WASP IEA Bos taurus 456216 R-BTA-2213248 https://reactome.org/PathwayBrowser/#/R-BTA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Bos taurus 456216 R-BTA-2214351 https://reactome.org/PathwayBrowser/#/R-BTA-2214351 PLK1 phosphorylates GORASP1 IEA Bos taurus 456216 R-BTA-2245218 https://reactome.org/PathwayBrowser/#/R-BTA-2245218 CDK1 phosphorylates PHF8 IEA Bos taurus 456216 R-BTA-2267372 https://reactome.org/PathwayBrowser/#/R-BTA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Bos taurus 456216 R-BTA-2294580 https://reactome.org/PathwayBrowser/#/R-BTA-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Bos taurus 456216 R-BTA-2294600 https://reactome.org/PathwayBrowser/#/R-BTA-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Bos taurus 456216 R-BTA-2316434 https://reactome.org/PathwayBrowser/#/R-BTA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-2396002 https://reactome.org/PathwayBrowser/#/R-BTA-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex IEA Bos taurus 456216 R-BTA-2396007 https://reactome.org/PathwayBrowser/#/R-BTA-2396007 IRF3 is phosphorylated by TBK1 IEA Bos taurus 456216 R-BTA-2404193 https://reactome.org/PathwayBrowser/#/R-BTA-2404193 IGF1R phosphorylates SHC1 IEA Bos taurus 456216 R-BTA-2404199 https://reactome.org/PathwayBrowser/#/R-BTA-2404199 IGF1,2:IGF1R autophosphorylates IEA Bos taurus 456216 R-BTA-2422927 https://reactome.org/PathwayBrowser/#/R-BTA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Bos taurus 456216 R-BTA-2424480 https://reactome.org/PathwayBrowser/#/R-BTA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-2424487 https://reactome.org/PathwayBrowser/#/R-BTA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Bos taurus 456216 R-BTA-2428926 https://reactome.org/PathwayBrowser/#/R-BTA-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Bos taurus 456216 R-BTA-2430535 https://reactome.org/PathwayBrowser/#/R-BTA-2430535 MASTL phosphorylates ENSA IEA Bos taurus 456216 R-BTA-2454208 https://reactome.org/PathwayBrowser/#/R-BTA-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Bos taurus 456216 R-BTA-2466068 https://reactome.org/PathwayBrowser/#/R-BTA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Bos taurus 456216 R-BTA-2466767 https://reactome.org/PathwayBrowser/#/R-BTA-2466767 NRPE is a substrate for Abca4 TAS Bos taurus 456216 R-BTA-2468287 https://reactome.org/PathwayBrowser/#/R-BTA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Bos taurus 456216 R-BTA-2468293 https://reactome.org/PathwayBrowser/#/R-BTA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Bos taurus 456216 R-BTA-2529020 https://reactome.org/PathwayBrowser/#/R-BTA-2529020 CK2 phosphorylates condensin I subunits IEA Bos taurus 456216 R-BTA-2562526 https://reactome.org/PathwayBrowser/#/R-BTA-2562526 PLK1 phosphorylates OPTN IEA Bos taurus 456216 R-BTA-2574840 https://reactome.org/PathwayBrowser/#/R-BTA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Bos taurus 456216 R-BTA-2581474 https://reactome.org/PathwayBrowser/#/R-BTA-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Bos taurus 456216 R-BTA-265682 https://reactome.org/PathwayBrowser/#/R-BTA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Bos taurus 456216 R-BTA-265783 https://reactome.org/PathwayBrowser/#/R-BTA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-266082 https://reactome.org/PathwayBrowser/#/R-BTA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Bos taurus 456216 R-BTA-2730833 https://reactome.org/PathwayBrowser/#/R-BTA-2730833 Phosphorylation of TEC kinases by p-SYK IEA Bos taurus 456216 R-BTA-2730835 https://reactome.org/PathwayBrowser/#/R-BTA-2730835 Autophosphorylation of PKC-theta IEA Bos taurus 456216 R-BTA-2730841 https://reactome.org/PathwayBrowser/#/R-BTA-2730841 Phosphorylation and activation of VAV IEA Bos taurus 456216 R-BTA-2730843 https://reactome.org/PathwayBrowser/#/R-BTA-2730843 Phosphorylation of LAT by p-SYK IEA Bos taurus 456216 R-BTA-2730851 https://reactome.org/PathwayBrowser/#/R-BTA-2730851 Phosphorylation of SLP-76 by p-SYK IEA Bos taurus 456216 R-BTA-2730856 https://reactome.org/PathwayBrowser/#/R-BTA-2730856 Autophosphorylation of PAK IEA Bos taurus 456216 R-BTA-2730858 https://reactome.org/PathwayBrowser/#/R-BTA-2730858 Autophosphorylation of BTK/ITK IEA Bos taurus 456216 R-BTA-2730862 https://reactome.org/PathwayBrowser/#/R-BTA-2730862 Autophosphorylation of LYN kinase IEA Bos taurus 456216 R-BTA-2730863 https://reactome.org/PathwayBrowser/#/R-BTA-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Bos taurus 456216 R-BTA-2730870 https://reactome.org/PathwayBrowser/#/R-BTA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Bos taurus 456216 R-BTA-2730876 https://reactome.org/PathwayBrowser/#/R-BTA-2730876 Phosphorylation of IKK-beta by TAK1 IEA Bos taurus 456216 R-BTA-2730882 https://reactome.org/PathwayBrowser/#/R-BTA-2730882 Phosphorylation of PKC-theta IEA Bos taurus 456216 R-BTA-2730884 https://reactome.org/PathwayBrowser/#/R-BTA-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Bos taurus 456216 R-BTA-2730886 https://reactome.org/PathwayBrowser/#/R-BTA-2730886 Phosphorylation of SHC by SYK kinase IEA Bos taurus 456216 R-BTA-2730896 https://reactome.org/PathwayBrowser/#/R-BTA-2730896 Phosphorylation of MEK4 by MEKK1 IEA Bos taurus 456216 R-BTA-2730900 https://reactome.org/PathwayBrowser/#/R-BTA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Bos taurus 456216 R-BTA-2984220 https://reactome.org/PathwayBrowser/#/R-BTA-2984220 CDK1:CCNB phosphorylates NEK9 IEA Bos taurus 456216 R-BTA-2984226 https://reactome.org/PathwayBrowser/#/R-BTA-2984226 PLK1 phosphorylates NEK9 IEA Bos taurus 456216 R-BTA-2984258 https://reactome.org/PathwayBrowser/#/R-BTA-2984258 NEK9 phosphorylates NEK6/NEK7 IEA Bos taurus 456216 R-BTA-2990880 https://reactome.org/PathwayBrowser/#/R-BTA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Bos taurus 456216 R-BTA-2990882 https://reactome.org/PathwayBrowser/#/R-BTA-2990882 CDK1 phosphorylates NUP98 IEA Bos taurus 456216 R-BTA-2993898 https://reactome.org/PathwayBrowser/#/R-BTA-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Bos taurus 456216 R-BTA-3000310 https://reactome.org/PathwayBrowser/#/R-BTA-3000310 AURKA phosphorylates PLK1 IEA Bos taurus 456216 R-BTA-3000327 https://reactome.org/PathwayBrowser/#/R-BTA-3000327 PLK1 phosphorylates BORA IEA Bos taurus 456216 R-BTA-3095901 https://reactome.org/PathwayBrowser/#/R-BTA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Bos taurus 456216 R-BTA-3132737 https://reactome.org/PathwayBrowser/#/R-BTA-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Bos taurus 456216 R-BTA-3222006 https://reactome.org/PathwayBrowser/#/R-BTA-3222006 STK11 (LKB1) phosphorylates NUAK1 IEA Bos taurus 456216 R-BTA-3222020 https://reactome.org/PathwayBrowser/#/R-BTA-3222020 NUAK1 phosphorylates TP53 IEA Bos taurus 456216 R-BTA-3228469 https://reactome.org/PathwayBrowser/#/R-BTA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Bos taurus 456216 R-BTA-3229102 https://reactome.org/PathwayBrowser/#/R-BTA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Bos taurus 456216 R-BTA-3238999 https://reactome.org/PathwayBrowser/#/R-BTA-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Bos taurus 456216 R-BTA-3239014 https://reactome.org/PathwayBrowser/#/R-BTA-3239014 MAPKAPK5 phosphorylates TP53 IEA Bos taurus 456216 R-BTA-3239019 https://reactome.org/PathwayBrowser/#/R-BTA-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Bos taurus 456216 R-BTA-3249371 https://reactome.org/PathwayBrowser/#/R-BTA-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Bos taurus 456216 R-BTA-3249379 https://reactome.org/PathwayBrowser/#/R-BTA-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Bos taurus 456216 R-BTA-3249390 https://reactome.org/PathwayBrowser/#/R-BTA-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Bos taurus 456216 R-BTA-3371422 https://reactome.org/PathwayBrowser/#/R-BTA-3371422 ATP hydrolysis by HSP70 IEA Bos taurus 456216 R-BTA-3371435 https://reactome.org/PathwayBrowser/#/R-BTA-3371435 Constitutive phosphorylation by GSK3 IEA Bos taurus 456216 R-BTA-3371503 https://reactome.org/PathwayBrowser/#/R-BTA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Bos taurus 456216 R-BTA-3371531 https://reactome.org/PathwayBrowser/#/R-BTA-3371531 Constitutive phosphorylation by pERK1/2 IEA Bos taurus 456216 R-BTA-349444 https://reactome.org/PathwayBrowser/#/R-BTA-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Bos taurus 456216 R-BTA-354073 https://reactome.org/PathwayBrowser/#/R-BTA-354073 Autophosphorylation of PTK2 at Y397 IEA Bos taurus 456216 R-BTA-354124 https://reactome.org/PathwayBrowser/#/R-BTA-354124 Phosphorylation of pPTK2 by SRC IEA Bos taurus 456216 R-BTA-372693 https://reactome.org/PathwayBrowser/#/R-BTA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Bos taurus 456216 R-BTA-373747 https://reactome.org/PathwayBrowser/#/R-BTA-373747 Phosphorylation of nephrin by FYN IEA Bos taurus 456216 R-BTA-373750 https://reactome.org/PathwayBrowser/#/R-BTA-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Bos taurus 456216 R-BTA-374664 https://reactome.org/PathwayBrowser/#/R-BTA-374664 Phosphorylation and activation of Ezrin IEA Bos taurus 456216 R-BTA-374701 https://reactome.org/PathwayBrowser/#/R-BTA-374701 Phosphorylation of DCC by Fyn IEA Bos taurus 456216 R-BTA-3769394 https://reactome.org/PathwayBrowser/#/R-BTA-3769394 AKT phosphorylates CBY1 IEA Bos taurus 456216 R-BTA-3772435 https://reactome.org/PathwayBrowser/#/R-BTA-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Bos taurus 456216 R-BTA-3772436 https://reactome.org/PathwayBrowser/#/R-BTA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Bos taurus 456216 R-BTA-377640 https://reactome.org/PathwayBrowser/#/R-BTA-377640 Autophosphorylation of SRC IEA Bos taurus 456216 R-BTA-3788705 https://reactome.org/PathwayBrowser/#/R-BTA-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Bos taurus 456216 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 456216 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 456216 R-BTA-380272 https://reactome.org/PathwayBrowser/#/R-BTA-380272 Plk1-mediated phosphorylation of Nlp IEA Bos taurus 456216 R-BTA-380278 https://reactome.org/PathwayBrowser/#/R-BTA-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Bos taurus 456216 R-BTA-380780 https://reactome.org/PathwayBrowser/#/R-BTA-380780 Activation of Src IEA Bos taurus 456216 R-BTA-380927 https://reactome.org/PathwayBrowser/#/R-BTA-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Bos taurus 456216 R-BTA-381091 https://reactome.org/PathwayBrowser/#/R-BTA-381091 IRE1 dimer autophosphorylates IEA Bos taurus 456216 R-BTA-381111 https://reactome.org/PathwayBrowser/#/R-BTA-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Bos taurus 456216 R-BTA-382560 https://reactome.org/PathwayBrowser/#/R-BTA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Bos taurus 456216 R-BTA-382575 https://reactome.org/PathwayBrowser/#/R-BTA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Bos taurus 456216 R-BTA-383190 https://reactome.org/PathwayBrowser/#/R-BTA-383190 HCO3- transport through ion channel IEA Bos taurus 456216 R-BTA-3857329 https://reactome.org/PathwayBrowser/#/R-BTA-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Bos taurus 456216 R-BTA-388831 https://reactome.org/PathwayBrowser/#/R-BTA-388831 Phosphorylation of CD28 IEA Bos taurus 456216 R-BTA-388833 https://reactome.org/PathwayBrowser/#/R-BTA-388833 Phosphorylation of CTLA-4 IEA Bos taurus 456216 R-BTA-389083 https://reactome.org/PathwayBrowser/#/R-BTA-389083 Autophosphorylation of PDGF alpha receptors IEA Bos taurus 456216 R-BTA-389086 https://reactome.org/PathwayBrowser/#/R-BTA-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Bos taurus 456216 R-BTA-389158 https://reactome.org/PathwayBrowser/#/R-BTA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-389354 https://reactome.org/PathwayBrowser/#/R-BTA-389354 Activation of Vav1 IEA Bos taurus 456216 R-BTA-389762 https://reactome.org/PathwayBrowser/#/R-BTA-389762 Phosphorylation of PD-1 IEA Bos taurus 456216 R-BTA-390593 https://reactome.org/PathwayBrowser/#/R-BTA-390593 ATP Hydrolysis By Myosin IEA Bos taurus 456216 R-BTA-390597 https://reactome.org/PathwayBrowser/#/R-BTA-390597 Release Of ADP From Myosin IEA Bos taurus 456216 R-BTA-391266 https://reactome.org/PathwayBrowser/#/R-BTA-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Bos taurus 456216 R-BTA-392187 https://reactome.org/PathwayBrowser/#/R-BTA-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Bos taurus 456216 R-BTA-392195 https://reactome.org/PathwayBrowser/#/R-BTA-392195 Gi activation by P2Y purinoceptor 12 IEA Bos taurus 456216 R-BTA-392202 https://reactome.org/PathwayBrowser/#/R-BTA-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Bos taurus 456216 R-BTA-392300 https://reactome.org/PathwayBrowser/#/R-BTA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-392530 https://reactome.org/PathwayBrowser/#/R-BTA-392530 p-S400-Cot phosphorylates NIK IEA Bos taurus 456216 R-BTA-3928578 https://reactome.org/PathwayBrowser/#/R-BTA-3928578 EPH receptors autophosphorylate IEA Bos taurus 456216 R-BTA-3928604 https://reactome.org/PathwayBrowser/#/R-BTA-3928604 SFKs phosphorylate VAV2,3 IEA Bos taurus 456216 R-BTA-3928620 https://reactome.org/PathwayBrowser/#/R-BTA-3928620 PAK1 autophosphorylates IEA Bos taurus 456216 R-BTA-3928625 https://reactome.org/PathwayBrowser/#/R-BTA-3928625 PAKs autophosphorylate IEA Bos taurus 456216 R-BTA-3928640 https://reactome.org/PathwayBrowser/#/R-BTA-3928640 PAKs phosphorylate MLC IEA Bos taurus 456216 R-BTA-399939 https://reactome.org/PathwayBrowser/#/R-BTA-399939 Autophosphorylation of PAK IEA Bos taurus 456216 R-BTA-399944 https://reactome.org/PathwayBrowser/#/R-BTA-399944 Phosphorylation of CRMPs by Cdk5 IEA Bos taurus 456216 R-BTA-399947 https://reactome.org/PathwayBrowser/#/R-BTA-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Bos taurus 456216 R-BTA-399951 https://reactome.org/PathwayBrowser/#/R-BTA-399951 Phosphorylation of CRMPs by GSK3beta IEA Bos taurus 456216 R-BTA-399952 https://reactome.org/PathwayBrowser/#/R-BTA-399952 Phosphorylation of LIMK-1 by PAK IEA Bos taurus 456216 R-BTA-4085028 https://reactome.org/PathwayBrowser/#/R-BTA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Bos taurus 456216 R-BTA-4086410 https://reactome.org/PathwayBrowser/#/R-BTA-4086410 CDK1 phosphorylates BORA IEA Bos taurus 456216 R-BTA-4088024 https://reactome.org/PathwayBrowser/#/R-BTA-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Bos taurus 456216 R-BTA-4088134 https://reactome.org/PathwayBrowser/#/R-BTA-4088134 PLK1 phosphorylates FOXM1 IEA Bos taurus 456216 R-BTA-4093332 https://reactome.org/PathwayBrowser/#/R-BTA-4093332 p-EPHB phosphorylates SDC2 IEA Bos taurus 456216 R-BTA-416320 https://reactome.org/PathwayBrowser/#/R-BTA-416320 Trafficking of GluR1-containing AMPA receptors IEA Bos taurus 456216 R-BTA-416639 https://reactome.org/PathwayBrowser/#/R-BTA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Bos taurus 456216 R-BTA-416985 https://reactome.org/PathwayBrowser/#/R-BTA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Bos taurus 456216 R-BTA-417829 https://reactome.org/PathwayBrowser/#/R-BTA-417829 P2RY12 binds ADP IEA Bos taurus 456216 R-BTA-417908 https://reactome.org/PathwayBrowser/#/R-BTA-417908 P2RY1 binds ADP IEA Bos taurus 456216 R-BTA-418576 https://reactome.org/PathwayBrowser/#/R-BTA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Bos taurus 456216 R-BTA-418845 https://reactome.org/PathwayBrowser/#/R-BTA-418845 Activation of caspase-3 IEA Bos taurus 456216 R-BTA-419644 https://reactome.org/PathwayBrowser/#/R-BTA-419644 Transphosphorylation of pLIMK1 IEA Bos taurus 456216 R-BTA-419646 https://reactome.org/PathwayBrowser/#/R-BTA-419646 SEMA4D interacts with Plexin-B1:Met IEA Bos taurus 456216 R-BTA-421007 https://reactome.org/PathwayBrowser/#/R-BTA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Bos taurus 456216 R-BTA-426240 https://reactome.org/PathwayBrowser/#/R-BTA-426240 DAG kinase produces phosphatidic acid from DAG IEA Bos taurus 456216 R-BTA-428273 https://reactome.org/PathwayBrowser/#/R-BTA-428273 SPHK1 phosphorylates sphingoid IEA Bos taurus 456216 R-BTA-428888 https://reactome.org/PathwayBrowser/#/R-BTA-428888 Phosphorylation of ROBO1 by ABL kinase IEA Bos taurus 456216 R-BTA-428941 https://reactome.org/PathwayBrowser/#/R-BTA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Bos taurus 456216 R-BTA-428961 https://reactome.org/PathwayBrowser/#/R-BTA-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Bos taurus 456216 R-BTA-429016 https://reactome.org/PathwayBrowser/#/R-BTA-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Bos taurus 456216 R-BTA-429157 https://reactome.org/PathwayBrowser/#/R-BTA-429157 ABCC4 accumulation of dense granule contents IEA Bos taurus 456216 R-BTA-429441 https://reactome.org/PathwayBrowser/#/R-BTA-429441 SYK activation by SRC IEA Bos taurus 456216 R-BTA-429449 https://reactome.org/PathwayBrowser/#/R-BTA-429449 Syk activation leads to SLP-76 activation IEA Bos taurus 456216 R-BTA-429698 https://reactome.org/PathwayBrowser/#/R-BTA-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Bos taurus 456216 R-BTA-429714 https://reactome.org/PathwayBrowser/#/R-BTA-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Bos taurus 456216 R-BTA-432129 https://reactome.org/PathwayBrowser/#/R-BTA-432129 FGR binds and phosphorylates LRP8 IEA Bos taurus 456216 R-BTA-432148 https://reactome.org/PathwayBrowser/#/R-BTA-432148 Fgr may phosphorylate p38 MAPK IEA Bos taurus 456216 R-BTA-432232 https://reactome.org/PathwayBrowser/#/R-BTA-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Bos taurus 456216 R-BTA-4332358 https://reactome.org/PathwayBrowser/#/R-BTA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Bos taurus 456216 R-BTA-4332363 https://reactome.org/PathwayBrowser/#/R-BTA-4332363 Autophosphorylation and activation of CAMK2 IEA Bos taurus 456216 R-BTA-434836 https://reactome.org/PathwayBrowser/#/R-BTA-434836 Syk/Lck phosphorylate LAT IEA Bos taurus 456216 R-BTA-435244 https://reactome.org/PathwayBrowser/#/R-BTA-435244 PECAM1 is phosphorylated IEA Bos taurus 456216 R-BTA-437162 https://reactome.org/PathwayBrowser/#/R-BTA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-4411383 https://reactome.org/PathwayBrowser/#/R-BTA-4411383 NLK phosphorylates TCF/LEF IEA Bos taurus 456216 R-BTA-4411402 https://reactome.org/PathwayBrowser/#/R-BTA-4411402 Activation of NLK IEA Bos taurus 456216 R-BTA-4420117 https://reactome.org/PathwayBrowser/#/R-BTA-4420117 VEGFR2 autophosphorylates IEA Bos taurus 456216 R-BTA-4420121 https://reactome.org/PathwayBrowser/#/R-BTA-4420121 SFKs phosphorylate PLCG1 IEA Bos taurus 456216 R-BTA-4420128 https://reactome.org/PathwayBrowser/#/R-BTA-4420128 SRC-1 phosphorylates SHB IEA Bos taurus 456216 R-BTA-4420206 https://reactome.org/PathwayBrowser/#/R-BTA-4420206 Phosphorylation of SRC-1 IEA Bos taurus 456216 R-BTA-442724 https://reactome.org/PathwayBrowser/#/R-BTA-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Bos taurus 456216 R-BTA-442749 https://reactome.org/PathwayBrowser/#/R-BTA-442749 CaMKK autophosphorylates in the nucleus IEA Bos taurus 456216 R-BTA-445072 https://reactome.org/PathwayBrowser/#/R-BTA-445072 Interaction of PAK1 with Rac1-GTP IEA Bos taurus 456216 R-BTA-445079 https://reactome.org/PathwayBrowser/#/R-BTA-445079 Phosphorylation of L1 by ERK IEA Bos taurus 456216 R-BTA-445699 https://reactome.org/PathwayBrowser/#/R-BTA-445699 ATP Hydrolysis By Myosin IEA Bos taurus 456216 R-BTA-445705 https://reactome.org/PathwayBrowser/#/R-BTA-445705 Release Of ADP From Myosin IEA Bos taurus 456216 R-BTA-445813 https://reactome.org/PathwayBrowser/#/R-BTA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Bos taurus 456216 R-BTA-446634 https://reactome.org/PathwayBrowser/#/R-BTA-446634 IRAK4 is activated by autophosphorylation IEA Bos taurus 456216 R-BTA-446694 https://reactome.org/PathwayBrowser/#/R-BTA-446694 IRAK4 phosphorylates IRAK1 IEA Bos taurus 456216 R-BTA-446701 https://reactome.org/PathwayBrowser/#/R-BTA-446701 IRAK4-activated IRAK1 autophosphorylates IEA Bos taurus 456216 R-BTA-447074 https://reactome.org/PathwayBrowser/#/R-BTA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Bos taurus 456216 R-BTA-448955 https://reactome.org/PathwayBrowser/#/R-BTA-448955 Phosphorylation of MEF2 proteins by p38 IEA Bos taurus 456216 R-BTA-450222 https://reactome.org/PathwayBrowser/#/R-BTA-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Bos taurus 456216 R-BTA-450325 https://reactome.org/PathwayBrowser/#/R-BTA-450325 c-FOS activation by phospho ERK1/2 IEA Bos taurus 456216 R-BTA-450333 https://reactome.org/PathwayBrowser/#/R-BTA-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Bos taurus 456216 R-BTA-450337 https://reactome.org/PathwayBrowser/#/R-BTA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Bos taurus 456216 R-BTA-450346 https://reactome.org/PathwayBrowser/#/R-BTA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Bos taurus 456216 R-BTA-450463 https://reactome.org/PathwayBrowser/#/R-BTA-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Bos taurus 456216 R-BTA-450474 https://reactome.org/PathwayBrowser/#/R-BTA-450474 MK2 phosphorylates BRF1 IEA Bos taurus 456216 R-BTA-450533 https://reactome.org/PathwayBrowser/#/R-BTA-450533 PKCdelta phosphorylates HuR IEA Bos taurus 456216 R-BTA-450827 https://reactome.org/PathwayBrowser/#/R-BTA-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Bos taurus 456216 R-BTA-451942 https://reactome.org/PathwayBrowser/#/R-BTA-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Bos taurus 456216 R-BTA-452097 https://reactome.org/PathwayBrowser/#/R-BTA-452097 Recruited STAT5 is phosphorylated IEA Bos taurus 456216 R-BTA-452100 https://reactome.org/PathwayBrowser/#/R-BTA-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Bos taurus 456216 R-BTA-452122 https://reactome.org/PathwayBrowser/#/R-BTA-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Bos taurus 456216 R-BTA-453200 https://reactome.org/PathwayBrowser/#/R-BTA-453200 SYK autophosphorylates IEA Bos taurus 456216 R-BTA-4793911 https://reactome.org/PathwayBrowser/#/R-BTA-4793911 MAPKAPK2 phosphorylates HSF1 IEA Bos taurus 456216 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 456216 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 456216 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 456216 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 456216 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 456216 R-BTA-504054 https://reactome.org/PathwayBrowser/#/R-BTA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Bos taurus 456216 R-BTA-508040 https://reactome.org/PathwayBrowser/#/R-BTA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Bos taurus 456216 R-BTA-5082387 https://reactome.org/PathwayBrowser/#/R-BTA-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Bos taurus 456216 R-BTA-5082405 https://reactome.org/PathwayBrowser/#/R-BTA-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Bos taurus 456216 R-BTA-508282 https://reactome.org/PathwayBrowser/#/R-BTA-508282 SYK is a substrate for JAK1 IEA Bos taurus 456216 R-BTA-508308 https://reactome.org/PathwayBrowser/#/R-BTA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Bos taurus 456216 R-BTA-5138432 https://reactome.org/PathwayBrowser/#/R-BTA-5138432 DVL2 is phosphorylated by PKC IEA Bos taurus 456216 R-BTA-5195402 https://reactome.org/PathwayBrowser/#/R-BTA-5195402 CDK1 phosphorylates LPIN IEA Bos taurus 456216 R-BTA-5213464 https://reactome.org/PathwayBrowser/#/R-BTA-5213464 RIPK1 is phosphorylated IEA Bos taurus 456216 R-BTA-5213466 https://reactome.org/PathwayBrowser/#/R-BTA-5213466 RIPK3 is phosphorylated IEA Bos taurus 456216 R-BTA-5218640 https://reactome.org/PathwayBrowser/#/R-BTA-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Bos taurus 456216 R-BTA-5218642 https://reactome.org/PathwayBrowser/#/R-BTA-5218642 PTK2 autophosphorylates IEA Bos taurus 456216 R-BTA-5218804 https://reactome.org/PathwayBrowser/#/R-BTA-5218804 p38 MAPK activation by VEGFR IEA Bos taurus 456216 R-BTA-5218805 https://reactome.org/PathwayBrowser/#/R-BTA-5218805 PKC autophosphorylates IEA Bos taurus 456216 R-BTA-5218806 https://reactome.org/PathwayBrowser/#/R-BTA-5218806 FYN autophosphorylates IEA Bos taurus 456216 R-BTA-5218809 https://reactome.org/PathwayBrowser/#/R-BTA-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Bos taurus 456216 R-BTA-5218812 https://reactome.org/PathwayBrowser/#/R-BTA-5218812 FYN phosphorylates PAK2 IEA Bos taurus 456216 R-BTA-5218814 https://reactome.org/PathwayBrowser/#/R-BTA-5218814 PAK2 autophorylates IEA Bos taurus 456216 R-BTA-5218819 https://reactome.org/PathwayBrowser/#/R-BTA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-5218820 https://reactome.org/PathwayBrowser/#/R-BTA-5218820 Src kinases phosphorylate VAV IEA Bos taurus 456216 R-BTA-5218821 https://reactome.org/PathwayBrowser/#/R-BTA-5218821 PDK1 phosphorylates PKC IEA Bos taurus 456216 R-BTA-5218823 https://reactome.org/PathwayBrowser/#/R-BTA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Bos taurus 456216 R-BTA-5218826 https://reactome.org/PathwayBrowser/#/R-BTA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Bos taurus 456216 R-BTA-5218830 https://reactome.org/PathwayBrowser/#/R-BTA-5218830 SRC-1 phosphorylates PTK2-beta IEA Bos taurus 456216 R-BTA-5218845 https://reactome.org/PathwayBrowser/#/R-BTA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Bos taurus 456216 R-BTA-5218851 https://reactome.org/PathwayBrowser/#/R-BTA-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Bos taurus 456216 R-BTA-5218854 https://reactome.org/PathwayBrowser/#/R-BTA-5218854 p-Y420-FYN is phosphorylated on S21 IEA Bos taurus 456216 R-BTA-5218906 https://reactome.org/PathwayBrowser/#/R-BTA-5218906 RIPK3 phosphorylates MLKL IEA Bos taurus 456216 R-BTA-5218916 https://reactome.org/PathwayBrowser/#/R-BTA-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Bos taurus 456216 R-BTA-5223313 https://reactome.org/PathwayBrowser/#/R-BTA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Bos taurus 456216 R-BTA-5223317 https://reactome.org/PathwayBrowser/#/R-BTA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Bos taurus 456216 R-BTA-5229194 https://reactome.org/PathwayBrowser/#/R-BTA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Bos taurus 456216 R-BTA-5229343 https://reactome.org/PathwayBrowser/#/R-BTA-5229343 AXIN is phosphorylated in the destruction complex IEA Bos taurus 456216 R-BTA-5244669 https://reactome.org/PathwayBrowser/#/R-BTA-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Bos taurus 456216 R-BTA-5251955 https://reactome.org/PathwayBrowser/#/R-BTA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Bos taurus 456216 R-BTA-5251959 https://reactome.org/PathwayBrowser/#/R-BTA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Bos taurus 456216 R-BTA-5251989 https://reactome.org/PathwayBrowser/#/R-BTA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Bos taurus 456216 R-BTA-5252079 https://reactome.org/PathwayBrowser/#/R-BTA-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Bos taurus 456216 R-BTA-5357429 https://reactome.org/PathwayBrowser/#/R-BTA-5357429 AXL autophosphorylates on Y779 and Y821 IEA Bos taurus 456216 R-BTA-5357472 https://reactome.org/PathwayBrowser/#/R-BTA-5357472 PAK1-3 autophosphorylates IEA Bos taurus 456216 R-BTA-5357477 https://reactome.org/PathwayBrowser/#/R-BTA-5357477 PAK1-3 phosphorylates VE-cadherin IEA Bos taurus 456216 R-BTA-5357831 https://reactome.org/PathwayBrowser/#/R-BTA-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Bos taurus 456216 R-BTA-5358513 https://reactome.org/PathwayBrowser/#/R-BTA-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Bos taurus 456216 R-BTA-5358525 https://reactome.org/PathwayBrowser/#/R-BTA-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Bos taurus 456216 R-BTA-5358912 https://reactome.org/PathwayBrowser/#/R-BTA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Bos taurus 456216 R-BTA-5362459 https://reactome.org/PathwayBrowser/#/R-BTA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Bos taurus 456216 R-BTA-5444511 https://reactome.org/PathwayBrowser/#/R-BTA-5444511 Formation of MSH2:MSH3 Complex IEA Bos taurus 456216 R-BTA-5444516 https://reactome.org/PathwayBrowser/#/R-BTA-5444516 Formation of MSH2:MSH6 Complex IEA Bos taurus 456216 R-BTA-5607722 https://reactome.org/PathwayBrowser/#/R-BTA-5607722 Active NIK phosphorylates IKKA dimer IEA Bos taurus 456216 R-BTA-5607726 https://reactome.org/PathwayBrowser/#/R-BTA-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Bos taurus 456216 R-BTA-5607732 https://reactome.org/PathwayBrowser/#/R-BTA-5607732 K63polyUb-TAK1 autophosphorylates IEA Bos taurus 456216 R-BTA-5607740 https://reactome.org/PathwayBrowser/#/R-BTA-5607740 PKC-delta phosphorylates CARD9 IEA Bos taurus 456216 R-BTA-5607742 https://reactome.org/PathwayBrowser/#/R-BTA-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Bos taurus 456216 R-BTA-5607750 https://reactome.org/PathwayBrowser/#/R-BTA-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Bos taurus 456216 R-BTA-5610720 https://reactome.org/PathwayBrowser/#/R-BTA-5610720 PKA phosphorylates GLI3 IEA Bos taurus 456216 R-BTA-5610722 https://reactome.org/PathwayBrowser/#/R-BTA-5610722 CK1 phosphorylates p-GLI3 IEA Bos taurus 456216 R-BTA-5610732 https://reactome.org/PathwayBrowser/#/R-BTA-5610732 GSK3 phosphorylates p-GLI3 IEA Bos taurus 456216 R-BTA-5617182 https://reactome.org/PathwayBrowser/#/R-BTA-5617182 PRKACA phosphorylates PLN IEA Bos taurus 456216 R-BTA-5618085 https://reactome.org/PathwayBrowser/#/R-BTA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Bos taurus 456216 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 456216 R-BTA-5618098 https://reactome.org/PathwayBrowser/#/R-BTA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Bos taurus 456216 R-BTA-5618105 https://reactome.org/PathwayBrowser/#/R-BTA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Bos taurus 456216 R-BTA-5618107 https://reactome.org/PathwayBrowser/#/R-BTA-5618107 ATP binding to HSP90 triggers conformation change IEA Bos taurus 456216 R-BTA-5618110 https://reactome.org/PathwayBrowser/#/R-BTA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Bos taurus 456216 R-BTA-5621355 https://reactome.org/PathwayBrowser/#/R-BTA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Bos taurus 456216 R-BTA-5621363 https://reactome.org/PathwayBrowser/#/R-BTA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Bos taurus 456216 R-BTA-5621370 https://reactome.org/PathwayBrowser/#/R-BTA-5621370 SYK autophosphorylates IEA Bos taurus 456216 R-BTA-5623667 https://reactome.org/PathwayBrowser/#/R-BTA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Bos taurus 456216 R-BTA-5624473 https://reactome.org/PathwayBrowser/#/R-BTA-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Bos taurus 456216 R-BTA-5625784 https://reactome.org/PathwayBrowser/#/R-BTA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Bos taurus 456216 R-BTA-5627775 https://reactome.org/PathwayBrowser/#/R-BTA-5627775 Autophosphorylation of PAK1,2,3 IEA Bos taurus 456216 R-BTA-5635842 https://reactome.org/PathwayBrowser/#/R-BTA-5635842 ULK3 phosphorylates GLI IEA Bos taurus 456216 R-BTA-5654147 https://reactome.org/PathwayBrowser/#/R-BTA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Bos taurus 456216 R-BTA-5654149 https://reactome.org/PathwayBrowser/#/R-BTA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Bos taurus 456216 R-BTA-5654151 https://reactome.org/PathwayBrowser/#/R-BTA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Bos taurus 456216 R-BTA-5654222 https://reactome.org/PathwayBrowser/#/R-BTA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Bos taurus 456216 R-BTA-5654397 https://reactome.org/PathwayBrowser/#/R-BTA-5654397 Activated FGFR2 phosphorylates FRS2 IEA Bos taurus 456216 R-BTA-5654407 https://reactome.org/PathwayBrowser/#/R-BTA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Bos taurus 456216 R-BTA-5654408 https://reactome.org/PathwayBrowser/#/R-BTA-5654408 Activated FGFR3 phosphorylates FRS2 IEA Bos taurus 456216 R-BTA-5654418 https://reactome.org/PathwayBrowser/#/R-BTA-5654418 Activated FGFR4 phosphorylates FRS2 IEA Bos taurus 456216 R-BTA-5654428 https://reactome.org/PathwayBrowser/#/R-BTA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Bos taurus 456216 R-BTA-5654560 https://reactome.org/PathwayBrowser/#/R-BTA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Bos taurus 456216 R-BTA-5654562 https://reactome.org/PathwayBrowser/#/R-BTA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Bos taurus 456216 R-BTA-5654565 https://reactome.org/PathwayBrowser/#/R-BTA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Bos taurus 456216 R-BTA-5654566 https://reactome.org/PathwayBrowser/#/R-BTA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Bos taurus 456216 R-BTA-5654575 https://reactome.org/PathwayBrowser/#/R-BTA-5654575 Activated FGFR1 phosphorylates FRS2 IEA Bos taurus 456216 R-BTA-5654578 https://reactome.org/PathwayBrowser/#/R-BTA-5654578 Activated FGFR1 phosphorylates FRS3 IEA Bos taurus 456216 R-BTA-5654582 https://reactome.org/PathwayBrowser/#/R-BTA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Bos taurus 456216 R-BTA-5654587 https://reactome.org/PathwayBrowser/#/R-BTA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Bos taurus 456216 R-BTA-5654605 https://reactome.org/PathwayBrowser/#/R-BTA-5654605 Activated FGFR2 phosphorylates FRS3 IEA Bos taurus 456216 R-BTA-5654607 https://reactome.org/PathwayBrowser/#/R-BTA-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Bos taurus 456216 R-BTA-5654628 https://reactome.org/PathwayBrowser/#/R-BTA-5654628 Activated FGFR3 phosphorylates FRS3 IEA Bos taurus 456216 R-BTA-5654631 https://reactome.org/PathwayBrowser/#/R-BTA-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Bos taurus 456216 R-BTA-5654634 https://reactome.org/PathwayBrowser/#/R-BTA-5654634 Activated FGFR3 phosphorylates SHC1 IEA Bos taurus 456216 R-BTA-5654653 https://reactome.org/PathwayBrowser/#/R-BTA-5654653 Activated FGFR4 phosphorylates FRS3 IEA Bos taurus 456216 R-BTA-5654655 https://reactome.org/PathwayBrowser/#/R-BTA-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Bos taurus 456216 R-BTA-5654690 https://reactome.org/PathwayBrowser/#/R-BTA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-5654692 https://reactome.org/PathwayBrowser/#/R-BTA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-5654697 https://reactome.org/PathwayBrowser/#/R-BTA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-5654701 https://reactome.org/PathwayBrowser/#/R-BTA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-5654705 https://reactome.org/PathwayBrowser/#/R-BTA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-5654709 https://reactome.org/PathwayBrowser/#/R-BTA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-5654714 https://reactome.org/PathwayBrowser/#/R-BTA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-5654717 https://reactome.org/PathwayBrowser/#/R-BTA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-5654989 https://reactome.org/PathwayBrowser/#/R-BTA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Bos taurus 456216 R-BTA-5662466 https://reactome.org/PathwayBrowser/#/R-BTA-5662466 XYLB phosphorylates D-xylulose IEA Bos taurus 456216 R-BTA-5665868 https://reactome.org/PathwayBrowser/#/R-BTA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Bos taurus 456216 R-BTA-5666160 https://reactome.org/PathwayBrowser/#/R-BTA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Bos taurus 456216 R-BTA-5668545 https://reactome.org/PathwayBrowser/#/R-BTA-5668545 NIK autophosphorylates on T559 IEA Bos taurus 456216 R-BTA-5668932 https://reactome.org/PathwayBrowser/#/R-BTA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Bos taurus 456216 R-BTA-5668947 https://reactome.org/PathwayBrowser/#/R-BTA-5668947 PAK1 phosphorylates myosin phosphatase IEA Bos taurus 456216 R-BTA-5668984 https://reactome.org/PathwayBrowser/#/R-BTA-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Bos taurus 456216 R-BTA-5669250 https://reactome.org/PathwayBrowser/#/R-BTA-5669250 PAK1 phosphorylates FLNA IEA Bos taurus 456216 R-BTA-5671749 https://reactome.org/PathwayBrowser/#/R-BTA-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Bos taurus 456216 R-BTA-5671763 https://reactome.org/PathwayBrowser/#/R-BTA-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Bos taurus 456216 R-BTA-5672008 https://reactome.org/PathwayBrowser/#/R-BTA-5672008 Thr-180 of ULK1 is phosphorylated IEA Bos taurus 456216 R-BTA-5672010 https://reactome.org/PathwayBrowser/#/R-BTA-5672010 Active MTORC1 phosphorylates ULK1 IEA Bos taurus 456216 R-BTA-5672012 https://reactome.org/PathwayBrowser/#/R-BTA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Bos taurus 456216 R-BTA-5672027 https://reactome.org/PathwayBrowser/#/R-BTA-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Bos taurus 456216 R-BTA-5672828 https://reactome.org/PathwayBrowser/#/R-BTA-5672828 mTORC1 phosphorylates AKT1S1 IEA Bos taurus 456216 R-BTA-5672948 https://reactome.org/PathwayBrowser/#/R-BTA-5672948 MARK3 phosphorylates KSR1 IEA Bos taurus 456216 R-BTA-5672969 https://reactome.org/PathwayBrowser/#/R-BTA-5672969 Phosphorylation of RAF IEA Bos taurus 456216 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 456216 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 456216 R-BTA-5673768 https://reactome.org/PathwayBrowser/#/R-BTA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Bos taurus 456216 R-BTA-5674130 https://reactome.org/PathwayBrowser/#/R-BTA-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Bos taurus 456216 R-BTA-5674373 https://reactome.org/PathwayBrowser/#/R-BTA-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Bos taurus 456216 R-BTA-5674496 https://reactome.org/PathwayBrowser/#/R-BTA-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Bos taurus 456216 R-BTA-5675198 https://reactome.org/PathwayBrowser/#/R-BTA-5675198 Activated MAPKs phosphorylate BRAF IEA Bos taurus 456216 R-BTA-5675868 https://reactome.org/PathwayBrowser/#/R-BTA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Bos taurus 456216 R-BTA-5678706 https://reactome.org/PathwayBrowser/#/R-BTA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Bos taurus 456216 R-BTA-5678863 https://reactome.org/PathwayBrowser/#/R-BTA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-5679041 https://reactome.org/PathwayBrowser/#/R-BTA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-5679205 https://reactome.org/PathwayBrowser/#/R-BTA-5679205 ULK1 phosphorylates Beclin-1 IEA Bos taurus 456216 R-BTA-5682026 https://reactome.org/PathwayBrowser/#/R-BTA-5682026 MRN bound to shortened telomeres activates ATM IEA Bos taurus 456216 R-BTA-5682101 https://reactome.org/PathwayBrowser/#/R-BTA-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Bos taurus 456216 R-BTA-5682285 https://reactome.org/PathwayBrowser/#/R-BTA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-5682598 https://reactome.org/PathwayBrowser/#/R-BTA-5682598 ATM phosphorylates HERC2 IEA Bos taurus 456216 R-BTA-5682983 https://reactome.org/PathwayBrowser/#/R-BTA-5682983 ATM phosphorylates WHSC1 IEA Bos taurus 456216 R-BTA-5683425 https://reactome.org/PathwayBrowser/#/R-BTA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Bos taurus 456216 R-BTA-5683714 https://reactome.org/PathwayBrowser/#/R-BTA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Bos taurus 456216 R-BTA-5683792 https://reactome.org/PathwayBrowser/#/R-BTA-5683792 p-T68-CHEK2 autophosphorylates IEA Bos taurus 456216 R-BTA-5683801 https://reactome.org/PathwayBrowser/#/R-BTA-5683801 CHEK2 phosphorylates BRCA1 IEA Bos taurus 456216 R-BTA-5683930 https://reactome.org/PathwayBrowser/#/R-BTA-5683930 WICH phosphorylates H2AFX on Y142 IEA Bos taurus 456216 R-BTA-5683964 https://reactome.org/PathwayBrowser/#/R-BTA-5683964 ATM phosphorylates EYA1-4 IEA Bos taurus 456216 R-BTA-5684096 https://reactome.org/PathwayBrowser/#/R-BTA-5684096 CDK2 phosphorylates RBBP8 IEA Bos taurus 456216 R-BTA-5684140 https://reactome.org/PathwayBrowser/#/R-BTA-5684140 ATM phosphorylates RBBP8 IEA Bos taurus 456216 R-BTA-5684261 https://reactome.org/PathwayBrowser/#/R-BTA-5684261 MAP3K8 is phosphorylated IEA Bos taurus 456216 R-BTA-5684267 https://reactome.org/PathwayBrowser/#/R-BTA-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex IEA Bos taurus 456216 R-BTA-5684275 https://reactome.org/PathwayBrowser/#/R-BTA-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 IEA Bos taurus 456216 R-BTA-5684806 https://reactome.org/PathwayBrowser/#/R-BTA-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN IEA Bos taurus 456216 R-BTA-5685156 https://reactome.org/PathwayBrowser/#/R-BTA-5685156 ATR phosphorylates RPA2 IEA Bos taurus 456216 R-BTA-5686578 https://reactome.org/PathwayBrowser/#/R-BTA-5686578 Activated ATM phosphorylates ABL1 IEA Bos taurus 456216 R-BTA-5686587 https://reactome.org/PathwayBrowser/#/R-BTA-5686587 ABL1 phosphorylates RAD52 IEA Bos taurus 456216 R-BTA-5686704 https://reactome.org/PathwayBrowser/#/R-BTA-5686704 Activated ATM phosphorylates DCLRE1C IEA Bos taurus 456216 R-BTA-5687086 https://reactome.org/PathwayBrowser/#/R-BTA-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Bos taurus 456216 R-BTA-5687088 https://reactome.org/PathwayBrowser/#/R-BTA-5687088 PKA phosphorylates MAPKAPK5 IEA Bos taurus 456216 R-BTA-5687090 https://reactome.org/PathwayBrowser/#/R-BTA-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Bos taurus 456216 R-BTA-5687094 https://reactome.org/PathwayBrowser/#/R-BTA-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Bos taurus 456216 R-BTA-5687101 https://reactome.org/PathwayBrowser/#/R-BTA-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Bos taurus 456216 R-BTA-5687121 https://reactome.org/PathwayBrowser/#/R-BTA-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Bos taurus 456216 R-BTA-5687183 https://reactome.org/PathwayBrowser/#/R-BTA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Bos taurus 456216 R-BTA-5690250 https://reactome.org/PathwayBrowser/#/R-BTA-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Bos taurus 456216 R-BTA-5690702 https://reactome.org/PathwayBrowser/#/R-BTA-5690702 LYN phosphorylates CD22 IEA Bos taurus 456216 R-BTA-5690996 https://reactome.org/PathwayBrowser/#/R-BTA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Bos taurus 456216 R-BTA-5692462 https://reactome.org/PathwayBrowser/#/R-BTA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Bos taurus 456216 R-BTA-5692480 https://reactome.org/PathwayBrowser/#/R-BTA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Bos taurus 456216 R-BTA-5692755 https://reactome.org/PathwayBrowser/#/R-BTA-5692755 CDK1 phosphorylates MAPK6 IEA Bos taurus 456216 R-BTA-5692775 https://reactome.org/PathwayBrowser/#/R-BTA-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Bos taurus 456216 R-BTA-5692779 https://reactome.org/PathwayBrowser/#/R-BTA-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Bos taurus 456216 R-BTA-5693148 https://reactome.org/PathwayBrowser/#/R-BTA-5693148 BCKDK phosphorylates BCKDH IEA Bos taurus 456216 R-BTA-5693536 https://reactome.org/PathwayBrowser/#/R-BTA-5693536 ATM phosphorylates MDC1 IEA Bos taurus 456216 R-BTA-5693540 https://reactome.org/PathwayBrowser/#/R-BTA-5693540 MRN activates ATM IEA Bos taurus 456216 R-BTA-5693549 https://reactome.org/PathwayBrowser/#/R-BTA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Bos taurus 456216 R-BTA-5693551 https://reactome.org/PathwayBrowser/#/R-BTA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Bos taurus 456216 R-BTA-5693575 https://reactome.org/PathwayBrowser/#/R-BTA-5693575 DNA-PKcs autophosphorylates IEA Bos taurus 456216 R-BTA-5693598 https://reactome.org/PathwayBrowser/#/R-BTA-5693598 ATM phosphorylates NBN IEA Bos taurus 456216 R-BTA-5693609 https://reactome.org/PathwayBrowser/#/R-BTA-5693609 ATM phosphorylates TP53 at S15 IEA Bos taurus 456216 R-BTA-5694441 https://reactome.org/PathwayBrowser/#/R-BTA-5694441 CSNK1D phosphorylates SEC23 IEA Bos taurus 456216 R-BTA-5696021 https://reactome.org/PathwayBrowser/#/R-BTA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Bos taurus 456216 R-BTA-5696074 https://reactome.org/PathwayBrowser/#/R-BTA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Bos taurus 456216 R-BTA-5696839 https://reactome.org/PathwayBrowser/#/R-BTA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Bos taurus 456216 R-BTA-6782131 https://reactome.org/PathwayBrowser/#/R-BTA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Bos taurus 456216 R-BTA-6784006 https://reactome.org/PathwayBrowser/#/R-BTA-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Bos taurus 456216 R-BTA-6784319 https://reactome.org/PathwayBrowser/#/R-BTA-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Bos taurus 456216 R-BTA-6784324 https://reactome.org/PathwayBrowser/#/R-BTA-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Bos taurus 456216 R-BTA-6786050 https://reactome.org/PathwayBrowser/#/R-BTA-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Bos taurus 456216 R-BTA-6786095 https://reactome.org/PathwayBrowser/#/R-BTA-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Bos taurus 456216 R-BTA-6786096 https://reactome.org/PathwayBrowser/#/R-BTA-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Bos taurus 456216 R-BTA-6786245 https://reactome.org/PathwayBrowser/#/R-BTA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Bos taurus 456216 R-BTA-6787540 https://reactome.org/PathwayBrowser/#/R-BTA-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Bos taurus 456216 R-BTA-6788392 https://reactome.org/PathwayBrowser/#/R-BTA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Bos taurus 456216 R-BTA-6788582 https://reactome.org/PathwayBrowser/#/R-BTA-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Bos taurus 456216 R-BTA-6788798 https://reactome.org/PathwayBrowser/#/R-BTA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 456216 R-BTA-6788810 https://reactome.org/PathwayBrowser/#/R-BTA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 456216 R-BTA-6788855 https://reactome.org/PathwayBrowser/#/R-BTA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Bos taurus 456216 R-BTA-6793661 https://reactome.org/PathwayBrowser/#/R-BTA-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Bos taurus 456216 R-BTA-6797606 https://reactome.org/PathwayBrowser/#/R-BTA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Bos taurus 456216 R-BTA-6798174 https://reactome.org/PathwayBrowser/#/R-BTA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Bos taurus 456216 R-BTA-6798372 https://reactome.org/PathwayBrowser/#/R-BTA-6798372 ATM phosphorylates DYRK2 IEA Bos taurus 456216 R-BTA-6798374 https://reactome.org/PathwayBrowser/#/R-BTA-6798374 DYRK2 phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6799097 https://reactome.org/PathwayBrowser/#/R-BTA-6799097 ATM phosphorylates ZNF420 IEA Bos taurus 456216 R-BTA-6799332 https://reactome.org/PathwayBrowser/#/R-BTA-6799332 ATR phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6799409 https://reactome.org/PathwayBrowser/#/R-BTA-6799409 HIPK2 phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6799495 https://reactome.org/PathwayBrowser/#/R-BTA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Bos taurus 456216 R-BTA-6800490 https://reactome.org/PathwayBrowser/#/R-BTA-6800490 ATM phosphorylates PIDD1 IEA Bos taurus 456216 R-BTA-6801342 https://reactome.org/PathwayBrowser/#/R-BTA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Bos taurus 456216 R-BTA-6801456 https://reactome.org/PathwayBrowser/#/R-BTA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Bos taurus 456216 R-BTA-6801666 https://reactome.org/PathwayBrowser/#/R-BTA-6801666 PLK2 phosphorylates CENPJ IEA Bos taurus 456216 R-BTA-6801675 https://reactome.org/PathwayBrowser/#/R-BTA-6801675 PLK2 phosphorylates NPM1 IEA Bos taurus 456216 R-BTA-6802973 https://reactome.org/PathwayBrowser/#/R-BTA-6802973 PLK3 phosphorylates CDC25C IEA Bos taurus 456216 R-BTA-6803771 https://reactome.org/PathwayBrowser/#/R-BTA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Bos taurus 456216 R-BTA-6804266 https://reactome.org/PathwayBrowser/#/R-BTA-6804266 CHEK2 phosphorylates TTC5 IEA Bos taurus 456216 R-BTA-6804276 https://reactome.org/PathwayBrowser/#/R-BTA-6804276 ATM phosphorylates TTC5 IEA Bos taurus 456216 R-BTA-6804955 https://reactome.org/PathwayBrowser/#/R-BTA-6804955 ATM phosphorylates MDM2 IEA Bos taurus 456216 R-BTA-6805059 https://reactome.org/PathwayBrowser/#/R-BTA-6805059 CK2:FACT phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6805103 https://reactome.org/PathwayBrowser/#/R-BTA-6805103 AURKA phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6805109 https://reactome.org/PathwayBrowser/#/R-BTA-6805109 CDK2 phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6805126 https://reactome.org/PathwayBrowser/#/R-BTA-6805126 AURKB phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6805276 https://reactome.org/PathwayBrowser/#/R-BTA-6805276 CDK5 phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6805285 https://reactome.org/PathwayBrowser/#/R-BTA-6805285 PLK3 phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6805399 https://reactome.org/PathwayBrowser/#/R-BTA-6805399 TAF1 phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6805470 https://reactome.org/PathwayBrowser/#/R-BTA-6805470 AMPK phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6805479 https://reactome.org/PathwayBrowser/#/R-BTA-6805479 TP53RK phosphorylates TP53 IEA Bos taurus 456216 R-BTA-6805507 https://reactome.org/PathwayBrowser/#/R-BTA-6805507 APAF1 binds AVEN IEA Bos taurus 456216 R-BTA-6806877 https://reactome.org/PathwayBrowser/#/R-BTA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Bos taurus 456216 R-BTA-6806967 https://reactome.org/PathwayBrowser/#/R-BTA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Bos taurus 456216 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 456216 R-BTA-6807868 https://reactome.org/PathwayBrowser/#/R-BTA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Bos taurus 456216 R-BTA-6810233 https://reactome.org/PathwayBrowser/#/R-BTA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Bos taurus 456216 R-BTA-6810472 https://reactome.org/PathwayBrowser/#/R-BTA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Bos taurus 456216 R-BTA-6811454 https://reactome.org/PathwayBrowser/#/R-BTA-6811454 MAPKs phosphorylate PP2A IEA Bos taurus 456216 R-BTA-6811522 https://reactome.org/PathwayBrowser/#/R-BTA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Bos taurus 456216 R-BTA-6814119 https://reactome.org/PathwayBrowser/#/R-BTA-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Bos taurus 456216 R-BTA-6814120 https://reactome.org/PathwayBrowser/#/R-BTA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Bos taurus 456216 R-BTA-6814121 https://reactome.org/PathwayBrowser/#/R-BTA-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Bos taurus 456216 R-BTA-6814124 https://reactome.org/PathwayBrowser/#/R-BTA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Bos taurus 456216 R-BTA-6814409 https://reactome.org/PathwayBrowser/#/R-BTA-6814409 CK2 phosphorylates PDCL IEA Bos taurus 456216 R-BTA-6814670 https://reactome.org/PathwayBrowser/#/R-BTA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Bos taurus 456216 R-BTA-6814683 https://reactome.org/PathwayBrowser/#/R-BTA-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Bos taurus 456216 R-BTA-68944 https://reactome.org/PathwayBrowser/#/R-BTA-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Bos taurus 456216 R-BTA-68954 https://reactome.org/PathwayBrowser/#/R-BTA-68954 Mcm2-7 is phosphorylated by DDK IEA Bos taurus 456216 R-BTA-69005 https://reactome.org/PathwayBrowser/#/R-BTA-69005 Cdc6 protein is phosphorylated by CDK IEA Bos taurus 456216 R-BTA-69063 https://reactome.org/PathwayBrowser/#/R-BTA-69063 Loading of PCNA - Sliding Clamp Formation IEA Bos taurus 456216 R-BTA-69195 https://reactome.org/PathwayBrowser/#/R-BTA-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Bos taurus 456216 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 456216 R-BTA-69608 https://reactome.org/PathwayBrowser/#/R-BTA-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Bos taurus 456216 R-BTA-69685 https://reactome.org/PathwayBrowser/#/R-BTA-69685 CHEK2 phosphorylates TP53 IEA Bos taurus 456216 R-BTA-69891 https://reactome.org/PathwayBrowser/#/R-BTA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Bos taurus 456216 R-BTA-70333 https://reactome.org/PathwayBrowser/#/R-BTA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Bos taurus 456216 R-BTA-70349 https://reactome.org/PathwayBrowser/#/R-BTA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Bos taurus 456216 R-BTA-70355 https://reactome.org/PathwayBrowser/#/R-BTA-70355 GALK1 phosphorylates Gal to Gal1P IEA Bos taurus 456216 R-BTA-70420 https://reactome.org/PathwayBrowser/#/R-BTA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Bos taurus 456216 R-BTA-70467 https://reactome.org/PathwayBrowser/#/R-BTA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Bos taurus 456216 R-BTA-70486 https://reactome.org/PathwayBrowser/#/R-BTA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Bos taurus 456216 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 456216 R-BTA-70555 https://reactome.org/PathwayBrowser/#/R-BTA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Bos taurus 456216 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Bos taurus 456216 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Bos taurus 456216 R-BTA-70606 https://reactome.org/PathwayBrowser/#/R-BTA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Bos taurus 456216 R-BTA-70773 https://reactome.org/PathwayBrowser/#/R-BTA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Bos taurus 456216 R-BTA-70967 https://reactome.org/PathwayBrowser/#/R-BTA-70967 IDH3 complex decarboxylates isocitrate IEA Bos taurus 456216 R-BTA-70997 https://reactome.org/PathwayBrowser/#/R-BTA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Bos taurus 456216 R-BTA-71031 https://reactome.org/PathwayBrowser/#/R-BTA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Bos taurus 456216 R-BTA-71401 https://reactome.org/PathwayBrowser/#/R-BTA-71401 OGDH dimer decarboxylates 2-OG IEA Bos taurus 456216 R-BTA-71541 https://reactome.org/PathwayBrowser/#/R-BTA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Bos taurus 456216 R-BTA-71588 https://reactome.org/PathwayBrowser/#/R-BTA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Bos taurus 456216 R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 456216 R-BTA-71802 https://reactome.org/PathwayBrowser/#/R-BTA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Bos taurus 456216 R-BTA-71850 https://reactome.org/PathwayBrowser/#/R-BTA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Bos taurus 456216 R-BTA-72621 https://reactome.org/PathwayBrowser/#/R-BTA-72621 Ribosomal scanning IEA Bos taurus 456216 R-BTA-727819 https://reactome.org/PathwayBrowser/#/R-BTA-727819 TAK1 phosphorylates MKK6 IEA Bos taurus 456216 R-BTA-73548 https://reactome.org/PathwayBrowser/#/R-BTA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Bos taurus 456216 R-BTA-73577 https://reactome.org/PathwayBrowser/#/R-BTA-73577 CAD hexamer transforms L-Gln to CAP IEA Bos taurus 456216 R-BTA-73598 https://reactome.org/PathwayBrowser/#/R-BTA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Bos taurus 456216 R-BTA-73599 https://reactome.org/PathwayBrowser/#/R-BTA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Bos taurus 456216 R-BTA-73632 https://reactome.org/PathwayBrowser/#/R-BTA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Bos taurus 456216 R-BTA-73635 https://reactome.org/PathwayBrowser/#/R-BTA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Bos taurus 456216 R-BTA-73647 https://reactome.org/PathwayBrowser/#/R-BTA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Bos taurus 456216 R-BTA-73722 https://reactome.org/PathwayBrowser/#/R-BTA-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Bos taurus 456216 R-BTA-73788 https://reactome.org/PathwayBrowser/#/R-BTA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Bos taurus 456216 R-BTA-73805 https://reactome.org/PathwayBrowser/#/R-BTA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Bos taurus 456216 R-BTA-73810 https://reactome.org/PathwayBrowser/#/R-BTA-73810 FGAM + ATP => AIR + ADP + Pi IEA Bos taurus 456216 R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 456216 R-BTA-73814 https://reactome.org/PathwayBrowser/#/R-BTA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Bos taurus 456216 R-BTA-74207 https://reactome.org/PathwayBrowser/#/R-BTA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Bos taurus 456216 R-BTA-74220 https://reactome.org/PathwayBrowser/#/R-BTA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Bos taurus 456216 R-BTA-74618 https://reactome.org/PathwayBrowser/#/R-BTA-74618 PkCa/q phosphorylate Rgs9-1:Gn5b:R9s9bp TAS Bos taurus 456216 R-BTA-74711 https://reactome.org/PathwayBrowser/#/R-BTA-74711 Phosphorylation of IRS IEA Bos taurus 456216 R-BTA-74715 https://reactome.org/PathwayBrowser/#/R-BTA-74715 Autophosphorylation of insulin receptor IEA Bos taurus 456216 R-BTA-74742 https://reactome.org/PathwayBrowser/#/R-BTA-74742 Phosphorylation of SHC1 IEA Bos taurus 456216 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 456216 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 456216 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 456216 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 456216 R-BTA-75125 https://reactome.org/PathwayBrowser/#/R-BTA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Bos taurus 456216 R-BTA-75126 https://reactome.org/PathwayBrowser/#/R-BTA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Bos taurus 456216 R-BTA-75809 https://reactome.org/PathwayBrowser/#/R-BTA-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Bos taurus 456216 R-BTA-75848 https://reactome.org/PathwayBrowser/#/R-BTA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Bos taurus 456216 R-BTA-75851 https://reactome.org/PathwayBrowser/#/R-BTA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 456216 R-BTA-75887 https://reactome.org/PathwayBrowser/#/R-BTA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Bos taurus 456216 R-BTA-75949 https://reactome.org/PathwayBrowser/#/R-BTA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Bos taurus 456216 R-BTA-77071 https://reactome.org/PathwayBrowser/#/R-BTA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Bos taurus 456216 R-BTA-873918 https://reactome.org/PathwayBrowser/#/R-BTA-873918 Transphosphorylation of JAK1 IEA Bos taurus 456216 R-BTA-873919 https://reactome.org/PathwayBrowser/#/R-BTA-873919 Phosphorylation of JAK2 IEA Bos taurus 456216 R-BTA-873922 https://reactome.org/PathwayBrowser/#/R-BTA-873922 Phosphorylation of STAT1 by JAK kinases IEA Bos taurus 456216 R-BTA-873924 https://reactome.org/PathwayBrowser/#/R-BTA-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Bos taurus 456216 R-BTA-879907 https://reactome.org/PathwayBrowser/#/R-BTA-879907 Tyrosine kinases phosphorylate the receptor IEA Bos taurus 456216 R-BTA-879909 https://reactome.org/PathwayBrowser/#/R-BTA-879909 Activation of STAT5a/b by JAK2 IEA Bos taurus 456216 R-BTA-879910 https://reactome.org/PathwayBrowser/#/R-BTA-879910 JAK2 is phosphorylated, activated IEA Bos taurus 456216 R-BTA-8847638 https://reactome.org/PathwayBrowser/#/R-BTA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Bos taurus 456216 R-BTA-8847977 https://reactome.org/PathwayBrowser/#/R-BTA-8847977 FRK phosphorylates PTEN IEA Bos taurus 456216 R-BTA-8848005 https://reactome.org/PathwayBrowser/#/R-BTA-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Bos taurus 456216 R-BTA-8848053 https://reactome.org/PathwayBrowser/#/R-BTA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Bos taurus 456216 R-BTA-8848077 https://reactome.org/PathwayBrowser/#/R-BTA-8848077 PTK6 phosphorylates STAP2 IEA Bos taurus 456216 R-BTA-8848124 https://reactome.org/PathwayBrowser/#/R-BTA-8848124 PTK6 phosphorylates STAT3 IEA Bos taurus 456216 R-BTA-8848436 https://reactome.org/PathwayBrowser/#/R-BTA-8848436 PTK6 phosphorylates CDKN1B IEA Bos taurus 456216 R-BTA-8848606 https://reactome.org/PathwayBrowser/#/R-BTA-8848606 PTK6 phosphorylates PXN IEA Bos taurus 456216 R-BTA-8848726 https://reactome.org/PathwayBrowser/#/R-BTA-8848726 PTK6 phosphorylates BCAR1 IEA Bos taurus 456216 R-BTA-8848776 https://reactome.org/PathwayBrowser/#/R-BTA-8848776 PTK6 phosphorylates DOK1 IEA Bos taurus 456216 R-BTA-8848818 https://reactome.org/PathwayBrowser/#/R-BTA-8848818 PTK6 phosphorylates CBL IEA Bos taurus 456216 R-BTA-8848873 https://reactome.org/PathwayBrowser/#/R-BTA-8848873 PTK6 phosphorylates ARAP1 IEA Bos taurus 456216 R-BTA-8848975 https://reactome.org/PathwayBrowser/#/R-BTA-8848975 PTK6 phosphorylates KHDRBS1 IEA Bos taurus 456216 R-BTA-8849032 https://reactome.org/PathwayBrowser/#/R-BTA-8849032 PTK6 phosphorylates KHDRBS2 IEA Bos taurus 456216 R-BTA-8849042 https://reactome.org/PathwayBrowser/#/R-BTA-8849042 PTK6 phosphorylates KHDRBS3 IEA Bos taurus 456216 R-BTA-8849068 https://reactome.org/PathwayBrowser/#/R-BTA-8849068 PTK6 phosphorylates ARHGAP35 IEA Bos taurus 456216 R-BTA-8849102 https://reactome.org/PathwayBrowser/#/R-BTA-8849102 SRMS phosphorylates PTK6 IEA Bos taurus 456216 R-BTA-8849353 https://reactome.org/PathwayBrowser/#/R-BTA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Bos taurus 456216 R-BTA-8849463 https://reactome.org/PathwayBrowser/#/R-BTA-8849463 PTK6 phosphorylates SFPQ IEA Bos taurus 456216 R-BTA-8850527 https://reactome.org/PathwayBrowser/#/R-BTA-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Bos taurus 456216 R-BTA-8850529 https://reactome.org/PathwayBrowser/#/R-BTA-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Bos taurus 456216 R-BTA-8850534 https://reactome.org/PathwayBrowser/#/R-BTA-8850534 PDCL promotes G-protein beta 5 folding IEA Bos taurus 456216 R-BTA-8850539 https://reactome.org/PathwayBrowser/#/R-BTA-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Bos taurus 456216 R-BTA-8850945 https://reactome.org/PathwayBrowser/#/R-BTA-8850945 Casein kinase II phosphorylates PTEN IEA Bos taurus 456216 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 456216 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 456216 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 456216 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 456216 R-BTA-8851797 https://reactome.org/PathwayBrowser/#/R-BTA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Bos taurus 456216 R-BTA-8851890 https://reactome.org/PathwayBrowser/#/R-BTA-8851890 MET phosphorylates SHC1-2 IEA Bos taurus 456216 R-BTA-8851933 https://reactome.org/PathwayBrowser/#/R-BTA-8851933 MET phosphorylates GAB1 IEA Bos taurus 456216 R-BTA-8852019 https://reactome.org/PathwayBrowser/#/R-BTA-8852019 MET bound PI3K generates PIP3 IEA Bos taurus 456216 R-BTA-8852306 https://reactome.org/PathwayBrowser/#/R-BTA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Bos taurus 456216 R-BTA-8852317 https://reactome.org/PathwayBrowser/#/R-BTA-8852317 PLK1 phosphorylates GTSE1 IEA Bos taurus 456216 R-BTA-8852552 https://reactome.org/PathwayBrowser/#/R-BTA-8852552 MST1R autophosphorylates IEA Bos taurus 456216 R-BTA-8853419 https://reactome.org/PathwayBrowser/#/R-BTA-8853419 TPX2 promotes AURKA autophosphorylation IEA Bos taurus 456216 R-BTA-8853444 https://reactome.org/PathwayBrowser/#/R-BTA-8853444 AURKA phosphorylates PHLDA1 IEA Bos taurus 456216 R-BTA-8853774 https://reactome.org/PathwayBrowser/#/R-BTA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Bos taurus 456216 R-BTA-8853792 https://reactome.org/PathwayBrowser/#/R-BTA-8853792 RET tyrosine phosphorylation IEA Bos taurus 456216 R-BTA-8854908 https://reactome.org/PathwayBrowser/#/R-BTA-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Bos taurus 456216 R-BTA-8855237 https://reactome.org/PathwayBrowser/#/R-BTA-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Bos taurus 456216 R-BTA-8856813 https://reactome.org/PathwayBrowser/#/R-BTA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Bos taurus 456216 R-BTA-8857555 https://reactome.org/PathwayBrowser/#/R-BTA-8857555 EGFR phosphorylates GPNMB IEA Bos taurus 456216 R-BTA-8857577 https://reactome.org/PathwayBrowser/#/R-BTA-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Bos taurus 456216 R-BTA-8857583 https://reactome.org/PathwayBrowser/#/R-BTA-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Bos taurus 456216 R-BTA-8857925 https://reactome.org/PathwayBrowser/#/R-BTA-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Bos taurus 456216 R-BTA-8865774 https://reactome.org/PathwayBrowser/#/R-BTA-8865774 TTLLs polyglutamylate tubulin IEA Bos taurus 456216 R-BTA-8866268 https://reactome.org/PathwayBrowser/#/R-BTA-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Bos taurus 456216 R-BTA-8866542 https://reactome.org/PathwayBrowser/#/R-BTA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Bos taurus 456216 R-BTA-8867041 https://reactome.org/PathwayBrowser/#/R-BTA-8867041 EGFR phosphorylates EPS15 IEA Bos taurus 456216 R-BTA-8867370 https://reactome.org/PathwayBrowser/#/R-BTA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Bos taurus 456216 R-BTA-8868066 https://reactome.org/PathwayBrowser/#/R-BTA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Bos taurus 456216 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 456216 R-BTA-8868118 https://reactome.org/PathwayBrowser/#/R-BTA-8868118 MAPK12 phosphorylates PTPN3 IEA Bos taurus 456216 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 456216 R-BTA-8869606 https://reactome.org/PathwayBrowser/#/R-BTA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Bos taurus 456216 R-BTA-8869607 https://reactome.org/PathwayBrowser/#/R-BTA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Bos taurus 456216 R-BTA-8869627 https://reactome.org/PathwayBrowser/#/R-BTA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Bos taurus 456216 R-BTA-8869633 https://reactome.org/PathwayBrowser/#/R-BTA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Bos taurus 456216 R-BTA-8871373 https://reactome.org/PathwayBrowser/#/R-BTA-8871373 BMX phosphorylates RUFY1 IEA Bos taurus 456216 R-BTA-8873929 https://reactome.org/PathwayBrowser/#/R-BTA-8873929 Casein kinase II phosphorylates STARD10 IEA Bos taurus 456216 R-BTA-8874078 https://reactome.org/PathwayBrowser/#/R-BTA-8874078 PTK2 autophosphorylates IEA Bos taurus 456216 R-BTA-8874080 https://reactome.org/PathwayBrowser/#/R-BTA-8874080 SRC phosphorylates PTK2 IEA Bos taurus 456216 R-BTA-8874082 https://reactome.org/PathwayBrowser/#/R-BTA-8874082 MET phosphorylates PTK2 IEA Bos taurus 456216 R-BTA-8875451 https://reactome.org/PathwayBrowser/#/R-BTA-8875451 MET phosphorylates CBL IEA Bos taurus 456216 R-BTA-8875817 https://reactome.org/PathwayBrowser/#/R-BTA-8875817 MET phosphorylates STAT3 IEA Bos taurus 456216 R-BTA-8876446 https://reactome.org/PathwayBrowser/#/R-BTA-8876446 p-ULK1 phosphorylates DENND3 IEA Bos taurus 456216 R-BTA-8876889 https://reactome.org/PathwayBrowser/#/R-BTA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 456216 R-BTA-8877691 https://reactome.org/PathwayBrowser/#/R-BTA-8877691 MAP2K6 phosphorylates PIP4K2B IEA Bos taurus 456216 R-BTA-8878050 https://reactome.org/PathwayBrowser/#/R-BTA-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Bos taurus 456216 R-BTA-8878054 https://reactome.org/PathwayBrowser/#/R-BTA-8878054 HIPK2 phosphorylates RUNX1 IEA Bos taurus 456216 R-BTA-8931653 https://reactome.org/PathwayBrowser/#/R-BTA-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Bos taurus 456216 R-BTA-8937807 https://reactome.org/PathwayBrowser/#/R-BTA-8937807 SRC phosphorylates RUNX3 IEA Bos taurus 456216 R-BTA-8940100 https://reactome.org/PathwayBrowser/#/R-BTA-8940100 CDK1 phosphorylates VCPIP1 IEA Bos taurus 456216 R-BTA-8942575 https://reactome.org/PathwayBrowser/#/R-BTA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Bos taurus 456216 R-BTA-8942607 https://reactome.org/PathwayBrowser/#/R-BTA-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Bos taurus 456216 R-BTA-8942836 https://reactome.org/PathwayBrowser/#/R-BTA-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Bos taurus 456216 R-BTA-8944454 https://reactome.org/PathwayBrowser/#/R-BTA-8944454 mTORC1 phosphorylates MAF1 IEA Bos taurus 456216 R-BTA-8948039 https://reactome.org/PathwayBrowser/#/R-BTA-8948039 FUNDC1 is phosphorylated by CK2 IEA Bos taurus 456216 R-BTA-8948143 https://reactome.org/PathwayBrowser/#/R-BTA-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Bos taurus 456216 R-BTA-8948146 https://reactome.org/PathwayBrowser/#/R-BTA-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Bos taurus 456216 R-BTA-8950269 https://reactome.org/PathwayBrowser/#/R-BTA-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Bos taurus 456216 R-BTA-8950340 https://reactome.org/PathwayBrowser/#/R-BTA-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Bos taurus 456216 R-BTA-8950405 https://reactome.org/PathwayBrowser/#/R-BTA-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Bos taurus 456216 R-BTA-8950423 https://reactome.org/PathwayBrowser/#/R-BTA-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Bos taurus 456216 R-BTA-8950453 https://reactome.org/PathwayBrowser/#/R-BTA-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Bos taurus 456216 R-BTA-8950485 https://reactome.org/PathwayBrowser/#/R-BTA-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Bos taurus 456216 R-BTA-8950537 https://reactome.org/PathwayBrowser/#/R-BTA-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Bos taurus 456216 R-BTA-8950757 https://reactome.org/PathwayBrowser/#/R-BTA-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Bos taurus 456216 R-BTA-8952289 https://reactome.org/PathwayBrowser/#/R-BTA-8952289 FAM20C phosphorylates FAM20C substrates IEA Bos taurus 456216 R-BTA-8954327 https://reactome.org/PathwayBrowser/#/R-BTA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Bos taurus 456216 R-BTA-8955030 https://reactome.org/PathwayBrowser/#/R-BTA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Bos taurus 456216 R-BTA-8955724 https://reactome.org/PathwayBrowser/#/R-BTA-8955724 TTL ligates L-Tyr to the carboxy terminus of alpha-tubulin TAS Bos taurus 456216 R-BTA-8955844 https://reactome.org/PathwayBrowser/#/R-BTA-8955844 RBKS phosphorylates ribose to R5P IEA Bos taurus 456216 R-BTA-8956659 https://reactome.org/PathwayBrowser/#/R-BTA-8956659 ABL1 phosphorylates YAP1 IEA Bos taurus 456216 R-BTA-8959719 https://reactome.org/PathwayBrowser/#/R-BTA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Bos taurus 456216 R-BTA-8964242 https://reactome.org/PathwayBrowser/#/R-BTA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Bos taurus 456216 R-BTA-8982163 https://reactome.org/PathwayBrowser/#/R-BTA-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Bos taurus 456216 R-BTA-8983059 https://reactome.org/PathwayBrowser/#/R-BTA-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Bos taurus 456216 R-BTA-8983063 https://reactome.org/PathwayBrowser/#/R-BTA-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Bos taurus 456216 R-BTA-8983300 https://reactome.org/PathwayBrowser/#/R-BTA-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Bos taurus 456216 R-BTA-8983371 https://reactome.org/PathwayBrowser/#/R-BTA-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Bos taurus 456216 R-BTA-8983834 https://reactome.org/PathwayBrowser/#/R-BTA-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Bos taurus 456216 R-BTA-8983835 https://reactome.org/PathwayBrowser/#/R-BTA-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Bos taurus 456216 R-BTA-8983870 https://reactome.org/PathwayBrowser/#/R-BTA-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Bos taurus 456216 R-BTA-8983872 https://reactome.org/PathwayBrowser/#/R-BTA-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Bos taurus 456216 R-BTA-8984012 https://reactome.org/PathwayBrowser/#/R-BTA-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Bos taurus 456216 R-BTA-8984014 https://reactome.org/PathwayBrowser/#/R-BTA-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Bos taurus 456216 R-BTA-8985914 https://reactome.org/PathwayBrowser/#/R-BTA-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Bos taurus 456216 R-BTA-8985973 https://reactome.org/PathwayBrowser/#/R-BTA-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Bos taurus 456216 R-BTA-8985988 https://reactome.org/PathwayBrowser/#/R-BTA-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Bos taurus 456216 R-BTA-8986985 https://reactome.org/PathwayBrowser/#/R-BTA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Bos taurus 456216 R-BTA-8986994 https://reactome.org/PathwayBrowser/#/R-BTA-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Bos taurus 456216 R-BTA-8986995 https://reactome.org/PathwayBrowser/#/R-BTA-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Bos taurus 456216 R-BTA-8987012 https://reactome.org/PathwayBrowser/#/R-BTA-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Bos taurus 456216 R-BTA-8987040 https://reactome.org/PathwayBrowser/#/R-BTA-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Bos taurus 456216 R-BTA-8987042 https://reactome.org/PathwayBrowser/#/R-BTA-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Bos taurus 456216 R-BTA-8987070 https://reactome.org/PathwayBrowser/#/R-BTA-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Bos taurus 456216 R-BTA-8987084 https://reactome.org/PathwayBrowser/#/R-BTA-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Bos taurus 456216 R-BTA-8987096 https://reactome.org/PathwayBrowser/#/R-BTA-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Bos taurus 456216 R-BTA-8987129 https://reactome.org/PathwayBrowser/#/R-BTA-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Bos taurus 456216 R-BTA-8987141 https://reactome.org/PathwayBrowser/#/R-BTA-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Bos taurus 456216 R-BTA-8987150 https://reactome.org/PathwayBrowser/#/R-BTA-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Bos taurus 456216 R-BTA-8987179 https://reactome.org/PathwayBrowser/#/R-BTA-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Bos taurus 456216 R-BTA-8987202 https://reactome.org/PathwayBrowser/#/R-BTA-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Bos taurus 456216 R-BTA-8987255 https://reactome.org/PathwayBrowser/#/R-BTA-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Bos taurus 456216 R-BTA-9006850 https://reactome.org/PathwayBrowser/#/R-BTA-9006850 IL21 receptor JAK phosphorylation IEA Bos taurus 456216 R-BTA-9006870 https://reactome.org/PathwayBrowser/#/R-BTA-9006870 IL21 receptor STAT phosphorylation IEA Bos taurus 456216 R-BTA-9008043 https://reactome.org/PathwayBrowser/#/R-BTA-9008043 MAPK8 phosphorylation IEA Bos taurus 456216 R-BTA-9008412 https://reactome.org/PathwayBrowser/#/R-BTA-9008412 CDK4 phosphorylates RUNX2 IEA Bos taurus 456216 R-BTA-9008684 https://reactome.org/PathwayBrowser/#/R-BTA-9008684 TBK1 phosphorylation IEA Bos taurus 456216 R-BTA-9009072 https://reactome.org/PathwayBrowser/#/R-BTA-9009072 STAT3 phosphorylation IEA Bos taurus 456216 R-BTA-9009282 https://reactome.org/PathwayBrowser/#/R-BTA-9009282 CDK1 phosphorylates RUNX2 IEA Bos taurus 456216 R-BTA-9012319 https://reactome.org/PathwayBrowser/#/R-BTA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Bos taurus 456216 R-BTA-9021357 https://reactome.org/PathwayBrowser/#/R-BTA-9021357 PRKCI phosphorylates ELF3 IEA Bos taurus 456216 R-BTA-9021609 https://reactome.org/PathwayBrowser/#/R-BTA-9021609 ESR-associated SRC autophosphorylates IEA Bos taurus 456216 R-BTA-9021627 https://reactome.org/PathwayBrowser/#/R-BTA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 456216 R-BTA-9022314 https://reactome.org/PathwayBrowser/#/R-BTA-9022314 HIPK2 phosphorylates MECP2 IEA Bos taurus 456216 R-BTA-9027272 https://reactome.org/PathwayBrowser/#/R-BTA-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Bos taurus 456216 R-BTA-9027273 https://reactome.org/PathwayBrowser/#/R-BTA-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Bos taurus 456216 R-BTA-9033499 https://reactome.org/PathwayBrowser/#/R-BTA-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Bos taurus 456216 R-BTA-9034714 https://reactome.org/PathwayBrowser/#/R-BTA-9034714 NTRK3 dimers trans-autophosphorylate IEA Bos taurus 456216 R-BTA-9038161 https://reactome.org/PathwayBrowser/#/R-BTA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Bos taurus 456216 R-BTA-909552 https://reactome.org/PathwayBrowser/#/R-BTA-909552 Phosphorylation of STAT1 at Ser727 IEA Bos taurus 456216 R-BTA-909718 https://reactome.org/PathwayBrowser/#/R-BTA-909718 Formation of p-STAT1 homodimer IEA Bos taurus 456216 R-BTA-909729 https://reactome.org/PathwayBrowser/#/R-BTA-909729 Activation of JAK kinases IEA Bos taurus 456216 R-BTA-909730 https://reactome.org/PathwayBrowser/#/R-BTA-909730 Phosphorylation of INFAR1 by TYK2 IEA Bos taurus 456216 R-BTA-909732 https://reactome.org/PathwayBrowser/#/R-BTA-909732 Phosphorylation of STAT2 IEA Bos taurus 456216 R-BTA-912527 https://reactome.org/PathwayBrowser/#/R-BTA-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Bos taurus 456216 R-BTA-913996 https://reactome.org/PathwayBrowser/#/R-BTA-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Bos taurus 456216 R-BTA-917693 https://reactome.org/PathwayBrowser/#/R-BTA-917693 ESCRT Disassembly IEA Bos taurus 456216 R-BTA-917841 https://reactome.org/PathwayBrowser/#/R-BTA-917841 Acidification of Tf:TfR1 containing endosome IEA Bos taurus 456216 R-BTA-917979 https://reactome.org/PathwayBrowser/#/R-BTA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-927889 https://reactome.org/PathwayBrowser/#/R-BTA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Bos taurus 456216 R-BTA-934559 https://reactome.org/PathwayBrowser/#/R-BTA-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Bos taurus 456216 R-BTA-936883 https://reactome.org/PathwayBrowser/#/R-BTA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Bos taurus 456216 R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 456216 R-BTA-936951 https://reactome.org/PathwayBrowser/#/R-BTA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Bos taurus 456216 R-BTA-936991 https://reactome.org/PathwayBrowser/#/R-BTA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Bos taurus 456216 R-BTA-937034 https://reactome.org/PathwayBrowser/#/R-BTA-937034 IRAK1 phosphorylates Pellino IEA Bos taurus 456216 R-BTA-937311 https://reactome.org/PathwayBrowser/#/R-BTA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Bos taurus 456216 R-BTA-939763 https://reactome.org/PathwayBrowser/#/R-BTA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Bos taurus 456216 R-BTA-947591 https://reactome.org/PathwayBrowser/#/R-BTA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Bos taurus 456216 R-BTA-9603420 https://reactome.org/PathwayBrowser/#/R-BTA-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Bos taurus 456216 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 456216 R-BTA-9606884 https://reactome.org/PathwayBrowser/#/R-BTA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Bos taurus 456216 R-BTA-9610153 https://reactome.org/PathwayBrowser/#/R-BTA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Bos taurus 456216 R-BTA-9610156 https://reactome.org/PathwayBrowser/#/R-BTA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Bos taurus 456216 R-BTA-9610163 https://reactome.org/PathwayBrowser/#/R-BTA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Bos taurus 456216 R-BTA-9619355 https://reactome.org/PathwayBrowser/#/R-BTA-9619355 CaMKK autophosphorylates in the cytosol IEA Bos taurus 456216 R-BTA-9624800 https://reactome.org/PathwayBrowser/#/R-BTA-9624800 CDK1 phosphorylates LBR IEA Bos taurus 456216 R-BTA-9625487 https://reactome.org/PathwayBrowser/#/R-BTA-9625487 PTK2 autophosphorylates downstream of EGFR IEA Bos taurus 456216 R-BTA-9626817 https://reactome.org/PathwayBrowser/#/R-BTA-9626817 PKC phosphorylates NCF1 IEA Bos taurus 456216 R-BTA-9626832 https://reactome.org/PathwayBrowser/#/R-BTA-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Bos taurus 456216 R-BTA-9626880 https://reactome.org/PathwayBrowser/#/R-BTA-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Bos taurus 456216 R-BTA-9627089 https://reactome.org/PathwayBrowser/#/R-BTA-9627089 CASP9 is phosphorylated at T412 IEA Bos taurus 456216 R-BTA-9632858 https://reactome.org/PathwayBrowser/#/R-BTA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Bos taurus 456216 R-BTA-9632868 https://reactome.org/PathwayBrowser/#/R-BTA-9632868 CDKN1B is phosphorylated in response to estrogen IEA Bos taurus 456216 R-BTA-9634702 https://reactome.org/PathwayBrowser/#/R-BTA-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Bos taurus 456216 R-BTA-9645442 https://reactome.org/PathwayBrowser/#/R-BTA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Bos taurus 456216 R-BTA-9645535 https://reactome.org/PathwayBrowser/#/R-BTA-9645535 ALPK1 phosphorylates TIFA IEA Bos taurus 456216 R-BTA-9648089 https://reactome.org/PathwayBrowser/#/R-BTA-9648089 NEK6 and NEK7 phosphorylate EML4 IEA Bos taurus 456216 R-BTA-964958 https://reactome.org/PathwayBrowser/#/R-BTA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Bos taurus 456216 R-BTA-964962 https://reactome.org/PathwayBrowser/#/R-BTA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Bos taurus 456216 R-BTA-964970 https://reactome.org/PathwayBrowser/#/R-BTA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Bos taurus 456216 R-BTA-9650858 https://reactome.org/PathwayBrowser/#/R-BTA-9650858 Meglitinides bind ABCC8 IEA Bos taurus 456216 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 456216 R-BTA-9653503 https://reactome.org/PathwayBrowser/#/R-BTA-9653503 KRAS4B is phosphorylated on serine 181 IEA Bos taurus 456216 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 456216 R-BTA-9661417 https://reactome.org/PathwayBrowser/#/R-BTA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-9668419 https://reactome.org/PathwayBrowser/#/R-BTA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Bos taurus 456216 R-BTA-9684118 https://reactome.org/PathwayBrowser/#/R-BTA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Bos taurus 456216 R-BTA-9686521 https://reactome.org/PathwayBrowser/#/R-BTA-9686521 CDK2:CCNA phosphorylates TERF2 IEA Bos taurus 456216 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 456216 R-BTA-9699578 https://reactome.org/PathwayBrowser/#/R-BTA-9699578 Active FLT3 phosphorylates CDKN1B IEA Bos taurus 456216 R-BTA-9700168 https://reactome.org/PathwayBrowser/#/R-BTA-9700168 Active ALK phosphorylates IRS1 IEA Bos taurus 456216 R-BTA-9700171 https://reactome.org/PathwayBrowser/#/R-BTA-9700171 Active ALK phosphorylates PLCG1 IEA Bos taurus 456216 R-BTA-9700175 https://reactome.org/PathwayBrowser/#/R-BTA-9700175 Active ALK phosphorylates SHC1 IEA Bos taurus 456216 R-BTA-9701488 https://reactome.org/PathwayBrowser/#/R-BTA-9701488 Active ALK phosphorylates JAK3 IEA Bos taurus 456216 R-BTA-9706344 https://reactome.org/PathwayBrowser/#/R-BTA-9706344 FLT3 phosphorylates GRB10 IEA Bos taurus 456216 R-BTA-9706350 https://reactome.org/PathwayBrowser/#/R-BTA-9706350 FLT3 phosphorylates CBL IEA Bos taurus 456216 R-BTA-9706399 https://reactome.org/PathwayBrowser/#/R-BTA-9706399 RHOBTB3 hydrolyzes ATP IEA Bos taurus 456216 R-BTA-9727198 https://reactome.org/PathwayBrowser/#/R-BTA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Bos taurus 456216 R-BTA-9731111 https://reactome.org/PathwayBrowser/#/R-BTA-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Bos taurus 456216 R-BTA-9732738 https://reactome.org/PathwayBrowser/#/R-BTA-9732738 JAK1-mediated phosphorylation of RAF1 IEA Bos taurus 456216 R-BTA-9732753 https://reactome.org/PathwayBrowser/#/R-BTA-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Bos taurus 456216 R-BTA-9734547 https://reactome.org/PathwayBrowser/#/R-BTA-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Bos taurus 456216 R-BTA-9734687 https://reactome.org/PathwayBrowser/#/R-BTA-9734687 ORC6 is phosphorylated on T195 IEA Bos taurus 456216 R-BTA-9748949 https://reactome.org/PathwayBrowser/#/R-BTA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Bos taurus 456216 R-BTA-9748963 https://reactome.org/PathwayBrowser/#/R-BTA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Bos taurus 456216 R-BTA-9748969 https://reactome.org/PathwayBrowser/#/R-BTA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Bos taurus 456216 R-BTA-9748999 https://reactome.org/PathwayBrowser/#/R-BTA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Bos taurus 456216 R-BTA-9750546 https://reactome.org/PathwayBrowser/#/R-BTA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-9750617 https://reactome.org/PathwayBrowser/#/R-BTA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-9750656 https://reactome.org/PathwayBrowser/#/R-BTA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Bos taurus 456216 R-BTA-975103 https://reactome.org/PathwayBrowser/#/R-BTA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Bos taurus 456216 R-BTA-975139 https://reactome.org/PathwayBrowser/#/R-BTA-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Bos taurus 456216 R-BTA-9753278 https://reactome.org/PathwayBrowser/#/R-BTA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 456216 R-BTA-9753283 https://reactome.org/PathwayBrowser/#/R-BTA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 456216 R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 456216 R-BTA-9754974 https://reactome.org/PathwayBrowser/#/R-BTA-9754974 ADK phosphorylates RBV IEA Bos taurus 456216 R-BTA-9755013 https://reactome.org/PathwayBrowser/#/R-BTA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Bos taurus 456216 R-BTA-9759206 https://reactome.org/PathwayBrowser/#/R-BTA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Bos taurus 456216 R-BTA-9759454 https://reactome.org/PathwayBrowser/#/R-BTA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Bos taurus 456216 R-BTA-9759461 https://reactome.org/PathwayBrowser/#/R-BTA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Bos taurus 456216 R-BTA-9760094 https://reactome.org/PathwayBrowser/#/R-BTA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Bos taurus 456216 R-BTA-9762094 https://reactome.org/PathwayBrowser/#/R-BTA-9762094 GSK3B phosphorylates p-NFE2L2 IEA Bos taurus 456216 R-BTA-9770141 https://reactome.org/PathwayBrowser/#/R-BTA-9770141 Formation of the Spliceosomal C* complex IEA Bos taurus 456216 R-BTA-9770145 https://reactome.org/PathwayBrowser/#/R-BTA-9770145 Formation of the Spliceosomal Bact complex IEA Bos taurus 456216 R-BTA-9773803 https://reactome.org/PathwayBrowser/#/R-BTA-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Bos taurus 456216 R-BTA-9794120 https://reactome.org/PathwayBrowser/#/R-BTA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Bos taurus 456216 R-BTA-9794572 https://reactome.org/PathwayBrowser/#/R-BTA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Bos taurus 456216 R-BTA-9796053 https://reactome.org/PathwayBrowser/#/R-BTA-9796053 PRKCI phosphorylates NFE2L2 IEA Bos taurus 456216 R-BTA-9796067 https://reactome.org/PathwayBrowser/#/R-BTA-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Bos taurus 456216 R-BTA-9815501 https://reactome.org/PathwayBrowser/#/R-BTA-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 IEA Bos taurus 456216 R-BTA-9817397 https://reactome.org/PathwayBrowser/#/R-BTA-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Bos taurus 456216 R-BTA-9818789 https://reactome.org/PathwayBrowser/#/R-BTA-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Bos taurus 456216 R-BTA-9819106 https://reactome.org/PathwayBrowser/#/R-BTA-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Bos taurus 456216 R-BTA-9823906 https://reactome.org/PathwayBrowser/#/R-BTA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Bos taurus 456216 R-BTA-9824882 https://reactome.org/PathwayBrowser/#/R-BTA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Bos taurus 456216 R-BTA-9824977 https://reactome.org/PathwayBrowser/#/R-BTA-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Bos taurus 456216 R-BTA-9824994 https://reactome.org/PathwayBrowser/#/R-BTA-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Bos taurus 456216 R-BTA-9824995 https://reactome.org/PathwayBrowser/#/R-BTA-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Bos taurus 456216 R-BTA-9824999 https://reactome.org/PathwayBrowser/#/R-BTA-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Bos taurus 456216 R-BTA-9825759 https://reactome.org/PathwayBrowser/#/R-BTA-9825759 MAPK-dependent phosphorylation of KARS IEA Bos taurus 456216 R-BTA-983144 https://reactome.org/PathwayBrowser/#/R-BTA-983144 Transport of Antigen peptide in to ER IEA Bos taurus 456216 R-BTA-983259 https://reactome.org/PathwayBrowser/#/R-BTA-983259 Kinesins move along microtubules consuming ATP IEA Bos taurus 456216 R-BTA-9836159 https://reactome.org/PathwayBrowser/#/R-BTA-9836159 p-PKR dimer phosphorylates DHX9 IEA Bos taurus 456216 R-BTA-9836184 https://reactome.org/PathwayBrowser/#/R-BTA-9836184 p-PKR dimer phosphorylates CDK1 IEA Bos taurus 456216 R-BTA-9836322 https://reactome.org/PathwayBrowser/#/R-BTA-9836322 p-PKR dimer phosphorylates MKK6 IEA Bos taurus 456216 R-BTA-9836362 https://reactome.org/PathwayBrowser/#/R-BTA-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Bos taurus 456216 R-BTA-9836383 https://reactome.org/PathwayBrowser/#/R-BTA-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Bos taurus 456216 R-BTA-9836435 https://reactome.org/PathwayBrowser/#/R-BTA-9836435 p-PKR dimer phosphorylates SNCA IEA Bos taurus 456216 R-BTA-9836515 https://reactome.org/PathwayBrowser/#/R-BTA-9836515 p-PKR dimer phosphorylates PTPN2 IEA Bos taurus 456216 R-BTA-9836617 https://reactome.org/PathwayBrowser/#/R-BTA-9836617 p-PKR dimer phosphorylates SPHK1 IEA Bos taurus 456216 R-BTA-9836664 https://reactome.org/PathwayBrowser/#/R-BTA-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Bos taurus 456216 R-BTA-983703 https://reactome.org/PathwayBrowser/#/R-BTA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Bos taurus 456216 R-BTA-983707 https://reactome.org/PathwayBrowser/#/R-BTA-983707 SYK autophosphorylates at the activated BCR IEA Bos taurus 456216 R-BTA-9837333 https://reactome.org/PathwayBrowser/#/R-BTA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Bos taurus 456216 R-BTA-9837337 https://reactome.org/PathwayBrowser/#/R-BTA-9837337 DCAKD phosphorylates DP-CoA IEA Bos taurus 456216 R-BTA-9838004 https://reactome.org/PathwayBrowser/#/R-BTA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Bos taurus 456216 R-BTA-9838081 https://reactome.org/PathwayBrowser/#/R-BTA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Bos taurus 456216 R-BTA-9838289 https://reactome.org/PathwayBrowser/#/R-BTA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Bos taurus 456216 R-BTA-9838321 https://reactome.org/PathwayBrowser/#/R-BTA-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Bos taurus 456216 R-BTA-9839059 https://reactome.org/PathwayBrowser/#/R-BTA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Bos taurus 456216 R-BTA-9839105 https://reactome.org/PathwayBrowser/#/R-BTA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Bos taurus 456216 R-BTA-9839113 https://reactome.org/PathwayBrowser/#/R-BTA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Bos taurus 456216 R-BTA-9843721 https://reactome.org/PathwayBrowser/#/R-BTA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Bos taurus 456216 R-BTA-9851972 https://reactome.org/PathwayBrowser/#/R-BTA-9851972 PLK1 phosphorylates FIRRM at S43 IEA Bos taurus 456216 R-BTA-9853369 https://reactome.org/PathwayBrowser/#/R-BTA-9853369 PLK1 phosphorylates FIRMM at S744 IEA Bos taurus 456216 R-BTA-9861642 https://reactome.org/PathwayBrowser/#/R-BTA-9861642 NEK1 phosphorylates ME1 IEA Bos taurus 456216 R-BTA-994137 https://reactome.org/PathwayBrowser/#/R-BTA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Bos taurus 456216 R-BTA-994140 https://reactome.org/PathwayBrowser/#/R-BTA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Bos taurus 456216 R-CEL-109624 https://reactome.org/PathwayBrowser/#/R-CEL-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Caenorhabditis elegans 456216 R-CEL-109702 https://reactome.org/PathwayBrowser/#/R-CEL-109702 PDPK1 phosphorylates AKT2 IEA Caenorhabditis elegans 456216 R-CEL-109860 https://reactome.org/PathwayBrowser/#/R-CEL-109860 MAP2K1 phosphorylates MAPK3 IEA Caenorhabditis elegans 456216 R-CEL-109862 https://reactome.org/PathwayBrowser/#/R-CEL-109862 MAP2K2 phosphorylates MAPK1 IEA Caenorhabditis elegans 456216 R-CEL-109903 https://reactome.org/PathwayBrowser/#/R-CEL-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Caenorhabditis elegans 456216 R-CEL-110133 https://reactome.org/PathwayBrowser/#/R-CEL-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Caenorhabditis elegans 456216 R-CEL-110137 https://reactome.org/PathwayBrowser/#/R-CEL-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Caenorhabditis elegans 456216 R-CEL-110138 https://reactome.org/PathwayBrowser/#/R-CEL-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 456216 R-CEL-110141 https://reactome.org/PathwayBrowser/#/R-CEL-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Caenorhabditis elegans 456216 R-CEL-110144 https://reactome.org/PathwayBrowser/#/R-CEL-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Caenorhabditis elegans 456216 R-CEL-110145 https://reactome.org/PathwayBrowser/#/R-CEL-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Caenorhabditis elegans 456216 R-CEL-111970 https://reactome.org/PathwayBrowser/#/R-CEL-111970 PKC phosphorylates GRK2 IEA Caenorhabditis elegans 456216 R-CEL-112342 https://reactome.org/PathwayBrowser/#/R-CEL-112342 Inactivation of MAP2K1 by CDK1 IEA Caenorhabditis elegans 456216 R-CEL-114683 https://reactome.org/PathwayBrowser/#/R-CEL-114683 Phosphorylation of Platelet Sec-1 IEA Caenorhabditis elegans 456216 R-CEL-114684 https://reactome.org/PathwayBrowser/#/R-CEL-114684 Phosphorylation of Syntaxin-4 IEA Caenorhabditis elegans 456216 R-CEL-1247935 https://reactome.org/PathwayBrowser/#/R-CEL-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Caenorhabditis elegans 456216 R-CEL-1247960 https://reactome.org/PathwayBrowser/#/R-CEL-1247960 Activation of p38 MAPK IEA Caenorhabditis elegans 456216 R-CEL-1250195 https://reactome.org/PathwayBrowser/#/R-CEL-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Caenorhabditis elegans 456216 R-CEL-1250370 https://reactome.org/PathwayBrowser/#/R-CEL-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Caenorhabditis elegans 456216 R-CEL-1250462 https://reactome.org/PathwayBrowser/#/R-CEL-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Caenorhabditis elegans 456216 R-CEL-1306957 https://reactome.org/PathwayBrowser/#/R-CEL-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Caenorhabditis elegans 456216 R-CEL-1306979 https://reactome.org/PathwayBrowser/#/R-CEL-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Caenorhabditis elegans 456216 R-CEL-1307963 https://reactome.org/PathwayBrowser/#/R-CEL-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Caenorhabditis elegans 456216 R-CEL-1362270 https://reactome.org/PathwayBrowser/#/R-CEL-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Caenorhabditis elegans 456216 R-CEL-1369065 https://reactome.org/PathwayBrowser/#/R-CEL-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Caenorhabditis elegans 456216 R-CEL-1433508 https://reactome.org/PathwayBrowser/#/R-CEL-1433508 PKC alpha interacts with and phosphorylates KIT IEA Caenorhabditis elegans 456216 R-CEL-1433514 https://reactome.org/PathwayBrowser/#/R-CEL-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Caenorhabditis elegans 456216 R-CEL-1454916 https://reactome.org/PathwayBrowser/#/R-CEL-1454916 The ABCC family mediates organic anion transport IEA Caenorhabditis elegans 456216 R-CEL-1467466 https://reactome.org/PathwayBrowser/#/R-CEL-1467466 ABCA4 mediates atRAL transport IEA Caenorhabditis elegans 456216 R-CEL-1483004 https://reactome.org/PathwayBrowser/#/R-CEL-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Caenorhabditis elegans 456216 R-CEL-1483222 https://reactome.org/PathwayBrowser/#/R-CEL-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Caenorhabditis elegans 456216 R-CEL-1524186 https://reactome.org/PathwayBrowser/#/R-CEL-1524186 Phosphorylation of PLCgamma by PDGFR IEA Caenorhabditis elegans 456216 R-CEL-156673 https://reactome.org/PathwayBrowser/#/R-CEL-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Caenorhabditis elegans 456216 R-CEL-156678 https://reactome.org/PathwayBrowser/#/R-CEL-156678 Activation of Cdc25C IEA Caenorhabditis elegans 456216 R-CEL-156682 https://reactome.org/PathwayBrowser/#/R-CEL-156682 PLK1 phosphorylates NUDC IEA Caenorhabditis elegans 456216 R-CEL-159101 https://reactome.org/PathwayBrowser/#/R-CEL-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Caenorhabditis elegans 456216 R-CEL-162657 https://reactome.org/PathwayBrowser/#/R-CEL-162657 Inactivation of Myt1 kinase IEA Caenorhabditis elegans 456216 R-CEL-163215 https://reactome.org/PathwayBrowser/#/R-CEL-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Caenorhabditis elegans 456216 R-CEL-1632857 https://reactome.org/PathwayBrowser/#/R-CEL-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Caenorhabditis elegans 456216 R-CEL-1638845 https://reactome.org/PathwayBrowser/#/R-CEL-1638845 CERK phosphorylates CERA to form C1P IEA Caenorhabditis elegans 456216 R-CEL-164832 https://reactome.org/PathwayBrowser/#/R-CEL-164832 ATPase synthesizes ATP IEA Caenorhabditis elegans 456216 R-CEL-164840 https://reactome.org/PathwayBrowser/#/R-CEL-164840 ADP and Pi bind to ATPase IEA Caenorhabditis elegans 456216 R-CEL-165718 https://reactome.org/PathwayBrowser/#/R-CEL-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Caenorhabditis elegans 456216 R-CEL-165726 https://reactome.org/PathwayBrowser/#/R-CEL-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Caenorhabditis elegans 456216 R-CEL-165758 https://reactome.org/PathwayBrowser/#/R-CEL-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Caenorhabditis elegans 456216 R-CEL-165766 https://reactome.org/PathwayBrowser/#/R-CEL-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Caenorhabditis elegans 456216 R-CEL-1675773 https://reactome.org/PathwayBrowser/#/R-CEL-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Caenorhabditis elegans 456216 R-CEL-1675776 https://reactome.org/PathwayBrowser/#/R-CEL-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Caenorhabditis elegans 456216 R-CEL-1675780 https://reactome.org/PathwayBrowser/#/R-CEL-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Caenorhabditis elegans 456216 R-CEL-1675810 https://reactome.org/PathwayBrowser/#/R-CEL-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Caenorhabditis elegans 456216 R-CEL-1675813 https://reactome.org/PathwayBrowser/#/R-CEL-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Caenorhabditis elegans 456216 R-CEL-1675883 https://reactome.org/PathwayBrowser/#/R-CEL-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Caenorhabditis elegans 456216 R-CEL-1675939 https://reactome.org/PathwayBrowser/#/R-CEL-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Caenorhabditis elegans 456216 R-CEL-1675961 https://reactome.org/PathwayBrowser/#/R-CEL-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Caenorhabditis elegans 456216 R-CEL-1675974 https://reactome.org/PathwayBrowser/#/R-CEL-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Caenorhabditis elegans 456216 R-CEL-1676024 https://reactome.org/PathwayBrowser/#/R-CEL-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Caenorhabditis elegans 456216 R-CEL-1676048 https://reactome.org/PathwayBrowser/#/R-CEL-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Caenorhabditis elegans 456216 R-CEL-1676082 https://reactome.org/PathwayBrowser/#/R-CEL-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Caenorhabditis elegans 456216 R-CEL-1676109 https://reactome.org/PathwayBrowser/#/R-CEL-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Caenorhabditis elegans 456216 R-CEL-1676134 https://reactome.org/PathwayBrowser/#/R-CEL-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Caenorhabditis elegans 456216 R-CEL-1676145 https://reactome.org/PathwayBrowser/#/R-CEL-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Caenorhabditis elegans 456216 R-CEL-1676185 https://reactome.org/PathwayBrowser/#/R-CEL-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Caenorhabditis elegans 456216 R-CEL-168053 https://reactome.org/PathwayBrowser/#/R-CEL-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Caenorhabditis elegans 456216 R-CEL-168136 https://reactome.org/PathwayBrowser/#/R-CEL-168136 Activated JNKs phosphorylate c-JUN IEA Caenorhabditis elegans 456216 R-CEL-168162 https://reactome.org/PathwayBrowser/#/R-CEL-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Caenorhabditis elegans 456216 R-CEL-170026 https://reactome.org/PathwayBrowser/#/R-CEL-170026 Protons are translocated from the intermembrane space to the matrix IEA Caenorhabditis elegans 456216 R-CEL-170055 https://reactome.org/PathwayBrowser/#/R-CEL-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Caenorhabditis elegans 456216 R-CEL-170126 https://reactome.org/PathwayBrowser/#/R-CEL-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Caenorhabditis elegans 456216 R-CEL-170843 https://reactome.org/PathwayBrowser/#/R-CEL-170843 TGFBR2 phosphorylates TGFBR1 IEA Caenorhabditis elegans 456216 R-CEL-170868 https://reactome.org/PathwayBrowser/#/R-CEL-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Caenorhabditis elegans 456216 R-CEL-174367 https://reactome.org/PathwayBrowser/#/R-CEL-174367 GCL ligates L-Glu to L-Cys IEA Caenorhabditis elegans 456216 R-CEL-174389 https://reactome.org/PathwayBrowser/#/R-CEL-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Caenorhabditis elegans 456216 R-CEL-174394 https://reactome.org/PathwayBrowser/#/R-CEL-174394 GSS:Mg2+ dimer synthesizes GSH IEA Caenorhabditis elegans 456216 R-CEL-177284 https://reactome.org/PathwayBrowser/#/R-CEL-177284 PKA phosphorylates PDE4B IEA Caenorhabditis elegans 456216 R-CEL-177930 https://reactome.org/PathwayBrowser/#/R-CEL-177930 GAB1 phosphorylation by EGFR kinase IEA Caenorhabditis elegans 456216 R-CEL-177934 https://reactome.org/PathwayBrowser/#/R-CEL-177934 EGFR autophosphorylation IEA Caenorhabditis elegans 456216 R-CEL-177937 https://reactome.org/PathwayBrowser/#/R-CEL-177937 Phosphorylation of EGFR by SRC kinase IEA Caenorhabditis elegans 456216 R-CEL-177939 https://reactome.org/PathwayBrowser/#/R-CEL-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Caenorhabditis elegans 456216 R-CEL-182969 https://reactome.org/PathwayBrowser/#/R-CEL-182969 Phosphorylation of CBL (EGFR:CBL) IEA Caenorhabditis elegans 456216 R-CEL-183058 https://reactome.org/PathwayBrowser/#/R-CEL-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Caenorhabditis elegans 456216 R-CEL-1855153 https://reactome.org/PathwayBrowser/#/R-CEL-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Caenorhabditis elegans 456216 R-CEL-1855157 https://reactome.org/PathwayBrowser/#/R-CEL-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 456216 R-CEL-1855158 https://reactome.org/PathwayBrowser/#/R-CEL-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 456216 R-CEL-1855181 https://reactome.org/PathwayBrowser/#/R-CEL-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 456216 R-CEL-1855182 https://reactome.org/PathwayBrowser/#/R-CEL-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Caenorhabditis elegans 456216 R-CEL-1855185 https://reactome.org/PathwayBrowser/#/R-CEL-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 456216 R-CEL-1855193 https://reactome.org/PathwayBrowser/#/R-CEL-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 456216 R-CEL-1855194 https://reactome.org/PathwayBrowser/#/R-CEL-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 456216 R-CEL-1855206 https://reactome.org/PathwayBrowser/#/R-CEL-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 456216 R-CEL-1855207 https://reactome.org/PathwayBrowser/#/R-CEL-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 456216 R-CEL-1855216 https://reactome.org/PathwayBrowser/#/R-CEL-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Caenorhabditis elegans 456216 R-CEL-1855223 https://reactome.org/PathwayBrowser/#/R-CEL-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 456216 R-CEL-1855224 https://reactome.org/PathwayBrowser/#/R-CEL-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 456216 R-CEL-1855227 https://reactome.org/PathwayBrowser/#/R-CEL-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 456216 R-CEL-1855228 https://reactome.org/PathwayBrowser/#/R-CEL-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 456216 R-CEL-1855230 https://reactome.org/PathwayBrowser/#/R-CEL-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 456216 R-CEL-1855233 https://reactome.org/PathwayBrowser/#/R-CEL-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Caenorhabditis elegans 456216 R-CEL-186786 https://reactome.org/PathwayBrowser/#/R-CEL-186786 Autophosphorylation of PDGF beta receptors IEA Caenorhabditis elegans 456216 R-CEL-186800 https://reactome.org/PathwayBrowser/#/R-CEL-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Caenorhabditis elegans 456216 R-CEL-187520 https://reactome.org/PathwayBrowser/#/R-CEL-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Caenorhabditis elegans 456216 R-CEL-187688 https://reactome.org/PathwayBrowser/#/R-CEL-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Caenorhabditis elegans 456216 R-CEL-187916 https://reactome.org/PathwayBrowser/#/R-CEL-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Caenorhabditis elegans 456216 R-CEL-190326 https://reactome.org/PathwayBrowser/#/R-CEL-190326 Autocatalytic phosphorylation of FGFR4 IEA Caenorhabditis elegans 456216 R-CEL-190385 https://reactome.org/PathwayBrowser/#/R-CEL-190385 Autocatalytic phosphorylation of FGFR3b IEA Caenorhabditis elegans 456216 R-CEL-190388 https://reactome.org/PathwayBrowser/#/R-CEL-190388 Autocatalytic phosphorylation of FGFR3c IEA Caenorhabditis elegans 456216 R-CEL-190408 https://reactome.org/PathwayBrowser/#/R-CEL-190408 Autocatalytic phosphorylation of FGFR2b IEA Caenorhabditis elegans 456216 R-CEL-190413 https://reactome.org/PathwayBrowser/#/R-CEL-190413 Autocatalytic phosphorylation of FGFR2c IEA Caenorhabditis elegans 456216 R-CEL-190427 https://reactome.org/PathwayBrowser/#/R-CEL-190427 Autocatalytic phosphorylation of FGFR1b IEA Caenorhabditis elegans 456216 R-CEL-190429 https://reactome.org/PathwayBrowser/#/R-CEL-190429 Autocatalytic phosphorylation of FGFR1c IEA Caenorhabditis elegans 456216 R-CEL-191062 https://reactome.org/PathwayBrowser/#/R-CEL-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Caenorhabditis elegans 456216 R-CEL-191380 https://reactome.org/PathwayBrowser/#/R-CEL-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Caenorhabditis elegans 456216 R-CEL-191414 https://reactome.org/PathwayBrowser/#/R-CEL-191414 MVD decarboxylates MVA5PP to IPPP IEA Caenorhabditis elegans 456216 R-CEL-191422 https://reactome.org/PathwayBrowser/#/R-CEL-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Caenorhabditis elegans 456216 R-CEL-194153 https://reactome.org/PathwayBrowser/#/R-CEL-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Caenorhabditis elegans 456216 R-CEL-195275 https://reactome.org/PathwayBrowser/#/R-CEL-195275 Phosphorylation of APC component of the destruction complex IEA Caenorhabditis elegans 456216 R-CEL-195283 https://reactome.org/PathwayBrowser/#/R-CEL-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Caenorhabditis elegans 456216 R-CEL-195287 https://reactome.org/PathwayBrowser/#/R-CEL-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Caenorhabditis elegans 456216 R-CEL-195300 https://reactome.org/PathwayBrowser/#/R-CEL-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Caenorhabditis elegans 456216 R-CEL-195318 https://reactome.org/PathwayBrowser/#/R-CEL-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Caenorhabditis elegans 456216 R-CEL-1963581 https://reactome.org/PathwayBrowser/#/R-CEL-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Caenorhabditis elegans 456216 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 456216 R-CEL-1963586 https://reactome.org/PathwayBrowser/#/R-CEL-1963586 SRC family kinases phosphorylate ERBB2 IEA Caenorhabditis elegans 456216 R-CEL-196773 https://reactome.org/PathwayBrowser/#/R-CEL-196773 COASY phosphorylates DP-CoA IEA Caenorhabditis elegans 456216 R-CEL-196964 https://reactome.org/PathwayBrowser/#/R-CEL-196964 RFK:Mg2+ phosphorylates RIB IEA Caenorhabditis elegans 456216 R-CEL-197958 https://reactome.org/PathwayBrowser/#/R-CEL-197958 FPGS-2 transforms THF to THFPG IEA Caenorhabditis elegans 456216 R-CEL-198314 https://reactome.org/PathwayBrowser/#/R-CEL-198314 DAG stimulates protein kinase C-delta IEA Caenorhabditis elegans 456216 R-CEL-198613 https://reactome.org/PathwayBrowser/#/R-CEL-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Caenorhabditis elegans 456216 R-CEL-198621 https://reactome.org/PathwayBrowser/#/R-CEL-198621 AKT phosphorylates caspase-9 IEA Caenorhabditis elegans 456216 R-CEL-198640 https://reactome.org/PathwayBrowser/#/R-CEL-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Caenorhabditis elegans 456216 R-CEL-198669 https://reactome.org/PathwayBrowser/#/R-CEL-198669 p38MAPK phosphorylates MSK1 IEA Caenorhabditis elegans 456216 R-CEL-198746 https://reactome.org/PathwayBrowser/#/R-CEL-198746 ERK1/2/5 activate RSK1/2/3 IEA Caenorhabditis elegans 456216 R-CEL-198756 https://reactome.org/PathwayBrowser/#/R-CEL-198756 ERK1/2 phosphorylates MSK1 IEA Caenorhabditis elegans 456216 R-CEL-199298 https://reactome.org/PathwayBrowser/#/R-CEL-199298 AKT phosphorylates CREB1 IEA Caenorhabditis elegans 456216 R-CEL-199299 https://reactome.org/PathwayBrowser/#/R-CEL-199299 AKT phosphorylates FOXO transcription factors IEA Caenorhabditis elegans 456216 R-CEL-199839 https://reactome.org/PathwayBrowser/#/R-CEL-199839 AKT can phosphorylate RSK IEA Caenorhabditis elegans 456216 R-CEL-199863 https://reactome.org/PathwayBrowser/#/R-CEL-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Caenorhabditis elegans 456216 R-CEL-199895 https://reactome.org/PathwayBrowser/#/R-CEL-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Caenorhabditis elegans 456216 R-CEL-199910 https://reactome.org/PathwayBrowser/#/R-CEL-199910 MSK1 activates ATF1 IEA Caenorhabditis elegans 456216 R-CEL-199917 https://reactome.org/PathwayBrowser/#/R-CEL-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Caenorhabditis elegans 456216 R-CEL-199935 https://reactome.org/PathwayBrowser/#/R-CEL-199935 MSK1 activates CREB IEA Caenorhabditis elegans 456216 R-CEL-200423 https://reactome.org/PathwayBrowser/#/R-CEL-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Caenorhabditis elegans 456216 R-CEL-200555 https://reactome.org/PathwayBrowser/#/R-CEL-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Caenorhabditis elegans 456216 R-CEL-200681 https://reactome.org/PathwayBrowser/#/R-CEL-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Caenorhabditis elegans 456216 R-CEL-200682 https://reactome.org/PathwayBrowser/#/R-CEL-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Caenorhabditis elegans 456216 R-CEL-200711 https://reactome.org/PathwayBrowser/#/R-CEL-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Caenorhabditis elegans 456216 R-CEL-201443 https://reactome.org/PathwayBrowser/#/R-CEL-201443 Type II receptor phosphorylates type I receptor IEA Caenorhabditis elegans 456216 R-CEL-201476 https://reactome.org/PathwayBrowser/#/R-CEL-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Caenorhabditis elegans 456216 R-CEL-201510 https://reactome.org/PathwayBrowser/#/R-CEL-201510 PI3K synthesizes PIP3 downstream of ALK IEA Caenorhabditis elegans 456216 R-CEL-201677 https://reactome.org/PathwayBrowser/#/R-CEL-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Caenorhabditis elegans 456216 R-CEL-201717 https://reactome.org/PathwayBrowser/#/R-CEL-201717 CSNK2-mediated phosphorylation of DVL IEA Caenorhabditis elegans 456216 R-CEL-202111 https://reactome.org/PathwayBrowser/#/R-CEL-202111 AKT1 phosphorylates eNOS IEA Caenorhabditis elegans 456216 R-CEL-202222 https://reactome.org/PathwayBrowser/#/R-CEL-202222 Phosphorylation of PKC theta IEA Caenorhabditis elegans 456216 R-CEL-2028284 https://reactome.org/PathwayBrowser/#/R-CEL-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Caenorhabditis elegans 456216 R-CEL-2028555 https://reactome.org/PathwayBrowser/#/R-CEL-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Caenorhabditis elegans 456216 R-CEL-2028583 https://reactome.org/PathwayBrowser/#/R-CEL-2028583 Phosphorylation of YAP by LATS2 IEA Caenorhabditis elegans 456216 R-CEL-2028589 https://reactome.org/PathwayBrowser/#/R-CEL-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Caenorhabditis elegans 456216 R-CEL-2028591 https://reactome.org/PathwayBrowser/#/R-CEL-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Caenorhabditis elegans 456216 R-CEL-2028598 https://reactome.org/PathwayBrowser/#/R-CEL-2028598 Phosphorylation of YAP by LATS1 IEA Caenorhabditis elegans 456216 R-CEL-2028629 https://reactome.org/PathwayBrowser/#/R-CEL-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Caenorhabditis elegans 456216 R-CEL-2028635 https://reactome.org/PathwayBrowser/#/R-CEL-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Caenorhabditis elegans 456216 R-CEL-2028661 https://reactome.org/PathwayBrowser/#/R-CEL-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Caenorhabditis elegans 456216 R-CEL-2028670 https://reactome.org/PathwayBrowser/#/R-CEL-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Caenorhabditis elegans 456216 R-CEL-2028673 https://reactome.org/PathwayBrowser/#/R-CEL-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Caenorhabditis elegans 456216 R-CEL-2028675 https://reactome.org/PathwayBrowser/#/R-CEL-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Caenorhabditis elegans 456216 R-CEL-2028679 https://reactome.org/PathwayBrowser/#/R-CEL-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Caenorhabditis elegans 456216 R-CEL-2029454 https://reactome.org/PathwayBrowser/#/R-CEL-2029454 Autophosphorylation of PAK1 IEA Caenorhabditis elegans 456216 R-CEL-2029469 https://reactome.org/PathwayBrowser/#/R-CEL-2029469 p-ERK phosphorylates WAVEs and ABI IEA Caenorhabditis elegans 456216 R-CEL-2029473 https://reactome.org/PathwayBrowser/#/R-CEL-2029473 Branching and elongation of mother and daughter filaments IEA Caenorhabditis elegans 456216 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 456216 R-CEL-2046087 https://reactome.org/PathwayBrowser/#/R-CEL-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Caenorhabditis elegans 456216 R-CEL-2046093 https://reactome.org/PathwayBrowser/#/R-CEL-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Caenorhabditis elegans 456216 R-CEL-205136 https://reactome.org/PathwayBrowser/#/R-CEL-205136 GTP-bound RAC contributes to JNK activation IEA Caenorhabditis elegans 456216 R-CEL-2060328 https://reactome.org/PathwayBrowser/#/R-CEL-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Caenorhabditis elegans 456216 R-CEL-211164 https://reactome.org/PathwayBrowser/#/R-CEL-211164 AKT phosphorylates FOXO1A IEA Caenorhabditis elegans 456216 R-CEL-2130194 https://reactome.org/PathwayBrowser/#/R-CEL-2130194 ABL phosphorylates WAVEs IEA Caenorhabditis elegans 456216 R-CEL-2176475 https://reactome.org/PathwayBrowser/#/R-CEL-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Caenorhabditis elegans 456216 R-CEL-2197690 https://reactome.org/PathwayBrowser/#/R-CEL-2197690 Detachment of WASP/WAVE IEA Caenorhabditis elegans 456216 R-CEL-2197698 https://reactome.org/PathwayBrowser/#/R-CEL-2197698 Src phosphorylate WASP,N-WASP IEA Caenorhabditis elegans 456216 R-CEL-2214351 https://reactome.org/PathwayBrowser/#/R-CEL-2214351 PLK1 phosphorylates GORASP1 IEA Caenorhabditis elegans 456216 R-CEL-2294580 https://reactome.org/PathwayBrowser/#/R-CEL-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Caenorhabditis elegans 456216 R-CEL-2294600 https://reactome.org/PathwayBrowser/#/R-CEL-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Caenorhabditis elegans 456216 R-CEL-2316434 https://reactome.org/PathwayBrowser/#/R-CEL-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 456216 R-CEL-2422927 https://reactome.org/PathwayBrowser/#/R-CEL-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Caenorhabditis elegans 456216 R-CEL-2466068 https://reactome.org/PathwayBrowser/#/R-CEL-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Caenorhabditis elegans 456216 R-CEL-2468293 https://reactome.org/PathwayBrowser/#/R-CEL-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Caenorhabditis elegans 456216 R-CEL-2581474 https://reactome.org/PathwayBrowser/#/R-CEL-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Caenorhabditis elegans 456216 R-CEL-265783 https://reactome.org/PathwayBrowser/#/R-CEL-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Caenorhabditis elegans 456216 R-CEL-2682349 https://reactome.org/PathwayBrowser/#/R-CEL-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Caenorhabditis elegans 456216 R-CEL-2730835 https://reactome.org/PathwayBrowser/#/R-CEL-2730835 Autophosphorylation of PKC-theta IEA Caenorhabditis elegans 456216 R-CEL-2730862 https://reactome.org/PathwayBrowser/#/R-CEL-2730862 Autophosphorylation of LYN kinase IEA Caenorhabditis elegans 456216 R-CEL-2984220 https://reactome.org/PathwayBrowser/#/R-CEL-2984220 CDK1:CCNB phosphorylates NEK9 IEA Caenorhabditis elegans 456216 R-CEL-2984226 https://reactome.org/PathwayBrowser/#/R-CEL-2984226 PLK1 phosphorylates NEK9 IEA Caenorhabditis elegans 456216 R-CEL-2984258 https://reactome.org/PathwayBrowser/#/R-CEL-2984258 NEK9 phosphorylates NEK6/NEK7 IEA Caenorhabditis elegans 456216 R-CEL-3000327 https://reactome.org/PathwayBrowser/#/R-CEL-3000327 PLK1 phosphorylates BORA IEA Caenorhabditis elegans 456216 R-CEL-3095901 https://reactome.org/PathwayBrowser/#/R-CEL-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Caenorhabditis elegans 456216 R-CEL-3228469 https://reactome.org/PathwayBrowser/#/R-CEL-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Caenorhabditis elegans 456216 R-CEL-3249379 https://reactome.org/PathwayBrowser/#/R-CEL-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Caenorhabditis elegans 456216 R-CEL-3371422 https://reactome.org/PathwayBrowser/#/R-CEL-3371422 ATP hydrolysis by HSP70 IEA Caenorhabditis elegans 456216 R-CEL-3371435 https://reactome.org/PathwayBrowser/#/R-CEL-3371435 Constitutive phosphorylation by GSK3 IEA Caenorhabditis elegans 456216 R-CEL-3371503 https://reactome.org/PathwayBrowser/#/R-CEL-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Caenorhabditis elegans 456216 R-CEL-3371531 https://reactome.org/PathwayBrowser/#/R-CEL-3371531 Constitutive phosphorylation by pERK1/2 IEA Caenorhabditis elegans 456216 R-CEL-354073 https://reactome.org/PathwayBrowser/#/R-CEL-354073 Autophosphorylation of PTK2 at Y397 IEA Caenorhabditis elegans 456216 R-CEL-354124 https://reactome.org/PathwayBrowser/#/R-CEL-354124 Phosphorylation of pPTK2 by SRC IEA Caenorhabditis elegans 456216 R-CEL-373747 https://reactome.org/PathwayBrowser/#/R-CEL-373747 Phosphorylation of nephrin by FYN IEA Caenorhabditis elegans 456216 R-CEL-373750 https://reactome.org/PathwayBrowser/#/R-CEL-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Caenorhabditis elegans 456216 R-CEL-374664 https://reactome.org/PathwayBrowser/#/R-CEL-374664 Phosphorylation and activation of Ezrin IEA Caenorhabditis elegans 456216 R-CEL-374701 https://reactome.org/PathwayBrowser/#/R-CEL-374701 Phosphorylation of DCC by Fyn IEA Caenorhabditis elegans 456216 R-CEL-377186 https://reactome.org/PathwayBrowser/#/R-CEL-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Caenorhabditis elegans 456216 R-CEL-3772435 https://reactome.org/PathwayBrowser/#/R-CEL-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Caenorhabditis elegans 456216 R-CEL-3772436 https://reactome.org/PathwayBrowser/#/R-CEL-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Caenorhabditis elegans 456216 R-CEL-377640 https://reactome.org/PathwayBrowser/#/R-CEL-377640 Autophosphorylation of SRC IEA Caenorhabditis elegans 456216 R-CEL-380780 https://reactome.org/PathwayBrowser/#/R-CEL-380780 Activation of Src IEA Caenorhabditis elegans 456216 R-CEL-381091 https://reactome.org/PathwayBrowser/#/R-CEL-381091 IRE1 dimer autophosphorylates IEA Caenorhabditis elegans 456216 R-CEL-381111 https://reactome.org/PathwayBrowser/#/R-CEL-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Caenorhabditis elegans 456216 R-CEL-382560 https://reactome.org/PathwayBrowser/#/R-CEL-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Caenorhabditis elegans 456216 R-CEL-382575 https://reactome.org/PathwayBrowser/#/R-CEL-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Caenorhabditis elegans 456216 R-CEL-383190 https://reactome.org/PathwayBrowser/#/R-CEL-383190 HCO3- transport through ion channel IEA Caenorhabditis elegans 456216 R-CEL-389083 https://reactome.org/PathwayBrowser/#/R-CEL-389083 Autophosphorylation of PDGF alpha receptors IEA Caenorhabditis elegans 456216 R-CEL-389086 https://reactome.org/PathwayBrowser/#/R-CEL-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Caenorhabditis elegans 456216 R-CEL-391266 https://reactome.org/PathwayBrowser/#/R-CEL-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Caenorhabditis elegans 456216 R-CEL-392195 https://reactome.org/PathwayBrowser/#/R-CEL-392195 Gi activation by P2Y purinoceptor 12 IEA Caenorhabditis elegans 456216 R-CEL-392752 https://reactome.org/PathwayBrowser/#/R-CEL-392752 Phosphorylation of L1 by CK-II IEA Caenorhabditis elegans 456216 R-CEL-3928578 https://reactome.org/PathwayBrowser/#/R-CEL-3928578 EPH receptors autophosphorylate IEA Caenorhabditis elegans 456216 R-CEL-3928604 https://reactome.org/PathwayBrowser/#/R-CEL-3928604 SFKs phosphorylate VAV2,3 IEA Caenorhabditis elegans 456216 R-CEL-3928620 https://reactome.org/PathwayBrowser/#/R-CEL-3928620 PAK1 autophosphorylates IEA Caenorhabditis elegans 456216 R-CEL-3928625 https://reactome.org/PathwayBrowser/#/R-CEL-3928625 PAKs autophosphorylate IEA Caenorhabditis elegans 456216 R-CEL-3928627 https://reactome.org/PathwayBrowser/#/R-CEL-3928627 EPHB phosphorylates TIAM1 IEA Caenorhabditis elegans 456216 R-CEL-3928640 https://reactome.org/PathwayBrowser/#/R-CEL-3928640 PAKs phosphorylate MLC IEA Caenorhabditis elegans 456216 R-CEL-399939 https://reactome.org/PathwayBrowser/#/R-CEL-399939 Autophosphorylation of PAK IEA Caenorhabditis elegans 456216 R-CEL-399944 https://reactome.org/PathwayBrowser/#/R-CEL-399944 Phosphorylation of CRMPs by Cdk5 IEA Caenorhabditis elegans 456216 R-CEL-399947 https://reactome.org/PathwayBrowser/#/R-CEL-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Caenorhabditis elegans 456216 R-CEL-399951 https://reactome.org/PathwayBrowser/#/R-CEL-399951 Phosphorylation of CRMPs by GSK3beta IEA Caenorhabditis elegans 456216 R-CEL-4086410 https://reactome.org/PathwayBrowser/#/R-CEL-4086410 CDK1 phosphorylates BORA IEA Caenorhabditis elegans 456216 R-CEL-4093332 https://reactome.org/PathwayBrowser/#/R-CEL-4093332 p-EPHB phosphorylates SDC2 IEA Caenorhabditis elegans 456216 R-CEL-419646 https://reactome.org/PathwayBrowser/#/R-CEL-419646 SEMA4D interacts with Plexin-B1:Met IEA Caenorhabditis elegans 456216 R-CEL-426240 https://reactome.org/PathwayBrowser/#/R-CEL-426240 DAG kinase produces phosphatidic acid from DAG IEA Caenorhabditis elegans 456216 R-CEL-428273 https://reactome.org/PathwayBrowser/#/R-CEL-428273 SPHK1 phosphorylates sphingoid IEA Caenorhabditis elegans 456216 R-CEL-428941 https://reactome.org/PathwayBrowser/#/R-CEL-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Caenorhabditis elegans 456216 R-CEL-429157 https://reactome.org/PathwayBrowser/#/R-CEL-429157 ABCC4 accumulation of dense granule contents IEA Caenorhabditis elegans 456216 R-CEL-429441 https://reactome.org/PathwayBrowser/#/R-CEL-429441 SYK activation by SRC IEA Caenorhabditis elegans 456216 R-CEL-429698 https://reactome.org/PathwayBrowser/#/R-CEL-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Caenorhabditis elegans 456216 R-CEL-429714 https://reactome.org/PathwayBrowser/#/R-CEL-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Caenorhabditis elegans 456216 R-CEL-432148 https://reactome.org/PathwayBrowser/#/R-CEL-432148 Fgr may phosphorylate p38 MAPK IEA Caenorhabditis elegans 456216 R-CEL-4332358 https://reactome.org/PathwayBrowser/#/R-CEL-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Caenorhabditis elegans 456216 R-CEL-4332363 https://reactome.org/PathwayBrowser/#/R-CEL-4332363 Autophosphorylation and activation of CAMK2 IEA Caenorhabditis elegans 456216 R-CEL-437162 https://reactome.org/PathwayBrowser/#/R-CEL-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Caenorhabditis elegans 456216 R-CEL-4411383 https://reactome.org/PathwayBrowser/#/R-CEL-4411383 NLK phosphorylates TCF/LEF IEA Caenorhabditis elegans 456216 R-CEL-4420206 https://reactome.org/PathwayBrowser/#/R-CEL-4420206 Phosphorylation of SRC-1 IEA Caenorhabditis elegans 456216 R-CEL-442724 https://reactome.org/PathwayBrowser/#/R-CEL-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Caenorhabditis elegans 456216 R-CEL-442749 https://reactome.org/PathwayBrowser/#/R-CEL-442749 CaMKK autophosphorylates in the nucleus IEA Caenorhabditis elegans 456216 R-CEL-445072 https://reactome.org/PathwayBrowser/#/R-CEL-445072 Interaction of PAK1 with Rac1-GTP IEA Caenorhabditis elegans 456216 R-CEL-445079 https://reactome.org/PathwayBrowser/#/R-CEL-445079 Phosphorylation of L1 by ERK IEA Caenorhabditis elegans 456216 R-CEL-445084 https://reactome.org/PathwayBrowser/#/R-CEL-445084 Phosphorylation of L1 by SRC IEA Caenorhabditis elegans 456216 R-CEL-445699 https://reactome.org/PathwayBrowser/#/R-CEL-445699 ATP Hydrolysis By Myosin IEA Caenorhabditis elegans 456216 R-CEL-445705 https://reactome.org/PathwayBrowser/#/R-CEL-445705 Release Of ADP From Myosin IEA Caenorhabditis elegans 456216 R-CEL-447074 https://reactome.org/PathwayBrowser/#/R-CEL-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Caenorhabditis elegans 456216 R-CEL-448955 https://reactome.org/PathwayBrowser/#/R-CEL-448955 Phosphorylation of MEF2 proteins by p38 IEA Caenorhabditis elegans 456216 R-CEL-450222 https://reactome.org/PathwayBrowser/#/R-CEL-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Caenorhabditis elegans 456216 R-CEL-450325 https://reactome.org/PathwayBrowser/#/R-CEL-450325 c-FOS activation by phospho ERK1/2 IEA Caenorhabditis elegans 456216 R-CEL-450333 https://reactome.org/PathwayBrowser/#/R-CEL-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Caenorhabditis elegans 456216 R-CEL-450463 https://reactome.org/PathwayBrowser/#/R-CEL-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Caenorhabditis elegans 456216 R-CEL-450474 https://reactome.org/PathwayBrowser/#/R-CEL-450474 MK2 phosphorylates BRF1 IEA Caenorhabditis elegans 456216 R-CEL-450490 https://reactome.org/PathwayBrowser/#/R-CEL-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Caenorhabditis elegans 456216 R-CEL-450499 https://reactome.org/PathwayBrowser/#/R-CEL-450499 Protein Kinase B (AKT) phosphorylates KSRP IEA Caenorhabditis elegans 456216 R-CEL-450827 https://reactome.org/PathwayBrowser/#/R-CEL-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Caenorhabditis elegans 456216 R-CEL-4793911 https://reactome.org/PathwayBrowser/#/R-CEL-4793911 MAPKAPK2 phosphorylates HSF1 IEA Caenorhabditis elegans 456216 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 456216 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 456216 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 456216 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 456216 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 456216 R-CEL-504054 https://reactome.org/PathwayBrowser/#/R-CEL-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Caenorhabditis elegans 456216 R-CEL-508040 https://reactome.org/PathwayBrowser/#/R-CEL-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Caenorhabditis elegans 456216 R-CEL-5082387 https://reactome.org/PathwayBrowser/#/R-CEL-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Caenorhabditis elegans 456216 R-CEL-5082405 https://reactome.org/PathwayBrowser/#/R-CEL-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Caenorhabditis elegans 456216 R-CEL-508308 https://reactome.org/PathwayBrowser/#/R-CEL-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Caenorhabditis elegans 456216 R-CEL-5138432 https://reactome.org/PathwayBrowser/#/R-CEL-5138432 DVL2 is phosphorylated by PKC IEA Caenorhabditis elegans 456216 R-CEL-5195402 https://reactome.org/PathwayBrowser/#/R-CEL-5195402 CDK1 phosphorylates LPIN IEA Caenorhabditis elegans 456216 R-CEL-5218804 https://reactome.org/PathwayBrowser/#/R-CEL-5218804 p38 MAPK activation by VEGFR IEA Caenorhabditis elegans 456216 R-CEL-5218805 https://reactome.org/PathwayBrowser/#/R-CEL-5218805 PKC autophosphorylates IEA Caenorhabditis elegans 456216 R-CEL-5218806 https://reactome.org/PathwayBrowser/#/R-CEL-5218806 FYN autophosphorylates IEA Caenorhabditis elegans 456216 R-CEL-5218812 https://reactome.org/PathwayBrowser/#/R-CEL-5218812 FYN phosphorylates PAK2 IEA Caenorhabditis elegans 456216 R-CEL-5218814 https://reactome.org/PathwayBrowser/#/R-CEL-5218814 PAK2 autophorylates IEA Caenorhabditis elegans 456216 R-CEL-5218819 https://reactome.org/PathwayBrowser/#/R-CEL-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 456216 R-CEL-5218821 https://reactome.org/PathwayBrowser/#/R-CEL-5218821 PDK1 phosphorylates PKC IEA Caenorhabditis elegans 456216 R-CEL-5218823 https://reactome.org/PathwayBrowser/#/R-CEL-5218823 PKC phosphorylates sphingosine kinase 1 IEA Caenorhabditis elegans 456216 R-CEL-5218854 https://reactome.org/PathwayBrowser/#/R-CEL-5218854 p-Y420-FYN is phosphorylated on S21 IEA Caenorhabditis elegans 456216 R-CEL-5218916 https://reactome.org/PathwayBrowser/#/R-CEL-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Caenorhabditis elegans 456216 R-CEL-5223317 https://reactome.org/PathwayBrowser/#/R-CEL-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 456216 R-CEL-5229343 https://reactome.org/PathwayBrowser/#/R-CEL-5229343 AXIN is phosphorylated in the destruction complex IEA Caenorhabditis elegans 456216 R-CEL-5244669 https://reactome.org/PathwayBrowser/#/R-CEL-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Caenorhabditis elegans 456216 R-CEL-5251955 https://reactome.org/PathwayBrowser/#/R-CEL-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Caenorhabditis elegans 456216 R-CEL-5251959 https://reactome.org/PathwayBrowser/#/R-CEL-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Caenorhabditis elegans 456216 R-CEL-5251989 https://reactome.org/PathwayBrowser/#/R-CEL-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Caenorhabditis elegans 456216 R-CEL-5252079 https://reactome.org/PathwayBrowser/#/R-CEL-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Caenorhabditis elegans 456216 R-CEL-5357429 https://reactome.org/PathwayBrowser/#/R-CEL-5357429 AXL autophosphorylates on Y779 and Y821 IEA Caenorhabditis elegans 456216 R-CEL-5357472 https://reactome.org/PathwayBrowser/#/R-CEL-5357472 PAK1-3 autophosphorylates IEA Caenorhabditis elegans 456216 R-CEL-5357477 https://reactome.org/PathwayBrowser/#/R-CEL-5357477 PAK1-3 phosphorylates VE-cadherin IEA Caenorhabditis elegans 456216 R-CEL-5358525 https://reactome.org/PathwayBrowser/#/R-CEL-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Caenorhabditis elegans 456216 R-CEL-5358912 https://reactome.org/PathwayBrowser/#/R-CEL-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Caenorhabditis elegans 456216 R-CEL-5444516 https://reactome.org/PathwayBrowser/#/R-CEL-5444516 Formation of MSH2:MSH6 Complex IEA Caenorhabditis elegans 456216 R-CEL-5617179 https://reactome.org/PathwayBrowser/#/R-CEL-5617179 PRKACA phosphorylates TNNI3 IEA Caenorhabditis elegans 456216 R-CEL-5618107 https://reactome.org/PathwayBrowser/#/R-CEL-5618107 ATP binding to HSP90 triggers conformation change IEA Caenorhabditis elegans 456216 R-CEL-5623667 https://reactome.org/PathwayBrowser/#/R-CEL-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Caenorhabditis elegans 456216 R-CEL-5624486 https://reactome.org/PathwayBrowser/#/R-CEL-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Caenorhabditis elegans 456216 R-CEL-5624492 https://reactome.org/PathwayBrowser/#/R-CEL-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Caenorhabditis elegans 456216 R-CEL-5627775 https://reactome.org/PathwayBrowser/#/R-CEL-5627775 Autophosphorylation of PAK1,2,3 IEA Caenorhabditis elegans 456216 R-CEL-5654149 https://reactome.org/PathwayBrowser/#/R-CEL-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Caenorhabditis elegans 456216 R-CEL-5654151 https://reactome.org/PathwayBrowser/#/R-CEL-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Caenorhabditis elegans 456216 R-CEL-5654418 https://reactome.org/PathwayBrowser/#/R-CEL-5654418 Activated FGFR4 phosphorylates FRS2 IEA Caenorhabditis elegans 456216 R-CEL-5654428 https://reactome.org/PathwayBrowser/#/R-CEL-5654428 Activated FGFR4 phosphorylates SHC1 IEA Caenorhabditis elegans 456216 R-CEL-5654560 https://reactome.org/PathwayBrowser/#/R-CEL-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Caenorhabditis elegans 456216 R-CEL-5654566 https://reactome.org/PathwayBrowser/#/R-CEL-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Caenorhabditis elegans 456216 R-CEL-5654575 https://reactome.org/PathwayBrowser/#/R-CEL-5654575 Activated FGFR1 phosphorylates FRS2 IEA Caenorhabditis elegans 456216 R-CEL-5654578 https://reactome.org/PathwayBrowser/#/R-CEL-5654578 Activated FGFR1 phosphorylates FRS3 IEA Caenorhabditis elegans 456216 R-CEL-5654582 https://reactome.org/PathwayBrowser/#/R-CEL-5654582 Activated FGFR1 phosphorylates SHC1 IEA Caenorhabditis elegans 456216 R-CEL-5654653 https://reactome.org/PathwayBrowser/#/R-CEL-5654653 Activated FGFR4 phosphorylates FRS3 IEA Caenorhabditis elegans 456216 R-CEL-5654690 https://reactome.org/PathwayBrowser/#/R-CEL-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 456216 R-CEL-5654717 https://reactome.org/PathwayBrowser/#/R-CEL-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 456216 R-CEL-5654989 https://reactome.org/PathwayBrowser/#/R-CEL-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Caenorhabditis elegans 456216 R-CEL-5662466 https://reactome.org/PathwayBrowser/#/R-CEL-5662466 XYLB phosphorylates D-xylulose IEA Caenorhabditis elegans 456216 R-CEL-5665868 https://reactome.org/PathwayBrowser/#/R-CEL-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Caenorhabditis elegans 456216 R-CEL-5668932 https://reactome.org/PathwayBrowser/#/R-CEL-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Caenorhabditis elegans 456216 R-CEL-5668947 https://reactome.org/PathwayBrowser/#/R-CEL-5668947 PAK1 phosphorylates myosin phosphatase IEA Caenorhabditis elegans 456216 R-CEL-5669250 https://reactome.org/PathwayBrowser/#/R-CEL-5669250 PAK1 phosphorylates FLNA IEA Caenorhabditis elegans 456216 R-CEL-5671749 https://reactome.org/PathwayBrowser/#/R-CEL-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Caenorhabditis elegans 456216 R-CEL-5671763 https://reactome.org/PathwayBrowser/#/R-CEL-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Caenorhabditis elegans 456216 R-CEL-5672008 https://reactome.org/PathwayBrowser/#/R-CEL-5672008 Thr-180 of ULK1 is phosphorylated IEA Caenorhabditis elegans 456216 R-CEL-5672010 https://reactome.org/PathwayBrowser/#/R-CEL-5672010 Active MTORC1 phosphorylates ULK1 IEA Caenorhabditis elegans 456216 R-CEL-5672012 https://reactome.org/PathwayBrowser/#/R-CEL-5672012 Beclin-1 complex phosphorylates PtdIns IEA Caenorhabditis elegans 456216 R-CEL-5672828 https://reactome.org/PathwayBrowser/#/R-CEL-5672828 mTORC1 phosphorylates AKT1S1 IEA Caenorhabditis elegans 456216 R-CEL-5672948 https://reactome.org/PathwayBrowser/#/R-CEL-5672948 MARK3 phosphorylates KSR1 IEA Caenorhabditis elegans 456216 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 456216 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 456216 R-CEL-5673768 https://reactome.org/PathwayBrowser/#/R-CEL-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Caenorhabditis elegans 456216 R-CEL-5674130 https://reactome.org/PathwayBrowser/#/R-CEL-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Caenorhabditis elegans 456216 R-CEL-5674373 https://reactome.org/PathwayBrowser/#/R-CEL-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Caenorhabditis elegans 456216 R-CEL-5674496 https://reactome.org/PathwayBrowser/#/R-CEL-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Caenorhabditis elegans 456216 R-CEL-5675194 https://reactome.org/PathwayBrowser/#/R-CEL-5675194 Activated MAPK phosphorylates RAF1 IEA Caenorhabditis elegans 456216 R-CEL-5675198 https://reactome.org/PathwayBrowser/#/R-CEL-5675198 Activated MAPKs phosphorylate BRAF IEA Caenorhabditis elegans 456216 R-CEL-5675868 https://reactome.org/PathwayBrowser/#/R-CEL-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Caenorhabditis elegans 456216 R-CEL-5678863 https://reactome.org/PathwayBrowser/#/R-CEL-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Caenorhabditis elegans 456216 R-CEL-5679041 https://reactome.org/PathwayBrowser/#/R-CEL-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 456216 R-CEL-5679205 https://reactome.org/PathwayBrowser/#/R-CEL-5679205 ULK1 phosphorylates Beclin-1 IEA Caenorhabditis elegans 456216 R-CEL-5682101 https://reactome.org/PathwayBrowser/#/R-CEL-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Caenorhabditis elegans 456216 R-CEL-5682285 https://reactome.org/PathwayBrowser/#/R-CEL-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Caenorhabditis elegans 456216 R-CEL-5683714 https://reactome.org/PathwayBrowser/#/R-CEL-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Caenorhabditis elegans 456216 R-CEL-5683792 https://reactome.org/PathwayBrowser/#/R-CEL-5683792 p-T68-CHEK2 autophosphorylates IEA Caenorhabditis elegans 456216 R-CEL-5685156 https://reactome.org/PathwayBrowser/#/R-CEL-5685156 ATR phosphorylates RPA2 IEA Caenorhabditis elegans 456216 R-CEL-5685230 https://reactome.org/PathwayBrowser/#/R-CEL-5685230 CHEK1 phosphorylates RAD51 IEA Caenorhabditis elegans 456216 R-CEL-5687086 https://reactome.org/PathwayBrowser/#/R-CEL-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Caenorhabditis elegans 456216 R-CEL-5690996 https://reactome.org/PathwayBrowser/#/R-CEL-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Caenorhabditis elegans 456216 R-CEL-5692462 https://reactome.org/PathwayBrowser/#/R-CEL-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Caenorhabditis elegans 456216 R-CEL-5692755 https://reactome.org/PathwayBrowser/#/R-CEL-5692755 CDK1 phosphorylates MAPK6 IEA Caenorhabditis elegans 456216 R-CEL-5696021 https://reactome.org/PathwayBrowser/#/R-CEL-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Caenorhabditis elegans 456216 R-CEL-5696074 https://reactome.org/PathwayBrowser/#/R-CEL-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Caenorhabditis elegans 456216 R-CEL-5696839 https://reactome.org/PathwayBrowser/#/R-CEL-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Caenorhabditis elegans 456216 R-CEL-6782131 https://reactome.org/PathwayBrowser/#/R-CEL-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Caenorhabditis elegans 456216 R-CEL-6787540 https://reactome.org/PathwayBrowser/#/R-CEL-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Caenorhabditis elegans 456216 R-CEL-6788810 https://reactome.org/PathwayBrowser/#/R-CEL-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 456216 R-CEL-6788855 https://reactome.org/PathwayBrowser/#/R-CEL-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Caenorhabditis elegans 456216 R-CEL-6788867 https://reactome.org/PathwayBrowser/#/R-CEL-6788867 FN3K phosphorylates ketosamines IEA Caenorhabditis elegans 456216 R-CEL-6795290 https://reactome.org/PathwayBrowser/#/R-CEL-6795290 TORC2 complex phosphorylates SGK1 IEA Caenorhabditis elegans 456216 R-CEL-6795473 https://reactome.org/PathwayBrowser/#/R-CEL-6795473 PDPK1 phosphorylates SGK1 IEA Caenorhabditis elegans 456216 R-CEL-6797606 https://reactome.org/PathwayBrowser/#/R-CEL-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Caenorhabditis elegans 456216 R-CEL-6798174 https://reactome.org/PathwayBrowser/#/R-CEL-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Caenorhabditis elegans 456216 R-CEL-6799495 https://reactome.org/PathwayBrowser/#/R-CEL-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Caenorhabditis elegans 456216 R-CEL-6801342 https://reactome.org/PathwayBrowser/#/R-CEL-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Caenorhabditis elegans 456216 R-CEL-6801456 https://reactome.org/PathwayBrowser/#/R-CEL-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Caenorhabditis elegans 456216 R-CEL-6803771 https://reactome.org/PathwayBrowser/#/R-CEL-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Caenorhabditis elegans 456216 R-CEL-6804266 https://reactome.org/PathwayBrowser/#/R-CEL-6804266 CHEK2 phosphorylates TTC5 IEA Caenorhabditis elegans 456216 R-CEL-6805640 https://reactome.org/PathwayBrowser/#/R-CEL-6805640 AKT phosphorylates KAT6A IEA Caenorhabditis elegans 456216 R-CEL-6806877 https://reactome.org/PathwayBrowser/#/R-CEL-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Caenorhabditis elegans 456216 R-CEL-6806967 https://reactome.org/PathwayBrowser/#/R-CEL-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Caenorhabditis elegans 456216 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 456216 R-CEL-6807868 https://reactome.org/PathwayBrowser/#/R-CEL-6807868 GBF1 stimulates ARF nucleotide exchange IEA Caenorhabditis elegans 456216 R-CEL-6810233 https://reactome.org/PathwayBrowser/#/R-CEL-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Caenorhabditis elegans 456216 R-CEL-6811522 https://reactome.org/PathwayBrowser/#/R-CEL-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Caenorhabditis elegans 456216 R-CEL-6814119 https://reactome.org/PathwayBrowser/#/R-CEL-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Caenorhabditis elegans 456216 R-CEL-6814120 https://reactome.org/PathwayBrowser/#/R-CEL-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Caenorhabditis elegans 456216 R-CEL-6814121 https://reactome.org/PathwayBrowser/#/R-CEL-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Caenorhabditis elegans 456216 R-CEL-6814124 https://reactome.org/PathwayBrowser/#/R-CEL-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Caenorhabditis elegans 456216 R-CEL-6814409 https://reactome.org/PathwayBrowser/#/R-CEL-6814409 CK2 phosphorylates PDCL IEA Caenorhabditis elegans 456216 R-CEL-68944 https://reactome.org/PathwayBrowser/#/R-CEL-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Caenorhabditis elegans 456216 R-CEL-69005 https://reactome.org/PathwayBrowser/#/R-CEL-69005 Cdc6 protein is phosphorylated by CDK IEA Caenorhabditis elegans 456216 R-CEL-69063 https://reactome.org/PathwayBrowser/#/R-CEL-69063 Loading of PCNA - Sliding Clamp Formation IEA Caenorhabditis elegans 456216 R-CEL-69604 https://reactome.org/PathwayBrowser/#/R-CEL-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Caenorhabditis elegans 456216 R-CEL-69608 https://reactome.org/PathwayBrowser/#/R-CEL-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Caenorhabditis elegans 456216 R-CEL-70349 https://reactome.org/PathwayBrowser/#/R-CEL-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 456216 R-CEL-70420 https://reactome.org/PathwayBrowser/#/R-CEL-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Caenorhabditis elegans 456216 R-CEL-70467 https://reactome.org/PathwayBrowser/#/R-CEL-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Caenorhabditis elegans 456216 R-CEL-70486 https://reactome.org/PathwayBrowser/#/R-CEL-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Caenorhabditis elegans 456216 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 456216 R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Caenorhabditis elegans 456216 R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Caenorhabditis elegans 456216 R-CEL-70606 https://reactome.org/PathwayBrowser/#/R-CEL-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Caenorhabditis elegans 456216 R-CEL-70773 https://reactome.org/PathwayBrowser/#/R-CEL-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Caenorhabditis elegans 456216 R-CEL-70967 https://reactome.org/PathwayBrowser/#/R-CEL-70967 IDH3 complex decarboxylates isocitrate IEA Caenorhabditis elegans 456216 R-CEL-70997 https://reactome.org/PathwayBrowser/#/R-CEL-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Caenorhabditis elegans 456216 R-CEL-71031 https://reactome.org/PathwayBrowser/#/R-CEL-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Caenorhabditis elegans 456216 R-CEL-71401 https://reactome.org/PathwayBrowser/#/R-CEL-71401 OGDH dimer decarboxylates 2-OG IEA Caenorhabditis elegans 456216 R-CEL-71541 https://reactome.org/PathwayBrowser/#/R-CEL-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Caenorhabditis elegans 456216 R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 456216 R-CEL-71802 https://reactome.org/PathwayBrowser/#/R-CEL-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Caenorhabditis elegans 456216 R-CEL-71850 https://reactome.org/PathwayBrowser/#/R-CEL-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Caenorhabditis elegans 456216 R-CEL-72621 https://reactome.org/PathwayBrowser/#/R-CEL-72621 Ribosomal scanning IEA Caenorhabditis elegans 456216 R-CEL-73548 https://reactome.org/PathwayBrowser/#/R-CEL-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Caenorhabditis elegans 456216 R-CEL-73577 https://reactome.org/PathwayBrowser/#/R-CEL-73577 CAD hexamer transforms L-Gln to CAP IEA Caenorhabditis elegans 456216 R-CEL-73599 https://reactome.org/PathwayBrowser/#/R-CEL-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Caenorhabditis elegans 456216 R-CEL-73632 https://reactome.org/PathwayBrowser/#/R-CEL-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Caenorhabditis elegans 456216 R-CEL-73635 https://reactome.org/PathwayBrowser/#/R-CEL-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Caenorhabditis elegans 456216 R-CEL-73647 https://reactome.org/PathwayBrowser/#/R-CEL-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Caenorhabditis elegans 456216 R-CEL-73788 https://reactome.org/PathwayBrowser/#/R-CEL-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Caenorhabditis elegans 456216 R-CEL-73805 https://reactome.org/PathwayBrowser/#/R-CEL-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Caenorhabditis elegans 456216 R-CEL-73810 https://reactome.org/PathwayBrowser/#/R-CEL-73810 FGAM + ATP => AIR + ADP + Pi IEA Caenorhabditis elegans 456216 R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 456216 R-CEL-73814 https://reactome.org/PathwayBrowser/#/R-CEL-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Caenorhabditis elegans 456216 R-CEL-74220 https://reactome.org/PathwayBrowser/#/R-CEL-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Caenorhabditis elegans 456216 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 456216 R-CEL-75010 https://reactome.org/PathwayBrowser/#/R-CEL-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Caenorhabditis elegans 456216 R-CEL-75125 https://reactome.org/PathwayBrowser/#/R-CEL-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Caenorhabditis elegans 456216 R-CEL-75126 https://reactome.org/PathwayBrowser/#/R-CEL-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Caenorhabditis elegans 456216 R-CEL-75809 https://reactome.org/PathwayBrowser/#/R-CEL-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Caenorhabditis elegans 456216 R-CEL-75848 https://reactome.org/PathwayBrowser/#/R-CEL-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Caenorhabditis elegans 456216 R-CEL-75851 https://reactome.org/PathwayBrowser/#/R-CEL-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 456216 R-CEL-75887 https://reactome.org/PathwayBrowser/#/R-CEL-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Caenorhabditis elegans 456216 R-CEL-75949 https://reactome.org/PathwayBrowser/#/R-CEL-75949 RNA Polymerase II Promoter Opening: First Transition IEA Caenorhabditis elegans 456216 R-CEL-77071 https://reactome.org/PathwayBrowser/#/R-CEL-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Caenorhabditis elegans 456216 R-CEL-8847977 https://reactome.org/PathwayBrowser/#/R-CEL-8847977 FRK phosphorylates PTEN IEA Caenorhabditis elegans 456216 R-CEL-8848005 https://reactome.org/PathwayBrowser/#/R-CEL-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Caenorhabditis elegans 456216 R-CEL-8848758 https://reactome.org/PathwayBrowser/#/R-CEL-8848758 PTK6 phosphorylates AKT1 IEA Caenorhabditis elegans 456216 R-CEL-8848776 https://reactome.org/PathwayBrowser/#/R-CEL-8848776 PTK6 phosphorylates DOK1 IEA Caenorhabditis elegans 456216 R-CEL-8848818 https://reactome.org/PathwayBrowser/#/R-CEL-8848818 PTK6 phosphorylates CBL IEA Caenorhabditis elegans 456216 R-CEL-8848873 https://reactome.org/PathwayBrowser/#/R-CEL-8848873 PTK6 phosphorylates ARAP1 IEA Caenorhabditis elegans 456216 R-CEL-8849068 https://reactome.org/PathwayBrowser/#/R-CEL-8849068 PTK6 phosphorylates ARHGAP35 IEA Caenorhabditis elegans 456216 R-CEL-8849102 https://reactome.org/PathwayBrowser/#/R-CEL-8849102 SRMS phosphorylates PTK6 IEA Caenorhabditis elegans 456216 R-CEL-8849353 https://reactome.org/PathwayBrowser/#/R-CEL-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Caenorhabditis elegans 456216 R-CEL-8849463 https://reactome.org/PathwayBrowser/#/R-CEL-8849463 PTK6 phosphorylates SFPQ IEA Caenorhabditis elegans 456216 R-CEL-8850527 https://reactome.org/PathwayBrowser/#/R-CEL-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Caenorhabditis elegans 456216 R-CEL-8850529 https://reactome.org/PathwayBrowser/#/R-CEL-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Caenorhabditis elegans 456216 R-CEL-8850534 https://reactome.org/PathwayBrowser/#/R-CEL-8850534 PDCL promotes G-protein beta 5 folding IEA Caenorhabditis elegans 456216 R-CEL-8850539 https://reactome.org/PathwayBrowser/#/R-CEL-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Caenorhabditis elegans 456216 R-CEL-8850945 https://reactome.org/PathwayBrowser/#/R-CEL-8850945 Casein kinase II phosphorylates PTEN IEA Caenorhabditis elegans 456216 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 456216 R-CEL-8851933 https://reactome.org/PathwayBrowser/#/R-CEL-8851933 MET phosphorylates GAB1 IEA Caenorhabditis elegans 456216 R-CEL-8852019 https://reactome.org/PathwayBrowser/#/R-CEL-8852019 MET bound PI3K generates PIP3 IEA Caenorhabditis elegans 456216 R-CEL-8852552 https://reactome.org/PathwayBrowser/#/R-CEL-8852552 MST1R autophosphorylates IEA Caenorhabditis elegans 456216 R-CEL-8856813 https://reactome.org/PathwayBrowser/#/R-CEL-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Caenorhabditis elegans 456216 R-CEL-8857925 https://reactome.org/PathwayBrowser/#/R-CEL-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Caenorhabditis elegans 456216 R-CEL-8866542 https://reactome.org/PathwayBrowser/#/R-CEL-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Caenorhabditis elegans 456216 R-CEL-8867041 https://reactome.org/PathwayBrowser/#/R-CEL-8867041 EGFR phosphorylates EPS15 IEA Caenorhabditis elegans 456216 R-CEL-8868066 https://reactome.org/PathwayBrowser/#/R-CEL-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Caenorhabditis elegans 456216 R-CEL-8868072 https://reactome.org/PathwayBrowser/#/R-CEL-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Caenorhabditis elegans 456216 R-CEL-8868118 https://reactome.org/PathwayBrowser/#/R-CEL-8868118 MAPK12 phosphorylates PTPN3 IEA Caenorhabditis elegans 456216 R-CEL-8868658 https://reactome.org/PathwayBrowser/#/R-CEL-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Caenorhabditis elegans 456216 R-CEL-8873929 https://reactome.org/PathwayBrowser/#/R-CEL-8873929 Casein kinase II phosphorylates STARD10 IEA Caenorhabditis elegans 456216 R-CEL-8874078 https://reactome.org/PathwayBrowser/#/R-CEL-8874078 PTK2 autophosphorylates IEA Caenorhabditis elegans 456216 R-CEL-8874080 https://reactome.org/PathwayBrowser/#/R-CEL-8874080 SRC phosphorylates PTK2 IEA Caenorhabditis elegans 456216 R-CEL-8874082 https://reactome.org/PathwayBrowser/#/R-CEL-8874082 MET phosphorylates PTK2 IEA Caenorhabditis elegans 456216 R-CEL-8875451 https://reactome.org/PathwayBrowser/#/R-CEL-8875451 MET phosphorylates CBL IEA Caenorhabditis elegans 456216 R-CEL-8875817 https://reactome.org/PathwayBrowser/#/R-CEL-8875817 MET phosphorylates STAT3 IEA Caenorhabditis elegans 456216 R-CEL-8876889 https://reactome.org/PathwayBrowser/#/R-CEL-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 456216 R-CEL-8877691 https://reactome.org/PathwayBrowser/#/R-CEL-8877691 MAP2K6 phosphorylates PIP4K2B IEA Caenorhabditis elegans 456216 R-CEL-8878050 https://reactome.org/PathwayBrowser/#/R-CEL-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Caenorhabditis elegans 456216 R-CEL-8878054 https://reactome.org/PathwayBrowser/#/R-CEL-8878054 HIPK2 phosphorylates RUNX1 IEA Caenorhabditis elegans 456216 R-CEL-8933446 https://reactome.org/PathwayBrowser/#/R-CEL-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Caenorhabditis elegans 456216 R-CEL-8937807 https://reactome.org/PathwayBrowser/#/R-CEL-8937807 SRC phosphorylates RUNX3 IEA Caenorhabditis elegans 456216 R-CEL-8944454 https://reactome.org/PathwayBrowser/#/R-CEL-8944454 mTORC1 phosphorylates MAF1 IEA Caenorhabditis elegans 456216 R-CEL-8948039 https://reactome.org/PathwayBrowser/#/R-CEL-8948039 FUNDC1 is phosphorylated by CK2 IEA Caenorhabditis elegans 456216 R-CEL-8948143 https://reactome.org/PathwayBrowser/#/R-CEL-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Caenorhabditis elegans 456216 R-CEL-8948146 https://reactome.org/PathwayBrowser/#/R-CEL-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Caenorhabditis elegans 456216 R-CEL-8948757 https://reactome.org/PathwayBrowser/#/R-CEL-8948757 AKT phosphorylates MKRN1 IEA Caenorhabditis elegans 456216 R-CEL-8952289 https://reactome.org/PathwayBrowser/#/R-CEL-8952289 FAM20C phosphorylates FAM20C substrates IEA Caenorhabditis elegans 456216 R-CEL-8954327 https://reactome.org/PathwayBrowser/#/R-CEL-8954327 UCKL1 phosphorylates urindine, cytidine IEA Caenorhabditis elegans 456216 R-CEL-8955030 https://reactome.org/PathwayBrowser/#/R-CEL-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Caenorhabditis elegans 456216 R-CEL-8955844 https://reactome.org/PathwayBrowser/#/R-CEL-8955844 RBKS phosphorylates ribose to R5P IEA Caenorhabditis elegans 456216 R-CEL-8956659 https://reactome.org/PathwayBrowser/#/R-CEL-8956659 ABL1 phosphorylates YAP1 IEA Caenorhabditis elegans 456216 R-CEL-8959719 https://reactome.org/PathwayBrowser/#/R-CEL-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Caenorhabditis elegans 456216 R-CEL-8964242 https://reactome.org/PathwayBrowser/#/R-CEL-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Caenorhabditis elegans 456216 R-CEL-9008043 https://reactome.org/PathwayBrowser/#/R-CEL-9008043 MAPK8 phosphorylation IEA Caenorhabditis elegans 456216 R-CEL-9009072 https://reactome.org/PathwayBrowser/#/R-CEL-9009072 STAT3 phosphorylation IEA Caenorhabditis elegans 456216 R-CEL-9009282 https://reactome.org/PathwayBrowser/#/R-CEL-9009282 CDK1 phosphorylates RUNX2 IEA Caenorhabditis elegans 456216 R-CEL-9012319 https://reactome.org/PathwayBrowser/#/R-CEL-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Caenorhabditis elegans 456216 R-CEL-9021357 https://reactome.org/PathwayBrowser/#/R-CEL-9021357 PRKCI phosphorylates ELF3 IEA Caenorhabditis elegans 456216 R-CEL-913996 https://reactome.org/PathwayBrowser/#/R-CEL-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Caenorhabditis elegans 456216 R-CEL-917841 https://reactome.org/PathwayBrowser/#/R-CEL-917841 Acidification of Tf:TfR1 containing endosome IEA Caenorhabditis elegans 456216 R-CEL-917979 https://reactome.org/PathwayBrowser/#/R-CEL-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Caenorhabditis elegans 456216 R-CEL-927889 https://reactome.org/PathwayBrowser/#/R-CEL-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Caenorhabditis elegans 456216 R-CEL-936883 https://reactome.org/PathwayBrowser/#/R-CEL-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Caenorhabditis elegans 456216 R-CEL-936895 https://reactome.org/PathwayBrowser/#/R-CEL-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Caenorhabditis elegans 456216 R-CEL-939763 https://reactome.org/PathwayBrowser/#/R-CEL-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Caenorhabditis elegans 456216 R-CEL-947591 https://reactome.org/PathwayBrowser/#/R-CEL-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Caenorhabditis elegans 456216 R-CEL-9604328 https://reactome.org/PathwayBrowser/#/R-CEL-9604328 AKT1 phosphorylates NOTCH4 IEA Caenorhabditis elegans 456216 R-CEL-9610153 https://reactome.org/PathwayBrowser/#/R-CEL-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Caenorhabditis elegans 456216 R-CEL-9610156 https://reactome.org/PathwayBrowser/#/R-CEL-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Caenorhabditis elegans 456216 R-CEL-9610163 https://reactome.org/PathwayBrowser/#/R-CEL-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Caenorhabditis elegans 456216 R-CEL-9612501 https://reactome.org/PathwayBrowser/#/R-CEL-9612501 SGK phosphorylates CREB1 IEA Caenorhabditis elegans 456216 R-CEL-9612509 https://reactome.org/PathwayBrowser/#/R-CEL-9612509 SGK phosphorylates SRF IEA Caenorhabditis elegans 456216 R-CEL-9619355 https://reactome.org/PathwayBrowser/#/R-CEL-9619355 CaMKK autophosphorylates in the cytosol IEA Caenorhabditis elegans 456216 R-CEL-9624526 https://reactome.org/PathwayBrowser/#/R-CEL-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Caenorhabditis elegans 456216 R-CEL-9625487 https://reactome.org/PathwayBrowser/#/R-CEL-9625487 PTK2 autophosphorylates downstream of EGFR IEA Caenorhabditis elegans 456216 R-CEL-9632858 https://reactome.org/PathwayBrowser/#/R-CEL-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Caenorhabditis elegans 456216 R-CEL-9648089 https://reactome.org/PathwayBrowser/#/R-CEL-9648089 NEK6 and NEK7 phosphorylate EML4 IEA Caenorhabditis elegans 456216 R-CEL-964958 https://reactome.org/PathwayBrowser/#/R-CEL-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Caenorhabditis elegans 456216 R-CEL-964962 https://reactome.org/PathwayBrowser/#/R-CEL-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Caenorhabditis elegans 456216 R-CEL-964970 https://reactome.org/PathwayBrowser/#/R-CEL-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Caenorhabditis elegans 456216 R-CEL-9653503 https://reactome.org/PathwayBrowser/#/R-CEL-9653503 KRAS4B is phosphorylated on serine 181 IEA Caenorhabditis elegans 456216 R-CEL-9661417 https://reactome.org/PathwayBrowser/#/R-CEL-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 456216 R-CEL-9684118 https://reactome.org/PathwayBrowser/#/R-CEL-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Caenorhabditis elegans 456216 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 456216 R-CEL-9699579 https://reactome.org/PathwayBrowser/#/R-CEL-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Caenorhabditis elegans 456216 R-CEL-9706399 https://reactome.org/PathwayBrowser/#/R-CEL-9706399 RHOBTB3 hydrolyzes ATP IEA Caenorhabditis elegans 456216 R-CEL-9731111 https://reactome.org/PathwayBrowser/#/R-CEL-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Caenorhabditis elegans 456216 R-CEL-9734547 https://reactome.org/PathwayBrowser/#/R-CEL-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Caenorhabditis elegans 456216 R-CEL-9748949 https://reactome.org/PathwayBrowser/#/R-CEL-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Caenorhabditis elegans 456216 R-CEL-9748963 https://reactome.org/PathwayBrowser/#/R-CEL-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Caenorhabditis elegans 456216 R-CEL-9748969 https://reactome.org/PathwayBrowser/#/R-CEL-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Caenorhabditis elegans 456216 R-CEL-9748999 https://reactome.org/PathwayBrowser/#/R-CEL-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Caenorhabditis elegans 456216 R-CEL-9750546 https://reactome.org/PathwayBrowser/#/R-CEL-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 456216 R-CEL-9750617 https://reactome.org/PathwayBrowser/#/R-CEL-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 456216 R-CEL-9750656 https://reactome.org/PathwayBrowser/#/R-CEL-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Caenorhabditis elegans 456216 R-CEL-9753278 https://reactome.org/PathwayBrowser/#/R-CEL-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 456216 R-CEL-9753283 https://reactome.org/PathwayBrowser/#/R-CEL-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 456216 R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 456216 R-CEL-9754974 https://reactome.org/PathwayBrowser/#/R-CEL-9754974 ADK phosphorylates RBV IEA Caenorhabditis elegans 456216 R-CEL-9755013 https://reactome.org/PathwayBrowser/#/R-CEL-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Caenorhabditis elegans 456216 R-CEL-9762094 https://reactome.org/PathwayBrowser/#/R-CEL-9762094 GSK3B phosphorylates p-NFE2L2 IEA Caenorhabditis elegans 456216 R-CEL-9770141 https://reactome.org/PathwayBrowser/#/R-CEL-9770141 Formation of the Spliceosomal C* complex IEA Caenorhabditis elegans 456216 R-CEL-9794120 https://reactome.org/PathwayBrowser/#/R-CEL-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Caenorhabditis elegans 456216 R-CEL-9794572 https://reactome.org/PathwayBrowser/#/R-CEL-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Caenorhabditis elegans 456216 R-CEL-9796053 https://reactome.org/PathwayBrowser/#/R-CEL-9796053 PRKCI phosphorylates NFE2L2 IEA Caenorhabditis elegans 456216 R-CEL-9796067 https://reactome.org/PathwayBrowser/#/R-CEL-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Caenorhabditis elegans 456216 R-CEL-9824977 https://reactome.org/PathwayBrowser/#/R-CEL-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Caenorhabditis elegans 456216 R-CEL-9824994 https://reactome.org/PathwayBrowser/#/R-CEL-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Caenorhabditis elegans 456216 R-CEL-9824995 https://reactome.org/PathwayBrowser/#/R-CEL-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Caenorhabditis elegans 456216 R-CEL-9824999 https://reactome.org/PathwayBrowser/#/R-CEL-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Caenorhabditis elegans 456216 R-CEL-983144 https://reactome.org/PathwayBrowser/#/R-CEL-983144 Transport of Antigen peptide in to ER IEA Caenorhabditis elegans 456216 R-CEL-983259 https://reactome.org/PathwayBrowser/#/R-CEL-983259 Kinesins move along microtubules consuming ATP IEA Caenorhabditis elegans 456216 R-CEL-9836159 https://reactome.org/PathwayBrowser/#/R-CEL-9836159 p-PKR dimer phosphorylates DHX9 IEA Caenorhabditis elegans 456216 R-CEL-9836184 https://reactome.org/PathwayBrowser/#/R-CEL-9836184 p-PKR dimer phosphorylates CDK1 IEA Caenorhabditis elegans 456216 R-CEL-9836322 https://reactome.org/PathwayBrowser/#/R-CEL-9836322 p-PKR dimer phosphorylates MKK6 IEA Caenorhabditis elegans 456216 R-CEL-9836383 https://reactome.org/PathwayBrowser/#/R-CEL-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Caenorhabditis elegans 456216 R-CEL-9836617 https://reactome.org/PathwayBrowser/#/R-CEL-9836617 p-PKR dimer phosphorylates SPHK1 IEA Caenorhabditis elegans 456216 R-CEL-9836664 https://reactome.org/PathwayBrowser/#/R-CEL-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Caenorhabditis elegans 456216 R-CEL-9837333 https://reactome.org/PathwayBrowser/#/R-CEL-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Caenorhabditis elegans 456216 R-CEL-9837337 https://reactome.org/PathwayBrowser/#/R-CEL-9837337 DCAKD phosphorylates DP-CoA IEA Caenorhabditis elegans 456216 R-CEL-9838004 https://reactome.org/PathwayBrowser/#/R-CEL-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Caenorhabditis elegans 456216 R-CEL-9838081 https://reactome.org/PathwayBrowser/#/R-CEL-9838081 LONP1 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 456216 R-CEL-9838289 https://reactome.org/PathwayBrowser/#/R-CEL-9838289 CLPXP degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 456216 R-CEL-9838321 https://reactome.org/PathwayBrowser/#/R-CEL-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Caenorhabditis elegans 456216 R-CEL-9839059 https://reactome.org/PathwayBrowser/#/R-CEL-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Caenorhabditis elegans 456216 R-CEL-9839105 https://reactome.org/PathwayBrowser/#/R-CEL-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 456216 R-CEL-9839113 https://reactome.org/PathwayBrowser/#/R-CEL-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Caenorhabditis elegans 456216 R-CEL-9843721 https://reactome.org/PathwayBrowser/#/R-CEL-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Caenorhabditis elegans 456216 R-CFA-1008248 https://reactome.org/PathwayBrowser/#/R-CFA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Canis familiaris 456216 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 456216 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 456216 R-CFA-109415 https://reactome.org/PathwayBrowser/#/R-CFA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Canis familiaris 456216 R-CFA-109624 https://reactome.org/PathwayBrowser/#/R-CFA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Canis familiaris 456216 R-CFA-109671 https://reactome.org/PathwayBrowser/#/R-CFA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Canis familiaris 456216 R-CFA-109699 https://reactome.org/PathwayBrowser/#/R-CFA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-109759 https://reactome.org/PathwayBrowser/#/R-CFA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Canis familiaris 456216 R-CFA-109822 https://reactome.org/PathwayBrowser/#/R-CFA-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Canis familiaris 456216 R-CFA-109823 https://reactome.org/PathwayBrowser/#/R-CFA-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Canis familiaris 456216 R-CFA-109862 https://reactome.org/PathwayBrowser/#/R-CFA-109862 MAP2K2 phosphorylates MAPK1 IEA Canis familiaris 456216 R-CFA-109903 https://reactome.org/PathwayBrowser/#/R-CFA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Canis familiaris 456216 R-CFA-110133 https://reactome.org/PathwayBrowser/#/R-CFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Canis familiaris 456216 R-CFA-110137 https://reactome.org/PathwayBrowser/#/R-CFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Canis familiaris 456216 R-CFA-110138 https://reactome.org/PathwayBrowser/#/R-CFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 456216 R-CFA-110141 https://reactome.org/PathwayBrowser/#/R-CFA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Canis familiaris 456216 R-CFA-110144 https://reactome.org/PathwayBrowser/#/R-CFA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Canis familiaris 456216 R-CFA-110145 https://reactome.org/PathwayBrowser/#/R-CFA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Canis familiaris 456216 R-CFA-1112510 https://reactome.org/PathwayBrowser/#/R-CFA-1112510 IL6ST is tyrosine phosphorylated IEA Canis familiaris 456216 R-CFA-1112514 https://reactome.org/PathwayBrowser/#/R-CFA-1112514 JAK activation IEA Canis familiaris 456216 R-CFA-1112602 https://reactome.org/PathwayBrowser/#/R-CFA-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Canis familiaris 456216 R-CFA-1112703 https://reactome.org/PathwayBrowser/#/R-CFA-1112703 PTPN11 is phosphorylated IEA Canis familiaris 456216 R-CFA-1112727 https://reactome.org/PathwayBrowser/#/R-CFA-1112727 Serine phosphorylation of STATs IEA Canis familiaris 456216 R-CFA-111898 https://reactome.org/PathwayBrowser/#/R-CFA-111898 Phosphorylation of cPLA2 by ERK-2 IEA Canis familiaris 456216 R-CFA-111970 https://reactome.org/PathwayBrowser/#/R-CFA-111970 PKC phosphorylates GRK2 IEA Canis familiaris 456216 R-CFA-112381 https://reactome.org/PathwayBrowser/#/R-CFA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Canis familiaris 456216 R-CFA-114252 https://reactome.org/PathwayBrowser/#/R-CFA-114252 Cleavage of Procaspase-3 by the apoptosome IEA Canis familiaris 456216 R-CFA-114254 https://reactome.org/PathwayBrowser/#/R-CFA-114254 CYCS binds to APAF1 IEA Canis familiaris 456216 R-CFA-114259 https://reactome.org/PathwayBrowser/#/R-CFA-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Canis familiaris 456216 R-CFA-114261 https://reactome.org/PathwayBrowser/#/R-CFA-114261 Cleavage of Procaspase-7 by the apoptosome IEA Canis familiaris 456216 R-CFA-114600 https://reactome.org/PathwayBrowser/#/R-CFA-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Canis familiaris 456216 R-CFA-114683 https://reactome.org/PathwayBrowser/#/R-CFA-114683 Phosphorylation of Platelet Sec-1 IEA Canis familiaris 456216 R-CFA-114684 https://reactome.org/PathwayBrowser/#/R-CFA-114684 Phosphorylation of Syntaxin-4 IEA Canis familiaris 456216 R-CFA-1168459 https://reactome.org/PathwayBrowser/#/R-CFA-1168459 Lyn activates ERK IEA Canis familiaris 456216 R-CFA-1168635 https://reactome.org/PathwayBrowser/#/R-CFA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Canis familiaris 456216 R-CFA-1168638 https://reactome.org/PathwayBrowser/#/R-CFA-1168638 Activated IKK phosphorylates I-kappaB IEA Canis familiaris 456216 R-CFA-1181149 https://reactome.org/PathwayBrowser/#/R-CFA-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Canis familiaris 456216 R-CFA-1226094 https://reactome.org/PathwayBrowser/#/R-CFA-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Canis familiaris 456216 R-CFA-1226095 https://reactome.org/PathwayBrowser/#/R-CFA-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Canis familiaris 456216 R-CFA-1247935 https://reactome.org/PathwayBrowser/#/R-CFA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Canis familiaris 456216 R-CFA-1247960 https://reactome.org/PathwayBrowser/#/R-CFA-1247960 Activation of p38 MAPK IEA Canis familiaris 456216 R-CFA-1250195 https://reactome.org/PathwayBrowser/#/R-CFA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Canis familiaris 456216 R-CFA-1250315 https://reactome.org/PathwayBrowser/#/R-CFA-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Canis familiaris 456216 R-CFA-1250348 https://reactome.org/PathwayBrowser/#/R-CFA-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Canis familiaris 456216 R-CFA-1250370 https://reactome.org/PathwayBrowser/#/R-CFA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Canis familiaris 456216 R-CFA-1250462 https://reactome.org/PathwayBrowser/#/R-CFA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Canis familiaris 456216 R-CFA-1295540 https://reactome.org/PathwayBrowser/#/R-CFA-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Canis familiaris 456216 R-CFA-1295609 https://reactome.org/PathwayBrowser/#/R-CFA-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Canis familiaris 456216 R-CFA-1306957 https://reactome.org/PathwayBrowser/#/R-CFA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Canis familiaris 456216 R-CFA-1306979 https://reactome.org/PathwayBrowser/#/R-CFA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Canis familiaris 456216 R-CFA-1307963 https://reactome.org/PathwayBrowser/#/R-CFA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Canis familiaris 456216 R-CFA-1362270 https://reactome.org/PathwayBrowser/#/R-CFA-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Canis familiaris 456216 R-CFA-1369065 https://reactome.org/PathwayBrowser/#/R-CFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Canis familiaris 456216 R-CFA-1370505 https://reactome.org/PathwayBrowser/#/R-CFA-1370505 PRLR is phosphorylated at Ser-349 IEA Canis familiaris 456216 R-CFA-139908 https://reactome.org/PathwayBrowser/#/R-CFA-139908 Phosphorylation of DLC2 by MAPK8 IEA Canis familiaris 456216 R-CFA-139918 https://reactome.org/PathwayBrowser/#/R-CFA-139918 Phosphorylation of BIM by JNK IEA Canis familiaris 456216 R-CFA-1433418 https://reactome.org/PathwayBrowser/#/R-CFA-1433418 Phosphorylation of JAK2 IEA Canis familiaris 456216 R-CFA-1433454 https://reactome.org/PathwayBrowser/#/R-CFA-1433454 Phosphorylation of GAB2 by SFKs IEA Canis familiaris 456216 R-CFA-1433488 https://reactome.org/PathwayBrowser/#/R-CFA-1433488 Phosphorylation of SHP2 by SFKs IEA Canis familiaris 456216 R-CFA-1433506 https://reactome.org/PathwayBrowser/#/R-CFA-1433506 Phosphorylation of APS IEA Canis familiaris 456216 R-CFA-1433508 https://reactome.org/PathwayBrowser/#/R-CFA-1433508 PKC alpha interacts with and phosphorylates KIT IEA Canis familiaris 456216 R-CFA-1433514 https://reactome.org/PathwayBrowser/#/R-CFA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Canis familiaris 456216 R-CFA-1433542 https://reactome.org/PathwayBrowser/#/R-CFA-1433542 Phosphorylation and activation of VAV1 IEA Canis familiaris 456216 R-CFA-1454916 https://reactome.org/PathwayBrowser/#/R-CFA-1454916 The ABCC family mediates organic anion transport IEA Canis familiaris 456216 R-CFA-1454928 https://reactome.org/PathwayBrowser/#/R-CFA-1454928 ABCG4 may mediate cholesterol efflux IEA Canis familiaris 456216 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-1467466 https://reactome.org/PathwayBrowser/#/R-CFA-1467466 ABCA4 mediates atRAL transport IEA Canis familiaris 456216 R-CFA-1470009 https://reactome.org/PathwayBrowser/#/R-CFA-1470009 Phosphorylation of STATs IEA Canis familiaris 456216 R-CFA-1472121 https://reactome.org/PathwayBrowser/#/R-CFA-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Canis familiaris 456216 R-CFA-1483004 https://reactome.org/PathwayBrowser/#/R-CFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Canis familiaris 456216 R-CFA-1483222 https://reactome.org/PathwayBrowser/#/R-CFA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Canis familiaris 456216 R-CFA-1497853 https://reactome.org/PathwayBrowser/#/R-CFA-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Canis familiaris 456216 R-CFA-1524186 https://reactome.org/PathwayBrowser/#/R-CFA-1524186 Phosphorylation of PLCgamma by PDGFR IEA Canis familiaris 456216 R-CFA-1549526 https://reactome.org/PathwayBrowser/#/R-CFA-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Canis familiaris 456216 R-CFA-156673 https://reactome.org/PathwayBrowser/#/R-CFA-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Canis familiaris 456216 R-CFA-156678 https://reactome.org/PathwayBrowser/#/R-CFA-156678 Activation of Cdc25C IEA Canis familiaris 456216 R-CFA-156682 https://reactome.org/PathwayBrowser/#/R-CFA-156682 PLK1 phosphorylates NUDC IEA Canis familiaris 456216 R-CFA-156699 https://reactome.org/PathwayBrowser/#/R-CFA-156699 Inactivation of Wee1 kinase IEA Canis familiaris 456216 R-CFA-156723 https://reactome.org/PathwayBrowser/#/R-CFA-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Canis familiaris 456216 R-CFA-162657 https://reactome.org/PathwayBrowser/#/R-CFA-162657 Inactivation of Myt1 kinase IEA Canis familiaris 456216 R-CFA-163010 https://reactome.org/PathwayBrowser/#/R-CFA-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Canis familiaris 456216 R-CFA-163215 https://reactome.org/PathwayBrowser/#/R-CFA-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Canis familiaris 456216 R-CFA-1632857 https://reactome.org/PathwayBrowser/#/R-CFA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Canis familiaris 456216 R-CFA-1638803 https://reactome.org/PathwayBrowser/#/R-CFA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Canis familiaris 456216 R-CFA-1638845 https://reactome.org/PathwayBrowser/#/R-CFA-1638845 CERK phosphorylates CERA to form C1P IEA Canis familiaris 456216 R-CFA-164832 https://reactome.org/PathwayBrowser/#/R-CFA-164832 ATPase synthesizes ATP IEA Canis familiaris 456216 R-CFA-164840 https://reactome.org/PathwayBrowser/#/R-CFA-164840 ADP and Pi bind to ATPase IEA Canis familiaris 456216 R-CFA-165692 https://reactome.org/PathwayBrowser/#/R-CFA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Canis familiaris 456216 R-CFA-165718 https://reactome.org/PathwayBrowser/#/R-CFA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Canis familiaris 456216 R-CFA-165726 https://reactome.org/PathwayBrowser/#/R-CFA-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Canis familiaris 456216 R-CFA-165758 https://reactome.org/PathwayBrowser/#/R-CFA-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Canis familiaris 456216 R-CFA-165766 https://reactome.org/PathwayBrowser/#/R-CFA-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Canis familiaris 456216 R-CFA-165777 https://reactome.org/PathwayBrowser/#/R-CFA-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Canis familiaris 456216 R-CFA-166245 https://reactome.org/PathwayBrowser/#/R-CFA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Canis familiaris 456216 R-CFA-1675773 https://reactome.org/PathwayBrowser/#/R-CFA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Canis familiaris 456216 R-CFA-1675776 https://reactome.org/PathwayBrowser/#/R-CFA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Canis familiaris 456216 R-CFA-1675780 https://reactome.org/PathwayBrowser/#/R-CFA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Canis familiaris 456216 R-CFA-1675810 https://reactome.org/PathwayBrowser/#/R-CFA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Canis familiaris 456216 R-CFA-1675813 https://reactome.org/PathwayBrowser/#/R-CFA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Canis familiaris 456216 R-CFA-1675883 https://reactome.org/PathwayBrowser/#/R-CFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Canis familiaris 456216 R-CFA-1675928 https://reactome.org/PathwayBrowser/#/R-CFA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Canis familiaris 456216 R-CFA-1675939 https://reactome.org/PathwayBrowser/#/R-CFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Canis familiaris 456216 R-CFA-1675961 https://reactome.org/PathwayBrowser/#/R-CFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Canis familiaris 456216 R-CFA-1675974 https://reactome.org/PathwayBrowser/#/R-CFA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Canis familiaris 456216 R-CFA-1676024 https://reactome.org/PathwayBrowser/#/R-CFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Canis familiaris 456216 R-CFA-1676048 https://reactome.org/PathwayBrowser/#/R-CFA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Canis familiaris 456216 R-CFA-1676082 https://reactome.org/PathwayBrowser/#/R-CFA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Canis familiaris 456216 R-CFA-1676109 https://reactome.org/PathwayBrowser/#/R-CFA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Canis familiaris 456216 R-CFA-1676134 https://reactome.org/PathwayBrowser/#/R-CFA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Canis familiaris 456216 R-CFA-1676145 https://reactome.org/PathwayBrowser/#/R-CFA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Canis familiaris 456216 R-CFA-1676185 https://reactome.org/PathwayBrowser/#/R-CFA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Canis familiaris 456216 R-CFA-1676206 https://reactome.org/PathwayBrowser/#/R-CFA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Canis familiaris 456216 R-CFA-1678944 https://reactome.org/PathwayBrowser/#/R-CFA-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Canis familiaris 456216 R-CFA-168053 https://reactome.org/PathwayBrowser/#/R-CFA-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Canis familiaris 456216 R-CFA-168136 https://reactome.org/PathwayBrowser/#/R-CFA-168136 Activated JNKs phosphorylate c-JUN IEA Canis familiaris 456216 R-CFA-168140 https://reactome.org/PathwayBrowser/#/R-CFA-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Canis familiaris 456216 R-CFA-168162 https://reactome.org/PathwayBrowser/#/R-CFA-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Canis familiaris 456216 R-CFA-169905 https://reactome.org/PathwayBrowser/#/R-CFA-169905 ARMS is phosphorylated by active TrkA receptor IEA Canis familiaris 456216 R-CFA-170026 https://reactome.org/PathwayBrowser/#/R-CFA-170026 Protons are translocated from the intermembrane space to the matrix IEA Canis familiaris 456216 R-CFA-170055 https://reactome.org/PathwayBrowser/#/R-CFA-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Canis familiaris 456216 R-CFA-170070 https://reactome.org/PathwayBrowser/#/R-CFA-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Canis familiaris 456216 R-CFA-170076 https://reactome.org/PathwayBrowser/#/R-CFA-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Canis familiaris 456216 R-CFA-170087 https://reactome.org/PathwayBrowser/#/R-CFA-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Canis familiaris 456216 R-CFA-170126 https://reactome.org/PathwayBrowser/#/R-CFA-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Canis familiaris 456216 R-CFA-170843 https://reactome.org/PathwayBrowser/#/R-CFA-170843 TGFBR2 phosphorylates TGFBR1 IEA Canis familiaris 456216 R-CFA-170868 https://reactome.org/PathwayBrowser/#/R-CFA-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Canis familiaris 456216 R-CFA-170977 https://reactome.org/PathwayBrowser/#/R-CFA-170977 FRS2 is phosphorylated by active TrkA receptor IEA Canis familiaris 456216 R-CFA-174079 https://reactome.org/PathwayBrowser/#/R-CFA-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Canis familiaris 456216 R-CFA-174122 https://reactome.org/PathwayBrowser/#/R-CFA-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Canis familiaris 456216 R-CFA-174164 https://reactome.org/PathwayBrowser/#/R-CFA-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Canis familiaris 456216 R-CFA-174174 https://reactome.org/PathwayBrowser/#/R-CFA-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Canis familiaris 456216 R-CFA-174251 https://reactome.org/PathwayBrowser/#/R-CFA-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Canis familiaris 456216 R-CFA-174367 https://reactome.org/PathwayBrowser/#/R-CFA-174367 GCL ligates L-Glu to L-Cys IEA Canis familiaris 456216 R-CFA-174389 https://reactome.org/PathwayBrowser/#/R-CFA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Canis familiaris 456216 R-CFA-174394 https://reactome.org/PathwayBrowser/#/R-CFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Canis familiaris 456216 R-CFA-174438 https://reactome.org/PathwayBrowser/#/R-CFA-174438 Formation of the Flap Intermediate on the C-strand IEA Canis familiaris 456216 R-CFA-174439 https://reactome.org/PathwayBrowser/#/R-CFA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Canis familiaris 456216 R-CFA-176116 https://reactome.org/PathwayBrowser/#/R-CFA-176116 Recruitment and activation of Chk1 IEA Canis familiaris 456216 R-CFA-176298 https://reactome.org/PathwayBrowser/#/R-CFA-176298 Activation of claspin IEA Canis familiaris 456216 R-CFA-177275 https://reactome.org/PathwayBrowser/#/R-CFA-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Canis familiaris 456216 R-CFA-177284 https://reactome.org/PathwayBrowser/#/R-CFA-177284 PKA phosphorylates PDE4B IEA Canis familiaris 456216 R-CFA-177930 https://reactome.org/PathwayBrowser/#/R-CFA-177930 GAB1 phosphorylation by EGFR kinase IEA Canis familiaris 456216 R-CFA-177933 https://reactome.org/PathwayBrowser/#/R-CFA-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Canis familiaris 456216 R-CFA-177934 https://reactome.org/PathwayBrowser/#/R-CFA-177934 EGFR autophosphorylation IEA Canis familiaris 456216 R-CFA-177937 https://reactome.org/PathwayBrowser/#/R-CFA-177937 Phosphorylation of EGFR by SRC kinase IEA Canis familiaris 456216 R-CFA-177939 https://reactome.org/PathwayBrowser/#/R-CFA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Canis familiaris 456216 R-CFA-182969 https://reactome.org/PathwayBrowser/#/R-CFA-182969 Phosphorylation of CBL (EGFR:CBL) IEA Canis familiaris 456216 R-CFA-183058 https://reactome.org/PathwayBrowser/#/R-CFA-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Canis familiaris 456216 R-CFA-1855153 https://reactome.org/PathwayBrowser/#/R-CFA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Canis familiaris 456216 R-CFA-1855157 https://reactome.org/PathwayBrowser/#/R-CFA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Canis familiaris 456216 R-CFA-1855158 https://reactome.org/PathwayBrowser/#/R-CFA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Canis familiaris 456216 R-CFA-1855162 https://reactome.org/PathwayBrowser/#/R-CFA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Canis familiaris 456216 R-CFA-1855169 https://reactome.org/PathwayBrowser/#/R-CFA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 456216 R-CFA-1855172 https://reactome.org/PathwayBrowser/#/R-CFA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Canis familiaris 456216 R-CFA-1855176 https://reactome.org/PathwayBrowser/#/R-CFA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Canis familiaris 456216 R-CFA-1855179 https://reactome.org/PathwayBrowser/#/R-CFA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Canis familiaris 456216 R-CFA-1855181 https://reactome.org/PathwayBrowser/#/R-CFA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Canis familiaris 456216 R-CFA-1855182 https://reactome.org/PathwayBrowser/#/R-CFA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Canis familiaris 456216 R-CFA-1855185 https://reactome.org/PathwayBrowser/#/R-CFA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 456216 R-CFA-1855193 https://reactome.org/PathwayBrowser/#/R-CFA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Canis familiaris 456216 R-CFA-1855194 https://reactome.org/PathwayBrowser/#/R-CFA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Canis familiaris 456216 R-CFA-1855197 https://reactome.org/PathwayBrowser/#/R-CFA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 456216 R-CFA-1855206 https://reactome.org/PathwayBrowser/#/R-CFA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 456216 R-CFA-1855207 https://reactome.org/PathwayBrowser/#/R-CFA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Canis familiaris 456216 R-CFA-1855216 https://reactome.org/PathwayBrowser/#/R-CFA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Canis familiaris 456216 R-CFA-1855223 https://reactome.org/PathwayBrowser/#/R-CFA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Canis familiaris 456216 R-CFA-1855224 https://reactome.org/PathwayBrowser/#/R-CFA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Canis familiaris 456216 R-CFA-1855227 https://reactome.org/PathwayBrowser/#/R-CFA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Canis familiaris 456216 R-CFA-1855228 https://reactome.org/PathwayBrowser/#/R-CFA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 456216 R-CFA-1855230 https://reactome.org/PathwayBrowser/#/R-CFA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Canis familiaris 456216 R-CFA-1855233 https://reactome.org/PathwayBrowser/#/R-CFA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Canis familiaris 456216 R-CFA-1861595 https://reactome.org/PathwayBrowser/#/R-CFA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Canis familiaris 456216 R-CFA-186786 https://reactome.org/PathwayBrowser/#/R-CFA-186786 Autophosphorylation of PDGF beta receptors IEA Canis familiaris 456216 R-CFA-186800 https://reactome.org/PathwayBrowser/#/R-CFA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-187520 https://reactome.org/PathwayBrowser/#/R-CFA-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Canis familiaris 456216 R-CFA-187916 https://reactome.org/PathwayBrowser/#/R-CFA-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Canis familiaris 456216 R-CFA-187948 https://reactome.org/PathwayBrowser/#/R-CFA-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Canis familiaris 456216 R-CFA-187949 https://reactome.org/PathwayBrowser/#/R-CFA-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Canis familiaris 456216 R-CFA-187959 https://reactome.org/PathwayBrowser/#/R-CFA-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Canis familiaris 456216 R-CFA-188350 https://reactome.org/PathwayBrowser/#/R-CFA-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Canis familiaris 456216 R-CFA-188390 https://reactome.org/PathwayBrowser/#/R-CFA-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Canis familiaris 456216 R-CFA-190326 https://reactome.org/PathwayBrowser/#/R-CFA-190326 Autocatalytic phosphorylation of FGFR4 IEA Canis familiaris 456216 R-CFA-190385 https://reactome.org/PathwayBrowser/#/R-CFA-190385 Autocatalytic phosphorylation of FGFR3b IEA Canis familiaris 456216 R-CFA-190388 https://reactome.org/PathwayBrowser/#/R-CFA-190388 Autocatalytic phosphorylation of FGFR3c IEA Canis familiaris 456216 R-CFA-190408 https://reactome.org/PathwayBrowser/#/R-CFA-190408 Autocatalytic phosphorylation of FGFR2b IEA Canis familiaris 456216 R-CFA-190413 https://reactome.org/PathwayBrowser/#/R-CFA-190413 Autocatalytic phosphorylation of FGFR2c IEA Canis familiaris 456216 R-CFA-190427 https://reactome.org/PathwayBrowser/#/R-CFA-190427 Autocatalytic phosphorylation of FGFR1b IEA Canis familiaris 456216 R-CFA-190429 https://reactome.org/PathwayBrowser/#/R-CFA-190429 Autocatalytic phosphorylation of FGFR1c IEA Canis familiaris 456216 R-CFA-191062 https://reactome.org/PathwayBrowser/#/R-CFA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Canis familiaris 456216 R-CFA-191380 https://reactome.org/PathwayBrowser/#/R-CFA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Canis familiaris 456216 R-CFA-191414 https://reactome.org/PathwayBrowser/#/R-CFA-191414 MVD decarboxylates MVA5PP to IPPP IEA Canis familiaris 456216 R-CFA-191422 https://reactome.org/PathwayBrowser/#/R-CFA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Canis familiaris 456216 R-CFA-191636 https://reactome.org/PathwayBrowser/#/R-CFA-191636 Phosphorylation of Cx43 by c-src IEA Canis familiaris 456216 R-CFA-193362 https://reactome.org/PathwayBrowser/#/R-CFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-193703 https://reactome.org/PathwayBrowser/#/R-CFA-193703 IKKbeta is activated IEA Canis familiaris 456216 R-CFA-193705 https://reactome.org/PathwayBrowser/#/R-CFA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Canis familiaris 456216 R-CFA-194153 https://reactome.org/PathwayBrowser/#/R-CFA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-195275 https://reactome.org/PathwayBrowser/#/R-CFA-195275 Phosphorylation of APC component of the destruction complex IEA Canis familiaris 456216 R-CFA-195283 https://reactome.org/PathwayBrowser/#/R-CFA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Canis familiaris 456216 R-CFA-195287 https://reactome.org/PathwayBrowser/#/R-CFA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Canis familiaris 456216 R-CFA-195300 https://reactome.org/PathwayBrowser/#/R-CFA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Canis familiaris 456216 R-CFA-195318 https://reactome.org/PathwayBrowser/#/R-CFA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Canis familiaris 456216 R-CFA-1963581 https://reactome.org/PathwayBrowser/#/R-CFA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Canis familiaris 456216 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 456216 R-CFA-1963586 https://reactome.org/PathwayBrowser/#/R-CFA-1963586 SRC family kinases phosphorylate ERBB2 IEA Canis familiaris 456216 R-CFA-196773 https://reactome.org/PathwayBrowser/#/R-CFA-196773 COASY phosphorylates DP-CoA IEA Canis familiaris 456216 R-CFA-196857 https://reactome.org/PathwayBrowser/#/R-CFA-196857 PANK2 phosphorylates PanK IEA Canis familiaris 456216 R-CFA-196964 https://reactome.org/PathwayBrowser/#/R-CFA-196964 RFK:Mg2+ phosphorylates RIB IEA Canis familiaris 456216 R-CFA-197198 https://reactome.org/PathwayBrowser/#/R-CFA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Canis familiaris 456216 R-CFA-197958 https://reactome.org/PathwayBrowser/#/R-CFA-197958 FPGS-2 transforms THF to THFPG IEA Canis familiaris 456216 R-CFA-198266 https://reactome.org/PathwayBrowser/#/R-CFA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Canis familiaris 456216 R-CFA-198314 https://reactome.org/PathwayBrowser/#/R-CFA-198314 DAG stimulates protein kinase C-delta IEA Canis familiaris 456216 R-CFA-198669 https://reactome.org/PathwayBrowser/#/R-CFA-198669 p38MAPK phosphorylates MSK1 IEA Canis familiaris 456216 R-CFA-198746 https://reactome.org/PathwayBrowser/#/R-CFA-198746 ERK1/2/5 activate RSK1/2/3 IEA Canis familiaris 456216 R-CFA-198756 https://reactome.org/PathwayBrowser/#/R-CFA-198756 ERK1/2 phosphorylates MSK1 IEA Canis familiaris 456216 R-CFA-199203 https://reactome.org/PathwayBrowser/#/R-CFA-199203 PANK1/3 phosphorylate PanK IEA Canis familiaris 456216 R-CFA-199895 https://reactome.org/PathwayBrowser/#/R-CFA-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Canis familiaris 456216 R-CFA-199910 https://reactome.org/PathwayBrowser/#/R-CFA-199910 MSK1 activates ATF1 IEA Canis familiaris 456216 R-CFA-199935 https://reactome.org/PathwayBrowser/#/R-CFA-199935 MSK1 activates CREB IEA Canis familiaris 456216 R-CFA-200318 https://reactome.org/PathwayBrowser/#/R-CFA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Canis familiaris 456216 R-CFA-200326 https://reactome.org/PathwayBrowser/#/R-CFA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Canis familiaris 456216 R-CFA-200421 https://reactome.org/PathwayBrowser/#/R-CFA-200421 Activation of cytosolic AMPK by phosphorylation IEA Canis familiaris 456216 R-CFA-200423 https://reactome.org/PathwayBrowser/#/R-CFA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Canis familiaris 456216 R-CFA-200555 https://reactome.org/PathwayBrowser/#/R-CFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Canis familiaris 456216 R-CFA-200681 https://reactome.org/PathwayBrowser/#/R-CFA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Canis familiaris 456216 R-CFA-200682 https://reactome.org/PathwayBrowser/#/R-CFA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Canis familiaris 456216 R-CFA-200711 https://reactome.org/PathwayBrowser/#/R-CFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Canis familiaris 456216 R-CFA-201443 https://reactome.org/PathwayBrowser/#/R-CFA-201443 Type II receptor phosphorylates type I receptor IEA Canis familiaris 456216 R-CFA-201476 https://reactome.org/PathwayBrowser/#/R-CFA-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Canis familiaris 456216 R-CFA-201510 https://reactome.org/PathwayBrowser/#/R-CFA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Canis familiaris 456216 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 456216 R-CFA-201677 https://reactome.org/PathwayBrowser/#/R-CFA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Canis familiaris 456216 R-CFA-201717 https://reactome.org/PathwayBrowser/#/R-CFA-201717 CSNK2-mediated phosphorylation of DVL IEA Canis familiaris 456216 R-CFA-202165 https://reactome.org/PathwayBrowser/#/R-CFA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Canis familiaris 456216 R-CFA-202168 https://reactome.org/PathwayBrowser/#/R-CFA-202168 Phosphorylation of ZAP-70 by Lck IEA Canis familiaris 456216 R-CFA-202174 https://reactome.org/PathwayBrowser/#/R-CFA-202174 Activation of ZAP-70 IEA Canis familiaris 456216 R-CFA-202216 https://reactome.org/PathwayBrowser/#/R-CFA-202216 Phosphorylation of SLP-76 IEA Canis familiaris 456216 R-CFA-202222 https://reactome.org/PathwayBrowser/#/R-CFA-202222 Phosphorylation of PKC theta IEA Canis familiaris 456216 R-CFA-202233 https://reactome.org/PathwayBrowser/#/R-CFA-202233 Inactivation of Lck by Csk IEA Canis familiaris 456216 R-CFA-202245 https://reactome.org/PathwayBrowser/#/R-CFA-202245 Phosphorylation of TBSMs in LAT IEA Canis familiaris 456216 R-CFA-202248 https://reactome.org/PathwayBrowser/#/R-CFA-202248 Phosphorylation of PLC-gamma1 IEA Canis familiaris 456216 R-CFA-202291 https://reactome.org/PathwayBrowser/#/R-CFA-202291 Activation of Lck IEA Canis familiaris 456216 R-CFA-202307 https://reactome.org/PathwayBrowser/#/R-CFA-202307 Change of PKC theta conformation IEA Canis familiaris 456216 R-CFA-202365 https://reactome.org/PathwayBrowser/#/R-CFA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-202437 https://reactome.org/PathwayBrowser/#/R-CFA-202437 Phosphorylation of CARMA1 IEA Canis familiaris 456216 R-CFA-202459 https://reactome.org/PathwayBrowser/#/R-CFA-202459 Phosphorylation of Bcl10 IEA Canis familiaris 456216 R-CFA-202500 https://reactome.org/PathwayBrowser/#/R-CFA-202500 Activation of IKK complex IEA Canis familiaris 456216 R-CFA-202510 https://reactome.org/PathwayBrowser/#/R-CFA-202510 Activation of TAK1-TAB2 complex IEA Canis familiaris 456216 R-CFA-202541 https://reactome.org/PathwayBrowser/#/R-CFA-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Canis familiaris 456216 R-CFA-2028284 https://reactome.org/PathwayBrowser/#/R-CFA-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Canis familiaris 456216 R-CFA-2028555 https://reactome.org/PathwayBrowser/#/R-CFA-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Canis familiaris 456216 R-CFA-2028583 https://reactome.org/PathwayBrowser/#/R-CFA-2028583 Phosphorylation of YAP by LATS2 IEA Canis familiaris 456216 R-CFA-2028589 https://reactome.org/PathwayBrowser/#/R-CFA-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Canis familiaris 456216 R-CFA-2028591 https://reactome.org/PathwayBrowser/#/R-CFA-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Canis familiaris 456216 R-CFA-2028598 https://reactome.org/PathwayBrowser/#/R-CFA-2028598 Phosphorylation of YAP by LATS1 IEA Canis familiaris 456216 R-CFA-2028629 https://reactome.org/PathwayBrowser/#/R-CFA-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Canis familiaris 456216 R-CFA-2028635 https://reactome.org/PathwayBrowser/#/R-CFA-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Canis familiaris 456216 R-CFA-2028661 https://reactome.org/PathwayBrowser/#/R-CFA-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Canis familiaris 456216 R-CFA-2028670 https://reactome.org/PathwayBrowser/#/R-CFA-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Canis familiaris 456216 R-CFA-2028673 https://reactome.org/PathwayBrowser/#/R-CFA-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Canis familiaris 456216 R-CFA-2028675 https://reactome.org/PathwayBrowser/#/R-CFA-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Canis familiaris 456216 R-CFA-2028679 https://reactome.org/PathwayBrowser/#/R-CFA-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Canis familiaris 456216 R-CFA-2029268 https://reactome.org/PathwayBrowser/#/R-CFA-2029268 Phosphorylation and activation of PLCG IEA Canis familiaris 456216 R-CFA-2029271 https://reactome.org/PathwayBrowser/#/R-CFA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-2029453 https://reactome.org/PathwayBrowser/#/R-CFA-2029453 Phosphorylation of VAV IEA Canis familiaris 456216 R-CFA-2029454 https://reactome.org/PathwayBrowser/#/R-CFA-2029454 Autophosphorylation of PAK1 IEA Canis familiaris 456216 R-CFA-2029459 https://reactome.org/PathwayBrowser/#/R-CFA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Canis familiaris 456216 R-CFA-2029460 https://reactome.org/PathwayBrowser/#/R-CFA-2029460 PAK1 phosphorylates LIMK1 IEA Canis familiaris 456216 R-CFA-2029469 https://reactome.org/PathwayBrowser/#/R-CFA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Canis familiaris 456216 R-CFA-2029473 https://reactome.org/PathwayBrowser/#/R-CFA-2029473 Branching and elongation of mother and daughter filaments IEA Canis familiaris 456216 R-CFA-2029476 https://reactome.org/PathwayBrowser/#/R-CFA-2029476 Role of myosins in phagosome formation IEA Canis familiaris 456216 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 456216 R-CFA-2046087 https://reactome.org/PathwayBrowser/#/R-CFA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Canis familiaris 456216 R-CFA-2046093 https://reactome.org/PathwayBrowser/#/R-CFA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Canis familiaris 456216 R-CFA-205075 https://reactome.org/PathwayBrowser/#/R-CFA-205075 JNK phosphorylates BIM, BAD and other targets IEA Canis familiaris 456216 R-CFA-205136 https://reactome.org/PathwayBrowser/#/R-CFA-205136 GTP-bound RAC contributes to JNK activation IEA Canis familiaris 456216 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 456216 R-CFA-2060328 https://reactome.org/PathwayBrowser/#/R-CFA-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Canis familiaris 456216 R-CFA-209087 https://reactome.org/PathwayBrowser/#/R-CFA-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Canis familiaris 456216 R-CFA-210291 https://reactome.org/PathwayBrowser/#/R-CFA-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Canis familiaris 456216 R-CFA-212710 https://reactome.org/PathwayBrowser/#/R-CFA-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Canis familiaris 456216 R-CFA-2130194 https://reactome.org/PathwayBrowser/#/R-CFA-2130194 ABL phosphorylates WAVEs IEA Canis familiaris 456216 R-CFA-216723 https://reactome.org/PathwayBrowser/#/R-CFA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Canis familiaris 456216 R-CFA-216757 https://reactome.org/PathwayBrowser/#/R-CFA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Canis familiaris 456216 R-CFA-2176475 https://reactome.org/PathwayBrowser/#/R-CFA-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Canis familiaris 456216 R-CFA-2197690 https://reactome.org/PathwayBrowser/#/R-CFA-2197690 Detachment of WASP/WAVE IEA Canis familiaris 456216 R-CFA-2197698 https://reactome.org/PathwayBrowser/#/R-CFA-2197698 Src phosphorylate WASP,N-WASP IEA Canis familiaris 456216 R-CFA-2213248 https://reactome.org/PathwayBrowser/#/R-CFA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Canis familiaris 456216 R-CFA-2214351 https://reactome.org/PathwayBrowser/#/R-CFA-2214351 PLK1 phosphorylates GORASP1 IEA Canis familiaris 456216 R-CFA-2267372 https://reactome.org/PathwayBrowser/#/R-CFA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Canis familiaris 456216 R-CFA-2294580 https://reactome.org/PathwayBrowser/#/R-CFA-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Canis familiaris 456216 R-CFA-2294600 https://reactome.org/PathwayBrowser/#/R-CFA-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Canis familiaris 456216 R-CFA-2316434 https://reactome.org/PathwayBrowser/#/R-CFA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-2395412 https://reactome.org/PathwayBrowser/#/R-CFA-2395412 Phosphorylation of SYK IEA Canis familiaris 456216 R-CFA-2395801 https://reactome.org/PathwayBrowser/#/R-CFA-2395801 Phosphorylation of LAT by p-SYK IEA Canis familiaris 456216 R-CFA-2396594 https://reactome.org/PathwayBrowser/#/R-CFA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Canis familiaris 456216 R-CFA-2404193 https://reactome.org/PathwayBrowser/#/R-CFA-2404193 IGF1R phosphorylates SHC1 IEA Canis familiaris 456216 R-CFA-2404199 https://reactome.org/PathwayBrowser/#/R-CFA-2404199 IGF1,2:IGF1R autophosphorylates IEA Canis familiaris 456216 R-CFA-2422927 https://reactome.org/PathwayBrowser/#/R-CFA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Canis familiaris 456216 R-CFA-2424480 https://reactome.org/PathwayBrowser/#/R-CFA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-2424484 https://reactome.org/PathwayBrowser/#/R-CFA-2424484 Phosphorylation of BTK by p-SYK IEA Canis familiaris 456216 R-CFA-2424486 https://reactome.org/PathwayBrowser/#/R-CFA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Canis familiaris 456216 R-CFA-2424487 https://reactome.org/PathwayBrowser/#/R-CFA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Canis familiaris 456216 R-CFA-2428926 https://reactome.org/PathwayBrowser/#/R-CFA-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Canis familiaris 456216 R-CFA-2430535 https://reactome.org/PathwayBrowser/#/R-CFA-2430535 MASTL phosphorylates ENSA IEA Canis familiaris 456216 R-CFA-2454208 https://reactome.org/PathwayBrowser/#/R-CFA-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Canis familiaris 456216 R-CFA-2466068 https://reactome.org/PathwayBrowser/#/R-CFA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Canis familiaris 456216 R-CFA-2468287 https://reactome.org/PathwayBrowser/#/R-CFA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Canis familiaris 456216 R-CFA-2468293 https://reactome.org/PathwayBrowser/#/R-CFA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Canis familiaris 456216 R-CFA-2529020 https://reactome.org/PathwayBrowser/#/R-CFA-2529020 CK2 phosphorylates condensin I subunits IEA Canis familiaris 456216 R-CFA-2562526 https://reactome.org/PathwayBrowser/#/R-CFA-2562526 PLK1 phosphorylates OPTN IEA Canis familiaris 456216 R-CFA-2574840 https://reactome.org/PathwayBrowser/#/R-CFA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Canis familiaris 456216 R-CFA-2581474 https://reactome.org/PathwayBrowser/#/R-CFA-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Canis familiaris 456216 R-CFA-265682 https://reactome.org/PathwayBrowser/#/R-CFA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Canis familiaris 456216 R-CFA-265783 https://reactome.org/PathwayBrowser/#/R-CFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-266082 https://reactome.org/PathwayBrowser/#/R-CFA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Canis familiaris 456216 R-CFA-2682349 https://reactome.org/PathwayBrowser/#/R-CFA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Canis familiaris 456216 R-CFA-2730833 https://reactome.org/PathwayBrowser/#/R-CFA-2730833 Phosphorylation of TEC kinases by p-SYK IEA Canis familiaris 456216 R-CFA-2730835 https://reactome.org/PathwayBrowser/#/R-CFA-2730835 Autophosphorylation of PKC-theta IEA Canis familiaris 456216 R-CFA-2730841 https://reactome.org/PathwayBrowser/#/R-CFA-2730841 Phosphorylation and activation of VAV IEA Canis familiaris 456216 R-CFA-2730843 https://reactome.org/PathwayBrowser/#/R-CFA-2730843 Phosphorylation of LAT by p-SYK IEA Canis familiaris 456216 R-CFA-2730851 https://reactome.org/PathwayBrowser/#/R-CFA-2730851 Phosphorylation of SLP-76 by p-SYK IEA Canis familiaris 456216 R-CFA-2730856 https://reactome.org/PathwayBrowser/#/R-CFA-2730856 Autophosphorylation of PAK IEA Canis familiaris 456216 R-CFA-2730858 https://reactome.org/PathwayBrowser/#/R-CFA-2730858 Autophosphorylation of BTK/ITK IEA Canis familiaris 456216 R-CFA-2730862 https://reactome.org/PathwayBrowser/#/R-CFA-2730862 Autophosphorylation of LYN kinase IEA Canis familiaris 456216 R-CFA-2730863 https://reactome.org/PathwayBrowser/#/R-CFA-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Canis familiaris 456216 R-CFA-2730868 https://reactome.org/PathwayBrowser/#/R-CFA-2730868 Phosphorylation of MEK7 by MEKK1 IEA Canis familiaris 456216 R-CFA-2730870 https://reactome.org/PathwayBrowser/#/R-CFA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Canis familiaris 456216 R-CFA-2730876 https://reactome.org/PathwayBrowser/#/R-CFA-2730876 Phosphorylation of IKK-beta by TAK1 IEA Canis familiaris 456216 R-CFA-2730882 https://reactome.org/PathwayBrowser/#/R-CFA-2730882 Phosphorylation of PKC-theta IEA Canis familiaris 456216 R-CFA-2730884 https://reactome.org/PathwayBrowser/#/R-CFA-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Canis familiaris 456216 R-CFA-2730886 https://reactome.org/PathwayBrowser/#/R-CFA-2730886 Phosphorylation of SHC by SYK kinase IEA Canis familiaris 456216 R-CFA-2730896 https://reactome.org/PathwayBrowser/#/R-CFA-2730896 Phosphorylation of MEK4 by MEKK1 IEA Canis familiaris 456216 R-CFA-2730900 https://reactome.org/PathwayBrowser/#/R-CFA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Canis familiaris 456216 R-CFA-2984220 https://reactome.org/PathwayBrowser/#/R-CFA-2984220 CDK1:CCNB phosphorylates NEK9 IEA Canis familiaris 456216 R-CFA-2984226 https://reactome.org/PathwayBrowser/#/R-CFA-2984226 PLK1 phosphorylates NEK9 IEA Canis familiaris 456216 R-CFA-2984258 https://reactome.org/PathwayBrowser/#/R-CFA-2984258 NEK9 phosphorylates NEK6/NEK7 IEA Canis familiaris 456216 R-CFA-2990880 https://reactome.org/PathwayBrowser/#/R-CFA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Canis familiaris 456216 R-CFA-2990882 https://reactome.org/PathwayBrowser/#/R-CFA-2990882 CDK1 phosphorylates NUP98 IEA Canis familiaris 456216 R-CFA-2993898 https://reactome.org/PathwayBrowser/#/R-CFA-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Canis familiaris 456216 R-CFA-3000310 https://reactome.org/PathwayBrowser/#/R-CFA-3000310 AURKA phosphorylates PLK1 IEA Canis familiaris 456216 R-CFA-3000327 https://reactome.org/PathwayBrowser/#/R-CFA-3000327 PLK1 phosphorylates BORA IEA Canis familiaris 456216 R-CFA-3095901 https://reactome.org/PathwayBrowser/#/R-CFA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Canis familiaris 456216 R-CFA-3132737 https://reactome.org/PathwayBrowser/#/R-CFA-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Canis familiaris 456216 R-CFA-3222006 https://reactome.org/PathwayBrowser/#/R-CFA-3222006 STK11 (LKB1) phosphorylates NUAK1 IEA Canis familiaris 456216 R-CFA-3222020 https://reactome.org/PathwayBrowser/#/R-CFA-3222020 NUAK1 phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-3228469 https://reactome.org/PathwayBrowser/#/R-CFA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Canis familiaris 456216 R-CFA-3249379 https://reactome.org/PathwayBrowser/#/R-CFA-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Canis familiaris 456216 R-CFA-3371422 https://reactome.org/PathwayBrowser/#/R-CFA-3371422 ATP hydrolysis by HSP70 IEA Canis familiaris 456216 R-CFA-3371435 https://reactome.org/PathwayBrowser/#/R-CFA-3371435 Constitutive phosphorylation by GSK3 IEA Canis familiaris 456216 R-CFA-3371503 https://reactome.org/PathwayBrowser/#/R-CFA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Canis familiaris 456216 R-CFA-3371531 https://reactome.org/PathwayBrowser/#/R-CFA-3371531 Constitutive phosphorylation by pERK1/2 IEA Canis familiaris 456216 R-CFA-349426 https://reactome.org/PathwayBrowser/#/R-CFA-349426 Phosphorylation of MDM4 by CHEK2 IEA Canis familiaris 456216 R-CFA-349444 https://reactome.org/PathwayBrowser/#/R-CFA-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Canis familiaris 456216 R-CFA-349455 https://reactome.org/PathwayBrowser/#/R-CFA-349455 Phosphorylation of MDM4 by ATM IEA Canis familiaris 456216 R-CFA-354073 https://reactome.org/PathwayBrowser/#/R-CFA-354073 Autophosphorylation of PTK2 at Y397 IEA Canis familiaris 456216 R-CFA-354124 https://reactome.org/PathwayBrowser/#/R-CFA-354124 Phosphorylation of pPTK2 by SRC IEA Canis familiaris 456216 R-CFA-372693 https://reactome.org/PathwayBrowser/#/R-CFA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Canis familiaris 456216 R-CFA-373747 https://reactome.org/PathwayBrowser/#/R-CFA-373747 Phosphorylation of nephrin by FYN IEA Canis familiaris 456216 R-CFA-373750 https://reactome.org/PathwayBrowser/#/R-CFA-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Canis familiaris 456216 R-CFA-374664 https://reactome.org/PathwayBrowser/#/R-CFA-374664 Phosphorylation and activation of Ezrin IEA Canis familiaris 456216 R-CFA-374701 https://reactome.org/PathwayBrowser/#/R-CFA-374701 Phosphorylation of DCC by Fyn IEA Canis familiaris 456216 R-CFA-3772436 https://reactome.org/PathwayBrowser/#/R-CFA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Canis familiaris 456216 R-CFA-377640 https://reactome.org/PathwayBrowser/#/R-CFA-377640 Autophosphorylation of SRC IEA Canis familiaris 456216 R-CFA-3788705 https://reactome.org/PathwayBrowser/#/R-CFA-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Canis familiaris 456216 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 456216 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 456216 R-CFA-380272 https://reactome.org/PathwayBrowser/#/R-CFA-380272 Plk1-mediated phosphorylation of Nlp IEA Canis familiaris 456216 R-CFA-380278 https://reactome.org/PathwayBrowser/#/R-CFA-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Canis familiaris 456216 R-CFA-380780 https://reactome.org/PathwayBrowser/#/R-CFA-380780 Activation of Src IEA Canis familiaris 456216 R-CFA-380927 https://reactome.org/PathwayBrowser/#/R-CFA-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Canis familiaris 456216 R-CFA-381091 https://reactome.org/PathwayBrowser/#/R-CFA-381091 IRE1 dimer autophosphorylates IEA Canis familiaris 456216 R-CFA-381111 https://reactome.org/PathwayBrowser/#/R-CFA-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Canis familiaris 456216 R-CFA-382553 https://reactome.org/PathwayBrowser/#/R-CFA-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Canis familiaris 456216 R-CFA-382560 https://reactome.org/PathwayBrowser/#/R-CFA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Canis familiaris 456216 R-CFA-382575 https://reactome.org/PathwayBrowser/#/R-CFA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Canis familiaris 456216 R-CFA-383190 https://reactome.org/PathwayBrowser/#/R-CFA-383190 HCO3- transport through ion channel IEA Canis familiaris 456216 R-CFA-3857329 https://reactome.org/PathwayBrowser/#/R-CFA-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Canis familiaris 456216 R-CFA-388831 https://reactome.org/PathwayBrowser/#/R-CFA-388831 Phosphorylation of CD28 IEA Canis familiaris 456216 R-CFA-388833 https://reactome.org/PathwayBrowser/#/R-CFA-388833 Phosphorylation of CTLA-4 IEA Canis familiaris 456216 R-CFA-389083 https://reactome.org/PathwayBrowser/#/R-CFA-389083 Autophosphorylation of PDGF alpha receptors IEA Canis familiaris 456216 R-CFA-389086 https://reactome.org/PathwayBrowser/#/R-CFA-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Canis familiaris 456216 R-CFA-389158 https://reactome.org/PathwayBrowser/#/R-CFA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-389354 https://reactome.org/PathwayBrowser/#/R-CFA-389354 Activation of Vav1 IEA Canis familiaris 456216 R-CFA-389762 https://reactome.org/PathwayBrowser/#/R-CFA-389762 Phosphorylation of PD-1 IEA Canis familiaris 456216 R-CFA-390593 https://reactome.org/PathwayBrowser/#/R-CFA-390593 ATP Hydrolysis By Myosin IEA Canis familiaris 456216 R-CFA-390597 https://reactome.org/PathwayBrowser/#/R-CFA-390597 Release Of ADP From Myosin IEA Canis familiaris 456216 R-CFA-391266 https://reactome.org/PathwayBrowser/#/R-CFA-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Canis familiaris 456216 R-CFA-392187 https://reactome.org/PathwayBrowser/#/R-CFA-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Canis familiaris 456216 R-CFA-392195 https://reactome.org/PathwayBrowser/#/R-CFA-392195 Gi activation by P2Y purinoceptor 12 IEA Canis familiaris 456216 R-CFA-392202 https://reactome.org/PathwayBrowser/#/R-CFA-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Canis familiaris 456216 R-CFA-392300 https://reactome.org/PathwayBrowser/#/R-CFA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-392530 https://reactome.org/PathwayBrowser/#/R-CFA-392530 p-S400-Cot phosphorylates NIK IEA Canis familiaris 456216 R-CFA-3928578 https://reactome.org/PathwayBrowser/#/R-CFA-3928578 EPH receptors autophosphorylate IEA Canis familiaris 456216 R-CFA-3928604 https://reactome.org/PathwayBrowser/#/R-CFA-3928604 SFKs phosphorylate VAV2,3 IEA Canis familiaris 456216 R-CFA-3928620 https://reactome.org/PathwayBrowser/#/R-CFA-3928620 PAK1 autophosphorylates IEA Canis familiaris 456216 R-CFA-3928625 https://reactome.org/PathwayBrowser/#/R-CFA-3928625 PAKs autophosphorylate IEA Canis familiaris 456216 R-CFA-3928627 https://reactome.org/PathwayBrowser/#/R-CFA-3928627 EPHB phosphorylates TIAM1 IEA Canis familiaris 456216 R-CFA-3928640 https://reactome.org/PathwayBrowser/#/R-CFA-3928640 PAKs phosphorylate MLC IEA Canis familiaris 456216 R-CFA-399939 https://reactome.org/PathwayBrowser/#/R-CFA-399939 Autophosphorylation of PAK IEA Canis familiaris 456216 R-CFA-399944 https://reactome.org/PathwayBrowser/#/R-CFA-399944 Phosphorylation of CRMPs by Cdk5 IEA Canis familiaris 456216 R-CFA-399947 https://reactome.org/PathwayBrowser/#/R-CFA-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Canis familiaris 456216 R-CFA-399951 https://reactome.org/PathwayBrowser/#/R-CFA-399951 Phosphorylation of CRMPs by GSK3beta IEA Canis familiaris 456216 R-CFA-399952 https://reactome.org/PathwayBrowser/#/R-CFA-399952 Phosphorylation of LIMK-1 by PAK IEA Canis familiaris 456216 R-CFA-399978 https://reactome.org/PathwayBrowser/#/R-CFA-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Canis familiaris 456216 R-CFA-4085028 https://reactome.org/PathwayBrowser/#/R-CFA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Canis familiaris 456216 R-CFA-4086410 https://reactome.org/PathwayBrowser/#/R-CFA-4086410 CDK1 phosphorylates BORA IEA Canis familiaris 456216 R-CFA-4088024 https://reactome.org/PathwayBrowser/#/R-CFA-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Canis familiaris 456216 R-CFA-4088134 https://reactome.org/PathwayBrowser/#/R-CFA-4088134 PLK1 phosphorylates FOXM1 IEA Canis familiaris 456216 R-CFA-416320 https://reactome.org/PathwayBrowser/#/R-CFA-416320 Trafficking of GluR1-containing AMPA receptors IEA Canis familiaris 456216 R-CFA-416639 https://reactome.org/PathwayBrowser/#/R-CFA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Canis familiaris 456216 R-CFA-416985 https://reactome.org/PathwayBrowser/#/R-CFA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Canis familiaris 456216 R-CFA-417829 https://reactome.org/PathwayBrowser/#/R-CFA-417829 P2RY12 binds ADP IEA Canis familiaris 456216 R-CFA-417908 https://reactome.org/PathwayBrowser/#/R-CFA-417908 P2RY1 binds ADP IEA Canis familiaris 456216 R-CFA-418576 https://reactome.org/PathwayBrowser/#/R-CFA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Canis familiaris 456216 R-CFA-418845 https://reactome.org/PathwayBrowser/#/R-CFA-418845 Activation of caspase-3 IEA Canis familiaris 456216 R-CFA-419644 https://reactome.org/PathwayBrowser/#/R-CFA-419644 Transphosphorylation of pLIMK1 IEA Canis familiaris 456216 R-CFA-419646 https://reactome.org/PathwayBrowser/#/R-CFA-419646 SEMA4D interacts with Plexin-B1:Met IEA Canis familiaris 456216 R-CFA-421007 https://reactome.org/PathwayBrowser/#/R-CFA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Canis familiaris 456216 R-CFA-421836 https://reactome.org/PathwayBrowser/#/R-CFA-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Canis familiaris 456216 R-CFA-426240 https://reactome.org/PathwayBrowser/#/R-CFA-426240 DAG kinase produces phosphatidic acid from DAG IEA Canis familiaris 456216 R-CFA-428273 https://reactome.org/PathwayBrowser/#/R-CFA-428273 SPHK1 phosphorylates sphingoid IEA Canis familiaris 456216 R-CFA-428941 https://reactome.org/PathwayBrowser/#/R-CFA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Canis familiaris 456216 R-CFA-428961 https://reactome.org/PathwayBrowser/#/R-CFA-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Canis familiaris 456216 R-CFA-429157 https://reactome.org/PathwayBrowser/#/R-CFA-429157 ABCC4 accumulation of dense granule contents IEA Canis familiaris 456216 R-CFA-429441 https://reactome.org/PathwayBrowser/#/R-CFA-429441 SYK activation by SRC IEA Canis familiaris 456216 R-CFA-429449 https://reactome.org/PathwayBrowser/#/R-CFA-429449 Syk activation leads to SLP-76 activation IEA Canis familiaris 456216 R-CFA-432129 https://reactome.org/PathwayBrowser/#/R-CFA-432129 FGR binds and phosphorylates LRP8 IEA Canis familiaris 456216 R-CFA-432148 https://reactome.org/PathwayBrowser/#/R-CFA-432148 Fgr may phosphorylate p38 MAPK IEA Canis familiaris 456216 R-CFA-432232 https://reactome.org/PathwayBrowser/#/R-CFA-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Canis familiaris 456216 R-CFA-432688 https://reactome.org/PathwayBrowser/#/R-CFA-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating IEA Canis familiaris 456216 R-CFA-4332358 https://reactome.org/PathwayBrowser/#/R-CFA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Canis familiaris 456216 R-CFA-4332363 https://reactome.org/PathwayBrowser/#/R-CFA-4332363 Autophosphorylation and activation of CAMK2 IEA Canis familiaris 456216 R-CFA-434836 https://reactome.org/PathwayBrowser/#/R-CFA-434836 Syk/Lck phosphorylate LAT IEA Canis familiaris 456216 R-CFA-435244 https://reactome.org/PathwayBrowser/#/R-CFA-435244 PECAM1 is phosphorylated IEA Canis familiaris 456216 R-CFA-437162 https://reactome.org/PathwayBrowser/#/R-CFA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-4411383 https://reactome.org/PathwayBrowser/#/R-CFA-4411383 NLK phosphorylates TCF/LEF IEA Canis familiaris 456216 R-CFA-4411402 https://reactome.org/PathwayBrowser/#/R-CFA-4411402 Activation of NLK IEA Canis familiaris 456216 R-CFA-4420117 https://reactome.org/PathwayBrowser/#/R-CFA-4420117 VEGFR2 autophosphorylates IEA Canis familiaris 456216 R-CFA-4420121 https://reactome.org/PathwayBrowser/#/R-CFA-4420121 SFKs phosphorylate PLCG1 IEA Canis familiaris 456216 R-CFA-4420128 https://reactome.org/PathwayBrowser/#/R-CFA-4420128 SRC-1 phosphorylates SHB IEA Canis familiaris 456216 R-CFA-4420206 https://reactome.org/PathwayBrowser/#/R-CFA-4420206 Phosphorylation of SRC-1 IEA Canis familiaris 456216 R-CFA-442724 https://reactome.org/PathwayBrowser/#/R-CFA-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Canis familiaris 456216 R-CFA-442749 https://reactome.org/PathwayBrowser/#/R-CFA-442749 CaMKK autophosphorylates in the nucleus IEA Canis familiaris 456216 R-CFA-445072 https://reactome.org/PathwayBrowser/#/R-CFA-445072 Interaction of PAK1 with Rac1-GTP IEA Canis familiaris 456216 R-CFA-445079 https://reactome.org/PathwayBrowser/#/R-CFA-445079 Phosphorylation of L1 by ERK IEA Canis familiaris 456216 R-CFA-445699 https://reactome.org/PathwayBrowser/#/R-CFA-445699 ATP Hydrolysis By Myosin IEA Canis familiaris 456216 R-CFA-445705 https://reactome.org/PathwayBrowser/#/R-CFA-445705 Release Of ADP From Myosin IEA Canis familiaris 456216 R-CFA-445813 https://reactome.org/PathwayBrowser/#/R-CFA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Canis familiaris 456216 R-CFA-446634 https://reactome.org/PathwayBrowser/#/R-CFA-446634 IRAK4 is activated by autophosphorylation IEA Canis familiaris 456216 R-CFA-446694 https://reactome.org/PathwayBrowser/#/R-CFA-446694 IRAK4 phosphorylates IRAK1 IEA Canis familiaris 456216 R-CFA-446701 https://reactome.org/PathwayBrowser/#/R-CFA-446701 IRAK4-activated IRAK1 autophosphorylates IEA Canis familiaris 456216 R-CFA-447074 https://reactome.org/PathwayBrowser/#/R-CFA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Canis familiaris 456216 R-CFA-448955 https://reactome.org/PathwayBrowser/#/R-CFA-448955 Phosphorylation of MEF2 proteins by p38 IEA Canis familiaris 456216 R-CFA-450325 https://reactome.org/PathwayBrowser/#/R-CFA-450325 c-FOS activation by phospho ERK1/2 IEA Canis familiaris 456216 R-CFA-450337 https://reactome.org/PathwayBrowser/#/R-CFA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Canis familiaris 456216 R-CFA-450346 https://reactome.org/PathwayBrowser/#/R-CFA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Canis familiaris 456216 R-CFA-450533 https://reactome.org/PathwayBrowser/#/R-CFA-450533 PKCdelta phosphorylates HuR IEA Canis familiaris 456216 R-CFA-450550 https://reactome.org/PathwayBrowser/#/R-CFA-450550 PKCalpha phosphorylates HuR IEA Canis familiaris 456216 R-CFA-450827 https://reactome.org/PathwayBrowser/#/R-CFA-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Canis familiaris 456216 R-CFA-451942 https://reactome.org/PathwayBrowser/#/R-CFA-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Canis familiaris 456216 R-CFA-452097 https://reactome.org/PathwayBrowser/#/R-CFA-452097 Recruited STAT5 is phosphorylated IEA Canis familiaris 456216 R-CFA-452100 https://reactome.org/PathwayBrowser/#/R-CFA-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Canis familiaris 456216 R-CFA-452122 https://reactome.org/PathwayBrowser/#/R-CFA-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Canis familiaris 456216 R-CFA-453200 https://reactome.org/PathwayBrowser/#/R-CFA-453200 SYK autophosphorylates IEA Canis familiaris 456216 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 456216 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 456216 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 456216 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 456216 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 456216 R-CFA-504054 https://reactome.org/PathwayBrowser/#/R-CFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Canis familiaris 456216 R-CFA-508040 https://reactome.org/PathwayBrowser/#/R-CFA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Canis familiaris 456216 R-CFA-5082387 https://reactome.org/PathwayBrowser/#/R-CFA-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Canis familiaris 456216 R-CFA-5082405 https://reactome.org/PathwayBrowser/#/R-CFA-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Canis familiaris 456216 R-CFA-508282 https://reactome.org/PathwayBrowser/#/R-CFA-508282 SYK is a substrate for JAK1 IEA Canis familiaris 456216 R-CFA-508308 https://reactome.org/PathwayBrowser/#/R-CFA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Canis familiaris 456216 R-CFA-5138432 https://reactome.org/PathwayBrowser/#/R-CFA-5138432 DVL2 is phosphorylated by PKC IEA Canis familiaris 456216 R-CFA-5195402 https://reactome.org/PathwayBrowser/#/R-CFA-5195402 CDK1 phosphorylates LPIN IEA Canis familiaris 456216 R-CFA-5213464 https://reactome.org/PathwayBrowser/#/R-CFA-5213464 RIPK1 is phosphorylated IEA Canis familiaris 456216 R-CFA-5213466 https://reactome.org/PathwayBrowser/#/R-CFA-5213466 RIPK3 is phosphorylated IEA Canis familiaris 456216 R-CFA-5218640 https://reactome.org/PathwayBrowser/#/R-CFA-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Canis familiaris 456216 R-CFA-5218642 https://reactome.org/PathwayBrowser/#/R-CFA-5218642 PTK2 autophosphorylates IEA Canis familiaris 456216 R-CFA-5218804 https://reactome.org/PathwayBrowser/#/R-CFA-5218804 p38 MAPK activation by VEGFR IEA Canis familiaris 456216 R-CFA-5218805 https://reactome.org/PathwayBrowser/#/R-CFA-5218805 PKC autophosphorylates IEA Canis familiaris 456216 R-CFA-5218806 https://reactome.org/PathwayBrowser/#/R-CFA-5218806 FYN autophosphorylates IEA Canis familiaris 456216 R-CFA-5218809 https://reactome.org/PathwayBrowser/#/R-CFA-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Canis familiaris 456216 R-CFA-5218812 https://reactome.org/PathwayBrowser/#/R-CFA-5218812 FYN phosphorylates PAK2 IEA Canis familiaris 456216 R-CFA-5218814 https://reactome.org/PathwayBrowser/#/R-CFA-5218814 PAK2 autophorylates IEA Canis familiaris 456216 R-CFA-5218819 https://reactome.org/PathwayBrowser/#/R-CFA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-5218820 https://reactome.org/PathwayBrowser/#/R-CFA-5218820 Src kinases phosphorylate VAV IEA Canis familiaris 456216 R-CFA-5218821 https://reactome.org/PathwayBrowser/#/R-CFA-5218821 PDK1 phosphorylates PKC IEA Canis familiaris 456216 R-CFA-5218823 https://reactome.org/PathwayBrowser/#/R-CFA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Canis familiaris 456216 R-CFA-5218826 https://reactome.org/PathwayBrowser/#/R-CFA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Canis familiaris 456216 R-CFA-5218830 https://reactome.org/PathwayBrowser/#/R-CFA-5218830 SRC-1 phosphorylates PTK2-beta IEA Canis familiaris 456216 R-CFA-5218845 https://reactome.org/PathwayBrowser/#/R-CFA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Canis familiaris 456216 R-CFA-5218851 https://reactome.org/PathwayBrowser/#/R-CFA-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Canis familiaris 456216 R-CFA-5218854 https://reactome.org/PathwayBrowser/#/R-CFA-5218854 p-Y420-FYN is phosphorylated on S21 IEA Canis familiaris 456216 R-CFA-5223313 https://reactome.org/PathwayBrowser/#/R-CFA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Canis familiaris 456216 R-CFA-5223317 https://reactome.org/PathwayBrowser/#/R-CFA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Canis familiaris 456216 R-CFA-5229194 https://reactome.org/PathwayBrowser/#/R-CFA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Canis familiaris 456216 R-CFA-5229343 https://reactome.org/PathwayBrowser/#/R-CFA-5229343 AXIN is phosphorylated in the destruction complex IEA Canis familiaris 456216 R-CFA-5244669 https://reactome.org/PathwayBrowser/#/R-CFA-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Canis familiaris 456216 R-CFA-5251955 https://reactome.org/PathwayBrowser/#/R-CFA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Canis familiaris 456216 R-CFA-5251959 https://reactome.org/PathwayBrowser/#/R-CFA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Canis familiaris 456216 R-CFA-5251989 https://reactome.org/PathwayBrowser/#/R-CFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Canis familiaris 456216 R-CFA-5252079 https://reactome.org/PathwayBrowser/#/R-CFA-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Canis familiaris 456216 R-CFA-5357429 https://reactome.org/PathwayBrowser/#/R-CFA-5357429 AXL autophosphorylates on Y779 and Y821 IEA Canis familiaris 456216 R-CFA-5357472 https://reactome.org/PathwayBrowser/#/R-CFA-5357472 PAK1-3 autophosphorylates IEA Canis familiaris 456216 R-CFA-5357477 https://reactome.org/PathwayBrowser/#/R-CFA-5357477 PAK1-3 phosphorylates VE-cadherin IEA Canis familiaris 456216 R-CFA-5357831 https://reactome.org/PathwayBrowser/#/R-CFA-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Canis familiaris 456216 R-CFA-5358513 https://reactome.org/PathwayBrowser/#/R-CFA-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Canis familiaris 456216 R-CFA-5358525 https://reactome.org/PathwayBrowser/#/R-CFA-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Canis familiaris 456216 R-CFA-5358912 https://reactome.org/PathwayBrowser/#/R-CFA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Canis familiaris 456216 R-CFA-5362459 https://reactome.org/PathwayBrowser/#/R-CFA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Canis familiaris 456216 R-CFA-5444511 https://reactome.org/PathwayBrowser/#/R-CFA-5444511 Formation of MSH2:MSH3 Complex IEA Canis familiaris 456216 R-CFA-5444516 https://reactome.org/PathwayBrowser/#/R-CFA-5444516 Formation of MSH2:MSH6 Complex IEA Canis familiaris 456216 R-CFA-5607722 https://reactome.org/PathwayBrowser/#/R-CFA-5607722 Active NIK phosphorylates IKKA dimer IEA Canis familiaris 456216 R-CFA-5607726 https://reactome.org/PathwayBrowser/#/R-CFA-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Canis familiaris 456216 R-CFA-5607732 https://reactome.org/PathwayBrowser/#/R-CFA-5607732 K63polyUb-TAK1 autophosphorylates IEA Canis familiaris 456216 R-CFA-5607740 https://reactome.org/PathwayBrowser/#/R-CFA-5607740 PKC-delta phosphorylates CARD9 IEA Canis familiaris 456216 R-CFA-5607742 https://reactome.org/PathwayBrowser/#/R-CFA-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Canis familiaris 456216 R-CFA-5607750 https://reactome.org/PathwayBrowser/#/R-CFA-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Canis familiaris 456216 R-CFA-5610720 https://reactome.org/PathwayBrowser/#/R-CFA-5610720 PKA phosphorylates GLI3 IEA Canis familiaris 456216 R-CFA-5610722 https://reactome.org/PathwayBrowser/#/R-CFA-5610722 CK1 phosphorylates p-GLI3 IEA Canis familiaris 456216 R-CFA-5610732 https://reactome.org/PathwayBrowser/#/R-CFA-5610732 GSK3 phosphorylates p-GLI3 IEA Canis familiaris 456216 R-CFA-5617179 https://reactome.org/PathwayBrowser/#/R-CFA-5617179 PRKACA phosphorylates TNNI3 IEA Canis familiaris 456216 R-CFA-5617182 https://reactome.org/PathwayBrowser/#/R-CFA-5617182 PRKACA phosphorylates PLN IEA Canis familiaris 456216 R-CFA-5618085 https://reactome.org/PathwayBrowser/#/R-CFA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Canis familiaris 456216 R-CFA-5618107 https://reactome.org/PathwayBrowser/#/R-CFA-5618107 ATP binding to HSP90 triggers conformation change IEA Canis familiaris 456216 R-CFA-5621355 https://reactome.org/PathwayBrowser/#/R-CFA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Canis familiaris 456216 R-CFA-5621363 https://reactome.org/PathwayBrowser/#/R-CFA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Canis familiaris 456216 R-CFA-5621370 https://reactome.org/PathwayBrowser/#/R-CFA-5621370 SYK autophosphorylates IEA Canis familiaris 456216 R-CFA-5623667 https://reactome.org/PathwayBrowser/#/R-CFA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Canis familiaris 456216 R-CFA-5624473 https://reactome.org/PathwayBrowser/#/R-CFA-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Canis familiaris 456216 R-CFA-5624486 https://reactome.org/PathwayBrowser/#/R-CFA-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Canis familiaris 456216 R-CFA-5624492 https://reactome.org/PathwayBrowser/#/R-CFA-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Canis familiaris 456216 R-CFA-5625784 https://reactome.org/PathwayBrowser/#/R-CFA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Canis familiaris 456216 R-CFA-5627775 https://reactome.org/PathwayBrowser/#/R-CFA-5627775 Autophosphorylation of PAK1,2,3 IEA Canis familiaris 456216 R-CFA-5635842 https://reactome.org/PathwayBrowser/#/R-CFA-5635842 ULK3 phosphorylates GLI IEA Canis familiaris 456216 R-CFA-5654147 https://reactome.org/PathwayBrowser/#/R-CFA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Canis familiaris 456216 R-CFA-5654149 https://reactome.org/PathwayBrowser/#/R-CFA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Canis familiaris 456216 R-CFA-5654151 https://reactome.org/PathwayBrowser/#/R-CFA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Canis familiaris 456216 R-CFA-5654222 https://reactome.org/PathwayBrowser/#/R-CFA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Canis familiaris 456216 R-CFA-5654397 https://reactome.org/PathwayBrowser/#/R-CFA-5654397 Activated FGFR2 phosphorylates FRS2 IEA Canis familiaris 456216 R-CFA-5654407 https://reactome.org/PathwayBrowser/#/R-CFA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Canis familiaris 456216 R-CFA-5654408 https://reactome.org/PathwayBrowser/#/R-CFA-5654408 Activated FGFR3 phosphorylates FRS2 IEA Canis familiaris 456216 R-CFA-5654418 https://reactome.org/PathwayBrowser/#/R-CFA-5654418 Activated FGFR4 phosphorylates FRS2 IEA Canis familiaris 456216 R-CFA-5654428 https://reactome.org/PathwayBrowser/#/R-CFA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Canis familiaris 456216 R-CFA-5654560 https://reactome.org/PathwayBrowser/#/R-CFA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Canis familiaris 456216 R-CFA-5654562 https://reactome.org/PathwayBrowser/#/R-CFA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Canis familiaris 456216 R-CFA-5654565 https://reactome.org/PathwayBrowser/#/R-CFA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Canis familiaris 456216 R-CFA-5654566 https://reactome.org/PathwayBrowser/#/R-CFA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Canis familiaris 456216 R-CFA-5654575 https://reactome.org/PathwayBrowser/#/R-CFA-5654575 Activated FGFR1 phosphorylates FRS2 IEA Canis familiaris 456216 R-CFA-5654578 https://reactome.org/PathwayBrowser/#/R-CFA-5654578 Activated FGFR1 phosphorylates FRS3 IEA Canis familiaris 456216 R-CFA-5654582 https://reactome.org/PathwayBrowser/#/R-CFA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Canis familiaris 456216 R-CFA-5654587 https://reactome.org/PathwayBrowser/#/R-CFA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Canis familiaris 456216 R-CFA-5654605 https://reactome.org/PathwayBrowser/#/R-CFA-5654605 Activated FGFR2 phosphorylates FRS3 IEA Canis familiaris 456216 R-CFA-5654607 https://reactome.org/PathwayBrowser/#/R-CFA-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Canis familiaris 456216 R-CFA-5654628 https://reactome.org/PathwayBrowser/#/R-CFA-5654628 Activated FGFR3 phosphorylates FRS3 IEA Canis familiaris 456216 R-CFA-5654631 https://reactome.org/PathwayBrowser/#/R-CFA-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Canis familiaris 456216 R-CFA-5654634 https://reactome.org/PathwayBrowser/#/R-CFA-5654634 Activated FGFR3 phosphorylates SHC1 IEA Canis familiaris 456216 R-CFA-5654653 https://reactome.org/PathwayBrowser/#/R-CFA-5654653 Activated FGFR4 phosphorylates FRS3 IEA Canis familiaris 456216 R-CFA-5654655 https://reactome.org/PathwayBrowser/#/R-CFA-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Canis familiaris 456216 R-CFA-5654690 https://reactome.org/PathwayBrowser/#/R-CFA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-5654692 https://reactome.org/PathwayBrowser/#/R-CFA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-5654697 https://reactome.org/PathwayBrowser/#/R-CFA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-5654701 https://reactome.org/PathwayBrowser/#/R-CFA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-5654705 https://reactome.org/PathwayBrowser/#/R-CFA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-5654709 https://reactome.org/PathwayBrowser/#/R-CFA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-5654714 https://reactome.org/PathwayBrowser/#/R-CFA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-5654717 https://reactome.org/PathwayBrowser/#/R-CFA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-5654989 https://reactome.org/PathwayBrowser/#/R-CFA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Canis familiaris 456216 R-CFA-5662466 https://reactome.org/PathwayBrowser/#/R-CFA-5662466 XYLB phosphorylates D-xylulose IEA Canis familiaris 456216 R-CFA-5665868 https://reactome.org/PathwayBrowser/#/R-CFA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Canis familiaris 456216 R-CFA-5666160 https://reactome.org/PathwayBrowser/#/R-CFA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Canis familiaris 456216 R-CFA-5668545 https://reactome.org/PathwayBrowser/#/R-CFA-5668545 NIK autophosphorylates on T559 IEA Canis familiaris 456216 R-CFA-5668947 https://reactome.org/PathwayBrowser/#/R-CFA-5668947 PAK1 phosphorylates myosin phosphatase IEA Canis familiaris 456216 R-CFA-5668984 https://reactome.org/PathwayBrowser/#/R-CFA-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Canis familiaris 456216 R-CFA-5669250 https://reactome.org/PathwayBrowser/#/R-CFA-5669250 PAK1 phosphorylates FLNA IEA Canis familiaris 456216 R-CFA-5671749 https://reactome.org/PathwayBrowser/#/R-CFA-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Canis familiaris 456216 R-CFA-5671763 https://reactome.org/PathwayBrowser/#/R-CFA-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Canis familiaris 456216 R-CFA-5672008 https://reactome.org/PathwayBrowser/#/R-CFA-5672008 Thr-180 of ULK1 is phosphorylated IEA Canis familiaris 456216 R-CFA-5672010 https://reactome.org/PathwayBrowser/#/R-CFA-5672010 Active MTORC1 phosphorylates ULK1 IEA Canis familiaris 456216 R-CFA-5672012 https://reactome.org/PathwayBrowser/#/R-CFA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Canis familiaris 456216 R-CFA-5672027 https://reactome.org/PathwayBrowser/#/R-CFA-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Canis familiaris 456216 R-CFA-5672828 https://reactome.org/PathwayBrowser/#/R-CFA-5672828 mTORC1 phosphorylates AKT1S1 IEA Canis familiaris 456216 R-CFA-5672948 https://reactome.org/PathwayBrowser/#/R-CFA-5672948 MARK3 phosphorylates KSR1 IEA Canis familiaris 456216 R-CFA-5672969 https://reactome.org/PathwayBrowser/#/R-CFA-5672969 Phosphorylation of RAF IEA Canis familiaris 456216 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 456216 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 456216 R-CFA-5673768 https://reactome.org/PathwayBrowser/#/R-CFA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Canis familiaris 456216 R-CFA-5674130 https://reactome.org/PathwayBrowser/#/R-CFA-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Canis familiaris 456216 R-CFA-5674373 https://reactome.org/PathwayBrowser/#/R-CFA-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Canis familiaris 456216 R-CFA-5675194 https://reactome.org/PathwayBrowser/#/R-CFA-5675194 Activated MAPK phosphorylates RAF1 IEA Canis familiaris 456216 R-CFA-5675198 https://reactome.org/PathwayBrowser/#/R-CFA-5675198 Activated MAPKs phosphorylate BRAF IEA Canis familiaris 456216 R-CFA-5675868 https://reactome.org/PathwayBrowser/#/R-CFA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Canis familiaris 456216 R-CFA-5678706 https://reactome.org/PathwayBrowser/#/R-CFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Canis familiaris 456216 R-CFA-5678863 https://reactome.org/PathwayBrowser/#/R-CFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-5679041 https://reactome.org/PathwayBrowser/#/R-CFA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-5679205 https://reactome.org/PathwayBrowser/#/R-CFA-5679205 ULK1 phosphorylates Beclin-1 IEA Canis familiaris 456216 R-CFA-5682026 https://reactome.org/PathwayBrowser/#/R-CFA-5682026 MRN bound to shortened telomeres activates ATM IEA Canis familiaris 456216 R-CFA-5682101 https://reactome.org/PathwayBrowser/#/R-CFA-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Canis familiaris 456216 R-CFA-5682285 https://reactome.org/PathwayBrowser/#/R-CFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-5682598 https://reactome.org/PathwayBrowser/#/R-CFA-5682598 ATM phosphorylates HERC2 IEA Canis familiaris 456216 R-CFA-5682983 https://reactome.org/PathwayBrowser/#/R-CFA-5682983 ATM phosphorylates WHSC1 IEA Canis familiaris 456216 R-CFA-5683425 https://reactome.org/PathwayBrowser/#/R-CFA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Canis familiaris 456216 R-CFA-5683714 https://reactome.org/PathwayBrowser/#/R-CFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Canis familiaris 456216 R-CFA-5683792 https://reactome.org/PathwayBrowser/#/R-CFA-5683792 p-T68-CHEK2 autophosphorylates IEA Canis familiaris 456216 R-CFA-5683801 https://reactome.org/PathwayBrowser/#/R-CFA-5683801 CHEK2 phosphorylates BRCA1 IEA Canis familiaris 456216 R-CFA-5683964 https://reactome.org/PathwayBrowser/#/R-CFA-5683964 ATM phosphorylates EYA1-4 IEA Canis familiaris 456216 R-CFA-5684096 https://reactome.org/PathwayBrowser/#/R-CFA-5684096 CDK2 phosphorylates RBBP8 IEA Canis familiaris 456216 R-CFA-5684140 https://reactome.org/PathwayBrowser/#/R-CFA-5684140 ATM phosphorylates RBBP8 IEA Canis familiaris 456216 R-CFA-5684261 https://reactome.org/PathwayBrowser/#/R-CFA-5684261 MAP3K8 is phosphorylated IEA Canis familiaris 456216 R-CFA-5684267 https://reactome.org/PathwayBrowser/#/R-CFA-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex IEA Canis familiaris 456216 R-CFA-5684275 https://reactome.org/PathwayBrowser/#/R-CFA-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 IEA Canis familiaris 456216 R-CFA-5684806 https://reactome.org/PathwayBrowser/#/R-CFA-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN IEA Canis familiaris 456216 R-CFA-5684887 https://reactome.org/PathwayBrowser/#/R-CFA-5684887 Activation of CHEK1 at resected DNA DSBs IEA Canis familiaris 456216 R-CFA-5685156 https://reactome.org/PathwayBrowser/#/R-CFA-5685156 ATR phosphorylates RPA2 IEA Canis familiaris 456216 R-CFA-5685230 https://reactome.org/PathwayBrowser/#/R-CFA-5685230 CHEK1 phosphorylates RAD51 IEA Canis familiaris 456216 R-CFA-5686578 https://reactome.org/PathwayBrowser/#/R-CFA-5686578 Activated ATM phosphorylates ABL1 IEA Canis familiaris 456216 R-CFA-5686587 https://reactome.org/PathwayBrowser/#/R-CFA-5686587 ABL1 phosphorylates RAD52 IEA Canis familiaris 456216 R-CFA-5686704 https://reactome.org/PathwayBrowser/#/R-CFA-5686704 Activated ATM phosphorylates DCLRE1C IEA Canis familiaris 456216 R-CFA-5687086 https://reactome.org/PathwayBrowser/#/R-CFA-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Canis familiaris 456216 R-CFA-5687090 https://reactome.org/PathwayBrowser/#/R-CFA-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Canis familiaris 456216 R-CFA-5687183 https://reactome.org/PathwayBrowser/#/R-CFA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Canis familiaris 456216 R-CFA-5690702 https://reactome.org/PathwayBrowser/#/R-CFA-5690702 LYN phosphorylates CD22 IEA Canis familiaris 456216 R-CFA-5690996 https://reactome.org/PathwayBrowser/#/R-CFA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Canis familiaris 456216 R-CFA-5692462 https://reactome.org/PathwayBrowser/#/R-CFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Canis familiaris 456216 R-CFA-5692480 https://reactome.org/PathwayBrowser/#/R-CFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Canis familiaris 456216 R-CFA-5692755 https://reactome.org/PathwayBrowser/#/R-CFA-5692755 CDK1 phosphorylates MAPK6 IEA Canis familiaris 456216 R-CFA-5693148 https://reactome.org/PathwayBrowser/#/R-CFA-5693148 BCKDK phosphorylates BCKDH IEA Canis familiaris 456216 R-CFA-5693536 https://reactome.org/PathwayBrowser/#/R-CFA-5693536 ATM phosphorylates MDC1 IEA Canis familiaris 456216 R-CFA-5693540 https://reactome.org/PathwayBrowser/#/R-CFA-5693540 MRN activates ATM IEA Canis familiaris 456216 R-CFA-5693549 https://reactome.org/PathwayBrowser/#/R-CFA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Canis familiaris 456216 R-CFA-5693551 https://reactome.org/PathwayBrowser/#/R-CFA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Canis familiaris 456216 R-CFA-5693575 https://reactome.org/PathwayBrowser/#/R-CFA-5693575 DNA-PKcs autophosphorylates IEA Canis familiaris 456216 R-CFA-5693598 https://reactome.org/PathwayBrowser/#/R-CFA-5693598 ATM phosphorylates NBN IEA Canis familiaris 456216 R-CFA-5693609 https://reactome.org/PathwayBrowser/#/R-CFA-5693609 ATM phosphorylates TP53 at S15 IEA Canis familiaris 456216 R-CFA-5694441 https://reactome.org/PathwayBrowser/#/R-CFA-5694441 CSNK1D phosphorylates SEC23 IEA Canis familiaris 456216 R-CFA-5696021 https://reactome.org/PathwayBrowser/#/R-CFA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Canis familiaris 456216 R-CFA-5696074 https://reactome.org/PathwayBrowser/#/R-CFA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Canis familiaris 456216 R-CFA-5696839 https://reactome.org/PathwayBrowser/#/R-CFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Canis familiaris 456216 R-CFA-6782131 https://reactome.org/PathwayBrowser/#/R-CFA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Canis familiaris 456216 R-CFA-6784006 https://reactome.org/PathwayBrowser/#/R-CFA-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Canis familiaris 456216 R-CFA-6784319 https://reactome.org/PathwayBrowser/#/R-CFA-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Canis familiaris 456216 R-CFA-6784324 https://reactome.org/PathwayBrowser/#/R-CFA-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Canis familiaris 456216 R-CFA-6786050 https://reactome.org/PathwayBrowser/#/R-CFA-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Canis familiaris 456216 R-CFA-6786095 https://reactome.org/PathwayBrowser/#/R-CFA-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Canis familiaris 456216 R-CFA-6786096 https://reactome.org/PathwayBrowser/#/R-CFA-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Canis familiaris 456216 R-CFA-6786245 https://reactome.org/PathwayBrowser/#/R-CFA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Canis familiaris 456216 R-CFA-6787540 https://reactome.org/PathwayBrowser/#/R-CFA-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Canis familiaris 456216 R-CFA-6788392 https://reactome.org/PathwayBrowser/#/R-CFA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Canis familiaris 456216 R-CFA-6788582 https://reactome.org/PathwayBrowser/#/R-CFA-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Canis familiaris 456216 R-CFA-6788798 https://reactome.org/PathwayBrowser/#/R-CFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 456216 R-CFA-6788810 https://reactome.org/PathwayBrowser/#/R-CFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 456216 R-CFA-6788855 https://reactome.org/PathwayBrowser/#/R-CFA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Canis familiaris 456216 R-CFA-6788867 https://reactome.org/PathwayBrowser/#/R-CFA-6788867 FN3K phosphorylates ketosamines IEA Canis familiaris 456216 R-CFA-6793661 https://reactome.org/PathwayBrowser/#/R-CFA-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Canis familiaris 456216 R-CFA-6795290 https://reactome.org/PathwayBrowser/#/R-CFA-6795290 TORC2 complex phosphorylates SGK1 IEA Canis familiaris 456216 R-CFA-6795460 https://reactome.org/PathwayBrowser/#/R-CFA-6795460 SGK1 phosphorylates MDM2 IEA Canis familiaris 456216 R-CFA-6795473 https://reactome.org/PathwayBrowser/#/R-CFA-6795473 PDPK1 phosphorylates SGK1 IEA Canis familiaris 456216 R-CFA-6797606 https://reactome.org/PathwayBrowser/#/R-CFA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Canis familiaris 456216 R-CFA-6798174 https://reactome.org/PathwayBrowser/#/R-CFA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Canis familiaris 456216 R-CFA-6798372 https://reactome.org/PathwayBrowser/#/R-CFA-6798372 ATM phosphorylates DYRK2 IEA Canis familiaris 456216 R-CFA-6798374 https://reactome.org/PathwayBrowser/#/R-CFA-6798374 DYRK2 phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6799097 https://reactome.org/PathwayBrowser/#/R-CFA-6799097 ATM phosphorylates ZNF420 IEA Canis familiaris 456216 R-CFA-6799246 https://reactome.org/PathwayBrowser/#/R-CFA-6799246 CHEK1 phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6799332 https://reactome.org/PathwayBrowser/#/R-CFA-6799332 ATR phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6799409 https://reactome.org/PathwayBrowser/#/R-CFA-6799409 HIPK2 phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6799495 https://reactome.org/PathwayBrowser/#/R-CFA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Canis familiaris 456216 R-CFA-6800490 https://reactome.org/PathwayBrowser/#/R-CFA-6800490 ATM phosphorylates PIDD1 IEA Canis familiaris 456216 R-CFA-6801342 https://reactome.org/PathwayBrowser/#/R-CFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Canis familiaris 456216 R-CFA-6801456 https://reactome.org/PathwayBrowser/#/R-CFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Canis familiaris 456216 R-CFA-6801666 https://reactome.org/PathwayBrowser/#/R-CFA-6801666 PLK2 phosphorylates CENPJ IEA Canis familiaris 456216 R-CFA-6801675 https://reactome.org/PathwayBrowser/#/R-CFA-6801675 PLK2 phosphorylates NPM1 IEA Canis familiaris 456216 R-CFA-6802973 https://reactome.org/PathwayBrowser/#/R-CFA-6802973 PLK3 phosphorylates CDC25C IEA Canis familiaris 456216 R-CFA-6803545 https://reactome.org/PathwayBrowser/#/R-CFA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Canis familiaris 456216 R-CFA-6803771 https://reactome.org/PathwayBrowser/#/R-CFA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Canis familiaris 456216 R-CFA-6804266 https://reactome.org/PathwayBrowser/#/R-CFA-6804266 CHEK2 phosphorylates TTC5 IEA Canis familiaris 456216 R-CFA-6804276 https://reactome.org/PathwayBrowser/#/R-CFA-6804276 ATM phosphorylates TTC5 IEA Canis familiaris 456216 R-CFA-6804955 https://reactome.org/PathwayBrowser/#/R-CFA-6804955 ATM phosphorylates MDM2 IEA Canis familiaris 456216 R-CFA-6805059 https://reactome.org/PathwayBrowser/#/R-CFA-6805059 CK2:FACT phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6805103 https://reactome.org/PathwayBrowser/#/R-CFA-6805103 AURKA phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6805109 https://reactome.org/PathwayBrowser/#/R-CFA-6805109 CDK2 phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6805126 https://reactome.org/PathwayBrowser/#/R-CFA-6805126 AURKB phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6805276 https://reactome.org/PathwayBrowser/#/R-CFA-6805276 CDK5 phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6805285 https://reactome.org/PathwayBrowser/#/R-CFA-6805285 PLK3 phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6805399 https://reactome.org/PathwayBrowser/#/R-CFA-6805399 TAF1 phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6805470 https://reactome.org/PathwayBrowser/#/R-CFA-6805470 AMPK phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6805479 https://reactome.org/PathwayBrowser/#/R-CFA-6805479 TP53RK phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-6805507 https://reactome.org/PathwayBrowser/#/R-CFA-6805507 APAF1 binds AVEN IEA Canis familiaris 456216 R-CFA-6806877 https://reactome.org/PathwayBrowser/#/R-CFA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Canis familiaris 456216 R-CFA-6806967 https://reactome.org/PathwayBrowser/#/R-CFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Canis familiaris 456216 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 456216 R-CFA-6807868 https://reactome.org/PathwayBrowser/#/R-CFA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Canis familiaris 456216 R-CFA-6810233 https://reactome.org/PathwayBrowser/#/R-CFA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Canis familiaris 456216 R-CFA-6810472 https://reactome.org/PathwayBrowser/#/R-CFA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Canis familiaris 456216 R-CFA-6811454 https://reactome.org/PathwayBrowser/#/R-CFA-6811454 MAPKs phosphorylate PP2A IEA Canis familiaris 456216 R-CFA-6811522 https://reactome.org/PathwayBrowser/#/R-CFA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Canis familiaris 456216 R-CFA-6814119 https://reactome.org/PathwayBrowser/#/R-CFA-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Canis familiaris 456216 R-CFA-6814120 https://reactome.org/PathwayBrowser/#/R-CFA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Canis familiaris 456216 R-CFA-6814121 https://reactome.org/PathwayBrowser/#/R-CFA-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Canis familiaris 456216 R-CFA-6814124 https://reactome.org/PathwayBrowser/#/R-CFA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Canis familiaris 456216 R-CFA-6814409 https://reactome.org/PathwayBrowser/#/R-CFA-6814409 CK2 phosphorylates PDCL IEA Canis familiaris 456216 R-CFA-6814670 https://reactome.org/PathwayBrowser/#/R-CFA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Canis familiaris 456216 R-CFA-6814678 https://reactome.org/PathwayBrowser/#/R-CFA-6814678 ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN IEA Canis familiaris 456216 R-CFA-68944 https://reactome.org/PathwayBrowser/#/R-CFA-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Canis familiaris 456216 R-CFA-69005 https://reactome.org/PathwayBrowser/#/R-CFA-69005 Cdc6 protein is phosphorylated by CDK IEA Canis familiaris 456216 R-CFA-69063 https://reactome.org/PathwayBrowser/#/R-CFA-69063 Loading of PCNA - Sliding Clamp Formation IEA Canis familiaris 456216 R-CFA-69195 https://reactome.org/PathwayBrowser/#/R-CFA-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Canis familiaris 456216 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 456216 R-CFA-69604 https://reactome.org/PathwayBrowser/#/R-CFA-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Canis familiaris 456216 R-CFA-69608 https://reactome.org/PathwayBrowser/#/R-CFA-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Canis familiaris 456216 R-CFA-69685 https://reactome.org/PathwayBrowser/#/R-CFA-69685 CHEK2 phosphorylates TP53 IEA Canis familiaris 456216 R-CFA-69891 https://reactome.org/PathwayBrowser/#/R-CFA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Canis familiaris 456216 R-CFA-70349 https://reactome.org/PathwayBrowser/#/R-CFA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Canis familiaris 456216 R-CFA-70355 https://reactome.org/PathwayBrowser/#/R-CFA-70355 GALK1 phosphorylates Gal to Gal1P IEA Canis familiaris 456216 R-CFA-70420 https://reactome.org/PathwayBrowser/#/R-CFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Canis familiaris 456216 R-CFA-70467 https://reactome.org/PathwayBrowser/#/R-CFA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Canis familiaris 456216 R-CFA-70486 https://reactome.org/PathwayBrowser/#/R-CFA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Canis familiaris 456216 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 456216 R-CFA-70555 https://reactome.org/PathwayBrowser/#/R-CFA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Canis familiaris 456216 R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Canis familiaris 456216 R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Canis familiaris 456216 R-CFA-70606 https://reactome.org/PathwayBrowser/#/R-CFA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Canis familiaris 456216 R-CFA-70773 https://reactome.org/PathwayBrowser/#/R-CFA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Canis familiaris 456216 R-CFA-70967 https://reactome.org/PathwayBrowser/#/R-CFA-70967 IDH3 complex decarboxylates isocitrate IEA Canis familiaris 456216 R-CFA-70997 https://reactome.org/PathwayBrowser/#/R-CFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Canis familiaris 456216 R-CFA-71031 https://reactome.org/PathwayBrowser/#/R-CFA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Canis familiaris 456216 R-CFA-71401 https://reactome.org/PathwayBrowser/#/R-CFA-71401 OGDH dimer decarboxylates 2-OG IEA Canis familiaris 456216 R-CFA-71541 https://reactome.org/PathwayBrowser/#/R-CFA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Canis familiaris 456216 R-CFA-71588 https://reactome.org/PathwayBrowser/#/R-CFA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Canis familiaris 456216 R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 456216 R-CFA-71802 https://reactome.org/PathwayBrowser/#/R-CFA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Canis familiaris 456216 R-CFA-71850 https://reactome.org/PathwayBrowser/#/R-CFA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Canis familiaris 456216 R-CFA-72621 https://reactome.org/PathwayBrowser/#/R-CFA-72621 Ribosomal scanning IEA Canis familiaris 456216 R-CFA-72647 https://reactome.org/PathwayBrowser/#/R-CFA-72647 Cap-bound mRNA is activated by helicases IEA Canis familiaris 456216 R-CFA-727819 https://reactome.org/PathwayBrowser/#/R-CFA-727819 TAK1 phosphorylates MKK6 IEA Canis familiaris 456216 R-CFA-73548 https://reactome.org/PathwayBrowser/#/R-CFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Canis familiaris 456216 R-CFA-73577 https://reactome.org/PathwayBrowser/#/R-CFA-73577 CAD hexamer transforms L-Gln to CAP IEA Canis familiaris 456216 R-CFA-73598 https://reactome.org/PathwayBrowser/#/R-CFA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Canis familiaris 456216 R-CFA-73599 https://reactome.org/PathwayBrowser/#/R-CFA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Canis familiaris 456216 R-CFA-73632 https://reactome.org/PathwayBrowser/#/R-CFA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Canis familiaris 456216 R-CFA-73635 https://reactome.org/PathwayBrowser/#/R-CFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Canis familiaris 456216 R-CFA-73647 https://reactome.org/PathwayBrowser/#/R-CFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Canis familiaris 456216 R-CFA-73722 https://reactome.org/PathwayBrowser/#/R-CFA-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Canis familiaris 456216 R-CFA-73788 https://reactome.org/PathwayBrowser/#/R-CFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Canis familiaris 456216 R-CFA-73805 https://reactome.org/PathwayBrowser/#/R-CFA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Canis familiaris 456216 R-CFA-73810 https://reactome.org/PathwayBrowser/#/R-CFA-73810 FGAM + ATP => AIR + ADP + Pi IEA Canis familiaris 456216 R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 456216 R-CFA-73814 https://reactome.org/PathwayBrowser/#/R-CFA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Canis familiaris 456216 R-CFA-74207 https://reactome.org/PathwayBrowser/#/R-CFA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Canis familiaris 456216 R-CFA-74220 https://reactome.org/PathwayBrowser/#/R-CFA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Canis familiaris 456216 R-CFA-74711 https://reactome.org/PathwayBrowser/#/R-CFA-74711 Phosphorylation of IRS IEA Canis familiaris 456216 R-CFA-74715 https://reactome.org/PathwayBrowser/#/R-CFA-74715 Autophosphorylation of insulin receptor IEA Canis familiaris 456216 R-CFA-74742 https://reactome.org/PathwayBrowser/#/R-CFA-74742 Phosphorylation of SHC1 IEA Canis familiaris 456216 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 456216 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 456216 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 456216 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 456216 R-CFA-75010 https://reactome.org/PathwayBrowser/#/R-CFA-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Canis familiaris 456216 R-CFA-75125 https://reactome.org/PathwayBrowser/#/R-CFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Canis familiaris 456216 R-CFA-75126 https://reactome.org/PathwayBrowser/#/R-CFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Canis familiaris 456216 R-CFA-75809 https://reactome.org/PathwayBrowser/#/R-CFA-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Canis familiaris 456216 R-CFA-75848 https://reactome.org/PathwayBrowser/#/R-CFA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Canis familiaris 456216 R-CFA-75851 https://reactome.org/PathwayBrowser/#/R-CFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 456216 R-CFA-75887 https://reactome.org/PathwayBrowser/#/R-CFA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Canis familiaris 456216 R-CFA-75949 https://reactome.org/PathwayBrowser/#/R-CFA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Canis familiaris 456216 R-CFA-77071 https://reactome.org/PathwayBrowser/#/R-CFA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Canis familiaris 456216 R-CFA-873918 https://reactome.org/PathwayBrowser/#/R-CFA-873918 Transphosphorylation of JAK1 IEA Canis familiaris 456216 R-CFA-873919 https://reactome.org/PathwayBrowser/#/R-CFA-873919 Phosphorylation of JAK2 IEA Canis familiaris 456216 R-CFA-873922 https://reactome.org/PathwayBrowser/#/R-CFA-873922 Phosphorylation of STAT1 by JAK kinases IEA Canis familiaris 456216 R-CFA-873924 https://reactome.org/PathwayBrowser/#/R-CFA-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Canis familiaris 456216 R-CFA-879907 https://reactome.org/PathwayBrowser/#/R-CFA-879907 Tyrosine kinases phosphorylate the receptor IEA Canis familiaris 456216 R-CFA-879909 https://reactome.org/PathwayBrowser/#/R-CFA-879909 Activation of STAT5a/b by JAK2 IEA Canis familiaris 456216 R-CFA-879910 https://reactome.org/PathwayBrowser/#/R-CFA-879910 JAK2 is phosphorylated, activated IEA Canis familiaris 456216 R-CFA-8847638 https://reactome.org/PathwayBrowser/#/R-CFA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Canis familiaris 456216 R-CFA-8847977 https://reactome.org/PathwayBrowser/#/R-CFA-8847977 FRK phosphorylates PTEN IEA Canis familiaris 456216 R-CFA-8848053 https://reactome.org/PathwayBrowser/#/R-CFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Canis familiaris 456216 R-CFA-8850527 https://reactome.org/PathwayBrowser/#/R-CFA-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Canis familiaris 456216 R-CFA-8850529 https://reactome.org/PathwayBrowser/#/R-CFA-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Canis familiaris 456216 R-CFA-8850534 https://reactome.org/PathwayBrowser/#/R-CFA-8850534 PDCL promotes G-protein beta 5 folding IEA Canis familiaris 456216 R-CFA-8850539 https://reactome.org/PathwayBrowser/#/R-CFA-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Canis familiaris 456216 R-CFA-8850945 https://reactome.org/PathwayBrowser/#/R-CFA-8850945 Casein kinase II phosphorylates PTEN IEA Canis familiaris 456216 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 456216 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 456216 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 456216 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 456216 R-CFA-8851797 https://reactome.org/PathwayBrowser/#/R-CFA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Canis familiaris 456216 R-CFA-8851890 https://reactome.org/PathwayBrowser/#/R-CFA-8851890 MET phosphorylates SHC1-2 IEA Canis familiaris 456216 R-CFA-8851933 https://reactome.org/PathwayBrowser/#/R-CFA-8851933 MET phosphorylates GAB1 IEA Canis familiaris 456216 R-CFA-8852019 https://reactome.org/PathwayBrowser/#/R-CFA-8852019 MET bound PI3K generates PIP3 IEA Canis familiaris 456216 R-CFA-8852306 https://reactome.org/PathwayBrowser/#/R-CFA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Canis familiaris 456216 R-CFA-8852317 https://reactome.org/PathwayBrowser/#/R-CFA-8852317 PLK1 phosphorylates GTSE1 IEA Canis familiaris 456216 R-CFA-8852552 https://reactome.org/PathwayBrowser/#/R-CFA-8852552 MST1R autophosphorylates IEA Canis familiaris 456216 R-CFA-8853419 https://reactome.org/PathwayBrowser/#/R-CFA-8853419 TPX2 promotes AURKA autophosphorylation IEA Canis familiaris 456216 R-CFA-8853444 https://reactome.org/PathwayBrowser/#/R-CFA-8853444 AURKA phosphorylates PHLDA1 IEA Canis familiaris 456216 R-CFA-8853774 https://reactome.org/PathwayBrowser/#/R-CFA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Canis familiaris 456216 R-CFA-8853792 https://reactome.org/PathwayBrowser/#/R-CFA-8853792 RET tyrosine phosphorylation IEA Canis familiaris 456216 R-CFA-8854908 https://reactome.org/PathwayBrowser/#/R-CFA-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Canis familiaris 456216 R-CFA-8855237 https://reactome.org/PathwayBrowser/#/R-CFA-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Canis familiaris 456216 R-CFA-8856813 https://reactome.org/PathwayBrowser/#/R-CFA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Canis familiaris 456216 R-CFA-8857925 https://reactome.org/PathwayBrowser/#/R-CFA-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Canis familiaris 456216 R-CFA-8865774 https://reactome.org/PathwayBrowser/#/R-CFA-8865774 TTLLs polyglutamylate tubulin IEA Canis familiaris 456216 R-CFA-8866268 https://reactome.org/PathwayBrowser/#/R-CFA-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Canis familiaris 456216 R-CFA-8866542 https://reactome.org/PathwayBrowser/#/R-CFA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Canis familiaris 456216 R-CFA-8867041 https://reactome.org/PathwayBrowser/#/R-CFA-8867041 EGFR phosphorylates EPS15 IEA Canis familiaris 456216 R-CFA-8867370 https://reactome.org/PathwayBrowser/#/R-CFA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Canis familiaris 456216 R-CFA-8868066 https://reactome.org/PathwayBrowser/#/R-CFA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Canis familiaris 456216 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 456216 R-CFA-8868118 https://reactome.org/PathwayBrowser/#/R-CFA-8868118 MAPK12 phosphorylates PTPN3 IEA Canis familiaris 456216 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 456216 R-CFA-8869606 https://reactome.org/PathwayBrowser/#/R-CFA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Canis familiaris 456216 R-CFA-8869633 https://reactome.org/PathwayBrowser/#/R-CFA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Canis familiaris 456216 R-CFA-8871373 https://reactome.org/PathwayBrowser/#/R-CFA-8871373 BMX phosphorylates RUFY1 IEA Canis familiaris 456216 R-CFA-8873929 https://reactome.org/PathwayBrowser/#/R-CFA-8873929 Casein kinase II phosphorylates STARD10 IEA Canis familiaris 456216 R-CFA-8874078 https://reactome.org/PathwayBrowser/#/R-CFA-8874078 PTK2 autophosphorylates IEA Canis familiaris 456216 R-CFA-8874080 https://reactome.org/PathwayBrowser/#/R-CFA-8874080 SRC phosphorylates PTK2 IEA Canis familiaris 456216 R-CFA-8874082 https://reactome.org/PathwayBrowser/#/R-CFA-8874082 MET phosphorylates PTK2 IEA Canis familiaris 456216 R-CFA-8875451 https://reactome.org/PathwayBrowser/#/R-CFA-8875451 MET phosphorylates CBL IEA Canis familiaris 456216 R-CFA-8875817 https://reactome.org/PathwayBrowser/#/R-CFA-8875817 MET phosphorylates STAT3 IEA Canis familiaris 456216 R-CFA-8876446 https://reactome.org/PathwayBrowser/#/R-CFA-8876446 p-ULK1 phosphorylates DENND3 IEA Canis familiaris 456216 R-CFA-8876889 https://reactome.org/PathwayBrowser/#/R-CFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 456216 R-CFA-8877691 https://reactome.org/PathwayBrowser/#/R-CFA-8877691 MAP2K6 phosphorylates PIP4K2B IEA Canis familiaris 456216 R-CFA-8878050 https://reactome.org/PathwayBrowser/#/R-CFA-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Canis familiaris 456216 R-CFA-8878054 https://reactome.org/PathwayBrowser/#/R-CFA-8878054 HIPK2 phosphorylates RUNX1 IEA Canis familiaris 456216 R-CFA-8931653 https://reactome.org/PathwayBrowser/#/R-CFA-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Canis familiaris 456216 R-CFA-8934446 https://reactome.org/PathwayBrowser/#/R-CFA-8934446 Activated PKC phosphorylates SHC1 IEA Canis familiaris 456216 R-CFA-8937807 https://reactome.org/PathwayBrowser/#/R-CFA-8937807 SRC phosphorylates RUNX3 IEA Canis familiaris 456216 R-CFA-8940100 https://reactome.org/PathwayBrowser/#/R-CFA-8940100 CDK1 phosphorylates VCPIP1 IEA Canis familiaris 456216 R-CFA-8942575 https://reactome.org/PathwayBrowser/#/R-CFA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Canis familiaris 456216 R-CFA-8942607 https://reactome.org/PathwayBrowser/#/R-CFA-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Canis familiaris 456216 R-CFA-8942836 https://reactome.org/PathwayBrowser/#/R-CFA-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Canis familiaris 456216 R-CFA-8944454 https://reactome.org/PathwayBrowser/#/R-CFA-8944454 mTORC1 phosphorylates MAF1 IEA Canis familiaris 456216 R-CFA-8948039 https://reactome.org/PathwayBrowser/#/R-CFA-8948039 FUNDC1 is phosphorylated by CK2 IEA Canis familiaris 456216 R-CFA-8948143 https://reactome.org/PathwayBrowser/#/R-CFA-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Canis familiaris 456216 R-CFA-8948146 https://reactome.org/PathwayBrowser/#/R-CFA-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Canis familiaris 456216 R-CFA-8950269 https://reactome.org/PathwayBrowser/#/R-CFA-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Canis familiaris 456216 R-CFA-8950340 https://reactome.org/PathwayBrowser/#/R-CFA-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Canis familiaris 456216 R-CFA-8950405 https://reactome.org/PathwayBrowser/#/R-CFA-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Canis familiaris 456216 R-CFA-8950423 https://reactome.org/PathwayBrowser/#/R-CFA-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Canis familiaris 456216 R-CFA-8950453 https://reactome.org/PathwayBrowser/#/R-CFA-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Canis familiaris 456216 R-CFA-8950485 https://reactome.org/PathwayBrowser/#/R-CFA-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Canis familiaris 456216 R-CFA-8950537 https://reactome.org/PathwayBrowser/#/R-CFA-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Canis familiaris 456216 R-CFA-8950757 https://reactome.org/PathwayBrowser/#/R-CFA-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Canis familiaris 456216 R-CFA-8952289 https://reactome.org/PathwayBrowser/#/R-CFA-8952289 FAM20C phosphorylates FAM20C substrates IEA Canis familiaris 456216 R-CFA-8954327 https://reactome.org/PathwayBrowser/#/R-CFA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Canis familiaris 456216 R-CFA-8955030 https://reactome.org/PathwayBrowser/#/R-CFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Canis familiaris 456216 R-CFA-8955844 https://reactome.org/PathwayBrowser/#/R-CFA-8955844 RBKS phosphorylates ribose to R5P IEA Canis familiaris 456216 R-CFA-8956659 https://reactome.org/PathwayBrowser/#/R-CFA-8956659 ABL1 phosphorylates YAP1 IEA Canis familiaris 456216 R-CFA-8959719 https://reactome.org/PathwayBrowser/#/R-CFA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Canis familiaris 456216 R-CFA-8964242 https://reactome.org/PathwayBrowser/#/R-CFA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Canis familiaris 456216 R-CFA-8982163 https://reactome.org/PathwayBrowser/#/R-CFA-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Canis familiaris 456216 R-CFA-8983059 https://reactome.org/PathwayBrowser/#/R-CFA-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Canis familiaris 456216 R-CFA-8983063 https://reactome.org/PathwayBrowser/#/R-CFA-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Canis familiaris 456216 R-CFA-8983300 https://reactome.org/PathwayBrowser/#/R-CFA-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Canis familiaris 456216 R-CFA-8983371 https://reactome.org/PathwayBrowser/#/R-CFA-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Canis familiaris 456216 R-CFA-8983834 https://reactome.org/PathwayBrowser/#/R-CFA-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Canis familiaris 456216 R-CFA-8983835 https://reactome.org/PathwayBrowser/#/R-CFA-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Canis familiaris 456216 R-CFA-8983870 https://reactome.org/PathwayBrowser/#/R-CFA-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Canis familiaris 456216 R-CFA-8983872 https://reactome.org/PathwayBrowser/#/R-CFA-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Canis familiaris 456216 R-CFA-8984012 https://reactome.org/PathwayBrowser/#/R-CFA-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Canis familiaris 456216 R-CFA-8984014 https://reactome.org/PathwayBrowser/#/R-CFA-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Canis familiaris 456216 R-CFA-8985914 https://reactome.org/PathwayBrowser/#/R-CFA-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Canis familiaris 456216 R-CFA-8985973 https://reactome.org/PathwayBrowser/#/R-CFA-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Canis familiaris 456216 R-CFA-8985988 https://reactome.org/PathwayBrowser/#/R-CFA-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Canis familiaris 456216 R-CFA-8986985 https://reactome.org/PathwayBrowser/#/R-CFA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Canis familiaris 456216 R-CFA-8986994 https://reactome.org/PathwayBrowser/#/R-CFA-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Canis familiaris 456216 R-CFA-8986995 https://reactome.org/PathwayBrowser/#/R-CFA-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Canis familiaris 456216 R-CFA-8987012 https://reactome.org/PathwayBrowser/#/R-CFA-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Canis familiaris 456216 R-CFA-8987040 https://reactome.org/PathwayBrowser/#/R-CFA-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Canis familiaris 456216 R-CFA-8987042 https://reactome.org/PathwayBrowser/#/R-CFA-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Canis familiaris 456216 R-CFA-8987070 https://reactome.org/PathwayBrowser/#/R-CFA-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Canis familiaris 456216 R-CFA-8987084 https://reactome.org/PathwayBrowser/#/R-CFA-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Canis familiaris 456216 R-CFA-8987096 https://reactome.org/PathwayBrowser/#/R-CFA-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Canis familiaris 456216 R-CFA-8987129 https://reactome.org/PathwayBrowser/#/R-CFA-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Canis familiaris 456216 R-CFA-8987141 https://reactome.org/PathwayBrowser/#/R-CFA-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Canis familiaris 456216 R-CFA-8987150 https://reactome.org/PathwayBrowser/#/R-CFA-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Canis familiaris 456216 R-CFA-8987179 https://reactome.org/PathwayBrowser/#/R-CFA-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Canis familiaris 456216 R-CFA-8987202 https://reactome.org/PathwayBrowser/#/R-CFA-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Canis familiaris 456216 R-CFA-8987255 https://reactome.org/PathwayBrowser/#/R-CFA-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Canis familiaris 456216 R-CFA-9006850 https://reactome.org/PathwayBrowser/#/R-CFA-9006850 IL21 receptor JAK phosphorylation IEA Canis familiaris 456216 R-CFA-9006870 https://reactome.org/PathwayBrowser/#/R-CFA-9006870 IL21 receptor STAT phosphorylation IEA Canis familiaris 456216 R-CFA-9007539 https://reactome.org/PathwayBrowser/#/R-CFA-9007539 CHEK1 phosphorylates E2F6 IEA Canis familiaris 456216 R-CFA-9008043 https://reactome.org/PathwayBrowser/#/R-CFA-9008043 MAPK8 phosphorylation IEA Canis familiaris 456216 R-CFA-9008412 https://reactome.org/PathwayBrowser/#/R-CFA-9008412 CDK4 phosphorylates RUNX2 IEA Canis familiaris 456216 R-CFA-9008684 https://reactome.org/PathwayBrowser/#/R-CFA-9008684 TBK1 phosphorylation IEA Canis familiaris 456216 R-CFA-9009072 https://reactome.org/PathwayBrowser/#/R-CFA-9009072 STAT3 phosphorylation IEA Canis familiaris 456216 R-CFA-9009282 https://reactome.org/PathwayBrowser/#/R-CFA-9009282 CDK1 phosphorylates RUNX2 IEA Canis familiaris 456216 R-CFA-9010681 https://reactome.org/PathwayBrowser/#/R-CFA-9010681 PKC phosphorylates ROBO3.1 IEA Canis familiaris 456216 R-CFA-9012319 https://reactome.org/PathwayBrowser/#/R-CFA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Canis familiaris 456216 R-CFA-9021357 https://reactome.org/PathwayBrowser/#/R-CFA-9021357 PRKCI phosphorylates ELF3 IEA Canis familiaris 456216 R-CFA-9021609 https://reactome.org/PathwayBrowser/#/R-CFA-9021609 ESR-associated SRC autophosphorylates IEA Canis familiaris 456216 R-CFA-9021627 https://reactome.org/PathwayBrowser/#/R-CFA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 456216 R-CFA-9022314 https://reactome.org/PathwayBrowser/#/R-CFA-9022314 HIPK2 phosphorylates MECP2 IEA Canis familiaris 456216 R-CFA-9027272 https://reactome.org/PathwayBrowser/#/R-CFA-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Canis familiaris 456216 R-CFA-9027273 https://reactome.org/PathwayBrowser/#/R-CFA-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Canis familiaris 456216 R-CFA-9034714 https://reactome.org/PathwayBrowser/#/R-CFA-9034714 NTRK3 dimers trans-autophosphorylate IEA Canis familiaris 456216 R-CFA-909552 https://reactome.org/PathwayBrowser/#/R-CFA-909552 Phosphorylation of STAT1 at Ser727 IEA Canis familiaris 456216 R-CFA-909718 https://reactome.org/PathwayBrowser/#/R-CFA-909718 Formation of p-STAT1 homodimer IEA Canis familiaris 456216 R-CFA-909729 https://reactome.org/PathwayBrowser/#/R-CFA-909729 Activation of JAK kinases IEA Canis familiaris 456216 R-CFA-909730 https://reactome.org/PathwayBrowser/#/R-CFA-909730 Phosphorylation of INFAR1 by TYK2 IEA Canis familiaris 456216 R-CFA-909732 https://reactome.org/PathwayBrowser/#/R-CFA-909732 Phosphorylation of STAT2 IEA Canis familiaris 456216 R-CFA-912527 https://reactome.org/PathwayBrowser/#/R-CFA-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Canis familiaris 456216 R-CFA-913996 https://reactome.org/PathwayBrowser/#/R-CFA-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Canis familiaris 456216 R-CFA-917841 https://reactome.org/PathwayBrowser/#/R-CFA-917841 Acidification of Tf:TfR1 containing endosome IEA Canis familiaris 456216 R-CFA-917979 https://reactome.org/PathwayBrowser/#/R-CFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-927889 https://reactome.org/PathwayBrowser/#/R-CFA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Canis familiaris 456216 R-CFA-934559 https://reactome.org/PathwayBrowser/#/R-CFA-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Canis familiaris 456216 R-CFA-936802 https://reactome.org/PathwayBrowser/#/R-CFA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Canis familiaris 456216 R-CFA-936883 https://reactome.org/PathwayBrowser/#/R-CFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Canis familiaris 456216 R-CFA-936895 https://reactome.org/PathwayBrowser/#/R-CFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Canis familiaris 456216 R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 456216 R-CFA-936951 https://reactome.org/PathwayBrowser/#/R-CFA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Canis familiaris 456216 R-CFA-936991 https://reactome.org/PathwayBrowser/#/R-CFA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Canis familiaris 456216 R-CFA-937034 https://reactome.org/PathwayBrowser/#/R-CFA-937034 IRAK1 phosphorylates Pellino IEA Canis familiaris 456216 R-CFA-937311 https://reactome.org/PathwayBrowser/#/R-CFA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Canis familiaris 456216 R-CFA-939763 https://reactome.org/PathwayBrowser/#/R-CFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Canis familiaris 456216 R-CFA-947591 https://reactome.org/PathwayBrowser/#/R-CFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Canis familiaris 456216 R-CFA-9603420 https://reactome.org/PathwayBrowser/#/R-CFA-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Canis familiaris 456216 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 456216 R-CFA-9606884 https://reactome.org/PathwayBrowser/#/R-CFA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Canis familiaris 456216 R-CFA-9612501 https://reactome.org/PathwayBrowser/#/R-CFA-9612501 SGK phosphorylates CREB1 IEA Canis familiaris 456216 R-CFA-9612509 https://reactome.org/PathwayBrowser/#/R-CFA-9612509 SGK phosphorylates SRF IEA Canis familiaris 456216 R-CFA-9619355 https://reactome.org/PathwayBrowser/#/R-CFA-9619355 CaMKK autophosphorylates in the cytosol IEA Canis familiaris 456216 R-CFA-9624800 https://reactome.org/PathwayBrowser/#/R-CFA-9624800 CDK1 phosphorylates LBR IEA Canis familiaris 456216 R-CFA-9625487 https://reactome.org/PathwayBrowser/#/R-CFA-9625487 PTK2 autophosphorylates downstream of EGFR IEA Canis familiaris 456216 R-CFA-9626817 https://reactome.org/PathwayBrowser/#/R-CFA-9626817 PKC phosphorylates NCF1 IEA Canis familiaris 456216 R-CFA-9626832 https://reactome.org/PathwayBrowser/#/R-CFA-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Canis familiaris 456216 R-CFA-9626880 https://reactome.org/PathwayBrowser/#/R-CFA-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Canis familiaris 456216 R-CFA-9627089 https://reactome.org/PathwayBrowser/#/R-CFA-9627089 CASP9 is phosphorylated at T412 IEA Canis familiaris 456216 R-CFA-9632858 https://reactome.org/PathwayBrowser/#/R-CFA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Canis familiaris 456216 R-CFA-9632868 https://reactome.org/PathwayBrowser/#/R-CFA-9632868 CDKN1B is phosphorylated in response to estrogen IEA Canis familiaris 456216 R-CFA-9645442 https://reactome.org/PathwayBrowser/#/R-CFA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Canis familiaris 456216 R-CFA-9645535 https://reactome.org/PathwayBrowser/#/R-CFA-9645535 ALPK1 phosphorylates TIFA IEA Canis familiaris 456216 R-CFA-9648089 https://reactome.org/PathwayBrowser/#/R-CFA-9648089 NEK6 and NEK7 phosphorylate EML4 IEA Canis familiaris 456216 R-CFA-964958 https://reactome.org/PathwayBrowser/#/R-CFA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Canis familiaris 456216 R-CFA-964962 https://reactome.org/PathwayBrowser/#/R-CFA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Canis familiaris 456216 R-CFA-964970 https://reactome.org/PathwayBrowser/#/R-CFA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Canis familiaris 456216 R-CFA-9650858 https://reactome.org/PathwayBrowser/#/R-CFA-9650858 Meglitinides bind ABCC8 IEA Canis familiaris 456216 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 456216 R-CFA-9653503 https://reactome.org/PathwayBrowser/#/R-CFA-9653503 KRAS4B is phosphorylated on serine 181 IEA Canis familiaris 456216 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 456216 R-CFA-9661417 https://reactome.org/PathwayBrowser/#/R-CFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-9668419 https://reactome.org/PathwayBrowser/#/R-CFA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Canis familiaris 456216 R-CFA-9684118 https://reactome.org/PathwayBrowser/#/R-CFA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Canis familiaris 456216 R-CFA-9686521 https://reactome.org/PathwayBrowser/#/R-CFA-9686521 CDK2:CCNA phosphorylates TERF2 IEA Canis familiaris 456216 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 456216 R-CFA-9699578 https://reactome.org/PathwayBrowser/#/R-CFA-9699578 Active FLT3 phosphorylates CDKN1B IEA Canis familiaris 456216 R-CFA-9700168 https://reactome.org/PathwayBrowser/#/R-CFA-9700168 Active ALK phosphorylates IRS1 IEA Canis familiaris 456216 R-CFA-9700171 https://reactome.org/PathwayBrowser/#/R-CFA-9700171 Active ALK phosphorylates PLCG1 IEA Canis familiaris 456216 R-CFA-9700175 https://reactome.org/PathwayBrowser/#/R-CFA-9700175 Active ALK phosphorylates SHC1 IEA Canis familiaris 456216 R-CFA-9701488 https://reactome.org/PathwayBrowser/#/R-CFA-9701488 Active ALK phosphorylates JAK3 IEA Canis familiaris 456216 R-CFA-9706344 https://reactome.org/PathwayBrowser/#/R-CFA-9706344 FLT3 phosphorylates GRB10 IEA Canis familiaris 456216 R-CFA-9706350 https://reactome.org/PathwayBrowser/#/R-CFA-9706350 FLT3 phosphorylates CBL IEA Canis familiaris 456216 R-CFA-9706399 https://reactome.org/PathwayBrowser/#/R-CFA-9706399 RHOBTB3 hydrolyzes ATP IEA Canis familiaris 456216 R-CFA-9727198 https://reactome.org/PathwayBrowser/#/R-CFA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Canis familiaris 456216 R-CFA-9731111 https://reactome.org/PathwayBrowser/#/R-CFA-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Canis familiaris 456216 R-CFA-9732738 https://reactome.org/PathwayBrowser/#/R-CFA-9732738 JAK1-mediated phosphorylation of RAF1 IEA Canis familiaris 456216 R-CFA-9732753 https://reactome.org/PathwayBrowser/#/R-CFA-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Canis familiaris 456216 R-CFA-9734547 https://reactome.org/PathwayBrowser/#/R-CFA-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Canis familiaris 456216 R-CFA-9734687 https://reactome.org/PathwayBrowser/#/R-CFA-9734687 ORC6 is phosphorylated on T195 IEA Canis familiaris 456216 R-CFA-9748949 https://reactome.org/PathwayBrowser/#/R-CFA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Canis familiaris 456216 R-CFA-9748963 https://reactome.org/PathwayBrowser/#/R-CFA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Canis familiaris 456216 R-CFA-9748969 https://reactome.org/PathwayBrowser/#/R-CFA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Canis familiaris 456216 R-CFA-9748999 https://reactome.org/PathwayBrowser/#/R-CFA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Canis familiaris 456216 R-CFA-9750546 https://reactome.org/PathwayBrowser/#/R-CFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-9750617 https://reactome.org/PathwayBrowser/#/R-CFA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-9750656 https://reactome.org/PathwayBrowser/#/R-CFA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Canis familiaris 456216 R-CFA-975103 https://reactome.org/PathwayBrowser/#/R-CFA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Canis familiaris 456216 R-CFA-975139 https://reactome.org/PathwayBrowser/#/R-CFA-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Canis familiaris 456216 R-CFA-9753278 https://reactome.org/PathwayBrowser/#/R-CFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 456216 R-CFA-9753283 https://reactome.org/PathwayBrowser/#/R-CFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 456216 R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 456216 R-CFA-9754974 https://reactome.org/PathwayBrowser/#/R-CFA-9754974 ADK phosphorylates RBV IEA Canis familiaris 456216 R-CFA-9755013 https://reactome.org/PathwayBrowser/#/R-CFA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Canis familiaris 456216 R-CFA-9759206 https://reactome.org/PathwayBrowser/#/R-CFA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Canis familiaris 456216 R-CFA-9759454 https://reactome.org/PathwayBrowser/#/R-CFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Canis familiaris 456216 R-CFA-9759461 https://reactome.org/PathwayBrowser/#/R-CFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Canis familiaris 456216 R-CFA-9760094 https://reactome.org/PathwayBrowser/#/R-CFA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Canis familiaris 456216 R-CFA-9762094 https://reactome.org/PathwayBrowser/#/R-CFA-9762094 GSK3B phosphorylates p-NFE2L2 IEA Canis familiaris 456216 R-CFA-9770141 https://reactome.org/PathwayBrowser/#/R-CFA-9770141 Formation of the Spliceosomal C* complex IEA Canis familiaris 456216 R-CFA-9770142 https://reactome.org/PathwayBrowser/#/R-CFA-9770142 Formation of the Spliceosomal B complex IEA Canis familiaris 456216 R-CFA-9773803 https://reactome.org/PathwayBrowser/#/R-CFA-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Canis familiaris 456216 R-CFA-9794120 https://reactome.org/PathwayBrowser/#/R-CFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Canis familiaris 456216 R-CFA-9794572 https://reactome.org/PathwayBrowser/#/R-CFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Canis familiaris 456216 R-CFA-9796053 https://reactome.org/PathwayBrowser/#/R-CFA-9796053 PRKCI phosphorylates NFE2L2 IEA Canis familiaris 456216 R-CFA-9796067 https://reactome.org/PathwayBrowser/#/R-CFA-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Canis familiaris 456216 R-CFA-9817397 https://reactome.org/PathwayBrowser/#/R-CFA-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Canis familiaris 456216 R-CFA-9818789 https://reactome.org/PathwayBrowser/#/R-CFA-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Canis familiaris 456216 R-CFA-9819106 https://reactome.org/PathwayBrowser/#/R-CFA-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Canis familiaris 456216 R-CFA-9823906 https://reactome.org/PathwayBrowser/#/R-CFA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Canis familiaris 456216 R-CFA-9824882 https://reactome.org/PathwayBrowser/#/R-CFA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Canis familiaris 456216 R-CFA-9824977 https://reactome.org/PathwayBrowser/#/R-CFA-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Canis familiaris 456216 R-CFA-9824994 https://reactome.org/PathwayBrowser/#/R-CFA-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Canis familiaris 456216 R-CFA-9824995 https://reactome.org/PathwayBrowser/#/R-CFA-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Canis familiaris 456216 R-CFA-9824999 https://reactome.org/PathwayBrowser/#/R-CFA-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Canis familiaris 456216 R-CFA-9825759 https://reactome.org/PathwayBrowser/#/R-CFA-9825759 MAPK-dependent phosphorylation of KARS IEA Canis familiaris 456216 R-CFA-982810 https://reactome.org/PathwayBrowser/#/R-CFA-982810 JAK2 phosphorylation IEA Canis familiaris 456216 R-CFA-983259 https://reactome.org/PathwayBrowser/#/R-CFA-983259 Kinesins move along microtubules consuming ATP IEA Canis familiaris 456216 R-CFA-9836159 https://reactome.org/PathwayBrowser/#/R-CFA-9836159 p-PKR dimer phosphorylates DHX9 IEA Canis familiaris 456216 R-CFA-9836184 https://reactome.org/PathwayBrowser/#/R-CFA-9836184 p-PKR dimer phosphorylates CDK1 IEA Canis familiaris 456216 R-CFA-9836322 https://reactome.org/PathwayBrowser/#/R-CFA-9836322 p-PKR dimer phosphorylates MKK6 IEA Canis familiaris 456216 R-CFA-9836362 https://reactome.org/PathwayBrowser/#/R-CFA-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Canis familiaris 456216 R-CFA-9836383 https://reactome.org/PathwayBrowser/#/R-CFA-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Canis familiaris 456216 R-CFA-9836404 https://reactome.org/PathwayBrowser/#/R-CFA-9836404 p-PKR dimer phosphorylates MAPT IEA Canis familiaris 456216 R-CFA-9836435 https://reactome.org/PathwayBrowser/#/R-CFA-9836435 p-PKR dimer phosphorylates SNCA IEA Canis familiaris 456216 R-CFA-9836515 https://reactome.org/PathwayBrowser/#/R-CFA-9836515 p-PKR dimer phosphorylates PTPN2 IEA Canis familiaris 456216 R-CFA-9836617 https://reactome.org/PathwayBrowser/#/R-CFA-9836617 p-PKR dimer phosphorylates SPHK1 IEA Canis familiaris 456216 R-CFA-9836664 https://reactome.org/PathwayBrowser/#/R-CFA-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Canis familiaris 456216 R-CFA-983703 https://reactome.org/PathwayBrowser/#/R-CFA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Canis familiaris 456216 R-CFA-983707 https://reactome.org/PathwayBrowser/#/R-CFA-983707 SYK autophosphorylates at the activated BCR IEA Canis familiaris 456216 R-CFA-9837333 https://reactome.org/PathwayBrowser/#/R-CFA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Canis familiaris 456216 R-CFA-9837337 https://reactome.org/PathwayBrowser/#/R-CFA-9837337 DCAKD phosphorylates DP-CoA IEA Canis familiaris 456216 R-CFA-9838004 https://reactome.org/PathwayBrowser/#/R-CFA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Canis familiaris 456216 R-CFA-9838081 https://reactome.org/PathwayBrowser/#/R-CFA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Canis familiaris 456216 R-CFA-9838289 https://reactome.org/PathwayBrowser/#/R-CFA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Canis familiaris 456216 R-CFA-9838321 https://reactome.org/PathwayBrowser/#/R-CFA-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Canis familiaris 456216 R-CFA-9839059 https://reactome.org/PathwayBrowser/#/R-CFA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Canis familiaris 456216 R-CFA-9839105 https://reactome.org/PathwayBrowser/#/R-CFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Canis familiaris 456216 R-CFA-9839113 https://reactome.org/PathwayBrowser/#/R-CFA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Canis familiaris 456216 R-CFA-9843721 https://reactome.org/PathwayBrowser/#/R-CFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Canis familiaris 456216 R-CFA-9851972 https://reactome.org/PathwayBrowser/#/R-CFA-9851972 PLK1 phosphorylates FIRRM at S43 IEA Canis familiaris 456216 R-CFA-9853369 https://reactome.org/PathwayBrowser/#/R-CFA-9853369 PLK1 phosphorylates FIRMM at S744 IEA Canis familiaris 456216 R-CFA-9861642 https://reactome.org/PathwayBrowser/#/R-CFA-9861642 NEK1 phosphorylates ME1 IEA Canis familiaris 456216 R-CFA-994137 https://reactome.org/PathwayBrowser/#/R-CFA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Canis familiaris 456216 R-CFA-994140 https://reactome.org/PathwayBrowser/#/R-CFA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Canis familiaris 456216 R-DDI-1008248 https://reactome.org/PathwayBrowser/#/R-DDI-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Dictyostelium discoideum 456216 R-DDI-109624 https://reactome.org/PathwayBrowser/#/R-DDI-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Dictyostelium discoideum 456216 R-DDI-109702 https://reactome.org/PathwayBrowser/#/R-DDI-109702 PDPK1 phosphorylates AKT2 IEA Dictyostelium discoideum 456216 R-DDI-109860 https://reactome.org/PathwayBrowser/#/R-DDI-109860 MAP2K1 phosphorylates MAPK3 IEA Dictyostelium discoideum 456216 R-DDI-109862 https://reactome.org/PathwayBrowser/#/R-DDI-109862 MAP2K2 phosphorylates MAPK1 IEA Dictyostelium discoideum 456216 R-DDI-109903 https://reactome.org/PathwayBrowser/#/R-DDI-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Dictyostelium discoideum 456216 R-DDI-110133 https://reactome.org/PathwayBrowser/#/R-DDI-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Dictyostelium discoideum 456216 R-DDI-110144 https://reactome.org/PathwayBrowser/#/R-DDI-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Dictyostelium discoideum 456216 R-DDI-110145 https://reactome.org/PathwayBrowser/#/R-DDI-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Dictyostelium discoideum 456216 R-DDI-111915 https://reactome.org/PathwayBrowser/#/R-DDI-111915 CAMK4 autophosphorylates IEA Dictyostelium discoideum 456216 R-DDI-114683 https://reactome.org/PathwayBrowser/#/R-DDI-114683 Phosphorylation of Platelet Sec-1 IEA Dictyostelium discoideum 456216 R-DDI-114684 https://reactome.org/PathwayBrowser/#/R-DDI-114684 Phosphorylation of Syntaxin-4 IEA Dictyostelium discoideum 456216 R-DDI-1247935 https://reactome.org/PathwayBrowser/#/R-DDI-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Dictyostelium discoideum 456216 R-DDI-1247960 https://reactome.org/PathwayBrowser/#/R-DDI-1247960 Activation of p38 MAPK IEA Dictyostelium discoideum 456216 R-DDI-1358791 https://reactome.org/PathwayBrowser/#/R-DDI-1358791 Phosphorylation of USP8 by P-AKT IEA Dictyostelium discoideum 456216 R-DDI-1369028 https://reactome.org/PathwayBrowser/#/R-DDI-1369028 ABCAs mediate lipid efflux IEA Dictyostelium discoideum 456216 R-DDI-1369052 https://reactome.org/PathwayBrowser/#/R-DDI-1369052 ABCAs mediate lipid influx IEA Dictyostelium discoideum 456216 R-DDI-1454916 https://reactome.org/PathwayBrowser/#/R-DDI-1454916 The ABCC family mediates organic anion transport IEA Dictyostelium discoideum 456216 R-DDI-1454928 https://reactome.org/PathwayBrowser/#/R-DDI-1454928 ABCG4 may mediate cholesterol efflux IEA Dictyostelium discoideum 456216 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-1467466 https://reactome.org/PathwayBrowser/#/R-DDI-1467466 ABCA4 mediates atRAL transport IEA Dictyostelium discoideum 456216 R-DDI-1483222 https://reactome.org/PathwayBrowser/#/R-DDI-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Dictyostelium discoideum 456216 R-DDI-156678 https://reactome.org/PathwayBrowser/#/R-DDI-156678 Activation of Cdc25C IEA Dictyostelium discoideum 456216 R-DDI-156682 https://reactome.org/PathwayBrowser/#/R-DDI-156682 PLK1 phosphorylates NUDC IEA Dictyostelium discoideum 456216 R-DDI-156699 https://reactome.org/PathwayBrowser/#/R-DDI-156699 Inactivation of Wee1 kinase IEA Dictyostelium discoideum 456216 R-DDI-162657 https://reactome.org/PathwayBrowser/#/R-DDI-162657 Inactivation of Myt1 kinase IEA Dictyostelium discoideum 456216 R-DDI-163215 https://reactome.org/PathwayBrowser/#/R-DDI-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Dictyostelium discoideum 456216 R-DDI-165162 https://reactome.org/PathwayBrowser/#/R-DDI-165162 Phosphorylation of TSC2 by PKB IEA Dictyostelium discoideum 456216 R-DDI-165692 https://reactome.org/PathwayBrowser/#/R-DDI-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Dictyostelium discoideum 456216 R-DDI-165718 https://reactome.org/PathwayBrowser/#/R-DDI-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Dictyostelium discoideum 456216 R-DDI-165726 https://reactome.org/PathwayBrowser/#/R-DDI-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Dictyostelium discoideum 456216 R-DDI-165758 https://reactome.org/PathwayBrowser/#/R-DDI-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Dictyostelium discoideum 456216 R-DDI-165766 https://reactome.org/PathwayBrowser/#/R-DDI-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Dictyostelium discoideum 456216 R-DDI-1675773 https://reactome.org/PathwayBrowser/#/R-DDI-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Dictyostelium discoideum 456216 R-DDI-1675776 https://reactome.org/PathwayBrowser/#/R-DDI-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Dictyostelium discoideum 456216 R-DDI-1675810 https://reactome.org/PathwayBrowser/#/R-DDI-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Dictyostelium discoideum 456216 R-DDI-1675813 https://reactome.org/PathwayBrowser/#/R-DDI-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Dictyostelium discoideum 456216 R-DDI-1675883 https://reactome.org/PathwayBrowser/#/R-DDI-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Dictyostelium discoideum 456216 R-DDI-1675928 https://reactome.org/PathwayBrowser/#/R-DDI-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Dictyostelium discoideum 456216 R-DDI-1675939 https://reactome.org/PathwayBrowser/#/R-DDI-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Dictyostelium discoideum 456216 R-DDI-1675961 https://reactome.org/PathwayBrowser/#/R-DDI-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Dictyostelium discoideum 456216 R-DDI-1676024 https://reactome.org/PathwayBrowser/#/R-DDI-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Dictyostelium discoideum 456216 R-DDI-1676048 https://reactome.org/PathwayBrowser/#/R-DDI-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Dictyostelium discoideum 456216 R-DDI-1676082 https://reactome.org/PathwayBrowser/#/R-DDI-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Dictyostelium discoideum 456216 R-DDI-1676109 https://reactome.org/PathwayBrowser/#/R-DDI-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Dictyostelium discoideum 456216 R-DDI-1676134 https://reactome.org/PathwayBrowser/#/R-DDI-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Dictyostelium discoideum 456216 R-DDI-1676145 https://reactome.org/PathwayBrowser/#/R-DDI-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Dictyostelium discoideum 456216 R-DDI-1676185 https://reactome.org/PathwayBrowser/#/R-DDI-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Dictyostelium discoideum 456216 R-DDI-1676206 https://reactome.org/PathwayBrowser/#/R-DDI-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Dictyostelium discoideum 456216 R-DDI-168162 https://reactome.org/PathwayBrowser/#/R-DDI-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Dictyostelium discoideum 456216 R-DDI-174079 https://reactome.org/PathwayBrowser/#/R-DDI-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Dictyostelium discoideum 456216 R-DDI-174394 https://reactome.org/PathwayBrowser/#/R-DDI-174394 GSS:Mg2+ dimer synthesizes GSH IEA Dictyostelium discoideum 456216 R-DDI-1855153 https://reactome.org/PathwayBrowser/#/R-DDI-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Dictyostelium discoideum 456216 R-DDI-1855157 https://reactome.org/PathwayBrowser/#/R-DDI-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 456216 R-DDI-1855158 https://reactome.org/PathwayBrowser/#/R-DDI-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 456216 R-DDI-1855162 https://reactome.org/PathwayBrowser/#/R-DDI-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Dictyostelium discoideum 456216 R-DDI-1855169 https://reactome.org/PathwayBrowser/#/R-DDI-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 456216 R-DDI-1855172 https://reactome.org/PathwayBrowser/#/R-DDI-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 456216 R-DDI-1855181 https://reactome.org/PathwayBrowser/#/R-DDI-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 456216 R-DDI-1855185 https://reactome.org/PathwayBrowser/#/R-DDI-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 456216 R-DDI-1855193 https://reactome.org/PathwayBrowser/#/R-DDI-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 456216 R-DDI-1855194 https://reactome.org/PathwayBrowser/#/R-DDI-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 456216 R-DDI-1855197 https://reactome.org/PathwayBrowser/#/R-DDI-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 456216 R-DDI-1855206 https://reactome.org/PathwayBrowser/#/R-DDI-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 456216 R-DDI-1855207 https://reactome.org/PathwayBrowser/#/R-DDI-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 456216 R-DDI-1855223 https://reactome.org/PathwayBrowser/#/R-DDI-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 456216 R-DDI-1855224 https://reactome.org/PathwayBrowser/#/R-DDI-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 456216 R-DDI-1855227 https://reactome.org/PathwayBrowser/#/R-DDI-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 456216 R-DDI-1855228 https://reactome.org/PathwayBrowser/#/R-DDI-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 456216 R-DDI-1855230 https://reactome.org/PathwayBrowser/#/R-DDI-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 456216 R-DDI-1855233 https://reactome.org/PathwayBrowser/#/R-DDI-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Dictyostelium discoideum 456216 R-DDI-191380 https://reactome.org/PathwayBrowser/#/R-DDI-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Dictyostelium discoideum 456216 R-DDI-191414 https://reactome.org/PathwayBrowser/#/R-DDI-191414 MVD decarboxylates MVA5PP to IPPP IEA Dictyostelium discoideum 456216 R-DDI-193362 https://reactome.org/PathwayBrowser/#/R-DDI-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-194153 https://reactome.org/PathwayBrowser/#/R-DDI-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-196773 https://reactome.org/PathwayBrowser/#/R-DDI-196773 COASY phosphorylates DP-CoA IEA Dictyostelium discoideum 456216 R-DDI-197198 https://reactome.org/PathwayBrowser/#/R-DDI-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Dictyostelium discoideum 456216 R-DDI-197958 https://reactome.org/PathwayBrowser/#/R-DDI-197958 FPGS-2 transforms THF to THFPG IEA Dictyostelium discoideum 456216 R-DDI-198314 https://reactome.org/PathwayBrowser/#/R-DDI-198314 DAG stimulates protein kinase C-delta IEA Dictyostelium discoideum 456216 R-DDI-198609 https://reactome.org/PathwayBrowser/#/R-DDI-198609 AKT phosphorylates TSC2, inhibiting it IEA Dictyostelium discoideum 456216 R-DDI-198640 https://reactome.org/PathwayBrowser/#/R-DDI-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Dictyostelium discoideum 456216 R-DDI-198669 https://reactome.org/PathwayBrowser/#/R-DDI-198669 p38MAPK phosphorylates MSK1 IEA Dictyostelium discoideum 456216 R-DDI-198746 https://reactome.org/PathwayBrowser/#/R-DDI-198746 ERK1/2/5 activate RSK1/2/3 IEA Dictyostelium discoideum 456216 R-DDI-198756 https://reactome.org/PathwayBrowser/#/R-DDI-198756 ERK1/2 phosphorylates MSK1 IEA Dictyostelium discoideum 456216 R-DDI-199839 https://reactome.org/PathwayBrowser/#/R-DDI-199839 AKT can phosphorylate RSK IEA Dictyostelium discoideum 456216 R-DDI-200423 https://reactome.org/PathwayBrowser/#/R-DDI-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Dictyostelium discoideum 456216 R-DDI-200555 https://reactome.org/PathwayBrowser/#/R-DDI-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Dictyostelium discoideum 456216 R-DDI-200681 https://reactome.org/PathwayBrowser/#/R-DDI-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Dictyostelium discoideum 456216 R-DDI-200682 https://reactome.org/PathwayBrowser/#/R-DDI-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Dictyostelium discoideum 456216 R-DDI-200711 https://reactome.org/PathwayBrowser/#/R-DDI-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Dictyostelium discoideum 456216 R-DDI-202111 https://reactome.org/PathwayBrowser/#/R-DDI-202111 AKT1 phosphorylates eNOS IEA Dictyostelium discoideum 456216 R-DDI-202222 https://reactome.org/PathwayBrowser/#/R-DDI-202222 Phosphorylation of PKC theta IEA Dictyostelium discoideum 456216 R-DDI-2029454 https://reactome.org/PathwayBrowser/#/R-DDI-2029454 Autophosphorylation of PAK1 IEA Dictyostelium discoideum 456216 R-DDI-2029460 https://reactome.org/PathwayBrowser/#/R-DDI-2029460 PAK1 phosphorylates LIMK1 IEA Dictyostelium discoideum 456216 R-DDI-2029469 https://reactome.org/PathwayBrowser/#/R-DDI-2029469 p-ERK phosphorylates WAVEs and ABI IEA Dictyostelium discoideum 456216 R-DDI-2029473 https://reactome.org/PathwayBrowser/#/R-DDI-2029473 Branching and elongation of mother and daughter filaments IEA Dictyostelium discoideum 456216 R-DDI-2046087 https://reactome.org/PathwayBrowser/#/R-DDI-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Dictyostelium discoideum 456216 R-DDI-2046093 https://reactome.org/PathwayBrowser/#/R-DDI-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Dictyostelium discoideum 456216 R-DDI-205136 https://reactome.org/PathwayBrowser/#/R-DDI-205136 GTP-bound RAC contributes to JNK activation IEA Dictyostelium discoideum 456216 R-DDI-2197690 https://reactome.org/PathwayBrowser/#/R-DDI-2197690 Detachment of WASP/WAVE IEA Dictyostelium discoideum 456216 R-DDI-2214351 https://reactome.org/PathwayBrowser/#/R-DDI-2214351 PLK1 phosphorylates GORASP1 IEA Dictyostelium discoideum 456216 R-DDI-2267372 https://reactome.org/PathwayBrowser/#/R-DDI-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Dictyostelium discoideum 456216 R-DDI-2294580 https://reactome.org/PathwayBrowser/#/R-DDI-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Dictyostelium discoideum 456216 R-DDI-2466068 https://reactome.org/PathwayBrowser/#/R-DDI-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Dictyostelium discoideum 456216 R-DDI-2529020 https://reactome.org/PathwayBrowser/#/R-DDI-2529020 CK2 phosphorylates condensin I subunits IEA Dictyostelium discoideum 456216 R-DDI-265783 https://reactome.org/PathwayBrowser/#/R-DDI-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-266082 https://reactome.org/PathwayBrowser/#/R-DDI-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Dictyostelium discoideum 456216 R-DDI-2730835 https://reactome.org/PathwayBrowser/#/R-DDI-2730835 Autophosphorylation of PKC-theta IEA Dictyostelium discoideum 456216 R-DDI-2730868 https://reactome.org/PathwayBrowser/#/R-DDI-2730868 Phosphorylation of MEK7 by MEKK1 IEA Dictyostelium discoideum 456216 R-DDI-2730896 https://reactome.org/PathwayBrowser/#/R-DDI-2730896 Phosphorylation of MEK4 by MEKK1 IEA Dictyostelium discoideum 456216 R-DDI-3095901 https://reactome.org/PathwayBrowser/#/R-DDI-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-3249379 https://reactome.org/PathwayBrowser/#/R-DDI-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Dictyostelium discoideum 456216 R-DDI-3371422 https://reactome.org/PathwayBrowser/#/R-DDI-3371422 ATP hydrolysis by HSP70 IEA Dictyostelium discoideum 456216 R-DDI-3371435 https://reactome.org/PathwayBrowser/#/R-DDI-3371435 Constitutive phosphorylation by GSK3 IEA Dictyostelium discoideum 456216 R-DDI-3371503 https://reactome.org/PathwayBrowser/#/R-DDI-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Dictyostelium discoideum 456216 R-DDI-3371531 https://reactome.org/PathwayBrowser/#/R-DDI-3371531 Constitutive phosphorylation by pERK1/2 IEA Dictyostelium discoideum 456216 R-DDI-349444 https://reactome.org/PathwayBrowser/#/R-DDI-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Dictyostelium discoideum 456216 R-DDI-377186 https://reactome.org/PathwayBrowser/#/R-DDI-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Dictyostelium discoideum 456216 R-DDI-3788705 https://reactome.org/PathwayBrowser/#/R-DDI-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Dictyostelium discoideum 456216 R-DDI-381091 https://reactome.org/PathwayBrowser/#/R-DDI-381091 IRE1 dimer autophosphorylates IEA Dictyostelium discoideum 456216 R-DDI-382560 https://reactome.org/PathwayBrowser/#/R-DDI-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Dictyostelium discoideum 456216 R-DDI-382575 https://reactome.org/PathwayBrowser/#/R-DDI-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Dictyostelium discoideum 456216 R-DDI-383190 https://reactome.org/PathwayBrowser/#/R-DDI-383190 HCO3- transport through ion channel IEA Dictyostelium discoideum 456216 R-DDI-391266 https://reactome.org/PathwayBrowser/#/R-DDI-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Dictyostelium discoideum 456216 R-DDI-392300 https://reactome.org/PathwayBrowser/#/R-DDI-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Dictyostelium discoideum 456216 R-DDI-3928620 https://reactome.org/PathwayBrowser/#/R-DDI-3928620 PAK1 autophosphorylates IEA Dictyostelium discoideum 456216 R-DDI-419644 https://reactome.org/PathwayBrowser/#/R-DDI-419644 Transphosphorylation of pLIMK1 IEA Dictyostelium discoideum 456216 R-DDI-426240 https://reactome.org/PathwayBrowser/#/R-DDI-426240 DAG kinase produces phosphatidic acid from DAG IEA Dictyostelium discoideum 456216 R-DDI-428273 https://reactome.org/PathwayBrowser/#/R-DDI-428273 SPHK1 phosphorylates sphingoid IEA Dictyostelium discoideum 456216 R-DDI-428941 https://reactome.org/PathwayBrowser/#/R-DDI-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Dictyostelium discoideum 456216 R-DDI-429157 https://reactome.org/PathwayBrowser/#/R-DDI-429157 ABCC4 accumulation of dense granule contents IEA Dictyostelium discoideum 456216 R-DDI-437162 https://reactome.org/PathwayBrowser/#/R-DDI-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Dictyostelium discoideum 456216 R-DDI-445072 https://reactome.org/PathwayBrowser/#/R-DDI-445072 Interaction of PAK1 with Rac1-GTP IEA Dictyostelium discoideum 456216 R-DDI-445079 https://reactome.org/PathwayBrowser/#/R-DDI-445079 Phosphorylation of L1 by ERK IEA Dictyostelium discoideum 456216 R-DDI-447074 https://reactome.org/PathwayBrowser/#/R-DDI-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Dictyostelium discoideum 456216 R-DDI-448955 https://reactome.org/PathwayBrowser/#/R-DDI-448955 Phosphorylation of MEF2 proteins by p38 IEA Dictyostelium discoideum 456216 R-DDI-450490 https://reactome.org/PathwayBrowser/#/R-DDI-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Dictyostelium discoideum 456216 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 456216 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 456216 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 456216 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 456216 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 456216 R-DDI-504054 https://reactome.org/PathwayBrowser/#/R-DDI-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Dictyostelium discoideum 456216 R-DDI-5082405 https://reactome.org/PathwayBrowser/#/R-DDI-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Dictyostelium discoideum 456216 R-DDI-508308 https://reactome.org/PathwayBrowser/#/R-DDI-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Dictyostelium discoideum 456216 R-DDI-5218805 https://reactome.org/PathwayBrowser/#/R-DDI-5218805 PKC autophosphorylates IEA Dictyostelium discoideum 456216 R-DDI-5218821 https://reactome.org/PathwayBrowser/#/R-DDI-5218821 PDK1 phosphorylates PKC IEA Dictyostelium discoideum 456216 R-DDI-5218823 https://reactome.org/PathwayBrowser/#/R-DDI-5218823 PKC phosphorylates sphingosine kinase 1 IEA Dictyostelium discoideum 456216 R-DDI-5223313 https://reactome.org/PathwayBrowser/#/R-DDI-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Dictyostelium discoideum 456216 R-DDI-5251955 https://reactome.org/PathwayBrowser/#/R-DDI-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Dictyostelium discoideum 456216 R-DDI-5251959 https://reactome.org/PathwayBrowser/#/R-DDI-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Dictyostelium discoideum 456216 R-DDI-5251989 https://reactome.org/PathwayBrowser/#/R-DDI-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Dictyostelium discoideum 456216 R-DDI-5252079 https://reactome.org/PathwayBrowser/#/R-DDI-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Dictyostelium discoideum 456216 R-DDI-5358513 https://reactome.org/PathwayBrowser/#/R-DDI-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Dictyostelium discoideum 456216 R-DDI-5358525 https://reactome.org/PathwayBrowser/#/R-DDI-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Dictyostelium discoideum 456216 R-DDI-5358912 https://reactome.org/PathwayBrowser/#/R-DDI-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Dictyostelium discoideum 456216 R-DDI-5444511 https://reactome.org/PathwayBrowser/#/R-DDI-5444511 Formation of MSH2:MSH3 Complex IEA Dictyostelium discoideum 456216 R-DDI-5444516 https://reactome.org/PathwayBrowser/#/R-DDI-5444516 Formation of MSH2:MSH6 Complex IEA Dictyostelium discoideum 456216 R-DDI-5618107 https://reactome.org/PathwayBrowser/#/R-DDI-5618107 ATP binding to HSP90 triggers conformation change IEA Dictyostelium discoideum 456216 R-DDI-5625784 https://reactome.org/PathwayBrowser/#/R-DDI-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Dictyostelium discoideum 456216 R-DDI-5627775 https://reactome.org/PathwayBrowser/#/R-DDI-5627775 Autophosphorylation of PAK1,2,3 IEA Dictyostelium discoideum 456216 R-DDI-5665868 https://reactome.org/PathwayBrowser/#/R-DDI-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Dictyostelium discoideum 456216 R-DDI-5668932 https://reactome.org/PathwayBrowser/#/R-DDI-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Dictyostelium discoideum 456216 R-DDI-5669250 https://reactome.org/PathwayBrowser/#/R-DDI-5669250 PAK1 phosphorylates FLNA IEA Dictyostelium discoideum 456216 R-DDI-5671749 https://reactome.org/PathwayBrowser/#/R-DDI-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Dictyostelium discoideum 456216 R-DDI-5672008 https://reactome.org/PathwayBrowser/#/R-DDI-5672008 Thr-180 of ULK1 is phosphorylated IEA Dictyostelium discoideum 456216 R-DDI-5672010 https://reactome.org/PathwayBrowser/#/R-DDI-5672010 Active MTORC1 phosphorylates ULK1 IEA Dictyostelium discoideum 456216 R-DDI-5672012 https://reactome.org/PathwayBrowser/#/R-DDI-5672012 Beclin-1 complex phosphorylates PtdIns IEA Dictyostelium discoideum 456216 R-DDI-5672828 https://reactome.org/PathwayBrowser/#/R-DDI-5672828 mTORC1 phosphorylates AKT1S1 IEA Dictyostelium discoideum 456216 R-DDI-5672948 https://reactome.org/PathwayBrowser/#/R-DDI-5672948 MARK3 phosphorylates KSR1 IEA Dictyostelium discoideum 456216 R-DDI-5673768 https://reactome.org/PathwayBrowser/#/R-DDI-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Dictyostelium discoideum 456216 R-DDI-5674130 https://reactome.org/PathwayBrowser/#/R-DDI-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Dictyostelium discoideum 456216 R-DDI-5674373 https://reactome.org/PathwayBrowser/#/R-DDI-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Dictyostelium discoideum 456216 R-DDI-5674496 https://reactome.org/PathwayBrowser/#/R-DDI-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Dictyostelium discoideum 456216 R-DDI-5675868 https://reactome.org/PathwayBrowser/#/R-DDI-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Dictyostelium discoideum 456216 R-DDI-5678706 https://reactome.org/PathwayBrowser/#/R-DDI-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-5678863 https://reactome.org/PathwayBrowser/#/R-DDI-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-5679041 https://reactome.org/PathwayBrowser/#/R-DDI-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-5679205 https://reactome.org/PathwayBrowser/#/R-DDI-5679205 ULK1 phosphorylates Beclin-1 IEA Dictyostelium discoideum 456216 R-DDI-5682026 https://reactome.org/PathwayBrowser/#/R-DDI-5682026 MRN bound to shortened telomeres activates ATM IEA Dictyostelium discoideum 456216 R-DDI-5682285 https://reactome.org/PathwayBrowser/#/R-DDI-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-5682983 https://reactome.org/PathwayBrowser/#/R-DDI-5682983 ATM phosphorylates WHSC1 IEA Dictyostelium discoideum 456216 R-DDI-5683425 https://reactome.org/PathwayBrowser/#/R-DDI-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Dictyostelium discoideum 456216 R-DDI-5683714 https://reactome.org/PathwayBrowser/#/R-DDI-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Dictyostelium discoideum 456216 R-DDI-5683792 https://reactome.org/PathwayBrowser/#/R-DDI-5683792 p-T68-CHEK2 autophosphorylates IEA Dictyostelium discoideum 456216 R-DDI-5687086 https://reactome.org/PathwayBrowser/#/R-DDI-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Dictyostelium discoideum 456216 R-DDI-5687183 https://reactome.org/PathwayBrowser/#/R-DDI-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Dictyostelium discoideum 456216 R-DDI-5690996 https://reactome.org/PathwayBrowser/#/R-DDI-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Dictyostelium discoideum 456216 R-DDI-5692462 https://reactome.org/PathwayBrowser/#/R-DDI-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Dictyostelium discoideum 456216 R-DDI-5692480 https://reactome.org/PathwayBrowser/#/R-DDI-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Dictyostelium discoideum 456216 R-DDI-5693536 https://reactome.org/PathwayBrowser/#/R-DDI-5693536 ATM phosphorylates MDC1 IEA Dictyostelium discoideum 456216 R-DDI-5693540 https://reactome.org/PathwayBrowser/#/R-DDI-5693540 MRN activates ATM IEA Dictyostelium discoideum 456216 R-DDI-5693549 https://reactome.org/PathwayBrowser/#/R-DDI-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Dictyostelium discoideum 456216 R-DDI-5693575 https://reactome.org/PathwayBrowser/#/R-DDI-5693575 DNA-PKcs autophosphorylates IEA Dictyostelium discoideum 456216 R-DDI-5693598 https://reactome.org/PathwayBrowser/#/R-DDI-5693598 ATM phosphorylates NBN IEA Dictyostelium discoideum 456216 R-DDI-5694441 https://reactome.org/PathwayBrowser/#/R-DDI-5694441 CSNK1D phosphorylates SEC23 IEA Dictyostelium discoideum 456216 R-DDI-5696021 https://reactome.org/PathwayBrowser/#/R-DDI-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Dictyostelium discoideum 456216 R-DDI-5696074 https://reactome.org/PathwayBrowser/#/R-DDI-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Dictyostelium discoideum 456216 R-DDI-5696839 https://reactome.org/PathwayBrowser/#/R-DDI-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Dictyostelium discoideum 456216 R-DDI-6782131 https://reactome.org/PathwayBrowser/#/R-DDI-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Dictyostelium discoideum 456216 R-DDI-6787540 https://reactome.org/PathwayBrowser/#/R-DDI-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Dictyostelium discoideum 456216 R-DDI-6788798 https://reactome.org/PathwayBrowser/#/R-DDI-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 456216 R-DDI-6788810 https://reactome.org/PathwayBrowser/#/R-DDI-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 456216 R-DDI-6795290 https://reactome.org/PathwayBrowser/#/R-DDI-6795290 TORC2 complex phosphorylates SGK1 IEA Dictyostelium discoideum 456216 R-DDI-6795473 https://reactome.org/PathwayBrowser/#/R-DDI-6795473 PDPK1 phosphorylates SGK1 IEA Dictyostelium discoideum 456216 R-DDI-6797606 https://reactome.org/PathwayBrowser/#/R-DDI-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Dictyostelium discoideum 456216 R-DDI-6798174 https://reactome.org/PathwayBrowser/#/R-DDI-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Dictyostelium discoideum 456216 R-DDI-6798372 https://reactome.org/PathwayBrowser/#/R-DDI-6798372 ATM phosphorylates DYRK2 IEA Dictyostelium discoideum 456216 R-DDI-6801456 https://reactome.org/PathwayBrowser/#/R-DDI-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Dictyostelium discoideum 456216 R-DDI-6802973 https://reactome.org/PathwayBrowser/#/R-DDI-6802973 PLK3 phosphorylates CDC25C IEA Dictyostelium discoideum 456216 R-DDI-6804266 https://reactome.org/PathwayBrowser/#/R-DDI-6804266 CHEK2 phosphorylates TTC5 IEA Dictyostelium discoideum 456216 R-DDI-6804276 https://reactome.org/PathwayBrowser/#/R-DDI-6804276 ATM phosphorylates TTC5 IEA Dictyostelium discoideum 456216 R-DDI-6805640 https://reactome.org/PathwayBrowser/#/R-DDI-6805640 AKT phosphorylates KAT6A IEA Dictyostelium discoideum 456216 R-DDI-6806877 https://reactome.org/PathwayBrowser/#/R-DDI-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Dictyostelium discoideum 456216 R-DDI-6806967 https://reactome.org/PathwayBrowser/#/R-DDI-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Dictyostelium discoideum 456216 R-DDI-6807868 https://reactome.org/PathwayBrowser/#/R-DDI-6807868 GBF1 stimulates ARF nucleotide exchange IEA Dictyostelium discoideum 456216 R-DDI-6810233 https://reactome.org/PathwayBrowser/#/R-DDI-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Dictyostelium discoideum 456216 R-DDI-6811522 https://reactome.org/PathwayBrowser/#/R-DDI-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Dictyostelium discoideum 456216 R-DDI-6814119 https://reactome.org/PathwayBrowser/#/R-DDI-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Dictyostelium discoideum 456216 R-DDI-6814120 https://reactome.org/PathwayBrowser/#/R-DDI-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Dictyostelium discoideum 456216 R-DDI-6814124 https://reactome.org/PathwayBrowser/#/R-DDI-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Dictyostelium discoideum 456216 R-DDI-6814678 https://reactome.org/PathwayBrowser/#/R-DDI-6814678 ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN IEA Dictyostelium discoideum 456216 R-DDI-69063 https://reactome.org/PathwayBrowser/#/R-DDI-69063 Loading of PCNA - Sliding Clamp Formation IEA Dictyostelium discoideum 456216 R-DDI-69608 https://reactome.org/PathwayBrowser/#/R-DDI-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Dictyostelium discoideum 456216 R-DDI-70333 https://reactome.org/PathwayBrowser/#/R-DDI-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Dictyostelium discoideum 456216 R-DDI-70349 https://reactome.org/PathwayBrowser/#/R-DDI-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 456216 R-DDI-70486 https://reactome.org/PathwayBrowser/#/R-DDI-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Dictyostelium discoideum 456216 R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Dictyostelium discoideum 456216 R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Dictyostelium discoideum 456216 R-DDI-70773 https://reactome.org/PathwayBrowser/#/R-DDI-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Dictyostelium discoideum 456216 R-DDI-70967 https://reactome.org/PathwayBrowser/#/R-DDI-70967 IDH3 complex decarboxylates isocitrate IEA Dictyostelium discoideum 456216 R-DDI-70997 https://reactome.org/PathwayBrowser/#/R-DDI-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Dictyostelium discoideum 456216 R-DDI-71031 https://reactome.org/PathwayBrowser/#/R-DDI-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Dictyostelium discoideum 456216 R-DDI-71401 https://reactome.org/PathwayBrowser/#/R-DDI-71401 OGDH dimer decarboxylates 2-OG IEA Dictyostelium discoideum 456216 R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 456216 R-DDI-71802 https://reactome.org/PathwayBrowser/#/R-DDI-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Dictyostelium discoideum 456216 R-DDI-71850 https://reactome.org/PathwayBrowser/#/R-DDI-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Dictyostelium discoideum 456216 R-DDI-72621 https://reactome.org/PathwayBrowser/#/R-DDI-72621 Ribosomal scanning IEA Dictyostelium discoideum 456216 R-DDI-73548 https://reactome.org/PathwayBrowser/#/R-DDI-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Dictyostelium discoideum 456216 R-DDI-73577 https://reactome.org/PathwayBrowser/#/R-DDI-73577 CAD hexamer transforms L-Gln to CAP IEA Dictyostelium discoideum 456216 R-DDI-73599 https://reactome.org/PathwayBrowser/#/R-DDI-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Dictyostelium discoideum 456216 R-DDI-73632 https://reactome.org/PathwayBrowser/#/R-DDI-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Dictyostelium discoideum 456216 R-DDI-73635 https://reactome.org/PathwayBrowser/#/R-DDI-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Dictyostelium discoideum 456216 R-DDI-73647 https://reactome.org/PathwayBrowser/#/R-DDI-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Dictyostelium discoideum 456216 R-DDI-73788 https://reactome.org/PathwayBrowser/#/R-DDI-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Dictyostelium discoideum 456216 R-DDI-73810 https://reactome.org/PathwayBrowser/#/R-DDI-73810 FGAM + ATP => AIR + ADP + Pi IEA Dictyostelium discoideum 456216 R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 456216 R-DDI-73814 https://reactome.org/PathwayBrowser/#/R-DDI-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Dictyostelium discoideum 456216 R-DDI-75125 https://reactome.org/PathwayBrowser/#/R-DDI-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Dictyostelium discoideum 456216 R-DDI-75126 https://reactome.org/PathwayBrowser/#/R-DDI-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Dictyostelium discoideum 456216 R-DDI-75809 https://reactome.org/PathwayBrowser/#/R-DDI-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Dictyostelium discoideum 456216 R-DDI-75848 https://reactome.org/PathwayBrowser/#/R-DDI-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Dictyostelium discoideum 456216 R-DDI-75851 https://reactome.org/PathwayBrowser/#/R-DDI-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 456216 R-DDI-75887 https://reactome.org/PathwayBrowser/#/R-DDI-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Dictyostelium discoideum 456216 R-DDI-75949 https://reactome.org/PathwayBrowser/#/R-DDI-75949 RNA Polymerase II Promoter Opening: First Transition IEA Dictyostelium discoideum 456216 R-DDI-77071 https://reactome.org/PathwayBrowser/#/R-DDI-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Dictyostelium discoideum 456216 R-DDI-8847638 https://reactome.org/PathwayBrowser/#/R-DDI-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Dictyostelium discoideum 456216 R-DDI-8848053 https://reactome.org/PathwayBrowser/#/R-DDI-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Dictyostelium discoideum 456216 R-DDI-8850945 https://reactome.org/PathwayBrowser/#/R-DDI-8850945 Casein kinase II phosphorylates PTEN IEA Dictyostelium discoideum 456216 R-DDI-8856813 https://reactome.org/PathwayBrowser/#/R-DDI-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Dictyostelium discoideum 456216 R-DDI-8867370 https://reactome.org/PathwayBrowser/#/R-DDI-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Dictyostelium discoideum 456216 R-DDI-8868066 https://reactome.org/PathwayBrowser/#/R-DDI-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Dictyostelium discoideum 456216 R-DDI-8868072 https://reactome.org/PathwayBrowser/#/R-DDI-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Dictyostelium discoideum 456216 R-DDI-8869606 https://reactome.org/PathwayBrowser/#/R-DDI-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 456216 R-DDI-8869607 https://reactome.org/PathwayBrowser/#/R-DDI-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 456216 R-DDI-8869627 https://reactome.org/PathwayBrowser/#/R-DDI-8869627 NMRK2 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 456216 R-DDI-8869633 https://reactome.org/PathwayBrowser/#/R-DDI-8869633 NMRK1 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 456216 R-DDI-8876446 https://reactome.org/PathwayBrowser/#/R-DDI-8876446 p-ULK1 phosphorylates DENND3 IEA Dictyostelium discoideum 456216 R-DDI-8876889 https://reactome.org/PathwayBrowser/#/R-DDI-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 456216 R-DDI-8877691 https://reactome.org/PathwayBrowser/#/R-DDI-8877691 MAP2K6 phosphorylates PIP4K2B IEA Dictyostelium discoideum 456216 R-DDI-8933446 https://reactome.org/PathwayBrowser/#/R-DDI-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Dictyostelium discoideum 456216 R-DDI-8944454 https://reactome.org/PathwayBrowser/#/R-DDI-8944454 mTORC1 phosphorylates MAF1 IEA Dictyostelium discoideum 456216 R-DDI-8948039 https://reactome.org/PathwayBrowser/#/R-DDI-8948039 FUNDC1 is phosphorylated by CK2 IEA Dictyostelium discoideum 456216 R-DDI-8948146 https://reactome.org/PathwayBrowser/#/R-DDI-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Dictyostelium discoideum 456216 R-DDI-8948757 https://reactome.org/PathwayBrowser/#/R-DDI-8948757 AKT phosphorylates MKRN1 IEA Dictyostelium discoideum 456216 R-DDI-8954327 https://reactome.org/PathwayBrowser/#/R-DDI-8954327 UCKL1 phosphorylates urindine, cytidine IEA Dictyostelium discoideum 456216 R-DDI-8955844 https://reactome.org/PathwayBrowser/#/R-DDI-8955844 RBKS phosphorylates ribose to R5P IEA Dictyostelium discoideum 456216 R-DDI-9008043 https://reactome.org/PathwayBrowser/#/R-DDI-9008043 MAPK8 phosphorylation IEA Dictyostelium discoideum 456216 R-DDI-9009072 https://reactome.org/PathwayBrowser/#/R-DDI-9009072 STAT3 phosphorylation IEA Dictyostelium discoideum 456216 R-DDI-9012319 https://reactome.org/PathwayBrowser/#/R-DDI-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Dictyostelium discoideum 456216 R-DDI-917693 https://reactome.org/PathwayBrowser/#/R-DDI-917693 ESCRT Disassembly IEA Dictyostelium discoideum 456216 R-DDI-917841 https://reactome.org/PathwayBrowser/#/R-DDI-917841 Acidification of Tf:TfR1 containing endosome IEA Dictyostelium discoideum 456216 R-DDI-917979 https://reactome.org/PathwayBrowser/#/R-DDI-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-927889 https://reactome.org/PathwayBrowser/#/R-DDI-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Dictyostelium discoideum 456216 R-DDI-936895 https://reactome.org/PathwayBrowser/#/R-DDI-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Dictyostelium discoideum 456216 R-DDI-939763 https://reactome.org/PathwayBrowser/#/R-DDI-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Dictyostelium discoideum 456216 R-DDI-947591 https://reactome.org/PathwayBrowser/#/R-DDI-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Dictyostelium discoideum 456216 R-DDI-9606884 https://reactome.org/PathwayBrowser/#/R-DDI-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Dictyostelium discoideum 456216 R-DDI-9612509 https://reactome.org/PathwayBrowser/#/R-DDI-9612509 SGK phosphorylates SRF IEA Dictyostelium discoideum 456216 R-DDI-9632858 https://reactome.org/PathwayBrowser/#/R-DDI-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Dictyostelium discoideum 456216 R-DDI-964958 https://reactome.org/PathwayBrowser/#/R-DDI-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Dictyostelium discoideum 456216 R-DDI-964962 https://reactome.org/PathwayBrowser/#/R-DDI-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Dictyostelium discoideum 456216 R-DDI-964970 https://reactome.org/PathwayBrowser/#/R-DDI-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Dictyostelium discoideum 456216 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 456216 R-DDI-9661417 https://reactome.org/PathwayBrowser/#/R-DDI-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-9668419 https://reactome.org/PathwayBrowser/#/R-DDI-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Dictyostelium discoideum 456216 R-DDI-9684118 https://reactome.org/PathwayBrowser/#/R-DDI-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Dictyostelium discoideum 456216 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 456216 R-DDI-9706399 https://reactome.org/PathwayBrowser/#/R-DDI-9706399 RHOBTB3 hydrolyzes ATP IEA Dictyostelium discoideum 456216 R-DDI-9748949 https://reactome.org/PathwayBrowser/#/R-DDI-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Dictyostelium discoideum 456216 R-DDI-9748963 https://reactome.org/PathwayBrowser/#/R-DDI-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Dictyostelium discoideum 456216 R-DDI-9748969 https://reactome.org/PathwayBrowser/#/R-DDI-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Dictyostelium discoideum 456216 R-DDI-9748999 https://reactome.org/PathwayBrowser/#/R-DDI-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Dictyostelium discoideum 456216 R-DDI-9750546 https://reactome.org/PathwayBrowser/#/R-DDI-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-9750656 https://reactome.org/PathwayBrowser/#/R-DDI-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Dictyostelium discoideum 456216 R-DDI-9753278 https://reactome.org/PathwayBrowser/#/R-DDI-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 456216 R-DDI-9753283 https://reactome.org/PathwayBrowser/#/R-DDI-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 456216 R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-9754974 https://reactome.org/PathwayBrowser/#/R-DDI-9754974 ADK phosphorylates RBV IEA Dictyostelium discoideum 456216 R-DDI-9755013 https://reactome.org/PathwayBrowser/#/R-DDI-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Dictyostelium discoideum 456216 R-DDI-9759206 https://reactome.org/PathwayBrowser/#/R-DDI-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Dictyostelium discoideum 456216 R-DDI-9759454 https://reactome.org/PathwayBrowser/#/R-DDI-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Dictyostelium discoideum 456216 R-DDI-9759461 https://reactome.org/PathwayBrowser/#/R-DDI-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Dictyostelium discoideum 456216 R-DDI-9794120 https://reactome.org/PathwayBrowser/#/R-DDI-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Dictyostelium discoideum 456216 R-DDI-9794572 https://reactome.org/PathwayBrowser/#/R-DDI-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Dictyostelium discoideum 456216 R-DDI-9825759 https://reactome.org/PathwayBrowser/#/R-DDI-9825759 MAPK-dependent phosphorylation of KARS IEA Dictyostelium discoideum 456216 R-DDI-9838004 https://reactome.org/PathwayBrowser/#/R-DDI-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Dictyostelium discoideum 456216 R-DDI-9838081 https://reactome.org/PathwayBrowser/#/R-DDI-9838081 LONP1 degrades mitochondrial matrix proteins IEA Dictyostelium discoideum 456216 R-DDI-9839105 https://reactome.org/PathwayBrowser/#/R-DDI-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Dictyostelium discoideum 456216 R-DDI-9839113 https://reactome.org/PathwayBrowser/#/R-DDI-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Dictyostelium discoideum 456216 R-DDI-9843721 https://reactome.org/PathwayBrowser/#/R-DDI-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Dictyostelium discoideum 456216 R-DDI-994137 https://reactome.org/PathwayBrowser/#/R-DDI-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Dictyostelium discoideum 456216 R-DDI-994140 https://reactome.org/PathwayBrowser/#/R-DDI-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Dictyostelium discoideum 456216 R-DME-1008248 https://reactome.org/PathwayBrowser/#/R-DME-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Drosophila melanogaster 456216 R-DME-109624 https://reactome.org/PathwayBrowser/#/R-DME-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Drosophila melanogaster 456216 R-DME-109699 https://reactome.org/PathwayBrowser/#/R-DME-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-109702 https://reactome.org/PathwayBrowser/#/R-DME-109702 PDPK1 phosphorylates AKT2 IEA Drosophila melanogaster 456216 R-DME-109759 https://reactome.org/PathwayBrowser/#/R-DME-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Drosophila melanogaster 456216 R-DME-109822 https://reactome.org/PathwayBrowser/#/R-DME-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Drosophila melanogaster 456216 R-DME-109823 https://reactome.org/PathwayBrowser/#/R-DME-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Drosophila melanogaster 456216 R-DME-109860 https://reactome.org/PathwayBrowser/#/R-DME-109860 MAP2K1 phosphorylates MAPK3 IEA Drosophila melanogaster 456216 R-DME-109862 https://reactome.org/PathwayBrowser/#/R-DME-109862 MAP2K2 phosphorylates MAPK1 IEA Drosophila melanogaster 456216 R-DME-109903 https://reactome.org/PathwayBrowser/#/R-DME-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Drosophila melanogaster 456216 R-DME-110133 https://reactome.org/PathwayBrowser/#/R-DME-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Drosophila melanogaster 456216 R-DME-110137 https://reactome.org/PathwayBrowser/#/R-DME-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Drosophila melanogaster 456216 R-DME-110138 https://reactome.org/PathwayBrowser/#/R-DME-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 456216 R-DME-110141 https://reactome.org/PathwayBrowser/#/R-DME-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Drosophila melanogaster 456216 R-DME-110144 https://reactome.org/PathwayBrowser/#/R-DME-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Drosophila melanogaster 456216 R-DME-110145 https://reactome.org/PathwayBrowser/#/R-DME-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Drosophila melanogaster 456216 R-DME-110440 https://reactome.org/PathwayBrowser/#/R-DME-110440 Autophosphorylation of DINR TAS Drosophila melanogaster 456216 R-DME-110453 https://reactome.org/PathwayBrowser/#/R-DME-110453 Phosphorylation of PIP2 to PIP3 by Dp110 TAS Drosophila melanogaster 456216 R-DME-110468 https://reactome.org/PathwayBrowser/#/R-DME-110468 Activation of DAkt1 by DPDK1 TAS Drosophila melanogaster 456216 R-DME-110475 https://reactome.org/PathwayBrowser/#/R-DME-110475 DAkt1-mediated phosphorylation inactivates DFOXO TAS Drosophila melanogaster 456216 R-DME-110498 https://reactome.org/PathwayBrowser/#/R-DME-110498 DTOR is positively regulated by DRheb-GTP TAS Drosophila melanogaster 456216 R-DME-110506 https://reactome.org/PathwayBrowser/#/R-DME-110506 Activated DTOR phosphorylates DS6K TAS Drosophila melanogaster 456216 R-DME-110518 https://reactome.org/PathwayBrowser/#/R-DME-110518 Activated DTOR also phosphorylates D4EBP TAS Drosophila melanogaster 456216 R-DME-111915 https://reactome.org/PathwayBrowser/#/R-DME-111915 CAMK4 autophosphorylates IEA Drosophila melanogaster 456216 R-DME-111970 https://reactome.org/PathwayBrowser/#/R-DME-111970 PKC phosphorylates GRK2 IEA Drosophila melanogaster 456216 R-DME-112342 https://reactome.org/PathwayBrowser/#/R-DME-112342 Inactivation of MAP2K1 by CDK1 IEA Drosophila melanogaster 456216 R-DME-114252 https://reactome.org/PathwayBrowser/#/R-DME-114252 Cleavage of Procaspase-3 by the apoptosome IEA Drosophila melanogaster 456216 R-DME-114254 https://reactome.org/PathwayBrowser/#/R-DME-114254 CYCS binds to APAF1 IEA Drosophila melanogaster 456216 R-DME-114259 https://reactome.org/PathwayBrowser/#/R-DME-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Drosophila melanogaster 456216 R-DME-114683 https://reactome.org/PathwayBrowser/#/R-DME-114683 Phosphorylation of Platelet Sec-1 IEA Drosophila melanogaster 456216 R-DME-114684 https://reactome.org/PathwayBrowser/#/R-DME-114684 Phosphorylation of Syntaxin-4 IEA Drosophila melanogaster 456216 R-DME-1168638 https://reactome.org/PathwayBrowser/#/R-DME-1168638 Activated IKK phosphorylates I-kappaB IEA Drosophila melanogaster 456216 R-DME-1181149 https://reactome.org/PathwayBrowser/#/R-DME-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Drosophila melanogaster 456216 R-DME-1226094 https://reactome.org/PathwayBrowser/#/R-DME-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Drosophila melanogaster 456216 R-DME-1226095 https://reactome.org/PathwayBrowser/#/R-DME-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Drosophila melanogaster 456216 R-DME-1247935 https://reactome.org/PathwayBrowser/#/R-DME-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Drosophila melanogaster 456216 R-DME-1247960 https://reactome.org/PathwayBrowser/#/R-DME-1247960 Activation of p38 MAPK IEA Drosophila melanogaster 456216 R-DME-1250195 https://reactome.org/PathwayBrowser/#/R-DME-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Drosophila melanogaster 456216 R-DME-1250315 https://reactome.org/PathwayBrowser/#/R-DME-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Drosophila melanogaster 456216 R-DME-1250348 https://reactome.org/PathwayBrowser/#/R-DME-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Drosophila melanogaster 456216 R-DME-1250370 https://reactome.org/PathwayBrowser/#/R-DME-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Drosophila melanogaster 456216 R-DME-1250462 https://reactome.org/PathwayBrowser/#/R-DME-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Drosophila melanogaster 456216 R-DME-1295609 https://reactome.org/PathwayBrowser/#/R-DME-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Drosophila melanogaster 456216 R-DME-1306957 https://reactome.org/PathwayBrowser/#/R-DME-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Drosophila melanogaster 456216 R-DME-1306979 https://reactome.org/PathwayBrowser/#/R-DME-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Drosophila melanogaster 456216 R-DME-1307963 https://reactome.org/PathwayBrowser/#/R-DME-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Drosophila melanogaster 456216 R-DME-1358791 https://reactome.org/PathwayBrowser/#/R-DME-1358791 Phosphorylation of USP8 by P-AKT IEA Drosophila melanogaster 456216 R-DME-1362270 https://reactome.org/PathwayBrowser/#/R-DME-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Drosophila melanogaster 456216 R-DME-1369065 https://reactome.org/PathwayBrowser/#/R-DME-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Drosophila melanogaster 456216 R-DME-1433418 https://reactome.org/PathwayBrowser/#/R-DME-1433418 Phosphorylation of JAK2 IEA Drosophila melanogaster 456216 R-DME-1433506 https://reactome.org/PathwayBrowser/#/R-DME-1433506 Phosphorylation of APS IEA Drosophila melanogaster 456216 R-DME-1433508 https://reactome.org/PathwayBrowser/#/R-DME-1433508 PKC alpha interacts with and phosphorylates KIT IEA Drosophila melanogaster 456216 R-DME-1454916 https://reactome.org/PathwayBrowser/#/R-DME-1454916 The ABCC family mediates organic anion transport IEA Drosophila melanogaster 456216 R-DME-1454928 https://reactome.org/PathwayBrowser/#/R-DME-1454928 ABCG4 may mediate cholesterol efflux IEA Drosophila melanogaster 456216 R-DME-1467466 https://reactome.org/PathwayBrowser/#/R-DME-1467466 ABCA4 mediates atRAL transport IEA Drosophila melanogaster 456216 R-DME-1470009 https://reactome.org/PathwayBrowser/#/R-DME-1470009 Phosphorylation of STATs IEA Drosophila melanogaster 456216 R-DME-1475422 https://reactome.org/PathwayBrowser/#/R-DME-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Drosophila melanogaster 456216 R-DME-1483004 https://reactome.org/PathwayBrowser/#/R-DME-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Drosophila melanogaster 456216 R-DME-1483222 https://reactome.org/PathwayBrowser/#/R-DME-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Drosophila melanogaster 456216 R-DME-1497853 https://reactome.org/PathwayBrowser/#/R-DME-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Drosophila melanogaster 456216 R-DME-1524186 https://reactome.org/PathwayBrowser/#/R-DME-1524186 Phosphorylation of PLCgamma by PDGFR IEA Drosophila melanogaster 456216 R-DME-1549526 https://reactome.org/PathwayBrowser/#/R-DME-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Drosophila melanogaster 456216 R-DME-156673 https://reactome.org/PathwayBrowser/#/R-DME-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Drosophila melanogaster 456216 R-DME-156678 https://reactome.org/PathwayBrowser/#/R-DME-156678 Activation of Cdc25C IEA Drosophila melanogaster 456216 R-DME-156682 https://reactome.org/PathwayBrowser/#/R-DME-156682 PLK1 phosphorylates NUDC IEA Drosophila melanogaster 456216 R-DME-156699 https://reactome.org/PathwayBrowser/#/R-DME-156699 Inactivation of Wee1 kinase IEA Drosophila melanogaster 456216 R-DME-156723 https://reactome.org/PathwayBrowser/#/R-DME-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Drosophila melanogaster 456216 R-DME-159101 https://reactome.org/PathwayBrowser/#/R-DME-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Drosophila melanogaster 456216 R-DME-162657 https://reactome.org/PathwayBrowser/#/R-DME-162657 Inactivation of Myt1 kinase IEA Drosophila melanogaster 456216 R-DME-163010 https://reactome.org/PathwayBrowser/#/R-DME-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Drosophila melanogaster 456216 R-DME-163215 https://reactome.org/PathwayBrowser/#/R-DME-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Drosophila melanogaster 456216 R-DME-1632857 https://reactome.org/PathwayBrowser/#/R-DME-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Drosophila melanogaster 456216 R-DME-1638845 https://reactome.org/PathwayBrowser/#/R-DME-1638845 CERK phosphorylates CERA to form C1P IEA Drosophila melanogaster 456216 R-DME-164696 https://reactome.org/PathwayBrowser/#/R-DME-164696 Chico is phosphorylated TAS Drosophila melanogaster 456216 R-DME-164832 https://reactome.org/PathwayBrowser/#/R-DME-164832 ATPase synthesizes ATP IEA Drosophila melanogaster 456216 R-DME-164840 https://reactome.org/PathwayBrowser/#/R-DME-164840 ADP and Pi bind to ATPase IEA Drosophila melanogaster 456216 R-DME-165162 https://reactome.org/PathwayBrowser/#/R-DME-165162 Phosphorylation of TSC2 by PKB IEA Drosophila melanogaster 456216 R-DME-165182 https://reactome.org/PathwayBrowser/#/R-DME-165182 Phosphorylation of complexed TSC2 by PKB IEA Drosophila melanogaster 456216 R-DME-165692 https://reactome.org/PathwayBrowser/#/R-DME-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Drosophila melanogaster 456216 R-DME-165718 https://reactome.org/PathwayBrowser/#/R-DME-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Drosophila melanogaster 456216 R-DME-165726 https://reactome.org/PathwayBrowser/#/R-DME-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Drosophila melanogaster 456216 R-DME-165766 https://reactome.org/PathwayBrowser/#/R-DME-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Drosophila melanogaster 456216 R-DME-1675773 https://reactome.org/PathwayBrowser/#/R-DME-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Drosophila melanogaster 456216 R-DME-1675776 https://reactome.org/PathwayBrowser/#/R-DME-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Drosophila melanogaster 456216 R-DME-1675780 https://reactome.org/PathwayBrowser/#/R-DME-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Drosophila melanogaster 456216 R-DME-1675810 https://reactome.org/PathwayBrowser/#/R-DME-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Drosophila melanogaster 456216 R-DME-1675813 https://reactome.org/PathwayBrowser/#/R-DME-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Drosophila melanogaster 456216 R-DME-1675883 https://reactome.org/PathwayBrowser/#/R-DME-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Drosophila melanogaster 456216 R-DME-1675928 https://reactome.org/PathwayBrowser/#/R-DME-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Drosophila melanogaster 456216 R-DME-1675939 https://reactome.org/PathwayBrowser/#/R-DME-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Drosophila melanogaster 456216 R-DME-1675961 https://reactome.org/PathwayBrowser/#/R-DME-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Drosophila melanogaster 456216 R-DME-1675974 https://reactome.org/PathwayBrowser/#/R-DME-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Drosophila melanogaster 456216 R-DME-1676024 https://reactome.org/PathwayBrowser/#/R-DME-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Drosophila melanogaster 456216 R-DME-1676048 https://reactome.org/PathwayBrowser/#/R-DME-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Drosophila melanogaster 456216 R-DME-1676082 https://reactome.org/PathwayBrowser/#/R-DME-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Drosophila melanogaster 456216 R-DME-1676109 https://reactome.org/PathwayBrowser/#/R-DME-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Drosophila melanogaster 456216 R-DME-1676134 https://reactome.org/PathwayBrowser/#/R-DME-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Drosophila melanogaster 456216 R-DME-1676145 https://reactome.org/PathwayBrowser/#/R-DME-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Drosophila melanogaster 456216 R-DME-1676185 https://reactome.org/PathwayBrowser/#/R-DME-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Drosophila melanogaster 456216 R-DME-1676206 https://reactome.org/PathwayBrowser/#/R-DME-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Drosophila melanogaster 456216 R-DME-168053 https://reactome.org/PathwayBrowser/#/R-DME-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Drosophila melanogaster 456216 R-DME-168136 https://reactome.org/PathwayBrowser/#/R-DME-168136 Activated JNKs phosphorylate c-JUN IEA Drosophila melanogaster 456216 R-DME-168140 https://reactome.org/PathwayBrowser/#/R-DME-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Drosophila melanogaster 456216 R-DME-168162 https://reactome.org/PathwayBrowser/#/R-DME-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Drosophila melanogaster 456216 R-DME-169827 https://reactome.org/PathwayBrowser/#/R-DME-169827 DPDK1 phosphorylates and activates DS6K TAS Drosophila melanogaster 456216 R-DME-169828 https://reactome.org/PathwayBrowser/#/R-DME-169828 Activated DAkt1 phosphorylates TSC2 which inhibits the TSC1/2 complex TAS Drosophila melanogaster 456216 R-DME-170026 https://reactome.org/PathwayBrowser/#/R-DME-170026 Protons are translocated from the intermembrane space to the matrix IEA Drosophila melanogaster 456216 R-DME-170055 https://reactome.org/PathwayBrowser/#/R-DME-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Drosophila melanogaster 456216 R-DME-170070 https://reactome.org/PathwayBrowser/#/R-DME-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Drosophila melanogaster 456216 R-DME-170076 https://reactome.org/PathwayBrowser/#/R-DME-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Drosophila melanogaster 456216 R-DME-170087 https://reactome.org/PathwayBrowser/#/R-DME-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Drosophila melanogaster 456216 R-DME-170126 https://reactome.org/PathwayBrowser/#/R-DME-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Drosophila melanogaster 456216 R-DME-170843 https://reactome.org/PathwayBrowser/#/R-DME-170843 TGFBR2 phosphorylates TGFBR1 IEA Drosophila melanogaster 456216 R-DME-170868 https://reactome.org/PathwayBrowser/#/R-DME-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Drosophila melanogaster 456216 R-DME-174079 https://reactome.org/PathwayBrowser/#/R-DME-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Drosophila melanogaster 456216 R-DME-174122 https://reactome.org/PathwayBrowser/#/R-DME-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Drosophila melanogaster 456216 R-DME-174164 https://reactome.org/PathwayBrowser/#/R-DME-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Drosophila melanogaster 456216 R-DME-174174 https://reactome.org/PathwayBrowser/#/R-DME-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Drosophila melanogaster 456216 R-DME-174251 https://reactome.org/PathwayBrowser/#/R-DME-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Drosophila melanogaster 456216 R-DME-174367 https://reactome.org/PathwayBrowser/#/R-DME-174367 GCL ligates L-Glu to L-Cys IEA Drosophila melanogaster 456216 R-DME-174389 https://reactome.org/PathwayBrowser/#/R-DME-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Drosophila melanogaster 456216 R-DME-174394 https://reactome.org/PathwayBrowser/#/R-DME-174394 GSS:Mg2+ dimer synthesizes GSH IEA Drosophila melanogaster 456216 R-DME-176116 https://reactome.org/PathwayBrowser/#/R-DME-176116 Recruitment and activation of Chk1 IEA Drosophila melanogaster 456216 R-DME-176298 https://reactome.org/PathwayBrowser/#/R-DME-176298 Activation of claspin IEA Drosophila melanogaster 456216 R-DME-177284 https://reactome.org/PathwayBrowser/#/R-DME-177284 PKA phosphorylates PDE4B IEA Drosophila melanogaster 456216 R-DME-177930 https://reactome.org/PathwayBrowser/#/R-DME-177930 GAB1 phosphorylation by EGFR kinase IEA Drosophila melanogaster 456216 R-DME-177933 https://reactome.org/PathwayBrowser/#/R-DME-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Drosophila melanogaster 456216 R-DME-177934 https://reactome.org/PathwayBrowser/#/R-DME-177934 EGFR autophosphorylation IEA Drosophila melanogaster 456216 R-DME-177937 https://reactome.org/PathwayBrowser/#/R-DME-177937 Phosphorylation of EGFR by SRC kinase IEA Drosophila melanogaster 456216 R-DME-177939 https://reactome.org/PathwayBrowser/#/R-DME-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Drosophila melanogaster 456216 R-DME-182969 https://reactome.org/PathwayBrowser/#/R-DME-182969 Phosphorylation of CBL (EGFR:CBL) IEA Drosophila melanogaster 456216 R-DME-183058 https://reactome.org/PathwayBrowser/#/R-DME-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Drosophila melanogaster 456216 R-DME-1855153 https://reactome.org/PathwayBrowser/#/R-DME-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Drosophila melanogaster 456216 R-DME-1855157 https://reactome.org/PathwayBrowser/#/R-DME-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 456216 R-DME-1855158 https://reactome.org/PathwayBrowser/#/R-DME-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 456216 R-DME-1855181 https://reactome.org/PathwayBrowser/#/R-DME-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 456216 R-DME-1855182 https://reactome.org/PathwayBrowser/#/R-DME-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Drosophila melanogaster 456216 R-DME-1855185 https://reactome.org/PathwayBrowser/#/R-DME-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 456216 R-DME-1855193 https://reactome.org/PathwayBrowser/#/R-DME-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 456216 R-DME-1855194 https://reactome.org/PathwayBrowser/#/R-DME-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 456216 R-DME-1855206 https://reactome.org/PathwayBrowser/#/R-DME-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 456216 R-DME-1855207 https://reactome.org/PathwayBrowser/#/R-DME-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 456216 R-DME-1855216 https://reactome.org/PathwayBrowser/#/R-DME-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Drosophila melanogaster 456216 R-DME-1855223 https://reactome.org/PathwayBrowser/#/R-DME-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 456216 R-DME-1855224 https://reactome.org/PathwayBrowser/#/R-DME-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 456216 R-DME-1855227 https://reactome.org/PathwayBrowser/#/R-DME-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 456216 R-DME-1855228 https://reactome.org/PathwayBrowser/#/R-DME-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 456216 R-DME-1855230 https://reactome.org/PathwayBrowser/#/R-DME-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 456216 R-DME-1855233 https://reactome.org/PathwayBrowser/#/R-DME-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Drosophila melanogaster 456216 R-DME-186786 https://reactome.org/PathwayBrowser/#/R-DME-186786 Autophosphorylation of PDGF beta receptors IEA Drosophila melanogaster 456216 R-DME-186800 https://reactome.org/PathwayBrowser/#/R-DME-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-187520 https://reactome.org/PathwayBrowser/#/R-DME-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Drosophila melanogaster 456216 R-DME-187688 https://reactome.org/PathwayBrowser/#/R-DME-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Drosophila melanogaster 456216 R-DME-187916 https://reactome.org/PathwayBrowser/#/R-DME-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Drosophila melanogaster 456216 R-DME-187948 https://reactome.org/PathwayBrowser/#/R-DME-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Drosophila melanogaster 456216 R-DME-187949 https://reactome.org/PathwayBrowser/#/R-DME-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Drosophila melanogaster 456216 R-DME-187959 https://reactome.org/PathwayBrowser/#/R-DME-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Drosophila melanogaster 456216 R-DME-188350 https://reactome.org/PathwayBrowser/#/R-DME-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Drosophila melanogaster 456216 R-DME-190326 https://reactome.org/PathwayBrowser/#/R-DME-190326 Autocatalytic phosphorylation of FGFR4 IEA Drosophila melanogaster 456216 R-DME-190385 https://reactome.org/PathwayBrowser/#/R-DME-190385 Autocatalytic phosphorylation of FGFR3b IEA Drosophila melanogaster 456216 R-DME-190388 https://reactome.org/PathwayBrowser/#/R-DME-190388 Autocatalytic phosphorylation of FGFR3c IEA Drosophila melanogaster 456216 R-DME-190408 https://reactome.org/PathwayBrowser/#/R-DME-190408 Autocatalytic phosphorylation of FGFR2b IEA Drosophila melanogaster 456216 R-DME-190413 https://reactome.org/PathwayBrowser/#/R-DME-190413 Autocatalytic phosphorylation of FGFR2c IEA Drosophila melanogaster 456216 R-DME-190427 https://reactome.org/PathwayBrowser/#/R-DME-190427 Autocatalytic phosphorylation of FGFR1b IEA Drosophila melanogaster 456216 R-DME-190429 https://reactome.org/PathwayBrowser/#/R-DME-190429 Autocatalytic phosphorylation of FGFR1c IEA Drosophila melanogaster 456216 R-DME-191062 https://reactome.org/PathwayBrowser/#/R-DME-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Drosophila melanogaster 456216 R-DME-191380 https://reactome.org/PathwayBrowser/#/R-DME-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Drosophila melanogaster 456216 R-DME-191414 https://reactome.org/PathwayBrowser/#/R-DME-191414 MVD decarboxylates MVA5PP to IPPP IEA Drosophila melanogaster 456216 R-DME-191422 https://reactome.org/PathwayBrowser/#/R-DME-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Drosophila melanogaster 456216 R-DME-194153 https://reactome.org/PathwayBrowser/#/R-DME-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Drosophila melanogaster 456216 R-DME-195275 https://reactome.org/PathwayBrowser/#/R-DME-195275 Phosphorylation of APC component of the destruction complex IEA Drosophila melanogaster 456216 R-DME-195283 https://reactome.org/PathwayBrowser/#/R-DME-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Drosophila melanogaster 456216 R-DME-195287 https://reactome.org/PathwayBrowser/#/R-DME-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Drosophila melanogaster 456216 R-DME-195300 https://reactome.org/PathwayBrowser/#/R-DME-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Drosophila melanogaster 456216 R-DME-195318 https://reactome.org/PathwayBrowser/#/R-DME-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Drosophila melanogaster 456216 R-DME-1963581 https://reactome.org/PathwayBrowser/#/R-DME-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Drosophila melanogaster 456216 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 456216 R-DME-1963586 https://reactome.org/PathwayBrowser/#/R-DME-1963586 SRC family kinases phosphorylate ERBB2 IEA Drosophila melanogaster 456216 R-DME-196857 https://reactome.org/PathwayBrowser/#/R-DME-196857 PANK2 phosphorylates PanK IEA Drosophila melanogaster 456216 R-DME-196964 https://reactome.org/PathwayBrowser/#/R-DME-196964 RFK:Mg2+ phosphorylates RIB IEA Drosophila melanogaster 456216 R-DME-197198 https://reactome.org/PathwayBrowser/#/R-DME-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 456216 R-DME-197958 https://reactome.org/PathwayBrowser/#/R-DME-197958 FPGS-2 transforms THF to THFPG IEA Drosophila melanogaster 456216 R-DME-198266 https://reactome.org/PathwayBrowser/#/R-DME-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Drosophila melanogaster 456216 R-DME-198314 https://reactome.org/PathwayBrowser/#/R-DME-198314 DAG stimulates protein kinase C-delta IEA Drosophila melanogaster 456216 R-DME-198609 https://reactome.org/PathwayBrowser/#/R-DME-198609 AKT phosphorylates TSC2, inhibiting it IEA Drosophila melanogaster 456216 R-DME-198611 https://reactome.org/PathwayBrowser/#/R-DME-198611 AKT phosphorylates IKKalpha IEA Drosophila melanogaster 456216 R-DME-198613 https://reactome.org/PathwayBrowser/#/R-DME-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Drosophila melanogaster 456216 R-DME-198621 https://reactome.org/PathwayBrowser/#/R-DME-198621 AKT phosphorylates caspase-9 IEA Drosophila melanogaster 456216 R-DME-198640 https://reactome.org/PathwayBrowser/#/R-DME-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Drosophila melanogaster 456216 R-DME-198669 https://reactome.org/PathwayBrowser/#/R-DME-198669 p38MAPK phosphorylates MSK1 IEA Drosophila melanogaster 456216 R-DME-198746 https://reactome.org/PathwayBrowser/#/R-DME-198746 ERK1/2/5 activate RSK1/2/3 IEA Drosophila melanogaster 456216 R-DME-198756 https://reactome.org/PathwayBrowser/#/R-DME-198756 ERK1/2 phosphorylates MSK1 IEA Drosophila melanogaster 456216 R-DME-199203 https://reactome.org/PathwayBrowser/#/R-DME-199203 PANK1/3 phosphorylate PanK IEA Drosophila melanogaster 456216 R-DME-199298 https://reactome.org/PathwayBrowser/#/R-DME-199298 AKT phosphorylates CREB1 IEA Drosophila melanogaster 456216 R-DME-199299 https://reactome.org/PathwayBrowser/#/R-DME-199299 AKT phosphorylates FOXO transcription factors IEA Drosophila melanogaster 456216 R-DME-199839 https://reactome.org/PathwayBrowser/#/R-DME-199839 AKT can phosphorylate RSK IEA Drosophila melanogaster 456216 R-DME-199863 https://reactome.org/PathwayBrowser/#/R-DME-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Drosophila melanogaster 456216 R-DME-199895 https://reactome.org/PathwayBrowser/#/R-DME-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Drosophila melanogaster 456216 R-DME-199910 https://reactome.org/PathwayBrowser/#/R-DME-199910 MSK1 activates ATF1 IEA Drosophila melanogaster 456216 R-DME-199917 https://reactome.org/PathwayBrowser/#/R-DME-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Drosophila melanogaster 456216 R-DME-199935 https://reactome.org/PathwayBrowser/#/R-DME-199935 MSK1 activates CREB IEA Drosophila melanogaster 456216 R-DME-200143 https://reactome.org/PathwayBrowser/#/R-DME-200143 AKT phosphorylates AKT1S1 (PRAS40) IEA Drosophila melanogaster 456216 R-DME-200423 https://reactome.org/PathwayBrowser/#/R-DME-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Drosophila melanogaster 456216 R-DME-200555 https://reactome.org/PathwayBrowser/#/R-DME-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Drosophila melanogaster 456216 R-DME-200681 https://reactome.org/PathwayBrowser/#/R-DME-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Drosophila melanogaster 456216 R-DME-200682 https://reactome.org/PathwayBrowser/#/R-DME-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Drosophila melanogaster 456216 R-DME-200711 https://reactome.org/PathwayBrowser/#/R-DME-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Drosophila melanogaster 456216 R-DME-201443 https://reactome.org/PathwayBrowser/#/R-DME-201443 Type II receptor phosphorylates type I receptor IEA Drosophila melanogaster 456216 R-DME-201476 https://reactome.org/PathwayBrowser/#/R-DME-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Drosophila melanogaster 456216 R-DME-201510 https://reactome.org/PathwayBrowser/#/R-DME-201510 PI3K synthesizes PIP3 downstream of ALK IEA Drosophila melanogaster 456216 R-DME-201677 https://reactome.org/PathwayBrowser/#/R-DME-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Drosophila melanogaster 456216 R-DME-201717 https://reactome.org/PathwayBrowser/#/R-DME-201717 CSNK2-mediated phosphorylation of DVL IEA Drosophila melanogaster 456216 R-DME-202111 https://reactome.org/PathwayBrowser/#/R-DME-202111 AKT1 phosphorylates eNOS IEA Drosophila melanogaster 456216 R-DME-202222 https://reactome.org/PathwayBrowser/#/R-DME-202222 Phosphorylation of PKC theta IEA Drosophila melanogaster 456216 R-DME-202248 https://reactome.org/PathwayBrowser/#/R-DME-202248 Phosphorylation of PLC-gamma1 IEA Drosophila melanogaster 456216 R-DME-202541 https://reactome.org/PathwayBrowser/#/R-DME-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Drosophila melanogaster 456216 R-DME-2028284 https://reactome.org/PathwayBrowser/#/R-DME-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Drosophila melanogaster 456216 R-DME-2028555 https://reactome.org/PathwayBrowser/#/R-DME-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Drosophila melanogaster 456216 R-DME-2028589 https://reactome.org/PathwayBrowser/#/R-DME-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Drosophila melanogaster 456216 R-DME-2028591 https://reactome.org/PathwayBrowser/#/R-DME-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Drosophila melanogaster 456216 R-DME-2028629 https://reactome.org/PathwayBrowser/#/R-DME-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Drosophila melanogaster 456216 R-DME-2028635 https://reactome.org/PathwayBrowser/#/R-DME-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Drosophila melanogaster 456216 R-DME-2028670 https://reactome.org/PathwayBrowser/#/R-DME-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Drosophila melanogaster 456216 R-DME-2028673 https://reactome.org/PathwayBrowser/#/R-DME-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Drosophila melanogaster 456216 R-DME-2028675 https://reactome.org/PathwayBrowser/#/R-DME-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Drosophila melanogaster 456216 R-DME-2028679 https://reactome.org/PathwayBrowser/#/R-DME-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Drosophila melanogaster 456216 R-DME-2029454 https://reactome.org/PathwayBrowser/#/R-DME-2029454 Autophosphorylation of PAK1 IEA Drosophila melanogaster 456216 R-DME-2029460 https://reactome.org/PathwayBrowser/#/R-DME-2029460 PAK1 phosphorylates LIMK1 IEA Drosophila melanogaster 456216 R-DME-2029469 https://reactome.org/PathwayBrowser/#/R-DME-2029469 p-ERK phosphorylates WAVEs and ABI IEA Drosophila melanogaster 456216 R-DME-2029473 https://reactome.org/PathwayBrowser/#/R-DME-2029473 Branching and elongation of mother and daughter filaments IEA Drosophila melanogaster 456216 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 456216 R-DME-2046087 https://reactome.org/PathwayBrowser/#/R-DME-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Drosophila melanogaster 456216 R-DME-2046093 https://reactome.org/PathwayBrowser/#/R-DME-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Drosophila melanogaster 456216 R-DME-205136 https://reactome.org/PathwayBrowser/#/R-DME-205136 GTP-bound RAC contributes to JNK activation IEA Drosophila melanogaster 456216 R-DME-209049 https://reactome.org/PathwayBrowser/#/R-DME-209049 Phosphorylation of AXN and APC by SGG IEA Drosophila melanogaster 456216 R-DME-209057 https://reactome.org/PathwayBrowser/#/R-DME-209057 Activated PLL kinase is autophosphorylated in TL:MYD88:TUB:PLL 'signalling complex' TAS Drosophila melanogaster 456216 R-DME-209082 https://reactome.org/PathwayBrowser/#/R-DME-209082 Further phosphorylation of APC by SGG IEA Drosophila melanogaster 456216 R-DME-209087 https://reactome.org/PathwayBrowser/#/R-DME-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Drosophila melanogaster 456216 R-DME-209107 https://reactome.org/PathwayBrowser/#/R-DME-209107 Further phosphorylation of APC by DCO IEA Drosophila melanogaster 456216 R-DME-209109 https://reactome.org/PathwayBrowser/#/R-DME-209109 Further phosphorylation of ARM by SGG TAS Drosophila melanogaster 456216 R-DME-209118 https://reactome.org/PathwayBrowser/#/R-DME-209118 Membrane localised SGG phosphorylates ARR TAS Drosophila melanogaster 456216 R-DME-209134 https://reactome.org/PathwayBrowser/#/R-DME-209134 Phosphorylation of ARM by CKIalpha TAS Drosophila melanogaster 456216 R-DME-209135 https://reactome.org/PathwayBrowser/#/R-DME-209135 GISH further phosphorylates ARR in the receptor complex IEA Drosophila melanogaster 456216 R-DME-209143 https://reactome.org/PathwayBrowser/#/R-DME-209143 Phosphorylation of AXN and APC by DCO IEA Drosophila melanogaster 456216 R-DME-209160 https://reactome.org/PathwayBrowser/#/R-DME-209160 Phosphorylated HOP phosphorylates DOME TAS Drosophila melanogaster 456216 R-DME-209168 https://reactome.org/PathwayBrowser/#/R-DME-209168 Phosphorylation of SMO by CKIalpha TAS Drosophila melanogaster 456216 R-DME-209172 https://reactome.org/PathwayBrowser/#/R-DME-209172 Phosphorylation of CI by SGG TAS Drosophila melanogaster 456216 R-DME-209187 https://reactome.org/PathwayBrowser/#/R-DME-209187 Further phosphorylation of CI by CKIalphaepsilon TAS Drosophila melanogaster 456216 R-DME-209196 https://reactome.org/PathwayBrowser/#/R-DME-209196 Phosphorylation of CI by PKA-C1 TAS Drosophila melanogaster 456216 R-DME-209199 https://reactome.org/PathwayBrowser/#/R-DME-209199 CKA is phosphorylated by phosphorylated BSK kinase TAS Drosophila melanogaster 456216 R-DME-209200 https://reactome.org/PathwayBrowser/#/R-DME-209200 HEP is phosphorylated and activated by Phospho TAK1:TAB2 kinase complex IEA Drosophila melanogaster 456216 R-DME-209210 https://reactome.org/PathwayBrowser/#/R-DME-209210 STAT92E is phosphorylated by phosphorylated HOP TAS Drosophila melanogaster 456216 R-DME-209220 https://reactome.org/PathwayBrowser/#/R-DME-209220 Liberation of CI from SU(FU) repression TAS Drosophila melanogaster 456216 R-DME-209227 https://reactome.org/PathwayBrowser/#/R-DME-209227 Activated Phospho IRD5:KEY dimer phosphorylates REL in the PGN:PGRP-LC oligomer receptor 'signalling complex' TAS Drosophila melanogaster 456216 R-DME-209240 https://reactome.org/PathwayBrowser/#/R-DME-209240 Activated phosphorylated TAK1 kinase phosphorylates and activates IRD5 TAS Drosophila melanogaster 456216 R-DME-209253 https://reactome.org/PathwayBrowser/#/R-DME-209253 Autophosphorylated FU phosphorylates COS TAS Drosophila melanogaster 456216 R-DME-209293 https://reactome.org/PathwayBrowser/#/R-DME-209293 Phosphorylation of CI by CKIalphaepsilon (CKIalpha/DCO) TAS Drosophila melanogaster 456216 R-DME-209298 https://reactome.org/PathwayBrowser/#/R-DME-209298 BSK is phosphorylated and activated by phosphorylated HEP kinase TAS Drosophila melanogaster 456216 R-DME-209320 https://reactome.org/PathwayBrowser/#/R-DME-209320 Activated TAK1 kinase is autophosphorylated TAS Drosophila melanogaster 456216 R-DME-209336 https://reactome.org/PathwayBrowser/#/R-DME-209336 Activated HOP is autophosphorylated and/or transphosphorylated TAS Drosophila melanogaster 456216 R-DME-209341 https://reactome.org/PathwayBrowser/#/R-DME-209341 Phosphorylation of SMO by PKA-C1 TAS Drosophila melanogaster 456216 R-DME-209381 https://reactome.org/PathwayBrowser/#/R-DME-209381 AP-1 transcription factor, JRA:KAY, is phosphorylated by phosphorylated BSK kinase TAS Drosophila melanogaster 456216 R-DME-211164 https://reactome.org/PathwayBrowser/#/R-DME-211164 AKT phosphorylates FOXO1A IEA Drosophila melanogaster 456216 R-DME-212710 https://reactome.org/PathwayBrowser/#/R-DME-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Drosophila melanogaster 456216 R-DME-2130194 https://reactome.org/PathwayBrowser/#/R-DME-2130194 ABL phosphorylates WAVEs IEA Drosophila melanogaster 456216 R-DME-214398 https://reactome.org/PathwayBrowser/#/R-DME-214398 Activated Phospho IRD5:KEY dimer phosphorylates REL in the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' TAS Drosophila melanogaster 456216 R-DME-214845 https://reactome.org/PathwayBrowser/#/R-DME-214845 CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' TAS Drosophila melanogaster 456216 R-DME-214859 https://reactome.org/PathwayBrowser/#/R-DME-214859 Activated PLL kinase is autophosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' TAS Drosophila melanogaster 456216 R-DME-214860 https://reactome.org/PathwayBrowser/#/R-DME-214860 CACT and DL/DIF dimer are phosphorylated in TL:MYD88:TUB:PLL 'signalling complex' TAS Drosophila melanogaster 456216 R-DME-2168079 https://reactome.org/PathwayBrowser/#/R-DME-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Drosophila melanogaster 456216 R-DME-2176475 https://reactome.org/PathwayBrowser/#/R-DME-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Drosophila melanogaster 456216 R-DME-2197690 https://reactome.org/PathwayBrowser/#/R-DME-2197690 Detachment of WASP/WAVE IEA Drosophila melanogaster 456216 R-DME-2214351 https://reactome.org/PathwayBrowser/#/R-DME-2214351 PLK1 phosphorylates GORASP1 IEA Drosophila melanogaster 456216 R-DME-2316434 https://reactome.org/PathwayBrowser/#/R-DME-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-2422927 https://reactome.org/PathwayBrowser/#/R-DME-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Drosophila melanogaster 456216 R-DME-2424487 https://reactome.org/PathwayBrowser/#/R-DME-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Drosophila melanogaster 456216 R-DME-2430535 https://reactome.org/PathwayBrowser/#/R-DME-2430535 MASTL phosphorylates ENSA IEA Drosophila melanogaster 456216 R-DME-2466068 https://reactome.org/PathwayBrowser/#/R-DME-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Drosophila melanogaster 456216 R-DME-2468293 https://reactome.org/PathwayBrowser/#/R-DME-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Drosophila melanogaster 456216 R-DME-2529020 https://reactome.org/PathwayBrowser/#/R-DME-2529020 CK2 phosphorylates condensin I subunits IEA Drosophila melanogaster 456216 R-DME-2562526 https://reactome.org/PathwayBrowser/#/R-DME-2562526 PLK1 phosphorylates OPTN IEA Drosophila melanogaster 456216 R-DME-265682 https://reactome.org/PathwayBrowser/#/R-DME-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Drosophila melanogaster 456216 R-DME-265783 https://reactome.org/PathwayBrowser/#/R-DME-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Drosophila melanogaster 456216 R-DME-266082 https://reactome.org/PathwayBrowser/#/R-DME-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Drosophila melanogaster 456216 R-DME-2730835 https://reactome.org/PathwayBrowser/#/R-DME-2730835 Autophosphorylation of PKC-theta IEA Drosophila melanogaster 456216 R-DME-2730841 https://reactome.org/PathwayBrowser/#/R-DME-2730841 Phosphorylation and activation of VAV IEA Drosophila melanogaster 456216 R-DME-2730856 https://reactome.org/PathwayBrowser/#/R-DME-2730856 Autophosphorylation of PAK IEA Drosophila melanogaster 456216 R-DME-2730858 https://reactome.org/PathwayBrowser/#/R-DME-2730858 Autophosphorylation of BTK/ITK IEA Drosophila melanogaster 456216 R-DME-2730862 https://reactome.org/PathwayBrowser/#/R-DME-2730862 Autophosphorylation of LYN kinase IEA Drosophila melanogaster 456216 R-DME-2730870 https://reactome.org/PathwayBrowser/#/R-DME-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Drosophila melanogaster 456216 R-DME-2990882 https://reactome.org/PathwayBrowser/#/R-DME-2990882 CDK1 phosphorylates NUP98 IEA Drosophila melanogaster 456216 R-DME-3000327 https://reactome.org/PathwayBrowser/#/R-DME-3000327 PLK1 phosphorylates BORA IEA Drosophila melanogaster 456216 R-DME-3095901 https://reactome.org/PathwayBrowser/#/R-DME-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Drosophila melanogaster 456216 R-DME-3132737 https://reactome.org/PathwayBrowser/#/R-DME-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Drosophila melanogaster 456216 R-DME-3228469 https://reactome.org/PathwayBrowser/#/R-DME-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Drosophila melanogaster 456216 R-DME-3229102 https://reactome.org/PathwayBrowser/#/R-DME-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Drosophila melanogaster 456216 R-DME-3249371 https://reactome.org/PathwayBrowser/#/R-DME-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Drosophila melanogaster 456216 R-DME-3249379 https://reactome.org/PathwayBrowser/#/R-DME-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Drosophila melanogaster 456216 R-DME-3249390 https://reactome.org/PathwayBrowser/#/R-DME-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Drosophila melanogaster 456216 R-DME-3371422 https://reactome.org/PathwayBrowser/#/R-DME-3371422 ATP hydrolysis by HSP70 IEA Drosophila melanogaster 456216 R-DME-3371435 https://reactome.org/PathwayBrowser/#/R-DME-3371435 Constitutive phosphorylation by GSK3 IEA Drosophila melanogaster 456216 R-DME-3371503 https://reactome.org/PathwayBrowser/#/R-DME-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Drosophila melanogaster 456216 R-DME-3371531 https://reactome.org/PathwayBrowser/#/R-DME-3371531 Constitutive phosphorylation by pERK1/2 IEA Drosophila melanogaster 456216 R-DME-350362 https://reactome.org/PathwayBrowser/#/R-DME-350362 ROK phosphorylates MBS TAS Drosophila melanogaster 456216 R-DME-350444 https://reactome.org/PathwayBrowser/#/R-DME-350444 ROK phosphorylates SQH TAS Drosophila melanogaster 456216 R-DME-373747 https://reactome.org/PathwayBrowser/#/R-DME-373747 Phosphorylation of nephrin by FYN IEA Drosophila melanogaster 456216 R-DME-373750 https://reactome.org/PathwayBrowser/#/R-DME-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Drosophila melanogaster 456216 R-DME-374664 https://reactome.org/PathwayBrowser/#/R-DME-374664 Phosphorylation and activation of Ezrin IEA Drosophila melanogaster 456216 R-DME-374701 https://reactome.org/PathwayBrowser/#/R-DME-374701 Phosphorylation of DCC by Fyn IEA Drosophila melanogaster 456216 R-DME-3769394 https://reactome.org/PathwayBrowser/#/R-DME-3769394 AKT phosphorylates CBY1 IEA Drosophila melanogaster 456216 R-DME-377186 https://reactome.org/PathwayBrowser/#/R-DME-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Drosophila melanogaster 456216 R-DME-3772435 https://reactome.org/PathwayBrowser/#/R-DME-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Drosophila melanogaster 456216 R-DME-3772436 https://reactome.org/PathwayBrowser/#/R-DME-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Drosophila melanogaster 456216 R-DME-377640 https://reactome.org/PathwayBrowser/#/R-DME-377640 Autophosphorylation of SRC IEA Drosophila melanogaster 456216 R-DME-3788705 https://reactome.org/PathwayBrowser/#/R-DME-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Drosophila melanogaster 456216 R-DME-380278 https://reactome.org/PathwayBrowser/#/R-DME-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Drosophila melanogaster 456216 R-DME-380780 https://reactome.org/PathwayBrowser/#/R-DME-380780 Activation of Src IEA Drosophila melanogaster 456216 R-DME-380927 https://reactome.org/PathwayBrowser/#/R-DME-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Drosophila melanogaster 456216 R-DME-381091 https://reactome.org/PathwayBrowser/#/R-DME-381091 IRE1 dimer autophosphorylates IEA Drosophila melanogaster 456216 R-DME-381111 https://reactome.org/PathwayBrowser/#/R-DME-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Drosophila melanogaster 456216 R-DME-382560 https://reactome.org/PathwayBrowser/#/R-DME-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Drosophila melanogaster 456216 R-DME-382575 https://reactome.org/PathwayBrowser/#/R-DME-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Drosophila melanogaster 456216 R-DME-383190 https://reactome.org/PathwayBrowser/#/R-DME-383190 HCO3- transport through ion channel IEA Drosophila melanogaster 456216 R-DME-3857329 https://reactome.org/PathwayBrowser/#/R-DME-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Drosophila melanogaster 456216 R-DME-389083 https://reactome.org/PathwayBrowser/#/R-DME-389083 Autophosphorylation of PDGF alpha receptors IEA Drosophila melanogaster 456216 R-DME-389086 https://reactome.org/PathwayBrowser/#/R-DME-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Drosophila melanogaster 456216 R-DME-390025 https://reactome.org/PathwayBrowser/#/R-DME-390025 Phosphorylated WTS autophosphorylates TAS Drosophila melanogaster 456216 R-DME-390035 https://reactome.org/PathwayBrowser/#/R-DME-390035 HPO dimer autophosphorylates TAS Drosophila melanogaster 456216 R-DME-390044 https://reactome.org/PathwayBrowser/#/R-DME-390044 YKI is phosphorylated by and then dissociates from phosphorylated WTS TAS Drosophila melanogaster 456216 R-DME-390112 https://reactome.org/PathwayBrowser/#/R-DME-390112 Phosphorylated HPO dimer phosphorylates WTS TAS Drosophila melanogaster 456216 R-DME-390120 https://reactome.org/PathwayBrowser/#/R-DME-390120 Phosphorylated HPO dimer phosphorylates TH TAS Drosophila melanogaster 456216 R-DME-390145 https://reactome.org/PathwayBrowser/#/R-DME-390145 Phosphorylated HPO dimer phosphorylates SAV TAS Drosophila melanogaster 456216 R-DME-390154 https://reactome.org/PathwayBrowser/#/R-DME-390154 MATS is phosphorylated by HPO dimer and binds to phosphorylated WTS TAS Drosophila melanogaster 456216 R-DME-391266 https://reactome.org/PathwayBrowser/#/R-DME-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Drosophila melanogaster 456216 R-DME-392195 https://reactome.org/PathwayBrowser/#/R-DME-392195 Gi activation by P2Y purinoceptor 12 IEA Drosophila melanogaster 456216 R-DME-392300 https://reactome.org/PathwayBrowser/#/R-DME-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-3928578 https://reactome.org/PathwayBrowser/#/R-DME-3928578 EPH receptors autophosphorylate IEA Drosophila melanogaster 456216 R-DME-3928604 https://reactome.org/PathwayBrowser/#/R-DME-3928604 SFKs phosphorylate VAV2,3 IEA Drosophila melanogaster 456216 R-DME-3928620 https://reactome.org/PathwayBrowser/#/R-DME-3928620 PAK1 autophosphorylates IEA Drosophila melanogaster 456216 R-DME-3928625 https://reactome.org/PathwayBrowser/#/R-DME-3928625 PAKs autophosphorylate IEA Drosophila melanogaster 456216 R-DME-3928627 https://reactome.org/PathwayBrowser/#/R-DME-3928627 EPHB phosphorylates TIAM1 IEA Drosophila melanogaster 456216 R-DME-3928640 https://reactome.org/PathwayBrowser/#/R-DME-3928640 PAKs phosphorylate MLC IEA Drosophila melanogaster 456216 R-DME-399939 https://reactome.org/PathwayBrowser/#/R-DME-399939 Autophosphorylation of PAK IEA Drosophila melanogaster 456216 R-DME-399944 https://reactome.org/PathwayBrowser/#/R-DME-399944 Phosphorylation of CRMPs by Cdk5 IEA Drosophila melanogaster 456216 R-DME-399947 https://reactome.org/PathwayBrowser/#/R-DME-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Drosophila melanogaster 456216 R-DME-399951 https://reactome.org/PathwayBrowser/#/R-DME-399951 Phosphorylation of CRMPs by GSK3beta IEA Drosophila melanogaster 456216 R-DME-399952 https://reactome.org/PathwayBrowser/#/R-DME-399952 Phosphorylation of LIMK-1 by PAK IEA Drosophila melanogaster 456216 R-DME-4086410 https://reactome.org/PathwayBrowser/#/R-DME-4086410 CDK1 phosphorylates BORA IEA Drosophila melanogaster 456216 R-DME-4093332 https://reactome.org/PathwayBrowser/#/R-DME-4093332 p-EPHB phosphorylates SDC2 IEA Drosophila melanogaster 456216 R-DME-416639 https://reactome.org/PathwayBrowser/#/R-DME-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Drosophila melanogaster 456216 R-DME-416985 https://reactome.org/PathwayBrowser/#/R-DME-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Drosophila melanogaster 456216 R-DME-419644 https://reactome.org/PathwayBrowser/#/R-DME-419644 Transphosphorylation of pLIMK1 IEA Drosophila melanogaster 456216 R-DME-421007 https://reactome.org/PathwayBrowser/#/R-DME-421007 Endocytosis of Ca impermeable AMPA receptors IEA Drosophila melanogaster 456216 R-DME-426240 https://reactome.org/PathwayBrowser/#/R-DME-426240 DAG kinase produces phosphatidic acid from DAG IEA Drosophila melanogaster 456216 R-DME-428273 https://reactome.org/PathwayBrowser/#/R-DME-428273 SPHK1 phosphorylates sphingoid IEA Drosophila melanogaster 456216 R-DME-428888 https://reactome.org/PathwayBrowser/#/R-DME-428888 Phosphorylation of ROBO1 by ABL kinase IEA Drosophila melanogaster 456216 R-DME-428941 https://reactome.org/PathwayBrowser/#/R-DME-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Drosophila melanogaster 456216 R-DME-429157 https://reactome.org/PathwayBrowser/#/R-DME-429157 ABCC4 accumulation of dense granule contents IEA Drosophila melanogaster 456216 R-DME-429441 https://reactome.org/PathwayBrowser/#/R-DME-429441 SYK activation by SRC IEA Drosophila melanogaster 456216 R-DME-429449 https://reactome.org/PathwayBrowser/#/R-DME-429449 Syk activation leads to SLP-76 activation IEA Drosophila melanogaster 456216 R-DME-429698 https://reactome.org/PathwayBrowser/#/R-DME-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Drosophila melanogaster 456216 R-DME-429714 https://reactome.org/PathwayBrowser/#/R-DME-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Drosophila melanogaster 456216 R-DME-432148 https://reactome.org/PathwayBrowser/#/R-DME-432148 Fgr may phosphorylate p38 MAPK IEA Drosophila melanogaster 456216 R-DME-432232 https://reactome.org/PathwayBrowser/#/R-DME-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Drosophila melanogaster 456216 R-DME-432513 https://reactome.org/PathwayBrowser/#/R-DME-432513 CLK is phosphorylated by DCO TAS Drosophila melanogaster 456216 R-DME-432535 https://reactome.org/PathwayBrowser/#/R-DME-432535 TIM is phosphorylated by CK2 TAS Drosophila melanogaster 456216 R-DME-432559 https://reactome.org/PathwayBrowser/#/R-DME-432559 PER is phosphorylated by DCO TAS Drosophila melanogaster 456216 R-DME-432590 https://reactome.org/PathwayBrowser/#/R-DME-432590 Phosphorylated PER is phosphorylated by CK2 TAS Drosophila melanogaster 456216 R-DME-4332358 https://reactome.org/PathwayBrowser/#/R-DME-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Drosophila melanogaster 456216 R-DME-4332363 https://reactome.org/PathwayBrowser/#/R-DME-4332363 Autophosphorylation and activation of CAMK2 IEA Drosophila melanogaster 456216 R-DME-437162 https://reactome.org/PathwayBrowser/#/R-DME-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-4411383 https://reactome.org/PathwayBrowser/#/R-DME-4411383 NLK phosphorylates TCF/LEF IEA Drosophila melanogaster 456216 R-DME-4411402 https://reactome.org/PathwayBrowser/#/R-DME-4411402 Activation of NLK IEA Drosophila melanogaster 456216 R-DME-442724 https://reactome.org/PathwayBrowser/#/R-DME-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Drosophila melanogaster 456216 R-DME-445072 https://reactome.org/PathwayBrowser/#/R-DME-445072 Interaction of PAK1 with Rac1-GTP IEA Drosophila melanogaster 456216 R-DME-445079 https://reactome.org/PathwayBrowser/#/R-DME-445079 Phosphorylation of L1 by ERK IEA Drosophila melanogaster 456216 R-DME-445699 https://reactome.org/PathwayBrowser/#/R-DME-445699 ATP Hydrolysis By Myosin IEA Drosophila melanogaster 456216 R-DME-445705 https://reactome.org/PathwayBrowser/#/R-DME-445705 Release Of ADP From Myosin IEA Drosophila melanogaster 456216 R-DME-447074 https://reactome.org/PathwayBrowser/#/R-DME-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Drosophila melanogaster 456216 R-DME-448955 https://reactome.org/PathwayBrowser/#/R-DME-448955 Phosphorylation of MEF2 proteins by p38 IEA Drosophila melanogaster 456216 R-DME-450222 https://reactome.org/PathwayBrowser/#/R-DME-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Drosophila melanogaster 456216 R-DME-450325 https://reactome.org/PathwayBrowser/#/R-DME-450325 c-FOS activation by phospho ERK1/2 IEA Drosophila melanogaster 456216 R-DME-450333 https://reactome.org/PathwayBrowser/#/R-DME-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Drosophila melanogaster 456216 R-DME-450337 https://reactome.org/PathwayBrowser/#/R-DME-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Drosophila melanogaster 456216 R-DME-450346 https://reactome.org/PathwayBrowser/#/R-DME-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Drosophila melanogaster 456216 R-DME-450463 https://reactome.org/PathwayBrowser/#/R-DME-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Drosophila melanogaster 456216 R-DME-450474 https://reactome.org/PathwayBrowser/#/R-DME-450474 MK2 phosphorylates BRF1 IEA Drosophila melanogaster 456216 R-DME-450490 https://reactome.org/PathwayBrowser/#/R-DME-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Drosophila melanogaster 456216 R-DME-450499 https://reactome.org/PathwayBrowser/#/R-DME-450499 Protein Kinase B (AKT) phosphorylates KSRP IEA Drosophila melanogaster 456216 R-DME-450533 https://reactome.org/PathwayBrowser/#/R-DME-450533 PKCdelta phosphorylates HuR IEA Drosophila melanogaster 456216 R-DME-450550 https://reactome.org/PathwayBrowser/#/R-DME-450550 PKCalpha phosphorylates HuR IEA Drosophila melanogaster 456216 R-DME-450723 https://reactome.org/PathwayBrowser/#/R-DME-450723 RAC1:GTP and MSN activate HEP TAS Drosophila melanogaster 456216 R-DME-450827 https://reactome.org/PathwayBrowser/#/R-DME-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Drosophila melanogaster 456216 R-DME-451856 https://reactome.org/PathwayBrowser/#/R-DME-451856 FT is phosphorylated by DCO TAS Drosophila melanogaster 456216 R-DME-4793911 https://reactome.org/PathwayBrowser/#/R-DME-4793911 MAPKAPK2 phosphorylates HSF1 IEA Drosophila melanogaster 456216 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 456216 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 456216 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 456216 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 456216 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 456216 R-DME-504054 https://reactome.org/PathwayBrowser/#/R-DME-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Drosophila melanogaster 456216 R-DME-508040 https://reactome.org/PathwayBrowser/#/R-DME-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Drosophila melanogaster 456216 R-DME-5082387 https://reactome.org/PathwayBrowser/#/R-DME-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Drosophila melanogaster 456216 R-DME-5082405 https://reactome.org/PathwayBrowser/#/R-DME-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Drosophila melanogaster 456216 R-DME-508308 https://reactome.org/PathwayBrowser/#/R-DME-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Drosophila melanogaster 456216 R-DME-5195402 https://reactome.org/PathwayBrowser/#/R-DME-5195402 CDK1 phosphorylates LPIN IEA Drosophila melanogaster 456216 R-DME-5218804 https://reactome.org/PathwayBrowser/#/R-DME-5218804 p38 MAPK activation by VEGFR IEA Drosophila melanogaster 456216 R-DME-5218805 https://reactome.org/PathwayBrowser/#/R-DME-5218805 PKC autophosphorylates IEA Drosophila melanogaster 456216 R-DME-5218806 https://reactome.org/PathwayBrowser/#/R-DME-5218806 FYN autophosphorylates IEA Drosophila melanogaster 456216 R-DME-5218812 https://reactome.org/PathwayBrowser/#/R-DME-5218812 FYN phosphorylates PAK2 IEA Drosophila melanogaster 456216 R-DME-5218814 https://reactome.org/PathwayBrowser/#/R-DME-5218814 PAK2 autophorylates IEA Drosophila melanogaster 456216 R-DME-5218819 https://reactome.org/PathwayBrowser/#/R-DME-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-5218821 https://reactome.org/PathwayBrowser/#/R-DME-5218821 PDK1 phosphorylates PKC IEA Drosophila melanogaster 456216 R-DME-5218823 https://reactome.org/PathwayBrowser/#/R-DME-5218823 PKC phosphorylates sphingosine kinase 1 IEA Drosophila melanogaster 456216 R-DME-5218845 https://reactome.org/PathwayBrowser/#/R-DME-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Drosophila melanogaster 456216 R-DME-5218854 https://reactome.org/PathwayBrowser/#/R-DME-5218854 p-Y420-FYN is phosphorylated on S21 IEA Drosophila melanogaster 456216 R-DME-5218916 https://reactome.org/PathwayBrowser/#/R-DME-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Drosophila melanogaster 456216 R-DME-5229343 https://reactome.org/PathwayBrowser/#/R-DME-5229343 AXIN is phosphorylated in the destruction complex IEA Drosophila melanogaster 456216 R-DME-5244669 https://reactome.org/PathwayBrowser/#/R-DME-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Drosophila melanogaster 456216 R-DME-5251989 https://reactome.org/PathwayBrowser/#/R-DME-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Drosophila melanogaster 456216 R-DME-5357472 https://reactome.org/PathwayBrowser/#/R-DME-5357472 PAK1-3 autophosphorylates IEA Drosophila melanogaster 456216 R-DME-5357477 https://reactome.org/PathwayBrowser/#/R-DME-5357477 PAK1-3 phosphorylates VE-cadherin IEA Drosophila melanogaster 456216 R-DME-5357831 https://reactome.org/PathwayBrowser/#/R-DME-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Drosophila melanogaster 456216 R-DME-5358525 https://reactome.org/PathwayBrowser/#/R-DME-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Drosophila melanogaster 456216 R-DME-5358912 https://reactome.org/PathwayBrowser/#/R-DME-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Drosophila melanogaster 456216 R-DME-5362459 https://reactome.org/PathwayBrowser/#/R-DME-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Drosophila melanogaster 456216 R-DME-5444516 https://reactome.org/PathwayBrowser/#/R-DME-5444516 Formation of MSH2:MSH6 Complex IEA Drosophila melanogaster 456216 R-DME-5607726 https://reactome.org/PathwayBrowser/#/R-DME-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Drosophila melanogaster 456216 R-DME-5610720 https://reactome.org/PathwayBrowser/#/R-DME-5610720 PKA phosphorylates GLI3 IEA Drosophila melanogaster 456216 R-DME-5610722 https://reactome.org/PathwayBrowser/#/R-DME-5610722 CK1 phosphorylates p-GLI3 IEA Drosophila melanogaster 456216 R-DME-5610732 https://reactome.org/PathwayBrowser/#/R-DME-5610732 GSK3 phosphorylates p-GLI3 IEA Drosophila melanogaster 456216 R-DME-5617179 https://reactome.org/PathwayBrowser/#/R-DME-5617179 PRKACA phosphorylates TNNI3 IEA Drosophila melanogaster 456216 R-DME-5618085 https://reactome.org/PathwayBrowser/#/R-DME-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Drosophila melanogaster 456216 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 456216 R-DME-5618098 https://reactome.org/PathwayBrowser/#/R-DME-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Drosophila melanogaster 456216 R-DME-5618105 https://reactome.org/PathwayBrowser/#/R-DME-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Drosophila melanogaster 456216 R-DME-5618107 https://reactome.org/PathwayBrowser/#/R-DME-5618107 ATP binding to HSP90 triggers conformation change IEA Drosophila melanogaster 456216 R-DME-5618110 https://reactome.org/PathwayBrowser/#/R-DME-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Drosophila melanogaster 456216 R-DME-5621363 https://reactome.org/PathwayBrowser/#/R-DME-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Drosophila melanogaster 456216 R-DME-5623667 https://reactome.org/PathwayBrowser/#/R-DME-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Drosophila melanogaster 456216 R-DME-5624473 https://reactome.org/PathwayBrowser/#/R-DME-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Drosophila melanogaster 456216 R-DME-5624486 https://reactome.org/PathwayBrowser/#/R-DME-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Drosophila melanogaster 456216 R-DME-5624492 https://reactome.org/PathwayBrowser/#/R-DME-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Drosophila melanogaster 456216 R-DME-5625784 https://reactome.org/PathwayBrowser/#/R-DME-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Drosophila melanogaster 456216 R-DME-5627775 https://reactome.org/PathwayBrowser/#/R-DME-5627775 Autophosphorylation of PAK1,2,3 IEA Drosophila melanogaster 456216 R-DME-5635842 https://reactome.org/PathwayBrowser/#/R-DME-5635842 ULK3 phosphorylates GLI IEA Drosophila melanogaster 456216 R-DME-5654147 https://reactome.org/PathwayBrowser/#/R-DME-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Drosophila melanogaster 456216 R-DME-5654149 https://reactome.org/PathwayBrowser/#/R-DME-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Drosophila melanogaster 456216 R-DME-5654151 https://reactome.org/PathwayBrowser/#/R-DME-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Drosophila melanogaster 456216 R-DME-5654222 https://reactome.org/PathwayBrowser/#/R-DME-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Drosophila melanogaster 456216 R-DME-5654397 https://reactome.org/PathwayBrowser/#/R-DME-5654397 Activated FGFR2 phosphorylates FRS2 IEA Drosophila melanogaster 456216 R-DME-5654407 https://reactome.org/PathwayBrowser/#/R-DME-5654407 Activated FGFR2 phosphorylates SHC1 IEA Drosophila melanogaster 456216 R-DME-5654408 https://reactome.org/PathwayBrowser/#/R-DME-5654408 Activated FGFR3 phosphorylates FRS2 IEA Drosophila melanogaster 456216 R-DME-5654418 https://reactome.org/PathwayBrowser/#/R-DME-5654418 Activated FGFR4 phosphorylates FRS2 IEA Drosophila melanogaster 456216 R-DME-5654428 https://reactome.org/PathwayBrowser/#/R-DME-5654428 Activated FGFR4 phosphorylates SHC1 IEA Drosophila melanogaster 456216 R-DME-5654560 https://reactome.org/PathwayBrowser/#/R-DME-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Drosophila melanogaster 456216 R-DME-5654562 https://reactome.org/PathwayBrowser/#/R-DME-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Drosophila melanogaster 456216 R-DME-5654565 https://reactome.org/PathwayBrowser/#/R-DME-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Drosophila melanogaster 456216 R-DME-5654566 https://reactome.org/PathwayBrowser/#/R-DME-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Drosophila melanogaster 456216 R-DME-5654575 https://reactome.org/PathwayBrowser/#/R-DME-5654575 Activated FGFR1 phosphorylates FRS2 IEA Drosophila melanogaster 456216 R-DME-5654578 https://reactome.org/PathwayBrowser/#/R-DME-5654578 Activated FGFR1 phosphorylates FRS3 IEA Drosophila melanogaster 456216 R-DME-5654582 https://reactome.org/PathwayBrowser/#/R-DME-5654582 Activated FGFR1 phosphorylates SHC1 IEA Drosophila melanogaster 456216 R-DME-5654587 https://reactome.org/PathwayBrowser/#/R-DME-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Drosophila melanogaster 456216 R-DME-5654605 https://reactome.org/PathwayBrowser/#/R-DME-5654605 Activated FGFR2 phosphorylates FRS3 IEA Drosophila melanogaster 456216 R-DME-5654607 https://reactome.org/PathwayBrowser/#/R-DME-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Drosophila melanogaster 456216 R-DME-5654628 https://reactome.org/PathwayBrowser/#/R-DME-5654628 Activated FGFR3 phosphorylates FRS3 IEA Drosophila melanogaster 456216 R-DME-5654631 https://reactome.org/PathwayBrowser/#/R-DME-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Drosophila melanogaster 456216 R-DME-5654634 https://reactome.org/PathwayBrowser/#/R-DME-5654634 Activated FGFR3 phosphorylates SHC1 IEA Drosophila melanogaster 456216 R-DME-5654653 https://reactome.org/PathwayBrowser/#/R-DME-5654653 Activated FGFR4 phosphorylates FRS3 IEA Drosophila melanogaster 456216 R-DME-5654655 https://reactome.org/PathwayBrowser/#/R-DME-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Drosophila melanogaster 456216 R-DME-5654690 https://reactome.org/PathwayBrowser/#/R-DME-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-5654692 https://reactome.org/PathwayBrowser/#/R-DME-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-5654697 https://reactome.org/PathwayBrowser/#/R-DME-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-5654701 https://reactome.org/PathwayBrowser/#/R-DME-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-5654705 https://reactome.org/PathwayBrowser/#/R-DME-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-5654709 https://reactome.org/PathwayBrowser/#/R-DME-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-5654714 https://reactome.org/PathwayBrowser/#/R-DME-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-5654717 https://reactome.org/PathwayBrowser/#/R-DME-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-5654989 https://reactome.org/PathwayBrowser/#/R-DME-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Drosophila melanogaster 456216 R-DME-5662466 https://reactome.org/PathwayBrowser/#/R-DME-5662466 XYLB phosphorylates D-xylulose IEA Drosophila melanogaster 456216 R-DME-5665868 https://reactome.org/PathwayBrowser/#/R-DME-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Drosophila melanogaster 456216 R-DME-5668932 https://reactome.org/PathwayBrowser/#/R-DME-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Drosophila melanogaster 456216 R-DME-5668947 https://reactome.org/PathwayBrowser/#/R-DME-5668947 PAK1 phosphorylates myosin phosphatase IEA Drosophila melanogaster 456216 R-DME-5669250 https://reactome.org/PathwayBrowser/#/R-DME-5669250 PAK1 phosphorylates FLNA IEA Drosophila melanogaster 456216 R-DME-5671749 https://reactome.org/PathwayBrowser/#/R-DME-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Drosophila melanogaster 456216 R-DME-5671763 https://reactome.org/PathwayBrowser/#/R-DME-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Drosophila melanogaster 456216 R-DME-5672008 https://reactome.org/PathwayBrowser/#/R-DME-5672008 Thr-180 of ULK1 is phosphorylated IEA Drosophila melanogaster 456216 R-DME-5672010 https://reactome.org/PathwayBrowser/#/R-DME-5672010 Active MTORC1 phosphorylates ULK1 IEA Drosophila melanogaster 456216 R-DME-5672012 https://reactome.org/PathwayBrowser/#/R-DME-5672012 Beclin-1 complex phosphorylates PtdIns IEA Drosophila melanogaster 456216 R-DME-5672828 https://reactome.org/PathwayBrowser/#/R-DME-5672828 mTORC1 phosphorylates AKT1S1 IEA Drosophila melanogaster 456216 R-DME-5672948 https://reactome.org/PathwayBrowser/#/R-DME-5672948 MARK3 phosphorylates KSR1 IEA Drosophila melanogaster 456216 R-DME-5672969 https://reactome.org/PathwayBrowser/#/R-DME-5672969 Phosphorylation of RAF IEA Drosophila melanogaster 456216 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 456216 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 456216 R-DME-5673768 https://reactome.org/PathwayBrowser/#/R-DME-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Drosophila melanogaster 456216 R-DME-5674130 https://reactome.org/PathwayBrowser/#/R-DME-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Drosophila melanogaster 456216 R-DME-5674373 https://reactome.org/PathwayBrowser/#/R-DME-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Drosophila melanogaster 456216 R-DME-5674496 https://reactome.org/PathwayBrowser/#/R-DME-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Drosophila melanogaster 456216 R-DME-5675194 https://reactome.org/PathwayBrowser/#/R-DME-5675194 Activated MAPK phosphorylates RAF1 IEA Drosophila melanogaster 456216 R-DME-5675198 https://reactome.org/PathwayBrowser/#/R-DME-5675198 Activated MAPKs phosphorylate BRAF IEA Drosophila melanogaster 456216 R-DME-5675868 https://reactome.org/PathwayBrowser/#/R-DME-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Drosophila melanogaster 456216 R-DME-5678863 https://reactome.org/PathwayBrowser/#/R-DME-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Drosophila melanogaster 456216 R-DME-5679041 https://reactome.org/PathwayBrowser/#/R-DME-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 456216 R-DME-5679205 https://reactome.org/PathwayBrowser/#/R-DME-5679205 ULK1 phosphorylates Beclin-1 IEA Drosophila melanogaster 456216 R-DME-5682026 https://reactome.org/PathwayBrowser/#/R-DME-5682026 MRN bound to shortened telomeres activates ATM IEA Drosophila melanogaster 456216 R-DME-5682101 https://reactome.org/PathwayBrowser/#/R-DME-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Drosophila melanogaster 456216 R-DME-5682285 https://reactome.org/PathwayBrowser/#/R-DME-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Drosophila melanogaster 456216 R-DME-5682598 https://reactome.org/PathwayBrowser/#/R-DME-5682598 ATM phosphorylates HERC2 IEA Drosophila melanogaster 456216 R-DME-5682983 https://reactome.org/PathwayBrowser/#/R-DME-5682983 ATM phosphorylates WHSC1 IEA Drosophila melanogaster 456216 R-DME-5683714 https://reactome.org/PathwayBrowser/#/R-DME-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Drosophila melanogaster 456216 R-DME-5683792 https://reactome.org/PathwayBrowser/#/R-DME-5683792 p-T68-CHEK2 autophosphorylates IEA Drosophila melanogaster 456216 R-DME-5683964 https://reactome.org/PathwayBrowser/#/R-DME-5683964 ATM phosphorylates EYA1-4 IEA Drosophila melanogaster 456216 R-DME-5684096 https://reactome.org/PathwayBrowser/#/R-DME-5684096 CDK2 phosphorylates RBBP8 IEA Drosophila melanogaster 456216 R-DME-5684140 https://reactome.org/PathwayBrowser/#/R-DME-5684140 ATM phosphorylates RBBP8 IEA Drosophila melanogaster 456216 R-DME-5684887 https://reactome.org/PathwayBrowser/#/R-DME-5684887 Activation of CHEK1 at resected DNA DSBs IEA Drosophila melanogaster 456216 R-DME-5685156 https://reactome.org/PathwayBrowser/#/R-DME-5685156 ATR phosphorylates RPA2 IEA Drosophila melanogaster 456216 R-DME-5685230 https://reactome.org/PathwayBrowser/#/R-DME-5685230 CHEK1 phosphorylates RAD51 IEA Drosophila melanogaster 456216 R-DME-5686578 https://reactome.org/PathwayBrowser/#/R-DME-5686578 Activated ATM phosphorylates ABL1 IEA Drosophila melanogaster 456216 R-DME-5690996 https://reactome.org/PathwayBrowser/#/R-DME-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Drosophila melanogaster 456216 R-DME-5692462 https://reactome.org/PathwayBrowser/#/R-DME-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Drosophila melanogaster 456216 R-DME-5693536 https://reactome.org/PathwayBrowser/#/R-DME-5693536 ATM phosphorylates MDC1 IEA Drosophila melanogaster 456216 R-DME-5693540 https://reactome.org/PathwayBrowser/#/R-DME-5693540 MRN activates ATM IEA Drosophila melanogaster 456216 R-DME-5693549 https://reactome.org/PathwayBrowser/#/R-DME-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Drosophila melanogaster 456216 R-DME-5693598 https://reactome.org/PathwayBrowser/#/R-DME-5693598 ATM phosphorylates NBN IEA Drosophila melanogaster 456216 R-DME-5693609 https://reactome.org/PathwayBrowser/#/R-DME-5693609 ATM phosphorylates TP53 at S15 IEA Drosophila melanogaster 456216 R-DME-5696074 https://reactome.org/PathwayBrowser/#/R-DME-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Drosophila melanogaster 456216 R-DME-5696839 https://reactome.org/PathwayBrowser/#/R-DME-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Drosophila melanogaster 456216 R-DME-6782131 https://reactome.org/PathwayBrowser/#/R-DME-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Drosophila melanogaster 456216 R-DME-6788798 https://reactome.org/PathwayBrowser/#/R-DME-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 456216 R-DME-6788810 https://reactome.org/PathwayBrowser/#/R-DME-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 456216 R-DME-6797606 https://reactome.org/PathwayBrowser/#/R-DME-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Drosophila melanogaster 456216 R-DME-6798174 https://reactome.org/PathwayBrowser/#/R-DME-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Drosophila melanogaster 456216 R-DME-6798372 https://reactome.org/PathwayBrowser/#/R-DME-6798372 ATM phosphorylates DYRK2 IEA Drosophila melanogaster 456216 R-DME-6798374 https://reactome.org/PathwayBrowser/#/R-DME-6798374 DYRK2 phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-6799097 https://reactome.org/PathwayBrowser/#/R-DME-6799097 ATM phosphorylates ZNF420 IEA Drosophila melanogaster 456216 R-DME-6799246 https://reactome.org/PathwayBrowser/#/R-DME-6799246 CHEK1 phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-6799332 https://reactome.org/PathwayBrowser/#/R-DME-6799332 ATR phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-6799409 https://reactome.org/PathwayBrowser/#/R-DME-6799409 HIPK2 phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-6799495 https://reactome.org/PathwayBrowser/#/R-DME-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Drosophila melanogaster 456216 R-DME-6800490 https://reactome.org/PathwayBrowser/#/R-DME-6800490 ATM phosphorylates PIDD1 IEA Drosophila melanogaster 456216 R-DME-6801342 https://reactome.org/PathwayBrowser/#/R-DME-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Drosophila melanogaster 456216 R-DME-6801456 https://reactome.org/PathwayBrowser/#/R-DME-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Drosophila melanogaster 456216 R-DME-6803771 https://reactome.org/PathwayBrowser/#/R-DME-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Drosophila melanogaster 456216 R-DME-6805059 https://reactome.org/PathwayBrowser/#/R-DME-6805059 CK2:FACT phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-6805109 https://reactome.org/PathwayBrowser/#/R-DME-6805109 CDK2 phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-6805126 https://reactome.org/PathwayBrowser/#/R-DME-6805126 AURKB phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-6805276 https://reactome.org/PathwayBrowser/#/R-DME-6805276 CDK5 phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-6805399 https://reactome.org/PathwayBrowser/#/R-DME-6805399 TAF1 phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-6805470 https://reactome.org/PathwayBrowser/#/R-DME-6805470 AMPK phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-6805479 https://reactome.org/PathwayBrowser/#/R-DME-6805479 TP53RK phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-6805507 https://reactome.org/PathwayBrowser/#/R-DME-6805507 APAF1 binds AVEN IEA Drosophila melanogaster 456216 R-DME-6805640 https://reactome.org/PathwayBrowser/#/R-DME-6805640 AKT phosphorylates KAT6A IEA Drosophila melanogaster 456216 R-DME-6805785 https://reactome.org/PathwayBrowser/#/R-DME-6805785 AKT phosphorylates PHF20 IEA Drosophila melanogaster 456216 R-DME-6806877 https://reactome.org/PathwayBrowser/#/R-DME-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Drosophila melanogaster 456216 R-DME-6806967 https://reactome.org/PathwayBrowser/#/R-DME-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Drosophila melanogaster 456216 R-DME-6807868 https://reactome.org/PathwayBrowser/#/R-DME-6807868 GBF1 stimulates ARF nucleotide exchange IEA Drosophila melanogaster 456216 R-DME-6810233 https://reactome.org/PathwayBrowser/#/R-DME-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Drosophila melanogaster 456216 R-DME-6811522 https://reactome.org/PathwayBrowser/#/R-DME-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Drosophila melanogaster 456216 R-DME-6814119 https://reactome.org/PathwayBrowser/#/R-DME-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Drosophila melanogaster 456216 R-DME-6814120 https://reactome.org/PathwayBrowser/#/R-DME-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Drosophila melanogaster 456216 R-DME-6814121 https://reactome.org/PathwayBrowser/#/R-DME-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Drosophila melanogaster 456216 R-DME-6814124 https://reactome.org/PathwayBrowser/#/R-DME-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Drosophila melanogaster 456216 R-DME-6814409 https://reactome.org/PathwayBrowser/#/R-DME-6814409 CK2 phosphorylates PDCL IEA Drosophila melanogaster 456216 R-DME-6814670 https://reactome.org/PathwayBrowser/#/R-DME-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Drosophila melanogaster 456216 R-DME-6814678 https://reactome.org/PathwayBrowser/#/R-DME-6814678 ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN IEA Drosophila melanogaster 456216 R-DME-68944 https://reactome.org/PathwayBrowser/#/R-DME-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Drosophila melanogaster 456216 R-DME-69005 https://reactome.org/PathwayBrowser/#/R-DME-69005 Cdc6 protein is phosphorylated by CDK IEA Drosophila melanogaster 456216 R-DME-69063 https://reactome.org/PathwayBrowser/#/R-DME-69063 Loading of PCNA - Sliding Clamp Formation IEA Drosophila melanogaster 456216 R-DME-69195 https://reactome.org/PathwayBrowser/#/R-DME-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Drosophila melanogaster 456216 R-DME-69604 https://reactome.org/PathwayBrowser/#/R-DME-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Drosophila melanogaster 456216 R-DME-69608 https://reactome.org/PathwayBrowser/#/R-DME-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Drosophila melanogaster 456216 R-DME-69685 https://reactome.org/PathwayBrowser/#/R-DME-69685 CHEK2 phosphorylates TP53 IEA Drosophila melanogaster 456216 R-DME-70333 https://reactome.org/PathwayBrowser/#/R-DME-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Drosophila melanogaster 456216 R-DME-70420 https://reactome.org/PathwayBrowser/#/R-DME-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Drosophila melanogaster 456216 R-DME-70467 https://reactome.org/PathwayBrowser/#/R-DME-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Drosophila melanogaster 456216 R-DME-70486 https://reactome.org/PathwayBrowser/#/R-DME-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Drosophila melanogaster 456216 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 456216 R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Drosophila melanogaster 456216 R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Drosophila melanogaster 456216 R-DME-70606 https://reactome.org/PathwayBrowser/#/R-DME-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Drosophila melanogaster 456216 R-DME-70773 https://reactome.org/PathwayBrowser/#/R-DME-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Drosophila melanogaster 456216 R-DME-70967 https://reactome.org/PathwayBrowser/#/R-DME-70967 IDH3 complex decarboxylates isocitrate IEA Drosophila melanogaster 456216 R-DME-70997 https://reactome.org/PathwayBrowser/#/R-DME-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Drosophila melanogaster 456216 R-DME-71401 https://reactome.org/PathwayBrowser/#/R-DME-71401 OGDH dimer decarboxylates 2-OG IEA Drosophila melanogaster 456216 R-DME-71541 https://reactome.org/PathwayBrowser/#/R-DME-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Drosophila melanogaster 456216 R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 456216 R-DME-71802 https://reactome.org/PathwayBrowser/#/R-DME-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Drosophila melanogaster 456216 R-DME-71850 https://reactome.org/PathwayBrowser/#/R-DME-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Drosophila melanogaster 456216 R-DME-72621 https://reactome.org/PathwayBrowser/#/R-DME-72621 Ribosomal scanning IEA Drosophila melanogaster 456216 R-DME-73548 https://reactome.org/PathwayBrowser/#/R-DME-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Drosophila melanogaster 456216 R-DME-73577 https://reactome.org/PathwayBrowser/#/R-DME-73577 CAD hexamer transforms L-Gln to CAP IEA Drosophila melanogaster 456216 R-DME-73599 https://reactome.org/PathwayBrowser/#/R-DME-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Drosophila melanogaster 456216 R-DME-73635 https://reactome.org/PathwayBrowser/#/R-DME-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Drosophila melanogaster 456216 R-DME-73647 https://reactome.org/PathwayBrowser/#/R-DME-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Drosophila melanogaster 456216 R-DME-73788 https://reactome.org/PathwayBrowser/#/R-DME-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Drosophila melanogaster 456216 R-DME-73805 https://reactome.org/PathwayBrowser/#/R-DME-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Drosophila melanogaster 456216 R-DME-73810 https://reactome.org/PathwayBrowser/#/R-DME-73810 FGAM + ATP => AIR + ADP + Pi IEA Drosophila melanogaster 456216 R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 456216 R-DME-73814 https://reactome.org/PathwayBrowser/#/R-DME-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Drosophila melanogaster 456216 R-DME-74220 https://reactome.org/PathwayBrowser/#/R-DME-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Drosophila melanogaster 456216 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 456216 R-DME-75010 https://reactome.org/PathwayBrowser/#/R-DME-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Drosophila melanogaster 456216 R-DME-75125 https://reactome.org/PathwayBrowser/#/R-DME-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Drosophila melanogaster 456216 R-DME-75126 https://reactome.org/PathwayBrowser/#/R-DME-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Drosophila melanogaster 456216 R-DME-75809 https://reactome.org/PathwayBrowser/#/R-DME-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Drosophila melanogaster 456216 R-DME-75848 https://reactome.org/PathwayBrowser/#/R-DME-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Drosophila melanogaster 456216 R-DME-75851 https://reactome.org/PathwayBrowser/#/R-DME-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 456216 R-DME-75887 https://reactome.org/PathwayBrowser/#/R-DME-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Drosophila melanogaster 456216 R-DME-75949 https://reactome.org/PathwayBrowser/#/R-DME-75949 RNA Polymerase II Promoter Opening: First Transition IEA Drosophila melanogaster 456216 R-DME-77071 https://reactome.org/PathwayBrowser/#/R-DME-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Drosophila melanogaster 456216 R-DME-881988 https://reactome.org/PathwayBrowser/#/R-DME-881988 CRY is phosphorylated by SGG TAS Drosophila melanogaster 456216 R-DME-8847977 https://reactome.org/PathwayBrowser/#/R-DME-8847977 FRK phosphorylates PTEN IEA Drosophila melanogaster 456216 R-DME-8849353 https://reactome.org/PathwayBrowser/#/R-DME-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Drosophila melanogaster 456216 R-DME-8850527 https://reactome.org/PathwayBrowser/#/R-DME-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Drosophila melanogaster 456216 R-DME-8850529 https://reactome.org/PathwayBrowser/#/R-DME-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Drosophila melanogaster 456216 R-DME-8850534 https://reactome.org/PathwayBrowser/#/R-DME-8850534 PDCL promotes G-protein beta 5 folding IEA Drosophila melanogaster 456216 R-DME-8850539 https://reactome.org/PathwayBrowser/#/R-DME-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Drosophila melanogaster 456216 R-DME-8850945 https://reactome.org/PathwayBrowser/#/R-DME-8850945 Casein kinase II phosphorylates PTEN IEA Drosophila melanogaster 456216 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 456216 R-DME-8851797 https://reactome.org/PathwayBrowser/#/R-DME-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Drosophila melanogaster 456216 R-DME-8853774 https://reactome.org/PathwayBrowser/#/R-DME-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Drosophila melanogaster 456216 R-DME-8856813 https://reactome.org/PathwayBrowser/#/R-DME-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Drosophila melanogaster 456216 R-DME-8857925 https://reactome.org/PathwayBrowser/#/R-DME-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Drosophila melanogaster 456216 R-DME-8867041 https://reactome.org/PathwayBrowser/#/R-DME-8867041 EGFR phosphorylates EPS15 IEA Drosophila melanogaster 456216 R-DME-8868066 https://reactome.org/PathwayBrowser/#/R-DME-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Drosophila melanogaster 456216 R-DME-8868072 https://reactome.org/PathwayBrowser/#/R-DME-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Drosophila melanogaster 456216 R-DME-8868118 https://reactome.org/PathwayBrowser/#/R-DME-8868118 MAPK12 phosphorylates PTPN3 IEA Drosophila melanogaster 456216 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster 456216 R-DME-8869606 https://reactome.org/PathwayBrowser/#/R-DME-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 456216 R-DME-8869607 https://reactome.org/PathwayBrowser/#/R-DME-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 456216 R-DME-8869627 https://reactome.org/PathwayBrowser/#/R-DME-8869627 NMRK2 phosphorylates NR to yield NMN IEA Drosophila melanogaster 456216 R-DME-8869633 https://reactome.org/PathwayBrowser/#/R-DME-8869633 NMRK1 phosphorylates NR to yield NMN IEA Drosophila melanogaster 456216 R-DME-8871373 https://reactome.org/PathwayBrowser/#/R-DME-8871373 BMX phosphorylates RUFY1 IEA Drosophila melanogaster 456216 R-DME-8876889 https://reactome.org/PathwayBrowser/#/R-DME-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 456216 R-DME-8877691 https://reactome.org/PathwayBrowser/#/R-DME-8877691 MAP2K6 phosphorylates PIP4K2B IEA Drosophila melanogaster 456216 R-DME-8878050 https://reactome.org/PathwayBrowser/#/R-DME-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Drosophila melanogaster 456216 R-DME-8878054 https://reactome.org/PathwayBrowser/#/R-DME-8878054 HIPK2 phosphorylates RUNX1 IEA Drosophila melanogaster 456216 R-DME-8933446 https://reactome.org/PathwayBrowser/#/R-DME-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Drosophila melanogaster 456216 R-DME-8934446 https://reactome.org/PathwayBrowser/#/R-DME-8934446 Activated PKC phosphorylates SHC1 IEA Drosophila melanogaster 456216 R-DME-8937807 https://reactome.org/PathwayBrowser/#/R-DME-8937807 SRC phosphorylates RUNX3 IEA Drosophila melanogaster 456216 R-DME-8942607 https://reactome.org/PathwayBrowser/#/R-DME-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Drosophila melanogaster 456216 R-DME-8942836 https://reactome.org/PathwayBrowser/#/R-DME-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Drosophila melanogaster 456216 R-DME-8944454 https://reactome.org/PathwayBrowser/#/R-DME-8944454 mTORC1 phosphorylates MAF1 IEA Drosophila melanogaster 456216 R-DME-8948039 https://reactome.org/PathwayBrowser/#/R-DME-8948039 FUNDC1 is phosphorylated by CK2 IEA Drosophila melanogaster 456216 R-DME-8948143 https://reactome.org/PathwayBrowser/#/R-DME-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Drosophila melanogaster 456216 R-DME-8948146 https://reactome.org/PathwayBrowser/#/R-DME-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Drosophila melanogaster 456216 R-DME-8948757 https://reactome.org/PathwayBrowser/#/R-DME-8948757 AKT phosphorylates MKRN1 IEA Drosophila melanogaster 456216 R-DME-8952289 https://reactome.org/PathwayBrowser/#/R-DME-8952289 FAM20C phosphorylates FAM20C substrates IEA Drosophila melanogaster 456216 R-DME-8954327 https://reactome.org/PathwayBrowser/#/R-DME-8954327 UCKL1 phosphorylates urindine, cytidine IEA Drosophila melanogaster 456216 R-DME-8955030 https://reactome.org/PathwayBrowser/#/R-DME-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 456216 R-DME-8955844 https://reactome.org/PathwayBrowser/#/R-DME-8955844 RBKS phosphorylates ribose to R5P IEA Drosophila melanogaster 456216 R-DME-8964242 https://reactome.org/PathwayBrowser/#/R-DME-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Drosophila melanogaster 456216 R-DME-9007539 https://reactome.org/PathwayBrowser/#/R-DME-9007539 CHEK1 phosphorylates E2F6 IEA Drosophila melanogaster 456216 R-DME-9008043 https://reactome.org/PathwayBrowser/#/R-DME-9008043 MAPK8 phosphorylation IEA Drosophila melanogaster 456216 R-DME-9008412 https://reactome.org/PathwayBrowser/#/R-DME-9008412 CDK4 phosphorylates RUNX2 IEA Drosophila melanogaster 456216 R-DME-9008684 https://reactome.org/PathwayBrowser/#/R-DME-9008684 TBK1 phosphorylation IEA Drosophila melanogaster 456216 R-DME-9009072 https://reactome.org/PathwayBrowser/#/R-DME-9009072 STAT3 phosphorylation IEA Drosophila melanogaster 456216 R-DME-9009282 https://reactome.org/PathwayBrowser/#/R-DME-9009282 CDK1 phosphorylates RUNX2 IEA Drosophila melanogaster 456216 R-DME-9012319 https://reactome.org/PathwayBrowser/#/R-DME-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Drosophila melanogaster 456216 R-DME-9021609 https://reactome.org/PathwayBrowser/#/R-DME-9021609 ESR-associated SRC autophosphorylates IEA Drosophila melanogaster 456216 R-DME-9021627 https://reactome.org/PathwayBrowser/#/R-DME-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 456216 R-DME-9038161 https://reactome.org/PathwayBrowser/#/R-DME-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Drosophila melanogaster 456216 R-DME-913996 https://reactome.org/PathwayBrowser/#/R-DME-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Drosophila melanogaster 456216 R-DME-917693 https://reactome.org/PathwayBrowser/#/R-DME-917693 ESCRT Disassembly IEA Drosophila melanogaster 456216 R-DME-917841 https://reactome.org/PathwayBrowser/#/R-DME-917841 Acidification of Tf:TfR1 containing endosome IEA Drosophila melanogaster 456216 R-DME-917979 https://reactome.org/PathwayBrowser/#/R-DME-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Drosophila melanogaster 456216 R-DME-927889 https://reactome.org/PathwayBrowser/#/R-DME-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Drosophila melanogaster 456216 R-DME-934559 https://reactome.org/PathwayBrowser/#/R-DME-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Drosophila melanogaster 456216 R-DME-936883 https://reactome.org/PathwayBrowser/#/R-DME-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Drosophila melanogaster 456216 R-DME-936895 https://reactome.org/PathwayBrowser/#/R-DME-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Drosophila melanogaster 456216 R-DME-937034 https://reactome.org/PathwayBrowser/#/R-DME-937034 IRAK1 phosphorylates Pellino IEA Drosophila melanogaster 456216 R-DME-939763 https://reactome.org/PathwayBrowser/#/R-DME-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Drosophila melanogaster 456216 R-DME-947591 https://reactome.org/PathwayBrowser/#/R-DME-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Drosophila melanogaster 456216 R-DME-9604328 https://reactome.org/PathwayBrowser/#/R-DME-9604328 AKT1 phosphorylates NOTCH4 IEA Drosophila melanogaster 456216 R-DME-9610153 https://reactome.org/PathwayBrowser/#/R-DME-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Drosophila melanogaster 456216 R-DME-9610156 https://reactome.org/PathwayBrowser/#/R-DME-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Drosophila melanogaster 456216 R-DME-9610163 https://reactome.org/PathwayBrowser/#/R-DME-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Drosophila melanogaster 456216 R-DME-9624526 https://reactome.org/PathwayBrowser/#/R-DME-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Drosophila melanogaster 456216 R-DME-9627089 https://reactome.org/PathwayBrowser/#/R-DME-9627089 CASP9 is phosphorylated at T412 IEA Drosophila melanogaster 456216 R-DME-9632858 https://reactome.org/PathwayBrowser/#/R-DME-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Drosophila melanogaster 456216 R-DME-964958 https://reactome.org/PathwayBrowser/#/R-DME-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Drosophila melanogaster 456216 R-DME-964962 https://reactome.org/PathwayBrowser/#/R-DME-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Drosophila melanogaster 456216 R-DME-964970 https://reactome.org/PathwayBrowser/#/R-DME-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Drosophila melanogaster 456216 R-DME-9650858 https://reactome.org/PathwayBrowser/#/R-DME-9650858 Meglitinides bind ABCC8 IEA Drosophila melanogaster 456216 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 456216 R-DME-9653503 https://reactome.org/PathwayBrowser/#/R-DME-9653503 KRAS4B is phosphorylated on serine 181 IEA Drosophila melanogaster 456216 R-DME-9661417 https://reactome.org/PathwayBrowser/#/R-DME-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 456216 R-DME-9684118 https://reactome.org/PathwayBrowser/#/R-DME-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Drosophila melanogaster 456216 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 456216 R-DME-9699579 https://reactome.org/PathwayBrowser/#/R-DME-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Drosophila melanogaster 456216 R-DME-9706399 https://reactome.org/PathwayBrowser/#/R-DME-9706399 RHOBTB3 hydrolyzes ATP IEA Drosophila melanogaster 456216 R-DME-9731111 https://reactome.org/PathwayBrowser/#/R-DME-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Drosophila melanogaster 456216 R-DME-9734547 https://reactome.org/PathwayBrowser/#/R-DME-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Drosophila melanogaster 456216 R-DME-9734687 https://reactome.org/PathwayBrowser/#/R-DME-9734687 ORC6 is phosphorylated on T195 IEA Drosophila melanogaster 456216 R-DME-9748949 https://reactome.org/PathwayBrowser/#/R-DME-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Drosophila melanogaster 456216 R-DME-9748963 https://reactome.org/PathwayBrowser/#/R-DME-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Drosophila melanogaster 456216 R-DME-9748969 https://reactome.org/PathwayBrowser/#/R-DME-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Drosophila melanogaster 456216 R-DME-9748999 https://reactome.org/PathwayBrowser/#/R-DME-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Drosophila melanogaster 456216 R-DME-9750546 https://reactome.org/PathwayBrowser/#/R-DME-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Drosophila melanogaster 456216 R-DME-9750656 https://reactome.org/PathwayBrowser/#/R-DME-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Drosophila melanogaster 456216 R-DME-975139 https://reactome.org/PathwayBrowser/#/R-DME-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Drosophila melanogaster 456216 R-DME-9753278 https://reactome.org/PathwayBrowser/#/R-DME-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 456216 R-DME-9753283 https://reactome.org/PathwayBrowser/#/R-DME-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 456216 R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 456216 R-DME-9754974 https://reactome.org/PathwayBrowser/#/R-DME-9754974 ADK phosphorylates RBV IEA Drosophila melanogaster 456216 R-DME-9755013 https://reactome.org/PathwayBrowser/#/R-DME-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Drosophila melanogaster 456216 R-DME-9760094 https://reactome.org/PathwayBrowser/#/R-DME-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Drosophila melanogaster 456216 R-DME-9762094 https://reactome.org/PathwayBrowser/#/R-DME-9762094 GSK3B phosphorylates p-NFE2L2 IEA Drosophila melanogaster 456216 R-DME-9770141 https://reactome.org/PathwayBrowser/#/R-DME-9770141 Formation of the Spliceosomal C* complex IEA Drosophila melanogaster 456216 R-DME-9773803 https://reactome.org/PathwayBrowser/#/R-DME-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Drosophila melanogaster 456216 R-DME-9794120 https://reactome.org/PathwayBrowser/#/R-DME-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Drosophila melanogaster 456216 R-DME-9794572 https://reactome.org/PathwayBrowser/#/R-DME-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Drosophila melanogaster 456216 R-DME-9796053 https://reactome.org/PathwayBrowser/#/R-DME-9796053 PRKCI phosphorylates NFE2L2 IEA Drosophila melanogaster 456216 R-DME-9796067 https://reactome.org/PathwayBrowser/#/R-DME-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Drosophila melanogaster 456216 R-DME-9824977 https://reactome.org/PathwayBrowser/#/R-DME-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Drosophila melanogaster 456216 R-DME-9824994 https://reactome.org/PathwayBrowser/#/R-DME-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Drosophila melanogaster 456216 R-DME-9824995 https://reactome.org/PathwayBrowser/#/R-DME-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Drosophila melanogaster 456216 R-DME-9824999 https://reactome.org/PathwayBrowser/#/R-DME-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Drosophila melanogaster 456216 R-DME-9825759 https://reactome.org/PathwayBrowser/#/R-DME-9825759 MAPK-dependent phosphorylation of KARS IEA Drosophila melanogaster 456216 R-DME-983259 https://reactome.org/PathwayBrowser/#/R-DME-983259 Kinesins move along microtubules consuming ATP IEA Drosophila melanogaster 456216 R-DME-9836159 https://reactome.org/PathwayBrowser/#/R-DME-9836159 p-PKR dimer phosphorylates DHX9 IEA Drosophila melanogaster 456216 R-DME-9836184 https://reactome.org/PathwayBrowser/#/R-DME-9836184 p-PKR dimer phosphorylates CDK1 IEA Drosophila melanogaster 456216 R-DME-9836322 https://reactome.org/PathwayBrowser/#/R-DME-9836322 p-PKR dimer phosphorylates MKK6 IEA Drosophila melanogaster 456216 R-DME-9836362 https://reactome.org/PathwayBrowser/#/R-DME-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Drosophila melanogaster 456216 R-DME-9836383 https://reactome.org/PathwayBrowser/#/R-DME-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Drosophila melanogaster 456216 R-DME-9836515 https://reactome.org/PathwayBrowser/#/R-DME-9836515 p-PKR dimer phosphorylates PTPN2 IEA Drosophila melanogaster 456216 R-DME-9836617 https://reactome.org/PathwayBrowser/#/R-DME-9836617 p-PKR dimer phosphorylates SPHK1 IEA Drosophila melanogaster 456216 R-DME-9836664 https://reactome.org/PathwayBrowser/#/R-DME-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Drosophila melanogaster 456216 R-DME-9837333 https://reactome.org/PathwayBrowser/#/R-DME-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Drosophila melanogaster 456216 R-DME-9837337 https://reactome.org/PathwayBrowser/#/R-DME-9837337 DCAKD phosphorylates DP-CoA IEA Drosophila melanogaster 456216 R-DME-9838004 https://reactome.org/PathwayBrowser/#/R-DME-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Drosophila melanogaster 456216 R-DME-9838081 https://reactome.org/PathwayBrowser/#/R-DME-9838081 LONP1 degrades mitochondrial matrix proteins IEA Drosophila melanogaster 456216 R-DME-9838289 https://reactome.org/PathwayBrowser/#/R-DME-9838289 CLPXP degrades mitochondrial matrix proteins IEA Drosophila melanogaster 456216 R-DME-9838321 https://reactome.org/PathwayBrowser/#/R-DME-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Drosophila melanogaster 456216 R-DME-9839059 https://reactome.org/PathwayBrowser/#/R-DME-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Drosophila melanogaster 456216 R-DME-9839105 https://reactome.org/PathwayBrowser/#/R-DME-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Drosophila melanogaster 456216 R-DME-9839113 https://reactome.org/PathwayBrowser/#/R-DME-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Drosophila melanogaster 456216 R-DME-9843721 https://reactome.org/PathwayBrowser/#/R-DME-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Drosophila melanogaster 456216 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 456216 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 456216 R-DRE-109415 https://reactome.org/PathwayBrowser/#/R-DRE-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Danio rerio 456216 R-DRE-109624 https://reactome.org/PathwayBrowser/#/R-DRE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Danio rerio 456216 R-DRE-109671 https://reactome.org/PathwayBrowser/#/R-DRE-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Danio rerio 456216 R-DRE-109702 https://reactome.org/PathwayBrowser/#/R-DRE-109702 PDPK1 phosphorylates AKT2 IEA Danio rerio 456216 R-DRE-109860 https://reactome.org/PathwayBrowser/#/R-DRE-109860 MAP2K1 phosphorylates MAPK3 IEA Danio rerio 456216 R-DRE-109862 https://reactome.org/PathwayBrowser/#/R-DRE-109862 MAP2K2 phosphorylates MAPK1 IEA Danio rerio 456216 R-DRE-109903 https://reactome.org/PathwayBrowser/#/R-DRE-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Danio rerio 456216 R-DRE-110133 https://reactome.org/PathwayBrowser/#/R-DRE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Danio rerio 456216 R-DRE-110137 https://reactome.org/PathwayBrowser/#/R-DRE-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Danio rerio 456216 R-DRE-110138 https://reactome.org/PathwayBrowser/#/R-DRE-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 456216 R-DRE-110144 https://reactome.org/PathwayBrowser/#/R-DRE-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Danio rerio 456216 R-DRE-110145 https://reactome.org/PathwayBrowser/#/R-DRE-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Danio rerio 456216 R-DRE-1112510 https://reactome.org/PathwayBrowser/#/R-DRE-1112510 IL6ST is tyrosine phosphorylated IEA Danio rerio 456216 R-DRE-1112514 https://reactome.org/PathwayBrowser/#/R-DRE-1112514 JAK activation IEA Danio rerio 456216 R-DRE-1112602 https://reactome.org/PathwayBrowser/#/R-DRE-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Danio rerio 456216 R-DRE-1112703 https://reactome.org/PathwayBrowser/#/R-DRE-1112703 PTPN11 is phosphorylated IEA Danio rerio 456216 R-DRE-1112727 https://reactome.org/PathwayBrowser/#/R-DRE-1112727 Serine phosphorylation of STATs IEA Danio rerio 456216 R-DRE-111898 https://reactome.org/PathwayBrowser/#/R-DRE-111898 Phosphorylation of cPLA2 by ERK-2 IEA Danio rerio 456216 R-DRE-112342 https://reactome.org/PathwayBrowser/#/R-DRE-112342 Inactivation of MAP2K1 by CDK1 IEA Danio rerio 456216 R-DRE-114252 https://reactome.org/PathwayBrowser/#/R-DRE-114252 Cleavage of Procaspase-3 by the apoptosome IEA Danio rerio 456216 R-DRE-114254 https://reactome.org/PathwayBrowser/#/R-DRE-114254 CYCS binds to APAF1 IEA Danio rerio 456216 R-DRE-114259 https://reactome.org/PathwayBrowser/#/R-DRE-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Danio rerio 456216 R-DRE-114261 https://reactome.org/PathwayBrowser/#/R-DRE-114261 Cleavage of Procaspase-7 by the apoptosome IEA Danio rerio 456216 R-DRE-114684 https://reactome.org/PathwayBrowser/#/R-DRE-114684 Phosphorylation of Syntaxin-4 IEA Danio rerio 456216 R-DRE-1168459 https://reactome.org/PathwayBrowser/#/R-DRE-1168459 Lyn activates ERK IEA Danio rerio 456216 R-DRE-1181149 https://reactome.org/PathwayBrowser/#/R-DRE-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Danio rerio 456216 R-DRE-1247935 https://reactome.org/PathwayBrowser/#/R-DRE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Danio rerio 456216 R-DRE-1247960 https://reactome.org/PathwayBrowser/#/R-DRE-1247960 Activation of p38 MAPK IEA Danio rerio 456216 R-DRE-1250195 https://reactome.org/PathwayBrowser/#/R-DRE-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Danio rerio 456216 R-DRE-1250315 https://reactome.org/PathwayBrowser/#/R-DRE-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Danio rerio 456216 R-DRE-1250370 https://reactome.org/PathwayBrowser/#/R-DRE-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Danio rerio 456216 R-DRE-1250462 https://reactome.org/PathwayBrowser/#/R-DRE-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Danio rerio 456216 R-DRE-1295609 https://reactome.org/PathwayBrowser/#/R-DRE-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Danio rerio 456216 R-DRE-1306979 https://reactome.org/PathwayBrowser/#/R-DRE-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Danio rerio 456216 R-DRE-1362270 https://reactome.org/PathwayBrowser/#/R-DRE-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Danio rerio 456216 R-DRE-1433418 https://reactome.org/PathwayBrowser/#/R-DRE-1433418 Phosphorylation of JAK2 IEA Danio rerio 456216 R-DRE-1433488 https://reactome.org/PathwayBrowser/#/R-DRE-1433488 Phosphorylation of SHP2 by SFKs IEA Danio rerio 456216 R-DRE-1433506 https://reactome.org/PathwayBrowser/#/R-DRE-1433506 Phosphorylation of APS IEA Danio rerio 456216 R-DRE-1433514 https://reactome.org/PathwayBrowser/#/R-DRE-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Danio rerio 456216 R-DRE-1454916 https://reactome.org/PathwayBrowser/#/R-DRE-1454916 The ABCC family mediates organic anion transport IEA Danio rerio 456216 R-DRE-1454928 https://reactome.org/PathwayBrowser/#/R-DRE-1454928 ABCG4 may mediate cholesterol efflux IEA Danio rerio 456216 R-DRE-1470009 https://reactome.org/PathwayBrowser/#/R-DRE-1470009 Phosphorylation of STATs IEA Danio rerio 456216 R-DRE-1472121 https://reactome.org/PathwayBrowser/#/R-DRE-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Danio rerio 456216 R-DRE-1483004 https://reactome.org/PathwayBrowser/#/R-DRE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Danio rerio 456216 R-DRE-1483222 https://reactome.org/PathwayBrowser/#/R-DRE-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Danio rerio 456216 R-DRE-1524186 https://reactome.org/PathwayBrowser/#/R-DRE-1524186 Phosphorylation of PLCgamma by PDGFR IEA Danio rerio 456216 R-DRE-1549526 https://reactome.org/PathwayBrowser/#/R-DRE-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Danio rerio 456216 R-DRE-156682 https://reactome.org/PathwayBrowser/#/R-DRE-156682 PLK1 phosphorylates NUDC IEA Danio rerio 456216 R-DRE-156699 https://reactome.org/PathwayBrowser/#/R-DRE-156699 Inactivation of Wee1 kinase IEA Danio rerio 456216 R-DRE-156723 https://reactome.org/PathwayBrowser/#/R-DRE-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Danio rerio 456216 R-DRE-162657 https://reactome.org/PathwayBrowser/#/R-DRE-162657 Inactivation of Myt1 kinase IEA Danio rerio 456216 R-DRE-163010 https://reactome.org/PathwayBrowser/#/R-DRE-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Danio rerio 456216 R-DRE-163215 https://reactome.org/PathwayBrowser/#/R-DRE-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Danio rerio 456216 R-DRE-164832 https://reactome.org/PathwayBrowser/#/R-DRE-164832 ATPase synthesizes ATP IEA Danio rerio 456216 R-DRE-164840 https://reactome.org/PathwayBrowser/#/R-DRE-164840 ADP and Pi bind to ATPase IEA Danio rerio 456216 R-DRE-165692 https://reactome.org/PathwayBrowser/#/R-DRE-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Danio rerio 456216 R-DRE-165718 https://reactome.org/PathwayBrowser/#/R-DRE-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Danio rerio 456216 R-DRE-165726 https://reactome.org/PathwayBrowser/#/R-DRE-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Danio rerio 456216 R-DRE-1675773 https://reactome.org/PathwayBrowser/#/R-DRE-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Danio rerio 456216 R-DRE-1675776 https://reactome.org/PathwayBrowser/#/R-DRE-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Danio rerio 456216 R-DRE-1675780 https://reactome.org/PathwayBrowser/#/R-DRE-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Danio rerio 456216 R-DRE-1675810 https://reactome.org/PathwayBrowser/#/R-DRE-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Danio rerio 456216 R-DRE-1675813 https://reactome.org/PathwayBrowser/#/R-DRE-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Danio rerio 456216 R-DRE-1675883 https://reactome.org/PathwayBrowser/#/R-DRE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Danio rerio 456216 R-DRE-1675974 https://reactome.org/PathwayBrowser/#/R-DRE-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Danio rerio 456216 R-DRE-1676048 https://reactome.org/PathwayBrowser/#/R-DRE-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Danio rerio 456216 R-DRE-1676082 https://reactome.org/PathwayBrowser/#/R-DRE-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Danio rerio 456216 R-DRE-1676109 https://reactome.org/PathwayBrowser/#/R-DRE-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Danio rerio 456216 R-DRE-1676134 https://reactome.org/PathwayBrowser/#/R-DRE-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Danio rerio 456216 R-DRE-1676145 https://reactome.org/PathwayBrowser/#/R-DRE-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Danio rerio 456216 R-DRE-1676185 https://reactome.org/PathwayBrowser/#/R-DRE-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Danio rerio 456216 R-DRE-168136 https://reactome.org/PathwayBrowser/#/R-DRE-168136 Activated JNKs phosphorylate c-JUN IEA Danio rerio 456216 R-DRE-168162 https://reactome.org/PathwayBrowser/#/R-DRE-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Danio rerio 456216 R-DRE-169905 https://reactome.org/PathwayBrowser/#/R-DRE-169905 ARMS is phosphorylated by active TrkA receptor IEA Danio rerio 456216 R-DRE-170026 https://reactome.org/PathwayBrowser/#/R-DRE-170026 Protons are translocated from the intermembrane space to the matrix IEA Danio rerio 456216 R-DRE-170055 https://reactome.org/PathwayBrowser/#/R-DRE-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Danio rerio 456216 R-DRE-170070 https://reactome.org/PathwayBrowser/#/R-DRE-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Danio rerio 456216 R-DRE-170126 https://reactome.org/PathwayBrowser/#/R-DRE-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Danio rerio 456216 R-DRE-170843 https://reactome.org/PathwayBrowser/#/R-DRE-170843 TGFBR2 phosphorylates TGFBR1 IEA Danio rerio 456216 R-DRE-170868 https://reactome.org/PathwayBrowser/#/R-DRE-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Danio rerio 456216 R-DRE-174122 https://reactome.org/PathwayBrowser/#/R-DRE-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Danio rerio 456216 R-DRE-174164 https://reactome.org/PathwayBrowser/#/R-DRE-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Danio rerio 456216 R-DRE-174174 https://reactome.org/PathwayBrowser/#/R-DRE-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Danio rerio 456216 R-DRE-174251 https://reactome.org/PathwayBrowser/#/R-DRE-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Danio rerio 456216 R-DRE-174389 https://reactome.org/PathwayBrowser/#/R-DRE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Danio rerio 456216 R-DRE-174394 https://reactome.org/PathwayBrowser/#/R-DRE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Danio rerio 456216 R-DRE-177930 https://reactome.org/PathwayBrowser/#/R-DRE-177930 GAB1 phosphorylation by EGFR kinase IEA Danio rerio 456216 R-DRE-177934 https://reactome.org/PathwayBrowser/#/R-DRE-177934 EGFR autophosphorylation IEA Danio rerio 456216 R-DRE-177937 https://reactome.org/PathwayBrowser/#/R-DRE-177937 Phosphorylation of EGFR by SRC kinase IEA Danio rerio 456216 R-DRE-177939 https://reactome.org/PathwayBrowser/#/R-DRE-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Danio rerio 456216 R-DRE-182969 https://reactome.org/PathwayBrowser/#/R-DRE-182969 Phosphorylation of CBL (EGFR:CBL) IEA Danio rerio 456216 R-DRE-183058 https://reactome.org/PathwayBrowser/#/R-DRE-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Danio rerio 456216 R-DRE-1855157 https://reactome.org/PathwayBrowser/#/R-DRE-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Danio rerio 456216 R-DRE-1855158 https://reactome.org/PathwayBrowser/#/R-DRE-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Danio rerio 456216 R-DRE-1855162 https://reactome.org/PathwayBrowser/#/R-DRE-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Danio rerio 456216 R-DRE-1855169 https://reactome.org/PathwayBrowser/#/R-DRE-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Danio rerio 456216 R-DRE-1855172 https://reactome.org/PathwayBrowser/#/R-DRE-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Danio rerio 456216 R-DRE-1855176 https://reactome.org/PathwayBrowser/#/R-DRE-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Danio rerio 456216 R-DRE-1855179 https://reactome.org/PathwayBrowser/#/R-DRE-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Danio rerio 456216 R-DRE-1855181 https://reactome.org/PathwayBrowser/#/R-DRE-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Danio rerio 456216 R-DRE-1855185 https://reactome.org/PathwayBrowser/#/R-DRE-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 456216 R-DRE-1855193 https://reactome.org/PathwayBrowser/#/R-DRE-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Danio rerio 456216 R-DRE-1855194 https://reactome.org/PathwayBrowser/#/R-DRE-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Danio rerio 456216 R-DRE-1855197 https://reactome.org/PathwayBrowser/#/R-DRE-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Danio rerio 456216 R-DRE-1855206 https://reactome.org/PathwayBrowser/#/R-DRE-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 456216 R-DRE-1855207 https://reactome.org/PathwayBrowser/#/R-DRE-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Danio rerio 456216 R-DRE-1855223 https://reactome.org/PathwayBrowser/#/R-DRE-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Danio rerio 456216 R-DRE-1855224 https://reactome.org/PathwayBrowser/#/R-DRE-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Danio rerio 456216 R-DRE-1855227 https://reactome.org/PathwayBrowser/#/R-DRE-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Danio rerio 456216 R-DRE-1855228 https://reactome.org/PathwayBrowser/#/R-DRE-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 456216 R-DRE-1855230 https://reactome.org/PathwayBrowser/#/R-DRE-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Danio rerio 456216 R-DRE-1855233 https://reactome.org/PathwayBrowser/#/R-DRE-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Danio rerio 456216 R-DRE-186800 https://reactome.org/PathwayBrowser/#/R-DRE-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Danio rerio 456216 R-DRE-187520 https://reactome.org/PathwayBrowser/#/R-DRE-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Danio rerio 456216 R-DRE-187688 https://reactome.org/PathwayBrowser/#/R-DRE-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Danio rerio 456216 R-DRE-187916 https://reactome.org/PathwayBrowser/#/R-DRE-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Danio rerio 456216 R-DRE-187948 https://reactome.org/PathwayBrowser/#/R-DRE-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Danio rerio 456216 R-DRE-188390 https://reactome.org/PathwayBrowser/#/R-DRE-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Danio rerio 456216 R-DRE-190326 https://reactome.org/PathwayBrowser/#/R-DRE-190326 Autocatalytic phosphorylation of FGFR4 IEA Danio rerio 456216 R-DRE-190385 https://reactome.org/PathwayBrowser/#/R-DRE-190385 Autocatalytic phosphorylation of FGFR3b IEA Danio rerio 456216 R-DRE-190388 https://reactome.org/PathwayBrowser/#/R-DRE-190388 Autocatalytic phosphorylation of FGFR3c IEA Danio rerio 456216 R-DRE-190408 https://reactome.org/PathwayBrowser/#/R-DRE-190408 Autocatalytic phosphorylation of FGFR2b IEA Danio rerio 456216 R-DRE-190413 https://reactome.org/PathwayBrowser/#/R-DRE-190413 Autocatalytic phosphorylation of FGFR2c IEA Danio rerio 456216 R-DRE-190427 https://reactome.org/PathwayBrowser/#/R-DRE-190427 Autocatalytic phosphorylation of FGFR1b IEA Danio rerio 456216 R-DRE-190429 https://reactome.org/PathwayBrowser/#/R-DRE-190429 Autocatalytic phosphorylation of FGFR1c IEA Danio rerio 456216 R-DRE-191062 https://reactome.org/PathwayBrowser/#/R-DRE-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Danio rerio 456216 R-DRE-191380 https://reactome.org/PathwayBrowser/#/R-DRE-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Danio rerio 456216 R-DRE-191414 https://reactome.org/PathwayBrowser/#/R-DRE-191414 MVD decarboxylates MVA5PP to IPPP IEA Danio rerio 456216 R-DRE-191422 https://reactome.org/PathwayBrowser/#/R-DRE-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Danio rerio 456216 R-DRE-1963581 https://reactome.org/PathwayBrowser/#/R-DRE-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Danio rerio 456216 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 456216 R-DRE-1963586 https://reactome.org/PathwayBrowser/#/R-DRE-1963586 SRC family kinases phosphorylate ERBB2 IEA Danio rerio 456216 R-DRE-196773 https://reactome.org/PathwayBrowser/#/R-DRE-196773 COASY phosphorylates DP-CoA IEA Danio rerio 456216 R-DRE-197198 https://reactome.org/PathwayBrowser/#/R-DRE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Danio rerio 456216 R-DRE-197958 https://reactome.org/PathwayBrowser/#/R-DRE-197958 FPGS-2 transforms THF to THFPG IEA Danio rerio 456216 R-DRE-198314 https://reactome.org/PathwayBrowser/#/R-DRE-198314 DAG stimulates protein kinase C-delta IEA Danio rerio 456216 R-DRE-198599 https://reactome.org/PathwayBrowser/#/R-DRE-198599 AKT phosphorylates MDM2 IEA Danio rerio 456216 R-DRE-198611 https://reactome.org/PathwayBrowser/#/R-DRE-198611 AKT phosphorylates IKKalpha IEA Danio rerio 456216 R-DRE-198613 https://reactome.org/PathwayBrowser/#/R-DRE-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Danio rerio 456216 R-DRE-198621 https://reactome.org/PathwayBrowser/#/R-DRE-198621 AKT phosphorylates caspase-9 IEA Danio rerio 456216 R-DRE-199203 https://reactome.org/PathwayBrowser/#/R-DRE-199203 PANK1/3 phosphorylate PanK IEA Danio rerio 456216 R-DRE-199298 https://reactome.org/PathwayBrowser/#/R-DRE-199298 AKT phosphorylates CREB1 IEA Danio rerio 456216 R-DRE-199299 https://reactome.org/PathwayBrowser/#/R-DRE-199299 AKT phosphorylates FOXO transcription factors IEA Danio rerio 456216 R-DRE-199863 https://reactome.org/PathwayBrowser/#/R-DRE-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Danio rerio 456216 R-DRE-199917 https://reactome.org/PathwayBrowser/#/R-DRE-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Danio rerio 456216 R-DRE-200318 https://reactome.org/PathwayBrowser/#/R-DRE-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Danio rerio 456216 R-DRE-200326 https://reactome.org/PathwayBrowser/#/R-DRE-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Danio rerio 456216 R-DRE-200681 https://reactome.org/PathwayBrowser/#/R-DRE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Danio rerio 456216 R-DRE-200682 https://reactome.org/PathwayBrowser/#/R-DRE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Danio rerio 456216 R-DRE-200711 https://reactome.org/PathwayBrowser/#/R-DRE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Danio rerio 456216 R-DRE-201443 https://reactome.org/PathwayBrowser/#/R-DRE-201443 Type II receptor phosphorylates type I receptor IEA Danio rerio 456216 R-DRE-201476 https://reactome.org/PathwayBrowser/#/R-DRE-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Danio rerio 456216 R-DRE-201510 https://reactome.org/PathwayBrowser/#/R-DRE-201510 PI3K synthesizes PIP3 downstream of ALK IEA Danio rerio 456216 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 456216 R-DRE-201677 https://reactome.org/PathwayBrowser/#/R-DRE-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Danio rerio 456216 R-DRE-2028583 https://reactome.org/PathwayBrowser/#/R-DRE-2028583 Phosphorylation of YAP by LATS2 IEA Danio rerio 456216 R-DRE-2028589 https://reactome.org/PathwayBrowser/#/R-DRE-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Danio rerio 456216 R-DRE-2028591 https://reactome.org/PathwayBrowser/#/R-DRE-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Danio rerio 456216 R-DRE-2028598 https://reactome.org/PathwayBrowser/#/R-DRE-2028598 Phosphorylation of YAP by LATS1 IEA Danio rerio 456216 R-DRE-2028635 https://reactome.org/PathwayBrowser/#/R-DRE-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Danio rerio 456216 R-DRE-2028661 https://reactome.org/PathwayBrowser/#/R-DRE-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Danio rerio 456216 R-DRE-2028673 https://reactome.org/PathwayBrowser/#/R-DRE-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Danio rerio 456216 R-DRE-2028675 https://reactome.org/PathwayBrowser/#/R-DRE-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Danio rerio 456216 R-DRE-2029473 https://reactome.org/PathwayBrowser/#/R-DRE-2029473 Branching and elongation of mother and daughter filaments IEA Danio rerio 456216 R-DRE-205136 https://reactome.org/PathwayBrowser/#/R-DRE-205136 GTP-bound RAC contributes to JNK activation IEA Danio rerio 456216 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 456216 R-DRE-2060328 https://reactome.org/PathwayBrowser/#/R-DRE-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Danio rerio 456216 R-DRE-211164 https://reactome.org/PathwayBrowser/#/R-DRE-211164 AKT phosphorylates FOXO1A IEA Danio rerio 456216 R-DRE-212710 https://reactome.org/PathwayBrowser/#/R-DRE-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Danio rerio 456216 R-DRE-216723 https://reactome.org/PathwayBrowser/#/R-DRE-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Danio rerio 456216 R-DRE-216757 https://reactome.org/PathwayBrowser/#/R-DRE-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Danio rerio 456216 R-DRE-2168079 https://reactome.org/PathwayBrowser/#/R-DRE-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Danio rerio 456216 R-DRE-2197690 https://reactome.org/PathwayBrowser/#/R-DRE-2197690 Detachment of WASP/WAVE IEA Danio rerio 456216 R-DRE-2245218 https://reactome.org/PathwayBrowser/#/R-DRE-2245218 CDK1 phosphorylates PHF8 IEA Danio rerio 456216 R-DRE-2267372 https://reactome.org/PathwayBrowser/#/R-DRE-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Danio rerio 456216 R-DRE-2294580 https://reactome.org/PathwayBrowser/#/R-DRE-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Danio rerio 456216 R-DRE-2294600 https://reactome.org/PathwayBrowser/#/R-DRE-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Danio rerio 456216 R-DRE-2316434 https://reactome.org/PathwayBrowser/#/R-DRE-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 456216 R-DRE-2422927 https://reactome.org/PathwayBrowser/#/R-DRE-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Danio rerio 456216 R-DRE-2430535 https://reactome.org/PathwayBrowser/#/R-DRE-2430535 MASTL phosphorylates ENSA IEA Danio rerio 456216 R-DRE-2466068 https://reactome.org/PathwayBrowser/#/R-DRE-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Danio rerio 456216 R-DRE-2468293 https://reactome.org/PathwayBrowser/#/R-DRE-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Danio rerio 456216 R-DRE-2562526 https://reactome.org/PathwayBrowser/#/R-DRE-2562526 PLK1 phosphorylates OPTN IEA Danio rerio 456216 R-DRE-2581474 https://reactome.org/PathwayBrowser/#/R-DRE-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Danio rerio 456216 R-DRE-266082 https://reactome.org/PathwayBrowser/#/R-DRE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Danio rerio 456216 R-DRE-3000327 https://reactome.org/PathwayBrowser/#/R-DRE-3000327 PLK1 phosphorylates BORA IEA Danio rerio 456216 R-DRE-3132737 https://reactome.org/PathwayBrowser/#/R-DRE-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Danio rerio 456216 R-DRE-3229102 https://reactome.org/PathwayBrowser/#/R-DRE-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Danio rerio 456216 R-DRE-3238999 https://reactome.org/PathwayBrowser/#/R-DRE-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Danio rerio 456216 R-DRE-3239014 https://reactome.org/PathwayBrowser/#/R-DRE-3239014 MAPKAPK5 phosphorylates TP53 IEA Danio rerio 456216 R-DRE-3239019 https://reactome.org/PathwayBrowser/#/R-DRE-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Danio rerio 456216 R-DRE-3249371 https://reactome.org/PathwayBrowser/#/R-DRE-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Danio rerio 456216 R-DRE-3249379 https://reactome.org/PathwayBrowser/#/R-DRE-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Danio rerio 456216 R-DRE-3249390 https://reactome.org/PathwayBrowser/#/R-DRE-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Danio rerio 456216 R-DRE-3371422 https://reactome.org/PathwayBrowser/#/R-DRE-3371422 ATP hydrolysis by HSP70 IEA Danio rerio 456216 R-DRE-3371503 https://reactome.org/PathwayBrowser/#/R-DRE-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Danio rerio 456216 R-DRE-373747 https://reactome.org/PathwayBrowser/#/R-DRE-373747 Phosphorylation of nephrin by FYN IEA Danio rerio 456216 R-DRE-374701 https://reactome.org/PathwayBrowser/#/R-DRE-374701 Phosphorylation of DCC by Fyn IEA Danio rerio 456216 R-DRE-3769394 https://reactome.org/PathwayBrowser/#/R-DRE-3769394 AKT phosphorylates CBY1 IEA Danio rerio 456216 R-DRE-377186 https://reactome.org/PathwayBrowser/#/R-DRE-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Danio rerio 456216 R-DRE-3772435 https://reactome.org/PathwayBrowser/#/R-DRE-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Danio rerio 456216 R-DRE-377640 https://reactome.org/PathwayBrowser/#/R-DRE-377640 Autophosphorylation of SRC IEA Danio rerio 456216 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 456216 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 456216 R-DRE-380780 https://reactome.org/PathwayBrowser/#/R-DRE-380780 Activation of Src IEA Danio rerio 456216 R-DRE-382560 https://reactome.org/PathwayBrowser/#/R-DRE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Danio rerio 456216 R-DRE-382575 https://reactome.org/PathwayBrowser/#/R-DRE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Danio rerio 456216 R-DRE-383190 https://reactome.org/PathwayBrowser/#/R-DRE-383190 HCO3- transport through ion channel IEA Danio rerio 456216 R-DRE-3857329 https://reactome.org/PathwayBrowser/#/R-DRE-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Danio rerio 456216 R-DRE-389083 https://reactome.org/PathwayBrowser/#/R-DRE-389083 Autophosphorylation of PDGF alpha receptors IEA Danio rerio 456216 R-DRE-389086 https://reactome.org/PathwayBrowser/#/R-DRE-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Danio rerio 456216 R-DRE-392195 https://reactome.org/PathwayBrowser/#/R-DRE-392195 Gi activation by P2Y purinoceptor 12 IEA Danio rerio 456216 R-DRE-3928578 https://reactome.org/PathwayBrowser/#/R-DRE-3928578 EPH receptors autophosphorylate IEA Danio rerio 456216 R-DRE-3928604 https://reactome.org/PathwayBrowser/#/R-DRE-3928604 SFKs phosphorylate VAV2,3 IEA Danio rerio 456216 R-DRE-399939 https://reactome.org/PathwayBrowser/#/R-DRE-399939 Autophosphorylation of PAK IEA Danio rerio 456216 R-DRE-399944 https://reactome.org/PathwayBrowser/#/R-DRE-399944 Phosphorylation of CRMPs by Cdk5 IEA Danio rerio 456216 R-DRE-399952 https://reactome.org/PathwayBrowser/#/R-DRE-399952 Phosphorylation of LIMK-1 by PAK IEA Danio rerio 456216 R-DRE-4085028 https://reactome.org/PathwayBrowser/#/R-DRE-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Danio rerio 456216 R-DRE-4086410 https://reactome.org/PathwayBrowser/#/R-DRE-4086410 CDK1 phosphorylates BORA IEA Danio rerio 456216 R-DRE-4088024 https://reactome.org/PathwayBrowser/#/R-DRE-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Danio rerio 456216 R-DRE-4088134 https://reactome.org/PathwayBrowser/#/R-DRE-4088134 PLK1 phosphorylates FOXM1 IEA Danio rerio 456216 R-DRE-4093332 https://reactome.org/PathwayBrowser/#/R-DRE-4093332 p-EPHB phosphorylates SDC2 IEA Danio rerio 456216 R-DRE-417829 https://reactome.org/PathwayBrowser/#/R-DRE-417829 P2RY12 binds ADP IEA Danio rerio 456216 R-DRE-417843 https://reactome.org/PathwayBrowser/#/R-DRE-417843 P2Y13 binds ADP IEA Danio rerio 456216 R-DRE-417908 https://reactome.org/PathwayBrowser/#/R-DRE-417908 P2RY1 binds ADP IEA Danio rerio 456216 R-DRE-419644 https://reactome.org/PathwayBrowser/#/R-DRE-419644 Transphosphorylation of pLIMK1 IEA Danio rerio 456216 R-DRE-428941 https://reactome.org/PathwayBrowser/#/R-DRE-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Danio rerio 456216 R-DRE-428961 https://reactome.org/PathwayBrowser/#/R-DRE-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Danio rerio 456216 R-DRE-429016 https://reactome.org/PathwayBrowser/#/R-DRE-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Danio rerio 456216 R-DRE-429157 https://reactome.org/PathwayBrowser/#/R-DRE-429157 ABCC4 accumulation of dense granule contents IEA Danio rerio 456216 R-DRE-429698 https://reactome.org/PathwayBrowser/#/R-DRE-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Danio rerio 456216 R-DRE-429714 https://reactome.org/PathwayBrowser/#/R-DRE-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Danio rerio 456216 R-DRE-432148 https://reactome.org/PathwayBrowser/#/R-DRE-432148 Fgr may phosphorylate p38 MAPK IEA Danio rerio 456216 R-DRE-432232 https://reactome.org/PathwayBrowser/#/R-DRE-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Danio rerio 456216 R-DRE-437162 https://reactome.org/PathwayBrowser/#/R-DRE-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Danio rerio 456216 R-DRE-4420117 https://reactome.org/PathwayBrowser/#/R-DRE-4420117 VEGFR2 autophosphorylates IEA Danio rerio 456216 R-DRE-4420121 https://reactome.org/PathwayBrowser/#/R-DRE-4420121 SFKs phosphorylate PLCG1 IEA Danio rerio 456216 R-DRE-4420206 https://reactome.org/PathwayBrowser/#/R-DRE-4420206 Phosphorylation of SRC-1 IEA Danio rerio 456216 R-DRE-447074 https://reactome.org/PathwayBrowser/#/R-DRE-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Danio rerio 456216 R-DRE-448955 https://reactome.org/PathwayBrowser/#/R-DRE-448955 Phosphorylation of MEF2 proteins by p38 IEA Danio rerio 456216 R-DRE-450222 https://reactome.org/PathwayBrowser/#/R-DRE-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Danio rerio 456216 R-DRE-450325 https://reactome.org/PathwayBrowser/#/R-DRE-450325 c-FOS activation by phospho ERK1/2 IEA Danio rerio 456216 R-DRE-450333 https://reactome.org/PathwayBrowser/#/R-DRE-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Danio rerio 456216 R-DRE-450474 https://reactome.org/PathwayBrowser/#/R-DRE-450474 MK2 phosphorylates BRF1 IEA Danio rerio 456216 R-DRE-450490 https://reactome.org/PathwayBrowser/#/R-DRE-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Danio rerio 456216 R-DRE-450499 https://reactome.org/PathwayBrowser/#/R-DRE-450499 Protein Kinase B (AKT) phosphorylates KSRP IEA Danio rerio 456216 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 456216 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 456216 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 456216 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 456216 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 456216 R-DRE-504054 https://reactome.org/PathwayBrowser/#/R-DRE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Danio rerio 456216 R-DRE-5218804 https://reactome.org/PathwayBrowser/#/R-DRE-5218804 p38 MAPK activation by VEGFR IEA Danio rerio 456216 R-DRE-5218805 https://reactome.org/PathwayBrowser/#/R-DRE-5218805 PKC autophosphorylates IEA Danio rerio 456216 R-DRE-5218806 https://reactome.org/PathwayBrowser/#/R-DRE-5218806 FYN autophosphorylates IEA Danio rerio 456216 R-DRE-5218812 https://reactome.org/PathwayBrowser/#/R-DRE-5218812 FYN phosphorylates PAK2 IEA Danio rerio 456216 R-DRE-5218814 https://reactome.org/PathwayBrowser/#/R-DRE-5218814 PAK2 autophorylates IEA Danio rerio 456216 R-DRE-5218819 https://reactome.org/PathwayBrowser/#/R-DRE-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 456216 R-DRE-5218821 https://reactome.org/PathwayBrowser/#/R-DRE-5218821 PDK1 phosphorylates PKC IEA Danio rerio 456216 R-DRE-5218854 https://reactome.org/PathwayBrowser/#/R-DRE-5218854 p-Y420-FYN is phosphorylated on S21 IEA Danio rerio 456216 R-DRE-5218916 https://reactome.org/PathwayBrowser/#/R-DRE-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Danio rerio 456216 R-DRE-5223317 https://reactome.org/PathwayBrowser/#/R-DRE-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Danio rerio 456216 R-DRE-5244669 https://reactome.org/PathwayBrowser/#/R-DRE-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Danio rerio 456216 R-DRE-5251955 https://reactome.org/PathwayBrowser/#/R-DRE-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Danio rerio 456216 R-DRE-5251959 https://reactome.org/PathwayBrowser/#/R-DRE-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Danio rerio 456216 R-DRE-5252079 https://reactome.org/PathwayBrowser/#/R-DRE-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Danio rerio 456216 R-DRE-5357477 https://reactome.org/PathwayBrowser/#/R-DRE-5357477 PAK1-3 phosphorylates VE-cadherin IEA Danio rerio 456216 R-DRE-5358525 https://reactome.org/PathwayBrowser/#/R-DRE-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Danio rerio 456216 R-DRE-5358912 https://reactome.org/PathwayBrowser/#/R-DRE-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Danio rerio 456216 R-DRE-5362459 https://reactome.org/PathwayBrowser/#/R-DRE-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Danio rerio 456216 R-DRE-5444516 https://reactome.org/PathwayBrowser/#/R-DRE-5444516 Formation of MSH2:MSH6 Complex IEA Danio rerio 456216 R-DRE-5610720 https://reactome.org/PathwayBrowser/#/R-DRE-5610720 PKA phosphorylates GLI3 IEA Danio rerio 456216 R-DRE-5610722 https://reactome.org/PathwayBrowser/#/R-DRE-5610722 CK1 phosphorylates p-GLI3 IEA Danio rerio 456216 R-DRE-5617179 https://reactome.org/PathwayBrowser/#/R-DRE-5617179 PRKACA phosphorylates TNNI3 IEA Danio rerio 456216 R-DRE-5618107 https://reactome.org/PathwayBrowser/#/R-DRE-5618107 ATP binding to HSP90 triggers conformation change IEA Danio rerio 456216 R-DRE-5621355 https://reactome.org/PathwayBrowser/#/R-DRE-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Danio rerio 456216 R-DRE-5623667 https://reactome.org/PathwayBrowser/#/R-DRE-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Danio rerio 456216 R-DRE-5625784 https://reactome.org/PathwayBrowser/#/R-DRE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Danio rerio 456216 R-DRE-5627775 https://reactome.org/PathwayBrowser/#/R-DRE-5627775 Autophosphorylation of PAK1,2,3 IEA Danio rerio 456216 R-DRE-5635842 https://reactome.org/PathwayBrowser/#/R-DRE-5635842 ULK3 phosphorylates GLI IEA Danio rerio 456216 R-DRE-5654147 https://reactome.org/PathwayBrowser/#/R-DRE-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Danio rerio 456216 R-DRE-5654149 https://reactome.org/PathwayBrowser/#/R-DRE-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Danio rerio 456216 R-DRE-5654151 https://reactome.org/PathwayBrowser/#/R-DRE-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Danio rerio 456216 R-DRE-5654222 https://reactome.org/PathwayBrowser/#/R-DRE-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Danio rerio 456216 R-DRE-5654560 https://reactome.org/PathwayBrowser/#/R-DRE-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Danio rerio 456216 R-DRE-5654575 https://reactome.org/PathwayBrowser/#/R-DRE-5654575 Activated FGFR1 phosphorylates FRS2 IEA Danio rerio 456216 R-DRE-5654578 https://reactome.org/PathwayBrowser/#/R-DRE-5654578 Activated FGFR1 phosphorylates FRS3 IEA Danio rerio 456216 R-DRE-5654582 https://reactome.org/PathwayBrowser/#/R-DRE-5654582 Activated FGFR1 phosphorylates SHC1 IEA Danio rerio 456216 R-DRE-5654587 https://reactome.org/PathwayBrowser/#/R-DRE-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Danio rerio 456216 R-DRE-5654605 https://reactome.org/PathwayBrowser/#/R-DRE-5654605 Activated FGFR2 phosphorylates FRS3 IEA Danio rerio 456216 R-DRE-5654607 https://reactome.org/PathwayBrowser/#/R-DRE-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Danio rerio 456216 R-DRE-5654628 https://reactome.org/PathwayBrowser/#/R-DRE-5654628 Activated FGFR3 phosphorylates FRS3 IEA Danio rerio 456216 R-DRE-5654631 https://reactome.org/PathwayBrowser/#/R-DRE-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Danio rerio 456216 R-DRE-5654653 https://reactome.org/PathwayBrowser/#/R-DRE-5654653 Activated FGFR4 phosphorylates FRS3 IEA Danio rerio 456216 R-DRE-5654690 https://reactome.org/PathwayBrowser/#/R-DRE-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 456216 R-DRE-5654989 https://reactome.org/PathwayBrowser/#/R-DRE-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Danio rerio 456216 R-DRE-5662466 https://reactome.org/PathwayBrowser/#/R-DRE-5662466 XYLB phosphorylates D-xylulose IEA Danio rerio 456216 R-DRE-5671763 https://reactome.org/PathwayBrowser/#/R-DRE-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Danio rerio 456216 R-DRE-5672010 https://reactome.org/PathwayBrowser/#/R-DRE-5672010 Active MTORC1 phosphorylates ULK1 IEA Danio rerio 456216 R-DRE-5672027 https://reactome.org/PathwayBrowser/#/R-DRE-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Danio rerio 456216 R-DRE-5672828 https://reactome.org/PathwayBrowser/#/R-DRE-5672828 mTORC1 phosphorylates AKT1S1 IEA Danio rerio 456216 R-DRE-5673768 https://reactome.org/PathwayBrowser/#/R-DRE-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Danio rerio 456216 R-DRE-5674130 https://reactome.org/PathwayBrowser/#/R-DRE-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Danio rerio 456216 R-DRE-5674373 https://reactome.org/PathwayBrowser/#/R-DRE-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Danio rerio 456216 R-DRE-5674496 https://reactome.org/PathwayBrowser/#/R-DRE-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Danio rerio 456216 R-DRE-5678863 https://reactome.org/PathwayBrowser/#/R-DRE-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Danio rerio 456216 R-DRE-5679041 https://reactome.org/PathwayBrowser/#/R-DRE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Danio rerio 456216 R-DRE-5682101 https://reactome.org/PathwayBrowser/#/R-DRE-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Danio rerio 456216 R-DRE-5687086 https://reactome.org/PathwayBrowser/#/R-DRE-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Danio rerio 456216 R-DRE-5687088 https://reactome.org/PathwayBrowser/#/R-DRE-5687088 PKA phosphorylates MAPKAPK5 IEA Danio rerio 456216 R-DRE-5687094 https://reactome.org/PathwayBrowser/#/R-DRE-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Danio rerio 456216 R-DRE-5687101 https://reactome.org/PathwayBrowser/#/R-DRE-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Danio rerio 456216 R-DRE-5687121 https://reactome.org/PathwayBrowser/#/R-DRE-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Danio rerio 456216 R-DRE-5690250 https://reactome.org/PathwayBrowser/#/R-DRE-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Danio rerio 456216 R-DRE-5690996 https://reactome.org/PathwayBrowser/#/R-DRE-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Danio rerio 456216 R-DRE-5692480 https://reactome.org/PathwayBrowser/#/R-DRE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Danio rerio 456216 R-DRE-5692755 https://reactome.org/PathwayBrowser/#/R-DRE-5692755 CDK1 phosphorylates MAPK6 IEA Danio rerio 456216 R-DRE-5692775 https://reactome.org/PathwayBrowser/#/R-DRE-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Danio rerio 456216 R-DRE-5692779 https://reactome.org/PathwayBrowser/#/R-DRE-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Danio rerio 456216 R-DRE-5696021 https://reactome.org/PathwayBrowser/#/R-DRE-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Danio rerio 456216 R-DRE-5696074 https://reactome.org/PathwayBrowser/#/R-DRE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Danio rerio 456216 R-DRE-5696839 https://reactome.org/PathwayBrowser/#/R-DRE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Danio rerio 456216 R-DRE-6782131 https://reactome.org/PathwayBrowser/#/R-DRE-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Danio rerio 456216 R-DRE-6784319 https://reactome.org/PathwayBrowser/#/R-DRE-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Danio rerio 456216 R-DRE-6784324 https://reactome.org/PathwayBrowser/#/R-DRE-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Danio rerio 456216 R-DRE-6788798 https://reactome.org/PathwayBrowser/#/R-DRE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 456216 R-DRE-6788810 https://reactome.org/PathwayBrowser/#/R-DRE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 456216 R-DRE-6788855 https://reactome.org/PathwayBrowser/#/R-DRE-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Danio rerio 456216 R-DRE-6788867 https://reactome.org/PathwayBrowser/#/R-DRE-6788867 FN3K phosphorylates ketosamines IEA Danio rerio 456216 R-DRE-6793661 https://reactome.org/PathwayBrowser/#/R-DRE-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Danio rerio 456216 R-DRE-6795460 https://reactome.org/PathwayBrowser/#/R-DRE-6795460 SGK1 phosphorylates MDM2 IEA Danio rerio 456216 R-DRE-6795473 https://reactome.org/PathwayBrowser/#/R-DRE-6795473 PDPK1 phosphorylates SGK1 IEA Danio rerio 456216 R-DRE-6797606 https://reactome.org/PathwayBrowser/#/R-DRE-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Danio rerio 456216 R-DRE-6799495 https://reactome.org/PathwayBrowser/#/R-DRE-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Danio rerio 456216 R-DRE-6801342 https://reactome.org/PathwayBrowser/#/R-DRE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio 456216 R-DRE-6801456 https://reactome.org/PathwayBrowser/#/R-DRE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Danio rerio 456216 R-DRE-6801666 https://reactome.org/PathwayBrowser/#/R-DRE-6801666 PLK2 phosphorylates CENPJ IEA Danio rerio 456216 R-DRE-6803545 https://reactome.org/PathwayBrowser/#/R-DRE-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Danio rerio 456216 R-DRE-6805103 https://reactome.org/PathwayBrowser/#/R-DRE-6805103 AURKA phosphorylates TP53 IEA Danio rerio 456216 R-DRE-6805109 https://reactome.org/PathwayBrowser/#/R-DRE-6805109 CDK2 phosphorylates TP53 IEA Danio rerio 456216 R-DRE-6805276 https://reactome.org/PathwayBrowser/#/R-DRE-6805276 CDK5 phosphorylates TP53 IEA Danio rerio 456216 R-DRE-6805285 https://reactome.org/PathwayBrowser/#/R-DRE-6805285 PLK3 phosphorylates TP53 IEA Danio rerio 456216 R-DRE-6805470 https://reactome.org/PathwayBrowser/#/R-DRE-6805470 AMPK phosphorylates TP53 IEA Danio rerio 456216 R-DRE-6805640 https://reactome.org/PathwayBrowser/#/R-DRE-6805640 AKT phosphorylates KAT6A IEA Danio rerio 456216 R-DRE-6806877 https://reactome.org/PathwayBrowser/#/R-DRE-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Danio rerio 456216 R-DRE-6806967 https://reactome.org/PathwayBrowser/#/R-DRE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Danio rerio 456216 R-DRE-6807868 https://reactome.org/PathwayBrowser/#/R-DRE-6807868 GBF1 stimulates ARF nucleotide exchange IEA Danio rerio 456216 R-DRE-6810233 https://reactome.org/PathwayBrowser/#/R-DRE-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Danio rerio 456216 R-DRE-6811454 https://reactome.org/PathwayBrowser/#/R-DRE-6811454 MAPKs phosphorylate PP2A IEA Danio rerio 456216 R-DRE-6811522 https://reactome.org/PathwayBrowser/#/R-DRE-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Danio rerio 456216 R-DRE-6814119 https://reactome.org/PathwayBrowser/#/R-DRE-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Danio rerio 456216 R-DRE-6814120 https://reactome.org/PathwayBrowser/#/R-DRE-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Danio rerio 456216 R-DRE-6814124 https://reactome.org/PathwayBrowser/#/R-DRE-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Danio rerio 456216 R-DRE-69005 https://reactome.org/PathwayBrowser/#/R-DRE-69005 Cdc6 protein is phosphorylated by CDK IEA Danio rerio 456216 R-DRE-69195 https://reactome.org/PathwayBrowser/#/R-DRE-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Danio rerio 456216 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 456216 R-DRE-70349 https://reactome.org/PathwayBrowser/#/R-DRE-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Danio rerio 456216 R-DRE-70355 https://reactome.org/PathwayBrowser/#/R-DRE-70355 GALK1 phosphorylates Gal to Gal1P IEA Danio rerio 456216 R-DRE-70420 https://reactome.org/PathwayBrowser/#/R-DRE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Danio rerio 456216 R-DRE-70467 https://reactome.org/PathwayBrowser/#/R-DRE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Danio rerio 456216 R-DRE-70486 https://reactome.org/PathwayBrowser/#/R-DRE-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Danio rerio 456216 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 456216 R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Danio rerio 456216 R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Danio rerio 456216 R-DRE-70606 https://reactome.org/PathwayBrowser/#/R-DRE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Danio rerio 456216 R-DRE-70997 https://reactome.org/PathwayBrowser/#/R-DRE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Danio rerio 456216 R-DRE-71031 https://reactome.org/PathwayBrowser/#/R-DRE-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Danio rerio 456216 R-DRE-71401 https://reactome.org/PathwayBrowser/#/R-DRE-71401 OGDH dimer decarboxylates 2-OG IEA Danio rerio 456216 R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 456216 R-DRE-71802 https://reactome.org/PathwayBrowser/#/R-DRE-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Danio rerio 456216 R-DRE-71850 https://reactome.org/PathwayBrowser/#/R-DRE-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Danio rerio 456216 R-DRE-72621 https://reactome.org/PathwayBrowser/#/R-DRE-72621 Ribosomal scanning IEA Danio rerio 456216 R-DRE-73548 https://reactome.org/PathwayBrowser/#/R-DRE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Danio rerio 456216 R-DRE-73598 https://reactome.org/PathwayBrowser/#/R-DRE-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Danio rerio 456216 R-DRE-73599 https://reactome.org/PathwayBrowser/#/R-DRE-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Danio rerio 456216 R-DRE-73632 https://reactome.org/PathwayBrowser/#/R-DRE-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Danio rerio 456216 R-DRE-73635 https://reactome.org/PathwayBrowser/#/R-DRE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Danio rerio 456216 R-DRE-73647 https://reactome.org/PathwayBrowser/#/R-DRE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Danio rerio 456216 R-DRE-73722 https://reactome.org/PathwayBrowser/#/R-DRE-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Danio rerio 456216 R-DRE-73788 https://reactome.org/PathwayBrowser/#/R-DRE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Danio rerio 456216 R-DRE-73805 https://reactome.org/PathwayBrowser/#/R-DRE-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Danio rerio 456216 R-DRE-73810 https://reactome.org/PathwayBrowser/#/R-DRE-73810 FGAM + ATP => AIR + ADP + Pi IEA Danio rerio 456216 R-DRE-73814 https://reactome.org/PathwayBrowser/#/R-DRE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Danio rerio 456216 R-DRE-74207 https://reactome.org/PathwayBrowser/#/R-DRE-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Danio rerio 456216 R-DRE-74715 https://reactome.org/PathwayBrowser/#/R-DRE-74715 Autophosphorylation of insulin receptor IEA Danio rerio 456216 R-DRE-75125 https://reactome.org/PathwayBrowser/#/R-DRE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Danio rerio 456216 R-DRE-75126 https://reactome.org/PathwayBrowser/#/R-DRE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Danio rerio 456216 R-DRE-75848 https://reactome.org/PathwayBrowser/#/R-DRE-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Danio rerio 456216 R-DRE-77071 https://reactome.org/PathwayBrowser/#/R-DRE-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Danio rerio 456216 R-DRE-873918 https://reactome.org/PathwayBrowser/#/R-DRE-873918 Transphosphorylation of JAK1 IEA Danio rerio 456216 R-DRE-873919 https://reactome.org/PathwayBrowser/#/R-DRE-873919 Phosphorylation of JAK2 IEA Danio rerio 456216 R-DRE-873922 https://reactome.org/PathwayBrowser/#/R-DRE-873922 Phosphorylation of STAT1 by JAK kinases IEA Danio rerio 456216 R-DRE-873924 https://reactome.org/PathwayBrowser/#/R-DRE-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Danio rerio 456216 R-DRE-8848005 https://reactome.org/PathwayBrowser/#/R-DRE-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Danio rerio 456216 R-DRE-8848077 https://reactome.org/PathwayBrowser/#/R-DRE-8848077 PTK6 phosphorylates STAP2 IEA Danio rerio 456216 R-DRE-8848436 https://reactome.org/PathwayBrowser/#/R-DRE-8848436 PTK6 phosphorylates CDKN1B IEA Danio rerio 456216 R-DRE-8848606 https://reactome.org/PathwayBrowser/#/R-DRE-8848606 PTK6 phosphorylates PXN IEA Danio rerio 456216 R-DRE-8848758 https://reactome.org/PathwayBrowser/#/R-DRE-8848758 PTK6 phosphorylates AKT1 IEA Danio rerio 456216 R-DRE-8848776 https://reactome.org/PathwayBrowser/#/R-DRE-8848776 PTK6 phosphorylates DOK1 IEA Danio rerio 456216 R-DRE-8848818 https://reactome.org/PathwayBrowser/#/R-DRE-8848818 PTK6 phosphorylates CBL IEA Danio rerio 456216 R-DRE-8848975 https://reactome.org/PathwayBrowser/#/R-DRE-8848975 PTK6 phosphorylates KHDRBS1 IEA Danio rerio 456216 R-DRE-8849032 https://reactome.org/PathwayBrowser/#/R-DRE-8849032 PTK6 phosphorylates KHDRBS2 IEA Danio rerio 456216 R-DRE-8849068 https://reactome.org/PathwayBrowser/#/R-DRE-8849068 PTK6 phosphorylates ARHGAP35 IEA Danio rerio 456216 R-DRE-8849463 https://reactome.org/PathwayBrowser/#/R-DRE-8849463 PTK6 phosphorylates SFPQ IEA Danio rerio 456216 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 456216 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 456216 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 456216 R-DRE-8852317 https://reactome.org/PathwayBrowser/#/R-DRE-8852317 PLK1 phosphorylates GTSE1 IEA Danio rerio 456216 R-DRE-8852552 https://reactome.org/PathwayBrowser/#/R-DRE-8852552 MST1R autophosphorylates IEA Danio rerio 456216 R-DRE-8853444 https://reactome.org/PathwayBrowser/#/R-DRE-8853444 AURKA phosphorylates PHLDA1 IEA Danio rerio 456216 R-DRE-8869607 https://reactome.org/PathwayBrowser/#/R-DRE-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Danio rerio 456216 R-DRE-8869627 https://reactome.org/PathwayBrowser/#/R-DRE-8869627 NMRK2 phosphorylates NR to yield NMN IEA Danio rerio 456216 R-DRE-8875451 https://reactome.org/PathwayBrowser/#/R-DRE-8875451 MET phosphorylates CBL IEA Danio rerio 456216 R-DRE-8931653 https://reactome.org/PathwayBrowser/#/R-DRE-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Danio rerio 456216 R-DRE-8937807 https://reactome.org/PathwayBrowser/#/R-DRE-8937807 SRC phosphorylates RUNX3 IEA Danio rerio 456216 R-DRE-8942575 https://reactome.org/PathwayBrowser/#/R-DRE-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Danio rerio 456216 R-DRE-8942607 https://reactome.org/PathwayBrowser/#/R-DRE-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Danio rerio 456216 R-DRE-8944454 https://reactome.org/PathwayBrowser/#/R-DRE-8944454 mTORC1 phosphorylates MAF1 IEA Danio rerio 456216 R-DRE-8948143 https://reactome.org/PathwayBrowser/#/R-DRE-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Danio rerio 456216 R-DRE-8948757 https://reactome.org/PathwayBrowser/#/R-DRE-8948757 AKT phosphorylates MKRN1 IEA Danio rerio 456216 R-DRE-8955844 https://reactome.org/PathwayBrowser/#/R-DRE-8955844 RBKS phosphorylates ribose to R5P IEA Danio rerio 456216 R-DRE-8964242 https://reactome.org/PathwayBrowser/#/R-DRE-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Danio rerio 456216 R-DRE-8986994 https://reactome.org/PathwayBrowser/#/R-DRE-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Danio rerio 456216 R-DRE-8987012 https://reactome.org/PathwayBrowser/#/R-DRE-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Danio rerio 456216 R-DRE-8987084 https://reactome.org/PathwayBrowser/#/R-DRE-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Danio rerio 456216 R-DRE-8987129 https://reactome.org/PathwayBrowser/#/R-DRE-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Danio rerio 456216 R-DRE-8987150 https://reactome.org/PathwayBrowser/#/R-DRE-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Danio rerio 456216 R-DRE-8987179 https://reactome.org/PathwayBrowser/#/R-DRE-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Danio rerio 456216 R-DRE-8987255 https://reactome.org/PathwayBrowser/#/R-DRE-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Danio rerio 456216 R-DRE-9006850 https://reactome.org/PathwayBrowser/#/R-DRE-9006850 IL21 receptor JAK phosphorylation IEA Danio rerio 456216 R-DRE-9006870 https://reactome.org/PathwayBrowser/#/R-DRE-9006870 IL21 receptor STAT phosphorylation IEA Danio rerio 456216 R-DRE-9008043 https://reactome.org/PathwayBrowser/#/R-DRE-9008043 MAPK8 phosphorylation IEA Danio rerio 456216 R-DRE-9008684 https://reactome.org/PathwayBrowser/#/R-DRE-9008684 TBK1 phosphorylation IEA Danio rerio 456216 R-DRE-9021609 https://reactome.org/PathwayBrowser/#/R-DRE-9021609 ESR-associated SRC autophosphorylates IEA Danio rerio 456216 R-DRE-909552 https://reactome.org/PathwayBrowser/#/R-DRE-909552 Phosphorylation of STAT1 at Ser727 IEA Danio rerio 456216 R-DRE-913996 https://reactome.org/PathwayBrowser/#/R-DRE-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Danio rerio 456216 R-DRE-917841 https://reactome.org/PathwayBrowser/#/R-DRE-917841 Acidification of Tf:TfR1 containing endosome IEA Danio rerio 456216 R-DRE-927889 https://reactome.org/PathwayBrowser/#/R-DRE-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Danio rerio 456216 R-DRE-936802 https://reactome.org/PathwayBrowser/#/R-DRE-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Danio rerio 456216 R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 456216 R-DRE-939763 https://reactome.org/PathwayBrowser/#/R-DRE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Danio rerio 456216 R-DRE-947591 https://reactome.org/PathwayBrowser/#/R-DRE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Danio rerio 456216 R-DRE-9606884 https://reactome.org/PathwayBrowser/#/R-DRE-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Danio rerio 456216 R-DRE-9610153 https://reactome.org/PathwayBrowser/#/R-DRE-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Danio rerio 456216 R-DRE-9610156 https://reactome.org/PathwayBrowser/#/R-DRE-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Danio rerio 456216 R-DRE-9612501 https://reactome.org/PathwayBrowser/#/R-DRE-9612501 SGK phosphorylates CREB1 IEA Danio rerio 456216 R-DRE-9624526 https://reactome.org/PathwayBrowser/#/R-DRE-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Danio rerio 456216 R-DRE-9624800 https://reactome.org/PathwayBrowser/#/R-DRE-9624800 CDK1 phosphorylates LBR IEA Danio rerio 456216 R-DRE-9626817 https://reactome.org/PathwayBrowser/#/R-DRE-9626817 PKC phosphorylates NCF1 IEA Danio rerio 456216 R-DRE-9627089 https://reactome.org/PathwayBrowser/#/R-DRE-9627089 CASP9 is phosphorylated at T412 IEA Danio rerio 456216 R-DRE-9632868 https://reactome.org/PathwayBrowser/#/R-DRE-9632868 CDKN1B is phosphorylated in response to estrogen IEA Danio rerio 456216 R-DRE-964958 https://reactome.org/PathwayBrowser/#/R-DRE-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Danio rerio 456216 R-DRE-964962 https://reactome.org/PathwayBrowser/#/R-DRE-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Danio rerio 456216 R-DRE-964970 https://reactome.org/PathwayBrowser/#/R-DRE-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Danio rerio 456216 R-DRE-9684118 https://reactome.org/PathwayBrowser/#/R-DRE-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Danio rerio 456216 R-DRE-9699579 https://reactome.org/PathwayBrowser/#/R-DRE-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Danio rerio 456216 R-DRE-9700171 https://reactome.org/PathwayBrowser/#/R-DRE-9700171 Active ALK phosphorylates PLCG1 IEA Danio rerio 456216 R-DRE-9731111 https://reactome.org/PathwayBrowser/#/R-DRE-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Danio rerio 456216 R-DRE-9734547 https://reactome.org/PathwayBrowser/#/R-DRE-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Danio rerio 456216 R-DRE-9748949 https://reactome.org/PathwayBrowser/#/R-DRE-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Danio rerio 456216 R-DRE-9748963 https://reactome.org/PathwayBrowser/#/R-DRE-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Danio rerio 456216 R-DRE-9748969 https://reactome.org/PathwayBrowser/#/R-DRE-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Danio rerio 456216 R-DRE-9748999 https://reactome.org/PathwayBrowser/#/R-DRE-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Danio rerio 456216 R-DRE-9750546 https://reactome.org/PathwayBrowser/#/R-DRE-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 456216 R-DRE-9750617 https://reactome.org/PathwayBrowser/#/R-DRE-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 456216 R-DRE-9750656 https://reactome.org/PathwayBrowser/#/R-DRE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Danio rerio 456216 R-DRE-9753278 https://reactome.org/PathwayBrowser/#/R-DRE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 456216 R-DRE-9753283 https://reactome.org/PathwayBrowser/#/R-DRE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 456216 R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 456216 R-DRE-9754974 https://reactome.org/PathwayBrowser/#/R-DRE-9754974 ADK phosphorylates RBV IEA Danio rerio 456216 R-DRE-9755013 https://reactome.org/PathwayBrowser/#/R-DRE-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Danio rerio 456216 R-DRE-9796053 https://reactome.org/PathwayBrowser/#/R-DRE-9796053 PRKCI phosphorylates NFE2L2 IEA Danio rerio 456216 R-DRE-9824977 https://reactome.org/PathwayBrowser/#/R-DRE-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Danio rerio 456216 R-DRE-982807 https://reactome.org/PathwayBrowser/#/R-DRE-982807 JAK2 phosphorylation of GHR IEA Danio rerio 456216 R-DRE-982810 https://reactome.org/PathwayBrowser/#/R-DRE-982810 JAK2 phosphorylation IEA Danio rerio 456216 R-DRE-9836184 https://reactome.org/PathwayBrowser/#/R-DRE-9836184 p-PKR dimer phosphorylates CDK1 IEA Danio rerio 456216 R-DRE-9836322 https://reactome.org/PathwayBrowser/#/R-DRE-9836322 p-PKR dimer phosphorylates MKK6 IEA Danio rerio 456216 R-DRE-9836362 https://reactome.org/PathwayBrowser/#/R-DRE-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Danio rerio 456216 R-DRE-9836383 https://reactome.org/PathwayBrowser/#/R-DRE-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Danio rerio 456216 R-DRE-9836515 https://reactome.org/PathwayBrowser/#/R-DRE-9836515 p-PKR dimer phosphorylates PTPN2 IEA Danio rerio 456216 R-DRE-9837333 https://reactome.org/PathwayBrowser/#/R-DRE-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Danio rerio 456216 R-DRE-9837337 https://reactome.org/PathwayBrowser/#/R-DRE-9837337 DCAKD phosphorylates DP-CoA IEA Danio rerio 456216 R-DRE-9838321 https://reactome.org/PathwayBrowser/#/R-DRE-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Danio rerio 456216 R-DRE-9839105 https://reactome.org/PathwayBrowser/#/R-DRE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Danio rerio 456216 R-DRE-9839113 https://reactome.org/PathwayBrowser/#/R-DRE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Danio rerio 456216 R-DRE-9842648 https://reactome.org/PathwayBrowser/#/R-DRE-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 IEA Danio rerio 456216 R-DRE-9851972 https://reactome.org/PathwayBrowser/#/R-DRE-9851972 PLK1 phosphorylates FIRRM at S43 IEA Danio rerio 456216 R-DRE-9853369 https://reactome.org/PathwayBrowser/#/R-DRE-9853369 PLK1 phosphorylates FIRMM at S744 IEA Danio rerio 456216 R-DRE-994137 https://reactome.org/PathwayBrowser/#/R-DRE-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Danio rerio 456216 R-DRE-994140 https://reactome.org/PathwayBrowser/#/R-DRE-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Danio rerio 456216 R-GGA-1008248 https://reactome.org/PathwayBrowser/#/R-GGA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Gallus gallus 456216 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 456216 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 456216 R-GGA-109415 https://reactome.org/PathwayBrowser/#/R-GGA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Gallus gallus 456216 R-GGA-109624 https://reactome.org/PathwayBrowser/#/R-GGA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Gallus gallus 456216 R-GGA-109671 https://reactome.org/PathwayBrowser/#/R-GGA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Gallus gallus 456216 R-GGA-109699 https://reactome.org/PathwayBrowser/#/R-GGA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-109759 https://reactome.org/PathwayBrowser/#/R-GGA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Gallus gallus 456216 R-GGA-109903 https://reactome.org/PathwayBrowser/#/R-GGA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Gallus gallus 456216 R-GGA-110133 https://reactome.org/PathwayBrowser/#/R-GGA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Gallus gallus 456216 R-GGA-110137 https://reactome.org/PathwayBrowser/#/R-GGA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Gallus gallus 456216 R-GGA-110138 https://reactome.org/PathwayBrowser/#/R-GGA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 456216 R-GGA-110141 https://reactome.org/PathwayBrowser/#/R-GGA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Gallus gallus 456216 R-GGA-110144 https://reactome.org/PathwayBrowser/#/R-GGA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Gallus gallus 456216 R-GGA-110145 https://reactome.org/PathwayBrowser/#/R-GGA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Gallus gallus 456216 R-GGA-1112510 https://reactome.org/PathwayBrowser/#/R-GGA-1112510 IL6ST is tyrosine phosphorylated IEA Gallus gallus 456216 R-GGA-1112514 https://reactome.org/PathwayBrowser/#/R-GGA-1112514 JAK activation IEA Gallus gallus 456216 R-GGA-1112602 https://reactome.org/PathwayBrowser/#/R-GGA-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Gallus gallus 456216 R-GGA-1112703 https://reactome.org/PathwayBrowser/#/R-GGA-1112703 PTPN11 is phosphorylated IEA Gallus gallus 456216 R-GGA-1112727 https://reactome.org/PathwayBrowser/#/R-GGA-1112727 Serine phosphorylation of STATs IEA Gallus gallus 456216 R-GGA-111898 https://reactome.org/PathwayBrowser/#/R-GGA-111898 Phosphorylation of cPLA2 by ERK-2 IEA Gallus gallus 456216 R-GGA-111915 https://reactome.org/PathwayBrowser/#/R-GGA-111915 CAMK4 autophosphorylates IEA Gallus gallus 456216 R-GGA-111970 https://reactome.org/PathwayBrowser/#/R-GGA-111970 PKC phosphorylates GRK2 IEA Gallus gallus 456216 R-GGA-112342 https://reactome.org/PathwayBrowser/#/R-GGA-112342 Inactivation of MAP2K1 by CDK1 IEA Gallus gallus 456216 R-GGA-112381 https://reactome.org/PathwayBrowser/#/R-GGA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Gallus gallus 456216 R-GGA-114252 https://reactome.org/PathwayBrowser/#/R-GGA-114252 Cleavage of Procaspase-3 by the apoptosome IEA Gallus gallus 456216 R-GGA-114254 https://reactome.org/PathwayBrowser/#/R-GGA-114254 CYCS binds to APAF1 IEA Gallus gallus 456216 R-GGA-114259 https://reactome.org/PathwayBrowser/#/R-GGA-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Gallus gallus 456216 R-GGA-114261 https://reactome.org/PathwayBrowser/#/R-GGA-114261 Cleavage of Procaspase-7 by the apoptosome IEA Gallus gallus 456216 R-GGA-114683 https://reactome.org/PathwayBrowser/#/R-GGA-114683 Phosphorylation of Platelet Sec-1 IEA Gallus gallus 456216 R-GGA-1168459 https://reactome.org/PathwayBrowser/#/R-GGA-1168459 Lyn activates ERK IEA Gallus gallus 456216 R-GGA-1168635 https://reactome.org/PathwayBrowser/#/R-GGA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Gallus gallus 456216 R-GGA-1181149 https://reactome.org/PathwayBrowser/#/R-GGA-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Gallus gallus 456216 R-GGA-1226094 https://reactome.org/PathwayBrowser/#/R-GGA-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Gallus gallus 456216 R-GGA-1226095 https://reactome.org/PathwayBrowser/#/R-GGA-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Gallus gallus 456216 R-GGA-1227783 https://reactome.org/PathwayBrowser/#/R-GGA-1227783 Phosphorylation of IKKs complex mediated by MEKK1 IEA Gallus gallus 456216 R-GGA-1227881 https://reactome.org/PathwayBrowser/#/R-GGA-1227881 Phosphorylation and release of IRF3 IEA Gallus gallus 456216 R-GGA-1227885 https://reactome.org/PathwayBrowser/#/R-GGA-1227885 TBK1/IKK epsilon bind to TANK:TRAF3/TRAF6 complex followed by their activation IEA Gallus gallus 456216 R-GGA-1250195 https://reactome.org/PathwayBrowser/#/R-GGA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Gallus gallus 456216 R-GGA-1250315 https://reactome.org/PathwayBrowser/#/R-GGA-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Gallus gallus 456216 R-GGA-1250348 https://reactome.org/PathwayBrowser/#/R-GGA-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Gallus gallus 456216 R-GGA-1250370 https://reactome.org/PathwayBrowser/#/R-GGA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Gallus gallus 456216 R-GGA-1250462 https://reactome.org/PathwayBrowser/#/R-GGA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Gallus gallus 456216 R-GGA-1295540 https://reactome.org/PathwayBrowser/#/R-GGA-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Gallus gallus 456216 R-GGA-1306957 https://reactome.org/PathwayBrowser/#/R-GGA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus 456216 R-GGA-1306979 https://reactome.org/PathwayBrowser/#/R-GGA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Gallus gallus 456216 R-GGA-1307963 https://reactome.org/PathwayBrowser/#/R-GGA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Gallus gallus 456216 R-GGA-1358791 https://reactome.org/PathwayBrowser/#/R-GGA-1358791 Phosphorylation of USP8 by P-AKT IEA Gallus gallus 456216 R-GGA-1362270 https://reactome.org/PathwayBrowser/#/R-GGA-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Gallus gallus 456216 R-GGA-1369028 https://reactome.org/PathwayBrowser/#/R-GGA-1369028 ABCAs mediate lipid efflux IEA Gallus gallus 456216 R-GGA-1369052 https://reactome.org/PathwayBrowser/#/R-GGA-1369052 ABCAs mediate lipid influx IEA Gallus gallus 456216 R-GGA-1369065 https://reactome.org/PathwayBrowser/#/R-GGA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Gallus gallus 456216 R-GGA-1370505 https://reactome.org/PathwayBrowser/#/R-GGA-1370505 PRLR is phosphorylated at Ser-349 IEA Gallus gallus 456216 R-GGA-139908 https://reactome.org/PathwayBrowser/#/R-GGA-139908 Phosphorylation of DLC2 by MAPK8 IEA Gallus gallus 456216 R-GGA-139918 https://reactome.org/PathwayBrowser/#/R-GGA-139918 Phosphorylation of BIM by JNK IEA Gallus gallus 456216 R-GGA-1433418 https://reactome.org/PathwayBrowser/#/R-GGA-1433418 Phosphorylation of JAK2 IEA Gallus gallus 456216 R-GGA-1433454 https://reactome.org/PathwayBrowser/#/R-GGA-1433454 Phosphorylation of GAB2 by SFKs IEA Gallus gallus 456216 R-GGA-1433488 https://reactome.org/PathwayBrowser/#/R-GGA-1433488 Phosphorylation of SHP2 by SFKs IEA Gallus gallus 456216 R-GGA-1433506 https://reactome.org/PathwayBrowser/#/R-GGA-1433506 Phosphorylation of APS IEA Gallus gallus 456216 R-GGA-1433508 https://reactome.org/PathwayBrowser/#/R-GGA-1433508 PKC alpha interacts with and phosphorylates KIT IEA Gallus gallus 456216 R-GGA-1433514 https://reactome.org/PathwayBrowser/#/R-GGA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Gallus gallus 456216 R-GGA-1454916 https://reactome.org/PathwayBrowser/#/R-GGA-1454916 The ABCC family mediates organic anion transport IEA Gallus gallus 456216 R-GGA-1454928 https://reactome.org/PathwayBrowser/#/R-GGA-1454928 ABCG4 may mediate cholesterol efflux IEA Gallus gallus 456216 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 456216 R-GGA-1467466 https://reactome.org/PathwayBrowser/#/R-GGA-1467466 ABCA4 mediates atRAL transport IEA Gallus gallus 456216 R-GGA-1470009 https://reactome.org/PathwayBrowser/#/R-GGA-1470009 Phosphorylation of STATs IEA Gallus gallus 456216 R-GGA-1472121 https://reactome.org/PathwayBrowser/#/R-GGA-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Gallus gallus 456216 R-GGA-1475422 https://reactome.org/PathwayBrowser/#/R-GGA-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Gallus gallus 456216 R-GGA-1483004 https://reactome.org/PathwayBrowser/#/R-GGA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Gallus gallus 456216 R-GGA-1483222 https://reactome.org/PathwayBrowser/#/R-GGA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Gallus gallus 456216 R-GGA-1497853 https://reactome.org/PathwayBrowser/#/R-GGA-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Gallus gallus 456216 R-GGA-1524186 https://reactome.org/PathwayBrowser/#/R-GGA-1524186 Phosphorylation of PLCgamma by PDGFR IEA Gallus gallus 456216 R-GGA-1549526 https://reactome.org/PathwayBrowser/#/R-GGA-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Gallus gallus 456216 R-GGA-156673 https://reactome.org/PathwayBrowser/#/R-GGA-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Gallus gallus 456216 R-GGA-156682 https://reactome.org/PathwayBrowser/#/R-GGA-156682 PLK1 phosphorylates NUDC IEA Gallus gallus 456216 R-GGA-156699 https://reactome.org/PathwayBrowser/#/R-GGA-156699 Inactivation of Wee1 kinase IEA Gallus gallus 456216 R-GGA-163010 https://reactome.org/PathwayBrowser/#/R-GGA-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Gallus gallus 456216 R-GGA-163215 https://reactome.org/PathwayBrowser/#/R-GGA-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Gallus gallus 456216 R-GGA-1632857 https://reactome.org/PathwayBrowser/#/R-GGA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Gallus gallus 456216 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus 456216 R-GGA-1638845 https://reactome.org/PathwayBrowser/#/R-GGA-1638845 CERK phosphorylates CERA to form C1P IEA Gallus gallus 456216 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus 456216 R-GGA-164840 https://reactome.org/PathwayBrowser/#/R-GGA-164840 ADP and Pi bind to ATPase IEA Gallus gallus 456216 R-GGA-165692 https://reactome.org/PathwayBrowser/#/R-GGA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Gallus gallus 456216 R-GGA-165718 https://reactome.org/PathwayBrowser/#/R-GGA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Gallus gallus 456216 R-GGA-165726 https://reactome.org/PathwayBrowser/#/R-GGA-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Gallus gallus 456216 R-GGA-165758 https://reactome.org/PathwayBrowser/#/R-GGA-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Gallus gallus 456216 R-GGA-165766 https://reactome.org/PathwayBrowser/#/R-GGA-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Gallus gallus 456216 R-GGA-165777 https://reactome.org/PathwayBrowser/#/R-GGA-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Gallus gallus 456216 R-GGA-166245 https://reactome.org/PathwayBrowser/#/R-GGA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Gallus gallus 456216 R-GGA-1675773 https://reactome.org/PathwayBrowser/#/R-GGA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Gallus gallus 456216 R-GGA-1675776 https://reactome.org/PathwayBrowser/#/R-GGA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Gallus gallus 456216 R-GGA-1675780 https://reactome.org/PathwayBrowser/#/R-GGA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Gallus gallus 456216 R-GGA-1675810 https://reactome.org/PathwayBrowser/#/R-GGA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Gallus gallus 456216 R-GGA-1675813 https://reactome.org/PathwayBrowser/#/R-GGA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Gallus gallus 456216 R-GGA-1675883 https://reactome.org/PathwayBrowser/#/R-GGA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Gallus gallus 456216 R-GGA-1675928 https://reactome.org/PathwayBrowser/#/R-GGA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Gallus gallus 456216 R-GGA-1675939 https://reactome.org/PathwayBrowser/#/R-GGA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Gallus gallus 456216 R-GGA-1675961 https://reactome.org/PathwayBrowser/#/R-GGA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Gallus gallus 456216 R-GGA-1675974 https://reactome.org/PathwayBrowser/#/R-GGA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Gallus gallus 456216 R-GGA-1676024 https://reactome.org/PathwayBrowser/#/R-GGA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Gallus gallus 456216 R-GGA-1676048 https://reactome.org/PathwayBrowser/#/R-GGA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Gallus gallus 456216 R-GGA-1676082 https://reactome.org/PathwayBrowser/#/R-GGA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Gallus gallus 456216 R-GGA-1676109 https://reactome.org/PathwayBrowser/#/R-GGA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Gallus gallus 456216 R-GGA-1676134 https://reactome.org/PathwayBrowser/#/R-GGA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Gallus gallus 456216 R-GGA-1676145 https://reactome.org/PathwayBrowser/#/R-GGA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Gallus gallus 456216 R-GGA-1676185 https://reactome.org/PathwayBrowser/#/R-GGA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Gallus gallus 456216 R-GGA-1676206 https://reactome.org/PathwayBrowser/#/R-GGA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Gallus gallus 456216 R-GGA-1678944 https://reactome.org/PathwayBrowser/#/R-GGA-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Gallus gallus 456216 R-GGA-168053 https://reactome.org/PathwayBrowser/#/R-GGA-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Gallus gallus 456216 R-GGA-168136 https://reactome.org/PathwayBrowser/#/R-GGA-168136 Activated JNKs phosphorylate c-JUN IEA Gallus gallus 456216 R-GGA-168162 https://reactome.org/PathwayBrowser/#/R-GGA-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Gallus gallus 456216 R-GGA-169905 https://reactome.org/PathwayBrowser/#/R-GGA-169905 ARMS is phosphorylated by active TrkA receptor IEA Gallus gallus 456216 R-GGA-170026 https://reactome.org/PathwayBrowser/#/R-GGA-170026 Protons are translocated from the intermembrane space to the matrix IEA Gallus gallus 456216 R-GGA-170087 https://reactome.org/PathwayBrowser/#/R-GGA-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Gallus gallus 456216 R-GGA-170843 https://reactome.org/PathwayBrowser/#/R-GGA-170843 TGFBR2 phosphorylates TGFBR1 IEA Gallus gallus 456216 R-GGA-170868 https://reactome.org/PathwayBrowser/#/R-GGA-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Gallus gallus 456216 R-GGA-170977 https://reactome.org/PathwayBrowser/#/R-GGA-170977 FRS2 is phosphorylated by active TrkA receptor IEA Gallus gallus 456216 R-GGA-174079 https://reactome.org/PathwayBrowser/#/R-GGA-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Gallus gallus 456216 R-GGA-174164 https://reactome.org/PathwayBrowser/#/R-GGA-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Gallus gallus 456216 R-GGA-174174 https://reactome.org/PathwayBrowser/#/R-GGA-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Gallus gallus 456216 R-GGA-174389 https://reactome.org/PathwayBrowser/#/R-GGA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Gallus gallus 456216 R-GGA-174394 https://reactome.org/PathwayBrowser/#/R-GGA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Gallus gallus 456216 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus 456216 R-GGA-176298 https://reactome.org/PathwayBrowser/#/R-GGA-176298 Activation of claspin IEA Gallus gallus 456216 R-GGA-177275 https://reactome.org/PathwayBrowser/#/R-GGA-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Gallus gallus 456216 R-GGA-177284 https://reactome.org/PathwayBrowser/#/R-GGA-177284 PKA phosphorylates PDE4B IEA Gallus gallus 456216 R-GGA-177930 https://reactome.org/PathwayBrowser/#/R-GGA-177930 GAB1 phosphorylation by EGFR kinase IEA Gallus gallus 456216 R-GGA-177933 https://reactome.org/PathwayBrowser/#/R-GGA-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Gallus gallus 456216 R-GGA-177934 https://reactome.org/PathwayBrowser/#/R-GGA-177934 EGFR autophosphorylation IEA Gallus gallus 456216 R-GGA-177937 https://reactome.org/PathwayBrowser/#/R-GGA-177937 Phosphorylation of EGFR by SRC kinase IEA Gallus gallus 456216 R-GGA-177939 https://reactome.org/PathwayBrowser/#/R-GGA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Gallus gallus 456216 R-GGA-182969 https://reactome.org/PathwayBrowser/#/R-GGA-182969 Phosphorylation of CBL (EGFR:CBL) IEA Gallus gallus 456216 R-GGA-183058 https://reactome.org/PathwayBrowser/#/R-GGA-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Gallus gallus 456216 R-GGA-1855153 https://reactome.org/PathwayBrowser/#/R-GGA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Gallus gallus 456216 R-GGA-1855157 https://reactome.org/PathwayBrowser/#/R-GGA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Gallus gallus 456216 R-GGA-1855158 https://reactome.org/PathwayBrowser/#/R-GGA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Gallus gallus 456216 R-GGA-1855162 https://reactome.org/PathwayBrowser/#/R-GGA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Gallus gallus 456216 R-GGA-1855169 https://reactome.org/PathwayBrowser/#/R-GGA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 456216 R-GGA-1855172 https://reactome.org/PathwayBrowser/#/R-GGA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Gallus gallus 456216 R-GGA-1855176 https://reactome.org/PathwayBrowser/#/R-GGA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Gallus gallus 456216 R-GGA-1855179 https://reactome.org/PathwayBrowser/#/R-GGA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Gallus gallus 456216 R-GGA-1855181 https://reactome.org/PathwayBrowser/#/R-GGA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Gallus gallus 456216 R-GGA-1855182 https://reactome.org/PathwayBrowser/#/R-GGA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Gallus gallus 456216 R-GGA-1855185 https://reactome.org/PathwayBrowser/#/R-GGA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 456216 R-GGA-1855193 https://reactome.org/PathwayBrowser/#/R-GGA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Gallus gallus 456216 R-GGA-1855194 https://reactome.org/PathwayBrowser/#/R-GGA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Gallus gallus 456216 R-GGA-1855197 https://reactome.org/PathwayBrowser/#/R-GGA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 456216 R-GGA-1855206 https://reactome.org/PathwayBrowser/#/R-GGA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 456216 R-GGA-1855207 https://reactome.org/PathwayBrowser/#/R-GGA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Gallus gallus 456216 R-GGA-1855216 https://reactome.org/PathwayBrowser/#/R-GGA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Gallus gallus 456216 R-GGA-1855223 https://reactome.org/PathwayBrowser/#/R-GGA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Gallus gallus 456216 R-GGA-1855224 https://reactome.org/PathwayBrowser/#/R-GGA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Gallus gallus 456216 R-GGA-1855227 https://reactome.org/PathwayBrowser/#/R-GGA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Gallus gallus 456216 R-GGA-1855228 https://reactome.org/PathwayBrowser/#/R-GGA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 456216 R-GGA-1855230 https://reactome.org/PathwayBrowser/#/R-GGA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Gallus gallus 456216 R-GGA-1855233 https://reactome.org/PathwayBrowser/#/R-GGA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Gallus gallus 456216 R-GGA-186786 https://reactome.org/PathwayBrowser/#/R-GGA-186786 Autophosphorylation of PDGF beta receptors IEA Gallus gallus 456216 R-GGA-186800 https://reactome.org/PathwayBrowser/#/R-GGA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-187520 https://reactome.org/PathwayBrowser/#/R-GGA-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Gallus gallus 456216 R-GGA-187688 https://reactome.org/PathwayBrowser/#/R-GGA-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Gallus gallus 456216 R-GGA-187916 https://reactome.org/PathwayBrowser/#/R-GGA-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Gallus gallus 456216 R-GGA-187948 https://reactome.org/PathwayBrowser/#/R-GGA-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Gallus gallus 456216 R-GGA-187949 https://reactome.org/PathwayBrowser/#/R-GGA-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Gallus gallus 456216 R-GGA-187959 https://reactome.org/PathwayBrowser/#/R-GGA-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Gallus gallus 456216 R-GGA-188350 https://reactome.org/PathwayBrowser/#/R-GGA-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Gallus gallus 456216 R-GGA-188390 https://reactome.org/PathwayBrowser/#/R-GGA-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Gallus gallus 456216 R-GGA-190326 https://reactome.org/PathwayBrowser/#/R-GGA-190326 Autocatalytic phosphorylation of FGFR4 IEA Gallus gallus 456216 R-GGA-190385 https://reactome.org/PathwayBrowser/#/R-GGA-190385 Autocatalytic phosphorylation of FGFR3b IEA Gallus gallus 456216 R-GGA-190388 https://reactome.org/PathwayBrowser/#/R-GGA-190388 Autocatalytic phosphorylation of FGFR3c IEA Gallus gallus 456216 R-GGA-190408 https://reactome.org/PathwayBrowser/#/R-GGA-190408 Autocatalytic phosphorylation of FGFR2b IEA Gallus gallus 456216 R-GGA-190413 https://reactome.org/PathwayBrowser/#/R-GGA-190413 Autocatalytic phosphorylation of FGFR2c IEA Gallus gallus 456216 R-GGA-190427 https://reactome.org/PathwayBrowser/#/R-GGA-190427 Autocatalytic phosphorylation of FGFR1b IEA Gallus gallus 456216 R-GGA-190429 https://reactome.org/PathwayBrowser/#/R-GGA-190429 Autocatalytic phosphorylation of FGFR1c IEA Gallus gallus 456216 R-GGA-191062 https://reactome.org/PathwayBrowser/#/R-GGA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Gallus gallus 456216 R-GGA-191380 https://reactome.org/PathwayBrowser/#/R-GGA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Gallus gallus 456216 R-GGA-191414 https://reactome.org/PathwayBrowser/#/R-GGA-191414 MVD decarboxylates MVA5PP to IPPP IEA Gallus gallus 456216 R-GGA-191422 https://reactome.org/PathwayBrowser/#/R-GGA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Gallus gallus 456216 R-GGA-191636 https://reactome.org/PathwayBrowser/#/R-GGA-191636 Phosphorylation of Cx43 by c-src IEA Gallus gallus 456216 R-GGA-193362 https://reactome.org/PathwayBrowser/#/R-GGA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Gallus gallus 456216 R-GGA-193703 https://reactome.org/PathwayBrowser/#/R-GGA-193703 IKKbeta is activated IEA Gallus gallus 456216 R-GGA-193705 https://reactome.org/PathwayBrowser/#/R-GGA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Gallus gallus 456216 R-GGA-194153 https://reactome.org/PathwayBrowser/#/R-GGA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Gallus gallus 456216 R-GGA-195275 https://reactome.org/PathwayBrowser/#/R-GGA-195275 Phosphorylation of APC component of the destruction complex IEA Gallus gallus 456216 R-GGA-195283 https://reactome.org/PathwayBrowser/#/R-GGA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Gallus gallus 456216 R-GGA-195287 https://reactome.org/PathwayBrowser/#/R-GGA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Gallus gallus 456216 R-GGA-195300 https://reactome.org/PathwayBrowser/#/R-GGA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Gallus gallus 456216 R-GGA-195318 https://reactome.org/PathwayBrowser/#/R-GGA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Gallus gallus 456216 R-GGA-1963581 https://reactome.org/PathwayBrowser/#/R-GGA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Gallus gallus 456216 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 456216 R-GGA-1963586 https://reactome.org/PathwayBrowser/#/R-GGA-1963586 SRC family kinases phosphorylate ERBB2 IEA Gallus gallus 456216 R-GGA-196773 https://reactome.org/PathwayBrowser/#/R-GGA-196773 COASY phosphorylates DP-CoA IEA Gallus gallus 456216 R-GGA-196857 https://reactome.org/PathwayBrowser/#/R-GGA-196857 PANK2 phosphorylates PanK IEA Gallus gallus 456216 R-GGA-196964 https://reactome.org/PathwayBrowser/#/R-GGA-196964 RFK:Mg2+ phosphorylates RIB IEA Gallus gallus 456216 R-GGA-197198 https://reactome.org/PathwayBrowser/#/R-GGA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Gallus gallus 456216 R-GGA-197958 https://reactome.org/PathwayBrowser/#/R-GGA-197958 FPGS-2 transforms THF to THFPG IEA Gallus gallus 456216 R-GGA-198266 https://reactome.org/PathwayBrowser/#/R-GGA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Gallus gallus 456216 R-GGA-198314 https://reactome.org/PathwayBrowser/#/R-GGA-198314 DAG stimulates protein kinase C-delta IEA Gallus gallus 456216 R-GGA-198599 https://reactome.org/PathwayBrowser/#/R-GGA-198599 AKT phosphorylates MDM2 IEA Gallus gallus 456216 R-GGA-198609 https://reactome.org/PathwayBrowser/#/R-GGA-198609 AKT phosphorylates TSC2, inhibiting it IEA Gallus gallus 456216 R-GGA-198611 https://reactome.org/PathwayBrowser/#/R-GGA-198611 AKT phosphorylates IKKalpha IEA Gallus gallus 456216 R-GGA-198613 https://reactome.org/PathwayBrowser/#/R-GGA-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Gallus gallus 456216 R-GGA-198621 https://reactome.org/PathwayBrowser/#/R-GGA-198621 AKT phosphorylates caspase-9 IEA Gallus gallus 456216 R-GGA-198640 https://reactome.org/PathwayBrowser/#/R-GGA-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Gallus gallus 456216 R-GGA-198669 https://reactome.org/PathwayBrowser/#/R-GGA-198669 p38MAPK phosphorylates MSK1 IEA Gallus gallus 456216 R-GGA-198746 https://reactome.org/PathwayBrowser/#/R-GGA-198746 ERK1/2/5 activate RSK1/2/3 IEA Gallus gallus 456216 R-GGA-198756 https://reactome.org/PathwayBrowser/#/R-GGA-198756 ERK1/2 phosphorylates MSK1 IEA Gallus gallus 456216 R-GGA-199203 https://reactome.org/PathwayBrowser/#/R-GGA-199203 PANK1/3 phosphorylate PanK IEA Gallus gallus 456216 R-GGA-199298 https://reactome.org/PathwayBrowser/#/R-GGA-199298 AKT phosphorylates CREB1 IEA Gallus gallus 456216 R-GGA-199299 https://reactome.org/PathwayBrowser/#/R-GGA-199299 AKT phosphorylates FOXO transcription factors IEA Gallus gallus 456216 R-GGA-199839 https://reactome.org/PathwayBrowser/#/R-GGA-199839 AKT can phosphorylate RSK IEA Gallus gallus 456216 R-GGA-199863 https://reactome.org/PathwayBrowser/#/R-GGA-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Gallus gallus 456216 R-GGA-199895 https://reactome.org/PathwayBrowser/#/R-GGA-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Gallus gallus 456216 R-GGA-199910 https://reactome.org/PathwayBrowser/#/R-GGA-199910 MSK1 activates ATF1 IEA Gallus gallus 456216 R-GGA-199917 https://reactome.org/PathwayBrowser/#/R-GGA-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Gallus gallus 456216 R-GGA-199935 https://reactome.org/PathwayBrowser/#/R-GGA-199935 MSK1 activates CREB IEA Gallus gallus 456216 R-GGA-200318 https://reactome.org/PathwayBrowser/#/R-GGA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Gallus gallus 456216 R-GGA-200326 https://reactome.org/PathwayBrowser/#/R-GGA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Gallus gallus 456216 R-GGA-200421 https://reactome.org/PathwayBrowser/#/R-GGA-200421 Activation of cytosolic AMPK by phosphorylation IEA Gallus gallus 456216 R-GGA-200555 https://reactome.org/PathwayBrowser/#/R-GGA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Gallus gallus 456216 R-GGA-200681 https://reactome.org/PathwayBrowser/#/R-GGA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Gallus gallus 456216 R-GGA-200682 https://reactome.org/PathwayBrowser/#/R-GGA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Gallus gallus 456216 R-GGA-200711 https://reactome.org/PathwayBrowser/#/R-GGA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Gallus gallus 456216 R-GGA-201443 https://reactome.org/PathwayBrowser/#/R-GGA-201443 Type II receptor phosphorylates type I receptor IEA Gallus gallus 456216 R-GGA-201476 https://reactome.org/PathwayBrowser/#/R-GGA-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Gallus gallus 456216 R-GGA-201510 https://reactome.org/PathwayBrowser/#/R-GGA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Gallus gallus 456216 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 456216 R-GGA-201677 https://reactome.org/PathwayBrowser/#/R-GGA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Gallus gallus 456216 R-GGA-202111 https://reactome.org/PathwayBrowser/#/R-GGA-202111 AKT1 phosphorylates eNOS IEA Gallus gallus 456216 R-GGA-202165 https://reactome.org/PathwayBrowser/#/R-GGA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Gallus gallus 456216 R-GGA-202168 https://reactome.org/PathwayBrowser/#/R-GGA-202168 Phosphorylation of ZAP-70 by Lck IEA Gallus gallus 456216 R-GGA-202174 https://reactome.org/PathwayBrowser/#/R-GGA-202174 Activation of ZAP-70 IEA Gallus gallus 456216 R-GGA-202233 https://reactome.org/PathwayBrowser/#/R-GGA-202233 Inactivation of Lck by Csk IEA Gallus gallus 456216 R-GGA-202248 https://reactome.org/PathwayBrowser/#/R-GGA-202248 Phosphorylation of PLC-gamma1 IEA Gallus gallus 456216 R-GGA-202291 https://reactome.org/PathwayBrowser/#/R-GGA-202291 Activation of Lck IEA Gallus gallus 456216 R-GGA-202365 https://reactome.org/PathwayBrowser/#/R-GGA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-202459 https://reactome.org/PathwayBrowser/#/R-GGA-202459 Phosphorylation of Bcl10 IEA Gallus gallus 456216 R-GGA-202510 https://reactome.org/PathwayBrowser/#/R-GGA-202510 Activation of TAK1-TAB2 complex IEA Gallus gallus 456216 R-GGA-2028284 https://reactome.org/PathwayBrowser/#/R-GGA-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Gallus gallus 456216 R-GGA-2028555 https://reactome.org/PathwayBrowser/#/R-GGA-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Gallus gallus 456216 R-GGA-2028583 https://reactome.org/PathwayBrowser/#/R-GGA-2028583 Phosphorylation of YAP by LATS2 IEA Gallus gallus 456216 R-GGA-2028589 https://reactome.org/PathwayBrowser/#/R-GGA-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Gallus gallus 456216 R-GGA-2028591 https://reactome.org/PathwayBrowser/#/R-GGA-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Gallus gallus 456216 R-GGA-2028598 https://reactome.org/PathwayBrowser/#/R-GGA-2028598 Phosphorylation of YAP by LATS1 IEA Gallus gallus 456216 R-GGA-2028629 https://reactome.org/PathwayBrowser/#/R-GGA-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Gallus gallus 456216 R-GGA-2028635 https://reactome.org/PathwayBrowser/#/R-GGA-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Gallus gallus 456216 R-GGA-2028661 https://reactome.org/PathwayBrowser/#/R-GGA-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Gallus gallus 456216 R-GGA-2028670 https://reactome.org/PathwayBrowser/#/R-GGA-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Gallus gallus 456216 R-GGA-2028673 https://reactome.org/PathwayBrowser/#/R-GGA-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Gallus gallus 456216 R-GGA-2028675 https://reactome.org/PathwayBrowser/#/R-GGA-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Gallus gallus 456216 R-GGA-2028679 https://reactome.org/PathwayBrowser/#/R-GGA-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Gallus gallus 456216 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus 456216 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus 456216 R-GGA-2029454 https://reactome.org/PathwayBrowser/#/R-GGA-2029454 Autophosphorylation of PAK1 IEA Gallus gallus 456216 R-GGA-2029459 https://reactome.org/PathwayBrowser/#/R-GGA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Gallus gallus 456216 R-GGA-2029460 https://reactome.org/PathwayBrowser/#/R-GGA-2029460 PAK1 phosphorylates LIMK1 IEA Gallus gallus 456216 R-GGA-2029469 https://reactome.org/PathwayBrowser/#/R-GGA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Gallus gallus 456216 R-GGA-2029473 https://reactome.org/PathwayBrowser/#/R-GGA-2029473 Branching and elongation of mother and daughter filaments IEA Gallus gallus 456216 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus 456216 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 456216 R-GGA-205136 https://reactome.org/PathwayBrowser/#/R-GGA-205136 GTP-bound RAC contributes to JNK activation IEA Gallus gallus 456216 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 456216 R-GGA-2060328 https://reactome.org/PathwayBrowser/#/R-GGA-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Gallus gallus 456216 R-GGA-209087 https://reactome.org/PathwayBrowser/#/R-GGA-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Gallus gallus 456216 R-GGA-210291 https://reactome.org/PathwayBrowser/#/R-GGA-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Gallus gallus 456216 R-GGA-211164 https://reactome.org/PathwayBrowser/#/R-GGA-211164 AKT phosphorylates FOXO1A IEA Gallus gallus 456216 R-GGA-212710 https://reactome.org/PathwayBrowser/#/R-GGA-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Gallus gallus 456216 R-GGA-2130194 https://reactome.org/PathwayBrowser/#/R-GGA-2130194 ABL phosphorylates WAVEs IEA Gallus gallus 456216 R-GGA-216723 https://reactome.org/PathwayBrowser/#/R-GGA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Gallus gallus 456216 R-GGA-216757 https://reactome.org/PathwayBrowser/#/R-GGA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Gallus gallus 456216 R-GGA-2168079 https://reactome.org/PathwayBrowser/#/R-GGA-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Gallus gallus 456216 R-GGA-216941 https://reactome.org/PathwayBrowser/#/R-GGA-216941 Phosphorylation of Chk1 by ATR TAS Gallus gallus 456216 R-GGA-217013 https://reactome.org/PathwayBrowser/#/R-GGA-217013 Phosphorylation of RAD51 by tyrosine kinase Abelson family protein members TAS Gallus gallus 456216 R-GGA-217136 https://reactome.org/PathwayBrowser/#/R-GGA-217136 Phosphorylation of Chk1 by ATM upon DNA damage TAS Gallus gallus 456216 R-GGA-2197690 https://reactome.org/PathwayBrowser/#/R-GGA-2197690 Detachment of WASP/WAVE IEA Gallus gallus 456216 R-GGA-2197698 https://reactome.org/PathwayBrowser/#/R-GGA-2197698 Src phosphorylate WASP,N-WASP IEA Gallus gallus 456216 R-GGA-2214351 https://reactome.org/PathwayBrowser/#/R-GGA-2214351 PLK1 phosphorylates GORASP1 IEA Gallus gallus 456216 R-GGA-2267372 https://reactome.org/PathwayBrowser/#/R-GGA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Gallus gallus 456216 R-GGA-2294580 https://reactome.org/PathwayBrowser/#/R-GGA-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Gallus gallus 456216 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-2395412 https://reactome.org/PathwayBrowser/#/R-GGA-2395412 Phosphorylation of SYK IEA Gallus gallus 456216 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus 456216 R-GGA-2404193 https://reactome.org/PathwayBrowser/#/R-GGA-2404193 IGF1R phosphorylates SHC1 IEA Gallus gallus 456216 R-GGA-2404199 https://reactome.org/PathwayBrowser/#/R-GGA-2404199 IGF1,2:IGF1R autophosphorylates IEA Gallus gallus 456216 R-GGA-2422927 https://reactome.org/PathwayBrowser/#/R-GGA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Gallus gallus 456216 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus 456216 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus 456216 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus 456216 R-GGA-2428926 https://reactome.org/PathwayBrowser/#/R-GGA-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Gallus gallus 456216 R-GGA-2430535 https://reactome.org/PathwayBrowser/#/R-GGA-2430535 MASTL phosphorylates ENSA IEA Gallus gallus 456216 R-GGA-2466068 https://reactome.org/PathwayBrowser/#/R-GGA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Gallus gallus 456216 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus 456216 R-GGA-2468293 https://reactome.org/PathwayBrowser/#/R-GGA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Gallus gallus 456216 R-GGA-2562526 https://reactome.org/PathwayBrowser/#/R-GGA-2562526 PLK1 phosphorylates OPTN IEA Gallus gallus 456216 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus 456216 R-GGA-2581474 https://reactome.org/PathwayBrowser/#/R-GGA-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Gallus gallus 456216 R-GGA-265682 https://reactome.org/PathwayBrowser/#/R-GGA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Gallus gallus 456216 R-GGA-265783 https://reactome.org/PathwayBrowser/#/R-GGA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Gallus gallus 456216 R-GGA-265936 https://reactome.org/PathwayBrowser/#/R-GGA-265936 Phosphorylation of RPA2 by CDC2 kinase TAS Gallus gallus 456216 R-GGA-265951 https://reactome.org/PathwayBrowser/#/R-GGA-265951 Phosphorylation of FANCG at S7 TAS Gallus gallus 456216 R-GGA-265959 https://reactome.org/PathwayBrowser/#/R-GGA-265959 Phosphorylation of Chk2 by ATM upon DNA damage TAS Gallus gallus 456216 R-GGA-265987 https://reactome.org/PathwayBrowser/#/R-GGA-265987 Phosphorylation of BRCA1 IEA Gallus gallus 456216 R-GGA-266082 https://reactome.org/PathwayBrowser/#/R-GGA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Gallus gallus 456216 R-GGA-2682349 https://reactome.org/PathwayBrowser/#/R-GGA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Gallus gallus 456216 R-GGA-2730841 https://reactome.org/PathwayBrowser/#/R-GGA-2730841 Phosphorylation and activation of VAV IEA Gallus gallus 456216 R-GGA-2730856 https://reactome.org/PathwayBrowser/#/R-GGA-2730856 Autophosphorylation of PAK IEA Gallus gallus 456216 R-GGA-2730858 https://reactome.org/PathwayBrowser/#/R-GGA-2730858 Autophosphorylation of BTK/ITK IEA Gallus gallus 456216 R-GGA-2730862 https://reactome.org/PathwayBrowser/#/R-GGA-2730862 Autophosphorylation of LYN kinase IEA Gallus gallus 456216 R-GGA-2730870 https://reactome.org/PathwayBrowser/#/R-GGA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Gallus gallus 456216 R-GGA-2730896 https://reactome.org/PathwayBrowser/#/R-GGA-2730896 Phosphorylation of MEK4 by MEKK1 IEA Gallus gallus 456216 R-GGA-2730900 https://reactome.org/PathwayBrowser/#/R-GGA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Gallus gallus 456216 R-GGA-2984220 https://reactome.org/PathwayBrowser/#/R-GGA-2984220 CDK1:CCNB phosphorylates NEK9 IEA Gallus gallus 456216 R-GGA-2984226 https://reactome.org/PathwayBrowser/#/R-GGA-2984226 PLK1 phosphorylates NEK9 IEA Gallus gallus 456216 R-GGA-2984258 https://reactome.org/PathwayBrowser/#/R-GGA-2984258 NEK9 phosphorylates NEK6/NEK7 IEA Gallus gallus 456216 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus 456216 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus 456216 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus 456216 R-GGA-3000327 https://reactome.org/PathwayBrowser/#/R-GGA-3000327 PLK1 phosphorylates BORA IEA Gallus gallus 456216 R-GGA-3095901 https://reactome.org/PathwayBrowser/#/R-GGA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Gallus gallus 456216 R-GGA-3132737 https://reactome.org/PathwayBrowser/#/R-GGA-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Gallus gallus 456216 R-GGA-3228469 https://reactome.org/PathwayBrowser/#/R-GGA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Gallus gallus 456216 R-GGA-3229102 https://reactome.org/PathwayBrowser/#/R-GGA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Gallus gallus 456216 R-GGA-3238999 https://reactome.org/PathwayBrowser/#/R-GGA-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Gallus gallus 456216 R-GGA-3239019 https://reactome.org/PathwayBrowser/#/R-GGA-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Gallus gallus 456216 R-GGA-3371422 https://reactome.org/PathwayBrowser/#/R-GGA-3371422 ATP hydrolysis by HSP70 IEA Gallus gallus 456216 R-GGA-3371435 https://reactome.org/PathwayBrowser/#/R-GGA-3371435 Constitutive phosphorylation by GSK3 IEA Gallus gallus 456216 R-GGA-3371503 https://reactome.org/PathwayBrowser/#/R-GGA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Gallus gallus 456216 R-GGA-3371531 https://reactome.org/PathwayBrowser/#/R-GGA-3371531 Constitutive phosphorylation by pERK1/2 IEA Gallus gallus 456216 R-GGA-349444 https://reactome.org/PathwayBrowser/#/R-GGA-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Gallus gallus 456216 R-GGA-351434 https://reactome.org/PathwayBrowser/#/R-GGA-351434 Phosphorylation of H2AX at S139 by ATM at the site of DSB TAS Gallus gallus 456216 R-GGA-351455 https://reactome.org/PathwayBrowser/#/R-GGA-351455 Phosphorylation of NBS1 by ATM TAS Gallus gallus 456216 R-GGA-352840 https://reactome.org/PathwayBrowser/#/R-GGA-352840 glucose + ATP => glucose 6-phosphate + ADP TAS Gallus gallus 456216 R-GGA-352908 https://reactome.org/PathwayBrowser/#/R-GGA-352908 fructose 6-phosphate + ATP => fructose 2,6-bisphosphate + ADP TAS Gallus gallus 456216 R-GGA-352945 https://reactome.org/PathwayBrowser/#/R-GGA-352945 fructose 6-phosphate + ATP => fructose 1,6-bisphosphate + ADP TAS Gallus gallus 456216 R-GGA-353023 https://reactome.org/PathwayBrowser/#/R-GGA-353023 3-phosphoglycerate + ATP <=> 1,3-bisphosphoglycerate + ADP TAS Gallus gallus 456216 R-GGA-353039 https://reactome.org/PathwayBrowser/#/R-GGA-353039 1,3-bisphosphoglycerate + ADP <=> 3-phosphoglycerate + ATP TAS Gallus gallus 456216 R-GGA-353056 https://reactome.org/PathwayBrowser/#/R-GGA-353056 phosphoenolpyruvate + ADP => pyruvate + ATP TAS Gallus gallus 456216 R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 456216 R-GGA-353455 https://reactome.org/PathwayBrowser/#/R-GGA-353455 Autophosphorylation of DNA-PKcs IEA Gallus gallus 456216 R-GGA-354073 https://reactome.org/PathwayBrowser/#/R-GGA-354073 Autophosphorylation of PTK2 at Y397 IEA Gallus gallus 456216 R-GGA-354124 https://reactome.org/PathwayBrowser/#/R-GGA-354124 Phosphorylation of pPTK2 by SRC IEA Gallus gallus 456216 R-GGA-372693 https://reactome.org/PathwayBrowser/#/R-GGA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Gallus gallus 456216 R-GGA-372977 https://reactome.org/PathwayBrowser/#/R-GGA-372977 succinylCoA + ADP + Pi <=> succinate + CoASH + ATP TAS Gallus gallus 456216 R-GGA-373134 https://reactome.org/PathwayBrowser/#/R-GGA-373134 succinate + CoASH + ATP <=> succinylCoA + ADP + Pi TAS Gallus gallus 456216 R-GGA-373750 https://reactome.org/PathwayBrowser/#/R-GGA-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Gallus gallus 456216 R-GGA-374701 https://reactome.org/PathwayBrowser/#/R-GGA-374701 Phosphorylation of DCC by Fyn IEA Gallus gallus 456216 R-GGA-3769394 https://reactome.org/PathwayBrowser/#/R-GGA-3769394 AKT phosphorylates CBY1 IEA Gallus gallus 456216 R-GGA-377186 https://reactome.org/PathwayBrowser/#/R-GGA-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Gallus gallus 456216 R-GGA-3772435 https://reactome.org/PathwayBrowser/#/R-GGA-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Gallus gallus 456216 R-GGA-3772436 https://reactome.org/PathwayBrowser/#/R-GGA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Gallus gallus 456216 R-GGA-377640 https://reactome.org/PathwayBrowser/#/R-GGA-377640 Autophosphorylation of SRC IEA Gallus gallus 456216 R-GGA-3788705 https://reactome.org/PathwayBrowser/#/R-GGA-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Gallus gallus 456216 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 456216 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 456216 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus 456216 R-GGA-380780 https://reactome.org/PathwayBrowser/#/R-GGA-380780 Activation of Src IEA Gallus gallus 456216 R-GGA-381091 https://reactome.org/PathwayBrowser/#/R-GGA-381091 IRE1 dimer autophosphorylates IEA Gallus gallus 456216 R-GGA-381111 https://reactome.org/PathwayBrowser/#/R-GGA-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Gallus gallus 456216 R-GGA-382560 https://reactome.org/PathwayBrowser/#/R-GGA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Gallus gallus 456216 R-GGA-382575 https://reactome.org/PathwayBrowser/#/R-GGA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Gallus gallus 456216 R-GGA-383190 https://reactome.org/PathwayBrowser/#/R-GGA-383190 HCO3- transport through ion channel IEA Gallus gallus 456216 R-GGA-3857329 https://reactome.org/PathwayBrowser/#/R-GGA-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Gallus gallus 456216 R-GGA-388831 https://reactome.org/PathwayBrowser/#/R-GGA-388831 Phosphorylation of CD28 IEA Gallus gallus 456216 R-GGA-389083 https://reactome.org/PathwayBrowser/#/R-GGA-389083 Autophosphorylation of PDGF alpha receptors IEA Gallus gallus 456216 R-GGA-389086 https://reactome.org/PathwayBrowser/#/R-GGA-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Gallus gallus 456216 R-GGA-389158 https://reactome.org/PathwayBrowser/#/R-GGA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-389354 https://reactome.org/PathwayBrowser/#/R-GGA-389354 Activation of Vav1 IEA Gallus gallus 456216 R-GGA-389756 https://reactome.org/PathwayBrowser/#/R-GGA-389756 AKT interacts and phosphorylates Cot IEA Gallus gallus 456216 R-GGA-389762 https://reactome.org/PathwayBrowser/#/R-GGA-389762 Phosphorylation of PD-1 IEA Gallus gallus 456216 R-GGA-390593 https://reactome.org/PathwayBrowser/#/R-GGA-390593 ATP Hydrolysis By Myosin IEA Gallus gallus 456216 R-GGA-390597 https://reactome.org/PathwayBrowser/#/R-GGA-390597 Release Of ADP From Myosin IEA Gallus gallus 456216 R-GGA-391266 https://reactome.org/PathwayBrowser/#/R-GGA-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Gallus gallus 456216 R-GGA-392195 https://reactome.org/PathwayBrowser/#/R-GGA-392195 Gi activation by P2Y purinoceptor 12 IEA Gallus gallus 456216 R-GGA-392300 https://reactome.org/PathwayBrowser/#/R-GGA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-392530 https://reactome.org/PathwayBrowser/#/R-GGA-392530 p-S400-Cot phosphorylates NIK IEA Gallus gallus 456216 R-GGA-3928578 https://reactome.org/PathwayBrowser/#/R-GGA-3928578 EPH receptors autophosphorylate IEA Gallus gallus 456216 R-GGA-3928593 https://reactome.org/PathwayBrowser/#/R-GGA-3928593 Sfks phosphorylate EfnB1 TAS Gallus gallus 456216 R-GGA-3928596 https://reactome.org/PathwayBrowser/#/R-GGA-3928596 Phosphorylation of ephexin1 TAS Gallus gallus 456216 R-GGA-3928604 https://reactome.org/PathwayBrowser/#/R-GGA-3928604 SFKs phosphorylate VAV2,3 IEA Gallus gallus 456216 R-GGA-3928620 https://reactome.org/PathwayBrowser/#/R-GGA-3928620 PAK1 autophosphorylates IEA Gallus gallus 456216 R-GGA-3928625 https://reactome.org/PathwayBrowser/#/R-GGA-3928625 PAKs autophosphorylate IEA Gallus gallus 456216 R-GGA-3928627 https://reactome.org/PathwayBrowser/#/R-GGA-3928627 EPHB phosphorylates TIAM1 IEA Gallus gallus 456216 R-GGA-3928640 https://reactome.org/PathwayBrowser/#/R-GGA-3928640 PAKs phosphorylate MLC IEA Gallus gallus 456216 R-GGA-399939 https://reactome.org/PathwayBrowser/#/R-GGA-399939 Autophosphorylation of PAK IEA Gallus gallus 456216 R-GGA-399944 https://reactome.org/PathwayBrowser/#/R-GGA-399944 Phosphorylation of CRMPs by Cdk5 IEA Gallus gallus 456216 R-GGA-399947 https://reactome.org/PathwayBrowser/#/R-GGA-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Gallus gallus 456216 R-GGA-399951 https://reactome.org/PathwayBrowser/#/R-GGA-399951 Phosphorylation of CRMPs by GSK3beta IEA Gallus gallus 456216 R-GGA-399952 https://reactome.org/PathwayBrowser/#/R-GGA-399952 Phosphorylation of LIMK-1 by PAK IEA Gallus gallus 456216 R-GGA-399978 https://reactome.org/PathwayBrowser/#/R-GGA-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Gallus gallus 456216 R-GGA-4085028 https://reactome.org/PathwayBrowser/#/R-GGA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Gallus gallus 456216 R-GGA-4086410 https://reactome.org/PathwayBrowser/#/R-GGA-4086410 CDK1 phosphorylates BORA IEA Gallus gallus 456216 R-GGA-4088024 https://reactome.org/PathwayBrowser/#/R-GGA-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Gallus gallus 456216 R-GGA-4088134 https://reactome.org/PathwayBrowser/#/R-GGA-4088134 PLK1 phosphorylates FOXM1 IEA Gallus gallus 456216 R-GGA-4093332 https://reactome.org/PathwayBrowser/#/R-GGA-4093332 p-EPHB phosphorylates SDC2 IEA Gallus gallus 456216 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus 456216 R-GGA-416985 https://reactome.org/PathwayBrowser/#/R-GGA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Gallus gallus 456216 R-GGA-417843 https://reactome.org/PathwayBrowser/#/R-GGA-417843 P2Y13 binds ADP IEA Gallus gallus 456216 R-GGA-417908 https://reactome.org/PathwayBrowser/#/R-GGA-417908 P2RY1 binds ADP IEA Gallus gallus 456216 R-GGA-418576 https://reactome.org/PathwayBrowser/#/R-GGA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Gallus gallus 456216 R-GGA-419144 https://reactome.org/PathwayBrowser/#/R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate TAS Gallus gallus 456216 R-GGA-419153 https://reactome.org/PathwayBrowser/#/R-GGA-419153 5-phosphoribosylamine + glycine + ATP <=> 5-phosphoribosylglycinamide (GAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 456216 R-GGA-419157 https://reactome.org/PathwayBrowser/#/R-GGA-419157 5'-phosphoribosylformylglycinamidine (FGAM) + ATP => 5'-phosphoribosyl-5-aminoimidazole (AIR) + ADP + orthophosphate TAS Gallus gallus 456216 R-GGA-419223 https://reactome.org/PathwayBrowser/#/R-GGA-419223 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 456216 R-GGA-419440 https://reactome.org/PathwayBrowser/#/R-GGA-419440 L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate IEA Gallus gallus 456216 R-GGA-419644 https://reactome.org/PathwayBrowser/#/R-GGA-419644 Transphosphorylation of pLIMK1 IEA Gallus gallus 456216 R-GGA-419646 https://reactome.org/PathwayBrowser/#/R-GGA-419646 SEMA4D interacts with Plexin-B1:Met IEA Gallus gallus 456216 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus 456216 R-GGA-426240 https://reactome.org/PathwayBrowser/#/R-GGA-426240 DAG kinase produces phosphatidic acid from DAG IEA Gallus gallus 456216 R-GGA-428273 https://reactome.org/PathwayBrowser/#/R-GGA-428273 SPHK1 phosphorylates sphingoid IEA Gallus gallus 456216 R-GGA-428941 https://reactome.org/PathwayBrowser/#/R-GGA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Gallus gallus 456216 R-GGA-428961 https://reactome.org/PathwayBrowser/#/R-GGA-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Gallus gallus 456216 R-GGA-429016 https://reactome.org/PathwayBrowser/#/R-GGA-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Gallus gallus 456216 R-GGA-429157 https://reactome.org/PathwayBrowser/#/R-GGA-429157 ABCC4 accumulation of dense granule contents IEA Gallus gallus 456216 R-GGA-429441 https://reactome.org/PathwayBrowser/#/R-GGA-429441 SYK activation by SRC IEA Gallus gallus 456216 R-GGA-429449 https://reactome.org/PathwayBrowser/#/R-GGA-429449 Syk activation leads to SLP-76 activation IEA Gallus gallus 456216 R-GGA-432129 https://reactome.org/PathwayBrowser/#/R-GGA-432129 FGR binds and phosphorylates LRP8 IEA Gallus gallus 456216 R-GGA-432148 https://reactome.org/PathwayBrowser/#/R-GGA-432148 Fgr may phosphorylate p38 MAPK IEA Gallus gallus 456216 R-GGA-432232 https://reactome.org/PathwayBrowser/#/R-GGA-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Gallus gallus 456216 R-GGA-4332358 https://reactome.org/PathwayBrowser/#/R-GGA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Gallus gallus 456216 R-GGA-4332363 https://reactome.org/PathwayBrowser/#/R-GGA-4332363 Autophosphorylation and activation of CAMK2 IEA Gallus gallus 456216 R-GGA-433606 https://reactome.org/PathwayBrowser/#/R-GGA-433606 sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP IEA Gallus gallus 456216 R-GGA-433786 https://reactome.org/PathwayBrowser/#/R-GGA-433786 Phosphorylation of IRF3 by TBK1 complexed with activated TLR3 IEA Gallus gallus 456216 R-GGA-433804 https://reactome.org/PathwayBrowser/#/R-GGA-433804 IKK epsilon is recruited to the Viral dsRNA:TLR3:TICAM1 complex IEA Gallus gallus 456216 R-GGA-433826 https://reactome.org/PathwayBrowser/#/R-GGA-433826 Phosphorylation of IRF3 by IKK epsilon(IKBKE) complexed with activated TLR3. IEA Gallus gallus 456216 R-GGA-433845 https://reactome.org/PathwayBrowser/#/R-GGA-433845 chicken RIP1 facilitates IKKs complex activation IEA Gallus gallus 456216 R-GGA-433955 https://reactome.org/PathwayBrowser/#/R-GGA-433955 Phosphorylation of IKKs complex by activated TAK1 IEA Gallus gallus 456216 R-GGA-433957 https://reactome.org/PathwayBrowser/#/R-GGA-433957 Activation of recruited TAK1 IEA Gallus gallus 456216 R-GGA-433986 https://reactome.org/PathwayBrowser/#/R-GGA-433986 activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB IEA Gallus gallus 456216 R-GGA-434018 https://reactome.org/PathwayBrowser/#/R-GGA-434018 Autophosphorylation of chicken IRAK4 IEA Gallus gallus 456216 R-GGA-434030 https://reactome.org/PathwayBrowser/#/R-GGA-434030 TBK1 is recruited to the Viral dsRNA:TLR3:TICAM1 complex IEA Gallus gallus 456216 R-GGA-434047 https://reactome.org/PathwayBrowser/#/R-GGA-434047 phosphorylation of IRAK2 by activated IRAK4 IEA Gallus gallus 456216 R-GGA-435244 https://reactome.org/PathwayBrowser/#/R-GGA-435244 PECAM1 is phosphorylated IEA Gallus gallus 456216 R-GGA-437162 https://reactome.org/PathwayBrowser/#/R-GGA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-437984 https://reactome.org/PathwayBrowser/#/R-GGA-437984 Phosphorylation of MKK3/MKK6 by activated TAK1 IEA Gallus gallus 456216 R-GGA-437999 https://reactome.org/PathwayBrowser/#/R-GGA-437999 Phosphorylation of MKK4 by activated TAK1 IEA Gallus gallus 456216 R-GGA-438005 https://reactome.org/PathwayBrowser/#/R-GGA-438005 MKK4 phosphorylates JNK IEA Gallus gallus 456216 R-GGA-438019 https://reactome.org/PathwayBrowser/#/R-GGA-438019 activated chicken MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Gallus gallus 456216 R-GGA-438026 https://reactome.org/PathwayBrowser/#/R-GGA-438026 Activation and dimerization of c-JUN in the nucleus IEA Gallus gallus 456216 R-GGA-4411383 https://reactome.org/PathwayBrowser/#/R-GGA-4411383 NLK phosphorylates TCF/LEF IEA Gallus gallus 456216 R-GGA-4411402 https://reactome.org/PathwayBrowser/#/R-GGA-4411402 Activation of NLK IEA Gallus gallus 456216 R-GGA-4420117 https://reactome.org/PathwayBrowser/#/R-GGA-4420117 VEGFR2 autophosphorylates IEA Gallus gallus 456216 R-GGA-4420121 https://reactome.org/PathwayBrowser/#/R-GGA-4420121 SFKs phosphorylate PLCG1 IEA Gallus gallus 456216 R-GGA-4420128 https://reactome.org/PathwayBrowser/#/R-GGA-4420128 SRC-1 phosphorylates SHB IEA Gallus gallus 456216 R-GGA-4420206 https://reactome.org/PathwayBrowser/#/R-GGA-4420206 Phosphorylation of SRC-1 IEA Gallus gallus 456216 R-GGA-442724 https://reactome.org/PathwayBrowser/#/R-GGA-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Gallus gallus 456216 R-GGA-442913 https://reactome.org/PathwayBrowser/#/R-GGA-442913 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Gallus gallus 456216 R-GGA-443818 https://reactome.org/PathwayBrowser/#/R-GGA-443818 Phosphorylation of L1 by EPHB2 TAS Gallus gallus 456216 R-GGA-445072 https://reactome.org/PathwayBrowser/#/R-GGA-445072 Interaction of PAK1 with Rac1-GTP IEA Gallus gallus 456216 R-GGA-445079 https://reactome.org/PathwayBrowser/#/R-GGA-445079 Phosphorylation of L1 by ERK IEA Gallus gallus 456216 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus 456216 R-GGA-445705 https://reactome.org/PathwayBrowser/#/R-GGA-445705 Release Of ADP From Myosin IEA Gallus gallus 456216 R-GGA-445813 https://reactome.org/PathwayBrowser/#/R-GGA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Gallus gallus 456216 R-GGA-446634 https://reactome.org/PathwayBrowser/#/R-GGA-446634 IRAK4 is activated by autophosphorylation IEA Gallus gallus 456216 R-GGA-447074 https://reactome.org/PathwayBrowser/#/R-GGA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Gallus gallus 456216 R-GGA-448955 https://reactome.org/PathwayBrowser/#/R-GGA-448955 Phosphorylation of MEF2 proteins by p38 IEA Gallus gallus 456216 R-GGA-450222 https://reactome.org/PathwayBrowser/#/R-GGA-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Gallus gallus 456216 R-GGA-450325 https://reactome.org/PathwayBrowser/#/R-GGA-450325 c-FOS activation by phospho ERK1/2 IEA Gallus gallus 456216 R-GGA-450333 https://reactome.org/PathwayBrowser/#/R-GGA-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Gallus gallus 456216 R-GGA-450337 https://reactome.org/PathwayBrowser/#/R-GGA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Gallus gallus 456216 R-GGA-450346 https://reactome.org/PathwayBrowser/#/R-GGA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Gallus gallus 456216 R-GGA-450474 https://reactome.org/PathwayBrowser/#/R-GGA-450474 MK2 phosphorylates BRF1 IEA Gallus gallus 456216 R-GGA-450490 https://reactome.org/PathwayBrowser/#/R-GGA-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Gallus gallus 456216 R-GGA-450533 https://reactome.org/PathwayBrowser/#/R-GGA-450533 PKCdelta phosphorylates HuR IEA Gallus gallus 456216 R-GGA-450550 https://reactome.org/PathwayBrowser/#/R-GGA-450550 PKCalpha phosphorylates HuR IEA Gallus gallus 456216 R-GGA-451447 https://reactome.org/PathwayBrowser/#/R-GGA-451447 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 IEA Gallus gallus 456216 R-GGA-451516 https://reactome.org/PathwayBrowser/#/R-GGA-451516 activated MEK2 phosphorylates ERK2 IEA Gallus gallus 456216 R-GGA-4793911 https://reactome.org/PathwayBrowser/#/R-GGA-4793911 MAPKAPK2 phosphorylates HSF1 IEA Gallus gallus 456216 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 456216 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 456216 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 456216 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 456216 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 456216 R-GGA-504054 https://reactome.org/PathwayBrowser/#/R-GGA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Gallus gallus 456216 R-GGA-508040 https://reactome.org/PathwayBrowser/#/R-GGA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Gallus gallus 456216 R-GGA-5082387 https://reactome.org/PathwayBrowser/#/R-GGA-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Gallus gallus 456216 R-GGA-5082405 https://reactome.org/PathwayBrowser/#/R-GGA-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Gallus gallus 456216 R-GGA-508308 https://reactome.org/PathwayBrowser/#/R-GGA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Gallus gallus 456216 R-GGA-5218640 https://reactome.org/PathwayBrowser/#/R-GGA-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Gallus gallus 456216 R-GGA-5218642 https://reactome.org/PathwayBrowser/#/R-GGA-5218642 PTK2 autophosphorylates IEA Gallus gallus 456216 R-GGA-5218804 https://reactome.org/PathwayBrowser/#/R-GGA-5218804 p38 MAPK activation by VEGFR IEA Gallus gallus 456216 R-GGA-5218805 https://reactome.org/PathwayBrowser/#/R-GGA-5218805 PKC autophosphorylates IEA Gallus gallus 456216 R-GGA-5218806 https://reactome.org/PathwayBrowser/#/R-GGA-5218806 FYN autophosphorylates IEA Gallus gallus 456216 R-GGA-5218809 https://reactome.org/PathwayBrowser/#/R-GGA-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Gallus gallus 456216 R-GGA-5218812 https://reactome.org/PathwayBrowser/#/R-GGA-5218812 FYN phosphorylates PAK2 IEA Gallus gallus 456216 R-GGA-5218814 https://reactome.org/PathwayBrowser/#/R-GGA-5218814 PAK2 autophorylates IEA Gallus gallus 456216 R-GGA-5218819 https://reactome.org/PathwayBrowser/#/R-GGA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-5218820 https://reactome.org/PathwayBrowser/#/R-GGA-5218820 Src kinases phosphorylate VAV IEA Gallus gallus 456216 R-GGA-5218821 https://reactome.org/PathwayBrowser/#/R-GGA-5218821 PDK1 phosphorylates PKC IEA Gallus gallus 456216 R-GGA-5218823 https://reactome.org/PathwayBrowser/#/R-GGA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Gallus gallus 456216 R-GGA-5218826 https://reactome.org/PathwayBrowser/#/R-GGA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Gallus gallus 456216 R-GGA-5218830 https://reactome.org/PathwayBrowser/#/R-GGA-5218830 SRC-1 phosphorylates PTK2-beta IEA Gallus gallus 456216 R-GGA-5218845 https://reactome.org/PathwayBrowser/#/R-GGA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Gallus gallus 456216 R-GGA-5218851 https://reactome.org/PathwayBrowser/#/R-GGA-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Gallus gallus 456216 R-GGA-5218916 https://reactome.org/PathwayBrowser/#/R-GGA-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Gallus gallus 456216 R-GGA-5223313 https://reactome.org/PathwayBrowser/#/R-GGA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Gallus gallus 456216 R-GGA-5223317 https://reactome.org/PathwayBrowser/#/R-GGA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Gallus gallus 456216 R-GGA-5229343 https://reactome.org/PathwayBrowser/#/R-GGA-5229343 AXIN is phosphorylated in the destruction complex IEA Gallus gallus 456216 R-GGA-5251989 https://reactome.org/PathwayBrowser/#/R-GGA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Gallus gallus 456216 R-GGA-5357429 https://reactome.org/PathwayBrowser/#/R-GGA-5357429 AXL autophosphorylates on Y779 and Y821 IEA Gallus gallus 456216 R-GGA-5357472 https://reactome.org/PathwayBrowser/#/R-GGA-5357472 PAK1-3 autophosphorylates IEA Gallus gallus 456216 R-GGA-5357477 https://reactome.org/PathwayBrowser/#/R-GGA-5357477 PAK1-3 phosphorylates VE-cadherin IEA Gallus gallus 456216 R-GGA-5358513 https://reactome.org/PathwayBrowser/#/R-GGA-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Gallus gallus 456216 R-GGA-5358525 https://reactome.org/PathwayBrowser/#/R-GGA-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Gallus gallus 456216 R-GGA-5358912 https://reactome.org/PathwayBrowser/#/R-GGA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Gallus gallus 456216 R-GGA-5362459 https://reactome.org/PathwayBrowser/#/R-GGA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Gallus gallus 456216 R-GGA-5444511 https://reactome.org/PathwayBrowser/#/R-GGA-5444511 Formation of MSH2:MSH3 Complex IEA Gallus gallus 456216 R-GGA-5444516 https://reactome.org/PathwayBrowser/#/R-GGA-5444516 Formation of MSH2:MSH6 Complex IEA Gallus gallus 456216 R-GGA-5607722 https://reactome.org/PathwayBrowser/#/R-GGA-5607722 Active NIK phosphorylates IKKA dimer IEA Gallus gallus 456216 R-GGA-5607726 https://reactome.org/PathwayBrowser/#/R-GGA-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Gallus gallus 456216 R-GGA-5607732 https://reactome.org/PathwayBrowser/#/R-GGA-5607732 K63polyUb-TAK1 autophosphorylates IEA Gallus gallus 456216 R-GGA-5607740 https://reactome.org/PathwayBrowser/#/R-GGA-5607740 PKC-delta phosphorylates CARD9 IEA Gallus gallus 456216 R-GGA-5610720 https://reactome.org/PathwayBrowser/#/R-GGA-5610720 PKA phosphorylates GLI3 IEA Gallus gallus 456216 R-GGA-5610722 https://reactome.org/PathwayBrowser/#/R-GGA-5610722 CK1 phosphorylates p-GLI3 IEA Gallus gallus 456216 R-GGA-5610732 https://reactome.org/PathwayBrowser/#/R-GGA-5610732 GSK3 phosphorylates p-GLI3 IEA Gallus gallus 456216 R-GGA-5618085 https://reactome.org/PathwayBrowser/#/R-GGA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Gallus gallus 456216 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 456216 R-GGA-5618098 https://reactome.org/PathwayBrowser/#/R-GGA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Gallus gallus 456216 R-GGA-5618105 https://reactome.org/PathwayBrowser/#/R-GGA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Gallus gallus 456216 R-GGA-5618107 https://reactome.org/PathwayBrowser/#/R-GGA-5618107 ATP binding to HSP90 triggers conformation change IEA Gallus gallus 456216 R-GGA-5618110 https://reactome.org/PathwayBrowser/#/R-GGA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Gallus gallus 456216 R-GGA-5623667 https://reactome.org/PathwayBrowser/#/R-GGA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Gallus gallus 456216 R-GGA-5624473 https://reactome.org/PathwayBrowser/#/R-GGA-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Gallus gallus 456216 R-GGA-5624486 https://reactome.org/PathwayBrowser/#/R-GGA-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Gallus gallus 456216 R-GGA-5624492 https://reactome.org/PathwayBrowser/#/R-GGA-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Gallus gallus 456216 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus 456216 R-GGA-5627775 https://reactome.org/PathwayBrowser/#/R-GGA-5627775 Autophosphorylation of PAK1,2,3 IEA Gallus gallus 456216 R-GGA-5654147 https://reactome.org/PathwayBrowser/#/R-GGA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Gallus gallus 456216 R-GGA-5654149 https://reactome.org/PathwayBrowser/#/R-GGA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Gallus gallus 456216 R-GGA-5654151 https://reactome.org/PathwayBrowser/#/R-GGA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Gallus gallus 456216 R-GGA-5654222 https://reactome.org/PathwayBrowser/#/R-GGA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Gallus gallus 456216 R-GGA-5654397 https://reactome.org/PathwayBrowser/#/R-GGA-5654397 Activated FGFR2 phosphorylates FRS2 IEA Gallus gallus 456216 R-GGA-5654407 https://reactome.org/PathwayBrowser/#/R-GGA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Gallus gallus 456216 R-GGA-5654408 https://reactome.org/PathwayBrowser/#/R-GGA-5654408 Activated FGFR3 phosphorylates FRS2 IEA Gallus gallus 456216 R-GGA-5654418 https://reactome.org/PathwayBrowser/#/R-GGA-5654418 Activated FGFR4 phosphorylates FRS2 IEA Gallus gallus 456216 R-GGA-5654428 https://reactome.org/PathwayBrowser/#/R-GGA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Gallus gallus 456216 R-GGA-5654560 https://reactome.org/PathwayBrowser/#/R-GGA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Gallus gallus 456216 R-GGA-5654562 https://reactome.org/PathwayBrowser/#/R-GGA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Gallus gallus 456216 R-GGA-5654565 https://reactome.org/PathwayBrowser/#/R-GGA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Gallus gallus 456216 R-GGA-5654566 https://reactome.org/PathwayBrowser/#/R-GGA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Gallus gallus 456216 R-GGA-5654575 https://reactome.org/PathwayBrowser/#/R-GGA-5654575 Activated FGFR1 phosphorylates FRS2 IEA Gallus gallus 456216 R-GGA-5654578 https://reactome.org/PathwayBrowser/#/R-GGA-5654578 Activated FGFR1 phosphorylates FRS3 IEA Gallus gallus 456216 R-GGA-5654582 https://reactome.org/PathwayBrowser/#/R-GGA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Gallus gallus 456216 R-GGA-5654587 https://reactome.org/PathwayBrowser/#/R-GGA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Gallus gallus 456216 R-GGA-5654605 https://reactome.org/PathwayBrowser/#/R-GGA-5654605 Activated FGFR2 phosphorylates FRS3 IEA Gallus gallus 456216 R-GGA-5654607 https://reactome.org/PathwayBrowser/#/R-GGA-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Gallus gallus 456216 R-GGA-5654628 https://reactome.org/PathwayBrowser/#/R-GGA-5654628 Activated FGFR3 phosphorylates FRS3 IEA Gallus gallus 456216 R-GGA-5654631 https://reactome.org/PathwayBrowser/#/R-GGA-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Gallus gallus 456216 R-GGA-5654634 https://reactome.org/PathwayBrowser/#/R-GGA-5654634 Activated FGFR3 phosphorylates SHC1 IEA Gallus gallus 456216 R-GGA-5654653 https://reactome.org/PathwayBrowser/#/R-GGA-5654653 Activated FGFR4 phosphorylates FRS3 IEA Gallus gallus 456216 R-GGA-5654655 https://reactome.org/PathwayBrowser/#/R-GGA-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Gallus gallus 456216 R-GGA-5654690 https://reactome.org/PathwayBrowser/#/R-GGA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-5654692 https://reactome.org/PathwayBrowser/#/R-GGA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-5654697 https://reactome.org/PathwayBrowser/#/R-GGA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-5654701 https://reactome.org/PathwayBrowser/#/R-GGA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-5654705 https://reactome.org/PathwayBrowser/#/R-GGA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-5654709 https://reactome.org/PathwayBrowser/#/R-GGA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-5654714 https://reactome.org/PathwayBrowser/#/R-GGA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-5654717 https://reactome.org/PathwayBrowser/#/R-GGA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 456216 R-GGA-5654989 https://reactome.org/PathwayBrowser/#/R-GGA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Gallus gallus 456216 R-GGA-5662466 https://reactome.org/PathwayBrowser/#/R-GGA-5662466 XYLB phosphorylates D-xylulose IEA Gallus gallus 456216 R-GGA-5665868 https://reactome.org/PathwayBrowser/#/R-GGA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Gallus gallus 456216 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus 456216 R-GGA-5668545 https://reactome.org/PathwayBrowser/#/R-GGA-5668545 NIK autophosphorylates on T559 IEA Gallus gallus 456216 R-GGA-5668932 https://reactome.org/PathwayBrowser/#/R-GGA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Gallus gallus 456216 R-GGA-5668947 https://reactome.org/PathwayBrowser/#/R-GGA-5668947 PAK1 phosphorylates myosin phosphatase IEA Gallus gallus 456216 R-GGA-5668984 https://reactome.org/PathwayBrowser/#/R-GGA-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Gallus gallus 456216 R-GGA-5672008 https://reactome.org/PathwayBrowser/#/R-GGA-5672008 Thr-180 of ULK1 is phosphorylated IEA Gallus gallus 456216 R-GGA-5672010 https://reactome.org/PathwayBrowser/#/R-GGA-5672010 Active MTORC1 phosphorylates ULK1 IEA Gallus gallus 456216 R-GGA-5672012 https://reactome.org/PathwayBrowser/#/R-GGA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Gallus gallus 456216 R-GGA-5672828 https://reactome.org/PathwayBrowser/#/R-GGA-5672828 mTORC1 phosphorylates AKT1S1 IEA Gallus gallus 456216 R-GGA-5672969 https://reactome.org/PathwayBrowser/#/R-GGA-5672969 Phosphorylation of RAF IEA Gallus gallus 456216 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 456216 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 456216 R-GGA-5673768 https://reactome.org/PathwayBrowser/#/R-GGA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Gallus gallus 456216 R-GGA-5674373 https://reactome.org/PathwayBrowser/#/R-GGA-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Gallus gallus 456216 R-GGA-5675194 https://reactome.org/PathwayBrowser/#/R-GGA-5675194 Activated MAPK phosphorylates RAF1 IEA Gallus gallus 456216 R-GGA-5675198 https://reactome.org/PathwayBrowser/#/R-GGA-5675198 Activated MAPKs phosphorylate BRAF IEA Gallus gallus 456216 R-GGA-5675868 https://reactome.org/PathwayBrowser/#/R-GGA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Gallus gallus 456216 R-GGA-5678706 https://reactome.org/PathwayBrowser/#/R-GGA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Gallus gallus 456216 R-GGA-5678863 https://reactome.org/PathwayBrowser/#/R-GGA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Gallus gallus 456216 R-GGA-5679041 https://reactome.org/PathwayBrowser/#/R-GGA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Gallus gallus 456216 R-GGA-5679205 https://reactome.org/PathwayBrowser/#/R-GGA-5679205 ULK1 phosphorylates Beclin-1 IEA Gallus gallus 456216 R-GGA-5682026 https://reactome.org/PathwayBrowser/#/R-GGA-5682026 MRN bound to shortened telomeres activates ATM IEA Gallus gallus 456216 R-GGA-5682101 https://reactome.org/PathwayBrowser/#/R-GGA-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Gallus gallus 456216 R-GGA-5682285 https://reactome.org/PathwayBrowser/#/R-GGA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Gallus gallus 456216 R-GGA-5682598 https://reactome.org/PathwayBrowser/#/R-GGA-5682598 ATM phosphorylates HERC2 IEA Gallus gallus 456216 R-GGA-5682983 https://reactome.org/PathwayBrowser/#/R-GGA-5682983 ATM phosphorylates WHSC1 IEA Gallus gallus 456216 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus 456216 R-GGA-5683714 https://reactome.org/PathwayBrowser/#/R-GGA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Gallus gallus 456216 R-GGA-5683792 https://reactome.org/PathwayBrowser/#/R-GGA-5683792 p-T68-CHEK2 autophosphorylates IEA Gallus gallus 456216 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus 456216 R-GGA-5683930 https://reactome.org/PathwayBrowser/#/R-GGA-5683930 WICH phosphorylates H2AFX on Y142 IEA Gallus gallus 456216 R-GGA-5683964 https://reactome.org/PathwayBrowser/#/R-GGA-5683964 ATM phosphorylates EYA1-4 IEA Gallus gallus 456216 R-GGA-5684096 https://reactome.org/PathwayBrowser/#/R-GGA-5684096 CDK2 phosphorylates RBBP8 IEA Gallus gallus 456216 R-GGA-5684140 https://reactome.org/PathwayBrowser/#/R-GGA-5684140 ATM phosphorylates RBBP8 IEA Gallus gallus 456216 R-GGA-5684261 https://reactome.org/PathwayBrowser/#/R-GGA-5684261 MAP3K8 is phosphorylated IEA Gallus gallus 456216 R-GGA-5685156 https://reactome.org/PathwayBrowser/#/R-GGA-5685156 ATR phosphorylates RPA2 IEA Gallus gallus 456216 R-GGA-5686578 https://reactome.org/PathwayBrowser/#/R-GGA-5686578 Activated ATM phosphorylates ABL1 IEA Gallus gallus 456216 R-GGA-5686587 https://reactome.org/PathwayBrowser/#/R-GGA-5686587 ABL1 phosphorylates RAD52 IEA Gallus gallus 456216 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus 456216 R-GGA-5687086 https://reactome.org/PathwayBrowser/#/R-GGA-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Gallus gallus 456216 R-GGA-5687088 https://reactome.org/PathwayBrowser/#/R-GGA-5687088 PKA phosphorylates MAPKAPK5 IEA Gallus gallus 456216 R-GGA-5687090 https://reactome.org/PathwayBrowser/#/R-GGA-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Gallus gallus 456216 R-GGA-5687094 https://reactome.org/PathwayBrowser/#/R-GGA-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Gallus gallus 456216 R-GGA-5687101 https://reactome.org/PathwayBrowser/#/R-GGA-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Gallus gallus 456216 R-GGA-5687121 https://reactome.org/PathwayBrowser/#/R-GGA-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Gallus gallus 456216 R-GGA-5687183 https://reactome.org/PathwayBrowser/#/R-GGA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Gallus gallus 456216 R-GGA-5690250 https://reactome.org/PathwayBrowser/#/R-GGA-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Gallus gallus 456216 R-GGA-5690996 https://reactome.org/PathwayBrowser/#/R-GGA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Gallus gallus 456216 R-GGA-5692462 https://reactome.org/PathwayBrowser/#/R-GGA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Gallus gallus 456216 R-GGA-5692480 https://reactome.org/PathwayBrowser/#/R-GGA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Gallus gallus 456216 R-GGA-5692755 https://reactome.org/PathwayBrowser/#/R-GGA-5692755 CDK1 phosphorylates MAPK6 IEA Gallus gallus 456216 R-GGA-5692768 https://reactome.org/PathwayBrowser/#/R-GGA-5692768 MAPKAPK5 phosphorylates KALRN IEA Gallus gallus 456216 R-GGA-5692775 https://reactome.org/PathwayBrowser/#/R-GGA-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Gallus gallus 456216 R-GGA-5692779 https://reactome.org/PathwayBrowser/#/R-GGA-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Gallus gallus 456216 R-GGA-5693536 https://reactome.org/PathwayBrowser/#/R-GGA-5693536 ATM phosphorylates MDC1 IEA Gallus gallus 456216 R-GGA-5693540 https://reactome.org/PathwayBrowser/#/R-GGA-5693540 MRN activates ATM IEA Gallus gallus 456216 R-GGA-5693549 https://reactome.org/PathwayBrowser/#/R-GGA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Gallus gallus 456216 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus 456216 R-GGA-5693575 https://reactome.org/PathwayBrowser/#/R-GGA-5693575 DNA-PKcs autophosphorylates IEA Gallus gallus 456216 R-GGA-5693598 https://reactome.org/PathwayBrowser/#/R-GGA-5693598 ATM phosphorylates NBN IEA Gallus gallus 456216 R-GGA-5696021 https://reactome.org/PathwayBrowser/#/R-GGA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Gallus gallus 456216 R-GGA-5696074 https://reactome.org/PathwayBrowser/#/R-GGA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Gallus gallus 456216 R-GGA-5696839 https://reactome.org/PathwayBrowser/#/R-GGA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Gallus gallus 456216 R-GGA-571316 https://reactome.org/PathwayBrowser/#/R-GGA-571316 Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. IEA Gallus gallus 456216 R-GGA-571327 https://reactome.org/PathwayBrowser/#/R-GGA-571327 IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex IEA Gallus gallus 456216 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus 456216 R-GGA-6784006 https://reactome.org/PathwayBrowser/#/R-GGA-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Gallus gallus 456216 R-GGA-6784319 https://reactome.org/PathwayBrowser/#/R-GGA-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Gallus gallus 456216 R-GGA-6784324 https://reactome.org/PathwayBrowser/#/R-GGA-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Gallus gallus 456216 R-GGA-6786050 https://reactome.org/PathwayBrowser/#/R-GGA-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Gallus gallus 456216 R-GGA-6786095 https://reactome.org/PathwayBrowser/#/R-GGA-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Gallus gallus 456216 R-GGA-6786096 https://reactome.org/PathwayBrowser/#/R-GGA-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Gallus gallus 456216 R-GGA-6786245 https://reactome.org/PathwayBrowser/#/R-GGA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Gallus gallus 456216 R-GGA-6788392 https://reactome.org/PathwayBrowser/#/R-GGA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Gallus gallus 456216 R-GGA-6788582 https://reactome.org/PathwayBrowser/#/R-GGA-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Gallus gallus 456216 R-GGA-6788798 https://reactome.org/PathwayBrowser/#/R-GGA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 456216 R-GGA-6788810 https://reactome.org/PathwayBrowser/#/R-GGA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 456216 R-GGA-6788855 https://reactome.org/PathwayBrowser/#/R-GGA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Gallus gallus 456216 R-GGA-6788867 https://reactome.org/PathwayBrowser/#/R-GGA-6788867 FN3K phosphorylates ketosamines IEA Gallus gallus 456216 R-GGA-6793661 https://reactome.org/PathwayBrowser/#/R-GGA-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Gallus gallus 456216 R-GGA-6795290 https://reactome.org/PathwayBrowser/#/R-GGA-6795290 TORC2 complex phosphorylates SGK1 IEA Gallus gallus 456216 R-GGA-6795460 https://reactome.org/PathwayBrowser/#/R-GGA-6795460 SGK1 phosphorylates MDM2 IEA Gallus gallus 456216 R-GGA-6795473 https://reactome.org/PathwayBrowser/#/R-GGA-6795473 PDPK1 phosphorylates SGK1 IEA Gallus gallus 456216 R-GGA-6797606 https://reactome.org/PathwayBrowser/#/R-GGA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Gallus gallus 456216 R-GGA-6798174 https://reactome.org/PathwayBrowser/#/R-GGA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Gallus gallus 456216 R-GGA-6798372 https://reactome.org/PathwayBrowser/#/R-GGA-6798372 ATM phosphorylates DYRK2 IEA Gallus gallus 456216 R-GGA-6799097 https://reactome.org/PathwayBrowser/#/R-GGA-6799097 ATM phosphorylates ZNF420 IEA Gallus gallus 456216 R-GGA-6799495 https://reactome.org/PathwayBrowser/#/R-GGA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Gallus gallus 456216 R-GGA-6801342 https://reactome.org/PathwayBrowser/#/R-GGA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Gallus gallus 456216 R-GGA-6801456 https://reactome.org/PathwayBrowser/#/R-GGA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Gallus gallus 456216 R-GGA-6801666 https://reactome.org/PathwayBrowser/#/R-GGA-6801666 PLK2 phosphorylates CENPJ IEA Gallus gallus 456216 R-GGA-6801675 https://reactome.org/PathwayBrowser/#/R-GGA-6801675 PLK2 phosphorylates NPM1 IEA Gallus gallus 456216 R-GGA-6803545 https://reactome.org/PathwayBrowser/#/R-GGA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Gallus gallus 456216 R-GGA-6803771 https://reactome.org/PathwayBrowser/#/R-GGA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Gallus gallus 456216 R-GGA-6804955 https://reactome.org/PathwayBrowser/#/R-GGA-6804955 ATM phosphorylates MDM2 IEA Gallus gallus 456216 R-GGA-6805507 https://reactome.org/PathwayBrowser/#/R-GGA-6805507 APAF1 binds AVEN IEA Gallus gallus 456216 R-GGA-6805640 https://reactome.org/PathwayBrowser/#/R-GGA-6805640 AKT phosphorylates KAT6A IEA Gallus gallus 456216 R-GGA-6805785 https://reactome.org/PathwayBrowser/#/R-GGA-6805785 AKT phosphorylates PHF20 IEA Gallus gallus 456216 R-GGA-6806877 https://reactome.org/PathwayBrowser/#/R-GGA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Gallus gallus 456216 R-GGA-6806967 https://reactome.org/PathwayBrowser/#/R-GGA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Gallus gallus 456216 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 456216 R-GGA-6807868 https://reactome.org/PathwayBrowser/#/R-GGA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Gallus gallus 456216 R-GGA-6810233 https://reactome.org/PathwayBrowser/#/R-GGA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Gallus gallus 456216 R-GGA-6810472 https://reactome.org/PathwayBrowser/#/R-GGA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Gallus gallus 456216 R-GGA-6811522 https://reactome.org/PathwayBrowser/#/R-GGA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Gallus gallus 456216 R-GGA-6814119 https://reactome.org/PathwayBrowser/#/R-GGA-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Gallus gallus 456216 R-GGA-6814120 https://reactome.org/PathwayBrowser/#/R-GGA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Gallus gallus 456216 R-GGA-6814121 https://reactome.org/PathwayBrowser/#/R-GGA-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Gallus gallus 456216 R-GGA-6814124 https://reactome.org/PathwayBrowser/#/R-GGA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Gallus gallus 456216 R-GGA-6814670 https://reactome.org/PathwayBrowser/#/R-GGA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Gallus gallus 456216 R-GGA-6814683 https://reactome.org/PathwayBrowser/#/R-GGA-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Gallus gallus 456216 R-GGA-68944 https://reactome.org/PathwayBrowser/#/R-GGA-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Gallus gallus 456216 R-GGA-68954 https://reactome.org/PathwayBrowser/#/R-GGA-68954 Mcm2-7 is phosphorylated by DDK IEA Gallus gallus 456216 R-GGA-69005 https://reactome.org/PathwayBrowser/#/R-GGA-69005 Cdc6 protein is phosphorylated by CDK IEA Gallus gallus 456216 R-GGA-69063 https://reactome.org/PathwayBrowser/#/R-GGA-69063 Loading of PCNA - Sliding Clamp Formation IEA Gallus gallus 456216 R-GGA-69195 https://reactome.org/PathwayBrowser/#/R-GGA-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Gallus gallus 456216 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 456216 R-GGA-69608 https://reactome.org/PathwayBrowser/#/R-GGA-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Gallus gallus 456216 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus 456216 R-GGA-70333 https://reactome.org/PathwayBrowser/#/R-GGA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Gallus gallus 456216 R-GGA-70349 https://reactome.org/PathwayBrowser/#/R-GGA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Gallus gallus 456216 R-GGA-70355 https://reactome.org/PathwayBrowser/#/R-GGA-70355 GALK1 phosphorylates Gal to Gal1P IEA Gallus gallus 456216 R-GGA-70420 https://reactome.org/PathwayBrowser/#/R-GGA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Gallus gallus 456216 R-GGA-70467 https://reactome.org/PathwayBrowser/#/R-GGA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Gallus gallus 456216 R-GGA-70486 https://reactome.org/PathwayBrowser/#/R-GGA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Gallus gallus 456216 R-GGA-70555 https://reactome.org/PathwayBrowser/#/R-GGA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Gallus gallus 456216 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Gallus gallus 456216 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Gallus gallus 456216 R-GGA-70606 https://reactome.org/PathwayBrowser/#/R-GGA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Gallus gallus 456216 R-GGA-70773 https://reactome.org/PathwayBrowser/#/R-GGA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Gallus gallus 456216 R-GGA-70997 https://reactome.org/PathwayBrowser/#/R-GGA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Gallus gallus 456216 R-GGA-71031 https://reactome.org/PathwayBrowser/#/R-GGA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Gallus gallus 456216 R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus 456216 R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 456216 R-GGA-71802 https://reactome.org/PathwayBrowser/#/R-GGA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Gallus gallus 456216 R-GGA-71850 https://reactome.org/PathwayBrowser/#/R-GGA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Gallus gallus 456216 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus 456216 R-GGA-727819 https://reactome.org/PathwayBrowser/#/R-GGA-727819 TAK1 phosphorylates MKK6 IEA Gallus gallus 456216 R-GGA-73548 https://reactome.org/PathwayBrowser/#/R-GGA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Gallus gallus 456216 R-GGA-73598 https://reactome.org/PathwayBrowser/#/R-GGA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Gallus gallus 456216 R-GGA-73599 https://reactome.org/PathwayBrowser/#/R-GGA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Gallus gallus 456216 R-GGA-73632 https://reactome.org/PathwayBrowser/#/R-GGA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Gallus gallus 456216 R-GGA-73635 https://reactome.org/PathwayBrowser/#/R-GGA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Gallus gallus 456216 R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus 456216 R-GGA-73788 https://reactome.org/PathwayBrowser/#/R-GGA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Gallus gallus 456216 R-GGA-73805 https://reactome.org/PathwayBrowser/#/R-GGA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Gallus gallus 456216 R-GGA-73810 https://reactome.org/PathwayBrowser/#/R-GGA-73810 FGAM + ATP => AIR + ADP + Pi IEA Gallus gallus 456216 R-GGA-73814 https://reactome.org/PathwayBrowser/#/R-GGA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Gallus gallus 456216 R-GGA-74220 https://reactome.org/PathwayBrowser/#/R-GGA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Gallus gallus 456216 R-GGA-74711 https://reactome.org/PathwayBrowser/#/R-GGA-74711 Phosphorylation of IRS IEA Gallus gallus 456216 R-GGA-74715 https://reactome.org/PathwayBrowser/#/R-GGA-74715 Autophosphorylation of insulin receptor IEA Gallus gallus 456216 R-GGA-74742 https://reactome.org/PathwayBrowser/#/R-GGA-74742 Phosphorylation of SHC1 IEA Gallus gallus 456216 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 456216 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 456216 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 456216 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 456216 R-GGA-75125 https://reactome.org/PathwayBrowser/#/R-GGA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Gallus gallus 456216 R-GGA-75126 https://reactome.org/PathwayBrowser/#/R-GGA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Gallus gallus 456216 R-GGA-75848 https://reactome.org/PathwayBrowser/#/R-GGA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Gallus gallus 456216 R-GGA-75851 https://reactome.org/PathwayBrowser/#/R-GGA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Gallus gallus 456216 R-GGA-75887 https://reactome.org/PathwayBrowser/#/R-GGA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Gallus gallus 456216 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus 456216 R-GGA-77071 https://reactome.org/PathwayBrowser/#/R-GGA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Gallus gallus 456216 R-GGA-873918 https://reactome.org/PathwayBrowser/#/R-GGA-873918 Transphosphorylation of JAK1 IEA Gallus gallus 456216 R-GGA-873919 https://reactome.org/PathwayBrowser/#/R-GGA-873919 Phosphorylation of JAK2 IEA Gallus gallus 456216 R-GGA-873922 https://reactome.org/PathwayBrowser/#/R-GGA-873922 Phosphorylation of STAT1 by JAK kinases IEA Gallus gallus 456216 R-GGA-873924 https://reactome.org/PathwayBrowser/#/R-GGA-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Gallus gallus 456216 R-GGA-879907 https://reactome.org/PathwayBrowser/#/R-GGA-879907 Tyrosine kinases phosphorylate the receptor IEA Gallus gallus 456216 R-GGA-879909 https://reactome.org/PathwayBrowser/#/R-GGA-879909 Activation of STAT5a/b by JAK2 IEA Gallus gallus 456216 R-GGA-879910 https://reactome.org/PathwayBrowser/#/R-GGA-879910 JAK2 is phosphorylated, activated IEA Gallus gallus 456216 R-GGA-8847638 https://reactome.org/PathwayBrowser/#/R-GGA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Gallus gallus 456216 R-GGA-8847977 https://reactome.org/PathwayBrowser/#/R-GGA-8847977 FRK phosphorylates PTEN IEA Gallus gallus 456216 R-GGA-8848053 https://reactome.org/PathwayBrowser/#/R-GGA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Gallus gallus 456216 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus 456216 R-GGA-8850527 https://reactome.org/PathwayBrowser/#/R-GGA-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Gallus gallus 456216 R-GGA-8850529 https://reactome.org/PathwayBrowser/#/R-GGA-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Gallus gallus 456216 R-GGA-8850534 https://reactome.org/PathwayBrowser/#/R-GGA-8850534 PDCL promotes G-protein beta 5 folding IEA Gallus gallus 456216 R-GGA-8850539 https://reactome.org/PathwayBrowser/#/R-GGA-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Gallus gallus 456216 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 456216 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 456216 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 456216 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 456216 R-GGA-8851797 https://reactome.org/PathwayBrowser/#/R-GGA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Gallus gallus 456216 R-GGA-8851890 https://reactome.org/PathwayBrowser/#/R-GGA-8851890 MET phosphorylates SHC1-2 IEA Gallus gallus 456216 R-GGA-8851933 https://reactome.org/PathwayBrowser/#/R-GGA-8851933 MET phosphorylates GAB1 IEA Gallus gallus 456216 R-GGA-8852019 https://reactome.org/PathwayBrowser/#/R-GGA-8852019 MET bound PI3K generates PIP3 IEA Gallus gallus 456216 R-GGA-8852317 https://reactome.org/PathwayBrowser/#/R-GGA-8852317 PLK1 phosphorylates GTSE1 IEA Gallus gallus 456216 R-GGA-8852552 https://reactome.org/PathwayBrowser/#/R-GGA-8852552 MST1R autophosphorylates IEA Gallus gallus 456216 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus 456216 R-GGA-8853444 https://reactome.org/PathwayBrowser/#/R-GGA-8853444 AURKA phosphorylates PHLDA1 IEA Gallus gallus 456216 R-GGA-8853774 https://reactome.org/PathwayBrowser/#/R-GGA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Gallus gallus 456216 R-GGA-8853792 https://reactome.org/PathwayBrowser/#/R-GGA-8853792 RET tyrosine phosphorylation IEA Gallus gallus 456216 R-GGA-8855237 https://reactome.org/PathwayBrowser/#/R-GGA-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Gallus gallus 456216 R-GGA-8856813 https://reactome.org/PathwayBrowser/#/R-GGA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Gallus gallus 456216 R-GGA-8857555 https://reactome.org/PathwayBrowser/#/R-GGA-8857555 EGFR phosphorylates GPNMB IEA Gallus gallus 456216 R-GGA-8857577 https://reactome.org/PathwayBrowser/#/R-GGA-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Gallus gallus 456216 R-GGA-8857583 https://reactome.org/PathwayBrowser/#/R-GGA-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Gallus gallus 456216 R-GGA-8866542 https://reactome.org/PathwayBrowser/#/R-GGA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Gallus gallus 456216 R-GGA-8867041 https://reactome.org/PathwayBrowser/#/R-GGA-8867041 EGFR phosphorylates EPS15 IEA Gallus gallus 456216 R-GGA-8868066 https://reactome.org/PathwayBrowser/#/R-GGA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Gallus gallus 456216 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus 456216 R-GGA-8868118 https://reactome.org/PathwayBrowser/#/R-GGA-8868118 MAPK12 phosphorylates PTPN3 IEA Gallus gallus 456216 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus 456216 R-GGA-8869606 https://reactome.org/PathwayBrowser/#/R-GGA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Gallus gallus 456216 R-GGA-8869607 https://reactome.org/PathwayBrowser/#/R-GGA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Gallus gallus 456216 R-GGA-8869627 https://reactome.org/PathwayBrowser/#/R-GGA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Gallus gallus 456216 R-GGA-8869633 https://reactome.org/PathwayBrowser/#/R-GGA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Gallus gallus 456216 R-GGA-8871373 https://reactome.org/PathwayBrowser/#/R-GGA-8871373 BMX phosphorylates RUFY1 IEA Gallus gallus 456216 R-GGA-8874078 https://reactome.org/PathwayBrowser/#/R-GGA-8874078 PTK2 autophosphorylates IEA Gallus gallus 456216 R-GGA-8874080 https://reactome.org/PathwayBrowser/#/R-GGA-8874080 SRC phosphorylates PTK2 IEA Gallus gallus 456216 R-GGA-8874082 https://reactome.org/PathwayBrowser/#/R-GGA-8874082 MET phosphorylates PTK2 IEA Gallus gallus 456216 R-GGA-8875451 https://reactome.org/PathwayBrowser/#/R-GGA-8875451 MET phosphorylates CBL IEA Gallus gallus 456216 R-GGA-8875817 https://reactome.org/PathwayBrowser/#/R-GGA-8875817 MET phosphorylates STAT3 IEA Gallus gallus 456216 R-GGA-8876446 https://reactome.org/PathwayBrowser/#/R-GGA-8876446 p-ULK1 phosphorylates DENND3 IEA Gallus gallus 456216 R-GGA-8877691 https://reactome.org/PathwayBrowser/#/R-GGA-8877691 MAP2K6 phosphorylates PIP4K2B IEA Gallus gallus 456216 R-GGA-8878050 https://reactome.org/PathwayBrowser/#/R-GGA-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Gallus gallus 456216 R-GGA-8878054 https://reactome.org/PathwayBrowser/#/R-GGA-8878054 HIPK2 phosphorylates RUNX1 IEA Gallus gallus 456216 R-GGA-8931653 https://reactome.org/PathwayBrowser/#/R-GGA-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Gallus gallus 456216 R-GGA-8933446 https://reactome.org/PathwayBrowser/#/R-GGA-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Gallus gallus 456216 R-GGA-8934446 https://reactome.org/PathwayBrowser/#/R-GGA-8934446 Activated PKC phosphorylates SHC1 IEA Gallus gallus 456216 R-GGA-8937807 https://reactome.org/PathwayBrowser/#/R-GGA-8937807 SRC phosphorylates RUNX3 IEA Gallus gallus 456216 R-GGA-8940100 https://reactome.org/PathwayBrowser/#/R-GGA-8940100 CDK1 phosphorylates VCPIP1 IEA Gallus gallus 456216 R-GGA-8942575 https://reactome.org/PathwayBrowser/#/R-GGA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Gallus gallus 456216 R-GGA-8942607 https://reactome.org/PathwayBrowser/#/R-GGA-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Gallus gallus 456216 R-GGA-8942836 https://reactome.org/PathwayBrowser/#/R-GGA-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Gallus gallus 456216 R-GGA-8944454 https://reactome.org/PathwayBrowser/#/R-GGA-8944454 mTORC1 phosphorylates MAF1 IEA Gallus gallus 456216 R-GGA-8948143 https://reactome.org/PathwayBrowser/#/R-GGA-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Gallus gallus 456216 R-GGA-8948146 https://reactome.org/PathwayBrowser/#/R-GGA-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Gallus gallus 456216 R-GGA-8948757 https://reactome.org/PathwayBrowser/#/R-GGA-8948757 AKT phosphorylates MKRN1 IEA Gallus gallus 456216 R-GGA-8950269 https://reactome.org/PathwayBrowser/#/R-GGA-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Gallus gallus 456216 R-GGA-8950405 https://reactome.org/PathwayBrowser/#/R-GGA-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Gallus gallus 456216 R-GGA-8950423 https://reactome.org/PathwayBrowser/#/R-GGA-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Gallus gallus 456216 R-GGA-8950453 https://reactome.org/PathwayBrowser/#/R-GGA-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Gallus gallus 456216 R-GGA-8950757 https://reactome.org/PathwayBrowser/#/R-GGA-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Gallus gallus 456216 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus 456216 R-GGA-8954327 https://reactome.org/PathwayBrowser/#/R-GGA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Gallus gallus 456216 R-GGA-8955030 https://reactome.org/PathwayBrowser/#/R-GGA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Gallus gallus 456216 R-GGA-8955844 https://reactome.org/PathwayBrowser/#/R-GGA-8955844 RBKS phosphorylates ribose to R5P IEA Gallus gallus 456216 R-GGA-8956659 https://reactome.org/PathwayBrowser/#/R-GGA-8956659 ABL1 phosphorylates YAP1 IEA Gallus gallus 456216 R-GGA-8959719 https://reactome.org/PathwayBrowser/#/R-GGA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Gallus gallus 456216 R-GGA-8964242 https://reactome.org/PathwayBrowser/#/R-GGA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Gallus gallus 456216 R-GGA-8982163 https://reactome.org/PathwayBrowser/#/R-GGA-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Gallus gallus 456216 R-GGA-8983059 https://reactome.org/PathwayBrowser/#/R-GGA-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Gallus gallus 456216 R-GGA-8983063 https://reactome.org/PathwayBrowser/#/R-GGA-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Gallus gallus 456216 R-GGA-8983834 https://reactome.org/PathwayBrowser/#/R-GGA-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Gallus gallus 456216 R-GGA-8983835 https://reactome.org/PathwayBrowser/#/R-GGA-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Gallus gallus 456216 R-GGA-8983870 https://reactome.org/PathwayBrowser/#/R-GGA-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Gallus gallus 456216 R-GGA-8983872 https://reactome.org/PathwayBrowser/#/R-GGA-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Gallus gallus 456216 R-GGA-8984014 https://reactome.org/PathwayBrowser/#/R-GGA-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Gallus gallus 456216 R-GGA-8985914 https://reactome.org/PathwayBrowser/#/R-GGA-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Gallus gallus 456216 R-GGA-8985973 https://reactome.org/PathwayBrowser/#/R-GGA-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Gallus gallus 456216 R-GGA-8985988 https://reactome.org/PathwayBrowser/#/R-GGA-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Gallus gallus 456216 R-GGA-8986985 https://reactome.org/PathwayBrowser/#/R-GGA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Gallus gallus 456216 R-GGA-8986994 https://reactome.org/PathwayBrowser/#/R-GGA-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Gallus gallus 456216 R-GGA-8986995 https://reactome.org/PathwayBrowser/#/R-GGA-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Gallus gallus 456216 R-GGA-8987012 https://reactome.org/PathwayBrowser/#/R-GGA-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Gallus gallus 456216 R-GGA-8987040 https://reactome.org/PathwayBrowser/#/R-GGA-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Gallus gallus 456216 R-GGA-8987042 https://reactome.org/PathwayBrowser/#/R-GGA-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Gallus gallus 456216 R-GGA-8987070 https://reactome.org/PathwayBrowser/#/R-GGA-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Gallus gallus 456216 R-GGA-8987084 https://reactome.org/PathwayBrowser/#/R-GGA-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Gallus gallus 456216 R-GGA-8987096 https://reactome.org/PathwayBrowser/#/R-GGA-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Gallus gallus 456216 R-GGA-8987129 https://reactome.org/PathwayBrowser/#/R-GGA-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Gallus gallus 456216 R-GGA-8987141 https://reactome.org/PathwayBrowser/#/R-GGA-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Gallus gallus 456216 R-GGA-8987150 https://reactome.org/PathwayBrowser/#/R-GGA-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Gallus gallus 456216 R-GGA-8987179 https://reactome.org/PathwayBrowser/#/R-GGA-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Gallus gallus 456216 R-GGA-8987202 https://reactome.org/PathwayBrowser/#/R-GGA-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Gallus gallus 456216 R-GGA-8987255 https://reactome.org/PathwayBrowser/#/R-GGA-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Gallus gallus 456216 R-GGA-9006850 https://reactome.org/PathwayBrowser/#/R-GGA-9006850 IL21 receptor JAK phosphorylation IEA Gallus gallus 456216 R-GGA-9006870 https://reactome.org/PathwayBrowser/#/R-GGA-9006870 IL21 receptor STAT phosphorylation IEA Gallus gallus 456216 R-GGA-9008043 https://reactome.org/PathwayBrowser/#/R-GGA-9008043 MAPK8 phosphorylation IEA Gallus gallus 456216 R-GGA-9008684 https://reactome.org/PathwayBrowser/#/R-GGA-9008684 TBK1 phosphorylation IEA Gallus gallus 456216 R-GGA-9009072 https://reactome.org/PathwayBrowser/#/R-GGA-9009072 STAT3 phosphorylation IEA Gallus gallus 456216 R-GGA-9012319 https://reactome.org/PathwayBrowser/#/R-GGA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Gallus gallus 456216 R-GGA-9018572 https://reactome.org/PathwayBrowser/#/R-GGA-9018572 EGFR phosphorylates NOTCH3 IEA Gallus gallus 456216 R-GGA-9021357 https://reactome.org/PathwayBrowser/#/R-GGA-9021357 PRKCI phosphorylates ELF3 IEA Gallus gallus 456216 R-GGA-9021609 https://reactome.org/PathwayBrowser/#/R-GGA-9021609 ESR-associated SRC autophosphorylates IEA Gallus gallus 456216 R-GGA-9033499 https://reactome.org/PathwayBrowser/#/R-GGA-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Gallus gallus 456216 R-GGA-9034714 https://reactome.org/PathwayBrowser/#/R-GGA-9034714 NTRK3 dimers trans-autophosphorylate IEA Gallus gallus 456216 R-GGA-9038161 https://reactome.org/PathwayBrowser/#/R-GGA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Gallus gallus 456216 R-GGA-909552 https://reactome.org/PathwayBrowser/#/R-GGA-909552 Phosphorylation of STAT1 at Ser727 IEA Gallus gallus 456216 R-GGA-909718 https://reactome.org/PathwayBrowser/#/R-GGA-909718 Formation of p-STAT1 homodimer IEA Gallus gallus 456216 R-GGA-909729 https://reactome.org/PathwayBrowser/#/R-GGA-909729 Activation of JAK kinases IEA Gallus gallus 456216 R-GGA-909730 https://reactome.org/PathwayBrowser/#/R-GGA-909730 Phosphorylation of INFAR1 by TYK2 IEA Gallus gallus 456216 R-GGA-909732 https://reactome.org/PathwayBrowser/#/R-GGA-909732 Phosphorylation of STAT2 IEA Gallus gallus 456216 R-GGA-912527 https://reactome.org/PathwayBrowser/#/R-GGA-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Gallus gallus 456216 R-GGA-913996 https://reactome.org/PathwayBrowser/#/R-GGA-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Gallus gallus 456216 R-GGA-917693 https://reactome.org/PathwayBrowser/#/R-GGA-917693 ESCRT Disassembly IEA Gallus gallus 456216 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus 456216 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus 456216 R-GGA-936802 https://reactome.org/PathwayBrowser/#/R-GGA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Gallus gallus 456216 R-GGA-936883 https://reactome.org/PathwayBrowser/#/R-GGA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Gallus gallus 456216 R-GGA-936895 https://reactome.org/PathwayBrowser/#/R-GGA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Gallus gallus 456216 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 456216 R-GGA-936951 https://reactome.org/PathwayBrowser/#/R-GGA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Gallus gallus 456216 R-GGA-936991 https://reactome.org/PathwayBrowser/#/R-GGA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Gallus gallus 456216 R-GGA-937311 https://reactome.org/PathwayBrowser/#/R-GGA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Gallus gallus 456216 R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus 456216 R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus 456216 R-GGA-9603420 https://reactome.org/PathwayBrowser/#/R-GGA-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Gallus gallus 456216 R-GGA-9604328 https://reactome.org/PathwayBrowser/#/R-GGA-9604328 AKT1 phosphorylates NOTCH4 IEA Gallus gallus 456216 R-GGA-9606884 https://reactome.org/PathwayBrowser/#/R-GGA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Gallus gallus 456216 R-GGA-9607039 https://reactome.org/PathwayBrowser/#/R-GGA-9607039 LYN,SYK phosphorylate BTK TAS Gallus gallus 456216 R-GGA-9610153 https://reactome.org/PathwayBrowser/#/R-GGA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Gallus gallus 456216 R-GGA-9610156 https://reactome.org/PathwayBrowser/#/R-GGA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Gallus gallus 456216 R-GGA-9610163 https://reactome.org/PathwayBrowser/#/R-GGA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Gallus gallus 456216 R-GGA-9612501 https://reactome.org/PathwayBrowser/#/R-GGA-9612501 SGK phosphorylates CREB1 IEA Gallus gallus 456216 R-GGA-9612509 https://reactome.org/PathwayBrowser/#/R-GGA-9612509 SGK phosphorylates SRF IEA Gallus gallus 456216 R-GGA-9624526 https://reactome.org/PathwayBrowser/#/R-GGA-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Gallus gallus 456216 R-GGA-9624800 https://reactome.org/PathwayBrowser/#/R-GGA-9624800 CDK1 phosphorylates LBR IEA Gallus gallus 456216 R-GGA-9625487 https://reactome.org/PathwayBrowser/#/R-GGA-9625487 PTK2 autophosphorylates downstream of EGFR IEA Gallus gallus 456216 R-GGA-9626817 https://reactome.org/PathwayBrowser/#/R-GGA-9626817 PKC phosphorylates NCF1 IEA Gallus gallus 456216 R-GGA-9626832 https://reactome.org/PathwayBrowser/#/R-GGA-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Gallus gallus 456216 R-GGA-9626880 https://reactome.org/PathwayBrowser/#/R-GGA-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Gallus gallus 456216 R-GGA-9627089 https://reactome.org/PathwayBrowser/#/R-GGA-9627089 CASP9 is phosphorylated at T412 IEA Gallus gallus 456216 R-GGA-9632858 https://reactome.org/PathwayBrowser/#/R-GGA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Gallus gallus 456216 R-GGA-9632868 https://reactome.org/PathwayBrowser/#/R-GGA-9632868 CDKN1B is phosphorylated in response to estrogen IEA Gallus gallus 456216 R-GGA-9634702 https://reactome.org/PathwayBrowser/#/R-GGA-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Gallus gallus 456216 R-GGA-9645442 https://reactome.org/PathwayBrowser/#/R-GGA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Gallus gallus 456216 R-GGA-9645535 https://reactome.org/PathwayBrowser/#/R-GGA-9645535 ALPK1 phosphorylates TIFA IEA Gallus gallus 456216 R-GGA-9648089 https://reactome.org/PathwayBrowser/#/R-GGA-9648089 NEK6 and NEK7 phosphorylate EML4 IEA Gallus gallus 456216 R-GGA-964958 https://reactome.org/PathwayBrowser/#/R-GGA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Gallus gallus 456216 R-GGA-964962 https://reactome.org/PathwayBrowser/#/R-GGA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Gallus gallus 456216 R-GGA-964970 https://reactome.org/PathwayBrowser/#/R-GGA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Gallus gallus 456216 R-GGA-9650858 https://reactome.org/PathwayBrowser/#/R-GGA-9650858 Meglitinides bind ABCC8 IEA Gallus gallus 456216 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 456216 R-GGA-9653503 https://reactome.org/PathwayBrowser/#/R-GGA-9653503 KRAS4B is phosphorylated on serine 181 IEA Gallus gallus 456216 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 456216 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus 456216 R-GGA-9699579 https://reactome.org/PathwayBrowser/#/R-GGA-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Gallus gallus 456216 R-GGA-9700168 https://reactome.org/PathwayBrowser/#/R-GGA-9700168 Active ALK phosphorylates IRS1 IEA Gallus gallus 456216 R-GGA-9700171 https://reactome.org/PathwayBrowser/#/R-GGA-9700171 Active ALK phosphorylates PLCG1 IEA Gallus gallus 456216 R-GGA-9700175 https://reactome.org/PathwayBrowser/#/R-GGA-9700175 Active ALK phosphorylates SHC1 IEA Gallus gallus 456216 R-GGA-9706399 https://reactome.org/PathwayBrowser/#/R-GGA-9706399 RHOBTB3 hydrolyzes ATP IEA Gallus gallus 456216 R-GGA-9731111 https://reactome.org/PathwayBrowser/#/R-GGA-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Gallus gallus 456216 R-GGA-9732738 https://reactome.org/PathwayBrowser/#/R-GGA-9732738 JAK1-mediated phosphorylation of RAF1 IEA Gallus gallus 456216 R-GGA-9732753 https://reactome.org/PathwayBrowser/#/R-GGA-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Gallus gallus 456216 R-GGA-9734547 https://reactome.org/PathwayBrowser/#/R-GGA-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Gallus gallus 456216 R-GGA-9734687 https://reactome.org/PathwayBrowser/#/R-GGA-9734687 ORC6 is phosphorylated on T195 IEA Gallus gallus 456216 R-GGA-9748949 https://reactome.org/PathwayBrowser/#/R-GGA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Gallus gallus 456216 R-GGA-9748963 https://reactome.org/PathwayBrowser/#/R-GGA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Gallus gallus 456216 R-GGA-9748969 https://reactome.org/PathwayBrowser/#/R-GGA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Gallus gallus 456216 R-GGA-9748999 https://reactome.org/PathwayBrowser/#/R-GGA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Gallus gallus 456216 R-GGA-9750546 https://reactome.org/PathwayBrowser/#/R-GGA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 456216 R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 456216 R-GGA-9750656 https://reactome.org/PathwayBrowser/#/R-GGA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Gallus gallus 456216 R-GGA-975103 https://reactome.org/PathwayBrowser/#/R-GGA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Gallus gallus 456216 R-GGA-9753278 https://reactome.org/PathwayBrowser/#/R-GGA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 456216 R-GGA-9753283 https://reactome.org/PathwayBrowser/#/R-GGA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 456216 R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 456216 R-GGA-9754974 https://reactome.org/PathwayBrowser/#/R-GGA-9754974 ADK phosphorylates RBV IEA Gallus gallus 456216 R-GGA-9755013 https://reactome.org/PathwayBrowser/#/R-GGA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Gallus gallus 456216 R-GGA-9759206 https://reactome.org/PathwayBrowser/#/R-GGA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Gallus gallus 456216 R-GGA-9759454 https://reactome.org/PathwayBrowser/#/R-GGA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Gallus gallus 456216 R-GGA-9759461 https://reactome.org/PathwayBrowser/#/R-GGA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Gallus gallus 456216 R-GGA-9760094 https://reactome.org/PathwayBrowser/#/R-GGA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Gallus gallus 456216 R-GGA-9762094 https://reactome.org/PathwayBrowser/#/R-GGA-9762094 GSK3B phosphorylates p-NFE2L2 IEA Gallus gallus 456216 R-GGA-977239 https://reactome.org/PathwayBrowser/#/R-GGA-977239 Activated IRAK4 bound to activated TLR : MyD88 complex phosphorylates IRAK2 IEA Gallus gallus 456216 R-GGA-977250 https://reactome.org/PathwayBrowser/#/R-GGA-977250 Autophosphorylation of IRAK4 bound to activated TLR5 or 15 IEA Gallus gallus 456216 R-GGA-9796053 https://reactome.org/PathwayBrowser/#/R-GGA-9796053 PRKCI phosphorylates NFE2L2 IEA Gallus gallus 456216 R-GGA-9796067 https://reactome.org/PathwayBrowser/#/R-GGA-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Gallus gallus 456216 R-GGA-9815501 https://reactome.org/PathwayBrowser/#/R-GGA-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 IEA Gallus gallus 456216 R-GGA-9817397 https://reactome.org/PathwayBrowser/#/R-GGA-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Gallus gallus 456216 R-GGA-9819106 https://reactome.org/PathwayBrowser/#/R-GGA-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Gallus gallus 456216 R-GGA-9823906 https://reactome.org/PathwayBrowser/#/R-GGA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Gallus gallus 456216 R-GGA-9824882 https://reactome.org/PathwayBrowser/#/R-GGA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Gallus gallus 456216 R-GGA-9824977 https://reactome.org/PathwayBrowser/#/R-GGA-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Gallus gallus 456216 R-GGA-9824994 https://reactome.org/PathwayBrowser/#/R-GGA-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Gallus gallus 456216 R-GGA-9824995 https://reactome.org/PathwayBrowser/#/R-GGA-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Gallus gallus 456216 R-GGA-9824999 https://reactome.org/PathwayBrowser/#/R-GGA-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Gallus gallus 456216 R-GGA-9825759 https://reactome.org/PathwayBrowser/#/R-GGA-9825759 MAPK-dependent phosphorylation of KARS IEA Gallus gallus 456216 R-GGA-982807 https://reactome.org/PathwayBrowser/#/R-GGA-982807 JAK2 phosphorylation of GHR IEA Gallus gallus 456216 R-GGA-982810 https://reactome.org/PathwayBrowser/#/R-GGA-982810 JAK2 phosphorylation IEA Gallus gallus 456216 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus 456216 R-GGA-9836184 https://reactome.org/PathwayBrowser/#/R-GGA-9836184 p-PKR dimer phosphorylates CDK1 IEA Gallus gallus 456216 R-GGA-9836322 https://reactome.org/PathwayBrowser/#/R-GGA-9836322 p-PKR dimer phosphorylates MKK6 IEA Gallus gallus 456216 R-GGA-9836383 https://reactome.org/PathwayBrowser/#/R-GGA-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Gallus gallus 456216 R-GGA-9836435 https://reactome.org/PathwayBrowser/#/R-GGA-9836435 p-PKR dimer phosphorylates SNCA IEA Gallus gallus 456216 R-GGA-9836515 https://reactome.org/PathwayBrowser/#/R-GGA-9836515 p-PKR dimer phosphorylates PTPN2 IEA Gallus gallus 456216 R-GGA-9836617 https://reactome.org/PathwayBrowser/#/R-GGA-9836617 p-PKR dimer phosphorylates SPHK1 IEA Gallus gallus 456216 R-GGA-983703 https://reactome.org/PathwayBrowser/#/R-GGA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Gallus gallus 456216 R-GGA-983707 https://reactome.org/PathwayBrowser/#/R-GGA-983707 SYK autophosphorylates at the activated BCR IEA Gallus gallus 456216 R-GGA-9837333 https://reactome.org/PathwayBrowser/#/R-GGA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Gallus gallus 456216 R-GGA-9837337 https://reactome.org/PathwayBrowser/#/R-GGA-9837337 DCAKD phosphorylates DP-CoA IEA Gallus gallus 456216 R-GGA-9838004 https://reactome.org/PathwayBrowser/#/R-GGA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Gallus gallus 456216 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus 456216 R-GGA-9839059 https://reactome.org/PathwayBrowser/#/R-GGA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Gallus gallus 456216 R-GGA-9839105 https://reactome.org/PathwayBrowser/#/R-GGA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Gallus gallus 456216 R-GGA-9839113 https://reactome.org/PathwayBrowser/#/R-GGA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Gallus gallus 456216 R-GGA-9842648 https://reactome.org/PathwayBrowser/#/R-GGA-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 IEA Gallus gallus 456216 R-GGA-9842651 https://reactome.org/PathwayBrowser/#/R-GGA-9842651 Active LTK receptor phosphorylates SHC1 IEA Gallus gallus 456216 R-GGA-9842666 https://reactome.org/PathwayBrowser/#/R-GGA-9842666 Active LTK phosphorylates IRS1 IEA Gallus gallus 456216 R-GGA-9843721 https://reactome.org/PathwayBrowser/#/R-GGA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Gallus gallus 456216 R-GGA-9851972 https://reactome.org/PathwayBrowser/#/R-GGA-9851972 PLK1 phosphorylates FIRRM at S43 IEA Gallus gallus 456216 R-GGA-9853369 https://reactome.org/PathwayBrowser/#/R-GGA-9853369 PLK1 phosphorylates FIRMM at S744 IEA Gallus gallus 456216 R-GGA-9861642 https://reactome.org/PathwayBrowser/#/R-GGA-9861642 NEK1 phosphorylates ME1 IEA Gallus gallus 456216 R-GGA-994000 https://reactome.org/PathwayBrowser/#/R-GGA-994000 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation IEA Gallus gallus 456216 R-GGA-994137 https://reactome.org/PathwayBrowser/#/R-GGA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Gallus gallus 456216 R-GGA-994140 https://reactome.org/PathwayBrowser/#/R-GGA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Gallus gallus 456216 R-HSA-1008248 https://reactome.org/PathwayBrowser/#/R-HSA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase TAS Homo sapiens 456216 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 456216 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 456216 R-HSA-109415 https://reactome.org/PathwayBrowser/#/R-HSA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] TAS Homo sapiens 456216 R-HSA-109624 https://reactome.org/PathwayBrowser/#/R-HSA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) TAS Homo sapiens 456216 R-HSA-109671 https://reactome.org/PathwayBrowser/#/R-HSA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) TAS Homo sapiens 456216 R-HSA-109699 https://reactome.org/PathwayBrowser/#/R-HSA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-109702 https://reactome.org/PathwayBrowser/#/R-HSA-109702 PDPK1 phosphorylates AKT2 TAS Homo sapiens 456216 R-HSA-109759 https://reactome.org/PathwayBrowser/#/R-HSA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] TAS Homo sapiens 456216 R-HSA-109822 https://reactome.org/PathwayBrowser/#/R-HSA-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 TAS Homo sapiens 456216 R-HSA-109823 https://reactome.org/PathwayBrowser/#/R-HSA-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 TAS Homo sapiens 456216 R-HSA-109860 https://reactome.org/PathwayBrowser/#/R-HSA-109860 MAP2K1 phosphorylates MAPK3 TAS Homo sapiens 456216 R-HSA-109862 https://reactome.org/PathwayBrowser/#/R-HSA-109862 MAP2K2 phosphorylates MAPK1 TAS Homo sapiens 456216 R-HSA-109903 https://reactome.org/PathwayBrowser/#/R-HSA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] TAS Homo sapiens 456216 R-HSA-110133 https://reactome.org/PathwayBrowser/#/R-HSA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) TAS Homo sapiens 456216 R-HSA-110137 https://reactome.org/PathwayBrowser/#/R-HSA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP TAS Homo sapiens 456216 R-HSA-110138 https://reactome.org/PathwayBrowser/#/R-HSA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 456216 R-HSA-110141 https://reactome.org/PathwayBrowser/#/R-HSA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) TAS Homo sapiens 456216 R-HSA-110144 https://reactome.org/PathwayBrowser/#/R-HSA-110144 ADP + ADP <=> AMP + ATP [AK2] TAS Homo sapiens 456216 R-HSA-110145 https://reactome.org/PathwayBrowser/#/R-HSA-110145 AMP + ATP <=> ADP + ADP [AK2] TAS Homo sapiens 456216 R-HSA-1112510 https://reactome.org/PathwayBrowser/#/R-HSA-1112510 IL6ST is tyrosine phosphorylated TAS Homo sapiens 456216 R-HSA-1112514 https://reactome.org/PathwayBrowser/#/R-HSA-1112514 JAK activation TAS Homo sapiens 456216 R-HSA-1112602 https://reactome.org/PathwayBrowser/#/R-HSA-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor TAS Homo sapiens 456216 R-HSA-1112703 https://reactome.org/PathwayBrowser/#/R-HSA-1112703 PTPN11 is phosphorylated TAS Homo sapiens 456216 R-HSA-1112727 https://reactome.org/PathwayBrowser/#/R-HSA-1112727 Serine phosphorylation of STATs TAS Homo sapiens 456216 R-HSA-111898 https://reactome.org/PathwayBrowser/#/R-HSA-111898 Phosphorylation of cPLA2 by ERK-2 TAS Homo sapiens 456216 R-HSA-111912 https://reactome.org/PathwayBrowser/#/R-HSA-111912 CaMK4 phosphorylates CREB1 IEA Homo sapiens 456216 R-HSA-111915 https://reactome.org/PathwayBrowser/#/R-HSA-111915 CAMK4 autophosphorylates TAS Homo sapiens 456216 R-HSA-111919 https://reactome.org/PathwayBrowser/#/R-HSA-111919 PKA phosphorylates CREB1 IEA Homo sapiens 456216 R-HSA-111970 https://reactome.org/PathwayBrowser/#/R-HSA-111970 PKC phosphorylates GRK2 TAS Homo sapiens 456216 R-HSA-112333 https://reactome.org/PathwayBrowser/#/R-HSA-112333 SRC autophosphorylation is positively regulated by InlA-bound CDH1 TAS Homo sapiens 456216 R-HSA-112342 https://reactome.org/PathwayBrowser/#/R-HSA-112342 Inactivation of MAP2K1 by CDK1 TAS Homo sapiens 456216 R-HSA-112381 https://reactome.org/PathwayBrowser/#/R-HSA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex TAS Homo sapiens 456216 R-HSA-114252 https://reactome.org/PathwayBrowser/#/R-HSA-114252 Cleavage of Procaspase-3 by the apoptosome TAS Homo sapiens 456216 R-HSA-114254 https://reactome.org/PathwayBrowser/#/R-HSA-114254 CYCS binds to APAF1 TAS Homo sapiens 456216 R-HSA-114259 https://reactome.org/PathwayBrowser/#/R-HSA-114259 Cleavage of Procaspase‑9 to caspase‑9 TAS Homo sapiens 456216 R-HSA-114261 https://reactome.org/PathwayBrowser/#/R-HSA-114261 Cleavage of Procaspase-7 by the apoptosome TAS Homo sapiens 456216 R-HSA-114600 https://reactome.org/PathwayBrowser/#/R-HSA-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma TAS Homo sapiens 456216 R-HSA-114683 https://reactome.org/PathwayBrowser/#/R-HSA-114683 Phosphorylation of Platelet Sec-1 TAS Homo sapiens 456216 R-HSA-114684 https://reactome.org/PathwayBrowser/#/R-HSA-114684 Phosphorylation of Syntaxin-4 TAS Homo sapiens 456216 R-HSA-1168374 https://reactome.org/PathwayBrowser/#/R-HSA-1168374 RasGRP1 and RasGRP3 binds diacylglycerol and is phosphorylated IEA Homo sapiens 456216 R-HSA-1168394 https://reactome.org/PathwayBrowser/#/R-HSA-1168394 STAT5 tyrosine phosphorylation IEA Homo sapiens 456216 R-HSA-1168423 https://reactome.org/PathwayBrowser/#/R-HSA-1168423 JAK2 phosphorylation of IRS-1/2 IEA Homo sapiens 456216 R-HSA-1168459 https://reactome.org/PathwayBrowser/#/R-HSA-1168459 Lyn activates ERK TAS Homo sapiens 456216 R-HSA-1168635 https://reactome.org/PathwayBrowser/#/R-HSA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 TAS Homo sapiens 456216 R-HSA-1168638 https://reactome.org/PathwayBrowser/#/R-HSA-1168638 Activated IKK phosphorylates I-kappaB TAS Homo sapiens 456216 R-HSA-1168641 https://reactome.org/PathwayBrowser/#/R-HSA-1168641 TAK1 associated with the CBM complex phosphorylates IKKbeta IEA Homo sapiens 456216 R-HSA-1168767 https://reactome.org/PathwayBrowser/#/R-HSA-1168767 JAK2 phosphorylates STAT1/STAT3 IEA Homo sapiens 456216 R-HSA-1169421 https://reactome.org/PathwayBrowser/#/R-HSA-1169421 Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers TAS Homo sapiens 456216 R-HSA-1181149 https://reactome.org/PathwayBrowser/#/R-HSA-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin TAS Homo sapiens 456216 R-HSA-1181156 https://reactome.org/PathwayBrowser/#/R-HSA-1181156 Type II Activin Receptor (ActRII/ACVR2) phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in response to NODAL IEA Homo sapiens 456216 R-HSA-1181355 https://reactome.org/PathwayBrowser/#/R-HSA-1181355 Phosphorylation of R-SMAD2/3 by NODAL receptor IEA Homo sapiens 456216 R-HSA-1225894 https://reactome.org/PathwayBrowser/#/R-HSA-1225894 Type II Activin Receptor (ActRIIB/ACVR2B) phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in response to NODAL IEA Homo sapiens 456216 R-HSA-1225952 https://reactome.org/PathwayBrowser/#/R-HSA-1225952 Phosphorylation of SHC1 by ligand-responsive p-6Y-EGFR mutants TAS Homo sapiens 456216 R-HSA-1225960 https://reactome.org/PathwayBrowser/#/R-HSA-1225960 Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants TAS Homo sapiens 456216 R-HSA-1226014 https://reactome.org/PathwayBrowser/#/R-HSA-1226014 Conversion of PIP2 to PIP3 by PI3K bound to ligand-responsive p-6Y-EGFR mutants TAS Homo sapiens 456216 R-HSA-1226094 https://reactome.org/PathwayBrowser/#/R-HSA-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex TAS Homo sapiens 456216 R-HSA-1226095 https://reactome.org/PathwayBrowser/#/R-HSA-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex TAS Homo sapiens 456216 R-HSA-1236949 https://reactome.org/PathwayBrowser/#/R-HSA-1236949 Translocation of antigenic peptides back to phagosomes via TAP IEA Homo sapiens 456216 R-HSA-1247844 https://reactome.org/PathwayBrowser/#/R-HSA-1247844 Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants TAS Homo sapiens 456216 R-HSA-1247935 https://reactome.org/PathwayBrowser/#/R-HSA-1247935 OPLAH hydrolyses OPRO to L-Glu TAS Homo sapiens 456216 R-HSA-1247960 https://reactome.org/PathwayBrowser/#/R-HSA-1247960 Activation of p38 MAPK TAS Homo sapiens 456216 R-HSA-1248655 https://reactome.org/PathwayBrowser/#/R-HSA-1248655 Trans-autophosphorylation of EGFRvIII mutant dimers TAS Homo sapiens 456216 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 456216 R-HSA-1250195 https://reactome.org/PathwayBrowser/#/R-HSA-1250195 SHC1 phosphorylation by ERBB2 heterodimers TAS Homo sapiens 456216 R-HSA-1250315 https://reactome.org/PathwayBrowser/#/R-HSA-1250315 Trans-autophosphorylation of ERBB4 homodimers TAS Homo sapiens 456216 R-HSA-1250348 https://reactome.org/PathwayBrowser/#/R-HSA-1250348 Phosphorylation of SHC1 by ERBB4 homodimers TAS Homo sapiens 456216 R-HSA-1250370 https://reactome.org/PathwayBrowser/#/R-HSA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers TAS Homo sapiens 456216 R-HSA-1250462 https://reactome.org/PathwayBrowser/#/R-HSA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 TAS Homo sapiens 456216 R-HSA-1251922 https://reactome.org/PathwayBrowser/#/R-HSA-1251922 PLCG1 phosphorylation by p-EGFR:p-ERBB2 IEA Homo sapiens 456216 R-HSA-1295519 https://reactome.org/PathwayBrowser/#/R-HSA-1295519 IL7R is phosphorylated on Y499 IEA Homo sapiens 456216 R-HSA-1295540 https://reactome.org/PathwayBrowser/#/R-HSA-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 TAS Homo sapiens 456216 R-HSA-1295609 https://reactome.org/PathwayBrowser/#/R-HSA-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 TAS Homo sapiens 456216 R-HSA-1299475 https://reactome.org/PathwayBrowser/#/R-HSA-1299475 TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix IEA Homo sapiens 456216 R-HSA-1306957 https://reactome.org/PathwayBrowser/#/R-HSA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR TAS Homo sapiens 456216 R-HSA-1306979 https://reactome.org/PathwayBrowser/#/R-HSA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 TAS Homo sapiens 456216 R-HSA-1307963 https://reactome.org/PathwayBrowser/#/R-HSA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 TAS Homo sapiens 456216 R-HSA-1358791 https://reactome.org/PathwayBrowser/#/R-HSA-1358791 Phosphorylation of USP8 by P-AKT TAS Homo sapiens 456216 R-HSA-1362270 https://reactome.org/PathwayBrowser/#/R-HSA-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A TAS Homo sapiens 456216 R-HSA-1364043 https://reactome.org/PathwayBrowser/#/R-HSA-1364043 Tyrosine phosphorylation of PRLR IEA Homo sapiens 456216 R-HSA-1369028 https://reactome.org/PathwayBrowser/#/R-HSA-1369028 ABCAs mediate lipid efflux TAS Homo sapiens 456216 R-HSA-1369052 https://reactome.org/PathwayBrowser/#/R-HSA-1369052 ABCAs mediate lipid influx TAS Homo sapiens 456216 R-HSA-1369065 https://reactome.org/PathwayBrowser/#/R-HSA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix TAS Homo sapiens 456216 R-HSA-1369115 https://reactome.org/PathwayBrowser/#/R-HSA-1369115 SHP2 is phosphorylated IEA Homo sapiens 456216 R-HSA-1370505 https://reactome.org/PathwayBrowser/#/R-HSA-1370505 PRLR is phosphorylated at Ser-349 TAS Homo sapiens 456216 R-HSA-139908 https://reactome.org/PathwayBrowser/#/R-HSA-139908 Phosphorylation of DLC2 by MAPK8 TAS Homo sapiens 456216 R-HSA-139918 https://reactome.org/PathwayBrowser/#/R-HSA-139918 Phosphorylation of BIM by JNK TAS Homo sapiens 456216 R-HSA-1433418 https://reactome.org/PathwayBrowser/#/R-HSA-1433418 Phosphorylation of JAK2 TAS Homo sapiens 456216 R-HSA-1433454 https://reactome.org/PathwayBrowser/#/R-HSA-1433454 Phosphorylation of GAB2 by SFKs TAS Homo sapiens 456216 R-HSA-1433488 https://reactome.org/PathwayBrowser/#/R-HSA-1433488 Phosphorylation of SHP2 by SFKs TAS Homo sapiens 456216 R-HSA-1433506 https://reactome.org/PathwayBrowser/#/R-HSA-1433506 Phosphorylation of APS TAS Homo sapiens 456216 R-HSA-1433508 https://reactome.org/PathwayBrowser/#/R-HSA-1433508 PKC alpha interacts with and phosphorylates KIT TAS Homo sapiens 456216 R-HSA-1433514 https://reactome.org/PathwayBrowser/#/R-HSA-1433514 Synthesis of PIP3 from PIP2 by PI3K TAS Homo sapiens 456216 R-HSA-1433542 https://reactome.org/PathwayBrowser/#/R-HSA-1433542 Phosphorylation and activation of VAV1 TAS Homo sapiens 456216 R-HSA-1445144 https://reactome.org/PathwayBrowser/#/R-HSA-1445144 p-AKT1,p-AKT2 phosphorylates AS160 (TBC1D4) IEA Homo sapiens 456216 R-HSA-1449574 https://reactome.org/PathwayBrowser/#/R-HSA-1449574 SLC2A4 (GLUT4) vesicle fuses with the plasma membrane IEA Homo sapiens 456216 R-HSA-1449597 https://reactome.org/PathwayBrowser/#/R-HSA-1449597 p-AKT2 phosphorylates Myosin 5A IEA Homo sapiens 456216 R-HSA-1454699 https://reactome.org/PathwayBrowser/#/R-HSA-1454699 AMPK-alpha2 phosphorylates TBC1D1 IEA Homo sapiens 456216 R-HSA-1454916 https://reactome.org/PathwayBrowser/#/R-HSA-1454916 The ABCC family mediates organic anion transport TAS Homo sapiens 456216 R-HSA-1454928 https://reactome.org/PathwayBrowser/#/R-HSA-1454928 ABCG4 may mediate cholesterol efflux TAS Homo sapiens 456216 R-HSA-1458463 https://reactome.org/PathwayBrowser/#/R-HSA-1458463 p-AKT2 phosphorylates RGC2 IEA Homo sapiens 456216 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-1467466 https://reactome.org/PathwayBrowser/#/R-HSA-1467466 ABCA4 mediates atRAL transport TAS Homo sapiens 456216 R-HSA-1470009 https://reactome.org/PathwayBrowser/#/R-HSA-1470009 Phosphorylation of STATs TAS Homo sapiens 456216 R-HSA-1472121 https://reactome.org/PathwayBrowser/#/R-HSA-1472121 Phosphorylation of p-KIT on Y900 by Src kinases TAS Homo sapiens 456216 R-HSA-1475422 https://reactome.org/PathwayBrowser/#/R-HSA-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II TAS Homo sapiens 456216 R-HSA-1483004 https://reactome.org/PathwayBrowser/#/R-HSA-1483004 Cho is phosphorylated to PCho by CHK dimer TAS Homo sapiens 456216 R-HSA-1483222 https://reactome.org/PathwayBrowser/#/R-HSA-1483222 ETA is phosphorylated to PETA by CHK/ETNK TAS Homo sapiens 456216 R-HSA-1497853 https://reactome.org/PathwayBrowser/#/R-HSA-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II TAS Homo sapiens 456216 R-HSA-1524186 https://reactome.org/PathwayBrowser/#/R-HSA-1524186 Phosphorylation of PLCgamma by PDGFR TAS Homo sapiens 456216 R-HSA-1549526 https://reactome.org/PathwayBrowser/#/R-HSA-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor TAS Homo sapiens 456216 R-HSA-156673 https://reactome.org/PathwayBrowser/#/R-HSA-156673 Regulation of KIF23 (MKLP1) by phosphorylation TAS Homo sapiens 456216 R-HSA-156678 https://reactome.org/PathwayBrowser/#/R-HSA-156678 Activation of Cdc25C TAS Homo sapiens 456216 R-HSA-156682 https://reactome.org/PathwayBrowser/#/R-HSA-156682 PLK1 phosphorylates NUDC TAS Homo sapiens 456216 R-HSA-156699 https://reactome.org/PathwayBrowser/#/R-HSA-156699 Inactivation of Wee1 kinase TAS Homo sapiens 456216 R-HSA-156723 https://reactome.org/PathwayBrowser/#/R-HSA-156723 Regulation of KIF20A (MKL2) by phosphorylation TAS Homo sapiens 456216 R-HSA-156832 https://reactome.org/PathwayBrowser/#/R-HSA-156832 INF-gamma induced phosphorylation of L13a TAS Homo sapiens 456216 R-HSA-159101 https://reactome.org/PathwayBrowser/#/R-HSA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) TAS Homo sapiens 456216 R-HSA-1592233 https://reactome.org/PathwayBrowser/#/R-HSA-1592233 p38 MAPK phosphorylates PPARGC1A IEA Homo sapiens 456216 R-HSA-1592244 https://reactome.org/PathwayBrowser/#/R-HSA-1592244 AMPK phosphorylates PPARGC1A IEA Homo sapiens 456216 R-HSA-1606324 https://reactome.org/PathwayBrowser/#/R-HSA-1606324 Recruitment TBK1 to dsDNA:ZBP1 followed by its activation IEA Homo sapiens 456216 R-HSA-1606327 https://reactome.org/PathwayBrowser/#/R-HSA-1606327 Phosphorylation and release of IRF3 TAS Homo sapiens 456216 R-HSA-162363 https://reactome.org/PathwayBrowser/#/R-HSA-162363 p-T309,S474-AKT2:PIP3 phosphorylates PDE3B IEA Homo sapiens 456216 R-HSA-162657 https://reactome.org/PathwayBrowser/#/R-HSA-162657 Inactivation of Myt1 kinase TAS Homo sapiens 456216 R-HSA-163010 https://reactome.org/PathwayBrowser/#/R-HSA-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 TAS Homo sapiens 456216 R-HSA-163120 https://reactome.org/PathwayBrowser/#/R-HSA-163120 Disassociation of Telomerase RNP and the Chromosome End TAS Homo sapiens 456216 R-HSA-163215 https://reactome.org/PathwayBrowser/#/R-HSA-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane TAS Homo sapiens 456216 R-HSA-1632857 https://reactome.org/PathwayBrowser/#/R-HSA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex TAS Homo sapiens 456216 R-HSA-163416 https://reactome.org/PathwayBrowser/#/R-HSA-163416 hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP IEA Homo sapiens 456216 R-HSA-163418 https://reactome.org/PathwayBrowser/#/R-HSA-163418 perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP IEA Homo sapiens 456216 R-HSA-163672 https://reactome.org/PathwayBrowser/#/R-HSA-163672 Phosphorylation of ChREBP at Thr(653) by PKA IEA Homo sapiens 456216 R-HSA-163676 https://reactome.org/PathwayBrowser/#/R-HSA-163676 Phosphorylation of pChREBP (Thr 653) at Ser(196) by PKA IEA Homo sapiens 456216 R-HSA-163691 https://reactome.org/PathwayBrowser/#/R-HSA-163691 Phosphorylation of ChREBP at Serine 556 by AMPK IEA Homo sapiens 456216 R-HSA-163773 https://reactome.org/PathwayBrowser/#/R-HSA-163773 Phosphorylation of PF2K-Pase by PKA catalytic subunit IEA Homo sapiens 456216 R-HSA-1638803 https://reactome.org/PathwayBrowser/#/R-HSA-1638803 Phosphorylation of cohesin by PLK1 at centromeres TAS Homo sapiens 456216 R-HSA-1638845 https://reactome.org/PathwayBrowser/#/R-HSA-1638845 CERK phosphorylates CERA to form C1P TAS Homo sapiens 456216 R-HSA-164151 https://reactome.org/PathwayBrowser/#/R-HSA-164151 LKB1 phosphorylates the alpha subunit of AMPK heterotrimer IEA Homo sapiens 456216 R-HSA-164832 https://reactome.org/PathwayBrowser/#/R-HSA-164832 ATPase synthesizes ATP TAS Homo sapiens 456216 R-HSA-164840 https://reactome.org/PathwayBrowser/#/R-HSA-164840 ADP and Pi bind to ATPase TAS Homo sapiens 456216 R-HSA-165162 https://reactome.org/PathwayBrowser/#/R-HSA-165162 Phosphorylation of TSC2 by PKB TAS Homo sapiens 456216 R-HSA-165182 https://reactome.org/PathwayBrowser/#/R-HSA-165182 Phosphorylation of complexed TSC2 by PKB TAS Homo sapiens 456216 R-HSA-165692 https://reactome.org/PathwayBrowser/#/R-HSA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 TAS Homo sapiens 456216 R-HSA-165718 https://reactome.org/PathwayBrowser/#/R-HSA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) TAS Homo sapiens 456216 R-HSA-165726 https://reactome.org/PathwayBrowser/#/R-HSA-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 TAS Homo sapiens 456216 R-HSA-165758 https://reactome.org/PathwayBrowser/#/R-HSA-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 TAS Homo sapiens 456216 R-HSA-165766 https://reactome.org/PathwayBrowser/#/R-HSA-165766 Phosphorylation and activation of eIF4G by activated S6K1 TAS Homo sapiens 456216 R-HSA-165777 https://reactome.org/PathwayBrowser/#/R-HSA-165777 Phosphorylation and activation of eIF4B by activated S6K1 TAS Homo sapiens 456216 R-HSA-166119 https://reactome.org/PathwayBrowser/#/R-HSA-166119 First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal TAS Homo sapiens 456216 R-HSA-166245 https://reactome.org/PathwayBrowser/#/R-HSA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex TAS Homo sapiens 456216 R-HSA-166284 https://reactome.org/PathwayBrowser/#/R-HSA-166284 Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP TAS Homo sapiens 456216 R-HSA-166286 https://reactome.org/PathwayBrowser/#/R-HSA-166286 Multiple IRAK1 autophosphorylation steps TAS Homo sapiens 456216 R-HSA-166544 https://reactome.org/PathwayBrowser/#/R-HSA-166544 TrkA receptor autophosphorylates IEA Homo sapiens 456216 R-HSA-167019 https://reactome.org/PathwayBrowser/#/R-HSA-167019 SHC, complexed with TrkA, is tyrosine-phosphorylated IEA Homo sapiens 456216 R-HSA-167084 https://reactome.org/PathwayBrowser/#/R-HSA-167084 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Homo sapiens 456216 R-HSA-167097 https://reactome.org/PathwayBrowser/#/R-HSA-167097 HIV Promoter Opening: First Transition IEA Homo sapiens 456216 R-HSA-167098 https://reactome.org/PathwayBrowser/#/R-HSA-167098 Phosphorylation (Ser5) of RNA pol II CTD IEA Homo sapiens 456216 R-HSA-1671691 https://reactome.org/PathwayBrowser/#/R-HSA-1671691 PRLR-bound STAT5 is phosphorylated IEA Homo sapiens 456216 R-HSA-167191 https://reactome.org/PathwayBrowser/#/R-HSA-167191 Hyperphosphorylation (Ser2) of RNA Pol II CTD by the P-TEFb(Cyclin T1:Cdk9) complex IEA Homo sapiens 456216 R-HSA-1675773 https://reactome.org/PathwayBrowser/#/R-HSA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane TAS Homo sapiens 456216 R-HSA-1675776 https://reactome.org/PathwayBrowser/#/R-HSA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane TAS Homo sapiens 456216 R-HSA-1675780 https://reactome.org/PathwayBrowser/#/R-HSA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane TAS Homo sapiens 456216 R-HSA-1675810 https://reactome.org/PathwayBrowser/#/R-HSA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane TAS Homo sapiens 456216 R-HSA-1675813 https://reactome.org/PathwayBrowser/#/R-HSA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane TAS Homo sapiens 456216 R-HSA-1675866 https://reactome.org/PathwayBrowser/#/R-HSA-1675866 PI is phosphorylated to PI5P by PIKFYVE at the late endosome membrane IEA Homo sapiens 456216 R-HSA-1675883 https://reactome.org/PathwayBrowser/#/R-HSA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane TAS Homo sapiens 456216 R-HSA-1675910 https://reactome.org/PathwayBrowser/#/R-HSA-1675910 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the late endosome membrane IEA Homo sapiens 456216 R-HSA-1675921 https://reactome.org/PathwayBrowser/#/R-HSA-1675921 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the Golgi membrane IEA Homo sapiens 456216 R-HSA-1675928 https://reactome.org/PathwayBrowser/#/R-HSA-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane TAS Homo sapiens 456216 R-HSA-1675939 https://reactome.org/PathwayBrowser/#/R-HSA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane TAS Homo sapiens 456216 R-HSA-1675961 https://reactome.org/PathwayBrowser/#/R-HSA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane TAS Homo sapiens 456216 R-HSA-1675974 https://reactome.org/PathwayBrowser/#/R-HSA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane TAS Homo sapiens 456216 R-HSA-1676024 https://reactome.org/PathwayBrowser/#/R-HSA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane TAS Homo sapiens 456216 R-HSA-1676048 https://reactome.org/PathwayBrowser/#/R-HSA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane TAS Homo sapiens 456216 R-HSA-1676082 https://reactome.org/PathwayBrowser/#/R-HSA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane TAS Homo sapiens 456216 R-HSA-1676109 https://reactome.org/PathwayBrowser/#/R-HSA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane TAS Homo sapiens 456216 R-HSA-1676134 https://reactome.org/PathwayBrowser/#/R-HSA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane TAS Homo sapiens 456216 R-HSA-1676145 https://reactome.org/PathwayBrowser/#/R-HSA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane TAS Homo sapiens 456216 R-HSA-1676168 https://reactome.org/PathwayBrowser/#/R-HSA-1676168 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane IEA Homo sapiens 456216 R-HSA-1676185 https://reactome.org/PathwayBrowser/#/R-HSA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane TAS Homo sapiens 456216 R-HSA-1676206 https://reactome.org/PathwayBrowser/#/R-HSA-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane TAS Homo sapiens 456216 R-HSA-167683 https://reactome.org/PathwayBrowser/#/R-HSA-167683 TrkA phosphorylates PLCG1 IEA Homo sapiens 456216 R-HSA-1678944 https://reactome.org/PathwayBrowser/#/R-HSA-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex TAS Homo sapiens 456216 R-HSA-168053 https://reactome.org/PathwayBrowser/#/R-HSA-168053 Phosphorylated MAPKs phosphorylate ATF-2 TAS Homo sapiens 456216 R-HSA-168136 https://reactome.org/PathwayBrowser/#/R-HSA-168136 Activated JNKs phosphorylate c-JUN TAS Homo sapiens 456216 R-HSA-168140 https://reactome.org/PathwayBrowser/#/R-HSA-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor TAS Homo sapiens 456216 R-HSA-168162 https://reactome.org/PathwayBrowser/#/R-HSA-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 TAS Homo sapiens 456216 R-HSA-168184 https://reactome.org/PathwayBrowser/#/R-HSA-168184 Activated TAK1 mediates phosphorylation of the IKK Complex TAS Homo sapiens 456216 R-HSA-168910 https://reactome.org/PathwayBrowser/#/R-HSA-168910 RIP1 facilitates IKK complex phosphorylation TAS Homo sapiens 456216 R-HSA-169905 https://reactome.org/PathwayBrowser/#/R-HSA-169905 ARMS is phosphorylated by active TrkA receptor TAS Homo sapiens 456216 R-HSA-170026 https://reactome.org/PathwayBrowser/#/R-HSA-170026 Protons are translocated from the intermembrane space to the matrix TAS Homo sapiens 456216 R-HSA-170055 https://reactome.org/PathwayBrowser/#/R-HSA-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes TAS Homo sapiens 456216 R-HSA-170070 https://reactome.org/PathwayBrowser/#/R-HSA-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes TAS Homo sapiens 456216 R-HSA-170076 https://reactome.org/PathwayBrowser/#/R-HSA-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes TAS Homo sapiens 456216 R-HSA-170087 https://reactome.org/PathwayBrowser/#/R-HSA-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes TAS Homo sapiens 456216 R-HSA-170116 https://reactome.org/PathwayBrowser/#/R-HSA-170116 Myt-1 mediated phosphorylation of Cyclin A:Cdc2 IEA Homo sapiens 456216 R-HSA-170126 https://reactome.org/PathwayBrowser/#/R-HSA-170126 Phosphorylation of Cyclin B1 in the CRS domain TAS Homo sapiens 456216 R-HSA-170156 https://reactome.org/PathwayBrowser/#/R-HSA-170156 Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes IEA Homo sapiens 456216 R-HSA-170704 https://reactome.org/PathwayBrowser/#/R-HSA-170704 Phosphorylation of DSIF by the P-TEFb(Cyclin T1:Cdk9) complex TAS Homo sapiens 456216 R-HSA-170706 https://reactome.org/PathwayBrowser/#/R-HSA-170706 Phosphorylation of NEFL by the P-TEFb(Cyclin T1:Cdk9) complex TAS Homo sapiens 456216 R-HSA-170843 https://reactome.org/PathwayBrowser/#/R-HSA-170843 TGFBR2 phosphorylates TGFBR1 TAS Homo sapiens 456216 R-HSA-170868 https://reactome.org/PathwayBrowser/#/R-HSA-170868 Activated type I receptor phosphorylates SMAD2/3 directly TAS Homo sapiens 456216 R-HSA-170977 https://reactome.org/PathwayBrowser/#/R-HSA-170977 FRS2 is phosphorylated by active TrkA receptor TAS Homo sapiens 456216 R-HSA-170991 https://reactome.org/PathwayBrowser/#/R-HSA-170991 SRC-1 autophosphorylates IEA Homo sapiens 456216 R-HSA-171011 https://reactome.org/PathwayBrowser/#/R-HSA-171011 Binding and activation of MAP Kinase IEA Homo sapiens 456216 R-HSA-174079 https://reactome.org/PathwayBrowser/#/R-HSA-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 TAS Homo sapiens 456216 R-HSA-174122 https://reactome.org/PathwayBrowser/#/R-HSA-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 TAS Homo sapiens 456216 R-HSA-174164 https://reactome.org/PathwayBrowser/#/R-HSA-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 TAS Homo sapiens 456216 R-HSA-174174 https://reactome.org/PathwayBrowser/#/R-HSA-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 TAS Homo sapiens 456216 R-HSA-174251 https://reactome.org/PathwayBrowser/#/R-HSA-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 TAS Homo sapiens 456216 R-HSA-174367 https://reactome.org/PathwayBrowser/#/R-HSA-174367 GCL ligates L-Glu to L-Cys TAS Homo sapiens 456216 R-HSA-174389 https://reactome.org/PathwayBrowser/#/R-HSA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS TAS Homo sapiens 456216 R-HSA-174394 https://reactome.org/PathwayBrowser/#/R-HSA-174394 GSS:Mg2+ dimer synthesizes GSH TAS Homo sapiens 456216 R-HSA-174438 https://reactome.org/PathwayBrowser/#/R-HSA-174438 Formation of the Flap Intermediate on the C-strand TAS Homo sapiens 456216 R-HSA-174439 https://reactome.org/PathwayBrowser/#/R-HSA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere TAS Homo sapiens 456216 R-HSA-176116 https://reactome.org/PathwayBrowser/#/R-HSA-176116 Recruitment and activation of Chk1 TAS Homo sapiens 456216 R-HSA-176298 https://reactome.org/PathwayBrowser/#/R-HSA-176298 Activation of claspin TAS Homo sapiens 456216 R-HSA-177275 https://reactome.org/PathwayBrowser/#/R-HSA-177275 PKA phosphorylates DARPP-32 on Thr34 TAS Homo sapiens 456216 R-HSA-177284 https://reactome.org/PathwayBrowser/#/R-HSA-177284 PKA phosphorylates PDE4B TAS Homo sapiens 456216 R-HSA-177692 https://reactome.org/PathwayBrowser/#/R-HSA-177692 Activation of recruited TAK1 within the activated TLR3 complex TAS Homo sapiens 456216 R-HSA-177930 https://reactome.org/PathwayBrowser/#/R-HSA-177930 GAB1 phosphorylation by EGFR kinase TAS Homo sapiens 456216 R-HSA-177933 https://reactome.org/PathwayBrowser/#/R-HSA-177933 SHC1 phosphorylation by phosphorylated EGFR TAS Homo sapiens 456216 R-HSA-177934 https://reactome.org/PathwayBrowser/#/R-HSA-177934 EGFR autophosphorylation TAS Homo sapiens 456216 R-HSA-177937 https://reactome.org/PathwayBrowser/#/R-HSA-177937 Phosphorylation of EGFR by SRC kinase TAS Homo sapiens 456216 R-HSA-177939 https://reactome.org/PathwayBrowser/#/R-HSA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) TAS Homo sapiens 456216 R-HSA-182969 https://reactome.org/PathwayBrowser/#/R-HSA-182969 Phosphorylation of CBL (EGFR:CBL) TAS Homo sapiens 456216 R-HSA-183058 https://reactome.org/PathwayBrowser/#/R-HSA-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) TAS Homo sapiens 456216 R-HSA-1839065 https://reactome.org/PathwayBrowser/#/R-HSA-1839065 Phosphorylation of cytosolic FGFR1 fusion dimers TAS Homo sapiens 456216 R-HSA-1839067 https://reactome.org/PathwayBrowser/#/R-HSA-1839067 Phosphorylation of BCR moiety of BCR-FGFR1 TAS Homo sapiens 456216 R-HSA-1839091 https://reactome.org/PathwayBrowser/#/R-HSA-1839091 Cytosolic FGFR1 fusion protein-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-1839098 https://reactome.org/PathwayBrowser/#/R-HSA-1839098 Activated FGFR1 mutants and fusions phosphorylate PLCG1 TAS Homo sapiens 456216 R-HSA-1839107 https://reactome.org/PathwayBrowser/#/R-HSA-1839107 BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3. TAS Homo sapiens 456216 R-HSA-1839110 https://reactome.org/PathwayBrowser/#/R-HSA-1839110 p-BCR-p-FGFR1 phosphorylates GAB2 TAS Homo sapiens 456216 R-HSA-1839112 https://reactome.org/PathwayBrowser/#/R-HSA-1839112 Phosphorylation of STAT5 by cytosolic FGFR1 fusions TAS Homo sapiens 456216 R-HSA-1855153 https://reactome.org/PathwayBrowser/#/R-HSA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol TAS Homo sapiens 456216 R-HSA-1855157 https://reactome.org/PathwayBrowser/#/R-HSA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus TAS Homo sapiens 456216 R-HSA-1855158 https://reactome.org/PathwayBrowser/#/R-HSA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol TAS Homo sapiens 456216 R-HSA-1855162 https://reactome.org/PathwayBrowser/#/R-HSA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol TAS Homo sapiens 456216 R-HSA-1855169 https://reactome.org/PathwayBrowser/#/R-HSA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 456216 R-HSA-1855172 https://reactome.org/PathwayBrowser/#/R-HSA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol TAS Homo sapiens 456216 R-HSA-1855176 https://reactome.org/PathwayBrowser/#/R-HSA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus TAS Homo sapiens 456216 R-HSA-1855179 https://reactome.org/PathwayBrowser/#/R-HSA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol TAS Homo sapiens 456216 R-HSA-1855181 https://reactome.org/PathwayBrowser/#/R-HSA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus TAS Homo sapiens 456216 R-HSA-1855182 https://reactome.org/PathwayBrowser/#/R-HSA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol TAS Homo sapiens 456216 R-HSA-1855185 https://reactome.org/PathwayBrowser/#/R-HSA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 456216 R-HSA-1855193 https://reactome.org/PathwayBrowser/#/R-HSA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol TAS Homo sapiens 456216 R-HSA-1855194 https://reactome.org/PathwayBrowser/#/R-HSA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol TAS Homo sapiens 456216 R-HSA-1855197 https://reactome.org/PathwayBrowser/#/R-HSA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 456216 R-HSA-1855206 https://reactome.org/PathwayBrowser/#/R-HSA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 456216 R-HSA-1855207 https://reactome.org/PathwayBrowser/#/R-HSA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus TAS Homo sapiens 456216 R-HSA-1855216 https://reactome.org/PathwayBrowser/#/R-HSA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol TAS Homo sapiens 456216 R-HSA-1855223 https://reactome.org/PathwayBrowser/#/R-HSA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol TAS Homo sapiens 456216 R-HSA-1855224 https://reactome.org/PathwayBrowser/#/R-HSA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus TAS Homo sapiens 456216 R-HSA-1855227 https://reactome.org/PathwayBrowser/#/R-HSA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol TAS Homo sapiens 456216 R-HSA-1855228 https://reactome.org/PathwayBrowser/#/R-HSA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 456216 R-HSA-1855230 https://reactome.org/PathwayBrowser/#/R-HSA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus TAS Homo sapiens 456216 R-HSA-1855233 https://reactome.org/PathwayBrowser/#/R-HSA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus TAS Homo sapiens 456216 R-HSA-1861595 https://reactome.org/PathwayBrowser/#/R-HSA-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner TAS Homo sapiens 456216 R-HSA-186786 https://reactome.org/PathwayBrowser/#/R-HSA-186786 Autophosphorylation of PDGF beta receptors TAS Homo sapiens 456216 R-HSA-186800 https://reactome.org/PathwayBrowser/#/R-HSA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-187520 https://reactome.org/PathwayBrowser/#/R-HSA-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 TAS Homo sapiens 456216 R-HSA-187688 https://reactome.org/PathwayBrowser/#/R-HSA-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 TAS Homo sapiens 456216 R-HSA-187916 https://reactome.org/PathwayBrowser/#/R-HSA-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 TAS Homo sapiens 456216 R-HSA-187948 https://reactome.org/PathwayBrowser/#/R-HSA-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 TAS Homo sapiens 456216 R-HSA-187949 https://reactome.org/PathwayBrowser/#/R-HSA-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 TAS Homo sapiens 456216 R-HSA-187959 https://reactome.org/PathwayBrowser/#/R-HSA-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) TAS Homo sapiens 456216 R-HSA-188350 https://reactome.org/PathwayBrowser/#/R-HSA-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 TAS Homo sapiens 456216 R-HSA-188390 https://reactome.org/PathwayBrowser/#/R-HSA-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 TAS Homo sapiens 456216 R-HSA-1888198 https://reactome.org/PathwayBrowser/#/R-HSA-1888198 FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 TAS Homo sapiens 456216 R-HSA-190326 https://reactome.org/PathwayBrowser/#/R-HSA-190326 Autocatalytic phosphorylation of FGFR4 TAS Homo sapiens 456216 R-HSA-190385 https://reactome.org/PathwayBrowser/#/R-HSA-190385 Autocatalytic phosphorylation of FGFR3b TAS Homo sapiens 456216 R-HSA-190388 https://reactome.org/PathwayBrowser/#/R-HSA-190388 Autocatalytic phosphorylation of FGFR3c TAS Homo sapiens 456216 R-HSA-190408 https://reactome.org/PathwayBrowser/#/R-HSA-190408 Autocatalytic phosphorylation of FGFR2b TAS Homo sapiens 456216 R-HSA-190413 https://reactome.org/PathwayBrowser/#/R-HSA-190413 Autocatalytic phosphorylation of FGFR2c TAS Homo sapiens 456216 R-HSA-190427 https://reactome.org/PathwayBrowser/#/R-HSA-190427 Autocatalytic phosphorylation of FGFR1b TAS Homo sapiens 456216 R-HSA-190429 https://reactome.org/PathwayBrowser/#/R-HSA-190429 Autocatalytic phosphorylation of FGFR1c TAS Homo sapiens 456216 R-HSA-191062 https://reactome.org/PathwayBrowser/#/R-HSA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c TAS Homo sapiens 456216 R-HSA-1912391 https://reactome.org/PathwayBrowser/#/R-HSA-1912391 NICD1 is phosphorylated by CDK8 IEA Homo sapiens 456216 R-HSA-191380 https://reactome.org/PathwayBrowser/#/R-HSA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate TAS Homo sapiens 456216 R-HSA-191414 https://reactome.org/PathwayBrowser/#/R-HSA-191414 MVD decarboxylates MVA5PP to IPPP TAS Homo sapiens 456216 R-HSA-191422 https://reactome.org/PathwayBrowser/#/R-HSA-191422 Mevalonate-5-phosphate is further phosphorylated. TAS Homo sapiens 456216 R-HSA-191636 https://reactome.org/PathwayBrowser/#/R-HSA-191636 Phosphorylation of Cx43 by c-src TAS Homo sapiens 456216 R-HSA-193362 https://reactome.org/PathwayBrowser/#/R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-193647 https://reactome.org/PathwayBrowser/#/R-HSA-193647 IRAK is activated IEA Homo sapiens 456216 R-HSA-193703 https://reactome.org/PathwayBrowser/#/R-HSA-193703 IKKbeta is activated TAS Homo sapiens 456216 R-HSA-193705 https://reactome.org/PathwayBrowser/#/R-HSA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate TAS Homo sapiens 456216 R-HSA-194153 https://reactome.org/PathwayBrowser/#/R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-195275 https://reactome.org/PathwayBrowser/#/R-HSA-195275 Phosphorylation of APC component of the destruction complex TAS Homo sapiens 456216 R-HSA-195283 https://reactome.org/PathwayBrowser/#/R-HSA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 TAS Homo sapiens 456216 R-HSA-195287 https://reactome.org/PathwayBrowser/#/R-HSA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 TAS Homo sapiens 456216 R-HSA-195300 https://reactome.org/PathwayBrowser/#/R-HSA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 TAS Homo sapiens 456216 R-HSA-195318 https://reactome.org/PathwayBrowser/#/R-HSA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha TAS Homo sapiens 456216 R-HSA-1963581 https://reactome.org/PathwayBrowser/#/R-HSA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers TAS Homo sapiens 456216 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 456216 R-HSA-1963586 https://reactome.org/PathwayBrowser/#/R-HSA-1963586 SRC family kinases phosphorylate ERBB2 TAS Homo sapiens 456216 R-HSA-196773 https://reactome.org/PathwayBrowser/#/R-HSA-196773 COASY phosphorylates DP-CoA TAS Homo sapiens 456216 R-HSA-196857 https://reactome.org/PathwayBrowser/#/R-HSA-196857 PANK2 phosphorylates PanK TAS Homo sapiens 456216 R-HSA-196964 https://reactome.org/PathwayBrowser/#/R-HSA-196964 RFK:Mg2+ phosphorylates RIB TAS Homo sapiens 456216 R-HSA-197198 https://reactome.org/PathwayBrowser/#/R-HSA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ TAS Homo sapiens 456216 R-HSA-197958 https://reactome.org/PathwayBrowser/#/R-HSA-197958 FPGS-2 transforms THF to THFPG TAS Homo sapiens 456216 R-HSA-1982066 https://reactome.org/PathwayBrowser/#/R-HSA-1982066 Ligand-independent phosphorylation of overexpressed FGFR1 TAS Homo sapiens 456216 R-HSA-198266 https://reactome.org/PathwayBrowser/#/R-HSA-198266 PI3K produces PIP3 and other phosphatidyl inositides TAS Homo sapiens 456216 R-HSA-198270 https://reactome.org/PathwayBrowser/#/R-HSA-198270 PDPK1 phosphorylates AKT at T308 TAS Homo sapiens 456216 R-HSA-198295 https://reactome.org/PathwayBrowser/#/R-HSA-198295 TRKA phosphorylates IRS IEA Homo sapiens 456216 R-HSA-198314 https://reactome.org/PathwayBrowser/#/R-HSA-198314 DAG stimulates protein kinase C-delta TAS Homo sapiens 456216 R-HSA-198347 https://reactome.org/PathwayBrowser/#/R-HSA-198347 AKT phosphorylates BAD IEA Homo sapiens 456216 R-HSA-198371 https://reactome.org/PathwayBrowser/#/R-HSA-198371 AKT phosphorylates GSK3 IEA Homo sapiens 456216 R-HSA-198599 https://reactome.org/PathwayBrowser/#/R-HSA-198599 AKT phosphorylates MDM2 TAS Homo sapiens 456216 R-HSA-198609 https://reactome.org/PathwayBrowser/#/R-HSA-198609 AKT phosphorylates TSC2, inhibiting it TAS Homo sapiens 456216 R-HSA-198611 https://reactome.org/PathwayBrowser/#/R-HSA-198611 AKT phosphorylates IKKalpha TAS Homo sapiens 456216 R-HSA-198613 https://reactome.org/PathwayBrowser/#/R-HSA-198613 AKT phosphorylates p21Cip1 and p27Kip1 TAS Homo sapiens 456216 R-HSA-198621 https://reactome.org/PathwayBrowser/#/R-HSA-198621 AKT phosphorylates caspase-9 TAS Homo sapiens 456216 R-HSA-198640 https://reactome.org/PathwayBrowser/#/R-HSA-198640 TORC2 (mTOR) phosphorylates AKT at S473 TAS Homo sapiens 456216 R-HSA-198669 https://reactome.org/PathwayBrowser/#/R-HSA-198669 p38MAPK phosphorylates MSK1 TAS Homo sapiens 456216 R-HSA-198731 https://reactome.org/PathwayBrowser/#/R-HSA-198731 ERK1/2 activates ELK1 IEA Homo sapiens 456216 R-HSA-198732 https://reactome.org/PathwayBrowser/#/R-HSA-198732 STAT3 activation IEA Homo sapiens 456216 R-HSA-198733 https://reactome.org/PathwayBrowser/#/R-HSA-198733 ERK5 is activated IEA Homo sapiens 456216 R-HSA-198746 https://reactome.org/PathwayBrowser/#/R-HSA-198746 ERK1/2/5 activate RSK1/2/3 TAS Homo sapiens 456216 R-HSA-198756 https://reactome.org/PathwayBrowser/#/R-HSA-198756 ERK1/2 phosphorylates MSK1 TAS Homo sapiens 456216 R-HSA-199203 https://reactome.org/PathwayBrowser/#/R-HSA-199203 PANK1/3 phosphorylate PanK TAS Homo sapiens 456216 R-HSA-199298 https://reactome.org/PathwayBrowser/#/R-HSA-199298 AKT phosphorylates CREB1 TAS Homo sapiens 456216 R-HSA-199299 https://reactome.org/PathwayBrowser/#/R-HSA-199299 AKT phosphorylates FOXO transcription factors TAS Homo sapiens 456216 R-HSA-199839 https://reactome.org/PathwayBrowser/#/R-HSA-199839 AKT can phosphorylate RSK TAS Homo sapiens 456216 R-HSA-199863 https://reactome.org/PathwayBrowser/#/R-HSA-199863 AKT can phosphorylate NR4A1 (NUR77) TAS Homo sapiens 456216 R-HSA-199895 https://reactome.org/PathwayBrowser/#/R-HSA-199895 RSK1/2/3 phosphorylates CREB at Serine 119 TAS Homo sapiens 456216 R-HSA-199910 https://reactome.org/PathwayBrowser/#/R-HSA-199910 MSK1 activates ATF1 TAS Homo sapiens 456216 R-HSA-199917 https://reactome.org/PathwayBrowser/#/R-HSA-199917 MAPKAPK2 phosphorylates CREB at Serine 133 TAS Homo sapiens 456216 R-HSA-199929 https://reactome.org/PathwayBrowser/#/R-HSA-199929 ERK5 activates the transcription factor MEF2 IEA Homo sapiens 456216 R-HSA-199935 https://reactome.org/PathwayBrowser/#/R-HSA-199935 MSK1 activates CREB TAS Homo sapiens 456216 R-HSA-200143 https://reactome.org/PathwayBrowser/#/R-HSA-200143 AKT phosphorylates AKT1S1 (PRAS40) TAS Homo sapiens 456216 R-HSA-200318 https://reactome.org/PathwayBrowser/#/R-HSA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] TAS Homo sapiens 456216 R-HSA-200326 https://reactome.org/PathwayBrowser/#/R-HSA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] TAS Homo sapiens 456216 R-HSA-200421 https://reactome.org/PathwayBrowser/#/R-HSA-200421 Activation of cytosolic AMPK by phosphorylation TAS Homo sapiens 456216 R-HSA-200423 https://reactome.org/PathwayBrowser/#/R-HSA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis TAS Homo sapiens 456216 R-HSA-200555 https://reactome.org/PathwayBrowser/#/R-HSA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate TAS Homo sapiens 456216 R-HSA-200681 https://reactome.org/PathwayBrowser/#/R-HSA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG TAS Homo sapiens 456216 R-HSA-200682 https://reactome.org/PathwayBrowser/#/R-HSA-200682 Mitochondrial FPGS-1 transforms THF to THFPG TAS Homo sapiens 456216 R-HSA-200711 https://reactome.org/PathwayBrowser/#/R-HSA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG TAS Homo sapiens 456216 R-HSA-2012073 https://reactome.org/PathwayBrowser/#/R-HSA-2012073 Autocatalytic phosphorylation of FGFR3c P250R mutant TAS Homo sapiens 456216 R-HSA-2012082 https://reactome.org/PathwayBrowser/#/R-HSA-2012082 Autocatalytic phosphorylation of FGFR3 cysteine mutants TAS Homo sapiens 456216 R-HSA-2012087 https://reactome.org/PathwayBrowser/#/R-HSA-2012087 Autocatalytic phosphorylation of FGFR4 Y367C mutant TAS Homo sapiens 456216 R-HSA-201443 https://reactome.org/PathwayBrowser/#/R-HSA-201443 Type II receptor phosphorylates type I receptor TAS Homo sapiens 456216 R-HSA-201476 https://reactome.org/PathwayBrowser/#/R-HSA-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly TAS Homo sapiens 456216 R-HSA-201510 https://reactome.org/PathwayBrowser/#/R-HSA-201510 PI3K synthesizes PIP3 downstream of ALK TAS Homo sapiens 456216 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 456216 R-HSA-201677 https://reactome.org/PathwayBrowser/#/R-HSA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta TAS Homo sapiens 456216 R-HSA-201691 https://reactome.org/PathwayBrowser/#/R-HSA-201691 Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI IEA Homo sapiens 456216 R-HSA-201717 https://reactome.org/PathwayBrowser/#/R-HSA-201717 CSNK2-mediated phosphorylation of DVL TAS Homo sapiens 456216 R-HSA-202111 https://reactome.org/PathwayBrowser/#/R-HSA-202111 AKT1 phosphorylates eNOS TAS Homo sapiens 456216 R-HSA-202165 https://reactome.org/PathwayBrowser/#/R-HSA-202165 Phosphorylation of ITAM motifs in CD3 complexes TAS Homo sapiens 456216 R-HSA-202168 https://reactome.org/PathwayBrowser/#/R-HSA-202168 Phosphorylation of ZAP-70 by Lck TAS Homo sapiens 456216 R-HSA-202174 https://reactome.org/PathwayBrowser/#/R-HSA-202174 Activation of ZAP-70 TAS Homo sapiens 456216 R-HSA-202216 https://reactome.org/PathwayBrowser/#/R-HSA-202216 Phosphorylation of SLP-76 TAS Homo sapiens 456216 R-HSA-202222 https://reactome.org/PathwayBrowser/#/R-HSA-202222 Phosphorylation of PKC theta TAS Homo sapiens 456216 R-HSA-202233 https://reactome.org/PathwayBrowser/#/R-HSA-202233 Inactivation of Lck by Csk TAS Homo sapiens 456216 R-HSA-202245 https://reactome.org/PathwayBrowser/#/R-HSA-202245 Phosphorylation of TBSMs in LAT TAS Homo sapiens 456216 R-HSA-202248 https://reactome.org/PathwayBrowser/#/R-HSA-202248 Phosphorylation of PLC-gamma1 TAS Homo sapiens 456216 R-HSA-202291 https://reactome.org/PathwayBrowser/#/R-HSA-202291 Activation of Lck TAS Homo sapiens 456216 R-HSA-202307 https://reactome.org/PathwayBrowser/#/R-HSA-202307 Change of PKC theta conformation TAS Homo sapiens 456216 R-HSA-2023455 https://reactome.org/PathwayBrowser/#/R-HSA-2023455 Autocatalytic phosphorylation of FGFR1c P252X mutant dimers TAS Homo sapiens 456216 R-HSA-2023460 https://reactome.org/PathwayBrowser/#/R-HSA-2023460 Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity TAS Homo sapiens 456216 R-HSA-202365 https://reactome.org/PathwayBrowser/#/R-HSA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-202437 https://reactome.org/PathwayBrowser/#/R-HSA-202437 Phosphorylation of CARMA1 TAS Homo sapiens 456216 R-HSA-202459 https://reactome.org/PathwayBrowser/#/R-HSA-202459 Phosphorylation of Bcl10 TAS Homo sapiens 456216 R-HSA-202500 https://reactome.org/PathwayBrowser/#/R-HSA-202500 Activation of IKK complex TAS Homo sapiens 456216 R-HSA-202510 https://reactome.org/PathwayBrowser/#/R-HSA-202510 Activation of TAK1-TAB2 complex TAS Homo sapiens 456216 R-HSA-202541 https://reactome.org/PathwayBrowser/#/R-HSA-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB TAS Homo sapiens 456216 R-HSA-2028284 https://reactome.org/PathwayBrowser/#/R-HSA-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 TAS Homo sapiens 456216 R-HSA-2028555 https://reactome.org/PathwayBrowser/#/R-HSA-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) TAS Homo sapiens 456216 R-HSA-2028583 https://reactome.org/PathwayBrowser/#/R-HSA-2028583 Phosphorylation of YAP by LATS2 TAS Homo sapiens 456216 R-HSA-2028589 https://reactome.org/PathwayBrowser/#/R-HSA-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) TAS Homo sapiens 456216 R-HSA-2028591 https://reactome.org/PathwayBrowser/#/R-HSA-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 TAS Homo sapiens 456216 R-HSA-2028598 https://reactome.org/PathwayBrowser/#/R-HSA-2028598 Phosphorylation of YAP by LATS1 TAS Homo sapiens 456216 R-HSA-2028629 https://reactome.org/PathwayBrowser/#/R-HSA-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) TAS Homo sapiens 456216 R-HSA-2028635 https://reactome.org/PathwayBrowser/#/R-HSA-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) TAS Homo sapiens 456216 R-HSA-2028661 https://reactome.org/PathwayBrowser/#/R-HSA-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 TAS Homo sapiens 456216 R-HSA-2028670 https://reactome.org/PathwayBrowser/#/R-HSA-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N TAS Homo sapiens 456216 R-HSA-2028673 https://reactome.org/PathwayBrowser/#/R-HSA-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N TAS Homo sapiens 456216 R-HSA-2028675 https://reactome.org/PathwayBrowser/#/R-HSA-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N TAS Homo sapiens 456216 R-HSA-2028679 https://reactome.org/PathwayBrowser/#/R-HSA-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N TAS Homo sapiens 456216 R-HSA-2029268 https://reactome.org/PathwayBrowser/#/R-HSA-2029268 Phosphorylation and activation of PLCG TAS Homo sapiens 456216 R-HSA-2029271 https://reactome.org/PathwayBrowser/#/R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-2029449 https://reactome.org/PathwayBrowser/#/R-HSA-2029449 Phosphorylation of SYK by Src kinases IEA Homo sapiens 456216 R-HSA-2029453 https://reactome.org/PathwayBrowser/#/R-HSA-2029453 Phosphorylation of VAV TAS Homo sapiens 456216 R-HSA-2029454 https://reactome.org/PathwayBrowser/#/R-HSA-2029454 Autophosphorylation of PAK1 TAS Homo sapiens 456216 R-HSA-2029459 https://reactome.org/PathwayBrowser/#/R-HSA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts TAS Homo sapiens 456216 R-HSA-2029460 https://reactome.org/PathwayBrowser/#/R-HSA-2029460 PAK1 phosphorylates LIMK1 TAS Homo sapiens 456216 R-HSA-2029469 https://reactome.org/PathwayBrowser/#/R-HSA-2029469 p-ERK phosphorylates WAVEs and ABI TAS Homo sapiens 456216 R-HSA-2029473 https://reactome.org/PathwayBrowser/#/R-HSA-2029473 Branching and elongation of mother and daughter filaments TAS Homo sapiens 456216 R-HSA-2029476 https://reactome.org/PathwayBrowser/#/R-HSA-2029476 Role of myosins in phagosome formation TAS Homo sapiens 456216 R-HSA-2029984 https://reactome.org/PathwayBrowser/#/R-HSA-2029984 Autocatalytic phosphorylation of FGFR2 ligand-independent mutants TAS Homo sapiens 456216 R-HSA-2029989 https://reactome.org/PathwayBrowser/#/R-HSA-2029989 Autocatalytic phosphorylation of overexpressed FGFR2 variants TAS Homo sapiens 456216 R-HSA-2033485 https://reactome.org/PathwayBrowser/#/R-HSA-2033485 Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity TAS Homo sapiens 456216 R-HSA-2033486 https://reactome.org/PathwayBrowser/#/R-HSA-2033486 Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding TAS Homo sapiens 456216 R-HSA-2033488 https://reactome.org/PathwayBrowser/#/R-HSA-2033488 Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding TAS Homo sapiens 456216 R-HSA-2033490 https://reactome.org/PathwayBrowser/#/R-HSA-2033490 Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity TAS Homo sapiens 456216 R-HSA-2038387 https://reactome.org/PathwayBrowser/#/R-HSA-2038387 Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants TAS Homo sapiens 456216 R-HSA-2038944 https://reactome.org/PathwayBrowser/#/R-HSA-2038944 Autocatalytic phosphorylation of FGFR4 mutants with enhanced kinase activity TAS Homo sapiens 456216 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 456216 R-HSA-2046087 https://reactome.org/PathwayBrowser/#/R-HSA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes TAS Homo sapiens 456216 R-HSA-2046093 https://reactome.org/PathwayBrowser/#/R-HSA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes TAS Homo sapiens 456216 R-HSA-204949 https://reactome.org/PathwayBrowser/#/R-HSA-204949 NRIF and TRAF6 may activate JNK IEA Homo sapiens 456216 R-HSA-205075 https://reactome.org/PathwayBrowser/#/R-HSA-205075 JNK phosphorylates BIM, BAD and other targets TAS Homo sapiens 456216 R-HSA-205132 https://reactome.org/PathwayBrowser/#/R-HSA-205132 NRAGE activates JNK IEA Homo sapiens 456216 R-HSA-205136 https://reactome.org/PathwayBrowser/#/R-HSA-205136 GTP-bound RAC contributes to JNK activation TAS Homo sapiens 456216 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 456216 R-HSA-2060328 https://reactome.org/PathwayBrowser/#/R-HSA-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 TAS Homo sapiens 456216 R-HSA-209087 https://reactome.org/PathwayBrowser/#/R-HSA-209087 IKBA is phosphorylated by Phospho IKKB kinase TAS Homo sapiens 456216 R-HSA-210291 https://reactome.org/PathwayBrowser/#/R-HSA-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src TAS Homo sapiens 456216 R-HSA-210872 https://reactome.org/PathwayBrowser/#/R-HSA-210872 Trans-phosphorylation of Tie2 IEA Homo sapiens 456216 R-HSA-211164 https://reactome.org/PathwayBrowser/#/R-HSA-211164 AKT phosphorylates FOXO1A TAS Homo sapiens 456216 R-HSA-211583 https://reactome.org/PathwayBrowser/#/R-HSA-211583 Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197 IEA Homo sapiens 456216 R-HSA-211650 https://reactome.org/PathwayBrowser/#/R-HSA-211650 Autophosphorylation of PAK-2p34 in the activation loop IEA Homo sapiens 456216 R-HSA-212710 https://reactome.org/PathwayBrowser/#/R-HSA-212710 EGFR activates PLC-gamma1 by phosphorylation TAS Homo sapiens 456216 R-HSA-2130194 https://reactome.org/PathwayBrowser/#/R-HSA-2130194 ABL phosphorylates WAVEs TAS Homo sapiens 456216 R-HSA-2134532 https://reactome.org/PathwayBrowser/#/R-HSA-2134532 TGFBR2 phosphorylates TGFBR1 and PARD6A IEA Homo sapiens 456216 R-HSA-2161506 https://reactome.org/PathwayBrowser/#/R-HSA-2161506 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 456216 R-HSA-2161538 https://reactome.org/PathwayBrowser/#/R-HSA-2161538 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 456216 R-HSA-2162092 https://reactome.org/PathwayBrowser/#/R-HSA-2162092 carbovir monophosphate + ATP => carbovir diphosphate + ADP IEA Homo sapiens 456216 R-HSA-2162096 https://reactome.org/PathwayBrowser/#/R-HSA-2162096 carbovir diphosphate + ATP => carbovir triphosphate + ADP IEA Homo sapiens 456216 R-HSA-216723 https://reactome.org/PathwayBrowser/#/R-HSA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 456216 R-HSA-216757 https://reactome.org/PathwayBrowser/#/R-HSA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane TAS Homo sapiens 456216 R-HSA-2168079 https://reactome.org/PathwayBrowser/#/R-HSA-2168079 MASTL (GWL) phosphorylates ARPP19 TAS Homo sapiens 456216 R-HSA-2172183 https://reactome.org/PathwayBrowser/#/R-HSA-2172183 Phosphorylation of GORASP1, GOLGA2 and RAB1A by CDK1:CCNB IEA Homo sapiens 456216 R-HSA-2176475 https://reactome.org/PathwayBrowser/#/R-HSA-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 TAS Homo sapiens 456216 R-HSA-2197690 https://reactome.org/PathwayBrowser/#/R-HSA-2197690 Detachment of WASP/WAVE TAS Homo sapiens 456216 R-HSA-2197698 https://reactome.org/PathwayBrowser/#/R-HSA-2197698 Src phosphorylate WASP,N-WASP TAS Homo sapiens 456216 R-HSA-2201322 https://reactome.org/PathwayBrowser/#/R-HSA-2201322 TIRAP is phosphorylated by BTK TAS Homo sapiens 456216 R-HSA-2213248 https://reactome.org/PathwayBrowser/#/R-HSA-2213248 Transport of antigen loaded MHC II molecules to surface TAS Homo sapiens 456216 R-HSA-2214351 https://reactome.org/PathwayBrowser/#/R-HSA-2214351 PLK1 phosphorylates GORASP1 TAS Homo sapiens 456216 R-HSA-2220971 https://reactome.org/PathwayBrowser/#/R-HSA-2220971 CDK8 phosphorylates NICD1 PEST domain mutants TAS Homo sapiens 456216 R-HSA-2243938 https://reactome.org/PathwayBrowser/#/R-HSA-2243938 AKT1 E17K mutant is phosphorylated by TORC2 complex TAS Homo sapiens 456216 R-HSA-2243942 https://reactome.org/PathwayBrowser/#/R-HSA-2243942 PDPK1 phosphorylates AKT1 E17K mutant TAS Homo sapiens 456216 R-HSA-2245218 https://reactome.org/PathwayBrowser/#/R-HSA-2245218 CDK1 phosphorylates PHF8 TAS Homo sapiens 456216 R-HSA-2267372 https://reactome.org/PathwayBrowser/#/R-HSA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 TAS Homo sapiens 456216 R-HSA-2294580 https://reactome.org/PathwayBrowser/#/R-HSA-2294580 PLK1 hyperphosphorylates Condensin II complex TAS Homo sapiens 456216 R-HSA-2294600 https://reactome.org/PathwayBrowser/#/R-HSA-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 TAS Homo sapiens 456216 R-HSA-2316349 https://reactome.org/PathwayBrowser/#/R-HSA-2316349 RALA:GTP binds MYO1C:CALM1 and activates MYO1C IEA Homo sapiens 456216 R-HSA-2316352 https://reactome.org/PathwayBrowser/#/R-HSA-2316352 SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane IEA Homo sapiens 456216 R-HSA-2316434 https://reactome.org/PathwayBrowser/#/R-HSA-2316434 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-2394007 https://reactome.org/PathwayBrowser/#/R-HSA-2394007 PI3K gain of function mutants phosphorylate PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-2395412 https://reactome.org/PathwayBrowser/#/R-HSA-2395412 Phosphorylation of SYK TAS Homo sapiens 456216 R-HSA-2395439 https://reactome.org/PathwayBrowser/#/R-HSA-2395439 Phosphorylation of DAP12 IEA Homo sapiens 456216 R-HSA-2395801 https://reactome.org/PathwayBrowser/#/R-HSA-2395801 Phosphorylation of LAT by p-SYK TAS Homo sapiens 456216 R-HSA-2396002 https://reactome.org/PathwayBrowser/#/R-HSA-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex TAS Homo sapiens 456216 R-HSA-2396007 https://reactome.org/PathwayBrowser/#/R-HSA-2396007 IRF3 is phosphorylated by TBK1 TAS Homo sapiens 456216 R-HSA-2396594 https://reactome.org/PathwayBrowser/#/R-HSA-2396594 Phosphorylation of SLP-76 by p-SYK TAS Homo sapiens 456216 R-HSA-2399941 https://reactome.org/PathwayBrowser/#/R-HSA-2399941 AKT1 E17K mutant phosphorylates BAD TAS Homo sapiens 456216 R-HSA-2399966 https://reactome.org/PathwayBrowser/#/R-HSA-2399966 AKT1 E17K mutant phosphorylates GSK3 TAS Homo sapiens 456216 R-HSA-2399969 https://reactome.org/PathwayBrowser/#/R-HSA-2399969 AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1 TAS Homo sapiens 456216 R-HSA-2399977 https://reactome.org/PathwayBrowser/#/R-HSA-2399977 AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40) TAS Homo sapiens 456216 R-HSA-2399981 https://reactome.org/PathwayBrowser/#/R-HSA-2399981 AKT1 E17K mutant phosphorylates MDM2 TAS Homo sapiens 456216 R-HSA-2399982 https://reactome.org/PathwayBrowser/#/R-HSA-2399982 AKT1 E17K mutant phosphorylates TSC2, inhibiting it TAS Homo sapiens 456216 R-HSA-2399985 https://reactome.org/PathwayBrowser/#/R-HSA-2399985 AKT1 E17K mutant phosphorylates caspase-9 TAS Homo sapiens 456216 R-HSA-2399988 https://reactome.org/PathwayBrowser/#/R-HSA-2399988 AKT1 E17K mutant phosphorylates NR4A1 (NUR77) TAS Homo sapiens 456216 R-HSA-2399992 https://reactome.org/PathwayBrowser/#/R-HSA-2399992 AKT1 E17K mutant phosphorylates forkhead box transcription factors TAS Homo sapiens 456216 R-HSA-2399996 https://reactome.org/PathwayBrowser/#/R-HSA-2399996 AKT1 E17K mutant phosphorylates CREB1 TAS Homo sapiens 456216 R-HSA-2399999 https://reactome.org/PathwayBrowser/#/R-HSA-2399999 AKT1 E17K mutant phosphorylates RSK TAS Homo sapiens 456216 R-HSA-2400001 https://reactome.org/PathwayBrowser/#/R-HSA-2400001 AKT1 E17K mutant phosphorylates CHUK (IKKalpha) TAS Homo sapiens 456216 R-HSA-2404193 https://reactome.org/PathwayBrowser/#/R-HSA-2404193 IGF1R phosphorylates SHC1 TAS Homo sapiens 456216 R-HSA-2404199 https://reactome.org/PathwayBrowser/#/R-HSA-2404199 IGF1,2:IGF1R autophosphorylates TAS Homo sapiens 456216 R-HSA-2408507 https://reactome.org/PathwayBrowser/#/R-HSA-2408507 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK IEA Homo sapiens 456216 R-HSA-2408540 https://reactome.org/PathwayBrowser/#/R-HSA-2408540 APSe is phosphorylated to PAPSe by PAPSS1,2 IEA Homo sapiens 456216 R-HSA-2422927 https://reactome.org/PathwayBrowser/#/R-HSA-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 TAS Homo sapiens 456216 R-HSA-2424480 https://reactome.org/PathwayBrowser/#/R-HSA-2424480 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-2424484 https://reactome.org/PathwayBrowser/#/R-HSA-2424484 Phosphorylation of BTK by p-SYK TAS Homo sapiens 456216 R-HSA-2424486 https://reactome.org/PathwayBrowser/#/R-HSA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK TAS Homo sapiens 456216 R-HSA-2424487 https://reactome.org/PathwayBrowser/#/R-HSA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK TAS Homo sapiens 456216 R-HSA-2428926 https://reactome.org/PathwayBrowser/#/R-HSA-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 TAS Homo sapiens 456216 R-HSA-2430533 https://reactome.org/PathwayBrowser/#/R-HSA-2430533 CDK1 phosphorylates MASTL IEA Homo sapiens 456216 R-HSA-2430535 https://reactome.org/PathwayBrowser/#/R-HSA-2430535 MASTL phosphorylates ENSA TAS Homo sapiens 456216 R-HSA-2454208 https://reactome.org/PathwayBrowser/#/R-HSA-2454208 Phosphorylation of beta and gamma subunits by LYN TAS Homo sapiens 456216 R-HSA-2454239 https://reactome.org/PathwayBrowser/#/R-HSA-2454239 Phosphorylation of SYK IEA Homo sapiens 456216 R-HSA-2466068 https://reactome.org/PathwayBrowser/#/R-HSA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms TAS Homo sapiens 456216 R-HSA-2466749 https://reactome.org/PathwayBrowser/#/R-HSA-2466749 ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol IEA Homo sapiens 456216 R-HSA-2468287 https://reactome.org/PathwayBrowser/#/R-HSA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres TAS Homo sapiens 456216 R-HSA-2468293 https://reactome.org/PathwayBrowser/#/R-HSA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms TAS Homo sapiens 456216 R-HSA-2470508 https://reactome.org/PathwayBrowser/#/R-HSA-2470508 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin IEA Homo sapiens 456216 R-HSA-2514854 https://reactome.org/PathwayBrowser/#/R-HSA-2514854 CDK1 phosphorylates condensin I IEA Homo sapiens 456216 R-HSA-2529020 https://reactome.org/PathwayBrowser/#/R-HSA-2529020 CK2 phosphorylates condensin I subunits TAS Homo sapiens 456216 R-HSA-2562526 https://reactome.org/PathwayBrowser/#/R-HSA-2562526 PLK1 phosphorylates OPTN TAS Homo sapiens 456216 R-HSA-2574840 https://reactome.org/PathwayBrowser/#/R-HSA-2574840 AJUBA facilitates AURKA autophosphorylation TAS Homo sapiens 456216 R-HSA-2581474 https://reactome.org/PathwayBrowser/#/R-HSA-2581474 GRK1,4,7 phosphorylate MII to p-MII TAS Homo sapiens 456216 R-HSA-2586553 https://reactome.org/PathwayBrowser/#/R-HSA-2586553 JAK2 Phosphorylates LEPR IEA Homo sapiens 456216 R-HSA-2586555 https://reactome.org/PathwayBrowser/#/R-HSA-2586555 JAK2 Autophosphorylates in Response to Leptin IEA Homo sapiens 456216 R-HSA-265682 https://reactome.org/PathwayBrowser/#/R-HSA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel TAS Homo sapiens 456216 R-HSA-265783 https://reactome.org/PathwayBrowser/#/R-HSA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-266082 https://reactome.org/PathwayBrowser/#/R-HSA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface TAS Homo sapiens 456216 R-HSA-2671742 https://reactome.org/PathwayBrowser/#/R-HSA-2671742 JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin IEA Homo sapiens 456216 R-HSA-2671829 https://reactome.org/PathwayBrowser/#/R-HSA-2671829 JAK2 Phosphorylates STAT5 in Response to Leptin IEA Homo sapiens 456216 R-HSA-2671850 https://reactome.org/PathwayBrowser/#/R-HSA-2671850 JAK2 Phosphoryates STAT3 in Response to Leptin IEA Homo sapiens 456216 R-HSA-2671862 https://reactome.org/PathwayBrowser/#/R-HSA-2671862 JAK2 Phosphorylates IRS in Response to Leptin IEA Homo sapiens 456216 R-HSA-2682349 https://reactome.org/PathwayBrowser/#/R-HSA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels TAS Homo sapiens 456216 R-HSA-2730833 https://reactome.org/PathwayBrowser/#/R-HSA-2730833 Phosphorylation of TEC kinases by p-SYK TAS Homo sapiens 456216 R-HSA-2730835 https://reactome.org/PathwayBrowser/#/R-HSA-2730835 Autophosphorylation of PKC-theta TAS Homo sapiens 456216 R-HSA-2730841 https://reactome.org/PathwayBrowser/#/R-HSA-2730841 Phosphorylation and activation of VAV TAS Homo sapiens 456216 R-HSA-2730843 https://reactome.org/PathwayBrowser/#/R-HSA-2730843 Phosphorylation of LAT by p-SYK TAS Homo sapiens 456216 R-HSA-2730851 https://reactome.org/PathwayBrowser/#/R-HSA-2730851 Phosphorylation of SLP-76 by p-SYK TAS Homo sapiens 456216 R-HSA-2730856 https://reactome.org/PathwayBrowser/#/R-HSA-2730856 Autophosphorylation of PAK TAS Homo sapiens 456216 R-HSA-2730858 https://reactome.org/PathwayBrowser/#/R-HSA-2730858 Autophosphorylation of BTK/ITK TAS Homo sapiens 456216 R-HSA-2730860 https://reactome.org/PathwayBrowser/#/R-HSA-2730860 Phosphorylation of GAB2 by SYK/FYN IEA Homo sapiens 456216 R-HSA-2730862 https://reactome.org/PathwayBrowser/#/R-HSA-2730862 Autophosphorylation of LYN kinase TAS Homo sapiens 456216 R-HSA-2730863 https://reactome.org/PathwayBrowser/#/R-HSA-2730863 Phosphorylation of CARMA1 by PKC-theta TAS Homo sapiens 456216 R-HSA-2730868 https://reactome.org/PathwayBrowser/#/R-HSA-2730868 Phosphorylation of MEK7 by MEKK1 TAS Homo sapiens 456216 R-HSA-2730870 https://reactome.org/PathwayBrowser/#/R-HSA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K TAS Homo sapiens 456216 R-HSA-2730876 https://reactome.org/PathwayBrowser/#/R-HSA-2730876 Phosphorylation of IKK-beta by TAK1 TAS Homo sapiens 456216 R-HSA-2730882 https://reactome.org/PathwayBrowser/#/R-HSA-2730882 Phosphorylation of PKC-theta TAS Homo sapiens 456216 R-HSA-2730884 https://reactome.org/PathwayBrowser/#/R-HSA-2730884 Phosphorylation of NTAL by p-SYK/Lyn TAS Homo sapiens 456216 R-HSA-2730886 https://reactome.org/PathwayBrowser/#/R-HSA-2730886 Phosphorylation of SHC by SYK kinase TAS Homo sapiens 456216 R-HSA-2730887 https://reactome.org/PathwayBrowser/#/R-HSA-2730887 Autophosphorylation and activation of MEKK1 IEA Homo sapiens 456216 R-HSA-2730888 https://reactome.org/PathwayBrowser/#/R-HSA-2730888 Phosphorylation of PLC-gamma IEA Homo sapiens 456216 R-HSA-2730896 https://reactome.org/PathwayBrowser/#/R-HSA-2730896 Phosphorylation of MEK4 by MEKK1 TAS Homo sapiens 456216 R-HSA-2730900 https://reactome.org/PathwayBrowser/#/R-HSA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 TAS Homo sapiens 456216 R-HSA-2984220 https://reactome.org/PathwayBrowser/#/R-HSA-2984220 CDK1:CCNB phosphorylates NEK9 TAS Homo sapiens 456216 R-HSA-2984226 https://reactome.org/PathwayBrowser/#/R-HSA-2984226 PLK1 phosphorylates NEK9 TAS Homo sapiens 456216 R-HSA-2984258 https://reactome.org/PathwayBrowser/#/R-HSA-2984258 NEK9 phosphorylates NEK6/NEK7 TAS Homo sapiens 456216 R-HSA-2990880 https://reactome.org/PathwayBrowser/#/R-HSA-2990880 NEK6/NEK7 phosphorylates NUP98 TAS Homo sapiens 456216 R-HSA-2990882 https://reactome.org/PathwayBrowser/#/R-HSA-2990882 CDK1 phosphorylates NUP98 TAS Homo sapiens 456216 R-HSA-2993898 https://reactome.org/PathwayBrowser/#/R-HSA-2993898 VRK1/VRK2 phosphorylate BANF1 TAS Homo sapiens 456216 R-HSA-3000310 https://reactome.org/PathwayBrowser/#/R-HSA-3000310 AURKA phosphorylates PLK1 TAS Homo sapiens 456216 R-HSA-3000327 https://reactome.org/PathwayBrowser/#/R-HSA-3000327 PLK1 phosphorylates BORA TAS Homo sapiens 456216 R-HSA-3095901 https://reactome.org/PathwayBrowser/#/R-HSA-3095901 ABCC1 transports cytosolic RCbl to extracellular region TAS Homo sapiens 456216 R-HSA-3132737 https://reactome.org/PathwayBrowser/#/R-HSA-3132737 MAPKs phosphorylate ETS1 and ETS2 TAS Homo sapiens 456216 R-HSA-3134904 https://reactome.org/PathwayBrowser/#/R-HSA-3134904 Phosphorylation of beta-catenin at Ser552 TAS Homo sapiens 456216 R-HSA-3209160 https://reactome.org/PathwayBrowser/#/R-HSA-3209160 Activated ERKs phosphorylate ERF IEA Homo sapiens 456216 R-HSA-3215391 https://reactome.org/PathwayBrowser/#/R-HSA-3215391 PRMT5 is tyrosine phosphorylated by JAK2 V617F TAS Homo sapiens 456216 R-HSA-3222006 https://reactome.org/PathwayBrowser/#/R-HSA-3222006 STK11 (LKB1) phosphorylates NUAK1 TAS Homo sapiens 456216 R-HSA-3222020 https://reactome.org/PathwayBrowser/#/R-HSA-3222020 NUAK1 phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-3228469 https://reactome.org/PathwayBrowser/#/R-HSA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 TAS Homo sapiens 456216 R-HSA-3229102 https://reactome.org/PathwayBrowser/#/R-HSA-3229102 p-MAPKAPK3 phosphorylates BMI1 TAS Homo sapiens 456216 R-HSA-3229152 https://reactome.org/PathwayBrowser/#/R-HSA-3229152 MAP3K5 (ASK1) phosphorylates MAP2K4 (SEK1) IEA Homo sapiens 456216 R-HSA-3238999 https://reactome.org/PathwayBrowser/#/R-HSA-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 TAS Homo sapiens 456216 R-HSA-3239014 https://reactome.org/PathwayBrowser/#/R-HSA-3239014 MAPKAPK5 phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-3239019 https://reactome.org/PathwayBrowser/#/R-HSA-3239019 Active p38 MAPK phosphorylates MAPKAPK5 TAS Homo sapiens 456216 R-HSA-3249371 https://reactome.org/PathwayBrowser/#/R-HSA-3249371 TBK1 phosphorylates STAT6 at Ser407 TAS Homo sapiens 456216 R-HSA-3249379 https://reactome.org/PathwayBrowser/#/R-HSA-3249379 p-S407-STAT6 is phosphorylated at Tyr641 TAS Homo sapiens 456216 R-HSA-3249390 https://reactome.org/PathwayBrowser/#/R-HSA-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex TAS Homo sapiens 456216 R-HSA-3371422 https://reactome.org/PathwayBrowser/#/R-HSA-3371422 ATP hydrolysis by HSP70 TAS Homo sapiens 456216 R-HSA-3371435 https://reactome.org/PathwayBrowser/#/R-HSA-3371435 Constitutive phosphorylation by GSK3 TAS Homo sapiens 456216 R-HSA-3371503 https://reactome.org/PathwayBrowser/#/R-HSA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein TAS Homo sapiens 456216 R-HSA-3371531 https://reactome.org/PathwayBrowser/#/R-HSA-3371531 Constitutive phosphorylation by pERK1/2 TAS Homo sapiens 456216 R-HSA-3371567 https://reactome.org/PathwayBrowser/#/R-HSA-3371567 DBC1 is phosphorylated by ATM/ART TAS Homo sapiens 456216 R-HSA-349426 https://reactome.org/PathwayBrowser/#/R-HSA-349426 Phosphorylation of MDM4 by CHEK2 TAS Homo sapiens 456216 R-HSA-349444 https://reactome.org/PathwayBrowser/#/R-HSA-349444 Phosphorylation of COP1 at Ser-387 by ATM TAS Homo sapiens 456216 R-HSA-349455 https://reactome.org/PathwayBrowser/#/R-HSA-349455 Phosphorylation of MDM4 by ATM TAS Homo sapiens 456216 R-HSA-349520 https://reactome.org/PathwayBrowser/#/R-HSA-349520 Re-acidification of acetylcholine transport vesicles TAS Homo sapiens 456216 R-HSA-354073 https://reactome.org/PathwayBrowser/#/R-HSA-354073 Autophosphorylation of PTK2 at Y397 TAS Homo sapiens 456216 R-HSA-354124 https://reactome.org/PathwayBrowser/#/R-HSA-354124 Phosphorylation of pPTK2 by SRC TAS Homo sapiens 456216 R-HSA-3697838 https://reactome.org/PathwayBrowser/#/R-HSA-3697838 ATP7A transfers Cu from ATOX1 to SOD3 IEA Homo sapiens 456216 R-HSA-372693 https://reactome.org/PathwayBrowser/#/R-HSA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex TAS Homo sapiens 456216 R-HSA-373747 https://reactome.org/PathwayBrowser/#/R-HSA-373747 Phosphorylation of nephrin by FYN TAS Homo sapiens 456216 R-HSA-373750 https://reactome.org/PathwayBrowser/#/R-HSA-373750 SEMA4D interacts with Plexin-B1:ErbB2 TAS Homo sapiens 456216 R-HSA-374664 https://reactome.org/PathwayBrowser/#/R-HSA-374664 Phosphorylation and activation of Ezrin TAS Homo sapiens 456216 R-HSA-374696 https://reactome.org/PathwayBrowser/#/R-HSA-374696 Phosphorylation of L1 by p90rsk IEA Homo sapiens 456216 R-HSA-374701 https://reactome.org/PathwayBrowser/#/R-HSA-374701 Phosphorylation of DCC by Fyn TAS Homo sapiens 456216 R-HSA-374916 https://reactome.org/PathwayBrowser/#/R-HSA-374916 Re-acidification of clathrin sculpted monoamine transport vesicle lumen TAS Homo sapiens 456216 R-HSA-3769394 https://reactome.org/PathwayBrowser/#/R-HSA-3769394 AKT phosphorylates CBY1 TAS Homo sapiens 456216 R-HSA-377186 https://reactome.org/PathwayBrowser/#/R-HSA-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) TAS Homo sapiens 456216 R-HSA-3772435 https://reactome.org/PathwayBrowser/#/R-HSA-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL TAS Homo sapiens 456216 R-HSA-3772436 https://reactome.org/PathwayBrowser/#/R-HSA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 TAS Homo sapiens 456216 R-HSA-377640 https://reactome.org/PathwayBrowser/#/R-HSA-377640 Autophosphorylation of SRC TAS Homo sapiens 456216 R-HSA-3788705 https://reactome.org/PathwayBrowser/#/R-HSA-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 TAS Homo sapiens 456216 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 456216 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 456216 R-HSA-380272 https://reactome.org/PathwayBrowser/#/R-HSA-380272 Plk1-mediated phosphorylation of Nlp TAS Homo sapiens 456216 R-HSA-380278 https://reactome.org/PathwayBrowser/#/R-HSA-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 TAS Homo sapiens 456216 R-HSA-380780 https://reactome.org/PathwayBrowser/#/R-HSA-380780 Activation of Src TAS Homo sapiens 456216 R-HSA-380927 https://reactome.org/PathwayBrowser/#/R-HSA-380927 p-AMPK phosphorylates TSC1:TSC2 TAS Homo sapiens 456216 R-HSA-381091 https://reactome.org/PathwayBrowser/#/R-HSA-381091 IRE1 dimer autophosphorylates TAS Homo sapiens 456216 R-HSA-381111 https://reactome.org/PathwayBrowser/#/R-HSA-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK TAS Homo sapiens 456216 R-HSA-381116 https://reactome.org/PathwayBrowser/#/R-HSA-381116 Phosphorylated IRE1 dimer binds ADP IEA Homo sapiens 456216 R-HSA-382553 https://reactome.org/PathwayBrowser/#/R-HSA-382553 ABCA7:Apo1A-mediated phospholipid efflux TAS Homo sapiens 456216 R-HSA-382560 https://reactome.org/PathwayBrowser/#/R-HSA-382560 ABC7, mABC1 and mABC2 mediate heme transport TAS Homo sapiens 456216 R-HSA-382575 https://reactome.org/PathwayBrowser/#/R-HSA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix TAS Homo sapiens 456216 R-HSA-383190 https://reactome.org/PathwayBrowser/#/R-HSA-383190 HCO3- transport through ion channel TAS Homo sapiens 456216 R-HSA-3857328 https://reactome.org/PathwayBrowser/#/R-HSA-3857328 RPS6KA1/2/3 phosphorylates CEBPB on S321 IEA Homo sapiens 456216 R-HSA-3857329 https://reactome.org/PathwayBrowser/#/R-HSA-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB TAS Homo sapiens 456216 R-HSA-3858480 https://reactome.org/PathwayBrowser/#/R-HSA-3858480 WNT-dependent phosphorylation of DVL IEA Homo sapiens 456216 R-HSA-388831 https://reactome.org/PathwayBrowser/#/R-HSA-388831 Phosphorylation of CD28 TAS Homo sapiens 456216 R-HSA-388833 https://reactome.org/PathwayBrowser/#/R-HSA-388833 Phosphorylation of CTLA-4 TAS Homo sapiens 456216 R-HSA-389083 https://reactome.org/PathwayBrowser/#/R-HSA-389083 Autophosphorylation of PDGF alpha receptors TAS Homo sapiens 456216 R-HSA-389086 https://reactome.org/PathwayBrowser/#/R-HSA-389086 Autophosphorylation of PDGF alpha/beta receptors TAS Homo sapiens 456216 R-HSA-389158 https://reactome.org/PathwayBrowser/#/R-HSA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-389159 https://reactome.org/PathwayBrowser/#/R-HSA-389159 CSF1R trans-autophosphorylates on multiple tyrosine and serine residues IEA Homo sapiens 456216 R-HSA-389354 https://reactome.org/PathwayBrowser/#/R-HSA-389354 Activation of Vav1 TAS Homo sapiens 456216 R-HSA-389756 https://reactome.org/PathwayBrowser/#/R-HSA-389756 AKT interacts and phosphorylates Cot TAS Homo sapiens 456216 R-HSA-389762 https://reactome.org/PathwayBrowser/#/R-HSA-389762 Phosphorylation of PD-1 TAS Homo sapiens 456216 R-HSA-389954 https://reactome.org/PathwayBrowser/#/R-HSA-389954 Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC IEA Homo sapiens 456216 R-HSA-389961 https://reactome.org/PathwayBrowser/#/R-HSA-389961 ADP is exchanged for ATP in the (ADP:CCT/TriC):tubulin complex IEA Homo sapiens 456216 R-HSA-389970 https://reactome.org/PathwayBrowser/#/R-HSA-389970 Actin/tubulin:prefoldin complex associates with CCT/TriC IEA Homo sapiens 456216 R-HSA-390453 https://reactome.org/PathwayBrowser/#/R-HSA-390453 Hydrolysis of ATP and release of folded actin from CCT/TriC IEA Homo sapiens 456216 R-HSA-390459 https://reactome.org/PathwayBrowser/#/R-HSA-390459 Exchange of ADP for ATP in CCT/TriC:actin complex IEA Homo sapiens 456216 R-HSA-390470 https://reactome.org/PathwayBrowser/#/R-HSA-390470 Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) IEA Homo sapiens 456216 R-HSA-390593 https://reactome.org/PathwayBrowser/#/R-HSA-390593 ATP Hydrolysis By Myosin TAS Homo sapiens 456216 R-HSA-390597 https://reactome.org/PathwayBrowser/#/R-HSA-390597 Release Of ADP From Myosin TAS Homo sapiens 456216 R-HSA-391156 https://reactome.org/PathwayBrowser/#/R-HSA-391156 Phosphorylation of ITIM motif in SIRP alpha IEA Homo sapiens 456216 R-HSA-391266 https://reactome.org/PathwayBrowser/#/R-HSA-391266 Association of CCT/TriC with sphingosine kinase 1 TAS Homo sapiens 456216 R-HSA-391865 https://reactome.org/PathwayBrowser/#/R-HSA-391865 Recruitment of FAK to NCAM1:Fyn in lipid rafts IEA Homo sapiens 456216 R-HSA-391866 https://reactome.org/PathwayBrowser/#/R-HSA-391866 Phosphorylation of FAK by Src kinase IEA Homo sapiens 456216 R-HSA-391871 https://reactome.org/PathwayBrowser/#/R-HSA-391871 Autophosphorylation of NCAM1 bound Fyn IEA Homo sapiens 456216 R-HSA-392187 https://reactome.org/PathwayBrowser/#/R-HSA-392187 Activated P2Y purinoceptor 12 binds G-protein Gi TAS Homo sapiens 456216 R-HSA-392195 https://reactome.org/PathwayBrowser/#/R-HSA-392195 Gi activation by P2Y purinoceptor 12 TAS Homo sapiens 456216 R-HSA-392202 https://reactome.org/PathwayBrowser/#/R-HSA-392202 Dissociation of the P2Y purinoceptor 12:Gi complex TAS Homo sapiens 456216 R-HSA-392300 https://reactome.org/PathwayBrowser/#/R-HSA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-392530 https://reactome.org/PathwayBrowser/#/R-HSA-392530 p-S400-Cot phosphorylates NIK TAS Homo sapiens 456216 R-HSA-392752 https://reactome.org/PathwayBrowser/#/R-HSA-392752 Phosphorylation of L1 by CK-II TAS Homo sapiens 456216 R-HSA-3928577 https://reactome.org/PathwayBrowser/#/R-HSA-3928577 ROCK phosphorylates LIMK1,2 IEA Homo sapiens 456216 R-HSA-3928578 https://reactome.org/PathwayBrowser/#/R-HSA-3928578 EPH receptors autophosphorylate TAS Homo sapiens 456216 R-HSA-3928580 https://reactome.org/PathwayBrowser/#/R-HSA-3928580 SFKs phosphorylate EFNBs IEA Homo sapiens 456216 R-HSA-3928583 https://reactome.org/PathwayBrowser/#/R-HSA-3928583 FYN phosphorylates NMDAR2B IEA Homo sapiens 456216 R-HSA-3928594 https://reactome.org/PathwayBrowser/#/R-HSA-3928594 SFKs phosphorylate GIT1 IEA Homo sapiens 456216 R-HSA-3928604 https://reactome.org/PathwayBrowser/#/R-HSA-3928604 SFKs phosphorylate VAV2,3 TAS Homo sapiens 456216 R-HSA-3928608 https://reactome.org/PathwayBrowser/#/R-HSA-3928608 LIMK phosphorylates CFL1, inactivating it IEA Homo sapiens 456216 R-HSA-3928610 https://reactome.org/PathwayBrowser/#/R-HSA-3928610 PTK2 autophosphorylates at Y397 IEA Homo sapiens 456216 R-HSA-3928616 https://reactome.org/PathwayBrowser/#/R-HSA-3928616 Activated ROCK phosphorylates MRLCs IEA Homo sapiens 456216 R-HSA-3928620 https://reactome.org/PathwayBrowser/#/R-HSA-3928620 PAK1 autophosphorylates TAS Homo sapiens 456216 R-HSA-3928625 https://reactome.org/PathwayBrowser/#/R-HSA-3928625 PAKs autophosphorylate TAS Homo sapiens 456216 R-HSA-3928627 https://reactome.org/PathwayBrowser/#/R-HSA-3928627 EPHB phosphorylates TIAM1 TAS Homo sapiens 456216 R-HSA-3928640 https://reactome.org/PathwayBrowser/#/R-HSA-3928640 PAKs phosphorylate MLC TAS Homo sapiens 456216 R-HSA-3928648 https://reactome.org/PathwayBrowser/#/R-HSA-3928648 SFKs phosphorylate NGEF IEA Homo sapiens 456216 R-HSA-399934 https://reactome.org/PathwayBrowser/#/R-HSA-399934 Phosphorylation of Plexin-A IEA Homo sapiens 456216 R-HSA-399939 https://reactome.org/PathwayBrowser/#/R-HSA-399939 Autophosphorylation of PAK TAS Homo sapiens 456216 R-HSA-399944 https://reactome.org/PathwayBrowser/#/R-HSA-399944 Phosphorylation of CRMPs by Cdk5 TAS Homo sapiens 456216 R-HSA-399946 https://reactome.org/PathwayBrowser/#/R-HSA-399946 Recruitment and activation of Cdk5 IEA Homo sapiens 456216 R-HSA-399947 https://reactome.org/PathwayBrowser/#/R-HSA-399947 Tyrosine phosphorylation of CRMPs by Fes TAS Homo sapiens 456216 R-HSA-399950 https://reactome.org/PathwayBrowser/#/R-HSA-399950 Phosphorylation of cofilin by LIMK-1 IEA Homo sapiens 456216 R-HSA-399951 https://reactome.org/PathwayBrowser/#/R-HSA-399951 Phosphorylation of CRMPs by GSK3beta TAS Homo sapiens 456216 R-HSA-399952 https://reactome.org/PathwayBrowser/#/R-HSA-399952 Phosphorylation of LIMK-1 by PAK TAS Homo sapiens 456216 R-HSA-399978 https://reactome.org/PathwayBrowser/#/R-HSA-399978 Protein kinase C, alpha type phosphorylates MARCKS TAS Homo sapiens 456216 R-HSA-400382 https://reactome.org/PathwayBrowser/#/R-HSA-400382 CSNK1E,CSNK1D phosphorylate CRY and PER proteins IEA Homo sapiens 456216 R-HSA-4085028 https://reactome.org/PathwayBrowser/#/R-HSA-4085028 GNE phosphorylates ManNAc to ManNAc-6-P TAS Homo sapiens 456216 R-HSA-4086410 https://reactome.org/PathwayBrowser/#/R-HSA-4086410 CDK1 phosphorylates BORA TAS Homo sapiens 456216 R-HSA-4088024 https://reactome.org/PathwayBrowser/#/R-HSA-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 TAS Homo sapiens 456216 R-HSA-4088134 https://reactome.org/PathwayBrowser/#/R-HSA-4088134 PLK1 phosphorylates FOXM1 TAS Homo sapiens 456216 R-HSA-4093332 https://reactome.org/PathwayBrowser/#/R-HSA-4093332 p-EPHB phosphorylates SDC2 TAS Homo sapiens 456216 R-HSA-416320 https://reactome.org/PathwayBrowser/#/R-HSA-416320 Trafficking of GluR1-containing AMPA receptors TAS Homo sapiens 456216 R-HSA-416639 https://reactome.org/PathwayBrowser/#/R-HSA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites TAS Homo sapiens 456216 R-HSA-416985 https://reactome.org/PathwayBrowser/#/R-HSA-416985 Trafficking of GluR2-containing AMPA receptors to synapse TAS Homo sapiens 456216 R-HSA-417829 https://reactome.org/PathwayBrowser/#/R-HSA-417829 P2RY12 binds ADP TAS Homo sapiens 456216 R-HSA-417843 https://reactome.org/PathwayBrowser/#/R-HSA-417843 P2Y13 binds ADP TAS Homo sapiens 456216 R-HSA-417908 https://reactome.org/PathwayBrowser/#/R-HSA-417908 P2RY1 binds ADP TAS Homo sapiens 456216 R-HSA-418576 https://reactome.org/PathwayBrowser/#/R-HSA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex TAS Homo sapiens 456216 R-HSA-418579 https://reactome.org/PathwayBrowser/#/R-HSA-418579 Gq activation by P2Y purinoceptor 1 IEA Homo sapiens 456216 R-HSA-418581 https://reactome.org/PathwayBrowser/#/R-HSA-418581 Activated P2Y purinoceptor 1 binds G-protein Gq IEA Homo sapiens 456216 R-HSA-418845 https://reactome.org/PathwayBrowser/#/R-HSA-418845 Activation of caspase-3 TAS Homo sapiens 456216 R-HSA-418859 https://reactome.org/PathwayBrowser/#/R-HSA-418859 Phosphorylation of Unc5C IEA Homo sapiens 456216 R-HSA-418872 https://reactome.org/PathwayBrowser/#/R-HSA-418872 Phosphorylation of FADK1 IEA Homo sapiens 456216 R-HSA-419083 https://reactome.org/PathwayBrowser/#/R-HSA-419083 Myosin phosphatase inactivation by ROCK IEA Homo sapiens 456216 R-HSA-419087 https://reactome.org/PathwayBrowser/#/R-HSA-419087 LIM kinase phosphorylation by ROCK IEA Homo sapiens 456216 R-HSA-419197 https://reactome.org/PathwayBrowser/#/R-HSA-419197 Myosin regulatory light chain phosphorylation by ROCK IEA Homo sapiens 456216 R-HSA-419644 https://reactome.org/PathwayBrowser/#/R-HSA-419644 Transphosphorylation of pLIMK1 TAS Homo sapiens 456216 R-HSA-419646 https://reactome.org/PathwayBrowser/#/R-HSA-419646 SEMA4D interacts with Plexin-B1:Met TAS Homo sapiens 456216 R-HSA-421007 https://reactome.org/PathwayBrowser/#/R-HSA-421007 Endocytosis of Ca impermeable AMPA receptors TAS Homo sapiens 456216 R-HSA-421836 https://reactome.org/PathwayBrowser/#/R-HSA-421836 trans-Golgi Network Derived Vesicle Uncoating TAS Homo sapiens 456216 R-HSA-425923 https://reactome.org/PathwayBrowser/#/R-HSA-425923 IRE1alpha hydrolyzes Xbp1 mRNA and Xbp1 mRNA is spliced TAS Homo sapiens 456216 R-HSA-426240 https://reactome.org/PathwayBrowser/#/R-HSA-426240 DAG kinase produces phosphatidic acid from DAG TAS Homo sapiens 456216 R-HSA-428273 https://reactome.org/PathwayBrowser/#/R-HSA-428273 SPHK1 phosphorylates sphingoid TAS Homo sapiens 456216 R-HSA-428888 https://reactome.org/PathwayBrowser/#/R-HSA-428888 Phosphorylation of ROBO1 by ABL kinase TAS Homo sapiens 456216 R-HSA-428941 https://reactome.org/PathwayBrowser/#/R-HSA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha TAS Homo sapiens 456216 R-HSA-428961 https://reactome.org/PathwayBrowser/#/R-HSA-428961 Phosphorylation of cPLA2 by MAPK p38 alpha TAS Homo sapiens 456216 R-HSA-429016 https://reactome.org/PathwayBrowser/#/R-HSA-429016 ALOX5 is phosphorylated by MAPKAP2 TAS Homo sapiens 456216 R-HSA-429157 https://reactome.org/PathwayBrowser/#/R-HSA-429157 ABCC4 accumulation of dense granule contents TAS Homo sapiens 456216 R-HSA-429441 https://reactome.org/PathwayBrowser/#/R-HSA-429441 SYK activation by SRC TAS Homo sapiens 456216 R-HSA-429449 https://reactome.org/PathwayBrowser/#/R-HSA-429449 Syk activation leads to SLP-76 activation TAS Homo sapiens 456216 R-HSA-429698 https://reactome.org/PathwayBrowser/#/R-HSA-429698 PRKD1,2,3 phosphorylates CERT1-2 TAS Homo sapiens 456216 R-HSA-429714 https://reactome.org/PathwayBrowser/#/R-HSA-429714 CSNK1G2 phosphorylates p-CERT1-2 TAS Homo sapiens 456216 R-HSA-432129 https://reactome.org/PathwayBrowser/#/R-HSA-432129 FGR binds and phosphorylates LRP8 TAS Homo sapiens 456216 R-HSA-432148 https://reactome.org/PathwayBrowser/#/R-HSA-432148 Fgr may phosphorylate p38 MAPK TAS Homo sapiens 456216 R-HSA-432232 https://reactome.org/PathwayBrowser/#/R-HSA-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) TAS Homo sapiens 456216 R-HSA-432688 https://reactome.org/PathwayBrowser/#/R-HSA-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating TAS Homo sapiens 456216 R-HSA-4332358 https://reactome.org/PathwayBrowser/#/R-HSA-4332358 Dissociation of CaM and CAMK2 autophosphorylation TAS Homo sapiens 456216 R-HSA-4332363 https://reactome.org/PathwayBrowser/#/R-HSA-4332363 Autophosphorylation and activation of CAMK2 TAS Homo sapiens 456216 R-HSA-4332388 https://reactome.org/PathwayBrowser/#/R-HSA-4332388 Activation of MAP3K7 in response to WNT TAS Homo sapiens 456216 R-HSA-434836 https://reactome.org/PathwayBrowser/#/R-HSA-434836 Syk/Lck phosphorylate LAT TAS Homo sapiens 456216 R-HSA-435244 https://reactome.org/PathwayBrowser/#/R-HSA-435244 PECAM1 is phosphorylated TAS Homo sapiens 456216 R-HSA-437162 https://reactome.org/PathwayBrowser/#/R-HSA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-437195 https://reactome.org/PathwayBrowser/#/R-HSA-437195 PDPK1 activates PRKCZ IEA Homo sapiens 456216 R-HSA-437936 https://reactome.org/PathwayBrowser/#/R-HSA-437936 p-Y348-SYK phosphorylates VAV family IEA Homo sapiens 456216 R-HSA-4411383 https://reactome.org/PathwayBrowser/#/R-HSA-4411383 NLK phosphorylates TCF/LEF TAS Homo sapiens 456216 R-HSA-4411402 https://reactome.org/PathwayBrowser/#/R-HSA-4411402 Activation of NLK TAS Homo sapiens 456216 R-HSA-4420117 https://reactome.org/PathwayBrowser/#/R-HSA-4420117 VEGFR2 autophosphorylates TAS Homo sapiens 456216 R-HSA-4420121 https://reactome.org/PathwayBrowser/#/R-HSA-4420121 SFKs phosphorylate PLCG1 TAS Homo sapiens 456216 R-HSA-4420128 https://reactome.org/PathwayBrowser/#/R-HSA-4420128 SRC-1 phosphorylates SHB TAS Homo sapiens 456216 R-HSA-4420206 https://reactome.org/PathwayBrowser/#/R-HSA-4420206 Phosphorylation of SRC-1 TAS Homo sapiens 456216 R-HSA-442724 https://reactome.org/PathwayBrowser/#/R-HSA-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) TAS Homo sapiens 456216 R-HSA-442739 https://reactome.org/PathwayBrowser/#/R-HSA-442739 PDPK1 phosphorylates RSKs IEA Homo sapiens 456216 R-HSA-442749 https://reactome.org/PathwayBrowser/#/R-HSA-442749 CaMKK autophosphorylates in the nucleus TAS Homo sapiens 456216 R-HSA-442832 https://reactome.org/PathwayBrowser/#/R-HSA-442832 PAK phosphorylates cortactin IEA Homo sapiens 456216 R-HSA-443817 https://reactome.org/PathwayBrowser/#/R-HSA-443817 Phosphorylation of L1 by EPHB2 IEA Homo sapiens 456216 R-HSA-445072 https://reactome.org/PathwayBrowser/#/R-HSA-445072 Interaction of PAK1 with Rac1-GTP TAS Homo sapiens 456216 R-HSA-445076 https://reactome.org/PathwayBrowser/#/R-HSA-445076 Phosphorylation of Y1229 in L1 TAS Homo sapiens 456216 R-HSA-445079 https://reactome.org/PathwayBrowser/#/R-HSA-445079 Phosphorylation of L1 by ERK TAS Homo sapiens 456216 R-HSA-445084 https://reactome.org/PathwayBrowser/#/R-HSA-445084 Phosphorylation of L1 by SRC TAS Homo sapiens 456216 R-HSA-445085 https://reactome.org/PathwayBrowser/#/R-HSA-445085 Phosphorylation of VAV2 TAS Homo sapiens 456216 R-HSA-445087 https://reactome.org/PathwayBrowser/#/R-HSA-445087 CHL1 interacts with HSP7C IEA Homo sapiens 456216 R-HSA-445091 https://reactome.org/PathwayBrowser/#/R-HSA-445091 Phosphorylation of Neurofascin IEA Homo sapiens 456216 R-HSA-445699 https://reactome.org/PathwayBrowser/#/R-HSA-445699 ATP Hydrolysis By Myosin TAS Homo sapiens 456216 R-HSA-445705 https://reactome.org/PathwayBrowser/#/R-HSA-445705 Release Of ADP From Myosin TAS Homo sapiens 456216 R-HSA-445813 https://reactome.org/PathwayBrowser/#/R-HSA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains TAS Homo sapiens 456216 R-HSA-446634 https://reactome.org/PathwayBrowser/#/R-HSA-446634 IRAK4 is activated by autophosphorylation TAS Homo sapiens 456216 R-HSA-446694 https://reactome.org/PathwayBrowser/#/R-HSA-446694 IRAK4 phosphorylates IRAK1 TAS Homo sapiens 456216 R-HSA-446701 https://reactome.org/PathwayBrowser/#/R-HSA-446701 IRAK4-activated IRAK1 autophosphorylates TAS Homo sapiens 456216 R-HSA-447074 https://reactome.org/PathwayBrowser/#/R-HSA-447074 AMPK phosphorylates Raptor in the mTORC1 complex TAS Homo sapiens 456216 R-HSA-448948 https://reactome.org/PathwayBrowser/#/R-HSA-448948 Phosphorylation of E proteins by p38 MAPK IEA Homo sapiens 456216 R-HSA-448951 https://reactome.org/PathwayBrowser/#/R-HSA-448951 Activation of p38 alpha/beta MAPK IEA Homo sapiens 456216 R-HSA-448955 https://reactome.org/PathwayBrowser/#/R-HSA-448955 Phosphorylation of MEF2 proteins by p38 TAS Homo sapiens 456216 R-HSA-450222 https://reactome.org/PathwayBrowser/#/R-HSA-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 TAS Homo sapiens 456216 R-HSA-450325 https://reactome.org/PathwayBrowser/#/R-HSA-450325 c-FOS activation by phospho ERK1/2 TAS Homo sapiens 456216 R-HSA-450333 https://reactome.org/PathwayBrowser/#/R-HSA-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 TAS Homo sapiens 456216 R-HSA-450337 https://reactome.org/PathwayBrowser/#/R-HSA-450337 Activated TAK1 phosphorylates MKK4/MKK7 TAS Homo sapiens 456216 R-HSA-450346 https://reactome.org/PathwayBrowser/#/R-HSA-450346 activated human TAK1 phosphorylates MKK3/MKK6 TAS Homo sapiens 456216 R-HSA-450463 https://reactome.org/PathwayBrowser/#/R-HSA-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) TAS Homo sapiens 456216 R-HSA-450474 https://reactome.org/PathwayBrowser/#/R-HSA-450474 MK2 phosphorylates BRF1 TAS Homo sapiens 456216 R-HSA-450490 https://reactome.org/PathwayBrowser/#/R-HSA-450490 Protein Kinase B/Akt phosphorylates BRF1 TAS Homo sapiens 456216 R-HSA-450499 https://reactome.org/PathwayBrowser/#/R-HSA-450499 Protein Kinase B (AKT) phosphorylates KSRP TAS Homo sapiens 456216 R-HSA-450533 https://reactome.org/PathwayBrowser/#/R-HSA-450533 PKCdelta phosphorylates HuR TAS Homo sapiens 456216 R-HSA-450550 https://reactome.org/PathwayBrowser/#/R-HSA-450550 PKCalpha phosphorylates HuR TAS Homo sapiens 456216 R-HSA-450827 https://reactome.org/PathwayBrowser/#/R-HSA-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. TAS Homo sapiens 456216 R-HSA-451152 https://reactome.org/PathwayBrowser/#/R-HSA-451152 MAP kinase p38 phosphorylates KSRP IEA Homo sapiens 456216 R-HSA-451649 https://reactome.org/PathwayBrowser/#/R-HSA-451649 TPL2 phosphorylates MEK1, SEK1 IEA Homo sapiens 456216 R-HSA-451942 https://reactome.org/PathwayBrowser/#/R-HSA-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 TAS Homo sapiens 456216 R-HSA-452097 https://reactome.org/PathwayBrowser/#/R-HSA-452097 Recruited STAT5 is phosphorylated TAS Homo sapiens 456216 R-HSA-452100 https://reactome.org/PathwayBrowser/#/R-HSA-452100 SHC1 bound to IL2 receptor is phosphorylated TAS Homo sapiens 456216 R-HSA-452122 https://reactome.org/PathwayBrowser/#/R-HSA-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB TAS Homo sapiens 456216 R-HSA-453200 https://reactome.org/PathwayBrowser/#/R-HSA-453200 SYK autophosphorylates TAS Homo sapiens 456216 R-HSA-453337 https://reactome.org/PathwayBrowser/#/R-HSA-453337 glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP IEA Homo sapiens 456216 R-HSA-4551570 https://reactome.org/PathwayBrowser/#/R-HSA-4551570 VANGL2 is phosphorylated in response to WNT5A IEA Homo sapiens 456216 R-HSA-4608825 https://reactome.org/PathwayBrowser/#/R-HSA-4608825 DVL2 is phosphorylated after WNT5A binding to FZD TAS Homo sapiens 456216 R-HSA-4793911 https://reactome.org/PathwayBrowser/#/R-HSA-4793911 MAPKAPK2 phosphorylates HSF1 TAS Homo sapiens 456216 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 456216 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 456216 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 456216 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 456216 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 456216 R-HSA-504054 https://reactome.org/PathwayBrowser/#/R-HSA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] TAS Homo sapiens 456216 R-HSA-508040 https://reactome.org/PathwayBrowser/#/R-HSA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] TAS Homo sapiens 456216 R-HSA-5082387 https://reactome.org/PathwayBrowser/#/R-HSA-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation TAS Homo sapiens 456216 R-HSA-5082405 https://reactome.org/PathwayBrowser/#/R-HSA-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation TAS Homo sapiens 456216 R-HSA-508282 https://reactome.org/PathwayBrowser/#/R-HSA-508282 SYK is a substrate for JAK1 TAS Homo sapiens 456216 R-HSA-508308 https://reactome.org/PathwayBrowser/#/R-HSA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] TAS Homo sapiens 456216 R-HSA-5138432 https://reactome.org/PathwayBrowser/#/R-HSA-5138432 DVL2 is phosphorylated by PKC TAS Homo sapiens 456216 R-HSA-5195402 https://reactome.org/PathwayBrowser/#/R-HSA-5195402 CDK1 phosphorylates LPIN TAS Homo sapiens 456216 R-HSA-5213464 https://reactome.org/PathwayBrowser/#/R-HSA-5213464 RIPK1 is phosphorylated TAS Homo sapiens 456216 R-HSA-5213466 https://reactome.org/PathwayBrowser/#/R-HSA-5213466 RIPK3 is phosphorylated TAS Homo sapiens 456216 R-HSA-5218640 https://reactome.org/PathwayBrowser/#/R-HSA-5218640 SRC-1 phosphorylates p-Y397-PTK2 TAS Homo sapiens 456216 R-HSA-5218642 https://reactome.org/PathwayBrowser/#/R-HSA-5218642 PTK2 autophosphorylates TAS Homo sapiens 456216 R-HSA-5218804 https://reactome.org/PathwayBrowser/#/R-HSA-5218804 p38 MAPK activation by VEGFR TAS Homo sapiens 456216 R-HSA-5218805 https://reactome.org/PathwayBrowser/#/R-HSA-5218805 PKC autophosphorylates TAS Homo sapiens 456216 R-HSA-5218806 https://reactome.org/PathwayBrowser/#/R-HSA-5218806 FYN autophosphorylates TAS Homo sapiens 456216 R-HSA-5218809 https://reactome.org/PathwayBrowser/#/R-HSA-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 TAS Homo sapiens 456216 R-HSA-5218812 https://reactome.org/PathwayBrowser/#/R-HSA-5218812 FYN phosphorylates PAK2 TAS Homo sapiens 456216 R-HSA-5218814 https://reactome.org/PathwayBrowser/#/R-HSA-5218814 PAK2 autophorylates TAS Homo sapiens 456216 R-HSA-5218819 https://reactome.org/PathwayBrowser/#/R-HSA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5218820 https://reactome.org/PathwayBrowser/#/R-HSA-5218820 Src kinases phosphorylate VAV TAS Homo sapiens 456216 R-HSA-5218821 https://reactome.org/PathwayBrowser/#/R-HSA-5218821 PDK1 phosphorylates PKC TAS Homo sapiens 456216 R-HSA-5218823 https://reactome.org/PathwayBrowser/#/R-HSA-5218823 PKC phosphorylates sphingosine kinase 1 TAS Homo sapiens 456216 R-HSA-5218826 https://reactome.org/PathwayBrowser/#/R-HSA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 TAS Homo sapiens 456216 R-HSA-5218828 https://reactome.org/PathwayBrowser/#/R-HSA-5218828 PTK2/SRC-1 phosphorylates BCAR1 IEA Homo sapiens 456216 R-HSA-5218830 https://reactome.org/PathwayBrowser/#/R-HSA-5218830 SRC-1 phosphorylates PTK2-beta TAS Homo sapiens 456216 R-HSA-5218845 https://reactome.org/PathwayBrowser/#/R-HSA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate TAS Homo sapiens 456216 R-HSA-5218851 https://reactome.org/PathwayBrowser/#/R-HSA-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 TAS Homo sapiens 456216 R-HSA-5218854 https://reactome.org/PathwayBrowser/#/R-HSA-5218854 p-Y420-FYN is phosphorylated on S21 TAS Homo sapiens 456216 R-HSA-5218906 https://reactome.org/PathwayBrowser/#/R-HSA-5218906 RIPK3 phosphorylates MLKL TAS Homo sapiens 456216 R-HSA-5218916 https://reactome.org/PathwayBrowser/#/R-HSA-5218916 p-MAPK2/3 phosphorylates HSP27 TAS Homo sapiens 456216 R-HSA-5223313 https://reactome.org/PathwayBrowser/#/R-HSA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) TAS Homo sapiens 456216 R-HSA-5223317 https://reactome.org/PathwayBrowser/#/R-HSA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen TAS Homo sapiens 456216 R-HSA-5229194 https://reactome.org/PathwayBrowser/#/R-HSA-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation TAS Homo sapiens 456216 R-HSA-5229343 https://reactome.org/PathwayBrowser/#/R-HSA-5229343 AXIN is phosphorylated in the destruction complex TAS Homo sapiens 456216 R-HSA-5244669 https://reactome.org/PathwayBrowser/#/R-HSA-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments TAS Homo sapiens 456216 R-HSA-5251955 https://reactome.org/PathwayBrowser/#/R-HSA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm TAS Homo sapiens 456216 R-HSA-5251959 https://reactome.org/PathwayBrowser/#/R-HSA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol TAS Homo sapiens 456216 R-HSA-5251989 https://reactome.org/PathwayBrowser/#/R-HSA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol TAS Homo sapiens 456216 R-HSA-5252079 https://reactome.org/PathwayBrowser/#/R-HSA-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP TAS Homo sapiens 456216 R-HSA-5260201 https://reactome.org/PathwayBrowser/#/R-HSA-5260201 p-AKT2 phosphorylates C2CD5 IEA Homo sapiens 456216 R-HSA-5357429 https://reactome.org/PathwayBrowser/#/R-HSA-5357429 AXL autophosphorylates on Y779 and Y821 TAS Homo sapiens 456216 R-HSA-5357472 https://reactome.org/PathwayBrowser/#/R-HSA-5357472 PAK1-3 autophosphorylates TAS Homo sapiens 456216 R-HSA-5357477 https://reactome.org/PathwayBrowser/#/R-HSA-5357477 PAK1-3 phosphorylates VE-cadherin TAS Homo sapiens 456216 R-HSA-5357831 https://reactome.org/PathwayBrowser/#/R-HSA-5357831 CHUK, IKBKB phosphorylate CYLD at S418 TAS Homo sapiens 456216 R-HSA-5358513 https://reactome.org/PathwayBrowser/#/R-HSA-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more TAS Homo sapiens 456216 R-HSA-5358525 https://reactome.org/PathwayBrowser/#/R-HSA-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop TAS Homo sapiens 456216 R-HSA-5358912 https://reactome.org/PathwayBrowser/#/R-HSA-5358912 MSH2:MSH6 exchanges ADP for ATP TAS Homo sapiens 456216 R-HSA-5358919 https://reactome.org/PathwayBrowser/#/R-HSA-5358919 MSH2:MSH3 exchanges ADP for ATP IEA Homo sapiens 456216 R-HSA-5362459 https://reactome.org/PathwayBrowser/#/R-HSA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol TAS Homo sapiens 456216 R-HSA-5387389 https://reactome.org/PathwayBrowser/#/R-HSA-5387389 Hh processing variants are translocated to the cytosol in a VCP-dependent manner TAS Homo sapiens 456216 R-HSA-5444511 https://reactome.org/PathwayBrowser/#/R-HSA-5444511 Formation of MSH2:MSH3 Complex TAS Homo sapiens 456216 R-HSA-5444516 https://reactome.org/PathwayBrowser/#/R-HSA-5444516 Formation of MSH2:MSH6 Complex TAS Homo sapiens 456216 R-HSA-5578777 https://reactome.org/PathwayBrowser/#/R-HSA-5578777 DMPK phosphorylates PLN TAS Homo sapiens 456216 R-HSA-5607722 https://reactome.org/PathwayBrowser/#/R-HSA-5607722 Active NIK phosphorylates IKKA dimer TAS Homo sapiens 456216 R-HSA-5607726 https://reactome.org/PathwayBrowser/#/R-HSA-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB TAS Homo sapiens 456216 R-HSA-5607732 https://reactome.org/PathwayBrowser/#/R-HSA-5607732 K63polyUb-TAK1 autophosphorylates TAS Homo sapiens 456216 R-HSA-5607740 https://reactome.org/PathwayBrowser/#/R-HSA-5607740 PKC-delta phosphorylates CARD9 TAS Homo sapiens 456216 R-HSA-5607742 https://reactome.org/PathwayBrowser/#/R-HSA-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta TAS Homo sapiens 456216 R-HSA-5607745 https://reactome.org/PathwayBrowser/#/R-HSA-5607745 1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG IEA Homo sapiens 456216 R-HSA-5607750 https://reactome.org/PathwayBrowser/#/R-HSA-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan TAS Homo sapiens 456216 R-HSA-5610717 https://reactome.org/PathwayBrowser/#/R-HSA-5610717 PKA phosphorylates GLI2 IEA Homo sapiens 456216 R-HSA-5610718 https://reactome.org/PathwayBrowser/#/R-HSA-5610718 CK1 phosphorylates p-GLI2 IEA Homo sapiens 456216 R-HSA-5610720 https://reactome.org/PathwayBrowser/#/R-HSA-5610720 PKA phosphorylates GLI3 TAS Homo sapiens 456216 R-HSA-5610722 https://reactome.org/PathwayBrowser/#/R-HSA-5610722 CK1 phosphorylates p-GLI3 TAS Homo sapiens 456216 R-HSA-5610730 https://reactome.org/PathwayBrowser/#/R-HSA-5610730 GSK3 phosphorylates p-GLI2 IEA Homo sapiens 456216 R-HSA-5610732 https://reactome.org/PathwayBrowser/#/R-HSA-5610732 GSK3 phosphorylates p-GLI3 TAS Homo sapiens 456216 R-HSA-5610741 https://reactome.org/PathwayBrowser/#/R-HSA-5610741 PKA phosphorylates GLI1 IEA Homo sapiens 456216 R-HSA-5617179 https://reactome.org/PathwayBrowser/#/R-HSA-5617179 PRKACA phosphorylates TNNI3 TAS Homo sapiens 456216 R-HSA-5617182 https://reactome.org/PathwayBrowser/#/R-HSA-5617182 PRKACA phosphorylates PLN TAS Homo sapiens 456216 R-HSA-5618085 https://reactome.org/PathwayBrowser/#/R-HSA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein TAS Homo sapiens 456216 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 456216 R-HSA-5618098 https://reactome.org/PathwayBrowser/#/R-HSA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein TAS Homo sapiens 456216 R-HSA-5618105 https://reactome.org/PathwayBrowser/#/R-HSA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein TAS Homo sapiens 456216 R-HSA-5618107 https://reactome.org/PathwayBrowser/#/R-HSA-5618107 ATP binding to HSP90 triggers conformation change TAS Homo sapiens 456216 R-HSA-5618110 https://reactome.org/PathwayBrowser/#/R-HSA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein TAS Homo sapiens 456216 R-HSA-5621355 https://reactome.org/PathwayBrowser/#/R-HSA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG TAS Homo sapiens 456216 R-HSA-5621363 https://reactome.org/PathwayBrowser/#/R-HSA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 TAS Homo sapiens 456216 R-HSA-5621370 https://reactome.org/PathwayBrowser/#/R-HSA-5621370 SYK autophosphorylates TAS Homo sapiens 456216 R-HSA-5623667 https://reactome.org/PathwayBrowser/#/R-HSA-5623667 PDPK1 phosphorylates PKN1,2,3 TAS Homo sapiens 456216 R-HSA-5624473 https://reactome.org/PathwayBrowser/#/R-HSA-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit TAS Homo sapiens 456216 R-HSA-5624486 https://reactome.org/PathwayBrowser/#/R-HSA-5624486 SFKs phosphorylates RAF1 on Y340,Y341 TAS Homo sapiens 456216 R-HSA-5624492 https://reactome.org/PathwayBrowser/#/R-HSA-5624492 PAK phosphorylates p21 RAF1 on S338 TAS Homo sapiens 456216 R-HSA-5625784 https://reactome.org/PathwayBrowser/#/R-HSA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters TAS Homo sapiens 456216 R-HSA-5627775 https://reactome.org/PathwayBrowser/#/R-HSA-5627775 Autophosphorylation of PAK1,2,3 TAS Homo sapiens 456216 R-HSA-5632670 https://reactome.org/PathwayBrowser/#/R-HSA-5632670 CSNK1A1 phosphorylates SMO dimer IEA Homo sapiens 456216 R-HSA-5632672 https://reactome.org/PathwayBrowser/#/R-HSA-5632672 ADRBK1 phosphorylates SMO dimer IEA Homo sapiens 456216 R-HSA-5635841 https://reactome.org/PathwayBrowser/#/R-HSA-5635841 GLI proteins are phosphorylated TAS Homo sapiens 456216 R-HSA-5635842 https://reactome.org/PathwayBrowser/#/R-HSA-5635842 ULK3 phosphorylates GLI TAS Homo sapiens 456216 R-HSA-5637795 https://reactome.org/PathwayBrowser/#/R-HSA-5637795 Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant TAS Homo sapiens 456216 R-HSA-5637796 https://reactome.org/PathwayBrowser/#/R-HSA-5637796 Phosphorylation of SHC1 by p-5Y-EGFRvIII TAS Homo sapiens 456216 R-HSA-5637801 https://reactome.org/PathwayBrowser/#/R-HSA-5637801 Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII TAS Homo sapiens 456216 R-HSA-5654147 https://reactome.org/PathwayBrowser/#/R-HSA-5654147 Activated FGFR2 phosphorylates PLCG1 TAS Homo sapiens 456216 R-HSA-5654149 https://reactome.org/PathwayBrowser/#/R-HSA-5654149 Activated FGFR1 phosphorylates PLCG1 TAS Homo sapiens 456216 R-HSA-5654151 https://reactome.org/PathwayBrowser/#/R-HSA-5654151 Activated FGFR4 phosphorylates PLCG1 TAS Homo sapiens 456216 R-HSA-5654222 https://reactome.org/PathwayBrowser/#/R-HSA-5654222 Activated FGFR3 phosphorylates PLCG1 TAS Homo sapiens 456216 R-HSA-5654397 https://reactome.org/PathwayBrowser/#/R-HSA-5654397 Activated FGFR2 phosphorylates FRS2 TAS Homo sapiens 456216 R-HSA-5654407 https://reactome.org/PathwayBrowser/#/R-HSA-5654407 Activated FGFR2 phosphorylates SHC1 TAS Homo sapiens 456216 R-HSA-5654408 https://reactome.org/PathwayBrowser/#/R-HSA-5654408 Activated FGFR3 phosphorylates FRS2 TAS Homo sapiens 456216 R-HSA-5654418 https://reactome.org/PathwayBrowser/#/R-HSA-5654418 Activated FGFR4 phosphorylates FRS2 TAS Homo sapiens 456216 R-HSA-5654428 https://reactome.org/PathwayBrowser/#/R-HSA-5654428 Activated FGFR4 phosphorylates SHC1 TAS Homo sapiens 456216 R-HSA-5654545 https://reactome.org/PathwayBrowser/#/R-HSA-5654545 Ligand-independent phosphorylation of overexpressed FGFR1c TAS Homo sapiens 456216 R-HSA-5654560 https://reactome.org/PathwayBrowser/#/R-HSA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. TAS Homo sapiens 456216 R-HSA-5654562 https://reactome.org/PathwayBrowser/#/R-HSA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 TAS Homo sapiens 456216 R-HSA-5654565 https://reactome.org/PathwayBrowser/#/R-HSA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. TAS Homo sapiens 456216 R-HSA-5654566 https://reactome.org/PathwayBrowser/#/R-HSA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. TAS Homo sapiens 456216 R-HSA-5654575 https://reactome.org/PathwayBrowser/#/R-HSA-5654575 Activated FGFR1 phosphorylates FRS2 TAS Homo sapiens 456216 R-HSA-5654578 https://reactome.org/PathwayBrowser/#/R-HSA-5654578 Activated FGFR1 phosphorylates FRS3 TAS Homo sapiens 456216 R-HSA-5654582 https://reactome.org/PathwayBrowser/#/R-HSA-5654582 Activated FGFR1 phosphorylates SHC1 TAS Homo sapiens 456216 R-HSA-5654587 https://reactome.org/PathwayBrowser/#/R-HSA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 TAS Homo sapiens 456216 R-HSA-5654605 https://reactome.org/PathwayBrowser/#/R-HSA-5654605 Activated FGFR2 phosphorylates FRS3 TAS Homo sapiens 456216 R-HSA-5654607 https://reactome.org/PathwayBrowser/#/R-HSA-5654607 Activated FGFR2 phosphorylates PPTN11 TAS Homo sapiens 456216 R-HSA-5654628 https://reactome.org/PathwayBrowser/#/R-HSA-5654628 Activated FGFR3 phosphorylates FRS3 TAS Homo sapiens 456216 R-HSA-5654631 https://reactome.org/PathwayBrowser/#/R-HSA-5654631 Activated FGFR3 phosphorylates PPTN11 TAS Homo sapiens 456216 R-HSA-5654634 https://reactome.org/PathwayBrowser/#/R-HSA-5654634 Activated FGFR3 phosphorylates SHC1 TAS Homo sapiens 456216 R-HSA-5654653 https://reactome.org/PathwayBrowser/#/R-HSA-5654653 Activated FGFR4 phosphorylates FRS3 TAS Homo sapiens 456216 R-HSA-5654655 https://reactome.org/PathwayBrowser/#/R-HSA-5654655 Activated FGFR4 phosphorylates PPTN11 TAS Homo sapiens 456216 R-HSA-5654690 https://reactome.org/PathwayBrowser/#/R-HSA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5654692 https://reactome.org/PathwayBrowser/#/R-HSA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5654697 https://reactome.org/PathwayBrowser/#/R-HSA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5654701 https://reactome.org/PathwayBrowser/#/R-HSA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5654705 https://reactome.org/PathwayBrowser/#/R-HSA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5654709 https://reactome.org/PathwayBrowser/#/R-HSA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5654714 https://reactome.org/PathwayBrowser/#/R-HSA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5654717 https://reactome.org/PathwayBrowser/#/R-HSA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5654989 https://reactome.org/PathwayBrowser/#/R-HSA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA TAS Homo sapiens 456216 R-HSA-5655235 https://reactome.org/PathwayBrowser/#/R-HSA-5655235 Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5655243 https://reactome.org/PathwayBrowser/#/R-HSA-5655243 Activated FGFR3 point and translocation mutants phosphorylate PLCG1 TAS Homo sapiens 456216 R-HSA-5655268 https://reactome.org/PathwayBrowser/#/R-HSA-5655268 Activated FGFR2 mutants phosphorylate FRS2 TAS Homo sapiens 456216 R-HSA-5655270 https://reactome.org/PathwayBrowser/#/R-HSA-5655270 Activated FGFR3 point, translocation and fusion mutants phosphorylate FRS2 TAS Homo sapiens 456216 R-HSA-5655278 https://reactome.org/PathwayBrowser/#/R-HSA-5655278 Activated FGFR1 mutants phosphorylate FRS2 TAS Homo sapiens 456216 R-HSA-5655284 https://reactome.org/PathwayBrowser/#/R-HSA-5655284 Activated FGFR4 mutants phosphorylate FRS2 TAS Homo sapiens 456216 R-HSA-5655289 https://reactome.org/PathwayBrowser/#/R-HSA-5655289 Activated FGFR3 point, translocation and fusion mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5655290 https://reactome.org/PathwayBrowser/#/R-HSA-5655290 Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5655301 https://reactome.org/PathwayBrowser/#/R-HSA-5655301 Activated FGFR2 mutants phosphorylate PLCG1 TAS Homo sapiens 456216 R-HSA-5655323 https://reactome.org/PathwayBrowser/#/R-HSA-5655323 Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-5655341 https://reactome.org/PathwayBrowser/#/R-HSA-5655341 Activated FGFR4 mutants phosphorylate PLCG1 TAS Homo sapiens 456216 R-HSA-5662466 https://reactome.org/PathwayBrowser/#/R-HSA-5662466 XYLB phosphorylates D-xylulose TAS Homo sapiens 456216 R-HSA-5665868 https://reactome.org/PathwayBrowser/#/R-HSA-5665868 AMPK (complex) phosphorylates ULK1 (complex) TAS Homo sapiens 456216 R-HSA-5666160 https://reactome.org/PathwayBrowser/#/R-HSA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores TAS Homo sapiens 456216 R-HSA-5668545 https://reactome.org/PathwayBrowser/#/R-HSA-5668545 NIK autophosphorylates on T559 TAS Homo sapiens 456216 R-HSA-5668932 https://reactome.org/PathwayBrowser/#/R-HSA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) TAS Homo sapiens 456216 R-HSA-5668947 https://reactome.org/PathwayBrowser/#/R-HSA-5668947 PAK1 phosphorylates myosin phosphatase TAS Homo sapiens 456216 R-HSA-5668978 https://reactome.org/PathwayBrowser/#/R-HSA-5668978 MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex IEA Homo sapiens 456216 R-HSA-5668984 https://reactome.org/PathwayBrowser/#/R-HSA-5668984 PAK1 or PAK2 phosphorylates MYLK TAS Homo sapiens 456216 R-HSA-5669250 https://reactome.org/PathwayBrowser/#/R-HSA-5669250 PAK1 phosphorylates FLNA TAS Homo sapiens 456216 R-HSA-5671749 https://reactome.org/PathwayBrowser/#/R-HSA-5671749 p-T774-PKN1 phosphorylates CDC25C TAS Homo sapiens 456216 R-HSA-5671763 https://reactome.org/PathwayBrowser/#/R-HSA-5671763 p-T774-PKN1 phosphorylates PPP1R14A TAS Homo sapiens 456216 R-HSA-5671919 https://reactome.org/PathwayBrowser/#/R-HSA-5671919 Activated CIT phosphorylates MRLCs IEA Homo sapiens 456216 R-HSA-5672008 https://reactome.org/PathwayBrowser/#/R-HSA-5672008 Thr-180 of ULK1 is phosphorylated TAS Homo sapiens 456216 R-HSA-5672010 https://reactome.org/PathwayBrowser/#/R-HSA-5672010 Active MTORC1 phosphorylates ULK1 TAS Homo sapiens 456216 R-HSA-5672012 https://reactome.org/PathwayBrowser/#/R-HSA-5672012 Beclin-1 complex phosphorylates PtdIns TAS Homo sapiens 456216 R-HSA-5672027 https://reactome.org/PathwayBrowser/#/R-HSA-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane TAS Homo sapiens 456216 R-HSA-5672828 https://reactome.org/PathwayBrowser/#/R-HSA-5672828 mTORC1 phosphorylates AKT1S1 TAS Homo sapiens 456216 R-HSA-5672948 https://reactome.org/PathwayBrowser/#/R-HSA-5672948 MARK3 phosphorylates KSR1 TAS Homo sapiens 456216 R-HSA-5672969 https://reactome.org/PathwayBrowser/#/R-HSA-5672969 Phosphorylation of RAF TAS Homo sapiens 456216 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 456216 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 456216 R-HSA-5673768 https://reactome.org/PathwayBrowser/#/R-HSA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex TAS Homo sapiens 456216 R-HSA-5674130 https://reactome.org/PathwayBrowser/#/R-HSA-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane TAS Homo sapiens 456216 R-HSA-5674373 https://reactome.org/PathwayBrowser/#/R-HSA-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane TAS Homo sapiens 456216 R-HSA-5674496 https://reactome.org/PathwayBrowser/#/R-HSA-5674496 Activated MAPKs phosphorylate MAP2K1 TAS Homo sapiens 456216 R-HSA-5675194 https://reactome.org/PathwayBrowser/#/R-HSA-5675194 Activated MAPK phosphorylates RAF1 TAS Homo sapiens 456216 R-HSA-5675198 https://reactome.org/PathwayBrowser/#/R-HSA-5675198 Activated MAPKs phosphorylate BRAF TAS Homo sapiens 456216 R-HSA-5675868 https://reactome.org/PathwayBrowser/#/R-HSA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 TAS Homo sapiens 456216 R-HSA-5678706 https://reactome.org/PathwayBrowser/#/R-HSA-5678706 ABCB4 transports PC from plasma membrane to extracellular region TAS Homo sapiens 456216 R-HSA-5678863 https://reactome.org/PathwayBrowser/#/R-HSA-5678863 CFTR transports Cl- from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-5678992 https://reactome.org/PathwayBrowser/#/R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-5679041 https://reactome.org/PathwayBrowser/#/R-HSA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-5679205 https://reactome.org/PathwayBrowser/#/R-HSA-5679205 ULK1 phosphorylates Beclin-1 TAS Homo sapiens 456216 R-HSA-5682026 https://reactome.org/PathwayBrowser/#/R-HSA-5682026 MRN bound to shortened telomeres activates ATM TAS Homo sapiens 456216 R-HSA-5682101 https://reactome.org/PathwayBrowser/#/R-HSA-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer TAS Homo sapiens 456216 R-HSA-5682285 https://reactome.org/PathwayBrowser/#/R-HSA-5682285 ABCA12 transports lipids from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-5682598 https://reactome.org/PathwayBrowser/#/R-HSA-5682598 ATM phosphorylates HERC2 TAS Homo sapiens 456216 R-HSA-5682983 https://reactome.org/PathwayBrowser/#/R-HSA-5682983 ATM phosphorylates WHSC1 TAS Homo sapiens 456216 R-HSA-5683425 https://reactome.org/PathwayBrowser/#/R-HSA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs TAS Homo sapiens 456216 R-HSA-5683714 https://reactome.org/PathwayBrowser/#/R-HSA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body TAS Homo sapiens 456216 R-HSA-5683792 https://reactome.org/PathwayBrowser/#/R-HSA-5683792 p-T68-CHEK2 autophosphorylates TAS Homo sapiens 456216 R-HSA-5683801 https://reactome.org/PathwayBrowser/#/R-HSA-5683801 CHEK2 phosphorylates BRCA1 TAS Homo sapiens 456216 R-HSA-5683930 https://reactome.org/PathwayBrowser/#/R-HSA-5683930 WICH phosphorylates H2AFX on Y142 TAS Homo sapiens 456216 R-HSA-5683964 https://reactome.org/PathwayBrowser/#/R-HSA-5683964 ATM phosphorylates EYA1-4 TAS Homo sapiens 456216 R-HSA-5684096 https://reactome.org/PathwayBrowser/#/R-HSA-5684096 CDK2 phosphorylates RBBP8 TAS Homo sapiens 456216 R-HSA-5684140 https://reactome.org/PathwayBrowser/#/R-HSA-5684140 ATM phosphorylates RBBP8 TAS Homo sapiens 456216 R-HSA-5684261 https://reactome.org/PathwayBrowser/#/R-HSA-5684261 MAP3K8 is phosphorylated TAS Homo sapiens 456216 R-HSA-5684267 https://reactome.org/PathwayBrowser/#/R-HSA-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex TAS Homo sapiens 456216 R-HSA-5684275 https://reactome.org/PathwayBrowser/#/R-HSA-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 TAS Homo sapiens 456216 R-HSA-5684806 https://reactome.org/PathwayBrowser/#/R-HSA-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN TAS Homo sapiens 456216 R-HSA-5684887 https://reactome.org/PathwayBrowser/#/R-HSA-5684887 Activation of CHEK1 at resected DNA DSBs TAS Homo sapiens 456216 R-HSA-5685156 https://reactome.org/PathwayBrowser/#/R-HSA-5685156 ATR phosphorylates RPA2 TAS Homo sapiens 456216 R-HSA-5685230 https://reactome.org/PathwayBrowser/#/R-HSA-5685230 CHEK1 phosphorylates RAD51 TAS Homo sapiens 456216 R-HSA-5685242 https://reactome.org/PathwayBrowser/#/R-HSA-5685242 CHEK1 phosphorylates BRCA2 TAS Homo sapiens 456216 R-HSA-5686410 https://reactome.org/PathwayBrowser/#/R-HSA-5686410 BLM mediates dissolution of double Holliday junction TAS Homo sapiens 456216 R-HSA-5686578 https://reactome.org/PathwayBrowser/#/R-HSA-5686578 Activated ATM phosphorylates ABL1 TAS Homo sapiens 456216 R-HSA-5686587 https://reactome.org/PathwayBrowser/#/R-HSA-5686587 ABL1 phosphorylates RAD52 TAS Homo sapiens 456216 R-HSA-5686704 https://reactome.org/PathwayBrowser/#/R-HSA-5686704 Activated ATM phosphorylates DCLRE1C TAS Homo sapiens 456216 R-HSA-5687086 https://reactome.org/PathwayBrowser/#/R-HSA-5687086 PAK1,2,3 phosphorylates MAPK6,4 TAS Homo sapiens 456216 R-HSA-5687088 https://reactome.org/PathwayBrowser/#/R-HSA-5687088 PKA phosphorylates MAPKAPK5 TAS Homo sapiens 456216 R-HSA-5687090 https://reactome.org/PathwayBrowser/#/R-HSA-5687090 p-S MAPK6 phosphorylates NCOA3 TAS Homo sapiens 456216 R-HSA-5687094 https://reactome.org/PathwayBrowser/#/R-HSA-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 TAS Homo sapiens 456216 R-HSA-5687101 https://reactome.org/PathwayBrowser/#/R-HSA-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 TAS Homo sapiens 456216 R-HSA-5687121 https://reactome.org/PathwayBrowser/#/R-HSA-5687121 p-S MAPKAPK5 phosphorylates HSPB1 TAS Homo sapiens 456216 R-HSA-5687183 https://reactome.org/PathwayBrowser/#/R-HSA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs TAS Homo sapiens 456216 R-HSA-5690250 https://reactome.org/PathwayBrowser/#/R-HSA-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 TAS Homo sapiens 456216 R-HSA-5690702 https://reactome.org/PathwayBrowser/#/R-HSA-5690702 LYN phosphorylates CD22 TAS Homo sapiens 456216 R-HSA-5690996 https://reactome.org/PathwayBrowser/#/R-HSA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA TAS Homo sapiens 456216 R-HSA-5692462 https://reactome.org/PathwayBrowser/#/R-HSA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen TAS Homo sapiens 456216 R-HSA-5692480 https://reactome.org/PathwayBrowser/#/R-HSA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen TAS Homo sapiens 456216 R-HSA-5692755 https://reactome.org/PathwayBrowser/#/R-HSA-5692755 CDK1 phosphorylates MAPK6 TAS Homo sapiens 456216 R-HSA-5692768 https://reactome.org/PathwayBrowser/#/R-HSA-5692768 MAPKAPK5 phosphorylates KALRN TAS Homo sapiens 456216 R-HSA-5692775 https://reactome.org/PathwayBrowser/#/R-HSA-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs TAS Homo sapiens 456216 R-HSA-5692779 https://reactome.org/PathwayBrowser/#/R-HSA-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 TAS Homo sapiens 456216 R-HSA-5693148 https://reactome.org/PathwayBrowser/#/R-HSA-5693148 BCKDK phosphorylates BCKDH TAS Homo sapiens 456216 R-HSA-5693536 https://reactome.org/PathwayBrowser/#/R-HSA-5693536 ATM phosphorylates MDC1 TAS Homo sapiens 456216 R-HSA-5693540 https://reactome.org/PathwayBrowser/#/R-HSA-5693540 MRN activates ATM TAS Homo sapiens 456216 R-HSA-5693549 https://reactome.org/PathwayBrowser/#/R-HSA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs TAS Homo sapiens 456216 R-HSA-5693551 https://reactome.org/PathwayBrowser/#/R-HSA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM TAS Homo sapiens 456216 R-HSA-5693575 https://reactome.org/PathwayBrowser/#/R-HSA-5693575 DNA-PKcs autophosphorylates TAS Homo sapiens 456216 R-HSA-5693589 https://reactome.org/PathwayBrowser/#/R-HSA-5693589 D-loop dissociation and strand annealing TAS Homo sapiens 456216 R-HSA-5693598 https://reactome.org/PathwayBrowser/#/R-HSA-5693598 ATM phosphorylates NBN TAS Homo sapiens 456216 R-HSA-5693609 https://reactome.org/PathwayBrowser/#/R-HSA-5693609 ATM phosphorylates TP53 at S15 TAS Homo sapiens 456216 R-HSA-5694441 https://reactome.org/PathwayBrowser/#/R-HSA-5694441 CSNK1D phosphorylates SEC23 TAS Homo sapiens 456216 R-HSA-5696021 https://reactome.org/PathwayBrowser/#/R-HSA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P TAS Homo sapiens 456216 R-HSA-5696074 https://reactome.org/PathwayBrowser/#/R-HSA-5696074 AGK:Mg2+ phosphorylates MAG, DAG TAS Homo sapiens 456216 R-HSA-5696839 https://reactome.org/PathwayBrowser/#/R-HSA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF TAS Homo sapiens 456216 R-HSA-593690 https://reactome.org/PathwayBrowser/#/R-HSA-593690 Phosphorylation of PLCgamma by Netrin-1 IEA Homo sapiens 456216 R-HSA-6782131 https://reactome.org/PathwayBrowser/#/R-HSA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER TAS Homo sapiens 456216 R-HSA-6784006 https://reactome.org/PathwayBrowser/#/R-HSA-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 TAS Homo sapiens 456216 R-HSA-6784319 https://reactome.org/PathwayBrowser/#/R-HSA-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 TAS Homo sapiens 456216 R-HSA-6784324 https://reactome.org/PathwayBrowser/#/R-HSA-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA TAS Homo sapiens 456216 R-HSA-6786050 https://reactome.org/PathwayBrowser/#/R-HSA-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated TAS Homo sapiens 456216 R-HSA-6786095 https://reactome.org/PathwayBrowser/#/R-HSA-6786095 JAK1 phosphorylates STAT3,STAT6 TAS Homo sapiens 456216 R-HSA-6786096 https://reactome.org/PathwayBrowser/#/R-HSA-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated TAS Homo sapiens 456216 R-HSA-6786245 https://reactome.org/PathwayBrowser/#/R-HSA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN TAS Homo sapiens 456216 R-HSA-6787540 https://reactome.org/PathwayBrowser/#/R-HSA-6787540 FUK phosphorylates beta-Fuc to Fuc1P TAS Homo sapiens 456216 R-HSA-6788392 https://reactome.org/PathwayBrowser/#/R-HSA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA TAS Homo sapiens 456216 R-HSA-6788582 https://reactome.org/PathwayBrowser/#/R-HSA-6788582 STAT1,STAT3,STAT6 phosphorylation TAS Homo sapiens 456216 R-HSA-6788798 https://reactome.org/PathwayBrowser/#/R-HSA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 456216 R-HSA-6788810 https://reactome.org/PathwayBrowser/#/R-HSA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 456216 R-HSA-6788855 https://reactome.org/PathwayBrowser/#/R-HSA-6788855 FN3KRP phosphorylates PsiAm, RibAm TAS Homo sapiens 456216 R-HSA-6788867 https://reactome.org/PathwayBrowser/#/R-HSA-6788867 FN3K phosphorylates ketosamines TAS Homo sapiens 456216 R-HSA-6790087 https://reactome.org/PathwayBrowser/#/R-HSA-6790087 HVEM induses BTLA phosphorylation IEA Homo sapiens 456216 R-HSA-6790987 https://reactome.org/PathwayBrowser/#/R-HSA-6790987 NAT10 acetylates cytidine-1337 and cytidine-1842 of 18S rRNA yielding 4-acetylcytidine-1377 and 4-acetylcytidine-1842 TAS Homo sapiens 456216 R-HSA-6793661 https://reactome.org/PathwayBrowser/#/R-HSA-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 TAS Homo sapiens 456216 R-HSA-6795290 https://reactome.org/PathwayBrowser/#/R-HSA-6795290 TORC2 complex phosphorylates SGK1 TAS Homo sapiens 456216 R-HSA-6795460 https://reactome.org/PathwayBrowser/#/R-HSA-6795460 SGK1 phosphorylates MDM2 TAS Homo sapiens 456216 R-HSA-6795473 https://reactome.org/PathwayBrowser/#/R-HSA-6795473 PDPK1 phosphorylates SGK1 TAS Homo sapiens 456216 R-HSA-6797606 https://reactome.org/PathwayBrowser/#/R-HSA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes TAS Homo sapiens 456216 R-HSA-6798174 https://reactome.org/PathwayBrowser/#/R-HSA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P TAS Homo sapiens 456216 R-HSA-6798372 https://reactome.org/PathwayBrowser/#/R-HSA-6798372 ATM phosphorylates DYRK2 TAS Homo sapiens 456216 R-HSA-6798374 https://reactome.org/PathwayBrowser/#/R-HSA-6798374 DYRK2 phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6799097 https://reactome.org/PathwayBrowser/#/R-HSA-6799097 ATM phosphorylates ZNF420 TAS Homo sapiens 456216 R-HSA-6799246 https://reactome.org/PathwayBrowser/#/R-HSA-6799246 CHEK1 phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6799332 https://reactome.org/PathwayBrowser/#/R-HSA-6799332 ATR phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6799409 https://reactome.org/PathwayBrowser/#/R-HSA-6799409 HIPK2 phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6799495 https://reactome.org/PathwayBrowser/#/R-HSA-6799495 GLYCTK phosphorylates DGA to 3PDGA TAS Homo sapiens 456216 R-HSA-6800490 https://reactome.org/PathwayBrowser/#/R-HSA-6800490 ATM phosphorylates PIDD1 TAS Homo sapiens 456216 R-HSA-6801342 https://reactome.org/PathwayBrowser/#/R-HSA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG TAS Homo sapiens 456216 R-HSA-6801456 https://reactome.org/PathwayBrowser/#/R-HSA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF TAS Homo sapiens 456216 R-HSA-6801666 https://reactome.org/PathwayBrowser/#/R-HSA-6801666 PLK2 phosphorylates CENPJ TAS Homo sapiens 456216 R-HSA-6801675 https://reactome.org/PathwayBrowser/#/R-HSA-6801675 PLK2 phosphorylates NPM1 TAS Homo sapiens 456216 R-HSA-6802910 https://reactome.org/PathwayBrowser/#/R-HSA-6802910 Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants TAS Homo sapiens 456216 R-HSA-6802911 https://reactome.org/PathwayBrowser/#/R-HSA-6802911 High kinase activity BRAF complexes phosphorylate MAP2Ks TAS Homo sapiens 456216 R-HSA-6802916 https://reactome.org/PathwayBrowser/#/R-HSA-6802916 RAF is phosphorylated downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 456216 R-HSA-6802918 https://reactome.org/PathwayBrowser/#/R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants TAS Homo sapiens 456216 R-HSA-6802919 https://reactome.org/PathwayBrowser/#/R-HSA-6802919 RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 456216 R-HSA-6802921 https://reactome.org/PathwayBrowser/#/R-HSA-6802921 Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 456216 R-HSA-6802922 https://reactome.org/PathwayBrowser/#/R-HSA-6802922 Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS TAS Homo sapiens 456216 R-HSA-6802924 https://reactome.org/PathwayBrowser/#/R-HSA-6802924 RAF is phosphorylated downstream of oncogenic RAS TAS Homo sapiens 456216 R-HSA-6802926 https://reactome.org/PathwayBrowser/#/R-HSA-6802926 Mutant RAS:p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 456216 R-HSA-6802927 https://reactome.org/PathwayBrowser/#/R-HSA-6802927 BRAF and RAF fusion mutant dimers are phosphorylated TAS Homo sapiens 456216 R-HSA-6802933 https://reactome.org/PathwayBrowser/#/R-HSA-6802933 p-BRAF and RAF fusion dimers phosphorylate MAP2Ks TAS Homo sapiens 456216 R-HSA-6802935 https://reactome.org/PathwayBrowser/#/R-HSA-6802935 MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers TAS Homo sapiens 456216 R-HSA-6802941 https://reactome.org/PathwayBrowser/#/R-HSA-6802941 RAF is paradoxically phosphorylated downstream of kinase-inactive RAF TAS Homo sapiens 456216 R-HSA-6802943 https://reactome.org/PathwayBrowser/#/R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 456216 R-HSA-6802973 https://reactome.org/PathwayBrowser/#/R-HSA-6802973 PLK3 phosphorylates CDC25C TAS Homo sapiens 456216 R-HSA-6803545 https://reactome.org/PathwayBrowser/#/R-HSA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen TAS Homo sapiens 456216 R-HSA-6803771 https://reactome.org/PathwayBrowser/#/R-HSA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P TAS Homo sapiens 456216 R-HSA-6804266 https://reactome.org/PathwayBrowser/#/R-HSA-6804266 CHEK2 phosphorylates TTC5 TAS Homo sapiens 456216 R-HSA-6804276 https://reactome.org/PathwayBrowser/#/R-HSA-6804276 ATM phosphorylates TTC5 TAS Homo sapiens 456216 R-HSA-6804955 https://reactome.org/PathwayBrowser/#/R-HSA-6804955 ATM phosphorylates MDM2 TAS Homo sapiens 456216 R-HSA-6805059 https://reactome.org/PathwayBrowser/#/R-HSA-6805059 CK2:FACT phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6805103 https://reactome.org/PathwayBrowser/#/R-HSA-6805103 AURKA phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6805109 https://reactome.org/PathwayBrowser/#/R-HSA-6805109 CDK2 phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6805126 https://reactome.org/PathwayBrowser/#/R-HSA-6805126 AURKB phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6805276 https://reactome.org/PathwayBrowser/#/R-HSA-6805276 CDK5 phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6805285 https://reactome.org/PathwayBrowser/#/R-HSA-6805285 PLK3 phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6805399 https://reactome.org/PathwayBrowser/#/R-HSA-6805399 TAF1 phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6805470 https://reactome.org/PathwayBrowser/#/R-HSA-6805470 AMPK phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6805479 https://reactome.org/PathwayBrowser/#/R-HSA-6805479 TP53RK phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-6805507 https://reactome.org/PathwayBrowser/#/R-HSA-6805507 APAF1 binds AVEN TAS Homo sapiens 456216 R-HSA-6805640 https://reactome.org/PathwayBrowser/#/R-HSA-6805640 AKT phosphorylates KAT6A TAS Homo sapiens 456216 R-HSA-6805785 https://reactome.org/PathwayBrowser/#/R-HSA-6805785 AKT phosphorylates PHF20 TAS Homo sapiens 456216 R-HSA-6806877 https://reactome.org/PathwayBrowser/#/R-HSA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs TAS Homo sapiens 456216 R-HSA-6806967 https://reactome.org/PathwayBrowser/#/R-HSA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH TAS Homo sapiens 456216 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 456216 R-HSA-6807868 https://reactome.org/PathwayBrowser/#/R-HSA-6807868 GBF1 stimulates ARF nucleotide exchange TAS Homo sapiens 456216 R-HSA-6810233 https://reactome.org/PathwayBrowser/#/R-HSA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter TAS Homo sapiens 456216 R-HSA-6810472 https://reactome.org/PathwayBrowser/#/R-HSA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP TAS Homo sapiens 456216 R-HSA-6811454 https://reactome.org/PathwayBrowser/#/R-HSA-6811454 MAPKs phosphorylate PP2A TAS Homo sapiens 456216 R-HSA-6811522 https://reactome.org/PathwayBrowser/#/R-HSA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus TAS Homo sapiens 456216 R-HSA-6814119 https://reactome.org/PathwayBrowser/#/R-HSA-6814119 TRiC/CCT binds unfolded G-protein beta subunit TAS Homo sapiens 456216 R-HSA-6814120 https://reactome.org/PathwayBrowser/#/R-HSA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT TAS Homo sapiens 456216 R-HSA-6814121 https://reactome.org/PathwayBrowser/#/R-HSA-6814121 PDCL binds G-protein beta and TRiC/CCT TAS Homo sapiens 456216 R-HSA-6814124 https://reactome.org/PathwayBrowser/#/R-HSA-6814124 ATP binds G-protein beta associated TRiC/CCT TAS Homo sapiens 456216 R-HSA-6814409 https://reactome.org/PathwayBrowser/#/R-HSA-6814409 CK2 phosphorylates PDCL TAS Homo sapiens 456216 R-HSA-6814670 https://reactome.org/PathwayBrowser/#/R-HSA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation TAS Homo sapiens 456216 R-HSA-6814678 https://reactome.org/PathwayBrowser/#/R-HSA-6814678 ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN TAS Homo sapiens 456216 R-HSA-6814683 https://reactome.org/PathwayBrowser/#/R-HSA-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN TAS Homo sapiens 456216 R-HSA-68944 https://reactome.org/PathwayBrowser/#/R-HSA-68944 Orc1 is phosphorylated by cyclin A/CDK2 TAS Homo sapiens 456216 R-HSA-68954 https://reactome.org/PathwayBrowser/#/R-HSA-68954 Mcm2-7 is phosphorylated by DDK TAS Homo sapiens 456216 R-HSA-69005 https://reactome.org/PathwayBrowser/#/R-HSA-69005 Cdc6 protein is phosphorylated by CDK TAS Homo sapiens 456216 R-HSA-69063 https://reactome.org/PathwayBrowser/#/R-HSA-69063 Loading of PCNA - Sliding Clamp Formation TAS Homo sapiens 456216 R-HSA-69195 https://reactome.org/PathwayBrowser/#/R-HSA-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 TAS Homo sapiens 456216 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 456216 R-HSA-69604 https://reactome.org/PathwayBrowser/#/R-HSA-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 TAS Homo sapiens 456216 R-HSA-69608 https://reactome.org/PathwayBrowser/#/R-HSA-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 TAS Homo sapiens 456216 R-HSA-69685 https://reactome.org/PathwayBrowser/#/R-HSA-69685 CHEK2 phosphorylates TP53 TAS Homo sapiens 456216 R-HSA-69754 https://reactome.org/PathwayBrowser/#/R-HSA-69754 Phosphorylation of proteins involved in G2/M transition by active Cyclin A1:Cdc2 complexes TAS Homo sapiens 456216 R-HSA-69756 https://reactome.org/PathwayBrowser/#/R-HSA-69756 Phosphorylation of proteins involved in G2/M transition by active Cyclin A2:Cdc2 complexes TAS Homo sapiens 456216 R-HSA-69891 https://reactome.org/PathwayBrowser/#/R-HSA-69891 Phosphorylation and activation of CHEK2 by ATM TAS Homo sapiens 456216 R-HSA-70333 https://reactome.org/PathwayBrowser/#/R-HSA-70333 KHK dimer phosphorylates Fru to Fru 1-P TAS Homo sapiens 456216 R-HSA-70349 https://reactome.org/PathwayBrowser/#/R-HSA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate TAS Homo sapiens 456216 R-HSA-70355 https://reactome.org/PathwayBrowser/#/R-HSA-70355 GALK1 phosphorylates Gal to Gal1P TAS Homo sapiens 456216 R-HSA-70420 https://reactome.org/PathwayBrowser/#/R-HSA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P TAS Homo sapiens 456216 R-HSA-70467 https://reactome.org/PathwayBrowser/#/R-HSA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP TAS Homo sapiens 456216 R-HSA-70486 https://reactome.org/PathwayBrowser/#/R-HSA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG TAS Homo sapiens 456216 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 456216 R-HSA-70555 https://reactome.org/PathwayBrowser/#/R-HSA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] TAS Homo sapiens 456216 R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] TAS Homo sapiens 456216 R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] TAS Homo sapiens 456216 R-HSA-70606 https://reactome.org/PathwayBrowser/#/R-HSA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] TAS Homo sapiens 456216 R-HSA-70773 https://reactome.org/PathwayBrowser/#/R-HSA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] TAS Homo sapiens 456216 R-HSA-70967 https://reactome.org/PathwayBrowser/#/R-HSA-70967 IDH3 complex decarboxylates isocitrate TAS Homo sapiens 456216 R-HSA-70997 https://reactome.org/PathwayBrowser/#/R-HSA-70997 SUCLG1/A2 cleaves succinyl-CoA TAS Homo sapiens 456216 R-HSA-71031 https://reactome.org/PathwayBrowser/#/R-HSA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate TAS Homo sapiens 456216 R-HSA-71401 https://reactome.org/PathwayBrowser/#/R-HSA-71401 OGDH dimer decarboxylates 2-OG TAS Homo sapiens 456216 R-HSA-71541 https://reactome.org/PathwayBrowser/#/R-HSA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP TAS Homo sapiens 456216 R-HSA-71588 https://reactome.org/PathwayBrowser/#/R-HSA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP TAS Homo sapiens 456216 R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 456216 R-HSA-71802 https://reactome.org/PathwayBrowser/#/R-HSA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP TAS Homo sapiens 456216 R-HSA-71850 https://reactome.org/PathwayBrowser/#/R-HSA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP TAS Homo sapiens 456216 R-HSA-72621 https://reactome.org/PathwayBrowser/#/R-HSA-72621 Ribosomal scanning TAS Homo sapiens 456216 R-HSA-72647 https://reactome.org/PathwayBrowser/#/R-HSA-72647 Cap-bound mRNA is activated by helicases TAS Homo sapiens 456216 R-HSA-727819 https://reactome.org/PathwayBrowser/#/R-HSA-727819 TAK1 phosphorylates MKK6 TAS Homo sapiens 456216 R-HSA-73548 https://reactome.org/PathwayBrowser/#/R-HSA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) TAS Homo sapiens 456216 R-HSA-73577 https://reactome.org/PathwayBrowser/#/R-HSA-73577 CAD hexamer transforms L-Gln to CAP TAS Homo sapiens 456216 R-HSA-73598 https://reactome.org/PathwayBrowser/#/R-HSA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) TAS Homo sapiens 456216 R-HSA-73599 https://reactome.org/PathwayBrowser/#/R-HSA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] TAS Homo sapiens 456216 R-HSA-73632 https://reactome.org/PathwayBrowser/#/R-HSA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] TAS Homo sapiens 456216 R-HSA-73635 https://reactome.org/PathwayBrowser/#/R-HSA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] TAS Homo sapiens 456216 R-HSA-73647 https://reactome.org/PathwayBrowser/#/R-HSA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] TAS Homo sapiens 456216 R-HSA-73722 https://reactome.org/PathwayBrowser/#/R-HSA-73722 Phosphorylation of UBF-1:rDNA Promoter TAS Homo sapiens 456216 R-HSA-73788 https://reactome.org/PathwayBrowser/#/R-HSA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) TAS Homo sapiens 456216 R-HSA-73805 https://reactome.org/PathwayBrowser/#/R-HSA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi TAS Homo sapiens 456216 R-HSA-73810 https://reactome.org/PathwayBrowser/#/R-HSA-73810 FGAM + ATP => AIR + ADP + Pi TAS Homo sapiens 456216 R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 456216 R-HSA-73814 https://reactome.org/PathwayBrowser/#/R-HSA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi TAS Homo sapiens 456216 R-HSA-74207 https://reactome.org/PathwayBrowser/#/R-HSA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) TAS Homo sapiens 456216 R-HSA-74220 https://reactome.org/PathwayBrowser/#/R-HSA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) TAS Homo sapiens 456216 R-HSA-74615 https://reactome.org/PathwayBrowser/#/R-HSA-74615 PRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP IEA Homo sapiens 456216 R-HSA-74711 https://reactome.org/PathwayBrowser/#/R-HSA-74711 Phosphorylation of IRS TAS Homo sapiens 456216 R-HSA-74715 https://reactome.org/PathwayBrowser/#/R-HSA-74715 Autophosphorylation of insulin receptor TAS Homo sapiens 456216 R-HSA-74742 https://reactome.org/PathwayBrowser/#/R-HSA-74742 Phosphorylation of SHC1 TAS Homo sapiens 456216 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 456216 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 456216 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 456216 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 456216 R-HSA-75010 https://reactome.org/PathwayBrowser/#/R-HSA-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 TAS Homo sapiens 456216 R-HSA-75028 https://reactome.org/PathwayBrowser/#/R-HSA-75028 Phosphorylation of Wee1 kinase by Chk1 IEA Homo sapiens 456216 R-HSA-751040 https://reactome.org/PathwayBrowser/#/R-HSA-751040 PKC phosphorylates G alpha (z) IEA Homo sapiens 456216 R-HSA-75125 https://reactome.org/PathwayBrowser/#/R-HSA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) TAS Homo sapiens 456216 R-HSA-75126 https://reactome.org/PathwayBrowser/#/R-HSA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] TAS Homo sapiens 456216 R-HSA-75809 https://reactome.org/PathwayBrowser/#/R-HSA-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 TAS Homo sapiens 456216 R-HSA-75820 https://reactome.org/PathwayBrowser/#/R-HSA-75820 Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta IEA Homo sapiens 456216 R-HSA-75848 https://reactome.org/PathwayBrowser/#/R-HSA-75848 ACLY tetramer transforms CIT to Ac-CoA TAS Homo sapiens 456216 R-HSA-75851 https://reactome.org/PathwayBrowser/#/R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 456216 R-HSA-75887 https://reactome.org/PathwayBrowser/#/R-HSA-75887 Conversion of Glycerol to Glycerol-3-phosphate TAS Homo sapiens 456216 R-HSA-75949 https://reactome.org/PathwayBrowser/#/R-HSA-75949 RNA Polymerase II Promoter Opening: First Transition TAS Homo sapiens 456216 R-HSA-77071 https://reactome.org/PathwayBrowser/#/R-HSA-77071 Phosphorylation (Ser5) of RNA pol II CTD TAS Homo sapiens 456216 R-HSA-873918 https://reactome.org/PathwayBrowser/#/R-HSA-873918 Transphosphorylation of JAK1 TAS Homo sapiens 456216 R-HSA-873919 https://reactome.org/PathwayBrowser/#/R-HSA-873919 Phosphorylation of JAK2 TAS Homo sapiens 456216 R-HSA-873922 https://reactome.org/PathwayBrowser/#/R-HSA-873922 Phosphorylation of STAT1 by JAK kinases TAS Homo sapiens 456216 R-HSA-873924 https://reactome.org/PathwayBrowser/#/R-HSA-873924 Phosphorylation of IFNGR1 by JAK kinases TAS Homo sapiens 456216 R-HSA-879907 https://reactome.org/PathwayBrowser/#/R-HSA-879907 Tyrosine kinases phosphorylate the receptor TAS Homo sapiens 456216 R-HSA-879909 https://reactome.org/PathwayBrowser/#/R-HSA-879909 Activation of STAT5a/b by JAK2 TAS Homo sapiens 456216 R-HSA-879910 https://reactome.org/PathwayBrowser/#/R-HSA-879910 JAK2 is phosphorylated, activated TAS Homo sapiens 456216 R-HSA-8847638 https://reactome.org/PathwayBrowser/#/R-HSA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane TAS Homo sapiens 456216 R-HSA-8847977 https://reactome.org/PathwayBrowser/#/R-HSA-8847977 FRK phosphorylates PTEN TAS Homo sapiens 456216 R-HSA-8848005 https://reactome.org/PathwayBrowser/#/R-HSA-8848005 ERBB2 promotes PTK6 autophosphorylation TAS Homo sapiens 456216 R-HSA-8848053 https://reactome.org/PathwayBrowser/#/R-HSA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol TAS Homo sapiens 456216 R-HSA-8848077 https://reactome.org/PathwayBrowser/#/R-HSA-8848077 PTK6 phosphorylates STAP2 TAS Homo sapiens 456216 R-HSA-8848124 https://reactome.org/PathwayBrowser/#/R-HSA-8848124 PTK6 phosphorylates STAT3 TAS Homo sapiens 456216 R-HSA-8848436 https://reactome.org/PathwayBrowser/#/R-HSA-8848436 PTK6 phosphorylates CDKN1B TAS Homo sapiens 456216 R-HSA-8848606 https://reactome.org/PathwayBrowser/#/R-HSA-8848606 PTK6 phosphorylates PXN TAS Homo sapiens 456216 R-HSA-8848726 https://reactome.org/PathwayBrowser/#/R-HSA-8848726 PTK6 phosphorylates BCAR1 TAS Homo sapiens 456216 R-HSA-8848758 https://reactome.org/PathwayBrowser/#/R-HSA-8848758 PTK6 phosphorylates AKT1 TAS Homo sapiens 456216 R-HSA-8848776 https://reactome.org/PathwayBrowser/#/R-HSA-8848776 PTK6 phosphorylates DOK1 TAS Homo sapiens 456216 R-HSA-8848818 https://reactome.org/PathwayBrowser/#/R-HSA-8848818 PTK6 phosphorylates CBL TAS Homo sapiens 456216 R-HSA-8848873 https://reactome.org/PathwayBrowser/#/R-HSA-8848873 PTK6 phosphorylates ARAP1 TAS Homo sapiens 456216 R-HSA-8848975 https://reactome.org/PathwayBrowser/#/R-HSA-8848975 PTK6 phosphorylates KHDRBS1 TAS Homo sapiens 456216 R-HSA-8849032 https://reactome.org/PathwayBrowser/#/R-HSA-8849032 PTK6 phosphorylates KHDRBS2 TAS Homo sapiens 456216 R-HSA-8849042 https://reactome.org/PathwayBrowser/#/R-HSA-8849042 PTK6 phosphorylates KHDRBS3 TAS Homo sapiens 456216 R-HSA-8849068 https://reactome.org/PathwayBrowser/#/R-HSA-8849068 PTK6 phosphorylates ARHGAP35 TAS Homo sapiens 456216 R-HSA-8849102 https://reactome.org/PathwayBrowser/#/R-HSA-8849102 SRMS phosphorylates PTK6 TAS Homo sapiens 456216 R-HSA-8849353 https://reactome.org/PathwayBrowser/#/R-HSA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER TAS Homo sapiens 456216 R-HSA-8849463 https://reactome.org/PathwayBrowser/#/R-HSA-8849463 PTK6 phosphorylates SFPQ TAS Homo sapiens 456216 R-HSA-8850527 https://reactome.org/PathwayBrowser/#/R-HSA-8850527 PDCL releases folded G-beta from TRiC/CCT TAS Homo sapiens 456216 R-HSA-8850529 https://reactome.org/PathwayBrowser/#/R-HSA-8850529 RGS proteins bind GNB5 and CCT/TRiC TAS Homo sapiens 456216 R-HSA-8850534 https://reactome.org/PathwayBrowser/#/R-HSA-8850534 PDCL promotes G-protein beta 5 folding TAS Homo sapiens 456216 R-HSA-8850539 https://reactome.org/PathwayBrowser/#/R-HSA-8850539 Release of GNB5:RGS dimers from CCT/TRiC TAS Homo sapiens 456216 R-HSA-8850945 https://reactome.org/PathwayBrowser/#/R-HSA-8850945 Casein kinase II phosphorylates PTEN TAS Homo sapiens 456216 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 456216 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 456216 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 456216 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 456216 R-HSA-8851797 https://reactome.org/PathwayBrowser/#/R-HSA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated TAS Homo sapiens 456216 R-HSA-8851890 https://reactome.org/PathwayBrowser/#/R-HSA-8851890 MET phosphorylates SHC1-2 TAS Homo sapiens 456216 R-HSA-8851933 https://reactome.org/PathwayBrowser/#/R-HSA-8851933 MET phosphorylates GAB1 TAS Homo sapiens 456216 R-HSA-8852019 https://reactome.org/PathwayBrowser/#/R-HSA-8852019 MET bound PI3K generates PIP3 TAS Homo sapiens 456216 R-HSA-8852306 https://reactome.org/PathwayBrowser/#/R-HSA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends TAS Homo sapiens 456216 R-HSA-8852317 https://reactome.org/PathwayBrowser/#/R-HSA-8852317 PLK1 phosphorylates GTSE1 TAS Homo sapiens 456216 R-HSA-8852552 https://reactome.org/PathwayBrowser/#/R-HSA-8852552 MST1R autophosphorylates TAS Homo sapiens 456216 R-HSA-8853309 https://reactome.org/PathwayBrowser/#/R-HSA-8853309 Autocatalytic phosphorylation of FGFR3 fusions TAS Homo sapiens 456216 R-HSA-8853313 https://reactome.org/PathwayBrowser/#/R-HSA-8853313 FGFR2 fusions autophosphorylate TAS Homo sapiens 456216 R-HSA-8853325 https://reactome.org/PathwayBrowser/#/R-HSA-8853325 Plasma membrane FGFR1 fusions autophosphorylate TAS Homo sapiens 456216 R-HSA-8853419 https://reactome.org/PathwayBrowser/#/R-HSA-8853419 TPX2 promotes AURKA autophosphorylation TAS Homo sapiens 456216 R-HSA-8853444 https://reactome.org/PathwayBrowser/#/R-HSA-8853444 AURKA phosphorylates PHLDA1 TAS Homo sapiens 456216 R-HSA-8853774 https://reactome.org/PathwayBrowser/#/R-HSA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated TAS Homo sapiens 456216 R-HSA-8853792 https://reactome.org/PathwayBrowser/#/R-HSA-8853792 RET tyrosine phosphorylation TAS Homo sapiens 456216 R-HSA-8854908 https://reactome.org/PathwayBrowser/#/R-HSA-8854908 PKA phosphorylates RET:GDNF:GFRA dimer TAS Homo sapiens 456216 R-HSA-8855237 https://reactome.org/PathwayBrowser/#/R-HSA-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 TAS Homo sapiens 456216 R-HSA-8856813 https://reactome.org/PathwayBrowser/#/R-HSA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 TAS Homo sapiens 456216 R-HSA-8857555 https://reactome.org/PathwayBrowser/#/R-HSA-8857555 EGFR phosphorylates GPNMB TAS Homo sapiens 456216 R-HSA-8857577 https://reactome.org/PathwayBrowser/#/R-HSA-8857577 LINC01139 facilitates PTK6 autophosphorylation TAS Homo sapiens 456216 R-HSA-8857583 https://reactome.org/PathwayBrowser/#/R-HSA-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 TAS Homo sapiens 456216 R-HSA-8857925 https://reactome.org/PathwayBrowser/#/R-HSA-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 TAS Homo sapiens 456216 R-HSA-8863007 https://reactome.org/PathwayBrowser/#/R-HSA-8863007 p25-bound CDK5 phosphorylates CDC25B TAS Homo sapiens 456216 R-HSA-8863011 https://reactome.org/PathwayBrowser/#/R-HSA-8863011 p25-bound CDK5 phosphorylates CDC25C TAS Homo sapiens 456216 R-HSA-8863014 https://reactome.org/PathwayBrowser/#/R-HSA-8863014 p25-bound CDK5 phosphorylates CDC25A TAS Homo sapiens 456216 R-HSA-8863895 https://reactome.org/PathwayBrowser/#/R-HSA-8863895 IKKB phosphorylates SNAP23 TAS Homo sapiens 456216 R-HSA-8865774 https://reactome.org/PathwayBrowser/#/R-HSA-8865774 TTLLs polyglutamylate tubulin TAS Homo sapiens 456216 R-HSA-8866268 https://reactome.org/PathwayBrowser/#/R-HSA-8866268 ADBRK1,2 phosphorylate AVPR2 TAS Homo sapiens 456216 R-HSA-8866542 https://reactome.org/PathwayBrowser/#/R-HSA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol TAS Homo sapiens 456216 R-HSA-8866854 https://reactome.org/PathwayBrowser/#/R-HSA-8866854 VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol TAS Homo sapiens 456216 R-HSA-8867041 https://reactome.org/PathwayBrowser/#/R-HSA-8867041 EGFR phosphorylates EPS15 TAS Homo sapiens 456216 R-HSA-8867370 https://reactome.org/PathwayBrowser/#/R-HSA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin TAS Homo sapiens 456216 R-HSA-8868066 https://reactome.org/PathwayBrowser/#/R-HSA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 TAS Homo sapiens 456216 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 456216 R-HSA-8868118 https://reactome.org/PathwayBrowser/#/R-HSA-8868118 MAPK12 phosphorylates PTPN3 TAS Homo sapiens 456216 R-HSA-8868260 https://reactome.org/PathwayBrowser/#/R-HSA-8868260 CDK5:p25 phosphorylates GOLGA2 IEA Homo sapiens 456216 R-HSA-8868340 https://reactome.org/PathwayBrowser/#/R-HSA-8868340 CDK5:p25 phosphorylates lamin B1 IEA Homo sapiens 456216 R-HSA-8868344 https://reactome.org/PathwayBrowser/#/R-HSA-8868344 CDK5:p25 phosphorylates lamin A IEA Homo sapiens 456216 R-HSA-8868567 https://reactome.org/PathwayBrowser/#/R-HSA-8868567 CDK5:p25 phosphorylates PRDX1 IEA Homo sapiens 456216 R-HSA-8868573 https://reactome.org/PathwayBrowser/#/R-HSA-8868573 CDK5:p25 phosphorylates PRDX2 IEA Homo sapiens 456216 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 456216 R-HSA-8868666 https://reactome.org/PathwayBrowser/#/R-HSA-8868666 CDK5:p25 phosphorylates JUN IEA Homo sapiens 456216 R-HSA-8869606 https://reactome.org/PathwayBrowser/#/R-HSA-8869606 NMRK1 phosphorylates NAR to yield NAMN TAS Homo sapiens 456216 R-HSA-8869607 https://reactome.org/PathwayBrowser/#/R-HSA-8869607 NMRK2 phosphorylates NAR to yield NAMN TAS Homo sapiens 456216 R-HSA-8869627 https://reactome.org/PathwayBrowser/#/R-HSA-8869627 NMRK2 phosphorylates NR to yield NMN TAS Homo sapiens 456216 R-HSA-8869633 https://reactome.org/PathwayBrowser/#/R-HSA-8869633 NMRK1 phosphorylates NR to yield NMN TAS Homo sapiens 456216 R-HSA-8870558 https://reactome.org/PathwayBrowser/#/R-HSA-8870558 CDK5:p25 phosphorylates FOXO3 IEA Homo sapiens 456216 R-HSA-8871373 https://reactome.org/PathwayBrowser/#/R-HSA-8871373 BMX phosphorylates RUFY1 TAS Homo sapiens 456216 R-HSA-8873929 https://reactome.org/PathwayBrowser/#/R-HSA-8873929 Casein kinase II phosphorylates STARD10 TAS Homo sapiens 456216 R-HSA-8874078 https://reactome.org/PathwayBrowser/#/R-HSA-8874078 PTK2 autophosphorylates TAS Homo sapiens 456216 R-HSA-8874080 https://reactome.org/PathwayBrowser/#/R-HSA-8874080 SRC phosphorylates PTK2 TAS Homo sapiens 456216 R-HSA-8874082 https://reactome.org/PathwayBrowser/#/R-HSA-8874082 MET phosphorylates PTK2 TAS Homo sapiens 456216 R-HSA-8875451 https://reactome.org/PathwayBrowser/#/R-HSA-8875451 MET phosphorylates CBL TAS Homo sapiens 456216 R-HSA-8875817 https://reactome.org/PathwayBrowser/#/R-HSA-8875817 MET phosphorylates STAT3 TAS Homo sapiens 456216 R-HSA-8876230 https://reactome.org/PathwayBrowser/#/R-HSA-8876230 InlB:MET dimer trans-autophophorylates TAS Homo sapiens 456216 R-HSA-8876246 https://reactome.org/PathwayBrowser/#/R-HSA-8876246 InlB-activated MET phosphorylates CBL IEA Homo sapiens 456216 R-HSA-8876446 https://reactome.org/PathwayBrowser/#/R-HSA-8876446 p-ULK1 phosphorylates DENND3 TAS Homo sapiens 456216 R-HSA-8876889 https://reactome.org/PathwayBrowser/#/R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 456216 R-HSA-8876948 https://reactome.org/PathwayBrowser/#/R-HSA-8876948 SRC phosphorylates InlA-bound CDH1 and CTNNB1 TAS Homo sapiens 456216 R-HSA-8877691 https://reactome.org/PathwayBrowser/#/R-HSA-8877691 MAP2K6 phosphorylates PIP4K2B TAS Homo sapiens 456216 R-HSA-8878050 https://reactome.org/PathwayBrowser/#/R-HSA-8878050 HIPK2 phosphorylates RUNX1 and EP300 TAS Homo sapiens 456216 R-HSA-8878054 https://reactome.org/PathwayBrowser/#/R-HSA-8878054 HIPK2 phosphorylates RUNX1 TAS Homo sapiens 456216 R-HSA-8931653 https://reactome.org/PathwayBrowser/#/R-HSA-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 TAS Homo sapiens 456216 R-HSA-8932284 https://reactome.org/PathwayBrowser/#/R-HSA-8932284 PKC phosphorylates NFE2L2 IEA Homo sapiens 456216 R-HSA-8932322 https://reactome.org/PathwayBrowser/#/R-HSA-8932322 CK2 phosphorylates NFE2L2 IEA Homo sapiens 456216 R-HSA-8933446 https://reactome.org/PathwayBrowser/#/R-HSA-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling TAS Homo sapiens 456216 R-HSA-8934446 https://reactome.org/PathwayBrowser/#/R-HSA-8934446 Activated PKC phosphorylates SHC1 TAS Homo sapiens 456216 R-HSA-8937728 https://reactome.org/PathwayBrowser/#/R-HSA-8937728 SRC phosphorylates RUNX1 IEA Homo sapiens 456216 R-HSA-8937807 https://reactome.org/PathwayBrowser/#/R-HSA-8937807 SRC phosphorylates RUNX3 TAS Homo sapiens 456216 R-HSA-8937844 https://reactome.org/PathwayBrowser/#/R-HSA-8937844 SRC,YES1 phosphorylate YAP1 IEA Homo sapiens 456216 R-HSA-8939203 https://reactome.org/PathwayBrowser/#/R-HSA-8939203 HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex TAS Homo sapiens 456216 R-HSA-8939963 https://reactome.org/PathwayBrowser/#/R-HSA-8939963 Activated AKT phosphorylates RUNX2 IEA Homo sapiens 456216 R-HSA-8940100 https://reactome.org/PathwayBrowser/#/R-HSA-8940100 CDK1 phosphorylates VCPIP1 TAS Homo sapiens 456216 R-HSA-8942575 https://reactome.org/PathwayBrowser/#/R-HSA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG TAS Homo sapiens 456216 R-HSA-8942607 https://reactome.org/PathwayBrowser/#/R-HSA-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes TAS Homo sapiens 456216 R-HSA-8942836 https://reactome.org/PathwayBrowser/#/R-HSA-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 TAS Homo sapiens 456216 R-HSA-8944454 https://reactome.org/PathwayBrowser/#/R-HSA-8944454 mTORC1 phosphorylates MAF1 TAS Homo sapiens 456216 R-HSA-8948039 https://reactome.org/PathwayBrowser/#/R-HSA-8948039 FUNDC1 is phosphorylated by CK2 TAS Homo sapiens 456216 R-HSA-8948143 https://reactome.org/PathwayBrowser/#/R-HSA-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 TAS Homo sapiens 456216 R-HSA-8948146 https://reactome.org/PathwayBrowser/#/R-HSA-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 TAS Homo sapiens 456216 R-HSA-8948757 https://reactome.org/PathwayBrowser/#/R-HSA-8948757 AKT phosphorylates MKRN1 TAS Homo sapiens 456216 R-HSA-8950269 https://reactome.org/PathwayBrowser/#/R-HSA-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor TAS Homo sapiens 456216 R-HSA-8950340 https://reactome.org/PathwayBrowser/#/R-HSA-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation TAS Homo sapiens 456216 R-HSA-8950354 https://reactome.org/PathwayBrowser/#/R-HSA-8950354 STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interaction IEA Homo sapiens 456216 R-HSA-8950364 https://reactome.org/PathwayBrowser/#/R-HSA-8950364 IL23R in IL23:IL23 receptor complex is phosphorylated IEA Homo sapiens 456216 R-HSA-8950405 https://reactome.org/PathwayBrowser/#/R-HSA-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated TAS Homo sapiens 456216 R-HSA-8950423 https://reactome.org/PathwayBrowser/#/R-HSA-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated TAS Homo sapiens 456216 R-HSA-8950453 https://reactome.org/PathwayBrowser/#/R-HSA-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 TAS Homo sapiens 456216 R-HSA-8950485 https://reactome.org/PathwayBrowser/#/R-HSA-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction TAS Homo sapiens 456216 R-HSA-8950537 https://reactome.org/PathwayBrowser/#/R-HSA-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated TAS Homo sapiens 456216 R-HSA-8950591 https://reactome.org/PathwayBrowser/#/R-HSA-8950591 JAK2, TYK2 in IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 are phosphorylated IEA Homo sapiens 456216 R-HSA-8950757 https://reactome.org/PathwayBrowser/#/R-HSA-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated TAS Homo sapiens 456216 R-HSA-8952289 https://reactome.org/PathwayBrowser/#/R-HSA-8952289 FAM20C phosphorylates FAM20C substrates TAS Homo sapiens 456216 R-HSA-8954327 https://reactome.org/PathwayBrowser/#/R-HSA-8954327 UCKL1 phosphorylates urindine, cytidine TAS Homo sapiens 456216 R-HSA-8955030 https://reactome.org/PathwayBrowser/#/R-HSA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ TAS Homo sapiens 456216 R-HSA-8955706 https://reactome.org/PathwayBrowser/#/R-HSA-8955706 TTL ligates L-Tyr to the carboxy terminus of detyr-alpha tubulin:beta tubulin IEA Homo sapiens 456216 R-HSA-8955844 https://reactome.org/PathwayBrowser/#/R-HSA-8955844 RBKS phosphorylates ribose to R5P TAS Homo sapiens 456216 R-HSA-8955869 https://reactome.org/PathwayBrowser/#/R-HSA-8955869 Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin IEA Homo sapiens 456216 R-HSA-8956659 https://reactome.org/PathwayBrowser/#/R-HSA-8956659 ABL1 phosphorylates YAP1 TAS Homo sapiens 456216 R-HSA-8959719 https://reactome.org/PathwayBrowser/#/R-HSA-8959719 SHPK phosphorylates Sedo to Sedo7P TAS Homo sapiens 456216 R-HSA-8964242 https://reactome.org/PathwayBrowser/#/R-HSA-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC TAS Homo sapiens 456216 R-HSA-8964252 https://reactome.org/PathwayBrowser/#/R-HSA-8964252 G alpha (s):GTP:SRC catalyzes SRC to p-Y419-SRC TAS Homo sapiens 456216 R-HSA-8982163 https://reactome.org/PathwayBrowser/#/R-HSA-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 TAS Homo sapiens 456216 R-HSA-8983059 https://reactome.org/PathwayBrowser/#/R-HSA-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex TAS Homo sapiens 456216 R-HSA-8983063 https://reactome.org/PathwayBrowser/#/R-HSA-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated TAS Homo sapiens 456216 R-HSA-8983300 https://reactome.org/PathwayBrowser/#/R-HSA-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 TAS Homo sapiens 456216 R-HSA-8983309 https://reactome.org/PathwayBrowser/#/R-HSA-8983309 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates SHC1 IEA Homo sapiens 456216 R-HSA-8983371 https://reactome.org/PathwayBrowser/#/R-HSA-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 TAS Homo sapiens 456216 R-HSA-8983424 https://reactome.org/PathwayBrowser/#/R-HSA-8983424 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:GAB2 phosphorylates GAB2 IEA Homo sapiens 456216 R-HSA-8983834 https://reactome.org/PathwayBrowser/#/R-HSA-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated TAS Homo sapiens 456216 R-HSA-8983835 https://reactome.org/PathwayBrowser/#/R-HSA-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 TAS Homo sapiens 456216 R-HSA-8983870 https://reactome.org/PathwayBrowser/#/R-HSA-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated TAS Homo sapiens 456216 R-HSA-8983872 https://reactome.org/PathwayBrowser/#/R-HSA-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 TAS Homo sapiens 456216 R-HSA-8984012 https://reactome.org/PathwayBrowser/#/R-HSA-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated TAS Homo sapiens 456216 R-HSA-8984014 https://reactome.org/PathwayBrowser/#/R-HSA-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 TAS Homo sapiens 456216 R-HSA-8985914 https://reactome.org/PathwayBrowser/#/R-HSA-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 TAS Homo sapiens 456216 R-HSA-8985973 https://reactome.org/PathwayBrowser/#/R-HSA-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 TAS Homo sapiens 456216 R-HSA-8985988 https://reactome.org/PathwayBrowser/#/R-HSA-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 TAS Homo sapiens 456216 R-HSA-8986937 https://reactome.org/PathwayBrowser/#/R-HSA-8986937 MECP2 is phosphorylated at T308 IEA Homo sapiens 456216 R-HSA-8986985 https://reactome.org/PathwayBrowser/#/R-HSA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 TAS Homo sapiens 456216 R-HSA-8986994 https://reactome.org/PathwayBrowser/#/R-HSA-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 TAS Homo sapiens 456216 R-HSA-8986995 https://reactome.org/PathwayBrowser/#/R-HSA-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA TAS Homo sapiens 456216 R-HSA-8987012 https://reactome.org/PathwayBrowser/#/R-HSA-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 TAS Homo sapiens 456216 R-HSA-8987040 https://reactome.org/PathwayBrowser/#/R-HSA-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 TAS Homo sapiens 456216 R-HSA-8987042 https://reactome.org/PathwayBrowser/#/R-HSA-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 TAS Homo sapiens 456216 R-HSA-8987070 https://reactome.org/PathwayBrowser/#/R-HSA-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 TAS Homo sapiens 456216 R-HSA-8987084 https://reactome.org/PathwayBrowser/#/R-HSA-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 TAS Homo sapiens 456216 R-HSA-8987096 https://reactome.org/PathwayBrowser/#/R-HSA-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 TAS Homo sapiens 456216 R-HSA-8987129 https://reactome.org/PathwayBrowser/#/R-HSA-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated TAS Homo sapiens 456216 R-HSA-8987141 https://reactome.org/PathwayBrowser/#/R-HSA-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 TAS Homo sapiens 456216 R-HSA-8987150 https://reactome.org/PathwayBrowser/#/R-HSA-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 TAS Homo sapiens 456216 R-HSA-8987179 https://reactome.org/PathwayBrowser/#/R-HSA-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 TAS Homo sapiens 456216 R-HSA-8987202 https://reactome.org/PathwayBrowser/#/R-HSA-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 TAS Homo sapiens 456216 R-HSA-8987255 https://reactome.org/PathwayBrowser/#/R-HSA-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 TAS Homo sapiens 456216 R-HSA-9006323 https://reactome.org/PathwayBrowser/#/R-HSA-9006323 Phospho-JAK2 phosphorylates EPOR IEA Homo sapiens 456216 R-HSA-9006332 https://reactome.org/PathwayBrowser/#/R-HSA-9006332 JAK2 transphosphorylates and is activated in response to Erythropoietin IEA Homo sapiens 456216 R-HSA-9006850 https://reactome.org/PathwayBrowser/#/R-HSA-9006850 IL21 receptor JAK phosphorylation TAS Homo sapiens 456216 R-HSA-9006870 https://reactome.org/PathwayBrowser/#/R-HSA-9006870 IL21 receptor STAT phosphorylation TAS Homo sapiens 456216 R-HSA-9006992 https://reactome.org/PathwayBrowser/#/R-HSA-9006992 MECP2 is phosphorylated at S423 IEA Homo sapiens 456216 R-HSA-9007539 https://reactome.org/PathwayBrowser/#/R-HSA-9007539 CHEK1 phosphorylates E2F6 TAS Homo sapiens 456216 R-HSA-9008043 https://reactome.org/PathwayBrowser/#/R-HSA-9008043 MAPK8 phosphorylation TAS Homo sapiens 456216 R-HSA-9008412 https://reactome.org/PathwayBrowser/#/R-HSA-9008412 CDK4 phosphorylates RUNX2 TAS Homo sapiens 456216 R-HSA-9008480 https://reactome.org/PathwayBrowser/#/R-HSA-9008480 GSK3B phosphorylates RUNX2 IEA Homo sapiens 456216 R-HSA-9008684 https://reactome.org/PathwayBrowser/#/R-HSA-9008684 TBK1 phosphorylation TAS Homo sapiens 456216 R-HSA-9009072 https://reactome.org/PathwayBrowser/#/R-HSA-9009072 STAT3 phosphorylation TAS Homo sapiens 456216 R-HSA-9009208 https://reactome.org/PathwayBrowser/#/R-HSA-9009208 Activated ERKs phosphorylate RUNX2 IEA Homo sapiens 456216 R-HSA-9009282 https://reactome.org/PathwayBrowser/#/R-HSA-9009282 CDK1 phosphorylates RUNX2 TAS Homo sapiens 456216 R-HSA-9009700 https://reactome.org/PathwayBrowser/#/R-HSA-9009700 IL2RB and IL2RG are phosphorylated IEA Homo sapiens 456216 R-HSA-9010681 https://reactome.org/PathwayBrowser/#/R-HSA-9010681 PKC phosphorylates ROBO3.1 TAS Homo sapiens 456216 R-HSA-9011241 https://reactome.org/PathwayBrowser/#/R-HSA-9011241 SRC phosphorylates ROBO3.1 in response to NTN1 IEA Homo sapiens 456216 R-HSA-9012319 https://reactome.org/PathwayBrowser/#/R-HSA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD TAS Homo sapiens 456216 R-HSA-9012650 https://reactome.org/PathwayBrowser/#/R-HSA-9012650 JAK2 and LYN phosphorylate STAT5 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 IEA Homo sapiens 456216 R-HSA-9013978 https://reactome.org/PathwayBrowser/#/R-HSA-9013978 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex TAS Homo sapiens 456216 R-HSA-9018572 https://reactome.org/PathwayBrowser/#/R-HSA-9018572 EGFR phosphorylates NOTCH3 TAS Homo sapiens 456216 R-HSA-9021357 https://reactome.org/PathwayBrowser/#/R-HSA-9021357 PRKCI phosphorylates ELF3 TAS Homo sapiens 456216 R-HSA-9021609 https://reactome.org/PathwayBrowser/#/R-HSA-9021609 ESR-associated SRC autophosphorylates TAS Homo sapiens 456216 R-HSA-9021627 https://reactome.org/PathwayBrowser/#/R-HSA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-9022314 https://reactome.org/PathwayBrowser/#/R-HSA-9022314 HIPK2 phosphorylates MECP2 TAS Homo sapiens 456216 R-HSA-9023132 https://reactome.org/PathwayBrowser/#/R-HSA-9023132 AURKB phosphorylates MECP2 at S423 IEA Homo sapiens 456216 R-HSA-9024726 https://reactome.org/PathwayBrowser/#/R-HSA-9024726 LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1 IEA Homo sapiens 456216 R-HSA-9026464 https://reactome.org/PathwayBrowser/#/R-HSA-9026464 BDNF-bound NTRK2 dimers trans-autophosphorylate IEA Homo sapiens 456216 R-HSA-9026502 https://reactome.org/PathwayBrowser/#/R-HSA-9026502 NTF3-bound NTRK2 dimers trans-autophosphorylate IEA Homo sapiens 456216 R-HSA-9026510 https://reactome.org/PathwayBrowser/#/R-HSA-9026510 NTF4-bound NTRK2 dimers trans-autophosphorylate IEA Homo sapiens 456216 R-HSA-9026579 https://reactome.org/PathwayBrowser/#/R-HSA-9026579 NTRK2 phosphorylates PLCG1 IEA Homo sapiens 456216 R-HSA-9026890 https://reactome.org/PathwayBrowser/#/R-HSA-9026890 NTRK2 phosphorylates SHC1 IEA Homo sapiens 456216 R-HSA-9027272 https://reactome.org/PathwayBrowser/#/R-HSA-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 TAS Homo sapiens 456216 R-HSA-9027273 https://reactome.org/PathwayBrowser/#/R-HSA-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 TAS Homo sapiens 456216 R-HSA-9027425 https://reactome.org/PathwayBrowser/#/R-HSA-9027425 LYN phosphorylates PLCG1,2 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:PLCG1,2 IEA Homo sapiens 456216 R-HSA-9028519 https://reactome.org/PathwayBrowser/#/R-HSA-9028519 NTRK2-activated PI3K generates PIP3 IEA Homo sapiens 456216 R-HSA-9028728 https://reactome.org/PathwayBrowser/#/R-HSA-9028728 NTRK2 phosphorylates FRS2 IEA Homo sapiens 456216 R-HSA-9029151 https://reactome.org/PathwayBrowser/#/R-HSA-9029151 JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1 IEA Homo sapiens 456216 R-HSA-9029155 https://reactome.org/PathwayBrowser/#/R-HSA-9029155 JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1 IEA Homo sapiens 456216 R-HSA-9032426 https://reactome.org/PathwayBrowser/#/R-HSA-9032426 NTRK2 phosphorylates FRS3 IEA Homo sapiens 456216 R-HSA-9032532 https://reactome.org/PathwayBrowser/#/R-HSA-9032532 NTRK2-bound FYN autophosphorylates IEA Homo sapiens 456216 R-HSA-9032601 https://reactome.org/PathwayBrowser/#/R-HSA-9032601 FYN-mediated phosphorylation of GRIN2B IEA Homo sapiens 456216 R-HSA-9032751 https://reactome.org/PathwayBrowser/#/R-HSA-9032751 Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3 TAS Homo sapiens 456216 R-HSA-9032854 https://reactome.org/PathwayBrowser/#/R-HSA-9032854 NTRK2 phosphorylates CDK5 IEA Homo sapiens 456216 R-HSA-9032863 https://reactome.org/PathwayBrowser/#/R-HSA-9032863 CDK5 phosphorylates NTRK2 IEA Homo sapiens 456216 R-HSA-9033284 https://reactome.org/PathwayBrowser/#/R-HSA-9033284 NTRK2 promotes TIAM1 phosphorylation IEA Homo sapiens 456216 R-HSA-9033499 https://reactome.org/PathwayBrowser/#/R-HSA-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol TAS Homo sapiens 456216 R-HSA-9033505 https://reactome.org/PathwayBrowser/#/R-HSA-9033505 PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12 IEA Homo sapiens 456216 R-HSA-9034714 https://reactome.org/PathwayBrowser/#/R-HSA-9034714 NTRK3 dimers trans-autophosphorylate TAS Homo sapiens 456216 R-HSA-9034814 https://reactome.org/PathwayBrowser/#/R-HSA-9034814 NTRK3 phosphorylates PLCG1 IEA Homo sapiens 456216 R-HSA-9034875 https://reactome.org/PathwayBrowser/#/R-HSA-9034875 NTRK3 phosphorylates SHC1 IEA Homo sapiens 456216 R-HSA-9037040 https://reactome.org/PathwayBrowser/#/R-HSA-9037040 SRC,FYN phosphorylate NTRK2 IEA Homo sapiens 456216 R-HSA-9038161 https://reactome.org/PathwayBrowser/#/R-HSA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG TAS Homo sapiens 456216 R-HSA-909552 https://reactome.org/PathwayBrowser/#/R-HSA-909552 Phosphorylation of STAT1 at Ser727 TAS Homo sapiens 456216 R-HSA-909718 https://reactome.org/PathwayBrowser/#/R-HSA-909718 Formation of p-STAT1 homodimer TAS Homo sapiens 456216 R-HSA-909726 https://reactome.org/PathwayBrowser/#/R-HSA-909726 Phosphorylation of STAT1 TAS Homo sapiens 456216 R-HSA-909729 https://reactome.org/PathwayBrowser/#/R-HSA-909729 Activation of JAK kinases TAS Homo sapiens 456216 R-HSA-909730 https://reactome.org/PathwayBrowser/#/R-HSA-909730 Phosphorylation of INFAR1 by TYK2 TAS Homo sapiens 456216 R-HSA-909732 https://reactome.org/PathwayBrowser/#/R-HSA-909732 Phosphorylation of STAT2 TAS Homo sapiens 456216 R-HSA-912470 https://reactome.org/PathwayBrowser/#/R-HSA-912470 ATR phosphorylates Histone H2A.X at unsynapsed regions IEA Homo sapiens 456216 R-HSA-912527 https://reactome.org/PathwayBrowser/#/R-HSA-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 TAS Homo sapiens 456216 R-HSA-912629 https://reactome.org/PathwayBrowser/#/R-HSA-912629 CBL is tyrosine phosphorylated IEA Homo sapiens 456216 R-HSA-913996 https://reactome.org/PathwayBrowser/#/R-HSA-913996 PKA/PKG phosphorylate Rap1GAP2 TAS Homo sapiens 456216 R-HSA-917693 https://reactome.org/PathwayBrowser/#/R-HSA-917693 ESCRT Disassembly TAS Homo sapiens 456216 R-HSA-917841 https://reactome.org/PathwayBrowser/#/R-HSA-917841 Acidification of Tf:TfR1 containing endosome TAS Homo sapiens 456216 R-HSA-917979 https://reactome.org/PathwayBrowser/#/R-HSA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-918229 https://reactome.org/PathwayBrowser/#/R-HSA-918229 Phosphorylation and release of IRF3/IRF7 TAS Homo sapiens 456216 R-HSA-927889 https://reactome.org/PathwayBrowser/#/R-HSA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) TAS Homo sapiens 456216 R-HSA-933525 https://reactome.org/PathwayBrowser/#/R-HSA-933525 Phosphorylation and release of IRF7 TAS Homo sapiens 456216 R-HSA-933530 https://reactome.org/PathwayBrowser/#/R-HSA-933530 Activation of IKK by MEKK1 TAS Homo sapiens 456216 R-HSA-934559 https://reactome.org/PathwayBrowser/#/R-HSA-934559 SPRY2 is phosphorylated by phosphorylated MNK1 TAS Homo sapiens 456216 R-HSA-936802 https://reactome.org/PathwayBrowser/#/R-HSA-936802 ATP7A transports cytosolic Cu2+ to extracellular region TAS Homo sapiens 456216 R-HSA-936883 https://reactome.org/PathwayBrowser/#/R-HSA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen TAS Homo sapiens 456216 R-HSA-936895 https://reactome.org/PathwayBrowser/#/R-HSA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen TAS Homo sapiens 456216 R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 456216 R-HSA-936951 https://reactome.org/PathwayBrowser/#/R-HSA-936951 Activation of TAK1 complex bound to activated TLR4 complex TAS Homo sapiens 456216 R-HSA-936991 https://reactome.org/PathwayBrowser/#/R-HSA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 TAS Homo sapiens 456216 R-HSA-937022 https://reactome.org/PathwayBrowser/#/R-HSA-937022 IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP TAS Homo sapiens 456216 R-HSA-937034 https://reactome.org/PathwayBrowser/#/R-HSA-937034 IRAK1 phosphorylates Pellino TAS Homo sapiens 456216 R-HSA-937059 https://reactome.org/PathwayBrowser/#/R-HSA-937059 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex TAS Homo sapiens 456216 R-HSA-937311 https://reactome.org/PathwayBrowser/#/R-HSA-937311 ATP12A:ATP4B exchanges K+ for H+ TAS Homo sapiens 456216 R-HSA-939763 https://reactome.org/PathwayBrowser/#/R-HSA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane TAS Homo sapiens 456216 R-HSA-947591 https://reactome.org/PathwayBrowser/#/R-HSA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane TAS Homo sapiens 456216 R-HSA-9603420 https://reactome.org/PathwayBrowser/#/R-HSA-9603420 Activated NTRK3 promotes SRC autophosphorylation TAS Homo sapiens 456216 R-HSA-9603445 https://reactome.org/PathwayBrowser/#/R-HSA-9603445 Activated NTRK3 stimulates PI3K activity IEA Homo sapiens 456216 R-HSA-9604328 https://reactome.org/PathwayBrowser/#/R-HSA-9604328 AKT1 phosphorylates NOTCH4 TAS Homo sapiens 456216 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 456216 R-HSA-9606159 https://reactome.org/PathwayBrowser/#/R-HSA-9606159 BTK autophosphorylates IEA Homo sapiens 456216 R-HSA-9606162 https://reactome.org/PathwayBrowser/#/R-HSA-9606162 Phosphorylated BTK phosphorylates PLCG2 IEA Homo sapiens 456216 R-HSA-9606163 https://reactome.org/PathwayBrowser/#/R-HSA-9606163 p-SYK and LYN phosphorylate BTK IEA Homo sapiens 456216 R-HSA-9606622 https://reactome.org/PathwayBrowser/#/R-HSA-9606622 GAB2 in Active FLT3:GRB2:GAB2 is phosphorylated IEA Homo sapiens 456216 R-HSA-9606883 https://reactome.org/PathwayBrowser/#/R-HSA-9606883 CD19 is phosphorylated IEA Homo sapiens 456216 R-HSA-9606884 https://reactome.org/PathwayBrowser/#/R-HSA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated TAS Homo sapiens 456216 R-HSA-9609860 https://reactome.org/PathwayBrowser/#/R-HSA-9609860 Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP IEA Homo sapiens 456216 R-HSA-9609899 https://reactome.org/PathwayBrowser/#/R-HSA-9609899 Tail-anchored protein:ASNA1:ADP binds WRB:CAMLG at the endoplasmic reticulum membrane IEA Homo sapiens 456216 R-HSA-9609917 https://reactome.org/PathwayBrowser/#/R-HSA-9609917 Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane IEA Homo sapiens 456216 R-HSA-9610153 https://reactome.org/PathwayBrowser/#/R-HSA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF TAS Homo sapiens 456216 R-HSA-9610156 https://reactome.org/PathwayBrowser/#/R-HSA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF TAS Homo sapiens 456216 R-HSA-9610163 https://reactome.org/PathwayBrowser/#/R-HSA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF TAS Homo sapiens 456216 R-HSA-9610627 https://reactome.org/PathwayBrowser/#/R-HSA-9610627 KIF17 transports GluN1:GluN2B (GRIN1:GRIN2B) NMDA receptors to the plasma membrane IEA Homo sapiens 456216 R-HSA-9612085 https://reactome.org/PathwayBrowser/#/R-HSA-9612085 SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs IEA Homo sapiens 456216 R-HSA-9612501 https://reactome.org/PathwayBrowser/#/R-HSA-9612501 SGK phosphorylates CREB1 TAS Homo sapiens 456216 R-HSA-9612509 https://reactome.org/PathwayBrowser/#/R-HSA-9612509 SGK phosphorylates SRF TAS Homo sapiens 456216 R-HSA-9612980 https://reactome.org/PathwayBrowser/#/R-HSA-9612980 BRAF in Rap1-GTP complex:BRAF complex autophosphorylates IEA Homo sapiens 456216 R-HSA-9612996 https://reactome.org/PathwayBrowser/#/R-HSA-9612996 NTRK1,2 in ADCYAP1(2-742):ADCYAP1R1:NTRK1,2 autophosphorylates IEA Homo sapiens 456216 R-HSA-9613023 https://reactome.org/PathwayBrowser/#/R-HSA-9613023 NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates IEA Homo sapiens 456216 R-HSA-9613530 https://reactome.org/PathwayBrowser/#/R-HSA-9613530 PRKAA2 phosphorylates PLINs IEA Homo sapiens 456216 R-HSA-9617583 https://reactome.org/PathwayBrowser/#/R-HSA-9617583 CaMKII autophosphorylates IEA Homo sapiens 456216 R-HSA-9618750 https://reactome.org/PathwayBrowser/#/R-HSA-9618750 CaMKII phosphorylates AMPA receptor IEA Homo sapiens 456216 R-HSA-9619125 https://reactome.org/PathwayBrowser/#/R-HSA-9619125 CaMKK phosphorylates CAMK4 IEA Homo sapiens 456216 R-HSA-9619355 https://reactome.org/PathwayBrowser/#/R-HSA-9619355 CaMKK autophosphorylates in the cytosol TAS Homo sapiens 456216 R-HSA-9619367 https://reactome.org/PathwayBrowser/#/R-HSA-9619367 CaMKKs phosphorylate CAMK1 IEA Homo sapiens 456216 R-HSA-9619478 https://reactome.org/PathwayBrowser/#/R-HSA-9619478 CAMKK2 phosphorylates AMPK IEA Homo sapiens 456216 R-HSA-9619515 https://reactome.org/PathwayBrowser/#/R-HSA-9619515 AMPK phosphorylates MAPT IEA Homo sapiens 456216 R-HSA-9619783 https://reactome.org/PathwayBrowser/#/R-HSA-9619783 CAMK1 phosphorylates ARHGEF7-1 IEA Homo sapiens 456216 R-HSA-9619843 https://reactome.org/PathwayBrowser/#/R-HSA-9619843 ERKs phosphorylate RSKs IEA Homo sapiens 456216 R-HSA-9620004 https://reactome.org/PathwayBrowser/#/R-HSA-9620004 RSKs autophosphorylate IEA Homo sapiens 456216 R-HSA-9624014 https://reactome.org/PathwayBrowser/#/R-HSA-9624014 SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 TAS Homo sapiens 456216 R-HSA-9624526 https://reactome.org/PathwayBrowser/#/R-HSA-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR TAS Homo sapiens 456216 R-HSA-9624800 https://reactome.org/PathwayBrowser/#/R-HSA-9624800 CDK1 phosphorylates LBR TAS Homo sapiens 456216 R-HSA-9625487 https://reactome.org/PathwayBrowser/#/R-HSA-9625487 PTK2 autophosphorylates downstream of EGFR TAS Homo sapiens 456216 R-HSA-9626817 https://reactome.org/PathwayBrowser/#/R-HSA-9626817 PKC phosphorylates NCF1 TAS Homo sapiens 456216 R-HSA-9626832 https://reactome.org/PathwayBrowser/#/R-HSA-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 TAS Homo sapiens 456216 R-HSA-9626880 https://reactome.org/PathwayBrowser/#/R-HSA-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 TAS Homo sapiens 456216 R-HSA-9627089 https://reactome.org/PathwayBrowser/#/R-HSA-9627089 CASP9 is phosphorylated at T412 TAS Homo sapiens 456216 R-HSA-9632858 https://reactome.org/PathwayBrowser/#/R-HSA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation TAS Homo sapiens 456216 R-HSA-9632868 https://reactome.org/PathwayBrowser/#/R-HSA-9632868 CDKN1B is phosphorylated in response to estrogen TAS Homo sapiens 456216 R-HSA-9633008 https://reactome.org/PathwayBrowser/#/R-HSA-9633008 p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1 IEA Homo sapiens 456216 R-HSA-9633742 https://reactome.org/PathwayBrowser/#/R-HSA-9633742 EIF2AK4 (GCN2) dimer autophosphorylates IEA Homo sapiens 456216 R-HSA-9634390 https://reactome.org/PathwayBrowser/#/R-HSA-9634390 ERBB2 homodimer phosphorylates SHC1 TAS Homo sapiens 456216 R-HSA-9634702 https://reactome.org/PathwayBrowser/#/R-HSA-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 TAS Homo sapiens 456216 R-HSA-9645137 https://reactome.org/PathwayBrowser/#/R-HSA-9645137 Activator phosphorylates STAT5 IEA Homo sapiens 456216 R-HSA-9645442 https://reactome.org/PathwayBrowser/#/R-HSA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex TAS Homo sapiens 456216 R-HSA-9645535 https://reactome.org/PathwayBrowser/#/R-HSA-9645535 ALPK1 phosphorylates TIFA TAS Homo sapiens 456216 R-HSA-9648089 https://reactome.org/PathwayBrowser/#/R-HSA-9648089 NEK6 and NEK7 phosphorylate EML4 TAS Homo sapiens 456216 R-HSA-9648883 https://reactome.org/PathwayBrowser/#/R-HSA-9648883 p-T-EIF2AK1:ferriheme dimer autophosphorylates IEA Homo sapiens 456216 R-HSA-9648888 https://reactome.org/PathwayBrowser/#/R-HSA-9648888 p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) IEA Homo sapiens 456216 R-HSA-964958 https://reactome.org/PathwayBrowser/#/R-HSA-964958 2xPDXK:2xZn2+ phosphorylates PXA TAS Homo sapiens 456216 R-HSA-964962 https://reactome.org/PathwayBrowser/#/R-HSA-964962 2xPDKX:2xZn2+ phosphorylates PDX TAS Homo sapiens 456216 R-HSA-964970 https://reactome.org/PathwayBrowser/#/R-HSA-964970 2xPDXK:2xZn2+ phosphorylates PXL TAS Homo sapiens 456216 R-HSA-9650858 https://reactome.org/PathwayBrowser/#/R-HSA-9650858 Meglitinides bind ABCC8 TAS Homo sapiens 456216 R-HSA-9652165 https://reactome.org/PathwayBrowser/#/R-HSA-9652165 MAP2K mutants constitutively phosphorylate MAPKs TAS Homo sapiens 456216 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 456216 R-HSA-9653503 https://reactome.org/PathwayBrowser/#/R-HSA-9653503 KRAS4B is phosphorylated on serine 181 TAS Homo sapiens 456216 R-HSA-9656212 https://reactome.org/PathwayBrowser/#/R-HSA-9656212 Phosphorylation of RAF1 mutants TAS Homo sapiens 456216 R-HSA-9656214 https://reactome.org/PathwayBrowser/#/R-HSA-9656214 MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants TAS Homo sapiens 456216 R-HSA-9656215 https://reactome.org/PathwayBrowser/#/R-HSA-9656215 RAF1 mutant complexes phosphorylate MAP2K dimer TAS Homo sapiens 456216 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 456216 R-HSA-9661417 https://reactome.org/PathwayBrowser/#/R-HSA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-9662114 https://reactome.org/PathwayBrowser/#/R-HSA-9662114 ATP2B2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region IEA Homo sapiens 456216 R-HSA-9662823 https://reactome.org/PathwayBrowser/#/R-HSA-9662823 PLK2, MAPK14 phosphorylate ADAM17 TAS Homo sapiens 456216 R-HSA-9664214 https://reactome.org/PathwayBrowser/#/R-HSA-9664214 ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region IEA Homo sapiens 456216 R-HSA-9664261 https://reactome.org/PathwayBrowser/#/R-HSA-9664261 Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK TAS Homo sapiens 456216 R-HSA-9664275 https://reactome.org/PathwayBrowser/#/R-HSA-9664275 Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers TAS Homo sapiens 456216 R-HSA-9664278 https://reactome.org/PathwayBrowser/#/R-HSA-9664278 Phosphorylation and activation of PLCG due to FCGR3A effect TAS Homo sapiens 456216 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 456216 R-HSA-9664664 https://reactome.org/PathwayBrowser/#/R-HSA-9664664 PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 converts PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-9664940 https://reactome.org/PathwayBrowser/#/R-HSA-9664940 PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR converts PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-9664976 https://reactome.org/PathwayBrowser/#/R-HSA-9664976 Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1 TAS Homo sapiens 456216 R-HSA-9665032 https://reactome.org/PathwayBrowser/#/R-HSA-9665032 Phosphorylated heterodimers of ERBB2 KD mutants and EGFR phosphorylate PLCG1 TAS Homo sapiens 456216 R-HSA-9665389 https://reactome.org/PathwayBrowser/#/R-HSA-9665389 Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate TAS Homo sapiens 456216 R-HSA-9665406 https://reactome.org/PathwayBrowser/#/R-HSA-9665406 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate SHC1 TAS Homo sapiens 456216 R-HSA-9665407 https://reactome.org/PathwayBrowser/#/R-HSA-9665407 PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3 TAS Homo sapiens 456216 R-HSA-9665411 https://reactome.org/PathwayBrowser/#/R-HSA-9665411 Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate PLCG1 TAS Homo sapiens 456216 R-HSA-9665704 https://reactome.org/PathwayBrowser/#/R-HSA-9665704 Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1 TAS Homo sapiens 456216 R-HSA-9665705 https://reactome.org/PathwayBrowser/#/R-HSA-9665705 Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1 TAS Homo sapiens 456216 R-HSA-9665709 https://reactome.org/PathwayBrowser/#/R-HSA-9665709 ERBB2 TMD/JMD heterodimers trans-autophosphorylate TAS Homo sapiens 456216 R-HSA-9666425 https://reactome.org/PathwayBrowser/#/R-HSA-9666425 p-6Y-SYK phosphorylates VAV1,2,3 TAS Homo sapiens 456216 R-HSA-9666458 https://reactome.org/PathwayBrowser/#/R-HSA-9666458 IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole TAS Homo sapiens 456216 R-HSA-9668415 https://reactome.org/PathwayBrowser/#/R-HSA-9668415 VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope TAS Homo sapiens 456216 R-HSA-9668419 https://reactome.org/PathwayBrowser/#/R-HSA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites TAS Homo sapiens 456216 R-HSA-9669890 https://reactome.org/PathwayBrowser/#/R-HSA-9669890 Constitutive phosphorylation of kinase domain KIT mutants TAS Homo sapiens 456216 R-HSA-9669911 https://reactome.org/PathwayBrowser/#/R-HSA-9669911 Phosphorylation of juxtamembrane domain KIT mutants TAS Homo sapiens 456216 R-HSA-9670412 https://reactome.org/PathwayBrowser/#/R-HSA-9670412 Phosphorylation of STATs downstream of KIT mutants TAS Homo sapiens 456216 R-HSA-9670418 https://reactome.org/PathwayBrowser/#/R-HSA-9670418 Phosphorylation of JAK2 downstream of KIT mutants TAS Homo sapiens 456216 R-HSA-9670433 https://reactome.org/PathwayBrowser/#/R-HSA-9670433 KIT mutants:PI3K catalyze synthesis of PIP3 TAS Homo sapiens 456216 R-HSA-9672162 https://reactome.org/PathwayBrowser/#/R-HSA-9672162 PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of PDGFRA extracellular domain dimers TAS Homo sapiens 456216 R-HSA-9672173 https://reactome.org/PathwayBrowser/#/R-HSA-9672173 Autophosphorylation of PDGFRA extracellular domain dimers TAS Homo sapiens 456216 R-HSA-9672175 https://reactome.org/PathwayBrowser/#/R-HSA-9672175 Autophosphorylation of PDGFR mutant dimers TAS Homo sapiens 456216 R-HSA-9672177 https://reactome.org/PathwayBrowser/#/R-HSA-9672177 PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of mutant PDGFR TAS Homo sapiens 456216 R-HSA-9673284 https://reactome.org/PathwayBrowser/#/R-HSA-9673284 GTP-bound RAC1 contributes to MAPK8 activation TAS Homo sapiens 456216 R-HSA-9673346 https://reactome.org/PathwayBrowser/#/R-HSA-9673346 Unknown kinase phosphorylates p-DVL IEA Homo sapiens 456216 R-HSA-9673756 https://reactome.org/PathwayBrowser/#/R-HSA-9673756 Autophosphorylation of cytosolic PDGFRA and PDGFRB fusion proteins TAS Homo sapiens 456216 R-HSA-9673761 https://reactome.org/PathwayBrowser/#/R-HSA-9673761 Autophosphorylation of membrane-tethered fusions of PDGFRA or PDGFRB TAS Homo sapiens 456216 R-HSA-9673789 https://reactome.org/PathwayBrowser/#/R-HSA-9673789 Activated JNK phosphorylates c-JUN TAS Homo sapiens 456216 R-HSA-9674546 https://reactome.org/PathwayBrowser/#/R-HSA-9674546 CSF3 dimer:2xCSF3R:LYN:JAK1 induces phosphorylation of JAK1 IEA Homo sapiens 456216 R-HSA-9674558 https://reactome.org/PathwayBrowser/#/R-HSA-9674558 p-Y-JAK1 phosphorylates CSF3R in CSF3 dimer:2xCSF3R:LYN:p-Y-JAK1 IEA Homo sapiens 456216 R-HSA-9674567 https://reactome.org/PathwayBrowser/#/R-HSA-9674567 p-Y-JAK1,2 phosphorylates STAT1,3,5 in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-Y-JAK2:p-TYK2 IEA Homo sapiens 456216 R-HSA-9674808 https://reactome.org/PathwayBrowser/#/R-HSA-9674808 CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 binds and phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2) IEA Homo sapiens 456216 R-HSA-9676071 https://reactome.org/PathwayBrowser/#/R-HSA-9676071 CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK IEA Homo sapiens 456216 R-HSA-9680248 https://reactome.org/PathwayBrowser/#/R-HSA-9680248 Phosphorylation of extracellular domain KIT mutants TAS Homo sapiens 456216 R-HSA-9680348 https://reactome.org/PathwayBrowser/#/R-HSA-9680348 PIK3R1:PIK3CA,B,D (PI3K), PLCG2 (PLCgamma2), SHC1 (SHC), PTPN11 (SHP2), GRB2:GAB2, GRB2:GAB3, GRAP2 (MONA), CBL:GRB2, INPP5D (SHIP1), INPPL1 (SHIP2) bind PolyUb,p-8Y-CSF1R and are activated IEA Homo sapiens 456216 R-HSA-9680389 https://reactome.org/PathwayBrowser/#/R-HSA-9680389 CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2 IEA Homo sapiens 456216 R-HSA-9682695 https://reactome.org/PathwayBrowser/#/R-HSA-9682695 nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template TAS Homo sapiens 456216 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 456216 R-HSA-9684118 https://reactome.org/PathwayBrowser/#/R-HSA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER TAS Homo sapiens 456216 R-HSA-9686521 https://reactome.org/PathwayBrowser/#/R-HSA-9686521 CDK2:CCNA phosphorylates TERF2 TAS Homo sapiens 456216 R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 456216 R-HSA-9695834 https://reactome.org/PathwayBrowser/#/R-HSA-9695834 Constitutive phosphorylation of FLT3 mutants TAS Homo sapiens 456216 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 456216 R-HSA-9698003 https://reactome.org/PathwayBrowser/#/R-HSA-9698003 FLT3 mutants phosphorylate GAB2 TAS Homo sapiens 456216 R-HSA-9698005 https://reactome.org/PathwayBrowser/#/R-HSA-9698005 FLT3 ITD mutants phosphorylate STAT5 TAS Homo sapiens 456216 R-HSA-9699578 https://reactome.org/PathwayBrowser/#/R-HSA-9699578 Active FLT3 phosphorylates CDKN1B TAS Homo sapiens 456216 R-HSA-9699579 https://reactome.org/PathwayBrowser/#/R-HSA-9699579 AKT phosphorylates FOXO3 downstream of FLT3 TAS Homo sapiens 456216 R-HSA-9700164 https://reactome.org/PathwayBrowser/#/R-HSA-9700164 Active ALK phosphorylates FRS2 IEA Homo sapiens 456216 R-HSA-9700168 https://reactome.org/PathwayBrowser/#/R-HSA-9700168 Active ALK phosphorylates IRS1 TAS Homo sapiens 456216 R-HSA-9700171 https://reactome.org/PathwayBrowser/#/R-HSA-9700171 Active ALK phosphorylates PLCG1 TAS Homo sapiens 456216 R-HSA-9700175 https://reactome.org/PathwayBrowser/#/R-HSA-9700175 Active ALK phosphorylates SHC1 TAS Homo sapiens 456216 R-HSA-9700181 https://reactome.org/PathwayBrowser/#/R-HSA-9700181 Autophosphorylation of ALK fusions TAS Homo sapiens 456216 R-HSA-9700186 https://reactome.org/PathwayBrowser/#/R-HSA-9700186 Autophosphorylation of point mutants of ALK TAS Homo sapiens 456216 R-HSA-9700193 https://reactome.org/PathwayBrowser/#/R-HSA-9700193 ALK mutants phosphorylate SHC1 TAS Homo sapiens 456216 R-HSA-9700647 https://reactome.org/PathwayBrowser/#/R-HSA-9700647 Active ALK phosphorylates SRC IEA Homo sapiens 456216 R-HSA-9701488 https://reactome.org/PathwayBrowser/#/R-HSA-9701488 Active ALK phosphorylates JAK3 TAS Homo sapiens 456216 R-HSA-9703437 https://reactome.org/PathwayBrowser/#/R-HSA-9703437 FLT3 fusion dimers autophosphorylate TAS Homo sapiens 456216 R-HSA-9703438 https://reactome.org/PathwayBrowser/#/R-HSA-9703438 FLT3 fusions phosphorylate GAB2 TAS Homo sapiens 456216 R-HSA-9705320 https://reactome.org/PathwayBrowser/#/R-HSA-9705320 TBK1, IKBKE are autophosphorylated at Ser172 TAS Homo sapiens 456216 R-HSA-9706344 https://reactome.org/PathwayBrowser/#/R-HSA-9706344 FLT3 phosphorylates GRB10 TAS Homo sapiens 456216 R-HSA-9706350 https://reactome.org/PathwayBrowser/#/R-HSA-9706350 FLT3 phosphorylates CBL TAS Homo sapiens 456216 R-HSA-9706399 https://reactome.org/PathwayBrowser/#/R-HSA-9706399 RHOBTB3 hydrolyzes ATP TAS Homo sapiens 456216 R-HSA-9709918 https://reactome.org/PathwayBrowser/#/R-HSA-9709918 PTK6 phosphorylates STAT3 IEA Homo sapiens 456216 R-HSA-9712082 https://reactome.org/PathwayBrowser/#/R-HSA-9712082 ALK fusions phosphorylate IRS1 TAS Homo sapiens 456216 R-HSA-9712084 https://reactome.org/PathwayBrowser/#/R-HSA-9712084 PI3K synthesizes PIP3 downstream of ALK mutants TAS Homo sapiens 456216 R-HSA-9712085 https://reactome.org/PathwayBrowser/#/R-HSA-9712085 ALK mutants phosphorylate STAT3 TAS Homo sapiens 456216 R-HSA-9712086 https://reactome.org/PathwayBrowser/#/R-HSA-9712086 ALK fusions phosphorylate PLCG1 TAS Homo sapiens 456216 R-HSA-9712087 https://reactome.org/PathwayBrowser/#/R-HSA-9712087 ALK fusions phosphorylate FRS TAS Homo sapiens 456216 R-HSA-9725030 https://reactome.org/PathwayBrowser/#/R-HSA-9725030 MAPK1 phsophorylates ZC3HCF1 in a NPM-ALK-dependent manner TAS Homo sapiens 456216 R-HSA-9726848 https://reactome.org/PathwayBrowser/#/R-HSA-9726848 SRC phosphorylates RHOU IEA Homo sapiens 456216 R-HSA-9727198 https://reactome.org/PathwayBrowser/#/R-HSA-9727198 ATP4A:ATP4B exchanges K+ for H+ TAS Homo sapiens 456216 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 456216 R-HSA-9729300 https://reactome.org/PathwayBrowser/#/R-HSA-9729300 Unknown kinase phosphorylates nucleoprotein TAS Homo sapiens 456216 R-HSA-9729318 https://reactome.org/PathwayBrowser/#/R-HSA-9729318 CSNK1A1 phosphorylates nucleoprotein TAS Homo sapiens 456216 R-HSA-9729330 https://reactome.org/PathwayBrowser/#/R-HSA-9729330 SRPK1/2 phosphorylates nucleoprotein TAS Homo sapiens 456216 R-HSA-9731111 https://reactome.org/PathwayBrowser/#/R-HSA-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 TAS Homo sapiens 456216 R-HSA-9732738 https://reactome.org/PathwayBrowser/#/R-HSA-9732738 JAK1-mediated phosphorylation of RAF1 TAS Homo sapiens 456216 R-HSA-9732753 https://reactome.org/PathwayBrowser/#/R-HSA-9732753 JAK1-activated RAF1 phosphorylates MAPKs TAS Homo sapiens 456216 R-HSA-9733314 https://reactome.org/PathwayBrowser/#/R-HSA-9733314 CSF1R trans-autophosphorylates on tyrosine-561 IEA Homo sapiens 456216 R-HSA-9733323 https://reactome.org/PathwayBrowser/#/R-HSA-9733323 Src family kinases phosphorylate CBL in CSF1 dimer:p-Y561-CSF1R dimer:CBL IEA Homo sapiens 456216 R-HSA-9734547 https://reactome.org/PathwayBrowser/#/R-HSA-9734547 JAK2-activated MAPKs phosphorylate YBX1 TAS Homo sapiens 456216 R-HSA-9734687 https://reactome.org/PathwayBrowser/#/R-HSA-9734687 ORC6 is phosphorylated on T195 TAS Homo sapiens 456216 R-HSA-9748949 https://reactome.org/PathwayBrowser/#/R-HSA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP TAS Homo sapiens 456216 R-HSA-9748963 https://reactome.org/PathwayBrowser/#/R-HSA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP TAS Homo sapiens 456216 R-HSA-9748969 https://reactome.org/PathwayBrowser/#/R-HSA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP TAS Homo sapiens 456216 R-HSA-9748999 https://reactome.org/PathwayBrowser/#/R-HSA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP TAS Homo sapiens 456216 R-HSA-9749350 https://reactome.org/PathwayBrowser/#/R-HSA-9749350 ATP-dependent release of CDT1 from the OCCM complex IEA Homo sapiens 456216 R-HSA-9750546 https://reactome.org/PathwayBrowser/#/R-HSA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-9750617 https://reactome.org/PathwayBrowser/#/R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-9750656 https://reactome.org/PathwayBrowser/#/R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells TAS Homo sapiens 456216 R-HSA-975103 https://reactome.org/PathwayBrowser/#/R-HSA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation TAS Homo sapiens 456216 R-HSA-975106 https://reactome.org/PathwayBrowser/#/R-HSA-975106 Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 456216 R-HSA-975125 https://reactome.org/PathwayBrowser/#/R-HSA-975125 Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 456216 R-HSA-975134 https://reactome.org/PathwayBrowser/#/R-HSA-975134 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 TAS Homo sapiens 456216 R-HSA-975139 https://reactome.org/PathwayBrowser/#/R-HSA-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation TAS Homo sapiens 456216 R-HSA-975160 https://reactome.org/PathwayBrowser/#/R-HSA-975160 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 TAS Homo sapiens 456216 R-HSA-975170 https://reactome.org/PathwayBrowser/#/R-HSA-975170 IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 456216 R-HSA-975180 https://reactome.org/PathwayBrowser/#/R-HSA-975180 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 456216 R-HSA-9753278 https://reactome.org/PathwayBrowser/#/R-HSA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 456216 R-HSA-9753283 https://reactome.org/PathwayBrowser/#/R-HSA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 456216 R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 456216 R-HSA-9754974 https://reactome.org/PathwayBrowser/#/R-HSA-9754974 ADK phosphorylates RBV TAS Homo sapiens 456216 R-HSA-9754978 https://reactome.org/PathwayBrowser/#/R-HSA-9754978 Unknown kinase phosphorylates RBV-MP TAS Homo sapiens 456216 R-HSA-9755013 https://reactome.org/PathwayBrowser/#/R-HSA-9755013 NME1,2 hexamers phosphorylate RBV-DP TAS Homo sapiens 456216 R-HSA-9758486 https://reactome.org/PathwayBrowser/#/R-HSA-9758486 Unknown kinase phosphorylates 9b TAS Homo sapiens 456216 R-HSA-975853 https://reactome.org/PathwayBrowser/#/R-HSA-975853 Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR TAS Homo sapiens 456216 R-HSA-975861 https://reactome.org/PathwayBrowser/#/R-HSA-975861 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex TAS Homo sapiens 456216 R-HSA-975865 https://reactome.org/PathwayBrowser/#/R-HSA-975865 IRAK4 autophosphorylation within the complex activated TLR:MyD88 TAS Homo sapiens 456216 R-HSA-975874 https://reactome.org/PathwayBrowser/#/R-HSA-975874 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex TAS Homo sapiens 456216 R-HSA-975878 https://reactome.org/PathwayBrowser/#/R-HSA-975878 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR TAS Homo sapiens 456216 R-HSA-9759206 https://reactome.org/PathwayBrowser/#/R-HSA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol TAS Homo sapiens 456216 R-HSA-9759454 https://reactome.org/PathwayBrowser/#/R-HSA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells TAS Homo sapiens 456216 R-HSA-9759461 https://reactome.org/PathwayBrowser/#/R-HSA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells TAS Homo sapiens 456216 R-HSA-9760094 https://reactome.org/PathwayBrowser/#/R-HSA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer TAS Homo sapiens 456216 R-HSA-9762094 https://reactome.org/PathwayBrowser/#/R-HSA-9762094 GSK3B phosphorylates p-NFE2L2 TAS Homo sapiens 456216 R-HSA-9762209 https://reactome.org/PathwayBrowser/#/R-HSA-9762209 BACH1 is phosphorylated at tyrosine 483 TAS Homo sapiens 456216 R-HSA-9766532 https://reactome.org/PathwayBrowser/#/R-HSA-9766532 SQSTM1 oligomer is phosphorylated TAS Homo sapiens 456216 R-HSA-9769115 https://reactome.org/PathwayBrowser/#/R-HSA-9769115 MAPK1,(MAPK3) phosphorylates NPAS4 IEA Homo sapiens 456216 R-HSA-9770129 https://reactome.org/PathwayBrowser/#/R-HSA-9770129 Formation of the Spliceosomal A complex TAS Homo sapiens 456216 R-HSA-9770131 https://reactome.org/PathwayBrowser/#/R-HSA-9770131 Formation of the Spliceosomal B* complex TAS Homo sapiens 456216 R-HSA-9770141 https://reactome.org/PathwayBrowser/#/R-HSA-9770141 Formation of the Spliceosomal C* complex TAS Homo sapiens 456216 R-HSA-9770142 https://reactome.org/PathwayBrowser/#/R-HSA-9770142 Formation of the Spliceosomal B complex TAS Homo sapiens 456216 R-HSA-9770145 https://reactome.org/PathwayBrowser/#/R-HSA-9770145 Formation of the Spliceosomal Bact complex TAS Homo sapiens 456216 R-HSA-9770847 https://reactome.org/PathwayBrowser/#/R-HSA-9770847 Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) TAS Homo sapiens 456216 R-HSA-9772351 https://reactome.org/PathwayBrowser/#/R-HSA-9772351 Disassembly of the Intron Lariat Spliceosome (new) TAS Homo sapiens 456216 R-HSA-9773803 https://reactome.org/PathwayBrowser/#/R-HSA-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor TAS Homo sapiens 456216 R-HSA-9794120 https://reactome.org/PathwayBrowser/#/R-HSA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space TAS Homo sapiens 456216 R-HSA-9794572 https://reactome.org/PathwayBrowser/#/R-HSA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space TAS Homo sapiens 456216 R-HSA-9796053 https://reactome.org/PathwayBrowser/#/R-HSA-9796053 PRKCI phosphorylates NFE2L2 TAS Homo sapiens 456216 R-HSA-9796067 https://reactome.org/PathwayBrowser/#/R-HSA-9796067 PRKAA2 phosphorylates nuclear NFE2L2 TAS Homo sapiens 456216 R-HSA-9796081 https://reactome.org/PathwayBrowser/#/R-HSA-9796081 EIF2AK3 phosphorylates NFE2L2 IEA Homo sapiens 456216 R-HSA-9815501 https://reactome.org/PathwayBrowser/#/R-HSA-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 TAS Homo sapiens 456216 R-HSA-9817397 https://reactome.org/PathwayBrowser/#/R-HSA-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 TAS Homo sapiens 456216 R-HSA-9818789 https://reactome.org/PathwayBrowser/#/R-HSA-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 TAS Homo sapiens 456216 R-HSA-9819106 https://reactome.org/PathwayBrowser/#/R-HSA-9819106 ULK1 phosphorylates RIPK1 at S357 TAS Homo sapiens 456216 R-HSA-9821967 https://reactome.org/PathwayBrowser/#/R-HSA-9821967 SRPK1 phosphorylates PRM2 in PRM2:dsDNA IEA Homo sapiens 456216 R-HSA-9821982 https://reactome.org/PathwayBrowser/#/R-HSA-9821982 SRPK1 phosphorylates PRM1 in PRM1:dsDNA IEA Homo sapiens 456216 R-HSA-9823906 https://reactome.org/PathwayBrowser/#/R-HSA-9823906 TBK1 is phosphorylated within the activated TLR4 complex TAS Homo sapiens 456216 R-HSA-9824882 https://reactome.org/PathwayBrowser/#/R-HSA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex TAS Homo sapiens 456216 R-HSA-9824977 https://reactome.org/PathwayBrowser/#/R-HSA-9824977 MAPK1-dependent phosphorylation of MITF-M TAS Homo sapiens 456216 R-HSA-9824994 https://reactome.org/PathwayBrowser/#/R-HSA-9824994 RPS6KA1-dependent phosphorylation of MITF-M TAS Homo sapiens 456216 R-HSA-9824995 https://reactome.org/PathwayBrowser/#/R-HSA-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 TAS Homo sapiens 456216 R-HSA-9824999 https://reactome.org/PathwayBrowser/#/R-HSA-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 TAS Homo sapiens 456216 R-HSA-9825759 https://reactome.org/PathwayBrowser/#/R-HSA-9825759 MAPK-dependent phosphorylation of KARS TAS Homo sapiens 456216 R-HSA-982807 https://reactome.org/PathwayBrowser/#/R-HSA-982807 JAK2 phosphorylation of GHR TAS Homo sapiens 456216 R-HSA-982810 https://reactome.org/PathwayBrowser/#/R-HSA-982810 JAK2 phosphorylation TAS Homo sapiens 456216 R-HSA-9828205 https://reactome.org/PathwayBrowser/#/R-HSA-9828205 TBK1 is phosphorylated within the activated TLR3 complex TAS Homo sapiens 456216 R-HSA-9830706 https://reactome.org/PathwayBrowser/#/R-HSA-9830706 IKKε (IKBKE) is phosphorylated within the activated TLR3 complex TAS Homo sapiens 456216 R-HSA-983144 https://reactome.org/PathwayBrowser/#/R-HSA-983144 Transport of Antigen peptide in to ER TAS Homo sapiens 456216 R-HSA-9831514 https://reactome.org/PathwayBrowser/#/R-HSA-9831514 CK2 phosphorylates nascent P TAS Homo sapiens 456216 R-HSA-9831712 https://reactome.org/PathwayBrowser/#/R-HSA-9831712 M dimer is phosphorylated TAS Homo sapiens 456216 R-HSA-983259 https://reactome.org/PathwayBrowser/#/R-HSA-983259 Kinesins move along microtubules consuming ATP TAS Homo sapiens 456216 R-HSA-9833820 https://reactome.org/PathwayBrowser/#/R-HSA-9833820 PKR dimer autophosphorylates TAS Homo sapiens 456216 R-HSA-9835885 https://reactome.org/PathwayBrowser/#/R-HSA-9835885 p-PKR dimer phosphorylates eIF2-alpha TAS Homo sapiens 456216 R-HSA-9836159 https://reactome.org/PathwayBrowser/#/R-HSA-9836159 p-PKR dimer phosphorylates DHX9 TAS Homo sapiens 456216 R-HSA-9836184 https://reactome.org/PathwayBrowser/#/R-HSA-9836184 p-PKR dimer phosphorylates CDK1 TAS Homo sapiens 456216 R-HSA-9836322 https://reactome.org/PathwayBrowser/#/R-HSA-9836322 p-PKR dimer phosphorylates MKK6 TAS Homo sapiens 456216 R-HSA-9836362 https://reactome.org/PathwayBrowser/#/R-HSA-9836362 p-PKR dimer phosphorylates TP53 tetramer TAS Homo sapiens 456216 R-HSA-9836383 https://reactome.org/PathwayBrowser/#/R-HSA-9836383 p-PKR dimer phosphorylates ILF3:ILF2 TAS Homo sapiens 456216 R-HSA-9836404 https://reactome.org/PathwayBrowser/#/R-HSA-9836404 p-PKR dimer phosphorylates MAPT TAS Homo sapiens 456216 R-HSA-9836435 https://reactome.org/PathwayBrowser/#/R-HSA-9836435 p-PKR dimer phosphorylates SNCA TAS Homo sapiens 456216 R-HSA-9836449 https://reactome.org/PathwayBrowser/#/R-HSA-9836449 p-PKR dimer phosphorylates HIV tat TAS Homo sapiens 456216 R-HSA-9836515 https://reactome.org/PathwayBrowser/#/R-HSA-9836515 p-PKR dimer phosphorylates PTPN2 TAS Homo sapiens 456216 R-HSA-9836617 https://reactome.org/PathwayBrowser/#/R-HSA-9836617 p-PKR dimer phosphorylates SPHK1 TAS Homo sapiens 456216 R-HSA-9836664 https://reactome.org/PathwayBrowser/#/R-HSA-9836664 p-PKR dimer phosphorylates PPP2R5A TAS Homo sapiens 456216 R-HSA-9836927 https://reactome.org/PathwayBrowser/#/R-HSA-9836927 SUPV3L1 unwinds double-stranded mitochondiral RNA TAS Homo sapiens 456216 R-HSA-983703 https://reactome.org/PathwayBrowser/#/R-HSA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) TAS Homo sapiens 456216 R-HSA-983707 https://reactome.org/PathwayBrowser/#/R-HSA-983707 SYK autophosphorylates at the activated BCR TAS Homo sapiens 456216 R-HSA-983709 https://reactome.org/PathwayBrowser/#/R-HSA-983709 LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) IEA Homo sapiens 456216 R-HSA-9837333 https://reactome.org/PathwayBrowser/#/R-HSA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP TAS Homo sapiens 456216 R-HSA-9837337 https://reactome.org/PathwayBrowser/#/R-HSA-9837337 DCAKD phosphorylates DP-CoA TAS Homo sapiens 456216 R-HSA-9838004 https://reactome.org/PathwayBrowser/#/R-HSA-9838004 LONP1 degrades mitochondrial inner membrane proteins TAS Homo sapiens 456216 R-HSA-9838081 https://reactome.org/PathwayBrowser/#/R-HSA-9838081 LONP1 degrades mitochondrial matrix proteins TAS Homo sapiens 456216 R-HSA-9838289 https://reactome.org/PathwayBrowser/#/R-HSA-9838289 CLPXP degrades mitochondrial matrix proteins TAS Homo sapiens 456216 R-HSA-9838321 https://reactome.org/PathwayBrowser/#/R-HSA-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix TAS Homo sapiens 456216 R-HSA-9839059 https://reactome.org/PathwayBrowser/#/R-HSA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) TAS Homo sapiens 456216 R-HSA-9839105 https://reactome.org/PathwayBrowser/#/R-HSA-9839105 AFG3L2 degrades mitochondrial matrix proteins TAS Homo sapiens 456216 R-HSA-9839113 https://reactome.org/PathwayBrowser/#/R-HSA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins TAS Homo sapiens 456216 R-HSA-9839146 https://reactome.org/PathwayBrowser/#/R-HSA-9839146 YME1L1 degrades mitochondrial inner membrane proteins IEA Homo sapiens 456216 R-HSA-9839751 https://reactome.org/PathwayBrowser/#/R-HSA-9839751 YME1L1 degrades mitochondrial intermembrane space proteins IEA Homo sapiens 456216 R-HSA-9842648 https://reactome.org/PathwayBrowser/#/R-HSA-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 TAS Homo sapiens 456216 R-HSA-9842651 https://reactome.org/PathwayBrowser/#/R-HSA-9842651 Active LTK receptor phosphorylates SHC1 TAS Homo sapiens 456216 R-HSA-9842666 https://reactome.org/PathwayBrowser/#/R-HSA-9842666 Active LTK phosphorylates IRS1 TAS Homo sapiens 456216 R-HSA-9842667 https://reactome.org/PathwayBrowser/#/R-HSA-9842667 CLIP1-LTK fusion autophosphorylates TAS Homo sapiens 456216 R-HSA-9843721 https://reactome.org/PathwayBrowser/#/R-HSA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region TAS Homo sapiens 456216 R-HSA-9845033 https://reactome.org/PathwayBrowser/#/R-HSA-9845033 CLIP1-LTK promotes MAPK1 and MAPK3 phosphorylation TAS Homo sapiens 456216 R-HSA-9851078 https://reactome.org/PathwayBrowser/#/R-HSA-9851078 NPM1-ALK-dependent MAPK8,9 phosphorylation TAS Homo sapiens 456216 R-HSA-9851096 https://reactome.org/PathwayBrowser/#/R-HSA-9851096 NPM1-ALK- and JNK-dependent JUN phosphorylation TAS Homo sapiens 456216 R-HSA-9851102 https://reactome.org/PathwayBrowser/#/R-HSA-9851102 NPM1-ALK- and PI3K-dependent MDM2 phosphorylation TAS Homo sapiens 456216 R-HSA-9851114 https://reactome.org/PathwayBrowser/#/R-HSA-9851114 NPM1-ALK-dependent TYK2 phosphorylation TAS Homo sapiens 456216 R-HSA-9851142 https://reactome.org/PathwayBrowser/#/R-HSA-9851142 TYK2-dependent STAT1 and STAT3 phosphorylation TAS Homo sapiens 456216 R-HSA-9851972 https://reactome.org/PathwayBrowser/#/R-HSA-9851972 PLK1 phosphorylates FIRRM at S43 TAS Homo sapiens 456216 R-HSA-9853369 https://reactome.org/PathwayBrowser/#/R-HSA-9853369 PLK1 phosphorylates FIRMM at S744 TAS Homo sapiens 456216 R-HSA-9861642 https://reactome.org/PathwayBrowser/#/R-HSA-9861642 NEK1 phosphorylates ME1 TAS Homo sapiens 456216 R-HSA-994137 https://reactome.org/PathwayBrowser/#/R-HSA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 TAS Homo sapiens 456216 R-HSA-994140 https://reactome.org/PathwayBrowser/#/R-HSA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 TAS Homo sapiens 456216 R-HSA-997381 https://reactome.org/PathwayBrowser/#/R-HSA-997381 TDPK phosphorylates ThDP to ThTP TAS Homo sapiens 456216 R-MGA-5672766 https://reactome.org/PathwayBrowser/#/R-MGA-5672766 Turkey MYLK phosphorylates MRLCs of the non-muscle myosin II complex TAS Meleagris gallopavo 456216 R-MMU-1008248 https://reactome.org/PathwayBrowser/#/R-MMU-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Mus musculus 456216 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 456216 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 456216 R-MMU-109415 https://reactome.org/PathwayBrowser/#/R-MMU-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Mus musculus 456216 R-MMU-109624 https://reactome.org/PathwayBrowser/#/R-MMU-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Mus musculus 456216 R-MMU-109671 https://reactome.org/PathwayBrowser/#/R-MMU-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Mus musculus 456216 R-MMU-109699 https://reactome.org/PathwayBrowser/#/R-MMU-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-109702 https://reactome.org/PathwayBrowser/#/R-MMU-109702 PDPK1 phosphorylates AKT2 IEA Mus musculus 456216 R-MMU-109759 https://reactome.org/PathwayBrowser/#/R-MMU-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Mus musculus 456216 R-MMU-109822 https://reactome.org/PathwayBrowser/#/R-MMU-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Mus musculus 456216 R-MMU-109823 https://reactome.org/PathwayBrowser/#/R-MMU-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Mus musculus 456216 R-MMU-109860 https://reactome.org/PathwayBrowser/#/R-MMU-109860 MAP2K1 phosphorylates MAPK3 IEA Mus musculus 456216 R-MMU-109862 https://reactome.org/PathwayBrowser/#/R-MMU-109862 MAP2K2 phosphorylates MAPK1 IEA Mus musculus 456216 R-MMU-109903 https://reactome.org/PathwayBrowser/#/R-MMU-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Mus musculus 456216 R-MMU-110133 https://reactome.org/PathwayBrowser/#/R-MMU-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Mus musculus 456216 R-MMU-110137 https://reactome.org/PathwayBrowser/#/R-MMU-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Mus musculus 456216 R-MMU-110138 https://reactome.org/PathwayBrowser/#/R-MMU-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 456216 R-MMU-110141 https://reactome.org/PathwayBrowser/#/R-MMU-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Mus musculus 456216 R-MMU-110144 https://reactome.org/PathwayBrowser/#/R-MMU-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Mus musculus 456216 R-MMU-110145 https://reactome.org/PathwayBrowser/#/R-MMU-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Mus musculus 456216 R-MMU-1112510 https://reactome.org/PathwayBrowser/#/R-MMU-1112510 IL6ST is tyrosine phosphorylated IEA Mus musculus 456216 R-MMU-1112514 https://reactome.org/PathwayBrowser/#/R-MMU-1112514 JAK activation IEA Mus musculus 456216 R-MMU-1112602 https://reactome.org/PathwayBrowser/#/R-MMU-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Mus musculus 456216 R-MMU-1112703 https://reactome.org/PathwayBrowser/#/R-MMU-1112703 PTPN11 is phosphorylated IEA Mus musculus 456216 R-MMU-1112727 https://reactome.org/PathwayBrowser/#/R-MMU-1112727 Serine phosphorylation of STATs IEA Mus musculus 456216 R-MMU-111898 https://reactome.org/PathwayBrowser/#/R-MMU-111898 Phosphorylation of cPLA2 by ERK-2 IEA Mus musculus 456216 R-MMU-111915 https://reactome.org/PathwayBrowser/#/R-MMU-111915 CAMK4 autophosphorylates IEA Mus musculus 456216 R-MMU-111970 https://reactome.org/PathwayBrowser/#/R-MMU-111970 PKC phosphorylates GRK2 IEA Mus musculus 456216 R-MMU-112342 https://reactome.org/PathwayBrowser/#/R-MMU-112342 Inactivation of MAP2K1 by CDK1 IEA Mus musculus 456216 R-MMU-112381 https://reactome.org/PathwayBrowser/#/R-MMU-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Mus musculus 456216 R-MMU-114252 https://reactome.org/PathwayBrowser/#/R-MMU-114252 Cleavage of Procaspase-3 by the apoptosome IEA Mus musculus 456216 R-MMU-114254 https://reactome.org/PathwayBrowser/#/R-MMU-114254 CYCS binds to APAF1 IEA Mus musculus 456216 R-MMU-114259 https://reactome.org/PathwayBrowser/#/R-MMU-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Mus musculus 456216 R-MMU-114261 https://reactome.org/PathwayBrowser/#/R-MMU-114261 Cleavage of Procaspase-7 by the apoptosome IEA Mus musculus 456216 R-MMU-114600 https://reactome.org/PathwayBrowser/#/R-MMU-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Mus musculus 456216 R-MMU-114683 https://reactome.org/PathwayBrowser/#/R-MMU-114683 Phosphorylation of Platelet Sec-1 IEA Mus musculus 456216 R-MMU-114684 https://reactome.org/PathwayBrowser/#/R-MMU-114684 Phosphorylation of Syntaxin-4 IEA Mus musculus 456216 R-MMU-1168459 https://reactome.org/PathwayBrowser/#/R-MMU-1168459 Lyn activates ERK IEA Mus musculus 456216 R-MMU-1168635 https://reactome.org/PathwayBrowser/#/R-MMU-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Mus musculus 456216 R-MMU-1168638 https://reactome.org/PathwayBrowser/#/R-MMU-1168638 Activated IKK phosphorylates I-kappaB IEA Mus musculus 456216 R-MMU-1168923 https://reactome.org/PathwayBrowser/#/R-MMU-1168923 Stat5 tyrosine phosphorylation TAS Mus musculus 456216 R-MMU-1169206 https://reactome.org/PathwayBrowser/#/R-MMU-1169206 Jak2 phosphorylates Stat1/Stat3 TAS Mus musculus 456216 R-MMU-1169494 https://reactome.org/PathwayBrowser/#/R-MMU-1169494 Rasgrp1 and Rasgrp3 are recruited to the membrane and phosphorylated TAS Mus musculus 456216 R-MMU-1181149 https://reactome.org/PathwayBrowser/#/R-MMU-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Mus musculus 456216 R-MMU-1226094 https://reactome.org/PathwayBrowser/#/R-MMU-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Mus musculus 456216 R-MMU-1226095 https://reactome.org/PathwayBrowser/#/R-MMU-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Mus musculus 456216 R-MMU-1247935 https://reactome.org/PathwayBrowser/#/R-MMU-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Mus musculus 456216 R-MMU-1247960 https://reactome.org/PathwayBrowser/#/R-MMU-1247960 Activation of p38 MAPK IEA Mus musculus 456216 R-MMU-1250195 https://reactome.org/PathwayBrowser/#/R-MMU-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Mus musculus 456216 R-MMU-1250315 https://reactome.org/PathwayBrowser/#/R-MMU-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Mus musculus 456216 R-MMU-1250348 https://reactome.org/PathwayBrowser/#/R-MMU-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Mus musculus 456216 R-MMU-1250370 https://reactome.org/PathwayBrowser/#/R-MMU-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Mus musculus 456216 R-MMU-1250462 https://reactome.org/PathwayBrowser/#/R-MMU-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Mus musculus 456216 R-MMU-1295540 https://reactome.org/PathwayBrowser/#/R-MMU-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Mus musculus 456216 R-MMU-1295609 https://reactome.org/PathwayBrowser/#/R-MMU-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Mus musculus 456216 R-MMU-1295764 https://reactome.org/PathwayBrowser/#/R-MMU-1295764 IL7r is phosphorylated on Y449 TAS Mus musculus 456216 R-MMU-1306957 https://reactome.org/PathwayBrowser/#/R-MMU-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Mus musculus 456216 R-MMU-1306979 https://reactome.org/PathwayBrowser/#/R-MMU-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Mus musculus 456216 R-MMU-1307963 https://reactome.org/PathwayBrowser/#/R-MMU-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Mus musculus 456216 R-MMU-1358791 https://reactome.org/PathwayBrowser/#/R-MMU-1358791 Phosphorylation of USP8 by P-AKT IEA Mus musculus 456216 R-MMU-1362270 https://reactome.org/PathwayBrowser/#/R-MMU-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Mus musculus 456216 R-MMU-1369028 https://reactome.org/PathwayBrowser/#/R-MMU-1369028 ABCAs mediate lipid efflux IEA Mus musculus 456216 R-MMU-1369052 https://reactome.org/PathwayBrowser/#/R-MMU-1369052 ABCAs mediate lipid influx IEA Mus musculus 456216 R-MMU-1369065 https://reactome.org/PathwayBrowser/#/R-MMU-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Mus musculus 456216 R-MMU-1370505 https://reactome.org/PathwayBrowser/#/R-MMU-1370505 PRLR is phosphorylated at Ser-349 IEA Mus musculus 456216 R-MMU-139908 https://reactome.org/PathwayBrowser/#/R-MMU-139908 Phosphorylation of DLC2 by MAPK8 IEA Mus musculus 456216 R-MMU-139918 https://reactome.org/PathwayBrowser/#/R-MMU-139918 Phosphorylation of BIM by JNK IEA Mus musculus 456216 R-MMU-1433418 https://reactome.org/PathwayBrowser/#/R-MMU-1433418 Phosphorylation of JAK2 IEA Mus musculus 456216 R-MMU-1433454 https://reactome.org/PathwayBrowser/#/R-MMU-1433454 Phosphorylation of GAB2 by SFKs IEA Mus musculus 456216 R-MMU-1433488 https://reactome.org/PathwayBrowser/#/R-MMU-1433488 Phosphorylation of SHP2 by SFKs IEA Mus musculus 456216 R-MMU-1433506 https://reactome.org/PathwayBrowser/#/R-MMU-1433506 Phosphorylation of APS IEA Mus musculus 456216 R-MMU-1433508 https://reactome.org/PathwayBrowser/#/R-MMU-1433508 PKC alpha interacts with and phosphorylates KIT IEA Mus musculus 456216 R-MMU-1433514 https://reactome.org/PathwayBrowser/#/R-MMU-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Mus musculus 456216 R-MMU-1433542 https://reactome.org/PathwayBrowser/#/R-MMU-1433542 Phosphorylation and activation of VAV1 IEA Mus musculus 456216 R-MMU-1449573 https://reactome.org/PathwayBrowser/#/R-MMU-1449573 Fusion of Glut4 Vesicle with the Plasma Membrane TAS Mus musculus 456216 R-MMU-1449591 https://reactome.org/PathwayBrowser/#/R-MMU-1449591 Akt2 Phosphorylates Myosin 5a TAS Mus musculus 456216 R-MMU-1454711 https://reactome.org/PathwayBrowser/#/R-MMU-1454711 Ampk-alpha2 Phosphorylates Tbc1d1 TAS Mus musculus 456216 R-MMU-1454916 https://reactome.org/PathwayBrowser/#/R-MMU-1454916 The ABCC family mediates organic anion transport IEA Mus musculus 456216 R-MMU-1454928 https://reactome.org/PathwayBrowser/#/R-MMU-1454928 ABCG4 may mediate cholesterol efflux IEA Mus musculus 456216 R-MMU-1458507 https://reactome.org/PathwayBrowser/#/R-MMU-1458507 Akt2 Phosphorylates Rgc2 TAS Mus musculus 456216 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-1467466 https://reactome.org/PathwayBrowser/#/R-MMU-1467466 ABCA4 mediates atRAL transport IEA Mus musculus 456216 R-MMU-1470009 https://reactome.org/PathwayBrowser/#/R-MMU-1470009 Phosphorylation of STATs IEA Mus musculus 456216 R-MMU-1472121 https://reactome.org/PathwayBrowser/#/R-MMU-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Mus musculus 456216 R-MMU-1475422 https://reactome.org/PathwayBrowser/#/R-MMU-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Mus musculus 456216 R-MMU-1483004 https://reactome.org/PathwayBrowser/#/R-MMU-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Mus musculus 456216 R-MMU-1483222 https://reactome.org/PathwayBrowser/#/R-MMU-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Mus musculus 456216 R-MMU-1497853 https://reactome.org/PathwayBrowser/#/R-MMU-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Mus musculus 456216 R-MMU-1524186 https://reactome.org/PathwayBrowser/#/R-MMU-1524186 Phosphorylation of PLCgamma by PDGFR IEA Mus musculus 456216 R-MMU-1549526 https://reactome.org/PathwayBrowser/#/R-MMU-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Mus musculus 456216 R-MMU-156673 https://reactome.org/PathwayBrowser/#/R-MMU-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Mus musculus 456216 R-MMU-156678 https://reactome.org/PathwayBrowser/#/R-MMU-156678 Activation of Cdc25C IEA Mus musculus 456216 R-MMU-156682 https://reactome.org/PathwayBrowser/#/R-MMU-156682 PLK1 phosphorylates NUDC IEA Mus musculus 456216 R-MMU-156699 https://reactome.org/PathwayBrowser/#/R-MMU-156699 Inactivation of Wee1 kinase IEA Mus musculus 456216 R-MMU-156723 https://reactome.org/PathwayBrowser/#/R-MMU-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Mus musculus 456216 R-MMU-159101 https://reactome.org/PathwayBrowser/#/R-MMU-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Mus musculus 456216 R-MMU-1605464 https://reactome.org/PathwayBrowser/#/R-MMU-1605464 p38 Mapk phosphorylates Ppargc1a TAS Mus musculus 456216 R-MMU-1605475 https://reactome.org/PathwayBrowser/#/R-MMU-1605475 Ampk phosphorylates Ppargc1a TAS Mus musculus 456216 R-MMU-162352 https://reactome.org/PathwayBrowser/#/R-MMU-162352 Phosphorylation of PDE3B by AKT-1 TAS Mus musculus 456216 R-MMU-162657 https://reactome.org/PathwayBrowser/#/R-MMU-162657 Inactivation of Myt1 kinase IEA Mus musculus 456216 R-MMU-163010 https://reactome.org/PathwayBrowser/#/R-MMU-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Mus musculus 456216 R-MMU-163120 https://reactome.org/PathwayBrowser/#/R-MMU-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Mus musculus 456216 R-MMU-163215 https://reactome.org/PathwayBrowser/#/R-MMU-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Mus musculus 456216 R-MMU-1632857 https://reactome.org/PathwayBrowser/#/R-MMU-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Mus musculus 456216 R-MMU-163422 https://reactome.org/PathwayBrowser/#/R-MMU-163422 perilipin + 3 ATP -> phosphorylated perilipin + 3 ADP TAS Mus musculus 456216 R-MMU-1638803 https://reactome.org/PathwayBrowser/#/R-MMU-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Mus musculus 456216 R-MMU-1638845 https://reactome.org/PathwayBrowser/#/R-MMU-1638845 CERK phosphorylates CERA to form C1P IEA Mus musculus 456216 R-MMU-164832 https://reactome.org/PathwayBrowser/#/R-MMU-164832 ATPase synthesizes ATP IEA Mus musculus 456216 R-MMU-164840 https://reactome.org/PathwayBrowser/#/R-MMU-164840 ADP and Pi bind to ATPase IEA Mus musculus 456216 R-MMU-165162 https://reactome.org/PathwayBrowser/#/R-MMU-165162 Phosphorylation of TSC2 by PKB IEA Mus musculus 456216 R-MMU-165182 https://reactome.org/PathwayBrowser/#/R-MMU-165182 Phosphorylation of complexed TSC2 by PKB IEA Mus musculus 456216 R-MMU-165692 https://reactome.org/PathwayBrowser/#/R-MMU-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Mus musculus 456216 R-MMU-165718 https://reactome.org/PathwayBrowser/#/R-MMU-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Mus musculus 456216 R-MMU-165726 https://reactome.org/PathwayBrowser/#/R-MMU-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Mus musculus 456216 R-MMU-165758 https://reactome.org/PathwayBrowser/#/R-MMU-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Mus musculus 456216 R-MMU-165766 https://reactome.org/PathwayBrowser/#/R-MMU-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Mus musculus 456216 R-MMU-165777 https://reactome.org/PathwayBrowser/#/R-MMU-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Mus musculus 456216 R-MMU-166245 https://reactome.org/PathwayBrowser/#/R-MMU-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Mus musculus 456216 R-MMU-1675773 https://reactome.org/PathwayBrowser/#/R-MMU-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Mus musculus 456216 R-MMU-1675776 https://reactome.org/PathwayBrowser/#/R-MMU-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Mus musculus 456216 R-MMU-1675780 https://reactome.org/PathwayBrowser/#/R-MMU-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Mus musculus 456216 R-MMU-1675810 https://reactome.org/PathwayBrowser/#/R-MMU-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Mus musculus 456216 R-MMU-1675813 https://reactome.org/PathwayBrowser/#/R-MMU-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Mus musculus 456216 R-MMU-1675883 https://reactome.org/PathwayBrowser/#/R-MMU-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Mus musculus 456216 R-MMU-1675928 https://reactome.org/PathwayBrowser/#/R-MMU-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Mus musculus 456216 R-MMU-1675939 https://reactome.org/PathwayBrowser/#/R-MMU-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Mus musculus 456216 R-MMU-1675961 https://reactome.org/PathwayBrowser/#/R-MMU-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Mus musculus 456216 R-MMU-1675974 https://reactome.org/PathwayBrowser/#/R-MMU-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Mus musculus 456216 R-MMU-1676024 https://reactome.org/PathwayBrowser/#/R-MMU-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Mus musculus 456216 R-MMU-1676048 https://reactome.org/PathwayBrowser/#/R-MMU-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Mus musculus 456216 R-MMU-1676082 https://reactome.org/PathwayBrowser/#/R-MMU-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Mus musculus 456216 R-MMU-1676109 https://reactome.org/PathwayBrowser/#/R-MMU-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Mus musculus 456216 R-MMU-1676134 https://reactome.org/PathwayBrowser/#/R-MMU-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Mus musculus 456216 R-MMU-1676145 https://reactome.org/PathwayBrowser/#/R-MMU-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Mus musculus 456216 R-MMU-1676185 https://reactome.org/PathwayBrowser/#/R-MMU-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Mus musculus 456216 R-MMU-1676206 https://reactome.org/PathwayBrowser/#/R-MMU-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Mus musculus 456216 R-MMU-1678944 https://reactome.org/PathwayBrowser/#/R-MMU-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Mus musculus 456216 R-MMU-168053 https://reactome.org/PathwayBrowser/#/R-MMU-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Mus musculus 456216 R-MMU-168136 https://reactome.org/PathwayBrowser/#/R-MMU-168136 Activated JNKs phosphorylate c-JUN IEA Mus musculus 456216 R-MMU-168140 https://reactome.org/PathwayBrowser/#/R-MMU-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Mus musculus 456216 R-MMU-168162 https://reactome.org/PathwayBrowser/#/R-MMU-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Mus musculus 456216 R-MMU-169905 https://reactome.org/PathwayBrowser/#/R-MMU-169905 ARMS is phosphorylated by active TrkA receptor IEA Mus musculus 456216 R-MMU-170026 https://reactome.org/PathwayBrowser/#/R-MMU-170026 Protons are translocated from the intermembrane space to the matrix IEA Mus musculus 456216 R-MMU-170055 https://reactome.org/PathwayBrowser/#/R-MMU-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Mus musculus 456216 R-MMU-170070 https://reactome.org/PathwayBrowser/#/R-MMU-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Mus musculus 456216 R-MMU-170076 https://reactome.org/PathwayBrowser/#/R-MMU-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Mus musculus 456216 R-MMU-170087 https://reactome.org/PathwayBrowser/#/R-MMU-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Mus musculus 456216 R-MMU-170126 https://reactome.org/PathwayBrowser/#/R-MMU-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Mus musculus 456216 R-MMU-170843 https://reactome.org/PathwayBrowser/#/R-MMU-170843 TGFBR2 phosphorylates TGFBR1 IEA Mus musculus 456216 R-MMU-170868 https://reactome.org/PathwayBrowser/#/R-MMU-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Mus musculus 456216 R-MMU-170977 https://reactome.org/PathwayBrowser/#/R-MMU-170977 FRS2 is phosphorylated by active TrkA receptor IEA Mus musculus 456216 R-MMU-174079 https://reactome.org/PathwayBrowser/#/R-MMU-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Mus musculus 456216 R-MMU-174122 https://reactome.org/PathwayBrowser/#/R-MMU-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Mus musculus 456216 R-MMU-174164 https://reactome.org/PathwayBrowser/#/R-MMU-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Mus musculus 456216 R-MMU-174174 https://reactome.org/PathwayBrowser/#/R-MMU-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Mus musculus 456216 R-MMU-174251 https://reactome.org/PathwayBrowser/#/R-MMU-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Mus musculus 456216 R-MMU-174367 https://reactome.org/PathwayBrowser/#/R-MMU-174367 GCL ligates L-Glu to L-Cys IEA Mus musculus 456216 R-MMU-174389 https://reactome.org/PathwayBrowser/#/R-MMU-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Mus musculus 456216 R-MMU-174394 https://reactome.org/PathwayBrowser/#/R-MMU-174394 GSS:Mg2+ dimer synthesizes GSH IEA Mus musculus 456216 R-MMU-174438 https://reactome.org/PathwayBrowser/#/R-MMU-174438 Formation of the Flap Intermediate on the C-strand IEA Mus musculus 456216 R-MMU-174439 https://reactome.org/PathwayBrowser/#/R-MMU-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Mus musculus 456216 R-MMU-176116 https://reactome.org/PathwayBrowser/#/R-MMU-176116 Recruitment and activation of Chk1 IEA Mus musculus 456216 R-MMU-176298 https://reactome.org/PathwayBrowser/#/R-MMU-176298 Activation of claspin IEA Mus musculus 456216 R-MMU-177275 https://reactome.org/PathwayBrowser/#/R-MMU-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Mus musculus 456216 R-MMU-177284 https://reactome.org/PathwayBrowser/#/R-MMU-177284 PKA phosphorylates PDE4B IEA Mus musculus 456216 R-MMU-177930 https://reactome.org/PathwayBrowser/#/R-MMU-177930 GAB1 phosphorylation by EGFR kinase IEA Mus musculus 456216 R-MMU-177933 https://reactome.org/PathwayBrowser/#/R-MMU-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Mus musculus 456216 R-MMU-177934 https://reactome.org/PathwayBrowser/#/R-MMU-177934 EGFR autophosphorylation IEA Mus musculus 456216 R-MMU-177937 https://reactome.org/PathwayBrowser/#/R-MMU-177937 Phosphorylation of EGFR by SRC kinase IEA Mus musculus 456216 R-MMU-177939 https://reactome.org/PathwayBrowser/#/R-MMU-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Mus musculus 456216 R-MMU-1810473 https://reactome.org/PathwayBrowser/#/R-MMU-1810473 Recruitment Tbk1 to dsDNA:Dai followed by its activation TAS Mus musculus 456216 R-MMU-182969 https://reactome.org/PathwayBrowser/#/R-MMU-182969 Phosphorylation of CBL (EGFR:CBL) IEA Mus musculus 456216 R-MMU-183058 https://reactome.org/PathwayBrowser/#/R-MMU-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Mus musculus 456216 R-MMU-1855153 https://reactome.org/PathwayBrowser/#/R-MMU-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Mus musculus 456216 R-MMU-1855157 https://reactome.org/PathwayBrowser/#/R-MMU-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Mus musculus 456216 R-MMU-1855158 https://reactome.org/PathwayBrowser/#/R-MMU-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Mus musculus 456216 R-MMU-1855162 https://reactome.org/PathwayBrowser/#/R-MMU-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Mus musculus 456216 R-MMU-1855169 https://reactome.org/PathwayBrowser/#/R-MMU-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Mus musculus 456216 R-MMU-1855172 https://reactome.org/PathwayBrowser/#/R-MMU-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Mus musculus 456216 R-MMU-1855176 https://reactome.org/PathwayBrowser/#/R-MMU-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Mus musculus 456216 R-MMU-1855179 https://reactome.org/PathwayBrowser/#/R-MMU-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Mus musculus 456216 R-MMU-1855181 https://reactome.org/PathwayBrowser/#/R-MMU-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Mus musculus 456216 R-MMU-1855182 https://reactome.org/PathwayBrowser/#/R-MMU-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Mus musculus 456216 R-MMU-1855185 https://reactome.org/PathwayBrowser/#/R-MMU-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 456216 R-MMU-1855193 https://reactome.org/PathwayBrowser/#/R-MMU-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Mus musculus 456216 R-MMU-1855194 https://reactome.org/PathwayBrowser/#/R-MMU-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Mus musculus 456216 R-MMU-1855197 https://reactome.org/PathwayBrowser/#/R-MMU-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Mus musculus 456216 R-MMU-1855206 https://reactome.org/PathwayBrowser/#/R-MMU-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 456216 R-MMU-1855207 https://reactome.org/PathwayBrowser/#/R-MMU-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Mus musculus 456216 R-MMU-1855216 https://reactome.org/PathwayBrowser/#/R-MMU-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Mus musculus 456216 R-MMU-1855223 https://reactome.org/PathwayBrowser/#/R-MMU-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Mus musculus 456216 R-MMU-1855224 https://reactome.org/PathwayBrowser/#/R-MMU-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Mus musculus 456216 R-MMU-1855227 https://reactome.org/PathwayBrowser/#/R-MMU-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Mus musculus 456216 R-MMU-1855228 https://reactome.org/PathwayBrowser/#/R-MMU-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 456216 R-MMU-1855230 https://reactome.org/PathwayBrowser/#/R-MMU-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Mus musculus 456216 R-MMU-1855233 https://reactome.org/PathwayBrowser/#/R-MMU-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Mus musculus 456216 R-MMU-1861595 https://reactome.org/PathwayBrowser/#/R-MMU-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Mus musculus 456216 R-MMU-186786 https://reactome.org/PathwayBrowser/#/R-MMU-186786 Autophosphorylation of PDGF beta receptors IEA Mus musculus 456216 R-MMU-186800 https://reactome.org/PathwayBrowser/#/R-MMU-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-187520 https://reactome.org/PathwayBrowser/#/R-MMU-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Mus musculus 456216 R-MMU-187688 https://reactome.org/PathwayBrowser/#/R-MMU-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Mus musculus 456216 R-MMU-187916 https://reactome.org/PathwayBrowser/#/R-MMU-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Mus musculus 456216 R-MMU-187948 https://reactome.org/PathwayBrowser/#/R-MMU-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Mus musculus 456216 R-MMU-187949 https://reactome.org/PathwayBrowser/#/R-MMU-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Mus musculus 456216 R-MMU-187959 https://reactome.org/PathwayBrowser/#/R-MMU-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Mus musculus 456216 R-MMU-188350 https://reactome.org/PathwayBrowser/#/R-MMU-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Mus musculus 456216 R-MMU-188390 https://reactome.org/PathwayBrowser/#/R-MMU-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Mus musculus 456216 R-MMU-190326 https://reactome.org/PathwayBrowser/#/R-MMU-190326 Autocatalytic phosphorylation of FGFR4 IEA Mus musculus 456216 R-MMU-190385 https://reactome.org/PathwayBrowser/#/R-MMU-190385 Autocatalytic phosphorylation of FGFR3b IEA Mus musculus 456216 R-MMU-190388 https://reactome.org/PathwayBrowser/#/R-MMU-190388 Autocatalytic phosphorylation of FGFR3c IEA Mus musculus 456216 R-MMU-190408 https://reactome.org/PathwayBrowser/#/R-MMU-190408 Autocatalytic phosphorylation of FGFR2b IEA Mus musculus 456216 R-MMU-190413 https://reactome.org/PathwayBrowser/#/R-MMU-190413 Autocatalytic phosphorylation of FGFR2c IEA Mus musculus 456216 R-MMU-190427 https://reactome.org/PathwayBrowser/#/R-MMU-190427 Autocatalytic phosphorylation of FGFR1b IEA Mus musculus 456216 R-MMU-190429 https://reactome.org/PathwayBrowser/#/R-MMU-190429 Autocatalytic phosphorylation of FGFR1c IEA Mus musculus 456216 R-MMU-191062 https://reactome.org/PathwayBrowser/#/R-MMU-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Mus musculus 456216 R-MMU-191380 https://reactome.org/PathwayBrowser/#/R-MMU-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Mus musculus 456216 R-MMU-191414 https://reactome.org/PathwayBrowser/#/R-MMU-191414 MVD decarboxylates MVA5PP to IPPP IEA Mus musculus 456216 R-MMU-191422 https://reactome.org/PathwayBrowser/#/R-MMU-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Mus musculus 456216 R-MMU-191636 https://reactome.org/PathwayBrowser/#/R-MMU-191636 Phosphorylation of Cx43 by c-src IEA Mus musculus 456216 R-MMU-193362 https://reactome.org/PathwayBrowser/#/R-MMU-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-193703 https://reactome.org/PathwayBrowser/#/R-MMU-193703 IKKbeta is activated IEA Mus musculus 456216 R-MMU-193705 https://reactome.org/PathwayBrowser/#/R-MMU-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Mus musculus 456216 R-MMU-194153 https://reactome.org/PathwayBrowser/#/R-MMU-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-195275 https://reactome.org/PathwayBrowser/#/R-MMU-195275 Phosphorylation of APC component of the destruction complex IEA Mus musculus 456216 R-MMU-195283 https://reactome.org/PathwayBrowser/#/R-MMU-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Mus musculus 456216 R-MMU-195287 https://reactome.org/PathwayBrowser/#/R-MMU-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Mus musculus 456216 R-MMU-195300 https://reactome.org/PathwayBrowser/#/R-MMU-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Mus musculus 456216 R-MMU-195318 https://reactome.org/PathwayBrowser/#/R-MMU-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Mus musculus 456216 R-MMU-1963581 https://reactome.org/PathwayBrowser/#/R-MMU-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Mus musculus 456216 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 456216 R-MMU-1963586 https://reactome.org/PathwayBrowser/#/R-MMU-1963586 SRC family kinases phosphorylate ERBB2 IEA Mus musculus 456216 R-MMU-196773 https://reactome.org/PathwayBrowser/#/R-MMU-196773 COASY phosphorylates DP-CoA IEA Mus musculus 456216 R-MMU-196857 https://reactome.org/PathwayBrowser/#/R-MMU-196857 PANK2 phosphorylates PanK IEA Mus musculus 456216 R-MMU-196964 https://reactome.org/PathwayBrowser/#/R-MMU-196964 RFK:Mg2+ phosphorylates RIB IEA Mus musculus 456216 R-MMU-197198 https://reactome.org/PathwayBrowser/#/R-MMU-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Mus musculus 456216 R-MMU-197958 https://reactome.org/PathwayBrowser/#/R-MMU-197958 FPGS-2 transforms THF to THFPG IEA Mus musculus 456216 R-MMU-198263 https://reactome.org/PathwayBrowser/#/R-MMU-198263 NTRK1 phosphorylates IRS TAS Mus musculus 456216 R-MMU-198266 https://reactome.org/PathwayBrowser/#/R-MMU-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Mus musculus 456216 R-MMU-198314 https://reactome.org/PathwayBrowser/#/R-MMU-198314 DAG stimulates protein kinase C-delta IEA Mus musculus 456216 R-MMU-198599 https://reactome.org/PathwayBrowser/#/R-MMU-198599 AKT phosphorylates MDM2 IEA Mus musculus 456216 R-MMU-198609 https://reactome.org/PathwayBrowser/#/R-MMU-198609 AKT phosphorylates TSC2, inhibiting it IEA Mus musculus 456216 R-MMU-198611 https://reactome.org/PathwayBrowser/#/R-MMU-198611 AKT phosphorylates IKKalpha IEA Mus musculus 456216 R-MMU-198613 https://reactome.org/PathwayBrowser/#/R-MMU-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Mus musculus 456216 R-MMU-198621 https://reactome.org/PathwayBrowser/#/R-MMU-198621 AKT phosphorylates caspase-9 IEA Mus musculus 456216 R-MMU-198640 https://reactome.org/PathwayBrowser/#/R-MMU-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Mus musculus 456216 R-MMU-198669 https://reactome.org/PathwayBrowser/#/R-MMU-198669 p38MAPK phosphorylates MSK1 IEA Mus musculus 456216 R-MMU-198706 https://reactome.org/PathwayBrowser/#/R-MMU-198706 ERK1/2 activates ELK1 TAS Mus musculus 456216 R-MMU-198746 https://reactome.org/PathwayBrowser/#/R-MMU-198746 ERK1/2/5 activate RSK1/2/3 IEA Mus musculus 456216 R-MMU-198756 https://reactome.org/PathwayBrowser/#/R-MMU-198756 ERK1/2 phosphorylates MSK1 IEA Mus musculus 456216 R-MMU-199203 https://reactome.org/PathwayBrowser/#/R-MMU-199203 PANK1/3 phosphorylate PanK IEA Mus musculus 456216 R-MMU-199298 https://reactome.org/PathwayBrowser/#/R-MMU-199298 AKT phosphorylates CREB1 IEA Mus musculus 456216 R-MMU-199299 https://reactome.org/PathwayBrowser/#/R-MMU-199299 AKT phosphorylates FOXO transcription factors IEA Mus musculus 456216 R-MMU-199839 https://reactome.org/PathwayBrowser/#/R-MMU-199839 AKT can phosphorylate RSK IEA Mus musculus 456216 R-MMU-199863 https://reactome.org/PathwayBrowser/#/R-MMU-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Mus musculus 456216 R-MMU-199895 https://reactome.org/PathwayBrowser/#/R-MMU-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Mus musculus 456216 R-MMU-199910 https://reactome.org/PathwayBrowser/#/R-MMU-199910 MSK1 activates ATF1 IEA Mus musculus 456216 R-MMU-199917 https://reactome.org/PathwayBrowser/#/R-MMU-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Mus musculus 456216 R-MMU-199935 https://reactome.org/PathwayBrowser/#/R-MMU-199935 MSK1 activates CREB IEA Mus musculus 456216 R-MMU-200143 https://reactome.org/PathwayBrowser/#/R-MMU-200143 AKT phosphorylates AKT1S1 (PRAS40) IEA Mus musculus 456216 R-MMU-200318 https://reactome.org/PathwayBrowser/#/R-MMU-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Mus musculus 456216 R-MMU-200326 https://reactome.org/PathwayBrowser/#/R-MMU-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Mus musculus 456216 R-MMU-200421 https://reactome.org/PathwayBrowser/#/R-MMU-200421 Activation of cytosolic AMPK by phosphorylation IEA Mus musculus 456216 R-MMU-200423 https://reactome.org/PathwayBrowser/#/R-MMU-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Mus musculus 456216 R-MMU-200555 https://reactome.org/PathwayBrowser/#/R-MMU-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Mus musculus 456216 R-MMU-200681 https://reactome.org/PathwayBrowser/#/R-MMU-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Mus musculus 456216 R-MMU-200682 https://reactome.org/PathwayBrowser/#/R-MMU-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Mus musculus 456216 R-MMU-200711 https://reactome.org/PathwayBrowser/#/R-MMU-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Mus musculus 456216 R-MMU-201443 https://reactome.org/PathwayBrowser/#/R-MMU-201443 Type II receptor phosphorylates type I receptor IEA Mus musculus 456216 R-MMU-201476 https://reactome.org/PathwayBrowser/#/R-MMU-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Mus musculus 456216 R-MMU-201510 https://reactome.org/PathwayBrowser/#/R-MMU-201510 PI3K synthesizes PIP3 downstream of ALK IEA Mus musculus 456216 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 456216 R-MMU-201677 https://reactome.org/PathwayBrowser/#/R-MMU-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Mus musculus 456216 R-MMU-201717 https://reactome.org/PathwayBrowser/#/R-MMU-201717 CSNK2-mediated phosphorylation of DVL IEA Mus musculus 456216 R-MMU-202111 https://reactome.org/PathwayBrowser/#/R-MMU-202111 AKT1 phosphorylates eNOS IEA Mus musculus 456216 R-MMU-202165 https://reactome.org/PathwayBrowser/#/R-MMU-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Mus musculus 456216 R-MMU-202168 https://reactome.org/PathwayBrowser/#/R-MMU-202168 Phosphorylation of ZAP-70 by Lck IEA Mus musculus 456216 R-MMU-202174 https://reactome.org/PathwayBrowser/#/R-MMU-202174 Activation of ZAP-70 IEA Mus musculus 456216 R-MMU-202216 https://reactome.org/PathwayBrowser/#/R-MMU-202216 Phosphorylation of SLP-76 IEA Mus musculus 456216 R-MMU-202222 https://reactome.org/PathwayBrowser/#/R-MMU-202222 Phosphorylation of PKC theta IEA Mus musculus 456216 R-MMU-202233 https://reactome.org/PathwayBrowser/#/R-MMU-202233 Inactivation of Lck by Csk IEA Mus musculus 456216 R-MMU-202245 https://reactome.org/PathwayBrowser/#/R-MMU-202245 Phosphorylation of TBSMs in LAT IEA Mus musculus 456216 R-MMU-202248 https://reactome.org/PathwayBrowser/#/R-MMU-202248 Phosphorylation of PLC-gamma1 IEA Mus musculus 456216 R-MMU-202291 https://reactome.org/PathwayBrowser/#/R-MMU-202291 Activation of Lck IEA Mus musculus 456216 R-MMU-202307 https://reactome.org/PathwayBrowser/#/R-MMU-202307 Change of PKC theta conformation IEA Mus musculus 456216 R-MMU-202365 https://reactome.org/PathwayBrowser/#/R-MMU-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-202437 https://reactome.org/PathwayBrowser/#/R-MMU-202437 Phosphorylation of CARMA1 IEA Mus musculus 456216 R-MMU-202459 https://reactome.org/PathwayBrowser/#/R-MMU-202459 Phosphorylation of Bcl10 IEA Mus musculus 456216 R-MMU-202500 https://reactome.org/PathwayBrowser/#/R-MMU-202500 Activation of IKK complex IEA Mus musculus 456216 R-MMU-202510 https://reactome.org/PathwayBrowser/#/R-MMU-202510 Activation of TAK1-TAB2 complex IEA Mus musculus 456216 R-MMU-202541 https://reactome.org/PathwayBrowser/#/R-MMU-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Mus musculus 456216 R-MMU-2028284 https://reactome.org/PathwayBrowser/#/R-MMU-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Mus musculus 456216 R-MMU-2028555 https://reactome.org/PathwayBrowser/#/R-MMU-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Mus musculus 456216 R-MMU-2028583 https://reactome.org/PathwayBrowser/#/R-MMU-2028583 Phosphorylation of YAP by LATS2 IEA Mus musculus 456216 R-MMU-2028589 https://reactome.org/PathwayBrowser/#/R-MMU-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Mus musculus 456216 R-MMU-2028591 https://reactome.org/PathwayBrowser/#/R-MMU-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Mus musculus 456216 R-MMU-2028598 https://reactome.org/PathwayBrowser/#/R-MMU-2028598 Phosphorylation of YAP by LATS1 IEA Mus musculus 456216 R-MMU-2028629 https://reactome.org/PathwayBrowser/#/R-MMU-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Mus musculus 456216 R-MMU-2028635 https://reactome.org/PathwayBrowser/#/R-MMU-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Mus musculus 456216 R-MMU-2028661 https://reactome.org/PathwayBrowser/#/R-MMU-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Mus musculus 456216 R-MMU-2028670 https://reactome.org/PathwayBrowser/#/R-MMU-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Mus musculus 456216 R-MMU-2028673 https://reactome.org/PathwayBrowser/#/R-MMU-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Mus musculus 456216 R-MMU-2028675 https://reactome.org/PathwayBrowser/#/R-MMU-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Mus musculus 456216 R-MMU-2028679 https://reactome.org/PathwayBrowser/#/R-MMU-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Mus musculus 456216 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus 456216 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus 456216 R-MMU-2029454 https://reactome.org/PathwayBrowser/#/R-MMU-2029454 Autophosphorylation of PAK1 IEA Mus musculus 456216 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus 456216 R-MMU-2029460 https://reactome.org/PathwayBrowser/#/R-MMU-2029460 PAK1 phosphorylates LIMK1 IEA Mus musculus 456216 R-MMU-2029469 https://reactome.org/PathwayBrowser/#/R-MMU-2029469 p-ERK phosphorylates WAVEs and ABI IEA Mus musculus 456216 R-MMU-2029473 https://reactome.org/PathwayBrowser/#/R-MMU-2029473 Branching and elongation of mother and daughter filaments IEA Mus musculus 456216 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus 456216 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 456216 R-MMU-2046087 https://reactome.org/PathwayBrowser/#/R-MMU-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Mus musculus 456216 R-MMU-2046093 https://reactome.org/PathwayBrowser/#/R-MMU-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Mus musculus 456216 R-MMU-205060 https://reactome.org/PathwayBrowser/#/R-MMU-205060 NRIF and TRAF6 may activate JNK TAS Mus musculus 456216 R-MMU-205075 https://reactome.org/PathwayBrowser/#/R-MMU-205075 JNK phosphorylates BIM, BAD and other targets IEA Mus musculus 456216 R-MMU-205136 https://reactome.org/PathwayBrowser/#/R-MMU-205136 GTP-bound RAC contributes to JNK activation IEA Mus musculus 456216 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 456216 R-MMU-2060328 https://reactome.org/PathwayBrowser/#/R-MMU-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Mus musculus 456216 R-MMU-209087 https://reactome.org/PathwayBrowser/#/R-MMU-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Mus musculus 456216 R-MMU-209329 https://reactome.org/PathwayBrowser/#/R-MMU-209329 Murine MKK4 kinase is phosphorylated and activated by Phospho TAK1:Phospho TAB1:Phospho TAB2 kinase complex TAS Mus musculus 456216 R-MMU-210291 https://reactome.org/PathwayBrowser/#/R-MMU-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Mus musculus 456216 R-MMU-211119 https://reactome.org/PathwayBrowser/#/R-MMU-211119 Trans-phosphorylation of Tie2 TAS Mus musculus 456216 R-MMU-211164 https://reactome.org/PathwayBrowser/#/R-MMU-211164 AKT phosphorylates FOXO1A IEA Mus musculus 456216 R-MMU-212710 https://reactome.org/PathwayBrowser/#/R-MMU-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Mus musculus 456216 R-MMU-2130194 https://reactome.org/PathwayBrowser/#/R-MMU-2130194 ABL phosphorylates WAVEs IEA Mus musculus 456216 R-MMU-2161526 https://reactome.org/PathwayBrowser/#/R-MMU-2161526 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 456216 R-MMU-2161533 https://reactome.org/PathwayBrowser/#/R-MMU-2161533 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 456216 R-MMU-216723 https://reactome.org/PathwayBrowser/#/R-MMU-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Mus musculus 456216 R-MMU-216757 https://reactome.org/PathwayBrowser/#/R-MMU-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Mus musculus 456216 R-MMU-2168079 https://reactome.org/PathwayBrowser/#/R-MMU-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Mus musculus 456216 R-MMU-2176475 https://reactome.org/PathwayBrowser/#/R-MMU-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Mus musculus 456216 R-MMU-2197690 https://reactome.org/PathwayBrowser/#/R-MMU-2197690 Detachment of WASP/WAVE IEA Mus musculus 456216 R-MMU-2197698 https://reactome.org/PathwayBrowser/#/R-MMU-2197698 Src phosphorylate WASP,N-WASP IEA Mus musculus 456216 R-MMU-2213248 https://reactome.org/PathwayBrowser/#/R-MMU-2213248 Transport of antigen loaded MHC II molecules to surface IEA Mus musculus 456216 R-MMU-2214351 https://reactome.org/PathwayBrowser/#/R-MMU-2214351 PLK1 phosphorylates GORASP1 IEA Mus musculus 456216 R-MMU-2267372 https://reactome.org/PathwayBrowser/#/R-MMU-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Mus musculus 456216 R-MMU-2294580 https://reactome.org/PathwayBrowser/#/R-MMU-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Mus musculus 456216 R-MMU-2294600 https://reactome.org/PathwayBrowser/#/R-MMU-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Mus musculus 456216 R-MMU-2316348 https://reactome.org/PathwayBrowser/#/R-MMU-2316348 RalA:GTP binds Myo1c:Calm1 and F-actin TAS Mus musculus 456216 R-MMU-2316351 https://reactome.org/PathwayBrowser/#/R-MMU-2316351 Translocation of Glut4 Vesicle and Docking at the Plasma Membrane TAS Mus musculus 456216 R-MMU-2316434 https://reactome.org/PathwayBrowser/#/R-MMU-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-2395412 https://reactome.org/PathwayBrowser/#/R-MMU-2395412 Phosphorylation of SYK IEA Mus musculus 456216 R-MMU-2395436 https://reactome.org/PathwayBrowser/#/R-MMU-2395436 Phosphorylation of DAP12 TAS Mus musculus 456216 R-MMU-2395801 https://reactome.org/PathwayBrowser/#/R-MMU-2395801 Phosphorylation of LAT by p-SYK IEA Mus musculus 456216 R-MMU-2396002 https://reactome.org/PathwayBrowser/#/R-MMU-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex IEA Mus musculus 456216 R-MMU-2396007 https://reactome.org/PathwayBrowser/#/R-MMU-2396007 IRF3 is phosphorylated by TBK1 IEA Mus musculus 456216 R-MMU-2396594 https://reactome.org/PathwayBrowser/#/R-MMU-2396594 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus 456216 R-MMU-2404193 https://reactome.org/PathwayBrowser/#/R-MMU-2404193 IGF1R phosphorylates SHC1 IEA Mus musculus 456216 R-MMU-2404199 https://reactome.org/PathwayBrowser/#/R-MMU-2404199 IGF1,2:IGF1R autophosphorylates IEA Mus musculus 456216 R-MMU-2408505 https://reactome.org/PathwayBrowser/#/R-MMU-2408505 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by Pstk TAS Mus musculus 456216 R-MMU-2422927 https://reactome.org/PathwayBrowser/#/R-MMU-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Mus musculus 456216 R-MMU-2424480 https://reactome.org/PathwayBrowser/#/R-MMU-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-2424484 https://reactome.org/PathwayBrowser/#/R-MMU-2424484 Phosphorylation of BTK by p-SYK IEA Mus musculus 456216 R-MMU-2424486 https://reactome.org/PathwayBrowser/#/R-MMU-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Mus musculus 456216 R-MMU-2424487 https://reactome.org/PathwayBrowser/#/R-MMU-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Mus musculus 456216 R-MMU-2428926 https://reactome.org/PathwayBrowser/#/R-MMU-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Mus musculus 456216 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus 456216 R-MMU-2466068 https://reactome.org/PathwayBrowser/#/R-MMU-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Mus musculus 456216 R-MMU-2468287 https://reactome.org/PathwayBrowser/#/R-MMU-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Mus musculus 456216 R-MMU-2468293 https://reactome.org/PathwayBrowser/#/R-MMU-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Mus musculus 456216 R-MMU-2470487 https://reactome.org/PathwayBrowser/#/R-MMU-2470487 Acvr2a phosphorylates Acvr1c in response to Activin TAS Mus musculus 456216 R-MMU-2529020 https://reactome.org/PathwayBrowser/#/R-MMU-2529020 CK2 phosphorylates condensin I subunits IEA Mus musculus 456216 R-MMU-2562526 https://reactome.org/PathwayBrowser/#/R-MMU-2562526 PLK1 phosphorylates OPTN IEA Mus musculus 456216 R-MMU-2574840 https://reactome.org/PathwayBrowser/#/R-MMU-2574840 AJUBA facilitates AURKA autophosphorylation IEA Mus musculus 456216 R-MMU-2581474 https://reactome.org/PathwayBrowser/#/R-MMU-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Mus musculus 456216 R-MMU-2586548 https://reactome.org/PathwayBrowser/#/R-MMU-2586548 Jak2 Autophosphorylates in Response to Leptin TAS Mus musculus 456216 R-MMU-2586557 https://reactome.org/PathwayBrowser/#/R-MMU-2586557 Jak2 Phosphorylates Lepr TAS Mus musculus 456216 R-MMU-265682 https://reactome.org/PathwayBrowser/#/R-MMU-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Mus musculus 456216 R-MMU-265783 https://reactome.org/PathwayBrowser/#/R-MMU-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-266082 https://reactome.org/PathwayBrowser/#/R-MMU-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Mus musculus 456216 R-MMU-2671740 https://reactome.org/PathwayBrowser/#/R-MMU-2671740 Jak2 Phosphorylates Shp2 in Response to Leptin TAS Mus musculus 456216 R-MMU-2671830 https://reactome.org/PathwayBrowser/#/R-MMU-2671830 Jak2 Phosphorylates Irs1/2 in Response to Leptin TAS Mus musculus 456216 R-MMU-2671836 https://reactome.org/PathwayBrowser/#/R-MMU-2671836 Jak2 Phosphorylates Stat3 in Response to Leptin TAS Mus musculus 456216 R-MMU-2671843 https://reactome.org/PathwayBrowser/#/R-MMU-2671843 Jak2 Phosphorylates Stat5 in Response to Leptin TAS Mus musculus 456216 R-MMU-2682349 https://reactome.org/PathwayBrowser/#/R-MMU-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Mus musculus 456216 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus 456216 R-MMU-2730835 https://reactome.org/PathwayBrowser/#/R-MMU-2730835 Autophosphorylation of PKC-theta IEA Mus musculus 456216 R-MMU-2730841 https://reactome.org/PathwayBrowser/#/R-MMU-2730841 Phosphorylation and activation of VAV IEA Mus musculus 456216 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus 456216 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus 456216 R-MMU-2730856 https://reactome.org/PathwayBrowser/#/R-MMU-2730856 Autophosphorylation of PAK IEA Mus musculus 456216 R-MMU-2730858 https://reactome.org/PathwayBrowser/#/R-MMU-2730858 Autophosphorylation of BTK/ITK IEA Mus musculus 456216 R-MMU-2730862 https://reactome.org/PathwayBrowser/#/R-MMU-2730862 Autophosphorylation of LYN kinase IEA Mus musculus 456216 R-MMU-2730863 https://reactome.org/PathwayBrowser/#/R-MMU-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Mus musculus 456216 R-MMU-2730868 https://reactome.org/PathwayBrowser/#/R-MMU-2730868 Phosphorylation of MEK7 by MEKK1 IEA Mus musculus 456216 R-MMU-2730869 https://reactome.org/PathwayBrowser/#/R-MMU-2730869 Phosphorylation of Gab2 by Syk/Fyn TAS Mus musculus 456216 R-MMU-2730870 https://reactome.org/PathwayBrowser/#/R-MMU-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Mus musculus 456216 R-MMU-2730876 https://reactome.org/PathwayBrowser/#/R-MMU-2730876 Phosphorylation of IKK-beta by TAK1 IEA Mus musculus 456216 R-MMU-2730880 https://reactome.org/PathwayBrowser/#/R-MMU-2730880 Autophosphorylation and activation of Mekk1 TAS Mus musculus 456216 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus 456216 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus 456216 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus 456216 R-MMU-2730896 https://reactome.org/PathwayBrowser/#/R-MMU-2730896 Phosphorylation of MEK4 by MEKK1 IEA Mus musculus 456216 R-MMU-2730900 https://reactome.org/PathwayBrowser/#/R-MMU-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Mus musculus 456216 R-MMU-2984220 https://reactome.org/PathwayBrowser/#/R-MMU-2984220 CDK1:CCNB phosphorylates NEK9 IEA Mus musculus 456216 R-MMU-2984226 https://reactome.org/PathwayBrowser/#/R-MMU-2984226 PLK1 phosphorylates NEK9 IEA Mus musculus 456216 R-MMU-2990882 https://reactome.org/PathwayBrowser/#/R-MMU-2990882 CDK1 phosphorylates NUP98 IEA Mus musculus 456216 R-MMU-2993898 https://reactome.org/PathwayBrowser/#/R-MMU-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Mus musculus 456216 R-MMU-3000310 https://reactome.org/PathwayBrowser/#/R-MMU-3000310 AURKA phosphorylates PLK1 IEA Mus musculus 456216 R-MMU-3000327 https://reactome.org/PathwayBrowser/#/R-MMU-3000327 PLK1 phosphorylates BORA IEA Mus musculus 456216 R-MMU-3095901 https://reactome.org/PathwayBrowser/#/R-MMU-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Mus musculus 456216 R-MMU-3132737 https://reactome.org/PathwayBrowser/#/R-MMU-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Mus musculus 456216 R-MMU-3222006 https://reactome.org/PathwayBrowser/#/R-MMU-3222006 STK11 (LKB1) phosphorylates NUAK1 IEA Mus musculus 456216 R-MMU-3222020 https://reactome.org/PathwayBrowser/#/R-MMU-3222020 NUAK1 phosphorylates TP53 IEA Mus musculus 456216 R-MMU-3228469 https://reactome.org/PathwayBrowser/#/R-MMU-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Mus musculus 456216 R-MMU-3238999 https://reactome.org/PathwayBrowser/#/R-MMU-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Mus musculus 456216 R-MMU-3239014 https://reactome.org/PathwayBrowser/#/R-MMU-3239014 MAPKAPK5 phosphorylates TP53 IEA Mus musculus 456216 R-MMU-3239019 https://reactome.org/PathwayBrowser/#/R-MMU-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Mus musculus 456216 R-MMU-3249371 https://reactome.org/PathwayBrowser/#/R-MMU-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Mus musculus 456216 R-MMU-3249379 https://reactome.org/PathwayBrowser/#/R-MMU-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Mus musculus 456216 R-MMU-3249390 https://reactome.org/PathwayBrowser/#/R-MMU-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Mus musculus 456216 R-MMU-3371422 https://reactome.org/PathwayBrowser/#/R-MMU-3371422 ATP hydrolysis by HSP70 IEA Mus musculus 456216 R-MMU-3371435 https://reactome.org/PathwayBrowser/#/R-MMU-3371435 Constitutive phosphorylation by GSK3 IEA Mus musculus 456216 R-MMU-3371503 https://reactome.org/PathwayBrowser/#/R-MMU-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Mus musculus 456216 R-MMU-3371531 https://reactome.org/PathwayBrowser/#/R-MMU-3371531 Constitutive phosphorylation by pERK1/2 IEA Mus musculus 456216 R-MMU-349426 https://reactome.org/PathwayBrowser/#/R-MMU-349426 Phosphorylation of MDM4 by CHEK2 IEA Mus musculus 456216 R-MMU-349444 https://reactome.org/PathwayBrowser/#/R-MMU-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Mus musculus 456216 R-MMU-349455 https://reactome.org/PathwayBrowser/#/R-MMU-349455 Phosphorylation of MDM4 by ATM IEA Mus musculus 456216 R-MMU-354073 https://reactome.org/PathwayBrowser/#/R-MMU-354073 Autophosphorylation of PTK2 at Y397 IEA Mus musculus 456216 R-MMU-354124 https://reactome.org/PathwayBrowser/#/R-MMU-354124 Phosphorylation of pPTK2 by SRC IEA Mus musculus 456216 R-MMU-3697899 https://reactome.org/PathwayBrowser/#/R-MMU-3697899 Atp7a transfers Cu from Atox1 to Sod3 TAS Mus musculus 456216 R-MMU-372693 https://reactome.org/PathwayBrowser/#/R-MMU-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Mus musculus 456216 R-MMU-373747 https://reactome.org/PathwayBrowser/#/R-MMU-373747 Phosphorylation of nephrin by FYN IEA Mus musculus 456216 R-MMU-373750 https://reactome.org/PathwayBrowser/#/R-MMU-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Mus musculus 456216 R-MMU-374664 https://reactome.org/PathwayBrowser/#/R-MMU-374664 Phosphorylation and activation of Ezrin IEA Mus musculus 456216 R-MMU-374701 https://reactome.org/PathwayBrowser/#/R-MMU-374701 Phosphorylation of DCC by Fyn IEA Mus musculus 456216 R-MMU-3769394 https://reactome.org/PathwayBrowser/#/R-MMU-3769394 AKT phosphorylates CBY1 IEA Mus musculus 456216 R-MMU-377186 https://reactome.org/PathwayBrowser/#/R-MMU-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Mus musculus 456216 R-MMU-3772435 https://reactome.org/PathwayBrowser/#/R-MMU-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Mus musculus 456216 R-MMU-3772436 https://reactome.org/PathwayBrowser/#/R-MMU-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Mus musculus 456216 R-MMU-377640 https://reactome.org/PathwayBrowser/#/R-MMU-377640 Autophosphorylation of SRC IEA Mus musculus 456216 R-MMU-3788705 https://reactome.org/PathwayBrowser/#/R-MMU-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Mus musculus 456216 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 456216 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 456216 R-MMU-380272 https://reactome.org/PathwayBrowser/#/R-MMU-380272 Plk1-mediated phosphorylation of Nlp IEA Mus musculus 456216 R-MMU-380278 https://reactome.org/PathwayBrowser/#/R-MMU-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Mus musculus 456216 R-MMU-380780 https://reactome.org/PathwayBrowser/#/R-MMU-380780 Activation of Src IEA Mus musculus 456216 R-MMU-380927 https://reactome.org/PathwayBrowser/#/R-MMU-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Mus musculus 456216 R-MMU-381091 https://reactome.org/PathwayBrowser/#/R-MMU-381091 IRE1 dimer autophosphorylates IEA Mus musculus 456216 R-MMU-381111 https://reactome.org/PathwayBrowser/#/R-MMU-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Mus musculus 456216 R-MMU-382553 https://reactome.org/PathwayBrowser/#/R-MMU-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Mus musculus 456216 R-MMU-382560 https://reactome.org/PathwayBrowser/#/R-MMU-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Mus musculus 456216 R-MMU-382575 https://reactome.org/PathwayBrowser/#/R-MMU-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Mus musculus 456216 R-MMU-383190 https://reactome.org/PathwayBrowser/#/R-MMU-383190 HCO3- transport through ion channel IEA Mus musculus 456216 R-MMU-3857329 https://reactome.org/PathwayBrowser/#/R-MMU-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Mus musculus 456216 R-MMU-388831 https://reactome.org/PathwayBrowser/#/R-MMU-388831 Phosphorylation of CD28 IEA Mus musculus 456216 R-MMU-388833 https://reactome.org/PathwayBrowser/#/R-MMU-388833 Phosphorylation of CTLA-4 IEA Mus musculus 456216 R-MMU-389083 https://reactome.org/PathwayBrowser/#/R-MMU-389083 Autophosphorylation of PDGF alpha receptors IEA Mus musculus 456216 R-MMU-389086 https://reactome.org/PathwayBrowser/#/R-MMU-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Mus musculus 456216 R-MMU-389158 https://reactome.org/PathwayBrowser/#/R-MMU-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-389354 https://reactome.org/PathwayBrowser/#/R-MMU-389354 Activation of Vav1 IEA Mus musculus 456216 R-MMU-389756 https://reactome.org/PathwayBrowser/#/R-MMU-389756 AKT interacts and phosphorylates Cot IEA Mus musculus 456216 R-MMU-389762 https://reactome.org/PathwayBrowser/#/R-MMU-389762 Phosphorylation of PD-1 IEA Mus musculus 456216 R-MMU-390593 https://reactome.org/PathwayBrowser/#/R-MMU-390593 ATP Hydrolysis By Myosin IEA Mus musculus 456216 R-MMU-390597 https://reactome.org/PathwayBrowser/#/R-MMU-390597 Release Of ADP From Myosin IEA Mus musculus 456216 R-MMU-391266 https://reactome.org/PathwayBrowser/#/R-MMU-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Mus musculus 456216 R-MMU-392187 https://reactome.org/PathwayBrowser/#/R-MMU-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Mus musculus 456216 R-MMU-392195 https://reactome.org/PathwayBrowser/#/R-MMU-392195 Gi activation by P2Y purinoceptor 12 IEA Mus musculus 456216 R-MMU-392202 https://reactome.org/PathwayBrowser/#/R-MMU-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Mus musculus 456216 R-MMU-392300 https://reactome.org/PathwayBrowser/#/R-MMU-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-392530 https://reactome.org/PathwayBrowser/#/R-MMU-392530 p-S400-Cot phosphorylates NIK IEA Mus musculus 456216 R-MMU-392752 https://reactome.org/PathwayBrowser/#/R-MMU-392752 Phosphorylation of L1 by CK-II IEA Mus musculus 456216 R-MMU-3928578 https://reactome.org/PathwayBrowser/#/R-MMU-3928578 EPH receptors autophosphorylate IEA Mus musculus 456216 R-MMU-3928599 https://reactome.org/PathwayBrowser/#/R-MMU-3928599 Ptk2 autophosphorylates at Y397 TAS Mus musculus 456216 R-MMU-3928604 https://reactome.org/PathwayBrowser/#/R-MMU-3928604 SFKs phosphorylate VAV2,3 IEA Mus musculus 456216 R-MMU-3928613 https://reactome.org/PathwayBrowser/#/R-MMU-3928613 Fyn phosphorylates Nmdar2b TAS Mus musculus 456216 R-MMU-3928620 https://reactome.org/PathwayBrowser/#/R-MMU-3928620 PAK1 autophosphorylates IEA Mus musculus 456216 R-MMU-3928622 https://reactome.org/PathwayBrowser/#/R-MMU-3928622 SFKs phosphorylate Git1 TAS Mus musculus 456216 R-MMU-3928625 https://reactome.org/PathwayBrowser/#/R-MMU-3928625 PAKs autophosphorylate IEA Mus musculus 456216 R-MMU-3928627 https://reactome.org/PathwayBrowser/#/R-MMU-3928627 EPHB phosphorylates TIAM1 IEA Mus musculus 456216 R-MMU-399939 https://reactome.org/PathwayBrowser/#/R-MMU-399939 Autophosphorylation of PAK IEA Mus musculus 456216 R-MMU-399944 https://reactome.org/PathwayBrowser/#/R-MMU-399944 Phosphorylation of CRMPs by Cdk5 IEA Mus musculus 456216 R-MMU-399947 https://reactome.org/PathwayBrowser/#/R-MMU-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Mus musculus 456216 R-MMU-399951 https://reactome.org/PathwayBrowser/#/R-MMU-399951 Phosphorylation of CRMPs by GSK3beta IEA Mus musculus 456216 R-MMU-399952 https://reactome.org/PathwayBrowser/#/R-MMU-399952 Phosphorylation of LIMK-1 by PAK IEA Mus musculus 456216 R-MMU-399978 https://reactome.org/PathwayBrowser/#/R-MMU-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Mus musculus 456216 R-MMU-4085028 https://reactome.org/PathwayBrowser/#/R-MMU-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Mus musculus 456216 R-MMU-4086410 https://reactome.org/PathwayBrowser/#/R-MMU-4086410 CDK1 phosphorylates BORA IEA Mus musculus 456216 R-MMU-4088024 https://reactome.org/PathwayBrowser/#/R-MMU-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Mus musculus 456216 R-MMU-4088134 https://reactome.org/PathwayBrowser/#/R-MMU-4088134 PLK1 phosphorylates FOXM1 IEA Mus musculus 456216 R-MMU-4093332 https://reactome.org/PathwayBrowser/#/R-MMU-4093332 p-EPHB phosphorylates SDC2 IEA Mus musculus 456216 R-MMU-416320 https://reactome.org/PathwayBrowser/#/R-MMU-416320 Trafficking of GluR1-containing AMPA receptors IEA Mus musculus 456216 R-MMU-416639 https://reactome.org/PathwayBrowser/#/R-MMU-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Mus musculus 456216 R-MMU-416985 https://reactome.org/PathwayBrowser/#/R-MMU-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Mus musculus 456216 R-MMU-417829 https://reactome.org/PathwayBrowser/#/R-MMU-417829 P2RY12 binds ADP IEA Mus musculus 456216 R-MMU-417843 https://reactome.org/PathwayBrowser/#/R-MMU-417843 P2Y13 binds ADP IEA Mus musculus 456216 R-MMU-417908 https://reactome.org/PathwayBrowser/#/R-MMU-417908 P2RY1 binds ADP IEA Mus musculus 456216 R-MMU-418576 https://reactome.org/PathwayBrowser/#/R-MMU-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Mus musculus 456216 R-MMU-418845 https://reactome.org/PathwayBrowser/#/R-MMU-418845 Activation of caspase-3 IEA Mus musculus 456216 R-MMU-418870 https://reactome.org/PathwayBrowser/#/R-MMU-418870 Phosphorylation of Unc5C TAS Mus musculus 456216 R-MMU-419644 https://reactome.org/PathwayBrowser/#/R-MMU-419644 Transphosphorylation of pLIMK1 IEA Mus musculus 456216 R-MMU-419646 https://reactome.org/PathwayBrowser/#/R-MMU-419646 SEMA4D interacts with Plexin-B1:Met IEA Mus musculus 456216 R-MMU-420382 https://reactome.org/PathwayBrowser/#/R-MMU-420382 Phosphorylation of FAK by Src kinases TAS Mus musculus 456216 R-MMU-420394 https://reactome.org/PathwayBrowser/#/R-MMU-420394 Recruitment of FAK to NCAM1:Fyn in lipid rafts TAS Mus musculus 456216 R-MMU-421007 https://reactome.org/PathwayBrowser/#/R-MMU-421007 Endocytosis of Ca impermeable AMPA receptors IEA Mus musculus 456216 R-MMU-421143 https://reactome.org/PathwayBrowser/#/R-MMU-421143 Phosphorylation of Plexin-A TAS Mus musculus 456216 R-MMU-421694 https://reactome.org/PathwayBrowser/#/R-MMU-421694 Phosphorylation of FADK1 TAS Mus musculus 456216 R-MMU-421836 https://reactome.org/PathwayBrowser/#/R-MMU-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Mus musculus 456216 R-MMU-426240 https://reactome.org/PathwayBrowser/#/R-MMU-426240 DAG kinase produces phosphatidic acid from DAG IEA Mus musculus 456216 R-MMU-428273 https://reactome.org/PathwayBrowser/#/R-MMU-428273 SPHK1 phosphorylates sphingoid IEA Mus musculus 456216 R-MMU-428888 https://reactome.org/PathwayBrowser/#/R-MMU-428888 Phosphorylation of ROBO1 by ABL kinase IEA Mus musculus 456216 R-MMU-428941 https://reactome.org/PathwayBrowser/#/R-MMU-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Mus musculus 456216 R-MMU-428961 https://reactome.org/PathwayBrowser/#/R-MMU-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Mus musculus 456216 R-MMU-429016 https://reactome.org/PathwayBrowser/#/R-MMU-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Mus musculus 456216 R-MMU-429157 https://reactome.org/PathwayBrowser/#/R-MMU-429157 ABCC4 accumulation of dense granule contents IEA Mus musculus 456216 R-MMU-429441 https://reactome.org/PathwayBrowser/#/R-MMU-429441 SYK activation by SRC IEA Mus musculus 456216 R-MMU-429449 https://reactome.org/PathwayBrowser/#/R-MMU-429449 Syk activation leads to SLP-76 activation IEA Mus musculus 456216 R-MMU-432129 https://reactome.org/PathwayBrowser/#/R-MMU-432129 FGR binds and phosphorylates LRP8 IEA Mus musculus 456216 R-MMU-432148 https://reactome.org/PathwayBrowser/#/R-MMU-432148 Fgr may phosphorylate p38 MAPK IEA Mus musculus 456216 R-MMU-432232 https://reactome.org/PathwayBrowser/#/R-MMU-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Mus musculus 456216 R-MMU-432688 https://reactome.org/PathwayBrowser/#/R-MMU-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating IEA Mus musculus 456216 R-MMU-4332358 https://reactome.org/PathwayBrowser/#/R-MMU-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Mus musculus 456216 R-MMU-4332363 https://reactome.org/PathwayBrowser/#/R-MMU-4332363 Autophosphorylation and activation of CAMK2 IEA Mus musculus 456216 R-MMU-434836 https://reactome.org/PathwayBrowser/#/R-MMU-434836 Syk/Lck phosphorylate LAT IEA Mus musculus 456216 R-MMU-435244 https://reactome.org/PathwayBrowser/#/R-MMU-435244 PECAM1 is phosphorylated IEA Mus musculus 456216 R-MMU-437162 https://reactome.org/PathwayBrowser/#/R-MMU-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-4411383 https://reactome.org/PathwayBrowser/#/R-MMU-4411383 NLK phosphorylates TCF/LEF IEA Mus musculus 456216 R-MMU-4411402 https://reactome.org/PathwayBrowser/#/R-MMU-4411402 Activation of NLK IEA Mus musculus 456216 R-MMU-4420117 https://reactome.org/PathwayBrowser/#/R-MMU-4420117 VEGFR2 autophosphorylates IEA Mus musculus 456216 R-MMU-4420121 https://reactome.org/PathwayBrowser/#/R-MMU-4420121 SFKs phosphorylate PLCG1 IEA Mus musculus 456216 R-MMU-4420128 https://reactome.org/PathwayBrowser/#/R-MMU-4420128 SRC-1 phosphorylates SHB IEA Mus musculus 456216 R-MMU-4420206 https://reactome.org/PathwayBrowser/#/R-MMU-4420206 Phosphorylation of SRC-1 IEA Mus musculus 456216 R-MMU-442724 https://reactome.org/PathwayBrowser/#/R-MMU-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Mus musculus 456216 R-MMU-442749 https://reactome.org/PathwayBrowser/#/R-MMU-442749 CaMKK autophosphorylates in the nucleus IEA Mus musculus 456216 R-MMU-445072 https://reactome.org/PathwayBrowser/#/R-MMU-445072 Interaction of PAK1 with Rac1-GTP IEA Mus musculus 456216 R-MMU-445075 https://reactome.org/PathwayBrowser/#/R-MMU-445075 CHL1 interacts with Hsc70 TAS Mus musculus 456216 R-MMU-445079 https://reactome.org/PathwayBrowser/#/R-MMU-445079 Phosphorylation of L1 by ERK IEA Mus musculus 456216 R-MMU-445084 https://reactome.org/PathwayBrowser/#/R-MMU-445084 Phosphorylation of L1 by SRC IEA Mus musculus 456216 R-MMU-445699 https://reactome.org/PathwayBrowser/#/R-MMU-445699 ATP Hydrolysis By Myosin IEA Mus musculus 456216 R-MMU-445705 https://reactome.org/PathwayBrowser/#/R-MMU-445705 Release Of ADP From Myosin IEA Mus musculus 456216 R-MMU-445813 https://reactome.org/PathwayBrowser/#/R-MMU-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Mus musculus 456216 R-MMU-446634 https://reactome.org/PathwayBrowser/#/R-MMU-446634 IRAK4 is activated by autophosphorylation IEA Mus musculus 456216 R-MMU-446694 https://reactome.org/PathwayBrowser/#/R-MMU-446694 IRAK4 phosphorylates IRAK1 IEA Mus musculus 456216 R-MMU-446701 https://reactome.org/PathwayBrowser/#/R-MMU-446701 IRAK4-activated IRAK1 autophosphorylates IEA Mus musculus 456216 R-MMU-447074 https://reactome.org/PathwayBrowser/#/R-MMU-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Mus musculus 456216 R-MMU-448953 https://reactome.org/PathwayBrowser/#/R-MMU-448953 Phosphorylation of E47 by p38 MAPK TAS Mus musculus 456216 R-MMU-448955 https://reactome.org/PathwayBrowser/#/R-MMU-448955 Phosphorylation of MEF2 proteins by p38 IEA Mus musculus 456216 R-MMU-448961 https://reactome.org/PathwayBrowser/#/R-MMU-448961 Activation of p38 alpha/beta MAPK TAS Mus musculus 456216 R-MMU-450222 https://reactome.org/PathwayBrowser/#/R-MMU-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Mus musculus 456216 R-MMU-450325 https://reactome.org/PathwayBrowser/#/R-MMU-450325 c-FOS activation by phospho ERK1/2 IEA Mus musculus 456216 R-MMU-450333 https://reactome.org/PathwayBrowser/#/R-MMU-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Mus musculus 456216 R-MMU-450337 https://reactome.org/PathwayBrowser/#/R-MMU-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Mus musculus 456216 R-MMU-450346 https://reactome.org/PathwayBrowser/#/R-MMU-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Mus musculus 456216 R-MMU-450463 https://reactome.org/PathwayBrowser/#/R-MMU-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Mus musculus 456216 R-MMU-450474 https://reactome.org/PathwayBrowser/#/R-MMU-450474 MK2 phosphorylates BRF1 IEA Mus musculus 456216 R-MMU-450490 https://reactome.org/PathwayBrowser/#/R-MMU-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Mus musculus 456216 R-MMU-450499 https://reactome.org/PathwayBrowser/#/R-MMU-450499 Protein Kinase B (AKT) phosphorylates KSRP IEA Mus musculus 456216 R-MMU-450533 https://reactome.org/PathwayBrowser/#/R-MMU-450533 PKCdelta phosphorylates HuR IEA Mus musculus 456216 R-MMU-450550 https://reactome.org/PathwayBrowser/#/R-MMU-450550 PKCalpha phosphorylates HuR IEA Mus musculus 456216 R-MMU-450827 https://reactome.org/PathwayBrowser/#/R-MMU-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Mus musculus 456216 R-MMU-451204 https://reactome.org/PathwayBrowser/#/R-MMU-451204 Phosphorylation of Khsrp by p38 TAS Mus musculus 456216 R-MMU-451942 https://reactome.org/PathwayBrowser/#/R-MMU-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Mus musculus 456216 R-MMU-452097 https://reactome.org/PathwayBrowser/#/R-MMU-452097 Recruited STAT5 is phosphorylated IEA Mus musculus 456216 R-MMU-452100 https://reactome.org/PathwayBrowser/#/R-MMU-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Mus musculus 456216 R-MMU-452122 https://reactome.org/PathwayBrowser/#/R-MMU-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Mus musculus 456216 R-MMU-453200 https://reactome.org/PathwayBrowser/#/R-MMU-453200 SYK autophosphorylates IEA Mus musculus 456216 R-MMU-4551572 https://reactome.org/PathwayBrowser/#/R-MMU-4551572 Vangl2 is phosphorylated in response to Wnt5a TAS Mus musculus 456216 R-MMU-4793911 https://reactome.org/PathwayBrowser/#/R-MMU-4793911 MAPKAPK2 phosphorylates HSF1 IEA Mus musculus 456216 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 456216 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 456216 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 456216 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 456216 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 456216 R-MMU-504054 https://reactome.org/PathwayBrowser/#/R-MMU-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Mus musculus 456216 R-MMU-508040 https://reactome.org/PathwayBrowser/#/R-MMU-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Mus musculus 456216 R-MMU-5082387 https://reactome.org/PathwayBrowser/#/R-MMU-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Mus musculus 456216 R-MMU-5082405 https://reactome.org/PathwayBrowser/#/R-MMU-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Mus musculus 456216 R-MMU-508282 https://reactome.org/PathwayBrowser/#/R-MMU-508282 SYK is a substrate for JAK1 IEA Mus musculus 456216 R-MMU-508308 https://reactome.org/PathwayBrowser/#/R-MMU-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Mus musculus 456216 R-MMU-5138432 https://reactome.org/PathwayBrowser/#/R-MMU-5138432 DVL2 is phosphorylated by PKC IEA Mus musculus 456216 R-MMU-5195402 https://reactome.org/PathwayBrowser/#/R-MMU-5195402 CDK1 phosphorylates LPIN IEA Mus musculus 456216 R-MMU-5213464 https://reactome.org/PathwayBrowser/#/R-MMU-5213464 RIPK1 is phosphorylated IEA Mus musculus 456216 R-MMU-5213466 https://reactome.org/PathwayBrowser/#/R-MMU-5213466 RIPK3 is phosphorylated IEA Mus musculus 456216 R-MMU-5218640 https://reactome.org/PathwayBrowser/#/R-MMU-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Mus musculus 456216 R-MMU-5218642 https://reactome.org/PathwayBrowser/#/R-MMU-5218642 PTK2 autophosphorylates IEA Mus musculus 456216 R-MMU-5218804 https://reactome.org/PathwayBrowser/#/R-MMU-5218804 p38 MAPK activation by VEGFR IEA Mus musculus 456216 R-MMU-5218805 https://reactome.org/PathwayBrowser/#/R-MMU-5218805 PKC autophosphorylates IEA Mus musculus 456216 R-MMU-5218806 https://reactome.org/PathwayBrowser/#/R-MMU-5218806 FYN autophosphorylates IEA Mus musculus 456216 R-MMU-5218809 https://reactome.org/PathwayBrowser/#/R-MMU-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Mus musculus 456216 R-MMU-5218812 https://reactome.org/PathwayBrowser/#/R-MMU-5218812 FYN phosphorylates PAK2 IEA Mus musculus 456216 R-MMU-5218814 https://reactome.org/PathwayBrowser/#/R-MMU-5218814 PAK2 autophorylates IEA Mus musculus 456216 R-MMU-5218819 https://reactome.org/PathwayBrowser/#/R-MMU-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-5218820 https://reactome.org/PathwayBrowser/#/R-MMU-5218820 Src kinases phosphorylate VAV IEA Mus musculus 456216 R-MMU-5218821 https://reactome.org/PathwayBrowser/#/R-MMU-5218821 PDK1 phosphorylates PKC IEA Mus musculus 456216 R-MMU-5218823 https://reactome.org/PathwayBrowser/#/R-MMU-5218823 PKC phosphorylates sphingosine kinase 1 IEA Mus musculus 456216 R-MMU-5218826 https://reactome.org/PathwayBrowser/#/R-MMU-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Mus musculus 456216 R-MMU-5218830 https://reactome.org/PathwayBrowser/#/R-MMU-5218830 SRC-1 phosphorylates PTK2-beta IEA Mus musculus 456216 R-MMU-5218834 https://reactome.org/PathwayBrowser/#/R-MMU-5218834 Fak/Src phosphorylate p130Cas TAS Mus musculus 456216 R-MMU-5218845 https://reactome.org/PathwayBrowser/#/R-MMU-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Mus musculus 456216 R-MMU-5218851 https://reactome.org/PathwayBrowser/#/R-MMU-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Mus musculus 456216 R-MMU-5218854 https://reactome.org/PathwayBrowser/#/R-MMU-5218854 p-Y420-FYN is phosphorylated on S21 IEA Mus musculus 456216 R-MMU-5218906 https://reactome.org/PathwayBrowser/#/R-MMU-5218906 RIPK3 phosphorylates MLKL IEA Mus musculus 456216 R-MMU-5218916 https://reactome.org/PathwayBrowser/#/R-MMU-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Mus musculus 456216 R-MMU-5223313 https://reactome.org/PathwayBrowser/#/R-MMU-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Mus musculus 456216 R-MMU-5223317 https://reactome.org/PathwayBrowser/#/R-MMU-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Mus musculus 456216 R-MMU-5229194 https://reactome.org/PathwayBrowser/#/R-MMU-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Mus musculus 456216 R-MMU-5229343 https://reactome.org/PathwayBrowser/#/R-MMU-5229343 AXIN is phosphorylated in the destruction complex IEA Mus musculus 456216 R-MMU-5244669 https://reactome.org/PathwayBrowser/#/R-MMU-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Mus musculus 456216 R-MMU-5251955 https://reactome.org/PathwayBrowser/#/R-MMU-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Mus musculus 456216 R-MMU-5251959 https://reactome.org/PathwayBrowser/#/R-MMU-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Mus musculus 456216 R-MMU-5251989 https://reactome.org/PathwayBrowser/#/R-MMU-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Mus musculus 456216 R-MMU-5252079 https://reactome.org/PathwayBrowser/#/R-MMU-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Mus musculus 456216 R-MMU-5263624 https://reactome.org/PathwayBrowser/#/R-MMU-5263624 p-Akt2 phosphorylates C2cd5 TAS Mus musculus 456216 R-MMU-5357429 https://reactome.org/PathwayBrowser/#/R-MMU-5357429 AXL autophosphorylates on Y779 and Y821 IEA Mus musculus 456216 R-MMU-5357472 https://reactome.org/PathwayBrowser/#/R-MMU-5357472 PAK1-3 autophosphorylates IEA Mus musculus 456216 R-MMU-5357477 https://reactome.org/PathwayBrowser/#/R-MMU-5357477 PAK1-3 phosphorylates VE-cadherin IEA Mus musculus 456216 R-MMU-5357831 https://reactome.org/PathwayBrowser/#/R-MMU-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Mus musculus 456216 R-MMU-5358513 https://reactome.org/PathwayBrowser/#/R-MMU-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Mus musculus 456216 R-MMU-5358525 https://reactome.org/PathwayBrowser/#/R-MMU-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Mus musculus 456216 R-MMU-5358912 https://reactome.org/PathwayBrowser/#/R-MMU-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Mus musculus 456216 R-MMU-5362459 https://reactome.org/PathwayBrowser/#/R-MMU-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Mus musculus 456216 R-MMU-5444511 https://reactome.org/PathwayBrowser/#/R-MMU-5444511 Formation of MSH2:MSH3 Complex IEA Mus musculus 456216 R-MMU-5444516 https://reactome.org/PathwayBrowser/#/R-MMU-5444516 Formation of MSH2:MSH6 Complex IEA Mus musculus 456216 R-MMU-548973 https://reactome.org/PathwayBrowser/#/R-MMU-548973 Phosphorylation of ITIM in SIRP alpha TAS Mus musculus 456216 R-MMU-5578777 https://reactome.org/PathwayBrowser/#/R-MMU-5578777 DMPK phosphorylates PLN IEA Mus musculus 456216 R-MMU-5607722 https://reactome.org/PathwayBrowser/#/R-MMU-5607722 Active NIK phosphorylates IKKA dimer IEA Mus musculus 456216 R-MMU-5607726 https://reactome.org/PathwayBrowser/#/R-MMU-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Mus musculus 456216 R-MMU-5607732 https://reactome.org/PathwayBrowser/#/R-MMU-5607732 K63polyUb-TAK1 autophosphorylates IEA Mus musculus 456216 R-MMU-5607740 https://reactome.org/PathwayBrowser/#/R-MMU-5607740 PKC-delta phosphorylates CARD9 IEA Mus musculus 456216 R-MMU-5607742 https://reactome.org/PathwayBrowser/#/R-MMU-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Mus musculus 456216 R-MMU-5607750 https://reactome.org/PathwayBrowser/#/R-MMU-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Mus musculus 456216 R-MMU-5607754 https://reactome.org/PathwayBrowser/#/R-MMU-5607754 1,3-beta-D-glucan:p-15Y-Clec7a:Syk phosphorylates Plcg2 TAS Mus musculus 456216 R-MMU-5610710 https://reactome.org/PathwayBrowser/#/R-MMU-5610710 Pka phosphorylates Gli2 TAS Mus musculus 456216 R-MMU-5610720 https://reactome.org/PathwayBrowser/#/R-MMU-5610720 PKA phosphorylates GLI3 IEA Mus musculus 456216 R-MMU-5610722 https://reactome.org/PathwayBrowser/#/R-MMU-5610722 CK1 phosphorylates p-GLI3 IEA Mus musculus 456216 R-MMU-5610732 https://reactome.org/PathwayBrowser/#/R-MMU-5610732 GSK3 phosphorylates p-GLI3 IEA Mus musculus 456216 R-MMU-5617179 https://reactome.org/PathwayBrowser/#/R-MMU-5617179 PRKACA phosphorylates TNNI3 IEA Mus musculus 456216 R-MMU-5617182 https://reactome.org/PathwayBrowser/#/R-MMU-5617182 PRKACA phosphorylates PLN IEA Mus musculus 456216 R-MMU-5618085 https://reactome.org/PathwayBrowser/#/R-MMU-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Mus musculus 456216 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 456216 R-MMU-5618098 https://reactome.org/PathwayBrowser/#/R-MMU-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Mus musculus 456216 R-MMU-5618105 https://reactome.org/PathwayBrowser/#/R-MMU-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Mus musculus 456216 R-MMU-5618107 https://reactome.org/PathwayBrowser/#/R-MMU-5618107 ATP binding to HSP90 triggers conformation change IEA Mus musculus 456216 R-MMU-5618110 https://reactome.org/PathwayBrowser/#/R-MMU-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Mus musculus 456216 R-MMU-5621355 https://reactome.org/PathwayBrowser/#/R-MMU-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Mus musculus 456216 R-MMU-5621363 https://reactome.org/PathwayBrowser/#/R-MMU-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Mus musculus 456216 R-MMU-5621370 https://reactome.org/PathwayBrowser/#/R-MMU-5621370 SYK autophosphorylates IEA Mus musculus 456216 R-MMU-5623667 https://reactome.org/PathwayBrowser/#/R-MMU-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Mus musculus 456216 R-MMU-5624473 https://reactome.org/PathwayBrowser/#/R-MMU-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Mus musculus 456216 R-MMU-5624486 https://reactome.org/PathwayBrowser/#/R-MMU-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Mus musculus 456216 R-MMU-5624492 https://reactome.org/PathwayBrowser/#/R-MMU-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Mus musculus 456216 R-MMU-5627775 https://reactome.org/PathwayBrowser/#/R-MMU-5627775 Autophosphorylation of PAK1,2,3 IEA Mus musculus 456216 R-MMU-5632661 https://reactome.org/PathwayBrowser/#/R-MMU-5632661 Csnk1a1 phosphorylates Smo dimer TAS Mus musculus 456216 R-MMU-5632665 https://reactome.org/PathwayBrowser/#/R-MMU-5632665 Adrbk1 phosphorylates Smo dimer TAS Mus musculus 456216 R-MMU-5635842 https://reactome.org/PathwayBrowser/#/R-MMU-5635842 ULK3 phosphorylates GLI IEA Mus musculus 456216 R-MMU-5654147 https://reactome.org/PathwayBrowser/#/R-MMU-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Mus musculus 456216 R-MMU-5654149 https://reactome.org/PathwayBrowser/#/R-MMU-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Mus musculus 456216 R-MMU-5654151 https://reactome.org/PathwayBrowser/#/R-MMU-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Mus musculus 456216 R-MMU-5654222 https://reactome.org/PathwayBrowser/#/R-MMU-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Mus musculus 456216 R-MMU-5654397 https://reactome.org/PathwayBrowser/#/R-MMU-5654397 Activated FGFR2 phosphorylates FRS2 IEA Mus musculus 456216 R-MMU-5654407 https://reactome.org/PathwayBrowser/#/R-MMU-5654407 Activated FGFR2 phosphorylates SHC1 IEA Mus musculus 456216 R-MMU-5654408 https://reactome.org/PathwayBrowser/#/R-MMU-5654408 Activated FGFR3 phosphorylates FRS2 IEA Mus musculus 456216 R-MMU-5654418 https://reactome.org/PathwayBrowser/#/R-MMU-5654418 Activated FGFR4 phosphorylates FRS2 IEA Mus musculus 456216 R-MMU-5654428 https://reactome.org/PathwayBrowser/#/R-MMU-5654428 Activated FGFR4 phosphorylates SHC1 IEA Mus musculus 456216 R-MMU-5654560 https://reactome.org/PathwayBrowser/#/R-MMU-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Mus musculus 456216 R-MMU-5654562 https://reactome.org/PathwayBrowser/#/R-MMU-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Mus musculus 456216 R-MMU-5654565 https://reactome.org/PathwayBrowser/#/R-MMU-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Mus musculus 456216 R-MMU-5654566 https://reactome.org/PathwayBrowser/#/R-MMU-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Mus musculus 456216 R-MMU-5654575 https://reactome.org/PathwayBrowser/#/R-MMU-5654575 Activated FGFR1 phosphorylates FRS2 IEA Mus musculus 456216 R-MMU-5654578 https://reactome.org/PathwayBrowser/#/R-MMU-5654578 Activated FGFR1 phosphorylates FRS3 IEA Mus musculus 456216 R-MMU-5654582 https://reactome.org/PathwayBrowser/#/R-MMU-5654582 Activated FGFR1 phosphorylates SHC1 IEA Mus musculus 456216 R-MMU-5654587 https://reactome.org/PathwayBrowser/#/R-MMU-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Mus musculus 456216 R-MMU-5654605 https://reactome.org/PathwayBrowser/#/R-MMU-5654605 Activated FGFR2 phosphorylates FRS3 IEA Mus musculus 456216 R-MMU-5654607 https://reactome.org/PathwayBrowser/#/R-MMU-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Mus musculus 456216 R-MMU-5654628 https://reactome.org/PathwayBrowser/#/R-MMU-5654628 Activated FGFR3 phosphorylates FRS3 IEA Mus musculus 456216 R-MMU-5654631 https://reactome.org/PathwayBrowser/#/R-MMU-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Mus musculus 456216 R-MMU-5654634 https://reactome.org/PathwayBrowser/#/R-MMU-5654634 Activated FGFR3 phosphorylates SHC1 IEA Mus musculus 456216 R-MMU-5654653 https://reactome.org/PathwayBrowser/#/R-MMU-5654653 Activated FGFR4 phosphorylates FRS3 IEA Mus musculus 456216 R-MMU-5654655 https://reactome.org/PathwayBrowser/#/R-MMU-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Mus musculus 456216 R-MMU-5654690 https://reactome.org/PathwayBrowser/#/R-MMU-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-5654692 https://reactome.org/PathwayBrowser/#/R-MMU-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-5654697 https://reactome.org/PathwayBrowser/#/R-MMU-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-5654701 https://reactome.org/PathwayBrowser/#/R-MMU-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-5654705 https://reactome.org/PathwayBrowser/#/R-MMU-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-5654709 https://reactome.org/PathwayBrowser/#/R-MMU-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-5654714 https://reactome.org/PathwayBrowser/#/R-MMU-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-5654717 https://reactome.org/PathwayBrowser/#/R-MMU-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-5654989 https://reactome.org/PathwayBrowser/#/R-MMU-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Mus musculus 456216 R-MMU-5662466 https://reactome.org/PathwayBrowser/#/R-MMU-5662466 XYLB phosphorylates D-xylulose IEA Mus musculus 456216 R-MMU-5665868 https://reactome.org/PathwayBrowser/#/R-MMU-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Mus musculus 456216 R-MMU-5666160 https://reactome.org/PathwayBrowser/#/R-MMU-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Mus musculus 456216 R-MMU-5668545 https://reactome.org/PathwayBrowser/#/R-MMU-5668545 NIK autophosphorylates on T559 IEA Mus musculus 456216 R-MMU-5668932 https://reactome.org/PathwayBrowser/#/R-MMU-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Mus musculus 456216 R-MMU-5668947 https://reactome.org/PathwayBrowser/#/R-MMU-5668947 PAK1 phosphorylates myosin phosphatase IEA Mus musculus 456216 R-MMU-5668984 https://reactome.org/PathwayBrowser/#/R-MMU-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Mus musculus 456216 R-MMU-5669250 https://reactome.org/PathwayBrowser/#/R-MMU-5669250 PAK1 phosphorylates FLNA IEA Mus musculus 456216 R-MMU-5671749 https://reactome.org/PathwayBrowser/#/R-MMU-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Mus musculus 456216 R-MMU-5671763 https://reactome.org/PathwayBrowser/#/R-MMU-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Mus musculus 456216 R-MMU-5672008 https://reactome.org/PathwayBrowser/#/R-MMU-5672008 Thr-180 of ULK1 is phosphorylated IEA Mus musculus 456216 R-MMU-5672010 https://reactome.org/PathwayBrowser/#/R-MMU-5672010 Active MTORC1 phosphorylates ULK1 IEA Mus musculus 456216 R-MMU-5672012 https://reactome.org/PathwayBrowser/#/R-MMU-5672012 Beclin-1 complex phosphorylates PtdIns IEA Mus musculus 456216 R-MMU-5672027 https://reactome.org/PathwayBrowser/#/R-MMU-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Mus musculus 456216 R-MMU-5672828 https://reactome.org/PathwayBrowser/#/R-MMU-5672828 mTORC1 phosphorylates AKT1S1 IEA Mus musculus 456216 R-MMU-5672948 https://reactome.org/PathwayBrowser/#/R-MMU-5672948 MARK3 phosphorylates KSR1 IEA Mus musculus 456216 R-MMU-5672969 https://reactome.org/PathwayBrowser/#/R-MMU-5672969 Phosphorylation of RAF IEA Mus musculus 456216 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 456216 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 456216 R-MMU-5673768 https://reactome.org/PathwayBrowser/#/R-MMU-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Mus musculus 456216 R-MMU-5674130 https://reactome.org/PathwayBrowser/#/R-MMU-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Mus musculus 456216 R-MMU-5674373 https://reactome.org/PathwayBrowser/#/R-MMU-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Mus musculus 456216 R-MMU-5674496 https://reactome.org/PathwayBrowser/#/R-MMU-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Mus musculus 456216 R-MMU-5675194 https://reactome.org/PathwayBrowser/#/R-MMU-5675194 Activated MAPK phosphorylates RAF1 IEA Mus musculus 456216 R-MMU-5675198 https://reactome.org/PathwayBrowser/#/R-MMU-5675198 Activated MAPKs phosphorylate BRAF IEA Mus musculus 456216 R-MMU-5675868 https://reactome.org/PathwayBrowser/#/R-MMU-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Mus musculus 456216 R-MMU-5678706 https://reactome.org/PathwayBrowser/#/R-MMU-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Mus musculus 456216 R-MMU-5678863 https://reactome.org/PathwayBrowser/#/R-MMU-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-5679041 https://reactome.org/PathwayBrowser/#/R-MMU-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-5679205 https://reactome.org/PathwayBrowser/#/R-MMU-5679205 ULK1 phosphorylates Beclin-1 IEA Mus musculus 456216 R-MMU-5682026 https://reactome.org/PathwayBrowser/#/R-MMU-5682026 MRN bound to shortened telomeres activates ATM IEA Mus musculus 456216 R-MMU-5682101 https://reactome.org/PathwayBrowser/#/R-MMU-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Mus musculus 456216 R-MMU-5682285 https://reactome.org/PathwayBrowser/#/R-MMU-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-5682598 https://reactome.org/PathwayBrowser/#/R-MMU-5682598 ATM phosphorylates HERC2 IEA Mus musculus 456216 R-MMU-5682983 https://reactome.org/PathwayBrowser/#/R-MMU-5682983 ATM phosphorylates WHSC1 IEA Mus musculus 456216 R-MMU-5683425 https://reactome.org/PathwayBrowser/#/R-MMU-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Mus musculus 456216 R-MMU-5683714 https://reactome.org/PathwayBrowser/#/R-MMU-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Mus musculus 456216 R-MMU-5683792 https://reactome.org/PathwayBrowser/#/R-MMU-5683792 p-T68-CHEK2 autophosphorylates IEA Mus musculus 456216 R-MMU-5683801 https://reactome.org/PathwayBrowser/#/R-MMU-5683801 CHEK2 phosphorylates BRCA1 IEA Mus musculus 456216 R-MMU-5683930 https://reactome.org/PathwayBrowser/#/R-MMU-5683930 WICH phosphorylates H2AFX on Y142 IEA Mus musculus 456216 R-MMU-5683964 https://reactome.org/PathwayBrowser/#/R-MMU-5683964 ATM phosphorylates EYA1-4 IEA Mus musculus 456216 R-MMU-5684096 https://reactome.org/PathwayBrowser/#/R-MMU-5684096 CDK2 phosphorylates RBBP8 IEA Mus musculus 456216 R-MMU-5684140 https://reactome.org/PathwayBrowser/#/R-MMU-5684140 ATM phosphorylates RBBP8 IEA Mus musculus 456216 R-MMU-5684261 https://reactome.org/PathwayBrowser/#/R-MMU-5684261 MAP3K8 is phosphorylated IEA Mus musculus 456216 R-MMU-5684267 https://reactome.org/PathwayBrowser/#/R-MMU-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex IEA Mus musculus 456216 R-MMU-5684275 https://reactome.org/PathwayBrowser/#/R-MMU-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 IEA Mus musculus 456216 R-MMU-5684806 https://reactome.org/PathwayBrowser/#/R-MMU-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN IEA Mus musculus 456216 R-MMU-5684887 https://reactome.org/PathwayBrowser/#/R-MMU-5684887 Activation of CHEK1 at resected DNA DSBs IEA Mus musculus 456216 R-MMU-5685156 https://reactome.org/PathwayBrowser/#/R-MMU-5685156 ATR phosphorylates RPA2 IEA Mus musculus 456216 R-MMU-5685230 https://reactome.org/PathwayBrowser/#/R-MMU-5685230 CHEK1 phosphorylates RAD51 IEA Mus musculus 456216 R-MMU-5686578 https://reactome.org/PathwayBrowser/#/R-MMU-5686578 Activated ATM phosphorylates ABL1 IEA Mus musculus 456216 R-MMU-5686587 https://reactome.org/PathwayBrowser/#/R-MMU-5686587 ABL1 phosphorylates RAD52 IEA Mus musculus 456216 R-MMU-5686704 https://reactome.org/PathwayBrowser/#/R-MMU-5686704 Activated ATM phosphorylates DCLRE1C IEA Mus musculus 456216 R-MMU-5687086 https://reactome.org/PathwayBrowser/#/R-MMU-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Mus musculus 456216 R-MMU-5687088 https://reactome.org/PathwayBrowser/#/R-MMU-5687088 PKA phosphorylates MAPKAPK5 IEA Mus musculus 456216 R-MMU-5687090 https://reactome.org/PathwayBrowser/#/R-MMU-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Mus musculus 456216 R-MMU-5687094 https://reactome.org/PathwayBrowser/#/R-MMU-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Mus musculus 456216 R-MMU-5687101 https://reactome.org/PathwayBrowser/#/R-MMU-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Mus musculus 456216 R-MMU-5687121 https://reactome.org/PathwayBrowser/#/R-MMU-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Mus musculus 456216 R-MMU-5687183 https://reactome.org/PathwayBrowser/#/R-MMU-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Mus musculus 456216 R-MMU-5690250 https://reactome.org/PathwayBrowser/#/R-MMU-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Mus musculus 456216 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus 456216 R-MMU-5690996 https://reactome.org/PathwayBrowser/#/R-MMU-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Mus musculus 456216 R-MMU-5692462 https://reactome.org/PathwayBrowser/#/R-MMU-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Mus musculus 456216 R-MMU-5692480 https://reactome.org/PathwayBrowser/#/R-MMU-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Mus musculus 456216 R-MMU-5692755 https://reactome.org/PathwayBrowser/#/R-MMU-5692755 CDK1 phosphorylates MAPK6 IEA Mus musculus 456216 R-MMU-5692768 https://reactome.org/PathwayBrowser/#/R-MMU-5692768 MAPKAPK5 phosphorylates KALRN IEA Mus musculus 456216 R-MMU-5692775 https://reactome.org/PathwayBrowser/#/R-MMU-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Mus musculus 456216 R-MMU-5692779 https://reactome.org/PathwayBrowser/#/R-MMU-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Mus musculus 456216 R-MMU-5693148 https://reactome.org/PathwayBrowser/#/R-MMU-5693148 BCKDK phosphorylates BCKDH IEA Mus musculus 456216 R-MMU-5693536 https://reactome.org/PathwayBrowser/#/R-MMU-5693536 ATM phosphorylates MDC1 IEA Mus musculus 456216 R-MMU-5693540 https://reactome.org/PathwayBrowser/#/R-MMU-5693540 MRN activates ATM IEA Mus musculus 456216 R-MMU-5693549 https://reactome.org/PathwayBrowser/#/R-MMU-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Mus musculus 456216 R-MMU-5693551 https://reactome.org/PathwayBrowser/#/R-MMU-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Mus musculus 456216 R-MMU-5693575 https://reactome.org/PathwayBrowser/#/R-MMU-5693575 DNA-PKcs autophosphorylates IEA Mus musculus 456216 R-MMU-5693598 https://reactome.org/PathwayBrowser/#/R-MMU-5693598 ATM phosphorylates NBN IEA Mus musculus 456216 R-MMU-5693609 https://reactome.org/PathwayBrowser/#/R-MMU-5693609 ATM phosphorylates TP53 at S15 IEA Mus musculus 456216 R-MMU-5694441 https://reactome.org/PathwayBrowser/#/R-MMU-5694441 CSNK1D phosphorylates SEC23 IEA Mus musculus 456216 R-MMU-5696021 https://reactome.org/PathwayBrowser/#/R-MMU-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Mus musculus 456216 R-MMU-5696074 https://reactome.org/PathwayBrowser/#/R-MMU-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Mus musculus 456216 R-MMU-5696839 https://reactome.org/PathwayBrowser/#/R-MMU-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Mus musculus 456216 R-MMU-6782131 https://reactome.org/PathwayBrowser/#/R-MMU-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Mus musculus 456216 R-MMU-6784006 https://reactome.org/PathwayBrowser/#/R-MMU-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Mus musculus 456216 R-MMU-6784319 https://reactome.org/PathwayBrowser/#/R-MMU-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Mus musculus 456216 R-MMU-6784324 https://reactome.org/PathwayBrowser/#/R-MMU-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Mus musculus 456216 R-MMU-6786050 https://reactome.org/PathwayBrowser/#/R-MMU-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Mus musculus 456216 R-MMU-6786095 https://reactome.org/PathwayBrowser/#/R-MMU-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Mus musculus 456216 R-MMU-6786096 https://reactome.org/PathwayBrowser/#/R-MMU-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Mus musculus 456216 R-MMU-6786245 https://reactome.org/PathwayBrowser/#/R-MMU-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Mus musculus 456216 R-MMU-6787540 https://reactome.org/PathwayBrowser/#/R-MMU-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Mus musculus 456216 R-MMU-6788392 https://reactome.org/PathwayBrowser/#/R-MMU-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Mus musculus 456216 R-MMU-6788582 https://reactome.org/PathwayBrowser/#/R-MMU-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Mus musculus 456216 R-MMU-6788798 https://reactome.org/PathwayBrowser/#/R-MMU-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 456216 R-MMU-6788810 https://reactome.org/PathwayBrowser/#/R-MMU-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 456216 R-MMU-6788855 https://reactome.org/PathwayBrowser/#/R-MMU-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Mus musculus 456216 R-MMU-6788867 https://reactome.org/PathwayBrowser/#/R-MMU-6788867 FN3K phosphorylates ketosamines IEA Mus musculus 456216 R-MMU-6790089 https://reactome.org/PathwayBrowser/#/R-MMU-6790089 Hvem induses Btla phosphorylation TAS Mus musculus 456216 R-MMU-6793661 https://reactome.org/PathwayBrowser/#/R-MMU-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Mus musculus 456216 R-MMU-6795290 https://reactome.org/PathwayBrowser/#/R-MMU-6795290 TORC2 complex phosphorylates SGK1 IEA Mus musculus 456216 R-MMU-6795460 https://reactome.org/PathwayBrowser/#/R-MMU-6795460 SGK1 phosphorylates MDM2 IEA Mus musculus 456216 R-MMU-6795473 https://reactome.org/PathwayBrowser/#/R-MMU-6795473 PDPK1 phosphorylates SGK1 IEA Mus musculus 456216 R-MMU-6797606 https://reactome.org/PathwayBrowser/#/R-MMU-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Mus musculus 456216 R-MMU-6798174 https://reactome.org/PathwayBrowser/#/R-MMU-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Mus musculus 456216 R-MMU-6798372 https://reactome.org/PathwayBrowser/#/R-MMU-6798372 ATM phosphorylates DYRK2 IEA Mus musculus 456216 R-MMU-6798374 https://reactome.org/PathwayBrowser/#/R-MMU-6798374 DYRK2 phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6799097 https://reactome.org/PathwayBrowser/#/R-MMU-6799097 ATM phosphorylates ZNF420 IEA Mus musculus 456216 R-MMU-6799246 https://reactome.org/PathwayBrowser/#/R-MMU-6799246 CHEK1 phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6799332 https://reactome.org/PathwayBrowser/#/R-MMU-6799332 ATR phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6799409 https://reactome.org/PathwayBrowser/#/R-MMU-6799409 HIPK2 phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6799495 https://reactome.org/PathwayBrowser/#/R-MMU-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Mus musculus 456216 R-MMU-6800490 https://reactome.org/PathwayBrowser/#/R-MMU-6800490 ATM phosphorylates PIDD1 IEA Mus musculus 456216 R-MMU-6801342 https://reactome.org/PathwayBrowser/#/R-MMU-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Mus musculus 456216 R-MMU-6801456 https://reactome.org/PathwayBrowser/#/R-MMU-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Mus musculus 456216 R-MMU-6801666 https://reactome.org/PathwayBrowser/#/R-MMU-6801666 PLK2 phosphorylates CENPJ IEA Mus musculus 456216 R-MMU-6801675 https://reactome.org/PathwayBrowser/#/R-MMU-6801675 PLK2 phosphorylates NPM1 IEA Mus musculus 456216 R-MMU-6802973 https://reactome.org/PathwayBrowser/#/R-MMU-6802973 PLK3 phosphorylates CDC25C IEA Mus musculus 456216 R-MMU-6803545 https://reactome.org/PathwayBrowser/#/R-MMU-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Mus musculus 456216 R-MMU-6803771 https://reactome.org/PathwayBrowser/#/R-MMU-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Mus musculus 456216 R-MMU-6804266 https://reactome.org/PathwayBrowser/#/R-MMU-6804266 CHEK2 phosphorylates TTC5 IEA Mus musculus 456216 R-MMU-6804276 https://reactome.org/PathwayBrowser/#/R-MMU-6804276 ATM phosphorylates TTC5 IEA Mus musculus 456216 R-MMU-6804955 https://reactome.org/PathwayBrowser/#/R-MMU-6804955 ATM phosphorylates MDM2 IEA Mus musculus 456216 R-MMU-6805059 https://reactome.org/PathwayBrowser/#/R-MMU-6805059 CK2:FACT phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6805103 https://reactome.org/PathwayBrowser/#/R-MMU-6805103 AURKA phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6805109 https://reactome.org/PathwayBrowser/#/R-MMU-6805109 CDK2 phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6805126 https://reactome.org/PathwayBrowser/#/R-MMU-6805126 AURKB phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6805276 https://reactome.org/PathwayBrowser/#/R-MMU-6805276 CDK5 phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6805285 https://reactome.org/PathwayBrowser/#/R-MMU-6805285 PLK3 phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6805399 https://reactome.org/PathwayBrowser/#/R-MMU-6805399 TAF1 phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6805470 https://reactome.org/PathwayBrowser/#/R-MMU-6805470 AMPK phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6805479 https://reactome.org/PathwayBrowser/#/R-MMU-6805479 TP53RK phosphorylates TP53 IEA Mus musculus 456216 R-MMU-6805507 https://reactome.org/PathwayBrowser/#/R-MMU-6805507 APAF1 binds AVEN IEA Mus musculus 456216 R-MMU-6805640 https://reactome.org/PathwayBrowser/#/R-MMU-6805640 AKT phosphorylates KAT6A IEA Mus musculus 456216 R-MMU-6805785 https://reactome.org/PathwayBrowser/#/R-MMU-6805785 AKT phosphorylates PHF20 IEA Mus musculus 456216 R-MMU-6806877 https://reactome.org/PathwayBrowser/#/R-MMU-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Mus musculus 456216 R-MMU-6806967 https://reactome.org/PathwayBrowser/#/R-MMU-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Mus musculus 456216 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 456216 R-MMU-6807868 https://reactome.org/PathwayBrowser/#/R-MMU-6807868 GBF1 stimulates ARF nucleotide exchange IEA Mus musculus 456216 R-MMU-6810233 https://reactome.org/PathwayBrowser/#/R-MMU-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Mus musculus 456216 R-MMU-6810472 https://reactome.org/PathwayBrowser/#/R-MMU-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Mus musculus 456216 R-MMU-6811454 https://reactome.org/PathwayBrowser/#/R-MMU-6811454 MAPKs phosphorylate PP2A IEA Mus musculus 456216 R-MMU-6811522 https://reactome.org/PathwayBrowser/#/R-MMU-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Mus musculus 456216 R-MMU-6814119 https://reactome.org/PathwayBrowser/#/R-MMU-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Mus musculus 456216 R-MMU-6814120 https://reactome.org/PathwayBrowser/#/R-MMU-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Mus musculus 456216 R-MMU-6814121 https://reactome.org/PathwayBrowser/#/R-MMU-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Mus musculus 456216 R-MMU-6814124 https://reactome.org/PathwayBrowser/#/R-MMU-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Mus musculus 456216 R-MMU-6814409 https://reactome.org/PathwayBrowser/#/R-MMU-6814409 CK2 phosphorylates PDCL IEA Mus musculus 456216 R-MMU-6814670 https://reactome.org/PathwayBrowser/#/R-MMU-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Mus musculus 456216 R-MMU-6814683 https://reactome.org/PathwayBrowser/#/R-MMU-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Mus musculus 456216 R-MMU-68944 https://reactome.org/PathwayBrowser/#/R-MMU-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Mus musculus 456216 R-MMU-68954 https://reactome.org/PathwayBrowser/#/R-MMU-68954 Mcm2-7 is phosphorylated by DDK IEA Mus musculus 456216 R-MMU-69005 https://reactome.org/PathwayBrowser/#/R-MMU-69005 Cdc6 protein is phosphorylated by CDK IEA Mus musculus 456216 R-MMU-69063 https://reactome.org/PathwayBrowser/#/R-MMU-69063 Loading of PCNA - Sliding Clamp Formation IEA Mus musculus 456216 R-MMU-69195 https://reactome.org/PathwayBrowser/#/R-MMU-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Mus musculus 456216 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 456216 R-MMU-69604 https://reactome.org/PathwayBrowser/#/R-MMU-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Mus musculus 456216 R-MMU-69608 https://reactome.org/PathwayBrowser/#/R-MMU-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Mus musculus 456216 R-MMU-69685 https://reactome.org/PathwayBrowser/#/R-MMU-69685 CHEK2 phosphorylates TP53 IEA Mus musculus 456216 R-MMU-69891 https://reactome.org/PathwayBrowser/#/R-MMU-69891 Phosphorylation and activation of CHEK2 by ATM IEA Mus musculus 456216 R-MMU-70333 https://reactome.org/PathwayBrowser/#/R-MMU-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Mus musculus 456216 R-MMU-70349 https://reactome.org/PathwayBrowser/#/R-MMU-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Mus musculus 456216 R-MMU-70355 https://reactome.org/PathwayBrowser/#/R-MMU-70355 GALK1 phosphorylates Gal to Gal1P IEA Mus musculus 456216 R-MMU-70420 https://reactome.org/PathwayBrowser/#/R-MMU-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Mus musculus 456216 R-MMU-70467 https://reactome.org/PathwayBrowser/#/R-MMU-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Mus musculus 456216 R-MMU-70486 https://reactome.org/PathwayBrowser/#/R-MMU-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Mus musculus 456216 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 456216 R-MMU-70555 https://reactome.org/PathwayBrowser/#/R-MMU-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Mus musculus 456216 R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Mus musculus 456216 R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Mus musculus 456216 R-MMU-70606 https://reactome.org/PathwayBrowser/#/R-MMU-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Mus musculus 456216 R-MMU-70773 https://reactome.org/PathwayBrowser/#/R-MMU-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Mus musculus 456216 R-MMU-70967 https://reactome.org/PathwayBrowser/#/R-MMU-70967 IDH3 complex decarboxylates isocitrate IEA Mus musculus 456216 R-MMU-70997 https://reactome.org/PathwayBrowser/#/R-MMU-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Mus musculus 456216 R-MMU-71031 https://reactome.org/PathwayBrowser/#/R-MMU-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Mus musculus 456216 R-MMU-71401 https://reactome.org/PathwayBrowser/#/R-MMU-71401 OGDH dimer decarboxylates 2-OG IEA Mus musculus 456216 R-MMU-71541 https://reactome.org/PathwayBrowser/#/R-MMU-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Mus musculus 456216 R-MMU-71588 https://reactome.org/PathwayBrowser/#/R-MMU-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Mus musculus 456216 R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 456216 R-MMU-71802 https://reactome.org/PathwayBrowser/#/R-MMU-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Mus musculus 456216 R-MMU-71850 https://reactome.org/PathwayBrowser/#/R-MMU-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Mus musculus 456216 R-MMU-72621 https://reactome.org/PathwayBrowser/#/R-MMU-72621 Ribosomal scanning IEA Mus musculus 456216 R-MMU-72647 https://reactome.org/PathwayBrowser/#/R-MMU-72647 Cap-bound mRNA is activated by helicases IEA Mus musculus 456216 R-MMU-727819 https://reactome.org/PathwayBrowser/#/R-MMU-727819 TAK1 phosphorylates MKK6 IEA Mus musculus 456216 R-MMU-73548 https://reactome.org/PathwayBrowser/#/R-MMU-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Mus musculus 456216 R-MMU-73577 https://reactome.org/PathwayBrowser/#/R-MMU-73577 CAD hexamer transforms L-Gln to CAP IEA Mus musculus 456216 R-MMU-73598 https://reactome.org/PathwayBrowser/#/R-MMU-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Mus musculus 456216 R-MMU-73599 https://reactome.org/PathwayBrowser/#/R-MMU-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Mus musculus 456216 R-MMU-73632 https://reactome.org/PathwayBrowser/#/R-MMU-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Mus musculus 456216 R-MMU-73635 https://reactome.org/PathwayBrowser/#/R-MMU-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Mus musculus 456216 R-MMU-73647 https://reactome.org/PathwayBrowser/#/R-MMU-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Mus musculus 456216 R-MMU-73722 https://reactome.org/PathwayBrowser/#/R-MMU-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Mus musculus 456216 R-MMU-73788 https://reactome.org/PathwayBrowser/#/R-MMU-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Mus musculus 456216 R-MMU-73805 https://reactome.org/PathwayBrowser/#/R-MMU-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Mus musculus 456216 R-MMU-73810 https://reactome.org/PathwayBrowser/#/R-MMU-73810 FGAM + ATP => AIR + ADP + Pi IEA Mus musculus 456216 R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 456216 R-MMU-73814 https://reactome.org/PathwayBrowser/#/R-MMU-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Mus musculus 456216 R-MMU-74207 https://reactome.org/PathwayBrowser/#/R-MMU-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Mus musculus 456216 R-MMU-74220 https://reactome.org/PathwayBrowser/#/R-MMU-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Mus musculus 456216 R-MMU-74711 https://reactome.org/PathwayBrowser/#/R-MMU-74711 Phosphorylation of IRS IEA Mus musculus 456216 R-MMU-74715 https://reactome.org/PathwayBrowser/#/R-MMU-74715 Autophosphorylation of insulin receptor IEA Mus musculus 456216 R-MMU-74742 https://reactome.org/PathwayBrowser/#/R-MMU-74742 Phosphorylation of SHC1 IEA Mus musculus 456216 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 456216 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 456216 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 456216 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 456216 R-MMU-75010 https://reactome.org/PathwayBrowser/#/R-MMU-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Mus musculus 456216 R-MMU-75125 https://reactome.org/PathwayBrowser/#/R-MMU-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Mus musculus 456216 R-MMU-75126 https://reactome.org/PathwayBrowser/#/R-MMU-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Mus musculus 456216 R-MMU-75809 https://reactome.org/PathwayBrowser/#/R-MMU-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Mus musculus 456216 R-MMU-75848 https://reactome.org/PathwayBrowser/#/R-MMU-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Mus musculus 456216 R-MMU-75851 https://reactome.org/PathwayBrowser/#/R-MMU-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 456216 R-MMU-75887 https://reactome.org/PathwayBrowser/#/R-MMU-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Mus musculus 456216 R-MMU-75949 https://reactome.org/PathwayBrowser/#/R-MMU-75949 RNA Polymerase II Promoter Opening: First Transition IEA Mus musculus 456216 R-MMU-77071 https://reactome.org/PathwayBrowser/#/R-MMU-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Mus musculus 456216 R-MMU-873918 https://reactome.org/PathwayBrowser/#/R-MMU-873918 Transphosphorylation of JAK1 IEA Mus musculus 456216 R-MMU-873919 https://reactome.org/PathwayBrowser/#/R-MMU-873919 Phosphorylation of JAK2 IEA Mus musculus 456216 R-MMU-873922 https://reactome.org/PathwayBrowser/#/R-MMU-873922 Phosphorylation of STAT1 by JAK kinases IEA Mus musculus 456216 R-MMU-873924 https://reactome.org/PathwayBrowser/#/R-MMU-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Mus musculus 456216 R-MMU-879907 https://reactome.org/PathwayBrowser/#/R-MMU-879907 Tyrosine kinases phosphorylate the receptor IEA Mus musculus 456216 R-MMU-879909 https://reactome.org/PathwayBrowser/#/R-MMU-879909 Activation of STAT5a/b by JAK2 IEA Mus musculus 456216 R-MMU-879910 https://reactome.org/PathwayBrowser/#/R-MMU-879910 JAK2 is phosphorylated, activated IEA Mus musculus 456216 R-MMU-8847638 https://reactome.org/PathwayBrowser/#/R-MMU-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Mus musculus 456216 R-MMU-8847977 https://reactome.org/PathwayBrowser/#/R-MMU-8847977 FRK phosphorylates PTEN IEA Mus musculus 456216 R-MMU-8848005 https://reactome.org/PathwayBrowser/#/R-MMU-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Mus musculus 456216 R-MMU-8848053 https://reactome.org/PathwayBrowser/#/R-MMU-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Mus musculus 456216 R-MMU-8848077 https://reactome.org/PathwayBrowser/#/R-MMU-8848077 PTK6 phosphorylates STAP2 IEA Mus musculus 456216 R-MMU-8848124 https://reactome.org/PathwayBrowser/#/R-MMU-8848124 PTK6 phosphorylates STAT3 IEA Mus musculus 456216 R-MMU-8848436 https://reactome.org/PathwayBrowser/#/R-MMU-8848436 PTK6 phosphorylates CDKN1B IEA Mus musculus 456216 R-MMU-8848606 https://reactome.org/PathwayBrowser/#/R-MMU-8848606 PTK6 phosphorylates PXN IEA Mus musculus 456216 R-MMU-8848726 https://reactome.org/PathwayBrowser/#/R-MMU-8848726 PTK6 phosphorylates BCAR1 IEA Mus musculus 456216 R-MMU-8848758 https://reactome.org/PathwayBrowser/#/R-MMU-8848758 PTK6 phosphorylates AKT1 IEA Mus musculus 456216 R-MMU-8848776 https://reactome.org/PathwayBrowser/#/R-MMU-8848776 PTK6 phosphorylates DOK1 IEA Mus musculus 456216 R-MMU-8848818 https://reactome.org/PathwayBrowser/#/R-MMU-8848818 PTK6 phosphorylates CBL IEA Mus musculus 456216 R-MMU-8848873 https://reactome.org/PathwayBrowser/#/R-MMU-8848873 PTK6 phosphorylates ARAP1 IEA Mus musculus 456216 R-MMU-8848975 https://reactome.org/PathwayBrowser/#/R-MMU-8848975 PTK6 phosphorylates KHDRBS1 IEA Mus musculus 456216 R-MMU-8849032 https://reactome.org/PathwayBrowser/#/R-MMU-8849032 PTK6 phosphorylates KHDRBS2 IEA Mus musculus 456216 R-MMU-8849042 https://reactome.org/PathwayBrowser/#/R-MMU-8849042 PTK6 phosphorylates KHDRBS3 IEA Mus musculus 456216 R-MMU-8849068 https://reactome.org/PathwayBrowser/#/R-MMU-8849068 PTK6 phosphorylates ARHGAP35 IEA Mus musculus 456216 R-MMU-8849102 https://reactome.org/PathwayBrowser/#/R-MMU-8849102 SRMS phosphorylates PTK6 IEA Mus musculus 456216 R-MMU-8849353 https://reactome.org/PathwayBrowser/#/R-MMU-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Mus musculus 456216 R-MMU-8849463 https://reactome.org/PathwayBrowser/#/R-MMU-8849463 PTK6 phosphorylates SFPQ IEA Mus musculus 456216 R-MMU-8850527 https://reactome.org/PathwayBrowser/#/R-MMU-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Mus musculus 456216 R-MMU-8850529 https://reactome.org/PathwayBrowser/#/R-MMU-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Mus musculus 456216 R-MMU-8850534 https://reactome.org/PathwayBrowser/#/R-MMU-8850534 PDCL promotes G-protein beta 5 folding IEA Mus musculus 456216 R-MMU-8850539 https://reactome.org/PathwayBrowser/#/R-MMU-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Mus musculus 456216 R-MMU-8850945 https://reactome.org/PathwayBrowser/#/R-MMU-8850945 Casein kinase II phosphorylates PTEN IEA Mus musculus 456216 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 456216 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 456216 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 456216 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 456216 R-MMU-8851797 https://reactome.org/PathwayBrowser/#/R-MMU-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Mus musculus 456216 R-MMU-8851890 https://reactome.org/PathwayBrowser/#/R-MMU-8851890 MET phosphorylates SHC1-2 IEA Mus musculus 456216 R-MMU-8851933 https://reactome.org/PathwayBrowser/#/R-MMU-8851933 MET phosphorylates GAB1 IEA Mus musculus 456216 R-MMU-8852019 https://reactome.org/PathwayBrowser/#/R-MMU-8852019 MET bound PI3K generates PIP3 IEA Mus musculus 456216 R-MMU-8852306 https://reactome.org/PathwayBrowser/#/R-MMU-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Mus musculus 456216 R-MMU-8852317 https://reactome.org/PathwayBrowser/#/R-MMU-8852317 PLK1 phosphorylates GTSE1 IEA Mus musculus 456216 R-MMU-8852552 https://reactome.org/PathwayBrowser/#/R-MMU-8852552 MST1R autophosphorylates IEA Mus musculus 456216 R-MMU-8853419 https://reactome.org/PathwayBrowser/#/R-MMU-8853419 TPX2 promotes AURKA autophosphorylation IEA Mus musculus 456216 R-MMU-8853444 https://reactome.org/PathwayBrowser/#/R-MMU-8853444 AURKA phosphorylates PHLDA1 IEA Mus musculus 456216 R-MMU-8853774 https://reactome.org/PathwayBrowser/#/R-MMU-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Mus musculus 456216 R-MMU-8853792 https://reactome.org/PathwayBrowser/#/R-MMU-8853792 RET tyrosine phosphorylation IEA Mus musculus 456216 R-MMU-8854908 https://reactome.org/PathwayBrowser/#/R-MMU-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Mus musculus 456216 R-MMU-8855237 https://reactome.org/PathwayBrowser/#/R-MMU-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Mus musculus 456216 R-MMU-8856813 https://reactome.org/PathwayBrowser/#/R-MMU-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Mus musculus 456216 R-MMU-8857555 https://reactome.org/PathwayBrowser/#/R-MMU-8857555 EGFR phosphorylates GPNMB IEA Mus musculus 456216 R-MMU-8857577 https://reactome.org/PathwayBrowser/#/R-MMU-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Mus musculus 456216 R-MMU-8857583 https://reactome.org/PathwayBrowser/#/R-MMU-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Mus musculus 456216 R-MMU-8857925 https://reactome.org/PathwayBrowser/#/R-MMU-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Mus musculus 456216 R-MMU-8865774 https://reactome.org/PathwayBrowser/#/R-MMU-8865774 TTLLs polyglutamylate tubulin IEA Mus musculus 456216 R-MMU-8866268 https://reactome.org/PathwayBrowser/#/R-MMU-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Mus musculus 456216 R-MMU-8866542 https://reactome.org/PathwayBrowser/#/R-MMU-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Mus musculus 456216 R-MMU-8867041 https://reactome.org/PathwayBrowser/#/R-MMU-8867041 EGFR phosphorylates EPS15 IEA Mus musculus 456216 R-MMU-8867370 https://reactome.org/PathwayBrowser/#/R-MMU-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Mus musculus 456216 R-MMU-8868066 https://reactome.org/PathwayBrowser/#/R-MMU-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Mus musculus 456216 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 456216 R-MMU-8868118 https://reactome.org/PathwayBrowser/#/R-MMU-8868118 MAPK12 phosphorylates PTPN3 IEA Mus musculus 456216 R-MMU-8868331 https://reactome.org/PathwayBrowser/#/R-MMU-8868331 Cdk5:p25 phosphorylates Golga2 TAS Mus musculus 456216 R-MMU-8868356 https://reactome.org/PathwayBrowser/#/R-MMU-8868356 Cdk5:p25 phosphorylates lamin A TAS Mus musculus 456216 R-MMU-8868383 https://reactome.org/PathwayBrowser/#/R-MMU-8868383 Cdk5:p25 phosphorylates lamin B1 TAS Mus musculus 456216 R-MMU-8868583 https://reactome.org/PathwayBrowser/#/R-MMU-8868583 Cdk5:p25 phosphorylates Prdx1 TAS Mus musculus 456216 R-MMU-8868589 https://reactome.org/PathwayBrowser/#/R-MMU-8868589 Cdk5:p25 phosphorylates Prdx2 TAS Mus musculus 456216 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 456216 R-MMU-8868677 https://reactome.org/PathwayBrowser/#/R-MMU-8868677 Cdk5:p25 phosphorylates Jun TAS Mus musculus 456216 R-MMU-8869606 https://reactome.org/PathwayBrowser/#/R-MMU-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Mus musculus 456216 R-MMU-8869607 https://reactome.org/PathwayBrowser/#/R-MMU-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Mus musculus 456216 R-MMU-8869627 https://reactome.org/PathwayBrowser/#/R-MMU-8869627 NMRK2 phosphorylates NR to yield NMN IEA Mus musculus 456216 R-MMU-8869633 https://reactome.org/PathwayBrowser/#/R-MMU-8869633 NMRK1 phosphorylates NR to yield NMN IEA Mus musculus 456216 R-MMU-8871373 https://reactome.org/PathwayBrowser/#/R-MMU-8871373 BMX phosphorylates RUFY1 IEA Mus musculus 456216 R-MMU-8873929 https://reactome.org/PathwayBrowser/#/R-MMU-8873929 Casein kinase II phosphorylates STARD10 IEA Mus musculus 456216 R-MMU-8874078 https://reactome.org/PathwayBrowser/#/R-MMU-8874078 PTK2 autophosphorylates IEA Mus musculus 456216 R-MMU-8874080 https://reactome.org/PathwayBrowser/#/R-MMU-8874080 SRC phosphorylates PTK2 IEA Mus musculus 456216 R-MMU-8874082 https://reactome.org/PathwayBrowser/#/R-MMU-8874082 MET phosphorylates PTK2 IEA Mus musculus 456216 R-MMU-8875451 https://reactome.org/PathwayBrowser/#/R-MMU-8875451 MET phosphorylates CBL IEA Mus musculus 456216 R-MMU-8875817 https://reactome.org/PathwayBrowser/#/R-MMU-8875817 MET phosphorylates STAT3 IEA Mus musculus 456216 R-MMU-8876446 https://reactome.org/PathwayBrowser/#/R-MMU-8876446 p-ULK1 phosphorylates DENND3 IEA Mus musculus 456216 R-MMU-8876889 https://reactome.org/PathwayBrowser/#/R-MMU-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 456216 R-MMU-8877691 https://reactome.org/PathwayBrowser/#/R-MMU-8877691 MAP2K6 phosphorylates PIP4K2B IEA Mus musculus 456216 R-MMU-8878050 https://reactome.org/PathwayBrowser/#/R-MMU-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Mus musculus 456216 R-MMU-8878054 https://reactome.org/PathwayBrowser/#/R-MMU-8878054 HIPK2 phosphorylates RUNX1 IEA Mus musculus 456216 R-MMU-8931653 https://reactome.org/PathwayBrowser/#/R-MMU-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Mus musculus 456216 R-MMU-8932375 https://reactome.org/PathwayBrowser/#/R-MMU-8932375 CK2 phosphorylates Nrf2 TAS Mus musculus 456216 R-MMU-8933446 https://reactome.org/PathwayBrowser/#/R-MMU-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Mus musculus 456216 R-MMU-8934446 https://reactome.org/PathwayBrowser/#/R-MMU-8934446 Activated PKC phosphorylates SHC1 IEA Mus musculus 456216 R-MMU-8937738 https://reactome.org/PathwayBrowser/#/R-MMU-8937738 Src phosphorylates Runx1 TAS Mus musculus 456216 R-MMU-8937807 https://reactome.org/PathwayBrowser/#/R-MMU-8937807 SRC phosphorylates RUNX3 IEA Mus musculus 456216 R-MMU-8940100 https://reactome.org/PathwayBrowser/#/R-MMU-8940100 CDK1 phosphorylates VCPIP1 IEA Mus musculus 456216 R-MMU-8942575 https://reactome.org/PathwayBrowser/#/R-MMU-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Mus musculus 456216 R-MMU-8942607 https://reactome.org/PathwayBrowser/#/R-MMU-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Mus musculus 456216 R-MMU-8942836 https://reactome.org/PathwayBrowser/#/R-MMU-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Mus musculus 456216 R-MMU-8944454 https://reactome.org/PathwayBrowser/#/R-MMU-8944454 mTORC1 phosphorylates MAF1 IEA Mus musculus 456216 R-MMU-8948039 https://reactome.org/PathwayBrowser/#/R-MMU-8948039 FUNDC1 is phosphorylated by CK2 IEA Mus musculus 456216 R-MMU-8948143 https://reactome.org/PathwayBrowser/#/R-MMU-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Mus musculus 456216 R-MMU-8948146 https://reactome.org/PathwayBrowser/#/R-MMU-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Mus musculus 456216 R-MMU-8948757 https://reactome.org/PathwayBrowser/#/R-MMU-8948757 AKT phosphorylates MKRN1 IEA Mus musculus 456216 R-MMU-8950269 https://reactome.org/PathwayBrowser/#/R-MMU-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Mus musculus 456216 R-MMU-8950340 https://reactome.org/PathwayBrowser/#/R-MMU-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Mus musculus 456216 R-MMU-8950405 https://reactome.org/PathwayBrowser/#/R-MMU-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Mus musculus 456216 R-MMU-8950423 https://reactome.org/PathwayBrowser/#/R-MMU-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Mus musculus 456216 R-MMU-8950453 https://reactome.org/PathwayBrowser/#/R-MMU-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Mus musculus 456216 R-MMU-8950485 https://reactome.org/PathwayBrowser/#/R-MMU-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Mus musculus 456216 R-MMU-8950537 https://reactome.org/PathwayBrowser/#/R-MMU-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Mus musculus 456216 R-MMU-8950612 https://reactome.org/PathwayBrowser/#/R-MMU-8950612 Jak2, Tyk2 in Il12b:Il23a:Il12rb1:Tyk2:Il23r:Jak2 are phosphorylated TAS Mus musculus 456216 R-MMU-8950679 https://reactome.org/PathwayBrowser/#/R-MMU-8950679 Il23r from Il23:Il23 receptor complex is phosphorylated TAS Mus musculus 456216 R-MMU-8950757 https://reactome.org/PathwayBrowser/#/R-MMU-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Mus musculus 456216 R-MMU-8952289 https://reactome.org/PathwayBrowser/#/R-MMU-8952289 FAM20C phosphorylates FAM20C substrates IEA Mus musculus 456216 R-MMU-8954327 https://reactome.org/PathwayBrowser/#/R-MMU-8954327 UCKL1 phosphorylates urindine, cytidine IEA Mus musculus 456216 R-MMU-8955030 https://reactome.org/PathwayBrowser/#/R-MMU-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Mus musculus 456216 R-MMU-8955844 https://reactome.org/PathwayBrowser/#/R-MMU-8955844 RBKS phosphorylates ribose to R5P IEA Mus musculus 456216 R-MMU-8956659 https://reactome.org/PathwayBrowser/#/R-MMU-8956659 ABL1 phosphorylates YAP1 IEA Mus musculus 456216 R-MMU-8959719 https://reactome.org/PathwayBrowser/#/R-MMU-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Mus musculus 456216 R-MMU-8964242 https://reactome.org/PathwayBrowser/#/R-MMU-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Mus musculus 456216 R-MMU-8982163 https://reactome.org/PathwayBrowser/#/R-MMU-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Mus musculus 456216 R-MMU-8983059 https://reactome.org/PathwayBrowser/#/R-MMU-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Mus musculus 456216 R-MMU-8983063 https://reactome.org/PathwayBrowser/#/R-MMU-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Mus musculus 456216 R-MMU-8983294 https://reactome.org/PathwayBrowser/#/R-MMU-8983294 Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1 TAS Mus musculus 456216 R-MMU-8983300 https://reactome.org/PathwayBrowser/#/R-MMU-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Mus musculus 456216 R-MMU-8983371 https://reactome.org/PathwayBrowser/#/R-MMU-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Mus musculus 456216 R-MMU-8983834 https://reactome.org/PathwayBrowser/#/R-MMU-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Mus musculus 456216 R-MMU-8983835 https://reactome.org/PathwayBrowser/#/R-MMU-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Mus musculus 456216 R-MMU-8983870 https://reactome.org/PathwayBrowser/#/R-MMU-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Mus musculus 456216 R-MMU-8983872 https://reactome.org/PathwayBrowser/#/R-MMU-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Mus musculus 456216 R-MMU-8984012 https://reactome.org/PathwayBrowser/#/R-MMU-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Mus musculus 456216 R-MMU-8984014 https://reactome.org/PathwayBrowser/#/R-MMU-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Mus musculus 456216 R-MMU-8985914 https://reactome.org/PathwayBrowser/#/R-MMU-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Mus musculus 456216 R-MMU-8985973 https://reactome.org/PathwayBrowser/#/R-MMU-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Mus musculus 456216 R-MMU-8985988 https://reactome.org/PathwayBrowser/#/R-MMU-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Mus musculus 456216 R-MMU-8986985 https://reactome.org/PathwayBrowser/#/R-MMU-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Mus musculus 456216 R-MMU-8986994 https://reactome.org/PathwayBrowser/#/R-MMU-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Mus musculus 456216 R-MMU-8986995 https://reactome.org/PathwayBrowser/#/R-MMU-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Mus musculus 456216 R-MMU-8987012 https://reactome.org/PathwayBrowser/#/R-MMU-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Mus musculus 456216 R-MMU-8987040 https://reactome.org/PathwayBrowser/#/R-MMU-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Mus musculus 456216 R-MMU-8987042 https://reactome.org/PathwayBrowser/#/R-MMU-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Mus musculus 456216 R-MMU-8987070 https://reactome.org/PathwayBrowser/#/R-MMU-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Mus musculus 456216 R-MMU-8987084 https://reactome.org/PathwayBrowser/#/R-MMU-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Mus musculus 456216 R-MMU-8987096 https://reactome.org/PathwayBrowser/#/R-MMU-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Mus musculus 456216 R-MMU-8987129 https://reactome.org/PathwayBrowser/#/R-MMU-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Mus musculus 456216 R-MMU-8987141 https://reactome.org/PathwayBrowser/#/R-MMU-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Mus musculus 456216 R-MMU-8987150 https://reactome.org/PathwayBrowser/#/R-MMU-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Mus musculus 456216 R-MMU-8987179 https://reactome.org/PathwayBrowser/#/R-MMU-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Mus musculus 456216 R-MMU-8987202 https://reactome.org/PathwayBrowser/#/R-MMU-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Mus musculus 456216 R-MMU-8987255 https://reactome.org/PathwayBrowser/#/R-MMU-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Mus musculus 456216 R-MMU-9005848 https://reactome.org/PathwayBrowser/#/R-MMU-9005848 Active Prkaca and CaMK IV phosphorylate Mecp2 at T308 TAS Mus musculus 456216 R-MMU-9006327 https://reactome.org/PathwayBrowser/#/R-MMU-9006327 Phospho-Jak2 phosphorylates Epor TAS Mus musculus 456216 R-MMU-9006329 https://reactome.org/PathwayBrowser/#/R-MMU-9006329 Jak2 transphosphorylates and is activated in response to Erythropoietin TAS Mus musculus 456216 R-MMU-9006466 https://reactome.org/PathwayBrowser/#/R-MMU-9006466 Stat4 is phosphorylated by p-Jak2 and/or p-Y-Tyk2 after Il12:Il12r interaction TAS Mus musculus 456216 R-MMU-9006850 https://reactome.org/PathwayBrowser/#/R-MMU-9006850 IL21 receptor JAK phosphorylation IEA Mus musculus 456216 R-MMU-9006870 https://reactome.org/PathwayBrowser/#/R-MMU-9006870 IL21 receptor STAT phosphorylation IEA Mus musculus 456216 R-MMU-9007015 https://reactome.org/PathwayBrowser/#/R-MMU-9007015 Mecp2 is phosphorylated at S421 TAS Mus musculus 456216 R-MMU-9007137 https://reactome.org/PathwayBrowser/#/R-MMU-9007137 Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1:Grb2:Gab2 phosphorylates Gab2 TAS Mus musculus 456216 R-MMU-9007539 https://reactome.org/PathwayBrowser/#/R-MMU-9007539 CHEK1 phosphorylates E2F6 IEA Mus musculus 456216 R-MMU-9008043 https://reactome.org/PathwayBrowser/#/R-MMU-9008043 MAPK8 phosphorylation IEA Mus musculus 456216 R-MMU-9008412 https://reactome.org/PathwayBrowser/#/R-MMU-9008412 CDK4 phosphorylates RUNX2 IEA Mus musculus 456216 R-MMU-9008684 https://reactome.org/PathwayBrowser/#/R-MMU-9008684 TBK1 phosphorylation IEA Mus musculus 456216 R-MMU-9009072 https://reactome.org/PathwayBrowser/#/R-MMU-9009072 STAT3 phosphorylation IEA Mus musculus 456216 R-MMU-9009282 https://reactome.org/PathwayBrowser/#/R-MMU-9009282 CDK1 phosphorylates RUNX2 IEA Mus musculus 456216 R-MMU-9009867 https://reactome.org/PathwayBrowser/#/R-MMU-9009867 Il2rb and Il2rg are phosphorylated TAS Mus musculus 456216 R-MMU-9011252 https://reactome.org/PathwayBrowser/#/R-MMU-9011252 Src phosphorylates Robo3.1 in response to Ntn1 TAS Mus musculus 456216 R-MMU-9012319 https://reactome.org/PathwayBrowser/#/R-MMU-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Mus musculus 456216 R-MMU-9012653 https://reactome.org/PathwayBrowser/#/R-MMU-9012653 Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2 phosphorylates Stat5 TAS Mus musculus 456216 R-MMU-9018572 https://reactome.org/PathwayBrowser/#/R-MMU-9018572 EGFR phosphorylates NOTCH3 IEA Mus musculus 456216 R-MMU-9021357 https://reactome.org/PathwayBrowser/#/R-MMU-9021357 PRKCI phosphorylates ELF3 IEA Mus musculus 456216 R-MMU-9021609 https://reactome.org/PathwayBrowser/#/R-MMU-9021609 ESR-associated SRC autophosphorylates IEA Mus musculus 456216 R-MMU-9021627 https://reactome.org/PathwayBrowser/#/R-MMU-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 456216 R-MMU-9022314 https://reactome.org/PathwayBrowser/#/R-MMU-9022314 HIPK2 phosphorylates MECP2 IEA Mus musculus 456216 R-MMU-9023138 https://reactome.org/PathwayBrowser/#/R-MMU-9023138 Aurkb phosphorylates Mecp2 at S421 TAS Mus musculus 456216 R-MMU-9027272 https://reactome.org/PathwayBrowser/#/R-MMU-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Mus musculus 456216 R-MMU-9027273 https://reactome.org/PathwayBrowser/#/R-MMU-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Mus musculus 456216 R-MMU-9027429 https://reactome.org/PathwayBrowser/#/R-MMU-9027429 Lyn phosphorylates Plcg1,2 in Epo:phospho-Epor:phospho-Jak2:Lyn:Irs2:Plcg1,2 TAS Mus musculus 456216 R-MMU-9029147 https://reactome.org/PathwayBrowser/#/R-MMU-9029147 Jak2 phosphorylates Shc1 in Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef:Shc1 TAS Mus musculus 456216 R-MMU-9029162 https://reactome.org/PathwayBrowser/#/R-MMU-9029162 Jak2 phosphorylates Vav1 in Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1:p-Y-Shc1:Grb2-1:Vav1 TAS Mus musculus 456216 R-MMU-9031553 https://reactome.org/PathwayBrowser/#/R-MMU-9031553 Activated Ntrk2 activates PI3K signaling TAS Mus musculus 456216 R-MMU-9033499 https://reactome.org/PathwayBrowser/#/R-MMU-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Mus musculus 456216 R-MMU-9034714 https://reactome.org/PathwayBrowser/#/R-MMU-9034714 NTRK3 dimers trans-autophosphorylate IEA Mus musculus 456216 R-MMU-9038161 https://reactome.org/PathwayBrowser/#/R-MMU-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Mus musculus 456216 R-MMU-909552 https://reactome.org/PathwayBrowser/#/R-MMU-909552 Phosphorylation of STAT1 at Ser727 IEA Mus musculus 456216 R-MMU-909718 https://reactome.org/PathwayBrowser/#/R-MMU-909718 Formation of p-STAT1 homodimer IEA Mus musculus 456216 R-MMU-909729 https://reactome.org/PathwayBrowser/#/R-MMU-909729 Activation of JAK kinases IEA Mus musculus 456216 R-MMU-909730 https://reactome.org/PathwayBrowser/#/R-MMU-909730 Phosphorylation of INFAR1 by TYK2 IEA Mus musculus 456216 R-MMU-909732 https://reactome.org/PathwayBrowser/#/R-MMU-909732 Phosphorylation of STAT2 IEA Mus musculus 456216 R-MMU-912423 https://reactome.org/PathwayBrowser/#/R-MMU-912423 Atr Phosphorylates Histone H2A.X at Unsynapsed Regions TAS Mus musculus 456216 R-MMU-912527 https://reactome.org/PathwayBrowser/#/R-MMU-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Mus musculus 456216 R-MMU-913996 https://reactome.org/PathwayBrowser/#/R-MMU-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Mus musculus 456216 R-MMU-917693 https://reactome.org/PathwayBrowser/#/R-MMU-917693 ESCRT Disassembly IEA Mus musculus 456216 R-MMU-917841 https://reactome.org/PathwayBrowser/#/R-MMU-917841 Acidification of Tf:TfR1 containing endosome IEA Mus musculus 456216 R-MMU-917979 https://reactome.org/PathwayBrowser/#/R-MMU-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-927889 https://reactome.org/PathwayBrowser/#/R-MMU-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Mus musculus 456216 R-MMU-934559 https://reactome.org/PathwayBrowser/#/R-MMU-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Mus musculus 456216 R-MMU-936802 https://reactome.org/PathwayBrowser/#/R-MMU-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Mus musculus 456216 R-MMU-936883 https://reactome.org/PathwayBrowser/#/R-MMU-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Mus musculus 456216 R-MMU-936895 https://reactome.org/PathwayBrowser/#/R-MMU-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Mus musculus 456216 R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 456216 R-MMU-936951 https://reactome.org/PathwayBrowser/#/R-MMU-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Mus musculus 456216 R-MMU-936991 https://reactome.org/PathwayBrowser/#/R-MMU-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Mus musculus 456216 R-MMU-937034 https://reactome.org/PathwayBrowser/#/R-MMU-937034 IRAK1 phosphorylates Pellino IEA Mus musculus 456216 R-MMU-937311 https://reactome.org/PathwayBrowser/#/R-MMU-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Mus musculus 456216 R-MMU-939763 https://reactome.org/PathwayBrowser/#/R-MMU-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Mus musculus 456216 R-MMU-947591 https://reactome.org/PathwayBrowser/#/R-MMU-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Mus musculus 456216 R-MMU-9603420 https://reactome.org/PathwayBrowser/#/R-MMU-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Mus musculus 456216 R-MMU-9604328 https://reactome.org/PathwayBrowser/#/R-MMU-9604328 AKT1 phosphorylates NOTCH4 IEA Mus musculus 456216 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 456216 R-MMU-9606621 https://reactome.org/PathwayBrowser/#/R-MMU-9606621 Gab2 in Active Flt3:Grb2:Gab2 is phosphorylated TAS Mus musculus 456216 R-MMU-9606884 https://reactome.org/PathwayBrowser/#/R-MMU-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Mus musculus 456216 R-MMU-9607032 https://reactome.org/PathwayBrowser/#/R-MMU-9607032 Lyn, p-Syk phosphorylate Btk TAS Mus musculus 456216 R-MMU-9607033 https://reactome.org/PathwayBrowser/#/R-MMU-9607033 Btk autophosphorylates TAS Mus musculus 456216 R-MMU-9607042 https://reactome.org/PathwayBrowser/#/R-MMU-9607042 Cd19 is phosphorylated TAS Mus musculus 456216 R-MMU-9610153 https://reactome.org/PathwayBrowser/#/R-MMU-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Mus musculus 456216 R-MMU-9610156 https://reactome.org/PathwayBrowser/#/R-MMU-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Mus musculus 456216 R-MMU-9610163 https://reactome.org/PathwayBrowser/#/R-MMU-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Mus musculus 456216 R-MMU-9610641 https://reactome.org/PathwayBrowser/#/R-MMU-9610641 Kif17 transports GluN1:GluN2B (Grin1:Grin2b) NMDA receptors to the plasma membrane TAS Mus musculus 456216 R-MMU-9612501 https://reactome.org/PathwayBrowser/#/R-MMU-9612501 SGK phosphorylates CREB1 IEA Mus musculus 456216 R-MMU-9612509 https://reactome.org/PathwayBrowser/#/R-MMU-9612509 SGK phosphorylates SRF IEA Mus musculus 456216 R-MMU-9619355 https://reactome.org/PathwayBrowser/#/R-MMU-9619355 CaMKK autophosphorylates in the cytosol IEA Mus musculus 456216 R-MMU-9624526 https://reactome.org/PathwayBrowser/#/R-MMU-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Mus musculus 456216 R-MMU-9624800 https://reactome.org/PathwayBrowser/#/R-MMU-9624800 CDK1 phosphorylates LBR IEA Mus musculus 456216 R-MMU-9625487 https://reactome.org/PathwayBrowser/#/R-MMU-9625487 PTK2 autophosphorylates downstream of EGFR IEA Mus musculus 456216 R-MMU-9626817 https://reactome.org/PathwayBrowser/#/R-MMU-9626817 PKC phosphorylates NCF1 IEA Mus musculus 456216 R-MMU-9626832 https://reactome.org/PathwayBrowser/#/R-MMU-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Mus musculus 456216 R-MMU-9626880 https://reactome.org/PathwayBrowser/#/R-MMU-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Mus musculus 456216 R-MMU-9627089 https://reactome.org/PathwayBrowser/#/R-MMU-9627089 CASP9 is phosphorylated at T412 IEA Mus musculus 456216 R-MMU-9632858 https://reactome.org/PathwayBrowser/#/R-MMU-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Mus musculus 456216 R-MMU-9632868 https://reactome.org/PathwayBrowser/#/R-MMU-9632868 CDKN1B is phosphorylated in response to estrogen IEA Mus musculus 456216 R-MMU-9633504 https://reactome.org/PathwayBrowser/#/R-MMU-9633504 Eif2ak4 phosphorylates Eif2s1 IEA Mus musculus 456216 R-MMU-9633741 https://reactome.org/PathwayBrowser/#/R-MMU-9633741 Eif2ak4 dimer autophosphorylates IEA Mus musculus 456216 R-MMU-9634702 https://reactome.org/PathwayBrowser/#/R-MMU-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Mus musculus 456216 R-MMU-9645136 https://reactome.org/PathwayBrowser/#/R-MMU-9645136 Activator phosphorylates Stat5 TAS Mus musculus 456216 R-MMU-9645442 https://reactome.org/PathwayBrowser/#/R-MMU-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Mus musculus 456216 R-MMU-9645535 https://reactome.org/PathwayBrowser/#/R-MMU-9645535 ALPK1 phosphorylates TIFA IEA Mus musculus 456216 R-MMU-964958 https://reactome.org/PathwayBrowser/#/R-MMU-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Mus musculus 456216 R-MMU-964962 https://reactome.org/PathwayBrowser/#/R-MMU-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Mus musculus 456216 R-MMU-964970 https://reactome.org/PathwayBrowser/#/R-MMU-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Mus musculus 456216 R-MMU-9650858 https://reactome.org/PathwayBrowser/#/R-MMU-9650858 Meglitinides bind ABCC8 IEA Mus musculus 456216 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 456216 R-MMU-9653503 https://reactome.org/PathwayBrowser/#/R-MMU-9653503 KRAS4B is phosphorylated on serine 181 IEA Mus musculus 456216 R-MMU-9655549 https://reactome.org/PathwayBrowser/#/R-MMU-9655549 p-T-Eif2ak1:ferriheme dimer autophosphorylates TAS Mus musculus 456216 R-MMU-9655565 https://reactome.org/PathwayBrowser/#/R-MMU-9655565 p-T-Eif2ak1 phosphorylates Eif2s1 (eIF2-alpha) TAS Mus musculus 456216 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 456216 R-MMU-9661417 https://reactome.org/PathwayBrowser/#/R-MMU-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-9668419 https://reactome.org/PathwayBrowser/#/R-MMU-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Mus musculus 456216 R-MMU-9668464 https://reactome.org/PathwayBrowser/#/R-MMU-9668464 Atp2b2 (PMCA2) transports Ca2+ from the cytosol to the extracellular region TAS Mus musculus 456216 R-MMU-9674900 https://reactome.org/PathwayBrowser/#/R-MMU-9674900 Csf3:Csf3r induces phosphorylation of Jak1 TAS Mus musculus 456216 R-MMU-9674908 https://reactome.org/PathwayBrowser/#/R-MMU-9674908 p-Y-Jak1,2 phosphorylates Stat1,3,5 in Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2:Stat1,3,5 TAS Mus musculus 456216 R-MMU-9674921 https://reactome.org/PathwayBrowser/#/R-MMU-9674921 p-Y-Jak1 phosphorylates Csf3r in Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2 TAS Mus musculus 456216 R-MMU-9680646 https://reactome.org/PathwayBrowser/#/R-MMU-9680646 Pik3r11:Pik3ca,b,d (Pi3k), Plcg2 (PLCgamma2), Grb2:Sos1, Shc1 (Shc), Ptpn11 (Shp2), Grb2:Gab2, Grb2:Gab3, Grap2 (MONA), Cbl:Grb2, Inpp5d (SHIP1), Inppl1 (SHIP2) bind p-8Y-Csf1r and are activated TAS Mus musculus 456216 R-MMU-9680706 https://reactome.org/PathwayBrowser/#/R-MMU-9680706 Csf1r trans-autophosphorylates on multiple tyrosine residues TAS Mus musculus 456216 R-MMU-9682182 https://reactome.org/PathwayBrowser/#/R-MMU-9682182 Csf1r-associated PI3K phosphorylates phosphatidylinositol 4,5-bisphosphate TAS Mus musculus 456216 R-MMU-9684118 https://reactome.org/PathwayBrowser/#/R-MMU-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Mus musculus 456216 R-MMU-9686521 https://reactome.org/PathwayBrowser/#/R-MMU-9686521 CDK2:CCNA phosphorylates TERF2 IEA Mus musculus 456216 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 456216 R-MMU-9699578 https://reactome.org/PathwayBrowser/#/R-MMU-9699578 Active FLT3 phosphorylates CDKN1B IEA Mus musculus 456216 R-MMU-9699579 https://reactome.org/PathwayBrowser/#/R-MMU-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Mus musculus 456216 R-MMU-9700168 https://reactome.org/PathwayBrowser/#/R-MMU-9700168 Active ALK phosphorylates IRS1 IEA Mus musculus 456216 R-MMU-9700171 https://reactome.org/PathwayBrowser/#/R-MMU-9700171 Active ALK phosphorylates PLCG1 IEA Mus musculus 456216 R-MMU-9700175 https://reactome.org/PathwayBrowser/#/R-MMU-9700175 Active ALK phosphorylates SHC1 IEA Mus musculus 456216 R-MMU-9701488 https://reactome.org/PathwayBrowser/#/R-MMU-9701488 Active ALK phosphorylates JAK3 IEA Mus musculus 456216 R-MMU-9706344 https://reactome.org/PathwayBrowser/#/R-MMU-9706344 FLT3 phosphorylates GRB10 IEA Mus musculus 456216 R-MMU-9706350 https://reactome.org/PathwayBrowser/#/R-MMU-9706350 FLT3 phosphorylates CBL IEA Mus musculus 456216 R-MMU-9706399 https://reactome.org/PathwayBrowser/#/R-MMU-9706399 RHOBTB3 hydrolyzes ATP IEA Mus musculus 456216 R-MMU-9709373 https://reactome.org/PathwayBrowser/#/R-MMU-9709373 Ptk6 phosphorylates Stat3 TAS Mus musculus 456216 R-MMU-9727198 https://reactome.org/PathwayBrowser/#/R-MMU-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Mus musculus 456216 R-MMU-9731111 https://reactome.org/PathwayBrowser/#/R-MMU-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Mus musculus 456216 R-MMU-9732738 https://reactome.org/PathwayBrowser/#/R-MMU-9732738 JAK1-mediated phosphorylation of RAF1 IEA Mus musculus 456216 R-MMU-9732753 https://reactome.org/PathwayBrowser/#/R-MMU-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Mus musculus 456216 R-MMU-9734547 https://reactome.org/PathwayBrowser/#/R-MMU-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Mus musculus 456216 R-MMU-9734687 https://reactome.org/PathwayBrowser/#/R-MMU-9734687 ORC6 is phosphorylated on T195 IEA Mus musculus 456216 R-MMU-9748949 https://reactome.org/PathwayBrowser/#/R-MMU-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Mus musculus 456216 R-MMU-9748963 https://reactome.org/PathwayBrowser/#/R-MMU-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Mus musculus 456216 R-MMU-9748969 https://reactome.org/PathwayBrowser/#/R-MMU-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Mus musculus 456216 R-MMU-9748999 https://reactome.org/PathwayBrowser/#/R-MMU-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Mus musculus 456216 R-MMU-9750546 https://reactome.org/PathwayBrowser/#/R-MMU-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-9750617 https://reactome.org/PathwayBrowser/#/R-MMU-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-9750656 https://reactome.org/PathwayBrowser/#/R-MMU-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Mus musculus 456216 R-MMU-975103 https://reactome.org/PathwayBrowser/#/R-MMU-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Mus musculus 456216 R-MMU-975139 https://reactome.org/PathwayBrowser/#/R-MMU-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Mus musculus 456216 R-MMU-9753278 https://reactome.org/PathwayBrowser/#/R-MMU-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 456216 R-MMU-9753283 https://reactome.org/PathwayBrowser/#/R-MMU-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 456216 R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 456216 R-MMU-9754974 https://reactome.org/PathwayBrowser/#/R-MMU-9754974 ADK phosphorylates RBV IEA Mus musculus 456216 R-MMU-9755013 https://reactome.org/PathwayBrowser/#/R-MMU-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Mus musculus 456216 R-MMU-9759206 https://reactome.org/PathwayBrowser/#/R-MMU-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Mus musculus 456216 R-MMU-9759454 https://reactome.org/PathwayBrowser/#/R-MMU-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Mus musculus 456216 R-MMU-9759461 https://reactome.org/PathwayBrowser/#/R-MMU-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Mus musculus 456216 R-MMU-9760094 https://reactome.org/PathwayBrowser/#/R-MMU-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Mus musculus 456216 R-MMU-9762094 https://reactome.org/PathwayBrowser/#/R-MMU-9762094 GSK3B phosphorylates p-NFE2L2 IEA Mus musculus 456216 R-MMU-9763891 https://reactome.org/PathwayBrowser/#/R-MMU-9763891 Src family kinases phosphorylate Cbl in Csf1 dimer:p-Y559-Csf1r dimer:Cbl TAS Mus musculus 456216 R-MMU-9763901 https://reactome.org/PathwayBrowser/#/R-MMU-9763901 Csf1r trans-autophosphoryates on tyrosine-559 TAS Mus musculus 456216 R-MMU-9769840 https://reactome.org/PathwayBrowser/#/R-MMU-9769840 Mapk1,(Mapk3) phosphorylate Npas4 TAS Mus musculus 456216 R-MMU-9770141 https://reactome.org/PathwayBrowser/#/R-MMU-9770141 Formation of the Spliceosomal C* complex IEA Mus musculus 456216 R-MMU-9770142 https://reactome.org/PathwayBrowser/#/R-MMU-9770142 Formation of the Spliceosomal B complex IEA Mus musculus 456216 R-MMU-9770145 https://reactome.org/PathwayBrowser/#/R-MMU-9770145 Formation of the Spliceosomal Bact complex IEA Mus musculus 456216 R-MMU-9773803 https://reactome.org/PathwayBrowser/#/R-MMU-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Mus musculus 456216 R-MMU-9794120 https://reactome.org/PathwayBrowser/#/R-MMU-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Mus musculus 456216 R-MMU-9794572 https://reactome.org/PathwayBrowser/#/R-MMU-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Mus musculus 456216 R-MMU-9796053 https://reactome.org/PathwayBrowser/#/R-MMU-9796053 PRKCI phosphorylates NFE2L2 IEA Mus musculus 456216 R-MMU-9796067 https://reactome.org/PathwayBrowser/#/R-MMU-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Mus musculus 456216 R-MMU-9815501 https://reactome.org/PathwayBrowser/#/R-MMU-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 IEA Mus musculus 456216 R-MMU-9817397 https://reactome.org/PathwayBrowser/#/R-MMU-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Mus musculus 456216 R-MMU-9818776 https://reactome.org/PathwayBrowser/#/R-MMU-9818776 Eif2ak3 phosphorylates Nfe2l2 TAS Mus musculus 456216 R-MMU-9818789 https://reactome.org/PathwayBrowser/#/R-MMU-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Mus musculus 456216 R-MMU-9819106 https://reactome.org/PathwayBrowser/#/R-MMU-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Mus musculus 456216 R-MMU-9821987 https://reactome.org/PathwayBrowser/#/R-MMU-9821987 Srpk1 phosphorylates Prm2 in Prm2:dsDNA TAS Mus musculus 456216 R-MMU-9821990 https://reactome.org/PathwayBrowser/#/R-MMU-9821990 Srpk1 phosphorylates Prm1 in Prm1:dsDNA TAS Mus musculus 456216 R-MMU-9823906 https://reactome.org/PathwayBrowser/#/R-MMU-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Mus musculus 456216 R-MMU-9824882 https://reactome.org/PathwayBrowser/#/R-MMU-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Mus musculus 456216 R-MMU-9824977 https://reactome.org/PathwayBrowser/#/R-MMU-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Mus musculus 456216 R-MMU-9824994 https://reactome.org/PathwayBrowser/#/R-MMU-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Mus musculus 456216 R-MMU-9824995 https://reactome.org/PathwayBrowser/#/R-MMU-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Mus musculus 456216 R-MMU-9824999 https://reactome.org/PathwayBrowser/#/R-MMU-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Mus musculus 456216 R-MMU-9825759 https://reactome.org/PathwayBrowser/#/R-MMU-9825759 MAPK-dependent phosphorylation of KARS IEA Mus musculus 456216 R-MMU-982807 https://reactome.org/PathwayBrowser/#/R-MMU-982807 JAK2 phosphorylation of GHR IEA Mus musculus 456216 R-MMU-982810 https://reactome.org/PathwayBrowser/#/R-MMU-982810 JAK2 phosphorylation IEA Mus musculus 456216 R-MMU-983144 https://reactome.org/PathwayBrowser/#/R-MMU-983144 Transport of Antigen peptide in to ER IEA Mus musculus 456216 R-MMU-983259 https://reactome.org/PathwayBrowser/#/R-MMU-983259 Kinesins move along microtubules consuming ATP IEA Mus musculus 456216 R-MMU-9836159 https://reactome.org/PathwayBrowser/#/R-MMU-9836159 p-PKR dimer phosphorylates DHX9 IEA Mus musculus 456216 R-MMU-9836184 https://reactome.org/PathwayBrowser/#/R-MMU-9836184 p-PKR dimer phosphorylates CDK1 IEA Mus musculus 456216 R-MMU-9836322 https://reactome.org/PathwayBrowser/#/R-MMU-9836322 p-PKR dimer phosphorylates MKK6 IEA Mus musculus 456216 R-MMU-9836362 https://reactome.org/PathwayBrowser/#/R-MMU-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Mus musculus 456216 R-MMU-9836383 https://reactome.org/PathwayBrowser/#/R-MMU-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Mus musculus 456216 R-MMU-9836404 https://reactome.org/PathwayBrowser/#/R-MMU-9836404 p-PKR dimer phosphorylates MAPT IEA Mus musculus 456216 R-MMU-9836435 https://reactome.org/PathwayBrowser/#/R-MMU-9836435 p-PKR dimer phosphorylates SNCA IEA Mus musculus 456216 R-MMU-9836515 https://reactome.org/PathwayBrowser/#/R-MMU-9836515 p-PKR dimer phosphorylates PTPN2 IEA Mus musculus 456216 R-MMU-9836617 https://reactome.org/PathwayBrowser/#/R-MMU-9836617 p-PKR dimer phosphorylates SPHK1 IEA Mus musculus 456216 R-MMU-9836664 https://reactome.org/PathwayBrowser/#/R-MMU-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Mus musculus 456216 R-MMU-983702 https://reactome.org/PathwayBrowser/#/R-MMU-983702 Phosphorylation of ITAMs of Ig-alpha (Cd79a) and Ig-beta (Cd79b) TAS Mus musculus 456216 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus 456216 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus 456216 R-MMU-9837333 https://reactome.org/PathwayBrowser/#/R-MMU-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Mus musculus 456216 R-MMU-9837337 https://reactome.org/PathwayBrowser/#/R-MMU-9837337 DCAKD phosphorylates DP-CoA IEA Mus musculus 456216 R-MMU-9838004 https://reactome.org/PathwayBrowser/#/R-MMU-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Mus musculus 456216 R-MMU-9838081 https://reactome.org/PathwayBrowser/#/R-MMU-9838081 LONP1 degrades mitochondrial matrix proteins IEA Mus musculus 456216 R-MMU-9838289 https://reactome.org/PathwayBrowser/#/R-MMU-9838289 CLPXP degrades mitochondrial matrix proteins IEA Mus musculus 456216 R-MMU-9838321 https://reactome.org/PathwayBrowser/#/R-MMU-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Mus musculus 456216 R-MMU-9839059 https://reactome.org/PathwayBrowser/#/R-MMU-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Mus musculus 456216 R-MMU-9839105 https://reactome.org/PathwayBrowser/#/R-MMU-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Mus musculus 456216 R-MMU-9839113 https://reactome.org/PathwayBrowser/#/R-MMU-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Mus musculus 456216 R-MMU-9842648 https://reactome.org/PathwayBrowser/#/R-MMU-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 IEA Mus musculus 456216 R-MMU-9842651 https://reactome.org/PathwayBrowser/#/R-MMU-9842651 Active LTK receptor phosphorylates SHC1 IEA Mus musculus 456216 R-MMU-9842666 https://reactome.org/PathwayBrowser/#/R-MMU-9842666 Active LTK phosphorylates IRS1 IEA Mus musculus 456216 R-MMU-9843721 https://reactome.org/PathwayBrowser/#/R-MMU-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Mus musculus 456216 R-MMU-9851972 https://reactome.org/PathwayBrowser/#/R-MMU-9851972 PLK1 phosphorylates FIRRM at S43 IEA Mus musculus 456216 R-MMU-9853369 https://reactome.org/PathwayBrowser/#/R-MMU-9853369 PLK1 phosphorylates FIRMM at S744 IEA Mus musculus 456216 R-MMU-9861642 https://reactome.org/PathwayBrowser/#/R-MMU-9861642 NEK1 phosphorylates ME1 IEA Mus musculus 456216 R-MMU-994137 https://reactome.org/PathwayBrowser/#/R-MMU-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Mus musculus 456216 R-MMU-994140 https://reactome.org/PathwayBrowser/#/R-MMU-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Mus musculus 456216 R-MTU-936583 https://reactome.org/PathwayBrowser/#/R-MTU-936583 APS is phosphorylated to PAPS TAS Mycobacterium tuberculosis 456216 R-MTU-936631 https://reactome.org/PathwayBrowser/#/R-MTU-936631 sulfate uptake in the cytosol TAS Mycobacterium tuberculosis 456216 R-MTU-964939 https://reactome.org/PathwayBrowser/#/R-MTU-964939 Phosphorylation of shikimate TAS Mycobacterium tuberculosis 456216 R-NUL-1181349 https://reactome.org/PathwayBrowser/#/R-NUL-1181349 Phosphorylation of Smad2 by Nodal Receptor TAS Homo sapiens 456216 R-NUL-1236944 https://reactome.org/PathwayBrowser/#/R-NUL-1236944 Translocation of antigenic peptides back to phagosomes via TAP TAS Gallus gallus 456216 R-NUL-1251929 https://reactome.org/PathwayBrowser/#/R-NUL-1251929 Plcg1 phosphorylation by P-ERBB2:P-EGFR TAS Homo sapiens 456216 R-NUL-1458902 https://reactome.org/PathwayBrowser/#/R-NUL-1458902 frog CK1gamma phosphorylates LRP5/6 TAS Homo sapiens 456216 R-NUL-1675886 https://reactome.org/PathwayBrowser/#/R-NUL-1675886 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the early endosome membrane TAS Mus musculus 456216 R-NUL-1675925 https://reactome.org/PathwayBrowser/#/R-NUL-1675925 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the late endosome membrane TAS Mus musculus 456216 R-NUL-1675982 https://reactome.org/PathwayBrowser/#/R-NUL-1675982 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the Golgi membrane TAS Mus musculus 456216 R-NUL-1676051 https://reactome.org/PathwayBrowser/#/R-NUL-1676051 PI is phosphorylated to PI5P by Pikfyve at the late endosome membrane TAS Mus musculus 456216 R-NUL-2065178 https://reactome.org/PathwayBrowser/#/R-NUL-2065178 CDK8 phosphorylates xNICD1 TAS Homo sapiens 456216 R-NUL-209060 https://reactome.org/PathwayBrowser/#/R-NUL-209060 Human APC is further phosphorylated by Murine GSK3beta TAS Homo sapiens 456216 R-NUL-209065 https://reactome.org/PathwayBrowser/#/R-NUL-209065 Human APC is further phosphorylated by Murine CKIepsilon TAS Homo sapiens 456216 R-NUL-209104 https://reactome.org/PathwayBrowser/#/R-NUL-209104 Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex TAS Homo sapiens 456216 R-NUL-209132 https://reactome.org/PathwayBrowser/#/R-NUL-209132 Human APC is initially phosphorylated by Murine CKIepsilon TAS Homo sapiens 456216 R-NUL-209144 https://reactome.org/PathwayBrowser/#/R-NUL-209144 Human APC is finally phosphorylated by Murine GSK3beta TAS Homo sapiens 456216 R-NUL-209146 https://reactome.org/PathwayBrowser/#/R-NUL-209146 Murine Axin1 is further phosphorylated by Human GSK3beta TAS Mus musculus 456216 R-NUL-2161165 https://reactome.org/PathwayBrowser/#/R-NUL-2161165 TGFBR2 phosphorylates Pard6a TAS Homo sapiens 456216 R-NUL-2422970 https://reactome.org/PathwayBrowser/#/R-NUL-2422970 Phosphorylation of Gorasp1, Golga2 and RAB1A by CDK1:CCNB TAS Homo sapiens 456216 R-NUL-2434198 https://reactome.org/PathwayBrowser/#/R-NUL-2434198 CDK1 phosphorylates Mastl TAS Homo sapiens 456216 R-NUL-3139045 https://reactome.org/PathwayBrowser/#/R-NUL-3139045 AKT phosphorylates Bad TAS Homo sapiens 456216 R-NUL-3245934 https://reactome.org/PathwayBrowser/#/R-NUL-3245934 Mapk1 (Erk2) phosphorylates ERF TAS Homo sapiens 456216 R-NUL-3299417 https://reactome.org/PathwayBrowser/#/R-NUL-3299417 MAP3K5 (ASK1) phosphorylates Map2k4(Sek1) TAS Homo sapiens 456216 R-NUL-3858478 https://reactome.org/PathwayBrowser/#/R-NUL-3858478 Rat Dvl is phosophorylated upon Wnt binding TAS Mus musculus 456216 R-NUL-3876071 https://reactome.org/PathwayBrowser/#/R-NUL-3876071 RPS6KA1/2/3 phosphorylates Cebpb on S273 TAS Homo sapiens 456216 R-NUL-389973 https://reactome.org/PathwayBrowser/#/R-NUL-389973 ADP is exchanged for ATP in the ADP:CCT/TriC:tubulin complex TAS Mus musculus 456216 R-NUL-391408 https://reactome.org/PathwayBrowser/#/R-NUL-391408 Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC TAS Mus musculus 456216 R-NUL-391434 https://reactome.org/PathwayBrowser/#/R-NUL-391434 Exchange of ADP for ATP in CCT/TriC:actin complex TAS Bos taurus 456216 R-NUL-391437 https://reactome.org/PathwayBrowser/#/R-NUL-391437 Hydrolysis of ATP and release of folded actin from CCT/TriC TAS Bos taurus 456216 R-NUL-391444 https://reactome.org/PathwayBrowser/#/R-NUL-391444 Actin/tubulin:prefoldin complex associates with CCT/TriC TAS Bos taurus 456216 R-NUL-391979 https://reactome.org/PathwayBrowser/#/R-NUL-391979 Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) TAS Mus musculus 456216 R-NUL-420398 https://reactome.org/PathwayBrowser/#/R-NUL-420398 Autophosphorylation of NCAM1 bound Fyn TAS Mus musculus 456216 R-NUL-421062 https://reactome.org/PathwayBrowser/#/R-NUL-421062 Myosin phosphatase inactivation by ROCK2 TAS Bos taurus 456216 R-NUL-421139 https://reactome.org/PathwayBrowser/#/R-NUL-421139 Limk1 phosphorylates Cfl1, inactivating it TAS Homo sapiens 456216 R-NUL-421724 https://reactome.org/PathwayBrowser/#/R-NUL-421724 Myosin regulatory light chain phosphorylation by Rock2 TAS Gallus gallus 456216 R-NUL-421733 https://reactome.org/PathwayBrowser/#/R-NUL-421733 ROCK1 phosphorylates LIMK2 (rat) TAS Homo sapiens 456216 R-NUL-428715 https://reactome.org/PathwayBrowser/#/R-NUL-428715 Activated human P2Y purinoceptor 1 binds mouse G-protein Gq TAS Homo sapiens 456216 R-NUL-437938 https://reactome.org/PathwayBrowser/#/R-NUL-437938 Syk phosphorylates VAV1 TAS Homo sapiens 456216 R-NUL-445066 https://reactome.org/PathwayBrowser/#/R-NUL-445066 Phosphorylation of L1 by p90rsk TAS Homo sapiens 456216 R-NUL-451681 https://reactome.org/PathwayBrowser/#/R-NUL-451681 Tpl2 phosphorylates Mek1, Sek1 TAS Mus musculus 456216 R-NUL-5610714 https://reactome.org/PathwayBrowser/#/R-NUL-5610714 GSK3 phosphorylates p-Gli2 TAS Mus musculus 456216 R-NUL-5610715 https://reactome.org/PathwayBrowser/#/R-NUL-5610715 CK1 phosphorylates p-Gli2 TAS Mus musculus 456216 R-NUL-5610740 https://reactome.org/PathwayBrowser/#/R-NUL-5610740 Pka phosphorylates GLI1 TAS Mus musculus 456216 R-NUL-5671959 https://reactome.org/PathwayBrowser/#/R-NUL-5671959 Activated Cit phosphorylates MRLCs of myosin II complex TAS Bos taurus 456216 R-NUL-804924 https://reactome.org/PathwayBrowser/#/R-NUL-804924 PKC (cow) phosphorylates G alpha z (rat) TAS Bos taurus 456216 R-NUL-8870566 https://reactome.org/PathwayBrowser/#/R-NUL-8870566 Cdk5:p25 phosphorylates FOXO3 TAS Homo sapiens 456216 R-NUL-8939977 https://reactome.org/PathwayBrowser/#/R-NUL-8939977 Activated AKT1 phosphorylates Runx2 TAS Homo sapiens 456216 R-NUL-8955873 https://reactome.org/PathwayBrowser/#/R-NUL-8955873 Polyglutamylase complex (Ttll1) polyglutamylates alpha subunits of tubulin TAS Homo sapiens 456216 R-NUL-9008636 https://reactome.org/PathwayBrowser/#/R-NUL-9008636 GSK3B phosphorylates Runx2 TAS Homo sapiens 456216 R-NUL-9009236 https://reactome.org/PathwayBrowser/#/R-NUL-9009236 Activated ERKs phosphorylate Runx2 TAS Homo sapiens 456216 R-NUL-9030372 https://reactome.org/PathwayBrowser/#/R-NUL-9030372 BDNF-bound Ntrk2 dimers trans-autophosphorylate TAS Homo sapiens 456216 R-NUL-9030397 https://reactome.org/PathwayBrowser/#/R-NUL-9030397 NTF3-bound Ntrk2 dimers trans-autophosphorylate TAS Homo sapiens 456216 R-NUL-9030427 https://reactome.org/PathwayBrowser/#/R-NUL-9030427 NTF4-bound Ntrk2 dimers trans-autophosphorylate TAS Homo sapiens 456216 R-NUL-9030450 https://reactome.org/PathwayBrowser/#/R-NUL-9030450 BDNF- or NTF4-activated Ntrk2 phosphorylates Plcg1 TAS Homo sapiens 456216 R-NUL-9031971 https://reactome.org/PathwayBrowser/#/R-NUL-9031971 Ntrk2 phosphorylates Frs2 TAS Homo sapiens 456216 R-NUL-9032423 https://reactome.org/PathwayBrowser/#/R-NUL-9032423 Ntrk2 phosphorylates FRS3 TAS Homo sapiens 456216 R-NUL-9032945 https://reactome.org/PathwayBrowser/#/R-NUL-9032945 Ntrk2 phosohorylates CDK5 TAS Homo sapiens 456216 R-NUL-9032961 https://reactome.org/PathwayBrowser/#/R-NUL-9032961 Cdk5 phosphorylates Ntrk2 TAS Homo sapiens 456216 R-NUL-9033333 https://reactome.org/PathwayBrowser/#/R-NUL-9033333 Ntrk2 promotes Tiam1 phosphorylation TAS Homo sapiens 456216 R-NUL-9034815 https://reactome.org/PathwayBrowser/#/R-NUL-9034815 Ntrk3 phosphorylates Plcg1 TAS Homo sapiens 456216 R-NUL-9036937 https://reactome.org/PathwayBrowser/#/R-NUL-9036937 Ntrk3 phosphorylates Shc1 TAS Homo sapiens 456216 R-NUL-9615367 https://reactome.org/PathwayBrowser/#/R-NUL-9615367 Prkaca phosphorylates Creb1 TAS Rattus norvegicus 456216 R-NUL-9616944 https://reactome.org/PathwayBrowser/#/R-NUL-9616944 Activated Ntrk3 stimulates PI3K activity TAS Mus musculus 456216 R-NUL-9619177 https://reactome.org/PathwayBrowser/#/R-NUL-9619177 Camkk2 phosphorylates CAMK4 TAS Homo sapiens 456216 R-NUL-9619396 https://reactome.org/PathwayBrowser/#/R-NUL-9619396 CAMKK1 phosphorylates CAMK1 TAS Homo sapiens 456216 R-NUL-9619413 https://reactome.org/PathwayBrowser/#/R-NUL-9619413 CAMKK2 phosphorylates Camk1 TAS Homo sapiens 456216 R-NUL-9619488 https://reactome.org/PathwayBrowser/#/R-NUL-9619488 Camkk2 phosphorylates AMPK TAS Rattus norvegicus 456216 R-NUL-9619534 https://reactome.org/PathwayBrowser/#/R-NUL-9619534 AMPK phosphorylates Mapt TAS Rattus norvegicus 456216 R-NUL-9619973 https://reactome.org/PathwayBrowser/#/R-NUL-9619973 MAPK1 phosphorylates Rps6ka1 TAS Homo sapiens 456216 R-NUL-9620024 https://reactome.org/PathwayBrowser/#/R-NUL-9620024 PDPK1 phosphorylates Rps6ka2 TAS Homo sapiens 456216 R-NUL-9700161 https://reactome.org/PathwayBrowser/#/R-NUL-9700161 p-7Y ALK dimer phosphorylates Frs2 TAS Homo sapiens 456216 R-NUL-9700655 https://reactome.org/PathwayBrowser/#/R-NUL-9700655 Active ALK phosphorylates Src TAS Homo sapiens 456216 R-NUL-9726861 https://reactome.org/PathwayBrowser/#/R-NUL-9726861 Src phosphorylates RHOU TAS Homo sapiens 456216 R-OCU-211638 https://reactome.org/PathwayBrowser/#/R-OCU-211638 Autophosphorylation of PAK-2p34 TAS Oryctolagus cuniculus 456216 R-OCU-213297 https://reactome.org/PathwayBrowser/#/R-OCU-213297 Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197 TAS Oryctolagus cuniculus 456216 R-OCU-9655594 https://reactome.org/PathwayBrowser/#/R-OCU-9655594 p-T-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) TAS Oryctolagus cuniculus 456216 R-PCH-2408503 https://reactome.org/PathwayBrowser/#/R-PCH-2408503 APSe is phosphorylated to PAPSe by Kaps TAS Penicillium chrysogenum 456216 R-PFA-1008248 https://reactome.org/PathwayBrowser/#/R-PFA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Plasmodium falciparum 456216 R-PFA-110133 https://reactome.org/PathwayBrowser/#/R-PFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Plasmodium falciparum 456216 R-PFA-110137 https://reactome.org/PathwayBrowser/#/R-PFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Plasmodium falciparum 456216 R-PFA-110138 https://reactome.org/PathwayBrowser/#/R-PFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 456216 R-PFA-110144 https://reactome.org/PathwayBrowser/#/R-PFA-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Plasmodium falciparum 456216 R-PFA-110145 https://reactome.org/PathwayBrowser/#/R-PFA-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Plasmodium falciparum 456216 R-PFA-111915 https://reactome.org/PathwayBrowser/#/R-PFA-111915 CAMK4 autophosphorylates IEA Plasmodium falciparum 456216 R-PFA-1369028 https://reactome.org/PathwayBrowser/#/R-PFA-1369028 ABCAs mediate lipid efflux IEA Plasmodium falciparum 456216 R-PFA-1369052 https://reactome.org/PathwayBrowser/#/R-PFA-1369052 ABCAs mediate lipid influx IEA Plasmodium falciparum 456216 R-PFA-1369065 https://reactome.org/PathwayBrowser/#/R-PFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Plasmodium falciparum 456216 R-PFA-1454916 https://reactome.org/PathwayBrowser/#/R-PFA-1454916 The ABCC family mediates organic anion transport IEA Plasmodium falciparum 456216 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 456216 R-PFA-1467466 https://reactome.org/PathwayBrowser/#/R-PFA-1467466 ABCA4 mediates atRAL transport IEA Plasmodium falciparum 456216 R-PFA-1483004 https://reactome.org/PathwayBrowser/#/R-PFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Plasmodium falciparum 456216 R-PFA-1483222 https://reactome.org/PathwayBrowser/#/R-PFA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Plasmodium falciparum 456216 R-PFA-156682 https://reactome.org/PathwayBrowser/#/R-PFA-156682 PLK1 phosphorylates NUDC IEA Plasmodium falciparum 456216 R-PFA-163215 https://reactome.org/PathwayBrowser/#/R-PFA-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Plasmodium falciparum 456216 R-PFA-1675773 https://reactome.org/PathwayBrowser/#/R-PFA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Plasmodium falciparum 456216 R-PFA-1675776 https://reactome.org/PathwayBrowser/#/R-PFA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Plasmodium falciparum 456216 R-PFA-1675810 https://reactome.org/PathwayBrowser/#/R-PFA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Plasmodium falciparum 456216 R-PFA-1675883 https://reactome.org/PathwayBrowser/#/R-PFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Plasmodium falciparum 456216 R-PFA-1675939 https://reactome.org/PathwayBrowser/#/R-PFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Plasmodium falciparum 456216 R-PFA-1675961 https://reactome.org/PathwayBrowser/#/R-PFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Plasmodium falciparum 456216 R-PFA-1676024 https://reactome.org/PathwayBrowser/#/R-PFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Plasmodium falciparum 456216 R-PFA-1676082 https://reactome.org/PathwayBrowser/#/R-PFA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Plasmodium falciparum 456216 R-PFA-1676134 https://reactome.org/PathwayBrowser/#/R-PFA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Plasmodium falciparum 456216 R-PFA-1676145 https://reactome.org/PathwayBrowser/#/R-PFA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Plasmodium falciparum 456216 R-PFA-174394 https://reactome.org/PathwayBrowser/#/R-PFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Plasmodium falciparum 456216 R-PFA-1855153 https://reactome.org/PathwayBrowser/#/R-PFA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Plasmodium falciparum 456216 R-PFA-1855157 https://reactome.org/PathwayBrowser/#/R-PFA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 456216 R-PFA-1855158 https://reactome.org/PathwayBrowser/#/R-PFA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 456216 R-PFA-1855181 https://reactome.org/PathwayBrowser/#/R-PFA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 456216 R-PFA-1855182 https://reactome.org/PathwayBrowser/#/R-PFA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Plasmodium falciparum 456216 R-PFA-1855185 https://reactome.org/PathwayBrowser/#/R-PFA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 456216 R-PFA-1855193 https://reactome.org/PathwayBrowser/#/R-PFA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 456216 R-PFA-1855194 https://reactome.org/PathwayBrowser/#/R-PFA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 456216 R-PFA-1855206 https://reactome.org/PathwayBrowser/#/R-PFA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 456216 R-PFA-1855207 https://reactome.org/PathwayBrowser/#/R-PFA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 456216 R-PFA-1855216 https://reactome.org/PathwayBrowser/#/R-PFA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Plasmodium falciparum 456216 R-PFA-1855223 https://reactome.org/PathwayBrowser/#/R-PFA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 456216 R-PFA-1855224 https://reactome.org/PathwayBrowser/#/R-PFA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 456216 R-PFA-1855227 https://reactome.org/PathwayBrowser/#/R-PFA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 456216 R-PFA-1855228 https://reactome.org/PathwayBrowser/#/R-PFA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 456216 R-PFA-1855230 https://reactome.org/PathwayBrowser/#/R-PFA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 456216 R-PFA-1855233 https://reactome.org/PathwayBrowser/#/R-PFA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Plasmodium falciparum 456216 R-PFA-193362 https://reactome.org/PathwayBrowser/#/R-PFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Plasmodium falciparum 456216 R-PFA-196964 https://reactome.org/PathwayBrowser/#/R-PFA-196964 RFK:Mg2+ phosphorylates RIB IEA Plasmodium falciparum 456216 R-PFA-200555 https://reactome.org/PathwayBrowser/#/R-PFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Plasmodium falciparum 456216 R-PFA-200711 https://reactome.org/PathwayBrowser/#/R-PFA-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Plasmodium falciparum 456216 R-PFA-202111 https://reactome.org/PathwayBrowser/#/R-PFA-202111 AKT1 phosphorylates eNOS IEA Plasmodium falciparum 456216 R-PFA-2214351 https://reactome.org/PathwayBrowser/#/R-PFA-2214351 PLK1 phosphorylates GORASP1 IEA Plasmodium falciparum 456216 R-PFA-2294580 https://reactome.org/PathwayBrowser/#/R-PFA-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Plasmodium falciparum 456216 R-PFA-2529020 https://reactome.org/PathwayBrowser/#/R-PFA-2529020 CK2 phosphorylates condensin I subunits IEA Plasmodium falciparum 456216 R-PFA-265783 https://reactome.org/PathwayBrowser/#/R-PFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Plasmodium falciparum 456216 R-PFA-3371422 https://reactome.org/PathwayBrowser/#/R-PFA-3371422 ATP hydrolysis by HSP70 IEA Plasmodium falciparum 456216 R-PFA-3371503 https://reactome.org/PathwayBrowser/#/R-PFA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Plasmodium falciparum 456216 R-PFA-383190 https://reactome.org/PathwayBrowser/#/R-PFA-383190 HCO3- transport through ion channel IEA Plasmodium falciparum 456216 R-PFA-426240 https://reactome.org/PathwayBrowser/#/R-PFA-426240 DAG kinase produces phosphatidic acid from DAG IEA Plasmodium falciparum 456216 R-PFA-429157 https://reactome.org/PathwayBrowser/#/R-PFA-429157 ABCC4 accumulation of dense granule contents IEA Plasmodium falciparum 456216 R-PFA-429714 https://reactome.org/PathwayBrowser/#/R-PFA-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Plasmodium falciparum 456216 R-PFA-4332358 https://reactome.org/PathwayBrowser/#/R-PFA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Plasmodium falciparum 456216 R-PFA-4332363 https://reactome.org/PathwayBrowser/#/R-PFA-4332363 Autophosphorylation and activation of CAMK2 IEA Plasmodium falciparum 456216 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 456216 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 456216 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 456216 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 456216 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 456216 R-PFA-504054 https://reactome.org/PathwayBrowser/#/R-PFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Plasmodium falciparum 456216 R-PFA-5251959 https://reactome.org/PathwayBrowser/#/R-PFA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Plasmodium falciparum 456216 R-PFA-5251989 https://reactome.org/PathwayBrowser/#/R-PFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Plasmodium falciparum 456216 R-PFA-5252079 https://reactome.org/PathwayBrowser/#/R-PFA-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Plasmodium falciparum 456216 R-PFA-5358525 https://reactome.org/PathwayBrowser/#/R-PFA-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Plasmodium falciparum 456216 R-PFA-5358912 https://reactome.org/PathwayBrowser/#/R-PFA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Plasmodium falciparum 456216 R-PFA-5444516 https://reactome.org/PathwayBrowser/#/R-PFA-5444516 Formation of MSH2:MSH6 Complex IEA Plasmodium falciparum 456216 R-PFA-5618085 https://reactome.org/PathwayBrowser/#/R-PFA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Plasmodium falciparum 456216 R-PFA-5618098 https://reactome.org/PathwayBrowser/#/R-PFA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Plasmodium falciparum 456216 R-PFA-5618105 https://reactome.org/PathwayBrowser/#/R-PFA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Plasmodium falciparum 456216 R-PFA-5618107 https://reactome.org/PathwayBrowser/#/R-PFA-5618107 ATP binding to HSP90 triggers conformation change IEA Plasmodium falciparum 456216 R-PFA-5618110 https://reactome.org/PathwayBrowser/#/R-PFA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Plasmodium falciparum 456216 R-PFA-5672948 https://reactome.org/PathwayBrowser/#/R-PFA-5672948 MARK3 phosphorylates KSR1 IEA Plasmodium falciparum 456216 R-PFA-5675194 https://reactome.org/PathwayBrowser/#/R-PFA-5675194 Activated MAPK phosphorylates RAF1 IEA Plasmodium falciparum 456216 R-PFA-5675198 https://reactome.org/PathwayBrowser/#/R-PFA-5675198 Activated MAPKs phosphorylate BRAF IEA Plasmodium falciparum 456216 R-PFA-5678706 https://reactome.org/PathwayBrowser/#/R-PFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Plasmodium falciparum 456216 R-PFA-5678863 https://reactome.org/PathwayBrowser/#/R-PFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Plasmodium falciparum 456216 R-PFA-5682285 https://reactome.org/PathwayBrowser/#/R-PFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Plasmodium falciparum 456216 R-PFA-5683714 https://reactome.org/PathwayBrowser/#/R-PFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Plasmodium falciparum 456216 R-PFA-5683792 https://reactome.org/PathwayBrowser/#/R-PFA-5683792 p-T68-CHEK2 autophosphorylates IEA Plasmodium falciparum 456216 R-PFA-5687094 https://reactome.org/PathwayBrowser/#/R-PFA-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Plasmodium falciparum 456216 R-PFA-5690250 https://reactome.org/PathwayBrowser/#/R-PFA-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Plasmodium falciparum 456216 R-PFA-5690996 https://reactome.org/PathwayBrowser/#/R-PFA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Plasmodium falciparum 456216 R-PFA-5692462 https://reactome.org/PathwayBrowser/#/R-PFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Plasmodium falciparum 456216 R-PFA-5692480 https://reactome.org/PathwayBrowser/#/R-PFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Plasmodium falciparum 456216 R-PFA-5693549 https://reactome.org/PathwayBrowser/#/R-PFA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Plasmodium falciparum 456216 R-PFA-5696839 https://reactome.org/PathwayBrowser/#/R-PFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Plasmodium falciparum 456216 R-PFA-6788798 https://reactome.org/PathwayBrowser/#/R-PFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 456216 R-PFA-6788810 https://reactome.org/PathwayBrowser/#/R-PFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 456216 R-PFA-6798174 https://reactome.org/PathwayBrowser/#/R-PFA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Plasmodium falciparum 456216 R-PFA-6801342 https://reactome.org/PathwayBrowser/#/R-PFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Plasmodium falciparum 456216 R-PFA-6801456 https://reactome.org/PathwayBrowser/#/R-PFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Plasmodium falciparum 456216 R-PFA-6806877 https://reactome.org/PathwayBrowser/#/R-PFA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Plasmodium falciparum 456216 R-PFA-6806967 https://reactome.org/PathwayBrowser/#/R-PFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Plasmodium falciparum 456216 R-PFA-6807868 https://reactome.org/PathwayBrowser/#/R-PFA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Plasmodium falciparum 456216 R-PFA-6811522 https://reactome.org/PathwayBrowser/#/R-PFA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Plasmodium falciparum 456216 R-PFA-6814120 https://reactome.org/PathwayBrowser/#/R-PFA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Plasmodium falciparum 456216 R-PFA-6814124 https://reactome.org/PathwayBrowser/#/R-PFA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Plasmodium falciparum 456216 R-PFA-69063 https://reactome.org/PathwayBrowser/#/R-PFA-69063 Loading of PCNA - Sliding Clamp Formation IEA Plasmodium falciparum 456216 R-PFA-70420 https://reactome.org/PathwayBrowser/#/R-PFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Plasmodium falciparum 456216 R-PFA-70486 https://reactome.org/PathwayBrowser/#/R-PFA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Plasmodium falciparum 456216 R-PFA-70997 https://reactome.org/PathwayBrowser/#/R-PFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Plasmodium falciparum 456216 R-PFA-71401 https://reactome.org/PathwayBrowser/#/R-PFA-71401 OGDH dimer decarboxylates 2-OG IEA Plasmodium falciparum 456216 R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 456216 R-PFA-71850 https://reactome.org/PathwayBrowser/#/R-PFA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Plasmodium falciparum 456216 R-PFA-72621 https://reactome.org/PathwayBrowser/#/R-PFA-72621 Ribosomal scanning IEA Plasmodium falciparum 456216 R-PFA-72647 https://reactome.org/PathwayBrowser/#/R-PFA-72647 Cap-bound mRNA is activated by helicases IEA Plasmodium falciparum 456216 R-PFA-73548 https://reactome.org/PathwayBrowser/#/R-PFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Plasmodium falciparum 456216 R-PFA-73577 https://reactome.org/PathwayBrowser/#/R-PFA-73577 CAD hexamer transforms L-Gln to CAP IEA Plasmodium falciparum 456216 R-PFA-73635 https://reactome.org/PathwayBrowser/#/R-PFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Plasmodium falciparum 456216 R-PFA-73647 https://reactome.org/PathwayBrowser/#/R-PFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Plasmodium falciparum 456216 R-PFA-73788 https://reactome.org/PathwayBrowser/#/R-PFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Plasmodium falciparum 456216 R-PFA-75125 https://reactome.org/PathwayBrowser/#/R-PFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Plasmodium falciparum 456216 R-PFA-75126 https://reactome.org/PathwayBrowser/#/R-PFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Plasmodium falciparum 456216 R-PFA-75851 https://reactome.org/PathwayBrowser/#/R-PFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 456216 R-PFA-75887 https://reactome.org/PathwayBrowser/#/R-PFA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Plasmodium falciparum 456216 R-PFA-77071 https://reactome.org/PathwayBrowser/#/R-PFA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Plasmodium falciparum 456216 R-PFA-8848053 https://reactome.org/PathwayBrowser/#/R-PFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Plasmodium falciparum 456216 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 456216 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 456216 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 456216 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 456216 R-PFA-8865774 https://reactome.org/PathwayBrowser/#/R-PFA-8865774 TTLLs polyglutamylate tubulin IEA Plasmodium falciparum 456216 R-PFA-8868066 https://reactome.org/PathwayBrowser/#/R-PFA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Plasmodium falciparum 456216 R-PFA-8876889 https://reactome.org/PathwayBrowser/#/R-PFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 456216 R-PFA-8955030 https://reactome.org/PathwayBrowser/#/R-PFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Plasmodium falciparum 456216 R-PFA-9012319 https://reactome.org/PathwayBrowser/#/R-PFA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Plasmodium falciparum 456216 R-PFA-917841 https://reactome.org/PathwayBrowser/#/R-PFA-917841 Acidification of Tf:TfR1 containing endosome IEA Plasmodium falciparum 456216 R-PFA-917979 https://reactome.org/PathwayBrowser/#/R-PFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Plasmodium falciparum 456216 R-PFA-927889 https://reactome.org/PathwayBrowser/#/R-PFA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Plasmodium falciparum 456216 R-PFA-936883 https://reactome.org/PathwayBrowser/#/R-PFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Plasmodium falciparum 456216 R-PFA-936895 https://reactome.org/PathwayBrowser/#/R-PFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Plasmodium falciparum 456216 R-PFA-939763 https://reactome.org/PathwayBrowser/#/R-PFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Plasmodium falciparum 456216 R-PFA-947591 https://reactome.org/PathwayBrowser/#/R-PFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Plasmodium falciparum 456216 R-PFA-9606884 https://reactome.org/PathwayBrowser/#/R-PFA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Plasmodium falciparum 456216 R-PFA-964958 https://reactome.org/PathwayBrowser/#/R-PFA-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Plasmodium falciparum 456216 R-PFA-964962 https://reactome.org/PathwayBrowser/#/R-PFA-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Plasmodium falciparum 456216 R-PFA-964970 https://reactome.org/PathwayBrowser/#/R-PFA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Plasmodium falciparum 456216 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 456216 R-PFA-9661417 https://reactome.org/PathwayBrowser/#/R-PFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Plasmodium falciparum 456216 R-PFA-9748949 https://reactome.org/PathwayBrowser/#/R-PFA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Plasmodium falciparum 456216 R-PFA-9748963 https://reactome.org/PathwayBrowser/#/R-PFA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Plasmodium falciparum 456216 R-PFA-9748969 https://reactome.org/PathwayBrowser/#/R-PFA-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Plasmodium falciparum 456216 R-PFA-9748999 https://reactome.org/PathwayBrowser/#/R-PFA-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Plasmodium falciparum 456216 R-PFA-9750546 https://reactome.org/PathwayBrowser/#/R-PFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Plasmodium falciparum 456216 R-PFA-9753278 https://reactome.org/PathwayBrowser/#/R-PFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 456216 R-PFA-9753283 https://reactome.org/PathwayBrowser/#/R-PFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 456216 R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 456216 R-PFA-9755013 https://reactome.org/PathwayBrowser/#/R-PFA-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Plasmodium falciparum 456216 R-PFA-9759454 https://reactome.org/PathwayBrowser/#/R-PFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Plasmodium falciparum 456216 R-PFA-9759461 https://reactome.org/PathwayBrowser/#/R-PFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Plasmodium falciparum 456216 R-PFA-9794120 https://reactome.org/PathwayBrowser/#/R-PFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Plasmodium falciparum 456216 R-PFA-9794572 https://reactome.org/PathwayBrowser/#/R-PFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Plasmodium falciparum 456216 R-PFA-9837333 https://reactome.org/PathwayBrowser/#/R-PFA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Plasmodium falciparum 456216 R-PFA-9837337 https://reactome.org/PathwayBrowser/#/R-PFA-9837337 DCAKD phosphorylates DP-CoA IEA Plasmodium falciparum 456216 R-PFA-9839105 https://reactome.org/PathwayBrowser/#/R-PFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Plasmodium falciparum 456216 R-PFA-9843721 https://reactome.org/PathwayBrowser/#/R-PFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Plasmodium falciparum 456216 R-RNO-1008248 https://reactome.org/PathwayBrowser/#/R-RNO-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Rattus norvegicus 456216 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 456216 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 456216 R-RNO-109415 https://reactome.org/PathwayBrowser/#/R-RNO-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Rattus norvegicus 456216 R-RNO-109624 https://reactome.org/PathwayBrowser/#/R-RNO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Rattus norvegicus 456216 R-RNO-109671 https://reactome.org/PathwayBrowser/#/R-RNO-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Rattus norvegicus 456216 R-RNO-109699 https://reactome.org/PathwayBrowser/#/R-RNO-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-109702 https://reactome.org/PathwayBrowser/#/R-RNO-109702 PDPK1 phosphorylates AKT2 IEA Rattus norvegicus 456216 R-RNO-109759 https://reactome.org/PathwayBrowser/#/R-RNO-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Rattus norvegicus 456216 R-RNO-109822 https://reactome.org/PathwayBrowser/#/R-RNO-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Rattus norvegicus 456216 R-RNO-109823 https://reactome.org/PathwayBrowser/#/R-RNO-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Rattus norvegicus 456216 R-RNO-109860 https://reactome.org/PathwayBrowser/#/R-RNO-109860 MAP2K1 phosphorylates MAPK3 IEA Rattus norvegicus 456216 R-RNO-109862 https://reactome.org/PathwayBrowser/#/R-RNO-109862 MAP2K2 phosphorylates MAPK1 IEA Rattus norvegicus 456216 R-RNO-109903 https://reactome.org/PathwayBrowser/#/R-RNO-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Rattus norvegicus 456216 R-RNO-110133 https://reactome.org/PathwayBrowser/#/R-RNO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Rattus norvegicus 456216 R-RNO-110137 https://reactome.org/PathwayBrowser/#/R-RNO-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Rattus norvegicus 456216 R-RNO-110138 https://reactome.org/PathwayBrowser/#/R-RNO-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 456216 R-RNO-110141 https://reactome.org/PathwayBrowser/#/R-RNO-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Rattus norvegicus 456216 R-RNO-110144 https://reactome.org/PathwayBrowser/#/R-RNO-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Rattus norvegicus 456216 R-RNO-110145 https://reactome.org/PathwayBrowser/#/R-RNO-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Rattus norvegicus 456216 R-RNO-1112510 https://reactome.org/PathwayBrowser/#/R-RNO-1112510 IL6ST is tyrosine phosphorylated IEA Rattus norvegicus 456216 R-RNO-1112514 https://reactome.org/PathwayBrowser/#/R-RNO-1112514 JAK activation IEA Rattus norvegicus 456216 R-RNO-1112602 https://reactome.org/PathwayBrowser/#/R-RNO-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Rattus norvegicus 456216 R-RNO-1112703 https://reactome.org/PathwayBrowser/#/R-RNO-1112703 PTPN11 is phosphorylated IEA Rattus norvegicus 456216 R-RNO-1112727 https://reactome.org/PathwayBrowser/#/R-RNO-1112727 Serine phosphorylation of STATs IEA Rattus norvegicus 456216 R-RNO-111898 https://reactome.org/PathwayBrowser/#/R-RNO-111898 Phosphorylation of cPLA2 by ERK-2 IEA Rattus norvegicus 456216 R-RNO-111915 https://reactome.org/PathwayBrowser/#/R-RNO-111915 CAMK4 autophosphorylates IEA Rattus norvegicus 456216 R-RNO-111970 https://reactome.org/PathwayBrowser/#/R-RNO-111970 PKC phosphorylates GRK2 IEA Rattus norvegicus 456216 R-RNO-112342 https://reactome.org/PathwayBrowser/#/R-RNO-112342 Inactivation of MAP2K1 by CDK1 IEA Rattus norvegicus 456216 R-RNO-112381 https://reactome.org/PathwayBrowser/#/R-RNO-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Rattus norvegicus 456216 R-RNO-114252 https://reactome.org/PathwayBrowser/#/R-RNO-114252 Cleavage of Procaspase-3 by the apoptosome IEA Rattus norvegicus 456216 R-RNO-114254 https://reactome.org/PathwayBrowser/#/R-RNO-114254 CYCS binds to APAF1 IEA Rattus norvegicus 456216 R-RNO-114259 https://reactome.org/PathwayBrowser/#/R-RNO-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Rattus norvegicus 456216 R-RNO-114261 https://reactome.org/PathwayBrowser/#/R-RNO-114261 Cleavage of Procaspase-7 by the apoptosome IEA Rattus norvegicus 456216 R-RNO-114600 https://reactome.org/PathwayBrowser/#/R-RNO-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Rattus norvegicus 456216 R-RNO-114683 https://reactome.org/PathwayBrowser/#/R-RNO-114683 Phosphorylation of Platelet Sec-1 IEA Rattus norvegicus 456216 R-RNO-114684 https://reactome.org/PathwayBrowser/#/R-RNO-114684 Phosphorylation of Syntaxin-4 IEA Rattus norvegicus 456216 R-RNO-1168459 https://reactome.org/PathwayBrowser/#/R-RNO-1168459 Lyn activates ERK IEA Rattus norvegicus 456216 R-RNO-1168635 https://reactome.org/PathwayBrowser/#/R-RNO-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Rattus norvegicus 456216 R-RNO-1168638 https://reactome.org/PathwayBrowser/#/R-RNO-1168638 Activated IKK phosphorylates I-kappaB IEA Rattus norvegicus 456216 R-RNO-1168854 https://reactome.org/PathwayBrowser/#/R-RNO-1168854 JAK2 phosphorylation of Irs-1/2 TAS Rattus norvegicus 456216 R-RNO-1181149 https://reactome.org/PathwayBrowser/#/R-RNO-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Rattus norvegicus 456216 R-RNO-1226094 https://reactome.org/PathwayBrowser/#/R-RNO-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Rattus norvegicus 456216 R-RNO-1226095 https://reactome.org/PathwayBrowser/#/R-RNO-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Rattus norvegicus 456216 R-RNO-1247935 https://reactome.org/PathwayBrowser/#/R-RNO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Rattus norvegicus 456216 R-RNO-1247960 https://reactome.org/PathwayBrowser/#/R-RNO-1247960 Activation of p38 MAPK IEA Rattus norvegicus 456216 R-RNO-1250195 https://reactome.org/PathwayBrowser/#/R-RNO-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Rattus norvegicus 456216 R-RNO-1250315 https://reactome.org/PathwayBrowser/#/R-RNO-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Rattus norvegicus 456216 R-RNO-1250348 https://reactome.org/PathwayBrowser/#/R-RNO-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Rattus norvegicus 456216 R-RNO-1250370 https://reactome.org/PathwayBrowser/#/R-RNO-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Rattus norvegicus 456216 R-RNO-1250462 https://reactome.org/PathwayBrowser/#/R-RNO-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Rattus norvegicus 456216 R-RNO-1295540 https://reactome.org/PathwayBrowser/#/R-RNO-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Rattus norvegicus 456216 R-RNO-1295609 https://reactome.org/PathwayBrowser/#/R-RNO-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Rattus norvegicus 456216 R-RNO-1306957 https://reactome.org/PathwayBrowser/#/R-RNO-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Rattus norvegicus 456216 R-RNO-1306979 https://reactome.org/PathwayBrowser/#/R-RNO-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Rattus norvegicus 456216 R-RNO-1307963 https://reactome.org/PathwayBrowser/#/R-RNO-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Rattus norvegicus 456216 R-RNO-1358791 https://reactome.org/PathwayBrowser/#/R-RNO-1358791 Phosphorylation of USP8 by P-AKT IEA Rattus norvegicus 456216 R-RNO-1362270 https://reactome.org/PathwayBrowser/#/R-RNO-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Rattus norvegicus 456216 R-RNO-1369028 https://reactome.org/PathwayBrowser/#/R-RNO-1369028 ABCAs mediate lipid efflux IEA Rattus norvegicus 456216 R-RNO-1369052 https://reactome.org/PathwayBrowser/#/R-RNO-1369052 ABCAs mediate lipid influx IEA Rattus norvegicus 456216 R-RNO-1369065 https://reactome.org/PathwayBrowser/#/R-RNO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Rattus norvegicus 456216 R-RNO-1369099 https://reactome.org/PathwayBrowser/#/R-RNO-1369099 Shp2 is phosphorylated TAS Rattus norvegicus 456216 R-RNO-1369121 https://reactome.org/PathwayBrowser/#/R-RNO-1369121 Tyrosine phosphorylation of Prlr TAS Rattus norvegicus 456216 R-RNO-1370505 https://reactome.org/PathwayBrowser/#/R-RNO-1370505 PRLR is phosphorylated at Ser-349 IEA Rattus norvegicus 456216 R-RNO-139908 https://reactome.org/PathwayBrowser/#/R-RNO-139908 Phosphorylation of DLC2 by MAPK8 IEA Rattus norvegicus 456216 R-RNO-139918 https://reactome.org/PathwayBrowser/#/R-RNO-139918 Phosphorylation of BIM by JNK IEA Rattus norvegicus 456216 R-RNO-1433418 https://reactome.org/PathwayBrowser/#/R-RNO-1433418 Phosphorylation of JAK2 IEA Rattus norvegicus 456216 R-RNO-1433454 https://reactome.org/PathwayBrowser/#/R-RNO-1433454 Phosphorylation of GAB2 by SFKs IEA Rattus norvegicus 456216 R-RNO-1433488 https://reactome.org/PathwayBrowser/#/R-RNO-1433488 Phosphorylation of SHP2 by SFKs IEA Rattus norvegicus 456216 R-RNO-1433506 https://reactome.org/PathwayBrowser/#/R-RNO-1433506 Phosphorylation of APS IEA Rattus norvegicus 456216 R-RNO-1433508 https://reactome.org/PathwayBrowser/#/R-RNO-1433508 PKC alpha interacts with and phosphorylates KIT IEA Rattus norvegicus 456216 R-RNO-1433514 https://reactome.org/PathwayBrowser/#/R-RNO-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Rattus norvegicus 456216 R-RNO-1433542 https://reactome.org/PathwayBrowser/#/R-RNO-1433542 Phosphorylation and activation of VAV1 IEA Rattus norvegicus 456216 R-RNO-1454916 https://reactome.org/PathwayBrowser/#/R-RNO-1454916 The ABCC family mediates organic anion transport IEA Rattus norvegicus 456216 R-RNO-1454928 https://reactome.org/PathwayBrowser/#/R-RNO-1454928 ABCG4 may mediate cholesterol efflux IEA Rattus norvegicus 456216 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-1470009 https://reactome.org/PathwayBrowser/#/R-RNO-1470009 Phosphorylation of STATs IEA Rattus norvegicus 456216 R-RNO-1472121 https://reactome.org/PathwayBrowser/#/R-RNO-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Rattus norvegicus 456216 R-RNO-1475422 https://reactome.org/PathwayBrowser/#/R-RNO-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Rattus norvegicus 456216 R-RNO-1483004 https://reactome.org/PathwayBrowser/#/R-RNO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Rattus norvegicus 456216 R-RNO-1483222 https://reactome.org/PathwayBrowser/#/R-RNO-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Rattus norvegicus 456216 R-RNO-1497853 https://reactome.org/PathwayBrowser/#/R-RNO-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Rattus norvegicus 456216 R-RNO-1524186 https://reactome.org/PathwayBrowser/#/R-RNO-1524186 Phosphorylation of PLCgamma by PDGFR IEA Rattus norvegicus 456216 R-RNO-1549526 https://reactome.org/PathwayBrowser/#/R-RNO-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Rattus norvegicus 456216 R-RNO-156673 https://reactome.org/PathwayBrowser/#/R-RNO-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Rattus norvegicus 456216 R-RNO-156678 https://reactome.org/PathwayBrowser/#/R-RNO-156678 Activation of Cdc25C IEA Rattus norvegicus 456216 R-RNO-156682 https://reactome.org/PathwayBrowser/#/R-RNO-156682 PLK1 phosphorylates NUDC IEA Rattus norvegicus 456216 R-RNO-156699 https://reactome.org/PathwayBrowser/#/R-RNO-156699 Inactivation of Wee1 kinase IEA Rattus norvegicus 456216 R-RNO-156723 https://reactome.org/PathwayBrowser/#/R-RNO-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Rattus norvegicus 456216 R-RNO-159101 https://reactome.org/PathwayBrowser/#/R-RNO-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Rattus norvegicus 456216 R-RNO-162657 https://reactome.org/PathwayBrowser/#/R-RNO-162657 Inactivation of Myt1 kinase IEA Rattus norvegicus 456216 R-RNO-163010 https://reactome.org/PathwayBrowser/#/R-RNO-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Rattus norvegicus 456216 R-RNO-163120 https://reactome.org/PathwayBrowser/#/R-RNO-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Rattus norvegicus 456216 R-RNO-163215 https://reactome.org/PathwayBrowser/#/R-RNO-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Rattus norvegicus 456216 R-RNO-1632857 https://reactome.org/PathwayBrowser/#/R-RNO-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Rattus norvegicus 456216 R-RNO-163472 https://reactome.org/PathwayBrowser/#/R-RNO-163472 hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP TAS Rattus norvegicus 456216 R-RNO-163601 https://reactome.org/PathwayBrowser/#/R-RNO-163601 perilipin + 3 ATP -> phosphorylated perilipin + 3 ADP TAS Rattus norvegicus 456216 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus 456216 R-RNO-1638845 https://reactome.org/PathwayBrowser/#/R-RNO-1638845 CERK phosphorylates CERA to form C1P IEA Rattus norvegicus 456216 R-RNO-164832 https://reactome.org/PathwayBrowser/#/R-RNO-164832 ATPase synthesizes ATP IEA Rattus norvegicus 456216 R-RNO-164840 https://reactome.org/PathwayBrowser/#/R-RNO-164840 ADP and Pi bind to ATPase IEA Rattus norvegicus 456216 R-RNO-165162 https://reactome.org/PathwayBrowser/#/R-RNO-165162 Phosphorylation of TSC2 by PKB IEA Rattus norvegicus 456216 R-RNO-165182 https://reactome.org/PathwayBrowser/#/R-RNO-165182 Phosphorylation of complexed TSC2 by PKB IEA Rattus norvegicus 456216 R-RNO-165692 https://reactome.org/PathwayBrowser/#/R-RNO-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Rattus norvegicus 456216 R-RNO-165718 https://reactome.org/PathwayBrowser/#/R-RNO-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Rattus norvegicus 456216 R-RNO-165726 https://reactome.org/PathwayBrowser/#/R-RNO-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Rattus norvegicus 456216 R-RNO-165758 https://reactome.org/PathwayBrowser/#/R-RNO-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Rattus norvegicus 456216 R-RNO-165766 https://reactome.org/PathwayBrowser/#/R-RNO-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Rattus norvegicus 456216 R-RNO-166245 https://reactome.org/PathwayBrowser/#/R-RNO-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Rattus norvegicus 456216 R-RNO-1671699 https://reactome.org/PathwayBrowser/#/R-RNO-1671699 Prlr-bound Stat5 is phosphorylated TAS Rattus norvegicus 456216 R-RNO-1675773 https://reactome.org/PathwayBrowser/#/R-RNO-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Rattus norvegicus 456216 R-RNO-1675776 https://reactome.org/PathwayBrowser/#/R-RNO-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Rattus norvegicus 456216 R-RNO-1675780 https://reactome.org/PathwayBrowser/#/R-RNO-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Rattus norvegicus 456216 R-RNO-1675810 https://reactome.org/PathwayBrowser/#/R-RNO-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Rattus norvegicus 456216 R-RNO-1675813 https://reactome.org/PathwayBrowser/#/R-RNO-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Rattus norvegicus 456216 R-RNO-1675883 https://reactome.org/PathwayBrowser/#/R-RNO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Rattus norvegicus 456216 R-RNO-1675928 https://reactome.org/PathwayBrowser/#/R-RNO-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Rattus norvegicus 456216 R-RNO-1675939 https://reactome.org/PathwayBrowser/#/R-RNO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Rattus norvegicus 456216 R-RNO-1675961 https://reactome.org/PathwayBrowser/#/R-RNO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Rattus norvegicus 456216 R-RNO-1675974 https://reactome.org/PathwayBrowser/#/R-RNO-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Rattus norvegicus 456216 R-RNO-1676024 https://reactome.org/PathwayBrowser/#/R-RNO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Rattus norvegicus 456216 R-RNO-1676048 https://reactome.org/PathwayBrowser/#/R-RNO-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Rattus norvegicus 456216 R-RNO-1676082 https://reactome.org/PathwayBrowser/#/R-RNO-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Rattus norvegicus 456216 R-RNO-1676109 https://reactome.org/PathwayBrowser/#/R-RNO-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Rattus norvegicus 456216 R-RNO-1676134 https://reactome.org/PathwayBrowser/#/R-RNO-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Rattus norvegicus 456216 R-RNO-1676145 https://reactome.org/PathwayBrowser/#/R-RNO-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Rattus norvegicus 456216 R-RNO-1676185 https://reactome.org/PathwayBrowser/#/R-RNO-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Rattus norvegicus 456216 R-RNO-1676206 https://reactome.org/PathwayBrowser/#/R-RNO-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Rattus norvegicus 456216 R-RNO-1678944 https://reactome.org/PathwayBrowser/#/R-RNO-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Rattus norvegicus 456216 R-RNO-168053 https://reactome.org/PathwayBrowser/#/R-RNO-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Rattus norvegicus 456216 R-RNO-168136 https://reactome.org/PathwayBrowser/#/R-RNO-168136 Activated JNKs phosphorylate c-JUN IEA Rattus norvegicus 456216 R-RNO-168140 https://reactome.org/PathwayBrowser/#/R-RNO-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Rattus norvegicus 456216 R-RNO-168162 https://reactome.org/PathwayBrowser/#/R-RNO-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Rattus norvegicus 456216 R-RNO-169905 https://reactome.org/PathwayBrowser/#/R-RNO-169905 ARMS is phosphorylated by active TrkA receptor IEA Rattus norvegicus 456216 R-RNO-170026 https://reactome.org/PathwayBrowser/#/R-RNO-170026 Protons are translocated from the intermembrane space to the matrix IEA Rattus norvegicus 456216 R-RNO-170055 https://reactome.org/PathwayBrowser/#/R-RNO-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Rattus norvegicus 456216 R-RNO-170070 https://reactome.org/PathwayBrowser/#/R-RNO-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Rattus norvegicus 456216 R-RNO-170076 https://reactome.org/PathwayBrowser/#/R-RNO-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Rattus norvegicus 456216 R-RNO-170087 https://reactome.org/PathwayBrowser/#/R-RNO-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Rattus norvegicus 456216 R-RNO-170126 https://reactome.org/PathwayBrowser/#/R-RNO-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Rattus norvegicus 456216 R-RNO-170843 https://reactome.org/PathwayBrowser/#/R-RNO-170843 TGFBR2 phosphorylates TGFBR1 IEA Rattus norvegicus 456216 R-RNO-170868 https://reactome.org/PathwayBrowser/#/R-RNO-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Rattus norvegicus 456216 R-RNO-170977 https://reactome.org/PathwayBrowser/#/R-RNO-170977 FRS2 is phosphorylated by active TrkA receptor IEA Rattus norvegicus 456216 R-RNO-174079 https://reactome.org/PathwayBrowser/#/R-RNO-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Rattus norvegicus 456216 R-RNO-174122 https://reactome.org/PathwayBrowser/#/R-RNO-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Rattus norvegicus 456216 R-RNO-174164 https://reactome.org/PathwayBrowser/#/R-RNO-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Rattus norvegicus 456216 R-RNO-174174 https://reactome.org/PathwayBrowser/#/R-RNO-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Rattus norvegicus 456216 R-RNO-174251 https://reactome.org/PathwayBrowser/#/R-RNO-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Rattus norvegicus 456216 R-RNO-174367 https://reactome.org/PathwayBrowser/#/R-RNO-174367 GCL ligates L-Glu to L-Cys IEA Rattus norvegicus 456216 R-RNO-174389 https://reactome.org/PathwayBrowser/#/R-RNO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Rattus norvegicus 456216 R-RNO-174394 https://reactome.org/PathwayBrowser/#/R-RNO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Rattus norvegicus 456216 R-RNO-174438 https://reactome.org/PathwayBrowser/#/R-RNO-174438 Formation of the Flap Intermediate on the C-strand IEA Rattus norvegicus 456216 R-RNO-174439 https://reactome.org/PathwayBrowser/#/R-RNO-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Rattus norvegicus 456216 R-RNO-176116 https://reactome.org/PathwayBrowser/#/R-RNO-176116 Recruitment and activation of Chk1 IEA Rattus norvegicus 456216 R-RNO-176298 https://reactome.org/PathwayBrowser/#/R-RNO-176298 Activation of claspin IEA Rattus norvegicus 456216 R-RNO-177275 https://reactome.org/PathwayBrowser/#/R-RNO-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Rattus norvegicus 456216 R-RNO-177284 https://reactome.org/PathwayBrowser/#/R-RNO-177284 PKA phosphorylates PDE4B IEA Rattus norvegicus 456216 R-RNO-177930 https://reactome.org/PathwayBrowser/#/R-RNO-177930 GAB1 phosphorylation by EGFR kinase IEA Rattus norvegicus 456216 R-RNO-177933 https://reactome.org/PathwayBrowser/#/R-RNO-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Rattus norvegicus 456216 R-RNO-177934 https://reactome.org/PathwayBrowser/#/R-RNO-177934 EGFR autophosphorylation IEA Rattus norvegicus 456216 R-RNO-177937 https://reactome.org/PathwayBrowser/#/R-RNO-177937 Phosphorylation of EGFR by SRC kinase IEA Rattus norvegicus 456216 R-RNO-177939 https://reactome.org/PathwayBrowser/#/R-RNO-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Rattus norvegicus 456216 R-RNO-181812 https://reactome.org/PathwayBrowser/#/R-RNO-181812 Trk receptor autophosphorylates TAS Rattus norvegicus 456216 R-RNO-182072 https://reactome.org/PathwayBrowser/#/R-RNO-182072 Active Trk phosphorylates Plcg1 TAS Rattus norvegicus 456216 R-RNO-182969 https://reactome.org/PathwayBrowser/#/R-RNO-182969 Phosphorylation of CBL (EGFR:CBL) IEA Rattus norvegicus 456216 R-RNO-183058 https://reactome.org/PathwayBrowser/#/R-RNO-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Rattus norvegicus 456216 R-RNO-1855153 https://reactome.org/PathwayBrowser/#/R-RNO-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855157 https://reactome.org/PathwayBrowser/#/R-RNO-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Rattus norvegicus 456216 R-RNO-1855158 https://reactome.org/PathwayBrowser/#/R-RNO-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855162 https://reactome.org/PathwayBrowser/#/R-RNO-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855169 https://reactome.org/PathwayBrowser/#/R-RNO-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855172 https://reactome.org/PathwayBrowser/#/R-RNO-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855176 https://reactome.org/PathwayBrowser/#/R-RNO-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Rattus norvegicus 456216 R-RNO-1855179 https://reactome.org/PathwayBrowser/#/R-RNO-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855181 https://reactome.org/PathwayBrowser/#/R-RNO-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Rattus norvegicus 456216 R-RNO-1855182 https://reactome.org/PathwayBrowser/#/R-RNO-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855185 https://reactome.org/PathwayBrowser/#/R-RNO-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 456216 R-RNO-1855193 https://reactome.org/PathwayBrowser/#/R-RNO-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855194 https://reactome.org/PathwayBrowser/#/R-RNO-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855197 https://reactome.org/PathwayBrowser/#/R-RNO-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855206 https://reactome.org/PathwayBrowser/#/R-RNO-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 456216 R-RNO-1855207 https://reactome.org/PathwayBrowser/#/R-RNO-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Rattus norvegicus 456216 R-RNO-1855216 https://reactome.org/PathwayBrowser/#/R-RNO-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855223 https://reactome.org/PathwayBrowser/#/R-RNO-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855224 https://reactome.org/PathwayBrowser/#/R-RNO-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Rattus norvegicus 456216 R-RNO-1855227 https://reactome.org/PathwayBrowser/#/R-RNO-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Rattus norvegicus 456216 R-RNO-1855228 https://reactome.org/PathwayBrowser/#/R-RNO-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 456216 R-RNO-1855230 https://reactome.org/PathwayBrowser/#/R-RNO-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Rattus norvegicus 456216 R-RNO-1855233 https://reactome.org/PathwayBrowser/#/R-RNO-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Rattus norvegicus 456216 R-RNO-1861595 https://reactome.org/PathwayBrowser/#/R-RNO-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Rattus norvegicus 456216 R-RNO-186786 https://reactome.org/PathwayBrowser/#/R-RNO-186786 Autophosphorylation of PDGF beta receptors IEA Rattus norvegicus 456216 R-RNO-186800 https://reactome.org/PathwayBrowser/#/R-RNO-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-187520 https://reactome.org/PathwayBrowser/#/R-RNO-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Rattus norvegicus 456216 R-RNO-187682 https://reactome.org/PathwayBrowser/#/R-RNO-187682 Binding and activation of MAP kinase TAS Rattus norvegicus 456216 R-RNO-187688 https://reactome.org/PathwayBrowser/#/R-RNO-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Rattus norvegicus 456216 R-RNO-187916 https://reactome.org/PathwayBrowser/#/R-RNO-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Rattus norvegicus 456216 R-RNO-187948 https://reactome.org/PathwayBrowser/#/R-RNO-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Rattus norvegicus 456216 R-RNO-187949 https://reactome.org/PathwayBrowser/#/R-RNO-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Rattus norvegicus 456216 R-RNO-187959 https://reactome.org/PathwayBrowser/#/R-RNO-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Rattus norvegicus 456216 R-RNO-188350 https://reactome.org/PathwayBrowser/#/R-RNO-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Rattus norvegicus 456216 R-RNO-188390 https://reactome.org/PathwayBrowser/#/R-RNO-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Rattus norvegicus 456216 R-RNO-190326 https://reactome.org/PathwayBrowser/#/R-RNO-190326 Autocatalytic phosphorylation of FGFR4 IEA Rattus norvegicus 456216 R-RNO-190385 https://reactome.org/PathwayBrowser/#/R-RNO-190385 Autocatalytic phosphorylation of FGFR3b IEA Rattus norvegicus 456216 R-RNO-190388 https://reactome.org/PathwayBrowser/#/R-RNO-190388 Autocatalytic phosphorylation of FGFR3c IEA Rattus norvegicus 456216 R-RNO-190408 https://reactome.org/PathwayBrowser/#/R-RNO-190408 Autocatalytic phosphorylation of FGFR2b IEA Rattus norvegicus 456216 R-RNO-190413 https://reactome.org/PathwayBrowser/#/R-RNO-190413 Autocatalytic phosphorylation of FGFR2c IEA Rattus norvegicus 456216 R-RNO-190427 https://reactome.org/PathwayBrowser/#/R-RNO-190427 Autocatalytic phosphorylation of FGFR1b IEA Rattus norvegicus 456216 R-RNO-190429 https://reactome.org/PathwayBrowser/#/R-RNO-190429 Autocatalytic phosphorylation of FGFR1c IEA Rattus norvegicus 456216 R-RNO-191062 https://reactome.org/PathwayBrowser/#/R-RNO-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Rattus norvegicus 456216 R-RNO-191380 https://reactome.org/PathwayBrowser/#/R-RNO-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Rattus norvegicus 456216 R-RNO-191414 https://reactome.org/PathwayBrowser/#/R-RNO-191414 MVD decarboxylates MVA5PP to IPPP IEA Rattus norvegicus 456216 R-RNO-191422 https://reactome.org/PathwayBrowser/#/R-RNO-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Rattus norvegicus 456216 R-RNO-191636 https://reactome.org/PathwayBrowser/#/R-RNO-191636 Phosphorylation of Cx43 by c-src IEA Rattus norvegicus 456216 R-RNO-193362 https://reactome.org/PathwayBrowser/#/R-RNO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-193703 https://reactome.org/PathwayBrowser/#/R-RNO-193703 IKKbeta is activated IEA Rattus norvegicus 456216 R-RNO-193887 https://reactome.org/PathwayBrowser/#/R-RNO-193887 Irak is activated TAS Rattus norvegicus 456216 R-RNO-194153 https://reactome.org/PathwayBrowser/#/R-RNO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-195275 https://reactome.org/PathwayBrowser/#/R-RNO-195275 Phosphorylation of APC component of the destruction complex IEA Rattus norvegicus 456216 R-RNO-195283 https://reactome.org/PathwayBrowser/#/R-RNO-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Rattus norvegicus 456216 R-RNO-195287 https://reactome.org/PathwayBrowser/#/R-RNO-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Rattus norvegicus 456216 R-RNO-195300 https://reactome.org/PathwayBrowser/#/R-RNO-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Rattus norvegicus 456216 R-RNO-195318 https://reactome.org/PathwayBrowser/#/R-RNO-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Rattus norvegicus 456216 R-RNO-1963581 https://reactome.org/PathwayBrowser/#/R-RNO-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Rattus norvegicus 456216 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 456216 R-RNO-1963586 https://reactome.org/PathwayBrowser/#/R-RNO-1963586 SRC family kinases phosphorylate ERBB2 IEA Rattus norvegicus 456216 R-RNO-196773 https://reactome.org/PathwayBrowser/#/R-RNO-196773 COASY phosphorylates DP-CoA IEA Rattus norvegicus 456216 R-RNO-196857 https://reactome.org/PathwayBrowser/#/R-RNO-196857 PANK2 phosphorylates PanK IEA Rattus norvegicus 456216 R-RNO-196964 https://reactome.org/PathwayBrowser/#/R-RNO-196964 RFK:Mg2+ phosphorylates RIB IEA Rattus norvegicus 456216 R-RNO-197198 https://reactome.org/PathwayBrowser/#/R-RNO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 456216 R-RNO-197958 https://reactome.org/PathwayBrowser/#/R-RNO-197958 FPGS-2 transforms THF to THFPG IEA Rattus norvegicus 456216 R-RNO-198266 https://reactome.org/PathwayBrowser/#/R-RNO-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Rattus norvegicus 456216 R-RNO-198314 https://reactome.org/PathwayBrowser/#/R-RNO-198314 DAG stimulates protein kinase C-delta IEA Rattus norvegicus 456216 R-RNO-198599 https://reactome.org/PathwayBrowser/#/R-RNO-198599 AKT phosphorylates MDM2 IEA Rattus norvegicus 456216 R-RNO-198601 https://reactome.org/PathwayBrowser/#/R-RNO-198601 Akt1 phosphorylates GSK3 TAS Rattus norvegicus 456216 R-RNO-198609 https://reactome.org/PathwayBrowser/#/R-RNO-198609 AKT phosphorylates TSC2, inhibiting it IEA Rattus norvegicus 456216 R-RNO-198611 https://reactome.org/PathwayBrowser/#/R-RNO-198611 AKT phosphorylates IKKalpha IEA Rattus norvegicus 456216 R-RNO-198613 https://reactome.org/PathwayBrowser/#/R-RNO-198613 AKT phosphorylates p21Cip1 and p27Kip1 IEA Rattus norvegicus 456216 R-RNO-198621 https://reactome.org/PathwayBrowser/#/R-RNO-198621 AKT phosphorylates caspase-9 IEA Rattus norvegicus 456216 R-RNO-198640 https://reactome.org/PathwayBrowser/#/R-RNO-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Rattus norvegicus 456216 R-RNO-198669 https://reactome.org/PathwayBrowser/#/R-RNO-198669 p38MAPK phosphorylates MSK1 IEA Rattus norvegicus 456216 R-RNO-198717 https://reactome.org/PathwayBrowser/#/R-RNO-198717 STAT3 activation TAS Rattus norvegicus 456216 R-RNO-198739 https://reactome.org/PathwayBrowser/#/R-RNO-198739 ERK5 is activated TAS Rattus norvegicus 456216 R-RNO-198746 https://reactome.org/PathwayBrowser/#/R-RNO-198746 ERK1/2/5 activate RSK1/2/3 IEA Rattus norvegicus 456216 R-RNO-198756 https://reactome.org/PathwayBrowser/#/R-RNO-198756 ERK1/2 phosphorylates MSK1 IEA Rattus norvegicus 456216 R-RNO-199203 https://reactome.org/PathwayBrowser/#/R-RNO-199203 PANK1/3 phosphorylate PanK IEA Rattus norvegicus 456216 R-RNO-199298 https://reactome.org/PathwayBrowser/#/R-RNO-199298 AKT phosphorylates CREB1 IEA Rattus norvegicus 456216 R-RNO-199299 https://reactome.org/PathwayBrowser/#/R-RNO-199299 AKT phosphorylates FOXO transcription factors IEA Rattus norvegicus 456216 R-RNO-199839 https://reactome.org/PathwayBrowser/#/R-RNO-199839 AKT can phosphorylate RSK IEA Rattus norvegicus 456216 R-RNO-199863 https://reactome.org/PathwayBrowser/#/R-RNO-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Rattus norvegicus 456216 R-RNO-199895 https://reactome.org/PathwayBrowser/#/R-RNO-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Rattus norvegicus 456216 R-RNO-199910 https://reactome.org/PathwayBrowser/#/R-RNO-199910 MSK1 activates ATF1 IEA Rattus norvegicus 456216 R-RNO-199913 https://reactome.org/PathwayBrowser/#/R-RNO-199913 ERK5 activates the transcription factor MEF2 TAS Rattus norvegicus 456216 R-RNO-199917 https://reactome.org/PathwayBrowser/#/R-RNO-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Rattus norvegicus 456216 R-RNO-199935 https://reactome.org/PathwayBrowser/#/R-RNO-199935 MSK1 activates CREB IEA Rattus norvegicus 456216 R-RNO-200143 https://reactome.org/PathwayBrowser/#/R-RNO-200143 AKT phosphorylates AKT1S1 (PRAS40) IEA Rattus norvegicus 456216 R-RNO-200318 https://reactome.org/PathwayBrowser/#/R-RNO-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Rattus norvegicus 456216 R-RNO-200326 https://reactome.org/PathwayBrowser/#/R-RNO-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Rattus norvegicus 456216 R-RNO-200421 https://reactome.org/PathwayBrowser/#/R-RNO-200421 Activation of cytosolic AMPK by phosphorylation IEA Rattus norvegicus 456216 R-RNO-200423 https://reactome.org/PathwayBrowser/#/R-RNO-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Rattus norvegicus 456216 R-RNO-200555 https://reactome.org/PathwayBrowser/#/R-RNO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Rattus norvegicus 456216 R-RNO-200681 https://reactome.org/PathwayBrowser/#/R-RNO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Rattus norvegicus 456216 R-RNO-200682 https://reactome.org/PathwayBrowser/#/R-RNO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Rattus norvegicus 456216 R-RNO-200711 https://reactome.org/PathwayBrowser/#/R-RNO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Rattus norvegicus 456216 R-RNO-201443 https://reactome.org/PathwayBrowser/#/R-RNO-201443 Type II receptor phosphorylates type I receptor IEA Rattus norvegicus 456216 R-RNO-201476 https://reactome.org/PathwayBrowser/#/R-RNO-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Rattus norvegicus 456216 R-RNO-201510 https://reactome.org/PathwayBrowser/#/R-RNO-201510 PI3K synthesizes PIP3 downstream of ALK IEA Rattus norvegicus 456216 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 456216 R-RNO-201677 https://reactome.org/PathwayBrowser/#/R-RNO-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Rattus norvegicus 456216 R-RNO-201717 https://reactome.org/PathwayBrowser/#/R-RNO-201717 CSNK2-mediated phosphorylation of DVL IEA Rattus norvegicus 456216 R-RNO-202111 https://reactome.org/PathwayBrowser/#/R-RNO-202111 AKT1 phosphorylates eNOS IEA Rattus norvegicus 456216 R-RNO-202165 https://reactome.org/PathwayBrowser/#/R-RNO-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Rattus norvegicus 456216 R-RNO-202168 https://reactome.org/PathwayBrowser/#/R-RNO-202168 Phosphorylation of ZAP-70 by Lck IEA Rattus norvegicus 456216 R-RNO-202174 https://reactome.org/PathwayBrowser/#/R-RNO-202174 Activation of ZAP-70 IEA Rattus norvegicus 456216 R-RNO-202216 https://reactome.org/PathwayBrowser/#/R-RNO-202216 Phosphorylation of SLP-76 IEA Rattus norvegicus 456216 R-RNO-202222 https://reactome.org/PathwayBrowser/#/R-RNO-202222 Phosphorylation of PKC theta IEA Rattus norvegicus 456216 R-RNO-202233 https://reactome.org/PathwayBrowser/#/R-RNO-202233 Inactivation of Lck by Csk IEA Rattus norvegicus 456216 R-RNO-202245 https://reactome.org/PathwayBrowser/#/R-RNO-202245 Phosphorylation of TBSMs in LAT IEA Rattus norvegicus 456216 R-RNO-202248 https://reactome.org/PathwayBrowser/#/R-RNO-202248 Phosphorylation of PLC-gamma1 IEA Rattus norvegicus 456216 R-RNO-202291 https://reactome.org/PathwayBrowser/#/R-RNO-202291 Activation of Lck IEA Rattus norvegicus 456216 R-RNO-202307 https://reactome.org/PathwayBrowser/#/R-RNO-202307 Change of PKC theta conformation IEA Rattus norvegicus 456216 R-RNO-202365 https://reactome.org/PathwayBrowser/#/R-RNO-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-202437 https://reactome.org/PathwayBrowser/#/R-RNO-202437 Phosphorylation of CARMA1 IEA Rattus norvegicus 456216 R-RNO-202459 https://reactome.org/PathwayBrowser/#/R-RNO-202459 Phosphorylation of Bcl10 IEA Rattus norvegicus 456216 R-RNO-202500 https://reactome.org/PathwayBrowser/#/R-RNO-202500 Activation of IKK complex IEA Rattus norvegicus 456216 R-RNO-202510 https://reactome.org/PathwayBrowser/#/R-RNO-202510 Activation of TAK1-TAB2 complex IEA Rattus norvegicus 456216 R-RNO-2028284 https://reactome.org/PathwayBrowser/#/R-RNO-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Rattus norvegicus 456216 R-RNO-2028555 https://reactome.org/PathwayBrowser/#/R-RNO-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Rattus norvegicus 456216 R-RNO-2028583 https://reactome.org/PathwayBrowser/#/R-RNO-2028583 Phosphorylation of YAP by LATS2 IEA Rattus norvegicus 456216 R-RNO-2028589 https://reactome.org/PathwayBrowser/#/R-RNO-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Rattus norvegicus 456216 R-RNO-2028591 https://reactome.org/PathwayBrowser/#/R-RNO-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Rattus norvegicus 456216 R-RNO-2028598 https://reactome.org/PathwayBrowser/#/R-RNO-2028598 Phosphorylation of YAP by LATS1 IEA Rattus norvegicus 456216 R-RNO-2028629 https://reactome.org/PathwayBrowser/#/R-RNO-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Rattus norvegicus 456216 R-RNO-2028635 https://reactome.org/PathwayBrowser/#/R-RNO-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Rattus norvegicus 456216 R-RNO-2028661 https://reactome.org/PathwayBrowser/#/R-RNO-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Rattus norvegicus 456216 R-RNO-2028670 https://reactome.org/PathwayBrowser/#/R-RNO-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Rattus norvegicus 456216 R-RNO-2028673 https://reactome.org/PathwayBrowser/#/R-RNO-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Rattus norvegicus 456216 R-RNO-2028675 https://reactome.org/PathwayBrowser/#/R-RNO-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Rattus norvegicus 456216 R-RNO-2028679 https://reactome.org/PathwayBrowser/#/R-RNO-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Rattus norvegicus 456216 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus 456216 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus 456216 R-RNO-2029454 https://reactome.org/PathwayBrowser/#/R-RNO-2029454 Autophosphorylation of PAK1 IEA Rattus norvegicus 456216 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus 456216 R-RNO-2029460 https://reactome.org/PathwayBrowser/#/R-RNO-2029460 PAK1 phosphorylates LIMK1 IEA Rattus norvegicus 456216 R-RNO-2029469 https://reactome.org/PathwayBrowser/#/R-RNO-2029469 p-ERK phosphorylates WAVEs and ABI IEA Rattus norvegicus 456216 R-RNO-2029473 https://reactome.org/PathwayBrowser/#/R-RNO-2029473 Branching and elongation of mother and daughter filaments IEA Rattus norvegicus 456216 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus 456216 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 456216 R-RNO-2046087 https://reactome.org/PathwayBrowser/#/R-RNO-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Rattus norvegicus 456216 R-RNO-2046093 https://reactome.org/PathwayBrowser/#/R-RNO-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Rattus norvegicus 456216 R-RNO-205027 https://reactome.org/PathwayBrowser/#/R-RNO-205027 Nrage activates Jnk1 TAS Rattus norvegicus 456216 R-RNO-205075 https://reactome.org/PathwayBrowser/#/R-RNO-205075 JNK phosphorylates BIM, BAD and other targets IEA Rattus norvegicus 456216 R-RNO-205136 https://reactome.org/PathwayBrowser/#/R-RNO-205136 GTP-bound RAC contributes to JNK activation IEA Rattus norvegicus 456216 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 456216 R-RNO-2054095 https://reactome.org/PathwayBrowser/#/R-RNO-2054095 Phosphorylation of syk TAS Rattus norvegicus 456216 R-RNO-2060328 https://reactome.org/PathwayBrowser/#/R-RNO-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Rattus norvegicus 456216 R-RNO-209087 https://reactome.org/PathwayBrowser/#/R-RNO-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Rattus norvegicus 456216 R-RNO-210291 https://reactome.org/PathwayBrowser/#/R-RNO-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Rattus norvegicus 456216 R-RNO-211164 https://reactome.org/PathwayBrowser/#/R-RNO-211164 AKT phosphorylates FOXO1A IEA Rattus norvegicus 456216 R-RNO-212710 https://reactome.org/PathwayBrowser/#/R-RNO-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Rattus norvegicus 456216 R-RNO-2130194 https://reactome.org/PathwayBrowser/#/R-RNO-2130194 ABL phosphorylates WAVEs IEA Rattus norvegicus 456216 R-RNO-2162084 https://reactome.org/PathwayBrowser/#/R-RNO-2162084 carbovir diphosphate + ATP => carbovir triphosphate + ADP TAS Rattus norvegicus 456216 R-RNO-216723 https://reactome.org/PathwayBrowser/#/R-RNO-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 456216 R-RNO-216757 https://reactome.org/PathwayBrowser/#/R-RNO-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 456216 R-RNO-2168079 https://reactome.org/PathwayBrowser/#/R-RNO-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Rattus norvegicus 456216 R-RNO-2176475 https://reactome.org/PathwayBrowser/#/R-RNO-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Rattus norvegicus 456216 R-RNO-2197690 https://reactome.org/PathwayBrowser/#/R-RNO-2197690 Detachment of WASP/WAVE IEA Rattus norvegicus 456216 R-RNO-2197698 https://reactome.org/PathwayBrowser/#/R-RNO-2197698 Src phosphorylate WASP,N-WASP IEA Rattus norvegicus 456216 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus 456216 R-RNO-2214351 https://reactome.org/PathwayBrowser/#/R-RNO-2214351 PLK1 phosphorylates GORASP1 IEA Rattus norvegicus 456216 R-RNO-2267372 https://reactome.org/PathwayBrowser/#/R-RNO-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Rattus norvegicus 456216 R-RNO-2294580 https://reactome.org/PathwayBrowser/#/R-RNO-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Rattus norvegicus 456216 R-RNO-2294600 https://reactome.org/PathwayBrowser/#/R-RNO-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Rattus norvegicus 456216 R-RNO-2316434 https://reactome.org/PathwayBrowser/#/R-RNO-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-2395412 https://reactome.org/PathwayBrowser/#/R-RNO-2395412 Phosphorylation of SYK IEA Rattus norvegicus 456216 R-RNO-2395801 https://reactome.org/PathwayBrowser/#/R-RNO-2395801 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus 456216 R-RNO-2396002 https://reactome.org/PathwayBrowser/#/R-RNO-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex IEA Rattus norvegicus 456216 R-RNO-2396007 https://reactome.org/PathwayBrowser/#/R-RNO-2396007 IRF3 is phosphorylated by TBK1 IEA Rattus norvegicus 456216 R-RNO-2396594 https://reactome.org/PathwayBrowser/#/R-RNO-2396594 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus 456216 R-RNO-2404193 https://reactome.org/PathwayBrowser/#/R-RNO-2404193 IGF1R phosphorylates SHC1 IEA Rattus norvegicus 456216 R-RNO-2404199 https://reactome.org/PathwayBrowser/#/R-RNO-2404199 IGF1,2:IGF1R autophosphorylates IEA Rattus norvegicus 456216 R-RNO-2422927 https://reactome.org/PathwayBrowser/#/R-RNO-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Rattus norvegicus 456216 R-RNO-2424480 https://reactome.org/PathwayBrowser/#/R-RNO-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-2424484 https://reactome.org/PathwayBrowser/#/R-RNO-2424484 Phosphorylation of BTK by p-SYK IEA Rattus norvegicus 456216 R-RNO-2424486 https://reactome.org/PathwayBrowser/#/R-RNO-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Rattus norvegicus 456216 R-RNO-2424487 https://reactome.org/PathwayBrowser/#/R-RNO-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Rattus norvegicus 456216 R-RNO-2428926 https://reactome.org/PathwayBrowser/#/R-RNO-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Rattus norvegicus 456216 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus 456216 R-RNO-2466068 https://reactome.org/PathwayBrowser/#/R-RNO-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Rattus norvegicus 456216 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus 456216 R-RNO-2468293 https://reactome.org/PathwayBrowser/#/R-RNO-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Rattus norvegicus 456216 R-RNO-2529020 https://reactome.org/PathwayBrowser/#/R-RNO-2529020 CK2 phosphorylates condensin I subunits IEA Rattus norvegicus 456216 R-RNO-2562526 https://reactome.org/PathwayBrowser/#/R-RNO-2562526 PLK1 phosphorylates OPTN IEA Rattus norvegicus 456216 R-RNO-2574840 https://reactome.org/PathwayBrowser/#/R-RNO-2574840 AJUBA facilitates AURKA autophosphorylation IEA Rattus norvegicus 456216 R-RNO-2581474 https://reactome.org/PathwayBrowser/#/R-RNO-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Rattus norvegicus 456216 R-RNO-265682 https://reactome.org/PathwayBrowser/#/R-RNO-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Rattus norvegicus 456216 R-RNO-265783 https://reactome.org/PathwayBrowser/#/R-RNO-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-266082 https://reactome.org/PathwayBrowser/#/R-RNO-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Rattus norvegicus 456216 R-RNO-2682349 https://reactome.org/PathwayBrowser/#/R-RNO-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Rattus norvegicus 456216 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus 456216 R-RNO-2730835 https://reactome.org/PathwayBrowser/#/R-RNO-2730835 Autophosphorylation of PKC-theta IEA Rattus norvegicus 456216 R-RNO-2730841 https://reactome.org/PathwayBrowser/#/R-RNO-2730841 Phosphorylation and activation of VAV IEA Rattus norvegicus 456216 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus 456216 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus 456216 R-RNO-2730856 https://reactome.org/PathwayBrowser/#/R-RNO-2730856 Autophosphorylation of PAK IEA Rattus norvegicus 456216 R-RNO-2730858 https://reactome.org/PathwayBrowser/#/R-RNO-2730858 Autophosphorylation of BTK/ITK IEA Rattus norvegicus 456216 R-RNO-2730862 https://reactome.org/PathwayBrowser/#/R-RNO-2730862 Autophosphorylation of LYN kinase IEA Rattus norvegicus 456216 R-RNO-2730863 https://reactome.org/PathwayBrowser/#/R-RNO-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Rattus norvegicus 456216 R-RNO-2730868 https://reactome.org/PathwayBrowser/#/R-RNO-2730868 Phosphorylation of MEK7 by MEKK1 IEA Rattus norvegicus 456216 R-RNO-2730870 https://reactome.org/PathwayBrowser/#/R-RNO-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Rattus norvegicus 456216 R-RNO-2730876 https://reactome.org/PathwayBrowser/#/R-RNO-2730876 Phosphorylation of IKK-beta by TAK1 IEA Rattus norvegicus 456216 R-RNO-2730881 https://reactome.org/PathwayBrowser/#/R-RNO-2730881 Phosphorylation of PLC-gamma TAS Rattus norvegicus 456216 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus 456216 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus 456216 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus 456216 R-RNO-2730896 https://reactome.org/PathwayBrowser/#/R-RNO-2730896 Phosphorylation of MEK4 by MEKK1 IEA Rattus norvegicus 456216 R-RNO-2730900 https://reactome.org/PathwayBrowser/#/R-RNO-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Rattus norvegicus 456216 R-RNO-2984220 https://reactome.org/PathwayBrowser/#/R-RNO-2984220 CDK1:CCNB phosphorylates NEK9 IEA Rattus norvegicus 456216 R-RNO-2984226 https://reactome.org/PathwayBrowser/#/R-RNO-2984226 PLK1 phosphorylates NEK9 IEA Rattus norvegicus 456216 R-RNO-2990882 https://reactome.org/PathwayBrowser/#/R-RNO-2990882 CDK1 phosphorylates NUP98 IEA Rattus norvegicus 456216 R-RNO-2993898 https://reactome.org/PathwayBrowser/#/R-RNO-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Rattus norvegicus 456216 R-RNO-3000310 https://reactome.org/PathwayBrowser/#/R-RNO-3000310 AURKA phosphorylates PLK1 IEA Rattus norvegicus 456216 R-RNO-3000327 https://reactome.org/PathwayBrowser/#/R-RNO-3000327 PLK1 phosphorylates BORA IEA Rattus norvegicus 456216 R-RNO-3095901 https://reactome.org/PathwayBrowser/#/R-RNO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Rattus norvegicus 456216 R-RNO-3132737 https://reactome.org/PathwayBrowser/#/R-RNO-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Rattus norvegicus 456216 R-RNO-3222006 https://reactome.org/PathwayBrowser/#/R-RNO-3222006 STK11 (LKB1) phosphorylates NUAK1 IEA Rattus norvegicus 456216 R-RNO-3222020 https://reactome.org/PathwayBrowser/#/R-RNO-3222020 NUAK1 phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-3228469 https://reactome.org/PathwayBrowser/#/R-RNO-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Rattus norvegicus 456216 R-RNO-3229102 https://reactome.org/PathwayBrowser/#/R-RNO-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Rattus norvegicus 456216 R-RNO-3238999 https://reactome.org/PathwayBrowser/#/R-RNO-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Rattus norvegicus 456216 R-RNO-3239014 https://reactome.org/PathwayBrowser/#/R-RNO-3239014 MAPKAPK5 phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-3239019 https://reactome.org/PathwayBrowser/#/R-RNO-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Rattus norvegicus 456216 R-RNO-3249371 https://reactome.org/PathwayBrowser/#/R-RNO-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Rattus norvegicus 456216 R-RNO-3249379 https://reactome.org/PathwayBrowser/#/R-RNO-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Rattus norvegicus 456216 R-RNO-3249390 https://reactome.org/PathwayBrowser/#/R-RNO-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Rattus norvegicus 456216 R-RNO-3371422 https://reactome.org/PathwayBrowser/#/R-RNO-3371422 ATP hydrolysis by HSP70 IEA Rattus norvegicus 456216 R-RNO-3371435 https://reactome.org/PathwayBrowser/#/R-RNO-3371435 Constitutive phosphorylation by GSK3 IEA Rattus norvegicus 456216 R-RNO-3371503 https://reactome.org/PathwayBrowser/#/R-RNO-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Rattus norvegicus 456216 R-RNO-3371531 https://reactome.org/PathwayBrowser/#/R-RNO-3371531 Constitutive phosphorylation by pERK1/2 IEA Rattus norvegicus 456216 R-RNO-349426 https://reactome.org/PathwayBrowser/#/R-RNO-349426 Phosphorylation of MDM4 by CHEK2 IEA Rattus norvegicus 456216 R-RNO-349444 https://reactome.org/PathwayBrowser/#/R-RNO-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Rattus norvegicus 456216 R-RNO-349455 https://reactome.org/PathwayBrowser/#/R-RNO-349455 Phosphorylation of MDM4 by ATM IEA Rattus norvegicus 456216 R-RNO-354073 https://reactome.org/PathwayBrowser/#/R-RNO-354073 Autophosphorylation of PTK2 at Y397 IEA Rattus norvegicus 456216 R-RNO-354124 https://reactome.org/PathwayBrowser/#/R-RNO-354124 Phosphorylation of pPTK2 by SRC IEA Rattus norvegicus 456216 R-RNO-372693 https://reactome.org/PathwayBrowser/#/R-RNO-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Rattus norvegicus 456216 R-RNO-373747 https://reactome.org/PathwayBrowser/#/R-RNO-373747 Phosphorylation of nephrin by FYN IEA Rattus norvegicus 456216 R-RNO-373750 https://reactome.org/PathwayBrowser/#/R-RNO-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Rattus norvegicus 456216 R-RNO-374664 https://reactome.org/PathwayBrowser/#/R-RNO-374664 Phosphorylation and activation of Ezrin IEA Rattus norvegicus 456216 R-RNO-374701 https://reactome.org/PathwayBrowser/#/R-RNO-374701 Phosphorylation of DCC by Fyn IEA Rattus norvegicus 456216 R-RNO-3769394 https://reactome.org/PathwayBrowser/#/R-RNO-3769394 AKT phosphorylates CBY1 IEA Rattus norvegicus 456216 R-RNO-377186 https://reactome.org/PathwayBrowser/#/R-RNO-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Rattus norvegicus 456216 R-RNO-3772435 https://reactome.org/PathwayBrowser/#/R-RNO-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Rattus norvegicus 456216 R-RNO-3772436 https://reactome.org/PathwayBrowser/#/R-RNO-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Rattus norvegicus 456216 R-RNO-377640 https://reactome.org/PathwayBrowser/#/R-RNO-377640 Autophosphorylation of SRC IEA Rattus norvegicus 456216 R-RNO-3788705 https://reactome.org/PathwayBrowser/#/R-RNO-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Rattus norvegicus 456216 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 456216 R-RNO-379832 https://reactome.org/PathwayBrowser/#/R-RNO-379832 CaMKIV phosphorylates Creb1 TAS Rattus norvegicus 456216 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 456216 R-RNO-380272 https://reactome.org/PathwayBrowser/#/R-RNO-380272 Plk1-mediated phosphorylation of Nlp IEA Rattus norvegicus 456216 R-RNO-380278 https://reactome.org/PathwayBrowser/#/R-RNO-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Rattus norvegicus 456216 R-RNO-380780 https://reactome.org/PathwayBrowser/#/R-RNO-380780 Activation of Src IEA Rattus norvegicus 456216 R-RNO-380927 https://reactome.org/PathwayBrowser/#/R-RNO-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Rattus norvegicus 456216 R-RNO-381091 https://reactome.org/PathwayBrowser/#/R-RNO-381091 IRE1 dimer autophosphorylates IEA Rattus norvegicus 456216 R-RNO-381111 https://reactome.org/PathwayBrowser/#/R-RNO-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Rattus norvegicus 456216 R-RNO-382553 https://reactome.org/PathwayBrowser/#/R-RNO-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Rattus norvegicus 456216 R-RNO-382560 https://reactome.org/PathwayBrowser/#/R-RNO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Rattus norvegicus 456216 R-RNO-382575 https://reactome.org/PathwayBrowser/#/R-RNO-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Rattus norvegicus 456216 R-RNO-383190 https://reactome.org/PathwayBrowser/#/R-RNO-383190 HCO3- transport through ion channel IEA Rattus norvegicus 456216 R-RNO-3857329 https://reactome.org/PathwayBrowser/#/R-RNO-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Rattus norvegicus 456216 R-RNO-388831 https://reactome.org/PathwayBrowser/#/R-RNO-388831 Phosphorylation of CD28 IEA Rattus norvegicus 456216 R-RNO-388833 https://reactome.org/PathwayBrowser/#/R-RNO-388833 Phosphorylation of CTLA-4 IEA Rattus norvegicus 456216 R-RNO-389083 https://reactome.org/PathwayBrowser/#/R-RNO-389083 Autophosphorylation of PDGF alpha receptors IEA Rattus norvegicus 456216 R-RNO-389086 https://reactome.org/PathwayBrowser/#/R-RNO-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Rattus norvegicus 456216 R-RNO-389158 https://reactome.org/PathwayBrowser/#/R-RNO-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-389354 https://reactome.org/PathwayBrowser/#/R-RNO-389354 Activation of Vav1 IEA Rattus norvegicus 456216 R-RNO-389756 https://reactome.org/PathwayBrowser/#/R-RNO-389756 AKT interacts and phosphorylates Cot IEA Rattus norvegicus 456216 R-RNO-389762 https://reactome.org/PathwayBrowser/#/R-RNO-389762 Phosphorylation of PD-1 IEA Rattus norvegicus 456216 R-RNO-390593 https://reactome.org/PathwayBrowser/#/R-RNO-390593 ATP Hydrolysis By Myosin IEA Rattus norvegicus 456216 R-RNO-390597 https://reactome.org/PathwayBrowser/#/R-RNO-390597 Release Of ADP From Myosin IEA Rattus norvegicus 456216 R-RNO-391266 https://reactome.org/PathwayBrowser/#/R-RNO-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Rattus norvegicus 456216 R-RNO-392195 https://reactome.org/PathwayBrowser/#/R-RNO-392195 Gi activation by P2Y purinoceptor 12 IEA Rattus norvegicus 456216 R-RNO-392300 https://reactome.org/PathwayBrowser/#/R-RNO-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-392530 https://reactome.org/PathwayBrowser/#/R-RNO-392530 p-S400-Cot phosphorylates NIK IEA Rattus norvegicus 456216 R-RNO-392752 https://reactome.org/PathwayBrowser/#/R-RNO-392752 Phosphorylation of L1 by CK-II IEA Rattus norvegicus 456216 R-RNO-3928578 https://reactome.org/PathwayBrowser/#/R-RNO-3928578 EPH receptors autophosphorylate IEA Rattus norvegicus 456216 R-RNO-3928604 https://reactome.org/PathwayBrowser/#/R-RNO-3928604 SFKs phosphorylate VAV2,3 IEA Rattus norvegicus 456216 R-RNO-3928620 https://reactome.org/PathwayBrowser/#/R-RNO-3928620 PAK1 autophosphorylates IEA Rattus norvegicus 456216 R-RNO-3928625 https://reactome.org/PathwayBrowser/#/R-RNO-3928625 PAKs autophosphorylate IEA Rattus norvegicus 456216 R-RNO-3928627 https://reactome.org/PathwayBrowser/#/R-RNO-3928627 EPHB phosphorylates TIAM1 IEA Rattus norvegicus 456216 R-RNO-3928640 https://reactome.org/PathwayBrowser/#/R-RNO-3928640 PAKs phosphorylate MLC IEA Rattus norvegicus 456216 R-RNO-399939 https://reactome.org/PathwayBrowser/#/R-RNO-399939 Autophosphorylation of PAK IEA Rattus norvegicus 456216 R-RNO-399944 https://reactome.org/PathwayBrowser/#/R-RNO-399944 Phosphorylation of CRMPs by Cdk5 IEA Rattus norvegicus 456216 R-RNO-399947 https://reactome.org/PathwayBrowser/#/R-RNO-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Rattus norvegicus 456216 R-RNO-399951 https://reactome.org/PathwayBrowser/#/R-RNO-399951 Phosphorylation of CRMPs by GSK3beta IEA Rattus norvegicus 456216 R-RNO-399952 https://reactome.org/PathwayBrowser/#/R-RNO-399952 Phosphorylation of LIMK-1 by PAK IEA Rattus norvegicus 456216 R-RNO-399978 https://reactome.org/PathwayBrowser/#/R-RNO-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Rattus norvegicus 456216 R-RNO-4085028 https://reactome.org/PathwayBrowser/#/R-RNO-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Rattus norvegicus 456216 R-RNO-4086410 https://reactome.org/PathwayBrowser/#/R-RNO-4086410 CDK1 phosphorylates BORA IEA Rattus norvegicus 456216 R-RNO-4088024 https://reactome.org/PathwayBrowser/#/R-RNO-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Rattus norvegicus 456216 R-RNO-4088134 https://reactome.org/PathwayBrowser/#/R-RNO-4088134 PLK1 phosphorylates FOXM1 IEA Rattus norvegicus 456216 R-RNO-4093332 https://reactome.org/PathwayBrowser/#/R-RNO-4093332 p-EPHB phosphorylates SDC2 IEA Rattus norvegicus 456216 R-RNO-416320 https://reactome.org/PathwayBrowser/#/R-RNO-416320 Trafficking of GluR1-containing AMPA receptors IEA Rattus norvegicus 456216 R-RNO-416639 https://reactome.org/PathwayBrowser/#/R-RNO-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Rattus norvegicus 456216 R-RNO-416985 https://reactome.org/PathwayBrowser/#/R-RNO-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Rattus norvegicus 456216 R-RNO-417829 https://reactome.org/PathwayBrowser/#/R-RNO-417829 P2RY12 binds ADP IEA Rattus norvegicus 456216 R-RNO-417843 https://reactome.org/PathwayBrowser/#/R-RNO-417843 P2Y13 binds ADP IEA Rattus norvegicus 456216 R-RNO-417908 https://reactome.org/PathwayBrowser/#/R-RNO-417908 P2RY1 binds ADP IEA Rattus norvegicus 456216 R-RNO-418845 https://reactome.org/PathwayBrowser/#/R-RNO-418845 Activation of caspase-3 IEA Rattus norvegicus 456216 R-RNO-419644 https://reactome.org/PathwayBrowser/#/R-RNO-419644 Transphosphorylation of pLIMK1 IEA Rattus norvegicus 456216 R-RNO-419646 https://reactome.org/PathwayBrowser/#/R-RNO-419646 SEMA4D interacts with Plexin-B1:Met IEA Rattus norvegicus 456216 R-RNO-421007 https://reactome.org/PathwayBrowser/#/R-RNO-421007 Endocytosis of Ca impermeable AMPA receptors IEA Rattus norvegicus 456216 R-RNO-421836 https://reactome.org/PathwayBrowser/#/R-RNO-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Rattus norvegicus 456216 R-RNO-426240 https://reactome.org/PathwayBrowser/#/R-RNO-426240 DAG kinase produces phosphatidic acid from DAG IEA Rattus norvegicus 456216 R-RNO-428273 https://reactome.org/PathwayBrowser/#/R-RNO-428273 SPHK1 phosphorylates sphingoid IEA Rattus norvegicus 456216 R-RNO-428941 https://reactome.org/PathwayBrowser/#/R-RNO-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Rattus norvegicus 456216 R-RNO-428961 https://reactome.org/PathwayBrowser/#/R-RNO-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Rattus norvegicus 456216 R-RNO-429016 https://reactome.org/PathwayBrowser/#/R-RNO-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Rattus norvegicus 456216 R-RNO-429157 https://reactome.org/PathwayBrowser/#/R-RNO-429157 ABCC4 accumulation of dense granule contents IEA Rattus norvegicus 456216 R-RNO-429441 https://reactome.org/PathwayBrowser/#/R-RNO-429441 SYK activation by SRC IEA Rattus norvegicus 456216 R-RNO-429449 https://reactome.org/PathwayBrowser/#/R-RNO-429449 Syk activation leads to SLP-76 activation IEA Rattus norvegicus 456216 R-RNO-432129 https://reactome.org/PathwayBrowser/#/R-RNO-432129 FGR binds and phosphorylates LRP8 IEA Rattus norvegicus 456216 R-RNO-432148 https://reactome.org/PathwayBrowser/#/R-RNO-432148 Fgr may phosphorylate p38 MAPK IEA Rattus norvegicus 456216 R-RNO-432232 https://reactome.org/PathwayBrowser/#/R-RNO-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Rattus norvegicus 456216 R-RNO-432688 https://reactome.org/PathwayBrowser/#/R-RNO-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating IEA Rattus norvegicus 456216 R-RNO-4332358 https://reactome.org/PathwayBrowser/#/R-RNO-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Rattus norvegicus 456216 R-RNO-4332363 https://reactome.org/PathwayBrowser/#/R-RNO-4332363 Autophosphorylation and activation of CAMK2 IEA Rattus norvegicus 456216 R-RNO-434836 https://reactome.org/PathwayBrowser/#/R-RNO-434836 Syk/Lck phosphorylate LAT IEA Rattus norvegicus 456216 R-RNO-435244 https://reactome.org/PathwayBrowser/#/R-RNO-435244 PECAM1 is phosphorylated IEA Rattus norvegicus 456216 R-RNO-437162 https://reactome.org/PathwayBrowser/#/R-RNO-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-437185 https://reactome.org/PathwayBrowser/#/R-RNO-437185 PDK1 activates PKC zeta TAS Rattus norvegicus 456216 R-RNO-4411383 https://reactome.org/PathwayBrowser/#/R-RNO-4411383 NLK phosphorylates TCF/LEF IEA Rattus norvegicus 456216 R-RNO-4411402 https://reactome.org/PathwayBrowser/#/R-RNO-4411402 Activation of NLK IEA Rattus norvegicus 456216 R-RNO-4420117 https://reactome.org/PathwayBrowser/#/R-RNO-4420117 VEGFR2 autophosphorylates IEA Rattus norvegicus 456216 R-RNO-4420121 https://reactome.org/PathwayBrowser/#/R-RNO-4420121 SFKs phosphorylate PLCG1 IEA Rattus norvegicus 456216 R-RNO-4420128 https://reactome.org/PathwayBrowser/#/R-RNO-4420128 SRC-1 phosphorylates SHB IEA Rattus norvegicus 456216 R-RNO-4420206 https://reactome.org/PathwayBrowser/#/R-RNO-4420206 Phosphorylation of SRC-1 IEA Rattus norvegicus 456216 R-RNO-442724 https://reactome.org/PathwayBrowser/#/R-RNO-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Rattus norvegicus 456216 R-RNO-442749 https://reactome.org/PathwayBrowser/#/R-RNO-442749 CaMKK autophosphorylates in the nucleus IEA Rattus norvegicus 456216 R-RNO-445072 https://reactome.org/PathwayBrowser/#/R-RNO-445072 Interaction of PAK1 with Rac1-GTP IEA Rattus norvegicus 456216 R-RNO-445079 https://reactome.org/PathwayBrowser/#/R-RNO-445079 Phosphorylation of L1 by ERK IEA Rattus norvegicus 456216 R-RNO-445080 https://reactome.org/PathwayBrowser/#/R-RNO-445080 Phosphorylation of Neurofascin TAS Rattus norvegicus 456216 R-RNO-445084 https://reactome.org/PathwayBrowser/#/R-RNO-445084 Phosphorylation of L1 by SRC IEA Rattus norvegicus 456216 R-RNO-445705 https://reactome.org/PathwayBrowser/#/R-RNO-445705 Release Of ADP From Myosin IEA Rattus norvegicus 456216 R-RNO-445813 https://reactome.org/PathwayBrowser/#/R-RNO-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Rattus norvegicus 456216 R-RNO-446634 https://reactome.org/PathwayBrowser/#/R-RNO-446634 IRAK4 is activated by autophosphorylation IEA Rattus norvegicus 456216 R-RNO-446694 https://reactome.org/PathwayBrowser/#/R-RNO-446694 IRAK4 phosphorylates IRAK1 IEA Rattus norvegicus 456216 R-RNO-446701 https://reactome.org/PathwayBrowser/#/R-RNO-446701 IRAK4-activated IRAK1 autophosphorylates IEA Rattus norvegicus 456216 R-RNO-447074 https://reactome.org/PathwayBrowser/#/R-RNO-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Rattus norvegicus 456216 R-RNO-448955 https://reactome.org/PathwayBrowser/#/R-RNO-448955 Phosphorylation of MEF2 proteins by p38 IEA Rattus norvegicus 456216 R-RNO-450222 https://reactome.org/PathwayBrowser/#/R-RNO-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Rattus norvegicus 456216 R-RNO-450325 https://reactome.org/PathwayBrowser/#/R-RNO-450325 c-FOS activation by phospho ERK1/2 IEA Rattus norvegicus 456216 R-RNO-450333 https://reactome.org/PathwayBrowser/#/R-RNO-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Rattus norvegicus 456216 R-RNO-450337 https://reactome.org/PathwayBrowser/#/R-RNO-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Rattus norvegicus 456216 R-RNO-450346 https://reactome.org/PathwayBrowser/#/R-RNO-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Rattus norvegicus 456216 R-RNO-450463 https://reactome.org/PathwayBrowser/#/R-RNO-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Rattus norvegicus 456216 R-RNO-450474 https://reactome.org/PathwayBrowser/#/R-RNO-450474 MK2 phosphorylates BRF1 IEA Rattus norvegicus 456216 R-RNO-450490 https://reactome.org/PathwayBrowser/#/R-RNO-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Rattus norvegicus 456216 R-RNO-450499 https://reactome.org/PathwayBrowser/#/R-RNO-450499 Protein Kinase B (AKT) phosphorylates KSRP IEA Rattus norvegicus 456216 R-RNO-450533 https://reactome.org/PathwayBrowser/#/R-RNO-450533 PKCdelta phosphorylates HuR IEA Rattus norvegicus 456216 R-RNO-450550 https://reactome.org/PathwayBrowser/#/R-RNO-450550 PKCalpha phosphorylates HuR IEA Rattus norvegicus 456216 R-RNO-450827 https://reactome.org/PathwayBrowser/#/R-RNO-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Rattus norvegicus 456216 R-RNO-451942 https://reactome.org/PathwayBrowser/#/R-RNO-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Rattus norvegicus 456216 R-RNO-452097 https://reactome.org/PathwayBrowser/#/R-RNO-452097 Recruited STAT5 is phosphorylated IEA Rattus norvegicus 456216 R-RNO-452100 https://reactome.org/PathwayBrowser/#/R-RNO-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Rattus norvegicus 456216 R-RNO-452122 https://reactome.org/PathwayBrowser/#/R-RNO-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Rattus norvegicus 456216 R-RNO-453200 https://reactome.org/PathwayBrowser/#/R-RNO-453200 SYK autophosphorylates IEA Rattus norvegicus 456216 R-RNO-4793911 https://reactome.org/PathwayBrowser/#/R-RNO-4793911 MAPKAPK2 phosphorylates HSF1 IEA Rattus norvegicus 456216 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 456216 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 456216 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 456216 R-RNO-504054 https://reactome.org/PathwayBrowser/#/R-RNO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Rattus norvegicus 456216 R-RNO-508040 https://reactome.org/PathwayBrowser/#/R-RNO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Rattus norvegicus 456216 R-RNO-5082387 https://reactome.org/PathwayBrowser/#/R-RNO-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Rattus norvegicus 456216 R-RNO-5082405 https://reactome.org/PathwayBrowser/#/R-RNO-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Rattus norvegicus 456216 R-RNO-508282 https://reactome.org/PathwayBrowser/#/R-RNO-508282 SYK is a substrate for JAK1 IEA Rattus norvegicus 456216 R-RNO-508308 https://reactome.org/PathwayBrowser/#/R-RNO-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Rattus norvegicus 456216 R-RNO-5138432 https://reactome.org/PathwayBrowser/#/R-RNO-5138432 DVL2 is phosphorylated by PKC IEA Rattus norvegicus 456216 R-RNO-5195402 https://reactome.org/PathwayBrowser/#/R-RNO-5195402 CDK1 phosphorylates LPIN IEA Rattus norvegicus 456216 R-RNO-5213464 https://reactome.org/PathwayBrowser/#/R-RNO-5213464 RIPK1 is phosphorylated IEA Rattus norvegicus 456216 R-RNO-5213466 https://reactome.org/PathwayBrowser/#/R-RNO-5213466 RIPK3 is phosphorylated IEA Rattus norvegicus 456216 R-RNO-5218640 https://reactome.org/PathwayBrowser/#/R-RNO-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Rattus norvegicus 456216 R-RNO-5218642 https://reactome.org/PathwayBrowser/#/R-RNO-5218642 PTK2 autophosphorylates IEA Rattus norvegicus 456216 R-RNO-5218804 https://reactome.org/PathwayBrowser/#/R-RNO-5218804 p38 MAPK activation by VEGFR IEA Rattus norvegicus 456216 R-RNO-5218805 https://reactome.org/PathwayBrowser/#/R-RNO-5218805 PKC autophosphorylates IEA Rattus norvegicus 456216 R-RNO-5218806 https://reactome.org/PathwayBrowser/#/R-RNO-5218806 FYN autophosphorylates IEA Rattus norvegicus 456216 R-RNO-5218809 https://reactome.org/PathwayBrowser/#/R-RNO-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Rattus norvegicus 456216 R-RNO-5218812 https://reactome.org/PathwayBrowser/#/R-RNO-5218812 FYN phosphorylates PAK2 IEA Rattus norvegicus 456216 R-RNO-5218814 https://reactome.org/PathwayBrowser/#/R-RNO-5218814 PAK2 autophorylates IEA Rattus norvegicus 456216 R-RNO-5218819 https://reactome.org/PathwayBrowser/#/R-RNO-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-5218820 https://reactome.org/PathwayBrowser/#/R-RNO-5218820 Src kinases phosphorylate VAV IEA Rattus norvegicus 456216 R-RNO-5218821 https://reactome.org/PathwayBrowser/#/R-RNO-5218821 PDK1 phosphorylates PKC IEA Rattus norvegicus 456216 R-RNO-5218823 https://reactome.org/PathwayBrowser/#/R-RNO-5218823 PKC phosphorylates sphingosine kinase 1 IEA Rattus norvegicus 456216 R-RNO-5218826 https://reactome.org/PathwayBrowser/#/R-RNO-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Rattus norvegicus 456216 R-RNO-5218830 https://reactome.org/PathwayBrowser/#/R-RNO-5218830 SRC-1 phosphorylates PTK2-beta IEA Rattus norvegicus 456216 R-RNO-5218845 https://reactome.org/PathwayBrowser/#/R-RNO-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Rattus norvegicus 456216 R-RNO-5218851 https://reactome.org/PathwayBrowser/#/R-RNO-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Rattus norvegicus 456216 R-RNO-5218854 https://reactome.org/PathwayBrowser/#/R-RNO-5218854 p-Y420-FYN is phosphorylated on S21 IEA Rattus norvegicus 456216 R-RNO-5218906 https://reactome.org/PathwayBrowser/#/R-RNO-5218906 RIPK3 phosphorylates MLKL IEA Rattus norvegicus 456216 R-RNO-5218916 https://reactome.org/PathwayBrowser/#/R-RNO-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Rattus norvegicus 456216 R-RNO-5223317 https://reactome.org/PathwayBrowser/#/R-RNO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Rattus norvegicus 456216 R-RNO-5229194 https://reactome.org/PathwayBrowser/#/R-RNO-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Rattus norvegicus 456216 R-RNO-5229343 https://reactome.org/PathwayBrowser/#/R-RNO-5229343 AXIN is phosphorylated in the destruction complex IEA Rattus norvegicus 456216 R-RNO-5244669 https://reactome.org/PathwayBrowser/#/R-RNO-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Rattus norvegicus 456216 R-RNO-5251955 https://reactome.org/PathwayBrowser/#/R-RNO-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Rattus norvegicus 456216 R-RNO-5251959 https://reactome.org/PathwayBrowser/#/R-RNO-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Rattus norvegicus 456216 R-RNO-5251989 https://reactome.org/PathwayBrowser/#/R-RNO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Rattus norvegicus 456216 R-RNO-5252079 https://reactome.org/PathwayBrowser/#/R-RNO-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Rattus norvegicus 456216 R-RNO-5357429 https://reactome.org/PathwayBrowser/#/R-RNO-5357429 AXL autophosphorylates on Y779 and Y821 IEA Rattus norvegicus 456216 R-RNO-5357472 https://reactome.org/PathwayBrowser/#/R-RNO-5357472 PAK1-3 autophosphorylates IEA Rattus norvegicus 456216 R-RNO-5357477 https://reactome.org/PathwayBrowser/#/R-RNO-5357477 PAK1-3 phosphorylates VE-cadherin IEA Rattus norvegicus 456216 R-RNO-5357831 https://reactome.org/PathwayBrowser/#/R-RNO-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Rattus norvegicus 456216 R-RNO-5358525 https://reactome.org/PathwayBrowser/#/R-RNO-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Rattus norvegicus 456216 R-RNO-5358912 https://reactome.org/PathwayBrowser/#/R-RNO-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Rattus norvegicus 456216 R-RNO-5362459 https://reactome.org/PathwayBrowser/#/R-RNO-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Rattus norvegicus 456216 R-RNO-5444516 https://reactome.org/PathwayBrowser/#/R-RNO-5444516 Formation of MSH2:MSH6 Complex IEA Rattus norvegicus 456216 R-RNO-548972 https://reactome.org/PathwayBrowser/#/R-RNO-548972 Phosphorylation of ITIM in SIRP alpha TAS Rattus norvegicus 456216 R-RNO-5578777 https://reactome.org/PathwayBrowser/#/R-RNO-5578777 DMPK phosphorylates PLN IEA Rattus norvegicus 456216 R-RNO-5607722 https://reactome.org/PathwayBrowser/#/R-RNO-5607722 Active NIK phosphorylates IKKA dimer IEA Rattus norvegicus 456216 R-RNO-5607726 https://reactome.org/PathwayBrowser/#/R-RNO-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Rattus norvegicus 456216 R-RNO-5607732 https://reactome.org/PathwayBrowser/#/R-RNO-5607732 K63polyUb-TAK1 autophosphorylates IEA Rattus norvegicus 456216 R-RNO-5607740 https://reactome.org/PathwayBrowser/#/R-RNO-5607740 PKC-delta phosphorylates CARD9 IEA Rattus norvegicus 456216 R-RNO-5607742 https://reactome.org/PathwayBrowser/#/R-RNO-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Rattus norvegicus 456216 R-RNO-5607750 https://reactome.org/PathwayBrowser/#/R-RNO-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Rattus norvegicus 456216 R-RNO-5610720 https://reactome.org/PathwayBrowser/#/R-RNO-5610720 PKA phosphorylates GLI3 IEA Rattus norvegicus 456216 R-RNO-5610722 https://reactome.org/PathwayBrowser/#/R-RNO-5610722 CK1 phosphorylates p-GLI3 IEA Rattus norvegicus 456216 R-RNO-5610732 https://reactome.org/PathwayBrowser/#/R-RNO-5610732 GSK3 phosphorylates p-GLI3 IEA Rattus norvegicus 456216 R-RNO-5617179 https://reactome.org/PathwayBrowser/#/R-RNO-5617179 PRKACA phosphorylates TNNI3 IEA Rattus norvegicus 456216 R-RNO-5617182 https://reactome.org/PathwayBrowser/#/R-RNO-5617182 PRKACA phosphorylates PLN IEA Rattus norvegicus 456216 R-RNO-5618085 https://reactome.org/PathwayBrowser/#/R-RNO-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Rattus norvegicus 456216 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 456216 R-RNO-5618098 https://reactome.org/PathwayBrowser/#/R-RNO-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Rattus norvegicus 456216 R-RNO-5618105 https://reactome.org/PathwayBrowser/#/R-RNO-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Rattus norvegicus 456216 R-RNO-5618107 https://reactome.org/PathwayBrowser/#/R-RNO-5618107 ATP binding to HSP90 triggers conformation change IEA Rattus norvegicus 456216 R-RNO-5618110 https://reactome.org/PathwayBrowser/#/R-RNO-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Rattus norvegicus 456216 R-RNO-5621355 https://reactome.org/PathwayBrowser/#/R-RNO-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Rattus norvegicus 456216 R-RNO-5621363 https://reactome.org/PathwayBrowser/#/R-RNO-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Rattus norvegicus 456216 R-RNO-5621370 https://reactome.org/PathwayBrowser/#/R-RNO-5621370 SYK autophosphorylates IEA Rattus norvegicus 456216 R-RNO-5623667 https://reactome.org/PathwayBrowser/#/R-RNO-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Rattus norvegicus 456216 R-RNO-5624486 https://reactome.org/PathwayBrowser/#/R-RNO-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Rattus norvegicus 456216 R-RNO-5624492 https://reactome.org/PathwayBrowser/#/R-RNO-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Rattus norvegicus 456216 R-RNO-5625784 https://reactome.org/PathwayBrowser/#/R-RNO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Rattus norvegicus 456216 R-RNO-5627775 https://reactome.org/PathwayBrowser/#/R-RNO-5627775 Autophosphorylation of PAK1,2,3 IEA Rattus norvegicus 456216 R-RNO-5635842 https://reactome.org/PathwayBrowser/#/R-RNO-5635842 ULK3 phosphorylates GLI IEA Rattus norvegicus 456216 R-RNO-5654147 https://reactome.org/PathwayBrowser/#/R-RNO-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Rattus norvegicus 456216 R-RNO-5654149 https://reactome.org/PathwayBrowser/#/R-RNO-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Rattus norvegicus 456216 R-RNO-5654151 https://reactome.org/PathwayBrowser/#/R-RNO-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Rattus norvegicus 456216 R-RNO-5654222 https://reactome.org/PathwayBrowser/#/R-RNO-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Rattus norvegicus 456216 R-RNO-5654397 https://reactome.org/PathwayBrowser/#/R-RNO-5654397 Activated FGFR2 phosphorylates FRS2 IEA Rattus norvegicus 456216 R-RNO-5654407 https://reactome.org/PathwayBrowser/#/R-RNO-5654407 Activated FGFR2 phosphorylates SHC1 IEA Rattus norvegicus 456216 R-RNO-5654408 https://reactome.org/PathwayBrowser/#/R-RNO-5654408 Activated FGFR3 phosphorylates FRS2 IEA Rattus norvegicus 456216 R-RNO-5654418 https://reactome.org/PathwayBrowser/#/R-RNO-5654418 Activated FGFR4 phosphorylates FRS2 IEA Rattus norvegicus 456216 R-RNO-5654428 https://reactome.org/PathwayBrowser/#/R-RNO-5654428 Activated FGFR4 phosphorylates SHC1 IEA Rattus norvegicus 456216 R-RNO-5654560 https://reactome.org/PathwayBrowser/#/R-RNO-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Rattus norvegicus 456216 R-RNO-5654562 https://reactome.org/PathwayBrowser/#/R-RNO-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Rattus norvegicus 456216 R-RNO-5654565 https://reactome.org/PathwayBrowser/#/R-RNO-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. IEA Rattus norvegicus 456216 R-RNO-5654566 https://reactome.org/PathwayBrowser/#/R-RNO-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Rattus norvegicus 456216 R-RNO-5654575 https://reactome.org/PathwayBrowser/#/R-RNO-5654575 Activated FGFR1 phosphorylates FRS2 IEA Rattus norvegicus 456216 R-RNO-5654578 https://reactome.org/PathwayBrowser/#/R-RNO-5654578 Activated FGFR1 phosphorylates FRS3 IEA Rattus norvegicus 456216 R-RNO-5654582 https://reactome.org/PathwayBrowser/#/R-RNO-5654582 Activated FGFR1 phosphorylates SHC1 IEA Rattus norvegicus 456216 R-RNO-5654587 https://reactome.org/PathwayBrowser/#/R-RNO-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Rattus norvegicus 456216 R-RNO-5654605 https://reactome.org/PathwayBrowser/#/R-RNO-5654605 Activated FGFR2 phosphorylates FRS3 IEA Rattus norvegicus 456216 R-RNO-5654607 https://reactome.org/PathwayBrowser/#/R-RNO-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Rattus norvegicus 456216 R-RNO-5654628 https://reactome.org/PathwayBrowser/#/R-RNO-5654628 Activated FGFR3 phosphorylates FRS3 IEA Rattus norvegicus 456216 R-RNO-5654631 https://reactome.org/PathwayBrowser/#/R-RNO-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Rattus norvegicus 456216 R-RNO-5654634 https://reactome.org/PathwayBrowser/#/R-RNO-5654634 Activated FGFR3 phosphorylates SHC1 IEA Rattus norvegicus 456216 R-RNO-5654653 https://reactome.org/PathwayBrowser/#/R-RNO-5654653 Activated FGFR4 phosphorylates FRS3 IEA Rattus norvegicus 456216 R-RNO-5654655 https://reactome.org/PathwayBrowser/#/R-RNO-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Rattus norvegicus 456216 R-RNO-5654690 https://reactome.org/PathwayBrowser/#/R-RNO-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-5654692 https://reactome.org/PathwayBrowser/#/R-RNO-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-5654697 https://reactome.org/PathwayBrowser/#/R-RNO-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-5654701 https://reactome.org/PathwayBrowser/#/R-RNO-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-5654705 https://reactome.org/PathwayBrowser/#/R-RNO-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-5654709 https://reactome.org/PathwayBrowser/#/R-RNO-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-5654714 https://reactome.org/PathwayBrowser/#/R-RNO-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-5654717 https://reactome.org/PathwayBrowser/#/R-RNO-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-5654989 https://reactome.org/PathwayBrowser/#/R-RNO-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Rattus norvegicus 456216 R-RNO-5662466 https://reactome.org/PathwayBrowser/#/R-RNO-5662466 XYLB phosphorylates D-xylulose IEA Rattus norvegicus 456216 R-RNO-5665868 https://reactome.org/PathwayBrowser/#/R-RNO-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Rattus norvegicus 456216 R-RNO-5666160 https://reactome.org/PathwayBrowser/#/R-RNO-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Rattus norvegicus 456216 R-RNO-5668545 https://reactome.org/PathwayBrowser/#/R-RNO-5668545 NIK autophosphorylates on T559 IEA Rattus norvegicus 456216 R-RNO-5668932 https://reactome.org/PathwayBrowser/#/R-RNO-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Rattus norvegicus 456216 R-RNO-5668947 https://reactome.org/PathwayBrowser/#/R-RNO-5668947 PAK1 phosphorylates myosin phosphatase IEA Rattus norvegicus 456216 R-RNO-5668984 https://reactome.org/PathwayBrowser/#/R-RNO-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Rattus norvegicus 456216 R-RNO-5669250 https://reactome.org/PathwayBrowser/#/R-RNO-5669250 PAK1 phosphorylates FLNA IEA Rattus norvegicus 456216 R-RNO-5671749 https://reactome.org/PathwayBrowser/#/R-RNO-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Rattus norvegicus 456216 R-RNO-5671763 https://reactome.org/PathwayBrowser/#/R-RNO-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Rattus norvegicus 456216 R-RNO-5672008 https://reactome.org/PathwayBrowser/#/R-RNO-5672008 Thr-180 of ULK1 is phosphorylated IEA Rattus norvegicus 456216 R-RNO-5672010 https://reactome.org/PathwayBrowser/#/R-RNO-5672010 Active MTORC1 phosphorylates ULK1 IEA Rattus norvegicus 456216 R-RNO-5672012 https://reactome.org/PathwayBrowser/#/R-RNO-5672012 Beclin-1 complex phosphorylates PtdIns IEA Rattus norvegicus 456216 R-RNO-5672027 https://reactome.org/PathwayBrowser/#/R-RNO-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Rattus norvegicus 456216 R-RNO-5672828 https://reactome.org/PathwayBrowser/#/R-RNO-5672828 mTORC1 phosphorylates AKT1S1 IEA Rattus norvegicus 456216 R-RNO-5672948 https://reactome.org/PathwayBrowser/#/R-RNO-5672948 MARK3 phosphorylates KSR1 IEA Rattus norvegicus 456216 R-RNO-5672969 https://reactome.org/PathwayBrowser/#/R-RNO-5672969 Phosphorylation of RAF IEA Rattus norvegicus 456216 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 456216 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 456216 R-RNO-5673768 https://reactome.org/PathwayBrowser/#/R-RNO-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Rattus norvegicus 456216 R-RNO-5674130 https://reactome.org/PathwayBrowser/#/R-RNO-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Rattus norvegicus 456216 R-RNO-5674373 https://reactome.org/PathwayBrowser/#/R-RNO-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Rattus norvegicus 456216 R-RNO-5674496 https://reactome.org/PathwayBrowser/#/R-RNO-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Rattus norvegicus 456216 R-RNO-5675194 https://reactome.org/PathwayBrowser/#/R-RNO-5675194 Activated MAPK phosphorylates RAF1 IEA Rattus norvegicus 456216 R-RNO-5675198 https://reactome.org/PathwayBrowser/#/R-RNO-5675198 Activated MAPKs phosphorylate BRAF IEA Rattus norvegicus 456216 R-RNO-5675868 https://reactome.org/PathwayBrowser/#/R-RNO-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Rattus norvegicus 456216 R-RNO-5678706 https://reactome.org/PathwayBrowser/#/R-RNO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Rattus norvegicus 456216 R-RNO-5678863 https://reactome.org/PathwayBrowser/#/R-RNO-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-5679041 https://reactome.org/PathwayBrowser/#/R-RNO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-5679205 https://reactome.org/PathwayBrowser/#/R-RNO-5679205 ULK1 phosphorylates Beclin-1 IEA Rattus norvegicus 456216 R-RNO-5682026 https://reactome.org/PathwayBrowser/#/R-RNO-5682026 MRN bound to shortened telomeres activates ATM IEA Rattus norvegicus 456216 R-RNO-5682101 https://reactome.org/PathwayBrowser/#/R-RNO-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Rattus norvegicus 456216 R-RNO-5682285 https://reactome.org/PathwayBrowser/#/R-RNO-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-5682598 https://reactome.org/PathwayBrowser/#/R-RNO-5682598 ATM phosphorylates HERC2 IEA Rattus norvegicus 456216 R-RNO-5682983 https://reactome.org/PathwayBrowser/#/R-RNO-5682983 ATM phosphorylates WHSC1 IEA Rattus norvegicus 456216 R-RNO-5683425 https://reactome.org/PathwayBrowser/#/R-RNO-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Rattus norvegicus 456216 R-RNO-5683714 https://reactome.org/PathwayBrowser/#/R-RNO-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Rattus norvegicus 456216 R-RNO-5683792 https://reactome.org/PathwayBrowser/#/R-RNO-5683792 p-T68-CHEK2 autophosphorylates IEA Rattus norvegicus 456216 R-RNO-5683801 https://reactome.org/PathwayBrowser/#/R-RNO-5683801 CHEK2 phosphorylates BRCA1 IEA Rattus norvegicus 456216 R-RNO-5683930 https://reactome.org/PathwayBrowser/#/R-RNO-5683930 WICH phosphorylates H2AFX on Y142 IEA Rattus norvegicus 456216 R-RNO-5683964 https://reactome.org/PathwayBrowser/#/R-RNO-5683964 ATM phosphorylates EYA1-4 IEA Rattus norvegicus 456216 R-RNO-5684096 https://reactome.org/PathwayBrowser/#/R-RNO-5684096 CDK2 phosphorylates RBBP8 IEA Rattus norvegicus 456216 R-RNO-5684140 https://reactome.org/PathwayBrowser/#/R-RNO-5684140 ATM phosphorylates RBBP8 IEA Rattus norvegicus 456216 R-RNO-5684806 https://reactome.org/PathwayBrowser/#/R-RNO-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN IEA Rattus norvegicus 456216 R-RNO-5684887 https://reactome.org/PathwayBrowser/#/R-RNO-5684887 Activation of CHEK1 at resected DNA DSBs IEA Rattus norvegicus 456216 R-RNO-5685156 https://reactome.org/PathwayBrowser/#/R-RNO-5685156 ATR phosphorylates RPA2 IEA Rattus norvegicus 456216 R-RNO-5685230 https://reactome.org/PathwayBrowser/#/R-RNO-5685230 CHEK1 phosphorylates RAD51 IEA Rattus norvegicus 456216 R-RNO-5686578 https://reactome.org/PathwayBrowser/#/R-RNO-5686578 Activated ATM phosphorylates ABL1 IEA Rattus norvegicus 456216 R-RNO-5686587 https://reactome.org/PathwayBrowser/#/R-RNO-5686587 ABL1 phosphorylates RAD52 IEA Rattus norvegicus 456216 R-RNO-5686704 https://reactome.org/PathwayBrowser/#/R-RNO-5686704 Activated ATM phosphorylates DCLRE1C IEA Rattus norvegicus 456216 R-RNO-5687086 https://reactome.org/PathwayBrowser/#/R-RNO-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Rattus norvegicus 456216 R-RNO-5687088 https://reactome.org/PathwayBrowser/#/R-RNO-5687088 PKA phosphorylates MAPKAPK5 IEA Rattus norvegicus 456216 R-RNO-5687090 https://reactome.org/PathwayBrowser/#/R-RNO-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Rattus norvegicus 456216 R-RNO-5687094 https://reactome.org/PathwayBrowser/#/R-RNO-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Rattus norvegicus 456216 R-RNO-5687101 https://reactome.org/PathwayBrowser/#/R-RNO-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Rattus norvegicus 456216 R-RNO-5687121 https://reactome.org/PathwayBrowser/#/R-RNO-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Rattus norvegicus 456216 R-RNO-5687183 https://reactome.org/PathwayBrowser/#/R-RNO-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Rattus norvegicus 456216 R-RNO-5690250 https://reactome.org/PathwayBrowser/#/R-RNO-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Rattus norvegicus 456216 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus 456216 R-RNO-5690996 https://reactome.org/PathwayBrowser/#/R-RNO-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Rattus norvegicus 456216 R-RNO-5692462 https://reactome.org/PathwayBrowser/#/R-RNO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Rattus norvegicus 456216 R-RNO-5692480 https://reactome.org/PathwayBrowser/#/R-RNO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Rattus norvegicus 456216 R-RNO-5692755 https://reactome.org/PathwayBrowser/#/R-RNO-5692755 CDK1 phosphorylates MAPK6 IEA Rattus norvegicus 456216 R-RNO-5692768 https://reactome.org/PathwayBrowser/#/R-RNO-5692768 MAPKAPK5 phosphorylates KALRN IEA Rattus norvegicus 456216 R-RNO-5692775 https://reactome.org/PathwayBrowser/#/R-RNO-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Rattus norvegicus 456216 R-RNO-5692779 https://reactome.org/PathwayBrowser/#/R-RNO-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Rattus norvegicus 456216 R-RNO-5693148 https://reactome.org/PathwayBrowser/#/R-RNO-5693148 BCKDK phosphorylates BCKDH IEA Rattus norvegicus 456216 R-RNO-5693536 https://reactome.org/PathwayBrowser/#/R-RNO-5693536 ATM phosphorylates MDC1 IEA Rattus norvegicus 456216 R-RNO-5693540 https://reactome.org/PathwayBrowser/#/R-RNO-5693540 MRN activates ATM IEA Rattus norvegicus 456216 R-RNO-5693549 https://reactome.org/PathwayBrowser/#/R-RNO-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Rattus norvegicus 456216 R-RNO-5693551 https://reactome.org/PathwayBrowser/#/R-RNO-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Rattus norvegicus 456216 R-RNO-5693575 https://reactome.org/PathwayBrowser/#/R-RNO-5693575 DNA-PKcs autophosphorylates IEA Rattus norvegicus 456216 R-RNO-5693598 https://reactome.org/PathwayBrowser/#/R-RNO-5693598 ATM phosphorylates NBN IEA Rattus norvegicus 456216 R-RNO-5693609 https://reactome.org/PathwayBrowser/#/R-RNO-5693609 ATM phosphorylates TP53 at S15 IEA Rattus norvegicus 456216 R-RNO-5694441 https://reactome.org/PathwayBrowser/#/R-RNO-5694441 CSNK1D phosphorylates SEC23 IEA Rattus norvegicus 456216 R-RNO-5696021 https://reactome.org/PathwayBrowser/#/R-RNO-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Rattus norvegicus 456216 R-RNO-5696074 https://reactome.org/PathwayBrowser/#/R-RNO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Rattus norvegicus 456216 R-RNO-5696839 https://reactome.org/PathwayBrowser/#/R-RNO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Rattus norvegicus 456216 R-RNO-622372 https://reactome.org/PathwayBrowser/#/R-RNO-622372 Phosphorylation of PLCgamma by Netrin-1 TAS Rattus norvegicus 456216 R-RNO-6782131 https://reactome.org/PathwayBrowser/#/R-RNO-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus 456216 R-RNO-6784006 https://reactome.org/PathwayBrowser/#/R-RNO-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Rattus norvegicus 456216 R-RNO-6784319 https://reactome.org/PathwayBrowser/#/R-RNO-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Rattus norvegicus 456216 R-RNO-6784324 https://reactome.org/PathwayBrowser/#/R-RNO-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Rattus norvegicus 456216 R-RNO-6786050 https://reactome.org/PathwayBrowser/#/R-RNO-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Rattus norvegicus 456216 R-RNO-6786095 https://reactome.org/PathwayBrowser/#/R-RNO-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Rattus norvegicus 456216 R-RNO-6786096 https://reactome.org/PathwayBrowser/#/R-RNO-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Rattus norvegicus 456216 R-RNO-6786245 https://reactome.org/PathwayBrowser/#/R-RNO-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Rattus norvegicus 456216 R-RNO-6787540 https://reactome.org/PathwayBrowser/#/R-RNO-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Rattus norvegicus 456216 R-RNO-6788392 https://reactome.org/PathwayBrowser/#/R-RNO-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Rattus norvegicus 456216 R-RNO-6788582 https://reactome.org/PathwayBrowser/#/R-RNO-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Rattus norvegicus 456216 R-RNO-6788798 https://reactome.org/PathwayBrowser/#/R-RNO-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 456216 R-RNO-6788810 https://reactome.org/PathwayBrowser/#/R-RNO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 456216 R-RNO-6788855 https://reactome.org/PathwayBrowser/#/R-RNO-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Rattus norvegicus 456216 R-RNO-6788867 https://reactome.org/PathwayBrowser/#/R-RNO-6788867 FN3K phosphorylates ketosamines IEA Rattus norvegicus 456216 R-RNO-6793661 https://reactome.org/PathwayBrowser/#/R-RNO-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Rattus norvegicus 456216 R-RNO-6795290 https://reactome.org/PathwayBrowser/#/R-RNO-6795290 TORC2 complex phosphorylates SGK1 IEA Rattus norvegicus 456216 R-RNO-6795460 https://reactome.org/PathwayBrowser/#/R-RNO-6795460 SGK1 phosphorylates MDM2 IEA Rattus norvegicus 456216 R-RNO-6795473 https://reactome.org/PathwayBrowser/#/R-RNO-6795473 PDPK1 phosphorylates SGK1 IEA Rattus norvegicus 456216 R-RNO-6797606 https://reactome.org/PathwayBrowser/#/R-RNO-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Rattus norvegicus 456216 R-RNO-6798174 https://reactome.org/PathwayBrowser/#/R-RNO-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Rattus norvegicus 456216 R-RNO-6798372 https://reactome.org/PathwayBrowser/#/R-RNO-6798372 ATM phosphorylates DYRK2 IEA Rattus norvegicus 456216 R-RNO-6798374 https://reactome.org/PathwayBrowser/#/R-RNO-6798374 DYRK2 phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6799097 https://reactome.org/PathwayBrowser/#/R-RNO-6799097 ATM phosphorylates ZNF420 IEA Rattus norvegicus 456216 R-RNO-6799246 https://reactome.org/PathwayBrowser/#/R-RNO-6799246 CHEK1 phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6799332 https://reactome.org/PathwayBrowser/#/R-RNO-6799332 ATR phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6799495 https://reactome.org/PathwayBrowser/#/R-RNO-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Rattus norvegicus 456216 R-RNO-6800490 https://reactome.org/PathwayBrowser/#/R-RNO-6800490 ATM phosphorylates PIDD1 IEA Rattus norvegicus 456216 R-RNO-6801342 https://reactome.org/PathwayBrowser/#/R-RNO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Rattus norvegicus 456216 R-RNO-6801456 https://reactome.org/PathwayBrowser/#/R-RNO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Rattus norvegicus 456216 R-RNO-6801666 https://reactome.org/PathwayBrowser/#/R-RNO-6801666 PLK2 phosphorylates CENPJ IEA Rattus norvegicus 456216 R-RNO-6801675 https://reactome.org/PathwayBrowser/#/R-RNO-6801675 PLK2 phosphorylates NPM1 IEA Rattus norvegicus 456216 R-RNO-6802973 https://reactome.org/PathwayBrowser/#/R-RNO-6802973 PLK3 phosphorylates CDC25C IEA Rattus norvegicus 456216 R-RNO-6803545 https://reactome.org/PathwayBrowser/#/R-RNO-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Rattus norvegicus 456216 R-RNO-6803771 https://reactome.org/PathwayBrowser/#/R-RNO-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Rattus norvegicus 456216 R-RNO-6804266 https://reactome.org/PathwayBrowser/#/R-RNO-6804266 CHEK2 phosphorylates TTC5 IEA Rattus norvegicus 456216 R-RNO-6804276 https://reactome.org/PathwayBrowser/#/R-RNO-6804276 ATM phosphorylates TTC5 IEA Rattus norvegicus 456216 R-RNO-6804955 https://reactome.org/PathwayBrowser/#/R-RNO-6804955 ATM phosphorylates MDM2 IEA Rattus norvegicus 456216 R-RNO-6805059 https://reactome.org/PathwayBrowser/#/R-RNO-6805059 CK2:FACT phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6805103 https://reactome.org/PathwayBrowser/#/R-RNO-6805103 AURKA phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6805109 https://reactome.org/PathwayBrowser/#/R-RNO-6805109 CDK2 phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6805126 https://reactome.org/PathwayBrowser/#/R-RNO-6805126 AURKB phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6805276 https://reactome.org/PathwayBrowser/#/R-RNO-6805276 CDK5 phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6805285 https://reactome.org/PathwayBrowser/#/R-RNO-6805285 PLK3 phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6805399 https://reactome.org/PathwayBrowser/#/R-RNO-6805399 TAF1 phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6805470 https://reactome.org/PathwayBrowser/#/R-RNO-6805470 AMPK phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6805479 https://reactome.org/PathwayBrowser/#/R-RNO-6805479 TP53RK phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-6805507 https://reactome.org/PathwayBrowser/#/R-RNO-6805507 APAF1 binds AVEN IEA Rattus norvegicus 456216 R-RNO-6805640 https://reactome.org/PathwayBrowser/#/R-RNO-6805640 AKT phosphorylates KAT6A IEA Rattus norvegicus 456216 R-RNO-6805785 https://reactome.org/PathwayBrowser/#/R-RNO-6805785 AKT phosphorylates PHF20 IEA Rattus norvegicus 456216 R-RNO-6806877 https://reactome.org/PathwayBrowser/#/R-RNO-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Rattus norvegicus 456216 R-RNO-6806967 https://reactome.org/PathwayBrowser/#/R-RNO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Rattus norvegicus 456216 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 456216 R-RNO-6807868 https://reactome.org/PathwayBrowser/#/R-RNO-6807868 GBF1 stimulates ARF nucleotide exchange IEA Rattus norvegicus 456216 R-RNO-6810233 https://reactome.org/PathwayBrowser/#/R-RNO-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Rattus norvegicus 456216 R-RNO-6810472 https://reactome.org/PathwayBrowser/#/R-RNO-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Rattus norvegicus 456216 R-RNO-6811454 https://reactome.org/PathwayBrowser/#/R-RNO-6811454 MAPKs phosphorylate PP2A IEA Rattus norvegicus 456216 R-RNO-6811522 https://reactome.org/PathwayBrowser/#/R-RNO-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Rattus norvegicus 456216 R-RNO-6814119 https://reactome.org/PathwayBrowser/#/R-RNO-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Rattus norvegicus 456216 R-RNO-6814120 https://reactome.org/PathwayBrowser/#/R-RNO-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Rattus norvegicus 456216 R-RNO-6814121 https://reactome.org/PathwayBrowser/#/R-RNO-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Rattus norvegicus 456216 R-RNO-6814124 https://reactome.org/PathwayBrowser/#/R-RNO-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Rattus norvegicus 456216 R-RNO-6814409 https://reactome.org/PathwayBrowser/#/R-RNO-6814409 CK2 phosphorylates PDCL IEA Rattus norvegicus 456216 R-RNO-6814683 https://reactome.org/PathwayBrowser/#/R-RNO-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Rattus norvegicus 456216 R-RNO-68944 https://reactome.org/PathwayBrowser/#/R-RNO-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Rattus norvegicus 456216 R-RNO-68954 https://reactome.org/PathwayBrowser/#/R-RNO-68954 Mcm2-7 is phosphorylated by DDK IEA Rattus norvegicus 456216 R-RNO-69005 https://reactome.org/PathwayBrowser/#/R-RNO-69005 Cdc6 protein is phosphorylated by CDK IEA Rattus norvegicus 456216 R-RNO-69063 https://reactome.org/PathwayBrowser/#/R-RNO-69063 Loading of PCNA - Sliding Clamp Formation IEA Rattus norvegicus 456216 R-RNO-69195 https://reactome.org/PathwayBrowser/#/R-RNO-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Rattus norvegicus 456216 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 456216 R-RNO-69604 https://reactome.org/PathwayBrowser/#/R-RNO-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Rattus norvegicus 456216 R-RNO-69608 https://reactome.org/PathwayBrowser/#/R-RNO-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Rattus norvegicus 456216 R-RNO-69685 https://reactome.org/PathwayBrowser/#/R-RNO-69685 CHEK2 phosphorylates TP53 IEA Rattus norvegicus 456216 R-RNO-69891 https://reactome.org/PathwayBrowser/#/R-RNO-69891 Phosphorylation and activation of CHEK2 by ATM IEA Rattus norvegicus 456216 R-RNO-70333 https://reactome.org/PathwayBrowser/#/R-RNO-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Rattus norvegicus 456216 R-RNO-70349 https://reactome.org/PathwayBrowser/#/R-RNO-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 456216 R-RNO-70355 https://reactome.org/PathwayBrowser/#/R-RNO-70355 GALK1 phosphorylates Gal to Gal1P IEA Rattus norvegicus 456216 R-RNO-70420 https://reactome.org/PathwayBrowser/#/R-RNO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Rattus norvegicus 456216 R-RNO-70467 https://reactome.org/PathwayBrowser/#/R-RNO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Rattus norvegicus 456216 R-RNO-70486 https://reactome.org/PathwayBrowser/#/R-RNO-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Rattus norvegicus 456216 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 456216 R-RNO-70555 https://reactome.org/PathwayBrowser/#/R-RNO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Rattus norvegicus 456216 R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Rattus norvegicus 456216 R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Rattus norvegicus 456216 R-RNO-70606 https://reactome.org/PathwayBrowser/#/R-RNO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Rattus norvegicus 456216 R-RNO-70773 https://reactome.org/PathwayBrowser/#/R-RNO-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Rattus norvegicus 456216 R-RNO-70967 https://reactome.org/PathwayBrowser/#/R-RNO-70967 IDH3 complex decarboxylates isocitrate IEA Rattus norvegicus 456216 R-RNO-70997 https://reactome.org/PathwayBrowser/#/R-RNO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Rattus norvegicus 456216 R-RNO-71031 https://reactome.org/PathwayBrowser/#/R-RNO-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Rattus norvegicus 456216 R-RNO-71401 https://reactome.org/PathwayBrowser/#/R-RNO-71401 OGDH dimer decarboxylates 2-OG IEA Rattus norvegicus 456216 R-RNO-71541 https://reactome.org/PathwayBrowser/#/R-RNO-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Rattus norvegicus 456216 R-RNO-71588 https://reactome.org/PathwayBrowser/#/R-RNO-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Rattus norvegicus 456216 R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 456216 R-RNO-71802 https://reactome.org/PathwayBrowser/#/R-RNO-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Rattus norvegicus 456216 R-RNO-71850 https://reactome.org/PathwayBrowser/#/R-RNO-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Rattus norvegicus 456216 R-RNO-72621 https://reactome.org/PathwayBrowser/#/R-RNO-72621 Ribosomal scanning IEA Rattus norvegicus 456216 R-RNO-727819 https://reactome.org/PathwayBrowser/#/R-RNO-727819 TAK1 phosphorylates MKK6 IEA Rattus norvegicus 456216 R-RNO-73548 https://reactome.org/PathwayBrowser/#/R-RNO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Rattus norvegicus 456216 R-RNO-73577 https://reactome.org/PathwayBrowser/#/R-RNO-73577 CAD hexamer transforms L-Gln to CAP IEA Rattus norvegicus 456216 R-RNO-73598 https://reactome.org/PathwayBrowser/#/R-RNO-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Rattus norvegicus 456216 R-RNO-73599 https://reactome.org/PathwayBrowser/#/R-RNO-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Rattus norvegicus 456216 R-RNO-73632 https://reactome.org/PathwayBrowser/#/R-RNO-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Rattus norvegicus 456216 R-RNO-73635 https://reactome.org/PathwayBrowser/#/R-RNO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Rattus norvegicus 456216 R-RNO-73647 https://reactome.org/PathwayBrowser/#/R-RNO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Rattus norvegicus 456216 R-RNO-73722 https://reactome.org/PathwayBrowser/#/R-RNO-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Rattus norvegicus 456216 R-RNO-73788 https://reactome.org/PathwayBrowser/#/R-RNO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Rattus norvegicus 456216 R-RNO-73805 https://reactome.org/PathwayBrowser/#/R-RNO-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Rattus norvegicus 456216 R-RNO-73810 https://reactome.org/PathwayBrowser/#/R-RNO-73810 FGAM + ATP => AIR + ADP + Pi IEA Rattus norvegicus 456216 R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 456216 R-RNO-73814 https://reactome.org/PathwayBrowser/#/R-RNO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Rattus norvegicus 456216 R-RNO-74207 https://reactome.org/PathwayBrowser/#/R-RNO-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Rattus norvegicus 456216 R-RNO-74220 https://reactome.org/PathwayBrowser/#/R-RNO-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Rattus norvegicus 456216 R-RNO-74711 https://reactome.org/PathwayBrowser/#/R-RNO-74711 Phosphorylation of IRS IEA Rattus norvegicus 456216 R-RNO-74715 https://reactome.org/PathwayBrowser/#/R-RNO-74715 Autophosphorylation of insulin receptor IEA Rattus norvegicus 456216 R-RNO-74742 https://reactome.org/PathwayBrowser/#/R-RNO-74742 Phosphorylation of SHC1 IEA Rattus norvegicus 456216 R-RNO-75010 https://reactome.org/PathwayBrowser/#/R-RNO-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Rattus norvegicus 456216 R-RNO-75125 https://reactome.org/PathwayBrowser/#/R-RNO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Rattus norvegicus 456216 R-RNO-75126 https://reactome.org/PathwayBrowser/#/R-RNO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Rattus norvegicus 456216 R-RNO-75809 https://reactome.org/PathwayBrowser/#/R-RNO-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Rattus norvegicus 456216 R-RNO-75848 https://reactome.org/PathwayBrowser/#/R-RNO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Rattus norvegicus 456216 R-RNO-75851 https://reactome.org/PathwayBrowser/#/R-RNO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 456216 R-RNO-75887 https://reactome.org/PathwayBrowser/#/R-RNO-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Rattus norvegicus 456216 R-RNO-75949 https://reactome.org/PathwayBrowser/#/R-RNO-75949 RNA Polymerase II Promoter Opening: First Transition IEA Rattus norvegicus 456216 R-RNO-77071 https://reactome.org/PathwayBrowser/#/R-RNO-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Rattus norvegicus 456216 R-RNO-873918 https://reactome.org/PathwayBrowser/#/R-RNO-873918 Transphosphorylation of JAK1 IEA Rattus norvegicus 456216 R-RNO-873919 https://reactome.org/PathwayBrowser/#/R-RNO-873919 Phosphorylation of JAK2 IEA Rattus norvegicus 456216 R-RNO-873922 https://reactome.org/PathwayBrowser/#/R-RNO-873922 Phosphorylation of STAT1 by JAK kinases IEA Rattus norvegicus 456216 R-RNO-873924 https://reactome.org/PathwayBrowser/#/R-RNO-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Rattus norvegicus 456216 R-RNO-879907 https://reactome.org/PathwayBrowser/#/R-RNO-879907 Tyrosine kinases phosphorylate the receptor IEA Rattus norvegicus 456216 R-RNO-879909 https://reactome.org/PathwayBrowser/#/R-RNO-879909 Activation of STAT5a/b by JAK2 IEA Rattus norvegicus 456216 R-RNO-879910 https://reactome.org/PathwayBrowser/#/R-RNO-879910 JAK2 is phosphorylated, activated IEA Rattus norvegicus 456216 R-RNO-8847638 https://reactome.org/PathwayBrowser/#/R-RNO-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Rattus norvegicus 456216 R-RNO-8847977 https://reactome.org/PathwayBrowser/#/R-RNO-8847977 FRK phosphorylates PTEN IEA Rattus norvegicus 456216 R-RNO-8848005 https://reactome.org/PathwayBrowser/#/R-RNO-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Rattus norvegicus 456216 R-RNO-8848053 https://reactome.org/PathwayBrowser/#/R-RNO-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Rattus norvegicus 456216 R-RNO-8848077 https://reactome.org/PathwayBrowser/#/R-RNO-8848077 PTK6 phosphorylates STAP2 IEA Rattus norvegicus 456216 R-RNO-8848124 https://reactome.org/PathwayBrowser/#/R-RNO-8848124 PTK6 phosphorylates STAT3 IEA Rattus norvegicus 456216 R-RNO-8848436 https://reactome.org/PathwayBrowser/#/R-RNO-8848436 PTK6 phosphorylates CDKN1B IEA Rattus norvegicus 456216 R-RNO-8848606 https://reactome.org/PathwayBrowser/#/R-RNO-8848606 PTK6 phosphorylates PXN IEA Rattus norvegicus 456216 R-RNO-8848726 https://reactome.org/PathwayBrowser/#/R-RNO-8848726 PTK6 phosphorylates BCAR1 IEA Rattus norvegicus 456216 R-RNO-8848758 https://reactome.org/PathwayBrowser/#/R-RNO-8848758 PTK6 phosphorylates AKT1 IEA Rattus norvegicus 456216 R-RNO-8848776 https://reactome.org/PathwayBrowser/#/R-RNO-8848776 PTK6 phosphorylates DOK1 IEA Rattus norvegicus 456216 R-RNO-8848818 https://reactome.org/PathwayBrowser/#/R-RNO-8848818 PTK6 phosphorylates CBL IEA Rattus norvegicus 456216 R-RNO-8848873 https://reactome.org/PathwayBrowser/#/R-RNO-8848873 PTK6 phosphorylates ARAP1 IEA Rattus norvegicus 456216 R-RNO-8848975 https://reactome.org/PathwayBrowser/#/R-RNO-8848975 PTK6 phosphorylates KHDRBS1 IEA Rattus norvegicus 456216 R-RNO-8849032 https://reactome.org/PathwayBrowser/#/R-RNO-8849032 PTK6 phosphorylates KHDRBS2 IEA Rattus norvegicus 456216 R-RNO-8849042 https://reactome.org/PathwayBrowser/#/R-RNO-8849042 PTK6 phosphorylates KHDRBS3 IEA Rattus norvegicus 456216 R-RNO-8849068 https://reactome.org/PathwayBrowser/#/R-RNO-8849068 PTK6 phosphorylates ARHGAP35 IEA Rattus norvegicus 456216 R-RNO-8849102 https://reactome.org/PathwayBrowser/#/R-RNO-8849102 SRMS phosphorylates PTK6 IEA Rattus norvegicus 456216 R-RNO-8849353 https://reactome.org/PathwayBrowser/#/R-RNO-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Rattus norvegicus 456216 R-RNO-8849463 https://reactome.org/PathwayBrowser/#/R-RNO-8849463 PTK6 phosphorylates SFPQ IEA Rattus norvegicus 456216 R-RNO-8850527 https://reactome.org/PathwayBrowser/#/R-RNO-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Rattus norvegicus 456216 R-RNO-8850529 https://reactome.org/PathwayBrowser/#/R-RNO-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Rattus norvegicus 456216 R-RNO-8850534 https://reactome.org/PathwayBrowser/#/R-RNO-8850534 PDCL promotes G-protein beta 5 folding IEA Rattus norvegicus 456216 R-RNO-8850539 https://reactome.org/PathwayBrowser/#/R-RNO-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Rattus norvegicus 456216 R-RNO-8850945 https://reactome.org/PathwayBrowser/#/R-RNO-8850945 Casein kinase II phosphorylates PTEN IEA Rattus norvegicus 456216 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 456216 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 456216 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 456216 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 456216 R-RNO-8851797 https://reactome.org/PathwayBrowser/#/R-RNO-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Rattus norvegicus 456216 R-RNO-8851890 https://reactome.org/PathwayBrowser/#/R-RNO-8851890 MET phosphorylates SHC1-2 IEA Rattus norvegicus 456216 R-RNO-8851933 https://reactome.org/PathwayBrowser/#/R-RNO-8851933 MET phosphorylates GAB1 IEA Rattus norvegicus 456216 R-RNO-8852019 https://reactome.org/PathwayBrowser/#/R-RNO-8852019 MET bound PI3K generates PIP3 IEA Rattus norvegicus 456216 R-RNO-8852306 https://reactome.org/PathwayBrowser/#/R-RNO-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Rattus norvegicus 456216 R-RNO-8852317 https://reactome.org/PathwayBrowser/#/R-RNO-8852317 PLK1 phosphorylates GTSE1 IEA Rattus norvegicus 456216 R-RNO-8852552 https://reactome.org/PathwayBrowser/#/R-RNO-8852552 MST1R autophosphorylates IEA Rattus norvegicus 456216 R-RNO-8853419 https://reactome.org/PathwayBrowser/#/R-RNO-8853419 TPX2 promotes AURKA autophosphorylation IEA Rattus norvegicus 456216 R-RNO-8853444 https://reactome.org/PathwayBrowser/#/R-RNO-8853444 AURKA phosphorylates PHLDA1 IEA Rattus norvegicus 456216 R-RNO-8853774 https://reactome.org/PathwayBrowser/#/R-RNO-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Rattus norvegicus 456216 R-RNO-8853792 https://reactome.org/PathwayBrowser/#/R-RNO-8853792 RET tyrosine phosphorylation IEA Rattus norvegicus 456216 R-RNO-8854908 https://reactome.org/PathwayBrowser/#/R-RNO-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Rattus norvegicus 456216 R-RNO-8855237 https://reactome.org/PathwayBrowser/#/R-RNO-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Rattus norvegicus 456216 R-RNO-8856813 https://reactome.org/PathwayBrowser/#/R-RNO-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Rattus norvegicus 456216 R-RNO-8857555 https://reactome.org/PathwayBrowser/#/R-RNO-8857555 EGFR phosphorylates GPNMB IEA Rattus norvegicus 456216 R-RNO-8857577 https://reactome.org/PathwayBrowser/#/R-RNO-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Rattus norvegicus 456216 R-RNO-8857583 https://reactome.org/PathwayBrowser/#/R-RNO-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Rattus norvegicus 456216 R-RNO-8857925 https://reactome.org/PathwayBrowser/#/R-RNO-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Rattus norvegicus 456216 R-RNO-8865774 https://reactome.org/PathwayBrowser/#/R-RNO-8865774 TTLLs polyglutamylate tubulin IEA Rattus norvegicus 456216 R-RNO-8866268 https://reactome.org/PathwayBrowser/#/R-RNO-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Rattus norvegicus 456216 R-RNO-8866542 https://reactome.org/PathwayBrowser/#/R-RNO-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Rattus norvegicus 456216 R-RNO-8867041 https://reactome.org/PathwayBrowser/#/R-RNO-8867041 EGFR phosphorylates EPS15 IEA Rattus norvegicus 456216 R-RNO-8867370 https://reactome.org/PathwayBrowser/#/R-RNO-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Rattus norvegicus 456216 R-RNO-8868066 https://reactome.org/PathwayBrowser/#/R-RNO-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Rattus norvegicus 456216 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 456216 R-RNO-8868118 https://reactome.org/PathwayBrowser/#/R-RNO-8868118 MAPK12 phosphorylates PTPN3 IEA Rattus norvegicus 456216 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 456216 R-RNO-8869606 https://reactome.org/PathwayBrowser/#/R-RNO-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Rattus norvegicus 456216 R-RNO-8869633 https://reactome.org/PathwayBrowser/#/R-RNO-8869633 NMRK1 phosphorylates NR to yield NMN IEA Rattus norvegicus 456216 R-RNO-8871373 https://reactome.org/PathwayBrowser/#/R-RNO-8871373 BMX phosphorylates RUFY1 IEA Rattus norvegicus 456216 R-RNO-8873929 https://reactome.org/PathwayBrowser/#/R-RNO-8873929 Casein kinase II phosphorylates STARD10 IEA Rattus norvegicus 456216 R-RNO-8874078 https://reactome.org/PathwayBrowser/#/R-RNO-8874078 PTK2 autophosphorylates IEA Rattus norvegicus 456216 R-RNO-8874080 https://reactome.org/PathwayBrowser/#/R-RNO-8874080 SRC phosphorylates PTK2 IEA Rattus norvegicus 456216 R-RNO-8874082 https://reactome.org/PathwayBrowser/#/R-RNO-8874082 MET phosphorylates PTK2 IEA Rattus norvegicus 456216 R-RNO-8875451 https://reactome.org/PathwayBrowser/#/R-RNO-8875451 MET phosphorylates CBL IEA Rattus norvegicus 456216 R-RNO-8875817 https://reactome.org/PathwayBrowser/#/R-RNO-8875817 MET phosphorylates STAT3 IEA Rattus norvegicus 456216 R-RNO-8876446 https://reactome.org/PathwayBrowser/#/R-RNO-8876446 p-ULK1 phosphorylates DENND3 IEA Rattus norvegicus 456216 R-RNO-8876889 https://reactome.org/PathwayBrowser/#/R-RNO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 456216 R-RNO-8877691 https://reactome.org/PathwayBrowser/#/R-RNO-8877691 MAP2K6 phosphorylates PIP4K2B IEA Rattus norvegicus 456216 R-RNO-8931653 https://reactome.org/PathwayBrowser/#/R-RNO-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Rattus norvegicus 456216 R-RNO-8932373 https://reactome.org/PathwayBrowser/#/R-RNO-8932373 PKC phosphorylates Nrf2 TAS Rattus norvegicus 456216 R-RNO-8933446 https://reactome.org/PathwayBrowser/#/R-RNO-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Rattus norvegicus 456216 R-RNO-8934446 https://reactome.org/PathwayBrowser/#/R-RNO-8934446 Activated PKC phosphorylates SHC1 IEA Rattus norvegicus 456216 R-RNO-8937807 https://reactome.org/PathwayBrowser/#/R-RNO-8937807 SRC phosphorylates RUNX3 IEA Rattus norvegicus 456216 R-RNO-8937915 https://reactome.org/PathwayBrowser/#/R-RNO-8937915 Src,Yes1 phosphorylate Yap1 TAS Rattus norvegicus 456216 R-RNO-8940100 https://reactome.org/PathwayBrowser/#/R-RNO-8940100 CDK1 phosphorylates VCPIP1 IEA Rattus norvegicus 456216 R-RNO-8942575 https://reactome.org/PathwayBrowser/#/R-RNO-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Rattus norvegicus 456216 R-RNO-8942607 https://reactome.org/PathwayBrowser/#/R-RNO-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Rattus norvegicus 456216 R-RNO-8942836 https://reactome.org/PathwayBrowser/#/R-RNO-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Rattus norvegicus 456216 R-RNO-8944454 https://reactome.org/PathwayBrowser/#/R-RNO-8944454 mTORC1 phosphorylates MAF1 IEA Rattus norvegicus 456216 R-RNO-8948039 https://reactome.org/PathwayBrowser/#/R-RNO-8948039 FUNDC1 is phosphorylated by CK2 IEA Rattus norvegicus 456216 R-RNO-8948143 https://reactome.org/PathwayBrowser/#/R-RNO-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Rattus norvegicus 456216 R-RNO-8948146 https://reactome.org/PathwayBrowser/#/R-RNO-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Rattus norvegicus 456216 R-RNO-8948757 https://reactome.org/PathwayBrowser/#/R-RNO-8948757 AKT phosphorylates MKRN1 IEA Rattus norvegicus 456216 R-RNO-8950269 https://reactome.org/PathwayBrowser/#/R-RNO-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Rattus norvegicus 456216 R-RNO-8950340 https://reactome.org/PathwayBrowser/#/R-RNO-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Rattus norvegicus 456216 R-RNO-8950405 https://reactome.org/PathwayBrowser/#/R-RNO-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Rattus norvegicus 456216 R-RNO-8950423 https://reactome.org/PathwayBrowser/#/R-RNO-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Rattus norvegicus 456216 R-RNO-8950453 https://reactome.org/PathwayBrowser/#/R-RNO-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Rattus norvegicus 456216 R-RNO-8950485 https://reactome.org/PathwayBrowser/#/R-RNO-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Rattus norvegicus 456216 R-RNO-8950537 https://reactome.org/PathwayBrowser/#/R-RNO-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Rattus norvegicus 456216 R-RNO-8950757 https://reactome.org/PathwayBrowser/#/R-RNO-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Rattus norvegicus 456216 R-RNO-8952289 https://reactome.org/PathwayBrowser/#/R-RNO-8952289 FAM20C phosphorylates FAM20C substrates IEA Rattus norvegicus 456216 R-RNO-8954327 https://reactome.org/PathwayBrowser/#/R-RNO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Rattus norvegicus 456216 R-RNO-8955030 https://reactome.org/PathwayBrowser/#/R-RNO-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 456216 R-RNO-8955844 https://reactome.org/PathwayBrowser/#/R-RNO-8955844 RBKS phosphorylates ribose to R5P IEA Rattus norvegicus 456216 R-RNO-8956659 https://reactome.org/PathwayBrowser/#/R-RNO-8956659 ABL1 phosphorylates YAP1 IEA Rattus norvegicus 456216 R-RNO-8959719 https://reactome.org/PathwayBrowser/#/R-RNO-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Rattus norvegicus 456216 R-RNO-8964242 https://reactome.org/PathwayBrowser/#/R-RNO-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Rattus norvegicus 456216 R-RNO-8982163 https://reactome.org/PathwayBrowser/#/R-RNO-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Rattus norvegicus 456216 R-RNO-8983059 https://reactome.org/PathwayBrowser/#/R-RNO-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Rattus norvegicus 456216 R-RNO-8983063 https://reactome.org/PathwayBrowser/#/R-RNO-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Rattus norvegicus 456216 R-RNO-8983300 https://reactome.org/PathwayBrowser/#/R-RNO-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Rattus norvegicus 456216 R-RNO-8983371 https://reactome.org/PathwayBrowser/#/R-RNO-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Rattus norvegicus 456216 R-RNO-8983834 https://reactome.org/PathwayBrowser/#/R-RNO-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Rattus norvegicus 456216 R-RNO-8983835 https://reactome.org/PathwayBrowser/#/R-RNO-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Rattus norvegicus 456216 R-RNO-8983870 https://reactome.org/PathwayBrowser/#/R-RNO-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Rattus norvegicus 456216 R-RNO-8983872 https://reactome.org/PathwayBrowser/#/R-RNO-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Rattus norvegicus 456216 R-RNO-8984012 https://reactome.org/PathwayBrowser/#/R-RNO-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Rattus norvegicus 456216 R-RNO-8984014 https://reactome.org/PathwayBrowser/#/R-RNO-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Rattus norvegicus 456216 R-RNO-8985914 https://reactome.org/PathwayBrowser/#/R-RNO-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Rattus norvegicus 456216 R-RNO-8985973 https://reactome.org/PathwayBrowser/#/R-RNO-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Rattus norvegicus 456216 R-RNO-8985988 https://reactome.org/PathwayBrowser/#/R-RNO-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Rattus norvegicus 456216 R-RNO-8986985 https://reactome.org/PathwayBrowser/#/R-RNO-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Rattus norvegicus 456216 R-RNO-8986994 https://reactome.org/PathwayBrowser/#/R-RNO-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Rattus norvegicus 456216 R-RNO-8986995 https://reactome.org/PathwayBrowser/#/R-RNO-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Rattus norvegicus 456216 R-RNO-8987012 https://reactome.org/PathwayBrowser/#/R-RNO-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Rattus norvegicus 456216 R-RNO-8987040 https://reactome.org/PathwayBrowser/#/R-RNO-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Rattus norvegicus 456216 R-RNO-8987042 https://reactome.org/PathwayBrowser/#/R-RNO-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Rattus norvegicus 456216 R-RNO-8987070 https://reactome.org/PathwayBrowser/#/R-RNO-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Rattus norvegicus 456216 R-RNO-8987084 https://reactome.org/PathwayBrowser/#/R-RNO-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Rattus norvegicus 456216 R-RNO-8987096 https://reactome.org/PathwayBrowser/#/R-RNO-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Rattus norvegicus 456216 R-RNO-8987129 https://reactome.org/PathwayBrowser/#/R-RNO-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Rattus norvegicus 456216 R-RNO-8987141 https://reactome.org/PathwayBrowser/#/R-RNO-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Rattus norvegicus 456216 R-RNO-8987150 https://reactome.org/PathwayBrowser/#/R-RNO-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Rattus norvegicus 456216 R-RNO-8987179 https://reactome.org/PathwayBrowser/#/R-RNO-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Rattus norvegicus 456216 R-RNO-8987202 https://reactome.org/PathwayBrowser/#/R-RNO-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Rattus norvegicus 456216 R-RNO-8987255 https://reactome.org/PathwayBrowser/#/R-RNO-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Rattus norvegicus 456216 R-RNO-9006850 https://reactome.org/PathwayBrowser/#/R-RNO-9006850 IL21 receptor JAK phosphorylation IEA Rattus norvegicus 456216 R-RNO-9006870 https://reactome.org/PathwayBrowser/#/R-RNO-9006870 IL21 receptor STAT phosphorylation IEA Rattus norvegicus 456216 R-RNO-9007539 https://reactome.org/PathwayBrowser/#/R-RNO-9007539 CHEK1 phosphorylates E2F6 IEA Rattus norvegicus 456216 R-RNO-9008043 https://reactome.org/PathwayBrowser/#/R-RNO-9008043 MAPK8 phosphorylation IEA Rattus norvegicus 456216 R-RNO-9008684 https://reactome.org/PathwayBrowser/#/R-RNO-9008684 TBK1 phosphorylation IEA Rattus norvegicus 456216 R-RNO-9009072 https://reactome.org/PathwayBrowser/#/R-RNO-9009072 STAT3 phosphorylation IEA Rattus norvegicus 456216 R-RNO-9012319 https://reactome.org/PathwayBrowser/#/R-RNO-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Rattus norvegicus 456216 R-RNO-9018572 https://reactome.org/PathwayBrowser/#/R-RNO-9018572 EGFR phosphorylates NOTCH3 IEA Rattus norvegicus 456216 R-RNO-9021357 https://reactome.org/PathwayBrowser/#/R-RNO-9021357 PRKCI phosphorylates ELF3 IEA Rattus norvegicus 456216 R-RNO-9021609 https://reactome.org/PathwayBrowser/#/R-RNO-9021609 ESR-associated SRC autophosphorylates IEA Rattus norvegicus 456216 R-RNO-9021627 https://reactome.org/PathwayBrowser/#/R-RNO-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 456216 R-RNO-9027272 https://reactome.org/PathwayBrowser/#/R-RNO-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Rattus norvegicus 456216 R-RNO-9027273 https://reactome.org/PathwayBrowser/#/R-RNO-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Rattus norvegicus 456216 R-RNO-9030485 https://reactome.org/PathwayBrowser/#/R-RNO-9030485 Activated Ntrk2 phosphorylates Shc1 TAS Rattus norvegicus 456216 R-RNO-9032568 https://reactome.org/PathwayBrowser/#/R-RNO-9032568 Ntrk2-bound Fyn autophosphorylates TAS Rattus norvegicus 456216 R-RNO-9032619 https://reactome.org/PathwayBrowser/#/R-RNO-9032619 Fyn-mediated phosphorylation of Grin2b TAS Rattus norvegicus 456216 R-RNO-9033499 https://reactome.org/PathwayBrowser/#/R-RNO-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Rattus norvegicus 456216 R-RNO-9034714 https://reactome.org/PathwayBrowser/#/R-RNO-9034714 NTRK3 dimers trans-autophosphorylate IEA Rattus norvegicus 456216 R-RNO-9037056 https://reactome.org/PathwayBrowser/#/R-RNO-9037056 Src phosphorylates Ntrk2 TAS Rattus norvegicus 456216 R-RNO-9038161 https://reactome.org/PathwayBrowser/#/R-RNO-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Rattus norvegicus 456216 R-RNO-909552 https://reactome.org/PathwayBrowser/#/R-RNO-909552 Phosphorylation of STAT1 at Ser727 IEA Rattus norvegicus 456216 R-RNO-909718 https://reactome.org/PathwayBrowser/#/R-RNO-909718 Formation of p-STAT1 homodimer IEA Rattus norvegicus 456216 R-RNO-909729 https://reactome.org/PathwayBrowser/#/R-RNO-909729 Activation of JAK kinases IEA Rattus norvegicus 456216 R-RNO-909730 https://reactome.org/PathwayBrowser/#/R-RNO-909730 Phosphorylation of INFAR1 by TYK2 IEA Rattus norvegicus 456216 R-RNO-909732 https://reactome.org/PathwayBrowser/#/R-RNO-909732 Phosphorylation of STAT2 IEA Rattus norvegicus 456216 R-RNO-912527 https://reactome.org/PathwayBrowser/#/R-RNO-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Rattus norvegicus 456216 R-RNO-913996 https://reactome.org/PathwayBrowser/#/R-RNO-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Rattus norvegicus 456216 R-RNO-917693 https://reactome.org/PathwayBrowser/#/R-RNO-917693 ESCRT Disassembly IEA Rattus norvegicus 456216 R-RNO-917841 https://reactome.org/PathwayBrowser/#/R-RNO-917841 Acidification of Tf:TfR1 containing endosome IEA Rattus norvegicus 456216 R-RNO-917979 https://reactome.org/PathwayBrowser/#/R-RNO-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-927889 https://reactome.org/PathwayBrowser/#/R-RNO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Rattus norvegicus 456216 R-RNO-934559 https://reactome.org/PathwayBrowser/#/R-RNO-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Rattus norvegicus 456216 R-RNO-936802 https://reactome.org/PathwayBrowser/#/R-RNO-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Rattus norvegicus 456216 R-RNO-936883 https://reactome.org/PathwayBrowser/#/R-RNO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Rattus norvegicus 456216 R-RNO-936895 https://reactome.org/PathwayBrowser/#/R-RNO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Rattus norvegicus 456216 R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 456216 R-RNO-936951 https://reactome.org/PathwayBrowser/#/R-RNO-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Rattus norvegicus 456216 R-RNO-936991 https://reactome.org/PathwayBrowser/#/R-RNO-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Rattus norvegicus 456216 R-RNO-937034 https://reactome.org/PathwayBrowser/#/R-RNO-937034 IRAK1 phosphorylates Pellino IEA Rattus norvegicus 456216 R-RNO-937311 https://reactome.org/PathwayBrowser/#/R-RNO-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 456216 R-RNO-939763 https://reactome.org/PathwayBrowser/#/R-RNO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Rattus norvegicus 456216 R-RNO-947591 https://reactome.org/PathwayBrowser/#/R-RNO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Rattus norvegicus 456216 R-RNO-9603420 https://reactome.org/PathwayBrowser/#/R-RNO-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Rattus norvegicus 456216 R-RNO-9604328 https://reactome.org/PathwayBrowser/#/R-RNO-9604328 AKT1 phosphorylates NOTCH4 IEA Rattus norvegicus 456216 R-RNO-9606884 https://reactome.org/PathwayBrowser/#/R-RNO-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Rattus norvegicus 456216 R-RNO-9610153 https://reactome.org/PathwayBrowser/#/R-RNO-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Rattus norvegicus 456216 R-RNO-9610156 https://reactome.org/PathwayBrowser/#/R-RNO-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Rattus norvegicus 456216 R-RNO-9610163 https://reactome.org/PathwayBrowser/#/R-RNO-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Rattus norvegicus 456216 R-RNO-9612145 https://reactome.org/PathwayBrowser/#/R-RNO-9612145 Src phosphorylates GluN2 (Grin2) subunits of NMDARs TAS Rattus norvegicus 456216 R-RNO-9612501 https://reactome.org/PathwayBrowser/#/R-RNO-9612501 SGK phosphorylates CREB1 IEA Rattus norvegicus 456216 R-RNO-9612509 https://reactome.org/PathwayBrowser/#/R-RNO-9612509 SGK phosphorylates SRF IEA Rattus norvegicus 456216 R-RNO-9612988 https://reactome.org/PathwayBrowser/#/R-RNO-9612988 Rap1-GTP phosphorylates Raf1 TAS Rattus norvegicus 456216 R-RNO-9613024 https://reactome.org/PathwayBrowser/#/R-RNO-9613024 Ntrk1,2,3 in Adcyap1:Adcyap1r1:Ntrk1,2,3 autophosphorylates TAS Rattus norvegicus 456216 R-RNO-9613030 https://reactome.org/PathwayBrowser/#/R-RNO-9613030 Ntrk1,2,3 in Ade-Rib:Adora2a:Ntrk1,2,3 autophosphorylates TAS Rattus norvegicus 456216 R-RNO-9618616 https://reactome.org/PathwayBrowser/#/R-RNO-9618616 CaMKII autophosphorylates TAS Rattus norvegicus 456216 R-RNO-9619165 https://reactome.org/PathwayBrowser/#/R-RNO-9619165 Camkk1 phosphorylates Camk4 TAS Rattus norvegicus 456216 R-RNO-9619355 https://reactome.org/PathwayBrowser/#/R-RNO-9619355 CaMKK autophosphorylates in the cytosol IEA Rattus norvegicus 456216 R-RNO-9619772 https://reactome.org/PathwayBrowser/#/R-RNO-9619772 Camk1 phosphorylates Arhgef7 TAS Rattus norvegicus 456216 R-RNO-9620003 https://reactome.org/PathwayBrowser/#/R-RNO-9620003 Rps6ka1 autophosphorylates TAS Rattus norvegicus 456216 R-RNO-9620437 https://reactome.org/PathwayBrowser/#/R-RNO-9620437 Camk2 phosphorylates GluA1 (Gria1) TAS Rattus norvegicus 456216 R-RNO-9624526 https://reactome.org/PathwayBrowser/#/R-RNO-9624526 AKT phosphorylates FOXO3 downstream of ESR1 and EGFR IEA Rattus norvegicus 456216 R-RNO-9624800 https://reactome.org/PathwayBrowser/#/R-RNO-9624800 CDK1 phosphorylates LBR IEA Rattus norvegicus 456216 R-RNO-9625487 https://reactome.org/PathwayBrowser/#/R-RNO-9625487 PTK2 autophosphorylates downstream of EGFR IEA Rattus norvegicus 456216 R-RNO-9626817 https://reactome.org/PathwayBrowser/#/R-RNO-9626817 PKC phosphorylates NCF1 IEA Rattus norvegicus 456216 R-RNO-9626832 https://reactome.org/PathwayBrowser/#/R-RNO-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Rattus norvegicus 456216 R-RNO-9626880 https://reactome.org/PathwayBrowser/#/R-RNO-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Rattus norvegicus 456216 R-RNO-9627089 https://reactome.org/PathwayBrowser/#/R-RNO-9627089 CASP9 is phosphorylated at T412 IEA Rattus norvegicus 456216 R-RNO-9632858 https://reactome.org/PathwayBrowser/#/R-RNO-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Rattus norvegicus 456216 R-RNO-9632868 https://reactome.org/PathwayBrowser/#/R-RNO-9632868 CDKN1B is phosphorylated in response to estrogen IEA Rattus norvegicus 456216 R-RNO-9634702 https://reactome.org/PathwayBrowser/#/R-RNO-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Rattus norvegicus 456216 R-RNO-9645442 https://reactome.org/PathwayBrowser/#/R-RNO-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Rattus norvegicus 456216 R-RNO-9645535 https://reactome.org/PathwayBrowser/#/R-RNO-9645535 ALPK1 phosphorylates TIFA IEA Rattus norvegicus 456216 R-RNO-964958 https://reactome.org/PathwayBrowser/#/R-RNO-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Rattus norvegicus 456216 R-RNO-964962 https://reactome.org/PathwayBrowser/#/R-RNO-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Rattus norvegicus 456216 R-RNO-964970 https://reactome.org/PathwayBrowser/#/R-RNO-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Rattus norvegicus 456216 R-RNO-9650858 https://reactome.org/PathwayBrowser/#/R-RNO-9650858 Meglitinides bind ABCC8 IEA Rattus norvegicus 456216 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 456216 R-RNO-9653503 https://reactome.org/PathwayBrowser/#/R-RNO-9653503 KRAS4B is phosphorylated on serine 181 IEA Rattus norvegicus 456216 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 456216 R-RNO-9661417 https://reactome.org/PathwayBrowser/#/R-RNO-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-9664221 https://reactome.org/PathwayBrowser/#/R-RNO-9664221 Atp2b1 (Pmca1) transports Ca2+ from the cytosol to the extracellular region TAS Rattus norvegicus 456216 R-RNO-9664232 https://reactome.org/PathwayBrowser/#/R-RNO-9664232 Atp2b2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region TAS Rattus norvegicus 456216 R-RNO-9668419 https://reactome.org/PathwayBrowser/#/R-RNO-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Rattus norvegicus 456216 R-RNO-9684118 https://reactome.org/PathwayBrowser/#/R-RNO-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus 456216 R-RNO-9686521 https://reactome.org/PathwayBrowser/#/R-RNO-9686521 CDK2:CCNA phosphorylates TERF2 IEA Rattus norvegicus 456216 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 456216 R-RNO-9699579 https://reactome.org/PathwayBrowser/#/R-RNO-9699579 AKT phosphorylates FOXO3 downstream of FLT3 IEA Rattus norvegicus 456216 R-RNO-9700168 https://reactome.org/PathwayBrowser/#/R-RNO-9700168 Active ALK phosphorylates IRS1 IEA Rattus norvegicus 456216 R-RNO-9700171 https://reactome.org/PathwayBrowser/#/R-RNO-9700171 Active ALK phosphorylates PLCG1 IEA Rattus norvegicus 456216 R-RNO-9700175 https://reactome.org/PathwayBrowser/#/R-RNO-9700175 Active ALK phosphorylates SHC1 IEA Rattus norvegicus 456216 R-RNO-9701488 https://reactome.org/PathwayBrowser/#/R-RNO-9701488 Active ALK phosphorylates JAK3 IEA Rattus norvegicus 456216 R-RNO-9706399 https://reactome.org/PathwayBrowser/#/R-RNO-9706399 RHOBTB3 hydrolyzes ATP IEA Rattus norvegicus 456216 R-RNO-9727198 https://reactome.org/PathwayBrowser/#/R-RNO-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 456216 R-RNO-9731111 https://reactome.org/PathwayBrowser/#/R-RNO-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Rattus norvegicus 456216 R-RNO-9732738 https://reactome.org/PathwayBrowser/#/R-RNO-9732738 JAK1-mediated phosphorylation of RAF1 IEA Rattus norvegicus 456216 R-RNO-9732753 https://reactome.org/PathwayBrowser/#/R-RNO-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Rattus norvegicus 456216 R-RNO-9734547 https://reactome.org/PathwayBrowser/#/R-RNO-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Rattus norvegicus 456216 R-RNO-9734687 https://reactome.org/PathwayBrowser/#/R-RNO-9734687 ORC6 is phosphorylated on T195 IEA Rattus norvegicus 456216 R-RNO-9748949 https://reactome.org/PathwayBrowser/#/R-RNO-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Rattus norvegicus 456216 R-RNO-9748963 https://reactome.org/PathwayBrowser/#/R-RNO-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Rattus norvegicus 456216 R-RNO-9748969 https://reactome.org/PathwayBrowser/#/R-RNO-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Rattus norvegicus 456216 R-RNO-9748999 https://reactome.org/PathwayBrowser/#/R-RNO-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Rattus norvegicus 456216 R-RNO-9750546 https://reactome.org/PathwayBrowser/#/R-RNO-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-9750617 https://reactome.org/PathwayBrowser/#/R-RNO-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-9750656 https://reactome.org/PathwayBrowser/#/R-RNO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Rattus norvegicus 456216 R-RNO-975103 https://reactome.org/PathwayBrowser/#/R-RNO-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Rattus norvegicus 456216 R-RNO-975139 https://reactome.org/PathwayBrowser/#/R-RNO-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Rattus norvegicus 456216 R-RNO-9753278 https://reactome.org/PathwayBrowser/#/R-RNO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 456216 R-RNO-9753283 https://reactome.org/PathwayBrowser/#/R-RNO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 456216 R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 456216 R-RNO-9754974 https://reactome.org/PathwayBrowser/#/R-RNO-9754974 ADK phosphorylates RBV IEA Rattus norvegicus 456216 R-RNO-9755013 https://reactome.org/PathwayBrowser/#/R-RNO-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Rattus norvegicus 456216 R-RNO-9759454 https://reactome.org/PathwayBrowser/#/R-RNO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Rattus norvegicus 456216 R-RNO-9759461 https://reactome.org/PathwayBrowser/#/R-RNO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Rattus norvegicus 456216 R-RNO-9760094 https://reactome.org/PathwayBrowser/#/R-RNO-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Rattus norvegicus 456216 R-RNO-9762094 https://reactome.org/PathwayBrowser/#/R-RNO-9762094 GSK3B phosphorylates p-NFE2L2 IEA Rattus norvegicus 456216 R-RNO-9770141 https://reactome.org/PathwayBrowser/#/R-RNO-9770141 Formation of the Spliceosomal C* complex IEA Rattus norvegicus 456216 R-RNO-9770142 https://reactome.org/PathwayBrowser/#/R-RNO-9770142 Formation of the Spliceosomal B complex IEA Rattus norvegicus 456216 R-RNO-9773803 https://reactome.org/PathwayBrowser/#/R-RNO-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Rattus norvegicus 456216 R-RNO-9794120 https://reactome.org/PathwayBrowser/#/R-RNO-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Rattus norvegicus 456216 R-RNO-9794572 https://reactome.org/PathwayBrowser/#/R-RNO-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Rattus norvegicus 456216 R-RNO-9796053 https://reactome.org/PathwayBrowser/#/R-RNO-9796053 PRKCI phosphorylates NFE2L2 IEA Rattus norvegicus 456216 R-RNO-9796067 https://reactome.org/PathwayBrowser/#/R-RNO-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Rattus norvegicus 456216 R-RNO-9815501 https://reactome.org/PathwayBrowser/#/R-RNO-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 IEA Rattus norvegicus 456216 R-RNO-9817397 https://reactome.org/PathwayBrowser/#/R-RNO-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Rattus norvegicus 456216 R-RNO-9818789 https://reactome.org/PathwayBrowser/#/R-RNO-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Rattus norvegicus 456216 R-RNO-9819106 https://reactome.org/PathwayBrowser/#/R-RNO-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Rattus norvegicus 456216 R-RNO-9823906 https://reactome.org/PathwayBrowser/#/R-RNO-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Rattus norvegicus 456216 R-RNO-9824882 https://reactome.org/PathwayBrowser/#/R-RNO-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Rattus norvegicus 456216 R-RNO-9824977 https://reactome.org/PathwayBrowser/#/R-RNO-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Rattus norvegicus 456216 R-RNO-9824994 https://reactome.org/PathwayBrowser/#/R-RNO-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Rattus norvegicus 456216 R-RNO-9824995 https://reactome.org/PathwayBrowser/#/R-RNO-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Rattus norvegicus 456216 R-RNO-9824999 https://reactome.org/PathwayBrowser/#/R-RNO-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Rattus norvegicus 456216 R-RNO-9825759 https://reactome.org/PathwayBrowser/#/R-RNO-9825759 MAPK-dependent phosphorylation of KARS IEA Rattus norvegicus 456216 R-RNO-982807 https://reactome.org/PathwayBrowser/#/R-RNO-982807 JAK2 phosphorylation of GHR IEA Rattus norvegicus 456216 R-RNO-982810 https://reactome.org/PathwayBrowser/#/R-RNO-982810 JAK2 phosphorylation IEA Rattus norvegicus 456216 R-RNO-983144 https://reactome.org/PathwayBrowser/#/R-RNO-983144 Transport of Antigen peptide in to ER IEA Rattus norvegicus 456216 R-RNO-983259 https://reactome.org/PathwayBrowser/#/R-RNO-983259 Kinesins move along microtubules consuming ATP IEA Rattus norvegicus 456216 R-RNO-9836159 https://reactome.org/PathwayBrowser/#/R-RNO-9836159 p-PKR dimer phosphorylates DHX9 IEA Rattus norvegicus 456216 R-RNO-9836184 https://reactome.org/PathwayBrowser/#/R-RNO-9836184 p-PKR dimer phosphorylates CDK1 IEA Rattus norvegicus 456216 R-RNO-9836322 https://reactome.org/PathwayBrowser/#/R-RNO-9836322 p-PKR dimer phosphorylates MKK6 IEA Rattus norvegicus 456216 R-RNO-9836362 https://reactome.org/PathwayBrowser/#/R-RNO-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Rattus norvegicus 456216 R-RNO-9836383 https://reactome.org/PathwayBrowser/#/R-RNO-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Rattus norvegicus 456216 R-RNO-9836404 https://reactome.org/PathwayBrowser/#/R-RNO-9836404 p-PKR dimer phosphorylates MAPT IEA Rattus norvegicus 456216 R-RNO-9836435 https://reactome.org/PathwayBrowser/#/R-RNO-9836435 p-PKR dimer phosphorylates SNCA IEA Rattus norvegicus 456216 R-RNO-9836515 https://reactome.org/PathwayBrowser/#/R-RNO-9836515 p-PKR dimer phosphorylates PTPN2 IEA Rattus norvegicus 456216 R-RNO-9836617 https://reactome.org/PathwayBrowser/#/R-RNO-9836617 p-PKR dimer phosphorylates SPHK1 IEA Rattus norvegicus 456216 R-RNO-9836664 https://reactome.org/PathwayBrowser/#/R-RNO-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Rattus norvegicus 456216 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus 456216 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus 456216 R-RNO-9837333 https://reactome.org/PathwayBrowser/#/R-RNO-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Rattus norvegicus 456216 R-RNO-9837337 https://reactome.org/PathwayBrowser/#/R-RNO-9837337 DCAKD phosphorylates DP-CoA IEA Rattus norvegicus 456216 R-RNO-9838004 https://reactome.org/PathwayBrowser/#/R-RNO-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Rattus norvegicus 456216 R-RNO-9838081 https://reactome.org/PathwayBrowser/#/R-RNO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Rattus norvegicus 456216 R-RNO-9838289 https://reactome.org/PathwayBrowser/#/R-RNO-9838289 CLPXP degrades mitochondrial matrix proteins IEA Rattus norvegicus 456216 R-RNO-9838321 https://reactome.org/PathwayBrowser/#/R-RNO-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Rattus norvegicus 456216 R-RNO-9839059 https://reactome.org/PathwayBrowser/#/R-RNO-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Rattus norvegicus 456216 R-RNO-9839105 https://reactome.org/PathwayBrowser/#/R-RNO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Rattus norvegicus 456216 R-RNO-9839113 https://reactome.org/PathwayBrowser/#/R-RNO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Rattus norvegicus 456216 R-RNO-9842648 https://reactome.org/PathwayBrowser/#/R-RNO-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 IEA Rattus norvegicus 456216 R-RNO-9842651 https://reactome.org/PathwayBrowser/#/R-RNO-9842651 Active LTK receptor phosphorylates SHC1 IEA Rattus norvegicus 456216 R-RNO-9842666 https://reactome.org/PathwayBrowser/#/R-RNO-9842666 Active LTK phosphorylates IRS1 IEA Rattus norvegicus 456216 R-RNO-9843721 https://reactome.org/PathwayBrowser/#/R-RNO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Rattus norvegicus 456216 R-RNO-9851972 https://reactome.org/PathwayBrowser/#/R-RNO-9851972 PLK1 phosphorylates FIRRM at S43 IEA Rattus norvegicus 456216 R-RNO-9853369 https://reactome.org/PathwayBrowser/#/R-RNO-9853369 PLK1 phosphorylates FIRMM at S744 IEA Rattus norvegicus 456216 R-RNO-9861642 https://reactome.org/PathwayBrowser/#/R-RNO-9861642 NEK1 phosphorylates ME1 IEA Rattus norvegicus 456216 R-RNO-994137 https://reactome.org/PathwayBrowser/#/R-RNO-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Rattus norvegicus 456216 R-RNO-994140 https://reactome.org/PathwayBrowser/#/R-RNO-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Rattus norvegicus 456216 R-SCE-1008248 https://reactome.org/PathwayBrowser/#/R-SCE-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Saccharomyces cerevisiae 456216 R-SCE-109624 https://reactome.org/PathwayBrowser/#/R-SCE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Saccharomyces cerevisiae 456216 R-SCE-109702 https://reactome.org/PathwayBrowser/#/R-SCE-109702 PDPK1 phosphorylates AKT2 IEA Saccharomyces cerevisiae 456216 R-SCE-109860 https://reactome.org/PathwayBrowser/#/R-SCE-109860 MAP2K1 phosphorylates MAPK3 IEA Saccharomyces cerevisiae 456216 R-SCE-109862 https://reactome.org/PathwayBrowser/#/R-SCE-109862 MAP2K2 phosphorylates MAPK1 IEA Saccharomyces cerevisiae 456216 R-SCE-110133 https://reactome.org/PathwayBrowser/#/R-SCE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Saccharomyces cerevisiae 456216 R-SCE-110144 https://reactome.org/PathwayBrowser/#/R-SCE-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Saccharomyces cerevisiae 456216 R-SCE-110145 https://reactome.org/PathwayBrowser/#/R-SCE-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Saccharomyces cerevisiae 456216 R-SCE-111898 https://reactome.org/PathwayBrowser/#/R-SCE-111898 Phosphorylation of cPLA2 by ERK-2 IEA Saccharomyces cerevisiae 456216 R-SCE-114683 https://reactome.org/PathwayBrowser/#/R-SCE-114683 Phosphorylation of Platelet Sec-1 IEA Saccharomyces cerevisiae 456216 R-SCE-114684 https://reactome.org/PathwayBrowser/#/R-SCE-114684 Phosphorylation of Syntaxin-4 IEA Saccharomyces cerevisiae 456216 R-SCE-1247935 https://reactome.org/PathwayBrowser/#/R-SCE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Saccharomyces cerevisiae 456216 R-SCE-1252253 https://reactome.org/PathwayBrowser/#/R-SCE-1252253 TIM23 PAM complex translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix TAS Saccharomyces cerevisiae 456216 R-SCE-1454916 https://reactome.org/PathwayBrowser/#/R-SCE-1454916 The ABCC family mediates organic anion transport IEA Saccharomyces cerevisiae 456216 R-SCE-1454928 https://reactome.org/PathwayBrowser/#/R-SCE-1454928 ABCG4 may mediate cholesterol efflux IEA Saccharomyces cerevisiae 456216 R-SCE-1483004 https://reactome.org/PathwayBrowser/#/R-SCE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Saccharomyces cerevisiae 456216 R-SCE-1483222 https://reactome.org/PathwayBrowser/#/R-SCE-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Saccharomyces cerevisiae 456216 R-SCE-156678 https://reactome.org/PathwayBrowser/#/R-SCE-156678 Activation of Cdc25C IEA Saccharomyces cerevisiae 456216 R-SCE-156699 https://reactome.org/PathwayBrowser/#/R-SCE-156699 Inactivation of Wee1 kinase IEA Saccharomyces cerevisiae 456216 R-SCE-162657 https://reactome.org/PathwayBrowser/#/R-SCE-162657 Inactivation of Myt1 kinase IEA Saccharomyces cerevisiae 456216 R-SCE-163215 https://reactome.org/PathwayBrowser/#/R-SCE-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Saccharomyces cerevisiae 456216 R-SCE-164832 https://reactome.org/PathwayBrowser/#/R-SCE-164832 ATPase synthesizes ATP IEA Saccharomyces cerevisiae 456216 R-SCE-164840 https://reactome.org/PathwayBrowser/#/R-SCE-164840 ADP and Pi bind to ATPase IEA Saccharomyces cerevisiae 456216 R-SCE-165726 https://reactome.org/PathwayBrowser/#/R-SCE-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Saccharomyces cerevisiae 456216 R-SCE-165766 https://reactome.org/PathwayBrowser/#/R-SCE-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Saccharomyces cerevisiae 456216 R-SCE-165777 https://reactome.org/PathwayBrowser/#/R-SCE-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Saccharomyces cerevisiae 456216 R-SCE-1675773 https://reactome.org/PathwayBrowser/#/R-SCE-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1675776 https://reactome.org/PathwayBrowser/#/R-SCE-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1675780 https://reactome.org/PathwayBrowser/#/R-SCE-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1675810 https://reactome.org/PathwayBrowser/#/R-SCE-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1675813 https://reactome.org/PathwayBrowser/#/R-SCE-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1675883 https://reactome.org/PathwayBrowser/#/R-SCE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1675939 https://reactome.org/PathwayBrowser/#/R-SCE-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1675961 https://reactome.org/PathwayBrowser/#/R-SCE-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1675974 https://reactome.org/PathwayBrowser/#/R-SCE-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1676024 https://reactome.org/PathwayBrowser/#/R-SCE-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1676082 https://reactome.org/PathwayBrowser/#/R-SCE-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1676134 https://reactome.org/PathwayBrowser/#/R-SCE-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1676145 https://reactome.org/PathwayBrowser/#/R-SCE-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Saccharomyces cerevisiae 456216 R-SCE-1676185 https://reactome.org/PathwayBrowser/#/R-SCE-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Saccharomyces cerevisiae 456216 R-SCE-168053 https://reactome.org/PathwayBrowser/#/R-SCE-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Saccharomyces cerevisiae 456216 R-SCE-168136 https://reactome.org/PathwayBrowser/#/R-SCE-168136 Activated JNKs phosphorylate c-JUN IEA Saccharomyces cerevisiae 456216 R-SCE-174389 https://reactome.org/PathwayBrowser/#/R-SCE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Saccharomyces cerevisiae 456216 R-SCE-174394 https://reactome.org/PathwayBrowser/#/R-SCE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Saccharomyces cerevisiae 456216 R-SCE-1855157 https://reactome.org/PathwayBrowser/#/R-SCE-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 456216 R-SCE-1855158 https://reactome.org/PathwayBrowser/#/R-SCE-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 456216 R-SCE-1855181 https://reactome.org/PathwayBrowser/#/R-SCE-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 456216 R-SCE-1855182 https://reactome.org/PathwayBrowser/#/R-SCE-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Saccharomyces cerevisiae 456216 R-SCE-1855193 https://reactome.org/PathwayBrowser/#/R-SCE-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 456216 R-SCE-1855194 https://reactome.org/PathwayBrowser/#/R-SCE-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 456216 R-SCE-1855207 https://reactome.org/PathwayBrowser/#/R-SCE-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 456216 R-SCE-1855216 https://reactome.org/PathwayBrowser/#/R-SCE-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Saccharomyces cerevisiae 456216 R-SCE-1855223 https://reactome.org/PathwayBrowser/#/R-SCE-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 456216 R-SCE-1855224 https://reactome.org/PathwayBrowser/#/R-SCE-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 456216 R-SCE-1855227 https://reactome.org/PathwayBrowser/#/R-SCE-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 456216 R-SCE-1855230 https://reactome.org/PathwayBrowser/#/R-SCE-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 456216 R-SCE-191380 https://reactome.org/PathwayBrowser/#/R-SCE-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Saccharomyces cerevisiae 456216 R-SCE-191414 https://reactome.org/PathwayBrowser/#/R-SCE-191414 MVD decarboxylates MVA5PP to IPPP IEA Saccharomyces cerevisiae 456216 R-SCE-194153 https://reactome.org/PathwayBrowser/#/R-SCE-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Saccharomyces cerevisiae 456216 R-SCE-196773 https://reactome.org/PathwayBrowser/#/R-SCE-196773 COASY phosphorylates DP-CoA IEA Saccharomyces cerevisiae 456216 R-SCE-196964 https://reactome.org/PathwayBrowser/#/R-SCE-196964 RFK:Mg2+ phosphorylates RIB IEA Saccharomyces cerevisiae 456216 R-SCE-197198 https://reactome.org/PathwayBrowser/#/R-SCE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Saccharomyces cerevisiae 456216 R-SCE-197958 https://reactome.org/PathwayBrowser/#/R-SCE-197958 FPGS-2 transforms THF to THFPG IEA Saccharomyces cerevisiae 456216 R-SCE-198314 https://reactome.org/PathwayBrowser/#/R-SCE-198314 DAG stimulates protein kinase C-delta IEA Saccharomyces cerevisiae 456216 R-SCE-198640 https://reactome.org/PathwayBrowser/#/R-SCE-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Saccharomyces cerevisiae 456216 R-SCE-198669 https://reactome.org/PathwayBrowser/#/R-SCE-198669 p38MAPK phosphorylates MSK1 IEA Saccharomyces cerevisiae 456216 R-SCE-198746 https://reactome.org/PathwayBrowser/#/R-SCE-198746 ERK1/2/5 activate RSK1/2/3 IEA Saccharomyces cerevisiae 456216 R-SCE-198756 https://reactome.org/PathwayBrowser/#/R-SCE-198756 ERK1/2 phosphorylates MSK1 IEA Saccharomyces cerevisiae 456216 R-SCE-199839 https://reactome.org/PathwayBrowser/#/R-SCE-199839 AKT can phosphorylate RSK IEA Saccharomyces cerevisiae 456216 R-SCE-200423 https://reactome.org/PathwayBrowser/#/R-SCE-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Saccharomyces cerevisiae 456216 R-SCE-200555 https://reactome.org/PathwayBrowser/#/R-SCE-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Saccharomyces cerevisiae 456216 R-SCE-200681 https://reactome.org/PathwayBrowser/#/R-SCE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Saccharomyces cerevisiae 456216 R-SCE-200682 https://reactome.org/PathwayBrowser/#/R-SCE-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Saccharomyces cerevisiae 456216 R-SCE-200711 https://reactome.org/PathwayBrowser/#/R-SCE-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Saccharomyces cerevisiae 456216 R-SCE-202111 https://reactome.org/PathwayBrowser/#/R-SCE-202111 AKT1 phosphorylates eNOS IEA Saccharomyces cerevisiae 456216 R-SCE-202222 https://reactome.org/PathwayBrowser/#/R-SCE-202222 Phosphorylation of PKC theta IEA Saccharomyces cerevisiae 456216 R-SCE-2029454 https://reactome.org/PathwayBrowser/#/R-SCE-2029454 Autophosphorylation of PAK1 IEA Saccharomyces cerevisiae 456216 R-SCE-2029473 https://reactome.org/PathwayBrowser/#/R-SCE-2029473 Branching and elongation of mother and daughter filaments IEA Saccharomyces cerevisiae 456216 R-SCE-2046087 https://reactome.org/PathwayBrowser/#/R-SCE-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Saccharomyces cerevisiae 456216 R-SCE-2046093 https://reactome.org/PathwayBrowser/#/R-SCE-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Saccharomyces cerevisiae 456216 R-SCE-2168079 https://reactome.org/PathwayBrowser/#/R-SCE-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Saccharomyces cerevisiae 456216 R-SCE-2214351 https://reactome.org/PathwayBrowser/#/R-SCE-2214351 PLK1 phosphorylates GORASP1 IEA Saccharomyces cerevisiae 456216 R-SCE-2430535 https://reactome.org/PathwayBrowser/#/R-SCE-2430535 MASTL phosphorylates ENSA IEA Saccharomyces cerevisiae 456216 R-SCE-2466068 https://reactome.org/PathwayBrowser/#/R-SCE-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Saccharomyces cerevisiae 456216 R-SCE-2529020 https://reactome.org/PathwayBrowser/#/R-SCE-2529020 CK2 phosphorylates condensin I subunits IEA Saccharomyces cerevisiae 456216 R-SCE-265783 https://reactome.org/PathwayBrowser/#/R-SCE-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Saccharomyces cerevisiae 456216 R-SCE-266082 https://reactome.org/PathwayBrowser/#/R-SCE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Saccharomyces cerevisiae 456216 R-SCE-2730835 https://reactome.org/PathwayBrowser/#/R-SCE-2730835 Autophosphorylation of PKC-theta IEA Saccharomyces cerevisiae 456216 R-SCE-3095901 https://reactome.org/PathwayBrowser/#/R-SCE-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Saccharomyces cerevisiae 456216 R-SCE-3371422 https://reactome.org/PathwayBrowser/#/R-SCE-3371422 ATP hydrolysis by HSP70 IEA Saccharomyces cerevisiae 456216 R-SCE-3371435 https://reactome.org/PathwayBrowser/#/R-SCE-3371435 Constitutive phosphorylation by GSK3 IEA Saccharomyces cerevisiae 456216 R-SCE-3371503 https://reactome.org/PathwayBrowser/#/R-SCE-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Saccharomyces cerevisiae 456216 R-SCE-3371531 https://reactome.org/PathwayBrowser/#/R-SCE-3371531 Constitutive phosphorylation by pERK1/2 IEA Saccharomyces cerevisiae 456216 R-SCE-381091 https://reactome.org/PathwayBrowser/#/R-SCE-381091 IRE1 dimer autophosphorylates IEA Saccharomyces cerevisiae 456216 R-SCE-382560 https://reactome.org/PathwayBrowser/#/R-SCE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Saccharomyces cerevisiae 456216 R-SCE-382575 https://reactome.org/PathwayBrowser/#/R-SCE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Saccharomyces cerevisiae 456216 R-SCE-389756 https://reactome.org/PathwayBrowser/#/R-SCE-389756 AKT interacts and phosphorylates Cot IEA Saccharomyces cerevisiae 456216 R-SCE-391266 https://reactome.org/PathwayBrowser/#/R-SCE-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Saccharomyces cerevisiae 456216 R-SCE-392530 https://reactome.org/PathwayBrowser/#/R-SCE-392530 p-S400-Cot phosphorylates NIK IEA Saccharomyces cerevisiae 456216 R-SCE-428273 https://reactome.org/PathwayBrowser/#/R-SCE-428273 SPHK1 phosphorylates sphingoid IEA Saccharomyces cerevisiae 456216 R-SCE-428941 https://reactome.org/PathwayBrowser/#/R-SCE-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Saccharomyces cerevisiae 456216 R-SCE-428961 https://reactome.org/PathwayBrowser/#/R-SCE-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Saccharomyces cerevisiae 456216 R-SCE-445079 https://reactome.org/PathwayBrowser/#/R-SCE-445079 Phosphorylation of L1 by ERK IEA Saccharomyces cerevisiae 456216 R-SCE-448955 https://reactome.org/PathwayBrowser/#/R-SCE-448955 Phosphorylation of MEF2 proteins by p38 IEA Saccharomyces cerevisiae 456216 R-SCE-450490 https://reactome.org/PathwayBrowser/#/R-SCE-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Saccharomyces cerevisiae 456216 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 456216 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 456216 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 456216 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 456216 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 456216 R-SCE-504054 https://reactome.org/PathwayBrowser/#/R-SCE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Saccharomyces cerevisiae 456216 R-SCE-508040 https://reactome.org/PathwayBrowser/#/R-SCE-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Saccharomyces cerevisiae 456216 R-SCE-5082405 https://reactome.org/PathwayBrowser/#/R-SCE-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Saccharomyces cerevisiae 456216 R-SCE-5218805 https://reactome.org/PathwayBrowser/#/R-SCE-5218805 PKC autophosphorylates IEA Saccharomyces cerevisiae 456216 R-SCE-5218821 https://reactome.org/PathwayBrowser/#/R-SCE-5218821 PDK1 phosphorylates PKC IEA Saccharomyces cerevisiae 456216 R-SCE-5218823 https://reactome.org/PathwayBrowser/#/R-SCE-5218823 PKC phosphorylates sphingosine kinase 1 IEA Saccharomyces cerevisiae 456216 R-SCE-5251955 https://reactome.org/PathwayBrowser/#/R-SCE-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Saccharomyces cerevisiae 456216 R-SCE-5251959 https://reactome.org/PathwayBrowser/#/R-SCE-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Saccharomyces cerevisiae 456216 R-SCE-5251989 https://reactome.org/PathwayBrowser/#/R-SCE-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Saccharomyces cerevisiae 456216 R-SCE-5252079 https://reactome.org/PathwayBrowser/#/R-SCE-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Saccharomyces cerevisiae 456216 R-SCE-535524 https://reactome.org/PathwayBrowser/#/R-SCE-535524 Phosphorylated Ire1 Dimer Binds ADP TAS Saccharomyces cerevisiae 456216 R-SCE-5358513 https://reactome.org/PathwayBrowser/#/R-SCE-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Saccharomyces cerevisiae 456216 R-SCE-5358525 https://reactome.org/PathwayBrowser/#/R-SCE-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Saccharomyces cerevisiae 456216 R-SCE-5358912 https://reactome.org/PathwayBrowser/#/R-SCE-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Saccharomyces cerevisiae 456216 R-SCE-5444511 https://reactome.org/PathwayBrowser/#/R-SCE-5444511 Formation of MSH2:MSH3 Complex IEA Saccharomyces cerevisiae 456216 R-SCE-5444516 https://reactome.org/PathwayBrowser/#/R-SCE-5444516 Formation of MSH2:MSH6 Complex IEA Saccharomyces cerevisiae 456216 R-SCE-5618107 https://reactome.org/PathwayBrowser/#/R-SCE-5618107 ATP binding to HSP90 triggers conformation change IEA Saccharomyces cerevisiae 456216 R-SCE-5623667 https://reactome.org/PathwayBrowser/#/R-SCE-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Saccharomyces cerevisiae 456216 R-SCE-5625784 https://reactome.org/PathwayBrowser/#/R-SCE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 456216 R-SCE-5627775 https://reactome.org/PathwayBrowser/#/R-SCE-5627775 Autophosphorylation of PAK1,2,3 IEA Saccharomyces cerevisiae 456216 R-SCE-5654989 https://reactome.org/PathwayBrowser/#/R-SCE-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Saccharomyces cerevisiae 456216 R-SCE-5662466 https://reactome.org/PathwayBrowser/#/R-SCE-5662466 XYLB phosphorylates D-xylulose IEA Saccharomyces cerevisiae 456216 R-SCE-5665868 https://reactome.org/PathwayBrowser/#/R-SCE-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Saccharomyces cerevisiae 456216 R-SCE-5668545 https://reactome.org/PathwayBrowser/#/R-SCE-5668545 NIK autophosphorylates on T559 IEA Saccharomyces cerevisiae 456216 R-SCE-5668932 https://reactome.org/PathwayBrowser/#/R-SCE-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Saccharomyces cerevisiae 456216 R-SCE-5671749 https://reactome.org/PathwayBrowser/#/R-SCE-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Saccharomyces cerevisiae 456216 R-SCE-5672008 https://reactome.org/PathwayBrowser/#/R-SCE-5672008 Thr-180 of ULK1 is phosphorylated IEA Saccharomyces cerevisiae 456216 R-SCE-5672012 https://reactome.org/PathwayBrowser/#/R-SCE-5672012 Beclin-1 complex phosphorylates PtdIns IEA Saccharomyces cerevisiae 456216 R-SCE-5674373 https://reactome.org/PathwayBrowser/#/R-SCE-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Saccharomyces cerevisiae 456216 R-SCE-5674496 https://reactome.org/PathwayBrowser/#/R-SCE-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Saccharomyces cerevisiae 456216 R-SCE-5675868 https://reactome.org/PathwayBrowser/#/R-SCE-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Saccharomyces cerevisiae 456216 R-SCE-5679041 https://reactome.org/PathwayBrowser/#/R-SCE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 456216 R-SCE-5679205 https://reactome.org/PathwayBrowser/#/R-SCE-5679205 ULK1 phosphorylates Beclin-1 IEA Saccharomyces cerevisiae 456216 R-SCE-5682026 https://reactome.org/PathwayBrowser/#/R-SCE-5682026 MRN bound to shortened telomeres activates ATM IEA Saccharomyces cerevisiae 456216 R-SCE-5682598 https://reactome.org/PathwayBrowser/#/R-SCE-5682598 ATM phosphorylates HERC2 IEA Saccharomyces cerevisiae 456216 R-SCE-5682983 https://reactome.org/PathwayBrowser/#/R-SCE-5682983 ATM phosphorylates WHSC1 IEA Saccharomyces cerevisiae 456216 R-SCE-5683425 https://reactome.org/PathwayBrowser/#/R-SCE-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Saccharomyces cerevisiae 456216 R-SCE-5683792 https://reactome.org/PathwayBrowser/#/R-SCE-5683792 p-T68-CHEK2 autophosphorylates IEA Saccharomyces cerevisiae 456216 R-SCE-5685230 https://reactome.org/PathwayBrowser/#/R-SCE-5685230 CHEK1 phosphorylates RAD51 IEA Saccharomyces cerevisiae 456216 R-SCE-5687086 https://reactome.org/PathwayBrowser/#/R-SCE-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Saccharomyces cerevisiae 456216 R-SCE-5692462 https://reactome.org/PathwayBrowser/#/R-SCE-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Saccharomyces cerevisiae 456216 R-SCE-5692480 https://reactome.org/PathwayBrowser/#/R-SCE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Saccharomyces cerevisiae 456216 R-SCE-5693536 https://reactome.org/PathwayBrowser/#/R-SCE-5693536 ATM phosphorylates MDC1 IEA Saccharomyces cerevisiae 456216 R-SCE-5693540 https://reactome.org/PathwayBrowser/#/R-SCE-5693540 MRN activates ATM IEA Saccharomyces cerevisiae 456216 R-SCE-5693549 https://reactome.org/PathwayBrowser/#/R-SCE-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Saccharomyces cerevisiae 456216 R-SCE-5693598 https://reactome.org/PathwayBrowser/#/R-SCE-5693598 ATM phosphorylates NBN IEA Saccharomyces cerevisiae 456216 R-SCE-5694441 https://reactome.org/PathwayBrowser/#/R-SCE-5694441 CSNK1D phosphorylates SEC23 IEA Saccharomyces cerevisiae 456216 R-SCE-5696074 https://reactome.org/PathwayBrowser/#/R-SCE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Saccharomyces cerevisiae 456216 R-SCE-5696839 https://reactome.org/PathwayBrowser/#/R-SCE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Saccharomyces cerevisiae 456216 R-SCE-6782131 https://reactome.org/PathwayBrowser/#/R-SCE-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Saccharomyces cerevisiae 456216 R-SCE-6788798 https://reactome.org/PathwayBrowser/#/R-SCE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 456216 R-SCE-6788810 https://reactome.org/PathwayBrowser/#/R-SCE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 456216 R-SCE-6795290 https://reactome.org/PathwayBrowser/#/R-SCE-6795290 TORC2 complex phosphorylates SGK1 IEA Saccharomyces cerevisiae 456216 R-SCE-6795473 https://reactome.org/PathwayBrowser/#/R-SCE-6795473 PDPK1 phosphorylates SGK1 IEA Saccharomyces cerevisiae 456216 R-SCE-6797606 https://reactome.org/PathwayBrowser/#/R-SCE-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Saccharomyces cerevisiae 456216 R-SCE-6798174 https://reactome.org/PathwayBrowser/#/R-SCE-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Saccharomyces cerevisiae 456216 R-SCE-6801342 https://reactome.org/PathwayBrowser/#/R-SCE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Saccharomyces cerevisiae 456216 R-SCE-6801456 https://reactome.org/PathwayBrowser/#/R-SCE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Saccharomyces cerevisiae 456216 R-SCE-6802973 https://reactome.org/PathwayBrowser/#/R-SCE-6802973 PLK3 phosphorylates CDC25C IEA Saccharomyces cerevisiae 456216 R-SCE-6806877 https://reactome.org/PathwayBrowser/#/R-SCE-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Saccharomyces cerevisiae 456216 R-SCE-6806967 https://reactome.org/PathwayBrowser/#/R-SCE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Saccharomyces cerevisiae 456216 R-SCE-6807868 https://reactome.org/PathwayBrowser/#/R-SCE-6807868 GBF1 stimulates ARF nucleotide exchange IEA Saccharomyces cerevisiae 456216 R-SCE-6810233 https://reactome.org/PathwayBrowser/#/R-SCE-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Saccharomyces cerevisiae 456216 R-SCE-6811522 https://reactome.org/PathwayBrowser/#/R-SCE-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Saccharomyces cerevisiae 456216 R-SCE-6814119 https://reactome.org/PathwayBrowser/#/R-SCE-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Saccharomyces cerevisiae 456216 R-SCE-6814120 https://reactome.org/PathwayBrowser/#/R-SCE-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Saccharomyces cerevisiae 456216 R-SCE-6814124 https://reactome.org/PathwayBrowser/#/R-SCE-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Saccharomyces cerevisiae 456216 R-SCE-68954 https://reactome.org/PathwayBrowser/#/R-SCE-68954 Mcm2-7 is phosphorylated by DDK IEA Saccharomyces cerevisiae 456216 R-SCE-69063 https://reactome.org/PathwayBrowser/#/R-SCE-69063 Loading of PCNA - Sliding Clamp Formation IEA Saccharomyces cerevisiae 456216 R-SCE-69604 https://reactome.org/PathwayBrowser/#/R-SCE-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Saccharomyces cerevisiae 456216 R-SCE-69608 https://reactome.org/PathwayBrowser/#/R-SCE-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Saccharomyces cerevisiae 456216 R-SCE-70349 https://reactome.org/PathwayBrowser/#/R-SCE-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Saccharomyces cerevisiae 456216 R-SCE-70420 https://reactome.org/PathwayBrowser/#/R-SCE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Saccharomyces cerevisiae 456216 R-SCE-70467 https://reactome.org/PathwayBrowser/#/R-SCE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 456216 R-SCE-70486 https://reactome.org/PathwayBrowser/#/R-SCE-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Saccharomyces cerevisiae 456216 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 456216 R-SCE-70555 https://reactome.org/PathwayBrowser/#/R-SCE-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Saccharomyces cerevisiae 456216 R-SCE-70606 https://reactome.org/PathwayBrowser/#/R-SCE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Saccharomyces cerevisiae 456216 R-SCE-70967 https://reactome.org/PathwayBrowser/#/R-SCE-70967 IDH3 complex decarboxylates isocitrate IEA Saccharomyces cerevisiae 456216 R-SCE-70997 https://reactome.org/PathwayBrowser/#/R-SCE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Saccharomyces cerevisiae 456216 R-SCE-71401 https://reactome.org/PathwayBrowser/#/R-SCE-71401 OGDH dimer decarboxylates 2-OG IEA Saccharomyces cerevisiae 456216 R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 456216 R-SCE-71802 https://reactome.org/PathwayBrowser/#/R-SCE-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 456216 R-SCE-71850 https://reactome.org/PathwayBrowser/#/R-SCE-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Saccharomyces cerevisiae 456216 R-SCE-72621 https://reactome.org/PathwayBrowser/#/R-SCE-72621 Ribosomal scanning IEA Saccharomyces cerevisiae 456216 R-SCE-72647 https://reactome.org/PathwayBrowser/#/R-SCE-72647 Cap-bound mRNA is activated by helicases IEA Saccharomyces cerevisiae 456216 R-SCE-73548 https://reactome.org/PathwayBrowser/#/R-SCE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Saccharomyces cerevisiae 456216 R-SCE-73577 https://reactome.org/PathwayBrowser/#/R-SCE-73577 CAD hexamer transforms L-Gln to CAP IEA Saccharomyces cerevisiae 456216 R-SCE-73635 https://reactome.org/PathwayBrowser/#/R-SCE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Saccharomyces cerevisiae 456216 R-SCE-73647 https://reactome.org/PathwayBrowser/#/R-SCE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Saccharomyces cerevisiae 456216 R-SCE-73788 https://reactome.org/PathwayBrowser/#/R-SCE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Saccharomyces cerevisiae 456216 R-SCE-73810 https://reactome.org/PathwayBrowser/#/R-SCE-73810 FGAM + ATP => AIR + ADP + Pi IEA Saccharomyces cerevisiae 456216 R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 456216 R-SCE-73814 https://reactome.org/PathwayBrowser/#/R-SCE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Saccharomyces cerevisiae 456216 R-SCE-75010 https://reactome.org/PathwayBrowser/#/R-SCE-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Saccharomyces cerevisiae 456216 R-SCE-75125 https://reactome.org/PathwayBrowser/#/R-SCE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Saccharomyces cerevisiae 456216 R-SCE-75126 https://reactome.org/PathwayBrowser/#/R-SCE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Saccharomyces cerevisiae 456216 R-SCE-75809 https://reactome.org/PathwayBrowser/#/R-SCE-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Saccharomyces cerevisiae 456216 R-SCE-75851 https://reactome.org/PathwayBrowser/#/R-SCE-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 456216 R-SCE-75887 https://reactome.org/PathwayBrowser/#/R-SCE-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Saccharomyces cerevisiae 456216 R-SCE-75949 https://reactome.org/PathwayBrowser/#/R-SCE-75949 RNA Polymerase II Promoter Opening: First Transition IEA Saccharomyces cerevisiae 456216 R-SCE-77071 https://reactome.org/PathwayBrowser/#/R-SCE-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Saccharomyces cerevisiae 456216 R-SCE-8847638 https://reactome.org/PathwayBrowser/#/R-SCE-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Saccharomyces cerevisiae 456216 R-SCE-8850945 https://reactome.org/PathwayBrowser/#/R-SCE-8850945 Casein kinase II phosphorylates PTEN IEA Saccharomyces cerevisiae 456216 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 456216 R-SCE-8856813 https://reactome.org/PathwayBrowser/#/R-SCE-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Saccharomyces cerevisiae 456216 R-SCE-8868066 https://reactome.org/PathwayBrowser/#/R-SCE-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Saccharomyces cerevisiae 456216 R-SCE-8876889 https://reactome.org/PathwayBrowser/#/R-SCE-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 456216 R-SCE-8948039 https://reactome.org/PathwayBrowser/#/R-SCE-8948039 FUNDC1 is phosphorylated by CK2 IEA Saccharomyces cerevisiae 456216 R-SCE-8948146 https://reactome.org/PathwayBrowser/#/R-SCE-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Saccharomyces cerevisiae 456216 R-SCE-8954327 https://reactome.org/PathwayBrowser/#/R-SCE-8954327 UCKL1 phosphorylates urindine, cytidine IEA Saccharomyces cerevisiae 456216 R-SCE-8955844 https://reactome.org/PathwayBrowser/#/R-SCE-8955844 RBKS phosphorylates ribose to R5P IEA Saccharomyces cerevisiae 456216 R-SCE-9008043 https://reactome.org/PathwayBrowser/#/R-SCE-9008043 MAPK8 phosphorylation IEA Saccharomyces cerevisiae 456216 R-SCE-9012319 https://reactome.org/PathwayBrowser/#/R-SCE-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Saccharomyces cerevisiae 456216 R-SCE-9033756 https://reactome.org/PathwayBrowser/#/R-SCE-9033756 PEX1:PEX6:PEX15:Ub:PEX5:PEX14:PEX13:PEX17:PEX1:PEX6:PEX15 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX17:PEX1:PEX6:PEX15 TAS Saccharomyces cerevisiae 456216 R-SCE-917693 https://reactome.org/PathwayBrowser/#/R-SCE-917693 ESCRT Disassembly IEA Saccharomyces cerevisiae 456216 R-SCE-917841 https://reactome.org/PathwayBrowser/#/R-SCE-917841 Acidification of Tf:TfR1 containing endosome IEA Saccharomyces cerevisiae 456216 R-SCE-917979 https://reactome.org/PathwayBrowser/#/R-SCE-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Saccharomyces cerevisiae 456216 R-SCE-927889 https://reactome.org/PathwayBrowser/#/R-SCE-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Saccharomyces cerevisiae 456216 R-SCE-936883 https://reactome.org/PathwayBrowser/#/R-SCE-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Saccharomyces cerevisiae 456216 R-SCE-936895 https://reactome.org/PathwayBrowser/#/R-SCE-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Saccharomyces cerevisiae 456216 R-SCE-939763 https://reactome.org/PathwayBrowser/#/R-SCE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Saccharomyces cerevisiae 456216 R-SCE-947591 https://reactome.org/PathwayBrowser/#/R-SCE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Saccharomyces cerevisiae 456216 R-SCE-9606884 https://reactome.org/PathwayBrowser/#/R-SCE-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Saccharomyces cerevisiae 456216 R-SCE-9612509 https://reactome.org/PathwayBrowser/#/R-SCE-9612509 SGK phosphorylates SRF IEA Saccharomyces cerevisiae 456216 R-SCE-9626817 https://reactome.org/PathwayBrowser/#/R-SCE-9626817 PKC phosphorylates NCF1 IEA Saccharomyces cerevisiae 456216 R-SCE-9628640 https://reactome.org/PathwayBrowser/#/R-SCE-9628640 SBH1:GET3:ADP:GET1:GET2 dissociates yielding SBH1 in the endoplasmic reticulum membrane TAS Saccharomyces cerevisiae 456216 R-SCE-9628646 https://reactome.org/PathwayBrowser/#/R-SCE-9628646 SBH1:GET3:ADP binds GET1:GET2 TAS Saccharomyces cerevisiae 456216 R-SCE-9629050 https://reactome.org/PathwayBrowser/#/R-SCE-9629050 SBH1:GET3:ATP:GET4:MDY2:SGT2 dissociates and GET3 hydrolyzes ATP yielding SBH1:GET3:ADP TAS Saccharomyces cerevisiae 456216 R-SCE-9632858 https://reactome.org/PathwayBrowser/#/R-SCE-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Saccharomyces cerevisiae 456216 R-SCE-9633480 https://reactome.org/PathwayBrowser/#/R-SCE-9633480 GCN2 phosphorylates SUI2 TAS Saccharomyces cerevisiae 456216 R-SCE-9633750 https://reactome.org/PathwayBrowser/#/R-SCE-9633750 GCN2 dimer autophosphorylates TAS Saccharomyces cerevisiae 456216 R-SCE-964958 https://reactome.org/PathwayBrowser/#/R-SCE-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Saccharomyces cerevisiae 456216 R-SCE-964962 https://reactome.org/PathwayBrowser/#/R-SCE-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Saccharomyces cerevisiae 456216 R-SCE-964970 https://reactome.org/PathwayBrowser/#/R-SCE-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Saccharomyces cerevisiae 456216 R-SCE-9661417 https://reactome.org/PathwayBrowser/#/R-SCE-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 456216 R-SCE-9684118 https://reactome.org/PathwayBrowser/#/R-SCE-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Saccharomyces cerevisiae 456216 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 456216 R-SCE-9748949 https://reactome.org/PathwayBrowser/#/R-SCE-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Saccharomyces cerevisiae 456216 R-SCE-9748963 https://reactome.org/PathwayBrowser/#/R-SCE-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Saccharomyces cerevisiae 456216 R-SCE-9748969 https://reactome.org/PathwayBrowser/#/R-SCE-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Saccharomyces cerevisiae 456216 R-SCE-9748999 https://reactome.org/PathwayBrowser/#/R-SCE-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Saccharomyces cerevisiae 456216 R-SCE-9749381 https://reactome.org/PathwayBrowser/#/R-SCE-9749381 ATP-dependent release of CDT1 from the OCCM complex in budding yeast TAS Saccharomyces cerevisiae 456216 R-SCE-9750656 https://reactome.org/PathwayBrowser/#/R-SCE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Saccharomyces cerevisiae 456216 R-SCE-9753278 https://reactome.org/PathwayBrowser/#/R-SCE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 456216 R-SCE-9753283 https://reactome.org/PathwayBrowser/#/R-SCE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 456216 R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 456216 R-SCE-9754974 https://reactome.org/PathwayBrowser/#/R-SCE-9754974 ADK phosphorylates RBV IEA Saccharomyces cerevisiae 456216 R-SCE-9755013 https://reactome.org/PathwayBrowser/#/R-SCE-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Saccharomyces cerevisiae 456216 R-SCE-9760094 https://reactome.org/PathwayBrowser/#/R-SCE-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Saccharomyces cerevisiae 456216 R-SCE-9794120 https://reactome.org/PathwayBrowser/#/R-SCE-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Saccharomyces cerevisiae 456216 R-SCE-9794572 https://reactome.org/PathwayBrowser/#/R-SCE-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Saccharomyces cerevisiae 456216 R-SCE-9824977 https://reactome.org/PathwayBrowser/#/R-SCE-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Saccharomyces cerevisiae 456216 R-SCE-9824994 https://reactome.org/PathwayBrowser/#/R-SCE-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Saccharomyces cerevisiae 456216 R-SCE-9824995 https://reactome.org/PathwayBrowser/#/R-SCE-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Saccharomyces cerevisiae 456216 R-SCE-9824999 https://reactome.org/PathwayBrowser/#/R-SCE-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Saccharomyces cerevisiae 456216 R-SCE-9837337 https://reactome.org/PathwayBrowser/#/R-SCE-9837337 DCAKD phosphorylates DP-CoA IEA Saccharomyces cerevisiae 456216 R-SCE-9838004 https://reactome.org/PathwayBrowser/#/R-SCE-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 456216 R-SCE-9838081 https://reactome.org/PathwayBrowser/#/R-SCE-9838081 LONP1 degrades mitochondrial matrix proteins IEA Saccharomyces cerevisiae 456216 R-SCE-9838321 https://reactome.org/PathwayBrowser/#/R-SCE-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Saccharomyces cerevisiae 456216 R-SCE-9839105 https://reactome.org/PathwayBrowser/#/R-SCE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Saccharomyces cerevisiae 456216 R-SCE-9839113 https://reactome.org/PathwayBrowser/#/R-SCE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 456216 R-SCE-9839836 https://reactome.org/PathwayBrowser/#/R-SCE-9839836 YME1 degrades TIM10 TAS Saccharomyces cerevisiae 456216 R-SCE-9843721 https://reactome.org/PathwayBrowser/#/R-SCE-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Saccharomyces cerevisiae 456216 R-SPO-109624 https://reactome.org/PathwayBrowser/#/R-SPO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Schizosaccharomyces pombe 456216 R-SPO-109702 https://reactome.org/PathwayBrowser/#/R-SPO-109702 PDPK1 phosphorylates AKT2 IEA Schizosaccharomyces pombe 456216 R-SPO-109860 https://reactome.org/PathwayBrowser/#/R-SPO-109860 MAP2K1 phosphorylates MAPK3 IEA Schizosaccharomyces pombe 456216 R-SPO-109862 https://reactome.org/PathwayBrowser/#/R-SPO-109862 MAP2K2 phosphorylates MAPK1 IEA Schizosaccharomyces pombe 456216 R-SPO-110133 https://reactome.org/PathwayBrowser/#/R-SPO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Schizosaccharomyces pombe 456216 R-SPO-110144 https://reactome.org/PathwayBrowser/#/R-SPO-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Schizosaccharomyces pombe 456216 R-SPO-110145 https://reactome.org/PathwayBrowser/#/R-SPO-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Schizosaccharomyces pombe 456216 R-SPO-111898 https://reactome.org/PathwayBrowser/#/R-SPO-111898 Phosphorylation of cPLA2 by ERK-2 IEA Schizosaccharomyces pombe 456216 R-SPO-114683 https://reactome.org/PathwayBrowser/#/R-SPO-114683 Phosphorylation of Platelet Sec-1 IEA Schizosaccharomyces pombe 456216 R-SPO-114684 https://reactome.org/PathwayBrowser/#/R-SPO-114684 Phosphorylation of Syntaxin-4 IEA Schizosaccharomyces pombe 456216 R-SPO-1247935 https://reactome.org/PathwayBrowser/#/R-SPO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Schizosaccharomyces pombe 456216 R-SPO-1358791 https://reactome.org/PathwayBrowser/#/R-SPO-1358791 Phosphorylation of USP8 by P-AKT IEA Schizosaccharomyces pombe 456216 R-SPO-1369065 https://reactome.org/PathwayBrowser/#/R-SPO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Schizosaccharomyces pombe 456216 R-SPO-1454916 https://reactome.org/PathwayBrowser/#/R-SPO-1454916 The ABCC family mediates organic anion transport IEA Schizosaccharomyces pombe 456216 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 456216 R-SPO-1483004 https://reactome.org/PathwayBrowser/#/R-SPO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Schizosaccharomyces pombe 456216 R-SPO-1483222 https://reactome.org/PathwayBrowser/#/R-SPO-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Schizosaccharomyces pombe 456216 R-SPO-156678 https://reactome.org/PathwayBrowser/#/R-SPO-156678 Activation of Cdc25C IEA Schizosaccharomyces pombe 456216 R-SPO-156682 https://reactome.org/PathwayBrowser/#/R-SPO-156682 PLK1 phosphorylates NUDC IEA Schizosaccharomyces pombe 456216 R-SPO-156699 https://reactome.org/PathwayBrowser/#/R-SPO-156699 Inactivation of Wee1 kinase IEA Schizosaccharomyces pombe 456216 R-SPO-162657 https://reactome.org/PathwayBrowser/#/R-SPO-162657 Inactivation of Myt1 kinase IEA Schizosaccharomyces pombe 456216 R-SPO-163215 https://reactome.org/PathwayBrowser/#/R-SPO-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1632857 https://reactome.org/PathwayBrowser/#/R-SPO-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Schizosaccharomyces pombe 456216 R-SPO-165162 https://reactome.org/PathwayBrowser/#/R-SPO-165162 Phosphorylation of TSC2 by PKB IEA Schizosaccharomyces pombe 456216 R-SPO-165182 https://reactome.org/PathwayBrowser/#/R-SPO-165182 Phosphorylation of complexed TSC2 by PKB IEA Schizosaccharomyces pombe 456216 R-SPO-165726 https://reactome.org/PathwayBrowser/#/R-SPO-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Schizosaccharomyces pombe 456216 R-SPO-165766 https://reactome.org/PathwayBrowser/#/R-SPO-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Schizosaccharomyces pombe 456216 R-SPO-165777 https://reactome.org/PathwayBrowser/#/R-SPO-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Schizosaccharomyces pombe 456216 R-SPO-1675773 https://reactome.org/PathwayBrowser/#/R-SPO-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1675776 https://reactome.org/PathwayBrowser/#/R-SPO-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1675780 https://reactome.org/PathwayBrowser/#/R-SPO-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1675810 https://reactome.org/PathwayBrowser/#/R-SPO-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1675813 https://reactome.org/PathwayBrowser/#/R-SPO-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1675883 https://reactome.org/PathwayBrowser/#/R-SPO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1675939 https://reactome.org/PathwayBrowser/#/R-SPO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1675961 https://reactome.org/PathwayBrowser/#/R-SPO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1675974 https://reactome.org/PathwayBrowser/#/R-SPO-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1676024 https://reactome.org/PathwayBrowser/#/R-SPO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1676082 https://reactome.org/PathwayBrowser/#/R-SPO-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1676134 https://reactome.org/PathwayBrowser/#/R-SPO-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1676145 https://reactome.org/PathwayBrowser/#/R-SPO-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Schizosaccharomyces pombe 456216 R-SPO-1676185 https://reactome.org/PathwayBrowser/#/R-SPO-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Schizosaccharomyces pombe 456216 R-SPO-168053 https://reactome.org/PathwayBrowser/#/R-SPO-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Schizosaccharomyces pombe 456216 R-SPO-174164 https://reactome.org/PathwayBrowser/#/R-SPO-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Schizosaccharomyces pombe 456216 R-SPO-174367 https://reactome.org/PathwayBrowser/#/R-SPO-174367 GCL ligates L-Glu to L-Cys IEA Schizosaccharomyces pombe 456216 R-SPO-174389 https://reactome.org/PathwayBrowser/#/R-SPO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Schizosaccharomyces pombe 456216 R-SPO-174394 https://reactome.org/PathwayBrowser/#/R-SPO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Schizosaccharomyces pombe 456216 R-SPO-1855157 https://reactome.org/PathwayBrowser/#/R-SPO-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 456216 R-SPO-1855158 https://reactome.org/PathwayBrowser/#/R-SPO-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 456216 R-SPO-1855181 https://reactome.org/PathwayBrowser/#/R-SPO-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 456216 R-SPO-1855182 https://reactome.org/PathwayBrowser/#/R-SPO-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Schizosaccharomyces pombe 456216 R-SPO-1855193 https://reactome.org/PathwayBrowser/#/R-SPO-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 456216 R-SPO-1855194 https://reactome.org/PathwayBrowser/#/R-SPO-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 456216 R-SPO-1855207 https://reactome.org/PathwayBrowser/#/R-SPO-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 456216 R-SPO-1855216 https://reactome.org/PathwayBrowser/#/R-SPO-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Schizosaccharomyces pombe 456216 R-SPO-1855223 https://reactome.org/PathwayBrowser/#/R-SPO-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 456216 R-SPO-1855224 https://reactome.org/PathwayBrowser/#/R-SPO-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 456216 R-SPO-1855227 https://reactome.org/PathwayBrowser/#/R-SPO-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 456216 R-SPO-1855230 https://reactome.org/PathwayBrowser/#/R-SPO-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 456216 R-SPO-187948 https://reactome.org/PathwayBrowser/#/R-SPO-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Schizosaccharomyces pombe 456216 R-SPO-187949 https://reactome.org/PathwayBrowser/#/R-SPO-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Schizosaccharomyces pombe 456216 R-SPO-191380 https://reactome.org/PathwayBrowser/#/R-SPO-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Schizosaccharomyces pombe 456216 R-SPO-191414 https://reactome.org/PathwayBrowser/#/R-SPO-191414 MVD decarboxylates MVA5PP to IPPP IEA Schizosaccharomyces pombe 456216 R-SPO-193362 https://reactome.org/PathwayBrowser/#/R-SPO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 456216 R-SPO-194153 https://reactome.org/PathwayBrowser/#/R-SPO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 456216 R-SPO-196773 https://reactome.org/PathwayBrowser/#/R-SPO-196773 COASY phosphorylates DP-CoA IEA Schizosaccharomyces pombe 456216 R-SPO-196964 https://reactome.org/PathwayBrowser/#/R-SPO-196964 RFK:Mg2+ phosphorylates RIB IEA Schizosaccharomyces pombe 456216 R-SPO-197198 https://reactome.org/PathwayBrowser/#/R-SPO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Schizosaccharomyces pombe 456216 R-SPO-197958 https://reactome.org/PathwayBrowser/#/R-SPO-197958 FPGS-2 transforms THF to THFPG IEA Schizosaccharomyces pombe 456216 R-SPO-198314 https://reactome.org/PathwayBrowser/#/R-SPO-198314 DAG stimulates protein kinase C-delta IEA Schizosaccharomyces pombe 456216 R-SPO-198609 https://reactome.org/PathwayBrowser/#/R-SPO-198609 AKT phosphorylates TSC2, inhibiting it IEA Schizosaccharomyces pombe 456216 R-SPO-198640 https://reactome.org/PathwayBrowser/#/R-SPO-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Schizosaccharomyces pombe 456216 R-SPO-198669 https://reactome.org/PathwayBrowser/#/R-SPO-198669 p38MAPK phosphorylates MSK1 IEA Schizosaccharomyces pombe 456216 R-SPO-198746 https://reactome.org/PathwayBrowser/#/R-SPO-198746 ERK1/2/5 activate RSK1/2/3 IEA Schizosaccharomyces pombe 456216 R-SPO-198756 https://reactome.org/PathwayBrowser/#/R-SPO-198756 ERK1/2 phosphorylates MSK1 IEA Schizosaccharomyces pombe 456216 R-SPO-199839 https://reactome.org/PathwayBrowser/#/R-SPO-199839 AKT can phosphorylate RSK IEA Schizosaccharomyces pombe 456216 R-SPO-200423 https://reactome.org/PathwayBrowser/#/R-SPO-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Schizosaccharomyces pombe 456216 R-SPO-200555 https://reactome.org/PathwayBrowser/#/R-SPO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Schizosaccharomyces pombe 456216 R-SPO-200681 https://reactome.org/PathwayBrowser/#/R-SPO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Schizosaccharomyces pombe 456216 R-SPO-200682 https://reactome.org/PathwayBrowser/#/R-SPO-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Schizosaccharomyces pombe 456216 R-SPO-200711 https://reactome.org/PathwayBrowser/#/R-SPO-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Schizosaccharomyces pombe 456216 R-SPO-202111 https://reactome.org/PathwayBrowser/#/R-SPO-202111 AKT1 phosphorylates eNOS IEA Schizosaccharomyces pombe 456216 R-SPO-202222 https://reactome.org/PathwayBrowser/#/R-SPO-202222 Phosphorylation of PKC theta IEA Schizosaccharomyces pombe 456216 R-SPO-2029454 https://reactome.org/PathwayBrowser/#/R-SPO-2029454 Autophosphorylation of PAK1 IEA Schizosaccharomyces pombe 456216 R-SPO-2029473 https://reactome.org/PathwayBrowser/#/R-SPO-2029473 Branching and elongation of mother and daughter filaments IEA Schizosaccharomyces pombe 456216 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 456216 R-SPO-2168079 https://reactome.org/PathwayBrowser/#/R-SPO-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Schizosaccharomyces pombe 456216 R-SPO-2214351 https://reactome.org/PathwayBrowser/#/R-SPO-2214351 PLK1 phosphorylates GORASP1 IEA Schizosaccharomyces pombe 456216 R-SPO-2430535 https://reactome.org/PathwayBrowser/#/R-SPO-2430535 MASTL phosphorylates ENSA IEA Schizosaccharomyces pombe 456216 R-SPO-2466068 https://reactome.org/PathwayBrowser/#/R-SPO-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Schizosaccharomyces pombe 456216 R-SPO-2529020 https://reactome.org/PathwayBrowser/#/R-SPO-2529020 CK2 phosphorylates condensin I subunits IEA Schizosaccharomyces pombe 456216 R-SPO-2730835 https://reactome.org/PathwayBrowser/#/R-SPO-2730835 Autophosphorylation of PKC-theta IEA Schizosaccharomyces pombe 456216 R-SPO-3095901 https://reactome.org/PathwayBrowser/#/R-SPO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Schizosaccharomyces pombe 456216 R-SPO-3371422 https://reactome.org/PathwayBrowser/#/R-SPO-3371422 ATP hydrolysis by HSP70 IEA Schizosaccharomyces pombe 456216 R-SPO-3371435 https://reactome.org/PathwayBrowser/#/R-SPO-3371435 Constitutive phosphorylation by GSK3 IEA Schizosaccharomyces pombe 456216 R-SPO-3371503 https://reactome.org/PathwayBrowser/#/R-SPO-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Schizosaccharomyces pombe 456216 R-SPO-3371531 https://reactome.org/PathwayBrowser/#/R-SPO-3371531 Constitutive phosphorylation by pERK1/2 IEA Schizosaccharomyces pombe 456216 R-SPO-380927 https://reactome.org/PathwayBrowser/#/R-SPO-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Schizosaccharomyces pombe 456216 R-SPO-381091 https://reactome.org/PathwayBrowser/#/R-SPO-381091 IRE1 dimer autophosphorylates IEA Schizosaccharomyces pombe 456216 R-SPO-382560 https://reactome.org/PathwayBrowser/#/R-SPO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Schizosaccharomyces pombe 456216 R-SPO-391266 https://reactome.org/PathwayBrowser/#/R-SPO-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Schizosaccharomyces pombe 456216 R-SPO-428273 https://reactome.org/PathwayBrowser/#/R-SPO-428273 SPHK1 phosphorylates sphingoid IEA Schizosaccharomyces pombe 456216 R-SPO-428941 https://reactome.org/PathwayBrowser/#/R-SPO-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Schizosaccharomyces pombe 456216 R-SPO-428961 https://reactome.org/PathwayBrowser/#/R-SPO-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Schizosaccharomyces pombe 456216 R-SPO-442749 https://reactome.org/PathwayBrowser/#/R-SPO-442749 CaMKK autophosphorylates in the nucleus IEA Schizosaccharomyces pombe 456216 R-SPO-445079 https://reactome.org/PathwayBrowser/#/R-SPO-445079 Phosphorylation of L1 by ERK IEA Schizosaccharomyces pombe 456216 R-SPO-448955 https://reactome.org/PathwayBrowser/#/R-SPO-448955 Phosphorylation of MEF2 proteins by p38 IEA Schizosaccharomyces pombe 456216 R-SPO-450490 https://reactome.org/PathwayBrowser/#/R-SPO-450490 Protein Kinase B/Akt phosphorylates BRF1 IEA Schizosaccharomyces pombe 456216 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 456216 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 456216 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 456216 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 456216 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 456216 R-SPO-504054 https://reactome.org/PathwayBrowser/#/R-SPO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Schizosaccharomyces pombe 456216 R-SPO-508040 https://reactome.org/PathwayBrowser/#/R-SPO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Schizosaccharomyces pombe 456216 R-SPO-5082405 https://reactome.org/PathwayBrowser/#/R-SPO-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Schizosaccharomyces pombe 456216 R-SPO-5218805 https://reactome.org/PathwayBrowser/#/R-SPO-5218805 PKC autophosphorylates IEA Schizosaccharomyces pombe 456216 R-SPO-5218821 https://reactome.org/PathwayBrowser/#/R-SPO-5218821 PDK1 phosphorylates PKC IEA Schizosaccharomyces pombe 456216 R-SPO-5218823 https://reactome.org/PathwayBrowser/#/R-SPO-5218823 PKC phosphorylates sphingosine kinase 1 IEA Schizosaccharomyces pombe 456216 R-SPO-5223317 https://reactome.org/PathwayBrowser/#/R-SPO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 456216 R-SPO-5251955 https://reactome.org/PathwayBrowser/#/R-SPO-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Schizosaccharomyces pombe 456216 R-SPO-5251959 https://reactome.org/PathwayBrowser/#/R-SPO-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Schizosaccharomyces pombe 456216 R-SPO-5251989 https://reactome.org/PathwayBrowser/#/R-SPO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Schizosaccharomyces pombe 456216 R-SPO-5252079 https://reactome.org/PathwayBrowser/#/R-SPO-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Schizosaccharomyces pombe 456216 R-SPO-5358513 https://reactome.org/PathwayBrowser/#/R-SPO-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Schizosaccharomyces pombe 456216 R-SPO-5358525 https://reactome.org/PathwayBrowser/#/R-SPO-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Schizosaccharomyces pombe 456216 R-SPO-5358912 https://reactome.org/PathwayBrowser/#/R-SPO-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Schizosaccharomyces pombe 456216 R-SPO-5444511 https://reactome.org/PathwayBrowser/#/R-SPO-5444511 Formation of MSH2:MSH3 Complex IEA Schizosaccharomyces pombe 456216 R-SPO-5444516 https://reactome.org/PathwayBrowser/#/R-SPO-5444516 Formation of MSH2:MSH6 Complex IEA Schizosaccharomyces pombe 456216 R-SPO-5618107 https://reactome.org/PathwayBrowser/#/R-SPO-5618107 ATP binding to HSP90 triggers conformation change IEA Schizosaccharomyces pombe 456216 R-SPO-5623667 https://reactome.org/PathwayBrowser/#/R-SPO-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Schizosaccharomyces pombe 456216 R-SPO-5625784 https://reactome.org/PathwayBrowser/#/R-SPO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 456216 R-SPO-5627775 https://reactome.org/PathwayBrowser/#/R-SPO-5627775 Autophosphorylation of PAK1,2,3 IEA Schizosaccharomyces pombe 456216 R-SPO-5654989 https://reactome.org/PathwayBrowser/#/R-SPO-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Schizosaccharomyces pombe 456216 R-SPO-5662466 https://reactome.org/PathwayBrowser/#/R-SPO-5662466 XYLB phosphorylates D-xylulose IEA Schizosaccharomyces pombe 456216 R-SPO-5665868 https://reactome.org/PathwayBrowser/#/R-SPO-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Schizosaccharomyces pombe 456216 R-SPO-5668932 https://reactome.org/PathwayBrowser/#/R-SPO-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Schizosaccharomyces pombe 456216 R-SPO-5671749 https://reactome.org/PathwayBrowser/#/R-SPO-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Schizosaccharomyces pombe 456216 R-SPO-5672008 https://reactome.org/PathwayBrowser/#/R-SPO-5672008 Thr-180 of ULK1 is phosphorylated IEA Schizosaccharomyces pombe 456216 R-SPO-5672012 https://reactome.org/PathwayBrowser/#/R-SPO-5672012 Beclin-1 complex phosphorylates PtdIns IEA Schizosaccharomyces pombe 456216 R-SPO-5674373 https://reactome.org/PathwayBrowser/#/R-SPO-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Schizosaccharomyces pombe 456216 R-SPO-5674496 https://reactome.org/PathwayBrowser/#/R-SPO-5674496 Activated MAPKs phosphorylate MAP2K1 IEA Schizosaccharomyces pombe 456216 R-SPO-5675868 https://reactome.org/PathwayBrowser/#/R-SPO-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Schizosaccharomyces pombe 456216 R-SPO-5678706 https://reactome.org/PathwayBrowser/#/R-SPO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Schizosaccharomyces pombe 456216 R-SPO-5679041 https://reactome.org/PathwayBrowser/#/R-SPO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Schizosaccharomyces pombe 456216 R-SPO-5679205 https://reactome.org/PathwayBrowser/#/R-SPO-5679205 ULK1 phosphorylates Beclin-1 IEA Schizosaccharomyces pombe 456216 R-SPO-5682026 https://reactome.org/PathwayBrowser/#/R-SPO-5682026 MRN bound to shortened telomeres activates ATM IEA Schizosaccharomyces pombe 456216 R-SPO-5682598 https://reactome.org/PathwayBrowser/#/R-SPO-5682598 ATM phosphorylates HERC2 IEA Schizosaccharomyces pombe 456216 R-SPO-5682983 https://reactome.org/PathwayBrowser/#/R-SPO-5682983 ATM phosphorylates WHSC1 IEA Schizosaccharomyces pombe 456216 R-SPO-5683425 https://reactome.org/PathwayBrowser/#/R-SPO-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Schizosaccharomyces pombe 456216 R-SPO-5683792 https://reactome.org/PathwayBrowser/#/R-SPO-5683792 p-T68-CHEK2 autophosphorylates IEA Schizosaccharomyces pombe 456216 R-SPO-5684096 https://reactome.org/PathwayBrowser/#/R-SPO-5684096 CDK2 phosphorylates RBBP8 IEA Schizosaccharomyces pombe 456216 R-SPO-5684140 https://reactome.org/PathwayBrowser/#/R-SPO-5684140 ATM phosphorylates RBBP8 IEA Schizosaccharomyces pombe 456216 R-SPO-5685230 https://reactome.org/PathwayBrowser/#/R-SPO-5685230 CHEK1 phosphorylates RAD51 IEA Schizosaccharomyces pombe 456216 R-SPO-5687086 https://reactome.org/PathwayBrowser/#/R-SPO-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Schizosaccharomyces pombe 456216 R-SPO-5690996 https://reactome.org/PathwayBrowser/#/R-SPO-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Schizosaccharomyces pombe 456216 R-SPO-5692462 https://reactome.org/PathwayBrowser/#/R-SPO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Schizosaccharomyces pombe 456216 R-SPO-5692480 https://reactome.org/PathwayBrowser/#/R-SPO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 456216 R-SPO-5693536 https://reactome.org/PathwayBrowser/#/R-SPO-5693536 ATM phosphorylates MDC1 IEA Schizosaccharomyces pombe 456216 R-SPO-5693540 https://reactome.org/PathwayBrowser/#/R-SPO-5693540 MRN activates ATM IEA Schizosaccharomyces pombe 456216 R-SPO-5693549 https://reactome.org/PathwayBrowser/#/R-SPO-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Schizosaccharomyces pombe 456216 R-SPO-5693598 https://reactome.org/PathwayBrowser/#/R-SPO-5693598 ATM phosphorylates NBN IEA Schizosaccharomyces pombe 456216 R-SPO-5694441 https://reactome.org/PathwayBrowser/#/R-SPO-5694441 CSNK1D phosphorylates SEC23 IEA Schizosaccharomyces pombe 456216 R-SPO-5696074 https://reactome.org/PathwayBrowser/#/R-SPO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Schizosaccharomyces pombe 456216 R-SPO-5696839 https://reactome.org/PathwayBrowser/#/R-SPO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Schizosaccharomyces pombe 456216 R-SPO-6782131 https://reactome.org/PathwayBrowser/#/R-SPO-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Schizosaccharomyces pombe 456216 R-SPO-6788810 https://reactome.org/PathwayBrowser/#/R-SPO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Schizosaccharomyces pombe 456216 R-SPO-6795290 https://reactome.org/PathwayBrowser/#/R-SPO-6795290 TORC2 complex phosphorylates SGK1 IEA Schizosaccharomyces pombe 456216 R-SPO-6795473 https://reactome.org/PathwayBrowser/#/R-SPO-6795473 PDPK1 phosphorylates SGK1 IEA Schizosaccharomyces pombe 456216 R-SPO-6797606 https://reactome.org/PathwayBrowser/#/R-SPO-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Schizosaccharomyces pombe 456216 R-SPO-6798174 https://reactome.org/PathwayBrowser/#/R-SPO-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Schizosaccharomyces pombe 456216 R-SPO-6798372 https://reactome.org/PathwayBrowser/#/R-SPO-6798372 ATM phosphorylates DYRK2 IEA Schizosaccharomyces pombe 456216 R-SPO-6801342 https://reactome.org/PathwayBrowser/#/R-SPO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Schizosaccharomyces pombe 456216 R-SPO-6801456 https://reactome.org/PathwayBrowser/#/R-SPO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Schizosaccharomyces pombe 456216 R-SPO-6802973 https://reactome.org/PathwayBrowser/#/R-SPO-6802973 PLK3 phosphorylates CDC25C IEA Schizosaccharomyces pombe 456216 R-SPO-6805640 https://reactome.org/PathwayBrowser/#/R-SPO-6805640 AKT phosphorylates KAT6A IEA Schizosaccharomyces pombe 456216 R-SPO-6806877 https://reactome.org/PathwayBrowser/#/R-SPO-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Schizosaccharomyces pombe 456216 R-SPO-6806967 https://reactome.org/PathwayBrowser/#/R-SPO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Schizosaccharomyces pombe 456216 R-SPO-6807868 https://reactome.org/PathwayBrowser/#/R-SPO-6807868 GBF1 stimulates ARF nucleotide exchange IEA Schizosaccharomyces pombe 456216 R-SPO-6810233 https://reactome.org/PathwayBrowser/#/R-SPO-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Schizosaccharomyces pombe 456216 R-SPO-6811522 https://reactome.org/PathwayBrowser/#/R-SPO-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Schizosaccharomyces pombe 456216 R-SPO-6814119 https://reactome.org/PathwayBrowser/#/R-SPO-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Schizosaccharomyces pombe 456216 R-SPO-6814120 https://reactome.org/PathwayBrowser/#/R-SPO-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Schizosaccharomyces pombe 456216 R-SPO-6814124 https://reactome.org/PathwayBrowser/#/R-SPO-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Schizosaccharomyces pombe 456216 R-SPO-68944 https://reactome.org/PathwayBrowser/#/R-SPO-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Schizosaccharomyces pombe 456216 R-SPO-68954 https://reactome.org/PathwayBrowser/#/R-SPO-68954 Mcm2-7 is phosphorylated by DDK IEA Schizosaccharomyces pombe 456216 R-SPO-69005 https://reactome.org/PathwayBrowser/#/R-SPO-69005 Cdc6 protein is phosphorylated by CDK IEA Schizosaccharomyces pombe 456216 R-SPO-69063 https://reactome.org/PathwayBrowser/#/R-SPO-69063 Loading of PCNA - Sliding Clamp Formation IEA Schizosaccharomyces pombe 456216 R-SPO-69604 https://reactome.org/PathwayBrowser/#/R-SPO-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Schizosaccharomyces pombe 456216 R-SPO-69608 https://reactome.org/PathwayBrowser/#/R-SPO-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Schizosaccharomyces pombe 456216 R-SPO-70349 https://reactome.org/PathwayBrowser/#/R-SPO-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Schizosaccharomyces pombe 456216 R-SPO-70420 https://reactome.org/PathwayBrowser/#/R-SPO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Schizosaccharomyces pombe 456216 R-SPO-70467 https://reactome.org/PathwayBrowser/#/R-SPO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 456216 R-SPO-70486 https://reactome.org/PathwayBrowser/#/R-SPO-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Schizosaccharomyces pombe 456216 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 456216 R-SPO-70555 https://reactome.org/PathwayBrowser/#/R-SPO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Schizosaccharomyces pombe 456216 R-SPO-70606 https://reactome.org/PathwayBrowser/#/R-SPO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Schizosaccharomyces pombe 456216 R-SPO-70967 https://reactome.org/PathwayBrowser/#/R-SPO-70967 IDH3 complex decarboxylates isocitrate IEA Schizosaccharomyces pombe 456216 R-SPO-70997 https://reactome.org/PathwayBrowser/#/R-SPO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Schizosaccharomyces pombe 456216 R-SPO-71401 https://reactome.org/PathwayBrowser/#/R-SPO-71401 OGDH dimer decarboxylates 2-OG IEA Schizosaccharomyces pombe 456216 R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 456216 R-SPO-71802 https://reactome.org/PathwayBrowser/#/R-SPO-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 456216 R-SPO-71850 https://reactome.org/PathwayBrowser/#/R-SPO-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Schizosaccharomyces pombe 456216 R-SPO-72621 https://reactome.org/PathwayBrowser/#/R-SPO-72621 Ribosomal scanning IEA Schizosaccharomyces pombe 456216 R-SPO-72647 https://reactome.org/PathwayBrowser/#/R-SPO-72647 Cap-bound mRNA is activated by helicases IEA Schizosaccharomyces pombe 456216 R-SPO-73548 https://reactome.org/PathwayBrowser/#/R-SPO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Schizosaccharomyces pombe 456216 R-SPO-73577 https://reactome.org/PathwayBrowser/#/R-SPO-73577 CAD hexamer transforms L-Gln to CAP IEA Schizosaccharomyces pombe 456216 R-SPO-73635 https://reactome.org/PathwayBrowser/#/R-SPO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Schizosaccharomyces pombe 456216 R-SPO-73647 https://reactome.org/PathwayBrowser/#/R-SPO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Schizosaccharomyces pombe 456216 R-SPO-73788 https://reactome.org/PathwayBrowser/#/R-SPO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Schizosaccharomyces pombe 456216 R-SPO-73810 https://reactome.org/PathwayBrowser/#/R-SPO-73810 FGAM + ATP => AIR + ADP + Pi IEA Schizosaccharomyces pombe 456216 R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 456216 R-SPO-73814 https://reactome.org/PathwayBrowser/#/R-SPO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Schizosaccharomyces pombe 456216 R-SPO-75010 https://reactome.org/PathwayBrowser/#/R-SPO-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Schizosaccharomyces pombe 456216 R-SPO-75040 https://reactome.org/PathwayBrowser/#/R-SPO-75040 Phosphorylation of Wee1 kinase by Chk1 TAS Schizosaccharomyces pombe 456216 R-SPO-75125 https://reactome.org/PathwayBrowser/#/R-SPO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Schizosaccharomyces pombe 456216 R-SPO-75126 https://reactome.org/PathwayBrowser/#/R-SPO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Schizosaccharomyces pombe 456216 R-SPO-75809 https://reactome.org/PathwayBrowser/#/R-SPO-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Schizosaccharomyces pombe 456216 R-SPO-75848 https://reactome.org/PathwayBrowser/#/R-SPO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Schizosaccharomyces pombe 456216 R-SPO-75851 https://reactome.org/PathwayBrowser/#/R-SPO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 456216 R-SPO-75949 https://reactome.org/PathwayBrowser/#/R-SPO-75949 RNA Polymerase II Promoter Opening: First Transition IEA Schizosaccharomyces pombe 456216 R-SPO-77071 https://reactome.org/PathwayBrowser/#/R-SPO-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Schizosaccharomyces pombe 456216 R-SPO-8847638 https://reactome.org/PathwayBrowser/#/R-SPO-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Schizosaccharomyces pombe 456216 R-SPO-8850945 https://reactome.org/PathwayBrowser/#/R-SPO-8850945 Casein kinase II phosphorylates PTEN IEA Schizosaccharomyces pombe 456216 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 456216 R-SPO-8856813 https://reactome.org/PathwayBrowser/#/R-SPO-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Schizosaccharomyces pombe 456216 R-SPO-8868066 https://reactome.org/PathwayBrowser/#/R-SPO-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Schizosaccharomyces pombe 456216 R-SPO-8876446 https://reactome.org/PathwayBrowser/#/R-SPO-8876446 p-ULK1 phosphorylates DENND3 IEA Schizosaccharomyces pombe 456216 R-SPO-8876889 https://reactome.org/PathwayBrowser/#/R-SPO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 456216 R-SPO-8942836 https://reactome.org/PathwayBrowser/#/R-SPO-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Schizosaccharomyces pombe 456216 R-SPO-8948039 https://reactome.org/PathwayBrowser/#/R-SPO-8948039 FUNDC1 is phosphorylated by CK2 IEA Schizosaccharomyces pombe 456216 R-SPO-8948146 https://reactome.org/PathwayBrowser/#/R-SPO-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Schizosaccharomyces pombe 456216 R-SPO-8948757 https://reactome.org/PathwayBrowser/#/R-SPO-8948757 AKT phosphorylates MKRN1 IEA Schizosaccharomyces pombe 456216 R-SPO-8954327 https://reactome.org/PathwayBrowser/#/R-SPO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Schizosaccharomyces pombe 456216 R-SPO-8955844 https://reactome.org/PathwayBrowser/#/R-SPO-8955844 RBKS phosphorylates ribose to R5P IEA Schizosaccharomyces pombe 456216 R-SPO-9008043 https://reactome.org/PathwayBrowser/#/R-SPO-9008043 MAPK8 phosphorylation IEA Schizosaccharomyces pombe 456216 R-SPO-9012319 https://reactome.org/PathwayBrowser/#/R-SPO-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Schizosaccharomyces pombe 456216 R-SPO-917693 https://reactome.org/PathwayBrowser/#/R-SPO-917693 ESCRT Disassembly IEA Schizosaccharomyces pombe 456216 R-SPO-917841 https://reactome.org/PathwayBrowser/#/R-SPO-917841 Acidification of Tf:TfR1 containing endosome IEA Schizosaccharomyces pombe 456216 R-SPO-927889 https://reactome.org/PathwayBrowser/#/R-SPO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Schizosaccharomyces pombe 456216 R-SPO-936883 https://reactome.org/PathwayBrowser/#/R-SPO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Schizosaccharomyces pombe 456216 R-SPO-936895 https://reactome.org/PathwayBrowser/#/R-SPO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Schizosaccharomyces pombe 456216 R-SPO-939763 https://reactome.org/PathwayBrowser/#/R-SPO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Schizosaccharomyces pombe 456216 R-SPO-947591 https://reactome.org/PathwayBrowser/#/R-SPO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Schizosaccharomyces pombe 456216 R-SPO-9606884 https://reactome.org/PathwayBrowser/#/R-SPO-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Schizosaccharomyces pombe 456216 R-SPO-9612509 https://reactome.org/PathwayBrowser/#/R-SPO-9612509 SGK phosphorylates SRF IEA Schizosaccharomyces pombe 456216 R-SPO-9619355 https://reactome.org/PathwayBrowser/#/R-SPO-9619355 CaMKK autophosphorylates in the cytosol IEA Schizosaccharomyces pombe 456216 R-SPO-9626817 https://reactome.org/PathwayBrowser/#/R-SPO-9626817 PKC phosphorylates NCF1 IEA Schizosaccharomyces pombe 456216 R-SPO-9626832 https://reactome.org/PathwayBrowser/#/R-SPO-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Schizosaccharomyces pombe 456216 R-SPO-9626880 https://reactome.org/PathwayBrowser/#/R-SPO-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Schizosaccharomyces pombe 456216 R-SPO-9632858 https://reactome.org/PathwayBrowser/#/R-SPO-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Schizosaccharomyces pombe 456216 R-SPO-964958 https://reactome.org/PathwayBrowser/#/R-SPO-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Schizosaccharomyces pombe 456216 R-SPO-964962 https://reactome.org/PathwayBrowser/#/R-SPO-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Schizosaccharomyces pombe 456216 R-SPO-964970 https://reactome.org/PathwayBrowser/#/R-SPO-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Schizosaccharomyces pombe 456216 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 456216 R-SPO-9684118 https://reactome.org/PathwayBrowser/#/R-SPO-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Schizosaccharomyces pombe 456216 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 456216 R-SPO-9734687 https://reactome.org/PathwayBrowser/#/R-SPO-9734687 ORC6 is phosphorylated on T195 IEA Schizosaccharomyces pombe 456216 R-SPO-9748949 https://reactome.org/PathwayBrowser/#/R-SPO-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Schizosaccharomyces pombe 456216 R-SPO-9748963 https://reactome.org/PathwayBrowser/#/R-SPO-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Schizosaccharomyces pombe 456216 R-SPO-9748969 https://reactome.org/PathwayBrowser/#/R-SPO-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Schizosaccharomyces pombe 456216 R-SPO-9748999 https://reactome.org/PathwayBrowser/#/R-SPO-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Schizosaccharomyces pombe 456216 R-SPO-9750656 https://reactome.org/PathwayBrowser/#/R-SPO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Schizosaccharomyces pombe 456216 R-SPO-9753278 https://reactome.org/PathwayBrowser/#/R-SPO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 456216 R-SPO-9753283 https://reactome.org/PathwayBrowser/#/R-SPO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 456216 R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 456216 R-SPO-9754974 https://reactome.org/PathwayBrowser/#/R-SPO-9754974 ADK phosphorylates RBV IEA Schizosaccharomyces pombe 456216 R-SPO-9755013 https://reactome.org/PathwayBrowser/#/R-SPO-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Schizosaccharomyces pombe 456216 R-SPO-9759454 https://reactome.org/PathwayBrowser/#/R-SPO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Schizosaccharomyces pombe 456216 R-SPO-9759461 https://reactome.org/PathwayBrowser/#/R-SPO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Schizosaccharomyces pombe 456216 R-SPO-9760094 https://reactome.org/PathwayBrowser/#/R-SPO-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Schizosaccharomyces pombe 456216 R-SPO-983144 https://reactome.org/PathwayBrowser/#/R-SPO-983144 Transport of Antigen peptide in to ER IEA Schizosaccharomyces pombe 456216 R-SPO-9837337 https://reactome.org/PathwayBrowser/#/R-SPO-9837337 DCAKD phosphorylates DP-CoA IEA Schizosaccharomyces pombe 456216 R-SPO-9838004 https://reactome.org/PathwayBrowser/#/R-SPO-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 456216 R-SPO-9838081 https://reactome.org/PathwayBrowser/#/R-SPO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Schizosaccharomyces pombe 456216 R-SPO-9838321 https://reactome.org/PathwayBrowser/#/R-SPO-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Schizosaccharomyces pombe 456216 R-SPO-9839105 https://reactome.org/PathwayBrowser/#/R-SPO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Schizosaccharomyces pombe 456216 R-SPO-9839113 https://reactome.org/PathwayBrowser/#/R-SPO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 456216 R-SPO-9843721 https://reactome.org/PathwayBrowser/#/R-SPO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Schizosaccharomyces pombe 456216 R-SSC-1008248 https://reactome.org/PathwayBrowser/#/R-SSC-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Sus scrofa 456216 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 456216 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 456216 R-SSC-109415 https://reactome.org/PathwayBrowser/#/R-SSC-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Sus scrofa 456216 R-SSC-109624 https://reactome.org/PathwayBrowser/#/R-SSC-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Sus scrofa 456216 R-SSC-109699 https://reactome.org/PathwayBrowser/#/R-SSC-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-109702 https://reactome.org/PathwayBrowser/#/R-SSC-109702 PDPK1 phosphorylates AKT2 IEA Sus scrofa 456216 R-SSC-109759 https://reactome.org/PathwayBrowser/#/R-SSC-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Sus scrofa 456216 R-SSC-109822 https://reactome.org/PathwayBrowser/#/R-SSC-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Sus scrofa 456216 R-SSC-109823 https://reactome.org/PathwayBrowser/#/R-SSC-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Sus scrofa 456216 R-SSC-109862 https://reactome.org/PathwayBrowser/#/R-SSC-109862 MAP2K2 phosphorylates MAPK1 IEA Sus scrofa 456216 R-SSC-109903 https://reactome.org/PathwayBrowser/#/R-SSC-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Sus scrofa 456216 R-SSC-110133 https://reactome.org/PathwayBrowser/#/R-SSC-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Sus scrofa 456216 R-SSC-110137 https://reactome.org/PathwayBrowser/#/R-SSC-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Sus scrofa 456216 R-SSC-110138 https://reactome.org/PathwayBrowser/#/R-SSC-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 456216 R-SSC-110141 https://reactome.org/PathwayBrowser/#/R-SSC-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Sus scrofa 456216 R-SSC-110144 https://reactome.org/PathwayBrowser/#/R-SSC-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Sus scrofa 456216 R-SSC-110145 https://reactome.org/PathwayBrowser/#/R-SSC-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Sus scrofa 456216 R-SSC-1112510 https://reactome.org/PathwayBrowser/#/R-SSC-1112510 IL6ST is tyrosine phosphorylated IEA Sus scrofa 456216 R-SSC-1112514 https://reactome.org/PathwayBrowser/#/R-SSC-1112514 JAK activation IEA Sus scrofa 456216 R-SSC-1112602 https://reactome.org/PathwayBrowser/#/R-SSC-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Sus scrofa 456216 R-SSC-1112703 https://reactome.org/PathwayBrowser/#/R-SSC-1112703 PTPN11 is phosphorylated IEA Sus scrofa 456216 R-SSC-1112727 https://reactome.org/PathwayBrowser/#/R-SSC-1112727 Serine phosphorylation of STATs IEA Sus scrofa 456216 R-SSC-111898 https://reactome.org/PathwayBrowser/#/R-SSC-111898 Phosphorylation of cPLA2 by ERK-2 IEA Sus scrofa 456216 R-SSC-111970 https://reactome.org/PathwayBrowser/#/R-SSC-111970 PKC phosphorylates GRK2 IEA Sus scrofa 456216 R-SSC-112381 https://reactome.org/PathwayBrowser/#/R-SSC-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Sus scrofa 456216 R-SSC-114252 https://reactome.org/PathwayBrowser/#/R-SSC-114252 Cleavage of Procaspase-3 by the apoptosome IEA Sus scrofa 456216 R-SSC-114254 https://reactome.org/PathwayBrowser/#/R-SSC-114254 CYCS binds to APAF1 IEA Sus scrofa 456216 R-SSC-114259 https://reactome.org/PathwayBrowser/#/R-SSC-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Sus scrofa 456216 R-SSC-114261 https://reactome.org/PathwayBrowser/#/R-SSC-114261 Cleavage of Procaspase-7 by the apoptosome IEA Sus scrofa 456216 R-SSC-114600 https://reactome.org/PathwayBrowser/#/R-SSC-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Sus scrofa 456216 R-SSC-114683 https://reactome.org/PathwayBrowser/#/R-SSC-114683 Phosphorylation of Platelet Sec-1 IEA Sus scrofa 456216 R-SSC-114684 https://reactome.org/PathwayBrowser/#/R-SSC-114684 Phosphorylation of Syntaxin-4 IEA Sus scrofa 456216 R-SSC-1168459 https://reactome.org/PathwayBrowser/#/R-SSC-1168459 Lyn activates ERK IEA Sus scrofa 456216 R-SSC-1168638 https://reactome.org/PathwayBrowser/#/R-SSC-1168638 Activated IKK phosphorylates I-kappaB IEA Sus scrofa 456216 R-SSC-1181149 https://reactome.org/PathwayBrowser/#/R-SSC-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Sus scrofa 456216 R-SSC-1226094 https://reactome.org/PathwayBrowser/#/R-SSC-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Sus scrofa 456216 R-SSC-1226095 https://reactome.org/PathwayBrowser/#/R-SSC-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Sus scrofa 456216 R-SSC-1247935 https://reactome.org/PathwayBrowser/#/R-SSC-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Sus scrofa 456216 R-SSC-1247960 https://reactome.org/PathwayBrowser/#/R-SSC-1247960 Activation of p38 MAPK IEA Sus scrofa 456216 R-SSC-1250195 https://reactome.org/PathwayBrowser/#/R-SSC-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Sus scrofa 456216 R-SSC-1250315 https://reactome.org/PathwayBrowser/#/R-SSC-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Sus scrofa 456216 R-SSC-1250348 https://reactome.org/PathwayBrowser/#/R-SSC-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Sus scrofa 456216 R-SSC-1250370 https://reactome.org/PathwayBrowser/#/R-SSC-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Sus scrofa 456216 R-SSC-1250462 https://reactome.org/PathwayBrowser/#/R-SSC-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Sus scrofa 456216 R-SSC-1295540 https://reactome.org/PathwayBrowser/#/R-SSC-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Sus scrofa 456216 R-SSC-1295609 https://reactome.org/PathwayBrowser/#/R-SSC-1295609 SRC phosphorylates SPRY2 on Y55 and Y227 IEA Sus scrofa 456216 R-SSC-1306957 https://reactome.org/PathwayBrowser/#/R-SSC-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Sus scrofa 456216 R-SSC-1306979 https://reactome.org/PathwayBrowser/#/R-SSC-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Sus scrofa 456216 R-SSC-1307963 https://reactome.org/PathwayBrowser/#/R-SSC-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Sus scrofa 456216 R-SSC-1362270 https://reactome.org/PathwayBrowser/#/R-SSC-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Sus scrofa 456216 R-SSC-1369028 https://reactome.org/PathwayBrowser/#/R-SSC-1369028 ABCAs mediate lipid efflux IEA Sus scrofa 456216 R-SSC-1369052 https://reactome.org/PathwayBrowser/#/R-SSC-1369052 ABCAs mediate lipid influx IEA Sus scrofa 456216 R-SSC-1369065 https://reactome.org/PathwayBrowser/#/R-SSC-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Sus scrofa 456216 R-SSC-1370505 https://reactome.org/PathwayBrowser/#/R-SSC-1370505 PRLR is phosphorylated at Ser-349 IEA Sus scrofa 456216 R-SSC-139908 https://reactome.org/PathwayBrowser/#/R-SSC-139908 Phosphorylation of DLC2 by MAPK8 IEA Sus scrofa 456216 R-SSC-139918 https://reactome.org/PathwayBrowser/#/R-SSC-139918 Phosphorylation of BIM by JNK IEA Sus scrofa 456216 R-SSC-1433418 https://reactome.org/PathwayBrowser/#/R-SSC-1433418 Phosphorylation of JAK2 IEA Sus scrofa 456216 R-SSC-1433454 https://reactome.org/PathwayBrowser/#/R-SSC-1433454 Phosphorylation of GAB2 by SFKs IEA Sus scrofa 456216 R-SSC-1433488 https://reactome.org/PathwayBrowser/#/R-SSC-1433488 Phosphorylation of SHP2 by SFKs IEA Sus scrofa 456216 R-SSC-1433506 https://reactome.org/PathwayBrowser/#/R-SSC-1433506 Phosphorylation of APS IEA Sus scrofa 456216 R-SSC-1433508 https://reactome.org/PathwayBrowser/#/R-SSC-1433508 PKC alpha interacts with and phosphorylates KIT IEA Sus scrofa 456216 R-SSC-1433514 https://reactome.org/PathwayBrowser/#/R-SSC-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Sus scrofa 456216 R-SSC-1433542 https://reactome.org/PathwayBrowser/#/R-SSC-1433542 Phosphorylation and activation of VAV1 IEA Sus scrofa 456216 R-SSC-1454916 https://reactome.org/PathwayBrowser/#/R-SSC-1454916 The ABCC family mediates organic anion transport IEA Sus scrofa 456216 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-1467466 https://reactome.org/PathwayBrowser/#/R-SSC-1467466 ABCA4 mediates atRAL transport IEA Sus scrofa 456216 R-SSC-1470009 https://reactome.org/PathwayBrowser/#/R-SSC-1470009 Phosphorylation of STATs IEA Sus scrofa 456216 R-SSC-1472121 https://reactome.org/PathwayBrowser/#/R-SSC-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Sus scrofa 456216 R-SSC-1475422 https://reactome.org/PathwayBrowser/#/R-SSC-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Sus scrofa 456216 R-SSC-1483004 https://reactome.org/PathwayBrowser/#/R-SSC-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Sus scrofa 456216 R-SSC-1483222 https://reactome.org/PathwayBrowser/#/R-SSC-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Sus scrofa 456216 R-SSC-1497853 https://reactome.org/PathwayBrowser/#/R-SSC-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Sus scrofa 456216 R-SSC-1524186 https://reactome.org/PathwayBrowser/#/R-SSC-1524186 Phosphorylation of PLCgamma by PDGFR IEA Sus scrofa 456216 R-SSC-1549526 https://reactome.org/PathwayBrowser/#/R-SSC-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Sus scrofa 456216 R-SSC-156673 https://reactome.org/PathwayBrowser/#/R-SSC-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Sus scrofa 456216 R-SSC-156678 https://reactome.org/PathwayBrowser/#/R-SSC-156678 Activation of Cdc25C IEA Sus scrofa 456216 R-SSC-156682 https://reactome.org/PathwayBrowser/#/R-SSC-156682 PLK1 phosphorylates NUDC IEA Sus scrofa 456216 R-SSC-156699 https://reactome.org/PathwayBrowser/#/R-SSC-156699 Inactivation of Wee1 kinase IEA Sus scrofa 456216 R-SSC-156723 https://reactome.org/PathwayBrowser/#/R-SSC-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Sus scrofa 456216 R-SSC-159101 https://reactome.org/PathwayBrowser/#/R-SSC-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Sus scrofa 456216 R-SSC-162657 https://reactome.org/PathwayBrowser/#/R-SSC-162657 Inactivation of Myt1 kinase IEA Sus scrofa 456216 R-SSC-163010 https://reactome.org/PathwayBrowser/#/R-SSC-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Sus scrofa 456216 R-SSC-163120 https://reactome.org/PathwayBrowser/#/R-SSC-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Sus scrofa 456216 R-SSC-163215 https://reactome.org/PathwayBrowser/#/R-SSC-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Sus scrofa 456216 R-SSC-1632857 https://reactome.org/PathwayBrowser/#/R-SSC-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Sus scrofa 456216 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa 456216 R-SSC-1638845 https://reactome.org/PathwayBrowser/#/R-SSC-1638845 CERK phosphorylates CERA to form C1P IEA Sus scrofa 456216 R-SSC-164832 https://reactome.org/PathwayBrowser/#/R-SSC-164832 ATPase synthesizes ATP IEA Sus scrofa 456216 R-SSC-164840 https://reactome.org/PathwayBrowser/#/R-SSC-164840 ADP and Pi bind to ATPase IEA Sus scrofa 456216 R-SSC-165162 https://reactome.org/PathwayBrowser/#/R-SSC-165162 Phosphorylation of TSC2 by PKB IEA Sus scrofa 456216 R-SSC-165182 https://reactome.org/PathwayBrowser/#/R-SSC-165182 Phosphorylation of complexed TSC2 by PKB IEA Sus scrofa 456216 R-SSC-165692 https://reactome.org/PathwayBrowser/#/R-SSC-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Sus scrofa 456216 R-SSC-165718 https://reactome.org/PathwayBrowser/#/R-SSC-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Sus scrofa 456216 R-SSC-165726 https://reactome.org/PathwayBrowser/#/R-SSC-165726 Phosphorylation of Ribosomal protein S6 by activated S6K1 IEA Sus scrofa 456216 R-SSC-165758 https://reactome.org/PathwayBrowser/#/R-SSC-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Sus scrofa 456216 R-SSC-165766 https://reactome.org/PathwayBrowser/#/R-SSC-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Sus scrofa 456216 R-SSC-165777 https://reactome.org/PathwayBrowser/#/R-SSC-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Sus scrofa 456216 R-SSC-166245 https://reactome.org/PathwayBrowser/#/R-SSC-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Sus scrofa 456216 R-SSC-1675773 https://reactome.org/PathwayBrowser/#/R-SSC-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Sus scrofa 456216 R-SSC-1675776 https://reactome.org/PathwayBrowser/#/R-SSC-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Sus scrofa 456216 R-SSC-1675780 https://reactome.org/PathwayBrowser/#/R-SSC-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Sus scrofa 456216 R-SSC-1675810 https://reactome.org/PathwayBrowser/#/R-SSC-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Sus scrofa 456216 R-SSC-1675813 https://reactome.org/PathwayBrowser/#/R-SSC-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Sus scrofa 456216 R-SSC-1675883 https://reactome.org/PathwayBrowser/#/R-SSC-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Sus scrofa 456216 R-SSC-1675928 https://reactome.org/PathwayBrowser/#/R-SSC-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Sus scrofa 456216 R-SSC-1675939 https://reactome.org/PathwayBrowser/#/R-SSC-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Sus scrofa 456216 R-SSC-1675961 https://reactome.org/PathwayBrowser/#/R-SSC-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Sus scrofa 456216 R-SSC-1675974 https://reactome.org/PathwayBrowser/#/R-SSC-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Sus scrofa 456216 R-SSC-1676024 https://reactome.org/PathwayBrowser/#/R-SSC-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Sus scrofa 456216 R-SSC-1676048 https://reactome.org/PathwayBrowser/#/R-SSC-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Sus scrofa 456216 R-SSC-1676082 https://reactome.org/PathwayBrowser/#/R-SSC-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Sus scrofa 456216 R-SSC-1676109 https://reactome.org/PathwayBrowser/#/R-SSC-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Sus scrofa 456216 R-SSC-1676134 https://reactome.org/PathwayBrowser/#/R-SSC-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Sus scrofa 456216 R-SSC-1676145 https://reactome.org/PathwayBrowser/#/R-SSC-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Sus scrofa 456216 R-SSC-1676185 https://reactome.org/PathwayBrowser/#/R-SSC-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Sus scrofa 456216 R-SSC-1676206 https://reactome.org/PathwayBrowser/#/R-SSC-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Sus scrofa 456216 R-SSC-1678944 https://reactome.org/PathwayBrowser/#/R-SSC-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Sus scrofa 456216 R-SSC-168053 https://reactome.org/PathwayBrowser/#/R-SSC-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Sus scrofa 456216 R-SSC-168136 https://reactome.org/PathwayBrowser/#/R-SSC-168136 Activated JNKs phosphorylate c-JUN IEA Sus scrofa 456216 R-SSC-168140 https://reactome.org/PathwayBrowser/#/R-SSC-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Sus scrofa 456216 R-SSC-168162 https://reactome.org/PathwayBrowser/#/R-SSC-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Sus scrofa 456216 R-SSC-169905 https://reactome.org/PathwayBrowser/#/R-SSC-169905 ARMS is phosphorylated by active TrkA receptor IEA Sus scrofa 456216 R-SSC-170026 https://reactome.org/PathwayBrowser/#/R-SSC-170026 Protons are translocated from the intermembrane space to the matrix IEA Sus scrofa 456216 R-SSC-170055 https://reactome.org/PathwayBrowser/#/R-SSC-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Sus scrofa 456216 R-SSC-170070 https://reactome.org/PathwayBrowser/#/R-SSC-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Sus scrofa 456216 R-SSC-170076 https://reactome.org/PathwayBrowser/#/R-SSC-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Sus scrofa 456216 R-SSC-170087 https://reactome.org/PathwayBrowser/#/R-SSC-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Sus scrofa 456216 R-SSC-170126 https://reactome.org/PathwayBrowser/#/R-SSC-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Sus scrofa 456216 R-SSC-170843 https://reactome.org/PathwayBrowser/#/R-SSC-170843 TGFBR2 phosphorylates TGFBR1 IEA Sus scrofa 456216 R-SSC-170868 https://reactome.org/PathwayBrowser/#/R-SSC-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Sus scrofa 456216 R-SSC-170977 https://reactome.org/PathwayBrowser/#/R-SSC-170977 FRS2 is phosphorylated by active TrkA receptor IEA Sus scrofa 456216 R-SSC-174079 https://reactome.org/PathwayBrowser/#/R-SSC-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa 456216 R-SSC-174122 https://reactome.org/PathwayBrowser/#/R-SSC-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Sus scrofa 456216 R-SSC-174164 https://reactome.org/PathwayBrowser/#/R-SSC-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Sus scrofa 456216 R-SSC-174174 https://reactome.org/PathwayBrowser/#/R-SSC-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Sus scrofa 456216 R-SSC-174251 https://reactome.org/PathwayBrowser/#/R-SSC-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Sus scrofa 456216 R-SSC-174367 https://reactome.org/PathwayBrowser/#/R-SSC-174367 GCL ligates L-Glu to L-Cys IEA Sus scrofa 456216 R-SSC-174389 https://reactome.org/PathwayBrowser/#/R-SSC-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Sus scrofa 456216 R-SSC-174394 https://reactome.org/PathwayBrowser/#/R-SSC-174394 GSS:Mg2+ dimer synthesizes GSH IEA Sus scrofa 456216 R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa 456216 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa 456216 R-SSC-176116 https://reactome.org/PathwayBrowser/#/R-SSC-176116 Recruitment and activation of Chk1 IEA Sus scrofa 456216 R-SSC-176298 https://reactome.org/PathwayBrowser/#/R-SSC-176298 Activation of claspin IEA Sus scrofa 456216 R-SSC-177275 https://reactome.org/PathwayBrowser/#/R-SSC-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Sus scrofa 456216 R-SSC-177284 https://reactome.org/PathwayBrowser/#/R-SSC-177284 PKA phosphorylates PDE4B IEA Sus scrofa 456216 R-SSC-177930 https://reactome.org/PathwayBrowser/#/R-SSC-177930 GAB1 phosphorylation by EGFR kinase IEA Sus scrofa 456216 R-SSC-177933 https://reactome.org/PathwayBrowser/#/R-SSC-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Sus scrofa 456216 R-SSC-177934 https://reactome.org/PathwayBrowser/#/R-SSC-177934 EGFR autophosphorylation IEA Sus scrofa 456216 R-SSC-177937 https://reactome.org/PathwayBrowser/#/R-SSC-177937 Phosphorylation of EGFR by SRC kinase IEA Sus scrofa 456216 R-SSC-177939 https://reactome.org/PathwayBrowser/#/R-SSC-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Sus scrofa 456216 R-SSC-182969 https://reactome.org/PathwayBrowser/#/R-SSC-182969 Phosphorylation of CBL (EGFR:CBL) IEA Sus scrofa 456216 R-SSC-183058 https://reactome.org/PathwayBrowser/#/R-SSC-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Sus scrofa 456216 R-SSC-1855153 https://reactome.org/PathwayBrowser/#/R-SSC-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Sus scrofa 456216 R-SSC-1855157 https://reactome.org/PathwayBrowser/#/R-SSC-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Sus scrofa 456216 R-SSC-1855158 https://reactome.org/PathwayBrowser/#/R-SSC-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Sus scrofa 456216 R-SSC-1855162 https://reactome.org/PathwayBrowser/#/R-SSC-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Sus scrofa 456216 R-SSC-1855169 https://reactome.org/PathwayBrowser/#/R-SSC-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 456216 R-SSC-1855172 https://reactome.org/PathwayBrowser/#/R-SSC-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Sus scrofa 456216 R-SSC-1855176 https://reactome.org/PathwayBrowser/#/R-SSC-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Sus scrofa 456216 R-SSC-1855179 https://reactome.org/PathwayBrowser/#/R-SSC-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Sus scrofa 456216 R-SSC-1855181 https://reactome.org/PathwayBrowser/#/R-SSC-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Sus scrofa 456216 R-SSC-1855182 https://reactome.org/PathwayBrowser/#/R-SSC-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Sus scrofa 456216 R-SSC-1855193 https://reactome.org/PathwayBrowser/#/R-SSC-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Sus scrofa 456216 R-SSC-1855194 https://reactome.org/PathwayBrowser/#/R-SSC-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Sus scrofa 456216 R-SSC-1855197 https://reactome.org/PathwayBrowser/#/R-SSC-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 456216 R-SSC-1855207 https://reactome.org/PathwayBrowser/#/R-SSC-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Sus scrofa 456216 R-SSC-1855216 https://reactome.org/PathwayBrowser/#/R-SSC-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Sus scrofa 456216 R-SSC-1855223 https://reactome.org/PathwayBrowser/#/R-SSC-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Sus scrofa 456216 R-SSC-1855224 https://reactome.org/PathwayBrowser/#/R-SSC-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Sus scrofa 456216 R-SSC-1855227 https://reactome.org/PathwayBrowser/#/R-SSC-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Sus scrofa 456216 R-SSC-1855230 https://reactome.org/PathwayBrowser/#/R-SSC-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Sus scrofa 456216 R-SSC-1861595 https://reactome.org/PathwayBrowser/#/R-SSC-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Sus scrofa 456216 R-SSC-186786 https://reactome.org/PathwayBrowser/#/R-SSC-186786 Autophosphorylation of PDGF beta receptors IEA Sus scrofa 456216 R-SSC-186800 https://reactome.org/PathwayBrowser/#/R-SSC-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-187520 https://reactome.org/PathwayBrowser/#/R-SSC-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Sus scrofa 456216 R-SSC-187688 https://reactome.org/PathwayBrowser/#/R-SSC-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Sus scrofa 456216 R-SSC-187916 https://reactome.org/PathwayBrowser/#/R-SSC-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Sus scrofa 456216 R-SSC-187948 https://reactome.org/PathwayBrowser/#/R-SSC-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Sus scrofa 456216 R-SSC-187949 https://reactome.org/PathwayBrowser/#/R-SSC-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Sus scrofa 456216 R-SSC-187959 https://reactome.org/PathwayBrowser/#/R-SSC-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Sus scrofa 456216 R-SSC-188350 https://reactome.org/PathwayBrowser/#/R-SSC-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Sus scrofa 456216 R-SSC-188390 https://reactome.org/PathwayBrowser/#/R-SSC-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Sus scrofa 456216 R-SSC-190326 https://reactome.org/PathwayBrowser/#/R-SSC-190326 Autocatalytic phosphorylation of FGFR4 IEA Sus scrofa 456216 R-SSC-190427 https://reactome.org/PathwayBrowser/#/R-SSC-190427 Autocatalytic phosphorylation of FGFR1b IEA Sus scrofa 456216 R-SSC-190429 https://reactome.org/PathwayBrowser/#/R-SSC-190429 Autocatalytic phosphorylation of FGFR1c IEA Sus scrofa 456216 R-SSC-191062 https://reactome.org/PathwayBrowser/#/R-SSC-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Sus scrofa 456216 R-SSC-191380 https://reactome.org/PathwayBrowser/#/R-SSC-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Sus scrofa 456216 R-SSC-191414 https://reactome.org/PathwayBrowser/#/R-SSC-191414 MVD decarboxylates MVA5PP to IPPP IEA Sus scrofa 456216 R-SSC-191422 https://reactome.org/PathwayBrowser/#/R-SSC-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Sus scrofa 456216 R-SSC-191636 https://reactome.org/PathwayBrowser/#/R-SSC-191636 Phosphorylation of Cx43 by c-src IEA Sus scrofa 456216 R-SSC-193362 https://reactome.org/PathwayBrowser/#/R-SSC-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-193703 https://reactome.org/PathwayBrowser/#/R-SSC-193703 IKKbeta is activated IEA Sus scrofa 456216 R-SSC-193705 https://reactome.org/PathwayBrowser/#/R-SSC-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Sus scrofa 456216 R-SSC-194153 https://reactome.org/PathwayBrowser/#/R-SSC-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-195275 https://reactome.org/PathwayBrowser/#/R-SSC-195275 Phosphorylation of APC component of the destruction complex IEA Sus scrofa 456216 R-SSC-195283 https://reactome.org/PathwayBrowser/#/R-SSC-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Sus scrofa 456216 R-SSC-195287 https://reactome.org/PathwayBrowser/#/R-SSC-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Sus scrofa 456216 R-SSC-195300 https://reactome.org/PathwayBrowser/#/R-SSC-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Sus scrofa 456216 R-SSC-195318 https://reactome.org/PathwayBrowser/#/R-SSC-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Sus scrofa 456216 R-SSC-1963581 https://reactome.org/PathwayBrowser/#/R-SSC-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Sus scrofa 456216 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 456216 R-SSC-1963586 https://reactome.org/PathwayBrowser/#/R-SSC-1963586 SRC family kinases phosphorylate ERBB2 IEA Sus scrofa 456216 R-SSC-196773 https://reactome.org/PathwayBrowser/#/R-SSC-196773 COASY phosphorylates DP-CoA IEA Sus scrofa 456216 R-SSC-196857 https://reactome.org/PathwayBrowser/#/R-SSC-196857 PANK2 phosphorylates PanK IEA Sus scrofa 456216 R-SSC-196964 https://reactome.org/PathwayBrowser/#/R-SSC-196964 RFK:Mg2+ phosphorylates RIB IEA Sus scrofa 456216 R-SSC-197198 https://reactome.org/PathwayBrowser/#/R-SSC-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Sus scrofa 456216 R-SSC-197958 https://reactome.org/PathwayBrowser/#/R-SSC-197958 FPGS-2 transforms THF to THFPG IEA Sus scrofa 456216 R-SSC-198266 https://reactome.org/PathwayBrowser/#/R-SSC-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Sus scrofa 456216 R-SSC-198314 https://reactome.org/PathwayBrowser/#/R-SSC-198314 DAG stimulates protein kinase C-delta IEA Sus scrofa 456216 R-SSC-198669 https://reactome.org/PathwayBrowser/#/R-SSC-198669 p38MAPK phosphorylates MSK1 IEA Sus scrofa 456216 R-SSC-198746 https://reactome.org/PathwayBrowser/#/R-SSC-198746 ERK1/2/5 activate RSK1/2/3 IEA Sus scrofa 456216 R-SSC-198756 https://reactome.org/PathwayBrowser/#/R-SSC-198756 ERK1/2 phosphorylates MSK1 IEA Sus scrofa 456216 R-SSC-199203 https://reactome.org/PathwayBrowser/#/R-SSC-199203 PANK1/3 phosphorylate PanK IEA Sus scrofa 456216 R-SSC-199895 https://reactome.org/PathwayBrowser/#/R-SSC-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Sus scrofa 456216 R-SSC-199910 https://reactome.org/PathwayBrowser/#/R-SSC-199910 MSK1 activates ATF1 IEA Sus scrofa 456216 R-SSC-199917 https://reactome.org/PathwayBrowser/#/R-SSC-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Sus scrofa 456216 R-SSC-199935 https://reactome.org/PathwayBrowser/#/R-SSC-199935 MSK1 activates CREB IEA Sus scrofa 456216 R-SSC-200318 https://reactome.org/PathwayBrowser/#/R-SSC-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Sus scrofa 456216 R-SSC-200326 https://reactome.org/PathwayBrowser/#/R-SSC-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Sus scrofa 456216 R-SSC-200421 https://reactome.org/PathwayBrowser/#/R-SSC-200421 Activation of cytosolic AMPK by phosphorylation IEA Sus scrofa 456216 R-SSC-200423 https://reactome.org/PathwayBrowser/#/R-SSC-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Sus scrofa 456216 R-SSC-200555 https://reactome.org/PathwayBrowser/#/R-SSC-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Sus scrofa 456216 R-SSC-200681 https://reactome.org/PathwayBrowser/#/R-SSC-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Sus scrofa 456216 R-SSC-200682 https://reactome.org/PathwayBrowser/#/R-SSC-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Sus scrofa 456216 R-SSC-200711 https://reactome.org/PathwayBrowser/#/R-SSC-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Sus scrofa 456216 R-SSC-201443 https://reactome.org/PathwayBrowser/#/R-SSC-201443 Type II receptor phosphorylates type I receptor IEA Sus scrofa 456216 R-SSC-201476 https://reactome.org/PathwayBrowser/#/R-SSC-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Sus scrofa 456216 R-SSC-201510 https://reactome.org/PathwayBrowser/#/R-SSC-201510 PI3K synthesizes PIP3 downstream of ALK IEA Sus scrofa 456216 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 456216 R-SSC-201677 https://reactome.org/PathwayBrowser/#/R-SSC-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Sus scrofa 456216 R-SSC-201717 https://reactome.org/PathwayBrowser/#/R-SSC-201717 CSNK2-mediated phosphorylation of DVL IEA Sus scrofa 456216 R-SSC-202111 https://reactome.org/PathwayBrowser/#/R-SSC-202111 AKT1 phosphorylates eNOS IEA Sus scrofa 456216 R-SSC-202165 https://reactome.org/PathwayBrowser/#/R-SSC-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Sus scrofa 456216 R-SSC-202168 https://reactome.org/PathwayBrowser/#/R-SSC-202168 Phosphorylation of ZAP-70 by Lck IEA Sus scrofa 456216 R-SSC-202174 https://reactome.org/PathwayBrowser/#/R-SSC-202174 Activation of ZAP-70 IEA Sus scrofa 456216 R-SSC-202216 https://reactome.org/PathwayBrowser/#/R-SSC-202216 Phosphorylation of SLP-76 IEA Sus scrofa 456216 R-SSC-202222 https://reactome.org/PathwayBrowser/#/R-SSC-202222 Phosphorylation of PKC theta IEA Sus scrofa 456216 R-SSC-202233 https://reactome.org/PathwayBrowser/#/R-SSC-202233 Inactivation of Lck by Csk IEA Sus scrofa 456216 R-SSC-202245 https://reactome.org/PathwayBrowser/#/R-SSC-202245 Phosphorylation of TBSMs in LAT IEA Sus scrofa 456216 R-SSC-202248 https://reactome.org/PathwayBrowser/#/R-SSC-202248 Phosphorylation of PLC-gamma1 IEA Sus scrofa 456216 R-SSC-202291 https://reactome.org/PathwayBrowser/#/R-SSC-202291 Activation of Lck IEA Sus scrofa 456216 R-SSC-202307 https://reactome.org/PathwayBrowser/#/R-SSC-202307 Change of PKC theta conformation IEA Sus scrofa 456216 R-SSC-202365 https://reactome.org/PathwayBrowser/#/R-SSC-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-202437 https://reactome.org/PathwayBrowser/#/R-SSC-202437 Phosphorylation of CARMA1 IEA Sus scrofa 456216 R-SSC-202459 https://reactome.org/PathwayBrowser/#/R-SSC-202459 Phosphorylation of Bcl10 IEA Sus scrofa 456216 R-SSC-202500 https://reactome.org/PathwayBrowser/#/R-SSC-202500 Activation of IKK complex IEA Sus scrofa 456216 R-SSC-202510 https://reactome.org/PathwayBrowser/#/R-SSC-202510 Activation of TAK1-TAB2 complex IEA Sus scrofa 456216 R-SSC-202541 https://reactome.org/PathwayBrowser/#/R-SSC-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Sus scrofa 456216 R-SSC-2028284 https://reactome.org/PathwayBrowser/#/R-SSC-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Sus scrofa 456216 R-SSC-2028555 https://reactome.org/PathwayBrowser/#/R-SSC-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Sus scrofa 456216 R-SSC-2028583 https://reactome.org/PathwayBrowser/#/R-SSC-2028583 Phosphorylation of YAP by LATS2 IEA Sus scrofa 456216 R-SSC-2028589 https://reactome.org/PathwayBrowser/#/R-SSC-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Sus scrofa 456216 R-SSC-2028591 https://reactome.org/PathwayBrowser/#/R-SSC-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Sus scrofa 456216 R-SSC-2028598 https://reactome.org/PathwayBrowser/#/R-SSC-2028598 Phosphorylation of YAP by LATS1 IEA Sus scrofa 456216 R-SSC-2028629 https://reactome.org/PathwayBrowser/#/R-SSC-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Sus scrofa 456216 R-SSC-2028635 https://reactome.org/PathwayBrowser/#/R-SSC-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Sus scrofa 456216 R-SSC-2028661 https://reactome.org/PathwayBrowser/#/R-SSC-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Sus scrofa 456216 R-SSC-2028670 https://reactome.org/PathwayBrowser/#/R-SSC-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Sus scrofa 456216 R-SSC-2028673 https://reactome.org/PathwayBrowser/#/R-SSC-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Sus scrofa 456216 R-SSC-2028675 https://reactome.org/PathwayBrowser/#/R-SSC-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Sus scrofa 456216 R-SSC-2028679 https://reactome.org/PathwayBrowser/#/R-SSC-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Sus scrofa 456216 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa 456216 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa 456216 R-SSC-2029454 https://reactome.org/PathwayBrowser/#/R-SSC-2029454 Autophosphorylation of PAK1 IEA Sus scrofa 456216 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa 456216 R-SSC-2029460 https://reactome.org/PathwayBrowser/#/R-SSC-2029460 PAK1 phosphorylates LIMK1 IEA Sus scrofa 456216 R-SSC-2029469 https://reactome.org/PathwayBrowser/#/R-SSC-2029469 p-ERK phosphorylates WAVEs and ABI IEA Sus scrofa 456216 R-SSC-2029473 https://reactome.org/PathwayBrowser/#/R-SSC-2029473 Branching and elongation of mother and daughter filaments IEA Sus scrofa 456216 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa 456216 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 456216 R-SSC-2046087 https://reactome.org/PathwayBrowser/#/R-SSC-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Sus scrofa 456216 R-SSC-2046093 https://reactome.org/PathwayBrowser/#/R-SSC-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Sus scrofa 456216 R-SSC-205075 https://reactome.org/PathwayBrowser/#/R-SSC-205075 JNK phosphorylates BIM, BAD and other targets IEA Sus scrofa 456216 R-SSC-205136 https://reactome.org/PathwayBrowser/#/R-SSC-205136 GTP-bound RAC contributes to JNK activation IEA Sus scrofa 456216 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 456216 R-SSC-2060328 https://reactome.org/PathwayBrowser/#/R-SSC-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Sus scrofa 456216 R-SSC-209087 https://reactome.org/PathwayBrowser/#/R-SSC-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Sus scrofa 456216 R-SSC-210291 https://reactome.org/PathwayBrowser/#/R-SSC-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Sus scrofa 456216 R-SSC-212710 https://reactome.org/PathwayBrowser/#/R-SSC-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Sus scrofa 456216 R-SSC-2130194 https://reactome.org/PathwayBrowser/#/R-SSC-2130194 ABL phosphorylates WAVEs IEA Sus scrofa 456216 R-SSC-2162073 https://reactome.org/PathwayBrowser/#/R-SSC-2162073 carbovir monophosphate + ATP => carbovir diphosphate + ADP TAS Sus scrofa 456216 R-SSC-216723 https://reactome.org/PathwayBrowser/#/R-SSC-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Sus scrofa 456216 R-SSC-216757 https://reactome.org/PathwayBrowser/#/R-SSC-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Sus scrofa 456216 R-SSC-2168079 https://reactome.org/PathwayBrowser/#/R-SSC-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Sus scrofa 456216 R-SSC-2176475 https://reactome.org/PathwayBrowser/#/R-SSC-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Sus scrofa 456216 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa 456216 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa 456216 R-SSC-2214351 https://reactome.org/PathwayBrowser/#/R-SSC-2214351 PLK1 phosphorylates GORASP1 IEA Sus scrofa 456216 R-SSC-2267372 https://reactome.org/PathwayBrowser/#/R-SSC-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Sus scrofa 456216 R-SSC-2294580 https://reactome.org/PathwayBrowser/#/R-SSC-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Sus scrofa 456216 R-SSC-2294600 https://reactome.org/PathwayBrowser/#/R-SSC-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Sus scrofa 456216 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-2395412 https://reactome.org/PathwayBrowser/#/R-SSC-2395412 Phosphorylation of SYK IEA Sus scrofa 456216 R-SSC-2395801 https://reactome.org/PathwayBrowser/#/R-SSC-2395801 Phosphorylation of LAT by p-SYK IEA Sus scrofa 456216 R-SSC-2396002 https://reactome.org/PathwayBrowser/#/R-SSC-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex IEA Sus scrofa 456216 R-SSC-2396007 https://reactome.org/PathwayBrowser/#/R-SSC-2396007 IRF3 is phosphorylated by TBK1 IEA Sus scrofa 456216 R-SSC-2396594 https://reactome.org/PathwayBrowser/#/R-SSC-2396594 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa 456216 R-SSC-2404193 https://reactome.org/PathwayBrowser/#/R-SSC-2404193 IGF1R phosphorylates SHC1 IEA Sus scrofa 456216 R-SSC-2404199 https://reactome.org/PathwayBrowser/#/R-SSC-2404199 IGF1,2:IGF1R autophosphorylates IEA Sus scrofa 456216 R-SSC-2422927 https://reactome.org/PathwayBrowser/#/R-SSC-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Sus scrofa 456216 R-SSC-2424480 https://reactome.org/PathwayBrowser/#/R-SSC-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-2424484 https://reactome.org/PathwayBrowser/#/R-SSC-2424484 Phosphorylation of BTK by p-SYK IEA Sus scrofa 456216 R-SSC-2424486 https://reactome.org/PathwayBrowser/#/R-SSC-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Sus scrofa 456216 R-SSC-2424487 https://reactome.org/PathwayBrowser/#/R-SSC-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Sus scrofa 456216 R-SSC-2428926 https://reactome.org/PathwayBrowser/#/R-SSC-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Sus scrofa 456216 R-SSC-2430535 https://reactome.org/PathwayBrowser/#/R-SSC-2430535 MASTL phosphorylates ENSA IEA Sus scrofa 456216 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa 456216 R-SSC-2466068 https://reactome.org/PathwayBrowser/#/R-SSC-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Sus scrofa 456216 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa 456216 R-SSC-2468293 https://reactome.org/PathwayBrowser/#/R-SSC-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Sus scrofa 456216 R-SSC-2529020 https://reactome.org/PathwayBrowser/#/R-SSC-2529020 CK2 phosphorylates condensin I subunits IEA Sus scrofa 456216 R-SSC-2562526 https://reactome.org/PathwayBrowser/#/R-SSC-2562526 PLK1 phosphorylates OPTN IEA Sus scrofa 456216 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa 456216 R-SSC-2581474 https://reactome.org/PathwayBrowser/#/R-SSC-2581474 GRK1,4,7 phosphorylate MII to p-MII IEA Sus scrofa 456216 R-SSC-265682 https://reactome.org/PathwayBrowser/#/R-SSC-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Sus scrofa 456216 R-SSC-265783 https://reactome.org/PathwayBrowser/#/R-SSC-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-266082 https://reactome.org/PathwayBrowser/#/R-SSC-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Sus scrofa 456216 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa 456216 R-SSC-2730835 https://reactome.org/PathwayBrowser/#/R-SSC-2730835 Autophosphorylation of PKC-theta IEA Sus scrofa 456216 R-SSC-2730841 https://reactome.org/PathwayBrowser/#/R-SSC-2730841 Phosphorylation and activation of VAV IEA Sus scrofa 456216 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa 456216 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa 456216 R-SSC-2730856 https://reactome.org/PathwayBrowser/#/R-SSC-2730856 Autophosphorylation of PAK IEA Sus scrofa 456216 R-SSC-2730858 https://reactome.org/PathwayBrowser/#/R-SSC-2730858 Autophosphorylation of BTK/ITK IEA Sus scrofa 456216 R-SSC-2730862 https://reactome.org/PathwayBrowser/#/R-SSC-2730862 Autophosphorylation of LYN kinase IEA Sus scrofa 456216 R-SSC-2730863 https://reactome.org/PathwayBrowser/#/R-SSC-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Sus scrofa 456216 R-SSC-2730870 https://reactome.org/PathwayBrowser/#/R-SSC-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Sus scrofa 456216 R-SSC-2730876 https://reactome.org/PathwayBrowser/#/R-SSC-2730876 Phosphorylation of IKK-beta by TAK1 IEA Sus scrofa 456216 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa 456216 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa 456216 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa 456216 R-SSC-2730896 https://reactome.org/PathwayBrowser/#/R-SSC-2730896 Phosphorylation of MEK4 by MEKK1 IEA Sus scrofa 456216 R-SSC-2730900 https://reactome.org/PathwayBrowser/#/R-SSC-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Sus scrofa 456216 R-SSC-2984220 https://reactome.org/PathwayBrowser/#/R-SSC-2984220 CDK1:CCNB phosphorylates NEK9 IEA Sus scrofa 456216 R-SSC-2984226 https://reactome.org/PathwayBrowser/#/R-SSC-2984226 PLK1 phosphorylates NEK9 IEA Sus scrofa 456216 R-SSC-2984258 https://reactome.org/PathwayBrowser/#/R-SSC-2984258 NEK9 phosphorylates NEK6/NEK7 IEA Sus scrofa 456216 R-SSC-2990880 https://reactome.org/PathwayBrowser/#/R-SSC-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Sus scrofa 456216 R-SSC-2990882 https://reactome.org/PathwayBrowser/#/R-SSC-2990882 CDK1 phosphorylates NUP98 IEA Sus scrofa 456216 R-SSC-2993898 https://reactome.org/PathwayBrowser/#/R-SSC-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Sus scrofa 456216 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa 456216 R-SSC-3000327 https://reactome.org/PathwayBrowser/#/R-SSC-3000327 PLK1 phosphorylates BORA IEA Sus scrofa 456216 R-SSC-3095901 https://reactome.org/PathwayBrowser/#/R-SSC-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Sus scrofa 456216 R-SSC-3132737 https://reactome.org/PathwayBrowser/#/R-SSC-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Sus scrofa 456216 R-SSC-3222006 https://reactome.org/PathwayBrowser/#/R-SSC-3222006 STK11 (LKB1) phosphorylates NUAK1 IEA Sus scrofa 456216 R-SSC-3222020 https://reactome.org/PathwayBrowser/#/R-SSC-3222020 NUAK1 phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-3228469 https://reactome.org/PathwayBrowser/#/R-SSC-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Sus scrofa 456216 R-SSC-3229102 https://reactome.org/PathwayBrowser/#/R-SSC-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Sus scrofa 456216 R-SSC-3238999 https://reactome.org/PathwayBrowser/#/R-SSC-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Sus scrofa 456216 R-SSC-3239014 https://reactome.org/PathwayBrowser/#/R-SSC-3239014 MAPKAPK5 phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-3239019 https://reactome.org/PathwayBrowser/#/R-SSC-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Sus scrofa 456216 R-SSC-3249371 https://reactome.org/PathwayBrowser/#/R-SSC-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Sus scrofa 456216 R-SSC-3249379 https://reactome.org/PathwayBrowser/#/R-SSC-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Sus scrofa 456216 R-SSC-3249390 https://reactome.org/PathwayBrowser/#/R-SSC-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Sus scrofa 456216 R-SSC-3371422 https://reactome.org/PathwayBrowser/#/R-SSC-3371422 ATP hydrolysis by HSP70 IEA Sus scrofa 456216 R-SSC-3371435 https://reactome.org/PathwayBrowser/#/R-SSC-3371435 Constitutive phosphorylation by GSK3 IEA Sus scrofa 456216 R-SSC-3371503 https://reactome.org/PathwayBrowser/#/R-SSC-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Sus scrofa 456216 R-SSC-3371531 https://reactome.org/PathwayBrowser/#/R-SSC-3371531 Constitutive phosphorylation by pERK1/2 IEA Sus scrofa 456216 R-SSC-349444 https://reactome.org/PathwayBrowser/#/R-SSC-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Sus scrofa 456216 R-SSC-354073 https://reactome.org/PathwayBrowser/#/R-SSC-354073 Autophosphorylation of PTK2 at Y397 IEA Sus scrofa 456216 R-SSC-354124 https://reactome.org/PathwayBrowser/#/R-SSC-354124 Phosphorylation of pPTK2 by SRC IEA Sus scrofa 456216 R-SSC-372693 https://reactome.org/PathwayBrowser/#/R-SSC-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Sus scrofa 456216 R-SSC-373747 https://reactome.org/PathwayBrowser/#/R-SSC-373747 Phosphorylation of nephrin by FYN IEA Sus scrofa 456216 R-SSC-373750 https://reactome.org/PathwayBrowser/#/R-SSC-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Sus scrofa 456216 R-SSC-374664 https://reactome.org/PathwayBrowser/#/R-SSC-374664 Phosphorylation and activation of Ezrin IEA Sus scrofa 456216 R-SSC-3772435 https://reactome.org/PathwayBrowser/#/R-SSC-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Sus scrofa 456216 R-SSC-3772436 https://reactome.org/PathwayBrowser/#/R-SSC-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Sus scrofa 456216 R-SSC-377640 https://reactome.org/PathwayBrowser/#/R-SSC-377640 Autophosphorylation of SRC IEA Sus scrofa 456216 R-SSC-3788705 https://reactome.org/PathwayBrowser/#/R-SSC-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa 456216 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 456216 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 456216 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa 456216 R-SSC-380278 https://reactome.org/PathwayBrowser/#/R-SSC-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Sus scrofa 456216 R-SSC-380780 https://reactome.org/PathwayBrowser/#/R-SSC-380780 Activation of Src IEA Sus scrofa 456216 R-SSC-380927 https://reactome.org/PathwayBrowser/#/R-SSC-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Sus scrofa 456216 R-SSC-381111 https://reactome.org/PathwayBrowser/#/R-SSC-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Sus scrofa 456216 R-SSC-382553 https://reactome.org/PathwayBrowser/#/R-SSC-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Sus scrofa 456216 R-SSC-382560 https://reactome.org/PathwayBrowser/#/R-SSC-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Sus scrofa 456216 R-SSC-382575 https://reactome.org/PathwayBrowser/#/R-SSC-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Sus scrofa 456216 R-SSC-383190 https://reactome.org/PathwayBrowser/#/R-SSC-383190 HCO3- transport through ion channel IEA Sus scrofa 456216 R-SSC-3857329 https://reactome.org/PathwayBrowser/#/R-SSC-3857329 MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB IEA Sus scrofa 456216 R-SSC-388831 https://reactome.org/PathwayBrowser/#/R-SSC-388831 Phosphorylation of CD28 IEA Sus scrofa 456216 R-SSC-388833 https://reactome.org/PathwayBrowser/#/R-SSC-388833 Phosphorylation of CTLA-4 IEA Sus scrofa 456216 R-SSC-389083 https://reactome.org/PathwayBrowser/#/R-SSC-389083 Autophosphorylation of PDGF alpha receptors IEA Sus scrofa 456216 R-SSC-389086 https://reactome.org/PathwayBrowser/#/R-SSC-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Sus scrofa 456216 R-SSC-389158 https://reactome.org/PathwayBrowser/#/R-SSC-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-389354 https://reactome.org/PathwayBrowser/#/R-SSC-389354 Activation of Vav1 IEA Sus scrofa 456216 R-SSC-389762 https://reactome.org/PathwayBrowser/#/R-SSC-389762 Phosphorylation of PD-1 IEA Sus scrofa 456216 R-SSC-390593 https://reactome.org/PathwayBrowser/#/R-SSC-390593 ATP Hydrolysis By Myosin IEA Sus scrofa 456216 R-SSC-390597 https://reactome.org/PathwayBrowser/#/R-SSC-390597 Release Of ADP From Myosin IEA Sus scrofa 456216 R-SSC-391266 https://reactome.org/PathwayBrowser/#/R-SSC-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Sus scrofa 456216 R-SSC-392187 https://reactome.org/PathwayBrowser/#/R-SSC-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Sus scrofa 456216 R-SSC-392195 https://reactome.org/PathwayBrowser/#/R-SSC-392195 Gi activation by P2Y purinoceptor 12 IEA Sus scrofa 456216 R-SSC-392202 https://reactome.org/PathwayBrowser/#/R-SSC-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Sus scrofa 456216 R-SSC-392300 https://reactome.org/PathwayBrowser/#/R-SSC-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-392530 https://reactome.org/PathwayBrowser/#/R-SSC-392530 p-S400-Cot phosphorylates NIK IEA Sus scrofa 456216 R-SSC-3928578 https://reactome.org/PathwayBrowser/#/R-SSC-3928578 EPH receptors autophosphorylate IEA Sus scrofa 456216 R-SSC-3928604 https://reactome.org/PathwayBrowser/#/R-SSC-3928604 SFKs phosphorylate VAV2,3 IEA Sus scrofa 456216 R-SSC-3928620 https://reactome.org/PathwayBrowser/#/R-SSC-3928620 PAK1 autophosphorylates IEA Sus scrofa 456216 R-SSC-3928625 https://reactome.org/PathwayBrowser/#/R-SSC-3928625 PAKs autophosphorylate IEA Sus scrofa 456216 R-SSC-3928627 https://reactome.org/PathwayBrowser/#/R-SSC-3928627 EPHB phosphorylates TIAM1 IEA Sus scrofa 456216 R-SSC-3928640 https://reactome.org/PathwayBrowser/#/R-SSC-3928640 PAKs phosphorylate MLC IEA Sus scrofa 456216 R-SSC-399939 https://reactome.org/PathwayBrowser/#/R-SSC-399939 Autophosphorylation of PAK IEA Sus scrofa 456216 R-SSC-399944 https://reactome.org/PathwayBrowser/#/R-SSC-399944 Phosphorylation of CRMPs by Cdk5 IEA Sus scrofa 456216 R-SSC-399947 https://reactome.org/PathwayBrowser/#/R-SSC-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Sus scrofa 456216 R-SSC-399951 https://reactome.org/PathwayBrowser/#/R-SSC-399951 Phosphorylation of CRMPs by GSK3beta IEA Sus scrofa 456216 R-SSC-399952 https://reactome.org/PathwayBrowser/#/R-SSC-399952 Phosphorylation of LIMK-1 by PAK IEA Sus scrofa 456216 R-SSC-399978 https://reactome.org/PathwayBrowser/#/R-SSC-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Sus scrofa 456216 R-SSC-4085028 https://reactome.org/PathwayBrowser/#/R-SSC-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Sus scrofa 456216 R-SSC-4086410 https://reactome.org/PathwayBrowser/#/R-SSC-4086410 CDK1 phosphorylates BORA IEA Sus scrofa 456216 R-SSC-4088024 https://reactome.org/PathwayBrowser/#/R-SSC-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Sus scrofa 456216 R-SSC-4088134 https://reactome.org/PathwayBrowser/#/R-SSC-4088134 PLK1 phosphorylates FOXM1 IEA Sus scrofa 456216 R-SSC-4093332 https://reactome.org/PathwayBrowser/#/R-SSC-4093332 p-EPHB phosphorylates SDC2 IEA Sus scrofa 456216 R-SSC-416320 https://reactome.org/PathwayBrowser/#/R-SSC-416320 Trafficking of GluR1-containing AMPA receptors IEA Sus scrofa 456216 R-SSC-416639 https://reactome.org/PathwayBrowser/#/R-SSC-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Sus scrofa 456216 R-SSC-416985 https://reactome.org/PathwayBrowser/#/R-SSC-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Sus scrofa 456216 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa 456216 R-SSC-417843 https://reactome.org/PathwayBrowser/#/R-SSC-417843 P2Y13 binds ADP IEA Sus scrofa 456216 R-SSC-417908 https://reactome.org/PathwayBrowser/#/R-SSC-417908 P2RY1 binds ADP IEA Sus scrofa 456216 R-SSC-418576 https://reactome.org/PathwayBrowser/#/R-SSC-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Sus scrofa 456216 R-SSC-418845 https://reactome.org/PathwayBrowser/#/R-SSC-418845 Activation of caspase-3 IEA Sus scrofa 456216 R-SSC-419644 https://reactome.org/PathwayBrowser/#/R-SSC-419644 Transphosphorylation of pLIMK1 IEA Sus scrofa 456216 R-SSC-419646 https://reactome.org/PathwayBrowser/#/R-SSC-419646 SEMA4D interacts with Plexin-B1:Met IEA Sus scrofa 456216 R-SSC-421007 https://reactome.org/PathwayBrowser/#/R-SSC-421007 Endocytosis of Ca impermeable AMPA receptors IEA Sus scrofa 456216 R-SSC-426240 https://reactome.org/PathwayBrowser/#/R-SSC-426240 DAG kinase produces phosphatidic acid from DAG IEA Sus scrofa 456216 R-SSC-428273 https://reactome.org/PathwayBrowser/#/R-SSC-428273 SPHK1 phosphorylates sphingoid IEA Sus scrofa 456216 R-SSC-428941 https://reactome.org/PathwayBrowser/#/R-SSC-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Sus scrofa 456216 R-SSC-428961 https://reactome.org/PathwayBrowser/#/R-SSC-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Sus scrofa 456216 R-SSC-429016 https://reactome.org/PathwayBrowser/#/R-SSC-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Sus scrofa 456216 R-SSC-429157 https://reactome.org/PathwayBrowser/#/R-SSC-429157 ABCC4 accumulation of dense granule contents IEA Sus scrofa 456216 R-SSC-429441 https://reactome.org/PathwayBrowser/#/R-SSC-429441 SYK activation by SRC IEA Sus scrofa 456216 R-SSC-429449 https://reactome.org/PathwayBrowser/#/R-SSC-429449 Syk activation leads to SLP-76 activation IEA Sus scrofa 456216 R-SSC-432129 https://reactome.org/PathwayBrowser/#/R-SSC-432129 FGR binds and phosphorylates LRP8 IEA Sus scrofa 456216 R-SSC-432148 https://reactome.org/PathwayBrowser/#/R-SSC-432148 Fgr may phosphorylate p38 MAPK IEA Sus scrofa 456216 R-SSC-432232 https://reactome.org/PathwayBrowser/#/R-SSC-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Sus scrofa 456216 R-SSC-4332358 https://reactome.org/PathwayBrowser/#/R-SSC-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Sus scrofa 456216 R-SSC-4332363 https://reactome.org/PathwayBrowser/#/R-SSC-4332363 Autophosphorylation and activation of CAMK2 IEA Sus scrofa 456216 R-SSC-434836 https://reactome.org/PathwayBrowser/#/R-SSC-434836 Syk/Lck phosphorylate LAT IEA Sus scrofa 456216 R-SSC-435244 https://reactome.org/PathwayBrowser/#/R-SSC-435244 PECAM1 is phosphorylated IEA Sus scrofa 456216 R-SSC-437162 https://reactome.org/PathwayBrowser/#/R-SSC-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-4411383 https://reactome.org/PathwayBrowser/#/R-SSC-4411383 NLK phosphorylates TCF/LEF IEA Sus scrofa 456216 R-SSC-4411402 https://reactome.org/PathwayBrowser/#/R-SSC-4411402 Activation of NLK IEA Sus scrofa 456216 R-SSC-4420117 https://reactome.org/PathwayBrowser/#/R-SSC-4420117 VEGFR2 autophosphorylates IEA Sus scrofa 456216 R-SSC-4420121 https://reactome.org/PathwayBrowser/#/R-SSC-4420121 SFKs phosphorylate PLCG1 IEA Sus scrofa 456216 R-SSC-4420128 https://reactome.org/PathwayBrowser/#/R-SSC-4420128 SRC-1 phosphorylates SHB IEA Sus scrofa 456216 R-SSC-4420206 https://reactome.org/PathwayBrowser/#/R-SSC-4420206 Phosphorylation of SRC-1 IEA Sus scrofa 456216 R-SSC-442724 https://reactome.org/PathwayBrowser/#/R-SSC-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Sus scrofa 456216 R-SSC-442749 https://reactome.org/PathwayBrowser/#/R-SSC-442749 CaMKK autophosphorylates in the nucleus IEA Sus scrofa 456216 R-SSC-445072 https://reactome.org/PathwayBrowser/#/R-SSC-445072 Interaction of PAK1 with Rac1-GTP IEA Sus scrofa 456216 R-SSC-445079 https://reactome.org/PathwayBrowser/#/R-SSC-445079 Phosphorylation of L1 by ERK IEA Sus scrofa 456216 R-SSC-445699 https://reactome.org/PathwayBrowser/#/R-SSC-445699 ATP Hydrolysis By Myosin IEA Sus scrofa 456216 R-SSC-445705 https://reactome.org/PathwayBrowser/#/R-SSC-445705 Release Of ADP From Myosin IEA Sus scrofa 456216 R-SSC-445813 https://reactome.org/PathwayBrowser/#/R-SSC-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Sus scrofa 456216 R-SSC-446634 https://reactome.org/PathwayBrowser/#/R-SSC-446634 IRAK4 is activated by autophosphorylation IEA Sus scrofa 456216 R-SSC-446694 https://reactome.org/PathwayBrowser/#/R-SSC-446694 IRAK4 phosphorylates IRAK1 IEA Sus scrofa 456216 R-SSC-446701 https://reactome.org/PathwayBrowser/#/R-SSC-446701 IRAK4-activated IRAK1 autophosphorylates IEA Sus scrofa 456216 R-SSC-447074 https://reactome.org/PathwayBrowser/#/R-SSC-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Sus scrofa 456216 R-SSC-448955 https://reactome.org/PathwayBrowser/#/R-SSC-448955 Phosphorylation of MEF2 proteins by p38 IEA Sus scrofa 456216 R-SSC-450222 https://reactome.org/PathwayBrowser/#/R-SSC-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Sus scrofa 456216 R-SSC-450325 https://reactome.org/PathwayBrowser/#/R-SSC-450325 c-FOS activation by phospho ERK1/2 IEA Sus scrofa 456216 R-SSC-450333 https://reactome.org/PathwayBrowser/#/R-SSC-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Sus scrofa 456216 R-SSC-450337 https://reactome.org/PathwayBrowser/#/R-SSC-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Sus scrofa 456216 R-SSC-450346 https://reactome.org/PathwayBrowser/#/R-SSC-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Sus scrofa 456216 R-SSC-450463 https://reactome.org/PathwayBrowser/#/R-SSC-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Sus scrofa 456216 R-SSC-450474 https://reactome.org/PathwayBrowser/#/R-SSC-450474 MK2 phosphorylates BRF1 IEA Sus scrofa 456216 R-SSC-450533 https://reactome.org/PathwayBrowser/#/R-SSC-450533 PKCdelta phosphorylates HuR IEA Sus scrofa 456216 R-SSC-450550 https://reactome.org/PathwayBrowser/#/R-SSC-450550 PKCalpha phosphorylates HuR IEA Sus scrofa 456216 R-SSC-450827 https://reactome.org/PathwayBrowser/#/R-SSC-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. IEA Sus scrofa 456216 R-SSC-451942 https://reactome.org/PathwayBrowser/#/R-SSC-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Sus scrofa 456216 R-SSC-452097 https://reactome.org/PathwayBrowser/#/R-SSC-452097 Recruited STAT5 is phosphorylated IEA Sus scrofa 456216 R-SSC-452100 https://reactome.org/PathwayBrowser/#/R-SSC-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Sus scrofa 456216 R-SSC-452122 https://reactome.org/PathwayBrowser/#/R-SSC-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Sus scrofa 456216 R-SSC-453200 https://reactome.org/PathwayBrowser/#/R-SSC-453200 SYK autophosphorylates IEA Sus scrofa 456216 R-SSC-4793911 https://reactome.org/PathwayBrowser/#/R-SSC-4793911 MAPKAPK2 phosphorylates HSF1 IEA Sus scrofa 456216 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 456216 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 456216 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 456216 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 456216 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 456216 R-SSC-504054 https://reactome.org/PathwayBrowser/#/R-SSC-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Sus scrofa 456216 R-SSC-508040 https://reactome.org/PathwayBrowser/#/R-SSC-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Sus scrofa 456216 R-SSC-5082387 https://reactome.org/PathwayBrowser/#/R-SSC-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Sus scrofa 456216 R-SSC-5082405 https://reactome.org/PathwayBrowser/#/R-SSC-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Sus scrofa 456216 R-SSC-508282 https://reactome.org/PathwayBrowser/#/R-SSC-508282 SYK is a substrate for JAK1 IEA Sus scrofa 456216 R-SSC-508308 https://reactome.org/PathwayBrowser/#/R-SSC-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Sus scrofa 456216 R-SSC-5138432 https://reactome.org/PathwayBrowser/#/R-SSC-5138432 DVL2 is phosphorylated by PKC IEA Sus scrofa 456216 R-SSC-5195402 https://reactome.org/PathwayBrowser/#/R-SSC-5195402 CDK1 phosphorylates LPIN IEA Sus scrofa 456216 R-SSC-5213464 https://reactome.org/PathwayBrowser/#/R-SSC-5213464 RIPK1 is phosphorylated IEA Sus scrofa 456216 R-SSC-5213466 https://reactome.org/PathwayBrowser/#/R-SSC-5213466 RIPK3 is phosphorylated IEA Sus scrofa 456216 R-SSC-5218640 https://reactome.org/PathwayBrowser/#/R-SSC-5218640 SRC-1 phosphorylates p-Y397-PTK2 IEA Sus scrofa 456216 R-SSC-5218642 https://reactome.org/PathwayBrowser/#/R-SSC-5218642 PTK2 autophosphorylates IEA Sus scrofa 456216 R-SSC-5218804 https://reactome.org/PathwayBrowser/#/R-SSC-5218804 p38 MAPK activation by VEGFR IEA Sus scrofa 456216 R-SSC-5218805 https://reactome.org/PathwayBrowser/#/R-SSC-5218805 PKC autophosphorylates IEA Sus scrofa 456216 R-SSC-5218806 https://reactome.org/PathwayBrowser/#/R-SSC-5218806 FYN autophosphorylates IEA Sus scrofa 456216 R-SSC-5218809 https://reactome.org/PathwayBrowser/#/R-SSC-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Sus scrofa 456216 R-SSC-5218812 https://reactome.org/PathwayBrowser/#/R-SSC-5218812 FYN phosphorylates PAK2 IEA Sus scrofa 456216 R-SSC-5218814 https://reactome.org/PathwayBrowser/#/R-SSC-5218814 PAK2 autophorylates IEA Sus scrofa 456216 R-SSC-5218819 https://reactome.org/PathwayBrowser/#/R-SSC-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-5218820 https://reactome.org/PathwayBrowser/#/R-SSC-5218820 Src kinases phosphorylate VAV IEA Sus scrofa 456216 R-SSC-5218821 https://reactome.org/PathwayBrowser/#/R-SSC-5218821 PDK1 phosphorylates PKC IEA Sus scrofa 456216 R-SSC-5218823 https://reactome.org/PathwayBrowser/#/R-SSC-5218823 PKC phosphorylates sphingosine kinase 1 IEA Sus scrofa 456216 R-SSC-5218826 https://reactome.org/PathwayBrowser/#/R-SSC-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Sus scrofa 456216 R-SSC-5218830 https://reactome.org/PathwayBrowser/#/R-SSC-5218830 SRC-1 phosphorylates PTK2-beta IEA Sus scrofa 456216 R-SSC-5218845 https://reactome.org/PathwayBrowser/#/R-SSC-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Sus scrofa 456216 R-SSC-5218851 https://reactome.org/PathwayBrowser/#/R-SSC-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Sus scrofa 456216 R-SSC-5218854 https://reactome.org/PathwayBrowser/#/R-SSC-5218854 p-Y420-FYN is phosphorylated on S21 IEA Sus scrofa 456216 R-SSC-5218906 https://reactome.org/PathwayBrowser/#/R-SSC-5218906 RIPK3 phosphorylates MLKL IEA Sus scrofa 456216 R-SSC-5218916 https://reactome.org/PathwayBrowser/#/R-SSC-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Sus scrofa 456216 R-SSC-5223313 https://reactome.org/PathwayBrowser/#/R-SSC-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Sus scrofa 456216 R-SSC-5223317 https://reactome.org/PathwayBrowser/#/R-SSC-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Sus scrofa 456216 R-SSC-5229194 https://reactome.org/PathwayBrowser/#/R-SSC-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Sus scrofa 456216 R-SSC-5229343 https://reactome.org/PathwayBrowser/#/R-SSC-5229343 AXIN is phosphorylated in the destruction complex IEA Sus scrofa 456216 R-SSC-5244669 https://reactome.org/PathwayBrowser/#/R-SSC-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Sus scrofa 456216 R-SSC-5251955 https://reactome.org/PathwayBrowser/#/R-SSC-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Sus scrofa 456216 R-SSC-5251959 https://reactome.org/PathwayBrowser/#/R-SSC-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Sus scrofa 456216 R-SSC-5251989 https://reactome.org/PathwayBrowser/#/R-SSC-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Sus scrofa 456216 R-SSC-5252079 https://reactome.org/PathwayBrowser/#/R-SSC-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Sus scrofa 456216 R-SSC-5357429 https://reactome.org/PathwayBrowser/#/R-SSC-5357429 AXL autophosphorylates on Y779 and Y821 IEA Sus scrofa 456216 R-SSC-5357472 https://reactome.org/PathwayBrowser/#/R-SSC-5357472 PAK1-3 autophosphorylates IEA Sus scrofa 456216 R-SSC-5357477 https://reactome.org/PathwayBrowser/#/R-SSC-5357477 PAK1-3 phosphorylates VE-cadherin IEA Sus scrofa 456216 R-SSC-5357831 https://reactome.org/PathwayBrowser/#/R-SSC-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Sus scrofa 456216 R-SSC-5358513 https://reactome.org/PathwayBrowser/#/R-SSC-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Sus scrofa 456216 R-SSC-5358525 https://reactome.org/PathwayBrowser/#/R-SSC-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Sus scrofa 456216 R-SSC-5358912 https://reactome.org/PathwayBrowser/#/R-SSC-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Sus scrofa 456216 R-SSC-5362459 https://reactome.org/PathwayBrowser/#/R-SSC-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Sus scrofa 456216 R-SSC-5444511 https://reactome.org/PathwayBrowser/#/R-SSC-5444511 Formation of MSH2:MSH3 Complex IEA Sus scrofa 456216 R-SSC-5444516 https://reactome.org/PathwayBrowser/#/R-SSC-5444516 Formation of MSH2:MSH6 Complex IEA Sus scrofa 456216 R-SSC-5578777 https://reactome.org/PathwayBrowser/#/R-SSC-5578777 DMPK phosphorylates PLN IEA Sus scrofa 456216 R-SSC-5607722 https://reactome.org/PathwayBrowser/#/R-SSC-5607722 Active NIK phosphorylates IKKA dimer IEA Sus scrofa 456216 R-SSC-5607726 https://reactome.org/PathwayBrowser/#/R-SSC-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Sus scrofa 456216 R-SSC-5607732 https://reactome.org/PathwayBrowser/#/R-SSC-5607732 K63polyUb-TAK1 autophosphorylates IEA Sus scrofa 456216 R-SSC-5607740 https://reactome.org/PathwayBrowser/#/R-SSC-5607740 PKC-delta phosphorylates CARD9 IEA Sus scrofa 456216 R-SSC-5607742 https://reactome.org/PathwayBrowser/#/R-SSC-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Sus scrofa 456216 R-SSC-5607750 https://reactome.org/PathwayBrowser/#/R-SSC-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Sus scrofa 456216 R-SSC-5610720 https://reactome.org/PathwayBrowser/#/R-SSC-5610720 PKA phosphorylates GLI3 IEA Sus scrofa 456216 R-SSC-5610722 https://reactome.org/PathwayBrowser/#/R-SSC-5610722 CK1 phosphorylates p-GLI3 IEA Sus scrofa 456216 R-SSC-5610732 https://reactome.org/PathwayBrowser/#/R-SSC-5610732 GSK3 phosphorylates p-GLI3 IEA Sus scrofa 456216 R-SSC-5617179 https://reactome.org/PathwayBrowser/#/R-SSC-5617179 PRKACA phosphorylates TNNI3 IEA Sus scrofa 456216 R-SSC-5617182 https://reactome.org/PathwayBrowser/#/R-SSC-5617182 PRKACA phosphorylates PLN IEA Sus scrofa 456216 R-SSC-5618085 https://reactome.org/PathwayBrowser/#/R-SSC-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Sus scrofa 456216 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 456216 R-SSC-5618098 https://reactome.org/PathwayBrowser/#/R-SSC-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Sus scrofa 456216 R-SSC-5618105 https://reactome.org/PathwayBrowser/#/R-SSC-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Sus scrofa 456216 R-SSC-5618107 https://reactome.org/PathwayBrowser/#/R-SSC-5618107 ATP binding to HSP90 triggers conformation change IEA Sus scrofa 456216 R-SSC-5618110 https://reactome.org/PathwayBrowser/#/R-SSC-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Sus scrofa 456216 R-SSC-5621355 https://reactome.org/PathwayBrowser/#/R-SSC-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Sus scrofa 456216 R-SSC-5621363 https://reactome.org/PathwayBrowser/#/R-SSC-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Sus scrofa 456216 R-SSC-5621370 https://reactome.org/PathwayBrowser/#/R-SSC-5621370 SYK autophosphorylates IEA Sus scrofa 456216 R-SSC-5623667 https://reactome.org/PathwayBrowser/#/R-SSC-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Sus scrofa 456216 R-SSC-5624473 https://reactome.org/PathwayBrowser/#/R-SSC-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Sus scrofa 456216 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa 456216 R-SSC-5627775 https://reactome.org/PathwayBrowser/#/R-SSC-5627775 Autophosphorylation of PAK1,2,3 IEA Sus scrofa 456216 R-SSC-5635842 https://reactome.org/PathwayBrowser/#/R-SSC-5635842 ULK3 phosphorylates GLI IEA Sus scrofa 456216 R-SSC-5654149 https://reactome.org/PathwayBrowser/#/R-SSC-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Sus scrofa 456216 R-SSC-5654151 https://reactome.org/PathwayBrowser/#/R-SSC-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Sus scrofa 456216 R-SSC-5654418 https://reactome.org/PathwayBrowser/#/R-SSC-5654418 Activated FGFR4 phosphorylates FRS2 IEA Sus scrofa 456216 R-SSC-5654428 https://reactome.org/PathwayBrowser/#/R-SSC-5654428 Activated FGFR4 phosphorylates SHC1 IEA Sus scrofa 456216 R-SSC-5654560 https://reactome.org/PathwayBrowser/#/R-SSC-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Sus scrofa 456216 R-SSC-5654566 https://reactome.org/PathwayBrowser/#/R-SSC-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Sus scrofa 456216 R-SSC-5654575 https://reactome.org/PathwayBrowser/#/R-SSC-5654575 Activated FGFR1 phosphorylates FRS2 IEA Sus scrofa 456216 R-SSC-5654578 https://reactome.org/PathwayBrowser/#/R-SSC-5654578 Activated FGFR1 phosphorylates FRS3 IEA Sus scrofa 456216 R-SSC-5654582 https://reactome.org/PathwayBrowser/#/R-SSC-5654582 Activated FGFR1 phosphorylates SHC1 IEA Sus scrofa 456216 R-SSC-5654587 https://reactome.org/PathwayBrowser/#/R-SSC-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Sus scrofa 456216 R-SSC-5654607 https://reactome.org/PathwayBrowser/#/R-SSC-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Sus scrofa 456216 R-SSC-5654631 https://reactome.org/PathwayBrowser/#/R-SSC-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Sus scrofa 456216 R-SSC-5654653 https://reactome.org/PathwayBrowser/#/R-SSC-5654653 Activated FGFR4 phosphorylates FRS3 IEA Sus scrofa 456216 R-SSC-5654655 https://reactome.org/PathwayBrowser/#/R-SSC-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Sus scrofa 456216 R-SSC-5654690 https://reactome.org/PathwayBrowser/#/R-SSC-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-5654692 https://reactome.org/PathwayBrowser/#/R-SSC-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-5654697 https://reactome.org/PathwayBrowser/#/R-SSC-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-5654701 https://reactome.org/PathwayBrowser/#/R-SSC-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-5654705 https://reactome.org/PathwayBrowser/#/R-SSC-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-5654709 https://reactome.org/PathwayBrowser/#/R-SSC-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-5654714 https://reactome.org/PathwayBrowser/#/R-SSC-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-5654717 https://reactome.org/PathwayBrowser/#/R-SSC-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-5654989 https://reactome.org/PathwayBrowser/#/R-SSC-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Sus scrofa 456216 R-SSC-5662466 https://reactome.org/PathwayBrowser/#/R-SSC-5662466 XYLB phosphorylates D-xylulose IEA Sus scrofa 456216 R-SSC-5665868 https://reactome.org/PathwayBrowser/#/R-SSC-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Sus scrofa 456216 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa 456216 R-SSC-5668545 https://reactome.org/PathwayBrowser/#/R-SSC-5668545 NIK autophosphorylates on T559 IEA Sus scrofa 456216 R-SSC-5668932 https://reactome.org/PathwayBrowser/#/R-SSC-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Sus scrofa 456216 R-SSC-5668947 https://reactome.org/PathwayBrowser/#/R-SSC-5668947 PAK1 phosphorylates myosin phosphatase IEA Sus scrofa 456216 R-SSC-5668984 https://reactome.org/PathwayBrowser/#/R-SSC-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Sus scrofa 456216 R-SSC-5669250 https://reactome.org/PathwayBrowser/#/R-SSC-5669250 PAK1 phosphorylates FLNA IEA Sus scrofa 456216 R-SSC-5671749 https://reactome.org/PathwayBrowser/#/R-SSC-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Sus scrofa 456216 R-SSC-5671763 https://reactome.org/PathwayBrowser/#/R-SSC-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Sus scrofa 456216 R-SSC-5672008 https://reactome.org/PathwayBrowser/#/R-SSC-5672008 Thr-180 of ULK1 is phosphorylated IEA Sus scrofa 456216 R-SSC-5672010 https://reactome.org/PathwayBrowser/#/R-SSC-5672010 Active MTORC1 phosphorylates ULK1 IEA Sus scrofa 456216 R-SSC-5672012 https://reactome.org/PathwayBrowser/#/R-SSC-5672012 Beclin-1 complex phosphorylates PtdIns IEA Sus scrofa 456216 R-SSC-5672027 https://reactome.org/PathwayBrowser/#/R-SSC-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Sus scrofa 456216 R-SSC-5672828 https://reactome.org/PathwayBrowser/#/R-SSC-5672828 mTORC1 phosphorylates AKT1S1 IEA Sus scrofa 456216 R-SSC-5672948 https://reactome.org/PathwayBrowser/#/R-SSC-5672948 MARK3 phosphorylates KSR1 IEA Sus scrofa 456216 R-SSC-5672969 https://reactome.org/PathwayBrowser/#/R-SSC-5672969 Phosphorylation of RAF IEA Sus scrofa 456216 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 456216 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 456216 R-SSC-5673768 https://reactome.org/PathwayBrowser/#/R-SSC-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Sus scrofa 456216 R-SSC-5674130 https://reactome.org/PathwayBrowser/#/R-SSC-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Sus scrofa 456216 R-SSC-5674373 https://reactome.org/PathwayBrowser/#/R-SSC-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Sus scrofa 456216 R-SSC-5675198 https://reactome.org/PathwayBrowser/#/R-SSC-5675198 Activated MAPKs phosphorylate BRAF IEA Sus scrofa 456216 R-SSC-5675868 https://reactome.org/PathwayBrowser/#/R-SSC-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Sus scrofa 456216 R-SSC-5678706 https://reactome.org/PathwayBrowser/#/R-SSC-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Sus scrofa 456216 R-SSC-5678863 https://reactome.org/PathwayBrowser/#/R-SSC-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-5679041 https://reactome.org/PathwayBrowser/#/R-SSC-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-5679205 https://reactome.org/PathwayBrowser/#/R-SSC-5679205 ULK1 phosphorylates Beclin-1 IEA Sus scrofa 456216 R-SSC-5682026 https://reactome.org/PathwayBrowser/#/R-SSC-5682026 MRN bound to shortened telomeres activates ATM IEA Sus scrofa 456216 R-SSC-5682101 https://reactome.org/PathwayBrowser/#/R-SSC-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Sus scrofa 456216 R-SSC-5682285 https://reactome.org/PathwayBrowser/#/R-SSC-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-5682598 https://reactome.org/PathwayBrowser/#/R-SSC-5682598 ATM phosphorylates HERC2 IEA Sus scrofa 456216 R-SSC-5682983 https://reactome.org/PathwayBrowser/#/R-SSC-5682983 ATM phosphorylates WHSC1 IEA Sus scrofa 456216 R-SSC-5683425 https://reactome.org/PathwayBrowser/#/R-SSC-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Sus scrofa 456216 R-SSC-5683714 https://reactome.org/PathwayBrowser/#/R-SSC-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Sus scrofa 456216 R-SSC-5683792 https://reactome.org/PathwayBrowser/#/R-SSC-5683792 p-T68-CHEK2 autophosphorylates IEA Sus scrofa 456216 R-SSC-5683801 https://reactome.org/PathwayBrowser/#/R-SSC-5683801 CHEK2 phosphorylates BRCA1 IEA Sus scrofa 456216 R-SSC-5683964 https://reactome.org/PathwayBrowser/#/R-SSC-5683964 ATM phosphorylates EYA1-4 IEA Sus scrofa 456216 R-SSC-5684096 https://reactome.org/PathwayBrowser/#/R-SSC-5684096 CDK2 phosphorylates RBBP8 IEA Sus scrofa 456216 R-SSC-5684140 https://reactome.org/PathwayBrowser/#/R-SSC-5684140 ATM phosphorylates RBBP8 IEA Sus scrofa 456216 R-SSC-5684261 https://reactome.org/PathwayBrowser/#/R-SSC-5684261 MAP3K8 is phosphorylated IEA Sus scrofa 456216 R-SSC-5684267 https://reactome.org/PathwayBrowser/#/R-SSC-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex IEA Sus scrofa 456216 R-SSC-5684275 https://reactome.org/PathwayBrowser/#/R-SSC-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 IEA Sus scrofa 456216 R-SSC-5684806 https://reactome.org/PathwayBrowser/#/R-SSC-5684806 Unknown kinase phosphorylates CLEC1B dimer:PDPN IEA Sus scrofa 456216 R-SSC-5684887 https://reactome.org/PathwayBrowser/#/R-SSC-5684887 Activation of CHEK1 at resected DNA DSBs IEA Sus scrofa 456216 R-SSC-5685156 https://reactome.org/PathwayBrowser/#/R-SSC-5685156 ATR phosphorylates RPA2 IEA Sus scrofa 456216 R-SSC-5685230 https://reactome.org/PathwayBrowser/#/R-SSC-5685230 CHEK1 phosphorylates RAD51 IEA Sus scrofa 456216 R-SSC-5686578 https://reactome.org/PathwayBrowser/#/R-SSC-5686578 Activated ATM phosphorylates ABL1 IEA Sus scrofa 456216 R-SSC-5686587 https://reactome.org/PathwayBrowser/#/R-SSC-5686587 ABL1 phosphorylates RAD52 IEA Sus scrofa 456216 R-SSC-5686704 https://reactome.org/PathwayBrowser/#/R-SSC-5686704 Activated ATM phosphorylates DCLRE1C IEA Sus scrofa 456216 R-SSC-5687086 https://reactome.org/PathwayBrowser/#/R-SSC-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Sus scrofa 456216 R-SSC-5687088 https://reactome.org/PathwayBrowser/#/R-SSC-5687088 PKA phosphorylates MAPKAPK5 IEA Sus scrofa 456216 R-SSC-5687090 https://reactome.org/PathwayBrowser/#/R-SSC-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Sus scrofa 456216 R-SSC-5687094 https://reactome.org/PathwayBrowser/#/R-SSC-5687094 p-S MAPK6,4 phosphorylate MAPKAPK5 IEA Sus scrofa 456216 R-SSC-5687101 https://reactome.org/PathwayBrowser/#/R-SSC-5687101 p-T182 MAPKAPK5 phosphorylates FOXO3 IEA Sus scrofa 456216 R-SSC-5687121 https://reactome.org/PathwayBrowser/#/R-SSC-5687121 p-S MAPKAPK5 phosphorylates HSPB1 IEA Sus scrofa 456216 R-SSC-5687183 https://reactome.org/PathwayBrowser/#/R-SSC-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Sus scrofa 456216 R-SSC-5690250 https://reactome.org/PathwayBrowser/#/R-SSC-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Sus scrofa 456216 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa 456216 R-SSC-5690996 https://reactome.org/PathwayBrowser/#/R-SSC-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Sus scrofa 456216 R-SSC-5692462 https://reactome.org/PathwayBrowser/#/R-SSC-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Sus scrofa 456216 R-SSC-5692480 https://reactome.org/PathwayBrowser/#/R-SSC-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Sus scrofa 456216 R-SSC-5692755 https://reactome.org/PathwayBrowser/#/R-SSC-5692755 CDK1 phosphorylates MAPK6 IEA Sus scrofa 456216 R-SSC-5692775 https://reactome.org/PathwayBrowser/#/R-SSC-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Sus scrofa 456216 R-SSC-5692779 https://reactome.org/PathwayBrowser/#/R-SSC-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Sus scrofa 456216 R-SSC-5693148 https://reactome.org/PathwayBrowser/#/R-SSC-5693148 BCKDK phosphorylates BCKDH IEA Sus scrofa 456216 R-SSC-5693536 https://reactome.org/PathwayBrowser/#/R-SSC-5693536 ATM phosphorylates MDC1 IEA Sus scrofa 456216 R-SSC-5693540 https://reactome.org/PathwayBrowser/#/R-SSC-5693540 MRN activates ATM IEA Sus scrofa 456216 R-SSC-5693549 https://reactome.org/PathwayBrowser/#/R-SSC-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Sus scrofa 456216 R-SSC-5693551 https://reactome.org/PathwayBrowser/#/R-SSC-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Sus scrofa 456216 R-SSC-5693575 https://reactome.org/PathwayBrowser/#/R-SSC-5693575 DNA-PKcs autophosphorylates IEA Sus scrofa 456216 R-SSC-5693598 https://reactome.org/PathwayBrowser/#/R-SSC-5693598 ATM phosphorylates NBN IEA Sus scrofa 456216 R-SSC-5693609 https://reactome.org/PathwayBrowser/#/R-SSC-5693609 ATM phosphorylates TP53 at S15 IEA Sus scrofa 456216 R-SSC-5696021 https://reactome.org/PathwayBrowser/#/R-SSC-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Sus scrofa 456216 R-SSC-5696074 https://reactome.org/PathwayBrowser/#/R-SSC-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Sus scrofa 456216 R-SSC-5696839 https://reactome.org/PathwayBrowser/#/R-SSC-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Sus scrofa 456216 R-SSC-6782131 https://reactome.org/PathwayBrowser/#/R-SSC-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa 456216 R-SSC-6784006 https://reactome.org/PathwayBrowser/#/R-SSC-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Sus scrofa 456216 R-SSC-6784319 https://reactome.org/PathwayBrowser/#/R-SSC-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Sus scrofa 456216 R-SSC-6784324 https://reactome.org/PathwayBrowser/#/R-SSC-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Sus scrofa 456216 R-SSC-6786050 https://reactome.org/PathwayBrowser/#/R-SSC-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Sus scrofa 456216 R-SSC-6786095 https://reactome.org/PathwayBrowser/#/R-SSC-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Sus scrofa 456216 R-SSC-6786096 https://reactome.org/PathwayBrowser/#/R-SSC-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Sus scrofa 456216 R-SSC-6786245 https://reactome.org/PathwayBrowser/#/R-SSC-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Sus scrofa 456216 R-SSC-6787540 https://reactome.org/PathwayBrowser/#/R-SSC-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Sus scrofa 456216 R-SSC-6788392 https://reactome.org/PathwayBrowser/#/R-SSC-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Sus scrofa 456216 R-SSC-6788582 https://reactome.org/PathwayBrowser/#/R-SSC-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Sus scrofa 456216 R-SSC-6788798 https://reactome.org/PathwayBrowser/#/R-SSC-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 456216 R-SSC-6788810 https://reactome.org/PathwayBrowser/#/R-SSC-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 456216 R-SSC-6788855 https://reactome.org/PathwayBrowser/#/R-SSC-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Sus scrofa 456216 R-SSC-6788867 https://reactome.org/PathwayBrowser/#/R-SSC-6788867 FN3K phosphorylates ketosamines IEA Sus scrofa 456216 R-SSC-6793661 https://reactome.org/PathwayBrowser/#/R-SSC-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Sus scrofa 456216 R-SSC-6795290 https://reactome.org/PathwayBrowser/#/R-SSC-6795290 TORC2 complex phosphorylates SGK1 IEA Sus scrofa 456216 R-SSC-6795460 https://reactome.org/PathwayBrowser/#/R-SSC-6795460 SGK1 phosphorylates MDM2 IEA Sus scrofa 456216 R-SSC-6795473 https://reactome.org/PathwayBrowser/#/R-SSC-6795473 PDPK1 phosphorylates SGK1 IEA Sus scrofa 456216 R-SSC-6797606 https://reactome.org/PathwayBrowser/#/R-SSC-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Sus scrofa 456216 R-SSC-6798174 https://reactome.org/PathwayBrowser/#/R-SSC-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Sus scrofa 456216 R-SSC-6798372 https://reactome.org/PathwayBrowser/#/R-SSC-6798372 ATM phosphorylates DYRK2 IEA Sus scrofa 456216 R-SSC-6798374 https://reactome.org/PathwayBrowser/#/R-SSC-6798374 DYRK2 phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6799097 https://reactome.org/PathwayBrowser/#/R-SSC-6799097 ATM phosphorylates ZNF420 IEA Sus scrofa 456216 R-SSC-6799246 https://reactome.org/PathwayBrowser/#/R-SSC-6799246 CHEK1 phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6799332 https://reactome.org/PathwayBrowser/#/R-SSC-6799332 ATR phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6799409 https://reactome.org/PathwayBrowser/#/R-SSC-6799409 HIPK2 phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6799495 https://reactome.org/PathwayBrowser/#/R-SSC-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Sus scrofa 456216 R-SSC-6800490 https://reactome.org/PathwayBrowser/#/R-SSC-6800490 ATM phosphorylates PIDD1 IEA Sus scrofa 456216 R-SSC-6801342 https://reactome.org/PathwayBrowser/#/R-SSC-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Sus scrofa 456216 R-SSC-6801456 https://reactome.org/PathwayBrowser/#/R-SSC-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Sus scrofa 456216 R-SSC-6801666 https://reactome.org/PathwayBrowser/#/R-SSC-6801666 PLK2 phosphorylates CENPJ IEA Sus scrofa 456216 R-SSC-6801675 https://reactome.org/PathwayBrowser/#/R-SSC-6801675 PLK2 phosphorylates NPM1 IEA Sus scrofa 456216 R-SSC-6802973 https://reactome.org/PathwayBrowser/#/R-SSC-6802973 PLK3 phosphorylates CDC25C IEA Sus scrofa 456216 R-SSC-6803545 https://reactome.org/PathwayBrowser/#/R-SSC-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Sus scrofa 456216 R-SSC-6803771 https://reactome.org/PathwayBrowser/#/R-SSC-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Sus scrofa 456216 R-SSC-6804266 https://reactome.org/PathwayBrowser/#/R-SSC-6804266 CHEK2 phosphorylates TTC5 IEA Sus scrofa 456216 R-SSC-6804276 https://reactome.org/PathwayBrowser/#/R-SSC-6804276 ATM phosphorylates TTC5 IEA Sus scrofa 456216 R-SSC-6804955 https://reactome.org/PathwayBrowser/#/R-SSC-6804955 ATM phosphorylates MDM2 IEA Sus scrofa 456216 R-SSC-6805059 https://reactome.org/PathwayBrowser/#/R-SSC-6805059 CK2:FACT phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6805103 https://reactome.org/PathwayBrowser/#/R-SSC-6805103 AURKA phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6805109 https://reactome.org/PathwayBrowser/#/R-SSC-6805109 CDK2 phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6805126 https://reactome.org/PathwayBrowser/#/R-SSC-6805126 AURKB phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6805276 https://reactome.org/PathwayBrowser/#/R-SSC-6805276 CDK5 phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6805285 https://reactome.org/PathwayBrowser/#/R-SSC-6805285 PLK3 phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6805399 https://reactome.org/PathwayBrowser/#/R-SSC-6805399 TAF1 phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6805470 https://reactome.org/PathwayBrowser/#/R-SSC-6805470 AMPK phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6805479 https://reactome.org/PathwayBrowser/#/R-SSC-6805479 TP53RK phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-6805507 https://reactome.org/PathwayBrowser/#/R-SSC-6805507 APAF1 binds AVEN IEA Sus scrofa 456216 R-SSC-6806877 https://reactome.org/PathwayBrowser/#/R-SSC-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Sus scrofa 456216 R-SSC-6806967 https://reactome.org/PathwayBrowser/#/R-SSC-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Sus scrofa 456216 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 456216 R-SSC-6807868 https://reactome.org/PathwayBrowser/#/R-SSC-6807868 GBF1 stimulates ARF nucleotide exchange IEA Sus scrofa 456216 R-SSC-6810233 https://reactome.org/PathwayBrowser/#/R-SSC-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Sus scrofa 456216 R-SSC-6810472 https://reactome.org/PathwayBrowser/#/R-SSC-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Sus scrofa 456216 R-SSC-6811454 https://reactome.org/PathwayBrowser/#/R-SSC-6811454 MAPKs phosphorylate PP2A IEA Sus scrofa 456216 R-SSC-6811522 https://reactome.org/PathwayBrowser/#/R-SSC-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Sus scrofa 456216 R-SSC-6814119 https://reactome.org/PathwayBrowser/#/R-SSC-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Sus scrofa 456216 R-SSC-6814120 https://reactome.org/PathwayBrowser/#/R-SSC-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Sus scrofa 456216 R-SSC-6814121 https://reactome.org/PathwayBrowser/#/R-SSC-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Sus scrofa 456216 R-SSC-6814124 https://reactome.org/PathwayBrowser/#/R-SSC-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Sus scrofa 456216 R-SSC-6814409 https://reactome.org/PathwayBrowser/#/R-SSC-6814409 CK2 phosphorylates PDCL IEA Sus scrofa 456216 R-SSC-68944 https://reactome.org/PathwayBrowser/#/R-SSC-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Sus scrofa 456216 R-SSC-68954 https://reactome.org/PathwayBrowser/#/R-SSC-68954 Mcm2-7 is phosphorylated by DDK IEA Sus scrofa 456216 R-SSC-69005 https://reactome.org/PathwayBrowser/#/R-SSC-69005 Cdc6 protein is phosphorylated by CDK IEA Sus scrofa 456216 R-SSC-69063 https://reactome.org/PathwayBrowser/#/R-SSC-69063 Loading of PCNA - Sliding Clamp Formation IEA Sus scrofa 456216 R-SSC-69195 https://reactome.org/PathwayBrowser/#/R-SSC-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Sus scrofa 456216 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 456216 R-SSC-69604 https://reactome.org/PathwayBrowser/#/R-SSC-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Sus scrofa 456216 R-SSC-69608 https://reactome.org/PathwayBrowser/#/R-SSC-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Sus scrofa 456216 R-SSC-69685 https://reactome.org/PathwayBrowser/#/R-SSC-69685 CHEK2 phosphorylates TP53 IEA Sus scrofa 456216 R-SSC-69891 https://reactome.org/PathwayBrowser/#/R-SSC-69891 Phosphorylation and activation of CHEK2 by ATM IEA Sus scrofa 456216 R-SSC-70333 https://reactome.org/PathwayBrowser/#/R-SSC-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Sus scrofa 456216 R-SSC-70349 https://reactome.org/PathwayBrowser/#/R-SSC-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Sus scrofa 456216 R-SSC-70355 https://reactome.org/PathwayBrowser/#/R-SSC-70355 GALK1 phosphorylates Gal to Gal1P IEA Sus scrofa 456216 R-SSC-70420 https://reactome.org/PathwayBrowser/#/R-SSC-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Sus scrofa 456216 R-SSC-70467 https://reactome.org/PathwayBrowser/#/R-SSC-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Sus scrofa 456216 R-SSC-70486 https://reactome.org/PathwayBrowser/#/R-SSC-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Sus scrofa 456216 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 456216 R-SSC-70555 https://reactome.org/PathwayBrowser/#/R-SSC-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Sus scrofa 456216 R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Sus scrofa 456216 R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Sus scrofa 456216 R-SSC-70606 https://reactome.org/PathwayBrowser/#/R-SSC-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Sus scrofa 456216 R-SSC-70773 https://reactome.org/PathwayBrowser/#/R-SSC-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Sus scrofa 456216 R-SSC-70967 https://reactome.org/PathwayBrowser/#/R-SSC-70967 IDH3 complex decarboxylates isocitrate IEA Sus scrofa 456216 R-SSC-70997 https://reactome.org/PathwayBrowser/#/R-SSC-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Sus scrofa 456216 R-SSC-71031 https://reactome.org/PathwayBrowser/#/R-SSC-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Sus scrofa 456216 R-SSC-71401 https://reactome.org/PathwayBrowser/#/R-SSC-71401 OGDH dimer decarboxylates 2-OG IEA Sus scrofa 456216 R-SSC-71541 https://reactome.org/PathwayBrowser/#/R-SSC-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Sus scrofa 456216 R-SSC-71588 https://reactome.org/PathwayBrowser/#/R-SSC-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Sus scrofa 456216 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 456216 R-SSC-71802 https://reactome.org/PathwayBrowser/#/R-SSC-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Sus scrofa 456216 R-SSC-71850 https://reactome.org/PathwayBrowser/#/R-SSC-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Sus scrofa 456216 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa 456216 R-SSC-727819 https://reactome.org/PathwayBrowser/#/R-SSC-727819 TAK1 phosphorylates MKK6 IEA Sus scrofa 456216 R-SSC-73548 https://reactome.org/PathwayBrowser/#/R-SSC-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Sus scrofa 456216 R-SSC-73577 https://reactome.org/PathwayBrowser/#/R-SSC-73577 CAD hexamer transforms L-Gln to CAP IEA Sus scrofa 456216 R-SSC-73599 https://reactome.org/PathwayBrowser/#/R-SSC-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Sus scrofa 456216 R-SSC-73632 https://reactome.org/PathwayBrowser/#/R-SSC-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Sus scrofa 456216 R-SSC-73635 https://reactome.org/PathwayBrowser/#/R-SSC-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Sus scrofa 456216 R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa 456216 R-SSC-73722 https://reactome.org/PathwayBrowser/#/R-SSC-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Sus scrofa 456216 R-SSC-73788 https://reactome.org/PathwayBrowser/#/R-SSC-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Sus scrofa 456216 R-SSC-73805 https://reactome.org/PathwayBrowser/#/R-SSC-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Sus scrofa 456216 R-SSC-73810 https://reactome.org/PathwayBrowser/#/R-SSC-73810 FGAM + ATP => AIR + ADP + Pi IEA Sus scrofa 456216 R-SSC-73814 https://reactome.org/PathwayBrowser/#/R-SSC-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Sus scrofa 456216 R-SSC-74207 https://reactome.org/PathwayBrowser/#/R-SSC-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Sus scrofa 456216 R-SSC-74220 https://reactome.org/PathwayBrowser/#/R-SSC-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Sus scrofa 456216 R-SSC-74711 https://reactome.org/PathwayBrowser/#/R-SSC-74711 Phosphorylation of IRS IEA Sus scrofa 456216 R-SSC-74715 https://reactome.org/PathwayBrowser/#/R-SSC-74715 Autophosphorylation of insulin receptor IEA Sus scrofa 456216 R-SSC-74742 https://reactome.org/PathwayBrowser/#/R-SSC-74742 Phosphorylation of SHC1 IEA Sus scrofa 456216 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 456216 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 456216 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 456216 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 456216 R-SSC-75010 https://reactome.org/PathwayBrowser/#/R-SSC-75010 Phosphorylation of Cdc25C at Ser 216 by Chk1 IEA Sus scrofa 456216 R-SSC-75125 https://reactome.org/PathwayBrowser/#/R-SSC-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Sus scrofa 456216 R-SSC-75126 https://reactome.org/PathwayBrowser/#/R-SSC-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Sus scrofa 456216 R-SSC-75809 https://reactome.org/PathwayBrowser/#/R-SSC-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Sus scrofa 456216 R-SSC-75848 https://reactome.org/PathwayBrowser/#/R-SSC-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Sus scrofa 456216 R-SSC-75851 https://reactome.org/PathwayBrowser/#/R-SSC-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 456216 R-SSC-75887 https://reactome.org/PathwayBrowser/#/R-SSC-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Sus scrofa 456216 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa 456216 R-SSC-77071 https://reactome.org/PathwayBrowser/#/R-SSC-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Sus scrofa 456216 R-SSC-873918 https://reactome.org/PathwayBrowser/#/R-SSC-873918 Transphosphorylation of JAK1 IEA Sus scrofa 456216 R-SSC-873919 https://reactome.org/PathwayBrowser/#/R-SSC-873919 Phosphorylation of JAK2 IEA Sus scrofa 456216 R-SSC-873922 https://reactome.org/PathwayBrowser/#/R-SSC-873922 Phosphorylation of STAT1 by JAK kinases IEA Sus scrofa 456216 R-SSC-873924 https://reactome.org/PathwayBrowser/#/R-SSC-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Sus scrofa 456216 R-SSC-879907 https://reactome.org/PathwayBrowser/#/R-SSC-879907 Tyrosine kinases phosphorylate the receptor IEA Sus scrofa 456216 R-SSC-879909 https://reactome.org/PathwayBrowser/#/R-SSC-879909 Activation of STAT5a/b by JAK2 IEA Sus scrofa 456216 R-SSC-879910 https://reactome.org/PathwayBrowser/#/R-SSC-879910 JAK2 is phosphorylated, activated IEA Sus scrofa 456216 R-SSC-8847638 https://reactome.org/PathwayBrowser/#/R-SSC-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Sus scrofa 456216 R-SSC-8847977 https://reactome.org/PathwayBrowser/#/R-SSC-8847977 FRK phosphorylates PTEN IEA Sus scrofa 456216 R-SSC-8848005 https://reactome.org/PathwayBrowser/#/R-SSC-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Sus scrofa 456216 R-SSC-8848053 https://reactome.org/PathwayBrowser/#/R-SSC-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Sus scrofa 456216 R-SSC-8848077 https://reactome.org/PathwayBrowser/#/R-SSC-8848077 PTK6 phosphorylates STAP2 IEA Sus scrofa 456216 R-SSC-8848124 https://reactome.org/PathwayBrowser/#/R-SSC-8848124 PTK6 phosphorylates STAT3 IEA Sus scrofa 456216 R-SSC-8848436 https://reactome.org/PathwayBrowser/#/R-SSC-8848436 PTK6 phosphorylates CDKN1B IEA Sus scrofa 456216 R-SSC-8848606 https://reactome.org/PathwayBrowser/#/R-SSC-8848606 PTK6 phosphorylates PXN IEA Sus scrofa 456216 R-SSC-8848726 https://reactome.org/PathwayBrowser/#/R-SSC-8848726 PTK6 phosphorylates BCAR1 IEA Sus scrofa 456216 R-SSC-8848776 https://reactome.org/PathwayBrowser/#/R-SSC-8848776 PTK6 phosphorylates DOK1 IEA Sus scrofa 456216 R-SSC-8848818 https://reactome.org/PathwayBrowser/#/R-SSC-8848818 PTK6 phosphorylates CBL IEA Sus scrofa 456216 R-SSC-8848873 https://reactome.org/PathwayBrowser/#/R-SSC-8848873 PTK6 phosphorylates ARAP1 IEA Sus scrofa 456216 R-SSC-8848975 https://reactome.org/PathwayBrowser/#/R-SSC-8848975 PTK6 phosphorylates KHDRBS1 IEA Sus scrofa 456216 R-SSC-8849032 https://reactome.org/PathwayBrowser/#/R-SSC-8849032 PTK6 phosphorylates KHDRBS2 IEA Sus scrofa 456216 R-SSC-8849042 https://reactome.org/PathwayBrowser/#/R-SSC-8849042 PTK6 phosphorylates KHDRBS3 IEA Sus scrofa 456216 R-SSC-8849068 https://reactome.org/PathwayBrowser/#/R-SSC-8849068 PTK6 phosphorylates ARHGAP35 IEA Sus scrofa 456216 R-SSC-8849102 https://reactome.org/PathwayBrowser/#/R-SSC-8849102 SRMS phosphorylates PTK6 IEA Sus scrofa 456216 R-SSC-8849463 https://reactome.org/PathwayBrowser/#/R-SSC-8849463 PTK6 phosphorylates SFPQ IEA Sus scrofa 456216 R-SSC-8850527 https://reactome.org/PathwayBrowser/#/R-SSC-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Sus scrofa 456216 R-SSC-8850529 https://reactome.org/PathwayBrowser/#/R-SSC-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Sus scrofa 456216 R-SSC-8850534 https://reactome.org/PathwayBrowser/#/R-SSC-8850534 PDCL promotes G-protein beta 5 folding IEA Sus scrofa 456216 R-SSC-8850539 https://reactome.org/PathwayBrowser/#/R-SSC-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Sus scrofa 456216 R-SSC-8850945 https://reactome.org/PathwayBrowser/#/R-SSC-8850945 Casein kinase II phosphorylates PTEN IEA Sus scrofa 456216 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 456216 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 456216 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 456216 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 456216 R-SSC-8851797 https://reactome.org/PathwayBrowser/#/R-SSC-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Sus scrofa 456216 R-SSC-8851890 https://reactome.org/PathwayBrowser/#/R-SSC-8851890 MET phosphorylates SHC1-2 IEA Sus scrofa 456216 R-SSC-8851933 https://reactome.org/PathwayBrowser/#/R-SSC-8851933 MET phosphorylates GAB1 IEA Sus scrofa 456216 R-SSC-8852019 https://reactome.org/PathwayBrowser/#/R-SSC-8852019 MET bound PI3K generates PIP3 IEA Sus scrofa 456216 R-SSC-8852306 https://reactome.org/PathwayBrowser/#/R-SSC-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Sus scrofa 456216 R-SSC-8852317 https://reactome.org/PathwayBrowser/#/R-SSC-8852317 PLK1 phosphorylates GTSE1 IEA Sus scrofa 456216 R-SSC-8852552 https://reactome.org/PathwayBrowser/#/R-SSC-8852552 MST1R autophosphorylates IEA Sus scrofa 456216 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa 456216 R-SSC-8853444 https://reactome.org/PathwayBrowser/#/R-SSC-8853444 AURKA phosphorylates PHLDA1 IEA Sus scrofa 456216 R-SSC-8853774 https://reactome.org/PathwayBrowser/#/R-SSC-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Sus scrofa 456216 R-SSC-8853792 https://reactome.org/PathwayBrowser/#/R-SSC-8853792 RET tyrosine phosphorylation IEA Sus scrofa 456216 R-SSC-8854908 https://reactome.org/PathwayBrowser/#/R-SSC-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Sus scrofa 456216 R-SSC-8855237 https://reactome.org/PathwayBrowser/#/R-SSC-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Sus scrofa 456216 R-SSC-8856813 https://reactome.org/PathwayBrowser/#/R-SSC-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Sus scrofa 456216 R-SSC-8857555 https://reactome.org/PathwayBrowser/#/R-SSC-8857555 EGFR phosphorylates GPNMB IEA Sus scrofa 456216 R-SSC-8857577 https://reactome.org/PathwayBrowser/#/R-SSC-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Sus scrofa 456216 R-SSC-8857583 https://reactome.org/PathwayBrowser/#/R-SSC-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Sus scrofa 456216 R-SSC-8857925 https://reactome.org/PathwayBrowser/#/R-SSC-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Sus scrofa 456216 R-SSC-8865774 https://reactome.org/PathwayBrowser/#/R-SSC-8865774 TTLLs polyglutamylate tubulin IEA Sus scrofa 456216 R-SSC-8866268 https://reactome.org/PathwayBrowser/#/R-SSC-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Sus scrofa 456216 R-SSC-8866542 https://reactome.org/PathwayBrowser/#/R-SSC-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Sus scrofa 456216 R-SSC-8867041 https://reactome.org/PathwayBrowser/#/R-SSC-8867041 EGFR phosphorylates EPS15 IEA Sus scrofa 456216 R-SSC-8867370 https://reactome.org/PathwayBrowser/#/R-SSC-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Sus scrofa 456216 R-SSC-8868066 https://reactome.org/PathwayBrowser/#/R-SSC-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Sus scrofa 456216 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 456216 R-SSC-8868118 https://reactome.org/PathwayBrowser/#/R-SSC-8868118 MAPK12 phosphorylates PTPN3 IEA Sus scrofa 456216 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 456216 R-SSC-8869606 https://reactome.org/PathwayBrowser/#/R-SSC-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Sus scrofa 456216 R-SSC-8869607 https://reactome.org/PathwayBrowser/#/R-SSC-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Sus scrofa 456216 R-SSC-8869627 https://reactome.org/PathwayBrowser/#/R-SSC-8869627 NMRK2 phosphorylates NR to yield NMN IEA Sus scrofa 456216 R-SSC-8869633 https://reactome.org/PathwayBrowser/#/R-SSC-8869633 NMRK1 phosphorylates NR to yield NMN IEA Sus scrofa 456216 R-SSC-8871373 https://reactome.org/PathwayBrowser/#/R-SSC-8871373 BMX phosphorylates RUFY1 IEA Sus scrofa 456216 R-SSC-8873929 https://reactome.org/PathwayBrowser/#/R-SSC-8873929 Casein kinase II phosphorylates STARD10 IEA Sus scrofa 456216 R-SSC-8874080 https://reactome.org/PathwayBrowser/#/R-SSC-8874080 SRC phosphorylates PTK2 IEA Sus scrofa 456216 R-SSC-8874082 https://reactome.org/PathwayBrowser/#/R-SSC-8874082 MET phosphorylates PTK2 IEA Sus scrofa 456216 R-SSC-8875451 https://reactome.org/PathwayBrowser/#/R-SSC-8875451 MET phosphorylates CBL IEA Sus scrofa 456216 R-SSC-8875817 https://reactome.org/PathwayBrowser/#/R-SSC-8875817 MET phosphorylates STAT3 IEA Sus scrofa 456216 R-SSC-8876446 https://reactome.org/PathwayBrowser/#/R-SSC-8876446 p-ULK1 phosphorylates DENND3 IEA Sus scrofa 456216 R-SSC-8876889 https://reactome.org/PathwayBrowser/#/R-SSC-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 456216 R-SSC-8877691 https://reactome.org/PathwayBrowser/#/R-SSC-8877691 MAP2K6 phosphorylates PIP4K2B IEA Sus scrofa 456216 R-SSC-8878050 https://reactome.org/PathwayBrowser/#/R-SSC-8878050 HIPK2 phosphorylates RUNX1 and EP300 IEA Sus scrofa 456216 R-SSC-8878054 https://reactome.org/PathwayBrowser/#/R-SSC-8878054 HIPK2 phosphorylates RUNX1 IEA Sus scrofa 456216 R-SSC-8931653 https://reactome.org/PathwayBrowser/#/R-SSC-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Sus scrofa 456216 R-SSC-8934446 https://reactome.org/PathwayBrowser/#/R-SSC-8934446 Activated PKC phosphorylates SHC1 IEA Sus scrofa 456216 R-SSC-8937807 https://reactome.org/PathwayBrowser/#/R-SSC-8937807 SRC phosphorylates RUNX3 IEA Sus scrofa 456216 R-SSC-8940100 https://reactome.org/PathwayBrowser/#/R-SSC-8940100 CDK1 phosphorylates VCPIP1 IEA Sus scrofa 456216 R-SSC-8942575 https://reactome.org/PathwayBrowser/#/R-SSC-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Sus scrofa 456216 R-SSC-8942607 https://reactome.org/PathwayBrowser/#/R-SSC-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Sus scrofa 456216 R-SSC-8942836 https://reactome.org/PathwayBrowser/#/R-SSC-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Sus scrofa 456216 R-SSC-8944454 https://reactome.org/PathwayBrowser/#/R-SSC-8944454 mTORC1 phosphorylates MAF1 IEA Sus scrofa 456216 R-SSC-8948039 https://reactome.org/PathwayBrowser/#/R-SSC-8948039 FUNDC1 is phosphorylated by CK2 IEA Sus scrofa 456216 R-SSC-8948143 https://reactome.org/PathwayBrowser/#/R-SSC-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 IEA Sus scrofa 456216 R-SSC-8948146 https://reactome.org/PathwayBrowser/#/R-SSC-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Sus scrofa 456216 R-SSC-8950269 https://reactome.org/PathwayBrowser/#/R-SSC-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Sus scrofa 456216 R-SSC-8950340 https://reactome.org/PathwayBrowser/#/R-SSC-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Sus scrofa 456216 R-SSC-8950405 https://reactome.org/PathwayBrowser/#/R-SSC-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Sus scrofa 456216 R-SSC-8950423 https://reactome.org/PathwayBrowser/#/R-SSC-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Sus scrofa 456216 R-SSC-8950453 https://reactome.org/PathwayBrowser/#/R-SSC-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Sus scrofa 456216 R-SSC-8950485 https://reactome.org/PathwayBrowser/#/R-SSC-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Sus scrofa 456216 R-SSC-8950537 https://reactome.org/PathwayBrowser/#/R-SSC-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Sus scrofa 456216 R-SSC-8950757 https://reactome.org/PathwayBrowser/#/R-SSC-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Sus scrofa 456216 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa 456216 R-SSC-8954327 https://reactome.org/PathwayBrowser/#/R-SSC-8954327 UCKL1 phosphorylates urindine, cytidine IEA Sus scrofa 456216 R-SSC-8955030 https://reactome.org/PathwayBrowser/#/R-SSC-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Sus scrofa 456216 R-SSC-8955844 https://reactome.org/PathwayBrowser/#/R-SSC-8955844 RBKS phosphorylates ribose to R5P IEA Sus scrofa 456216 R-SSC-8956659 https://reactome.org/PathwayBrowser/#/R-SSC-8956659 ABL1 phosphorylates YAP1 IEA Sus scrofa 456216 R-SSC-8959719 https://reactome.org/PathwayBrowser/#/R-SSC-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Sus scrofa 456216 R-SSC-8964242 https://reactome.org/PathwayBrowser/#/R-SSC-8964242 G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC IEA Sus scrofa 456216 R-SSC-8982163 https://reactome.org/PathwayBrowser/#/R-SSC-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Sus scrofa 456216 R-SSC-8983059 https://reactome.org/PathwayBrowser/#/R-SSC-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Sus scrofa 456216 R-SSC-8983063 https://reactome.org/PathwayBrowser/#/R-SSC-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Sus scrofa 456216 R-SSC-8983300 https://reactome.org/PathwayBrowser/#/R-SSC-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Sus scrofa 456216 R-SSC-8983371 https://reactome.org/PathwayBrowser/#/R-SSC-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Sus scrofa 456216 R-SSC-8983834 https://reactome.org/PathwayBrowser/#/R-SSC-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Sus scrofa 456216 R-SSC-8983835 https://reactome.org/PathwayBrowser/#/R-SSC-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Sus scrofa 456216 R-SSC-8983870 https://reactome.org/PathwayBrowser/#/R-SSC-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Sus scrofa 456216 R-SSC-8983872 https://reactome.org/PathwayBrowser/#/R-SSC-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Sus scrofa 456216 R-SSC-8984012 https://reactome.org/PathwayBrowser/#/R-SSC-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Sus scrofa 456216 R-SSC-8984014 https://reactome.org/PathwayBrowser/#/R-SSC-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Sus scrofa 456216 R-SSC-8985914 https://reactome.org/PathwayBrowser/#/R-SSC-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Sus scrofa 456216 R-SSC-8985973 https://reactome.org/PathwayBrowser/#/R-SSC-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Sus scrofa 456216 R-SSC-8985988 https://reactome.org/PathwayBrowser/#/R-SSC-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Sus scrofa 456216 R-SSC-8986985 https://reactome.org/PathwayBrowser/#/R-SSC-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Sus scrofa 456216 R-SSC-8986994 https://reactome.org/PathwayBrowser/#/R-SSC-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Sus scrofa 456216 R-SSC-8986995 https://reactome.org/PathwayBrowser/#/R-SSC-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Sus scrofa 456216 R-SSC-8987012 https://reactome.org/PathwayBrowser/#/R-SSC-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Sus scrofa 456216 R-SSC-8987040 https://reactome.org/PathwayBrowser/#/R-SSC-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Sus scrofa 456216 R-SSC-8987042 https://reactome.org/PathwayBrowser/#/R-SSC-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Sus scrofa 456216 R-SSC-8987070 https://reactome.org/PathwayBrowser/#/R-SSC-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Sus scrofa 456216 R-SSC-8987084 https://reactome.org/PathwayBrowser/#/R-SSC-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Sus scrofa 456216 R-SSC-8987096 https://reactome.org/PathwayBrowser/#/R-SSC-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Sus scrofa 456216 R-SSC-8987129 https://reactome.org/PathwayBrowser/#/R-SSC-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Sus scrofa 456216 R-SSC-8987141 https://reactome.org/PathwayBrowser/#/R-SSC-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Sus scrofa 456216 R-SSC-8987150 https://reactome.org/PathwayBrowser/#/R-SSC-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Sus scrofa 456216 R-SSC-8987179 https://reactome.org/PathwayBrowser/#/R-SSC-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Sus scrofa 456216 R-SSC-8987202 https://reactome.org/PathwayBrowser/#/R-SSC-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Sus scrofa 456216 R-SSC-8987255 https://reactome.org/PathwayBrowser/#/R-SSC-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Sus scrofa 456216 R-SSC-9006850 https://reactome.org/PathwayBrowser/#/R-SSC-9006850 IL21 receptor JAK phosphorylation IEA Sus scrofa 456216 R-SSC-9006870 https://reactome.org/PathwayBrowser/#/R-SSC-9006870 IL21 receptor STAT phosphorylation IEA Sus scrofa 456216 R-SSC-9007539 https://reactome.org/PathwayBrowser/#/R-SSC-9007539 CHEK1 phosphorylates E2F6 IEA Sus scrofa 456216 R-SSC-9008043 https://reactome.org/PathwayBrowser/#/R-SSC-9008043 MAPK8 phosphorylation IEA Sus scrofa 456216 R-SSC-9008412 https://reactome.org/PathwayBrowser/#/R-SSC-9008412 CDK4 phosphorylates RUNX2 IEA Sus scrofa 456216 R-SSC-9008684 https://reactome.org/PathwayBrowser/#/R-SSC-9008684 TBK1 phosphorylation IEA Sus scrofa 456216 R-SSC-9009072 https://reactome.org/PathwayBrowser/#/R-SSC-9009072 STAT3 phosphorylation IEA Sus scrofa 456216 R-SSC-9009282 https://reactome.org/PathwayBrowser/#/R-SSC-9009282 CDK1 phosphorylates RUNX2 IEA Sus scrofa 456216 R-SSC-9012319 https://reactome.org/PathwayBrowser/#/R-SSC-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Sus scrofa 456216 R-SSC-9021357 https://reactome.org/PathwayBrowser/#/R-SSC-9021357 PRKCI phosphorylates ELF3 IEA Sus scrofa 456216 R-SSC-9021609 https://reactome.org/PathwayBrowser/#/R-SSC-9021609 ESR-associated SRC autophosphorylates IEA Sus scrofa 456216 R-SSC-9021627 https://reactome.org/PathwayBrowser/#/R-SSC-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 456216 R-SSC-9022314 https://reactome.org/PathwayBrowser/#/R-SSC-9022314 HIPK2 phosphorylates MECP2 IEA Sus scrofa 456216 R-SSC-9027272 https://reactome.org/PathwayBrowser/#/R-SSC-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Sus scrofa 456216 R-SSC-9027273 https://reactome.org/PathwayBrowser/#/R-SSC-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Sus scrofa 456216 R-SSC-9033499 https://reactome.org/PathwayBrowser/#/R-SSC-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Sus scrofa 456216 R-SSC-9034714 https://reactome.org/PathwayBrowser/#/R-SSC-9034714 NTRK3 dimers trans-autophosphorylate IEA Sus scrofa 456216 R-SSC-9038161 https://reactome.org/PathwayBrowser/#/R-SSC-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Sus scrofa 456216 R-SSC-909552 https://reactome.org/PathwayBrowser/#/R-SSC-909552 Phosphorylation of STAT1 at Ser727 IEA Sus scrofa 456216 R-SSC-909718 https://reactome.org/PathwayBrowser/#/R-SSC-909718 Formation of p-STAT1 homodimer IEA Sus scrofa 456216 R-SSC-909729 https://reactome.org/PathwayBrowser/#/R-SSC-909729 Activation of JAK kinases IEA Sus scrofa 456216 R-SSC-909730 https://reactome.org/PathwayBrowser/#/R-SSC-909730 Phosphorylation of INFAR1 by TYK2 IEA Sus scrofa 456216 R-SSC-909732 https://reactome.org/PathwayBrowser/#/R-SSC-909732 Phosphorylation of STAT2 IEA Sus scrofa 456216 R-SSC-912527 https://reactome.org/PathwayBrowser/#/R-SSC-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Sus scrofa 456216 R-SSC-913996 https://reactome.org/PathwayBrowser/#/R-SSC-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Sus scrofa 456216 R-SSC-917693 https://reactome.org/PathwayBrowser/#/R-SSC-917693 ESCRT Disassembly IEA Sus scrofa 456216 R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa 456216 R-SSC-917979 https://reactome.org/PathwayBrowser/#/R-SSC-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa 456216 R-SSC-934559 https://reactome.org/PathwayBrowser/#/R-SSC-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Sus scrofa 456216 R-SSC-936802 https://reactome.org/PathwayBrowser/#/R-SSC-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Sus scrofa 456216 R-SSC-936883 https://reactome.org/PathwayBrowser/#/R-SSC-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Sus scrofa 456216 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 456216 R-SSC-936951 https://reactome.org/PathwayBrowser/#/R-SSC-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Sus scrofa 456216 R-SSC-936991 https://reactome.org/PathwayBrowser/#/R-SSC-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Sus scrofa 456216 R-SSC-937034 https://reactome.org/PathwayBrowser/#/R-SSC-937034 IRAK1 phosphorylates Pellino IEA Sus scrofa 456216 R-SSC-937311 https://reactome.org/PathwayBrowser/#/R-SSC-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Sus scrofa 456216 R-SSC-939763 https://reactome.org/PathwayBrowser/#/R-SSC-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Sus scrofa 456216 R-SSC-947591 https://reactome.org/PathwayBrowser/#/R-SSC-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Sus scrofa 456216 R-SSC-9603420 https://reactome.org/PathwayBrowser/#/R-SSC-9603420 Activated NTRK3 promotes SRC autophosphorylation IEA Sus scrofa 456216 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 456216 R-SSC-9606884 https://reactome.org/PathwayBrowser/#/R-SSC-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Sus scrofa 456216 R-SSC-9610153 https://reactome.org/PathwayBrowser/#/R-SSC-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Sus scrofa 456216 R-SSC-9610156 https://reactome.org/PathwayBrowser/#/R-SSC-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Sus scrofa 456216 R-SSC-9610163 https://reactome.org/PathwayBrowser/#/R-SSC-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Sus scrofa 456216 R-SSC-9612501 https://reactome.org/PathwayBrowser/#/R-SSC-9612501 SGK phosphorylates CREB1 IEA Sus scrofa 456216 R-SSC-9612509 https://reactome.org/PathwayBrowser/#/R-SSC-9612509 SGK phosphorylates SRF IEA Sus scrofa 456216 R-SSC-9619355 https://reactome.org/PathwayBrowser/#/R-SSC-9619355 CaMKK autophosphorylates in the cytosol IEA Sus scrofa 456216 R-SSC-9624800 https://reactome.org/PathwayBrowser/#/R-SSC-9624800 CDK1 phosphorylates LBR IEA Sus scrofa 456216 R-SSC-9626817 https://reactome.org/PathwayBrowser/#/R-SSC-9626817 PKC phosphorylates NCF1 IEA Sus scrofa 456216 R-SSC-9626832 https://reactome.org/PathwayBrowser/#/R-SSC-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Sus scrofa 456216 R-SSC-9626880 https://reactome.org/PathwayBrowser/#/R-SSC-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Sus scrofa 456216 R-SSC-9627089 https://reactome.org/PathwayBrowser/#/R-SSC-9627089 CASP9 is phosphorylated at T412 IEA Sus scrofa 456216 R-SSC-9632858 https://reactome.org/PathwayBrowser/#/R-SSC-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Sus scrofa 456216 R-SSC-9632868 https://reactome.org/PathwayBrowser/#/R-SSC-9632868 CDKN1B is phosphorylated in response to estrogen IEA Sus scrofa 456216 R-SSC-9634702 https://reactome.org/PathwayBrowser/#/R-SSC-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Sus scrofa 456216 R-SSC-9645442 https://reactome.org/PathwayBrowser/#/R-SSC-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Sus scrofa 456216 R-SSC-9645535 https://reactome.org/PathwayBrowser/#/R-SSC-9645535 ALPK1 phosphorylates TIFA IEA Sus scrofa 456216 R-SSC-9648089 https://reactome.org/PathwayBrowser/#/R-SSC-9648089 NEK6 and NEK7 phosphorylate EML4 IEA Sus scrofa 456216 R-SSC-964958 https://reactome.org/PathwayBrowser/#/R-SSC-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Sus scrofa 456216 R-SSC-964962 https://reactome.org/PathwayBrowser/#/R-SSC-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Sus scrofa 456216 R-SSC-964970 https://reactome.org/PathwayBrowser/#/R-SSC-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Sus scrofa 456216 R-SSC-9650858 https://reactome.org/PathwayBrowser/#/R-SSC-9650858 Meglitinides bind ABCC8 IEA Sus scrofa 456216 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 456216 R-SSC-9653503 https://reactome.org/PathwayBrowser/#/R-SSC-9653503 KRAS4B is phosphorylated on serine 181 IEA Sus scrofa 456216 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 456216 R-SSC-9661417 https://reactome.org/PathwayBrowser/#/R-SSC-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa 456216 R-SSC-9684118 https://reactome.org/PathwayBrowser/#/R-SSC-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa 456216 R-SSC-9686521 https://reactome.org/PathwayBrowser/#/R-SSC-9686521 CDK2:CCNA phosphorylates TERF2 IEA Sus scrofa 456216 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 456216 R-SSC-9699578 https://reactome.org/PathwayBrowser/#/R-SSC-9699578 Active FLT3 phosphorylates CDKN1B IEA Sus scrofa 456216 R-SSC-9700168 https://reactome.org/PathwayBrowser/#/R-SSC-9700168 Active ALK phosphorylates IRS1 IEA Sus scrofa 456216 R-SSC-9700171 https://reactome.org/PathwayBrowser/#/R-SSC-9700171 Active ALK phosphorylates PLCG1 IEA Sus scrofa 456216 R-SSC-9700175 https://reactome.org/PathwayBrowser/#/R-SSC-9700175 Active ALK phosphorylates SHC1 IEA Sus scrofa 456216 R-SSC-9701488 https://reactome.org/PathwayBrowser/#/R-SSC-9701488 Active ALK phosphorylates JAK3 IEA Sus scrofa 456216 R-SSC-9706344 https://reactome.org/PathwayBrowser/#/R-SSC-9706344 FLT3 phosphorylates GRB10 IEA Sus scrofa 456216 R-SSC-9706350 https://reactome.org/PathwayBrowser/#/R-SSC-9706350 FLT3 phosphorylates CBL IEA Sus scrofa 456216 R-SSC-9727198 https://reactome.org/PathwayBrowser/#/R-SSC-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Sus scrofa 456216 R-SSC-9731111 https://reactome.org/PathwayBrowser/#/R-SSC-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Sus scrofa 456216 R-SSC-9732738 https://reactome.org/PathwayBrowser/#/R-SSC-9732738 JAK1-mediated phosphorylation of RAF1 IEA Sus scrofa 456216 R-SSC-9732753 https://reactome.org/PathwayBrowser/#/R-SSC-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Sus scrofa 456216 R-SSC-9734547 https://reactome.org/PathwayBrowser/#/R-SSC-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Sus scrofa 456216 R-SSC-9734687 https://reactome.org/PathwayBrowser/#/R-SSC-9734687 ORC6 is phosphorylated on T195 IEA Sus scrofa 456216 R-SSC-9748949 https://reactome.org/PathwayBrowser/#/R-SSC-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Sus scrofa 456216 R-SSC-9748963 https://reactome.org/PathwayBrowser/#/R-SSC-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Sus scrofa 456216 R-SSC-9748969 https://reactome.org/PathwayBrowser/#/R-SSC-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Sus scrofa 456216 R-SSC-9748999 https://reactome.org/PathwayBrowser/#/R-SSC-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Sus scrofa 456216 R-SSC-9750546 https://reactome.org/PathwayBrowser/#/R-SSC-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-9750656 https://reactome.org/PathwayBrowser/#/R-SSC-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Sus scrofa 456216 R-SSC-975103 https://reactome.org/PathwayBrowser/#/R-SSC-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Sus scrofa 456216 R-SSC-975139 https://reactome.org/PathwayBrowser/#/R-SSC-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Sus scrofa 456216 R-SSC-9753278 https://reactome.org/PathwayBrowser/#/R-SSC-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 456216 R-SSC-9753283 https://reactome.org/PathwayBrowser/#/R-SSC-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 456216 R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 456216 R-SSC-9754974 https://reactome.org/PathwayBrowser/#/R-SSC-9754974 ADK phosphorylates RBV IEA Sus scrofa 456216 R-SSC-9755013 https://reactome.org/PathwayBrowser/#/R-SSC-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Sus scrofa 456216 R-SSC-9759206 https://reactome.org/PathwayBrowser/#/R-SSC-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Sus scrofa 456216 R-SSC-9759454 https://reactome.org/PathwayBrowser/#/R-SSC-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Sus scrofa 456216 R-SSC-9759461 https://reactome.org/PathwayBrowser/#/R-SSC-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Sus scrofa 456216 R-SSC-9760094 https://reactome.org/PathwayBrowser/#/R-SSC-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Sus scrofa 456216 R-SSC-9762094 https://reactome.org/PathwayBrowser/#/R-SSC-9762094 GSK3B phosphorylates p-NFE2L2 IEA Sus scrofa 456216 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa 456216 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa 456216 R-SSC-9773803 https://reactome.org/PathwayBrowser/#/R-SSC-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Sus scrofa 456216 R-SSC-9794120 https://reactome.org/PathwayBrowser/#/R-SSC-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Sus scrofa 456216 R-SSC-9794572 https://reactome.org/PathwayBrowser/#/R-SSC-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Sus scrofa 456216 R-SSC-9796053 https://reactome.org/PathwayBrowser/#/R-SSC-9796053 PRKCI phosphorylates NFE2L2 IEA Sus scrofa 456216 R-SSC-9796067 https://reactome.org/PathwayBrowser/#/R-SSC-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Sus scrofa 456216 R-SSC-9815501 https://reactome.org/PathwayBrowser/#/R-SSC-9815501 MAPKAPK2 phosphorylates RIPK1 at S320 IEA Sus scrofa 456216 R-SSC-9817397 https://reactome.org/PathwayBrowser/#/R-SSC-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Sus scrofa 456216 R-SSC-9818789 https://reactome.org/PathwayBrowser/#/R-SSC-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Sus scrofa 456216 R-SSC-9819106 https://reactome.org/PathwayBrowser/#/R-SSC-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Sus scrofa 456216 R-SSC-9823906 https://reactome.org/PathwayBrowser/#/R-SSC-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Sus scrofa 456216 R-SSC-9824882 https://reactome.org/PathwayBrowser/#/R-SSC-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Sus scrofa 456216 R-SSC-9824977 https://reactome.org/PathwayBrowser/#/R-SSC-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Sus scrofa 456216 R-SSC-9824994 https://reactome.org/PathwayBrowser/#/R-SSC-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Sus scrofa 456216 R-SSC-9824995 https://reactome.org/PathwayBrowser/#/R-SSC-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Sus scrofa 456216 R-SSC-9824999 https://reactome.org/PathwayBrowser/#/R-SSC-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Sus scrofa 456216 R-SSC-9825759 https://reactome.org/PathwayBrowser/#/R-SSC-9825759 MAPK-dependent phosphorylation of KARS IEA Sus scrofa 456216 R-SSC-982810 https://reactome.org/PathwayBrowser/#/R-SSC-982810 JAK2 phosphorylation IEA Sus scrofa 456216 R-SSC-983144 https://reactome.org/PathwayBrowser/#/R-SSC-983144 Transport of Antigen peptide in to ER IEA Sus scrofa 456216 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa 456216 R-SSC-9836159 https://reactome.org/PathwayBrowser/#/R-SSC-9836159 p-PKR dimer phosphorylates DHX9 IEA Sus scrofa 456216 R-SSC-9836184 https://reactome.org/PathwayBrowser/#/R-SSC-9836184 p-PKR dimer phosphorylates CDK1 IEA Sus scrofa 456216 R-SSC-9836322 https://reactome.org/PathwayBrowser/#/R-SSC-9836322 p-PKR dimer phosphorylates MKK6 IEA Sus scrofa 456216 R-SSC-9836362 https://reactome.org/PathwayBrowser/#/R-SSC-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Sus scrofa 456216 R-SSC-9836383 https://reactome.org/PathwayBrowser/#/R-SSC-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Sus scrofa 456216 R-SSC-9836404 https://reactome.org/PathwayBrowser/#/R-SSC-9836404 p-PKR dimer phosphorylates MAPT IEA Sus scrofa 456216 R-SSC-9836435 https://reactome.org/PathwayBrowser/#/R-SSC-9836435 p-PKR dimer phosphorylates SNCA IEA Sus scrofa 456216 R-SSC-9836515 https://reactome.org/PathwayBrowser/#/R-SSC-9836515 p-PKR dimer phosphorylates PTPN2 IEA Sus scrofa 456216 R-SSC-9836617 https://reactome.org/PathwayBrowser/#/R-SSC-9836617 p-PKR dimer phosphorylates SPHK1 IEA Sus scrofa 456216 R-SSC-9836664 https://reactome.org/PathwayBrowser/#/R-SSC-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Sus scrofa 456216 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa 456216 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa 456216 R-SSC-9837333 https://reactome.org/PathwayBrowser/#/R-SSC-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Sus scrofa 456216 R-SSC-9837337 https://reactome.org/PathwayBrowser/#/R-SSC-9837337 DCAKD phosphorylates DP-CoA IEA Sus scrofa 456216 R-SSC-9838004 https://reactome.org/PathwayBrowser/#/R-SSC-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Sus scrofa 456216 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa 456216 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa 456216 R-SSC-9838321 https://reactome.org/PathwayBrowser/#/R-SSC-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Sus scrofa 456216 R-SSC-9839059 https://reactome.org/PathwayBrowser/#/R-SSC-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Sus scrofa 456216 R-SSC-9839105 https://reactome.org/PathwayBrowser/#/R-SSC-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Sus scrofa 456216 R-SSC-9839113 https://reactome.org/PathwayBrowser/#/R-SSC-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Sus scrofa 456216 R-SSC-9843721 https://reactome.org/PathwayBrowser/#/R-SSC-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Sus scrofa 456216 R-SSC-9851972 https://reactome.org/PathwayBrowser/#/R-SSC-9851972 PLK1 phosphorylates FIRRM at S43 IEA Sus scrofa 456216 R-SSC-9853369 https://reactome.org/PathwayBrowser/#/R-SSC-9853369 PLK1 phosphorylates FIRMM at S744 IEA Sus scrofa 456216 R-SSC-9861642 https://reactome.org/PathwayBrowser/#/R-SSC-9861642 NEK1 phosphorylates ME1 IEA Sus scrofa 456216 R-SSC-994137 https://reactome.org/PathwayBrowser/#/R-SSC-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Sus scrofa 456216 R-SSC-994140 https://reactome.org/PathwayBrowser/#/R-SSC-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Sus scrofa 456216 R-XLA-2520871 https://reactome.org/PathwayBrowser/#/R-XLA-2520871 Cdk1 phosphorylates condensin I TAS Xenopus laevis 456216 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 456216 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 456216 R-XTR-109415 https://reactome.org/PathwayBrowser/#/R-XTR-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Xenopus tropicalis 456216 R-XTR-109624 https://reactome.org/PathwayBrowser/#/R-XTR-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Xenopus tropicalis 456216 R-XTR-109671 https://reactome.org/PathwayBrowser/#/R-XTR-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Xenopus tropicalis 456216 R-XTR-109699 https://reactome.org/PathwayBrowser/#/R-XTR-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-109759 https://reactome.org/PathwayBrowser/#/R-XTR-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Xenopus tropicalis 456216 R-XTR-109903 https://reactome.org/PathwayBrowser/#/R-XTR-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Xenopus tropicalis 456216 R-XTR-110133 https://reactome.org/PathwayBrowser/#/R-XTR-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Xenopus tropicalis 456216 R-XTR-110137 https://reactome.org/PathwayBrowser/#/R-XTR-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Xenopus tropicalis 456216 R-XTR-110138 https://reactome.org/PathwayBrowser/#/R-XTR-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 456216 R-XTR-110144 https://reactome.org/PathwayBrowser/#/R-XTR-110144 ADP + ADP <=> AMP + ATP [AK2] IEA Xenopus tropicalis 456216 R-XTR-110145 https://reactome.org/PathwayBrowser/#/R-XTR-110145 AMP + ATP <=> ADP + ADP [AK2] IEA Xenopus tropicalis 456216 R-XTR-1112510 https://reactome.org/PathwayBrowser/#/R-XTR-1112510 IL6ST is tyrosine phosphorylated IEA Xenopus tropicalis 456216 R-XTR-1112514 https://reactome.org/PathwayBrowser/#/R-XTR-1112514 JAK activation IEA Xenopus tropicalis 456216 R-XTR-1112602 https://reactome.org/PathwayBrowser/#/R-XTR-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Xenopus tropicalis 456216 R-XTR-1112703 https://reactome.org/PathwayBrowser/#/R-XTR-1112703 PTPN11 is phosphorylated IEA Xenopus tropicalis 456216 R-XTR-1112727 https://reactome.org/PathwayBrowser/#/R-XTR-1112727 Serine phosphorylation of STATs IEA Xenopus tropicalis 456216 R-XTR-111898 https://reactome.org/PathwayBrowser/#/R-XTR-111898 Phosphorylation of cPLA2 by ERK-2 IEA Xenopus tropicalis 456216 R-XTR-111970 https://reactome.org/PathwayBrowser/#/R-XTR-111970 PKC phosphorylates GRK2 IEA Xenopus tropicalis 456216 R-XTR-112381 https://reactome.org/PathwayBrowser/#/R-XTR-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Xenopus tropicalis 456216 R-XTR-114252 https://reactome.org/PathwayBrowser/#/R-XTR-114252 Cleavage of Procaspase-3 by the apoptosome IEA Xenopus tropicalis 456216 R-XTR-114254 https://reactome.org/PathwayBrowser/#/R-XTR-114254 CYCS binds to APAF1 IEA Xenopus tropicalis 456216 R-XTR-114259 https://reactome.org/PathwayBrowser/#/R-XTR-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Xenopus tropicalis 456216 R-XTR-114261 https://reactome.org/PathwayBrowser/#/R-XTR-114261 Cleavage of Procaspase-7 by the apoptosome IEA Xenopus tropicalis 456216 R-XTR-114600 https://reactome.org/PathwayBrowser/#/R-XTR-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Xenopus tropicalis 456216 R-XTR-114683 https://reactome.org/PathwayBrowser/#/R-XTR-114683 Phosphorylation of Platelet Sec-1 IEA Xenopus tropicalis 456216 R-XTR-114684 https://reactome.org/PathwayBrowser/#/R-XTR-114684 Phosphorylation of Syntaxin-4 IEA Xenopus tropicalis 456216 R-XTR-1168635 https://reactome.org/PathwayBrowser/#/R-XTR-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Xenopus tropicalis 456216 R-XTR-1181149 https://reactome.org/PathwayBrowser/#/R-XTR-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Xenopus tropicalis 456216 R-XTR-1226094 https://reactome.org/PathwayBrowser/#/R-XTR-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Xenopus tropicalis 456216 R-XTR-1226095 https://reactome.org/PathwayBrowser/#/R-XTR-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Xenopus tropicalis 456216 R-XTR-1247935 https://reactome.org/PathwayBrowser/#/R-XTR-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Xenopus tropicalis 456216 R-XTR-1247960 https://reactome.org/PathwayBrowser/#/R-XTR-1247960 Activation of p38 MAPK IEA Xenopus tropicalis 456216 R-XTR-1250195 https://reactome.org/PathwayBrowser/#/R-XTR-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Xenopus tropicalis 456216 R-XTR-1250315 https://reactome.org/PathwayBrowser/#/R-XTR-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Xenopus tropicalis 456216 R-XTR-1250348 https://reactome.org/PathwayBrowser/#/R-XTR-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Xenopus tropicalis 456216 R-XTR-1250370 https://reactome.org/PathwayBrowser/#/R-XTR-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Xenopus tropicalis 456216 R-XTR-1306957 https://reactome.org/PathwayBrowser/#/R-XTR-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Xenopus tropicalis 456216 R-XTR-1306979 https://reactome.org/PathwayBrowser/#/R-XTR-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Xenopus tropicalis 456216 R-XTR-1307963 https://reactome.org/PathwayBrowser/#/R-XTR-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Xenopus tropicalis 456216 R-XTR-1362270 https://reactome.org/PathwayBrowser/#/R-XTR-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Xenopus tropicalis 456216 R-XTR-1369065 https://reactome.org/PathwayBrowser/#/R-XTR-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Xenopus tropicalis 456216 R-XTR-1370505 https://reactome.org/PathwayBrowser/#/R-XTR-1370505 PRLR is phosphorylated at Ser-349 IEA Xenopus tropicalis 456216 R-XTR-1433418 https://reactome.org/PathwayBrowser/#/R-XTR-1433418 Phosphorylation of JAK2 IEA Xenopus tropicalis 456216 R-XTR-1433454 https://reactome.org/PathwayBrowser/#/R-XTR-1433454 Phosphorylation of GAB2 by SFKs IEA Xenopus tropicalis 456216 R-XTR-1433488 https://reactome.org/PathwayBrowser/#/R-XTR-1433488 Phosphorylation of SHP2 by SFKs IEA Xenopus tropicalis 456216 R-XTR-1433506 https://reactome.org/PathwayBrowser/#/R-XTR-1433506 Phosphorylation of APS IEA Xenopus tropicalis 456216 R-XTR-1433514 https://reactome.org/PathwayBrowser/#/R-XTR-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Xenopus tropicalis 456216 R-XTR-1433542 https://reactome.org/PathwayBrowser/#/R-XTR-1433542 Phosphorylation and activation of VAV1 IEA Xenopus tropicalis 456216 R-XTR-1454916 https://reactome.org/PathwayBrowser/#/R-XTR-1454916 The ABCC family mediates organic anion transport IEA Xenopus tropicalis 456216 R-XTR-1454928 https://reactome.org/PathwayBrowser/#/R-XTR-1454928 ABCG4 may mediate cholesterol efflux IEA Xenopus tropicalis 456216 R-XTR-1467466 https://reactome.org/PathwayBrowser/#/R-XTR-1467466 ABCA4 mediates atRAL transport IEA Xenopus tropicalis 456216 R-XTR-1470009 https://reactome.org/PathwayBrowser/#/R-XTR-1470009 Phosphorylation of STATs IEA Xenopus tropicalis 456216 R-XTR-1472121 https://reactome.org/PathwayBrowser/#/R-XTR-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Xenopus tropicalis 456216 R-XTR-1475422 https://reactome.org/PathwayBrowser/#/R-XTR-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II IEA Xenopus tropicalis 456216 R-XTR-1483004 https://reactome.org/PathwayBrowser/#/R-XTR-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Xenopus tropicalis 456216 R-XTR-1483222 https://reactome.org/PathwayBrowser/#/R-XTR-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Xenopus tropicalis 456216 R-XTR-1497853 https://reactome.org/PathwayBrowser/#/R-XTR-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II IEA Xenopus tropicalis 456216 R-XTR-1524186 https://reactome.org/PathwayBrowser/#/R-XTR-1524186 Phosphorylation of PLCgamma by PDGFR IEA Xenopus tropicalis 456216 R-XTR-1549526 https://reactome.org/PathwayBrowser/#/R-XTR-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Xenopus tropicalis 456216 R-XTR-156673 https://reactome.org/PathwayBrowser/#/R-XTR-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Xenopus tropicalis 456216 R-XTR-156682 https://reactome.org/PathwayBrowser/#/R-XTR-156682 PLK1 phosphorylates NUDC IEA Xenopus tropicalis 456216 R-XTR-156699 https://reactome.org/PathwayBrowser/#/R-XTR-156699 Inactivation of Wee1 kinase IEA Xenopus tropicalis 456216 R-XTR-156723 https://reactome.org/PathwayBrowser/#/R-XTR-156723 Regulation of KIF20A (MKL2) by phosphorylation IEA Xenopus tropicalis 456216 R-XTR-163010 https://reactome.org/PathwayBrowser/#/R-XTR-163010 Down Regulation of Emi1 through Phosphorylation of Emi1 IEA Xenopus tropicalis 456216 R-XTR-163215 https://reactome.org/PathwayBrowser/#/R-XTR-163215 SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane IEA Xenopus tropicalis 456216 R-XTR-1632857 https://reactome.org/PathwayBrowser/#/R-XTR-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Xenopus tropicalis 456216 R-XTR-1638803 https://reactome.org/PathwayBrowser/#/R-XTR-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Xenopus tropicalis 456216 R-XTR-1638845 https://reactome.org/PathwayBrowser/#/R-XTR-1638845 CERK phosphorylates CERA to form C1P IEA Xenopus tropicalis 456216 R-XTR-1675773 https://reactome.org/PathwayBrowser/#/R-XTR-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Xenopus tropicalis 456216 R-XTR-1675776 https://reactome.org/PathwayBrowser/#/R-XTR-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Xenopus tropicalis 456216 R-XTR-1675780 https://reactome.org/PathwayBrowser/#/R-XTR-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Xenopus tropicalis 456216 R-XTR-1675813 https://reactome.org/PathwayBrowser/#/R-XTR-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Xenopus tropicalis 456216 R-XTR-1675883 https://reactome.org/PathwayBrowser/#/R-XTR-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Xenopus tropicalis 456216 R-XTR-1675928 https://reactome.org/PathwayBrowser/#/R-XTR-1675928 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane IEA Xenopus tropicalis 456216 R-XTR-1675939 https://reactome.org/PathwayBrowser/#/R-XTR-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Xenopus tropicalis 456216 R-XTR-1675961 https://reactome.org/PathwayBrowser/#/R-XTR-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Xenopus tropicalis 456216 R-XTR-1675974 https://reactome.org/PathwayBrowser/#/R-XTR-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Xenopus tropicalis 456216 R-XTR-1676024 https://reactome.org/PathwayBrowser/#/R-XTR-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Xenopus tropicalis 456216 R-XTR-1676048 https://reactome.org/PathwayBrowser/#/R-XTR-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Xenopus tropicalis 456216 R-XTR-1676082 https://reactome.org/PathwayBrowser/#/R-XTR-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Xenopus tropicalis 456216 R-XTR-1676109 https://reactome.org/PathwayBrowser/#/R-XTR-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Xenopus tropicalis 456216 R-XTR-1676145 https://reactome.org/PathwayBrowser/#/R-XTR-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Xenopus tropicalis 456216 R-XTR-1676185 https://reactome.org/PathwayBrowser/#/R-XTR-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Xenopus tropicalis 456216 R-XTR-1676206 https://reactome.org/PathwayBrowser/#/R-XTR-1676206 PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane IEA Xenopus tropicalis 456216 R-XTR-168053 https://reactome.org/PathwayBrowser/#/R-XTR-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Xenopus tropicalis 456216 R-XTR-169905 https://reactome.org/PathwayBrowser/#/R-XTR-169905 ARMS is phosphorylated by active TrkA receptor IEA Xenopus tropicalis 456216 R-XTR-170026 https://reactome.org/PathwayBrowser/#/R-XTR-170026 Protons are translocated from the intermembrane space to the matrix IEA Xenopus tropicalis 456216 R-XTR-170070 https://reactome.org/PathwayBrowser/#/R-XTR-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Xenopus tropicalis 456216 R-XTR-170076 https://reactome.org/PathwayBrowser/#/R-XTR-170076 CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes IEA Xenopus tropicalis 456216 R-XTR-170087 https://reactome.org/PathwayBrowser/#/R-XTR-170087 CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes IEA Xenopus tropicalis 456216 R-XTR-170126 https://reactome.org/PathwayBrowser/#/R-XTR-170126 Phosphorylation of Cyclin B1 in the CRS domain IEA Xenopus tropicalis 456216 R-XTR-170977 https://reactome.org/PathwayBrowser/#/R-XTR-170977 FRS2 is phosphorylated by active TrkA receptor IEA Xenopus tropicalis 456216 R-XTR-174079 https://reactome.org/PathwayBrowser/#/R-XTR-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Xenopus tropicalis 456216 R-XTR-174122 https://reactome.org/PathwayBrowser/#/R-XTR-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Xenopus tropicalis 456216 R-XTR-174164 https://reactome.org/PathwayBrowser/#/R-XTR-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Xenopus tropicalis 456216 R-XTR-174174 https://reactome.org/PathwayBrowser/#/R-XTR-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Xenopus tropicalis 456216 R-XTR-174251 https://reactome.org/PathwayBrowser/#/R-XTR-174251 Phosphorylation of Cdh1 by Cyclin B1:Cdc2 IEA Xenopus tropicalis 456216 R-XTR-174367 https://reactome.org/PathwayBrowser/#/R-XTR-174367 GCL ligates L-Glu to L-Cys IEA Xenopus tropicalis 456216 R-XTR-174389 https://reactome.org/PathwayBrowser/#/R-XTR-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Xenopus tropicalis 456216 R-XTR-174439 https://reactome.org/PathwayBrowser/#/R-XTR-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Xenopus tropicalis 456216 R-XTR-177275 https://reactome.org/PathwayBrowser/#/R-XTR-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Xenopus tropicalis 456216 R-XTR-177284 https://reactome.org/PathwayBrowser/#/R-XTR-177284 PKA phosphorylates PDE4B IEA Xenopus tropicalis 456216 R-XTR-177930 https://reactome.org/PathwayBrowser/#/R-XTR-177930 GAB1 phosphorylation by EGFR kinase IEA Xenopus tropicalis 456216 R-XTR-177933 https://reactome.org/PathwayBrowser/#/R-XTR-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Xenopus tropicalis 456216 R-XTR-177934 https://reactome.org/PathwayBrowser/#/R-XTR-177934 EGFR autophosphorylation IEA Xenopus tropicalis 456216 R-XTR-177939 https://reactome.org/PathwayBrowser/#/R-XTR-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Xenopus tropicalis 456216 R-XTR-183058 https://reactome.org/PathwayBrowser/#/R-XTR-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Xenopus tropicalis 456216 R-XTR-1855157 https://reactome.org/PathwayBrowser/#/R-XTR-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 456216 R-XTR-1855158 https://reactome.org/PathwayBrowser/#/R-XTR-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855162 https://reactome.org/PathwayBrowser/#/R-XTR-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855169 https://reactome.org/PathwayBrowser/#/R-XTR-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855172 https://reactome.org/PathwayBrowser/#/R-XTR-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855176 https://reactome.org/PathwayBrowser/#/R-XTR-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Xenopus tropicalis 456216 R-XTR-1855179 https://reactome.org/PathwayBrowser/#/R-XTR-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855181 https://reactome.org/PathwayBrowser/#/R-XTR-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 456216 R-XTR-1855182 https://reactome.org/PathwayBrowser/#/R-XTR-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855185 https://reactome.org/PathwayBrowser/#/R-XTR-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 456216 R-XTR-1855193 https://reactome.org/PathwayBrowser/#/R-XTR-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855194 https://reactome.org/PathwayBrowser/#/R-XTR-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855197 https://reactome.org/PathwayBrowser/#/R-XTR-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855206 https://reactome.org/PathwayBrowser/#/R-XTR-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 456216 R-XTR-1855207 https://reactome.org/PathwayBrowser/#/R-XTR-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 456216 R-XTR-1855216 https://reactome.org/PathwayBrowser/#/R-XTR-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855223 https://reactome.org/PathwayBrowser/#/R-XTR-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855224 https://reactome.org/PathwayBrowser/#/R-XTR-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 456216 R-XTR-1855227 https://reactome.org/PathwayBrowser/#/R-XTR-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 456216 R-XTR-1855228 https://reactome.org/PathwayBrowser/#/R-XTR-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 456216 R-XTR-1855230 https://reactome.org/PathwayBrowser/#/R-XTR-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 456216 R-XTR-1855233 https://reactome.org/PathwayBrowser/#/R-XTR-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Xenopus tropicalis 456216 R-XTR-186786 https://reactome.org/PathwayBrowser/#/R-XTR-186786 Autophosphorylation of PDGF beta receptors IEA Xenopus tropicalis 456216 R-XTR-186800 https://reactome.org/PathwayBrowser/#/R-XTR-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-187520 https://reactome.org/PathwayBrowser/#/R-XTR-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Xenopus tropicalis 456216 R-XTR-187916 https://reactome.org/PathwayBrowser/#/R-XTR-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Xenopus tropicalis 456216 R-XTR-187948 https://reactome.org/PathwayBrowser/#/R-XTR-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Xenopus tropicalis 456216 R-XTR-187949 https://reactome.org/PathwayBrowser/#/R-XTR-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Xenopus tropicalis 456216 R-XTR-187959 https://reactome.org/PathwayBrowser/#/R-XTR-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Xenopus tropicalis 456216 R-XTR-188350 https://reactome.org/PathwayBrowser/#/R-XTR-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Xenopus tropicalis 456216 R-XTR-188390 https://reactome.org/PathwayBrowser/#/R-XTR-188390 Cyclin E:CDK2-mediated phosphorylation of RB1 IEA Xenopus tropicalis 456216 R-XTR-190326 https://reactome.org/PathwayBrowser/#/R-XTR-190326 Autocatalytic phosphorylation of FGFR4 IEA Xenopus tropicalis 456216 R-XTR-190427 https://reactome.org/PathwayBrowser/#/R-XTR-190427 Autocatalytic phosphorylation of FGFR1b IEA Xenopus tropicalis 456216 R-XTR-190429 https://reactome.org/PathwayBrowser/#/R-XTR-190429 Autocatalytic phosphorylation of FGFR1c IEA Xenopus tropicalis 456216 R-XTR-191062 https://reactome.org/PathwayBrowser/#/R-XTR-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Xenopus tropicalis 456216 R-XTR-191414 https://reactome.org/PathwayBrowser/#/R-XTR-191414 MVD decarboxylates MVA5PP to IPPP IEA Xenopus tropicalis 456216 R-XTR-194153 https://reactome.org/PathwayBrowser/#/R-XTR-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 456216 R-XTR-196773 https://reactome.org/PathwayBrowser/#/R-XTR-196773 COASY phosphorylates DP-CoA IEA Xenopus tropicalis 456216 R-XTR-196857 https://reactome.org/PathwayBrowser/#/R-XTR-196857 PANK2 phosphorylates PanK IEA Xenopus tropicalis 456216 R-XTR-196964 https://reactome.org/PathwayBrowser/#/R-XTR-196964 RFK:Mg2+ phosphorylates RIB IEA Xenopus tropicalis 456216 R-XTR-197198 https://reactome.org/PathwayBrowser/#/R-XTR-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 456216 R-XTR-197958 https://reactome.org/PathwayBrowser/#/R-XTR-197958 FPGS-2 transforms THF to THFPG IEA Xenopus tropicalis 456216 R-XTR-198266 https://reactome.org/PathwayBrowser/#/R-XTR-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Xenopus tropicalis 456216 R-XTR-198314 https://reactome.org/PathwayBrowser/#/R-XTR-198314 DAG stimulates protein kinase C-delta IEA Xenopus tropicalis 456216 R-XTR-198746 https://reactome.org/PathwayBrowser/#/R-XTR-198746 ERK1/2/5 activate RSK1/2/3 IEA Xenopus tropicalis 456216 R-XTR-199895 https://reactome.org/PathwayBrowser/#/R-XTR-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Xenopus tropicalis 456216 R-XTR-200318 https://reactome.org/PathwayBrowser/#/R-XTR-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Xenopus tropicalis 456216 R-XTR-200326 https://reactome.org/PathwayBrowser/#/R-XTR-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Xenopus tropicalis 456216 R-XTR-200555 https://reactome.org/PathwayBrowser/#/R-XTR-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Xenopus tropicalis 456216 R-XTR-200681 https://reactome.org/PathwayBrowser/#/R-XTR-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Xenopus tropicalis 456216 R-XTR-200682 https://reactome.org/PathwayBrowser/#/R-XTR-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Xenopus tropicalis 456216 R-XTR-200711 https://reactome.org/PathwayBrowser/#/R-XTR-200711 MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG IEA Xenopus tropicalis 456216 R-XTR-201443 https://reactome.org/PathwayBrowser/#/R-XTR-201443 Type II receptor phosphorylates type I receptor IEA Xenopus tropicalis 456216 R-XTR-201476 https://reactome.org/PathwayBrowser/#/R-XTR-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Xenopus tropicalis 456216 R-XTR-201510 https://reactome.org/PathwayBrowser/#/R-XTR-201510 PI3K synthesizes PIP3 downstream of ALK IEA Xenopus tropicalis 456216 R-XTR-202248 https://reactome.org/PathwayBrowser/#/R-XTR-202248 Phosphorylation of PLC-gamma1 IEA Xenopus tropicalis 456216 R-XTR-2028284 https://reactome.org/PathwayBrowser/#/R-XTR-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Xenopus tropicalis 456216 R-XTR-2028555 https://reactome.org/PathwayBrowser/#/R-XTR-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Xenopus tropicalis 456216 R-XTR-2028589 https://reactome.org/PathwayBrowser/#/R-XTR-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Xenopus tropicalis 456216 R-XTR-2028591 https://reactome.org/PathwayBrowser/#/R-XTR-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Xenopus tropicalis 456216 R-XTR-2028598 https://reactome.org/PathwayBrowser/#/R-XTR-2028598 Phosphorylation of YAP by LATS1 IEA Xenopus tropicalis 456216 R-XTR-2028629 https://reactome.org/PathwayBrowser/#/R-XTR-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Xenopus tropicalis 456216 R-XTR-2028635 https://reactome.org/PathwayBrowser/#/R-XTR-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Xenopus tropicalis 456216 R-XTR-2028670 https://reactome.org/PathwayBrowser/#/R-XTR-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Xenopus tropicalis 456216 R-XTR-2028673 https://reactome.org/PathwayBrowser/#/R-XTR-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Xenopus tropicalis 456216 R-XTR-2028675 https://reactome.org/PathwayBrowser/#/R-XTR-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Xenopus tropicalis 456216 R-XTR-2028679 https://reactome.org/PathwayBrowser/#/R-XTR-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Xenopus tropicalis 456216 R-XTR-2029454 https://reactome.org/PathwayBrowser/#/R-XTR-2029454 Autophosphorylation of PAK1 IEA Xenopus tropicalis 456216 R-XTR-2029460 https://reactome.org/PathwayBrowser/#/R-XTR-2029460 PAK1 phosphorylates LIMK1 IEA Xenopus tropicalis 456216 R-XTR-2029469 https://reactome.org/PathwayBrowser/#/R-XTR-2029469 p-ERK phosphorylates WAVEs and ABI IEA Xenopus tropicalis 456216 R-XTR-2029473 https://reactome.org/PathwayBrowser/#/R-XTR-2029473 Branching and elongation of mother and daughter filaments IEA Xenopus tropicalis 456216 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 456216 R-XTR-2046087 https://reactome.org/PathwayBrowser/#/R-XTR-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Xenopus tropicalis 456216 R-XTR-2046093 https://reactome.org/PathwayBrowser/#/R-XTR-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Xenopus tropicalis 456216 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 456216 R-XTR-2060328 https://reactome.org/PathwayBrowser/#/R-XTR-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Xenopus tropicalis 456216 R-XTR-212710 https://reactome.org/PathwayBrowser/#/R-XTR-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Xenopus tropicalis 456216 R-XTR-2130194 https://reactome.org/PathwayBrowser/#/R-XTR-2130194 ABL phosphorylates WAVEs IEA Xenopus tropicalis 456216 R-XTR-2197690 https://reactome.org/PathwayBrowser/#/R-XTR-2197690 Detachment of WASP/WAVE IEA Xenopus tropicalis 456216 R-XTR-2214351 https://reactome.org/PathwayBrowser/#/R-XTR-2214351 PLK1 phosphorylates GORASP1 IEA Xenopus tropicalis 456216 R-XTR-2267372 https://reactome.org/PathwayBrowser/#/R-XTR-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Xenopus tropicalis 456216 R-XTR-2316434 https://reactome.org/PathwayBrowser/#/R-XTR-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-2404193 https://reactome.org/PathwayBrowser/#/R-XTR-2404193 IGF1R phosphorylates SHC1 IEA Xenopus tropicalis 456216 R-XTR-2404199 https://reactome.org/PathwayBrowser/#/R-XTR-2404199 IGF1,2:IGF1R autophosphorylates IEA Xenopus tropicalis 456216 R-XTR-2422927 https://reactome.org/PathwayBrowser/#/R-XTR-2422927 MAPK3-3 or MAPK1 phosphorylate GORASP2 IEA Xenopus tropicalis 456216 R-XTR-2424487 https://reactome.org/PathwayBrowser/#/R-XTR-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Xenopus tropicalis 456216 R-XTR-2428926 https://reactome.org/PathwayBrowser/#/R-XTR-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Xenopus tropicalis 456216 R-XTR-2466068 https://reactome.org/PathwayBrowser/#/R-XTR-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Xenopus tropicalis 456216 R-XTR-2468287 https://reactome.org/PathwayBrowser/#/R-XTR-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Xenopus tropicalis 456216 R-XTR-2468293 https://reactome.org/PathwayBrowser/#/R-XTR-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Xenopus tropicalis 456216 R-XTR-2562526 https://reactome.org/PathwayBrowser/#/R-XTR-2562526 PLK1 phosphorylates OPTN IEA Xenopus tropicalis 456216 R-XTR-2574840 https://reactome.org/PathwayBrowser/#/R-XTR-2574840 AJUBA facilitates AURKA autophosphorylation IEA Xenopus tropicalis 456216 R-XTR-265682 https://reactome.org/PathwayBrowser/#/R-XTR-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Xenopus tropicalis 456216 R-XTR-266082 https://reactome.org/PathwayBrowser/#/R-XTR-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Xenopus tropicalis 456216 R-XTR-2730841 https://reactome.org/PathwayBrowser/#/R-XTR-2730841 Phosphorylation and activation of VAV IEA Xenopus tropicalis 456216 R-XTR-2730856 https://reactome.org/PathwayBrowser/#/R-XTR-2730856 Autophosphorylation of PAK IEA Xenopus tropicalis 456216 R-XTR-2730858 https://reactome.org/PathwayBrowser/#/R-XTR-2730858 Autophosphorylation of BTK/ITK IEA Xenopus tropicalis 456216 R-XTR-2730862 https://reactome.org/PathwayBrowser/#/R-XTR-2730862 Autophosphorylation of LYN kinase IEA Xenopus tropicalis 456216 R-XTR-2730870 https://reactome.org/PathwayBrowser/#/R-XTR-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Xenopus tropicalis 456216 R-XTR-2730896 https://reactome.org/PathwayBrowser/#/R-XTR-2730896 Phosphorylation of MEK4 by MEKK1 IEA Xenopus tropicalis 456216 R-XTR-2990882 https://reactome.org/PathwayBrowser/#/R-XTR-2990882 CDK1 phosphorylates NUP98 IEA Xenopus tropicalis 456216 R-XTR-3000310 https://reactome.org/PathwayBrowser/#/R-XTR-3000310 AURKA phosphorylates PLK1 IEA Xenopus tropicalis 456216 R-XTR-3000327 https://reactome.org/PathwayBrowser/#/R-XTR-3000327 PLK1 phosphorylates BORA IEA Xenopus tropicalis 456216 R-XTR-3095901 https://reactome.org/PathwayBrowser/#/R-XTR-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Xenopus tropicalis 456216 R-XTR-3132737 https://reactome.org/PathwayBrowser/#/R-XTR-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Xenopus tropicalis 456216 R-XTR-3249371 https://reactome.org/PathwayBrowser/#/R-XTR-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Xenopus tropicalis 456216 R-XTR-3249379 https://reactome.org/PathwayBrowser/#/R-XTR-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Xenopus tropicalis 456216 R-XTR-3249390 https://reactome.org/PathwayBrowser/#/R-XTR-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Xenopus tropicalis 456216 R-XTR-3371422 https://reactome.org/PathwayBrowser/#/R-XTR-3371422 ATP hydrolysis by HSP70 IEA Xenopus tropicalis 456216 R-XTR-3371503 https://reactome.org/PathwayBrowser/#/R-XTR-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Xenopus tropicalis 456216 R-XTR-374701 https://reactome.org/PathwayBrowser/#/R-XTR-374701 Phosphorylation of DCC by Fyn IEA Xenopus tropicalis 456216 R-XTR-3772435 https://reactome.org/PathwayBrowser/#/R-XTR-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Xenopus tropicalis 456216 R-XTR-3788705 https://reactome.org/PathwayBrowser/#/R-XTR-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Xenopus tropicalis 456216 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 456216 R-XTR-380272 https://reactome.org/PathwayBrowser/#/R-XTR-380272 Plk1-mediated phosphorylation of Nlp IEA Xenopus tropicalis 456216 R-XTR-380278 https://reactome.org/PathwayBrowser/#/R-XTR-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Xenopus tropicalis 456216 R-XTR-381091 https://reactome.org/PathwayBrowser/#/R-XTR-381091 IRE1 dimer autophosphorylates IEA Xenopus tropicalis 456216 R-XTR-381111 https://reactome.org/PathwayBrowser/#/R-XTR-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Xenopus tropicalis 456216 R-XTR-382560 https://reactome.org/PathwayBrowser/#/R-XTR-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Xenopus tropicalis 456216 R-XTR-382575 https://reactome.org/PathwayBrowser/#/R-XTR-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Xenopus tropicalis 456216 R-XTR-383190 https://reactome.org/PathwayBrowser/#/R-XTR-383190 HCO3- transport through ion channel IEA Xenopus tropicalis 456216 R-XTR-388831 https://reactome.org/PathwayBrowser/#/R-XTR-388831 Phosphorylation of CD28 IEA Xenopus tropicalis 456216 R-XTR-389086 https://reactome.org/PathwayBrowser/#/R-XTR-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Xenopus tropicalis 456216 R-XTR-389158 https://reactome.org/PathwayBrowser/#/R-XTR-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-389354 https://reactome.org/PathwayBrowser/#/R-XTR-389354 Activation of Vav1 IEA Xenopus tropicalis 456216 R-XTR-392187 https://reactome.org/PathwayBrowser/#/R-XTR-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Xenopus tropicalis 456216 R-XTR-392195 https://reactome.org/PathwayBrowser/#/R-XTR-392195 Gi activation by P2Y purinoceptor 12 IEA Xenopus tropicalis 456216 R-XTR-392202 https://reactome.org/PathwayBrowser/#/R-XTR-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Xenopus tropicalis 456216 R-XTR-392300 https://reactome.org/PathwayBrowser/#/R-XTR-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-392530 https://reactome.org/PathwayBrowser/#/R-XTR-392530 p-S400-Cot phosphorylates NIK IEA Xenopus tropicalis 456216 R-XTR-3928578 https://reactome.org/PathwayBrowser/#/R-XTR-3928578 EPH receptors autophosphorylate IEA Xenopus tropicalis 456216 R-XTR-3928604 https://reactome.org/PathwayBrowser/#/R-XTR-3928604 SFKs phosphorylate VAV2,3 IEA Xenopus tropicalis 456216 R-XTR-3928620 https://reactome.org/PathwayBrowser/#/R-XTR-3928620 PAK1 autophosphorylates IEA Xenopus tropicalis 456216 R-XTR-3928625 https://reactome.org/PathwayBrowser/#/R-XTR-3928625 PAKs autophosphorylate IEA Xenopus tropicalis 456216 R-XTR-3928627 https://reactome.org/PathwayBrowser/#/R-XTR-3928627 EPHB phosphorylates TIAM1 IEA Xenopus tropicalis 456216 R-XTR-3928640 https://reactome.org/PathwayBrowser/#/R-XTR-3928640 PAKs phosphorylate MLC IEA Xenopus tropicalis 456216 R-XTR-399939 https://reactome.org/PathwayBrowser/#/R-XTR-399939 Autophosphorylation of PAK IEA Xenopus tropicalis 456216 R-XTR-399944 https://reactome.org/PathwayBrowser/#/R-XTR-399944 Phosphorylation of CRMPs by Cdk5 IEA Xenopus tropicalis 456216 R-XTR-399947 https://reactome.org/PathwayBrowser/#/R-XTR-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Xenopus tropicalis 456216 R-XTR-399952 https://reactome.org/PathwayBrowser/#/R-XTR-399952 Phosphorylation of LIMK-1 by PAK IEA Xenopus tropicalis 456216 R-XTR-4085028 https://reactome.org/PathwayBrowser/#/R-XTR-4085028 GNE phosphorylates ManNAc to ManNAc-6-P IEA Xenopus tropicalis 456216 R-XTR-4086410 https://reactome.org/PathwayBrowser/#/R-XTR-4086410 CDK1 phosphorylates BORA IEA Xenopus tropicalis 456216 R-XTR-4088024 https://reactome.org/PathwayBrowser/#/R-XTR-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Xenopus tropicalis 456216 R-XTR-4088134 https://reactome.org/PathwayBrowser/#/R-XTR-4088134 PLK1 phosphorylates FOXM1 IEA Xenopus tropicalis 456216 R-XTR-4093332 https://reactome.org/PathwayBrowser/#/R-XTR-4093332 p-EPHB phosphorylates SDC2 IEA Xenopus tropicalis 456216 R-XTR-417829 https://reactome.org/PathwayBrowser/#/R-XTR-417829 P2RY12 binds ADP IEA Xenopus tropicalis 456216 R-XTR-417843 https://reactome.org/PathwayBrowser/#/R-XTR-417843 P2Y13 binds ADP IEA Xenopus tropicalis 456216 R-XTR-417908 https://reactome.org/PathwayBrowser/#/R-XTR-417908 P2RY1 binds ADP IEA Xenopus tropicalis 456216 R-XTR-418576 https://reactome.org/PathwayBrowser/#/R-XTR-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Xenopus tropicalis 456216 R-XTR-419644 https://reactome.org/PathwayBrowser/#/R-XTR-419644 Transphosphorylation of pLIMK1 IEA Xenopus tropicalis 456216 R-XTR-419646 https://reactome.org/PathwayBrowser/#/R-XTR-419646 SEMA4D interacts with Plexin-B1:Met IEA Xenopus tropicalis 456216 R-XTR-426240 https://reactome.org/PathwayBrowser/#/R-XTR-426240 DAG kinase produces phosphatidic acid from DAG IEA Xenopus tropicalis 456216 R-XTR-428941 https://reactome.org/PathwayBrowser/#/R-XTR-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Xenopus tropicalis 456216 R-XTR-428961 https://reactome.org/PathwayBrowser/#/R-XTR-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Xenopus tropicalis 456216 R-XTR-429449 https://reactome.org/PathwayBrowser/#/R-XTR-429449 Syk activation leads to SLP-76 activation IEA Xenopus tropicalis 456216 R-XTR-432148 https://reactome.org/PathwayBrowser/#/R-XTR-432148 Fgr may phosphorylate p38 MAPK IEA Xenopus tropicalis 456216 R-XTR-432232 https://reactome.org/PathwayBrowser/#/R-XTR-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Xenopus tropicalis 456216 R-XTR-437162 https://reactome.org/PathwayBrowser/#/R-XTR-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-4411402 https://reactome.org/PathwayBrowser/#/R-XTR-4411402 Activation of NLK IEA Xenopus tropicalis 456216 R-XTR-4420117 https://reactome.org/PathwayBrowser/#/R-XTR-4420117 VEGFR2 autophosphorylates IEA Xenopus tropicalis 456216 R-XTR-442724 https://reactome.org/PathwayBrowser/#/R-XTR-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Xenopus tropicalis 456216 R-XTR-445072 https://reactome.org/PathwayBrowser/#/R-XTR-445072 Interaction of PAK1 with Rac1-GTP IEA Xenopus tropicalis 456216 R-XTR-445079 https://reactome.org/PathwayBrowser/#/R-XTR-445079 Phosphorylation of L1 by ERK IEA Xenopus tropicalis 456216 R-XTR-446634 https://reactome.org/PathwayBrowser/#/R-XTR-446634 IRAK4 is activated by autophosphorylation IEA Xenopus tropicalis 456216 R-XTR-448955 https://reactome.org/PathwayBrowser/#/R-XTR-448955 Phosphorylation of MEF2 proteins by p38 IEA Xenopus tropicalis 456216 R-XTR-450325 https://reactome.org/PathwayBrowser/#/R-XTR-450325 c-FOS activation by phospho ERK1/2 IEA Xenopus tropicalis 456216 R-XTR-450337 https://reactome.org/PathwayBrowser/#/R-XTR-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Xenopus tropicalis 456216 R-XTR-450346 https://reactome.org/PathwayBrowser/#/R-XTR-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Xenopus tropicalis 456216 R-XTR-450533 https://reactome.org/PathwayBrowser/#/R-XTR-450533 PKCdelta phosphorylates HuR IEA Xenopus tropicalis 456216 R-XTR-453200 https://reactome.org/PathwayBrowser/#/R-XTR-453200 SYK autophosphorylates IEA Xenopus tropicalis 456216 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 456216 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 456216 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 456216 R-XTR-508040 https://reactome.org/PathwayBrowser/#/R-XTR-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Xenopus tropicalis 456216 R-XTR-508308 https://reactome.org/PathwayBrowser/#/R-XTR-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Xenopus tropicalis 456216 R-XTR-5138432 https://reactome.org/PathwayBrowser/#/R-XTR-5138432 DVL2 is phosphorylated by PKC IEA Xenopus tropicalis 456216 R-XTR-5195402 https://reactome.org/PathwayBrowser/#/R-XTR-5195402 CDK1 phosphorylates LPIN IEA Xenopus tropicalis 456216 R-XTR-5218642 https://reactome.org/PathwayBrowser/#/R-XTR-5218642 PTK2 autophosphorylates IEA Xenopus tropicalis 456216 R-XTR-5218804 https://reactome.org/PathwayBrowser/#/R-XTR-5218804 p38 MAPK activation by VEGFR IEA Xenopus tropicalis 456216 R-XTR-5218805 https://reactome.org/PathwayBrowser/#/R-XTR-5218805 PKC autophosphorylates IEA Xenopus tropicalis 456216 R-XTR-5218806 https://reactome.org/PathwayBrowser/#/R-XTR-5218806 FYN autophosphorylates IEA Xenopus tropicalis 456216 R-XTR-5218812 https://reactome.org/PathwayBrowser/#/R-XTR-5218812 FYN phosphorylates PAK2 IEA Xenopus tropicalis 456216 R-XTR-5218814 https://reactome.org/PathwayBrowser/#/R-XTR-5218814 PAK2 autophorylates IEA Xenopus tropicalis 456216 R-XTR-5218819 https://reactome.org/PathwayBrowser/#/R-XTR-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-5218821 https://reactome.org/PathwayBrowser/#/R-XTR-5218821 PDK1 phosphorylates PKC IEA Xenopus tropicalis 456216 R-XTR-5218854 https://reactome.org/PathwayBrowser/#/R-XTR-5218854 p-Y420-FYN is phosphorylated on S21 IEA Xenopus tropicalis 456216 R-XTR-5229194 https://reactome.org/PathwayBrowser/#/R-XTR-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Xenopus tropicalis 456216 R-XTR-5244669 https://reactome.org/PathwayBrowser/#/R-XTR-5244669 CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments IEA Xenopus tropicalis 456216 R-XTR-5251955 https://reactome.org/PathwayBrowser/#/R-XTR-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Xenopus tropicalis 456216 R-XTR-5251959 https://reactome.org/PathwayBrowser/#/R-XTR-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Xenopus tropicalis 456216 R-XTR-5251989 https://reactome.org/PathwayBrowser/#/R-XTR-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Xenopus tropicalis 456216 R-XTR-5252079 https://reactome.org/PathwayBrowser/#/R-XTR-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Xenopus tropicalis 456216 R-XTR-5357472 https://reactome.org/PathwayBrowser/#/R-XTR-5357472 PAK1-3 autophosphorylates IEA Xenopus tropicalis 456216 R-XTR-5357477 https://reactome.org/PathwayBrowser/#/R-XTR-5357477 PAK1-3 phosphorylates VE-cadherin IEA Xenopus tropicalis 456216 R-XTR-5362459 https://reactome.org/PathwayBrowser/#/R-XTR-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Xenopus tropicalis 456216 R-XTR-5607722 https://reactome.org/PathwayBrowser/#/R-XTR-5607722 Active NIK phosphorylates IKKA dimer IEA Xenopus tropicalis 456216 R-XTR-5607726 https://reactome.org/PathwayBrowser/#/R-XTR-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Xenopus tropicalis 456216 R-XTR-5607740 https://reactome.org/PathwayBrowser/#/R-XTR-5607740 PKC-delta phosphorylates CARD9 IEA Xenopus tropicalis 456216 R-XTR-5610720 https://reactome.org/PathwayBrowser/#/R-XTR-5610720 PKA phosphorylates GLI3 IEA Xenopus tropicalis 456216 R-XTR-5617179 https://reactome.org/PathwayBrowser/#/R-XTR-5617179 PRKACA phosphorylates TNNI3 IEA Xenopus tropicalis 456216 R-XTR-5617182 https://reactome.org/PathwayBrowser/#/R-XTR-5617182 PRKACA phosphorylates PLN IEA Xenopus tropicalis 456216 R-XTR-5618107 https://reactome.org/PathwayBrowser/#/R-XTR-5618107 ATP binding to HSP90 triggers conformation change IEA Xenopus tropicalis 456216 R-XTR-5621363 https://reactome.org/PathwayBrowser/#/R-XTR-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Xenopus tropicalis 456216 R-XTR-5623667 https://reactome.org/PathwayBrowser/#/R-XTR-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Xenopus tropicalis 456216 R-XTR-5624486 https://reactome.org/PathwayBrowser/#/R-XTR-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Xenopus tropicalis 456216 R-XTR-5624492 https://reactome.org/PathwayBrowser/#/R-XTR-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Xenopus tropicalis 456216 R-XTR-5627775 https://reactome.org/PathwayBrowser/#/R-XTR-5627775 Autophosphorylation of PAK1,2,3 IEA Xenopus tropicalis 456216 R-XTR-5654149 https://reactome.org/PathwayBrowser/#/R-XTR-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Xenopus tropicalis 456216 R-XTR-5654151 https://reactome.org/PathwayBrowser/#/R-XTR-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Xenopus tropicalis 456216 R-XTR-5654418 https://reactome.org/PathwayBrowser/#/R-XTR-5654418 Activated FGFR4 phosphorylates FRS2 IEA Xenopus tropicalis 456216 R-XTR-5654428 https://reactome.org/PathwayBrowser/#/R-XTR-5654428 Activated FGFR4 phosphorylates SHC1 IEA Xenopus tropicalis 456216 R-XTR-5654560 https://reactome.org/PathwayBrowser/#/R-XTR-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. IEA Xenopus tropicalis 456216 R-XTR-5654566 https://reactome.org/PathwayBrowser/#/R-XTR-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. IEA Xenopus tropicalis 456216 R-XTR-5654575 https://reactome.org/PathwayBrowser/#/R-XTR-5654575 Activated FGFR1 phosphorylates FRS2 IEA Xenopus tropicalis 456216 R-XTR-5654578 https://reactome.org/PathwayBrowser/#/R-XTR-5654578 Activated FGFR1 phosphorylates FRS3 IEA Xenopus tropicalis 456216 R-XTR-5654582 https://reactome.org/PathwayBrowser/#/R-XTR-5654582 Activated FGFR1 phosphorylates SHC1 IEA Xenopus tropicalis 456216 R-XTR-5654587 https://reactome.org/PathwayBrowser/#/R-XTR-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Xenopus tropicalis 456216 R-XTR-5654607 https://reactome.org/PathwayBrowser/#/R-XTR-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Xenopus tropicalis 456216 R-XTR-5654631 https://reactome.org/PathwayBrowser/#/R-XTR-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Xenopus tropicalis 456216 R-XTR-5654653 https://reactome.org/PathwayBrowser/#/R-XTR-5654653 Activated FGFR4 phosphorylates FRS3 IEA Xenopus tropicalis 456216 R-XTR-5654655 https://reactome.org/PathwayBrowser/#/R-XTR-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Xenopus tropicalis 456216 R-XTR-5654690 https://reactome.org/PathwayBrowser/#/R-XTR-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-5654692 https://reactome.org/PathwayBrowser/#/R-XTR-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-5654697 https://reactome.org/PathwayBrowser/#/R-XTR-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-5654701 https://reactome.org/PathwayBrowser/#/R-XTR-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-5654705 https://reactome.org/PathwayBrowser/#/R-XTR-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-5654709 https://reactome.org/PathwayBrowser/#/R-XTR-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-5654714 https://reactome.org/PathwayBrowser/#/R-XTR-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-5654717 https://reactome.org/PathwayBrowser/#/R-XTR-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-5654989 https://reactome.org/PathwayBrowser/#/R-XTR-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Xenopus tropicalis 456216 R-XTR-5662466 https://reactome.org/PathwayBrowser/#/R-XTR-5662466 XYLB phosphorylates D-xylulose IEA Xenopus tropicalis 456216 R-XTR-5665868 https://reactome.org/PathwayBrowser/#/R-XTR-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Xenopus tropicalis 456216 R-XTR-5668545 https://reactome.org/PathwayBrowser/#/R-XTR-5668545 NIK autophosphorylates on T559 IEA Xenopus tropicalis 456216 R-XTR-5668947 https://reactome.org/PathwayBrowser/#/R-XTR-5668947 PAK1 phosphorylates myosin phosphatase IEA Xenopus tropicalis 456216 R-XTR-5669250 https://reactome.org/PathwayBrowser/#/R-XTR-5669250 PAK1 phosphorylates FLNA IEA Xenopus tropicalis 456216 R-XTR-5672008 https://reactome.org/PathwayBrowser/#/R-XTR-5672008 Thr-180 of ULK1 is phosphorylated IEA Xenopus tropicalis 456216 R-XTR-5672010 https://reactome.org/PathwayBrowser/#/R-XTR-5672010 Active MTORC1 phosphorylates ULK1 IEA Xenopus tropicalis 456216 R-XTR-5672012 https://reactome.org/PathwayBrowser/#/R-XTR-5672012 Beclin-1 complex phosphorylates PtdIns IEA Xenopus tropicalis 456216 R-XTR-5672027 https://reactome.org/PathwayBrowser/#/R-XTR-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Xenopus tropicalis 456216 R-XTR-5672828 https://reactome.org/PathwayBrowser/#/R-XTR-5672828 mTORC1 phosphorylates AKT1S1 IEA Xenopus tropicalis 456216 R-XTR-5675194 https://reactome.org/PathwayBrowser/#/R-XTR-5675194 Activated MAPK phosphorylates RAF1 IEA Xenopus tropicalis 456216 R-XTR-5675868 https://reactome.org/PathwayBrowser/#/R-XTR-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Xenopus tropicalis 456216 R-XTR-5678863 https://reactome.org/PathwayBrowser/#/R-XTR-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Xenopus tropicalis 456216 R-XTR-5679041 https://reactome.org/PathwayBrowser/#/R-XTR-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 456216 R-XTR-5679205 https://reactome.org/PathwayBrowser/#/R-XTR-5679205 ULK1 phosphorylates Beclin-1 IEA Xenopus tropicalis 456216 R-XTR-5682101 https://reactome.org/PathwayBrowser/#/R-XTR-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Xenopus tropicalis 456216 R-XTR-5683714 https://reactome.org/PathwayBrowser/#/R-XTR-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Xenopus tropicalis 456216 R-XTR-5683792 https://reactome.org/PathwayBrowser/#/R-XTR-5683792 p-T68-CHEK2 autophosphorylates IEA Xenopus tropicalis 456216 R-XTR-5684261 https://reactome.org/PathwayBrowser/#/R-XTR-5684261 MAP3K8 is phosphorylated IEA Xenopus tropicalis 456216 R-XTR-5685156 https://reactome.org/PathwayBrowser/#/R-XTR-5685156 ATR phosphorylates RPA2 IEA Xenopus tropicalis 456216 R-XTR-5686587 https://reactome.org/PathwayBrowser/#/R-XTR-5686587 ABL1 phosphorylates RAD52 IEA Xenopus tropicalis 456216 R-XTR-5687086 https://reactome.org/PathwayBrowser/#/R-XTR-5687086 PAK1,2,3 phosphorylates MAPK6,4 IEA Xenopus tropicalis 456216 R-XTR-5687090 https://reactome.org/PathwayBrowser/#/R-XTR-5687090 p-S MAPK6 phosphorylates NCOA3 IEA Xenopus tropicalis 456216 R-XTR-5690996 https://reactome.org/PathwayBrowser/#/R-XTR-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Xenopus tropicalis 456216 R-XTR-5692462 https://reactome.org/PathwayBrowser/#/R-XTR-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Xenopus tropicalis 456216 R-XTR-5692480 https://reactome.org/PathwayBrowser/#/R-XTR-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Xenopus tropicalis 456216 R-XTR-5692755 https://reactome.org/PathwayBrowser/#/R-XTR-5692755 CDK1 phosphorylates MAPK6 IEA Xenopus tropicalis 456216 R-XTR-5693148 https://reactome.org/PathwayBrowser/#/R-XTR-5693148 BCKDK phosphorylates BCKDH IEA Xenopus tropicalis 456216 R-XTR-5696021 https://reactome.org/PathwayBrowser/#/R-XTR-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Xenopus tropicalis 456216 R-XTR-5696074 https://reactome.org/PathwayBrowser/#/R-XTR-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Xenopus tropicalis 456216 R-XTR-5696839 https://reactome.org/PathwayBrowser/#/R-XTR-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Xenopus tropicalis 456216 R-XTR-6782131 https://reactome.org/PathwayBrowser/#/R-XTR-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Xenopus tropicalis 456216 R-XTR-6784006 https://reactome.org/PathwayBrowser/#/R-XTR-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Xenopus tropicalis 456216 R-XTR-6784319 https://reactome.org/PathwayBrowser/#/R-XTR-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Xenopus tropicalis 456216 R-XTR-6784324 https://reactome.org/PathwayBrowser/#/R-XTR-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Xenopus tropicalis 456216 R-XTR-6786245 https://reactome.org/PathwayBrowser/#/R-XTR-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Xenopus tropicalis 456216 R-XTR-6787540 https://reactome.org/PathwayBrowser/#/R-XTR-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Xenopus tropicalis 456216 R-XTR-6788798 https://reactome.org/PathwayBrowser/#/R-XTR-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 456216 R-XTR-6788810 https://reactome.org/PathwayBrowser/#/R-XTR-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 456216 R-XTR-6788855 https://reactome.org/PathwayBrowser/#/R-XTR-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Xenopus tropicalis 456216 R-XTR-6788867 https://reactome.org/PathwayBrowser/#/R-XTR-6788867 FN3K phosphorylates ketosamines IEA Xenopus tropicalis 456216 R-XTR-6793661 https://reactome.org/PathwayBrowser/#/R-XTR-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Xenopus tropicalis 456216 R-XTR-6797606 https://reactome.org/PathwayBrowser/#/R-XTR-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Xenopus tropicalis 456216 R-XTR-6799332 https://reactome.org/PathwayBrowser/#/R-XTR-6799332 ATR phosphorylates TP53 IEA Xenopus tropicalis 456216 R-XTR-6801342 https://reactome.org/PathwayBrowser/#/R-XTR-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Xenopus tropicalis 456216 R-XTR-6801456 https://reactome.org/PathwayBrowser/#/R-XTR-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Xenopus tropicalis 456216 R-XTR-6801675 https://reactome.org/PathwayBrowser/#/R-XTR-6801675 PLK2 phosphorylates NPM1 IEA Xenopus tropicalis 456216 R-XTR-6803545 https://reactome.org/PathwayBrowser/#/R-XTR-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Xenopus tropicalis 456216 R-XTR-6805059 https://reactome.org/PathwayBrowser/#/R-XTR-6805059 CK2:FACT phosphorylates TP53 IEA Xenopus tropicalis 456216 R-XTR-6805103 https://reactome.org/PathwayBrowser/#/R-XTR-6805103 AURKA phosphorylates TP53 IEA Xenopus tropicalis 456216 R-XTR-6805109 https://reactome.org/PathwayBrowser/#/R-XTR-6805109 CDK2 phosphorylates TP53 IEA Xenopus tropicalis 456216 R-XTR-6805126 https://reactome.org/PathwayBrowser/#/R-XTR-6805126 AURKB phosphorylates TP53 IEA Xenopus tropicalis 456216 R-XTR-6805276 https://reactome.org/PathwayBrowser/#/R-XTR-6805276 CDK5 phosphorylates TP53 IEA Xenopus tropicalis 456216 R-XTR-6805285 https://reactome.org/PathwayBrowser/#/R-XTR-6805285 PLK3 phosphorylates TP53 IEA Xenopus tropicalis 456216 R-XTR-6805399 https://reactome.org/PathwayBrowser/#/R-XTR-6805399 TAF1 phosphorylates TP53 IEA Xenopus tropicalis 456216 R-XTR-6805479 https://reactome.org/PathwayBrowser/#/R-XTR-6805479 TP53RK phosphorylates TP53 IEA Xenopus tropicalis 456216 R-XTR-6805507 https://reactome.org/PathwayBrowser/#/R-XTR-6805507 APAF1 binds AVEN IEA Xenopus tropicalis 456216 R-XTR-6806877 https://reactome.org/PathwayBrowser/#/R-XTR-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Xenopus tropicalis 456216 R-XTR-6806967 https://reactome.org/PathwayBrowser/#/R-XTR-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Xenopus tropicalis 456216 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 456216 R-XTR-6810233 https://reactome.org/PathwayBrowser/#/R-XTR-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Xenopus tropicalis 456216 R-XTR-6810472 https://reactome.org/PathwayBrowser/#/R-XTR-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Xenopus tropicalis 456216 R-XTR-6811522 https://reactome.org/PathwayBrowser/#/R-XTR-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Xenopus tropicalis 456216 R-XTR-6814119 https://reactome.org/PathwayBrowser/#/R-XTR-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Xenopus tropicalis 456216 R-XTR-6814120 https://reactome.org/PathwayBrowser/#/R-XTR-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Xenopus tropicalis 456216 R-XTR-6814121 https://reactome.org/PathwayBrowser/#/R-XTR-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Xenopus tropicalis 456216 R-XTR-6814124 https://reactome.org/PathwayBrowser/#/R-XTR-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Xenopus tropicalis 456216 R-XTR-68944 https://reactome.org/PathwayBrowser/#/R-XTR-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Xenopus tropicalis 456216 R-XTR-69005 https://reactome.org/PathwayBrowser/#/R-XTR-69005 Cdc6 protein is phosphorylated by CDK IEA Xenopus tropicalis 456216 R-XTR-69195 https://reactome.org/PathwayBrowser/#/R-XTR-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Xenopus tropicalis 456216 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 456216 R-XTR-69608 https://reactome.org/PathwayBrowser/#/R-XTR-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Xenopus tropicalis 456216 R-XTR-69685 https://reactome.org/PathwayBrowser/#/R-XTR-69685 CHEK2 phosphorylates TP53 IEA Xenopus tropicalis 456216 R-XTR-70355 https://reactome.org/PathwayBrowser/#/R-XTR-70355 GALK1 phosphorylates Gal to Gal1P IEA Xenopus tropicalis 456216 R-XTR-70420 https://reactome.org/PathwayBrowser/#/R-XTR-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Xenopus tropicalis 456216 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 456216 R-XTR-70555 https://reactome.org/PathwayBrowser/#/R-XTR-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Xenopus tropicalis 456216 R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Xenopus tropicalis 456216 R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Xenopus tropicalis 456216 R-XTR-70606 https://reactome.org/PathwayBrowser/#/R-XTR-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Xenopus tropicalis 456216 R-XTR-70773 https://reactome.org/PathwayBrowser/#/R-XTR-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Xenopus tropicalis 456216 R-XTR-70997 https://reactome.org/PathwayBrowser/#/R-XTR-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Xenopus tropicalis 456216 R-XTR-71031 https://reactome.org/PathwayBrowser/#/R-XTR-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Xenopus tropicalis 456216 R-XTR-71401 https://reactome.org/PathwayBrowser/#/R-XTR-71401 OGDH dimer decarboxylates 2-OG IEA Xenopus tropicalis 456216 R-XTR-71588 https://reactome.org/PathwayBrowser/#/R-XTR-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Xenopus tropicalis 456216 R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 456216 R-XTR-71802 https://reactome.org/PathwayBrowser/#/R-XTR-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Xenopus tropicalis 456216 R-XTR-72621 https://reactome.org/PathwayBrowser/#/R-XTR-72621 Ribosomal scanning IEA Xenopus tropicalis 456216 R-XTR-727819 https://reactome.org/PathwayBrowser/#/R-XTR-727819 TAK1 phosphorylates MKK6 IEA Xenopus tropicalis 456216 R-XTR-73577 https://reactome.org/PathwayBrowser/#/R-XTR-73577 CAD hexamer transforms L-Gln to CAP IEA Xenopus tropicalis 456216 R-XTR-73598 https://reactome.org/PathwayBrowser/#/R-XTR-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Xenopus tropicalis 456216 R-XTR-73599 https://reactome.org/PathwayBrowser/#/R-XTR-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Xenopus tropicalis 456216 R-XTR-73632 https://reactome.org/PathwayBrowser/#/R-XTR-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Xenopus tropicalis 456216 R-XTR-73635 https://reactome.org/PathwayBrowser/#/R-XTR-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Xenopus tropicalis 456216 R-XTR-73788 https://reactome.org/PathwayBrowser/#/R-XTR-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Xenopus tropicalis 456216 R-XTR-73805 https://reactome.org/PathwayBrowser/#/R-XTR-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Xenopus tropicalis 456216 R-XTR-73810 https://reactome.org/PathwayBrowser/#/R-XTR-73810 FGAM + ATP => AIR + ADP + Pi IEA Xenopus tropicalis 456216 R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 456216 R-XTR-73814 https://reactome.org/PathwayBrowser/#/R-XTR-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Xenopus tropicalis 456216 R-XTR-74207 https://reactome.org/PathwayBrowser/#/R-XTR-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Xenopus tropicalis 456216 R-XTR-74711 https://reactome.org/PathwayBrowser/#/R-XTR-74711 Phosphorylation of IRS IEA Xenopus tropicalis 456216 R-XTR-74715 https://reactome.org/PathwayBrowser/#/R-XTR-74715 Autophosphorylation of insulin receptor IEA Xenopus tropicalis 456216 R-XTR-74742 https://reactome.org/PathwayBrowser/#/R-XTR-74742 Phosphorylation of SHC1 IEA Xenopus tropicalis 456216 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 456216 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 456216 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 456216 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 456216 R-XTR-75126 https://reactome.org/PathwayBrowser/#/R-XTR-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Xenopus tropicalis 456216 R-XTR-75848 https://reactome.org/PathwayBrowser/#/R-XTR-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Xenopus tropicalis 456216 R-XTR-75851 https://reactome.org/PathwayBrowser/#/R-XTR-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 456216 R-XTR-75887 https://reactome.org/PathwayBrowser/#/R-XTR-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Xenopus tropicalis 456216 R-XTR-75949 https://reactome.org/PathwayBrowser/#/R-XTR-75949 RNA Polymerase II Promoter Opening: First Transition IEA Xenopus tropicalis 456216 R-XTR-77071 https://reactome.org/PathwayBrowser/#/R-XTR-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Xenopus tropicalis 456216 R-XTR-8847977 https://reactome.org/PathwayBrowser/#/R-XTR-8847977 FRK phosphorylates PTEN IEA Xenopus tropicalis 456216 R-XTR-8848053 https://reactome.org/PathwayBrowser/#/R-XTR-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Xenopus tropicalis 456216 R-XTR-8848436 https://reactome.org/PathwayBrowser/#/R-XTR-8848436 PTK6 phosphorylates CDKN1B IEA Xenopus tropicalis 456216 R-XTR-8848726 https://reactome.org/PathwayBrowser/#/R-XTR-8848726 PTK6 phosphorylates BCAR1 IEA Xenopus tropicalis 456216 R-XTR-8848975 https://reactome.org/PathwayBrowser/#/R-XTR-8848975 PTK6 phosphorylates KHDRBS1 IEA Xenopus tropicalis 456216 R-XTR-8849032 https://reactome.org/PathwayBrowser/#/R-XTR-8849032 PTK6 phosphorylates KHDRBS2 IEA Xenopus tropicalis 456216 R-XTR-8849042 https://reactome.org/PathwayBrowser/#/R-XTR-8849042 PTK6 phosphorylates KHDRBS3 IEA Xenopus tropicalis 456216 R-XTR-8849068 https://reactome.org/PathwayBrowser/#/R-XTR-8849068 PTK6 phosphorylates ARHGAP35 IEA Xenopus tropicalis 456216 R-XTR-8849463 https://reactome.org/PathwayBrowser/#/R-XTR-8849463 PTK6 phosphorylates SFPQ IEA Xenopus tropicalis 456216 R-XTR-8850527 https://reactome.org/PathwayBrowser/#/R-XTR-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Xenopus tropicalis 456216 R-XTR-8850534 https://reactome.org/PathwayBrowser/#/R-XTR-8850534 PDCL promotes G-protein beta 5 folding IEA Xenopus tropicalis 456216 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 456216 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 456216 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 456216 R-XTR-8851797 https://reactome.org/PathwayBrowser/#/R-XTR-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Xenopus tropicalis 456216 R-XTR-8851890 https://reactome.org/PathwayBrowser/#/R-XTR-8851890 MET phosphorylates SHC1-2 IEA Xenopus tropicalis 456216 R-XTR-8851933 https://reactome.org/PathwayBrowser/#/R-XTR-8851933 MET phosphorylates GAB1 IEA Xenopus tropicalis 456216 R-XTR-8852019 https://reactome.org/PathwayBrowser/#/R-XTR-8852019 MET bound PI3K generates PIP3 IEA Xenopus tropicalis 456216 R-XTR-8852306 https://reactome.org/PathwayBrowser/#/R-XTR-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Xenopus tropicalis 456216 R-XTR-8852317 https://reactome.org/PathwayBrowser/#/R-XTR-8852317 PLK1 phosphorylates GTSE1 IEA Xenopus tropicalis 456216 R-XTR-8852552 https://reactome.org/PathwayBrowser/#/R-XTR-8852552 MST1R autophosphorylates IEA Xenopus tropicalis 456216 R-XTR-8853419 https://reactome.org/PathwayBrowser/#/R-XTR-8853419 TPX2 promotes AURKA autophosphorylation IEA Xenopus tropicalis 456216 R-XTR-8853444 https://reactome.org/PathwayBrowser/#/R-XTR-8853444 AURKA phosphorylates PHLDA1 IEA Xenopus tropicalis 456216 R-XTR-8853774 https://reactome.org/PathwayBrowser/#/R-XTR-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Xenopus tropicalis 456216 R-XTR-8857555 https://reactome.org/PathwayBrowser/#/R-XTR-8857555 EGFR phosphorylates GPNMB IEA Xenopus tropicalis 456216 R-XTR-8857577 https://reactome.org/PathwayBrowser/#/R-XTR-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Xenopus tropicalis 456216 R-XTR-8857583 https://reactome.org/PathwayBrowser/#/R-XTR-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Xenopus tropicalis 456216 R-XTR-8865774 https://reactome.org/PathwayBrowser/#/R-XTR-8865774 TTLLs polyglutamylate tubulin IEA Xenopus tropicalis 456216 R-XTR-8866268 https://reactome.org/PathwayBrowser/#/R-XTR-8866268 ADBRK1,2 phosphorylate AVPR2 IEA Xenopus tropicalis 456216 R-XTR-8866542 https://reactome.org/PathwayBrowser/#/R-XTR-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Xenopus tropicalis 456216 R-XTR-8867370 https://reactome.org/PathwayBrowser/#/R-XTR-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Xenopus tropicalis 456216 R-XTR-8868066 https://reactome.org/PathwayBrowser/#/R-XTR-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Xenopus tropicalis 456216 R-XTR-8868118 https://reactome.org/PathwayBrowser/#/R-XTR-8868118 MAPK12 phosphorylates PTPN3 IEA Xenopus tropicalis 456216 R-XTR-8875451 https://reactome.org/PathwayBrowser/#/R-XTR-8875451 MET phosphorylates CBL IEA Xenopus tropicalis 456216 R-XTR-8875817 https://reactome.org/PathwayBrowser/#/R-XTR-8875817 MET phosphorylates STAT3 IEA Xenopus tropicalis 456216 R-XTR-8876889 https://reactome.org/PathwayBrowser/#/R-XTR-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 456216 R-XTR-8877691 https://reactome.org/PathwayBrowser/#/R-XTR-8877691 MAP2K6 phosphorylates PIP4K2B IEA Xenopus tropicalis 456216 R-XTR-8931653 https://reactome.org/PathwayBrowser/#/R-XTR-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Xenopus tropicalis 456216 R-XTR-8940100 https://reactome.org/PathwayBrowser/#/R-XTR-8940100 CDK1 phosphorylates VCPIP1 IEA Xenopus tropicalis 456216 R-XTR-8942575 https://reactome.org/PathwayBrowser/#/R-XTR-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Xenopus tropicalis 456216 R-XTR-8942607 https://reactome.org/PathwayBrowser/#/R-XTR-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Xenopus tropicalis 456216 R-XTR-8942836 https://reactome.org/PathwayBrowser/#/R-XTR-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Xenopus tropicalis 456216 R-XTR-8948146 https://reactome.org/PathwayBrowser/#/R-XTR-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Xenopus tropicalis 456216 R-XTR-8950340 https://reactome.org/PathwayBrowser/#/R-XTR-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Xenopus tropicalis 456216 R-XTR-8950405 https://reactome.org/PathwayBrowser/#/R-XTR-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Xenopus tropicalis 456216 R-XTR-8950453 https://reactome.org/PathwayBrowser/#/R-XTR-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Xenopus tropicalis 456216 R-XTR-8950485 https://reactome.org/PathwayBrowser/#/R-XTR-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Xenopus tropicalis 456216 R-XTR-8950537 https://reactome.org/PathwayBrowser/#/R-XTR-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Xenopus tropicalis 456216 R-XTR-8952289 https://reactome.org/PathwayBrowser/#/R-XTR-8952289 FAM20C phosphorylates FAM20C substrates IEA Xenopus tropicalis 456216 R-XTR-8954327 https://reactome.org/PathwayBrowser/#/R-XTR-8954327 UCKL1 phosphorylates urindine, cytidine IEA Xenopus tropicalis 456216 R-XTR-8955030 https://reactome.org/PathwayBrowser/#/R-XTR-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 456216 R-XTR-8955844 https://reactome.org/PathwayBrowser/#/R-XTR-8955844 RBKS phosphorylates ribose to R5P IEA Xenopus tropicalis 456216 R-XTR-8956659 https://reactome.org/PathwayBrowser/#/R-XTR-8956659 ABL1 phosphorylates YAP1 IEA Xenopus tropicalis 456216 R-XTR-8959719 https://reactome.org/PathwayBrowser/#/R-XTR-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Xenopus tropicalis 456216 R-XTR-8983834 https://reactome.org/PathwayBrowser/#/R-XTR-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Xenopus tropicalis 456216 R-XTR-8983835 https://reactome.org/PathwayBrowser/#/R-XTR-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Xenopus tropicalis 456216 R-XTR-8983870 https://reactome.org/PathwayBrowser/#/R-XTR-8983870 JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated IEA Xenopus tropicalis 456216 R-XTR-8983872 https://reactome.org/PathwayBrowser/#/R-XTR-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Xenopus tropicalis 456216 R-XTR-8984012 https://reactome.org/PathwayBrowser/#/R-XTR-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Xenopus tropicalis 456216 R-XTR-8984014 https://reactome.org/PathwayBrowser/#/R-XTR-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Xenopus tropicalis 456216 R-XTR-8986985 https://reactome.org/PathwayBrowser/#/R-XTR-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Xenopus tropicalis 456216 R-XTR-8986994 https://reactome.org/PathwayBrowser/#/R-XTR-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Xenopus tropicalis 456216 R-XTR-8986995 https://reactome.org/PathwayBrowser/#/R-XTR-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Xenopus tropicalis 456216 R-XTR-8987040 https://reactome.org/PathwayBrowser/#/R-XTR-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Xenopus tropicalis 456216 R-XTR-8987042 https://reactome.org/PathwayBrowser/#/R-XTR-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Xenopus tropicalis 456216 R-XTR-8987070 https://reactome.org/PathwayBrowser/#/R-XTR-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Xenopus tropicalis 456216 R-XTR-8987202 https://reactome.org/PathwayBrowser/#/R-XTR-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Xenopus tropicalis 456216 R-XTR-8987255 https://reactome.org/PathwayBrowser/#/R-XTR-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Xenopus tropicalis 456216 R-XTR-9008684 https://reactome.org/PathwayBrowser/#/R-XTR-9008684 TBK1 phosphorylation IEA Xenopus tropicalis 456216 R-XTR-9009072 https://reactome.org/PathwayBrowser/#/R-XTR-9009072 STAT3 phosphorylation IEA Xenopus tropicalis 456216 R-XTR-9012319 https://reactome.org/PathwayBrowser/#/R-XTR-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Xenopus tropicalis 456216 R-XTR-9018572 https://reactome.org/PathwayBrowser/#/R-XTR-9018572 EGFR phosphorylates NOTCH3 IEA Xenopus tropicalis 456216 R-XTR-9021627 https://reactome.org/PathwayBrowser/#/R-XTR-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 456216 R-XTR-9027272 https://reactome.org/PathwayBrowser/#/R-XTR-9027272 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 IEA Xenopus tropicalis 456216 R-XTR-9027273 https://reactome.org/PathwayBrowser/#/R-XTR-9027273 JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 IEA Xenopus tropicalis 456216 R-XTR-909718 https://reactome.org/PathwayBrowser/#/R-XTR-909718 Formation of p-STAT1 homodimer IEA Xenopus tropicalis 456216 R-XTR-909729 https://reactome.org/PathwayBrowser/#/R-XTR-909729 Activation of JAK kinases IEA Xenopus tropicalis 456216 R-XTR-909730 https://reactome.org/PathwayBrowser/#/R-XTR-909730 Phosphorylation of INFAR1 by TYK2 IEA Xenopus tropicalis 456216 R-XTR-909732 https://reactome.org/PathwayBrowser/#/R-XTR-909732 Phosphorylation of STAT2 IEA Xenopus tropicalis 456216 R-XTR-913996 https://reactome.org/PathwayBrowser/#/R-XTR-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Xenopus tropicalis 456216 R-XTR-917693 https://reactome.org/PathwayBrowser/#/R-XTR-917693 ESCRT Disassembly IEA Xenopus tropicalis 456216 R-XTR-917841 https://reactome.org/PathwayBrowser/#/R-XTR-917841 Acidification of Tf:TfR1 containing endosome IEA Xenopus tropicalis 456216 R-XTR-917979 https://reactome.org/PathwayBrowser/#/R-XTR-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Xenopus tropicalis 456216 R-XTR-927889 https://reactome.org/PathwayBrowser/#/R-XTR-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Xenopus tropicalis 456216 R-XTR-934559 https://reactome.org/PathwayBrowser/#/R-XTR-934559 SPRY2 is phosphorylated by phosphorylated MNK1 IEA Xenopus tropicalis 456216 R-XTR-936802 https://reactome.org/PathwayBrowser/#/R-XTR-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Xenopus tropicalis 456216 R-XTR-936883 https://reactome.org/PathwayBrowser/#/R-XTR-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Xenopus tropicalis 456216 R-XTR-936895 https://reactome.org/PathwayBrowser/#/R-XTR-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Xenopus tropicalis 456216 R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 456216 R-XTR-936991 https://reactome.org/PathwayBrowser/#/R-XTR-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Xenopus tropicalis 456216 R-XTR-937311 https://reactome.org/PathwayBrowser/#/R-XTR-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 456216 R-XTR-939763 https://reactome.org/PathwayBrowser/#/R-XTR-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Xenopus tropicalis 456216 R-XTR-947591 https://reactome.org/PathwayBrowser/#/R-XTR-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Xenopus tropicalis 456216 R-XTR-9606884 https://reactome.org/PathwayBrowser/#/R-XTR-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Xenopus tropicalis 456216 R-XTR-9624800 https://reactome.org/PathwayBrowser/#/R-XTR-9624800 CDK1 phosphorylates LBR IEA Xenopus tropicalis 456216 R-XTR-9626817 https://reactome.org/PathwayBrowser/#/R-XTR-9626817 PKC phosphorylates NCF1 IEA Xenopus tropicalis 456216 R-XTR-9626832 https://reactome.org/PathwayBrowser/#/R-XTR-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Xenopus tropicalis 456216 R-XTR-9626880 https://reactome.org/PathwayBrowser/#/R-XTR-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Xenopus tropicalis 456216 R-XTR-9627089 https://reactome.org/PathwayBrowser/#/R-XTR-9627089 CASP9 is phosphorylated at T412 IEA Xenopus tropicalis 456216 R-XTR-9634702 https://reactome.org/PathwayBrowser/#/R-XTR-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Xenopus tropicalis 456216 R-XTR-9645442 https://reactome.org/PathwayBrowser/#/R-XTR-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Xenopus tropicalis 456216 R-XTR-9645535 https://reactome.org/PathwayBrowser/#/R-XTR-9645535 ALPK1 phosphorylates TIFA IEA Xenopus tropicalis 456216 R-XTR-964958 https://reactome.org/PathwayBrowser/#/R-XTR-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Xenopus tropicalis 456216 R-XTR-964962 https://reactome.org/PathwayBrowser/#/R-XTR-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Xenopus tropicalis 456216 R-XTR-964970 https://reactome.org/PathwayBrowser/#/R-XTR-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Xenopus tropicalis 456216 R-XTR-9650858 https://reactome.org/PathwayBrowser/#/R-XTR-9650858 Meglitinides bind ABCC8 IEA Xenopus tropicalis 456216 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 456216 R-XTR-9661417 https://reactome.org/PathwayBrowser/#/R-XTR-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 456216 R-XTR-9668419 https://reactome.org/PathwayBrowser/#/R-XTR-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Xenopus tropicalis 456216 R-XTR-9684118 https://reactome.org/PathwayBrowser/#/R-XTR-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Xenopus tropicalis 456216 R-XTR-9686521 https://reactome.org/PathwayBrowser/#/R-XTR-9686521 CDK2:CCNA phosphorylates TERF2 IEA Xenopus tropicalis 456216 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 456216 R-XTR-9727198 https://reactome.org/PathwayBrowser/#/R-XTR-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 456216 R-XTR-9731111 https://reactome.org/PathwayBrowser/#/R-XTR-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Xenopus tropicalis 456216 R-XTR-9734547 https://reactome.org/PathwayBrowser/#/R-XTR-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Xenopus tropicalis 456216 R-XTR-9734687 https://reactome.org/PathwayBrowser/#/R-XTR-9734687 ORC6 is phosphorylated on T195 IEA Xenopus tropicalis 456216 R-XTR-9748949 https://reactome.org/PathwayBrowser/#/R-XTR-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Xenopus tropicalis 456216 R-XTR-9748963 https://reactome.org/PathwayBrowser/#/R-XTR-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Xenopus tropicalis 456216 R-XTR-9750617 https://reactome.org/PathwayBrowser/#/R-XTR-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Xenopus tropicalis 456216 R-XTR-9750656 https://reactome.org/PathwayBrowser/#/R-XTR-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Xenopus tropicalis 456216 R-XTR-975103 https://reactome.org/PathwayBrowser/#/R-XTR-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Xenopus tropicalis 456216 R-XTR-9753278 https://reactome.org/PathwayBrowser/#/R-XTR-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 456216 R-XTR-9753283 https://reactome.org/PathwayBrowser/#/R-XTR-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 456216 R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 456216 R-XTR-9754974 https://reactome.org/PathwayBrowser/#/R-XTR-9754974 ADK phosphorylates RBV IEA Xenopus tropicalis 456216 R-XTR-9755013 https://reactome.org/PathwayBrowser/#/R-XTR-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Xenopus tropicalis 456216 R-XTR-9794120 https://reactome.org/PathwayBrowser/#/R-XTR-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Xenopus tropicalis 456216 R-XTR-9794572 https://reactome.org/PathwayBrowser/#/R-XTR-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Xenopus tropicalis 456216 R-XTR-9819106 https://reactome.org/PathwayBrowser/#/R-XTR-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Xenopus tropicalis 456216 R-XTR-9824977 https://reactome.org/PathwayBrowser/#/R-XTR-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Xenopus tropicalis 456216 R-XTR-9824994 https://reactome.org/PathwayBrowser/#/R-XTR-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Xenopus tropicalis 456216 R-XTR-982810 https://reactome.org/PathwayBrowser/#/R-XTR-982810 JAK2 phosphorylation IEA Xenopus tropicalis 456216 R-XTR-983259 https://reactome.org/PathwayBrowser/#/R-XTR-983259 Kinesins move along microtubules consuming ATP IEA Xenopus tropicalis 456216 R-XTR-9836159 https://reactome.org/PathwayBrowser/#/R-XTR-9836159 p-PKR dimer phosphorylates DHX9 IEA Xenopus tropicalis 456216 R-XTR-9836184 https://reactome.org/PathwayBrowser/#/R-XTR-9836184 p-PKR dimer phosphorylates CDK1 IEA Xenopus tropicalis 456216 R-XTR-9836322 https://reactome.org/PathwayBrowser/#/R-XTR-9836322 p-PKR dimer phosphorylates MKK6 IEA Xenopus tropicalis 456216 R-XTR-9836362 https://reactome.org/PathwayBrowser/#/R-XTR-9836362 p-PKR dimer phosphorylates TP53 tetramer IEA Xenopus tropicalis 456216 R-XTR-9836383 https://reactome.org/PathwayBrowser/#/R-XTR-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Xenopus tropicalis 456216 R-XTR-9836435 https://reactome.org/PathwayBrowser/#/R-XTR-9836435 p-PKR dimer phosphorylates SNCA IEA Xenopus tropicalis 456216 R-XTR-9837333 https://reactome.org/PathwayBrowser/#/R-XTR-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Xenopus tropicalis 456216 R-XTR-9837337 https://reactome.org/PathwayBrowser/#/R-XTR-9837337 DCAKD phosphorylates DP-CoA IEA Xenopus tropicalis 456216 R-XTR-9838289 https://reactome.org/PathwayBrowser/#/R-XTR-9838289 CLPXP degrades mitochondrial matrix proteins IEA Xenopus tropicalis 456216 R-XTR-9838321 https://reactome.org/PathwayBrowser/#/R-XTR-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Xenopus tropicalis 456216 R-XTR-9839059 https://reactome.org/PathwayBrowser/#/R-XTR-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Xenopus tropicalis 456216 R-XTR-9839105 https://reactome.org/PathwayBrowser/#/R-XTR-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Xenopus tropicalis 456216 R-XTR-9839113 https://reactome.org/PathwayBrowser/#/R-XTR-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Xenopus tropicalis 456216 R-XTR-9842648 https://reactome.org/PathwayBrowser/#/R-XTR-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 IEA Xenopus tropicalis 456216 R-XTR-9842651 https://reactome.org/PathwayBrowser/#/R-XTR-9842651 Active LTK receptor phosphorylates SHC1 IEA Xenopus tropicalis 456216 R-XTR-9842666 https://reactome.org/PathwayBrowser/#/R-XTR-9842666 Active LTK phosphorylates IRS1 IEA Xenopus tropicalis 456216 R-XTR-9843721 https://reactome.org/PathwayBrowser/#/R-XTR-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Xenopus tropicalis 456216 R-XTR-994137 https://reactome.org/PathwayBrowser/#/R-XTR-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Xenopus tropicalis 456216 R-XTR-994140 https://reactome.org/PathwayBrowser/#/R-XTR-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Xenopus tropicalis 45725 R-BTA-141341 https://reactome.org/PathwayBrowser/#/R-BTA-141341 SMOX-3 oxidises SPN to SPM IEA Bos taurus 45725 R-BTA-351207 https://reactome.org/PathwayBrowser/#/R-BTA-351207 Spermine => N-acetylated spermine IEA Bos taurus 45725 R-BTA-351210 https://reactome.org/PathwayBrowser/#/R-BTA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Bos taurus 45725 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 45725 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 45725 R-CEL-351207 https://reactome.org/PathwayBrowser/#/R-CEL-351207 Spermine => N-acetylated spermine IEA Caenorhabditis elegans 45725 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 45725 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 45725 R-CFA-141341 https://reactome.org/PathwayBrowser/#/R-CFA-141341 SMOX-3 oxidises SPN to SPM IEA Canis familiaris 45725 R-CFA-351207 https://reactome.org/PathwayBrowser/#/R-CFA-351207 Spermine => N-acetylated spermine IEA Canis familiaris 45725 R-CFA-351210 https://reactome.org/PathwayBrowser/#/R-CFA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Canis familiaris 45725 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 45725 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 45725 R-DDI-351207 https://reactome.org/PathwayBrowser/#/R-DDI-351207 Spermine => N-acetylated spermine IEA Dictyostelium discoideum 45725 R-DME-141341 https://reactome.org/PathwayBrowser/#/R-DME-141341 SMOX-3 oxidises SPN to SPM IEA Drosophila melanogaster 45725 R-DME-351207 https://reactome.org/PathwayBrowser/#/R-DME-351207 Spermine => N-acetylated spermine IEA Drosophila melanogaster 45725 R-DME-351210 https://reactome.org/PathwayBrowser/#/R-DME-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Drosophila melanogaster 45725 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 45725 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 45725 R-DRE-351207 https://reactome.org/PathwayBrowser/#/R-DRE-351207 Spermine => N-acetylated spermine IEA Danio rerio 45725 R-DRE-351210 https://reactome.org/PathwayBrowser/#/R-DRE-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Danio rerio 45725 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 45725 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 45725 R-GGA-141341 https://reactome.org/PathwayBrowser/#/R-GGA-141341 SMOX-3 oxidises SPN to SPM IEA Gallus gallus 45725 R-GGA-351207 https://reactome.org/PathwayBrowser/#/R-GGA-351207 Spermine => N-acetylated spermine IEA Gallus gallus 45725 R-GGA-351210 https://reactome.org/PathwayBrowser/#/R-GGA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Gallus gallus 45725 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 45725 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 45725 R-HSA-141341 https://reactome.org/PathwayBrowser/#/R-HSA-141341 SMOX-3 oxidises SPN to SPM TAS Homo sapiens 45725 R-HSA-351207 https://reactome.org/PathwayBrowser/#/R-HSA-351207 Spermine => N-acetylated spermine TAS Homo sapiens 45725 R-HSA-351210 https://reactome.org/PathwayBrowser/#/R-HSA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine TAS Homo sapiens 45725 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 45725 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 45725 R-MMU-141341 https://reactome.org/PathwayBrowser/#/R-MMU-141341 SMOX-3 oxidises SPN to SPM IEA Mus musculus 45725 R-MMU-351207 https://reactome.org/PathwayBrowser/#/R-MMU-351207 Spermine => N-acetylated spermine IEA Mus musculus 45725 R-MMU-351210 https://reactome.org/PathwayBrowser/#/R-MMU-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Mus musculus 45725 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 45725 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 45725 R-RNO-141341 https://reactome.org/PathwayBrowser/#/R-RNO-141341 SMOX-3 oxidises SPN to SPM IEA Rattus norvegicus 45725 R-RNO-351207 https://reactome.org/PathwayBrowser/#/R-RNO-351207 Spermine => N-acetylated spermine IEA Rattus norvegicus 45725 R-RNO-351210 https://reactome.org/PathwayBrowser/#/R-RNO-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Rattus norvegicus 45725 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 45725 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 45725 R-SCE-351207 https://reactome.org/PathwayBrowser/#/R-SCE-351207 Spermine => N-acetylated spermine IEA Saccharomyces cerevisiae 45725 R-SPO-351207 https://reactome.org/PathwayBrowser/#/R-SPO-351207 Spermine => N-acetylated spermine IEA Schizosaccharomyces pombe 45725 R-SSC-141341 https://reactome.org/PathwayBrowser/#/R-SSC-141341 SMOX-3 oxidises SPN to SPM IEA Sus scrofa 45725 R-SSC-351207 https://reactome.org/PathwayBrowser/#/R-SSC-351207 Spermine => N-acetylated spermine IEA Sus scrofa 45725 R-SSC-351210 https://reactome.org/PathwayBrowser/#/R-SSC-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Sus scrofa 45725 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 45725 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 45725 R-XTR-141341 https://reactome.org/PathwayBrowser/#/R-XTR-141341 SMOX-3 oxidises SPN to SPM IEA Xenopus tropicalis 45725 R-XTR-351207 https://reactome.org/PathwayBrowser/#/R-XTR-351207 Spermine => N-acetylated spermine IEA Xenopus tropicalis 45725 R-XTR-351210 https://reactome.org/PathwayBrowser/#/R-XTR-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Xenopus tropicalis 45725 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 45725 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 45863 R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 45863 R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 45863 R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 45863 R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 45863 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 45863 R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 45863 R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 45863 R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 45863 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 45980 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 45980 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 45980 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 45980 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 45980 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 45980 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 45980 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 45980 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 45980 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 45980 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 45980 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 45980 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 45980 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 45980 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 45980 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 46020 R-BTA-434650 https://reactome.org/PathwayBrowser/#/R-BTA-434650 MATEs mediate extrusion of xenobiotics IEA Bos taurus 46020 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 46020 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 46020 R-BTA-549304 https://reactome.org/PathwayBrowser/#/R-BTA-549304 OCT3 mediates renal clearance of organic cations IEA Bos taurus 46020 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 46020 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 46020 R-BTA-561072 https://reactome.org/PathwayBrowser/#/R-BTA-561072 OCT3 mediates renal uptake of organic cations IEA Bos taurus 46020 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 46020 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 46020 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans 46020 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 46020 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 46020 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans 46020 R-CFA-434650 https://reactome.org/PathwayBrowser/#/R-CFA-434650 MATEs mediate extrusion of xenobiotics IEA Canis familiaris 46020 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 46020 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 46020 R-CFA-549304 https://reactome.org/PathwayBrowser/#/R-CFA-549304 OCT3 mediates renal clearance of organic cations IEA Canis familiaris 46020 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 46020 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 46020 R-CFA-561072 https://reactome.org/PathwayBrowser/#/R-CFA-561072 OCT3 mediates renal uptake of organic cations IEA Canis familiaris 46020 R-DDI-434650 https://reactome.org/PathwayBrowser/#/R-DDI-434650 MATEs mediate extrusion of xenobiotics IEA Dictyostelium discoideum 46020 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 46020 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 46020 R-DME-549304 https://reactome.org/PathwayBrowser/#/R-DME-549304 OCT3 mediates renal clearance of organic cations IEA Drosophila melanogaster 46020 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 46020 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 46020 R-DME-561072 https://reactome.org/PathwayBrowser/#/R-DME-561072 OCT3 mediates renal uptake of organic cations IEA Drosophila melanogaster 46020 R-DRE-434650 https://reactome.org/PathwayBrowser/#/R-DRE-434650 MATEs mediate extrusion of xenobiotics IEA Danio rerio 46020 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 46020 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 46020 R-DRE-549304 https://reactome.org/PathwayBrowser/#/R-DRE-549304 OCT3 mediates renal clearance of organic cations IEA Danio rerio 46020 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 46020 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 46020 R-DRE-561072 https://reactome.org/PathwayBrowser/#/R-DRE-561072 OCT3 mediates renal uptake of organic cations IEA Danio rerio 46020 R-GGA-434650 https://reactome.org/PathwayBrowser/#/R-GGA-434650 MATEs mediate extrusion of xenobiotics IEA Gallus gallus 46020 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 46020 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 46020 R-GGA-549304 https://reactome.org/PathwayBrowser/#/R-GGA-549304 OCT3 mediates renal clearance of organic cations IEA Gallus gallus 46020 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 46020 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 46020 R-GGA-561072 https://reactome.org/PathwayBrowser/#/R-GGA-561072 OCT3 mediates renal uptake of organic cations IEA Gallus gallus 46020 R-HSA-434650 https://reactome.org/PathwayBrowser/#/R-HSA-434650 MATEs mediate extrusion of xenobiotics TAS Homo sapiens 46020 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 46020 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 46020 R-HSA-549304 https://reactome.org/PathwayBrowser/#/R-HSA-549304 OCT3 mediates renal clearance of organic cations TAS Homo sapiens 46020 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 46020 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 46020 R-HSA-561072 https://reactome.org/PathwayBrowser/#/R-HSA-561072 OCT3 mediates renal uptake of organic cations TAS Homo sapiens 46020 R-MMU-434650 https://reactome.org/PathwayBrowser/#/R-MMU-434650 MATEs mediate extrusion of xenobiotics IEA Mus musculus 46020 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 46020 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 46020 R-MMU-549304 https://reactome.org/PathwayBrowser/#/R-MMU-549304 OCT3 mediates renal clearance of organic cations IEA Mus musculus 46020 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 46020 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 46020 R-MMU-561072 https://reactome.org/PathwayBrowser/#/R-MMU-561072 OCT3 mediates renal uptake of organic cations IEA Mus musculus 46020 R-PFA-434650 https://reactome.org/PathwayBrowser/#/R-PFA-434650 MATEs mediate extrusion of xenobiotics IEA Plasmodium falciparum 46020 R-RNO-434650 https://reactome.org/PathwayBrowser/#/R-RNO-434650 MATEs mediate extrusion of xenobiotics IEA Rattus norvegicus 46020 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 46020 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 46020 R-RNO-549304 https://reactome.org/PathwayBrowser/#/R-RNO-549304 OCT3 mediates renal clearance of organic cations IEA Rattus norvegicus 46020 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 46020 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 46020 R-RNO-561072 https://reactome.org/PathwayBrowser/#/R-RNO-561072 OCT3 mediates renal uptake of organic cations IEA Rattus norvegicus 46020 R-SCE-434650 https://reactome.org/PathwayBrowser/#/R-SCE-434650 MATEs mediate extrusion of xenobiotics IEA Saccharomyces cerevisiae 46020 R-SPO-434650 https://reactome.org/PathwayBrowser/#/R-SPO-434650 MATEs mediate extrusion of xenobiotics IEA Schizosaccharomyces pombe 46020 R-SSC-434650 https://reactome.org/PathwayBrowser/#/R-SSC-434650 MATEs mediate extrusion of xenobiotics IEA Sus scrofa 46020 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 46020 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 46020 R-SSC-549304 https://reactome.org/PathwayBrowser/#/R-SSC-549304 OCT3 mediates renal clearance of organic cations IEA Sus scrofa 46020 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 46020 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 46020 R-SSC-561072 https://reactome.org/PathwayBrowser/#/R-SSC-561072 OCT3 mediates renal uptake of organic cations IEA Sus scrofa 46020 R-XTR-434650 https://reactome.org/PathwayBrowser/#/R-XTR-434650 MATEs mediate extrusion of xenobiotics IEA Xenopus tropicalis 46020 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 46020 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 46020 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 46020 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 46044 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 46044 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 46044 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 4610 R-HSA-2408541 https://reactome.org/PathwayBrowser/#/R-HSA-2408541 MeSeH is methylated to Me2Se by MeSeH methyltransferase IEA Homo sapiens 4610 R-HSA-2408554 https://reactome.org/PathwayBrowser/#/R-HSA-2408554 Me2Se is methylated to Me3Se+ by INMT IEA Homo sapiens 4610 R-MMU-2408549 https://reactome.org/PathwayBrowser/#/R-MMU-2408549 Me2Se is methylated to Me3Se+ by Inmt TAS Mus musculus 4610 R-RNO-2408501 https://reactome.org/PathwayBrowser/#/R-RNO-2408501 MeSeH is methylated to Me2Se by MeSeH methyltransferase TAS Rattus norvegicus 46195 R-BTA-158468 https://reactome.org/PathwayBrowser/#/R-BTA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Bos taurus 46195 R-BTA-158546 https://reactome.org/PathwayBrowser/#/R-BTA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Bos taurus 46195 R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 46195 R-BTA-9677320 https://reactome.org/PathwayBrowser/#/R-BTA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Bos taurus 46195 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 46195 R-BTA-9753277 https://reactome.org/PathwayBrowser/#/R-BTA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Bos taurus 46195 R-BTA-9753285 https://reactome.org/PathwayBrowser/#/R-BTA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Bos taurus 46195 R-CEL-158546 https://reactome.org/PathwayBrowser/#/R-CEL-158546 UGTs glucuronate APAP to APAP-GlcA IEA Caenorhabditis elegans 46195 R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 46195 R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans 46195 R-CFA-158468 https://reactome.org/PathwayBrowser/#/R-CFA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Canis familiaris 46195 R-CFA-158546 https://reactome.org/PathwayBrowser/#/R-CFA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Canis familiaris 46195 R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 46195 R-CFA-9677320 https://reactome.org/PathwayBrowser/#/R-CFA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Canis familiaris 46195 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 46195 R-CFA-9753277 https://reactome.org/PathwayBrowser/#/R-CFA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Canis familiaris 46195 R-CFA-9753285 https://reactome.org/PathwayBrowser/#/R-CFA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Canis familiaris 46195 R-DDI-158546 https://reactome.org/PathwayBrowser/#/R-DDI-158546 UGTs glucuronate APAP to APAP-GlcA IEA Dictyostelium discoideum 46195 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 46195 R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 46195 R-DDI-9753285 https://reactome.org/PathwayBrowser/#/R-DDI-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Dictyostelium discoideum 46195 R-DME-158468 https://reactome.org/PathwayBrowser/#/R-DME-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Drosophila melanogaster 46195 R-DME-158546 https://reactome.org/PathwayBrowser/#/R-DME-158546 UGTs glucuronate APAP to APAP-GlcA IEA Drosophila melanogaster 46195 R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 46195 R-DME-9753277 https://reactome.org/PathwayBrowser/#/R-DME-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Drosophila melanogaster 46195 R-DME-9753285 https://reactome.org/PathwayBrowser/#/R-DME-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Drosophila melanogaster 46195 R-DRE-158468 https://reactome.org/PathwayBrowser/#/R-DRE-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Danio rerio 46195 R-DRE-158546 https://reactome.org/PathwayBrowser/#/R-DRE-158546 UGTs glucuronate APAP to APAP-GlcA IEA Danio rerio 46195 R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 46195 R-DRE-9677320 https://reactome.org/PathwayBrowser/#/R-DRE-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Danio rerio 46195 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 46195 R-DRE-9753277 https://reactome.org/PathwayBrowser/#/R-DRE-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Danio rerio 46195 R-DRE-9753285 https://reactome.org/PathwayBrowser/#/R-DRE-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Danio rerio 46195 R-GGA-158468 https://reactome.org/PathwayBrowser/#/R-GGA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Gallus gallus 46195 R-GGA-158546 https://reactome.org/PathwayBrowser/#/R-GGA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Gallus gallus 46195 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 46195 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 46195 R-GGA-9677320 https://reactome.org/PathwayBrowser/#/R-GGA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Gallus gallus 46195 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 46195 R-GGA-9753277 https://reactome.org/PathwayBrowser/#/R-GGA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Gallus gallus 46195 R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus 46195 R-HSA-158468 https://reactome.org/PathwayBrowser/#/R-HSA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 TAS Homo sapiens 46195 R-HSA-158546 https://reactome.org/PathwayBrowser/#/R-HSA-158546 UGTs glucuronate APAP to APAP-GlcA TAS Homo sapiens 46195 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 46195 R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 46195 R-HSA-9677320 https://reactome.org/PathwayBrowser/#/R-HSA-9677320 PTGS1 dimer binds PTGS1 Inhibitors TAS Homo sapiens 46195 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 46195 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 46195 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 46195 R-HSA-9753277 https://reactome.org/PathwayBrowser/#/R-HSA-9753277 SULT dimers sulfate APAP to APAP-SO3 TAS Homo sapiens 46195 R-HSA-9753285 https://reactome.org/PathwayBrowser/#/R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI TAS Homo sapiens 46195 R-HSA-9754180 https://reactome.org/PathwayBrowser/#/R-HSA-9754180 APAP translocates from extracellular region to cytosol TAS Homo sapiens 46195 R-MMU-158468 https://reactome.org/PathwayBrowser/#/R-MMU-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Mus musculus 46195 R-MMU-158546 https://reactome.org/PathwayBrowser/#/R-MMU-158546 UGTs glucuronate APAP to APAP-GlcA IEA Mus musculus 46195 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 46195 R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 46195 R-MMU-9677320 https://reactome.org/PathwayBrowser/#/R-MMU-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Mus musculus 46195 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 46195 R-MMU-9753277 https://reactome.org/PathwayBrowser/#/R-MMU-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Mus musculus 46195 R-MMU-9753285 https://reactome.org/PathwayBrowser/#/R-MMU-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Mus musculus 46195 R-RNO-158468 https://reactome.org/PathwayBrowser/#/R-RNO-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Rattus norvegicus 46195 R-RNO-158546 https://reactome.org/PathwayBrowser/#/R-RNO-158546 UGTs glucuronate APAP to APAP-GlcA IEA Rattus norvegicus 46195 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 46195 R-RNO-76397 https://reactome.org/PathwayBrowser/#/R-RNO-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Rattus norvegicus 46195 R-RNO-9677320 https://reactome.org/PathwayBrowser/#/R-RNO-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Rattus norvegicus 46195 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 46195 R-RNO-9753277 https://reactome.org/PathwayBrowser/#/R-RNO-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Rattus norvegicus 46195 R-RNO-9753285 https://reactome.org/PathwayBrowser/#/R-RNO-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Rattus norvegicus 46195 R-SSC-158468 https://reactome.org/PathwayBrowser/#/R-SSC-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Sus scrofa 46195 R-SSC-158546 https://reactome.org/PathwayBrowser/#/R-SSC-158546 UGTs glucuronate APAP to APAP-GlcA IEA Sus scrofa 46195 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa 46195 R-SSC-9677320 https://reactome.org/PathwayBrowser/#/R-SSC-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Sus scrofa 46195 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 46195 R-SSC-9753277 https://reactome.org/PathwayBrowser/#/R-SSC-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Sus scrofa 46195 R-SSC-9753285 https://reactome.org/PathwayBrowser/#/R-SSC-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Sus scrofa 46195 R-XTR-158468 https://reactome.org/PathwayBrowser/#/R-XTR-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Xenopus tropicalis 46195 R-XTR-76397 https://reactome.org/PathwayBrowser/#/R-XTR-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Xenopus tropicalis 46195 R-XTR-9677320 https://reactome.org/PathwayBrowser/#/R-XTR-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Xenopus tropicalis 46195 R-XTR-9753277 https://reactome.org/PathwayBrowser/#/R-XTR-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Xenopus tropicalis 46195 R-XTR-9753285 https://reactome.org/PathwayBrowser/#/R-XTR-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Xenopus tropicalis 46202 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 46202 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 46202 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 46202 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 46202 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 46202 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 46202 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 46202 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 46202 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 46245 R-AMA-1614571 https://reactome.org/PathwayBrowser/#/R-AMA-1614571 Sqr oxidizes sulfide to bound persulfide TAS Arenicola marina 46245 R-BTA-163217 https://reactome.org/PathwayBrowser/#/R-BTA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Bos taurus 46245 R-BTA-164651 https://reactome.org/PathwayBrowser/#/R-BTA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Bos taurus 46245 R-BTA-70994 https://reactome.org/PathwayBrowser/#/R-BTA-70994 SDH complex dehydrogenates succinate IEA Bos taurus 46245 R-BTA-73569 https://reactome.org/PathwayBrowser/#/R-BTA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Bos taurus 46245 R-CEL-164651 https://reactome.org/PathwayBrowser/#/R-CEL-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Caenorhabditis elegans 46245 R-CEL-169270 https://reactome.org/PathwayBrowser/#/R-CEL-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Caenorhabditis elegans 46245 R-CEL-70994 https://reactome.org/PathwayBrowser/#/R-CEL-70994 SDH complex dehydrogenates succinate IEA Caenorhabditis elegans 46245 R-CEL-73569 https://reactome.org/PathwayBrowser/#/R-CEL-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Caenorhabditis elegans 46245 R-CFA-163217 https://reactome.org/PathwayBrowser/#/R-CFA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Canis familiaris 46245 R-CFA-169270 https://reactome.org/PathwayBrowser/#/R-CFA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Canis familiaris 46245 R-CFA-70994 https://reactome.org/PathwayBrowser/#/R-CFA-70994 SDH complex dehydrogenates succinate IEA Canis familiaris 46245 R-CFA-73569 https://reactome.org/PathwayBrowser/#/R-CFA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Canis familiaris 46245 R-DDI-164651 https://reactome.org/PathwayBrowser/#/R-DDI-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Dictyostelium discoideum 46245 R-DDI-169270 https://reactome.org/PathwayBrowser/#/R-DDI-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Dictyostelium discoideum 46245 R-DDI-70994 https://reactome.org/PathwayBrowser/#/R-DDI-70994 SDH complex dehydrogenates succinate IEA Dictyostelium discoideum 46245 R-DME-163217 https://reactome.org/PathwayBrowser/#/R-DME-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Drosophila melanogaster 46245 R-DME-164651 https://reactome.org/PathwayBrowser/#/R-DME-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Drosophila melanogaster 46245 R-DME-169270 https://reactome.org/PathwayBrowser/#/R-DME-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Drosophila melanogaster 46245 R-DME-70994 https://reactome.org/PathwayBrowser/#/R-DME-70994 SDH complex dehydrogenates succinate IEA Drosophila melanogaster 46245 R-DME-73569 https://reactome.org/PathwayBrowser/#/R-DME-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Drosophila melanogaster 46245 R-DRE-163217 https://reactome.org/PathwayBrowser/#/R-DRE-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Danio rerio 46245 R-DRE-164651 https://reactome.org/PathwayBrowser/#/R-DRE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Danio rerio 46245 R-DRE-169270 https://reactome.org/PathwayBrowser/#/R-DRE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Danio rerio 46245 R-DRE-70994 https://reactome.org/PathwayBrowser/#/R-DRE-70994 SDH complex dehydrogenates succinate IEA Danio rerio 46245 R-DRE-73569 https://reactome.org/PathwayBrowser/#/R-DRE-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Danio rerio 46245 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Gallus gallus 46245 R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus 46245 R-GGA-419452 https://reactome.org/PathwayBrowser/#/R-GGA-419452 (S)-dihydroorotate + ubiquinone => orotate + ubiquinol IEA Gallus gallus 46245 R-GGA-70994 https://reactome.org/PathwayBrowser/#/R-GGA-70994 SDH complex dehydrogenates succinate IEA Gallus gallus 46245 R-GGA-73569 https://reactome.org/PathwayBrowser/#/R-GGA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Gallus gallus 46245 R-HSA-1614665 https://reactome.org/PathwayBrowser/#/R-HSA-1614665 SQR oxidizes sulfide to bound persulfide IEA Homo sapiens 46245 R-HSA-163213 https://reactome.org/PathwayBrowser/#/R-HSA-163213 Transfer of electrons through the succinate dehydrogenase complex IEA Homo sapiens 46245 R-HSA-163217 https://reactome.org/PathwayBrowser/#/R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 TAS Homo sapiens 46245 R-HSA-164651 https://reactome.org/PathwayBrowser/#/R-HSA-164651 Electron transfer from ubiquinol to cytochrome c of complex III TAS Homo sapiens 46245 R-HSA-169270 https://reactome.org/PathwayBrowser/#/R-HSA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 TAS Homo sapiens 46245 R-HSA-70994 https://reactome.org/PathwayBrowser/#/R-HSA-70994 SDH complex dehydrogenates succinate TAS Homo sapiens 46245 R-HSA-73569 https://reactome.org/PathwayBrowser/#/R-HSA-73569 DHODH:FMN oxidises (S)-DHO to orotate TAS Homo sapiens 46245 R-MMU-163217 https://reactome.org/PathwayBrowser/#/R-MMU-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Mus musculus 46245 R-MMU-164651 https://reactome.org/PathwayBrowser/#/R-MMU-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Mus musculus 46245 R-MMU-169270 https://reactome.org/PathwayBrowser/#/R-MMU-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Mus musculus 46245 R-MMU-70994 https://reactome.org/PathwayBrowser/#/R-MMU-70994 SDH complex dehydrogenates succinate IEA Mus musculus 46245 R-MMU-73569 https://reactome.org/PathwayBrowser/#/R-MMU-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Mus musculus 46245 R-PFA-73569 https://reactome.org/PathwayBrowser/#/R-PFA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Plasmodium falciparum 46245 R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Rattus norvegicus 46245 R-RNO-164651 https://reactome.org/PathwayBrowser/#/R-RNO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Rattus norvegicus 46245 R-RNO-169270 https://reactome.org/PathwayBrowser/#/R-RNO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Rattus norvegicus 46245 R-RNO-70994 https://reactome.org/PathwayBrowser/#/R-RNO-70994 SDH complex dehydrogenates succinate IEA Rattus norvegicus 46245 R-RNO-73569 https://reactome.org/PathwayBrowser/#/R-RNO-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Rattus norvegicus 46245 R-SCE-164651 https://reactome.org/PathwayBrowser/#/R-SCE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Saccharomyces cerevisiae 46245 R-SCE-169270 https://reactome.org/PathwayBrowser/#/R-SCE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Saccharomyces cerevisiae 46245 R-SCE-70994 https://reactome.org/PathwayBrowser/#/R-SCE-70994 SDH complex dehydrogenates succinate IEA Saccharomyces cerevisiae 46245 R-SPO-164651 https://reactome.org/PathwayBrowser/#/R-SPO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Schizosaccharomyces pombe 46245 R-SPO-169270 https://reactome.org/PathwayBrowser/#/R-SPO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Schizosaccharomyces pombe 46245 R-SPO-70994 https://reactome.org/PathwayBrowser/#/R-SPO-70994 SDH complex dehydrogenates succinate IEA Schizosaccharomyces pombe 46245 R-SPO-73569 https://reactome.org/PathwayBrowser/#/R-SPO-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Schizosaccharomyces pombe 46245 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Sus scrofa 46245 R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa 46245 R-SSC-169270 https://reactome.org/PathwayBrowser/#/R-SSC-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Sus scrofa 46245 R-SSC-70994 https://reactome.org/PathwayBrowser/#/R-SSC-70994 SDH complex dehydrogenates succinate IEA Sus scrofa 46245 R-SSC-73569 https://reactome.org/PathwayBrowser/#/R-SSC-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Sus scrofa 46245 R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Xenopus tropicalis 46245 R-XTR-169270 https://reactome.org/PathwayBrowser/#/R-XTR-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Xenopus tropicalis 46245 R-XTR-70994 https://reactome.org/PathwayBrowser/#/R-XTR-70994 SDH complex dehydrogenates succinate IEA Xenopus tropicalis 46245 R-XTR-73569 https://reactome.org/PathwayBrowser/#/R-XTR-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Xenopus tropicalis 46261 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 46261 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 46261 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 46261 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 46261 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 46261 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 46261 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 46261 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 46261 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 46261 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 4638 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 4638 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 4638 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 4638 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 4638 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 4638 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 4638 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 4638 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 4638 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 4638 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 46398 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 46398 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 46398 R-BTA-417898 https://reactome.org/PathwayBrowser/#/R-BTA-417898 P2Y4 receptor can bind to UTP IEA Bos taurus 46398 R-BTA-417927 https://reactome.org/PathwayBrowser/#/R-BTA-417927 P2Y2 receptor binds ATP and UTP IEA Bos taurus 46398 R-BTA-446204 https://reactome.org/PathwayBrowser/#/R-BTA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Bos taurus 46398 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 46398 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 46398 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 46398 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 46398 R-BTA-504054 https://reactome.org/PathwayBrowser/#/R-BTA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Bos taurus 46398 R-BTA-5684862 https://reactome.org/PathwayBrowser/#/R-BTA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Bos taurus 46398 R-BTA-6814549 https://reactome.org/PathwayBrowser/#/R-BTA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Bos taurus 46398 R-BTA-6814559 https://reactome.org/PathwayBrowser/#/R-BTA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Bos taurus 46398 R-BTA-70286 https://reactome.org/PathwayBrowser/#/R-BTA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Bos taurus 46398 R-BTA-73647 https://reactome.org/PathwayBrowser/#/R-BTA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Bos taurus 46398 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 46398 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 46398 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 46398 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 46398 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 46398 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 46398 R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 46398 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 46398 R-CEL-446204 https://reactome.org/PathwayBrowser/#/R-CEL-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Caenorhabditis elegans 46398 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 46398 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 46398 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 46398 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 46398 R-CEL-504054 https://reactome.org/PathwayBrowser/#/R-CEL-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Caenorhabditis elegans 46398 R-CEL-6814559 https://reactome.org/PathwayBrowser/#/R-CEL-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Caenorhabditis elegans 46398 R-CEL-70286 https://reactome.org/PathwayBrowser/#/R-CEL-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Caenorhabditis elegans 46398 R-CEL-73647 https://reactome.org/PathwayBrowser/#/R-CEL-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Caenorhabditis elegans 46398 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 46398 R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 46398 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 46398 R-CFA-417927 https://reactome.org/PathwayBrowser/#/R-CFA-417927 P2Y2 receptor binds ATP and UTP IEA Canis familiaris 46398 R-CFA-446204 https://reactome.org/PathwayBrowser/#/R-CFA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Canis familiaris 46398 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 46398 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 46398 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 46398 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 46398 R-CFA-504054 https://reactome.org/PathwayBrowser/#/R-CFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Canis familiaris 46398 R-CFA-5684862 https://reactome.org/PathwayBrowser/#/R-CFA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Canis familiaris 46398 R-CFA-6814549 https://reactome.org/PathwayBrowser/#/R-CFA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Canis familiaris 46398 R-CFA-6814559 https://reactome.org/PathwayBrowser/#/R-CFA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Canis familiaris 46398 R-CFA-70286 https://reactome.org/PathwayBrowser/#/R-CFA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Canis familiaris 46398 R-CFA-73647 https://reactome.org/PathwayBrowser/#/R-CFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Canis familiaris 46398 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 46398 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 46398 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 46398 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 46398 R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 46398 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 46398 R-DDI-446204 https://reactome.org/PathwayBrowser/#/R-DDI-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Dictyostelium discoideum 46398 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 46398 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 46398 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 46398 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 46398 R-DDI-504054 https://reactome.org/PathwayBrowser/#/R-DDI-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Dictyostelium discoideum 46398 R-DDI-6814559 https://reactome.org/PathwayBrowser/#/R-DDI-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Dictyostelium discoideum 46398 R-DDI-70286 https://reactome.org/PathwayBrowser/#/R-DDI-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Dictyostelium discoideum 46398 R-DDI-73647 https://reactome.org/PathwayBrowser/#/R-DDI-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Dictyostelium discoideum 46398 R-DME-446204 https://reactome.org/PathwayBrowser/#/R-DME-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Drosophila melanogaster 46398 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 46398 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 46398 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 46398 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 46398 R-DME-504054 https://reactome.org/PathwayBrowser/#/R-DME-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Drosophila melanogaster 46398 R-DME-6814549 https://reactome.org/PathwayBrowser/#/R-DME-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Drosophila melanogaster 46398 R-DME-6814559 https://reactome.org/PathwayBrowser/#/R-DME-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Drosophila melanogaster 46398 R-DME-70286 https://reactome.org/PathwayBrowser/#/R-DME-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Drosophila melanogaster 46398 R-DME-73647 https://reactome.org/PathwayBrowser/#/R-DME-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Drosophila melanogaster 46398 R-DRE-446204 https://reactome.org/PathwayBrowser/#/R-DRE-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Danio rerio 46398 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 46398 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 46398 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 46398 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 46398 R-DRE-504054 https://reactome.org/PathwayBrowser/#/R-DRE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Danio rerio 46398 R-DRE-6814559 https://reactome.org/PathwayBrowser/#/R-DRE-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Danio rerio 46398 R-DRE-73647 https://reactome.org/PathwayBrowser/#/R-DRE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Danio rerio 46398 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 46398 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 46398 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 46398 R-GGA-417898 https://reactome.org/PathwayBrowser/#/R-GGA-417898 P2Y4 receptor can bind to UTP IEA Gallus gallus 46398 R-GGA-446204 https://reactome.org/PathwayBrowser/#/R-GGA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Gallus gallus 46398 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 46398 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 46398 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 46398 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 46398 R-GGA-504054 https://reactome.org/PathwayBrowser/#/R-GGA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Gallus gallus 46398 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus 46398 R-GGA-70286 https://reactome.org/PathwayBrowser/#/R-GGA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Gallus gallus 46398 R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus 46398 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 46398 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 46398 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 46398 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 46398 R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 46398 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 46398 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 46398 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 46398 R-HSA-417898 https://reactome.org/PathwayBrowser/#/R-HSA-417898 P2Y4 receptor can bind to UTP TAS Homo sapiens 46398 R-HSA-417927 https://reactome.org/PathwayBrowser/#/R-HSA-417927 P2Y2 receptor binds ATP and UTP TAS Homo sapiens 46398 R-HSA-446204 https://reactome.org/PathwayBrowser/#/R-HSA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine TAS Homo sapiens 46398 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 46398 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 46398 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 46398 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 46398 R-HSA-504054 https://reactome.org/PathwayBrowser/#/R-HSA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] TAS Homo sapiens 46398 R-HSA-5684862 https://reactome.org/PathwayBrowser/#/R-HSA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. TAS Homo sapiens 46398 R-HSA-6814549 https://reactome.org/PathwayBrowser/#/R-HSA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding TAS Homo sapiens 46398 R-HSA-6814559 https://reactome.org/PathwayBrowser/#/R-HSA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine TAS Homo sapiens 46398 R-HSA-70286 https://reactome.org/PathwayBrowser/#/R-HSA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose TAS Homo sapiens 46398 R-HSA-73647 https://reactome.org/PathwayBrowser/#/R-HSA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] TAS Homo sapiens 46398 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 46398 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 46398 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 46398 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 46398 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 46398 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 46398 R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 46398 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 46398 R-HSA-8941312 https://reactome.org/PathwayBrowser/#/R-HSA-8941312 TUT4,TUT7 oligouridylate mRNA IEA Homo sapiens 46398 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 46398 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 46398 R-MMU-417898 https://reactome.org/PathwayBrowser/#/R-MMU-417898 P2Y4 receptor can bind to UTP IEA Mus musculus 46398 R-MMU-417927 https://reactome.org/PathwayBrowser/#/R-MMU-417927 P2Y2 receptor binds ATP and UTP IEA Mus musculus 46398 R-MMU-446204 https://reactome.org/PathwayBrowser/#/R-MMU-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Mus musculus 46398 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 46398 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 46398 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 46398 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 46398 R-MMU-504054 https://reactome.org/PathwayBrowser/#/R-MMU-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Mus musculus 46398 R-MMU-5684862 https://reactome.org/PathwayBrowser/#/R-MMU-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Mus musculus 46398 R-MMU-6814549 https://reactome.org/PathwayBrowser/#/R-MMU-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Mus musculus 46398 R-MMU-6814559 https://reactome.org/PathwayBrowser/#/R-MMU-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Mus musculus 46398 R-MMU-70286 https://reactome.org/PathwayBrowser/#/R-MMU-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Mus musculus 46398 R-MMU-73647 https://reactome.org/PathwayBrowser/#/R-MMU-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Mus musculus 46398 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 46398 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 46398 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 46398 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 46398 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 46398 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 46398 R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 46398 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 46398 R-MMU-9820884 https://reactome.org/PathwayBrowser/#/R-MMU-9820884 Tut4,Tut7 oligouridylate mRNA TAS Mus musculus 46398 R-PFA-446204 https://reactome.org/PathwayBrowser/#/R-PFA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Plasmodium falciparum 46398 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 46398 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 46398 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 46398 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 46398 R-PFA-504054 https://reactome.org/PathwayBrowser/#/R-PFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Plasmodium falciparum 46398 R-PFA-73647 https://reactome.org/PathwayBrowser/#/R-PFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Plasmodium falciparum 46398 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 46398 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 46398 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 46398 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 46398 R-RNO-417898 https://reactome.org/PathwayBrowser/#/R-RNO-417898 P2Y4 receptor can bind to UTP IEA Rattus norvegicus 46398 R-RNO-417927 https://reactome.org/PathwayBrowser/#/R-RNO-417927 P2Y2 receptor binds ATP and UTP IEA Rattus norvegicus 46398 R-RNO-446204 https://reactome.org/PathwayBrowser/#/R-RNO-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Rattus norvegicus 46398 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 46398 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 46398 R-RNO-504054 https://reactome.org/PathwayBrowser/#/R-RNO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Rattus norvegicus 46398 R-RNO-5684862 https://reactome.org/PathwayBrowser/#/R-RNO-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Rattus norvegicus 46398 R-RNO-6814549 https://reactome.org/PathwayBrowser/#/R-RNO-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Rattus norvegicus 46398 R-RNO-6814559 https://reactome.org/PathwayBrowser/#/R-RNO-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Rattus norvegicus 46398 R-RNO-70286 https://reactome.org/PathwayBrowser/#/R-RNO-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Rattus norvegicus 46398 R-RNO-73647 https://reactome.org/PathwayBrowser/#/R-RNO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Rattus norvegicus 46398 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 46398 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 46398 R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 46398 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 46398 R-SCE-446204 https://reactome.org/PathwayBrowser/#/R-SCE-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Saccharomyces cerevisiae 46398 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 46398 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 46398 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 46398 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 46398 R-SCE-504054 https://reactome.org/PathwayBrowser/#/R-SCE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Saccharomyces cerevisiae 46398 R-SCE-70286 https://reactome.org/PathwayBrowser/#/R-SCE-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Saccharomyces cerevisiae 46398 R-SCE-73647 https://reactome.org/PathwayBrowser/#/R-SCE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Saccharomyces cerevisiae 46398 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 46398 R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 46398 R-SPO-446204 https://reactome.org/PathwayBrowser/#/R-SPO-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Schizosaccharomyces pombe 46398 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 46398 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 46398 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 46398 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 46398 R-SPO-504054 https://reactome.org/PathwayBrowser/#/R-SPO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Schizosaccharomyces pombe 46398 R-SPO-70286 https://reactome.org/PathwayBrowser/#/R-SPO-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Schizosaccharomyces pombe 46398 R-SPO-73647 https://reactome.org/PathwayBrowser/#/R-SPO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Schizosaccharomyces pombe 46398 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 46398 R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 46398 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 46398 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 46398 R-SSC-417898 https://reactome.org/PathwayBrowser/#/R-SSC-417898 P2Y4 receptor can bind to UTP IEA Sus scrofa 46398 R-SSC-417927 https://reactome.org/PathwayBrowser/#/R-SSC-417927 P2Y2 receptor binds ATP and UTP IEA Sus scrofa 46398 R-SSC-446204 https://reactome.org/PathwayBrowser/#/R-SSC-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Sus scrofa 46398 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 46398 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 46398 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 46398 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 46398 R-SSC-504054 https://reactome.org/PathwayBrowser/#/R-SSC-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Sus scrofa 46398 R-SSC-5684862 https://reactome.org/PathwayBrowser/#/R-SSC-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Sus scrofa 46398 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa 46398 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa 46398 R-SSC-70286 https://reactome.org/PathwayBrowser/#/R-SSC-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Sus scrofa 46398 R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa 46398 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 46398 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 46398 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 46398 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 46398 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 46398 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 46398 R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 46398 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 46398 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 46398 R-XTR-417898 https://reactome.org/PathwayBrowser/#/R-XTR-417898 P2Y4 receptor can bind to UTP IEA Xenopus tropicalis 46398 R-XTR-417927 https://reactome.org/PathwayBrowser/#/R-XTR-417927 P2Y2 receptor binds ATP and UTP IEA Xenopus tropicalis 46398 R-XTR-446204 https://reactome.org/PathwayBrowser/#/R-XTR-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Xenopus tropicalis 46398 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 46398 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 46398 R-XTR-6814559 https://reactome.org/PathwayBrowser/#/R-XTR-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Xenopus tropicalis 46398 R-XTR-70286 https://reactome.org/PathwayBrowser/#/R-XTR-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Xenopus tropicalis 46398 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 46398 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 46398 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 46398 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 46398 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 46398 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 46398 R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 46398 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 46557 R-CEL-9717841 https://reactome.org/PathwayBrowser/#/R-CEL-9717841 holo-FDPS dimer binds NBPs IEA Caenorhabditis elegans 46557 R-CFA-9717841 https://reactome.org/PathwayBrowser/#/R-CFA-9717841 holo-FDPS dimer binds NBPs IEA Canis familiaris 46557 R-DDI-9717841 https://reactome.org/PathwayBrowser/#/R-DDI-9717841 holo-FDPS dimer binds NBPs IEA Dictyostelium discoideum 46557 R-DME-9717841 https://reactome.org/PathwayBrowser/#/R-DME-9717841 holo-FDPS dimer binds NBPs IEA Drosophila melanogaster 46557 R-DRE-9717841 https://reactome.org/PathwayBrowser/#/R-DRE-9717841 holo-FDPS dimer binds NBPs IEA Danio rerio 46557 R-GGA-9717841 https://reactome.org/PathwayBrowser/#/R-GGA-9717841 holo-FDPS dimer binds NBPs IEA Gallus gallus 46557 R-HSA-9717841 https://reactome.org/PathwayBrowser/#/R-HSA-9717841 holo-FDPS dimer binds NBPs TAS Homo sapiens 46557 R-MMU-9717841 https://reactome.org/PathwayBrowser/#/R-MMU-9717841 holo-FDPS dimer binds NBPs IEA Mus musculus 46557 R-PFA-9717841 https://reactome.org/PathwayBrowser/#/R-PFA-9717841 holo-FDPS dimer binds NBPs IEA Plasmodium falciparum 46557 R-RNO-9717841 https://reactome.org/PathwayBrowser/#/R-RNO-9717841 holo-FDPS dimer binds NBPs IEA Rattus norvegicus 46557 R-SCE-9717841 https://reactome.org/PathwayBrowser/#/R-SCE-9717841 holo-FDPS dimer binds NBPs IEA Saccharomyces cerevisiae 46557 R-SPO-9717841 https://reactome.org/PathwayBrowser/#/R-SPO-9717841 holo-FDPS dimer binds NBPs IEA Schizosaccharomyces pombe 46557 R-SSC-9717841 https://reactome.org/PathwayBrowser/#/R-SSC-9717841 holo-FDPS dimer binds NBPs IEA Sus scrofa 4659 R-BTA-9693324 https://reactome.org/PathwayBrowser/#/R-BTA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Bos taurus 4659 R-CFA-9693324 https://reactome.org/PathwayBrowser/#/R-CFA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Canis familiaris 4659 R-GGA-9693324 https://reactome.org/PathwayBrowser/#/R-GGA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Gallus gallus 4659 R-HSA-9693324 https://reactome.org/PathwayBrowser/#/R-HSA-9693324 Disulfiram covalently modifies Cys191 in GSDMD TAS Homo sapiens 4659 R-MMU-9693324 https://reactome.org/PathwayBrowser/#/R-MMU-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Mus musculus 4659 R-RNO-9693324 https://reactome.org/PathwayBrowser/#/R-RNO-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Rattus norvegicus 4659 R-SSC-9693324 https://reactome.org/PathwayBrowser/#/R-SSC-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Sus scrofa 46631 R-BTA-549304 https://reactome.org/PathwayBrowser/#/R-BTA-549304 OCT3 mediates renal clearance of organic cations IEA Bos taurus 46631 R-BTA-561072 https://reactome.org/PathwayBrowser/#/R-BTA-561072 OCT3 mediates renal uptake of organic cations IEA Bos taurus 46631 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 46631 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans 46631 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans 46631 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 46631 R-CFA-549304 https://reactome.org/PathwayBrowser/#/R-CFA-549304 OCT3 mediates renal clearance of organic cations IEA Canis familiaris 46631 R-CFA-561072 https://reactome.org/PathwayBrowser/#/R-CFA-561072 OCT3 mediates renal uptake of organic cations IEA Canis familiaris 46631 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 46631 R-DME-549304 https://reactome.org/PathwayBrowser/#/R-DME-549304 OCT3 mediates renal clearance of organic cations IEA Drosophila melanogaster 46631 R-DME-561072 https://reactome.org/PathwayBrowser/#/R-DME-561072 OCT3 mediates renal uptake of organic cations IEA Drosophila melanogaster 46631 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 46631 R-DRE-549304 https://reactome.org/PathwayBrowser/#/R-DRE-549304 OCT3 mediates renal clearance of organic cations IEA Danio rerio 46631 R-DRE-561072 https://reactome.org/PathwayBrowser/#/R-DRE-561072 OCT3 mediates renal uptake of organic cations IEA Danio rerio 46631 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 46631 R-GGA-549304 https://reactome.org/PathwayBrowser/#/R-GGA-549304 OCT3 mediates renal clearance of organic cations IEA Gallus gallus 46631 R-GGA-561072 https://reactome.org/PathwayBrowser/#/R-GGA-561072 OCT3 mediates renal uptake of organic cations IEA Gallus gallus 46631 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 46631 R-HSA-549304 https://reactome.org/PathwayBrowser/#/R-HSA-549304 OCT3 mediates renal clearance of organic cations TAS Homo sapiens 46631 R-HSA-561072 https://reactome.org/PathwayBrowser/#/R-HSA-561072 OCT3 mediates renal uptake of organic cations TAS Homo sapiens 46631 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 46631 R-MMU-549304 https://reactome.org/PathwayBrowser/#/R-MMU-549304 OCT3 mediates renal clearance of organic cations IEA Mus musculus 46631 R-MMU-561072 https://reactome.org/PathwayBrowser/#/R-MMU-561072 OCT3 mediates renal uptake of organic cations IEA Mus musculus 46631 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 46631 R-RNO-549304 https://reactome.org/PathwayBrowser/#/R-RNO-549304 OCT3 mediates renal clearance of organic cations IEA Rattus norvegicus 46631 R-RNO-561072 https://reactome.org/PathwayBrowser/#/R-RNO-561072 OCT3 mediates renal uptake of organic cations IEA Rattus norvegicus 46631 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 46631 R-SSC-549304 https://reactome.org/PathwayBrowser/#/R-SSC-549304 OCT3 mediates renal clearance of organic cations IEA Sus scrofa 46631 R-SSC-561072 https://reactome.org/PathwayBrowser/#/R-SSC-561072 OCT3 mediates renal uptake of organic cations IEA Sus scrofa 46631 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 46631 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 46640 R-BTA-6786190 https://reactome.org/PathwayBrowser/#/R-BTA-6786190 CMBL hydrolyses OM to OLMS IEA Bos taurus 46640 R-CFA-6786190 https://reactome.org/PathwayBrowser/#/R-CFA-6786190 CMBL hydrolyses OM to OLMS IEA Canis familiaris 46640 R-DRE-6786190 https://reactome.org/PathwayBrowser/#/R-DRE-6786190 CMBL hydrolyses OM to OLMS IEA Danio rerio 46640 R-GGA-6786190 https://reactome.org/PathwayBrowser/#/R-GGA-6786190 CMBL hydrolyses OM to OLMS IEA Gallus gallus 46640 R-HSA-6786190 https://reactome.org/PathwayBrowser/#/R-HSA-6786190 CMBL hydrolyses OM to OLMS TAS Homo sapiens 46640 R-MMU-6786190 https://reactome.org/PathwayBrowser/#/R-MMU-6786190 CMBL hydrolyses OM to OLMS IEA Mus musculus 46640 R-RNO-6786190 https://reactome.org/PathwayBrowser/#/R-RNO-6786190 CMBL hydrolyses OM to OLMS IEA Rattus norvegicus 46640 R-SSC-6786190 https://reactome.org/PathwayBrowser/#/R-SSC-6786190 CMBL hydrolyses OM to OLMS IEA Sus scrofa 46640 R-XTR-6786190 https://reactome.org/PathwayBrowser/#/R-XTR-6786190 CMBL hydrolyses OM to OLMS IEA Xenopus tropicalis 46661 R-BTA-1306876 https://reactome.org/PathwayBrowser/#/R-BTA-1306876 NLRP3 activation by small molecules IEA Bos taurus 46661 R-CFA-1306876 https://reactome.org/PathwayBrowser/#/R-CFA-1306876 NLRP3 activation by small molecules IEA Canis familiaris 46661 R-DRE-1306876 https://reactome.org/PathwayBrowser/#/R-DRE-1306876 NLRP3 activation by small molecules IEA Danio rerio 46661 R-GGA-1306876 https://reactome.org/PathwayBrowser/#/R-GGA-1306876 NLRP3 activation by small molecules IEA Gallus gallus 46661 R-HSA-1296421 https://reactome.org/PathwayBrowser/#/R-HSA-1296421 NLRP3 oligomerizes via NACHT domains TAS Homo sapiens 46661 R-HSA-1306876 https://reactome.org/PathwayBrowser/#/R-HSA-1306876 NLRP3 activation by small molecules TAS Homo sapiens 46661 R-HSA-844610 https://reactome.org/PathwayBrowser/#/R-HSA-844610 NLRP3 recruits PYCARD (ASC) via a PYD-PYD interaction TAS Homo sapiens 46661 R-HSA-844612 https://reactome.org/PathwayBrowser/#/R-HSA-844612 PYCARD recruits procaspase-1 via CARD TAS Homo sapiens 46661 R-MMU-1306876 https://reactome.org/PathwayBrowser/#/R-MMU-1306876 NLRP3 activation by small molecules IEA Mus musculus 46661 R-RNO-1306876 https://reactome.org/PathwayBrowser/#/R-RNO-1306876 NLRP3 activation by small molecules IEA Rattus norvegicus 46661 R-SSC-1306876 https://reactome.org/PathwayBrowser/#/R-SSC-1306876 NLRP3 activation by small molecules IEA Sus scrofa 46661 R-XTR-1306876 https://reactome.org/PathwayBrowser/#/R-XTR-1306876 NLRP3 activation by small molecules IEA Xenopus tropicalis 4670 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 4670 R-BTA-9611751 https://reactome.org/PathwayBrowser/#/R-BTA-9611751 β1,2-agonists bind ADRB1,2 IEA Bos taurus 4670 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 4670 R-CFA-9611751 https://reactome.org/PathwayBrowser/#/R-CFA-9611751 β1,2-agonists bind ADRB1,2 IEA Canis familiaris 4670 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 4670 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 4670 R-DME-9611751 https://reactome.org/PathwayBrowser/#/R-DME-9611751 β1,2-agonists bind ADRB1,2 IEA Drosophila melanogaster 4670 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 4670 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 4670 R-DRE-9611751 https://reactome.org/PathwayBrowser/#/R-DRE-9611751 β1,2-agonists bind ADRB1,2 IEA Danio rerio 4670 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 4670 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 4670 R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus 4670 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 4670 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 4670 R-HSA-9611751 https://reactome.org/PathwayBrowser/#/R-HSA-9611751 β1,2-agonists bind ADRB1,2 TAS Homo sapiens 4670 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 4670 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 4670 R-MMU-9611751 https://reactome.org/PathwayBrowser/#/R-MMU-9611751 β1,2-agonists bind ADRB1,2 IEA Mus musculus 4670 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 4670 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 4670 R-RNO-9611751 https://reactome.org/PathwayBrowser/#/R-RNO-9611751 β1,2-agonists bind ADRB1,2 IEA Rattus norvegicus 4670 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 4670 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 4670 R-SSC-9611751 https://reactome.org/PathwayBrowser/#/R-SSC-9611751 β1,2-agonists bind ADRB1,2 IEA Sus scrofa 4670 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 4670 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 4670 R-XTR-9611751 https://reactome.org/PathwayBrowser/#/R-XTR-9611751 β1,2-agonists bind ADRB1,2 IEA Xenopus tropicalis 4670 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 46761 R-BTA-428007 https://reactome.org/PathwayBrowser/#/R-BTA-428007 Proton-coupled histidine and di-peptide cotransport IEA Bos taurus 46761 R-CFA-428007 https://reactome.org/PathwayBrowser/#/R-CFA-428007 Proton-coupled histidine and di-peptide cotransport IEA Canis familiaris 46761 R-GGA-428007 https://reactome.org/PathwayBrowser/#/R-GGA-428007 Proton-coupled histidine and di-peptide cotransport IEA Gallus gallus 46761 R-HSA-428007 https://reactome.org/PathwayBrowser/#/R-HSA-428007 Proton-coupled histidine and di-peptide cotransport TAS Homo sapiens 46761 R-MMU-428007 https://reactome.org/PathwayBrowser/#/R-MMU-428007 Proton-coupled histidine and di-peptide cotransport IEA Mus musculus 46761 R-RNO-428007 https://reactome.org/PathwayBrowser/#/R-RNO-428007 Proton-coupled histidine and di-peptide cotransport IEA Rattus norvegicus 46761 R-SCE-428007 https://reactome.org/PathwayBrowser/#/R-SCE-428007 Proton-coupled histidine and di-peptide cotransport IEA Saccharomyces cerevisiae 46761 R-SPO-428007 https://reactome.org/PathwayBrowser/#/R-SPO-428007 Proton-coupled histidine and di-peptide cotransport IEA Schizosaccharomyces pombe 46761 R-SSC-428007 https://reactome.org/PathwayBrowser/#/R-SSC-428007 Proton-coupled histidine and di-peptide cotransport IEA Sus scrofa 46761 R-XTR-428007 https://reactome.org/PathwayBrowser/#/R-XTR-428007 Proton-coupled histidine and di-peptide cotransport IEA Xenopus tropicalis 46763 R-DME-209158 https://reactome.org/PathwayBrowser/#/R-DME-209158 Polymeric PGN bound PGRP-LCx multimerises at the plasma membrane TAS Drosophila melanogaster 46763 R-DME-209167 https://reactome.org/PathwayBrowser/#/R-DME-209167 Phosphorylated REL is cleaved by and dissociates from DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' TAS Drosophila melanogaster 46763 R-DME-209185 https://reactome.org/PathwayBrowser/#/R-DME-209185 Monomeric PGN bound PGRP-LCx heterodimerises with PGRP-LCa at the plasma membrane TAS Drosophila melanogaster 46763 R-DME-209221 https://reactome.org/PathwayBrowser/#/R-DME-209221 Assembly of the PGN:PGRP-LC oligomer receptor 'signalling complex' IEA Drosophila melanogaster 46763 R-DME-209227 https://reactome.org/PathwayBrowser/#/R-DME-209227 Activated Phospho IRD5:KEY dimer phosphorylates REL in the PGN:PGRP-LC oligomer receptor 'signalling complex' TAS Drosophila melanogaster 46763 R-DME-209244 https://reactome.org/PathwayBrowser/#/R-DME-209244 REL binds to DREDD in the PGN:PGRP-LC oligomer receptor 'signalling complex' TAS Drosophila melanogaster 46763 R-DME-209355 https://reactome.org/PathwayBrowser/#/R-DME-209355 Monomeric PGN binds to PGRP-LCx at the plasma membrane TAS Drosophila melanogaster 46763 R-DME-209377 https://reactome.org/PathwayBrowser/#/R-DME-209377 Polymeric PGN binds to PGRP-LCx at the plasma membrane TAS Drosophila melanogaster 46763 R-DME-214393 https://reactome.org/PathwayBrowser/#/R-DME-214393 Phosphorylated REL is cleaved by and dissociates from DREDD in the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' TAS Drosophila melanogaster 46763 R-DME-214395 https://reactome.org/PathwayBrowser/#/R-DME-214395 Monomeric PGN bound PGRP-LE oligomerises in the cytosol TAS Drosophila melanogaster 46763 R-DME-214398 https://reactome.org/PathwayBrowser/#/R-DME-214398 Activated Phospho IRD5:KEY dimer phosphorylates REL in the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' TAS Drosophila melanogaster 46763 R-DME-214405 https://reactome.org/PathwayBrowser/#/R-DME-214405 Assembly of the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' IEA Drosophila melanogaster 46763 R-DME-214410 https://reactome.org/PathwayBrowser/#/R-DME-214410 Monomeric PGN binds to PGRP-LE in the cytosol TAS Drosophila melanogaster 46763 R-DME-214418 https://reactome.org/PathwayBrowser/#/R-DME-214418 REL binds to monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' TAS Drosophila melanogaster 4681 R-BTA-9613264 https://reactome.org/PathwayBrowser/#/R-BTA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Bos taurus 4681 R-CFA-9613264 https://reactome.org/PathwayBrowser/#/R-CFA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Canis familiaris 4681 R-GGA-9613264 https://reactome.org/PathwayBrowser/#/R-GGA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Gallus gallus 4681 R-HSA-9613264 https://reactome.org/PathwayBrowser/#/R-HSA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE TAS Homo sapiens 4681 R-MMU-9613264 https://reactome.org/PathwayBrowser/#/R-MMU-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Mus musculus 4681 R-RNO-9613264 https://reactome.org/PathwayBrowser/#/R-RNO-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Rattus norvegicus 4681 R-SSC-9613264 https://reactome.org/PathwayBrowser/#/R-SSC-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Sus scrofa 46896 R-GGA-433864 https://reactome.org/PathwayBrowser/#/R-GGA-433864 IRAK2 binds to the IRAK4 accociated with the complex of the activated TLR : TIRAP : MyD88 IEA Gallus gallus 46896 R-GGA-433961 https://reactome.org/PathwayBrowser/#/R-GGA-433961 Activated TLR homo- or heterodimer recruits adaptors TIRAP(or MAL) and MyD88 IEA Gallus gallus 46896 R-GGA-434018 https://reactome.org/PathwayBrowser/#/R-GGA-434018 Autophosphorylation of chicken IRAK4 IEA Gallus gallus 46896 R-GGA-434047 https://reactome.org/PathwayBrowser/#/R-GGA-434047 phosphorylation of IRAK2 by activated IRAK4 IEA Gallus gallus 46896 R-GGA-434053 https://reactome.org/PathwayBrowser/#/R-GGA-434053 TRAF6 binds to p-IRAK2 complexed with activated TLR IEA Gallus gallus 46896 R-GGA-434073 https://reactome.org/PathwayBrowser/#/R-GGA-434073 IRAK4 recruitment to the activated TLR complexed with ligand, TIRAP and MyD88 IEA Gallus gallus 46896 R-GGA-434084 https://reactome.org/PathwayBrowser/#/R-GGA-434084 p-IRAK2- TRAF6 dissociates from the activated chTLR complex IEA Gallus gallus 46896 R-GGA-517850 https://reactome.org/PathwayBrowser/#/R-GGA-517850 TLR2-1 : TLR1-2 heterodimer binds to its ligand TAS Gallus gallus 46896 R-HSA-166072 https://reactome.org/PathwayBrowser/#/R-HSA-166072 MyD88 forms a complex with TIRAP:activated TLR2/4 TAS Homo sapiens 46896 R-HSA-166082 https://reactome.org/PathwayBrowser/#/R-HSA-166082 IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex TAS Homo sapiens 46896 R-HSA-166091 https://reactome.org/PathwayBrowser/#/R-HSA-166091 IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex TAS Homo sapiens 46896 R-HSA-166119 https://reactome.org/PathwayBrowser/#/R-HSA-166119 First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal TAS Homo sapiens 46896 R-HSA-166284 https://reactome.org/PathwayBrowser/#/R-HSA-166284 Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP TAS Homo sapiens 46896 R-HSA-166286 https://reactome.org/PathwayBrowser/#/R-HSA-166286 Multiple IRAK1 autophosphorylation steps TAS Homo sapiens 46896 R-HSA-166362 https://reactome.org/PathwayBrowser/#/R-HSA-166362 Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 46896 R-HSA-166363 https://reactome.org/PathwayBrowser/#/R-HSA-166363 TRAF6 binds to hp- IRAK1 TAS Homo sapiens 46896 R-HSA-168950 https://reactome.org/PathwayBrowser/#/R-HSA-168950 TLR6:TLR2 is recruited to ligand:CD14:CD36 TAS Homo sapiens 46896 R-HSA-2201316 https://reactome.org/PathwayBrowser/#/R-HSA-2201316 Activated TLR2/4 interacts with MAL (TIRAP) TAS Homo sapiens 46896 R-HSA-2201322 https://reactome.org/PathwayBrowser/#/R-HSA-2201322 TIRAP is phosphorylated by BTK TAS Homo sapiens 46896 R-HSA-2262775 https://reactome.org/PathwayBrowser/#/R-HSA-2262775 Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 46896 R-HSA-2262777 https://reactome.org/PathwayBrowser/#/R-HSA-2262777 TRAF6 binds to p-IRAK2 TAS Homo sapiens 46896 R-HSA-2559414 https://reactome.org/PathwayBrowser/#/R-HSA-2559414 Activated TLR2/4:TIRAP interacts with BTK TAS Homo sapiens 46896 R-HSA-2559464 https://reactome.org/PathwayBrowser/#/R-HSA-2559464 TLR6/2 ligand associates with CD14 and CD36 within lipid rafts TAS Homo sapiens 46896 R-HSA-5602353 https://reactome.org/PathwayBrowser/#/R-HSA-5602353 Defective IRAK4 variants do not bind MyD88:MAL:BTK:activated TLR2/4 TAS Homo sapiens 46896 R-HSA-5602383 https://reactome.org/PathwayBrowser/#/R-HSA-5602383 Defective MyD88 does not oligomerize within the activated TLR2/4 complex TAS Homo sapiens 46896 R-HSA-5602606 https://reactome.org/PathwayBrowser/#/R-HSA-5602606 Defective MyD88 does not bind MAL(TIRAP):TLR2/4 TAS Homo sapiens 46896 R-HSA-5602672 https://reactome.org/PathwayBrowser/#/R-HSA-5602672 Defective IRAK4 does not bind MyD88 within the TLR2/4 complex TAS Homo sapiens 46896 R-HSA-8863895 https://reactome.org/PathwayBrowser/#/R-HSA-8863895 IKKB phosphorylates SNAP23 TAS Homo sapiens 46896 R-HSA-937022 https://reactome.org/PathwayBrowser/#/R-HSA-937022 IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP TAS Homo sapiens 46896 R-HSA-937059 https://reactome.org/PathwayBrowser/#/R-HSA-937059 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex TAS Homo sapiens 46896 R-HSA-937079 https://reactome.org/PathwayBrowser/#/R-HSA-937079 MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 TAS Homo sapiens 46899 R-HSA-5662891 https://reactome.org/PathwayBrowser/#/R-HSA-5662891 pheomelanin formation TAS Homo sapiens 46899 R-HSA-5662904 https://reactome.org/PathwayBrowser/#/R-HSA-5662904 CD isomers transform to BT, BTCA, BZ, ODHBT TAS Homo sapiens 46911 R-BTA-375770 https://reactome.org/PathwayBrowser/#/R-BTA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Bos taurus 46911 R-BTA-375776 https://reactome.org/PathwayBrowser/#/R-BTA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Bos taurus 46911 R-BTA-452036 https://reactome.org/PathwayBrowser/#/R-BTA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Bos taurus 46911 R-BTA-70560 https://reactome.org/PathwayBrowser/#/R-BTA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Bos taurus 46911 R-BTA-70569 https://reactome.org/PathwayBrowser/#/R-BTA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Bos taurus 46911 R-BTA-70634 https://reactome.org/PathwayBrowser/#/R-BTA-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Bos taurus 46911 R-BTA-70654 https://reactome.org/PathwayBrowser/#/R-BTA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Bos taurus 46911 R-BTA-70666 https://reactome.org/PathwayBrowser/#/R-BTA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Bos taurus 46911 R-BTA-70692 https://reactome.org/PathwayBrowser/#/R-BTA-70692 ornithine => putrescine + CO2 IEA Bos taurus 46911 R-BTA-71275 https://reactome.org/PathwayBrowser/#/R-BTA-71275 arginine + glycine => ornithine + guanidoacetate IEA Bos taurus 46911 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 46911 R-BTA-8959781 https://reactome.org/PathwayBrowser/#/R-BTA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Bos taurus 46911 R-CEL-452036 https://reactome.org/PathwayBrowser/#/R-CEL-452036 arginine + H2O => ornithine + urea [ARG2] IEA Caenorhabditis elegans 46911 R-CEL-70569 https://reactome.org/PathwayBrowser/#/R-CEL-70569 arginine + H2O => ornithine + urea [ARG1] IEA Caenorhabditis elegans 46911 R-CEL-70634 https://reactome.org/PathwayBrowser/#/R-CEL-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Caenorhabditis elegans 46911 R-CEL-70654 https://reactome.org/PathwayBrowser/#/R-CEL-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Caenorhabditis elegans 46911 R-CEL-70666 https://reactome.org/PathwayBrowser/#/R-CEL-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Caenorhabditis elegans 46911 R-CEL-70692 https://reactome.org/PathwayBrowser/#/R-CEL-70692 ornithine => putrescine + CO2 IEA Caenorhabditis elegans 46911 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 46911 R-CEL-8959781 https://reactome.org/PathwayBrowser/#/R-CEL-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Caenorhabditis elegans 46911 R-CFA-375768 https://reactome.org/PathwayBrowser/#/R-CFA-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Canis familiaris 46911 R-CFA-375770 https://reactome.org/PathwayBrowser/#/R-CFA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Canis familiaris 46911 R-CFA-375776 https://reactome.org/PathwayBrowser/#/R-CFA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Canis familiaris 46911 R-CFA-375790 https://reactome.org/PathwayBrowser/#/R-CFA-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Canis familiaris 46911 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 46911 R-CFA-420739 https://reactome.org/PathwayBrowser/#/R-CFA-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Canis familiaris 46911 R-CFA-452036 https://reactome.org/PathwayBrowser/#/R-CFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Canis familiaris 46911 R-CFA-70560 https://reactome.org/PathwayBrowser/#/R-CFA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Canis familiaris 46911 R-CFA-70569 https://reactome.org/PathwayBrowser/#/R-CFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Canis familiaris 46911 R-CFA-70634 https://reactome.org/PathwayBrowser/#/R-CFA-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Canis familiaris 46911 R-CFA-70654 https://reactome.org/PathwayBrowser/#/R-CFA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Canis familiaris 46911 R-CFA-70666 https://reactome.org/PathwayBrowser/#/R-CFA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Canis familiaris 46911 R-CFA-70692 https://reactome.org/PathwayBrowser/#/R-CFA-70692 ornithine => putrescine + CO2 IEA Canis familiaris 46911 R-CFA-71275 https://reactome.org/PathwayBrowser/#/R-CFA-71275 arginine + glycine => ornithine + guanidoacetate IEA Canis familiaris 46911 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 46911 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 46911 R-CFA-8959781 https://reactome.org/PathwayBrowser/#/R-CFA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Canis familiaris 46911 R-DDI-375768 https://reactome.org/PathwayBrowser/#/R-DDI-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 46911 R-DDI-375770 https://reactome.org/PathwayBrowser/#/R-DDI-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 46911 R-DDI-375776 https://reactome.org/PathwayBrowser/#/R-DDI-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 46911 R-DDI-375790 https://reactome.org/PathwayBrowser/#/R-DDI-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Dictyostelium discoideum 46911 R-DDI-452036 https://reactome.org/PathwayBrowser/#/R-DDI-452036 arginine + H2O => ornithine + urea [ARG2] IEA Dictyostelium discoideum 46911 R-DDI-70569 https://reactome.org/PathwayBrowser/#/R-DDI-70569 arginine + H2O => ornithine + urea [ARG1] IEA Dictyostelium discoideum 46911 R-DDI-70634 https://reactome.org/PathwayBrowser/#/R-DDI-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Dictyostelium discoideum 46911 R-DDI-70654 https://reactome.org/PathwayBrowser/#/R-DDI-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Dictyostelium discoideum 46911 R-DDI-70666 https://reactome.org/PathwayBrowser/#/R-DDI-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Dictyostelium discoideum 46911 R-DDI-70692 https://reactome.org/PathwayBrowser/#/R-DDI-70692 ornithine => putrescine + CO2 IEA Dictyostelium discoideum 46911 R-DME-375768 https://reactome.org/PathwayBrowser/#/R-DME-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 46911 R-DME-375770 https://reactome.org/PathwayBrowser/#/R-DME-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 46911 R-DME-375776 https://reactome.org/PathwayBrowser/#/R-DME-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 46911 R-DME-375790 https://reactome.org/PathwayBrowser/#/R-DME-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Drosophila melanogaster 46911 R-DME-452036 https://reactome.org/PathwayBrowser/#/R-DME-452036 arginine + H2O => ornithine + urea [ARG2] IEA Drosophila melanogaster 46911 R-DME-70569 https://reactome.org/PathwayBrowser/#/R-DME-70569 arginine + H2O => ornithine + urea [ARG1] IEA Drosophila melanogaster 46911 R-DME-70634 https://reactome.org/PathwayBrowser/#/R-DME-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Drosophila melanogaster 46911 R-DME-70654 https://reactome.org/PathwayBrowser/#/R-DME-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Drosophila melanogaster 46911 R-DME-70666 https://reactome.org/PathwayBrowser/#/R-DME-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Drosophila melanogaster 46911 R-DME-70692 https://reactome.org/PathwayBrowser/#/R-DME-70692 ornithine => putrescine + CO2 IEA Drosophila melanogaster 46911 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 46911 R-DME-8959781 https://reactome.org/PathwayBrowser/#/R-DME-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Drosophila melanogaster 46911 R-DRE-375768 https://reactome.org/PathwayBrowser/#/R-DRE-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Danio rerio 46911 R-DRE-375776 https://reactome.org/PathwayBrowser/#/R-DRE-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Danio rerio 46911 R-DRE-375790 https://reactome.org/PathwayBrowser/#/R-DRE-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Danio rerio 46911 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 46911 R-DRE-420739 https://reactome.org/PathwayBrowser/#/R-DRE-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Danio rerio 46911 R-DRE-452036 https://reactome.org/PathwayBrowser/#/R-DRE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Danio rerio 46911 R-DRE-70634 https://reactome.org/PathwayBrowser/#/R-DRE-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Danio rerio 46911 R-DRE-70692 https://reactome.org/PathwayBrowser/#/R-DRE-70692 ornithine => putrescine + CO2 IEA Danio rerio 46911 R-DRE-71275 https://reactome.org/PathwayBrowser/#/R-DRE-71275 arginine + glycine => ornithine + guanidoacetate IEA Danio rerio 46911 R-DRE-8959781 https://reactome.org/PathwayBrowser/#/R-DRE-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Danio rerio 46911 R-GGA-187588 https://reactome.org/PathwayBrowser/#/R-GGA-187588 carbamoyl phosphate + ornithine => citrulline + orthophosphate TAS Gallus gallus 46911 R-GGA-187608 https://reactome.org/PathwayBrowser/#/R-GGA-187608 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Gallus gallus 46911 R-GGA-187632 https://reactome.org/PathwayBrowser/#/R-GGA-187632 arginine + H2O => ornithine + urea TAS Gallus gallus 46911 R-GGA-375768 https://reactome.org/PathwayBrowser/#/R-GGA-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Gallus gallus 46911 R-GGA-375770 https://reactome.org/PathwayBrowser/#/R-GGA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Gallus gallus 46911 R-GGA-375776 https://reactome.org/PathwayBrowser/#/R-GGA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Gallus gallus 46911 R-GGA-375790 https://reactome.org/PathwayBrowser/#/R-GGA-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Gallus gallus 46911 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 46911 R-GGA-420739 https://reactome.org/PathwayBrowser/#/R-GGA-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Gallus gallus 46911 R-GGA-452036 https://reactome.org/PathwayBrowser/#/R-GGA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Gallus gallus 46911 R-GGA-70560 https://reactome.org/PathwayBrowser/#/R-GGA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Gallus gallus 46911 R-GGA-70634 https://reactome.org/PathwayBrowser/#/R-GGA-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Gallus gallus 46911 R-GGA-70654 https://reactome.org/PathwayBrowser/#/R-GGA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Gallus gallus 46911 R-GGA-70666 https://reactome.org/PathwayBrowser/#/R-GGA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Gallus gallus 46911 R-GGA-70692 https://reactome.org/PathwayBrowser/#/R-GGA-70692 ornithine => putrescine + CO2 IEA Gallus gallus 46911 R-GGA-71275 https://reactome.org/PathwayBrowser/#/R-GGA-71275 arginine + glycine => ornithine + guanidoacetate IEA Gallus gallus 46911 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 46911 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 46911 R-GGA-8959781 https://reactome.org/PathwayBrowser/#/R-GGA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Gallus gallus 46911 R-HSA-375768 https://reactome.org/PathwayBrowser/#/R-HSA-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids TAS Homo sapiens 46911 R-HSA-375770 https://reactome.org/PathwayBrowser/#/R-HSA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids TAS Homo sapiens 46911 R-HSA-375776 https://reactome.org/PathwayBrowser/#/R-HSA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids TAS Homo sapiens 46911 R-HSA-375790 https://reactome.org/PathwayBrowser/#/R-HSA-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids TAS Homo sapiens 46911 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 46911 R-HSA-420739 https://reactome.org/PathwayBrowser/#/R-HSA-420739 GPRC6A can bind L-alpha amino acids and calcium TAS Homo sapiens 46911 R-HSA-452036 https://reactome.org/PathwayBrowser/#/R-HSA-452036 arginine + H2O => ornithine + urea [ARG2] TAS Homo sapiens 46911 R-HSA-70560 https://reactome.org/PathwayBrowser/#/R-HSA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate TAS Homo sapiens 46911 R-HSA-70569 https://reactome.org/PathwayBrowser/#/R-HSA-70569 arginine + H2O => ornithine + urea [ARG1] TAS Homo sapiens 46911 R-HSA-70634 https://reactome.org/PathwayBrowser/#/R-HSA-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) TAS Homo sapiens 46911 R-HSA-70654 https://reactome.org/PathwayBrowser/#/R-HSA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] TAS Homo sapiens 46911 R-HSA-70666 https://reactome.org/PathwayBrowser/#/R-HSA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] TAS Homo sapiens 46911 R-HSA-70692 https://reactome.org/PathwayBrowser/#/R-HSA-70692 ornithine => putrescine + CO2 TAS Homo sapiens 46911 R-HSA-71275 https://reactome.org/PathwayBrowser/#/R-HSA-71275 arginine + glycine => ornithine + guanidoacetate TAS Homo sapiens 46911 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 46911 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 46911 R-HSA-8959781 https://reactome.org/PathwayBrowser/#/R-HSA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix TAS Homo sapiens 46911 R-MMU-375770 https://reactome.org/PathwayBrowser/#/R-MMU-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Mus musculus 46911 R-MMU-375776 https://reactome.org/PathwayBrowser/#/R-MMU-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Mus musculus 46911 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 46911 R-MMU-420739 https://reactome.org/PathwayBrowser/#/R-MMU-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Mus musculus 46911 R-MMU-452036 https://reactome.org/PathwayBrowser/#/R-MMU-452036 arginine + H2O => ornithine + urea [ARG2] IEA Mus musculus 46911 R-MMU-70560 https://reactome.org/PathwayBrowser/#/R-MMU-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Mus musculus 46911 R-MMU-70569 https://reactome.org/PathwayBrowser/#/R-MMU-70569 arginine + H2O => ornithine + urea [ARG1] IEA Mus musculus 46911 R-MMU-70634 https://reactome.org/PathwayBrowser/#/R-MMU-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Mus musculus 46911 R-MMU-70654 https://reactome.org/PathwayBrowser/#/R-MMU-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Mus musculus 46911 R-MMU-70666 https://reactome.org/PathwayBrowser/#/R-MMU-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Mus musculus 46911 R-MMU-70692 https://reactome.org/PathwayBrowser/#/R-MMU-70692 ornithine => putrescine + CO2 IEA Mus musculus 46911 R-MMU-71275 https://reactome.org/PathwayBrowser/#/R-MMU-71275 arginine + glycine => ornithine + guanidoacetate IEA Mus musculus 46911 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 46911 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 46911 R-MMU-8959781 https://reactome.org/PathwayBrowser/#/R-MMU-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Mus musculus 46911 R-PFA-452036 https://reactome.org/PathwayBrowser/#/R-PFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Plasmodium falciparum 46911 R-PFA-70569 https://reactome.org/PathwayBrowser/#/R-PFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Plasmodium falciparum 46911 R-PFA-70654 https://reactome.org/PathwayBrowser/#/R-PFA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Plasmodium falciparum 46911 R-PFA-70666 https://reactome.org/PathwayBrowser/#/R-PFA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Plasmodium falciparum 46911 R-PFA-70692 https://reactome.org/PathwayBrowser/#/R-PFA-70692 ornithine => putrescine + CO2 IEA Plasmodium falciparum 46911 R-RNO-375770 https://reactome.org/PathwayBrowser/#/R-RNO-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Rattus norvegicus 46911 R-RNO-375776 https://reactome.org/PathwayBrowser/#/R-RNO-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Rattus norvegicus 46911 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 46911 R-RNO-420739 https://reactome.org/PathwayBrowser/#/R-RNO-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Rattus norvegicus 46911 R-RNO-452036 https://reactome.org/PathwayBrowser/#/R-RNO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Rattus norvegicus 46911 R-RNO-70560 https://reactome.org/PathwayBrowser/#/R-RNO-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Rattus norvegicus 46911 R-RNO-70569 https://reactome.org/PathwayBrowser/#/R-RNO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Rattus norvegicus 46911 R-RNO-70634 https://reactome.org/PathwayBrowser/#/R-RNO-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Rattus norvegicus 46911 R-RNO-70654 https://reactome.org/PathwayBrowser/#/R-RNO-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Rattus norvegicus 46911 R-RNO-70666 https://reactome.org/PathwayBrowser/#/R-RNO-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Rattus norvegicus 46911 R-RNO-70692 https://reactome.org/PathwayBrowser/#/R-RNO-70692 ornithine => putrescine + CO2 IEA Rattus norvegicus 46911 R-RNO-71275 https://reactome.org/PathwayBrowser/#/R-RNO-71275 arginine + glycine => ornithine + guanidoacetate IEA Rattus norvegicus 46911 R-RNO-8959781 https://reactome.org/PathwayBrowser/#/R-RNO-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Rattus norvegicus 46911 R-SCE-452036 https://reactome.org/PathwayBrowser/#/R-SCE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Saccharomyces cerevisiae 46911 R-SCE-70560 https://reactome.org/PathwayBrowser/#/R-SCE-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Saccharomyces cerevisiae 46911 R-SCE-70569 https://reactome.org/PathwayBrowser/#/R-SCE-70569 arginine + H2O => ornithine + urea [ARG1] IEA Saccharomyces cerevisiae 46911 R-SCE-70634 https://reactome.org/PathwayBrowser/#/R-SCE-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Saccharomyces cerevisiae 46911 R-SCE-70654 https://reactome.org/PathwayBrowser/#/R-SCE-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Saccharomyces cerevisiae 46911 R-SCE-70666 https://reactome.org/PathwayBrowser/#/R-SCE-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Saccharomyces cerevisiae 46911 R-SCE-70692 https://reactome.org/PathwayBrowser/#/R-SCE-70692 ornithine => putrescine + CO2 IEA Saccharomyces cerevisiae 46911 R-SPO-452036 https://reactome.org/PathwayBrowser/#/R-SPO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Schizosaccharomyces pombe 46911 R-SPO-70560 https://reactome.org/PathwayBrowser/#/R-SPO-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Schizosaccharomyces pombe 46911 R-SPO-70569 https://reactome.org/PathwayBrowser/#/R-SPO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Schizosaccharomyces pombe 46911 R-SPO-70634 https://reactome.org/PathwayBrowser/#/R-SPO-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Schizosaccharomyces pombe 46911 R-SPO-70654 https://reactome.org/PathwayBrowser/#/R-SPO-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Schizosaccharomyces pombe 46911 R-SPO-70666 https://reactome.org/PathwayBrowser/#/R-SPO-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Schizosaccharomyces pombe 46911 R-SPO-70692 https://reactome.org/PathwayBrowser/#/R-SPO-70692 ornithine => putrescine + CO2 IEA Schizosaccharomyces pombe 46911 R-SSC-375768 https://reactome.org/PathwayBrowser/#/R-SSC-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Sus scrofa 46911 R-SSC-375770 https://reactome.org/PathwayBrowser/#/R-SSC-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Sus scrofa 46911 R-SSC-375776 https://reactome.org/PathwayBrowser/#/R-SSC-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Sus scrofa 46911 R-SSC-375790 https://reactome.org/PathwayBrowser/#/R-SSC-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Sus scrofa 46911 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 46911 R-SSC-420739 https://reactome.org/PathwayBrowser/#/R-SSC-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Sus scrofa 46911 R-SSC-452036 https://reactome.org/PathwayBrowser/#/R-SSC-452036 arginine + H2O => ornithine + urea [ARG2] IEA Sus scrofa 46911 R-SSC-70560 https://reactome.org/PathwayBrowser/#/R-SSC-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Sus scrofa 46911 R-SSC-70569 https://reactome.org/PathwayBrowser/#/R-SSC-70569 arginine + H2O => ornithine + urea [ARG1] IEA Sus scrofa 46911 R-SSC-70634 https://reactome.org/PathwayBrowser/#/R-SSC-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Sus scrofa 46911 R-SSC-70654 https://reactome.org/PathwayBrowser/#/R-SSC-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Sus scrofa 46911 R-SSC-70666 https://reactome.org/PathwayBrowser/#/R-SSC-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Sus scrofa 46911 R-SSC-70692 https://reactome.org/PathwayBrowser/#/R-SSC-70692 ornithine => putrescine + CO2 IEA Sus scrofa 46911 R-SSC-71275 https://reactome.org/PathwayBrowser/#/R-SSC-71275 arginine + glycine => ornithine + guanidoacetate IEA Sus scrofa 46911 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 46911 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 46911 R-XTR-375768 https://reactome.org/PathwayBrowser/#/R-XTR-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 46911 R-XTR-375770 https://reactome.org/PathwayBrowser/#/R-XTR-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 46911 R-XTR-375776 https://reactome.org/PathwayBrowser/#/R-XTR-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 46911 R-XTR-375790 https://reactome.org/PathwayBrowser/#/R-XTR-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids IEA Xenopus tropicalis 46911 R-XTR-420739 https://reactome.org/PathwayBrowser/#/R-XTR-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Xenopus tropicalis 46911 R-XTR-452036 https://reactome.org/PathwayBrowser/#/R-XTR-452036 arginine + H2O => ornithine + urea [ARG2] IEA Xenopus tropicalis 46911 R-XTR-70560 https://reactome.org/PathwayBrowser/#/R-XTR-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Xenopus tropicalis 46911 R-XTR-70569 https://reactome.org/PathwayBrowser/#/R-XTR-70569 arginine + H2O => ornithine + urea [ARG1] IEA Xenopus tropicalis 46911 R-XTR-70634 https://reactome.org/PathwayBrowser/#/R-XTR-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Xenopus tropicalis 46911 R-XTR-70654 https://reactome.org/PathwayBrowser/#/R-XTR-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Xenopus tropicalis 46911 R-XTR-70666 https://reactome.org/PathwayBrowser/#/R-XTR-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Xenopus tropicalis 46911 R-XTR-70692 https://reactome.org/PathwayBrowser/#/R-XTR-70692 ornithine => putrescine + CO2 IEA Xenopus tropicalis 46911 R-XTR-71275 https://reactome.org/PathwayBrowser/#/R-XTR-71275 arginine + glycine => ornithine + guanidoacetate IEA Xenopus tropicalis 46911 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 46911 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 46911 R-XTR-8959781 https://reactome.org/PathwayBrowser/#/R-XTR-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix IEA Xenopus tropicalis 47013 R-BTA-8955844 https://reactome.org/PathwayBrowser/#/R-BTA-8955844 RBKS phosphorylates ribose to R5P IEA Bos taurus 47013 R-CEL-8955844 https://reactome.org/PathwayBrowser/#/R-CEL-8955844 RBKS phosphorylates ribose to R5P IEA Caenorhabditis elegans 47013 R-CFA-8955844 https://reactome.org/PathwayBrowser/#/R-CFA-8955844 RBKS phosphorylates ribose to R5P IEA Canis familiaris 47013 R-DDI-8955844 https://reactome.org/PathwayBrowser/#/R-DDI-8955844 RBKS phosphorylates ribose to R5P IEA Dictyostelium discoideum 47013 R-DME-8955844 https://reactome.org/PathwayBrowser/#/R-DME-8955844 RBKS phosphorylates ribose to R5P IEA Drosophila melanogaster 47013 R-DRE-8955844 https://reactome.org/PathwayBrowser/#/R-DRE-8955844 RBKS phosphorylates ribose to R5P IEA Danio rerio 47013 R-GGA-8955844 https://reactome.org/PathwayBrowser/#/R-GGA-8955844 RBKS phosphorylates ribose to R5P IEA Gallus gallus 47013 R-HSA-8955844 https://reactome.org/PathwayBrowser/#/R-HSA-8955844 RBKS phosphorylates ribose to R5P TAS Homo sapiens 47013 R-MMU-8955844 https://reactome.org/PathwayBrowser/#/R-MMU-8955844 RBKS phosphorylates ribose to R5P IEA Mus musculus 47013 R-RNO-8955844 https://reactome.org/PathwayBrowser/#/R-RNO-8955844 RBKS phosphorylates ribose to R5P IEA Rattus norvegicus 47013 R-SCE-8955844 https://reactome.org/PathwayBrowser/#/R-SCE-8955844 RBKS phosphorylates ribose to R5P IEA Saccharomyces cerevisiae 47013 R-SPO-8955844 https://reactome.org/PathwayBrowser/#/R-SPO-8955844 RBKS phosphorylates ribose to R5P IEA Schizosaccharomyces pombe 47013 R-SSC-8955844 https://reactome.org/PathwayBrowser/#/R-SSC-8955844 RBKS phosphorylates ribose to R5P IEA Sus scrofa 47013 R-XTR-8955844 https://reactome.org/PathwayBrowser/#/R-XTR-8955844 RBKS phosphorylates ribose to R5P IEA Xenopus tropicalis 47037 R-BTA-9013869 https://reactome.org/PathwayBrowser/#/R-BTA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Bos taurus 47037 R-CEL-9013869 https://reactome.org/PathwayBrowser/#/R-CEL-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Caenorhabditis elegans 47037 R-CFA-9013869 https://reactome.org/PathwayBrowser/#/R-CFA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Canis familiaris 47037 R-DDI-9013869 https://reactome.org/PathwayBrowser/#/R-DDI-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Dictyostelium discoideum 47037 R-DME-9013869 https://reactome.org/PathwayBrowser/#/R-DME-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Drosophila melanogaster 47037 R-GGA-9013869 https://reactome.org/PathwayBrowser/#/R-GGA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Gallus gallus 47037 R-HSA-1834939 https://reactome.org/PathwayBrowser/#/R-HSA-1834939 STING recruits TBK1 and IRF3 TAS Homo sapiens 47037 R-HSA-9013869 https://reactome.org/PathwayBrowser/#/R-HSA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP TAS Homo sapiens 47037 R-MMU-9013869 https://reactome.org/PathwayBrowser/#/R-MMU-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Mus musculus 47037 R-RNO-9013869 https://reactome.org/PathwayBrowser/#/R-RNO-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Rattus norvegicus 47037 R-SSC-9013869 https://reactome.org/PathwayBrowser/#/R-SSC-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Sus scrofa 47037 R-XTR-9013869 https://reactome.org/PathwayBrowser/#/R-XTR-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Xenopus tropicalis 4705 R-BTA-1234167 https://reactome.org/PathwayBrowser/#/R-BTA-1234167 Formation of HIF:CBP:p300 complex at promoters IEA Bos taurus 4705 R-BTA-212222 https://reactome.org/PathwayBrowser/#/R-BTA-212222 PRC2 recruits DNA methyltransferases IEA Bos taurus 4705 R-BTA-212252 https://reactome.org/PathwayBrowser/#/R-BTA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Bos taurus 4705 R-BTA-212263 https://reactome.org/PathwayBrowser/#/R-BTA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Bos taurus 4705 R-BTA-212269 https://reactome.org/PathwayBrowser/#/R-BTA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Bos taurus 4705 R-BTA-2203480 https://reactome.org/PathwayBrowser/#/R-BTA-2203480 COLEC11 binds ligands IEA Bos taurus 4705 R-BTA-266204 https://reactome.org/PathwayBrowser/#/R-BTA-266204 Association of HMGB1/HMGB2 with chromatin IEA Bos taurus 4705 R-BTA-427337 https://reactome.org/PathwayBrowser/#/R-BTA-427337 MBD2 binds methylcytosine in chromatin IEA Bos taurus 4705 R-BTA-427514 https://reactome.org/PathwayBrowser/#/R-BTA-427514 eNoSC deacetylates histone H3 IEA Bos taurus 4705 R-BTA-427527 https://reactome.org/PathwayBrowser/#/R-BTA-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Bos taurus 4705 R-BTA-427528 https://reactome.org/PathwayBrowser/#/R-BTA-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Bos taurus 4705 R-BTA-4755536 https://reactome.org/PathwayBrowser/#/R-BTA-4755536 PIAS3 SUMOylates RELA with SUMO3 IEA Bos taurus 4705 R-BTA-5220959 https://reactome.org/PathwayBrowser/#/R-BTA-5220959 TDG excises 5-formylcytosine IEA Bos taurus 4705 R-BTA-5221061 https://reactome.org/PathwayBrowser/#/R-BTA-5221061 TDG excises 5-carboxylcytosine IEA Bos taurus 4705 R-BTA-5358510 https://reactome.org/PathwayBrowser/#/R-BTA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Bos taurus 4705 R-BTA-5358513 https://reactome.org/PathwayBrowser/#/R-BTA-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Bos taurus 4705 R-BTA-5358518 https://reactome.org/PathwayBrowser/#/R-BTA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Bos taurus 4705 R-BTA-5358525 https://reactome.org/PathwayBrowser/#/R-BTA-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Bos taurus 4705 R-BTA-5358579 https://reactome.org/PathwayBrowser/#/R-BTA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Bos taurus 4705 R-BTA-5358592 https://reactome.org/PathwayBrowser/#/R-BTA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Bos taurus 4705 R-BTA-5358597 https://reactome.org/PathwayBrowser/#/R-BTA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Bos taurus 4705 R-BTA-5358599 https://reactome.org/PathwayBrowser/#/R-BTA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Bos taurus 4705 R-BTA-5358912 https://reactome.org/PathwayBrowser/#/R-BTA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Bos taurus 4705 R-BTA-5578742 https://reactome.org/PathwayBrowser/#/R-BTA-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Bos taurus 4705 R-BTA-606287 https://reactome.org/PathwayBrowser/#/R-BTA-606287 RSF complex binds the centromere IEA Bos taurus 4705 R-BTA-606289 https://reactome.org/PathwayBrowser/#/R-BTA-606289 New CENPA-containing nucleosomes are deposited at the centromere IEA Bos taurus 4705 R-BTA-606326 https://reactome.org/PathwayBrowser/#/R-BTA-606326 HJURP:CENPA complex localizes to the centromere IEA Bos taurus 4705 R-BTA-606349 https://reactome.org/PathwayBrowser/#/R-BTA-606349 Mis18 complex binds the centromere IEA Bos taurus 4705 R-BTA-73718 https://reactome.org/PathwayBrowser/#/R-BTA-73718 UBF-1 Binds rDNA Promoter IEA Bos taurus 4705 R-BTA-74986 https://reactome.org/PathwayBrowser/#/R-BTA-74986 Elongation of pre-rRNA transcript IEA Bos taurus 4705 R-BTA-77077 https://reactome.org/PathwayBrowser/#/R-BTA-77077 Capping complex formation IEA Bos taurus 4705 R-BTA-77078 https://reactome.org/PathwayBrowser/#/R-BTA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Bos taurus 4705 R-BTA-77081 https://reactome.org/PathwayBrowser/#/R-BTA-77081 Formation of the CE:GMP intermediate complex IEA Bos taurus 4705 R-BTA-77083 https://reactome.org/PathwayBrowser/#/R-BTA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Bos taurus 4705 R-BTA-77085 https://reactome.org/PathwayBrowser/#/R-BTA-77085 Dissociation of transcript with 5'-GMP from GT IEA Bos taurus 4705 R-BTA-77090 https://reactome.org/PathwayBrowser/#/R-BTA-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Bos taurus 4705 R-CEL-1234167 https://reactome.org/PathwayBrowser/#/R-CEL-1234167 Formation of HIF:CBP:p300 complex at promoters IEA Caenorhabditis elegans 4705 R-CEL-266204 https://reactome.org/PathwayBrowser/#/R-CEL-266204 Association of HMGB1/HMGB2 with chromatin IEA Caenorhabditis elegans 4705 R-CEL-4647594 https://reactome.org/PathwayBrowser/#/R-CEL-4647594 SAHF formation IEA Caenorhabditis elegans 4705 R-CEL-5358510 https://reactome.org/PathwayBrowser/#/R-CEL-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Caenorhabditis elegans 4705 R-CEL-5358518 https://reactome.org/PathwayBrowser/#/R-CEL-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Caenorhabditis elegans 4705 R-CEL-5358525 https://reactome.org/PathwayBrowser/#/R-CEL-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Caenorhabditis elegans 4705 R-CEL-5358592 https://reactome.org/PathwayBrowser/#/R-CEL-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Caenorhabditis elegans 4705 R-CEL-5358597 https://reactome.org/PathwayBrowser/#/R-CEL-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Caenorhabditis elegans 4705 R-CEL-5358912 https://reactome.org/PathwayBrowser/#/R-CEL-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Caenorhabditis elegans 4705 R-CEL-5578742 https://reactome.org/PathwayBrowser/#/R-CEL-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Caenorhabditis elegans 4705 R-CEL-74986 https://reactome.org/PathwayBrowser/#/R-CEL-74986 Elongation of pre-rRNA transcript IEA Caenorhabditis elegans 4705 R-CEL-77077 https://reactome.org/PathwayBrowser/#/R-CEL-77077 Capping complex formation IEA Caenorhabditis elegans 4705 R-CEL-77078 https://reactome.org/PathwayBrowser/#/R-CEL-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Caenorhabditis elegans 4705 R-CEL-77081 https://reactome.org/PathwayBrowser/#/R-CEL-77081 Formation of the CE:GMP intermediate complex IEA Caenorhabditis elegans 4705 R-CEL-77083 https://reactome.org/PathwayBrowser/#/R-CEL-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Caenorhabditis elegans 4705 R-CEL-77085 https://reactome.org/PathwayBrowser/#/R-CEL-77085 Dissociation of transcript with 5'-GMP from GT IEA Caenorhabditis elegans 4705 R-CEL-77090 https://reactome.org/PathwayBrowser/#/R-CEL-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Caenorhabditis elegans 4705 R-CFA-1234167 https://reactome.org/PathwayBrowser/#/R-CFA-1234167 Formation of HIF:CBP:p300 complex at promoters IEA Canis familiaris 4705 R-CFA-211239 https://reactome.org/PathwayBrowser/#/R-CFA-211239 Association of DFF40 with chromatin IEA Canis familiaris 4705 R-CFA-211247 https://reactome.org/PathwayBrowser/#/R-CFA-211247 Cleavage of DNA by DFF40 IEA Canis familiaris 4705 R-CFA-212222 https://reactome.org/PathwayBrowser/#/R-CFA-212222 PRC2 recruits DNA methyltransferases IEA Canis familiaris 4705 R-CFA-212252 https://reactome.org/PathwayBrowser/#/R-CFA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Canis familiaris 4705 R-CFA-212263 https://reactome.org/PathwayBrowser/#/R-CFA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Canis familiaris 4705 R-CFA-212269 https://reactome.org/PathwayBrowser/#/R-CFA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Canis familiaris 4705 R-CFA-266204 https://reactome.org/PathwayBrowser/#/R-CFA-266204 Association of HMGB1/HMGB2 with chromatin IEA Canis familiaris 4705 R-CFA-427337 https://reactome.org/PathwayBrowser/#/R-CFA-427337 MBD2 binds methylcytosine in chromatin IEA Canis familiaris 4705 R-CFA-427514 https://reactome.org/PathwayBrowser/#/R-CFA-427514 eNoSC deacetylates histone H3 IEA Canis familiaris 4705 R-CFA-427527 https://reactome.org/PathwayBrowser/#/R-CFA-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Canis familiaris 4705 R-CFA-427528 https://reactome.org/PathwayBrowser/#/R-CFA-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Canis familiaris 4705 R-CFA-4647594 https://reactome.org/PathwayBrowser/#/R-CFA-4647594 SAHF formation IEA Canis familiaris 4705 R-CFA-5220959 https://reactome.org/PathwayBrowser/#/R-CFA-5220959 TDG excises 5-formylcytosine IEA Canis familiaris 4705 R-CFA-5221061 https://reactome.org/PathwayBrowser/#/R-CFA-5221061 TDG excises 5-carboxylcytosine IEA Canis familiaris 4705 R-CFA-5358510 https://reactome.org/PathwayBrowser/#/R-CFA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Canis familiaris 4705 R-CFA-5358513 https://reactome.org/PathwayBrowser/#/R-CFA-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Canis familiaris 4705 R-CFA-5358518 https://reactome.org/PathwayBrowser/#/R-CFA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Canis familiaris 4705 R-CFA-5358525 https://reactome.org/PathwayBrowser/#/R-CFA-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Canis familiaris 4705 R-CFA-5358579 https://reactome.org/PathwayBrowser/#/R-CFA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Canis familiaris 4705 R-CFA-5358592 https://reactome.org/PathwayBrowser/#/R-CFA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Canis familiaris 4705 R-CFA-5358597 https://reactome.org/PathwayBrowser/#/R-CFA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Canis familiaris 4705 R-CFA-5358599 https://reactome.org/PathwayBrowser/#/R-CFA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Canis familiaris 4705 R-CFA-5358912 https://reactome.org/PathwayBrowser/#/R-CFA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Canis familiaris 4705 R-CFA-5578742 https://reactome.org/PathwayBrowser/#/R-CFA-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Canis familiaris 4705 R-CFA-606326 https://reactome.org/PathwayBrowser/#/R-CFA-606326 HJURP:CENPA complex localizes to the centromere IEA Canis familiaris 4705 R-CFA-606349 https://reactome.org/PathwayBrowser/#/R-CFA-606349 Mis18 complex binds the centromere IEA Canis familiaris 4705 R-CFA-73718 https://reactome.org/PathwayBrowser/#/R-CFA-73718 UBF-1 Binds rDNA Promoter IEA Canis familiaris 4705 R-CFA-74986 https://reactome.org/PathwayBrowser/#/R-CFA-74986 Elongation of pre-rRNA transcript IEA Canis familiaris 4705 R-CFA-77077 https://reactome.org/PathwayBrowser/#/R-CFA-77077 Capping complex formation IEA Canis familiaris 4705 R-CFA-77078 https://reactome.org/PathwayBrowser/#/R-CFA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Canis familiaris 4705 R-CFA-77081 https://reactome.org/PathwayBrowser/#/R-CFA-77081 Formation of the CE:GMP intermediate complex IEA Canis familiaris 4705 R-CFA-77083 https://reactome.org/PathwayBrowser/#/R-CFA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Canis familiaris 4705 R-CFA-77085 https://reactome.org/PathwayBrowser/#/R-CFA-77085 Dissociation of transcript with 5'-GMP from GT IEA Canis familiaris 4705 R-CFA-77090 https://reactome.org/PathwayBrowser/#/R-CFA-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Canis familiaris 4705 R-DDI-266204 https://reactome.org/PathwayBrowser/#/R-DDI-266204 Association of HMGB1/HMGB2 with chromatin IEA Dictyostelium discoideum 4705 R-DDI-427514 https://reactome.org/PathwayBrowser/#/R-DDI-427514 eNoSC deacetylates histone H3 IEA Dictyostelium discoideum 4705 R-DDI-427527 https://reactome.org/PathwayBrowser/#/R-DDI-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Dictyostelium discoideum 4705 R-DDI-5358510 https://reactome.org/PathwayBrowser/#/R-DDI-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Dictyostelium discoideum 4705 R-DDI-5358513 https://reactome.org/PathwayBrowser/#/R-DDI-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Dictyostelium discoideum 4705 R-DDI-5358518 https://reactome.org/PathwayBrowser/#/R-DDI-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Dictyostelium discoideum 4705 R-DDI-5358525 https://reactome.org/PathwayBrowser/#/R-DDI-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Dictyostelium discoideum 4705 R-DDI-5358592 https://reactome.org/PathwayBrowser/#/R-DDI-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Dictyostelium discoideum 4705 R-DDI-5358597 https://reactome.org/PathwayBrowser/#/R-DDI-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Dictyostelium discoideum 4705 R-DDI-5358912 https://reactome.org/PathwayBrowser/#/R-DDI-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Dictyostelium discoideum 4705 R-DDI-74986 https://reactome.org/PathwayBrowser/#/R-DDI-74986 Elongation of pre-rRNA transcript IEA Dictyostelium discoideum 4705 R-DDI-77077 https://reactome.org/PathwayBrowser/#/R-DDI-77077 Capping complex formation IEA Dictyostelium discoideum 4705 R-DDI-77078 https://reactome.org/PathwayBrowser/#/R-DDI-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Dictyostelium discoideum 4705 R-DDI-77081 https://reactome.org/PathwayBrowser/#/R-DDI-77081 Formation of the CE:GMP intermediate complex IEA Dictyostelium discoideum 4705 R-DDI-77083 https://reactome.org/PathwayBrowser/#/R-DDI-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Dictyostelium discoideum 4705 R-DDI-77085 https://reactome.org/PathwayBrowser/#/R-DDI-77085 Dissociation of transcript with 5'-GMP from GT IEA Dictyostelium discoideum 4705 R-DDI-77090 https://reactome.org/PathwayBrowser/#/R-DDI-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Dictyostelium discoideum 4705 R-DME-1234167 https://reactome.org/PathwayBrowser/#/R-DME-1234167 Formation of HIF:CBP:p300 complex at promoters IEA Drosophila melanogaster 4705 R-DME-212252 https://reactome.org/PathwayBrowser/#/R-DME-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Drosophila melanogaster 4705 R-DME-212263 https://reactome.org/PathwayBrowser/#/R-DME-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Drosophila melanogaster 4705 R-DME-212269 https://reactome.org/PathwayBrowser/#/R-DME-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Drosophila melanogaster 4705 R-DME-266204 https://reactome.org/PathwayBrowser/#/R-DME-266204 Association of HMGB1/HMGB2 with chromatin IEA Drosophila melanogaster 4705 R-DME-427337 https://reactome.org/PathwayBrowser/#/R-DME-427337 MBD2 binds methylcytosine in chromatin IEA Drosophila melanogaster 4705 R-DME-427514 https://reactome.org/PathwayBrowser/#/R-DME-427514 eNoSC deacetylates histone H3 IEA Drosophila melanogaster 4705 R-DME-427527 https://reactome.org/PathwayBrowser/#/R-DME-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Drosophila melanogaster 4705 R-DME-427528 https://reactome.org/PathwayBrowser/#/R-DME-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Drosophila melanogaster 4705 R-DME-432381 https://reactome.org/PathwayBrowser/#/R-DME-432381 PDP1 replaces VRI as binder to Clk and cry genes TAS Drosophila melanogaster 4705 R-DME-432436 https://reactome.org/PathwayBrowser/#/R-DME-432436 CLK:CYC heterodimer binds to per, tim, vri, and Pdp1 genes TAS Drosophila melanogaster 4705 R-DME-432487 https://reactome.org/PathwayBrowser/#/R-DME-432487 CWO binds to cwo gene and represses transcription TAS Drosophila melanogaster 4705 R-DME-432513 https://reactome.org/PathwayBrowser/#/R-DME-432513 CLK is phosphorylated by DCO TAS Drosophila melanogaster 4705 R-DME-432520 https://reactome.org/PathwayBrowser/#/R-DME-432520 CLK:CYC heterodimer binds to cwo gene and activates transcription TAS Drosophila melanogaster 4705 R-DME-432607 https://reactome.org/PathwayBrowser/#/R-DME-432607 VRI replaces PDP1 as binder to Clk and cry genes TAS Drosophila melanogaster 4705 R-DME-4755536 https://reactome.org/PathwayBrowser/#/R-DME-4755536 PIAS3 SUMOylates RELA with SUMO3 IEA Drosophila melanogaster 4705 R-DME-5220959 https://reactome.org/PathwayBrowser/#/R-DME-5220959 TDG excises 5-formylcytosine IEA Drosophila melanogaster 4705 R-DME-5221061 https://reactome.org/PathwayBrowser/#/R-DME-5221061 TDG excises 5-carboxylcytosine IEA Drosophila melanogaster 4705 R-DME-5358510 https://reactome.org/PathwayBrowser/#/R-DME-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Drosophila melanogaster 4705 R-DME-5358518 https://reactome.org/PathwayBrowser/#/R-DME-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Drosophila melanogaster 4705 R-DME-5358525 https://reactome.org/PathwayBrowser/#/R-DME-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Drosophila melanogaster 4705 R-DME-5358592 https://reactome.org/PathwayBrowser/#/R-DME-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Drosophila melanogaster 4705 R-DME-5358597 https://reactome.org/PathwayBrowser/#/R-DME-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Drosophila melanogaster 4705 R-DME-5358599 https://reactome.org/PathwayBrowser/#/R-DME-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Drosophila melanogaster 4705 R-DME-5358912 https://reactome.org/PathwayBrowser/#/R-DME-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Drosophila melanogaster 4705 R-DME-538891 https://reactome.org/PathwayBrowser/#/R-DME-538891 CLK:CYC heterodimer dissociates from per, tim, vri, and Pdp1 genes TAS Drosophila melanogaster 4705 R-DME-538904 https://reactome.org/PathwayBrowser/#/R-DME-538904 Phosphorylated PER binds to CLK TAS Drosophila melanogaster 4705 R-DME-5578742 https://reactome.org/PathwayBrowser/#/R-DME-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Drosophila melanogaster 4705 R-DME-74986 https://reactome.org/PathwayBrowser/#/R-DME-74986 Elongation of pre-rRNA transcript IEA Drosophila melanogaster 4705 R-DME-77077 https://reactome.org/PathwayBrowser/#/R-DME-77077 Capping complex formation IEA Drosophila melanogaster 4705 R-DME-77078 https://reactome.org/PathwayBrowser/#/R-DME-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Drosophila melanogaster 4705 R-DME-77081 https://reactome.org/PathwayBrowser/#/R-DME-77081 Formation of the CE:GMP intermediate complex IEA Drosophila melanogaster 4705 R-DME-77083 https://reactome.org/PathwayBrowser/#/R-DME-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Drosophila melanogaster 4705 R-DME-77085 https://reactome.org/PathwayBrowser/#/R-DME-77085 Dissociation of transcript with 5'-GMP from GT IEA Drosophila melanogaster 4705 R-DME-77090 https://reactome.org/PathwayBrowser/#/R-DME-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Drosophila melanogaster 4705 R-DRE-211239 https://reactome.org/PathwayBrowser/#/R-DRE-211239 Association of DFF40 with chromatin IEA Danio rerio 4705 R-DRE-211247 https://reactome.org/PathwayBrowser/#/R-DRE-211247 Cleavage of DNA by DFF40 IEA Danio rerio 4705 R-DRE-212222 https://reactome.org/PathwayBrowser/#/R-DRE-212222 PRC2 recruits DNA methyltransferases IEA Danio rerio 4705 R-DRE-212252 https://reactome.org/PathwayBrowser/#/R-DRE-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Danio rerio 4705 R-DRE-212263 https://reactome.org/PathwayBrowser/#/R-DRE-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Danio rerio 4705 R-DRE-212269 https://reactome.org/PathwayBrowser/#/R-DRE-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Danio rerio 4705 R-DRE-266204 https://reactome.org/PathwayBrowser/#/R-DRE-266204 Association of HMGB1/HMGB2 with chromatin IEA Danio rerio 4705 R-DRE-427337 https://reactome.org/PathwayBrowser/#/R-DRE-427337 MBD2 binds methylcytosine in chromatin IEA Danio rerio 4705 R-DRE-5220959 https://reactome.org/PathwayBrowser/#/R-DRE-5220959 TDG excises 5-formylcytosine IEA Danio rerio 4705 R-DRE-5221061 https://reactome.org/PathwayBrowser/#/R-DRE-5221061 TDG excises 5-carboxylcytosine IEA Danio rerio 4705 R-DRE-5358518 https://reactome.org/PathwayBrowser/#/R-DRE-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Danio rerio 4705 R-DRE-5358525 https://reactome.org/PathwayBrowser/#/R-DRE-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Danio rerio 4705 R-DRE-5358597 https://reactome.org/PathwayBrowser/#/R-DRE-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Danio rerio 4705 R-DRE-5358599 https://reactome.org/PathwayBrowser/#/R-DRE-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Danio rerio 4705 R-DRE-5358912 https://reactome.org/PathwayBrowser/#/R-DRE-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Danio rerio 4705 R-DRE-73718 https://reactome.org/PathwayBrowser/#/R-DRE-73718 UBF-1 Binds rDNA Promoter IEA Danio rerio 4705 R-DRE-77077 https://reactome.org/PathwayBrowser/#/R-DRE-77077 Capping complex formation IEA Danio rerio 4705 R-DRE-77078 https://reactome.org/PathwayBrowser/#/R-DRE-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Danio rerio 4705 R-DRE-77081 https://reactome.org/PathwayBrowser/#/R-DRE-77081 Formation of the CE:GMP intermediate complex IEA Danio rerio 4705 R-DRE-77083 https://reactome.org/PathwayBrowser/#/R-DRE-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Danio rerio 4705 R-DRE-77085 https://reactome.org/PathwayBrowser/#/R-DRE-77085 Dissociation of transcript with 5'-GMP from GT IEA Danio rerio 4705 R-GGA-1234167 https://reactome.org/PathwayBrowser/#/R-GGA-1234167 Formation of HIF:CBP:p300 complex at promoters IEA Gallus gallus 4705 R-GGA-212222 https://reactome.org/PathwayBrowser/#/R-GGA-212222 PRC2 recruits DNA methyltransferases IEA Gallus gallus 4705 R-GGA-212252 https://reactome.org/PathwayBrowser/#/R-GGA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Gallus gallus 4705 R-GGA-212263 https://reactome.org/PathwayBrowser/#/R-GGA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Gallus gallus 4705 R-GGA-212269 https://reactome.org/PathwayBrowser/#/R-GGA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Gallus gallus 4705 R-GGA-217209 https://reactome.org/PathwayBrowser/#/R-GGA-217209 Generation of a DNA double strand break TAS Gallus gallus 4705 R-GGA-2203480 https://reactome.org/PathwayBrowser/#/R-GGA-2203480 COLEC11 binds ligands IEA Gallus gallus 4705 R-GGA-266204 https://reactome.org/PathwayBrowser/#/R-GGA-266204 Association of HMGB1/HMGB2 with chromatin IEA Gallus gallus 4705 R-GGA-353323 https://reactome.org/PathwayBrowser/#/R-GGA-353323 Ligation of newly synthesized repair patch to incised DNA in GG-NER TAS Gallus gallus 4705 R-GGA-4755536 https://reactome.org/PathwayBrowser/#/R-GGA-4755536 PIAS3 SUMOylates RELA with SUMO3 IEA Gallus gallus 4705 R-GGA-5220959 https://reactome.org/PathwayBrowser/#/R-GGA-5220959 TDG excises 5-formylcytosine IEA Gallus gallus 4705 R-GGA-5221061 https://reactome.org/PathwayBrowser/#/R-GGA-5221061 TDG excises 5-carboxylcytosine IEA Gallus gallus 4705 R-GGA-5358510 https://reactome.org/PathwayBrowser/#/R-GGA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Gallus gallus 4705 R-GGA-5358513 https://reactome.org/PathwayBrowser/#/R-GGA-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Gallus gallus 4705 R-GGA-5358518 https://reactome.org/PathwayBrowser/#/R-GGA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Gallus gallus 4705 R-GGA-5358525 https://reactome.org/PathwayBrowser/#/R-GGA-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Gallus gallus 4705 R-GGA-5358592 https://reactome.org/PathwayBrowser/#/R-GGA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Gallus gallus 4705 R-GGA-5358597 https://reactome.org/PathwayBrowser/#/R-GGA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Gallus gallus 4705 R-GGA-5358599 https://reactome.org/PathwayBrowser/#/R-GGA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Gallus gallus 4705 R-GGA-5358912 https://reactome.org/PathwayBrowser/#/R-GGA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Gallus gallus 4705 R-GGA-5578742 https://reactome.org/PathwayBrowser/#/R-GGA-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Gallus gallus 4705 R-GGA-606287 https://reactome.org/PathwayBrowser/#/R-GGA-606287 RSF complex binds the centromere IEA Gallus gallus 4705 R-GGA-606289 https://reactome.org/PathwayBrowser/#/R-GGA-606289 New CENPA-containing nucleosomes are deposited at the centromere IEA Gallus gallus 4705 R-GGA-606326 https://reactome.org/PathwayBrowser/#/R-GGA-606326 HJURP:CENPA complex localizes to the centromere IEA Gallus gallus 4705 R-GGA-606349 https://reactome.org/PathwayBrowser/#/R-GGA-606349 Mis18 complex binds the centromere IEA Gallus gallus 4705 R-GGA-73718 https://reactome.org/PathwayBrowser/#/R-GGA-73718 UBF-1 Binds rDNA Promoter IEA Gallus gallus 4705 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus 4705 R-GGA-77077 https://reactome.org/PathwayBrowser/#/R-GGA-77077 Capping complex formation IEA Gallus gallus 4705 R-GGA-77078 https://reactome.org/PathwayBrowser/#/R-GGA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Gallus gallus 4705 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus 4705 R-GGA-77083 https://reactome.org/PathwayBrowser/#/R-GGA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Gallus gallus 4705 R-GGA-77085 https://reactome.org/PathwayBrowser/#/R-GGA-77085 Dissociation of transcript with 5'-GMP from GT IEA Gallus gallus 4705 R-HSA-1214188 https://reactome.org/PathwayBrowser/#/R-HSA-1214188 PRDM9 trimethylates histone H3 IEA Homo sapiens 4705 R-HSA-1234167 https://reactome.org/PathwayBrowser/#/R-HSA-1234167 Formation of HIF:CBP:p300 complex at promoters TAS Homo sapiens 4705 R-HSA-1235035 https://reactome.org/PathwayBrowser/#/R-HSA-1235035 Expression of Carbonic Anhydrase IX (CA9) TAS Homo sapiens 4705 R-HSA-1235037 https://reactome.org/PathwayBrowser/#/R-HSA-1235037 Expression of VEGFA TAS Homo sapiens 4705 R-HSA-1235070 https://reactome.org/PathwayBrowser/#/R-HSA-1235070 Expression of Erythropoietin (EPO) TAS Homo sapiens 4705 R-HSA-211239 https://reactome.org/PathwayBrowser/#/R-HSA-211239 Association of DFF40 with chromatin TAS Homo sapiens 4705 R-HSA-211247 https://reactome.org/PathwayBrowser/#/R-HSA-211247 Cleavage of DNA by DFF40 TAS Homo sapiens 4705 R-HSA-212222 https://reactome.org/PathwayBrowser/#/R-HSA-212222 PRC2 recruits DNA methyltransferases TAS Homo sapiens 4705 R-HSA-212252 https://reactome.org/PathwayBrowser/#/R-HSA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin TAS Homo sapiens 4705 R-HSA-212263 https://reactome.org/PathwayBrowser/#/R-HSA-212263 PRC2 trimethylates histone H3 at lysine-27 TAS Homo sapiens 4705 R-HSA-212269 https://reactome.org/PathwayBrowser/#/R-HSA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 TAS Homo sapiens 4705 R-HSA-2203480 https://reactome.org/PathwayBrowser/#/R-HSA-2203480 COLEC11 binds ligands TAS Homo sapiens 4705 R-HSA-266204 https://reactome.org/PathwayBrowser/#/R-HSA-266204 Association of HMGB1/HMGB2 with chromatin TAS Homo sapiens 4705 R-HSA-427336 https://reactome.org/PathwayBrowser/#/R-HSA-427336 TTF1:rRNA promoter:ERCC6:EHMT2 complex dimethylates histone H3 at lysine-9. IEA Homo sapiens 4705 R-HSA-427337 https://reactome.org/PathwayBrowser/#/R-HSA-427337 MBD2 binds methylcytosine in chromatin TAS Homo sapiens 4705 R-HSA-427383 https://reactome.org/PathwayBrowser/#/R-HSA-427383 CBX3 (HP1gamma) binds histone H3 dimethylated at lysine-9 IEA Homo sapiens 4705 R-HSA-427514 https://reactome.org/PathwayBrowser/#/R-HSA-427514 eNoSC deacetylates histone H3 TAS Homo sapiens 4705 R-HSA-427527 https://reactome.org/PathwayBrowser/#/R-HSA-427527 eNoSC dimethylates histone H3 at lysine-9 TAS Homo sapiens 4705 R-HSA-427528 https://reactome.org/PathwayBrowser/#/R-HSA-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) TAS Homo sapiens 4705 R-HSA-433672 https://reactome.org/PathwayBrowser/#/R-HSA-433672 NoRC:HDAC:DNMT deacetylates histone H4 and methylates histone H3 IEA Homo sapiens 4705 R-HSA-4647594 https://reactome.org/PathwayBrowser/#/R-HSA-4647594 SAHF formation TAS Homo sapiens 4705 R-HSA-4755536 https://reactome.org/PathwayBrowser/#/R-HSA-4755536 PIAS3 SUMOylates RELA with SUMO3 TAS Homo sapiens 4705 R-HSA-5220952 https://reactome.org/PathwayBrowser/#/R-HSA-5220952 TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine IEA Homo sapiens 4705 R-HSA-5220959 https://reactome.org/PathwayBrowser/#/R-HSA-5220959 TDG excises 5-formylcytosine TAS Homo sapiens 4705 R-HSA-5220990 https://reactome.org/PathwayBrowser/#/R-HSA-5220990 TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine IEA Homo sapiens 4705 R-HSA-5221014 https://reactome.org/PathwayBrowser/#/R-HSA-5221014 TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine IEA Homo sapiens 4705 R-HSA-5221061 https://reactome.org/PathwayBrowser/#/R-HSA-5221061 TDG excises 5-carboxylcytosine TAS Homo sapiens 4705 R-HSA-5227490 https://reactome.org/PathwayBrowser/#/R-HSA-5227490 NoRC:HDAC:DNMT methylates cytosine of the rRNA genes IEA Homo sapiens 4705 R-HSA-5334097 https://reactome.org/PathwayBrowser/#/R-HSA-5334097 DNMT3B:DNMT3L methylates cytosine in DNA IEA Homo sapiens 4705 R-HSA-5334099 https://reactome.org/PathwayBrowser/#/R-HSA-5334099 UHRF1 binds chromatin with hemimethylated cytosine IEA Homo sapiens 4705 R-HSA-5334151 https://reactome.org/PathwayBrowser/#/R-HSA-5334151 DNMT1 methylates cytosine in hemimethylated DNA IEA Homo sapiens 4705 R-HSA-5334152 https://reactome.org/PathwayBrowser/#/R-HSA-5334152 DNMT3A:DNMT3L methylates cytosine in DNA IEA Homo sapiens 4705 R-HSA-5334160 https://reactome.org/PathwayBrowser/#/R-HSA-5334160 UHRF1:Chromatin binds DNMT1 IEA Homo sapiens 4705 R-HSA-5334164 https://reactome.org/PathwayBrowser/#/R-HSA-5334164 DNMT3B:DNMT3L binds chromatin IEA Homo sapiens 4705 R-HSA-5334179 https://reactome.org/PathwayBrowser/#/R-HSA-5334179 DNMT3A:DNMT3L binds chromatin IEA Homo sapiens 4705 R-HSA-5358510 https://reactome.org/PathwayBrowser/#/R-HSA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA TAS Homo sapiens 4705 R-HSA-5358512 https://reactome.org/PathwayBrowser/#/R-HSA-5358512 MLH1:PMS2 makes single strand incision near insertion/deletion loop of 2 bases or more IEA Homo sapiens 4705 R-HSA-5358513 https://reactome.org/PathwayBrowser/#/R-HSA-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more TAS Homo sapiens 4705 R-HSA-5358518 https://reactome.org/PathwayBrowser/#/R-HSA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch TAS Homo sapiens 4705 R-HSA-5358519 https://reactome.org/PathwayBrowser/#/R-HSA-5358519 MSH2:MSH3 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Homo sapiens 4705 R-HSA-5358525 https://reactome.org/PathwayBrowser/#/R-HSA-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop TAS Homo sapiens 4705 R-HSA-5358545 https://reactome.org/PathwayBrowser/#/R-HSA-5358545 EXO1 interacts with MSH2:MSH3 (MutSbeta) and MLH1:PMS2 (MutLalpha) IEA Homo sapiens 4705 R-HSA-5358579 https://reactome.org/PathwayBrowser/#/R-HSA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap TAS Homo sapiens 4705 R-HSA-5358592 https://reactome.org/PathwayBrowser/#/R-HSA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA TAS Homo sapiens 4705 R-HSA-5358597 https://reactome.org/PathwayBrowser/#/R-HSA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) TAS Homo sapiens 4705 R-HSA-5358599 https://reactome.org/PathwayBrowser/#/R-HSA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch TAS Homo sapiens 4705 R-HSA-5358619 https://reactome.org/PathwayBrowser/#/R-HSA-5358619 EXO1 interacting with MSH2:MSH3 excises DNA strand containing an insertion/deletion loop (IDL) IEA Homo sapiens 4705 R-HSA-5358912 https://reactome.org/PathwayBrowser/#/R-HSA-5358912 MSH2:MSH6 exchanges ADP for ATP TAS Homo sapiens 4705 R-HSA-5358919 https://reactome.org/PathwayBrowser/#/R-HSA-5358919 MSH2:MSH3 exchanges ADP for ATP IEA Homo sapiens 4705 R-HSA-5423632 https://reactome.org/PathwayBrowser/#/R-HSA-5423632 AFXBO binds DNA TAS Homo sapiens 4705 R-HSA-5578742 https://reactome.org/PathwayBrowser/#/R-HSA-5578742 AGO1,2:small RNA complexes interact with chromatin TAS Homo sapiens 4705 R-HSA-606287 https://reactome.org/PathwayBrowser/#/R-HSA-606287 RSF complex binds the centromere TAS Homo sapiens 4705 R-HSA-606289 https://reactome.org/PathwayBrowser/#/R-HSA-606289 New CENPA-containing nucleosomes are deposited at the centromere TAS Homo sapiens 4705 R-HSA-606326 https://reactome.org/PathwayBrowser/#/R-HSA-606326 HJURP:CENPA complex localizes to the centromere TAS Homo sapiens 4705 R-HSA-606349 https://reactome.org/PathwayBrowser/#/R-HSA-606349 Mis18 complex binds the centromere TAS Homo sapiens 4705 R-HSA-73718 https://reactome.org/PathwayBrowser/#/R-HSA-73718 UBF-1 Binds rDNA Promoter TAS Homo sapiens 4705 R-HSA-74986 https://reactome.org/PathwayBrowser/#/R-HSA-74986 Elongation of pre-rRNA transcript TAS Homo sapiens 4705 R-HSA-77077 https://reactome.org/PathwayBrowser/#/R-HSA-77077 Capping complex formation TAS Homo sapiens 4705 R-HSA-77078 https://reactome.org/PathwayBrowser/#/R-HSA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme TAS Homo sapiens 4705 R-HSA-77081 https://reactome.org/PathwayBrowser/#/R-HSA-77081 Formation of the CE:GMP intermediate complex TAS Homo sapiens 4705 R-HSA-77083 https://reactome.org/PathwayBrowser/#/R-HSA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA TAS Homo sapiens 4705 R-HSA-77085 https://reactome.org/PathwayBrowser/#/R-HSA-77085 Dissociation of transcript with 5'-GMP from GT TAS Homo sapiens 4705 R-HSA-77090 https://reactome.org/PathwayBrowser/#/R-HSA-77090 Methylation of GMP-cap by RNA Methyltransferase TAS Homo sapiens 4705 R-HSA-912363 https://reactome.org/PathwayBrowser/#/R-HSA-912363 PRDM9 binds recombination hotspot motifs in DNA IEA Homo sapiens 4705 R-HSA-912368 https://reactome.org/PathwayBrowser/#/R-HSA-912368 SPO11 hydrolyzes DNA forming double-strand breaks IEA Homo sapiens 4705 R-HSA-912450 https://reactome.org/PathwayBrowser/#/R-HSA-912450 ATR Kinase is recruited to unsynapsed regions IEA Homo sapiens 4705 R-HSA-912458 https://reactome.org/PathwayBrowser/#/R-HSA-912458 Formation of meiotic heteroduplex IEA Homo sapiens 4705 R-HSA-912467 https://reactome.org/PathwayBrowser/#/R-HSA-912467 BRCA1 is recruited to unsynapsed regions IEA Homo sapiens 4705 R-HSA-912470 https://reactome.org/PathwayBrowser/#/R-HSA-912470 ATR phosphorylates Histone H2A.X at unsynapsed regions IEA Homo sapiens 4705 R-HSA-9710490 https://reactome.org/PathwayBrowser/#/R-HSA-9710490 The GSDME gene promoter is hypermethylated TAS Homo sapiens 4705 R-HSA-9817458 https://reactome.org/PathwayBrowser/#/R-HSA-9817458 TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 IEA Homo sapiens 4705 R-HSA-9817471 https://reactome.org/PathwayBrowser/#/R-HSA-9817471 DPPA3 binds histone H3K9me2 in chromatin IEA Homo sapiens 4705 R-HSA-9817512 https://reactome.org/PathwayBrowser/#/R-HSA-9817512 UNG (UNG2) and base excision repair remove uridine and 5-methylcytidine from chromatin containing histone H3.3 IEA Homo sapiens 4705 R-HSA-9817513 https://reactome.org/PathwayBrowser/#/R-HSA-9817513 AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine IEA Homo sapiens 4705 R-HSA-9822591 https://reactome.org/PathwayBrowser/#/R-HSA-9822591 TET3 binds chromatin with H3K17me2a and 5-mC:METTL23:STGP4 IEA Homo sapiens 4705 R-HSA-9822597 https://reactome.org/PathwayBrowser/#/R-HSA-9822597 METTL23 and STGP4 (GSE) bind H3.3 dimethylarginine-17 (H3K17me2a) IEA Homo sapiens 4705 R-MMU-1214198 https://reactome.org/PathwayBrowser/#/R-MMU-1214198 Prdm9 Trimethylates Histone H3 at Lysine-4 TAS Mus musculus 4705 R-MMU-1234167 https://reactome.org/PathwayBrowser/#/R-MMU-1234167 Formation of HIF:CBP:p300 complex at promoters IEA Mus musculus 4705 R-MMU-211239 https://reactome.org/PathwayBrowser/#/R-MMU-211239 Association of DFF40 with chromatin IEA Mus musculus 4705 R-MMU-211247 https://reactome.org/PathwayBrowser/#/R-MMU-211247 Cleavage of DNA by DFF40 IEA Mus musculus 4705 R-MMU-212222 https://reactome.org/PathwayBrowser/#/R-MMU-212222 PRC2 recruits DNA methyltransferases IEA Mus musculus 4705 R-MMU-212263 https://reactome.org/PathwayBrowser/#/R-MMU-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Mus musculus 4705 R-MMU-212269 https://reactome.org/PathwayBrowser/#/R-MMU-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Mus musculus 4705 R-MMU-2203480 https://reactome.org/PathwayBrowser/#/R-MMU-2203480 COLEC11 binds ligands IEA Mus musculus 4705 R-MMU-266204 https://reactome.org/PathwayBrowser/#/R-MMU-266204 Association of HMGB1/HMGB2 with chromatin IEA Mus musculus 4705 R-MMU-4647594 https://reactome.org/PathwayBrowser/#/R-MMU-4647594 SAHF formation IEA Mus musculus 4705 R-MMU-4755536 https://reactome.org/PathwayBrowser/#/R-MMU-4755536 PIAS3 SUMOylates RELA with SUMO3 IEA Mus musculus 4705 R-MMU-5220931 https://reactome.org/PathwayBrowser/#/R-MMU-5220931 Tet1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine TAS Mus musculus 4705 R-MMU-5220936 https://reactome.org/PathwayBrowser/#/R-MMU-5220936 Tet1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine TAS Mus musculus 4705 R-MMU-5220944 https://reactome.org/PathwayBrowser/#/R-MMU-5220944 Tet1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine TAS Mus musculus 4705 R-MMU-5220959 https://reactome.org/PathwayBrowser/#/R-MMU-5220959 TDG excises 5-formylcytosine IEA Mus musculus 4705 R-MMU-5221061 https://reactome.org/PathwayBrowser/#/R-MMU-5221061 TDG excises 5-carboxylcytosine IEA Mus musculus 4705 R-MMU-5334134 https://reactome.org/PathwayBrowser/#/R-MMU-5334134 Dnmt3a:Dnmt3l binds chromatin TAS Mus musculus 4705 R-MMU-5336231 https://reactome.org/PathwayBrowser/#/R-MMU-5336231 Uhrf1 binds chromatin with hemimethylC TAS Mus musculus 4705 R-MMU-5336316 https://reactome.org/PathwayBrowser/#/R-MMU-5336316 Dnmt3a:Dnmt3l methylates cytosine in DNA TAS Mus musculus 4705 R-MMU-5336365 https://reactome.org/PathwayBrowser/#/R-MMU-5336365 Uhrf1:Chromatin binds Dnmt1 TAS Mus musculus 4705 R-MMU-5336369 https://reactome.org/PathwayBrowser/#/R-MMU-5336369 Dnmt1 methylates cytosine in hemimethylated DNA TAS Mus musculus 4705 R-MMU-5336380 https://reactome.org/PathwayBrowser/#/R-MMU-5336380 Dnmt3b:Dnmt3l methylates cytosine in DNA TAS Mus musculus 4705 R-MMU-5336403 https://reactome.org/PathwayBrowser/#/R-MMU-5336403 Dnmt3b:Dnmt3l binds chromatin TAS Mus musculus 4705 R-MMU-5358510 https://reactome.org/PathwayBrowser/#/R-MMU-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Mus musculus 4705 R-MMU-5358513 https://reactome.org/PathwayBrowser/#/R-MMU-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Mus musculus 4705 R-MMU-5358518 https://reactome.org/PathwayBrowser/#/R-MMU-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Mus musculus 4705 R-MMU-5358525 https://reactome.org/PathwayBrowser/#/R-MMU-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Mus musculus 4705 R-MMU-5358579 https://reactome.org/PathwayBrowser/#/R-MMU-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Mus musculus 4705 R-MMU-5358592 https://reactome.org/PathwayBrowser/#/R-MMU-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Mus musculus 4705 R-MMU-5358597 https://reactome.org/PathwayBrowser/#/R-MMU-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Mus musculus 4705 R-MMU-5358599 https://reactome.org/PathwayBrowser/#/R-MMU-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Mus musculus 4705 R-MMU-5358912 https://reactome.org/PathwayBrowser/#/R-MMU-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Mus musculus 4705 R-MMU-5605301 https://reactome.org/PathwayBrowser/#/R-MMU-5605301 RNA polymerase II polymerizes primary piRNA transcript TAS Mus musculus 4705 R-MMU-573383 https://reactome.org/PathwayBrowser/#/R-MMU-573383 NoRC:intergenic spacer:Hdac:Dnmt complex methylates cytosine in the rRNA genes TAS Mus musculus 4705 R-MMU-606287 https://reactome.org/PathwayBrowser/#/R-MMU-606287 RSF complex binds the centromere IEA Mus musculus 4705 R-MMU-606326 https://reactome.org/PathwayBrowser/#/R-MMU-606326 HJURP:CENPA complex localizes to the centromere IEA Mus musculus 4705 R-MMU-606349 https://reactome.org/PathwayBrowser/#/R-MMU-606349 Mis18 complex binds the centromere IEA Mus musculus 4705 R-MMU-77077 https://reactome.org/PathwayBrowser/#/R-MMU-77077 Capping complex formation IEA Mus musculus 4705 R-MMU-77078 https://reactome.org/PathwayBrowser/#/R-MMU-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Mus musculus 4705 R-MMU-77081 https://reactome.org/PathwayBrowser/#/R-MMU-77081 Formation of the CE:GMP intermediate complex IEA Mus musculus 4705 R-MMU-77083 https://reactome.org/PathwayBrowser/#/R-MMU-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Mus musculus 4705 R-MMU-77085 https://reactome.org/PathwayBrowser/#/R-MMU-77085 Dissociation of transcript with 5'-GMP from GT IEA Mus musculus 4705 R-MMU-77090 https://reactome.org/PathwayBrowser/#/R-MMU-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Mus musculus 4705 R-MMU-912344 https://reactome.org/PathwayBrowser/#/R-MMU-912344 Formation of Double-strand Break in DNA by Spo11 TAS Mus musculus 4705 R-MMU-912383 https://reactome.org/PathwayBrowser/#/R-MMU-912383 Prdm9 Binds Recombination Hotspot Motifs in DNA TAS Mus musculus 4705 R-MMU-912423 https://reactome.org/PathwayBrowser/#/R-MMU-912423 Atr Phosphorylates Histone H2A.X at Unsynapsed Regions TAS Mus musculus 4705 R-MMU-912431 https://reactome.org/PathwayBrowser/#/R-MMU-912431 Formation of Meiotic Heteroduplex TAS Mus musculus 4705 R-MMU-912449 https://reactome.org/PathwayBrowser/#/R-MMU-912449 Recruitment of Atr Kinase to Unsynapsed Regions TAS Mus musculus 4705 R-MMU-912468 https://reactome.org/PathwayBrowser/#/R-MMU-912468 Recruitment of Brca1 to Unsynapsed Regions TAS Mus musculus 4705 R-MMU-9817463 https://reactome.org/PathwayBrowser/#/R-MMU-9817463 Tet3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 dimethylated on lysine-9 TAS Mus musculus 4705 R-MMU-9817490 https://reactome.org/PathwayBrowser/#/R-MMU-9817490 Dppa3 binds histone H3K9me2 in chromatin TAS Mus musculus 4705 R-MMU-9817520 https://reactome.org/PathwayBrowser/#/R-MMU-9817520 Aicda deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine TAS Mus musculus 4705 R-MMU-9817522 https://reactome.org/PathwayBrowser/#/R-MMU-9817522 Ung (Ung2) and base excision repair remove uridine and 5-methylcytidine from chromatin containing histone H3.3 TAS Mus musculus 4705 R-MMU-9822631 https://reactome.org/PathwayBrowser/#/R-MMU-9822631 Tet3 binds chromatin with H3K17me2a and 5-mC:Mettl23:Stgp4 TAS Mus musculus 4705 R-MMU-9822637 https://reactome.org/PathwayBrowser/#/R-MMU-9822637 Mettl23 and Stgp4 (Gse) bind chromatin with H3.3 dimethylarginine-17 TAS Mus musculus 4705 R-PFA-266204 https://reactome.org/PathwayBrowser/#/R-PFA-266204 Association of HMGB1/HMGB2 with chromatin IEA Plasmodium falciparum 4705 R-PFA-5358510 https://reactome.org/PathwayBrowser/#/R-PFA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Plasmodium falciparum 4705 R-PFA-5358518 https://reactome.org/PathwayBrowser/#/R-PFA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Plasmodium falciparum 4705 R-PFA-5358525 https://reactome.org/PathwayBrowser/#/R-PFA-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Plasmodium falciparum 4705 R-PFA-5358592 https://reactome.org/PathwayBrowser/#/R-PFA-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Plasmodium falciparum 4705 R-PFA-5358597 https://reactome.org/PathwayBrowser/#/R-PFA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Plasmodium falciparum 4705 R-PFA-5358599 https://reactome.org/PathwayBrowser/#/R-PFA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Plasmodium falciparum 4705 R-PFA-5358912 https://reactome.org/PathwayBrowser/#/R-PFA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Plasmodium falciparum 4705 R-PFA-77077 https://reactome.org/PathwayBrowser/#/R-PFA-77077 Capping complex formation IEA Plasmodium falciparum 4705 R-PFA-77078 https://reactome.org/PathwayBrowser/#/R-PFA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Plasmodium falciparum 4705 R-PFA-77081 https://reactome.org/PathwayBrowser/#/R-PFA-77081 Formation of the CE:GMP intermediate complex IEA Plasmodium falciparum 4705 R-PFA-77083 https://reactome.org/PathwayBrowser/#/R-PFA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Plasmodium falciparum 4705 R-PFA-77085 https://reactome.org/PathwayBrowser/#/R-PFA-77085 Dissociation of transcript with 5'-GMP from GT IEA Plasmodium falciparum 4705 R-RNO-1234167 https://reactome.org/PathwayBrowser/#/R-RNO-1234167 Formation of HIF:CBP:p300 complex at promoters IEA Rattus norvegicus 4705 R-RNO-211239 https://reactome.org/PathwayBrowser/#/R-RNO-211239 Association of DFF40 with chromatin IEA Rattus norvegicus 4705 R-RNO-211247 https://reactome.org/PathwayBrowser/#/R-RNO-211247 Cleavage of DNA by DFF40 IEA Rattus norvegicus 4705 R-RNO-212222 https://reactome.org/PathwayBrowser/#/R-RNO-212222 PRC2 recruits DNA methyltransferases IEA Rattus norvegicus 4705 R-RNO-212252 https://reactome.org/PathwayBrowser/#/R-RNO-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Rattus norvegicus 4705 R-RNO-212263 https://reactome.org/PathwayBrowser/#/R-RNO-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Rattus norvegicus 4705 R-RNO-212269 https://reactome.org/PathwayBrowser/#/R-RNO-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Rattus norvegicus 4705 R-RNO-266204 https://reactome.org/PathwayBrowser/#/R-RNO-266204 Association of HMGB1/HMGB2 with chromatin IEA Rattus norvegicus 4705 R-RNO-427337 https://reactome.org/PathwayBrowser/#/R-RNO-427337 MBD2 binds methylcytosine in chromatin IEA Rattus norvegicus 4705 R-RNO-427514 https://reactome.org/PathwayBrowser/#/R-RNO-427514 eNoSC deacetylates histone H3 IEA Rattus norvegicus 4705 R-RNO-427527 https://reactome.org/PathwayBrowser/#/R-RNO-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Rattus norvegicus 4705 R-RNO-427528 https://reactome.org/PathwayBrowser/#/R-RNO-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Rattus norvegicus 4705 R-RNO-4755536 https://reactome.org/PathwayBrowser/#/R-RNO-4755536 PIAS3 SUMOylates RELA with SUMO3 IEA Rattus norvegicus 4705 R-RNO-5220959 https://reactome.org/PathwayBrowser/#/R-RNO-5220959 TDG excises 5-formylcytosine IEA Rattus norvegicus 4705 R-RNO-5221061 https://reactome.org/PathwayBrowser/#/R-RNO-5221061 TDG excises 5-carboxylcytosine IEA Rattus norvegicus 4705 R-RNO-5358510 https://reactome.org/PathwayBrowser/#/R-RNO-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Rattus norvegicus 4705 R-RNO-5358518 https://reactome.org/PathwayBrowser/#/R-RNO-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Rattus norvegicus 4705 R-RNO-5358525 https://reactome.org/PathwayBrowser/#/R-RNO-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Rattus norvegicus 4705 R-RNO-5358579 https://reactome.org/PathwayBrowser/#/R-RNO-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Rattus norvegicus 4705 R-RNO-5358592 https://reactome.org/PathwayBrowser/#/R-RNO-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Rattus norvegicus 4705 R-RNO-5358597 https://reactome.org/PathwayBrowser/#/R-RNO-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Rattus norvegicus 4705 R-RNO-5358599 https://reactome.org/PathwayBrowser/#/R-RNO-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Rattus norvegicus 4705 R-RNO-5358912 https://reactome.org/PathwayBrowser/#/R-RNO-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Rattus norvegicus 4705 R-RNO-5578742 https://reactome.org/PathwayBrowser/#/R-RNO-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Rattus norvegicus 4705 R-RNO-606287 https://reactome.org/PathwayBrowser/#/R-RNO-606287 RSF complex binds the centromere IEA Rattus norvegicus 4705 R-RNO-606326 https://reactome.org/PathwayBrowser/#/R-RNO-606326 HJURP:CENPA complex localizes to the centromere IEA Rattus norvegicus 4705 R-RNO-606349 https://reactome.org/PathwayBrowser/#/R-RNO-606349 Mis18 complex binds the centromere IEA Rattus norvegicus 4705 R-RNO-73718 https://reactome.org/PathwayBrowser/#/R-RNO-73718 UBF-1 Binds rDNA Promoter IEA Rattus norvegicus 4705 R-RNO-74986 https://reactome.org/PathwayBrowser/#/R-RNO-74986 Elongation of pre-rRNA transcript IEA Rattus norvegicus 4705 R-RNO-77077 https://reactome.org/PathwayBrowser/#/R-RNO-77077 Capping complex formation IEA Rattus norvegicus 4705 R-RNO-77078 https://reactome.org/PathwayBrowser/#/R-RNO-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Rattus norvegicus 4705 R-RNO-77081 https://reactome.org/PathwayBrowser/#/R-RNO-77081 Formation of the CE:GMP intermediate complex IEA Rattus norvegicus 4705 R-RNO-77083 https://reactome.org/PathwayBrowser/#/R-RNO-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Rattus norvegicus 4705 R-RNO-77085 https://reactome.org/PathwayBrowser/#/R-RNO-77085 Dissociation of transcript with 5'-GMP from GT IEA Rattus norvegicus 4705 R-RNO-77090 https://reactome.org/PathwayBrowser/#/R-RNO-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Rattus norvegicus 4705 R-SCE-266204 https://reactome.org/PathwayBrowser/#/R-SCE-266204 Association of HMGB1/HMGB2 with chromatin IEA Saccharomyces cerevisiae 4705 R-SCE-427514 https://reactome.org/PathwayBrowser/#/R-SCE-427514 eNoSC deacetylates histone H3 IEA Saccharomyces cerevisiae 4705 R-SCE-427527 https://reactome.org/PathwayBrowser/#/R-SCE-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Saccharomyces cerevisiae 4705 R-SCE-5358510 https://reactome.org/PathwayBrowser/#/R-SCE-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Saccharomyces cerevisiae 4705 R-SCE-5358513 https://reactome.org/PathwayBrowser/#/R-SCE-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Saccharomyces cerevisiae 4705 R-SCE-5358518 https://reactome.org/PathwayBrowser/#/R-SCE-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Saccharomyces cerevisiae 4705 R-SCE-5358525 https://reactome.org/PathwayBrowser/#/R-SCE-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Saccharomyces cerevisiae 4705 R-SCE-5358592 https://reactome.org/PathwayBrowser/#/R-SCE-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Saccharomyces cerevisiae 4705 R-SCE-5358597 https://reactome.org/PathwayBrowser/#/R-SCE-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Saccharomyces cerevisiae 4705 R-SCE-5358912 https://reactome.org/PathwayBrowser/#/R-SCE-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Saccharomyces cerevisiae 4705 R-SCE-74986 https://reactome.org/PathwayBrowser/#/R-SCE-74986 Elongation of pre-rRNA transcript IEA Saccharomyces cerevisiae 4705 R-SCE-77077 https://reactome.org/PathwayBrowser/#/R-SCE-77077 Capping complex formation IEA Saccharomyces cerevisiae 4705 R-SCE-77078 https://reactome.org/PathwayBrowser/#/R-SCE-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Saccharomyces cerevisiae 4705 R-SCE-77081 https://reactome.org/PathwayBrowser/#/R-SCE-77081 Formation of the CE:GMP intermediate complex IEA Saccharomyces cerevisiae 4705 R-SCE-77083 https://reactome.org/PathwayBrowser/#/R-SCE-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Saccharomyces cerevisiae 4705 R-SCE-77085 https://reactome.org/PathwayBrowser/#/R-SCE-77085 Dissociation of transcript with 5'-GMP from GT IEA Saccharomyces cerevisiae 4705 R-SCE-77090 https://reactome.org/PathwayBrowser/#/R-SCE-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Saccharomyces cerevisiae 4705 R-SPO-266204 https://reactome.org/PathwayBrowser/#/R-SPO-266204 Association of HMGB1/HMGB2 with chromatin IEA Schizosaccharomyces pombe 4705 R-SPO-427514 https://reactome.org/PathwayBrowser/#/R-SPO-427514 eNoSC deacetylates histone H3 IEA Schizosaccharomyces pombe 4705 R-SPO-427527 https://reactome.org/PathwayBrowser/#/R-SPO-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Schizosaccharomyces pombe 4705 R-SPO-5220959 https://reactome.org/PathwayBrowser/#/R-SPO-5220959 TDG excises 5-formylcytosine IEA Schizosaccharomyces pombe 4705 R-SPO-5221061 https://reactome.org/PathwayBrowser/#/R-SPO-5221061 TDG excises 5-carboxylcytosine IEA Schizosaccharomyces pombe 4705 R-SPO-5358510 https://reactome.org/PathwayBrowser/#/R-SPO-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Schizosaccharomyces pombe 4705 R-SPO-5358513 https://reactome.org/PathwayBrowser/#/R-SPO-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Schizosaccharomyces pombe 4705 R-SPO-5358518 https://reactome.org/PathwayBrowser/#/R-SPO-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Schizosaccharomyces pombe 4705 R-SPO-5358525 https://reactome.org/PathwayBrowser/#/R-SPO-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Schizosaccharomyces pombe 4705 R-SPO-5358579 https://reactome.org/PathwayBrowser/#/R-SPO-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Schizosaccharomyces pombe 4705 R-SPO-5358592 https://reactome.org/PathwayBrowser/#/R-SPO-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Schizosaccharomyces pombe 4705 R-SPO-5358597 https://reactome.org/PathwayBrowser/#/R-SPO-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Schizosaccharomyces pombe 4705 R-SPO-5358599 https://reactome.org/PathwayBrowser/#/R-SPO-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Schizosaccharomyces pombe 4705 R-SPO-5358912 https://reactome.org/PathwayBrowser/#/R-SPO-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Schizosaccharomyces pombe 4705 R-SPO-5578742 https://reactome.org/PathwayBrowser/#/R-SPO-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Schizosaccharomyces pombe 4705 R-SPO-74986 https://reactome.org/PathwayBrowser/#/R-SPO-74986 Elongation of pre-rRNA transcript IEA Schizosaccharomyces pombe 4705 R-SPO-77077 https://reactome.org/PathwayBrowser/#/R-SPO-77077 Capping complex formation IEA Schizosaccharomyces pombe 4705 R-SPO-77078 https://reactome.org/PathwayBrowser/#/R-SPO-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Schizosaccharomyces pombe 4705 R-SPO-77081 https://reactome.org/PathwayBrowser/#/R-SPO-77081 Formation of the CE:GMP intermediate complex IEA Schizosaccharomyces pombe 4705 R-SPO-77083 https://reactome.org/PathwayBrowser/#/R-SPO-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Schizosaccharomyces pombe 4705 R-SPO-77085 https://reactome.org/PathwayBrowser/#/R-SPO-77085 Dissociation of transcript with 5'-GMP from GT IEA Schizosaccharomyces pombe 4705 R-SPO-77090 https://reactome.org/PathwayBrowser/#/R-SPO-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Schizosaccharomyces pombe 4705 R-SSC-1234167 https://reactome.org/PathwayBrowser/#/R-SSC-1234167 Formation of HIF:CBP:p300 complex at promoters IEA Sus scrofa 4705 R-SSC-211239 https://reactome.org/PathwayBrowser/#/R-SSC-211239 Association of DFF40 with chromatin IEA Sus scrofa 4705 R-SSC-211247 https://reactome.org/PathwayBrowser/#/R-SSC-211247 Cleavage of DNA by DFF40 IEA Sus scrofa 4705 R-SSC-212222 https://reactome.org/PathwayBrowser/#/R-SSC-212222 PRC2 recruits DNA methyltransferases IEA Sus scrofa 4705 R-SSC-212252 https://reactome.org/PathwayBrowser/#/R-SSC-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Sus scrofa 4705 R-SSC-212263 https://reactome.org/PathwayBrowser/#/R-SSC-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Sus scrofa 4705 R-SSC-212269 https://reactome.org/PathwayBrowser/#/R-SSC-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Sus scrofa 4705 R-SSC-2203480 https://reactome.org/PathwayBrowser/#/R-SSC-2203480 COLEC11 binds ligands IEA Sus scrofa 4705 R-SSC-266204 https://reactome.org/PathwayBrowser/#/R-SSC-266204 Association of HMGB1/HMGB2 with chromatin IEA Sus scrofa 4705 R-SSC-427337 https://reactome.org/PathwayBrowser/#/R-SSC-427337 MBD2 binds methylcytosine in chromatin IEA Sus scrofa 4705 R-SSC-427514 https://reactome.org/PathwayBrowser/#/R-SSC-427514 eNoSC deacetylates histone H3 IEA Sus scrofa 4705 R-SSC-427527 https://reactome.org/PathwayBrowser/#/R-SSC-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Sus scrofa 4705 R-SSC-427528 https://reactome.org/PathwayBrowser/#/R-SSC-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Sus scrofa 4705 R-SSC-4647594 https://reactome.org/PathwayBrowser/#/R-SSC-4647594 SAHF formation IEA Sus scrofa 4705 R-SSC-4755536 https://reactome.org/PathwayBrowser/#/R-SSC-4755536 PIAS3 SUMOylates RELA with SUMO3 IEA Sus scrofa 4705 R-SSC-5220959 https://reactome.org/PathwayBrowser/#/R-SSC-5220959 TDG excises 5-formylcytosine IEA Sus scrofa 4705 R-SSC-5221061 https://reactome.org/PathwayBrowser/#/R-SSC-5221061 TDG excises 5-carboxylcytosine IEA Sus scrofa 4705 R-SSC-5358510 https://reactome.org/PathwayBrowser/#/R-SSC-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Sus scrofa 4705 R-SSC-5358513 https://reactome.org/PathwayBrowser/#/R-SSC-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Sus scrofa 4705 R-SSC-5358518 https://reactome.org/PathwayBrowser/#/R-SSC-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Sus scrofa 4705 R-SSC-5358525 https://reactome.org/PathwayBrowser/#/R-SSC-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Sus scrofa 4705 R-SSC-5358579 https://reactome.org/PathwayBrowser/#/R-SSC-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Sus scrofa 4705 R-SSC-5358592 https://reactome.org/PathwayBrowser/#/R-SSC-5358592 DNA ligase I ligates single stranded nick in double stranded DNA IEA Sus scrofa 4705 R-SSC-5358597 https://reactome.org/PathwayBrowser/#/R-SSC-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Sus scrofa 4705 R-SSC-5358599 https://reactome.org/PathwayBrowser/#/R-SSC-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Sus scrofa 4705 R-SSC-5358912 https://reactome.org/PathwayBrowser/#/R-SSC-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Sus scrofa 4705 R-SSC-5578742 https://reactome.org/PathwayBrowser/#/R-SSC-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Sus scrofa 4705 R-SSC-606287 https://reactome.org/PathwayBrowser/#/R-SSC-606287 RSF complex binds the centromere IEA Sus scrofa 4705 R-SSC-606326 https://reactome.org/PathwayBrowser/#/R-SSC-606326 HJURP:CENPA complex localizes to the centromere IEA Sus scrofa 4705 R-SSC-606349 https://reactome.org/PathwayBrowser/#/R-SSC-606349 Mis18 complex binds the centromere IEA Sus scrofa 4705 R-SSC-73718 https://reactome.org/PathwayBrowser/#/R-SSC-73718 UBF-1 Binds rDNA Promoter IEA Sus scrofa 4705 R-SSC-74986 https://reactome.org/PathwayBrowser/#/R-SSC-74986 Elongation of pre-rRNA transcript IEA Sus scrofa 4705 R-SSC-77077 https://reactome.org/PathwayBrowser/#/R-SSC-77077 Capping complex formation IEA Sus scrofa 4705 R-SSC-77078 https://reactome.org/PathwayBrowser/#/R-SSC-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Sus scrofa 4705 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa 4705 R-SSC-77083 https://reactome.org/PathwayBrowser/#/R-SSC-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Sus scrofa 4705 R-SSC-77085 https://reactome.org/PathwayBrowser/#/R-SSC-77085 Dissociation of transcript with 5'-GMP from GT IEA Sus scrofa 4705 R-SSC-77090 https://reactome.org/PathwayBrowser/#/R-SSC-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Sus scrofa 4705 R-XTR-212222 https://reactome.org/PathwayBrowser/#/R-XTR-212222 PRC2 recruits DNA methyltransferases IEA Xenopus tropicalis 4705 R-XTR-212252 https://reactome.org/PathwayBrowser/#/R-XTR-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Xenopus tropicalis 4705 R-XTR-212263 https://reactome.org/PathwayBrowser/#/R-XTR-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Xenopus tropicalis 4705 R-XTR-212269 https://reactome.org/PathwayBrowser/#/R-XTR-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Xenopus tropicalis 4705 R-XTR-266204 https://reactome.org/PathwayBrowser/#/R-XTR-266204 Association of HMGB1/HMGB2 with chromatin IEA Xenopus tropicalis 4705 R-XTR-427337 https://reactome.org/PathwayBrowser/#/R-XTR-427337 MBD2 binds methylcytosine in chromatin IEA Xenopus tropicalis 4705 R-XTR-5220959 https://reactome.org/PathwayBrowser/#/R-XTR-5220959 TDG excises 5-formylcytosine IEA Xenopus tropicalis 4705 R-XTR-5221061 https://reactome.org/PathwayBrowser/#/R-XTR-5221061 TDG excises 5-carboxylcytosine IEA Xenopus tropicalis 4705 R-XTR-5578742 https://reactome.org/PathwayBrowser/#/R-XTR-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Xenopus tropicalis 4705 R-XTR-606349 https://reactome.org/PathwayBrowser/#/R-XTR-606349 Mis18 complex binds the centromere IEA Xenopus tropicalis 4705 R-XTR-73718 https://reactome.org/PathwayBrowser/#/R-XTR-73718 UBF-1 Binds rDNA Promoter IEA Xenopus tropicalis 4705 R-XTR-77077 https://reactome.org/PathwayBrowser/#/R-XTR-77077 Capping complex formation IEA Xenopus tropicalis 4705 R-XTR-77078 https://reactome.org/PathwayBrowser/#/R-XTR-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Xenopus tropicalis 4705 R-XTR-77081 https://reactome.org/PathwayBrowser/#/R-XTR-77081 Formation of the CE:GMP intermediate complex IEA Xenopus tropicalis 4705 R-XTR-77083 https://reactome.org/PathwayBrowser/#/R-XTR-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Xenopus tropicalis 4705 R-XTR-77085 https://reactome.org/PathwayBrowser/#/R-XTR-77085 Dissociation of transcript with 5'-GMP from GT IEA Xenopus tropicalis 4708 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 4708 R-BTA-9617370 https://reactome.org/PathwayBrowser/#/R-BTA-9617370 α1-antagonists bind ADRA1A,B,D IEA Bos taurus 4708 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 4708 R-CEL-9617370 https://reactome.org/PathwayBrowser/#/R-CEL-9617370 α1-antagonists bind ADRA1A,B,D IEA Caenorhabditis elegans 4708 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 4708 R-CFA-9617370 https://reactome.org/PathwayBrowser/#/R-CFA-9617370 α1-antagonists bind ADRA1A,B,D IEA Canis familiaris 4708 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 4708 R-DME-9617370 https://reactome.org/PathwayBrowser/#/R-DME-9617370 α1-antagonists bind ADRA1A,B,D IEA Drosophila melanogaster 4708 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 4708 R-DRE-9617370 https://reactome.org/PathwayBrowser/#/R-DRE-9617370 α1-antagonists bind ADRA1A,B,D IEA Danio rerio 4708 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 4708 R-GGA-9617370 https://reactome.org/PathwayBrowser/#/R-GGA-9617370 α1-antagonists bind ADRA1A,B,D IEA Gallus gallus 4708 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 4708 R-HSA-9617370 https://reactome.org/PathwayBrowser/#/R-HSA-9617370 α1-antagonists bind ADRA1A,B,D TAS Homo sapiens 4708 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 4708 R-MMU-9617370 https://reactome.org/PathwayBrowser/#/R-MMU-9617370 α1-antagonists bind ADRA1A,B,D IEA Mus musculus 4708 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 4708 R-RNO-9617370 https://reactome.org/PathwayBrowser/#/R-RNO-9617370 α1-antagonists bind ADRA1A,B,D IEA Rattus norvegicus 4708 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 4708 R-SSC-9617370 https://reactome.org/PathwayBrowser/#/R-SSC-9617370 α1-antagonists bind ADRA1A,B,D IEA Sus scrofa 4708 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 4708 R-XTR-9617370 https://reactome.org/PathwayBrowser/#/R-XTR-9617370 α1-antagonists bind ADRA1A,B,D IEA Xenopus tropicalis 47097 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 47097 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 47097 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 47097 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 47097 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 47097 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 47097 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 47097 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 47097 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 47097 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 47097 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 47097 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 47097 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 47097 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 47097 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 47097 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 47097 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 47097 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 47097 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 47097 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 47097 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 4712 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 4712 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 4712 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 4712 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 4712 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 4712 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 4712 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 4712 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 4712 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 4712 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 4712 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 47266 R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 47266 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 47266 R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 47266 R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 47266 R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 47266 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 47266 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 47266 R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 47266 R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 47266 R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 47266 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 47266 R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 47499 R-BTA-549304 https://reactome.org/PathwayBrowser/#/R-BTA-549304 OCT3 mediates renal clearance of organic cations IEA Bos taurus 47499 R-BTA-561072 https://reactome.org/PathwayBrowser/#/R-BTA-561072 OCT3 mediates renal uptake of organic cations IEA Bos taurus 47499 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans 47499 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans 47499 R-CFA-549304 https://reactome.org/PathwayBrowser/#/R-CFA-549304 OCT3 mediates renal clearance of organic cations IEA Canis familiaris 47499 R-CFA-561072 https://reactome.org/PathwayBrowser/#/R-CFA-561072 OCT3 mediates renal uptake of organic cations IEA Canis familiaris 47499 R-DME-549304 https://reactome.org/PathwayBrowser/#/R-DME-549304 OCT3 mediates renal clearance of organic cations IEA Drosophila melanogaster 47499 R-DME-561072 https://reactome.org/PathwayBrowser/#/R-DME-561072 OCT3 mediates renal uptake of organic cations IEA Drosophila melanogaster 47499 R-DRE-549304 https://reactome.org/PathwayBrowser/#/R-DRE-549304 OCT3 mediates renal clearance of organic cations IEA Danio rerio 47499 R-DRE-561072 https://reactome.org/PathwayBrowser/#/R-DRE-561072 OCT3 mediates renal uptake of organic cations IEA Danio rerio 47499 R-GGA-549304 https://reactome.org/PathwayBrowser/#/R-GGA-549304 OCT3 mediates renal clearance of organic cations IEA Gallus gallus 47499 R-GGA-561072 https://reactome.org/PathwayBrowser/#/R-GGA-561072 OCT3 mediates renal uptake of organic cations IEA Gallus gallus 47499 R-HSA-549304 https://reactome.org/PathwayBrowser/#/R-HSA-549304 OCT3 mediates renal clearance of organic cations TAS Homo sapiens 47499 R-HSA-561072 https://reactome.org/PathwayBrowser/#/R-HSA-561072 OCT3 mediates renal uptake of organic cations TAS Homo sapiens 47499 R-MMU-549304 https://reactome.org/PathwayBrowser/#/R-MMU-549304 OCT3 mediates renal clearance of organic cations IEA Mus musculus 47499 R-MMU-561072 https://reactome.org/PathwayBrowser/#/R-MMU-561072 OCT3 mediates renal uptake of organic cations IEA Mus musculus 47499 R-RNO-549304 https://reactome.org/PathwayBrowser/#/R-RNO-549304 OCT3 mediates renal clearance of organic cations IEA Rattus norvegicus 47499 R-RNO-561072 https://reactome.org/PathwayBrowser/#/R-RNO-561072 OCT3 mediates renal uptake of organic cations IEA Rattus norvegicus 47499 R-SSC-549304 https://reactome.org/PathwayBrowser/#/R-SSC-549304 OCT3 mediates renal clearance of organic cations IEA Sus scrofa 47499 R-SSC-561072 https://reactome.org/PathwayBrowser/#/R-SSC-561072 OCT3 mediates renal uptake of organic cations IEA Sus scrofa 4753 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 4753 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 4753 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 4753 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 4753 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 4753 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 4753 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 4753 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 4753 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 4753 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 4753 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 4753 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 4753 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 4753 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 4753 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 47575 R-BTA-9692376 https://reactome.org/PathwayBrowser/#/R-BTA-9692376 BCL2 binds BCL2 antagonists IEA Bos taurus 47575 R-CEL-9692376 https://reactome.org/PathwayBrowser/#/R-CEL-9692376 BCL2 binds BCL2 antagonists IEA Caenorhabditis elegans 47575 R-CFA-9692376 https://reactome.org/PathwayBrowser/#/R-CFA-9692376 BCL2 binds BCL2 antagonists IEA Canis familiaris 47575 R-DRE-9692376 https://reactome.org/PathwayBrowser/#/R-DRE-9692376 BCL2 binds BCL2 antagonists IEA Danio rerio 47575 R-GGA-9692376 https://reactome.org/PathwayBrowser/#/R-GGA-9692376 BCL2 binds BCL2 antagonists IEA Gallus gallus 47575 R-HSA-9692376 https://reactome.org/PathwayBrowser/#/R-HSA-9692376 BCL2 binds BCL2 antagonists TAS Homo sapiens 47575 R-MMU-9692376 https://reactome.org/PathwayBrowser/#/R-MMU-9692376 BCL2 binds BCL2 antagonists IEA Mus musculus 47575 R-SSC-9692376 https://reactome.org/PathwayBrowser/#/R-SSC-9692376 BCL2 binds BCL2 antagonists IEA Sus scrofa 47575 R-XTR-9692376 https://reactome.org/PathwayBrowser/#/R-XTR-9692376 BCL2 binds BCL2 antagonists IEA Xenopus tropicalis 47781 R-BTA-549304 https://reactome.org/PathwayBrowser/#/R-BTA-549304 OCT3 mediates renal clearance of organic cations IEA Bos taurus 47781 R-BTA-561072 https://reactome.org/PathwayBrowser/#/R-BTA-561072 OCT3 mediates renal uptake of organic cations IEA Bos taurus 47781 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans 47781 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans 47781 R-CFA-549304 https://reactome.org/PathwayBrowser/#/R-CFA-549304 OCT3 mediates renal clearance of organic cations IEA Canis familiaris 47781 R-CFA-561072 https://reactome.org/PathwayBrowser/#/R-CFA-561072 OCT3 mediates renal uptake of organic cations IEA Canis familiaris 47781 R-DME-549304 https://reactome.org/PathwayBrowser/#/R-DME-549304 OCT3 mediates renal clearance of organic cations IEA Drosophila melanogaster 47781 R-DME-561072 https://reactome.org/PathwayBrowser/#/R-DME-561072 OCT3 mediates renal uptake of organic cations IEA Drosophila melanogaster 47781 R-DRE-549304 https://reactome.org/PathwayBrowser/#/R-DRE-549304 OCT3 mediates renal clearance of organic cations IEA Danio rerio 47781 R-DRE-561072 https://reactome.org/PathwayBrowser/#/R-DRE-561072 OCT3 mediates renal uptake of organic cations IEA Danio rerio 47781 R-GGA-549304 https://reactome.org/PathwayBrowser/#/R-GGA-549304 OCT3 mediates renal clearance of organic cations IEA Gallus gallus 47781 R-GGA-561072 https://reactome.org/PathwayBrowser/#/R-GGA-561072 OCT3 mediates renal uptake of organic cations IEA Gallus gallus 47781 R-HSA-549304 https://reactome.org/PathwayBrowser/#/R-HSA-549304 OCT3 mediates renal clearance of organic cations TAS Homo sapiens 47781 R-HSA-561072 https://reactome.org/PathwayBrowser/#/R-HSA-561072 OCT3 mediates renal uptake of organic cations TAS Homo sapiens 47781 R-MMU-549304 https://reactome.org/PathwayBrowser/#/R-MMU-549304 OCT3 mediates renal clearance of organic cations IEA Mus musculus 47781 R-MMU-561072 https://reactome.org/PathwayBrowser/#/R-MMU-561072 OCT3 mediates renal uptake of organic cations IEA Mus musculus 47781 R-RNO-549304 https://reactome.org/PathwayBrowser/#/R-RNO-549304 OCT3 mediates renal clearance of organic cations IEA Rattus norvegicus 47781 R-RNO-561072 https://reactome.org/PathwayBrowser/#/R-RNO-561072 OCT3 mediates renal uptake of organic cations IEA Rattus norvegicus 47781 R-SSC-549304 https://reactome.org/PathwayBrowser/#/R-SSC-549304 OCT3 mediates renal clearance of organic cations IEA Sus scrofa 47781 R-SSC-561072 https://reactome.org/PathwayBrowser/#/R-SSC-561072 OCT3 mediates renal uptake of organic cations IEA Sus scrofa 47807 R-BTA-9712274 https://reactome.org/PathwayBrowser/#/R-BTA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Bos taurus 47807 R-BTA-9755505 https://reactome.org/PathwayBrowser/#/R-BTA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Bos taurus 47807 R-CEL-9712274 https://reactome.org/PathwayBrowser/#/R-CEL-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Caenorhabditis elegans 47807 R-CEL-9755505 https://reactome.org/PathwayBrowser/#/R-CEL-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Caenorhabditis elegans 47807 R-CFA-9712274 https://reactome.org/PathwayBrowser/#/R-CFA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Canis familiaris 47807 R-CFA-9755505 https://reactome.org/PathwayBrowser/#/R-CFA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Canis familiaris 47807 R-DDI-9712274 https://reactome.org/PathwayBrowser/#/R-DDI-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Dictyostelium discoideum 47807 R-DDI-9755505 https://reactome.org/PathwayBrowser/#/R-DDI-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Dictyostelium discoideum 47807 R-DME-9712274 https://reactome.org/PathwayBrowser/#/R-DME-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Drosophila melanogaster 47807 R-DME-9755505 https://reactome.org/PathwayBrowser/#/R-DME-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Drosophila melanogaster 47807 R-DRE-9712274 https://reactome.org/PathwayBrowser/#/R-DRE-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Danio rerio 47807 R-DRE-9755505 https://reactome.org/PathwayBrowser/#/R-DRE-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Danio rerio 47807 R-GGA-9712274 https://reactome.org/PathwayBrowser/#/R-GGA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Gallus gallus 47807 R-GGA-9755505 https://reactome.org/PathwayBrowser/#/R-GGA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Gallus gallus 47807 R-HSA-9712274 https://reactome.org/PathwayBrowser/#/R-HSA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 TAS Homo sapiens 47807 R-HSA-9755505 https://reactome.org/PathwayBrowser/#/R-HSA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 TAS Homo sapiens 47807 R-MMU-9712274 https://reactome.org/PathwayBrowser/#/R-MMU-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Mus musculus 47807 R-MMU-9755505 https://reactome.org/PathwayBrowser/#/R-MMU-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Mus musculus 47807 R-RNO-9712274 https://reactome.org/PathwayBrowser/#/R-RNO-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Rattus norvegicus 47807 R-RNO-9755505 https://reactome.org/PathwayBrowser/#/R-RNO-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Rattus norvegicus 47807 R-SSC-9712274 https://reactome.org/PathwayBrowser/#/R-SSC-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Sus scrofa 47807 R-SSC-9755505 https://reactome.org/PathwayBrowser/#/R-SSC-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Sus scrofa 47807 R-XTR-9712274 https://reactome.org/PathwayBrowser/#/R-XTR-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Xenopus tropicalis 47807 R-XTR-9755505 https://reactome.org/PathwayBrowser/#/R-XTR-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Xenopus tropicalis 47823 R-BTA-8936442 https://reactome.org/PathwayBrowser/#/R-BTA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Bos taurus 47823 R-CEL-8936442 https://reactome.org/PathwayBrowser/#/R-CEL-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Caenorhabditis elegans 47823 R-CFA-8936442 https://reactome.org/PathwayBrowser/#/R-CFA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Canis familiaris 47823 R-DDI-8936442 https://reactome.org/PathwayBrowser/#/R-DDI-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Dictyostelium discoideum 47823 R-DME-8936442 https://reactome.org/PathwayBrowser/#/R-DME-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Drosophila melanogaster 47823 R-DRE-8936442 https://reactome.org/PathwayBrowser/#/R-DRE-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Danio rerio 47823 R-GGA-8936442 https://reactome.org/PathwayBrowser/#/R-GGA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Gallus gallus 47823 R-HSA-8936442 https://reactome.org/PathwayBrowser/#/R-HSA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds TAS Homo sapiens 47823 R-MMU-8936442 https://reactome.org/PathwayBrowser/#/R-MMU-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Mus musculus 47823 R-RNO-8936442 https://reactome.org/PathwayBrowser/#/R-RNO-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Rattus norvegicus 47823 R-SSC-8936442 https://reactome.org/PathwayBrowser/#/R-SSC-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Sus scrofa 47823 R-XTR-8936442 https://reactome.org/PathwayBrowser/#/R-XTR-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Xenopus tropicalis 47828 R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 47828 R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 47828 R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 47828 R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 47828 R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 47828 R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 47828 R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 4784 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 4784 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 4784 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 4784 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 4784 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 4784 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 4784 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 4784 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 4784 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 4784 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 4784 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 4784 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 4786 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 4786 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 4786 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 4786 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 4786 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 4786 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 4786 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 4786 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 4786 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 4786 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 4786 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 4786 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 4786 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 4786 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 4786 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 4786 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 4786 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 4786 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 4786 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 4786 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 4786 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 4786 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 4786 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 4786 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 4786 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 4786 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 4786 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 4786 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 4786 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 4786 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 4786 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 4786 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 4786 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 47923 R-BTA-427998 https://reactome.org/PathwayBrowser/#/R-BTA-427998 Proton-coupled di- and tri-peptide cotransport IEA Bos taurus 47923 R-CEL-427998 https://reactome.org/PathwayBrowser/#/R-CEL-427998 Proton-coupled di- and tri-peptide cotransport IEA Caenorhabditis elegans 47923 R-CFA-427998 https://reactome.org/PathwayBrowser/#/R-CFA-427998 Proton-coupled di- and tri-peptide cotransport IEA Canis familiaris 47923 R-DDI-427998 https://reactome.org/PathwayBrowser/#/R-DDI-427998 Proton-coupled di- and tri-peptide cotransport IEA Dictyostelium discoideum 47923 R-DME-427998 https://reactome.org/PathwayBrowser/#/R-DME-427998 Proton-coupled di- and tri-peptide cotransport IEA Drosophila melanogaster 47923 R-DRE-427998 https://reactome.org/PathwayBrowser/#/R-DRE-427998 Proton-coupled di- and tri-peptide cotransport IEA Danio rerio 47923 R-GGA-427998 https://reactome.org/PathwayBrowser/#/R-GGA-427998 Proton-coupled di- and tri-peptide cotransport IEA Gallus gallus 47923 R-HSA-427998 https://reactome.org/PathwayBrowser/#/R-HSA-427998 Proton-coupled di- and tri-peptide cotransport TAS Homo sapiens 47923 R-MMU-427998 https://reactome.org/PathwayBrowser/#/R-MMU-427998 Proton-coupled di- and tri-peptide cotransport IEA Mus musculus 47923 R-RNO-427998 https://reactome.org/PathwayBrowser/#/R-RNO-427998 Proton-coupled di- and tri-peptide cotransport IEA Rattus norvegicus 47923 R-SSC-427998 https://reactome.org/PathwayBrowser/#/R-SSC-427998 Proton-coupled di- and tri-peptide cotransport IEA Sus scrofa 47923 R-XTR-427998 https://reactome.org/PathwayBrowser/#/R-XTR-427998 Proton-coupled di- and tri-peptide cotransport IEA Xenopus tropicalis 47977 R-CEL-6786652 https://reactome.org/PathwayBrowser/#/R-CEL-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Caenorhabditis elegans 47977 R-DME-6786652 https://reactome.org/PathwayBrowser/#/R-DME-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Drosophila melanogaster 47977 R-DRE-6786652 https://reactome.org/PathwayBrowser/#/R-DRE-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Danio rerio 47977 R-HSA-6786652 https://reactome.org/PathwayBrowser/#/R-HSA-6786652 CHIT1 hydrolyses CHIT to 3xADGP TAS Homo sapiens 47977 R-MMU-6786652 https://reactome.org/PathwayBrowser/#/R-MMU-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Mus musculus 47977 R-PFA-6786652 https://reactome.org/PathwayBrowser/#/R-PFA-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Plasmodium falciparum 47977 R-RNO-6786652 https://reactome.org/PathwayBrowser/#/R-RNO-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Rattus norvegicus 47977 R-SCE-6786652 https://reactome.org/PathwayBrowser/#/R-SCE-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Saccharomyces cerevisiae 47977 R-SSC-6786652 https://reactome.org/PathwayBrowser/#/R-SSC-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Sus scrofa 47983 R-BTA-6810474 https://reactome.org/PathwayBrowser/#/R-BTA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Bos taurus 47983 R-CEL-6810474 https://reactome.org/PathwayBrowser/#/R-CEL-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Caenorhabditis elegans 47983 R-CFA-6810474 https://reactome.org/PathwayBrowser/#/R-CFA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Canis familiaris 47983 R-DDI-6810474 https://reactome.org/PathwayBrowser/#/R-DDI-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Dictyostelium discoideum 47983 R-DME-6810474 https://reactome.org/PathwayBrowser/#/R-DME-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Drosophila melanogaster 47983 R-DRE-6810474 https://reactome.org/PathwayBrowser/#/R-DRE-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Danio rerio 47983 R-GGA-6810474 https://reactome.org/PathwayBrowser/#/R-GGA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Gallus gallus 47983 R-HSA-6810474 https://reactome.org/PathwayBrowser/#/R-HSA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT TAS Homo sapiens 47983 R-MMU-6810474 https://reactome.org/PathwayBrowser/#/R-MMU-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Mus musculus 47983 R-RNO-6810474 https://reactome.org/PathwayBrowser/#/R-RNO-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Rattus norvegicus 47983 R-SSC-6810474 https://reactome.org/PathwayBrowser/#/R-SSC-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Sus scrofa 47983 R-XTR-6810474 https://reactome.org/PathwayBrowser/#/R-XTR-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Xenopus tropicalis 48095 R-BTA-5652195 https://reactome.org/PathwayBrowser/#/R-BTA-5652195 SORD oxidizes D-sorbitol to Fru IEA Bos taurus 48095 R-CEL-5652195 https://reactome.org/PathwayBrowser/#/R-CEL-5652195 SORD oxidizes D-sorbitol to Fru IEA Caenorhabditis elegans 48095 R-CFA-5652195 https://reactome.org/PathwayBrowser/#/R-CFA-5652195 SORD oxidizes D-sorbitol to Fru IEA Canis familiaris 48095 R-DME-5652195 https://reactome.org/PathwayBrowser/#/R-DME-5652195 SORD oxidizes D-sorbitol to Fru IEA Drosophila melanogaster 48095 R-GGA-5652195 https://reactome.org/PathwayBrowser/#/R-GGA-5652195 SORD oxidizes D-sorbitol to Fru IEA Gallus gallus 48095 R-HSA-5652195 https://reactome.org/PathwayBrowser/#/R-HSA-5652195 SORD oxidizes D-sorbitol to Fru TAS Homo sapiens 48095 R-MMU-5652195 https://reactome.org/PathwayBrowser/#/R-MMU-5652195 SORD oxidizes D-sorbitol to Fru IEA Mus musculus 48095 R-RNO-5652195 https://reactome.org/PathwayBrowser/#/R-RNO-5652195 SORD oxidizes D-sorbitol to Fru IEA Rattus norvegicus 48095 R-SCE-5652195 https://reactome.org/PathwayBrowser/#/R-SCE-5652195 SORD oxidizes D-sorbitol to Fru IEA Saccharomyces cerevisiae 48095 R-SPO-5652195 https://reactome.org/PathwayBrowser/#/R-SPO-5652195 SORD oxidizes D-sorbitol to Fru IEA Schizosaccharomyces pombe 48095 R-SSC-5652195 https://reactome.org/PathwayBrowser/#/R-SSC-5652195 SORD oxidizes D-sorbitol to Fru IEA Sus scrofa 48095 R-XTR-5652195 https://reactome.org/PathwayBrowser/#/R-XTR-5652195 SORD oxidizes D-sorbitol to Fru IEA Xenopus tropicalis 4814 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(34-41) binds to AGTR1 IEA Bos taurus 4814 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGRT1 IEA Bos taurus 4814 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(34-41) binds to AGTR1 IEA Caenorhabditis elegans 4814 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGRT1 IEA Caenorhabditis elegans 4814 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(34-41) binds to AGTR1 IEA Canis familiaris 4814 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGRT1 IEA Canis familiaris 4814 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(34-41) binds to AGTR1 IEA Drosophila melanogaster 4814 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGRT1 IEA Drosophila melanogaster 4814 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(34-41) binds to AGTR1 IEA Danio rerio 4814 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGRT1 IEA Danio rerio 4814 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(34-41) binds to AGTR1 IEA Gallus gallus 4814 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGRT1 IEA Gallus gallus 4814 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(34-41) binds to AGTR1 TAS Homo sapiens 4814 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGRT1 TAS Homo sapiens 4814 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(34-41) binds to AGTR1 IEA Mus musculus 4814 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGRT1 IEA Mus musculus 4814 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(34-41) binds to AGTR1 IEA Rattus norvegicus 4814 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGRT1 IEA Rattus norvegicus 4814 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(34-41) binds to AGTR1 IEA Sus scrofa 4814 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGRT1 IEA Sus scrofa 4828 R-BTA-549241 https://reactome.org/PathwayBrowser/#/R-BTA-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Bos taurus 4828 R-CEL-549241 https://reactome.org/PathwayBrowser/#/R-CEL-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 4828 R-DME-549241 https://reactome.org/PathwayBrowser/#/R-DME-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 4828 R-DRE-549241 https://reactome.org/PathwayBrowser/#/R-DRE-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Danio rerio 4828 R-GGA-549241 https://reactome.org/PathwayBrowser/#/R-GGA-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Gallus gallus 4828 R-HSA-549241 https://reactome.org/PathwayBrowser/#/R-HSA-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol TAS Homo sapiens 4828 R-MMU-549241 https://reactome.org/PathwayBrowser/#/R-MMU-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Mus musculus 4828 R-RNO-549241 https://reactome.org/PathwayBrowser/#/R-RNO-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Rattus norvegicus 4828 R-SSC-549241 https://reactome.org/PathwayBrowser/#/R-SSC-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Sus scrofa 4828 R-XTR-549241 https://reactome.org/PathwayBrowser/#/R-XTR-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 48408 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 48408 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 48408 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 48408 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 48408 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 48408 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 48408 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 48408 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 48408 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 48416 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(34-41) binds to AGTR1 IEA Bos taurus 48416 R-BTA-6786190 https://reactome.org/PathwayBrowser/#/R-BTA-6786190 CMBL hydrolyses OM to OLMS IEA Bos taurus 48416 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGRT1 IEA Bos taurus 48416 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(34-41) binds to AGTR1 IEA Caenorhabditis elegans 48416 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGRT1 IEA Caenorhabditis elegans 48416 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(34-41) binds to AGTR1 IEA Canis familiaris 48416 R-CFA-6786190 https://reactome.org/PathwayBrowser/#/R-CFA-6786190 CMBL hydrolyses OM to OLMS IEA Canis familiaris 48416 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGRT1 IEA Canis familiaris 48416 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(34-41) binds to AGTR1 IEA Drosophila melanogaster 48416 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGRT1 IEA Drosophila melanogaster 48416 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(34-41) binds to AGTR1 IEA Danio rerio 48416 R-DRE-6786190 https://reactome.org/PathwayBrowser/#/R-DRE-6786190 CMBL hydrolyses OM to OLMS IEA Danio rerio 48416 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGRT1 IEA Danio rerio 48416 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(34-41) binds to AGTR1 IEA Gallus gallus 48416 R-GGA-6786190 https://reactome.org/PathwayBrowser/#/R-GGA-6786190 CMBL hydrolyses OM to OLMS IEA Gallus gallus 48416 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGRT1 IEA Gallus gallus 48416 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(34-41) binds to AGTR1 TAS Homo sapiens 48416 R-HSA-6786190 https://reactome.org/PathwayBrowser/#/R-HSA-6786190 CMBL hydrolyses OM to OLMS TAS Homo sapiens 48416 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGRT1 TAS Homo sapiens 48416 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(34-41) binds to AGTR1 IEA Mus musculus 48416 R-MMU-6786190 https://reactome.org/PathwayBrowser/#/R-MMU-6786190 CMBL hydrolyses OM to OLMS IEA Mus musculus 48416 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGRT1 IEA Mus musculus 48416 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(34-41) binds to AGTR1 IEA Rattus norvegicus 48416 R-RNO-6786190 https://reactome.org/PathwayBrowser/#/R-RNO-6786190 CMBL hydrolyses OM to OLMS IEA Rattus norvegicus 48416 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGRT1 IEA Rattus norvegicus 48416 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(34-41) binds to AGTR1 IEA Sus scrofa 48416 R-SSC-6786190 https://reactome.org/PathwayBrowser/#/R-SSC-6786190 CMBL hydrolyses OM to OLMS IEA Sus scrofa 48416 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGRT1 IEA Sus scrofa 48416 R-XTR-6786190 https://reactome.org/PathwayBrowser/#/R-XTR-6786190 CMBL hydrolyses OM to OLMS IEA Xenopus tropicalis 4856 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 4856 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 4856 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 4856 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 4856 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 4856 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 4856 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 4856 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 4856 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 4856 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 4856 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 4856 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 4856 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 4856 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 4856 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 4856 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 4856 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 4856 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 4856 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 4856 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 4856 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 4856 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 4856 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 4856 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 4856 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 4856 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 4856 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 4856 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 4856 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 4856 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 4856 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 4856 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 4856 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 4856 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 4856 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 4856 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 4856 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 48621 R-HSA-2408507 https://reactome.org/PathwayBrowser/#/R-HSA-2408507 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK IEA Homo sapiens 48621 R-HSA-2408555 https://reactome.org/PathwayBrowser/#/R-HSA-2408555 Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer TAS Homo sapiens 48621 R-MMU-2408505 https://reactome.org/PathwayBrowser/#/R-MMU-2408505 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by Pstk TAS Mus musculus 4866 R-BTA-176521 https://reactome.org/PathwayBrowser/#/R-BTA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Bos taurus 4866 R-CFA-176521 https://reactome.org/PathwayBrowser/#/R-CFA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Canis familiaris 4866 R-DME-176521 https://reactome.org/PathwayBrowser/#/R-DME-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Drosophila melanogaster 4866 R-DRE-176521 https://reactome.org/PathwayBrowser/#/R-DRE-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Danio rerio 4866 R-GGA-176521 https://reactome.org/PathwayBrowser/#/R-GGA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Gallus gallus 4866 R-HSA-176521 https://reactome.org/PathwayBrowser/#/R-HSA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP TAS Homo sapiens 4866 R-MMU-176521 https://reactome.org/PathwayBrowser/#/R-MMU-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Mus musculus 4866 R-RNO-176521 https://reactome.org/PathwayBrowser/#/R-RNO-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Rattus norvegicus 4866 R-SSC-176521 https://reactome.org/PathwayBrowser/#/R-SSC-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Sus scrofa 4866 R-XTR-176521 https://reactome.org/PathwayBrowser/#/R-XTR-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Xenopus tropicalis 48736 R-BTA-193711 https://reactome.org/PathwayBrowser/#/R-BTA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 48736 R-BTA-193737 https://reactome.org/PathwayBrowser/#/R-BTA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Bos taurus 48736 R-BTA-193743 https://reactome.org/PathwayBrowser/#/R-BTA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 48736 R-CEL-193711 https://reactome.org/PathwayBrowser/#/R-CEL-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 48736 R-CEL-193743 https://reactome.org/PathwayBrowser/#/R-CEL-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 48736 R-CFA-193711 https://reactome.org/PathwayBrowser/#/R-CFA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 48736 R-CFA-193737 https://reactome.org/PathwayBrowser/#/R-CFA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Canis familiaris 48736 R-CFA-193743 https://reactome.org/PathwayBrowser/#/R-CFA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 48736 R-DME-193711 https://reactome.org/PathwayBrowser/#/R-DME-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 48736 R-DME-193743 https://reactome.org/PathwayBrowser/#/R-DME-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 48736 R-DRE-193711 https://reactome.org/PathwayBrowser/#/R-DRE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 48736 R-GGA-193711 https://reactome.org/PathwayBrowser/#/R-GGA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 48736 R-GGA-193743 https://reactome.org/PathwayBrowser/#/R-GGA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 48736 R-HSA-193711 https://reactome.org/PathwayBrowser/#/R-HSA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 48736 R-HSA-193737 https://reactome.org/PathwayBrowser/#/R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) TAS Homo sapiens 48736 R-HSA-193743 https://reactome.org/PathwayBrowser/#/R-HSA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 48736 R-HSA-193786 https://reactome.org/PathwayBrowser/#/R-HSA-193786 3,7,24THCA is translocated from the mitochondrial matrix to the cytosol TAS Homo sapiens 48736 R-MMU-193711 https://reactome.org/PathwayBrowser/#/R-MMU-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 48736 R-MMU-193737 https://reactome.org/PathwayBrowser/#/R-MMU-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Mus musculus 48736 R-MMU-193743 https://reactome.org/PathwayBrowser/#/R-MMU-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 48736 R-RNO-193711 https://reactome.org/PathwayBrowser/#/R-RNO-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 48736 R-RNO-193737 https://reactome.org/PathwayBrowser/#/R-RNO-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Rattus norvegicus 48736 R-RNO-193743 https://reactome.org/PathwayBrowser/#/R-RNO-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 48736 R-SCE-193711 https://reactome.org/PathwayBrowser/#/R-SCE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 48736 R-SCE-193743 https://reactome.org/PathwayBrowser/#/R-SCE-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 48736 R-SSC-193711 https://reactome.org/PathwayBrowser/#/R-SSC-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 48736 R-SSC-193737 https://reactome.org/PathwayBrowser/#/R-SSC-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Sus scrofa 48736 R-SSC-193743 https://reactome.org/PathwayBrowser/#/R-SSC-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 48736 R-XTR-193711 https://reactome.org/PathwayBrowser/#/R-XTR-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 48736 R-XTR-193743 https://reactome.org/PathwayBrowser/#/R-XTR-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 48765 R-BTA-6800149 https://reactome.org/PathwayBrowser/#/R-BTA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Bos taurus 48765 R-CEL-6800149 https://reactome.org/PathwayBrowser/#/R-CEL-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Caenorhabditis elegans 48765 R-CFA-6800149 https://reactome.org/PathwayBrowser/#/R-CFA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Canis familiaris 48765 R-DDI-6800149 https://reactome.org/PathwayBrowser/#/R-DDI-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Dictyostelium discoideum 48765 R-DME-6800149 https://reactome.org/PathwayBrowser/#/R-DME-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Drosophila melanogaster 48765 R-DRE-6800149 https://reactome.org/PathwayBrowser/#/R-DRE-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Danio rerio 48765 R-HSA-6800149 https://reactome.org/PathwayBrowser/#/R-HSA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII TAS Homo sapiens 48765 R-MMU-6800149 https://reactome.org/PathwayBrowser/#/R-MMU-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Mus musculus 48765 R-PFA-6800149 https://reactome.org/PathwayBrowser/#/R-PFA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Plasmodium falciparum 48765 R-SCE-6800149 https://reactome.org/PathwayBrowser/#/R-SCE-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Saccharomyces cerevisiae 48765 R-SPO-6800149 https://reactome.org/PathwayBrowser/#/R-SPO-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Schizosaccharomyces pombe 48765 R-SSC-6800149 https://reactome.org/PathwayBrowser/#/R-SSC-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Sus scrofa 48765 R-XTR-6800149 https://reactome.org/PathwayBrowser/#/R-XTR-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Xenopus tropicalis 48775 R-BTA-5662608 https://reactome.org/PathwayBrowser/#/R-BTA-5662608 MT2A binds cadmium IEA Bos taurus 48775 R-BTA-5662620 https://reactome.org/PathwayBrowser/#/R-BTA-5662620 MT3 binds cadmium IEA Bos taurus 48775 R-CFA-5662608 https://reactome.org/PathwayBrowser/#/R-CFA-5662608 MT2A binds cadmium IEA Canis familiaris 48775 R-CFA-5662620 https://reactome.org/PathwayBrowser/#/R-CFA-5662620 MT3 binds cadmium IEA Canis familiaris 48775 R-DRE-5662608 https://reactome.org/PathwayBrowser/#/R-DRE-5662608 MT2A binds cadmium IEA Danio rerio 48775 R-DRE-5662620 https://reactome.org/PathwayBrowser/#/R-DRE-5662620 MT3 binds cadmium IEA Danio rerio 48775 R-GGA-5662608 https://reactome.org/PathwayBrowser/#/R-GGA-5662608 MT2A binds cadmium IEA Gallus gallus 48775 R-GGA-5662620 https://reactome.org/PathwayBrowser/#/R-GGA-5662620 MT3 binds cadmium IEA Gallus gallus 48775 R-HSA-5661219 https://reactome.org/PathwayBrowser/#/R-HSA-5661219 MT1A binds cadmium IEA Homo sapiens 48775 R-HSA-5662595 https://reactome.org/PathwayBrowser/#/R-HSA-5662595 MT1E binds cadmium IEA Homo sapiens 48775 R-HSA-5662596 https://reactome.org/PathwayBrowser/#/R-HSA-5662596 MT1F binds cadmium IEA Homo sapiens 48775 R-HSA-5662597 https://reactome.org/PathwayBrowser/#/R-HSA-5662597 MT1H binds cadmium IEA Homo sapiens 48775 R-HSA-5662599 https://reactome.org/PathwayBrowser/#/R-HSA-5662599 MT1M binds cadmium IEA Homo sapiens 48775 R-HSA-5662608 https://reactome.org/PathwayBrowser/#/R-HSA-5662608 MT2A binds cadmium TAS Homo sapiens 48775 R-HSA-5662610 https://reactome.org/PathwayBrowser/#/R-HSA-5662610 MT1B binds cadmium IEA Homo sapiens 48775 R-HSA-5662617 https://reactome.org/PathwayBrowser/#/R-HSA-5662617 MT1G binds cadmium IEA Homo sapiens 48775 R-HSA-5662620 https://reactome.org/PathwayBrowser/#/R-HSA-5662620 MT3 binds cadmium TAS Homo sapiens 48775 R-HSA-5662622 https://reactome.org/PathwayBrowser/#/R-HSA-5662622 MT1X binds cadmium IEA Homo sapiens 48775 R-HSA-5662649 https://reactome.org/PathwayBrowser/#/R-HSA-5662649 MT4 binds cadmium IEA Homo sapiens 48775 R-MMU-5662608 https://reactome.org/PathwayBrowser/#/R-MMU-5662608 MT2A binds cadmium IEA Mus musculus 48775 R-MMU-5662620 https://reactome.org/PathwayBrowser/#/R-MMU-5662620 MT3 binds cadmium IEA Mus musculus 48775 R-MMU-5662651 https://reactome.org/PathwayBrowser/#/R-MMU-5662651 Mt4 binds cadmium TAS Mus musculus 48775 R-MMU-6798570 https://reactome.org/PathwayBrowser/#/R-MMU-6798570 Mt1 binds cadmium TAS Mus musculus 48775 R-RNO-5662608 https://reactome.org/PathwayBrowser/#/R-RNO-5662608 MT2A binds cadmium IEA Rattus norvegicus 48775 R-RNO-5662620 https://reactome.org/PathwayBrowser/#/R-RNO-5662620 MT3 binds cadmium IEA Rattus norvegicus 48775 R-SSC-5662608 https://reactome.org/PathwayBrowser/#/R-SSC-5662608 MT2A binds cadmium IEA Sus scrofa 48775 R-SSC-5662620 https://reactome.org/PathwayBrowser/#/R-SSC-5662620 MT3 binds cadmium IEA Sus scrofa 48778 R-BTA-193824 https://reactome.org/PathwayBrowser/#/R-BTA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Bos taurus 48778 R-BTA-193841 https://reactome.org/PathwayBrowser/#/R-BTA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Bos taurus 48778 R-CEL-193824 https://reactome.org/PathwayBrowser/#/R-CEL-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Caenorhabditis elegans 48778 R-CEL-193841 https://reactome.org/PathwayBrowser/#/R-CEL-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Caenorhabditis elegans 48778 R-CFA-193824 https://reactome.org/PathwayBrowser/#/R-CFA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Canis familiaris 48778 R-DDI-193824 https://reactome.org/PathwayBrowser/#/R-DDI-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Dictyostelium discoideum 48778 R-DDI-193841 https://reactome.org/PathwayBrowser/#/R-DDI-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Dictyostelium discoideum 48778 R-DME-193824 https://reactome.org/PathwayBrowser/#/R-DME-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Drosophila melanogaster 48778 R-DME-193841 https://reactome.org/PathwayBrowser/#/R-DME-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Drosophila melanogaster 48778 R-GGA-193824 https://reactome.org/PathwayBrowser/#/R-GGA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Gallus gallus 48778 R-HSA-193824 https://reactome.org/PathwayBrowser/#/R-HSA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one TAS Homo sapiens 48778 R-HSA-193841 https://reactome.org/PathwayBrowser/#/R-HSA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol TAS Homo sapiens 48778 R-MMU-193824 https://reactome.org/PathwayBrowser/#/R-MMU-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Mus musculus 48778 R-MMU-193841 https://reactome.org/PathwayBrowser/#/R-MMU-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Mus musculus 48778 R-RNO-193824 https://reactome.org/PathwayBrowser/#/R-RNO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Rattus norvegicus 48778 R-RNO-193841 https://reactome.org/PathwayBrowser/#/R-RNO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Rattus norvegicus 48778 R-SCE-193824 https://reactome.org/PathwayBrowser/#/R-SCE-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Saccharomyces cerevisiae 48778 R-SCE-193841 https://reactome.org/PathwayBrowser/#/R-SCE-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Saccharomyces cerevisiae 48778 R-SPO-193824 https://reactome.org/PathwayBrowser/#/R-SPO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Schizosaccharomyces pombe 48778 R-SPO-193841 https://reactome.org/PathwayBrowser/#/R-SPO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Schizosaccharomyces pombe 48778 R-SSC-193824 https://reactome.org/PathwayBrowser/#/R-SSC-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Sus scrofa 48778 R-SSC-193841 https://reactome.org/PathwayBrowser/#/R-SSC-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Sus scrofa 48778 R-XTR-193824 https://reactome.org/PathwayBrowser/#/R-XTR-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Xenopus tropicalis 48778 R-XTR-193841 https://reactome.org/PathwayBrowser/#/R-XTR-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Xenopus tropicalis 48825 R-BTA-193816 https://reactome.org/PathwayBrowser/#/R-BTA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Bos taurus 48825 R-BTA-193824 https://reactome.org/PathwayBrowser/#/R-BTA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Bos taurus 48825 R-CEL-193824 https://reactome.org/PathwayBrowser/#/R-CEL-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Caenorhabditis elegans 48825 R-CFA-193816 https://reactome.org/PathwayBrowser/#/R-CFA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Canis familiaris 48825 R-CFA-193824 https://reactome.org/PathwayBrowser/#/R-CFA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Canis familiaris 48825 R-CFA-193845 https://reactome.org/PathwayBrowser/#/R-CFA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Canis familiaris 48825 R-DDI-193824 https://reactome.org/PathwayBrowser/#/R-DDI-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Dictyostelium discoideum 48825 R-DME-193824 https://reactome.org/PathwayBrowser/#/R-DME-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Drosophila melanogaster 48825 R-DRE-193816 https://reactome.org/PathwayBrowser/#/R-DRE-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Danio rerio 48825 R-DRE-193845 https://reactome.org/PathwayBrowser/#/R-DRE-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Danio rerio 48825 R-GGA-193824 https://reactome.org/PathwayBrowser/#/R-GGA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Gallus gallus 48825 R-HSA-193816 https://reactome.org/PathwayBrowser/#/R-HSA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one TAS Homo sapiens 48825 R-HSA-193824 https://reactome.org/PathwayBrowser/#/R-HSA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one TAS Homo sapiens 48825 R-HSA-193845 https://reactome.org/PathwayBrowser/#/R-HSA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE TAS Homo sapiens 48825 R-MMU-193816 https://reactome.org/PathwayBrowser/#/R-MMU-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Mus musculus 48825 R-MMU-193824 https://reactome.org/PathwayBrowser/#/R-MMU-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Mus musculus 48825 R-MMU-193845 https://reactome.org/PathwayBrowser/#/R-MMU-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Mus musculus 48825 R-RNO-193816 https://reactome.org/PathwayBrowser/#/R-RNO-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Rattus norvegicus 48825 R-RNO-193824 https://reactome.org/PathwayBrowser/#/R-RNO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Rattus norvegicus 48825 R-RNO-193845 https://reactome.org/PathwayBrowser/#/R-RNO-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Rattus norvegicus 48825 R-SCE-193824 https://reactome.org/PathwayBrowser/#/R-SCE-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Saccharomyces cerevisiae 48825 R-SPO-193824 https://reactome.org/PathwayBrowser/#/R-SPO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Schizosaccharomyces pombe 48825 R-SSC-193816 https://reactome.org/PathwayBrowser/#/R-SSC-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Sus scrofa 48825 R-SSC-193824 https://reactome.org/PathwayBrowser/#/R-SSC-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Sus scrofa 48825 R-SSC-193845 https://reactome.org/PathwayBrowser/#/R-SSC-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Sus scrofa 48825 R-XTR-193816 https://reactome.org/PathwayBrowser/#/R-XTR-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Xenopus tropicalis 48825 R-XTR-193824 https://reactome.org/PathwayBrowser/#/R-XTR-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Xenopus tropicalis 48825 R-XTR-193845 https://reactome.org/PathwayBrowser/#/R-XTR-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Xenopus tropicalis 48833 R-BTA-193821 https://reactome.org/PathwayBrowser/#/R-BTA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Bos taurus 48833 R-CEL-193821 https://reactome.org/PathwayBrowser/#/R-CEL-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Caenorhabditis elegans 48833 R-CFA-193821 https://reactome.org/PathwayBrowser/#/R-CFA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Canis familiaris 48833 R-CFA-193845 https://reactome.org/PathwayBrowser/#/R-CFA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Canis familiaris 48833 R-DDI-193821 https://reactome.org/PathwayBrowser/#/R-DDI-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Dictyostelium discoideum 48833 R-DME-193821 https://reactome.org/PathwayBrowser/#/R-DME-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Drosophila melanogaster 48833 R-DRE-193845 https://reactome.org/PathwayBrowser/#/R-DRE-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Danio rerio 48833 R-GGA-193821 https://reactome.org/PathwayBrowser/#/R-GGA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Gallus gallus 48833 R-HSA-193821 https://reactome.org/PathwayBrowser/#/R-HSA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one TAS Homo sapiens 48833 R-HSA-193845 https://reactome.org/PathwayBrowser/#/R-HSA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE TAS Homo sapiens 48833 R-MMU-193821 https://reactome.org/PathwayBrowser/#/R-MMU-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Mus musculus 48833 R-MMU-193845 https://reactome.org/PathwayBrowser/#/R-MMU-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Mus musculus 48833 R-RNO-193821 https://reactome.org/PathwayBrowser/#/R-RNO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Rattus norvegicus 48833 R-RNO-193845 https://reactome.org/PathwayBrowser/#/R-RNO-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Rattus norvegicus 48833 R-SCE-193821 https://reactome.org/PathwayBrowser/#/R-SCE-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Saccharomyces cerevisiae 48833 R-SPO-193821 https://reactome.org/PathwayBrowser/#/R-SPO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Schizosaccharomyces pombe 48833 R-SSC-193821 https://reactome.org/PathwayBrowser/#/R-SSC-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Sus scrofa 48833 R-SSC-193845 https://reactome.org/PathwayBrowser/#/R-SSC-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Sus scrofa 48833 R-XTR-193821 https://reactome.org/PathwayBrowser/#/R-XTR-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Xenopus tropicalis 48833 R-XTR-193845 https://reactome.org/PathwayBrowser/#/R-XTR-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Xenopus tropicalis 48834 R-BTA-193800 https://reactome.org/PathwayBrowser/#/R-BTA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Bos taurus 48834 R-BTA-193821 https://reactome.org/PathwayBrowser/#/R-BTA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Bos taurus 48834 R-CEL-193800 https://reactome.org/PathwayBrowser/#/R-CEL-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Caenorhabditis elegans 48834 R-CEL-193821 https://reactome.org/PathwayBrowser/#/R-CEL-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Caenorhabditis elegans 48834 R-CFA-193821 https://reactome.org/PathwayBrowser/#/R-CFA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Canis familiaris 48834 R-DDI-193800 https://reactome.org/PathwayBrowser/#/R-DDI-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Dictyostelium discoideum 48834 R-DDI-193821 https://reactome.org/PathwayBrowser/#/R-DDI-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Dictyostelium discoideum 48834 R-DME-193800 https://reactome.org/PathwayBrowser/#/R-DME-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Drosophila melanogaster 48834 R-DME-193821 https://reactome.org/PathwayBrowser/#/R-DME-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Drosophila melanogaster 48834 R-GGA-193821 https://reactome.org/PathwayBrowser/#/R-GGA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Gallus gallus 48834 R-HSA-193800 https://reactome.org/PathwayBrowser/#/R-HSA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol TAS Homo sapiens 48834 R-HSA-193821 https://reactome.org/PathwayBrowser/#/R-HSA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one TAS Homo sapiens 48834 R-MMU-193800 https://reactome.org/PathwayBrowser/#/R-MMU-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Mus musculus 48834 R-MMU-193821 https://reactome.org/PathwayBrowser/#/R-MMU-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Mus musculus 48834 R-RNO-193800 https://reactome.org/PathwayBrowser/#/R-RNO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Rattus norvegicus 48834 R-RNO-193821 https://reactome.org/PathwayBrowser/#/R-RNO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Rattus norvegicus 48834 R-SCE-193800 https://reactome.org/PathwayBrowser/#/R-SCE-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Saccharomyces cerevisiae 48834 R-SCE-193821 https://reactome.org/PathwayBrowser/#/R-SCE-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Saccharomyces cerevisiae 48834 R-SPO-193800 https://reactome.org/PathwayBrowser/#/R-SPO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Schizosaccharomyces pombe 48834 R-SPO-193821 https://reactome.org/PathwayBrowser/#/R-SPO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Schizosaccharomyces pombe 48834 R-SSC-193800 https://reactome.org/PathwayBrowser/#/R-SSC-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Sus scrofa 48834 R-SSC-193821 https://reactome.org/PathwayBrowser/#/R-SSC-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Sus scrofa 48834 R-XTR-193800 https://reactome.org/PathwayBrowser/#/R-XTR-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Xenopus tropicalis 48834 R-XTR-193821 https://reactome.org/PathwayBrowser/#/R-XTR-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Xenopus tropicalis 48854 R-MTU-936655 https://reactome.org/PathwayBrowser/#/R-MTU-936655 sulfite results from reduction of APS TAS Mycobacterium tuberculosis 48854 R-MTU-936703 https://reactome.org/PathwayBrowser/#/R-MTU-936703 sulfite is reduced to sulfide TAS Mycobacterium tuberculosis 48861 R-BTA-8870465 https://reactome.org/PathwayBrowser/#/R-BTA-8870465 RGGT binds the RAB-binding subunit IEA Bos taurus 48861 R-BTA-8870466 https://reactome.org/PathwayBrowser/#/R-BTA-8870466 RGGT:CHM binds RABs IEA Bos taurus 48861 R-BTA-8870469 https://reactome.org/PathwayBrowser/#/R-BTA-8870469 RGGT geranylgeranylates RAB proteins IEA Bos taurus 48861 R-CEL-8870465 https://reactome.org/PathwayBrowser/#/R-CEL-8870465 RGGT binds the RAB-binding subunit IEA Caenorhabditis elegans 48861 R-CEL-8870466 https://reactome.org/PathwayBrowser/#/R-CEL-8870466 RGGT:CHM binds RABs IEA Caenorhabditis elegans 48861 R-CEL-8870469 https://reactome.org/PathwayBrowser/#/R-CEL-8870469 RGGT geranylgeranylates RAB proteins IEA Caenorhabditis elegans 48861 R-CFA-8870465 https://reactome.org/PathwayBrowser/#/R-CFA-8870465 RGGT binds the RAB-binding subunit IEA Canis familiaris 48861 R-CFA-8870466 https://reactome.org/PathwayBrowser/#/R-CFA-8870466 RGGT:CHM binds RABs IEA Canis familiaris 48861 R-CFA-8870469 https://reactome.org/PathwayBrowser/#/R-CFA-8870469 RGGT geranylgeranylates RAB proteins IEA Canis familiaris 48861 R-DDI-8870465 https://reactome.org/PathwayBrowser/#/R-DDI-8870465 RGGT binds the RAB-binding subunit IEA Dictyostelium discoideum 48861 R-DDI-8870466 https://reactome.org/PathwayBrowser/#/R-DDI-8870466 RGGT:CHM binds RABs IEA Dictyostelium discoideum 48861 R-DDI-8870469 https://reactome.org/PathwayBrowser/#/R-DDI-8870469 RGGT geranylgeranylates RAB proteins IEA Dictyostelium discoideum 48861 R-DME-8870465 https://reactome.org/PathwayBrowser/#/R-DME-8870465 RGGT binds the RAB-binding subunit IEA Drosophila melanogaster 48861 R-DME-8870466 https://reactome.org/PathwayBrowser/#/R-DME-8870466 RGGT:CHM binds RABs IEA Drosophila melanogaster 48861 R-DME-8870469 https://reactome.org/PathwayBrowser/#/R-DME-8870469 RGGT geranylgeranylates RAB proteins IEA Drosophila melanogaster 48861 R-DRE-8870465 https://reactome.org/PathwayBrowser/#/R-DRE-8870465 RGGT binds the RAB-binding subunit IEA Danio rerio 48861 R-DRE-8870466 https://reactome.org/PathwayBrowser/#/R-DRE-8870466 RGGT:CHM binds RABs IEA Danio rerio 48861 R-DRE-8870469 https://reactome.org/PathwayBrowser/#/R-DRE-8870469 RGGT geranylgeranylates RAB proteins IEA Danio rerio 48861 R-HSA-8870465 https://reactome.org/PathwayBrowser/#/R-HSA-8870465 RGGT binds the RAB-binding subunit TAS Homo sapiens 48861 R-HSA-8870466 https://reactome.org/PathwayBrowser/#/R-HSA-8870466 RGGT:CHM binds RABs TAS Homo sapiens 48861 R-HSA-8870469 https://reactome.org/PathwayBrowser/#/R-HSA-8870469 RGGT geranylgeranylates RAB proteins TAS Homo sapiens 48861 R-MMU-8870465 https://reactome.org/PathwayBrowser/#/R-MMU-8870465 RGGT binds the RAB-binding subunit IEA Mus musculus 48861 R-MMU-8870466 https://reactome.org/PathwayBrowser/#/R-MMU-8870466 RGGT:CHM binds RABs IEA Mus musculus 48861 R-MMU-8870469 https://reactome.org/PathwayBrowser/#/R-MMU-8870469 RGGT geranylgeranylates RAB proteins IEA Mus musculus 48861 R-PFA-8870465 https://reactome.org/PathwayBrowser/#/R-PFA-8870465 RGGT binds the RAB-binding subunit IEA Plasmodium falciparum 48861 R-PFA-8870466 https://reactome.org/PathwayBrowser/#/R-PFA-8870466 RGGT:CHM binds RABs IEA Plasmodium falciparum 48861 R-PFA-8870469 https://reactome.org/PathwayBrowser/#/R-PFA-8870469 RGGT geranylgeranylates RAB proteins IEA Plasmodium falciparum 48861 R-RNO-8870465 https://reactome.org/PathwayBrowser/#/R-RNO-8870465 RGGT binds the RAB-binding subunit IEA Rattus norvegicus 48861 R-RNO-8870466 https://reactome.org/PathwayBrowser/#/R-RNO-8870466 RGGT:CHM binds RABs IEA Rattus norvegicus 48861 R-RNO-8870469 https://reactome.org/PathwayBrowser/#/R-RNO-8870469 RGGT geranylgeranylates RAB proteins IEA Rattus norvegicus 48861 R-SCE-8870465 https://reactome.org/PathwayBrowser/#/R-SCE-8870465 RGGT binds the RAB-binding subunit IEA Saccharomyces cerevisiae 48861 R-SCE-8870466 https://reactome.org/PathwayBrowser/#/R-SCE-8870466 RGGT:CHM binds RABs IEA Saccharomyces cerevisiae 48861 R-SCE-8870469 https://reactome.org/PathwayBrowser/#/R-SCE-8870469 RGGT geranylgeranylates RAB proteins IEA Saccharomyces cerevisiae 48861 R-SPO-8870465 https://reactome.org/PathwayBrowser/#/R-SPO-8870465 RGGT binds the RAB-binding subunit IEA Schizosaccharomyces pombe 48861 R-SPO-8870466 https://reactome.org/PathwayBrowser/#/R-SPO-8870466 RGGT:CHM binds RABs IEA Schizosaccharomyces pombe 48861 R-SPO-8870469 https://reactome.org/PathwayBrowser/#/R-SPO-8870469 RGGT geranylgeranylates RAB proteins IEA Schizosaccharomyces pombe 48923 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 48923 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 48923 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 48923 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 48923 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 48923 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 48923 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 48923 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 48923 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 48923 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 48923 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 48923 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 48923 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 48923 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 48923 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 48923 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 48923 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 48923 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 48923 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 48923 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 48923 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 48923 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 48923 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 48923 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 48923 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 48923 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 48923 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 48923 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 48923 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 48923 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 48923 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 48923 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 48923 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 48923 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 48923 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 48923 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 48923 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 48923 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 48923 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 48923 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 48923 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 48923 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 48926 R-BTA-5692237 https://reactome.org/PathwayBrowser/#/R-BTA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Bos taurus 48926 R-CEL-5692237 https://reactome.org/PathwayBrowser/#/R-CEL-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Caenorhabditis elegans 48926 R-CFA-5692237 https://reactome.org/PathwayBrowser/#/R-CFA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Canis familiaris 48926 R-DDI-5692237 https://reactome.org/PathwayBrowser/#/R-DDI-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Dictyostelium discoideum 48926 R-DME-5692237 https://reactome.org/PathwayBrowser/#/R-DME-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Drosophila melanogaster 48926 R-DRE-5692237 https://reactome.org/PathwayBrowser/#/R-DRE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Danio rerio 48926 R-GGA-5692237 https://reactome.org/PathwayBrowser/#/R-GGA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Gallus gallus 48926 R-HSA-5692237 https://reactome.org/PathwayBrowser/#/R-HSA-5692237 ADH5 oxidises S-HMGSH to S-FGSH TAS Homo sapiens 48926 R-MMU-5692237 https://reactome.org/PathwayBrowser/#/R-MMU-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Mus musculus 48926 R-RNO-5692237 https://reactome.org/PathwayBrowser/#/R-RNO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Rattus norvegicus 48926 R-SCE-5692237 https://reactome.org/PathwayBrowser/#/R-SCE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Saccharomyces cerevisiae 48926 R-SPO-5692237 https://reactome.org/PathwayBrowser/#/R-SPO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Schizosaccharomyces pombe 48926 R-SSC-5692237 https://reactome.org/PathwayBrowser/#/R-SSC-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Sus scrofa 48926 R-XTR-5692237 https://reactome.org/PathwayBrowser/#/R-XTR-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Xenopus tropicalis 48950 R-BTA-352029 https://reactome.org/PathwayBrowser/#/R-BTA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Bos taurus 48950 R-CFA-352029 https://reactome.org/PathwayBrowser/#/R-CFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Canis familiaris 48950 R-DRE-352029 https://reactome.org/PathwayBrowser/#/R-DRE-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Danio rerio 48950 R-GGA-352029 https://reactome.org/PathwayBrowser/#/R-GGA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Gallus gallus 48950 R-HSA-352029 https://reactome.org/PathwayBrowser/#/R-HSA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine TAS Homo sapiens 48950 R-MMU-352029 https://reactome.org/PathwayBrowser/#/R-MMU-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Mus musculus 48950 R-PFA-352029 https://reactome.org/PathwayBrowser/#/R-PFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Plasmodium falciparum 48950 R-RNO-352029 https://reactome.org/PathwayBrowser/#/R-RNO-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Rattus norvegicus 48950 R-SSC-352029 https://reactome.org/PathwayBrowser/#/R-SSC-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Sus scrofa 48950 R-XTR-352029 https://reactome.org/PathwayBrowser/#/R-XTR-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Xenopus tropicalis 49031 R-BTA-5676940 https://reactome.org/PathwayBrowser/#/R-BTA-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Bos taurus 49031 R-CFA-5676940 https://reactome.org/PathwayBrowser/#/R-CFA-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Canis familiaris 49031 R-GGA-5676940 https://reactome.org/PathwayBrowser/#/R-GGA-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Gallus gallus 49031 R-HSA-5676912 https://reactome.org/PathwayBrowser/#/R-HSA-5676912 Methionine is oxidised to methionine sulfoxide TAS Homo sapiens 49031 R-HSA-5676926 https://reactome.org/PathwayBrowser/#/R-HSA-5676926 Methionine sulfoxide is oxidised to methionine sulfone TAS Homo sapiens 49031 R-HSA-5676940 https://reactome.org/PathwayBrowser/#/R-HSA-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine TAS Homo sapiens 49031 R-MMU-5676940 https://reactome.org/PathwayBrowser/#/R-MMU-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Mus musculus 49031 R-RNO-5676940 https://reactome.org/PathwayBrowser/#/R-RNO-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Rattus norvegicus 49031 R-SSC-5676940 https://reactome.org/PathwayBrowser/#/R-SSC-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Sus scrofa 49032 R-BTA-5676917 https://reactome.org/PathwayBrowser/#/R-BTA-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Bos taurus 49032 R-CEL-5676917 https://reactome.org/PathwayBrowser/#/R-CEL-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Caenorhabditis elegans 49032 R-CFA-5676917 https://reactome.org/PathwayBrowser/#/R-CFA-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Canis familiaris 49032 R-DME-5676917 https://reactome.org/PathwayBrowser/#/R-DME-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Drosophila melanogaster 49032 R-DRE-5676917 https://reactome.org/PathwayBrowser/#/R-DRE-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Danio rerio 49032 R-GGA-5676917 https://reactome.org/PathwayBrowser/#/R-GGA-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Gallus gallus 49032 R-HSA-5676912 https://reactome.org/PathwayBrowser/#/R-HSA-5676912 Methionine is oxidised to methionine sulfoxide TAS Homo sapiens 49032 R-HSA-5676917 https://reactome.org/PathwayBrowser/#/R-HSA-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine TAS Homo sapiens 49032 R-HSA-5676926 https://reactome.org/PathwayBrowser/#/R-HSA-5676926 Methionine sulfoxide is oxidised to methionine sulfone TAS Homo sapiens 49032 R-MMU-5676917 https://reactome.org/PathwayBrowser/#/R-MMU-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Mus musculus 49032 R-RNO-5676917 https://reactome.org/PathwayBrowser/#/R-RNO-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Rattus norvegicus 49032 R-SSC-5676917 https://reactome.org/PathwayBrowser/#/R-SSC-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Sus scrofa 49108 R-BTA-5662660 https://reactome.org/PathwayBrowser/#/R-BTA-5662660 Dopachrome is transformed to DHICA by DCT IEA Bos taurus 49108 R-CEL-5662660 https://reactome.org/PathwayBrowser/#/R-CEL-5662660 Dopachrome is transformed to DHICA by DCT IEA Caenorhabditis elegans 49108 R-CFA-5662660 https://reactome.org/PathwayBrowser/#/R-CFA-5662660 Dopachrome is transformed to DHICA by DCT IEA Canis familiaris 49108 R-DDI-5662660 https://reactome.org/PathwayBrowser/#/R-DDI-5662660 Dopachrome is transformed to DHICA by DCT IEA Dictyostelium discoideum 49108 R-DRE-5662660 https://reactome.org/PathwayBrowser/#/R-DRE-5662660 Dopachrome is transformed to DHICA by DCT IEA Danio rerio 49108 R-GGA-5662660 https://reactome.org/PathwayBrowser/#/R-GGA-5662660 Dopachrome is transformed to DHICA by DCT IEA Gallus gallus 49108 R-HSA-5662660 https://reactome.org/PathwayBrowser/#/R-HSA-5662660 Dopachrome is transformed to DHICA by DCT TAS Homo sapiens 49108 R-HSA-5662706 https://reactome.org/PathwayBrowser/#/R-HSA-5662706 Dopachrome transforms to DHI TAS Homo sapiens 49108 R-HSA-5672019 https://reactome.org/PathwayBrowser/#/R-HSA-5672019 Leucodopachrome, L-Dopaquinone transform to Dopachrome, L-Dopa TAS Homo sapiens 49108 R-MMU-5662660 https://reactome.org/PathwayBrowser/#/R-MMU-5662660 Dopachrome is transformed to DHICA by DCT IEA Mus musculus 49108 R-RNO-5662660 https://reactome.org/PathwayBrowser/#/R-RNO-5662660 Dopachrome is transformed to DHICA by DCT IEA Rattus norvegicus 49108 R-SSC-5662660 https://reactome.org/PathwayBrowser/#/R-SSC-5662660 Dopachrome is transformed to DHICA by DCT IEA Sus scrofa 49108 R-XTR-5662660 https://reactome.org/PathwayBrowser/#/R-XTR-5662660 Dopachrome is transformed to DHICA by DCT IEA Xenopus tropicalis 4917 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 4917 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 4917 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 4917 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 4917 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 4917 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 4917 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 4917 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 4917 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 4918 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 4918 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 4918 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 4918 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 4918 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 4918 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 4918 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 4918 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 4918 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 49189 R-BTA-389609 https://reactome.org/PathwayBrowser/#/R-BTA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Bos taurus 49189 R-BTA-389611 https://reactome.org/PathwayBrowser/#/R-BTA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Bos taurus 49189 R-CEL-389609 https://reactome.org/PathwayBrowser/#/R-CEL-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Caenorhabditis elegans 49189 R-CEL-389611 https://reactome.org/PathwayBrowser/#/R-CEL-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Caenorhabditis elegans 49189 R-CFA-389609 https://reactome.org/PathwayBrowser/#/R-CFA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Canis familiaris 49189 R-CFA-389611 https://reactome.org/PathwayBrowser/#/R-CFA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Canis familiaris 49189 R-DDI-389609 https://reactome.org/PathwayBrowser/#/R-DDI-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Dictyostelium discoideum 49189 R-DDI-389611 https://reactome.org/PathwayBrowser/#/R-DDI-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Dictyostelium discoideum 49189 R-DME-389609 https://reactome.org/PathwayBrowser/#/R-DME-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Drosophila melanogaster 49189 R-DME-389611 https://reactome.org/PathwayBrowser/#/R-DME-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Drosophila melanogaster 49189 R-DRE-389609 https://reactome.org/PathwayBrowser/#/R-DRE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Danio rerio 49189 R-DRE-389611 https://reactome.org/PathwayBrowser/#/R-DRE-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Danio rerio 49189 R-GGA-389609 https://reactome.org/PathwayBrowser/#/R-GGA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Gallus gallus 49189 R-GGA-389611 https://reactome.org/PathwayBrowser/#/R-GGA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Gallus gallus 49189 R-HSA-389609 https://reactome.org/PathwayBrowser/#/R-HSA-389609 ALDH3A2-2 oxidizes pristanal to pristanate TAS Homo sapiens 49189 R-HSA-389611 https://reactome.org/PathwayBrowser/#/R-HSA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA TAS Homo sapiens 49189 R-MMU-389609 https://reactome.org/PathwayBrowser/#/R-MMU-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Mus musculus 49189 R-MMU-389611 https://reactome.org/PathwayBrowser/#/R-MMU-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Mus musculus 49189 R-RNO-389609 https://reactome.org/PathwayBrowser/#/R-RNO-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Rattus norvegicus 49189 R-RNO-389611 https://reactome.org/PathwayBrowser/#/R-RNO-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Rattus norvegicus 49189 R-SCE-389609 https://reactome.org/PathwayBrowser/#/R-SCE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Saccharomyces cerevisiae 49189 R-SCE-389611 https://reactome.org/PathwayBrowser/#/R-SCE-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Saccharomyces cerevisiae 49189 R-SPO-389611 https://reactome.org/PathwayBrowser/#/R-SPO-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Schizosaccharomyces pombe 49189 R-SSC-389609 https://reactome.org/PathwayBrowser/#/R-SSC-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Sus scrofa 49189 R-SSC-389611 https://reactome.org/PathwayBrowser/#/R-SSC-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Sus scrofa 49189 R-XTR-389611 https://reactome.org/PathwayBrowser/#/R-XTR-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Xenopus tropicalis 49537 R-BTA-2396009 https://reactome.org/PathwayBrowser/#/R-BTA-2396009 STING binds c-di-GMP IEA Bos taurus 49537 R-BTA-9013869 https://reactome.org/PathwayBrowser/#/R-BTA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Bos taurus 49537 R-CEL-9013869 https://reactome.org/PathwayBrowser/#/R-CEL-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Caenorhabditis elegans 49537 R-CFA-9013869 https://reactome.org/PathwayBrowser/#/R-CFA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Canis familiaris 49537 R-DDI-9013869 https://reactome.org/PathwayBrowser/#/R-DDI-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Dictyostelium discoideum 49537 R-DME-2396009 https://reactome.org/PathwayBrowser/#/R-DME-2396009 STING binds c-di-GMP IEA Drosophila melanogaster 49537 R-DME-9013869 https://reactome.org/PathwayBrowser/#/R-DME-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Drosophila melanogaster 49537 R-DRE-2396009 https://reactome.org/PathwayBrowser/#/R-DRE-2396009 STING binds c-di-GMP IEA Danio rerio 49537 R-GGA-2396009 https://reactome.org/PathwayBrowser/#/R-GGA-2396009 STING binds c-di-GMP IEA Gallus gallus 49537 R-GGA-9013869 https://reactome.org/PathwayBrowser/#/R-GGA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Gallus gallus 49537 R-HSA-1834939 https://reactome.org/PathwayBrowser/#/R-HSA-1834939 STING recruits TBK1 and IRF3 TAS Homo sapiens 49537 R-HSA-2396009 https://reactome.org/PathwayBrowser/#/R-HSA-2396009 STING binds c-di-GMP TAS Homo sapiens 49537 R-HSA-9013869 https://reactome.org/PathwayBrowser/#/R-HSA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP TAS Homo sapiens 49537 R-MMU-2396009 https://reactome.org/PathwayBrowser/#/R-MMU-2396009 STING binds c-di-GMP IEA Mus musculus 49537 R-MMU-9013869 https://reactome.org/PathwayBrowser/#/R-MMU-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Mus musculus 49537 R-RNO-2396009 https://reactome.org/PathwayBrowser/#/R-RNO-2396009 STING binds c-di-GMP IEA Rattus norvegicus 49537 R-RNO-9013869 https://reactome.org/PathwayBrowser/#/R-RNO-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Rattus norvegicus 49537 R-SSC-2396009 https://reactome.org/PathwayBrowser/#/R-SSC-2396009 STING binds c-di-GMP IEA Sus scrofa 49537 R-SSC-9013869 https://reactome.org/PathwayBrowser/#/R-SSC-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Sus scrofa 49537 R-XTR-2396009 https://reactome.org/PathwayBrowser/#/R-XTR-2396009 STING binds c-di-GMP IEA Xenopus tropicalis 49537 R-XTR-9013869 https://reactome.org/PathwayBrowser/#/R-XTR-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Xenopus tropicalis 49552 R-BTA-3299753 https://reactome.org/PathwayBrowser/#/R-BTA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Bos taurus 49552 R-BTA-3697860 https://reactome.org/PathwayBrowser/#/R-BTA-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Bos taurus 49552 R-BTA-5662613 https://reactome.org/PathwayBrowser/#/R-BTA-5662613 MT3 exchanges zinc for copper IEA Bos taurus 49552 R-BTA-5662986 https://reactome.org/PathwayBrowser/#/R-BTA-5662986 MT2A binds copper IEA Bos taurus 49552 R-BTA-8951723 https://reactome.org/PathwayBrowser/#/R-BTA-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Bos taurus 49552 R-CEL-5336199 https://reactome.org/PathwayBrowser/#/R-CEL-5336199 cutc-1 binds Cu+ TAS Caenorhabditis elegans 49552 R-CFA-3299753 https://reactome.org/PathwayBrowser/#/R-CFA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Canis familiaris 49552 R-CFA-3697860 https://reactome.org/PathwayBrowser/#/R-CFA-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Canis familiaris 49552 R-CFA-5662613 https://reactome.org/PathwayBrowser/#/R-CFA-5662613 MT3 exchanges zinc for copper IEA Canis familiaris 49552 R-CFA-5662986 https://reactome.org/PathwayBrowser/#/R-CFA-5662986 MT2A binds copper IEA Canis familiaris 49552 R-CFA-6803545 https://reactome.org/PathwayBrowser/#/R-CFA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Canis familiaris 49552 R-CFA-8951723 https://reactome.org/PathwayBrowser/#/R-CFA-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Canis familiaris 49552 R-DDI-3299753 https://reactome.org/PathwayBrowser/#/R-DDI-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Dictyostelium discoideum 49552 R-DDI-3697860 https://reactome.org/PathwayBrowser/#/R-DDI-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Dictyostelium discoideum 49552 R-DDI-8951723 https://reactome.org/PathwayBrowser/#/R-DDI-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Dictyostelium discoideum 49552 R-DME-3299753 https://reactome.org/PathwayBrowser/#/R-DME-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Drosophila melanogaster 49552 R-DME-3697860 https://reactome.org/PathwayBrowser/#/R-DME-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Drosophila melanogaster 49552 R-DME-8951723 https://reactome.org/PathwayBrowser/#/R-DME-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Drosophila melanogaster 49552 R-DRE-5662613 https://reactome.org/PathwayBrowser/#/R-DRE-5662613 MT3 exchanges zinc for copper IEA Danio rerio 49552 R-DRE-5662986 https://reactome.org/PathwayBrowser/#/R-DRE-5662986 MT2A binds copper IEA Danio rerio 49552 R-DRE-6803545 https://reactome.org/PathwayBrowser/#/R-DRE-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Danio rerio 49552 R-GGA-3299753 https://reactome.org/PathwayBrowser/#/R-GGA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Gallus gallus 49552 R-GGA-3697860 https://reactome.org/PathwayBrowser/#/R-GGA-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Gallus gallus 49552 R-GGA-5662613 https://reactome.org/PathwayBrowser/#/R-GGA-5662613 MT3 exchanges zinc for copper IEA Gallus gallus 49552 R-GGA-5662986 https://reactome.org/PathwayBrowser/#/R-GGA-5662986 MT2A binds copper IEA Gallus gallus 49552 R-GGA-6803545 https://reactome.org/PathwayBrowser/#/R-GGA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Gallus gallus 49552 R-GGA-8951723 https://reactome.org/PathwayBrowser/#/R-GGA-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Gallus gallus 49552 R-HSA-3299753 https://reactome.org/PathwayBrowser/#/R-HSA-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 TAS Homo sapiens 49552 R-HSA-3697838 https://reactome.org/PathwayBrowser/#/R-HSA-3697838 ATP7A transfers Cu from ATOX1 to SOD3 IEA Homo sapiens 49552 R-HSA-3697860 https://reactome.org/PathwayBrowser/#/R-HSA-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ TAS Homo sapiens 49552 R-HSA-3780958 https://reactome.org/PathwayBrowser/#/R-HSA-3780958 SOD1:Zn2+ apoenzyme binds CCS:Cu1+ (mitochondrial) IEA Homo sapiens 49552 R-HSA-3780979 https://reactome.org/PathwayBrowser/#/R-HSA-3780979 CCS transfers Cu to SOD1 (mitochondrial) IEA Homo sapiens 49552 R-HSA-5334788 https://reactome.org/PathwayBrowser/#/R-HSA-5334788 CUTC binds Cu+ IEA Homo sapiens 49552 R-HSA-5662613 https://reactome.org/PathwayBrowser/#/R-HSA-5662613 MT3 exchanges zinc for copper TAS Homo sapiens 49552 R-HSA-5662647 https://reactome.org/PathwayBrowser/#/R-HSA-5662647 MT4 binds copper IEA Homo sapiens 49552 R-HSA-5662986 https://reactome.org/PathwayBrowser/#/R-HSA-5662986 MT2A binds copper TAS Homo sapiens 49552 R-HSA-5663002 https://reactome.org/PathwayBrowser/#/R-HSA-5663002 MT3 binds copper IEA Homo sapiens 49552 R-HSA-6803545 https://reactome.org/PathwayBrowser/#/R-HSA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen TAS Homo sapiens 49552 R-HSA-8951723 https://reactome.org/PathwayBrowser/#/R-HSA-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates TAS Homo sapiens 49552 R-MMU-3299753 https://reactome.org/PathwayBrowser/#/R-MMU-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Mus musculus 49552 R-MMU-3697860 https://reactome.org/PathwayBrowser/#/R-MMU-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Mus musculus 49552 R-MMU-3697899 https://reactome.org/PathwayBrowser/#/R-MMU-3697899 Atp7a transfers Cu from Atox1 to Sod3 TAS Mus musculus 49552 R-MMU-3780959 https://reactome.org/PathwayBrowser/#/R-MMU-3780959 Sod1 apoenzyme binds Ccs TAS Mus musculus 49552 R-MMU-3780963 https://reactome.org/PathwayBrowser/#/R-MMU-3780963 Ccs transfers Cu to Sod1 TAS Mus musculus 49552 R-MMU-5662613 https://reactome.org/PathwayBrowser/#/R-MMU-5662613 MT3 exchanges zinc for copper IEA Mus musculus 49552 R-MMU-5662986 https://reactome.org/PathwayBrowser/#/R-MMU-5662986 MT2A binds copper IEA Mus musculus 49552 R-MMU-5683438 https://reactome.org/PathwayBrowser/#/R-MMU-5683438 Mt4 binds copper TAS Mus musculus 49552 R-MMU-6798571 https://reactome.org/PathwayBrowser/#/R-MMU-6798571 Mt3 binds copper TAS Mus musculus 49552 R-MMU-6803545 https://reactome.org/PathwayBrowser/#/R-MMU-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Mus musculus 49552 R-MMU-8951723 https://reactome.org/PathwayBrowser/#/R-MMU-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Mus musculus 49552 R-RNO-3299753 https://reactome.org/PathwayBrowser/#/R-RNO-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Rattus norvegicus 49552 R-RNO-3697860 https://reactome.org/PathwayBrowser/#/R-RNO-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Rattus norvegicus 49552 R-RNO-5662613 https://reactome.org/PathwayBrowser/#/R-RNO-5662613 MT3 exchanges zinc for copper IEA Rattus norvegicus 49552 R-RNO-5662986 https://reactome.org/PathwayBrowser/#/R-RNO-5662986 MT2A binds copper IEA Rattus norvegicus 49552 R-RNO-6803545 https://reactome.org/PathwayBrowser/#/R-RNO-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Rattus norvegicus 49552 R-RNO-8951723 https://reactome.org/PathwayBrowser/#/R-RNO-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Rattus norvegicus 49552 R-SCE-3299753 https://reactome.org/PathwayBrowser/#/R-SCE-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Saccharomyces cerevisiae 49552 R-SCE-3697860 https://reactome.org/PathwayBrowser/#/R-SCE-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Saccharomyces cerevisiae 49552 R-SCE-8951723 https://reactome.org/PathwayBrowser/#/R-SCE-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Saccharomyces cerevisiae 49552 R-SSC-3299753 https://reactome.org/PathwayBrowser/#/R-SSC-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Sus scrofa 49552 R-SSC-3697860 https://reactome.org/PathwayBrowser/#/R-SSC-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Sus scrofa 49552 R-SSC-5662613 https://reactome.org/PathwayBrowser/#/R-SSC-5662613 MT3 exchanges zinc for copper IEA Sus scrofa 49552 R-SSC-5662986 https://reactome.org/PathwayBrowser/#/R-SSC-5662986 MT2A binds copper IEA Sus scrofa 49552 R-SSC-6803545 https://reactome.org/PathwayBrowser/#/R-SSC-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Sus scrofa 49552 R-SSC-8951723 https://reactome.org/PathwayBrowser/#/R-SSC-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Sus scrofa 49552 R-XTR-3299753 https://reactome.org/PathwayBrowser/#/R-XTR-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Xenopus tropicalis 49552 R-XTR-3697860 https://reactome.org/PathwayBrowser/#/R-XTR-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Xenopus tropicalis 49552 R-XTR-6803545 https://reactome.org/PathwayBrowser/#/R-XTR-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Xenopus tropicalis 49552 R-XTR-8951723 https://reactome.org/PathwayBrowser/#/R-XTR-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Xenopus tropicalis 49601 R-BTA-164651 https://reactome.org/PathwayBrowser/#/R-BTA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Bos taurus 49601 R-BTA-189465 https://reactome.org/PathwayBrowser/#/R-BTA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Bos taurus 49601 R-BTA-70994 https://reactome.org/PathwayBrowser/#/R-BTA-70994 SDH complex dehydrogenates succinate IEA Bos taurus 49601 R-BTA-9855252 https://reactome.org/PathwayBrowser/#/R-BTA-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Bos taurus 49601 R-CEL-164651 https://reactome.org/PathwayBrowser/#/R-CEL-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Caenorhabditis elegans 49601 R-CEL-189465 https://reactome.org/PathwayBrowser/#/R-CEL-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Caenorhabditis elegans 49601 R-CEL-70994 https://reactome.org/PathwayBrowser/#/R-CEL-70994 SDH complex dehydrogenates succinate IEA Caenorhabditis elegans 49601 R-CFA-189465 https://reactome.org/PathwayBrowser/#/R-CFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Canis familiaris 49601 R-CFA-70994 https://reactome.org/PathwayBrowser/#/R-CFA-70994 SDH complex dehydrogenates succinate IEA Canis familiaris 49601 R-DDI-164651 https://reactome.org/PathwayBrowser/#/R-DDI-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Dictyostelium discoideum 49601 R-DDI-189465 https://reactome.org/PathwayBrowser/#/R-DDI-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Dictyostelium discoideum 49601 R-DDI-70994 https://reactome.org/PathwayBrowser/#/R-DDI-70994 SDH complex dehydrogenates succinate IEA Dictyostelium discoideum 49601 R-DME-164651 https://reactome.org/PathwayBrowser/#/R-DME-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Drosophila melanogaster 49601 R-DME-189465 https://reactome.org/PathwayBrowser/#/R-DME-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Drosophila melanogaster 49601 R-DME-70994 https://reactome.org/PathwayBrowser/#/R-DME-70994 SDH complex dehydrogenates succinate IEA Drosophila melanogaster 49601 R-DRE-164651 https://reactome.org/PathwayBrowser/#/R-DRE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Danio rerio 49601 R-DRE-189465 https://reactome.org/PathwayBrowser/#/R-DRE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Danio rerio 49601 R-DRE-70994 https://reactome.org/PathwayBrowser/#/R-DRE-70994 SDH complex dehydrogenates succinate IEA Danio rerio 49601 R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus 49601 R-GGA-189465 https://reactome.org/PathwayBrowser/#/R-GGA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Gallus gallus 49601 R-GGA-421447 https://reactome.org/PathwayBrowser/#/R-GGA-421447 protoporphyrin IX + Fe++ => heme + 2 H+ TAS Gallus gallus 49601 R-GGA-70994 https://reactome.org/PathwayBrowser/#/R-GGA-70994 SDH complex dehydrogenates succinate IEA Gallus gallus 49601 R-HSA-163213 https://reactome.org/PathwayBrowser/#/R-HSA-163213 Transfer of electrons through the succinate dehydrogenase complex IEA Homo sapiens 49601 R-HSA-164651 https://reactome.org/PathwayBrowser/#/R-HSA-164651 Electron transfer from ubiquinol to cytochrome c of complex III TAS Homo sapiens 49601 R-HSA-189465 https://reactome.org/PathwayBrowser/#/R-HSA-189465 FECH binds Fe2+ to PRIN9 to form heme TAS Homo sapiens 49601 R-HSA-70994 https://reactome.org/PathwayBrowser/#/R-HSA-70994 SDH complex dehydrogenates succinate TAS Homo sapiens 49601 R-HSA-9855252 https://reactome.org/PathwayBrowser/#/R-HSA-9855252 SDHA:SDHB binds to SDHC:SDHD TAS Homo sapiens 49601 R-MMU-164651 https://reactome.org/PathwayBrowser/#/R-MMU-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Mus musculus 49601 R-MMU-189465 https://reactome.org/PathwayBrowser/#/R-MMU-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Mus musculus 49601 R-MMU-70994 https://reactome.org/PathwayBrowser/#/R-MMU-70994 SDH complex dehydrogenates succinate IEA Mus musculus 49601 R-MMU-9855252 https://reactome.org/PathwayBrowser/#/R-MMU-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Mus musculus 49601 R-PFA-189465 https://reactome.org/PathwayBrowser/#/R-PFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Plasmodium falciparum 49601 R-RNO-164651 https://reactome.org/PathwayBrowser/#/R-RNO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Rattus norvegicus 49601 R-RNO-189465 https://reactome.org/PathwayBrowser/#/R-RNO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Rattus norvegicus 49601 R-RNO-70994 https://reactome.org/PathwayBrowser/#/R-RNO-70994 SDH complex dehydrogenates succinate IEA Rattus norvegicus 49601 R-SCE-164651 https://reactome.org/PathwayBrowser/#/R-SCE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Saccharomyces cerevisiae 49601 R-SCE-189465 https://reactome.org/PathwayBrowser/#/R-SCE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Saccharomyces cerevisiae 49601 R-SCE-70994 https://reactome.org/PathwayBrowser/#/R-SCE-70994 SDH complex dehydrogenates succinate IEA Saccharomyces cerevisiae 49601 R-SPO-164651 https://reactome.org/PathwayBrowser/#/R-SPO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Schizosaccharomyces pombe 49601 R-SPO-189465 https://reactome.org/PathwayBrowser/#/R-SPO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Schizosaccharomyces pombe 49601 R-SPO-70994 https://reactome.org/PathwayBrowser/#/R-SPO-70994 SDH complex dehydrogenates succinate IEA Schizosaccharomyces pombe 49601 R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa 49601 R-SSC-189465 https://reactome.org/PathwayBrowser/#/R-SSC-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Sus scrofa 49601 R-SSC-70994 https://reactome.org/PathwayBrowser/#/R-SSC-70994 SDH complex dehydrogenates succinate IEA Sus scrofa 49601 R-SSC-9855252 https://reactome.org/PathwayBrowser/#/R-SSC-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Sus scrofa 49601 R-XTR-70994 https://reactome.org/PathwayBrowser/#/R-XTR-70994 SDH complex dehydrogenates succinate IEA Xenopus tropicalis 49601 R-XTR-9855252 https://reactome.org/PathwayBrowser/#/R-XTR-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Xenopus tropicalis 49603 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 49603 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 49603 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 49603 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 49603 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 49603 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 49603 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 49603 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 49603 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 49603 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 49603 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 49603 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 49603 R-HSA-1220610 https://reactome.org/PathwayBrowser/#/R-HSA-1220610 Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants TAS Homo sapiens 49603 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 49603 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 49603 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 49603 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 49603 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 49603 R-HSA-9665284 https://reactome.org/PathwayBrowser/#/R-HSA-9665284 Resistant ERBB2 KD mutants do not bind lapatinib TAS Homo sapiens 49603 R-HSA-9665389 https://reactome.org/PathwayBrowser/#/R-HSA-9665389 Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate TAS Homo sapiens 49603 R-HSA-9665412 https://reactome.org/PathwayBrowser/#/R-HSA-9665412 ERBB2 ECD mutants bind TKIs TAS Homo sapiens 49603 R-HSA-9665702 https://reactome.org/PathwayBrowser/#/R-HSA-9665702 ERBB2 TMD/JMD mutants bind TKIs TAS Homo sapiens 49603 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 49603 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 49603 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 49603 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 49603 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 49603 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 49668 R-HSA-1220610 https://reactome.org/PathwayBrowser/#/R-HSA-1220610 Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants TAS Homo sapiens 49668 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 49668 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 49713 R-BTA-425822 https://reactome.org/PathwayBrowser/#/R-BTA-425822 K+-independent Li+/Ca2+ exchanger transport IEA Bos taurus 49713 R-BTA-8953499 https://reactome.org/PathwayBrowser/#/R-BTA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Bos taurus 49713 R-CEL-425822 https://reactome.org/PathwayBrowser/#/R-CEL-425822 K+-independent Li+/Ca2+ exchanger transport IEA Caenorhabditis elegans 49713 R-CEL-8953499 https://reactome.org/PathwayBrowser/#/R-CEL-8953499 IMPAD1 hydrolyses PAP to AMP IEA Caenorhabditis elegans 49713 R-CFA-425822 https://reactome.org/PathwayBrowser/#/R-CFA-425822 K+-independent Li+/Ca2+ exchanger transport IEA Canis familiaris 49713 R-CFA-8953499 https://reactome.org/PathwayBrowser/#/R-CFA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Canis familiaris 49713 R-DDI-8953499 https://reactome.org/PathwayBrowser/#/R-DDI-8953499 IMPAD1 hydrolyses PAP to AMP IEA Dictyostelium discoideum 49713 R-DME-425822 https://reactome.org/PathwayBrowser/#/R-DME-425822 K+-independent Li+/Ca2+ exchanger transport IEA Drosophila melanogaster 49713 R-DME-8953499 https://reactome.org/PathwayBrowser/#/R-DME-8953499 IMPAD1 hydrolyses PAP to AMP IEA Drosophila melanogaster 49713 R-DRE-8953499 https://reactome.org/PathwayBrowser/#/R-DRE-8953499 IMPAD1 hydrolyses PAP to AMP IEA Danio rerio 49713 R-HSA-425822 https://reactome.org/PathwayBrowser/#/R-HSA-425822 K+-independent Li+/Ca2+ exchanger transport TAS Homo sapiens 49713 R-HSA-8953499 https://reactome.org/PathwayBrowser/#/R-HSA-8953499 IMPAD1 hydrolyses PAP to AMP TAS Homo sapiens 49713 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 49713 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 49713 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 49713 R-MMU-425822 https://reactome.org/PathwayBrowser/#/R-MMU-425822 K+-independent Li+/Ca2+ exchanger transport IEA Mus musculus 49713 R-MMU-8953499 https://reactome.org/PathwayBrowser/#/R-MMU-8953499 IMPAD1 hydrolyses PAP to AMP IEA Mus musculus 49713 R-RNO-425822 https://reactome.org/PathwayBrowser/#/R-RNO-425822 K+-independent Li+/Ca2+ exchanger transport IEA Rattus norvegicus 49713 R-RNO-8953499 https://reactome.org/PathwayBrowser/#/R-RNO-8953499 IMPAD1 hydrolyses PAP to AMP IEA Rattus norvegicus 49713 R-SCE-425822 https://reactome.org/PathwayBrowser/#/R-SCE-425822 K+-independent Li+/Ca2+ exchanger transport IEA Saccharomyces cerevisiae 49713 R-SPO-425822 https://reactome.org/PathwayBrowser/#/R-SPO-425822 K+-independent Li+/Ca2+ exchanger transport IEA Schizosaccharomyces pombe 49713 R-SSC-425822 https://reactome.org/PathwayBrowser/#/R-SSC-425822 K+-independent Li+/Ca2+ exchanger transport IEA Sus scrofa 49713 R-SSC-8953499 https://reactome.org/PathwayBrowser/#/R-SSC-8953499 IMPAD1 hydrolyses PAP to AMP IEA Sus scrofa 49713 R-XTR-8953499 https://reactome.org/PathwayBrowser/#/R-XTR-8953499 IMPAD1 hydrolyses PAP to AMP IEA Xenopus tropicalis 49883 R-BTA-6793591 https://reactome.org/PathwayBrowser/#/R-BTA-6793591 LIAS synthesizes lipoyl-GCSH IEA Bos taurus 49883 R-BTA-8878815 https://reactome.org/PathwayBrowser/#/R-BTA-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Bos taurus 49883 R-BTA-9854984 https://reactome.org/PathwayBrowser/#/R-BTA-9854984 Transfer of Fe-S clusters to SDHB IEA Bos taurus 49883 R-CEL-8878815 https://reactome.org/PathwayBrowser/#/R-CEL-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Caenorhabditis elegans 49883 R-CFA-6793591 https://reactome.org/PathwayBrowser/#/R-CFA-6793591 LIAS synthesizes lipoyl-GCSH IEA Canis familiaris 49883 R-CFA-8878815 https://reactome.org/PathwayBrowser/#/R-CFA-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Canis familiaris 49883 R-DDI-8878815 https://reactome.org/PathwayBrowser/#/R-DDI-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Dictyostelium discoideum 49883 R-DME-6793591 https://reactome.org/PathwayBrowser/#/R-DME-6793591 LIAS synthesizes lipoyl-GCSH IEA Drosophila melanogaster 49883 R-DME-8878815 https://reactome.org/PathwayBrowser/#/R-DME-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Drosophila melanogaster 49883 R-DRE-6793591 https://reactome.org/PathwayBrowser/#/R-DRE-6793591 LIAS synthesizes lipoyl-GCSH IEA Danio rerio 49883 R-GGA-6793591 https://reactome.org/PathwayBrowser/#/R-GGA-6793591 LIAS synthesizes lipoyl-GCSH IEA Gallus gallus 49883 R-GGA-8878815 https://reactome.org/PathwayBrowser/#/R-GGA-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Gallus gallus 49883 R-HSA-2564824 https://reactome.org/PathwayBrowser/#/R-HSA-2564824 NADPH reduces NDOR1:CIAPIN1 IEA Homo sapiens 49883 R-HSA-2564826 https://reactome.org/PathwayBrowser/#/R-HSA-2564826 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold IEA Homo sapiens 49883 R-HSA-2564828 https://reactome.org/PathwayBrowser/#/R-HSA-2564828 CIA Targeting Complex transfers 4Fe-4S cluster to apoproteins IEA Homo sapiens 49883 R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 49883 R-HSA-6786571 https://reactome.org/PathwayBrowser/#/R-HSA-6786571 CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37 TAS Homo sapiens 49883 R-HSA-6793591 https://reactome.org/PathwayBrowser/#/R-HSA-6793591 LIAS synthesizes lipoyl-GCSH TAS Homo sapiens 49883 R-HSA-8878815 https://reactome.org/PathwayBrowser/#/R-HSA-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 TAS Homo sapiens 49883 R-HSA-9854984 https://reactome.org/PathwayBrowser/#/R-HSA-9854984 Transfer of Fe-S clusters to SDHB TAS Homo sapiens 49883 R-MMU-6793591 https://reactome.org/PathwayBrowser/#/R-MMU-6793591 LIAS synthesizes lipoyl-GCSH IEA Mus musculus 49883 R-MMU-8878815 https://reactome.org/PathwayBrowser/#/R-MMU-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Mus musculus 49883 R-MMU-9854984 https://reactome.org/PathwayBrowser/#/R-MMU-9854984 Transfer of Fe-S clusters to SDHB IEA Mus musculus 49883 R-RNO-6793591 https://reactome.org/PathwayBrowser/#/R-RNO-6793591 LIAS synthesizes lipoyl-GCSH IEA Rattus norvegicus 49883 R-RNO-8878815 https://reactome.org/PathwayBrowser/#/R-RNO-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Rattus norvegicus 49883 R-SCE-2564817 https://reactome.org/PathwayBrowser/#/R-SCE-2564817 CIA Targeting Complex transfers 4Fe-4S clusters to apoproteins TAS Saccharomyces cerevisiae 49883 R-SCE-2564819 https://reactome.org/PathwayBrowser/#/R-SCE-2564819 NADPH reduces TAH18:DRE2 TAS Saccharomyces cerevisiae 49883 R-SCE-2564822 https://reactome.org/PathwayBrowser/#/R-SCE-2564822 4Fe-4S cluster assembles on CFD1:NBP35 scaffold TAS Saccharomyces cerevisiae 49883 R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 49883 R-SCE-8878815 https://reactome.org/PathwayBrowser/#/R-SCE-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Saccharomyces cerevisiae 49883 R-SPO-8878815 https://reactome.org/PathwayBrowser/#/R-SPO-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Schizosaccharomyces pombe 49883 R-SSC-6793591 https://reactome.org/PathwayBrowser/#/R-SSC-6793591 LIAS synthesizes lipoyl-GCSH IEA Sus scrofa 49883 R-SSC-8878815 https://reactome.org/PathwayBrowser/#/R-SSC-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Sus scrofa 49883 R-SSC-9854984 https://reactome.org/PathwayBrowser/#/R-SSC-9854984 Transfer of Fe-S clusters to SDHB IEA Sus scrofa 49960 R-HSA-1220610 https://reactome.org/PathwayBrowser/#/R-HSA-1220610 Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants TAS Homo sapiens 50042 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 50042 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 50042 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 50042 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 50042 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 50042 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 50042 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 50042 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 50042 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 50042 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 50042 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 50042 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 50042 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 50042 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 50042 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 50042 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 50042 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 50042 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 50042 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 50042 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 50042 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 50042 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 50042 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 50042 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 50042 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 50042 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 50042 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 50042 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 50042 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 50042 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 50042 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 50042 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 50091 R-HSA-1222384 https://reactome.org/PathwayBrowser/#/R-HSA-1222384 Glutathione scavenges nitrosyl TAS Homo sapiens 50091 R-HSA-1222712 https://reactome.org/PathwayBrowser/#/R-HSA-1222712 Nitrosoglutathione gets cleaved to Cys(NO)-Gly TAS Homo sapiens 50114 R-BTA-1254386 https://reactome.org/PathwayBrowser/#/R-BTA-1254386 ERBB4s80 forms a complex with estrogen receptor ESR1 IEA Bos taurus 50114 R-BTA-2316434 https://reactome.org/PathwayBrowser/#/R-BTA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 50114 R-BTA-8931981 https://reactome.org/PathwayBrowser/#/R-BTA-8931981 RUNX1 binds ESR1 IEA Bos taurus 50114 R-BTA-8939201 https://reactome.org/PathwayBrowser/#/R-BTA-8939201 ESR dimerizes IEA Bos taurus 50114 R-BTA-8939204 https://reactome.org/PathwayBrowser/#/R-BTA-8939204 ESTG binds ESR1:chaperone complex IEA Bos taurus 50114 R-BTA-9011949 https://reactome.org/PathwayBrowser/#/R-BTA-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Bos taurus 50114 R-BTA-9011952 https://reactome.org/PathwayBrowser/#/R-BTA-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Bos taurus 50114 R-BTA-9011981 https://reactome.org/PathwayBrowser/#/R-BTA-9011981 EP300 is recruited to MYC and BCL2 genes IEA Bos taurus 50114 R-BTA-9011983 https://reactome.org/PathwayBrowser/#/R-BTA-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Bos taurus 50114 R-BTA-9011984 https://reactome.org/PathwayBrowser/#/R-BTA-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Bos taurus 50114 R-BTA-9011985 https://reactome.org/PathwayBrowser/#/R-BTA-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Bos taurus 50114 R-BTA-9012000 https://reactome.org/PathwayBrowser/#/R-BTA-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Bos taurus 50114 R-BTA-9012315 https://reactome.org/PathwayBrowser/#/R-BTA-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Bos taurus 50114 R-BTA-9012319 https://reactome.org/PathwayBrowser/#/R-BTA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Bos taurus 50114 R-BTA-9018499 https://reactome.org/PathwayBrowser/#/R-BTA-9018499 ESR1:ESTG and EP300 are recruited to TFF3 promoter IEA Bos taurus 50114 R-BTA-9021170 https://reactome.org/PathwayBrowser/#/R-BTA-9021170 Estrogen stimulates dimerization of plasma membrane estrogen receptors IEA Bos taurus 50114 R-BTA-9021596 https://reactome.org/PathwayBrowser/#/R-BTA-9021596 Membrane estrogen receptors bind SRC IEA Bos taurus 50114 R-BTA-9021600 https://reactome.org/PathwayBrowser/#/R-BTA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Bos taurus 50114 R-BTA-9021601 https://reactome.org/PathwayBrowser/#/R-BTA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Bos taurus 50114 R-BTA-9021609 https://reactome.org/PathwayBrowser/#/R-BTA-9021609 ESR-associated SRC autophosphorylates IEA Bos taurus 50114 R-BTA-9021660 https://reactome.org/PathwayBrowser/#/R-BTA-9021660 PI3K binds membrane-associated estrogen receptors IEA Bos taurus 50114 R-BTA-9023840 https://reactome.org/PathwayBrowser/#/R-BTA-9023840 HATs and coactivators are recruited to the CTSD gene IEA Bos taurus 50114 R-BTA-9038052 https://reactome.org/PathwayBrowser/#/R-BTA-9038052 GREB1 binds ESR1:ESTG and co-activators IEA Bos taurus 50114 R-BTA-9038161 https://reactome.org/PathwayBrowser/#/R-BTA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Bos taurus 50114 R-BTA-9038163 https://reactome.org/PathwayBrowser/#/R-BTA-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Bos taurus 50114 R-BTA-9624272 https://reactome.org/PathwayBrowser/#/R-BTA-9624272 MMPs cleave HB-EGF IEA Bos taurus 50114 R-BTA-9625814 https://reactome.org/PathwayBrowser/#/R-BTA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Bos taurus 50114 R-BTA-9632182 https://reactome.org/PathwayBrowser/#/R-BTA-9632182 PRMT1 methylates ESRs IEA Bos taurus 50114 R-BTA-9632412 https://reactome.org/PathwayBrowser/#/R-BTA-9632412 PTK2 is recruited to methylated ESR1 IEA Bos taurus 50114 R-BTA-9633044 https://reactome.org/PathwayBrowser/#/R-BTA-9633044 ESR binds STRN IEA Bos taurus 50114 R-BTA-9634584 https://reactome.org/PathwayBrowser/#/R-BTA-9634584 Estrogen receptor binds IGF1R and SHC1 in response to estrogen IEA Bos taurus 50114 R-BTA-9709547 https://reactome.org/PathwayBrowser/#/R-BTA-9709547 ESTG binds ESR2:chaperone complex IEA Bos taurus 50114 R-CEL-2316434 https://reactome.org/PathwayBrowser/#/R-CEL-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 50114 R-CEL-9012319 https://reactome.org/PathwayBrowser/#/R-CEL-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Caenorhabditis elegans 50114 R-CEL-9632412 https://reactome.org/PathwayBrowser/#/R-CEL-9632412 PTK2 is recruited to methylated ESR1 IEA Caenorhabditis elegans 50114 R-CFA-1254386 https://reactome.org/PathwayBrowser/#/R-CFA-1254386 ERBB4s80 forms a complex with estrogen receptor ESR1 IEA Canis familiaris 50114 R-CFA-2316434 https://reactome.org/PathwayBrowser/#/R-CFA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 50114 R-CFA-374207 https://reactome.org/PathwayBrowser/#/R-CFA-374207 G protein-coupled estrogen receptor 1 binds estrogen non-classically IEA Canis familiaris 50114 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 50114 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 50114 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 50114 R-CFA-8931981 https://reactome.org/PathwayBrowser/#/R-CFA-8931981 RUNX1 binds ESR1 IEA Canis familiaris 50114 R-CFA-8939201 https://reactome.org/PathwayBrowser/#/R-CFA-8939201 ESR dimerizes IEA Canis familiaris 50114 R-CFA-9009371 https://reactome.org/PathwayBrowser/#/R-CFA-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Canis familiaris 50114 R-CFA-9011949 https://reactome.org/PathwayBrowser/#/R-CFA-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Canis familiaris 50114 R-CFA-9011952 https://reactome.org/PathwayBrowser/#/R-CFA-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Canis familiaris 50114 R-CFA-9011981 https://reactome.org/PathwayBrowser/#/R-CFA-9011981 EP300 is recruited to MYC and BCL2 genes IEA Canis familiaris 50114 R-CFA-9011983 https://reactome.org/PathwayBrowser/#/R-CFA-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Canis familiaris 50114 R-CFA-9011984 https://reactome.org/PathwayBrowser/#/R-CFA-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Canis familiaris 50114 R-CFA-9011985 https://reactome.org/PathwayBrowser/#/R-CFA-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Canis familiaris 50114 R-CFA-9012000 https://reactome.org/PathwayBrowser/#/R-CFA-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Canis familiaris 50114 R-CFA-9012315 https://reactome.org/PathwayBrowser/#/R-CFA-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Canis familiaris 50114 R-CFA-9012319 https://reactome.org/PathwayBrowser/#/R-CFA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Canis familiaris 50114 R-CFA-9018499 https://reactome.org/PathwayBrowser/#/R-CFA-9018499 ESR1:ESTG and EP300 are recruited to TFF3 promoter IEA Canis familiaris 50114 R-CFA-9021170 https://reactome.org/PathwayBrowser/#/R-CFA-9021170 Estrogen stimulates dimerization of plasma membrane estrogen receptors IEA Canis familiaris 50114 R-CFA-9021596 https://reactome.org/PathwayBrowser/#/R-CFA-9021596 Membrane estrogen receptors bind SRC IEA Canis familiaris 50114 R-CFA-9021600 https://reactome.org/PathwayBrowser/#/R-CFA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Canis familiaris 50114 R-CFA-9021601 https://reactome.org/PathwayBrowser/#/R-CFA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Canis familiaris 50114 R-CFA-9021609 https://reactome.org/PathwayBrowser/#/R-CFA-9021609 ESR-associated SRC autophosphorylates IEA Canis familiaris 50114 R-CFA-9021660 https://reactome.org/PathwayBrowser/#/R-CFA-9021660 PI3K binds membrane-associated estrogen receptors IEA Canis familiaris 50114 R-CFA-9023840 https://reactome.org/PathwayBrowser/#/R-CFA-9023840 HATs and coactivators are recruited to the CTSD gene IEA Canis familiaris 50114 R-CFA-9036301 https://reactome.org/PathwayBrowser/#/R-CFA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Canis familiaris 50114 R-CFA-9036307 https://reactome.org/PathwayBrowser/#/R-CFA-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Canis familiaris 50114 R-CFA-9038052 https://reactome.org/PathwayBrowser/#/R-CFA-9038052 GREB1 binds ESR1:ESTG and co-activators IEA Canis familiaris 50114 R-CFA-9624272 https://reactome.org/PathwayBrowser/#/R-CFA-9624272 MMPs cleave HB-EGF IEA Canis familiaris 50114 R-CFA-9625814 https://reactome.org/PathwayBrowser/#/R-CFA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Canis familiaris 50114 R-CFA-9632182 https://reactome.org/PathwayBrowser/#/R-CFA-9632182 PRMT1 methylates ESRs IEA Canis familiaris 50114 R-CFA-9632412 https://reactome.org/PathwayBrowser/#/R-CFA-9632412 PTK2 is recruited to methylated ESR1 IEA Canis familiaris 50114 R-CFA-9633044 https://reactome.org/PathwayBrowser/#/R-CFA-9633044 ESR binds STRN IEA Canis familiaris 50114 R-CFA-9634584 https://reactome.org/PathwayBrowser/#/R-CFA-9634584 Estrogen receptor binds IGF1R and SHC1 in response to estrogen IEA Canis familiaris 50114 R-DDI-9012319 https://reactome.org/PathwayBrowser/#/R-DDI-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Dictyostelium discoideum 50114 R-DME-1254386 https://reactome.org/PathwayBrowser/#/R-DME-1254386 ERBB4s80 forms a complex with estrogen receptor ESR1 IEA Drosophila melanogaster 50114 R-DME-2316434 https://reactome.org/PathwayBrowser/#/R-DME-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 50114 R-DME-8931981 https://reactome.org/PathwayBrowser/#/R-DME-8931981 RUNX1 binds ESR1 IEA Drosophila melanogaster 50114 R-DME-8939201 https://reactome.org/PathwayBrowser/#/R-DME-8939201 ESR dimerizes IEA Drosophila melanogaster 50114 R-DME-8939204 https://reactome.org/PathwayBrowser/#/R-DME-8939204 ESTG binds ESR1:chaperone complex IEA Drosophila melanogaster 50114 R-DME-9009371 https://reactome.org/PathwayBrowser/#/R-DME-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Drosophila melanogaster 50114 R-DME-9011949 https://reactome.org/PathwayBrowser/#/R-DME-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Drosophila melanogaster 50114 R-DME-9011952 https://reactome.org/PathwayBrowser/#/R-DME-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Drosophila melanogaster 50114 R-DME-9011981 https://reactome.org/PathwayBrowser/#/R-DME-9011981 EP300 is recruited to MYC and BCL2 genes IEA Drosophila melanogaster 50114 R-DME-9011983 https://reactome.org/PathwayBrowser/#/R-DME-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Drosophila melanogaster 50114 R-DME-9011984 https://reactome.org/PathwayBrowser/#/R-DME-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Drosophila melanogaster 50114 R-DME-9011985 https://reactome.org/PathwayBrowser/#/R-DME-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Drosophila melanogaster 50114 R-DME-9012315 https://reactome.org/PathwayBrowser/#/R-DME-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Drosophila melanogaster 50114 R-DME-9012319 https://reactome.org/PathwayBrowser/#/R-DME-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Drosophila melanogaster 50114 R-DME-9018499 https://reactome.org/PathwayBrowser/#/R-DME-9018499 ESR1:ESTG and EP300 are recruited to TFF3 promoter IEA Drosophila melanogaster 50114 R-DME-9021170 https://reactome.org/PathwayBrowser/#/R-DME-9021170 Estrogen stimulates dimerization of plasma membrane estrogen receptors IEA Drosophila melanogaster 50114 R-DME-9021596 https://reactome.org/PathwayBrowser/#/R-DME-9021596 Membrane estrogen receptors bind SRC IEA Drosophila melanogaster 50114 R-DME-9021600 https://reactome.org/PathwayBrowser/#/R-DME-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Drosophila melanogaster 50114 R-DME-9021601 https://reactome.org/PathwayBrowser/#/R-DME-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Drosophila melanogaster 50114 R-DME-9021609 https://reactome.org/PathwayBrowser/#/R-DME-9021609 ESR-associated SRC autophosphorylates IEA Drosophila melanogaster 50114 R-DME-9023840 https://reactome.org/PathwayBrowser/#/R-DME-9023840 HATs and coactivators are recruited to the CTSD gene IEA Drosophila melanogaster 50114 R-DME-9038161 https://reactome.org/PathwayBrowser/#/R-DME-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Drosophila melanogaster 50114 R-DME-9625814 https://reactome.org/PathwayBrowser/#/R-DME-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Drosophila melanogaster 50114 R-DME-9632182 https://reactome.org/PathwayBrowser/#/R-DME-9632182 PRMT1 methylates ESRs IEA Drosophila melanogaster 50114 R-DME-9633044 https://reactome.org/PathwayBrowser/#/R-DME-9633044 ESR binds STRN IEA Drosophila melanogaster 50114 R-DME-9634584 https://reactome.org/PathwayBrowser/#/R-DME-9634584 Estrogen receptor binds IGF1R and SHC1 in response to estrogen IEA Drosophila melanogaster 50114 R-DME-9709547 https://reactome.org/PathwayBrowser/#/R-DME-9709547 ESTG binds ESR2:chaperone complex IEA Drosophila melanogaster 50114 R-DRE-1254386 https://reactome.org/PathwayBrowser/#/R-DRE-1254386 ERBB4s80 forms a complex with estrogen receptor ESR1 IEA Danio rerio 50114 R-DRE-2316434 https://reactome.org/PathwayBrowser/#/R-DRE-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 50114 R-DRE-374207 https://reactome.org/PathwayBrowser/#/R-DRE-374207 G protein-coupled estrogen receptor 1 binds estrogen non-classically IEA Danio rerio 50114 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 50114 R-DRE-8939201 https://reactome.org/PathwayBrowser/#/R-DRE-8939201 ESR dimerizes IEA Danio rerio 50114 R-DRE-8939204 https://reactome.org/PathwayBrowser/#/R-DRE-8939204 ESTG binds ESR1:chaperone complex IEA Danio rerio 50114 R-DRE-9011949 https://reactome.org/PathwayBrowser/#/R-DRE-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Danio rerio 50114 R-DRE-9011952 https://reactome.org/PathwayBrowser/#/R-DRE-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Danio rerio 50114 R-DRE-9011983 https://reactome.org/PathwayBrowser/#/R-DRE-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Danio rerio 50114 R-DRE-9021170 https://reactome.org/PathwayBrowser/#/R-DRE-9021170 Estrogen stimulates dimerization of plasma membrane estrogen receptors IEA Danio rerio 50114 R-DRE-9021596 https://reactome.org/PathwayBrowser/#/R-DRE-9021596 Membrane estrogen receptors bind SRC IEA Danio rerio 50114 R-DRE-9021609 https://reactome.org/PathwayBrowser/#/R-DRE-9021609 ESR-associated SRC autophosphorylates IEA Danio rerio 50114 R-DRE-9021660 https://reactome.org/PathwayBrowser/#/R-DRE-9021660 PI3K binds membrane-associated estrogen receptors IEA Danio rerio 50114 R-DRE-9038163 https://reactome.org/PathwayBrowser/#/R-DRE-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Danio rerio 50114 R-DRE-9633044 https://reactome.org/PathwayBrowser/#/R-DRE-9633044 ESR binds STRN IEA Danio rerio 50114 R-DRE-9709547 https://reactome.org/PathwayBrowser/#/R-DRE-9709547 ESTG binds ESR2:chaperone complex IEA Danio rerio 50114 R-GGA-1254386 https://reactome.org/PathwayBrowser/#/R-GGA-1254386 ERBB4s80 forms a complex with estrogen receptor ESR1 IEA Gallus gallus 50114 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 50114 R-GGA-374207 https://reactome.org/PathwayBrowser/#/R-GGA-374207 G protein-coupled estrogen receptor 1 binds estrogen non-classically IEA Gallus gallus 50114 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 50114 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 50114 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 50114 R-GGA-8931981 https://reactome.org/PathwayBrowser/#/R-GGA-8931981 RUNX1 binds ESR1 IEA Gallus gallus 50114 R-GGA-8939201 https://reactome.org/PathwayBrowser/#/R-GGA-8939201 ESR dimerizes IEA Gallus gallus 50114 R-GGA-8939204 https://reactome.org/PathwayBrowser/#/R-GGA-8939204 ESTG binds ESR1:chaperone complex IEA Gallus gallus 50114 R-GGA-9009371 https://reactome.org/PathwayBrowser/#/R-GGA-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Gallus gallus 50114 R-GGA-9011949 https://reactome.org/PathwayBrowser/#/R-GGA-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Gallus gallus 50114 R-GGA-9011952 https://reactome.org/PathwayBrowser/#/R-GGA-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Gallus gallus 50114 R-GGA-9011981 https://reactome.org/PathwayBrowser/#/R-GGA-9011981 EP300 is recruited to MYC and BCL2 genes IEA Gallus gallus 50114 R-GGA-9011983 https://reactome.org/PathwayBrowser/#/R-GGA-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Gallus gallus 50114 R-GGA-9011984 https://reactome.org/PathwayBrowser/#/R-GGA-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Gallus gallus 50114 R-GGA-9011985 https://reactome.org/PathwayBrowser/#/R-GGA-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Gallus gallus 50114 R-GGA-9012000 https://reactome.org/PathwayBrowser/#/R-GGA-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Gallus gallus 50114 R-GGA-9012315 https://reactome.org/PathwayBrowser/#/R-GGA-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Gallus gallus 50114 R-GGA-9012319 https://reactome.org/PathwayBrowser/#/R-GGA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Gallus gallus 50114 R-GGA-9018499 https://reactome.org/PathwayBrowser/#/R-GGA-9018499 ESR1:ESTG and EP300 are recruited to TFF3 promoter IEA Gallus gallus 50114 R-GGA-9021170 https://reactome.org/PathwayBrowser/#/R-GGA-9021170 Estrogen stimulates dimerization of plasma membrane estrogen receptors IEA Gallus gallus 50114 R-GGA-9021596 https://reactome.org/PathwayBrowser/#/R-GGA-9021596 Membrane estrogen receptors bind SRC IEA Gallus gallus 50114 R-GGA-9021600 https://reactome.org/PathwayBrowser/#/R-GGA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Gallus gallus 50114 R-GGA-9021601 https://reactome.org/PathwayBrowser/#/R-GGA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Gallus gallus 50114 R-GGA-9021609 https://reactome.org/PathwayBrowser/#/R-GGA-9021609 ESR-associated SRC autophosphorylates IEA Gallus gallus 50114 R-GGA-9021660 https://reactome.org/PathwayBrowser/#/R-GGA-9021660 PI3K binds membrane-associated estrogen receptors IEA Gallus gallus 50114 R-GGA-9036301 https://reactome.org/PathwayBrowser/#/R-GGA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Gallus gallus 50114 R-GGA-9036307 https://reactome.org/PathwayBrowser/#/R-GGA-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Gallus gallus 50114 R-GGA-9038052 https://reactome.org/PathwayBrowser/#/R-GGA-9038052 GREB1 binds ESR1:ESTG and co-activators IEA Gallus gallus 50114 R-GGA-9038161 https://reactome.org/PathwayBrowser/#/R-GGA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Gallus gallus 50114 R-GGA-9038163 https://reactome.org/PathwayBrowser/#/R-GGA-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Gallus gallus 50114 R-GGA-9624272 https://reactome.org/PathwayBrowser/#/R-GGA-9624272 MMPs cleave HB-EGF IEA Gallus gallus 50114 R-GGA-9625814 https://reactome.org/PathwayBrowser/#/R-GGA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Gallus gallus 50114 R-GGA-9632412 https://reactome.org/PathwayBrowser/#/R-GGA-9632412 PTK2 is recruited to methylated ESR1 IEA Gallus gallus 50114 R-GGA-9633044 https://reactome.org/PathwayBrowser/#/R-GGA-9633044 ESR binds STRN IEA Gallus gallus 50114 R-GGA-9634584 https://reactome.org/PathwayBrowser/#/R-GGA-9634584 Estrogen receptor binds IGF1R and SHC1 in response to estrogen IEA Gallus gallus 50114 R-GGA-9709547 https://reactome.org/PathwayBrowser/#/R-GGA-9709547 ESTG binds ESR2:chaperone complex IEA Gallus gallus 50114 R-HSA-1254386 https://reactome.org/PathwayBrowser/#/R-HSA-1254386 ERBB4s80 forms a complex with estrogen receptor ESR1 TAS Homo sapiens 50114 R-HSA-1254392 https://reactome.org/PathwayBrowser/#/R-HSA-1254392 PGR gene expression is stimulated by ERBB4s80:ESR1:estrogen TAS Homo sapiens 50114 R-HSA-2316434 https://reactome.org/PathwayBrowser/#/R-HSA-2316434 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 50114 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 50114 R-HSA-374207 https://reactome.org/PathwayBrowser/#/R-HSA-374207 G protein-coupled estrogen receptor 1 binds estrogen non-classically TAS Homo sapiens 50114 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 50114 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 50114 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 50114 R-HSA-8931981 https://reactome.org/PathwayBrowser/#/R-HSA-8931981 RUNX1 binds ESR1 TAS Homo sapiens 50114 R-HSA-8932020 https://reactome.org/PathwayBrowser/#/R-HSA-8932020 GPAM gene expression is stimulated by RUNX1 and ESR1 TAS Homo sapiens 50114 R-HSA-8932021 https://reactome.org/PathwayBrowser/#/R-HSA-8932021 RUNX1 and ESR1 bind the GPAM gene enhancer TAS Homo sapiens 50114 R-HSA-8932033 https://reactome.org/PathwayBrowser/#/R-HSA-8932033 KCTD6 gene expression is stimulated by RUNX1 and ESR1 TAS Homo sapiens 50114 R-HSA-8932037 https://reactome.org/PathwayBrowser/#/R-HSA-8932037 RUNX1 and ESR1 bind the KCTD6 gene enhancer TAS Homo sapiens 50114 R-HSA-8932070 https://reactome.org/PathwayBrowser/#/R-HSA-8932070 ESR1 binds the AXIN1 gene TAS Homo sapiens 50114 R-HSA-8932076 https://reactome.org/PathwayBrowser/#/R-HSA-8932076 AXIN1 gene expression is inhibited by ESR1 and stimulated by RUNX1 TAS Homo sapiens 50114 R-HSA-8932084 https://reactome.org/PathwayBrowser/#/R-HSA-8932084 RUNX1 and ESR1 bind the AXIN1 gene TAS Homo sapiens 50114 R-HSA-8939201 https://reactome.org/PathwayBrowser/#/R-HSA-8939201 ESR dimerizes TAS Homo sapiens 50114 R-HSA-8939203 https://reactome.org/PathwayBrowser/#/R-HSA-8939203 HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex TAS Homo sapiens 50114 R-HSA-8939204 https://reactome.org/PathwayBrowser/#/R-HSA-8939204 ESTG binds ESR1:chaperone complex TAS Homo sapiens 50114 R-HSA-8939205 https://reactome.org/PathwayBrowser/#/R-HSA-8939205 ESTG translocates to the nucleus TAS Homo sapiens 50114 R-HSA-8939900 https://reactome.org/PathwayBrowser/#/R-HSA-8939900 RUNX2 gene expression from proximal (P2) promoter is stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and inhibited by ESRRA:PPARG1CB and DEXA:NR3C1 IEA Homo sapiens 50114 R-HSA-8939904 https://reactome.org/PathwayBrowser/#/R-HSA-8939904 Activated ESR1 binds the RUNX2 gene promoter TAS Homo sapiens 50114 R-HSA-8954199 https://reactome.org/PathwayBrowser/#/R-HSA-8954199 CXCL12 gene expression is stimulated by ERBB4s80:ESR1:estrogen TAS Homo sapiens 50114 R-HSA-8954207 https://reactome.org/PathwayBrowser/#/R-HSA-8954207 ERBB4s80:ESR1 binds CXCL12 gene promoter TAS Homo sapiens 50114 R-HSA-8954208 https://reactome.org/PathwayBrowser/#/R-HSA-8954208 ERBB4s80:ESR1 binds PGR gene promoter TAS Homo sapiens 50114 R-HSA-9009371 https://reactome.org/PathwayBrowser/#/R-HSA-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter TAS Homo sapiens 50114 R-HSA-9009378 https://reactome.org/PathwayBrowser/#/R-HSA-9009378 Estrogen-responsive CCND1 gene expression TAS Homo sapiens 50114 R-HSA-9011941 https://reactome.org/PathwayBrowser/#/R-HSA-9011941 Estrogen-responsive BCL2 gene expression TAS Homo sapiens 50114 R-HSA-9011949 https://reactome.org/PathwayBrowser/#/R-HSA-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers TAS Homo sapiens 50114 R-HSA-9011950 https://reactome.org/PathwayBrowser/#/R-HSA-9011950 Estrogen-responsive GREB1 gene transcription TAS Homo sapiens 50114 R-HSA-9011952 https://reactome.org/PathwayBrowser/#/R-HSA-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers TAS Homo sapiens 50114 R-HSA-9011966 https://reactome.org/PathwayBrowser/#/R-HSA-9011966 Estrogen-responsive KDM4B gene expression TAS Homo sapiens 50114 R-HSA-9011971 https://reactome.org/PathwayBrowser/#/R-HSA-9011971 Estrogen-responsive MYB gene expression TAS Homo sapiens 50114 R-HSA-9011975 https://reactome.org/PathwayBrowser/#/R-HSA-9011975 Estrogen-responsive MYC gene expression TAS Homo sapiens 50114 R-HSA-9011981 https://reactome.org/PathwayBrowser/#/R-HSA-9011981 EP300 is recruited to MYC and BCL2 genes TAS Homo sapiens 50114 R-HSA-9011983 https://reactome.org/PathwayBrowser/#/R-HSA-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes TAS Homo sapiens 50114 R-HSA-9011984 https://reactome.org/PathwayBrowser/#/R-HSA-9011984 KDM1A is recruited to MYC and BCL2 genes TAS Homo sapiens 50114 R-HSA-9011985 https://reactome.org/PathwayBrowser/#/R-HSA-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen TAS Homo sapiens 50114 R-HSA-9011997 https://reactome.org/PathwayBrowser/#/R-HSA-9011997 ESR1:ESTG, JUND:FOSB and Cohesin Complex bind distal enhancer elements in MYC gene promoter TAS Homo sapiens 50114 R-HSA-9012000 https://reactome.org/PathwayBrowser/#/R-HSA-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter TAS Homo sapiens 50114 R-HSA-9012205 https://reactome.org/PathwayBrowser/#/R-HSA-9012205 Estrogen-responsive CHD1 gene transcription TAS Homo sapiens 50114 R-HSA-9012209 https://reactome.org/PathwayBrowser/#/R-HSA-9012209 Estrogen-responsive KPNA2 gene transcription TAS Homo sapiens 50114 R-HSA-9012315 https://reactome.org/PathwayBrowser/#/R-HSA-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene TAS Homo sapiens 50114 R-HSA-9012319 https://reactome.org/PathwayBrowser/#/R-HSA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD TAS Homo sapiens 50114 R-HSA-9018325 https://reactome.org/PathwayBrowser/#/R-HSA-9018325 ESR1:ESTG binds CXXC5 gene TAS Homo sapiens 50114 R-HSA-9018334 https://reactome.org/PathwayBrowser/#/R-HSA-9018334 Estrogen-responsive CXXC5 gene expresion TAS Homo sapiens 50114 R-HSA-9018497 https://reactome.org/PathwayBrowser/#/R-HSA-9018497 Estrogen-responsive TFF3 gene expression TAS Homo sapiens 50114 R-HSA-9018499 https://reactome.org/PathwayBrowser/#/R-HSA-9018499 ESR1:ESTG and EP300 are recruited to TFF3 promoter TAS Homo sapiens 50114 R-HSA-9018503 https://reactome.org/PathwayBrowser/#/R-HSA-9018503 ESR1:ESTG bind the EBAG9 5' region TAS Homo sapiens 50114 R-HSA-9018505 https://reactome.org/PathwayBrowser/#/R-HSA-9018505 Estrogen-responsive EBAG9 gene expression TAS Homo sapiens 50114 R-HSA-9021170 https://reactome.org/PathwayBrowser/#/R-HSA-9021170 Estrogen stimulates dimerization of plasma membrane estrogen receptors TAS Homo sapiens 50114 R-HSA-9021596 https://reactome.org/PathwayBrowser/#/R-HSA-9021596 Membrane estrogen receptors bind SRC TAS Homo sapiens 50114 R-HSA-9021600 https://reactome.org/PathwayBrowser/#/R-HSA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors TAS Homo sapiens 50114 R-HSA-9021601 https://reactome.org/PathwayBrowser/#/R-HSA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG TAS Homo sapiens 50114 R-HSA-9021609 https://reactome.org/PathwayBrowser/#/R-HSA-9021609 ESR-associated SRC autophosphorylates TAS Homo sapiens 50114 R-HSA-9021660 https://reactome.org/PathwayBrowser/#/R-HSA-9021660 PI3K binds membrane-associated estrogen receptors TAS Homo sapiens 50114 R-HSA-9023840 https://reactome.org/PathwayBrowser/#/R-HSA-9023840 HATs and coactivators are recruited to the CTSD gene TAS Homo sapiens 50114 R-HSA-9023845 https://reactome.org/PathwayBrowser/#/R-HSA-9023845 ESR1:ESTG binds to proximal and distal regions of the CTSD promoter TAS Homo sapiens 50114 R-HSA-9023846 https://reactome.org/PathwayBrowser/#/R-HSA-9023846 Estrogen-responsive CTSD expression TAS Homo sapiens 50114 R-HSA-9027670 https://reactome.org/PathwayBrowser/#/R-HSA-9027670 ESTG binding induces ESR depalmitoylation TAS Homo sapiens 50114 R-HSA-9036301 https://reactome.org/PathwayBrowser/#/R-HSA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s TAS Homo sapiens 50114 R-HSA-9036307 https://reactome.org/PathwayBrowser/#/R-HSA-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG TAS Homo sapiens 50114 R-HSA-9036308 https://reactome.org/PathwayBrowser/#/R-HSA-9036308 ESTG-stimulated dissociation of GPER:heterotrimeric G-protein (s) complex TAS Homo sapiens 50114 R-HSA-9038052 https://reactome.org/PathwayBrowser/#/R-HSA-9038052 GREB1 binds ESR1:ESTG and co-activators TAS Homo sapiens 50114 R-HSA-9038161 https://reactome.org/PathwayBrowser/#/R-HSA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG TAS Homo sapiens 50114 R-HSA-9038163 https://reactome.org/PathwayBrowser/#/R-HSA-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators TAS Homo sapiens 50114 R-HSA-9612671 https://reactome.org/PathwayBrowser/#/R-HSA-9612671 ERBB4 gene expression is stimulated by ERBB4s80:ESR1 TAS Homo sapiens 50114 R-HSA-9612672 https://reactome.org/PathwayBrowser/#/R-HSA-9612672 ERBB4s80:ESR1 binds ERBB4 gene promoter TAS Homo sapiens 50114 R-HSA-9624272 https://reactome.org/PathwayBrowser/#/R-HSA-9624272 MMPs cleave HB-EGF TAS Homo sapiens 50114 R-HSA-9625814 https://reactome.org/PathwayBrowser/#/R-HSA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation TAS Homo sapiens 50114 R-HSA-9632182 https://reactome.org/PathwayBrowser/#/R-HSA-9632182 PRMT1 methylates ESRs TAS Homo sapiens 50114 R-HSA-9632412 https://reactome.org/PathwayBrowser/#/R-HSA-9632412 PTK2 is recruited to methylated ESR1 TAS Homo sapiens 50114 R-HSA-9633044 https://reactome.org/PathwayBrowser/#/R-HSA-9633044 ESR binds STRN TAS Homo sapiens 50114 R-HSA-9634584 https://reactome.org/PathwayBrowser/#/R-HSA-9634584 Estrogen receptor binds IGF1R and SHC1 in response to estrogen TAS Homo sapiens 50114 R-HSA-9709547 https://reactome.org/PathwayBrowser/#/R-HSA-9709547 ESTG binds ESR2:chaperone complex TAS Homo sapiens 50114 R-MMU-1254386 https://reactome.org/PathwayBrowser/#/R-MMU-1254386 ERBB4s80 forms a complex with estrogen receptor ESR1 IEA Mus musculus 50114 R-MMU-2316434 https://reactome.org/PathwayBrowser/#/R-MMU-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 50114 R-MMU-374207 https://reactome.org/PathwayBrowser/#/R-MMU-374207 G protein-coupled estrogen receptor 1 binds estrogen non-classically IEA Mus musculus 50114 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 50114 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 50114 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 50114 R-MMU-8931981 https://reactome.org/PathwayBrowser/#/R-MMU-8931981 RUNX1 binds ESR1 IEA Mus musculus 50114 R-MMU-8939201 https://reactome.org/PathwayBrowser/#/R-MMU-8939201 ESR dimerizes IEA Mus musculus 50114 R-MMU-8939204 https://reactome.org/PathwayBrowser/#/R-MMU-8939204 ESTG binds ESR1:chaperone complex IEA Mus musculus 50114 R-MMU-9011981 https://reactome.org/PathwayBrowser/#/R-MMU-9011981 EP300 is recruited to MYC and BCL2 genes IEA Mus musculus 50114 R-MMU-9011984 https://reactome.org/PathwayBrowser/#/R-MMU-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Mus musculus 50114 R-MMU-9011985 https://reactome.org/PathwayBrowser/#/R-MMU-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Mus musculus 50114 R-MMU-9012315 https://reactome.org/PathwayBrowser/#/R-MMU-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Mus musculus 50114 R-MMU-9012319 https://reactome.org/PathwayBrowser/#/R-MMU-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Mus musculus 50114 R-MMU-9018499 https://reactome.org/PathwayBrowser/#/R-MMU-9018499 ESR1:ESTG and EP300 are recruited to TFF3 promoter IEA Mus musculus 50114 R-MMU-9021170 https://reactome.org/PathwayBrowser/#/R-MMU-9021170 Estrogen stimulates dimerization of plasma membrane estrogen receptors IEA Mus musculus 50114 R-MMU-9021596 https://reactome.org/PathwayBrowser/#/R-MMU-9021596 Membrane estrogen receptors bind SRC IEA Mus musculus 50114 R-MMU-9021600 https://reactome.org/PathwayBrowser/#/R-MMU-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Mus musculus 50114 R-MMU-9021601 https://reactome.org/PathwayBrowser/#/R-MMU-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Mus musculus 50114 R-MMU-9021609 https://reactome.org/PathwayBrowser/#/R-MMU-9021609 ESR-associated SRC autophosphorylates IEA Mus musculus 50114 R-MMU-9021660 https://reactome.org/PathwayBrowser/#/R-MMU-9021660 PI3K binds membrane-associated estrogen receptors IEA Mus musculus 50114 R-MMU-9023840 https://reactome.org/PathwayBrowser/#/R-MMU-9023840 HATs and coactivators are recruited to the CTSD gene IEA Mus musculus 50114 R-MMU-9036301 https://reactome.org/PathwayBrowser/#/R-MMU-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Mus musculus 50114 R-MMU-9036307 https://reactome.org/PathwayBrowser/#/R-MMU-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Mus musculus 50114 R-MMU-9038052 https://reactome.org/PathwayBrowser/#/R-MMU-9038052 GREB1 binds ESR1:ESTG and co-activators IEA Mus musculus 50114 R-MMU-9038161 https://reactome.org/PathwayBrowser/#/R-MMU-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Mus musculus 50114 R-MMU-9038163 https://reactome.org/PathwayBrowser/#/R-MMU-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Mus musculus 50114 R-MMU-9624272 https://reactome.org/PathwayBrowser/#/R-MMU-9624272 MMPs cleave HB-EGF IEA Mus musculus 50114 R-MMU-9625814 https://reactome.org/PathwayBrowser/#/R-MMU-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Mus musculus 50114 R-MMU-9632182 https://reactome.org/PathwayBrowser/#/R-MMU-9632182 PRMT1 methylates ESRs IEA Mus musculus 50114 R-MMU-9632412 https://reactome.org/PathwayBrowser/#/R-MMU-9632412 PTK2 is recruited to methylated ESR1 IEA Mus musculus 50114 R-MMU-9633044 https://reactome.org/PathwayBrowser/#/R-MMU-9633044 ESR binds STRN IEA Mus musculus 50114 R-MMU-9634584 https://reactome.org/PathwayBrowser/#/R-MMU-9634584 Estrogen receptor binds IGF1R and SHC1 in response to estrogen IEA Mus musculus 50114 R-MMU-9709547 https://reactome.org/PathwayBrowser/#/R-MMU-9709547 ESTG binds ESR2:chaperone complex IEA Mus musculus 50114 R-PFA-9012319 https://reactome.org/PathwayBrowser/#/R-PFA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Plasmodium falciparum 50114 R-RNO-1254386 https://reactome.org/PathwayBrowser/#/R-RNO-1254386 ERBB4s80 forms a complex with estrogen receptor ESR1 IEA Rattus norvegicus 50114 R-RNO-2316434 https://reactome.org/PathwayBrowser/#/R-RNO-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 50114 R-RNO-374207 https://reactome.org/PathwayBrowser/#/R-RNO-374207 G protein-coupled estrogen receptor 1 binds estrogen non-classically IEA Rattus norvegicus 50114 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 50114 R-RNO-8931981 https://reactome.org/PathwayBrowser/#/R-RNO-8931981 RUNX1 binds ESR1 IEA Rattus norvegicus 50114 R-RNO-8939201 https://reactome.org/PathwayBrowser/#/R-RNO-8939201 ESR dimerizes IEA Rattus norvegicus 50114 R-RNO-8939204 https://reactome.org/PathwayBrowser/#/R-RNO-8939204 ESTG binds ESR1:chaperone complex IEA Rattus norvegicus 50114 R-RNO-9009371 https://reactome.org/PathwayBrowser/#/R-RNO-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Rattus norvegicus 50114 R-RNO-9011949 https://reactome.org/PathwayBrowser/#/R-RNO-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Rattus norvegicus 50114 R-RNO-9011952 https://reactome.org/PathwayBrowser/#/R-RNO-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Rattus norvegicus 50114 R-RNO-9011981 https://reactome.org/PathwayBrowser/#/R-RNO-9011981 EP300 is recruited to MYC and BCL2 genes IEA Rattus norvegicus 50114 R-RNO-9011984 https://reactome.org/PathwayBrowser/#/R-RNO-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Rattus norvegicus 50114 R-RNO-9011985 https://reactome.org/PathwayBrowser/#/R-RNO-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Rattus norvegicus 50114 R-RNO-9012000 https://reactome.org/PathwayBrowser/#/R-RNO-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Rattus norvegicus 50114 R-RNO-9012315 https://reactome.org/PathwayBrowser/#/R-RNO-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Rattus norvegicus 50114 R-RNO-9012319 https://reactome.org/PathwayBrowser/#/R-RNO-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Rattus norvegicus 50114 R-RNO-9018499 https://reactome.org/PathwayBrowser/#/R-RNO-9018499 ESR1:ESTG and EP300 are recruited to TFF3 promoter IEA Rattus norvegicus 50114 R-RNO-9021170 https://reactome.org/PathwayBrowser/#/R-RNO-9021170 Estrogen stimulates dimerization of plasma membrane estrogen receptors IEA Rattus norvegicus 50114 R-RNO-9021596 https://reactome.org/PathwayBrowser/#/R-RNO-9021596 Membrane estrogen receptors bind SRC IEA Rattus norvegicus 50114 R-RNO-9021609 https://reactome.org/PathwayBrowser/#/R-RNO-9021609 ESR-associated SRC autophosphorylates IEA Rattus norvegicus 50114 R-RNO-9021660 https://reactome.org/PathwayBrowser/#/R-RNO-9021660 PI3K binds membrane-associated estrogen receptors IEA Rattus norvegicus 50114 R-RNO-9038052 https://reactome.org/PathwayBrowser/#/R-RNO-9038052 GREB1 binds ESR1:ESTG and co-activators IEA Rattus norvegicus 50114 R-RNO-9038161 https://reactome.org/PathwayBrowser/#/R-RNO-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Rattus norvegicus 50114 R-RNO-9038163 https://reactome.org/PathwayBrowser/#/R-RNO-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Rattus norvegicus 50114 R-RNO-9624272 https://reactome.org/PathwayBrowser/#/R-RNO-9624272 MMPs cleave HB-EGF IEA Rattus norvegicus 50114 R-RNO-9625814 https://reactome.org/PathwayBrowser/#/R-RNO-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Rattus norvegicus 50114 R-RNO-9632182 https://reactome.org/PathwayBrowser/#/R-RNO-9632182 PRMT1 methylates ESRs IEA Rattus norvegicus 50114 R-RNO-9632412 https://reactome.org/PathwayBrowser/#/R-RNO-9632412 PTK2 is recruited to methylated ESR1 IEA Rattus norvegicus 50114 R-RNO-9633044 https://reactome.org/PathwayBrowser/#/R-RNO-9633044 ESR binds STRN IEA Rattus norvegicus 50114 R-RNO-9634584 https://reactome.org/PathwayBrowser/#/R-RNO-9634584 Estrogen receptor binds IGF1R and SHC1 in response to estrogen IEA Rattus norvegicus 50114 R-RNO-9709547 https://reactome.org/PathwayBrowser/#/R-RNO-9709547 ESTG binds ESR2:chaperone complex IEA Rattus norvegicus 50114 R-SCE-9011949 https://reactome.org/PathwayBrowser/#/R-SCE-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Saccharomyces cerevisiae 50114 R-SCE-9011984 https://reactome.org/PathwayBrowser/#/R-SCE-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Saccharomyces cerevisiae 50114 R-SCE-9011985 https://reactome.org/PathwayBrowser/#/R-SCE-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Saccharomyces cerevisiae 50114 R-SCE-9012319 https://reactome.org/PathwayBrowser/#/R-SCE-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Saccharomyces cerevisiae 50114 R-SPO-9011984 https://reactome.org/PathwayBrowser/#/R-SPO-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Schizosaccharomyces pombe 50114 R-SPO-9011985 https://reactome.org/PathwayBrowser/#/R-SPO-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Schizosaccharomyces pombe 50114 R-SPO-9012319 https://reactome.org/PathwayBrowser/#/R-SPO-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Schizosaccharomyces pombe 50114 R-SSC-1254386 https://reactome.org/PathwayBrowser/#/R-SSC-1254386 ERBB4s80 forms a complex with estrogen receptor ESR1 IEA Sus scrofa 50114 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 50114 R-SSC-374207 https://reactome.org/PathwayBrowser/#/R-SSC-374207 G protein-coupled estrogen receptor 1 binds estrogen non-classically IEA Sus scrofa 50114 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 50114 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 50114 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 50114 R-SSC-8931981 https://reactome.org/PathwayBrowser/#/R-SSC-8931981 RUNX1 binds ESR1 IEA Sus scrofa 50114 R-SSC-8939201 https://reactome.org/PathwayBrowser/#/R-SSC-8939201 ESR dimerizes IEA Sus scrofa 50114 R-SSC-8939204 https://reactome.org/PathwayBrowser/#/R-SSC-8939204 ESTG binds ESR1:chaperone complex IEA Sus scrofa 50114 R-SSC-9009371 https://reactome.org/PathwayBrowser/#/R-SSC-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Sus scrofa 50114 R-SSC-9011949 https://reactome.org/PathwayBrowser/#/R-SSC-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Sus scrofa 50114 R-SSC-9011952 https://reactome.org/PathwayBrowser/#/R-SSC-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Sus scrofa 50114 R-SSC-9011981 https://reactome.org/PathwayBrowser/#/R-SSC-9011981 EP300 is recruited to MYC and BCL2 genes IEA Sus scrofa 50114 R-SSC-9011983 https://reactome.org/PathwayBrowser/#/R-SSC-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Sus scrofa 50114 R-SSC-9011984 https://reactome.org/PathwayBrowser/#/R-SSC-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Sus scrofa 50114 R-SSC-9011985 https://reactome.org/PathwayBrowser/#/R-SSC-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Sus scrofa 50114 R-SSC-9012000 https://reactome.org/PathwayBrowser/#/R-SSC-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Sus scrofa 50114 R-SSC-9012315 https://reactome.org/PathwayBrowser/#/R-SSC-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Sus scrofa 50114 R-SSC-9012319 https://reactome.org/PathwayBrowser/#/R-SSC-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Sus scrofa 50114 R-SSC-9018499 https://reactome.org/PathwayBrowser/#/R-SSC-9018499 ESR1:ESTG and EP300 are recruited to TFF3 promoter IEA Sus scrofa 50114 R-SSC-9021170 https://reactome.org/PathwayBrowser/#/R-SSC-9021170 Estrogen stimulates dimerization of plasma membrane estrogen receptors IEA Sus scrofa 50114 R-SSC-9021596 https://reactome.org/PathwayBrowser/#/R-SSC-9021596 Membrane estrogen receptors bind SRC IEA Sus scrofa 50114 R-SSC-9021600 https://reactome.org/PathwayBrowser/#/R-SSC-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Sus scrofa 50114 R-SSC-9021601 https://reactome.org/PathwayBrowser/#/R-SSC-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Sus scrofa 50114 R-SSC-9021609 https://reactome.org/PathwayBrowser/#/R-SSC-9021609 ESR-associated SRC autophosphorylates IEA Sus scrofa 50114 R-SSC-9021660 https://reactome.org/PathwayBrowser/#/R-SSC-9021660 PI3K binds membrane-associated estrogen receptors IEA Sus scrofa 50114 R-SSC-9023840 https://reactome.org/PathwayBrowser/#/R-SSC-9023840 HATs and coactivators are recruited to the CTSD gene IEA Sus scrofa 50114 R-SSC-9036301 https://reactome.org/PathwayBrowser/#/R-SSC-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Sus scrofa 50114 R-SSC-9036307 https://reactome.org/PathwayBrowser/#/R-SSC-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Sus scrofa 50114 R-SSC-9038052 https://reactome.org/PathwayBrowser/#/R-SSC-9038052 GREB1 binds ESR1:ESTG and co-activators IEA Sus scrofa 50114 R-SSC-9038161 https://reactome.org/PathwayBrowser/#/R-SSC-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Sus scrofa 50114 R-SSC-9038163 https://reactome.org/PathwayBrowser/#/R-SSC-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Sus scrofa 50114 R-SSC-9624272 https://reactome.org/PathwayBrowser/#/R-SSC-9624272 MMPs cleave HB-EGF IEA Sus scrofa 50114 R-SSC-9625814 https://reactome.org/PathwayBrowser/#/R-SSC-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Sus scrofa 50114 R-SSC-9632182 https://reactome.org/PathwayBrowser/#/R-SSC-9632182 PRMT1 methylates ESRs IEA Sus scrofa 50114 R-SSC-9633044 https://reactome.org/PathwayBrowser/#/R-SSC-9633044 ESR binds STRN IEA Sus scrofa 50114 R-SSC-9634584 https://reactome.org/PathwayBrowser/#/R-SSC-9634584 Estrogen receptor binds IGF1R and SHC1 in response to estrogen IEA Sus scrofa 50114 R-SSC-9709547 https://reactome.org/PathwayBrowser/#/R-SSC-9709547 ESTG binds ESR2:chaperone complex IEA Sus scrofa 50114 R-XTR-1254386 https://reactome.org/PathwayBrowser/#/R-XTR-1254386 ERBB4s80 forms a complex with estrogen receptor ESR1 IEA Xenopus tropicalis 50114 R-XTR-2316434 https://reactome.org/PathwayBrowser/#/R-XTR-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 50114 R-XTR-374207 https://reactome.org/PathwayBrowser/#/R-XTR-374207 G protein-coupled estrogen receptor 1 binds estrogen non-classically IEA Xenopus tropicalis 50114 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 50114 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 50114 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 50114 R-XTR-8939201 https://reactome.org/PathwayBrowser/#/R-XTR-8939201 ESR dimerizes IEA Xenopus tropicalis 50114 R-XTR-8939204 https://reactome.org/PathwayBrowser/#/R-XTR-8939204 ESTG binds ESR1:chaperone complex IEA Xenopus tropicalis 50114 R-XTR-9011949 https://reactome.org/PathwayBrowser/#/R-XTR-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Xenopus tropicalis 50114 R-XTR-9011952 https://reactome.org/PathwayBrowser/#/R-XTR-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Xenopus tropicalis 50114 R-XTR-9011981 https://reactome.org/PathwayBrowser/#/R-XTR-9011981 EP300 is recruited to MYC and BCL2 genes IEA Xenopus tropicalis 50114 R-XTR-9011983 https://reactome.org/PathwayBrowser/#/R-XTR-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Xenopus tropicalis 50114 R-XTR-9011984 https://reactome.org/PathwayBrowser/#/R-XTR-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Xenopus tropicalis 50114 R-XTR-9011985 https://reactome.org/PathwayBrowser/#/R-XTR-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Xenopus tropicalis 50114 R-XTR-9012000 https://reactome.org/PathwayBrowser/#/R-XTR-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Xenopus tropicalis 50114 R-XTR-9012319 https://reactome.org/PathwayBrowser/#/R-XTR-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Xenopus tropicalis 50114 R-XTR-9021170 https://reactome.org/PathwayBrowser/#/R-XTR-9021170 Estrogen stimulates dimerization of plasma membrane estrogen receptors IEA Xenopus tropicalis 50114 R-XTR-9021600 https://reactome.org/PathwayBrowser/#/R-XTR-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Xenopus tropicalis 50114 R-XTR-9021601 https://reactome.org/PathwayBrowser/#/R-XTR-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Xenopus tropicalis 50114 R-XTR-9023840 https://reactome.org/PathwayBrowser/#/R-XTR-9023840 HATs and coactivators are recruited to the CTSD gene IEA Xenopus tropicalis 50114 R-XTR-9036301 https://reactome.org/PathwayBrowser/#/R-XTR-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Xenopus tropicalis 50114 R-XTR-9036307 https://reactome.org/PathwayBrowser/#/R-XTR-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Xenopus tropicalis 50114 R-XTR-9624272 https://reactome.org/PathwayBrowser/#/R-XTR-9624272 MMPs cleave HB-EGF IEA Xenopus tropicalis 50114 R-XTR-9632182 https://reactome.org/PathwayBrowser/#/R-XTR-9632182 PRMT1 methylates ESRs IEA Xenopus tropicalis 50114 R-XTR-9633044 https://reactome.org/PathwayBrowser/#/R-XTR-9633044 ESR binds STRN IEA Xenopus tropicalis 50114 R-XTR-9709547 https://reactome.org/PathwayBrowser/#/R-XTR-9709547 ESTG binds ESR2:chaperone complex IEA Xenopus tropicalis 50122 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 50122 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 50122 R-BTA-400434 https://reactome.org/PathwayBrowser/#/R-BTA-400434 FFAR1 binds fatty acids IEA Bos taurus 50122 R-BTA-400509 https://reactome.org/PathwayBrowser/#/R-BTA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Bos taurus 50122 R-BTA-416530 https://reactome.org/PathwayBrowser/#/R-BTA-416530 FFAR1:FFAR1 ligands activate Gq IEA Bos taurus 50122 R-BTA-444202 https://reactome.org/PathwayBrowser/#/R-BTA-444202 Receptor FFAR1 binds free fatty acids IEA Bos taurus 50122 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 50122 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 50122 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 50122 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 50122 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 50122 R-CFA-400434 https://reactome.org/PathwayBrowser/#/R-CFA-400434 FFAR1 binds fatty acids IEA Canis familiaris 50122 R-CFA-400509 https://reactome.org/PathwayBrowser/#/R-CFA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Canis familiaris 50122 R-CFA-416530 https://reactome.org/PathwayBrowser/#/R-CFA-416530 FFAR1:FFAR1 ligands activate Gq IEA Canis familiaris 50122 R-CFA-444202 https://reactome.org/PathwayBrowser/#/R-CFA-444202 Receptor FFAR1 binds free fatty acids IEA Canis familiaris 50122 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 50122 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 50122 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 50122 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 50122 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 50122 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 50122 R-HSA-400434 https://reactome.org/PathwayBrowser/#/R-HSA-400434 FFAR1 binds fatty acids TAS Homo sapiens 50122 R-HSA-400509 https://reactome.org/PathwayBrowser/#/R-HSA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells TAS Homo sapiens 50122 R-HSA-416530 https://reactome.org/PathwayBrowser/#/R-HSA-416530 FFAR1:FFAR1 ligands activate Gq TAS Homo sapiens 50122 R-HSA-444202 https://reactome.org/PathwayBrowser/#/R-HSA-444202 Receptor FFAR1 binds free fatty acids TAS Homo sapiens 50122 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 50122 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 50122 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 50122 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 50122 R-MMU-400434 https://reactome.org/PathwayBrowser/#/R-MMU-400434 FFAR1 binds fatty acids IEA Mus musculus 50122 R-MMU-400509 https://reactome.org/PathwayBrowser/#/R-MMU-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Mus musculus 50122 R-MMU-416530 https://reactome.org/PathwayBrowser/#/R-MMU-416530 FFAR1:FFAR1 ligands activate Gq IEA Mus musculus 50122 R-MMU-444202 https://reactome.org/PathwayBrowser/#/R-MMU-444202 Receptor FFAR1 binds free fatty acids IEA Mus musculus 50122 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 50122 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 50122 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 50122 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 50122 R-RNO-400434 https://reactome.org/PathwayBrowser/#/R-RNO-400434 FFAR1 binds fatty acids IEA Rattus norvegicus 50122 R-RNO-400509 https://reactome.org/PathwayBrowser/#/R-RNO-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Rattus norvegicus 50122 R-RNO-416530 https://reactome.org/PathwayBrowser/#/R-RNO-416530 FFAR1:FFAR1 ligands activate Gq IEA Rattus norvegicus 50122 R-RNO-444202 https://reactome.org/PathwayBrowser/#/R-RNO-444202 Receptor FFAR1 binds free fatty acids IEA Rattus norvegicus 50122 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 50122 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 50131 R-HSA-9710480 https://reactome.org/PathwayBrowser/#/R-HSA-9710480 Decitabine triphosphate incorporates into DNA TAS Homo sapiens 50131 R-HSA-9710490 https://reactome.org/PathwayBrowser/#/R-HSA-9710490 The GSDME gene promoter is hypermethylated TAS Homo sapiens 50157 R-BTA-141186 https://reactome.org/PathwayBrowser/#/R-BTA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Bos taurus 50157 R-BTA-380608 https://reactome.org/PathwayBrowser/#/R-BTA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Bos taurus 50157 R-CEL-380608 https://reactome.org/PathwayBrowser/#/R-CEL-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Caenorhabditis elegans 50157 R-CFA-141186 https://reactome.org/PathwayBrowser/#/R-CFA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Canis familiaris 50157 R-CFA-380608 https://reactome.org/PathwayBrowser/#/R-CFA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Canis familiaris 50157 R-DDI-141186 https://reactome.org/PathwayBrowser/#/R-DDI-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Dictyostelium discoideum 50157 R-DDI-380608 https://reactome.org/PathwayBrowser/#/R-DDI-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Dictyostelium discoideum 50157 R-DME-380608 https://reactome.org/PathwayBrowser/#/R-DME-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Drosophila melanogaster 50157 R-DRE-380608 https://reactome.org/PathwayBrowser/#/R-DRE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Danio rerio 50157 R-GGA-141186 https://reactome.org/PathwayBrowser/#/R-GGA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Gallus gallus 50157 R-GGA-380608 https://reactome.org/PathwayBrowser/#/R-GGA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Gallus gallus 50157 R-HSA-141186 https://reactome.org/PathwayBrowser/#/R-HSA-141186 MAOA:FAD oxidatively deaminates of 5HT TAS Homo sapiens 50157 R-HSA-380608 https://reactome.org/PathwayBrowser/#/R-HSA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid TAS Homo sapiens 50157 R-MMU-141186 https://reactome.org/PathwayBrowser/#/R-MMU-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Mus musculus 50157 R-MMU-380608 https://reactome.org/PathwayBrowser/#/R-MMU-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Mus musculus 50157 R-RNO-141186 https://reactome.org/PathwayBrowser/#/R-RNO-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Rattus norvegicus 50157 R-RNO-380608 https://reactome.org/PathwayBrowser/#/R-RNO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Rattus norvegicus 50157 R-SCE-380608 https://reactome.org/PathwayBrowser/#/R-SCE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Saccharomyces cerevisiae 50157 R-SPO-380608 https://reactome.org/PathwayBrowser/#/R-SPO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Schizosaccharomyces pombe 50157 R-SSC-141186 https://reactome.org/PathwayBrowser/#/R-SSC-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Sus scrofa 50157 R-SSC-380608 https://reactome.org/PathwayBrowser/#/R-SSC-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Sus scrofa 50157 R-XTR-380608 https://reactome.org/PathwayBrowser/#/R-XTR-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Xenopus tropicalis 50172 R-BTA-9009817 https://reactome.org/PathwayBrowser/#/R-BTA-9009817 Acitretin binds to RAR:RXR IEA Bos taurus 50172 R-CEL-9009817 https://reactome.org/PathwayBrowser/#/R-CEL-9009817 Acitretin binds to RAR:RXR IEA Caenorhabditis elegans 50172 R-CFA-9009817 https://reactome.org/PathwayBrowser/#/R-CFA-9009817 Acitretin binds to RAR:RXR IEA Canis familiaris 50172 R-DME-9009817 https://reactome.org/PathwayBrowser/#/R-DME-9009817 Acitretin binds to RAR:RXR IEA Drosophila melanogaster 50172 R-DRE-9009817 https://reactome.org/PathwayBrowser/#/R-DRE-9009817 Acitretin binds to RAR:RXR IEA Danio rerio 50172 R-GGA-9009817 https://reactome.org/PathwayBrowser/#/R-GGA-9009817 Acitretin binds to RAR:RXR IEA Gallus gallus 50172 R-HSA-9009817 https://reactome.org/PathwayBrowser/#/R-HSA-9009817 Acitretin binds to RAR:RXR TAS Homo sapiens 50172 R-MMU-9009817 https://reactome.org/PathwayBrowser/#/R-MMU-9009817 Acitretin binds to RAR:RXR IEA Mus musculus 50172 R-RNO-9009817 https://reactome.org/PathwayBrowser/#/R-RNO-9009817 Acitretin binds to RAR:RXR IEA Rattus norvegicus 50172 R-SSC-9009817 https://reactome.org/PathwayBrowser/#/R-SSC-9009817 Acitretin binds to RAR:RXR IEA Sus scrofa 50277 R-BTA-2530501 https://reactome.org/PathwayBrowser/#/R-BTA-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Bos taurus 50277 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 50277 R-CEL-2530501 https://reactome.org/PathwayBrowser/#/R-CEL-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Caenorhabditis elegans 50277 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 50277 R-DME-2530501 https://reactome.org/PathwayBrowser/#/R-DME-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Drosophila melanogaster 50277 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 50277 R-DRE-2530501 https://reactome.org/PathwayBrowser/#/R-DRE-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Danio rerio 50277 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 50277 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 50277 R-HSA-2530501 https://reactome.org/PathwayBrowser/#/R-HSA-2530501 FNTA:FNTB transfers FARN to GNGT1 TAS Homo sapiens 50277 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 50277 R-MMU-2530501 https://reactome.org/PathwayBrowser/#/R-MMU-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Mus musculus 50277 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 50277 R-RNO-2530501 https://reactome.org/PathwayBrowser/#/R-RNO-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Rattus norvegicus 50277 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 50277 R-XTR-2530501 https://reactome.org/PathwayBrowser/#/R-XTR-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Xenopus tropicalis 50385 R-GGA-421508 https://reactome.org/PathwayBrowser/#/R-GGA-421508 Synthesis of ALAS1 nascent polypeptide TAS Gallus gallus 50438 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 50438 R-BTA-9026967 https://reactome.org/PathwayBrowser/#/R-BTA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Bos taurus 50438 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 50438 R-CFA-9026967 https://reactome.org/PathwayBrowser/#/R-CFA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Canis familiaris 50438 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 50438 R-DME-9026967 https://reactome.org/PathwayBrowser/#/R-DME-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Drosophila melanogaster 50438 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 50438 R-HSA-9026967 https://reactome.org/PathwayBrowser/#/R-HSA-9026967 VKORC1 inhibitors binds VKORC1 dimer TAS Homo sapiens 50438 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 50438 R-MMU-9026967 https://reactome.org/PathwayBrowser/#/R-MMU-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Mus musculus 50438 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 50438 R-RNO-9026967 https://reactome.org/PathwayBrowser/#/R-RNO-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Rattus norvegicus 50438 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 50438 R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa 50438 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 50438 R-XTR-9026967 https://reactome.org/PathwayBrowser/#/R-XTR-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Xenopus tropicalis 50570 R-BTA-548831 https://reactome.org/PathwayBrowser/#/R-BTA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Bos taurus 50570 R-CEL-548831 https://reactome.org/PathwayBrowser/#/R-CEL-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Caenorhabditis elegans 50570 R-CFA-548831 https://reactome.org/PathwayBrowser/#/R-CFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Canis familiaris 50570 R-DDI-548831 https://reactome.org/PathwayBrowser/#/R-DDI-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Dictyostelium discoideum 50570 R-DME-548831 https://reactome.org/PathwayBrowser/#/R-DME-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Drosophila melanogaster 50570 R-GGA-548831 https://reactome.org/PathwayBrowser/#/R-GGA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Gallus gallus 50570 R-HSA-548831 https://reactome.org/PathwayBrowser/#/R-HSA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA TAS Homo sapiens 50570 R-MMU-548831 https://reactome.org/PathwayBrowser/#/R-MMU-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Mus musculus 50570 R-PFA-548831 https://reactome.org/PathwayBrowser/#/R-PFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Plasmodium falciparum 50570 R-RNO-548831 https://reactome.org/PathwayBrowser/#/R-RNO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Rattus norvegicus 50570 R-SCE-548831 https://reactome.org/PathwayBrowser/#/R-SCE-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Saccharomyces cerevisiae 50570 R-SPO-548831 https://reactome.org/PathwayBrowser/#/R-SPO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Schizosaccharomyces pombe 50570 R-SSC-548831 https://reactome.org/PathwayBrowser/#/R-SSC-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Sus scrofa 50570 R-XTR-548831 https://reactome.org/PathwayBrowser/#/R-XTR-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Xenopus tropicalis 50583 R-BTA-548818 https://reactome.org/PathwayBrowser/#/R-BTA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Bos taurus 50583 R-CEL-548818 https://reactome.org/PathwayBrowser/#/R-CEL-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Caenorhabditis elegans 50583 R-CFA-548818 https://reactome.org/PathwayBrowser/#/R-CFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Canis familiaris 50583 R-DDI-548818 https://reactome.org/PathwayBrowser/#/R-DDI-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Dictyostelium discoideum 50583 R-DME-548818 https://reactome.org/PathwayBrowser/#/R-DME-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Drosophila melanogaster 50583 R-DRE-548818 https://reactome.org/PathwayBrowser/#/R-DRE-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Danio rerio 50583 R-GGA-548818 https://reactome.org/PathwayBrowser/#/R-GGA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Gallus gallus 50583 R-HSA-548818 https://reactome.org/PathwayBrowser/#/R-HSA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA TAS Homo sapiens 50583 R-MMU-548818 https://reactome.org/PathwayBrowser/#/R-MMU-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Mus musculus 50583 R-PFA-548818 https://reactome.org/PathwayBrowser/#/R-PFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Plasmodium falciparum 50583 R-RNO-548818 https://reactome.org/PathwayBrowser/#/R-RNO-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Rattus norvegicus 50583 R-SSC-548818 https://reactome.org/PathwayBrowser/#/R-SSC-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Sus scrofa 50583 R-XTR-548818 https://reactome.org/PathwayBrowser/#/R-XTR-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Xenopus tropicalis 50593 R-BTA-194642 https://reactome.org/PathwayBrowser/#/R-BTA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Bos taurus 50593 R-BTA-194689 https://reactome.org/PathwayBrowser/#/R-BTA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Bos taurus 50593 R-CEL-194642 https://reactome.org/PathwayBrowser/#/R-CEL-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Caenorhabditis elegans 50593 R-CFA-194642 https://reactome.org/PathwayBrowser/#/R-CFA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Canis familiaris 50593 R-CFA-194689 https://reactome.org/PathwayBrowser/#/R-CFA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 50593 R-DDI-194642 https://reactome.org/PathwayBrowser/#/R-DDI-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Dictyostelium discoideum 50593 R-DRE-194642 https://reactome.org/PathwayBrowser/#/R-DRE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Danio rerio 50593 R-DRE-194689 https://reactome.org/PathwayBrowser/#/R-DRE-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Danio rerio 50593 R-GGA-194642 https://reactome.org/PathwayBrowser/#/R-GGA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Gallus gallus 50593 R-GGA-194689 https://reactome.org/PathwayBrowser/#/R-GGA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 50593 R-HSA-194642 https://reactome.org/PathwayBrowser/#/R-HSA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one TAS Homo sapiens 50593 R-HSA-194689 https://reactome.org/PathwayBrowser/#/R-HSA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 50593 R-MMU-194642 https://reactome.org/PathwayBrowser/#/R-MMU-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Mus musculus 50593 R-MMU-194689 https://reactome.org/PathwayBrowser/#/R-MMU-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Mus musculus 50593 R-RNO-194642 https://reactome.org/PathwayBrowser/#/R-RNO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Rattus norvegicus 50593 R-RNO-194689 https://reactome.org/PathwayBrowser/#/R-RNO-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 50593 R-SCE-194642 https://reactome.org/PathwayBrowser/#/R-SCE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Saccharomyces cerevisiae 50593 R-SPO-194642 https://reactome.org/PathwayBrowser/#/R-SPO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Schizosaccharomyces pombe 50593 R-SSC-194642 https://reactome.org/PathwayBrowser/#/R-SSC-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Sus scrofa 50593 R-SSC-194689 https://reactome.org/PathwayBrowser/#/R-SSC-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 50648 R-BTA-211923 https://reactome.org/PathwayBrowser/#/R-BTA-211923 CYP26C1 4-hydroxylates 9cRA IEA Bos taurus 50648 R-BTA-5246478 https://reactome.org/PathwayBrowser/#/R-BTA-5246478 APOM binds retinoids IEA Bos taurus 50648 R-BTA-5696101 https://reactome.org/PathwayBrowser/#/R-BTA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Bos taurus 50648 R-CEL-5696101 https://reactome.org/PathwayBrowser/#/R-CEL-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Caenorhabditis elegans 50648 R-CFA-211923 https://reactome.org/PathwayBrowser/#/R-CFA-211923 CYP26C1 4-hydroxylates 9cRA IEA Canis familiaris 50648 R-CFA-5246478 https://reactome.org/PathwayBrowser/#/R-CFA-5246478 APOM binds retinoids IEA Canis familiaris 50648 R-CFA-5696101 https://reactome.org/PathwayBrowser/#/R-CFA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Canis familiaris 50648 R-DDI-5696101 https://reactome.org/PathwayBrowser/#/R-DDI-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Dictyostelium discoideum 50648 R-DRE-211923 https://reactome.org/PathwayBrowser/#/R-DRE-211923 CYP26C1 4-hydroxylates 9cRA IEA Danio rerio 50648 R-DRE-5696101 https://reactome.org/PathwayBrowser/#/R-DRE-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Danio rerio 50648 R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus 50648 R-GGA-5696101 https://reactome.org/PathwayBrowser/#/R-GGA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Gallus gallus 50648 R-HSA-211923 https://reactome.org/PathwayBrowser/#/R-HSA-211923 CYP26C1 4-hydroxylates 9cRA TAS Homo sapiens 50648 R-HSA-5246478 https://reactome.org/PathwayBrowser/#/R-HSA-5246478 APOM binds retinoids TAS Homo sapiens 50648 R-HSA-5602050 https://reactome.org/PathwayBrowser/#/R-HSA-5602050 Defective CYP26C1 does not 4-hydroxylate 9cRA TAS Homo sapiens 50648 R-HSA-5696101 https://reactome.org/PathwayBrowser/#/R-HSA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA TAS Homo sapiens 50648 R-HSA-9844415 https://reactome.org/PathwayBrowser/#/R-HSA-9844415 PRDM16 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 IEA Homo sapiens 50648 R-HSA-9844440 https://reactome.org/PathwayBrowser/#/R-HSA-9844440 PPARG binds EBF2-bound gene loci IEA Homo sapiens 50648 R-HSA-9844536 https://reactome.org/PathwayBrowser/#/R-HSA-9844536 PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 50648 R-HSA-9844549 https://reactome.org/PathwayBrowser/#/R-HSA-9844549 UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 50648 R-HSA-9844600 https://reactome.org/PathwayBrowser/#/R-HSA-9844600 CIDEA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 50648 R-HSA-9844822 https://reactome.org/PathwayBrowser/#/R-HSA-9844822 PPARGC1A gene expression is stimulated by EBF2 IEA Homo sapiens 50648 R-MMU-211923 https://reactome.org/PathwayBrowser/#/R-MMU-211923 CYP26C1 4-hydroxylates 9cRA IEA Mus musculus 50648 R-MMU-5246478 https://reactome.org/PathwayBrowser/#/R-MMU-5246478 APOM binds retinoids IEA Mus musculus 50648 R-MMU-5696101 https://reactome.org/PathwayBrowser/#/R-MMU-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Mus musculus 50648 R-MMU-9844541 https://reactome.org/PathwayBrowser/#/R-MMU-9844541 Ppara gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 50648 R-MMU-9844554 https://reactome.org/PathwayBrowser/#/R-MMU-9844554 Ucp1 gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 50648 R-MMU-9844626 https://reactome.org/PathwayBrowser/#/R-MMU-9844626 Cidea gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 50648 R-MMU-9844655 https://reactome.org/PathwayBrowser/#/R-MMU-9844655 Dio2 gene expression is stimulated by Ebf2 and repressed by Znf423 and NuRD TAS Mus musculus 50648 R-MMU-9844700 https://reactome.org/PathwayBrowser/#/R-MMU-9844700 Pparg binds Ebf2-bound gene loci TAS Mus musculus 50648 R-MMU-9844775 https://reactome.org/PathwayBrowser/#/R-MMU-9844775 Prdm16 gene expression is stimulated by Ebf2 and Pparg and inhibited by Znf423 TAS Mus musculus 50648 R-MMU-9844841 https://reactome.org/PathwayBrowser/#/R-MMU-9844841 Ppargc1a gene expression is positively regulated by Ebf2 and Pparg TAS Mus musculus 50648 R-RNO-211923 https://reactome.org/PathwayBrowser/#/R-RNO-211923 CYP26C1 4-hydroxylates 9cRA IEA Rattus norvegicus 50648 R-RNO-5246478 https://reactome.org/PathwayBrowser/#/R-RNO-5246478 APOM binds retinoids IEA Rattus norvegicus 50648 R-RNO-5696101 https://reactome.org/PathwayBrowser/#/R-RNO-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Rattus norvegicus 50648 R-SSC-211923 https://reactome.org/PathwayBrowser/#/R-SSC-211923 CYP26C1 4-hydroxylates 9cRA IEA Sus scrofa 50648 R-SSC-5246478 https://reactome.org/PathwayBrowser/#/R-SSC-5246478 APOM binds retinoids IEA Sus scrofa 50648 R-SSC-5696101 https://reactome.org/PathwayBrowser/#/R-SSC-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Sus scrofa 50648 R-XTR-211923 https://reactome.org/PathwayBrowser/#/R-XTR-211923 CYP26C1 4-hydroxylates 9cRA IEA Xenopus tropicalis 50648 R-XTR-5246478 https://reactome.org/PathwayBrowser/#/R-XTR-5246478 APOM binds retinoids IEA Xenopus tropicalis 50648 R-XTR-5696101 https://reactome.org/PathwayBrowser/#/R-XTR-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Xenopus tropicalis 50659 R-BTA-9613570 https://reactome.org/PathwayBrowser/#/R-BTA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Bos taurus 50659 R-CEL-9613570 https://reactome.org/PathwayBrowser/#/R-CEL-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Caenorhabditis elegans 50659 R-CFA-9613570 https://reactome.org/PathwayBrowser/#/R-CFA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Canis familiaris 50659 R-DME-9613570 https://reactome.org/PathwayBrowser/#/R-DME-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Drosophila melanogaster 50659 R-GGA-9613570 https://reactome.org/PathwayBrowser/#/R-GGA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Gallus gallus 50659 R-HSA-9613570 https://reactome.org/PathwayBrowser/#/R-HSA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers TAS Homo sapiens 50659 R-MMU-9613570 https://reactome.org/PathwayBrowser/#/R-MMU-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Mus musculus 50659 R-PFA-9613570 https://reactome.org/PathwayBrowser/#/R-PFA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Plasmodium falciparum 50659 R-RNO-9613570 https://reactome.org/PathwayBrowser/#/R-RNO-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Rattus norvegicus 50659 R-SSC-9613570 https://reactome.org/PathwayBrowser/#/R-SSC-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Sus scrofa 50659 R-XTR-9613570 https://reactome.org/PathwayBrowser/#/R-XTR-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Xenopus tropicalis 50667 R-BTA-9748951 https://reactome.org/PathwayBrowser/#/R-BTA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Bos taurus 50667 R-BTA-9748983 https://reactome.org/PathwayBrowser/#/R-BTA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Bos taurus 50667 R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 50667 R-BTA-9748996 https://reactome.org/PathwayBrowser/#/R-BTA-9748996 GST dimers cleave AZA to 6MP IEA Bos taurus 50667 R-BTA-9751024 https://reactome.org/PathwayBrowser/#/R-BTA-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Bos taurus 50667 R-BTA-9751037 https://reactome.org/PathwayBrowser/#/R-BTA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Bos taurus 50667 R-CEL-9748951 https://reactome.org/PathwayBrowser/#/R-CEL-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Caenorhabditis elegans 50667 R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 50667 R-CEL-9751024 https://reactome.org/PathwayBrowser/#/R-CEL-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Caenorhabditis elegans 50667 R-CEL-9751037 https://reactome.org/PathwayBrowser/#/R-CEL-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 50667 R-CFA-9748951 https://reactome.org/PathwayBrowser/#/R-CFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Canis familiaris 50667 R-CFA-9748983 https://reactome.org/PathwayBrowser/#/R-CFA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Canis familiaris 50667 R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 50667 R-CFA-9748996 https://reactome.org/PathwayBrowser/#/R-CFA-9748996 GST dimers cleave AZA to 6MP IEA Canis familiaris 50667 R-CFA-9751024 https://reactome.org/PathwayBrowser/#/R-CFA-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Canis familiaris 50667 R-CFA-9751037 https://reactome.org/PathwayBrowser/#/R-CFA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Canis familiaris 50667 R-DDI-9748951 https://reactome.org/PathwayBrowser/#/R-DDI-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Dictyostelium discoideum 50667 R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 50667 R-DDI-9748996 https://reactome.org/PathwayBrowser/#/R-DDI-9748996 GST dimers cleave AZA to 6MP IEA Dictyostelium discoideum 50667 R-DDI-9751024 https://reactome.org/PathwayBrowser/#/R-DDI-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Dictyostelium discoideum 50667 R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 50667 R-DME-9751024 https://reactome.org/PathwayBrowser/#/R-DME-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Drosophila melanogaster 50667 R-DME-9751037 https://reactome.org/PathwayBrowser/#/R-DME-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 50667 R-DRE-9748951 https://reactome.org/PathwayBrowser/#/R-DRE-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Danio rerio 50667 R-DRE-9748983 https://reactome.org/PathwayBrowser/#/R-DRE-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Danio rerio 50667 R-DRE-9748996 https://reactome.org/PathwayBrowser/#/R-DRE-9748996 GST dimers cleave AZA to 6MP IEA Danio rerio 50667 R-DRE-9751024 https://reactome.org/PathwayBrowser/#/R-DRE-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Danio rerio 50667 R-GGA-9748951 https://reactome.org/PathwayBrowser/#/R-GGA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Gallus gallus 50667 R-GGA-9748983 https://reactome.org/PathwayBrowser/#/R-GGA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Gallus gallus 50667 R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 50667 R-GGA-9748996 https://reactome.org/PathwayBrowser/#/R-GGA-9748996 GST dimers cleave AZA to 6MP IEA Gallus gallus 50667 R-GGA-9751037 https://reactome.org/PathwayBrowser/#/R-GGA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Gallus gallus 50667 R-HSA-9748951 https://reactome.org/PathwayBrowser/#/R-HSA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP TAS Homo sapiens 50667 R-HSA-9748983 https://reactome.org/PathwayBrowser/#/R-HSA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP TAS Homo sapiens 50667 R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 50667 R-HSA-9748996 https://reactome.org/PathwayBrowser/#/R-HSA-9748996 GST dimers cleave AZA to 6MP TAS Homo sapiens 50667 R-HSA-9751024 https://reactome.org/PathwayBrowser/#/R-HSA-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol TAS Homo sapiens 50667 R-HSA-9751037 https://reactome.org/PathwayBrowser/#/R-HSA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol TAS Homo sapiens 50667 R-MMU-9748951 https://reactome.org/PathwayBrowser/#/R-MMU-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Mus musculus 50667 R-MMU-9748983 https://reactome.org/PathwayBrowser/#/R-MMU-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Mus musculus 50667 R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 50667 R-MMU-9748996 https://reactome.org/PathwayBrowser/#/R-MMU-9748996 GST dimers cleave AZA to 6MP IEA Mus musculus 50667 R-MMU-9751024 https://reactome.org/PathwayBrowser/#/R-MMU-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Mus musculus 50667 R-MMU-9751037 https://reactome.org/PathwayBrowser/#/R-MMU-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Mus musculus 50667 R-PFA-9748951 https://reactome.org/PathwayBrowser/#/R-PFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Plasmodium falciparum 50667 R-PFA-9748996 https://reactome.org/PathwayBrowser/#/R-PFA-9748996 GST dimers cleave AZA to 6MP IEA Plasmodium falciparum 50667 R-PFA-9751024 https://reactome.org/PathwayBrowser/#/R-PFA-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Plasmodium falciparum 50667 R-RNO-9748951 https://reactome.org/PathwayBrowser/#/R-RNO-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Rattus norvegicus 50667 R-RNO-9748983 https://reactome.org/PathwayBrowser/#/R-RNO-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Rattus norvegicus 50667 R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 50667 R-RNO-9748996 https://reactome.org/PathwayBrowser/#/R-RNO-9748996 GST dimers cleave AZA to 6MP IEA Rattus norvegicus 50667 R-RNO-9751024 https://reactome.org/PathwayBrowser/#/R-RNO-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Rattus norvegicus 50667 R-RNO-9751037 https://reactome.org/PathwayBrowser/#/R-RNO-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Rattus norvegicus 50667 R-SSC-9748951 https://reactome.org/PathwayBrowser/#/R-SSC-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Sus scrofa 50667 R-SSC-9748983 https://reactome.org/PathwayBrowser/#/R-SSC-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Sus scrofa 50667 R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 50667 R-SSC-9748996 https://reactome.org/PathwayBrowser/#/R-SSC-9748996 GST dimers cleave AZA to 6MP IEA Sus scrofa 50667 R-SSC-9751024 https://reactome.org/PathwayBrowser/#/R-SSC-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Sus scrofa 50667 R-SSC-9751037 https://reactome.org/PathwayBrowser/#/R-SSC-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Sus scrofa 50667 R-XTR-9748983 https://reactome.org/PathwayBrowser/#/R-XTR-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Xenopus tropicalis 50667 R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 50667 R-XTR-9748996 https://reactome.org/PathwayBrowser/#/R-XTR-9748996 GST dimers cleave AZA to 6MP IEA Xenopus tropicalis 50667 R-XTR-9751024 https://reactome.org/PathwayBrowser/#/R-XTR-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Xenopus tropicalis 50667 R-XTR-9751037 https://reactome.org/PathwayBrowser/#/R-XTR-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 50673 R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 50673 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 50673 R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 50673 R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 50673 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 50673 R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 50673 R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 50673 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 50673 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 50673 R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 50673 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 50673 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 50673 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 50673 R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 50673 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 50673 R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 50673 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 50673 R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 50673 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 50673 R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 50690 R-BTA-9705584 https://reactome.org/PathwayBrowser/#/R-BTA-9705584 HMGCR dimer binds statins IEA Bos taurus 50690 R-BTA-9756156 https://reactome.org/PathwayBrowser/#/R-BTA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Bos taurus 50690 R-BTA-9756162 https://reactome.org/PathwayBrowser/#/R-BTA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Bos taurus 50690 R-BTA-9756169 https://reactome.org/PathwayBrowser/#/R-BTA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Bos taurus 50690 R-BTA-9756177 https://reactome.org/PathwayBrowser/#/R-BTA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Bos taurus 50690 R-BTA-9757010 https://reactome.org/PathwayBrowser/#/R-BTA-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Bos taurus 50690 R-BTA-9757139 https://reactome.org/PathwayBrowser/#/R-BTA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Bos taurus 50690 R-CEL-9705584 https://reactome.org/PathwayBrowser/#/R-CEL-9705584 HMGCR dimer binds statins IEA Caenorhabditis elegans 50690 R-CEL-9756177 https://reactome.org/PathwayBrowser/#/R-CEL-9756177 PON1,3 hydrolyse ATVL to ATV IEA Caenorhabditis elegans 50690 R-CEL-9757010 https://reactome.org/PathwayBrowser/#/R-CEL-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Caenorhabditis elegans 50690 R-CEL-9757139 https://reactome.org/PathwayBrowser/#/R-CEL-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Caenorhabditis elegans 50690 R-CFA-9705584 https://reactome.org/PathwayBrowser/#/R-CFA-9705584 HMGCR dimer binds statins IEA Canis familiaris 50690 R-CFA-9756162 https://reactome.org/PathwayBrowser/#/R-CFA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Canis familiaris 50690 R-CFA-9756169 https://reactome.org/PathwayBrowser/#/R-CFA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Canis familiaris 50690 R-CFA-9756177 https://reactome.org/PathwayBrowser/#/R-CFA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Canis familiaris 50690 R-CFA-9757010 https://reactome.org/PathwayBrowser/#/R-CFA-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Canis familiaris 50690 R-CFA-9757139 https://reactome.org/PathwayBrowser/#/R-CFA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Canis familiaris 50690 R-DDI-9705584 https://reactome.org/PathwayBrowser/#/R-DDI-9705584 HMGCR dimer binds statins IEA Dictyostelium discoideum 50690 R-DDI-9756156 https://reactome.org/PathwayBrowser/#/R-DDI-9756156 UGT1A3 lactonizes ATV to ATVL IEA Dictyostelium discoideum 50690 R-DDI-9757139 https://reactome.org/PathwayBrowser/#/R-DDI-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Dictyostelium discoideum 50690 R-DME-9705584 https://reactome.org/PathwayBrowser/#/R-DME-9705584 HMGCR dimer binds statins IEA Drosophila melanogaster 50690 R-DME-9757010 https://reactome.org/PathwayBrowser/#/R-DME-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Drosophila melanogaster 50690 R-DME-9757139 https://reactome.org/PathwayBrowser/#/R-DME-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Drosophila melanogaster 50690 R-DRE-9705584 https://reactome.org/PathwayBrowser/#/R-DRE-9705584 HMGCR dimer binds statins IEA Danio rerio 50690 R-DRE-9756162 https://reactome.org/PathwayBrowser/#/R-DRE-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Danio rerio 50690 R-DRE-9756169 https://reactome.org/PathwayBrowser/#/R-DRE-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Danio rerio 50690 R-DRE-9756177 https://reactome.org/PathwayBrowser/#/R-DRE-9756177 PON1,3 hydrolyse ATVL to ATV IEA Danio rerio 50690 R-DRE-9757010 https://reactome.org/PathwayBrowser/#/R-DRE-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Danio rerio 50690 R-DRE-9757139 https://reactome.org/PathwayBrowser/#/R-DRE-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Danio rerio 50690 R-GGA-9705584 https://reactome.org/PathwayBrowser/#/R-GGA-9705584 HMGCR dimer binds statins IEA Gallus gallus 50690 R-GGA-9756156 https://reactome.org/PathwayBrowser/#/R-GGA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Gallus gallus 50690 R-GGA-9756162 https://reactome.org/PathwayBrowser/#/R-GGA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Gallus gallus 50690 R-GGA-9756169 https://reactome.org/PathwayBrowser/#/R-GGA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Gallus gallus 50690 R-GGA-9756177 https://reactome.org/PathwayBrowser/#/R-GGA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Gallus gallus 50690 R-GGA-9757010 https://reactome.org/PathwayBrowser/#/R-GGA-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Gallus gallus 50690 R-GGA-9757139 https://reactome.org/PathwayBrowser/#/R-GGA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Gallus gallus 50690 R-HSA-9705584 https://reactome.org/PathwayBrowser/#/R-HSA-9705584 HMGCR dimer binds statins TAS Homo sapiens 50690 R-HSA-9756156 https://reactome.org/PathwayBrowser/#/R-HSA-9756156 UGT1A3 lactonizes ATV to ATVL TAS Homo sapiens 50690 R-HSA-9756162 https://reactome.org/PathwayBrowser/#/R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV TAS Homo sapiens 50690 R-HSA-9756169 https://reactome.org/PathwayBrowser/#/R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV TAS Homo sapiens 50690 R-HSA-9756177 https://reactome.org/PathwayBrowser/#/R-HSA-9756177 PON1,3 hydrolyse ATVL to ATV TAS Homo sapiens 50690 R-HSA-9757010 https://reactome.org/PathwayBrowser/#/R-HSA-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol TAS Homo sapiens 50690 R-HSA-9757139 https://reactome.org/PathwayBrowser/#/R-HSA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region TAS Homo sapiens 50690 R-MMU-9705584 https://reactome.org/PathwayBrowser/#/R-MMU-9705584 HMGCR dimer binds statins IEA Mus musculus 50690 R-MMU-9756156 https://reactome.org/PathwayBrowser/#/R-MMU-9756156 UGT1A3 lactonizes ATV to ATVL IEA Mus musculus 50690 R-MMU-9756162 https://reactome.org/PathwayBrowser/#/R-MMU-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Mus musculus 50690 R-MMU-9756169 https://reactome.org/PathwayBrowser/#/R-MMU-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Mus musculus 50690 R-MMU-9756177 https://reactome.org/PathwayBrowser/#/R-MMU-9756177 PON1,3 hydrolyse ATVL to ATV IEA Mus musculus 50690 R-MMU-9757010 https://reactome.org/PathwayBrowser/#/R-MMU-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Mus musculus 50690 R-MMU-9757139 https://reactome.org/PathwayBrowser/#/R-MMU-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Mus musculus 50690 R-PFA-9757139 https://reactome.org/PathwayBrowser/#/R-PFA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Plasmodium falciparum 50690 R-RNO-9705584 https://reactome.org/PathwayBrowser/#/R-RNO-9705584 HMGCR dimer binds statins IEA Rattus norvegicus 50690 R-RNO-9756156 https://reactome.org/PathwayBrowser/#/R-RNO-9756156 UGT1A3 lactonizes ATV to ATVL IEA Rattus norvegicus 50690 R-RNO-9756162 https://reactome.org/PathwayBrowser/#/R-RNO-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Rattus norvegicus 50690 R-RNO-9756169 https://reactome.org/PathwayBrowser/#/R-RNO-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Rattus norvegicus 50690 R-RNO-9756177 https://reactome.org/PathwayBrowser/#/R-RNO-9756177 PON1,3 hydrolyse ATVL to ATV IEA Rattus norvegicus 50690 R-RNO-9757010 https://reactome.org/PathwayBrowser/#/R-RNO-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Rattus norvegicus 50690 R-RNO-9757139 https://reactome.org/PathwayBrowser/#/R-RNO-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Rattus norvegicus 50690 R-SCE-9705584 https://reactome.org/PathwayBrowser/#/R-SCE-9705584 HMGCR dimer binds statins IEA Saccharomyces cerevisiae 50690 R-SCE-9757139 https://reactome.org/PathwayBrowser/#/R-SCE-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Saccharomyces cerevisiae 50690 R-SPO-9705584 https://reactome.org/PathwayBrowser/#/R-SPO-9705584 HMGCR dimer binds statins IEA Schizosaccharomyces pombe 50690 R-SPO-9757139 https://reactome.org/PathwayBrowser/#/R-SPO-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Schizosaccharomyces pombe 50690 R-SSC-9705584 https://reactome.org/PathwayBrowser/#/R-SSC-9705584 HMGCR dimer binds statins IEA Sus scrofa 50690 R-SSC-9756156 https://reactome.org/PathwayBrowser/#/R-SSC-9756156 UGT1A3 lactonizes ATV to ATVL IEA Sus scrofa 50690 R-SSC-9756162 https://reactome.org/PathwayBrowser/#/R-SSC-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Sus scrofa 50690 R-SSC-9756169 https://reactome.org/PathwayBrowser/#/R-SSC-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Sus scrofa 50690 R-SSC-9756177 https://reactome.org/PathwayBrowser/#/R-SSC-9756177 PON1,3 hydrolyse ATVL to ATV IEA Sus scrofa 50690 R-SSC-9757010 https://reactome.org/PathwayBrowser/#/R-SSC-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Sus scrofa 50690 R-SSC-9757139 https://reactome.org/PathwayBrowser/#/R-SSC-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Sus scrofa 50690 R-XTR-9705584 https://reactome.org/PathwayBrowser/#/R-XTR-9705584 HMGCR dimer binds statins IEA Xenopus tropicalis 50690 R-XTR-9756162 https://reactome.org/PathwayBrowser/#/R-XTR-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Xenopus tropicalis 50690 R-XTR-9756169 https://reactome.org/PathwayBrowser/#/R-XTR-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Xenopus tropicalis 50690 R-XTR-9756177 https://reactome.org/PathwayBrowser/#/R-XTR-9756177 PON1,3 hydrolyse ATVL to ATV IEA Xenopus tropicalis 50690 R-XTR-9757010 https://reactome.org/PathwayBrowser/#/R-XTR-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Xenopus tropicalis 50690 R-XTR-9757139 https://reactome.org/PathwayBrowser/#/R-XTR-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Xenopus tropicalis 50693 R-BTA-9629679 https://reactome.org/PathwayBrowser/#/R-BTA-9629679 PDE3A inhibitors bind PDE3A IEA Bos taurus 50693 R-CEL-9629679 https://reactome.org/PathwayBrowser/#/R-CEL-9629679 PDE3A inhibitors bind PDE3A IEA Caenorhabditis elegans 50693 R-CFA-9629679 https://reactome.org/PathwayBrowser/#/R-CFA-9629679 PDE3A inhibitors bind PDE3A IEA Canis familiaris 50693 R-DDI-9629679 https://reactome.org/PathwayBrowser/#/R-DDI-9629679 PDE3A inhibitors bind PDE3A IEA Dictyostelium discoideum 50693 R-GGA-9629679 https://reactome.org/PathwayBrowser/#/R-GGA-9629679 PDE3A inhibitors bind PDE3A IEA Gallus gallus 50693 R-HSA-9629679 https://reactome.org/PathwayBrowser/#/R-HSA-9629679 PDE3A inhibitors bind PDE3A TAS Homo sapiens 50693 R-MMU-9629679 https://reactome.org/PathwayBrowser/#/R-MMU-9629679 PDE3A inhibitors bind PDE3A IEA Mus musculus 50693 R-PFA-9629679 https://reactome.org/PathwayBrowser/#/R-PFA-9629679 PDE3A inhibitors bind PDE3A IEA Plasmodium falciparum 50693 R-RNO-9629679 https://reactome.org/PathwayBrowser/#/R-RNO-9629679 PDE3A inhibitors bind PDE3A IEA Rattus norvegicus 50693 R-SSC-9629679 https://reactome.org/PathwayBrowser/#/R-SSC-9629679 PDE3A inhibitors bind PDE3A IEA Sus scrofa 507393 R-BTA-1655453 https://reactome.org/PathwayBrowser/#/R-BTA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Bos taurus 507393 R-BTA-351987 https://reactome.org/PathwayBrowser/#/R-BTA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Bos taurus 507393 R-BTA-6787757 https://reactome.org/PathwayBrowser/#/R-BTA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Bos taurus 507393 R-CEL-159431 https://reactome.org/PathwayBrowser/#/R-CEL-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Caenorhabditis elegans 507393 R-CEL-1655453 https://reactome.org/PathwayBrowser/#/R-CEL-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Caenorhabditis elegans 507393 R-CEL-192312 https://reactome.org/PathwayBrowser/#/R-CEL-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Caenorhabditis elegans 507393 R-CEL-193491 https://reactome.org/PathwayBrowser/#/R-CEL-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Caenorhabditis elegans 507393 R-CFA-159431 https://reactome.org/PathwayBrowser/#/R-CFA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Canis familiaris 507393 R-CFA-1655453 https://reactome.org/PathwayBrowser/#/R-CFA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Canis familiaris 507393 R-CFA-192312 https://reactome.org/PathwayBrowser/#/R-CFA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Canis familiaris 507393 R-CFA-193491 https://reactome.org/PathwayBrowser/#/R-CFA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Canis familiaris 507393 R-CFA-351987 https://reactome.org/PathwayBrowser/#/R-CFA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Canis familiaris 507393 R-CFA-6787757 https://reactome.org/PathwayBrowser/#/R-CFA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Canis familiaris 507393 R-DDI-1655453 https://reactome.org/PathwayBrowser/#/R-DDI-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Dictyostelium discoideum 507393 R-DME-6787757 https://reactome.org/PathwayBrowser/#/R-DME-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Drosophila melanogaster 507393 R-DRE-1655453 https://reactome.org/PathwayBrowser/#/R-DRE-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Danio rerio 507393 R-DRE-351987 https://reactome.org/PathwayBrowser/#/R-DRE-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Danio rerio 507393 R-GGA-159431 https://reactome.org/PathwayBrowser/#/R-GGA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Gallus gallus 507393 R-GGA-192312 https://reactome.org/PathwayBrowser/#/R-GGA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Gallus gallus 507393 R-GGA-193491 https://reactome.org/PathwayBrowser/#/R-GGA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Gallus gallus 507393 R-GGA-351987 https://reactome.org/PathwayBrowser/#/R-GGA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Gallus gallus 507393 R-GGA-6787757 https://reactome.org/PathwayBrowser/#/R-GGA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Gallus gallus 507393 R-HSA-159431 https://reactome.org/PathwayBrowser/#/R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine TAS Homo sapiens 507393 R-HSA-1655453 https://reactome.org/PathwayBrowser/#/R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU TAS Homo sapiens 507393 R-HSA-192312 https://reactome.org/PathwayBrowser/#/R-HSA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate TAS Homo sapiens 507393 R-HSA-193491 https://reactome.org/PathwayBrowser/#/R-HSA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate TAS Homo sapiens 507393 R-HSA-351987 https://reactome.org/PathwayBrowser/#/R-HSA-351987 SLC6A6-mediated uptake of taurine and beta-alanine TAS Homo sapiens 507393 R-HSA-6787757 https://reactome.org/PathwayBrowser/#/R-HSA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs TAS Homo sapiens 507393 R-MMU-159431 https://reactome.org/PathwayBrowser/#/R-MMU-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Mus musculus 507393 R-MMU-1655453 https://reactome.org/PathwayBrowser/#/R-MMU-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Mus musculus 507393 R-MMU-192312 https://reactome.org/PathwayBrowser/#/R-MMU-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Mus musculus 507393 R-MMU-193491 https://reactome.org/PathwayBrowser/#/R-MMU-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Mus musculus 507393 R-MMU-351987 https://reactome.org/PathwayBrowser/#/R-MMU-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Mus musculus 507393 R-MMU-6787757 https://reactome.org/PathwayBrowser/#/R-MMU-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Mus musculus 507393 R-PFA-351987 https://reactome.org/PathwayBrowser/#/R-PFA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Plasmodium falciparum 507393 R-RNO-159431 https://reactome.org/PathwayBrowser/#/R-RNO-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Rattus norvegicus 507393 R-RNO-1655453 https://reactome.org/PathwayBrowser/#/R-RNO-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Rattus norvegicus 507393 R-RNO-192312 https://reactome.org/PathwayBrowser/#/R-RNO-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Rattus norvegicus 507393 R-RNO-193491 https://reactome.org/PathwayBrowser/#/R-RNO-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Rattus norvegicus 507393 R-RNO-351987 https://reactome.org/PathwayBrowser/#/R-RNO-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Rattus norvegicus 507393 R-RNO-6787757 https://reactome.org/PathwayBrowser/#/R-RNO-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Rattus norvegicus 507393 R-SSC-159431 https://reactome.org/PathwayBrowser/#/R-SSC-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Sus scrofa 507393 R-SSC-1655453 https://reactome.org/PathwayBrowser/#/R-SSC-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Sus scrofa 507393 R-SSC-192312 https://reactome.org/PathwayBrowser/#/R-SSC-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Sus scrofa 507393 R-SSC-193491 https://reactome.org/PathwayBrowser/#/R-SSC-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Sus scrofa 507393 R-SSC-351987 https://reactome.org/PathwayBrowser/#/R-SSC-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Sus scrofa 507393 R-SSC-6787757 https://reactome.org/PathwayBrowser/#/R-SSC-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Sus scrofa 507393 R-XTR-159431 https://reactome.org/PathwayBrowser/#/R-XTR-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Xenopus tropicalis 507393 R-XTR-1655453 https://reactome.org/PathwayBrowser/#/R-XTR-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Xenopus tropicalis 507393 R-XTR-192312 https://reactome.org/PathwayBrowser/#/R-XTR-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Xenopus tropicalis 507393 R-XTR-193491 https://reactome.org/PathwayBrowser/#/R-XTR-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Xenopus tropicalis 507393 R-XTR-351987 https://reactome.org/PathwayBrowser/#/R-XTR-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Xenopus tropicalis 507393 R-XTR-6787757 https://reactome.org/PathwayBrowser/#/R-XTR-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Xenopus tropicalis 50746 R-BTA-5693977 https://reactome.org/PathwayBrowser/#/R-BTA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Bos taurus 50746 R-BTA-5694018 https://reactome.org/PathwayBrowser/#/R-BTA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Bos taurus 50746 R-CEL-5693977 https://reactome.org/PathwayBrowser/#/R-CEL-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Caenorhabditis elegans 50746 R-CEL-5694018 https://reactome.org/PathwayBrowser/#/R-CEL-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Caenorhabditis elegans 50746 R-CFA-5693977 https://reactome.org/PathwayBrowser/#/R-CFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Canis familiaris 50746 R-CFA-5694018 https://reactome.org/PathwayBrowser/#/R-CFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Canis familiaris 50746 R-DDI-5693977 https://reactome.org/PathwayBrowser/#/R-DDI-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Dictyostelium discoideum 50746 R-DDI-5694018 https://reactome.org/PathwayBrowser/#/R-DDI-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Dictyostelium discoideum 50746 R-DME-5693977 https://reactome.org/PathwayBrowser/#/R-DME-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Drosophila melanogaster 50746 R-DME-5694018 https://reactome.org/PathwayBrowser/#/R-DME-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Drosophila melanogaster 50746 R-DRE-5693977 https://reactome.org/PathwayBrowser/#/R-DRE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Danio rerio 50746 R-DRE-5694018 https://reactome.org/PathwayBrowser/#/R-DRE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Danio rerio 50746 R-GGA-5694018 https://reactome.org/PathwayBrowser/#/R-GGA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Gallus gallus 50746 R-HSA-5693977 https://reactome.org/PathwayBrowser/#/R-HSA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF TAS Homo sapiens 50746 R-HSA-5694018 https://reactome.org/PathwayBrowser/#/R-HSA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate TAS Homo sapiens 50746 R-MMU-5693977 https://reactome.org/PathwayBrowser/#/R-MMU-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Mus musculus 50746 R-MMU-5694018 https://reactome.org/PathwayBrowser/#/R-MMU-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Mus musculus 50746 R-PFA-5693977 https://reactome.org/PathwayBrowser/#/R-PFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Plasmodium falciparum 50746 R-PFA-5694018 https://reactome.org/PathwayBrowser/#/R-PFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Plasmodium falciparum 50746 R-RNO-5693977 https://reactome.org/PathwayBrowser/#/R-RNO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Rattus norvegicus 50746 R-RNO-5694018 https://reactome.org/PathwayBrowser/#/R-RNO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Rattus norvegicus 50746 R-SCE-5693977 https://reactome.org/PathwayBrowser/#/R-SCE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Saccharomyces cerevisiae 50746 R-SCE-5694018 https://reactome.org/PathwayBrowser/#/R-SCE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Saccharomyces cerevisiae 50746 R-SPO-5693977 https://reactome.org/PathwayBrowser/#/R-SPO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Schizosaccharomyces pombe 50746 R-SPO-5694018 https://reactome.org/PathwayBrowser/#/R-SPO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Schizosaccharomyces pombe 50746 R-SSC-5693977 https://reactome.org/PathwayBrowser/#/R-SSC-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Sus scrofa 50746 R-SSC-5694018 https://reactome.org/PathwayBrowser/#/R-SSC-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Sus scrofa 50746 R-XTR-5693977 https://reactome.org/PathwayBrowser/#/R-XTR-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Xenopus tropicalis 50746 R-XTR-5694018 https://reactome.org/PathwayBrowser/#/R-XTR-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Xenopus tropicalis 50749 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 50749 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 50749 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 50749 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 50749 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 50749 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 50749 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 50749 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 50749 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 50749 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 50749 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 50774 R-HSA-2162191 https://reactome.org/PathwayBrowser/#/R-HSA-2162191 Unknown enzyme hydroxylates DMPhOH IEA Homo sapiens 50774 R-HSA-2162195 https://reactome.org/PathwayBrowser/#/R-HSA-2162195 Unknown enzyme decarboxylates MHDB IEA Homo sapiens 50824 R-CFA-2247510 https://reactome.org/PathwayBrowser/#/R-CFA-2247510 MARCO:ligand is endocytosed IEA Canis familiaris 50824 R-HSA-2173781 https://reactome.org/PathwayBrowser/#/R-HSA-2173781 MARCO (SCARA2) binds ligands IEA Homo sapiens 50824 R-HSA-2247510 https://reactome.org/PathwayBrowser/#/R-HSA-2247510 MARCO:ligand is endocytosed TAS Homo sapiens 50824 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 50824 R-MMU-2247510 https://reactome.org/PathwayBrowser/#/R-MMU-2247510 MARCO:ligand is endocytosed IEA Mus musculus 50824 R-RNO-2247510 https://reactome.org/PathwayBrowser/#/R-RNO-2247510 MARCO:ligand is endocytosed IEA Rattus norvegicus 50828 R-CFA-2247510 https://reactome.org/PathwayBrowser/#/R-CFA-2247510 MARCO:ligand is endocytosed IEA Canis familiaris 50828 R-HSA-2173781 https://reactome.org/PathwayBrowser/#/R-HSA-2173781 MARCO (SCARA2) binds ligands IEA Homo sapiens 50828 R-HSA-2247510 https://reactome.org/PathwayBrowser/#/R-HSA-2247510 MARCO:ligand is endocytosed TAS Homo sapiens 50828 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 50828 R-MMU-2247510 https://reactome.org/PathwayBrowser/#/R-MMU-2247510 MARCO:ligand is endocytosed IEA Mus musculus 50828 R-RNO-2247510 https://reactome.org/PathwayBrowser/#/R-RNO-2247510 MARCO:ligand is endocytosed IEA Rattus norvegicus 50904 R-BTA-2454192 https://reactome.org/PathwayBrowser/#/R-BTA-2454192 Allergen dependent IgE bound FCERI aggregation IEA Bos taurus 50904 R-BTA-2454208 https://reactome.org/PathwayBrowser/#/R-BTA-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Bos taurus 50904 R-BTA-2454240 https://reactome.org/PathwayBrowser/#/R-BTA-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Bos taurus 50904 R-BTA-2730833 https://reactome.org/PathwayBrowser/#/R-BTA-2730833 Phosphorylation of TEC kinases by p-SYK IEA Bos taurus 50904 R-BTA-2730843 https://reactome.org/PathwayBrowser/#/R-BTA-2730843 Phosphorylation of LAT by p-SYK IEA Bos taurus 50904 R-BTA-2730851 https://reactome.org/PathwayBrowser/#/R-BTA-2730851 Phosphorylation of SLP-76 by p-SYK IEA Bos taurus 50904 R-BTA-2730882 https://reactome.org/PathwayBrowser/#/R-BTA-2730882 Phosphorylation of PKC-theta IEA Bos taurus 50904 R-BTA-2730884 https://reactome.org/PathwayBrowser/#/R-BTA-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Bos taurus 50904 R-BTA-2730886 https://reactome.org/PathwayBrowser/#/R-BTA-2730886 Phosphorylation of SHC by SYK kinase IEA Bos taurus 50904 R-CFA-2454192 https://reactome.org/PathwayBrowser/#/R-CFA-2454192 Allergen dependent IgE bound FCERI aggregation IEA Canis familiaris 50904 R-CFA-2454208 https://reactome.org/PathwayBrowser/#/R-CFA-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Canis familiaris 50904 R-CFA-2454240 https://reactome.org/PathwayBrowser/#/R-CFA-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Canis familiaris 50904 R-CFA-2730833 https://reactome.org/PathwayBrowser/#/R-CFA-2730833 Phosphorylation of TEC kinases by p-SYK IEA Canis familiaris 50904 R-CFA-2730843 https://reactome.org/PathwayBrowser/#/R-CFA-2730843 Phosphorylation of LAT by p-SYK IEA Canis familiaris 50904 R-CFA-2730851 https://reactome.org/PathwayBrowser/#/R-CFA-2730851 Phosphorylation of SLP-76 by p-SYK IEA Canis familiaris 50904 R-CFA-2730882 https://reactome.org/PathwayBrowser/#/R-CFA-2730882 Phosphorylation of PKC-theta IEA Canis familiaris 50904 R-CFA-2730884 https://reactome.org/PathwayBrowser/#/R-CFA-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Canis familiaris 50904 R-CFA-2730886 https://reactome.org/PathwayBrowser/#/R-CFA-2730886 Phosphorylation of SHC by SYK kinase IEA Canis familiaris 50904 R-HSA-2454192 https://reactome.org/PathwayBrowser/#/R-HSA-2454192 Allergen dependent IgE bound FCERI aggregation TAS Homo sapiens 50904 R-HSA-2454208 https://reactome.org/PathwayBrowser/#/R-HSA-2454208 Phosphorylation of beta and gamma subunits by LYN TAS Homo sapiens 50904 R-HSA-2454239 https://reactome.org/PathwayBrowser/#/R-HSA-2454239 Phosphorylation of SYK IEA Homo sapiens 50904 R-HSA-2454240 https://reactome.org/PathwayBrowser/#/R-HSA-2454240 Recruitment of SYK to p-FCERI gamma subunit TAS Homo sapiens 50904 R-HSA-2730833 https://reactome.org/PathwayBrowser/#/R-HSA-2730833 Phosphorylation of TEC kinases by p-SYK TAS Homo sapiens 50904 R-HSA-2730843 https://reactome.org/PathwayBrowser/#/R-HSA-2730843 Phosphorylation of LAT by p-SYK TAS Homo sapiens 50904 R-HSA-2730851 https://reactome.org/PathwayBrowser/#/R-HSA-2730851 Phosphorylation of SLP-76 by p-SYK TAS Homo sapiens 50904 R-HSA-2730860 https://reactome.org/PathwayBrowser/#/R-HSA-2730860 Phosphorylation of GAB2 by SYK/FYN IEA Homo sapiens 50904 R-HSA-2730882 https://reactome.org/PathwayBrowser/#/R-HSA-2730882 Phosphorylation of PKC-theta TAS Homo sapiens 50904 R-HSA-2730884 https://reactome.org/PathwayBrowser/#/R-HSA-2730884 Phosphorylation of NTAL by p-SYK/Lyn TAS Homo sapiens 50904 R-HSA-2730886 https://reactome.org/PathwayBrowser/#/R-HSA-2730886 Phosphorylation of SHC by SYK kinase TAS Homo sapiens 50904 R-HSA-2730888 https://reactome.org/PathwayBrowser/#/R-HSA-2730888 Phosphorylation of PLC-gamma IEA Homo sapiens 50904 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus 50904 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus 50904 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus 50904 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus 50904 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus 50904 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus 50904 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus 50904 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus 50904 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus 50904 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus 50904 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus 50904 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus 50904 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus 50904 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus 50904 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus 50904 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus 50904 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus 50904 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus 50904 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa 50904 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa 50904 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa 50904 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa 50904 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa 50904 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa 50904 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa 50904 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa 50904 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa 50924 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 50924 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 50924 R-BTA-5213464 https://reactome.org/PathwayBrowser/#/R-BTA-5213464 RIPK1 is phosphorylated IEA Bos taurus 50924 R-BTA-5213466 https://reactome.org/PathwayBrowser/#/R-BTA-5213466 RIPK3 is phosphorylated IEA Bos taurus 50924 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 50924 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 50924 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 50924 R-BTA-9693978 https://reactome.org/PathwayBrowser/#/R-BTA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Bos taurus 50924 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 50924 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 50924 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 50924 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 50924 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 50924 R-CFA-5213464 https://reactome.org/PathwayBrowser/#/R-CFA-5213464 RIPK1 is phosphorylated IEA Canis familiaris 50924 R-CFA-5213466 https://reactome.org/PathwayBrowser/#/R-CFA-5213466 RIPK3 is phosphorylated IEA Canis familiaris 50924 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 50924 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 50924 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 50924 R-CFA-9693978 https://reactome.org/PathwayBrowser/#/R-CFA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Canis familiaris 50924 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 50924 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 50924 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 50924 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 50924 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 50924 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 50924 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 50924 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 50924 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 50924 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 50924 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 50924 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 50924 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 50924 R-HSA-5213464 https://reactome.org/PathwayBrowser/#/R-HSA-5213464 RIPK1 is phosphorylated TAS Homo sapiens 50924 R-HSA-5213466 https://reactome.org/PathwayBrowser/#/R-HSA-5213466 RIPK3 is phosphorylated TAS Homo sapiens 50924 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 50924 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 50924 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 50924 R-HSA-9669874 https://reactome.org/PathwayBrowser/#/R-HSA-9669874 Sorafenib-resistant KIT mutants do not bind sorafenib TAS Homo sapiens 50924 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 50924 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 50924 R-HSA-9674414 https://reactome.org/PathwayBrowser/#/R-HSA-9674414 Sorafenib-resistant PDGFR mutants don't bind sorefenib TAS Homo sapiens 50924 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 50924 R-HSA-9693978 https://reactome.org/PathwayBrowser/#/R-HSA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 TAS Homo sapiens 50924 R-HSA-9695831 https://reactome.org/PathwayBrowser/#/R-HSA-9695831 FLT3 binds type II TKI TAS Homo sapiens 50924 R-HSA-9702510 https://reactome.org/PathwayBrowser/#/R-HSA-9702510 FLT mutants bind type II TKIs TAS Homo sapiens 50924 R-HSA-9702623 https://reactome.org/PathwayBrowser/#/R-HSA-9702623 sorafenib-resistant FLT3 mutants don't bind sorafenib TAS Homo sapiens 50924 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 50924 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 50924 R-MMU-5213464 https://reactome.org/PathwayBrowser/#/R-MMU-5213464 RIPK1 is phosphorylated IEA Mus musculus 50924 R-MMU-5213466 https://reactome.org/PathwayBrowser/#/R-MMU-5213466 RIPK3 is phosphorylated IEA Mus musculus 50924 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 50924 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 50924 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 50924 R-MMU-9693978 https://reactome.org/PathwayBrowser/#/R-MMU-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Mus musculus 50924 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 50924 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 50924 R-RNO-5213464 https://reactome.org/PathwayBrowser/#/R-RNO-5213464 RIPK1 is phosphorylated IEA Rattus norvegicus 50924 R-RNO-5213466 https://reactome.org/PathwayBrowser/#/R-RNO-5213466 RIPK3 is phosphorylated IEA Rattus norvegicus 50924 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 50924 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 50924 R-RNO-9693978 https://reactome.org/PathwayBrowser/#/R-RNO-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Rattus norvegicus 50924 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 50924 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 50924 R-SSC-5213464 https://reactome.org/PathwayBrowser/#/R-SSC-5213464 RIPK1 is phosphorylated IEA Sus scrofa 50924 R-SSC-5213466 https://reactome.org/PathwayBrowser/#/R-SSC-5213466 RIPK3 is phosphorylated IEA Sus scrofa 50924 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 50924 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 50924 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 50924 R-SSC-9693978 https://reactome.org/PathwayBrowser/#/R-SSC-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Sus scrofa 50924 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 50924 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 50924 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 50924 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 50998 R-BTA-5676637 https://reactome.org/PathwayBrowser/#/R-BTA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Bos taurus 50998 R-CEL-5676637 https://reactome.org/PathwayBrowser/#/R-CEL-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Caenorhabditis elegans 50998 R-CFA-5676637 https://reactome.org/PathwayBrowser/#/R-CFA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Canis familiaris 50998 R-CFA-8957389 https://reactome.org/PathwayBrowser/#/R-CFA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Canis familiaris 50998 R-DDI-5676637 https://reactome.org/PathwayBrowser/#/R-DDI-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Dictyostelium discoideum 50998 R-DDI-8957389 https://reactome.org/PathwayBrowser/#/R-DDI-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Dictyostelium discoideum 50998 R-DME-5676637 https://reactome.org/PathwayBrowser/#/R-DME-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Drosophila melanogaster 50998 R-DME-8957389 https://reactome.org/PathwayBrowser/#/R-DME-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Drosophila melanogaster 50998 R-DRE-5676637 https://reactome.org/PathwayBrowser/#/R-DRE-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Danio rerio 50998 R-GGA-5676637 https://reactome.org/PathwayBrowser/#/R-GGA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Gallus gallus 50998 R-GGA-8957389 https://reactome.org/PathwayBrowser/#/R-GGA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Gallus gallus 50998 R-HSA-5676637 https://reactome.org/PathwayBrowser/#/R-HSA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA TAS Homo sapiens 50998 R-HSA-8957389 https://reactome.org/PathwayBrowser/#/R-HSA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA TAS Homo sapiens 50998 R-MMU-5676637 https://reactome.org/PathwayBrowser/#/R-MMU-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Mus musculus 50998 R-PFA-5676637 https://reactome.org/PathwayBrowser/#/R-PFA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Plasmodium falciparum 50998 R-RNO-5676637 https://reactome.org/PathwayBrowser/#/R-RNO-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Rattus norvegicus 50998 R-RNO-8957389 https://reactome.org/PathwayBrowser/#/R-RNO-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Rattus norvegicus 50998 R-SCE-5676637 https://reactome.org/PathwayBrowser/#/R-SCE-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Saccharomyces cerevisiae 50998 R-SPO-5676637 https://reactome.org/PathwayBrowser/#/R-SPO-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Schizosaccharomyces pombe 50998 R-SSC-5676637 https://reactome.org/PathwayBrowser/#/R-SSC-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Sus scrofa 50998 R-SSC-8957389 https://reactome.org/PathwayBrowser/#/R-SSC-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Sus scrofa 50998 R-XTR-5676637 https://reactome.org/PathwayBrowser/#/R-XTR-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Xenopus tropicalis 51050 R-CFA-2247510 https://reactome.org/PathwayBrowser/#/R-CFA-2247510 MARCO:ligand is endocytosed IEA Canis familiaris 51050 R-HSA-2173781 https://reactome.org/PathwayBrowser/#/R-HSA-2173781 MARCO (SCARA2) binds ligands IEA Homo sapiens 51050 R-HSA-2247510 https://reactome.org/PathwayBrowser/#/R-HSA-2247510 MARCO:ligand is endocytosed TAS Homo sapiens 51050 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 51050 R-MMU-2247510 https://reactome.org/PathwayBrowser/#/R-MMU-2247510 MARCO:ligand is endocytosed IEA Mus musculus 51050 R-RNO-2247510 https://reactome.org/PathwayBrowser/#/R-RNO-2247510 MARCO:ligand is endocytosed IEA Rattus norvegicus 51230 R-BTA-9718020 https://reactome.org/PathwayBrowser/#/R-BTA-9718020 PTGFR binds PTGFR agonists IEA Bos taurus 51230 R-CFA-9718020 https://reactome.org/PathwayBrowser/#/R-CFA-9718020 PTGFR binds PTGFR agonists IEA Canis familiaris 51230 R-DME-9718020 https://reactome.org/PathwayBrowser/#/R-DME-9718020 PTGFR binds PTGFR agonists IEA Drosophila melanogaster 51230 R-DRE-9718020 https://reactome.org/PathwayBrowser/#/R-DRE-9718020 PTGFR binds PTGFR agonists IEA Danio rerio 51230 R-GGA-9718020 https://reactome.org/PathwayBrowser/#/R-GGA-9718020 PTGFR binds PTGFR agonists IEA Gallus gallus 51230 R-HSA-9718020 https://reactome.org/PathwayBrowser/#/R-HSA-9718020 PTGFR binds PTGFR agonists TAS Homo sapiens 51230 R-MMU-9718020 https://reactome.org/PathwayBrowser/#/R-MMU-9718020 PTGFR binds PTGFR agonists IEA Mus musculus 51230 R-RNO-9718020 https://reactome.org/PathwayBrowser/#/R-RNO-9718020 PTGFR binds PTGFR agonists IEA Rattus norvegicus 51230 R-SSC-9718020 https://reactome.org/PathwayBrowser/#/R-SSC-9718020 PTGFR binds PTGFR agonists IEA Sus scrofa 51230 R-XTR-9718020 https://reactome.org/PathwayBrowser/#/R-XTR-9718020 PTGFR binds PTGFR agonists IEA Xenopus tropicalis 51341 R-BTA-389632 https://reactome.org/PathwayBrowser/#/R-BTA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 51341 R-BTA-389897 https://reactome.org/PathwayBrowser/#/R-BTA-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Bos taurus 51341 R-CEL-389632 https://reactome.org/PathwayBrowser/#/R-CEL-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 51341 R-CEL-389897 https://reactome.org/PathwayBrowser/#/R-CEL-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Caenorhabditis elegans 51341 R-CFA-389632 https://reactome.org/PathwayBrowser/#/R-CFA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 51341 R-DME-389632 https://reactome.org/PathwayBrowser/#/R-DME-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 51341 R-DME-389897 https://reactome.org/PathwayBrowser/#/R-DME-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Drosophila melanogaster 51341 R-DRE-389897 https://reactome.org/PathwayBrowser/#/R-DRE-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Danio rerio 51341 R-GGA-389632 https://reactome.org/PathwayBrowser/#/R-GGA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 51341 R-GGA-389897 https://reactome.org/PathwayBrowser/#/R-GGA-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Gallus gallus 51341 R-HSA-389632 https://reactome.org/PathwayBrowser/#/R-HSA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 51341 R-HSA-389897 https://reactome.org/PathwayBrowser/#/R-HSA-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA TAS Homo sapiens 51341 R-MMU-389632 https://reactome.org/PathwayBrowser/#/R-MMU-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 51341 R-MMU-389897 https://reactome.org/PathwayBrowser/#/R-MMU-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Mus musculus 51341 R-RNO-389632 https://reactome.org/PathwayBrowser/#/R-RNO-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 51341 R-RNO-389897 https://reactome.org/PathwayBrowser/#/R-RNO-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Rattus norvegicus 51341 R-SCE-389632 https://reactome.org/PathwayBrowser/#/R-SCE-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 51341 R-SSC-389632 https://reactome.org/PathwayBrowser/#/R-SSC-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 51341 R-XTR-389632 https://reactome.org/PathwayBrowser/#/R-XTR-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 51341 R-XTR-389897 https://reactome.org/PathwayBrowser/#/R-XTR-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Xenopus tropicalis 5163 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 5163 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 5163 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 5163 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 5163 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 5163 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 5163 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 5163 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 5163 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 5163 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 5163 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 5163 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 51985 R-BTA-2046084 https://reactome.org/PathwayBrowser/#/R-BTA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Bos taurus 51985 R-BTA-2046085 https://reactome.org/PathwayBrowser/#/R-BTA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Bos taurus 51985 R-CEL-2046084 https://reactome.org/PathwayBrowser/#/R-CEL-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Caenorhabditis elegans 51985 R-CFA-2046084 https://reactome.org/PathwayBrowser/#/R-CFA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Canis familiaris 51985 R-CFA-2046085 https://reactome.org/PathwayBrowser/#/R-CFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Canis familiaris 51985 R-DDI-2046085 https://reactome.org/PathwayBrowser/#/R-DDI-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Dictyostelium discoideum 51985 R-DRE-2046084 https://reactome.org/PathwayBrowser/#/R-DRE-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Danio rerio 51985 R-DRE-2046085 https://reactome.org/PathwayBrowser/#/R-DRE-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Danio rerio 51985 R-GGA-2046084 https://reactome.org/PathwayBrowser/#/R-GGA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Gallus gallus 51985 R-GGA-2046085 https://reactome.org/PathwayBrowser/#/R-GGA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Gallus gallus 51985 R-HSA-2046084 https://reactome.org/PathwayBrowser/#/R-HSA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA TAS Homo sapiens 51985 R-HSA-2046085 https://reactome.org/PathwayBrowser/#/R-HSA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA TAS Homo sapiens 51985 R-MMU-2046084 https://reactome.org/PathwayBrowser/#/R-MMU-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Mus musculus 51985 R-MMU-2046085 https://reactome.org/PathwayBrowser/#/R-MMU-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Mus musculus 51985 R-PFA-2046085 https://reactome.org/PathwayBrowser/#/R-PFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Plasmodium falciparum 51985 R-RNO-2046084 https://reactome.org/PathwayBrowser/#/R-RNO-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Rattus norvegicus 51985 R-RNO-2046085 https://reactome.org/PathwayBrowser/#/R-RNO-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Rattus norvegicus 51985 R-SSC-2046084 https://reactome.org/PathwayBrowser/#/R-SSC-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Sus scrofa 51985 R-SSC-2046085 https://reactome.org/PathwayBrowser/#/R-SSC-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Sus scrofa 51985 R-XTR-2046085 https://reactome.org/PathwayBrowser/#/R-XTR-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Xenopus tropicalis 52050 R-BTA-192331 https://reactome.org/PathwayBrowser/#/R-BTA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Bos taurus 52050 R-BTA-193455 https://reactome.org/PathwayBrowser/#/R-BTA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 52050 R-BTA-193763 https://reactome.org/PathwayBrowser/#/R-BTA-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Bos taurus 52050 R-CEL-192331 https://reactome.org/PathwayBrowser/#/R-CEL-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Caenorhabditis elegans 52050 R-CEL-193455 https://reactome.org/PathwayBrowser/#/R-CEL-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 52050 R-CEL-193763 https://reactome.org/PathwayBrowser/#/R-CEL-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Caenorhabditis elegans 52050 R-CFA-192331 https://reactome.org/PathwayBrowser/#/R-CFA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Canis familiaris 52050 R-CFA-193455 https://reactome.org/PathwayBrowser/#/R-CFA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 52050 R-DDI-192331 https://reactome.org/PathwayBrowser/#/R-DDI-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Dictyostelium discoideum 52050 R-DDI-193455 https://reactome.org/PathwayBrowser/#/R-DDI-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 52050 R-DME-192331 https://reactome.org/PathwayBrowser/#/R-DME-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Drosophila melanogaster 52050 R-DME-193455 https://reactome.org/PathwayBrowser/#/R-DME-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 52050 R-DME-193763 https://reactome.org/PathwayBrowser/#/R-DME-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Drosophila melanogaster 52050 R-DRE-193763 https://reactome.org/PathwayBrowser/#/R-DRE-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Danio rerio 52050 R-GGA-192331 https://reactome.org/PathwayBrowser/#/R-GGA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Gallus gallus 52050 R-GGA-193455 https://reactome.org/PathwayBrowser/#/R-GGA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 52050 R-GGA-193763 https://reactome.org/PathwayBrowser/#/R-GGA-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Gallus gallus 52050 R-HSA-192331 https://reactome.org/PathwayBrowser/#/R-HSA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA TAS Homo sapiens 52050 R-HSA-193455 https://reactome.org/PathwayBrowser/#/R-HSA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 52050 R-HSA-193763 https://reactome.org/PathwayBrowser/#/R-HSA-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA TAS Homo sapiens 52050 R-MMU-192331 https://reactome.org/PathwayBrowser/#/R-MMU-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Mus musculus 52050 R-MMU-193455 https://reactome.org/PathwayBrowser/#/R-MMU-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 52050 R-MMU-193763 https://reactome.org/PathwayBrowser/#/R-MMU-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Mus musculus 52050 R-RNO-192331 https://reactome.org/PathwayBrowser/#/R-RNO-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Rattus norvegicus 52050 R-RNO-193455 https://reactome.org/PathwayBrowser/#/R-RNO-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 52050 R-RNO-193763 https://reactome.org/PathwayBrowser/#/R-RNO-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Rattus norvegicus 52050 R-XTR-193763 https://reactome.org/PathwayBrowser/#/R-XTR-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Xenopus tropicalis 52075 R-HSA-8956427 https://reactome.org/PathwayBrowser/#/R-HSA-8956427 RETSAT reduces atROL to at-13,14-dhROL IEA Homo sapiens 52075 R-MMU-8956439 https://reactome.org/PathwayBrowser/#/R-MMU-8956439 Retsat reduces atROL to at-13,14-dhROL TAS Mus musculus 52255 R-BTA-2424243 https://reactome.org/PathwayBrowser/#/R-BTA-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Bos taurus 52255 R-CEL-2424243 https://reactome.org/PathwayBrowser/#/R-CEL-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Caenorhabditis elegans 52255 R-CFA-2424243 https://reactome.org/PathwayBrowser/#/R-CFA-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Canis familiaris 52255 R-DRE-2424243 https://reactome.org/PathwayBrowser/#/R-DRE-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Danio rerio 52255 R-GGA-2424243 https://reactome.org/PathwayBrowser/#/R-GGA-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Gallus gallus 52255 R-HSA-2424243 https://reactome.org/PathwayBrowser/#/R-HSA-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ TAS Homo sapiens 52255 R-MMU-2424243 https://reactome.org/PathwayBrowser/#/R-MMU-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Mus musculus 52255 R-RNO-2424243 https://reactome.org/PathwayBrowser/#/R-RNO-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Rattus norvegicus 52255 R-SSC-2424243 https://reactome.org/PathwayBrowser/#/R-SSC-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Sus scrofa 52255 R-XTR-2424243 https://reactome.org/PathwayBrowser/#/R-XTR-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Xenopus tropicalis 52283 R-MTU-879281 https://reactome.org/PathwayBrowser/#/R-MTU-879281 mycothiol is cleaved to acetylcysteine and glucosaminylinositol TAS Mycobacterium tuberculosis 52283 R-MTU-879311 https://reactome.org/PathwayBrowser/#/R-MTU-879311 mycothiol S-conjugate is cleaved into mercapturic acid and GlcN-Ins TAS Mycobacterium tuberculosis 52283 R-MTU-879319 https://reactome.org/PathwayBrowser/#/R-MTU-879319 glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol TAS Mycobacterium tuberculosis 52283 R-MTU-879327 https://reactome.org/PathwayBrowser/#/R-MTU-879327 acetylglucosamine-inositol is deacetylated by Mca TAS Mycobacterium tuberculosis 52285 R-MTU-879248 https://reactome.org/PathwayBrowser/#/R-MTU-879248 desacetylmycothiol is acetylated to mycothiol using acetyl-CoA TAS Mycobacterium tuberculosis 52285 R-MTU-879319 https://reactome.org/PathwayBrowser/#/R-MTU-879319 glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol TAS Mycobacterium tuberculosis 52288 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 52288 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 52288 R-BTA-417820 https://reactome.org/PathwayBrowser/#/R-BTA-417820 P2Y9 receptor can bind to LPA IEA Bos taurus 52288 R-BTA-417842 https://reactome.org/PathwayBrowser/#/R-BTA-417842 P2Y10 receptor can bind to LPA IEA Bos taurus 52288 R-BTA-417890 https://reactome.org/PathwayBrowser/#/R-BTA-417890 P2Y5 receptor can bind to LPA IEA Bos taurus 52288 R-BTA-419389 https://reactome.org/PathwayBrowser/#/R-BTA-419389 LPA-binding receptors bind LPA IEA Bos taurus 52288 R-BTA-5696074 https://reactome.org/PathwayBrowser/#/R-BTA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Bos taurus 52288 R-BTA-6797630 https://reactome.org/PathwayBrowser/#/R-BTA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Bos taurus 52288 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 52288 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 52288 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 52288 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 52288 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 52288 R-CEL-417820 https://reactome.org/PathwayBrowser/#/R-CEL-417820 P2Y9 receptor can bind to LPA IEA Caenorhabditis elegans 52288 R-CEL-417842 https://reactome.org/PathwayBrowser/#/R-CEL-417842 P2Y10 receptor can bind to LPA IEA Caenorhabditis elegans 52288 R-CEL-417890 https://reactome.org/PathwayBrowser/#/R-CEL-417890 P2Y5 receptor can bind to LPA IEA Caenorhabditis elegans 52288 R-CEL-5696074 https://reactome.org/PathwayBrowser/#/R-CEL-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Caenorhabditis elegans 52288 R-CEL-6797630 https://reactome.org/PathwayBrowser/#/R-CEL-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Caenorhabditis elegans 52288 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 52288 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 52288 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 52288 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 52288 R-CFA-417820 https://reactome.org/PathwayBrowser/#/R-CFA-417820 P2Y9 receptor can bind to LPA IEA Canis familiaris 52288 R-CFA-417842 https://reactome.org/PathwayBrowser/#/R-CFA-417842 P2Y10 receptor can bind to LPA IEA Canis familiaris 52288 R-CFA-417890 https://reactome.org/PathwayBrowser/#/R-CFA-417890 P2Y5 receptor can bind to LPA IEA Canis familiaris 52288 R-CFA-419389 https://reactome.org/PathwayBrowser/#/R-CFA-419389 LPA-binding receptors bind LPA IEA Canis familiaris 52288 R-CFA-5696074 https://reactome.org/PathwayBrowser/#/R-CFA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Canis familiaris 52288 R-CFA-6797630 https://reactome.org/PathwayBrowser/#/R-CFA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Canis familiaris 52288 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 52288 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 52288 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 52288 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 52288 R-DDI-5696074 https://reactome.org/PathwayBrowser/#/R-DDI-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Dictyostelium discoideum 52288 R-DDI-6797630 https://reactome.org/PathwayBrowser/#/R-DDI-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Dictyostelium discoideum 52288 R-DME-5696074 https://reactome.org/PathwayBrowser/#/R-DME-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Drosophila melanogaster 52288 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 52288 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 52288 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 52288 R-DRE-417820 https://reactome.org/PathwayBrowser/#/R-DRE-417820 P2Y9 receptor can bind to LPA IEA Danio rerio 52288 R-DRE-417842 https://reactome.org/PathwayBrowser/#/R-DRE-417842 P2Y10 receptor can bind to LPA IEA Danio rerio 52288 R-DRE-417890 https://reactome.org/PathwayBrowser/#/R-DRE-417890 P2Y5 receptor can bind to LPA IEA Danio rerio 52288 R-DRE-419389 https://reactome.org/PathwayBrowser/#/R-DRE-419389 LPA-binding receptors bind LPA IEA Danio rerio 52288 R-DRE-5696074 https://reactome.org/PathwayBrowser/#/R-DRE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Danio rerio 52288 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 52288 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 52288 R-GGA-417820 https://reactome.org/PathwayBrowser/#/R-GGA-417820 P2Y9 receptor can bind to LPA IEA Gallus gallus 52288 R-GGA-417842 https://reactome.org/PathwayBrowser/#/R-GGA-417842 P2Y10 receptor can bind to LPA IEA Gallus gallus 52288 R-GGA-419389 https://reactome.org/PathwayBrowser/#/R-GGA-419389 LPA-binding receptors bind LPA IEA Gallus gallus 52288 R-GGA-5696074 https://reactome.org/PathwayBrowser/#/R-GGA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Gallus gallus 52288 R-GGA-6797630 https://reactome.org/PathwayBrowser/#/R-GGA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Gallus gallus 52288 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 52288 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 52288 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 52288 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 52288 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 52288 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 52288 R-HSA-417820 https://reactome.org/PathwayBrowser/#/R-HSA-417820 P2Y9 receptor can bind to LPA TAS Homo sapiens 52288 R-HSA-417842 https://reactome.org/PathwayBrowser/#/R-HSA-417842 P2Y10 receptor can bind to LPA TAS Homo sapiens 52288 R-HSA-417890 https://reactome.org/PathwayBrowser/#/R-HSA-417890 P2Y5 receptor can bind to LPA TAS Homo sapiens 52288 R-HSA-419389 https://reactome.org/PathwayBrowser/#/R-HSA-419389 LPA-binding receptors bind LPA TAS Homo sapiens 52288 R-HSA-5696074 https://reactome.org/PathwayBrowser/#/R-HSA-5696074 AGK:Mg2+ phosphorylates MAG, DAG TAS Homo sapiens 52288 R-HSA-6797630 https://reactome.org/PathwayBrowser/#/R-HSA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA TAS Homo sapiens 52288 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 52288 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 52288 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 52288 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 52288 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 52288 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 52288 R-MMU-417820 https://reactome.org/PathwayBrowser/#/R-MMU-417820 P2Y9 receptor can bind to LPA IEA Mus musculus 52288 R-MMU-417842 https://reactome.org/PathwayBrowser/#/R-MMU-417842 P2Y10 receptor can bind to LPA IEA Mus musculus 52288 R-MMU-417890 https://reactome.org/PathwayBrowser/#/R-MMU-417890 P2Y5 receptor can bind to LPA IEA Mus musculus 52288 R-MMU-419389 https://reactome.org/PathwayBrowser/#/R-MMU-419389 LPA-binding receptors bind LPA IEA Mus musculus 52288 R-MMU-5696074 https://reactome.org/PathwayBrowser/#/R-MMU-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Mus musculus 52288 R-MMU-6797630 https://reactome.org/PathwayBrowser/#/R-MMU-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Mus musculus 52288 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 52288 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 52288 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 52288 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 52288 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 52288 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 52288 R-RNO-417820 https://reactome.org/PathwayBrowser/#/R-RNO-417820 P2Y9 receptor can bind to LPA IEA Rattus norvegicus 52288 R-RNO-417842 https://reactome.org/PathwayBrowser/#/R-RNO-417842 P2Y10 receptor can bind to LPA IEA Rattus norvegicus 52288 R-RNO-417890 https://reactome.org/PathwayBrowser/#/R-RNO-417890 P2Y5 receptor can bind to LPA IEA Rattus norvegicus 52288 R-RNO-419389 https://reactome.org/PathwayBrowser/#/R-RNO-419389 LPA-binding receptors bind LPA IEA Rattus norvegicus 52288 R-RNO-5696074 https://reactome.org/PathwayBrowser/#/R-RNO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Rattus norvegicus 52288 R-RNO-6797630 https://reactome.org/PathwayBrowser/#/R-RNO-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Rattus norvegicus 52288 R-SCE-5696074 https://reactome.org/PathwayBrowser/#/R-SCE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Saccharomyces cerevisiae 52288 R-SCE-6797630 https://reactome.org/PathwayBrowser/#/R-SCE-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Saccharomyces cerevisiae 52288 R-SPO-5696074 https://reactome.org/PathwayBrowser/#/R-SPO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Schizosaccharomyces pombe 52288 R-SPO-6797630 https://reactome.org/PathwayBrowser/#/R-SPO-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Schizosaccharomyces pombe 52288 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 52288 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 52288 R-SSC-417820 https://reactome.org/PathwayBrowser/#/R-SSC-417820 P2Y9 receptor can bind to LPA IEA Sus scrofa 52288 R-SSC-417842 https://reactome.org/PathwayBrowser/#/R-SSC-417842 P2Y10 receptor can bind to LPA IEA Sus scrofa 52288 R-SSC-417890 https://reactome.org/PathwayBrowser/#/R-SSC-417890 P2Y5 receptor can bind to LPA IEA Sus scrofa 52288 R-SSC-419389 https://reactome.org/PathwayBrowser/#/R-SSC-419389 LPA-binding receptors bind LPA IEA Sus scrofa 52288 R-SSC-5696074 https://reactome.org/PathwayBrowser/#/R-SSC-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Sus scrofa 52288 R-SSC-6797630 https://reactome.org/PathwayBrowser/#/R-SSC-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Sus scrofa 52288 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 52288 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 52288 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 52288 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 52288 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 52288 R-XTR-417820 https://reactome.org/PathwayBrowser/#/R-XTR-417820 P2Y9 receptor can bind to LPA IEA Xenopus tropicalis 52288 R-XTR-417842 https://reactome.org/PathwayBrowser/#/R-XTR-417842 P2Y10 receptor can bind to LPA IEA Xenopus tropicalis 52288 R-XTR-417890 https://reactome.org/PathwayBrowser/#/R-XTR-417890 P2Y5 receptor can bind to LPA IEA Xenopus tropicalis 52288 R-XTR-419389 https://reactome.org/PathwayBrowser/#/R-XTR-419389 LPA-binding receptors bind LPA IEA Xenopus tropicalis 52288 R-XTR-5696074 https://reactome.org/PathwayBrowser/#/R-XTR-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Xenopus tropicalis 52288 R-XTR-6797630 https://reactome.org/PathwayBrowser/#/R-XTR-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Xenopus tropicalis 52288 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 52288 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 52288 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 52288 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 52289 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 52386 R-BTA-194632 https://reactome.org/PathwayBrowser/#/R-BTA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Bos taurus 52386 R-BTA-194718 https://reactome.org/PathwayBrowser/#/R-BTA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Bos taurus 52386 R-CEL-194718 https://reactome.org/PathwayBrowser/#/R-CEL-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Caenorhabditis elegans 52386 R-CFA-194632 https://reactome.org/PathwayBrowser/#/R-CFA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Canis familiaris 52386 R-CFA-194718 https://reactome.org/PathwayBrowser/#/R-CFA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Canis familiaris 52386 R-DDI-194718 https://reactome.org/PathwayBrowser/#/R-DDI-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Dictyostelium discoideum 52386 R-DRE-194632 https://reactome.org/PathwayBrowser/#/R-DRE-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Danio rerio 52386 R-DRE-194718 https://reactome.org/PathwayBrowser/#/R-DRE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Danio rerio 52386 R-GGA-194632 https://reactome.org/PathwayBrowser/#/R-GGA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Gallus gallus 52386 R-GGA-194718 https://reactome.org/PathwayBrowser/#/R-GGA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Gallus gallus 52386 R-HSA-194632 https://reactome.org/PathwayBrowser/#/R-HSA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) TAS Homo sapiens 52386 R-HSA-194718 https://reactome.org/PathwayBrowser/#/R-HSA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) TAS Homo sapiens 52386 R-MMU-194632 https://reactome.org/PathwayBrowser/#/R-MMU-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Mus musculus 52386 R-MMU-194718 https://reactome.org/PathwayBrowser/#/R-MMU-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Mus musculus 52386 R-RNO-194632 https://reactome.org/PathwayBrowser/#/R-RNO-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Rattus norvegicus 52386 R-RNO-194718 https://reactome.org/PathwayBrowser/#/R-RNO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Rattus norvegicus 52386 R-SCE-194718 https://reactome.org/PathwayBrowser/#/R-SCE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Saccharomyces cerevisiae 52386 R-SPO-194718 https://reactome.org/PathwayBrowser/#/R-SPO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Schizosaccharomyces pombe 52386 R-SSC-194632 https://reactome.org/PathwayBrowser/#/R-SSC-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Sus scrofa 52386 R-SSC-194718 https://reactome.org/PathwayBrowser/#/R-SSC-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Sus scrofa 52392 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 52392 R-BTA-419426 https://reactome.org/PathwayBrowser/#/R-BTA-419426 Cannabinoid receptors can bind cannabinoids IEA Bos taurus 52392 R-BTA-426032 https://reactome.org/PathwayBrowser/#/R-BTA-426032 DAG is metabolized by DAGL to 2-AG IEA Bos taurus 52392 R-BTA-426043 https://reactome.org/PathwayBrowser/#/R-BTA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Bos taurus 52392 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 52392 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 52392 R-CEL-426032 https://reactome.org/PathwayBrowser/#/R-CEL-426032 DAG is metabolized by DAGL to 2-AG IEA Caenorhabditis elegans 52392 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 52392 R-CFA-419426 https://reactome.org/PathwayBrowser/#/R-CFA-419426 Cannabinoid receptors can bind cannabinoids IEA Canis familiaris 52392 R-CFA-426032 https://reactome.org/PathwayBrowser/#/R-CFA-426032 DAG is metabolized by DAGL to 2-AG IEA Canis familiaris 52392 R-CFA-426043 https://reactome.org/PathwayBrowser/#/R-CFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Canis familiaris 52392 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 52392 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 52392 R-DDI-426032 https://reactome.org/PathwayBrowser/#/R-DDI-426032 DAG is metabolized by DAGL to 2-AG IEA Dictyostelium discoideum 52392 R-DDI-426043 https://reactome.org/PathwayBrowser/#/R-DDI-426043 2-AG hydrolysis to arachidonate by MAGL IEA Dictyostelium discoideum 52392 R-DME-426032 https://reactome.org/PathwayBrowser/#/R-DME-426032 DAG is metabolized by DAGL to 2-AG IEA Drosophila melanogaster 52392 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 52392 R-DRE-419426 https://reactome.org/PathwayBrowser/#/R-DRE-419426 Cannabinoid receptors can bind cannabinoids IEA Danio rerio 52392 R-DRE-426032 https://reactome.org/PathwayBrowser/#/R-DRE-426032 DAG is metabolized by DAGL to 2-AG IEA Danio rerio 52392 R-DRE-426043 https://reactome.org/PathwayBrowser/#/R-DRE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Danio rerio 52392 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 52392 R-GGA-419426 https://reactome.org/PathwayBrowser/#/R-GGA-419426 Cannabinoid receptors can bind cannabinoids IEA Gallus gallus 52392 R-GGA-426032 https://reactome.org/PathwayBrowser/#/R-GGA-426032 DAG is metabolized by DAGL to 2-AG IEA Gallus gallus 52392 R-GGA-426043 https://reactome.org/PathwayBrowser/#/R-GGA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Gallus gallus 52392 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 52392 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 52392 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 52392 R-HSA-419426 https://reactome.org/PathwayBrowser/#/R-HSA-419426 Cannabinoid receptors can bind cannabinoids TAS Homo sapiens 52392 R-HSA-426032 https://reactome.org/PathwayBrowser/#/R-HSA-426032 DAG is metabolized by DAGL to 2-AG TAS Homo sapiens 52392 R-HSA-426043 https://reactome.org/PathwayBrowser/#/R-HSA-426043 2-AG hydrolysis to arachidonate by MAGL TAS Homo sapiens 52392 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 52392 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 52392 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 52392 R-MMU-419426 https://reactome.org/PathwayBrowser/#/R-MMU-419426 Cannabinoid receptors can bind cannabinoids IEA Mus musculus 52392 R-MMU-426032 https://reactome.org/PathwayBrowser/#/R-MMU-426032 DAG is metabolized by DAGL to 2-AG IEA Mus musculus 52392 R-MMU-426043 https://reactome.org/PathwayBrowser/#/R-MMU-426043 2-AG hydrolysis to arachidonate by MAGL IEA Mus musculus 52392 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 52392 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 52392 R-PFA-426043 https://reactome.org/PathwayBrowser/#/R-PFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Plasmodium falciparum 52392 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 52392 R-RNO-419426 https://reactome.org/PathwayBrowser/#/R-RNO-419426 Cannabinoid receptors can bind cannabinoids IEA Rattus norvegicus 52392 R-RNO-426032 https://reactome.org/PathwayBrowser/#/R-RNO-426032 DAG is metabolized by DAGL to 2-AG IEA Rattus norvegicus 52392 R-RNO-426043 https://reactome.org/PathwayBrowser/#/R-RNO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Rattus norvegicus 52392 R-SCE-426043 https://reactome.org/PathwayBrowser/#/R-SCE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Saccharomyces cerevisiae 52392 R-SPO-426043 https://reactome.org/PathwayBrowser/#/R-SPO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Schizosaccharomyces pombe 52392 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 52392 R-SSC-419426 https://reactome.org/PathwayBrowser/#/R-SSC-419426 Cannabinoid receptors can bind cannabinoids IEA Sus scrofa 52392 R-SSC-426032 https://reactome.org/PathwayBrowser/#/R-SSC-426032 DAG is metabolized by DAGL to 2-AG IEA Sus scrofa 52392 R-SSC-426043 https://reactome.org/PathwayBrowser/#/R-SSC-426043 2-AG hydrolysis to arachidonate by MAGL IEA Sus scrofa 52392 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 52392 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 52392 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 52392 R-XTR-419426 https://reactome.org/PathwayBrowser/#/R-XTR-419426 Cannabinoid receptors can bind cannabinoids IEA Xenopus tropicalis 52392 R-XTR-426032 https://reactome.org/PathwayBrowser/#/R-XTR-426032 DAG is metabolized by DAGL to 2-AG IEA Xenopus tropicalis 52392 R-XTR-426043 https://reactome.org/PathwayBrowser/#/R-XTR-426043 2-AG hydrolysis to arachidonate by MAGL IEA Xenopus tropicalis 52392 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 52392 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 52442 R-MTU-879274 https://reactome.org/PathwayBrowser/#/R-MTU-879274 acetylglucosamine-inositol-phosphate is dephosphorylated TAS Mycobacterium tuberculosis 52442 R-MTU-879327 https://reactome.org/PathwayBrowser/#/R-MTU-879327 acetylglucosamine-inositol is deacetylated by Mca TAS Mycobacterium tuberculosis 52443 R-MTU-879274 https://reactome.org/PathwayBrowser/#/R-MTU-879274 acetylglucosamine-inositol-phosphate is dephosphorylated TAS Mycobacterium tuberculosis 52443 R-MTU-879298 https://reactome.org/PathwayBrowser/#/R-MTU-879298 acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate TAS Mycobacterium tuberculosis 52449 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 52449 R-BTA-391905 https://reactome.org/PathwayBrowser/#/R-BTA-391905 Oxoeicosanoid receptor can bind oxoeicosanoid IEA Bos taurus 52449 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 52449 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 52449 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 52449 R-CFA-391905 https://reactome.org/PathwayBrowser/#/R-CFA-391905 Oxoeicosanoid receptor can bind oxoeicosanoid IEA Canis familiaris 52449 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 52449 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 52449 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 52449 R-DRE-391905 https://reactome.org/PathwayBrowser/#/R-DRE-391905 Oxoeicosanoid receptor can bind oxoeicosanoid IEA Danio rerio 52449 R-HSA-2161776 https://reactome.org/PathwayBrowser/#/R-HSA-2161776 5S-HETE is oxidised to 5-oxoETE by 5-HEDH TAS Homo sapiens 52449 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 52449 R-HSA-391905 https://reactome.org/PathwayBrowser/#/R-HSA-391905 Oxoeicosanoid receptor can bind oxoeicosanoid TAS Homo sapiens 52449 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 52449 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 52450 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 52450 R-BTA-419351 https://reactome.org/PathwayBrowser/#/R-BTA-419351 PAF receptor binds platelet activating factor IEA Bos taurus 52450 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 52450 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 52450 R-BTA-8869206 https://reactome.org/PathwayBrowser/#/R-BTA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Bos taurus 52450 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 52450 R-CEL-8869206 https://reactome.org/PathwayBrowser/#/R-CEL-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Caenorhabditis elegans 52450 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 52450 R-CFA-419351 https://reactome.org/PathwayBrowser/#/R-CFA-419351 PAF receptor binds platelet activating factor IEA Canis familiaris 52450 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 52450 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 52450 R-CFA-8869206 https://reactome.org/PathwayBrowser/#/R-CFA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Canis familiaris 52450 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 52450 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 52450 R-DRE-419351 https://reactome.org/PathwayBrowser/#/R-DRE-419351 PAF receptor binds platelet activating factor IEA Danio rerio 52450 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 52450 R-GGA-419351 https://reactome.org/PathwayBrowser/#/R-GGA-419351 PAF receptor binds platelet activating factor IEA Gallus gallus 52450 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 52450 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 52450 R-GGA-8869206 https://reactome.org/PathwayBrowser/#/R-GGA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Gallus gallus 52450 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 52450 R-HSA-419351 https://reactome.org/PathwayBrowser/#/R-HSA-419351 PAF receptor binds platelet activating factor TAS Homo sapiens 52450 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 52450 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 52450 R-HSA-8869206 https://reactome.org/PathwayBrowser/#/R-HSA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate TAS Homo sapiens 52450 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 52450 R-MMU-419351 https://reactome.org/PathwayBrowser/#/R-MMU-419351 PAF receptor binds platelet activating factor IEA Mus musculus 52450 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 52450 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 52450 R-MMU-8869206 https://reactome.org/PathwayBrowser/#/R-MMU-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Mus musculus 52450 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 52450 R-RNO-419351 https://reactome.org/PathwayBrowser/#/R-RNO-419351 PAF receptor binds platelet activating factor IEA Rattus norvegicus 52450 R-RNO-8869206 https://reactome.org/PathwayBrowser/#/R-RNO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Rattus norvegicus 52450 R-SPO-8869206 https://reactome.org/PathwayBrowser/#/R-SPO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Schizosaccharomyces pombe 52450 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 52450 R-SSC-419351 https://reactome.org/PathwayBrowser/#/R-SSC-419351 PAF receptor binds platelet activating factor IEA Sus scrofa 52450 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 52450 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 52450 R-SSC-8869206 https://reactome.org/PathwayBrowser/#/R-SSC-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Sus scrofa 52450 R-XTR-419351 https://reactome.org/PathwayBrowser/#/R-XTR-419351 PAF receptor binds platelet activating factor IEA Xenopus tropicalis 52450 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 52450 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 52450 R-XTR-8869206 https://reactome.org/PathwayBrowser/#/R-XTR-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Xenopus tropicalis 52571 R-BTA-5694583 https://reactome.org/PathwayBrowser/#/R-BTA-5694583 ABHD4 hydrolyses NAPE IEA Bos taurus 52571 R-CEL-5694583 https://reactome.org/PathwayBrowser/#/R-CEL-5694583 ABHD4 hydrolyses NAPE IEA Caenorhabditis elegans 52571 R-CFA-5694583 https://reactome.org/PathwayBrowser/#/R-CFA-5694583 ABHD4 hydrolyses NAPE IEA Canis familiaris 52571 R-DME-5694583 https://reactome.org/PathwayBrowser/#/R-DME-5694583 ABHD4 hydrolyses NAPE IEA Drosophila melanogaster 52571 R-HSA-5694583 https://reactome.org/PathwayBrowser/#/R-HSA-5694583 ABHD4 hydrolyses NAPE TAS Homo sapiens 52571 R-MMU-5694583 https://reactome.org/PathwayBrowser/#/R-MMU-5694583 ABHD4 hydrolyses NAPE IEA Mus musculus 52571 R-RNO-5694583 https://reactome.org/PathwayBrowser/#/R-RNO-5694583 ABHD4 hydrolyses NAPE IEA Rattus norvegicus 52571 R-SCE-5694583 https://reactome.org/PathwayBrowser/#/R-SCE-5694583 ABHD4 hydrolyses NAPE IEA Saccharomyces cerevisiae 52571 R-SPO-5694583 https://reactome.org/PathwayBrowser/#/R-SPO-5694583 ABHD4 hydrolyses NAPE IEA Schizosaccharomyces pombe 52571 R-SSC-5694583 https://reactome.org/PathwayBrowser/#/R-SSC-5694583 ABHD4 hydrolyses NAPE IEA Sus scrofa 52571 R-XTR-5694583 https://reactome.org/PathwayBrowser/#/R-XTR-5694583 ABHD4 hydrolyses NAPE IEA Xenopus tropicalis 52572 R-BTA-162683 https://reactome.org/PathwayBrowser/#/R-BTA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Bos taurus 52572 R-CEL-162683 https://reactome.org/PathwayBrowser/#/R-CEL-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Caenorhabditis elegans 52572 R-CFA-162683 https://reactome.org/PathwayBrowser/#/R-CFA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Canis familiaris 52572 R-CFA-162830 https://reactome.org/PathwayBrowser/#/R-CFA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 52572 R-DDI-162683 https://reactome.org/PathwayBrowser/#/R-DDI-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Dictyostelium discoideum 52572 R-DDI-162830 https://reactome.org/PathwayBrowser/#/R-DDI-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 52572 R-DME-162683 https://reactome.org/PathwayBrowser/#/R-DME-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Drosophila melanogaster 52572 R-DME-162830 https://reactome.org/PathwayBrowser/#/R-DME-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 52572 R-GGA-162683 https://reactome.org/PathwayBrowser/#/R-GGA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Gallus gallus 52572 R-GGA-162830 https://reactome.org/PathwayBrowser/#/R-GGA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Gallus gallus 52572 R-HSA-162683 https://reactome.org/PathwayBrowser/#/R-HSA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH TAS Homo sapiens 52572 R-HSA-162830 https://reactome.org/PathwayBrowser/#/R-HSA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 52572 R-HSA-162840 https://reactome.org/PathwayBrowser/#/R-HSA-162840 Reorientation of glucosaminyl-acyl-PI in the endoplasmic reticulum membrane TAS Homo sapiens 52572 R-MMU-162683 https://reactome.org/PathwayBrowser/#/R-MMU-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Mus musculus 52572 R-MMU-162830 https://reactome.org/PathwayBrowser/#/R-MMU-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 52572 R-PFA-162683 https://reactome.org/PathwayBrowser/#/R-PFA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Plasmodium falciparum 52572 R-RNO-162683 https://reactome.org/PathwayBrowser/#/R-RNO-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Rattus norvegicus 52572 R-RNO-162830 https://reactome.org/PathwayBrowser/#/R-RNO-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 52572 R-SCE-162683 https://reactome.org/PathwayBrowser/#/R-SCE-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Saccharomyces cerevisiae 52572 R-SPO-162683 https://reactome.org/PathwayBrowser/#/R-SPO-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Schizosaccharomyces pombe 52572 R-SSC-162683 https://reactome.org/PathwayBrowser/#/R-SSC-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Sus scrofa 52572 R-XTR-162683 https://reactome.org/PathwayBrowser/#/R-XTR-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Xenopus tropicalis 52572 R-XTR-162830 https://reactome.org/PathwayBrowser/#/R-XTR-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 52575 R-BTA-5696119 https://reactome.org/PathwayBrowser/#/R-BTA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Bos taurus 52575 R-CEL-5696119 https://reactome.org/PathwayBrowser/#/R-CEL-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Caenorhabditis elegans 52575 R-CFA-5696119 https://reactome.org/PathwayBrowser/#/R-CFA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Canis familiaris 52575 R-DDI-5696119 https://reactome.org/PathwayBrowser/#/R-DDI-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Dictyostelium discoideum 52575 R-DRE-5696119 https://reactome.org/PathwayBrowser/#/R-DRE-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Danio rerio 52575 R-GGA-5696119 https://reactome.org/PathwayBrowser/#/R-GGA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Gallus gallus 52575 R-HSA-5696119 https://reactome.org/PathwayBrowser/#/R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol TAS Homo sapiens 52575 R-MMU-5696119 https://reactome.org/PathwayBrowser/#/R-MMU-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Mus musculus 52575 R-RNO-5696119 https://reactome.org/PathwayBrowser/#/R-RNO-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Rattus norvegicus 52575 R-SSC-5696119 https://reactome.org/PathwayBrowser/#/R-SSC-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Sus scrofa 52575 R-XTR-5696119 https://reactome.org/PathwayBrowser/#/R-XTR-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Xenopus tropicalis 52592 R-HSA-2466764 https://reactome.org/PathwayBrowser/#/R-HSA-2466764 NRPE condenses with atRAL to form A2PE TAS Homo sapiens 52592 R-HSA-2466831 https://reactome.org/PathwayBrowser/#/R-HSA-2466831 A2PE hydrolyses to A2E TAS Homo sapiens 52603 R-BTA-1482636 https://reactome.org/PathwayBrowser/#/R-BTA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Bos taurus 52603 R-BTA-1482771 https://reactome.org/PathwayBrowser/#/R-BTA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Bos taurus 52603 R-BTA-1482776 https://reactome.org/PathwayBrowser/#/R-BTA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Bos taurus 52603 R-BTA-1602374 https://reactome.org/PathwayBrowser/#/R-BTA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Bos taurus 52603 R-CEL-1482636 https://reactome.org/PathwayBrowser/#/R-CEL-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Caenorhabditis elegans 52603 R-CEL-1482776 https://reactome.org/PathwayBrowser/#/R-CEL-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Caenorhabditis elegans 52603 R-CEL-1602374 https://reactome.org/PathwayBrowser/#/R-CEL-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Caenorhabditis elegans 52603 R-CFA-1482636 https://reactome.org/PathwayBrowser/#/R-CFA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Canis familiaris 52603 R-CFA-1482771 https://reactome.org/PathwayBrowser/#/R-CFA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Canis familiaris 52603 R-CFA-1602374 https://reactome.org/PathwayBrowser/#/R-CFA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Canis familiaris 52603 R-DDI-1482636 https://reactome.org/PathwayBrowser/#/R-DDI-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Dictyostelium discoideum 52603 R-DME-1482636 https://reactome.org/PathwayBrowser/#/R-DME-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Drosophila melanogaster 52603 R-DME-1482776 https://reactome.org/PathwayBrowser/#/R-DME-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Drosophila melanogaster 52603 R-DME-1602374 https://reactome.org/PathwayBrowser/#/R-DME-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Drosophila melanogaster 52603 R-DRE-1482771 https://reactome.org/PathwayBrowser/#/R-DRE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Danio rerio 52603 R-DRE-1602374 https://reactome.org/PathwayBrowser/#/R-DRE-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Danio rerio 52603 R-GGA-1482636 https://reactome.org/PathwayBrowser/#/R-GGA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus 52603 R-GGA-1482771 https://reactome.org/PathwayBrowser/#/R-GGA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Gallus gallus 52603 R-GGA-1482776 https://reactome.org/PathwayBrowser/#/R-GGA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Gallus gallus 52603 R-GGA-1602374 https://reactome.org/PathwayBrowser/#/R-GGA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Gallus gallus 52603 R-HSA-1482636 https://reactome.org/PathwayBrowser/#/R-HSA-1482636 1-acyl LPS is acylated to PS by LPSAT TAS Homo sapiens 52603 R-HSA-1482771 https://reactome.org/PathwayBrowser/#/R-HSA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] TAS Homo sapiens 52603 R-HSA-1482776 https://reactome.org/PathwayBrowser/#/R-HSA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A TAS Homo sapiens 52603 R-HSA-1602374 https://reactome.org/PathwayBrowser/#/R-HSA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] TAS Homo sapiens 52603 R-MMU-1482636 https://reactome.org/PathwayBrowser/#/R-MMU-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Mus musculus 52603 R-MMU-1482771 https://reactome.org/PathwayBrowser/#/R-MMU-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Mus musculus 52603 R-MMU-1482776 https://reactome.org/PathwayBrowser/#/R-MMU-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Mus musculus 52603 R-MMU-1602374 https://reactome.org/PathwayBrowser/#/R-MMU-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Mus musculus 52603 R-PFA-1482636 https://reactome.org/PathwayBrowser/#/R-PFA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Plasmodium falciparum 52603 R-RNO-1482636 https://reactome.org/PathwayBrowser/#/R-RNO-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Rattus norvegicus 52603 R-RNO-1482771 https://reactome.org/PathwayBrowser/#/R-RNO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Rattus norvegicus 52603 R-RNO-1482776 https://reactome.org/PathwayBrowser/#/R-RNO-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Rattus norvegicus 52603 R-RNO-1602374 https://reactome.org/PathwayBrowser/#/R-RNO-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Rattus norvegicus 52603 R-SCE-1482636 https://reactome.org/PathwayBrowser/#/R-SCE-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Saccharomyces cerevisiae 52603 R-SCE-1482771 https://reactome.org/PathwayBrowser/#/R-SCE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Saccharomyces cerevisiae 52603 R-SPO-1482636 https://reactome.org/PathwayBrowser/#/R-SPO-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Schizosaccharomyces pombe 52603 R-SPO-1482771 https://reactome.org/PathwayBrowser/#/R-SPO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Schizosaccharomyces pombe 52603 R-SSC-1482636 https://reactome.org/PathwayBrowser/#/R-SSC-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa 52603 R-SSC-1482771 https://reactome.org/PathwayBrowser/#/R-SSC-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Sus scrofa 52603 R-SSC-1482776 https://reactome.org/PathwayBrowser/#/R-SSC-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Sus scrofa 52603 R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa 52603 R-XTR-1482636 https://reactome.org/PathwayBrowser/#/R-XTR-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Xenopus tropicalis 52603 R-XTR-1482771 https://reactome.org/PathwayBrowser/#/R-XTR-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Xenopus tropicalis 52603 R-XTR-1482776 https://reactome.org/PathwayBrowser/#/R-XTR-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Xenopus tropicalis 52603 R-XTR-1602374 https://reactome.org/PathwayBrowser/#/R-XTR-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Xenopus tropicalis 52639 R-BTA-1638104 https://reactome.org/PathwayBrowser/#/R-BTA-1638104 UGCG transfers glucose to ceramide IEA Bos taurus 52639 R-CEL-1638104 https://reactome.org/PathwayBrowser/#/R-CEL-1638104 UGCG transfers glucose to ceramide IEA Caenorhabditis elegans 52639 R-CFA-1638104 https://reactome.org/PathwayBrowser/#/R-CFA-1638104 UGCG transfers glucose to ceramide IEA Canis familiaris 52639 R-DME-1638104 https://reactome.org/PathwayBrowser/#/R-DME-1638104 UGCG transfers glucose to ceramide IEA Drosophila melanogaster 52639 R-DRE-1638104 https://reactome.org/PathwayBrowser/#/R-DRE-1638104 UGCG transfers glucose to ceramide IEA Danio rerio 52639 R-GGA-1638104 https://reactome.org/PathwayBrowser/#/R-GGA-1638104 UGCG transfers glucose to ceramide IEA Gallus gallus 52639 R-HSA-1638104 https://reactome.org/PathwayBrowser/#/R-HSA-1638104 UGCG transfers glucose to ceramide TAS Homo sapiens 52639 R-MMU-1638104 https://reactome.org/PathwayBrowser/#/R-MMU-1638104 UGCG transfers glucose to ceramide IEA Mus musculus 52639 R-RNO-1638104 https://reactome.org/PathwayBrowser/#/R-RNO-1638104 UGCG transfers glucose to ceramide IEA Rattus norvegicus 52639 R-SSC-1638104 https://reactome.org/PathwayBrowser/#/R-SSC-1638104 UGCG transfers glucose to ceramide IEA Sus scrofa 52639 R-XTR-1638104 https://reactome.org/PathwayBrowser/#/R-XTR-1638104 UGCG transfers glucose to ceramide IEA Xenopus tropicalis 528825 R-BTA-8850356 https://reactome.org/PathwayBrowser/#/R-BTA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Bos taurus 528825 R-CFA-8850356 https://reactome.org/PathwayBrowser/#/R-CFA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Canis familiaris 528825 R-GGA-8850356 https://reactome.org/PathwayBrowser/#/R-GGA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Gallus gallus 528825 R-HSA-8850356 https://reactome.org/PathwayBrowser/#/R-HSA-8850356 TCR binds microbial lipid-based antigen via CD1 TAS Homo sapiens 528825 R-MMU-8850356 https://reactome.org/PathwayBrowser/#/R-MMU-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Mus musculus 528825 R-RNO-8850356 https://reactome.org/PathwayBrowser/#/R-RNO-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Rattus norvegicus 528825 R-SSC-8850356 https://reactome.org/PathwayBrowser/#/R-SSC-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Sus scrofa 5292 R-HSA-1218824 https://reactome.org/PathwayBrowser/#/R-HSA-1218824 HSP90 is inactivated by binding to benzaquinoid ansamycins TAS Homo sapiens 52966 R-BTA-390256 https://reactome.org/PathwayBrowser/#/R-BTA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Bos taurus 52966 R-BTA-390393 https://reactome.org/PathwayBrowser/#/R-BTA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Bos taurus 52966 R-CEL-390256 https://reactome.org/PathwayBrowser/#/R-CEL-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Caenorhabditis elegans 52966 R-CEL-390393 https://reactome.org/PathwayBrowser/#/R-CEL-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Caenorhabditis elegans 52966 R-CFA-390256 https://reactome.org/PathwayBrowser/#/R-CFA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Canis familiaris 52966 R-CFA-390393 https://reactome.org/PathwayBrowser/#/R-CFA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Canis familiaris 52966 R-DDI-390256 https://reactome.org/PathwayBrowser/#/R-DDI-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Dictyostelium discoideum 52966 R-DDI-390393 https://reactome.org/PathwayBrowser/#/R-DDI-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Dictyostelium discoideum 52966 R-DME-390256 https://reactome.org/PathwayBrowser/#/R-DME-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Drosophila melanogaster 52966 R-DME-390393 https://reactome.org/PathwayBrowser/#/R-DME-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Drosophila melanogaster 52966 R-DRE-390256 https://reactome.org/PathwayBrowser/#/R-DRE-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Danio rerio 52966 R-GGA-390256 https://reactome.org/PathwayBrowser/#/R-GGA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Gallus gallus 52966 R-HSA-390256 https://reactome.org/PathwayBrowser/#/R-HSA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 TAS Homo sapiens 52966 R-HSA-390393 https://reactome.org/PathwayBrowser/#/R-HSA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA TAS Homo sapiens 52966 R-MMU-390256 https://reactome.org/PathwayBrowser/#/R-MMU-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Mus musculus 52966 R-MMU-390393 https://reactome.org/PathwayBrowser/#/R-MMU-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Mus musculus 52966 R-RNO-390256 https://reactome.org/PathwayBrowser/#/R-RNO-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Rattus norvegicus 52966 R-RNO-390393 https://reactome.org/PathwayBrowser/#/R-RNO-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Rattus norvegicus 52966 R-SCE-390393 https://reactome.org/PathwayBrowser/#/R-SCE-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Saccharomyces cerevisiae 52966 R-SSC-390256 https://reactome.org/PathwayBrowser/#/R-SSC-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Sus scrofa 52966 R-SSC-390393 https://reactome.org/PathwayBrowser/#/R-SSC-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Sus scrofa 52966 R-XTR-390256 https://reactome.org/PathwayBrowser/#/R-XTR-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Xenopus tropicalis 52966 R-XTR-390393 https://reactome.org/PathwayBrowser/#/R-XTR-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Xenopus tropicalis 52975 R-BTA-390252 https://reactome.org/PathwayBrowser/#/R-BTA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Bos taurus 52975 R-BTA-390256 https://reactome.org/PathwayBrowser/#/R-BTA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Bos taurus 52975 R-BTA-6809263 https://reactome.org/PathwayBrowser/#/R-BTA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Bos taurus 52975 R-CEL-390252 https://reactome.org/PathwayBrowser/#/R-CEL-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Caenorhabditis elegans 52975 R-CEL-390256 https://reactome.org/PathwayBrowser/#/R-CEL-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Caenorhabditis elegans 52975 R-CEL-6809263 https://reactome.org/PathwayBrowser/#/R-CEL-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Caenorhabditis elegans 52975 R-CFA-390252 https://reactome.org/PathwayBrowser/#/R-CFA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Canis familiaris 52975 R-CFA-390256 https://reactome.org/PathwayBrowser/#/R-CFA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Canis familiaris 52975 R-CFA-6809263 https://reactome.org/PathwayBrowser/#/R-CFA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Canis familiaris 52975 R-DDI-390252 https://reactome.org/PathwayBrowser/#/R-DDI-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Dictyostelium discoideum 52975 R-DDI-390256 https://reactome.org/PathwayBrowser/#/R-DDI-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Dictyostelium discoideum 52975 R-DME-390252 https://reactome.org/PathwayBrowser/#/R-DME-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Drosophila melanogaster 52975 R-DME-390256 https://reactome.org/PathwayBrowser/#/R-DME-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Drosophila melanogaster 52975 R-DRE-390256 https://reactome.org/PathwayBrowser/#/R-DRE-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Danio rerio 52975 R-DRE-6809263 https://reactome.org/PathwayBrowser/#/R-DRE-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Danio rerio 52975 R-GGA-390252 https://reactome.org/PathwayBrowser/#/R-GGA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Gallus gallus 52975 R-GGA-390256 https://reactome.org/PathwayBrowser/#/R-GGA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Gallus gallus 52975 R-GGA-6809263 https://reactome.org/PathwayBrowser/#/R-GGA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Gallus gallus 52975 R-HSA-390252 https://reactome.org/PathwayBrowser/#/R-HSA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA TAS Homo sapiens 52975 R-HSA-390256 https://reactome.org/PathwayBrowser/#/R-HSA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 TAS Homo sapiens 52975 R-HSA-6809263 https://reactome.org/PathwayBrowser/#/R-HSA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA TAS Homo sapiens 52975 R-MMU-390252 https://reactome.org/PathwayBrowser/#/R-MMU-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Mus musculus 52975 R-MMU-390256 https://reactome.org/PathwayBrowser/#/R-MMU-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Mus musculus 52975 R-MMU-6809263 https://reactome.org/PathwayBrowser/#/R-MMU-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Mus musculus 52975 R-RNO-390252 https://reactome.org/PathwayBrowser/#/R-RNO-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Rattus norvegicus 52975 R-RNO-390256 https://reactome.org/PathwayBrowser/#/R-RNO-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Rattus norvegicus 52975 R-RNO-6809263 https://reactome.org/PathwayBrowser/#/R-RNO-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Rattus norvegicus 52975 R-SSC-390256 https://reactome.org/PathwayBrowser/#/R-SSC-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Sus scrofa 52975 R-SSC-6809263 https://reactome.org/PathwayBrowser/#/R-SSC-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Sus scrofa 52975 R-XTR-390256 https://reactome.org/PathwayBrowser/#/R-XTR-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Xenopus tropicalis 52975 R-XTR-6809263 https://reactome.org/PathwayBrowser/#/R-XTR-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Xenopus tropicalis 53014 R-BTA-168166 https://reactome.org/PathwayBrowser/#/R-BTA-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Bos taurus 53014 R-BTA-2197770 https://reactome.org/PathwayBrowser/#/R-BTA-2197770 STAB1 (FEEL-1) binds ligands IEA Bos taurus 53014 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 53014 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 53014 R-BTA-2247513 https://reactome.org/PathwayBrowser/#/R-BTA-2247513 STAB1:ligand is endocytosed IEA Bos taurus 53014 R-BTA-879411 https://reactome.org/PathwayBrowser/#/R-BTA-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Bos taurus 53014 R-CFA-168166 https://reactome.org/PathwayBrowser/#/R-CFA-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Canis familiaris 53014 R-CFA-2197770 https://reactome.org/PathwayBrowser/#/R-CFA-2197770 STAB1 (FEEL-1) binds ligands IEA Canis familiaris 53014 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 53014 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 53014 R-CFA-2247513 https://reactome.org/PathwayBrowser/#/R-CFA-2247513 STAB1:ligand is endocytosed IEA Canis familiaris 53014 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 53014 R-CFA-879411 https://reactome.org/PathwayBrowser/#/R-CFA-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Canis familiaris 53014 R-DDI-879411 https://reactome.org/PathwayBrowser/#/R-DDI-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Dictyostelium discoideum 53014 R-DRE-2197770 https://reactome.org/PathwayBrowser/#/R-DRE-2197770 STAB1 (FEEL-1) binds ligands IEA Danio rerio 53014 R-DRE-2247513 https://reactome.org/PathwayBrowser/#/R-DRE-2247513 STAB1:ligand is endocytosed IEA Danio rerio 53014 R-GGA-2197770 https://reactome.org/PathwayBrowser/#/R-GGA-2197770 STAB1 (FEEL-1) binds ligands IEA Gallus gallus 53014 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 53014 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 53014 R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus 53014 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 53014 R-HSA-168166 https://reactome.org/PathwayBrowser/#/R-HSA-168166 NF-kappa-B complex is transported from cytosol to nucleus TAS Homo sapiens 53014 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 53014 R-HSA-2197770 https://reactome.org/PathwayBrowser/#/R-HSA-2197770 STAB1 (FEEL-1) binds ligands TAS Homo sapiens 53014 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 53014 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 53014 R-HSA-2247513 https://reactome.org/PathwayBrowser/#/R-HSA-2247513 STAB1:ligand is endocytosed TAS Homo sapiens 53014 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 53014 R-HSA-879358 https://reactome.org/PathwayBrowser/#/R-HSA-879358 AGER-1,2,3 bind AGEs IEA Homo sapiens 53014 R-HSA-879362 https://reactome.org/PathwayBrowser/#/R-HSA-879362 AGER binds ERK1/2 IEA Homo sapiens 53014 R-HSA-879411 https://reactome.org/PathwayBrowser/#/R-HSA-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor TAS Homo sapiens 53014 R-MMU-168166 https://reactome.org/PathwayBrowser/#/R-MMU-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Mus musculus 53014 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 53014 R-MMU-2197770 https://reactome.org/PathwayBrowser/#/R-MMU-2197770 STAB1 (FEEL-1) binds ligands IEA Mus musculus 53014 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 53014 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 53014 R-MMU-2247513 https://reactome.org/PathwayBrowser/#/R-MMU-2247513 STAB1:ligand is endocytosed IEA Mus musculus 53014 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 53014 R-MMU-879411 https://reactome.org/PathwayBrowser/#/R-MMU-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Mus musculus 53014 R-NUL-879372 https://reactome.org/PathwayBrowser/#/R-NUL-879372 Ager-1,2,3 bind AGEs TAS Rattus norvegicus 53014 R-NUL-997411 https://reactome.org/PathwayBrowser/#/R-NUL-997411 AGER binds rat ERK1/2 TAS Homo sapiens 53014 R-RNO-168166 https://reactome.org/PathwayBrowser/#/R-RNO-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Rattus norvegicus 53014 R-RNO-2197770 https://reactome.org/PathwayBrowser/#/R-RNO-2197770 STAB1 (FEEL-1) binds ligands IEA Rattus norvegicus 53014 R-RNO-2247513 https://reactome.org/PathwayBrowser/#/R-RNO-2247513 STAB1:ligand is endocytosed IEA Rattus norvegicus 53014 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 53014 R-RNO-879411 https://reactome.org/PathwayBrowser/#/R-RNO-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Rattus norvegicus 53014 R-SSC-168166 https://reactome.org/PathwayBrowser/#/R-SSC-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Sus scrofa 53014 R-SSC-2197770 https://reactome.org/PathwayBrowser/#/R-SSC-2197770 STAB1 (FEEL-1) binds ligands IEA Sus scrofa 53014 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 53014 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 53014 R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa 53014 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 53014 R-SSC-879411 https://reactome.org/PathwayBrowser/#/R-SSC-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Sus scrofa 53014 R-XTR-879411 https://reactome.org/PathwayBrowser/#/R-XTR-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Xenopus tropicalis 53019 R-HSA-446194 https://reactome.org/PathwayBrowser/#/R-HSA-446194 Addition of a third glucose to the N-glycan precursor by an ALG10 homologue IEA Homo sapiens 53019 R-HSA-446209 https://reactome.org/PathwayBrowser/#/R-HSA-446209 Transfer of N-glycan to the protein TAS Homo sapiens 53019 R-HSA-9694793 https://reactome.org/PathwayBrowser/#/R-HSA-9694793 Spike protein gets N-glycosylated TAS Homo sapiens 53019 R-SCE-449661 https://reactome.org/PathwayBrowser/#/R-SCE-449661 Addition of a third glucose to the N-glycan skeleton by Alg10 TAS Saccharomyces cerevisiae 53020 R-BTA-446189 https://reactome.org/PathwayBrowser/#/R-BTA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Bos taurus 53020 R-CEL-446189 https://reactome.org/PathwayBrowser/#/R-CEL-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Caenorhabditis elegans 53020 R-CFA-446189 https://reactome.org/PathwayBrowser/#/R-CFA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Canis familiaris 53020 R-DDI-446189 https://reactome.org/PathwayBrowser/#/R-DDI-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Dictyostelium discoideum 53020 R-DME-446189 https://reactome.org/PathwayBrowser/#/R-DME-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Drosophila melanogaster 53020 R-DRE-446189 https://reactome.org/PathwayBrowser/#/R-DRE-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Danio rerio 53020 R-GGA-446189 https://reactome.org/PathwayBrowser/#/R-GGA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Gallus gallus 53020 R-HSA-446189 https://reactome.org/PathwayBrowser/#/R-HSA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 TAS Homo sapiens 53020 R-HSA-446194 https://reactome.org/PathwayBrowser/#/R-HSA-446194 Addition of a third glucose to the N-glycan precursor by an ALG10 homologue IEA Homo sapiens 53020 R-MMU-446189 https://reactome.org/PathwayBrowser/#/R-MMU-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Mus musculus 53020 R-RNO-446189 https://reactome.org/PathwayBrowser/#/R-RNO-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Rattus norvegicus 53020 R-SCE-446189 https://reactome.org/PathwayBrowser/#/R-SCE-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Saccharomyces cerevisiae 53020 R-SCE-449661 https://reactome.org/PathwayBrowser/#/R-SCE-449661 Addition of a third glucose to the N-glycan skeleton by Alg10 TAS Saccharomyces cerevisiae 53020 R-SPO-446189 https://reactome.org/PathwayBrowser/#/R-SPO-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Schizosaccharomyces pombe 53020 R-SSC-446189 https://reactome.org/PathwayBrowser/#/R-SSC-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Sus scrofa 53020 R-XTR-446189 https://reactome.org/PathwayBrowser/#/R-XTR-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Xenopus tropicalis 53023 R-BTA-446188 https://reactome.org/PathwayBrowser/#/R-BTA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Bos taurus 53023 R-BTA-446215 https://reactome.org/PathwayBrowser/#/R-BTA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Bos taurus 53023 R-CEL-446188 https://reactome.org/PathwayBrowser/#/R-CEL-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Caenorhabditis elegans 53023 R-CEL-446215 https://reactome.org/PathwayBrowser/#/R-CEL-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Caenorhabditis elegans 53023 R-CFA-446188 https://reactome.org/PathwayBrowser/#/R-CFA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Canis familiaris 53023 R-CFA-446215 https://reactome.org/PathwayBrowser/#/R-CFA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Canis familiaris 53023 R-DDI-446188 https://reactome.org/PathwayBrowser/#/R-DDI-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Dictyostelium discoideum 53023 R-DDI-446215 https://reactome.org/PathwayBrowser/#/R-DDI-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Dictyostelium discoideum 53023 R-DME-446188 https://reactome.org/PathwayBrowser/#/R-DME-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Drosophila melanogaster 53023 R-DME-446215 https://reactome.org/PathwayBrowser/#/R-DME-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Drosophila melanogaster 53023 R-DRE-446188 https://reactome.org/PathwayBrowser/#/R-DRE-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Danio rerio 53023 R-GGA-446188 https://reactome.org/PathwayBrowser/#/R-GGA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Gallus gallus 53023 R-GGA-446215 https://reactome.org/PathwayBrowser/#/R-GGA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Gallus gallus 53023 R-HSA-446188 https://reactome.org/PathwayBrowser/#/R-HSA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 TAS Homo sapiens 53023 R-HSA-446215 https://reactome.org/PathwayBrowser/#/R-HSA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 TAS Homo sapiens 53023 R-HSA-4720478 https://reactome.org/PathwayBrowser/#/R-HSA-4720478 Defective ALG9 does not add the seventh mannose to the N-glycan precursor TAS Homo sapiens 53023 R-HSA-9036021 https://reactome.org/PathwayBrowser/#/R-HSA-9036021 Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)6 (PP-Dol)1 by ALG9 TAS Homo sapiens 53023 R-MMU-446188 https://reactome.org/PathwayBrowser/#/R-MMU-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Mus musculus 53023 R-MMU-446215 https://reactome.org/PathwayBrowser/#/R-MMU-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Mus musculus 53023 R-RNO-446188 https://reactome.org/PathwayBrowser/#/R-RNO-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Rattus norvegicus 53023 R-RNO-446215 https://reactome.org/PathwayBrowser/#/R-RNO-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Rattus norvegicus 53023 R-SCE-446188 https://reactome.org/PathwayBrowser/#/R-SCE-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Saccharomyces cerevisiae 53023 R-SCE-446215 https://reactome.org/PathwayBrowser/#/R-SCE-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Saccharomyces cerevisiae 53023 R-SPO-446188 https://reactome.org/PathwayBrowser/#/R-SPO-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Schizosaccharomyces pombe 53023 R-SPO-446215 https://reactome.org/PathwayBrowser/#/R-SPO-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Schizosaccharomyces pombe 53023 R-SSC-446188 https://reactome.org/PathwayBrowser/#/R-SSC-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Sus scrofa 53023 R-SSC-446215 https://reactome.org/PathwayBrowser/#/R-SSC-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Sus scrofa 53023 R-XTR-446188 https://reactome.org/PathwayBrowser/#/R-XTR-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Xenopus tropicalis 53023 R-XTR-446215 https://reactome.org/PathwayBrowser/#/R-XTR-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Xenopus tropicalis 53030 R-HSA-2317531 https://reactome.org/PathwayBrowser/#/R-HSA-2317531 SREBP1A,1C,2 binds SCAP:INSIG:oxysterol and is retained in the endoplasmic reticulum IEA Homo sapiens 53030 R-NUL-2317528 https://reactome.org/PathwayBrowser/#/R-NUL-2317528 SREBP2 (SREBF2) is retained in the endoplasmic reticulum by SCAP:INSIG2:oxysterol TAS Cricetulus griseus 53056 R-BTA-162798 https://reactome.org/PathwayBrowser/#/R-BTA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Bos taurus 53056 R-CEL-162798 https://reactome.org/PathwayBrowser/#/R-CEL-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Caenorhabditis elegans 53056 R-CFA-162798 https://reactome.org/PathwayBrowser/#/R-CFA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Canis familiaris 53056 R-CFA-162830 https://reactome.org/PathwayBrowser/#/R-CFA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 53056 R-DDI-162798 https://reactome.org/PathwayBrowser/#/R-DDI-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Dictyostelium discoideum 53056 R-DDI-162830 https://reactome.org/PathwayBrowser/#/R-DDI-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 53056 R-DME-162798 https://reactome.org/PathwayBrowser/#/R-DME-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Drosophila melanogaster 53056 R-DME-162830 https://reactome.org/PathwayBrowser/#/R-DME-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 53056 R-DRE-162798 https://reactome.org/PathwayBrowser/#/R-DRE-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Danio rerio 53056 R-GGA-162798 https://reactome.org/PathwayBrowser/#/R-GGA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Gallus gallus 53056 R-GGA-162830 https://reactome.org/PathwayBrowser/#/R-GGA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Gallus gallus 53056 R-HSA-162798 https://reactome.org/PathwayBrowser/#/R-HSA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol TAS Homo sapiens 53056 R-HSA-162830 https://reactome.org/PathwayBrowser/#/R-HSA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 53056 R-MMU-162798 https://reactome.org/PathwayBrowser/#/R-MMU-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Mus musculus 53056 R-MMU-162830 https://reactome.org/PathwayBrowser/#/R-MMU-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 53056 R-RNO-162798 https://reactome.org/PathwayBrowser/#/R-RNO-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Rattus norvegicus 53056 R-RNO-162830 https://reactome.org/PathwayBrowser/#/R-RNO-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 53056 R-SCE-162798 https://reactome.org/PathwayBrowser/#/R-SCE-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Saccharomyces cerevisiae 53056 R-SPO-162798 https://reactome.org/PathwayBrowser/#/R-SPO-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Schizosaccharomyces pombe 53056 R-SSC-162798 https://reactome.org/PathwayBrowser/#/R-SSC-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Sus scrofa 53056 R-XTR-162798 https://reactome.org/PathwayBrowser/#/R-XTR-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Xenopus tropicalis 53056 R-XTR-162830 https://reactome.org/PathwayBrowser/#/R-XTR-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 53058 R-BTA-162821 https://reactome.org/PathwayBrowser/#/R-BTA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Bos taurus 53058 R-BTA-162873 https://reactome.org/PathwayBrowser/#/R-BTA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Bos taurus 53058 R-CEL-162821 https://reactome.org/PathwayBrowser/#/R-CEL-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Caenorhabditis elegans 53058 R-CEL-162873 https://reactome.org/PathwayBrowser/#/R-CEL-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Caenorhabditis elegans 53058 R-CFA-162821 https://reactome.org/PathwayBrowser/#/R-CFA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 53058 R-CFA-162873 https://reactome.org/PathwayBrowser/#/R-CFA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 53058 R-DDI-162821 https://reactome.org/PathwayBrowser/#/R-DDI-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 53058 R-DDI-162873 https://reactome.org/PathwayBrowser/#/R-DDI-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 53058 R-DME-162821 https://reactome.org/PathwayBrowser/#/R-DME-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 53058 R-DME-162873 https://reactome.org/PathwayBrowser/#/R-DME-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 53058 R-DRE-162821 https://reactome.org/PathwayBrowser/#/R-DRE-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Danio rerio 53058 R-GGA-162873 https://reactome.org/PathwayBrowser/#/R-GGA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Gallus gallus 53058 R-HSA-162821 https://reactome.org/PathwayBrowser/#/R-HSA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 53058 R-HSA-162873 https://reactome.org/PathwayBrowser/#/R-HSA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 53058 R-MMU-162821 https://reactome.org/PathwayBrowser/#/R-MMU-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 53058 R-MMU-162873 https://reactome.org/PathwayBrowser/#/R-MMU-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 53058 R-PFA-162821 https://reactome.org/PathwayBrowser/#/R-PFA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Plasmodium falciparum 53058 R-PFA-162873 https://reactome.org/PathwayBrowser/#/R-PFA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Plasmodium falciparum 53058 R-RNO-162821 https://reactome.org/PathwayBrowser/#/R-RNO-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 53058 R-RNO-162873 https://reactome.org/PathwayBrowser/#/R-RNO-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 53058 R-SCE-162821 https://reactome.org/PathwayBrowser/#/R-SCE-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Saccharomyces cerevisiae 53058 R-SCE-162873 https://reactome.org/PathwayBrowser/#/R-SCE-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Saccharomyces cerevisiae 53058 R-SPO-162821 https://reactome.org/PathwayBrowser/#/R-SPO-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Schizosaccharomyces pombe 53058 R-SPO-162873 https://reactome.org/PathwayBrowser/#/R-SPO-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Schizosaccharomyces pombe 53058 R-SSC-162821 https://reactome.org/PathwayBrowser/#/R-SSC-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Sus scrofa 53058 R-SSC-162873 https://reactome.org/PathwayBrowser/#/R-SSC-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Sus scrofa 53058 R-XTR-162821 https://reactome.org/PathwayBrowser/#/R-XTR-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 53058 R-XTR-162873 https://reactome.org/PathwayBrowser/#/R-XTR-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 53059 R-BTA-162797 https://reactome.org/PathwayBrowser/#/R-BTA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Bos taurus 53059 R-BTA-162821 https://reactome.org/PathwayBrowser/#/R-BTA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Bos taurus 53059 R-CEL-162821 https://reactome.org/PathwayBrowser/#/R-CEL-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Caenorhabditis elegans 53059 R-CFA-162797 https://reactome.org/PathwayBrowser/#/R-CFA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Canis familiaris 53059 R-CFA-162821 https://reactome.org/PathwayBrowser/#/R-CFA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 53059 R-DDI-162797 https://reactome.org/PathwayBrowser/#/R-DDI-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Dictyostelium discoideum 53059 R-DDI-162821 https://reactome.org/PathwayBrowser/#/R-DDI-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 53059 R-DME-162797 https://reactome.org/PathwayBrowser/#/R-DME-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Drosophila melanogaster 53059 R-DME-162821 https://reactome.org/PathwayBrowser/#/R-DME-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 53059 R-DRE-162821 https://reactome.org/PathwayBrowser/#/R-DRE-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Danio rerio 53059 R-GGA-162797 https://reactome.org/PathwayBrowser/#/R-GGA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Gallus gallus 53059 R-HSA-162797 https://reactome.org/PathwayBrowser/#/R-HSA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI TAS Homo sapiens 53059 R-HSA-162821 https://reactome.org/PathwayBrowser/#/R-HSA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 53059 R-HSA-163069 https://reactome.org/PathwayBrowser/#/R-HSA-163069 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol IEA Homo sapiens 53059 R-MMU-162797 https://reactome.org/PathwayBrowser/#/R-MMU-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Mus musculus 53059 R-MMU-162821 https://reactome.org/PathwayBrowser/#/R-MMU-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 53059 R-MMU-162863 https://reactome.org/PathwayBrowser/#/R-MMU-162863 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol TAS Mus musculus 53059 R-PFA-162821 https://reactome.org/PathwayBrowser/#/R-PFA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Plasmodium falciparum 53059 R-RNO-162821 https://reactome.org/PathwayBrowser/#/R-RNO-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 53059 R-SCE-162797 https://reactome.org/PathwayBrowser/#/R-SCE-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Saccharomyces cerevisiae 53059 R-SCE-162821 https://reactome.org/PathwayBrowser/#/R-SCE-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Saccharomyces cerevisiae 53059 R-SPO-162797 https://reactome.org/PathwayBrowser/#/R-SPO-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Schizosaccharomyces pombe 53059 R-SPO-162821 https://reactome.org/PathwayBrowser/#/R-SPO-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Schizosaccharomyces pombe 53059 R-SSC-162797 https://reactome.org/PathwayBrowser/#/R-SSC-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Sus scrofa 53059 R-SSC-162821 https://reactome.org/PathwayBrowser/#/R-SSC-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Sus scrofa 53059 R-XTR-162821 https://reactome.org/PathwayBrowser/#/R-XTR-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 53100 R-HSA-6782434 https://reactome.org/PathwayBrowser/#/R-HSA-6782434 THG1L transfers GMP to 5' end of tRNA(His) TAS Homo sapiens 53106 R-HSA-5423656 https://reactome.org/PathwayBrowser/#/R-HSA-5423656 AFXBO hydrolyses non-enzymatically to AFBDHD TAS Homo sapiens 53106 R-HSA-5423694 https://reactome.org/PathwayBrowser/#/R-HSA-5423694 AFBDHD hydrolyses non-enzymatically to AFBDHO TAS Homo sapiens 53107 R-BTA-5423637 https://reactome.org/PathwayBrowser/#/R-BTA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Bos taurus 53107 R-CFA-5423637 https://reactome.org/PathwayBrowser/#/R-CFA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Canis familiaris 53107 R-DRE-5423637 https://reactome.org/PathwayBrowser/#/R-DRE-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Danio rerio 53107 R-GGA-5423637 https://reactome.org/PathwayBrowser/#/R-GGA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Gallus gallus 53107 R-HSA-5423637 https://reactome.org/PathwayBrowser/#/R-HSA-5423637 AKR dimers reduce AFBDHO to AFBDOH TAS Homo sapiens 53107 R-HSA-5423694 https://reactome.org/PathwayBrowser/#/R-HSA-5423694 AFBDHD hydrolyses non-enzymatically to AFBDHO TAS Homo sapiens 53107 R-MMU-5423637 https://reactome.org/PathwayBrowser/#/R-MMU-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Mus musculus 53107 R-RNO-5423637 https://reactome.org/PathwayBrowser/#/R-RNO-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Rattus norvegicus 53107 R-SSC-5423637 https://reactome.org/PathwayBrowser/#/R-SSC-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Sus scrofa 53108 R-BTA-5423637 https://reactome.org/PathwayBrowser/#/R-BTA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Bos taurus 53108 R-CFA-5423637 https://reactome.org/PathwayBrowser/#/R-CFA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Canis familiaris 53108 R-DRE-5423637 https://reactome.org/PathwayBrowser/#/R-DRE-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Danio rerio 53108 R-GGA-5423637 https://reactome.org/PathwayBrowser/#/R-GGA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Gallus gallus 53108 R-HSA-5423637 https://reactome.org/PathwayBrowser/#/R-HSA-5423637 AKR dimers reduce AFBDHO to AFBDOH TAS Homo sapiens 53108 R-MMU-5423637 https://reactome.org/PathwayBrowser/#/R-MMU-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Mus musculus 53108 R-RNO-5423637 https://reactome.org/PathwayBrowser/#/R-RNO-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Rattus norvegicus 53108 R-SSC-5423637 https://reactome.org/PathwayBrowser/#/R-SSC-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Sus scrofa 53152 R-HSA-3238694 https://reactome.org/PathwayBrowser/#/R-HSA-3238694 PORCN palmitoleoylates N-glycosyl WNTs IEA Homo sapiens 53152 R-MMU-3238687 https://reactome.org/PathwayBrowser/#/R-MMU-3238687 PORCN palmitoleoylates WNT3a TAS Mus musculus 53153 R-BTA-5164399 https://reactome.org/PathwayBrowser/#/R-BTA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Bos taurus 53153 R-CEL-5164399 https://reactome.org/PathwayBrowser/#/R-CEL-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Caenorhabditis elegans 53153 R-CFA-5164399 https://reactome.org/PathwayBrowser/#/R-CFA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Canis familiaris 53153 R-DME-5164399 https://reactome.org/PathwayBrowser/#/R-DME-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Drosophila melanogaster 53153 R-DRE-5164399 https://reactome.org/PathwayBrowser/#/R-DRE-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Danio rerio 53153 R-GGA-5164399 https://reactome.org/PathwayBrowser/#/R-GGA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Gallus gallus 53153 R-HSA-5164399 https://reactome.org/PathwayBrowser/#/R-HSA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION TAS Homo sapiens 53153 R-MMU-5164399 https://reactome.org/PathwayBrowser/#/R-MMU-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Mus musculus 53153 R-RNO-5164399 https://reactome.org/PathwayBrowser/#/R-RNO-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Rattus norvegicus 53153 R-SSC-5164399 https://reactome.org/PathwayBrowser/#/R-SSC-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Sus scrofa 53153 R-XTR-5164399 https://reactome.org/PathwayBrowser/#/R-XTR-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Xenopus tropicalis 53170 R-HSA-443778 https://reactome.org/PathwayBrowser/#/R-HSA-443778 Interaction of L1 with Laminin-1 IEA Homo sapiens 53170 R-MMU-443785 https://reactome.org/PathwayBrowser/#/R-MMU-443785 Interaction of L1 with Laminin-1 TAS Mus musculus 53289 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 53289 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 53289 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 53289 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 53289 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 53289 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 53289 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 53289 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 53289 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 53289 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 53289 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 53289 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 53289 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 53289 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 53289 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 5331 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 5331 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 5331 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 5331 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 5331 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 5331 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 5331 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 5331 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 5331 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 53460 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 53460 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 53460 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 53460 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 53460 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 53460 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 53460 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 53460 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 53460 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 53460 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 53460 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 53460 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 53460 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 53460 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 53460 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 53460 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 53460 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 53460 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 53460 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 53460 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 53460 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 53460 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 53460 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 53460 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 53460 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 53460 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 53460 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 53460 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 53460 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 53460 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 53460 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 53460 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 53460 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 53460 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 53460 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 53486 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 53486 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 53486 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 53486 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 53486 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 53486 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 53486 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 53486 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 53486 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 53486 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 53486 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 53486 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 53486 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 53486 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 53486 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 53486 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 53486 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 53486 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 53486 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 53486 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 53486 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 53486 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 53486 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 53486 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 53486 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 53486 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 53486 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 53486 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 53486 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 53486 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 53486 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 53486 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 53486 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 53486 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 53486 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 53487 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 53487 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 53487 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 53487 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 53487 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 53487 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 53487 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 53487 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 53487 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 53487 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 53487 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 53487 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 53487 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 53487 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 53487 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 53487 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 53487 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 53487 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 53487 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 53487 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 53487 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 53487 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 53487 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 53487 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 53487 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 53487 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 53487 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 53487 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 53487 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 53487 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 53487 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 53487 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 53487 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 53487 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 53487 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 53490 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 53490 R-CFA-444527 https://reactome.org/PathwayBrowser/#/R-CFA-444527 FPR is a receptor for formyl peptides IEA Canis familiaris 53490 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 53490 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 53490 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 53490 R-HSA-444527 https://reactome.org/PathwayBrowser/#/R-HSA-444527 FPR is a receptor for formyl peptides TAS Homo sapiens 53490 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 53490 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 53490 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 53490 R-MMU-444527 https://reactome.org/PathwayBrowser/#/R-MMU-444527 FPR is a receptor for formyl peptides IEA Mus musculus 53490 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 53490 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 53490 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 53490 R-RNO-444527 https://reactome.org/PathwayBrowser/#/R-RNO-444527 FPR is a receptor for formyl peptides IEA Rattus norvegicus 53490 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 53490 R-XTR-444527 https://reactome.org/PathwayBrowser/#/R-XTR-444527 FPR is a receptor for formyl peptides IEA Xenopus tropicalis 53490 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 53490 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 53742 R-HSA-446187 https://reactome.org/PathwayBrowser/#/R-HSA-446187 ALG11 transfers the fourth and fifth Man to the N-glycan precursor IEA Homo sapiens 53742 R-HSA-449718 https://reactome.org/PathwayBrowser/#/R-HSA-449718 Addition of a third mannose to the N-glycan precursor by ALG2 IEA Homo sapiens 53742 R-HSA-4551297 https://reactome.org/PathwayBrowser/#/R-HSA-4551297 Defective ALG11 does not transfer Man to the N-glycan precursor TAS Homo sapiens 53742 R-SCE-449324 https://reactome.org/PathwayBrowser/#/R-SCE-449324 Addition of the fourth and fifth mannose to the N-glycan precursor skeleton by Alg11 TAS Saccharomyces cerevisiae 53742 R-SCE-449748 https://reactome.org/PathwayBrowser/#/R-SCE-449748 Addition of a third mannose to the N-glycan precursor by Alg2 TAS Saccharomyces cerevisiae 53766 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 53766 R-BTA-9026967 https://reactome.org/PathwayBrowser/#/R-BTA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Bos taurus 53766 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 53766 R-CFA-9026967 https://reactome.org/PathwayBrowser/#/R-CFA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Canis familiaris 53766 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 53766 R-DME-9026967 https://reactome.org/PathwayBrowser/#/R-DME-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Drosophila melanogaster 53766 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 53766 R-HSA-9026967 https://reactome.org/PathwayBrowser/#/R-HSA-9026967 VKORC1 inhibitors binds VKORC1 dimer TAS Homo sapiens 53766 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 53766 R-MMU-9026967 https://reactome.org/PathwayBrowser/#/R-MMU-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Mus musculus 53766 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 53766 R-RNO-9026967 https://reactome.org/PathwayBrowser/#/R-RNO-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Rattus norvegicus 53766 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 53766 R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa 53766 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 53766 R-XTR-9026967 https://reactome.org/PathwayBrowser/#/R-XTR-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Xenopus tropicalis 5383 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 5383 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 5383 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 5383 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 5383 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 5383 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 5383 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 5383 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 5383 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 5384 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 5384 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 5384 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 5384 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 5384 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 5384 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 5384 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 5384 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 5384 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 5441 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 5441 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 5441 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 5441 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 5441 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 5441 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 5441 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 5441 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 5441 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 545111 R-BTA-5696424 https://reactome.org/PathwayBrowser/#/R-BTA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Bos taurus 545111 R-CEL-5696424 https://reactome.org/PathwayBrowser/#/R-CEL-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Caenorhabditis elegans 545111 R-CFA-5696424 https://reactome.org/PathwayBrowser/#/R-CFA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Canis familiaris 545111 R-DDI-5696424 https://reactome.org/PathwayBrowser/#/R-DDI-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Dictyostelium discoideum 545111 R-DME-5696424 https://reactome.org/PathwayBrowser/#/R-DME-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Drosophila melanogaster 545111 R-DRE-5696424 https://reactome.org/PathwayBrowser/#/R-DRE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Danio rerio 545111 R-GGA-5696424 https://reactome.org/PathwayBrowser/#/R-GGA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Gallus gallus 545111 R-HSA-5696424 https://reactome.org/PathwayBrowser/#/R-HSA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters TAS Homo sapiens 545111 R-MMU-5696424 https://reactome.org/PathwayBrowser/#/R-MMU-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Mus musculus 545111 R-RNO-5696424 https://reactome.org/PathwayBrowser/#/R-RNO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Rattus norvegicus 545111 R-SCE-5696424 https://reactome.org/PathwayBrowser/#/R-SCE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Saccharomyces cerevisiae 545111 R-SPO-5696424 https://reactome.org/PathwayBrowser/#/R-SPO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Schizosaccharomyces pombe 545111 R-XTR-5696424 https://reactome.org/PathwayBrowser/#/R-XTR-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Xenopus tropicalis 545959 R-BTA-379395 https://reactome.org/PathwayBrowser/#/R-BTA-379395 MAOA:FAD deaminates 3MT to HVA IEA Bos taurus 545959 R-BTA-379464 https://reactome.org/PathwayBrowser/#/R-BTA-379464 COMT transfers Met to DOPAC to form HVA IEA Bos taurus 545959 R-CFA-379395 https://reactome.org/PathwayBrowser/#/R-CFA-379395 MAOA:FAD deaminates 3MT to HVA IEA Canis familiaris 545959 R-CFA-379464 https://reactome.org/PathwayBrowser/#/R-CFA-379464 COMT transfers Met to DOPAC to form HVA IEA Canis familiaris 545959 R-DDI-379395 https://reactome.org/PathwayBrowser/#/R-DDI-379395 MAOA:FAD deaminates 3MT to HVA IEA Dictyostelium discoideum 545959 R-DRE-379464 https://reactome.org/PathwayBrowser/#/R-DRE-379464 COMT transfers Met to DOPAC to form HVA IEA Danio rerio 545959 R-GGA-379395 https://reactome.org/PathwayBrowser/#/R-GGA-379395 MAOA:FAD deaminates 3MT to HVA IEA Gallus gallus 545959 R-GGA-379464 https://reactome.org/PathwayBrowser/#/R-GGA-379464 COMT transfers Met to DOPAC to form HVA IEA Gallus gallus 545959 R-HSA-379395 https://reactome.org/PathwayBrowser/#/R-HSA-379395 MAOA:FAD deaminates 3MT to HVA TAS Homo sapiens 545959 R-HSA-379464 https://reactome.org/PathwayBrowser/#/R-HSA-379464 COMT transfers Met to DOPAC to form HVA TAS Homo sapiens 545959 R-MMU-379395 https://reactome.org/PathwayBrowser/#/R-MMU-379395 MAOA:FAD deaminates 3MT to HVA IEA Mus musculus 545959 R-MMU-379464 https://reactome.org/PathwayBrowser/#/R-MMU-379464 COMT transfers Met to DOPAC to form HVA IEA Mus musculus 545959 R-RNO-379395 https://reactome.org/PathwayBrowser/#/R-RNO-379395 MAOA:FAD deaminates 3MT to HVA IEA Rattus norvegicus 545959 R-RNO-379464 https://reactome.org/PathwayBrowser/#/R-RNO-379464 COMT transfers Met to DOPAC to form HVA IEA Rattus norvegicus 545959 R-SPO-379464 https://reactome.org/PathwayBrowser/#/R-SPO-379464 COMT transfers Met to DOPAC to form HVA IEA Schizosaccharomyces pombe 545959 R-SSC-379395 https://reactome.org/PathwayBrowser/#/R-SSC-379395 MAOA:FAD deaminates 3MT to HVA IEA Sus scrofa 545959 R-SSC-379464 https://reactome.org/PathwayBrowser/#/R-SSC-379464 COMT transfers Met to DOPAC to form HVA IEA Sus scrofa 545959 R-XTR-379464 https://reactome.org/PathwayBrowser/#/R-XTR-379464 COMT transfers Met to DOPAC to form HVA IEA Xenopus tropicalis 55376 R-BTA-6789031 https://reactome.org/PathwayBrowser/#/R-BTA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 55376 R-BTA-6789126 https://reactome.org/PathwayBrowser/#/R-BTA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 55376 R-BTA-6789136 https://reactome.org/PathwayBrowser/#/R-BTA-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Bos taurus 55376 R-BTA-8855490 https://reactome.org/PathwayBrowser/#/R-BTA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Bos taurus 55376 R-BTA-8933635 https://reactome.org/PathwayBrowser/#/R-BTA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Bos taurus 55376 R-CEL-6789031 https://reactome.org/PathwayBrowser/#/R-CEL-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 55376 R-CEL-6789126 https://reactome.org/PathwayBrowser/#/R-CEL-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 55376 R-CEL-6789136 https://reactome.org/PathwayBrowser/#/R-CEL-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Caenorhabditis elegans 55376 R-CEL-8855490 https://reactome.org/PathwayBrowser/#/R-CEL-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Caenorhabditis elegans 55376 R-CEL-8933635 https://reactome.org/PathwayBrowser/#/R-CEL-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Caenorhabditis elegans 55376 R-CFA-6789031 https://reactome.org/PathwayBrowser/#/R-CFA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 55376 R-CFA-6789126 https://reactome.org/PathwayBrowser/#/R-CFA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 55376 R-CFA-6789136 https://reactome.org/PathwayBrowser/#/R-CFA-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Canis familiaris 55376 R-CFA-8855490 https://reactome.org/PathwayBrowser/#/R-CFA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Canis familiaris 55376 R-CFA-8933635 https://reactome.org/PathwayBrowser/#/R-CFA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Canis familiaris 55376 R-DDI-6789031 https://reactome.org/PathwayBrowser/#/R-DDI-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 55376 R-DDI-6789126 https://reactome.org/PathwayBrowser/#/R-DDI-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 55376 R-DDI-6789136 https://reactome.org/PathwayBrowser/#/R-DDI-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Dictyostelium discoideum 55376 R-DDI-8855490 https://reactome.org/PathwayBrowser/#/R-DDI-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Dictyostelium discoideum 55376 R-DDI-8933635 https://reactome.org/PathwayBrowser/#/R-DDI-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Dictyostelium discoideum 55376 R-DME-6789031 https://reactome.org/PathwayBrowser/#/R-DME-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 55376 R-DME-6789126 https://reactome.org/PathwayBrowser/#/R-DME-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 55376 R-DME-6789136 https://reactome.org/PathwayBrowser/#/R-DME-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Drosophila melanogaster 55376 R-DME-8855490 https://reactome.org/PathwayBrowser/#/R-DME-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Drosophila melanogaster 55376 R-DME-8933635 https://reactome.org/PathwayBrowser/#/R-DME-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Drosophila melanogaster 55376 R-GGA-6789031 https://reactome.org/PathwayBrowser/#/R-GGA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 55376 R-GGA-6789126 https://reactome.org/PathwayBrowser/#/R-GGA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 55376 R-GGA-6789136 https://reactome.org/PathwayBrowser/#/R-GGA-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Gallus gallus 55376 R-GGA-8855490 https://reactome.org/PathwayBrowser/#/R-GGA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Gallus gallus 55376 R-GGA-8933635 https://reactome.org/PathwayBrowser/#/R-GGA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Gallus gallus 55376 R-HSA-6789031 https://reactome.org/PathwayBrowser/#/R-HSA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 55376 R-HSA-6789126 https://reactome.org/PathwayBrowser/#/R-HSA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 55376 R-HSA-6789136 https://reactome.org/PathwayBrowser/#/R-HSA-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface TAS Homo sapiens 55376 R-HSA-8855490 https://reactome.org/PathwayBrowser/#/R-HSA-8855490 Lactoperoxidase (LPO) produces OSCN- TAS Homo sapiens 55376 R-HSA-8933635 https://reactome.org/PathwayBrowser/#/R-HSA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide TAS Homo sapiens 55376 R-MMU-6789031 https://reactome.org/PathwayBrowser/#/R-MMU-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 55376 R-MMU-6789126 https://reactome.org/PathwayBrowser/#/R-MMU-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 55376 R-MMU-6789136 https://reactome.org/PathwayBrowser/#/R-MMU-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Mus musculus 55376 R-MMU-8855490 https://reactome.org/PathwayBrowser/#/R-MMU-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Mus musculus 55376 R-MMU-8933635 https://reactome.org/PathwayBrowser/#/R-MMU-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Mus musculus 55376 R-RNO-6789031 https://reactome.org/PathwayBrowser/#/R-RNO-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 55376 R-RNO-6789126 https://reactome.org/PathwayBrowser/#/R-RNO-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 55376 R-RNO-6789136 https://reactome.org/PathwayBrowser/#/R-RNO-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Rattus norvegicus 55376 R-RNO-8855490 https://reactome.org/PathwayBrowser/#/R-RNO-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Rattus norvegicus 55376 R-RNO-8933635 https://reactome.org/PathwayBrowser/#/R-RNO-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Rattus norvegicus 55376 R-SSC-6789031 https://reactome.org/PathwayBrowser/#/R-SSC-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 55376 R-SSC-6789126 https://reactome.org/PathwayBrowser/#/R-SSC-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 55376 R-SSC-6789136 https://reactome.org/PathwayBrowser/#/R-SSC-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Sus scrofa 55376 R-SSC-8855490 https://reactome.org/PathwayBrowser/#/R-SSC-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Sus scrofa 55376 R-SSC-8933635 https://reactome.org/PathwayBrowser/#/R-SSC-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Sus scrofa 55424 R-BTA-6789072 https://reactome.org/PathwayBrowser/#/R-BTA-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Bos taurus 55424 R-BTA-6799959 https://reactome.org/PathwayBrowser/#/R-BTA-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Bos taurus 55424 R-BTA-6799977 https://reactome.org/PathwayBrowser/#/R-BTA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Bos taurus 55424 R-BTA-6799981 https://reactome.org/PathwayBrowser/#/R-BTA-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Bos taurus 55424 R-BTA-6801808 https://reactome.org/PathwayBrowser/#/R-BTA-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Bos taurus 55424 R-BTA-6803063 https://reactome.org/PathwayBrowser/#/R-BTA-6803063 RNASEs bind bacterial LPS, PGN IEA Bos taurus 55424 R-BTA-8862300 https://reactome.org/PathwayBrowser/#/R-BTA-8862300 LYZ binds bacterial peptidoglycan IEA Bos taurus 55424 R-BTA-8862320 https://reactome.org/PathwayBrowser/#/R-BTA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Bos taurus 55424 R-CEL-6801808 https://reactome.org/PathwayBrowser/#/R-CEL-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Caenorhabditis elegans 55424 R-CFA-6789072 https://reactome.org/PathwayBrowser/#/R-CFA-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Canis familiaris 55424 R-CFA-6799977 https://reactome.org/PathwayBrowser/#/R-CFA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Canis familiaris 55424 R-CFA-6799981 https://reactome.org/PathwayBrowser/#/R-CFA-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Canis familiaris 55424 R-CFA-6801808 https://reactome.org/PathwayBrowser/#/R-CFA-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Canis familiaris 55424 R-CFA-8862300 https://reactome.org/PathwayBrowser/#/R-CFA-8862300 LYZ binds bacterial peptidoglycan IEA Canis familiaris 55424 R-CFA-8862320 https://reactome.org/PathwayBrowser/#/R-CFA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Canis familiaris 55424 R-DDI-8862300 https://reactome.org/PathwayBrowser/#/R-DDI-8862300 LYZ binds bacterial peptidoglycan IEA Dictyostelium discoideum 55424 R-DDI-8862320 https://reactome.org/PathwayBrowser/#/R-DDI-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Dictyostelium discoideum 55424 R-DME-6789072 https://reactome.org/PathwayBrowser/#/R-DME-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Drosophila melanogaster 55424 R-DME-6799959 https://reactome.org/PathwayBrowser/#/R-DME-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Drosophila melanogaster 55424 R-DME-6799977 https://reactome.org/PathwayBrowser/#/R-DME-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Drosophila melanogaster 55424 R-DME-6799981 https://reactome.org/PathwayBrowser/#/R-DME-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Drosophila melanogaster 55424 R-DME-6801808 https://reactome.org/PathwayBrowser/#/R-DME-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Drosophila melanogaster 55424 R-DME-8862300 https://reactome.org/PathwayBrowser/#/R-DME-8862300 LYZ binds bacterial peptidoglycan IEA Drosophila melanogaster 55424 R-DME-8862320 https://reactome.org/PathwayBrowser/#/R-DME-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Drosophila melanogaster 55424 R-DRE-6789072 https://reactome.org/PathwayBrowser/#/R-DRE-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Danio rerio 55424 R-DRE-6799959 https://reactome.org/PathwayBrowser/#/R-DRE-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Danio rerio 55424 R-DRE-6799977 https://reactome.org/PathwayBrowser/#/R-DRE-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Danio rerio 55424 R-DRE-6799981 https://reactome.org/PathwayBrowser/#/R-DRE-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Danio rerio 55424 R-DRE-6803063 https://reactome.org/PathwayBrowser/#/R-DRE-6803063 RNASEs bind bacterial LPS, PGN IEA Danio rerio 55424 R-DRE-8862300 https://reactome.org/PathwayBrowser/#/R-DRE-8862300 LYZ binds bacterial peptidoglycan IEA Danio rerio 55424 R-DRE-8862320 https://reactome.org/PathwayBrowser/#/R-DRE-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Danio rerio 55424 R-GGA-6799977 https://reactome.org/PathwayBrowser/#/R-GGA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Gallus gallus 55424 R-GGA-6799981 https://reactome.org/PathwayBrowser/#/R-GGA-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Gallus gallus 55424 R-GGA-6803063 https://reactome.org/PathwayBrowser/#/R-GGA-6803063 RNASEs bind bacterial LPS, PGN IEA Gallus gallus 55424 R-GGA-8862300 https://reactome.org/PathwayBrowser/#/R-GGA-8862300 LYZ binds bacterial peptidoglycan IEA Gallus gallus 55424 R-GGA-8862320 https://reactome.org/PathwayBrowser/#/R-GGA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Gallus gallus 55424 R-HSA-6789072 https://reactome.org/PathwayBrowser/#/R-HSA-6789072 PGLYRP1 binds bacterial peptidoglycan TAS Homo sapiens 55424 R-HSA-6789185 https://reactome.org/PathwayBrowser/#/R-HSA-6789185 Chloride ion and N-acyl group react to chloramide TAS Homo sapiens 55424 R-HSA-6789208 https://reactome.org/PathwayBrowser/#/R-HSA-6789208 HOCl-induced glycosaminoglycan fragmentation TAS Homo sapiens 55424 R-HSA-6799959 https://reactome.org/PathwayBrowser/#/R-HSA-6799959 PGLYRP3,4 binds bacterial peptidoglycan TAS Homo sapiens 55424 R-HSA-6799977 https://reactome.org/PathwayBrowser/#/R-HSA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan TAS Homo sapiens 55424 R-HSA-6799981 https://reactome.org/PathwayBrowser/#/R-HSA-6799981 PGLYRP2 binds bacterial peptidoglycan TAS Homo sapiens 55424 R-HSA-6801808 https://reactome.org/PathwayBrowser/#/R-HSA-6801808 REG3A,REG3G binds bacterial peptidoglycan TAS Homo sapiens 55424 R-HSA-6803063 https://reactome.org/PathwayBrowser/#/R-HSA-6803063 RNASEs bind bacterial LPS, PGN TAS Homo sapiens 55424 R-HSA-8862300 https://reactome.org/PathwayBrowser/#/R-HSA-8862300 LYZ binds bacterial peptidoglycan TAS Homo sapiens 55424 R-HSA-8862320 https://reactome.org/PathwayBrowser/#/R-HSA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall TAS Homo sapiens 55424 R-MMU-6789072 https://reactome.org/PathwayBrowser/#/R-MMU-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Mus musculus 55424 R-MMU-6799959 https://reactome.org/PathwayBrowser/#/R-MMU-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Mus musculus 55424 R-MMU-6799977 https://reactome.org/PathwayBrowser/#/R-MMU-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Mus musculus 55424 R-MMU-6799981 https://reactome.org/PathwayBrowser/#/R-MMU-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Mus musculus 55424 R-MMU-6801808 https://reactome.org/PathwayBrowser/#/R-MMU-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Mus musculus 55424 R-MMU-6803063 https://reactome.org/PathwayBrowser/#/R-MMU-6803063 RNASEs bind bacterial LPS, PGN IEA Mus musculus 55424 R-MMU-8862300 https://reactome.org/PathwayBrowser/#/R-MMU-8862300 LYZ binds bacterial peptidoglycan IEA Mus musculus 55424 R-MMU-8862320 https://reactome.org/PathwayBrowser/#/R-MMU-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Mus musculus 55424 R-RNO-6789072 https://reactome.org/PathwayBrowser/#/R-RNO-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Rattus norvegicus 55424 R-RNO-6799959 https://reactome.org/PathwayBrowser/#/R-RNO-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Rattus norvegicus 55424 R-RNO-6799977 https://reactome.org/PathwayBrowser/#/R-RNO-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Rattus norvegicus 55424 R-RNO-6799981 https://reactome.org/PathwayBrowser/#/R-RNO-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Rattus norvegicus 55424 R-RNO-6801808 https://reactome.org/PathwayBrowser/#/R-RNO-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Rattus norvegicus 55424 R-RNO-6803063 https://reactome.org/PathwayBrowser/#/R-RNO-6803063 RNASEs bind bacterial LPS, PGN IEA Rattus norvegicus 55424 R-RNO-8862300 https://reactome.org/PathwayBrowser/#/R-RNO-8862300 LYZ binds bacterial peptidoglycan IEA Rattus norvegicus 55424 R-RNO-8862320 https://reactome.org/PathwayBrowser/#/R-RNO-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Rattus norvegicus 55424 R-SSC-6789072 https://reactome.org/PathwayBrowser/#/R-SSC-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Sus scrofa 55424 R-SSC-6799959 https://reactome.org/PathwayBrowser/#/R-SSC-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Sus scrofa 55424 R-SSC-6799977 https://reactome.org/PathwayBrowser/#/R-SSC-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Sus scrofa 55424 R-SSC-6799981 https://reactome.org/PathwayBrowser/#/R-SSC-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Sus scrofa 55424 R-SSC-6801808 https://reactome.org/PathwayBrowser/#/R-SSC-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Sus scrofa 55424 R-SSC-6803063 https://reactome.org/PathwayBrowser/#/R-SSC-6803063 RNASEs bind bacterial LPS, PGN IEA Sus scrofa 55424 R-SSC-8862300 https://reactome.org/PathwayBrowser/#/R-SSC-8862300 LYZ binds bacterial peptidoglycan IEA Sus scrofa 55424 R-SSC-8862320 https://reactome.org/PathwayBrowser/#/R-SSC-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Sus scrofa 55424 R-XTR-6789072 https://reactome.org/PathwayBrowser/#/R-XTR-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Xenopus tropicalis 55424 R-XTR-6799959 https://reactome.org/PathwayBrowser/#/R-XTR-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Xenopus tropicalis 55424 R-XTR-6799977 https://reactome.org/PathwayBrowser/#/R-XTR-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Xenopus tropicalis 55424 R-XTR-6799981 https://reactome.org/PathwayBrowser/#/R-XTR-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Xenopus tropicalis 55424 R-XTR-6801808 https://reactome.org/PathwayBrowser/#/R-XTR-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Xenopus tropicalis 55424 R-XTR-8862300 https://reactome.org/PathwayBrowser/#/R-XTR-8862300 LYZ binds bacterial peptidoglycan IEA Xenopus tropicalis 55424 R-XTR-8862320 https://reactome.org/PathwayBrowser/#/R-XTR-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Xenopus tropicalis 55458 R-BTA-8936519 https://reactome.org/PathwayBrowser/#/R-BTA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Bos taurus 55458 R-CFA-8936519 https://reactome.org/PathwayBrowser/#/R-CFA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Canis familiaris 55458 R-GGA-8936519 https://reactome.org/PathwayBrowser/#/R-GGA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Gallus gallus 55458 R-HSA-8936519 https://reactome.org/PathwayBrowser/#/R-HSA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones TAS Homo sapiens 55458 R-MMU-8936519 https://reactome.org/PathwayBrowser/#/R-MMU-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Mus musculus 55458 R-RNO-8936519 https://reactome.org/PathwayBrowser/#/R-RNO-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Rattus norvegicus 55458 R-SSC-8936519 https://reactome.org/PathwayBrowser/#/R-SSC-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Sus scrofa 55458 R-XTR-8936519 https://reactome.org/PathwayBrowser/#/R-XTR-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Xenopus tropicalis 5547 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 5547 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 5547 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 5547 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 5547 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 5547 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 5547 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 5547 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 5547 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 5547 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 5547 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 5547 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 5547 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 5547 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 5547 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 5547 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 5547 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 5547 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 5547 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 5547 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 5547 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 5547 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 5547 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 5547 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 5547 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 5547 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 5547 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 5547 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 5547 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 5547 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 5547 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 5547 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 5547 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 5547 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 5547 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 5547 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 5547 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 5547 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 5547 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 5547 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 5547 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 5547 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 55478 R-BTA-6803063 https://reactome.org/PathwayBrowser/#/R-BTA-6803063 RNASEs bind bacterial LPS, PGN IEA Bos taurus 55478 R-DRE-6803063 https://reactome.org/PathwayBrowser/#/R-DRE-6803063 RNASEs bind bacterial LPS, PGN IEA Danio rerio 55478 R-GGA-6803063 https://reactome.org/PathwayBrowser/#/R-GGA-6803063 RNASEs bind bacterial LPS, PGN IEA Gallus gallus 55478 R-HSA-6789185 https://reactome.org/PathwayBrowser/#/R-HSA-6789185 Chloride ion and N-acyl group react to chloramide TAS Homo sapiens 55478 R-HSA-6789208 https://reactome.org/PathwayBrowser/#/R-HSA-6789208 HOCl-induced glycosaminoglycan fragmentation TAS Homo sapiens 55478 R-HSA-6803063 https://reactome.org/PathwayBrowser/#/R-HSA-6803063 RNASEs bind bacterial LPS, PGN TAS Homo sapiens 55478 R-MMU-6803063 https://reactome.org/PathwayBrowser/#/R-MMU-6803063 RNASEs bind bacterial LPS, PGN IEA Mus musculus 55478 R-RNO-6803063 https://reactome.org/PathwayBrowser/#/R-RNO-6803063 RNASEs bind bacterial LPS, PGN IEA Rattus norvegicus 55478 R-SSC-6803063 https://reactome.org/PathwayBrowser/#/R-SSC-6803063 RNASEs bind bacterial LPS, PGN IEA Sus scrofa 55528 R-BTA-893596 https://reactome.org/PathwayBrowser/#/R-BTA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Bos taurus 55528 R-CEL-893596 https://reactome.org/PathwayBrowser/#/R-CEL-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Caenorhabditis elegans 55528 R-CFA-893596 https://reactome.org/PathwayBrowser/#/R-CFA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Canis familiaris 55528 R-DDI-893596 https://reactome.org/PathwayBrowser/#/R-DDI-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Dictyostelium discoideum 55528 R-DME-893596 https://reactome.org/PathwayBrowser/#/R-DME-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Drosophila melanogaster 55528 R-DRE-893596 https://reactome.org/PathwayBrowser/#/R-DRE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Danio rerio 55528 R-GGA-893596 https://reactome.org/PathwayBrowser/#/R-GGA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Gallus gallus 55528 R-HSA-893596 https://reactome.org/PathwayBrowser/#/R-HSA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu TAS Homo sapiens 55528 R-MMU-893596 https://reactome.org/PathwayBrowser/#/R-MMU-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Mus musculus 55528 R-RNO-893596 https://reactome.org/PathwayBrowser/#/R-RNO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Rattus norvegicus 55528 R-SCE-893596 https://reactome.org/PathwayBrowser/#/R-SCE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Saccharomyces cerevisiae 55528 R-SPO-893596 https://reactome.org/PathwayBrowser/#/R-SPO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Schizosaccharomyces pombe 55528 R-SSC-893596 https://reactome.org/PathwayBrowser/#/R-SSC-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Sus scrofa 55528 R-XTR-893596 https://reactome.org/PathwayBrowser/#/R-XTR-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Xenopus tropicalis 5553 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 5553 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 5553 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 5553 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 5553 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 5553 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 5553 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 5553 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 5553 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 5553 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 5553 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 5558 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 5558 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 5558 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 5558 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 5558 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 5558 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 5558 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 5558 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 5558 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 5558 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 5558 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 5615 R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 5615 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 5615 R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 5615 R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 5615 R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 5615 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 5615 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 5615 R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 5615 R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 5615 R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 5615 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 5615 R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 566274 R-BTA-2161613 https://reactome.org/PathwayBrowser/#/R-BTA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Bos taurus 566274 R-CFA-2161613 https://reactome.org/PathwayBrowser/#/R-CFA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Canis familiaris 566274 R-GGA-2161613 https://reactome.org/PathwayBrowser/#/R-GGA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Gallus gallus 566274 R-HSA-2161613 https://reactome.org/PathwayBrowser/#/R-HSA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 TAS Homo sapiens 566274 R-MMU-2161613 https://reactome.org/PathwayBrowser/#/R-MMU-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Mus musculus 566274 R-RNO-2161613 https://reactome.org/PathwayBrowser/#/R-RNO-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Rattus norvegicus 566274 R-SSC-2161613 https://reactome.org/PathwayBrowser/#/R-SSC-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Sus scrofa 5674 R-HSA-1218824 https://reactome.org/PathwayBrowser/#/R-HSA-1218824 HSP90 is inactivated by binding to benzaquinoid ansamycins TAS Homo sapiens 57259 R-BTA-8982667 https://reactome.org/PathwayBrowser/#/R-BTA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Bos taurus 57259 R-CEL-8982667 https://reactome.org/PathwayBrowser/#/R-CEL-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Caenorhabditis elegans 57259 R-CFA-8982667 https://reactome.org/PathwayBrowser/#/R-CFA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Canis familiaris 57259 R-DDI-8982667 https://reactome.org/PathwayBrowser/#/R-DDI-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Dictyostelium discoideum 57259 R-DME-8982667 https://reactome.org/PathwayBrowser/#/R-DME-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Drosophila melanogaster 57259 R-DRE-8982667 https://reactome.org/PathwayBrowser/#/R-DRE-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Danio rerio 57259 R-GGA-8982667 https://reactome.org/PathwayBrowser/#/R-GGA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Gallus gallus 57259 R-HSA-8982667 https://reactome.org/PathwayBrowser/#/R-HSA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P TAS Homo sapiens 57259 R-MMU-8982667 https://reactome.org/PathwayBrowser/#/R-MMU-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Mus musculus 57259 R-PFA-8982667 https://reactome.org/PathwayBrowser/#/R-PFA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Plasmodium falciparum 57259 R-RNO-8982667 https://reactome.org/PathwayBrowser/#/R-RNO-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Rattus norvegicus 57259 R-SCE-8982667 https://reactome.org/PathwayBrowser/#/R-SCE-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Saccharomyces cerevisiae 57259 R-SPO-8982667 https://reactome.org/PathwayBrowser/#/R-SPO-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Schizosaccharomyces pombe 57259 R-SSC-8982667 https://reactome.org/PathwayBrowser/#/R-SSC-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Sus scrofa 57259 R-XTR-8982667 https://reactome.org/PathwayBrowser/#/R-XTR-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Xenopus tropicalis 57265 R-BTA-162730 https://reactome.org/PathwayBrowser/#/R-BTA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Bos taurus 57265 R-BTA-162857 https://reactome.org/PathwayBrowser/#/R-BTA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Bos taurus 57265 R-CEL-162857 https://reactome.org/PathwayBrowser/#/R-CEL-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Caenorhabditis elegans 57265 R-CFA-162857 https://reactome.org/PathwayBrowser/#/R-CFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Canis familiaris 57265 R-DDI-162857 https://reactome.org/PathwayBrowser/#/R-DDI-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Dictyostelium discoideum 57265 R-DME-162857 https://reactome.org/PathwayBrowser/#/R-DME-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Drosophila melanogaster 57265 R-GGA-162730 https://reactome.org/PathwayBrowser/#/R-GGA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Gallus gallus 57265 R-GGA-162857 https://reactome.org/PathwayBrowser/#/R-GGA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Gallus gallus 57265 R-HSA-162730 https://reactome.org/PathwayBrowser/#/R-HSA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP TAS Homo sapiens 57265 R-HSA-162857 https://reactome.org/PathwayBrowser/#/R-HSA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate TAS Homo sapiens 57265 R-MMU-162730 https://reactome.org/PathwayBrowser/#/R-MMU-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Mus musculus 57265 R-MMU-162857 https://reactome.org/PathwayBrowser/#/R-MMU-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Mus musculus 57265 R-PFA-162857 https://reactome.org/PathwayBrowser/#/R-PFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Plasmodium falciparum 57265 R-RNO-162730 https://reactome.org/PathwayBrowser/#/R-RNO-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Rattus norvegicus 57265 R-RNO-162857 https://reactome.org/PathwayBrowser/#/R-RNO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Rattus norvegicus 57265 R-SCE-162857 https://reactome.org/PathwayBrowser/#/R-SCE-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Saccharomyces cerevisiae 57265 R-SPO-162857 https://reactome.org/PathwayBrowser/#/R-SPO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Schizosaccharomyces pombe 57265 R-SSC-162730 https://reactome.org/PathwayBrowser/#/R-SSC-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Sus scrofa 57265 R-SSC-162857 https://reactome.org/PathwayBrowser/#/R-SSC-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Sus scrofa 57265 R-XTR-162730 https://reactome.org/PathwayBrowser/#/R-XTR-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Xenopus tropicalis 57265 R-XTR-162857 https://reactome.org/PathwayBrowser/#/R-XTR-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Xenopus tropicalis 57273 R-BTA-1028788 https://reactome.org/PathwayBrowser/#/R-BTA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Bos taurus 57273 R-BTA-5693925 https://reactome.org/PathwayBrowser/#/R-BTA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Bos taurus 57273 R-BTA-742345 https://reactome.org/PathwayBrowser/#/R-BTA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Bos taurus 57273 R-BTA-9033949 https://reactome.org/PathwayBrowser/#/R-BTA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Bos taurus 57273 R-BTA-9036987 https://reactome.org/PathwayBrowser/#/R-BTA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Bos taurus 57273 R-BTA-9603982 https://reactome.org/PathwayBrowser/#/R-BTA-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Bos taurus 57273 R-BTA-9603983 https://reactome.org/PathwayBrowser/#/R-BTA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Bos taurus 57273 R-BTA-9603984 https://reactome.org/PathwayBrowser/#/R-BTA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Bos taurus 57273 R-BTA-9603986 https://reactome.org/PathwayBrowser/#/R-BTA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Bos taurus 57273 R-BTA-9605609 https://reactome.org/PathwayBrowser/#/R-BTA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Bos taurus 57273 R-BTA-9605644 https://reactome.org/PathwayBrowser/#/R-BTA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Bos taurus 57273 R-BTA-9605682 https://reactome.org/PathwayBrowser/#/R-BTA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Bos taurus 57273 R-BTA-9846332 https://reactome.org/PathwayBrowser/#/R-BTA-9846332 FUT1,2 transfer fucose to gangliosides IEA Bos taurus 57273 R-CEL-1028788 https://reactome.org/PathwayBrowser/#/R-CEL-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Caenorhabditis elegans 57273 R-CEL-5693925 https://reactome.org/PathwayBrowser/#/R-CEL-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Caenorhabditis elegans 57273 R-CEL-742345 https://reactome.org/PathwayBrowser/#/R-CEL-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Caenorhabditis elegans 57273 R-CEL-9033949 https://reactome.org/PathwayBrowser/#/R-CEL-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Caenorhabditis elegans 57273 R-CEL-9036987 https://reactome.org/PathwayBrowser/#/R-CEL-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Caenorhabditis elegans 57273 R-CEL-9603982 https://reactome.org/PathwayBrowser/#/R-CEL-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Caenorhabditis elegans 57273 R-CEL-9603983 https://reactome.org/PathwayBrowser/#/R-CEL-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Caenorhabditis elegans 57273 R-CEL-9603984 https://reactome.org/PathwayBrowser/#/R-CEL-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Caenorhabditis elegans 57273 R-CEL-9603986 https://reactome.org/PathwayBrowser/#/R-CEL-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Caenorhabditis elegans 57273 R-CEL-9605609 https://reactome.org/PathwayBrowser/#/R-CEL-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Caenorhabditis elegans 57273 R-CEL-9605644 https://reactome.org/PathwayBrowser/#/R-CEL-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Caenorhabditis elegans 57273 R-CEL-9605682 https://reactome.org/PathwayBrowser/#/R-CEL-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Caenorhabditis elegans 57273 R-CEL-9846332 https://reactome.org/PathwayBrowser/#/R-CEL-9846332 FUT1,2 transfer fucose to gangliosides IEA Caenorhabditis elegans 57273 R-CFA-1028788 https://reactome.org/PathwayBrowser/#/R-CFA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Canis familiaris 57273 R-CFA-5693925 https://reactome.org/PathwayBrowser/#/R-CFA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Canis familiaris 57273 R-CFA-742345 https://reactome.org/PathwayBrowser/#/R-CFA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Canis familiaris 57273 R-CFA-9036987 https://reactome.org/PathwayBrowser/#/R-CFA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Canis familiaris 57273 R-CFA-9603982 https://reactome.org/PathwayBrowser/#/R-CFA-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Canis familiaris 57273 R-CFA-9603983 https://reactome.org/PathwayBrowser/#/R-CFA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Canis familiaris 57273 R-CFA-9603984 https://reactome.org/PathwayBrowser/#/R-CFA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Canis familiaris 57273 R-CFA-9603986 https://reactome.org/PathwayBrowser/#/R-CFA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Canis familiaris 57273 R-CFA-9605609 https://reactome.org/PathwayBrowser/#/R-CFA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Canis familiaris 57273 R-CFA-9605644 https://reactome.org/PathwayBrowser/#/R-CFA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Canis familiaris 57273 R-CFA-9605682 https://reactome.org/PathwayBrowser/#/R-CFA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Canis familiaris 57273 R-CFA-9846332 https://reactome.org/PathwayBrowser/#/R-CFA-9846332 FUT1,2 transfer fucose to gangliosides IEA Canis familiaris 57273 R-DDI-5693925 https://reactome.org/PathwayBrowser/#/R-DDI-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Dictyostelium discoideum 57273 R-DDI-742345 https://reactome.org/PathwayBrowser/#/R-DDI-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Dictyostelium discoideum 57273 R-DDI-9603984 https://reactome.org/PathwayBrowser/#/R-DDI-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Dictyostelium discoideum 57273 R-DDI-9603986 https://reactome.org/PathwayBrowser/#/R-DDI-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Dictyostelium discoideum 57273 R-DDI-9605609 https://reactome.org/PathwayBrowser/#/R-DDI-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Dictyostelium discoideum 57273 R-DDI-9605644 https://reactome.org/PathwayBrowser/#/R-DDI-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Dictyostelium discoideum 57273 R-DDI-9605682 https://reactome.org/PathwayBrowser/#/R-DDI-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Dictyostelium discoideum 57273 R-DME-1028788 https://reactome.org/PathwayBrowser/#/R-DME-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Drosophila melanogaster 57273 R-DME-5693925 https://reactome.org/PathwayBrowser/#/R-DME-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Drosophila melanogaster 57273 R-DME-742345 https://reactome.org/PathwayBrowser/#/R-DME-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Drosophila melanogaster 57273 R-DME-9603984 https://reactome.org/PathwayBrowser/#/R-DME-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Drosophila melanogaster 57273 R-DME-9603986 https://reactome.org/PathwayBrowser/#/R-DME-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Drosophila melanogaster 57273 R-DME-9605609 https://reactome.org/PathwayBrowser/#/R-DME-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Drosophila melanogaster 57273 R-DME-9605644 https://reactome.org/PathwayBrowser/#/R-DME-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Drosophila melanogaster 57273 R-DME-9605682 https://reactome.org/PathwayBrowser/#/R-DME-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Drosophila melanogaster 57273 R-DRE-1028788 https://reactome.org/PathwayBrowser/#/R-DRE-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Danio rerio 57273 R-DRE-9603984 https://reactome.org/PathwayBrowser/#/R-DRE-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Danio rerio 57273 R-DRE-9605682 https://reactome.org/PathwayBrowser/#/R-DRE-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Danio rerio 57273 R-GGA-1028788 https://reactome.org/PathwayBrowser/#/R-GGA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Gallus gallus 57273 R-GGA-742345 https://reactome.org/PathwayBrowser/#/R-GGA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Gallus gallus 57273 R-GGA-9603984 https://reactome.org/PathwayBrowser/#/R-GGA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Gallus gallus 57273 R-GGA-9605682 https://reactome.org/PathwayBrowser/#/R-GGA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Gallus gallus 57273 R-HSA-1028788 https://reactome.org/PathwayBrowser/#/R-HSA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP TAS Homo sapiens 57273 R-HSA-5693925 https://reactome.org/PathwayBrowser/#/R-HSA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc TAS Homo sapiens 57273 R-HSA-742345 https://reactome.org/PathwayBrowser/#/R-HSA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen TAS Homo sapiens 57273 R-HSA-9033949 https://reactome.org/PathwayBrowser/#/R-HSA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC TAS Homo sapiens 57273 R-HSA-9036987 https://reactome.org/PathwayBrowser/#/R-HSA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec TAS Homo sapiens 57273 R-HSA-9603982 https://reactome.org/PathwayBrowser/#/R-HSA-9603982 FUT2 transfers Fuc to LeA to form LeB TAS Homo sapiens 57273 R-HSA-9603983 https://reactome.org/PathwayBrowser/#/R-HSA-9603983 FUT2 transfers Fuc to LeX to form LeY TAS Homo sapiens 57273 R-HSA-9603984 https://reactome.org/PathwayBrowser/#/R-HSA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX TAS Homo sapiens 57273 R-HSA-9603986 https://reactome.org/PathwayBrowser/#/R-HSA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA TAS Homo sapiens 57273 R-HSA-9605609 https://reactome.org/PathwayBrowser/#/R-HSA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA TAS Homo sapiens 57273 R-HSA-9605644 https://reactome.org/PathwayBrowser/#/R-HSA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA TAS Homo sapiens 57273 R-HSA-9605682 https://reactome.org/PathwayBrowser/#/R-HSA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX TAS Homo sapiens 57273 R-HSA-9846332 https://reactome.org/PathwayBrowser/#/R-HSA-9846332 FUT1,2 transfer fucose to gangliosides TAS Homo sapiens 57273 R-MMU-1028788 https://reactome.org/PathwayBrowser/#/R-MMU-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Mus musculus 57273 R-MMU-742345 https://reactome.org/PathwayBrowser/#/R-MMU-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Mus musculus 57273 R-MMU-9033949 https://reactome.org/PathwayBrowser/#/R-MMU-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Mus musculus 57273 R-MMU-9036987 https://reactome.org/PathwayBrowser/#/R-MMU-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Mus musculus 57273 R-MMU-9603982 https://reactome.org/PathwayBrowser/#/R-MMU-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Mus musculus 57273 R-MMU-9603983 https://reactome.org/PathwayBrowser/#/R-MMU-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Mus musculus 57273 R-MMU-9603984 https://reactome.org/PathwayBrowser/#/R-MMU-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Mus musculus 57273 R-MMU-9605682 https://reactome.org/PathwayBrowser/#/R-MMU-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Mus musculus 57273 R-MMU-9846332 https://reactome.org/PathwayBrowser/#/R-MMU-9846332 FUT1,2 transfer fucose to gangliosides IEA Mus musculus 57273 R-PFA-742345 https://reactome.org/PathwayBrowser/#/R-PFA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Plasmodium falciparum 57273 R-RNO-1028788 https://reactome.org/PathwayBrowser/#/R-RNO-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Rattus norvegicus 57273 R-RNO-742345 https://reactome.org/PathwayBrowser/#/R-RNO-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Rattus norvegicus 57273 R-RNO-9033949 https://reactome.org/PathwayBrowser/#/R-RNO-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Rattus norvegicus 57273 R-RNO-9036987 https://reactome.org/PathwayBrowser/#/R-RNO-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Rattus norvegicus 57273 R-RNO-9603982 https://reactome.org/PathwayBrowser/#/R-RNO-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Rattus norvegicus 57273 R-RNO-9603983 https://reactome.org/PathwayBrowser/#/R-RNO-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Rattus norvegicus 57273 R-RNO-9603984 https://reactome.org/PathwayBrowser/#/R-RNO-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Rattus norvegicus 57273 R-RNO-9605682 https://reactome.org/PathwayBrowser/#/R-RNO-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Rattus norvegicus 57273 R-RNO-9846332 https://reactome.org/PathwayBrowser/#/R-RNO-9846332 FUT1,2 transfer fucose to gangliosides IEA Rattus norvegicus 57273 R-SPO-742345 https://reactome.org/PathwayBrowser/#/R-SPO-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Schizosaccharomyces pombe 57273 R-SSC-1028788 https://reactome.org/PathwayBrowser/#/R-SSC-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Sus scrofa 57273 R-SSC-5693925 https://reactome.org/PathwayBrowser/#/R-SSC-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Sus scrofa 57273 R-SSC-742345 https://reactome.org/PathwayBrowser/#/R-SSC-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Sus scrofa 57273 R-SSC-9033949 https://reactome.org/PathwayBrowser/#/R-SSC-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Sus scrofa 57273 R-SSC-9036987 https://reactome.org/PathwayBrowser/#/R-SSC-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Sus scrofa 57273 R-SSC-9603982 https://reactome.org/PathwayBrowser/#/R-SSC-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Sus scrofa 57273 R-SSC-9603983 https://reactome.org/PathwayBrowser/#/R-SSC-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Sus scrofa 57273 R-SSC-9603984 https://reactome.org/PathwayBrowser/#/R-SSC-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Sus scrofa 57273 R-SSC-9603986 https://reactome.org/PathwayBrowser/#/R-SSC-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Sus scrofa 57273 R-SSC-9605609 https://reactome.org/PathwayBrowser/#/R-SSC-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Sus scrofa 57273 R-SSC-9605644 https://reactome.org/PathwayBrowser/#/R-SSC-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Sus scrofa 57273 R-SSC-9605682 https://reactome.org/PathwayBrowser/#/R-SSC-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Sus scrofa 57273 R-SSC-9846332 https://reactome.org/PathwayBrowser/#/R-SSC-9846332 FUT1,2 transfer fucose to gangliosides IEA Sus scrofa 57273 R-XTR-1028788 https://reactome.org/PathwayBrowser/#/R-XTR-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Xenopus tropicalis 57273 R-XTR-5693925 https://reactome.org/PathwayBrowser/#/R-XTR-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Xenopus tropicalis 57273 R-XTR-742345 https://reactome.org/PathwayBrowser/#/R-XTR-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Xenopus tropicalis 57273 R-XTR-9033949 https://reactome.org/PathwayBrowser/#/R-XTR-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Xenopus tropicalis 57273 R-XTR-9036987 https://reactome.org/PathwayBrowser/#/R-XTR-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Xenopus tropicalis 57273 R-XTR-9603982 https://reactome.org/PathwayBrowser/#/R-XTR-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Xenopus tropicalis 57273 R-XTR-9603983 https://reactome.org/PathwayBrowser/#/R-XTR-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Xenopus tropicalis 57273 R-XTR-9603984 https://reactome.org/PathwayBrowser/#/R-XTR-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Xenopus tropicalis 57273 R-XTR-9603986 https://reactome.org/PathwayBrowser/#/R-XTR-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Xenopus tropicalis 57273 R-XTR-9605609 https://reactome.org/PathwayBrowser/#/R-XTR-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Xenopus tropicalis 57273 R-XTR-9605644 https://reactome.org/PathwayBrowser/#/R-XTR-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Xenopus tropicalis 57273 R-XTR-9605682 https://reactome.org/PathwayBrowser/#/R-XTR-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Xenopus tropicalis 57273 R-XTR-9846332 https://reactome.org/PathwayBrowser/#/R-XTR-9846332 FUT1,2 transfer fucose to gangliosides IEA Xenopus tropicalis 57286 R-BTA-191323 https://reactome.org/PathwayBrowser/#/R-BTA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Bos taurus 57286 R-BTA-5694494 https://reactome.org/PathwayBrowser/#/R-BTA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Bos taurus 57286 R-BTA-73916 https://reactome.org/PathwayBrowser/#/R-BTA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Bos taurus 57286 R-BTA-73918 https://reactome.org/PathwayBrowser/#/R-BTA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Bos taurus 57286 R-BTA-74177 https://reactome.org/PathwayBrowser/#/R-BTA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Bos taurus 57286 R-BTA-74181 https://reactome.org/PathwayBrowser/#/R-BTA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Bos taurus 57286 R-BTA-77312 https://reactome.org/PathwayBrowser/#/R-BTA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Bos taurus 57286 R-BTA-8848215 https://reactome.org/PathwayBrowser/#/R-BTA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Bos taurus 57286 R-CEL-191323 https://reactome.org/PathwayBrowser/#/R-CEL-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Caenorhabditis elegans 57286 R-CEL-5694494 https://reactome.org/PathwayBrowser/#/R-CEL-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Caenorhabditis elegans 57286 R-CEL-73916 https://reactome.org/PathwayBrowser/#/R-CEL-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Caenorhabditis elegans 57286 R-CEL-73918 https://reactome.org/PathwayBrowser/#/R-CEL-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Caenorhabditis elegans 57286 R-CEL-74177 https://reactome.org/PathwayBrowser/#/R-CEL-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Caenorhabditis elegans 57286 R-CEL-74181 https://reactome.org/PathwayBrowser/#/R-CEL-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Caenorhabditis elegans 57286 R-CEL-77312 https://reactome.org/PathwayBrowser/#/R-CEL-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Caenorhabditis elegans 57286 R-CFA-191323 https://reactome.org/PathwayBrowser/#/R-CFA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Canis familiaris 57286 R-CFA-73916 https://reactome.org/PathwayBrowser/#/R-CFA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Canis familiaris 57286 R-CFA-73918 https://reactome.org/PathwayBrowser/#/R-CFA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Canis familiaris 57286 R-CFA-74177 https://reactome.org/PathwayBrowser/#/R-CFA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Canis familiaris 57286 R-CFA-74181 https://reactome.org/PathwayBrowser/#/R-CFA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Canis familiaris 57286 R-CFA-77312 https://reactome.org/PathwayBrowser/#/R-CFA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Canis familiaris 57286 R-CFA-8848215 https://reactome.org/PathwayBrowser/#/R-CFA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Canis familiaris 57286 R-DDI-191323 https://reactome.org/PathwayBrowser/#/R-DDI-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Dictyostelium discoideum 57286 R-DDI-73916 https://reactome.org/PathwayBrowser/#/R-DDI-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Dictyostelium discoideum 57286 R-DDI-73918 https://reactome.org/PathwayBrowser/#/R-DDI-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Dictyostelium discoideum 57286 R-DDI-74177 https://reactome.org/PathwayBrowser/#/R-DDI-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Dictyostelium discoideum 57286 R-DDI-74181 https://reactome.org/PathwayBrowser/#/R-DDI-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Dictyostelium discoideum 57286 R-DDI-8848215 https://reactome.org/PathwayBrowser/#/R-DDI-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Dictyostelium discoideum 57286 R-DME-191323 https://reactome.org/PathwayBrowser/#/R-DME-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Drosophila melanogaster 57286 R-DME-73916 https://reactome.org/PathwayBrowser/#/R-DME-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Drosophila melanogaster 57286 R-DME-73918 https://reactome.org/PathwayBrowser/#/R-DME-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Drosophila melanogaster 57286 R-DME-74177 https://reactome.org/PathwayBrowser/#/R-DME-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Drosophila melanogaster 57286 R-DME-74181 https://reactome.org/PathwayBrowser/#/R-DME-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Drosophila melanogaster 57286 R-DME-8848215 https://reactome.org/PathwayBrowser/#/R-DME-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Drosophila melanogaster 57286 R-DRE-5694494 https://reactome.org/PathwayBrowser/#/R-DRE-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Danio rerio 57286 R-DRE-73916 https://reactome.org/PathwayBrowser/#/R-DRE-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Danio rerio 57286 R-DRE-74177 https://reactome.org/PathwayBrowser/#/R-DRE-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Danio rerio 57286 R-DRE-74181 https://reactome.org/PathwayBrowser/#/R-DRE-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Danio rerio 57286 R-DRE-77312 https://reactome.org/PathwayBrowser/#/R-DRE-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Danio rerio 57286 R-DRE-8848215 https://reactome.org/PathwayBrowser/#/R-DRE-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Danio rerio 57286 R-GGA-191323 https://reactome.org/PathwayBrowser/#/R-GGA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Gallus gallus 57286 R-GGA-5694494 https://reactome.org/PathwayBrowser/#/R-GGA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Gallus gallus 57286 R-GGA-73916 https://reactome.org/PathwayBrowser/#/R-GGA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Gallus gallus 57286 R-GGA-73918 https://reactome.org/PathwayBrowser/#/R-GGA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Gallus gallus 57286 R-GGA-74177 https://reactome.org/PathwayBrowser/#/R-GGA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Gallus gallus 57286 R-GGA-74181 https://reactome.org/PathwayBrowser/#/R-GGA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Gallus gallus 57286 R-GGA-77312 https://reactome.org/PathwayBrowser/#/R-GGA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Gallus gallus 57286 R-GGA-8848215 https://reactome.org/PathwayBrowser/#/R-GGA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Gallus gallus 57286 R-HSA-191323 https://reactome.org/PathwayBrowser/#/R-HSA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA TAS Homo sapiens 57286 R-HSA-5694494 https://reactome.org/PathwayBrowser/#/R-HSA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA TAS Homo sapiens 57286 R-HSA-73916 https://reactome.org/PathwayBrowser/#/R-HSA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA TAS Homo sapiens 57286 R-HSA-73918 https://reactome.org/PathwayBrowser/#/R-HSA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH TAS Homo sapiens 57286 R-HSA-74177 https://reactome.org/PathwayBrowser/#/R-HSA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA TAS Homo sapiens 57286 R-HSA-74181 https://reactome.org/PathwayBrowser/#/R-HSA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA TAS Homo sapiens 57286 R-HSA-77312 https://reactome.org/PathwayBrowser/#/R-HSA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H TAS Homo sapiens 57286 R-HSA-8848215 https://reactome.org/PathwayBrowser/#/R-HSA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA TAS Homo sapiens 57286 R-MMU-191323 https://reactome.org/PathwayBrowser/#/R-MMU-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Mus musculus 57286 R-MMU-5694494 https://reactome.org/PathwayBrowser/#/R-MMU-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Mus musculus 57286 R-MMU-73916 https://reactome.org/PathwayBrowser/#/R-MMU-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Mus musculus 57286 R-MMU-73918 https://reactome.org/PathwayBrowser/#/R-MMU-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Mus musculus 57286 R-MMU-74177 https://reactome.org/PathwayBrowser/#/R-MMU-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Mus musculus 57286 R-MMU-74181 https://reactome.org/PathwayBrowser/#/R-MMU-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Mus musculus 57286 R-MMU-77312 https://reactome.org/PathwayBrowser/#/R-MMU-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Mus musculus 57286 R-MMU-8848215 https://reactome.org/PathwayBrowser/#/R-MMU-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Mus musculus 57286 R-PFA-73916 https://reactome.org/PathwayBrowser/#/R-PFA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Plasmodium falciparum 57286 R-PFA-74181 https://reactome.org/PathwayBrowser/#/R-PFA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Plasmodium falciparum 57286 R-PFA-8848215 https://reactome.org/PathwayBrowser/#/R-PFA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Plasmodium falciparum 57286 R-RNO-191323 https://reactome.org/PathwayBrowser/#/R-RNO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Rattus norvegicus 57286 R-RNO-5694494 https://reactome.org/PathwayBrowser/#/R-RNO-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Rattus norvegicus 57286 R-RNO-73916 https://reactome.org/PathwayBrowser/#/R-RNO-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Rattus norvegicus 57286 R-RNO-73918 https://reactome.org/PathwayBrowser/#/R-RNO-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Rattus norvegicus 57286 R-RNO-74177 https://reactome.org/PathwayBrowser/#/R-RNO-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Rattus norvegicus 57286 R-RNO-74181 https://reactome.org/PathwayBrowser/#/R-RNO-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Rattus norvegicus 57286 R-RNO-77312 https://reactome.org/PathwayBrowser/#/R-RNO-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Rattus norvegicus 57286 R-RNO-8848215 https://reactome.org/PathwayBrowser/#/R-RNO-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Rattus norvegicus 57286 R-SCE-191323 https://reactome.org/PathwayBrowser/#/R-SCE-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Saccharomyces cerevisiae 57286 R-SCE-73918 https://reactome.org/PathwayBrowser/#/R-SCE-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Saccharomyces cerevisiae 57286 R-SCE-8848215 https://reactome.org/PathwayBrowser/#/R-SCE-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Saccharomyces cerevisiae 57286 R-SPO-191323 https://reactome.org/PathwayBrowser/#/R-SPO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Schizosaccharomyces pombe 57286 R-SPO-73918 https://reactome.org/PathwayBrowser/#/R-SPO-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Schizosaccharomyces pombe 57286 R-SPO-8848215 https://reactome.org/PathwayBrowser/#/R-SPO-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Schizosaccharomyces pombe 57286 R-SSC-191323 https://reactome.org/PathwayBrowser/#/R-SSC-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Sus scrofa 57286 R-SSC-5694494 https://reactome.org/PathwayBrowser/#/R-SSC-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Sus scrofa 57286 R-SSC-73916 https://reactome.org/PathwayBrowser/#/R-SSC-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Sus scrofa 57286 R-SSC-73918 https://reactome.org/PathwayBrowser/#/R-SSC-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Sus scrofa 57286 R-SSC-74177 https://reactome.org/PathwayBrowser/#/R-SSC-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Sus scrofa 57286 R-SSC-74181 https://reactome.org/PathwayBrowser/#/R-SSC-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Sus scrofa 57286 R-SSC-77312 https://reactome.org/PathwayBrowser/#/R-SSC-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Sus scrofa 57286 R-SSC-8848215 https://reactome.org/PathwayBrowser/#/R-SSC-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Sus scrofa 57286 R-XTR-5694494 https://reactome.org/PathwayBrowser/#/R-XTR-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Xenopus tropicalis 57286 R-XTR-73916 https://reactome.org/PathwayBrowser/#/R-XTR-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Xenopus tropicalis 57286 R-XTR-74177 https://reactome.org/PathwayBrowser/#/R-XTR-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Xenopus tropicalis 57286 R-XTR-74181 https://reactome.org/PathwayBrowser/#/R-XTR-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Xenopus tropicalis 57286 R-XTR-77312 https://reactome.org/PathwayBrowser/#/R-XTR-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Xenopus tropicalis 57286 R-XTR-8848215 https://reactome.org/PathwayBrowser/#/R-XTR-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Xenopus tropicalis 57287 R-BTA-1482533 https://reactome.org/PathwayBrowser/#/R-BTA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Bos taurus 57287 R-BTA-1482539 https://reactome.org/PathwayBrowser/#/R-BTA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Bos taurus 57287 R-BTA-1482546 https://reactome.org/PathwayBrowser/#/R-BTA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Bos taurus 57287 R-BTA-1482547 https://reactome.org/PathwayBrowser/#/R-BTA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Bos taurus 57287 R-BTA-1482548 https://reactome.org/PathwayBrowser/#/R-BTA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Bos taurus 57287 R-BTA-1482598 https://reactome.org/PathwayBrowser/#/R-BTA-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Bos taurus 57287 R-BTA-1482626 https://reactome.org/PathwayBrowser/#/R-BTA-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Bos taurus 57287 R-BTA-1482635 https://reactome.org/PathwayBrowser/#/R-BTA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Bos taurus 57287 R-BTA-1482636 https://reactome.org/PathwayBrowser/#/R-BTA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Bos taurus 57287 R-BTA-1482646 https://reactome.org/PathwayBrowser/#/R-BTA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Bos taurus 57287 R-BTA-1482667 https://reactome.org/PathwayBrowser/#/R-BTA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Bos taurus 57287 R-BTA-1482689 https://reactome.org/PathwayBrowser/#/R-BTA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Bos taurus 57287 R-BTA-1482691 https://reactome.org/PathwayBrowser/#/R-BTA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Bos taurus 57287 R-BTA-1482695 https://reactome.org/PathwayBrowser/#/R-BTA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Bos taurus 57287 R-BTA-1482775 https://reactome.org/PathwayBrowser/#/R-BTA-1482775 MLCL is acylated to CL by HADH (IM) IEA Bos taurus 57287 R-BTA-1482861 https://reactome.org/PathwayBrowser/#/R-BTA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Bos taurus 57287 R-BTA-1482867 https://reactome.org/PathwayBrowser/#/R-BTA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Bos taurus 57287 R-BTA-1482889 https://reactome.org/PathwayBrowser/#/R-BTA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Bos taurus 57287 R-BTA-1483002 https://reactome.org/PathwayBrowser/#/R-BTA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Bos taurus 57287 R-BTA-158832 https://reactome.org/PathwayBrowser/#/R-BTA-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Bos taurus 57287 R-BTA-159425 https://reactome.org/PathwayBrowser/#/R-BTA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 57287 R-BTA-159443 https://reactome.org/PathwayBrowser/#/R-BTA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Bos taurus 57287 R-BTA-159566 https://reactome.org/PathwayBrowser/#/R-BTA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Bos taurus 57287 R-BTA-159567 https://reactome.org/PathwayBrowser/#/R-BTA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Bos taurus 57287 R-BTA-159574 https://reactome.org/PathwayBrowser/#/R-BTA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Bos taurus 57287 R-BTA-162683 https://reactome.org/PathwayBrowser/#/R-BTA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Bos taurus 57287 R-BTA-1678660 https://reactome.org/PathwayBrowser/#/R-BTA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Bos taurus 57287 R-BTA-174959 https://reactome.org/PathwayBrowser/#/R-BTA-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Bos taurus 57287 R-BTA-177157 https://reactome.org/PathwayBrowser/#/R-BTA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Bos taurus 57287 R-BTA-189442 https://reactome.org/PathwayBrowser/#/R-BTA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Bos taurus 57287 R-BTA-191323 https://reactome.org/PathwayBrowser/#/R-BTA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Bos taurus 57287 R-BTA-191352 https://reactome.org/PathwayBrowser/#/R-BTA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Bos taurus 57287 R-BTA-192137 https://reactome.org/PathwayBrowser/#/R-BTA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 57287 R-BTA-192341 https://reactome.org/PathwayBrowser/#/R-BTA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Bos taurus 57287 R-BTA-193385 https://reactome.org/PathwayBrowser/#/R-BTA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Bos taurus 57287 R-BTA-193401 https://reactome.org/PathwayBrowser/#/R-BTA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 57287 R-BTA-193407 https://reactome.org/PathwayBrowser/#/R-BTA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 57287 R-BTA-193424 https://reactome.org/PathwayBrowser/#/R-BTA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 57287 R-BTA-193533 https://reactome.org/PathwayBrowser/#/R-BTA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Bos taurus 57287 R-BTA-193711 https://reactome.org/PathwayBrowser/#/R-BTA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 57287 R-BTA-193727 https://reactome.org/PathwayBrowser/#/R-BTA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 57287 R-BTA-193743 https://reactome.org/PathwayBrowser/#/R-BTA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 57287 R-BTA-193766 https://reactome.org/PathwayBrowser/#/R-BTA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 57287 R-BTA-196773 https://reactome.org/PathwayBrowser/#/R-BTA-196773 COASY phosphorylates DP-CoA IEA Bos taurus 57287 R-BTA-196857 https://reactome.org/PathwayBrowser/#/R-BTA-196857 PANK2 phosphorylates PanK IEA Bos taurus 57287 R-BTA-199202 https://reactome.org/PathwayBrowser/#/R-BTA-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Bos taurus 57287 R-BTA-199216 https://reactome.org/PathwayBrowser/#/R-BTA-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Bos taurus 57287 R-BTA-200406 https://reactome.org/PathwayBrowser/#/R-BTA-200406 CPT1A,B transfers PALM to CAR IEA Bos taurus 57287 R-BTA-200410 https://reactome.org/PathwayBrowser/#/R-BTA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Bos taurus 57287 R-BTA-201035 https://reactome.org/PathwayBrowser/#/R-BTA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Bos taurus 57287 R-BTA-2046083 https://reactome.org/PathwayBrowser/#/R-BTA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Bos taurus 57287 R-BTA-2046085 https://reactome.org/PathwayBrowser/#/R-BTA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Bos taurus 57287 R-BTA-2046088 https://reactome.org/PathwayBrowser/#/R-BTA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Bos taurus 57287 R-BTA-2046090 https://reactome.org/PathwayBrowser/#/R-BTA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 57287 R-BTA-2046094 https://reactome.org/PathwayBrowser/#/R-BTA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Bos taurus 57287 R-BTA-2046095 https://reactome.org/PathwayBrowser/#/R-BTA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Bos taurus 57287 R-BTA-2046098 https://reactome.org/PathwayBrowser/#/R-BTA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Bos taurus 57287 R-BTA-2046100 https://reactome.org/PathwayBrowser/#/R-BTA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Bos taurus 57287 R-BTA-2066779 https://reactome.org/PathwayBrowser/#/R-BTA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Bos taurus 57287 R-BTA-2066781 https://reactome.org/PathwayBrowser/#/R-BTA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Bos taurus 57287 R-BTA-2066788 https://reactome.org/PathwayBrowser/#/R-BTA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Bos taurus 57287 R-BTA-2090085 https://reactome.org/PathwayBrowser/#/R-BTA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Bos taurus 57287 R-BTA-209792 https://reactome.org/PathwayBrowser/#/R-BTA-209792 N-acetylation of serotonin IEA Bos taurus 57287 R-BTA-2465919 https://reactome.org/PathwayBrowser/#/R-BTA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Bos taurus 57287 R-BTA-2468039 https://reactome.org/PathwayBrowser/#/R-BTA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Bos taurus 57287 R-BTA-2473152 https://reactome.org/PathwayBrowser/#/R-BTA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Bos taurus 57287 R-BTA-2534076 https://reactome.org/PathwayBrowser/#/R-BTA-2534076 Unknown Nat N-acylates Gly in Gnat1 TAS Bos taurus 57287 R-BTA-2534087 https://reactome.org/PathwayBrowser/#/R-BTA-2534087 NMT1/2 transfer MYS to GNAT1 IEA Bos taurus 57287 R-BTA-2545203 https://reactome.org/PathwayBrowser/#/R-BTA-2545203 Deacetylation of cleaved cohesin IEA Bos taurus 57287 R-BTA-2545253 https://reactome.org/PathwayBrowser/#/R-BTA-2545253 Deacetylation of cohesin IEA Bos taurus 57287 R-BTA-264622 https://reactome.org/PathwayBrowser/#/R-BTA-264622 Cho is acetylated to AcCho by CHAT IEA Bos taurus 57287 R-BTA-3318413 https://reactome.org/PathwayBrowser/#/R-BTA-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Bos taurus 57287 R-BTA-3318486 https://reactome.org/PathwayBrowser/#/R-BTA-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Bos taurus 57287 R-BTA-3321805 https://reactome.org/PathwayBrowser/#/R-BTA-3321805 NSL acetylates histone H4 IEA Bos taurus 57287 R-BTA-3321883 https://reactome.org/PathwayBrowser/#/R-BTA-3321883 MSL acetylates histone H4 IEA Bos taurus 57287 R-BTA-3371554 https://reactome.org/PathwayBrowser/#/R-BTA-3371554 HSF1 acetylation at Lys80 IEA Bos taurus 57287 R-BTA-351207 https://reactome.org/PathwayBrowser/#/R-BTA-351207 Spermine => N-acetylated spermine IEA Bos taurus 57287 R-BTA-351208 https://reactome.org/PathwayBrowser/#/R-BTA-351208 Spermidine => N-acetylated spermidine IEA Bos taurus 57287 R-BTA-3662318 https://reactome.org/PathwayBrowser/#/R-BTA-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Bos taurus 57287 R-BTA-3662335 https://reactome.org/PathwayBrowser/#/R-BTA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Bos taurus 57287 R-BTA-389622 https://reactome.org/PathwayBrowser/#/R-BTA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 57287 R-BTA-389632 https://reactome.org/PathwayBrowser/#/R-BTA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 57287 R-BTA-390224 https://reactome.org/PathwayBrowser/#/R-BTA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Bos taurus 57287 R-BTA-390250 https://reactome.org/PathwayBrowser/#/R-BTA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Bos taurus 57287 R-BTA-390281 https://reactome.org/PathwayBrowser/#/R-BTA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Bos taurus 57287 R-BTA-390284 https://reactome.org/PathwayBrowser/#/R-BTA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Bos taurus 57287 R-BTA-390291 https://reactome.org/PathwayBrowser/#/R-BTA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Bos taurus 57287 R-BTA-390304 https://reactome.org/PathwayBrowser/#/R-BTA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Bos taurus 57287 R-BTA-390425 https://reactome.org/PathwayBrowser/#/R-BTA-390425 FAR1 reduces PalmCoA to HXOL IEA Bos taurus 57287 R-BTA-390438 https://reactome.org/PathwayBrowser/#/R-BTA-390438 FAR2 reduces PalmCoA to HXOL IEA Bos taurus 57287 R-BTA-428127 https://reactome.org/PathwayBrowser/#/R-BTA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Bos taurus 57287 R-BTA-428185 https://reactome.org/PathwayBrowser/#/R-BTA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Bos taurus 57287 R-BTA-434382 https://reactome.org/PathwayBrowser/#/R-BTA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Bos taurus 57287 R-BTA-449734 https://reactome.org/PathwayBrowser/#/R-BTA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Bos taurus 57287 R-BTA-449911 https://reactome.org/PathwayBrowser/#/R-BTA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Bos taurus 57287 R-BTA-5250938 https://reactome.org/PathwayBrowser/#/R-BTA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Bos taurus 57287 R-BTA-5358343 https://reactome.org/PathwayBrowser/#/R-BTA-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Bos taurus 57287 R-BTA-548800 https://reactome.org/PathwayBrowser/#/R-BTA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Bos taurus 57287 R-BTA-548814 https://reactome.org/PathwayBrowser/#/R-BTA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Bos taurus 57287 R-BTA-548815 https://reactome.org/PathwayBrowser/#/R-BTA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Bos taurus 57287 R-BTA-548843 https://reactome.org/PathwayBrowser/#/R-BTA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Bos taurus 57287 R-BTA-549112 https://reactome.org/PathwayBrowser/#/R-BTA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Bos taurus 57287 R-BTA-5618328 https://reactome.org/PathwayBrowser/#/R-BTA-5618328 ATAT acetylates microtubules IEA Bos taurus 57287 R-BTA-5618331 https://reactome.org/PathwayBrowser/#/R-BTA-5618331 HDAC6 deacetylates microtubules IEA Bos taurus 57287 R-BTA-5628871 https://reactome.org/PathwayBrowser/#/R-BTA-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Bos taurus 57287 R-BTA-5660660 https://reactome.org/PathwayBrowser/#/R-BTA-5660660 p300 acetylates RELA subunit IEA Bos taurus 57287 R-BTA-5682044 https://reactome.org/PathwayBrowser/#/R-BTA-5682044 KAT5 acetylates ATM at DNA DSBs IEA Bos taurus 57287 R-BTA-5682084 https://reactome.org/PathwayBrowser/#/R-BTA-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Bos taurus 57287 R-BTA-5686304 https://reactome.org/PathwayBrowser/#/R-BTA-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Bos taurus 57287 R-BTA-5690042 https://reactome.org/PathwayBrowser/#/R-BTA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 57287 R-BTA-5690043 https://reactome.org/PathwayBrowser/#/R-BTA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 57287 R-BTA-5690046 https://reactome.org/PathwayBrowser/#/R-BTA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Bos taurus 57287 R-BTA-5690066 https://reactome.org/PathwayBrowser/#/R-BTA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 57287 R-BTA-5694494 https://reactome.org/PathwayBrowser/#/R-BTA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Bos taurus 57287 R-BTA-5696004 https://reactome.org/PathwayBrowser/#/R-BTA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Bos taurus 57287 R-BTA-5696007 https://reactome.org/PathwayBrowser/#/R-BTA-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Bos taurus 57287 R-BTA-5696424 https://reactome.org/PathwayBrowser/#/R-BTA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Bos taurus 57287 R-BTA-5696448 https://reactome.org/PathwayBrowser/#/R-BTA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Bos taurus 57287 R-BTA-6792712 https://reactome.org/PathwayBrowser/#/R-BTA-6792712 KAT5 acetylates ATM at shortened telomeres IEA Bos taurus 57287 R-BTA-6800334 https://reactome.org/PathwayBrowser/#/R-BTA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Bos taurus 57287 R-BTA-6805638 https://reactome.org/PathwayBrowser/#/R-BTA-6805638 KAT6A acetylates TP53 IEA Bos taurus 57287 R-BTA-6811508 https://reactome.org/PathwayBrowser/#/R-BTA-6811508 ING2-bound EP300 acetylates TP53 IEA Bos taurus 57287 R-BTA-70542 https://reactome.org/PathwayBrowser/#/R-BTA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Bos taurus 57287 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 57287 R-BTA-70844 https://reactome.org/PathwayBrowser/#/R-BTA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Bos taurus 57287 R-BTA-70881 https://reactome.org/PathwayBrowser/#/R-BTA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Bos taurus 57287 R-BTA-70893 https://reactome.org/PathwayBrowser/#/R-BTA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Bos taurus 57287 R-BTA-70975 https://reactome.org/PathwayBrowser/#/R-BTA-70975 CS acetylates OA to citrate IEA Bos taurus 57287 R-BTA-70997 https://reactome.org/PathwayBrowser/#/R-BTA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Bos taurus 57287 R-BTA-71037 https://reactome.org/PathwayBrowser/#/R-BTA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Bos taurus 57287 R-BTA-71735 https://reactome.org/PathwayBrowser/#/R-BTA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Bos taurus 57287 R-BTA-71775 https://reactome.org/PathwayBrowser/#/R-BTA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Bos taurus 57287 R-BTA-73916 https://reactome.org/PathwayBrowser/#/R-BTA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Bos taurus 57287 R-BTA-73918 https://reactome.org/PathwayBrowser/#/R-BTA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Bos taurus 57287 R-BTA-74181 https://reactome.org/PathwayBrowser/#/R-BTA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Bos taurus 57287 R-BTA-75848 https://reactome.org/PathwayBrowser/#/R-BTA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Bos taurus 57287 R-BTA-75872 https://reactome.org/PathwayBrowser/#/R-BTA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Bos taurus 57287 R-BTA-75879 https://reactome.org/PathwayBrowser/#/R-BTA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Bos taurus 57287 R-BTA-75885 https://reactome.org/PathwayBrowser/#/R-BTA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Bos taurus 57287 R-BTA-75886 https://reactome.org/PathwayBrowser/#/R-BTA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Bos taurus 57287 R-BTA-75900 https://reactome.org/PathwayBrowser/#/R-BTA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Bos taurus 57287 R-BTA-77271 https://reactome.org/PathwayBrowser/#/R-BTA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Bos taurus 57287 R-BTA-77304 https://reactome.org/PathwayBrowser/#/R-BTA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Bos taurus 57287 R-BTA-77309 https://reactome.org/PathwayBrowser/#/R-BTA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Bos taurus 57287 R-BTA-77321 https://reactome.org/PathwayBrowser/#/R-BTA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Bos taurus 57287 R-BTA-77329 https://reactome.org/PathwayBrowser/#/R-BTA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Bos taurus 57287 R-BTA-77340 https://reactome.org/PathwayBrowser/#/R-BTA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Bos taurus 57287 R-BTA-8848215 https://reactome.org/PathwayBrowser/#/R-BTA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Bos taurus 57287 R-BTA-8848580 https://reactome.org/PathwayBrowser/#/R-BTA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Bos taurus 57287 R-BTA-8848582 https://reactome.org/PathwayBrowser/#/R-BTA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Bos taurus 57287 R-BTA-8848585 https://reactome.org/PathwayBrowser/#/R-BTA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Bos taurus 57287 R-BTA-8849345 https://reactome.org/PathwayBrowser/#/R-BTA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Bos taurus 57287 R-BTA-8874745 https://reactome.org/PathwayBrowser/#/R-BTA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Bos taurus 57287 R-BTA-8875071 https://reactome.org/PathwayBrowser/#/R-BTA-8875071 ACSS3 ligates CoA to CH3COO- IEA Bos taurus 57287 R-BTA-8876696 https://reactome.org/PathwayBrowser/#/R-BTA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Bos taurus 57287 R-BTA-8933547 https://reactome.org/PathwayBrowser/#/R-BTA-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Bos taurus 57287 R-BTA-8951966 https://reactome.org/PathwayBrowser/#/R-BTA-8951966 EP300 acetylates RUNX3 IEA Bos taurus 57287 R-BTA-8954468 https://reactome.org/PathwayBrowser/#/R-BTA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Bos taurus 57287 R-BTA-9021072 https://reactome.org/PathwayBrowser/#/R-BTA-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Bos taurus 57287 R-BTA-9620515 https://reactome.org/PathwayBrowser/#/R-BTA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Bos taurus 57287 R-BTA-9647982 https://reactome.org/PathwayBrowser/#/R-BTA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Bos taurus 57287 R-BTA-9701531 https://reactome.org/PathwayBrowser/#/R-BTA-9701531 p-Y705,S727 STAT3 is acetylated IEA Bos taurus 57287 R-BTA-9734535 https://reactome.org/PathwayBrowser/#/R-BTA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Bos taurus 57287 R-BTA-9749971 https://reactome.org/PathwayBrowser/#/R-BTA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Bos taurus 57287 R-BTA-9750001 https://reactome.org/PathwayBrowser/#/R-BTA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Bos taurus 57287 R-BTA-9753676 https://reactome.org/PathwayBrowser/#/R-BTA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Bos taurus 57287 R-BTA-9760081 https://reactome.org/PathwayBrowser/#/R-BTA-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Bos taurus 57287 R-BTA-9825747 https://reactome.org/PathwayBrowser/#/R-BTA-9825747 CREBBP acetylates HINT1 dimer IEA Bos taurus 57287 R-BTA-9837333 https://reactome.org/PathwayBrowser/#/R-BTA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Bos taurus 57287 R-BTA-9837337 https://reactome.org/PathwayBrowser/#/R-BTA-9837337 DCAKD phosphorylates DP-CoA IEA Bos taurus 57287 R-BTA-9853512 https://reactome.org/PathwayBrowser/#/R-BTA-9853512 DLST transfers succinyl to CoA IEA Bos taurus 57287 R-BTA-9854415 https://reactome.org/PathwayBrowser/#/R-BTA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Bos taurus 57287 R-BTA-9861667 https://reactome.org/PathwayBrowser/#/R-BTA-9861667 DLAT trimer transfers acetyl to CoA IEA Bos taurus 57287 R-CEL-1482533 https://reactome.org/PathwayBrowser/#/R-CEL-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Caenorhabditis elegans 57287 R-CEL-1482539 https://reactome.org/PathwayBrowser/#/R-CEL-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Caenorhabditis elegans 57287 R-CEL-1482546 https://reactome.org/PathwayBrowser/#/R-CEL-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Caenorhabditis elegans 57287 R-CEL-1482547 https://reactome.org/PathwayBrowser/#/R-CEL-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Caenorhabditis elegans 57287 R-CEL-1482548 https://reactome.org/PathwayBrowser/#/R-CEL-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Caenorhabditis elegans 57287 R-CEL-1482598 https://reactome.org/PathwayBrowser/#/R-CEL-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Caenorhabditis elegans 57287 R-CEL-1482626 https://reactome.org/PathwayBrowser/#/R-CEL-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Caenorhabditis elegans 57287 R-CEL-1482635 https://reactome.org/PathwayBrowser/#/R-CEL-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Caenorhabditis elegans 57287 R-CEL-1482636 https://reactome.org/PathwayBrowser/#/R-CEL-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Caenorhabditis elegans 57287 R-CEL-1482646 https://reactome.org/PathwayBrowser/#/R-CEL-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Caenorhabditis elegans 57287 R-CEL-1482667 https://reactome.org/PathwayBrowser/#/R-CEL-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Caenorhabditis elegans 57287 R-CEL-1482689 https://reactome.org/PathwayBrowser/#/R-CEL-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Caenorhabditis elegans 57287 R-CEL-1482691 https://reactome.org/PathwayBrowser/#/R-CEL-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Caenorhabditis elegans 57287 R-CEL-1482695 https://reactome.org/PathwayBrowser/#/R-CEL-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Caenorhabditis elegans 57287 R-CEL-1482775 https://reactome.org/PathwayBrowser/#/R-CEL-1482775 MLCL is acylated to CL by HADH (IM) IEA Caenorhabditis elegans 57287 R-CEL-1482861 https://reactome.org/PathwayBrowser/#/R-CEL-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Caenorhabditis elegans 57287 R-CEL-1482867 https://reactome.org/PathwayBrowser/#/R-CEL-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Caenorhabditis elegans 57287 R-CEL-1482889 https://reactome.org/PathwayBrowser/#/R-CEL-1482889 DAG is acylated to TAG by DGAT1/2 IEA Caenorhabditis elegans 57287 R-CEL-1483002 https://reactome.org/PathwayBrowser/#/R-CEL-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Caenorhabditis elegans 57287 R-CEL-159425 https://reactome.org/PathwayBrowser/#/R-CEL-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 57287 R-CEL-159431 https://reactome.org/PathwayBrowser/#/R-CEL-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Caenorhabditis elegans 57287 R-CEL-159566 https://reactome.org/PathwayBrowser/#/R-CEL-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Caenorhabditis elegans 57287 R-CEL-159574 https://reactome.org/PathwayBrowser/#/R-CEL-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Caenorhabditis elegans 57287 R-CEL-162683 https://reactome.org/PathwayBrowser/#/R-CEL-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Caenorhabditis elegans 57287 R-CEL-191323 https://reactome.org/PathwayBrowser/#/R-CEL-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Caenorhabditis elegans 57287 R-CEL-191352 https://reactome.org/PathwayBrowser/#/R-CEL-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Caenorhabditis elegans 57287 R-CEL-192137 https://reactome.org/PathwayBrowser/#/R-CEL-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 57287 R-CEL-192312 https://reactome.org/PathwayBrowser/#/R-CEL-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Caenorhabditis elegans 57287 R-CEL-193385 https://reactome.org/PathwayBrowser/#/R-CEL-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Caenorhabditis elegans 57287 R-CEL-193401 https://reactome.org/PathwayBrowser/#/R-CEL-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 57287 R-CEL-193407 https://reactome.org/PathwayBrowser/#/R-CEL-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 57287 R-CEL-193424 https://reactome.org/PathwayBrowser/#/R-CEL-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 57287 R-CEL-193491 https://reactome.org/PathwayBrowser/#/R-CEL-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Caenorhabditis elegans 57287 R-CEL-193711 https://reactome.org/PathwayBrowser/#/R-CEL-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 57287 R-CEL-193727 https://reactome.org/PathwayBrowser/#/R-CEL-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 57287 R-CEL-193743 https://reactome.org/PathwayBrowser/#/R-CEL-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 57287 R-CEL-193766 https://reactome.org/PathwayBrowser/#/R-CEL-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 57287 R-CEL-196773 https://reactome.org/PathwayBrowser/#/R-CEL-196773 COASY phosphorylates DP-CoA IEA Caenorhabditis elegans 57287 R-CEL-199202 https://reactome.org/PathwayBrowser/#/R-CEL-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Caenorhabditis elegans 57287 R-CEL-200406 https://reactome.org/PathwayBrowser/#/R-CEL-200406 CPT1A,B transfers PALM to CAR IEA Caenorhabditis elegans 57287 R-CEL-200410 https://reactome.org/PathwayBrowser/#/R-CEL-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Caenorhabditis elegans 57287 R-CEL-201035 https://reactome.org/PathwayBrowser/#/R-CEL-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Caenorhabditis elegans 57287 R-CEL-2046088 https://reactome.org/PathwayBrowser/#/R-CEL-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-2046094 https://reactome.org/PathwayBrowser/#/R-CEL-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-2066779 https://reactome.org/PathwayBrowser/#/R-CEL-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Caenorhabditis elegans 57287 R-CEL-2468039 https://reactome.org/PathwayBrowser/#/R-CEL-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Caenorhabditis elegans 57287 R-CEL-2473152 https://reactome.org/PathwayBrowser/#/R-CEL-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Caenorhabditis elegans 57287 R-CEL-264622 https://reactome.org/PathwayBrowser/#/R-CEL-264622 Cho is acetylated to AcCho by CHAT IEA Caenorhabditis elegans 57287 R-CEL-3318413 https://reactome.org/PathwayBrowser/#/R-CEL-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Caenorhabditis elegans 57287 R-CEL-3318415 https://reactome.org/PathwayBrowser/#/R-CEL-3318415 ATF2 acetylates histone H2B, H4 IEA Caenorhabditis elegans 57287 R-CEL-3318486 https://reactome.org/PathwayBrowser/#/R-CEL-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Caenorhabditis elegans 57287 R-CEL-351207 https://reactome.org/PathwayBrowser/#/R-CEL-351207 Spermine => N-acetylated spermine IEA Caenorhabditis elegans 57287 R-CEL-351208 https://reactome.org/PathwayBrowser/#/R-CEL-351208 Spermidine => N-acetylated spermidine IEA Caenorhabditis elegans 57287 R-CEL-3662318 https://reactome.org/PathwayBrowser/#/R-CEL-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Caenorhabditis elegans 57287 R-CEL-389622 https://reactome.org/PathwayBrowser/#/R-CEL-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 57287 R-CEL-389632 https://reactome.org/PathwayBrowser/#/R-CEL-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 57287 R-CEL-390281 https://reactome.org/PathwayBrowser/#/R-CEL-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Caenorhabditis elegans 57287 R-CEL-390284 https://reactome.org/PathwayBrowser/#/R-CEL-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Caenorhabditis elegans 57287 R-CEL-390291 https://reactome.org/PathwayBrowser/#/R-CEL-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Caenorhabditis elegans 57287 R-CEL-390304 https://reactome.org/PathwayBrowser/#/R-CEL-390304 acetyl-CoA + H2O => acetate + CoASH IEA Caenorhabditis elegans 57287 R-CEL-390425 https://reactome.org/PathwayBrowser/#/R-CEL-390425 FAR1 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 57287 R-CEL-390438 https://reactome.org/PathwayBrowser/#/R-CEL-390438 FAR2 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 57287 R-CEL-428185 https://reactome.org/PathwayBrowser/#/R-CEL-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Caenorhabditis elegans 57287 R-CEL-434382 https://reactome.org/PathwayBrowser/#/R-CEL-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Caenorhabditis elegans 57287 R-CEL-449734 https://reactome.org/PathwayBrowser/#/R-CEL-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Caenorhabditis elegans 57287 R-CEL-5250938 https://reactome.org/PathwayBrowser/#/R-CEL-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Caenorhabditis elegans 57287 R-CEL-548800 https://reactome.org/PathwayBrowser/#/R-CEL-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Caenorhabditis elegans 57287 R-CEL-548814 https://reactome.org/PathwayBrowser/#/R-CEL-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Caenorhabditis elegans 57287 R-CEL-548843 https://reactome.org/PathwayBrowser/#/R-CEL-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Caenorhabditis elegans 57287 R-CEL-549112 https://reactome.org/PathwayBrowser/#/R-CEL-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Caenorhabditis elegans 57287 R-CEL-549192 https://reactome.org/PathwayBrowser/#/R-CEL-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Caenorhabditis elegans 57287 R-CEL-5690042 https://reactome.org/PathwayBrowser/#/R-CEL-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 57287 R-CEL-5690043 https://reactome.org/PathwayBrowser/#/R-CEL-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 57287 R-CEL-5690066 https://reactome.org/PathwayBrowser/#/R-CEL-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 57287 R-CEL-5694494 https://reactome.org/PathwayBrowser/#/R-CEL-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Caenorhabditis elegans 57287 R-CEL-5696004 https://reactome.org/PathwayBrowser/#/R-CEL-5696004 ACSF2 ligates CoA-SH to MCFA IEA Caenorhabditis elegans 57287 R-CEL-5696424 https://reactome.org/PathwayBrowser/#/R-CEL-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Caenorhabditis elegans 57287 R-CEL-5696448 https://reactome.org/PathwayBrowser/#/R-CEL-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Caenorhabditis elegans 57287 R-CEL-6800334 https://reactome.org/PathwayBrowser/#/R-CEL-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Caenorhabditis elegans 57287 R-CEL-6805638 https://reactome.org/PathwayBrowser/#/R-CEL-6805638 KAT6A acetylates TP53 IEA Caenorhabditis elegans 57287 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 57287 R-CEL-70844 https://reactome.org/PathwayBrowser/#/R-CEL-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-70881 https://reactome.org/PathwayBrowser/#/R-CEL-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Caenorhabditis elegans 57287 R-CEL-70893 https://reactome.org/PathwayBrowser/#/R-CEL-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 57287 R-CEL-70975 https://reactome.org/PathwayBrowser/#/R-CEL-70975 CS acetylates OA to citrate IEA Caenorhabditis elegans 57287 R-CEL-70997 https://reactome.org/PathwayBrowser/#/R-CEL-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-71037 https://reactome.org/PathwayBrowser/#/R-CEL-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 57287 R-CEL-71735 https://reactome.org/PathwayBrowser/#/R-CEL-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Caenorhabditis elegans 57287 R-CEL-71775 https://reactome.org/PathwayBrowser/#/R-CEL-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-73916 https://reactome.org/PathwayBrowser/#/R-CEL-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Caenorhabditis elegans 57287 R-CEL-73918 https://reactome.org/PathwayBrowser/#/R-CEL-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Caenorhabditis elegans 57287 R-CEL-74181 https://reactome.org/PathwayBrowser/#/R-CEL-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-75848 https://reactome.org/PathwayBrowser/#/R-CEL-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Caenorhabditis elegans 57287 R-CEL-75872 https://reactome.org/PathwayBrowser/#/R-CEL-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Caenorhabditis elegans 57287 R-CEL-75879 https://reactome.org/PathwayBrowser/#/R-CEL-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Caenorhabditis elegans 57287 R-CEL-75885 https://reactome.org/PathwayBrowser/#/R-CEL-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Caenorhabditis elegans 57287 R-CEL-75886 https://reactome.org/PathwayBrowser/#/R-CEL-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Caenorhabditis elegans 57287 R-CEL-75900 https://reactome.org/PathwayBrowser/#/R-CEL-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Caenorhabditis elegans 57287 R-CEL-77271 https://reactome.org/PathwayBrowser/#/R-CEL-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-77304 https://reactome.org/PathwayBrowser/#/R-CEL-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-77309 https://reactome.org/PathwayBrowser/#/R-CEL-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-77321 https://reactome.org/PathwayBrowser/#/R-CEL-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-77329 https://reactome.org/PathwayBrowser/#/R-CEL-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-77340 https://reactome.org/PathwayBrowser/#/R-CEL-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Caenorhabditis elegans 57287 R-CEL-8848580 https://reactome.org/PathwayBrowser/#/R-CEL-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Caenorhabditis elegans 57287 R-CEL-8848582 https://reactome.org/PathwayBrowser/#/R-CEL-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Caenorhabditis elegans 57287 R-CEL-8848585 https://reactome.org/PathwayBrowser/#/R-CEL-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Caenorhabditis elegans 57287 R-CEL-8874745 https://reactome.org/PathwayBrowser/#/R-CEL-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Caenorhabditis elegans 57287 R-CEL-8876696 https://reactome.org/PathwayBrowser/#/R-CEL-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Caenorhabditis elegans 57287 R-CEL-8951966 https://reactome.org/PathwayBrowser/#/R-CEL-8951966 EP300 acetylates RUNX3 IEA Caenorhabditis elegans 57287 R-CEL-9620515 https://reactome.org/PathwayBrowser/#/R-CEL-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Caenorhabditis elegans 57287 R-CEL-9647982 https://reactome.org/PathwayBrowser/#/R-CEL-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Caenorhabditis elegans 57287 R-CEL-9701531 https://reactome.org/PathwayBrowser/#/R-CEL-9701531 p-Y705,S727 STAT3 is acetylated IEA Caenorhabditis elegans 57287 R-CEL-9734535 https://reactome.org/PathwayBrowser/#/R-CEL-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Caenorhabditis elegans 57287 R-CEL-9750001 https://reactome.org/PathwayBrowser/#/R-CEL-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Caenorhabditis elegans 57287 R-CEL-9760081 https://reactome.org/PathwayBrowser/#/R-CEL-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Caenorhabditis elegans 57287 R-CEL-9825747 https://reactome.org/PathwayBrowser/#/R-CEL-9825747 CREBBP acetylates HINT1 dimer IEA Caenorhabditis elegans 57287 R-CEL-9837333 https://reactome.org/PathwayBrowser/#/R-CEL-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Caenorhabditis elegans 57287 R-CEL-9837337 https://reactome.org/PathwayBrowser/#/R-CEL-9837337 DCAKD phosphorylates DP-CoA IEA Caenorhabditis elegans 57287 R-CEL-9853512 https://reactome.org/PathwayBrowser/#/R-CEL-9853512 DLST transfers succinyl to CoA IEA Caenorhabditis elegans 57287 R-CEL-9854415 https://reactome.org/PathwayBrowser/#/R-CEL-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Caenorhabditis elegans 57287 R-CEL-9861667 https://reactome.org/PathwayBrowser/#/R-CEL-9861667 DLAT trimer transfers acetyl to CoA IEA Caenorhabditis elegans 57287 R-CFA-1482533 https://reactome.org/PathwayBrowser/#/R-CFA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Canis familiaris 57287 R-CFA-1482539 https://reactome.org/PathwayBrowser/#/R-CFA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Canis familiaris 57287 R-CFA-1482547 https://reactome.org/PathwayBrowser/#/R-CFA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Canis familiaris 57287 R-CFA-1482548 https://reactome.org/PathwayBrowser/#/R-CFA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Canis familiaris 57287 R-CFA-1482598 https://reactome.org/PathwayBrowser/#/R-CFA-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Canis familiaris 57287 R-CFA-1482626 https://reactome.org/PathwayBrowser/#/R-CFA-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Canis familiaris 57287 R-CFA-1482635 https://reactome.org/PathwayBrowser/#/R-CFA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Canis familiaris 57287 R-CFA-1482636 https://reactome.org/PathwayBrowser/#/R-CFA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Canis familiaris 57287 R-CFA-1482646 https://reactome.org/PathwayBrowser/#/R-CFA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Canis familiaris 57287 R-CFA-1482667 https://reactome.org/PathwayBrowser/#/R-CFA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Canis familiaris 57287 R-CFA-1482691 https://reactome.org/PathwayBrowser/#/R-CFA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Canis familiaris 57287 R-CFA-1482695 https://reactome.org/PathwayBrowser/#/R-CFA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Canis familiaris 57287 R-CFA-1482775 https://reactome.org/PathwayBrowser/#/R-CFA-1482775 MLCL is acylated to CL by HADH (IM) IEA Canis familiaris 57287 R-CFA-1482861 https://reactome.org/PathwayBrowser/#/R-CFA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Canis familiaris 57287 R-CFA-1482867 https://reactome.org/PathwayBrowser/#/R-CFA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Canis familiaris 57287 R-CFA-1482889 https://reactome.org/PathwayBrowser/#/R-CFA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Canis familiaris 57287 R-CFA-1483002 https://reactome.org/PathwayBrowser/#/R-CFA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Canis familiaris 57287 R-CFA-159425 https://reactome.org/PathwayBrowser/#/R-CFA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 57287 R-CFA-159431 https://reactome.org/PathwayBrowser/#/R-CFA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Canis familiaris 57287 R-CFA-159443 https://reactome.org/PathwayBrowser/#/R-CFA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 57287 R-CFA-159566 https://reactome.org/PathwayBrowser/#/R-CFA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Canis familiaris 57287 R-CFA-159567 https://reactome.org/PathwayBrowser/#/R-CFA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Canis familiaris 57287 R-CFA-159574 https://reactome.org/PathwayBrowser/#/R-CFA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Canis familiaris 57287 R-CFA-162683 https://reactome.org/PathwayBrowser/#/R-CFA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Canis familiaris 57287 R-CFA-1678660 https://reactome.org/PathwayBrowser/#/R-CFA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Canis familiaris 57287 R-CFA-177157 https://reactome.org/PathwayBrowser/#/R-CFA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Canis familiaris 57287 R-CFA-189442 https://reactome.org/PathwayBrowser/#/R-CFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Canis familiaris 57287 R-CFA-191323 https://reactome.org/PathwayBrowser/#/R-CFA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Canis familiaris 57287 R-CFA-191352 https://reactome.org/PathwayBrowser/#/R-CFA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Canis familiaris 57287 R-CFA-192137 https://reactome.org/PathwayBrowser/#/R-CFA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 57287 R-CFA-192312 https://reactome.org/PathwayBrowser/#/R-CFA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Canis familiaris 57287 R-CFA-192341 https://reactome.org/PathwayBrowser/#/R-CFA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Canis familiaris 57287 R-CFA-193385 https://reactome.org/PathwayBrowser/#/R-CFA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Canis familiaris 57287 R-CFA-193401 https://reactome.org/PathwayBrowser/#/R-CFA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 57287 R-CFA-193407 https://reactome.org/PathwayBrowser/#/R-CFA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 57287 R-CFA-193424 https://reactome.org/PathwayBrowser/#/R-CFA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 57287 R-CFA-193491 https://reactome.org/PathwayBrowser/#/R-CFA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Canis familiaris 57287 R-CFA-193533 https://reactome.org/PathwayBrowser/#/R-CFA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Canis familiaris 57287 R-CFA-193711 https://reactome.org/PathwayBrowser/#/R-CFA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 57287 R-CFA-193727 https://reactome.org/PathwayBrowser/#/R-CFA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 57287 R-CFA-193743 https://reactome.org/PathwayBrowser/#/R-CFA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 57287 R-CFA-193766 https://reactome.org/PathwayBrowser/#/R-CFA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 57287 R-CFA-196773 https://reactome.org/PathwayBrowser/#/R-CFA-196773 COASY phosphorylates DP-CoA IEA Canis familiaris 57287 R-CFA-196857 https://reactome.org/PathwayBrowser/#/R-CFA-196857 PANK2 phosphorylates PanK IEA Canis familiaris 57287 R-CFA-199202 https://reactome.org/PathwayBrowser/#/R-CFA-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Canis familiaris 57287 R-CFA-199216 https://reactome.org/PathwayBrowser/#/R-CFA-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Canis familiaris 57287 R-CFA-200406 https://reactome.org/PathwayBrowser/#/R-CFA-200406 CPT1A,B transfers PALM to CAR IEA Canis familiaris 57287 R-CFA-200410 https://reactome.org/PathwayBrowser/#/R-CFA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Canis familiaris 57287 R-CFA-201035 https://reactome.org/PathwayBrowser/#/R-CFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Canis familiaris 57287 R-CFA-2046083 https://reactome.org/PathwayBrowser/#/R-CFA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Canis familiaris 57287 R-CFA-2046085 https://reactome.org/PathwayBrowser/#/R-CFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Canis familiaris 57287 R-CFA-2046088 https://reactome.org/PathwayBrowser/#/R-CFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Canis familiaris 57287 R-CFA-2046090 https://reactome.org/PathwayBrowser/#/R-CFA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 57287 R-CFA-2046094 https://reactome.org/PathwayBrowser/#/R-CFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Canis familiaris 57287 R-CFA-2046095 https://reactome.org/PathwayBrowser/#/R-CFA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Canis familiaris 57287 R-CFA-2046098 https://reactome.org/PathwayBrowser/#/R-CFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Canis familiaris 57287 R-CFA-2046100 https://reactome.org/PathwayBrowser/#/R-CFA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Canis familiaris 57287 R-CFA-2066779 https://reactome.org/PathwayBrowser/#/R-CFA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Canis familiaris 57287 R-CFA-2066781 https://reactome.org/PathwayBrowser/#/R-CFA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Canis familiaris 57287 R-CFA-2066788 https://reactome.org/PathwayBrowser/#/R-CFA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Canis familiaris 57287 R-CFA-2090085 https://reactome.org/PathwayBrowser/#/R-CFA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Canis familiaris 57287 R-CFA-209792 https://reactome.org/PathwayBrowser/#/R-CFA-209792 N-acetylation of serotonin IEA Canis familiaris 57287 R-CFA-2465919 https://reactome.org/PathwayBrowser/#/R-CFA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Canis familiaris 57287 R-CFA-2468039 https://reactome.org/PathwayBrowser/#/R-CFA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Canis familiaris 57287 R-CFA-2473152 https://reactome.org/PathwayBrowser/#/R-CFA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Canis familiaris 57287 R-CFA-2534087 https://reactome.org/PathwayBrowser/#/R-CFA-2534087 NMT1/2 transfer MYS to GNAT1 IEA Canis familiaris 57287 R-CFA-2545203 https://reactome.org/PathwayBrowser/#/R-CFA-2545203 Deacetylation of cleaved cohesin IEA Canis familiaris 57287 R-CFA-2545253 https://reactome.org/PathwayBrowser/#/R-CFA-2545253 Deacetylation of cohesin IEA Canis familiaris 57287 R-CFA-264622 https://reactome.org/PathwayBrowser/#/R-CFA-264622 Cho is acetylated to AcCho by CHAT IEA Canis familiaris 57287 R-CFA-3318413 https://reactome.org/PathwayBrowser/#/R-CFA-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Canis familiaris 57287 R-CFA-3318415 https://reactome.org/PathwayBrowser/#/R-CFA-3318415 ATF2 acetylates histone H2B, H4 IEA Canis familiaris 57287 R-CFA-3318486 https://reactome.org/PathwayBrowser/#/R-CFA-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Canis familiaris 57287 R-CFA-3321805 https://reactome.org/PathwayBrowser/#/R-CFA-3321805 NSL acetylates histone H4 IEA Canis familiaris 57287 R-CFA-3321883 https://reactome.org/PathwayBrowser/#/R-CFA-3321883 MSL acetylates histone H4 IEA Canis familiaris 57287 R-CFA-3371554 https://reactome.org/PathwayBrowser/#/R-CFA-3371554 HSF1 acetylation at Lys80 IEA Canis familiaris 57287 R-CFA-351207 https://reactome.org/PathwayBrowser/#/R-CFA-351207 Spermine => N-acetylated spermine IEA Canis familiaris 57287 R-CFA-351208 https://reactome.org/PathwayBrowser/#/R-CFA-351208 Spermidine => N-acetylated spermidine IEA Canis familiaris 57287 R-CFA-3662335 https://reactome.org/PathwayBrowser/#/R-CFA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Canis familiaris 57287 R-CFA-389622 https://reactome.org/PathwayBrowser/#/R-CFA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 57287 R-CFA-389632 https://reactome.org/PathwayBrowser/#/R-CFA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 57287 R-CFA-390224 https://reactome.org/PathwayBrowser/#/R-CFA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Canis familiaris 57287 R-CFA-390250 https://reactome.org/PathwayBrowser/#/R-CFA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Canis familiaris 57287 R-CFA-390281 https://reactome.org/PathwayBrowser/#/R-CFA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Canis familiaris 57287 R-CFA-390284 https://reactome.org/PathwayBrowser/#/R-CFA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Canis familiaris 57287 R-CFA-390291 https://reactome.org/PathwayBrowser/#/R-CFA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Canis familiaris 57287 R-CFA-390304 https://reactome.org/PathwayBrowser/#/R-CFA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Canis familiaris 57287 R-CFA-390425 https://reactome.org/PathwayBrowser/#/R-CFA-390425 FAR1 reduces PalmCoA to HXOL IEA Canis familiaris 57287 R-CFA-390438 https://reactome.org/PathwayBrowser/#/R-CFA-390438 FAR2 reduces PalmCoA to HXOL IEA Canis familiaris 57287 R-CFA-428127 https://reactome.org/PathwayBrowser/#/R-CFA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Canis familiaris 57287 R-CFA-428185 https://reactome.org/PathwayBrowser/#/R-CFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Canis familiaris 57287 R-CFA-434382 https://reactome.org/PathwayBrowser/#/R-CFA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Canis familiaris 57287 R-CFA-449734 https://reactome.org/PathwayBrowser/#/R-CFA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Canis familiaris 57287 R-CFA-449911 https://reactome.org/PathwayBrowser/#/R-CFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Canis familiaris 57287 R-CFA-5250938 https://reactome.org/PathwayBrowser/#/R-CFA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Canis familiaris 57287 R-CFA-5358343 https://reactome.org/PathwayBrowser/#/R-CFA-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Canis familiaris 57287 R-CFA-548800 https://reactome.org/PathwayBrowser/#/R-CFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Canis familiaris 57287 R-CFA-548814 https://reactome.org/PathwayBrowser/#/R-CFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Canis familiaris 57287 R-CFA-548815 https://reactome.org/PathwayBrowser/#/R-CFA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Canis familiaris 57287 R-CFA-548843 https://reactome.org/PathwayBrowser/#/R-CFA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Canis familiaris 57287 R-CFA-549112 https://reactome.org/PathwayBrowser/#/R-CFA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Canis familiaris 57287 R-CFA-549192 https://reactome.org/PathwayBrowser/#/R-CFA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Canis familiaris 57287 R-CFA-5618328 https://reactome.org/PathwayBrowser/#/R-CFA-5618328 ATAT acetylates microtubules IEA Canis familiaris 57287 R-CFA-5618331 https://reactome.org/PathwayBrowser/#/R-CFA-5618331 HDAC6 deacetylates microtubules IEA Canis familiaris 57287 R-CFA-5628871 https://reactome.org/PathwayBrowser/#/R-CFA-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Canis familiaris 57287 R-CFA-5660660 https://reactome.org/PathwayBrowser/#/R-CFA-5660660 p300 acetylates RELA subunit IEA Canis familiaris 57287 R-CFA-5682044 https://reactome.org/PathwayBrowser/#/R-CFA-5682044 KAT5 acetylates ATM at DNA DSBs IEA Canis familiaris 57287 R-CFA-5682084 https://reactome.org/PathwayBrowser/#/R-CFA-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Canis familiaris 57287 R-CFA-5686304 https://reactome.org/PathwayBrowser/#/R-CFA-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Canis familiaris 57287 R-CFA-5690042 https://reactome.org/PathwayBrowser/#/R-CFA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 57287 R-CFA-5690043 https://reactome.org/PathwayBrowser/#/R-CFA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 57287 R-CFA-5690046 https://reactome.org/PathwayBrowser/#/R-CFA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Canis familiaris 57287 R-CFA-5690066 https://reactome.org/PathwayBrowser/#/R-CFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 57287 R-CFA-5695957 https://reactome.org/PathwayBrowser/#/R-CFA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Canis familiaris 57287 R-CFA-5696004 https://reactome.org/PathwayBrowser/#/R-CFA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Canis familiaris 57287 R-CFA-5696424 https://reactome.org/PathwayBrowser/#/R-CFA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Canis familiaris 57287 R-CFA-5696448 https://reactome.org/PathwayBrowser/#/R-CFA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Canis familiaris 57287 R-CFA-6792712 https://reactome.org/PathwayBrowser/#/R-CFA-6792712 KAT5 acetylates ATM at shortened telomeres IEA Canis familiaris 57287 R-CFA-6800334 https://reactome.org/PathwayBrowser/#/R-CFA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Canis familiaris 57287 R-CFA-6805638 https://reactome.org/PathwayBrowser/#/R-CFA-6805638 KAT6A acetylates TP53 IEA Canis familiaris 57287 R-CFA-6811508 https://reactome.org/PathwayBrowser/#/R-CFA-6811508 ING2-bound EP300 acetylates TP53 IEA Canis familiaris 57287 R-CFA-70542 https://reactome.org/PathwayBrowser/#/R-CFA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Canis familiaris 57287 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 57287 R-CFA-70844 https://reactome.org/PathwayBrowser/#/R-CFA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Canis familiaris 57287 R-CFA-70881 https://reactome.org/PathwayBrowser/#/R-CFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Canis familiaris 57287 R-CFA-70893 https://reactome.org/PathwayBrowser/#/R-CFA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Canis familiaris 57287 R-CFA-70975 https://reactome.org/PathwayBrowser/#/R-CFA-70975 CS acetylates OA to citrate IEA Canis familiaris 57287 R-CFA-70997 https://reactome.org/PathwayBrowser/#/R-CFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Canis familiaris 57287 R-CFA-71037 https://reactome.org/PathwayBrowser/#/R-CFA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Canis familiaris 57287 R-CFA-71735 https://reactome.org/PathwayBrowser/#/R-CFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Canis familiaris 57287 R-CFA-71775 https://reactome.org/PathwayBrowser/#/R-CFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Canis familiaris 57287 R-CFA-73916 https://reactome.org/PathwayBrowser/#/R-CFA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Canis familiaris 57287 R-CFA-73918 https://reactome.org/PathwayBrowser/#/R-CFA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Canis familiaris 57287 R-CFA-74181 https://reactome.org/PathwayBrowser/#/R-CFA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Canis familiaris 57287 R-CFA-75848 https://reactome.org/PathwayBrowser/#/R-CFA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Canis familiaris 57287 R-CFA-75872 https://reactome.org/PathwayBrowser/#/R-CFA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Canis familiaris 57287 R-CFA-75879 https://reactome.org/PathwayBrowser/#/R-CFA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Canis familiaris 57287 R-CFA-75885 https://reactome.org/PathwayBrowser/#/R-CFA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Canis familiaris 57287 R-CFA-75886 https://reactome.org/PathwayBrowser/#/R-CFA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Canis familiaris 57287 R-CFA-75900 https://reactome.org/PathwayBrowser/#/R-CFA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Canis familiaris 57287 R-CFA-77271 https://reactome.org/PathwayBrowser/#/R-CFA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Canis familiaris 57287 R-CFA-77304 https://reactome.org/PathwayBrowser/#/R-CFA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Canis familiaris 57287 R-CFA-77309 https://reactome.org/PathwayBrowser/#/R-CFA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Canis familiaris 57287 R-CFA-77321 https://reactome.org/PathwayBrowser/#/R-CFA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Canis familiaris 57287 R-CFA-77329 https://reactome.org/PathwayBrowser/#/R-CFA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Canis familiaris 57287 R-CFA-77340 https://reactome.org/PathwayBrowser/#/R-CFA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Canis familiaris 57287 R-CFA-8848215 https://reactome.org/PathwayBrowser/#/R-CFA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Canis familiaris 57287 R-CFA-8848582 https://reactome.org/PathwayBrowser/#/R-CFA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Canis familiaris 57287 R-CFA-8848585 https://reactome.org/PathwayBrowser/#/R-CFA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Canis familiaris 57287 R-CFA-8849345 https://reactome.org/PathwayBrowser/#/R-CFA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Canis familiaris 57287 R-CFA-8874745 https://reactome.org/PathwayBrowser/#/R-CFA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Canis familiaris 57287 R-CFA-8875071 https://reactome.org/PathwayBrowser/#/R-CFA-8875071 ACSS3 ligates CoA to CH3COO- IEA Canis familiaris 57287 R-CFA-8876696 https://reactome.org/PathwayBrowser/#/R-CFA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Canis familiaris 57287 R-CFA-8933547 https://reactome.org/PathwayBrowser/#/R-CFA-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Canis familiaris 57287 R-CFA-8951966 https://reactome.org/PathwayBrowser/#/R-CFA-8951966 EP300 acetylates RUNX3 IEA Canis familiaris 57287 R-CFA-8954468 https://reactome.org/PathwayBrowser/#/R-CFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Canis familiaris 57287 R-CFA-9021072 https://reactome.org/PathwayBrowser/#/R-CFA-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Canis familiaris 57287 R-CFA-9620515 https://reactome.org/PathwayBrowser/#/R-CFA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Canis familiaris 57287 R-CFA-9647982 https://reactome.org/PathwayBrowser/#/R-CFA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Canis familiaris 57287 R-CFA-9701531 https://reactome.org/PathwayBrowser/#/R-CFA-9701531 p-Y705,S727 STAT3 is acetylated IEA Canis familiaris 57287 R-CFA-9734535 https://reactome.org/PathwayBrowser/#/R-CFA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Canis familiaris 57287 R-CFA-9749971 https://reactome.org/PathwayBrowser/#/R-CFA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Canis familiaris 57287 R-CFA-9750001 https://reactome.org/PathwayBrowser/#/R-CFA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Canis familiaris 57287 R-CFA-9760081 https://reactome.org/PathwayBrowser/#/R-CFA-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Canis familiaris 57287 R-CFA-9825747 https://reactome.org/PathwayBrowser/#/R-CFA-9825747 CREBBP acetylates HINT1 dimer IEA Canis familiaris 57287 R-CFA-9837333 https://reactome.org/PathwayBrowser/#/R-CFA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Canis familiaris 57287 R-CFA-9837337 https://reactome.org/PathwayBrowser/#/R-CFA-9837337 DCAKD phosphorylates DP-CoA IEA Canis familiaris 57287 R-CFA-9853512 https://reactome.org/PathwayBrowser/#/R-CFA-9853512 DLST transfers succinyl to CoA IEA Canis familiaris 57287 R-CFA-9854415 https://reactome.org/PathwayBrowser/#/R-CFA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Canis familiaris 57287 R-CFA-9861667 https://reactome.org/PathwayBrowser/#/R-CFA-9861667 DLAT trimer transfers acetyl to CoA IEA Canis familiaris 57287 R-DDI-1482533 https://reactome.org/PathwayBrowser/#/R-DDI-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Dictyostelium discoideum 57287 R-DDI-1482539 https://reactome.org/PathwayBrowser/#/R-DDI-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Dictyostelium discoideum 57287 R-DDI-1482547 https://reactome.org/PathwayBrowser/#/R-DDI-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Dictyostelium discoideum 57287 R-DDI-1482548 https://reactome.org/PathwayBrowser/#/R-DDI-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Dictyostelium discoideum 57287 R-DDI-1482598 https://reactome.org/PathwayBrowser/#/R-DDI-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Dictyostelium discoideum 57287 R-DDI-1482626 https://reactome.org/PathwayBrowser/#/R-DDI-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Dictyostelium discoideum 57287 R-DDI-1482635 https://reactome.org/PathwayBrowser/#/R-DDI-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Dictyostelium discoideum 57287 R-DDI-1482636 https://reactome.org/PathwayBrowser/#/R-DDI-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Dictyostelium discoideum 57287 R-DDI-1482646 https://reactome.org/PathwayBrowser/#/R-DDI-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Dictyostelium discoideum 57287 R-DDI-1482667 https://reactome.org/PathwayBrowser/#/R-DDI-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Dictyostelium discoideum 57287 R-DDI-1482691 https://reactome.org/PathwayBrowser/#/R-DDI-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Dictyostelium discoideum 57287 R-DDI-1482861 https://reactome.org/PathwayBrowser/#/R-DDI-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Dictyostelium discoideum 57287 R-DDI-1482867 https://reactome.org/PathwayBrowser/#/R-DDI-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Dictyostelium discoideum 57287 R-DDI-1482889 https://reactome.org/PathwayBrowser/#/R-DDI-1482889 DAG is acylated to TAG by DGAT1/2 IEA Dictyostelium discoideum 57287 R-DDI-162683 https://reactome.org/PathwayBrowser/#/R-DDI-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Dictyostelium discoideum 57287 R-DDI-1678660 https://reactome.org/PathwayBrowser/#/R-DDI-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Dictyostelium discoideum 57287 R-DDI-189442 https://reactome.org/PathwayBrowser/#/R-DDI-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Dictyostelium discoideum 57287 R-DDI-191323 https://reactome.org/PathwayBrowser/#/R-DDI-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Dictyostelium discoideum 57287 R-DDI-191352 https://reactome.org/PathwayBrowser/#/R-DDI-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Dictyostelium discoideum 57287 R-DDI-196773 https://reactome.org/PathwayBrowser/#/R-DDI-196773 COASY phosphorylates DP-CoA IEA Dictyostelium discoideum 57287 R-DDI-199202 https://reactome.org/PathwayBrowser/#/R-DDI-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Dictyostelium discoideum 57287 R-DDI-199216 https://reactome.org/PathwayBrowser/#/R-DDI-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Dictyostelium discoideum 57287 R-DDI-201035 https://reactome.org/PathwayBrowser/#/R-DDI-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Dictyostelium discoideum 57287 R-DDI-2046083 https://reactome.org/PathwayBrowser/#/R-DDI-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-2046085 https://reactome.org/PathwayBrowser/#/R-DDI-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-2046088 https://reactome.org/PathwayBrowser/#/R-DDI-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-2046090 https://reactome.org/PathwayBrowser/#/R-DDI-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-2046094 https://reactome.org/PathwayBrowser/#/R-DDI-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-2046095 https://reactome.org/PathwayBrowser/#/R-DDI-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-2046098 https://reactome.org/PathwayBrowser/#/R-DDI-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-2046100 https://reactome.org/PathwayBrowser/#/R-DDI-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-2066788 https://reactome.org/PathwayBrowser/#/R-DDI-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Dictyostelium discoideum 57287 R-DDI-2090085 https://reactome.org/PathwayBrowser/#/R-DDI-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Dictyostelium discoideum 57287 R-DDI-2465919 https://reactome.org/PathwayBrowser/#/R-DDI-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Dictyostelium discoideum 57287 R-DDI-2468039 https://reactome.org/PathwayBrowser/#/R-DDI-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Dictyostelium discoideum 57287 R-DDI-2473152 https://reactome.org/PathwayBrowser/#/R-DDI-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Dictyostelium discoideum 57287 R-DDI-2534087 https://reactome.org/PathwayBrowser/#/R-DDI-2534087 NMT1/2 transfer MYS to GNAT1 IEA Dictyostelium discoideum 57287 R-DDI-2545253 https://reactome.org/PathwayBrowser/#/R-DDI-2545253 Deacetylation of cohesin IEA Dictyostelium discoideum 57287 R-DDI-3318413 https://reactome.org/PathwayBrowser/#/R-DDI-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Dictyostelium discoideum 57287 R-DDI-3318486 https://reactome.org/PathwayBrowser/#/R-DDI-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Dictyostelium discoideum 57287 R-DDI-351207 https://reactome.org/PathwayBrowser/#/R-DDI-351207 Spermine => N-acetylated spermine IEA Dictyostelium discoideum 57287 R-DDI-351208 https://reactome.org/PathwayBrowser/#/R-DDI-351208 Spermidine => N-acetylated spermidine IEA Dictyostelium discoideum 57287 R-DDI-3662318 https://reactome.org/PathwayBrowser/#/R-DDI-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Dictyostelium discoideum 57287 R-DDI-390250 https://reactome.org/PathwayBrowser/#/R-DDI-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-390425 https://reactome.org/PathwayBrowser/#/R-DDI-390425 FAR1 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 57287 R-DDI-390438 https://reactome.org/PathwayBrowser/#/R-DDI-390438 FAR2 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 57287 R-DDI-428185 https://reactome.org/PathwayBrowser/#/R-DDI-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Dictyostelium discoideum 57287 R-DDI-449734 https://reactome.org/PathwayBrowser/#/R-DDI-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Dictyostelium discoideum 57287 R-DDI-449911 https://reactome.org/PathwayBrowser/#/R-DDI-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Dictyostelium discoideum 57287 R-DDI-548800 https://reactome.org/PathwayBrowser/#/R-DDI-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Dictyostelium discoideum 57287 R-DDI-548814 https://reactome.org/PathwayBrowser/#/R-DDI-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Dictyostelium discoideum 57287 R-DDI-549112 https://reactome.org/PathwayBrowser/#/R-DDI-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Dictyostelium discoideum 57287 R-DDI-549192 https://reactome.org/PathwayBrowser/#/R-DDI-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Dictyostelium discoideum 57287 R-DDI-5618331 https://reactome.org/PathwayBrowser/#/R-DDI-5618331 HDAC6 deacetylates microtubules IEA Dictyostelium discoideum 57287 R-DDI-5682044 https://reactome.org/PathwayBrowser/#/R-DDI-5682044 KAT5 acetylates ATM at DNA DSBs IEA Dictyostelium discoideum 57287 R-DDI-5690043 https://reactome.org/PathwayBrowser/#/R-DDI-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 57287 R-DDI-5690046 https://reactome.org/PathwayBrowser/#/R-DDI-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Dictyostelium discoideum 57287 R-DDI-5690066 https://reactome.org/PathwayBrowser/#/R-DDI-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 57287 R-DDI-5695957 https://reactome.org/PathwayBrowser/#/R-DDI-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Dictyostelium discoideum 57287 R-DDI-5696007 https://reactome.org/PathwayBrowser/#/R-DDI-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Dictyostelium discoideum 57287 R-DDI-5696424 https://reactome.org/PathwayBrowser/#/R-DDI-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Dictyostelium discoideum 57287 R-DDI-5696448 https://reactome.org/PathwayBrowser/#/R-DDI-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Dictyostelium discoideum 57287 R-DDI-6792712 https://reactome.org/PathwayBrowser/#/R-DDI-6792712 KAT5 acetylates ATM at shortened telomeres IEA Dictyostelium discoideum 57287 R-DDI-6800334 https://reactome.org/PathwayBrowser/#/R-DDI-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Dictyostelium discoideum 57287 R-DDI-70542 https://reactome.org/PathwayBrowser/#/R-DDI-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Dictyostelium discoideum 57287 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 57287 R-DDI-70844 https://reactome.org/PathwayBrowser/#/R-DDI-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-70881 https://reactome.org/PathwayBrowser/#/R-DDI-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Dictyostelium discoideum 57287 R-DDI-70893 https://reactome.org/PathwayBrowser/#/R-DDI-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 57287 R-DDI-70975 https://reactome.org/PathwayBrowser/#/R-DDI-70975 CS acetylates OA to citrate IEA Dictyostelium discoideum 57287 R-DDI-70997 https://reactome.org/PathwayBrowser/#/R-DDI-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-71037 https://reactome.org/PathwayBrowser/#/R-DDI-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 57287 R-DDI-71735 https://reactome.org/PathwayBrowser/#/R-DDI-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Dictyostelium discoideum 57287 R-DDI-71775 https://reactome.org/PathwayBrowser/#/R-DDI-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-73916 https://reactome.org/PathwayBrowser/#/R-DDI-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Dictyostelium discoideum 57287 R-DDI-73918 https://reactome.org/PathwayBrowser/#/R-DDI-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Dictyostelium discoideum 57287 R-DDI-74181 https://reactome.org/PathwayBrowser/#/R-DDI-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Dictyostelium discoideum 57287 R-DDI-75848 https://reactome.org/PathwayBrowser/#/R-DDI-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Dictyostelium discoideum 57287 R-DDI-75872 https://reactome.org/PathwayBrowser/#/R-DDI-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Dictyostelium discoideum 57287 R-DDI-75885 https://reactome.org/PathwayBrowser/#/R-DDI-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Dictyostelium discoideum 57287 R-DDI-75900 https://reactome.org/PathwayBrowser/#/R-DDI-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Dictyostelium discoideum 57287 R-DDI-8848215 https://reactome.org/PathwayBrowser/#/R-DDI-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Dictyostelium discoideum 57287 R-DDI-8848580 https://reactome.org/PathwayBrowser/#/R-DDI-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Dictyostelium discoideum 57287 R-DDI-8848582 https://reactome.org/PathwayBrowser/#/R-DDI-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Dictyostelium discoideum 57287 R-DDI-8848585 https://reactome.org/PathwayBrowser/#/R-DDI-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Dictyostelium discoideum 57287 R-DDI-8875071 https://reactome.org/PathwayBrowser/#/R-DDI-8875071 ACSS3 ligates CoA to CH3COO- IEA Dictyostelium discoideum 57287 R-DDI-8933547 https://reactome.org/PathwayBrowser/#/R-DDI-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Dictyostelium discoideum 57287 R-DDI-8954468 https://reactome.org/PathwayBrowser/#/R-DDI-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Dictyostelium discoideum 57287 R-DDI-9853512 https://reactome.org/PathwayBrowser/#/R-DDI-9853512 DLST transfers succinyl to CoA IEA Dictyostelium discoideum 57287 R-DDI-9861667 https://reactome.org/PathwayBrowser/#/R-DDI-9861667 DLAT trimer transfers acetyl to CoA IEA Dictyostelium discoideum 57287 R-DME-1482533 https://reactome.org/PathwayBrowser/#/R-DME-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Drosophila melanogaster 57287 R-DME-1482539 https://reactome.org/PathwayBrowser/#/R-DME-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Drosophila melanogaster 57287 R-DME-1482546 https://reactome.org/PathwayBrowser/#/R-DME-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Drosophila melanogaster 57287 R-DME-1482547 https://reactome.org/PathwayBrowser/#/R-DME-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Drosophila melanogaster 57287 R-DME-1482598 https://reactome.org/PathwayBrowser/#/R-DME-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Drosophila melanogaster 57287 R-DME-1482626 https://reactome.org/PathwayBrowser/#/R-DME-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Drosophila melanogaster 57287 R-DME-1482635 https://reactome.org/PathwayBrowser/#/R-DME-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Drosophila melanogaster 57287 R-DME-1482636 https://reactome.org/PathwayBrowser/#/R-DME-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Drosophila melanogaster 57287 R-DME-1482646 https://reactome.org/PathwayBrowser/#/R-DME-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Drosophila melanogaster 57287 R-DME-1482667 https://reactome.org/PathwayBrowser/#/R-DME-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Drosophila melanogaster 57287 R-DME-1482689 https://reactome.org/PathwayBrowser/#/R-DME-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Drosophila melanogaster 57287 R-DME-1482691 https://reactome.org/PathwayBrowser/#/R-DME-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Drosophila melanogaster 57287 R-DME-1482695 https://reactome.org/PathwayBrowser/#/R-DME-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Drosophila melanogaster 57287 R-DME-1482775 https://reactome.org/PathwayBrowser/#/R-DME-1482775 MLCL is acylated to CL by HADH (IM) IEA Drosophila melanogaster 57287 R-DME-1482889 https://reactome.org/PathwayBrowser/#/R-DME-1482889 DAG is acylated to TAG by DGAT1/2 IEA Drosophila melanogaster 57287 R-DME-1483002 https://reactome.org/PathwayBrowser/#/R-DME-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Drosophila melanogaster 57287 R-DME-159425 https://reactome.org/PathwayBrowser/#/R-DME-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 57287 R-DME-162683 https://reactome.org/PathwayBrowser/#/R-DME-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Drosophila melanogaster 57287 R-DME-1678660 https://reactome.org/PathwayBrowser/#/R-DME-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Drosophila melanogaster 57287 R-DME-189442 https://reactome.org/PathwayBrowser/#/R-DME-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Drosophila melanogaster 57287 R-DME-191323 https://reactome.org/PathwayBrowser/#/R-DME-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Drosophila melanogaster 57287 R-DME-191352 https://reactome.org/PathwayBrowser/#/R-DME-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Drosophila melanogaster 57287 R-DME-192137 https://reactome.org/PathwayBrowser/#/R-DME-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 57287 R-DME-192341 https://reactome.org/PathwayBrowser/#/R-DME-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Drosophila melanogaster 57287 R-DME-193401 https://reactome.org/PathwayBrowser/#/R-DME-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 57287 R-DME-193407 https://reactome.org/PathwayBrowser/#/R-DME-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 57287 R-DME-193424 https://reactome.org/PathwayBrowser/#/R-DME-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 57287 R-DME-193533 https://reactome.org/PathwayBrowser/#/R-DME-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Drosophila melanogaster 57287 R-DME-193711 https://reactome.org/PathwayBrowser/#/R-DME-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 57287 R-DME-193727 https://reactome.org/PathwayBrowser/#/R-DME-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 57287 R-DME-193743 https://reactome.org/PathwayBrowser/#/R-DME-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 57287 R-DME-193766 https://reactome.org/PathwayBrowser/#/R-DME-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 57287 R-DME-196857 https://reactome.org/PathwayBrowser/#/R-DME-196857 PANK2 phosphorylates PanK IEA Drosophila melanogaster 57287 R-DME-199202 https://reactome.org/PathwayBrowser/#/R-DME-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Drosophila melanogaster 57287 R-DME-200406 https://reactome.org/PathwayBrowser/#/R-DME-200406 CPT1A,B transfers PALM to CAR IEA Drosophila melanogaster 57287 R-DME-200410 https://reactome.org/PathwayBrowser/#/R-DME-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Drosophila melanogaster 57287 R-DME-201035 https://reactome.org/PathwayBrowser/#/R-DME-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Drosophila melanogaster 57287 R-DME-2046083 https://reactome.org/PathwayBrowser/#/R-DME-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Drosophila melanogaster 57287 R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster 57287 R-DME-2046090 https://reactome.org/PathwayBrowser/#/R-DME-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Drosophila melanogaster 57287 R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster 57287 R-DME-2046095 https://reactome.org/PathwayBrowser/#/R-DME-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Drosophila melanogaster 57287 R-DME-2046100 https://reactome.org/PathwayBrowser/#/R-DME-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Drosophila melanogaster 57287 R-DME-2066781 https://reactome.org/PathwayBrowser/#/R-DME-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Drosophila melanogaster 57287 R-DME-2090085 https://reactome.org/PathwayBrowser/#/R-DME-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Drosophila melanogaster 57287 R-DME-2465919 https://reactome.org/PathwayBrowser/#/R-DME-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Drosophila melanogaster 57287 R-DME-2468039 https://reactome.org/PathwayBrowser/#/R-DME-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Drosophila melanogaster 57287 R-DME-2473152 https://reactome.org/PathwayBrowser/#/R-DME-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Drosophila melanogaster 57287 R-DME-264622 https://reactome.org/PathwayBrowser/#/R-DME-264622 Cho is acetylated to AcCho by CHAT IEA Drosophila melanogaster 57287 R-DME-3318415 https://reactome.org/PathwayBrowser/#/R-DME-3318415 ATF2 acetylates histone H2B, H4 IEA Drosophila melanogaster 57287 R-DME-3321805 https://reactome.org/PathwayBrowser/#/R-DME-3321805 NSL acetylates histone H4 IEA Drosophila melanogaster 57287 R-DME-3321883 https://reactome.org/PathwayBrowser/#/R-DME-3321883 MSL acetylates histone H4 IEA Drosophila melanogaster 57287 R-DME-351207 https://reactome.org/PathwayBrowser/#/R-DME-351207 Spermine => N-acetylated spermine IEA Drosophila melanogaster 57287 R-DME-351208 https://reactome.org/PathwayBrowser/#/R-DME-351208 Spermidine => N-acetylated spermidine IEA Drosophila melanogaster 57287 R-DME-3662318 https://reactome.org/PathwayBrowser/#/R-DME-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Drosophila melanogaster 57287 R-DME-3662335 https://reactome.org/PathwayBrowser/#/R-DME-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Drosophila melanogaster 57287 R-DME-389622 https://reactome.org/PathwayBrowser/#/R-DME-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 57287 R-DME-389632 https://reactome.org/PathwayBrowser/#/R-DME-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 57287 R-DME-390224 https://reactome.org/PathwayBrowser/#/R-DME-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Drosophila melanogaster 57287 R-DME-390281 https://reactome.org/PathwayBrowser/#/R-DME-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Drosophila melanogaster 57287 R-DME-390284 https://reactome.org/PathwayBrowser/#/R-DME-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Drosophila melanogaster 57287 R-DME-390291 https://reactome.org/PathwayBrowser/#/R-DME-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Drosophila melanogaster 57287 R-DME-390425 https://reactome.org/PathwayBrowser/#/R-DME-390425 FAR1 reduces PalmCoA to HXOL IEA Drosophila melanogaster 57287 R-DME-390438 https://reactome.org/PathwayBrowser/#/R-DME-390438 FAR2 reduces PalmCoA to HXOL IEA Drosophila melanogaster 57287 R-DME-428127 https://reactome.org/PathwayBrowser/#/R-DME-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Drosophila melanogaster 57287 R-DME-428185 https://reactome.org/PathwayBrowser/#/R-DME-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Drosophila melanogaster 57287 R-DME-434382 https://reactome.org/PathwayBrowser/#/R-DME-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Drosophila melanogaster 57287 R-DME-449734 https://reactome.org/PathwayBrowser/#/R-DME-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Drosophila melanogaster 57287 R-DME-5358343 https://reactome.org/PathwayBrowser/#/R-DME-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Drosophila melanogaster 57287 R-DME-548800 https://reactome.org/PathwayBrowser/#/R-DME-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Drosophila melanogaster 57287 R-DME-548814 https://reactome.org/PathwayBrowser/#/R-DME-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Drosophila melanogaster 57287 R-DME-548815 https://reactome.org/PathwayBrowser/#/R-DME-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Drosophila melanogaster 57287 R-DME-548843 https://reactome.org/PathwayBrowser/#/R-DME-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Drosophila melanogaster 57287 R-DME-549112 https://reactome.org/PathwayBrowser/#/R-DME-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Drosophila melanogaster 57287 R-DME-549192 https://reactome.org/PathwayBrowser/#/R-DME-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Drosophila melanogaster 57287 R-DME-5628871 https://reactome.org/PathwayBrowser/#/R-DME-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Drosophila melanogaster 57287 R-DME-5660660 https://reactome.org/PathwayBrowser/#/R-DME-5660660 p300 acetylates RELA subunit IEA Drosophila melanogaster 57287 R-DME-5682044 https://reactome.org/PathwayBrowser/#/R-DME-5682044 KAT5 acetylates ATM at DNA DSBs IEA Drosophila melanogaster 57287 R-DME-5682084 https://reactome.org/PathwayBrowser/#/R-DME-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Drosophila melanogaster 57287 R-DME-5690043 https://reactome.org/PathwayBrowser/#/R-DME-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 57287 R-DME-5690046 https://reactome.org/PathwayBrowser/#/R-DME-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Drosophila melanogaster 57287 R-DME-5690066 https://reactome.org/PathwayBrowser/#/R-DME-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 57287 R-DME-5695957 https://reactome.org/PathwayBrowser/#/R-DME-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Drosophila melanogaster 57287 R-DME-5696004 https://reactome.org/PathwayBrowser/#/R-DME-5696004 ACSF2 ligates CoA-SH to MCFA IEA Drosophila melanogaster 57287 R-DME-5696007 https://reactome.org/PathwayBrowser/#/R-DME-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Drosophila melanogaster 57287 R-DME-5696424 https://reactome.org/PathwayBrowser/#/R-DME-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Drosophila melanogaster 57287 R-DME-5696448 https://reactome.org/PathwayBrowser/#/R-DME-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Drosophila melanogaster 57287 R-DME-6792712 https://reactome.org/PathwayBrowser/#/R-DME-6792712 KAT5 acetylates ATM at shortened telomeres IEA Drosophila melanogaster 57287 R-DME-6800334 https://reactome.org/PathwayBrowser/#/R-DME-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Drosophila melanogaster 57287 R-DME-6805638 https://reactome.org/PathwayBrowser/#/R-DME-6805638 KAT6A acetylates TP53 IEA Drosophila melanogaster 57287 R-DME-6811508 https://reactome.org/PathwayBrowser/#/R-DME-6811508 ING2-bound EP300 acetylates TP53 IEA Drosophila melanogaster 57287 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 57287 R-DME-70844 https://reactome.org/PathwayBrowser/#/R-DME-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Drosophila melanogaster 57287 R-DME-70881 https://reactome.org/PathwayBrowser/#/R-DME-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Drosophila melanogaster 57287 R-DME-70893 https://reactome.org/PathwayBrowser/#/R-DME-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 57287 R-DME-70975 https://reactome.org/PathwayBrowser/#/R-DME-70975 CS acetylates OA to citrate IEA Drosophila melanogaster 57287 R-DME-70997 https://reactome.org/PathwayBrowser/#/R-DME-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Drosophila melanogaster 57287 R-DME-71037 https://reactome.org/PathwayBrowser/#/R-DME-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 57287 R-DME-71735 https://reactome.org/PathwayBrowser/#/R-DME-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Drosophila melanogaster 57287 R-DME-71775 https://reactome.org/PathwayBrowser/#/R-DME-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Drosophila melanogaster 57287 R-DME-73916 https://reactome.org/PathwayBrowser/#/R-DME-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Drosophila melanogaster 57287 R-DME-73918 https://reactome.org/PathwayBrowser/#/R-DME-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Drosophila melanogaster 57287 R-DME-74181 https://reactome.org/PathwayBrowser/#/R-DME-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Drosophila melanogaster 57287 R-DME-75848 https://reactome.org/PathwayBrowser/#/R-DME-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Drosophila melanogaster 57287 R-DME-75872 https://reactome.org/PathwayBrowser/#/R-DME-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Drosophila melanogaster 57287 R-DME-75879 https://reactome.org/PathwayBrowser/#/R-DME-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Drosophila melanogaster 57287 R-DME-75885 https://reactome.org/PathwayBrowser/#/R-DME-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Drosophila melanogaster 57287 R-DME-75886 https://reactome.org/PathwayBrowser/#/R-DME-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Drosophila melanogaster 57287 R-DME-75900 https://reactome.org/PathwayBrowser/#/R-DME-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Drosophila melanogaster 57287 R-DME-77271 https://reactome.org/PathwayBrowser/#/R-DME-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Drosophila melanogaster 57287 R-DME-77304 https://reactome.org/PathwayBrowser/#/R-DME-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Drosophila melanogaster 57287 R-DME-77309 https://reactome.org/PathwayBrowser/#/R-DME-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Drosophila melanogaster 57287 R-DME-77321 https://reactome.org/PathwayBrowser/#/R-DME-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Drosophila melanogaster 57287 R-DME-77329 https://reactome.org/PathwayBrowser/#/R-DME-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Drosophila melanogaster 57287 R-DME-77340 https://reactome.org/PathwayBrowser/#/R-DME-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Drosophila melanogaster 57287 R-DME-8848215 https://reactome.org/PathwayBrowser/#/R-DME-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Drosophila melanogaster 57287 R-DME-8848580 https://reactome.org/PathwayBrowser/#/R-DME-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Drosophila melanogaster 57287 R-DME-8848582 https://reactome.org/PathwayBrowser/#/R-DME-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Drosophila melanogaster 57287 R-DME-8848585 https://reactome.org/PathwayBrowser/#/R-DME-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Drosophila melanogaster 57287 R-DME-8849345 https://reactome.org/PathwayBrowser/#/R-DME-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Drosophila melanogaster 57287 R-DME-8874745 https://reactome.org/PathwayBrowser/#/R-DME-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Drosophila melanogaster 57287 R-DME-8875071 https://reactome.org/PathwayBrowser/#/R-DME-8875071 ACSS3 ligates CoA to CH3COO- IEA Drosophila melanogaster 57287 R-DME-8876696 https://reactome.org/PathwayBrowser/#/R-DME-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Drosophila melanogaster 57287 R-DME-8933547 https://reactome.org/PathwayBrowser/#/R-DME-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Drosophila melanogaster 57287 R-DME-8951966 https://reactome.org/PathwayBrowser/#/R-DME-8951966 EP300 acetylates RUNX3 IEA Drosophila melanogaster 57287 R-DME-9021072 https://reactome.org/PathwayBrowser/#/R-DME-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Drosophila melanogaster 57287 R-DME-9620515 https://reactome.org/PathwayBrowser/#/R-DME-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Drosophila melanogaster 57287 R-DME-9647982 https://reactome.org/PathwayBrowser/#/R-DME-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Drosophila melanogaster 57287 R-DME-9701531 https://reactome.org/PathwayBrowser/#/R-DME-9701531 p-Y705,S727 STAT3 is acetylated IEA Drosophila melanogaster 57287 R-DME-9734535 https://reactome.org/PathwayBrowser/#/R-DME-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Drosophila melanogaster 57287 R-DME-9760081 https://reactome.org/PathwayBrowser/#/R-DME-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Drosophila melanogaster 57287 R-DME-9825747 https://reactome.org/PathwayBrowser/#/R-DME-9825747 CREBBP acetylates HINT1 dimer IEA Drosophila melanogaster 57287 R-DME-9837333 https://reactome.org/PathwayBrowser/#/R-DME-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Drosophila melanogaster 57287 R-DME-9837337 https://reactome.org/PathwayBrowser/#/R-DME-9837337 DCAKD phosphorylates DP-CoA IEA Drosophila melanogaster 57287 R-DME-9853512 https://reactome.org/PathwayBrowser/#/R-DME-9853512 DLST transfers succinyl to CoA IEA Drosophila melanogaster 57287 R-DME-9861667 https://reactome.org/PathwayBrowser/#/R-DME-9861667 DLAT trimer transfers acetyl to CoA IEA Drosophila melanogaster 57287 R-DRE-1482533 https://reactome.org/PathwayBrowser/#/R-DRE-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Danio rerio 57287 R-DRE-1482539 https://reactome.org/PathwayBrowser/#/R-DRE-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Danio rerio 57287 R-DRE-1482546 https://reactome.org/PathwayBrowser/#/R-DRE-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Danio rerio 57287 R-DRE-1482547 https://reactome.org/PathwayBrowser/#/R-DRE-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Danio rerio 57287 R-DRE-1482598 https://reactome.org/PathwayBrowser/#/R-DRE-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Danio rerio 57287 R-DRE-1482626 https://reactome.org/PathwayBrowser/#/R-DRE-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Danio rerio 57287 R-DRE-1482635 https://reactome.org/PathwayBrowser/#/R-DRE-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Danio rerio 57287 R-DRE-1482689 https://reactome.org/PathwayBrowser/#/R-DRE-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Danio rerio 57287 R-DRE-1482695 https://reactome.org/PathwayBrowser/#/R-DRE-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Danio rerio 57287 R-DRE-1482775 https://reactome.org/PathwayBrowser/#/R-DRE-1482775 MLCL is acylated to CL by HADH (IM) IEA Danio rerio 57287 R-DRE-1482861 https://reactome.org/PathwayBrowser/#/R-DRE-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Danio rerio 57287 R-DRE-1482867 https://reactome.org/PathwayBrowser/#/R-DRE-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Danio rerio 57287 R-DRE-1482889 https://reactome.org/PathwayBrowser/#/R-DRE-1482889 DAG is acylated to TAG by DGAT1/2 IEA Danio rerio 57287 R-DRE-158832 https://reactome.org/PathwayBrowser/#/R-DRE-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Danio rerio 57287 R-DRE-159425 https://reactome.org/PathwayBrowser/#/R-DRE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 57287 R-DRE-159443 https://reactome.org/PathwayBrowser/#/R-DRE-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Danio rerio 57287 R-DRE-159567 https://reactome.org/PathwayBrowser/#/R-DRE-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Danio rerio 57287 R-DRE-174959 https://reactome.org/PathwayBrowser/#/R-DRE-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Danio rerio 57287 R-DRE-177157 https://reactome.org/PathwayBrowser/#/R-DRE-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Danio rerio 57287 R-DRE-189442 https://reactome.org/PathwayBrowser/#/R-DRE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Danio rerio 57287 R-DRE-191352 https://reactome.org/PathwayBrowser/#/R-DRE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Danio rerio 57287 R-DRE-192137 https://reactome.org/PathwayBrowser/#/R-DRE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 57287 R-DRE-192341 https://reactome.org/PathwayBrowser/#/R-DRE-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Danio rerio 57287 R-DRE-193385 https://reactome.org/PathwayBrowser/#/R-DRE-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Danio rerio 57287 R-DRE-193407 https://reactome.org/PathwayBrowser/#/R-DRE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 57287 R-DRE-193533 https://reactome.org/PathwayBrowser/#/R-DRE-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Danio rerio 57287 R-DRE-193711 https://reactome.org/PathwayBrowser/#/R-DRE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 57287 R-DRE-193766 https://reactome.org/PathwayBrowser/#/R-DRE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 57287 R-DRE-196773 https://reactome.org/PathwayBrowser/#/R-DRE-196773 COASY phosphorylates DP-CoA IEA Danio rerio 57287 R-DRE-199216 https://reactome.org/PathwayBrowser/#/R-DRE-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Danio rerio 57287 R-DRE-200406 https://reactome.org/PathwayBrowser/#/R-DRE-200406 CPT1A,B transfers PALM to CAR IEA Danio rerio 57287 R-DRE-200410 https://reactome.org/PathwayBrowser/#/R-DRE-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Danio rerio 57287 R-DRE-201035 https://reactome.org/PathwayBrowser/#/R-DRE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Danio rerio 57287 R-DRE-2046083 https://reactome.org/PathwayBrowser/#/R-DRE-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Danio rerio 57287 R-DRE-2046085 https://reactome.org/PathwayBrowser/#/R-DRE-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Danio rerio 57287 R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio 57287 R-DRE-2046090 https://reactome.org/PathwayBrowser/#/R-DRE-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 57287 R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio 57287 R-DRE-2046095 https://reactome.org/PathwayBrowser/#/R-DRE-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Danio rerio 57287 R-DRE-2046098 https://reactome.org/PathwayBrowser/#/R-DRE-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Danio rerio 57287 R-DRE-2046100 https://reactome.org/PathwayBrowser/#/R-DRE-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Danio rerio 57287 R-DRE-2066779 https://reactome.org/PathwayBrowser/#/R-DRE-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Danio rerio 57287 R-DRE-2066781 https://reactome.org/PathwayBrowser/#/R-DRE-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Danio rerio 57287 R-DRE-2066788 https://reactome.org/PathwayBrowser/#/R-DRE-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Danio rerio 57287 R-DRE-209792 https://reactome.org/PathwayBrowser/#/R-DRE-209792 N-acetylation of serotonin IEA Danio rerio 57287 R-DRE-2465919 https://reactome.org/PathwayBrowser/#/R-DRE-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Danio rerio 57287 R-DRE-2468039 https://reactome.org/PathwayBrowser/#/R-DRE-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Danio rerio 57287 R-DRE-2473152 https://reactome.org/PathwayBrowser/#/R-DRE-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Danio rerio 57287 R-DRE-2534087 https://reactome.org/PathwayBrowser/#/R-DRE-2534087 NMT1/2 transfer MYS to GNAT1 IEA Danio rerio 57287 R-DRE-2545253 https://reactome.org/PathwayBrowser/#/R-DRE-2545253 Deacetylation of cohesin IEA Danio rerio 57287 R-DRE-264622 https://reactome.org/PathwayBrowser/#/R-DRE-264622 Cho is acetylated to AcCho by CHAT IEA Danio rerio 57287 R-DRE-351207 https://reactome.org/PathwayBrowser/#/R-DRE-351207 Spermine => N-acetylated spermine IEA Danio rerio 57287 R-DRE-351208 https://reactome.org/PathwayBrowser/#/R-DRE-351208 Spermidine => N-acetylated spermidine IEA Danio rerio 57287 R-DRE-3662318 https://reactome.org/PathwayBrowser/#/R-DRE-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Danio rerio 57287 R-DRE-390224 https://reactome.org/PathwayBrowser/#/R-DRE-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Danio rerio 57287 R-DRE-390250 https://reactome.org/PathwayBrowser/#/R-DRE-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Danio rerio 57287 R-DRE-390281 https://reactome.org/PathwayBrowser/#/R-DRE-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Danio rerio 57287 R-DRE-390284 https://reactome.org/PathwayBrowser/#/R-DRE-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Danio rerio 57287 R-DRE-390291 https://reactome.org/PathwayBrowser/#/R-DRE-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Danio rerio 57287 R-DRE-390304 https://reactome.org/PathwayBrowser/#/R-DRE-390304 acetyl-CoA + H2O => acetate + CoASH IEA Danio rerio 57287 R-DRE-390438 https://reactome.org/PathwayBrowser/#/R-DRE-390438 FAR2 reduces PalmCoA to HXOL IEA Danio rerio 57287 R-DRE-428127 https://reactome.org/PathwayBrowser/#/R-DRE-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Danio rerio 57287 R-DRE-428185 https://reactome.org/PathwayBrowser/#/R-DRE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Danio rerio 57287 R-DRE-434382 https://reactome.org/PathwayBrowser/#/R-DRE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Danio rerio 57287 R-DRE-449734 https://reactome.org/PathwayBrowser/#/R-DRE-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Danio rerio 57287 R-DRE-548800 https://reactome.org/PathwayBrowser/#/R-DRE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Danio rerio 57287 R-DRE-548814 https://reactome.org/PathwayBrowser/#/R-DRE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Danio rerio 57287 R-DRE-548815 https://reactome.org/PathwayBrowser/#/R-DRE-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Danio rerio 57287 R-DRE-548843 https://reactome.org/PathwayBrowser/#/R-DRE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Danio rerio 57287 R-DRE-549112 https://reactome.org/PathwayBrowser/#/R-DRE-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Danio rerio 57287 R-DRE-549192 https://reactome.org/PathwayBrowser/#/R-DRE-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Danio rerio 57287 R-DRE-5682084 https://reactome.org/PathwayBrowser/#/R-DRE-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Danio rerio 57287 R-DRE-5686304 https://reactome.org/PathwayBrowser/#/R-DRE-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Danio rerio 57287 R-DRE-5690042 https://reactome.org/PathwayBrowser/#/R-DRE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 57287 R-DRE-5690046 https://reactome.org/PathwayBrowser/#/R-DRE-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Danio rerio 57287 R-DRE-5690066 https://reactome.org/PathwayBrowser/#/R-DRE-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 57287 R-DRE-5694494 https://reactome.org/PathwayBrowser/#/R-DRE-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Danio rerio 57287 R-DRE-5696004 https://reactome.org/PathwayBrowser/#/R-DRE-5696004 ACSF2 ligates CoA-SH to MCFA IEA Danio rerio 57287 R-DRE-5696424 https://reactome.org/PathwayBrowser/#/R-DRE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Danio rerio 57287 R-DRE-5696448 https://reactome.org/PathwayBrowser/#/R-DRE-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Danio rerio 57287 R-DRE-6800334 https://reactome.org/PathwayBrowser/#/R-DRE-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Danio rerio 57287 R-DRE-6805638 https://reactome.org/PathwayBrowser/#/R-DRE-6805638 KAT6A acetylates TP53 IEA Danio rerio 57287 R-DRE-70542 https://reactome.org/PathwayBrowser/#/R-DRE-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Danio rerio 57287 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 57287 R-DRE-70844 https://reactome.org/PathwayBrowser/#/R-DRE-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Danio rerio 57287 R-DRE-70881 https://reactome.org/PathwayBrowser/#/R-DRE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Danio rerio 57287 R-DRE-70893 https://reactome.org/PathwayBrowser/#/R-DRE-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Danio rerio 57287 R-DRE-70975 https://reactome.org/PathwayBrowser/#/R-DRE-70975 CS acetylates OA to citrate IEA Danio rerio 57287 R-DRE-70997 https://reactome.org/PathwayBrowser/#/R-DRE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Danio rerio 57287 R-DRE-71037 https://reactome.org/PathwayBrowser/#/R-DRE-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Danio rerio 57287 R-DRE-73916 https://reactome.org/PathwayBrowser/#/R-DRE-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Danio rerio 57287 R-DRE-74181 https://reactome.org/PathwayBrowser/#/R-DRE-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Danio rerio 57287 R-DRE-75848 https://reactome.org/PathwayBrowser/#/R-DRE-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Danio rerio 57287 R-DRE-75872 https://reactome.org/PathwayBrowser/#/R-DRE-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Danio rerio 57287 R-DRE-75885 https://reactome.org/PathwayBrowser/#/R-DRE-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Danio rerio 57287 R-DRE-75900 https://reactome.org/PathwayBrowser/#/R-DRE-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Danio rerio 57287 R-DRE-77271 https://reactome.org/PathwayBrowser/#/R-DRE-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Danio rerio 57287 R-DRE-77304 https://reactome.org/PathwayBrowser/#/R-DRE-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Danio rerio 57287 R-DRE-77309 https://reactome.org/PathwayBrowser/#/R-DRE-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Danio rerio 57287 R-DRE-77321 https://reactome.org/PathwayBrowser/#/R-DRE-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Danio rerio 57287 R-DRE-77329 https://reactome.org/PathwayBrowser/#/R-DRE-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Danio rerio 57287 R-DRE-77340 https://reactome.org/PathwayBrowser/#/R-DRE-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Danio rerio 57287 R-DRE-8848215 https://reactome.org/PathwayBrowser/#/R-DRE-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Danio rerio 57287 R-DRE-8848580 https://reactome.org/PathwayBrowser/#/R-DRE-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Danio rerio 57287 R-DRE-8848582 https://reactome.org/PathwayBrowser/#/R-DRE-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Danio rerio 57287 R-DRE-8848585 https://reactome.org/PathwayBrowser/#/R-DRE-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Danio rerio 57287 R-DRE-8849345 https://reactome.org/PathwayBrowser/#/R-DRE-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Danio rerio 57287 R-DRE-8874745 https://reactome.org/PathwayBrowser/#/R-DRE-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Danio rerio 57287 R-DRE-8876696 https://reactome.org/PathwayBrowser/#/R-DRE-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Danio rerio 57287 R-DRE-8954468 https://reactome.org/PathwayBrowser/#/R-DRE-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Danio rerio 57287 R-DRE-9021072 https://reactome.org/PathwayBrowser/#/R-DRE-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Danio rerio 57287 R-DRE-9620515 https://reactome.org/PathwayBrowser/#/R-DRE-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Danio rerio 57287 R-DRE-9749971 https://reactome.org/PathwayBrowser/#/R-DRE-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Danio rerio 57287 R-DRE-9753676 https://reactome.org/PathwayBrowser/#/R-DRE-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Danio rerio 57287 R-DRE-9837333 https://reactome.org/PathwayBrowser/#/R-DRE-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Danio rerio 57287 R-DRE-9837337 https://reactome.org/PathwayBrowser/#/R-DRE-9837337 DCAKD phosphorylates DP-CoA IEA Danio rerio 57287 R-DRE-9853512 https://reactome.org/PathwayBrowser/#/R-DRE-9853512 DLST transfers succinyl to CoA IEA Danio rerio 57287 R-DRE-9854415 https://reactome.org/PathwayBrowser/#/R-DRE-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Danio rerio 57287 R-GGA-1482533 https://reactome.org/PathwayBrowser/#/R-GGA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus 57287 R-GGA-1482539 https://reactome.org/PathwayBrowser/#/R-GGA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Gallus gallus 57287 R-GGA-1482546 https://reactome.org/PathwayBrowser/#/R-GGA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Gallus gallus 57287 R-GGA-1482547 https://reactome.org/PathwayBrowser/#/R-GGA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus 57287 R-GGA-1482548 https://reactome.org/PathwayBrowser/#/R-GGA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Gallus gallus 57287 R-GGA-1482635 https://reactome.org/PathwayBrowser/#/R-GGA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Gallus gallus 57287 R-GGA-1482636 https://reactome.org/PathwayBrowser/#/R-GGA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus 57287 R-GGA-1482646 https://reactome.org/PathwayBrowser/#/R-GGA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Gallus gallus 57287 R-GGA-1482667 https://reactome.org/PathwayBrowser/#/R-GGA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Gallus gallus 57287 R-GGA-1482689 https://reactome.org/PathwayBrowser/#/R-GGA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Gallus gallus 57287 R-GGA-1482691 https://reactome.org/PathwayBrowser/#/R-GGA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus 57287 R-GGA-1482695 https://reactome.org/PathwayBrowser/#/R-GGA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Gallus gallus 57287 R-GGA-1482775 https://reactome.org/PathwayBrowser/#/R-GGA-1482775 MLCL is acylated to CL by HADH (IM) IEA Gallus gallus 57287 R-GGA-1482861 https://reactome.org/PathwayBrowser/#/R-GGA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Gallus gallus 57287 R-GGA-1482867 https://reactome.org/PathwayBrowser/#/R-GGA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Gallus gallus 57287 R-GGA-1482889 https://reactome.org/PathwayBrowser/#/R-GGA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Gallus gallus 57287 R-GGA-158832 https://reactome.org/PathwayBrowser/#/R-GGA-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Gallus gallus 57287 R-GGA-159425 https://reactome.org/PathwayBrowser/#/R-GGA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 57287 R-GGA-159431 https://reactome.org/PathwayBrowser/#/R-GGA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Gallus gallus 57287 R-GGA-159443 https://reactome.org/PathwayBrowser/#/R-GGA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 57287 R-GGA-159566 https://reactome.org/PathwayBrowser/#/R-GGA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Gallus gallus 57287 R-GGA-159567 https://reactome.org/PathwayBrowser/#/R-GGA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Gallus gallus 57287 R-GGA-159574 https://reactome.org/PathwayBrowser/#/R-GGA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Gallus gallus 57287 R-GGA-162683 https://reactome.org/PathwayBrowser/#/R-GGA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Gallus gallus 57287 R-GGA-1678660 https://reactome.org/PathwayBrowser/#/R-GGA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Gallus gallus 57287 R-GGA-174959 https://reactome.org/PathwayBrowser/#/R-GGA-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Gallus gallus 57287 R-GGA-177157 https://reactome.org/PathwayBrowser/#/R-GGA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Gallus gallus 57287 R-GGA-189442 https://reactome.org/PathwayBrowser/#/R-GGA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Gallus gallus 57287 R-GGA-191323 https://reactome.org/PathwayBrowser/#/R-GGA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Gallus gallus 57287 R-GGA-191352 https://reactome.org/PathwayBrowser/#/R-GGA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Gallus gallus 57287 R-GGA-192137 https://reactome.org/PathwayBrowser/#/R-GGA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 57287 R-GGA-192312 https://reactome.org/PathwayBrowser/#/R-GGA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Gallus gallus 57287 R-GGA-192341 https://reactome.org/PathwayBrowser/#/R-GGA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Gallus gallus 57287 R-GGA-193385 https://reactome.org/PathwayBrowser/#/R-GGA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Gallus gallus 57287 R-GGA-193401 https://reactome.org/PathwayBrowser/#/R-GGA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 57287 R-GGA-193407 https://reactome.org/PathwayBrowser/#/R-GGA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 57287 R-GGA-193424 https://reactome.org/PathwayBrowser/#/R-GGA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 57287 R-GGA-193491 https://reactome.org/PathwayBrowser/#/R-GGA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Gallus gallus 57287 R-GGA-193533 https://reactome.org/PathwayBrowser/#/R-GGA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Gallus gallus 57287 R-GGA-193711 https://reactome.org/PathwayBrowser/#/R-GGA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 57287 R-GGA-193727 https://reactome.org/PathwayBrowser/#/R-GGA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 57287 R-GGA-193743 https://reactome.org/PathwayBrowser/#/R-GGA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 57287 R-GGA-193766 https://reactome.org/PathwayBrowser/#/R-GGA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 57287 R-GGA-196773 https://reactome.org/PathwayBrowser/#/R-GGA-196773 COASY phosphorylates DP-CoA IEA Gallus gallus 57287 R-GGA-196857 https://reactome.org/PathwayBrowser/#/R-GGA-196857 PANK2 phosphorylates PanK IEA Gallus gallus 57287 R-GGA-199202 https://reactome.org/PathwayBrowser/#/R-GGA-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Gallus gallus 57287 R-GGA-199216 https://reactome.org/PathwayBrowser/#/R-GGA-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Gallus gallus 57287 R-GGA-200406 https://reactome.org/PathwayBrowser/#/R-GGA-200406 CPT1A,B transfers PALM to CAR IEA Gallus gallus 57287 R-GGA-200410 https://reactome.org/PathwayBrowser/#/R-GGA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Gallus gallus 57287 R-GGA-201035 https://reactome.org/PathwayBrowser/#/R-GGA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Gallus gallus 57287 R-GGA-2046083 https://reactome.org/PathwayBrowser/#/R-GGA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Gallus gallus 57287 R-GGA-2046085 https://reactome.org/PathwayBrowser/#/R-GGA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Gallus gallus 57287 R-GGA-2046088 https://reactome.org/PathwayBrowser/#/R-GGA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Gallus gallus 57287 R-GGA-2046090 https://reactome.org/PathwayBrowser/#/R-GGA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 57287 R-GGA-2046094 https://reactome.org/PathwayBrowser/#/R-GGA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Gallus gallus 57287 R-GGA-2046095 https://reactome.org/PathwayBrowser/#/R-GGA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Gallus gallus 57287 R-GGA-2046098 https://reactome.org/PathwayBrowser/#/R-GGA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Gallus gallus 57287 R-GGA-2046100 https://reactome.org/PathwayBrowser/#/R-GGA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Gallus gallus 57287 R-GGA-2066779 https://reactome.org/PathwayBrowser/#/R-GGA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Gallus gallus 57287 R-GGA-2066781 https://reactome.org/PathwayBrowser/#/R-GGA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Gallus gallus 57287 R-GGA-2066788 https://reactome.org/PathwayBrowser/#/R-GGA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Gallus gallus 57287 R-GGA-2090085 https://reactome.org/PathwayBrowser/#/R-GGA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Gallus gallus 57287 R-GGA-209792 https://reactome.org/PathwayBrowser/#/R-GGA-209792 N-acetylation of serotonin IEA Gallus gallus 57287 R-GGA-2465919 https://reactome.org/PathwayBrowser/#/R-GGA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Gallus gallus 57287 R-GGA-2468039 https://reactome.org/PathwayBrowser/#/R-GGA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus 57287 R-GGA-2473152 https://reactome.org/PathwayBrowser/#/R-GGA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus 57287 R-GGA-2545203 https://reactome.org/PathwayBrowser/#/R-GGA-2545203 Deacetylation of cleaved cohesin IEA Gallus gallus 57287 R-GGA-2545253 https://reactome.org/PathwayBrowser/#/R-GGA-2545253 Deacetylation of cohesin IEA Gallus gallus 57287 R-GGA-264622 https://reactome.org/PathwayBrowser/#/R-GGA-264622 Cho is acetylated to AcCho by CHAT IEA Gallus gallus 57287 R-GGA-3318415 https://reactome.org/PathwayBrowser/#/R-GGA-3318415 ATF2 acetylates histone H2B, H4 IEA Gallus gallus 57287 R-GGA-3321883 https://reactome.org/PathwayBrowser/#/R-GGA-3321883 MSL acetylates histone H4 IEA Gallus gallus 57287 R-GGA-3371554 https://reactome.org/PathwayBrowser/#/R-GGA-3371554 HSF1 acetylation at Lys80 IEA Gallus gallus 57287 R-GGA-351207 https://reactome.org/PathwayBrowser/#/R-GGA-351207 Spermine => N-acetylated spermine IEA Gallus gallus 57287 R-GGA-351208 https://reactome.org/PathwayBrowser/#/R-GGA-351208 Spermidine => N-acetylated spermidine IEA Gallus gallus 57287 R-GGA-3662318 https://reactome.org/PathwayBrowser/#/R-GGA-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Gallus gallus 57287 R-GGA-3662335 https://reactome.org/PathwayBrowser/#/R-GGA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Gallus gallus 57287 R-GGA-372977 https://reactome.org/PathwayBrowser/#/R-GGA-372977 succinylCoA + ADP + Pi <=> succinate + CoASH + ATP TAS Gallus gallus 57287 R-GGA-372980 https://reactome.org/PathwayBrowser/#/R-GGA-372980 succinylCoA + GDP + Pi <=> succinate + CoASH + GTP TAS Gallus gallus 57287 R-GGA-373006 https://reactome.org/PathwayBrowser/#/R-GGA-373006 acetyl-CoA + H2O + oxaloacetate => citrate + CoA TAS Gallus gallus 57287 R-GGA-373042 https://reactome.org/PathwayBrowser/#/R-GGA-373042 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ IEA Gallus gallus 57287 R-GGA-373134 https://reactome.org/PathwayBrowser/#/R-GGA-373134 succinate + CoASH + ATP <=> succinylCoA + ADP + Pi TAS Gallus gallus 57287 R-GGA-373148 https://reactome.org/PathwayBrowser/#/R-GGA-373148 succinate + CoASH + GTP <=> succinylCoA + GDP + Pi TAS Gallus gallus 57287 R-GGA-373177 https://reactome.org/PathwayBrowser/#/R-GGA-373177 pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ TAS Gallus gallus 57287 R-GGA-389622 https://reactome.org/PathwayBrowser/#/R-GGA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 57287 R-GGA-389632 https://reactome.org/PathwayBrowser/#/R-GGA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 57287 R-GGA-390224 https://reactome.org/PathwayBrowser/#/R-GGA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Gallus gallus 57287 R-GGA-390250 https://reactome.org/PathwayBrowser/#/R-GGA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Gallus gallus 57287 R-GGA-390281 https://reactome.org/PathwayBrowser/#/R-GGA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Gallus gallus 57287 R-GGA-390284 https://reactome.org/PathwayBrowser/#/R-GGA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Gallus gallus 57287 R-GGA-390291 https://reactome.org/PathwayBrowser/#/R-GGA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Gallus gallus 57287 R-GGA-390304 https://reactome.org/PathwayBrowser/#/R-GGA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Gallus gallus 57287 R-GGA-390425 https://reactome.org/PathwayBrowser/#/R-GGA-390425 FAR1 reduces PalmCoA to HXOL IEA Gallus gallus 57287 R-GGA-390438 https://reactome.org/PathwayBrowser/#/R-GGA-390438 FAR2 reduces PalmCoA to HXOL IEA Gallus gallus 57287 R-GGA-421493 https://reactome.org/PathwayBrowser/#/R-GGA-421493 succinyl-CoA + glycine => delta-aminolevulinate + CoA SH + CO2 TAS Gallus gallus 57287 R-GGA-428127 https://reactome.org/PathwayBrowser/#/R-GGA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Gallus gallus 57287 R-GGA-428185 https://reactome.org/PathwayBrowser/#/R-GGA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Gallus gallus 57287 R-GGA-433550 https://reactome.org/PathwayBrowser/#/R-GGA-433550 palmitoyl-CoA + serine => 3-dehydrosphinganine + CoASH + CO2 IEA Gallus gallus 57287 R-GGA-433592 https://reactome.org/PathwayBrowser/#/R-GGA-433592 sphinganine + stearyl-CoA => dihydroceramide + CoASH IEA Gallus gallus 57287 R-GGA-434382 https://reactome.org/PathwayBrowser/#/R-GGA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Gallus gallus 57287 R-GGA-449734 https://reactome.org/PathwayBrowser/#/R-GGA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Gallus gallus 57287 R-GGA-449911 https://reactome.org/PathwayBrowser/#/R-GGA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Gallus gallus 57287 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus 57287 R-GGA-5358343 https://reactome.org/PathwayBrowser/#/R-GGA-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Gallus gallus 57287 R-GGA-548800 https://reactome.org/PathwayBrowser/#/R-GGA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Gallus gallus 57287 R-GGA-548814 https://reactome.org/PathwayBrowser/#/R-GGA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Gallus gallus 57287 R-GGA-548815 https://reactome.org/PathwayBrowser/#/R-GGA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Gallus gallus 57287 R-GGA-548843 https://reactome.org/PathwayBrowser/#/R-GGA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Gallus gallus 57287 R-GGA-549112 https://reactome.org/PathwayBrowser/#/R-GGA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Gallus gallus 57287 R-GGA-549192 https://reactome.org/PathwayBrowser/#/R-GGA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Gallus gallus 57287 R-GGA-5660660 https://reactome.org/PathwayBrowser/#/R-GGA-5660660 p300 acetylates RELA subunit IEA Gallus gallus 57287 R-GGA-5682044 https://reactome.org/PathwayBrowser/#/R-GGA-5682044 KAT5 acetylates ATM at DNA DSBs IEA Gallus gallus 57287 R-GGA-5682084 https://reactome.org/PathwayBrowser/#/R-GGA-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Gallus gallus 57287 R-GGA-5686304 https://reactome.org/PathwayBrowser/#/R-GGA-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Gallus gallus 57287 R-GGA-5690042 https://reactome.org/PathwayBrowser/#/R-GGA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 57287 R-GGA-5690043 https://reactome.org/PathwayBrowser/#/R-GGA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 57287 R-GGA-5690066 https://reactome.org/PathwayBrowser/#/R-GGA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 57287 R-GGA-5694494 https://reactome.org/PathwayBrowser/#/R-GGA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Gallus gallus 57287 R-GGA-5695957 https://reactome.org/PathwayBrowser/#/R-GGA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Gallus gallus 57287 R-GGA-5696004 https://reactome.org/PathwayBrowser/#/R-GGA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Gallus gallus 57287 R-GGA-5696424 https://reactome.org/PathwayBrowser/#/R-GGA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Gallus gallus 57287 R-GGA-5696448 https://reactome.org/PathwayBrowser/#/R-GGA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Gallus gallus 57287 R-GGA-6792712 https://reactome.org/PathwayBrowser/#/R-GGA-6792712 KAT5 acetylates ATM at shortened telomeres IEA Gallus gallus 57287 R-GGA-6800334 https://reactome.org/PathwayBrowser/#/R-GGA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Gallus gallus 57287 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 57287 R-GGA-70844 https://reactome.org/PathwayBrowser/#/R-GGA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Gallus gallus 57287 R-GGA-70881 https://reactome.org/PathwayBrowser/#/R-GGA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Gallus gallus 57287 R-GGA-70893 https://reactome.org/PathwayBrowser/#/R-GGA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Gallus gallus 57287 R-GGA-70975 https://reactome.org/PathwayBrowser/#/R-GGA-70975 CS acetylates OA to citrate IEA Gallus gallus 57287 R-GGA-70997 https://reactome.org/PathwayBrowser/#/R-GGA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Gallus gallus 57287 R-GGA-71037 https://reactome.org/PathwayBrowser/#/R-GGA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Gallus gallus 57287 R-GGA-71735 https://reactome.org/PathwayBrowser/#/R-GGA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Gallus gallus 57287 R-GGA-71775 https://reactome.org/PathwayBrowser/#/R-GGA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Gallus gallus 57287 R-GGA-73916 https://reactome.org/PathwayBrowser/#/R-GGA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Gallus gallus 57287 R-GGA-73918 https://reactome.org/PathwayBrowser/#/R-GGA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Gallus gallus 57287 R-GGA-74181 https://reactome.org/PathwayBrowser/#/R-GGA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Gallus gallus 57287 R-GGA-75848 https://reactome.org/PathwayBrowser/#/R-GGA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Gallus gallus 57287 R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Gallus gallus 57287 R-GGA-75885 https://reactome.org/PathwayBrowser/#/R-GGA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Gallus gallus 57287 R-GGA-75886 https://reactome.org/PathwayBrowser/#/R-GGA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Gallus gallus 57287 R-GGA-77271 https://reactome.org/PathwayBrowser/#/R-GGA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Gallus gallus 57287 R-GGA-77304 https://reactome.org/PathwayBrowser/#/R-GGA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Gallus gallus 57287 R-GGA-77309 https://reactome.org/PathwayBrowser/#/R-GGA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Gallus gallus 57287 R-GGA-77321 https://reactome.org/PathwayBrowser/#/R-GGA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Gallus gallus 57287 R-GGA-77329 https://reactome.org/PathwayBrowser/#/R-GGA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Gallus gallus 57287 R-GGA-77340 https://reactome.org/PathwayBrowser/#/R-GGA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Gallus gallus 57287 R-GGA-8848215 https://reactome.org/PathwayBrowser/#/R-GGA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Gallus gallus 57287 R-GGA-8848580 https://reactome.org/PathwayBrowser/#/R-GGA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Gallus gallus 57287 R-GGA-8848582 https://reactome.org/PathwayBrowser/#/R-GGA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Gallus gallus 57287 R-GGA-8848585 https://reactome.org/PathwayBrowser/#/R-GGA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Gallus gallus 57287 R-GGA-8849345 https://reactome.org/PathwayBrowser/#/R-GGA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Gallus gallus 57287 R-GGA-8874745 https://reactome.org/PathwayBrowser/#/R-GGA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Gallus gallus 57287 R-GGA-8875071 https://reactome.org/PathwayBrowser/#/R-GGA-8875071 ACSS3 ligates CoA to CH3COO- IEA Gallus gallus 57287 R-GGA-8876696 https://reactome.org/PathwayBrowser/#/R-GGA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Gallus gallus 57287 R-GGA-8933547 https://reactome.org/PathwayBrowser/#/R-GGA-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Gallus gallus 57287 R-GGA-8951966 https://reactome.org/PathwayBrowser/#/R-GGA-8951966 EP300 acetylates RUNX3 IEA Gallus gallus 57287 R-GGA-8954468 https://reactome.org/PathwayBrowser/#/R-GGA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Gallus gallus 57287 R-GGA-9021072 https://reactome.org/PathwayBrowser/#/R-GGA-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Gallus gallus 57287 R-GGA-9620515 https://reactome.org/PathwayBrowser/#/R-GGA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Gallus gallus 57287 R-GGA-9647982 https://reactome.org/PathwayBrowser/#/R-GGA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Gallus gallus 57287 R-GGA-9701531 https://reactome.org/PathwayBrowser/#/R-GGA-9701531 p-Y705,S727 STAT3 is acetylated IEA Gallus gallus 57287 R-GGA-9734535 https://reactome.org/PathwayBrowser/#/R-GGA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Gallus gallus 57287 R-GGA-9749971 https://reactome.org/PathwayBrowser/#/R-GGA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Gallus gallus 57287 R-GGA-9750001 https://reactome.org/PathwayBrowser/#/R-GGA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Gallus gallus 57287 R-GGA-9753676 https://reactome.org/PathwayBrowser/#/R-GGA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Gallus gallus 57287 R-GGA-9760081 https://reactome.org/PathwayBrowser/#/R-GGA-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Gallus gallus 57287 R-GGA-9825747 https://reactome.org/PathwayBrowser/#/R-GGA-9825747 CREBBP acetylates HINT1 dimer IEA Gallus gallus 57287 R-GGA-9837333 https://reactome.org/PathwayBrowser/#/R-GGA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Gallus gallus 57287 R-GGA-9837337 https://reactome.org/PathwayBrowser/#/R-GGA-9837337 DCAKD phosphorylates DP-CoA IEA Gallus gallus 57287 R-GGA-9853512 https://reactome.org/PathwayBrowser/#/R-GGA-9853512 DLST transfers succinyl to CoA IEA Gallus gallus 57287 R-GGA-9854415 https://reactome.org/PathwayBrowser/#/R-GGA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Gallus gallus 57287 R-GGA-9861667 https://reactome.org/PathwayBrowser/#/R-GGA-9861667 DLAT trimer transfers acetyl to CoA IEA Gallus gallus 57287 R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 57287 R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 57287 R-HSA-1482533 https://reactome.org/PathwayBrowser/#/R-HSA-1482533 2-acyl LPC is acylated to PC by LPCAT TAS Homo sapiens 57287 R-HSA-1482539 https://reactome.org/PathwayBrowser/#/R-HSA-1482539 1-acyl LPG is acylated to PG by LPGAT TAS Homo sapiens 57287 R-HSA-1482546 https://reactome.org/PathwayBrowser/#/R-HSA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) TAS Homo sapiens 57287 R-HSA-1482547 https://reactome.org/PathwayBrowser/#/R-HSA-1482547 1-acyl LPC is acylated to PC by LPCAT TAS Homo sapiens 57287 R-HSA-1482548 https://reactome.org/PathwayBrowser/#/R-HSA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) TAS Homo sapiens 57287 R-HSA-1482598 https://reactome.org/PathwayBrowser/#/R-HSA-1482598 1-acyl LPI is acylated to PI by MBOAT7 TAS Homo sapiens 57287 R-HSA-1482626 https://reactome.org/PathwayBrowser/#/R-HSA-1482626 2-acyl LPI is acylated to PI by MBOAT7 TAS Homo sapiens 57287 R-HSA-1482635 https://reactome.org/PathwayBrowser/#/R-HSA-1482635 2-acyl LPG is acylated to PG by LPGAT TAS Homo sapiens 57287 R-HSA-1482636 https://reactome.org/PathwayBrowser/#/R-HSA-1482636 1-acyl LPS is acylated to PS by LPSAT TAS Homo sapiens 57287 R-HSA-1482646 https://reactome.org/PathwayBrowser/#/R-HSA-1482646 2-acyl LPE is acylated to PE by LPEAT TAS Homo sapiens 57287 R-HSA-1482667 https://reactome.org/PathwayBrowser/#/R-HSA-1482667 1-acyl LPE is acylated to PE by LPEAT TAS Homo sapiens 57287 R-HSA-1482689 https://reactome.org/PathwayBrowser/#/R-HSA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) TAS Homo sapiens 57287 R-HSA-1482691 https://reactome.org/PathwayBrowser/#/R-HSA-1482691 2-acyl LPS is acylated to PS by LPSAT TAS Homo sapiens 57287 R-HSA-1482695 https://reactome.org/PathwayBrowser/#/R-HSA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) TAS Homo sapiens 57287 R-HSA-1482775 https://reactome.org/PathwayBrowser/#/R-HSA-1482775 MLCL is acylated to CL by HADH (IM) TAS Homo sapiens 57287 R-HSA-1482861 https://reactome.org/PathwayBrowser/#/R-HSA-1482861 MLCL is acylated to CL by LCLAT1 (ER) TAS Homo sapiens 57287 R-HSA-1482867 https://reactome.org/PathwayBrowser/#/R-HSA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) TAS Homo sapiens 57287 R-HSA-1482889 https://reactome.org/PathwayBrowser/#/R-HSA-1482889 DAG is acylated to TAG by DGAT1/2 TAS Homo sapiens 57287 R-HSA-1483002 https://reactome.org/PathwayBrowser/#/R-HSA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT TAS Homo sapiens 57287 R-HSA-158832 https://reactome.org/PathwayBrowser/#/R-HSA-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 TAS Homo sapiens 57287 R-HSA-159425 https://reactome.org/PathwayBrowser/#/R-HSA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 57287 R-HSA-159431 https://reactome.org/PathwayBrowser/#/R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine TAS Homo sapiens 57287 R-HSA-159443 https://reactome.org/PathwayBrowser/#/R-HSA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 57287 R-HSA-159566 https://reactome.org/PathwayBrowser/#/R-HSA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A TAS Homo sapiens 57287 R-HSA-159567 https://reactome.org/PathwayBrowser/#/R-HSA-159567 ACSM2B-like proteins transform ST to ST-CoA TAS Homo sapiens 57287 R-HSA-159574 https://reactome.org/PathwayBrowser/#/R-HSA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA TAS Homo sapiens 57287 R-HSA-162683 https://reactome.org/PathwayBrowser/#/R-HSA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH TAS Homo sapiens 57287 R-HSA-162914 https://reactome.org/PathwayBrowser/#/R-HSA-162914 Myristoylation of Nef TAS Homo sapiens 57287 R-HSA-1678660 https://reactome.org/PathwayBrowser/#/R-HSA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) TAS Homo sapiens 57287 R-HSA-174959 https://reactome.org/PathwayBrowser/#/R-HSA-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 TAS Homo sapiens 57287 R-HSA-177157 https://reactome.org/PathwayBrowser/#/R-HSA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate TAS Homo sapiens 57287 R-HSA-177160 https://reactome.org/PathwayBrowser/#/R-HSA-177160 phenylacetyl-CoA + glutamine => phenylacetyl glutamine + Coenzyme A TAS Homo sapiens 57287 R-HSA-184392 https://reactome.org/PathwayBrowser/#/R-HSA-184392 N-myristoylation of GAG polyprotein by NMT2 TAS Homo sapiens 57287 R-HSA-189442 https://reactome.org/PathwayBrowser/#/R-HSA-189442 ALAS condenses SUCC-CoA and Gly to form dALA TAS Homo sapiens 57287 R-HSA-191323 https://reactome.org/PathwayBrowser/#/R-HSA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA TAS Homo sapiens 57287 R-HSA-191352 https://reactome.org/PathwayBrowser/#/R-HSA-191352 HMGCR dimer reduces bHMG-CoA to MVA TAS Homo sapiens 57287 R-HSA-192137 https://reactome.org/PathwayBrowser/#/R-HSA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 57287 R-HSA-192312 https://reactome.org/PathwayBrowser/#/R-HSA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate TAS Homo sapiens 57287 R-HSA-192341 https://reactome.org/PathwayBrowser/#/R-HSA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA TAS Homo sapiens 57287 R-HSA-193385 https://reactome.org/PathwayBrowser/#/R-HSA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH TAS Homo sapiens 57287 R-HSA-193401 https://reactome.org/PathwayBrowser/#/R-HSA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 57287 R-HSA-193407 https://reactome.org/PathwayBrowser/#/R-HSA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 57287 R-HSA-193424 https://reactome.org/PathwayBrowser/#/R-HSA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 57287 R-HSA-193491 https://reactome.org/PathwayBrowser/#/R-HSA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate TAS Homo sapiens 57287 R-HSA-193533 https://reactome.org/PathwayBrowser/#/R-HSA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA TAS Homo sapiens 57287 R-HSA-193711 https://reactome.org/PathwayBrowser/#/R-HSA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 57287 R-HSA-193727 https://reactome.org/PathwayBrowser/#/R-HSA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 57287 R-HSA-193743 https://reactome.org/PathwayBrowser/#/R-HSA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 57287 R-HSA-193766 https://reactome.org/PathwayBrowser/#/R-HSA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 57287 R-HSA-196773 https://reactome.org/PathwayBrowser/#/R-HSA-196773 COASY phosphorylates DP-CoA TAS Homo sapiens 57287 R-HSA-196857 https://reactome.org/PathwayBrowser/#/R-HSA-196857 PANK2 phosphorylates PanK TAS Homo sapiens 57287 R-HSA-199202 https://reactome.org/PathwayBrowser/#/R-HSA-199202 Phosphopantetheine conjugation of the ACP domain of FAS TAS Homo sapiens 57287 R-HSA-199216 https://reactome.org/PathwayBrowser/#/R-HSA-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix TAS Homo sapiens 57287 R-HSA-200406 https://reactome.org/PathwayBrowser/#/R-HSA-200406 CPT1A,B transfers PALM to CAR TAS Homo sapiens 57287 R-HSA-200410 https://reactome.org/PathwayBrowser/#/R-HSA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine TAS Homo sapiens 57287 R-HSA-201035 https://reactome.org/PathwayBrowser/#/R-HSA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA TAS Homo sapiens 57287 R-HSA-2046083 https://reactome.org/PathwayBrowser/#/R-HSA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA TAS Homo sapiens 57287 R-HSA-2046085 https://reactome.org/PathwayBrowser/#/R-HSA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA TAS Homo sapiens 57287 R-HSA-2046088 https://reactome.org/PathwayBrowser/#/R-HSA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA TAS Homo sapiens 57287 R-HSA-2046090 https://reactome.org/PathwayBrowser/#/R-HSA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 57287 R-HSA-2046094 https://reactome.org/PathwayBrowser/#/R-HSA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA TAS Homo sapiens 57287 R-HSA-2046095 https://reactome.org/PathwayBrowser/#/R-HSA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA TAS Homo sapiens 57287 R-HSA-2046098 https://reactome.org/PathwayBrowser/#/R-HSA-2046098 Activation of linoleic acid to linoleoyl-CoA TAS Homo sapiens 57287 R-HSA-2046100 https://reactome.org/PathwayBrowser/#/R-HSA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA TAS Homo sapiens 57287 R-HSA-2066779 https://reactome.org/PathwayBrowser/#/R-HSA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) TAS Homo sapiens 57287 R-HSA-2066781 https://reactome.org/PathwayBrowser/#/R-HSA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) TAS Homo sapiens 57287 R-HSA-2066788 https://reactome.org/PathwayBrowser/#/R-HSA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase TAS Homo sapiens 57287 R-HSA-2090085 https://reactome.org/PathwayBrowser/#/R-HSA-2090085 HGSNAT oligomer acetylates Heparan chain(1) TAS Homo sapiens 57287 R-HSA-209792 https://reactome.org/PathwayBrowser/#/R-HSA-209792 N-acetylation of serotonin TAS Homo sapiens 57287 R-HSA-2465919 https://reactome.org/PathwayBrowser/#/R-HSA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM TAS Homo sapiens 57287 R-HSA-2468039 https://reactome.org/PathwayBrowser/#/R-HSA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 TAS Homo sapiens 57287 R-HSA-2473152 https://reactome.org/PathwayBrowser/#/R-HSA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 TAS Homo sapiens 57287 R-HSA-2534040 https://reactome.org/PathwayBrowser/#/R-HSA-2534040 Unknown NAT N-acylates Gly in GNAT1 IEA Homo sapiens 57287 R-HSA-2534087 https://reactome.org/PathwayBrowser/#/R-HSA-2534087 NMT1/2 transfer MYS to GNAT1 TAS Homo sapiens 57287 R-HSA-2545203 https://reactome.org/PathwayBrowser/#/R-HSA-2545203 Deacetylation of cleaved cohesin TAS Homo sapiens 57287 R-HSA-2545253 https://reactome.org/PathwayBrowser/#/R-HSA-2545253 Deacetylation of cohesin TAS Homo sapiens 57287 R-HSA-264622 https://reactome.org/PathwayBrowser/#/R-HSA-264622 Cho is acetylated to AcCho by CHAT TAS Homo sapiens 57287 R-HSA-3238694 https://reactome.org/PathwayBrowser/#/R-HSA-3238694 PORCN palmitoleoylates N-glycosyl WNTs IEA Homo sapiens 57287 R-HSA-3301237 https://reactome.org/PathwayBrowser/#/R-HSA-3301237 KAT2 complexes acetylate histone H3 IEA Homo sapiens 57287 R-HSA-3301345 https://reactome.org/PathwayBrowser/#/R-HSA-3301345 Elongator complex acetylates replicative histone H3, H4 IEA Homo sapiens 57287 R-HSA-3318413 https://reactome.org/PathwayBrowser/#/R-HSA-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 TAS Homo sapiens 57287 R-HSA-3318415 https://reactome.org/PathwayBrowser/#/R-HSA-3318415 ATF2 acetylates histone H2B, H4 TAS Homo sapiens 57287 R-HSA-3318486 https://reactome.org/PathwayBrowser/#/R-HSA-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 TAS Homo sapiens 57287 R-HSA-3321805 https://reactome.org/PathwayBrowser/#/R-HSA-3321805 NSL acetylates histone H4 TAS Homo sapiens 57287 R-HSA-3321883 https://reactome.org/PathwayBrowser/#/R-HSA-3321883 MSL acetylates histone H4 TAS Homo sapiens 57287 R-HSA-3321975 https://reactome.org/PathwayBrowser/#/R-HSA-3321975 NuA4 complex acetylates histone H2A, HIST1H4 IEA Homo sapiens 57287 R-HSA-3371554 https://reactome.org/PathwayBrowser/#/R-HSA-3371554 HSF1 acetylation at Lys80 TAS Homo sapiens 57287 R-HSA-3451147 https://reactome.org/PathwayBrowser/#/R-HSA-3451147 KAT5 HAT complex acetylates TCF4 gene at histone H4 IEA Homo sapiens 57287 R-HSA-351207 https://reactome.org/PathwayBrowser/#/R-HSA-351207 Spermine => N-acetylated spermine TAS Homo sapiens 57287 R-HSA-351208 https://reactome.org/PathwayBrowser/#/R-HSA-351208 Spermidine => N-acetylated spermidine TAS Homo sapiens 57287 R-HSA-3662318 https://reactome.org/PathwayBrowser/#/R-HSA-3662318 Type B histone acetlytransferase complex acetylates histone H4 TAS Homo sapiens 57287 R-HSA-3662335 https://reactome.org/PathwayBrowser/#/R-HSA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 TAS Homo sapiens 57287 R-HSA-3697008 https://reactome.org/PathwayBrowser/#/R-HSA-3697008 CREBBP acetylates histone H2B, H3, H4 IEA Homo sapiens 57287 R-HSA-3697920 https://reactome.org/PathwayBrowser/#/R-HSA-3697920 CLOCK acetylates lysine-10 of histone H3, H4 IEA Homo sapiens 57287 R-HSA-389580 https://reactome.org/PathwayBrowser/#/R-HSA-389580 formyl-CoA + H2O => formate + CoASH TAS Homo sapiens 57287 R-HSA-389622 https://reactome.org/PathwayBrowser/#/R-HSA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 57287 R-HSA-389632 https://reactome.org/PathwayBrowser/#/R-HSA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 57287 R-HSA-390224 https://reactome.org/PathwayBrowser/#/R-HSA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA TAS Homo sapiens 57287 R-HSA-390250 https://reactome.org/PathwayBrowser/#/R-HSA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA TAS Homo sapiens 57287 R-HSA-390276 https://reactome.org/PathwayBrowser/#/R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA TAS Homo sapiens 57287 R-HSA-390281 https://reactome.org/PathwayBrowser/#/R-HSA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH TAS Homo sapiens 57287 R-HSA-390284 https://reactome.org/PathwayBrowser/#/R-HSA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH TAS Homo sapiens 57287 R-HSA-390291 https://reactome.org/PathwayBrowser/#/R-HSA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH TAS Homo sapiens 57287 R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA TAS Homo sapiens 57287 R-HSA-390304 https://reactome.org/PathwayBrowser/#/R-HSA-390304 acetyl-CoA + H2O => acetate + CoASH TAS Homo sapiens 57287 R-HSA-390425 https://reactome.org/PathwayBrowser/#/R-HSA-390425 FAR1 reduces PalmCoA to HXOL TAS Homo sapiens 57287 R-HSA-390438 https://reactome.org/PathwayBrowser/#/R-HSA-390438 FAR2 reduces PalmCoA to HXOL TAS Homo sapiens 57287 R-HSA-428127 https://reactome.org/PathwayBrowser/#/R-HSA-428127 SPTLC complexes transfer acyl-CoA onto serine TAS Homo sapiens 57287 R-HSA-428185 https://reactome.org/PathwayBrowser/#/R-HSA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid TAS Homo sapiens 57287 R-HSA-434382 https://reactome.org/PathwayBrowser/#/R-HSA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell TAS Homo sapiens 57287 R-HSA-449734 https://reactome.org/PathwayBrowser/#/R-HSA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P TAS Homo sapiens 57287 R-HSA-449911 https://reactome.org/PathwayBrowser/#/R-HSA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] TAS Homo sapiens 57287 R-HSA-5144542 https://reactome.org/PathwayBrowser/#/R-HSA-5144542 CLOCK acetylates lysine-15 of histone H3, H4 IEA Homo sapiens 57287 R-HSA-5250938 https://reactome.org/PathwayBrowser/#/R-HSA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 TAS Homo sapiens 57287 R-HSA-5358343 https://reactome.org/PathwayBrowser/#/R-HSA-5358343 HHAT palmitoylates Hh N-terminal fragment TAS Homo sapiens 57287 R-HSA-5433066 https://reactome.org/PathwayBrowser/#/R-HSA-5433066 Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C TAS Homo sapiens 57287 R-HSA-548800 https://reactome.org/PathwayBrowser/#/R-HSA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA TAS Homo sapiens 57287 R-HSA-548814 https://reactome.org/PathwayBrowser/#/R-HSA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA TAS Homo sapiens 57287 R-HSA-548815 https://reactome.org/PathwayBrowser/#/R-HSA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA TAS Homo sapiens 57287 R-HSA-548830 https://reactome.org/PathwayBrowser/#/R-HSA-548830 ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA IEA Homo sapiens 57287 R-HSA-548843 https://reactome.org/PathwayBrowser/#/R-HSA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA TAS Homo sapiens 57287 R-HSA-549112 https://reactome.org/PathwayBrowser/#/R-HSA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 TAS Homo sapiens 57287 R-HSA-549192 https://reactome.org/PathwayBrowser/#/R-HSA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] TAS Homo sapiens 57287 R-HSA-5618328 https://reactome.org/PathwayBrowser/#/R-HSA-5618328 ATAT acetylates microtubules TAS Homo sapiens 57287 R-HSA-5618331 https://reactome.org/PathwayBrowser/#/R-HSA-5618331 HDAC6 deacetylates microtubules TAS Homo sapiens 57287 R-HSA-5628871 https://reactome.org/PathwayBrowser/#/R-HSA-5628871 BRD7 promotes EP300-mediated acetylation of TP53 TAS Homo sapiens 57287 R-HSA-5660660 https://reactome.org/PathwayBrowser/#/R-HSA-5660660 p300 acetylates RELA subunit TAS Homo sapiens 57287 R-HSA-5682044 https://reactome.org/PathwayBrowser/#/R-HSA-5682044 KAT5 acetylates ATM at DNA DSBs TAS Homo sapiens 57287 R-HSA-5682084 https://reactome.org/PathwayBrowser/#/R-HSA-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer TAS Homo sapiens 57287 R-HSA-5686304 https://reactome.org/PathwayBrowser/#/R-HSA-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 TAS Homo sapiens 57287 R-HSA-5690042 https://reactome.org/PathwayBrowser/#/R-HSA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 57287 R-HSA-5690043 https://reactome.org/PathwayBrowser/#/R-HSA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 57287 R-HSA-5690046 https://reactome.org/PathwayBrowser/#/R-HSA-5690046 PPT2 hydrolyses PALMCoA to PALM TAS Homo sapiens 57287 R-HSA-5690066 https://reactome.org/PathwayBrowser/#/R-HSA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 57287 R-HSA-5693001 https://reactome.org/PathwayBrowser/#/R-HSA-5693001 NAT8,8B acetylate BACE1 TAS Homo sapiens 57287 R-HSA-5694494 https://reactome.org/PathwayBrowser/#/R-HSA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA TAS Homo sapiens 57287 R-HSA-5695957 https://reactome.org/PathwayBrowser/#/R-HSA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA TAS Homo sapiens 57287 R-HSA-5696004 https://reactome.org/PathwayBrowser/#/R-HSA-5696004 ACSF2 ligates CoA-SH to MCFA TAS Homo sapiens 57287 R-HSA-5696007 https://reactome.org/PathwayBrowser/#/R-HSA-5696007 ACSF3 ligates CoA-SH to VLCFA TAS Homo sapiens 57287 R-HSA-5696424 https://reactome.org/PathwayBrowser/#/R-HSA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters TAS Homo sapiens 57287 R-HSA-5696448 https://reactome.org/PathwayBrowser/#/R-HSA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG TAS Homo sapiens 57287 R-HSA-6790987 https://reactome.org/PathwayBrowser/#/R-HSA-6790987 NAT10 acetylates cytidine-1337 and cytidine-1842 of 18S rRNA yielding 4-acetylcytidine-1377 and 4-acetylcytidine-1842 TAS Homo sapiens 57287 R-HSA-6792712 https://reactome.org/PathwayBrowser/#/R-HSA-6792712 KAT5 acetylates ATM at shortened telomeres TAS Homo sapiens 57287 R-HSA-6798345 https://reactome.org/PathwayBrowser/#/R-HSA-6798345 PXLP-GCAT dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA TAS Homo sapiens 57287 R-HSA-6800334 https://reactome.org/PathwayBrowser/#/R-HSA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG TAS Homo sapiens 57287 R-HSA-6805638 https://reactome.org/PathwayBrowser/#/R-HSA-6805638 KAT6A acetylates TP53 TAS Homo sapiens 57287 R-HSA-6809354 https://reactome.org/PathwayBrowser/#/R-HSA-6809354 NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT IEA Homo sapiens 57287 R-HSA-6811508 https://reactome.org/PathwayBrowser/#/R-HSA-6811508 ING2-bound EP300 acetylates TP53 TAS Homo sapiens 57287 R-HSA-6814090 https://reactome.org/PathwayBrowser/#/R-HSA-6814090 NatC acetylates ARFFRP1 IEA Homo sapiens 57287 R-HSA-70542 https://reactome.org/PathwayBrowser/#/R-HSA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA TAS Homo sapiens 57287 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 57287 R-HSA-70844 https://reactome.org/PathwayBrowser/#/R-HSA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA TAS Homo sapiens 57287 R-HSA-70881 https://reactome.org/PathwayBrowser/#/R-HSA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA TAS Homo sapiens 57287 R-HSA-70893 https://reactome.org/PathwayBrowser/#/R-HSA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ TAS Homo sapiens 57287 R-HSA-70975 https://reactome.org/PathwayBrowser/#/R-HSA-70975 CS acetylates OA to citrate TAS Homo sapiens 57287 R-HSA-70997 https://reactome.org/PathwayBrowser/#/R-HSA-70997 SUCLG1/A2 cleaves succinyl-CoA TAS Homo sapiens 57287 R-HSA-71037 https://reactome.org/PathwayBrowser/#/R-HSA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ TAS Homo sapiens 57287 R-HSA-71735 https://reactome.org/PathwayBrowser/#/R-HSA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] TAS Homo sapiens 57287 R-HSA-71775 https://reactome.org/PathwayBrowser/#/R-HSA-71775 SUCLG1/G2 cleaves succinyl-CoA TAS Homo sapiens 57287 R-HSA-73736 https://reactome.org/PathwayBrowser/#/R-HSA-73736 Acetylation of SL1 IEA Homo sapiens 57287 R-HSA-73916 https://reactome.org/PathwayBrowser/#/R-HSA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA TAS Homo sapiens 57287 R-HSA-73918 https://reactome.org/PathwayBrowser/#/R-HSA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH TAS Homo sapiens 57287 R-HSA-74181 https://reactome.org/PathwayBrowser/#/R-HSA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA TAS Homo sapiens 57287 R-HSA-75848 https://reactome.org/PathwayBrowser/#/R-HSA-75848 ACLY tetramer transforms CIT to Ac-CoA TAS Homo sapiens 57287 R-HSA-75872 https://reactome.org/PathwayBrowser/#/R-HSA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O TAS Homo sapiens 57287 R-HSA-75879 https://reactome.org/PathwayBrowser/#/R-HSA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH TAS Homo sapiens 57287 R-HSA-75885 https://reactome.org/PathwayBrowser/#/R-HSA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) TAS Homo sapiens 57287 R-HSA-75886 https://reactome.org/PathwayBrowser/#/R-HSA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] TAS Homo sapiens 57287 R-HSA-75900 https://reactome.org/PathwayBrowser/#/R-HSA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] TAS Homo sapiens 57287 R-HSA-77271 https://reactome.org/PathwayBrowser/#/R-HSA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA TAS Homo sapiens 57287 R-HSA-77304 https://reactome.org/PathwayBrowser/#/R-HSA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA TAS Homo sapiens 57287 R-HSA-77309 https://reactome.org/PathwayBrowser/#/R-HSA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA TAS Homo sapiens 57287 R-HSA-77321 https://reactome.org/PathwayBrowser/#/R-HSA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA TAS Homo sapiens 57287 R-HSA-77329 https://reactome.org/PathwayBrowser/#/R-HSA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA TAS Homo sapiens 57287 R-HSA-77340 https://reactome.org/PathwayBrowser/#/R-HSA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA TAS Homo sapiens 57287 R-HSA-8848215 https://reactome.org/PathwayBrowser/#/R-HSA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA TAS Homo sapiens 57287 R-HSA-8848580 https://reactome.org/PathwayBrowser/#/R-HSA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG TAS Homo sapiens 57287 R-HSA-8848582 https://reactome.org/PathwayBrowser/#/R-HSA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester TAS Homo sapiens 57287 R-HSA-8848585 https://reactome.org/PathwayBrowser/#/R-HSA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM TAS Homo sapiens 57287 R-HSA-8849345 https://reactome.org/PathwayBrowser/#/R-HSA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine TAS Homo sapiens 57287 R-HSA-8874745 https://reactome.org/PathwayBrowser/#/R-HSA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH TAS Homo sapiens 57287 R-HSA-8875071 https://reactome.org/PathwayBrowser/#/R-HSA-8875071 ACSS3 ligates CoA to CH3COO- TAS Homo sapiens 57287 R-HSA-8875077 https://reactome.org/PathwayBrowser/#/R-HSA-8875077 SLC27A3 ligates CoA-SH to VLCFA IEA Homo sapiens 57287 R-HSA-8876696 https://reactome.org/PathwayBrowser/#/R-HSA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST TAS Homo sapiens 57287 R-HSA-8933547 https://reactome.org/PathwayBrowser/#/R-HSA-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 TAS Homo sapiens 57287 R-HSA-8938314 https://reactome.org/PathwayBrowser/#/R-HSA-8938314 ENPPs hydrolyse CoA-SH to PPANT, PAP TAS Homo sapiens 57287 R-HSA-8951966 https://reactome.org/PathwayBrowser/#/R-HSA-8951966 EP300 acetylates RUNX3 TAS Homo sapiens 57287 R-HSA-8954468 https://reactome.org/PathwayBrowser/#/R-HSA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA TAS Homo sapiens 57287 R-HSA-9021072 https://reactome.org/PathwayBrowser/#/R-HSA-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 TAS Homo sapiens 57287 R-HSA-9614810 https://reactome.org/PathwayBrowser/#/R-HSA-9614810 Activation of Latent HCMV Genome TAS Homo sapiens 57287 R-HSA-9617758 https://reactome.org/PathwayBrowser/#/R-HSA-9617758 EP300,CREBBP acetylate FOXO4 IEA Homo sapiens 57287 R-HSA-9620515 https://reactome.org/PathwayBrowser/#/R-HSA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress TAS Homo sapiens 57287 R-HSA-9626945 https://reactome.org/PathwayBrowser/#/R-HSA-9626945 CREBBP acetylates FOXO1 IEA Homo sapiens 57287 R-HSA-9636560 https://reactome.org/PathwayBrowser/#/R-HSA-9636560 Eis acetylates DUSP16 TAS Homo sapiens 57287 R-HSA-9647982 https://reactome.org/PathwayBrowser/#/R-HSA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated TAS Homo sapiens 57287 R-HSA-9683653 https://reactome.org/PathwayBrowser/#/R-HSA-9683653 Spike protein gets palmitoylated TAS Homo sapiens 57287 R-HSA-9683720 https://reactome.org/PathwayBrowser/#/R-HSA-9683720 E protein gets palmitoylated TAS Homo sapiens 57287 R-HSA-9694341 https://reactome.org/PathwayBrowser/#/R-HSA-9694341 Spike protein gets palmitoylated TAS Homo sapiens 57287 R-HSA-9694401 https://reactome.org/PathwayBrowser/#/R-HSA-9694401 E protein gets palmitoylated IEA Homo sapiens 57287 R-HSA-9701531 https://reactome.org/PathwayBrowser/#/R-HSA-9701531 p-Y705,S727 STAT3 is acetylated TAS Homo sapiens 57287 R-HSA-9734535 https://reactome.org/PathwayBrowser/#/R-HSA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA TAS Homo sapiens 57287 R-HSA-9749971 https://reactome.org/PathwayBrowser/#/R-HSA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA TAS Homo sapiens 57287 R-HSA-9750001 https://reactome.org/PathwayBrowser/#/R-HSA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid TAS Homo sapiens 57287 R-HSA-9753676 https://reactome.org/PathwayBrowser/#/R-HSA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer TAS Homo sapiens 57287 R-HSA-9756494 https://reactome.org/PathwayBrowser/#/R-HSA-9756494 CREBBP acetylates SARS-CoV-2 N at K375 TAS Homo sapiens 57287 R-HSA-9760081 https://reactome.org/PathwayBrowser/#/R-HSA-9760081 CREBBP, EP300 acetylates NFE2L2 TAS Homo sapiens 57287 R-HSA-9825747 https://reactome.org/PathwayBrowser/#/R-HSA-9825747 CREBBP acetylates HINT1 dimer TAS Homo sapiens 57287 R-HSA-9829047 https://reactome.org/PathwayBrowser/#/R-HSA-9829047 F0 is palmitoylated TAS Homo sapiens 57287 R-HSA-9830875 https://reactome.org/PathwayBrowser/#/R-HSA-9830875 G is palmitoylated TAS Homo sapiens 57287 R-HSA-9837333 https://reactome.org/PathwayBrowser/#/R-HSA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP TAS Homo sapiens 57287 R-HSA-9837337 https://reactome.org/PathwayBrowser/#/R-HSA-9837337 DCAKD phosphorylates DP-CoA TAS Homo sapiens 57287 R-HSA-9837354 https://reactome.org/PathwayBrowser/#/R-HSA-9837354 NUDT8 hydrolyzes CoA-SH to PPANT IEA Homo sapiens 57287 R-HSA-9853512 https://reactome.org/PathwayBrowser/#/R-HSA-9853512 DLST transfers succinyl to CoA TAS Homo sapiens 57287 R-HSA-9854415 https://reactome.org/PathwayBrowser/#/R-HSA-9854415 ACAT1 tetramer acetylates IDH2 dimer TAS Homo sapiens 57287 R-HSA-9861667 https://reactome.org/PathwayBrowser/#/R-HSA-9861667 DLAT trimer transfers acetyl to CoA TAS Homo sapiens 57287 R-MMU-1482533 https://reactome.org/PathwayBrowser/#/R-MMU-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Mus musculus 57287 R-MMU-1482539 https://reactome.org/PathwayBrowser/#/R-MMU-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Mus musculus 57287 R-MMU-1482546 https://reactome.org/PathwayBrowser/#/R-MMU-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Mus musculus 57287 R-MMU-1482547 https://reactome.org/PathwayBrowser/#/R-MMU-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Mus musculus 57287 R-MMU-1482548 https://reactome.org/PathwayBrowser/#/R-MMU-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Mus musculus 57287 R-MMU-1482598 https://reactome.org/PathwayBrowser/#/R-MMU-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Mus musculus 57287 R-MMU-1482626 https://reactome.org/PathwayBrowser/#/R-MMU-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Mus musculus 57287 R-MMU-1482635 https://reactome.org/PathwayBrowser/#/R-MMU-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Mus musculus 57287 R-MMU-1482636 https://reactome.org/PathwayBrowser/#/R-MMU-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Mus musculus 57287 R-MMU-1482646 https://reactome.org/PathwayBrowser/#/R-MMU-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Mus musculus 57287 R-MMU-1482667 https://reactome.org/PathwayBrowser/#/R-MMU-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Mus musculus 57287 R-MMU-1482689 https://reactome.org/PathwayBrowser/#/R-MMU-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Mus musculus 57287 R-MMU-1482691 https://reactome.org/PathwayBrowser/#/R-MMU-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Mus musculus 57287 R-MMU-1482695 https://reactome.org/PathwayBrowser/#/R-MMU-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Mus musculus 57287 R-MMU-1482775 https://reactome.org/PathwayBrowser/#/R-MMU-1482775 MLCL is acylated to CL by HADH (IM) IEA Mus musculus 57287 R-MMU-1482861 https://reactome.org/PathwayBrowser/#/R-MMU-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Mus musculus 57287 R-MMU-1482867 https://reactome.org/PathwayBrowser/#/R-MMU-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Mus musculus 57287 R-MMU-1482889 https://reactome.org/PathwayBrowser/#/R-MMU-1482889 DAG is acylated to TAG by DGAT1/2 IEA Mus musculus 57287 R-MMU-1483002 https://reactome.org/PathwayBrowser/#/R-MMU-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Mus musculus 57287 R-MMU-158832 https://reactome.org/PathwayBrowser/#/R-MMU-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Mus musculus 57287 R-MMU-159425 https://reactome.org/PathwayBrowser/#/R-MMU-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 57287 R-MMU-159431 https://reactome.org/PathwayBrowser/#/R-MMU-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Mus musculus 57287 R-MMU-159443 https://reactome.org/PathwayBrowser/#/R-MMU-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Mus musculus 57287 R-MMU-159566 https://reactome.org/PathwayBrowser/#/R-MMU-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Mus musculus 57287 R-MMU-159567 https://reactome.org/PathwayBrowser/#/R-MMU-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Mus musculus 57287 R-MMU-159574 https://reactome.org/PathwayBrowser/#/R-MMU-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Mus musculus 57287 R-MMU-162683 https://reactome.org/PathwayBrowser/#/R-MMU-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Mus musculus 57287 R-MMU-1678660 https://reactome.org/PathwayBrowser/#/R-MMU-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Mus musculus 57287 R-MMU-174959 https://reactome.org/PathwayBrowser/#/R-MMU-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Mus musculus 57287 R-MMU-177157 https://reactome.org/PathwayBrowser/#/R-MMU-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Mus musculus 57287 R-MMU-189442 https://reactome.org/PathwayBrowser/#/R-MMU-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Mus musculus 57287 R-MMU-191323 https://reactome.org/PathwayBrowser/#/R-MMU-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Mus musculus 57287 R-MMU-191352 https://reactome.org/PathwayBrowser/#/R-MMU-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Mus musculus 57287 R-MMU-192137 https://reactome.org/PathwayBrowser/#/R-MMU-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 57287 R-MMU-192312 https://reactome.org/PathwayBrowser/#/R-MMU-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Mus musculus 57287 R-MMU-192341 https://reactome.org/PathwayBrowser/#/R-MMU-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Mus musculus 57287 R-MMU-193385 https://reactome.org/PathwayBrowser/#/R-MMU-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Mus musculus 57287 R-MMU-193401 https://reactome.org/PathwayBrowser/#/R-MMU-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 57287 R-MMU-193407 https://reactome.org/PathwayBrowser/#/R-MMU-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 57287 R-MMU-193424 https://reactome.org/PathwayBrowser/#/R-MMU-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 57287 R-MMU-193491 https://reactome.org/PathwayBrowser/#/R-MMU-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Mus musculus 57287 R-MMU-193533 https://reactome.org/PathwayBrowser/#/R-MMU-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Mus musculus 57287 R-MMU-193711 https://reactome.org/PathwayBrowser/#/R-MMU-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 57287 R-MMU-193727 https://reactome.org/PathwayBrowser/#/R-MMU-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 57287 R-MMU-193743 https://reactome.org/PathwayBrowser/#/R-MMU-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 57287 R-MMU-193766 https://reactome.org/PathwayBrowser/#/R-MMU-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 57287 R-MMU-196773 https://reactome.org/PathwayBrowser/#/R-MMU-196773 COASY phosphorylates DP-CoA IEA Mus musculus 57287 R-MMU-196857 https://reactome.org/PathwayBrowser/#/R-MMU-196857 PANK2 phosphorylates PanK IEA Mus musculus 57287 R-MMU-199202 https://reactome.org/PathwayBrowser/#/R-MMU-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Mus musculus 57287 R-MMU-199216 https://reactome.org/PathwayBrowser/#/R-MMU-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Mus musculus 57287 R-MMU-200406 https://reactome.org/PathwayBrowser/#/R-MMU-200406 CPT1A,B transfers PALM to CAR IEA Mus musculus 57287 R-MMU-200410 https://reactome.org/PathwayBrowser/#/R-MMU-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Mus musculus 57287 R-MMU-201035 https://reactome.org/PathwayBrowser/#/R-MMU-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Mus musculus 57287 R-MMU-2046083 https://reactome.org/PathwayBrowser/#/R-MMU-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Mus musculus 57287 R-MMU-2046085 https://reactome.org/PathwayBrowser/#/R-MMU-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Mus musculus 57287 R-MMU-2046088 https://reactome.org/PathwayBrowser/#/R-MMU-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Mus musculus 57287 R-MMU-2046090 https://reactome.org/PathwayBrowser/#/R-MMU-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 57287 R-MMU-2046094 https://reactome.org/PathwayBrowser/#/R-MMU-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Mus musculus 57287 R-MMU-2046095 https://reactome.org/PathwayBrowser/#/R-MMU-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Mus musculus 57287 R-MMU-2046098 https://reactome.org/PathwayBrowser/#/R-MMU-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Mus musculus 57287 R-MMU-2046100 https://reactome.org/PathwayBrowser/#/R-MMU-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Mus musculus 57287 R-MMU-2066779 https://reactome.org/PathwayBrowser/#/R-MMU-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Mus musculus 57287 R-MMU-2066781 https://reactome.org/PathwayBrowser/#/R-MMU-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Mus musculus 57287 R-MMU-2066788 https://reactome.org/PathwayBrowser/#/R-MMU-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Mus musculus 57287 R-MMU-2090085 https://reactome.org/PathwayBrowser/#/R-MMU-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Mus musculus 57287 R-MMU-209792 https://reactome.org/PathwayBrowser/#/R-MMU-209792 N-acetylation of serotonin IEA Mus musculus 57287 R-MMU-2465919 https://reactome.org/PathwayBrowser/#/R-MMU-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Mus musculus 57287 R-MMU-2468039 https://reactome.org/PathwayBrowser/#/R-MMU-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Mus musculus 57287 R-MMU-2473152 https://reactome.org/PathwayBrowser/#/R-MMU-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Mus musculus 57287 R-MMU-2534087 https://reactome.org/PathwayBrowser/#/R-MMU-2534087 NMT1/2 transfer MYS to GNAT1 IEA Mus musculus 57287 R-MMU-2545203 https://reactome.org/PathwayBrowser/#/R-MMU-2545203 Deacetylation of cleaved cohesin IEA Mus musculus 57287 R-MMU-2545253 https://reactome.org/PathwayBrowser/#/R-MMU-2545253 Deacetylation of cohesin IEA Mus musculus 57287 R-MMU-264622 https://reactome.org/PathwayBrowser/#/R-MMU-264622 Cho is acetylated to AcCho by CHAT IEA Mus musculus 57287 R-MMU-3238687 https://reactome.org/PathwayBrowser/#/R-MMU-3238687 PORCN palmitoleoylates WNT3a TAS Mus musculus 57287 R-MMU-3318413 https://reactome.org/PathwayBrowser/#/R-MMU-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Mus musculus 57287 R-MMU-3318415 https://reactome.org/PathwayBrowser/#/R-MMU-3318415 ATF2 acetylates histone H2B, H4 IEA Mus musculus 57287 R-MMU-3318486 https://reactome.org/PathwayBrowser/#/R-MMU-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Mus musculus 57287 R-MMU-3321805 https://reactome.org/PathwayBrowser/#/R-MMU-3321805 NSL acetylates histone H4 IEA Mus musculus 57287 R-MMU-3321883 https://reactome.org/PathwayBrowser/#/R-MMU-3321883 MSL acetylates histone H4 IEA Mus musculus 57287 R-MMU-3371554 https://reactome.org/PathwayBrowser/#/R-MMU-3371554 HSF1 acetylation at Lys80 IEA Mus musculus 57287 R-MMU-351207 https://reactome.org/PathwayBrowser/#/R-MMU-351207 Spermine => N-acetylated spermine IEA Mus musculus 57287 R-MMU-351208 https://reactome.org/PathwayBrowser/#/R-MMU-351208 Spermidine => N-acetylated spermidine IEA Mus musculus 57287 R-MMU-3662318 https://reactome.org/PathwayBrowser/#/R-MMU-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Mus musculus 57287 R-MMU-389622 https://reactome.org/PathwayBrowser/#/R-MMU-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 57287 R-MMU-389632 https://reactome.org/PathwayBrowser/#/R-MMU-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 57287 R-MMU-390224 https://reactome.org/PathwayBrowser/#/R-MMU-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Mus musculus 57287 R-MMU-390250 https://reactome.org/PathwayBrowser/#/R-MMU-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Mus musculus 57287 R-MMU-390281 https://reactome.org/PathwayBrowser/#/R-MMU-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Mus musculus 57287 R-MMU-390284 https://reactome.org/PathwayBrowser/#/R-MMU-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Mus musculus 57287 R-MMU-390291 https://reactome.org/PathwayBrowser/#/R-MMU-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Mus musculus 57287 R-MMU-390304 https://reactome.org/PathwayBrowser/#/R-MMU-390304 acetyl-CoA + H2O => acetate + CoASH IEA Mus musculus 57287 R-MMU-390425 https://reactome.org/PathwayBrowser/#/R-MMU-390425 FAR1 reduces PalmCoA to HXOL IEA Mus musculus 57287 R-MMU-390438 https://reactome.org/PathwayBrowser/#/R-MMU-390438 FAR2 reduces PalmCoA to HXOL IEA Mus musculus 57287 R-MMU-428127 https://reactome.org/PathwayBrowser/#/R-MMU-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Mus musculus 57287 R-MMU-428185 https://reactome.org/PathwayBrowser/#/R-MMU-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Mus musculus 57287 R-MMU-434382 https://reactome.org/PathwayBrowser/#/R-MMU-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Mus musculus 57287 R-MMU-449734 https://reactome.org/PathwayBrowser/#/R-MMU-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Mus musculus 57287 R-MMU-449911 https://reactome.org/PathwayBrowser/#/R-MMU-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Mus musculus 57287 R-MMU-5211235 https://reactome.org/PathwayBrowser/#/R-MMU-5211235 Kat2b (Pcaf) acetylates Taf1b in SL1 Complex TAS Mus musculus 57287 R-MMU-5358343 https://reactome.org/PathwayBrowser/#/R-MMU-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Mus musculus 57287 R-MMU-548800 https://reactome.org/PathwayBrowser/#/R-MMU-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Mus musculus 57287 R-MMU-548814 https://reactome.org/PathwayBrowser/#/R-MMU-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Mus musculus 57287 R-MMU-548815 https://reactome.org/PathwayBrowser/#/R-MMU-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Mus musculus 57287 R-MMU-548843 https://reactome.org/PathwayBrowser/#/R-MMU-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Mus musculus 57287 R-MMU-548848 https://reactome.org/PathwayBrowser/#/R-MMU-548848 lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4] TAS Mus musculus 57287 R-MMU-549112 https://reactome.org/PathwayBrowser/#/R-MMU-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Mus musculus 57287 R-MMU-549192 https://reactome.org/PathwayBrowser/#/R-MMU-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Mus musculus 57287 R-MMU-5618328 https://reactome.org/PathwayBrowser/#/R-MMU-5618328 ATAT acetylates microtubules IEA Mus musculus 57287 R-MMU-5618331 https://reactome.org/PathwayBrowser/#/R-MMU-5618331 HDAC6 deacetylates microtubules IEA Mus musculus 57287 R-MMU-5628871 https://reactome.org/PathwayBrowser/#/R-MMU-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Mus musculus 57287 R-MMU-5660660 https://reactome.org/PathwayBrowser/#/R-MMU-5660660 p300 acetylates RELA subunit IEA Mus musculus 57287 R-MMU-5682044 https://reactome.org/PathwayBrowser/#/R-MMU-5682044 KAT5 acetylates ATM at DNA DSBs IEA Mus musculus 57287 R-MMU-5682084 https://reactome.org/PathwayBrowser/#/R-MMU-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Mus musculus 57287 R-MMU-5686304 https://reactome.org/PathwayBrowser/#/R-MMU-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Mus musculus 57287 R-MMU-5690042 https://reactome.org/PathwayBrowser/#/R-MMU-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 57287 R-MMU-5690043 https://reactome.org/PathwayBrowser/#/R-MMU-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 57287 R-MMU-5690046 https://reactome.org/PathwayBrowser/#/R-MMU-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Mus musculus 57287 R-MMU-5690066 https://reactome.org/PathwayBrowser/#/R-MMU-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 57287 R-MMU-5694494 https://reactome.org/PathwayBrowser/#/R-MMU-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Mus musculus 57287 R-MMU-5695957 https://reactome.org/PathwayBrowser/#/R-MMU-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Mus musculus 57287 R-MMU-5696004 https://reactome.org/PathwayBrowser/#/R-MMU-5696004 ACSF2 ligates CoA-SH to MCFA IEA Mus musculus 57287 R-MMU-5696007 https://reactome.org/PathwayBrowser/#/R-MMU-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Mus musculus 57287 R-MMU-5696424 https://reactome.org/PathwayBrowser/#/R-MMU-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Mus musculus 57287 R-MMU-5696448 https://reactome.org/PathwayBrowser/#/R-MMU-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Mus musculus 57287 R-MMU-6792712 https://reactome.org/PathwayBrowser/#/R-MMU-6792712 KAT5 acetylates ATM at shortened telomeres IEA Mus musculus 57287 R-MMU-6800334 https://reactome.org/PathwayBrowser/#/R-MMU-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Mus musculus 57287 R-MMU-6805638 https://reactome.org/PathwayBrowser/#/R-MMU-6805638 KAT6A acetylates TP53 IEA Mus musculus 57287 R-MMU-6810452 https://reactome.org/PathwayBrowser/#/R-MMU-6810452 Nudt7 hydrolyses CoA-SH to 3',5'-ADP and PPANT TAS Mus musculus 57287 R-MMU-6811508 https://reactome.org/PathwayBrowser/#/R-MMU-6811508 ING2-bound EP300 acetylates TP53 IEA Mus musculus 57287 R-MMU-70542 https://reactome.org/PathwayBrowser/#/R-MMU-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Mus musculus 57287 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 57287 R-MMU-70844 https://reactome.org/PathwayBrowser/#/R-MMU-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Mus musculus 57287 R-MMU-70881 https://reactome.org/PathwayBrowser/#/R-MMU-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Mus musculus 57287 R-MMU-70893 https://reactome.org/PathwayBrowser/#/R-MMU-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Mus musculus 57287 R-MMU-70975 https://reactome.org/PathwayBrowser/#/R-MMU-70975 CS acetylates OA to citrate IEA Mus musculus 57287 R-MMU-70997 https://reactome.org/PathwayBrowser/#/R-MMU-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Mus musculus 57287 R-MMU-71037 https://reactome.org/PathwayBrowser/#/R-MMU-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Mus musculus 57287 R-MMU-71735 https://reactome.org/PathwayBrowser/#/R-MMU-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Mus musculus 57287 R-MMU-71775 https://reactome.org/PathwayBrowser/#/R-MMU-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Mus musculus 57287 R-MMU-73916 https://reactome.org/PathwayBrowser/#/R-MMU-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Mus musculus 57287 R-MMU-73918 https://reactome.org/PathwayBrowser/#/R-MMU-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Mus musculus 57287 R-MMU-74181 https://reactome.org/PathwayBrowser/#/R-MMU-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Mus musculus 57287 R-MMU-75848 https://reactome.org/PathwayBrowser/#/R-MMU-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Mus musculus 57287 R-MMU-75872 https://reactome.org/PathwayBrowser/#/R-MMU-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Mus musculus 57287 R-MMU-75879 https://reactome.org/PathwayBrowser/#/R-MMU-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Mus musculus 57287 R-MMU-75885 https://reactome.org/PathwayBrowser/#/R-MMU-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Mus musculus 57287 R-MMU-75886 https://reactome.org/PathwayBrowser/#/R-MMU-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Mus musculus 57287 R-MMU-75900 https://reactome.org/PathwayBrowser/#/R-MMU-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Mus musculus 57287 R-MMU-77271 https://reactome.org/PathwayBrowser/#/R-MMU-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Mus musculus 57287 R-MMU-77304 https://reactome.org/PathwayBrowser/#/R-MMU-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Mus musculus 57287 R-MMU-77309 https://reactome.org/PathwayBrowser/#/R-MMU-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Mus musculus 57287 R-MMU-77321 https://reactome.org/PathwayBrowser/#/R-MMU-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Mus musculus 57287 R-MMU-77329 https://reactome.org/PathwayBrowser/#/R-MMU-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Mus musculus 57287 R-MMU-77340 https://reactome.org/PathwayBrowser/#/R-MMU-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Mus musculus 57287 R-MMU-8848215 https://reactome.org/PathwayBrowser/#/R-MMU-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Mus musculus 57287 R-MMU-8848580 https://reactome.org/PathwayBrowser/#/R-MMU-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Mus musculus 57287 R-MMU-8848582 https://reactome.org/PathwayBrowser/#/R-MMU-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Mus musculus 57287 R-MMU-8848585 https://reactome.org/PathwayBrowser/#/R-MMU-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Mus musculus 57287 R-MMU-8849345 https://reactome.org/PathwayBrowser/#/R-MMU-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Mus musculus 57287 R-MMU-8874745 https://reactome.org/PathwayBrowser/#/R-MMU-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Mus musculus 57287 R-MMU-8875071 https://reactome.org/PathwayBrowser/#/R-MMU-8875071 ACSS3 ligates CoA to CH3COO- IEA Mus musculus 57287 R-MMU-8875095 https://reactome.org/PathwayBrowser/#/R-MMU-8875095 Slc27a3 ligates CoA to VLCFA TAS Mus musculus 57287 R-MMU-8876696 https://reactome.org/PathwayBrowser/#/R-MMU-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Mus musculus 57287 R-MMU-8933547 https://reactome.org/PathwayBrowser/#/R-MMU-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Mus musculus 57287 R-MMU-8951966 https://reactome.org/PathwayBrowser/#/R-MMU-8951966 EP300 acetylates RUNX3 IEA Mus musculus 57287 R-MMU-8954468 https://reactome.org/PathwayBrowser/#/R-MMU-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Mus musculus 57287 R-MMU-9021072 https://reactome.org/PathwayBrowser/#/R-MMU-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Mus musculus 57287 R-MMU-9617755 https://reactome.org/PathwayBrowser/#/R-MMU-9617755 Crebbp acetylates Foxo4 TAS Mus musculus 57287 R-MMU-9620515 https://reactome.org/PathwayBrowser/#/R-MMU-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Mus musculus 57287 R-MMU-9647982 https://reactome.org/PathwayBrowser/#/R-MMU-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Mus musculus 57287 R-MMU-9701531 https://reactome.org/PathwayBrowser/#/R-MMU-9701531 p-Y705,S727 STAT3 is acetylated IEA Mus musculus 57287 R-MMU-9734535 https://reactome.org/PathwayBrowser/#/R-MMU-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Mus musculus 57287 R-MMU-9749971 https://reactome.org/PathwayBrowser/#/R-MMU-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Mus musculus 57287 R-MMU-9750001 https://reactome.org/PathwayBrowser/#/R-MMU-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Mus musculus 57287 R-MMU-9753676 https://reactome.org/PathwayBrowser/#/R-MMU-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Mus musculus 57287 R-MMU-9760081 https://reactome.org/PathwayBrowser/#/R-MMU-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Mus musculus 57287 R-MMU-9825747 https://reactome.org/PathwayBrowser/#/R-MMU-9825747 CREBBP acetylates HINT1 dimer IEA Mus musculus 57287 R-MMU-9837333 https://reactome.org/PathwayBrowser/#/R-MMU-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Mus musculus 57287 R-MMU-9837337 https://reactome.org/PathwayBrowser/#/R-MMU-9837337 DCAKD phosphorylates DP-CoA IEA Mus musculus 57287 R-MMU-9837342 https://reactome.org/PathwayBrowser/#/R-MMU-9837342 Nudt8 hydrolyzes CoA-SH to PPANT TAS Mus musculus 57287 R-MMU-9853512 https://reactome.org/PathwayBrowser/#/R-MMU-9853512 DLST transfers succinyl to CoA IEA Mus musculus 57287 R-MMU-9854415 https://reactome.org/PathwayBrowser/#/R-MMU-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Mus musculus 57287 R-MMU-9861667 https://reactome.org/PathwayBrowser/#/R-MMU-9861667 DLAT trimer transfers acetyl to CoA IEA Mus musculus 57287 R-MTU-879248 https://reactome.org/PathwayBrowser/#/R-MTU-879248 desacetylmycothiol is acetylated to mycothiol using acetyl-CoA TAS Mycobacterium tuberculosis 57287 R-MTU-936615 https://reactome.org/PathwayBrowser/#/R-MTU-936615 acetylation of serine TAS Mycobacterium tuberculosis 57287 R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 57287 R-NUL-3451144 https://reactome.org/PathwayBrowser/#/R-NUL-3451144 KAT5 HAT complex acetylates TCF4 (ITF-2) gene at histone H4 TAS Homo sapiens 57287 R-NUL-9617757 https://reactome.org/PathwayBrowser/#/R-NUL-9617757 EP300 acetylates Foxo4 TAS Homo sapiens 57287 R-NUL-9626944 https://reactome.org/PathwayBrowser/#/R-NUL-9626944 CREBBP acetylates Foxo1 TAS Homo sapiens 57287 R-PFA-1482533 https://reactome.org/PathwayBrowser/#/R-PFA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Plasmodium falciparum 57287 R-PFA-1482539 https://reactome.org/PathwayBrowser/#/R-PFA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Plasmodium falciparum 57287 R-PFA-1482547 https://reactome.org/PathwayBrowser/#/R-PFA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Plasmodium falciparum 57287 R-PFA-1482635 https://reactome.org/PathwayBrowser/#/R-PFA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Plasmodium falciparum 57287 R-PFA-1482636 https://reactome.org/PathwayBrowser/#/R-PFA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Plasmodium falciparum 57287 R-PFA-1482646 https://reactome.org/PathwayBrowser/#/R-PFA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Plasmodium falciparum 57287 R-PFA-1482667 https://reactome.org/PathwayBrowser/#/R-PFA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Plasmodium falciparum 57287 R-PFA-1482691 https://reactome.org/PathwayBrowser/#/R-PFA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Plasmodium falciparum 57287 R-PFA-1482889 https://reactome.org/PathwayBrowser/#/R-PFA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Plasmodium falciparum 57287 R-PFA-162683 https://reactome.org/PathwayBrowser/#/R-PFA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Plasmodium falciparum 57287 R-PFA-189442 https://reactome.org/PathwayBrowser/#/R-PFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Plasmodium falciparum 57287 R-PFA-199216 https://reactome.org/PathwayBrowser/#/R-PFA-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Plasmodium falciparum 57287 R-PFA-201035 https://reactome.org/PathwayBrowser/#/R-PFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Plasmodium falciparum 57287 R-PFA-2046085 https://reactome.org/PathwayBrowser/#/R-PFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Plasmodium falciparum 57287 R-PFA-2046088 https://reactome.org/PathwayBrowser/#/R-PFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Plasmodium falciparum 57287 R-PFA-2046094 https://reactome.org/PathwayBrowser/#/R-PFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Plasmodium falciparum 57287 R-PFA-2046098 https://reactome.org/PathwayBrowser/#/R-PFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Plasmodium falciparum 57287 R-PFA-3662318 https://reactome.org/PathwayBrowser/#/R-PFA-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Plasmodium falciparum 57287 R-PFA-428185 https://reactome.org/PathwayBrowser/#/R-PFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Plasmodium falciparum 57287 R-PFA-449911 https://reactome.org/PathwayBrowser/#/R-PFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Plasmodium falciparum 57287 R-PFA-548800 https://reactome.org/PathwayBrowser/#/R-PFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Plasmodium falciparum 57287 R-PFA-548814 https://reactome.org/PathwayBrowser/#/R-PFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Plasmodium falciparum 57287 R-PFA-5618328 https://reactome.org/PathwayBrowser/#/R-PFA-5618328 ATAT acetylates microtubules IEA Plasmodium falciparum 57287 R-PFA-5618331 https://reactome.org/PathwayBrowser/#/R-PFA-5618331 HDAC6 deacetylates microtubules IEA Plasmodium falciparum 57287 R-PFA-5690066 https://reactome.org/PathwayBrowser/#/R-PFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Plasmodium falciparum 57287 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 57287 R-PFA-70844 https://reactome.org/PathwayBrowser/#/R-PFA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Plasmodium falciparum 57287 R-PFA-70881 https://reactome.org/PathwayBrowser/#/R-PFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Plasmodium falciparum 57287 R-PFA-70975 https://reactome.org/PathwayBrowser/#/R-PFA-70975 CS acetylates OA to citrate IEA Plasmodium falciparum 57287 R-PFA-70997 https://reactome.org/PathwayBrowser/#/R-PFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Plasmodium falciparum 57287 R-PFA-71735 https://reactome.org/PathwayBrowser/#/R-PFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Plasmodium falciparum 57287 R-PFA-71775 https://reactome.org/PathwayBrowser/#/R-PFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Plasmodium falciparum 57287 R-PFA-73916 https://reactome.org/PathwayBrowser/#/R-PFA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Plasmodium falciparum 57287 R-PFA-74181 https://reactome.org/PathwayBrowser/#/R-PFA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Plasmodium falciparum 57287 R-PFA-75885 https://reactome.org/PathwayBrowser/#/R-PFA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Plasmodium falciparum 57287 R-PFA-75900 https://reactome.org/PathwayBrowser/#/R-PFA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Plasmodium falciparum 57287 R-PFA-8848215 https://reactome.org/PathwayBrowser/#/R-PFA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Plasmodium falciparum 57287 R-PFA-8954468 https://reactome.org/PathwayBrowser/#/R-PFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Plasmodium falciparum 57287 R-PFA-9837333 https://reactome.org/PathwayBrowser/#/R-PFA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Plasmodium falciparum 57287 R-PFA-9837337 https://reactome.org/PathwayBrowser/#/R-PFA-9837337 DCAKD phosphorylates DP-CoA IEA Plasmodium falciparum 57287 R-PFA-9853512 https://reactome.org/PathwayBrowser/#/R-PFA-9853512 DLST transfers succinyl to CoA IEA Plasmodium falciparum 57287 R-PFA-9854415 https://reactome.org/PathwayBrowser/#/R-PFA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Plasmodium falciparum 57287 R-RNO-1482533 https://reactome.org/PathwayBrowser/#/R-RNO-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Rattus norvegicus 57287 R-RNO-1482539 https://reactome.org/PathwayBrowser/#/R-RNO-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Rattus norvegicus 57287 R-RNO-1482546 https://reactome.org/PathwayBrowser/#/R-RNO-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Rattus norvegicus 57287 R-RNO-1482547 https://reactome.org/PathwayBrowser/#/R-RNO-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Rattus norvegicus 57287 R-RNO-1482548 https://reactome.org/PathwayBrowser/#/R-RNO-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Rattus norvegicus 57287 R-RNO-1482635 https://reactome.org/PathwayBrowser/#/R-RNO-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Rattus norvegicus 57287 R-RNO-1482636 https://reactome.org/PathwayBrowser/#/R-RNO-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Rattus norvegicus 57287 R-RNO-1482646 https://reactome.org/PathwayBrowser/#/R-RNO-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Rattus norvegicus 57287 R-RNO-1482667 https://reactome.org/PathwayBrowser/#/R-RNO-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Rattus norvegicus 57287 R-RNO-1482689 https://reactome.org/PathwayBrowser/#/R-RNO-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Rattus norvegicus 57287 R-RNO-1482691 https://reactome.org/PathwayBrowser/#/R-RNO-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Rattus norvegicus 57287 R-RNO-1482695 https://reactome.org/PathwayBrowser/#/R-RNO-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Rattus norvegicus 57287 R-RNO-1482775 https://reactome.org/PathwayBrowser/#/R-RNO-1482775 MLCL is acylated to CL by HADH (IM) IEA Rattus norvegicus 57287 R-RNO-1482861 https://reactome.org/PathwayBrowser/#/R-RNO-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Rattus norvegicus 57287 R-RNO-1482867 https://reactome.org/PathwayBrowser/#/R-RNO-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Rattus norvegicus 57287 R-RNO-1482889 https://reactome.org/PathwayBrowser/#/R-RNO-1482889 DAG is acylated to TAG by DGAT1/2 IEA Rattus norvegicus 57287 R-RNO-1483002 https://reactome.org/PathwayBrowser/#/R-RNO-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Rattus norvegicus 57287 R-RNO-158832 https://reactome.org/PathwayBrowser/#/R-RNO-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Rattus norvegicus 57287 R-RNO-159425 https://reactome.org/PathwayBrowser/#/R-RNO-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 57287 R-RNO-159431 https://reactome.org/PathwayBrowser/#/R-RNO-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Rattus norvegicus 57287 R-RNO-159443 https://reactome.org/PathwayBrowser/#/R-RNO-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 57287 R-RNO-159566 https://reactome.org/PathwayBrowser/#/R-RNO-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Rattus norvegicus 57287 R-RNO-159567 https://reactome.org/PathwayBrowser/#/R-RNO-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Rattus norvegicus 57287 R-RNO-159574 https://reactome.org/PathwayBrowser/#/R-RNO-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Rattus norvegicus 57287 R-RNO-162683 https://reactome.org/PathwayBrowser/#/R-RNO-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Rattus norvegicus 57287 R-RNO-1678660 https://reactome.org/PathwayBrowser/#/R-RNO-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Rattus norvegicus 57287 R-RNO-174959 https://reactome.org/PathwayBrowser/#/R-RNO-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Rattus norvegicus 57287 R-RNO-177157 https://reactome.org/PathwayBrowser/#/R-RNO-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 57287 R-RNO-189442 https://reactome.org/PathwayBrowser/#/R-RNO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Rattus norvegicus 57287 R-RNO-191323 https://reactome.org/PathwayBrowser/#/R-RNO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Rattus norvegicus 57287 R-RNO-191352 https://reactome.org/PathwayBrowser/#/R-RNO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Rattus norvegicus 57287 R-RNO-192137 https://reactome.org/PathwayBrowser/#/R-RNO-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 57287 R-RNO-192312 https://reactome.org/PathwayBrowser/#/R-RNO-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Rattus norvegicus 57287 R-RNO-192341 https://reactome.org/PathwayBrowser/#/R-RNO-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Rattus norvegicus 57287 R-RNO-193385 https://reactome.org/PathwayBrowser/#/R-RNO-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Rattus norvegicus 57287 R-RNO-193401 https://reactome.org/PathwayBrowser/#/R-RNO-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 57287 R-RNO-193407 https://reactome.org/PathwayBrowser/#/R-RNO-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 57287 R-RNO-193424 https://reactome.org/PathwayBrowser/#/R-RNO-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 57287 R-RNO-193491 https://reactome.org/PathwayBrowser/#/R-RNO-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Rattus norvegicus 57287 R-RNO-193533 https://reactome.org/PathwayBrowser/#/R-RNO-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Rattus norvegicus 57287 R-RNO-193711 https://reactome.org/PathwayBrowser/#/R-RNO-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 57287 R-RNO-193727 https://reactome.org/PathwayBrowser/#/R-RNO-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 57287 R-RNO-193743 https://reactome.org/PathwayBrowser/#/R-RNO-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 57287 R-RNO-193766 https://reactome.org/PathwayBrowser/#/R-RNO-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 57287 R-RNO-196773 https://reactome.org/PathwayBrowser/#/R-RNO-196773 COASY phosphorylates DP-CoA IEA Rattus norvegicus 57287 R-RNO-196857 https://reactome.org/PathwayBrowser/#/R-RNO-196857 PANK2 phosphorylates PanK IEA Rattus norvegicus 57287 R-RNO-199202 https://reactome.org/PathwayBrowser/#/R-RNO-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Rattus norvegicus 57287 R-RNO-199216 https://reactome.org/PathwayBrowser/#/R-RNO-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Rattus norvegicus 57287 R-RNO-200406 https://reactome.org/PathwayBrowser/#/R-RNO-200406 CPT1A,B transfers PALM to CAR IEA Rattus norvegicus 57287 R-RNO-200410 https://reactome.org/PathwayBrowser/#/R-RNO-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Rattus norvegicus 57287 R-RNO-201035 https://reactome.org/PathwayBrowser/#/R-RNO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Rattus norvegicus 57287 R-RNO-2046083 https://reactome.org/PathwayBrowser/#/R-RNO-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Rattus norvegicus 57287 R-RNO-2046085 https://reactome.org/PathwayBrowser/#/R-RNO-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Rattus norvegicus 57287 R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus 57287 R-RNO-2046090 https://reactome.org/PathwayBrowser/#/R-RNO-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 57287 R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus 57287 R-RNO-2046095 https://reactome.org/PathwayBrowser/#/R-RNO-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Rattus norvegicus 57287 R-RNO-2046098 https://reactome.org/PathwayBrowser/#/R-RNO-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Rattus norvegicus 57287 R-RNO-2046100 https://reactome.org/PathwayBrowser/#/R-RNO-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Rattus norvegicus 57287 R-RNO-2066779 https://reactome.org/PathwayBrowser/#/R-RNO-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Rattus norvegicus 57287 R-RNO-2066781 https://reactome.org/PathwayBrowser/#/R-RNO-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Rattus norvegicus 57287 R-RNO-2066788 https://reactome.org/PathwayBrowser/#/R-RNO-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Rattus norvegicus 57287 R-RNO-2090085 https://reactome.org/PathwayBrowser/#/R-RNO-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Rattus norvegicus 57287 R-RNO-209792 https://reactome.org/PathwayBrowser/#/R-RNO-209792 N-acetylation of serotonin IEA Rattus norvegicus 57287 R-RNO-2465919 https://reactome.org/PathwayBrowser/#/R-RNO-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Rattus norvegicus 57287 R-RNO-2468039 https://reactome.org/PathwayBrowser/#/R-RNO-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Rattus norvegicus 57287 R-RNO-2473152 https://reactome.org/PathwayBrowser/#/R-RNO-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Rattus norvegicus 57287 R-RNO-2534087 https://reactome.org/PathwayBrowser/#/R-RNO-2534087 NMT1/2 transfer MYS to GNAT1 IEA Rattus norvegicus 57287 R-RNO-2545203 https://reactome.org/PathwayBrowser/#/R-RNO-2545203 Deacetylation of cleaved cohesin IEA Rattus norvegicus 57287 R-RNO-2545253 https://reactome.org/PathwayBrowser/#/R-RNO-2545253 Deacetylation of cohesin IEA Rattus norvegicus 57287 R-RNO-264622 https://reactome.org/PathwayBrowser/#/R-RNO-264622 Cho is acetylated to AcCho by CHAT IEA Rattus norvegicus 57287 R-RNO-3318413 https://reactome.org/PathwayBrowser/#/R-RNO-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Rattus norvegicus 57287 R-RNO-3318415 https://reactome.org/PathwayBrowser/#/R-RNO-3318415 ATF2 acetylates histone H2B, H4 IEA Rattus norvegicus 57287 R-RNO-3318486 https://reactome.org/PathwayBrowser/#/R-RNO-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Rattus norvegicus 57287 R-RNO-3321805 https://reactome.org/PathwayBrowser/#/R-RNO-3321805 NSL acetylates histone H4 IEA Rattus norvegicus 57287 R-RNO-3321883 https://reactome.org/PathwayBrowser/#/R-RNO-3321883 MSL acetylates histone H4 IEA Rattus norvegicus 57287 R-RNO-3371554 https://reactome.org/PathwayBrowser/#/R-RNO-3371554 HSF1 acetylation at Lys80 IEA Rattus norvegicus 57287 R-RNO-351207 https://reactome.org/PathwayBrowser/#/R-RNO-351207 Spermine => N-acetylated spermine IEA Rattus norvegicus 57287 R-RNO-351208 https://reactome.org/PathwayBrowser/#/R-RNO-351208 Spermidine => N-acetylated spermidine IEA Rattus norvegicus 57287 R-RNO-3662318 https://reactome.org/PathwayBrowser/#/R-RNO-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Rattus norvegicus 57287 R-RNO-389622 https://reactome.org/PathwayBrowser/#/R-RNO-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 57287 R-RNO-389632 https://reactome.org/PathwayBrowser/#/R-RNO-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 57287 R-RNO-390224 https://reactome.org/PathwayBrowser/#/R-RNO-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA IEA Rattus norvegicus 57287 R-RNO-390250 https://reactome.org/PathwayBrowser/#/R-RNO-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Rattus norvegicus 57287 R-RNO-390281 https://reactome.org/PathwayBrowser/#/R-RNO-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Rattus norvegicus 57287 R-RNO-390284 https://reactome.org/PathwayBrowser/#/R-RNO-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Rattus norvegicus 57287 R-RNO-390291 https://reactome.org/PathwayBrowser/#/R-RNO-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Rattus norvegicus 57287 R-RNO-390304 https://reactome.org/PathwayBrowser/#/R-RNO-390304 acetyl-CoA + H2O => acetate + CoASH IEA Rattus norvegicus 57287 R-RNO-390425 https://reactome.org/PathwayBrowser/#/R-RNO-390425 FAR1 reduces PalmCoA to HXOL IEA Rattus norvegicus 57287 R-RNO-390438 https://reactome.org/PathwayBrowser/#/R-RNO-390438 FAR2 reduces PalmCoA to HXOL IEA Rattus norvegicus 57287 R-RNO-428127 https://reactome.org/PathwayBrowser/#/R-RNO-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Rattus norvegicus 57287 R-RNO-428185 https://reactome.org/PathwayBrowser/#/R-RNO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Rattus norvegicus 57287 R-RNO-434382 https://reactome.org/PathwayBrowser/#/R-RNO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Rattus norvegicus 57287 R-RNO-449734 https://reactome.org/PathwayBrowser/#/R-RNO-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Rattus norvegicus 57287 R-RNO-449911 https://reactome.org/PathwayBrowser/#/R-RNO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Rattus norvegicus 57287 R-RNO-5250938 https://reactome.org/PathwayBrowser/#/R-RNO-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Rattus norvegicus 57287 R-RNO-5358343 https://reactome.org/PathwayBrowser/#/R-RNO-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Rattus norvegicus 57287 R-RNO-548800 https://reactome.org/PathwayBrowser/#/R-RNO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Rattus norvegicus 57287 R-RNO-548814 https://reactome.org/PathwayBrowser/#/R-RNO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Rattus norvegicus 57287 R-RNO-548815 https://reactome.org/PathwayBrowser/#/R-RNO-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Rattus norvegicus 57287 R-RNO-548843 https://reactome.org/PathwayBrowser/#/R-RNO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Rattus norvegicus 57287 R-RNO-549112 https://reactome.org/PathwayBrowser/#/R-RNO-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Rattus norvegicus 57287 R-RNO-549192 https://reactome.org/PathwayBrowser/#/R-RNO-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Rattus norvegicus 57287 R-RNO-5618328 https://reactome.org/PathwayBrowser/#/R-RNO-5618328 ATAT acetylates microtubules IEA Rattus norvegicus 57287 R-RNO-5628871 https://reactome.org/PathwayBrowser/#/R-RNO-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Rattus norvegicus 57287 R-RNO-5682044 https://reactome.org/PathwayBrowser/#/R-RNO-5682044 KAT5 acetylates ATM at DNA DSBs IEA Rattus norvegicus 57287 R-RNO-5682084 https://reactome.org/PathwayBrowser/#/R-RNO-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Rattus norvegicus 57287 R-RNO-5686304 https://reactome.org/PathwayBrowser/#/R-RNO-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Rattus norvegicus 57287 R-RNO-5690042 https://reactome.org/PathwayBrowser/#/R-RNO-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 57287 R-RNO-5690043 https://reactome.org/PathwayBrowser/#/R-RNO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 57287 R-RNO-5690046 https://reactome.org/PathwayBrowser/#/R-RNO-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Rattus norvegicus 57287 R-RNO-5690066 https://reactome.org/PathwayBrowser/#/R-RNO-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 57287 R-RNO-5694494 https://reactome.org/PathwayBrowser/#/R-RNO-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Rattus norvegicus 57287 R-RNO-5695957 https://reactome.org/PathwayBrowser/#/R-RNO-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Rattus norvegicus 57287 R-RNO-5696004 https://reactome.org/PathwayBrowser/#/R-RNO-5696004 ACSF2 ligates CoA-SH to MCFA IEA Rattus norvegicus 57287 R-RNO-5696007 https://reactome.org/PathwayBrowser/#/R-RNO-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Rattus norvegicus 57287 R-RNO-5696424 https://reactome.org/PathwayBrowser/#/R-RNO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Rattus norvegicus 57287 R-RNO-5696448 https://reactome.org/PathwayBrowser/#/R-RNO-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Rattus norvegicus 57287 R-RNO-6792712 https://reactome.org/PathwayBrowser/#/R-RNO-6792712 KAT5 acetylates ATM at shortened telomeres IEA Rattus norvegicus 57287 R-RNO-6800334 https://reactome.org/PathwayBrowser/#/R-RNO-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Rattus norvegicus 57287 R-RNO-6805638 https://reactome.org/PathwayBrowser/#/R-RNO-6805638 KAT6A acetylates TP53 IEA Rattus norvegicus 57287 R-RNO-6811508 https://reactome.org/PathwayBrowser/#/R-RNO-6811508 ING2-bound EP300 acetylates TP53 IEA Rattus norvegicus 57287 R-RNO-70542 https://reactome.org/PathwayBrowser/#/R-RNO-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Rattus norvegicus 57287 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 57287 R-RNO-70844 https://reactome.org/PathwayBrowser/#/R-RNO-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Rattus norvegicus 57287 R-RNO-70881 https://reactome.org/PathwayBrowser/#/R-RNO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Rattus norvegicus 57287 R-RNO-70893 https://reactome.org/PathwayBrowser/#/R-RNO-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 57287 R-RNO-70975 https://reactome.org/PathwayBrowser/#/R-RNO-70975 CS acetylates OA to citrate IEA Rattus norvegicus 57287 R-RNO-70997 https://reactome.org/PathwayBrowser/#/R-RNO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Rattus norvegicus 57287 R-RNO-71037 https://reactome.org/PathwayBrowser/#/R-RNO-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 57287 R-RNO-71735 https://reactome.org/PathwayBrowser/#/R-RNO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Rattus norvegicus 57287 R-RNO-71775 https://reactome.org/PathwayBrowser/#/R-RNO-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Rattus norvegicus 57287 R-RNO-73916 https://reactome.org/PathwayBrowser/#/R-RNO-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Rattus norvegicus 57287 R-RNO-73918 https://reactome.org/PathwayBrowser/#/R-RNO-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Rattus norvegicus 57287 R-RNO-74181 https://reactome.org/PathwayBrowser/#/R-RNO-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Rattus norvegicus 57287 R-RNO-75848 https://reactome.org/PathwayBrowser/#/R-RNO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Rattus norvegicus 57287 R-RNO-75872 https://reactome.org/PathwayBrowser/#/R-RNO-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Rattus norvegicus 57287 R-RNO-75879 https://reactome.org/PathwayBrowser/#/R-RNO-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Rattus norvegicus 57287 R-RNO-75885 https://reactome.org/PathwayBrowser/#/R-RNO-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Rattus norvegicus 57287 R-RNO-75886 https://reactome.org/PathwayBrowser/#/R-RNO-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Rattus norvegicus 57287 R-RNO-75900 https://reactome.org/PathwayBrowser/#/R-RNO-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Rattus norvegicus 57287 R-RNO-77271 https://reactome.org/PathwayBrowser/#/R-RNO-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Rattus norvegicus 57287 R-RNO-77304 https://reactome.org/PathwayBrowser/#/R-RNO-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Rattus norvegicus 57287 R-RNO-77309 https://reactome.org/PathwayBrowser/#/R-RNO-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Rattus norvegicus 57287 R-RNO-77321 https://reactome.org/PathwayBrowser/#/R-RNO-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Rattus norvegicus 57287 R-RNO-77329 https://reactome.org/PathwayBrowser/#/R-RNO-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Rattus norvegicus 57287 R-RNO-77340 https://reactome.org/PathwayBrowser/#/R-RNO-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Rattus norvegicus 57287 R-RNO-8848215 https://reactome.org/PathwayBrowser/#/R-RNO-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Rattus norvegicus 57287 R-RNO-8848580 https://reactome.org/PathwayBrowser/#/R-RNO-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Rattus norvegicus 57287 R-RNO-8848582 https://reactome.org/PathwayBrowser/#/R-RNO-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Rattus norvegicus 57287 R-RNO-8848585 https://reactome.org/PathwayBrowser/#/R-RNO-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Rattus norvegicus 57287 R-RNO-8849345 https://reactome.org/PathwayBrowser/#/R-RNO-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Rattus norvegicus 57287 R-RNO-8874745 https://reactome.org/PathwayBrowser/#/R-RNO-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Rattus norvegicus 57287 R-RNO-8875071 https://reactome.org/PathwayBrowser/#/R-RNO-8875071 ACSS3 ligates CoA to CH3COO- IEA Rattus norvegicus 57287 R-RNO-8876696 https://reactome.org/PathwayBrowser/#/R-RNO-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Rattus norvegicus 57287 R-RNO-8933547 https://reactome.org/PathwayBrowser/#/R-RNO-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Rattus norvegicus 57287 R-RNO-8951966 https://reactome.org/PathwayBrowser/#/R-RNO-8951966 EP300 acetylates RUNX3 IEA Rattus norvegicus 57287 R-RNO-8954468 https://reactome.org/PathwayBrowser/#/R-RNO-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Rattus norvegicus 57287 R-RNO-9021072 https://reactome.org/PathwayBrowser/#/R-RNO-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Rattus norvegicus 57287 R-RNO-9620515 https://reactome.org/PathwayBrowser/#/R-RNO-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Rattus norvegicus 57287 R-RNO-9647982 https://reactome.org/PathwayBrowser/#/R-RNO-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Rattus norvegicus 57287 R-RNO-9701531 https://reactome.org/PathwayBrowser/#/R-RNO-9701531 p-Y705,S727 STAT3 is acetylated IEA Rattus norvegicus 57287 R-RNO-9734535 https://reactome.org/PathwayBrowser/#/R-RNO-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Rattus norvegicus 57287 R-RNO-9749971 https://reactome.org/PathwayBrowser/#/R-RNO-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Rattus norvegicus 57287 R-RNO-9750001 https://reactome.org/PathwayBrowser/#/R-RNO-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Rattus norvegicus 57287 R-RNO-9753676 https://reactome.org/PathwayBrowser/#/R-RNO-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Rattus norvegicus 57287 R-RNO-9760081 https://reactome.org/PathwayBrowser/#/R-RNO-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Rattus norvegicus 57287 R-RNO-9825747 https://reactome.org/PathwayBrowser/#/R-RNO-9825747 CREBBP acetylates HINT1 dimer IEA Rattus norvegicus 57287 R-RNO-9837333 https://reactome.org/PathwayBrowser/#/R-RNO-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Rattus norvegicus 57287 R-RNO-9837337 https://reactome.org/PathwayBrowser/#/R-RNO-9837337 DCAKD phosphorylates DP-CoA IEA Rattus norvegicus 57287 R-RNO-9853512 https://reactome.org/PathwayBrowser/#/R-RNO-9853512 DLST transfers succinyl to CoA IEA Rattus norvegicus 57287 R-RNO-9854415 https://reactome.org/PathwayBrowser/#/R-RNO-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Rattus norvegicus 57287 R-RNO-9861667 https://reactome.org/PathwayBrowser/#/R-RNO-9861667 DLAT trimer transfers acetyl to CoA IEA Rattus norvegicus 57287 R-SCE-1482533 https://reactome.org/PathwayBrowser/#/R-SCE-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Saccharomyces cerevisiae 57287 R-SCE-1482539 https://reactome.org/PathwayBrowser/#/R-SCE-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Saccharomyces cerevisiae 57287 R-SCE-1482546 https://reactome.org/PathwayBrowser/#/R-SCE-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Saccharomyces cerevisiae 57287 R-SCE-1482547 https://reactome.org/PathwayBrowser/#/R-SCE-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Saccharomyces cerevisiae 57287 R-SCE-1482598 https://reactome.org/PathwayBrowser/#/R-SCE-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Saccharomyces cerevisiae 57287 R-SCE-1482626 https://reactome.org/PathwayBrowser/#/R-SCE-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Saccharomyces cerevisiae 57287 R-SCE-1482635 https://reactome.org/PathwayBrowser/#/R-SCE-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Saccharomyces cerevisiae 57287 R-SCE-1482636 https://reactome.org/PathwayBrowser/#/R-SCE-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Saccharomyces cerevisiae 57287 R-SCE-1482646 https://reactome.org/PathwayBrowser/#/R-SCE-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Saccharomyces cerevisiae 57287 R-SCE-1482667 https://reactome.org/PathwayBrowser/#/R-SCE-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Saccharomyces cerevisiae 57287 R-SCE-1482689 https://reactome.org/PathwayBrowser/#/R-SCE-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Saccharomyces cerevisiae 57287 R-SCE-1482691 https://reactome.org/PathwayBrowser/#/R-SCE-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Saccharomyces cerevisiae 57287 R-SCE-1482861 https://reactome.org/PathwayBrowser/#/R-SCE-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Saccharomyces cerevisiae 57287 R-SCE-1482867 https://reactome.org/PathwayBrowser/#/R-SCE-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Saccharomyces cerevisiae 57287 R-SCE-1482889 https://reactome.org/PathwayBrowser/#/R-SCE-1482889 DAG is acylated to TAG by DGAT1/2 IEA Saccharomyces cerevisiae 57287 R-SCE-159425 https://reactome.org/PathwayBrowser/#/R-SCE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 57287 R-SCE-162683 https://reactome.org/PathwayBrowser/#/R-SCE-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Saccharomyces cerevisiae 57287 R-SCE-189442 https://reactome.org/PathwayBrowser/#/R-SCE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Saccharomyces cerevisiae 57287 R-SCE-191323 https://reactome.org/PathwayBrowser/#/R-SCE-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-191352 https://reactome.org/PathwayBrowser/#/R-SCE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Saccharomyces cerevisiae 57287 R-SCE-192137 https://reactome.org/PathwayBrowser/#/R-SCE-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 57287 R-SCE-193385 https://reactome.org/PathwayBrowser/#/R-SCE-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Saccharomyces cerevisiae 57287 R-SCE-193401 https://reactome.org/PathwayBrowser/#/R-SCE-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 57287 R-SCE-193407 https://reactome.org/PathwayBrowser/#/R-SCE-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 57287 R-SCE-193424 https://reactome.org/PathwayBrowser/#/R-SCE-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 57287 R-SCE-193711 https://reactome.org/PathwayBrowser/#/R-SCE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 57287 R-SCE-193727 https://reactome.org/PathwayBrowser/#/R-SCE-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 57287 R-SCE-193743 https://reactome.org/PathwayBrowser/#/R-SCE-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 57287 R-SCE-193766 https://reactome.org/PathwayBrowser/#/R-SCE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 57287 R-SCE-196773 https://reactome.org/PathwayBrowser/#/R-SCE-196773 COASY phosphorylates DP-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-199216 https://reactome.org/PathwayBrowser/#/R-SCE-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Saccharomyces cerevisiae 57287 R-SCE-201035 https://reactome.org/PathwayBrowser/#/R-SCE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-2046088 https://reactome.org/PathwayBrowser/#/R-SCE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-2046094 https://reactome.org/PathwayBrowser/#/R-SCE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-2066779 https://reactome.org/PathwayBrowser/#/R-SCE-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Saccharomyces cerevisiae 57287 R-SCE-2066788 https://reactome.org/PathwayBrowser/#/R-SCE-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Saccharomyces cerevisiae 57287 R-SCE-209792 https://reactome.org/PathwayBrowser/#/R-SCE-209792 N-acetylation of serotonin IEA Saccharomyces cerevisiae 57287 R-SCE-2468039 https://reactome.org/PathwayBrowser/#/R-SCE-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Saccharomyces cerevisiae 57287 R-SCE-2473152 https://reactome.org/PathwayBrowser/#/R-SCE-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Saccharomyces cerevisiae 57287 R-SCE-2534087 https://reactome.org/PathwayBrowser/#/R-SCE-2534087 NMT1/2 transfer MYS to GNAT1 IEA Saccharomyces cerevisiae 57287 R-SCE-2545253 https://reactome.org/PathwayBrowser/#/R-SCE-2545253 Deacetylation of cohesin IEA Saccharomyces cerevisiae 57287 R-SCE-3318415 https://reactome.org/PathwayBrowser/#/R-SCE-3318415 ATF2 acetylates histone H2B, H4 IEA Saccharomyces cerevisiae 57287 R-SCE-351207 https://reactome.org/PathwayBrowser/#/R-SCE-351207 Spermine => N-acetylated spermine IEA Saccharomyces cerevisiae 57287 R-SCE-351208 https://reactome.org/PathwayBrowser/#/R-SCE-351208 Spermidine => N-acetylated spermidine IEA Saccharomyces cerevisiae 57287 R-SCE-3662318 https://reactome.org/PathwayBrowser/#/R-SCE-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Saccharomyces cerevisiae 57287 R-SCE-389622 https://reactome.org/PathwayBrowser/#/R-SCE-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 57287 R-SCE-389632 https://reactome.org/PathwayBrowser/#/R-SCE-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 57287 R-SCE-390250 https://reactome.org/PathwayBrowser/#/R-SCE-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-390304 https://reactome.org/PathwayBrowser/#/R-SCE-390304 acetyl-CoA + H2O => acetate + CoASH IEA Saccharomyces cerevisiae 57287 R-SCE-428185 https://reactome.org/PathwayBrowser/#/R-SCE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Saccharomyces cerevisiae 57287 R-SCE-434382 https://reactome.org/PathwayBrowser/#/R-SCE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Saccharomyces cerevisiae 57287 R-SCE-449734 https://reactome.org/PathwayBrowser/#/R-SCE-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Saccharomyces cerevisiae 57287 R-SCE-449911 https://reactome.org/PathwayBrowser/#/R-SCE-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Saccharomyces cerevisiae 57287 R-SCE-548800 https://reactome.org/PathwayBrowser/#/R-SCE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-548814 https://reactome.org/PathwayBrowser/#/R-SCE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-548843 https://reactome.org/PathwayBrowser/#/R-SCE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-549192 https://reactome.org/PathwayBrowser/#/R-SCE-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Saccharomyces cerevisiae 57287 R-SCE-5682044 https://reactome.org/PathwayBrowser/#/R-SCE-5682044 KAT5 acetylates ATM at DNA DSBs IEA Saccharomyces cerevisiae 57287 R-SCE-5690042 https://reactome.org/PathwayBrowser/#/R-SCE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-5696424 https://reactome.org/PathwayBrowser/#/R-SCE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Saccharomyces cerevisiae 57287 R-SCE-5696448 https://reactome.org/PathwayBrowser/#/R-SCE-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Saccharomyces cerevisiae 57287 R-SCE-6792712 https://reactome.org/PathwayBrowser/#/R-SCE-6792712 KAT5 acetylates ATM at shortened telomeres IEA Saccharomyces cerevisiae 57287 R-SCE-6800334 https://reactome.org/PathwayBrowser/#/R-SCE-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Saccharomyces cerevisiae 57287 R-SCE-70542 https://reactome.org/PathwayBrowser/#/R-SCE-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Saccharomyces cerevisiae 57287 R-SCE-70881 https://reactome.org/PathwayBrowser/#/R-SCE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Saccharomyces cerevisiae 57287 R-SCE-70975 https://reactome.org/PathwayBrowser/#/R-SCE-70975 CS acetylates OA to citrate IEA Saccharomyces cerevisiae 57287 R-SCE-70997 https://reactome.org/PathwayBrowser/#/R-SCE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-71735 https://reactome.org/PathwayBrowser/#/R-SCE-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Saccharomyces cerevisiae 57287 R-SCE-73918 https://reactome.org/PathwayBrowser/#/R-SCE-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Saccharomyces cerevisiae 57287 R-SCE-75885 https://reactome.org/PathwayBrowser/#/R-SCE-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Saccharomyces cerevisiae 57287 R-SCE-8848215 https://reactome.org/PathwayBrowser/#/R-SCE-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-8848580 https://reactome.org/PathwayBrowser/#/R-SCE-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Saccharomyces cerevisiae 57287 R-SCE-8848582 https://reactome.org/PathwayBrowser/#/R-SCE-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Saccharomyces cerevisiae 57287 R-SCE-8848585 https://reactome.org/PathwayBrowser/#/R-SCE-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Saccharomyces cerevisiae 57287 R-SCE-8849345 https://reactome.org/PathwayBrowser/#/R-SCE-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Saccharomyces cerevisiae 57287 R-SCE-8933547 https://reactome.org/PathwayBrowser/#/R-SCE-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Saccharomyces cerevisiae 57287 R-SCE-9734535 https://reactome.org/PathwayBrowser/#/R-SCE-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-9837337 https://reactome.org/PathwayBrowser/#/R-SCE-9837337 DCAKD phosphorylates DP-CoA IEA Saccharomyces cerevisiae 57287 R-SCE-9853512 https://reactome.org/PathwayBrowser/#/R-SCE-9853512 DLST transfers succinyl to CoA IEA Saccharomyces cerevisiae 57287 R-SCE-9861667 https://reactome.org/PathwayBrowser/#/R-SCE-9861667 DLAT trimer transfers acetyl to CoA IEA Saccharomyces cerevisiae 57287 R-SPO-1482533 https://reactome.org/PathwayBrowser/#/R-SPO-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Schizosaccharomyces pombe 57287 R-SPO-1482539 https://reactome.org/PathwayBrowser/#/R-SPO-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Schizosaccharomyces pombe 57287 R-SPO-1482546 https://reactome.org/PathwayBrowser/#/R-SPO-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Schizosaccharomyces pombe 57287 R-SPO-1482547 https://reactome.org/PathwayBrowser/#/R-SPO-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Schizosaccharomyces pombe 57287 R-SPO-1482598 https://reactome.org/PathwayBrowser/#/R-SPO-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Schizosaccharomyces pombe 57287 R-SPO-1482626 https://reactome.org/PathwayBrowser/#/R-SPO-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Schizosaccharomyces pombe 57287 R-SPO-1482635 https://reactome.org/PathwayBrowser/#/R-SPO-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Schizosaccharomyces pombe 57287 R-SPO-1482636 https://reactome.org/PathwayBrowser/#/R-SPO-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Schizosaccharomyces pombe 57287 R-SPO-1482646 https://reactome.org/PathwayBrowser/#/R-SPO-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Schizosaccharomyces pombe 57287 R-SPO-1482667 https://reactome.org/PathwayBrowser/#/R-SPO-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Schizosaccharomyces pombe 57287 R-SPO-1482689 https://reactome.org/PathwayBrowser/#/R-SPO-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Schizosaccharomyces pombe 57287 R-SPO-1482691 https://reactome.org/PathwayBrowser/#/R-SPO-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Schizosaccharomyces pombe 57287 R-SPO-1482861 https://reactome.org/PathwayBrowser/#/R-SPO-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Schizosaccharomyces pombe 57287 R-SPO-1482867 https://reactome.org/PathwayBrowser/#/R-SPO-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Schizosaccharomyces pombe 57287 R-SPO-1482889 https://reactome.org/PathwayBrowser/#/R-SPO-1482889 DAG is acylated to TAG by DGAT1/2 IEA Schizosaccharomyces pombe 57287 R-SPO-162683 https://reactome.org/PathwayBrowser/#/R-SPO-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Schizosaccharomyces pombe 57287 R-SPO-189442 https://reactome.org/PathwayBrowser/#/R-SPO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Schizosaccharomyces pombe 57287 R-SPO-191323 https://reactome.org/PathwayBrowser/#/R-SPO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-191352 https://reactome.org/PathwayBrowser/#/R-SPO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Schizosaccharomyces pombe 57287 R-SPO-196773 https://reactome.org/PathwayBrowser/#/R-SPO-196773 COASY phosphorylates DP-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-199216 https://reactome.org/PathwayBrowser/#/R-SPO-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Schizosaccharomyces pombe 57287 R-SPO-201035 https://reactome.org/PathwayBrowser/#/R-SPO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-2046088 https://reactome.org/PathwayBrowser/#/R-SPO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-2046094 https://reactome.org/PathwayBrowser/#/R-SPO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-209792 https://reactome.org/PathwayBrowser/#/R-SPO-209792 N-acetylation of serotonin IEA Schizosaccharomyces pombe 57287 R-SPO-2534087 https://reactome.org/PathwayBrowser/#/R-SPO-2534087 NMT1/2 transfer MYS to GNAT1 IEA Schizosaccharomyces pombe 57287 R-SPO-3318413 https://reactome.org/PathwayBrowser/#/R-SPO-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Schizosaccharomyces pombe 57287 R-SPO-3318415 https://reactome.org/PathwayBrowser/#/R-SPO-3318415 ATF2 acetylates histone H2B, H4 IEA Schizosaccharomyces pombe 57287 R-SPO-3318486 https://reactome.org/PathwayBrowser/#/R-SPO-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Schizosaccharomyces pombe 57287 R-SPO-351207 https://reactome.org/PathwayBrowser/#/R-SPO-351207 Spermine => N-acetylated spermine IEA Schizosaccharomyces pombe 57287 R-SPO-351208 https://reactome.org/PathwayBrowser/#/R-SPO-351208 Spermidine => N-acetylated spermidine IEA Schizosaccharomyces pombe 57287 R-SPO-3662318 https://reactome.org/PathwayBrowser/#/R-SPO-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Schizosaccharomyces pombe 57287 R-SPO-428185 https://reactome.org/PathwayBrowser/#/R-SPO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Schizosaccharomyces pombe 57287 R-SPO-434382 https://reactome.org/PathwayBrowser/#/R-SPO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Schizosaccharomyces pombe 57287 R-SPO-449734 https://reactome.org/PathwayBrowser/#/R-SPO-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Schizosaccharomyces pombe 57287 R-SPO-449911 https://reactome.org/PathwayBrowser/#/R-SPO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Schizosaccharomyces pombe 57287 R-SPO-548800 https://reactome.org/PathwayBrowser/#/R-SPO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-548814 https://reactome.org/PathwayBrowser/#/R-SPO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-548843 https://reactome.org/PathwayBrowser/#/R-SPO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-549192 https://reactome.org/PathwayBrowser/#/R-SPO-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Schizosaccharomyces pombe 57287 R-SPO-5682044 https://reactome.org/PathwayBrowser/#/R-SPO-5682044 KAT5 acetylates ATM at DNA DSBs IEA Schizosaccharomyces pombe 57287 R-SPO-5690043 https://reactome.org/PathwayBrowser/#/R-SPO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-5696424 https://reactome.org/PathwayBrowser/#/R-SPO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Schizosaccharomyces pombe 57287 R-SPO-5696448 https://reactome.org/PathwayBrowser/#/R-SPO-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Schizosaccharomyces pombe 57287 R-SPO-6792712 https://reactome.org/PathwayBrowser/#/R-SPO-6792712 KAT5 acetylates ATM at shortened telomeres IEA Schizosaccharomyces pombe 57287 R-SPO-6800334 https://reactome.org/PathwayBrowser/#/R-SPO-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Schizosaccharomyces pombe 57287 R-SPO-70542 https://reactome.org/PathwayBrowser/#/R-SPO-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Schizosaccharomyces pombe 57287 R-SPO-70881 https://reactome.org/PathwayBrowser/#/R-SPO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Schizosaccharomyces pombe 57287 R-SPO-70975 https://reactome.org/PathwayBrowser/#/R-SPO-70975 CS acetylates OA to citrate IEA Schizosaccharomyces pombe 57287 R-SPO-70997 https://reactome.org/PathwayBrowser/#/R-SPO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-71735 https://reactome.org/PathwayBrowser/#/R-SPO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Schizosaccharomyces pombe 57287 R-SPO-73918 https://reactome.org/PathwayBrowser/#/R-SPO-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Schizosaccharomyces pombe 57287 R-SPO-75848 https://reactome.org/PathwayBrowser/#/R-SPO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-75885 https://reactome.org/PathwayBrowser/#/R-SPO-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Schizosaccharomyces pombe 57287 R-SPO-8848215 https://reactome.org/PathwayBrowser/#/R-SPO-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-8848580 https://reactome.org/PathwayBrowser/#/R-SPO-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Schizosaccharomyces pombe 57287 R-SPO-8848582 https://reactome.org/PathwayBrowser/#/R-SPO-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Schizosaccharomyces pombe 57287 R-SPO-8848585 https://reactome.org/PathwayBrowser/#/R-SPO-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Schizosaccharomyces pombe 57287 R-SPO-8933547 https://reactome.org/PathwayBrowser/#/R-SPO-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Schizosaccharomyces pombe 57287 R-SPO-9837337 https://reactome.org/PathwayBrowser/#/R-SPO-9837337 DCAKD phosphorylates DP-CoA IEA Schizosaccharomyces pombe 57287 R-SPO-9853512 https://reactome.org/PathwayBrowser/#/R-SPO-9853512 DLST transfers succinyl to CoA IEA Schizosaccharomyces pombe 57287 R-SPO-9861667 https://reactome.org/PathwayBrowser/#/R-SPO-9861667 DLAT trimer transfers acetyl to CoA IEA Schizosaccharomyces pombe 57287 R-SSC-1482533 https://reactome.org/PathwayBrowser/#/R-SSC-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Sus scrofa 57287 R-SSC-1482539 https://reactome.org/PathwayBrowser/#/R-SSC-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa 57287 R-SSC-1482546 https://reactome.org/PathwayBrowser/#/R-SSC-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Sus scrofa 57287 R-SSC-1482547 https://reactome.org/PathwayBrowser/#/R-SSC-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Sus scrofa 57287 R-SSC-1482548 https://reactome.org/PathwayBrowser/#/R-SSC-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Sus scrofa 57287 R-SSC-1482598 https://reactome.org/PathwayBrowser/#/R-SSC-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Sus scrofa 57287 R-SSC-1482626 https://reactome.org/PathwayBrowser/#/R-SSC-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Sus scrofa 57287 R-SSC-1482635 https://reactome.org/PathwayBrowser/#/R-SSC-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa 57287 R-SSC-1482636 https://reactome.org/PathwayBrowser/#/R-SSC-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa 57287 R-SSC-1482646 https://reactome.org/PathwayBrowser/#/R-SSC-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Sus scrofa 57287 R-SSC-1482667 https://reactome.org/PathwayBrowser/#/R-SSC-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Sus scrofa 57287 R-SSC-1482689 https://reactome.org/PathwayBrowser/#/R-SSC-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Sus scrofa 57287 R-SSC-1482691 https://reactome.org/PathwayBrowser/#/R-SSC-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa 57287 R-SSC-1482695 https://reactome.org/PathwayBrowser/#/R-SSC-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Sus scrofa 57287 R-SSC-1482775 https://reactome.org/PathwayBrowser/#/R-SSC-1482775 MLCL is acylated to CL by HADH (IM) IEA Sus scrofa 57287 R-SSC-1482861 https://reactome.org/PathwayBrowser/#/R-SSC-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Sus scrofa 57287 R-SSC-1482867 https://reactome.org/PathwayBrowser/#/R-SSC-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Sus scrofa 57287 R-SSC-1482889 https://reactome.org/PathwayBrowser/#/R-SSC-1482889 DAG is acylated to TAG by DGAT1/2 IEA Sus scrofa 57287 R-SSC-1483002 https://reactome.org/PathwayBrowser/#/R-SSC-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Sus scrofa 57287 R-SSC-158832 https://reactome.org/PathwayBrowser/#/R-SSC-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Sus scrofa 57287 R-SSC-159425 https://reactome.org/PathwayBrowser/#/R-SSC-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 57287 R-SSC-159431 https://reactome.org/PathwayBrowser/#/R-SSC-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Sus scrofa 57287 R-SSC-159443 https://reactome.org/PathwayBrowser/#/R-SSC-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 57287 R-SSC-159566 https://reactome.org/PathwayBrowser/#/R-SSC-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Sus scrofa 57287 R-SSC-159567 https://reactome.org/PathwayBrowser/#/R-SSC-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Sus scrofa 57287 R-SSC-159574 https://reactome.org/PathwayBrowser/#/R-SSC-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Sus scrofa 57287 R-SSC-162683 https://reactome.org/PathwayBrowser/#/R-SSC-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Sus scrofa 57287 R-SSC-1678660 https://reactome.org/PathwayBrowser/#/R-SSC-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Sus scrofa 57287 R-SSC-174959 https://reactome.org/PathwayBrowser/#/R-SSC-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Sus scrofa 57287 R-SSC-177157 https://reactome.org/PathwayBrowser/#/R-SSC-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Sus scrofa 57287 R-SSC-189442 https://reactome.org/PathwayBrowser/#/R-SSC-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Sus scrofa 57287 R-SSC-191323 https://reactome.org/PathwayBrowser/#/R-SSC-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Sus scrofa 57287 R-SSC-191352 https://reactome.org/PathwayBrowser/#/R-SSC-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Sus scrofa 57287 R-SSC-192137 https://reactome.org/PathwayBrowser/#/R-SSC-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 57287 R-SSC-192312 https://reactome.org/PathwayBrowser/#/R-SSC-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Sus scrofa 57287 R-SSC-193385 https://reactome.org/PathwayBrowser/#/R-SSC-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Sus scrofa 57287 R-SSC-193401 https://reactome.org/PathwayBrowser/#/R-SSC-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 57287 R-SSC-193407 https://reactome.org/PathwayBrowser/#/R-SSC-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 57287 R-SSC-193424 https://reactome.org/PathwayBrowser/#/R-SSC-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 57287 R-SSC-193491 https://reactome.org/PathwayBrowser/#/R-SSC-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Sus scrofa 57287 R-SSC-193711 https://reactome.org/PathwayBrowser/#/R-SSC-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 57287 R-SSC-193727 https://reactome.org/PathwayBrowser/#/R-SSC-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 57287 R-SSC-193743 https://reactome.org/PathwayBrowser/#/R-SSC-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 57287 R-SSC-193766 https://reactome.org/PathwayBrowser/#/R-SSC-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 57287 R-SSC-196773 https://reactome.org/PathwayBrowser/#/R-SSC-196773 COASY phosphorylates DP-CoA IEA Sus scrofa 57287 R-SSC-196857 https://reactome.org/PathwayBrowser/#/R-SSC-196857 PANK2 phosphorylates PanK IEA Sus scrofa 57287 R-SSC-199202 https://reactome.org/PathwayBrowser/#/R-SSC-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Sus scrofa 57287 R-SSC-199216 https://reactome.org/PathwayBrowser/#/R-SSC-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Sus scrofa 57287 R-SSC-200406 https://reactome.org/PathwayBrowser/#/R-SSC-200406 CPT1A,B transfers PALM to CAR IEA Sus scrofa 57287 R-SSC-200410 https://reactome.org/PathwayBrowser/#/R-SSC-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Sus scrofa 57287 R-SSC-201035 https://reactome.org/PathwayBrowser/#/R-SSC-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Sus scrofa 57287 R-SSC-2046083 https://reactome.org/PathwayBrowser/#/R-SSC-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Sus scrofa 57287 R-SSC-2046085 https://reactome.org/PathwayBrowser/#/R-SSC-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Sus scrofa 57287 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa 57287 R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 57287 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa 57287 R-SSC-2046095 https://reactome.org/PathwayBrowser/#/R-SSC-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Sus scrofa 57287 R-SSC-2046098 https://reactome.org/PathwayBrowser/#/R-SSC-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Sus scrofa 57287 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa 57287 R-SSC-2066779 https://reactome.org/PathwayBrowser/#/R-SSC-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Sus scrofa 57287 R-SSC-2066788 https://reactome.org/PathwayBrowser/#/R-SSC-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Sus scrofa 57287 R-SSC-2090085 https://reactome.org/PathwayBrowser/#/R-SSC-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Sus scrofa 57287 R-SSC-209792 https://reactome.org/PathwayBrowser/#/R-SSC-209792 N-acetylation of serotonin IEA Sus scrofa 57287 R-SSC-2465919 https://reactome.org/PathwayBrowser/#/R-SSC-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Sus scrofa 57287 R-SSC-2468039 https://reactome.org/PathwayBrowser/#/R-SSC-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Sus scrofa 57287 R-SSC-2473152 https://reactome.org/PathwayBrowser/#/R-SSC-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Sus scrofa 57287 R-SSC-2534087 https://reactome.org/PathwayBrowser/#/R-SSC-2534087 NMT1/2 transfer MYS to GNAT1 IEA Sus scrofa 57287 R-SSC-2545203 https://reactome.org/PathwayBrowser/#/R-SSC-2545203 Deacetylation of cleaved cohesin IEA Sus scrofa 57287 R-SSC-2545253 https://reactome.org/PathwayBrowser/#/R-SSC-2545253 Deacetylation of cohesin IEA Sus scrofa 57287 R-SSC-264622 https://reactome.org/PathwayBrowser/#/R-SSC-264622 Cho is acetylated to AcCho by CHAT IEA Sus scrofa 57287 R-SSC-3318413 https://reactome.org/PathwayBrowser/#/R-SSC-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Sus scrofa 57287 R-SSC-3318415 https://reactome.org/PathwayBrowser/#/R-SSC-3318415 ATF2 acetylates histone H2B, H4 IEA Sus scrofa 57287 R-SSC-3318486 https://reactome.org/PathwayBrowser/#/R-SSC-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Sus scrofa 57287 R-SSC-3321805 https://reactome.org/PathwayBrowser/#/R-SSC-3321805 NSL acetylates histone H4 IEA Sus scrofa 57287 R-SSC-3321883 https://reactome.org/PathwayBrowser/#/R-SSC-3321883 MSL acetylates histone H4 IEA Sus scrofa 57287 R-SSC-3371554 https://reactome.org/PathwayBrowser/#/R-SSC-3371554 HSF1 acetylation at Lys80 IEA Sus scrofa 57287 R-SSC-351207 https://reactome.org/PathwayBrowser/#/R-SSC-351207 Spermine => N-acetylated spermine IEA Sus scrofa 57287 R-SSC-351208 https://reactome.org/PathwayBrowser/#/R-SSC-351208 Spermidine => N-acetylated spermidine IEA Sus scrofa 57287 R-SSC-3662318 https://reactome.org/PathwayBrowser/#/R-SSC-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Sus scrofa 57287 R-SSC-3662335 https://reactome.org/PathwayBrowser/#/R-SSC-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Sus scrofa 57287 R-SSC-389622 https://reactome.org/PathwayBrowser/#/R-SSC-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 57287 R-SSC-389632 https://reactome.org/PathwayBrowser/#/R-SSC-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 57287 R-SSC-390250 https://reactome.org/PathwayBrowser/#/R-SSC-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Sus scrofa 57287 R-SSC-390281 https://reactome.org/PathwayBrowser/#/R-SSC-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Sus scrofa 57287 R-SSC-390284 https://reactome.org/PathwayBrowser/#/R-SSC-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Sus scrofa 57287 R-SSC-390291 https://reactome.org/PathwayBrowser/#/R-SSC-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Sus scrofa 57287 R-SSC-390304 https://reactome.org/PathwayBrowser/#/R-SSC-390304 acetyl-CoA + H2O => acetate + CoASH IEA Sus scrofa 57287 R-SSC-390425 https://reactome.org/PathwayBrowser/#/R-SSC-390425 FAR1 reduces PalmCoA to HXOL IEA Sus scrofa 57287 R-SSC-390438 https://reactome.org/PathwayBrowser/#/R-SSC-390438 FAR2 reduces PalmCoA to HXOL IEA Sus scrofa 57287 R-SSC-428127 https://reactome.org/PathwayBrowser/#/R-SSC-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Sus scrofa 57287 R-SSC-428185 https://reactome.org/PathwayBrowser/#/R-SSC-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Sus scrofa 57287 R-SSC-434382 https://reactome.org/PathwayBrowser/#/R-SSC-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Sus scrofa 57287 R-SSC-449734 https://reactome.org/PathwayBrowser/#/R-SSC-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Sus scrofa 57287 R-SSC-449911 https://reactome.org/PathwayBrowser/#/R-SSC-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Sus scrofa 57287 R-SSC-5250938 https://reactome.org/PathwayBrowser/#/R-SSC-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Sus scrofa 57287 R-SSC-5358343 https://reactome.org/PathwayBrowser/#/R-SSC-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Sus scrofa 57287 R-SSC-548800 https://reactome.org/PathwayBrowser/#/R-SSC-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Sus scrofa 57287 R-SSC-548814 https://reactome.org/PathwayBrowser/#/R-SSC-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Sus scrofa 57287 R-SSC-548815 https://reactome.org/PathwayBrowser/#/R-SSC-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Sus scrofa 57287 R-SSC-548843 https://reactome.org/PathwayBrowser/#/R-SSC-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Sus scrofa 57287 R-SSC-549112 https://reactome.org/PathwayBrowser/#/R-SSC-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Sus scrofa 57287 R-SSC-549192 https://reactome.org/PathwayBrowser/#/R-SSC-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Sus scrofa 57287 R-SSC-5618328 https://reactome.org/PathwayBrowser/#/R-SSC-5618328 ATAT acetylates microtubules IEA Sus scrofa 57287 R-SSC-5618331 https://reactome.org/PathwayBrowser/#/R-SSC-5618331 HDAC6 deacetylates microtubules IEA Sus scrofa 57287 R-SSC-5628871 https://reactome.org/PathwayBrowser/#/R-SSC-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Sus scrofa 57287 R-SSC-5660660 https://reactome.org/PathwayBrowser/#/R-SSC-5660660 p300 acetylates RELA subunit IEA Sus scrofa 57287 R-SSC-5682044 https://reactome.org/PathwayBrowser/#/R-SSC-5682044 KAT5 acetylates ATM at DNA DSBs IEA Sus scrofa 57287 R-SSC-5682084 https://reactome.org/PathwayBrowser/#/R-SSC-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Sus scrofa 57287 R-SSC-5686304 https://reactome.org/PathwayBrowser/#/R-SSC-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Sus scrofa 57287 R-SSC-5690042 https://reactome.org/PathwayBrowser/#/R-SSC-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 57287 R-SSC-5690043 https://reactome.org/PathwayBrowser/#/R-SSC-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 57287 R-SSC-5690046 https://reactome.org/PathwayBrowser/#/R-SSC-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Sus scrofa 57287 R-SSC-5690066 https://reactome.org/PathwayBrowser/#/R-SSC-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 57287 R-SSC-5694494 https://reactome.org/PathwayBrowser/#/R-SSC-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Sus scrofa 57287 R-SSC-5695957 https://reactome.org/PathwayBrowser/#/R-SSC-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Sus scrofa 57287 R-SSC-5696004 https://reactome.org/PathwayBrowser/#/R-SSC-5696004 ACSF2 ligates CoA-SH to MCFA IEA Sus scrofa 57287 R-SSC-5696007 https://reactome.org/PathwayBrowser/#/R-SSC-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Sus scrofa 57287 R-SSC-5696448 https://reactome.org/PathwayBrowser/#/R-SSC-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Sus scrofa 57287 R-SSC-6792712 https://reactome.org/PathwayBrowser/#/R-SSC-6792712 KAT5 acetylates ATM at shortened telomeres IEA Sus scrofa 57287 R-SSC-6800334 https://reactome.org/PathwayBrowser/#/R-SSC-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Sus scrofa 57287 R-SSC-6805638 https://reactome.org/PathwayBrowser/#/R-SSC-6805638 KAT6A acetylates TP53 IEA Sus scrofa 57287 R-SSC-6811508 https://reactome.org/PathwayBrowser/#/R-SSC-6811508 ING2-bound EP300 acetylates TP53 IEA Sus scrofa 57287 R-SSC-70542 https://reactome.org/PathwayBrowser/#/R-SSC-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Sus scrofa 57287 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 57287 R-SSC-70844 https://reactome.org/PathwayBrowser/#/R-SSC-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Sus scrofa 57287 R-SSC-70881 https://reactome.org/PathwayBrowser/#/R-SSC-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Sus scrofa 57287 R-SSC-70893 https://reactome.org/PathwayBrowser/#/R-SSC-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Sus scrofa 57287 R-SSC-70975 https://reactome.org/PathwayBrowser/#/R-SSC-70975 CS acetylates OA to citrate IEA Sus scrofa 57287 R-SSC-70997 https://reactome.org/PathwayBrowser/#/R-SSC-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Sus scrofa 57287 R-SSC-71037 https://reactome.org/PathwayBrowser/#/R-SSC-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Sus scrofa 57287 R-SSC-71735 https://reactome.org/PathwayBrowser/#/R-SSC-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Sus scrofa 57287 R-SSC-71775 https://reactome.org/PathwayBrowser/#/R-SSC-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Sus scrofa 57287 R-SSC-73916 https://reactome.org/PathwayBrowser/#/R-SSC-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Sus scrofa 57287 R-SSC-73918 https://reactome.org/PathwayBrowser/#/R-SSC-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Sus scrofa 57287 R-SSC-74181 https://reactome.org/PathwayBrowser/#/R-SSC-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Sus scrofa 57287 R-SSC-75848 https://reactome.org/PathwayBrowser/#/R-SSC-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Sus scrofa 57287 R-SSC-75872 https://reactome.org/PathwayBrowser/#/R-SSC-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Sus scrofa 57287 R-SSC-75879 https://reactome.org/PathwayBrowser/#/R-SSC-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Sus scrofa 57287 R-SSC-75885 https://reactome.org/PathwayBrowser/#/R-SSC-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Sus scrofa 57287 R-SSC-75886 https://reactome.org/PathwayBrowser/#/R-SSC-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Sus scrofa 57287 R-SSC-75900 https://reactome.org/PathwayBrowser/#/R-SSC-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Sus scrofa 57287 R-SSC-77271 https://reactome.org/PathwayBrowser/#/R-SSC-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Sus scrofa 57287 R-SSC-77304 https://reactome.org/PathwayBrowser/#/R-SSC-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Sus scrofa 57287 R-SSC-77309 https://reactome.org/PathwayBrowser/#/R-SSC-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Sus scrofa 57287 R-SSC-77321 https://reactome.org/PathwayBrowser/#/R-SSC-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Sus scrofa 57287 R-SSC-77329 https://reactome.org/PathwayBrowser/#/R-SSC-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Sus scrofa 57287 R-SSC-77340 https://reactome.org/PathwayBrowser/#/R-SSC-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Sus scrofa 57287 R-SSC-8848215 https://reactome.org/PathwayBrowser/#/R-SSC-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Sus scrofa 57287 R-SSC-8848580 https://reactome.org/PathwayBrowser/#/R-SSC-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Sus scrofa 57287 R-SSC-8848582 https://reactome.org/PathwayBrowser/#/R-SSC-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Sus scrofa 57287 R-SSC-8848585 https://reactome.org/PathwayBrowser/#/R-SSC-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Sus scrofa 57287 R-SSC-8849345 https://reactome.org/PathwayBrowser/#/R-SSC-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Sus scrofa 57287 R-SSC-8874745 https://reactome.org/PathwayBrowser/#/R-SSC-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Sus scrofa 57287 R-SSC-8875071 https://reactome.org/PathwayBrowser/#/R-SSC-8875071 ACSS3 ligates CoA to CH3COO- IEA Sus scrofa 57287 R-SSC-8876696 https://reactome.org/PathwayBrowser/#/R-SSC-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Sus scrofa 57287 R-SSC-8933547 https://reactome.org/PathwayBrowser/#/R-SSC-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Sus scrofa 57287 R-SSC-8951966 https://reactome.org/PathwayBrowser/#/R-SSC-8951966 EP300 acetylates RUNX3 IEA Sus scrofa 57287 R-SSC-8954468 https://reactome.org/PathwayBrowser/#/R-SSC-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Sus scrofa 57287 R-SSC-9021072 https://reactome.org/PathwayBrowser/#/R-SSC-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Sus scrofa 57287 R-SSC-9620515 https://reactome.org/PathwayBrowser/#/R-SSC-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Sus scrofa 57287 R-SSC-9647982 https://reactome.org/PathwayBrowser/#/R-SSC-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Sus scrofa 57287 R-SSC-9701531 https://reactome.org/PathwayBrowser/#/R-SSC-9701531 p-Y705,S727 STAT3 is acetylated IEA Sus scrofa 57287 R-SSC-9734535 https://reactome.org/PathwayBrowser/#/R-SSC-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Sus scrofa 57287 R-SSC-9749971 https://reactome.org/PathwayBrowser/#/R-SSC-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Sus scrofa 57287 R-SSC-9750001 https://reactome.org/PathwayBrowser/#/R-SSC-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Sus scrofa 57287 R-SSC-9753676 https://reactome.org/PathwayBrowser/#/R-SSC-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Sus scrofa 57287 R-SSC-9760081 https://reactome.org/PathwayBrowser/#/R-SSC-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Sus scrofa 57287 R-SSC-9825747 https://reactome.org/PathwayBrowser/#/R-SSC-9825747 CREBBP acetylates HINT1 dimer IEA Sus scrofa 57287 R-SSC-9837333 https://reactome.org/PathwayBrowser/#/R-SSC-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Sus scrofa 57287 R-SSC-9837337 https://reactome.org/PathwayBrowser/#/R-SSC-9837337 DCAKD phosphorylates DP-CoA IEA Sus scrofa 57287 R-SSC-9853512 https://reactome.org/PathwayBrowser/#/R-SSC-9853512 DLST transfers succinyl to CoA IEA Sus scrofa 57287 R-SSC-9854415 https://reactome.org/PathwayBrowser/#/R-SSC-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Sus scrofa 57287 R-SSC-9861667 https://reactome.org/PathwayBrowser/#/R-SSC-9861667 DLAT trimer transfers acetyl to CoA IEA Sus scrofa 57287 R-XTR-1482533 https://reactome.org/PathwayBrowser/#/R-XTR-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Xenopus tropicalis 57287 R-XTR-1482539 https://reactome.org/PathwayBrowser/#/R-XTR-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Xenopus tropicalis 57287 R-XTR-1482547 https://reactome.org/PathwayBrowser/#/R-XTR-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Xenopus tropicalis 57287 R-XTR-1482598 https://reactome.org/PathwayBrowser/#/R-XTR-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Xenopus tropicalis 57287 R-XTR-1482626 https://reactome.org/PathwayBrowser/#/R-XTR-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Xenopus tropicalis 57287 R-XTR-1482635 https://reactome.org/PathwayBrowser/#/R-XTR-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Xenopus tropicalis 57287 R-XTR-1482636 https://reactome.org/PathwayBrowser/#/R-XTR-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Xenopus tropicalis 57287 R-XTR-1482646 https://reactome.org/PathwayBrowser/#/R-XTR-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Xenopus tropicalis 57287 R-XTR-1482667 https://reactome.org/PathwayBrowser/#/R-XTR-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Xenopus tropicalis 57287 R-XTR-1482691 https://reactome.org/PathwayBrowser/#/R-XTR-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Xenopus tropicalis 57287 R-XTR-1482695 https://reactome.org/PathwayBrowser/#/R-XTR-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Xenopus tropicalis 57287 R-XTR-1482775 https://reactome.org/PathwayBrowser/#/R-XTR-1482775 MLCL is acylated to CL by HADH (IM) IEA Xenopus tropicalis 57287 R-XTR-1482861 https://reactome.org/PathwayBrowser/#/R-XTR-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Xenopus tropicalis 57287 R-XTR-1482867 https://reactome.org/PathwayBrowser/#/R-XTR-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Xenopus tropicalis 57287 R-XTR-1482889 https://reactome.org/PathwayBrowser/#/R-XTR-1482889 DAG is acylated to TAG by DGAT1/2 IEA Xenopus tropicalis 57287 R-XTR-1483002 https://reactome.org/PathwayBrowser/#/R-XTR-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Xenopus tropicalis 57287 R-XTR-159425 https://reactome.org/PathwayBrowser/#/R-XTR-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 57287 R-XTR-159431 https://reactome.org/PathwayBrowser/#/R-XTR-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Xenopus tropicalis 57287 R-XTR-159443 https://reactome.org/PathwayBrowser/#/R-XTR-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 57287 R-XTR-159566 https://reactome.org/PathwayBrowser/#/R-XTR-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Xenopus tropicalis 57287 R-XTR-159567 https://reactome.org/PathwayBrowser/#/R-XTR-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Xenopus tropicalis 57287 R-XTR-159574 https://reactome.org/PathwayBrowser/#/R-XTR-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Xenopus tropicalis 57287 R-XTR-162683 https://reactome.org/PathwayBrowser/#/R-XTR-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Xenopus tropicalis 57287 R-XTR-1678660 https://reactome.org/PathwayBrowser/#/R-XTR-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Xenopus tropicalis 57287 R-XTR-177157 https://reactome.org/PathwayBrowser/#/R-XTR-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 57287 R-XTR-189442 https://reactome.org/PathwayBrowser/#/R-XTR-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Xenopus tropicalis 57287 R-XTR-191352 https://reactome.org/PathwayBrowser/#/R-XTR-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Xenopus tropicalis 57287 R-XTR-192137 https://reactome.org/PathwayBrowser/#/R-XTR-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 57287 R-XTR-192312 https://reactome.org/PathwayBrowser/#/R-XTR-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Xenopus tropicalis 57287 R-XTR-193385 https://reactome.org/PathwayBrowser/#/R-XTR-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Xenopus tropicalis 57287 R-XTR-193401 https://reactome.org/PathwayBrowser/#/R-XTR-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 57287 R-XTR-193407 https://reactome.org/PathwayBrowser/#/R-XTR-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 57287 R-XTR-193424 https://reactome.org/PathwayBrowser/#/R-XTR-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 57287 R-XTR-193491 https://reactome.org/PathwayBrowser/#/R-XTR-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Xenopus tropicalis 57287 R-XTR-193711 https://reactome.org/PathwayBrowser/#/R-XTR-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 57287 R-XTR-193727 https://reactome.org/PathwayBrowser/#/R-XTR-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 57287 R-XTR-193743 https://reactome.org/PathwayBrowser/#/R-XTR-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 57287 R-XTR-193766 https://reactome.org/PathwayBrowser/#/R-XTR-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 57287 R-XTR-196773 https://reactome.org/PathwayBrowser/#/R-XTR-196773 COASY phosphorylates DP-CoA IEA Xenopus tropicalis 57287 R-XTR-196857 https://reactome.org/PathwayBrowser/#/R-XTR-196857 PANK2 phosphorylates PanK IEA Xenopus tropicalis 57287 R-XTR-199202 https://reactome.org/PathwayBrowser/#/R-XTR-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Xenopus tropicalis 57287 R-XTR-199216 https://reactome.org/PathwayBrowser/#/R-XTR-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix IEA Xenopus tropicalis 57287 R-XTR-200406 https://reactome.org/PathwayBrowser/#/R-XTR-200406 CPT1A,B transfers PALM to CAR IEA Xenopus tropicalis 57287 R-XTR-200410 https://reactome.org/PathwayBrowser/#/R-XTR-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Xenopus tropicalis 57287 R-XTR-201035 https://reactome.org/PathwayBrowser/#/R-XTR-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Xenopus tropicalis 57287 R-XTR-2046083 https://reactome.org/PathwayBrowser/#/R-XTR-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-2046085 https://reactome.org/PathwayBrowser/#/R-XTR-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-2046088 https://reactome.org/PathwayBrowser/#/R-XTR-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-2046090 https://reactome.org/PathwayBrowser/#/R-XTR-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-2046094 https://reactome.org/PathwayBrowser/#/R-XTR-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-2046095 https://reactome.org/PathwayBrowser/#/R-XTR-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-2046098 https://reactome.org/PathwayBrowser/#/R-XTR-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-2046100 https://reactome.org/PathwayBrowser/#/R-XTR-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-2066779 https://reactome.org/PathwayBrowser/#/R-XTR-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Xenopus tropicalis 57287 R-XTR-2066788 https://reactome.org/PathwayBrowser/#/R-XTR-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Xenopus tropicalis 57287 R-XTR-2090085 https://reactome.org/PathwayBrowser/#/R-XTR-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Xenopus tropicalis 57287 R-XTR-2465919 https://reactome.org/PathwayBrowser/#/R-XTR-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Xenopus tropicalis 57287 R-XTR-2534087 https://reactome.org/PathwayBrowser/#/R-XTR-2534087 NMT1/2 transfer MYS to GNAT1 IEA Xenopus tropicalis 57287 R-XTR-3318415 https://reactome.org/PathwayBrowser/#/R-XTR-3318415 ATF2 acetylates histone H2B, H4 IEA Xenopus tropicalis 57287 R-XTR-351207 https://reactome.org/PathwayBrowser/#/R-XTR-351207 Spermine => N-acetylated spermine IEA Xenopus tropicalis 57287 R-XTR-351208 https://reactome.org/PathwayBrowser/#/R-XTR-351208 Spermidine => N-acetylated spermidine IEA Xenopus tropicalis 57287 R-XTR-3662335 https://reactome.org/PathwayBrowser/#/R-XTR-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Xenopus tropicalis 57287 R-XTR-389622 https://reactome.org/PathwayBrowser/#/R-XTR-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 57287 R-XTR-389632 https://reactome.org/PathwayBrowser/#/R-XTR-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 57287 R-XTR-390250 https://reactome.org/PathwayBrowser/#/R-XTR-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Xenopus tropicalis 57287 R-XTR-390281 https://reactome.org/PathwayBrowser/#/R-XTR-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Xenopus tropicalis 57287 R-XTR-390284 https://reactome.org/PathwayBrowser/#/R-XTR-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Xenopus tropicalis 57287 R-XTR-390291 https://reactome.org/PathwayBrowser/#/R-XTR-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Xenopus tropicalis 57287 R-XTR-390304 https://reactome.org/PathwayBrowser/#/R-XTR-390304 acetyl-CoA + H2O => acetate + CoASH IEA Xenopus tropicalis 57287 R-XTR-428127 https://reactome.org/PathwayBrowser/#/R-XTR-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Xenopus tropicalis 57287 R-XTR-428185 https://reactome.org/PathwayBrowser/#/R-XTR-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Xenopus tropicalis 57287 R-XTR-434382 https://reactome.org/PathwayBrowser/#/R-XTR-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Xenopus tropicalis 57287 R-XTR-449734 https://reactome.org/PathwayBrowser/#/R-XTR-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Xenopus tropicalis 57287 R-XTR-449911 https://reactome.org/PathwayBrowser/#/R-XTR-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Xenopus tropicalis 57287 R-XTR-5358343 https://reactome.org/PathwayBrowser/#/R-XTR-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Xenopus tropicalis 57287 R-XTR-548800 https://reactome.org/PathwayBrowser/#/R-XTR-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Xenopus tropicalis 57287 R-XTR-548814 https://reactome.org/PathwayBrowser/#/R-XTR-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Xenopus tropicalis 57287 R-XTR-548815 https://reactome.org/PathwayBrowser/#/R-XTR-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Xenopus tropicalis 57287 R-XTR-548843 https://reactome.org/PathwayBrowser/#/R-XTR-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Xenopus tropicalis 57287 R-XTR-549112 https://reactome.org/PathwayBrowser/#/R-XTR-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Xenopus tropicalis 57287 R-XTR-549192 https://reactome.org/PathwayBrowser/#/R-XTR-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Xenopus tropicalis 57287 R-XTR-5618328 https://reactome.org/PathwayBrowser/#/R-XTR-5618328 ATAT acetylates microtubules IEA Xenopus tropicalis 57287 R-XTR-5628871 https://reactome.org/PathwayBrowser/#/R-XTR-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Xenopus tropicalis 57287 R-XTR-5682084 https://reactome.org/PathwayBrowser/#/R-XTR-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Xenopus tropicalis 57287 R-XTR-5686304 https://reactome.org/PathwayBrowser/#/R-XTR-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Xenopus tropicalis 57287 R-XTR-5690042 https://reactome.org/PathwayBrowser/#/R-XTR-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 57287 R-XTR-5690043 https://reactome.org/PathwayBrowser/#/R-XTR-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 57287 R-XTR-5690046 https://reactome.org/PathwayBrowser/#/R-XTR-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Xenopus tropicalis 57287 R-XTR-5690066 https://reactome.org/PathwayBrowser/#/R-XTR-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 57287 R-XTR-5694494 https://reactome.org/PathwayBrowser/#/R-XTR-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Xenopus tropicalis 57287 R-XTR-5696004 https://reactome.org/PathwayBrowser/#/R-XTR-5696004 ACSF2 ligates CoA-SH to MCFA IEA Xenopus tropicalis 57287 R-XTR-5696424 https://reactome.org/PathwayBrowser/#/R-XTR-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Xenopus tropicalis 57287 R-XTR-5696448 https://reactome.org/PathwayBrowser/#/R-XTR-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG IEA Xenopus tropicalis 57287 R-XTR-6800334 https://reactome.org/PathwayBrowser/#/R-XTR-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Xenopus tropicalis 57287 R-XTR-6805638 https://reactome.org/PathwayBrowser/#/R-XTR-6805638 KAT6A acetylates TP53 IEA Xenopus tropicalis 57287 R-XTR-6811508 https://reactome.org/PathwayBrowser/#/R-XTR-6811508 ING2-bound EP300 acetylates TP53 IEA Xenopus tropicalis 57287 R-XTR-70542 https://reactome.org/PathwayBrowser/#/R-XTR-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Xenopus tropicalis 57287 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 57287 R-XTR-70844 https://reactome.org/PathwayBrowser/#/R-XTR-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Xenopus tropicalis 57287 R-XTR-70893 https://reactome.org/PathwayBrowser/#/R-XTR-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 57287 R-XTR-70975 https://reactome.org/PathwayBrowser/#/R-XTR-70975 CS acetylates OA to citrate IEA Xenopus tropicalis 57287 R-XTR-70997 https://reactome.org/PathwayBrowser/#/R-XTR-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Xenopus tropicalis 57287 R-XTR-71037 https://reactome.org/PathwayBrowser/#/R-XTR-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 57287 R-XTR-71735 https://reactome.org/PathwayBrowser/#/R-XTR-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Xenopus tropicalis 57287 R-XTR-71775 https://reactome.org/PathwayBrowser/#/R-XTR-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Xenopus tropicalis 57287 R-XTR-73916 https://reactome.org/PathwayBrowser/#/R-XTR-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Xenopus tropicalis 57287 R-XTR-74181 https://reactome.org/PathwayBrowser/#/R-XTR-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Xenopus tropicalis 57287 R-XTR-75848 https://reactome.org/PathwayBrowser/#/R-XTR-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Xenopus tropicalis 57287 R-XTR-75872 https://reactome.org/PathwayBrowser/#/R-XTR-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Xenopus tropicalis 57287 R-XTR-75879 https://reactome.org/PathwayBrowser/#/R-XTR-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Xenopus tropicalis 57287 R-XTR-75885 https://reactome.org/PathwayBrowser/#/R-XTR-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Xenopus tropicalis 57287 R-XTR-75886 https://reactome.org/PathwayBrowser/#/R-XTR-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Xenopus tropicalis 57287 R-XTR-75900 https://reactome.org/PathwayBrowser/#/R-XTR-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Xenopus tropicalis 57287 R-XTR-77271 https://reactome.org/PathwayBrowser/#/R-XTR-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Xenopus tropicalis 57287 R-XTR-77304 https://reactome.org/PathwayBrowser/#/R-XTR-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-77309 https://reactome.org/PathwayBrowser/#/R-XTR-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-77321 https://reactome.org/PathwayBrowser/#/R-XTR-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-77329 https://reactome.org/PathwayBrowser/#/R-XTR-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-77340 https://reactome.org/PathwayBrowser/#/R-XTR-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Xenopus tropicalis 57287 R-XTR-8848215 https://reactome.org/PathwayBrowser/#/R-XTR-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Xenopus tropicalis 57287 R-XTR-8848580 https://reactome.org/PathwayBrowser/#/R-XTR-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG IEA Xenopus tropicalis 57287 R-XTR-8848582 https://reactome.org/PathwayBrowser/#/R-XTR-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Xenopus tropicalis 57287 R-XTR-8848585 https://reactome.org/PathwayBrowser/#/R-XTR-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Xenopus tropicalis 57287 R-XTR-8849345 https://reactome.org/PathwayBrowser/#/R-XTR-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Xenopus tropicalis 57287 R-XTR-8874745 https://reactome.org/PathwayBrowser/#/R-XTR-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Xenopus tropicalis 57287 R-XTR-8875071 https://reactome.org/PathwayBrowser/#/R-XTR-8875071 ACSS3 ligates CoA to CH3COO- IEA Xenopus tropicalis 57287 R-XTR-8876696 https://reactome.org/PathwayBrowser/#/R-XTR-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Xenopus tropicalis 57287 R-XTR-8954468 https://reactome.org/PathwayBrowser/#/R-XTR-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Xenopus tropicalis 57287 R-XTR-9021072 https://reactome.org/PathwayBrowser/#/R-XTR-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Xenopus tropicalis 57287 R-XTR-9620515 https://reactome.org/PathwayBrowser/#/R-XTR-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Xenopus tropicalis 57287 R-XTR-9701531 https://reactome.org/PathwayBrowser/#/R-XTR-9701531 p-Y705,S727 STAT3 is acetylated IEA Xenopus tropicalis 57287 R-XTR-9734535 https://reactome.org/PathwayBrowser/#/R-XTR-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Xenopus tropicalis 57287 R-XTR-9749971 https://reactome.org/PathwayBrowser/#/R-XTR-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Xenopus tropicalis 57287 R-XTR-9750001 https://reactome.org/PathwayBrowser/#/R-XTR-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Xenopus tropicalis 57287 R-XTR-9760081 https://reactome.org/PathwayBrowser/#/R-XTR-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Xenopus tropicalis 57287 R-XTR-9837333 https://reactome.org/PathwayBrowser/#/R-XTR-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Xenopus tropicalis 57287 R-XTR-9837337 https://reactome.org/PathwayBrowser/#/R-XTR-9837337 DCAKD phosphorylates DP-CoA IEA Xenopus tropicalis 57287 R-XTR-9853512 https://reactome.org/PathwayBrowser/#/R-XTR-9853512 DLST transfers succinyl to CoA IEA Xenopus tropicalis 57287 R-XTR-9854415 https://reactome.org/PathwayBrowser/#/R-XTR-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Xenopus tropicalis 57287 R-XTR-9861667 https://reactome.org/PathwayBrowser/#/R-XTR-9861667 DLAT trimer transfers acetyl to CoA IEA Xenopus tropicalis 57288 R-BTA-158832 https://reactome.org/PathwayBrowser/#/R-BTA-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Bos taurus 57288 R-BTA-1678660 https://reactome.org/PathwayBrowser/#/R-BTA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Bos taurus 57288 R-BTA-174959 https://reactome.org/PathwayBrowser/#/R-BTA-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Bos taurus 57288 R-BTA-191323 https://reactome.org/PathwayBrowser/#/R-BTA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Bos taurus 57288 R-BTA-200555 https://reactome.org/PathwayBrowser/#/R-BTA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Bos taurus 57288 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 57288 R-BTA-2066788 https://reactome.org/PathwayBrowser/#/R-BTA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Bos taurus 57288 R-BTA-2090085 https://reactome.org/PathwayBrowser/#/R-BTA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Bos taurus 57288 R-BTA-209792 https://reactome.org/PathwayBrowser/#/R-BTA-209792 N-acetylation of serotonin IEA Bos taurus 57288 R-BTA-2468039 https://reactome.org/PathwayBrowser/#/R-BTA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Bos taurus 57288 R-BTA-2473152 https://reactome.org/PathwayBrowser/#/R-BTA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Bos taurus 57288 R-BTA-2545203 https://reactome.org/PathwayBrowser/#/R-BTA-2545203 Deacetylation of cleaved cohesin IEA Bos taurus 57288 R-BTA-2545253 https://reactome.org/PathwayBrowser/#/R-BTA-2545253 Deacetylation of cohesin IEA Bos taurus 57288 R-BTA-264622 https://reactome.org/PathwayBrowser/#/R-BTA-264622 Cho is acetylated to AcCho by CHAT IEA Bos taurus 57288 R-BTA-3318413 https://reactome.org/PathwayBrowser/#/R-BTA-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Bos taurus 57288 R-BTA-3318486 https://reactome.org/PathwayBrowser/#/R-BTA-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Bos taurus 57288 R-BTA-3321805 https://reactome.org/PathwayBrowser/#/R-BTA-3321805 NSL acetylates histone H4 IEA Bos taurus 57288 R-BTA-3321883 https://reactome.org/PathwayBrowser/#/R-BTA-3321883 MSL acetylates histone H4 IEA Bos taurus 57288 R-BTA-3371554 https://reactome.org/PathwayBrowser/#/R-BTA-3371554 HSF1 acetylation at Lys80 IEA Bos taurus 57288 R-BTA-351207 https://reactome.org/PathwayBrowser/#/R-BTA-351207 Spermine => N-acetylated spermine IEA Bos taurus 57288 R-BTA-351208 https://reactome.org/PathwayBrowser/#/R-BTA-351208 Spermidine => N-acetylated spermidine IEA Bos taurus 57288 R-BTA-3662318 https://reactome.org/PathwayBrowser/#/R-BTA-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Bos taurus 57288 R-BTA-3662335 https://reactome.org/PathwayBrowser/#/R-BTA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Bos taurus 57288 R-BTA-390250 https://reactome.org/PathwayBrowser/#/R-BTA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Bos taurus 57288 R-BTA-390291 https://reactome.org/PathwayBrowser/#/R-BTA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Bos taurus 57288 R-BTA-390304 https://reactome.org/PathwayBrowser/#/R-BTA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Bos taurus 57288 R-BTA-449734 https://reactome.org/PathwayBrowser/#/R-BTA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Bos taurus 57288 R-BTA-449911 https://reactome.org/PathwayBrowser/#/R-BTA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Bos taurus 57288 R-BTA-5250938 https://reactome.org/PathwayBrowser/#/R-BTA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Bos taurus 57288 R-BTA-5618328 https://reactome.org/PathwayBrowser/#/R-BTA-5618328 ATAT acetylates microtubules IEA Bos taurus 57288 R-BTA-5618331 https://reactome.org/PathwayBrowser/#/R-BTA-5618331 HDAC6 deacetylates microtubules IEA Bos taurus 57288 R-BTA-5628871 https://reactome.org/PathwayBrowser/#/R-BTA-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Bos taurus 57288 R-BTA-5660660 https://reactome.org/PathwayBrowser/#/R-BTA-5660660 p300 acetylates RELA subunit IEA Bos taurus 57288 R-BTA-5682044 https://reactome.org/PathwayBrowser/#/R-BTA-5682044 KAT5 acetylates ATM at DNA DSBs IEA Bos taurus 57288 R-BTA-6788597 https://reactome.org/PathwayBrowser/#/R-BTA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Bos taurus 57288 R-BTA-6792712 https://reactome.org/PathwayBrowser/#/R-BTA-6792712 KAT5 acetylates ATM at shortened telomeres IEA Bos taurus 57288 R-BTA-6805638 https://reactome.org/PathwayBrowser/#/R-BTA-6805638 KAT6A acetylates TP53 IEA Bos taurus 57288 R-BTA-6811508 https://reactome.org/PathwayBrowser/#/R-BTA-6811508 ING2-bound EP300 acetylates TP53 IEA Bos taurus 57288 R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 57288 R-BTA-70542 https://reactome.org/PathwayBrowser/#/R-BTA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Bos taurus 57288 R-BTA-70844 https://reactome.org/PathwayBrowser/#/R-BTA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Bos taurus 57288 R-BTA-70975 https://reactome.org/PathwayBrowser/#/R-BTA-70975 CS acetylates OA to citrate IEA Bos taurus 57288 R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 57288 R-BTA-71735 https://reactome.org/PathwayBrowser/#/R-BTA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Bos taurus 57288 R-BTA-727759 https://reactome.org/PathwayBrowser/#/R-BTA-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Bos taurus 57288 R-BTA-73916 https://reactome.org/PathwayBrowser/#/R-BTA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Bos taurus 57288 R-BTA-73918 https://reactome.org/PathwayBrowser/#/R-BTA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Bos taurus 57288 R-BTA-74180 https://reactome.org/PathwayBrowser/#/R-BTA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Bos taurus 57288 R-BTA-74181 https://reactome.org/PathwayBrowser/#/R-BTA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Bos taurus 57288 R-BTA-75848 https://reactome.org/PathwayBrowser/#/R-BTA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Bos taurus 57288 R-BTA-75851 https://reactome.org/PathwayBrowser/#/R-BTA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 57288 R-BTA-75872 https://reactome.org/PathwayBrowser/#/R-BTA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Bos taurus 57288 R-BTA-77271 https://reactome.org/PathwayBrowser/#/R-BTA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Bos taurus 57288 R-BTA-77304 https://reactome.org/PathwayBrowser/#/R-BTA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Bos taurus 57288 R-BTA-77309 https://reactome.org/PathwayBrowser/#/R-BTA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Bos taurus 57288 R-BTA-77321 https://reactome.org/PathwayBrowser/#/R-BTA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Bos taurus 57288 R-BTA-77329 https://reactome.org/PathwayBrowser/#/R-BTA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Bos taurus 57288 R-BTA-77340 https://reactome.org/PathwayBrowser/#/R-BTA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Bos taurus 57288 R-BTA-8848215 https://reactome.org/PathwayBrowser/#/R-BTA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Bos taurus 57288 R-BTA-8874745 https://reactome.org/PathwayBrowser/#/R-BTA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Bos taurus 57288 R-BTA-8875071 https://reactome.org/PathwayBrowser/#/R-BTA-8875071 ACSS3 ligates CoA to CH3COO- IEA Bos taurus 57288 R-BTA-8876889 https://reactome.org/PathwayBrowser/#/R-BTA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 57288 R-BTA-8951966 https://reactome.org/PathwayBrowser/#/R-BTA-8951966 EP300 acetylates RUNX3 IEA Bos taurus 57288 R-BTA-8954468 https://reactome.org/PathwayBrowser/#/R-BTA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Bos taurus 57288 R-BTA-9620515 https://reactome.org/PathwayBrowser/#/R-BTA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Bos taurus 57288 R-BTA-9701531 https://reactome.org/PathwayBrowser/#/R-BTA-9701531 p-Y705,S727 STAT3 is acetylated IEA Bos taurus 57288 R-BTA-9753676 https://reactome.org/PathwayBrowser/#/R-BTA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Bos taurus 57288 R-BTA-9760081 https://reactome.org/PathwayBrowser/#/R-BTA-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Bos taurus 57288 R-BTA-977317 https://reactome.org/PathwayBrowser/#/R-BTA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Bos taurus 57288 R-BTA-9825747 https://reactome.org/PathwayBrowser/#/R-BTA-9825747 CREBBP acetylates HINT1 dimer IEA Bos taurus 57288 R-BTA-9854415 https://reactome.org/PathwayBrowser/#/R-BTA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Bos taurus 57288 R-BTA-9861667 https://reactome.org/PathwayBrowser/#/R-BTA-9861667 DLAT trimer transfers acetyl to CoA IEA Bos taurus 57288 R-CEL-191323 https://reactome.org/PathwayBrowser/#/R-CEL-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Caenorhabditis elegans 57288 R-CEL-200555 https://reactome.org/PathwayBrowser/#/R-CEL-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Caenorhabditis elegans 57288 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 57288 R-CEL-2468039 https://reactome.org/PathwayBrowser/#/R-CEL-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Caenorhabditis elegans 57288 R-CEL-2473152 https://reactome.org/PathwayBrowser/#/R-CEL-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Caenorhabditis elegans 57288 R-CEL-264622 https://reactome.org/PathwayBrowser/#/R-CEL-264622 Cho is acetylated to AcCho by CHAT IEA Caenorhabditis elegans 57288 R-CEL-3318413 https://reactome.org/PathwayBrowser/#/R-CEL-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Caenorhabditis elegans 57288 R-CEL-3318415 https://reactome.org/PathwayBrowser/#/R-CEL-3318415 ATF2 acetylates histone H2B, H4 IEA Caenorhabditis elegans 57288 R-CEL-3318486 https://reactome.org/PathwayBrowser/#/R-CEL-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Caenorhabditis elegans 57288 R-CEL-351207 https://reactome.org/PathwayBrowser/#/R-CEL-351207 Spermine => N-acetylated spermine IEA Caenorhabditis elegans 57288 R-CEL-351208 https://reactome.org/PathwayBrowser/#/R-CEL-351208 Spermidine => N-acetylated spermidine IEA Caenorhabditis elegans 57288 R-CEL-3662318 https://reactome.org/PathwayBrowser/#/R-CEL-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Caenorhabditis elegans 57288 R-CEL-390291 https://reactome.org/PathwayBrowser/#/R-CEL-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Caenorhabditis elegans 57288 R-CEL-390304 https://reactome.org/PathwayBrowser/#/R-CEL-390304 acetyl-CoA + H2O => acetate + CoASH IEA Caenorhabditis elegans 57288 R-CEL-449734 https://reactome.org/PathwayBrowser/#/R-CEL-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Caenorhabditis elegans 57288 R-CEL-5250938 https://reactome.org/PathwayBrowser/#/R-CEL-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Caenorhabditis elegans 57288 R-CEL-6788597 https://reactome.org/PathwayBrowser/#/R-CEL-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Caenorhabditis elegans 57288 R-CEL-6805638 https://reactome.org/PathwayBrowser/#/R-CEL-6805638 KAT6A acetylates TP53 IEA Caenorhabditis elegans 57288 R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 57288 R-CEL-70844 https://reactome.org/PathwayBrowser/#/R-CEL-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Caenorhabditis elegans 57288 R-CEL-70975 https://reactome.org/PathwayBrowser/#/R-CEL-70975 CS acetylates OA to citrate IEA Caenorhabditis elegans 57288 R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 57288 R-CEL-71735 https://reactome.org/PathwayBrowser/#/R-CEL-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Caenorhabditis elegans 57288 R-CEL-727759 https://reactome.org/PathwayBrowser/#/R-CEL-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Caenorhabditis elegans 57288 R-CEL-73916 https://reactome.org/PathwayBrowser/#/R-CEL-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Caenorhabditis elegans 57288 R-CEL-73918 https://reactome.org/PathwayBrowser/#/R-CEL-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Caenorhabditis elegans 57288 R-CEL-74180 https://reactome.org/PathwayBrowser/#/R-CEL-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Caenorhabditis elegans 57288 R-CEL-74181 https://reactome.org/PathwayBrowser/#/R-CEL-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Caenorhabditis elegans 57288 R-CEL-75848 https://reactome.org/PathwayBrowser/#/R-CEL-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Caenorhabditis elegans 57288 R-CEL-75851 https://reactome.org/PathwayBrowser/#/R-CEL-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 57288 R-CEL-75872 https://reactome.org/PathwayBrowser/#/R-CEL-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Caenorhabditis elegans 57288 R-CEL-77271 https://reactome.org/PathwayBrowser/#/R-CEL-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Caenorhabditis elegans 57288 R-CEL-77304 https://reactome.org/PathwayBrowser/#/R-CEL-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Caenorhabditis elegans 57288 R-CEL-77309 https://reactome.org/PathwayBrowser/#/R-CEL-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Caenorhabditis elegans 57288 R-CEL-77321 https://reactome.org/PathwayBrowser/#/R-CEL-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Caenorhabditis elegans 57288 R-CEL-77329 https://reactome.org/PathwayBrowser/#/R-CEL-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Caenorhabditis elegans 57288 R-CEL-77340 https://reactome.org/PathwayBrowser/#/R-CEL-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Caenorhabditis elegans 57288 R-CEL-8874745 https://reactome.org/PathwayBrowser/#/R-CEL-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Caenorhabditis elegans 57288 R-CEL-8876889 https://reactome.org/PathwayBrowser/#/R-CEL-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 57288 R-CEL-8951966 https://reactome.org/PathwayBrowser/#/R-CEL-8951966 EP300 acetylates RUNX3 IEA Caenorhabditis elegans 57288 R-CEL-9620515 https://reactome.org/PathwayBrowser/#/R-CEL-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Caenorhabditis elegans 57288 R-CEL-9701531 https://reactome.org/PathwayBrowser/#/R-CEL-9701531 p-Y705,S727 STAT3 is acetylated IEA Caenorhabditis elegans 57288 R-CEL-9760081 https://reactome.org/PathwayBrowser/#/R-CEL-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Caenorhabditis elegans 57288 R-CEL-977317 https://reactome.org/PathwayBrowser/#/R-CEL-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Caenorhabditis elegans 57288 R-CEL-9825747 https://reactome.org/PathwayBrowser/#/R-CEL-9825747 CREBBP acetylates HINT1 dimer IEA Caenorhabditis elegans 57288 R-CEL-9854415 https://reactome.org/PathwayBrowser/#/R-CEL-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Caenorhabditis elegans 57288 R-CEL-9861667 https://reactome.org/PathwayBrowser/#/R-CEL-9861667 DLAT trimer transfers acetyl to CoA IEA Caenorhabditis elegans 57288 R-CFA-1678660 https://reactome.org/PathwayBrowser/#/R-CFA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Canis familiaris 57288 R-CFA-191323 https://reactome.org/PathwayBrowser/#/R-CFA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Canis familiaris 57288 R-CFA-200555 https://reactome.org/PathwayBrowser/#/R-CFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Canis familiaris 57288 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 57288 R-CFA-2066788 https://reactome.org/PathwayBrowser/#/R-CFA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Canis familiaris 57288 R-CFA-2090085 https://reactome.org/PathwayBrowser/#/R-CFA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Canis familiaris 57288 R-CFA-209792 https://reactome.org/PathwayBrowser/#/R-CFA-209792 N-acetylation of serotonin IEA Canis familiaris 57288 R-CFA-2468039 https://reactome.org/PathwayBrowser/#/R-CFA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Canis familiaris 57288 R-CFA-2473152 https://reactome.org/PathwayBrowser/#/R-CFA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Canis familiaris 57288 R-CFA-2545203 https://reactome.org/PathwayBrowser/#/R-CFA-2545203 Deacetylation of cleaved cohesin IEA Canis familiaris 57288 R-CFA-2545253 https://reactome.org/PathwayBrowser/#/R-CFA-2545253 Deacetylation of cohesin IEA Canis familiaris 57288 R-CFA-264622 https://reactome.org/PathwayBrowser/#/R-CFA-264622 Cho is acetylated to AcCho by CHAT IEA Canis familiaris 57288 R-CFA-3318413 https://reactome.org/PathwayBrowser/#/R-CFA-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Canis familiaris 57288 R-CFA-3318415 https://reactome.org/PathwayBrowser/#/R-CFA-3318415 ATF2 acetylates histone H2B, H4 IEA Canis familiaris 57288 R-CFA-3318486 https://reactome.org/PathwayBrowser/#/R-CFA-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Canis familiaris 57288 R-CFA-3321805 https://reactome.org/PathwayBrowser/#/R-CFA-3321805 NSL acetylates histone H4 IEA Canis familiaris 57288 R-CFA-3321883 https://reactome.org/PathwayBrowser/#/R-CFA-3321883 MSL acetylates histone H4 IEA Canis familiaris 57288 R-CFA-3371554 https://reactome.org/PathwayBrowser/#/R-CFA-3371554 HSF1 acetylation at Lys80 IEA Canis familiaris 57288 R-CFA-351207 https://reactome.org/PathwayBrowser/#/R-CFA-351207 Spermine => N-acetylated spermine IEA Canis familiaris 57288 R-CFA-351208 https://reactome.org/PathwayBrowser/#/R-CFA-351208 Spermidine => N-acetylated spermidine IEA Canis familiaris 57288 R-CFA-3662335 https://reactome.org/PathwayBrowser/#/R-CFA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Canis familiaris 57288 R-CFA-390250 https://reactome.org/PathwayBrowser/#/R-CFA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Canis familiaris 57288 R-CFA-390291 https://reactome.org/PathwayBrowser/#/R-CFA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Canis familiaris 57288 R-CFA-390304 https://reactome.org/PathwayBrowser/#/R-CFA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Canis familiaris 57288 R-CFA-449734 https://reactome.org/PathwayBrowser/#/R-CFA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Canis familiaris 57288 R-CFA-449911 https://reactome.org/PathwayBrowser/#/R-CFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Canis familiaris 57288 R-CFA-5250938 https://reactome.org/PathwayBrowser/#/R-CFA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Canis familiaris 57288 R-CFA-5618328 https://reactome.org/PathwayBrowser/#/R-CFA-5618328 ATAT acetylates microtubules IEA Canis familiaris 57288 R-CFA-5618331 https://reactome.org/PathwayBrowser/#/R-CFA-5618331 HDAC6 deacetylates microtubules IEA Canis familiaris 57288 R-CFA-5628871 https://reactome.org/PathwayBrowser/#/R-CFA-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Canis familiaris 57288 R-CFA-5660660 https://reactome.org/PathwayBrowser/#/R-CFA-5660660 p300 acetylates RELA subunit IEA Canis familiaris 57288 R-CFA-5682044 https://reactome.org/PathwayBrowser/#/R-CFA-5682044 KAT5 acetylates ATM at DNA DSBs IEA Canis familiaris 57288 R-CFA-6788597 https://reactome.org/PathwayBrowser/#/R-CFA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Canis familiaris 57288 R-CFA-6792712 https://reactome.org/PathwayBrowser/#/R-CFA-6792712 KAT5 acetylates ATM at shortened telomeres IEA Canis familiaris 57288 R-CFA-6805638 https://reactome.org/PathwayBrowser/#/R-CFA-6805638 KAT6A acetylates TP53 IEA Canis familiaris 57288 R-CFA-6811508 https://reactome.org/PathwayBrowser/#/R-CFA-6811508 ING2-bound EP300 acetylates TP53 IEA Canis familiaris 57288 R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 57288 R-CFA-70542 https://reactome.org/PathwayBrowser/#/R-CFA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Canis familiaris 57288 R-CFA-70844 https://reactome.org/PathwayBrowser/#/R-CFA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Canis familiaris 57288 R-CFA-70975 https://reactome.org/PathwayBrowser/#/R-CFA-70975 CS acetylates OA to citrate IEA Canis familiaris 57288 R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 57288 R-CFA-71735 https://reactome.org/PathwayBrowser/#/R-CFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Canis familiaris 57288 R-CFA-727759 https://reactome.org/PathwayBrowser/#/R-CFA-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Canis familiaris 57288 R-CFA-73916 https://reactome.org/PathwayBrowser/#/R-CFA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Canis familiaris 57288 R-CFA-73918 https://reactome.org/PathwayBrowser/#/R-CFA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Canis familiaris 57288 R-CFA-74180 https://reactome.org/PathwayBrowser/#/R-CFA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Canis familiaris 57288 R-CFA-74181 https://reactome.org/PathwayBrowser/#/R-CFA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Canis familiaris 57288 R-CFA-75848 https://reactome.org/PathwayBrowser/#/R-CFA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Canis familiaris 57288 R-CFA-75851 https://reactome.org/PathwayBrowser/#/R-CFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 57288 R-CFA-75872 https://reactome.org/PathwayBrowser/#/R-CFA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Canis familiaris 57288 R-CFA-77271 https://reactome.org/PathwayBrowser/#/R-CFA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Canis familiaris 57288 R-CFA-77304 https://reactome.org/PathwayBrowser/#/R-CFA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Canis familiaris 57288 R-CFA-77309 https://reactome.org/PathwayBrowser/#/R-CFA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Canis familiaris 57288 R-CFA-77321 https://reactome.org/PathwayBrowser/#/R-CFA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Canis familiaris 57288 R-CFA-77329 https://reactome.org/PathwayBrowser/#/R-CFA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Canis familiaris 57288 R-CFA-77340 https://reactome.org/PathwayBrowser/#/R-CFA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Canis familiaris 57288 R-CFA-8848215 https://reactome.org/PathwayBrowser/#/R-CFA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Canis familiaris 57288 R-CFA-8874745 https://reactome.org/PathwayBrowser/#/R-CFA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Canis familiaris 57288 R-CFA-8875071 https://reactome.org/PathwayBrowser/#/R-CFA-8875071 ACSS3 ligates CoA to CH3COO- IEA Canis familiaris 57288 R-CFA-8876889 https://reactome.org/PathwayBrowser/#/R-CFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 57288 R-CFA-8951966 https://reactome.org/PathwayBrowser/#/R-CFA-8951966 EP300 acetylates RUNX3 IEA Canis familiaris 57288 R-CFA-8954468 https://reactome.org/PathwayBrowser/#/R-CFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Canis familiaris 57288 R-CFA-9620515 https://reactome.org/PathwayBrowser/#/R-CFA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Canis familiaris 57288 R-CFA-9701531 https://reactome.org/PathwayBrowser/#/R-CFA-9701531 p-Y705,S727 STAT3 is acetylated IEA Canis familiaris 57288 R-CFA-9760081 https://reactome.org/PathwayBrowser/#/R-CFA-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Canis familiaris 57288 R-CFA-977317 https://reactome.org/PathwayBrowser/#/R-CFA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Canis familiaris 57288 R-CFA-9825747 https://reactome.org/PathwayBrowser/#/R-CFA-9825747 CREBBP acetylates HINT1 dimer IEA Canis familiaris 57288 R-CFA-9854415 https://reactome.org/PathwayBrowser/#/R-CFA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Canis familiaris 57288 R-CFA-9861667 https://reactome.org/PathwayBrowser/#/R-CFA-9861667 DLAT trimer transfers acetyl to CoA IEA Canis familiaris 57288 R-DDI-1678660 https://reactome.org/PathwayBrowser/#/R-DDI-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Dictyostelium discoideum 57288 R-DDI-191323 https://reactome.org/PathwayBrowser/#/R-DDI-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Dictyostelium discoideum 57288 R-DDI-200555 https://reactome.org/PathwayBrowser/#/R-DDI-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Dictyostelium discoideum 57288 R-DDI-2066788 https://reactome.org/PathwayBrowser/#/R-DDI-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Dictyostelium discoideum 57288 R-DDI-2090085 https://reactome.org/PathwayBrowser/#/R-DDI-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Dictyostelium discoideum 57288 R-DDI-2468039 https://reactome.org/PathwayBrowser/#/R-DDI-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Dictyostelium discoideum 57288 R-DDI-2473152 https://reactome.org/PathwayBrowser/#/R-DDI-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Dictyostelium discoideum 57288 R-DDI-2545253 https://reactome.org/PathwayBrowser/#/R-DDI-2545253 Deacetylation of cohesin IEA Dictyostelium discoideum 57288 R-DDI-3318413 https://reactome.org/PathwayBrowser/#/R-DDI-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Dictyostelium discoideum 57288 R-DDI-3318486 https://reactome.org/PathwayBrowser/#/R-DDI-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Dictyostelium discoideum 57288 R-DDI-351207 https://reactome.org/PathwayBrowser/#/R-DDI-351207 Spermine => N-acetylated spermine IEA Dictyostelium discoideum 57288 R-DDI-351208 https://reactome.org/PathwayBrowser/#/R-DDI-351208 Spermidine => N-acetylated spermidine IEA Dictyostelium discoideum 57288 R-DDI-3662318 https://reactome.org/PathwayBrowser/#/R-DDI-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Dictyostelium discoideum 57288 R-DDI-390250 https://reactome.org/PathwayBrowser/#/R-DDI-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Dictyostelium discoideum 57288 R-DDI-449734 https://reactome.org/PathwayBrowser/#/R-DDI-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Dictyostelium discoideum 57288 R-DDI-449911 https://reactome.org/PathwayBrowser/#/R-DDI-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Dictyostelium discoideum 57288 R-DDI-5618331 https://reactome.org/PathwayBrowser/#/R-DDI-5618331 HDAC6 deacetylates microtubules IEA Dictyostelium discoideum 57288 R-DDI-5682044 https://reactome.org/PathwayBrowser/#/R-DDI-5682044 KAT5 acetylates ATM at DNA DSBs IEA Dictyostelium discoideum 57288 R-DDI-6788597 https://reactome.org/PathwayBrowser/#/R-DDI-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Dictyostelium discoideum 57288 R-DDI-6792712 https://reactome.org/PathwayBrowser/#/R-DDI-6792712 KAT5 acetylates ATM at shortened telomeres IEA Dictyostelium discoideum 57288 R-DDI-70542 https://reactome.org/PathwayBrowser/#/R-DDI-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Dictyostelium discoideum 57288 R-DDI-70844 https://reactome.org/PathwayBrowser/#/R-DDI-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Dictyostelium discoideum 57288 R-DDI-70975 https://reactome.org/PathwayBrowser/#/R-DDI-70975 CS acetylates OA to citrate IEA Dictyostelium discoideum 57288 R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 57288 R-DDI-71735 https://reactome.org/PathwayBrowser/#/R-DDI-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Dictyostelium discoideum 57288 R-DDI-727759 https://reactome.org/PathwayBrowser/#/R-DDI-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Dictyostelium discoideum 57288 R-DDI-73916 https://reactome.org/PathwayBrowser/#/R-DDI-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Dictyostelium discoideum 57288 R-DDI-73918 https://reactome.org/PathwayBrowser/#/R-DDI-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Dictyostelium discoideum 57288 R-DDI-74180 https://reactome.org/PathwayBrowser/#/R-DDI-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Dictyostelium discoideum 57288 R-DDI-74181 https://reactome.org/PathwayBrowser/#/R-DDI-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Dictyostelium discoideum 57288 R-DDI-75848 https://reactome.org/PathwayBrowser/#/R-DDI-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Dictyostelium discoideum 57288 R-DDI-75851 https://reactome.org/PathwayBrowser/#/R-DDI-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 57288 R-DDI-75872 https://reactome.org/PathwayBrowser/#/R-DDI-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Dictyostelium discoideum 57288 R-DDI-8848215 https://reactome.org/PathwayBrowser/#/R-DDI-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Dictyostelium discoideum 57288 R-DDI-8875071 https://reactome.org/PathwayBrowser/#/R-DDI-8875071 ACSS3 ligates CoA to CH3COO- IEA Dictyostelium discoideum 57288 R-DDI-8876889 https://reactome.org/PathwayBrowser/#/R-DDI-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 57288 R-DDI-8954468 https://reactome.org/PathwayBrowser/#/R-DDI-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Dictyostelium discoideum 57288 R-DDI-977317 https://reactome.org/PathwayBrowser/#/R-DDI-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Dictyostelium discoideum 57288 R-DDI-9861667 https://reactome.org/PathwayBrowser/#/R-DDI-9861667 DLAT trimer transfers acetyl to CoA IEA Dictyostelium discoideum 57288 R-DME-1678660 https://reactome.org/PathwayBrowser/#/R-DME-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Drosophila melanogaster 57288 R-DME-191323 https://reactome.org/PathwayBrowser/#/R-DME-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Drosophila melanogaster 57288 R-DME-200555 https://reactome.org/PathwayBrowser/#/R-DME-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Drosophila melanogaster 57288 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 57288 R-DME-2090085 https://reactome.org/PathwayBrowser/#/R-DME-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Drosophila melanogaster 57288 R-DME-2468039 https://reactome.org/PathwayBrowser/#/R-DME-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Drosophila melanogaster 57288 R-DME-2473152 https://reactome.org/PathwayBrowser/#/R-DME-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Drosophila melanogaster 57288 R-DME-264622 https://reactome.org/PathwayBrowser/#/R-DME-264622 Cho is acetylated to AcCho by CHAT IEA Drosophila melanogaster 57288 R-DME-3318415 https://reactome.org/PathwayBrowser/#/R-DME-3318415 ATF2 acetylates histone H2B, H4 IEA Drosophila melanogaster 57288 R-DME-3321805 https://reactome.org/PathwayBrowser/#/R-DME-3321805 NSL acetylates histone H4 IEA Drosophila melanogaster 57288 R-DME-3321883 https://reactome.org/PathwayBrowser/#/R-DME-3321883 MSL acetylates histone H4 IEA Drosophila melanogaster 57288 R-DME-351207 https://reactome.org/PathwayBrowser/#/R-DME-351207 Spermine => N-acetylated spermine IEA Drosophila melanogaster 57288 R-DME-351208 https://reactome.org/PathwayBrowser/#/R-DME-351208 Spermidine => N-acetylated spermidine IEA Drosophila melanogaster 57288 R-DME-3662318 https://reactome.org/PathwayBrowser/#/R-DME-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Drosophila melanogaster 57288 R-DME-3662335 https://reactome.org/PathwayBrowser/#/R-DME-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Drosophila melanogaster 57288 R-DME-390291 https://reactome.org/PathwayBrowser/#/R-DME-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Drosophila melanogaster 57288 R-DME-449734 https://reactome.org/PathwayBrowser/#/R-DME-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Drosophila melanogaster 57288 R-DME-5628871 https://reactome.org/PathwayBrowser/#/R-DME-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Drosophila melanogaster 57288 R-DME-5660660 https://reactome.org/PathwayBrowser/#/R-DME-5660660 p300 acetylates RELA subunit IEA Drosophila melanogaster 57288 R-DME-5682044 https://reactome.org/PathwayBrowser/#/R-DME-5682044 KAT5 acetylates ATM at DNA DSBs IEA Drosophila melanogaster 57288 R-DME-6788597 https://reactome.org/PathwayBrowser/#/R-DME-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Drosophila melanogaster 57288 R-DME-6792712 https://reactome.org/PathwayBrowser/#/R-DME-6792712 KAT5 acetylates ATM at shortened telomeres IEA Drosophila melanogaster 57288 R-DME-6805638 https://reactome.org/PathwayBrowser/#/R-DME-6805638 KAT6A acetylates TP53 IEA Drosophila melanogaster 57288 R-DME-6811508 https://reactome.org/PathwayBrowser/#/R-DME-6811508 ING2-bound EP300 acetylates TP53 IEA Drosophila melanogaster 57288 R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 57288 R-DME-70844 https://reactome.org/PathwayBrowser/#/R-DME-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Drosophila melanogaster 57288 R-DME-70975 https://reactome.org/PathwayBrowser/#/R-DME-70975 CS acetylates OA to citrate IEA Drosophila melanogaster 57288 R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 57288 R-DME-71735 https://reactome.org/PathwayBrowser/#/R-DME-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Drosophila melanogaster 57288 R-DME-727759 https://reactome.org/PathwayBrowser/#/R-DME-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Drosophila melanogaster 57288 R-DME-73916 https://reactome.org/PathwayBrowser/#/R-DME-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Drosophila melanogaster 57288 R-DME-73918 https://reactome.org/PathwayBrowser/#/R-DME-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Drosophila melanogaster 57288 R-DME-74180 https://reactome.org/PathwayBrowser/#/R-DME-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Drosophila melanogaster 57288 R-DME-74181 https://reactome.org/PathwayBrowser/#/R-DME-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Drosophila melanogaster 57288 R-DME-75848 https://reactome.org/PathwayBrowser/#/R-DME-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Drosophila melanogaster 57288 R-DME-75851 https://reactome.org/PathwayBrowser/#/R-DME-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 57288 R-DME-75872 https://reactome.org/PathwayBrowser/#/R-DME-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Drosophila melanogaster 57288 R-DME-77271 https://reactome.org/PathwayBrowser/#/R-DME-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Drosophila melanogaster 57288 R-DME-77304 https://reactome.org/PathwayBrowser/#/R-DME-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Drosophila melanogaster 57288 R-DME-77309 https://reactome.org/PathwayBrowser/#/R-DME-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Drosophila melanogaster 57288 R-DME-77321 https://reactome.org/PathwayBrowser/#/R-DME-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Drosophila melanogaster 57288 R-DME-77329 https://reactome.org/PathwayBrowser/#/R-DME-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Drosophila melanogaster 57288 R-DME-77340 https://reactome.org/PathwayBrowser/#/R-DME-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Drosophila melanogaster 57288 R-DME-8848215 https://reactome.org/PathwayBrowser/#/R-DME-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Drosophila melanogaster 57288 R-DME-8874745 https://reactome.org/PathwayBrowser/#/R-DME-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Drosophila melanogaster 57288 R-DME-8875071 https://reactome.org/PathwayBrowser/#/R-DME-8875071 ACSS3 ligates CoA to CH3COO- IEA Drosophila melanogaster 57288 R-DME-8876889 https://reactome.org/PathwayBrowser/#/R-DME-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 57288 R-DME-8951966 https://reactome.org/PathwayBrowser/#/R-DME-8951966 EP300 acetylates RUNX3 IEA Drosophila melanogaster 57288 R-DME-9620515 https://reactome.org/PathwayBrowser/#/R-DME-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Drosophila melanogaster 57288 R-DME-9701531 https://reactome.org/PathwayBrowser/#/R-DME-9701531 p-Y705,S727 STAT3 is acetylated IEA Drosophila melanogaster 57288 R-DME-9760081 https://reactome.org/PathwayBrowser/#/R-DME-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Drosophila melanogaster 57288 R-DME-9825747 https://reactome.org/PathwayBrowser/#/R-DME-9825747 CREBBP acetylates HINT1 dimer IEA Drosophila melanogaster 57288 R-DME-9861667 https://reactome.org/PathwayBrowser/#/R-DME-9861667 DLAT trimer transfers acetyl to CoA IEA Drosophila melanogaster 57288 R-DRE-158832 https://reactome.org/PathwayBrowser/#/R-DRE-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Danio rerio 57288 R-DRE-174959 https://reactome.org/PathwayBrowser/#/R-DRE-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Danio rerio 57288 R-DRE-2066788 https://reactome.org/PathwayBrowser/#/R-DRE-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Danio rerio 57288 R-DRE-209792 https://reactome.org/PathwayBrowser/#/R-DRE-209792 N-acetylation of serotonin IEA Danio rerio 57288 R-DRE-2468039 https://reactome.org/PathwayBrowser/#/R-DRE-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Danio rerio 57288 R-DRE-2473152 https://reactome.org/PathwayBrowser/#/R-DRE-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Danio rerio 57288 R-DRE-2545253 https://reactome.org/PathwayBrowser/#/R-DRE-2545253 Deacetylation of cohesin IEA Danio rerio 57288 R-DRE-264622 https://reactome.org/PathwayBrowser/#/R-DRE-264622 Cho is acetylated to AcCho by CHAT IEA Danio rerio 57288 R-DRE-351207 https://reactome.org/PathwayBrowser/#/R-DRE-351207 Spermine => N-acetylated spermine IEA Danio rerio 57288 R-DRE-351208 https://reactome.org/PathwayBrowser/#/R-DRE-351208 Spermidine => N-acetylated spermidine IEA Danio rerio 57288 R-DRE-3662318 https://reactome.org/PathwayBrowser/#/R-DRE-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Danio rerio 57288 R-DRE-390250 https://reactome.org/PathwayBrowser/#/R-DRE-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Danio rerio 57288 R-DRE-390291 https://reactome.org/PathwayBrowser/#/R-DRE-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Danio rerio 57288 R-DRE-390304 https://reactome.org/PathwayBrowser/#/R-DRE-390304 acetyl-CoA + H2O => acetate + CoASH IEA Danio rerio 57288 R-DRE-449734 https://reactome.org/PathwayBrowser/#/R-DRE-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Danio rerio 57288 R-DRE-6788597 https://reactome.org/PathwayBrowser/#/R-DRE-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Danio rerio 57288 R-DRE-6805638 https://reactome.org/PathwayBrowser/#/R-DRE-6805638 KAT6A acetylates TP53 IEA Danio rerio 57288 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 57288 R-DRE-70542 https://reactome.org/PathwayBrowser/#/R-DRE-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Danio rerio 57288 R-DRE-70844 https://reactome.org/PathwayBrowser/#/R-DRE-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Danio rerio 57288 R-DRE-70975 https://reactome.org/PathwayBrowser/#/R-DRE-70975 CS acetylates OA to citrate IEA Danio rerio 57288 R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 57288 R-DRE-727759 https://reactome.org/PathwayBrowser/#/R-DRE-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Danio rerio 57288 R-DRE-73916 https://reactome.org/PathwayBrowser/#/R-DRE-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Danio rerio 57288 R-DRE-74180 https://reactome.org/PathwayBrowser/#/R-DRE-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Danio rerio 57288 R-DRE-74181 https://reactome.org/PathwayBrowser/#/R-DRE-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Danio rerio 57288 R-DRE-75848 https://reactome.org/PathwayBrowser/#/R-DRE-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Danio rerio 57288 R-DRE-75872 https://reactome.org/PathwayBrowser/#/R-DRE-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Danio rerio 57288 R-DRE-77271 https://reactome.org/PathwayBrowser/#/R-DRE-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Danio rerio 57288 R-DRE-77304 https://reactome.org/PathwayBrowser/#/R-DRE-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Danio rerio 57288 R-DRE-77309 https://reactome.org/PathwayBrowser/#/R-DRE-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Danio rerio 57288 R-DRE-77321 https://reactome.org/PathwayBrowser/#/R-DRE-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Danio rerio 57288 R-DRE-77329 https://reactome.org/PathwayBrowser/#/R-DRE-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Danio rerio 57288 R-DRE-77340 https://reactome.org/PathwayBrowser/#/R-DRE-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Danio rerio 57288 R-DRE-8848215 https://reactome.org/PathwayBrowser/#/R-DRE-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Danio rerio 57288 R-DRE-8874745 https://reactome.org/PathwayBrowser/#/R-DRE-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Danio rerio 57288 R-DRE-8954468 https://reactome.org/PathwayBrowser/#/R-DRE-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Danio rerio 57288 R-DRE-9620515 https://reactome.org/PathwayBrowser/#/R-DRE-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Danio rerio 57288 R-DRE-9753676 https://reactome.org/PathwayBrowser/#/R-DRE-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Danio rerio 57288 R-DRE-977317 https://reactome.org/PathwayBrowser/#/R-DRE-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Danio rerio 57288 R-DRE-9854415 https://reactome.org/PathwayBrowser/#/R-DRE-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Danio rerio 57288 R-GGA-158832 https://reactome.org/PathwayBrowser/#/R-GGA-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Gallus gallus 57288 R-GGA-1678660 https://reactome.org/PathwayBrowser/#/R-GGA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Gallus gallus 57288 R-GGA-174959 https://reactome.org/PathwayBrowser/#/R-GGA-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Gallus gallus 57288 R-GGA-191323 https://reactome.org/PathwayBrowser/#/R-GGA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Gallus gallus 57288 R-GGA-200555 https://reactome.org/PathwayBrowser/#/R-GGA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Gallus gallus 57288 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 57288 R-GGA-2066788 https://reactome.org/PathwayBrowser/#/R-GGA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Gallus gallus 57288 R-GGA-2090085 https://reactome.org/PathwayBrowser/#/R-GGA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Gallus gallus 57288 R-GGA-209792 https://reactome.org/PathwayBrowser/#/R-GGA-209792 N-acetylation of serotonin IEA Gallus gallus 57288 R-GGA-2468039 https://reactome.org/PathwayBrowser/#/R-GGA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus 57288 R-GGA-2473152 https://reactome.org/PathwayBrowser/#/R-GGA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus 57288 R-GGA-2545203 https://reactome.org/PathwayBrowser/#/R-GGA-2545203 Deacetylation of cleaved cohesin IEA Gallus gallus 57288 R-GGA-2545253 https://reactome.org/PathwayBrowser/#/R-GGA-2545253 Deacetylation of cohesin IEA Gallus gallus 57288 R-GGA-264622 https://reactome.org/PathwayBrowser/#/R-GGA-264622 Cho is acetylated to AcCho by CHAT IEA Gallus gallus 57288 R-GGA-3318415 https://reactome.org/PathwayBrowser/#/R-GGA-3318415 ATF2 acetylates histone H2B, H4 IEA Gallus gallus 57288 R-GGA-3321883 https://reactome.org/PathwayBrowser/#/R-GGA-3321883 MSL acetylates histone H4 IEA Gallus gallus 57288 R-GGA-3371554 https://reactome.org/PathwayBrowser/#/R-GGA-3371554 HSF1 acetylation at Lys80 IEA Gallus gallus 57288 R-GGA-351207 https://reactome.org/PathwayBrowser/#/R-GGA-351207 Spermine => N-acetylated spermine IEA Gallus gallus 57288 R-GGA-351208 https://reactome.org/PathwayBrowser/#/R-GGA-351208 Spermidine => N-acetylated spermidine IEA Gallus gallus 57288 R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 57288 R-GGA-3662318 https://reactome.org/PathwayBrowser/#/R-GGA-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Gallus gallus 57288 R-GGA-3662335 https://reactome.org/PathwayBrowser/#/R-GGA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Gallus gallus 57288 R-GGA-373006 https://reactome.org/PathwayBrowser/#/R-GGA-373006 acetyl-CoA + H2O + oxaloacetate => citrate + CoA TAS Gallus gallus 57288 R-GGA-373177 https://reactome.org/PathwayBrowser/#/R-GGA-373177 pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ TAS Gallus gallus 57288 R-GGA-390250 https://reactome.org/PathwayBrowser/#/R-GGA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Gallus gallus 57288 R-GGA-390291 https://reactome.org/PathwayBrowser/#/R-GGA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Gallus gallus 57288 R-GGA-390304 https://reactome.org/PathwayBrowser/#/R-GGA-390304 acetyl-CoA + H2O => acetate + CoASH IEA Gallus gallus 57288 R-GGA-449734 https://reactome.org/PathwayBrowser/#/R-GGA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Gallus gallus 57288 R-GGA-449911 https://reactome.org/PathwayBrowser/#/R-GGA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Gallus gallus 57288 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus 57288 R-GGA-5660660 https://reactome.org/PathwayBrowser/#/R-GGA-5660660 p300 acetylates RELA subunit IEA Gallus gallus 57288 R-GGA-5682044 https://reactome.org/PathwayBrowser/#/R-GGA-5682044 KAT5 acetylates ATM at DNA DSBs IEA Gallus gallus 57288 R-GGA-6788597 https://reactome.org/PathwayBrowser/#/R-GGA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Gallus gallus 57288 R-GGA-6792712 https://reactome.org/PathwayBrowser/#/R-GGA-6792712 KAT5 acetylates ATM at shortened telomeres IEA Gallus gallus 57288 R-GGA-70844 https://reactome.org/PathwayBrowser/#/R-GGA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Gallus gallus 57288 R-GGA-70975 https://reactome.org/PathwayBrowser/#/R-GGA-70975 CS acetylates OA to citrate IEA Gallus gallus 57288 R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 57288 R-GGA-71735 https://reactome.org/PathwayBrowser/#/R-GGA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Gallus gallus 57288 R-GGA-727759 https://reactome.org/PathwayBrowser/#/R-GGA-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Gallus gallus 57288 R-GGA-73916 https://reactome.org/PathwayBrowser/#/R-GGA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Gallus gallus 57288 R-GGA-73918 https://reactome.org/PathwayBrowser/#/R-GGA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Gallus gallus 57288 R-GGA-74180 https://reactome.org/PathwayBrowser/#/R-GGA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Gallus gallus 57288 R-GGA-74181 https://reactome.org/PathwayBrowser/#/R-GGA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Gallus gallus 57288 R-GGA-75848 https://reactome.org/PathwayBrowser/#/R-GGA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Gallus gallus 57288 R-GGA-75851 https://reactome.org/PathwayBrowser/#/R-GGA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Gallus gallus 57288 R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Gallus gallus 57288 R-GGA-77271 https://reactome.org/PathwayBrowser/#/R-GGA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Gallus gallus 57288 R-GGA-77304 https://reactome.org/PathwayBrowser/#/R-GGA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Gallus gallus 57288 R-GGA-77309 https://reactome.org/PathwayBrowser/#/R-GGA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Gallus gallus 57288 R-GGA-77321 https://reactome.org/PathwayBrowser/#/R-GGA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Gallus gallus 57288 R-GGA-77329 https://reactome.org/PathwayBrowser/#/R-GGA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Gallus gallus 57288 R-GGA-77340 https://reactome.org/PathwayBrowser/#/R-GGA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Gallus gallus 57288 R-GGA-8848215 https://reactome.org/PathwayBrowser/#/R-GGA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Gallus gallus 57288 R-GGA-8874745 https://reactome.org/PathwayBrowser/#/R-GGA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Gallus gallus 57288 R-GGA-8875071 https://reactome.org/PathwayBrowser/#/R-GGA-8875071 ACSS3 ligates CoA to CH3COO- IEA Gallus gallus 57288 R-GGA-8951966 https://reactome.org/PathwayBrowser/#/R-GGA-8951966 EP300 acetylates RUNX3 IEA Gallus gallus 57288 R-GGA-8954468 https://reactome.org/PathwayBrowser/#/R-GGA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Gallus gallus 57288 R-GGA-9620515 https://reactome.org/PathwayBrowser/#/R-GGA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Gallus gallus 57288 R-GGA-9701531 https://reactome.org/PathwayBrowser/#/R-GGA-9701531 p-Y705,S727 STAT3 is acetylated IEA Gallus gallus 57288 R-GGA-9753676 https://reactome.org/PathwayBrowser/#/R-GGA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Gallus gallus 57288 R-GGA-9760081 https://reactome.org/PathwayBrowser/#/R-GGA-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Gallus gallus 57288 R-GGA-977317 https://reactome.org/PathwayBrowser/#/R-GGA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Gallus gallus 57288 R-GGA-9825747 https://reactome.org/PathwayBrowser/#/R-GGA-9825747 CREBBP acetylates HINT1 dimer IEA Gallus gallus 57288 R-GGA-9854415 https://reactome.org/PathwayBrowser/#/R-GGA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Gallus gallus 57288 R-GGA-9861667 https://reactome.org/PathwayBrowser/#/R-GGA-9861667 DLAT trimer transfers acetyl to CoA IEA Gallus gallus 57288 R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 57288 R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 57288 R-HSA-158832 https://reactome.org/PathwayBrowser/#/R-HSA-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 TAS Homo sapiens 57288 R-HSA-1678660 https://reactome.org/PathwayBrowser/#/R-HSA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) TAS Homo sapiens 57288 R-HSA-174959 https://reactome.org/PathwayBrowser/#/R-HSA-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 TAS Homo sapiens 57288 R-HSA-191323 https://reactome.org/PathwayBrowser/#/R-HSA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA TAS Homo sapiens 57288 R-HSA-200555 https://reactome.org/PathwayBrowser/#/R-HSA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate TAS Homo sapiens 57288 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 57288 R-HSA-2066788 https://reactome.org/PathwayBrowser/#/R-HSA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase TAS Homo sapiens 57288 R-HSA-2090085 https://reactome.org/PathwayBrowser/#/R-HSA-2090085 HGSNAT oligomer acetylates Heparan chain(1) TAS Homo sapiens 57288 R-HSA-209792 https://reactome.org/PathwayBrowser/#/R-HSA-209792 N-acetylation of serotonin TAS Homo sapiens 57288 R-HSA-2263492 https://reactome.org/PathwayBrowser/#/R-HSA-2263492 Defective HGSNAT does not acetylate Heparan chain(1) TAS Homo sapiens 57288 R-HSA-2468039 https://reactome.org/PathwayBrowser/#/R-HSA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 TAS Homo sapiens 57288 R-HSA-2473152 https://reactome.org/PathwayBrowser/#/R-HSA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 TAS Homo sapiens 57288 R-HSA-2545203 https://reactome.org/PathwayBrowser/#/R-HSA-2545203 Deacetylation of cleaved cohesin TAS Homo sapiens 57288 R-HSA-2545253 https://reactome.org/PathwayBrowser/#/R-HSA-2545253 Deacetylation of cohesin TAS Homo sapiens 57288 R-HSA-264622 https://reactome.org/PathwayBrowser/#/R-HSA-264622 Cho is acetylated to AcCho by CHAT TAS Homo sapiens 57288 R-HSA-3301237 https://reactome.org/PathwayBrowser/#/R-HSA-3301237 KAT2 complexes acetylate histone H3 IEA Homo sapiens 57288 R-HSA-3301345 https://reactome.org/PathwayBrowser/#/R-HSA-3301345 Elongator complex acetylates replicative histone H3, H4 IEA Homo sapiens 57288 R-HSA-3318413 https://reactome.org/PathwayBrowser/#/R-HSA-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 TAS Homo sapiens 57288 R-HSA-3318415 https://reactome.org/PathwayBrowser/#/R-HSA-3318415 ATF2 acetylates histone H2B, H4 TAS Homo sapiens 57288 R-HSA-3318486 https://reactome.org/PathwayBrowser/#/R-HSA-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 TAS Homo sapiens 57288 R-HSA-3321805 https://reactome.org/PathwayBrowser/#/R-HSA-3321805 NSL acetylates histone H4 TAS Homo sapiens 57288 R-HSA-3321883 https://reactome.org/PathwayBrowser/#/R-HSA-3321883 MSL acetylates histone H4 TAS Homo sapiens 57288 R-HSA-3321975 https://reactome.org/PathwayBrowser/#/R-HSA-3321975 NuA4 complex acetylates histone H2A, HIST1H4 IEA Homo sapiens 57288 R-HSA-3371554 https://reactome.org/PathwayBrowser/#/R-HSA-3371554 HSF1 acetylation at Lys80 TAS Homo sapiens 57288 R-HSA-3451147 https://reactome.org/PathwayBrowser/#/R-HSA-3451147 KAT5 HAT complex acetylates TCF4 gene at histone H4 IEA Homo sapiens 57288 R-HSA-351207 https://reactome.org/PathwayBrowser/#/R-HSA-351207 Spermine => N-acetylated spermine TAS Homo sapiens 57288 R-HSA-351208 https://reactome.org/PathwayBrowser/#/R-HSA-351208 Spermidine => N-acetylated spermidine TAS Homo sapiens 57288 R-HSA-3662318 https://reactome.org/PathwayBrowser/#/R-HSA-3662318 Type B histone acetlytransferase complex acetylates histone H4 TAS Homo sapiens 57288 R-HSA-3662335 https://reactome.org/PathwayBrowser/#/R-HSA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 TAS Homo sapiens 57288 R-HSA-3697008 https://reactome.org/PathwayBrowser/#/R-HSA-3697008 CREBBP acetylates histone H2B, H3, H4 IEA Homo sapiens 57288 R-HSA-3697920 https://reactome.org/PathwayBrowser/#/R-HSA-3697920 CLOCK acetylates lysine-10 of histone H3, H4 IEA Homo sapiens 57288 R-HSA-390250 https://reactome.org/PathwayBrowser/#/R-HSA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA TAS Homo sapiens 57288 R-HSA-390276 https://reactome.org/PathwayBrowser/#/R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA TAS Homo sapiens 57288 R-HSA-390291 https://reactome.org/PathwayBrowser/#/R-HSA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH TAS Homo sapiens 57288 R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA TAS Homo sapiens 57288 R-HSA-390304 https://reactome.org/PathwayBrowser/#/R-HSA-390304 acetyl-CoA + H2O => acetate + CoASH TAS Homo sapiens 57288 R-HSA-449734 https://reactome.org/PathwayBrowser/#/R-HSA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P TAS Homo sapiens 57288 R-HSA-449911 https://reactome.org/PathwayBrowser/#/R-HSA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] TAS Homo sapiens 57288 R-HSA-5144542 https://reactome.org/PathwayBrowser/#/R-HSA-5144542 CLOCK acetylates lysine-15 of histone H3, H4 IEA Homo sapiens 57288 R-HSA-5250938 https://reactome.org/PathwayBrowser/#/R-HSA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 TAS Homo sapiens 57288 R-HSA-5433066 https://reactome.org/PathwayBrowser/#/R-HSA-5433066 Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C TAS Homo sapiens 57288 R-HSA-5618328 https://reactome.org/PathwayBrowser/#/R-HSA-5618328 ATAT acetylates microtubules TAS Homo sapiens 57288 R-HSA-5618331 https://reactome.org/PathwayBrowser/#/R-HSA-5618331 HDAC6 deacetylates microtubules TAS Homo sapiens 57288 R-HSA-5628871 https://reactome.org/PathwayBrowser/#/R-HSA-5628871 BRD7 promotes EP300-mediated acetylation of TP53 TAS Homo sapiens 57288 R-HSA-5649742 https://reactome.org/PathwayBrowser/#/R-HSA-5649742 Defective SLC33A1 does not transport Ac-CoA from cytosol to Golgi lumen TAS Homo sapiens 57288 R-HSA-5660660 https://reactome.org/PathwayBrowser/#/R-HSA-5660660 p300 acetylates RELA subunit TAS Homo sapiens 57288 R-HSA-5682044 https://reactome.org/PathwayBrowser/#/R-HSA-5682044 KAT5 acetylates ATM at DNA DSBs TAS Homo sapiens 57288 R-HSA-5693001 https://reactome.org/PathwayBrowser/#/R-HSA-5693001 NAT8,8B acetylate BACE1 TAS Homo sapiens 57288 R-HSA-6788597 https://reactome.org/PathwayBrowser/#/R-HSA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA TAS Homo sapiens 57288 R-HSA-6790987 https://reactome.org/PathwayBrowser/#/R-HSA-6790987 NAT10 acetylates cytidine-1337 and cytidine-1842 of 18S rRNA yielding 4-acetylcytidine-1377 and 4-acetylcytidine-1842 TAS Homo sapiens 57288 R-HSA-6792712 https://reactome.org/PathwayBrowser/#/R-HSA-6792712 KAT5 acetylates ATM at shortened telomeres TAS Homo sapiens 57288 R-HSA-6798345 https://reactome.org/PathwayBrowser/#/R-HSA-6798345 PXLP-GCAT dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA TAS Homo sapiens 57288 R-HSA-6805638 https://reactome.org/PathwayBrowser/#/R-HSA-6805638 KAT6A acetylates TP53 TAS Homo sapiens 57288 R-HSA-6811508 https://reactome.org/PathwayBrowser/#/R-HSA-6811508 ING2-bound EP300 acetylates TP53 TAS Homo sapiens 57288 R-HSA-6814090 https://reactome.org/PathwayBrowser/#/R-HSA-6814090 NatC acetylates ARFFRP1 IEA Homo sapiens 57288 R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 57288 R-HSA-70542 https://reactome.org/PathwayBrowser/#/R-HSA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA TAS Homo sapiens 57288 R-HSA-70844 https://reactome.org/PathwayBrowser/#/R-HSA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA TAS Homo sapiens 57288 R-HSA-70975 https://reactome.org/PathwayBrowser/#/R-HSA-70975 CS acetylates OA to citrate TAS Homo sapiens 57288 R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 57288 R-HSA-71735 https://reactome.org/PathwayBrowser/#/R-HSA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] TAS Homo sapiens 57288 R-HSA-727759 https://reactome.org/PathwayBrowser/#/R-HSA-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen TAS Homo sapiens 57288 R-HSA-73736 https://reactome.org/PathwayBrowser/#/R-HSA-73736 Acetylation of SL1 IEA Homo sapiens 57288 R-HSA-73916 https://reactome.org/PathwayBrowser/#/R-HSA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA TAS Homo sapiens 57288 R-HSA-73918 https://reactome.org/PathwayBrowser/#/R-HSA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH TAS Homo sapiens 57288 R-HSA-74180 https://reactome.org/PathwayBrowser/#/R-HSA-74180 HMG CoA => acetoacetic acid + acetyl CoA TAS Homo sapiens 57288 R-HSA-74181 https://reactome.org/PathwayBrowser/#/R-HSA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA TAS Homo sapiens 57288 R-HSA-75848 https://reactome.org/PathwayBrowser/#/R-HSA-75848 ACLY tetramer transforms CIT to Ac-CoA TAS Homo sapiens 57288 R-HSA-75851 https://reactome.org/PathwayBrowser/#/R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 57288 R-HSA-75872 https://reactome.org/PathwayBrowser/#/R-HSA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O TAS Homo sapiens 57288 R-HSA-77271 https://reactome.org/PathwayBrowser/#/R-HSA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA TAS Homo sapiens 57288 R-HSA-77304 https://reactome.org/PathwayBrowser/#/R-HSA-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA TAS Homo sapiens 57288 R-HSA-77309 https://reactome.org/PathwayBrowser/#/R-HSA-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA TAS Homo sapiens 57288 R-HSA-77321 https://reactome.org/PathwayBrowser/#/R-HSA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA TAS Homo sapiens 57288 R-HSA-77329 https://reactome.org/PathwayBrowser/#/R-HSA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA TAS Homo sapiens 57288 R-HSA-77340 https://reactome.org/PathwayBrowser/#/R-HSA-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA TAS Homo sapiens 57288 R-HSA-8848215 https://reactome.org/PathwayBrowser/#/R-HSA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA TAS Homo sapiens 57288 R-HSA-8874745 https://reactome.org/PathwayBrowser/#/R-HSA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH TAS Homo sapiens 57288 R-HSA-8875071 https://reactome.org/PathwayBrowser/#/R-HSA-8875071 ACSS3 ligates CoA to CH3COO- TAS Homo sapiens 57288 R-HSA-8876889 https://reactome.org/PathwayBrowser/#/R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 57288 R-HSA-8951966 https://reactome.org/PathwayBrowser/#/R-HSA-8951966 EP300 acetylates RUNX3 TAS Homo sapiens 57288 R-HSA-8954468 https://reactome.org/PathwayBrowser/#/R-HSA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA TAS Homo sapiens 57288 R-HSA-9036056 https://reactome.org/PathwayBrowser/#/R-HSA-9036056 Defective HGSNAT does not acetylate Heparan sulfate chain(3) TAS Homo sapiens 57288 R-HSA-9614810 https://reactome.org/PathwayBrowser/#/R-HSA-9614810 Activation of Latent HCMV Genome TAS Homo sapiens 57288 R-HSA-9617758 https://reactome.org/PathwayBrowser/#/R-HSA-9617758 EP300,CREBBP acetylate FOXO4 IEA Homo sapiens 57288 R-HSA-9620515 https://reactome.org/PathwayBrowser/#/R-HSA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress TAS Homo sapiens 57288 R-HSA-9626945 https://reactome.org/PathwayBrowser/#/R-HSA-9626945 CREBBP acetylates FOXO1 IEA Homo sapiens 57288 R-HSA-9636560 https://reactome.org/PathwayBrowser/#/R-HSA-9636560 Eis acetylates DUSP16 TAS Homo sapiens 57288 R-HSA-9701531 https://reactome.org/PathwayBrowser/#/R-HSA-9701531 p-Y705,S727 STAT3 is acetylated TAS Homo sapiens 57288 R-HSA-9753676 https://reactome.org/PathwayBrowser/#/R-HSA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer TAS Homo sapiens 57288 R-HSA-9756494 https://reactome.org/PathwayBrowser/#/R-HSA-9756494 CREBBP acetylates SARS-CoV-2 N at K375 TAS Homo sapiens 57288 R-HSA-9760081 https://reactome.org/PathwayBrowser/#/R-HSA-9760081 CREBBP, EP300 acetylates NFE2L2 TAS Homo sapiens 57288 R-HSA-977317 https://reactome.org/PathwayBrowser/#/R-HSA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome TAS Homo sapiens 57288 R-HSA-9825747 https://reactome.org/PathwayBrowser/#/R-HSA-9825747 CREBBP acetylates HINT1 dimer TAS Homo sapiens 57288 R-HSA-9854415 https://reactome.org/PathwayBrowser/#/R-HSA-9854415 ACAT1 tetramer acetylates IDH2 dimer TAS Homo sapiens 57288 R-HSA-9861667 https://reactome.org/PathwayBrowser/#/R-HSA-9861667 DLAT trimer transfers acetyl to CoA TAS Homo sapiens 57288 R-MMU-158832 https://reactome.org/PathwayBrowser/#/R-MMU-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Mus musculus 57288 R-MMU-1678660 https://reactome.org/PathwayBrowser/#/R-MMU-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Mus musculus 57288 R-MMU-174959 https://reactome.org/PathwayBrowser/#/R-MMU-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Mus musculus 57288 R-MMU-191323 https://reactome.org/PathwayBrowser/#/R-MMU-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Mus musculus 57288 R-MMU-200555 https://reactome.org/PathwayBrowser/#/R-MMU-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Mus musculus 57288 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 57288 R-MMU-2066788 https://reactome.org/PathwayBrowser/#/R-MMU-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Mus musculus 57288 R-MMU-2090085 https://reactome.org/PathwayBrowser/#/R-MMU-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Mus musculus 57288 R-MMU-209792 https://reactome.org/PathwayBrowser/#/R-MMU-209792 N-acetylation of serotonin IEA Mus musculus 57288 R-MMU-2468039 https://reactome.org/PathwayBrowser/#/R-MMU-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Mus musculus 57288 R-MMU-2473152 https://reactome.org/PathwayBrowser/#/R-MMU-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Mus musculus 57288 R-MMU-2545203 https://reactome.org/PathwayBrowser/#/R-MMU-2545203 Deacetylation of cleaved cohesin IEA Mus musculus 57288 R-MMU-2545253 https://reactome.org/PathwayBrowser/#/R-MMU-2545253 Deacetylation of cohesin IEA Mus musculus 57288 R-MMU-264622 https://reactome.org/PathwayBrowser/#/R-MMU-264622 Cho is acetylated to AcCho by CHAT IEA Mus musculus 57288 R-MMU-3318413 https://reactome.org/PathwayBrowser/#/R-MMU-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Mus musculus 57288 R-MMU-3318415 https://reactome.org/PathwayBrowser/#/R-MMU-3318415 ATF2 acetylates histone H2B, H4 IEA Mus musculus 57288 R-MMU-3318486 https://reactome.org/PathwayBrowser/#/R-MMU-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Mus musculus 57288 R-MMU-3321805 https://reactome.org/PathwayBrowser/#/R-MMU-3321805 NSL acetylates histone H4 IEA Mus musculus 57288 R-MMU-3321883 https://reactome.org/PathwayBrowser/#/R-MMU-3321883 MSL acetylates histone H4 IEA Mus musculus 57288 R-MMU-3371554 https://reactome.org/PathwayBrowser/#/R-MMU-3371554 HSF1 acetylation at Lys80 IEA Mus musculus 57288 R-MMU-351207 https://reactome.org/PathwayBrowser/#/R-MMU-351207 Spermine => N-acetylated spermine IEA Mus musculus 57288 R-MMU-351208 https://reactome.org/PathwayBrowser/#/R-MMU-351208 Spermidine => N-acetylated spermidine IEA Mus musculus 57288 R-MMU-3662318 https://reactome.org/PathwayBrowser/#/R-MMU-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Mus musculus 57288 R-MMU-390250 https://reactome.org/PathwayBrowser/#/R-MMU-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Mus musculus 57288 R-MMU-390291 https://reactome.org/PathwayBrowser/#/R-MMU-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Mus musculus 57288 R-MMU-390304 https://reactome.org/PathwayBrowser/#/R-MMU-390304 acetyl-CoA + H2O => acetate + CoASH IEA Mus musculus 57288 R-MMU-449734 https://reactome.org/PathwayBrowser/#/R-MMU-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Mus musculus 57288 R-MMU-449911 https://reactome.org/PathwayBrowser/#/R-MMU-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Mus musculus 57288 R-MMU-5211235 https://reactome.org/PathwayBrowser/#/R-MMU-5211235 Kat2b (Pcaf) acetylates Taf1b in SL1 Complex TAS Mus musculus 57288 R-MMU-5618328 https://reactome.org/PathwayBrowser/#/R-MMU-5618328 ATAT acetylates microtubules IEA Mus musculus 57288 R-MMU-5618331 https://reactome.org/PathwayBrowser/#/R-MMU-5618331 HDAC6 deacetylates microtubules IEA Mus musculus 57288 R-MMU-5628871 https://reactome.org/PathwayBrowser/#/R-MMU-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Mus musculus 57288 R-MMU-5660660 https://reactome.org/PathwayBrowser/#/R-MMU-5660660 p300 acetylates RELA subunit IEA Mus musculus 57288 R-MMU-5682044 https://reactome.org/PathwayBrowser/#/R-MMU-5682044 KAT5 acetylates ATM at DNA DSBs IEA Mus musculus 57288 R-MMU-6788597 https://reactome.org/PathwayBrowser/#/R-MMU-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Mus musculus 57288 R-MMU-6792712 https://reactome.org/PathwayBrowser/#/R-MMU-6792712 KAT5 acetylates ATM at shortened telomeres IEA Mus musculus 57288 R-MMU-6805638 https://reactome.org/PathwayBrowser/#/R-MMU-6805638 KAT6A acetylates TP53 IEA Mus musculus 57288 R-MMU-6811508 https://reactome.org/PathwayBrowser/#/R-MMU-6811508 ING2-bound EP300 acetylates TP53 IEA Mus musculus 57288 R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 57288 R-MMU-70542 https://reactome.org/PathwayBrowser/#/R-MMU-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Mus musculus 57288 R-MMU-70844 https://reactome.org/PathwayBrowser/#/R-MMU-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Mus musculus 57288 R-MMU-70975 https://reactome.org/PathwayBrowser/#/R-MMU-70975 CS acetylates OA to citrate IEA Mus musculus 57288 R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 57288 R-MMU-71735 https://reactome.org/PathwayBrowser/#/R-MMU-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Mus musculus 57288 R-MMU-727759 https://reactome.org/PathwayBrowser/#/R-MMU-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Mus musculus 57288 R-MMU-73916 https://reactome.org/PathwayBrowser/#/R-MMU-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Mus musculus 57288 R-MMU-73918 https://reactome.org/PathwayBrowser/#/R-MMU-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Mus musculus 57288 R-MMU-74180 https://reactome.org/PathwayBrowser/#/R-MMU-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Mus musculus 57288 R-MMU-74181 https://reactome.org/PathwayBrowser/#/R-MMU-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Mus musculus 57288 R-MMU-75848 https://reactome.org/PathwayBrowser/#/R-MMU-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Mus musculus 57288 R-MMU-75851 https://reactome.org/PathwayBrowser/#/R-MMU-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 57288 R-MMU-75872 https://reactome.org/PathwayBrowser/#/R-MMU-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Mus musculus 57288 R-MMU-77271 https://reactome.org/PathwayBrowser/#/R-MMU-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Mus musculus 57288 R-MMU-77304 https://reactome.org/PathwayBrowser/#/R-MMU-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Mus musculus 57288 R-MMU-77309 https://reactome.org/PathwayBrowser/#/R-MMU-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Mus musculus 57288 R-MMU-77321 https://reactome.org/PathwayBrowser/#/R-MMU-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Mus musculus 57288 R-MMU-77329 https://reactome.org/PathwayBrowser/#/R-MMU-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Mus musculus 57288 R-MMU-77340 https://reactome.org/PathwayBrowser/#/R-MMU-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Mus musculus 57288 R-MMU-8848215 https://reactome.org/PathwayBrowser/#/R-MMU-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Mus musculus 57288 R-MMU-8874745 https://reactome.org/PathwayBrowser/#/R-MMU-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Mus musculus 57288 R-MMU-8875071 https://reactome.org/PathwayBrowser/#/R-MMU-8875071 ACSS3 ligates CoA to CH3COO- IEA Mus musculus 57288 R-MMU-8876889 https://reactome.org/PathwayBrowser/#/R-MMU-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 57288 R-MMU-8951966 https://reactome.org/PathwayBrowser/#/R-MMU-8951966 EP300 acetylates RUNX3 IEA Mus musculus 57288 R-MMU-8954468 https://reactome.org/PathwayBrowser/#/R-MMU-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Mus musculus 57288 R-MMU-9617755 https://reactome.org/PathwayBrowser/#/R-MMU-9617755 Crebbp acetylates Foxo4 TAS Mus musculus 57288 R-MMU-9620515 https://reactome.org/PathwayBrowser/#/R-MMU-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Mus musculus 57288 R-MMU-9701531 https://reactome.org/PathwayBrowser/#/R-MMU-9701531 p-Y705,S727 STAT3 is acetylated IEA Mus musculus 57288 R-MMU-9753676 https://reactome.org/PathwayBrowser/#/R-MMU-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Mus musculus 57288 R-MMU-9760081 https://reactome.org/PathwayBrowser/#/R-MMU-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Mus musculus 57288 R-MMU-977317 https://reactome.org/PathwayBrowser/#/R-MMU-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Mus musculus 57288 R-MMU-9825747 https://reactome.org/PathwayBrowser/#/R-MMU-9825747 CREBBP acetylates HINT1 dimer IEA Mus musculus 57288 R-MMU-9854415 https://reactome.org/PathwayBrowser/#/R-MMU-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Mus musculus 57288 R-MMU-9861667 https://reactome.org/PathwayBrowser/#/R-MMU-9861667 DLAT trimer transfers acetyl to CoA IEA Mus musculus 57288 R-MTU-879248 https://reactome.org/PathwayBrowser/#/R-MTU-879248 desacetylmycothiol is acetylated to mycothiol using acetyl-CoA TAS Mycobacterium tuberculosis 57288 R-MTU-936615 https://reactome.org/PathwayBrowser/#/R-MTU-936615 acetylation of serine TAS Mycobacterium tuberculosis 57288 R-NUL-3451144 https://reactome.org/PathwayBrowser/#/R-NUL-3451144 KAT5 HAT complex acetylates TCF4 (ITF-2) gene at histone H4 TAS Homo sapiens 57288 R-NUL-9617757 https://reactome.org/PathwayBrowser/#/R-NUL-9617757 EP300 acetylates Foxo4 TAS Homo sapiens 57288 R-NUL-9626944 https://reactome.org/PathwayBrowser/#/R-NUL-9626944 CREBBP acetylates Foxo1 TAS Homo sapiens 57288 R-PFA-200555 https://reactome.org/PathwayBrowser/#/R-PFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Plasmodium falciparum 57288 R-PFA-3662318 https://reactome.org/PathwayBrowser/#/R-PFA-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Plasmodium falciparum 57288 R-PFA-449911 https://reactome.org/PathwayBrowser/#/R-PFA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Plasmodium falciparum 57288 R-PFA-5618328 https://reactome.org/PathwayBrowser/#/R-PFA-5618328 ATAT acetylates microtubules IEA Plasmodium falciparum 57288 R-PFA-5618331 https://reactome.org/PathwayBrowser/#/R-PFA-5618331 HDAC6 deacetylates microtubules IEA Plasmodium falciparum 57288 R-PFA-70844 https://reactome.org/PathwayBrowser/#/R-PFA-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Plasmodium falciparum 57288 R-PFA-70975 https://reactome.org/PathwayBrowser/#/R-PFA-70975 CS acetylates OA to citrate IEA Plasmodium falciparum 57288 R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 57288 R-PFA-71735 https://reactome.org/PathwayBrowser/#/R-PFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Plasmodium falciparum 57288 R-PFA-727759 https://reactome.org/PathwayBrowser/#/R-PFA-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Plasmodium falciparum 57288 R-PFA-73916 https://reactome.org/PathwayBrowser/#/R-PFA-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Plasmodium falciparum 57288 R-PFA-74181 https://reactome.org/PathwayBrowser/#/R-PFA-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Plasmodium falciparum 57288 R-PFA-75851 https://reactome.org/PathwayBrowser/#/R-PFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 57288 R-PFA-8848215 https://reactome.org/PathwayBrowser/#/R-PFA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Plasmodium falciparum 57288 R-PFA-8876889 https://reactome.org/PathwayBrowser/#/R-PFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 57288 R-PFA-8954468 https://reactome.org/PathwayBrowser/#/R-PFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Plasmodium falciparum 57288 R-PFA-9854415 https://reactome.org/PathwayBrowser/#/R-PFA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Plasmodium falciparum 57288 R-RNO-158832 https://reactome.org/PathwayBrowser/#/R-RNO-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Rattus norvegicus 57288 R-RNO-1678660 https://reactome.org/PathwayBrowser/#/R-RNO-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Rattus norvegicus 57288 R-RNO-174959 https://reactome.org/PathwayBrowser/#/R-RNO-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Rattus norvegicus 57288 R-RNO-191323 https://reactome.org/PathwayBrowser/#/R-RNO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Rattus norvegicus 57288 R-RNO-200555 https://reactome.org/PathwayBrowser/#/R-RNO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Rattus norvegicus 57288 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 57288 R-RNO-2066788 https://reactome.org/PathwayBrowser/#/R-RNO-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Rattus norvegicus 57288 R-RNO-2090085 https://reactome.org/PathwayBrowser/#/R-RNO-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Rattus norvegicus 57288 R-RNO-209792 https://reactome.org/PathwayBrowser/#/R-RNO-209792 N-acetylation of serotonin IEA Rattus norvegicus 57288 R-RNO-2468039 https://reactome.org/PathwayBrowser/#/R-RNO-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Rattus norvegicus 57288 R-RNO-2473152 https://reactome.org/PathwayBrowser/#/R-RNO-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Rattus norvegicus 57288 R-RNO-2545203 https://reactome.org/PathwayBrowser/#/R-RNO-2545203 Deacetylation of cleaved cohesin IEA Rattus norvegicus 57288 R-RNO-2545253 https://reactome.org/PathwayBrowser/#/R-RNO-2545253 Deacetylation of cohesin IEA Rattus norvegicus 57288 R-RNO-264622 https://reactome.org/PathwayBrowser/#/R-RNO-264622 Cho is acetylated to AcCho by CHAT IEA Rattus norvegicus 57288 R-RNO-3318413 https://reactome.org/PathwayBrowser/#/R-RNO-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Rattus norvegicus 57288 R-RNO-3318415 https://reactome.org/PathwayBrowser/#/R-RNO-3318415 ATF2 acetylates histone H2B, H4 IEA Rattus norvegicus 57288 R-RNO-3318486 https://reactome.org/PathwayBrowser/#/R-RNO-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Rattus norvegicus 57288 R-RNO-3321805 https://reactome.org/PathwayBrowser/#/R-RNO-3321805 NSL acetylates histone H4 IEA Rattus norvegicus 57288 R-RNO-3321883 https://reactome.org/PathwayBrowser/#/R-RNO-3321883 MSL acetylates histone H4 IEA Rattus norvegicus 57288 R-RNO-3371554 https://reactome.org/PathwayBrowser/#/R-RNO-3371554 HSF1 acetylation at Lys80 IEA Rattus norvegicus 57288 R-RNO-351207 https://reactome.org/PathwayBrowser/#/R-RNO-351207 Spermine => N-acetylated spermine IEA Rattus norvegicus 57288 R-RNO-351208 https://reactome.org/PathwayBrowser/#/R-RNO-351208 Spermidine => N-acetylated spermidine IEA Rattus norvegicus 57288 R-RNO-3662318 https://reactome.org/PathwayBrowser/#/R-RNO-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Rattus norvegicus 57288 R-RNO-390250 https://reactome.org/PathwayBrowser/#/R-RNO-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Rattus norvegicus 57288 R-RNO-390291 https://reactome.org/PathwayBrowser/#/R-RNO-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Rattus norvegicus 57288 R-RNO-390304 https://reactome.org/PathwayBrowser/#/R-RNO-390304 acetyl-CoA + H2O => acetate + CoASH IEA Rattus norvegicus 57288 R-RNO-449734 https://reactome.org/PathwayBrowser/#/R-RNO-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Rattus norvegicus 57288 R-RNO-449911 https://reactome.org/PathwayBrowser/#/R-RNO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Rattus norvegicus 57288 R-RNO-5250938 https://reactome.org/PathwayBrowser/#/R-RNO-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Rattus norvegicus 57288 R-RNO-5618328 https://reactome.org/PathwayBrowser/#/R-RNO-5618328 ATAT acetylates microtubules IEA Rattus norvegicus 57288 R-RNO-5628871 https://reactome.org/PathwayBrowser/#/R-RNO-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Rattus norvegicus 57288 R-RNO-5682044 https://reactome.org/PathwayBrowser/#/R-RNO-5682044 KAT5 acetylates ATM at DNA DSBs IEA Rattus norvegicus 57288 R-RNO-6788597 https://reactome.org/PathwayBrowser/#/R-RNO-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Rattus norvegicus 57288 R-RNO-6792712 https://reactome.org/PathwayBrowser/#/R-RNO-6792712 KAT5 acetylates ATM at shortened telomeres IEA Rattus norvegicus 57288 R-RNO-6805638 https://reactome.org/PathwayBrowser/#/R-RNO-6805638 KAT6A acetylates TP53 IEA Rattus norvegicus 57288 R-RNO-6811508 https://reactome.org/PathwayBrowser/#/R-RNO-6811508 ING2-bound EP300 acetylates TP53 IEA Rattus norvegicus 57288 R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 57288 R-RNO-70542 https://reactome.org/PathwayBrowser/#/R-RNO-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Rattus norvegicus 57288 R-RNO-70844 https://reactome.org/PathwayBrowser/#/R-RNO-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Rattus norvegicus 57288 R-RNO-70975 https://reactome.org/PathwayBrowser/#/R-RNO-70975 CS acetylates OA to citrate IEA Rattus norvegicus 57288 R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 57288 R-RNO-71735 https://reactome.org/PathwayBrowser/#/R-RNO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Rattus norvegicus 57288 R-RNO-727759 https://reactome.org/PathwayBrowser/#/R-RNO-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Rattus norvegicus 57288 R-RNO-73916 https://reactome.org/PathwayBrowser/#/R-RNO-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Rattus norvegicus 57288 R-RNO-73918 https://reactome.org/PathwayBrowser/#/R-RNO-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Rattus norvegicus 57288 R-RNO-74180 https://reactome.org/PathwayBrowser/#/R-RNO-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Rattus norvegicus 57288 R-RNO-74181 https://reactome.org/PathwayBrowser/#/R-RNO-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Rattus norvegicus 57288 R-RNO-75848 https://reactome.org/PathwayBrowser/#/R-RNO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Rattus norvegicus 57288 R-RNO-75851 https://reactome.org/PathwayBrowser/#/R-RNO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 57288 R-RNO-75872 https://reactome.org/PathwayBrowser/#/R-RNO-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Rattus norvegicus 57288 R-RNO-77271 https://reactome.org/PathwayBrowser/#/R-RNO-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Rattus norvegicus 57288 R-RNO-77304 https://reactome.org/PathwayBrowser/#/R-RNO-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Rattus norvegicus 57288 R-RNO-77309 https://reactome.org/PathwayBrowser/#/R-RNO-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Rattus norvegicus 57288 R-RNO-77321 https://reactome.org/PathwayBrowser/#/R-RNO-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Rattus norvegicus 57288 R-RNO-77329 https://reactome.org/PathwayBrowser/#/R-RNO-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Rattus norvegicus 57288 R-RNO-77340 https://reactome.org/PathwayBrowser/#/R-RNO-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Rattus norvegicus 57288 R-RNO-8848215 https://reactome.org/PathwayBrowser/#/R-RNO-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Rattus norvegicus 57288 R-RNO-8874745 https://reactome.org/PathwayBrowser/#/R-RNO-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Rattus norvegicus 57288 R-RNO-8875071 https://reactome.org/PathwayBrowser/#/R-RNO-8875071 ACSS3 ligates CoA to CH3COO- IEA Rattus norvegicus 57288 R-RNO-8876889 https://reactome.org/PathwayBrowser/#/R-RNO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 57288 R-RNO-8951966 https://reactome.org/PathwayBrowser/#/R-RNO-8951966 EP300 acetylates RUNX3 IEA Rattus norvegicus 57288 R-RNO-8954468 https://reactome.org/PathwayBrowser/#/R-RNO-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Rattus norvegicus 57288 R-RNO-9620515 https://reactome.org/PathwayBrowser/#/R-RNO-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Rattus norvegicus 57288 R-RNO-9701531 https://reactome.org/PathwayBrowser/#/R-RNO-9701531 p-Y705,S727 STAT3 is acetylated IEA Rattus norvegicus 57288 R-RNO-9753676 https://reactome.org/PathwayBrowser/#/R-RNO-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Rattus norvegicus 57288 R-RNO-9760081 https://reactome.org/PathwayBrowser/#/R-RNO-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Rattus norvegicus 57288 R-RNO-977317 https://reactome.org/PathwayBrowser/#/R-RNO-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Rattus norvegicus 57288 R-RNO-9825747 https://reactome.org/PathwayBrowser/#/R-RNO-9825747 CREBBP acetylates HINT1 dimer IEA Rattus norvegicus 57288 R-RNO-9854415 https://reactome.org/PathwayBrowser/#/R-RNO-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Rattus norvegicus 57288 R-RNO-9861667 https://reactome.org/PathwayBrowser/#/R-RNO-9861667 DLAT trimer transfers acetyl to CoA IEA Rattus norvegicus 57288 R-SCE-191323 https://reactome.org/PathwayBrowser/#/R-SCE-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Saccharomyces cerevisiae 57288 R-SCE-200555 https://reactome.org/PathwayBrowser/#/R-SCE-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Saccharomyces cerevisiae 57288 R-SCE-2066788 https://reactome.org/PathwayBrowser/#/R-SCE-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Saccharomyces cerevisiae 57288 R-SCE-209792 https://reactome.org/PathwayBrowser/#/R-SCE-209792 N-acetylation of serotonin IEA Saccharomyces cerevisiae 57288 R-SCE-2468039 https://reactome.org/PathwayBrowser/#/R-SCE-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Saccharomyces cerevisiae 57288 R-SCE-2473152 https://reactome.org/PathwayBrowser/#/R-SCE-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Saccharomyces cerevisiae 57288 R-SCE-2545253 https://reactome.org/PathwayBrowser/#/R-SCE-2545253 Deacetylation of cohesin IEA Saccharomyces cerevisiae 57288 R-SCE-3318415 https://reactome.org/PathwayBrowser/#/R-SCE-3318415 ATF2 acetylates histone H2B, H4 IEA Saccharomyces cerevisiae 57288 R-SCE-351207 https://reactome.org/PathwayBrowser/#/R-SCE-351207 Spermine => N-acetylated spermine IEA Saccharomyces cerevisiae 57288 R-SCE-351208 https://reactome.org/PathwayBrowser/#/R-SCE-351208 Spermidine => N-acetylated spermidine IEA Saccharomyces cerevisiae 57288 R-SCE-3662318 https://reactome.org/PathwayBrowser/#/R-SCE-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Saccharomyces cerevisiae 57288 R-SCE-390250 https://reactome.org/PathwayBrowser/#/R-SCE-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Saccharomyces cerevisiae 57288 R-SCE-390304 https://reactome.org/PathwayBrowser/#/R-SCE-390304 acetyl-CoA + H2O => acetate + CoASH IEA Saccharomyces cerevisiae 57288 R-SCE-449734 https://reactome.org/PathwayBrowser/#/R-SCE-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Saccharomyces cerevisiae 57288 R-SCE-449911 https://reactome.org/PathwayBrowser/#/R-SCE-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Saccharomyces cerevisiae 57288 R-SCE-5682044 https://reactome.org/PathwayBrowser/#/R-SCE-5682044 KAT5 acetylates ATM at DNA DSBs IEA Saccharomyces cerevisiae 57288 R-SCE-6792712 https://reactome.org/PathwayBrowser/#/R-SCE-6792712 KAT5 acetylates ATM at shortened telomeres IEA Saccharomyces cerevisiae 57288 R-SCE-6814089 https://reactome.org/PathwayBrowser/#/R-SCE-6814089 NatC acetylates ARL3 TAS Saccharomyces cerevisiae 57288 R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 57288 R-SCE-70542 https://reactome.org/PathwayBrowser/#/R-SCE-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Saccharomyces cerevisiae 57288 R-SCE-70975 https://reactome.org/PathwayBrowser/#/R-SCE-70975 CS acetylates OA to citrate IEA Saccharomyces cerevisiae 57288 R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 57288 R-SCE-71735 https://reactome.org/PathwayBrowser/#/R-SCE-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Saccharomyces cerevisiae 57288 R-SCE-727759 https://reactome.org/PathwayBrowser/#/R-SCE-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Saccharomyces cerevisiae 57288 R-SCE-73918 https://reactome.org/PathwayBrowser/#/R-SCE-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Saccharomyces cerevisiae 57288 R-SCE-75851 https://reactome.org/PathwayBrowser/#/R-SCE-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 57288 R-SCE-8848215 https://reactome.org/PathwayBrowser/#/R-SCE-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Saccharomyces cerevisiae 57288 R-SCE-8876889 https://reactome.org/PathwayBrowser/#/R-SCE-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 57288 R-SCE-9861667 https://reactome.org/PathwayBrowser/#/R-SCE-9861667 DLAT trimer transfers acetyl to CoA IEA Saccharomyces cerevisiae 57288 R-SPO-191323 https://reactome.org/PathwayBrowser/#/R-SPO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Schizosaccharomyces pombe 57288 R-SPO-200555 https://reactome.org/PathwayBrowser/#/R-SPO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Schizosaccharomyces pombe 57288 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 57288 R-SPO-209792 https://reactome.org/PathwayBrowser/#/R-SPO-209792 N-acetylation of serotonin IEA Schizosaccharomyces pombe 57288 R-SPO-3318413 https://reactome.org/PathwayBrowser/#/R-SPO-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Schizosaccharomyces pombe 57288 R-SPO-3318415 https://reactome.org/PathwayBrowser/#/R-SPO-3318415 ATF2 acetylates histone H2B, H4 IEA Schizosaccharomyces pombe 57288 R-SPO-3318486 https://reactome.org/PathwayBrowser/#/R-SPO-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Schizosaccharomyces pombe 57288 R-SPO-351207 https://reactome.org/PathwayBrowser/#/R-SPO-351207 Spermine => N-acetylated spermine IEA Schizosaccharomyces pombe 57288 R-SPO-351208 https://reactome.org/PathwayBrowser/#/R-SPO-351208 Spermidine => N-acetylated spermidine IEA Schizosaccharomyces pombe 57288 R-SPO-3662318 https://reactome.org/PathwayBrowser/#/R-SPO-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Schizosaccharomyces pombe 57288 R-SPO-449734 https://reactome.org/PathwayBrowser/#/R-SPO-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Schizosaccharomyces pombe 57288 R-SPO-449911 https://reactome.org/PathwayBrowser/#/R-SPO-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Schizosaccharomyces pombe 57288 R-SPO-5682044 https://reactome.org/PathwayBrowser/#/R-SPO-5682044 KAT5 acetylates ATM at DNA DSBs IEA Schizosaccharomyces pombe 57288 R-SPO-6792712 https://reactome.org/PathwayBrowser/#/R-SPO-6792712 KAT5 acetylates ATM at shortened telomeres IEA Schizosaccharomyces pombe 57288 R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 57288 R-SPO-70542 https://reactome.org/PathwayBrowser/#/R-SPO-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Schizosaccharomyces pombe 57288 R-SPO-70975 https://reactome.org/PathwayBrowser/#/R-SPO-70975 CS acetylates OA to citrate IEA Schizosaccharomyces pombe 57288 R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 57288 R-SPO-71735 https://reactome.org/PathwayBrowser/#/R-SPO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Schizosaccharomyces pombe 57288 R-SPO-727759 https://reactome.org/PathwayBrowser/#/R-SPO-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Schizosaccharomyces pombe 57288 R-SPO-73918 https://reactome.org/PathwayBrowser/#/R-SPO-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Schizosaccharomyces pombe 57288 R-SPO-75848 https://reactome.org/PathwayBrowser/#/R-SPO-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Schizosaccharomyces pombe 57288 R-SPO-75851 https://reactome.org/PathwayBrowser/#/R-SPO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 57288 R-SPO-8848215 https://reactome.org/PathwayBrowser/#/R-SPO-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Schizosaccharomyces pombe 57288 R-SPO-8876889 https://reactome.org/PathwayBrowser/#/R-SPO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 57288 R-SPO-9861667 https://reactome.org/PathwayBrowser/#/R-SPO-9861667 DLAT trimer transfers acetyl to CoA IEA Schizosaccharomyces pombe 57288 R-SSC-158832 https://reactome.org/PathwayBrowser/#/R-SSC-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 IEA Sus scrofa 57288 R-SSC-1678660 https://reactome.org/PathwayBrowser/#/R-SSC-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Sus scrofa 57288 R-SSC-174959 https://reactome.org/PathwayBrowser/#/R-SSC-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 IEA Sus scrofa 57288 R-SSC-191323 https://reactome.org/PathwayBrowser/#/R-SSC-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Sus scrofa 57288 R-SSC-200555 https://reactome.org/PathwayBrowser/#/R-SSC-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Sus scrofa 57288 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 57288 R-SSC-2066788 https://reactome.org/PathwayBrowser/#/R-SSC-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Sus scrofa 57288 R-SSC-2090085 https://reactome.org/PathwayBrowser/#/R-SSC-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Sus scrofa 57288 R-SSC-209792 https://reactome.org/PathwayBrowser/#/R-SSC-209792 N-acetylation of serotonin IEA Sus scrofa 57288 R-SSC-2468039 https://reactome.org/PathwayBrowser/#/R-SSC-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Sus scrofa 57288 R-SSC-2473152 https://reactome.org/PathwayBrowser/#/R-SSC-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Sus scrofa 57288 R-SSC-2545203 https://reactome.org/PathwayBrowser/#/R-SSC-2545203 Deacetylation of cleaved cohesin IEA Sus scrofa 57288 R-SSC-2545253 https://reactome.org/PathwayBrowser/#/R-SSC-2545253 Deacetylation of cohesin IEA Sus scrofa 57288 R-SSC-264622 https://reactome.org/PathwayBrowser/#/R-SSC-264622 Cho is acetylated to AcCho by CHAT IEA Sus scrofa 57288 R-SSC-3318413 https://reactome.org/PathwayBrowser/#/R-SSC-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Sus scrofa 57288 R-SSC-3318415 https://reactome.org/PathwayBrowser/#/R-SSC-3318415 ATF2 acetylates histone H2B, H4 IEA Sus scrofa 57288 R-SSC-3318486 https://reactome.org/PathwayBrowser/#/R-SSC-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Sus scrofa 57288 R-SSC-3321805 https://reactome.org/PathwayBrowser/#/R-SSC-3321805 NSL acetylates histone H4 IEA Sus scrofa 57288 R-SSC-3321883 https://reactome.org/PathwayBrowser/#/R-SSC-3321883 MSL acetylates histone H4 IEA Sus scrofa 57288 R-SSC-3371554 https://reactome.org/PathwayBrowser/#/R-SSC-3371554 HSF1 acetylation at Lys80 IEA Sus scrofa 57288 R-SSC-351207 https://reactome.org/PathwayBrowser/#/R-SSC-351207 Spermine => N-acetylated spermine IEA Sus scrofa 57288 R-SSC-351208 https://reactome.org/PathwayBrowser/#/R-SSC-351208 Spermidine => N-acetylated spermidine IEA Sus scrofa 57288 R-SSC-3662318 https://reactome.org/PathwayBrowser/#/R-SSC-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Sus scrofa 57288 R-SSC-3662335 https://reactome.org/PathwayBrowser/#/R-SSC-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Sus scrofa 57288 R-SSC-390250 https://reactome.org/PathwayBrowser/#/R-SSC-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Sus scrofa 57288 R-SSC-390291 https://reactome.org/PathwayBrowser/#/R-SSC-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Sus scrofa 57288 R-SSC-390304 https://reactome.org/PathwayBrowser/#/R-SSC-390304 acetyl-CoA + H2O => acetate + CoASH IEA Sus scrofa 57288 R-SSC-449734 https://reactome.org/PathwayBrowser/#/R-SSC-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Sus scrofa 57288 R-SSC-449911 https://reactome.org/PathwayBrowser/#/R-SSC-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Sus scrofa 57288 R-SSC-5250938 https://reactome.org/PathwayBrowser/#/R-SSC-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Sus scrofa 57288 R-SSC-5618328 https://reactome.org/PathwayBrowser/#/R-SSC-5618328 ATAT acetylates microtubules IEA Sus scrofa 57288 R-SSC-5618331 https://reactome.org/PathwayBrowser/#/R-SSC-5618331 HDAC6 deacetylates microtubules IEA Sus scrofa 57288 R-SSC-5628871 https://reactome.org/PathwayBrowser/#/R-SSC-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Sus scrofa 57288 R-SSC-5660660 https://reactome.org/PathwayBrowser/#/R-SSC-5660660 p300 acetylates RELA subunit IEA Sus scrofa 57288 R-SSC-5682044 https://reactome.org/PathwayBrowser/#/R-SSC-5682044 KAT5 acetylates ATM at DNA DSBs IEA Sus scrofa 57288 R-SSC-6788597 https://reactome.org/PathwayBrowser/#/R-SSC-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Sus scrofa 57288 R-SSC-6792712 https://reactome.org/PathwayBrowser/#/R-SSC-6792712 KAT5 acetylates ATM at shortened telomeres IEA Sus scrofa 57288 R-SSC-6805638 https://reactome.org/PathwayBrowser/#/R-SSC-6805638 KAT6A acetylates TP53 IEA Sus scrofa 57288 R-SSC-6811508 https://reactome.org/PathwayBrowser/#/R-SSC-6811508 ING2-bound EP300 acetylates TP53 IEA Sus scrofa 57288 R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 57288 R-SSC-70542 https://reactome.org/PathwayBrowser/#/R-SSC-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Sus scrofa 57288 R-SSC-70844 https://reactome.org/PathwayBrowser/#/R-SSC-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Sus scrofa 57288 R-SSC-70975 https://reactome.org/PathwayBrowser/#/R-SSC-70975 CS acetylates OA to citrate IEA Sus scrofa 57288 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 57288 R-SSC-71735 https://reactome.org/PathwayBrowser/#/R-SSC-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Sus scrofa 57288 R-SSC-727759 https://reactome.org/PathwayBrowser/#/R-SSC-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Sus scrofa 57288 R-SSC-73916 https://reactome.org/PathwayBrowser/#/R-SSC-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Sus scrofa 57288 R-SSC-73918 https://reactome.org/PathwayBrowser/#/R-SSC-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Sus scrofa 57288 R-SSC-74180 https://reactome.org/PathwayBrowser/#/R-SSC-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Sus scrofa 57288 R-SSC-74181 https://reactome.org/PathwayBrowser/#/R-SSC-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Sus scrofa 57288 R-SSC-75848 https://reactome.org/PathwayBrowser/#/R-SSC-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Sus scrofa 57288 R-SSC-75851 https://reactome.org/PathwayBrowser/#/R-SSC-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 57288 R-SSC-75872 https://reactome.org/PathwayBrowser/#/R-SSC-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Sus scrofa 57288 R-SSC-77271 https://reactome.org/PathwayBrowser/#/R-SSC-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Sus scrofa 57288 R-SSC-77304 https://reactome.org/PathwayBrowser/#/R-SSC-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Sus scrofa 57288 R-SSC-77309 https://reactome.org/PathwayBrowser/#/R-SSC-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Sus scrofa 57288 R-SSC-77321 https://reactome.org/PathwayBrowser/#/R-SSC-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Sus scrofa 57288 R-SSC-77329 https://reactome.org/PathwayBrowser/#/R-SSC-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Sus scrofa 57288 R-SSC-77340 https://reactome.org/PathwayBrowser/#/R-SSC-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Sus scrofa 57288 R-SSC-8848215 https://reactome.org/PathwayBrowser/#/R-SSC-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Sus scrofa 57288 R-SSC-8874745 https://reactome.org/PathwayBrowser/#/R-SSC-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Sus scrofa 57288 R-SSC-8875071 https://reactome.org/PathwayBrowser/#/R-SSC-8875071 ACSS3 ligates CoA to CH3COO- IEA Sus scrofa 57288 R-SSC-8876889 https://reactome.org/PathwayBrowser/#/R-SSC-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 57288 R-SSC-8951966 https://reactome.org/PathwayBrowser/#/R-SSC-8951966 EP300 acetylates RUNX3 IEA Sus scrofa 57288 R-SSC-8954468 https://reactome.org/PathwayBrowser/#/R-SSC-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Sus scrofa 57288 R-SSC-9620515 https://reactome.org/PathwayBrowser/#/R-SSC-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Sus scrofa 57288 R-SSC-9701531 https://reactome.org/PathwayBrowser/#/R-SSC-9701531 p-Y705,S727 STAT3 is acetylated IEA Sus scrofa 57288 R-SSC-9753676 https://reactome.org/PathwayBrowser/#/R-SSC-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Sus scrofa 57288 R-SSC-9760081 https://reactome.org/PathwayBrowser/#/R-SSC-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Sus scrofa 57288 R-SSC-977317 https://reactome.org/PathwayBrowser/#/R-SSC-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Sus scrofa 57288 R-SSC-9825747 https://reactome.org/PathwayBrowser/#/R-SSC-9825747 CREBBP acetylates HINT1 dimer IEA Sus scrofa 57288 R-SSC-9854415 https://reactome.org/PathwayBrowser/#/R-SSC-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Sus scrofa 57288 R-SSC-9861667 https://reactome.org/PathwayBrowser/#/R-SSC-9861667 DLAT trimer transfers acetyl to CoA IEA Sus scrofa 57288 R-XTR-1678660 https://reactome.org/PathwayBrowser/#/R-XTR-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Xenopus tropicalis 57288 R-XTR-200555 https://reactome.org/PathwayBrowser/#/R-XTR-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Xenopus tropicalis 57288 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 57288 R-XTR-2066788 https://reactome.org/PathwayBrowser/#/R-XTR-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Xenopus tropicalis 57288 R-XTR-2090085 https://reactome.org/PathwayBrowser/#/R-XTR-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Xenopus tropicalis 57288 R-XTR-3318415 https://reactome.org/PathwayBrowser/#/R-XTR-3318415 ATF2 acetylates histone H2B, H4 IEA Xenopus tropicalis 57288 R-XTR-351207 https://reactome.org/PathwayBrowser/#/R-XTR-351207 Spermine => N-acetylated spermine IEA Xenopus tropicalis 57288 R-XTR-351208 https://reactome.org/PathwayBrowser/#/R-XTR-351208 Spermidine => N-acetylated spermidine IEA Xenopus tropicalis 57288 R-XTR-3662335 https://reactome.org/PathwayBrowser/#/R-XTR-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Xenopus tropicalis 57288 R-XTR-390250 https://reactome.org/PathwayBrowser/#/R-XTR-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Xenopus tropicalis 57288 R-XTR-390291 https://reactome.org/PathwayBrowser/#/R-XTR-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Xenopus tropicalis 57288 R-XTR-390304 https://reactome.org/PathwayBrowser/#/R-XTR-390304 acetyl-CoA + H2O => acetate + CoASH IEA Xenopus tropicalis 57288 R-XTR-449734 https://reactome.org/PathwayBrowser/#/R-XTR-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Xenopus tropicalis 57288 R-XTR-449911 https://reactome.org/PathwayBrowser/#/R-XTR-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Xenopus tropicalis 57288 R-XTR-5618328 https://reactome.org/PathwayBrowser/#/R-XTR-5618328 ATAT acetylates microtubules IEA Xenopus tropicalis 57288 R-XTR-5628871 https://reactome.org/PathwayBrowser/#/R-XTR-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Xenopus tropicalis 57288 R-XTR-6788597 https://reactome.org/PathwayBrowser/#/R-XTR-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Xenopus tropicalis 57288 R-XTR-6805638 https://reactome.org/PathwayBrowser/#/R-XTR-6805638 KAT6A acetylates TP53 IEA Xenopus tropicalis 57288 R-XTR-6811508 https://reactome.org/PathwayBrowser/#/R-XTR-6811508 ING2-bound EP300 acetylates TP53 IEA Xenopus tropicalis 57288 R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 57288 R-XTR-70542 https://reactome.org/PathwayBrowser/#/R-XTR-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA IEA Xenopus tropicalis 57288 R-XTR-70844 https://reactome.org/PathwayBrowser/#/R-XTR-70844 alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA IEA Xenopus tropicalis 57288 R-XTR-70975 https://reactome.org/PathwayBrowser/#/R-XTR-70975 CS acetylates OA to citrate IEA Xenopus tropicalis 57288 R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 57288 R-XTR-71735 https://reactome.org/PathwayBrowser/#/R-XTR-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Xenopus tropicalis 57288 R-XTR-727759 https://reactome.org/PathwayBrowser/#/R-XTR-727759 SLC33A1 transports Ac-CoA from cytosol to Golgi lumen IEA Xenopus tropicalis 57288 R-XTR-73916 https://reactome.org/PathwayBrowser/#/R-XTR-73916 2 acetyl-CoA <=> acetoacetyl-CoA + CoA IEA Xenopus tropicalis 57288 R-XTR-74180 https://reactome.org/PathwayBrowser/#/R-XTR-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Xenopus tropicalis 57288 R-XTR-74181 https://reactome.org/PathwayBrowser/#/R-XTR-74181 acetoacetyl-CoA + CoA <=> 2 acetyl-CoA IEA Xenopus tropicalis 57288 R-XTR-75848 https://reactome.org/PathwayBrowser/#/R-XTR-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Xenopus tropicalis 57288 R-XTR-75851 https://reactome.org/PathwayBrowser/#/R-XTR-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 57288 R-XTR-75872 https://reactome.org/PathwayBrowser/#/R-XTR-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Xenopus tropicalis 57288 R-XTR-77271 https://reactome.org/PathwayBrowser/#/R-XTR-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Xenopus tropicalis 57288 R-XTR-77304 https://reactome.org/PathwayBrowser/#/R-XTR-77304 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA IEA Xenopus tropicalis 57288 R-XTR-77309 https://reactome.org/PathwayBrowser/#/R-XTR-77309 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA IEA Xenopus tropicalis 57288 R-XTR-77321 https://reactome.org/PathwayBrowser/#/R-XTR-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Xenopus tropicalis 57288 R-XTR-77329 https://reactome.org/PathwayBrowser/#/R-XTR-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Xenopus tropicalis 57288 R-XTR-77340 https://reactome.org/PathwayBrowser/#/R-XTR-77340 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA IEA Xenopus tropicalis 57288 R-XTR-8848215 https://reactome.org/PathwayBrowser/#/R-XTR-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Xenopus tropicalis 57288 R-XTR-8874745 https://reactome.org/PathwayBrowser/#/R-XTR-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Xenopus tropicalis 57288 R-XTR-8875071 https://reactome.org/PathwayBrowser/#/R-XTR-8875071 ACSS3 ligates CoA to CH3COO- IEA Xenopus tropicalis 57288 R-XTR-8876889 https://reactome.org/PathwayBrowser/#/R-XTR-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 57288 R-XTR-8954468 https://reactome.org/PathwayBrowser/#/R-XTR-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA IEA Xenopus tropicalis 57288 R-XTR-9620515 https://reactome.org/PathwayBrowser/#/R-XTR-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Xenopus tropicalis 57288 R-XTR-9701531 https://reactome.org/PathwayBrowser/#/R-XTR-9701531 p-Y705,S727 STAT3 is acetylated IEA Xenopus tropicalis 57288 R-XTR-9760081 https://reactome.org/PathwayBrowser/#/R-XTR-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Xenopus tropicalis 57288 R-XTR-977317 https://reactome.org/PathwayBrowser/#/R-XTR-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Xenopus tropicalis 57288 R-XTR-9854415 https://reactome.org/PathwayBrowser/#/R-XTR-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Xenopus tropicalis 57288 R-XTR-9861667 https://reactome.org/PathwayBrowser/#/R-XTR-9861667 DLAT trimer transfers acetyl to CoA IEA Xenopus tropicalis 57292 R-BTA-189442 https://reactome.org/PathwayBrowser/#/R-BTA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Bos taurus 57292 R-BTA-70997 https://reactome.org/PathwayBrowser/#/R-BTA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Bos taurus 57292 R-BTA-71010 https://reactome.org/PathwayBrowser/#/R-BTA-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Bos taurus 57292 R-BTA-71775 https://reactome.org/PathwayBrowser/#/R-BTA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Bos taurus 57292 R-BTA-74177 https://reactome.org/PathwayBrowser/#/R-BTA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Bos taurus 57292 R-BTA-9853512 https://reactome.org/PathwayBrowser/#/R-BTA-9853512 DLST transfers succinyl to CoA IEA Bos taurus 57292 R-CEL-70997 https://reactome.org/PathwayBrowser/#/R-CEL-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Caenorhabditis elegans 57292 R-CEL-71010 https://reactome.org/PathwayBrowser/#/R-CEL-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Caenorhabditis elegans 57292 R-CEL-71775 https://reactome.org/PathwayBrowser/#/R-CEL-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Caenorhabditis elegans 57292 R-CEL-74177 https://reactome.org/PathwayBrowser/#/R-CEL-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Caenorhabditis elegans 57292 R-CEL-9853512 https://reactome.org/PathwayBrowser/#/R-CEL-9853512 DLST transfers succinyl to CoA IEA Caenorhabditis elegans 57292 R-CFA-189442 https://reactome.org/PathwayBrowser/#/R-CFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Canis familiaris 57292 R-CFA-70997 https://reactome.org/PathwayBrowser/#/R-CFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Canis familiaris 57292 R-CFA-71010 https://reactome.org/PathwayBrowser/#/R-CFA-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Canis familiaris 57292 R-CFA-71775 https://reactome.org/PathwayBrowser/#/R-CFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Canis familiaris 57292 R-CFA-74177 https://reactome.org/PathwayBrowser/#/R-CFA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Canis familiaris 57292 R-CFA-9853512 https://reactome.org/PathwayBrowser/#/R-CFA-9853512 DLST transfers succinyl to CoA IEA Canis familiaris 57292 R-DDI-189442 https://reactome.org/PathwayBrowser/#/R-DDI-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Dictyostelium discoideum 57292 R-DDI-70997 https://reactome.org/PathwayBrowser/#/R-DDI-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Dictyostelium discoideum 57292 R-DDI-71775 https://reactome.org/PathwayBrowser/#/R-DDI-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Dictyostelium discoideum 57292 R-DDI-74177 https://reactome.org/PathwayBrowser/#/R-DDI-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Dictyostelium discoideum 57292 R-DDI-9853512 https://reactome.org/PathwayBrowser/#/R-DDI-9853512 DLST transfers succinyl to CoA IEA Dictyostelium discoideum 57292 R-DME-189442 https://reactome.org/PathwayBrowser/#/R-DME-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Drosophila melanogaster 57292 R-DME-70997 https://reactome.org/PathwayBrowser/#/R-DME-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Drosophila melanogaster 57292 R-DME-71775 https://reactome.org/PathwayBrowser/#/R-DME-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Drosophila melanogaster 57292 R-DME-74177 https://reactome.org/PathwayBrowser/#/R-DME-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Drosophila melanogaster 57292 R-DME-9853512 https://reactome.org/PathwayBrowser/#/R-DME-9853512 DLST transfers succinyl to CoA IEA Drosophila melanogaster 57292 R-DRE-189442 https://reactome.org/PathwayBrowser/#/R-DRE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Danio rerio 57292 R-DRE-70997 https://reactome.org/PathwayBrowser/#/R-DRE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Danio rerio 57292 R-DRE-71010 https://reactome.org/PathwayBrowser/#/R-DRE-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Danio rerio 57292 R-DRE-74177 https://reactome.org/PathwayBrowser/#/R-DRE-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Danio rerio 57292 R-DRE-9853512 https://reactome.org/PathwayBrowser/#/R-DRE-9853512 DLST transfers succinyl to CoA IEA Danio rerio 57292 R-GGA-189442 https://reactome.org/PathwayBrowser/#/R-GGA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Gallus gallus 57292 R-GGA-372977 https://reactome.org/PathwayBrowser/#/R-GGA-372977 succinylCoA + ADP + Pi <=> succinate + CoASH + ATP TAS Gallus gallus 57292 R-GGA-372980 https://reactome.org/PathwayBrowser/#/R-GGA-372980 succinylCoA + GDP + Pi <=> succinate + CoASH + GTP TAS Gallus gallus 57292 R-GGA-373042 https://reactome.org/PathwayBrowser/#/R-GGA-373042 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ IEA Gallus gallus 57292 R-GGA-373134 https://reactome.org/PathwayBrowser/#/R-GGA-373134 succinate + CoASH + ATP <=> succinylCoA + ADP + Pi TAS Gallus gallus 57292 R-GGA-373148 https://reactome.org/PathwayBrowser/#/R-GGA-373148 succinate + CoASH + GTP <=> succinylCoA + GDP + Pi TAS Gallus gallus 57292 R-GGA-421493 https://reactome.org/PathwayBrowser/#/R-GGA-421493 succinyl-CoA + glycine => delta-aminolevulinate + CoA SH + CO2 TAS Gallus gallus 57292 R-GGA-70997 https://reactome.org/PathwayBrowser/#/R-GGA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Gallus gallus 57292 R-GGA-71010 https://reactome.org/PathwayBrowser/#/R-GGA-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Gallus gallus 57292 R-GGA-71775 https://reactome.org/PathwayBrowser/#/R-GGA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Gallus gallus 57292 R-GGA-74177 https://reactome.org/PathwayBrowser/#/R-GGA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Gallus gallus 57292 R-GGA-9853512 https://reactome.org/PathwayBrowser/#/R-GGA-9853512 DLST transfers succinyl to CoA IEA Gallus gallus 57292 R-HSA-189442 https://reactome.org/PathwayBrowser/#/R-HSA-189442 ALAS condenses SUCC-CoA and Gly to form dALA TAS Homo sapiens 57292 R-HSA-70997 https://reactome.org/PathwayBrowser/#/R-HSA-70997 SUCLG1/A2 cleaves succinyl-CoA TAS Homo sapiens 57292 R-HSA-71010 https://reactome.org/PathwayBrowser/#/R-HSA-71010 MUT isomerises L-MM-CoA to SUCC-CoA TAS Homo sapiens 57292 R-HSA-71775 https://reactome.org/PathwayBrowser/#/R-HSA-71775 SUCLG1/G2 cleaves succinyl-CoA TAS Homo sapiens 57292 R-HSA-74177 https://reactome.org/PathwayBrowser/#/R-HSA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA TAS Homo sapiens 57292 R-HSA-9853512 https://reactome.org/PathwayBrowser/#/R-HSA-9853512 DLST transfers succinyl to CoA TAS Homo sapiens 57292 R-MMU-189442 https://reactome.org/PathwayBrowser/#/R-MMU-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Mus musculus 57292 R-MMU-70997 https://reactome.org/PathwayBrowser/#/R-MMU-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Mus musculus 57292 R-MMU-71010 https://reactome.org/PathwayBrowser/#/R-MMU-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Mus musculus 57292 R-MMU-71775 https://reactome.org/PathwayBrowser/#/R-MMU-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Mus musculus 57292 R-MMU-74177 https://reactome.org/PathwayBrowser/#/R-MMU-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Mus musculus 57292 R-MMU-9853512 https://reactome.org/PathwayBrowser/#/R-MMU-9853512 DLST transfers succinyl to CoA IEA Mus musculus 57292 R-PFA-189442 https://reactome.org/PathwayBrowser/#/R-PFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Plasmodium falciparum 57292 R-PFA-70997 https://reactome.org/PathwayBrowser/#/R-PFA-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Plasmodium falciparum 57292 R-PFA-71775 https://reactome.org/PathwayBrowser/#/R-PFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Plasmodium falciparum 57292 R-PFA-9853512 https://reactome.org/PathwayBrowser/#/R-PFA-9853512 DLST transfers succinyl to CoA IEA Plasmodium falciparum 57292 R-RNO-189442 https://reactome.org/PathwayBrowser/#/R-RNO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Rattus norvegicus 57292 R-RNO-70997 https://reactome.org/PathwayBrowser/#/R-RNO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Rattus norvegicus 57292 R-RNO-71010 https://reactome.org/PathwayBrowser/#/R-RNO-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Rattus norvegicus 57292 R-RNO-71775 https://reactome.org/PathwayBrowser/#/R-RNO-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Rattus norvegicus 57292 R-RNO-74177 https://reactome.org/PathwayBrowser/#/R-RNO-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Rattus norvegicus 57292 R-RNO-9853512 https://reactome.org/PathwayBrowser/#/R-RNO-9853512 DLST transfers succinyl to CoA IEA Rattus norvegicus 57292 R-SCE-189442 https://reactome.org/PathwayBrowser/#/R-SCE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Saccharomyces cerevisiae 57292 R-SCE-70997 https://reactome.org/PathwayBrowser/#/R-SCE-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Saccharomyces cerevisiae 57292 R-SCE-9853512 https://reactome.org/PathwayBrowser/#/R-SCE-9853512 DLST transfers succinyl to CoA IEA Saccharomyces cerevisiae 57292 R-SPO-189442 https://reactome.org/PathwayBrowser/#/R-SPO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Schizosaccharomyces pombe 57292 R-SPO-70997 https://reactome.org/PathwayBrowser/#/R-SPO-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Schizosaccharomyces pombe 57292 R-SPO-9853512 https://reactome.org/PathwayBrowser/#/R-SPO-9853512 DLST transfers succinyl to CoA IEA Schizosaccharomyces pombe 57292 R-SSC-189442 https://reactome.org/PathwayBrowser/#/R-SSC-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Sus scrofa 57292 R-SSC-70997 https://reactome.org/PathwayBrowser/#/R-SSC-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Sus scrofa 57292 R-SSC-71010 https://reactome.org/PathwayBrowser/#/R-SSC-71010 MUT isomerises L-MM-CoA to SUCC-CoA IEA Sus scrofa 57292 R-SSC-71775 https://reactome.org/PathwayBrowser/#/R-SSC-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Sus scrofa 57292 R-SSC-74177 https://reactome.org/PathwayBrowser/#/R-SSC-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Sus scrofa 57292 R-SSC-9853512 https://reactome.org/PathwayBrowser/#/R-SSC-9853512 DLST transfers succinyl to CoA IEA Sus scrofa 57292 R-XTR-189442 https://reactome.org/PathwayBrowser/#/R-XTR-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Xenopus tropicalis 57292 R-XTR-70997 https://reactome.org/PathwayBrowser/#/R-XTR-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Xenopus tropicalis 57292 R-XTR-71775 https://reactome.org/PathwayBrowser/#/R-XTR-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Xenopus tropicalis 57292 R-XTR-74177 https://reactome.org/PathwayBrowser/#/R-XTR-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Xenopus tropicalis 57292 R-XTR-9853512 https://reactome.org/PathwayBrowser/#/R-XTR-9853512 DLST transfers succinyl to CoA IEA Xenopus tropicalis 57305 R-BTA-1247910 https://reactome.org/PathwayBrowser/#/R-BTA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Bos taurus 57305 R-BTA-159566 https://reactome.org/PathwayBrowser/#/R-BTA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Bos taurus 57305 R-BTA-159574 https://reactome.org/PathwayBrowser/#/R-BTA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Bos taurus 57305 R-BTA-174394 https://reactome.org/PathwayBrowser/#/R-BTA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Bos taurus 57305 R-BTA-189442 https://reactome.org/PathwayBrowser/#/R-BTA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Bos taurus 57305 R-BTA-200651 https://reactome.org/PathwayBrowser/#/R-BTA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Bos taurus 57305 R-BTA-200735 https://reactome.org/PathwayBrowser/#/R-BTA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Bos taurus 57305 R-BTA-266012 https://reactome.org/PathwayBrowser/#/R-BTA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Bos taurus 57305 R-BTA-351963 https://reactome.org/PathwayBrowser/#/R-BTA-351963 SLC6A18 transports Gly from extracellular region to cytosol IEA Bos taurus 57305 R-BTA-352108 https://reactome.org/PathwayBrowser/#/R-BTA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Bos taurus 57305 R-BTA-352182 https://reactome.org/PathwayBrowser/#/R-BTA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Bos taurus 57305 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 57305 R-BTA-375405 https://reactome.org/PathwayBrowser/#/R-BTA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Bos taurus 57305 R-BTA-375417 https://reactome.org/PathwayBrowser/#/R-BTA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Bos taurus 57305 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 57305 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 57305 R-BTA-376200 https://reactome.org/PathwayBrowser/#/R-BTA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Bos taurus 57305 R-BTA-389684 https://reactome.org/PathwayBrowser/#/R-BTA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Bos taurus 57305 R-BTA-389821 https://reactome.org/PathwayBrowser/#/R-BTA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Bos taurus 57305 R-BTA-428625 https://reactome.org/PathwayBrowser/#/R-BTA-428625 Vesicular inhibitory amino acid transport IEA Bos taurus 57305 R-BTA-432164 https://reactome.org/PathwayBrowser/#/R-BTA-432164 Ca2+ influx into the post-synaptic cell IEA Bos taurus 57305 R-BTA-438037 https://reactome.org/PathwayBrowser/#/R-BTA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Bos taurus 57305 R-BTA-444120 https://reactome.org/PathwayBrowser/#/R-BTA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 57305 R-BTA-5433067 https://reactome.org/PathwayBrowser/#/R-BTA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Bos taurus 57305 R-BTA-5672965 https://reactome.org/PathwayBrowser/#/R-BTA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Bos taurus 57305 R-BTA-5693967 https://reactome.org/PathwayBrowser/#/R-BTA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Bos taurus 57305 R-BTA-5694137 https://reactome.org/PathwayBrowser/#/R-BTA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Bos taurus 57305 R-BTA-6797913 https://reactome.org/PathwayBrowser/#/R-BTA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Bos taurus 57305 R-BTA-6798317 https://reactome.org/PathwayBrowser/#/R-BTA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Bos taurus 57305 R-BTA-71249 https://reactome.org/PathwayBrowser/#/R-BTA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Bos taurus 57305 R-BTA-71275 https://reactome.org/PathwayBrowser/#/R-BTA-71275 arginine + glycine => ornithine + guanidoacetate IEA Bos taurus 57305 R-BTA-73814 https://reactome.org/PathwayBrowser/#/R-BTA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Bos taurus 57305 R-BTA-8867370 https://reactome.org/PathwayBrowser/#/R-BTA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Bos taurus 57305 R-BTA-904864 https://reactome.org/PathwayBrowser/#/R-BTA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Bos taurus 57305 R-BTA-9750001 https://reactome.org/PathwayBrowser/#/R-BTA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Bos taurus 57305 R-BTA-9753632 https://reactome.org/PathwayBrowser/#/R-BTA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Bos taurus 57305 R-BTA-975389 https://reactome.org/PathwayBrowser/#/R-BTA-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Bos taurus 57305 R-CEL-1247910 https://reactome.org/PathwayBrowser/#/R-CEL-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Caenorhabditis elegans 57305 R-CEL-159431 https://reactome.org/PathwayBrowser/#/R-CEL-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Caenorhabditis elegans 57305 R-CEL-159566 https://reactome.org/PathwayBrowser/#/R-CEL-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Caenorhabditis elegans 57305 R-CEL-159574 https://reactome.org/PathwayBrowser/#/R-CEL-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Caenorhabditis elegans 57305 R-CEL-174394 https://reactome.org/PathwayBrowser/#/R-CEL-174394 GSS:Mg2+ dimer synthesizes GSH IEA Caenorhabditis elegans 57305 R-CEL-192312 https://reactome.org/PathwayBrowser/#/R-CEL-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Caenorhabditis elegans 57305 R-CEL-193491 https://reactome.org/PathwayBrowser/#/R-CEL-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Caenorhabditis elegans 57305 R-CEL-200651 https://reactome.org/PathwayBrowser/#/R-CEL-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Caenorhabditis elegans 57305 R-CEL-200735 https://reactome.org/PathwayBrowser/#/R-CEL-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Caenorhabditis elegans 57305 R-CEL-375405 https://reactome.org/PathwayBrowser/#/R-CEL-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Caenorhabditis elegans 57305 R-CEL-375417 https://reactome.org/PathwayBrowser/#/R-CEL-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Caenorhabditis elegans 57305 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 57305 R-CEL-389684 https://reactome.org/PathwayBrowser/#/R-CEL-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Caenorhabditis elegans 57305 R-CEL-389821 https://reactome.org/PathwayBrowser/#/R-CEL-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Caenorhabditis elegans 57305 R-CEL-3928627 https://reactome.org/PathwayBrowser/#/R-CEL-3928627 EPHB phosphorylates TIAM1 IEA Caenorhabditis elegans 57305 R-CEL-3928645 https://reactome.org/PathwayBrowser/#/R-CEL-3928645 EPHB:NMDAR binds TIAM1 IEA Caenorhabditis elegans 57305 R-CEL-4093336 https://reactome.org/PathwayBrowser/#/R-CEL-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 57305 R-CEL-428625 https://reactome.org/PathwayBrowser/#/R-CEL-428625 Vesicular inhibitory amino acid transport IEA Caenorhabditis elegans 57305 R-CEL-432164 https://reactome.org/PathwayBrowser/#/R-CEL-432164 Ca2+ influx into the post-synaptic cell IEA Caenorhabditis elegans 57305 R-CEL-438037 https://reactome.org/PathwayBrowser/#/R-CEL-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Caenorhabditis elegans 57305 R-CEL-444120 https://reactome.org/PathwayBrowser/#/R-CEL-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 57305 R-CEL-5693967 https://reactome.org/PathwayBrowser/#/R-CEL-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Caenorhabditis elegans 57305 R-CEL-71249 https://reactome.org/PathwayBrowser/#/R-CEL-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Caenorhabditis elegans 57305 R-CEL-73814 https://reactome.org/PathwayBrowser/#/R-CEL-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Caenorhabditis elegans 57305 R-CEL-8849878 https://reactome.org/PathwayBrowser/#/R-CEL-8849878 PSD-95 binds NMDA receptor IEA Caenorhabditis elegans 57305 R-CEL-8849881 https://reactome.org/PathwayBrowser/#/R-CEL-8849881 SALM2 associate with AMPA and NMDA receptors IEA Caenorhabditis elegans 57305 R-CEL-8849906 https://reactome.org/PathwayBrowser/#/R-CEL-8849906 SALM1 binds NMDA receptor IEA Caenorhabditis elegans 57305 R-CEL-904864 https://reactome.org/PathwayBrowser/#/R-CEL-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Caenorhabditis elegans 57305 R-CEL-9750001 https://reactome.org/PathwayBrowser/#/R-CEL-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Caenorhabditis elegans 57305 R-CEL-9753632 https://reactome.org/PathwayBrowser/#/R-CEL-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Caenorhabditis elegans 57305 R-CEL-975389 https://reactome.org/PathwayBrowser/#/R-CEL-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Caenorhabditis elegans 57305 R-CFA-1247910 https://reactome.org/PathwayBrowser/#/R-CFA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Canis familiaris 57305 R-CFA-159431 https://reactome.org/PathwayBrowser/#/R-CFA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Canis familiaris 57305 R-CFA-159566 https://reactome.org/PathwayBrowser/#/R-CFA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Canis familiaris 57305 R-CFA-159574 https://reactome.org/PathwayBrowser/#/R-CFA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Canis familiaris 57305 R-CFA-174394 https://reactome.org/PathwayBrowser/#/R-CFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Canis familiaris 57305 R-CFA-189442 https://reactome.org/PathwayBrowser/#/R-CFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Canis familiaris 57305 R-CFA-192312 https://reactome.org/PathwayBrowser/#/R-CFA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Canis familiaris 57305 R-CFA-193491 https://reactome.org/PathwayBrowser/#/R-CFA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Canis familiaris 57305 R-CFA-200651 https://reactome.org/PathwayBrowser/#/R-CFA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Canis familiaris 57305 R-CFA-200735 https://reactome.org/PathwayBrowser/#/R-CFA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Canis familiaris 57305 R-CFA-266012 https://reactome.org/PathwayBrowser/#/R-CFA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Canis familiaris 57305 R-CFA-351963 https://reactome.org/PathwayBrowser/#/R-CFA-351963 SLC6A18 transports Gly from extracellular region to cytosol IEA Canis familiaris 57305 R-CFA-352108 https://reactome.org/PathwayBrowser/#/R-CFA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Canis familiaris 57305 R-CFA-352182 https://reactome.org/PathwayBrowser/#/R-CFA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Canis familiaris 57305 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 57305 R-CFA-375405 https://reactome.org/PathwayBrowser/#/R-CFA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Canis familiaris 57305 R-CFA-375417 https://reactome.org/PathwayBrowser/#/R-CFA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Canis familiaris 57305 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 57305 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 57305 R-CFA-376200 https://reactome.org/PathwayBrowser/#/R-CFA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Canis familiaris 57305 R-CFA-389684 https://reactome.org/PathwayBrowser/#/R-CFA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Canis familiaris 57305 R-CFA-389821 https://reactome.org/PathwayBrowser/#/R-CFA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Canis familiaris 57305 R-CFA-3928627 https://reactome.org/PathwayBrowser/#/R-CFA-3928627 EPHB phosphorylates TIAM1 IEA Canis familiaris 57305 R-CFA-3928645 https://reactome.org/PathwayBrowser/#/R-CFA-3928645 EPHB:NMDAR binds TIAM1 IEA Canis familiaris 57305 R-CFA-4093336 https://reactome.org/PathwayBrowser/#/R-CFA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 57305 R-CFA-428625 https://reactome.org/PathwayBrowser/#/R-CFA-428625 Vesicular inhibitory amino acid transport IEA Canis familiaris 57305 R-CFA-432164 https://reactome.org/PathwayBrowser/#/R-CFA-432164 Ca2+ influx into the post-synaptic cell IEA Canis familiaris 57305 R-CFA-438037 https://reactome.org/PathwayBrowser/#/R-CFA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Canis familiaris 57305 R-CFA-444120 https://reactome.org/PathwayBrowser/#/R-CFA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 57305 R-CFA-5433067 https://reactome.org/PathwayBrowser/#/R-CFA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Canis familiaris 57305 R-CFA-5672965 https://reactome.org/PathwayBrowser/#/R-CFA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Canis familiaris 57305 R-CFA-5693967 https://reactome.org/PathwayBrowser/#/R-CFA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Canis familiaris 57305 R-CFA-5694137 https://reactome.org/PathwayBrowser/#/R-CFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Canis familiaris 57305 R-CFA-6797913 https://reactome.org/PathwayBrowser/#/R-CFA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Canis familiaris 57305 R-CFA-6798317 https://reactome.org/PathwayBrowser/#/R-CFA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Canis familiaris 57305 R-CFA-71249 https://reactome.org/PathwayBrowser/#/R-CFA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Canis familiaris 57305 R-CFA-71275 https://reactome.org/PathwayBrowser/#/R-CFA-71275 arginine + glycine => ornithine + guanidoacetate IEA Canis familiaris 57305 R-CFA-73814 https://reactome.org/PathwayBrowser/#/R-CFA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Canis familiaris 57305 R-CFA-8849878 https://reactome.org/PathwayBrowser/#/R-CFA-8849878 PSD-95 binds NMDA receptor IEA Canis familiaris 57305 R-CFA-8849881 https://reactome.org/PathwayBrowser/#/R-CFA-8849881 SALM2 associate with AMPA and NMDA receptors IEA Canis familiaris 57305 R-CFA-8849906 https://reactome.org/PathwayBrowser/#/R-CFA-8849906 SALM1 binds NMDA receptor IEA Canis familiaris 57305 R-CFA-8867370 https://reactome.org/PathwayBrowser/#/R-CFA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Canis familiaris 57305 R-CFA-904864 https://reactome.org/PathwayBrowser/#/R-CFA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Canis familiaris 57305 R-CFA-9750001 https://reactome.org/PathwayBrowser/#/R-CFA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Canis familiaris 57305 R-CFA-9753632 https://reactome.org/PathwayBrowser/#/R-CFA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Canis familiaris 57305 R-CFA-975389 https://reactome.org/PathwayBrowser/#/R-CFA-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Canis familiaris 57305 R-DDI-1247910 https://reactome.org/PathwayBrowser/#/R-DDI-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Dictyostelium discoideum 57305 R-DDI-174394 https://reactome.org/PathwayBrowser/#/R-DDI-174394 GSS:Mg2+ dimer synthesizes GSH IEA Dictyostelium discoideum 57305 R-DDI-189442 https://reactome.org/PathwayBrowser/#/R-DDI-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Dictyostelium discoideum 57305 R-DDI-200651 https://reactome.org/PathwayBrowser/#/R-DDI-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Dictyostelium discoideum 57305 R-DDI-200735 https://reactome.org/PathwayBrowser/#/R-DDI-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Dictyostelium discoideum 57305 R-DDI-375405 https://reactome.org/PathwayBrowser/#/R-DDI-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Dictyostelium discoideum 57305 R-DDI-375417 https://reactome.org/PathwayBrowser/#/R-DDI-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Dictyostelium discoideum 57305 R-DDI-389684 https://reactome.org/PathwayBrowser/#/R-DDI-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Dictyostelium discoideum 57305 R-DDI-389821 https://reactome.org/PathwayBrowser/#/R-DDI-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Dictyostelium discoideum 57305 R-DDI-5693967 https://reactome.org/PathwayBrowser/#/R-DDI-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Dictyostelium discoideum 57305 R-DDI-5694137 https://reactome.org/PathwayBrowser/#/R-DDI-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Dictyostelium discoideum 57305 R-DDI-71249 https://reactome.org/PathwayBrowser/#/R-DDI-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Dictyostelium discoideum 57305 R-DDI-73814 https://reactome.org/PathwayBrowser/#/R-DDI-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Dictyostelium discoideum 57305 R-DDI-8867370 https://reactome.org/PathwayBrowser/#/R-DDI-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Dictyostelium discoideum 57305 R-DDI-9753632 https://reactome.org/PathwayBrowser/#/R-DDI-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Dictyostelium discoideum 57305 R-DME-1247910 https://reactome.org/PathwayBrowser/#/R-DME-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Drosophila melanogaster 57305 R-DME-174394 https://reactome.org/PathwayBrowser/#/R-DME-174394 GSS:Mg2+ dimer synthesizes GSH IEA Drosophila melanogaster 57305 R-DME-189442 https://reactome.org/PathwayBrowser/#/R-DME-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Drosophila melanogaster 57305 R-DME-200651 https://reactome.org/PathwayBrowser/#/R-DME-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Drosophila melanogaster 57305 R-DME-200735 https://reactome.org/PathwayBrowser/#/R-DME-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Drosophila melanogaster 57305 R-DME-266012 https://reactome.org/PathwayBrowser/#/R-DME-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Drosophila melanogaster 57305 R-DME-351963 https://reactome.org/PathwayBrowser/#/R-DME-351963 SLC6A18 transports Gly from extracellular region to cytosol IEA Drosophila melanogaster 57305 R-DME-352108 https://reactome.org/PathwayBrowser/#/R-DME-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57305 R-DME-352182 https://reactome.org/PathwayBrowser/#/R-DME-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Drosophila melanogaster 57305 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57305 R-DME-375405 https://reactome.org/PathwayBrowser/#/R-DME-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Drosophila melanogaster 57305 R-DME-375417 https://reactome.org/PathwayBrowser/#/R-DME-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Drosophila melanogaster 57305 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57305 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57305 R-DME-376200 https://reactome.org/PathwayBrowser/#/R-DME-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Drosophila melanogaster 57305 R-DME-389684 https://reactome.org/PathwayBrowser/#/R-DME-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Drosophila melanogaster 57305 R-DME-389821 https://reactome.org/PathwayBrowser/#/R-DME-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Drosophila melanogaster 57305 R-DME-3928627 https://reactome.org/PathwayBrowser/#/R-DME-3928627 EPHB phosphorylates TIAM1 IEA Drosophila melanogaster 57305 R-DME-3928645 https://reactome.org/PathwayBrowser/#/R-DME-3928645 EPHB:NMDAR binds TIAM1 IEA Drosophila melanogaster 57305 R-DME-4093336 https://reactome.org/PathwayBrowser/#/R-DME-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 57305 R-DME-428625 https://reactome.org/PathwayBrowser/#/R-DME-428625 Vesicular inhibitory amino acid transport IEA Drosophila melanogaster 57305 R-DME-432164 https://reactome.org/PathwayBrowser/#/R-DME-432164 Ca2+ influx into the post-synaptic cell IEA Drosophila melanogaster 57305 R-DME-438037 https://reactome.org/PathwayBrowser/#/R-DME-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Drosophila melanogaster 57305 R-DME-444120 https://reactome.org/PathwayBrowser/#/R-DME-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57305 R-DME-5433067 https://reactome.org/PathwayBrowser/#/R-DME-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Drosophila melanogaster 57305 R-DME-5693967 https://reactome.org/PathwayBrowser/#/R-DME-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Drosophila melanogaster 57305 R-DME-6797913 https://reactome.org/PathwayBrowser/#/R-DME-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Drosophila melanogaster 57305 R-DME-6798317 https://reactome.org/PathwayBrowser/#/R-DME-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Drosophila melanogaster 57305 R-DME-71249 https://reactome.org/PathwayBrowser/#/R-DME-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Drosophila melanogaster 57305 R-DME-73814 https://reactome.org/PathwayBrowser/#/R-DME-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Drosophila melanogaster 57305 R-DME-8849878 https://reactome.org/PathwayBrowser/#/R-DME-8849878 PSD-95 binds NMDA receptor IEA Drosophila melanogaster 57305 R-DME-8849881 https://reactome.org/PathwayBrowser/#/R-DME-8849881 SALM2 associate with AMPA and NMDA receptors IEA Drosophila melanogaster 57305 R-DME-8849906 https://reactome.org/PathwayBrowser/#/R-DME-8849906 SALM1 binds NMDA receptor IEA Drosophila melanogaster 57305 R-DME-904864 https://reactome.org/PathwayBrowser/#/R-DME-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Drosophila melanogaster 57305 R-DME-9753632 https://reactome.org/PathwayBrowser/#/R-DME-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Drosophila melanogaster 57305 R-DME-975389 https://reactome.org/PathwayBrowser/#/R-DME-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Drosophila melanogaster 57305 R-DRE-1247910 https://reactome.org/PathwayBrowser/#/R-DRE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Danio rerio 57305 R-DRE-174394 https://reactome.org/PathwayBrowser/#/R-DRE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Danio rerio 57305 R-DRE-189442 https://reactome.org/PathwayBrowser/#/R-DRE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Danio rerio 57305 R-DRE-200651 https://reactome.org/PathwayBrowser/#/R-DRE-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Danio rerio 57305 R-DRE-200735 https://reactome.org/PathwayBrowser/#/R-DRE-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Danio rerio 57305 R-DRE-351963 https://reactome.org/PathwayBrowser/#/R-DRE-351963 SLC6A18 transports Gly from extracellular region to cytosol IEA Danio rerio 57305 R-DRE-352108 https://reactome.org/PathwayBrowser/#/R-DRE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Danio rerio 57305 R-DRE-352182 https://reactome.org/PathwayBrowser/#/R-DRE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Danio rerio 57305 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 57305 R-DRE-389684 https://reactome.org/PathwayBrowser/#/R-DRE-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Danio rerio 57305 R-DRE-389821 https://reactome.org/PathwayBrowser/#/R-DRE-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Danio rerio 57305 R-DRE-428625 https://reactome.org/PathwayBrowser/#/R-DRE-428625 Vesicular inhibitory amino acid transport IEA Danio rerio 57305 R-DRE-432164 https://reactome.org/PathwayBrowser/#/R-DRE-432164 Ca2+ influx into the post-synaptic cell IEA Danio rerio 57305 R-DRE-444120 https://reactome.org/PathwayBrowser/#/R-DRE-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Danio rerio 57305 R-DRE-5693967 https://reactome.org/PathwayBrowser/#/R-DRE-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Danio rerio 57305 R-DRE-5694137 https://reactome.org/PathwayBrowser/#/R-DRE-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Danio rerio 57305 R-DRE-6797913 https://reactome.org/PathwayBrowser/#/R-DRE-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Danio rerio 57305 R-DRE-6798317 https://reactome.org/PathwayBrowser/#/R-DRE-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Danio rerio 57305 R-DRE-71249 https://reactome.org/PathwayBrowser/#/R-DRE-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Danio rerio 57305 R-DRE-71275 https://reactome.org/PathwayBrowser/#/R-DRE-71275 arginine + glycine => ornithine + guanidoacetate IEA Danio rerio 57305 R-DRE-73814 https://reactome.org/PathwayBrowser/#/R-DRE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Danio rerio 57305 R-DRE-904864 https://reactome.org/PathwayBrowser/#/R-DRE-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Danio rerio 57305 R-DRE-9753632 https://reactome.org/PathwayBrowser/#/R-DRE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Danio rerio 57305 R-DRE-975389 https://reactome.org/PathwayBrowser/#/R-DRE-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Danio rerio 57305 R-GGA-1247910 https://reactome.org/PathwayBrowser/#/R-GGA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Gallus gallus 57305 R-GGA-159431 https://reactome.org/PathwayBrowser/#/R-GGA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Gallus gallus 57305 R-GGA-159566 https://reactome.org/PathwayBrowser/#/R-GGA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Gallus gallus 57305 R-GGA-159574 https://reactome.org/PathwayBrowser/#/R-GGA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Gallus gallus 57305 R-GGA-174394 https://reactome.org/PathwayBrowser/#/R-GGA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Gallus gallus 57305 R-GGA-189442 https://reactome.org/PathwayBrowser/#/R-GGA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Gallus gallus 57305 R-GGA-192312 https://reactome.org/PathwayBrowser/#/R-GGA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Gallus gallus 57305 R-GGA-193491 https://reactome.org/PathwayBrowser/#/R-GGA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Gallus gallus 57305 R-GGA-200651 https://reactome.org/PathwayBrowser/#/R-GGA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Gallus gallus 57305 R-GGA-200735 https://reactome.org/PathwayBrowser/#/R-GGA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Gallus gallus 57305 R-GGA-266012 https://reactome.org/PathwayBrowser/#/R-GGA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Gallus gallus 57305 R-GGA-351963 https://reactome.org/PathwayBrowser/#/R-GGA-351963 SLC6A18 transports Gly from extracellular region to cytosol IEA Gallus gallus 57305 R-GGA-352108 https://reactome.org/PathwayBrowser/#/R-GGA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Gallus gallus 57305 R-GGA-375405 https://reactome.org/PathwayBrowser/#/R-GGA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Gallus gallus 57305 R-GGA-375417 https://reactome.org/PathwayBrowser/#/R-GGA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Gallus gallus 57305 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 57305 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 57305 R-GGA-389684 https://reactome.org/PathwayBrowser/#/R-GGA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Gallus gallus 57305 R-GGA-389821 https://reactome.org/PathwayBrowser/#/R-GGA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Gallus gallus 57305 R-GGA-3928627 https://reactome.org/PathwayBrowser/#/R-GGA-3928627 EPHB phosphorylates TIAM1 IEA Gallus gallus 57305 R-GGA-3928645 https://reactome.org/PathwayBrowser/#/R-GGA-3928645 EPHB:NMDAR binds TIAM1 IEA Gallus gallus 57305 R-GGA-4093336 https://reactome.org/PathwayBrowser/#/R-GGA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 57305 R-GGA-419153 https://reactome.org/PathwayBrowser/#/R-GGA-419153 5-phosphoribosylamine + glycine + ATP <=> 5-phosphoribosylglycinamide (GAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 57305 R-GGA-421493 https://reactome.org/PathwayBrowser/#/R-GGA-421493 succinyl-CoA + glycine => delta-aminolevulinate + CoA SH + CO2 TAS Gallus gallus 57305 R-GGA-428625 https://reactome.org/PathwayBrowser/#/R-GGA-428625 Vesicular inhibitory amino acid transport IEA Gallus gallus 57305 R-GGA-432164 https://reactome.org/PathwayBrowser/#/R-GGA-432164 Ca2+ influx into the post-synaptic cell IEA Gallus gallus 57305 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus 57305 R-GGA-444120 https://reactome.org/PathwayBrowser/#/R-GGA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 57305 R-GGA-5433067 https://reactome.org/PathwayBrowser/#/R-GGA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Gallus gallus 57305 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus 57305 R-GGA-5693967 https://reactome.org/PathwayBrowser/#/R-GGA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Gallus gallus 57305 R-GGA-6797913 https://reactome.org/PathwayBrowser/#/R-GGA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Gallus gallus 57305 R-GGA-71249 https://reactome.org/PathwayBrowser/#/R-GGA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Gallus gallus 57305 R-GGA-71275 https://reactome.org/PathwayBrowser/#/R-GGA-71275 arginine + glycine => ornithine + guanidoacetate IEA Gallus gallus 57305 R-GGA-73814 https://reactome.org/PathwayBrowser/#/R-GGA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Gallus gallus 57305 R-GGA-8849881 https://reactome.org/PathwayBrowser/#/R-GGA-8849881 SALM2 associate with AMPA and NMDA receptors IEA Gallus gallus 57305 R-GGA-904864 https://reactome.org/PathwayBrowser/#/R-GGA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Gallus gallus 57305 R-GGA-9750001 https://reactome.org/PathwayBrowser/#/R-GGA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Gallus gallus 57305 R-GGA-9753632 https://reactome.org/PathwayBrowser/#/R-GGA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Gallus gallus 57305 R-GGA-975389 https://reactome.org/PathwayBrowser/#/R-GGA-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Gallus gallus 57305 R-HSA-1247910 https://reactome.org/PathwayBrowser/#/R-HSA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly TAS Homo sapiens 57305 R-HSA-159431 https://reactome.org/PathwayBrowser/#/R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine TAS Homo sapiens 57305 R-HSA-159566 https://reactome.org/PathwayBrowser/#/R-HSA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A TAS Homo sapiens 57305 R-HSA-159574 https://reactome.org/PathwayBrowser/#/R-HSA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA TAS Homo sapiens 57305 R-HSA-174394 https://reactome.org/PathwayBrowser/#/R-HSA-174394 GSS:Mg2+ dimer synthesizes GSH TAS Homo sapiens 57305 R-HSA-189442 https://reactome.org/PathwayBrowser/#/R-HSA-189442 ALAS condenses SUCC-CoA and Gly to form dALA TAS Homo sapiens 57305 R-HSA-192312 https://reactome.org/PathwayBrowser/#/R-HSA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate TAS Homo sapiens 57305 R-HSA-193491 https://reactome.org/PathwayBrowser/#/R-HSA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate TAS Homo sapiens 57305 R-HSA-200651 https://reactome.org/PathwayBrowser/#/R-HSA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine TAS Homo sapiens 57305 R-HSA-200735 https://reactome.org/PathwayBrowser/#/R-HSA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG TAS Homo sapiens 57305 R-HSA-2161868 https://reactome.org/PathwayBrowser/#/R-HSA-2161868 EXD4 is converted to EXE4 by DPEP TAS Homo sapiens 57305 R-HSA-2408544 https://reactome.org/PathwayBrowser/#/R-HSA-2408544 AdoSeMet is converted to AdeSeHCys by MetTrans(1) IEA Homo sapiens 57305 R-HSA-266012 https://reactome.org/PathwayBrowser/#/R-HSA-266012 LTD4 is converted to LTE4 by DPEP1/2 TAS Homo sapiens 57305 R-HSA-351963 https://reactome.org/PathwayBrowser/#/R-HSA-351963 SLC6A18 transports Gly from extracellular region to cytosol TAS Homo sapiens 57305 R-HSA-352108 https://reactome.org/PathwayBrowser/#/R-HSA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids TAS Homo sapiens 57305 R-HSA-352182 https://reactome.org/PathwayBrowser/#/R-HSA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine TAS Homo sapiens 57305 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 57305 R-HSA-375405 https://reactome.org/PathwayBrowser/#/R-HSA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol TAS Homo sapiens 57305 R-HSA-375417 https://reactome.org/PathwayBrowser/#/R-HSA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine TAS Homo sapiens 57305 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57305 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57305 R-HSA-376200 https://reactome.org/PathwayBrowser/#/R-HSA-376200 SLC7A10-mediated uptake of small neutral amino acids TAS Homo sapiens 57305 R-HSA-380048 https://reactome.org/PathwayBrowser/#/R-HSA-380048 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 57305 R-HSA-380240 https://reactome.org/PathwayBrowser/#/R-HSA-380240 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate TAS Homo sapiens 57305 R-HSA-389684 https://reactome.org/PathwayBrowser/#/R-HSA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] TAS Homo sapiens 57305 R-HSA-389821 https://reactome.org/PathwayBrowser/#/R-HSA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ TAS Homo sapiens 57305 R-HSA-3928583 https://reactome.org/PathwayBrowser/#/R-HSA-3928583 FYN phosphorylates NMDAR2B IEA Homo sapiens 57305 R-HSA-3928623 https://reactome.org/PathwayBrowser/#/R-HSA-3928623 EPHBs bind NMDARs IEA Homo sapiens 57305 R-HSA-3928627 https://reactome.org/PathwayBrowser/#/R-HSA-3928627 EPHB phosphorylates TIAM1 TAS Homo sapiens 57305 R-HSA-3928645 https://reactome.org/PathwayBrowser/#/R-HSA-3928645 EPHB:NMDAR binds TIAM1 TAS Homo sapiens 57305 R-HSA-4093336 https://reactome.org/PathwayBrowser/#/R-HSA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 57305 R-HSA-428625 https://reactome.org/PathwayBrowser/#/R-HSA-428625 Vesicular inhibitory amino acid transport TAS Homo sapiens 57305 R-HSA-432162 https://reactome.org/PathwayBrowser/#/R-HSA-432162 Unblocking of GRIN1:GRIN2 NMDA receptors IEA Homo sapiens 57305 R-HSA-432164 https://reactome.org/PathwayBrowser/#/R-HSA-432164 Ca2+ influx into the post-synaptic cell TAS Homo sapiens 57305 R-HSA-432172 https://reactome.org/PathwayBrowser/#/R-HSA-432172 Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor IEA Homo sapiens 57305 R-HSA-438037 https://reactome.org/PathwayBrowser/#/R-HSA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors TAS Homo sapiens 57305 R-HSA-442732 https://reactome.org/PathwayBrowser/#/R-HSA-442732 NMDA-activated RASGRF1 activates RAS IEA Homo sapiens 57305 R-HSA-442760 https://reactome.org/PathwayBrowser/#/R-HSA-442760 Activation of RasGRF IEA Homo sapiens 57305 R-HSA-444120 https://reactome.org/PathwayBrowser/#/R-HSA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 57305 R-HSA-445367 https://reactome.org/PathwayBrowser/#/R-HSA-445367 CaMKII binds activated NMDA receptor IEA Homo sapiens 57305 R-HSA-5433067 https://reactome.org/PathwayBrowser/#/R-HSA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG TAS Homo sapiens 57305 R-HSA-5602901 https://reactome.org/PathwayBrowser/#/R-HSA-5602901 Defective GSS does not synthesize GSH TAS Homo sapiens 57305 R-HSA-5653850 https://reactome.org/PathwayBrowser/#/R-HSA-5653850 Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol TAS Homo sapiens 57305 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57305 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57305 R-HSA-5659755 https://reactome.org/PathwayBrowser/#/R-HSA-5659755 Defective SLC6A18 does not transport Gly from extracellular region to cytosol TAS Homo sapiens 57305 R-HSA-5660840 https://reactome.org/PathwayBrowser/#/R-HSA-5660840 Defective SLC6A5 does not cotransport Gly, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 57305 R-HSA-5672965 https://reactome.org/PathwayBrowser/#/R-HSA-5672965 RAS GEFs promote RAS nucleotide exchange TAS Homo sapiens 57305 R-HSA-5693967 https://reactome.org/PathwayBrowser/#/R-HSA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly TAS Homo sapiens 57305 R-HSA-5694137 https://reactome.org/PathwayBrowser/#/R-HSA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser TAS Homo sapiens 57305 R-HSA-6797913 https://reactome.org/PathwayBrowser/#/R-HSA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly TAS Homo sapiens 57305 R-HSA-6798317 https://reactome.org/PathwayBrowser/#/R-HSA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC TAS Homo sapiens 57305 R-HSA-6798345 https://reactome.org/PathwayBrowser/#/R-HSA-6798345 PXLP-GCAT dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA TAS Homo sapiens 57305 R-HSA-71249 https://reactome.org/PathwayBrowser/#/R-HSA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly TAS Homo sapiens 57305 R-HSA-71275 https://reactome.org/PathwayBrowser/#/R-HSA-71275 arginine + glycine => ornithine + guanidoacetate TAS Homo sapiens 57305 R-HSA-73814 https://reactome.org/PathwayBrowser/#/R-HSA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi TAS Homo sapiens 57305 R-HSA-8849878 https://reactome.org/PathwayBrowser/#/R-HSA-8849878 PSD-95 binds NMDA receptor TAS Homo sapiens 57305 R-HSA-8849881 https://reactome.org/PathwayBrowser/#/R-HSA-8849881 SALM2 associate with AMPA and NMDA receptors TAS Homo sapiens 57305 R-HSA-8849906 https://reactome.org/PathwayBrowser/#/R-HSA-8849906 SALM1 binds NMDA receptor TAS Homo sapiens 57305 R-HSA-8867370 https://reactome.org/PathwayBrowser/#/R-HSA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin TAS Homo sapiens 57305 R-HSA-9026771 https://reactome.org/PathwayBrowser/#/R-HSA-9026771 DPEP hydrolyses MCTR2 to MCTR3 TAS Homo sapiens 57305 R-HSA-9026907 https://reactome.org/PathwayBrowser/#/R-HSA-9026907 GGT hydrolyses PCTR2 to PCTR3 TAS Homo sapiens 57305 R-HSA-9026916 https://reactome.org/PathwayBrowser/#/R-HSA-9026916 GGT hydrolyses RCTR2 to RCTR3 TAS Homo sapiens 57305 R-HSA-904864 https://reactome.org/PathwayBrowser/#/R-HSA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate TAS Homo sapiens 57305 R-HSA-9612085 https://reactome.org/PathwayBrowser/#/R-HSA-9612085 SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs IEA Homo sapiens 57305 R-HSA-9617326 https://reactome.org/PathwayBrowser/#/R-HSA-9617326 CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 IEA Homo sapiens 57305 R-HSA-9618750 https://reactome.org/PathwayBrowser/#/R-HSA-9618750 CaMKII phosphorylates AMPA receptor IEA Homo sapiens 57305 R-HSA-9750001 https://reactome.org/PathwayBrowser/#/R-HSA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid TAS Homo sapiens 57305 R-HSA-9753632 https://reactome.org/PathwayBrowser/#/R-HSA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly TAS Homo sapiens 57305 R-HSA-975389 https://reactome.org/PathwayBrowser/#/R-HSA-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol TAS Homo sapiens 57305 R-MMU-1247910 https://reactome.org/PathwayBrowser/#/R-MMU-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Mus musculus 57305 R-MMU-159431 https://reactome.org/PathwayBrowser/#/R-MMU-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Mus musculus 57305 R-MMU-159566 https://reactome.org/PathwayBrowser/#/R-MMU-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Mus musculus 57305 R-MMU-159574 https://reactome.org/PathwayBrowser/#/R-MMU-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Mus musculus 57305 R-MMU-174394 https://reactome.org/PathwayBrowser/#/R-MMU-174394 GSS:Mg2+ dimer synthesizes GSH IEA Mus musculus 57305 R-MMU-189442 https://reactome.org/PathwayBrowser/#/R-MMU-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Mus musculus 57305 R-MMU-192312 https://reactome.org/PathwayBrowser/#/R-MMU-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Mus musculus 57305 R-MMU-193491 https://reactome.org/PathwayBrowser/#/R-MMU-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Mus musculus 57305 R-MMU-200651 https://reactome.org/PathwayBrowser/#/R-MMU-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Mus musculus 57305 R-MMU-200735 https://reactome.org/PathwayBrowser/#/R-MMU-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Mus musculus 57305 R-MMU-266012 https://reactome.org/PathwayBrowser/#/R-MMU-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Mus musculus 57305 R-MMU-351963 https://reactome.org/PathwayBrowser/#/R-MMU-351963 SLC6A18 transports Gly from extracellular region to cytosol IEA Mus musculus 57305 R-MMU-352108 https://reactome.org/PathwayBrowser/#/R-MMU-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Mus musculus 57305 R-MMU-352182 https://reactome.org/PathwayBrowser/#/R-MMU-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Mus musculus 57305 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 57305 R-MMU-375405 https://reactome.org/PathwayBrowser/#/R-MMU-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Mus musculus 57305 R-MMU-375417 https://reactome.org/PathwayBrowser/#/R-MMU-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Mus musculus 57305 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 57305 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 57305 R-MMU-376200 https://reactome.org/PathwayBrowser/#/R-MMU-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Mus musculus 57305 R-MMU-389684 https://reactome.org/PathwayBrowser/#/R-MMU-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Mus musculus 57305 R-MMU-389821 https://reactome.org/PathwayBrowser/#/R-MMU-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Mus musculus 57305 R-MMU-3928627 https://reactome.org/PathwayBrowser/#/R-MMU-3928627 EPHB phosphorylates TIAM1 IEA Mus musculus 57305 R-MMU-3928645 https://reactome.org/PathwayBrowser/#/R-MMU-3928645 EPHB:NMDAR binds TIAM1 IEA Mus musculus 57305 R-MMU-4093336 https://reactome.org/PathwayBrowser/#/R-MMU-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 57305 R-MMU-428625 https://reactome.org/PathwayBrowser/#/R-MMU-428625 Vesicular inhibitory amino acid transport IEA Mus musculus 57305 R-MMU-432164 https://reactome.org/PathwayBrowser/#/R-MMU-432164 Ca2+ influx into the post-synaptic cell IEA Mus musculus 57305 R-MMU-438037 https://reactome.org/PathwayBrowser/#/R-MMU-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Mus musculus 57305 R-MMU-444120 https://reactome.org/PathwayBrowser/#/R-MMU-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 57305 R-MMU-5433067 https://reactome.org/PathwayBrowser/#/R-MMU-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Mus musculus 57305 R-MMU-5672965 https://reactome.org/PathwayBrowser/#/R-MMU-5672965 RAS GEFs promote RAS nucleotide exchange IEA Mus musculus 57305 R-MMU-5693967 https://reactome.org/PathwayBrowser/#/R-MMU-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Mus musculus 57305 R-MMU-5694137 https://reactome.org/PathwayBrowser/#/R-MMU-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Mus musculus 57305 R-MMU-6797913 https://reactome.org/PathwayBrowser/#/R-MMU-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Mus musculus 57305 R-MMU-6798317 https://reactome.org/PathwayBrowser/#/R-MMU-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Mus musculus 57305 R-MMU-71249 https://reactome.org/PathwayBrowser/#/R-MMU-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Mus musculus 57305 R-MMU-71275 https://reactome.org/PathwayBrowser/#/R-MMU-71275 arginine + glycine => ornithine + guanidoacetate IEA Mus musculus 57305 R-MMU-73814 https://reactome.org/PathwayBrowser/#/R-MMU-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Mus musculus 57305 R-MMU-8849878 https://reactome.org/PathwayBrowser/#/R-MMU-8849878 PSD-95 binds NMDA receptor IEA Mus musculus 57305 R-MMU-8849881 https://reactome.org/PathwayBrowser/#/R-MMU-8849881 SALM2 associate with AMPA and NMDA receptors IEA Mus musculus 57305 R-MMU-8849906 https://reactome.org/PathwayBrowser/#/R-MMU-8849906 SALM1 binds NMDA receptor IEA Mus musculus 57305 R-MMU-8867370 https://reactome.org/PathwayBrowser/#/R-MMU-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Mus musculus 57305 R-MMU-904864 https://reactome.org/PathwayBrowser/#/R-MMU-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Mus musculus 57305 R-MMU-9750001 https://reactome.org/PathwayBrowser/#/R-MMU-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Mus musculus 57305 R-MMU-9753632 https://reactome.org/PathwayBrowser/#/R-MMU-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Mus musculus 57305 R-MMU-975389 https://reactome.org/PathwayBrowser/#/R-MMU-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Mus musculus 57305 R-PFA-174394 https://reactome.org/PathwayBrowser/#/R-PFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Plasmodium falciparum 57305 R-PFA-189442 https://reactome.org/PathwayBrowser/#/R-PFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Plasmodium falciparum 57305 R-PFA-200651 https://reactome.org/PathwayBrowser/#/R-PFA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Plasmodium falciparum 57305 R-PFA-200735 https://reactome.org/PathwayBrowser/#/R-PFA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Plasmodium falciparum 57305 R-PFA-351963 https://reactome.org/PathwayBrowser/#/R-PFA-351963 SLC6A18 transports Gly from extracellular region to cytosol IEA Plasmodium falciparum 57305 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57305 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57305 R-PFA-444120 https://reactome.org/PathwayBrowser/#/R-PFA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57305 R-PFA-5694137 https://reactome.org/PathwayBrowser/#/R-PFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Plasmodium falciparum 57305 R-PFA-71249 https://reactome.org/PathwayBrowser/#/R-PFA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Plasmodium falciparum 57305 R-RNO-1247910 https://reactome.org/PathwayBrowser/#/R-RNO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Rattus norvegicus 57305 R-RNO-159431 https://reactome.org/PathwayBrowser/#/R-RNO-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Rattus norvegicus 57305 R-RNO-159566 https://reactome.org/PathwayBrowser/#/R-RNO-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Rattus norvegicus 57305 R-RNO-159574 https://reactome.org/PathwayBrowser/#/R-RNO-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Rattus norvegicus 57305 R-RNO-174394 https://reactome.org/PathwayBrowser/#/R-RNO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Rattus norvegicus 57305 R-RNO-189442 https://reactome.org/PathwayBrowser/#/R-RNO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Rattus norvegicus 57305 R-RNO-192312 https://reactome.org/PathwayBrowser/#/R-RNO-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Rattus norvegicus 57305 R-RNO-193491 https://reactome.org/PathwayBrowser/#/R-RNO-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Rattus norvegicus 57305 R-RNO-200651 https://reactome.org/PathwayBrowser/#/R-RNO-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Rattus norvegicus 57305 R-RNO-200735 https://reactome.org/PathwayBrowser/#/R-RNO-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Rattus norvegicus 57305 R-RNO-2408545 https://reactome.org/PathwayBrowser/#/R-RNO-2408545 AdoSeMet is converted to AdeSeHCys by MetTrans(2) TAS Rattus norvegicus 57305 R-RNO-266012 https://reactome.org/PathwayBrowser/#/R-RNO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Rattus norvegicus 57305 R-RNO-351963 https://reactome.org/PathwayBrowser/#/R-RNO-351963 SLC6A18 transports Gly from extracellular region to cytosol IEA Rattus norvegicus 57305 R-RNO-352108 https://reactome.org/PathwayBrowser/#/R-RNO-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Rattus norvegicus 57305 R-RNO-352182 https://reactome.org/PathwayBrowser/#/R-RNO-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Rattus norvegicus 57305 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 57305 R-RNO-375405 https://reactome.org/PathwayBrowser/#/R-RNO-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Rattus norvegicus 57305 R-RNO-375417 https://reactome.org/PathwayBrowser/#/R-RNO-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Rattus norvegicus 57305 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 57305 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 57305 R-RNO-376200 https://reactome.org/PathwayBrowser/#/R-RNO-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Rattus norvegicus 57305 R-RNO-389684 https://reactome.org/PathwayBrowser/#/R-RNO-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Rattus norvegicus 57305 R-RNO-389821 https://reactome.org/PathwayBrowser/#/R-RNO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Rattus norvegicus 57305 R-RNO-3928627 https://reactome.org/PathwayBrowser/#/R-RNO-3928627 EPHB phosphorylates TIAM1 IEA Rattus norvegicus 57305 R-RNO-3928645 https://reactome.org/PathwayBrowser/#/R-RNO-3928645 EPHB:NMDAR binds TIAM1 IEA Rattus norvegicus 57305 R-RNO-4093336 https://reactome.org/PathwayBrowser/#/R-RNO-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 57305 R-RNO-428625 https://reactome.org/PathwayBrowser/#/R-RNO-428625 Vesicular inhibitory amino acid transport IEA Rattus norvegicus 57305 R-RNO-432164 https://reactome.org/PathwayBrowser/#/R-RNO-432164 Ca2+ influx into the post-synaptic cell IEA Rattus norvegicus 57305 R-RNO-438037 https://reactome.org/PathwayBrowser/#/R-RNO-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Rattus norvegicus 57305 R-RNO-444120 https://reactome.org/PathwayBrowser/#/R-RNO-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 57305 R-RNO-5433067 https://reactome.org/PathwayBrowser/#/R-RNO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Rattus norvegicus 57305 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus 57305 R-RNO-5693967 https://reactome.org/PathwayBrowser/#/R-RNO-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Rattus norvegicus 57305 R-RNO-5694137 https://reactome.org/PathwayBrowser/#/R-RNO-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Rattus norvegicus 57305 R-RNO-6797913 https://reactome.org/PathwayBrowser/#/R-RNO-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Rattus norvegicus 57305 R-RNO-6798317 https://reactome.org/PathwayBrowser/#/R-RNO-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Rattus norvegicus 57305 R-RNO-71249 https://reactome.org/PathwayBrowser/#/R-RNO-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Rattus norvegicus 57305 R-RNO-71275 https://reactome.org/PathwayBrowser/#/R-RNO-71275 arginine + glycine => ornithine + guanidoacetate IEA Rattus norvegicus 57305 R-RNO-73814 https://reactome.org/PathwayBrowser/#/R-RNO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Rattus norvegicus 57305 R-RNO-8849878 https://reactome.org/PathwayBrowser/#/R-RNO-8849878 PSD-95 binds NMDA receptor IEA Rattus norvegicus 57305 R-RNO-8849881 https://reactome.org/PathwayBrowser/#/R-RNO-8849881 SALM2 associate with AMPA and NMDA receptors IEA Rattus norvegicus 57305 R-RNO-8849906 https://reactome.org/PathwayBrowser/#/R-RNO-8849906 SALM1 binds NMDA receptor IEA Rattus norvegicus 57305 R-RNO-8867370 https://reactome.org/PathwayBrowser/#/R-RNO-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Rattus norvegicus 57305 R-RNO-904864 https://reactome.org/PathwayBrowser/#/R-RNO-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Rattus norvegicus 57305 R-RNO-9612145 https://reactome.org/PathwayBrowser/#/R-RNO-9612145 Src phosphorylates GluN2 (Grin2) subunits of NMDARs TAS Rattus norvegicus 57305 R-RNO-9614350 https://reactome.org/PathwayBrowser/#/R-RNO-9614350 Glycine and glutamate ligands bind Grin1:Grin2a NMDA receptor TAS Rattus norvegicus 57305 R-RNO-9614351 https://reactome.org/PathwayBrowser/#/R-RNO-9614351 Unblocking of Grin1:Grin2 NMDA receptors TAS Rattus norvegicus 57305 R-RNO-9617322 https://reactome.org/PathwayBrowser/#/R-RNO-9617322 Calm1:4xCa2+ binds GluN1:GluN2 (Grin1:Grin2) NMDA receptors and displaces Actn2 TAS Rattus norvegicus 57305 R-RNO-9618659 https://reactome.org/PathwayBrowser/#/R-RNO-9618659 CaMKII binds activated GluN1:GluN2B (Grin1:Grin2b) NMDA receptor TAS Rattus norvegicus 57305 R-RNO-9750001 https://reactome.org/PathwayBrowser/#/R-RNO-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Rattus norvegicus 57305 R-RNO-9753632 https://reactome.org/PathwayBrowser/#/R-RNO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Rattus norvegicus 57305 R-RNO-975389 https://reactome.org/PathwayBrowser/#/R-RNO-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Rattus norvegicus 57305 R-SCE-1247910 https://reactome.org/PathwayBrowser/#/R-SCE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Saccharomyces cerevisiae 57305 R-SCE-174394 https://reactome.org/PathwayBrowser/#/R-SCE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Saccharomyces cerevisiae 57305 R-SCE-189442 https://reactome.org/PathwayBrowser/#/R-SCE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Saccharomyces cerevisiae 57305 R-SCE-352108 https://reactome.org/PathwayBrowser/#/R-SCE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 57305 R-SCE-352182 https://reactome.org/PathwayBrowser/#/R-SCE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Saccharomyces cerevisiae 57305 R-SCE-375405 https://reactome.org/PathwayBrowser/#/R-SCE-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 57305 R-SCE-375417 https://reactome.org/PathwayBrowser/#/R-SCE-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Saccharomyces cerevisiae 57305 R-SCE-428625 https://reactome.org/PathwayBrowser/#/R-SCE-428625 Vesicular inhibitory amino acid transport IEA Saccharomyces cerevisiae 57305 R-SCE-5693967 https://reactome.org/PathwayBrowser/#/R-SCE-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Saccharomyces cerevisiae 57305 R-SCE-73814 https://reactome.org/PathwayBrowser/#/R-SCE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Saccharomyces cerevisiae 57305 R-SCE-9753632 https://reactome.org/PathwayBrowser/#/R-SCE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Saccharomyces cerevisiae 57305 R-SPO-1247910 https://reactome.org/PathwayBrowser/#/R-SPO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Schizosaccharomyces pombe 57305 R-SPO-174394 https://reactome.org/PathwayBrowser/#/R-SPO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Schizosaccharomyces pombe 57305 R-SPO-189442 https://reactome.org/PathwayBrowser/#/R-SPO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Schizosaccharomyces pombe 57305 R-SPO-266012 https://reactome.org/PathwayBrowser/#/R-SPO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Schizosaccharomyces pombe 57305 R-SPO-389821 https://reactome.org/PathwayBrowser/#/R-SPO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Schizosaccharomyces pombe 57305 R-SPO-5433067 https://reactome.org/PathwayBrowser/#/R-SPO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Schizosaccharomyces pombe 57305 R-SPO-5693967 https://reactome.org/PathwayBrowser/#/R-SPO-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Schizosaccharomyces pombe 57305 R-SPO-73814 https://reactome.org/PathwayBrowser/#/R-SPO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Schizosaccharomyces pombe 57305 R-SPO-904864 https://reactome.org/PathwayBrowser/#/R-SPO-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Schizosaccharomyces pombe 57305 R-SPO-9753632 https://reactome.org/PathwayBrowser/#/R-SPO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Schizosaccharomyces pombe 57305 R-SSC-1247910 https://reactome.org/PathwayBrowser/#/R-SSC-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Sus scrofa 57305 R-SSC-159431 https://reactome.org/PathwayBrowser/#/R-SSC-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Sus scrofa 57305 R-SSC-159566 https://reactome.org/PathwayBrowser/#/R-SSC-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Sus scrofa 57305 R-SSC-159574 https://reactome.org/PathwayBrowser/#/R-SSC-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Sus scrofa 57305 R-SSC-174394 https://reactome.org/PathwayBrowser/#/R-SSC-174394 GSS:Mg2+ dimer synthesizes GSH IEA Sus scrofa 57305 R-SSC-189442 https://reactome.org/PathwayBrowser/#/R-SSC-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Sus scrofa 57305 R-SSC-192312 https://reactome.org/PathwayBrowser/#/R-SSC-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Sus scrofa 57305 R-SSC-193491 https://reactome.org/PathwayBrowser/#/R-SSC-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Sus scrofa 57305 R-SSC-200651 https://reactome.org/PathwayBrowser/#/R-SSC-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Sus scrofa 57305 R-SSC-200735 https://reactome.org/PathwayBrowser/#/R-SSC-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Sus scrofa 57305 R-SSC-266012 https://reactome.org/PathwayBrowser/#/R-SSC-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Sus scrofa 57305 R-SSC-351963 https://reactome.org/PathwayBrowser/#/R-SSC-351963 SLC6A18 transports Gly from extracellular region to cytosol IEA Sus scrofa 57305 R-SSC-352108 https://reactome.org/PathwayBrowser/#/R-SSC-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Sus scrofa 57305 R-SSC-352182 https://reactome.org/PathwayBrowser/#/R-SSC-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Sus scrofa 57305 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 57305 R-SSC-375405 https://reactome.org/PathwayBrowser/#/R-SSC-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Sus scrofa 57305 R-SSC-375417 https://reactome.org/PathwayBrowser/#/R-SSC-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Sus scrofa 57305 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 57305 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 57305 R-SSC-376200 https://reactome.org/PathwayBrowser/#/R-SSC-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Sus scrofa 57305 R-SSC-389684 https://reactome.org/PathwayBrowser/#/R-SSC-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Sus scrofa 57305 R-SSC-389821 https://reactome.org/PathwayBrowser/#/R-SSC-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Sus scrofa 57305 R-SSC-3928627 https://reactome.org/PathwayBrowser/#/R-SSC-3928627 EPHB phosphorylates TIAM1 IEA Sus scrofa 57305 R-SSC-3928645 https://reactome.org/PathwayBrowser/#/R-SSC-3928645 EPHB:NMDAR binds TIAM1 IEA Sus scrofa 57305 R-SSC-4093336 https://reactome.org/PathwayBrowser/#/R-SSC-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa 57305 R-SSC-428625 https://reactome.org/PathwayBrowser/#/R-SSC-428625 Vesicular inhibitory amino acid transport IEA Sus scrofa 57305 R-SSC-432164 https://reactome.org/PathwayBrowser/#/R-SSC-432164 Ca2+ influx into the post-synaptic cell IEA Sus scrofa 57305 R-SSC-438037 https://reactome.org/PathwayBrowser/#/R-SSC-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Sus scrofa 57305 R-SSC-444120 https://reactome.org/PathwayBrowser/#/R-SSC-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 57305 R-SSC-5433067 https://reactome.org/PathwayBrowser/#/R-SSC-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Sus scrofa 57305 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa 57305 R-SSC-5693967 https://reactome.org/PathwayBrowser/#/R-SSC-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Sus scrofa 57305 R-SSC-5694137 https://reactome.org/PathwayBrowser/#/R-SSC-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Sus scrofa 57305 R-SSC-6797913 https://reactome.org/PathwayBrowser/#/R-SSC-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Sus scrofa 57305 R-SSC-6798317 https://reactome.org/PathwayBrowser/#/R-SSC-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Sus scrofa 57305 R-SSC-71249 https://reactome.org/PathwayBrowser/#/R-SSC-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Sus scrofa 57305 R-SSC-71275 https://reactome.org/PathwayBrowser/#/R-SSC-71275 arginine + glycine => ornithine + guanidoacetate IEA Sus scrofa 57305 R-SSC-73814 https://reactome.org/PathwayBrowser/#/R-SSC-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Sus scrofa 57305 R-SSC-8849878 https://reactome.org/PathwayBrowser/#/R-SSC-8849878 PSD-95 binds NMDA receptor IEA Sus scrofa 57305 R-SSC-8849906 https://reactome.org/PathwayBrowser/#/R-SSC-8849906 SALM1 binds NMDA receptor IEA Sus scrofa 57305 R-SSC-8867370 https://reactome.org/PathwayBrowser/#/R-SSC-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Sus scrofa 57305 R-SSC-904864 https://reactome.org/PathwayBrowser/#/R-SSC-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Sus scrofa 57305 R-SSC-9750001 https://reactome.org/PathwayBrowser/#/R-SSC-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Sus scrofa 57305 R-SSC-9753632 https://reactome.org/PathwayBrowser/#/R-SSC-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Sus scrofa 57305 R-SSC-975389 https://reactome.org/PathwayBrowser/#/R-SSC-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Sus scrofa 57305 R-XTR-1247910 https://reactome.org/PathwayBrowser/#/R-XTR-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Xenopus tropicalis 57305 R-XTR-159431 https://reactome.org/PathwayBrowser/#/R-XTR-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Xenopus tropicalis 57305 R-XTR-159566 https://reactome.org/PathwayBrowser/#/R-XTR-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Xenopus tropicalis 57305 R-XTR-159574 https://reactome.org/PathwayBrowser/#/R-XTR-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Xenopus tropicalis 57305 R-XTR-189442 https://reactome.org/PathwayBrowser/#/R-XTR-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Xenopus tropicalis 57305 R-XTR-192312 https://reactome.org/PathwayBrowser/#/R-XTR-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Xenopus tropicalis 57305 R-XTR-193491 https://reactome.org/PathwayBrowser/#/R-XTR-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Xenopus tropicalis 57305 R-XTR-200651 https://reactome.org/PathwayBrowser/#/R-XTR-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Xenopus tropicalis 57305 R-XTR-200735 https://reactome.org/PathwayBrowser/#/R-XTR-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Xenopus tropicalis 57305 R-XTR-352108 https://reactome.org/PathwayBrowser/#/R-XTR-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57305 R-XTR-352182 https://reactome.org/PathwayBrowser/#/R-XTR-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Xenopus tropicalis 57305 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57305 R-XTR-375405 https://reactome.org/PathwayBrowser/#/R-XTR-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Xenopus tropicalis 57305 R-XTR-375417 https://reactome.org/PathwayBrowser/#/R-XTR-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Xenopus tropicalis 57305 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57305 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57305 R-XTR-376200 https://reactome.org/PathwayBrowser/#/R-XTR-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Xenopus tropicalis 57305 R-XTR-389684 https://reactome.org/PathwayBrowser/#/R-XTR-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Xenopus tropicalis 57305 R-XTR-389821 https://reactome.org/PathwayBrowser/#/R-XTR-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Xenopus tropicalis 57305 R-XTR-3928627 https://reactome.org/PathwayBrowser/#/R-XTR-3928627 EPHB phosphorylates TIAM1 IEA Xenopus tropicalis 57305 R-XTR-3928645 https://reactome.org/PathwayBrowser/#/R-XTR-3928645 EPHB:NMDAR binds TIAM1 IEA Xenopus tropicalis 57305 R-XTR-4093336 https://reactome.org/PathwayBrowser/#/R-XTR-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Xenopus tropicalis 57305 R-XTR-432164 https://reactome.org/PathwayBrowser/#/R-XTR-432164 Ca2+ influx into the post-synaptic cell IEA Xenopus tropicalis 57305 R-XTR-444120 https://reactome.org/PathwayBrowser/#/R-XTR-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57305 R-XTR-5694137 https://reactome.org/PathwayBrowser/#/R-XTR-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Xenopus tropicalis 57305 R-XTR-6798317 https://reactome.org/PathwayBrowser/#/R-XTR-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Xenopus tropicalis 57305 R-XTR-71249 https://reactome.org/PathwayBrowser/#/R-XTR-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Xenopus tropicalis 57305 R-XTR-71275 https://reactome.org/PathwayBrowser/#/R-XTR-71275 arginine + glycine => ornithine + guanidoacetate IEA Xenopus tropicalis 57305 R-XTR-73814 https://reactome.org/PathwayBrowser/#/R-XTR-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Xenopus tropicalis 57305 R-XTR-8849881 https://reactome.org/PathwayBrowser/#/R-XTR-8849881 SALM2 associate with AMPA and NMDA receptors IEA Xenopus tropicalis 57305 R-XTR-8867370 https://reactome.org/PathwayBrowser/#/R-XTR-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Xenopus tropicalis 57305 R-XTR-904864 https://reactome.org/PathwayBrowser/#/R-XTR-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Xenopus tropicalis 57305 R-XTR-9750001 https://reactome.org/PathwayBrowser/#/R-XTR-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Xenopus tropicalis 57305 R-XTR-9753632 https://reactome.org/PathwayBrowser/#/R-XTR-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Xenopus tropicalis 57305 R-XTR-975389 https://reactome.org/PathwayBrowser/#/R-XTR-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Xenopus tropicalis 57306 R-BTA-189423 https://reactome.org/PathwayBrowser/#/R-BTA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Bos taurus 57306 R-BTA-189465 https://reactome.org/PathwayBrowser/#/R-BTA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Bos taurus 57306 R-CEL-189465 https://reactome.org/PathwayBrowser/#/R-CEL-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Caenorhabditis elegans 57306 R-CFA-189423 https://reactome.org/PathwayBrowser/#/R-CFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Canis familiaris 57306 R-CFA-189465 https://reactome.org/PathwayBrowser/#/R-CFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Canis familiaris 57306 R-DDI-189423 https://reactome.org/PathwayBrowser/#/R-DDI-189423 PPO oxidises PPGEN9 to PRIN9 IEA Dictyostelium discoideum 57306 R-DDI-189465 https://reactome.org/PathwayBrowser/#/R-DDI-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Dictyostelium discoideum 57306 R-DME-189423 https://reactome.org/PathwayBrowser/#/R-DME-189423 PPO oxidises PPGEN9 to PRIN9 IEA Drosophila melanogaster 57306 R-DME-189465 https://reactome.org/PathwayBrowser/#/R-DME-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Drosophila melanogaster 57306 R-DRE-189423 https://reactome.org/PathwayBrowser/#/R-DRE-189423 PPO oxidises PPGEN9 to PRIN9 IEA Danio rerio 57306 R-DRE-189465 https://reactome.org/PathwayBrowser/#/R-DRE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Danio rerio 57306 R-GGA-189423 https://reactome.org/PathwayBrowser/#/R-GGA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Gallus gallus 57306 R-GGA-189465 https://reactome.org/PathwayBrowser/#/R-GGA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Gallus gallus 57306 R-GGA-421447 https://reactome.org/PathwayBrowser/#/R-GGA-421447 protoporphyrin IX + Fe++ => heme + 2 H+ TAS Gallus gallus 57306 R-GGA-421452 https://reactome.org/PathwayBrowser/#/R-GGA-421452 2 protoporphyrinogen IX + 3 O2 => 2 protoporphyrin IX + 6 H2O IEA Gallus gallus 57306 R-GGA-421454 https://reactome.org/PathwayBrowser/#/R-GGA-421454 Transport of protoporphyrin IX from the mitochondrial intermembrane space into the mitochondrial matrix TAS Gallus gallus 57306 R-HSA-189423 https://reactome.org/PathwayBrowser/#/R-HSA-189423 PPO oxidises PPGEN9 to PRIN9 TAS Homo sapiens 57306 R-HSA-189457 https://reactome.org/PathwayBrowser/#/R-HSA-189457 Mitochondrial intermembrane PRIN9 translocates to mitochondrial matrix TAS Homo sapiens 57306 R-HSA-189465 https://reactome.org/PathwayBrowser/#/R-HSA-189465 FECH binds Fe2+ to PRIN9 to form heme TAS Homo sapiens 57306 R-MMU-189423 https://reactome.org/PathwayBrowser/#/R-MMU-189423 PPO oxidises PPGEN9 to PRIN9 IEA Mus musculus 57306 R-MMU-189465 https://reactome.org/PathwayBrowser/#/R-MMU-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Mus musculus 57306 R-PFA-189423 https://reactome.org/PathwayBrowser/#/R-PFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Plasmodium falciparum 57306 R-PFA-189465 https://reactome.org/PathwayBrowser/#/R-PFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Plasmodium falciparum 57306 R-RNO-189423 https://reactome.org/PathwayBrowser/#/R-RNO-189423 PPO oxidises PPGEN9 to PRIN9 IEA Rattus norvegicus 57306 R-RNO-189465 https://reactome.org/PathwayBrowser/#/R-RNO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Rattus norvegicus 57306 R-SCE-189423 https://reactome.org/PathwayBrowser/#/R-SCE-189423 PPO oxidises PPGEN9 to PRIN9 IEA Saccharomyces cerevisiae 57306 R-SCE-189465 https://reactome.org/PathwayBrowser/#/R-SCE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Saccharomyces cerevisiae 57306 R-SPO-189423 https://reactome.org/PathwayBrowser/#/R-SPO-189423 PPO oxidises PPGEN9 to PRIN9 IEA Schizosaccharomyces pombe 57306 R-SPO-189465 https://reactome.org/PathwayBrowser/#/R-SPO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Schizosaccharomyces pombe 57306 R-SSC-189423 https://reactome.org/PathwayBrowser/#/R-SSC-189423 PPO oxidises PPGEN9 to PRIN9 IEA Sus scrofa 57306 R-SSC-189465 https://reactome.org/PathwayBrowser/#/R-SSC-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Sus scrofa 57306 R-XTR-189423 https://reactome.org/PathwayBrowser/#/R-XTR-189423 PPO oxidises PPGEN9 to PRIN9 IEA Xenopus tropicalis 57307 R-BTA-189421 https://reactome.org/PathwayBrowser/#/R-BTA-189421 CPO transforms COPRO3 to PPGEN9 IEA Bos taurus 57307 R-BTA-189423 https://reactome.org/PathwayBrowser/#/R-BTA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Bos taurus 57307 R-CFA-189421 https://reactome.org/PathwayBrowser/#/R-CFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Canis familiaris 57307 R-CFA-189423 https://reactome.org/PathwayBrowser/#/R-CFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Canis familiaris 57307 R-DDI-189421 https://reactome.org/PathwayBrowser/#/R-DDI-189421 CPO transforms COPRO3 to PPGEN9 IEA Dictyostelium discoideum 57307 R-DDI-189423 https://reactome.org/PathwayBrowser/#/R-DDI-189423 PPO oxidises PPGEN9 to PRIN9 IEA Dictyostelium discoideum 57307 R-DME-189421 https://reactome.org/PathwayBrowser/#/R-DME-189421 CPO transforms COPRO3 to PPGEN9 IEA Drosophila melanogaster 57307 R-DME-189423 https://reactome.org/PathwayBrowser/#/R-DME-189423 PPO oxidises PPGEN9 to PRIN9 IEA Drosophila melanogaster 57307 R-DRE-189421 https://reactome.org/PathwayBrowser/#/R-DRE-189421 CPO transforms COPRO3 to PPGEN9 IEA Danio rerio 57307 R-DRE-189423 https://reactome.org/PathwayBrowser/#/R-DRE-189423 PPO oxidises PPGEN9 to PRIN9 IEA Danio rerio 57307 R-GGA-189421 https://reactome.org/PathwayBrowser/#/R-GGA-189421 CPO transforms COPRO3 to PPGEN9 IEA Gallus gallus 57307 R-GGA-189423 https://reactome.org/PathwayBrowser/#/R-GGA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Gallus gallus 57307 R-GGA-421452 https://reactome.org/PathwayBrowser/#/R-GGA-421452 2 protoporphyrinogen IX + 3 O2 => 2 protoporphyrin IX + 6 H2O IEA Gallus gallus 57307 R-GGA-421478 https://reactome.org/PathwayBrowser/#/R-GGA-421478 coproporphyrinogen III + 2 O2 => protoporphyrinogen IX + 2 H2O2 + 2 CO2 IEA Gallus gallus 57307 R-HSA-189421 https://reactome.org/PathwayBrowser/#/R-HSA-189421 CPO transforms COPRO3 to PPGEN9 TAS Homo sapiens 57307 R-HSA-189423 https://reactome.org/PathwayBrowser/#/R-HSA-189423 PPO oxidises PPGEN9 to PRIN9 TAS Homo sapiens 57307 R-MMU-189421 https://reactome.org/PathwayBrowser/#/R-MMU-189421 CPO transforms COPRO3 to PPGEN9 IEA Mus musculus 57307 R-MMU-189423 https://reactome.org/PathwayBrowser/#/R-MMU-189423 PPO oxidises PPGEN9 to PRIN9 IEA Mus musculus 57307 R-PFA-189421 https://reactome.org/PathwayBrowser/#/R-PFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Plasmodium falciparum 57307 R-PFA-189423 https://reactome.org/PathwayBrowser/#/R-PFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Plasmodium falciparum 57307 R-RNO-189421 https://reactome.org/PathwayBrowser/#/R-RNO-189421 CPO transforms COPRO3 to PPGEN9 IEA Rattus norvegicus 57307 R-RNO-189423 https://reactome.org/PathwayBrowser/#/R-RNO-189423 PPO oxidises PPGEN9 to PRIN9 IEA Rattus norvegicus 57307 R-SCE-189421 https://reactome.org/PathwayBrowser/#/R-SCE-189421 CPO transforms COPRO3 to PPGEN9 IEA Saccharomyces cerevisiae 57307 R-SCE-189423 https://reactome.org/PathwayBrowser/#/R-SCE-189423 PPO oxidises PPGEN9 to PRIN9 IEA Saccharomyces cerevisiae 57307 R-SPO-189421 https://reactome.org/PathwayBrowser/#/R-SPO-189421 CPO transforms COPRO3 to PPGEN9 IEA Schizosaccharomyces pombe 57307 R-SPO-189423 https://reactome.org/PathwayBrowser/#/R-SPO-189423 PPO oxidises PPGEN9 to PRIN9 IEA Schizosaccharomyces pombe 57307 R-SSC-189421 https://reactome.org/PathwayBrowser/#/R-SSC-189421 CPO transforms COPRO3 to PPGEN9 IEA Sus scrofa 57307 R-SSC-189423 https://reactome.org/PathwayBrowser/#/R-SSC-189423 PPO oxidises PPGEN9 to PRIN9 IEA Sus scrofa 57307 R-XTR-189421 https://reactome.org/PathwayBrowser/#/R-XTR-189421 CPO transforms COPRO3 to PPGEN9 IEA Xenopus tropicalis 57307 R-XTR-189423 https://reactome.org/PathwayBrowser/#/R-XTR-189423 PPO oxidises PPGEN9 to PRIN9 IEA Xenopus tropicalis 57308 R-BTA-189425 https://reactome.org/PathwayBrowser/#/R-BTA-189425 UROD decarboxylates URO3 to COPRO3 IEA Bos taurus 57308 R-BTA-189488 https://reactome.org/PathwayBrowser/#/R-BTA-189488 UROS transforms HMB to URO3 IEA Bos taurus 57308 R-CFA-189425 https://reactome.org/PathwayBrowser/#/R-CFA-189425 UROD decarboxylates URO3 to COPRO3 IEA Canis familiaris 57308 R-CFA-189488 https://reactome.org/PathwayBrowser/#/R-CFA-189488 UROS transforms HMB to URO3 IEA Canis familiaris 57308 R-DDI-189425 https://reactome.org/PathwayBrowser/#/R-DDI-189425 UROD decarboxylates URO3 to COPRO3 IEA Dictyostelium discoideum 57308 R-DDI-189488 https://reactome.org/PathwayBrowser/#/R-DDI-189488 UROS transforms HMB to URO3 IEA Dictyostelium discoideum 57308 R-DME-189425 https://reactome.org/PathwayBrowser/#/R-DME-189425 UROD decarboxylates URO3 to COPRO3 IEA Drosophila melanogaster 57308 R-DME-189488 https://reactome.org/PathwayBrowser/#/R-DME-189488 UROS transforms HMB to URO3 IEA Drosophila melanogaster 57308 R-DRE-189425 https://reactome.org/PathwayBrowser/#/R-DRE-189425 UROD decarboxylates URO3 to COPRO3 IEA Danio rerio 57308 R-DRE-189488 https://reactome.org/PathwayBrowser/#/R-DRE-189488 UROS transforms HMB to URO3 IEA Danio rerio 57308 R-GGA-189425 https://reactome.org/PathwayBrowser/#/R-GGA-189425 UROD decarboxylates URO3 to COPRO3 IEA Gallus gallus 57308 R-GGA-189488 https://reactome.org/PathwayBrowser/#/R-GGA-189488 UROS transforms HMB to URO3 IEA Gallus gallus 57308 R-GGA-421482 https://reactome.org/PathwayBrowser/#/R-GGA-421482 hydroxymethylbilane => uroporphyrinogen III + H2O IEA Gallus gallus 57308 R-GGA-421515 https://reactome.org/PathwayBrowser/#/R-GGA-421515 uroporphyrinogen III => coproporphyrinogen III + 4 CO2 IEA Gallus gallus 57308 R-HSA-189425 https://reactome.org/PathwayBrowser/#/R-HSA-189425 UROD decarboxylates URO3 to COPRO3 TAS Homo sapiens 57308 R-HSA-189488 https://reactome.org/PathwayBrowser/#/R-HSA-189488 UROS transforms HMB to URO3 TAS Homo sapiens 57308 R-MMU-189425 https://reactome.org/PathwayBrowser/#/R-MMU-189425 UROD decarboxylates URO3 to COPRO3 IEA Mus musculus 57308 R-MMU-189488 https://reactome.org/PathwayBrowser/#/R-MMU-189488 UROS transforms HMB to URO3 IEA Mus musculus 57308 R-PFA-189425 https://reactome.org/PathwayBrowser/#/R-PFA-189425 UROD decarboxylates URO3 to COPRO3 IEA Plasmodium falciparum 57308 R-RNO-189425 https://reactome.org/PathwayBrowser/#/R-RNO-189425 UROD decarboxylates URO3 to COPRO3 IEA Rattus norvegicus 57308 R-RNO-189488 https://reactome.org/PathwayBrowser/#/R-RNO-189488 UROS transforms HMB to URO3 IEA Rattus norvegicus 57308 R-SCE-189425 https://reactome.org/PathwayBrowser/#/R-SCE-189425 UROD decarboxylates URO3 to COPRO3 IEA Saccharomyces cerevisiae 57308 R-SCE-189488 https://reactome.org/PathwayBrowser/#/R-SCE-189488 UROS transforms HMB to URO3 IEA Saccharomyces cerevisiae 57308 R-SPO-189425 https://reactome.org/PathwayBrowser/#/R-SPO-189425 UROD decarboxylates URO3 to COPRO3 IEA Schizosaccharomyces pombe 57308 R-SPO-189488 https://reactome.org/PathwayBrowser/#/R-SPO-189488 UROS transforms HMB to URO3 IEA Schizosaccharomyces pombe 57308 R-SSC-189425 https://reactome.org/PathwayBrowser/#/R-SSC-189425 UROD decarboxylates URO3 to COPRO3 IEA Sus scrofa 57308 R-SSC-189488 https://reactome.org/PathwayBrowser/#/R-SSC-189488 UROS transforms HMB to URO3 IEA Sus scrofa 57308 R-XTR-189425 https://reactome.org/PathwayBrowser/#/R-XTR-189425 UROD decarboxylates URO3 to COPRO3 IEA Xenopus tropicalis 57308 R-XTR-189488 https://reactome.org/PathwayBrowser/#/R-XTR-189488 UROS transforms HMB to URO3 IEA Xenopus tropicalis 57309 R-BTA-189421 https://reactome.org/PathwayBrowser/#/R-BTA-189421 CPO transforms COPRO3 to PPGEN9 IEA Bos taurus 57309 R-BTA-189425 https://reactome.org/PathwayBrowser/#/R-BTA-189425 UROD decarboxylates URO3 to COPRO3 IEA Bos taurus 57309 R-CFA-189421 https://reactome.org/PathwayBrowser/#/R-CFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Canis familiaris 57309 R-CFA-189425 https://reactome.org/PathwayBrowser/#/R-CFA-189425 UROD decarboxylates URO3 to COPRO3 IEA Canis familiaris 57309 R-DDI-189421 https://reactome.org/PathwayBrowser/#/R-DDI-189421 CPO transforms COPRO3 to PPGEN9 IEA Dictyostelium discoideum 57309 R-DDI-189425 https://reactome.org/PathwayBrowser/#/R-DDI-189425 UROD decarboxylates URO3 to COPRO3 IEA Dictyostelium discoideum 57309 R-DME-189421 https://reactome.org/PathwayBrowser/#/R-DME-189421 CPO transforms COPRO3 to PPGEN9 IEA Drosophila melanogaster 57309 R-DME-189425 https://reactome.org/PathwayBrowser/#/R-DME-189425 UROD decarboxylates URO3 to COPRO3 IEA Drosophila melanogaster 57309 R-DRE-189421 https://reactome.org/PathwayBrowser/#/R-DRE-189421 CPO transforms COPRO3 to PPGEN9 IEA Danio rerio 57309 R-DRE-189425 https://reactome.org/PathwayBrowser/#/R-DRE-189425 UROD decarboxylates URO3 to COPRO3 IEA Danio rerio 57309 R-GGA-189421 https://reactome.org/PathwayBrowser/#/R-GGA-189421 CPO transforms COPRO3 to PPGEN9 IEA Gallus gallus 57309 R-GGA-189425 https://reactome.org/PathwayBrowser/#/R-GGA-189425 UROD decarboxylates URO3 to COPRO3 IEA Gallus gallus 57309 R-GGA-421478 https://reactome.org/PathwayBrowser/#/R-GGA-421478 coproporphyrinogen III + 2 O2 => protoporphyrinogen IX + 2 H2O2 + 2 CO2 IEA Gallus gallus 57309 R-GGA-421485 https://reactome.org/PathwayBrowser/#/R-GGA-421485 Translocation of coproporphyrinogen III from the cytosol to the mitochondrial intermembrane space TAS Gallus gallus 57309 R-GGA-421515 https://reactome.org/PathwayBrowser/#/R-GGA-421515 uroporphyrinogen III => coproporphyrinogen III + 4 CO2 IEA Gallus gallus 57309 R-HSA-189421 https://reactome.org/PathwayBrowser/#/R-HSA-189421 CPO transforms COPRO3 to PPGEN9 TAS Homo sapiens 57309 R-HSA-189425 https://reactome.org/PathwayBrowser/#/R-HSA-189425 UROD decarboxylates URO3 to COPRO3 TAS Homo sapiens 57309 R-HSA-189467 https://reactome.org/PathwayBrowser/#/R-HSA-189467 Cytosolic COPRO3 translocates to mitochondrial intermembrane space TAS Homo sapiens 57309 R-MMU-189421 https://reactome.org/PathwayBrowser/#/R-MMU-189421 CPO transforms COPRO3 to PPGEN9 IEA Mus musculus 57309 R-MMU-189425 https://reactome.org/PathwayBrowser/#/R-MMU-189425 UROD decarboxylates URO3 to COPRO3 IEA Mus musculus 57309 R-PFA-189421 https://reactome.org/PathwayBrowser/#/R-PFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Plasmodium falciparum 57309 R-PFA-189425 https://reactome.org/PathwayBrowser/#/R-PFA-189425 UROD decarboxylates URO3 to COPRO3 IEA Plasmodium falciparum 57309 R-RNO-189421 https://reactome.org/PathwayBrowser/#/R-RNO-189421 CPO transforms COPRO3 to PPGEN9 IEA Rattus norvegicus 57309 R-RNO-189425 https://reactome.org/PathwayBrowser/#/R-RNO-189425 UROD decarboxylates URO3 to COPRO3 IEA Rattus norvegicus 57309 R-SCE-189421 https://reactome.org/PathwayBrowser/#/R-SCE-189421 CPO transforms COPRO3 to PPGEN9 IEA Saccharomyces cerevisiae 57309 R-SCE-189425 https://reactome.org/PathwayBrowser/#/R-SCE-189425 UROD decarboxylates URO3 to COPRO3 IEA Saccharomyces cerevisiae 57309 R-SPO-189421 https://reactome.org/PathwayBrowser/#/R-SPO-189421 CPO transforms COPRO3 to PPGEN9 IEA Schizosaccharomyces pombe 57309 R-SPO-189425 https://reactome.org/PathwayBrowser/#/R-SPO-189425 UROD decarboxylates URO3 to COPRO3 IEA Schizosaccharomyces pombe 57309 R-SSC-189421 https://reactome.org/PathwayBrowser/#/R-SSC-189421 CPO transforms COPRO3 to PPGEN9 IEA Sus scrofa 57309 R-SSC-189425 https://reactome.org/PathwayBrowser/#/R-SSC-189425 UROD decarboxylates URO3 to COPRO3 IEA Sus scrofa 57309 R-XTR-189421 https://reactome.org/PathwayBrowser/#/R-XTR-189421 CPO transforms COPRO3 to PPGEN9 IEA Xenopus tropicalis 57309 R-XTR-189425 https://reactome.org/PathwayBrowser/#/R-XTR-189425 UROD decarboxylates URO3 to COPRO3 IEA Xenopus tropicalis 57328 R-BTA-196754 https://reactome.org/PathwayBrowser/#/R-BTA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Bos taurus 57328 R-BTA-196773 https://reactome.org/PathwayBrowser/#/R-BTA-196773 COASY phosphorylates DP-CoA IEA Bos taurus 57328 R-BTA-9837337 https://reactome.org/PathwayBrowser/#/R-BTA-9837337 DCAKD phosphorylates DP-CoA IEA Bos taurus 57328 R-CEL-196754 https://reactome.org/PathwayBrowser/#/R-CEL-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Caenorhabditis elegans 57328 R-CEL-196773 https://reactome.org/PathwayBrowser/#/R-CEL-196773 COASY phosphorylates DP-CoA IEA Caenorhabditis elegans 57328 R-CEL-9837337 https://reactome.org/PathwayBrowser/#/R-CEL-9837337 DCAKD phosphorylates DP-CoA IEA Caenorhabditis elegans 57328 R-CFA-196754 https://reactome.org/PathwayBrowser/#/R-CFA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Canis familiaris 57328 R-CFA-196773 https://reactome.org/PathwayBrowser/#/R-CFA-196773 COASY phosphorylates DP-CoA IEA Canis familiaris 57328 R-CFA-9837337 https://reactome.org/PathwayBrowser/#/R-CFA-9837337 DCAKD phosphorylates DP-CoA IEA Canis familiaris 57328 R-DDI-196754 https://reactome.org/PathwayBrowser/#/R-DDI-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Dictyostelium discoideum 57328 R-DDI-196773 https://reactome.org/PathwayBrowser/#/R-DDI-196773 COASY phosphorylates DP-CoA IEA Dictyostelium discoideum 57328 R-DME-9837337 https://reactome.org/PathwayBrowser/#/R-DME-9837337 DCAKD phosphorylates DP-CoA IEA Drosophila melanogaster 57328 R-DRE-196754 https://reactome.org/PathwayBrowser/#/R-DRE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Danio rerio 57328 R-DRE-196773 https://reactome.org/PathwayBrowser/#/R-DRE-196773 COASY phosphorylates DP-CoA IEA Danio rerio 57328 R-DRE-9837337 https://reactome.org/PathwayBrowser/#/R-DRE-9837337 DCAKD phosphorylates DP-CoA IEA Danio rerio 57328 R-GGA-196754 https://reactome.org/PathwayBrowser/#/R-GGA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Gallus gallus 57328 R-GGA-196773 https://reactome.org/PathwayBrowser/#/R-GGA-196773 COASY phosphorylates DP-CoA IEA Gallus gallus 57328 R-GGA-9837337 https://reactome.org/PathwayBrowser/#/R-GGA-9837337 DCAKD phosphorylates DP-CoA IEA Gallus gallus 57328 R-HSA-196754 https://reactome.org/PathwayBrowser/#/R-HSA-196754 COASY transfers an adenylyl group from ATP to PPANT TAS Homo sapiens 57328 R-HSA-196773 https://reactome.org/PathwayBrowser/#/R-HSA-196773 COASY phosphorylates DP-CoA TAS Homo sapiens 57328 R-HSA-9837337 https://reactome.org/PathwayBrowser/#/R-HSA-9837337 DCAKD phosphorylates DP-CoA TAS Homo sapiens 57328 R-MMU-196754 https://reactome.org/PathwayBrowser/#/R-MMU-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Mus musculus 57328 R-MMU-196773 https://reactome.org/PathwayBrowser/#/R-MMU-196773 COASY phosphorylates DP-CoA IEA Mus musculus 57328 R-MMU-9837337 https://reactome.org/PathwayBrowser/#/R-MMU-9837337 DCAKD phosphorylates DP-CoA IEA Mus musculus 57328 R-PFA-9837337 https://reactome.org/PathwayBrowser/#/R-PFA-9837337 DCAKD phosphorylates DP-CoA IEA Plasmodium falciparum 57328 R-RNO-196754 https://reactome.org/PathwayBrowser/#/R-RNO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Rattus norvegicus 57328 R-RNO-196773 https://reactome.org/PathwayBrowser/#/R-RNO-196773 COASY phosphorylates DP-CoA IEA Rattus norvegicus 57328 R-RNO-9837337 https://reactome.org/PathwayBrowser/#/R-RNO-9837337 DCAKD phosphorylates DP-CoA IEA Rattus norvegicus 57328 R-SCE-196754 https://reactome.org/PathwayBrowser/#/R-SCE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Saccharomyces cerevisiae 57328 R-SCE-196773 https://reactome.org/PathwayBrowser/#/R-SCE-196773 COASY phosphorylates DP-CoA IEA Saccharomyces cerevisiae 57328 R-SCE-9837337 https://reactome.org/PathwayBrowser/#/R-SCE-9837337 DCAKD phosphorylates DP-CoA IEA Saccharomyces cerevisiae 57328 R-SPO-196754 https://reactome.org/PathwayBrowser/#/R-SPO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Schizosaccharomyces pombe 57328 R-SPO-196773 https://reactome.org/PathwayBrowser/#/R-SPO-196773 COASY phosphorylates DP-CoA IEA Schizosaccharomyces pombe 57328 R-SPO-9837337 https://reactome.org/PathwayBrowser/#/R-SPO-9837337 DCAKD phosphorylates DP-CoA IEA Schizosaccharomyces pombe 57328 R-SSC-196754 https://reactome.org/PathwayBrowser/#/R-SSC-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Sus scrofa 57328 R-SSC-196773 https://reactome.org/PathwayBrowser/#/R-SSC-196773 COASY phosphorylates DP-CoA IEA Sus scrofa 57328 R-SSC-9837337 https://reactome.org/PathwayBrowser/#/R-SSC-9837337 DCAKD phosphorylates DP-CoA IEA Sus scrofa 57328 R-XTR-196754 https://reactome.org/PathwayBrowser/#/R-XTR-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Xenopus tropicalis 57328 R-XTR-196773 https://reactome.org/PathwayBrowser/#/R-XTR-196773 COASY phosphorylates DP-CoA IEA Xenopus tropicalis 57328 R-XTR-9837337 https://reactome.org/PathwayBrowser/#/R-XTR-9837337 DCAKD phosphorylates DP-CoA IEA Xenopus tropicalis 57330 R-BTA-77256 https://reactome.org/PathwayBrowser/#/R-BTA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Bos taurus 57330 R-BTA-77263 https://reactome.org/PathwayBrowser/#/R-BTA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Bos taurus 57330 R-CEL-77256 https://reactome.org/PathwayBrowser/#/R-CEL-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Caenorhabditis elegans 57330 R-CFA-77256 https://reactome.org/PathwayBrowser/#/R-CFA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Canis familiaris 57330 R-CFA-77263 https://reactome.org/PathwayBrowser/#/R-CFA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Canis familiaris 57330 R-DDI-77256 https://reactome.org/PathwayBrowser/#/R-DDI-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Dictyostelium discoideum 57330 R-DME-77256 https://reactome.org/PathwayBrowser/#/R-DME-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Drosophila melanogaster 57330 R-DRE-77263 https://reactome.org/PathwayBrowser/#/R-DRE-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Danio rerio 57330 R-GGA-77263 https://reactome.org/PathwayBrowser/#/R-GGA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Gallus gallus 57330 R-HSA-77256 https://reactome.org/PathwayBrowser/#/R-HSA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA TAS Homo sapiens 57330 R-HSA-77263 https://reactome.org/PathwayBrowser/#/R-HSA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 TAS Homo sapiens 57330 R-MMU-77256 https://reactome.org/PathwayBrowser/#/R-MMU-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Mus musculus 57330 R-MMU-77263 https://reactome.org/PathwayBrowser/#/R-MMU-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Mus musculus 57330 R-RNO-77256 https://reactome.org/PathwayBrowser/#/R-RNO-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Rattus norvegicus 57330 R-RNO-77263 https://reactome.org/PathwayBrowser/#/R-RNO-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Rattus norvegicus 57330 R-SSC-77256 https://reactome.org/PathwayBrowser/#/R-SSC-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Sus scrofa 57330 R-SSC-77263 https://reactome.org/PathwayBrowser/#/R-SSC-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Sus scrofa 57330 R-XTR-77256 https://reactome.org/PathwayBrowser/#/R-XTR-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Xenopus tropicalis 57330 R-XTR-77263 https://reactome.org/PathwayBrowser/#/R-XTR-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Xenopus tropicalis 57332 R-BTA-71046 https://reactome.org/PathwayBrowser/#/R-BTA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Bos taurus 57332 R-BTA-77314 https://reactome.org/PathwayBrowser/#/R-BTA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Bos taurus 57332 R-BTA-77319 https://reactome.org/PathwayBrowser/#/R-BTA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Bos taurus 57332 R-CEL-71046 https://reactome.org/PathwayBrowser/#/R-CEL-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Caenorhabditis elegans 57332 R-CEL-77314 https://reactome.org/PathwayBrowser/#/R-CEL-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Caenorhabditis elegans 57332 R-CFA-71046 https://reactome.org/PathwayBrowser/#/R-CFA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Canis familiaris 57332 R-CFA-77314 https://reactome.org/PathwayBrowser/#/R-CFA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Canis familiaris 57332 R-CFA-77319 https://reactome.org/PathwayBrowser/#/R-CFA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Canis familiaris 57332 R-DDI-71046 https://reactome.org/PathwayBrowser/#/R-DDI-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Dictyostelium discoideum 57332 R-DDI-77314 https://reactome.org/PathwayBrowser/#/R-DDI-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Dictyostelium discoideum 57332 R-DME-71046 https://reactome.org/PathwayBrowser/#/R-DME-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Drosophila melanogaster 57332 R-DME-77314 https://reactome.org/PathwayBrowser/#/R-DME-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Drosophila melanogaster 57332 R-DME-77319 https://reactome.org/PathwayBrowser/#/R-DME-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Drosophila melanogaster 57332 R-DRE-71046 https://reactome.org/PathwayBrowser/#/R-DRE-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Danio rerio 57332 R-DRE-77319 https://reactome.org/PathwayBrowser/#/R-DRE-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Danio rerio 57332 R-GGA-71046 https://reactome.org/PathwayBrowser/#/R-GGA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Gallus gallus 57332 R-GGA-77319 https://reactome.org/PathwayBrowser/#/R-GGA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Gallus gallus 57332 R-HSA-71046 https://reactome.org/PathwayBrowser/#/R-HSA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 TAS Homo sapiens 57332 R-HSA-77314 https://reactome.org/PathwayBrowser/#/R-HSA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA TAS Homo sapiens 57332 R-HSA-77319 https://reactome.org/PathwayBrowser/#/R-HSA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 TAS Homo sapiens 57332 R-MMU-71046 https://reactome.org/PathwayBrowser/#/R-MMU-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Mus musculus 57332 R-MMU-77314 https://reactome.org/PathwayBrowser/#/R-MMU-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Mus musculus 57332 R-MMU-77319 https://reactome.org/PathwayBrowser/#/R-MMU-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Mus musculus 57332 R-RNO-71046 https://reactome.org/PathwayBrowser/#/R-RNO-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Rattus norvegicus 57332 R-RNO-77314 https://reactome.org/PathwayBrowser/#/R-RNO-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Rattus norvegicus 57332 R-RNO-77319 https://reactome.org/PathwayBrowser/#/R-RNO-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Rattus norvegicus 57332 R-SSC-71046 https://reactome.org/PathwayBrowser/#/R-SSC-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Sus scrofa 57332 R-SSC-77314 https://reactome.org/PathwayBrowser/#/R-SSC-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Sus scrofa 57332 R-SSC-77319 https://reactome.org/PathwayBrowser/#/R-SSC-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Sus scrofa 57332 R-XTR-71046 https://reactome.org/PathwayBrowser/#/R-XTR-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Xenopus tropicalis 57332 R-XTR-77314 https://reactome.org/PathwayBrowser/#/R-XTR-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Xenopus tropicalis 57332 R-XTR-77319 https://reactome.org/PathwayBrowser/#/R-XTR-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Xenopus tropicalis 57338 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 57338 R-BTA-70859 https://reactome.org/PathwayBrowser/#/R-BTA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Bos taurus 57338 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 57338 R-CEL-70859 https://reactome.org/PathwayBrowser/#/R-CEL-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Caenorhabditis elegans 57338 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 57338 R-CFA-70859 https://reactome.org/PathwayBrowser/#/R-CFA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Canis familiaris 57338 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 57338 R-DDI-70859 https://reactome.org/PathwayBrowser/#/R-DDI-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Dictyostelium discoideum 57338 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 57338 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 57338 R-DRE-70859 https://reactome.org/PathwayBrowser/#/R-DRE-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Danio rerio 57338 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 57338 R-GGA-70859 https://reactome.org/PathwayBrowser/#/R-GGA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Gallus gallus 57338 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 57338 R-HSA-70859 https://reactome.org/PathwayBrowser/#/R-HSA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 TAS Homo sapiens 57338 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 57338 R-MMU-70859 https://reactome.org/PathwayBrowser/#/R-MMU-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Mus musculus 57338 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 57338 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 57338 R-RNO-70859 https://reactome.org/PathwayBrowser/#/R-RNO-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Rattus norvegicus 57338 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 57338 R-SSC-70859 https://reactome.org/PathwayBrowser/#/R-SSC-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Sus scrofa 57338 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 57338 R-XTR-70859 https://reactome.org/PathwayBrowser/#/R-XTR-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Xenopus tropicalis 57344 R-BTA-508308 https://reactome.org/PathwayBrowser/#/R-BTA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Bos taurus 57344 R-BTA-70745 https://reactome.org/PathwayBrowser/#/R-BTA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Bos taurus 57344 R-BTA-70773 https://reactome.org/PathwayBrowser/#/R-BTA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Bos taurus 57344 R-CEL-508308 https://reactome.org/PathwayBrowser/#/R-CEL-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Caenorhabditis elegans 57344 R-CEL-70745 https://reactome.org/PathwayBrowser/#/R-CEL-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Caenorhabditis elegans 57344 R-CEL-70773 https://reactome.org/PathwayBrowser/#/R-CEL-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Caenorhabditis elegans 57344 R-CFA-508308 https://reactome.org/PathwayBrowser/#/R-CFA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Canis familiaris 57344 R-CFA-70745 https://reactome.org/PathwayBrowser/#/R-CFA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Canis familiaris 57344 R-CFA-70773 https://reactome.org/PathwayBrowser/#/R-CFA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Canis familiaris 57344 R-DDI-508308 https://reactome.org/PathwayBrowser/#/R-DDI-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Dictyostelium discoideum 57344 R-DDI-70745 https://reactome.org/PathwayBrowser/#/R-DDI-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Dictyostelium discoideum 57344 R-DDI-70773 https://reactome.org/PathwayBrowser/#/R-DDI-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Dictyostelium discoideum 57344 R-DME-508308 https://reactome.org/PathwayBrowser/#/R-DME-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Drosophila melanogaster 57344 R-DME-70745 https://reactome.org/PathwayBrowser/#/R-DME-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Drosophila melanogaster 57344 R-DME-70773 https://reactome.org/PathwayBrowser/#/R-DME-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Drosophila melanogaster 57344 R-DRE-70745 https://reactome.org/PathwayBrowser/#/R-DRE-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Danio rerio 57344 R-GGA-508308 https://reactome.org/PathwayBrowser/#/R-GGA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Gallus gallus 57344 R-GGA-70745 https://reactome.org/PathwayBrowser/#/R-GGA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Gallus gallus 57344 R-GGA-70773 https://reactome.org/PathwayBrowser/#/R-GGA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Gallus gallus 57344 R-HSA-508308 https://reactome.org/PathwayBrowser/#/R-HSA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] TAS Homo sapiens 57344 R-HSA-70745 https://reactome.org/PathwayBrowser/#/R-HSA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 TAS Homo sapiens 57344 R-HSA-70773 https://reactome.org/PathwayBrowser/#/R-HSA-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] TAS Homo sapiens 57344 R-MMU-508308 https://reactome.org/PathwayBrowser/#/R-MMU-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Mus musculus 57344 R-MMU-70745 https://reactome.org/PathwayBrowser/#/R-MMU-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Mus musculus 57344 R-MMU-70773 https://reactome.org/PathwayBrowser/#/R-MMU-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Mus musculus 57344 R-RNO-508308 https://reactome.org/PathwayBrowser/#/R-RNO-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Rattus norvegicus 57344 R-RNO-70745 https://reactome.org/PathwayBrowser/#/R-RNO-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Rattus norvegicus 57344 R-RNO-70773 https://reactome.org/PathwayBrowser/#/R-RNO-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Rattus norvegicus 57344 R-SSC-508308 https://reactome.org/PathwayBrowser/#/R-SSC-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Sus scrofa 57344 R-SSC-70745 https://reactome.org/PathwayBrowser/#/R-SSC-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Sus scrofa 57344 R-SSC-70773 https://reactome.org/PathwayBrowser/#/R-SSC-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Sus scrofa 57344 R-XTR-508308 https://reactome.org/PathwayBrowser/#/R-XTR-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] IEA Xenopus tropicalis 57344 R-XTR-70745 https://reactome.org/PathwayBrowser/#/R-XTR-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Xenopus tropicalis 57344 R-XTR-70773 https://reactome.org/PathwayBrowser/#/R-XTR-70773 beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] IEA Xenopus tropicalis 57345 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 57345 R-BTA-70745 https://reactome.org/PathwayBrowser/#/R-BTA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Bos taurus 57345 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 57345 R-CEL-70745 https://reactome.org/PathwayBrowser/#/R-CEL-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Caenorhabditis elegans 57345 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 57345 R-CFA-70745 https://reactome.org/PathwayBrowser/#/R-CFA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Canis familiaris 57345 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 57345 R-DDI-70745 https://reactome.org/PathwayBrowser/#/R-DDI-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Dictyostelium discoideum 57345 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 57345 R-DME-70745 https://reactome.org/PathwayBrowser/#/R-DME-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Drosophila melanogaster 57345 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 57345 R-DRE-70745 https://reactome.org/PathwayBrowser/#/R-DRE-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Danio rerio 57345 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 57345 R-GGA-70745 https://reactome.org/PathwayBrowser/#/R-GGA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Gallus gallus 57345 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 57345 R-HSA-70745 https://reactome.org/PathwayBrowser/#/R-HSA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 TAS Homo sapiens 57345 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 57345 R-MMU-70745 https://reactome.org/PathwayBrowser/#/R-MMU-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Mus musculus 57345 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 57345 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 57345 R-RNO-70745 https://reactome.org/PathwayBrowser/#/R-RNO-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Rattus norvegicus 57345 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 57345 R-SSC-70745 https://reactome.org/PathwayBrowser/#/R-SSC-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Sus scrofa 57345 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 57345 R-XTR-70745 https://reactome.org/PathwayBrowser/#/R-XTR-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Xenopus tropicalis 57368 R-BTA-2046083 https://reactome.org/PathwayBrowser/#/R-BTA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Bos taurus 57368 R-BTA-2046092 https://reactome.org/PathwayBrowser/#/R-BTA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Bos taurus 57368 R-BTA-548800 https://reactome.org/PathwayBrowser/#/R-BTA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Bos taurus 57368 R-BTA-548843 https://reactome.org/PathwayBrowser/#/R-BTA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Bos taurus 57368 R-BTA-8849345 https://reactome.org/PathwayBrowser/#/R-BTA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Bos taurus 57368 R-CEL-2046092 https://reactome.org/PathwayBrowser/#/R-CEL-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Caenorhabditis elegans 57368 R-CEL-548800 https://reactome.org/PathwayBrowser/#/R-CEL-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Caenorhabditis elegans 57368 R-CEL-548843 https://reactome.org/PathwayBrowser/#/R-CEL-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Caenorhabditis elegans 57368 R-CFA-2046083 https://reactome.org/PathwayBrowser/#/R-CFA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Canis familiaris 57368 R-CFA-2046092 https://reactome.org/PathwayBrowser/#/R-CFA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Canis familiaris 57368 R-CFA-548800 https://reactome.org/PathwayBrowser/#/R-CFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Canis familiaris 57368 R-CFA-548843 https://reactome.org/PathwayBrowser/#/R-CFA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Canis familiaris 57368 R-CFA-8849345 https://reactome.org/PathwayBrowser/#/R-CFA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Canis familiaris 57368 R-DDI-2046083 https://reactome.org/PathwayBrowser/#/R-DDI-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Dictyostelium discoideum 57368 R-DDI-548800 https://reactome.org/PathwayBrowser/#/R-DDI-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Dictyostelium discoideum 57368 R-DME-2046083 https://reactome.org/PathwayBrowser/#/R-DME-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Drosophila melanogaster 57368 R-DME-548800 https://reactome.org/PathwayBrowser/#/R-DME-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Drosophila melanogaster 57368 R-DME-548843 https://reactome.org/PathwayBrowser/#/R-DME-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Drosophila melanogaster 57368 R-DME-8849345 https://reactome.org/PathwayBrowser/#/R-DME-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Drosophila melanogaster 57368 R-DRE-2046083 https://reactome.org/PathwayBrowser/#/R-DRE-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Danio rerio 57368 R-DRE-548800 https://reactome.org/PathwayBrowser/#/R-DRE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Danio rerio 57368 R-DRE-548843 https://reactome.org/PathwayBrowser/#/R-DRE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Danio rerio 57368 R-DRE-8849345 https://reactome.org/PathwayBrowser/#/R-DRE-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Danio rerio 57368 R-GGA-2046083 https://reactome.org/PathwayBrowser/#/R-GGA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Gallus gallus 57368 R-GGA-2046092 https://reactome.org/PathwayBrowser/#/R-GGA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Gallus gallus 57368 R-GGA-548800 https://reactome.org/PathwayBrowser/#/R-GGA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Gallus gallus 57368 R-GGA-548843 https://reactome.org/PathwayBrowser/#/R-GGA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Gallus gallus 57368 R-GGA-8849345 https://reactome.org/PathwayBrowser/#/R-GGA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Gallus gallus 57368 R-HSA-2046083 https://reactome.org/PathwayBrowser/#/R-HSA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA TAS Homo sapiens 57368 R-HSA-2046092 https://reactome.org/PathwayBrowser/#/R-HSA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA TAS Homo sapiens 57368 R-HSA-548800 https://reactome.org/PathwayBrowser/#/R-HSA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA TAS Homo sapiens 57368 R-HSA-548843 https://reactome.org/PathwayBrowser/#/R-HSA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA TAS Homo sapiens 57368 R-HSA-8849345 https://reactome.org/PathwayBrowser/#/R-HSA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine TAS Homo sapiens 57368 R-MMU-2046083 https://reactome.org/PathwayBrowser/#/R-MMU-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Mus musculus 57368 R-MMU-2046092 https://reactome.org/PathwayBrowser/#/R-MMU-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Mus musculus 57368 R-MMU-548800 https://reactome.org/PathwayBrowser/#/R-MMU-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Mus musculus 57368 R-MMU-548843 https://reactome.org/PathwayBrowser/#/R-MMU-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Mus musculus 57368 R-MMU-8849345 https://reactome.org/PathwayBrowser/#/R-MMU-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Mus musculus 57368 R-PFA-548800 https://reactome.org/PathwayBrowser/#/R-PFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Plasmodium falciparum 57368 R-RNO-2046083 https://reactome.org/PathwayBrowser/#/R-RNO-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Rattus norvegicus 57368 R-RNO-2046092 https://reactome.org/PathwayBrowser/#/R-RNO-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Rattus norvegicus 57368 R-RNO-548800 https://reactome.org/PathwayBrowser/#/R-RNO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Rattus norvegicus 57368 R-RNO-548843 https://reactome.org/PathwayBrowser/#/R-RNO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Rattus norvegicus 57368 R-RNO-8849345 https://reactome.org/PathwayBrowser/#/R-RNO-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Rattus norvegicus 57368 R-SCE-548800 https://reactome.org/PathwayBrowser/#/R-SCE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Saccharomyces cerevisiae 57368 R-SCE-548843 https://reactome.org/PathwayBrowser/#/R-SCE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Saccharomyces cerevisiae 57368 R-SCE-8849345 https://reactome.org/PathwayBrowser/#/R-SCE-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Saccharomyces cerevisiae 57368 R-SPO-548800 https://reactome.org/PathwayBrowser/#/R-SPO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Schizosaccharomyces pombe 57368 R-SPO-548843 https://reactome.org/PathwayBrowser/#/R-SPO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Schizosaccharomyces pombe 57368 R-SSC-2046083 https://reactome.org/PathwayBrowser/#/R-SSC-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Sus scrofa 57368 R-SSC-2046092 https://reactome.org/PathwayBrowser/#/R-SSC-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Sus scrofa 57368 R-SSC-548800 https://reactome.org/PathwayBrowser/#/R-SSC-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Sus scrofa 57368 R-SSC-548843 https://reactome.org/PathwayBrowser/#/R-SSC-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Sus scrofa 57368 R-SSC-8849345 https://reactome.org/PathwayBrowser/#/R-SSC-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Sus scrofa 57368 R-XTR-2046083 https://reactome.org/PathwayBrowser/#/R-XTR-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Xenopus tropicalis 57368 R-XTR-2046092 https://reactome.org/PathwayBrowser/#/R-XTR-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Xenopus tropicalis 57368 R-XTR-548800 https://reactome.org/PathwayBrowser/#/R-XTR-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Xenopus tropicalis 57368 R-XTR-548843 https://reactome.org/PathwayBrowser/#/R-XTR-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Xenopus tropicalis 57368 R-XTR-8849345 https://reactome.org/PathwayBrowser/#/R-XTR-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Xenopus tropicalis 57369 R-BTA-159443 https://reactome.org/PathwayBrowser/#/R-BTA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Bos taurus 57369 R-BTA-159566 https://reactome.org/PathwayBrowser/#/R-BTA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Bos taurus 57369 R-CEL-159566 https://reactome.org/PathwayBrowser/#/R-CEL-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Caenorhabditis elegans 57369 R-CFA-159443 https://reactome.org/PathwayBrowser/#/R-CFA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 57369 R-CFA-159566 https://reactome.org/PathwayBrowser/#/R-CFA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Canis familiaris 57369 R-DRE-159443 https://reactome.org/PathwayBrowser/#/R-DRE-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Danio rerio 57369 R-GGA-159443 https://reactome.org/PathwayBrowser/#/R-GGA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 57369 R-GGA-159566 https://reactome.org/PathwayBrowser/#/R-GGA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Gallus gallus 57369 R-HSA-159443 https://reactome.org/PathwayBrowser/#/R-HSA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 57369 R-HSA-159566 https://reactome.org/PathwayBrowser/#/R-HSA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A TAS Homo sapiens 57369 R-MMU-159443 https://reactome.org/PathwayBrowser/#/R-MMU-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Mus musculus 57369 R-MMU-159566 https://reactome.org/PathwayBrowser/#/R-MMU-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Mus musculus 57369 R-RNO-159443 https://reactome.org/PathwayBrowser/#/R-RNO-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 57369 R-RNO-159566 https://reactome.org/PathwayBrowser/#/R-RNO-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Rattus norvegicus 57369 R-SSC-159443 https://reactome.org/PathwayBrowser/#/R-SSC-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 57369 R-SSC-159566 https://reactome.org/PathwayBrowser/#/R-SSC-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Sus scrofa 57369 R-XTR-159443 https://reactome.org/PathwayBrowser/#/R-XTR-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 57369 R-XTR-159566 https://reactome.org/PathwayBrowser/#/R-XTR-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Xenopus tropicalis 57371 R-BTA-77319 https://reactome.org/PathwayBrowser/#/R-BTA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Bos taurus 57371 R-BTA-77321 https://reactome.org/PathwayBrowser/#/R-BTA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Bos taurus 57371 R-CEL-77321 https://reactome.org/PathwayBrowser/#/R-CEL-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Caenorhabditis elegans 57371 R-CFA-77319 https://reactome.org/PathwayBrowser/#/R-CFA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Canis familiaris 57371 R-CFA-77321 https://reactome.org/PathwayBrowser/#/R-CFA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Canis familiaris 57371 R-DME-77319 https://reactome.org/PathwayBrowser/#/R-DME-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Drosophila melanogaster 57371 R-DME-77321 https://reactome.org/PathwayBrowser/#/R-DME-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Drosophila melanogaster 57371 R-DRE-77319 https://reactome.org/PathwayBrowser/#/R-DRE-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Danio rerio 57371 R-DRE-77321 https://reactome.org/PathwayBrowser/#/R-DRE-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Danio rerio 57371 R-GGA-77319 https://reactome.org/PathwayBrowser/#/R-GGA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Gallus gallus 57371 R-GGA-77321 https://reactome.org/PathwayBrowser/#/R-GGA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Gallus gallus 57371 R-HSA-77319 https://reactome.org/PathwayBrowser/#/R-HSA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 TAS Homo sapiens 57371 R-HSA-77321 https://reactome.org/PathwayBrowser/#/R-HSA-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA TAS Homo sapiens 57371 R-HSA-8875013 https://reactome.org/PathwayBrowser/#/R-HSA-8875013 ACSM3,ACSM6 ligate CoA to BUT IEA Homo sapiens 57371 R-MMU-77319 https://reactome.org/PathwayBrowser/#/R-MMU-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Mus musculus 57371 R-MMU-77321 https://reactome.org/PathwayBrowser/#/R-MMU-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Mus musculus 57371 R-MMU-8875039 https://reactome.org/PathwayBrowser/#/R-MMU-8875039 Acsm3 ligates CoA to BUT TAS Mus musculus 57371 R-RNO-77319 https://reactome.org/PathwayBrowser/#/R-RNO-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Rattus norvegicus 57371 R-RNO-77321 https://reactome.org/PathwayBrowser/#/R-RNO-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Rattus norvegicus 57371 R-SSC-77319 https://reactome.org/PathwayBrowser/#/R-SSC-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Sus scrofa 57371 R-SSC-77321 https://reactome.org/PathwayBrowser/#/R-SSC-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Sus scrofa 57371 R-XTR-77319 https://reactome.org/PathwayBrowser/#/R-XTR-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Xenopus tropicalis 57371 R-XTR-77321 https://reactome.org/PathwayBrowser/#/R-XTR-77321 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA IEA Xenopus tropicalis 57373 R-BTA-159425 https://reactome.org/PathwayBrowser/#/R-BTA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 57373 R-BTA-192341 https://reactome.org/PathwayBrowser/#/R-BTA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Bos taurus 57373 R-BTA-193385 https://reactome.org/PathwayBrowser/#/R-BTA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Bos taurus 57373 R-CEL-159425 https://reactome.org/PathwayBrowser/#/R-CEL-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 57373 R-CEL-159431 https://reactome.org/PathwayBrowser/#/R-CEL-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Caenorhabditis elegans 57373 R-CEL-192312 https://reactome.org/PathwayBrowser/#/R-CEL-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Caenorhabditis elegans 57373 R-CEL-193385 https://reactome.org/PathwayBrowser/#/R-CEL-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Caenorhabditis elegans 57373 R-CFA-159425 https://reactome.org/PathwayBrowser/#/R-CFA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 57373 R-CFA-159431 https://reactome.org/PathwayBrowser/#/R-CFA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Canis familiaris 57373 R-CFA-192312 https://reactome.org/PathwayBrowser/#/R-CFA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Canis familiaris 57373 R-CFA-192341 https://reactome.org/PathwayBrowser/#/R-CFA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Canis familiaris 57373 R-CFA-193385 https://reactome.org/PathwayBrowser/#/R-CFA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Canis familiaris 57373 R-DME-159425 https://reactome.org/PathwayBrowser/#/R-DME-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 57373 R-DME-192341 https://reactome.org/PathwayBrowser/#/R-DME-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Drosophila melanogaster 57373 R-DRE-159425 https://reactome.org/PathwayBrowser/#/R-DRE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 57373 R-DRE-192341 https://reactome.org/PathwayBrowser/#/R-DRE-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Danio rerio 57373 R-DRE-193385 https://reactome.org/PathwayBrowser/#/R-DRE-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Danio rerio 57373 R-GGA-159425 https://reactome.org/PathwayBrowser/#/R-GGA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 57373 R-GGA-159431 https://reactome.org/PathwayBrowser/#/R-GGA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Gallus gallus 57373 R-GGA-192312 https://reactome.org/PathwayBrowser/#/R-GGA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Gallus gallus 57373 R-GGA-192341 https://reactome.org/PathwayBrowser/#/R-GGA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Gallus gallus 57373 R-GGA-193385 https://reactome.org/PathwayBrowser/#/R-GGA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Gallus gallus 57373 R-HSA-159425 https://reactome.org/PathwayBrowser/#/R-HSA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 57373 R-HSA-159431 https://reactome.org/PathwayBrowser/#/R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine TAS Homo sapiens 57373 R-HSA-192312 https://reactome.org/PathwayBrowser/#/R-HSA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate TAS Homo sapiens 57373 R-HSA-192341 https://reactome.org/PathwayBrowser/#/R-HSA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA TAS Homo sapiens 57373 R-HSA-193385 https://reactome.org/PathwayBrowser/#/R-HSA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH TAS Homo sapiens 57373 R-MMU-159425 https://reactome.org/PathwayBrowser/#/R-MMU-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 57373 R-MMU-159431 https://reactome.org/PathwayBrowser/#/R-MMU-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Mus musculus 57373 R-MMU-192312 https://reactome.org/PathwayBrowser/#/R-MMU-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Mus musculus 57373 R-MMU-192341 https://reactome.org/PathwayBrowser/#/R-MMU-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Mus musculus 57373 R-MMU-193385 https://reactome.org/PathwayBrowser/#/R-MMU-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Mus musculus 57373 R-RNO-159425 https://reactome.org/PathwayBrowser/#/R-RNO-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 57373 R-RNO-159431 https://reactome.org/PathwayBrowser/#/R-RNO-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Rattus norvegicus 57373 R-RNO-192312 https://reactome.org/PathwayBrowser/#/R-RNO-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Rattus norvegicus 57373 R-RNO-192341 https://reactome.org/PathwayBrowser/#/R-RNO-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Rattus norvegicus 57373 R-RNO-193385 https://reactome.org/PathwayBrowser/#/R-RNO-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Rattus norvegicus 57373 R-SCE-159425 https://reactome.org/PathwayBrowser/#/R-SCE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 57373 R-SCE-193385 https://reactome.org/PathwayBrowser/#/R-SCE-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Saccharomyces cerevisiae 57373 R-SSC-159425 https://reactome.org/PathwayBrowser/#/R-SSC-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 57373 R-SSC-159431 https://reactome.org/PathwayBrowser/#/R-SSC-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Sus scrofa 57373 R-SSC-192312 https://reactome.org/PathwayBrowser/#/R-SSC-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Sus scrofa 57373 R-SSC-193385 https://reactome.org/PathwayBrowser/#/R-SSC-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Sus scrofa 57373 R-XTR-159425 https://reactome.org/PathwayBrowser/#/R-XTR-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 57373 R-XTR-159431 https://reactome.org/PathwayBrowser/#/R-XTR-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Xenopus tropicalis 57373 R-XTR-192312 https://reactome.org/PathwayBrowser/#/R-XTR-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Xenopus tropicalis 57373 R-XTR-193385 https://reactome.org/PathwayBrowser/#/R-XTR-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Xenopus tropicalis 57375 R-BTA-2534076 https://reactome.org/PathwayBrowser/#/R-BTA-2534076 Unknown Nat N-acylates Gly in Gnat1 TAS Bos taurus 57375 R-BTA-77263 https://reactome.org/PathwayBrowser/#/R-BTA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Bos taurus 57375 R-BTA-77271 https://reactome.org/PathwayBrowser/#/R-BTA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Bos taurus 57375 R-CEL-77271 https://reactome.org/PathwayBrowser/#/R-CEL-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Caenorhabditis elegans 57375 R-CFA-77263 https://reactome.org/PathwayBrowser/#/R-CFA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Canis familiaris 57375 R-CFA-77271 https://reactome.org/PathwayBrowser/#/R-CFA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Canis familiaris 57375 R-DME-77271 https://reactome.org/PathwayBrowser/#/R-DME-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Drosophila melanogaster 57375 R-DRE-77263 https://reactome.org/PathwayBrowser/#/R-DRE-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Danio rerio 57375 R-DRE-77271 https://reactome.org/PathwayBrowser/#/R-DRE-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Danio rerio 57375 R-GGA-77263 https://reactome.org/PathwayBrowser/#/R-GGA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Gallus gallus 57375 R-GGA-77271 https://reactome.org/PathwayBrowser/#/R-GGA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Gallus gallus 57375 R-HSA-2534040 https://reactome.org/PathwayBrowser/#/R-HSA-2534040 Unknown NAT N-acylates Gly in GNAT1 IEA Homo sapiens 57375 R-HSA-77263 https://reactome.org/PathwayBrowser/#/R-HSA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 TAS Homo sapiens 57375 R-HSA-77271 https://reactome.org/PathwayBrowser/#/R-HSA-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA TAS Homo sapiens 57375 R-MMU-77263 https://reactome.org/PathwayBrowser/#/R-MMU-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Mus musculus 57375 R-MMU-77271 https://reactome.org/PathwayBrowser/#/R-MMU-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Mus musculus 57375 R-RNO-77263 https://reactome.org/PathwayBrowser/#/R-RNO-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Rattus norvegicus 57375 R-RNO-77271 https://reactome.org/PathwayBrowser/#/R-RNO-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Rattus norvegicus 57375 R-SSC-77263 https://reactome.org/PathwayBrowser/#/R-SSC-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Sus scrofa 57375 R-SSC-77271 https://reactome.org/PathwayBrowser/#/R-SSC-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Sus scrofa 57375 R-XTR-77263 https://reactome.org/PathwayBrowser/#/R-XTR-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Xenopus tropicalis 57375 R-XTR-77271 https://reactome.org/PathwayBrowser/#/R-XTR-77271 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA IEA Xenopus tropicalis 57378 R-BTA-71037 https://reactome.org/PathwayBrowser/#/R-BTA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Bos taurus 57378 R-BTA-71046 https://reactome.org/PathwayBrowser/#/R-BTA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Bos taurus 57378 R-CEL-71037 https://reactome.org/PathwayBrowser/#/R-CEL-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 57378 R-CEL-71046 https://reactome.org/PathwayBrowser/#/R-CEL-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Caenorhabditis elegans 57378 R-CFA-71037 https://reactome.org/PathwayBrowser/#/R-CFA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Canis familiaris 57378 R-CFA-71046 https://reactome.org/PathwayBrowser/#/R-CFA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Canis familiaris 57378 R-DDI-71037 https://reactome.org/PathwayBrowser/#/R-DDI-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 57378 R-DDI-71046 https://reactome.org/PathwayBrowser/#/R-DDI-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Dictyostelium discoideum 57378 R-DME-71037 https://reactome.org/PathwayBrowser/#/R-DME-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 57378 R-DME-71046 https://reactome.org/PathwayBrowser/#/R-DME-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Drosophila melanogaster 57378 R-DRE-71037 https://reactome.org/PathwayBrowser/#/R-DRE-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Danio rerio 57378 R-DRE-71046 https://reactome.org/PathwayBrowser/#/R-DRE-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Danio rerio 57378 R-GGA-71037 https://reactome.org/PathwayBrowser/#/R-GGA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Gallus gallus 57378 R-GGA-71046 https://reactome.org/PathwayBrowser/#/R-GGA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Gallus gallus 57378 R-HSA-71037 https://reactome.org/PathwayBrowser/#/R-HSA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ TAS Homo sapiens 57378 R-HSA-71046 https://reactome.org/PathwayBrowser/#/R-HSA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 TAS Homo sapiens 57378 R-MMU-71037 https://reactome.org/PathwayBrowser/#/R-MMU-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Mus musculus 57378 R-MMU-71046 https://reactome.org/PathwayBrowser/#/R-MMU-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Mus musculus 57378 R-RNO-71037 https://reactome.org/PathwayBrowser/#/R-RNO-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 57378 R-RNO-71046 https://reactome.org/PathwayBrowser/#/R-RNO-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Rattus norvegicus 57378 R-SSC-71037 https://reactome.org/PathwayBrowser/#/R-SSC-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Sus scrofa 57378 R-SSC-71046 https://reactome.org/PathwayBrowser/#/R-SSC-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Sus scrofa 57378 R-XTR-71037 https://reactome.org/PathwayBrowser/#/R-XTR-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 57378 R-XTR-71046 https://reactome.org/PathwayBrowser/#/R-XTR-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Xenopus tropicalis 57379 R-BTA-200406 https://reactome.org/PathwayBrowser/#/R-BTA-200406 CPT1A,B transfers PALM to CAR IEA Bos taurus 57379 R-BTA-200410 https://reactome.org/PathwayBrowser/#/R-BTA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Bos taurus 57379 R-BTA-201035 https://reactome.org/PathwayBrowser/#/R-BTA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Bos taurus 57379 R-BTA-203567 https://reactome.org/PathwayBrowser/#/R-BTA-203567 palmitoylation of eNOS IEA Bos taurus 57379 R-BTA-2465919 https://reactome.org/PathwayBrowser/#/R-BTA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Bos taurus 57379 R-BTA-390425 https://reactome.org/PathwayBrowser/#/R-BTA-390425 FAR1 reduces PalmCoA to HXOL IEA Bos taurus 57379 R-BTA-390438 https://reactome.org/PathwayBrowser/#/R-BTA-390438 FAR2 reduces PalmCoA to HXOL IEA Bos taurus 57379 R-BTA-434382 https://reactome.org/PathwayBrowser/#/R-BTA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Bos taurus 57379 R-BTA-5358343 https://reactome.org/PathwayBrowser/#/R-BTA-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Bos taurus 57379 R-BTA-548814 https://reactome.org/PathwayBrowser/#/R-BTA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Bos taurus 57379 R-BTA-5682084 https://reactome.org/PathwayBrowser/#/R-BTA-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Bos taurus 57379 R-BTA-5686304 https://reactome.org/PathwayBrowser/#/R-BTA-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Bos taurus 57379 R-BTA-5690046 https://reactome.org/PathwayBrowser/#/R-BTA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Bos taurus 57379 R-BTA-75879 https://reactome.org/PathwayBrowser/#/R-BTA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Bos taurus 57379 R-BTA-77299 https://reactome.org/PathwayBrowser/#/R-BTA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Bos taurus 57379 R-BTA-8848582 https://reactome.org/PathwayBrowser/#/R-BTA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Bos taurus 57379 R-BTA-8848585 https://reactome.org/PathwayBrowser/#/R-BTA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Bos taurus 57379 R-BTA-9021072 https://reactome.org/PathwayBrowser/#/R-BTA-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Bos taurus 57379 R-BTA-9647982 https://reactome.org/PathwayBrowser/#/R-BTA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Bos taurus 57379 R-CEL-200406 https://reactome.org/PathwayBrowser/#/R-CEL-200406 CPT1A,B transfers PALM to CAR IEA Caenorhabditis elegans 57379 R-CEL-200410 https://reactome.org/PathwayBrowser/#/R-CEL-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Caenorhabditis elegans 57379 R-CEL-201035 https://reactome.org/PathwayBrowser/#/R-CEL-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Caenorhabditis elegans 57379 R-CEL-390425 https://reactome.org/PathwayBrowser/#/R-CEL-390425 FAR1 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 57379 R-CEL-390438 https://reactome.org/PathwayBrowser/#/R-CEL-390438 FAR2 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 57379 R-CEL-434382 https://reactome.org/PathwayBrowser/#/R-CEL-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Caenorhabditis elegans 57379 R-CEL-548814 https://reactome.org/PathwayBrowser/#/R-CEL-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Caenorhabditis elegans 57379 R-CEL-75879 https://reactome.org/PathwayBrowser/#/R-CEL-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Caenorhabditis elegans 57379 R-CEL-77299 https://reactome.org/PathwayBrowser/#/R-CEL-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 57379 R-CEL-8848582 https://reactome.org/PathwayBrowser/#/R-CEL-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Caenorhabditis elegans 57379 R-CEL-8848585 https://reactome.org/PathwayBrowser/#/R-CEL-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Caenorhabditis elegans 57379 R-CEL-9647982 https://reactome.org/PathwayBrowser/#/R-CEL-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Caenorhabditis elegans 57379 R-CFA-200406 https://reactome.org/PathwayBrowser/#/R-CFA-200406 CPT1A,B transfers PALM to CAR IEA Canis familiaris 57379 R-CFA-200410 https://reactome.org/PathwayBrowser/#/R-CFA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Canis familiaris 57379 R-CFA-201035 https://reactome.org/PathwayBrowser/#/R-CFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Canis familiaris 57379 R-CFA-2465919 https://reactome.org/PathwayBrowser/#/R-CFA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Canis familiaris 57379 R-CFA-390425 https://reactome.org/PathwayBrowser/#/R-CFA-390425 FAR1 reduces PalmCoA to HXOL IEA Canis familiaris 57379 R-CFA-390438 https://reactome.org/PathwayBrowser/#/R-CFA-390438 FAR2 reduces PalmCoA to HXOL IEA Canis familiaris 57379 R-CFA-434382 https://reactome.org/PathwayBrowser/#/R-CFA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Canis familiaris 57379 R-CFA-5358343 https://reactome.org/PathwayBrowser/#/R-CFA-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Canis familiaris 57379 R-CFA-548814 https://reactome.org/PathwayBrowser/#/R-CFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Canis familiaris 57379 R-CFA-5682084 https://reactome.org/PathwayBrowser/#/R-CFA-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Canis familiaris 57379 R-CFA-5686304 https://reactome.org/PathwayBrowser/#/R-CFA-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Canis familiaris 57379 R-CFA-5690046 https://reactome.org/PathwayBrowser/#/R-CFA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Canis familiaris 57379 R-CFA-75879 https://reactome.org/PathwayBrowser/#/R-CFA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Canis familiaris 57379 R-CFA-77299 https://reactome.org/PathwayBrowser/#/R-CFA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Canis familiaris 57379 R-CFA-8848582 https://reactome.org/PathwayBrowser/#/R-CFA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Canis familiaris 57379 R-CFA-8848585 https://reactome.org/PathwayBrowser/#/R-CFA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Canis familiaris 57379 R-CFA-9021072 https://reactome.org/PathwayBrowser/#/R-CFA-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Canis familiaris 57379 R-CFA-9647982 https://reactome.org/PathwayBrowser/#/R-CFA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Canis familiaris 57379 R-DDI-201035 https://reactome.org/PathwayBrowser/#/R-DDI-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Dictyostelium discoideum 57379 R-DDI-203567 https://reactome.org/PathwayBrowser/#/R-DDI-203567 palmitoylation of eNOS IEA Dictyostelium discoideum 57379 R-DDI-2465919 https://reactome.org/PathwayBrowser/#/R-DDI-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Dictyostelium discoideum 57379 R-DDI-390425 https://reactome.org/PathwayBrowser/#/R-DDI-390425 FAR1 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 57379 R-DDI-390438 https://reactome.org/PathwayBrowser/#/R-DDI-390438 FAR2 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 57379 R-DDI-548814 https://reactome.org/PathwayBrowser/#/R-DDI-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Dictyostelium discoideum 57379 R-DDI-5690046 https://reactome.org/PathwayBrowser/#/R-DDI-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Dictyostelium discoideum 57379 R-DDI-8848582 https://reactome.org/PathwayBrowser/#/R-DDI-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Dictyostelium discoideum 57379 R-DDI-8848585 https://reactome.org/PathwayBrowser/#/R-DDI-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Dictyostelium discoideum 57379 R-DME-200406 https://reactome.org/PathwayBrowser/#/R-DME-200406 CPT1A,B transfers PALM to CAR IEA Drosophila melanogaster 57379 R-DME-200410 https://reactome.org/PathwayBrowser/#/R-DME-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Drosophila melanogaster 57379 R-DME-201035 https://reactome.org/PathwayBrowser/#/R-DME-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Drosophila melanogaster 57379 R-DME-2465919 https://reactome.org/PathwayBrowser/#/R-DME-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Drosophila melanogaster 57379 R-DME-390425 https://reactome.org/PathwayBrowser/#/R-DME-390425 FAR1 reduces PalmCoA to HXOL IEA Drosophila melanogaster 57379 R-DME-390438 https://reactome.org/PathwayBrowser/#/R-DME-390438 FAR2 reduces PalmCoA to HXOL IEA Drosophila melanogaster 57379 R-DME-434382 https://reactome.org/PathwayBrowser/#/R-DME-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Drosophila melanogaster 57379 R-DME-5358343 https://reactome.org/PathwayBrowser/#/R-DME-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Drosophila melanogaster 57379 R-DME-548814 https://reactome.org/PathwayBrowser/#/R-DME-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Drosophila melanogaster 57379 R-DME-5682084 https://reactome.org/PathwayBrowser/#/R-DME-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Drosophila melanogaster 57379 R-DME-5690046 https://reactome.org/PathwayBrowser/#/R-DME-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Drosophila melanogaster 57379 R-DME-75879 https://reactome.org/PathwayBrowser/#/R-DME-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Drosophila melanogaster 57379 R-DME-77299 https://reactome.org/PathwayBrowser/#/R-DME-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 57379 R-DME-8848582 https://reactome.org/PathwayBrowser/#/R-DME-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Drosophila melanogaster 57379 R-DME-8848585 https://reactome.org/PathwayBrowser/#/R-DME-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Drosophila melanogaster 57379 R-DME-9021072 https://reactome.org/PathwayBrowser/#/R-DME-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Drosophila melanogaster 57379 R-DME-9647982 https://reactome.org/PathwayBrowser/#/R-DME-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Drosophila melanogaster 57379 R-DRE-200406 https://reactome.org/PathwayBrowser/#/R-DRE-200406 CPT1A,B transfers PALM to CAR IEA Danio rerio 57379 R-DRE-200410 https://reactome.org/PathwayBrowser/#/R-DRE-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Danio rerio 57379 R-DRE-201035 https://reactome.org/PathwayBrowser/#/R-DRE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Danio rerio 57379 R-DRE-2465919 https://reactome.org/PathwayBrowser/#/R-DRE-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Danio rerio 57379 R-DRE-390438 https://reactome.org/PathwayBrowser/#/R-DRE-390438 FAR2 reduces PalmCoA to HXOL IEA Danio rerio 57379 R-DRE-434382 https://reactome.org/PathwayBrowser/#/R-DRE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Danio rerio 57379 R-DRE-548814 https://reactome.org/PathwayBrowser/#/R-DRE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Danio rerio 57379 R-DRE-5682084 https://reactome.org/PathwayBrowser/#/R-DRE-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Danio rerio 57379 R-DRE-5686304 https://reactome.org/PathwayBrowser/#/R-DRE-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Danio rerio 57379 R-DRE-5690046 https://reactome.org/PathwayBrowser/#/R-DRE-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Danio rerio 57379 R-DRE-77299 https://reactome.org/PathwayBrowser/#/R-DRE-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Danio rerio 57379 R-DRE-8848582 https://reactome.org/PathwayBrowser/#/R-DRE-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Danio rerio 57379 R-DRE-8848585 https://reactome.org/PathwayBrowser/#/R-DRE-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Danio rerio 57379 R-DRE-9021072 https://reactome.org/PathwayBrowser/#/R-DRE-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Danio rerio 57379 R-GGA-200406 https://reactome.org/PathwayBrowser/#/R-GGA-200406 CPT1A,B transfers PALM to CAR IEA Gallus gallus 57379 R-GGA-200410 https://reactome.org/PathwayBrowser/#/R-GGA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Gallus gallus 57379 R-GGA-201035 https://reactome.org/PathwayBrowser/#/R-GGA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Gallus gallus 57379 R-GGA-203567 https://reactome.org/PathwayBrowser/#/R-GGA-203567 palmitoylation of eNOS IEA Gallus gallus 57379 R-GGA-2465919 https://reactome.org/PathwayBrowser/#/R-GGA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Gallus gallus 57379 R-GGA-390425 https://reactome.org/PathwayBrowser/#/R-GGA-390425 FAR1 reduces PalmCoA to HXOL IEA Gallus gallus 57379 R-GGA-390438 https://reactome.org/PathwayBrowser/#/R-GGA-390438 FAR2 reduces PalmCoA to HXOL IEA Gallus gallus 57379 R-GGA-433550 https://reactome.org/PathwayBrowser/#/R-GGA-433550 palmitoyl-CoA + serine => 3-dehydrosphinganine + CoASH + CO2 IEA Gallus gallus 57379 R-GGA-434382 https://reactome.org/PathwayBrowser/#/R-GGA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Gallus gallus 57379 R-GGA-5358343 https://reactome.org/PathwayBrowser/#/R-GGA-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Gallus gallus 57379 R-GGA-548814 https://reactome.org/PathwayBrowser/#/R-GGA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Gallus gallus 57379 R-GGA-5682084 https://reactome.org/PathwayBrowser/#/R-GGA-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Gallus gallus 57379 R-GGA-5686304 https://reactome.org/PathwayBrowser/#/R-GGA-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Gallus gallus 57379 R-GGA-8848582 https://reactome.org/PathwayBrowser/#/R-GGA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Gallus gallus 57379 R-GGA-8848585 https://reactome.org/PathwayBrowser/#/R-GGA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Gallus gallus 57379 R-GGA-9021072 https://reactome.org/PathwayBrowser/#/R-GGA-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Gallus gallus 57379 R-GGA-9647982 https://reactome.org/PathwayBrowser/#/R-GGA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Gallus gallus 57379 R-HSA-200406 https://reactome.org/PathwayBrowser/#/R-HSA-200406 CPT1A,B transfers PALM to CAR TAS Homo sapiens 57379 R-HSA-200410 https://reactome.org/PathwayBrowser/#/R-HSA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine TAS Homo sapiens 57379 R-HSA-201035 https://reactome.org/PathwayBrowser/#/R-HSA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA TAS Homo sapiens 57379 R-HSA-203567 https://reactome.org/PathwayBrowser/#/R-HSA-203567 palmitoylation of eNOS TAS Homo sapiens 57379 R-HSA-2465919 https://reactome.org/PathwayBrowser/#/R-HSA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM TAS Homo sapiens 57379 R-HSA-390425 https://reactome.org/PathwayBrowser/#/R-HSA-390425 FAR1 reduces PalmCoA to HXOL TAS Homo sapiens 57379 R-HSA-390438 https://reactome.org/PathwayBrowser/#/R-HSA-390438 FAR2 reduces PalmCoA to HXOL TAS Homo sapiens 57379 R-HSA-434382 https://reactome.org/PathwayBrowser/#/R-HSA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell TAS Homo sapiens 57379 R-HSA-5358343 https://reactome.org/PathwayBrowser/#/R-HSA-5358343 HHAT palmitoylates Hh N-terminal fragment TAS Homo sapiens 57379 R-HSA-548814 https://reactome.org/PathwayBrowser/#/R-HSA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA TAS Homo sapiens 57379 R-HSA-5682084 https://reactome.org/PathwayBrowser/#/R-HSA-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer TAS Homo sapiens 57379 R-HSA-5686304 https://reactome.org/PathwayBrowser/#/R-HSA-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 TAS Homo sapiens 57379 R-HSA-5690046 https://reactome.org/PathwayBrowser/#/R-HSA-5690046 PPT2 hydrolyses PALMCoA to PALM TAS Homo sapiens 57379 R-HSA-75879 https://reactome.org/PathwayBrowser/#/R-HSA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH TAS Homo sapiens 57379 R-HSA-77299 https://reactome.org/PathwayBrowser/#/R-HSA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 TAS Homo sapiens 57379 R-HSA-8848582 https://reactome.org/PathwayBrowser/#/R-HSA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester TAS Homo sapiens 57379 R-HSA-8848585 https://reactome.org/PathwayBrowser/#/R-HSA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM TAS Homo sapiens 57379 R-HSA-9021072 https://reactome.org/PathwayBrowser/#/R-HSA-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 TAS Homo sapiens 57379 R-HSA-9647982 https://reactome.org/PathwayBrowser/#/R-HSA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated TAS Homo sapiens 57379 R-HSA-9683653 https://reactome.org/PathwayBrowser/#/R-HSA-9683653 Spike protein gets palmitoylated TAS Homo sapiens 57379 R-HSA-9683720 https://reactome.org/PathwayBrowser/#/R-HSA-9683720 E protein gets palmitoylated TAS Homo sapiens 57379 R-HSA-9694341 https://reactome.org/PathwayBrowser/#/R-HSA-9694341 Spike protein gets palmitoylated TAS Homo sapiens 57379 R-HSA-9694401 https://reactome.org/PathwayBrowser/#/R-HSA-9694401 E protein gets palmitoylated IEA Homo sapiens 57379 R-HSA-9829047 https://reactome.org/PathwayBrowser/#/R-HSA-9829047 F0 is palmitoylated TAS Homo sapiens 57379 R-HSA-9830875 https://reactome.org/PathwayBrowser/#/R-HSA-9830875 G is palmitoylated TAS Homo sapiens 57379 R-MMU-200406 https://reactome.org/PathwayBrowser/#/R-MMU-200406 CPT1A,B transfers PALM to CAR IEA Mus musculus 57379 R-MMU-200410 https://reactome.org/PathwayBrowser/#/R-MMU-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Mus musculus 57379 R-MMU-201035 https://reactome.org/PathwayBrowser/#/R-MMU-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Mus musculus 57379 R-MMU-203567 https://reactome.org/PathwayBrowser/#/R-MMU-203567 palmitoylation of eNOS IEA Mus musculus 57379 R-MMU-2465919 https://reactome.org/PathwayBrowser/#/R-MMU-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Mus musculus 57379 R-MMU-390425 https://reactome.org/PathwayBrowser/#/R-MMU-390425 FAR1 reduces PalmCoA to HXOL IEA Mus musculus 57379 R-MMU-390438 https://reactome.org/PathwayBrowser/#/R-MMU-390438 FAR2 reduces PalmCoA to HXOL IEA Mus musculus 57379 R-MMU-434382 https://reactome.org/PathwayBrowser/#/R-MMU-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Mus musculus 57379 R-MMU-5358343 https://reactome.org/PathwayBrowser/#/R-MMU-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Mus musculus 57379 R-MMU-548814 https://reactome.org/PathwayBrowser/#/R-MMU-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Mus musculus 57379 R-MMU-5682084 https://reactome.org/PathwayBrowser/#/R-MMU-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Mus musculus 57379 R-MMU-5686304 https://reactome.org/PathwayBrowser/#/R-MMU-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Mus musculus 57379 R-MMU-5690046 https://reactome.org/PathwayBrowser/#/R-MMU-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Mus musculus 57379 R-MMU-75879 https://reactome.org/PathwayBrowser/#/R-MMU-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Mus musculus 57379 R-MMU-77299 https://reactome.org/PathwayBrowser/#/R-MMU-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Mus musculus 57379 R-MMU-8848582 https://reactome.org/PathwayBrowser/#/R-MMU-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Mus musculus 57379 R-MMU-8848585 https://reactome.org/PathwayBrowser/#/R-MMU-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Mus musculus 57379 R-MMU-9021072 https://reactome.org/PathwayBrowser/#/R-MMU-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Mus musculus 57379 R-MMU-9647982 https://reactome.org/PathwayBrowser/#/R-MMU-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Mus musculus 57379 R-PFA-201035 https://reactome.org/PathwayBrowser/#/R-PFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Plasmodium falciparum 57379 R-PFA-548814 https://reactome.org/PathwayBrowser/#/R-PFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Plasmodium falciparum 57379 R-RNO-200406 https://reactome.org/PathwayBrowser/#/R-RNO-200406 CPT1A,B transfers PALM to CAR IEA Rattus norvegicus 57379 R-RNO-200410 https://reactome.org/PathwayBrowser/#/R-RNO-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Rattus norvegicus 57379 R-RNO-201035 https://reactome.org/PathwayBrowser/#/R-RNO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Rattus norvegicus 57379 R-RNO-203567 https://reactome.org/PathwayBrowser/#/R-RNO-203567 palmitoylation of eNOS IEA Rattus norvegicus 57379 R-RNO-2465919 https://reactome.org/PathwayBrowser/#/R-RNO-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Rattus norvegicus 57379 R-RNO-390425 https://reactome.org/PathwayBrowser/#/R-RNO-390425 FAR1 reduces PalmCoA to HXOL IEA Rattus norvegicus 57379 R-RNO-390438 https://reactome.org/PathwayBrowser/#/R-RNO-390438 FAR2 reduces PalmCoA to HXOL IEA Rattus norvegicus 57379 R-RNO-434382 https://reactome.org/PathwayBrowser/#/R-RNO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Rattus norvegicus 57379 R-RNO-5358343 https://reactome.org/PathwayBrowser/#/R-RNO-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Rattus norvegicus 57379 R-RNO-548814 https://reactome.org/PathwayBrowser/#/R-RNO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Rattus norvegicus 57379 R-RNO-5682084 https://reactome.org/PathwayBrowser/#/R-RNO-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Rattus norvegicus 57379 R-RNO-5686304 https://reactome.org/PathwayBrowser/#/R-RNO-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Rattus norvegicus 57379 R-RNO-5690046 https://reactome.org/PathwayBrowser/#/R-RNO-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Rattus norvegicus 57379 R-RNO-75879 https://reactome.org/PathwayBrowser/#/R-RNO-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Rattus norvegicus 57379 R-RNO-77299 https://reactome.org/PathwayBrowser/#/R-RNO-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 57379 R-RNO-8848582 https://reactome.org/PathwayBrowser/#/R-RNO-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Rattus norvegicus 57379 R-RNO-8848585 https://reactome.org/PathwayBrowser/#/R-RNO-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Rattus norvegicus 57379 R-RNO-9021072 https://reactome.org/PathwayBrowser/#/R-RNO-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Rattus norvegicus 57379 R-RNO-9647982 https://reactome.org/PathwayBrowser/#/R-RNO-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Rattus norvegicus 57379 R-SCE-201035 https://reactome.org/PathwayBrowser/#/R-SCE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Saccharomyces cerevisiae 57379 R-SCE-434382 https://reactome.org/PathwayBrowser/#/R-SCE-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Saccharomyces cerevisiae 57379 R-SCE-548814 https://reactome.org/PathwayBrowser/#/R-SCE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Saccharomyces cerevisiae 57379 R-SCE-8848582 https://reactome.org/PathwayBrowser/#/R-SCE-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Saccharomyces cerevisiae 57379 R-SCE-8848585 https://reactome.org/PathwayBrowser/#/R-SCE-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Saccharomyces cerevisiae 57379 R-SPO-201035 https://reactome.org/PathwayBrowser/#/R-SPO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Schizosaccharomyces pombe 57379 R-SPO-434382 https://reactome.org/PathwayBrowser/#/R-SPO-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Schizosaccharomyces pombe 57379 R-SPO-548814 https://reactome.org/PathwayBrowser/#/R-SPO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Schizosaccharomyces pombe 57379 R-SPO-8848582 https://reactome.org/PathwayBrowser/#/R-SPO-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Schizosaccharomyces pombe 57379 R-SPO-8848585 https://reactome.org/PathwayBrowser/#/R-SPO-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Schizosaccharomyces pombe 57379 R-SSC-200406 https://reactome.org/PathwayBrowser/#/R-SSC-200406 CPT1A,B transfers PALM to CAR IEA Sus scrofa 57379 R-SSC-200410 https://reactome.org/PathwayBrowser/#/R-SSC-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Sus scrofa 57379 R-SSC-201035 https://reactome.org/PathwayBrowser/#/R-SSC-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Sus scrofa 57379 R-SSC-203567 https://reactome.org/PathwayBrowser/#/R-SSC-203567 palmitoylation of eNOS IEA Sus scrofa 57379 R-SSC-2465919 https://reactome.org/PathwayBrowser/#/R-SSC-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Sus scrofa 57379 R-SSC-390425 https://reactome.org/PathwayBrowser/#/R-SSC-390425 FAR1 reduces PalmCoA to HXOL IEA Sus scrofa 57379 R-SSC-390438 https://reactome.org/PathwayBrowser/#/R-SSC-390438 FAR2 reduces PalmCoA to HXOL IEA Sus scrofa 57379 R-SSC-434382 https://reactome.org/PathwayBrowser/#/R-SSC-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Sus scrofa 57379 R-SSC-5358343 https://reactome.org/PathwayBrowser/#/R-SSC-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Sus scrofa 57379 R-SSC-548814 https://reactome.org/PathwayBrowser/#/R-SSC-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Sus scrofa 57379 R-SSC-5682084 https://reactome.org/PathwayBrowser/#/R-SSC-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Sus scrofa 57379 R-SSC-5686304 https://reactome.org/PathwayBrowser/#/R-SSC-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Sus scrofa 57379 R-SSC-5690046 https://reactome.org/PathwayBrowser/#/R-SSC-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Sus scrofa 57379 R-SSC-75879 https://reactome.org/PathwayBrowser/#/R-SSC-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Sus scrofa 57379 R-SSC-77299 https://reactome.org/PathwayBrowser/#/R-SSC-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Sus scrofa 57379 R-SSC-8848582 https://reactome.org/PathwayBrowser/#/R-SSC-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Sus scrofa 57379 R-SSC-8848585 https://reactome.org/PathwayBrowser/#/R-SSC-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Sus scrofa 57379 R-SSC-9021072 https://reactome.org/PathwayBrowser/#/R-SSC-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Sus scrofa 57379 R-SSC-9647982 https://reactome.org/PathwayBrowser/#/R-SSC-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Sus scrofa 57379 R-XTR-200406 https://reactome.org/PathwayBrowser/#/R-XTR-200406 CPT1A,B transfers PALM to CAR IEA Xenopus tropicalis 57379 R-XTR-200410 https://reactome.org/PathwayBrowser/#/R-XTR-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine IEA Xenopus tropicalis 57379 R-XTR-201035 https://reactome.org/PathwayBrowser/#/R-XTR-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Xenopus tropicalis 57379 R-XTR-2465919 https://reactome.org/PathwayBrowser/#/R-XTR-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Xenopus tropicalis 57379 R-XTR-434382 https://reactome.org/PathwayBrowser/#/R-XTR-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Xenopus tropicalis 57379 R-XTR-5358343 https://reactome.org/PathwayBrowser/#/R-XTR-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Xenopus tropicalis 57379 R-XTR-548814 https://reactome.org/PathwayBrowser/#/R-XTR-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Xenopus tropicalis 57379 R-XTR-5682084 https://reactome.org/PathwayBrowser/#/R-XTR-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer IEA Xenopus tropicalis 57379 R-XTR-5686304 https://reactome.org/PathwayBrowser/#/R-XTR-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 IEA Xenopus tropicalis 57379 R-XTR-5690046 https://reactome.org/PathwayBrowser/#/R-XTR-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Xenopus tropicalis 57379 R-XTR-75879 https://reactome.org/PathwayBrowser/#/R-XTR-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Xenopus tropicalis 57379 R-XTR-8848582 https://reactome.org/PathwayBrowser/#/R-XTR-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Xenopus tropicalis 57379 R-XTR-8848585 https://reactome.org/PathwayBrowser/#/R-XTR-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Xenopus tropicalis 57379 R-XTR-9021072 https://reactome.org/PathwayBrowser/#/R-XTR-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Xenopus tropicalis 57380 R-BTA-548815 https://reactome.org/PathwayBrowser/#/R-BTA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Bos taurus 57380 R-CFA-548815 https://reactome.org/PathwayBrowser/#/R-CFA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Canis familiaris 57380 R-DME-548815 https://reactome.org/PathwayBrowser/#/R-DME-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Drosophila melanogaster 57380 R-DRE-548815 https://reactome.org/PathwayBrowser/#/R-DRE-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Danio rerio 57380 R-GGA-548815 https://reactome.org/PathwayBrowser/#/R-GGA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Gallus gallus 57380 R-HSA-548815 https://reactome.org/PathwayBrowser/#/R-HSA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA TAS Homo sapiens 57380 R-MMU-548815 https://reactome.org/PathwayBrowser/#/R-MMU-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Mus musculus 57380 R-RNO-548815 https://reactome.org/PathwayBrowser/#/R-RNO-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Rattus norvegicus 57380 R-SSC-548815 https://reactome.org/PathwayBrowser/#/R-SSC-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Sus scrofa 57380 R-XTR-548815 https://reactome.org/PathwayBrowser/#/R-XTR-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Xenopus tropicalis 57384 R-BTA-200406 https://reactome.org/PathwayBrowser/#/R-BTA-200406 CPT1A,B transfers PALM to CAR IEA Bos taurus 57384 R-BTA-200555 https://reactome.org/PathwayBrowser/#/R-BTA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Bos taurus 57384 R-BTA-2046083 https://reactome.org/PathwayBrowser/#/R-BTA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Bos taurus 57384 R-BTA-2046088 https://reactome.org/PathwayBrowser/#/R-BTA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Bos taurus 57384 R-BTA-2046090 https://reactome.org/PathwayBrowser/#/R-BTA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 57384 R-BTA-2046094 https://reactome.org/PathwayBrowser/#/R-BTA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Bos taurus 57384 R-BTA-2046095 https://reactome.org/PathwayBrowser/#/R-BTA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Bos taurus 57384 R-BTA-2046100 https://reactome.org/PathwayBrowser/#/R-BTA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Bos taurus 57384 R-BTA-548800 https://reactome.org/PathwayBrowser/#/R-BTA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Bos taurus 57384 R-BTA-548814 https://reactome.org/PathwayBrowser/#/R-BTA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Bos taurus 57384 R-BTA-548815 https://reactome.org/PathwayBrowser/#/R-BTA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Bos taurus 57384 R-BTA-75851 https://reactome.org/PathwayBrowser/#/R-BTA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 57384 R-BTA-75872 https://reactome.org/PathwayBrowser/#/R-BTA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Bos taurus 57384 R-BTA-8876889 https://reactome.org/PathwayBrowser/#/R-BTA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 57384 R-BTA-8933547 https://reactome.org/PathwayBrowser/#/R-BTA-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Bos taurus 57384 R-BTA-977317 https://reactome.org/PathwayBrowser/#/R-BTA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Bos taurus 57384 R-CEL-200406 https://reactome.org/PathwayBrowser/#/R-CEL-200406 CPT1A,B transfers PALM to CAR IEA Caenorhabditis elegans 57384 R-CEL-200555 https://reactome.org/PathwayBrowser/#/R-CEL-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Caenorhabditis elegans 57384 R-CEL-2046088 https://reactome.org/PathwayBrowser/#/R-CEL-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Caenorhabditis elegans 57384 R-CEL-2046094 https://reactome.org/PathwayBrowser/#/R-CEL-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Caenorhabditis elegans 57384 R-CEL-548800 https://reactome.org/PathwayBrowser/#/R-CEL-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Caenorhabditis elegans 57384 R-CEL-548814 https://reactome.org/PathwayBrowser/#/R-CEL-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Caenorhabditis elegans 57384 R-CEL-75851 https://reactome.org/PathwayBrowser/#/R-CEL-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 57384 R-CEL-75872 https://reactome.org/PathwayBrowser/#/R-CEL-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Caenorhabditis elegans 57384 R-CEL-8876889 https://reactome.org/PathwayBrowser/#/R-CEL-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 57384 R-CEL-977317 https://reactome.org/PathwayBrowser/#/R-CEL-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Caenorhabditis elegans 57384 R-CFA-200406 https://reactome.org/PathwayBrowser/#/R-CFA-200406 CPT1A,B transfers PALM to CAR IEA Canis familiaris 57384 R-CFA-200555 https://reactome.org/PathwayBrowser/#/R-CFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Canis familiaris 57384 R-CFA-2046083 https://reactome.org/PathwayBrowser/#/R-CFA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Canis familiaris 57384 R-CFA-2046088 https://reactome.org/PathwayBrowser/#/R-CFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Canis familiaris 57384 R-CFA-2046090 https://reactome.org/PathwayBrowser/#/R-CFA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 57384 R-CFA-2046094 https://reactome.org/PathwayBrowser/#/R-CFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Canis familiaris 57384 R-CFA-2046095 https://reactome.org/PathwayBrowser/#/R-CFA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Canis familiaris 57384 R-CFA-2046100 https://reactome.org/PathwayBrowser/#/R-CFA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Canis familiaris 57384 R-CFA-548800 https://reactome.org/PathwayBrowser/#/R-CFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Canis familiaris 57384 R-CFA-548814 https://reactome.org/PathwayBrowser/#/R-CFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Canis familiaris 57384 R-CFA-548815 https://reactome.org/PathwayBrowser/#/R-CFA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Canis familiaris 57384 R-CFA-75851 https://reactome.org/PathwayBrowser/#/R-CFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 57384 R-CFA-75872 https://reactome.org/PathwayBrowser/#/R-CFA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Canis familiaris 57384 R-CFA-8876889 https://reactome.org/PathwayBrowser/#/R-CFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 57384 R-CFA-8933547 https://reactome.org/PathwayBrowser/#/R-CFA-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Canis familiaris 57384 R-CFA-977317 https://reactome.org/PathwayBrowser/#/R-CFA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Canis familiaris 57384 R-DDI-200555 https://reactome.org/PathwayBrowser/#/R-DDI-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Dictyostelium discoideum 57384 R-DDI-2046083 https://reactome.org/PathwayBrowser/#/R-DDI-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Dictyostelium discoideum 57384 R-DDI-2046088 https://reactome.org/PathwayBrowser/#/R-DDI-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Dictyostelium discoideum 57384 R-DDI-2046090 https://reactome.org/PathwayBrowser/#/R-DDI-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Dictyostelium discoideum 57384 R-DDI-2046094 https://reactome.org/PathwayBrowser/#/R-DDI-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Dictyostelium discoideum 57384 R-DDI-2046095 https://reactome.org/PathwayBrowser/#/R-DDI-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Dictyostelium discoideum 57384 R-DDI-2046100 https://reactome.org/PathwayBrowser/#/R-DDI-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Dictyostelium discoideum 57384 R-DDI-548800 https://reactome.org/PathwayBrowser/#/R-DDI-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Dictyostelium discoideum 57384 R-DDI-548814 https://reactome.org/PathwayBrowser/#/R-DDI-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Dictyostelium discoideum 57384 R-DDI-75851 https://reactome.org/PathwayBrowser/#/R-DDI-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 57384 R-DDI-75872 https://reactome.org/PathwayBrowser/#/R-DDI-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Dictyostelium discoideum 57384 R-DDI-8876889 https://reactome.org/PathwayBrowser/#/R-DDI-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 57384 R-DDI-8933547 https://reactome.org/PathwayBrowser/#/R-DDI-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Dictyostelium discoideum 57384 R-DDI-977317 https://reactome.org/PathwayBrowser/#/R-DDI-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Dictyostelium discoideum 57384 R-DME-200406 https://reactome.org/PathwayBrowser/#/R-DME-200406 CPT1A,B transfers PALM to CAR IEA Drosophila melanogaster 57384 R-DME-200555 https://reactome.org/PathwayBrowser/#/R-DME-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Drosophila melanogaster 57384 R-DME-2046083 https://reactome.org/PathwayBrowser/#/R-DME-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Drosophila melanogaster 57384 R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster 57384 R-DME-2046090 https://reactome.org/PathwayBrowser/#/R-DME-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Drosophila melanogaster 57384 R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster 57384 R-DME-2046095 https://reactome.org/PathwayBrowser/#/R-DME-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Drosophila melanogaster 57384 R-DME-2046100 https://reactome.org/PathwayBrowser/#/R-DME-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Drosophila melanogaster 57384 R-DME-548800 https://reactome.org/PathwayBrowser/#/R-DME-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Drosophila melanogaster 57384 R-DME-548814 https://reactome.org/PathwayBrowser/#/R-DME-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Drosophila melanogaster 57384 R-DME-548815 https://reactome.org/PathwayBrowser/#/R-DME-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Drosophila melanogaster 57384 R-DME-75851 https://reactome.org/PathwayBrowser/#/R-DME-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 57384 R-DME-75872 https://reactome.org/PathwayBrowser/#/R-DME-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Drosophila melanogaster 57384 R-DME-8876889 https://reactome.org/PathwayBrowser/#/R-DME-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 57384 R-DME-8933547 https://reactome.org/PathwayBrowser/#/R-DME-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Drosophila melanogaster 57384 R-DRE-200406 https://reactome.org/PathwayBrowser/#/R-DRE-200406 CPT1A,B transfers PALM to CAR IEA Danio rerio 57384 R-DRE-2046083 https://reactome.org/PathwayBrowser/#/R-DRE-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Danio rerio 57384 R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio 57384 R-DRE-2046090 https://reactome.org/PathwayBrowser/#/R-DRE-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 57384 R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio 57384 R-DRE-2046095 https://reactome.org/PathwayBrowser/#/R-DRE-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Danio rerio 57384 R-DRE-2046100 https://reactome.org/PathwayBrowser/#/R-DRE-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Danio rerio 57384 R-DRE-548800 https://reactome.org/PathwayBrowser/#/R-DRE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Danio rerio 57384 R-DRE-548814 https://reactome.org/PathwayBrowser/#/R-DRE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Danio rerio 57384 R-DRE-548815 https://reactome.org/PathwayBrowser/#/R-DRE-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Danio rerio 57384 R-DRE-75872 https://reactome.org/PathwayBrowser/#/R-DRE-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Danio rerio 57384 R-DRE-977317 https://reactome.org/PathwayBrowser/#/R-DRE-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Danio rerio 57384 R-GGA-200406 https://reactome.org/PathwayBrowser/#/R-GGA-200406 CPT1A,B transfers PALM to CAR IEA Gallus gallus 57384 R-GGA-200555 https://reactome.org/PathwayBrowser/#/R-GGA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Gallus gallus 57384 R-GGA-2046083 https://reactome.org/PathwayBrowser/#/R-GGA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Gallus gallus 57384 R-GGA-2046088 https://reactome.org/PathwayBrowser/#/R-GGA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Gallus gallus 57384 R-GGA-2046090 https://reactome.org/PathwayBrowser/#/R-GGA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 57384 R-GGA-2046094 https://reactome.org/PathwayBrowser/#/R-GGA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Gallus gallus 57384 R-GGA-2046095 https://reactome.org/PathwayBrowser/#/R-GGA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Gallus gallus 57384 R-GGA-2046100 https://reactome.org/PathwayBrowser/#/R-GGA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Gallus gallus 57384 R-GGA-548800 https://reactome.org/PathwayBrowser/#/R-GGA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Gallus gallus 57384 R-GGA-548814 https://reactome.org/PathwayBrowser/#/R-GGA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Gallus gallus 57384 R-GGA-548815 https://reactome.org/PathwayBrowser/#/R-GGA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Gallus gallus 57384 R-GGA-75851 https://reactome.org/PathwayBrowser/#/R-GGA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Gallus gallus 57384 R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Gallus gallus 57384 R-GGA-8933547 https://reactome.org/PathwayBrowser/#/R-GGA-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Gallus gallus 57384 R-GGA-977317 https://reactome.org/PathwayBrowser/#/R-GGA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Gallus gallus 57384 R-HSA-200406 https://reactome.org/PathwayBrowser/#/R-HSA-200406 CPT1A,B transfers PALM to CAR TAS Homo sapiens 57384 R-HSA-200555 https://reactome.org/PathwayBrowser/#/R-HSA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate TAS Homo sapiens 57384 R-HSA-2046083 https://reactome.org/PathwayBrowser/#/R-HSA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA TAS Homo sapiens 57384 R-HSA-2046088 https://reactome.org/PathwayBrowser/#/R-HSA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA TAS Homo sapiens 57384 R-HSA-2046090 https://reactome.org/PathwayBrowser/#/R-HSA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 57384 R-HSA-2046094 https://reactome.org/PathwayBrowser/#/R-HSA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA TAS Homo sapiens 57384 R-HSA-2046095 https://reactome.org/PathwayBrowser/#/R-HSA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA TAS Homo sapiens 57384 R-HSA-2046100 https://reactome.org/PathwayBrowser/#/R-HSA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA TAS Homo sapiens 57384 R-HSA-548800 https://reactome.org/PathwayBrowser/#/R-HSA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA TAS Homo sapiens 57384 R-HSA-548814 https://reactome.org/PathwayBrowser/#/R-HSA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA TAS Homo sapiens 57384 R-HSA-548815 https://reactome.org/PathwayBrowser/#/R-HSA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA TAS Homo sapiens 57384 R-HSA-548830 https://reactome.org/PathwayBrowser/#/R-HSA-548830 ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA IEA Homo sapiens 57384 R-HSA-75851 https://reactome.org/PathwayBrowser/#/R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 57384 R-HSA-75872 https://reactome.org/PathwayBrowser/#/R-HSA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O TAS Homo sapiens 57384 R-HSA-8876889 https://reactome.org/PathwayBrowser/#/R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 57384 R-HSA-8933547 https://reactome.org/PathwayBrowser/#/R-HSA-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 TAS Homo sapiens 57384 R-HSA-977317 https://reactome.org/PathwayBrowser/#/R-HSA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome TAS Homo sapiens 57384 R-MMU-200406 https://reactome.org/PathwayBrowser/#/R-MMU-200406 CPT1A,B transfers PALM to CAR IEA Mus musculus 57384 R-MMU-200555 https://reactome.org/PathwayBrowser/#/R-MMU-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Mus musculus 57384 R-MMU-2046083 https://reactome.org/PathwayBrowser/#/R-MMU-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Mus musculus 57384 R-MMU-2046088 https://reactome.org/PathwayBrowser/#/R-MMU-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Mus musculus 57384 R-MMU-2046090 https://reactome.org/PathwayBrowser/#/R-MMU-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 57384 R-MMU-2046094 https://reactome.org/PathwayBrowser/#/R-MMU-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Mus musculus 57384 R-MMU-2046095 https://reactome.org/PathwayBrowser/#/R-MMU-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Mus musculus 57384 R-MMU-2046100 https://reactome.org/PathwayBrowser/#/R-MMU-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Mus musculus 57384 R-MMU-548800 https://reactome.org/PathwayBrowser/#/R-MMU-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Mus musculus 57384 R-MMU-548814 https://reactome.org/PathwayBrowser/#/R-MMU-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Mus musculus 57384 R-MMU-548815 https://reactome.org/PathwayBrowser/#/R-MMU-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Mus musculus 57384 R-MMU-548848 https://reactome.org/PathwayBrowser/#/R-MMU-548848 lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4] TAS Mus musculus 57384 R-MMU-75851 https://reactome.org/PathwayBrowser/#/R-MMU-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 57384 R-MMU-75872 https://reactome.org/PathwayBrowser/#/R-MMU-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Mus musculus 57384 R-MMU-8876889 https://reactome.org/PathwayBrowser/#/R-MMU-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 57384 R-MMU-8933547 https://reactome.org/PathwayBrowser/#/R-MMU-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Mus musculus 57384 R-MMU-977317 https://reactome.org/PathwayBrowser/#/R-MMU-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Mus musculus 57384 R-PFA-200555 https://reactome.org/PathwayBrowser/#/R-PFA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Plasmodium falciparum 57384 R-PFA-2046088 https://reactome.org/PathwayBrowser/#/R-PFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Plasmodium falciparum 57384 R-PFA-2046094 https://reactome.org/PathwayBrowser/#/R-PFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Plasmodium falciparum 57384 R-PFA-548800 https://reactome.org/PathwayBrowser/#/R-PFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Plasmodium falciparum 57384 R-PFA-548814 https://reactome.org/PathwayBrowser/#/R-PFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Plasmodium falciparum 57384 R-PFA-75851 https://reactome.org/PathwayBrowser/#/R-PFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 57384 R-PFA-8876889 https://reactome.org/PathwayBrowser/#/R-PFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 57384 R-RNO-200406 https://reactome.org/PathwayBrowser/#/R-RNO-200406 CPT1A,B transfers PALM to CAR IEA Rattus norvegicus 57384 R-RNO-200555 https://reactome.org/PathwayBrowser/#/R-RNO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Rattus norvegicus 57384 R-RNO-2046083 https://reactome.org/PathwayBrowser/#/R-RNO-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Rattus norvegicus 57384 R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus 57384 R-RNO-2046090 https://reactome.org/PathwayBrowser/#/R-RNO-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 57384 R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus 57384 R-RNO-2046095 https://reactome.org/PathwayBrowser/#/R-RNO-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Rattus norvegicus 57384 R-RNO-2046100 https://reactome.org/PathwayBrowser/#/R-RNO-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Rattus norvegicus 57384 R-RNO-548800 https://reactome.org/PathwayBrowser/#/R-RNO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Rattus norvegicus 57384 R-RNO-548814 https://reactome.org/PathwayBrowser/#/R-RNO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Rattus norvegicus 57384 R-RNO-548815 https://reactome.org/PathwayBrowser/#/R-RNO-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Rattus norvegicus 57384 R-RNO-75851 https://reactome.org/PathwayBrowser/#/R-RNO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 57384 R-RNO-75872 https://reactome.org/PathwayBrowser/#/R-RNO-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Rattus norvegicus 57384 R-RNO-8876889 https://reactome.org/PathwayBrowser/#/R-RNO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 57384 R-RNO-8933547 https://reactome.org/PathwayBrowser/#/R-RNO-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Rattus norvegicus 57384 R-RNO-977317 https://reactome.org/PathwayBrowser/#/R-RNO-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Rattus norvegicus 57384 R-SCE-200555 https://reactome.org/PathwayBrowser/#/R-SCE-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Saccharomyces cerevisiae 57384 R-SCE-2046088 https://reactome.org/PathwayBrowser/#/R-SCE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Saccharomyces cerevisiae 57384 R-SCE-2046094 https://reactome.org/PathwayBrowser/#/R-SCE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Saccharomyces cerevisiae 57384 R-SCE-548800 https://reactome.org/PathwayBrowser/#/R-SCE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Saccharomyces cerevisiae 57384 R-SCE-548814 https://reactome.org/PathwayBrowser/#/R-SCE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Saccharomyces cerevisiae 57384 R-SCE-75851 https://reactome.org/PathwayBrowser/#/R-SCE-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 57384 R-SCE-8876889 https://reactome.org/PathwayBrowser/#/R-SCE-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 57384 R-SCE-8933547 https://reactome.org/PathwayBrowser/#/R-SCE-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Saccharomyces cerevisiae 57384 R-SPO-200555 https://reactome.org/PathwayBrowser/#/R-SPO-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Schizosaccharomyces pombe 57384 R-SPO-2046088 https://reactome.org/PathwayBrowser/#/R-SPO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Schizosaccharomyces pombe 57384 R-SPO-2046094 https://reactome.org/PathwayBrowser/#/R-SPO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Schizosaccharomyces pombe 57384 R-SPO-548800 https://reactome.org/PathwayBrowser/#/R-SPO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Schizosaccharomyces pombe 57384 R-SPO-548814 https://reactome.org/PathwayBrowser/#/R-SPO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Schizosaccharomyces pombe 57384 R-SPO-75851 https://reactome.org/PathwayBrowser/#/R-SPO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 57384 R-SPO-8876889 https://reactome.org/PathwayBrowser/#/R-SPO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 57384 R-SPO-8933547 https://reactome.org/PathwayBrowser/#/R-SPO-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Schizosaccharomyces pombe 57384 R-SSC-200406 https://reactome.org/PathwayBrowser/#/R-SSC-200406 CPT1A,B transfers PALM to CAR IEA Sus scrofa 57384 R-SSC-200555 https://reactome.org/PathwayBrowser/#/R-SSC-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Sus scrofa 57384 R-SSC-2046083 https://reactome.org/PathwayBrowser/#/R-SSC-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Sus scrofa 57384 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa 57384 R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 57384 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa 57384 R-SSC-2046095 https://reactome.org/PathwayBrowser/#/R-SSC-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Sus scrofa 57384 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa 57384 R-SSC-548800 https://reactome.org/PathwayBrowser/#/R-SSC-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Sus scrofa 57384 R-SSC-548814 https://reactome.org/PathwayBrowser/#/R-SSC-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Sus scrofa 57384 R-SSC-548815 https://reactome.org/PathwayBrowser/#/R-SSC-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Sus scrofa 57384 R-SSC-75851 https://reactome.org/PathwayBrowser/#/R-SSC-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 57384 R-SSC-75872 https://reactome.org/PathwayBrowser/#/R-SSC-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Sus scrofa 57384 R-SSC-8876889 https://reactome.org/PathwayBrowser/#/R-SSC-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 57384 R-SSC-8933547 https://reactome.org/PathwayBrowser/#/R-SSC-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Sus scrofa 57384 R-SSC-977317 https://reactome.org/PathwayBrowser/#/R-SSC-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Sus scrofa 57384 R-XTR-200406 https://reactome.org/PathwayBrowser/#/R-XTR-200406 CPT1A,B transfers PALM to CAR IEA Xenopus tropicalis 57384 R-XTR-200555 https://reactome.org/PathwayBrowser/#/R-XTR-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate IEA Xenopus tropicalis 57384 R-XTR-2046083 https://reactome.org/PathwayBrowser/#/R-XTR-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Xenopus tropicalis 57384 R-XTR-2046088 https://reactome.org/PathwayBrowser/#/R-XTR-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Xenopus tropicalis 57384 R-XTR-2046090 https://reactome.org/PathwayBrowser/#/R-XTR-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Xenopus tropicalis 57384 R-XTR-2046094 https://reactome.org/PathwayBrowser/#/R-XTR-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Xenopus tropicalis 57384 R-XTR-2046095 https://reactome.org/PathwayBrowser/#/R-XTR-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Xenopus tropicalis 57384 R-XTR-2046100 https://reactome.org/PathwayBrowser/#/R-XTR-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Xenopus tropicalis 57384 R-XTR-548800 https://reactome.org/PathwayBrowser/#/R-XTR-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Xenopus tropicalis 57384 R-XTR-548814 https://reactome.org/PathwayBrowser/#/R-XTR-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Xenopus tropicalis 57384 R-XTR-548815 https://reactome.org/PathwayBrowser/#/R-XTR-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Xenopus tropicalis 57384 R-XTR-75851 https://reactome.org/PathwayBrowser/#/R-XTR-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 57384 R-XTR-75872 https://reactome.org/PathwayBrowser/#/R-XTR-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Xenopus tropicalis 57384 R-XTR-8876889 https://reactome.org/PathwayBrowser/#/R-XTR-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 57384 R-XTR-977317 https://reactome.org/PathwayBrowser/#/R-XTR-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Xenopus tropicalis 57390 R-BTA-177157 https://reactome.org/PathwayBrowser/#/R-BTA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Bos taurus 57390 R-CFA-177157 https://reactome.org/PathwayBrowser/#/R-CFA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Canis familiaris 57390 R-DRE-177157 https://reactome.org/PathwayBrowser/#/R-DRE-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Danio rerio 57390 R-GGA-177157 https://reactome.org/PathwayBrowser/#/R-GGA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Gallus gallus 57390 R-HSA-177157 https://reactome.org/PathwayBrowser/#/R-HSA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate TAS Homo sapiens 57390 R-HSA-177160 https://reactome.org/PathwayBrowser/#/R-HSA-177160 phenylacetyl-CoA + glutamine => phenylacetyl glutamine + Coenzyme A TAS Homo sapiens 57390 R-MMU-177157 https://reactome.org/PathwayBrowser/#/R-MMU-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Mus musculus 57390 R-RNO-177157 https://reactome.org/PathwayBrowser/#/R-RNO-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 57390 R-SSC-177157 https://reactome.org/PathwayBrowser/#/R-SSC-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Sus scrofa 57390 R-XTR-177157 https://reactome.org/PathwayBrowser/#/R-XTR-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 57394 R-BTA-548831 https://reactome.org/PathwayBrowser/#/R-BTA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Bos taurus 57394 R-BTA-5690565 https://reactome.org/PathwayBrowser/#/R-BTA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Bos taurus 57394 R-BTA-8847579 https://reactome.org/PathwayBrowser/#/R-BTA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Bos taurus 57394 R-CEL-548831 https://reactome.org/PathwayBrowser/#/R-CEL-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Caenorhabditis elegans 57394 R-CEL-5690565 https://reactome.org/PathwayBrowser/#/R-CEL-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 57394 R-CEL-8847579 https://reactome.org/PathwayBrowser/#/R-CEL-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 57394 R-CFA-548831 https://reactome.org/PathwayBrowser/#/R-CFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Canis familiaris 57394 R-CFA-5690565 https://reactome.org/PathwayBrowser/#/R-CFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Canis familiaris 57394 R-CFA-8847579 https://reactome.org/PathwayBrowser/#/R-CFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Canis familiaris 57394 R-DDI-548831 https://reactome.org/PathwayBrowser/#/R-DDI-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Dictyostelium discoideum 57394 R-DDI-5690565 https://reactome.org/PathwayBrowser/#/R-DDI-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 57394 R-DDI-8847579 https://reactome.org/PathwayBrowser/#/R-DDI-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 57394 R-DME-548831 https://reactome.org/PathwayBrowser/#/R-DME-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Drosophila melanogaster 57394 R-DME-5690565 https://reactome.org/PathwayBrowser/#/R-DME-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 57394 R-DME-8847579 https://reactome.org/PathwayBrowser/#/R-DME-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 57394 R-DRE-5690565 https://reactome.org/PathwayBrowser/#/R-DRE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Danio rerio 57394 R-GGA-433592 https://reactome.org/PathwayBrowser/#/R-GGA-433592 sphinganine + stearyl-CoA => dihydroceramide + CoASH IEA Gallus gallus 57394 R-GGA-548831 https://reactome.org/PathwayBrowser/#/R-GGA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Gallus gallus 57394 R-GGA-5690565 https://reactome.org/PathwayBrowser/#/R-GGA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Gallus gallus 57394 R-GGA-8847579 https://reactome.org/PathwayBrowser/#/R-GGA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Gallus gallus 57394 R-HSA-548831 https://reactome.org/PathwayBrowser/#/R-HSA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA TAS Homo sapiens 57394 R-HSA-5690565 https://reactome.org/PathwayBrowser/#/R-HSA-5690565 SCD desaturates ST-CoA to OLE-CoA TAS Homo sapiens 57394 R-HSA-8847579 https://reactome.org/PathwayBrowser/#/R-HSA-8847579 SCD5 desaturates ST-CoA to OLE-CoA TAS Homo sapiens 57394 R-MMU-548831 https://reactome.org/PathwayBrowser/#/R-MMU-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Mus musculus 57394 R-MMU-5690565 https://reactome.org/PathwayBrowser/#/R-MMU-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Mus musculus 57394 R-PFA-548831 https://reactome.org/PathwayBrowser/#/R-PFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Plasmodium falciparum 57394 R-PFA-5690565 https://reactome.org/PathwayBrowser/#/R-PFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 57394 R-PFA-8847579 https://reactome.org/PathwayBrowser/#/R-PFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 57394 R-RNO-548831 https://reactome.org/PathwayBrowser/#/R-RNO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Rattus norvegicus 57394 R-RNO-5690565 https://reactome.org/PathwayBrowser/#/R-RNO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Rattus norvegicus 57394 R-SCE-548831 https://reactome.org/PathwayBrowser/#/R-SCE-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Saccharomyces cerevisiae 57394 R-SCE-5690565 https://reactome.org/PathwayBrowser/#/R-SCE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 57394 R-SCE-8847579 https://reactome.org/PathwayBrowser/#/R-SCE-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 57394 R-SPO-548831 https://reactome.org/PathwayBrowser/#/R-SPO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Schizosaccharomyces pombe 57394 R-SPO-5690565 https://reactome.org/PathwayBrowser/#/R-SPO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 57394 R-SPO-8847579 https://reactome.org/PathwayBrowser/#/R-SPO-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 57394 R-SSC-548831 https://reactome.org/PathwayBrowser/#/R-SSC-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Sus scrofa 57394 R-SSC-5690565 https://reactome.org/PathwayBrowser/#/R-SSC-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Sus scrofa 57394 R-SSC-8847579 https://reactome.org/PathwayBrowser/#/R-SSC-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Sus scrofa 57394 R-XTR-548831 https://reactome.org/PathwayBrowser/#/R-XTR-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Xenopus tropicalis 57394 R-XTR-5690565 https://reactome.org/PathwayBrowser/#/R-XTR-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Xenopus tropicalis 57427 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 57427 R-BTA-352103 https://reactome.org/PathwayBrowser/#/R-BTA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Bos taurus 57427 R-BTA-352107 https://reactome.org/PathwayBrowser/#/R-BTA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Bos taurus 57427 R-BTA-352108 https://reactome.org/PathwayBrowser/#/R-BTA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Bos taurus 57427 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 57427 R-BTA-352232 https://reactome.org/PathwayBrowser/#/R-BTA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Bos taurus 57427 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 57427 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 57427 R-BTA-379415 https://reactome.org/PathwayBrowser/#/R-BTA-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Bos taurus 57427 R-BTA-379426 https://reactome.org/PathwayBrowser/#/R-BTA-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Bos taurus 57427 R-BTA-379432 https://reactome.org/PathwayBrowser/#/R-BTA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Bos taurus 57427 R-BTA-508179 https://reactome.org/PathwayBrowser/#/R-BTA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Bos taurus 57427 R-BTA-508189 https://reactome.org/PathwayBrowser/#/R-BTA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Bos taurus 57427 R-BTA-70723 https://reactome.org/PathwayBrowser/#/R-BTA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Bos taurus 57427 R-BTA-70724 https://reactome.org/PathwayBrowser/#/R-BTA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Bos taurus 57427 R-BTA-9639287 https://reactome.org/PathwayBrowser/#/R-BTA-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Bos taurus 57427 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 57427 R-CEL-508179 https://reactome.org/PathwayBrowser/#/R-CEL-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Caenorhabditis elegans 57427 R-CEL-508189 https://reactome.org/PathwayBrowser/#/R-CEL-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Caenorhabditis elegans 57427 R-CEL-70723 https://reactome.org/PathwayBrowser/#/R-CEL-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Caenorhabditis elegans 57427 R-CEL-70724 https://reactome.org/PathwayBrowser/#/R-CEL-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Caenorhabditis elegans 57427 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 57427 R-CFA-352103 https://reactome.org/PathwayBrowser/#/R-CFA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Canis familiaris 57427 R-CFA-352107 https://reactome.org/PathwayBrowser/#/R-CFA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Canis familiaris 57427 R-CFA-352108 https://reactome.org/PathwayBrowser/#/R-CFA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Canis familiaris 57427 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 57427 R-CFA-352232 https://reactome.org/PathwayBrowser/#/R-CFA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Canis familiaris 57427 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 57427 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 57427 R-CFA-379426 https://reactome.org/PathwayBrowser/#/R-CFA-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Canis familiaris 57427 R-CFA-379432 https://reactome.org/PathwayBrowser/#/R-CFA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Canis familiaris 57427 R-CFA-508179 https://reactome.org/PathwayBrowser/#/R-CFA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Canis familiaris 57427 R-CFA-508189 https://reactome.org/PathwayBrowser/#/R-CFA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Canis familiaris 57427 R-CFA-70723 https://reactome.org/PathwayBrowser/#/R-CFA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Canis familiaris 57427 R-CFA-70724 https://reactome.org/PathwayBrowser/#/R-CFA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Canis familiaris 57427 R-CFA-9639287 https://reactome.org/PathwayBrowser/#/R-CFA-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Canis familiaris 57427 R-DDI-508179 https://reactome.org/PathwayBrowser/#/R-DDI-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Dictyostelium discoideum 57427 R-DDI-508189 https://reactome.org/PathwayBrowser/#/R-DDI-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Dictyostelium discoideum 57427 R-DDI-70723 https://reactome.org/PathwayBrowser/#/R-DDI-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Dictyostelium discoideum 57427 R-DDI-70724 https://reactome.org/PathwayBrowser/#/R-DDI-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Dictyostelium discoideum 57427 R-DDI-9639287 https://reactome.org/PathwayBrowser/#/R-DDI-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Dictyostelium discoideum 57427 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 57427 R-DME-352108 https://reactome.org/PathwayBrowser/#/R-DME-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57427 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57427 R-DME-352232 https://reactome.org/PathwayBrowser/#/R-DME-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Drosophila melanogaster 57427 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57427 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57427 R-DME-379415 https://reactome.org/PathwayBrowser/#/R-DME-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Drosophila melanogaster 57427 R-DME-379426 https://reactome.org/PathwayBrowser/#/R-DME-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Drosophila melanogaster 57427 R-DME-379432 https://reactome.org/PathwayBrowser/#/R-DME-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Drosophila melanogaster 57427 R-DME-508179 https://reactome.org/PathwayBrowser/#/R-DME-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Drosophila melanogaster 57427 R-DME-508189 https://reactome.org/PathwayBrowser/#/R-DME-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Drosophila melanogaster 57427 R-DME-70723 https://reactome.org/PathwayBrowser/#/R-DME-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Drosophila melanogaster 57427 R-DME-70724 https://reactome.org/PathwayBrowser/#/R-DME-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Drosophila melanogaster 57427 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 57427 R-DRE-352103 https://reactome.org/PathwayBrowser/#/R-DRE-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Danio rerio 57427 R-DRE-352108 https://reactome.org/PathwayBrowser/#/R-DRE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Danio rerio 57427 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 57427 R-DRE-379415 https://reactome.org/PathwayBrowser/#/R-DRE-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Danio rerio 57427 R-DRE-379426 https://reactome.org/PathwayBrowser/#/R-DRE-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Danio rerio 57427 R-DRE-508179 https://reactome.org/PathwayBrowser/#/R-DRE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Danio rerio 57427 R-DRE-508189 https://reactome.org/PathwayBrowser/#/R-DRE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Danio rerio 57427 R-DRE-70723 https://reactome.org/PathwayBrowser/#/R-DRE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Danio rerio 57427 R-DRE-70724 https://reactome.org/PathwayBrowser/#/R-DRE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Danio rerio 57427 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 57427 R-GGA-352107 https://reactome.org/PathwayBrowser/#/R-GGA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Gallus gallus 57427 R-GGA-352108 https://reactome.org/PathwayBrowser/#/R-GGA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Gallus gallus 57427 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 57427 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 57427 R-GGA-379432 https://reactome.org/PathwayBrowser/#/R-GGA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Gallus gallus 57427 R-GGA-508189 https://reactome.org/PathwayBrowser/#/R-GGA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Gallus gallus 57427 R-GGA-70723 https://reactome.org/PathwayBrowser/#/R-GGA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Gallus gallus 57427 R-GGA-9639287 https://reactome.org/PathwayBrowser/#/R-GGA-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Gallus gallus 57427 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 57427 R-HSA-352103 https://reactome.org/PathwayBrowser/#/R-HSA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids TAS Homo sapiens 57427 R-HSA-352107 https://reactome.org/PathwayBrowser/#/R-HSA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids TAS Homo sapiens 57427 R-HSA-352108 https://reactome.org/PathwayBrowser/#/R-HSA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids TAS Homo sapiens 57427 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 57427 R-HSA-352232 https://reactome.org/PathwayBrowser/#/R-HSA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol TAS Homo sapiens 57427 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57427 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57427 R-HSA-379415 https://reactome.org/PathwayBrowser/#/R-HSA-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane TAS Homo sapiens 57427 R-HSA-379426 https://reactome.org/PathwayBrowser/#/R-HSA-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine TAS Homo sapiens 57427 R-HSA-379432 https://reactome.org/PathwayBrowser/#/R-HSA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 57427 R-HSA-379974 https://reactome.org/PathwayBrowser/#/R-HSA-379974 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 57427 R-HSA-380200 https://reactome.org/PathwayBrowser/#/R-HSA-380200 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate TAS Homo sapiens 57427 R-HSA-508179 https://reactome.org/PathwayBrowser/#/R-HSA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] TAS Homo sapiens 57427 R-HSA-508189 https://reactome.org/PathwayBrowser/#/R-HSA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] TAS Homo sapiens 57427 R-HSA-5655702 https://reactome.org/PathwayBrowser/#/R-HSA-5655702 Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 57427 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57427 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57427 R-HSA-5660890 https://reactome.org/PathwayBrowser/#/R-HSA-5660890 Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu TAS Homo sapiens 57427 R-HSA-5660910 https://reactome.org/PathwayBrowser/#/R-HSA-5660910 Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane TAS Homo sapiens 57427 R-HSA-70723 https://reactome.org/PathwayBrowser/#/R-HSA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] TAS Homo sapiens 57427 R-HSA-70724 https://reactome.org/PathwayBrowser/#/R-HSA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] TAS Homo sapiens 57427 R-HSA-9639287 https://reactome.org/PathwayBrowser/#/R-HSA-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 TAS Homo sapiens 57427 R-HSA-9672770 https://reactome.org/PathwayBrowser/#/R-HSA-9672770 SLC25A44 transports Leu, Ile and Val from cytosol to mitochondrial matrix IEA Homo sapiens 57427 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 57427 R-MMU-352103 https://reactome.org/PathwayBrowser/#/R-MMU-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Mus musculus 57427 R-MMU-352107 https://reactome.org/PathwayBrowser/#/R-MMU-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Mus musculus 57427 R-MMU-352108 https://reactome.org/PathwayBrowser/#/R-MMU-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Mus musculus 57427 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 57427 R-MMU-352232 https://reactome.org/PathwayBrowser/#/R-MMU-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Mus musculus 57427 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 57427 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 57427 R-MMU-379415 https://reactome.org/PathwayBrowser/#/R-MMU-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Mus musculus 57427 R-MMU-379426 https://reactome.org/PathwayBrowser/#/R-MMU-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Mus musculus 57427 R-MMU-379432 https://reactome.org/PathwayBrowser/#/R-MMU-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Mus musculus 57427 R-MMU-508179 https://reactome.org/PathwayBrowser/#/R-MMU-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Mus musculus 57427 R-MMU-508189 https://reactome.org/PathwayBrowser/#/R-MMU-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Mus musculus 57427 R-MMU-70723 https://reactome.org/PathwayBrowser/#/R-MMU-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Mus musculus 57427 R-MMU-70724 https://reactome.org/PathwayBrowser/#/R-MMU-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Mus musculus 57427 R-MMU-9639287 https://reactome.org/PathwayBrowser/#/R-MMU-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Mus musculus 57427 R-MMU-9673827 https://reactome.org/PathwayBrowser/#/R-MMU-9673827 Slc25a44 transports Leu, Ile and Val from cytosol to mitochondrial matrix TAS Mus musculus 57427 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 57427 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57427 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57427 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 57427 R-RNO-352103 https://reactome.org/PathwayBrowser/#/R-RNO-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Rattus norvegicus 57427 R-RNO-352107 https://reactome.org/PathwayBrowser/#/R-RNO-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Rattus norvegicus 57427 R-RNO-352108 https://reactome.org/PathwayBrowser/#/R-RNO-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Rattus norvegicus 57427 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 57427 R-RNO-352232 https://reactome.org/PathwayBrowser/#/R-RNO-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Rattus norvegicus 57427 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 57427 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 57427 R-RNO-379415 https://reactome.org/PathwayBrowser/#/R-RNO-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Rattus norvegicus 57427 R-RNO-379426 https://reactome.org/PathwayBrowser/#/R-RNO-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Rattus norvegicus 57427 R-RNO-379432 https://reactome.org/PathwayBrowser/#/R-RNO-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Rattus norvegicus 57427 R-RNO-508179 https://reactome.org/PathwayBrowser/#/R-RNO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Rattus norvegicus 57427 R-RNO-508189 https://reactome.org/PathwayBrowser/#/R-RNO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Rattus norvegicus 57427 R-RNO-70723 https://reactome.org/PathwayBrowser/#/R-RNO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Rattus norvegicus 57427 R-RNO-70724 https://reactome.org/PathwayBrowser/#/R-RNO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Rattus norvegicus 57427 R-RNO-9639287 https://reactome.org/PathwayBrowser/#/R-RNO-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Rattus norvegicus 57427 R-SCE-352108 https://reactome.org/PathwayBrowser/#/R-SCE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 57427 R-SCE-379432 https://reactome.org/PathwayBrowser/#/R-SCE-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Saccharomyces cerevisiae 57427 R-SCE-508179 https://reactome.org/PathwayBrowser/#/R-SCE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Saccharomyces cerevisiae 57427 R-SCE-508189 https://reactome.org/PathwayBrowser/#/R-SCE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Saccharomyces cerevisiae 57427 R-SCE-70723 https://reactome.org/PathwayBrowser/#/R-SCE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Saccharomyces cerevisiae 57427 R-SCE-70724 https://reactome.org/PathwayBrowser/#/R-SCE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Saccharomyces cerevisiae 57427 R-SPO-508179 https://reactome.org/PathwayBrowser/#/R-SPO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Schizosaccharomyces pombe 57427 R-SPO-508189 https://reactome.org/PathwayBrowser/#/R-SPO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Schizosaccharomyces pombe 57427 R-SPO-70723 https://reactome.org/PathwayBrowser/#/R-SPO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Schizosaccharomyces pombe 57427 R-SPO-70724 https://reactome.org/PathwayBrowser/#/R-SPO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Schizosaccharomyces pombe 57427 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 57427 R-SSC-352103 https://reactome.org/PathwayBrowser/#/R-SSC-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Sus scrofa 57427 R-SSC-352107 https://reactome.org/PathwayBrowser/#/R-SSC-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Sus scrofa 57427 R-SSC-352108 https://reactome.org/PathwayBrowser/#/R-SSC-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Sus scrofa 57427 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 57427 R-SSC-352232 https://reactome.org/PathwayBrowser/#/R-SSC-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Sus scrofa 57427 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 57427 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 57427 R-SSC-379415 https://reactome.org/PathwayBrowser/#/R-SSC-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Sus scrofa 57427 R-SSC-379432 https://reactome.org/PathwayBrowser/#/R-SSC-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Sus scrofa 57427 R-SSC-508179 https://reactome.org/PathwayBrowser/#/R-SSC-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Sus scrofa 57427 R-SSC-508189 https://reactome.org/PathwayBrowser/#/R-SSC-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Sus scrofa 57427 R-SSC-70723 https://reactome.org/PathwayBrowser/#/R-SSC-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Sus scrofa 57427 R-SSC-70724 https://reactome.org/PathwayBrowser/#/R-SSC-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Sus scrofa 57427 R-SSC-9639287 https://reactome.org/PathwayBrowser/#/R-SSC-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Sus scrofa 57427 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 57427 R-XTR-352103 https://reactome.org/PathwayBrowser/#/R-XTR-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Xenopus tropicalis 57427 R-XTR-352107 https://reactome.org/PathwayBrowser/#/R-XTR-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Xenopus tropicalis 57427 R-XTR-352108 https://reactome.org/PathwayBrowser/#/R-XTR-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57427 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57427 R-XTR-352232 https://reactome.org/PathwayBrowser/#/R-XTR-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Xenopus tropicalis 57427 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57427 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57427 R-XTR-379415 https://reactome.org/PathwayBrowser/#/R-XTR-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Xenopus tropicalis 57427 R-XTR-379426 https://reactome.org/PathwayBrowser/#/R-XTR-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Xenopus tropicalis 57427 R-XTR-379432 https://reactome.org/PathwayBrowser/#/R-XTR-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu IEA Xenopus tropicalis 57427 R-XTR-508179 https://reactome.org/PathwayBrowser/#/R-XTR-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Xenopus tropicalis 57427 R-XTR-508189 https://reactome.org/PathwayBrowser/#/R-XTR-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Xenopus tropicalis 57427 R-XTR-70723 https://reactome.org/PathwayBrowser/#/R-XTR-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Xenopus tropicalis 57427 R-XTR-70724 https://reactome.org/PathwayBrowser/#/R-XTR-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Xenopus tropicalis 57427 R-XTR-9639287 https://reactome.org/PathwayBrowser/#/R-XTR-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Xenopus tropicalis 57433 R-BTA-6797653 https://reactome.org/PathwayBrowser/#/R-BTA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Bos taurus 57433 R-BTA-6797913 https://reactome.org/PathwayBrowser/#/R-BTA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Bos taurus 57433 R-BTA-6798317 https://reactome.org/PathwayBrowser/#/R-BTA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Bos taurus 57433 R-CEL-6797653 https://reactome.org/PathwayBrowser/#/R-CEL-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Caenorhabditis elegans 57433 R-CFA-6797653 https://reactome.org/PathwayBrowser/#/R-CFA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Canis familiaris 57433 R-CFA-6797913 https://reactome.org/PathwayBrowser/#/R-CFA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Canis familiaris 57433 R-CFA-6798317 https://reactome.org/PathwayBrowser/#/R-CFA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Canis familiaris 57433 R-DME-6797913 https://reactome.org/PathwayBrowser/#/R-DME-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Drosophila melanogaster 57433 R-DME-6798317 https://reactome.org/PathwayBrowser/#/R-DME-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Drosophila melanogaster 57433 R-DRE-6797913 https://reactome.org/PathwayBrowser/#/R-DRE-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Danio rerio 57433 R-DRE-6798317 https://reactome.org/PathwayBrowser/#/R-DRE-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Danio rerio 57433 R-GGA-6797653 https://reactome.org/PathwayBrowser/#/R-GGA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Gallus gallus 57433 R-GGA-6797913 https://reactome.org/PathwayBrowser/#/R-GGA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Gallus gallus 57433 R-HSA-2408544 https://reactome.org/PathwayBrowser/#/R-HSA-2408544 AdoSeMet is converted to AdeSeHCys by MetTrans(1) IEA Homo sapiens 57433 R-HSA-6797653 https://reactome.org/PathwayBrowser/#/R-HSA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC TAS Homo sapiens 57433 R-HSA-6797913 https://reactome.org/PathwayBrowser/#/R-HSA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly TAS Homo sapiens 57433 R-HSA-6798317 https://reactome.org/PathwayBrowser/#/R-HSA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC TAS Homo sapiens 57433 R-MMU-6797653 https://reactome.org/PathwayBrowser/#/R-MMU-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Mus musculus 57433 R-MMU-6797913 https://reactome.org/PathwayBrowser/#/R-MMU-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Mus musculus 57433 R-MMU-6798317 https://reactome.org/PathwayBrowser/#/R-MMU-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Mus musculus 57433 R-RNO-2408545 https://reactome.org/PathwayBrowser/#/R-RNO-2408545 AdoSeMet is converted to AdeSeHCys by MetTrans(2) TAS Rattus norvegicus 57433 R-RNO-6797653 https://reactome.org/PathwayBrowser/#/R-RNO-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Rattus norvegicus 57433 R-RNO-6797913 https://reactome.org/PathwayBrowser/#/R-RNO-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Rattus norvegicus 57433 R-RNO-6798317 https://reactome.org/PathwayBrowser/#/R-RNO-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Rattus norvegicus 57433 R-SSC-6797653 https://reactome.org/PathwayBrowser/#/R-SSC-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Sus scrofa 57433 R-SSC-6797913 https://reactome.org/PathwayBrowser/#/R-SSC-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Sus scrofa 57433 R-SSC-6798317 https://reactome.org/PathwayBrowser/#/R-SSC-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Sus scrofa 57433 R-XTR-6798317 https://reactome.org/PathwayBrowser/#/R-XTR-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Xenopus tropicalis 57441 R-HSA-9640307 https://reactome.org/PathwayBrowser/#/R-HSA-9640307 DeHA hydrolyses to 2,3-DKG TAS Homo sapiens 57441 R-HSA-9640321 https://reactome.org/PathwayBrowser/#/R-HSA-9640321 2,3-DKG hydrolyses to ERU and oxalate TAS Homo sapiens 57443 R-BTA-351210 https://reactome.org/PathwayBrowser/#/R-BTA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Bos taurus 57443 R-BTA-351215 https://reactome.org/PathwayBrowser/#/R-BTA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Bos taurus 57443 R-BTA-351222 https://reactome.org/PathwayBrowser/#/R-BTA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Bos taurus 57443 R-CEL-351215 https://reactome.org/PathwayBrowser/#/R-CEL-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Caenorhabditis elegans 57443 R-CEL-351222 https://reactome.org/PathwayBrowser/#/R-CEL-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Caenorhabditis elegans 57443 R-CFA-351210 https://reactome.org/PathwayBrowser/#/R-CFA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Canis familiaris 57443 R-CFA-351215 https://reactome.org/PathwayBrowser/#/R-CFA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Canis familiaris 57443 R-CFA-351222 https://reactome.org/PathwayBrowser/#/R-CFA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Canis familiaris 57443 R-DDI-351215 https://reactome.org/PathwayBrowser/#/R-DDI-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Dictyostelium discoideum 57443 R-DDI-351222 https://reactome.org/PathwayBrowser/#/R-DDI-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Dictyostelium discoideum 57443 R-DME-351210 https://reactome.org/PathwayBrowser/#/R-DME-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Drosophila melanogaster 57443 R-DME-351215 https://reactome.org/PathwayBrowser/#/R-DME-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Drosophila melanogaster 57443 R-DME-351222 https://reactome.org/PathwayBrowser/#/R-DME-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Drosophila melanogaster 57443 R-DRE-351210 https://reactome.org/PathwayBrowser/#/R-DRE-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Danio rerio 57443 R-DRE-351222 https://reactome.org/PathwayBrowser/#/R-DRE-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Danio rerio 57443 R-GGA-351210 https://reactome.org/PathwayBrowser/#/R-GGA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Gallus gallus 57443 R-GGA-351215 https://reactome.org/PathwayBrowser/#/R-GGA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Gallus gallus 57443 R-GGA-351222 https://reactome.org/PathwayBrowser/#/R-GGA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Gallus gallus 57443 R-HSA-351210 https://reactome.org/PathwayBrowser/#/R-HSA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine TAS Homo sapiens 57443 R-HSA-351215 https://reactome.org/PathwayBrowser/#/R-HSA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine TAS Homo sapiens 57443 R-HSA-351222 https://reactome.org/PathwayBrowser/#/R-HSA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 TAS Homo sapiens 57443 R-MMU-351210 https://reactome.org/PathwayBrowser/#/R-MMU-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Mus musculus 57443 R-MMU-351215 https://reactome.org/PathwayBrowser/#/R-MMU-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Mus musculus 57443 R-MMU-351222 https://reactome.org/PathwayBrowser/#/R-MMU-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Mus musculus 57443 R-PFA-351215 https://reactome.org/PathwayBrowser/#/R-PFA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Plasmodium falciparum 57443 R-RNO-351210 https://reactome.org/PathwayBrowser/#/R-RNO-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Rattus norvegicus 57443 R-RNO-351215 https://reactome.org/PathwayBrowser/#/R-RNO-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Rattus norvegicus 57443 R-RNO-351222 https://reactome.org/PathwayBrowser/#/R-RNO-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Rattus norvegicus 57443 R-SCE-351215 https://reactome.org/PathwayBrowser/#/R-SCE-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Saccharomyces cerevisiae 57443 R-SCE-351222 https://reactome.org/PathwayBrowser/#/R-SCE-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Saccharomyces cerevisiae 57443 R-SPO-351215 https://reactome.org/PathwayBrowser/#/R-SPO-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Schizosaccharomyces pombe 57443 R-SPO-351222 https://reactome.org/PathwayBrowser/#/R-SPO-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Schizosaccharomyces pombe 57443 R-SSC-351210 https://reactome.org/PathwayBrowser/#/R-SSC-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Sus scrofa 57443 R-SSC-351215 https://reactome.org/PathwayBrowser/#/R-SSC-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Sus scrofa 57443 R-SSC-351222 https://reactome.org/PathwayBrowser/#/R-SSC-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Sus scrofa 57443 R-XTR-351210 https://reactome.org/PathwayBrowser/#/R-XTR-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Xenopus tropicalis 57443 R-XTR-351215 https://reactome.org/PathwayBrowser/#/R-XTR-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Xenopus tropicalis 57443 R-XTR-351222 https://reactome.org/PathwayBrowser/#/R-XTR-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Xenopus tropicalis 57451 R-BTA-197963 https://reactome.org/PathwayBrowser/#/R-BTA-197963 DHFR2 reduces FOLA to DHF IEA Bos taurus 57451 R-BTA-197972 https://reactome.org/PathwayBrowser/#/R-BTA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Bos taurus 57451 R-BTA-73605 https://reactome.org/PathwayBrowser/#/R-BTA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Bos taurus 57451 R-BTA-9709098 https://reactome.org/PathwayBrowser/#/R-BTA-9709098 DHFR dimer reduces FOLA to DHF IEA Bos taurus 57451 R-CEL-197963 https://reactome.org/PathwayBrowser/#/R-CEL-197963 DHFR2 reduces FOLA to DHF IEA Caenorhabditis elegans 57451 R-CEL-197972 https://reactome.org/PathwayBrowser/#/R-CEL-197972 DHF is reduced to tetrahydrofolate (THF) IEA Caenorhabditis elegans 57451 R-CEL-73605 https://reactome.org/PathwayBrowser/#/R-CEL-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Caenorhabditis elegans 57451 R-CEL-9709098 https://reactome.org/PathwayBrowser/#/R-CEL-9709098 DHFR dimer reduces FOLA to DHF IEA Caenorhabditis elegans 57451 R-CFA-197963 https://reactome.org/PathwayBrowser/#/R-CFA-197963 DHFR2 reduces FOLA to DHF IEA Canis familiaris 57451 R-CFA-197972 https://reactome.org/PathwayBrowser/#/R-CFA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Canis familiaris 57451 R-CFA-73605 https://reactome.org/PathwayBrowser/#/R-CFA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Canis familiaris 57451 R-CFA-9709098 https://reactome.org/PathwayBrowser/#/R-CFA-9709098 DHFR dimer reduces FOLA to DHF IEA Canis familiaris 57451 R-DDI-197963 https://reactome.org/PathwayBrowser/#/R-DDI-197963 DHFR2 reduces FOLA to DHF IEA Dictyostelium discoideum 57451 R-DDI-197972 https://reactome.org/PathwayBrowser/#/R-DDI-197972 DHF is reduced to tetrahydrofolate (THF) IEA Dictyostelium discoideum 57451 R-DDI-9709098 https://reactome.org/PathwayBrowser/#/R-DDI-9709098 DHFR dimer reduces FOLA to DHF IEA Dictyostelium discoideum 57451 R-DME-197963 https://reactome.org/PathwayBrowser/#/R-DME-197963 DHFR2 reduces FOLA to DHF IEA Drosophila melanogaster 57451 R-DME-197972 https://reactome.org/PathwayBrowser/#/R-DME-197972 DHF is reduced to tetrahydrofolate (THF) IEA Drosophila melanogaster 57451 R-DME-73605 https://reactome.org/PathwayBrowser/#/R-DME-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Drosophila melanogaster 57451 R-DME-9709098 https://reactome.org/PathwayBrowser/#/R-DME-9709098 DHFR dimer reduces FOLA to DHF IEA Drosophila melanogaster 57451 R-DRE-197963 https://reactome.org/PathwayBrowser/#/R-DRE-197963 DHFR2 reduces FOLA to DHF IEA Danio rerio 57451 R-DRE-197972 https://reactome.org/PathwayBrowser/#/R-DRE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Danio rerio 57451 R-DRE-73605 https://reactome.org/PathwayBrowser/#/R-DRE-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Danio rerio 57451 R-DRE-9709098 https://reactome.org/PathwayBrowser/#/R-DRE-9709098 DHFR dimer reduces FOLA to DHF IEA Danio rerio 57451 R-GGA-197963 https://reactome.org/PathwayBrowser/#/R-GGA-197963 DHFR2 reduces FOLA to DHF IEA Gallus gallus 57451 R-GGA-197972 https://reactome.org/PathwayBrowser/#/R-GGA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Gallus gallus 57451 R-GGA-9709098 https://reactome.org/PathwayBrowser/#/R-GGA-9709098 DHFR dimer reduces FOLA to DHF IEA Gallus gallus 57451 R-HSA-197963 https://reactome.org/PathwayBrowser/#/R-HSA-197963 DHFR2 reduces FOLA to DHF TAS Homo sapiens 57451 R-HSA-197972 https://reactome.org/PathwayBrowser/#/R-HSA-197972 DHF is reduced to tetrahydrofolate (THF) TAS Homo sapiens 57451 R-HSA-73605 https://reactome.org/PathwayBrowser/#/R-HSA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate TAS Homo sapiens 57451 R-HSA-9709098 https://reactome.org/PathwayBrowser/#/R-HSA-9709098 DHFR dimer reduces FOLA to DHF TAS Homo sapiens 57451 R-MMU-197963 https://reactome.org/PathwayBrowser/#/R-MMU-197963 DHFR2 reduces FOLA to DHF IEA Mus musculus 57451 R-MMU-197972 https://reactome.org/PathwayBrowser/#/R-MMU-197972 DHF is reduced to tetrahydrofolate (THF) IEA Mus musculus 57451 R-MMU-73605 https://reactome.org/PathwayBrowser/#/R-MMU-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Mus musculus 57451 R-MMU-9709098 https://reactome.org/PathwayBrowser/#/R-MMU-9709098 DHFR dimer reduces FOLA to DHF IEA Mus musculus 57451 R-PFA-73605 https://reactome.org/PathwayBrowser/#/R-PFA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Plasmodium falciparum 57451 R-RNO-197963 https://reactome.org/PathwayBrowser/#/R-RNO-197963 DHFR2 reduces FOLA to DHF IEA Rattus norvegicus 57451 R-RNO-197972 https://reactome.org/PathwayBrowser/#/R-RNO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Rattus norvegicus 57451 R-RNO-73605 https://reactome.org/PathwayBrowser/#/R-RNO-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Rattus norvegicus 57451 R-RNO-9709098 https://reactome.org/PathwayBrowser/#/R-RNO-9709098 DHFR dimer reduces FOLA to DHF IEA Rattus norvegicus 57451 R-SCE-197963 https://reactome.org/PathwayBrowser/#/R-SCE-197963 DHFR2 reduces FOLA to DHF IEA Saccharomyces cerevisiae 57451 R-SCE-197972 https://reactome.org/PathwayBrowser/#/R-SCE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Saccharomyces cerevisiae 57451 R-SCE-73605 https://reactome.org/PathwayBrowser/#/R-SCE-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Saccharomyces cerevisiae 57451 R-SCE-9709098 https://reactome.org/PathwayBrowser/#/R-SCE-9709098 DHFR dimer reduces FOLA to DHF IEA Saccharomyces cerevisiae 57451 R-SPO-197963 https://reactome.org/PathwayBrowser/#/R-SPO-197963 DHFR2 reduces FOLA to DHF IEA Schizosaccharomyces pombe 57451 R-SPO-197972 https://reactome.org/PathwayBrowser/#/R-SPO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Schizosaccharomyces pombe 57451 R-SPO-73605 https://reactome.org/PathwayBrowser/#/R-SPO-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Schizosaccharomyces pombe 57451 R-SPO-9709098 https://reactome.org/PathwayBrowser/#/R-SPO-9709098 DHFR dimer reduces FOLA to DHF IEA Schizosaccharomyces pombe 57451 R-SSC-197963 https://reactome.org/PathwayBrowser/#/R-SSC-197963 DHFR2 reduces FOLA to DHF IEA Sus scrofa 57451 R-SSC-197972 https://reactome.org/PathwayBrowser/#/R-SSC-197972 DHF is reduced to tetrahydrofolate (THF) IEA Sus scrofa 57451 R-SSC-73605 https://reactome.org/PathwayBrowser/#/R-SSC-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Sus scrofa 57451 R-SSC-9709098 https://reactome.org/PathwayBrowser/#/R-SSC-9709098 DHFR dimer reduces FOLA to DHF IEA Sus scrofa 57451 R-XTR-73605 https://reactome.org/PathwayBrowser/#/R-XTR-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Xenopus tropicalis 57453 R-BTA-197958 https://reactome.org/PathwayBrowser/#/R-BTA-197958 FPGS-2 transforms THF to THFPG IEA Bos taurus 57453 R-BTA-197972 https://reactome.org/PathwayBrowser/#/R-BTA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Bos taurus 57453 R-BTA-200680 https://reactome.org/PathwayBrowser/#/R-BTA-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Bos taurus 57453 R-BTA-200720 https://reactome.org/PathwayBrowser/#/R-BTA-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Bos taurus 57453 R-BTA-3149539 https://reactome.org/PathwayBrowser/#/R-BTA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Bos taurus 57453 R-BTA-70920 https://reactome.org/PathwayBrowser/#/R-BTA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Bos taurus 57453 R-BTA-73605 https://reactome.org/PathwayBrowser/#/R-BTA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Bos taurus 57453 R-BTA-73798 https://reactome.org/PathwayBrowser/#/R-BTA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Bos taurus 57453 R-BTA-73813 https://reactome.org/PathwayBrowser/#/R-BTA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Bos taurus 57453 R-CEL-197958 https://reactome.org/PathwayBrowser/#/R-CEL-197958 FPGS-2 transforms THF to THFPG IEA Caenorhabditis elegans 57453 R-CEL-197972 https://reactome.org/PathwayBrowser/#/R-CEL-197972 DHF is reduced to tetrahydrofolate (THF) IEA Caenorhabditis elegans 57453 R-CEL-200680 https://reactome.org/PathwayBrowser/#/R-CEL-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Caenorhabditis elegans 57453 R-CEL-200720 https://reactome.org/PathwayBrowser/#/R-CEL-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Caenorhabditis elegans 57453 R-CEL-3149539 https://reactome.org/PathwayBrowser/#/R-CEL-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Caenorhabditis elegans 57453 R-CEL-73605 https://reactome.org/PathwayBrowser/#/R-CEL-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Caenorhabditis elegans 57453 R-CEL-73798 https://reactome.org/PathwayBrowser/#/R-CEL-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Caenorhabditis elegans 57453 R-CEL-73813 https://reactome.org/PathwayBrowser/#/R-CEL-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Caenorhabditis elegans 57453 R-CFA-197958 https://reactome.org/PathwayBrowser/#/R-CFA-197958 FPGS-2 transforms THF to THFPG IEA Canis familiaris 57453 R-CFA-197972 https://reactome.org/PathwayBrowser/#/R-CFA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Canis familiaris 57453 R-CFA-200680 https://reactome.org/PathwayBrowser/#/R-CFA-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Canis familiaris 57453 R-CFA-200720 https://reactome.org/PathwayBrowser/#/R-CFA-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Canis familiaris 57453 R-CFA-3149539 https://reactome.org/PathwayBrowser/#/R-CFA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Canis familiaris 57453 R-CFA-70920 https://reactome.org/PathwayBrowser/#/R-CFA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Canis familiaris 57453 R-CFA-73605 https://reactome.org/PathwayBrowser/#/R-CFA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Canis familiaris 57453 R-CFA-73798 https://reactome.org/PathwayBrowser/#/R-CFA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Canis familiaris 57453 R-CFA-73813 https://reactome.org/PathwayBrowser/#/R-CFA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Canis familiaris 57453 R-DDI-197958 https://reactome.org/PathwayBrowser/#/R-DDI-197958 FPGS-2 transforms THF to THFPG IEA Dictyostelium discoideum 57453 R-DDI-197972 https://reactome.org/PathwayBrowser/#/R-DDI-197972 DHF is reduced to tetrahydrofolate (THF) IEA Dictyostelium discoideum 57453 R-DDI-200680 https://reactome.org/PathwayBrowser/#/R-DDI-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Dictyostelium discoideum 57453 R-DDI-200720 https://reactome.org/PathwayBrowser/#/R-DDI-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Dictyostelium discoideum 57453 R-DDI-3149539 https://reactome.org/PathwayBrowser/#/R-DDI-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Dictyostelium discoideum 57453 R-DDI-70920 https://reactome.org/PathwayBrowser/#/R-DDI-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Dictyostelium discoideum 57453 R-DDI-73798 https://reactome.org/PathwayBrowser/#/R-DDI-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Dictyostelium discoideum 57453 R-DDI-73813 https://reactome.org/PathwayBrowser/#/R-DDI-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Dictyostelium discoideum 57453 R-DME-197958 https://reactome.org/PathwayBrowser/#/R-DME-197958 FPGS-2 transforms THF to THFPG IEA Drosophila melanogaster 57453 R-DME-197972 https://reactome.org/PathwayBrowser/#/R-DME-197972 DHF is reduced to tetrahydrofolate (THF) IEA Drosophila melanogaster 57453 R-DME-200680 https://reactome.org/PathwayBrowser/#/R-DME-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Drosophila melanogaster 57453 R-DME-200720 https://reactome.org/PathwayBrowser/#/R-DME-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Drosophila melanogaster 57453 R-DME-73605 https://reactome.org/PathwayBrowser/#/R-DME-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Drosophila melanogaster 57453 R-DME-73798 https://reactome.org/PathwayBrowser/#/R-DME-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Drosophila melanogaster 57453 R-DME-73813 https://reactome.org/PathwayBrowser/#/R-DME-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Drosophila melanogaster 57453 R-DRE-197958 https://reactome.org/PathwayBrowser/#/R-DRE-197958 FPGS-2 transforms THF to THFPG IEA Danio rerio 57453 R-DRE-197972 https://reactome.org/PathwayBrowser/#/R-DRE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Danio rerio 57453 R-DRE-200680 https://reactome.org/PathwayBrowser/#/R-DRE-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Danio rerio 57453 R-DRE-200720 https://reactome.org/PathwayBrowser/#/R-DRE-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Danio rerio 57453 R-DRE-73605 https://reactome.org/PathwayBrowser/#/R-DRE-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Danio rerio 57453 R-DRE-73798 https://reactome.org/PathwayBrowser/#/R-DRE-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Danio rerio 57453 R-DRE-73813 https://reactome.org/PathwayBrowser/#/R-DRE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Danio rerio 57453 R-GGA-197958 https://reactome.org/PathwayBrowser/#/R-GGA-197958 FPGS-2 transforms THF to THFPG IEA Gallus gallus 57453 R-GGA-197972 https://reactome.org/PathwayBrowser/#/R-GGA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Gallus gallus 57453 R-GGA-200680 https://reactome.org/PathwayBrowser/#/R-GGA-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Gallus gallus 57453 R-GGA-200720 https://reactome.org/PathwayBrowser/#/R-GGA-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Gallus gallus 57453 R-GGA-3149539 https://reactome.org/PathwayBrowser/#/R-GGA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Gallus gallus 57453 R-GGA-419145 https://reactome.org/PathwayBrowser/#/R-GGA-419145 5-phosphoribosylglycinamide (GAR) + 10-formyl-tetrahydrofolate => 5'-phosphoribosylformylglycinamide (FGAR) + tetrahydrofolate TAS Gallus gallus 57453 R-GGA-419254 https://reactome.org/PathwayBrowser/#/R-GGA-419254 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + 10-formyltetrahydrofolate => 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) + tetrahydrofolate TAS Gallus gallus 57453 R-GGA-70920 https://reactome.org/PathwayBrowser/#/R-GGA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Gallus gallus 57453 R-GGA-73798 https://reactome.org/PathwayBrowser/#/R-GGA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Gallus gallus 57453 R-GGA-73813 https://reactome.org/PathwayBrowser/#/R-GGA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Gallus gallus 57453 R-HSA-197958 https://reactome.org/PathwayBrowser/#/R-HSA-197958 FPGS-2 transforms THF to THFPG TAS Homo sapiens 57453 R-HSA-197972 https://reactome.org/PathwayBrowser/#/R-HSA-197972 DHF is reduced to tetrahydrofolate (THF) TAS Homo sapiens 57453 R-HSA-200680 https://reactome.org/PathwayBrowser/#/R-HSA-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix TAS Homo sapiens 57453 R-HSA-200720 https://reactome.org/PathwayBrowser/#/R-HSA-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol TAS Homo sapiens 57453 R-HSA-3149539 https://reactome.org/PathwayBrowser/#/R-HSA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin TAS Homo sapiens 57453 R-HSA-70920 https://reactome.org/PathwayBrowser/#/R-HSA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate TAS Homo sapiens 57453 R-HSA-73605 https://reactome.org/PathwayBrowser/#/R-HSA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate TAS Homo sapiens 57453 R-HSA-73798 https://reactome.org/PathwayBrowser/#/R-HSA-73798 AICAR + 10-Formyl-THF => FAICAR + THF TAS Homo sapiens 57453 R-HSA-73813 https://reactome.org/PathwayBrowser/#/R-HSA-73813 GAR + 10-Formyl-THF => FGAR + THF TAS Homo sapiens 57453 R-MMU-197958 https://reactome.org/PathwayBrowser/#/R-MMU-197958 FPGS-2 transforms THF to THFPG IEA Mus musculus 57453 R-MMU-197972 https://reactome.org/PathwayBrowser/#/R-MMU-197972 DHF is reduced to tetrahydrofolate (THF) IEA Mus musculus 57453 R-MMU-200680 https://reactome.org/PathwayBrowser/#/R-MMU-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Mus musculus 57453 R-MMU-200720 https://reactome.org/PathwayBrowser/#/R-MMU-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Mus musculus 57453 R-MMU-3149539 https://reactome.org/PathwayBrowser/#/R-MMU-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Mus musculus 57453 R-MMU-70920 https://reactome.org/PathwayBrowser/#/R-MMU-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Mus musculus 57453 R-MMU-73605 https://reactome.org/PathwayBrowser/#/R-MMU-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Mus musculus 57453 R-MMU-73798 https://reactome.org/PathwayBrowser/#/R-MMU-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Mus musculus 57453 R-MMU-73813 https://reactome.org/PathwayBrowser/#/R-MMU-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Mus musculus 57453 R-PFA-200680 https://reactome.org/PathwayBrowser/#/R-PFA-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Plasmodium falciparum 57453 R-PFA-200720 https://reactome.org/PathwayBrowser/#/R-PFA-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Plasmodium falciparum 57453 R-PFA-73605 https://reactome.org/PathwayBrowser/#/R-PFA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Plasmodium falciparum 57453 R-RNO-197958 https://reactome.org/PathwayBrowser/#/R-RNO-197958 FPGS-2 transforms THF to THFPG IEA Rattus norvegicus 57453 R-RNO-197972 https://reactome.org/PathwayBrowser/#/R-RNO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Rattus norvegicus 57453 R-RNO-200680 https://reactome.org/PathwayBrowser/#/R-RNO-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Rattus norvegicus 57453 R-RNO-200720 https://reactome.org/PathwayBrowser/#/R-RNO-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Rattus norvegicus 57453 R-RNO-3149539 https://reactome.org/PathwayBrowser/#/R-RNO-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Rattus norvegicus 57453 R-RNO-70920 https://reactome.org/PathwayBrowser/#/R-RNO-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Rattus norvegicus 57453 R-RNO-73605 https://reactome.org/PathwayBrowser/#/R-RNO-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Rattus norvegicus 57453 R-RNO-73798 https://reactome.org/PathwayBrowser/#/R-RNO-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Rattus norvegicus 57453 R-RNO-73813 https://reactome.org/PathwayBrowser/#/R-RNO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Rattus norvegicus 57453 R-SCE-197958 https://reactome.org/PathwayBrowser/#/R-SCE-197958 FPGS-2 transforms THF to THFPG IEA Saccharomyces cerevisiae 57453 R-SCE-197972 https://reactome.org/PathwayBrowser/#/R-SCE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Saccharomyces cerevisiae 57453 R-SCE-200680 https://reactome.org/PathwayBrowser/#/R-SCE-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Saccharomyces cerevisiae 57453 R-SCE-200720 https://reactome.org/PathwayBrowser/#/R-SCE-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Saccharomyces cerevisiae 57453 R-SCE-73605 https://reactome.org/PathwayBrowser/#/R-SCE-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Saccharomyces cerevisiae 57453 R-SCE-73798 https://reactome.org/PathwayBrowser/#/R-SCE-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Saccharomyces cerevisiae 57453 R-SCE-73813 https://reactome.org/PathwayBrowser/#/R-SCE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Saccharomyces cerevisiae 57453 R-SPO-197958 https://reactome.org/PathwayBrowser/#/R-SPO-197958 FPGS-2 transforms THF to THFPG IEA Schizosaccharomyces pombe 57453 R-SPO-197972 https://reactome.org/PathwayBrowser/#/R-SPO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Schizosaccharomyces pombe 57453 R-SPO-200680 https://reactome.org/PathwayBrowser/#/R-SPO-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Schizosaccharomyces pombe 57453 R-SPO-200720 https://reactome.org/PathwayBrowser/#/R-SPO-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Schizosaccharomyces pombe 57453 R-SPO-73605 https://reactome.org/PathwayBrowser/#/R-SPO-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Schizosaccharomyces pombe 57453 R-SPO-73798 https://reactome.org/PathwayBrowser/#/R-SPO-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Schizosaccharomyces pombe 57453 R-SPO-73813 https://reactome.org/PathwayBrowser/#/R-SPO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Schizosaccharomyces pombe 57453 R-SSC-197958 https://reactome.org/PathwayBrowser/#/R-SSC-197958 FPGS-2 transforms THF to THFPG IEA Sus scrofa 57453 R-SSC-197972 https://reactome.org/PathwayBrowser/#/R-SSC-197972 DHF is reduced to tetrahydrofolate (THF) IEA Sus scrofa 57453 R-SSC-200680 https://reactome.org/PathwayBrowser/#/R-SSC-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Sus scrofa 57453 R-SSC-200720 https://reactome.org/PathwayBrowser/#/R-SSC-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Sus scrofa 57453 R-SSC-3149539 https://reactome.org/PathwayBrowser/#/R-SSC-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Sus scrofa 57453 R-SSC-70920 https://reactome.org/PathwayBrowser/#/R-SSC-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Sus scrofa 57453 R-SSC-73605 https://reactome.org/PathwayBrowser/#/R-SSC-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Sus scrofa 57453 R-SSC-73798 https://reactome.org/PathwayBrowser/#/R-SSC-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Sus scrofa 57453 R-SSC-73813 https://reactome.org/PathwayBrowser/#/R-SSC-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Sus scrofa 57453 R-XTR-197958 https://reactome.org/PathwayBrowser/#/R-XTR-197958 FPGS-2 transforms THF to THFPG IEA Xenopus tropicalis 57453 R-XTR-200680 https://reactome.org/PathwayBrowser/#/R-XTR-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Xenopus tropicalis 57453 R-XTR-200720 https://reactome.org/PathwayBrowser/#/R-XTR-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Xenopus tropicalis 57453 R-XTR-70920 https://reactome.org/PathwayBrowser/#/R-XTR-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate IEA Xenopus tropicalis 57453 R-XTR-73605 https://reactome.org/PathwayBrowser/#/R-XTR-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Xenopus tropicalis 57453 R-XTR-73813 https://reactome.org/PathwayBrowser/#/R-XTR-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Xenopus tropicalis 57454 R-BTA-5432520 https://reactome.org/PathwayBrowser/#/R-BTA-5432520 MTFMT formylates methionyl-tRNA TAS Bos taurus 57454 R-BTA-5696839 https://reactome.org/PathwayBrowser/#/R-BTA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Bos taurus 57454 R-BTA-6801456 https://reactome.org/PathwayBrowser/#/R-BTA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Bos taurus 57454 R-BTA-6801462 https://reactome.org/PathwayBrowser/#/R-BTA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Bos taurus 57454 R-BTA-73798 https://reactome.org/PathwayBrowser/#/R-BTA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Bos taurus 57454 R-BTA-73813 https://reactome.org/PathwayBrowser/#/R-BTA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Bos taurus 57454 R-CEL-5696839 https://reactome.org/PathwayBrowser/#/R-CEL-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Caenorhabditis elegans 57454 R-CEL-6801456 https://reactome.org/PathwayBrowser/#/R-CEL-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Caenorhabditis elegans 57454 R-CEL-73798 https://reactome.org/PathwayBrowser/#/R-CEL-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Caenorhabditis elegans 57454 R-CEL-73813 https://reactome.org/PathwayBrowser/#/R-CEL-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Caenorhabditis elegans 57454 R-CFA-5696839 https://reactome.org/PathwayBrowser/#/R-CFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Canis familiaris 57454 R-CFA-6801456 https://reactome.org/PathwayBrowser/#/R-CFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Canis familiaris 57454 R-CFA-6801462 https://reactome.org/PathwayBrowser/#/R-CFA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Canis familiaris 57454 R-CFA-73798 https://reactome.org/PathwayBrowser/#/R-CFA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Canis familiaris 57454 R-CFA-73813 https://reactome.org/PathwayBrowser/#/R-CFA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Canis familiaris 57454 R-DDI-5696839 https://reactome.org/PathwayBrowser/#/R-DDI-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Dictyostelium discoideum 57454 R-DDI-6801456 https://reactome.org/PathwayBrowser/#/R-DDI-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Dictyostelium discoideum 57454 R-DDI-6801462 https://reactome.org/PathwayBrowser/#/R-DDI-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Dictyostelium discoideum 57454 R-DDI-73798 https://reactome.org/PathwayBrowser/#/R-DDI-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Dictyostelium discoideum 57454 R-DDI-73813 https://reactome.org/PathwayBrowser/#/R-DDI-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Dictyostelium discoideum 57454 R-DME-5696839 https://reactome.org/PathwayBrowser/#/R-DME-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Drosophila melanogaster 57454 R-DME-6801456 https://reactome.org/PathwayBrowser/#/R-DME-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Drosophila melanogaster 57454 R-DME-6801462 https://reactome.org/PathwayBrowser/#/R-DME-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Drosophila melanogaster 57454 R-DME-73798 https://reactome.org/PathwayBrowser/#/R-DME-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Drosophila melanogaster 57454 R-DME-73813 https://reactome.org/PathwayBrowser/#/R-DME-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Drosophila melanogaster 57454 R-DRE-5696839 https://reactome.org/PathwayBrowser/#/R-DRE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Danio rerio 57454 R-DRE-6801456 https://reactome.org/PathwayBrowser/#/R-DRE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Danio rerio 57454 R-DRE-6801462 https://reactome.org/PathwayBrowser/#/R-DRE-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Danio rerio 57454 R-DRE-73798 https://reactome.org/PathwayBrowser/#/R-DRE-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Danio rerio 57454 R-DRE-73813 https://reactome.org/PathwayBrowser/#/R-DRE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Danio rerio 57454 R-GGA-419145 https://reactome.org/PathwayBrowser/#/R-GGA-419145 5-phosphoribosylglycinamide (GAR) + 10-formyl-tetrahydrofolate => 5'-phosphoribosylformylglycinamide (FGAR) + tetrahydrofolate TAS Gallus gallus 57454 R-GGA-419254 https://reactome.org/PathwayBrowser/#/R-GGA-419254 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + 10-formyltetrahydrofolate => 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) + tetrahydrofolate TAS Gallus gallus 57454 R-GGA-5696839 https://reactome.org/PathwayBrowser/#/R-GGA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Gallus gallus 57454 R-GGA-6801456 https://reactome.org/PathwayBrowser/#/R-GGA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Gallus gallus 57454 R-GGA-6801462 https://reactome.org/PathwayBrowser/#/R-GGA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Gallus gallus 57454 R-GGA-73798 https://reactome.org/PathwayBrowser/#/R-GGA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Gallus gallus 57454 R-GGA-73813 https://reactome.org/PathwayBrowser/#/R-GGA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Gallus gallus 57454 R-HSA-5389841 https://reactome.org/PathwayBrowser/#/R-HSA-5389841 MTFMT formylates methionyl-tRNA IEA Homo sapiens 57454 R-HSA-5696839 https://reactome.org/PathwayBrowser/#/R-HSA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF TAS Homo sapiens 57454 R-HSA-6801456 https://reactome.org/PathwayBrowser/#/R-HSA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF TAS Homo sapiens 57454 R-HSA-6801462 https://reactome.org/PathwayBrowser/#/R-HSA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF TAS Homo sapiens 57454 R-HSA-73798 https://reactome.org/PathwayBrowser/#/R-HSA-73798 AICAR + 10-Formyl-THF => FAICAR + THF TAS Homo sapiens 57454 R-HSA-73813 https://reactome.org/PathwayBrowser/#/R-HSA-73813 GAR + 10-Formyl-THF => FGAR + THF TAS Homo sapiens 57454 R-MMU-5696839 https://reactome.org/PathwayBrowser/#/R-MMU-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Mus musculus 57454 R-MMU-6801456 https://reactome.org/PathwayBrowser/#/R-MMU-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Mus musculus 57454 R-MMU-6801462 https://reactome.org/PathwayBrowser/#/R-MMU-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Mus musculus 57454 R-MMU-73798 https://reactome.org/PathwayBrowser/#/R-MMU-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Mus musculus 57454 R-MMU-73813 https://reactome.org/PathwayBrowser/#/R-MMU-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Mus musculus 57454 R-PFA-5696839 https://reactome.org/PathwayBrowser/#/R-PFA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Plasmodium falciparum 57454 R-PFA-6801456 https://reactome.org/PathwayBrowser/#/R-PFA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Plasmodium falciparum 57454 R-PFA-6801462 https://reactome.org/PathwayBrowser/#/R-PFA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Plasmodium falciparum 57454 R-RNO-5696839 https://reactome.org/PathwayBrowser/#/R-RNO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Rattus norvegicus 57454 R-RNO-6801456 https://reactome.org/PathwayBrowser/#/R-RNO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Rattus norvegicus 57454 R-RNO-6801462 https://reactome.org/PathwayBrowser/#/R-RNO-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Rattus norvegicus 57454 R-RNO-73798 https://reactome.org/PathwayBrowser/#/R-RNO-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Rattus norvegicus 57454 R-RNO-73813 https://reactome.org/PathwayBrowser/#/R-RNO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Rattus norvegicus 57454 R-SCE-5696839 https://reactome.org/PathwayBrowser/#/R-SCE-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Saccharomyces cerevisiae 57454 R-SCE-6801456 https://reactome.org/PathwayBrowser/#/R-SCE-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Saccharomyces cerevisiae 57454 R-SCE-6801462 https://reactome.org/PathwayBrowser/#/R-SCE-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Saccharomyces cerevisiae 57454 R-SCE-73798 https://reactome.org/PathwayBrowser/#/R-SCE-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Saccharomyces cerevisiae 57454 R-SCE-73813 https://reactome.org/PathwayBrowser/#/R-SCE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Saccharomyces cerevisiae 57454 R-SPO-5696839 https://reactome.org/PathwayBrowser/#/R-SPO-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Schizosaccharomyces pombe 57454 R-SPO-6801456 https://reactome.org/PathwayBrowser/#/R-SPO-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Schizosaccharomyces pombe 57454 R-SPO-6801462 https://reactome.org/PathwayBrowser/#/R-SPO-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Schizosaccharomyces pombe 57454 R-SPO-73798 https://reactome.org/PathwayBrowser/#/R-SPO-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Schizosaccharomyces pombe 57454 R-SPO-73813 https://reactome.org/PathwayBrowser/#/R-SPO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Schizosaccharomyces pombe 57454 R-SSC-5696839 https://reactome.org/PathwayBrowser/#/R-SSC-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Sus scrofa 57454 R-SSC-6801456 https://reactome.org/PathwayBrowser/#/R-SSC-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Sus scrofa 57454 R-SSC-6801462 https://reactome.org/PathwayBrowser/#/R-SSC-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Sus scrofa 57454 R-SSC-73798 https://reactome.org/PathwayBrowser/#/R-SSC-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Sus scrofa 57454 R-SSC-73813 https://reactome.org/PathwayBrowser/#/R-SSC-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Sus scrofa 57454 R-XTR-5696839 https://reactome.org/PathwayBrowser/#/R-XTR-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Xenopus tropicalis 57454 R-XTR-6801456 https://reactome.org/PathwayBrowser/#/R-XTR-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Xenopus tropicalis 57454 R-XTR-6801462 https://reactome.org/PathwayBrowser/#/R-XTR-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Xenopus tropicalis 57454 R-XTR-73813 https://reactome.org/PathwayBrowser/#/R-XTR-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Xenopus tropicalis 57455 R-BTA-6801328 https://reactome.org/PathwayBrowser/#/R-BTA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Bos taurus 57455 R-BTA-6801462 https://reactome.org/PathwayBrowser/#/R-BTA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Bos taurus 57455 R-CFA-6801328 https://reactome.org/PathwayBrowser/#/R-CFA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Canis familiaris 57455 R-CFA-6801462 https://reactome.org/PathwayBrowser/#/R-CFA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Canis familiaris 57455 R-DDI-6801328 https://reactome.org/PathwayBrowser/#/R-DDI-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Dictyostelium discoideum 57455 R-DDI-6801462 https://reactome.org/PathwayBrowser/#/R-DDI-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Dictyostelium discoideum 57455 R-DME-6801328 https://reactome.org/PathwayBrowser/#/R-DME-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Drosophila melanogaster 57455 R-DME-6801462 https://reactome.org/PathwayBrowser/#/R-DME-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Drosophila melanogaster 57455 R-DRE-6801328 https://reactome.org/PathwayBrowser/#/R-DRE-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Danio rerio 57455 R-DRE-6801462 https://reactome.org/PathwayBrowser/#/R-DRE-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Danio rerio 57455 R-GGA-6801328 https://reactome.org/PathwayBrowser/#/R-GGA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Gallus gallus 57455 R-GGA-6801462 https://reactome.org/PathwayBrowser/#/R-GGA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Gallus gallus 57455 R-HSA-6801328 https://reactome.org/PathwayBrowser/#/R-HSA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF TAS Homo sapiens 57455 R-HSA-6801462 https://reactome.org/PathwayBrowser/#/R-HSA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF TAS Homo sapiens 57455 R-MMU-6801328 https://reactome.org/PathwayBrowser/#/R-MMU-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Mus musculus 57455 R-MMU-6801462 https://reactome.org/PathwayBrowser/#/R-MMU-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Mus musculus 57455 R-PFA-6801328 https://reactome.org/PathwayBrowser/#/R-PFA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Plasmodium falciparum 57455 R-PFA-6801462 https://reactome.org/PathwayBrowser/#/R-PFA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Plasmodium falciparum 57455 R-RNO-6801328 https://reactome.org/PathwayBrowser/#/R-RNO-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Rattus norvegicus 57455 R-RNO-6801462 https://reactome.org/PathwayBrowser/#/R-RNO-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Rattus norvegicus 57455 R-SCE-6801328 https://reactome.org/PathwayBrowser/#/R-SCE-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Saccharomyces cerevisiae 57455 R-SCE-6801462 https://reactome.org/PathwayBrowser/#/R-SCE-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Saccharomyces cerevisiae 57455 R-SPO-6801328 https://reactome.org/PathwayBrowser/#/R-SPO-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Schizosaccharomyces pombe 57455 R-SPO-6801462 https://reactome.org/PathwayBrowser/#/R-SPO-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Schizosaccharomyces pombe 57455 R-SSC-6801328 https://reactome.org/PathwayBrowser/#/R-SSC-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Sus scrofa 57455 R-SSC-6801462 https://reactome.org/PathwayBrowser/#/R-SSC-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Sus scrofa 57455 R-XTR-6801328 https://reactome.org/PathwayBrowser/#/R-XTR-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Xenopus tropicalis 57455 R-XTR-6801462 https://reactome.org/PathwayBrowser/#/R-XTR-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Xenopus tropicalis 57464 R-BTA-2509831 https://reactome.org/PathwayBrowser/#/R-BTA-2509831 ITPA hydrolyses XTP to XMP IEA Bos taurus 57464 R-BTA-73792 https://reactome.org/PathwayBrowser/#/R-BTA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Bos taurus 57464 R-BTA-73794 https://reactome.org/PathwayBrowser/#/R-BTA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Bos taurus 57464 R-CEL-2509831 https://reactome.org/PathwayBrowser/#/R-CEL-2509831 ITPA hydrolyses XTP to XMP IEA Caenorhabditis elegans 57464 R-CEL-73792 https://reactome.org/PathwayBrowser/#/R-CEL-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Caenorhabditis elegans 57464 R-CEL-73794 https://reactome.org/PathwayBrowser/#/R-CEL-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Caenorhabditis elegans 57464 R-CFA-2509831 https://reactome.org/PathwayBrowser/#/R-CFA-2509831 ITPA hydrolyses XTP to XMP IEA Canis familiaris 57464 R-CFA-73792 https://reactome.org/PathwayBrowser/#/R-CFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Canis familiaris 57464 R-CFA-73794 https://reactome.org/PathwayBrowser/#/R-CFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Canis familiaris 57464 R-DDI-2509831 https://reactome.org/PathwayBrowser/#/R-DDI-2509831 ITPA hydrolyses XTP to XMP IEA Dictyostelium discoideum 57464 R-DDI-73792 https://reactome.org/PathwayBrowser/#/R-DDI-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Dictyostelium discoideum 57464 R-DDI-73794 https://reactome.org/PathwayBrowser/#/R-DDI-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Dictyostelium discoideum 57464 R-DME-2509831 https://reactome.org/PathwayBrowser/#/R-DME-2509831 ITPA hydrolyses XTP to XMP IEA Drosophila melanogaster 57464 R-DME-73792 https://reactome.org/PathwayBrowser/#/R-DME-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Drosophila melanogaster 57464 R-DME-73794 https://reactome.org/PathwayBrowser/#/R-DME-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Drosophila melanogaster 57464 R-DRE-2509831 https://reactome.org/PathwayBrowser/#/R-DRE-2509831 ITPA hydrolyses XTP to XMP IEA Danio rerio 57464 R-DRE-73794 https://reactome.org/PathwayBrowser/#/R-DRE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Danio rerio 57464 R-GGA-2509831 https://reactome.org/PathwayBrowser/#/R-GGA-2509831 ITPA hydrolyses XTP to XMP IEA Gallus gallus 57464 R-GGA-421218 https://reactome.org/PathwayBrowser/#/R-GGA-421218 xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate IEA Gallus gallus 57464 R-GGA-421222 https://reactome.org/PathwayBrowser/#/R-GGA-421222 inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ IEA Gallus gallus 57464 R-GGA-73792 https://reactome.org/PathwayBrowser/#/R-GGA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Gallus gallus 57464 R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus 57464 R-HSA-2509831 https://reactome.org/PathwayBrowser/#/R-HSA-2509831 ITPA hydrolyses XTP to XMP TAS Homo sapiens 57464 R-HSA-73792 https://reactome.org/PathwayBrowser/#/R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate TAS Homo sapiens 57464 R-HSA-73794 https://reactome.org/PathwayBrowser/#/R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] TAS Homo sapiens 57464 R-MMU-2509831 https://reactome.org/PathwayBrowser/#/R-MMU-2509831 ITPA hydrolyses XTP to XMP IEA Mus musculus 57464 R-MMU-73792 https://reactome.org/PathwayBrowser/#/R-MMU-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Mus musculus 57464 R-MMU-73794 https://reactome.org/PathwayBrowser/#/R-MMU-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Mus musculus 57464 R-PFA-2509831 https://reactome.org/PathwayBrowser/#/R-PFA-2509831 ITPA hydrolyses XTP to XMP IEA Plasmodium falciparum 57464 R-PFA-73792 https://reactome.org/PathwayBrowser/#/R-PFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Plasmodium falciparum 57464 R-PFA-73794 https://reactome.org/PathwayBrowser/#/R-PFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Plasmodium falciparum 57464 R-RNO-2509831 https://reactome.org/PathwayBrowser/#/R-RNO-2509831 ITPA hydrolyses XTP to XMP IEA Rattus norvegicus 57464 R-RNO-73792 https://reactome.org/PathwayBrowser/#/R-RNO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Rattus norvegicus 57464 R-RNO-73794 https://reactome.org/PathwayBrowser/#/R-RNO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Rattus norvegicus 57464 R-SCE-2509831 https://reactome.org/PathwayBrowser/#/R-SCE-2509831 ITPA hydrolyses XTP to XMP IEA Saccharomyces cerevisiae 57464 R-SCE-73792 https://reactome.org/PathwayBrowser/#/R-SCE-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Saccharomyces cerevisiae 57464 R-SCE-73794 https://reactome.org/PathwayBrowser/#/R-SCE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Saccharomyces cerevisiae 57464 R-SPO-2509831 https://reactome.org/PathwayBrowser/#/R-SPO-2509831 ITPA hydrolyses XTP to XMP IEA Schizosaccharomyces pombe 57464 R-SPO-73792 https://reactome.org/PathwayBrowser/#/R-SPO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Schizosaccharomyces pombe 57464 R-SPO-73794 https://reactome.org/PathwayBrowser/#/R-SPO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Schizosaccharomyces pombe 57464 R-SSC-2509831 https://reactome.org/PathwayBrowser/#/R-SSC-2509831 ITPA hydrolyses XTP to XMP IEA Sus scrofa 57464 R-SSC-73792 https://reactome.org/PathwayBrowser/#/R-SSC-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Sus scrofa 57464 R-SSC-73794 https://reactome.org/PathwayBrowser/#/R-SSC-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Sus scrofa 57464 R-XTR-2509831 https://reactome.org/PathwayBrowser/#/R-XTR-2509831 ITPA hydrolyses XTP to XMP IEA Xenopus tropicalis 57464 R-XTR-73792 https://reactome.org/PathwayBrowser/#/R-XTR-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Xenopus tropicalis 57464 R-XTR-73794 https://reactome.org/PathwayBrowser/#/R-XTR-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Xenopus tropicalis 57472 R-BTA-70573 https://reactome.org/PathwayBrowser/#/R-BTA-70573 argininosuccinate <=> fumarate + arginine IEA Bos taurus 57472 R-BTA-70577 https://reactome.org/PathwayBrowser/#/R-BTA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Bos taurus 57472 R-CFA-70573 https://reactome.org/PathwayBrowser/#/R-CFA-70573 argininosuccinate <=> fumarate + arginine IEA Canis familiaris 57472 R-CFA-70577 https://reactome.org/PathwayBrowser/#/R-CFA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Canis familiaris 57472 R-DME-70573 https://reactome.org/PathwayBrowser/#/R-DME-70573 argininosuccinate <=> fumarate + arginine IEA Drosophila melanogaster 57472 R-DRE-70573 https://reactome.org/PathwayBrowser/#/R-DRE-70573 argininosuccinate <=> fumarate + arginine IEA Danio rerio 57472 R-GGA-187586 https://reactome.org/PathwayBrowser/#/R-GGA-187586 ATP + aspartate + citrulline <=> argininosuccinate + AMP + pyrophosphate TAS Gallus gallus 57472 R-GGA-187617 https://reactome.org/PathwayBrowser/#/R-GGA-187617 argininosuccinate <=> fumarate + arginine TAS Gallus gallus 57472 R-GGA-70573 https://reactome.org/PathwayBrowser/#/R-GGA-70573 argininosuccinate <=> fumarate + arginine IEA Gallus gallus 57472 R-GGA-70577 https://reactome.org/PathwayBrowser/#/R-GGA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Gallus gallus 57472 R-HSA-70573 https://reactome.org/PathwayBrowser/#/R-HSA-70573 argininosuccinate <=> fumarate + arginine TAS Homo sapiens 57472 R-HSA-70577 https://reactome.org/PathwayBrowser/#/R-HSA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA TAS Homo sapiens 57472 R-MMU-70573 https://reactome.org/PathwayBrowser/#/R-MMU-70573 argininosuccinate <=> fumarate + arginine IEA Mus musculus 57472 R-MMU-70577 https://reactome.org/PathwayBrowser/#/R-MMU-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Mus musculus 57472 R-RNO-70573 https://reactome.org/PathwayBrowser/#/R-RNO-70573 argininosuccinate <=> fumarate + arginine IEA Rattus norvegicus 57472 R-SCE-70573 https://reactome.org/PathwayBrowser/#/R-SCE-70573 argininosuccinate <=> fumarate + arginine IEA Saccharomyces cerevisiae 57472 R-SPO-70573 https://reactome.org/PathwayBrowser/#/R-SPO-70573 argininosuccinate <=> fumarate + arginine IEA Schizosaccharomyces pombe 57472 R-SSC-70573 https://reactome.org/PathwayBrowser/#/R-SSC-70573 argininosuccinate <=> fumarate + arginine IEA Sus scrofa 57472 R-SSC-70577 https://reactome.org/PathwayBrowser/#/R-SSC-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Sus scrofa 57472 R-XTR-70573 https://reactome.org/PathwayBrowser/#/R-XTR-70573 argininosuccinate <=> fumarate + arginine IEA Xenopus tropicalis 57474 R-BTA-5694071 https://reactome.org/PathwayBrowser/#/R-BTA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Bos taurus 57474 R-BTA-6783221 https://reactome.org/PathwayBrowser/#/R-BTA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Bos taurus 57474 R-CEL-6783221 https://reactome.org/PathwayBrowser/#/R-CEL-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Caenorhabditis elegans 57474 R-CFA-5694071 https://reactome.org/PathwayBrowser/#/R-CFA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Canis familiaris 57474 R-CFA-6783221 https://reactome.org/PathwayBrowser/#/R-CFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Canis familiaris 57474 R-DDI-6783221 https://reactome.org/PathwayBrowser/#/R-DDI-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Dictyostelium discoideum 57474 R-DME-5694071 https://reactome.org/PathwayBrowser/#/R-DME-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Drosophila melanogaster 57474 R-DME-6783221 https://reactome.org/PathwayBrowser/#/R-DME-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Drosophila melanogaster 57474 R-DRE-5694071 https://reactome.org/PathwayBrowser/#/R-DRE-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Danio rerio 57474 R-DRE-6783221 https://reactome.org/PathwayBrowser/#/R-DRE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Danio rerio 57474 R-GGA-5694071 https://reactome.org/PathwayBrowser/#/R-GGA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Gallus gallus 57474 R-GGA-6783221 https://reactome.org/PathwayBrowser/#/R-GGA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Gallus gallus 57474 R-HSA-5694071 https://reactome.org/PathwayBrowser/#/R-HSA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH TAS Homo sapiens 57474 R-HSA-6783221 https://reactome.org/PathwayBrowser/#/R-HSA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT TAS Homo sapiens 57474 R-MMU-5694071 https://reactome.org/PathwayBrowser/#/R-MMU-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Mus musculus 57474 R-MMU-6783221 https://reactome.org/PathwayBrowser/#/R-MMU-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Mus musculus 57474 R-PFA-5694071 https://reactome.org/PathwayBrowser/#/R-PFA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Plasmodium falciparum 57474 R-PFA-6783221 https://reactome.org/PathwayBrowser/#/R-PFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Plasmodium falciparum 57474 R-RNO-5694071 https://reactome.org/PathwayBrowser/#/R-RNO-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Rattus norvegicus 57474 R-RNO-6783221 https://reactome.org/PathwayBrowser/#/R-RNO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Rattus norvegicus 57474 R-SCE-5694071 https://reactome.org/PathwayBrowser/#/R-SCE-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Saccharomyces cerevisiae 57474 R-SCE-6783221 https://reactome.org/PathwayBrowser/#/R-SCE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Saccharomyces cerevisiae 57474 R-SPO-5694071 https://reactome.org/PathwayBrowser/#/R-SPO-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Schizosaccharomyces pombe 57474 R-SPO-6783221 https://reactome.org/PathwayBrowser/#/R-SPO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Schizosaccharomyces pombe 57474 R-SSC-5694071 https://reactome.org/PathwayBrowser/#/R-SSC-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Sus scrofa 57474 R-SSC-6783221 https://reactome.org/PathwayBrowser/#/R-SSC-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Sus scrofa 57474 R-XTR-5694071 https://reactome.org/PathwayBrowser/#/R-XTR-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Xenopus tropicalis 57474 R-XTR-6783221 https://reactome.org/PathwayBrowser/#/R-XTR-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Xenopus tropicalis 57485 R-BTA-6786245 https://reactome.org/PathwayBrowser/#/R-BTA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Bos taurus 57485 R-BTA-8876789 https://reactome.org/PathwayBrowser/#/R-BTA-8876789 CARNMT1 methylates CARN to Anserine IEA Bos taurus 57485 R-CFA-6786245 https://reactome.org/PathwayBrowser/#/R-CFA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Canis familiaris 57485 R-CFA-8876789 https://reactome.org/PathwayBrowser/#/R-CFA-8876789 CARNMT1 methylates CARN to Anserine IEA Canis familiaris 57485 R-DDI-8876789 https://reactome.org/PathwayBrowser/#/R-DDI-8876789 CARNMT1 methylates CARN to Anserine IEA Dictyostelium discoideum 57485 R-DME-8876789 https://reactome.org/PathwayBrowser/#/R-DME-8876789 CARNMT1 methylates CARN to Anserine IEA Drosophila melanogaster 57485 R-GGA-6786245 https://reactome.org/PathwayBrowser/#/R-GGA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Gallus gallus 57485 R-GGA-8876789 https://reactome.org/PathwayBrowser/#/R-GGA-8876789 CARNMT1 methylates CARN to Anserine IEA Gallus gallus 57485 R-HSA-6786245 https://reactome.org/PathwayBrowser/#/R-HSA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN TAS Homo sapiens 57485 R-HSA-8876789 https://reactome.org/PathwayBrowser/#/R-HSA-8876789 CARNMT1 methylates CARN to Anserine TAS Homo sapiens 57485 R-MMU-6786245 https://reactome.org/PathwayBrowser/#/R-MMU-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Mus musculus 57485 R-MMU-8876789 https://reactome.org/PathwayBrowser/#/R-MMU-8876789 CARNMT1 methylates CARN to Anserine IEA Mus musculus 57485 R-PFA-8876789 https://reactome.org/PathwayBrowser/#/R-PFA-8876789 CARNMT1 methylates CARN to Anserine IEA Plasmodium falciparum 57485 R-RNO-6786245 https://reactome.org/PathwayBrowser/#/R-RNO-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Rattus norvegicus 57485 R-RNO-8876789 https://reactome.org/PathwayBrowser/#/R-RNO-8876789 CARNMT1 methylates CARN to Anserine IEA Rattus norvegicus 57485 R-SCE-8876789 https://reactome.org/PathwayBrowser/#/R-SCE-8876789 CARNMT1 methylates CARN to Anserine IEA Saccharomyces cerevisiae 57485 R-SPO-8876789 https://reactome.org/PathwayBrowser/#/R-SPO-8876789 CARNMT1 methylates CARN to Anserine IEA Schizosaccharomyces pombe 57485 R-SSC-6786245 https://reactome.org/PathwayBrowser/#/R-SSC-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Sus scrofa 57485 R-SSC-8876789 https://reactome.org/PathwayBrowser/#/R-SSC-8876789 CARNMT1 methylates CARN to Anserine IEA Sus scrofa 57485 R-XTR-6786245 https://reactome.org/PathwayBrowser/#/R-XTR-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Xenopus tropicalis 57499 R-BTA-372480 https://reactome.org/PathwayBrowser/#/R-BTA-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Bos taurus 57499 R-BTA-508561 https://reactome.org/PathwayBrowser/#/R-BTA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Bos taurus 57499 R-BTA-70952 https://reactome.org/PathwayBrowser/#/R-BTA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Bos taurus 57499 R-BTA-71037 https://reactome.org/PathwayBrowser/#/R-BTA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Bos taurus 57499 R-CEL-372480 https://reactome.org/PathwayBrowser/#/R-CEL-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Caenorhabditis elegans 57499 R-CEL-71037 https://reactome.org/PathwayBrowser/#/R-CEL-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 57499 R-CFA-372480 https://reactome.org/PathwayBrowser/#/R-CFA-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Canis familiaris 57499 R-CFA-508561 https://reactome.org/PathwayBrowser/#/R-CFA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Canis familiaris 57499 R-CFA-70952 https://reactome.org/PathwayBrowser/#/R-CFA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Canis familiaris 57499 R-CFA-71037 https://reactome.org/PathwayBrowser/#/R-CFA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Canis familiaris 57499 R-DDI-372480 https://reactome.org/PathwayBrowser/#/R-DDI-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Dictyostelium discoideum 57499 R-DDI-508561 https://reactome.org/PathwayBrowser/#/R-DDI-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Dictyostelium discoideum 57499 R-DDI-70952 https://reactome.org/PathwayBrowser/#/R-DDI-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Dictyostelium discoideum 57499 R-DDI-71037 https://reactome.org/PathwayBrowser/#/R-DDI-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 57499 R-DME-372480 https://reactome.org/PathwayBrowser/#/R-DME-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Drosophila melanogaster 57499 R-DME-71037 https://reactome.org/PathwayBrowser/#/R-DME-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 57499 R-DRE-372480 https://reactome.org/PathwayBrowser/#/R-DRE-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Danio rerio 57499 R-DRE-71037 https://reactome.org/PathwayBrowser/#/R-DRE-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Danio rerio 57499 R-GGA-372480 https://reactome.org/PathwayBrowser/#/R-GGA-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Gallus gallus 57499 R-GGA-372742 https://reactome.org/PathwayBrowser/#/R-GGA-372742 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Gallus gallus 57499 R-GGA-508561 https://reactome.org/PathwayBrowser/#/R-GGA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Gallus gallus 57499 R-GGA-70952 https://reactome.org/PathwayBrowser/#/R-GGA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Gallus gallus 57499 R-GGA-71037 https://reactome.org/PathwayBrowser/#/R-GGA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Gallus gallus 57499 R-HSA-372480 https://reactome.org/PathwayBrowser/#/R-HSA-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] TAS Homo sapiens 57499 R-HSA-508561 https://reactome.org/PathwayBrowser/#/R-HSA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate TAS Homo sapiens 57499 R-HSA-70952 https://reactome.org/PathwayBrowser/#/R-HSA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate TAS Homo sapiens 57499 R-HSA-71037 https://reactome.org/PathwayBrowser/#/R-HSA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ TAS Homo sapiens 57499 R-MMU-372480 https://reactome.org/PathwayBrowser/#/R-MMU-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Mus musculus 57499 R-MMU-508561 https://reactome.org/PathwayBrowser/#/R-MMU-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Mus musculus 57499 R-MMU-70952 https://reactome.org/PathwayBrowser/#/R-MMU-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Mus musculus 57499 R-MMU-71037 https://reactome.org/PathwayBrowser/#/R-MMU-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Mus musculus 57499 R-RNO-372480 https://reactome.org/PathwayBrowser/#/R-RNO-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Rattus norvegicus 57499 R-RNO-508561 https://reactome.org/PathwayBrowser/#/R-RNO-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Rattus norvegicus 57499 R-RNO-70952 https://reactome.org/PathwayBrowser/#/R-RNO-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Rattus norvegicus 57499 R-RNO-71037 https://reactome.org/PathwayBrowser/#/R-RNO-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 57499 R-SCE-508561 https://reactome.org/PathwayBrowser/#/R-SCE-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Saccharomyces cerevisiae 57499 R-SCE-70952 https://reactome.org/PathwayBrowser/#/R-SCE-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Saccharomyces cerevisiae 57499 R-SPO-508561 https://reactome.org/PathwayBrowser/#/R-SPO-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Schizosaccharomyces pombe 57499 R-SPO-70952 https://reactome.org/PathwayBrowser/#/R-SPO-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Schizosaccharomyces pombe 57499 R-SSC-372480 https://reactome.org/PathwayBrowser/#/R-SSC-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Sus scrofa 57499 R-SSC-508561 https://reactome.org/PathwayBrowser/#/R-SSC-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Sus scrofa 57499 R-SSC-70952 https://reactome.org/PathwayBrowser/#/R-SSC-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Sus scrofa 57499 R-SSC-71037 https://reactome.org/PathwayBrowser/#/R-SSC-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Sus scrofa 57499 R-XTR-372480 https://reactome.org/PathwayBrowser/#/R-XTR-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Xenopus tropicalis 57499 R-XTR-508561 https://reactome.org/PathwayBrowser/#/R-XTR-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Xenopus tropicalis 57499 R-XTR-70952 https://reactome.org/PathwayBrowser/#/R-XTR-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Xenopus tropicalis 57499 R-XTR-71037 https://reactome.org/PathwayBrowser/#/R-XTR-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 57504 R-BTA-209823 https://reactome.org/PathwayBrowser/#/R-BTA-209823 Tyrosine is hydroxylated to dopa IEA Bos taurus 57504 R-BTA-209924 https://reactome.org/PathwayBrowser/#/R-BTA-209924 Dopa is decarboxylated to dopamine IEA Bos taurus 57504 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 57504 R-BTA-5662692 https://reactome.org/PathwayBrowser/#/R-BTA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Bos taurus 57504 R-BTA-5663050 https://reactome.org/PathwayBrowser/#/R-BTA-5663050 DHI and DHICA polymerize forming eumelanin IEA Bos taurus 57504 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 57504 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 57504 R-BTA-8851298 https://reactome.org/PathwayBrowser/#/R-BTA-8851298 GPR143 binds L-Dopa IEA Bos taurus 57504 R-CEL-209823 https://reactome.org/PathwayBrowser/#/R-CEL-209823 Tyrosine is hydroxylated to dopa IEA Caenorhabditis elegans 57504 R-CEL-209924 https://reactome.org/PathwayBrowser/#/R-CEL-209924 Dopa is decarboxylated to dopamine IEA Caenorhabditis elegans 57504 R-CEL-5662692 https://reactome.org/PathwayBrowser/#/R-CEL-5662692 Dopa is oxidized to dopaquinone by TYR IEA Caenorhabditis elegans 57504 R-CEL-5663050 https://reactome.org/PathwayBrowser/#/R-CEL-5663050 DHI and DHICA polymerize forming eumelanin IEA Caenorhabditis elegans 57504 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 57504 R-CFA-209823 https://reactome.org/PathwayBrowser/#/R-CFA-209823 Tyrosine is hydroxylated to dopa IEA Canis familiaris 57504 R-CFA-209924 https://reactome.org/PathwayBrowser/#/R-CFA-209924 Dopa is decarboxylated to dopamine IEA Canis familiaris 57504 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 57504 R-CFA-5662692 https://reactome.org/PathwayBrowser/#/R-CFA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Canis familiaris 57504 R-CFA-5663050 https://reactome.org/PathwayBrowser/#/R-CFA-5663050 DHI and DHICA polymerize forming eumelanin IEA Canis familiaris 57504 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 57504 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 57504 R-CFA-8851298 https://reactome.org/PathwayBrowser/#/R-CFA-8851298 GPR143 binds L-Dopa IEA Canis familiaris 57504 R-DDI-209823 https://reactome.org/PathwayBrowser/#/R-DDI-209823 Tyrosine is hydroxylated to dopa IEA Dictyostelium discoideum 57504 R-DDI-5662692 https://reactome.org/PathwayBrowser/#/R-DDI-5662692 Dopa is oxidized to dopaquinone by TYR IEA Dictyostelium discoideum 57504 R-DDI-5663050 https://reactome.org/PathwayBrowser/#/R-DDI-5663050 DHI and DHICA polymerize forming eumelanin IEA Dictyostelium discoideum 57504 R-DME-209823 https://reactome.org/PathwayBrowser/#/R-DME-209823 Tyrosine is hydroxylated to dopa IEA Drosophila melanogaster 57504 R-DME-209924 https://reactome.org/PathwayBrowser/#/R-DME-209924 Dopa is decarboxylated to dopamine IEA Drosophila melanogaster 57504 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 57504 R-DRE-209823 https://reactome.org/PathwayBrowser/#/R-DRE-209823 Tyrosine is hydroxylated to dopa IEA Danio rerio 57504 R-DRE-209924 https://reactome.org/PathwayBrowser/#/R-DRE-209924 Dopa is decarboxylated to dopamine IEA Danio rerio 57504 R-GGA-209823 https://reactome.org/PathwayBrowser/#/R-GGA-209823 Tyrosine is hydroxylated to dopa IEA Gallus gallus 57504 R-GGA-209924 https://reactome.org/PathwayBrowser/#/R-GGA-209924 Dopa is decarboxylated to dopamine IEA Gallus gallus 57504 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 57504 R-GGA-5662692 https://reactome.org/PathwayBrowser/#/R-GGA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Gallus gallus 57504 R-GGA-5663050 https://reactome.org/PathwayBrowser/#/R-GGA-5663050 DHI and DHICA polymerize forming eumelanin IEA Gallus gallus 57504 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 57504 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 57504 R-GGA-8851298 https://reactome.org/PathwayBrowser/#/R-GGA-8851298 GPR143 binds L-Dopa IEA Gallus gallus 57504 R-HSA-209823 https://reactome.org/PathwayBrowser/#/R-HSA-209823 Tyrosine is hydroxylated to dopa TAS Homo sapiens 57504 R-HSA-209924 https://reactome.org/PathwayBrowser/#/R-HSA-209924 Dopa is decarboxylated to dopamine TAS Homo sapiens 57504 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 57504 R-HSA-5662692 https://reactome.org/PathwayBrowser/#/R-HSA-5662692 Dopa is oxidized to dopaquinone by TYR TAS Homo sapiens 57504 R-HSA-5662904 https://reactome.org/PathwayBrowser/#/R-HSA-5662904 CD isomers transform to BT, BTCA, BZ, ODHBT TAS Homo sapiens 57504 R-HSA-5663050 https://reactome.org/PathwayBrowser/#/R-HSA-5663050 DHI and DHICA polymerize forming eumelanin TAS Homo sapiens 57504 R-HSA-5672019 https://reactome.org/PathwayBrowser/#/R-HSA-5672019 Leucodopachrome, L-Dopaquinone transform to Dopachrome, L-Dopa TAS Homo sapiens 57504 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 57504 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 57504 R-HSA-8851298 https://reactome.org/PathwayBrowser/#/R-HSA-8851298 GPR143 binds L-Dopa TAS Homo sapiens 57504 R-MMU-209823 https://reactome.org/PathwayBrowser/#/R-MMU-209823 Tyrosine is hydroxylated to dopa IEA Mus musculus 57504 R-MMU-209924 https://reactome.org/PathwayBrowser/#/R-MMU-209924 Dopa is decarboxylated to dopamine IEA Mus musculus 57504 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 57504 R-MMU-5662692 https://reactome.org/PathwayBrowser/#/R-MMU-5662692 Dopa is oxidized to dopaquinone by TYR IEA Mus musculus 57504 R-MMU-5663050 https://reactome.org/PathwayBrowser/#/R-MMU-5663050 DHI and DHICA polymerize forming eumelanin IEA Mus musculus 57504 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 57504 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 57504 R-MMU-8851298 https://reactome.org/PathwayBrowser/#/R-MMU-8851298 GPR143 binds L-Dopa IEA Mus musculus 57504 R-RNO-209823 https://reactome.org/PathwayBrowser/#/R-RNO-209823 Tyrosine is hydroxylated to dopa IEA Rattus norvegicus 57504 R-RNO-209924 https://reactome.org/PathwayBrowser/#/R-RNO-209924 Dopa is decarboxylated to dopamine IEA Rattus norvegicus 57504 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 57504 R-RNO-5662692 https://reactome.org/PathwayBrowser/#/R-RNO-5662692 Dopa is oxidized to dopaquinone by TYR IEA Rattus norvegicus 57504 R-RNO-5663050 https://reactome.org/PathwayBrowser/#/R-RNO-5663050 DHI and DHICA polymerize forming eumelanin IEA Rattus norvegicus 57504 R-RNO-8851298 https://reactome.org/PathwayBrowser/#/R-RNO-8851298 GPR143 binds L-Dopa IEA Rattus norvegicus 57504 R-SSC-209823 https://reactome.org/PathwayBrowser/#/R-SSC-209823 Tyrosine is hydroxylated to dopa IEA Sus scrofa 57504 R-SSC-209924 https://reactome.org/PathwayBrowser/#/R-SSC-209924 Dopa is decarboxylated to dopamine IEA Sus scrofa 57504 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 57504 R-SSC-5662692 https://reactome.org/PathwayBrowser/#/R-SSC-5662692 Dopa is oxidized to dopaquinone by TYR IEA Sus scrofa 57504 R-SSC-5663050 https://reactome.org/PathwayBrowser/#/R-SSC-5663050 DHI and DHICA polymerize forming eumelanin IEA Sus scrofa 57504 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 57504 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 57504 R-SSC-8851298 https://reactome.org/PathwayBrowser/#/R-SSC-8851298 GPR143 binds L-Dopa IEA Sus scrofa 57504 R-XTR-209823 https://reactome.org/PathwayBrowser/#/R-XTR-209823 Tyrosine is hydroxylated to dopa IEA Xenopus tropicalis 57504 R-XTR-209924 https://reactome.org/PathwayBrowser/#/R-XTR-209924 Dopa is decarboxylated to dopamine IEA Xenopus tropicalis 57504 R-XTR-5662692 https://reactome.org/PathwayBrowser/#/R-XTR-5662692 Dopa is oxidized to dopaquinone by TYR IEA Xenopus tropicalis 57504 R-XTR-5663050 https://reactome.org/PathwayBrowser/#/R-XTR-5663050 DHI and DHICA polymerize forming eumelanin IEA Xenopus tropicalis 57504 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 57504 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 57504 R-XTR-8851298 https://reactome.org/PathwayBrowser/#/R-XTR-8851298 GPR143 binds L-Dopa IEA Xenopus tropicalis 57506 R-BTA-209840 https://reactome.org/PathwayBrowser/#/R-BTA-209840 Two DITs combine to form thyroxine IEA Bos taurus 57506 R-BTA-209925 https://reactome.org/PathwayBrowser/#/R-BTA-209925 DIT and MIT combine to form triiodothyronine IEA Bos taurus 57506 R-BTA-209960 https://reactome.org/PathwayBrowser/#/R-BTA-209960 Diiodinated tyrosine can be deiodinated IEA Bos taurus 57506 R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 57506 R-CEL-209840 https://reactome.org/PathwayBrowser/#/R-CEL-209840 Two DITs combine to form thyroxine IEA Caenorhabditis elegans 57506 R-CEL-209925 https://reactome.org/PathwayBrowser/#/R-CEL-209925 DIT and MIT combine to form triiodothyronine IEA Caenorhabditis elegans 57506 R-CEL-209960 https://reactome.org/PathwayBrowser/#/R-CEL-209960 Diiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 57506 R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 57506 R-CFA-209840 https://reactome.org/PathwayBrowser/#/R-CFA-209840 Two DITs combine to form thyroxine IEA Canis familiaris 57506 R-CFA-209925 https://reactome.org/PathwayBrowser/#/R-CFA-209925 DIT and MIT combine to form triiodothyronine IEA Canis familiaris 57506 R-CFA-209960 https://reactome.org/PathwayBrowser/#/R-CFA-209960 Diiodinated tyrosine can be deiodinated IEA Canis familiaris 57506 R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 57506 R-DDI-209840 https://reactome.org/PathwayBrowser/#/R-DDI-209840 Two DITs combine to form thyroxine IEA Dictyostelium discoideum 57506 R-DDI-209925 https://reactome.org/PathwayBrowser/#/R-DDI-209925 DIT and MIT combine to form triiodothyronine IEA Dictyostelium discoideum 57506 R-DDI-209973 https://reactome.org/PathwayBrowser/#/R-DDI-209973 Tyrosine is diiodinated IEA Dictyostelium discoideum 57506 R-DME-209840 https://reactome.org/PathwayBrowser/#/R-DME-209840 Two DITs combine to form thyroxine IEA Drosophila melanogaster 57506 R-DME-209925 https://reactome.org/PathwayBrowser/#/R-DME-209925 DIT and MIT combine to form triiodothyronine IEA Drosophila melanogaster 57506 R-DME-209960 https://reactome.org/PathwayBrowser/#/R-DME-209960 Diiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 57506 R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 57506 R-DRE-209960 https://reactome.org/PathwayBrowser/#/R-DRE-209960 Diiodinated tyrosine can be deiodinated IEA Danio rerio 57506 R-GGA-209840 https://reactome.org/PathwayBrowser/#/R-GGA-209840 Two DITs combine to form thyroxine IEA Gallus gallus 57506 R-GGA-209925 https://reactome.org/PathwayBrowser/#/R-GGA-209925 DIT and MIT combine to form triiodothyronine IEA Gallus gallus 57506 R-GGA-209960 https://reactome.org/PathwayBrowser/#/R-GGA-209960 Diiodinated tyrosine can be deiodinated IEA Gallus gallus 57506 R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 57506 R-HSA-209840 https://reactome.org/PathwayBrowser/#/R-HSA-209840 Two DITs combine to form thyroxine TAS Homo sapiens 57506 R-HSA-209925 https://reactome.org/PathwayBrowser/#/R-HSA-209925 DIT and MIT combine to form triiodothyronine TAS Homo sapiens 57506 R-HSA-209960 https://reactome.org/PathwayBrowser/#/R-HSA-209960 Diiodinated tyrosine can be deiodinated TAS Homo sapiens 57506 R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 57506 R-MMU-209840 https://reactome.org/PathwayBrowser/#/R-MMU-209840 Two DITs combine to form thyroxine IEA Mus musculus 57506 R-MMU-209925 https://reactome.org/PathwayBrowser/#/R-MMU-209925 DIT and MIT combine to form triiodothyronine IEA Mus musculus 57506 R-MMU-209960 https://reactome.org/PathwayBrowser/#/R-MMU-209960 Diiodinated tyrosine can be deiodinated IEA Mus musculus 57506 R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 57506 R-RNO-209840 https://reactome.org/PathwayBrowser/#/R-RNO-209840 Two DITs combine to form thyroxine IEA Rattus norvegicus 57506 R-RNO-209925 https://reactome.org/PathwayBrowser/#/R-RNO-209925 DIT and MIT combine to form triiodothyronine IEA Rattus norvegicus 57506 R-RNO-209960 https://reactome.org/PathwayBrowser/#/R-RNO-209960 Diiodinated tyrosine can be deiodinated IEA Rattus norvegicus 57506 R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 57506 R-SSC-209840 https://reactome.org/PathwayBrowser/#/R-SSC-209840 Two DITs combine to form thyroxine IEA Sus scrofa 57506 R-SSC-209925 https://reactome.org/PathwayBrowser/#/R-SSC-209925 DIT and MIT combine to form triiodothyronine IEA Sus scrofa 57506 R-SSC-209960 https://reactome.org/PathwayBrowser/#/R-SSC-209960 Diiodinated tyrosine can be deiodinated IEA Sus scrofa 57506 R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 57506 R-XTR-209960 https://reactome.org/PathwayBrowser/#/R-XTR-209960 Diiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 57513 R-BTA-446185 https://reactome.org/PathwayBrowser/#/R-BTA-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Bos taurus 57513 R-BTA-449734 https://reactome.org/PathwayBrowser/#/R-BTA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Bos taurus 57513 R-BTA-6803771 https://reactome.org/PathwayBrowser/#/R-BTA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Bos taurus 57513 R-CEL-446185 https://reactome.org/PathwayBrowser/#/R-CEL-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Caenorhabditis elegans 57513 R-CEL-449734 https://reactome.org/PathwayBrowser/#/R-CEL-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Caenorhabditis elegans 57513 R-CEL-6803771 https://reactome.org/PathwayBrowser/#/R-CEL-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Caenorhabditis elegans 57513 R-CFA-446185 https://reactome.org/PathwayBrowser/#/R-CFA-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Canis familiaris 57513 R-CFA-449734 https://reactome.org/PathwayBrowser/#/R-CFA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Canis familiaris 57513 R-CFA-6803771 https://reactome.org/PathwayBrowser/#/R-CFA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Canis familiaris 57513 R-DDI-449734 https://reactome.org/PathwayBrowser/#/R-DDI-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Dictyostelium discoideum 57513 R-DME-446185 https://reactome.org/PathwayBrowser/#/R-DME-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Drosophila melanogaster 57513 R-DME-449734 https://reactome.org/PathwayBrowser/#/R-DME-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Drosophila melanogaster 57513 R-DME-6803771 https://reactome.org/PathwayBrowser/#/R-DME-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Drosophila melanogaster 57513 R-DRE-449734 https://reactome.org/PathwayBrowser/#/R-DRE-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Danio rerio 57513 R-GGA-446185 https://reactome.org/PathwayBrowser/#/R-GGA-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Gallus gallus 57513 R-GGA-449734 https://reactome.org/PathwayBrowser/#/R-GGA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Gallus gallus 57513 R-GGA-6803771 https://reactome.org/PathwayBrowser/#/R-GGA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Gallus gallus 57513 R-HSA-446185 https://reactome.org/PathwayBrowser/#/R-HSA-446185 Isomerization of GlcNAc6P to GlcNAc1P TAS Homo sapiens 57513 R-HSA-449734 https://reactome.org/PathwayBrowser/#/R-HSA-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P TAS Homo sapiens 57513 R-HSA-6803771 https://reactome.org/PathwayBrowser/#/R-HSA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P TAS Homo sapiens 57513 R-MMU-446185 https://reactome.org/PathwayBrowser/#/R-MMU-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Mus musculus 57513 R-MMU-449734 https://reactome.org/PathwayBrowser/#/R-MMU-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Mus musculus 57513 R-MMU-6803771 https://reactome.org/PathwayBrowser/#/R-MMU-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Mus musculus 57513 R-PFA-446185 https://reactome.org/PathwayBrowser/#/R-PFA-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Plasmodium falciparum 57513 R-RNO-446185 https://reactome.org/PathwayBrowser/#/R-RNO-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Rattus norvegicus 57513 R-RNO-449734 https://reactome.org/PathwayBrowser/#/R-RNO-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Rattus norvegicus 57513 R-RNO-6803771 https://reactome.org/PathwayBrowser/#/R-RNO-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Rattus norvegicus 57513 R-SCE-446185 https://reactome.org/PathwayBrowser/#/R-SCE-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Saccharomyces cerevisiae 57513 R-SCE-449734 https://reactome.org/PathwayBrowser/#/R-SCE-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Saccharomyces cerevisiae 57513 R-SPO-446185 https://reactome.org/PathwayBrowser/#/R-SPO-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Schizosaccharomyces pombe 57513 R-SPO-449734 https://reactome.org/PathwayBrowser/#/R-SPO-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Schizosaccharomyces pombe 57513 R-SSC-446185 https://reactome.org/PathwayBrowser/#/R-SSC-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Sus scrofa 57513 R-SSC-449734 https://reactome.org/PathwayBrowser/#/R-SSC-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Sus scrofa 57513 R-SSC-6803771 https://reactome.org/PathwayBrowser/#/R-SSC-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Sus scrofa 57513 R-XTR-449734 https://reactome.org/PathwayBrowser/#/R-XTR-449734 Acetylation of glucosamine 6-phosphate to GlcNAc6P IEA Xenopus tropicalis 57523 R-BTA-162721 https://reactome.org/PathwayBrowser/#/R-BTA-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Bos taurus 57523 R-BTA-162797 https://reactome.org/PathwayBrowser/#/R-BTA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Bos taurus 57523 R-BTA-162821 https://reactome.org/PathwayBrowser/#/R-BTA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Bos taurus 57523 R-BTA-162873 https://reactome.org/PathwayBrowser/#/R-BTA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Bos taurus 57523 R-BTA-446188 https://reactome.org/PathwayBrowser/#/R-BTA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Bos taurus 57523 R-BTA-446198 https://reactome.org/PathwayBrowser/#/R-BTA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Bos taurus 57523 R-BTA-446215 https://reactome.org/PathwayBrowser/#/R-BTA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Bos taurus 57523 R-BTA-446216 https://reactome.org/PathwayBrowser/#/R-BTA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Bos taurus 57523 R-BTA-5615637 https://reactome.org/PathwayBrowser/#/R-BTA-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Bos taurus 57523 R-CEL-162821 https://reactome.org/PathwayBrowser/#/R-CEL-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Caenorhabditis elegans 57523 R-CEL-162873 https://reactome.org/PathwayBrowser/#/R-CEL-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Caenorhabditis elegans 57523 R-CEL-446188 https://reactome.org/PathwayBrowser/#/R-CEL-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Caenorhabditis elegans 57523 R-CEL-446198 https://reactome.org/PathwayBrowser/#/R-CEL-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Caenorhabditis elegans 57523 R-CEL-446215 https://reactome.org/PathwayBrowser/#/R-CEL-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Caenorhabditis elegans 57523 R-CEL-446216 https://reactome.org/PathwayBrowser/#/R-CEL-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Caenorhabditis elegans 57523 R-CFA-162797 https://reactome.org/PathwayBrowser/#/R-CFA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Canis familiaris 57523 R-CFA-162821 https://reactome.org/PathwayBrowser/#/R-CFA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 57523 R-CFA-162830 https://reactome.org/PathwayBrowser/#/R-CFA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 57523 R-CFA-162873 https://reactome.org/PathwayBrowser/#/R-CFA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 57523 R-CFA-446188 https://reactome.org/PathwayBrowser/#/R-CFA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Canis familiaris 57523 R-CFA-446198 https://reactome.org/PathwayBrowser/#/R-CFA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Canis familiaris 57523 R-CFA-446215 https://reactome.org/PathwayBrowser/#/R-CFA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Canis familiaris 57523 R-CFA-446216 https://reactome.org/PathwayBrowser/#/R-CFA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Canis familiaris 57523 R-CFA-5615637 https://reactome.org/PathwayBrowser/#/R-CFA-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Canis familiaris 57523 R-DDI-162797 https://reactome.org/PathwayBrowser/#/R-DDI-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Dictyostelium discoideum 57523 R-DDI-162821 https://reactome.org/PathwayBrowser/#/R-DDI-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 57523 R-DDI-162830 https://reactome.org/PathwayBrowser/#/R-DDI-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 57523 R-DDI-162873 https://reactome.org/PathwayBrowser/#/R-DDI-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 57523 R-DDI-446188 https://reactome.org/PathwayBrowser/#/R-DDI-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Dictyostelium discoideum 57523 R-DDI-446198 https://reactome.org/PathwayBrowser/#/R-DDI-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Dictyostelium discoideum 57523 R-DDI-446215 https://reactome.org/PathwayBrowser/#/R-DDI-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Dictyostelium discoideum 57523 R-DDI-446216 https://reactome.org/PathwayBrowser/#/R-DDI-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Dictyostelium discoideum 57523 R-DME-162797 https://reactome.org/PathwayBrowser/#/R-DME-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Drosophila melanogaster 57523 R-DME-162821 https://reactome.org/PathwayBrowser/#/R-DME-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 57523 R-DME-162830 https://reactome.org/PathwayBrowser/#/R-DME-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 57523 R-DME-162873 https://reactome.org/PathwayBrowser/#/R-DME-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 57523 R-DME-446188 https://reactome.org/PathwayBrowser/#/R-DME-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Drosophila melanogaster 57523 R-DME-446198 https://reactome.org/PathwayBrowser/#/R-DME-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Drosophila melanogaster 57523 R-DME-446215 https://reactome.org/PathwayBrowser/#/R-DME-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Drosophila melanogaster 57523 R-DME-446216 https://reactome.org/PathwayBrowser/#/R-DME-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Drosophila melanogaster 57523 R-DME-5615637 https://reactome.org/PathwayBrowser/#/R-DME-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Drosophila melanogaster 57523 R-DRE-162721 https://reactome.org/PathwayBrowser/#/R-DRE-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Danio rerio 57523 R-DRE-162821 https://reactome.org/PathwayBrowser/#/R-DRE-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Danio rerio 57523 R-DRE-446188 https://reactome.org/PathwayBrowser/#/R-DRE-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Danio rerio 57523 R-DRE-446198 https://reactome.org/PathwayBrowser/#/R-DRE-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Danio rerio 57523 R-DRE-5615637 https://reactome.org/PathwayBrowser/#/R-DRE-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Danio rerio 57523 R-GGA-162797 https://reactome.org/PathwayBrowser/#/R-GGA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Gallus gallus 57523 R-GGA-162830 https://reactome.org/PathwayBrowser/#/R-GGA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Gallus gallus 57523 R-GGA-162873 https://reactome.org/PathwayBrowser/#/R-GGA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Gallus gallus 57523 R-GGA-446188 https://reactome.org/PathwayBrowser/#/R-GGA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Gallus gallus 57523 R-GGA-446198 https://reactome.org/PathwayBrowser/#/R-GGA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Gallus gallus 57523 R-GGA-446215 https://reactome.org/PathwayBrowser/#/R-GGA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Gallus gallus 57523 R-GGA-446216 https://reactome.org/PathwayBrowser/#/R-GGA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Gallus gallus 57523 R-GGA-5615637 https://reactome.org/PathwayBrowser/#/R-GGA-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Gallus gallus 57523 R-HSA-162715 https://reactome.org/PathwayBrowser/#/R-HSA-162715 Reorientation of dolichyl phosphate D-mannose in the endoplasmic reticulum membrane TAS Homo sapiens 57523 R-HSA-162721 https://reactome.org/PathwayBrowser/#/R-HSA-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose TAS Homo sapiens 57523 R-HSA-162797 https://reactome.org/PathwayBrowser/#/R-HSA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI TAS Homo sapiens 57523 R-HSA-162821 https://reactome.org/PathwayBrowser/#/R-HSA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 57523 R-HSA-162830 https://reactome.org/PathwayBrowser/#/R-HSA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 57523 R-HSA-162873 https://reactome.org/PathwayBrowser/#/R-HSA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 57523 R-HSA-446188 https://reactome.org/PathwayBrowser/#/R-HSA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 TAS Homo sapiens 57523 R-HSA-446198 https://reactome.org/PathwayBrowser/#/R-HSA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 TAS Homo sapiens 57523 R-HSA-446215 https://reactome.org/PathwayBrowser/#/R-HSA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 TAS Homo sapiens 57523 R-HSA-446216 https://reactome.org/PathwayBrowser/#/R-HSA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 TAS Homo sapiens 57523 R-HSA-4686998 https://reactome.org/PathwayBrowser/#/R-HSA-4686998 Defective MPDU1 does not promote transfer of Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 by ALG12 TAS Homo sapiens 57523 R-HSA-4720473 https://reactome.org/PathwayBrowser/#/R-HSA-4720473 Defective ALG3 does not add mannose to the N-glycan precursor TAS Homo sapiens 57523 R-HSA-4720478 https://reactome.org/PathwayBrowser/#/R-HSA-4720478 Defective ALG9 does not add the seventh mannose to the N-glycan precursor TAS Homo sapiens 57523 R-HSA-4720497 https://reactome.org/PathwayBrowser/#/R-HSA-4720497 Defective ALG12 does not add mannose to the N-glycan precursor TAS Homo sapiens 57523 R-HSA-5615556 https://reactome.org/PathwayBrowser/#/R-HSA-5615556 Defective POMT2 does not transfer Man from Dol-P-Man to DAG1 TAS Homo sapiens 57523 R-HSA-5615604 https://reactome.org/PathwayBrowser/#/R-HSA-5615604 Defective POMT1 does not transfer Man from Dol-P-Man to DAG1 TAS Homo sapiens 57523 R-HSA-5615637 https://reactome.org/PathwayBrowser/#/R-HSA-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) TAS Homo sapiens 57523 R-HSA-9035514 https://reactome.org/PathwayBrowser/#/R-HSA-9035514 Defective ALG9 does not add the last mannose to the N-glycan precursor TAS Homo sapiens 57523 R-HSA-9036020 https://reactome.org/PathwayBrowser/#/R-HSA-9036020 Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)8 (PP-Dol)1 by ALG9 TAS Homo sapiens 57523 R-HSA-9036021 https://reactome.org/PathwayBrowser/#/R-HSA-9036021 Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)6 (PP-Dol)1 by ALG9 TAS Homo sapiens 57523 R-HSA-9036025 https://reactome.org/PathwayBrowser/#/R-HSA-9036025 Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)5 (PP-Dol)1 by ALG3 TAS Homo sapiens 57523 R-MMU-162721 https://reactome.org/PathwayBrowser/#/R-MMU-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Mus musculus 57523 R-MMU-162797 https://reactome.org/PathwayBrowser/#/R-MMU-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Mus musculus 57523 R-MMU-162821 https://reactome.org/PathwayBrowser/#/R-MMU-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 57523 R-MMU-162830 https://reactome.org/PathwayBrowser/#/R-MMU-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 57523 R-MMU-162873 https://reactome.org/PathwayBrowser/#/R-MMU-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 57523 R-MMU-446188 https://reactome.org/PathwayBrowser/#/R-MMU-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Mus musculus 57523 R-MMU-446198 https://reactome.org/PathwayBrowser/#/R-MMU-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Mus musculus 57523 R-MMU-446215 https://reactome.org/PathwayBrowser/#/R-MMU-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Mus musculus 57523 R-MMU-446216 https://reactome.org/PathwayBrowser/#/R-MMU-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Mus musculus 57523 R-MMU-5615637 https://reactome.org/PathwayBrowser/#/R-MMU-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Mus musculus 57523 R-PFA-162821 https://reactome.org/PathwayBrowser/#/R-PFA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Plasmodium falciparum 57523 R-PFA-162873 https://reactome.org/PathwayBrowser/#/R-PFA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Plasmodium falciparum 57523 R-RNO-162721 https://reactome.org/PathwayBrowser/#/R-RNO-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Rattus norvegicus 57523 R-RNO-162821 https://reactome.org/PathwayBrowser/#/R-RNO-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 57523 R-RNO-162830 https://reactome.org/PathwayBrowser/#/R-RNO-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 57523 R-RNO-162873 https://reactome.org/PathwayBrowser/#/R-RNO-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 57523 R-RNO-446188 https://reactome.org/PathwayBrowser/#/R-RNO-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Rattus norvegicus 57523 R-RNO-446198 https://reactome.org/PathwayBrowser/#/R-RNO-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Rattus norvegicus 57523 R-RNO-446215 https://reactome.org/PathwayBrowser/#/R-RNO-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Rattus norvegicus 57523 R-RNO-446216 https://reactome.org/PathwayBrowser/#/R-RNO-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Rattus norvegicus 57523 R-RNO-5615637 https://reactome.org/PathwayBrowser/#/R-RNO-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Rattus norvegicus 57523 R-SCE-162797 https://reactome.org/PathwayBrowser/#/R-SCE-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Saccharomyces cerevisiae 57523 R-SCE-162821 https://reactome.org/PathwayBrowser/#/R-SCE-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Saccharomyces cerevisiae 57523 R-SCE-162873 https://reactome.org/PathwayBrowser/#/R-SCE-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Saccharomyces cerevisiae 57523 R-SCE-446188 https://reactome.org/PathwayBrowser/#/R-SCE-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Saccharomyces cerevisiae 57523 R-SCE-446198 https://reactome.org/PathwayBrowser/#/R-SCE-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Saccharomyces cerevisiae 57523 R-SCE-446215 https://reactome.org/PathwayBrowser/#/R-SCE-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Saccharomyces cerevisiae 57523 R-SCE-446216 https://reactome.org/PathwayBrowser/#/R-SCE-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Saccharomyces cerevisiae 57523 R-SPO-162797 https://reactome.org/PathwayBrowser/#/R-SPO-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Schizosaccharomyces pombe 57523 R-SPO-162821 https://reactome.org/PathwayBrowser/#/R-SPO-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Schizosaccharomyces pombe 57523 R-SPO-162873 https://reactome.org/PathwayBrowser/#/R-SPO-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Schizosaccharomyces pombe 57523 R-SPO-446188 https://reactome.org/PathwayBrowser/#/R-SPO-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Schizosaccharomyces pombe 57523 R-SPO-446198 https://reactome.org/PathwayBrowser/#/R-SPO-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Schizosaccharomyces pombe 57523 R-SPO-446215 https://reactome.org/PathwayBrowser/#/R-SPO-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Schizosaccharomyces pombe 57523 R-SPO-446216 https://reactome.org/PathwayBrowser/#/R-SPO-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Schizosaccharomyces pombe 57523 R-SSC-162721 https://reactome.org/PathwayBrowser/#/R-SSC-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Sus scrofa 57523 R-SSC-162797 https://reactome.org/PathwayBrowser/#/R-SSC-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Sus scrofa 57523 R-SSC-162821 https://reactome.org/PathwayBrowser/#/R-SSC-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Sus scrofa 57523 R-SSC-162873 https://reactome.org/PathwayBrowser/#/R-SSC-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Sus scrofa 57523 R-SSC-446188 https://reactome.org/PathwayBrowser/#/R-SSC-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Sus scrofa 57523 R-SSC-446198 https://reactome.org/PathwayBrowser/#/R-SSC-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Sus scrofa 57523 R-SSC-446215 https://reactome.org/PathwayBrowser/#/R-SSC-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Sus scrofa 57523 R-SSC-446216 https://reactome.org/PathwayBrowser/#/R-SSC-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Sus scrofa 57523 R-SSC-5615637 https://reactome.org/PathwayBrowser/#/R-SSC-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Sus scrofa 57523 R-XTR-162721 https://reactome.org/PathwayBrowser/#/R-XTR-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Xenopus tropicalis 57523 R-XTR-162821 https://reactome.org/PathwayBrowser/#/R-XTR-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 57523 R-XTR-162830 https://reactome.org/PathwayBrowser/#/R-XTR-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 57523 R-XTR-162873 https://reactome.org/PathwayBrowser/#/R-XTR-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 57523 R-XTR-446188 https://reactome.org/PathwayBrowser/#/R-XTR-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Xenopus tropicalis 57523 R-XTR-446215 https://reactome.org/PathwayBrowser/#/R-XTR-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Xenopus tropicalis 57523 R-XTR-446216 https://reactome.org/PathwayBrowser/#/R-XTR-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Xenopus tropicalis 57523 R-XTR-5615637 https://reactome.org/PathwayBrowser/#/R-XTR-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Xenopus tropicalis 57527 R-BTA-162721 https://reactome.org/PathwayBrowser/#/R-BTA-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Bos taurus 57527 R-BTA-446208 https://reactome.org/PathwayBrowser/#/R-BTA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Bos taurus 57527 R-BTA-446218 https://reactome.org/PathwayBrowser/#/R-BTA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Bos taurus 57527 R-BTA-6787632 https://reactome.org/PathwayBrowser/#/R-BTA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Bos taurus 57527 R-BTA-744230 https://reactome.org/PathwayBrowser/#/R-BTA-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Bos taurus 57527 R-CEL-446208 https://reactome.org/PathwayBrowser/#/R-CEL-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Caenorhabditis elegans 57527 R-CEL-446218 https://reactome.org/PathwayBrowser/#/R-CEL-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Caenorhabditis elegans 57527 R-CEL-6787632 https://reactome.org/PathwayBrowser/#/R-CEL-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Caenorhabditis elegans 57527 R-CEL-744230 https://reactome.org/PathwayBrowser/#/R-CEL-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Caenorhabditis elegans 57527 R-CFA-446208 https://reactome.org/PathwayBrowser/#/R-CFA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Canis familiaris 57527 R-CFA-446218 https://reactome.org/PathwayBrowser/#/R-CFA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Canis familiaris 57527 R-CFA-6787632 https://reactome.org/PathwayBrowser/#/R-CFA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Canis familiaris 57527 R-CFA-744230 https://reactome.org/PathwayBrowser/#/R-CFA-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Canis familiaris 57527 R-DDI-446208 https://reactome.org/PathwayBrowser/#/R-DDI-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Dictyostelium discoideum 57527 R-DDI-446218 https://reactome.org/PathwayBrowser/#/R-DDI-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Dictyostelium discoideum 57527 R-DDI-6787632 https://reactome.org/PathwayBrowser/#/R-DDI-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Dictyostelium discoideum 57527 R-DDI-744230 https://reactome.org/PathwayBrowser/#/R-DDI-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Dictyostelium discoideum 57527 R-DME-446208 https://reactome.org/PathwayBrowser/#/R-DME-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Drosophila melanogaster 57527 R-DME-446218 https://reactome.org/PathwayBrowser/#/R-DME-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Drosophila melanogaster 57527 R-DME-6787632 https://reactome.org/PathwayBrowser/#/R-DME-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Drosophila melanogaster 57527 R-DME-744230 https://reactome.org/PathwayBrowser/#/R-DME-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Drosophila melanogaster 57527 R-DRE-162721 https://reactome.org/PathwayBrowser/#/R-DRE-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Danio rerio 57527 R-DRE-446218 https://reactome.org/PathwayBrowser/#/R-DRE-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Danio rerio 57527 R-GGA-446208 https://reactome.org/PathwayBrowser/#/R-GGA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Gallus gallus 57527 R-GGA-446218 https://reactome.org/PathwayBrowser/#/R-GGA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Gallus gallus 57527 R-GGA-6787632 https://reactome.org/PathwayBrowser/#/R-GGA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Gallus gallus 57527 R-GGA-744230 https://reactome.org/PathwayBrowser/#/R-GGA-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Gallus gallus 57527 R-HSA-162721 https://reactome.org/PathwayBrowser/#/R-HSA-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose TAS Homo sapiens 57527 R-HSA-446187 https://reactome.org/PathwayBrowser/#/R-HSA-446187 ALG11 transfers the fourth and fifth Man to the N-glycan precursor IEA Homo sapiens 57527 R-HSA-446208 https://reactome.org/PathwayBrowser/#/R-HSA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 TAS Homo sapiens 57527 R-HSA-446218 https://reactome.org/PathwayBrowser/#/R-HSA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 TAS Homo sapiens 57527 R-HSA-446221 https://reactome.org/PathwayBrowser/#/R-HSA-446221 Mannose-1-phosphate converted to GDP-Mannose IEA Homo sapiens 57527 R-HSA-449718 https://reactome.org/PathwayBrowser/#/R-HSA-449718 Addition of a third mannose to the N-glycan precursor by ALG2 IEA Homo sapiens 57527 R-HSA-4549368 https://reactome.org/PathwayBrowser/#/R-HSA-4549368 Defective ALG2 does not transfer a second Man to N-glycan precursor TAS Homo sapiens 57527 R-HSA-4549382 https://reactome.org/PathwayBrowser/#/R-HSA-4549382 Defective ALG1 does not transfer the first Man to the N-glycan precursor TAS Homo sapiens 57527 R-HSA-4551297 https://reactome.org/PathwayBrowser/#/R-HSA-4551297 Defective ALG11 does not transfer Man to the N-glycan precursor TAS Homo sapiens 57527 R-HSA-4717406 https://reactome.org/PathwayBrowser/#/R-HSA-4717406 Defective DPM1 does not transfer mannose to DOLP to form DOLPman TAS Homo sapiens 57527 R-HSA-4719354 https://reactome.org/PathwayBrowser/#/R-HSA-4719354 Defective DPM3 does not transfer mannose to DOLP to form DOLPman TAS Homo sapiens 57527 R-HSA-4719375 https://reactome.org/PathwayBrowser/#/R-HSA-4719375 Defective DPM2 does not transfer mannose to DOLP to form DOLPman TAS Homo sapiens 57527 R-HSA-6787632 https://reactome.org/PathwayBrowser/#/R-HSA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan TAS Homo sapiens 57527 R-HSA-744230 https://reactome.org/PathwayBrowser/#/R-HSA-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP TAS Homo sapiens 57527 R-MMU-162721 https://reactome.org/PathwayBrowser/#/R-MMU-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Mus musculus 57527 R-MMU-446208 https://reactome.org/PathwayBrowser/#/R-MMU-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Mus musculus 57527 R-MMU-446218 https://reactome.org/PathwayBrowser/#/R-MMU-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Mus musculus 57527 R-MMU-6787632 https://reactome.org/PathwayBrowser/#/R-MMU-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Mus musculus 57527 R-MMU-744230 https://reactome.org/PathwayBrowser/#/R-MMU-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Mus musculus 57527 R-PFA-6787632 https://reactome.org/PathwayBrowser/#/R-PFA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Plasmodium falciparum 57527 R-RNO-162721 https://reactome.org/PathwayBrowser/#/R-RNO-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Rattus norvegicus 57527 R-RNO-446208 https://reactome.org/PathwayBrowser/#/R-RNO-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Rattus norvegicus 57527 R-RNO-446218 https://reactome.org/PathwayBrowser/#/R-RNO-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Rattus norvegicus 57527 R-RNO-6787632 https://reactome.org/PathwayBrowser/#/R-RNO-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Rattus norvegicus 57527 R-RNO-744230 https://reactome.org/PathwayBrowser/#/R-RNO-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Rattus norvegicus 57527 R-RNO-749516 https://reactome.org/PathwayBrowser/#/R-RNO-749516 Mannose-1-phosphate converted to GDP-Mannose TAS Rattus norvegicus 57527 R-SCE-446208 https://reactome.org/PathwayBrowser/#/R-SCE-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Saccharomyces cerevisiae 57527 R-SCE-446218 https://reactome.org/PathwayBrowser/#/R-SCE-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Saccharomyces cerevisiae 57527 R-SCE-449324 https://reactome.org/PathwayBrowser/#/R-SCE-449324 Addition of the fourth and fifth mannose to the N-glycan precursor skeleton by Alg11 TAS Saccharomyces cerevisiae 57527 R-SCE-449748 https://reactome.org/PathwayBrowser/#/R-SCE-449748 Addition of a third mannose to the N-glycan precursor by Alg2 TAS Saccharomyces cerevisiae 57527 R-SPO-446208 https://reactome.org/PathwayBrowser/#/R-SPO-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Schizosaccharomyces pombe 57527 R-SPO-446218 https://reactome.org/PathwayBrowser/#/R-SPO-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Schizosaccharomyces pombe 57527 R-SSC-162721 https://reactome.org/PathwayBrowser/#/R-SSC-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Sus scrofa 57527 R-SSC-446208 https://reactome.org/PathwayBrowser/#/R-SSC-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Sus scrofa 57527 R-SSC-446218 https://reactome.org/PathwayBrowser/#/R-SSC-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Sus scrofa 57527 R-SSC-6787632 https://reactome.org/PathwayBrowser/#/R-SSC-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Sus scrofa 57527 R-SSC-744230 https://reactome.org/PathwayBrowser/#/R-SSC-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Sus scrofa 57527 R-XTR-162721 https://reactome.org/PathwayBrowser/#/R-XTR-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Xenopus tropicalis 57527 R-XTR-446208 https://reactome.org/PathwayBrowser/#/R-XTR-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Xenopus tropicalis 57527 R-XTR-6787632 https://reactome.org/PathwayBrowser/#/R-XTR-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Xenopus tropicalis 57527 R-XTR-744230 https://reactome.org/PathwayBrowser/#/R-XTR-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Xenopus tropicalis 57533 R-BTA-6806674 https://reactome.org/PathwayBrowser/#/R-BTA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Bos taurus 57533 R-CFA-6806674 https://reactome.org/PathwayBrowser/#/R-CFA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Canis familiaris 57533 R-DDI-6806674 https://reactome.org/PathwayBrowser/#/R-DDI-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Dictyostelium discoideum 57533 R-DME-6806674 https://reactome.org/PathwayBrowser/#/R-DME-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 57533 R-DRE-6806674 https://reactome.org/PathwayBrowser/#/R-DRE-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Danio rerio 57533 R-GGA-6806674 https://reactome.org/PathwayBrowser/#/R-GGA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Gallus gallus 57533 R-HSA-6806674 https://reactome.org/PathwayBrowser/#/R-HSA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) TAS Homo sapiens 57533 R-MMU-6806674 https://reactome.org/PathwayBrowser/#/R-MMU-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Mus musculus 57533 R-RNO-6806674 https://reactome.org/PathwayBrowser/#/R-RNO-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 57533 R-SSC-6806674 https://reactome.org/PathwayBrowser/#/R-SSC-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Sus scrofa 57533 R-XTR-6806674 https://reactome.org/PathwayBrowser/#/R-XTR-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 57538 R-BTA-73564 https://reactome.org/PathwayBrowser/#/R-BTA-73564 UMPS dimer decarboxylates OMP to UMP IEA Bos taurus 57538 R-BTA-73567 https://reactome.org/PathwayBrowser/#/R-BTA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Bos taurus 57538 R-CEL-73564 https://reactome.org/PathwayBrowser/#/R-CEL-73564 UMPS dimer decarboxylates OMP to UMP IEA Caenorhabditis elegans 57538 R-CEL-73567 https://reactome.org/PathwayBrowser/#/R-CEL-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Caenorhabditis elegans 57538 R-CFA-73564 https://reactome.org/PathwayBrowser/#/R-CFA-73564 UMPS dimer decarboxylates OMP to UMP IEA Canis familiaris 57538 R-CFA-73567 https://reactome.org/PathwayBrowser/#/R-CFA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Canis familiaris 57538 R-DDI-73564 https://reactome.org/PathwayBrowser/#/R-DDI-73564 UMPS dimer decarboxylates OMP to UMP IEA Dictyostelium discoideum 57538 R-DDI-73567 https://reactome.org/PathwayBrowser/#/R-DDI-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Dictyostelium discoideum 57538 R-DME-73564 https://reactome.org/PathwayBrowser/#/R-DME-73564 UMPS dimer decarboxylates OMP to UMP IEA Drosophila melanogaster 57538 R-DME-73567 https://reactome.org/PathwayBrowser/#/R-DME-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Drosophila melanogaster 57538 R-GGA-419461 https://reactome.org/PathwayBrowser/#/R-GGA-419461 orotidine 5'-monophosphate => uridine 5'-monophosphate + CO2 IEA Gallus gallus 57538 R-GGA-419462 https://reactome.org/PathwayBrowser/#/R-GGA-419462 orotate + 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) <=> orotidine 5'-monophosphate (OMP) + pyrophosphate IEA Gallus gallus 57538 R-GGA-73564 https://reactome.org/PathwayBrowser/#/R-GGA-73564 UMPS dimer decarboxylates OMP to UMP IEA Gallus gallus 57538 R-GGA-73567 https://reactome.org/PathwayBrowser/#/R-GGA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Gallus gallus 57538 R-HSA-73564 https://reactome.org/PathwayBrowser/#/R-HSA-73564 UMPS dimer decarboxylates OMP to UMP TAS Homo sapiens 57538 R-HSA-73567 https://reactome.org/PathwayBrowser/#/R-HSA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP TAS Homo sapiens 57538 R-MMU-73564 https://reactome.org/PathwayBrowser/#/R-MMU-73564 UMPS dimer decarboxylates OMP to UMP IEA Mus musculus 57538 R-MMU-73567 https://reactome.org/PathwayBrowser/#/R-MMU-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Mus musculus 57538 R-RNO-73564 https://reactome.org/PathwayBrowser/#/R-RNO-73564 UMPS dimer decarboxylates OMP to UMP IEA Rattus norvegicus 57538 R-RNO-73567 https://reactome.org/PathwayBrowser/#/R-RNO-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Rattus norvegicus 57538 R-SSC-73564 https://reactome.org/PathwayBrowser/#/R-SSC-73564 UMPS dimer decarboxylates OMP to UMP IEA Sus scrofa 57538 R-SSC-73567 https://reactome.org/PathwayBrowser/#/R-SSC-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Sus scrofa 57538 R-XTR-73564 https://reactome.org/PathwayBrowser/#/R-XTR-73564 UMPS dimer decarboxylates OMP to UMP IEA Xenopus tropicalis 57538 R-XTR-73567 https://reactome.org/PathwayBrowser/#/R-XTR-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Xenopus tropicalis 57539 R-BTA-1855162 https://reactome.org/PathwayBrowser/#/R-BTA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Bos taurus 57539 R-BTA-1855219 https://reactome.org/PathwayBrowser/#/R-BTA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Bos taurus 57539 R-BTA-994137 https://reactome.org/PathwayBrowser/#/R-BTA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Bos taurus 57539 R-CFA-1855162 https://reactome.org/PathwayBrowser/#/R-CFA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Canis familiaris 57539 R-CFA-1855219 https://reactome.org/PathwayBrowser/#/R-CFA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 57539 R-CFA-994137 https://reactome.org/PathwayBrowser/#/R-CFA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Canis familiaris 57539 R-DDI-1855162 https://reactome.org/PathwayBrowser/#/R-DDI-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Dictyostelium discoideum 57539 R-DDI-1855219 https://reactome.org/PathwayBrowser/#/R-DDI-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 57539 R-DDI-994137 https://reactome.org/PathwayBrowser/#/R-DDI-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Dictyostelium discoideum 57539 R-DRE-1855162 https://reactome.org/PathwayBrowser/#/R-DRE-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Danio rerio 57539 R-DRE-1855219 https://reactome.org/PathwayBrowser/#/R-DRE-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Danio rerio 57539 R-DRE-994137 https://reactome.org/PathwayBrowser/#/R-DRE-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Danio rerio 57539 R-GGA-1855162 https://reactome.org/PathwayBrowser/#/R-GGA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Gallus gallus 57539 R-GGA-1855219 https://reactome.org/PathwayBrowser/#/R-GGA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 57539 R-GGA-994137 https://reactome.org/PathwayBrowser/#/R-GGA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Gallus gallus 57539 R-HSA-1855162 https://reactome.org/PathwayBrowser/#/R-HSA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol TAS Homo sapiens 57539 R-HSA-1855219 https://reactome.org/PathwayBrowser/#/R-HSA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 57539 R-HSA-994137 https://reactome.org/PathwayBrowser/#/R-HSA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 TAS Homo sapiens 57539 R-MMU-1855162 https://reactome.org/PathwayBrowser/#/R-MMU-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Mus musculus 57539 R-MMU-1855219 https://reactome.org/PathwayBrowser/#/R-MMU-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Mus musculus 57539 R-MMU-994137 https://reactome.org/PathwayBrowser/#/R-MMU-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Mus musculus 57539 R-RNO-1855162 https://reactome.org/PathwayBrowser/#/R-RNO-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Rattus norvegicus 57539 R-RNO-1855219 https://reactome.org/PathwayBrowser/#/R-RNO-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 57539 R-RNO-994137 https://reactome.org/PathwayBrowser/#/R-RNO-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Rattus norvegicus 57539 R-SSC-1855162 https://reactome.org/PathwayBrowser/#/R-SSC-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Sus scrofa 57539 R-SSC-1855219 https://reactome.org/PathwayBrowser/#/R-SSC-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 57539 R-SSC-994137 https://reactome.org/PathwayBrowser/#/R-SSC-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Sus scrofa 57539 R-XTR-1855162 https://reactome.org/PathwayBrowser/#/R-XTR-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Xenopus tropicalis 57539 R-XTR-1855219 https://reactome.org/PathwayBrowser/#/R-XTR-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 57539 R-XTR-994137 https://reactome.org/PathwayBrowser/#/R-XTR-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Xenopus tropicalis 57540 R-BTA-109343 https://reactome.org/PathwayBrowser/#/R-BTA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Bos taurus 57540 R-BTA-1614362 https://reactome.org/PathwayBrowser/#/R-BTA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Bos taurus 57540 R-BTA-163217 https://reactome.org/PathwayBrowser/#/R-BTA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Bos taurus 57540 R-BTA-173597 https://reactome.org/PathwayBrowser/#/R-BTA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Bos taurus 57540 R-BTA-174401 https://reactome.org/PathwayBrowser/#/R-BTA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Bos taurus 57540 R-BTA-1855178 https://reactome.org/PathwayBrowser/#/R-BTA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Bos taurus 57540 R-BTA-192097 https://reactome.org/PathwayBrowser/#/R-BTA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Bos taurus 57540 R-BTA-193073 https://reactome.org/PathwayBrowser/#/R-BTA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Bos taurus 57540 R-BTA-193455 https://reactome.org/PathwayBrowser/#/R-BTA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 57540 R-BTA-193508 https://reactome.org/PathwayBrowser/#/R-BTA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 57540 R-BTA-193789 https://reactome.org/PathwayBrowser/#/R-BTA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Bos taurus 57540 R-BTA-193816 https://reactome.org/PathwayBrowser/#/R-BTA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Bos taurus 57540 R-BTA-194642 https://reactome.org/PathwayBrowser/#/R-BTA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Bos taurus 57540 R-BTA-194718 https://reactome.org/PathwayBrowser/#/R-BTA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Bos taurus 57540 R-BTA-196350 https://reactome.org/PathwayBrowser/#/R-BTA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Bos taurus 57540 R-BTA-196372 https://reactome.org/PathwayBrowser/#/R-BTA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Bos taurus 57540 R-BTA-197198 https://reactome.org/PathwayBrowser/#/R-BTA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Bos taurus 57540 R-BTA-197271 https://reactome.org/PathwayBrowser/#/R-BTA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Bos taurus 57540 R-BTA-198824 https://reactome.org/PathwayBrowser/#/R-BTA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Bos taurus 57540 R-BTA-2046084 https://reactome.org/PathwayBrowser/#/R-BTA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Bos taurus 57540 R-BTA-2046089 https://reactome.org/PathwayBrowser/#/R-BTA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Bos taurus 57540 R-BTA-2046092 https://reactome.org/PathwayBrowser/#/R-BTA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Bos taurus 57540 R-BTA-2046096 https://reactome.org/PathwayBrowser/#/R-BTA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Bos taurus 57540 R-BTA-2046097 https://reactome.org/PathwayBrowser/#/R-BTA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 57540 R-BTA-204617 https://reactome.org/PathwayBrowser/#/R-BTA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Bos taurus 57540 R-BTA-204647 https://reactome.org/PathwayBrowser/#/R-BTA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Bos taurus 57540 R-BTA-204662 https://reactome.org/PathwayBrowser/#/R-BTA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Bos taurus 57540 R-BTA-2161779 https://reactome.org/PathwayBrowser/#/R-BTA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Bos taurus 57540 R-BTA-2162078 https://reactome.org/PathwayBrowser/#/R-BTA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Bos taurus 57540 R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 57540 R-BTA-2187325 https://reactome.org/PathwayBrowser/#/R-BTA-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Bos taurus 57540 R-BTA-2454081 https://reactome.org/PathwayBrowser/#/R-BTA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Bos taurus 57540 R-BTA-3371467 https://reactome.org/PathwayBrowser/#/R-BTA-3371467 SIRT1 deacetylates HSF1 IEA Bos taurus 57540 R-BTA-3640858 https://reactome.org/PathwayBrowser/#/R-BTA-3640858 Tankyrase ADP-ribosylates AXIN IEA Bos taurus 57540 R-BTA-380608 https://reactome.org/PathwayBrowser/#/R-BTA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Bos taurus 57540 R-BTA-389609 https://reactome.org/PathwayBrowser/#/R-BTA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Bos taurus 57540 R-BTA-389995 https://reactome.org/PathwayBrowser/#/R-BTA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Bos taurus 57540 R-BTA-390251 https://reactome.org/PathwayBrowser/#/R-BTA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 57540 R-BTA-427514 https://reactome.org/PathwayBrowser/#/R-BTA-427514 eNoSC deacetylates histone H3 IEA Bos taurus 57540 R-BTA-450971 https://reactome.org/PathwayBrowser/#/R-BTA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Bos taurus 57540 R-BTA-508369 https://reactome.org/PathwayBrowser/#/R-BTA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Bos taurus 57540 R-BTA-508473 https://reactome.org/PathwayBrowser/#/R-BTA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Bos taurus 57540 R-BTA-5226904 https://reactome.org/PathwayBrowser/#/R-BTA-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Bos taurus 57540 R-BTA-5362518 https://reactome.org/PathwayBrowser/#/R-BTA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Bos taurus 57540 R-BTA-5362522 https://reactome.org/PathwayBrowser/#/R-BTA-5362522 ALDHs oxidise atRAL to atRA IEA Bos taurus 57540 R-BTA-5362564 https://reactome.org/PathwayBrowser/#/R-BTA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Bos taurus 57540 R-BTA-5362721 https://reactome.org/PathwayBrowser/#/R-BTA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Bos taurus 57540 R-BTA-5651723 https://reactome.org/PathwayBrowser/#/R-BTA-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Bos taurus 57540 R-BTA-5652195 https://reactome.org/PathwayBrowser/#/R-BTA-5652195 SORD oxidizes D-sorbitol to Fru IEA Bos taurus 57540 R-BTA-5661290 https://reactome.org/PathwayBrowser/#/R-BTA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Bos taurus 57540 R-BTA-5662471 https://reactome.org/PathwayBrowser/#/R-BTA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Bos taurus 57540 R-BTA-5685953 https://reactome.org/PathwayBrowser/#/R-BTA-5685953 SIRT6 deacetylates RBBP8 IEA Bos taurus 57540 R-BTA-5687653 https://reactome.org/PathwayBrowser/#/R-BTA-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Bos taurus 57540 R-BTA-5688276 https://reactome.org/PathwayBrowser/#/R-BTA-5688276 SIRT4 transfers ADPRib to GLUD IEA Bos taurus 57540 R-BTA-5688289 https://reactome.org/PathwayBrowser/#/R-BTA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Bos taurus 57540 R-BTA-5688294 https://reactome.org/PathwayBrowser/#/R-BTA-5688294 SIRT5 deacetylates Cytochrome C IEA Bos taurus 57540 R-BTA-5692237 https://reactome.org/PathwayBrowser/#/R-BTA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Bos taurus 57540 R-BTA-5692261 https://reactome.org/PathwayBrowser/#/R-BTA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Bos taurus 57540 R-BTA-5694018 https://reactome.org/PathwayBrowser/#/R-BTA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Bos taurus 57540 R-BTA-5696080 https://reactome.org/PathwayBrowser/#/R-BTA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Bos taurus 57540 R-BTA-5696091 https://reactome.org/PathwayBrowser/#/R-BTA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Bos taurus 57540 R-BTA-5696101 https://reactome.org/PathwayBrowser/#/R-BTA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Bos taurus 57540 R-BTA-5696457 https://reactome.org/PathwayBrowser/#/R-BTA-5696457 BDH2 dehydrogenates 3HBA IEA Bos taurus 57540 R-BTA-5696655 https://reactome.org/PathwayBrowser/#/R-BTA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Bos taurus 57540 R-BTA-6783939 https://reactome.org/PathwayBrowser/#/R-BTA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 57540 R-BTA-6784399 https://reactome.org/PathwayBrowser/#/R-BTA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Bos taurus 57540 R-BTA-6797955 https://reactome.org/PathwayBrowser/#/R-BTA-6797955 ALDH7A1 oxidises BETALD to BET IEA Bos taurus 57540 R-BTA-6801328 https://reactome.org/PathwayBrowser/#/R-BTA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Bos taurus 57540 R-BTA-6806831 https://reactome.org/PathwayBrowser/#/R-BTA-6806831 CYB5Rs reduce MetHb to HbA IEA Bos taurus 57540 R-BTA-6808464 https://reactome.org/PathwayBrowser/#/R-BTA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Bos taurus 57540 R-BTA-6809264 https://reactome.org/PathwayBrowser/#/R-BTA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 57540 R-BTA-6813749 https://reactome.org/PathwayBrowser/#/R-BTA-6813749 ALDH1A1 oxidises GA to DGA IEA Bos taurus 57540 R-BTA-70369 https://reactome.org/PathwayBrowser/#/R-BTA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Bos taurus 57540 R-BTA-70449 https://reactome.org/PathwayBrowser/#/R-BTA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Bos taurus 57540 R-BTA-70482 https://reactome.org/PathwayBrowser/#/R-BTA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Bos taurus 57540 R-BTA-70510 https://reactome.org/PathwayBrowser/#/R-BTA-70510 LDH tetramer oxidises LACT to PYR IEA Bos taurus 57540 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Bos taurus 57540 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Bos taurus 57540 R-BTA-70664 https://reactome.org/PathwayBrowser/#/R-BTA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 57540 R-BTA-70679 https://reactome.org/PathwayBrowser/#/R-BTA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Bos taurus 57540 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 57540 R-BTA-70837 https://reactome.org/PathwayBrowser/#/R-BTA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Bos taurus 57540 R-BTA-70885 https://reactome.org/PathwayBrowser/#/R-BTA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Bos taurus 57540 R-BTA-70893 https://reactome.org/PathwayBrowser/#/R-BTA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Bos taurus 57540 R-BTA-70903 https://reactome.org/PathwayBrowser/#/R-BTA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Bos taurus 57540 R-BTA-70940 https://reactome.org/PathwayBrowser/#/R-BTA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Bos taurus 57540 R-BTA-70941 https://reactome.org/PathwayBrowser/#/R-BTA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Bos taurus 57540 R-BTA-70967 https://reactome.org/PathwayBrowser/#/R-BTA-70967 IDH3 complex decarboxylates isocitrate IEA Bos taurus 57540 R-BTA-70979 https://reactome.org/PathwayBrowser/#/R-BTA-70979 MDH2 dimer dehydrogenates MAL IEA Bos taurus 57540 R-BTA-71037 https://reactome.org/PathwayBrowser/#/R-BTA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Bos taurus 57540 R-BTA-71130 https://reactome.org/PathwayBrowser/#/R-BTA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Bos taurus 57540 R-BTA-71260 https://reactome.org/PathwayBrowser/#/R-BTA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Bos taurus 57540 R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 57540 R-BTA-71707 https://reactome.org/PathwayBrowser/#/R-BTA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Bos taurus 57540 R-BTA-71723 https://reactome.org/PathwayBrowser/#/R-BTA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Bos taurus 57540 R-BTA-71849 https://reactome.org/PathwayBrowser/#/R-BTA-71849 LDH tetramer reduces PYR to LACT IEA Bos taurus 57540 R-BTA-73794 https://reactome.org/PathwayBrowser/#/R-BTA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Bos taurus 57540 R-BTA-73912 https://reactome.org/PathwayBrowser/#/R-BTA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Bos taurus 57540 R-BTA-73920 https://reactome.org/PathwayBrowser/#/R-BTA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Bos taurus 57540 R-BTA-75889 https://reactome.org/PathwayBrowser/#/R-BTA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Bos taurus 57540 R-BTA-77254 https://reactome.org/PathwayBrowser/#/R-BTA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Bos taurus 57540 R-BTA-77283 https://reactome.org/PathwayBrowser/#/R-BTA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Bos taurus 57540 R-BTA-77303 https://reactome.org/PathwayBrowser/#/R-BTA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Bos taurus 57540 R-BTA-77312 https://reactome.org/PathwayBrowser/#/R-BTA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Bos taurus 57540 R-BTA-77323 https://reactome.org/PathwayBrowser/#/R-BTA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Bos taurus 57540 R-BTA-77331 https://reactome.org/PathwayBrowser/#/R-BTA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Bos taurus 57540 R-BTA-77342 https://reactome.org/PathwayBrowser/#/R-BTA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Bos taurus 57540 R-BTA-8870346 https://reactome.org/PathwayBrowser/#/R-BTA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Bos taurus 57540 R-BTA-888548 https://reactome.org/PathwayBrowser/#/R-BTA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Bos taurus 57540 R-BTA-8936442 https://reactome.org/PathwayBrowser/#/R-BTA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Bos taurus 57540 R-BTA-8938073 https://reactome.org/PathwayBrowser/#/R-BTA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Bos taurus 57540 R-BTA-8938076 https://reactome.org/PathwayBrowser/#/R-BTA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Bos taurus 57540 R-BTA-8939959 https://reactome.org/PathwayBrowser/#/R-BTA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Bos taurus 57540 R-BTA-8940070 https://reactome.org/PathwayBrowser/#/R-BTA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Bos taurus 57540 R-BTA-8948800 https://reactome.org/PathwayBrowser/#/R-BTA-8948800 TNKS and TNKS2 PARylate PTEN IEA Bos taurus 57540 R-BTA-8955030 https://reactome.org/PathwayBrowser/#/R-BTA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Bos taurus 57540 R-BTA-8956458 https://reactome.org/PathwayBrowser/#/R-BTA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Bos taurus 57540 R-BTA-9012268 https://reactome.org/PathwayBrowser/#/R-BTA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Bos taurus 57540 R-BTA-9023968 https://reactome.org/PathwayBrowser/#/R-BTA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Bos taurus 57540 R-BTA-9024766 https://reactome.org/PathwayBrowser/#/R-BTA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Bos taurus 57540 R-BTA-9620532 https://reactome.org/PathwayBrowser/#/R-BTA-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Bos taurus 57540 R-BTA-9667952 https://reactome.org/PathwayBrowser/#/R-BTA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Bos taurus 57540 R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 57540 R-BTA-9727349 https://reactome.org/PathwayBrowser/#/R-BTA-9727349 XDH dehydrogenates xanthine to form urate IEA Bos taurus 57540 R-BTA-9748945 https://reactome.org/PathwayBrowser/#/R-BTA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Bos taurus 57540 R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 57540 R-BTA-9759549 https://reactome.org/PathwayBrowser/#/R-BTA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Bos taurus 57540 R-BTA-977348 https://reactome.org/PathwayBrowser/#/R-BTA-977348 PHGDH tetramer dehydrogenates 3PG IEA Bos taurus 57540 R-BTA-9853499 https://reactome.org/PathwayBrowser/#/R-BTA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 57540 R-BTA-9854463 https://reactome.org/PathwayBrowser/#/R-BTA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Bos taurus 57540 R-BTA-9856871 https://reactome.org/PathwayBrowser/#/R-BTA-9856871 MDH1 reduces OA IEA Bos taurus 57540 R-BTA-9861616 https://reactome.org/PathwayBrowser/#/R-BTA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 57540 R-BTA-9861626 https://reactome.org/PathwayBrowser/#/R-BTA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Bos taurus 57540 R-CEL-109343 https://reactome.org/PathwayBrowser/#/R-CEL-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Caenorhabditis elegans 57540 R-CEL-173597 https://reactome.org/PathwayBrowser/#/R-CEL-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Caenorhabditis elegans 57540 R-CEL-174401 https://reactome.org/PathwayBrowser/#/R-CEL-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Caenorhabditis elegans 57540 R-CEL-1855178 https://reactome.org/PathwayBrowser/#/R-CEL-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Caenorhabditis elegans 57540 R-CEL-193455 https://reactome.org/PathwayBrowser/#/R-CEL-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 57540 R-CEL-193508 https://reactome.org/PathwayBrowser/#/R-CEL-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 57540 R-CEL-194642 https://reactome.org/PathwayBrowser/#/R-CEL-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Caenorhabditis elegans 57540 R-CEL-194718 https://reactome.org/PathwayBrowser/#/R-CEL-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Caenorhabditis elegans 57540 R-CEL-197271 https://reactome.org/PathwayBrowser/#/R-CEL-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Caenorhabditis elegans 57540 R-CEL-2046084 https://reactome.org/PathwayBrowser/#/R-CEL-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Caenorhabditis elegans 57540 R-CEL-2046089 https://reactome.org/PathwayBrowser/#/R-CEL-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Caenorhabditis elegans 57540 R-CEL-2046092 https://reactome.org/PathwayBrowser/#/R-CEL-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Caenorhabditis elegans 57540 R-CEL-2046096 https://reactome.org/PathwayBrowser/#/R-CEL-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Caenorhabditis elegans 57540 R-CEL-2046097 https://reactome.org/PathwayBrowser/#/R-CEL-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Caenorhabditis elegans 57540 R-CEL-204617 https://reactome.org/PathwayBrowser/#/R-CEL-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Caenorhabditis elegans 57540 R-CEL-204647 https://reactome.org/PathwayBrowser/#/R-CEL-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Caenorhabditis elegans 57540 R-CEL-204662 https://reactome.org/PathwayBrowser/#/R-CEL-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Caenorhabditis elegans 57540 R-CEL-2162078 https://reactome.org/PathwayBrowser/#/R-CEL-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Caenorhabditis elegans 57540 R-CEL-380608 https://reactome.org/PathwayBrowser/#/R-CEL-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Caenorhabditis elegans 57540 R-CEL-389609 https://reactome.org/PathwayBrowser/#/R-CEL-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Caenorhabditis elegans 57540 R-CEL-389995 https://reactome.org/PathwayBrowser/#/R-CEL-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Caenorhabditis elegans 57540 R-CEL-390251 https://reactome.org/PathwayBrowser/#/R-CEL-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 57540 R-CEL-450971 https://reactome.org/PathwayBrowser/#/R-CEL-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Caenorhabditis elegans 57540 R-CEL-508369 https://reactome.org/PathwayBrowser/#/R-CEL-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Caenorhabditis elegans 57540 R-CEL-508473 https://reactome.org/PathwayBrowser/#/R-CEL-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Caenorhabditis elegans 57540 R-CEL-5362518 https://reactome.org/PathwayBrowser/#/R-CEL-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Caenorhabditis elegans 57540 R-CEL-5362522 https://reactome.org/PathwayBrowser/#/R-CEL-5362522 ALDHs oxidise atRAL to atRA IEA Caenorhabditis elegans 57540 R-CEL-5362564 https://reactome.org/PathwayBrowser/#/R-CEL-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Caenorhabditis elegans 57540 R-CEL-5362721 https://reactome.org/PathwayBrowser/#/R-CEL-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Caenorhabditis elegans 57540 R-CEL-5652195 https://reactome.org/PathwayBrowser/#/R-CEL-5652195 SORD oxidizes D-sorbitol to Fru IEA Caenorhabditis elegans 57540 R-CEL-5661290 https://reactome.org/PathwayBrowser/#/R-CEL-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Caenorhabditis elegans 57540 R-CEL-5662471 https://reactome.org/PathwayBrowser/#/R-CEL-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Caenorhabditis elegans 57540 R-CEL-5685953 https://reactome.org/PathwayBrowser/#/R-CEL-5685953 SIRT6 deacetylates RBBP8 IEA Caenorhabditis elegans 57540 R-CEL-5688276 https://reactome.org/PathwayBrowser/#/R-CEL-5688276 SIRT4 transfers ADPRib to GLUD IEA Caenorhabditis elegans 57540 R-CEL-5692237 https://reactome.org/PathwayBrowser/#/R-CEL-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Caenorhabditis elegans 57540 R-CEL-5692261 https://reactome.org/PathwayBrowser/#/R-CEL-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Caenorhabditis elegans 57540 R-CEL-5694018 https://reactome.org/PathwayBrowser/#/R-CEL-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Caenorhabditis elegans 57540 R-CEL-5696080 https://reactome.org/PathwayBrowser/#/R-CEL-5696080 ALDH3B1 oxidises HXAL to PALM IEA Caenorhabditis elegans 57540 R-CEL-5696091 https://reactome.org/PathwayBrowser/#/R-CEL-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Caenorhabditis elegans 57540 R-CEL-5696101 https://reactome.org/PathwayBrowser/#/R-CEL-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Caenorhabditis elegans 57540 R-CEL-5696655 https://reactome.org/PathwayBrowser/#/R-CEL-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Caenorhabditis elegans 57540 R-CEL-6783939 https://reactome.org/PathwayBrowser/#/R-CEL-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 57540 R-CEL-6797955 https://reactome.org/PathwayBrowser/#/R-CEL-6797955 ALDH7A1 oxidises BETALD to BET IEA Caenorhabditis elegans 57540 R-CEL-6807826 https://reactome.org/PathwayBrowser/#/R-CEL-6807826 LDHAL6B reduces PYR to LACT IEA Caenorhabditis elegans 57540 R-CEL-6808464 https://reactome.org/PathwayBrowser/#/R-CEL-6808464 ALDH3B2 oxidises HXAL to PALM IEA Caenorhabditis elegans 57540 R-CEL-6809264 https://reactome.org/PathwayBrowser/#/R-CEL-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 57540 R-CEL-6813749 https://reactome.org/PathwayBrowser/#/R-CEL-6813749 ALDH1A1 oxidises GA to DGA IEA Caenorhabditis elegans 57540 R-CEL-70369 https://reactome.org/PathwayBrowser/#/R-CEL-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Caenorhabditis elegans 57540 R-CEL-70449 https://reactome.org/PathwayBrowser/#/R-CEL-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Caenorhabditis elegans 57540 R-CEL-70482 https://reactome.org/PathwayBrowser/#/R-CEL-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Caenorhabditis elegans 57540 R-CEL-70510 https://reactome.org/PathwayBrowser/#/R-CEL-70510 LDH tetramer oxidises LACT to PYR IEA Caenorhabditis elegans 57540 R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Caenorhabditis elegans 57540 R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Caenorhabditis elegans 57540 R-CEL-70664 https://reactome.org/PathwayBrowser/#/R-CEL-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 57540 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 57540 R-CEL-70837 https://reactome.org/PathwayBrowser/#/R-CEL-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Caenorhabditis elegans 57540 R-CEL-70885 https://reactome.org/PathwayBrowser/#/R-CEL-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Caenorhabditis elegans 57540 R-CEL-70893 https://reactome.org/PathwayBrowser/#/R-CEL-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 57540 R-CEL-70903 https://reactome.org/PathwayBrowser/#/R-CEL-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Caenorhabditis elegans 57540 R-CEL-70940 https://reactome.org/PathwayBrowser/#/R-CEL-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Caenorhabditis elegans 57540 R-CEL-70941 https://reactome.org/PathwayBrowser/#/R-CEL-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Caenorhabditis elegans 57540 R-CEL-70967 https://reactome.org/PathwayBrowser/#/R-CEL-70967 IDH3 complex decarboxylates isocitrate IEA Caenorhabditis elegans 57540 R-CEL-70979 https://reactome.org/PathwayBrowser/#/R-CEL-70979 MDH2 dimer dehydrogenates MAL IEA Caenorhabditis elegans 57540 R-CEL-71037 https://reactome.org/PathwayBrowser/#/R-CEL-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 57540 R-CEL-71130 https://reactome.org/PathwayBrowser/#/R-CEL-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Caenorhabditis elegans 57540 R-CEL-71260 https://reactome.org/PathwayBrowser/#/R-CEL-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Caenorhabditis elegans 57540 R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 57540 R-CEL-71707 https://reactome.org/PathwayBrowser/#/R-CEL-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Caenorhabditis elegans 57540 R-CEL-71723 https://reactome.org/PathwayBrowser/#/R-CEL-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Caenorhabditis elegans 57540 R-CEL-71849 https://reactome.org/PathwayBrowser/#/R-CEL-71849 LDH tetramer reduces PYR to LACT IEA Caenorhabditis elegans 57540 R-CEL-73794 https://reactome.org/PathwayBrowser/#/R-CEL-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Caenorhabditis elegans 57540 R-CEL-75889 https://reactome.org/PathwayBrowser/#/R-CEL-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Caenorhabditis elegans 57540 R-CEL-77254 https://reactome.org/PathwayBrowser/#/R-CEL-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 57540 R-CEL-77283 https://reactome.org/PathwayBrowser/#/R-CEL-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 57540 R-CEL-77303 https://reactome.org/PathwayBrowser/#/R-CEL-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Caenorhabditis elegans 57540 R-CEL-77312 https://reactome.org/PathwayBrowser/#/R-CEL-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Caenorhabditis elegans 57540 R-CEL-77323 https://reactome.org/PathwayBrowser/#/R-CEL-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Caenorhabditis elegans 57540 R-CEL-77331 https://reactome.org/PathwayBrowser/#/R-CEL-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Caenorhabditis elegans 57540 R-CEL-77342 https://reactome.org/PathwayBrowser/#/R-CEL-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 57540 R-CEL-888548 https://reactome.org/PathwayBrowser/#/R-CEL-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Caenorhabditis elegans 57540 R-CEL-8936442 https://reactome.org/PathwayBrowser/#/R-CEL-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Caenorhabditis elegans 57540 R-CEL-8939959 https://reactome.org/PathwayBrowser/#/R-CEL-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Caenorhabditis elegans 57540 R-CEL-8955030 https://reactome.org/PathwayBrowser/#/R-CEL-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Caenorhabditis elegans 57540 R-CEL-9012268 https://reactome.org/PathwayBrowser/#/R-CEL-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 57540 R-CEL-9620532 https://reactome.org/PathwayBrowser/#/R-CEL-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Caenorhabditis elegans 57540 R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 57540 R-CEL-9727349 https://reactome.org/PathwayBrowser/#/R-CEL-9727349 XDH dehydrogenates xanthine to form urate IEA Caenorhabditis elegans 57540 R-CEL-9748945 https://reactome.org/PathwayBrowser/#/R-CEL-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Caenorhabditis elegans 57540 R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 57540 R-CEL-9759549 https://reactome.org/PathwayBrowser/#/R-CEL-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Caenorhabditis elegans 57540 R-CEL-977348 https://reactome.org/PathwayBrowser/#/R-CEL-977348 PHGDH tetramer dehydrogenates 3PG IEA Caenorhabditis elegans 57540 R-CEL-9853499 https://reactome.org/PathwayBrowser/#/R-CEL-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 57540 R-CEL-9856871 https://reactome.org/PathwayBrowser/#/R-CEL-9856871 MDH1 reduces OA IEA Caenorhabditis elegans 57540 R-CEL-9861616 https://reactome.org/PathwayBrowser/#/R-CEL-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 57540 R-CEL-9861626 https://reactome.org/PathwayBrowser/#/R-CEL-9861626 SIRT4 cleaves lipoyl from DLAT IEA Caenorhabditis elegans 57540 R-CFA-109343 https://reactome.org/PathwayBrowser/#/R-CFA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Canis familiaris 57540 R-CFA-1614362 https://reactome.org/PathwayBrowser/#/R-CFA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Canis familiaris 57540 R-CFA-163217 https://reactome.org/PathwayBrowser/#/R-CFA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Canis familiaris 57540 R-CFA-173597 https://reactome.org/PathwayBrowser/#/R-CFA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Canis familiaris 57540 R-CFA-174401 https://reactome.org/PathwayBrowser/#/R-CFA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Canis familiaris 57540 R-CFA-192097 https://reactome.org/PathwayBrowser/#/R-CFA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Canis familiaris 57540 R-CFA-193073 https://reactome.org/PathwayBrowser/#/R-CFA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Canis familiaris 57540 R-CFA-193455 https://reactome.org/PathwayBrowser/#/R-CFA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 57540 R-CFA-193508 https://reactome.org/PathwayBrowser/#/R-CFA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 57540 R-CFA-193789 https://reactome.org/PathwayBrowser/#/R-CFA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Canis familiaris 57540 R-CFA-193816 https://reactome.org/PathwayBrowser/#/R-CFA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Canis familiaris 57540 R-CFA-194642 https://reactome.org/PathwayBrowser/#/R-CFA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Canis familiaris 57540 R-CFA-194718 https://reactome.org/PathwayBrowser/#/R-CFA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Canis familiaris 57540 R-CFA-196350 https://reactome.org/PathwayBrowser/#/R-CFA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Canis familiaris 57540 R-CFA-196372 https://reactome.org/PathwayBrowser/#/R-CFA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Canis familiaris 57540 R-CFA-197198 https://reactome.org/PathwayBrowser/#/R-CFA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Canis familiaris 57540 R-CFA-197271 https://reactome.org/PathwayBrowser/#/R-CFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Canis familiaris 57540 R-CFA-198824 https://reactome.org/PathwayBrowser/#/R-CFA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Canis familiaris 57540 R-CFA-2046084 https://reactome.org/PathwayBrowser/#/R-CFA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Canis familiaris 57540 R-CFA-2046089 https://reactome.org/PathwayBrowser/#/R-CFA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Canis familiaris 57540 R-CFA-2046092 https://reactome.org/PathwayBrowser/#/R-CFA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Canis familiaris 57540 R-CFA-2046096 https://reactome.org/PathwayBrowser/#/R-CFA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Canis familiaris 57540 R-CFA-2046097 https://reactome.org/PathwayBrowser/#/R-CFA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 57540 R-CFA-204617 https://reactome.org/PathwayBrowser/#/R-CFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Canis familiaris 57540 R-CFA-204647 https://reactome.org/PathwayBrowser/#/R-CFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Canis familiaris 57540 R-CFA-204662 https://reactome.org/PathwayBrowser/#/R-CFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Canis familiaris 57540 R-CFA-2161779 https://reactome.org/PathwayBrowser/#/R-CFA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Canis familiaris 57540 R-CFA-2162078 https://reactome.org/PathwayBrowser/#/R-CFA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Canis familiaris 57540 R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 57540 R-CFA-2187325 https://reactome.org/PathwayBrowser/#/R-CFA-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Canis familiaris 57540 R-CFA-2454081 https://reactome.org/PathwayBrowser/#/R-CFA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Canis familiaris 57540 R-CFA-3371467 https://reactome.org/PathwayBrowser/#/R-CFA-3371467 SIRT1 deacetylates HSF1 IEA Canis familiaris 57540 R-CFA-3640858 https://reactome.org/PathwayBrowser/#/R-CFA-3640858 Tankyrase ADP-ribosylates AXIN IEA Canis familiaris 57540 R-CFA-380608 https://reactome.org/PathwayBrowser/#/R-CFA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Canis familiaris 57540 R-CFA-389609 https://reactome.org/PathwayBrowser/#/R-CFA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Canis familiaris 57540 R-CFA-389995 https://reactome.org/PathwayBrowser/#/R-CFA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Canis familiaris 57540 R-CFA-390251 https://reactome.org/PathwayBrowser/#/R-CFA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 57540 R-CFA-427514 https://reactome.org/PathwayBrowser/#/R-CFA-427514 eNoSC deacetylates histone H3 IEA Canis familiaris 57540 R-CFA-450971 https://reactome.org/PathwayBrowser/#/R-CFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Canis familiaris 57540 R-CFA-508369 https://reactome.org/PathwayBrowser/#/R-CFA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Canis familiaris 57540 R-CFA-508473 https://reactome.org/PathwayBrowser/#/R-CFA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Canis familiaris 57540 R-CFA-5226904 https://reactome.org/PathwayBrowser/#/R-CFA-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Canis familiaris 57540 R-CFA-5362518 https://reactome.org/PathwayBrowser/#/R-CFA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Canis familiaris 57540 R-CFA-5362522 https://reactome.org/PathwayBrowser/#/R-CFA-5362522 ALDHs oxidise atRAL to atRA IEA Canis familiaris 57540 R-CFA-5362564 https://reactome.org/PathwayBrowser/#/R-CFA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Canis familiaris 57540 R-CFA-5362721 https://reactome.org/PathwayBrowser/#/R-CFA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Canis familiaris 57540 R-CFA-5651723 https://reactome.org/PathwayBrowser/#/R-CFA-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Canis familiaris 57540 R-CFA-5652195 https://reactome.org/PathwayBrowser/#/R-CFA-5652195 SORD oxidizes D-sorbitol to Fru IEA Canis familiaris 57540 R-CFA-5661290 https://reactome.org/PathwayBrowser/#/R-CFA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Canis familiaris 57540 R-CFA-5662471 https://reactome.org/PathwayBrowser/#/R-CFA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Canis familiaris 57540 R-CFA-5685953 https://reactome.org/PathwayBrowser/#/R-CFA-5685953 SIRT6 deacetylates RBBP8 IEA Canis familiaris 57540 R-CFA-5688276 https://reactome.org/PathwayBrowser/#/R-CFA-5688276 SIRT4 transfers ADPRib to GLUD IEA Canis familiaris 57540 R-CFA-5688289 https://reactome.org/PathwayBrowser/#/R-CFA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Canis familiaris 57540 R-CFA-5692237 https://reactome.org/PathwayBrowser/#/R-CFA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Canis familiaris 57540 R-CFA-5692261 https://reactome.org/PathwayBrowser/#/R-CFA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Canis familiaris 57540 R-CFA-5694018 https://reactome.org/PathwayBrowser/#/R-CFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Canis familiaris 57540 R-CFA-5696080 https://reactome.org/PathwayBrowser/#/R-CFA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Canis familiaris 57540 R-CFA-5696091 https://reactome.org/PathwayBrowser/#/R-CFA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Canis familiaris 57540 R-CFA-5696101 https://reactome.org/PathwayBrowser/#/R-CFA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Canis familiaris 57540 R-CFA-5696457 https://reactome.org/PathwayBrowser/#/R-CFA-5696457 BDH2 dehydrogenates 3HBA IEA Canis familiaris 57540 R-CFA-5696655 https://reactome.org/PathwayBrowser/#/R-CFA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Canis familiaris 57540 R-CFA-6783939 https://reactome.org/PathwayBrowser/#/R-CFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 57540 R-CFA-6784399 https://reactome.org/PathwayBrowser/#/R-CFA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Canis familiaris 57540 R-CFA-6797955 https://reactome.org/PathwayBrowser/#/R-CFA-6797955 ALDH7A1 oxidises BETALD to BET IEA Canis familiaris 57540 R-CFA-6801328 https://reactome.org/PathwayBrowser/#/R-CFA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Canis familiaris 57540 R-CFA-6806831 https://reactome.org/PathwayBrowser/#/R-CFA-6806831 CYB5Rs reduce MetHb to HbA IEA Canis familiaris 57540 R-CFA-6807826 https://reactome.org/PathwayBrowser/#/R-CFA-6807826 LDHAL6B reduces PYR to LACT IEA Canis familiaris 57540 R-CFA-6808464 https://reactome.org/PathwayBrowser/#/R-CFA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Canis familiaris 57540 R-CFA-6809264 https://reactome.org/PathwayBrowser/#/R-CFA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 57540 R-CFA-6813749 https://reactome.org/PathwayBrowser/#/R-CFA-6813749 ALDH1A1 oxidises GA to DGA IEA Canis familiaris 57540 R-CFA-70369 https://reactome.org/PathwayBrowser/#/R-CFA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Canis familiaris 57540 R-CFA-70449 https://reactome.org/PathwayBrowser/#/R-CFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Canis familiaris 57540 R-CFA-70482 https://reactome.org/PathwayBrowser/#/R-CFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Canis familiaris 57540 R-CFA-70510 https://reactome.org/PathwayBrowser/#/R-CFA-70510 LDH tetramer oxidises LACT to PYR IEA Canis familiaris 57540 R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Canis familiaris 57540 R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Canis familiaris 57540 R-CFA-70664 https://reactome.org/PathwayBrowser/#/R-CFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 57540 R-CFA-70679 https://reactome.org/PathwayBrowser/#/R-CFA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Canis familiaris 57540 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 57540 R-CFA-70837 https://reactome.org/PathwayBrowser/#/R-CFA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Canis familiaris 57540 R-CFA-70885 https://reactome.org/PathwayBrowser/#/R-CFA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Canis familiaris 57540 R-CFA-70893 https://reactome.org/PathwayBrowser/#/R-CFA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Canis familiaris 57540 R-CFA-70903 https://reactome.org/PathwayBrowser/#/R-CFA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Canis familiaris 57540 R-CFA-70940 https://reactome.org/PathwayBrowser/#/R-CFA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Canis familiaris 57540 R-CFA-70941 https://reactome.org/PathwayBrowser/#/R-CFA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Canis familiaris 57540 R-CFA-70967 https://reactome.org/PathwayBrowser/#/R-CFA-70967 IDH3 complex decarboxylates isocitrate IEA Canis familiaris 57540 R-CFA-70979 https://reactome.org/PathwayBrowser/#/R-CFA-70979 MDH2 dimer dehydrogenates MAL IEA Canis familiaris 57540 R-CFA-71037 https://reactome.org/PathwayBrowser/#/R-CFA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Canis familiaris 57540 R-CFA-71130 https://reactome.org/PathwayBrowser/#/R-CFA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Canis familiaris 57540 R-CFA-71260 https://reactome.org/PathwayBrowser/#/R-CFA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Canis familiaris 57540 R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 57540 R-CFA-71707 https://reactome.org/PathwayBrowser/#/R-CFA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Canis familiaris 57540 R-CFA-71723 https://reactome.org/PathwayBrowser/#/R-CFA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Canis familiaris 57540 R-CFA-71849 https://reactome.org/PathwayBrowser/#/R-CFA-71849 LDH tetramer reduces PYR to LACT IEA Canis familiaris 57540 R-CFA-73794 https://reactome.org/PathwayBrowser/#/R-CFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Canis familiaris 57540 R-CFA-73912 https://reactome.org/PathwayBrowser/#/R-CFA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Canis familiaris 57540 R-CFA-73920 https://reactome.org/PathwayBrowser/#/R-CFA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Canis familiaris 57540 R-CFA-75889 https://reactome.org/PathwayBrowser/#/R-CFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Canis familiaris 57540 R-CFA-77254 https://reactome.org/PathwayBrowser/#/R-CFA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Canis familiaris 57540 R-CFA-77283 https://reactome.org/PathwayBrowser/#/R-CFA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Canis familiaris 57540 R-CFA-77303 https://reactome.org/PathwayBrowser/#/R-CFA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Canis familiaris 57540 R-CFA-77312 https://reactome.org/PathwayBrowser/#/R-CFA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Canis familiaris 57540 R-CFA-77323 https://reactome.org/PathwayBrowser/#/R-CFA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Canis familiaris 57540 R-CFA-77331 https://reactome.org/PathwayBrowser/#/R-CFA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Canis familiaris 57540 R-CFA-77342 https://reactome.org/PathwayBrowser/#/R-CFA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Canis familiaris 57540 R-CFA-8870346 https://reactome.org/PathwayBrowser/#/R-CFA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Canis familiaris 57540 R-CFA-888548 https://reactome.org/PathwayBrowser/#/R-CFA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Canis familiaris 57540 R-CFA-8936442 https://reactome.org/PathwayBrowser/#/R-CFA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Canis familiaris 57540 R-CFA-8938073 https://reactome.org/PathwayBrowser/#/R-CFA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Canis familiaris 57540 R-CFA-8938076 https://reactome.org/PathwayBrowser/#/R-CFA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Canis familiaris 57540 R-CFA-8939959 https://reactome.org/PathwayBrowser/#/R-CFA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Canis familiaris 57540 R-CFA-8940070 https://reactome.org/PathwayBrowser/#/R-CFA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Canis familiaris 57540 R-CFA-8948800 https://reactome.org/PathwayBrowser/#/R-CFA-8948800 TNKS and TNKS2 PARylate PTEN IEA Canis familiaris 57540 R-CFA-8955030 https://reactome.org/PathwayBrowser/#/R-CFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Canis familiaris 57540 R-CFA-8956458 https://reactome.org/PathwayBrowser/#/R-CFA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Canis familiaris 57540 R-CFA-9012268 https://reactome.org/PathwayBrowser/#/R-CFA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Canis familiaris 57540 R-CFA-9023968 https://reactome.org/PathwayBrowser/#/R-CFA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Canis familiaris 57540 R-CFA-9024766 https://reactome.org/PathwayBrowser/#/R-CFA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Canis familiaris 57540 R-CFA-9620532 https://reactome.org/PathwayBrowser/#/R-CFA-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Canis familiaris 57540 R-CFA-9667952 https://reactome.org/PathwayBrowser/#/R-CFA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Canis familiaris 57540 R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 57540 R-CFA-9727349 https://reactome.org/PathwayBrowser/#/R-CFA-9727349 XDH dehydrogenates xanthine to form urate IEA Canis familiaris 57540 R-CFA-9748945 https://reactome.org/PathwayBrowser/#/R-CFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Canis familiaris 57540 R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 57540 R-CFA-9759549 https://reactome.org/PathwayBrowser/#/R-CFA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Canis familiaris 57540 R-CFA-977348 https://reactome.org/PathwayBrowser/#/R-CFA-977348 PHGDH tetramer dehydrogenates 3PG IEA Canis familiaris 57540 R-CFA-9853499 https://reactome.org/PathwayBrowser/#/R-CFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 57540 R-CFA-9854463 https://reactome.org/PathwayBrowser/#/R-CFA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Canis familiaris 57540 R-CFA-9856871 https://reactome.org/PathwayBrowser/#/R-CFA-9856871 MDH1 reduces OA IEA Canis familiaris 57540 R-CFA-9861616 https://reactome.org/PathwayBrowser/#/R-CFA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 57540 R-CFA-9861626 https://reactome.org/PathwayBrowser/#/R-CFA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Canis familiaris 57540 R-DDI-174401 https://reactome.org/PathwayBrowser/#/R-DDI-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Dictyostelium discoideum 57540 R-DDI-1855178 https://reactome.org/PathwayBrowser/#/R-DDI-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Dictyostelium discoideum 57540 R-DDI-193455 https://reactome.org/PathwayBrowser/#/R-DDI-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 57540 R-DDI-193508 https://reactome.org/PathwayBrowser/#/R-DDI-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 57540 R-DDI-194642 https://reactome.org/PathwayBrowser/#/R-DDI-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Dictyostelium discoideum 57540 R-DDI-194718 https://reactome.org/PathwayBrowser/#/R-DDI-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Dictyostelium discoideum 57540 R-DDI-197198 https://reactome.org/PathwayBrowser/#/R-DDI-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Dictyostelium discoideum 57540 R-DDI-197271 https://reactome.org/PathwayBrowser/#/R-DDI-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Dictyostelium discoideum 57540 R-DDI-198824 https://reactome.org/PathwayBrowser/#/R-DDI-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Dictyostelium discoideum 57540 R-DDI-204617 https://reactome.org/PathwayBrowser/#/R-DDI-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Dictyostelium discoideum 57540 R-DDI-204647 https://reactome.org/PathwayBrowser/#/R-DDI-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Dictyostelium discoideum 57540 R-DDI-204662 https://reactome.org/PathwayBrowser/#/R-DDI-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Dictyostelium discoideum 57540 R-DDI-2162078 https://reactome.org/PathwayBrowser/#/R-DDI-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Dictyostelium discoideum 57540 R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 57540 R-DDI-380608 https://reactome.org/PathwayBrowser/#/R-DDI-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Dictyostelium discoideum 57540 R-DDI-389609 https://reactome.org/PathwayBrowser/#/R-DDI-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Dictyostelium discoideum 57540 R-DDI-389995 https://reactome.org/PathwayBrowser/#/R-DDI-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Dictyostelium discoideum 57540 R-DDI-390251 https://reactome.org/PathwayBrowser/#/R-DDI-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Dictyostelium discoideum 57540 R-DDI-427514 https://reactome.org/PathwayBrowser/#/R-DDI-427514 eNoSC deacetylates histone H3 IEA Dictyostelium discoideum 57540 R-DDI-450971 https://reactome.org/PathwayBrowser/#/R-DDI-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Dictyostelium discoideum 57540 R-DDI-508369 https://reactome.org/PathwayBrowser/#/R-DDI-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Dictyostelium discoideum 57540 R-DDI-508473 https://reactome.org/PathwayBrowser/#/R-DDI-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Dictyostelium discoideum 57540 R-DDI-5362522 https://reactome.org/PathwayBrowser/#/R-DDI-5362522 ALDHs oxidise atRAL to atRA IEA Dictyostelium discoideum 57540 R-DDI-5362564 https://reactome.org/PathwayBrowser/#/R-DDI-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Dictyostelium discoideum 57540 R-DDI-5651723 https://reactome.org/PathwayBrowser/#/R-DDI-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Dictyostelium discoideum 57540 R-DDI-5688289 https://reactome.org/PathwayBrowser/#/R-DDI-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Dictyostelium discoideum 57540 R-DDI-5688294 https://reactome.org/PathwayBrowser/#/R-DDI-5688294 SIRT5 deacetylates Cytochrome C IEA Dictyostelium discoideum 57540 R-DDI-5692237 https://reactome.org/PathwayBrowser/#/R-DDI-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Dictyostelium discoideum 57540 R-DDI-5692261 https://reactome.org/PathwayBrowser/#/R-DDI-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Dictyostelium discoideum 57540 R-DDI-5694018 https://reactome.org/PathwayBrowser/#/R-DDI-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Dictyostelium discoideum 57540 R-DDI-5696080 https://reactome.org/PathwayBrowser/#/R-DDI-5696080 ALDH3B1 oxidises HXAL to PALM IEA Dictyostelium discoideum 57540 R-DDI-5696091 https://reactome.org/PathwayBrowser/#/R-DDI-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Dictyostelium discoideum 57540 R-DDI-5696101 https://reactome.org/PathwayBrowser/#/R-DDI-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Dictyostelium discoideum 57540 R-DDI-5696655 https://reactome.org/PathwayBrowser/#/R-DDI-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Dictyostelium discoideum 57540 R-DDI-6783939 https://reactome.org/PathwayBrowser/#/R-DDI-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 57540 R-DDI-6797955 https://reactome.org/PathwayBrowser/#/R-DDI-6797955 ALDH7A1 oxidises BETALD to BET IEA Dictyostelium discoideum 57540 R-DDI-6801328 https://reactome.org/PathwayBrowser/#/R-DDI-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Dictyostelium discoideum 57540 R-DDI-6808464 https://reactome.org/PathwayBrowser/#/R-DDI-6808464 ALDH3B2 oxidises HXAL to PALM IEA Dictyostelium discoideum 57540 R-DDI-6813749 https://reactome.org/PathwayBrowser/#/R-DDI-6813749 ALDH1A1 oxidises GA to DGA IEA Dictyostelium discoideum 57540 R-DDI-70369 https://reactome.org/PathwayBrowser/#/R-DDI-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Dictyostelium discoideum 57540 R-DDI-70449 https://reactome.org/PathwayBrowser/#/R-DDI-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Dictyostelium discoideum 57540 R-DDI-70482 https://reactome.org/PathwayBrowser/#/R-DDI-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Dictyostelium discoideum 57540 R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Dictyostelium discoideum 57540 R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Dictyostelium discoideum 57540 R-DDI-70664 https://reactome.org/PathwayBrowser/#/R-DDI-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 57540 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 57540 R-DDI-70837 https://reactome.org/PathwayBrowser/#/R-DDI-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Dictyostelium discoideum 57540 R-DDI-70885 https://reactome.org/PathwayBrowser/#/R-DDI-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Dictyostelium discoideum 57540 R-DDI-70893 https://reactome.org/PathwayBrowser/#/R-DDI-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 57540 R-DDI-70903 https://reactome.org/PathwayBrowser/#/R-DDI-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Dictyostelium discoideum 57540 R-DDI-70940 https://reactome.org/PathwayBrowser/#/R-DDI-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Dictyostelium discoideum 57540 R-DDI-70941 https://reactome.org/PathwayBrowser/#/R-DDI-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Dictyostelium discoideum 57540 R-DDI-70967 https://reactome.org/PathwayBrowser/#/R-DDI-70967 IDH3 complex decarboxylates isocitrate IEA Dictyostelium discoideum 57540 R-DDI-71037 https://reactome.org/PathwayBrowser/#/R-DDI-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 57540 R-DDI-71130 https://reactome.org/PathwayBrowser/#/R-DDI-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Dictyostelium discoideum 57540 R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 57540 R-DDI-71707 https://reactome.org/PathwayBrowser/#/R-DDI-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Dictyostelium discoideum 57540 R-DDI-71723 https://reactome.org/PathwayBrowser/#/R-DDI-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Dictyostelium discoideum 57540 R-DDI-73794 https://reactome.org/PathwayBrowser/#/R-DDI-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Dictyostelium discoideum 57540 R-DDI-8936442 https://reactome.org/PathwayBrowser/#/R-DDI-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Dictyostelium discoideum 57540 R-DDI-8938073 https://reactome.org/PathwayBrowser/#/R-DDI-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Dictyostelium discoideum 57540 R-DDI-8939959 https://reactome.org/PathwayBrowser/#/R-DDI-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Dictyostelium discoideum 57540 R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 57540 R-DDI-9727349 https://reactome.org/PathwayBrowser/#/R-DDI-9727349 XDH dehydrogenates xanthine to form urate IEA Dictyostelium discoideum 57540 R-DDI-9748945 https://reactome.org/PathwayBrowser/#/R-DDI-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Dictyostelium discoideum 57540 R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 57540 R-DDI-9759549 https://reactome.org/PathwayBrowser/#/R-DDI-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Dictyostelium discoideum 57540 R-DDI-9853499 https://reactome.org/PathwayBrowser/#/R-DDI-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 57540 R-DDI-9856871 https://reactome.org/PathwayBrowser/#/R-DDI-9856871 MDH1 reduces OA IEA Dictyostelium discoideum 57540 R-DDI-9861616 https://reactome.org/PathwayBrowser/#/R-DDI-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 57540 R-DME-163217 https://reactome.org/PathwayBrowser/#/R-DME-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Drosophila melanogaster 57540 R-DME-173597 https://reactome.org/PathwayBrowser/#/R-DME-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Drosophila melanogaster 57540 R-DME-174401 https://reactome.org/PathwayBrowser/#/R-DME-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Drosophila melanogaster 57540 R-DME-1855178 https://reactome.org/PathwayBrowser/#/R-DME-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Drosophila melanogaster 57540 R-DME-193455 https://reactome.org/PathwayBrowser/#/R-DME-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 57540 R-DME-193508 https://reactome.org/PathwayBrowser/#/R-DME-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 57540 R-DME-197198 https://reactome.org/PathwayBrowser/#/R-DME-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 57540 R-DME-197271 https://reactome.org/PathwayBrowser/#/R-DME-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Drosophila melanogaster 57540 R-DME-198824 https://reactome.org/PathwayBrowser/#/R-DME-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Drosophila melanogaster 57540 R-DME-204617 https://reactome.org/PathwayBrowser/#/R-DME-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Drosophila melanogaster 57540 R-DME-204647 https://reactome.org/PathwayBrowser/#/R-DME-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Drosophila melanogaster 57540 R-DME-204662 https://reactome.org/PathwayBrowser/#/R-DME-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Drosophila melanogaster 57540 R-DME-2161779 https://reactome.org/PathwayBrowser/#/R-DME-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Drosophila melanogaster 57540 R-DME-2162078 https://reactome.org/PathwayBrowser/#/R-DME-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Drosophila melanogaster 57540 R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 57540 R-DME-2187325 https://reactome.org/PathwayBrowser/#/R-DME-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Drosophila melanogaster 57540 R-DME-380608 https://reactome.org/PathwayBrowser/#/R-DME-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Drosophila melanogaster 57540 R-DME-389609 https://reactome.org/PathwayBrowser/#/R-DME-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Drosophila melanogaster 57540 R-DME-389995 https://reactome.org/PathwayBrowser/#/R-DME-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Drosophila melanogaster 57540 R-DME-390251 https://reactome.org/PathwayBrowser/#/R-DME-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Drosophila melanogaster 57540 R-DME-427514 https://reactome.org/PathwayBrowser/#/R-DME-427514 eNoSC deacetylates histone H3 IEA Drosophila melanogaster 57540 R-DME-508369 https://reactome.org/PathwayBrowser/#/R-DME-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Drosophila melanogaster 57540 R-DME-508473 https://reactome.org/PathwayBrowser/#/R-DME-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Drosophila melanogaster 57540 R-DME-5226904 https://reactome.org/PathwayBrowser/#/R-DME-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Drosophila melanogaster 57540 R-DME-5362518 https://reactome.org/PathwayBrowser/#/R-DME-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Drosophila melanogaster 57540 R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster 57540 R-DME-5362564 https://reactome.org/PathwayBrowser/#/R-DME-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Drosophila melanogaster 57540 R-DME-5362721 https://reactome.org/PathwayBrowser/#/R-DME-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 57540 R-DME-5652195 https://reactome.org/PathwayBrowser/#/R-DME-5652195 SORD oxidizes D-sorbitol to Fru IEA Drosophila melanogaster 57540 R-DME-5661290 https://reactome.org/PathwayBrowser/#/R-DME-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Drosophila melanogaster 57540 R-DME-5662471 https://reactome.org/PathwayBrowser/#/R-DME-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Drosophila melanogaster 57540 R-DME-5687653 https://reactome.org/PathwayBrowser/#/R-DME-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Drosophila melanogaster 57540 R-DME-5688276 https://reactome.org/PathwayBrowser/#/R-DME-5688276 SIRT4 transfers ADPRib to GLUD IEA Drosophila melanogaster 57540 R-DME-5692237 https://reactome.org/PathwayBrowser/#/R-DME-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Drosophila melanogaster 57540 R-DME-5692261 https://reactome.org/PathwayBrowser/#/R-DME-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Drosophila melanogaster 57540 R-DME-5694018 https://reactome.org/PathwayBrowser/#/R-DME-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Drosophila melanogaster 57540 R-DME-5696080 https://reactome.org/PathwayBrowser/#/R-DME-5696080 ALDH3B1 oxidises HXAL to PALM IEA Drosophila melanogaster 57540 R-DME-5696091 https://reactome.org/PathwayBrowser/#/R-DME-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Drosophila melanogaster 57540 R-DME-5696655 https://reactome.org/PathwayBrowser/#/R-DME-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Drosophila melanogaster 57540 R-DME-6783939 https://reactome.org/PathwayBrowser/#/R-DME-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 57540 R-DME-6797955 https://reactome.org/PathwayBrowser/#/R-DME-6797955 ALDH7A1 oxidises BETALD to BET IEA Drosophila melanogaster 57540 R-DME-6801328 https://reactome.org/PathwayBrowser/#/R-DME-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Drosophila melanogaster 57540 R-DME-6807826 https://reactome.org/PathwayBrowser/#/R-DME-6807826 LDHAL6B reduces PYR to LACT IEA Drosophila melanogaster 57540 R-DME-6808464 https://reactome.org/PathwayBrowser/#/R-DME-6808464 ALDH3B2 oxidises HXAL to PALM IEA Drosophila melanogaster 57540 R-DME-6813749 https://reactome.org/PathwayBrowser/#/R-DME-6813749 ALDH1A1 oxidises GA to DGA IEA Drosophila melanogaster 57540 R-DME-70369 https://reactome.org/PathwayBrowser/#/R-DME-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Drosophila melanogaster 57540 R-DME-70449 https://reactome.org/PathwayBrowser/#/R-DME-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Drosophila melanogaster 57540 R-DME-70482 https://reactome.org/PathwayBrowser/#/R-DME-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Drosophila melanogaster 57540 R-DME-70510 https://reactome.org/PathwayBrowser/#/R-DME-70510 LDH tetramer oxidises LACT to PYR IEA Drosophila melanogaster 57540 R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Drosophila melanogaster 57540 R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Drosophila melanogaster 57540 R-DME-70664 https://reactome.org/PathwayBrowser/#/R-DME-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 57540 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 57540 R-DME-70837 https://reactome.org/PathwayBrowser/#/R-DME-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Drosophila melanogaster 57540 R-DME-70885 https://reactome.org/PathwayBrowser/#/R-DME-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Drosophila melanogaster 57540 R-DME-70893 https://reactome.org/PathwayBrowser/#/R-DME-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 57540 R-DME-70940 https://reactome.org/PathwayBrowser/#/R-DME-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Drosophila melanogaster 57540 R-DME-70941 https://reactome.org/PathwayBrowser/#/R-DME-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Drosophila melanogaster 57540 R-DME-70967 https://reactome.org/PathwayBrowser/#/R-DME-70967 IDH3 complex decarboxylates isocitrate IEA Drosophila melanogaster 57540 R-DME-70979 https://reactome.org/PathwayBrowser/#/R-DME-70979 MDH2 dimer dehydrogenates MAL IEA Drosophila melanogaster 57540 R-DME-71037 https://reactome.org/PathwayBrowser/#/R-DME-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 57540 R-DME-71130 https://reactome.org/PathwayBrowser/#/R-DME-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Drosophila melanogaster 57540 R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 57540 R-DME-71707 https://reactome.org/PathwayBrowser/#/R-DME-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Drosophila melanogaster 57540 R-DME-71723 https://reactome.org/PathwayBrowser/#/R-DME-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Drosophila melanogaster 57540 R-DME-71849 https://reactome.org/PathwayBrowser/#/R-DME-71849 LDH tetramer reduces PYR to LACT IEA Drosophila melanogaster 57540 R-DME-73794 https://reactome.org/PathwayBrowser/#/R-DME-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Drosophila melanogaster 57540 R-DME-73912 https://reactome.org/PathwayBrowser/#/R-DME-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Drosophila melanogaster 57540 R-DME-73920 https://reactome.org/PathwayBrowser/#/R-DME-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Drosophila melanogaster 57540 R-DME-75889 https://reactome.org/PathwayBrowser/#/R-DME-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Drosophila melanogaster 57540 R-DME-77283 https://reactome.org/PathwayBrowser/#/R-DME-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Drosophila melanogaster 57540 R-DME-77303 https://reactome.org/PathwayBrowser/#/R-DME-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Drosophila melanogaster 57540 R-DME-888548 https://reactome.org/PathwayBrowser/#/R-DME-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Drosophila melanogaster 57540 R-DME-8936442 https://reactome.org/PathwayBrowser/#/R-DME-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Drosophila melanogaster 57540 R-DME-8938073 https://reactome.org/PathwayBrowser/#/R-DME-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Drosophila melanogaster 57540 R-DME-8939959 https://reactome.org/PathwayBrowser/#/R-DME-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Drosophila melanogaster 57540 R-DME-8940070 https://reactome.org/PathwayBrowser/#/R-DME-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Drosophila melanogaster 57540 R-DME-8955030 https://reactome.org/PathwayBrowser/#/R-DME-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 57540 R-DME-9012268 https://reactome.org/PathwayBrowser/#/R-DME-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 57540 R-DME-9023968 https://reactome.org/PathwayBrowser/#/R-DME-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Drosophila melanogaster 57540 R-DME-9024766 https://reactome.org/PathwayBrowser/#/R-DME-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Drosophila melanogaster 57540 R-DME-9620532 https://reactome.org/PathwayBrowser/#/R-DME-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Drosophila melanogaster 57540 R-DME-9667952 https://reactome.org/PathwayBrowser/#/R-DME-9667952 ANKLE2 is deacetylated by SIRT2 IEA Drosophila melanogaster 57540 R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 57540 R-DME-9727349 https://reactome.org/PathwayBrowser/#/R-DME-9727349 XDH dehydrogenates xanthine to form urate IEA Drosophila melanogaster 57540 R-DME-9748945 https://reactome.org/PathwayBrowser/#/R-DME-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Drosophila melanogaster 57540 R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 57540 R-DME-977348 https://reactome.org/PathwayBrowser/#/R-DME-977348 PHGDH tetramer dehydrogenates 3PG IEA Drosophila melanogaster 57540 R-DME-9853499 https://reactome.org/PathwayBrowser/#/R-DME-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 57540 R-DME-9856871 https://reactome.org/PathwayBrowser/#/R-DME-9856871 MDH1 reduces OA IEA Drosophila melanogaster 57540 R-DME-9861616 https://reactome.org/PathwayBrowser/#/R-DME-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 57540 R-DME-9861626 https://reactome.org/PathwayBrowser/#/R-DME-9861626 SIRT4 cleaves lipoyl from DLAT IEA Drosophila melanogaster 57540 R-DRE-163217 https://reactome.org/PathwayBrowser/#/R-DRE-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Danio rerio 57540 R-DRE-173597 https://reactome.org/PathwayBrowser/#/R-DRE-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Danio rerio 57540 R-DRE-174401 https://reactome.org/PathwayBrowser/#/R-DRE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Danio rerio 57540 R-DRE-192097 https://reactome.org/PathwayBrowser/#/R-DRE-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Danio rerio 57540 R-DRE-193073 https://reactome.org/PathwayBrowser/#/R-DRE-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Danio rerio 57540 R-DRE-193789 https://reactome.org/PathwayBrowser/#/R-DRE-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Danio rerio 57540 R-DRE-193816 https://reactome.org/PathwayBrowser/#/R-DRE-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Danio rerio 57540 R-DRE-194642 https://reactome.org/PathwayBrowser/#/R-DRE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Danio rerio 57540 R-DRE-194718 https://reactome.org/PathwayBrowser/#/R-DRE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Danio rerio 57540 R-DRE-196350 https://reactome.org/PathwayBrowser/#/R-DRE-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Danio rerio 57540 R-DRE-196372 https://reactome.org/PathwayBrowser/#/R-DRE-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Danio rerio 57540 R-DRE-197198 https://reactome.org/PathwayBrowser/#/R-DRE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Danio rerio 57540 R-DRE-197271 https://reactome.org/PathwayBrowser/#/R-DRE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Danio rerio 57540 R-DRE-198824 https://reactome.org/PathwayBrowser/#/R-DRE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Danio rerio 57540 R-DRE-2046084 https://reactome.org/PathwayBrowser/#/R-DRE-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Danio rerio 57540 R-DRE-2046096 https://reactome.org/PathwayBrowser/#/R-DRE-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Danio rerio 57540 R-DRE-2046097 https://reactome.org/PathwayBrowser/#/R-DRE-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 57540 R-DRE-204617 https://reactome.org/PathwayBrowser/#/R-DRE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Danio rerio 57540 R-DRE-204647 https://reactome.org/PathwayBrowser/#/R-DRE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Danio rerio 57540 R-DRE-204662 https://reactome.org/PathwayBrowser/#/R-DRE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Danio rerio 57540 R-DRE-2161779 https://reactome.org/PathwayBrowser/#/R-DRE-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Danio rerio 57540 R-DRE-2162078 https://reactome.org/PathwayBrowser/#/R-DRE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Danio rerio 57540 R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 57540 R-DRE-2454081 https://reactome.org/PathwayBrowser/#/R-DRE-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Danio rerio 57540 R-DRE-380608 https://reactome.org/PathwayBrowser/#/R-DRE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Danio rerio 57540 R-DRE-389609 https://reactome.org/PathwayBrowser/#/R-DRE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Danio rerio 57540 R-DRE-450971 https://reactome.org/PathwayBrowser/#/R-DRE-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Danio rerio 57540 R-DRE-508369 https://reactome.org/PathwayBrowser/#/R-DRE-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Danio rerio 57540 R-DRE-508473 https://reactome.org/PathwayBrowser/#/R-DRE-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Danio rerio 57540 R-DRE-5362518 https://reactome.org/PathwayBrowser/#/R-DRE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Danio rerio 57540 R-DRE-5362522 https://reactome.org/PathwayBrowser/#/R-DRE-5362522 ALDHs oxidise atRAL to atRA IEA Danio rerio 57540 R-DRE-5362564 https://reactome.org/PathwayBrowser/#/R-DRE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Danio rerio 57540 R-DRE-5362721 https://reactome.org/PathwayBrowser/#/R-DRE-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Danio rerio 57540 R-DRE-5651723 https://reactome.org/PathwayBrowser/#/R-DRE-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Danio rerio 57540 R-DRE-5661290 https://reactome.org/PathwayBrowser/#/R-DRE-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Danio rerio 57540 R-DRE-5685953 https://reactome.org/PathwayBrowser/#/R-DRE-5685953 SIRT6 deacetylates RBBP8 IEA Danio rerio 57540 R-DRE-5688276 https://reactome.org/PathwayBrowser/#/R-DRE-5688276 SIRT4 transfers ADPRib to GLUD IEA Danio rerio 57540 R-DRE-5688294 https://reactome.org/PathwayBrowser/#/R-DRE-5688294 SIRT5 deacetylates Cytochrome C IEA Danio rerio 57540 R-DRE-5692237 https://reactome.org/PathwayBrowser/#/R-DRE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Danio rerio 57540 R-DRE-5692261 https://reactome.org/PathwayBrowser/#/R-DRE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Danio rerio 57540 R-DRE-5694018 https://reactome.org/PathwayBrowser/#/R-DRE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Danio rerio 57540 R-DRE-5696080 https://reactome.org/PathwayBrowser/#/R-DRE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Danio rerio 57540 R-DRE-5696091 https://reactome.org/PathwayBrowser/#/R-DRE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Danio rerio 57540 R-DRE-5696101 https://reactome.org/PathwayBrowser/#/R-DRE-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Danio rerio 57540 R-DRE-5696457 https://reactome.org/PathwayBrowser/#/R-DRE-5696457 BDH2 dehydrogenates 3HBA IEA Danio rerio 57540 R-DRE-5696655 https://reactome.org/PathwayBrowser/#/R-DRE-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Danio rerio 57540 R-DRE-6783939 https://reactome.org/PathwayBrowser/#/R-DRE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 57540 R-DRE-6784399 https://reactome.org/PathwayBrowser/#/R-DRE-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Danio rerio 57540 R-DRE-6797955 https://reactome.org/PathwayBrowser/#/R-DRE-6797955 ALDH7A1 oxidises BETALD to BET IEA Danio rerio 57540 R-DRE-6801328 https://reactome.org/PathwayBrowser/#/R-DRE-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Danio rerio 57540 R-DRE-6806831 https://reactome.org/PathwayBrowser/#/R-DRE-6806831 CYB5Rs reduce MetHb to HbA IEA Danio rerio 57540 R-DRE-6807826 https://reactome.org/PathwayBrowser/#/R-DRE-6807826 LDHAL6B reduces PYR to LACT IEA Danio rerio 57540 R-DRE-6808464 https://reactome.org/PathwayBrowser/#/R-DRE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Danio rerio 57540 R-DRE-6809264 https://reactome.org/PathwayBrowser/#/R-DRE-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Danio rerio 57540 R-DRE-70369 https://reactome.org/PathwayBrowser/#/R-DRE-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Danio rerio 57540 R-DRE-70449 https://reactome.org/PathwayBrowser/#/R-DRE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Danio rerio 57540 R-DRE-70482 https://reactome.org/PathwayBrowser/#/R-DRE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Danio rerio 57540 R-DRE-70510 https://reactome.org/PathwayBrowser/#/R-DRE-70510 LDH tetramer oxidises LACT to PYR IEA Danio rerio 57540 R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Danio rerio 57540 R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Danio rerio 57540 R-DRE-70664 https://reactome.org/PathwayBrowser/#/R-DRE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 57540 R-DRE-70679 https://reactome.org/PathwayBrowser/#/R-DRE-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Danio rerio 57540 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 57540 R-DRE-70837 https://reactome.org/PathwayBrowser/#/R-DRE-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Danio rerio 57540 R-DRE-70885 https://reactome.org/PathwayBrowser/#/R-DRE-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Danio rerio 57540 R-DRE-70893 https://reactome.org/PathwayBrowser/#/R-DRE-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Danio rerio 57540 R-DRE-70903 https://reactome.org/PathwayBrowser/#/R-DRE-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Danio rerio 57540 R-DRE-70940 https://reactome.org/PathwayBrowser/#/R-DRE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Danio rerio 57540 R-DRE-70941 https://reactome.org/PathwayBrowser/#/R-DRE-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Danio rerio 57540 R-DRE-70979 https://reactome.org/PathwayBrowser/#/R-DRE-70979 MDH2 dimer dehydrogenates MAL IEA Danio rerio 57540 R-DRE-71037 https://reactome.org/PathwayBrowser/#/R-DRE-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Danio rerio 57540 R-DRE-71130 https://reactome.org/PathwayBrowser/#/R-DRE-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Danio rerio 57540 R-DRE-71260 https://reactome.org/PathwayBrowser/#/R-DRE-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Danio rerio 57540 R-DRE-71707 https://reactome.org/PathwayBrowser/#/R-DRE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Danio rerio 57540 R-DRE-71723 https://reactome.org/PathwayBrowser/#/R-DRE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Danio rerio 57540 R-DRE-71849 https://reactome.org/PathwayBrowser/#/R-DRE-71849 LDH tetramer reduces PYR to LACT IEA Danio rerio 57540 R-DRE-73794 https://reactome.org/PathwayBrowser/#/R-DRE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Danio rerio 57540 R-DRE-73912 https://reactome.org/PathwayBrowser/#/R-DRE-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Danio rerio 57540 R-DRE-73920 https://reactome.org/PathwayBrowser/#/R-DRE-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Danio rerio 57540 R-DRE-75889 https://reactome.org/PathwayBrowser/#/R-DRE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Danio rerio 57540 R-DRE-77254 https://reactome.org/PathwayBrowser/#/R-DRE-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Danio rerio 57540 R-DRE-77283 https://reactome.org/PathwayBrowser/#/R-DRE-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Danio rerio 57540 R-DRE-77303 https://reactome.org/PathwayBrowser/#/R-DRE-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Danio rerio 57540 R-DRE-77312 https://reactome.org/PathwayBrowser/#/R-DRE-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Danio rerio 57540 R-DRE-77323 https://reactome.org/PathwayBrowser/#/R-DRE-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Danio rerio 57540 R-DRE-77331 https://reactome.org/PathwayBrowser/#/R-DRE-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Danio rerio 57540 R-DRE-77342 https://reactome.org/PathwayBrowser/#/R-DRE-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Danio rerio 57540 R-DRE-8936442 https://reactome.org/PathwayBrowser/#/R-DRE-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Danio rerio 57540 R-DRE-8938073 https://reactome.org/PathwayBrowser/#/R-DRE-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Danio rerio 57540 R-DRE-8939959 https://reactome.org/PathwayBrowser/#/R-DRE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Danio rerio 57540 R-DRE-8940070 https://reactome.org/PathwayBrowser/#/R-DRE-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Danio rerio 57540 R-DRE-8956458 https://reactome.org/PathwayBrowser/#/R-DRE-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Danio rerio 57540 R-DRE-9012268 https://reactome.org/PathwayBrowser/#/R-DRE-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Danio rerio 57540 R-DRE-9023968 https://reactome.org/PathwayBrowser/#/R-DRE-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Danio rerio 57540 R-DRE-9024766 https://reactome.org/PathwayBrowser/#/R-DRE-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Danio rerio 57540 R-DRE-9667952 https://reactome.org/PathwayBrowser/#/R-DRE-9667952 ANKLE2 is deacetylated by SIRT2 IEA Danio rerio 57540 R-DRE-9748945 https://reactome.org/PathwayBrowser/#/R-DRE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Danio rerio 57540 R-DRE-9759549 https://reactome.org/PathwayBrowser/#/R-DRE-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Danio rerio 57540 R-DRE-9853499 https://reactome.org/PathwayBrowser/#/R-DRE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Danio rerio 57540 R-DRE-9856871 https://reactome.org/PathwayBrowser/#/R-DRE-9856871 MDH1 reduces OA IEA Danio rerio 57540 R-DRE-9861626 https://reactome.org/PathwayBrowser/#/R-DRE-9861626 SIRT4 cleaves lipoyl from DLAT IEA Danio rerio 57540 R-FCA-164926 https://reactome.org/PathwayBrowser/#/R-FCA-164926 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ TAS Felis catus 57540 R-GGA-109343 https://reactome.org/PathwayBrowser/#/R-GGA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Gallus gallus 57540 R-GGA-1614362 https://reactome.org/PathwayBrowser/#/R-GGA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Gallus gallus 57540 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Gallus gallus 57540 R-GGA-173597 https://reactome.org/PathwayBrowser/#/R-GGA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Gallus gallus 57540 R-GGA-174401 https://reactome.org/PathwayBrowser/#/R-GGA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Gallus gallus 57540 R-GGA-1855178 https://reactome.org/PathwayBrowser/#/R-GGA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Gallus gallus 57540 R-GGA-193073 https://reactome.org/PathwayBrowser/#/R-GGA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Gallus gallus 57540 R-GGA-193455 https://reactome.org/PathwayBrowser/#/R-GGA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 57540 R-GGA-193508 https://reactome.org/PathwayBrowser/#/R-GGA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 57540 R-GGA-194642 https://reactome.org/PathwayBrowser/#/R-GGA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Gallus gallus 57540 R-GGA-194718 https://reactome.org/PathwayBrowser/#/R-GGA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Gallus gallus 57540 R-GGA-196350 https://reactome.org/PathwayBrowser/#/R-GGA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Gallus gallus 57540 R-GGA-196372 https://reactome.org/PathwayBrowser/#/R-GGA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Gallus gallus 57540 R-GGA-197198 https://reactome.org/PathwayBrowser/#/R-GGA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Gallus gallus 57540 R-GGA-197271 https://reactome.org/PathwayBrowser/#/R-GGA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Gallus gallus 57540 R-GGA-198824 https://reactome.org/PathwayBrowser/#/R-GGA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Gallus gallus 57540 R-GGA-2046084 https://reactome.org/PathwayBrowser/#/R-GGA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Gallus gallus 57540 R-GGA-2046089 https://reactome.org/PathwayBrowser/#/R-GGA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Gallus gallus 57540 R-GGA-2046092 https://reactome.org/PathwayBrowser/#/R-GGA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Gallus gallus 57540 R-GGA-2046096 https://reactome.org/PathwayBrowser/#/R-GGA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Gallus gallus 57540 R-GGA-2046097 https://reactome.org/PathwayBrowser/#/R-GGA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 57540 R-GGA-204662 https://reactome.org/PathwayBrowser/#/R-GGA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Gallus gallus 57540 R-GGA-2161779 https://reactome.org/PathwayBrowser/#/R-GGA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Gallus gallus 57540 R-GGA-2162078 https://reactome.org/PathwayBrowser/#/R-GGA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Gallus gallus 57540 R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 57540 R-GGA-2454081 https://reactome.org/PathwayBrowser/#/R-GGA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Gallus gallus 57540 R-GGA-3371467 https://reactome.org/PathwayBrowser/#/R-GGA-3371467 SIRT1 deacetylates HSF1 IEA Gallus gallus 57540 R-GGA-352921 https://reactome.org/PathwayBrowser/#/R-GGA-352921 1,3-bisphosphoglycerate + NADH + H+ <=> glyceraldehyde 3-phosphate + NAD+ + phosphate TAS Gallus gallus 57540 R-GGA-352956 https://reactome.org/PathwayBrowser/#/R-GGA-352956 glyceraldehyde 3-phosphate + NAD+ + phosphate <=> 1,3-bisphosphoglycerate + NADH + H+ TAS Gallus gallus 57540 R-GGA-3640858 https://reactome.org/PathwayBrowser/#/R-GGA-3640858 Tankyrase ADP-ribosylates AXIN IEA Gallus gallus 57540 R-GGA-372422 https://reactome.org/PathwayBrowser/#/R-GGA-372422 oxaloacetate + NADH + H+ <=> malate + NAD+ TAS Gallus gallus 57540 R-GGA-372855 https://reactome.org/PathwayBrowser/#/R-GGA-372855 malate + NAD+ <=> oxaloacetate + NADH + H+ TAS Gallus gallus 57540 R-GGA-372903 https://reactome.org/PathwayBrowser/#/R-GGA-372903 lactate + NAD+ <=> pyruvate + NADH + H+ TAS Gallus gallus 57540 R-GGA-372910 https://reactome.org/PathwayBrowser/#/R-GGA-372910 pyruvate + NADH + H+ <=> lactate + NAD+ TAS Gallus gallus 57540 R-GGA-373024 https://reactome.org/PathwayBrowser/#/R-GGA-373024 isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ IEA Gallus gallus 57540 R-GGA-373042 https://reactome.org/PathwayBrowser/#/R-GGA-373042 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ IEA Gallus gallus 57540 R-GGA-373047 https://reactome.org/PathwayBrowser/#/R-GGA-373047 malate + NAD+ <=> oxaloacetate + NADH + H+ IEA Gallus gallus 57540 R-GGA-373177 https://reactome.org/PathwayBrowser/#/R-GGA-373177 pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ TAS Gallus gallus 57540 R-GGA-380608 https://reactome.org/PathwayBrowser/#/R-GGA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Gallus gallus 57540 R-GGA-389609 https://reactome.org/PathwayBrowser/#/R-GGA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Gallus gallus 57540 R-GGA-389995 https://reactome.org/PathwayBrowser/#/R-GGA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Gallus gallus 57540 R-GGA-390251 https://reactome.org/PathwayBrowser/#/R-GGA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 57540 R-GGA-421158 https://reactome.org/PathwayBrowser/#/R-GGA-421158 xanthine + H2O + NAD+ => urate + NADH + H+ TAS Gallus gallus 57540 R-GGA-421161 https://reactome.org/PathwayBrowser/#/R-GGA-421161 hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ TAS Gallus gallus 57540 R-GGA-421222 https://reactome.org/PathwayBrowser/#/R-GGA-421222 inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ IEA Gallus gallus 57540 R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 57540 R-GGA-450971 https://reactome.org/PathwayBrowser/#/R-GGA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Gallus gallus 57540 R-GGA-508369 https://reactome.org/PathwayBrowser/#/R-GGA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Gallus gallus 57540 R-GGA-508473 https://reactome.org/PathwayBrowser/#/R-GGA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Gallus gallus 57540 R-GGA-5226904 https://reactome.org/PathwayBrowser/#/R-GGA-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Gallus gallus 57540 R-GGA-5362518 https://reactome.org/PathwayBrowser/#/R-GGA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Gallus gallus 57540 R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus 57540 R-GGA-5362564 https://reactome.org/PathwayBrowser/#/R-GGA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Gallus gallus 57540 R-GGA-5362721 https://reactome.org/PathwayBrowser/#/R-GGA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Gallus gallus 57540 R-GGA-5652195 https://reactome.org/PathwayBrowser/#/R-GGA-5652195 SORD oxidizes D-sorbitol to Fru IEA Gallus gallus 57540 R-GGA-5661290 https://reactome.org/PathwayBrowser/#/R-GGA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Gallus gallus 57540 R-GGA-5662471 https://reactome.org/PathwayBrowser/#/R-GGA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Gallus gallus 57540 R-GGA-5685953 https://reactome.org/PathwayBrowser/#/R-GGA-5685953 SIRT6 deacetylates RBBP8 IEA Gallus gallus 57540 R-GGA-5687653 https://reactome.org/PathwayBrowser/#/R-GGA-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Gallus gallus 57540 R-GGA-5688276 https://reactome.org/PathwayBrowser/#/R-GGA-5688276 SIRT4 transfers ADPRib to GLUD IEA Gallus gallus 57540 R-GGA-5688289 https://reactome.org/PathwayBrowser/#/R-GGA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Gallus gallus 57540 R-GGA-5688294 https://reactome.org/PathwayBrowser/#/R-GGA-5688294 SIRT5 deacetylates Cytochrome C IEA Gallus gallus 57540 R-GGA-5692237 https://reactome.org/PathwayBrowser/#/R-GGA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Gallus gallus 57540 R-GGA-5692261 https://reactome.org/PathwayBrowser/#/R-GGA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Gallus gallus 57540 R-GGA-5694018 https://reactome.org/PathwayBrowser/#/R-GGA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Gallus gallus 57540 R-GGA-5696080 https://reactome.org/PathwayBrowser/#/R-GGA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Gallus gallus 57540 R-GGA-5696101 https://reactome.org/PathwayBrowser/#/R-GGA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Gallus gallus 57540 R-GGA-5696457 https://reactome.org/PathwayBrowser/#/R-GGA-5696457 BDH2 dehydrogenates 3HBA IEA Gallus gallus 57540 R-GGA-5696655 https://reactome.org/PathwayBrowser/#/R-GGA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Gallus gallus 57540 R-GGA-6783939 https://reactome.org/PathwayBrowser/#/R-GGA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 57540 R-GGA-6784399 https://reactome.org/PathwayBrowser/#/R-GGA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Gallus gallus 57540 R-GGA-6797955 https://reactome.org/PathwayBrowser/#/R-GGA-6797955 ALDH7A1 oxidises BETALD to BET IEA Gallus gallus 57540 R-GGA-6801328 https://reactome.org/PathwayBrowser/#/R-GGA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Gallus gallus 57540 R-GGA-6806831 https://reactome.org/PathwayBrowser/#/R-GGA-6806831 CYB5Rs reduce MetHb to HbA IEA Gallus gallus 57540 R-GGA-6807826 https://reactome.org/PathwayBrowser/#/R-GGA-6807826 LDHAL6B reduces PYR to LACT IEA Gallus gallus 57540 R-GGA-6808464 https://reactome.org/PathwayBrowser/#/R-GGA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Gallus gallus 57540 R-GGA-6809264 https://reactome.org/PathwayBrowser/#/R-GGA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 57540 R-GGA-6813749 https://reactome.org/PathwayBrowser/#/R-GGA-6813749 ALDH1A1 oxidises GA to DGA IEA Gallus gallus 57540 R-GGA-70369 https://reactome.org/PathwayBrowser/#/R-GGA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Gallus gallus 57540 R-GGA-70449 https://reactome.org/PathwayBrowser/#/R-GGA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Gallus gallus 57540 R-GGA-70482 https://reactome.org/PathwayBrowser/#/R-GGA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Gallus gallus 57540 R-GGA-70510 https://reactome.org/PathwayBrowser/#/R-GGA-70510 LDH tetramer oxidises LACT to PYR IEA Gallus gallus 57540 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Gallus gallus 57540 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Gallus gallus 57540 R-GGA-70664 https://reactome.org/PathwayBrowser/#/R-GGA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 57540 R-GGA-70679 https://reactome.org/PathwayBrowser/#/R-GGA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Gallus gallus 57540 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 57540 R-GGA-70837 https://reactome.org/PathwayBrowser/#/R-GGA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Gallus gallus 57540 R-GGA-70885 https://reactome.org/PathwayBrowser/#/R-GGA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Gallus gallus 57540 R-GGA-70893 https://reactome.org/PathwayBrowser/#/R-GGA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Gallus gallus 57540 R-GGA-70903 https://reactome.org/PathwayBrowser/#/R-GGA-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Gallus gallus 57540 R-GGA-70940 https://reactome.org/PathwayBrowser/#/R-GGA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Gallus gallus 57540 R-GGA-70941 https://reactome.org/PathwayBrowser/#/R-GGA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Gallus gallus 57540 R-GGA-70979 https://reactome.org/PathwayBrowser/#/R-GGA-70979 MDH2 dimer dehydrogenates MAL IEA Gallus gallus 57540 R-GGA-71037 https://reactome.org/PathwayBrowser/#/R-GGA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Gallus gallus 57540 R-GGA-71130 https://reactome.org/PathwayBrowser/#/R-GGA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Gallus gallus 57540 R-GGA-71260 https://reactome.org/PathwayBrowser/#/R-GGA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Gallus gallus 57540 R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 57540 R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus 57540 R-GGA-71723 https://reactome.org/PathwayBrowser/#/R-GGA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Gallus gallus 57540 R-GGA-71849 https://reactome.org/PathwayBrowser/#/R-GGA-71849 LDH tetramer reduces PYR to LACT IEA Gallus gallus 57540 R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus 57540 R-GGA-73912 https://reactome.org/PathwayBrowser/#/R-GGA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Gallus gallus 57540 R-GGA-73920 https://reactome.org/PathwayBrowser/#/R-GGA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Gallus gallus 57540 R-GGA-75889 https://reactome.org/PathwayBrowser/#/R-GGA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Gallus gallus 57540 R-GGA-77254 https://reactome.org/PathwayBrowser/#/R-GGA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Gallus gallus 57540 R-GGA-77283 https://reactome.org/PathwayBrowser/#/R-GGA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Gallus gallus 57540 R-GGA-77303 https://reactome.org/PathwayBrowser/#/R-GGA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Gallus gallus 57540 R-GGA-77312 https://reactome.org/PathwayBrowser/#/R-GGA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Gallus gallus 57540 R-GGA-77323 https://reactome.org/PathwayBrowser/#/R-GGA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Gallus gallus 57540 R-GGA-77331 https://reactome.org/PathwayBrowser/#/R-GGA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Gallus gallus 57540 R-GGA-77342 https://reactome.org/PathwayBrowser/#/R-GGA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Gallus gallus 57540 R-GGA-8870346 https://reactome.org/PathwayBrowser/#/R-GGA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Gallus gallus 57540 R-GGA-888548 https://reactome.org/PathwayBrowser/#/R-GGA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Gallus gallus 57540 R-GGA-8936442 https://reactome.org/PathwayBrowser/#/R-GGA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Gallus gallus 57540 R-GGA-8938073 https://reactome.org/PathwayBrowser/#/R-GGA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Gallus gallus 57540 R-GGA-8938076 https://reactome.org/PathwayBrowser/#/R-GGA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Gallus gallus 57540 R-GGA-8939959 https://reactome.org/PathwayBrowser/#/R-GGA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Gallus gallus 57540 R-GGA-8940070 https://reactome.org/PathwayBrowser/#/R-GGA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Gallus gallus 57540 R-GGA-8948800 https://reactome.org/PathwayBrowser/#/R-GGA-8948800 TNKS and TNKS2 PARylate PTEN IEA Gallus gallus 57540 R-GGA-8955030 https://reactome.org/PathwayBrowser/#/R-GGA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Gallus gallus 57540 R-GGA-8956458 https://reactome.org/PathwayBrowser/#/R-GGA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Gallus gallus 57540 R-GGA-9023968 https://reactome.org/PathwayBrowser/#/R-GGA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Gallus gallus 57540 R-GGA-9024766 https://reactome.org/PathwayBrowser/#/R-GGA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Gallus gallus 57540 R-GGA-9620532 https://reactome.org/PathwayBrowser/#/R-GGA-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Gallus gallus 57540 R-GGA-9667952 https://reactome.org/PathwayBrowser/#/R-GGA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Gallus gallus 57540 R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 57540 R-GGA-9727349 https://reactome.org/PathwayBrowser/#/R-GGA-9727349 XDH dehydrogenates xanthine to form urate IEA Gallus gallus 57540 R-GGA-9748945 https://reactome.org/PathwayBrowser/#/R-GGA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Gallus gallus 57540 R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 57540 R-GGA-9759549 https://reactome.org/PathwayBrowser/#/R-GGA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Gallus gallus 57540 R-GGA-9853499 https://reactome.org/PathwayBrowser/#/R-GGA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 57540 R-GGA-9854463 https://reactome.org/PathwayBrowser/#/R-GGA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Gallus gallus 57540 R-GGA-9856871 https://reactome.org/PathwayBrowser/#/R-GGA-9856871 MDH1 reduces OA IEA Gallus gallus 57540 R-GGA-9861616 https://reactome.org/PathwayBrowser/#/R-GGA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 57540 R-GGA-9861626 https://reactome.org/PathwayBrowser/#/R-GGA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Gallus gallus 57540 R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 57540 R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 57540 R-HSA-109343 https://reactome.org/PathwayBrowser/#/R-HSA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA TAS Homo sapiens 57540 R-HSA-1222412 https://reactome.org/PathwayBrowser/#/R-HSA-1222412 lpdC dimer reactivates dlaT TAS Homo sapiens 57540 R-HSA-1222583 https://reactome.org/PathwayBrowser/#/R-HSA-1222583 MscR reduces nitrosomycothiol to ammonia TAS Homo sapiens 57540 R-HSA-1614362 https://reactome.org/PathwayBrowser/#/R-HSA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases TAS Homo sapiens 57540 R-HSA-163217 https://reactome.org/PathwayBrowser/#/R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 TAS Homo sapiens 57540 R-HSA-169683 https://reactome.org/PathwayBrowser/#/R-HSA-169683 IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol IEA Homo sapiens 57540 R-HSA-173597 https://reactome.org/PathwayBrowser/#/R-HSA-173597 UDP-glucose is oxidised to UDP-glucuronate TAS Homo sapiens 57540 R-HSA-174401 https://reactome.org/PathwayBrowser/#/R-HSA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy TAS Homo sapiens 57540 R-HSA-1855178 https://reactome.org/PathwayBrowser/#/R-HSA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol TAS Homo sapiens 57540 R-HSA-192097 https://reactome.org/PathwayBrowser/#/R-HSA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one TAS Homo sapiens 57540 R-HSA-193073 https://reactome.org/PathwayBrowser/#/R-HSA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST TAS Homo sapiens 57540 R-HSA-193455 https://reactome.org/PathwayBrowser/#/R-HSA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 57540 R-HSA-193508 https://reactome.org/PathwayBrowser/#/R-HSA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 57540 R-HSA-193789 https://reactome.org/PathwayBrowser/#/R-HSA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one TAS Homo sapiens 57540 R-HSA-193816 https://reactome.org/PathwayBrowser/#/R-HSA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one TAS Homo sapiens 57540 R-HSA-194642 https://reactome.org/PathwayBrowser/#/R-HSA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one TAS Homo sapiens 57540 R-HSA-194718 https://reactome.org/PathwayBrowser/#/R-HSA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) TAS Homo sapiens 57540 R-HSA-196350 https://reactome.org/PathwayBrowser/#/R-HSA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione TAS Homo sapiens 57540 R-HSA-196372 https://reactome.org/PathwayBrowser/#/R-HSA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol TAS Homo sapiens 57540 R-HSA-197198 https://reactome.org/PathwayBrowser/#/R-HSA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ TAS Homo sapiens 57540 R-HSA-197271 https://reactome.org/PathwayBrowser/#/R-HSA-197271 NADSYN1 hexamer amidates NAAD to NAD+ TAS Homo sapiens 57540 R-HSA-198824 https://reactome.org/PathwayBrowser/#/R-HSA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme TAS Homo sapiens 57540 R-HSA-2046084 https://reactome.org/PathwayBrowser/#/R-HSA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA TAS Homo sapiens 57540 R-HSA-2046089 https://reactome.org/PathwayBrowser/#/R-HSA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA TAS Homo sapiens 57540 R-HSA-2046092 https://reactome.org/PathwayBrowser/#/R-HSA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA TAS Homo sapiens 57540 R-HSA-2046096 https://reactome.org/PathwayBrowser/#/R-HSA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA TAS Homo sapiens 57540 R-HSA-2046097 https://reactome.org/PathwayBrowser/#/R-HSA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 57540 R-HSA-2046099 https://reactome.org/PathwayBrowser/#/R-HSA-2046099 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA IEA Homo sapiens 57540 R-HSA-204617 https://reactome.org/PathwayBrowser/#/R-HSA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A TAS Homo sapiens 57540 R-HSA-204647 https://reactome.org/PathwayBrowser/#/R-HSA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine TAS Homo sapiens 57540 R-HSA-204662 https://reactome.org/PathwayBrowser/#/R-HSA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A TAS Homo sapiens 57540 R-HSA-2161662 https://reactome.org/PathwayBrowser/#/R-HSA-2161662 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD IEA Homo sapiens 57540 R-HSA-2161732 https://reactome.org/PathwayBrowser/#/R-HSA-2161732 TXB2 is converted to 11dh-TXB2 by TXDH TAS Homo sapiens 57540 R-HSA-2161779 https://reactome.org/PathwayBrowser/#/R-HSA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD TAS Homo sapiens 57540 R-HSA-2161789 https://reactome.org/PathwayBrowser/#/R-HSA-2161789 15S-HETE is oxidised to 15-oxoETE by 15-HEDH TAS Homo sapiens 57540 R-HSA-2162078 https://reactome.org/PathwayBrowser/#/R-HSA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ TAS Homo sapiens 57540 R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 57540 R-HSA-2187325 https://reactome.org/PathwayBrowser/#/R-HSA-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 TAS Homo sapiens 57540 R-HSA-2454081 https://reactome.org/PathwayBrowser/#/R-HSA-2454081 RDH5 oxidises 11cROL to 11cRAL TAS Homo sapiens 57540 R-HSA-2466832 https://reactome.org/PathwayBrowser/#/R-HSA-2466832 Defective RDH5 does not oxidise 11cROL to 11cRAL and causes RPA TAS Homo sapiens 57540 R-HSA-3371467 https://reactome.org/PathwayBrowser/#/R-HSA-3371467 SIRT1 deacetylates HSF1 TAS Homo sapiens 57540 R-HSA-3640858 https://reactome.org/PathwayBrowser/#/R-HSA-3640858 Tankyrase ADP-ribosylates AXIN TAS Homo sapiens 57540 R-HSA-380608 https://reactome.org/PathwayBrowser/#/R-HSA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid TAS Homo sapiens 57540 R-HSA-389609 https://reactome.org/PathwayBrowser/#/R-HSA-389609 ALDH3A2-2 oxidizes pristanal to pristanate TAS Homo sapiens 57540 R-HSA-389995 https://reactome.org/PathwayBrowser/#/R-HSA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ TAS Homo sapiens 57540 R-HSA-390251 https://reactome.org/PathwayBrowser/#/R-HSA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 57540 R-HSA-390276 https://reactome.org/PathwayBrowser/#/R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA TAS Homo sapiens 57540 R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA TAS Homo sapiens 57540 R-HSA-427514 https://reactome.org/PathwayBrowser/#/R-HSA-427514 eNoSC deacetylates histone H3 TAS Homo sapiens 57540 R-HSA-450971 https://reactome.org/PathwayBrowser/#/R-HSA-450971 NNT dimer transfers proton from NADPH to NAD+ TAS Homo sapiens 57540 R-HSA-508369 https://reactome.org/PathwayBrowser/#/R-HSA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ TAS Homo sapiens 57540 R-HSA-508473 https://reactome.org/PathwayBrowser/#/R-HSA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ TAS Homo sapiens 57540 R-HSA-5211239 https://reactome.org/PathwayBrowser/#/R-HSA-5211239 SIRT1 deacetylates TAF1B in SL1 complex IEA Homo sapiens 57540 R-HSA-5226904 https://reactome.org/PathwayBrowser/#/R-HSA-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it TAS Homo sapiens 57540 R-HSA-5336421 https://reactome.org/PathwayBrowser/#/R-HSA-5336421 DT fragment A ADP-ribosylates target cell EEF TAS Homo sapiens 57540 R-HSA-5362518 https://reactome.org/PathwayBrowser/#/R-HSA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL TAS Homo sapiens 57540 R-HSA-5362522 https://reactome.org/PathwayBrowser/#/R-HSA-5362522 ALDHs oxidise atRAL to atRA TAS Homo sapiens 57540 R-HSA-5362564 https://reactome.org/PathwayBrowser/#/R-HSA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro TAS Homo sapiens 57540 R-HSA-5362721 https://reactome.org/PathwayBrowser/#/R-HSA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL TAS Homo sapiens 57540 R-HSA-5579084 https://reactome.org/PathwayBrowser/#/R-HSA-5579084 Defective AHCY does not hydrolyse AdoHcy TAS Homo sapiens 57540 R-HSA-5610036 https://reactome.org/PathwayBrowser/#/R-HSA-5610036 Defective GALE does not epimerise UDP-Gal to UDP-Glc TAS Homo sapiens 57540 R-HSA-5651723 https://reactome.org/PathwayBrowser/#/R-HSA-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate TAS Homo sapiens 57540 R-HSA-5652195 https://reactome.org/PathwayBrowser/#/R-HSA-5652195 SORD oxidizes D-sorbitol to Fru TAS Homo sapiens 57540 R-HSA-5661290 https://reactome.org/PathwayBrowser/#/R-HSA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate TAS Homo sapiens 57540 R-HSA-5662471 https://reactome.org/PathwayBrowser/#/R-HSA-5662471 SORD tetramer oxidizes xylitol to D-xylulose TAS Homo sapiens 57540 R-HSA-5685953 https://reactome.org/PathwayBrowser/#/R-HSA-5685953 SIRT6 deacetylates RBBP8 TAS Homo sapiens 57540 R-HSA-5687653 https://reactome.org/PathwayBrowser/#/R-HSA-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate TAS Homo sapiens 57540 R-HSA-5688276 https://reactome.org/PathwayBrowser/#/R-HSA-5688276 SIRT4 transfers ADPRib to GLUD TAS Homo sapiens 57540 R-HSA-5688289 https://reactome.org/PathwayBrowser/#/R-HSA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 TAS Homo sapiens 57540 R-HSA-5688294 https://reactome.org/PathwayBrowser/#/R-HSA-5688294 SIRT5 deacetylates Cytochrome C TAS Homo sapiens 57540 R-HSA-5692237 https://reactome.org/PathwayBrowser/#/R-HSA-5692237 ADH5 oxidises S-HMGSH to S-FGSH TAS Homo sapiens 57540 R-HSA-5692261 https://reactome.org/PathwayBrowser/#/R-HSA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM TAS Homo sapiens 57540 R-HSA-5694018 https://reactome.org/PathwayBrowser/#/R-HSA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate TAS Homo sapiens 57540 R-HSA-5696080 https://reactome.org/PathwayBrowser/#/R-HSA-5696080 ALDH3B1 oxidises HXAL to PALM TAS Homo sapiens 57540 R-HSA-5696091 https://reactome.org/PathwayBrowser/#/R-HSA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH TAS Homo sapiens 57540 R-HSA-5696101 https://reactome.org/PathwayBrowser/#/R-HSA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA TAS Homo sapiens 57540 R-HSA-5696457 https://reactome.org/PathwayBrowser/#/R-HSA-5696457 BDH2 dehydrogenates 3HBA TAS Homo sapiens 57540 R-HSA-5696655 https://reactome.org/PathwayBrowser/#/R-HSA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates TAS Homo sapiens 57540 R-HSA-6782296 https://reactome.org/PathwayBrowser/#/R-HSA-6782296 DUS2:EPRS reduces uridine to dihydrouridine in tRNAs IEA Homo sapiens 57540 R-HSA-6783939 https://reactome.org/PathwayBrowser/#/R-HSA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 57540 R-HSA-6784399 https://reactome.org/PathwayBrowser/#/R-HSA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate TAS Homo sapiens 57540 R-HSA-6797955 https://reactome.org/PathwayBrowser/#/R-HSA-6797955 ALDH7A1 oxidises BETALD to BET TAS Homo sapiens 57540 R-HSA-6798667 https://reactome.org/PathwayBrowser/#/R-HSA-6798667 TDH tetramer oxidises L-Thr to 2A-3OB TAS Homo sapiens 57540 R-HSA-6801328 https://reactome.org/PathwayBrowser/#/R-HSA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF TAS Homo sapiens 57540 R-HSA-6806831 https://reactome.org/PathwayBrowser/#/R-HSA-6806831 CYB5Rs reduce MetHb to HbA TAS Homo sapiens 57540 R-HSA-6807826 https://reactome.org/PathwayBrowser/#/R-HSA-6807826 LDHAL6B reduces PYR to LACT TAS Homo sapiens 57540 R-HSA-6808464 https://reactome.org/PathwayBrowser/#/R-HSA-6808464 ALDH3B2 oxidises HXAL to PALM TAS Homo sapiens 57540 R-HSA-6809264 https://reactome.org/PathwayBrowser/#/R-HSA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 57540 R-HSA-6813749 https://reactome.org/PathwayBrowser/#/R-HSA-6813749 ALDH1A1 oxidises GA to DGA TAS Homo sapiens 57540 R-HSA-70369 https://reactome.org/PathwayBrowser/#/R-HSA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc TAS Homo sapiens 57540 R-HSA-70449 https://reactome.org/PathwayBrowser/#/R-HSA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ TAS Homo sapiens 57540 R-HSA-70482 https://reactome.org/PathwayBrowser/#/R-HSA-70482 GAPDH tetramers reduce 1,3BPG to GA3P TAS Homo sapiens 57540 R-HSA-70510 https://reactome.org/PathwayBrowser/#/R-HSA-70510 LDH tetramer oxidises LACT to PYR TAS Homo sapiens 57540 R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] TAS Homo sapiens 57540 R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] TAS Homo sapiens 57540 R-HSA-70664 https://reactome.org/PathwayBrowser/#/R-HSA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 57540 R-HSA-70679 https://reactome.org/PathwayBrowser/#/R-HSA-70679 ALDH4A1 oxidises L-GluSS to Glu TAS Homo sapiens 57540 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 57540 R-HSA-70837 https://reactome.org/PathwayBrowser/#/R-HSA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ TAS Homo sapiens 57540 R-HSA-70885 https://reactome.org/PathwayBrowser/#/R-HSA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ TAS Homo sapiens 57540 R-HSA-70893 https://reactome.org/PathwayBrowser/#/R-HSA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ TAS Homo sapiens 57540 R-HSA-70903 https://reactome.org/PathwayBrowser/#/R-HSA-70903 urocanate + H2O => 4-imidazolone-5-propionate TAS Homo sapiens 57540 R-HSA-70940 https://reactome.org/PathwayBrowser/#/R-HSA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ TAS Homo sapiens 57540 R-HSA-70941 https://reactome.org/PathwayBrowser/#/R-HSA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ TAS Homo sapiens 57540 R-HSA-70967 https://reactome.org/PathwayBrowser/#/R-HSA-70967 IDH3 complex decarboxylates isocitrate TAS Homo sapiens 57540 R-HSA-70979 https://reactome.org/PathwayBrowser/#/R-HSA-70979 MDH2 dimer dehydrogenates MAL TAS Homo sapiens 57540 R-HSA-71037 https://reactome.org/PathwayBrowser/#/R-HSA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ TAS Homo sapiens 57540 R-HSA-71130 https://reactome.org/PathwayBrowser/#/R-HSA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ TAS Homo sapiens 57540 R-HSA-71239 https://reactome.org/PathwayBrowser/#/R-HSA-71239 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ IEA Homo sapiens 57540 R-HSA-71260 https://reactome.org/PathwayBrowser/#/R-HSA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT TAS Homo sapiens 57540 R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 57540 R-HSA-71707 https://reactome.org/PathwayBrowser/#/R-HSA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ TAS Homo sapiens 57540 R-HSA-71723 https://reactome.org/PathwayBrowser/#/R-HSA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] TAS Homo sapiens 57540 R-HSA-71849 https://reactome.org/PathwayBrowser/#/R-HSA-71849 LDH tetramer reduces PYR to LACT TAS Homo sapiens 57540 R-HSA-73794 https://reactome.org/PathwayBrowser/#/R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] TAS Homo sapiens 57540 R-HSA-73912 https://reactome.org/PathwayBrowser/#/R-HSA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ TAS Homo sapiens 57540 R-HSA-73920 https://reactome.org/PathwayBrowser/#/R-HSA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ TAS Homo sapiens 57540 R-HSA-75889 https://reactome.org/PathwayBrowser/#/R-HSA-75889 DHAP is converted to G3P by GPD1/GPD1L TAS Homo sapiens 57540 R-HSA-77254 https://reactome.org/PathwayBrowser/#/R-HSA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H TAS Homo sapiens 57540 R-HSA-77283 https://reactome.org/PathwayBrowser/#/R-HSA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H TAS Homo sapiens 57540 R-HSA-77303 https://reactome.org/PathwayBrowser/#/R-HSA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H TAS Homo sapiens 57540 R-HSA-77312 https://reactome.org/PathwayBrowser/#/R-HSA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H TAS Homo sapiens 57540 R-HSA-77323 https://reactome.org/PathwayBrowser/#/R-HSA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H TAS Homo sapiens 57540 R-HSA-77331 https://reactome.org/PathwayBrowser/#/R-HSA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H TAS Homo sapiens 57540 R-HSA-77342 https://reactome.org/PathwayBrowser/#/R-HSA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H TAS Homo sapiens 57540 R-HSA-8870346 https://reactome.org/PathwayBrowser/#/R-HSA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose TAS Homo sapiens 57540 R-HSA-888548 https://reactome.org/PathwayBrowser/#/R-HSA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA TAS Homo sapiens 57540 R-HSA-8936442 https://reactome.org/PathwayBrowser/#/R-HSA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds TAS Homo sapiens 57540 R-HSA-8938073 https://reactome.org/PathwayBrowser/#/R-HSA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) TAS Homo sapiens 57540 R-HSA-8938076 https://reactome.org/PathwayBrowser/#/R-HSA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose TAS Homo sapiens 57540 R-HSA-8939959 https://reactome.org/PathwayBrowser/#/R-HSA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ TAS Homo sapiens 57540 R-HSA-8940070 https://reactome.org/PathwayBrowser/#/R-HSA-8940070 NT5E:Zn2+ hydrolyses NAD+ TAS Homo sapiens 57540 R-HSA-8948800 https://reactome.org/PathwayBrowser/#/R-HSA-8948800 TNKS and TNKS2 PARylate PTEN TAS Homo sapiens 57540 R-HSA-8955030 https://reactome.org/PathwayBrowser/#/R-HSA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ TAS Homo sapiens 57540 R-HSA-8956427 https://reactome.org/PathwayBrowser/#/R-HSA-8956427 RETSAT reduces atROL to at-13,14-dhROL IEA Homo sapiens 57540 R-HSA-8956458 https://reactome.org/PathwayBrowser/#/R-HSA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ TAS Homo sapiens 57540 R-HSA-9012268 https://reactome.org/PathwayBrowser/#/R-HSA-9012268 ME2 tetramer decarboxylates MAL to PYR TAS Homo sapiens 57540 R-HSA-9023968 https://reactome.org/PathwayBrowser/#/R-HSA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 TAS Homo sapiens 57540 R-HSA-9024766 https://reactome.org/PathwayBrowser/#/R-HSA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 TAS Homo sapiens 57540 R-HSA-9604829 https://reactome.org/PathwayBrowser/#/R-HSA-9604829 SIRT6 deacetylates histones at NOTCH1 and NOTCH4 gene promoters IEA Homo sapiens 57540 R-HSA-9620532 https://reactome.org/PathwayBrowser/#/R-HSA-9620532 SIRT1,SIRT3 deacetylate FOXO3 TAS Homo sapiens 57540 R-HSA-9626962 https://reactome.org/PathwayBrowser/#/R-HSA-9626962 SIRT1 deacetylates FOXO1 IEA Homo sapiens 57540 R-HSA-9637699 https://reactome.org/PathwayBrowser/#/R-HSA-9637699 CpnT hydrolyses NAD+ TAS Homo sapiens 57540 R-HSA-9667952 https://reactome.org/PathwayBrowser/#/R-HSA-9667952 ANKLE2 is deacetylated by SIRT2 TAS Homo sapiens 57540 R-HSA-9686061 https://reactome.org/PathwayBrowser/#/R-HSA-9686061 Nucleoprotein is ADP-ribosylated TAS Homo sapiens 57540 R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 57540 R-HSA-9727349 https://reactome.org/PathwayBrowser/#/R-HSA-9727349 XDH dehydrogenates xanthine to form urate TAS Homo sapiens 57540 R-HSA-9729279 https://reactome.org/PathwayBrowser/#/R-HSA-9729279 Nucleoprotein is ADP-ribosylated IEA Homo sapiens 57540 R-HSA-9748945 https://reactome.org/PathwayBrowser/#/R-HSA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP TAS Homo sapiens 57540 R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 57540 R-HSA-9759549 https://reactome.org/PathwayBrowser/#/R-HSA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin TAS Homo sapiens 57540 R-HSA-977348 https://reactome.org/PathwayBrowser/#/R-HSA-977348 PHGDH tetramer dehydrogenates 3PG TAS Homo sapiens 57540 R-HSA-9853499 https://reactome.org/PathwayBrowser/#/R-HSA-9853499 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 57540 R-HSA-9854463 https://reactome.org/PathwayBrowser/#/R-HSA-9854463 SIRT3 deacetylates AcK-IDH2 dimer TAS Homo sapiens 57540 R-HSA-9856871 https://reactome.org/PathwayBrowser/#/R-HSA-9856871 MDH1 reduces OA TAS Homo sapiens 57540 R-HSA-9861616 https://reactome.org/PathwayBrowser/#/R-HSA-9861616 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 57540 R-HSA-9861626 https://reactome.org/PathwayBrowser/#/R-HSA-9861626 SIRT4 cleaves lipoyl from DLAT TAS Homo sapiens 57540 R-MMU-109343 https://reactome.org/PathwayBrowser/#/R-MMU-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Mus musculus 57540 R-MMU-1614362 https://reactome.org/PathwayBrowser/#/R-MMU-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Mus musculus 57540 R-MMU-163217 https://reactome.org/PathwayBrowser/#/R-MMU-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Mus musculus 57540 R-MMU-173597 https://reactome.org/PathwayBrowser/#/R-MMU-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Mus musculus 57540 R-MMU-174401 https://reactome.org/PathwayBrowser/#/R-MMU-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Mus musculus 57540 R-MMU-1855178 https://reactome.org/PathwayBrowser/#/R-MMU-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Mus musculus 57540 R-MMU-192097 https://reactome.org/PathwayBrowser/#/R-MMU-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Mus musculus 57540 R-MMU-193073 https://reactome.org/PathwayBrowser/#/R-MMU-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Mus musculus 57540 R-MMU-193455 https://reactome.org/PathwayBrowser/#/R-MMU-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 57540 R-MMU-193508 https://reactome.org/PathwayBrowser/#/R-MMU-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 57540 R-MMU-193789 https://reactome.org/PathwayBrowser/#/R-MMU-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Mus musculus 57540 R-MMU-193816 https://reactome.org/PathwayBrowser/#/R-MMU-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Mus musculus 57540 R-MMU-194642 https://reactome.org/PathwayBrowser/#/R-MMU-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Mus musculus 57540 R-MMU-194718 https://reactome.org/PathwayBrowser/#/R-MMU-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Mus musculus 57540 R-MMU-196350 https://reactome.org/PathwayBrowser/#/R-MMU-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Mus musculus 57540 R-MMU-196372 https://reactome.org/PathwayBrowser/#/R-MMU-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Mus musculus 57540 R-MMU-197198 https://reactome.org/PathwayBrowser/#/R-MMU-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Mus musculus 57540 R-MMU-197271 https://reactome.org/PathwayBrowser/#/R-MMU-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Mus musculus 57540 R-MMU-198824 https://reactome.org/PathwayBrowser/#/R-MMU-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Mus musculus 57540 R-MMU-2046084 https://reactome.org/PathwayBrowser/#/R-MMU-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Mus musculus 57540 R-MMU-2046089 https://reactome.org/PathwayBrowser/#/R-MMU-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Mus musculus 57540 R-MMU-2046092 https://reactome.org/PathwayBrowser/#/R-MMU-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Mus musculus 57540 R-MMU-2046096 https://reactome.org/PathwayBrowser/#/R-MMU-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Mus musculus 57540 R-MMU-2046097 https://reactome.org/PathwayBrowser/#/R-MMU-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 57540 R-MMU-204617 https://reactome.org/PathwayBrowser/#/R-MMU-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Mus musculus 57540 R-MMU-204647 https://reactome.org/PathwayBrowser/#/R-MMU-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Mus musculus 57540 R-MMU-204662 https://reactome.org/PathwayBrowser/#/R-MMU-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Mus musculus 57540 R-MMU-2161779 https://reactome.org/PathwayBrowser/#/R-MMU-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Mus musculus 57540 R-MMU-2162078 https://reactome.org/PathwayBrowser/#/R-MMU-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Mus musculus 57540 R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 57540 R-MMU-2187325 https://reactome.org/PathwayBrowser/#/R-MMU-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Mus musculus 57540 R-MMU-2454081 https://reactome.org/PathwayBrowser/#/R-MMU-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Mus musculus 57540 R-MMU-3371467 https://reactome.org/PathwayBrowser/#/R-MMU-3371467 SIRT1 deacetylates HSF1 IEA Mus musculus 57540 R-MMU-3640858 https://reactome.org/PathwayBrowser/#/R-MMU-3640858 Tankyrase ADP-ribosylates AXIN IEA Mus musculus 57540 R-MMU-380608 https://reactome.org/PathwayBrowser/#/R-MMU-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Mus musculus 57540 R-MMU-389609 https://reactome.org/PathwayBrowser/#/R-MMU-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Mus musculus 57540 R-MMU-389995 https://reactome.org/PathwayBrowser/#/R-MMU-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Mus musculus 57540 R-MMU-390251 https://reactome.org/PathwayBrowser/#/R-MMU-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 57540 R-MMU-450971 https://reactome.org/PathwayBrowser/#/R-MMU-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Mus musculus 57540 R-MMU-508369 https://reactome.org/PathwayBrowser/#/R-MMU-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Mus musculus 57540 R-MMU-508473 https://reactome.org/PathwayBrowser/#/R-MMU-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Mus musculus 57540 R-MMU-5211233 https://reactome.org/PathwayBrowser/#/R-MMU-5211233 Sirt1 deacetylates Taf1b in SL1 complex TAS Mus musculus 57540 R-MMU-5226904 https://reactome.org/PathwayBrowser/#/R-MMU-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Mus musculus 57540 R-MMU-5362518 https://reactome.org/PathwayBrowser/#/R-MMU-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Mus musculus 57540 R-MMU-5362522 https://reactome.org/PathwayBrowser/#/R-MMU-5362522 ALDHs oxidise atRAL to atRA IEA Mus musculus 57540 R-MMU-5362564 https://reactome.org/PathwayBrowser/#/R-MMU-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Mus musculus 57540 R-MMU-5362721 https://reactome.org/PathwayBrowser/#/R-MMU-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Mus musculus 57540 R-MMU-5651723 https://reactome.org/PathwayBrowser/#/R-MMU-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Mus musculus 57540 R-MMU-5652195 https://reactome.org/PathwayBrowser/#/R-MMU-5652195 SORD oxidizes D-sorbitol to Fru IEA Mus musculus 57540 R-MMU-5661290 https://reactome.org/PathwayBrowser/#/R-MMU-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Mus musculus 57540 R-MMU-5662471 https://reactome.org/PathwayBrowser/#/R-MMU-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Mus musculus 57540 R-MMU-5685953 https://reactome.org/PathwayBrowser/#/R-MMU-5685953 SIRT6 deacetylates RBBP8 IEA Mus musculus 57540 R-MMU-5687653 https://reactome.org/PathwayBrowser/#/R-MMU-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Mus musculus 57540 R-MMU-5688276 https://reactome.org/PathwayBrowser/#/R-MMU-5688276 SIRT4 transfers ADPRib to GLUD IEA Mus musculus 57540 R-MMU-5688289 https://reactome.org/PathwayBrowser/#/R-MMU-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Mus musculus 57540 R-MMU-5688294 https://reactome.org/PathwayBrowser/#/R-MMU-5688294 SIRT5 deacetylates Cytochrome C IEA Mus musculus 57540 R-MMU-5692237 https://reactome.org/PathwayBrowser/#/R-MMU-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Mus musculus 57540 R-MMU-5692261 https://reactome.org/PathwayBrowser/#/R-MMU-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Mus musculus 57540 R-MMU-5694018 https://reactome.org/PathwayBrowser/#/R-MMU-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Mus musculus 57540 R-MMU-5696080 https://reactome.org/PathwayBrowser/#/R-MMU-5696080 ALDH3B1 oxidises HXAL to PALM IEA Mus musculus 57540 R-MMU-5696091 https://reactome.org/PathwayBrowser/#/R-MMU-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Mus musculus 57540 R-MMU-5696101 https://reactome.org/PathwayBrowser/#/R-MMU-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Mus musculus 57540 R-MMU-5696457 https://reactome.org/PathwayBrowser/#/R-MMU-5696457 BDH2 dehydrogenates 3HBA IEA Mus musculus 57540 R-MMU-5696655 https://reactome.org/PathwayBrowser/#/R-MMU-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Mus musculus 57540 R-MMU-6783939 https://reactome.org/PathwayBrowser/#/R-MMU-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 57540 R-MMU-6784399 https://reactome.org/PathwayBrowser/#/R-MMU-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Mus musculus 57540 R-MMU-6797955 https://reactome.org/PathwayBrowser/#/R-MMU-6797955 ALDH7A1 oxidises BETALD to BET IEA Mus musculus 57540 R-MMU-6801328 https://reactome.org/PathwayBrowser/#/R-MMU-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Mus musculus 57540 R-MMU-6806831 https://reactome.org/PathwayBrowser/#/R-MMU-6806831 CYB5Rs reduce MetHb to HbA IEA Mus musculus 57540 R-MMU-6807826 https://reactome.org/PathwayBrowser/#/R-MMU-6807826 LDHAL6B reduces PYR to LACT IEA Mus musculus 57540 R-MMU-6808464 https://reactome.org/PathwayBrowser/#/R-MMU-6808464 ALDH3B2 oxidises HXAL to PALM IEA Mus musculus 57540 R-MMU-6809264 https://reactome.org/PathwayBrowser/#/R-MMU-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 57540 R-MMU-6813749 https://reactome.org/PathwayBrowser/#/R-MMU-6813749 ALDH1A1 oxidises GA to DGA IEA Mus musculus 57540 R-MMU-70369 https://reactome.org/PathwayBrowser/#/R-MMU-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Mus musculus 57540 R-MMU-70449 https://reactome.org/PathwayBrowser/#/R-MMU-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Mus musculus 57540 R-MMU-70482 https://reactome.org/PathwayBrowser/#/R-MMU-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Mus musculus 57540 R-MMU-70510 https://reactome.org/PathwayBrowser/#/R-MMU-70510 LDH tetramer oxidises LACT to PYR IEA Mus musculus 57540 R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Mus musculus 57540 R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Mus musculus 57540 R-MMU-70664 https://reactome.org/PathwayBrowser/#/R-MMU-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 57540 R-MMU-70679 https://reactome.org/PathwayBrowser/#/R-MMU-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Mus musculus 57540 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 57540 R-MMU-70837 https://reactome.org/PathwayBrowser/#/R-MMU-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Mus musculus 57540 R-MMU-70885 https://reactome.org/PathwayBrowser/#/R-MMU-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Mus musculus 57540 R-MMU-70893 https://reactome.org/PathwayBrowser/#/R-MMU-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Mus musculus 57540 R-MMU-70903 https://reactome.org/PathwayBrowser/#/R-MMU-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Mus musculus 57540 R-MMU-70940 https://reactome.org/PathwayBrowser/#/R-MMU-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Mus musculus 57540 R-MMU-70941 https://reactome.org/PathwayBrowser/#/R-MMU-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Mus musculus 57540 R-MMU-70967 https://reactome.org/PathwayBrowser/#/R-MMU-70967 IDH3 complex decarboxylates isocitrate IEA Mus musculus 57540 R-MMU-70979 https://reactome.org/PathwayBrowser/#/R-MMU-70979 MDH2 dimer dehydrogenates MAL IEA Mus musculus 57540 R-MMU-71037 https://reactome.org/PathwayBrowser/#/R-MMU-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Mus musculus 57540 R-MMU-71130 https://reactome.org/PathwayBrowser/#/R-MMU-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Mus musculus 57540 R-MMU-71260 https://reactome.org/PathwayBrowser/#/R-MMU-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Mus musculus 57540 R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 57540 R-MMU-71707 https://reactome.org/PathwayBrowser/#/R-MMU-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Mus musculus 57540 R-MMU-71723 https://reactome.org/PathwayBrowser/#/R-MMU-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Mus musculus 57540 R-MMU-71849 https://reactome.org/PathwayBrowser/#/R-MMU-71849 LDH tetramer reduces PYR to LACT IEA Mus musculus 57540 R-MMU-73794 https://reactome.org/PathwayBrowser/#/R-MMU-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Mus musculus 57540 R-MMU-73912 https://reactome.org/PathwayBrowser/#/R-MMU-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Mus musculus 57540 R-MMU-73920 https://reactome.org/PathwayBrowser/#/R-MMU-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Mus musculus 57540 R-MMU-75889 https://reactome.org/PathwayBrowser/#/R-MMU-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Mus musculus 57540 R-MMU-77254 https://reactome.org/PathwayBrowser/#/R-MMU-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Mus musculus 57540 R-MMU-77283 https://reactome.org/PathwayBrowser/#/R-MMU-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Mus musculus 57540 R-MMU-77303 https://reactome.org/PathwayBrowser/#/R-MMU-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Mus musculus 57540 R-MMU-77312 https://reactome.org/PathwayBrowser/#/R-MMU-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Mus musculus 57540 R-MMU-77323 https://reactome.org/PathwayBrowser/#/R-MMU-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Mus musculus 57540 R-MMU-77331 https://reactome.org/PathwayBrowser/#/R-MMU-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Mus musculus 57540 R-MMU-77342 https://reactome.org/PathwayBrowser/#/R-MMU-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Mus musculus 57540 R-MMU-8870346 https://reactome.org/PathwayBrowser/#/R-MMU-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Mus musculus 57540 R-MMU-888548 https://reactome.org/PathwayBrowser/#/R-MMU-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Mus musculus 57540 R-MMU-8936442 https://reactome.org/PathwayBrowser/#/R-MMU-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Mus musculus 57540 R-MMU-8938073 https://reactome.org/PathwayBrowser/#/R-MMU-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Mus musculus 57540 R-MMU-8938076 https://reactome.org/PathwayBrowser/#/R-MMU-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Mus musculus 57540 R-MMU-8939959 https://reactome.org/PathwayBrowser/#/R-MMU-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Mus musculus 57540 R-MMU-8940070 https://reactome.org/PathwayBrowser/#/R-MMU-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Mus musculus 57540 R-MMU-8948800 https://reactome.org/PathwayBrowser/#/R-MMU-8948800 TNKS and TNKS2 PARylate PTEN IEA Mus musculus 57540 R-MMU-8955030 https://reactome.org/PathwayBrowser/#/R-MMU-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Mus musculus 57540 R-MMU-8956439 https://reactome.org/PathwayBrowser/#/R-MMU-8956439 Retsat reduces atROL to at-13,14-dhROL TAS Mus musculus 57540 R-MMU-8956458 https://reactome.org/PathwayBrowser/#/R-MMU-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Mus musculus 57540 R-MMU-9012268 https://reactome.org/PathwayBrowser/#/R-MMU-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Mus musculus 57540 R-MMU-9023968 https://reactome.org/PathwayBrowser/#/R-MMU-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Mus musculus 57540 R-MMU-9024766 https://reactome.org/PathwayBrowser/#/R-MMU-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Mus musculus 57540 R-MMU-9604841 https://reactome.org/PathwayBrowser/#/R-MMU-9604841 Sirt6 deacetylates histones at Notch1 and Notch4 gene promoters TAS Mus musculus 57540 R-MMU-9620532 https://reactome.org/PathwayBrowser/#/R-MMU-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Mus musculus 57540 R-MMU-9626966 https://reactome.org/PathwayBrowser/#/R-MMU-9626966 Sirt1 deacetylates Foxo1 TAS Mus musculus 57540 R-MMU-9667952 https://reactome.org/PathwayBrowser/#/R-MMU-9667952 ANKLE2 is deacetylated by SIRT2 IEA Mus musculus 57540 R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 57540 R-MMU-9727349 https://reactome.org/PathwayBrowser/#/R-MMU-9727349 XDH dehydrogenates xanthine to form urate IEA Mus musculus 57540 R-MMU-9748945 https://reactome.org/PathwayBrowser/#/R-MMU-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Mus musculus 57540 R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 57540 R-MMU-9759549 https://reactome.org/PathwayBrowser/#/R-MMU-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Mus musculus 57540 R-MMU-977348 https://reactome.org/PathwayBrowser/#/R-MMU-977348 PHGDH tetramer dehydrogenates 3PG IEA Mus musculus 57540 R-MMU-9853499 https://reactome.org/PathwayBrowser/#/R-MMU-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 57540 R-MMU-9854463 https://reactome.org/PathwayBrowser/#/R-MMU-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Mus musculus 57540 R-MMU-9856871 https://reactome.org/PathwayBrowser/#/R-MMU-9856871 MDH1 reduces OA IEA Mus musculus 57540 R-MMU-9861616 https://reactome.org/PathwayBrowser/#/R-MMU-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 57540 R-MMU-9861626 https://reactome.org/PathwayBrowser/#/R-MMU-9861626 SIRT4 cleaves lipoyl from DLAT IEA Mus musculus 57540 R-MTU-879245 https://reactome.org/PathwayBrowser/#/R-MTU-879245 mycothiol binds formaldehyde and is dehydrogenated TAS Mycobacterium tuberculosis 57540 R-MTU-964914 https://reactome.org/PathwayBrowser/#/R-MTU-964914 DHQ from DAHP dephosphorylation TAS Mycobacterium tuberculosis 57540 R-OCU-2161568 https://reactome.org/PathwayBrowser/#/R-OCU-2161568 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD TAS Oryctolagus cuniculus 57540 R-PFA-1855178 https://reactome.org/PathwayBrowser/#/R-PFA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Plasmodium falciparum 57540 R-PFA-197271 https://reactome.org/PathwayBrowser/#/R-PFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Plasmodium falciparum 57540 R-PFA-204617 https://reactome.org/PathwayBrowser/#/R-PFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Plasmodium falciparum 57540 R-PFA-204647 https://reactome.org/PathwayBrowser/#/R-PFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Plasmodium falciparum 57540 R-PFA-204662 https://reactome.org/PathwayBrowser/#/R-PFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Plasmodium falciparum 57540 R-PFA-450971 https://reactome.org/PathwayBrowser/#/R-PFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Plasmodium falciparum 57540 R-PFA-5688294 https://reactome.org/PathwayBrowser/#/R-PFA-5688294 SIRT5 deacetylates Cytochrome C IEA Plasmodium falciparum 57540 R-PFA-5694018 https://reactome.org/PathwayBrowser/#/R-PFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Plasmodium falciparum 57540 R-PFA-5696655 https://reactome.org/PathwayBrowser/#/R-PFA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Plasmodium falciparum 57540 R-PFA-6783939 https://reactome.org/PathwayBrowser/#/R-PFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 57540 R-PFA-6801328 https://reactome.org/PathwayBrowser/#/R-PFA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Plasmodium falciparum 57540 R-PFA-70449 https://reactome.org/PathwayBrowser/#/R-PFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Plasmodium falciparum 57540 R-PFA-70482 https://reactome.org/PathwayBrowser/#/R-PFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Plasmodium falciparum 57540 R-PFA-70664 https://reactome.org/PathwayBrowser/#/R-PFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 57540 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 57540 R-PFA-70979 https://reactome.org/PathwayBrowser/#/R-PFA-70979 MDH2 dimer dehydrogenates MAL IEA Plasmodium falciparum 57540 R-PFA-73794 https://reactome.org/PathwayBrowser/#/R-PFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Plasmodium falciparum 57540 R-PFA-75889 https://reactome.org/PathwayBrowser/#/R-PFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Plasmodium falciparum 57540 R-PFA-8955030 https://reactome.org/PathwayBrowser/#/R-PFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Plasmodium falciparum 57540 R-PFA-9748945 https://reactome.org/PathwayBrowser/#/R-PFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Plasmodium falciparum 57540 R-PFA-9853499 https://reactome.org/PathwayBrowser/#/R-PFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Plasmodium falciparum 57540 R-RNO-109343 https://reactome.org/PathwayBrowser/#/R-RNO-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Rattus norvegicus 57540 R-RNO-1614362 https://reactome.org/PathwayBrowser/#/R-RNO-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Rattus norvegicus 57540 R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Rattus norvegicus 57540 R-RNO-173597 https://reactome.org/PathwayBrowser/#/R-RNO-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Rattus norvegicus 57540 R-RNO-174401 https://reactome.org/PathwayBrowser/#/R-RNO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Rattus norvegicus 57540 R-RNO-1855178 https://reactome.org/PathwayBrowser/#/R-RNO-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Rattus norvegicus 57540 R-RNO-192097 https://reactome.org/PathwayBrowser/#/R-RNO-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Rattus norvegicus 57540 R-RNO-193073 https://reactome.org/PathwayBrowser/#/R-RNO-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Rattus norvegicus 57540 R-RNO-193455 https://reactome.org/PathwayBrowser/#/R-RNO-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 57540 R-RNO-193508 https://reactome.org/PathwayBrowser/#/R-RNO-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 57540 R-RNO-193789 https://reactome.org/PathwayBrowser/#/R-RNO-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 57540 R-RNO-193816 https://reactome.org/PathwayBrowser/#/R-RNO-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Rattus norvegicus 57540 R-RNO-194642 https://reactome.org/PathwayBrowser/#/R-RNO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Rattus norvegicus 57540 R-RNO-194718 https://reactome.org/PathwayBrowser/#/R-RNO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Rattus norvegicus 57540 R-RNO-196350 https://reactome.org/PathwayBrowser/#/R-RNO-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Rattus norvegicus 57540 R-RNO-196372 https://reactome.org/PathwayBrowser/#/R-RNO-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Rattus norvegicus 57540 R-RNO-197198 https://reactome.org/PathwayBrowser/#/R-RNO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 57540 R-RNO-197271 https://reactome.org/PathwayBrowser/#/R-RNO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Rattus norvegicus 57540 R-RNO-198824 https://reactome.org/PathwayBrowser/#/R-RNO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Rattus norvegicus 57540 R-RNO-2046084 https://reactome.org/PathwayBrowser/#/R-RNO-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Rattus norvegicus 57540 R-RNO-2046089 https://reactome.org/PathwayBrowser/#/R-RNO-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Rattus norvegicus 57540 R-RNO-2046091 https://reactome.org/PathwayBrowser/#/R-RNO-2046091 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA TAS Rattus norvegicus 57540 R-RNO-2046092 https://reactome.org/PathwayBrowser/#/R-RNO-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Rattus norvegicus 57540 R-RNO-2046096 https://reactome.org/PathwayBrowser/#/R-RNO-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Rattus norvegicus 57540 R-RNO-2046097 https://reactome.org/PathwayBrowser/#/R-RNO-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 57540 R-RNO-204617 https://reactome.org/PathwayBrowser/#/R-RNO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Rattus norvegicus 57540 R-RNO-204647 https://reactome.org/PathwayBrowser/#/R-RNO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Rattus norvegicus 57540 R-RNO-204662 https://reactome.org/PathwayBrowser/#/R-RNO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Rattus norvegicus 57540 R-RNO-2161779 https://reactome.org/PathwayBrowser/#/R-RNO-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Rattus norvegicus 57540 R-RNO-2162078 https://reactome.org/PathwayBrowser/#/R-RNO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Rattus norvegicus 57540 R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 57540 R-RNO-2187325 https://reactome.org/PathwayBrowser/#/R-RNO-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Rattus norvegicus 57540 R-RNO-3371467 https://reactome.org/PathwayBrowser/#/R-RNO-3371467 SIRT1 deacetylates HSF1 IEA Rattus norvegicus 57540 R-RNO-3640858 https://reactome.org/PathwayBrowser/#/R-RNO-3640858 Tankyrase ADP-ribosylates AXIN IEA Rattus norvegicus 57540 R-RNO-380608 https://reactome.org/PathwayBrowser/#/R-RNO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Rattus norvegicus 57540 R-RNO-389609 https://reactome.org/PathwayBrowser/#/R-RNO-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Rattus norvegicus 57540 R-RNO-389995 https://reactome.org/PathwayBrowser/#/R-RNO-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Rattus norvegicus 57540 R-RNO-390251 https://reactome.org/PathwayBrowser/#/R-RNO-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 57540 R-RNO-427514 https://reactome.org/PathwayBrowser/#/R-RNO-427514 eNoSC deacetylates histone H3 IEA Rattus norvegicus 57540 R-RNO-450971 https://reactome.org/PathwayBrowser/#/R-RNO-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Rattus norvegicus 57540 R-RNO-508369 https://reactome.org/PathwayBrowser/#/R-RNO-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Rattus norvegicus 57540 R-RNO-508473 https://reactome.org/PathwayBrowser/#/R-RNO-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Rattus norvegicus 57540 R-RNO-5226904 https://reactome.org/PathwayBrowser/#/R-RNO-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Rattus norvegicus 57540 R-RNO-5362518 https://reactome.org/PathwayBrowser/#/R-RNO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Rattus norvegicus 57540 R-RNO-5362522 https://reactome.org/PathwayBrowser/#/R-RNO-5362522 ALDHs oxidise atRAL to atRA IEA Rattus norvegicus 57540 R-RNO-5362564 https://reactome.org/PathwayBrowser/#/R-RNO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Rattus norvegicus 57540 R-RNO-5362721 https://reactome.org/PathwayBrowser/#/R-RNO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 57540 R-RNO-5651723 https://reactome.org/PathwayBrowser/#/R-RNO-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Rattus norvegicus 57540 R-RNO-5652195 https://reactome.org/PathwayBrowser/#/R-RNO-5652195 SORD oxidizes D-sorbitol to Fru IEA Rattus norvegicus 57540 R-RNO-5661290 https://reactome.org/PathwayBrowser/#/R-RNO-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Rattus norvegicus 57540 R-RNO-5662471 https://reactome.org/PathwayBrowser/#/R-RNO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Rattus norvegicus 57540 R-RNO-5685953 https://reactome.org/PathwayBrowser/#/R-RNO-5685953 SIRT6 deacetylates RBBP8 IEA Rattus norvegicus 57540 R-RNO-5687653 https://reactome.org/PathwayBrowser/#/R-RNO-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Rattus norvegicus 57540 R-RNO-5688276 https://reactome.org/PathwayBrowser/#/R-RNO-5688276 SIRT4 transfers ADPRib to GLUD IEA Rattus norvegicus 57540 R-RNO-5688289 https://reactome.org/PathwayBrowser/#/R-RNO-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Rattus norvegicus 57540 R-RNO-5688294 https://reactome.org/PathwayBrowser/#/R-RNO-5688294 SIRT5 deacetylates Cytochrome C IEA Rattus norvegicus 57540 R-RNO-5692237 https://reactome.org/PathwayBrowser/#/R-RNO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Rattus norvegicus 57540 R-RNO-5692261 https://reactome.org/PathwayBrowser/#/R-RNO-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Rattus norvegicus 57540 R-RNO-5694018 https://reactome.org/PathwayBrowser/#/R-RNO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Rattus norvegicus 57540 R-RNO-5696080 https://reactome.org/PathwayBrowser/#/R-RNO-5696080 ALDH3B1 oxidises HXAL to PALM IEA Rattus norvegicus 57540 R-RNO-5696091 https://reactome.org/PathwayBrowser/#/R-RNO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Rattus norvegicus 57540 R-RNO-5696101 https://reactome.org/PathwayBrowser/#/R-RNO-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Rattus norvegicus 57540 R-RNO-5696457 https://reactome.org/PathwayBrowser/#/R-RNO-5696457 BDH2 dehydrogenates 3HBA IEA Rattus norvegicus 57540 R-RNO-5696655 https://reactome.org/PathwayBrowser/#/R-RNO-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Rattus norvegicus 57540 R-RNO-6783939 https://reactome.org/PathwayBrowser/#/R-RNO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 57540 R-RNO-6784399 https://reactome.org/PathwayBrowser/#/R-RNO-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Rattus norvegicus 57540 R-RNO-6797955 https://reactome.org/PathwayBrowser/#/R-RNO-6797955 ALDH7A1 oxidises BETALD to BET IEA Rattus norvegicus 57540 R-RNO-6801328 https://reactome.org/PathwayBrowser/#/R-RNO-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Rattus norvegicus 57540 R-RNO-6806831 https://reactome.org/PathwayBrowser/#/R-RNO-6806831 CYB5Rs reduce MetHb to HbA IEA Rattus norvegicus 57540 R-RNO-6807826 https://reactome.org/PathwayBrowser/#/R-RNO-6807826 LDHAL6B reduces PYR to LACT IEA Rattus norvegicus 57540 R-RNO-6808464 https://reactome.org/PathwayBrowser/#/R-RNO-6808464 ALDH3B2 oxidises HXAL to PALM IEA Rattus norvegicus 57540 R-RNO-6809264 https://reactome.org/PathwayBrowser/#/R-RNO-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 57540 R-RNO-6813749 https://reactome.org/PathwayBrowser/#/R-RNO-6813749 ALDH1A1 oxidises GA to DGA IEA Rattus norvegicus 57540 R-RNO-70369 https://reactome.org/PathwayBrowser/#/R-RNO-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Rattus norvegicus 57540 R-RNO-70449 https://reactome.org/PathwayBrowser/#/R-RNO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Rattus norvegicus 57540 R-RNO-70482 https://reactome.org/PathwayBrowser/#/R-RNO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Rattus norvegicus 57540 R-RNO-70510 https://reactome.org/PathwayBrowser/#/R-RNO-70510 LDH tetramer oxidises LACT to PYR IEA Rattus norvegicus 57540 R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Rattus norvegicus 57540 R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Rattus norvegicus 57540 R-RNO-70664 https://reactome.org/PathwayBrowser/#/R-RNO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 57540 R-RNO-70679 https://reactome.org/PathwayBrowser/#/R-RNO-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Rattus norvegicus 57540 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 57540 R-RNO-70837 https://reactome.org/PathwayBrowser/#/R-RNO-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Rattus norvegicus 57540 R-RNO-70885 https://reactome.org/PathwayBrowser/#/R-RNO-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Rattus norvegicus 57540 R-RNO-70893 https://reactome.org/PathwayBrowser/#/R-RNO-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 57540 R-RNO-70903 https://reactome.org/PathwayBrowser/#/R-RNO-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Rattus norvegicus 57540 R-RNO-70940 https://reactome.org/PathwayBrowser/#/R-RNO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Rattus norvegicus 57540 R-RNO-70941 https://reactome.org/PathwayBrowser/#/R-RNO-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Rattus norvegicus 57540 R-RNO-70967 https://reactome.org/PathwayBrowser/#/R-RNO-70967 IDH3 complex decarboxylates isocitrate IEA Rattus norvegicus 57540 R-RNO-70979 https://reactome.org/PathwayBrowser/#/R-RNO-70979 MDH2 dimer dehydrogenates MAL IEA Rattus norvegicus 57540 R-RNO-71037 https://reactome.org/PathwayBrowser/#/R-RNO-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 57540 R-RNO-71130 https://reactome.org/PathwayBrowser/#/R-RNO-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Rattus norvegicus 57540 R-RNO-71260 https://reactome.org/PathwayBrowser/#/R-RNO-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Rattus norvegicus 57540 R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 57540 R-RNO-71707 https://reactome.org/PathwayBrowser/#/R-RNO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Rattus norvegicus 57540 R-RNO-71723 https://reactome.org/PathwayBrowser/#/R-RNO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Rattus norvegicus 57540 R-RNO-71849 https://reactome.org/PathwayBrowser/#/R-RNO-71849 LDH tetramer reduces PYR to LACT IEA Rattus norvegicus 57540 R-RNO-73794 https://reactome.org/PathwayBrowser/#/R-RNO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Rattus norvegicus 57540 R-RNO-73912 https://reactome.org/PathwayBrowser/#/R-RNO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Rattus norvegicus 57540 R-RNO-73920 https://reactome.org/PathwayBrowser/#/R-RNO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Rattus norvegicus 57540 R-RNO-75889 https://reactome.org/PathwayBrowser/#/R-RNO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Rattus norvegicus 57540 R-RNO-77254 https://reactome.org/PathwayBrowser/#/R-RNO-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Rattus norvegicus 57540 R-RNO-77283 https://reactome.org/PathwayBrowser/#/R-RNO-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Rattus norvegicus 57540 R-RNO-77303 https://reactome.org/PathwayBrowser/#/R-RNO-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Rattus norvegicus 57540 R-RNO-77312 https://reactome.org/PathwayBrowser/#/R-RNO-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Rattus norvegicus 57540 R-RNO-77323 https://reactome.org/PathwayBrowser/#/R-RNO-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Rattus norvegicus 57540 R-RNO-77331 https://reactome.org/PathwayBrowser/#/R-RNO-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Rattus norvegicus 57540 R-RNO-77342 https://reactome.org/PathwayBrowser/#/R-RNO-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Rattus norvegicus 57540 R-RNO-8870346 https://reactome.org/PathwayBrowser/#/R-RNO-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Rattus norvegicus 57540 R-RNO-888548 https://reactome.org/PathwayBrowser/#/R-RNO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Rattus norvegicus 57540 R-RNO-8936442 https://reactome.org/PathwayBrowser/#/R-RNO-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Rattus norvegicus 57540 R-RNO-8938073 https://reactome.org/PathwayBrowser/#/R-RNO-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Rattus norvegicus 57540 R-RNO-8938076 https://reactome.org/PathwayBrowser/#/R-RNO-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Rattus norvegicus 57540 R-RNO-8939959 https://reactome.org/PathwayBrowser/#/R-RNO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Rattus norvegicus 57540 R-RNO-8940070 https://reactome.org/PathwayBrowser/#/R-RNO-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Rattus norvegicus 57540 R-RNO-8948800 https://reactome.org/PathwayBrowser/#/R-RNO-8948800 TNKS and TNKS2 PARylate PTEN IEA Rattus norvegicus 57540 R-RNO-8955030 https://reactome.org/PathwayBrowser/#/R-RNO-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 57540 R-RNO-8956458 https://reactome.org/PathwayBrowser/#/R-RNO-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Rattus norvegicus 57540 R-RNO-9012268 https://reactome.org/PathwayBrowser/#/R-RNO-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 57540 R-RNO-9023968 https://reactome.org/PathwayBrowser/#/R-RNO-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Rattus norvegicus 57540 R-RNO-9024766 https://reactome.org/PathwayBrowser/#/R-RNO-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Rattus norvegicus 57540 R-RNO-9620532 https://reactome.org/PathwayBrowser/#/R-RNO-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Rattus norvegicus 57540 R-RNO-9667952 https://reactome.org/PathwayBrowser/#/R-RNO-9667952 ANKLE2 is deacetylated by SIRT2 IEA Rattus norvegicus 57540 R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 57540 R-RNO-9727349 https://reactome.org/PathwayBrowser/#/R-RNO-9727349 XDH dehydrogenates xanthine to form urate IEA Rattus norvegicus 57540 R-RNO-9748945 https://reactome.org/PathwayBrowser/#/R-RNO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Rattus norvegicus 57540 R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 57540 R-RNO-9759549 https://reactome.org/PathwayBrowser/#/R-RNO-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Rattus norvegicus 57540 R-RNO-977348 https://reactome.org/PathwayBrowser/#/R-RNO-977348 PHGDH tetramer dehydrogenates 3PG IEA Rattus norvegicus 57540 R-RNO-9853499 https://reactome.org/PathwayBrowser/#/R-RNO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 57540 R-RNO-9854463 https://reactome.org/PathwayBrowser/#/R-RNO-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Rattus norvegicus 57540 R-RNO-9856871 https://reactome.org/PathwayBrowser/#/R-RNO-9856871 MDH1 reduces OA IEA Rattus norvegicus 57540 R-RNO-9861616 https://reactome.org/PathwayBrowser/#/R-RNO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 57540 R-RNO-9861626 https://reactome.org/PathwayBrowser/#/R-RNO-9861626 SIRT4 cleaves lipoyl from DLAT IEA Rattus norvegicus 57540 R-SCE-174401 https://reactome.org/PathwayBrowser/#/R-SCE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Saccharomyces cerevisiae 57540 R-SCE-1855178 https://reactome.org/PathwayBrowser/#/R-SCE-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Saccharomyces cerevisiae 57540 R-SCE-194642 https://reactome.org/PathwayBrowser/#/R-SCE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Saccharomyces cerevisiae 57540 R-SCE-194718 https://reactome.org/PathwayBrowser/#/R-SCE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Saccharomyces cerevisiae 57540 R-SCE-197198 https://reactome.org/PathwayBrowser/#/R-SCE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Saccharomyces cerevisiae 57540 R-SCE-197271 https://reactome.org/PathwayBrowser/#/R-SCE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Saccharomyces cerevisiae 57540 R-SCE-198824 https://reactome.org/PathwayBrowser/#/R-SCE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Saccharomyces cerevisiae 57540 R-SCE-204617 https://reactome.org/PathwayBrowser/#/R-SCE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Saccharomyces cerevisiae 57540 R-SCE-204647 https://reactome.org/PathwayBrowser/#/R-SCE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Saccharomyces cerevisiae 57540 R-SCE-204662 https://reactome.org/PathwayBrowser/#/R-SCE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Saccharomyces cerevisiae 57540 R-SCE-2162078 https://reactome.org/PathwayBrowser/#/R-SCE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Saccharomyces cerevisiae 57540 R-SCE-2162194 https://reactome.org/PathwayBrowser/#/R-SCE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Saccharomyces cerevisiae 57540 R-SCE-380608 https://reactome.org/PathwayBrowser/#/R-SCE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Saccharomyces cerevisiae 57540 R-SCE-389609 https://reactome.org/PathwayBrowser/#/R-SCE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Saccharomyces cerevisiae 57540 R-SCE-427514 https://reactome.org/PathwayBrowser/#/R-SCE-427514 eNoSC deacetylates histone H3 IEA Saccharomyces cerevisiae 57540 R-SCE-5362518 https://reactome.org/PathwayBrowser/#/R-SCE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Saccharomyces cerevisiae 57540 R-SCE-5362522 https://reactome.org/PathwayBrowser/#/R-SCE-5362522 ALDHs oxidise atRAL to atRA IEA Saccharomyces cerevisiae 57540 R-SCE-5362564 https://reactome.org/PathwayBrowser/#/R-SCE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Saccharomyces cerevisiae 57540 R-SCE-5652195 https://reactome.org/PathwayBrowser/#/R-SCE-5652195 SORD oxidizes D-sorbitol to Fru IEA Saccharomyces cerevisiae 57540 R-SCE-5662471 https://reactome.org/PathwayBrowser/#/R-SCE-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Saccharomyces cerevisiae 57540 R-SCE-5688289 https://reactome.org/PathwayBrowser/#/R-SCE-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Saccharomyces cerevisiae 57540 R-SCE-5692237 https://reactome.org/PathwayBrowser/#/R-SCE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Saccharomyces cerevisiae 57540 R-SCE-5692261 https://reactome.org/PathwayBrowser/#/R-SCE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Saccharomyces cerevisiae 57540 R-SCE-5694018 https://reactome.org/PathwayBrowser/#/R-SCE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Saccharomyces cerevisiae 57540 R-SCE-5696080 https://reactome.org/PathwayBrowser/#/R-SCE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 57540 R-SCE-5696091 https://reactome.org/PathwayBrowser/#/R-SCE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Saccharomyces cerevisiae 57540 R-SCE-6783939 https://reactome.org/PathwayBrowser/#/R-SCE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 57540 R-SCE-6790127 https://reactome.org/PathwayBrowser/#/R-SCE-6790127 SMM1 (DUS2) reduces uridine-20 to dihydrouridine in tRNA(Leu) TAS Saccharomyces cerevisiae 57540 R-SCE-6801328 https://reactome.org/PathwayBrowser/#/R-SCE-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Saccharomyces cerevisiae 57540 R-SCE-6808464 https://reactome.org/PathwayBrowser/#/R-SCE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 57540 R-SCE-6813749 https://reactome.org/PathwayBrowser/#/R-SCE-6813749 ALDH1A1 oxidises GA to DGA IEA Saccharomyces cerevisiae 57540 R-SCE-70369 https://reactome.org/PathwayBrowser/#/R-SCE-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Saccharomyces cerevisiae 57540 R-SCE-70449 https://reactome.org/PathwayBrowser/#/R-SCE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Saccharomyces cerevisiae 57540 R-SCE-70482 https://reactome.org/PathwayBrowser/#/R-SCE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Saccharomyces cerevisiae 57540 R-SCE-70664 https://reactome.org/PathwayBrowser/#/R-SCE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 57540 R-SCE-70940 https://reactome.org/PathwayBrowser/#/R-SCE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Saccharomyces cerevisiae 57540 R-SCE-70967 https://reactome.org/PathwayBrowser/#/R-SCE-70967 IDH3 complex decarboxylates isocitrate IEA Saccharomyces cerevisiae 57540 R-SCE-70979 https://reactome.org/PathwayBrowser/#/R-SCE-70979 MDH2 dimer dehydrogenates MAL IEA Saccharomyces cerevisiae 57540 R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 57540 R-SCE-71707 https://reactome.org/PathwayBrowser/#/R-SCE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Saccharomyces cerevisiae 57540 R-SCE-71723 https://reactome.org/PathwayBrowser/#/R-SCE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Saccharomyces cerevisiae 57540 R-SCE-73794 https://reactome.org/PathwayBrowser/#/R-SCE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Saccharomyces cerevisiae 57540 R-SCE-75889 https://reactome.org/PathwayBrowser/#/R-SCE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Saccharomyces cerevisiae 57540 R-SCE-888548 https://reactome.org/PathwayBrowser/#/R-SCE-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Saccharomyces cerevisiae 57540 R-SCE-8939959 https://reactome.org/PathwayBrowser/#/R-SCE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Saccharomyces cerevisiae 57540 R-SCE-9748945 https://reactome.org/PathwayBrowser/#/R-SCE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Saccharomyces cerevisiae 57540 R-SCE-9853499 https://reactome.org/PathwayBrowser/#/R-SCE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 57540 R-SCE-9861616 https://reactome.org/PathwayBrowser/#/R-SCE-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 57540 R-SPO-174401 https://reactome.org/PathwayBrowser/#/R-SPO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Schizosaccharomyces pombe 57540 R-SPO-194642 https://reactome.org/PathwayBrowser/#/R-SPO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Schizosaccharomyces pombe 57540 R-SPO-194718 https://reactome.org/PathwayBrowser/#/R-SPO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Schizosaccharomyces pombe 57540 R-SPO-197198 https://reactome.org/PathwayBrowser/#/R-SPO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Schizosaccharomyces pombe 57540 R-SPO-197271 https://reactome.org/PathwayBrowser/#/R-SPO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Schizosaccharomyces pombe 57540 R-SPO-198824 https://reactome.org/PathwayBrowser/#/R-SPO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Schizosaccharomyces pombe 57540 R-SPO-204617 https://reactome.org/PathwayBrowser/#/R-SPO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Schizosaccharomyces pombe 57540 R-SPO-204647 https://reactome.org/PathwayBrowser/#/R-SPO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Schizosaccharomyces pombe 57540 R-SPO-204662 https://reactome.org/PathwayBrowser/#/R-SPO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Schizosaccharomyces pombe 57540 R-SPO-2162078 https://reactome.org/PathwayBrowser/#/R-SPO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Schizosaccharomyces pombe 57540 R-SPO-2162194 https://reactome.org/PathwayBrowser/#/R-SPO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Schizosaccharomyces pombe 57540 R-SPO-380608 https://reactome.org/PathwayBrowser/#/R-SPO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Schizosaccharomyces pombe 57540 R-SPO-427514 https://reactome.org/PathwayBrowser/#/R-SPO-427514 eNoSC deacetylates histone H3 IEA Schizosaccharomyces pombe 57540 R-SPO-5362518 https://reactome.org/PathwayBrowser/#/R-SPO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Schizosaccharomyces pombe 57540 R-SPO-5362522 https://reactome.org/PathwayBrowser/#/R-SPO-5362522 ALDHs oxidise atRAL to atRA IEA Schizosaccharomyces pombe 57540 R-SPO-5362564 https://reactome.org/PathwayBrowser/#/R-SPO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Schizosaccharomyces pombe 57540 R-SPO-5362721 https://reactome.org/PathwayBrowser/#/R-SPO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Schizosaccharomyces pombe 57540 R-SPO-5652195 https://reactome.org/PathwayBrowser/#/R-SPO-5652195 SORD oxidizes D-sorbitol to Fru IEA Schizosaccharomyces pombe 57540 R-SPO-5662471 https://reactome.org/PathwayBrowser/#/R-SPO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Schizosaccharomyces pombe 57540 R-SPO-5688289 https://reactome.org/PathwayBrowser/#/R-SPO-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Schizosaccharomyces pombe 57540 R-SPO-5692237 https://reactome.org/PathwayBrowser/#/R-SPO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Schizosaccharomyces pombe 57540 R-SPO-5694018 https://reactome.org/PathwayBrowser/#/R-SPO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Schizosaccharomyces pombe 57540 R-SPO-5696091 https://reactome.org/PathwayBrowser/#/R-SPO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Schizosaccharomyces pombe 57540 R-SPO-6783939 https://reactome.org/PathwayBrowser/#/R-SPO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 57540 R-SPO-6801328 https://reactome.org/PathwayBrowser/#/R-SPO-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Schizosaccharomyces pombe 57540 R-SPO-6813749 https://reactome.org/PathwayBrowser/#/R-SPO-6813749 ALDH1A1 oxidises GA to DGA IEA Schizosaccharomyces pombe 57540 R-SPO-70369 https://reactome.org/PathwayBrowser/#/R-SPO-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Schizosaccharomyces pombe 57540 R-SPO-70449 https://reactome.org/PathwayBrowser/#/R-SPO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Schizosaccharomyces pombe 57540 R-SPO-70482 https://reactome.org/PathwayBrowser/#/R-SPO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Schizosaccharomyces pombe 57540 R-SPO-70664 https://reactome.org/PathwayBrowser/#/R-SPO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 57540 R-SPO-70940 https://reactome.org/PathwayBrowser/#/R-SPO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Schizosaccharomyces pombe 57540 R-SPO-70967 https://reactome.org/PathwayBrowser/#/R-SPO-70967 IDH3 complex decarboxylates isocitrate IEA Schizosaccharomyces pombe 57540 R-SPO-70979 https://reactome.org/PathwayBrowser/#/R-SPO-70979 MDH2 dimer dehydrogenates MAL IEA Schizosaccharomyces pombe 57540 R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 57540 R-SPO-71707 https://reactome.org/PathwayBrowser/#/R-SPO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Schizosaccharomyces pombe 57540 R-SPO-71723 https://reactome.org/PathwayBrowser/#/R-SPO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Schizosaccharomyces pombe 57540 R-SPO-73794 https://reactome.org/PathwayBrowser/#/R-SPO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Schizosaccharomyces pombe 57540 R-SPO-73912 https://reactome.org/PathwayBrowser/#/R-SPO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Schizosaccharomyces pombe 57540 R-SPO-73920 https://reactome.org/PathwayBrowser/#/R-SPO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Schizosaccharomyces pombe 57540 R-SPO-75889 https://reactome.org/PathwayBrowser/#/R-SPO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Schizosaccharomyces pombe 57540 R-SPO-888548 https://reactome.org/PathwayBrowser/#/R-SPO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Schizosaccharomyces pombe 57540 R-SPO-8939959 https://reactome.org/PathwayBrowser/#/R-SPO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Schizosaccharomyces pombe 57540 R-SPO-9748945 https://reactome.org/PathwayBrowser/#/R-SPO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Schizosaccharomyces pombe 57540 R-SPO-9853499 https://reactome.org/PathwayBrowser/#/R-SPO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 57540 R-SPO-9861616 https://reactome.org/PathwayBrowser/#/R-SPO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 57540 R-SSC-109343 https://reactome.org/PathwayBrowser/#/R-SSC-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Sus scrofa 57540 R-SSC-1614362 https://reactome.org/PathwayBrowser/#/R-SSC-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Sus scrofa 57540 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Sus scrofa 57540 R-SSC-173597 https://reactome.org/PathwayBrowser/#/R-SSC-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Sus scrofa 57540 R-SSC-174401 https://reactome.org/PathwayBrowser/#/R-SSC-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Sus scrofa 57540 R-SSC-1855178 https://reactome.org/PathwayBrowser/#/R-SSC-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Sus scrofa 57540 R-SSC-192097 https://reactome.org/PathwayBrowser/#/R-SSC-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Sus scrofa 57540 R-SSC-193073 https://reactome.org/PathwayBrowser/#/R-SSC-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Sus scrofa 57540 R-SSC-193789 https://reactome.org/PathwayBrowser/#/R-SSC-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Sus scrofa 57540 R-SSC-193816 https://reactome.org/PathwayBrowser/#/R-SSC-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Sus scrofa 57540 R-SSC-194642 https://reactome.org/PathwayBrowser/#/R-SSC-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Sus scrofa 57540 R-SSC-194718 https://reactome.org/PathwayBrowser/#/R-SSC-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Sus scrofa 57540 R-SSC-196350 https://reactome.org/PathwayBrowser/#/R-SSC-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Sus scrofa 57540 R-SSC-196372 https://reactome.org/PathwayBrowser/#/R-SSC-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Sus scrofa 57540 R-SSC-197198 https://reactome.org/PathwayBrowser/#/R-SSC-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Sus scrofa 57540 R-SSC-197271 https://reactome.org/PathwayBrowser/#/R-SSC-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Sus scrofa 57540 R-SSC-198824 https://reactome.org/PathwayBrowser/#/R-SSC-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Sus scrofa 57540 R-SSC-2046084 https://reactome.org/PathwayBrowser/#/R-SSC-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Sus scrofa 57540 R-SSC-2046089 https://reactome.org/PathwayBrowser/#/R-SSC-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Sus scrofa 57540 R-SSC-2046092 https://reactome.org/PathwayBrowser/#/R-SSC-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Sus scrofa 57540 R-SSC-2046096 https://reactome.org/PathwayBrowser/#/R-SSC-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Sus scrofa 57540 R-SSC-2046097 https://reactome.org/PathwayBrowser/#/R-SSC-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 57540 R-SSC-204617 https://reactome.org/PathwayBrowser/#/R-SSC-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Sus scrofa 57540 R-SSC-204647 https://reactome.org/PathwayBrowser/#/R-SSC-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Sus scrofa 57540 R-SSC-204662 https://reactome.org/PathwayBrowser/#/R-SSC-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Sus scrofa 57540 R-SSC-2161779 https://reactome.org/PathwayBrowser/#/R-SSC-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Sus scrofa 57540 R-SSC-2162078 https://reactome.org/PathwayBrowser/#/R-SSC-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Sus scrofa 57540 R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa 57540 R-SSC-2187325 https://reactome.org/PathwayBrowser/#/R-SSC-2187325 PARP1 ADP-ribosylates SMAD3 and SMAD4 IEA Sus scrofa 57540 R-SSC-2454081 https://reactome.org/PathwayBrowser/#/R-SSC-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Sus scrofa 57540 R-SSC-3371467 https://reactome.org/PathwayBrowser/#/R-SSC-3371467 SIRT1 deacetylates HSF1 IEA Sus scrofa 57540 R-SSC-3640858 https://reactome.org/PathwayBrowser/#/R-SSC-3640858 Tankyrase ADP-ribosylates AXIN IEA Sus scrofa 57540 R-SSC-380608 https://reactome.org/PathwayBrowser/#/R-SSC-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Sus scrofa 57540 R-SSC-389609 https://reactome.org/PathwayBrowser/#/R-SSC-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Sus scrofa 57540 R-SSC-427514 https://reactome.org/PathwayBrowser/#/R-SSC-427514 eNoSC deacetylates histone H3 IEA Sus scrofa 57540 R-SSC-508369 https://reactome.org/PathwayBrowser/#/R-SSC-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Sus scrofa 57540 R-SSC-508473 https://reactome.org/PathwayBrowser/#/R-SSC-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Sus scrofa 57540 R-SSC-5226904 https://reactome.org/PathwayBrowser/#/R-SSC-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Sus scrofa 57540 R-SSC-5362518 https://reactome.org/PathwayBrowser/#/R-SSC-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Sus scrofa 57540 R-SSC-5362522 https://reactome.org/PathwayBrowser/#/R-SSC-5362522 ALDHs oxidise atRAL to atRA IEA Sus scrofa 57540 R-SSC-5362564 https://reactome.org/PathwayBrowser/#/R-SSC-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Sus scrofa 57540 R-SSC-5362721 https://reactome.org/PathwayBrowser/#/R-SSC-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Sus scrofa 57540 R-SSC-5651723 https://reactome.org/PathwayBrowser/#/R-SSC-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Sus scrofa 57540 R-SSC-5652195 https://reactome.org/PathwayBrowser/#/R-SSC-5652195 SORD oxidizes D-sorbitol to Fru IEA Sus scrofa 57540 R-SSC-5661290 https://reactome.org/PathwayBrowser/#/R-SSC-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Sus scrofa 57540 R-SSC-5662471 https://reactome.org/PathwayBrowser/#/R-SSC-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Sus scrofa 57540 R-SSC-5685953 https://reactome.org/PathwayBrowser/#/R-SSC-5685953 SIRT6 deacetylates RBBP8 IEA Sus scrofa 57540 R-SSC-5687653 https://reactome.org/PathwayBrowser/#/R-SSC-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Sus scrofa 57540 R-SSC-5688276 https://reactome.org/PathwayBrowser/#/R-SSC-5688276 SIRT4 transfers ADPRib to GLUD IEA Sus scrofa 57540 R-SSC-5688289 https://reactome.org/PathwayBrowser/#/R-SSC-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Sus scrofa 57540 R-SSC-5688294 https://reactome.org/PathwayBrowser/#/R-SSC-5688294 SIRT5 deacetylates Cytochrome C IEA Sus scrofa 57540 R-SSC-5692237 https://reactome.org/PathwayBrowser/#/R-SSC-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Sus scrofa 57540 R-SSC-5692261 https://reactome.org/PathwayBrowser/#/R-SSC-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Sus scrofa 57540 R-SSC-5694018 https://reactome.org/PathwayBrowser/#/R-SSC-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Sus scrofa 57540 R-SSC-5696080 https://reactome.org/PathwayBrowser/#/R-SSC-5696080 ALDH3B1 oxidises HXAL to PALM IEA Sus scrofa 57540 R-SSC-5696091 https://reactome.org/PathwayBrowser/#/R-SSC-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Sus scrofa 57540 R-SSC-5696101 https://reactome.org/PathwayBrowser/#/R-SSC-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Sus scrofa 57540 R-SSC-5696457 https://reactome.org/PathwayBrowser/#/R-SSC-5696457 BDH2 dehydrogenates 3HBA IEA Sus scrofa 57540 R-SSC-5696655 https://reactome.org/PathwayBrowser/#/R-SSC-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Sus scrofa 57540 R-SSC-6783939 https://reactome.org/PathwayBrowser/#/R-SSC-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 57540 R-SSC-6784399 https://reactome.org/PathwayBrowser/#/R-SSC-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Sus scrofa 57540 R-SSC-6797955 https://reactome.org/PathwayBrowser/#/R-SSC-6797955 ALDH7A1 oxidises BETALD to BET IEA Sus scrofa 57540 R-SSC-6801328 https://reactome.org/PathwayBrowser/#/R-SSC-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Sus scrofa 57540 R-SSC-6806831 https://reactome.org/PathwayBrowser/#/R-SSC-6806831 CYB5Rs reduce MetHb to HbA IEA Sus scrofa 57540 R-SSC-6808464 https://reactome.org/PathwayBrowser/#/R-SSC-6808464 ALDH3B2 oxidises HXAL to PALM IEA Sus scrofa 57540 R-SSC-6809264 https://reactome.org/PathwayBrowser/#/R-SSC-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Sus scrofa 57540 R-SSC-6813749 https://reactome.org/PathwayBrowser/#/R-SSC-6813749 ALDH1A1 oxidises GA to DGA IEA Sus scrofa 57540 R-SSC-70369 https://reactome.org/PathwayBrowser/#/R-SSC-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Sus scrofa 57540 R-SSC-70449 https://reactome.org/PathwayBrowser/#/R-SSC-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Sus scrofa 57540 R-SSC-70482 https://reactome.org/PathwayBrowser/#/R-SSC-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Sus scrofa 57540 R-SSC-70510 https://reactome.org/PathwayBrowser/#/R-SSC-70510 LDH tetramer oxidises LACT to PYR IEA Sus scrofa 57540 R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Sus scrofa 57540 R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Sus scrofa 57540 R-SSC-70664 https://reactome.org/PathwayBrowser/#/R-SSC-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 57540 R-SSC-70679 https://reactome.org/PathwayBrowser/#/R-SSC-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Sus scrofa 57540 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 57540 R-SSC-70837 https://reactome.org/PathwayBrowser/#/R-SSC-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Sus scrofa 57540 R-SSC-70885 https://reactome.org/PathwayBrowser/#/R-SSC-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Sus scrofa 57540 R-SSC-70893 https://reactome.org/PathwayBrowser/#/R-SSC-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Sus scrofa 57540 R-SSC-70903 https://reactome.org/PathwayBrowser/#/R-SSC-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Sus scrofa 57540 R-SSC-70940 https://reactome.org/PathwayBrowser/#/R-SSC-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Sus scrofa 57540 R-SSC-70941 https://reactome.org/PathwayBrowser/#/R-SSC-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Sus scrofa 57540 R-SSC-70967 https://reactome.org/PathwayBrowser/#/R-SSC-70967 IDH3 complex decarboxylates isocitrate IEA Sus scrofa 57540 R-SSC-70979 https://reactome.org/PathwayBrowser/#/R-SSC-70979 MDH2 dimer dehydrogenates MAL IEA Sus scrofa 57540 R-SSC-71037 https://reactome.org/PathwayBrowser/#/R-SSC-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Sus scrofa 57540 R-SSC-71130 https://reactome.org/PathwayBrowser/#/R-SSC-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Sus scrofa 57540 R-SSC-71260 https://reactome.org/PathwayBrowser/#/R-SSC-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Sus scrofa 57540 R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 57540 R-SSC-71707 https://reactome.org/PathwayBrowser/#/R-SSC-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Sus scrofa 57540 R-SSC-71723 https://reactome.org/PathwayBrowser/#/R-SSC-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Sus scrofa 57540 R-SSC-71849 https://reactome.org/PathwayBrowser/#/R-SSC-71849 LDH tetramer reduces PYR to LACT IEA Sus scrofa 57540 R-SSC-73794 https://reactome.org/PathwayBrowser/#/R-SSC-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Sus scrofa 57540 R-SSC-73912 https://reactome.org/PathwayBrowser/#/R-SSC-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Sus scrofa 57540 R-SSC-73920 https://reactome.org/PathwayBrowser/#/R-SSC-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Sus scrofa 57540 R-SSC-75889 https://reactome.org/PathwayBrowser/#/R-SSC-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Sus scrofa 57540 R-SSC-77254 https://reactome.org/PathwayBrowser/#/R-SSC-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Sus scrofa 57540 R-SSC-77283 https://reactome.org/PathwayBrowser/#/R-SSC-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Sus scrofa 57540 R-SSC-77303 https://reactome.org/PathwayBrowser/#/R-SSC-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Sus scrofa 57540 R-SSC-77312 https://reactome.org/PathwayBrowser/#/R-SSC-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Sus scrofa 57540 R-SSC-77323 https://reactome.org/PathwayBrowser/#/R-SSC-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Sus scrofa 57540 R-SSC-77331 https://reactome.org/PathwayBrowser/#/R-SSC-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Sus scrofa 57540 R-SSC-77342 https://reactome.org/PathwayBrowser/#/R-SSC-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Sus scrofa 57540 R-SSC-8870346 https://reactome.org/PathwayBrowser/#/R-SSC-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Sus scrofa 57540 R-SSC-888548 https://reactome.org/PathwayBrowser/#/R-SSC-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Sus scrofa 57540 R-SSC-8936442 https://reactome.org/PathwayBrowser/#/R-SSC-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Sus scrofa 57540 R-SSC-8938073 https://reactome.org/PathwayBrowser/#/R-SSC-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Sus scrofa 57540 R-SSC-8938076 https://reactome.org/PathwayBrowser/#/R-SSC-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Sus scrofa 57540 R-SSC-8939959 https://reactome.org/PathwayBrowser/#/R-SSC-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Sus scrofa 57540 R-SSC-8940070 https://reactome.org/PathwayBrowser/#/R-SSC-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Sus scrofa 57540 R-SSC-8948800 https://reactome.org/PathwayBrowser/#/R-SSC-8948800 TNKS and TNKS2 PARylate PTEN IEA Sus scrofa 57540 R-SSC-8955030 https://reactome.org/PathwayBrowser/#/R-SSC-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Sus scrofa 57540 R-SSC-8956458 https://reactome.org/PathwayBrowser/#/R-SSC-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Sus scrofa 57540 R-SSC-9012268 https://reactome.org/PathwayBrowser/#/R-SSC-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Sus scrofa 57540 R-SSC-9023968 https://reactome.org/PathwayBrowser/#/R-SSC-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Sus scrofa 57540 R-SSC-9024766 https://reactome.org/PathwayBrowser/#/R-SSC-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Sus scrofa 57540 R-SSC-9620532 https://reactome.org/PathwayBrowser/#/R-SSC-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Sus scrofa 57540 R-SSC-9667952 https://reactome.org/PathwayBrowser/#/R-SSC-9667952 ANKLE2 is deacetylated by SIRT2 IEA Sus scrofa 57540 R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 57540 R-SSC-9727349 https://reactome.org/PathwayBrowser/#/R-SSC-9727349 XDH dehydrogenates xanthine to form urate IEA Sus scrofa 57540 R-SSC-9748945 https://reactome.org/PathwayBrowser/#/R-SSC-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Sus scrofa 57540 R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 57540 R-SSC-9759549 https://reactome.org/PathwayBrowser/#/R-SSC-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Sus scrofa 57540 R-SSC-977348 https://reactome.org/PathwayBrowser/#/R-SSC-977348 PHGDH tetramer dehydrogenates 3PG IEA Sus scrofa 57540 R-SSC-9853499 https://reactome.org/PathwayBrowser/#/R-SSC-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 57540 R-SSC-9854463 https://reactome.org/PathwayBrowser/#/R-SSC-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Sus scrofa 57540 R-SSC-9856871 https://reactome.org/PathwayBrowser/#/R-SSC-9856871 MDH1 reduces OA IEA Sus scrofa 57540 R-SSC-9861616 https://reactome.org/PathwayBrowser/#/R-SSC-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 57540 R-SSC-9861626 https://reactome.org/PathwayBrowser/#/R-SSC-9861626 SIRT4 cleaves lipoyl from DLAT IEA Sus scrofa 57540 R-XTR-109343 https://reactome.org/PathwayBrowser/#/R-XTR-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Xenopus tropicalis 57540 R-XTR-1614362 https://reactome.org/PathwayBrowser/#/R-XTR-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Xenopus tropicalis 57540 R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Xenopus tropicalis 57540 R-XTR-173597 https://reactome.org/PathwayBrowser/#/R-XTR-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Xenopus tropicalis 57540 R-XTR-174401 https://reactome.org/PathwayBrowser/#/R-XTR-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Xenopus tropicalis 57540 R-XTR-1855178 https://reactome.org/PathwayBrowser/#/R-XTR-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Xenopus tropicalis 57540 R-XTR-192097 https://reactome.org/PathwayBrowser/#/R-XTR-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Xenopus tropicalis 57540 R-XTR-193789 https://reactome.org/PathwayBrowser/#/R-XTR-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 57540 R-XTR-193816 https://reactome.org/PathwayBrowser/#/R-XTR-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Xenopus tropicalis 57540 R-XTR-197198 https://reactome.org/PathwayBrowser/#/R-XTR-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 57540 R-XTR-198824 https://reactome.org/PathwayBrowser/#/R-XTR-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Xenopus tropicalis 57540 R-XTR-2046089 https://reactome.org/PathwayBrowser/#/R-XTR-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Xenopus tropicalis 57540 R-XTR-2046092 https://reactome.org/PathwayBrowser/#/R-XTR-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Xenopus tropicalis 57540 R-XTR-204617 https://reactome.org/PathwayBrowser/#/R-XTR-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Xenopus tropicalis 57540 R-XTR-204647 https://reactome.org/PathwayBrowser/#/R-XTR-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Xenopus tropicalis 57540 R-XTR-204662 https://reactome.org/PathwayBrowser/#/R-XTR-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Xenopus tropicalis 57540 R-XTR-2161779 https://reactome.org/PathwayBrowser/#/R-XTR-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Xenopus tropicalis 57540 R-XTR-2162078 https://reactome.org/PathwayBrowser/#/R-XTR-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Xenopus tropicalis 57540 R-XTR-2162194 https://reactome.org/PathwayBrowser/#/R-XTR-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Xenopus tropicalis 57540 R-XTR-2454081 https://reactome.org/PathwayBrowser/#/R-XTR-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Xenopus tropicalis 57540 R-XTR-380608 https://reactome.org/PathwayBrowser/#/R-XTR-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Xenopus tropicalis 57540 R-XTR-450971 https://reactome.org/PathwayBrowser/#/R-XTR-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Xenopus tropicalis 57540 R-XTR-508369 https://reactome.org/PathwayBrowser/#/R-XTR-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Xenopus tropicalis 57540 R-XTR-508473 https://reactome.org/PathwayBrowser/#/R-XTR-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Xenopus tropicalis 57540 R-XTR-5362518 https://reactome.org/PathwayBrowser/#/R-XTR-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Xenopus tropicalis 57540 R-XTR-5362522 https://reactome.org/PathwayBrowser/#/R-XTR-5362522 ALDHs oxidise atRAL to atRA IEA Xenopus tropicalis 57540 R-XTR-5362564 https://reactome.org/PathwayBrowser/#/R-XTR-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Xenopus tropicalis 57540 R-XTR-5362721 https://reactome.org/PathwayBrowser/#/R-XTR-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 57540 R-XTR-5651723 https://reactome.org/PathwayBrowser/#/R-XTR-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Xenopus tropicalis 57540 R-XTR-5652195 https://reactome.org/PathwayBrowser/#/R-XTR-5652195 SORD oxidizes D-sorbitol to Fru IEA Xenopus tropicalis 57540 R-XTR-5661290 https://reactome.org/PathwayBrowser/#/R-XTR-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Xenopus tropicalis 57540 R-XTR-5662471 https://reactome.org/PathwayBrowser/#/R-XTR-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Xenopus tropicalis 57540 R-XTR-5685953 https://reactome.org/PathwayBrowser/#/R-XTR-5685953 SIRT6 deacetylates RBBP8 IEA Xenopus tropicalis 57540 R-XTR-5688276 https://reactome.org/PathwayBrowser/#/R-XTR-5688276 SIRT4 transfers ADPRib to GLUD IEA Xenopus tropicalis 57540 R-XTR-5688294 https://reactome.org/PathwayBrowser/#/R-XTR-5688294 SIRT5 deacetylates Cytochrome C IEA Xenopus tropicalis 57540 R-XTR-5692237 https://reactome.org/PathwayBrowser/#/R-XTR-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Xenopus tropicalis 57540 R-XTR-5694018 https://reactome.org/PathwayBrowser/#/R-XTR-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Xenopus tropicalis 57540 R-XTR-5696080 https://reactome.org/PathwayBrowser/#/R-XTR-5696080 ALDH3B1 oxidises HXAL to PALM IEA Xenopus tropicalis 57540 R-XTR-5696091 https://reactome.org/PathwayBrowser/#/R-XTR-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Xenopus tropicalis 57540 R-XTR-5696101 https://reactome.org/PathwayBrowser/#/R-XTR-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Xenopus tropicalis 57540 R-XTR-5696655 https://reactome.org/PathwayBrowser/#/R-XTR-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Xenopus tropicalis 57540 R-XTR-6783939 https://reactome.org/PathwayBrowser/#/R-XTR-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 57540 R-XTR-6784399 https://reactome.org/PathwayBrowser/#/R-XTR-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Xenopus tropicalis 57540 R-XTR-6797955 https://reactome.org/PathwayBrowser/#/R-XTR-6797955 ALDH7A1 oxidises BETALD to BET IEA Xenopus tropicalis 57540 R-XTR-6801328 https://reactome.org/PathwayBrowser/#/R-XTR-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Xenopus tropicalis 57540 R-XTR-6806831 https://reactome.org/PathwayBrowser/#/R-XTR-6806831 CYB5Rs reduce MetHb to HbA IEA Xenopus tropicalis 57540 R-XTR-6807826 https://reactome.org/PathwayBrowser/#/R-XTR-6807826 LDHAL6B reduces PYR to LACT IEA Xenopus tropicalis 57540 R-XTR-6808464 https://reactome.org/PathwayBrowser/#/R-XTR-6808464 ALDH3B2 oxidises HXAL to PALM IEA Xenopus tropicalis 57540 R-XTR-6809264 https://reactome.org/PathwayBrowser/#/R-XTR-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Xenopus tropicalis 57540 R-XTR-6813749 https://reactome.org/PathwayBrowser/#/R-XTR-6813749 ALDH1A1 oxidises GA to DGA IEA Xenopus tropicalis 57540 R-XTR-70369 https://reactome.org/PathwayBrowser/#/R-XTR-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Xenopus tropicalis 57540 R-XTR-70449 https://reactome.org/PathwayBrowser/#/R-XTR-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Xenopus tropicalis 57540 R-XTR-70482 https://reactome.org/PathwayBrowser/#/R-XTR-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Xenopus tropicalis 57540 R-XTR-70510 https://reactome.org/PathwayBrowser/#/R-XTR-70510 LDH tetramer oxidises LACT to PYR IEA Xenopus tropicalis 57540 R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Xenopus tropicalis 57540 R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Xenopus tropicalis 57540 R-XTR-70664 https://reactome.org/PathwayBrowser/#/R-XTR-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 57540 R-XTR-70679 https://reactome.org/PathwayBrowser/#/R-XTR-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Xenopus tropicalis 57540 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 57540 R-XTR-70837 https://reactome.org/PathwayBrowser/#/R-XTR-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Xenopus tropicalis 57540 R-XTR-70885 https://reactome.org/PathwayBrowser/#/R-XTR-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Xenopus tropicalis 57540 R-XTR-70893 https://reactome.org/PathwayBrowser/#/R-XTR-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 57540 R-XTR-70903 https://reactome.org/PathwayBrowser/#/R-XTR-70903 urocanate + H2O => 4-imidazolone-5-propionate IEA Xenopus tropicalis 57540 R-XTR-70940 https://reactome.org/PathwayBrowser/#/R-XTR-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Xenopus tropicalis 57540 R-XTR-70941 https://reactome.org/PathwayBrowser/#/R-XTR-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Xenopus tropicalis 57540 R-XTR-70979 https://reactome.org/PathwayBrowser/#/R-XTR-70979 MDH2 dimer dehydrogenates MAL IEA Xenopus tropicalis 57540 R-XTR-71037 https://reactome.org/PathwayBrowser/#/R-XTR-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 57540 R-XTR-71130 https://reactome.org/PathwayBrowser/#/R-XTR-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Xenopus tropicalis 57540 R-XTR-71260 https://reactome.org/PathwayBrowser/#/R-XTR-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Xenopus tropicalis 57540 R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 57540 R-XTR-71707 https://reactome.org/PathwayBrowser/#/R-XTR-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Xenopus tropicalis 57540 R-XTR-71723 https://reactome.org/PathwayBrowser/#/R-XTR-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Xenopus tropicalis 57540 R-XTR-71849 https://reactome.org/PathwayBrowser/#/R-XTR-71849 LDH tetramer reduces PYR to LACT IEA Xenopus tropicalis 57540 R-XTR-73794 https://reactome.org/PathwayBrowser/#/R-XTR-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Xenopus tropicalis 57540 R-XTR-73912 https://reactome.org/PathwayBrowser/#/R-XTR-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Xenopus tropicalis 57540 R-XTR-73920 https://reactome.org/PathwayBrowser/#/R-XTR-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Xenopus tropicalis 57540 R-XTR-75889 https://reactome.org/PathwayBrowser/#/R-XTR-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Xenopus tropicalis 57540 R-XTR-77254 https://reactome.org/PathwayBrowser/#/R-XTR-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Xenopus tropicalis 57540 R-XTR-77283 https://reactome.org/PathwayBrowser/#/R-XTR-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Xenopus tropicalis 57540 R-XTR-77303 https://reactome.org/PathwayBrowser/#/R-XTR-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Xenopus tropicalis 57540 R-XTR-77312 https://reactome.org/PathwayBrowser/#/R-XTR-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Xenopus tropicalis 57540 R-XTR-77323 https://reactome.org/PathwayBrowser/#/R-XTR-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Xenopus tropicalis 57540 R-XTR-77331 https://reactome.org/PathwayBrowser/#/R-XTR-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Xenopus tropicalis 57540 R-XTR-77342 https://reactome.org/PathwayBrowser/#/R-XTR-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Xenopus tropicalis 57540 R-XTR-8870346 https://reactome.org/PathwayBrowser/#/R-XTR-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Xenopus tropicalis 57540 R-XTR-888548 https://reactome.org/PathwayBrowser/#/R-XTR-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Xenopus tropicalis 57540 R-XTR-8936442 https://reactome.org/PathwayBrowser/#/R-XTR-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Xenopus tropicalis 57540 R-XTR-8938073 https://reactome.org/PathwayBrowser/#/R-XTR-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) IEA Xenopus tropicalis 57540 R-XTR-8938076 https://reactome.org/PathwayBrowser/#/R-XTR-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Xenopus tropicalis 57540 R-XTR-8940070 https://reactome.org/PathwayBrowser/#/R-XTR-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Xenopus tropicalis 57540 R-XTR-8955030 https://reactome.org/PathwayBrowser/#/R-XTR-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 57540 R-XTR-8956458 https://reactome.org/PathwayBrowser/#/R-XTR-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Xenopus tropicalis 57540 R-XTR-9012268 https://reactome.org/PathwayBrowser/#/R-XTR-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 57540 R-XTR-9023968 https://reactome.org/PathwayBrowser/#/R-XTR-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Xenopus tropicalis 57540 R-XTR-9024766 https://reactome.org/PathwayBrowser/#/R-XTR-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Xenopus tropicalis 57540 R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 57540 R-XTR-9727349 https://reactome.org/PathwayBrowser/#/R-XTR-9727349 XDH dehydrogenates xanthine to form urate IEA Xenopus tropicalis 57540 R-XTR-9748945 https://reactome.org/PathwayBrowser/#/R-XTR-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Xenopus tropicalis 57540 R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 57540 R-XTR-9759549 https://reactome.org/PathwayBrowser/#/R-XTR-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Xenopus tropicalis 57540 R-XTR-977348 https://reactome.org/PathwayBrowser/#/R-XTR-977348 PHGDH tetramer dehydrogenates 3PG IEA Xenopus tropicalis 57540 R-XTR-9853499 https://reactome.org/PathwayBrowser/#/R-XTR-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 57540 R-XTR-9856871 https://reactome.org/PathwayBrowser/#/R-XTR-9856871 MDH1 reduces OA IEA Xenopus tropicalis 57540 R-XTR-9861616 https://reactome.org/PathwayBrowser/#/R-XTR-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 57540 R-XTR-9861626 https://reactome.org/PathwayBrowser/#/R-XTR-9861626 SIRT4 cleaves lipoyl from DLAT IEA Xenopus tropicalis 57560 R-BTA-1482604 https://reactome.org/PathwayBrowser/#/R-BTA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Bos taurus 57560 R-BTA-1482612 https://reactome.org/PathwayBrowser/#/R-BTA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 57560 R-BTA-1482656 https://reactome.org/PathwayBrowser/#/R-BTA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Bos taurus 57560 R-BTA-1482679 https://reactome.org/PathwayBrowser/#/R-BTA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Bos taurus 57560 R-BTA-1482685 https://reactome.org/PathwayBrowser/#/R-BTA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 57560 R-BTA-1482745 https://reactome.org/PathwayBrowser/#/R-BTA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Bos taurus 57560 R-BTA-1482759 https://reactome.org/PathwayBrowser/#/R-BTA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Bos taurus 57560 R-BTA-1482771 https://reactome.org/PathwayBrowser/#/R-BTA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Bos taurus 57560 R-BTA-1482776 https://reactome.org/PathwayBrowser/#/R-BTA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Bos taurus 57560 R-BTA-1482777 https://reactome.org/PathwayBrowser/#/R-BTA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Bos taurus 57560 R-BTA-1482811 https://reactome.org/PathwayBrowser/#/R-BTA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Bos taurus 57560 R-BTA-1482816 https://reactome.org/PathwayBrowser/#/R-BTA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Bos taurus 57560 R-BTA-1482825 https://reactome.org/PathwayBrowser/#/R-BTA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Bos taurus 57560 R-BTA-1482828 https://reactome.org/PathwayBrowser/#/R-BTA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Bos taurus 57560 R-BTA-1482847 https://reactome.org/PathwayBrowser/#/R-BTA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Bos taurus 57560 R-BTA-1482856 https://reactome.org/PathwayBrowser/#/R-BTA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Bos taurus 57560 R-BTA-1482862 https://reactome.org/PathwayBrowser/#/R-BTA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Bos taurus 57560 R-BTA-1482868 https://reactome.org/PathwayBrowser/#/R-BTA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Bos taurus 57560 R-BTA-1482884 https://reactome.org/PathwayBrowser/#/R-BTA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Bos taurus 57560 R-BTA-1482887 https://reactome.org/PathwayBrowser/#/R-BTA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Bos taurus 57560 R-BTA-1482897 https://reactome.org/PathwayBrowser/#/R-BTA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Bos taurus 57560 R-BTA-1482900 https://reactome.org/PathwayBrowser/#/R-BTA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Bos taurus 57560 R-BTA-1482907 https://reactome.org/PathwayBrowser/#/R-BTA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Bos taurus 57560 R-BTA-1482920 https://reactome.org/PathwayBrowser/#/R-BTA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Bos taurus 57560 R-BTA-1482932 https://reactome.org/PathwayBrowser/#/R-BTA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Bos taurus 57560 R-BTA-1602368 https://reactome.org/PathwayBrowser/#/R-BTA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Bos taurus 57560 R-BTA-1602374 https://reactome.org/PathwayBrowser/#/R-BTA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Bos taurus 57560 R-BTA-1602377 https://reactome.org/PathwayBrowser/#/R-BTA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Bos taurus 57560 R-BTA-1602398 https://reactome.org/PathwayBrowser/#/R-BTA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Bos taurus 57560 R-BTA-1602399 https://reactome.org/PathwayBrowser/#/R-BTA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Bos taurus 57560 R-BTA-1602417 https://reactome.org/PathwayBrowser/#/R-BTA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Bos taurus 57560 R-BTA-1602446 https://reactome.org/PathwayBrowser/#/R-BTA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Bos taurus 57560 R-BTA-162729 https://reactome.org/PathwayBrowser/#/R-BTA-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Bos taurus 57560 R-BTA-5334794 https://reactome.org/PathwayBrowser/#/R-BTA-5334794 FABPs bind LCFAs IEA Bos taurus 57560 R-BTA-6786650 https://reactome.org/PathwayBrowser/#/R-BTA-6786650 DDHD1,2 hydrolyse PA IEA Bos taurus 57560 R-BTA-6792445 https://reactome.org/PathwayBrowser/#/R-BTA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Bos taurus 57560 R-BTA-6813720 https://reactome.org/PathwayBrowser/#/R-BTA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Bos taurus 57560 R-BTA-6814254 https://reactome.org/PathwayBrowser/#/R-BTA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Bos taurus 57560 R-BTA-8848338 https://reactome.org/PathwayBrowser/#/R-BTA-8848338 PNPLA4 hydrolyzes TAG IEA Bos taurus 57560 R-BTA-8937442 https://reactome.org/PathwayBrowser/#/R-BTA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Bos taurus 57560 R-BTA-8952251 https://reactome.org/PathwayBrowser/#/R-BTA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Bos taurus 57560 R-CEL-1482604 https://reactome.org/PathwayBrowser/#/R-CEL-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Caenorhabditis elegans 57560 R-CEL-1482656 https://reactome.org/PathwayBrowser/#/R-CEL-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Caenorhabditis elegans 57560 R-CEL-1482679 https://reactome.org/PathwayBrowser/#/R-CEL-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Caenorhabditis elegans 57560 R-CEL-1482776 https://reactome.org/PathwayBrowser/#/R-CEL-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Caenorhabditis elegans 57560 R-CEL-1482777 https://reactome.org/PathwayBrowser/#/R-CEL-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Caenorhabditis elegans 57560 R-CEL-1482811 https://reactome.org/PathwayBrowser/#/R-CEL-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Caenorhabditis elegans 57560 R-CEL-1482816 https://reactome.org/PathwayBrowser/#/R-CEL-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Caenorhabditis elegans 57560 R-CEL-1482856 https://reactome.org/PathwayBrowser/#/R-CEL-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Caenorhabditis elegans 57560 R-CEL-1482868 https://reactome.org/PathwayBrowser/#/R-CEL-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Caenorhabditis elegans 57560 R-CEL-1482884 https://reactome.org/PathwayBrowser/#/R-CEL-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Caenorhabditis elegans 57560 R-CEL-1482887 https://reactome.org/PathwayBrowser/#/R-CEL-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Caenorhabditis elegans 57560 R-CEL-1482900 https://reactome.org/PathwayBrowser/#/R-CEL-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Caenorhabditis elegans 57560 R-CEL-1482907 https://reactome.org/PathwayBrowser/#/R-CEL-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Caenorhabditis elegans 57560 R-CEL-1602368 https://reactome.org/PathwayBrowser/#/R-CEL-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Caenorhabditis elegans 57560 R-CEL-1602374 https://reactome.org/PathwayBrowser/#/R-CEL-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Caenorhabditis elegans 57560 R-CEL-1602377 https://reactome.org/PathwayBrowser/#/R-CEL-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Caenorhabditis elegans 57560 R-CEL-1602398 https://reactome.org/PathwayBrowser/#/R-CEL-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Caenorhabditis elegans 57560 R-CEL-1602399 https://reactome.org/PathwayBrowser/#/R-CEL-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Caenorhabditis elegans 57560 R-CEL-1602417 https://reactome.org/PathwayBrowser/#/R-CEL-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Caenorhabditis elegans 57560 R-CEL-1602446 https://reactome.org/PathwayBrowser/#/R-CEL-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Caenorhabditis elegans 57560 R-CEL-5334794 https://reactome.org/PathwayBrowser/#/R-CEL-5334794 FABPs bind LCFAs IEA Caenorhabditis elegans 57560 R-CEL-6813720 https://reactome.org/PathwayBrowser/#/R-CEL-6813720 NCEH1 hydrolyzes cholesterol esters IEA Caenorhabditis elegans 57560 R-CEL-6814254 https://reactome.org/PathwayBrowser/#/R-CEL-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Caenorhabditis elegans 57560 R-CEL-8848339 https://reactome.org/PathwayBrowser/#/R-CEL-8848339 PNPLA5 hydrolyzes TAG IEA Caenorhabditis elegans 57560 R-CEL-8937442 https://reactome.org/PathwayBrowser/#/R-CEL-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Caenorhabditis elegans 57560 R-CEL-8952251 https://reactome.org/PathwayBrowser/#/R-CEL-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Caenorhabditis elegans 57560 R-CFA-1482604 https://reactome.org/PathwayBrowser/#/R-CFA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Canis familiaris 57560 R-CFA-1482612 https://reactome.org/PathwayBrowser/#/R-CFA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 57560 R-CFA-1482656 https://reactome.org/PathwayBrowser/#/R-CFA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Canis familiaris 57560 R-CFA-1482685 https://reactome.org/PathwayBrowser/#/R-CFA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 57560 R-CFA-1482745 https://reactome.org/PathwayBrowser/#/R-CFA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Canis familiaris 57560 R-CFA-1482759 https://reactome.org/PathwayBrowser/#/R-CFA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Canis familiaris 57560 R-CFA-1482771 https://reactome.org/PathwayBrowser/#/R-CFA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Canis familiaris 57560 R-CFA-1482777 https://reactome.org/PathwayBrowser/#/R-CFA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Canis familiaris 57560 R-CFA-1482811 https://reactome.org/PathwayBrowser/#/R-CFA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Canis familiaris 57560 R-CFA-1482816 https://reactome.org/PathwayBrowser/#/R-CFA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Canis familiaris 57560 R-CFA-1482825 https://reactome.org/PathwayBrowser/#/R-CFA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Canis familiaris 57560 R-CFA-1482828 https://reactome.org/PathwayBrowser/#/R-CFA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Canis familiaris 57560 R-CFA-1482847 https://reactome.org/PathwayBrowser/#/R-CFA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Canis familiaris 57560 R-CFA-1482856 https://reactome.org/PathwayBrowser/#/R-CFA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Canis familiaris 57560 R-CFA-1482862 https://reactome.org/PathwayBrowser/#/R-CFA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Canis familiaris 57560 R-CFA-1482884 https://reactome.org/PathwayBrowser/#/R-CFA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Canis familiaris 57560 R-CFA-1482887 https://reactome.org/PathwayBrowser/#/R-CFA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Canis familiaris 57560 R-CFA-1482897 https://reactome.org/PathwayBrowser/#/R-CFA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Canis familiaris 57560 R-CFA-1482900 https://reactome.org/PathwayBrowser/#/R-CFA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Canis familiaris 57560 R-CFA-1482920 https://reactome.org/PathwayBrowser/#/R-CFA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Canis familiaris 57560 R-CFA-1482932 https://reactome.org/PathwayBrowser/#/R-CFA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Canis familiaris 57560 R-CFA-1602368 https://reactome.org/PathwayBrowser/#/R-CFA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Canis familiaris 57560 R-CFA-1602374 https://reactome.org/PathwayBrowser/#/R-CFA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Canis familiaris 57560 R-CFA-1602377 https://reactome.org/PathwayBrowser/#/R-CFA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Canis familiaris 57560 R-CFA-1602398 https://reactome.org/PathwayBrowser/#/R-CFA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Canis familiaris 57560 R-CFA-1602399 https://reactome.org/PathwayBrowser/#/R-CFA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Canis familiaris 57560 R-CFA-1602417 https://reactome.org/PathwayBrowser/#/R-CFA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Canis familiaris 57560 R-CFA-1602446 https://reactome.org/PathwayBrowser/#/R-CFA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Canis familiaris 57560 R-CFA-162729 https://reactome.org/PathwayBrowser/#/R-CFA-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Canis familiaris 57560 R-CFA-5334794 https://reactome.org/PathwayBrowser/#/R-CFA-5334794 FABPs bind LCFAs IEA Canis familiaris 57560 R-CFA-6786650 https://reactome.org/PathwayBrowser/#/R-CFA-6786650 DDHD1,2 hydrolyse PA IEA Canis familiaris 57560 R-CFA-6792445 https://reactome.org/PathwayBrowser/#/R-CFA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Canis familiaris 57560 R-CFA-6813720 https://reactome.org/PathwayBrowser/#/R-CFA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Canis familiaris 57560 R-CFA-6814254 https://reactome.org/PathwayBrowser/#/R-CFA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Canis familiaris 57560 R-CFA-8848338 https://reactome.org/PathwayBrowser/#/R-CFA-8848338 PNPLA4 hydrolyzes TAG IEA Canis familiaris 57560 R-CFA-8848339 https://reactome.org/PathwayBrowser/#/R-CFA-8848339 PNPLA5 hydrolyzes TAG IEA Canis familiaris 57560 R-CFA-8869425 https://reactome.org/PathwayBrowser/#/R-CFA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Canis familiaris 57560 R-CFA-8952251 https://reactome.org/PathwayBrowser/#/R-CFA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Canis familiaris 57560 R-DDI-1482612 https://reactome.org/PathwayBrowser/#/R-DDI-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Dictyostelium discoideum 57560 R-DDI-1482685 https://reactome.org/PathwayBrowser/#/R-DDI-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Dictyostelium discoideum 57560 R-DDI-1482816 https://reactome.org/PathwayBrowser/#/R-DDI-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Dictyostelium discoideum 57560 R-DDI-1482825 https://reactome.org/PathwayBrowser/#/R-DDI-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Dictyostelium discoideum 57560 R-DDI-1482856 https://reactome.org/PathwayBrowser/#/R-DDI-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Dictyostelium discoideum 57560 R-DDI-1482884 https://reactome.org/PathwayBrowser/#/R-DDI-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Dictyostelium discoideum 57560 R-DDI-1482887 https://reactome.org/PathwayBrowser/#/R-DDI-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Dictyostelium discoideum 57560 R-DDI-6786650 https://reactome.org/PathwayBrowser/#/R-DDI-6786650 DDHD1,2 hydrolyse PA IEA Dictyostelium discoideum 57560 R-DDI-6813720 https://reactome.org/PathwayBrowser/#/R-DDI-6813720 NCEH1 hydrolyzes cholesterol esters IEA Dictyostelium discoideum 57560 R-DDI-8937442 https://reactome.org/PathwayBrowser/#/R-DDI-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Dictyostelium discoideum 57560 R-DME-1482604 https://reactome.org/PathwayBrowser/#/R-DME-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Drosophila melanogaster 57560 R-DME-1482656 https://reactome.org/PathwayBrowser/#/R-DME-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Drosophila melanogaster 57560 R-DME-1482679 https://reactome.org/PathwayBrowser/#/R-DME-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Drosophila melanogaster 57560 R-DME-1482776 https://reactome.org/PathwayBrowser/#/R-DME-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Drosophila melanogaster 57560 R-DME-1482777 https://reactome.org/PathwayBrowser/#/R-DME-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Drosophila melanogaster 57560 R-DME-1482811 https://reactome.org/PathwayBrowser/#/R-DME-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Drosophila melanogaster 57560 R-DME-1482816 https://reactome.org/PathwayBrowser/#/R-DME-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Drosophila melanogaster 57560 R-DME-1482856 https://reactome.org/PathwayBrowser/#/R-DME-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Drosophila melanogaster 57560 R-DME-1482868 https://reactome.org/PathwayBrowser/#/R-DME-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Drosophila melanogaster 57560 R-DME-1482884 https://reactome.org/PathwayBrowser/#/R-DME-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Drosophila melanogaster 57560 R-DME-1482887 https://reactome.org/PathwayBrowser/#/R-DME-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Drosophila melanogaster 57560 R-DME-1482900 https://reactome.org/PathwayBrowser/#/R-DME-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Drosophila melanogaster 57560 R-DME-1482907 https://reactome.org/PathwayBrowser/#/R-DME-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Drosophila melanogaster 57560 R-DME-1602368 https://reactome.org/PathwayBrowser/#/R-DME-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Drosophila melanogaster 57560 R-DME-1602374 https://reactome.org/PathwayBrowser/#/R-DME-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Drosophila melanogaster 57560 R-DME-1602377 https://reactome.org/PathwayBrowser/#/R-DME-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Drosophila melanogaster 57560 R-DME-1602398 https://reactome.org/PathwayBrowser/#/R-DME-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Drosophila melanogaster 57560 R-DME-1602399 https://reactome.org/PathwayBrowser/#/R-DME-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Drosophila melanogaster 57560 R-DME-1602417 https://reactome.org/PathwayBrowser/#/R-DME-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Drosophila melanogaster 57560 R-DME-1602446 https://reactome.org/PathwayBrowser/#/R-DME-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Drosophila melanogaster 57560 R-DME-5334794 https://reactome.org/PathwayBrowser/#/R-DME-5334794 FABPs bind LCFAs IEA Drosophila melanogaster 57560 R-DME-6792445 https://reactome.org/PathwayBrowser/#/R-DME-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Drosophila melanogaster 57560 R-DME-6814254 https://reactome.org/PathwayBrowser/#/R-DME-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Drosophila melanogaster 57560 R-DME-8848339 https://reactome.org/PathwayBrowser/#/R-DME-8848339 PNPLA5 hydrolyzes TAG IEA Drosophila melanogaster 57560 R-DME-8869425 https://reactome.org/PathwayBrowser/#/R-DME-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Drosophila melanogaster 57560 R-DME-8937442 https://reactome.org/PathwayBrowser/#/R-DME-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Drosophila melanogaster 57560 R-DME-8952251 https://reactome.org/PathwayBrowser/#/R-DME-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Drosophila melanogaster 57560 R-DRE-1482545 https://reactome.org/PathwayBrowser/#/R-DRE-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Danio rerio 57560 R-DRE-1482571 https://reactome.org/PathwayBrowser/#/R-DRE-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Danio rerio 57560 R-DRE-1482604 https://reactome.org/PathwayBrowser/#/R-DRE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Danio rerio 57560 R-DRE-1482612 https://reactome.org/PathwayBrowser/#/R-DRE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 57560 R-DRE-1482629 https://reactome.org/PathwayBrowser/#/R-DRE-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Danio rerio 57560 R-DRE-1482656 https://reactome.org/PathwayBrowser/#/R-DRE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Danio rerio 57560 R-DRE-1482685 https://reactome.org/PathwayBrowser/#/R-DRE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 57560 R-DRE-1482696 https://reactome.org/PathwayBrowser/#/R-DRE-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Danio rerio 57560 R-DRE-1482759 https://reactome.org/PathwayBrowser/#/R-DRE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Danio rerio 57560 R-DRE-1482771 https://reactome.org/PathwayBrowser/#/R-DRE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Danio rerio 57560 R-DRE-1482777 https://reactome.org/PathwayBrowser/#/R-DRE-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Danio rerio 57560 R-DRE-1482811 https://reactome.org/PathwayBrowser/#/R-DRE-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Danio rerio 57560 R-DRE-1482816 https://reactome.org/PathwayBrowser/#/R-DRE-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Danio rerio 57560 R-DRE-1482825 https://reactome.org/PathwayBrowser/#/R-DRE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Danio rerio 57560 R-DRE-1482827 https://reactome.org/PathwayBrowser/#/R-DRE-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Danio rerio 57560 R-DRE-1482828 https://reactome.org/PathwayBrowser/#/R-DRE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Danio rerio 57560 R-DRE-1482856 https://reactome.org/PathwayBrowser/#/R-DRE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Danio rerio 57560 R-DRE-1482862 https://reactome.org/PathwayBrowser/#/R-DRE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Danio rerio 57560 R-DRE-1482868 https://reactome.org/PathwayBrowser/#/R-DRE-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Danio rerio 57560 R-DRE-1482884 https://reactome.org/PathwayBrowser/#/R-DRE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Danio rerio 57560 R-DRE-1482892 https://reactome.org/PathwayBrowser/#/R-DRE-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Danio rerio 57560 R-DRE-1482897 https://reactome.org/PathwayBrowser/#/R-DRE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Danio rerio 57560 R-DRE-1482900 https://reactome.org/PathwayBrowser/#/R-DRE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Danio rerio 57560 R-DRE-1602368 https://reactome.org/PathwayBrowser/#/R-DRE-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Danio rerio 57560 R-DRE-1602374 https://reactome.org/PathwayBrowser/#/R-DRE-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Danio rerio 57560 R-DRE-1602377 https://reactome.org/PathwayBrowser/#/R-DRE-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Danio rerio 57560 R-DRE-1602398 https://reactome.org/PathwayBrowser/#/R-DRE-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Danio rerio 57560 R-DRE-1602417 https://reactome.org/PathwayBrowser/#/R-DRE-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Danio rerio 57560 R-DRE-1602446 https://reactome.org/PathwayBrowser/#/R-DRE-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Danio rerio 57560 R-DRE-5334794 https://reactome.org/PathwayBrowser/#/R-DRE-5334794 FABPs bind LCFAs IEA Danio rerio 57560 R-DRE-6792445 https://reactome.org/PathwayBrowser/#/R-DRE-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Danio rerio 57560 R-DRE-6813720 https://reactome.org/PathwayBrowser/#/R-DRE-6813720 NCEH1 hydrolyzes cholesterol esters IEA Danio rerio 57560 R-DRE-8848339 https://reactome.org/PathwayBrowser/#/R-DRE-8848339 PNPLA5 hydrolyzes TAG IEA Danio rerio 57560 R-DRE-8869425 https://reactome.org/PathwayBrowser/#/R-DRE-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Danio rerio 57560 R-DRE-8937442 https://reactome.org/PathwayBrowser/#/R-DRE-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Danio rerio 57560 R-GGA-1482604 https://reactome.org/PathwayBrowser/#/R-GGA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Gallus gallus 57560 R-GGA-1482612 https://reactome.org/PathwayBrowser/#/R-GGA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 57560 R-GGA-1482656 https://reactome.org/PathwayBrowser/#/R-GGA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Gallus gallus 57560 R-GGA-1482679 https://reactome.org/PathwayBrowser/#/R-GGA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Gallus gallus 57560 R-GGA-1482685 https://reactome.org/PathwayBrowser/#/R-GGA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 57560 R-GGA-1482745 https://reactome.org/PathwayBrowser/#/R-GGA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Gallus gallus 57560 R-GGA-1482759 https://reactome.org/PathwayBrowser/#/R-GGA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Gallus gallus 57560 R-GGA-1482771 https://reactome.org/PathwayBrowser/#/R-GGA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Gallus gallus 57560 R-GGA-1482776 https://reactome.org/PathwayBrowser/#/R-GGA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Gallus gallus 57560 R-GGA-1482777 https://reactome.org/PathwayBrowser/#/R-GGA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Gallus gallus 57560 R-GGA-1482811 https://reactome.org/PathwayBrowser/#/R-GGA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Gallus gallus 57560 R-GGA-1482816 https://reactome.org/PathwayBrowser/#/R-GGA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Gallus gallus 57560 R-GGA-1482825 https://reactome.org/PathwayBrowser/#/R-GGA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Gallus gallus 57560 R-GGA-1482828 https://reactome.org/PathwayBrowser/#/R-GGA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Gallus gallus 57560 R-GGA-1482847 https://reactome.org/PathwayBrowser/#/R-GGA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Gallus gallus 57560 R-GGA-1482856 https://reactome.org/PathwayBrowser/#/R-GGA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Gallus gallus 57560 R-GGA-1482862 https://reactome.org/PathwayBrowser/#/R-GGA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Gallus gallus 57560 R-GGA-1482868 https://reactome.org/PathwayBrowser/#/R-GGA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Gallus gallus 57560 R-GGA-1482884 https://reactome.org/PathwayBrowser/#/R-GGA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Gallus gallus 57560 R-GGA-1482887 https://reactome.org/PathwayBrowser/#/R-GGA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Gallus gallus 57560 R-GGA-1482897 https://reactome.org/PathwayBrowser/#/R-GGA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Gallus gallus 57560 R-GGA-1482900 https://reactome.org/PathwayBrowser/#/R-GGA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Gallus gallus 57560 R-GGA-1482907 https://reactome.org/PathwayBrowser/#/R-GGA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Gallus gallus 57560 R-GGA-1482920 https://reactome.org/PathwayBrowser/#/R-GGA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Gallus gallus 57560 R-GGA-1482932 https://reactome.org/PathwayBrowser/#/R-GGA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Gallus gallus 57560 R-GGA-1602368 https://reactome.org/PathwayBrowser/#/R-GGA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Gallus gallus 57560 R-GGA-1602374 https://reactome.org/PathwayBrowser/#/R-GGA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Gallus gallus 57560 R-GGA-1602377 https://reactome.org/PathwayBrowser/#/R-GGA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Gallus gallus 57560 R-GGA-1602398 https://reactome.org/PathwayBrowser/#/R-GGA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Gallus gallus 57560 R-GGA-1602399 https://reactome.org/PathwayBrowser/#/R-GGA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Gallus gallus 57560 R-GGA-1602417 https://reactome.org/PathwayBrowser/#/R-GGA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Gallus gallus 57560 R-GGA-1602446 https://reactome.org/PathwayBrowser/#/R-GGA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Gallus gallus 57560 R-GGA-5334794 https://reactome.org/PathwayBrowser/#/R-GGA-5334794 FABPs bind LCFAs IEA Gallus gallus 57560 R-GGA-6786650 https://reactome.org/PathwayBrowser/#/R-GGA-6786650 DDHD1,2 hydrolyse PA IEA Gallus gallus 57560 R-GGA-6792445 https://reactome.org/PathwayBrowser/#/R-GGA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Gallus gallus 57560 R-GGA-6813720 https://reactome.org/PathwayBrowser/#/R-GGA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Gallus gallus 57560 R-GGA-6814254 https://reactome.org/PathwayBrowser/#/R-GGA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Gallus gallus 57560 R-GGA-8848338 https://reactome.org/PathwayBrowser/#/R-GGA-8848338 PNPLA4 hydrolyzes TAG IEA Gallus gallus 57560 R-GGA-8848339 https://reactome.org/PathwayBrowser/#/R-GGA-8848339 PNPLA5 hydrolyzes TAG IEA Gallus gallus 57560 R-GGA-8869425 https://reactome.org/PathwayBrowser/#/R-GGA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Gallus gallus 57560 R-GGA-8937442 https://reactome.org/PathwayBrowser/#/R-GGA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Gallus gallus 57560 R-GGA-8952251 https://reactome.org/PathwayBrowser/#/R-GGA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Gallus gallus 57560 R-HSA-1482545 https://reactome.org/PathwayBrowser/#/R-HSA-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C TAS Homo sapiens 57560 R-HSA-1482571 https://reactome.org/PathwayBrowser/#/R-HSA-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C TAS Homo sapiens 57560 R-HSA-1482604 https://reactome.org/PathwayBrowser/#/R-HSA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) TAS Homo sapiens 57560 R-HSA-1482612 https://reactome.org/PathwayBrowser/#/R-HSA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 57560 R-HSA-1482629 https://reactome.org/PathwayBrowser/#/R-HSA-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C TAS Homo sapiens 57560 R-HSA-1482656 https://reactome.org/PathwayBrowser/#/R-HSA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] TAS Homo sapiens 57560 R-HSA-1482679 https://reactome.org/PathwayBrowser/#/R-HSA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A TAS Homo sapiens 57560 R-HSA-1482685 https://reactome.org/PathwayBrowser/#/R-HSA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 57560 R-HSA-1482696 https://reactome.org/PathwayBrowser/#/R-HSA-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C TAS Homo sapiens 57560 R-HSA-1482745 https://reactome.org/PathwayBrowser/#/R-HSA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) TAS Homo sapiens 57560 R-HSA-1482759 https://reactome.org/PathwayBrowser/#/R-HSA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) TAS Homo sapiens 57560 R-HSA-1482771 https://reactome.org/PathwayBrowser/#/R-HSA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] TAS Homo sapiens 57560 R-HSA-1482776 https://reactome.org/PathwayBrowser/#/R-HSA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A TAS Homo sapiens 57560 R-HSA-1482777 https://reactome.org/PathwayBrowser/#/R-HSA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 TAS Homo sapiens 57560 R-HSA-1482778 https://reactome.org/PathwayBrowser/#/R-HSA-1482778 CL is hydrolyzed to MLCL by PLA2G6 (IM) IEA Homo sapiens 57560 R-HSA-1482811 https://reactome.org/PathwayBrowser/#/R-HSA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 TAS Homo sapiens 57560 R-HSA-1482816 https://reactome.org/PathwayBrowser/#/R-HSA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] TAS Homo sapiens 57560 R-HSA-1482825 https://reactome.org/PathwayBrowser/#/R-HSA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] TAS Homo sapiens 57560 R-HSA-1482827 https://reactome.org/PathwayBrowser/#/R-HSA-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C TAS Homo sapiens 57560 R-HSA-1482828 https://reactome.org/PathwayBrowser/#/R-HSA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] TAS Homo sapiens 57560 R-HSA-1482847 https://reactome.org/PathwayBrowser/#/R-HSA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) TAS Homo sapiens 57560 R-HSA-1482856 https://reactome.org/PathwayBrowser/#/R-HSA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] TAS Homo sapiens 57560 R-HSA-1482862 https://reactome.org/PathwayBrowser/#/R-HSA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] TAS Homo sapiens 57560 R-HSA-1482868 https://reactome.org/PathwayBrowser/#/R-HSA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] TAS Homo sapiens 57560 R-HSA-1482884 https://reactome.org/PathwayBrowser/#/R-HSA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] TAS Homo sapiens 57560 R-HSA-1482887 https://reactome.org/PathwayBrowser/#/R-HSA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] TAS Homo sapiens 57560 R-HSA-1482892 https://reactome.org/PathwayBrowser/#/R-HSA-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C TAS Homo sapiens 57560 R-HSA-1482897 https://reactome.org/PathwayBrowser/#/R-HSA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] TAS Homo sapiens 57560 R-HSA-1482900 https://reactome.org/PathwayBrowser/#/R-HSA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] TAS Homo sapiens 57560 R-HSA-1482907 https://reactome.org/PathwayBrowser/#/R-HSA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A TAS Homo sapiens 57560 R-HSA-1482920 https://reactome.org/PathwayBrowser/#/R-HSA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] TAS Homo sapiens 57560 R-HSA-1482932 https://reactome.org/PathwayBrowser/#/R-HSA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] TAS Homo sapiens 57560 R-HSA-1602368 https://reactome.org/PathwayBrowser/#/R-HSA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] TAS Homo sapiens 57560 R-HSA-1602374 https://reactome.org/PathwayBrowser/#/R-HSA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] TAS Homo sapiens 57560 R-HSA-1602377 https://reactome.org/PathwayBrowser/#/R-HSA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] TAS Homo sapiens 57560 R-HSA-1602398 https://reactome.org/PathwayBrowser/#/R-HSA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] TAS Homo sapiens 57560 R-HSA-1602399 https://reactome.org/PathwayBrowser/#/R-HSA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 TAS Homo sapiens 57560 R-HSA-1602417 https://reactome.org/PathwayBrowser/#/R-HSA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] TAS Homo sapiens 57560 R-HSA-1602446 https://reactome.org/PathwayBrowser/#/R-HSA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] TAS Homo sapiens 57560 R-HSA-162729 https://reactome.org/PathwayBrowser/#/R-HSA-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid TAS Homo sapiens 57560 R-HSA-163402 https://reactome.org/PathwayBrowser/#/R-HSA-163402 diacylglycerol + H2O -> 2-acylglycerol + fatty acid IEA Homo sapiens 57560 R-HSA-163432 https://reactome.org/PathwayBrowser/#/R-HSA-163432 cholesterol ester + H2O -> cholesterol + fatty acid IEA Homo sapiens 57560 R-HSA-163551 https://reactome.org/PathwayBrowser/#/R-HSA-163551 triacylglycerol + H2O -> diacylglycerol + fatty acid IEA Homo sapiens 57560 R-HSA-163595 https://reactome.org/PathwayBrowser/#/R-HSA-163595 2-acylglycerol + H2O -> glycerol + fatty acid IEA Homo sapiens 57560 R-HSA-5334794 https://reactome.org/PathwayBrowser/#/R-HSA-5334794 FABPs bind LCFAs TAS Homo sapiens 57560 R-HSA-6786650 https://reactome.org/PathwayBrowser/#/R-HSA-6786650 DDHD1,2 hydrolyse PA TAS Homo sapiens 57560 R-HSA-6792445 https://reactome.org/PathwayBrowser/#/R-HSA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA TAS Homo sapiens 57560 R-HSA-6813720 https://reactome.org/PathwayBrowser/#/R-HSA-6813720 NCEH1 hydrolyzes cholesterol esters TAS Homo sapiens 57560 R-HSA-6814254 https://reactome.org/PathwayBrowser/#/R-HSA-6814254 PNPLA6 hydrolyzes LysoPtdCho TAS Homo sapiens 57560 R-HSA-6814766 https://reactome.org/PathwayBrowser/#/R-HSA-6814766 GDPD1 hydrolyzes LysoPtdCho IEA Homo sapiens 57560 R-HSA-6814778 https://reactome.org/PathwayBrowser/#/R-HSA-6814778 GDPD3 hydrolyzes LysoPtdCho IEA Homo sapiens 57560 R-HSA-8847912 https://reactome.org/PathwayBrowser/#/R-HSA-8847912 PNPLA7 hydrolyzes LysoPtdCho IEA Homo sapiens 57560 R-HSA-8848338 https://reactome.org/PathwayBrowser/#/R-HSA-8848338 PNPLA4 hydrolyzes TAG TAS Homo sapiens 57560 R-HSA-8848339 https://reactome.org/PathwayBrowser/#/R-HSA-8848339 PNPLA5 hydrolyzes TAG TAS Homo sapiens 57560 R-HSA-8869425 https://reactome.org/PathwayBrowser/#/R-HSA-8869425 PLA1A hydrolyses PS to 2-acyl LPS TAS Homo sapiens 57560 R-HSA-8937442 https://reactome.org/PathwayBrowser/#/R-HSA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) TAS Homo sapiens 57560 R-HSA-8952251 https://reactome.org/PathwayBrowser/#/R-HSA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) TAS Homo sapiens 57560 R-MMU-1482545 https://reactome.org/PathwayBrowser/#/R-MMU-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Mus musculus 57560 R-MMU-1482571 https://reactome.org/PathwayBrowser/#/R-MMU-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Mus musculus 57560 R-MMU-1482604 https://reactome.org/PathwayBrowser/#/R-MMU-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Mus musculus 57560 R-MMU-1482612 https://reactome.org/PathwayBrowser/#/R-MMU-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 57560 R-MMU-1482629 https://reactome.org/PathwayBrowser/#/R-MMU-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Mus musculus 57560 R-MMU-1482656 https://reactome.org/PathwayBrowser/#/R-MMU-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Mus musculus 57560 R-MMU-1482679 https://reactome.org/PathwayBrowser/#/R-MMU-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Mus musculus 57560 R-MMU-1482685 https://reactome.org/PathwayBrowser/#/R-MMU-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 57560 R-MMU-1482696 https://reactome.org/PathwayBrowser/#/R-MMU-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Mus musculus 57560 R-MMU-1482745 https://reactome.org/PathwayBrowser/#/R-MMU-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Mus musculus 57560 R-MMU-1482759 https://reactome.org/PathwayBrowser/#/R-MMU-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Mus musculus 57560 R-MMU-1482771 https://reactome.org/PathwayBrowser/#/R-MMU-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Mus musculus 57560 R-MMU-1482776 https://reactome.org/PathwayBrowser/#/R-MMU-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Mus musculus 57560 R-MMU-1482777 https://reactome.org/PathwayBrowser/#/R-MMU-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Mus musculus 57560 R-MMU-1482811 https://reactome.org/PathwayBrowser/#/R-MMU-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Mus musculus 57560 R-MMU-1482816 https://reactome.org/PathwayBrowser/#/R-MMU-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Mus musculus 57560 R-MMU-1482825 https://reactome.org/PathwayBrowser/#/R-MMU-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Mus musculus 57560 R-MMU-1482827 https://reactome.org/PathwayBrowser/#/R-MMU-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Mus musculus 57560 R-MMU-1482828 https://reactome.org/PathwayBrowser/#/R-MMU-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Mus musculus 57560 R-MMU-1482847 https://reactome.org/PathwayBrowser/#/R-MMU-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Mus musculus 57560 R-MMU-1482856 https://reactome.org/PathwayBrowser/#/R-MMU-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Mus musculus 57560 R-MMU-1482862 https://reactome.org/PathwayBrowser/#/R-MMU-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Mus musculus 57560 R-MMU-1482868 https://reactome.org/PathwayBrowser/#/R-MMU-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Mus musculus 57560 R-MMU-1482884 https://reactome.org/PathwayBrowser/#/R-MMU-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Mus musculus 57560 R-MMU-1482887 https://reactome.org/PathwayBrowser/#/R-MMU-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Mus musculus 57560 R-MMU-1482892 https://reactome.org/PathwayBrowser/#/R-MMU-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Mus musculus 57560 R-MMU-1482897 https://reactome.org/PathwayBrowser/#/R-MMU-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Mus musculus 57560 R-MMU-1482900 https://reactome.org/PathwayBrowser/#/R-MMU-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Mus musculus 57560 R-MMU-1482907 https://reactome.org/PathwayBrowser/#/R-MMU-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Mus musculus 57560 R-MMU-1482920 https://reactome.org/PathwayBrowser/#/R-MMU-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Mus musculus 57560 R-MMU-1482932 https://reactome.org/PathwayBrowser/#/R-MMU-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Mus musculus 57560 R-MMU-1602368 https://reactome.org/PathwayBrowser/#/R-MMU-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Mus musculus 57560 R-MMU-1602374 https://reactome.org/PathwayBrowser/#/R-MMU-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Mus musculus 57560 R-MMU-1602377 https://reactome.org/PathwayBrowser/#/R-MMU-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Mus musculus 57560 R-MMU-1602398 https://reactome.org/PathwayBrowser/#/R-MMU-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Mus musculus 57560 R-MMU-1602399 https://reactome.org/PathwayBrowser/#/R-MMU-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Mus musculus 57560 R-MMU-1602417 https://reactome.org/PathwayBrowser/#/R-MMU-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Mus musculus 57560 R-MMU-1602446 https://reactome.org/PathwayBrowser/#/R-MMU-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Mus musculus 57560 R-MMU-162729 https://reactome.org/PathwayBrowser/#/R-MMU-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Mus musculus 57560 R-MMU-5334794 https://reactome.org/PathwayBrowser/#/R-MMU-5334794 FABPs bind LCFAs IEA Mus musculus 57560 R-MMU-6786650 https://reactome.org/PathwayBrowser/#/R-MMU-6786650 DDHD1,2 hydrolyse PA IEA Mus musculus 57560 R-MMU-6792445 https://reactome.org/PathwayBrowser/#/R-MMU-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Mus musculus 57560 R-MMU-6813720 https://reactome.org/PathwayBrowser/#/R-MMU-6813720 NCEH1 hydrolyzes cholesterol esters IEA Mus musculus 57560 R-MMU-6814254 https://reactome.org/PathwayBrowser/#/R-MMU-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Mus musculus 57560 R-MMU-8847424 https://reactome.org/PathwayBrowser/#/R-MMU-8847424 Gdpd1 hydrolyzes LysoPtdCho TAS Mus musculus 57560 R-MMU-8847427 https://reactome.org/PathwayBrowser/#/R-MMU-8847427 Gdpd3 hydrolyzes LysoPtdCho TAS Mus musculus 57560 R-MMU-8847904 https://reactome.org/PathwayBrowser/#/R-MMU-8847904 Pnpla7 hydrolyzes LysoPtdCho TAS Mus musculus 57560 R-MMU-8848339 https://reactome.org/PathwayBrowser/#/R-MMU-8848339 PNPLA5 hydrolyzes TAG IEA Mus musculus 57560 R-MMU-8869425 https://reactome.org/PathwayBrowser/#/R-MMU-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Mus musculus 57560 R-MMU-8937442 https://reactome.org/PathwayBrowser/#/R-MMU-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Mus musculus 57560 R-MMU-8952251 https://reactome.org/PathwayBrowser/#/R-MMU-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Mus musculus 57560 R-PFA-1482777 https://reactome.org/PathwayBrowser/#/R-PFA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Plasmodium falciparum 57560 R-PFA-1482811 https://reactome.org/PathwayBrowser/#/R-PFA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Plasmodium falciparum 57560 R-PFA-6786650 https://reactome.org/PathwayBrowser/#/R-PFA-6786650 DDHD1,2 hydrolyse PA IEA Plasmodium falciparum 57560 R-PFA-8848338 https://reactome.org/PathwayBrowser/#/R-PFA-8848338 PNPLA4 hydrolyzes TAG IEA Plasmodium falciparum 57560 R-PFA-8848339 https://reactome.org/PathwayBrowser/#/R-PFA-8848339 PNPLA5 hydrolyzes TAG IEA Plasmodium falciparum 57560 R-RNO-1482545 https://reactome.org/PathwayBrowser/#/R-RNO-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Rattus norvegicus 57560 R-RNO-1482571 https://reactome.org/PathwayBrowser/#/R-RNO-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Rattus norvegicus 57560 R-RNO-1482604 https://reactome.org/PathwayBrowser/#/R-RNO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Rattus norvegicus 57560 R-RNO-1482612 https://reactome.org/PathwayBrowser/#/R-RNO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 57560 R-RNO-1482629 https://reactome.org/PathwayBrowser/#/R-RNO-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Rattus norvegicus 57560 R-RNO-1482656 https://reactome.org/PathwayBrowser/#/R-RNO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Rattus norvegicus 57560 R-RNO-1482679 https://reactome.org/PathwayBrowser/#/R-RNO-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Rattus norvegicus 57560 R-RNO-1482685 https://reactome.org/PathwayBrowser/#/R-RNO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 57560 R-RNO-1482696 https://reactome.org/PathwayBrowser/#/R-RNO-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Rattus norvegicus 57560 R-RNO-1482745 https://reactome.org/PathwayBrowser/#/R-RNO-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Rattus norvegicus 57560 R-RNO-1482759 https://reactome.org/PathwayBrowser/#/R-RNO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Rattus norvegicus 57560 R-RNO-1482771 https://reactome.org/PathwayBrowser/#/R-RNO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Rattus norvegicus 57560 R-RNO-1482776 https://reactome.org/PathwayBrowser/#/R-RNO-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Rattus norvegicus 57560 R-RNO-1482777 https://reactome.org/PathwayBrowser/#/R-RNO-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Rattus norvegicus 57560 R-RNO-1482811 https://reactome.org/PathwayBrowser/#/R-RNO-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Rattus norvegicus 57560 R-RNO-1482816 https://reactome.org/PathwayBrowser/#/R-RNO-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Rattus norvegicus 57560 R-RNO-1482825 https://reactome.org/PathwayBrowser/#/R-RNO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Rattus norvegicus 57560 R-RNO-1482827 https://reactome.org/PathwayBrowser/#/R-RNO-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Rattus norvegicus 57560 R-RNO-1482828 https://reactome.org/PathwayBrowser/#/R-RNO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Rattus norvegicus 57560 R-RNO-1482836 https://reactome.org/PathwayBrowser/#/R-RNO-1482836 CL is hydrolyzed to MLCL by Pla2g6 (IM) TAS Rattus norvegicus 57560 R-RNO-1482847 https://reactome.org/PathwayBrowser/#/R-RNO-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Rattus norvegicus 57560 R-RNO-1482856 https://reactome.org/PathwayBrowser/#/R-RNO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Rattus norvegicus 57560 R-RNO-1482862 https://reactome.org/PathwayBrowser/#/R-RNO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Rattus norvegicus 57560 R-RNO-1482868 https://reactome.org/PathwayBrowser/#/R-RNO-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Rattus norvegicus 57560 R-RNO-1482884 https://reactome.org/PathwayBrowser/#/R-RNO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Rattus norvegicus 57560 R-RNO-1482887 https://reactome.org/PathwayBrowser/#/R-RNO-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Rattus norvegicus 57560 R-RNO-1482892 https://reactome.org/PathwayBrowser/#/R-RNO-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Rattus norvegicus 57560 R-RNO-1482897 https://reactome.org/PathwayBrowser/#/R-RNO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Rattus norvegicus 57560 R-RNO-1482900 https://reactome.org/PathwayBrowser/#/R-RNO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Rattus norvegicus 57560 R-RNO-1482907 https://reactome.org/PathwayBrowser/#/R-RNO-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Rattus norvegicus 57560 R-RNO-1482920 https://reactome.org/PathwayBrowser/#/R-RNO-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Rattus norvegicus 57560 R-RNO-1482932 https://reactome.org/PathwayBrowser/#/R-RNO-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Rattus norvegicus 57560 R-RNO-1602368 https://reactome.org/PathwayBrowser/#/R-RNO-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Rattus norvegicus 57560 R-RNO-1602374 https://reactome.org/PathwayBrowser/#/R-RNO-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Rattus norvegicus 57560 R-RNO-1602377 https://reactome.org/PathwayBrowser/#/R-RNO-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Rattus norvegicus 57560 R-RNO-1602398 https://reactome.org/PathwayBrowser/#/R-RNO-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Rattus norvegicus 57560 R-RNO-1602399 https://reactome.org/PathwayBrowser/#/R-RNO-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Rattus norvegicus 57560 R-RNO-1602417 https://reactome.org/PathwayBrowser/#/R-RNO-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Rattus norvegicus 57560 R-RNO-1602446 https://reactome.org/PathwayBrowser/#/R-RNO-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Rattus norvegicus 57560 R-RNO-162729 https://reactome.org/PathwayBrowser/#/R-RNO-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Rattus norvegicus 57560 R-RNO-5334794 https://reactome.org/PathwayBrowser/#/R-RNO-5334794 FABPs bind LCFAs IEA Rattus norvegicus 57560 R-RNO-6786650 https://reactome.org/PathwayBrowser/#/R-RNO-6786650 DDHD1,2 hydrolyse PA IEA Rattus norvegicus 57560 R-RNO-6792445 https://reactome.org/PathwayBrowser/#/R-RNO-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Rattus norvegicus 57560 R-RNO-6813720 https://reactome.org/PathwayBrowser/#/R-RNO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Rattus norvegicus 57560 R-RNO-6814254 https://reactome.org/PathwayBrowser/#/R-RNO-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Rattus norvegicus 57560 R-RNO-8848338 https://reactome.org/PathwayBrowser/#/R-RNO-8848338 PNPLA4 hydrolyzes TAG IEA Rattus norvegicus 57560 R-RNO-8848339 https://reactome.org/PathwayBrowser/#/R-RNO-8848339 PNPLA5 hydrolyzes TAG IEA Rattus norvegicus 57560 R-RNO-8869425 https://reactome.org/PathwayBrowser/#/R-RNO-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Rattus norvegicus 57560 R-RNO-8952251 https://reactome.org/PathwayBrowser/#/R-RNO-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Rattus norvegicus 57560 R-SCE-1482545 https://reactome.org/PathwayBrowser/#/R-SCE-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Saccharomyces cerevisiae 57560 R-SCE-1482571 https://reactome.org/PathwayBrowser/#/R-SCE-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Saccharomyces cerevisiae 57560 R-SCE-1482604 https://reactome.org/PathwayBrowser/#/R-SCE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Saccharomyces cerevisiae 57560 R-SCE-1482612 https://reactome.org/PathwayBrowser/#/R-SCE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 57560 R-SCE-1482629 https://reactome.org/PathwayBrowser/#/R-SCE-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Saccharomyces cerevisiae 57560 R-SCE-1482656 https://reactome.org/PathwayBrowser/#/R-SCE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Saccharomyces cerevisiae 57560 R-SCE-1482685 https://reactome.org/PathwayBrowser/#/R-SCE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 57560 R-SCE-1482696 https://reactome.org/PathwayBrowser/#/R-SCE-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Saccharomyces cerevisiae 57560 R-SCE-1482745 https://reactome.org/PathwayBrowser/#/R-SCE-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Saccharomyces cerevisiae 57560 R-SCE-1482759 https://reactome.org/PathwayBrowser/#/R-SCE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Saccharomyces cerevisiae 57560 R-SCE-1482771 https://reactome.org/PathwayBrowser/#/R-SCE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Saccharomyces cerevisiae 57560 R-SCE-1482816 https://reactome.org/PathwayBrowser/#/R-SCE-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Saccharomyces cerevisiae 57560 R-SCE-1482825 https://reactome.org/PathwayBrowser/#/R-SCE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Saccharomyces cerevisiae 57560 R-SCE-1482827 https://reactome.org/PathwayBrowser/#/R-SCE-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Saccharomyces cerevisiae 57560 R-SCE-1482828 https://reactome.org/PathwayBrowser/#/R-SCE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Saccharomyces cerevisiae 57560 R-SCE-1482847 https://reactome.org/PathwayBrowser/#/R-SCE-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Saccharomyces cerevisiae 57560 R-SCE-1482856 https://reactome.org/PathwayBrowser/#/R-SCE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Saccharomyces cerevisiae 57560 R-SCE-1482862 https://reactome.org/PathwayBrowser/#/R-SCE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Saccharomyces cerevisiae 57560 R-SCE-1482868 https://reactome.org/PathwayBrowser/#/R-SCE-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Saccharomyces cerevisiae 57560 R-SCE-1482884 https://reactome.org/PathwayBrowser/#/R-SCE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Saccharomyces cerevisiae 57560 R-SCE-1482892 https://reactome.org/PathwayBrowser/#/R-SCE-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Saccharomyces cerevisiae 57560 R-SCE-1482897 https://reactome.org/PathwayBrowser/#/R-SCE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Saccharomyces cerevisiae 57560 R-SCE-1482900 https://reactome.org/PathwayBrowser/#/R-SCE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Saccharomyces cerevisiae 57560 R-SCE-1482920 https://reactome.org/PathwayBrowser/#/R-SCE-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Saccharomyces cerevisiae 57560 R-SCE-1482932 https://reactome.org/PathwayBrowser/#/R-SCE-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Saccharomyces cerevisiae 57560 R-SCE-6786650 https://reactome.org/PathwayBrowser/#/R-SCE-6786650 DDHD1,2 hydrolyse PA IEA Saccharomyces cerevisiae 57560 R-SCE-6814254 https://reactome.org/PathwayBrowser/#/R-SCE-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Saccharomyces cerevisiae 57560 R-SCE-8952251 https://reactome.org/PathwayBrowser/#/R-SCE-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Saccharomyces cerevisiae 57560 R-SPO-1482545 https://reactome.org/PathwayBrowser/#/R-SPO-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Schizosaccharomyces pombe 57560 R-SPO-1482571 https://reactome.org/PathwayBrowser/#/R-SPO-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Schizosaccharomyces pombe 57560 R-SPO-1482604 https://reactome.org/PathwayBrowser/#/R-SPO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Schizosaccharomyces pombe 57560 R-SPO-1482612 https://reactome.org/PathwayBrowser/#/R-SPO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 57560 R-SPO-1482629 https://reactome.org/PathwayBrowser/#/R-SPO-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Schizosaccharomyces pombe 57560 R-SPO-1482656 https://reactome.org/PathwayBrowser/#/R-SPO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Schizosaccharomyces pombe 57560 R-SPO-1482685 https://reactome.org/PathwayBrowser/#/R-SPO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 57560 R-SPO-1482696 https://reactome.org/PathwayBrowser/#/R-SPO-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Schizosaccharomyces pombe 57560 R-SPO-1482745 https://reactome.org/PathwayBrowser/#/R-SPO-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Schizosaccharomyces pombe 57560 R-SPO-1482759 https://reactome.org/PathwayBrowser/#/R-SPO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Schizosaccharomyces pombe 57560 R-SPO-1482771 https://reactome.org/PathwayBrowser/#/R-SPO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Schizosaccharomyces pombe 57560 R-SPO-1482816 https://reactome.org/PathwayBrowser/#/R-SPO-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Schizosaccharomyces pombe 57560 R-SPO-1482825 https://reactome.org/PathwayBrowser/#/R-SPO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Schizosaccharomyces pombe 57560 R-SPO-1482827 https://reactome.org/PathwayBrowser/#/R-SPO-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Schizosaccharomyces pombe 57560 R-SPO-1482828 https://reactome.org/PathwayBrowser/#/R-SPO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Schizosaccharomyces pombe 57560 R-SPO-1482847 https://reactome.org/PathwayBrowser/#/R-SPO-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Schizosaccharomyces pombe 57560 R-SPO-1482856 https://reactome.org/PathwayBrowser/#/R-SPO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Schizosaccharomyces pombe 57560 R-SPO-1482862 https://reactome.org/PathwayBrowser/#/R-SPO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Schizosaccharomyces pombe 57560 R-SPO-1482868 https://reactome.org/PathwayBrowser/#/R-SPO-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Schizosaccharomyces pombe 57560 R-SPO-1482884 https://reactome.org/PathwayBrowser/#/R-SPO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Schizosaccharomyces pombe 57560 R-SPO-1482892 https://reactome.org/PathwayBrowser/#/R-SPO-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Schizosaccharomyces pombe 57560 R-SPO-1482897 https://reactome.org/PathwayBrowser/#/R-SPO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Schizosaccharomyces pombe 57560 R-SPO-1482900 https://reactome.org/PathwayBrowser/#/R-SPO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Schizosaccharomyces pombe 57560 R-SPO-1482920 https://reactome.org/PathwayBrowser/#/R-SPO-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Schizosaccharomyces pombe 57560 R-SPO-1482932 https://reactome.org/PathwayBrowser/#/R-SPO-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Schizosaccharomyces pombe 57560 R-SPO-6786650 https://reactome.org/PathwayBrowser/#/R-SPO-6786650 DDHD1,2 hydrolyse PA IEA Schizosaccharomyces pombe 57560 R-SPO-6813720 https://reactome.org/PathwayBrowser/#/R-SPO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Schizosaccharomyces pombe 57560 R-SPO-6814254 https://reactome.org/PathwayBrowser/#/R-SPO-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Schizosaccharomyces pombe 57560 R-SSC-1482604 https://reactome.org/PathwayBrowser/#/R-SSC-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Sus scrofa 57560 R-SSC-1482612 https://reactome.org/PathwayBrowser/#/R-SSC-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 57560 R-SSC-1482656 https://reactome.org/PathwayBrowser/#/R-SSC-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Sus scrofa 57560 R-SSC-1482679 https://reactome.org/PathwayBrowser/#/R-SSC-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Sus scrofa 57560 R-SSC-1482685 https://reactome.org/PathwayBrowser/#/R-SSC-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 57560 R-SSC-1482745 https://reactome.org/PathwayBrowser/#/R-SSC-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Sus scrofa 57560 R-SSC-1482759 https://reactome.org/PathwayBrowser/#/R-SSC-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Sus scrofa 57560 R-SSC-1482771 https://reactome.org/PathwayBrowser/#/R-SSC-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Sus scrofa 57560 R-SSC-1482776 https://reactome.org/PathwayBrowser/#/R-SSC-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Sus scrofa 57560 R-SSC-1482777 https://reactome.org/PathwayBrowser/#/R-SSC-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Sus scrofa 57560 R-SSC-1482811 https://reactome.org/PathwayBrowser/#/R-SSC-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Sus scrofa 57560 R-SSC-1482816 https://reactome.org/PathwayBrowser/#/R-SSC-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Sus scrofa 57560 R-SSC-1482825 https://reactome.org/PathwayBrowser/#/R-SSC-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Sus scrofa 57560 R-SSC-1482828 https://reactome.org/PathwayBrowser/#/R-SSC-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Sus scrofa 57560 R-SSC-1482847 https://reactome.org/PathwayBrowser/#/R-SSC-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Sus scrofa 57560 R-SSC-1482856 https://reactome.org/PathwayBrowser/#/R-SSC-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Sus scrofa 57560 R-SSC-1482862 https://reactome.org/PathwayBrowser/#/R-SSC-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Sus scrofa 57560 R-SSC-1482868 https://reactome.org/PathwayBrowser/#/R-SSC-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Sus scrofa 57560 R-SSC-1482884 https://reactome.org/PathwayBrowser/#/R-SSC-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Sus scrofa 57560 R-SSC-1482887 https://reactome.org/PathwayBrowser/#/R-SSC-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Sus scrofa 57560 R-SSC-1482897 https://reactome.org/PathwayBrowser/#/R-SSC-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Sus scrofa 57560 R-SSC-1482900 https://reactome.org/PathwayBrowser/#/R-SSC-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Sus scrofa 57560 R-SSC-1482907 https://reactome.org/PathwayBrowser/#/R-SSC-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Sus scrofa 57560 R-SSC-1482920 https://reactome.org/PathwayBrowser/#/R-SSC-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Sus scrofa 57560 R-SSC-1482932 https://reactome.org/PathwayBrowser/#/R-SSC-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Sus scrofa 57560 R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa 57560 R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa 57560 R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa 57560 R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa 57560 R-SSC-1602399 https://reactome.org/PathwayBrowser/#/R-SSC-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Sus scrofa 57560 R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa 57560 R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa 57560 R-SSC-162729 https://reactome.org/PathwayBrowser/#/R-SSC-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Sus scrofa 57560 R-SSC-5334794 https://reactome.org/PathwayBrowser/#/R-SSC-5334794 FABPs bind LCFAs IEA Sus scrofa 57560 R-SSC-6786650 https://reactome.org/PathwayBrowser/#/R-SSC-6786650 DDHD1,2 hydrolyse PA IEA Sus scrofa 57560 R-SSC-6792445 https://reactome.org/PathwayBrowser/#/R-SSC-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Sus scrofa 57560 R-SSC-6813720 https://reactome.org/PathwayBrowser/#/R-SSC-6813720 NCEH1 hydrolyzes cholesterol esters IEA Sus scrofa 57560 R-SSC-6814254 https://reactome.org/PathwayBrowser/#/R-SSC-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Sus scrofa 57560 R-SSC-8848338 https://reactome.org/PathwayBrowser/#/R-SSC-8848338 PNPLA4 hydrolyzes TAG IEA Sus scrofa 57560 R-SSC-8869425 https://reactome.org/PathwayBrowser/#/R-SSC-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Sus scrofa 57560 R-SSC-8937442 https://reactome.org/PathwayBrowser/#/R-SSC-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Sus scrofa 57560 R-SSC-8952251 https://reactome.org/PathwayBrowser/#/R-SSC-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Sus scrofa 57560 R-XTR-1482604 https://reactome.org/PathwayBrowser/#/R-XTR-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Xenopus tropicalis 57560 R-XTR-1482612 https://reactome.org/PathwayBrowser/#/R-XTR-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 57560 R-XTR-1482656 https://reactome.org/PathwayBrowser/#/R-XTR-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Xenopus tropicalis 57560 R-XTR-1482679 https://reactome.org/PathwayBrowser/#/R-XTR-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Xenopus tropicalis 57560 R-XTR-1482685 https://reactome.org/PathwayBrowser/#/R-XTR-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 57560 R-XTR-1482745 https://reactome.org/PathwayBrowser/#/R-XTR-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Xenopus tropicalis 57560 R-XTR-1482759 https://reactome.org/PathwayBrowser/#/R-XTR-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Xenopus tropicalis 57560 R-XTR-1482771 https://reactome.org/PathwayBrowser/#/R-XTR-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Xenopus tropicalis 57560 R-XTR-1482776 https://reactome.org/PathwayBrowser/#/R-XTR-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Xenopus tropicalis 57560 R-XTR-1482777 https://reactome.org/PathwayBrowser/#/R-XTR-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Xenopus tropicalis 57560 R-XTR-1482811 https://reactome.org/PathwayBrowser/#/R-XTR-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Xenopus tropicalis 57560 R-XTR-1482816 https://reactome.org/PathwayBrowser/#/R-XTR-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Xenopus tropicalis 57560 R-XTR-1482825 https://reactome.org/PathwayBrowser/#/R-XTR-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Xenopus tropicalis 57560 R-XTR-1482828 https://reactome.org/PathwayBrowser/#/R-XTR-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Xenopus tropicalis 57560 R-XTR-1482847 https://reactome.org/PathwayBrowser/#/R-XTR-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Xenopus tropicalis 57560 R-XTR-1482856 https://reactome.org/PathwayBrowser/#/R-XTR-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Xenopus tropicalis 57560 R-XTR-1482862 https://reactome.org/PathwayBrowser/#/R-XTR-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Xenopus tropicalis 57560 R-XTR-1482868 https://reactome.org/PathwayBrowser/#/R-XTR-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Xenopus tropicalis 57560 R-XTR-1482884 https://reactome.org/PathwayBrowser/#/R-XTR-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Xenopus tropicalis 57560 R-XTR-1482887 https://reactome.org/PathwayBrowser/#/R-XTR-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Xenopus tropicalis 57560 R-XTR-1482897 https://reactome.org/PathwayBrowser/#/R-XTR-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Xenopus tropicalis 57560 R-XTR-1482900 https://reactome.org/PathwayBrowser/#/R-XTR-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Xenopus tropicalis 57560 R-XTR-1482907 https://reactome.org/PathwayBrowser/#/R-XTR-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Xenopus tropicalis 57560 R-XTR-1482920 https://reactome.org/PathwayBrowser/#/R-XTR-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Xenopus tropicalis 57560 R-XTR-1602368 https://reactome.org/PathwayBrowser/#/R-XTR-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Xenopus tropicalis 57560 R-XTR-1602374 https://reactome.org/PathwayBrowser/#/R-XTR-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Xenopus tropicalis 57560 R-XTR-1602377 https://reactome.org/PathwayBrowser/#/R-XTR-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Xenopus tropicalis 57560 R-XTR-1602398 https://reactome.org/PathwayBrowser/#/R-XTR-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Xenopus tropicalis 57560 R-XTR-1602417 https://reactome.org/PathwayBrowser/#/R-XTR-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Xenopus tropicalis 57560 R-XTR-1602446 https://reactome.org/PathwayBrowser/#/R-XTR-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Xenopus tropicalis 57560 R-XTR-5334794 https://reactome.org/PathwayBrowser/#/R-XTR-5334794 FABPs bind LCFAs IEA Xenopus tropicalis 57560 R-XTR-6786650 https://reactome.org/PathwayBrowser/#/R-XTR-6786650 DDHD1,2 hydrolyse PA IEA Xenopus tropicalis 57560 R-XTR-6792445 https://reactome.org/PathwayBrowser/#/R-XTR-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Xenopus tropicalis 57560 R-XTR-8848338 https://reactome.org/PathwayBrowser/#/R-XTR-8848338 PNPLA4 hydrolyzes TAG IEA Xenopus tropicalis 57560 R-XTR-8848339 https://reactome.org/PathwayBrowser/#/R-XTR-8848339 PNPLA5 hydrolyzes TAG IEA Xenopus tropicalis 57560 R-XTR-8952251 https://reactome.org/PathwayBrowser/#/R-XTR-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Xenopus tropicalis 57561 R-HSA-9640316 https://reactome.org/PathwayBrowser/#/R-HSA-9640316 DeHA hydrolyses to threonate and oxalate TAS Homo sapiens 57566 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 57566 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 57566 R-BTA-109759 https://reactome.org/PathwayBrowser/#/R-BTA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Bos taurus 57566 R-BTA-110137 https://reactome.org/PathwayBrowser/#/R-BTA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Bos taurus 57566 R-BTA-110138 https://reactome.org/PathwayBrowser/#/R-BTA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 57566 R-BTA-6788798 https://reactome.org/PathwayBrowser/#/R-BTA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 57566 R-BTA-6788810 https://reactome.org/PathwayBrowser/#/R-BTA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 57566 R-BTA-73548 https://reactome.org/PathwayBrowser/#/R-BTA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Bos taurus 57566 R-BTA-73596 https://reactome.org/PathwayBrowser/#/R-BTA-73596 dCMP + H2O => dUMP + NH4+ IEA Bos taurus 57566 R-BTA-73598 https://reactome.org/PathwayBrowser/#/R-BTA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Bos taurus 57566 R-BTA-75125 https://reactome.org/PathwayBrowser/#/R-BTA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Bos taurus 57566 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 57566 R-CEL-110137 https://reactome.org/PathwayBrowser/#/R-CEL-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Caenorhabditis elegans 57566 R-CEL-110138 https://reactome.org/PathwayBrowser/#/R-CEL-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 57566 R-CEL-6788810 https://reactome.org/PathwayBrowser/#/R-CEL-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 57566 R-CEL-73548 https://reactome.org/PathwayBrowser/#/R-CEL-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Caenorhabditis elegans 57566 R-CEL-75125 https://reactome.org/PathwayBrowser/#/R-CEL-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Caenorhabditis elegans 57566 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 57566 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 57566 R-CFA-109759 https://reactome.org/PathwayBrowser/#/R-CFA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Canis familiaris 57566 R-CFA-110137 https://reactome.org/PathwayBrowser/#/R-CFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Canis familiaris 57566 R-CFA-110138 https://reactome.org/PathwayBrowser/#/R-CFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 57566 R-CFA-6788798 https://reactome.org/PathwayBrowser/#/R-CFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 57566 R-CFA-6788810 https://reactome.org/PathwayBrowser/#/R-CFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 57566 R-CFA-73548 https://reactome.org/PathwayBrowser/#/R-CFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Canis familiaris 57566 R-CFA-73596 https://reactome.org/PathwayBrowser/#/R-CFA-73596 dCMP + H2O => dUMP + NH4+ IEA Canis familiaris 57566 R-CFA-73598 https://reactome.org/PathwayBrowser/#/R-CFA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Canis familiaris 57566 R-CFA-75125 https://reactome.org/PathwayBrowser/#/R-CFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Canis familiaris 57566 R-DDI-6788798 https://reactome.org/PathwayBrowser/#/R-DDI-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 57566 R-DDI-6788810 https://reactome.org/PathwayBrowser/#/R-DDI-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 57566 R-DDI-73548 https://reactome.org/PathwayBrowser/#/R-DDI-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Dictyostelium discoideum 57566 R-DDI-75125 https://reactome.org/PathwayBrowser/#/R-DDI-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Dictyostelium discoideum 57566 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 57566 R-DME-109759 https://reactome.org/PathwayBrowser/#/R-DME-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Drosophila melanogaster 57566 R-DME-110137 https://reactome.org/PathwayBrowser/#/R-DME-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Drosophila melanogaster 57566 R-DME-110138 https://reactome.org/PathwayBrowser/#/R-DME-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 57566 R-DME-6788798 https://reactome.org/PathwayBrowser/#/R-DME-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 57566 R-DME-6788810 https://reactome.org/PathwayBrowser/#/R-DME-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 57566 R-DME-73548 https://reactome.org/PathwayBrowser/#/R-DME-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Drosophila melanogaster 57566 R-DME-75125 https://reactome.org/PathwayBrowser/#/R-DME-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Drosophila melanogaster 57566 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 57566 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 57566 R-DRE-110137 https://reactome.org/PathwayBrowser/#/R-DRE-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Danio rerio 57566 R-DRE-110138 https://reactome.org/PathwayBrowser/#/R-DRE-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 57566 R-DRE-6788798 https://reactome.org/PathwayBrowser/#/R-DRE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 57566 R-DRE-6788810 https://reactome.org/PathwayBrowser/#/R-DRE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 57566 R-DRE-73548 https://reactome.org/PathwayBrowser/#/R-DRE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Danio rerio 57566 R-DRE-73596 https://reactome.org/PathwayBrowser/#/R-DRE-73596 dCMP + H2O => dUMP + NH4+ IEA Danio rerio 57566 R-DRE-73598 https://reactome.org/PathwayBrowser/#/R-DRE-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Danio rerio 57566 R-DRE-75125 https://reactome.org/PathwayBrowser/#/R-DRE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Danio rerio 57566 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 57566 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 57566 R-GGA-109759 https://reactome.org/PathwayBrowser/#/R-GGA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Gallus gallus 57566 R-GGA-110137 https://reactome.org/PathwayBrowser/#/R-GGA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Gallus gallus 57566 R-GGA-110138 https://reactome.org/PathwayBrowser/#/R-GGA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 57566 R-GGA-6788798 https://reactome.org/PathwayBrowser/#/R-GGA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 57566 R-GGA-6788810 https://reactome.org/PathwayBrowser/#/R-GGA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 57566 R-GGA-73548 https://reactome.org/PathwayBrowser/#/R-GGA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Gallus gallus 57566 R-GGA-73596 https://reactome.org/PathwayBrowser/#/R-GGA-73596 dCMP + H2O => dUMP + NH4+ IEA Gallus gallus 57566 R-GGA-73598 https://reactome.org/PathwayBrowser/#/R-GGA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Gallus gallus 57566 R-GGA-75125 https://reactome.org/PathwayBrowser/#/R-GGA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Gallus gallus 57566 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 57566 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 57566 R-HSA-109759 https://reactome.org/PathwayBrowser/#/R-HSA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] TAS Homo sapiens 57566 R-HSA-110137 https://reactome.org/PathwayBrowser/#/R-HSA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP TAS Homo sapiens 57566 R-HSA-110138 https://reactome.org/PathwayBrowser/#/R-HSA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 57566 R-HSA-3245943 https://reactome.org/PathwayBrowser/#/R-HSA-3245943 Viral DNA cleavage by TREX1 TAS Homo sapiens 57566 R-HSA-6788798 https://reactome.org/PathwayBrowser/#/R-HSA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 57566 R-HSA-6788810 https://reactome.org/PathwayBrowser/#/R-HSA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 57566 R-HSA-73548 https://reactome.org/PathwayBrowser/#/R-HSA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) TAS Homo sapiens 57566 R-HSA-73596 https://reactome.org/PathwayBrowser/#/R-HSA-73596 dCMP + H2O => dUMP + NH4+ TAS Homo sapiens 57566 R-HSA-73598 https://reactome.org/PathwayBrowser/#/R-HSA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) TAS Homo sapiens 57566 R-HSA-75125 https://reactome.org/PathwayBrowser/#/R-HSA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) TAS Homo sapiens 57566 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 57566 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 57566 R-MMU-109759 https://reactome.org/PathwayBrowser/#/R-MMU-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Mus musculus 57566 R-MMU-110137 https://reactome.org/PathwayBrowser/#/R-MMU-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Mus musculus 57566 R-MMU-110138 https://reactome.org/PathwayBrowser/#/R-MMU-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 57566 R-MMU-6788798 https://reactome.org/PathwayBrowser/#/R-MMU-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 57566 R-MMU-6788810 https://reactome.org/PathwayBrowser/#/R-MMU-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 57566 R-MMU-73548 https://reactome.org/PathwayBrowser/#/R-MMU-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Mus musculus 57566 R-MMU-73596 https://reactome.org/PathwayBrowser/#/R-MMU-73596 dCMP + H2O => dUMP + NH4+ IEA Mus musculus 57566 R-MMU-73598 https://reactome.org/PathwayBrowser/#/R-MMU-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Mus musculus 57566 R-MMU-75125 https://reactome.org/PathwayBrowser/#/R-MMU-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Mus musculus 57566 R-PFA-110137 https://reactome.org/PathwayBrowser/#/R-PFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Plasmodium falciparum 57566 R-PFA-110138 https://reactome.org/PathwayBrowser/#/R-PFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 57566 R-PFA-6788798 https://reactome.org/PathwayBrowser/#/R-PFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 57566 R-PFA-6788810 https://reactome.org/PathwayBrowser/#/R-PFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 57566 R-PFA-73548 https://reactome.org/PathwayBrowser/#/R-PFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Plasmodium falciparum 57566 R-PFA-75125 https://reactome.org/PathwayBrowser/#/R-PFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Plasmodium falciparum 57566 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 57566 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 57566 R-RNO-109759 https://reactome.org/PathwayBrowser/#/R-RNO-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Rattus norvegicus 57566 R-RNO-110137 https://reactome.org/PathwayBrowser/#/R-RNO-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Rattus norvegicus 57566 R-RNO-110138 https://reactome.org/PathwayBrowser/#/R-RNO-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 57566 R-RNO-6788798 https://reactome.org/PathwayBrowser/#/R-RNO-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 57566 R-RNO-6788810 https://reactome.org/PathwayBrowser/#/R-RNO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 57566 R-RNO-73548 https://reactome.org/PathwayBrowser/#/R-RNO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Rattus norvegicus 57566 R-RNO-73596 https://reactome.org/PathwayBrowser/#/R-RNO-73596 dCMP + H2O => dUMP + NH4+ IEA Rattus norvegicus 57566 R-RNO-73598 https://reactome.org/PathwayBrowser/#/R-RNO-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Rattus norvegicus 57566 R-RNO-75125 https://reactome.org/PathwayBrowser/#/R-RNO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Rattus norvegicus 57566 R-SCE-6788798 https://reactome.org/PathwayBrowser/#/R-SCE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 57566 R-SCE-6788810 https://reactome.org/PathwayBrowser/#/R-SCE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 57566 R-SCE-73548 https://reactome.org/PathwayBrowser/#/R-SCE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Saccharomyces cerevisiae 57566 R-SCE-75125 https://reactome.org/PathwayBrowser/#/R-SCE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Saccharomyces cerevisiae 57566 R-SPO-6788810 https://reactome.org/PathwayBrowser/#/R-SPO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Schizosaccharomyces pombe 57566 R-SPO-73548 https://reactome.org/PathwayBrowser/#/R-SPO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Schizosaccharomyces pombe 57566 R-SPO-75125 https://reactome.org/PathwayBrowser/#/R-SPO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Schizosaccharomyces pombe 57566 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 57566 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 57566 R-SSC-109759 https://reactome.org/PathwayBrowser/#/R-SSC-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Sus scrofa 57566 R-SSC-110137 https://reactome.org/PathwayBrowser/#/R-SSC-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Sus scrofa 57566 R-SSC-110138 https://reactome.org/PathwayBrowser/#/R-SSC-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 57566 R-SSC-6788798 https://reactome.org/PathwayBrowser/#/R-SSC-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 57566 R-SSC-6788810 https://reactome.org/PathwayBrowser/#/R-SSC-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 57566 R-SSC-73548 https://reactome.org/PathwayBrowser/#/R-SSC-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Sus scrofa 57566 R-SSC-73596 https://reactome.org/PathwayBrowser/#/R-SSC-73596 dCMP + H2O => dUMP + NH4+ IEA Sus scrofa 57566 R-SSC-75125 https://reactome.org/PathwayBrowser/#/R-SSC-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Sus scrofa 57566 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 57566 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 57566 R-XTR-109759 https://reactome.org/PathwayBrowser/#/R-XTR-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Xenopus tropicalis 57566 R-XTR-110137 https://reactome.org/PathwayBrowser/#/R-XTR-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Xenopus tropicalis 57566 R-XTR-110138 https://reactome.org/PathwayBrowser/#/R-XTR-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 57566 R-XTR-6788798 https://reactome.org/PathwayBrowser/#/R-XTR-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 57566 R-XTR-6788810 https://reactome.org/PathwayBrowser/#/R-XTR-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 57566 R-XTR-73596 https://reactome.org/PathwayBrowser/#/R-XTR-73596 dCMP + H2O => dUMP + NH4+ IEA Xenopus tropicalis 57566 R-XTR-73598 https://reactome.org/PathwayBrowser/#/R-XTR-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Xenopus tropicalis 57567 R-BTA-111524 https://reactome.org/PathwayBrowser/#/R-BTA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Bos taurus 57567 R-BTA-73828 https://reactome.org/PathwayBrowser/#/R-BTA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Bos taurus 57567 R-CEL-111524 https://reactome.org/PathwayBrowser/#/R-CEL-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Caenorhabditis elegans 57567 R-CEL-73828 https://reactome.org/PathwayBrowser/#/R-CEL-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Caenorhabditis elegans 57567 R-CFA-111524 https://reactome.org/PathwayBrowser/#/R-CFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Canis familiaris 57567 R-CFA-73828 https://reactome.org/PathwayBrowser/#/R-CFA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Canis familiaris 57567 R-DDI-111524 https://reactome.org/PathwayBrowser/#/R-DDI-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Dictyostelium discoideum 57567 R-DME-111524 https://reactome.org/PathwayBrowser/#/R-DME-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Drosophila melanogaster 57567 R-DME-73828 https://reactome.org/PathwayBrowser/#/R-DME-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Drosophila melanogaster 57567 R-DRE-111524 https://reactome.org/PathwayBrowser/#/R-DRE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Danio rerio 57567 R-GGA-111524 https://reactome.org/PathwayBrowser/#/R-GGA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Gallus gallus 57567 R-GGA-421197 https://reactome.org/PathwayBrowser/#/R-GGA-421197 adenylosuccinate => adenosine 5'-monophosphate (AMP) + fumarate IEA Gallus gallus 57567 R-GGA-421201 https://reactome.org/PathwayBrowser/#/R-GGA-421201 inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate IEA Gallus gallus 57567 R-GGA-73828 https://reactome.org/PathwayBrowser/#/R-GGA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Gallus gallus 57567 R-HSA-111524 https://reactome.org/PathwayBrowser/#/R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] TAS Homo sapiens 57567 R-HSA-73828 https://reactome.org/PathwayBrowser/#/R-HSA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate TAS Homo sapiens 57567 R-MMU-111519 https://reactome.org/PathwayBrowser/#/R-MMU-111519 inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate TAS Mus musculus 57567 R-MMU-111524 https://reactome.org/PathwayBrowser/#/R-MMU-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Mus musculus 57567 R-MMU-73828 https://reactome.org/PathwayBrowser/#/R-MMU-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Mus musculus 57567 R-PFA-111524 https://reactome.org/PathwayBrowser/#/R-PFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Plasmodium falciparum 57567 R-RNO-111524 https://reactome.org/PathwayBrowser/#/R-RNO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Rattus norvegicus 57567 R-RNO-73828 https://reactome.org/PathwayBrowser/#/R-RNO-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Rattus norvegicus 57567 R-SCE-111524 https://reactome.org/PathwayBrowser/#/R-SCE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Saccharomyces cerevisiae 57567 R-SCE-73828 https://reactome.org/PathwayBrowser/#/R-SCE-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Saccharomyces cerevisiae 57567 R-SPO-111524 https://reactome.org/PathwayBrowser/#/R-SPO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Schizosaccharomyces pombe 57567 R-SPO-73828 https://reactome.org/PathwayBrowser/#/R-SPO-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Schizosaccharomyces pombe 57567 R-SSC-111524 https://reactome.org/PathwayBrowser/#/R-SSC-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Sus scrofa 57567 R-SSC-73828 https://reactome.org/PathwayBrowser/#/R-SSC-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Sus scrofa 57567 R-XTR-111524 https://reactome.org/PathwayBrowser/#/R-XTR-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Xenopus tropicalis 57567 R-XTR-73828 https://reactome.org/PathwayBrowser/#/R-XTR-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate IEA Xenopus tropicalis 57597 R-BTA-1482695 https://reactome.org/PathwayBrowser/#/R-BTA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Bos taurus 57597 R-BTA-188467 https://reactome.org/PathwayBrowser/#/R-BTA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Bos taurus 57597 R-BTA-549112 https://reactome.org/PathwayBrowser/#/R-BTA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Bos taurus 57597 R-BTA-6813740 https://reactome.org/PathwayBrowser/#/R-BTA-6813740 GDE1 hydrolyzes GroPIns IEA Bos taurus 57597 R-BTA-75886 https://reactome.org/PathwayBrowser/#/R-BTA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Bos taurus 57597 R-BTA-75887 https://reactome.org/PathwayBrowser/#/R-BTA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Bos taurus 57597 R-BTA-75889 https://reactome.org/PathwayBrowser/#/R-BTA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Bos taurus 57597 R-CEL-1482695 https://reactome.org/PathwayBrowser/#/R-CEL-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Caenorhabditis elegans 57597 R-CEL-188467 https://reactome.org/PathwayBrowser/#/R-CEL-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Caenorhabditis elegans 57597 R-CEL-549112 https://reactome.org/PathwayBrowser/#/R-CEL-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Caenorhabditis elegans 57597 R-CEL-6813740 https://reactome.org/PathwayBrowser/#/R-CEL-6813740 GDE1 hydrolyzes GroPIns IEA Caenorhabditis elegans 57597 R-CEL-75886 https://reactome.org/PathwayBrowser/#/R-CEL-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Caenorhabditis elegans 57597 R-CEL-75887 https://reactome.org/PathwayBrowser/#/R-CEL-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Caenorhabditis elegans 57597 R-CEL-75889 https://reactome.org/PathwayBrowser/#/R-CEL-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Caenorhabditis elegans 57597 R-CFA-1482695 https://reactome.org/PathwayBrowser/#/R-CFA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Canis familiaris 57597 R-CFA-188467 https://reactome.org/PathwayBrowser/#/R-CFA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Canis familiaris 57597 R-CFA-549112 https://reactome.org/PathwayBrowser/#/R-CFA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Canis familiaris 57597 R-CFA-6813740 https://reactome.org/PathwayBrowser/#/R-CFA-6813740 GDE1 hydrolyzes GroPIns IEA Canis familiaris 57597 R-CFA-75886 https://reactome.org/PathwayBrowser/#/R-CFA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Canis familiaris 57597 R-CFA-75887 https://reactome.org/PathwayBrowser/#/R-CFA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Canis familiaris 57597 R-CFA-75889 https://reactome.org/PathwayBrowser/#/R-CFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Canis familiaris 57597 R-DDI-188467 https://reactome.org/PathwayBrowser/#/R-DDI-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Dictyostelium discoideum 57597 R-DDI-549112 https://reactome.org/PathwayBrowser/#/R-DDI-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Dictyostelium discoideum 57597 R-DDI-75887 https://reactome.org/PathwayBrowser/#/R-DDI-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Dictyostelium discoideum 57597 R-DME-1482695 https://reactome.org/PathwayBrowser/#/R-DME-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Drosophila melanogaster 57597 R-DME-188467 https://reactome.org/PathwayBrowser/#/R-DME-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Drosophila melanogaster 57597 R-DME-549112 https://reactome.org/PathwayBrowser/#/R-DME-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Drosophila melanogaster 57597 R-DME-6813740 https://reactome.org/PathwayBrowser/#/R-DME-6813740 GDE1 hydrolyzes GroPIns IEA Drosophila melanogaster 57597 R-DME-75886 https://reactome.org/PathwayBrowser/#/R-DME-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Drosophila melanogaster 57597 R-DME-75887 https://reactome.org/PathwayBrowser/#/R-DME-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Drosophila melanogaster 57597 R-DME-75889 https://reactome.org/PathwayBrowser/#/R-DME-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Drosophila melanogaster 57597 R-DRE-1482695 https://reactome.org/PathwayBrowser/#/R-DRE-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Danio rerio 57597 R-DRE-549112 https://reactome.org/PathwayBrowser/#/R-DRE-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Danio rerio 57597 R-DRE-6813740 https://reactome.org/PathwayBrowser/#/R-DRE-6813740 GDE1 hydrolyzes GroPIns IEA Danio rerio 57597 R-DRE-75889 https://reactome.org/PathwayBrowser/#/R-DRE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Danio rerio 57597 R-GGA-1482695 https://reactome.org/PathwayBrowser/#/R-GGA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Gallus gallus 57597 R-GGA-188467 https://reactome.org/PathwayBrowser/#/R-GGA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Gallus gallus 57597 R-GGA-549112 https://reactome.org/PathwayBrowser/#/R-GGA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Gallus gallus 57597 R-GGA-6813740 https://reactome.org/PathwayBrowser/#/R-GGA-6813740 GDE1 hydrolyzes GroPIns IEA Gallus gallus 57597 R-GGA-75886 https://reactome.org/PathwayBrowser/#/R-GGA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Gallus gallus 57597 R-GGA-75887 https://reactome.org/PathwayBrowser/#/R-GGA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Gallus gallus 57597 R-GGA-75889 https://reactome.org/PathwayBrowser/#/R-GGA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Gallus gallus 57597 R-HSA-1482695 https://reactome.org/PathwayBrowser/#/R-HSA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) TAS Homo sapiens 57597 R-HSA-1482939 https://reactome.org/PathwayBrowser/#/R-HSA-1482939 CDP-DAG is converted to PGP by PGS1 IEA Homo sapiens 57597 R-HSA-1483107 https://reactome.org/PathwayBrowser/#/R-HSA-1483107 GPETA is hydrolyzed to ETA and G3P by GPCPD1 IEA Homo sapiens 57597 R-HSA-1483116 https://reactome.org/PathwayBrowser/#/R-HSA-1483116 GPCho is hydrolyzed to Cho and G3P by GPCPD1 IEA Homo sapiens 57597 R-HSA-188467 https://reactome.org/PathwayBrowser/#/R-HSA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) TAS Homo sapiens 57597 R-HSA-549112 https://reactome.org/PathwayBrowser/#/R-HSA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 TAS Homo sapiens 57597 R-HSA-6813740 https://reactome.org/PathwayBrowser/#/R-HSA-6813740 GDE1 hydrolyzes GroPIns TAS Homo sapiens 57597 R-HSA-6814132 https://reactome.org/PathwayBrowser/#/R-HSA-6814132 GDPD5 hydrolyzes GPCho IEA Homo sapiens 57597 R-HSA-75886 https://reactome.org/PathwayBrowser/#/R-HSA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] TAS Homo sapiens 57597 R-HSA-75887 https://reactome.org/PathwayBrowser/#/R-HSA-75887 Conversion of Glycerol to Glycerol-3-phosphate TAS Homo sapiens 57597 R-HSA-75889 https://reactome.org/PathwayBrowser/#/R-HSA-75889 DHAP is converted to G3P by GPD1/GPD1L TAS Homo sapiens 57597 R-MMU-1482695 https://reactome.org/PathwayBrowser/#/R-MMU-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Mus musculus 57597 R-MMU-1483112 https://reactome.org/PathwayBrowser/#/R-MMU-1483112 GPCho is hydrolyzed to Cho and G3P by Gpcpd1 TAS Mus musculus 57597 R-MMU-1483231 https://reactome.org/PathwayBrowser/#/R-MMU-1483231 GPETA is hydrolyzed to ETA and G3P by Gpcpd1 TAS Mus musculus 57597 R-MMU-188467 https://reactome.org/PathwayBrowser/#/R-MMU-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Mus musculus 57597 R-MMU-549112 https://reactome.org/PathwayBrowser/#/R-MMU-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Mus musculus 57597 R-MMU-6813740 https://reactome.org/PathwayBrowser/#/R-MMU-6813740 GDE1 hydrolyzes GroPIns IEA Mus musculus 57597 R-MMU-6814137 https://reactome.org/PathwayBrowser/#/R-MMU-6814137 Gdpd5 hydrolyzes GPCho TAS Mus musculus 57597 R-MMU-75886 https://reactome.org/PathwayBrowser/#/R-MMU-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Mus musculus 57597 R-MMU-75887 https://reactome.org/PathwayBrowser/#/R-MMU-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Mus musculus 57597 R-MMU-75889 https://reactome.org/PathwayBrowser/#/R-MMU-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Mus musculus 57597 R-PFA-188467 https://reactome.org/PathwayBrowser/#/R-PFA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Plasmodium falciparum 57597 R-PFA-75887 https://reactome.org/PathwayBrowser/#/R-PFA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Plasmodium falciparum 57597 R-PFA-75889 https://reactome.org/PathwayBrowser/#/R-PFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Plasmodium falciparum 57597 R-RNO-1482695 https://reactome.org/PathwayBrowser/#/R-RNO-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Rattus norvegicus 57597 R-RNO-1482978 https://reactome.org/PathwayBrowser/#/R-RNO-1482978 CDP-DAG is converted to PGP by Pgs1 TAS Rattus norvegicus 57597 R-RNO-188467 https://reactome.org/PathwayBrowser/#/R-RNO-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Rattus norvegicus 57597 R-RNO-549112 https://reactome.org/PathwayBrowser/#/R-RNO-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Rattus norvegicus 57597 R-RNO-6813740 https://reactome.org/PathwayBrowser/#/R-RNO-6813740 GDE1 hydrolyzes GroPIns IEA Rattus norvegicus 57597 R-RNO-75886 https://reactome.org/PathwayBrowser/#/R-RNO-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Rattus norvegicus 57597 R-RNO-75887 https://reactome.org/PathwayBrowser/#/R-RNO-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Rattus norvegicus 57597 R-RNO-75889 https://reactome.org/PathwayBrowser/#/R-RNO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Rattus norvegicus 57597 R-RNO-8955775 https://reactome.org/PathwayBrowser/#/R-RNO-8955775 Pgp:Mg2+ dimer hydrolyses 3PG to glycerol TAS Rattus norvegicus 57597 R-SCE-188467 https://reactome.org/PathwayBrowser/#/R-SCE-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Saccharomyces cerevisiae 57597 R-SCE-75887 https://reactome.org/PathwayBrowser/#/R-SCE-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Saccharomyces cerevisiae 57597 R-SCE-75889 https://reactome.org/PathwayBrowser/#/R-SCE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Saccharomyces cerevisiae 57597 R-SPO-188467 https://reactome.org/PathwayBrowser/#/R-SPO-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Schizosaccharomyces pombe 57597 R-SPO-75889 https://reactome.org/PathwayBrowser/#/R-SPO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Schizosaccharomyces pombe 57597 R-SSC-1482695 https://reactome.org/PathwayBrowser/#/R-SSC-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Sus scrofa 57597 R-SSC-188467 https://reactome.org/PathwayBrowser/#/R-SSC-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Sus scrofa 57597 R-SSC-549112 https://reactome.org/PathwayBrowser/#/R-SSC-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Sus scrofa 57597 R-SSC-6813740 https://reactome.org/PathwayBrowser/#/R-SSC-6813740 GDE1 hydrolyzes GroPIns IEA Sus scrofa 57597 R-SSC-75886 https://reactome.org/PathwayBrowser/#/R-SSC-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Sus scrofa 57597 R-SSC-75887 https://reactome.org/PathwayBrowser/#/R-SSC-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Sus scrofa 57597 R-SSC-75889 https://reactome.org/PathwayBrowser/#/R-SSC-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Sus scrofa 57597 R-XTR-1482695 https://reactome.org/PathwayBrowser/#/R-XTR-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Xenopus tropicalis 57597 R-XTR-188467 https://reactome.org/PathwayBrowser/#/R-XTR-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Xenopus tropicalis 57597 R-XTR-549112 https://reactome.org/PathwayBrowser/#/R-XTR-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Xenopus tropicalis 57597 R-XTR-6813740 https://reactome.org/PathwayBrowser/#/R-XTR-6813740 GDE1 hydrolyzes GroPIns IEA Xenopus tropicalis 57597 R-XTR-75886 https://reactome.org/PathwayBrowser/#/R-XTR-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Xenopus tropicalis 57597 R-XTR-75887 https://reactome.org/PathwayBrowser/#/R-XTR-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Xenopus tropicalis 57597 R-XTR-75889 https://reactome.org/PathwayBrowser/#/R-XTR-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Xenopus tropicalis 57604 R-BTA-6798335 https://reactome.org/PathwayBrowser/#/R-BTA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Bos taurus 57604 R-BTA-70449 https://reactome.org/PathwayBrowser/#/R-BTA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Bos taurus 57604 R-BTA-70482 https://reactome.org/PathwayBrowser/#/R-BTA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Bos taurus 57604 R-BTA-70486 https://reactome.org/PathwayBrowser/#/R-BTA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Bos taurus 57604 R-BTA-71850 https://reactome.org/PathwayBrowser/#/R-BTA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Bos taurus 57604 R-BTA-8955760 https://reactome.org/PathwayBrowser/#/R-BTA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Bos taurus 57604 R-CEL-70449 https://reactome.org/PathwayBrowser/#/R-CEL-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Caenorhabditis elegans 57604 R-CEL-70482 https://reactome.org/PathwayBrowser/#/R-CEL-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Caenorhabditis elegans 57604 R-CEL-70486 https://reactome.org/PathwayBrowser/#/R-CEL-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Caenorhabditis elegans 57604 R-CEL-71850 https://reactome.org/PathwayBrowser/#/R-CEL-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Caenorhabditis elegans 57604 R-CEL-8955760 https://reactome.org/PathwayBrowser/#/R-CEL-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Caenorhabditis elegans 57604 R-CFA-6798335 https://reactome.org/PathwayBrowser/#/R-CFA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Canis familiaris 57604 R-CFA-70449 https://reactome.org/PathwayBrowser/#/R-CFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Canis familiaris 57604 R-CFA-70482 https://reactome.org/PathwayBrowser/#/R-CFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Canis familiaris 57604 R-CFA-70486 https://reactome.org/PathwayBrowser/#/R-CFA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Canis familiaris 57604 R-CFA-71850 https://reactome.org/PathwayBrowser/#/R-CFA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Canis familiaris 57604 R-CFA-8955760 https://reactome.org/PathwayBrowser/#/R-CFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Canis familiaris 57604 R-DDI-6798335 https://reactome.org/PathwayBrowser/#/R-DDI-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Dictyostelium discoideum 57604 R-DDI-70449 https://reactome.org/PathwayBrowser/#/R-DDI-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Dictyostelium discoideum 57604 R-DDI-70482 https://reactome.org/PathwayBrowser/#/R-DDI-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Dictyostelium discoideum 57604 R-DDI-70486 https://reactome.org/PathwayBrowser/#/R-DDI-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Dictyostelium discoideum 57604 R-DDI-71850 https://reactome.org/PathwayBrowser/#/R-DDI-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Dictyostelium discoideum 57604 R-DDI-8955760 https://reactome.org/PathwayBrowser/#/R-DDI-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Dictyostelium discoideum 57604 R-DME-6798335 https://reactome.org/PathwayBrowser/#/R-DME-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Drosophila melanogaster 57604 R-DME-70449 https://reactome.org/PathwayBrowser/#/R-DME-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Drosophila melanogaster 57604 R-DME-70482 https://reactome.org/PathwayBrowser/#/R-DME-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Drosophila melanogaster 57604 R-DME-70486 https://reactome.org/PathwayBrowser/#/R-DME-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Drosophila melanogaster 57604 R-DME-71850 https://reactome.org/PathwayBrowser/#/R-DME-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Drosophila melanogaster 57604 R-DME-8955760 https://reactome.org/PathwayBrowser/#/R-DME-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Drosophila melanogaster 57604 R-DRE-6798335 https://reactome.org/PathwayBrowser/#/R-DRE-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Danio rerio 57604 R-DRE-70449 https://reactome.org/PathwayBrowser/#/R-DRE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Danio rerio 57604 R-DRE-70482 https://reactome.org/PathwayBrowser/#/R-DRE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Danio rerio 57604 R-DRE-70486 https://reactome.org/PathwayBrowser/#/R-DRE-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Danio rerio 57604 R-DRE-71850 https://reactome.org/PathwayBrowser/#/R-DRE-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Danio rerio 57604 R-DRE-8955760 https://reactome.org/PathwayBrowser/#/R-DRE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Danio rerio 57604 R-GGA-352921 https://reactome.org/PathwayBrowser/#/R-GGA-352921 1,3-bisphosphoglycerate + NADH + H+ <=> glyceraldehyde 3-phosphate + NAD+ + phosphate TAS Gallus gallus 57604 R-GGA-352956 https://reactome.org/PathwayBrowser/#/R-GGA-352956 glyceraldehyde 3-phosphate + NAD+ + phosphate <=> 1,3-bisphosphoglycerate + NADH + H+ TAS Gallus gallus 57604 R-GGA-353023 https://reactome.org/PathwayBrowser/#/R-GGA-353023 3-phosphoglycerate + ATP <=> 1,3-bisphosphoglycerate + ADP TAS Gallus gallus 57604 R-GGA-353039 https://reactome.org/PathwayBrowser/#/R-GGA-353039 1,3-bisphosphoglycerate + ADP <=> 3-phosphoglycerate + ATP TAS Gallus gallus 57604 R-GGA-6798335 https://reactome.org/PathwayBrowser/#/R-GGA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Gallus gallus 57604 R-GGA-70449 https://reactome.org/PathwayBrowser/#/R-GGA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Gallus gallus 57604 R-GGA-70482 https://reactome.org/PathwayBrowser/#/R-GGA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Gallus gallus 57604 R-GGA-70486 https://reactome.org/PathwayBrowser/#/R-GGA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Gallus gallus 57604 R-GGA-71850 https://reactome.org/PathwayBrowser/#/R-GGA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Gallus gallus 57604 R-GGA-8955760 https://reactome.org/PathwayBrowser/#/R-GGA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Gallus gallus 57604 R-HSA-6798335 https://reactome.org/PathwayBrowser/#/R-HSA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG TAS Homo sapiens 57604 R-HSA-70449 https://reactome.org/PathwayBrowser/#/R-HSA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ TAS Homo sapiens 57604 R-HSA-70482 https://reactome.org/PathwayBrowser/#/R-HSA-70482 GAPDH tetramers reduce 1,3BPG to GA3P TAS Homo sapiens 57604 R-HSA-70486 https://reactome.org/PathwayBrowser/#/R-HSA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG TAS Homo sapiens 57604 R-HSA-71850 https://reactome.org/PathwayBrowser/#/R-HSA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP TAS Homo sapiens 57604 R-HSA-8955760 https://reactome.org/PathwayBrowser/#/R-HSA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP TAS Homo sapiens 57604 R-MMU-6798335 https://reactome.org/PathwayBrowser/#/R-MMU-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Mus musculus 57604 R-MMU-70449 https://reactome.org/PathwayBrowser/#/R-MMU-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Mus musculus 57604 R-MMU-70482 https://reactome.org/PathwayBrowser/#/R-MMU-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Mus musculus 57604 R-MMU-70486 https://reactome.org/PathwayBrowser/#/R-MMU-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Mus musculus 57604 R-MMU-71850 https://reactome.org/PathwayBrowser/#/R-MMU-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Mus musculus 57604 R-MMU-8955760 https://reactome.org/PathwayBrowser/#/R-MMU-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Mus musculus 57604 R-PFA-6798335 https://reactome.org/PathwayBrowser/#/R-PFA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Plasmodium falciparum 57604 R-PFA-70449 https://reactome.org/PathwayBrowser/#/R-PFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Plasmodium falciparum 57604 R-PFA-70482 https://reactome.org/PathwayBrowser/#/R-PFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Plasmodium falciparum 57604 R-PFA-70486 https://reactome.org/PathwayBrowser/#/R-PFA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Plasmodium falciparum 57604 R-PFA-71850 https://reactome.org/PathwayBrowser/#/R-PFA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Plasmodium falciparum 57604 R-PFA-8955760 https://reactome.org/PathwayBrowser/#/R-PFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Plasmodium falciparum 57604 R-RNO-6798335 https://reactome.org/PathwayBrowser/#/R-RNO-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Rattus norvegicus 57604 R-RNO-70449 https://reactome.org/PathwayBrowser/#/R-RNO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Rattus norvegicus 57604 R-RNO-70482 https://reactome.org/PathwayBrowser/#/R-RNO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Rattus norvegicus 57604 R-RNO-70486 https://reactome.org/PathwayBrowser/#/R-RNO-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Rattus norvegicus 57604 R-RNO-71850 https://reactome.org/PathwayBrowser/#/R-RNO-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Rattus norvegicus 57604 R-RNO-8955760 https://reactome.org/PathwayBrowser/#/R-RNO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Rattus norvegicus 57604 R-SCE-70449 https://reactome.org/PathwayBrowser/#/R-SCE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Saccharomyces cerevisiae 57604 R-SCE-70482 https://reactome.org/PathwayBrowser/#/R-SCE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Saccharomyces cerevisiae 57604 R-SCE-70486 https://reactome.org/PathwayBrowser/#/R-SCE-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Saccharomyces cerevisiae 57604 R-SCE-71850 https://reactome.org/PathwayBrowser/#/R-SCE-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Saccharomyces cerevisiae 57604 R-SCE-8955760 https://reactome.org/PathwayBrowser/#/R-SCE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Saccharomyces cerevisiae 57604 R-SPO-6798335 https://reactome.org/PathwayBrowser/#/R-SPO-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Schizosaccharomyces pombe 57604 R-SPO-70449 https://reactome.org/PathwayBrowser/#/R-SPO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Schizosaccharomyces pombe 57604 R-SPO-70482 https://reactome.org/PathwayBrowser/#/R-SPO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Schizosaccharomyces pombe 57604 R-SPO-70486 https://reactome.org/PathwayBrowser/#/R-SPO-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Schizosaccharomyces pombe 57604 R-SPO-71850 https://reactome.org/PathwayBrowser/#/R-SPO-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Schizosaccharomyces pombe 57604 R-SPO-8955760 https://reactome.org/PathwayBrowser/#/R-SPO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Schizosaccharomyces pombe 57604 R-SSC-6798335 https://reactome.org/PathwayBrowser/#/R-SSC-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Sus scrofa 57604 R-SSC-70449 https://reactome.org/PathwayBrowser/#/R-SSC-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Sus scrofa 57604 R-SSC-70482 https://reactome.org/PathwayBrowser/#/R-SSC-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Sus scrofa 57604 R-SSC-70486 https://reactome.org/PathwayBrowser/#/R-SSC-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Sus scrofa 57604 R-SSC-71850 https://reactome.org/PathwayBrowser/#/R-SSC-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Sus scrofa 57604 R-SSC-8955760 https://reactome.org/PathwayBrowser/#/R-SSC-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Sus scrofa 57604 R-XTR-6798335 https://reactome.org/PathwayBrowser/#/R-XTR-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Xenopus tropicalis 57604 R-XTR-70449 https://reactome.org/PathwayBrowser/#/R-XTR-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Xenopus tropicalis 57604 R-XTR-70482 https://reactome.org/PathwayBrowser/#/R-XTR-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Xenopus tropicalis 57604 R-XTR-8955760 https://reactome.org/PathwayBrowser/#/R-XTR-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Xenopus tropicalis 57613 R-BTA-1482646 https://reactome.org/PathwayBrowser/#/R-BTA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Bos taurus 57613 R-BTA-1482667 https://reactome.org/PathwayBrowser/#/R-BTA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Bos taurus 57613 R-BTA-1482828 https://reactome.org/PathwayBrowser/#/R-BTA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Bos taurus 57613 R-BTA-1482850 https://reactome.org/PathwayBrowser/#/R-BTA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Bos taurus 57613 R-BTA-1482884 https://reactome.org/PathwayBrowser/#/R-BTA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Bos taurus 57613 R-BTA-1482887 https://reactome.org/PathwayBrowser/#/R-BTA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Bos taurus 57613 R-BTA-1482894 https://reactome.org/PathwayBrowser/#/R-BTA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Bos taurus 57613 R-BTA-1482962 https://reactome.org/PathwayBrowser/#/R-BTA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Bos taurus 57613 R-BTA-1483089 https://reactome.org/PathwayBrowser/#/R-BTA-1483089 PE is converted to PS by PTDSS2 IEA Bos taurus 57613 R-BTA-1483174 https://reactome.org/PathwayBrowser/#/R-BTA-1483174 PE is methylated to PC by PEMT IEA Bos taurus 57613 R-BTA-1602398 https://reactome.org/PathwayBrowser/#/R-BTA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Bos taurus 57613 R-BTA-162798 https://reactome.org/PathwayBrowser/#/R-BTA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Bos taurus 57613 R-BTA-5678490 https://reactome.org/PathwayBrowser/#/R-BTA-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Bos taurus 57613 R-BTA-5682377 https://reactome.org/PathwayBrowser/#/R-BTA-5682377 LC3 de-lipidation by ATG4 IEA Bos taurus 57613 R-BTA-5682388 https://reactome.org/PathwayBrowser/#/R-BTA-5682388 Autophagosome maturation IEA Bos taurus 57613 R-BTA-5696358 https://reactome.org/PathwayBrowser/#/R-BTA-5696358 TREM,CD300 binds lipids IEA Bos taurus 57613 R-BTA-8858298 https://reactome.org/PathwayBrowser/#/R-BTA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Bos taurus 57613 R-BTA-939763 https://reactome.org/PathwayBrowser/#/R-BTA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Bos taurus 57613 R-BTA-947591 https://reactome.org/PathwayBrowser/#/R-BTA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Bos taurus 57613 R-CEL-1482646 https://reactome.org/PathwayBrowser/#/R-CEL-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Caenorhabditis elegans 57613 R-CEL-1482667 https://reactome.org/PathwayBrowser/#/R-CEL-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Caenorhabditis elegans 57613 R-CEL-1482850 https://reactome.org/PathwayBrowser/#/R-CEL-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 57613 R-CEL-1482884 https://reactome.org/PathwayBrowser/#/R-CEL-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Caenorhabditis elegans 57613 R-CEL-1482887 https://reactome.org/PathwayBrowser/#/R-CEL-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Caenorhabditis elegans 57613 R-CEL-1482894 https://reactome.org/PathwayBrowser/#/R-CEL-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 57613 R-CEL-1482962 https://reactome.org/PathwayBrowser/#/R-CEL-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Caenorhabditis elegans 57613 R-CEL-1602398 https://reactome.org/PathwayBrowser/#/R-CEL-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Caenorhabditis elegans 57613 R-CEL-162798 https://reactome.org/PathwayBrowser/#/R-CEL-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Caenorhabditis elegans 57613 R-CEL-5678490 https://reactome.org/PathwayBrowser/#/R-CEL-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Caenorhabditis elegans 57613 R-CEL-5682377 https://reactome.org/PathwayBrowser/#/R-CEL-5682377 LC3 de-lipidation by ATG4 IEA Caenorhabditis elegans 57613 R-CEL-5682388 https://reactome.org/PathwayBrowser/#/R-CEL-5682388 Autophagosome maturation IEA Caenorhabditis elegans 57613 R-CEL-939763 https://reactome.org/PathwayBrowser/#/R-CEL-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Caenorhabditis elegans 57613 R-CEL-947591 https://reactome.org/PathwayBrowser/#/R-CEL-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Caenorhabditis elegans 57613 R-CFA-1482646 https://reactome.org/PathwayBrowser/#/R-CFA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Canis familiaris 57613 R-CFA-1482667 https://reactome.org/PathwayBrowser/#/R-CFA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Canis familiaris 57613 R-CFA-1482828 https://reactome.org/PathwayBrowser/#/R-CFA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Canis familiaris 57613 R-CFA-1482850 https://reactome.org/PathwayBrowser/#/R-CFA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Canis familiaris 57613 R-CFA-1482884 https://reactome.org/PathwayBrowser/#/R-CFA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Canis familiaris 57613 R-CFA-1482887 https://reactome.org/PathwayBrowser/#/R-CFA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Canis familiaris 57613 R-CFA-1482894 https://reactome.org/PathwayBrowser/#/R-CFA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Canis familiaris 57613 R-CFA-1482962 https://reactome.org/PathwayBrowser/#/R-CFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Canis familiaris 57613 R-CFA-1483089 https://reactome.org/PathwayBrowser/#/R-CFA-1483089 PE is converted to PS by PTDSS2 IEA Canis familiaris 57613 R-CFA-1483174 https://reactome.org/PathwayBrowser/#/R-CFA-1483174 PE is methylated to PC by PEMT IEA Canis familiaris 57613 R-CFA-1602398 https://reactome.org/PathwayBrowser/#/R-CFA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Canis familiaris 57613 R-CFA-162798 https://reactome.org/PathwayBrowser/#/R-CFA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Canis familiaris 57613 R-CFA-5678490 https://reactome.org/PathwayBrowser/#/R-CFA-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Canis familiaris 57613 R-CFA-5682377 https://reactome.org/PathwayBrowser/#/R-CFA-5682377 LC3 de-lipidation by ATG4 IEA Canis familiaris 57613 R-CFA-5682388 https://reactome.org/PathwayBrowser/#/R-CFA-5682388 Autophagosome maturation IEA Canis familiaris 57613 R-CFA-5696358 https://reactome.org/PathwayBrowser/#/R-CFA-5696358 TREM,CD300 binds lipids IEA Canis familiaris 57613 R-CFA-8858298 https://reactome.org/PathwayBrowser/#/R-CFA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Canis familiaris 57613 R-CFA-939763 https://reactome.org/PathwayBrowser/#/R-CFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Canis familiaris 57613 R-CFA-947591 https://reactome.org/PathwayBrowser/#/R-CFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Canis familiaris 57613 R-DDI-1482646 https://reactome.org/PathwayBrowser/#/R-DDI-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Dictyostelium discoideum 57613 R-DDI-1482667 https://reactome.org/PathwayBrowser/#/R-DDI-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Dictyostelium discoideum 57613 R-DDI-1482850 https://reactome.org/PathwayBrowser/#/R-DDI-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 57613 R-DDI-1482884 https://reactome.org/PathwayBrowser/#/R-DDI-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Dictyostelium discoideum 57613 R-DDI-1482887 https://reactome.org/PathwayBrowser/#/R-DDI-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Dictyostelium discoideum 57613 R-DDI-1482894 https://reactome.org/PathwayBrowser/#/R-DDI-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 57613 R-DDI-1482962 https://reactome.org/PathwayBrowser/#/R-DDI-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Dictyostelium discoideum 57613 R-DDI-1483089 https://reactome.org/PathwayBrowser/#/R-DDI-1483089 PE is converted to PS by PTDSS2 IEA Dictyostelium discoideum 57613 R-DDI-1483174 https://reactome.org/PathwayBrowser/#/R-DDI-1483174 PE is methylated to PC by PEMT IEA Dictyostelium discoideum 57613 R-DDI-162798 https://reactome.org/PathwayBrowser/#/R-DDI-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Dictyostelium discoideum 57613 R-DDI-5678490 https://reactome.org/PathwayBrowser/#/R-DDI-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Dictyostelium discoideum 57613 R-DDI-5682377 https://reactome.org/PathwayBrowser/#/R-DDI-5682377 LC3 de-lipidation by ATG4 IEA Dictyostelium discoideum 57613 R-DDI-5682388 https://reactome.org/PathwayBrowser/#/R-DDI-5682388 Autophagosome maturation IEA Dictyostelium discoideum 57613 R-DDI-939763 https://reactome.org/PathwayBrowser/#/R-DDI-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Dictyostelium discoideum 57613 R-DDI-947591 https://reactome.org/PathwayBrowser/#/R-DDI-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Dictyostelium discoideum 57613 R-DME-1482646 https://reactome.org/PathwayBrowser/#/R-DME-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Drosophila melanogaster 57613 R-DME-1482667 https://reactome.org/PathwayBrowser/#/R-DME-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Drosophila melanogaster 57613 R-DME-1482850 https://reactome.org/PathwayBrowser/#/R-DME-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Drosophila melanogaster 57613 R-DME-1482884 https://reactome.org/PathwayBrowser/#/R-DME-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Drosophila melanogaster 57613 R-DME-1482887 https://reactome.org/PathwayBrowser/#/R-DME-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Drosophila melanogaster 57613 R-DME-1482894 https://reactome.org/PathwayBrowser/#/R-DME-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Drosophila melanogaster 57613 R-DME-1482962 https://reactome.org/PathwayBrowser/#/R-DME-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Drosophila melanogaster 57613 R-DME-1602398 https://reactome.org/PathwayBrowser/#/R-DME-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Drosophila melanogaster 57613 R-DME-162798 https://reactome.org/PathwayBrowser/#/R-DME-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Drosophila melanogaster 57613 R-DME-5678490 https://reactome.org/PathwayBrowser/#/R-DME-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Drosophila melanogaster 57613 R-DME-5682377 https://reactome.org/PathwayBrowser/#/R-DME-5682377 LC3 de-lipidation by ATG4 IEA Drosophila melanogaster 57613 R-DME-5682388 https://reactome.org/PathwayBrowser/#/R-DME-5682388 Autophagosome maturation IEA Drosophila melanogaster 57613 R-DME-939763 https://reactome.org/PathwayBrowser/#/R-DME-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Drosophila melanogaster 57613 R-DME-947591 https://reactome.org/PathwayBrowser/#/R-DME-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Drosophila melanogaster 57613 R-DRE-1482828 https://reactome.org/PathwayBrowser/#/R-DRE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Danio rerio 57613 R-DRE-1482850 https://reactome.org/PathwayBrowser/#/R-DRE-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Danio rerio 57613 R-DRE-1482884 https://reactome.org/PathwayBrowser/#/R-DRE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Danio rerio 57613 R-DRE-1482892 https://reactome.org/PathwayBrowser/#/R-DRE-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Danio rerio 57613 R-DRE-1482894 https://reactome.org/PathwayBrowser/#/R-DRE-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Danio rerio 57613 R-DRE-1482962 https://reactome.org/PathwayBrowser/#/R-DRE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Danio rerio 57613 R-DRE-1483089 https://reactome.org/PathwayBrowser/#/R-DRE-1483089 PE is converted to PS by PTDSS2 IEA Danio rerio 57613 R-DRE-1483174 https://reactome.org/PathwayBrowser/#/R-DRE-1483174 PE is methylated to PC by PEMT IEA Danio rerio 57613 R-DRE-1602398 https://reactome.org/PathwayBrowser/#/R-DRE-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Danio rerio 57613 R-DRE-162798 https://reactome.org/PathwayBrowser/#/R-DRE-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Danio rerio 57613 R-DRE-5682377 https://reactome.org/PathwayBrowser/#/R-DRE-5682377 LC3 de-lipidation by ATG4 IEA Danio rerio 57613 R-DRE-5682388 https://reactome.org/PathwayBrowser/#/R-DRE-5682388 Autophagosome maturation IEA Danio rerio 57613 R-DRE-5696358 https://reactome.org/PathwayBrowser/#/R-DRE-5696358 TREM,CD300 binds lipids IEA Danio rerio 57613 R-DRE-8858298 https://reactome.org/PathwayBrowser/#/R-DRE-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Danio rerio 57613 R-DRE-939763 https://reactome.org/PathwayBrowser/#/R-DRE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Danio rerio 57613 R-DRE-947591 https://reactome.org/PathwayBrowser/#/R-DRE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Danio rerio 57613 R-GGA-1482646 https://reactome.org/PathwayBrowser/#/R-GGA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Gallus gallus 57613 R-GGA-1482667 https://reactome.org/PathwayBrowser/#/R-GGA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Gallus gallus 57613 R-GGA-1482828 https://reactome.org/PathwayBrowser/#/R-GGA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Gallus gallus 57613 R-GGA-1482850 https://reactome.org/PathwayBrowser/#/R-GGA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Gallus gallus 57613 R-GGA-1482884 https://reactome.org/PathwayBrowser/#/R-GGA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Gallus gallus 57613 R-GGA-1482887 https://reactome.org/PathwayBrowser/#/R-GGA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Gallus gallus 57613 R-GGA-1482894 https://reactome.org/PathwayBrowser/#/R-GGA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Gallus gallus 57613 R-GGA-1482962 https://reactome.org/PathwayBrowser/#/R-GGA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Gallus gallus 57613 R-GGA-1483089 https://reactome.org/PathwayBrowser/#/R-GGA-1483089 PE is converted to PS by PTDSS2 IEA Gallus gallus 57613 R-GGA-1483174 https://reactome.org/PathwayBrowser/#/R-GGA-1483174 PE is methylated to PC by PEMT IEA Gallus gallus 57613 R-GGA-1602398 https://reactome.org/PathwayBrowser/#/R-GGA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Gallus gallus 57613 R-GGA-162798 https://reactome.org/PathwayBrowser/#/R-GGA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Gallus gallus 57613 R-GGA-5678490 https://reactome.org/PathwayBrowser/#/R-GGA-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Gallus gallus 57613 R-GGA-5682377 https://reactome.org/PathwayBrowser/#/R-GGA-5682377 LC3 de-lipidation by ATG4 IEA Gallus gallus 57613 R-GGA-5682388 https://reactome.org/PathwayBrowser/#/R-GGA-5682388 Autophagosome maturation IEA Gallus gallus 57613 R-GGA-5696358 https://reactome.org/PathwayBrowser/#/R-GGA-5696358 TREM,CD300 binds lipids IEA Gallus gallus 57613 R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus 57613 R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus 57613 R-HSA-1482646 https://reactome.org/PathwayBrowser/#/R-HSA-1482646 2-acyl LPE is acylated to PE by LPEAT TAS Homo sapiens 57613 R-HSA-1482667 https://reactome.org/PathwayBrowser/#/R-HSA-1482667 1-acyl LPE is acylated to PE by LPEAT TAS Homo sapiens 57613 R-HSA-1482828 https://reactome.org/PathwayBrowser/#/R-HSA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] TAS Homo sapiens 57613 R-HSA-1482850 https://reactome.org/PathwayBrowser/#/R-HSA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) TAS Homo sapiens 57613 R-HSA-1482884 https://reactome.org/PathwayBrowser/#/R-HSA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] TAS Homo sapiens 57613 R-HSA-1482887 https://reactome.org/PathwayBrowser/#/R-HSA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] TAS Homo sapiens 57613 R-HSA-1482892 https://reactome.org/PathwayBrowser/#/R-HSA-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C TAS Homo sapiens 57613 R-HSA-1482894 https://reactome.org/PathwayBrowser/#/R-HSA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) TAS Homo sapiens 57613 R-HSA-1482962 https://reactome.org/PathwayBrowser/#/R-HSA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 TAS Homo sapiens 57613 R-HSA-1483077 https://reactome.org/PathwayBrowser/#/R-HSA-1483077 PE transports from the mitochondrial membrane to the ER IEA Homo sapiens 57613 R-HSA-1483089 https://reactome.org/PathwayBrowser/#/R-HSA-1483089 PE is converted to PS by PTDSS2 TAS Homo sapiens 57613 R-HSA-1483174 https://reactome.org/PathwayBrowser/#/R-HSA-1483174 PE is methylated to PC by PEMT TAS Homo sapiens 57613 R-HSA-1483212 https://reactome.org/PathwayBrowser/#/R-HSA-1483212 PS is decarboxylated to PE by PISD IEA Homo sapiens 57613 R-HSA-1602398 https://reactome.org/PathwayBrowser/#/R-HSA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] TAS Homo sapiens 57613 R-HSA-162798 https://reactome.org/PathwayBrowser/#/R-HSA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol TAS Homo sapiens 57613 R-HSA-163069 https://reactome.org/PathwayBrowser/#/R-HSA-163069 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol IEA Homo sapiens 57613 R-HSA-2466718 https://reactome.org/PathwayBrowser/#/R-HSA-2466718 NRPE dissociates to atRAL and PE TAS Homo sapiens 57613 R-HSA-2466846 https://reactome.org/PathwayBrowser/#/R-HSA-2466846 atRAL can spontaneously react with PE to form NRPE TAS Homo sapiens 57613 R-HSA-5678490 https://reactome.org/PathwayBrowser/#/R-HSA-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE TAS Homo sapiens 57613 R-HSA-5682377 https://reactome.org/PathwayBrowser/#/R-HSA-5682377 LC3 de-lipidation by ATG4 TAS Homo sapiens 57613 R-HSA-5682388 https://reactome.org/PathwayBrowser/#/R-HSA-5682388 Autophagosome maturation TAS Homo sapiens 57613 R-HSA-5696358 https://reactome.org/PathwayBrowser/#/R-HSA-5696358 TREM,CD300 binds lipids TAS Homo sapiens 57613 R-HSA-8858298 https://reactome.org/PathwayBrowser/#/R-HSA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE TAS Homo sapiens 57613 R-HSA-939763 https://reactome.org/PathwayBrowser/#/R-HSA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane TAS Homo sapiens 57613 R-HSA-947591 https://reactome.org/PathwayBrowser/#/R-HSA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane TAS Homo sapiens 57613 R-MMU-1482646 https://reactome.org/PathwayBrowser/#/R-MMU-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Mus musculus 57613 R-MMU-1482667 https://reactome.org/PathwayBrowser/#/R-MMU-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Mus musculus 57613 R-MMU-1482828 https://reactome.org/PathwayBrowser/#/R-MMU-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Mus musculus 57613 R-MMU-1482850 https://reactome.org/PathwayBrowser/#/R-MMU-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Mus musculus 57613 R-MMU-1482884 https://reactome.org/PathwayBrowser/#/R-MMU-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Mus musculus 57613 R-MMU-1482887 https://reactome.org/PathwayBrowser/#/R-MMU-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Mus musculus 57613 R-MMU-1482892 https://reactome.org/PathwayBrowser/#/R-MMU-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Mus musculus 57613 R-MMU-1482894 https://reactome.org/PathwayBrowser/#/R-MMU-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Mus musculus 57613 R-MMU-1482962 https://reactome.org/PathwayBrowser/#/R-MMU-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Mus musculus 57613 R-MMU-1483089 https://reactome.org/PathwayBrowser/#/R-MMU-1483089 PE is converted to PS by PTDSS2 IEA Mus musculus 57613 R-MMU-1483174 https://reactome.org/PathwayBrowser/#/R-MMU-1483174 PE is methylated to PC by PEMT IEA Mus musculus 57613 R-MMU-1602398 https://reactome.org/PathwayBrowser/#/R-MMU-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Mus musculus 57613 R-MMU-162798 https://reactome.org/PathwayBrowser/#/R-MMU-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Mus musculus 57613 R-MMU-162863 https://reactome.org/PathwayBrowser/#/R-MMU-162863 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol TAS Mus musculus 57613 R-MMU-5678490 https://reactome.org/PathwayBrowser/#/R-MMU-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Mus musculus 57613 R-MMU-5682377 https://reactome.org/PathwayBrowser/#/R-MMU-5682377 LC3 de-lipidation by ATG4 IEA Mus musculus 57613 R-MMU-5682388 https://reactome.org/PathwayBrowser/#/R-MMU-5682388 Autophagosome maturation IEA Mus musculus 57613 R-MMU-5696358 https://reactome.org/PathwayBrowser/#/R-MMU-5696358 TREM,CD300 binds lipids IEA Mus musculus 57613 R-MMU-8858298 https://reactome.org/PathwayBrowser/#/R-MMU-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Mus musculus 57613 R-MMU-939763 https://reactome.org/PathwayBrowser/#/R-MMU-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Mus musculus 57613 R-MMU-947591 https://reactome.org/PathwayBrowser/#/R-MMU-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Mus musculus 57613 R-PFA-1482646 https://reactome.org/PathwayBrowser/#/R-PFA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Plasmodium falciparum 57613 R-PFA-1482667 https://reactome.org/PathwayBrowser/#/R-PFA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Plasmodium falciparum 57613 R-PFA-1482962 https://reactome.org/PathwayBrowser/#/R-PFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Plasmodium falciparum 57613 R-PFA-1483089 https://reactome.org/PathwayBrowser/#/R-PFA-1483089 PE is converted to PS by PTDSS2 IEA Plasmodium falciparum 57613 R-PFA-5682377 https://reactome.org/PathwayBrowser/#/R-PFA-5682377 LC3 de-lipidation by ATG4 IEA Plasmodium falciparum 57613 R-PFA-5682388 https://reactome.org/PathwayBrowser/#/R-PFA-5682388 Autophagosome maturation IEA Plasmodium falciparum 57613 R-PFA-939763 https://reactome.org/PathwayBrowser/#/R-PFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Plasmodium falciparum 57613 R-PFA-947591 https://reactome.org/PathwayBrowser/#/R-PFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Plasmodium falciparum 57613 R-RNO-1482646 https://reactome.org/PathwayBrowser/#/R-RNO-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Rattus norvegicus 57613 R-RNO-1482667 https://reactome.org/PathwayBrowser/#/R-RNO-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Rattus norvegicus 57613 R-RNO-1482828 https://reactome.org/PathwayBrowser/#/R-RNO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Rattus norvegicus 57613 R-RNO-1482850 https://reactome.org/PathwayBrowser/#/R-RNO-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Rattus norvegicus 57613 R-RNO-1482884 https://reactome.org/PathwayBrowser/#/R-RNO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Rattus norvegicus 57613 R-RNO-1482887 https://reactome.org/PathwayBrowser/#/R-RNO-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Rattus norvegicus 57613 R-RNO-1482892 https://reactome.org/PathwayBrowser/#/R-RNO-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Rattus norvegicus 57613 R-RNO-1482894 https://reactome.org/PathwayBrowser/#/R-RNO-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Rattus norvegicus 57613 R-RNO-1482962 https://reactome.org/PathwayBrowser/#/R-RNO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Rattus norvegicus 57613 R-RNO-1483065 https://reactome.org/PathwayBrowser/#/R-RNO-1483065 PE transports from the mitochondrial membrane to the ER TAS Rattus norvegicus 57613 R-RNO-1483089 https://reactome.org/PathwayBrowser/#/R-RNO-1483089 PE is converted to PS by PTDSS2 IEA Rattus norvegicus 57613 R-RNO-1483118 https://reactome.org/PathwayBrowser/#/R-RNO-1483118 PS is decarboxylated to PE by Pisd TAS Rattus norvegicus 57613 R-RNO-1483174 https://reactome.org/PathwayBrowser/#/R-RNO-1483174 PE is methylated to PC by PEMT IEA Rattus norvegicus 57613 R-RNO-1602398 https://reactome.org/PathwayBrowser/#/R-RNO-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Rattus norvegicus 57613 R-RNO-162798 https://reactome.org/PathwayBrowser/#/R-RNO-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Rattus norvegicus 57613 R-RNO-5678490 https://reactome.org/PathwayBrowser/#/R-RNO-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Rattus norvegicus 57613 R-RNO-5682377 https://reactome.org/PathwayBrowser/#/R-RNO-5682377 LC3 de-lipidation by ATG4 IEA Rattus norvegicus 57613 R-RNO-5682388 https://reactome.org/PathwayBrowser/#/R-RNO-5682388 Autophagosome maturation IEA Rattus norvegicus 57613 R-RNO-5696358 https://reactome.org/PathwayBrowser/#/R-RNO-5696358 TREM,CD300 binds lipids IEA Rattus norvegicus 57613 R-RNO-8858298 https://reactome.org/PathwayBrowser/#/R-RNO-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Rattus norvegicus 57613 R-RNO-939763 https://reactome.org/PathwayBrowser/#/R-RNO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Rattus norvegicus 57613 R-RNO-947591 https://reactome.org/PathwayBrowser/#/R-RNO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Rattus norvegicus 57613 R-SCE-1482646 https://reactome.org/PathwayBrowser/#/R-SCE-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Saccharomyces cerevisiae 57613 R-SCE-1482667 https://reactome.org/PathwayBrowser/#/R-SCE-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Saccharomyces cerevisiae 57613 R-SCE-1482828 https://reactome.org/PathwayBrowser/#/R-SCE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Saccharomyces cerevisiae 57613 R-SCE-1482850 https://reactome.org/PathwayBrowser/#/R-SCE-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 57613 R-SCE-1482884 https://reactome.org/PathwayBrowser/#/R-SCE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Saccharomyces cerevisiae 57613 R-SCE-1482892 https://reactome.org/PathwayBrowser/#/R-SCE-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Saccharomyces cerevisiae 57613 R-SCE-1482894 https://reactome.org/PathwayBrowser/#/R-SCE-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 57613 R-SCE-1482962 https://reactome.org/PathwayBrowser/#/R-SCE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Saccharomyces cerevisiae 57613 R-SCE-1483174 https://reactome.org/PathwayBrowser/#/R-SCE-1483174 PE is methylated to PC by PEMT IEA Saccharomyces cerevisiae 57613 R-SCE-162798 https://reactome.org/PathwayBrowser/#/R-SCE-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Saccharomyces cerevisiae 57613 R-SCE-5678490 https://reactome.org/PathwayBrowser/#/R-SCE-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Saccharomyces cerevisiae 57613 R-SCE-5682388 https://reactome.org/PathwayBrowser/#/R-SCE-5682388 Autophagosome maturation IEA Saccharomyces cerevisiae 57613 R-SCE-939763 https://reactome.org/PathwayBrowser/#/R-SCE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Saccharomyces cerevisiae 57613 R-SCE-947591 https://reactome.org/PathwayBrowser/#/R-SCE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Saccharomyces cerevisiae 57613 R-SPO-1482646 https://reactome.org/PathwayBrowser/#/R-SPO-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Schizosaccharomyces pombe 57613 R-SPO-1482667 https://reactome.org/PathwayBrowser/#/R-SPO-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Schizosaccharomyces pombe 57613 R-SPO-1482828 https://reactome.org/PathwayBrowser/#/R-SPO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Schizosaccharomyces pombe 57613 R-SPO-1482884 https://reactome.org/PathwayBrowser/#/R-SPO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Schizosaccharomyces pombe 57613 R-SPO-1482892 https://reactome.org/PathwayBrowser/#/R-SPO-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Schizosaccharomyces pombe 57613 R-SPO-1482962 https://reactome.org/PathwayBrowser/#/R-SPO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Schizosaccharomyces pombe 57613 R-SPO-1483174 https://reactome.org/PathwayBrowser/#/R-SPO-1483174 PE is methylated to PC by PEMT IEA Schizosaccharomyces pombe 57613 R-SPO-162798 https://reactome.org/PathwayBrowser/#/R-SPO-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Schizosaccharomyces pombe 57613 R-SPO-5678490 https://reactome.org/PathwayBrowser/#/R-SPO-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Schizosaccharomyces pombe 57613 R-SPO-5682388 https://reactome.org/PathwayBrowser/#/R-SPO-5682388 Autophagosome maturation IEA Schizosaccharomyces pombe 57613 R-SPO-939763 https://reactome.org/PathwayBrowser/#/R-SPO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Schizosaccharomyces pombe 57613 R-SPO-947591 https://reactome.org/PathwayBrowser/#/R-SPO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Schizosaccharomyces pombe 57613 R-SSC-1482646 https://reactome.org/PathwayBrowser/#/R-SSC-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Sus scrofa 57613 R-SSC-1482667 https://reactome.org/PathwayBrowser/#/R-SSC-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Sus scrofa 57613 R-SSC-1482828 https://reactome.org/PathwayBrowser/#/R-SSC-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Sus scrofa 57613 R-SSC-1482850 https://reactome.org/PathwayBrowser/#/R-SSC-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Sus scrofa 57613 R-SSC-1482884 https://reactome.org/PathwayBrowser/#/R-SSC-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Sus scrofa 57613 R-SSC-1482887 https://reactome.org/PathwayBrowser/#/R-SSC-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Sus scrofa 57613 R-SSC-1482894 https://reactome.org/PathwayBrowser/#/R-SSC-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Sus scrofa 57613 R-SSC-1482962 https://reactome.org/PathwayBrowser/#/R-SSC-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Sus scrofa 57613 R-SSC-1483089 https://reactome.org/PathwayBrowser/#/R-SSC-1483089 PE is converted to PS by PTDSS2 IEA Sus scrofa 57613 R-SSC-1483174 https://reactome.org/PathwayBrowser/#/R-SSC-1483174 PE is methylated to PC by PEMT IEA Sus scrofa 57613 R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa 57613 R-SSC-162798 https://reactome.org/PathwayBrowser/#/R-SSC-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Sus scrofa 57613 R-SSC-5678490 https://reactome.org/PathwayBrowser/#/R-SSC-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Sus scrofa 57613 R-SSC-5682377 https://reactome.org/PathwayBrowser/#/R-SSC-5682377 LC3 de-lipidation by ATG4 IEA Sus scrofa 57613 R-SSC-5682388 https://reactome.org/PathwayBrowser/#/R-SSC-5682388 Autophagosome maturation IEA Sus scrofa 57613 R-SSC-5696358 https://reactome.org/PathwayBrowser/#/R-SSC-5696358 TREM,CD300 binds lipids IEA Sus scrofa 57613 R-SSC-8858298 https://reactome.org/PathwayBrowser/#/R-SSC-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Sus scrofa 57613 R-SSC-939763 https://reactome.org/PathwayBrowser/#/R-SSC-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Sus scrofa 57613 R-SSC-947591 https://reactome.org/PathwayBrowser/#/R-SSC-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Sus scrofa 57613 R-XTR-1482646 https://reactome.org/PathwayBrowser/#/R-XTR-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Xenopus tropicalis 57613 R-XTR-1482667 https://reactome.org/PathwayBrowser/#/R-XTR-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Xenopus tropicalis 57613 R-XTR-1482828 https://reactome.org/PathwayBrowser/#/R-XTR-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Xenopus tropicalis 57613 R-XTR-1482850 https://reactome.org/PathwayBrowser/#/R-XTR-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Xenopus tropicalis 57613 R-XTR-1482884 https://reactome.org/PathwayBrowser/#/R-XTR-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Xenopus tropicalis 57613 R-XTR-1482887 https://reactome.org/PathwayBrowser/#/R-XTR-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Xenopus tropicalis 57613 R-XTR-1482894 https://reactome.org/PathwayBrowser/#/R-XTR-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Xenopus tropicalis 57613 R-XTR-1482962 https://reactome.org/PathwayBrowser/#/R-XTR-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Xenopus tropicalis 57613 R-XTR-1483089 https://reactome.org/PathwayBrowser/#/R-XTR-1483089 PE is converted to PS by PTDSS2 IEA Xenopus tropicalis 57613 R-XTR-1483174 https://reactome.org/PathwayBrowser/#/R-XTR-1483174 PE is methylated to PC by PEMT IEA Xenopus tropicalis 57613 R-XTR-1602398 https://reactome.org/PathwayBrowser/#/R-XTR-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Xenopus tropicalis 57613 R-XTR-162798 https://reactome.org/PathwayBrowser/#/R-XTR-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Xenopus tropicalis 57613 R-XTR-5678490 https://reactome.org/PathwayBrowser/#/R-XTR-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Xenopus tropicalis 57613 R-XTR-5682388 https://reactome.org/PathwayBrowser/#/R-XTR-5682388 Autophagosome maturation IEA Xenopus tropicalis 57613 R-XTR-5696358 https://reactome.org/PathwayBrowser/#/R-XTR-5696358 TREM,CD300 binds lipids IEA Xenopus tropicalis 57613 R-XTR-8858298 https://reactome.org/PathwayBrowser/#/R-XTR-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Xenopus tropicalis 57613 R-XTR-939763 https://reactome.org/PathwayBrowser/#/R-XTR-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Xenopus tropicalis 57613 R-XTR-947591 https://reactome.org/PathwayBrowser/#/R-XTR-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Xenopus tropicalis 57627 R-BTA-3777129 https://reactome.org/PathwayBrowser/#/R-BTA-3777129 HDAC3 containing complexes deacetylate histone IEA Bos taurus 57627 R-CFA-3777129 https://reactome.org/PathwayBrowser/#/R-CFA-3777129 HDAC3 containing complexes deacetylate histone IEA Canis familiaris 57627 R-DME-3777129 https://reactome.org/PathwayBrowser/#/R-DME-3777129 HDAC3 containing complexes deacetylate histone IEA Drosophila melanogaster 57627 R-GGA-3777129 https://reactome.org/PathwayBrowser/#/R-GGA-3777129 HDAC3 containing complexes deacetylate histone IEA Gallus gallus 57627 R-HSA-3777129 https://reactome.org/PathwayBrowser/#/R-HSA-3777129 HDAC3 containing complexes deacetylate histone TAS Homo sapiens 57627 R-HSA-9614816 https://reactome.org/PathwayBrowser/#/R-HSA-9614816 Latent Transcriptinally Repressed HCMV Genome TAS Homo sapiens 57627 R-MMU-3777129 https://reactome.org/PathwayBrowser/#/R-MMU-3777129 HDAC3 containing complexes deacetylate histone IEA Mus musculus 57627 R-SCE-3777129 https://reactome.org/PathwayBrowser/#/R-SCE-3777129 HDAC3 containing complexes deacetylate histone IEA Saccharomyces cerevisiae 57627 R-SSC-3777129 https://reactome.org/PathwayBrowser/#/R-SSC-3777129 HDAC3 containing complexes deacetylate histone IEA Sus scrofa 57629 R-BTA-453339 https://reactome.org/PathwayBrowser/#/R-BTA-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Bos taurus 57629 R-BTA-6810464 https://reactome.org/PathwayBrowser/#/R-BTA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Bos taurus 57629 R-BTA-70286 https://reactome.org/PathwayBrowser/#/R-BTA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Bos taurus 57629 R-BTA-70361 https://reactome.org/PathwayBrowser/#/R-BTA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Bos taurus 57629 R-BTA-71590 https://reactome.org/PathwayBrowser/#/R-BTA-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Bos taurus 57629 R-CEL-6810464 https://reactome.org/PathwayBrowser/#/R-CEL-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Caenorhabditis elegans 57629 R-CEL-70286 https://reactome.org/PathwayBrowser/#/R-CEL-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Caenorhabditis elegans 57629 R-CEL-70361 https://reactome.org/PathwayBrowser/#/R-CEL-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Caenorhabditis elegans 57629 R-CEL-9638125 https://reactome.org/PathwayBrowser/#/R-CEL-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Caenorhabditis elegans 57629 R-CEL-9638127 https://reactome.org/PathwayBrowser/#/R-CEL-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Caenorhabditis elegans 57629 R-CFA-453339 https://reactome.org/PathwayBrowser/#/R-CFA-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Canis familiaris 57629 R-CFA-70286 https://reactome.org/PathwayBrowser/#/R-CFA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Canis familiaris 57629 R-CFA-70361 https://reactome.org/PathwayBrowser/#/R-CFA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Canis familiaris 57629 R-CFA-71590 https://reactome.org/PathwayBrowser/#/R-CFA-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Canis familiaris 57629 R-DDI-453339 https://reactome.org/PathwayBrowser/#/R-DDI-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Dictyostelium discoideum 57629 R-DDI-70286 https://reactome.org/PathwayBrowser/#/R-DDI-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Dictyostelium discoideum 57629 R-DDI-71590 https://reactome.org/PathwayBrowser/#/R-DDI-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Dictyostelium discoideum 57629 R-DDI-9638125 https://reactome.org/PathwayBrowser/#/R-DDI-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Dictyostelium discoideum 57629 R-DDI-9638127 https://reactome.org/PathwayBrowser/#/R-DDI-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Dictyostelium discoideum 57629 R-DME-6810464 https://reactome.org/PathwayBrowser/#/R-DME-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Drosophila melanogaster 57629 R-DME-70286 https://reactome.org/PathwayBrowser/#/R-DME-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Drosophila melanogaster 57629 R-DME-70361 https://reactome.org/PathwayBrowser/#/R-DME-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Drosophila melanogaster 57629 R-DME-9638125 https://reactome.org/PathwayBrowser/#/R-DME-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Drosophila melanogaster 57629 R-DME-9638127 https://reactome.org/PathwayBrowser/#/R-DME-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Drosophila melanogaster 57629 R-DRE-6810464 https://reactome.org/PathwayBrowser/#/R-DRE-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Danio rerio 57629 R-DRE-9638125 https://reactome.org/PathwayBrowser/#/R-DRE-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Danio rerio 57629 R-DRE-9638127 https://reactome.org/PathwayBrowser/#/R-DRE-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Danio rerio 57629 R-GGA-6810464 https://reactome.org/PathwayBrowser/#/R-GGA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Gallus gallus 57629 R-GGA-70286 https://reactome.org/PathwayBrowser/#/R-GGA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Gallus gallus 57629 R-GGA-9638125 https://reactome.org/PathwayBrowser/#/R-GGA-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Gallus gallus 57629 R-GGA-9638127 https://reactome.org/PathwayBrowser/#/R-GGA-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Gallus gallus 57629 R-HSA-453339 https://reactome.org/PathwayBrowser/#/R-HSA-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] TAS Homo sapiens 57629 R-HSA-453358 https://reactome.org/PathwayBrowser/#/R-HSA-453358 poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] IEA Homo sapiens 57629 R-HSA-6810464 https://reactome.org/PathwayBrowser/#/R-HSA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP TAS Homo sapiens 57629 R-HSA-70286 https://reactome.org/PathwayBrowser/#/R-HSA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose TAS Homo sapiens 57629 R-HSA-70361 https://reactome.org/PathwayBrowser/#/R-HSA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal TAS Homo sapiens 57629 R-HSA-71515 https://reactome.org/PathwayBrowser/#/R-HSA-71515 glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] IEA Homo sapiens 57629 R-HSA-71590 https://reactome.org/PathwayBrowser/#/R-HSA-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] TAS Homo sapiens 57629 R-HSA-9638125 https://reactome.org/PathwayBrowser/#/R-HSA-9638125 PGM1:Mg2+ isomerises G1P to G6P TAS Homo sapiens 57629 R-HSA-9638127 https://reactome.org/PathwayBrowser/#/R-HSA-9638127 PGM1:Mg2+ isomerises G6P to G1P TAS Homo sapiens 57629 R-MMU-6810464 https://reactome.org/PathwayBrowser/#/R-MMU-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Mus musculus 57629 R-MMU-70286 https://reactome.org/PathwayBrowser/#/R-MMU-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Mus musculus 57629 R-MMU-70361 https://reactome.org/PathwayBrowser/#/R-MMU-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Mus musculus 57629 R-MMU-9638125 https://reactome.org/PathwayBrowser/#/R-MMU-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Mus musculus 57629 R-MMU-9638127 https://reactome.org/PathwayBrowser/#/R-MMU-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Mus musculus 57629 R-RNO-6810464 https://reactome.org/PathwayBrowser/#/R-RNO-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Rattus norvegicus 57629 R-RNO-70286 https://reactome.org/PathwayBrowser/#/R-RNO-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Rattus norvegicus 57629 R-RNO-70361 https://reactome.org/PathwayBrowser/#/R-RNO-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Rattus norvegicus 57629 R-RNO-9638125 https://reactome.org/PathwayBrowser/#/R-RNO-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Rattus norvegicus 57629 R-RNO-9638127 https://reactome.org/PathwayBrowser/#/R-RNO-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Rattus norvegicus 57629 R-SCE-453339 https://reactome.org/PathwayBrowser/#/R-SCE-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Saccharomyces cerevisiae 57629 R-SCE-70286 https://reactome.org/PathwayBrowser/#/R-SCE-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Saccharomyces cerevisiae 57629 R-SCE-71590 https://reactome.org/PathwayBrowser/#/R-SCE-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Saccharomyces cerevisiae 57629 R-SCE-9638125 https://reactome.org/PathwayBrowser/#/R-SCE-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Saccharomyces cerevisiae 57629 R-SCE-9638127 https://reactome.org/PathwayBrowser/#/R-SCE-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Saccharomyces cerevisiae 57629 R-SPO-70286 https://reactome.org/PathwayBrowser/#/R-SPO-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Schizosaccharomyces pombe 57629 R-SPO-9638125 https://reactome.org/PathwayBrowser/#/R-SPO-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Schizosaccharomyces pombe 57629 R-SPO-9638127 https://reactome.org/PathwayBrowser/#/R-SPO-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Schizosaccharomyces pombe 57629 R-SSC-453339 https://reactome.org/PathwayBrowser/#/R-SSC-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Sus scrofa 57629 R-SSC-6810464 https://reactome.org/PathwayBrowser/#/R-SSC-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Sus scrofa 57629 R-SSC-70286 https://reactome.org/PathwayBrowser/#/R-SSC-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Sus scrofa 57629 R-SSC-70361 https://reactome.org/PathwayBrowser/#/R-SSC-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Sus scrofa 57629 R-SSC-71590 https://reactome.org/PathwayBrowser/#/R-SSC-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Sus scrofa 57629 R-XTR-453339 https://reactome.org/PathwayBrowser/#/R-XTR-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Xenopus tropicalis 57629 R-XTR-70286 https://reactome.org/PathwayBrowser/#/R-XTR-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Xenopus tropicalis 57629 R-XTR-71590 https://reactome.org/PathwayBrowser/#/R-XTR-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Xenopus tropicalis 57632 R-BTA-1878002 https://reactome.org/PathwayBrowser/#/R-BTA-1878002 XYLTs transfer Xyl to core protein IEA Bos taurus 57632 R-BTA-5617138 https://reactome.org/PathwayBrowser/#/R-BTA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Bos taurus 57632 R-BTA-742373 https://reactome.org/PathwayBrowser/#/R-BTA-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Bos taurus 57632 R-BTA-9638090 https://reactome.org/PathwayBrowser/#/R-BTA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Bos taurus 57632 R-CEL-1878002 https://reactome.org/PathwayBrowser/#/R-CEL-1878002 XYLTs transfer Xyl to core protein IEA Caenorhabditis elegans 57632 R-CEL-742373 https://reactome.org/PathwayBrowser/#/R-CEL-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Caenorhabditis elegans 57632 R-CFA-1878002 https://reactome.org/PathwayBrowser/#/R-CFA-1878002 XYLTs transfer Xyl to core protein IEA Canis familiaris 57632 R-CFA-5617138 https://reactome.org/PathwayBrowser/#/R-CFA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Canis familiaris 57632 R-CFA-742373 https://reactome.org/PathwayBrowser/#/R-CFA-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Canis familiaris 57632 R-CFA-9638090 https://reactome.org/PathwayBrowser/#/R-CFA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Canis familiaris 57632 R-DDI-742373 https://reactome.org/PathwayBrowser/#/R-DDI-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Dictyostelium discoideum 57632 R-DME-1878002 https://reactome.org/PathwayBrowser/#/R-DME-1878002 XYLTs transfer Xyl to core protein IEA Drosophila melanogaster 57632 R-DME-742373 https://reactome.org/PathwayBrowser/#/R-DME-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Drosophila melanogaster 57632 R-DRE-1878002 https://reactome.org/PathwayBrowser/#/R-DRE-1878002 XYLTs transfer Xyl to core protein IEA Danio rerio 57632 R-DRE-5617138 https://reactome.org/PathwayBrowser/#/R-DRE-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Danio rerio 57632 R-DRE-742373 https://reactome.org/PathwayBrowser/#/R-DRE-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Danio rerio 57632 R-DRE-9638090 https://reactome.org/PathwayBrowser/#/R-DRE-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Danio rerio 57632 R-GGA-1878002 https://reactome.org/PathwayBrowser/#/R-GGA-1878002 XYLTs transfer Xyl to core protein IEA Gallus gallus 57632 R-GGA-742373 https://reactome.org/PathwayBrowser/#/R-GGA-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Gallus gallus 57632 R-HSA-1878002 https://reactome.org/PathwayBrowser/#/R-HSA-1878002 XYLTs transfer Xyl to core protein TAS Homo sapiens 57632 R-HSA-5617138 https://reactome.org/PathwayBrowser/#/R-HSA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA TAS Homo sapiens 57632 R-HSA-6785668 https://reactome.org/PathwayBrowser/#/R-HSA-6785668 Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA TAS Homo sapiens 57632 R-HSA-742373 https://reactome.org/PathwayBrowser/#/R-HSA-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen TAS Homo sapiens 57632 R-HSA-9638090 https://reactome.org/PathwayBrowser/#/R-HSA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA TAS Homo sapiens 57632 R-MMU-1878002 https://reactome.org/PathwayBrowser/#/R-MMU-1878002 XYLTs transfer Xyl to core protein IEA Mus musculus 57632 R-MMU-5617138 https://reactome.org/PathwayBrowser/#/R-MMU-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Mus musculus 57632 R-MMU-742373 https://reactome.org/PathwayBrowser/#/R-MMU-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Mus musculus 57632 R-MMU-9638090 https://reactome.org/PathwayBrowser/#/R-MMU-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Mus musculus 57632 R-RNO-1878002 https://reactome.org/PathwayBrowser/#/R-RNO-1878002 XYLTs transfer Xyl to core protein IEA Rattus norvegicus 57632 R-RNO-5617138 https://reactome.org/PathwayBrowser/#/R-RNO-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Rattus norvegicus 57632 R-RNO-742373 https://reactome.org/PathwayBrowser/#/R-RNO-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Rattus norvegicus 57632 R-RNO-9638090 https://reactome.org/PathwayBrowser/#/R-RNO-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Rattus norvegicus 57632 R-SCE-742373 https://reactome.org/PathwayBrowser/#/R-SCE-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Saccharomyces cerevisiae 57632 R-SPO-742373 https://reactome.org/PathwayBrowser/#/R-SPO-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Schizosaccharomyces pombe 57632 R-SSC-1878002 https://reactome.org/PathwayBrowser/#/R-SSC-1878002 XYLTs transfer Xyl to core protein IEA Sus scrofa 57632 R-SSC-5617138 https://reactome.org/PathwayBrowser/#/R-SSC-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Sus scrofa 57632 R-SSC-742373 https://reactome.org/PathwayBrowser/#/R-SSC-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Sus scrofa 57632 R-SSC-9638090 https://reactome.org/PathwayBrowser/#/R-SSC-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Sus scrofa 57632 R-XTR-1878002 https://reactome.org/PathwayBrowser/#/R-XTR-1878002 XYLTs transfer Xyl to core protein IEA Xenopus tropicalis 57632 R-XTR-5617138 https://reactome.org/PathwayBrowser/#/R-XTR-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Xenopus tropicalis 57632 R-XTR-742373 https://reactome.org/PathwayBrowser/#/R-XTR-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Xenopus tropicalis 57632 R-XTR-9638090 https://reactome.org/PathwayBrowser/#/R-XTR-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Xenopus tropicalis 57634 R-BTA-163751 https://reactome.org/PathwayBrowser/#/R-BTA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Bos taurus 57634 R-BTA-163764 https://reactome.org/PathwayBrowser/#/R-BTA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 57634 R-BTA-449715 https://reactome.org/PathwayBrowser/#/R-BTA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Bos taurus 57634 R-BTA-532549 https://reactome.org/PathwayBrowser/#/R-BTA-532549 MPI isomerises Fru6P to Man6P IEA Bos taurus 57634 R-BTA-5628905 https://reactome.org/PathwayBrowser/#/R-BTA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Bos taurus 57634 R-BTA-6799604 https://reactome.org/PathwayBrowser/#/R-BTA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Bos taurus 57634 R-BTA-70262 https://reactome.org/PathwayBrowser/#/R-BTA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Bos taurus 57634 R-BTA-70467 https://reactome.org/PathwayBrowser/#/R-BTA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Bos taurus 57634 R-BTA-70471 https://reactome.org/PathwayBrowser/#/R-BTA-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Bos taurus 57634 R-BTA-70475 https://reactome.org/PathwayBrowser/#/R-BTA-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Bos taurus 57634 R-BTA-70479 https://reactome.org/PathwayBrowser/#/R-BTA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Bos taurus 57634 R-BTA-71334 https://reactome.org/PathwayBrowser/#/R-BTA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Bos taurus 57634 R-BTA-71335 https://reactome.org/PathwayBrowser/#/R-BTA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Bos taurus 57634 R-BTA-71802 https://reactome.org/PathwayBrowser/#/R-BTA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Bos taurus 57634 R-CEL-163751 https://reactome.org/PathwayBrowser/#/R-CEL-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Caenorhabditis elegans 57634 R-CEL-163764 https://reactome.org/PathwayBrowser/#/R-CEL-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 57634 R-CEL-449715 https://reactome.org/PathwayBrowser/#/R-CEL-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Caenorhabditis elegans 57634 R-CEL-532549 https://reactome.org/PathwayBrowser/#/R-CEL-532549 MPI isomerises Fru6P to Man6P IEA Caenorhabditis elegans 57634 R-CEL-6799604 https://reactome.org/PathwayBrowser/#/R-CEL-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Caenorhabditis elegans 57634 R-CEL-70262 https://reactome.org/PathwayBrowser/#/R-CEL-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Caenorhabditis elegans 57634 R-CEL-70467 https://reactome.org/PathwayBrowser/#/R-CEL-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Caenorhabditis elegans 57634 R-CEL-70471 https://reactome.org/PathwayBrowser/#/R-CEL-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Caenorhabditis elegans 57634 R-CEL-70475 https://reactome.org/PathwayBrowser/#/R-CEL-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Caenorhabditis elegans 57634 R-CEL-70479 https://reactome.org/PathwayBrowser/#/R-CEL-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Caenorhabditis elegans 57634 R-CEL-71334 https://reactome.org/PathwayBrowser/#/R-CEL-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Caenorhabditis elegans 57634 R-CEL-71335 https://reactome.org/PathwayBrowser/#/R-CEL-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Caenorhabditis elegans 57634 R-CEL-71802 https://reactome.org/PathwayBrowser/#/R-CEL-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Caenorhabditis elegans 57634 R-CFA-163751 https://reactome.org/PathwayBrowser/#/R-CFA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Canis familiaris 57634 R-CFA-163764 https://reactome.org/PathwayBrowser/#/R-CFA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 57634 R-CFA-170799 https://reactome.org/PathwayBrowser/#/R-CFA-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Canis familiaris 57634 R-CFA-170824 https://reactome.org/PathwayBrowser/#/R-CFA-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Canis familiaris 57634 R-CFA-449715 https://reactome.org/PathwayBrowser/#/R-CFA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Canis familiaris 57634 R-CFA-532549 https://reactome.org/PathwayBrowser/#/R-CFA-532549 MPI isomerises Fru6P to Man6P IEA Canis familiaris 57634 R-CFA-5628905 https://reactome.org/PathwayBrowser/#/R-CFA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Canis familiaris 57634 R-CFA-6799604 https://reactome.org/PathwayBrowser/#/R-CFA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Canis familiaris 57634 R-CFA-70262 https://reactome.org/PathwayBrowser/#/R-CFA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Canis familiaris 57634 R-CFA-70467 https://reactome.org/PathwayBrowser/#/R-CFA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Canis familiaris 57634 R-CFA-70471 https://reactome.org/PathwayBrowser/#/R-CFA-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Canis familiaris 57634 R-CFA-70475 https://reactome.org/PathwayBrowser/#/R-CFA-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Canis familiaris 57634 R-CFA-70479 https://reactome.org/PathwayBrowser/#/R-CFA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Canis familiaris 57634 R-CFA-71334 https://reactome.org/PathwayBrowser/#/R-CFA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Canis familiaris 57634 R-CFA-71335 https://reactome.org/PathwayBrowser/#/R-CFA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Canis familiaris 57634 R-CFA-71802 https://reactome.org/PathwayBrowser/#/R-CFA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Canis familiaris 57634 R-DDI-163764 https://reactome.org/PathwayBrowser/#/R-DDI-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 57634 R-DDI-449715 https://reactome.org/PathwayBrowser/#/R-DDI-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Dictyostelium discoideum 57634 R-DDI-532549 https://reactome.org/PathwayBrowser/#/R-DDI-532549 MPI isomerises Fru6P to Man6P IEA Dictyostelium discoideum 57634 R-DDI-6799604 https://reactome.org/PathwayBrowser/#/R-DDI-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Dictyostelium discoideum 57634 R-DDI-70262 https://reactome.org/PathwayBrowser/#/R-DDI-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Dictyostelium discoideum 57634 R-DDI-70471 https://reactome.org/PathwayBrowser/#/R-DDI-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Dictyostelium discoideum 57634 R-DDI-70475 https://reactome.org/PathwayBrowser/#/R-DDI-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Dictyostelium discoideum 57634 R-DDI-70479 https://reactome.org/PathwayBrowser/#/R-DDI-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Dictyostelium discoideum 57634 R-DDI-71334 https://reactome.org/PathwayBrowser/#/R-DDI-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Dictyostelium discoideum 57634 R-DDI-71802 https://reactome.org/PathwayBrowser/#/R-DDI-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Dictyostelium discoideum 57634 R-DME-163751 https://reactome.org/PathwayBrowser/#/R-DME-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Drosophila melanogaster 57634 R-DME-163764 https://reactome.org/PathwayBrowser/#/R-DME-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 57634 R-DME-449715 https://reactome.org/PathwayBrowser/#/R-DME-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Drosophila melanogaster 57634 R-DME-532549 https://reactome.org/PathwayBrowser/#/R-DME-532549 MPI isomerises Fru6P to Man6P IEA Drosophila melanogaster 57634 R-DME-6799604 https://reactome.org/PathwayBrowser/#/R-DME-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Drosophila melanogaster 57634 R-DME-70262 https://reactome.org/PathwayBrowser/#/R-DME-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Drosophila melanogaster 57634 R-DME-70467 https://reactome.org/PathwayBrowser/#/R-DME-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Drosophila melanogaster 57634 R-DME-70471 https://reactome.org/PathwayBrowser/#/R-DME-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Drosophila melanogaster 57634 R-DME-70475 https://reactome.org/PathwayBrowser/#/R-DME-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Drosophila melanogaster 57634 R-DME-70479 https://reactome.org/PathwayBrowser/#/R-DME-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Drosophila melanogaster 57634 R-DME-71334 https://reactome.org/PathwayBrowser/#/R-DME-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Drosophila melanogaster 57634 R-DME-71335 https://reactome.org/PathwayBrowser/#/R-DME-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Drosophila melanogaster 57634 R-DME-71802 https://reactome.org/PathwayBrowser/#/R-DME-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Drosophila melanogaster 57634 R-DRE-163764 https://reactome.org/PathwayBrowser/#/R-DRE-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Danio rerio 57634 R-DRE-449715 https://reactome.org/PathwayBrowser/#/R-DRE-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Danio rerio 57634 R-DRE-532549 https://reactome.org/PathwayBrowser/#/R-DRE-532549 MPI isomerises Fru6P to Man6P IEA Danio rerio 57634 R-DRE-5628905 https://reactome.org/PathwayBrowser/#/R-DRE-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Danio rerio 57634 R-DRE-6799604 https://reactome.org/PathwayBrowser/#/R-DRE-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Danio rerio 57634 R-DRE-70467 https://reactome.org/PathwayBrowser/#/R-DRE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Danio rerio 57634 R-DRE-70471 https://reactome.org/PathwayBrowser/#/R-DRE-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Danio rerio 57634 R-DRE-70475 https://reactome.org/PathwayBrowser/#/R-DRE-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Danio rerio 57634 R-DRE-70479 https://reactome.org/PathwayBrowser/#/R-DRE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Danio rerio 57634 R-DRE-71334 https://reactome.org/PathwayBrowser/#/R-DRE-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Danio rerio 57634 R-DRE-71802 https://reactome.org/PathwayBrowser/#/R-DRE-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Danio rerio 57634 R-GGA-163751 https://reactome.org/PathwayBrowser/#/R-GGA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Gallus gallus 57634 R-GGA-163764 https://reactome.org/PathwayBrowser/#/R-GGA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 57634 R-GGA-352872 https://reactome.org/PathwayBrowser/#/R-GGA-352872 fructose 6-phosphate <=> glucose 6-phosphate TAS Gallus gallus 57634 R-GGA-352893 https://reactome.org/PathwayBrowser/#/R-GGA-352893 glucose 6-phosphate <=> fructose 6-phosphate TAS Gallus gallus 57634 R-GGA-352908 https://reactome.org/PathwayBrowser/#/R-GGA-352908 fructose 6-phosphate + ATP => fructose 2,6-bisphosphate + ADP TAS Gallus gallus 57634 R-GGA-352945 https://reactome.org/PathwayBrowser/#/R-GGA-352945 fructose 6-phosphate + ATP => fructose 1,6-bisphosphate + ADP TAS Gallus gallus 57634 R-GGA-372388 https://reactome.org/PathwayBrowser/#/R-GGA-372388 fructose 1,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate TAS Gallus gallus 57634 R-GGA-372425 https://reactome.org/PathwayBrowser/#/R-GGA-372425 fructose 2,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate TAS Gallus gallus 57634 R-GGA-449715 https://reactome.org/PathwayBrowser/#/R-GGA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Gallus gallus 57634 R-GGA-532549 https://reactome.org/PathwayBrowser/#/R-GGA-532549 MPI isomerises Fru6P to Man6P IEA Gallus gallus 57634 R-GGA-5628905 https://reactome.org/PathwayBrowser/#/R-GGA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Gallus gallus 57634 R-GGA-6799604 https://reactome.org/PathwayBrowser/#/R-GGA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Gallus gallus 57634 R-GGA-70262 https://reactome.org/PathwayBrowser/#/R-GGA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Gallus gallus 57634 R-GGA-70467 https://reactome.org/PathwayBrowser/#/R-GGA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Gallus gallus 57634 R-GGA-70471 https://reactome.org/PathwayBrowser/#/R-GGA-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Gallus gallus 57634 R-GGA-70475 https://reactome.org/PathwayBrowser/#/R-GGA-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Gallus gallus 57634 R-GGA-70479 https://reactome.org/PathwayBrowser/#/R-GGA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Gallus gallus 57634 R-GGA-71334 https://reactome.org/PathwayBrowser/#/R-GGA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Gallus gallus 57634 R-GGA-71335 https://reactome.org/PathwayBrowser/#/R-GGA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Gallus gallus 57634 R-GGA-71802 https://reactome.org/PathwayBrowser/#/R-GGA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Gallus gallus 57634 R-HSA-163751 https://reactome.org/PathwayBrowser/#/R-HSA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate TAS Homo sapiens 57634 R-HSA-163764 https://reactome.org/PathwayBrowser/#/R-HSA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 57634 R-HSA-170799 https://reactome.org/PathwayBrowser/#/R-HSA-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) TAS Homo sapiens 57634 R-HSA-170824 https://reactome.org/PathwayBrowser/#/R-HSA-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex TAS Homo sapiens 57634 R-HSA-3781832 https://reactome.org/PathwayBrowser/#/R-HSA-3781832 Defective MPI does not isomerize Fru6P to Man6P TAS Homo sapiens 57634 R-HSA-4085027 https://reactome.org/PathwayBrowser/#/R-HSA-4085027 Defective GFPT1 does not transfer an amino group from L-Gln to F6P to form GlcN6P TAS Homo sapiens 57634 R-HSA-449715 https://reactome.org/PathwayBrowser/#/R-HSA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P TAS Homo sapiens 57634 R-HSA-532549 https://reactome.org/PathwayBrowser/#/R-HSA-532549 MPI isomerises Fru6P to Man6P TAS Homo sapiens 57634 R-HSA-5628905 https://reactome.org/PathwayBrowser/#/R-HSA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate TAS Homo sapiens 57634 R-HSA-5659998 https://reactome.org/PathwayBrowser/#/R-HSA-5659998 Defective TALDO1 does not transform Fru(6)P, E4P to SH7P, GA3P TAS Homo sapiens 57634 R-HSA-6799604 https://reactome.org/PathwayBrowser/#/R-HSA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P TAS Homo sapiens 57634 R-HSA-70262 https://reactome.org/PathwayBrowser/#/R-HSA-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate TAS Homo sapiens 57634 R-HSA-70467 https://reactome.org/PathwayBrowser/#/R-HSA-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP TAS Homo sapiens 57634 R-HSA-70471 https://reactome.org/PathwayBrowser/#/R-HSA-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate TAS Homo sapiens 57634 R-HSA-70475 https://reactome.org/PathwayBrowser/#/R-HSA-70475 GPI dimer isomerizes Fru(6)P to G6P TAS Homo sapiens 57634 R-HSA-70479 https://reactome.org/PathwayBrowser/#/R-HSA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P TAS Homo sapiens 57634 R-HSA-71334 https://reactome.org/PathwayBrowser/#/R-HSA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate TAS Homo sapiens 57634 R-HSA-71335 https://reactome.org/PathwayBrowser/#/R-HSA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate TAS Homo sapiens 57634 R-HSA-71802 https://reactome.org/PathwayBrowser/#/R-HSA-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP TAS Homo sapiens 57634 R-MMU-163751 https://reactome.org/PathwayBrowser/#/R-MMU-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Mus musculus 57634 R-MMU-163764 https://reactome.org/PathwayBrowser/#/R-MMU-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 57634 R-MMU-170799 https://reactome.org/PathwayBrowser/#/R-MMU-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Mus musculus 57634 R-MMU-170824 https://reactome.org/PathwayBrowser/#/R-MMU-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Mus musculus 57634 R-MMU-449715 https://reactome.org/PathwayBrowser/#/R-MMU-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Mus musculus 57634 R-MMU-532549 https://reactome.org/PathwayBrowser/#/R-MMU-532549 MPI isomerises Fru6P to Man6P IEA Mus musculus 57634 R-MMU-5628905 https://reactome.org/PathwayBrowser/#/R-MMU-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Mus musculus 57634 R-MMU-6799604 https://reactome.org/PathwayBrowser/#/R-MMU-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Mus musculus 57634 R-MMU-70262 https://reactome.org/PathwayBrowser/#/R-MMU-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Mus musculus 57634 R-MMU-70467 https://reactome.org/PathwayBrowser/#/R-MMU-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Mus musculus 57634 R-MMU-70471 https://reactome.org/PathwayBrowser/#/R-MMU-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Mus musculus 57634 R-MMU-70475 https://reactome.org/PathwayBrowser/#/R-MMU-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Mus musculus 57634 R-MMU-70479 https://reactome.org/PathwayBrowser/#/R-MMU-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Mus musculus 57634 R-MMU-71334 https://reactome.org/PathwayBrowser/#/R-MMU-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Mus musculus 57634 R-MMU-71335 https://reactome.org/PathwayBrowser/#/R-MMU-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Mus musculus 57634 R-MMU-71802 https://reactome.org/PathwayBrowser/#/R-MMU-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Mus musculus 57634 R-PFA-449715 https://reactome.org/PathwayBrowser/#/R-PFA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Plasmodium falciparum 57634 R-PFA-532549 https://reactome.org/PathwayBrowser/#/R-PFA-532549 MPI isomerises Fru6P to Man6P IEA Plasmodium falciparum 57634 R-PFA-70471 https://reactome.org/PathwayBrowser/#/R-PFA-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Plasmodium falciparum 57634 R-PFA-70475 https://reactome.org/PathwayBrowser/#/R-PFA-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Plasmodium falciparum 57634 R-RNO-163751 https://reactome.org/PathwayBrowser/#/R-RNO-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Rattus norvegicus 57634 R-RNO-163764 https://reactome.org/PathwayBrowser/#/R-RNO-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 57634 R-RNO-170799 https://reactome.org/PathwayBrowser/#/R-RNO-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Rattus norvegicus 57634 R-RNO-170824 https://reactome.org/PathwayBrowser/#/R-RNO-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Rattus norvegicus 57634 R-RNO-449715 https://reactome.org/PathwayBrowser/#/R-RNO-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Rattus norvegicus 57634 R-RNO-532549 https://reactome.org/PathwayBrowser/#/R-RNO-532549 MPI isomerises Fru6P to Man6P IEA Rattus norvegicus 57634 R-RNO-5628905 https://reactome.org/PathwayBrowser/#/R-RNO-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Rattus norvegicus 57634 R-RNO-6799604 https://reactome.org/PathwayBrowser/#/R-RNO-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Rattus norvegicus 57634 R-RNO-70262 https://reactome.org/PathwayBrowser/#/R-RNO-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Rattus norvegicus 57634 R-RNO-70467 https://reactome.org/PathwayBrowser/#/R-RNO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Rattus norvegicus 57634 R-RNO-70471 https://reactome.org/PathwayBrowser/#/R-RNO-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Rattus norvegicus 57634 R-RNO-70475 https://reactome.org/PathwayBrowser/#/R-RNO-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Rattus norvegicus 57634 R-RNO-70479 https://reactome.org/PathwayBrowser/#/R-RNO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Rattus norvegicus 57634 R-RNO-71334 https://reactome.org/PathwayBrowser/#/R-RNO-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Rattus norvegicus 57634 R-RNO-71335 https://reactome.org/PathwayBrowser/#/R-RNO-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Rattus norvegicus 57634 R-RNO-71802 https://reactome.org/PathwayBrowser/#/R-RNO-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Rattus norvegicus 57634 R-SCE-163764 https://reactome.org/PathwayBrowser/#/R-SCE-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Saccharomyces cerevisiae 57634 R-SCE-449715 https://reactome.org/PathwayBrowser/#/R-SCE-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Saccharomyces cerevisiae 57634 R-SCE-532549 https://reactome.org/PathwayBrowser/#/R-SCE-532549 MPI isomerises Fru6P to Man6P IEA Saccharomyces cerevisiae 57634 R-SCE-70262 https://reactome.org/PathwayBrowser/#/R-SCE-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Saccharomyces cerevisiae 57634 R-SCE-70467 https://reactome.org/PathwayBrowser/#/R-SCE-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 57634 R-SCE-70471 https://reactome.org/PathwayBrowser/#/R-SCE-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Saccharomyces cerevisiae 57634 R-SCE-70475 https://reactome.org/PathwayBrowser/#/R-SCE-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Saccharomyces cerevisiae 57634 R-SCE-70479 https://reactome.org/PathwayBrowser/#/R-SCE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Saccharomyces cerevisiae 57634 R-SCE-71334 https://reactome.org/PathwayBrowser/#/R-SCE-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Saccharomyces cerevisiae 57634 R-SCE-71802 https://reactome.org/PathwayBrowser/#/R-SCE-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Saccharomyces cerevisiae 57634 R-SPO-163764 https://reactome.org/PathwayBrowser/#/R-SPO-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Schizosaccharomyces pombe 57634 R-SPO-449715 https://reactome.org/PathwayBrowser/#/R-SPO-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Schizosaccharomyces pombe 57634 R-SPO-532549 https://reactome.org/PathwayBrowser/#/R-SPO-532549 MPI isomerises Fru6P to Man6P IEA Schizosaccharomyces pombe 57634 R-SPO-70262 https://reactome.org/PathwayBrowser/#/R-SPO-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Schizosaccharomyces pombe 57634 R-SPO-70467 https://reactome.org/PathwayBrowser/#/R-SPO-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 57634 R-SPO-70471 https://reactome.org/PathwayBrowser/#/R-SPO-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Schizosaccharomyces pombe 57634 R-SPO-70475 https://reactome.org/PathwayBrowser/#/R-SPO-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Schizosaccharomyces pombe 57634 R-SPO-70479 https://reactome.org/PathwayBrowser/#/R-SPO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Schizosaccharomyces pombe 57634 R-SPO-71334 https://reactome.org/PathwayBrowser/#/R-SPO-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Schizosaccharomyces pombe 57634 R-SPO-71802 https://reactome.org/PathwayBrowser/#/R-SPO-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Schizosaccharomyces pombe 57634 R-SSC-163751 https://reactome.org/PathwayBrowser/#/R-SSC-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Sus scrofa 57634 R-SSC-163764 https://reactome.org/PathwayBrowser/#/R-SSC-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 57634 R-SSC-449715 https://reactome.org/PathwayBrowser/#/R-SSC-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Sus scrofa 57634 R-SSC-532549 https://reactome.org/PathwayBrowser/#/R-SSC-532549 MPI isomerises Fru6P to Man6P IEA Sus scrofa 57634 R-SSC-5628905 https://reactome.org/PathwayBrowser/#/R-SSC-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Sus scrofa 57634 R-SSC-6799604 https://reactome.org/PathwayBrowser/#/R-SSC-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Sus scrofa 57634 R-SSC-70262 https://reactome.org/PathwayBrowser/#/R-SSC-70262 Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate IEA Sus scrofa 57634 R-SSC-70467 https://reactome.org/PathwayBrowser/#/R-SSC-70467 D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP IEA Sus scrofa 57634 R-SSC-70471 https://reactome.org/PathwayBrowser/#/R-SSC-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Sus scrofa 57634 R-SSC-70475 https://reactome.org/PathwayBrowser/#/R-SSC-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Sus scrofa 57634 R-SSC-70479 https://reactome.org/PathwayBrowser/#/R-SSC-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Sus scrofa 57634 R-SSC-71334 https://reactome.org/PathwayBrowser/#/R-SSC-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Sus scrofa 57634 R-SSC-71335 https://reactome.org/PathwayBrowser/#/R-SSC-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Sus scrofa 57634 R-SSC-71802 https://reactome.org/PathwayBrowser/#/R-SSC-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Sus scrofa 57634 R-XTR-163751 https://reactome.org/PathwayBrowser/#/R-XTR-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Xenopus tropicalis 57634 R-XTR-163764 https://reactome.org/PathwayBrowser/#/R-XTR-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 57634 R-XTR-170799 https://reactome.org/PathwayBrowser/#/R-XTR-170799 cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) IEA Xenopus tropicalis 57634 R-XTR-170824 https://reactome.org/PathwayBrowser/#/R-XTR-170824 glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex IEA Xenopus tropicalis 57634 R-XTR-449715 https://reactome.org/PathwayBrowser/#/R-XTR-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Xenopus tropicalis 57634 R-XTR-532549 https://reactome.org/PathwayBrowser/#/R-XTR-532549 MPI isomerises Fru6P to Man6P IEA Xenopus tropicalis 57634 R-XTR-5628905 https://reactome.org/PathwayBrowser/#/R-XTR-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Xenopus tropicalis 57634 R-XTR-6799604 https://reactome.org/PathwayBrowser/#/R-XTR-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Xenopus tropicalis 57634 R-XTR-70471 https://reactome.org/PathwayBrowser/#/R-XTR-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Xenopus tropicalis 57634 R-XTR-70475 https://reactome.org/PathwayBrowser/#/R-XTR-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Xenopus tropicalis 57634 R-XTR-70479 https://reactome.org/PathwayBrowser/#/R-XTR-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Xenopus tropicalis 57634 R-XTR-71334 https://reactome.org/PathwayBrowser/#/R-XTR-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Xenopus tropicalis 57634 R-XTR-71335 https://reactome.org/PathwayBrowser/#/R-XTR-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Xenopus tropicalis 57634 R-XTR-71802 https://reactome.org/PathwayBrowser/#/R-XTR-71802 D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP IEA Xenopus tropicalis 57642 R-BTA-1483002 https://reactome.org/PathwayBrowser/#/R-BTA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Bos taurus 57642 R-BTA-188467 https://reactome.org/PathwayBrowser/#/R-BTA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Bos taurus 57642 R-BTA-70342 https://reactome.org/PathwayBrowser/#/R-BTA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Bos taurus 57642 R-BTA-70454 https://reactome.org/PathwayBrowser/#/R-BTA-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Bos taurus 57642 R-BTA-70481 https://reactome.org/PathwayBrowser/#/R-BTA-70481 TPI1 isomerizes GA3P to DHAP IEA Bos taurus 57642 R-BTA-71495 https://reactome.org/PathwayBrowser/#/R-BTA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Bos taurus 57642 R-BTA-71496 https://reactome.org/PathwayBrowser/#/R-BTA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 57642 R-BTA-75879 https://reactome.org/PathwayBrowser/#/R-BTA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Bos taurus 57642 R-BTA-75889 https://reactome.org/PathwayBrowser/#/R-BTA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Bos taurus 57642 R-CEL-1483002 https://reactome.org/PathwayBrowser/#/R-CEL-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Caenorhabditis elegans 57642 R-CEL-188467 https://reactome.org/PathwayBrowser/#/R-CEL-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Caenorhabditis elegans 57642 R-CEL-70342 https://reactome.org/PathwayBrowser/#/R-CEL-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Caenorhabditis elegans 57642 R-CEL-70454 https://reactome.org/PathwayBrowser/#/R-CEL-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 57642 R-CEL-70481 https://reactome.org/PathwayBrowser/#/R-CEL-70481 TPI1 isomerizes GA3P to DHAP IEA Caenorhabditis elegans 57642 R-CEL-71495 https://reactome.org/PathwayBrowser/#/R-CEL-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Caenorhabditis elegans 57642 R-CEL-71496 https://reactome.org/PathwayBrowser/#/R-CEL-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 57642 R-CEL-75879 https://reactome.org/PathwayBrowser/#/R-CEL-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Caenorhabditis elegans 57642 R-CEL-75889 https://reactome.org/PathwayBrowser/#/R-CEL-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Caenorhabditis elegans 57642 R-CFA-1483002 https://reactome.org/PathwayBrowser/#/R-CFA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Canis familiaris 57642 R-CFA-188467 https://reactome.org/PathwayBrowser/#/R-CFA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Canis familiaris 57642 R-CFA-70342 https://reactome.org/PathwayBrowser/#/R-CFA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Canis familiaris 57642 R-CFA-70454 https://reactome.org/PathwayBrowser/#/R-CFA-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Canis familiaris 57642 R-CFA-70481 https://reactome.org/PathwayBrowser/#/R-CFA-70481 TPI1 isomerizes GA3P to DHAP IEA Canis familiaris 57642 R-CFA-71495 https://reactome.org/PathwayBrowser/#/R-CFA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Canis familiaris 57642 R-CFA-71496 https://reactome.org/PathwayBrowser/#/R-CFA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 57642 R-CFA-75879 https://reactome.org/PathwayBrowser/#/R-CFA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Canis familiaris 57642 R-CFA-75889 https://reactome.org/PathwayBrowser/#/R-CFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Canis familiaris 57642 R-DDI-188467 https://reactome.org/PathwayBrowser/#/R-DDI-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Dictyostelium discoideum 57642 R-DDI-70342 https://reactome.org/PathwayBrowser/#/R-DDI-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Dictyostelium discoideum 57642 R-DDI-70454 https://reactome.org/PathwayBrowser/#/R-DDI-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 57642 R-DDI-70481 https://reactome.org/PathwayBrowser/#/R-DDI-70481 TPI1 isomerizes GA3P to DHAP IEA Dictyostelium discoideum 57642 R-DDI-71495 https://reactome.org/PathwayBrowser/#/R-DDI-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Dictyostelium discoideum 57642 R-DDI-71496 https://reactome.org/PathwayBrowser/#/R-DDI-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 57642 R-DME-1483002 https://reactome.org/PathwayBrowser/#/R-DME-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Drosophila melanogaster 57642 R-DME-188467 https://reactome.org/PathwayBrowser/#/R-DME-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Drosophila melanogaster 57642 R-DME-70342 https://reactome.org/PathwayBrowser/#/R-DME-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Drosophila melanogaster 57642 R-DME-70454 https://reactome.org/PathwayBrowser/#/R-DME-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 57642 R-DME-70481 https://reactome.org/PathwayBrowser/#/R-DME-70481 TPI1 isomerizes GA3P to DHAP IEA Drosophila melanogaster 57642 R-DME-71495 https://reactome.org/PathwayBrowser/#/R-DME-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Drosophila melanogaster 57642 R-DME-71496 https://reactome.org/PathwayBrowser/#/R-DME-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 57642 R-DME-75879 https://reactome.org/PathwayBrowser/#/R-DME-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Drosophila melanogaster 57642 R-DME-75889 https://reactome.org/PathwayBrowser/#/R-DME-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Drosophila melanogaster 57642 R-DRE-70342 https://reactome.org/PathwayBrowser/#/R-DRE-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Danio rerio 57642 R-DRE-70454 https://reactome.org/PathwayBrowser/#/R-DRE-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Danio rerio 57642 R-DRE-70481 https://reactome.org/PathwayBrowser/#/R-DRE-70481 TPI1 isomerizes GA3P to DHAP IEA Danio rerio 57642 R-DRE-71495 https://reactome.org/PathwayBrowser/#/R-DRE-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Danio rerio 57642 R-DRE-71496 https://reactome.org/PathwayBrowser/#/R-DRE-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Danio rerio 57642 R-DRE-75889 https://reactome.org/PathwayBrowser/#/R-DRE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Danio rerio 57642 R-GGA-188467 https://reactome.org/PathwayBrowser/#/R-GGA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Gallus gallus 57642 R-GGA-352914 https://reactome.org/PathwayBrowser/#/R-GGA-352914 glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate TAS Gallus gallus 57642 R-GGA-352927 https://reactome.org/PathwayBrowser/#/R-GGA-352927 dihydroxyacetone phosphate <=> glyceraldehyde 3-phosphate TAS Gallus gallus 57642 R-GGA-352946 https://reactome.org/PathwayBrowser/#/R-GGA-352946 fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate TAS Gallus gallus 57642 R-GGA-352961 https://reactome.org/PathwayBrowser/#/R-GGA-352961 dihydroxyacetone phosphate + glyceraldehyde 3-phosphate <=> fructose 1,6-bisphosphate TAS Gallus gallus 57642 R-GGA-70342 https://reactome.org/PathwayBrowser/#/R-GGA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Gallus gallus 57642 R-GGA-70454 https://reactome.org/PathwayBrowser/#/R-GGA-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Gallus gallus 57642 R-GGA-70481 https://reactome.org/PathwayBrowser/#/R-GGA-70481 TPI1 isomerizes GA3P to DHAP IEA Gallus gallus 57642 R-GGA-71495 https://reactome.org/PathwayBrowser/#/R-GGA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Gallus gallus 57642 R-GGA-71496 https://reactome.org/PathwayBrowser/#/R-GGA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 57642 R-GGA-75889 https://reactome.org/PathwayBrowser/#/R-GGA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Gallus gallus 57642 R-HSA-1483002 https://reactome.org/PathwayBrowser/#/R-HSA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT TAS Homo sapiens 57642 R-HSA-188467 https://reactome.org/PathwayBrowser/#/R-HSA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) TAS Homo sapiens 57642 R-HSA-70342 https://reactome.org/PathwayBrowser/#/R-HSA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP TAS Homo sapiens 57642 R-HSA-70454 https://reactome.org/PathwayBrowser/#/R-HSA-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate TAS Homo sapiens 57642 R-HSA-70481 https://reactome.org/PathwayBrowser/#/R-HSA-70481 TPI1 isomerizes GA3P to DHAP TAS Homo sapiens 57642 R-HSA-71495 https://reactome.org/PathwayBrowser/#/R-HSA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP TAS Homo sapiens 57642 R-HSA-71496 https://reactome.org/PathwayBrowser/#/R-HSA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 57642 R-HSA-75879 https://reactome.org/PathwayBrowser/#/R-HSA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH TAS Homo sapiens 57642 R-HSA-75889 https://reactome.org/PathwayBrowser/#/R-HSA-75889 DHAP is converted to G3P by GPD1/GPD1L TAS Homo sapiens 57642 R-MMU-1483002 https://reactome.org/PathwayBrowser/#/R-MMU-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Mus musculus 57642 R-MMU-188467 https://reactome.org/PathwayBrowser/#/R-MMU-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Mus musculus 57642 R-MMU-70342 https://reactome.org/PathwayBrowser/#/R-MMU-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Mus musculus 57642 R-MMU-70454 https://reactome.org/PathwayBrowser/#/R-MMU-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Mus musculus 57642 R-MMU-70481 https://reactome.org/PathwayBrowser/#/R-MMU-70481 TPI1 isomerizes GA3P to DHAP IEA Mus musculus 57642 R-MMU-71495 https://reactome.org/PathwayBrowser/#/R-MMU-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Mus musculus 57642 R-MMU-71496 https://reactome.org/PathwayBrowser/#/R-MMU-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 57642 R-MMU-75879 https://reactome.org/PathwayBrowser/#/R-MMU-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Mus musculus 57642 R-MMU-75889 https://reactome.org/PathwayBrowser/#/R-MMU-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Mus musculus 57642 R-PFA-188467 https://reactome.org/PathwayBrowser/#/R-PFA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Plasmodium falciparum 57642 R-PFA-70342 https://reactome.org/PathwayBrowser/#/R-PFA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Plasmodium falciparum 57642 R-PFA-70454 https://reactome.org/PathwayBrowser/#/R-PFA-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Plasmodium falciparum 57642 R-PFA-70481 https://reactome.org/PathwayBrowser/#/R-PFA-70481 TPI1 isomerizes GA3P to DHAP IEA Plasmodium falciparum 57642 R-PFA-71495 https://reactome.org/PathwayBrowser/#/R-PFA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Plasmodium falciparum 57642 R-PFA-71496 https://reactome.org/PathwayBrowser/#/R-PFA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Plasmodium falciparum 57642 R-PFA-75889 https://reactome.org/PathwayBrowser/#/R-PFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Plasmodium falciparum 57642 R-RNO-1483002 https://reactome.org/PathwayBrowser/#/R-RNO-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Rattus norvegicus 57642 R-RNO-188467 https://reactome.org/PathwayBrowser/#/R-RNO-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Rattus norvegicus 57642 R-RNO-70342 https://reactome.org/PathwayBrowser/#/R-RNO-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Rattus norvegicus 57642 R-RNO-70454 https://reactome.org/PathwayBrowser/#/R-RNO-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 57642 R-RNO-70481 https://reactome.org/PathwayBrowser/#/R-RNO-70481 TPI1 isomerizes GA3P to DHAP IEA Rattus norvegicus 57642 R-RNO-71495 https://reactome.org/PathwayBrowser/#/R-RNO-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Rattus norvegicus 57642 R-RNO-71496 https://reactome.org/PathwayBrowser/#/R-RNO-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 57642 R-RNO-75879 https://reactome.org/PathwayBrowser/#/R-RNO-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Rattus norvegicus 57642 R-RNO-75889 https://reactome.org/PathwayBrowser/#/R-RNO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Rattus norvegicus 57642 R-SCE-188467 https://reactome.org/PathwayBrowser/#/R-SCE-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Saccharomyces cerevisiae 57642 R-SCE-70454 https://reactome.org/PathwayBrowser/#/R-SCE-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Saccharomyces cerevisiae 57642 R-SCE-70481 https://reactome.org/PathwayBrowser/#/R-SCE-70481 TPI1 isomerizes GA3P to DHAP IEA Saccharomyces cerevisiae 57642 R-SCE-75889 https://reactome.org/PathwayBrowser/#/R-SCE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Saccharomyces cerevisiae 57642 R-SPO-188467 https://reactome.org/PathwayBrowser/#/R-SPO-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Schizosaccharomyces pombe 57642 R-SPO-70454 https://reactome.org/PathwayBrowser/#/R-SPO-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Schizosaccharomyces pombe 57642 R-SPO-70481 https://reactome.org/PathwayBrowser/#/R-SPO-70481 TPI1 isomerizes GA3P to DHAP IEA Schizosaccharomyces pombe 57642 R-SPO-75889 https://reactome.org/PathwayBrowser/#/R-SPO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Schizosaccharomyces pombe 57642 R-SSC-1483002 https://reactome.org/PathwayBrowser/#/R-SSC-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Sus scrofa 57642 R-SSC-188467 https://reactome.org/PathwayBrowser/#/R-SSC-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Sus scrofa 57642 R-SSC-70342 https://reactome.org/PathwayBrowser/#/R-SSC-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Sus scrofa 57642 R-SSC-70454 https://reactome.org/PathwayBrowser/#/R-SSC-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Sus scrofa 57642 R-SSC-70481 https://reactome.org/PathwayBrowser/#/R-SSC-70481 TPI1 isomerizes GA3P to DHAP IEA Sus scrofa 57642 R-SSC-71495 https://reactome.org/PathwayBrowser/#/R-SSC-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Sus scrofa 57642 R-SSC-71496 https://reactome.org/PathwayBrowser/#/R-SSC-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 57642 R-SSC-75879 https://reactome.org/PathwayBrowser/#/R-SSC-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Sus scrofa 57642 R-SSC-75889 https://reactome.org/PathwayBrowser/#/R-SSC-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Sus scrofa 57642 R-XTR-1483002 https://reactome.org/PathwayBrowser/#/R-XTR-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Xenopus tropicalis 57642 R-XTR-188467 https://reactome.org/PathwayBrowser/#/R-XTR-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Xenopus tropicalis 57642 R-XTR-70342 https://reactome.org/PathwayBrowser/#/R-XTR-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Xenopus tropicalis 57642 R-XTR-70454 https://reactome.org/PathwayBrowser/#/R-XTR-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 57642 R-XTR-70481 https://reactome.org/PathwayBrowser/#/R-XTR-70481 TPI1 isomerizes GA3P to DHAP IEA Xenopus tropicalis 57642 R-XTR-71495 https://reactome.org/PathwayBrowser/#/R-XTR-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Xenopus tropicalis 57642 R-XTR-71496 https://reactome.org/PathwayBrowser/#/R-XTR-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 57642 R-XTR-75879 https://reactome.org/PathwayBrowser/#/R-XTR-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Xenopus tropicalis 57642 R-XTR-75889 https://reactome.org/PathwayBrowser/#/R-XTR-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Xenopus tropicalis 57643 R-BTA-111881 https://reactome.org/PathwayBrowser/#/R-BTA-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Bos taurus 57643 R-BTA-111883 https://reactome.org/PathwayBrowser/#/R-BTA-111883 Hydrolysis of phosphatidylcholine IEA Bos taurus 57643 R-BTA-1482533 https://reactome.org/PathwayBrowser/#/R-BTA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Bos taurus 57643 R-BTA-1482547 https://reactome.org/PathwayBrowser/#/R-BTA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Bos taurus 57643 R-BTA-1482781 https://reactome.org/PathwayBrowser/#/R-BTA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Bos taurus 57643 R-BTA-1482794 https://reactome.org/PathwayBrowser/#/R-BTA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Bos taurus 57643 R-BTA-1482816 https://reactome.org/PathwayBrowser/#/R-BTA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Bos taurus 57643 R-BTA-1482856 https://reactome.org/PathwayBrowser/#/R-BTA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Bos taurus 57643 R-BTA-1482862 https://reactome.org/PathwayBrowser/#/R-BTA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Bos taurus 57643 R-BTA-1482961 https://reactome.org/PathwayBrowser/#/R-BTA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Bos taurus 57643 R-BTA-1482973 https://reactome.org/PathwayBrowser/#/R-BTA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Bos taurus 57643 R-BTA-1483087 https://reactome.org/PathwayBrowser/#/R-BTA-1483087 PI is exchanged with PC by PITPNB IEA Bos taurus 57643 R-BTA-1483174 https://reactome.org/PathwayBrowser/#/R-BTA-1483174 PE is methylated to PC by PEMT IEA Bos taurus 57643 R-BTA-1483182 https://reactome.org/PathwayBrowser/#/R-BTA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Bos taurus 57643 R-BTA-1483186 https://reactome.org/PathwayBrowser/#/R-BTA-1483186 PC is converted to PS by PTDSS1 IEA Bos taurus 57643 R-BTA-1483211 https://reactome.org/PathwayBrowser/#/R-BTA-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Bos taurus 57643 R-BTA-1483219 https://reactome.org/PathwayBrowser/#/R-BTA-1483219 PC is exchanged with PI by PITPNB IEA Bos taurus 57643 R-BTA-1602399 https://reactome.org/PathwayBrowser/#/R-BTA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Bos taurus 57643 R-BTA-1602417 https://reactome.org/PathwayBrowser/#/R-BTA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Bos taurus 57643 R-BTA-2029471 https://reactome.org/PathwayBrowser/#/R-BTA-2029471 Hydrolysis of PC to PA by PLD IEA Bos taurus 57643 R-BTA-2029475 https://reactome.org/PathwayBrowser/#/R-BTA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Bos taurus 57643 R-BTA-264695 https://reactome.org/PathwayBrowser/#/R-BTA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Bos taurus 57643 R-BTA-429786 https://reactome.org/PathwayBrowser/#/R-BTA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Bos taurus 57643 R-BTA-429798 https://reactome.org/PathwayBrowser/#/R-BTA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Bos taurus 57643 R-BTA-5678706 https://reactome.org/PathwayBrowser/#/R-BTA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Bos taurus 57643 R-BTA-5683714 https://reactome.org/PathwayBrowser/#/R-BTA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Bos taurus 57643 R-BTA-5684862 https://reactome.org/PathwayBrowser/#/R-BTA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Bos taurus 57643 R-BTA-8848484 https://reactome.org/PathwayBrowser/#/R-BTA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Bos taurus 57643 R-BTA-8849345 https://reactome.org/PathwayBrowser/#/R-BTA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Bos taurus 57643 R-BTA-8858298 https://reactome.org/PathwayBrowser/#/R-BTA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Bos taurus 57643 R-BTA-8873794 https://reactome.org/PathwayBrowser/#/R-BTA-8873794 PCTP binds PC IEA Bos taurus 57643 R-BTA-8873834 https://reactome.org/PathwayBrowser/#/R-BTA-8873834 STARD10 transports PC from ER membrane to lamellar body membrane IEA Bos taurus 57643 R-BTA-8873923 https://reactome.org/PathwayBrowser/#/R-BTA-8873923 STARD10 binds LPCAT1 and PC IEA Bos taurus 57643 R-BTA-8877153 https://reactome.org/PathwayBrowser/#/R-BTA-8877153 STARD7 binds PC IEA Bos taurus 57643 R-CEL-1482533 https://reactome.org/PathwayBrowser/#/R-CEL-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Caenorhabditis elegans 57643 R-CEL-1482547 https://reactome.org/PathwayBrowser/#/R-CEL-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Caenorhabditis elegans 57643 R-CEL-1482781 https://reactome.org/PathwayBrowser/#/R-CEL-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 57643 R-CEL-1482794 https://reactome.org/PathwayBrowser/#/R-CEL-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 57643 R-CEL-1482816 https://reactome.org/PathwayBrowser/#/R-CEL-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Caenorhabditis elegans 57643 R-CEL-1482856 https://reactome.org/PathwayBrowser/#/R-CEL-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Caenorhabditis elegans 57643 R-CEL-1482961 https://reactome.org/PathwayBrowser/#/R-CEL-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Caenorhabditis elegans 57643 R-CEL-1482973 https://reactome.org/PathwayBrowser/#/R-CEL-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Caenorhabditis elegans 57643 R-CEL-1483087 https://reactome.org/PathwayBrowser/#/R-CEL-1483087 PI is exchanged with PC by PITPNB IEA Caenorhabditis elegans 57643 R-CEL-1483182 https://reactome.org/PathwayBrowser/#/R-CEL-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Caenorhabditis elegans 57643 R-CEL-1483186 https://reactome.org/PathwayBrowser/#/R-CEL-1483186 PC is converted to PS by PTDSS1 IEA Caenorhabditis elegans 57643 R-CEL-1483211 https://reactome.org/PathwayBrowser/#/R-CEL-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Caenorhabditis elegans 57643 R-CEL-1483219 https://reactome.org/PathwayBrowser/#/R-CEL-1483219 PC is exchanged with PI by PITPNB IEA Caenorhabditis elegans 57643 R-CEL-1602399 https://reactome.org/PathwayBrowser/#/R-CEL-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Caenorhabditis elegans 57643 R-CEL-1602417 https://reactome.org/PathwayBrowser/#/R-CEL-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Caenorhabditis elegans 57643 R-CEL-2029471 https://reactome.org/PathwayBrowser/#/R-CEL-2029471 Hydrolysis of PC to PA by PLD IEA Caenorhabditis elegans 57643 R-CEL-2029475 https://reactome.org/PathwayBrowser/#/R-CEL-2029475 Production of AA by iPLA2 upon FCGR activation IEA Caenorhabditis elegans 57643 R-CEL-264695 https://reactome.org/PathwayBrowser/#/R-CEL-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Caenorhabditis elegans 57643 R-CEL-429786 https://reactome.org/PathwayBrowser/#/R-CEL-429786 SGMS2 transfers phosphocholine onto ceramide IEA Caenorhabditis elegans 57643 R-CEL-429798 https://reactome.org/PathwayBrowser/#/R-CEL-429798 SGMS1 transfers phosphocholine onto ceramide IEA Caenorhabditis elegans 57643 R-CEL-5683714 https://reactome.org/PathwayBrowser/#/R-CEL-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Caenorhabditis elegans 57643 R-CEL-8848484 https://reactome.org/PathwayBrowser/#/R-CEL-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Caenorhabditis elegans 57643 R-CEL-8877153 https://reactome.org/PathwayBrowser/#/R-CEL-8877153 STARD7 binds PC IEA Caenorhabditis elegans 57643 R-CFA-111881 https://reactome.org/PathwayBrowser/#/R-CFA-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Canis familiaris 57643 R-CFA-111883 https://reactome.org/PathwayBrowser/#/R-CFA-111883 Hydrolysis of phosphatidylcholine IEA Canis familiaris 57643 R-CFA-1482533 https://reactome.org/PathwayBrowser/#/R-CFA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Canis familiaris 57643 R-CFA-1482547 https://reactome.org/PathwayBrowser/#/R-CFA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Canis familiaris 57643 R-CFA-1482781 https://reactome.org/PathwayBrowser/#/R-CFA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Canis familiaris 57643 R-CFA-1482794 https://reactome.org/PathwayBrowser/#/R-CFA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Canis familiaris 57643 R-CFA-1482816 https://reactome.org/PathwayBrowser/#/R-CFA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Canis familiaris 57643 R-CFA-1482856 https://reactome.org/PathwayBrowser/#/R-CFA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Canis familiaris 57643 R-CFA-1482862 https://reactome.org/PathwayBrowser/#/R-CFA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Canis familiaris 57643 R-CFA-1482961 https://reactome.org/PathwayBrowser/#/R-CFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Canis familiaris 57643 R-CFA-1482973 https://reactome.org/PathwayBrowser/#/R-CFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Canis familiaris 57643 R-CFA-1483087 https://reactome.org/PathwayBrowser/#/R-CFA-1483087 PI is exchanged with PC by PITPNB IEA Canis familiaris 57643 R-CFA-1483174 https://reactome.org/PathwayBrowser/#/R-CFA-1483174 PE is methylated to PC by PEMT IEA Canis familiaris 57643 R-CFA-1483182 https://reactome.org/PathwayBrowser/#/R-CFA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Canis familiaris 57643 R-CFA-1483186 https://reactome.org/PathwayBrowser/#/R-CFA-1483186 PC is converted to PS by PTDSS1 IEA Canis familiaris 57643 R-CFA-1483211 https://reactome.org/PathwayBrowser/#/R-CFA-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Canis familiaris 57643 R-CFA-1483219 https://reactome.org/PathwayBrowser/#/R-CFA-1483219 PC is exchanged with PI by PITPNB IEA Canis familiaris 57643 R-CFA-1602399 https://reactome.org/PathwayBrowser/#/R-CFA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Canis familiaris 57643 R-CFA-1602417 https://reactome.org/PathwayBrowser/#/R-CFA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Canis familiaris 57643 R-CFA-2029471 https://reactome.org/PathwayBrowser/#/R-CFA-2029471 Hydrolysis of PC to PA by PLD IEA Canis familiaris 57643 R-CFA-2029475 https://reactome.org/PathwayBrowser/#/R-CFA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Canis familiaris 57643 R-CFA-382553 https://reactome.org/PathwayBrowser/#/R-CFA-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Canis familiaris 57643 R-CFA-429786 https://reactome.org/PathwayBrowser/#/R-CFA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Canis familiaris 57643 R-CFA-429798 https://reactome.org/PathwayBrowser/#/R-CFA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Canis familiaris 57643 R-CFA-5678706 https://reactome.org/PathwayBrowser/#/R-CFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Canis familiaris 57643 R-CFA-5683714 https://reactome.org/PathwayBrowser/#/R-CFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Canis familiaris 57643 R-CFA-5684862 https://reactome.org/PathwayBrowser/#/R-CFA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Canis familiaris 57643 R-CFA-8848484 https://reactome.org/PathwayBrowser/#/R-CFA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Canis familiaris 57643 R-CFA-8849345 https://reactome.org/PathwayBrowser/#/R-CFA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Canis familiaris 57643 R-CFA-8858298 https://reactome.org/PathwayBrowser/#/R-CFA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Canis familiaris 57643 R-CFA-8873794 https://reactome.org/PathwayBrowser/#/R-CFA-8873794 PCTP binds PC IEA Canis familiaris 57643 R-CFA-8873834 https://reactome.org/PathwayBrowser/#/R-CFA-8873834 STARD10 transports PC from ER membrane to lamellar body membrane IEA Canis familiaris 57643 R-CFA-8873923 https://reactome.org/PathwayBrowser/#/R-CFA-8873923 STARD10 binds LPCAT1 and PC IEA Canis familiaris 57643 R-CFA-8877153 https://reactome.org/PathwayBrowser/#/R-CFA-8877153 STARD7 binds PC IEA Canis familiaris 57643 R-DDI-1482533 https://reactome.org/PathwayBrowser/#/R-DDI-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Dictyostelium discoideum 57643 R-DDI-1482547 https://reactome.org/PathwayBrowser/#/R-DDI-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Dictyostelium discoideum 57643 R-DDI-1482781 https://reactome.org/PathwayBrowser/#/R-DDI-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 57643 R-DDI-1482794 https://reactome.org/PathwayBrowser/#/R-DDI-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 57643 R-DDI-1482816 https://reactome.org/PathwayBrowser/#/R-DDI-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Dictyostelium discoideum 57643 R-DDI-1482856 https://reactome.org/PathwayBrowser/#/R-DDI-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Dictyostelium discoideum 57643 R-DDI-1482961 https://reactome.org/PathwayBrowser/#/R-DDI-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Dictyostelium discoideum 57643 R-DDI-1482973 https://reactome.org/PathwayBrowser/#/R-DDI-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Dictyostelium discoideum 57643 R-DDI-1483087 https://reactome.org/PathwayBrowser/#/R-DDI-1483087 PI is exchanged with PC by PITPNB IEA Dictyostelium discoideum 57643 R-DDI-1483174 https://reactome.org/PathwayBrowser/#/R-DDI-1483174 PE is methylated to PC by PEMT IEA Dictyostelium discoideum 57643 R-DDI-1483182 https://reactome.org/PathwayBrowser/#/R-DDI-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Dictyostelium discoideum 57643 R-DDI-1483186 https://reactome.org/PathwayBrowser/#/R-DDI-1483186 PC is converted to PS by PTDSS1 IEA Dictyostelium discoideum 57643 R-DDI-1483211 https://reactome.org/PathwayBrowser/#/R-DDI-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Dictyostelium discoideum 57643 R-DDI-1483219 https://reactome.org/PathwayBrowser/#/R-DDI-1483219 PC is exchanged with PI by PITPNB IEA Dictyostelium discoideum 57643 R-DDI-2029471 https://reactome.org/PathwayBrowser/#/R-DDI-2029471 Hydrolysis of PC to PA by PLD IEA Dictyostelium discoideum 57643 R-DDI-5678706 https://reactome.org/PathwayBrowser/#/R-DDI-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Dictyostelium discoideum 57643 R-DDI-5683714 https://reactome.org/PathwayBrowser/#/R-DDI-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Dictyostelium discoideum 57643 R-DME-1482533 https://reactome.org/PathwayBrowser/#/R-DME-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Drosophila melanogaster 57643 R-DME-1482547 https://reactome.org/PathwayBrowser/#/R-DME-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Drosophila melanogaster 57643 R-DME-1482781 https://reactome.org/PathwayBrowser/#/R-DME-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Drosophila melanogaster 57643 R-DME-1482794 https://reactome.org/PathwayBrowser/#/R-DME-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Drosophila melanogaster 57643 R-DME-1482816 https://reactome.org/PathwayBrowser/#/R-DME-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Drosophila melanogaster 57643 R-DME-1482856 https://reactome.org/PathwayBrowser/#/R-DME-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Drosophila melanogaster 57643 R-DME-1482961 https://reactome.org/PathwayBrowser/#/R-DME-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Drosophila melanogaster 57643 R-DME-1482973 https://reactome.org/PathwayBrowser/#/R-DME-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Drosophila melanogaster 57643 R-DME-1483087 https://reactome.org/PathwayBrowser/#/R-DME-1483087 PI is exchanged with PC by PITPNB IEA Drosophila melanogaster 57643 R-DME-1483182 https://reactome.org/PathwayBrowser/#/R-DME-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Drosophila melanogaster 57643 R-DME-1483186 https://reactome.org/PathwayBrowser/#/R-DME-1483186 PC is converted to PS by PTDSS1 IEA Drosophila melanogaster 57643 R-DME-1483211 https://reactome.org/PathwayBrowser/#/R-DME-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Drosophila melanogaster 57643 R-DME-1483219 https://reactome.org/PathwayBrowser/#/R-DME-1483219 PC is exchanged with PI by PITPNB IEA Drosophila melanogaster 57643 R-DME-1602399 https://reactome.org/PathwayBrowser/#/R-DME-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Drosophila melanogaster 57643 R-DME-1602417 https://reactome.org/PathwayBrowser/#/R-DME-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Drosophila melanogaster 57643 R-DME-2029471 https://reactome.org/PathwayBrowser/#/R-DME-2029471 Hydrolysis of PC to PA by PLD IEA Drosophila melanogaster 57643 R-DME-2029475 https://reactome.org/PathwayBrowser/#/R-DME-2029475 Production of AA by iPLA2 upon FCGR activation IEA Drosophila melanogaster 57643 R-DME-264695 https://reactome.org/PathwayBrowser/#/R-DME-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Drosophila melanogaster 57643 R-DME-5683714 https://reactome.org/PathwayBrowser/#/R-DME-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Drosophila melanogaster 57643 R-DME-8848484 https://reactome.org/PathwayBrowser/#/R-DME-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Drosophila melanogaster 57643 R-DME-8849345 https://reactome.org/PathwayBrowser/#/R-DME-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Drosophila melanogaster 57643 R-DME-8877153 https://reactome.org/PathwayBrowser/#/R-DME-8877153 STARD7 binds PC IEA Drosophila melanogaster 57643 R-DRE-111881 https://reactome.org/PathwayBrowser/#/R-DRE-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Danio rerio 57643 R-DRE-111883 https://reactome.org/PathwayBrowser/#/R-DRE-111883 Hydrolysis of phosphatidylcholine IEA Danio rerio 57643 R-DRE-1482533 https://reactome.org/PathwayBrowser/#/R-DRE-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Danio rerio 57643 R-DRE-1482547 https://reactome.org/PathwayBrowser/#/R-DRE-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Danio rerio 57643 R-DRE-1482781 https://reactome.org/PathwayBrowser/#/R-DRE-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Danio rerio 57643 R-DRE-1482794 https://reactome.org/PathwayBrowser/#/R-DRE-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Danio rerio 57643 R-DRE-1482816 https://reactome.org/PathwayBrowser/#/R-DRE-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Danio rerio 57643 R-DRE-1482827 https://reactome.org/PathwayBrowser/#/R-DRE-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Danio rerio 57643 R-DRE-1482856 https://reactome.org/PathwayBrowser/#/R-DRE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Danio rerio 57643 R-DRE-1482862 https://reactome.org/PathwayBrowser/#/R-DRE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Danio rerio 57643 R-DRE-1482961 https://reactome.org/PathwayBrowser/#/R-DRE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Danio rerio 57643 R-DRE-1482973 https://reactome.org/PathwayBrowser/#/R-DRE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Danio rerio 57643 R-DRE-1483174 https://reactome.org/PathwayBrowser/#/R-DRE-1483174 PE is methylated to PC by PEMT IEA Danio rerio 57643 R-DRE-1483186 https://reactome.org/PathwayBrowser/#/R-DRE-1483186 PC is converted to PS by PTDSS1 IEA Danio rerio 57643 R-DRE-1602417 https://reactome.org/PathwayBrowser/#/R-DRE-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Danio rerio 57643 R-DRE-429786 https://reactome.org/PathwayBrowser/#/R-DRE-429786 SGMS2 transfers phosphocholine onto ceramide IEA Danio rerio 57643 R-DRE-429798 https://reactome.org/PathwayBrowser/#/R-DRE-429798 SGMS1 transfers phosphocholine onto ceramide IEA Danio rerio 57643 R-DRE-8848484 https://reactome.org/PathwayBrowser/#/R-DRE-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Danio rerio 57643 R-DRE-8849345 https://reactome.org/PathwayBrowser/#/R-DRE-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Danio rerio 57643 R-DRE-8858298 https://reactome.org/PathwayBrowser/#/R-DRE-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Danio rerio 57643 R-DRE-8873794 https://reactome.org/PathwayBrowser/#/R-DRE-8873794 PCTP binds PC IEA Danio rerio 57643 R-DRE-8873834 https://reactome.org/PathwayBrowser/#/R-DRE-8873834 STARD10 transports PC from ER membrane to lamellar body membrane IEA Danio rerio 57643 R-DRE-8873923 https://reactome.org/PathwayBrowser/#/R-DRE-8873923 STARD10 binds LPCAT1 and PC IEA Danio rerio 57643 R-GGA-111881 https://reactome.org/PathwayBrowser/#/R-GGA-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Gallus gallus 57643 R-GGA-111883 https://reactome.org/PathwayBrowser/#/R-GGA-111883 Hydrolysis of phosphatidylcholine IEA Gallus gallus 57643 R-GGA-1482533 https://reactome.org/PathwayBrowser/#/R-GGA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus 57643 R-GGA-1482547 https://reactome.org/PathwayBrowser/#/R-GGA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus 57643 R-GGA-1482781 https://reactome.org/PathwayBrowser/#/R-GGA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Gallus gallus 57643 R-GGA-1482794 https://reactome.org/PathwayBrowser/#/R-GGA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Gallus gallus 57643 R-GGA-1482816 https://reactome.org/PathwayBrowser/#/R-GGA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Gallus gallus 57643 R-GGA-1482856 https://reactome.org/PathwayBrowser/#/R-GGA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Gallus gallus 57643 R-GGA-1482862 https://reactome.org/PathwayBrowser/#/R-GGA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Gallus gallus 57643 R-GGA-1482961 https://reactome.org/PathwayBrowser/#/R-GGA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Gallus gallus 57643 R-GGA-1482973 https://reactome.org/PathwayBrowser/#/R-GGA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Gallus gallus 57643 R-GGA-1483087 https://reactome.org/PathwayBrowser/#/R-GGA-1483087 PI is exchanged with PC by PITPNB IEA Gallus gallus 57643 R-GGA-1483174 https://reactome.org/PathwayBrowser/#/R-GGA-1483174 PE is methylated to PC by PEMT IEA Gallus gallus 57643 R-GGA-1483182 https://reactome.org/PathwayBrowser/#/R-GGA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Gallus gallus 57643 R-GGA-1483186 https://reactome.org/PathwayBrowser/#/R-GGA-1483186 PC is converted to PS by PTDSS1 IEA Gallus gallus 57643 R-GGA-1483211 https://reactome.org/PathwayBrowser/#/R-GGA-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Gallus gallus 57643 R-GGA-1483219 https://reactome.org/PathwayBrowser/#/R-GGA-1483219 PC is exchanged with PI by PITPNB IEA Gallus gallus 57643 R-GGA-1602399 https://reactome.org/PathwayBrowser/#/R-GGA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Gallus gallus 57643 R-GGA-1602417 https://reactome.org/PathwayBrowser/#/R-GGA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Gallus gallus 57643 R-GGA-2029475 https://reactome.org/PathwayBrowser/#/R-GGA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Gallus gallus 57643 R-GGA-264695 https://reactome.org/PathwayBrowser/#/R-GGA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Gallus gallus 57643 R-GGA-429786 https://reactome.org/PathwayBrowser/#/R-GGA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Gallus gallus 57643 R-GGA-429798 https://reactome.org/PathwayBrowser/#/R-GGA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Gallus gallus 57643 R-GGA-5678706 https://reactome.org/PathwayBrowser/#/R-GGA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Gallus gallus 57643 R-GGA-5683714 https://reactome.org/PathwayBrowser/#/R-GGA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Gallus gallus 57643 R-GGA-5684862 https://reactome.org/PathwayBrowser/#/R-GGA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Gallus gallus 57643 R-GGA-8848484 https://reactome.org/PathwayBrowser/#/R-GGA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Gallus gallus 57643 R-GGA-8849345 https://reactome.org/PathwayBrowser/#/R-GGA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Gallus gallus 57643 R-GGA-8873794 https://reactome.org/PathwayBrowser/#/R-GGA-8873794 PCTP binds PC IEA Gallus gallus 57643 R-GGA-8873834 https://reactome.org/PathwayBrowser/#/R-GGA-8873834 STARD10 transports PC from ER membrane to lamellar body membrane IEA Gallus gallus 57643 R-GGA-8873923 https://reactome.org/PathwayBrowser/#/R-GGA-8873923 STARD10 binds LPCAT1 and PC IEA Gallus gallus 57643 R-HSA-111881 https://reactome.org/PathwayBrowser/#/R-HSA-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase TAS Homo sapiens 57643 R-HSA-111883 https://reactome.org/PathwayBrowser/#/R-HSA-111883 Hydrolysis of phosphatidylcholine TAS Homo sapiens 57643 R-HSA-1482533 https://reactome.org/PathwayBrowser/#/R-HSA-1482533 2-acyl LPC is acylated to PC by LPCAT TAS Homo sapiens 57643 R-HSA-1482547 https://reactome.org/PathwayBrowser/#/R-HSA-1482547 1-acyl LPC is acylated to PC by LPCAT TAS Homo sapiens 57643 R-HSA-1482781 https://reactome.org/PathwayBrowser/#/R-HSA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) TAS Homo sapiens 57643 R-HSA-1482794 https://reactome.org/PathwayBrowser/#/R-HSA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) TAS Homo sapiens 57643 R-HSA-1482816 https://reactome.org/PathwayBrowser/#/R-HSA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] TAS Homo sapiens 57643 R-HSA-1482827 https://reactome.org/PathwayBrowser/#/R-HSA-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C TAS Homo sapiens 57643 R-HSA-1482856 https://reactome.org/PathwayBrowser/#/R-HSA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] TAS Homo sapiens 57643 R-HSA-1482862 https://reactome.org/PathwayBrowser/#/R-HSA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] TAS Homo sapiens 57643 R-HSA-1482961 https://reactome.org/PathwayBrowser/#/R-HSA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane TAS Homo sapiens 57643 R-HSA-1482973 https://reactome.org/PathwayBrowser/#/R-HSA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane TAS Homo sapiens 57643 R-HSA-1483087 https://reactome.org/PathwayBrowser/#/R-HSA-1483087 PI is exchanged with PC by PITPNB TAS Homo sapiens 57643 R-HSA-1483142 https://reactome.org/PathwayBrowser/#/R-HSA-1483142 PC is transphosphatidylated to PG by PLD1-4/6 IEA Homo sapiens 57643 R-HSA-1483174 https://reactome.org/PathwayBrowser/#/R-HSA-1483174 PE is methylated to PC by PEMT TAS Homo sapiens 57643 R-HSA-1483182 https://reactome.org/PathwayBrowser/#/R-HSA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 TAS Homo sapiens 57643 R-HSA-1483186 https://reactome.org/PathwayBrowser/#/R-HSA-1483186 PC is converted to PS by PTDSS1 TAS Homo sapiens 57643 R-HSA-1483211 https://reactome.org/PathwayBrowser/#/R-HSA-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane TAS Homo sapiens 57643 R-HSA-1483219 https://reactome.org/PathwayBrowser/#/R-HSA-1483219 PC is exchanged with PI by PITPNB TAS Homo sapiens 57643 R-HSA-1602399 https://reactome.org/PathwayBrowser/#/R-HSA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 TAS Homo sapiens 57643 R-HSA-1602417 https://reactome.org/PathwayBrowser/#/R-HSA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] TAS Homo sapiens 57643 R-HSA-2029471 https://reactome.org/PathwayBrowser/#/R-HSA-2029471 Hydrolysis of PC to PA by PLD TAS Homo sapiens 57643 R-HSA-2029475 https://reactome.org/PathwayBrowser/#/R-HSA-2029475 Production of AA by iPLA2 upon FCGR activation TAS Homo sapiens 57643 R-HSA-264695 https://reactome.org/PathwayBrowser/#/R-HSA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) TAS Homo sapiens 57643 R-HSA-382553 https://reactome.org/PathwayBrowser/#/R-HSA-382553 ABCA7:Apo1A-mediated phospholipid efflux TAS Homo sapiens 57643 R-HSA-429786 https://reactome.org/PathwayBrowser/#/R-HSA-429786 SGMS2 transfers phosphocholine onto ceramide TAS Homo sapiens 57643 R-HSA-429798 https://reactome.org/PathwayBrowser/#/R-HSA-429798 SGMS1 transfers phosphocholine onto ceramide TAS Homo sapiens 57643 R-HSA-5678706 https://reactome.org/PathwayBrowser/#/R-HSA-5678706 ABCB4 transports PC from plasma membrane to extracellular region TAS Homo sapiens 57643 R-HSA-5678749 https://reactome.org/PathwayBrowser/#/R-HSA-5678749 Defective ABCB4 does not transport PC from plasma membrane to extracellular region TAS Homo sapiens 57643 R-HSA-5683672 https://reactome.org/PathwayBrowser/#/R-HSA-5683672 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body TAS Homo sapiens 57643 R-HSA-5683714 https://reactome.org/PathwayBrowser/#/R-HSA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body TAS Homo sapiens 57643 R-HSA-5684862 https://reactome.org/PathwayBrowser/#/R-HSA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. TAS Homo sapiens 57643 R-HSA-5688397 https://reactome.org/PathwayBrowser/#/R-HSA-5688397 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body TAS Homo sapiens 57643 R-HSA-8848484 https://reactome.org/PathwayBrowser/#/R-HSA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane TAS Homo sapiens 57643 R-HSA-8849345 https://reactome.org/PathwayBrowser/#/R-HSA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine TAS Homo sapiens 57643 R-HSA-8858298 https://reactome.org/PathwayBrowser/#/R-HSA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE TAS Homo sapiens 57643 R-HSA-8873794 https://reactome.org/PathwayBrowser/#/R-HSA-8873794 PCTP binds PC TAS Homo sapiens 57643 R-HSA-8873830 https://reactome.org/PathwayBrowser/#/R-HSA-8873830 STARD7 transports PC from ER membrane to mitochondrial outer membrane IEA Homo sapiens 57643 R-HSA-8873834 https://reactome.org/PathwayBrowser/#/R-HSA-8873834 STARD10 transports PC from ER membrane to lamellar body membrane TAS Homo sapiens 57643 R-HSA-8873923 https://reactome.org/PathwayBrowser/#/R-HSA-8873923 STARD10 binds LPCAT1 and PC TAS Homo sapiens 57643 R-HSA-8877153 https://reactome.org/PathwayBrowser/#/R-HSA-8877153 STARD7 binds PC TAS Homo sapiens 57643 R-HSA-9680388 https://reactome.org/PathwayBrowser/#/R-HSA-9680388 CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine IEA Homo sapiens 57643 R-MMU-111881 https://reactome.org/PathwayBrowser/#/R-MMU-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Mus musculus 57643 R-MMU-111883 https://reactome.org/PathwayBrowser/#/R-MMU-111883 Hydrolysis of phosphatidylcholine IEA Mus musculus 57643 R-MMU-1482533 https://reactome.org/PathwayBrowser/#/R-MMU-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Mus musculus 57643 R-MMU-1482547 https://reactome.org/PathwayBrowser/#/R-MMU-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Mus musculus 57643 R-MMU-1482781 https://reactome.org/PathwayBrowser/#/R-MMU-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Mus musculus 57643 R-MMU-1482794 https://reactome.org/PathwayBrowser/#/R-MMU-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Mus musculus 57643 R-MMU-1482816 https://reactome.org/PathwayBrowser/#/R-MMU-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Mus musculus 57643 R-MMU-1482827 https://reactome.org/PathwayBrowser/#/R-MMU-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Mus musculus 57643 R-MMU-1482856 https://reactome.org/PathwayBrowser/#/R-MMU-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Mus musculus 57643 R-MMU-1482862 https://reactome.org/PathwayBrowser/#/R-MMU-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Mus musculus 57643 R-MMU-1482961 https://reactome.org/PathwayBrowser/#/R-MMU-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Mus musculus 57643 R-MMU-1482973 https://reactome.org/PathwayBrowser/#/R-MMU-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Mus musculus 57643 R-MMU-1483087 https://reactome.org/PathwayBrowser/#/R-MMU-1483087 PI is exchanged with PC by PITPNB IEA Mus musculus 57643 R-MMU-1483172 https://reactome.org/PathwayBrowser/#/R-MMU-1483172 PC is transphosphatidylated to PG by Pld1-4/6 TAS Mus musculus 57643 R-MMU-1483174 https://reactome.org/PathwayBrowser/#/R-MMU-1483174 PE is methylated to PC by PEMT IEA Mus musculus 57643 R-MMU-1483182 https://reactome.org/PathwayBrowser/#/R-MMU-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Mus musculus 57643 R-MMU-1483186 https://reactome.org/PathwayBrowser/#/R-MMU-1483186 PC is converted to PS by PTDSS1 IEA Mus musculus 57643 R-MMU-1483211 https://reactome.org/PathwayBrowser/#/R-MMU-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Mus musculus 57643 R-MMU-1483219 https://reactome.org/PathwayBrowser/#/R-MMU-1483219 PC is exchanged with PI by PITPNB IEA Mus musculus 57643 R-MMU-1602399 https://reactome.org/PathwayBrowser/#/R-MMU-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Mus musculus 57643 R-MMU-1602417 https://reactome.org/PathwayBrowser/#/R-MMU-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Mus musculus 57643 R-MMU-2029471 https://reactome.org/PathwayBrowser/#/R-MMU-2029471 Hydrolysis of PC to PA by PLD IEA Mus musculus 57643 R-MMU-2029475 https://reactome.org/PathwayBrowser/#/R-MMU-2029475 Production of AA by iPLA2 upon FCGR activation IEA Mus musculus 57643 R-MMU-264695 https://reactome.org/PathwayBrowser/#/R-MMU-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Mus musculus 57643 R-MMU-382553 https://reactome.org/PathwayBrowser/#/R-MMU-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Mus musculus 57643 R-MMU-429786 https://reactome.org/PathwayBrowser/#/R-MMU-429786 SGMS2 transfers phosphocholine onto ceramide IEA Mus musculus 57643 R-MMU-429798 https://reactome.org/PathwayBrowser/#/R-MMU-429798 SGMS1 transfers phosphocholine onto ceramide IEA Mus musculus 57643 R-MMU-5678706 https://reactome.org/PathwayBrowser/#/R-MMU-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Mus musculus 57643 R-MMU-5683714 https://reactome.org/PathwayBrowser/#/R-MMU-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Mus musculus 57643 R-MMU-5684862 https://reactome.org/PathwayBrowser/#/R-MMU-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Mus musculus 57643 R-MMU-8848484 https://reactome.org/PathwayBrowser/#/R-MMU-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Mus musculus 57643 R-MMU-8849345 https://reactome.org/PathwayBrowser/#/R-MMU-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Mus musculus 57643 R-MMU-8858298 https://reactome.org/PathwayBrowser/#/R-MMU-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Mus musculus 57643 R-MMU-8873794 https://reactome.org/PathwayBrowser/#/R-MMU-8873794 PCTP binds PC IEA Mus musculus 57643 R-MMU-8873834 https://reactome.org/PathwayBrowser/#/R-MMU-8873834 STARD10 transports PC from ER membrane to lamellar body membrane IEA Mus musculus 57643 R-MMU-8873923 https://reactome.org/PathwayBrowser/#/R-MMU-8873923 STARD10 binds LPCAT1 and PC IEA Mus musculus 57643 R-MMU-8877153 https://reactome.org/PathwayBrowser/#/R-MMU-8877153 STARD7 binds PC IEA Mus musculus 57643 R-MMU-9682158 https://reactome.org/PathwayBrowser/#/R-MMU-9682158 Csf1r-associated Plcg2 hydrolyzes phosphatidylcholine yielding choline phosphate and 1,2-diacylglycerol TAS Mus musculus 57643 R-PFA-1482533 https://reactome.org/PathwayBrowser/#/R-PFA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Plasmodium falciparum 57643 R-PFA-1482547 https://reactome.org/PathwayBrowser/#/R-PFA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Plasmodium falciparum 57643 R-PFA-1482961 https://reactome.org/PathwayBrowser/#/R-PFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Plasmodium falciparum 57643 R-PFA-1482973 https://reactome.org/PathwayBrowser/#/R-PFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Plasmodium falciparum 57643 R-PFA-1483087 https://reactome.org/PathwayBrowser/#/R-PFA-1483087 PI is exchanged with PC by PITPNB IEA Plasmodium falciparum 57643 R-PFA-1483186 https://reactome.org/PathwayBrowser/#/R-PFA-1483186 PC is converted to PS by PTDSS1 IEA Plasmodium falciparum 57643 R-PFA-1483211 https://reactome.org/PathwayBrowser/#/R-PFA-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Plasmodium falciparum 57643 R-PFA-1483219 https://reactome.org/PathwayBrowser/#/R-PFA-1483219 PC is exchanged with PI by PITPNB IEA Plasmodium falciparum 57643 R-PFA-429786 https://reactome.org/PathwayBrowser/#/R-PFA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Plasmodium falciparum 57643 R-PFA-429798 https://reactome.org/PathwayBrowser/#/R-PFA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Plasmodium falciparum 57643 R-PFA-5678706 https://reactome.org/PathwayBrowser/#/R-PFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Plasmodium falciparum 57643 R-PFA-5683714 https://reactome.org/PathwayBrowser/#/R-PFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Plasmodium falciparum 57643 R-RNO-111881 https://reactome.org/PathwayBrowser/#/R-RNO-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Rattus norvegicus 57643 R-RNO-111883 https://reactome.org/PathwayBrowser/#/R-RNO-111883 Hydrolysis of phosphatidylcholine IEA Rattus norvegicus 57643 R-RNO-1482533 https://reactome.org/PathwayBrowser/#/R-RNO-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Rattus norvegicus 57643 R-RNO-1482547 https://reactome.org/PathwayBrowser/#/R-RNO-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Rattus norvegicus 57643 R-RNO-1482781 https://reactome.org/PathwayBrowser/#/R-RNO-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Rattus norvegicus 57643 R-RNO-1482794 https://reactome.org/PathwayBrowser/#/R-RNO-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Rattus norvegicus 57643 R-RNO-1482816 https://reactome.org/PathwayBrowser/#/R-RNO-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Rattus norvegicus 57643 R-RNO-1482827 https://reactome.org/PathwayBrowser/#/R-RNO-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Rattus norvegicus 57643 R-RNO-1482856 https://reactome.org/PathwayBrowser/#/R-RNO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Rattus norvegicus 57643 R-RNO-1482862 https://reactome.org/PathwayBrowser/#/R-RNO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Rattus norvegicus 57643 R-RNO-1482961 https://reactome.org/PathwayBrowser/#/R-RNO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Rattus norvegicus 57643 R-RNO-1482973 https://reactome.org/PathwayBrowser/#/R-RNO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Rattus norvegicus 57643 R-RNO-1483087 https://reactome.org/PathwayBrowser/#/R-RNO-1483087 PI is exchanged with PC by PITPNB IEA Rattus norvegicus 57643 R-RNO-1483174 https://reactome.org/PathwayBrowser/#/R-RNO-1483174 PE is methylated to PC by PEMT IEA Rattus norvegicus 57643 R-RNO-1483182 https://reactome.org/PathwayBrowser/#/R-RNO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Rattus norvegicus 57643 R-RNO-1483186 https://reactome.org/PathwayBrowser/#/R-RNO-1483186 PC is converted to PS by PTDSS1 IEA Rattus norvegicus 57643 R-RNO-1483211 https://reactome.org/PathwayBrowser/#/R-RNO-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Rattus norvegicus 57643 R-RNO-1483219 https://reactome.org/PathwayBrowser/#/R-RNO-1483219 PC is exchanged with PI by PITPNB IEA Rattus norvegicus 57643 R-RNO-1602399 https://reactome.org/PathwayBrowser/#/R-RNO-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Rattus norvegicus 57643 R-RNO-1602417 https://reactome.org/PathwayBrowser/#/R-RNO-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Rattus norvegicus 57643 R-RNO-2029471 https://reactome.org/PathwayBrowser/#/R-RNO-2029471 Hydrolysis of PC to PA by PLD IEA Rattus norvegicus 57643 R-RNO-2029475 https://reactome.org/PathwayBrowser/#/R-RNO-2029475 Production of AA by iPLA2 upon FCGR activation IEA Rattus norvegicus 57643 R-RNO-264695 https://reactome.org/PathwayBrowser/#/R-RNO-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Rattus norvegicus 57643 R-RNO-382553 https://reactome.org/PathwayBrowser/#/R-RNO-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Rattus norvegicus 57643 R-RNO-429786 https://reactome.org/PathwayBrowser/#/R-RNO-429786 SGMS2 transfers phosphocholine onto ceramide IEA Rattus norvegicus 57643 R-RNO-429798 https://reactome.org/PathwayBrowser/#/R-RNO-429798 SGMS1 transfers phosphocholine onto ceramide IEA Rattus norvegicus 57643 R-RNO-5678706 https://reactome.org/PathwayBrowser/#/R-RNO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Rattus norvegicus 57643 R-RNO-5683714 https://reactome.org/PathwayBrowser/#/R-RNO-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Rattus norvegicus 57643 R-RNO-5684862 https://reactome.org/PathwayBrowser/#/R-RNO-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Rattus norvegicus 57643 R-RNO-8848484 https://reactome.org/PathwayBrowser/#/R-RNO-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Rattus norvegicus 57643 R-RNO-8849345 https://reactome.org/PathwayBrowser/#/R-RNO-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Rattus norvegicus 57643 R-RNO-8858298 https://reactome.org/PathwayBrowser/#/R-RNO-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Rattus norvegicus 57643 R-RNO-8873794 https://reactome.org/PathwayBrowser/#/R-RNO-8873794 PCTP binds PC IEA Rattus norvegicus 57643 R-RNO-8873834 https://reactome.org/PathwayBrowser/#/R-RNO-8873834 STARD10 transports PC from ER membrane to lamellar body membrane IEA Rattus norvegicus 57643 R-RNO-8873889 https://reactome.org/PathwayBrowser/#/R-RNO-8873889 Stard7 transports PC from ER membrane to mitochondrial outer membrane TAS Rattus norvegicus 57643 R-RNO-8873923 https://reactome.org/PathwayBrowser/#/R-RNO-8873923 STARD10 binds LPCAT1 and PC IEA Rattus norvegicus 57643 R-RNO-8877153 https://reactome.org/PathwayBrowser/#/R-RNO-8877153 STARD7 binds PC IEA Rattus norvegicus 57643 R-SCE-111881 https://reactome.org/PathwayBrowser/#/R-SCE-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Saccharomyces cerevisiae 57643 R-SCE-111883 https://reactome.org/PathwayBrowser/#/R-SCE-111883 Hydrolysis of phosphatidylcholine IEA Saccharomyces cerevisiae 57643 R-SCE-1482533 https://reactome.org/PathwayBrowser/#/R-SCE-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Saccharomyces cerevisiae 57643 R-SCE-1482547 https://reactome.org/PathwayBrowser/#/R-SCE-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Saccharomyces cerevisiae 57643 R-SCE-1482781 https://reactome.org/PathwayBrowser/#/R-SCE-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 57643 R-SCE-1482794 https://reactome.org/PathwayBrowser/#/R-SCE-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 57643 R-SCE-1482816 https://reactome.org/PathwayBrowser/#/R-SCE-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Saccharomyces cerevisiae 57643 R-SCE-1482827 https://reactome.org/PathwayBrowser/#/R-SCE-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Saccharomyces cerevisiae 57643 R-SCE-1482856 https://reactome.org/PathwayBrowser/#/R-SCE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Saccharomyces cerevisiae 57643 R-SCE-1482862 https://reactome.org/PathwayBrowser/#/R-SCE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Saccharomyces cerevisiae 57643 R-SCE-1482961 https://reactome.org/PathwayBrowser/#/R-SCE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Saccharomyces cerevisiae 57643 R-SCE-1482973 https://reactome.org/PathwayBrowser/#/R-SCE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Saccharomyces cerevisiae 57643 R-SCE-1483174 https://reactome.org/PathwayBrowser/#/R-SCE-1483174 PE is methylated to PC by PEMT IEA Saccharomyces cerevisiae 57643 R-SCE-1483182 https://reactome.org/PathwayBrowser/#/R-SCE-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Saccharomyces cerevisiae 57643 R-SCE-2029471 https://reactome.org/PathwayBrowser/#/R-SCE-2029471 Hydrolysis of PC to PA by PLD IEA Saccharomyces cerevisiae 57643 R-SCE-264695 https://reactome.org/PathwayBrowser/#/R-SCE-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Saccharomyces cerevisiae 57643 R-SCE-8848484 https://reactome.org/PathwayBrowser/#/R-SCE-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Saccharomyces cerevisiae 57643 R-SCE-8849345 https://reactome.org/PathwayBrowser/#/R-SCE-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Saccharomyces cerevisiae 57643 R-SPO-111881 https://reactome.org/PathwayBrowser/#/R-SPO-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Schizosaccharomyces pombe 57643 R-SPO-111883 https://reactome.org/PathwayBrowser/#/R-SPO-111883 Hydrolysis of phosphatidylcholine IEA Schizosaccharomyces pombe 57643 R-SPO-1482533 https://reactome.org/PathwayBrowser/#/R-SPO-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Schizosaccharomyces pombe 57643 R-SPO-1482547 https://reactome.org/PathwayBrowser/#/R-SPO-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Schizosaccharomyces pombe 57643 R-SPO-1482816 https://reactome.org/PathwayBrowser/#/R-SPO-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Schizosaccharomyces pombe 57643 R-SPO-1482827 https://reactome.org/PathwayBrowser/#/R-SPO-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Schizosaccharomyces pombe 57643 R-SPO-1482856 https://reactome.org/PathwayBrowser/#/R-SPO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Schizosaccharomyces pombe 57643 R-SPO-1482862 https://reactome.org/PathwayBrowser/#/R-SPO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Schizosaccharomyces pombe 57643 R-SPO-1482961 https://reactome.org/PathwayBrowser/#/R-SPO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Schizosaccharomyces pombe 57643 R-SPO-1482973 https://reactome.org/PathwayBrowser/#/R-SPO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Schizosaccharomyces pombe 57643 R-SPO-1483174 https://reactome.org/PathwayBrowser/#/R-SPO-1483174 PE is methylated to PC by PEMT IEA Schizosaccharomyces pombe 57643 R-SPO-1483182 https://reactome.org/PathwayBrowser/#/R-SPO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Schizosaccharomyces pombe 57643 R-SPO-2029471 https://reactome.org/PathwayBrowser/#/R-SPO-2029471 Hydrolysis of PC to PA by PLD IEA Schizosaccharomyces pombe 57643 R-SPO-5678706 https://reactome.org/PathwayBrowser/#/R-SPO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Schizosaccharomyces pombe 57643 R-SPO-8848484 https://reactome.org/PathwayBrowser/#/R-SPO-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Schizosaccharomyces pombe 57643 R-SSC-111881 https://reactome.org/PathwayBrowser/#/R-SSC-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Sus scrofa 57643 R-SSC-111883 https://reactome.org/PathwayBrowser/#/R-SSC-111883 Hydrolysis of phosphatidylcholine IEA Sus scrofa 57643 R-SSC-1482533 https://reactome.org/PathwayBrowser/#/R-SSC-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Sus scrofa 57643 R-SSC-1482547 https://reactome.org/PathwayBrowser/#/R-SSC-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Sus scrofa 57643 R-SSC-1482781 https://reactome.org/PathwayBrowser/#/R-SSC-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Sus scrofa 57643 R-SSC-1482794 https://reactome.org/PathwayBrowser/#/R-SSC-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Sus scrofa 57643 R-SSC-1482816 https://reactome.org/PathwayBrowser/#/R-SSC-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Sus scrofa 57643 R-SSC-1482856 https://reactome.org/PathwayBrowser/#/R-SSC-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Sus scrofa 57643 R-SSC-1482862 https://reactome.org/PathwayBrowser/#/R-SSC-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Sus scrofa 57643 R-SSC-1482961 https://reactome.org/PathwayBrowser/#/R-SSC-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Sus scrofa 57643 R-SSC-1482973 https://reactome.org/PathwayBrowser/#/R-SSC-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Sus scrofa 57643 R-SSC-1483087 https://reactome.org/PathwayBrowser/#/R-SSC-1483087 PI is exchanged with PC by PITPNB IEA Sus scrofa 57643 R-SSC-1483174 https://reactome.org/PathwayBrowser/#/R-SSC-1483174 PE is methylated to PC by PEMT IEA Sus scrofa 57643 R-SSC-1483182 https://reactome.org/PathwayBrowser/#/R-SSC-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Sus scrofa 57643 R-SSC-1483186 https://reactome.org/PathwayBrowser/#/R-SSC-1483186 PC is converted to PS by PTDSS1 IEA Sus scrofa 57643 R-SSC-1483211 https://reactome.org/PathwayBrowser/#/R-SSC-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Sus scrofa 57643 R-SSC-1483219 https://reactome.org/PathwayBrowser/#/R-SSC-1483219 PC is exchanged with PI by PITPNB IEA Sus scrofa 57643 R-SSC-1602399 https://reactome.org/PathwayBrowser/#/R-SSC-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Sus scrofa 57643 R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa 57643 R-SSC-2029471 https://reactome.org/PathwayBrowser/#/R-SSC-2029471 Hydrolysis of PC to PA by PLD IEA Sus scrofa 57643 R-SSC-2029475 https://reactome.org/PathwayBrowser/#/R-SSC-2029475 Production of AA by iPLA2 upon FCGR activation IEA Sus scrofa 57643 R-SSC-264695 https://reactome.org/PathwayBrowser/#/R-SSC-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Sus scrofa 57643 R-SSC-382553 https://reactome.org/PathwayBrowser/#/R-SSC-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Sus scrofa 57643 R-SSC-429786 https://reactome.org/PathwayBrowser/#/R-SSC-429786 SGMS2 transfers phosphocholine onto ceramide IEA Sus scrofa 57643 R-SSC-429798 https://reactome.org/PathwayBrowser/#/R-SSC-429798 SGMS1 transfers phosphocholine onto ceramide IEA Sus scrofa 57643 R-SSC-5678706 https://reactome.org/PathwayBrowser/#/R-SSC-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Sus scrofa 57643 R-SSC-5683714 https://reactome.org/PathwayBrowser/#/R-SSC-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Sus scrofa 57643 R-SSC-5684862 https://reactome.org/PathwayBrowser/#/R-SSC-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Sus scrofa 57643 R-SSC-8848484 https://reactome.org/PathwayBrowser/#/R-SSC-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Sus scrofa 57643 R-SSC-8849345 https://reactome.org/PathwayBrowser/#/R-SSC-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Sus scrofa 57643 R-SSC-8858298 https://reactome.org/PathwayBrowser/#/R-SSC-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Sus scrofa 57643 R-SSC-8873794 https://reactome.org/PathwayBrowser/#/R-SSC-8873794 PCTP binds PC IEA Sus scrofa 57643 R-SSC-8873834 https://reactome.org/PathwayBrowser/#/R-SSC-8873834 STARD10 transports PC from ER membrane to lamellar body membrane IEA Sus scrofa 57643 R-SSC-8873923 https://reactome.org/PathwayBrowser/#/R-SSC-8873923 STARD10 binds LPCAT1 and PC IEA Sus scrofa 57643 R-SSC-8877153 https://reactome.org/PathwayBrowser/#/R-SSC-8877153 STARD7 binds PC IEA Sus scrofa 57643 R-XTR-111881 https://reactome.org/PathwayBrowser/#/R-XTR-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase IEA Xenopus tropicalis 57643 R-XTR-111883 https://reactome.org/PathwayBrowser/#/R-XTR-111883 Hydrolysis of phosphatidylcholine IEA Xenopus tropicalis 57643 R-XTR-1482533 https://reactome.org/PathwayBrowser/#/R-XTR-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Xenopus tropicalis 57643 R-XTR-1482547 https://reactome.org/PathwayBrowser/#/R-XTR-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Xenopus tropicalis 57643 R-XTR-1482781 https://reactome.org/PathwayBrowser/#/R-XTR-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Xenopus tropicalis 57643 R-XTR-1482794 https://reactome.org/PathwayBrowser/#/R-XTR-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Xenopus tropicalis 57643 R-XTR-1482816 https://reactome.org/PathwayBrowser/#/R-XTR-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Xenopus tropicalis 57643 R-XTR-1482856 https://reactome.org/PathwayBrowser/#/R-XTR-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Xenopus tropicalis 57643 R-XTR-1482862 https://reactome.org/PathwayBrowser/#/R-XTR-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Xenopus tropicalis 57643 R-XTR-1482961 https://reactome.org/PathwayBrowser/#/R-XTR-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Xenopus tropicalis 57643 R-XTR-1482973 https://reactome.org/PathwayBrowser/#/R-XTR-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Xenopus tropicalis 57643 R-XTR-1483087 https://reactome.org/PathwayBrowser/#/R-XTR-1483087 PI is exchanged with PC by PITPNB IEA Xenopus tropicalis 57643 R-XTR-1483174 https://reactome.org/PathwayBrowser/#/R-XTR-1483174 PE is methylated to PC by PEMT IEA Xenopus tropicalis 57643 R-XTR-1483182 https://reactome.org/PathwayBrowser/#/R-XTR-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Xenopus tropicalis 57643 R-XTR-1483186 https://reactome.org/PathwayBrowser/#/R-XTR-1483186 PC is converted to PS by PTDSS1 IEA Xenopus tropicalis 57643 R-XTR-1483211 https://reactome.org/PathwayBrowser/#/R-XTR-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Xenopus tropicalis 57643 R-XTR-1483219 https://reactome.org/PathwayBrowser/#/R-XTR-1483219 PC is exchanged with PI by PITPNB IEA Xenopus tropicalis 57643 R-XTR-1602417 https://reactome.org/PathwayBrowser/#/R-XTR-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Xenopus tropicalis 57643 R-XTR-2029471 https://reactome.org/PathwayBrowser/#/R-XTR-2029471 Hydrolysis of PC to PA by PLD IEA Xenopus tropicalis 57643 R-XTR-2029475 https://reactome.org/PathwayBrowser/#/R-XTR-2029475 Production of AA by iPLA2 upon FCGR activation IEA Xenopus tropicalis 57643 R-XTR-264695 https://reactome.org/PathwayBrowser/#/R-XTR-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Xenopus tropicalis 57643 R-XTR-429786 https://reactome.org/PathwayBrowser/#/R-XTR-429786 SGMS2 transfers phosphocholine onto ceramide IEA Xenopus tropicalis 57643 R-XTR-429798 https://reactome.org/PathwayBrowser/#/R-XTR-429798 SGMS1 transfers phosphocholine onto ceramide IEA Xenopus tropicalis 57643 R-XTR-5683714 https://reactome.org/PathwayBrowser/#/R-XTR-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Xenopus tropicalis 57643 R-XTR-8848484 https://reactome.org/PathwayBrowser/#/R-XTR-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Xenopus tropicalis 57643 R-XTR-8849345 https://reactome.org/PathwayBrowser/#/R-XTR-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Xenopus tropicalis 57643 R-XTR-8858298 https://reactome.org/PathwayBrowser/#/R-XTR-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Xenopus tropicalis 57643 R-XTR-8873834 https://reactome.org/PathwayBrowser/#/R-XTR-8873834 STARD10 transports PC from ER membrane to lamellar body membrane IEA Xenopus tropicalis 57643 R-XTR-8873923 https://reactome.org/PathwayBrowser/#/R-XTR-8873923 STARD10 binds LPCAT1 and PC IEA Xenopus tropicalis 57643 R-XTR-8877153 https://reactome.org/PathwayBrowser/#/R-XTR-8877153 STARD7 binds PC IEA Xenopus tropicalis 57651 R-BTA-6787321 https://reactome.org/PathwayBrowser/#/R-BTA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Bos taurus 57651 R-BTA-8982667 https://reactome.org/PathwayBrowser/#/R-BTA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Bos taurus 57651 R-CEL-6787321 https://reactome.org/PathwayBrowser/#/R-CEL-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Caenorhabditis elegans 57651 R-CEL-8982667 https://reactome.org/PathwayBrowser/#/R-CEL-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Caenorhabditis elegans 57651 R-CFA-6787321 https://reactome.org/PathwayBrowser/#/R-CFA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Canis familiaris 57651 R-CFA-8982667 https://reactome.org/PathwayBrowser/#/R-CFA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Canis familiaris 57651 R-DDI-8982667 https://reactome.org/PathwayBrowser/#/R-DDI-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Dictyostelium discoideum 57651 R-DME-6787321 https://reactome.org/PathwayBrowser/#/R-DME-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Drosophila melanogaster 57651 R-DME-8982667 https://reactome.org/PathwayBrowser/#/R-DME-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Drosophila melanogaster 57651 R-DRE-6787321 https://reactome.org/PathwayBrowser/#/R-DRE-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Danio rerio 57651 R-DRE-8982667 https://reactome.org/PathwayBrowser/#/R-DRE-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Danio rerio 57651 R-GGA-6787321 https://reactome.org/PathwayBrowser/#/R-GGA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Gallus gallus 57651 R-GGA-8982667 https://reactome.org/PathwayBrowser/#/R-GGA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Gallus gallus 57651 R-HSA-6787321 https://reactome.org/PathwayBrowser/#/R-HSA-6787321 DERA cleaves dR5P to GA3P and CH3CHO TAS Homo sapiens 57651 R-HSA-8982667 https://reactome.org/PathwayBrowser/#/R-HSA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P TAS Homo sapiens 57651 R-MMU-6787321 https://reactome.org/PathwayBrowser/#/R-MMU-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Mus musculus 57651 R-MMU-8982667 https://reactome.org/PathwayBrowser/#/R-MMU-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Mus musculus 57651 R-PFA-8982667 https://reactome.org/PathwayBrowser/#/R-PFA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Plasmodium falciparum 57651 R-RNO-6787321 https://reactome.org/PathwayBrowser/#/R-RNO-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Rattus norvegicus 57651 R-RNO-8982667 https://reactome.org/PathwayBrowser/#/R-RNO-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Rattus norvegicus 57651 R-SCE-8982667 https://reactome.org/PathwayBrowser/#/R-SCE-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Saccharomyces cerevisiae 57651 R-SPO-8982667 https://reactome.org/PathwayBrowser/#/R-SPO-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Schizosaccharomyces pombe 57651 R-SSC-6787321 https://reactome.org/PathwayBrowser/#/R-SSC-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Sus scrofa 57651 R-SSC-8982667 https://reactome.org/PathwayBrowser/#/R-SSC-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Sus scrofa 57651 R-XTR-6787321 https://reactome.org/PathwayBrowser/#/R-XTR-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Xenopus tropicalis 57651 R-XTR-8982667 https://reactome.org/PathwayBrowser/#/R-XTR-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Xenopus tropicalis 57655 R-BTA-5661290 https://reactome.org/PathwayBrowser/#/R-BTA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Bos taurus 57655 R-CEL-5661290 https://reactome.org/PathwayBrowser/#/R-CEL-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Caenorhabditis elegans 57655 R-CFA-5661290 https://reactome.org/PathwayBrowser/#/R-CFA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Canis familiaris 57655 R-DME-5661290 https://reactome.org/PathwayBrowser/#/R-DME-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Drosophila melanogaster 57655 R-DRE-5661290 https://reactome.org/PathwayBrowser/#/R-DRE-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Danio rerio 57655 R-GGA-5661290 https://reactome.org/PathwayBrowser/#/R-GGA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Gallus gallus 57655 R-HSA-5661290 https://reactome.org/PathwayBrowser/#/R-HSA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate TAS Homo sapiens 57655 R-HSA-5662473 https://reactome.org/PathwayBrowser/#/R-HSA-5662473 KGPDC decarboxylates 3-dehydro-L-gulonate to L-xylulose TAS Homo sapiens 57655 R-MMU-5661290 https://reactome.org/PathwayBrowser/#/R-MMU-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Mus musculus 57655 R-RNO-5661290 https://reactome.org/PathwayBrowser/#/R-RNO-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Rattus norvegicus 57655 R-SSC-5661290 https://reactome.org/PathwayBrowser/#/R-SSC-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Sus scrofa 57655 R-XTR-5661290 https://reactome.org/PathwayBrowser/#/R-XTR-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Xenopus tropicalis 57660 R-BTA-1855159 https://reactome.org/PathwayBrowser/#/R-BTA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Bos taurus 57660 R-BTA-1855169 https://reactome.org/PathwayBrowser/#/R-BTA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Bos taurus 57660 R-BTA-1855171 https://reactome.org/PathwayBrowser/#/R-BTA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Bos taurus 57660 R-BTA-1855197 https://reactome.org/PathwayBrowser/#/R-BTA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Bos taurus 57660 R-BTA-1855228 https://reactome.org/PathwayBrowser/#/R-BTA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 57660 R-BTA-2267372 https://reactome.org/PathwayBrowser/#/R-BTA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Bos taurus 57660 R-BTA-9687638 https://reactome.org/PathwayBrowser/#/R-BTA-9687638 MLKL binds IP4, IP5 and IP6 IEA Bos taurus 57660 R-CEL-1855228 https://reactome.org/PathwayBrowser/#/R-CEL-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 57660 R-CFA-1855159 https://reactome.org/PathwayBrowser/#/R-CFA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Canis familiaris 57660 R-CFA-1855169 https://reactome.org/PathwayBrowser/#/R-CFA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 57660 R-CFA-1855171 https://reactome.org/PathwayBrowser/#/R-CFA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Canis familiaris 57660 R-CFA-1855197 https://reactome.org/PathwayBrowser/#/R-CFA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 57660 R-CFA-1855228 https://reactome.org/PathwayBrowser/#/R-CFA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 57660 R-CFA-2267372 https://reactome.org/PathwayBrowser/#/R-CFA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Canis familiaris 57660 R-DDI-1855159 https://reactome.org/PathwayBrowser/#/R-DDI-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 57660 R-DDI-1855169 https://reactome.org/PathwayBrowser/#/R-DDI-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 57660 R-DDI-1855171 https://reactome.org/PathwayBrowser/#/R-DDI-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 57660 R-DDI-1855197 https://reactome.org/PathwayBrowser/#/R-DDI-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 57660 R-DDI-1855228 https://reactome.org/PathwayBrowser/#/R-DDI-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 57660 R-DDI-2267372 https://reactome.org/PathwayBrowser/#/R-DDI-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Dictyostelium discoideum 57660 R-DME-1855228 https://reactome.org/PathwayBrowser/#/R-DME-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 57660 R-DRE-1855159 https://reactome.org/PathwayBrowser/#/R-DRE-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Danio rerio 57660 R-DRE-1855169 https://reactome.org/PathwayBrowser/#/R-DRE-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Danio rerio 57660 R-DRE-1855171 https://reactome.org/PathwayBrowser/#/R-DRE-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Danio rerio 57660 R-DRE-1855197 https://reactome.org/PathwayBrowser/#/R-DRE-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Danio rerio 57660 R-DRE-1855228 https://reactome.org/PathwayBrowser/#/R-DRE-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 57660 R-DRE-2267372 https://reactome.org/PathwayBrowser/#/R-DRE-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Danio rerio 57660 R-GGA-1855159 https://reactome.org/PathwayBrowser/#/R-GGA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Gallus gallus 57660 R-GGA-1855169 https://reactome.org/PathwayBrowser/#/R-GGA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 57660 R-GGA-1855171 https://reactome.org/PathwayBrowser/#/R-GGA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Gallus gallus 57660 R-GGA-1855197 https://reactome.org/PathwayBrowser/#/R-GGA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 57660 R-GGA-1855228 https://reactome.org/PathwayBrowser/#/R-GGA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 57660 R-GGA-2267372 https://reactome.org/PathwayBrowser/#/R-GGA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Gallus gallus 57660 R-HSA-1855159 https://reactome.org/PathwayBrowser/#/R-HSA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol TAS Homo sapiens 57660 R-HSA-1855169 https://reactome.org/PathwayBrowser/#/R-HSA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 57660 R-HSA-1855171 https://reactome.org/PathwayBrowser/#/R-HSA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol TAS Homo sapiens 57660 R-HSA-1855197 https://reactome.org/PathwayBrowser/#/R-HSA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 57660 R-HSA-1855201 https://reactome.org/PathwayBrowser/#/R-HSA-1855201 I(1,3,4,6)P4 transports from the cytosol to the nucleus TAS Homo sapiens 57660 R-HSA-1855228 https://reactome.org/PathwayBrowser/#/R-HSA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 57660 R-HSA-2267372 https://reactome.org/PathwayBrowser/#/R-HSA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 TAS Homo sapiens 57660 R-HSA-5357927 https://reactome.org/PathwayBrowser/#/R-HSA-5357927 MLKL oligomerizes TAS Homo sapiens 57660 R-HSA-9687638 https://reactome.org/PathwayBrowser/#/R-HSA-9687638 MLKL binds IP4, IP5 and IP6 TAS Homo sapiens 57660 R-MMU-1855159 https://reactome.org/PathwayBrowser/#/R-MMU-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Mus musculus 57660 R-MMU-1855169 https://reactome.org/PathwayBrowser/#/R-MMU-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Mus musculus 57660 R-MMU-1855171 https://reactome.org/PathwayBrowser/#/R-MMU-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Mus musculus 57660 R-MMU-1855197 https://reactome.org/PathwayBrowser/#/R-MMU-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Mus musculus 57660 R-MMU-1855228 https://reactome.org/PathwayBrowser/#/R-MMU-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 57660 R-MMU-2267372 https://reactome.org/PathwayBrowser/#/R-MMU-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Mus musculus 57660 R-MMU-9687638 https://reactome.org/PathwayBrowser/#/R-MMU-9687638 MLKL binds IP4, IP5 and IP6 IEA Mus musculus 57660 R-PFA-1855228 https://reactome.org/PathwayBrowser/#/R-PFA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 57660 R-RNO-1855159 https://reactome.org/PathwayBrowser/#/R-RNO-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 57660 R-RNO-1855169 https://reactome.org/PathwayBrowser/#/R-RNO-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 57660 R-RNO-1855171 https://reactome.org/PathwayBrowser/#/R-RNO-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 57660 R-RNO-1855197 https://reactome.org/PathwayBrowser/#/R-RNO-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 57660 R-RNO-1855228 https://reactome.org/PathwayBrowser/#/R-RNO-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 57660 R-RNO-2267372 https://reactome.org/PathwayBrowser/#/R-RNO-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Rattus norvegicus 57660 R-RNO-9687638 https://reactome.org/PathwayBrowser/#/R-RNO-9687638 MLKL binds IP4, IP5 and IP6 IEA Rattus norvegicus 57660 R-SSC-1855159 https://reactome.org/PathwayBrowser/#/R-SSC-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Sus scrofa 57660 R-SSC-1855169 https://reactome.org/PathwayBrowser/#/R-SSC-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 57660 R-SSC-1855171 https://reactome.org/PathwayBrowser/#/R-SSC-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Sus scrofa 57660 R-SSC-1855197 https://reactome.org/PathwayBrowser/#/R-SSC-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 57660 R-SSC-2267372 https://reactome.org/PathwayBrowser/#/R-SSC-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Sus scrofa 57660 R-SSC-9687638 https://reactome.org/PathwayBrowser/#/R-SSC-9687638 MLKL binds IP4, IP5 and IP6 IEA Sus scrofa 57660 R-XTR-1855159 https://reactome.org/PathwayBrowser/#/R-XTR-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 57660 R-XTR-1855169 https://reactome.org/PathwayBrowser/#/R-XTR-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 57660 R-XTR-1855171 https://reactome.org/PathwayBrowser/#/R-XTR-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 57660 R-XTR-1855197 https://reactome.org/PathwayBrowser/#/R-XTR-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 57660 R-XTR-1855228 https://reactome.org/PathwayBrowser/#/R-XTR-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 57660 R-XTR-2267372 https://reactome.org/PathwayBrowser/#/R-XTR-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Xenopus tropicalis 57667 R-BTA-110137 https://reactome.org/PathwayBrowser/#/R-BTA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Bos taurus 57667 R-BTA-110138 https://reactome.org/PathwayBrowser/#/R-BTA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 57667 R-BTA-110141 https://reactome.org/PathwayBrowser/#/R-BTA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Bos taurus 57667 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 57667 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 57667 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 57667 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 57667 R-BTA-6788798 https://reactome.org/PathwayBrowser/#/R-BTA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 57667 R-BTA-6788810 https://reactome.org/PathwayBrowser/#/R-BTA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 57667 R-BTA-74220 https://reactome.org/PathwayBrowser/#/R-BTA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Bos taurus 57667 R-CEL-110137 https://reactome.org/PathwayBrowser/#/R-CEL-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Caenorhabditis elegans 57667 R-CEL-110138 https://reactome.org/PathwayBrowser/#/R-CEL-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 57667 R-CEL-110141 https://reactome.org/PathwayBrowser/#/R-CEL-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Caenorhabditis elegans 57667 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 57667 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 57667 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 57667 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 57667 R-CEL-6788810 https://reactome.org/PathwayBrowser/#/R-CEL-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 57667 R-CEL-74220 https://reactome.org/PathwayBrowser/#/R-CEL-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Caenorhabditis elegans 57667 R-CFA-110137 https://reactome.org/PathwayBrowser/#/R-CFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Canis familiaris 57667 R-CFA-110138 https://reactome.org/PathwayBrowser/#/R-CFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 57667 R-CFA-110141 https://reactome.org/PathwayBrowser/#/R-CFA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Canis familiaris 57667 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 57667 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 57667 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 57667 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 57667 R-CFA-6788798 https://reactome.org/PathwayBrowser/#/R-CFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 57667 R-CFA-6788810 https://reactome.org/PathwayBrowser/#/R-CFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 57667 R-CFA-74220 https://reactome.org/PathwayBrowser/#/R-CFA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Canis familiaris 57667 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 57667 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 57667 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 57667 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 57667 R-DDI-6788798 https://reactome.org/PathwayBrowser/#/R-DDI-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 57667 R-DDI-6788810 https://reactome.org/PathwayBrowser/#/R-DDI-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 57667 R-DME-110137 https://reactome.org/PathwayBrowser/#/R-DME-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Drosophila melanogaster 57667 R-DME-110138 https://reactome.org/PathwayBrowser/#/R-DME-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 57667 R-DME-110141 https://reactome.org/PathwayBrowser/#/R-DME-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Drosophila melanogaster 57667 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 57667 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 57667 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 57667 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 57667 R-DME-6788798 https://reactome.org/PathwayBrowser/#/R-DME-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 57667 R-DME-6788810 https://reactome.org/PathwayBrowser/#/R-DME-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 57667 R-DME-74220 https://reactome.org/PathwayBrowser/#/R-DME-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Drosophila melanogaster 57667 R-DRE-110137 https://reactome.org/PathwayBrowser/#/R-DRE-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Danio rerio 57667 R-DRE-110138 https://reactome.org/PathwayBrowser/#/R-DRE-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 57667 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 57667 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 57667 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 57667 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 57667 R-DRE-6788798 https://reactome.org/PathwayBrowser/#/R-DRE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 57667 R-DRE-6788810 https://reactome.org/PathwayBrowser/#/R-DRE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 57667 R-GGA-110137 https://reactome.org/PathwayBrowser/#/R-GGA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Gallus gallus 57667 R-GGA-110138 https://reactome.org/PathwayBrowser/#/R-GGA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 57667 R-GGA-110141 https://reactome.org/PathwayBrowser/#/R-GGA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Gallus gallus 57667 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 57667 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 57667 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 57667 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 57667 R-GGA-6788798 https://reactome.org/PathwayBrowser/#/R-GGA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 57667 R-GGA-6788810 https://reactome.org/PathwayBrowser/#/R-GGA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 57667 R-GGA-74220 https://reactome.org/PathwayBrowser/#/R-GGA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Gallus gallus 57667 R-HSA-110137 https://reactome.org/PathwayBrowser/#/R-HSA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP TAS Homo sapiens 57667 R-HSA-110138 https://reactome.org/PathwayBrowser/#/R-HSA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 57667 R-HSA-110141 https://reactome.org/PathwayBrowser/#/R-HSA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) TAS Homo sapiens 57667 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 57667 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 57667 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 57667 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 57667 R-HSA-6788798 https://reactome.org/PathwayBrowser/#/R-HSA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 57667 R-HSA-6788810 https://reactome.org/PathwayBrowser/#/R-HSA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 57667 R-HSA-74220 https://reactome.org/PathwayBrowser/#/R-HSA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) TAS Homo sapiens 57667 R-MMU-110137 https://reactome.org/PathwayBrowser/#/R-MMU-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Mus musculus 57667 R-MMU-110138 https://reactome.org/PathwayBrowser/#/R-MMU-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 57667 R-MMU-110141 https://reactome.org/PathwayBrowser/#/R-MMU-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Mus musculus 57667 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 57667 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 57667 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 57667 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 57667 R-MMU-6788798 https://reactome.org/PathwayBrowser/#/R-MMU-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 57667 R-MMU-6788810 https://reactome.org/PathwayBrowser/#/R-MMU-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 57667 R-MMU-74220 https://reactome.org/PathwayBrowser/#/R-MMU-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Mus musculus 57667 R-PFA-110137 https://reactome.org/PathwayBrowser/#/R-PFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Plasmodium falciparum 57667 R-PFA-110138 https://reactome.org/PathwayBrowser/#/R-PFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 57667 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 57667 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 57667 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 57667 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 57667 R-PFA-6788798 https://reactome.org/PathwayBrowser/#/R-PFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 57667 R-PFA-6788810 https://reactome.org/PathwayBrowser/#/R-PFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 57667 R-RNO-110137 https://reactome.org/PathwayBrowser/#/R-RNO-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Rattus norvegicus 57667 R-RNO-110138 https://reactome.org/PathwayBrowser/#/R-RNO-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 57667 R-RNO-110141 https://reactome.org/PathwayBrowser/#/R-RNO-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Rattus norvegicus 57667 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 57667 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 57667 R-RNO-6788798 https://reactome.org/PathwayBrowser/#/R-RNO-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 57667 R-RNO-6788810 https://reactome.org/PathwayBrowser/#/R-RNO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 57667 R-RNO-74220 https://reactome.org/PathwayBrowser/#/R-RNO-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Rattus norvegicus 57667 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 57667 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 57667 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 57667 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 57667 R-SCE-6788798 https://reactome.org/PathwayBrowser/#/R-SCE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 57667 R-SCE-6788810 https://reactome.org/PathwayBrowser/#/R-SCE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 57667 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 57667 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 57667 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 57667 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 57667 R-SPO-6788810 https://reactome.org/PathwayBrowser/#/R-SPO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Schizosaccharomyces pombe 57667 R-SSC-110137 https://reactome.org/PathwayBrowser/#/R-SSC-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Sus scrofa 57667 R-SSC-110138 https://reactome.org/PathwayBrowser/#/R-SSC-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 57667 R-SSC-110141 https://reactome.org/PathwayBrowser/#/R-SSC-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Sus scrofa 57667 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 57667 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 57667 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 57667 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 57667 R-SSC-6788798 https://reactome.org/PathwayBrowser/#/R-SSC-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 57667 R-SSC-6788810 https://reactome.org/PathwayBrowser/#/R-SSC-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 57667 R-SSC-74220 https://reactome.org/PathwayBrowser/#/R-SSC-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Sus scrofa 57667 R-XTR-110137 https://reactome.org/PathwayBrowser/#/R-XTR-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Xenopus tropicalis 57667 R-XTR-110138 https://reactome.org/PathwayBrowser/#/R-XTR-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 57667 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 57667 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 57667 R-XTR-6788798 https://reactome.org/PathwayBrowser/#/R-XTR-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 57667 R-XTR-6788810 https://reactome.org/PathwayBrowser/#/R-XTR-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 57673 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 57673 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 57673 R-BTA-109671 https://reactome.org/PathwayBrowser/#/R-BTA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Bos taurus 57673 R-BTA-110133 https://reactome.org/PathwayBrowser/#/R-BTA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Bos taurus 57673 R-BTA-73788 https://reactome.org/PathwayBrowser/#/R-BTA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Bos taurus 57673 R-BTA-74207 https://reactome.org/PathwayBrowser/#/R-BTA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Bos taurus 57673 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 57673 R-BTA-8953339 https://reactome.org/PathwayBrowser/#/R-BTA-8953339 DNPH1 hydrolyses dGMP IEA Bos taurus 57673 R-CEL-110133 https://reactome.org/PathwayBrowser/#/R-CEL-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Caenorhabditis elegans 57673 R-CEL-73788 https://reactome.org/PathwayBrowser/#/R-CEL-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Caenorhabditis elegans 57673 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 57673 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 57673 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 57673 R-CFA-109671 https://reactome.org/PathwayBrowser/#/R-CFA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Canis familiaris 57673 R-CFA-110133 https://reactome.org/PathwayBrowser/#/R-CFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Canis familiaris 57673 R-CFA-73788 https://reactome.org/PathwayBrowser/#/R-CFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Canis familiaris 57673 R-CFA-74207 https://reactome.org/PathwayBrowser/#/R-CFA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Canis familiaris 57673 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 57673 R-CFA-8953339 https://reactome.org/PathwayBrowser/#/R-CFA-8953339 DNPH1 hydrolyses dGMP IEA Canis familiaris 57673 R-DDI-110133 https://reactome.org/PathwayBrowser/#/R-DDI-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Dictyostelium discoideum 57673 R-DDI-73788 https://reactome.org/PathwayBrowser/#/R-DDI-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Dictyostelium discoideum 57673 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 57673 R-DME-110133 https://reactome.org/PathwayBrowser/#/R-DME-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Drosophila melanogaster 57673 R-DME-73788 https://reactome.org/PathwayBrowser/#/R-DME-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Drosophila melanogaster 57673 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 57673 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 57673 R-DRE-109671 https://reactome.org/PathwayBrowser/#/R-DRE-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Danio rerio 57673 R-DRE-110133 https://reactome.org/PathwayBrowser/#/R-DRE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Danio rerio 57673 R-DRE-73788 https://reactome.org/PathwayBrowser/#/R-DRE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Danio rerio 57673 R-DRE-74207 https://reactome.org/PathwayBrowser/#/R-DRE-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Danio rerio 57673 R-DRE-8953339 https://reactome.org/PathwayBrowser/#/R-DRE-8953339 DNPH1 hydrolyses dGMP IEA Danio rerio 57673 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 57673 R-GGA-109671 https://reactome.org/PathwayBrowser/#/R-GGA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Gallus gallus 57673 R-GGA-110133 https://reactome.org/PathwayBrowser/#/R-GGA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Gallus gallus 57673 R-GGA-73788 https://reactome.org/PathwayBrowser/#/R-GGA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Gallus gallus 57673 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 57673 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 57673 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 57673 R-HSA-109671 https://reactome.org/PathwayBrowser/#/R-HSA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) TAS Homo sapiens 57673 R-HSA-110133 https://reactome.org/PathwayBrowser/#/R-HSA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) TAS Homo sapiens 57673 R-HSA-3245943 https://reactome.org/PathwayBrowser/#/R-HSA-3245943 Viral DNA cleavage by TREX1 TAS Homo sapiens 57673 R-HSA-73788 https://reactome.org/PathwayBrowser/#/R-HSA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) TAS Homo sapiens 57673 R-HSA-74207 https://reactome.org/PathwayBrowser/#/R-HSA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) TAS Homo sapiens 57673 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 57673 R-HSA-8953339 https://reactome.org/PathwayBrowser/#/R-HSA-8953339 DNPH1 hydrolyses dGMP TAS Homo sapiens 57673 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 57673 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 57673 R-MMU-109671 https://reactome.org/PathwayBrowser/#/R-MMU-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Mus musculus 57673 R-MMU-110133 https://reactome.org/PathwayBrowser/#/R-MMU-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Mus musculus 57673 R-MMU-73788 https://reactome.org/PathwayBrowser/#/R-MMU-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Mus musculus 57673 R-MMU-74207 https://reactome.org/PathwayBrowser/#/R-MMU-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Mus musculus 57673 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 57673 R-MMU-8953339 https://reactome.org/PathwayBrowser/#/R-MMU-8953339 DNPH1 hydrolyses dGMP IEA Mus musculus 57673 R-PFA-110133 https://reactome.org/PathwayBrowser/#/R-PFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Plasmodium falciparum 57673 R-PFA-73788 https://reactome.org/PathwayBrowser/#/R-PFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Plasmodium falciparum 57673 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 57673 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 57673 R-RNO-109671 https://reactome.org/PathwayBrowser/#/R-RNO-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Rattus norvegicus 57673 R-RNO-110133 https://reactome.org/PathwayBrowser/#/R-RNO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Rattus norvegicus 57673 R-RNO-73788 https://reactome.org/PathwayBrowser/#/R-RNO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Rattus norvegicus 57673 R-RNO-74207 https://reactome.org/PathwayBrowser/#/R-RNO-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Rattus norvegicus 57673 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 57673 R-RNO-8953339 https://reactome.org/PathwayBrowser/#/R-RNO-8953339 DNPH1 hydrolyses dGMP IEA Rattus norvegicus 57673 R-SCE-110133 https://reactome.org/PathwayBrowser/#/R-SCE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Saccharomyces cerevisiae 57673 R-SCE-73788 https://reactome.org/PathwayBrowser/#/R-SCE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Saccharomyces cerevisiae 57673 R-SPO-110133 https://reactome.org/PathwayBrowser/#/R-SPO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Schizosaccharomyces pombe 57673 R-SPO-73788 https://reactome.org/PathwayBrowser/#/R-SPO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Schizosaccharomyces pombe 57673 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 57673 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 57673 R-SSC-110133 https://reactome.org/PathwayBrowser/#/R-SSC-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Sus scrofa 57673 R-SSC-73788 https://reactome.org/PathwayBrowser/#/R-SSC-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Sus scrofa 57673 R-SSC-74207 https://reactome.org/PathwayBrowser/#/R-SSC-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Sus scrofa 57673 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 57673 R-SSC-8953339 https://reactome.org/PathwayBrowser/#/R-SSC-8953339 DNPH1 hydrolyses dGMP IEA Sus scrofa 57673 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 57673 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 57673 R-XTR-109671 https://reactome.org/PathwayBrowser/#/R-XTR-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Xenopus tropicalis 57673 R-XTR-110133 https://reactome.org/PathwayBrowser/#/R-XTR-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Xenopus tropicalis 57673 R-XTR-73788 https://reactome.org/PathwayBrowser/#/R-XTR-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Xenopus tropicalis 57673 R-XTR-74207 https://reactome.org/PathwayBrowser/#/R-XTR-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Xenopus tropicalis 57673 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 57683 R-BTA-162721 https://reactome.org/PathwayBrowser/#/R-BTA-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Bos taurus 57683 R-BTA-162821 https://reactome.org/PathwayBrowser/#/R-BTA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Bos taurus 57683 R-BTA-162873 https://reactome.org/PathwayBrowser/#/R-BTA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Bos taurus 57683 R-BTA-446188 https://reactome.org/PathwayBrowser/#/R-BTA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Bos taurus 57683 R-BTA-446189 https://reactome.org/PathwayBrowser/#/R-BTA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Bos taurus 57683 R-BTA-446191 https://reactome.org/PathwayBrowser/#/R-BTA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Bos taurus 57683 R-BTA-446195 https://reactome.org/PathwayBrowser/#/R-BTA-446195 DOLK phosphorylates DCHOL to DOLP IEA Bos taurus 57683 R-BTA-446198 https://reactome.org/PathwayBrowser/#/R-BTA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Bos taurus 57683 R-BTA-446200 https://reactome.org/PathwayBrowser/#/R-BTA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Bos taurus 57683 R-BTA-446202 https://reactome.org/PathwayBrowser/#/R-BTA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Bos taurus 57683 R-BTA-446214 https://reactome.org/PathwayBrowser/#/R-BTA-446214 Synthesis of dolichyl-phosphate-glucose IEA Bos taurus 57683 R-BTA-446215 https://reactome.org/PathwayBrowser/#/R-BTA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Bos taurus 57683 R-BTA-446216 https://reactome.org/PathwayBrowser/#/R-BTA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Bos taurus 57683 R-BTA-5615637 https://reactome.org/PathwayBrowser/#/R-BTA-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Bos taurus 57683 R-CEL-162821 https://reactome.org/PathwayBrowser/#/R-CEL-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Caenorhabditis elegans 57683 R-CEL-162873 https://reactome.org/PathwayBrowser/#/R-CEL-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Caenorhabditis elegans 57683 R-CEL-446188 https://reactome.org/PathwayBrowser/#/R-CEL-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Caenorhabditis elegans 57683 R-CEL-446189 https://reactome.org/PathwayBrowser/#/R-CEL-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Caenorhabditis elegans 57683 R-CEL-446191 https://reactome.org/PathwayBrowser/#/R-CEL-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Caenorhabditis elegans 57683 R-CEL-446198 https://reactome.org/PathwayBrowser/#/R-CEL-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Caenorhabditis elegans 57683 R-CEL-446202 https://reactome.org/PathwayBrowser/#/R-CEL-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Caenorhabditis elegans 57683 R-CEL-446214 https://reactome.org/PathwayBrowser/#/R-CEL-446214 Synthesis of dolichyl-phosphate-glucose IEA Caenorhabditis elegans 57683 R-CEL-446215 https://reactome.org/PathwayBrowser/#/R-CEL-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Caenorhabditis elegans 57683 R-CEL-446216 https://reactome.org/PathwayBrowser/#/R-CEL-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Caenorhabditis elegans 57683 R-CFA-162821 https://reactome.org/PathwayBrowser/#/R-CFA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 57683 R-CFA-162830 https://reactome.org/PathwayBrowser/#/R-CFA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 57683 R-CFA-162873 https://reactome.org/PathwayBrowser/#/R-CFA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 57683 R-CFA-446188 https://reactome.org/PathwayBrowser/#/R-CFA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Canis familiaris 57683 R-CFA-446189 https://reactome.org/PathwayBrowser/#/R-CFA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Canis familiaris 57683 R-CFA-446191 https://reactome.org/PathwayBrowser/#/R-CFA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Canis familiaris 57683 R-CFA-446195 https://reactome.org/PathwayBrowser/#/R-CFA-446195 DOLK phosphorylates DCHOL to DOLP IEA Canis familiaris 57683 R-CFA-446198 https://reactome.org/PathwayBrowser/#/R-CFA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Canis familiaris 57683 R-CFA-446200 https://reactome.org/PathwayBrowser/#/R-CFA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Canis familiaris 57683 R-CFA-446202 https://reactome.org/PathwayBrowser/#/R-CFA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Canis familiaris 57683 R-CFA-446214 https://reactome.org/PathwayBrowser/#/R-CFA-446214 Synthesis of dolichyl-phosphate-glucose IEA Canis familiaris 57683 R-CFA-446215 https://reactome.org/PathwayBrowser/#/R-CFA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Canis familiaris 57683 R-CFA-446216 https://reactome.org/PathwayBrowser/#/R-CFA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Canis familiaris 57683 R-CFA-5615637 https://reactome.org/PathwayBrowser/#/R-CFA-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Canis familiaris 57683 R-DDI-162821 https://reactome.org/PathwayBrowser/#/R-DDI-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 57683 R-DDI-162830 https://reactome.org/PathwayBrowser/#/R-DDI-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 57683 R-DDI-162873 https://reactome.org/PathwayBrowser/#/R-DDI-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 57683 R-DDI-446188 https://reactome.org/PathwayBrowser/#/R-DDI-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Dictyostelium discoideum 57683 R-DDI-446189 https://reactome.org/PathwayBrowser/#/R-DDI-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Dictyostelium discoideum 57683 R-DDI-446191 https://reactome.org/PathwayBrowser/#/R-DDI-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Dictyostelium discoideum 57683 R-DDI-446195 https://reactome.org/PathwayBrowser/#/R-DDI-446195 DOLK phosphorylates DCHOL to DOLP IEA Dictyostelium discoideum 57683 R-DDI-446198 https://reactome.org/PathwayBrowser/#/R-DDI-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Dictyostelium discoideum 57683 R-DDI-446200 https://reactome.org/PathwayBrowser/#/R-DDI-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Dictyostelium discoideum 57683 R-DDI-446202 https://reactome.org/PathwayBrowser/#/R-DDI-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Dictyostelium discoideum 57683 R-DDI-446214 https://reactome.org/PathwayBrowser/#/R-DDI-446214 Synthesis of dolichyl-phosphate-glucose IEA Dictyostelium discoideum 57683 R-DDI-446215 https://reactome.org/PathwayBrowser/#/R-DDI-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Dictyostelium discoideum 57683 R-DDI-446216 https://reactome.org/PathwayBrowser/#/R-DDI-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Dictyostelium discoideum 57683 R-DME-162821 https://reactome.org/PathwayBrowser/#/R-DME-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 57683 R-DME-162830 https://reactome.org/PathwayBrowser/#/R-DME-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 57683 R-DME-162873 https://reactome.org/PathwayBrowser/#/R-DME-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 57683 R-DME-446188 https://reactome.org/PathwayBrowser/#/R-DME-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Drosophila melanogaster 57683 R-DME-446189 https://reactome.org/PathwayBrowser/#/R-DME-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Drosophila melanogaster 57683 R-DME-446191 https://reactome.org/PathwayBrowser/#/R-DME-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Drosophila melanogaster 57683 R-DME-446195 https://reactome.org/PathwayBrowser/#/R-DME-446195 DOLK phosphorylates DCHOL to DOLP IEA Drosophila melanogaster 57683 R-DME-446198 https://reactome.org/PathwayBrowser/#/R-DME-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Drosophila melanogaster 57683 R-DME-446202 https://reactome.org/PathwayBrowser/#/R-DME-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Drosophila melanogaster 57683 R-DME-446214 https://reactome.org/PathwayBrowser/#/R-DME-446214 Synthesis of dolichyl-phosphate-glucose IEA Drosophila melanogaster 57683 R-DME-446215 https://reactome.org/PathwayBrowser/#/R-DME-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Drosophila melanogaster 57683 R-DME-446216 https://reactome.org/PathwayBrowser/#/R-DME-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Drosophila melanogaster 57683 R-DME-5615637 https://reactome.org/PathwayBrowser/#/R-DME-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Drosophila melanogaster 57683 R-DRE-162721 https://reactome.org/PathwayBrowser/#/R-DRE-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Danio rerio 57683 R-DRE-162821 https://reactome.org/PathwayBrowser/#/R-DRE-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Danio rerio 57683 R-DRE-446188 https://reactome.org/PathwayBrowser/#/R-DRE-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Danio rerio 57683 R-DRE-446189 https://reactome.org/PathwayBrowser/#/R-DRE-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Danio rerio 57683 R-DRE-446191 https://reactome.org/PathwayBrowser/#/R-DRE-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Danio rerio 57683 R-DRE-446195 https://reactome.org/PathwayBrowser/#/R-DRE-446195 DOLK phosphorylates DCHOL to DOLP IEA Danio rerio 57683 R-DRE-446198 https://reactome.org/PathwayBrowser/#/R-DRE-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Danio rerio 57683 R-DRE-446200 https://reactome.org/PathwayBrowser/#/R-DRE-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Danio rerio 57683 R-DRE-446214 https://reactome.org/PathwayBrowser/#/R-DRE-446214 Synthesis of dolichyl-phosphate-glucose IEA Danio rerio 57683 R-DRE-5615637 https://reactome.org/PathwayBrowser/#/R-DRE-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Danio rerio 57683 R-GGA-162830 https://reactome.org/PathwayBrowser/#/R-GGA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Gallus gallus 57683 R-GGA-162873 https://reactome.org/PathwayBrowser/#/R-GGA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Gallus gallus 57683 R-GGA-446188 https://reactome.org/PathwayBrowser/#/R-GGA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Gallus gallus 57683 R-GGA-446189 https://reactome.org/PathwayBrowser/#/R-GGA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Gallus gallus 57683 R-GGA-446191 https://reactome.org/PathwayBrowser/#/R-GGA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Gallus gallus 57683 R-GGA-446195 https://reactome.org/PathwayBrowser/#/R-GGA-446195 DOLK phosphorylates DCHOL to DOLP IEA Gallus gallus 57683 R-GGA-446198 https://reactome.org/PathwayBrowser/#/R-GGA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Gallus gallus 57683 R-GGA-446200 https://reactome.org/PathwayBrowser/#/R-GGA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Gallus gallus 57683 R-GGA-446202 https://reactome.org/PathwayBrowser/#/R-GGA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Gallus gallus 57683 R-GGA-446214 https://reactome.org/PathwayBrowser/#/R-GGA-446214 Synthesis of dolichyl-phosphate-glucose IEA Gallus gallus 57683 R-GGA-446215 https://reactome.org/PathwayBrowser/#/R-GGA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Gallus gallus 57683 R-GGA-446216 https://reactome.org/PathwayBrowser/#/R-GGA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Gallus gallus 57683 R-GGA-5615637 https://reactome.org/PathwayBrowser/#/R-GGA-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Gallus gallus 57683 R-HSA-162721 https://reactome.org/PathwayBrowser/#/R-HSA-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose TAS Homo sapiens 57683 R-HSA-162821 https://reactome.org/PathwayBrowser/#/R-HSA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 57683 R-HSA-162830 https://reactome.org/PathwayBrowser/#/R-HSA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 57683 R-HSA-162873 https://reactome.org/PathwayBrowser/#/R-HSA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 57683 R-HSA-446188 https://reactome.org/PathwayBrowser/#/R-HSA-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 TAS Homo sapiens 57683 R-HSA-446189 https://reactome.org/PathwayBrowser/#/R-HSA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 TAS Homo sapiens 57683 R-HSA-446191 https://reactome.org/PathwayBrowser/#/R-HSA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate TAS Homo sapiens 57683 R-HSA-446194 https://reactome.org/PathwayBrowser/#/R-HSA-446194 Addition of a third glucose to the N-glycan precursor by an ALG10 homologue IEA Homo sapiens 57683 R-HSA-446195 https://reactome.org/PathwayBrowser/#/R-HSA-446195 DOLK phosphorylates DCHOL to DOLP TAS Homo sapiens 57683 R-HSA-446198 https://reactome.org/PathwayBrowser/#/R-HSA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 TAS Homo sapiens 57683 R-HSA-446200 https://reactome.org/PathwayBrowser/#/R-HSA-446200 DOLPP1 dephosphorylates DOLDP to DOLP TAS Homo sapiens 57683 R-HSA-446202 https://reactome.org/PathwayBrowser/#/R-HSA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 TAS Homo sapiens 57683 R-HSA-446209 https://reactome.org/PathwayBrowser/#/R-HSA-446209 Transfer of N-glycan to the protein TAS Homo sapiens 57683 R-HSA-446214 https://reactome.org/PathwayBrowser/#/R-HSA-446214 Synthesis of dolichyl-phosphate-glucose TAS Homo sapiens 57683 R-HSA-446215 https://reactome.org/PathwayBrowser/#/R-HSA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 TAS Homo sapiens 57683 R-HSA-446216 https://reactome.org/PathwayBrowser/#/R-HSA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 TAS Homo sapiens 57683 R-HSA-4549334 https://reactome.org/PathwayBrowser/#/R-HSA-4549334 Defective DPAGT1 does not transfer GlcNAc to DOLP TAS Homo sapiens 57683 R-HSA-548884 https://reactome.org/PathwayBrowser/#/R-HSA-548884 UGGT1,2 transfers glucose from DbGP to (un)folded protein:(GlcNAc)2 (Man)8b TAS Homo sapiens 57683 R-HSA-5615637 https://reactome.org/PathwayBrowser/#/R-HSA-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) TAS Homo sapiens 57683 R-HSA-9694793 https://reactome.org/PathwayBrowser/#/R-HSA-9694793 Spike protein gets N-glycosylated TAS Homo sapiens 57683 R-MMU-162721 https://reactome.org/PathwayBrowser/#/R-MMU-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Mus musculus 57683 R-MMU-162821 https://reactome.org/PathwayBrowser/#/R-MMU-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 57683 R-MMU-162830 https://reactome.org/PathwayBrowser/#/R-MMU-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 57683 R-MMU-162873 https://reactome.org/PathwayBrowser/#/R-MMU-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 57683 R-MMU-446188 https://reactome.org/PathwayBrowser/#/R-MMU-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Mus musculus 57683 R-MMU-446189 https://reactome.org/PathwayBrowser/#/R-MMU-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Mus musculus 57683 R-MMU-446191 https://reactome.org/PathwayBrowser/#/R-MMU-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Mus musculus 57683 R-MMU-446195 https://reactome.org/PathwayBrowser/#/R-MMU-446195 DOLK phosphorylates DCHOL to DOLP IEA Mus musculus 57683 R-MMU-446198 https://reactome.org/PathwayBrowser/#/R-MMU-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Mus musculus 57683 R-MMU-446200 https://reactome.org/PathwayBrowser/#/R-MMU-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Mus musculus 57683 R-MMU-446202 https://reactome.org/PathwayBrowser/#/R-MMU-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Mus musculus 57683 R-MMU-446214 https://reactome.org/PathwayBrowser/#/R-MMU-446214 Synthesis of dolichyl-phosphate-glucose IEA Mus musculus 57683 R-MMU-446215 https://reactome.org/PathwayBrowser/#/R-MMU-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Mus musculus 57683 R-MMU-446216 https://reactome.org/PathwayBrowser/#/R-MMU-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Mus musculus 57683 R-MMU-5615637 https://reactome.org/PathwayBrowser/#/R-MMU-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Mus musculus 57683 R-PFA-162821 https://reactome.org/PathwayBrowser/#/R-PFA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Plasmodium falciparum 57683 R-PFA-162873 https://reactome.org/PathwayBrowser/#/R-PFA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Plasmodium falciparum 57683 R-PFA-446191 https://reactome.org/PathwayBrowser/#/R-PFA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Plasmodium falciparum 57683 R-RNO-162721 https://reactome.org/PathwayBrowser/#/R-RNO-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Rattus norvegicus 57683 R-RNO-162821 https://reactome.org/PathwayBrowser/#/R-RNO-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 57683 R-RNO-162830 https://reactome.org/PathwayBrowser/#/R-RNO-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 57683 R-RNO-162873 https://reactome.org/PathwayBrowser/#/R-RNO-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 57683 R-RNO-446188 https://reactome.org/PathwayBrowser/#/R-RNO-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Rattus norvegicus 57683 R-RNO-446189 https://reactome.org/PathwayBrowser/#/R-RNO-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Rattus norvegicus 57683 R-RNO-446191 https://reactome.org/PathwayBrowser/#/R-RNO-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Rattus norvegicus 57683 R-RNO-446195 https://reactome.org/PathwayBrowser/#/R-RNO-446195 DOLK phosphorylates DCHOL to DOLP IEA Rattus norvegicus 57683 R-RNO-446198 https://reactome.org/PathwayBrowser/#/R-RNO-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Rattus norvegicus 57683 R-RNO-446200 https://reactome.org/PathwayBrowser/#/R-RNO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Rattus norvegicus 57683 R-RNO-446202 https://reactome.org/PathwayBrowser/#/R-RNO-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Rattus norvegicus 57683 R-RNO-446214 https://reactome.org/PathwayBrowser/#/R-RNO-446214 Synthesis of dolichyl-phosphate-glucose IEA Rattus norvegicus 57683 R-RNO-446215 https://reactome.org/PathwayBrowser/#/R-RNO-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Rattus norvegicus 57683 R-RNO-446216 https://reactome.org/PathwayBrowser/#/R-RNO-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Rattus norvegicus 57683 R-RNO-5615637 https://reactome.org/PathwayBrowser/#/R-RNO-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Rattus norvegicus 57683 R-SCE-162821 https://reactome.org/PathwayBrowser/#/R-SCE-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Saccharomyces cerevisiae 57683 R-SCE-162873 https://reactome.org/PathwayBrowser/#/R-SCE-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Saccharomyces cerevisiae 57683 R-SCE-446188 https://reactome.org/PathwayBrowser/#/R-SCE-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Saccharomyces cerevisiae 57683 R-SCE-446189 https://reactome.org/PathwayBrowser/#/R-SCE-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Saccharomyces cerevisiae 57683 R-SCE-446191 https://reactome.org/PathwayBrowser/#/R-SCE-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Saccharomyces cerevisiae 57683 R-SCE-446195 https://reactome.org/PathwayBrowser/#/R-SCE-446195 DOLK phosphorylates DCHOL to DOLP IEA Saccharomyces cerevisiae 57683 R-SCE-446198 https://reactome.org/PathwayBrowser/#/R-SCE-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Saccharomyces cerevisiae 57683 R-SCE-446202 https://reactome.org/PathwayBrowser/#/R-SCE-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Saccharomyces cerevisiae 57683 R-SCE-446214 https://reactome.org/PathwayBrowser/#/R-SCE-446214 Synthesis of dolichyl-phosphate-glucose IEA Saccharomyces cerevisiae 57683 R-SCE-446215 https://reactome.org/PathwayBrowser/#/R-SCE-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Saccharomyces cerevisiae 57683 R-SCE-446216 https://reactome.org/PathwayBrowser/#/R-SCE-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Saccharomyces cerevisiae 57683 R-SCE-449661 https://reactome.org/PathwayBrowser/#/R-SCE-449661 Addition of a third glucose to the N-glycan skeleton by Alg10 TAS Saccharomyces cerevisiae 57683 R-SPO-162821 https://reactome.org/PathwayBrowser/#/R-SPO-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Schizosaccharomyces pombe 57683 R-SPO-162873 https://reactome.org/PathwayBrowser/#/R-SPO-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Schizosaccharomyces pombe 57683 R-SPO-446188 https://reactome.org/PathwayBrowser/#/R-SPO-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Schizosaccharomyces pombe 57683 R-SPO-446189 https://reactome.org/PathwayBrowser/#/R-SPO-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Schizosaccharomyces pombe 57683 R-SPO-446191 https://reactome.org/PathwayBrowser/#/R-SPO-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Schizosaccharomyces pombe 57683 R-SPO-446195 https://reactome.org/PathwayBrowser/#/R-SPO-446195 DOLK phosphorylates DCHOL to DOLP IEA Schizosaccharomyces pombe 57683 R-SPO-446198 https://reactome.org/PathwayBrowser/#/R-SPO-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Schizosaccharomyces pombe 57683 R-SPO-446200 https://reactome.org/PathwayBrowser/#/R-SPO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Schizosaccharomyces pombe 57683 R-SPO-446202 https://reactome.org/PathwayBrowser/#/R-SPO-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Schizosaccharomyces pombe 57683 R-SPO-446214 https://reactome.org/PathwayBrowser/#/R-SPO-446214 Synthesis of dolichyl-phosphate-glucose IEA Schizosaccharomyces pombe 57683 R-SPO-446215 https://reactome.org/PathwayBrowser/#/R-SPO-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Schizosaccharomyces pombe 57683 R-SPO-446216 https://reactome.org/PathwayBrowser/#/R-SPO-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Schizosaccharomyces pombe 57683 R-SSC-162721 https://reactome.org/PathwayBrowser/#/R-SSC-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Sus scrofa 57683 R-SSC-162821 https://reactome.org/PathwayBrowser/#/R-SSC-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Sus scrofa 57683 R-SSC-162873 https://reactome.org/PathwayBrowser/#/R-SSC-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Sus scrofa 57683 R-SSC-446188 https://reactome.org/PathwayBrowser/#/R-SSC-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Sus scrofa 57683 R-SSC-446189 https://reactome.org/PathwayBrowser/#/R-SSC-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Sus scrofa 57683 R-SSC-446191 https://reactome.org/PathwayBrowser/#/R-SSC-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Sus scrofa 57683 R-SSC-446195 https://reactome.org/PathwayBrowser/#/R-SSC-446195 DOLK phosphorylates DCHOL to DOLP IEA Sus scrofa 57683 R-SSC-446198 https://reactome.org/PathwayBrowser/#/R-SSC-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Sus scrofa 57683 R-SSC-446200 https://reactome.org/PathwayBrowser/#/R-SSC-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Sus scrofa 57683 R-SSC-446202 https://reactome.org/PathwayBrowser/#/R-SSC-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Sus scrofa 57683 R-SSC-446214 https://reactome.org/PathwayBrowser/#/R-SSC-446214 Synthesis of dolichyl-phosphate-glucose IEA Sus scrofa 57683 R-SSC-446215 https://reactome.org/PathwayBrowser/#/R-SSC-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Sus scrofa 57683 R-SSC-446216 https://reactome.org/PathwayBrowser/#/R-SSC-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Sus scrofa 57683 R-SSC-5615637 https://reactome.org/PathwayBrowser/#/R-SSC-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Sus scrofa 57683 R-XTR-162721 https://reactome.org/PathwayBrowser/#/R-XTR-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Xenopus tropicalis 57683 R-XTR-162821 https://reactome.org/PathwayBrowser/#/R-XTR-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 57683 R-XTR-162830 https://reactome.org/PathwayBrowser/#/R-XTR-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 57683 R-XTR-162873 https://reactome.org/PathwayBrowser/#/R-XTR-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 57683 R-XTR-446188 https://reactome.org/PathwayBrowser/#/R-XTR-446188 ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 IEA Xenopus tropicalis 57683 R-XTR-446189 https://reactome.org/PathwayBrowser/#/R-XTR-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Xenopus tropicalis 57683 R-XTR-446191 https://reactome.org/PathwayBrowser/#/R-XTR-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Xenopus tropicalis 57683 R-XTR-446195 https://reactome.org/PathwayBrowser/#/R-XTR-446195 DOLK phosphorylates DCHOL to DOLP IEA Xenopus tropicalis 57683 R-XTR-446200 https://reactome.org/PathwayBrowser/#/R-XTR-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Xenopus tropicalis 57683 R-XTR-446202 https://reactome.org/PathwayBrowser/#/R-XTR-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Xenopus tropicalis 57683 R-XTR-446214 https://reactome.org/PathwayBrowser/#/R-XTR-446214 Synthesis of dolichyl-phosphate-glucose IEA Xenopus tropicalis 57683 R-XTR-446215 https://reactome.org/PathwayBrowser/#/R-XTR-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Xenopus tropicalis 57683 R-XTR-446216 https://reactome.org/PathwayBrowser/#/R-XTR-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Xenopus tropicalis 57683 R-XTR-5615637 https://reactome.org/PathwayBrowser/#/R-XTR-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Xenopus tropicalis 57692 R-AMA-1614571 https://reactome.org/PathwayBrowser/#/R-AMA-1614571 Sqr oxidizes sulfide to bound persulfide TAS Arenicola marina 57692 R-BTA-109341 https://reactome.org/PathwayBrowser/#/R-BTA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Bos taurus 57692 R-BTA-1222376 https://reactome.org/PathwayBrowser/#/R-BTA-1222376 NOX2 generates superoxide from oxygen IEA Bos taurus 57692 R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 57692 R-BTA-141186 https://reactome.org/PathwayBrowser/#/R-BTA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Bos taurus 57692 R-BTA-141200 https://reactome.org/PathwayBrowser/#/R-BTA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Bos taurus 57692 R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus 57692 R-BTA-141348 https://reactome.org/PathwayBrowser/#/R-BTA-141348 PAO:FAD oxidises NASPM to PTCN IEA Bos taurus 57692 R-BTA-141351 https://reactome.org/PathwayBrowser/#/R-BTA-141351 PAOX:FAD oxidises NASPN to SPM IEA Bos taurus 57692 R-BTA-1497784 https://reactome.org/PathwayBrowser/#/R-BTA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Bos taurus 57692 R-BTA-1497796 https://reactome.org/PathwayBrowser/#/R-BTA-1497796 BH2 binding can lead to eNOS uncoupling IEA Bos taurus 57692 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 57692 R-BTA-163217 https://reactome.org/PathwayBrowser/#/R-BTA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Bos taurus 57692 R-BTA-1655453 https://reactome.org/PathwayBrowser/#/R-BTA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Bos taurus 57692 R-BTA-165642 https://reactome.org/PathwayBrowser/#/R-BTA-165642 Transfer of electrons through the bovine succinate dehydrogenase complex TAS Bos taurus 57692 R-BTA-174374 https://reactome.org/PathwayBrowser/#/R-BTA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Bos taurus 57692 R-BTA-188467 https://reactome.org/PathwayBrowser/#/R-BTA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Bos taurus 57692 R-BTA-189423 https://reactome.org/PathwayBrowser/#/R-BTA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Bos taurus 57692 R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 57692 R-BTA-192335 https://reactome.org/PathwayBrowser/#/R-BTA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Bos taurus 57692 R-BTA-193369 https://reactome.org/PathwayBrowser/#/R-BTA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Bos taurus 57692 R-BTA-196929 https://reactome.org/PathwayBrowser/#/R-BTA-196929 FLAD1 phosphorylates FMN IEA Bos taurus 57692 R-BTA-196955 https://reactome.org/PathwayBrowser/#/R-BTA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Bos taurus 57692 R-BTA-198824 https://reactome.org/PathwayBrowser/#/R-BTA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Bos taurus 57692 R-BTA-202110 https://reactome.org/PathwayBrowser/#/R-BTA-202110 eNOS:Caveolin-1 complex binds to CaM IEA Bos taurus 57692 R-BTA-202111 https://reactome.org/PathwayBrowser/#/R-BTA-202111 AKT1 phosphorylates eNOS IEA Bos taurus 57692 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 57692 R-BTA-202129 https://reactome.org/PathwayBrowser/#/R-BTA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Bos taurus 57692 R-BTA-202132 https://reactome.org/PathwayBrowser/#/R-BTA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Bos taurus 57692 R-BTA-202144 https://reactome.org/PathwayBrowser/#/R-BTA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Bos taurus 57692 R-BTA-203553 https://reactome.org/PathwayBrowser/#/R-BTA-203553 eNOS binds NOSIP IEA Bos taurus 57692 R-BTA-203565 https://reactome.org/PathwayBrowser/#/R-BTA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Bos taurus 57692 R-BTA-203613 https://reactome.org/PathwayBrowser/#/R-BTA-203613 depalmitoylation of eNOS IEA Bos taurus 57692 R-BTA-203625 https://reactome.org/PathwayBrowser/#/R-BTA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Bos taurus 57692 R-BTA-203680 https://reactome.org/PathwayBrowser/#/R-BTA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Bos taurus 57692 R-BTA-203700 https://reactome.org/PathwayBrowser/#/R-BTA-203700 eNOS translocation from Golgi to Caveolae IEA Bos taurus 57692 R-BTA-203712 https://reactome.org/PathwayBrowser/#/R-BTA-203712 eNOS associates with Caveolin-1 IEA Bos taurus 57692 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 57692 R-BTA-204169 https://reactome.org/PathwayBrowser/#/R-BTA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Bos taurus 57692 R-BTA-2066787 https://reactome.org/PathwayBrowser/#/R-BTA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Bos taurus 57692 R-BTA-2160492 https://reactome.org/PathwayBrowser/#/R-BTA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Bos taurus 57692 R-BTA-2162186 https://reactome.org/PathwayBrowser/#/R-BTA-2162186 COQ3 methylates DeMQ10H2 IEA Bos taurus 57692 R-BTA-2162188 https://reactome.org/PathwayBrowser/#/R-BTA-2162188 COQ5 methylates MDMQ10H2 IEA Bos taurus 57692 R-BTA-2162193 https://reactome.org/PathwayBrowser/#/R-BTA-2162193 COQ3 methylates DHDB IEA Bos taurus 57692 R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 57692 R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 57692 R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 57692 R-BTA-2395512 https://reactome.org/PathwayBrowser/#/R-BTA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Bos taurus 57692 R-BTA-2395517 https://reactome.org/PathwayBrowser/#/R-BTA-2395517 NADPH transfers electrons to FDXR IEA Bos taurus 57692 R-BTA-2408527 https://reactome.org/PathwayBrowser/#/R-BTA-2408527 SeO3(2-) is reduced to H2Se by TXNRD1 TAS Bos taurus 57692 R-BTA-3149518 https://reactome.org/PathwayBrowser/#/R-BTA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Bos taurus 57692 R-BTA-3149539 https://reactome.org/PathwayBrowser/#/R-BTA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Bos taurus 57692 R-BTA-3159253 https://reactome.org/PathwayBrowser/#/R-BTA-3159253 MMAB adenosylates cob(I)alamin IEA Bos taurus 57692 R-BTA-3165230 https://reactome.org/PathwayBrowser/#/R-BTA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Bos taurus 57692 R-BTA-3204311 https://reactome.org/PathwayBrowser/#/R-BTA-3204311 AOX1 oxidises PXL to PDXate IEA Bos taurus 57692 R-BTA-3204318 https://reactome.org/PathwayBrowser/#/R-BTA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Bos taurus 57692 R-BTA-3323050 https://reactome.org/PathwayBrowser/#/R-BTA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Bos taurus 57692 R-BTA-3323079 https://reactome.org/PathwayBrowser/#/R-BTA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 57692 R-BTA-374909 https://reactome.org/PathwayBrowser/#/R-BTA-374909 Catabolism of Noradrenaline IEA Bos taurus 57692 R-BTA-379382 https://reactome.org/PathwayBrowser/#/R-BTA-379382 MAOA:FAD deaminates DA to DOPAC IEA Bos taurus 57692 R-BTA-379395 https://reactome.org/PathwayBrowser/#/R-BTA-379395 MAOA:FAD deaminates 3MT to HVA IEA Bos taurus 57692 R-BTA-389821 https://reactome.org/PathwayBrowser/#/R-BTA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Bos taurus 57692 R-BTA-389889 https://reactome.org/PathwayBrowser/#/R-BTA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Bos taurus 57692 R-BTA-389891 https://reactome.org/PathwayBrowser/#/R-BTA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Bos taurus 57692 R-BTA-390256 https://reactome.org/PathwayBrowser/#/R-BTA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Bos taurus 57692 R-BTA-390427 https://reactome.org/PathwayBrowser/#/R-BTA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Bos taurus 57692 R-BTA-5218827 https://reactome.org/PathwayBrowser/#/R-BTA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Bos taurus 57692 R-BTA-5218841 https://reactome.org/PathwayBrowser/#/R-BTA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Bos taurus 57692 R-BTA-5263614 https://reactome.org/PathwayBrowser/#/R-BTA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Bos taurus 57692 R-BTA-5263616 https://reactome.org/PathwayBrowser/#/R-BTA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Bos taurus 57692 R-BTA-5693148 https://reactome.org/PathwayBrowser/#/R-BTA-5693148 BCKDK phosphorylates BCKDH IEA Bos taurus 57692 R-BTA-5693153 https://reactome.org/PathwayBrowser/#/R-BTA-5693153 PPM1K dephosphorylates p-BCKDH IEA Bos taurus 57692 R-BTA-5694018 https://reactome.org/PathwayBrowser/#/R-BTA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Bos taurus 57692 R-BTA-5695980 https://reactome.org/PathwayBrowser/#/R-BTA-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Bos taurus 57692 R-BTA-5695989 https://reactome.org/PathwayBrowser/#/R-BTA-5695989 ACAD11 dehydrogenates BH-CoA IEA Bos taurus 57692 R-BTA-6784224 https://reactome.org/PathwayBrowser/#/R-BTA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Bos taurus 57692 R-BTA-6797653 https://reactome.org/PathwayBrowser/#/R-BTA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Bos taurus 57692 R-BTA-6797913 https://reactome.org/PathwayBrowser/#/R-BTA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Bos taurus 57692 R-BTA-6799178 https://reactome.org/PathwayBrowser/#/R-BTA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Bos taurus 57692 R-BTA-6799179 https://reactome.org/PathwayBrowser/#/R-BTA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Bos taurus 57692 R-BTA-6799191 https://reactome.org/PathwayBrowser/#/R-BTA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Bos taurus 57692 R-BTA-6799196 https://reactome.org/PathwayBrowser/#/R-BTA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Bos taurus 57692 R-BTA-6799197 https://reactome.org/PathwayBrowser/#/R-BTA-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Bos taurus 57692 R-BTA-6799202 https://reactome.org/PathwayBrowser/#/R-BTA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Bos taurus 57692 R-BTA-6799203 https://reactome.org/PathwayBrowser/#/R-BTA-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Bos taurus 57692 R-BTA-6800868 https://reactome.org/PathwayBrowser/#/R-BTA-6800868 NDUF subunits bind to form the IP subcomplex IEA Bos taurus 57692 R-BTA-6810076 https://reactome.org/PathwayBrowser/#/R-BTA-6810076 DDO oxidizes D-Asp to OA IEA Bos taurus 57692 R-BTA-70670 https://reactome.org/PathwayBrowser/#/R-BTA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Bos taurus 57692 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 57692 R-BTA-70745 https://reactome.org/PathwayBrowser/#/R-BTA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Bos taurus 57692 R-BTA-70800 https://reactome.org/PathwayBrowser/#/R-BTA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Bos taurus 57692 R-BTA-70859 https://reactome.org/PathwayBrowser/#/R-BTA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Bos taurus 57692 R-BTA-71037 https://reactome.org/PathwayBrowser/#/R-BTA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Bos taurus 57692 R-BTA-71046 https://reactome.org/PathwayBrowser/#/R-BTA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Bos taurus 57692 R-BTA-71401 https://reactome.org/PathwayBrowser/#/R-BTA-71401 OGDH dimer decarboxylates 2-OG IEA Bos taurus 57692 R-BTA-71682 https://reactome.org/PathwayBrowser/#/R-BTA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 57692 R-BTA-73585 https://reactome.org/PathwayBrowser/#/R-BTA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Bos taurus 57692 R-BTA-73616 https://reactome.org/PathwayBrowser/#/R-BTA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Bos taurus 57692 R-BTA-73646 https://reactome.org/PathwayBrowser/#/R-BTA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Bos taurus 57692 R-BTA-74247 https://reactome.org/PathwayBrowser/#/R-BTA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Bos taurus 57692 R-BTA-74258 https://reactome.org/PathwayBrowser/#/R-BTA-74258 XDH oxidizes xanthine to form urate IEA Bos taurus 57692 R-BTA-75879 https://reactome.org/PathwayBrowser/#/R-BTA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Bos taurus 57692 R-BTA-77263 https://reactome.org/PathwayBrowser/#/R-BTA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Bos taurus 57692 R-BTA-77274 https://reactome.org/PathwayBrowser/#/R-BTA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Bos taurus 57692 R-BTA-77299 https://reactome.org/PathwayBrowser/#/R-BTA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Bos taurus 57692 R-BTA-77319 https://reactome.org/PathwayBrowser/#/R-BTA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Bos taurus 57692 R-BTA-77327 https://reactome.org/PathwayBrowser/#/R-BTA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Bos taurus 57692 R-BTA-77338 https://reactome.org/PathwayBrowser/#/R-BTA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Bos taurus 57692 R-BTA-77345 https://reactome.org/PathwayBrowser/#/R-BTA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Bos taurus 57692 R-BTA-880007 https://reactome.org/PathwayBrowser/#/R-BTA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Bos taurus 57692 R-BTA-880050 https://reactome.org/PathwayBrowser/#/R-BTA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Bos taurus 57692 R-BTA-8936519 https://reactome.org/PathwayBrowser/#/R-BTA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Bos taurus 57692 R-BTA-8955817 https://reactome.org/PathwayBrowser/#/R-BTA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Bos taurus 57692 R-BTA-8956458 https://reactome.org/PathwayBrowser/#/R-BTA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Bos taurus 57692 R-BTA-9013145 https://reactome.org/PathwayBrowser/#/R-BTA-9013145 RAC1 binds effectors at the plasma membrane IEA Bos taurus 57692 R-BTA-9018808 https://reactome.org/PathwayBrowser/#/R-BTA-9018808 RAC3 binds effectors at the plasma membrane IEA Bos taurus 57692 R-BTA-917811 https://reactome.org/PathwayBrowser/#/R-BTA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Bos taurus 57692 R-BTA-9677917 https://reactome.org/PathwayBrowser/#/R-BTA-9677917 MAOA inhibitors bind MAOA:FAD IEA Bos taurus 57692 R-BTA-9677929 https://reactome.org/PathwayBrowser/#/R-BTA-9677929 MAOB inhibitors bind MAOB:FAD IEA Bos taurus 57692 R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 57692 R-BTA-9727349 https://reactome.org/PathwayBrowser/#/R-BTA-9727349 XDH dehydrogenates xanthine to form urate IEA Bos taurus 57692 R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 57692 R-BTA-9853499 https://reactome.org/PathwayBrowser/#/R-BTA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 57692 R-BTA-9853512 https://reactome.org/PathwayBrowser/#/R-BTA-9853512 DLST transfers succinyl to CoA IEA Bos taurus 57692 R-BTA-9854672 https://reactome.org/PathwayBrowser/#/R-BTA-9854672 FAD attaches to SDHA IEA Bos taurus 57692 R-BTA-9861616 https://reactome.org/PathwayBrowser/#/R-BTA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 57692 R-BTA-9861667 https://reactome.org/PathwayBrowser/#/R-BTA-9861667 DLAT trimer transfers acetyl to CoA IEA Bos taurus 57692 R-BTA-9861734 https://reactome.org/PathwayBrowser/#/R-BTA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Bos taurus 57692 R-CEL-109341 https://reactome.org/PathwayBrowser/#/R-CEL-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Caenorhabditis elegans 57692 R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 57692 R-CEL-141348 https://reactome.org/PathwayBrowser/#/R-CEL-141348 PAO:FAD oxidises NASPM to PTCN IEA Caenorhabditis elegans 57692 R-CEL-141351 https://reactome.org/PathwayBrowser/#/R-CEL-141351 PAOX:FAD oxidises NASPN to SPM IEA Caenorhabditis elegans 57692 R-CEL-1497784 https://reactome.org/PathwayBrowser/#/R-CEL-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Caenorhabditis elegans 57692 R-CEL-1497796 https://reactome.org/PathwayBrowser/#/R-CEL-1497796 BH2 binding can lead to eNOS uncoupling IEA Caenorhabditis elegans 57692 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 57692 R-CEL-1655453 https://reactome.org/PathwayBrowser/#/R-CEL-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Caenorhabditis elegans 57692 R-CEL-169260 https://reactome.org/PathwayBrowser/#/R-CEL-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Caenorhabditis elegans 57692 R-CEL-169270 https://reactome.org/PathwayBrowser/#/R-CEL-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Caenorhabditis elegans 57692 R-CEL-174374 https://reactome.org/PathwayBrowser/#/R-CEL-174374 MTR transfers CH3 from MeCbl to HCYS IEA Caenorhabditis elegans 57692 R-CEL-188467 https://reactome.org/PathwayBrowser/#/R-CEL-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Caenorhabditis elegans 57692 R-CEL-192335 https://reactome.org/PathwayBrowser/#/R-CEL-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Caenorhabditis elegans 57692 R-CEL-193369 https://reactome.org/PathwayBrowser/#/R-CEL-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Caenorhabditis elegans 57692 R-CEL-196929 https://reactome.org/PathwayBrowser/#/R-CEL-196929 FLAD1 phosphorylates FMN IEA Caenorhabditis elegans 57692 R-CEL-196955 https://reactome.org/PathwayBrowser/#/R-CEL-196955 2xENPP1 hydrolyzes FAD to FMN IEA Caenorhabditis elegans 57692 R-CEL-202111 https://reactome.org/PathwayBrowser/#/R-CEL-202111 AKT1 phosphorylates eNOS IEA Caenorhabditis elegans 57692 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 57692 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 57692 R-CEL-204169 https://reactome.org/PathwayBrowser/#/R-CEL-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Caenorhabditis elegans 57692 R-CEL-2066787 https://reactome.org/PathwayBrowser/#/R-CEL-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Caenorhabditis elegans 57692 R-CEL-2162186 https://reactome.org/PathwayBrowser/#/R-CEL-2162186 COQ3 methylates DeMQ10H2 IEA Caenorhabditis elegans 57692 R-CEL-2162188 https://reactome.org/PathwayBrowser/#/R-CEL-2162188 COQ5 methylates MDMQ10H2 IEA Caenorhabditis elegans 57692 R-CEL-2162193 https://reactome.org/PathwayBrowser/#/R-CEL-2162193 COQ3 methylates DHDB IEA Caenorhabditis elegans 57692 R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 57692 R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 57692 R-CEL-2395512 https://reactome.org/PathwayBrowser/#/R-CEL-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Caenorhabditis elegans 57692 R-CEL-2395517 https://reactome.org/PathwayBrowser/#/R-CEL-2395517 NADPH transfers electrons to FDXR IEA Caenorhabditis elegans 57692 R-CEL-3149518 https://reactome.org/PathwayBrowser/#/R-CEL-3149518 MTRR reduces cob(II)alamin to meCbl IEA Caenorhabditis elegans 57692 R-CEL-3149539 https://reactome.org/PathwayBrowser/#/R-CEL-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Caenorhabditis elegans 57692 R-CEL-3159253 https://reactome.org/PathwayBrowser/#/R-CEL-3159253 MMAB adenosylates cob(I)alamin IEA Caenorhabditis elegans 57692 R-CEL-3165230 https://reactome.org/PathwayBrowser/#/R-CEL-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Caenorhabditis elegans 57692 R-CEL-3204311 https://reactome.org/PathwayBrowser/#/R-CEL-3204311 AOX1 oxidises PXL to PDXate IEA Caenorhabditis elegans 57692 R-CEL-3204318 https://reactome.org/PathwayBrowser/#/R-CEL-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Caenorhabditis elegans 57692 R-CEL-3323050 https://reactome.org/PathwayBrowser/#/R-CEL-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Caenorhabditis elegans 57692 R-CEL-3323079 https://reactome.org/PathwayBrowser/#/R-CEL-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 57692 R-CEL-389821 https://reactome.org/PathwayBrowser/#/R-CEL-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Caenorhabditis elegans 57692 R-CEL-389889 https://reactome.org/PathwayBrowser/#/R-CEL-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Caenorhabditis elegans 57692 R-CEL-389891 https://reactome.org/PathwayBrowser/#/R-CEL-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Caenorhabditis elegans 57692 R-CEL-390256 https://reactome.org/PathwayBrowser/#/R-CEL-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Caenorhabditis elegans 57692 R-CEL-390427 https://reactome.org/PathwayBrowser/#/R-CEL-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Caenorhabditis elegans 57692 R-CEL-5263614 https://reactome.org/PathwayBrowser/#/R-CEL-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Caenorhabditis elegans 57692 R-CEL-5263616 https://reactome.org/PathwayBrowser/#/R-CEL-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Caenorhabditis elegans 57692 R-CEL-5694018 https://reactome.org/PathwayBrowser/#/R-CEL-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Caenorhabditis elegans 57692 R-CEL-5695980 https://reactome.org/PathwayBrowser/#/R-CEL-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Caenorhabditis elegans 57692 R-CEL-6784224 https://reactome.org/PathwayBrowser/#/R-CEL-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Caenorhabditis elegans 57692 R-CEL-6797653 https://reactome.org/PathwayBrowser/#/R-CEL-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Caenorhabditis elegans 57692 R-CEL-6799178 https://reactome.org/PathwayBrowser/#/R-CEL-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Caenorhabditis elegans 57692 R-CEL-6799191 https://reactome.org/PathwayBrowser/#/R-CEL-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Caenorhabditis elegans 57692 R-CEL-6799197 https://reactome.org/PathwayBrowser/#/R-CEL-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Caenorhabditis elegans 57692 R-CEL-6799203 https://reactome.org/PathwayBrowser/#/R-CEL-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Caenorhabditis elegans 57692 R-CEL-6800868 https://reactome.org/PathwayBrowser/#/R-CEL-6800868 NDUF subunits bind to form the IP subcomplex IEA Caenorhabditis elegans 57692 R-CEL-6810076 https://reactome.org/PathwayBrowser/#/R-CEL-6810076 DDO oxidizes D-Asp to OA IEA Caenorhabditis elegans 57692 R-CEL-70670 https://reactome.org/PathwayBrowser/#/R-CEL-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Caenorhabditis elegans 57692 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 57692 R-CEL-70745 https://reactome.org/PathwayBrowser/#/R-CEL-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Caenorhabditis elegans 57692 R-CEL-70800 https://reactome.org/PathwayBrowser/#/R-CEL-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Caenorhabditis elegans 57692 R-CEL-70859 https://reactome.org/PathwayBrowser/#/R-CEL-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Caenorhabditis elegans 57692 R-CEL-71037 https://reactome.org/PathwayBrowser/#/R-CEL-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 57692 R-CEL-71046 https://reactome.org/PathwayBrowser/#/R-CEL-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Caenorhabditis elegans 57692 R-CEL-71401 https://reactome.org/PathwayBrowser/#/R-CEL-71401 OGDH dimer decarboxylates 2-OG IEA Caenorhabditis elegans 57692 R-CEL-71682 https://reactome.org/PathwayBrowser/#/R-CEL-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 57692 R-CEL-73585 https://reactome.org/PathwayBrowser/#/R-CEL-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Caenorhabditis elegans 57692 R-CEL-73616 https://reactome.org/PathwayBrowser/#/R-CEL-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Caenorhabditis elegans 57692 R-CEL-73646 https://reactome.org/PathwayBrowser/#/R-CEL-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Caenorhabditis elegans 57692 R-CEL-74247 https://reactome.org/PathwayBrowser/#/R-CEL-74247 XDH oxidizes hypoxanthine to form xanthine IEA Caenorhabditis elegans 57692 R-CEL-74258 https://reactome.org/PathwayBrowser/#/R-CEL-74258 XDH oxidizes xanthine to form urate IEA Caenorhabditis elegans 57692 R-CEL-75879 https://reactome.org/PathwayBrowser/#/R-CEL-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Caenorhabditis elegans 57692 R-CEL-77299 https://reactome.org/PathwayBrowser/#/R-CEL-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 57692 R-CEL-77338 https://reactome.org/PathwayBrowser/#/R-CEL-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 57692 R-CEL-77345 https://reactome.org/PathwayBrowser/#/R-CEL-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 57692 R-CEL-880007 https://reactome.org/PathwayBrowser/#/R-CEL-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Caenorhabditis elegans 57692 R-CEL-880050 https://reactome.org/PathwayBrowser/#/R-CEL-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Caenorhabditis elegans 57692 R-CEL-8865107 https://reactome.org/PathwayBrowser/#/R-CEL-8865107 MICAL1 produces NADP+, H2O2 IEA Caenorhabditis elegans 57692 R-CEL-8955817 https://reactome.org/PathwayBrowser/#/R-CEL-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Caenorhabditis elegans 57692 R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 57692 R-CEL-9727349 https://reactome.org/PathwayBrowser/#/R-CEL-9727349 XDH dehydrogenates xanthine to form urate IEA Caenorhabditis elegans 57692 R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 57692 R-CEL-9853499 https://reactome.org/PathwayBrowser/#/R-CEL-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 57692 R-CEL-9853512 https://reactome.org/PathwayBrowser/#/R-CEL-9853512 DLST transfers succinyl to CoA IEA Caenorhabditis elegans 57692 R-CEL-9854672 https://reactome.org/PathwayBrowser/#/R-CEL-9854672 FAD attaches to SDHA IEA Caenorhabditis elegans 57692 R-CEL-9861616 https://reactome.org/PathwayBrowser/#/R-CEL-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 57692 R-CEL-9861667 https://reactome.org/PathwayBrowser/#/R-CEL-9861667 DLAT trimer transfers acetyl to CoA IEA Caenorhabditis elegans 57692 R-CEL-9861734 https://reactome.org/PathwayBrowser/#/R-CEL-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Caenorhabditis elegans 57692 R-CFA-109341 https://reactome.org/PathwayBrowser/#/R-CFA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Canis familiaris 57692 R-CFA-1222376 https://reactome.org/PathwayBrowser/#/R-CFA-1222376 NOX2 generates superoxide from oxygen IEA Canis familiaris 57692 R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 57692 R-CFA-141186 https://reactome.org/PathwayBrowser/#/R-CFA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Canis familiaris 57692 R-CFA-141200 https://reactome.org/PathwayBrowser/#/R-CFA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Canis familiaris 57692 R-CFA-141202 https://reactome.org/PathwayBrowser/#/R-CFA-141202 MAOB:FAD oxidatively deaminates TYR IEA Canis familiaris 57692 R-CFA-141348 https://reactome.org/PathwayBrowser/#/R-CFA-141348 PAO:FAD oxidises NASPM to PTCN IEA Canis familiaris 57692 R-CFA-141351 https://reactome.org/PathwayBrowser/#/R-CFA-141351 PAOX:FAD oxidises NASPN to SPM IEA Canis familiaris 57692 R-CFA-163217 https://reactome.org/PathwayBrowser/#/R-CFA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Canis familiaris 57692 R-CFA-1655453 https://reactome.org/PathwayBrowser/#/R-CFA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Canis familiaris 57692 R-CFA-169260 https://reactome.org/PathwayBrowser/#/R-CFA-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Canis familiaris 57692 R-CFA-169270 https://reactome.org/PathwayBrowser/#/R-CFA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Canis familiaris 57692 R-CFA-174374 https://reactome.org/PathwayBrowser/#/R-CFA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Canis familiaris 57692 R-CFA-188467 https://reactome.org/PathwayBrowser/#/R-CFA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Canis familiaris 57692 R-CFA-189423 https://reactome.org/PathwayBrowser/#/R-CFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Canis familiaris 57692 R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 57692 R-CFA-192335 https://reactome.org/PathwayBrowser/#/R-CFA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Canis familiaris 57692 R-CFA-193369 https://reactome.org/PathwayBrowser/#/R-CFA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Canis familiaris 57692 R-CFA-196929 https://reactome.org/PathwayBrowser/#/R-CFA-196929 FLAD1 phosphorylates FMN IEA Canis familiaris 57692 R-CFA-196955 https://reactome.org/PathwayBrowser/#/R-CFA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Canis familiaris 57692 R-CFA-198824 https://reactome.org/PathwayBrowser/#/R-CFA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Canis familiaris 57692 R-CFA-203565 https://reactome.org/PathwayBrowser/#/R-CFA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Canis familiaris 57692 R-CFA-203625 https://reactome.org/PathwayBrowser/#/R-CFA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Canis familiaris 57692 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 57692 R-CFA-204169 https://reactome.org/PathwayBrowser/#/R-CFA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Canis familiaris 57692 R-CFA-2066787 https://reactome.org/PathwayBrowser/#/R-CFA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Canis familiaris 57692 R-CFA-2160492 https://reactome.org/PathwayBrowser/#/R-CFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Canis familiaris 57692 R-CFA-2162186 https://reactome.org/PathwayBrowser/#/R-CFA-2162186 COQ3 methylates DeMQ10H2 IEA Canis familiaris 57692 R-CFA-2162188 https://reactome.org/PathwayBrowser/#/R-CFA-2162188 COQ5 methylates MDMQ10H2 IEA Canis familiaris 57692 R-CFA-2162193 https://reactome.org/PathwayBrowser/#/R-CFA-2162193 COQ3 methylates DHDB IEA Canis familiaris 57692 R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 57692 R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 57692 R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 57692 R-CFA-2395512 https://reactome.org/PathwayBrowser/#/R-CFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Canis familiaris 57692 R-CFA-2395517 https://reactome.org/PathwayBrowser/#/R-CFA-2395517 NADPH transfers electrons to FDXR IEA Canis familiaris 57692 R-CFA-3149518 https://reactome.org/PathwayBrowser/#/R-CFA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Canis familiaris 57692 R-CFA-3149539 https://reactome.org/PathwayBrowser/#/R-CFA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Canis familiaris 57692 R-CFA-3159253 https://reactome.org/PathwayBrowser/#/R-CFA-3159253 MMAB adenosylates cob(I)alamin IEA Canis familiaris 57692 R-CFA-3165230 https://reactome.org/PathwayBrowser/#/R-CFA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Canis familiaris 57692 R-CFA-3204318 https://reactome.org/PathwayBrowser/#/R-CFA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Canis familiaris 57692 R-CFA-3323079 https://reactome.org/PathwayBrowser/#/R-CFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 57692 R-CFA-374909 https://reactome.org/PathwayBrowser/#/R-CFA-374909 Catabolism of Noradrenaline IEA Canis familiaris 57692 R-CFA-379382 https://reactome.org/PathwayBrowser/#/R-CFA-379382 MAOA:FAD deaminates DA to DOPAC IEA Canis familiaris 57692 R-CFA-379395 https://reactome.org/PathwayBrowser/#/R-CFA-379395 MAOA:FAD deaminates 3MT to HVA IEA Canis familiaris 57692 R-CFA-389821 https://reactome.org/PathwayBrowser/#/R-CFA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Canis familiaris 57692 R-CFA-389889 https://reactome.org/PathwayBrowser/#/R-CFA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Canis familiaris 57692 R-CFA-389891 https://reactome.org/PathwayBrowser/#/R-CFA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Canis familiaris 57692 R-CFA-390256 https://reactome.org/PathwayBrowser/#/R-CFA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Canis familiaris 57692 R-CFA-390427 https://reactome.org/PathwayBrowser/#/R-CFA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Canis familiaris 57692 R-CFA-5218827 https://reactome.org/PathwayBrowser/#/R-CFA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Canis familiaris 57692 R-CFA-5218841 https://reactome.org/PathwayBrowser/#/R-CFA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Canis familiaris 57692 R-CFA-5693148 https://reactome.org/PathwayBrowser/#/R-CFA-5693148 BCKDK phosphorylates BCKDH IEA Canis familiaris 57692 R-CFA-5693153 https://reactome.org/PathwayBrowser/#/R-CFA-5693153 PPM1K dephosphorylates p-BCKDH IEA Canis familiaris 57692 R-CFA-5694018 https://reactome.org/PathwayBrowser/#/R-CFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Canis familiaris 57692 R-CFA-5695989 https://reactome.org/PathwayBrowser/#/R-CFA-5695989 ACAD11 dehydrogenates BH-CoA IEA Canis familiaris 57692 R-CFA-6784224 https://reactome.org/PathwayBrowser/#/R-CFA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Canis familiaris 57692 R-CFA-6797653 https://reactome.org/PathwayBrowser/#/R-CFA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Canis familiaris 57692 R-CFA-6797913 https://reactome.org/PathwayBrowser/#/R-CFA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Canis familiaris 57692 R-CFA-6799178 https://reactome.org/PathwayBrowser/#/R-CFA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Canis familiaris 57692 R-CFA-6799179 https://reactome.org/PathwayBrowser/#/R-CFA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Canis familiaris 57692 R-CFA-6799196 https://reactome.org/PathwayBrowser/#/R-CFA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Canis familiaris 57692 R-CFA-6799203 https://reactome.org/PathwayBrowser/#/R-CFA-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Canis familiaris 57692 R-CFA-6800868 https://reactome.org/PathwayBrowser/#/R-CFA-6800868 NDUF subunits bind to form the IP subcomplex IEA Canis familiaris 57692 R-CFA-6810076 https://reactome.org/PathwayBrowser/#/R-CFA-6810076 DDO oxidizes D-Asp to OA IEA Canis familiaris 57692 R-CFA-70670 https://reactome.org/PathwayBrowser/#/R-CFA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Canis familiaris 57692 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 57692 R-CFA-70745 https://reactome.org/PathwayBrowser/#/R-CFA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Canis familiaris 57692 R-CFA-70800 https://reactome.org/PathwayBrowser/#/R-CFA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Canis familiaris 57692 R-CFA-70859 https://reactome.org/PathwayBrowser/#/R-CFA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Canis familiaris 57692 R-CFA-71037 https://reactome.org/PathwayBrowser/#/R-CFA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Canis familiaris 57692 R-CFA-71046 https://reactome.org/PathwayBrowser/#/R-CFA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Canis familiaris 57692 R-CFA-71401 https://reactome.org/PathwayBrowser/#/R-CFA-71401 OGDH dimer decarboxylates 2-OG IEA Canis familiaris 57692 R-CFA-71682 https://reactome.org/PathwayBrowser/#/R-CFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 57692 R-CFA-73585 https://reactome.org/PathwayBrowser/#/R-CFA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Canis familiaris 57692 R-CFA-73616 https://reactome.org/PathwayBrowser/#/R-CFA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Canis familiaris 57692 R-CFA-74247 https://reactome.org/PathwayBrowser/#/R-CFA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Canis familiaris 57692 R-CFA-74258 https://reactome.org/PathwayBrowser/#/R-CFA-74258 XDH oxidizes xanthine to form urate IEA Canis familiaris 57692 R-CFA-75879 https://reactome.org/PathwayBrowser/#/R-CFA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Canis familiaris 57692 R-CFA-77263 https://reactome.org/PathwayBrowser/#/R-CFA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Canis familiaris 57692 R-CFA-77274 https://reactome.org/PathwayBrowser/#/R-CFA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Canis familiaris 57692 R-CFA-77299 https://reactome.org/PathwayBrowser/#/R-CFA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Canis familiaris 57692 R-CFA-77319 https://reactome.org/PathwayBrowser/#/R-CFA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Canis familiaris 57692 R-CFA-77327 https://reactome.org/PathwayBrowser/#/R-CFA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Canis familiaris 57692 R-CFA-77338 https://reactome.org/PathwayBrowser/#/R-CFA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Canis familiaris 57692 R-CFA-77345 https://reactome.org/PathwayBrowser/#/R-CFA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Canis familiaris 57692 R-CFA-880007 https://reactome.org/PathwayBrowser/#/R-CFA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Canis familiaris 57692 R-CFA-880050 https://reactome.org/PathwayBrowser/#/R-CFA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Canis familiaris 57692 R-CFA-8936519 https://reactome.org/PathwayBrowser/#/R-CFA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Canis familiaris 57692 R-CFA-8955817 https://reactome.org/PathwayBrowser/#/R-CFA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Canis familiaris 57692 R-CFA-8956458 https://reactome.org/PathwayBrowser/#/R-CFA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Canis familiaris 57692 R-CFA-9013145 https://reactome.org/PathwayBrowser/#/R-CFA-9013145 RAC1 binds effectors at the plasma membrane IEA Canis familiaris 57692 R-CFA-9018808 https://reactome.org/PathwayBrowser/#/R-CFA-9018808 RAC3 binds effectors at the plasma membrane IEA Canis familiaris 57692 R-CFA-917811 https://reactome.org/PathwayBrowser/#/R-CFA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Canis familiaris 57692 R-CFA-9677917 https://reactome.org/PathwayBrowser/#/R-CFA-9677917 MAOA inhibitors bind MAOA:FAD IEA Canis familiaris 57692 R-CFA-9677929 https://reactome.org/PathwayBrowser/#/R-CFA-9677929 MAOB inhibitors bind MAOB:FAD IEA Canis familiaris 57692 R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 57692 R-CFA-9727349 https://reactome.org/PathwayBrowser/#/R-CFA-9727349 XDH dehydrogenates xanthine to form urate IEA Canis familiaris 57692 R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 57692 R-CFA-9853499 https://reactome.org/PathwayBrowser/#/R-CFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 57692 R-CFA-9853512 https://reactome.org/PathwayBrowser/#/R-CFA-9853512 DLST transfers succinyl to CoA IEA Canis familiaris 57692 R-CFA-9854672 https://reactome.org/PathwayBrowser/#/R-CFA-9854672 FAD attaches to SDHA IEA Canis familiaris 57692 R-CFA-9861616 https://reactome.org/PathwayBrowser/#/R-CFA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 57692 R-CFA-9861667 https://reactome.org/PathwayBrowser/#/R-CFA-9861667 DLAT trimer transfers acetyl to CoA IEA Canis familiaris 57692 R-CFA-9861734 https://reactome.org/PathwayBrowser/#/R-CFA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Canis familiaris 57692 R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 57692 R-DDI-141186 https://reactome.org/PathwayBrowser/#/R-DDI-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Dictyostelium discoideum 57692 R-DDI-141200 https://reactome.org/PathwayBrowser/#/R-DDI-141200 MAOB:FAD oxidatively deaminates of PEA IEA Dictyostelium discoideum 57692 R-DDI-141202 https://reactome.org/PathwayBrowser/#/R-DDI-141202 MAOB:FAD oxidatively deaminates TYR IEA Dictyostelium discoideum 57692 R-DDI-1497784 https://reactome.org/PathwayBrowser/#/R-DDI-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Dictyostelium discoideum 57692 R-DDI-1497796 https://reactome.org/PathwayBrowser/#/R-DDI-1497796 BH2 binding can lead to eNOS uncoupling IEA Dictyostelium discoideum 57692 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 57692 R-DDI-1655453 https://reactome.org/PathwayBrowser/#/R-DDI-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Dictyostelium discoideum 57692 R-DDI-169260 https://reactome.org/PathwayBrowser/#/R-DDI-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Dictyostelium discoideum 57692 R-DDI-169270 https://reactome.org/PathwayBrowser/#/R-DDI-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Dictyostelium discoideum 57692 R-DDI-174374 https://reactome.org/PathwayBrowser/#/R-DDI-174374 MTR transfers CH3 from MeCbl to HCYS IEA Dictyostelium discoideum 57692 R-DDI-188467 https://reactome.org/PathwayBrowser/#/R-DDI-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Dictyostelium discoideum 57692 R-DDI-189423 https://reactome.org/PathwayBrowser/#/R-DDI-189423 PPO oxidises PPGEN9 to PRIN9 IEA Dictyostelium discoideum 57692 R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 57692 R-DDI-192335 https://reactome.org/PathwayBrowser/#/R-DDI-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Dictyostelium discoideum 57692 R-DDI-193369 https://reactome.org/PathwayBrowser/#/R-DDI-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Dictyostelium discoideum 57692 R-DDI-196929 https://reactome.org/PathwayBrowser/#/R-DDI-196929 FLAD1 phosphorylates FMN IEA Dictyostelium discoideum 57692 R-DDI-196955 https://reactome.org/PathwayBrowser/#/R-DDI-196955 2xENPP1 hydrolyzes FAD to FMN IEA Dictyostelium discoideum 57692 R-DDI-198824 https://reactome.org/PathwayBrowser/#/R-DDI-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Dictyostelium discoideum 57692 R-DDI-202111 https://reactome.org/PathwayBrowser/#/R-DDI-202111 AKT1 phosphorylates eNOS IEA Dictyostelium discoideum 57692 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 57692 R-DDI-202132 https://reactome.org/PathwayBrowser/#/R-DDI-202132 depalmitoylated eNOS translocates from plasma membrane IEA Dictyostelium discoideum 57692 R-DDI-202137 https://reactome.org/PathwayBrowser/#/R-DDI-202137 AKT1 binds eNOS complex via HSP90 IEA Dictyostelium discoideum 57692 R-DDI-203553 https://reactome.org/PathwayBrowser/#/R-DDI-203553 eNOS binds NOSIP IEA Dictyostelium discoideum 57692 R-DDI-203613 https://reactome.org/PathwayBrowser/#/R-DDI-203613 depalmitoylation of eNOS IEA Dictyostelium discoideum 57692 R-DDI-203680 https://reactome.org/PathwayBrowser/#/R-DDI-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Dictyostelium discoideum 57692 R-DDI-203700 https://reactome.org/PathwayBrowser/#/R-DDI-203700 eNOS translocation from Golgi to Caveolae IEA Dictyostelium discoideum 57692 R-DDI-2066787 https://reactome.org/PathwayBrowser/#/R-DDI-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Dictyostelium discoideum 57692 R-DDI-2160492 https://reactome.org/PathwayBrowser/#/R-DDI-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Dictyostelium discoideum 57692 R-DDI-2162186 https://reactome.org/PathwayBrowser/#/R-DDI-2162186 COQ3 methylates DeMQ10H2 IEA Dictyostelium discoideum 57692 R-DDI-2162188 https://reactome.org/PathwayBrowser/#/R-DDI-2162188 COQ5 methylates MDMQ10H2 IEA Dictyostelium discoideum 57692 R-DDI-2162193 https://reactome.org/PathwayBrowser/#/R-DDI-2162193 COQ3 methylates DHDB IEA Dictyostelium discoideum 57692 R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 57692 R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 57692 R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 57692 R-DDI-2395512 https://reactome.org/PathwayBrowser/#/R-DDI-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Dictyostelium discoideum 57692 R-DDI-2395517 https://reactome.org/PathwayBrowser/#/R-DDI-2395517 NADPH transfers electrons to FDXR IEA Dictyostelium discoideum 57692 R-DDI-3149518 https://reactome.org/PathwayBrowser/#/R-DDI-3149518 MTRR reduces cob(II)alamin to meCbl IEA Dictyostelium discoideum 57692 R-DDI-3149539 https://reactome.org/PathwayBrowser/#/R-DDI-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Dictyostelium discoideum 57692 R-DDI-3159253 https://reactome.org/PathwayBrowser/#/R-DDI-3159253 MMAB adenosylates cob(I)alamin IEA Dictyostelium discoideum 57692 R-DDI-3204311 https://reactome.org/PathwayBrowser/#/R-DDI-3204311 AOX1 oxidises PXL to PDXate IEA Dictyostelium discoideum 57692 R-DDI-3323079 https://reactome.org/PathwayBrowser/#/R-DDI-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 57692 R-DDI-374909 https://reactome.org/PathwayBrowser/#/R-DDI-374909 Catabolism of Noradrenaline IEA Dictyostelium discoideum 57692 R-DDI-379382 https://reactome.org/PathwayBrowser/#/R-DDI-379382 MAOA:FAD deaminates DA to DOPAC IEA Dictyostelium discoideum 57692 R-DDI-379395 https://reactome.org/PathwayBrowser/#/R-DDI-379395 MAOA:FAD deaminates 3MT to HVA IEA Dictyostelium discoideum 57692 R-DDI-389821 https://reactome.org/PathwayBrowser/#/R-DDI-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Dictyostelium discoideum 57692 R-DDI-389889 https://reactome.org/PathwayBrowser/#/R-DDI-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Dictyostelium discoideum 57692 R-DDI-389891 https://reactome.org/PathwayBrowser/#/R-DDI-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Dictyostelium discoideum 57692 R-DDI-390256 https://reactome.org/PathwayBrowser/#/R-DDI-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Dictyostelium discoideum 57692 R-DDI-5694018 https://reactome.org/PathwayBrowser/#/R-DDI-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Dictyostelium discoideum 57692 R-DDI-6784224 https://reactome.org/PathwayBrowser/#/R-DDI-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Dictyostelium discoideum 57692 R-DDI-6800868 https://reactome.org/PathwayBrowser/#/R-DDI-6800868 NDUF subunits bind to form the IP subcomplex IEA Dictyostelium discoideum 57692 R-DDI-6810076 https://reactome.org/PathwayBrowser/#/R-DDI-6810076 DDO oxidizes D-Asp to OA IEA Dictyostelium discoideum 57692 R-DDI-70670 https://reactome.org/PathwayBrowser/#/R-DDI-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Dictyostelium discoideum 57692 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 57692 R-DDI-70745 https://reactome.org/PathwayBrowser/#/R-DDI-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Dictyostelium discoideum 57692 R-DDI-70800 https://reactome.org/PathwayBrowser/#/R-DDI-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Dictyostelium discoideum 57692 R-DDI-70859 https://reactome.org/PathwayBrowser/#/R-DDI-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Dictyostelium discoideum 57692 R-DDI-71037 https://reactome.org/PathwayBrowser/#/R-DDI-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 57692 R-DDI-71046 https://reactome.org/PathwayBrowser/#/R-DDI-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Dictyostelium discoideum 57692 R-DDI-71401 https://reactome.org/PathwayBrowser/#/R-DDI-71401 OGDH dimer decarboxylates 2-OG IEA Dictyostelium discoideum 57692 R-DDI-71682 https://reactome.org/PathwayBrowser/#/R-DDI-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 57692 R-DDI-73585 https://reactome.org/PathwayBrowser/#/R-DDI-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Dictyostelium discoideum 57692 R-DDI-73616 https://reactome.org/PathwayBrowser/#/R-DDI-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Dictyostelium discoideum 57692 R-DDI-74247 https://reactome.org/PathwayBrowser/#/R-DDI-74247 XDH oxidizes hypoxanthine to form xanthine IEA Dictyostelium discoideum 57692 R-DDI-74258 https://reactome.org/PathwayBrowser/#/R-DDI-74258 XDH oxidizes xanthine to form urate IEA Dictyostelium discoideum 57692 R-DDI-880007 https://reactome.org/PathwayBrowser/#/R-DDI-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Dictyostelium discoideum 57692 R-DDI-880050 https://reactome.org/PathwayBrowser/#/R-DDI-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Dictyostelium discoideum 57692 R-DDI-8865107 https://reactome.org/PathwayBrowser/#/R-DDI-8865107 MICAL1 produces NADP+, H2O2 IEA Dictyostelium discoideum 57692 R-DDI-8955817 https://reactome.org/PathwayBrowser/#/R-DDI-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Dictyostelium discoideum 57692 R-DDI-9677917 https://reactome.org/PathwayBrowser/#/R-DDI-9677917 MAOA inhibitors bind MAOA:FAD IEA Dictyostelium discoideum 57692 R-DDI-9677929 https://reactome.org/PathwayBrowser/#/R-DDI-9677929 MAOB inhibitors bind MAOB:FAD IEA Dictyostelium discoideum 57692 R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 57692 R-DDI-9727349 https://reactome.org/PathwayBrowser/#/R-DDI-9727349 XDH dehydrogenates xanthine to form urate IEA Dictyostelium discoideum 57692 R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 57692 R-DDI-9853499 https://reactome.org/PathwayBrowser/#/R-DDI-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 57692 R-DDI-9853512 https://reactome.org/PathwayBrowser/#/R-DDI-9853512 DLST transfers succinyl to CoA IEA Dictyostelium discoideum 57692 R-DDI-9854672 https://reactome.org/PathwayBrowser/#/R-DDI-9854672 FAD attaches to SDHA IEA Dictyostelium discoideum 57692 R-DDI-9861616 https://reactome.org/PathwayBrowser/#/R-DDI-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 57692 R-DDI-9861667 https://reactome.org/PathwayBrowser/#/R-DDI-9861667 DLAT trimer transfers acetyl to CoA IEA Dictyostelium discoideum 57692 R-DDI-9861734 https://reactome.org/PathwayBrowser/#/R-DDI-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Dictyostelium discoideum 57692 R-DME-109341 https://reactome.org/PathwayBrowser/#/R-DME-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Drosophila melanogaster 57692 R-DME-141348 https://reactome.org/PathwayBrowser/#/R-DME-141348 PAO:FAD oxidises NASPM to PTCN IEA Drosophila melanogaster 57692 R-DME-141351 https://reactome.org/PathwayBrowser/#/R-DME-141351 PAOX:FAD oxidises NASPN to SPM IEA Drosophila melanogaster 57692 R-DME-1497784 https://reactome.org/PathwayBrowser/#/R-DME-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Drosophila melanogaster 57692 R-DME-1497796 https://reactome.org/PathwayBrowser/#/R-DME-1497796 BH2 binding can lead to eNOS uncoupling IEA Drosophila melanogaster 57692 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 57692 R-DME-163217 https://reactome.org/PathwayBrowser/#/R-DME-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Drosophila melanogaster 57692 R-DME-169260 https://reactome.org/PathwayBrowser/#/R-DME-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Drosophila melanogaster 57692 R-DME-169270 https://reactome.org/PathwayBrowser/#/R-DME-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Drosophila melanogaster 57692 R-DME-188467 https://reactome.org/PathwayBrowser/#/R-DME-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Drosophila melanogaster 57692 R-DME-189423 https://reactome.org/PathwayBrowser/#/R-DME-189423 PPO oxidises PPGEN9 to PRIN9 IEA Drosophila melanogaster 57692 R-DME-192335 https://reactome.org/PathwayBrowser/#/R-DME-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Drosophila melanogaster 57692 R-DME-193369 https://reactome.org/PathwayBrowser/#/R-DME-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Drosophila melanogaster 57692 R-DME-196929 https://reactome.org/PathwayBrowser/#/R-DME-196929 FLAD1 phosphorylates FMN IEA Drosophila melanogaster 57692 R-DME-198824 https://reactome.org/PathwayBrowser/#/R-DME-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Drosophila melanogaster 57692 R-DME-202111 https://reactome.org/PathwayBrowser/#/R-DME-202111 AKT1 phosphorylates eNOS IEA Drosophila melanogaster 57692 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 57692 R-DME-202132 https://reactome.org/PathwayBrowser/#/R-DME-202132 depalmitoylated eNOS translocates from plasma membrane IEA Drosophila melanogaster 57692 R-DME-202137 https://reactome.org/PathwayBrowser/#/R-DME-202137 AKT1 binds eNOS complex via HSP90 IEA Drosophila melanogaster 57692 R-DME-203553 https://reactome.org/PathwayBrowser/#/R-DME-203553 eNOS binds NOSIP IEA Drosophila melanogaster 57692 R-DME-203613 https://reactome.org/PathwayBrowser/#/R-DME-203613 depalmitoylation of eNOS IEA Drosophila melanogaster 57692 R-DME-203680 https://reactome.org/PathwayBrowser/#/R-DME-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Drosophila melanogaster 57692 R-DME-203700 https://reactome.org/PathwayBrowser/#/R-DME-203700 eNOS translocation from Golgi to Caveolae IEA Drosophila melanogaster 57692 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 57692 R-DME-204169 https://reactome.org/PathwayBrowser/#/R-DME-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Drosophila melanogaster 57692 R-DME-2066787 https://reactome.org/PathwayBrowser/#/R-DME-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Drosophila melanogaster 57692 R-DME-2162186 https://reactome.org/PathwayBrowser/#/R-DME-2162186 COQ3 methylates DeMQ10H2 IEA Drosophila melanogaster 57692 R-DME-2162188 https://reactome.org/PathwayBrowser/#/R-DME-2162188 COQ5 methylates MDMQ10H2 IEA Drosophila melanogaster 57692 R-DME-2162193 https://reactome.org/PathwayBrowser/#/R-DME-2162193 COQ3 methylates DHDB IEA Drosophila melanogaster 57692 R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 57692 R-DME-2395512 https://reactome.org/PathwayBrowser/#/R-DME-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Drosophila melanogaster 57692 R-DME-2395517 https://reactome.org/PathwayBrowser/#/R-DME-2395517 NADPH transfers electrons to FDXR IEA Drosophila melanogaster 57692 R-DME-3165230 https://reactome.org/PathwayBrowser/#/R-DME-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Drosophila melanogaster 57692 R-DME-3204311 https://reactome.org/PathwayBrowser/#/R-DME-3204311 AOX1 oxidises PXL to PDXate IEA Drosophila melanogaster 57692 R-DME-3323050 https://reactome.org/PathwayBrowser/#/R-DME-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Drosophila melanogaster 57692 R-DME-389821 https://reactome.org/PathwayBrowser/#/R-DME-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Drosophila melanogaster 57692 R-DME-389889 https://reactome.org/PathwayBrowser/#/R-DME-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Drosophila melanogaster 57692 R-DME-389891 https://reactome.org/PathwayBrowser/#/R-DME-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Drosophila melanogaster 57692 R-DME-390256 https://reactome.org/PathwayBrowser/#/R-DME-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Drosophila melanogaster 57692 R-DME-390427 https://reactome.org/PathwayBrowser/#/R-DME-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Drosophila melanogaster 57692 R-DME-5694018 https://reactome.org/PathwayBrowser/#/R-DME-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Drosophila melanogaster 57692 R-DME-6784224 https://reactome.org/PathwayBrowser/#/R-DME-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Drosophila melanogaster 57692 R-DME-6797913 https://reactome.org/PathwayBrowser/#/R-DME-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Drosophila melanogaster 57692 R-DME-6799178 https://reactome.org/PathwayBrowser/#/R-DME-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Drosophila melanogaster 57692 R-DME-6799191 https://reactome.org/PathwayBrowser/#/R-DME-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Drosophila melanogaster 57692 R-DME-6799196 https://reactome.org/PathwayBrowser/#/R-DME-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Drosophila melanogaster 57692 R-DME-6799197 https://reactome.org/PathwayBrowser/#/R-DME-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Drosophila melanogaster 57692 R-DME-6799202 https://reactome.org/PathwayBrowser/#/R-DME-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Drosophila melanogaster 57692 R-DME-6799203 https://reactome.org/PathwayBrowser/#/R-DME-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Drosophila melanogaster 57692 R-DME-6800868 https://reactome.org/PathwayBrowser/#/R-DME-6800868 NDUF subunits bind to form the IP subcomplex IEA Drosophila melanogaster 57692 R-DME-6810076 https://reactome.org/PathwayBrowser/#/R-DME-6810076 DDO oxidizes D-Asp to OA IEA Drosophila melanogaster 57692 R-DME-70670 https://reactome.org/PathwayBrowser/#/R-DME-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Drosophila melanogaster 57692 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 57692 R-DME-70745 https://reactome.org/PathwayBrowser/#/R-DME-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Drosophila melanogaster 57692 R-DME-70800 https://reactome.org/PathwayBrowser/#/R-DME-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Drosophila melanogaster 57692 R-DME-71037 https://reactome.org/PathwayBrowser/#/R-DME-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 57692 R-DME-71046 https://reactome.org/PathwayBrowser/#/R-DME-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Drosophila melanogaster 57692 R-DME-71401 https://reactome.org/PathwayBrowser/#/R-DME-71401 OGDH dimer decarboxylates 2-OG IEA Drosophila melanogaster 57692 R-DME-73585 https://reactome.org/PathwayBrowser/#/R-DME-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Drosophila melanogaster 57692 R-DME-73616 https://reactome.org/PathwayBrowser/#/R-DME-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Drosophila melanogaster 57692 R-DME-74247 https://reactome.org/PathwayBrowser/#/R-DME-74247 XDH oxidizes hypoxanthine to form xanthine IEA Drosophila melanogaster 57692 R-DME-74258 https://reactome.org/PathwayBrowser/#/R-DME-74258 XDH oxidizes xanthine to form urate IEA Drosophila melanogaster 57692 R-DME-75879 https://reactome.org/PathwayBrowser/#/R-DME-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Drosophila melanogaster 57692 R-DME-77299 https://reactome.org/PathwayBrowser/#/R-DME-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 57692 R-DME-77319 https://reactome.org/PathwayBrowser/#/R-DME-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Drosophila melanogaster 57692 R-DME-77327 https://reactome.org/PathwayBrowser/#/R-DME-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 57692 R-DME-77338 https://reactome.org/PathwayBrowser/#/R-DME-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 57692 R-DME-77345 https://reactome.org/PathwayBrowser/#/R-DME-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 57692 R-DME-880007 https://reactome.org/PathwayBrowser/#/R-DME-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Drosophila melanogaster 57692 R-DME-880050 https://reactome.org/PathwayBrowser/#/R-DME-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Drosophila melanogaster 57692 R-DME-8955817 https://reactome.org/PathwayBrowser/#/R-DME-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Drosophila melanogaster 57692 R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 57692 R-DME-9727349 https://reactome.org/PathwayBrowser/#/R-DME-9727349 XDH dehydrogenates xanthine to form urate IEA Drosophila melanogaster 57692 R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 57692 R-DME-9853499 https://reactome.org/PathwayBrowser/#/R-DME-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 57692 R-DME-9853512 https://reactome.org/PathwayBrowser/#/R-DME-9853512 DLST transfers succinyl to CoA IEA Drosophila melanogaster 57692 R-DME-9854672 https://reactome.org/PathwayBrowser/#/R-DME-9854672 FAD attaches to SDHA IEA Drosophila melanogaster 57692 R-DME-9861616 https://reactome.org/PathwayBrowser/#/R-DME-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 57692 R-DME-9861667 https://reactome.org/PathwayBrowser/#/R-DME-9861667 DLAT trimer transfers acetyl to CoA IEA Drosophila melanogaster 57692 R-DME-9861734 https://reactome.org/PathwayBrowser/#/R-DME-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Drosophila melanogaster 57692 R-DRE-1222376 https://reactome.org/PathwayBrowser/#/R-DRE-1222376 NOX2 generates superoxide from oxygen IEA Danio rerio 57692 R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 57692 R-DRE-141200 https://reactome.org/PathwayBrowser/#/R-DRE-141200 MAOB:FAD oxidatively deaminates of PEA IEA Danio rerio 57692 R-DRE-141202 https://reactome.org/PathwayBrowser/#/R-DRE-141202 MAOB:FAD oxidatively deaminates TYR IEA Danio rerio 57692 R-DRE-141348 https://reactome.org/PathwayBrowser/#/R-DRE-141348 PAO:FAD oxidises NASPM to PTCN IEA Danio rerio 57692 R-DRE-141351 https://reactome.org/PathwayBrowser/#/R-DRE-141351 PAOX:FAD oxidises NASPN to SPM IEA Danio rerio 57692 R-DRE-163217 https://reactome.org/PathwayBrowser/#/R-DRE-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Danio rerio 57692 R-DRE-1655453 https://reactome.org/PathwayBrowser/#/R-DRE-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Danio rerio 57692 R-DRE-169260 https://reactome.org/PathwayBrowser/#/R-DRE-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Danio rerio 57692 R-DRE-169270 https://reactome.org/PathwayBrowser/#/R-DRE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Danio rerio 57692 R-DRE-189423 https://reactome.org/PathwayBrowser/#/R-DRE-189423 PPO oxidises PPGEN9 to PRIN9 IEA Danio rerio 57692 R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 57692 R-DRE-196929 https://reactome.org/PathwayBrowser/#/R-DRE-196929 FLAD1 phosphorylates FMN IEA Danio rerio 57692 R-DRE-196955 https://reactome.org/PathwayBrowser/#/R-DRE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Danio rerio 57692 R-DRE-198824 https://reactome.org/PathwayBrowser/#/R-DRE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Danio rerio 57692 R-DRE-203565 https://reactome.org/PathwayBrowser/#/R-DRE-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Danio rerio 57692 R-DRE-203625 https://reactome.org/PathwayBrowser/#/R-DRE-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Danio rerio 57692 R-DRE-2066787 https://reactome.org/PathwayBrowser/#/R-DRE-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Danio rerio 57692 R-DRE-2162186 https://reactome.org/PathwayBrowser/#/R-DRE-2162186 COQ3 methylates DeMQ10H2 IEA Danio rerio 57692 R-DRE-2162188 https://reactome.org/PathwayBrowser/#/R-DRE-2162188 COQ5 methylates MDMQ10H2 IEA Danio rerio 57692 R-DRE-2162193 https://reactome.org/PathwayBrowser/#/R-DRE-2162193 COQ3 methylates DHDB IEA Danio rerio 57692 R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 57692 R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 57692 R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 57692 R-DRE-2395512 https://reactome.org/PathwayBrowser/#/R-DRE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Danio rerio 57692 R-DRE-2395517 https://reactome.org/PathwayBrowser/#/R-DRE-2395517 NADPH transfers electrons to FDXR IEA Danio rerio 57692 R-DRE-3165230 https://reactome.org/PathwayBrowser/#/R-DRE-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Danio rerio 57692 R-DRE-3204311 https://reactome.org/PathwayBrowser/#/R-DRE-3204311 AOX1 oxidises PXL to PDXate IEA Danio rerio 57692 R-DRE-389821 https://reactome.org/PathwayBrowser/#/R-DRE-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Danio rerio 57692 R-DRE-389891 https://reactome.org/PathwayBrowser/#/R-DRE-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Danio rerio 57692 R-DRE-390256 https://reactome.org/PathwayBrowser/#/R-DRE-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Danio rerio 57692 R-DRE-5218827 https://reactome.org/PathwayBrowser/#/R-DRE-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Danio rerio 57692 R-DRE-5218841 https://reactome.org/PathwayBrowser/#/R-DRE-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Danio rerio 57692 R-DRE-5694018 https://reactome.org/PathwayBrowser/#/R-DRE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Danio rerio 57692 R-DRE-5695989 https://reactome.org/PathwayBrowser/#/R-DRE-5695989 ACAD11 dehydrogenates BH-CoA IEA Danio rerio 57692 R-DRE-6797913 https://reactome.org/PathwayBrowser/#/R-DRE-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Danio rerio 57692 R-DRE-6799197 https://reactome.org/PathwayBrowser/#/R-DRE-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Danio rerio 57692 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 57692 R-DRE-70745 https://reactome.org/PathwayBrowser/#/R-DRE-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Danio rerio 57692 R-DRE-70859 https://reactome.org/PathwayBrowser/#/R-DRE-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Danio rerio 57692 R-DRE-71037 https://reactome.org/PathwayBrowser/#/R-DRE-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Danio rerio 57692 R-DRE-71046 https://reactome.org/PathwayBrowser/#/R-DRE-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Danio rerio 57692 R-DRE-71401 https://reactome.org/PathwayBrowser/#/R-DRE-71401 OGDH dimer decarboxylates 2-OG IEA Danio rerio 57692 R-DRE-73585 https://reactome.org/PathwayBrowser/#/R-DRE-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Danio rerio 57692 R-DRE-73616 https://reactome.org/PathwayBrowser/#/R-DRE-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Danio rerio 57692 R-DRE-77263 https://reactome.org/PathwayBrowser/#/R-DRE-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Danio rerio 57692 R-DRE-77274 https://reactome.org/PathwayBrowser/#/R-DRE-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Danio rerio 57692 R-DRE-77299 https://reactome.org/PathwayBrowser/#/R-DRE-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Danio rerio 57692 R-DRE-77319 https://reactome.org/PathwayBrowser/#/R-DRE-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Danio rerio 57692 R-DRE-77327 https://reactome.org/PathwayBrowser/#/R-DRE-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Danio rerio 57692 R-DRE-880007 https://reactome.org/PathwayBrowser/#/R-DRE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Danio rerio 57692 R-DRE-8865107 https://reactome.org/PathwayBrowser/#/R-DRE-8865107 MICAL1 produces NADP+, H2O2 IEA Danio rerio 57692 R-DRE-8956458 https://reactome.org/PathwayBrowser/#/R-DRE-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Danio rerio 57692 R-DRE-9677929 https://reactome.org/PathwayBrowser/#/R-DRE-9677929 MAOB inhibitors bind MAOB:FAD IEA Danio rerio 57692 R-DRE-9853499 https://reactome.org/PathwayBrowser/#/R-DRE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Danio rerio 57692 R-DRE-9853512 https://reactome.org/PathwayBrowser/#/R-DRE-9853512 DLST transfers succinyl to CoA IEA Danio rerio 57692 R-DRE-9854672 https://reactome.org/PathwayBrowser/#/R-DRE-9854672 FAD attaches to SDHA IEA Danio rerio 57692 R-GGA-109341 https://reactome.org/PathwayBrowser/#/R-GGA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Gallus gallus 57692 R-GGA-1222376 https://reactome.org/PathwayBrowser/#/R-GGA-1222376 NOX2 generates superoxide from oxygen IEA Gallus gallus 57692 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 57692 R-GGA-141186 https://reactome.org/PathwayBrowser/#/R-GGA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Gallus gallus 57692 R-GGA-141200 https://reactome.org/PathwayBrowser/#/R-GGA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Gallus gallus 57692 R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus 57692 R-GGA-141348 https://reactome.org/PathwayBrowser/#/R-GGA-141348 PAO:FAD oxidises NASPM to PTCN IEA Gallus gallus 57692 R-GGA-141351 https://reactome.org/PathwayBrowser/#/R-GGA-141351 PAOX:FAD oxidises NASPN to SPM IEA Gallus gallus 57692 R-GGA-1497784 https://reactome.org/PathwayBrowser/#/R-GGA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Gallus gallus 57692 R-GGA-1497796 https://reactome.org/PathwayBrowser/#/R-GGA-1497796 BH2 binding can lead to eNOS uncoupling IEA Gallus gallus 57692 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 57692 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Gallus gallus 57692 R-GGA-174374 https://reactome.org/PathwayBrowser/#/R-GGA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Gallus gallus 57692 R-GGA-188467 https://reactome.org/PathwayBrowser/#/R-GGA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Gallus gallus 57692 R-GGA-189423 https://reactome.org/PathwayBrowser/#/R-GGA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Gallus gallus 57692 R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 57692 R-GGA-192335 https://reactome.org/PathwayBrowser/#/R-GGA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Gallus gallus 57692 R-GGA-193369 https://reactome.org/PathwayBrowser/#/R-GGA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Gallus gallus 57692 R-GGA-196929 https://reactome.org/PathwayBrowser/#/R-GGA-196929 FLAD1 phosphorylates FMN IEA Gallus gallus 57692 R-GGA-198824 https://reactome.org/PathwayBrowser/#/R-GGA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Gallus gallus 57692 R-GGA-202110 https://reactome.org/PathwayBrowser/#/R-GGA-202110 eNOS:Caveolin-1 complex binds to CaM IEA Gallus gallus 57692 R-GGA-202111 https://reactome.org/PathwayBrowser/#/R-GGA-202111 AKT1 phosphorylates eNOS IEA Gallus gallus 57692 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 57692 R-GGA-202129 https://reactome.org/PathwayBrowser/#/R-GGA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Gallus gallus 57692 R-GGA-202132 https://reactome.org/PathwayBrowser/#/R-GGA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Gallus gallus 57692 R-GGA-202137 https://reactome.org/PathwayBrowser/#/R-GGA-202137 AKT1 binds eNOS complex via HSP90 IEA Gallus gallus 57692 R-GGA-202144 https://reactome.org/PathwayBrowser/#/R-GGA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Gallus gallus 57692 R-GGA-203565 https://reactome.org/PathwayBrowser/#/R-GGA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Gallus gallus 57692 R-GGA-203613 https://reactome.org/PathwayBrowser/#/R-GGA-203613 depalmitoylation of eNOS IEA Gallus gallus 57692 R-GGA-203625 https://reactome.org/PathwayBrowser/#/R-GGA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Gallus gallus 57692 R-GGA-203700 https://reactome.org/PathwayBrowser/#/R-GGA-203700 eNOS translocation from Golgi to Caveolae IEA Gallus gallus 57692 R-GGA-203712 https://reactome.org/PathwayBrowser/#/R-GGA-203712 eNOS associates with Caveolin-1 IEA Gallus gallus 57692 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 57692 R-GGA-204169 https://reactome.org/PathwayBrowser/#/R-GGA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Gallus gallus 57692 R-GGA-2066787 https://reactome.org/PathwayBrowser/#/R-GGA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Gallus gallus 57692 R-GGA-2162186 https://reactome.org/PathwayBrowser/#/R-GGA-2162186 COQ3 methylates DeMQ10H2 IEA Gallus gallus 57692 R-GGA-2162188 https://reactome.org/PathwayBrowser/#/R-GGA-2162188 COQ5 methylates MDMQ10H2 IEA Gallus gallus 57692 R-GGA-2162193 https://reactome.org/PathwayBrowser/#/R-GGA-2162193 COQ3 methylates DHDB IEA Gallus gallus 57692 R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 57692 R-GGA-2395512 https://reactome.org/PathwayBrowser/#/R-GGA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Gallus gallus 57692 R-GGA-2395517 https://reactome.org/PathwayBrowser/#/R-GGA-2395517 NADPH transfers electrons to FDXR IEA Gallus gallus 57692 R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus 57692 R-GGA-3149539 https://reactome.org/PathwayBrowser/#/R-GGA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Gallus gallus 57692 R-GGA-3159253 https://reactome.org/PathwayBrowser/#/R-GGA-3159253 MMAB adenosylates cob(I)alamin IEA Gallus gallus 57692 R-GGA-3165230 https://reactome.org/PathwayBrowser/#/R-GGA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Gallus gallus 57692 R-GGA-3204311 https://reactome.org/PathwayBrowser/#/R-GGA-3204311 AOX1 oxidises PXL to PDXate IEA Gallus gallus 57692 R-GGA-3204318 https://reactome.org/PathwayBrowser/#/R-GGA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Gallus gallus 57692 R-GGA-3323050 https://reactome.org/PathwayBrowser/#/R-GGA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Gallus gallus 57692 R-GGA-3323079 https://reactome.org/PathwayBrowser/#/R-GGA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 57692 R-GGA-373129 https://reactome.org/PathwayBrowser/#/R-GGA-373129 fumarate + FADH2 <=> succinate + FAD IEA Gallus gallus 57692 R-GGA-373147 https://reactome.org/PathwayBrowser/#/R-GGA-373147 succinate + FAD <=> fumarate + FADH2 IEA Gallus gallus 57692 R-GGA-374909 https://reactome.org/PathwayBrowser/#/R-GGA-374909 Catabolism of Noradrenaline IEA Gallus gallus 57692 R-GGA-379382 https://reactome.org/PathwayBrowser/#/R-GGA-379382 MAOA:FAD deaminates DA to DOPAC IEA Gallus gallus 57692 R-GGA-379395 https://reactome.org/PathwayBrowser/#/R-GGA-379395 MAOA:FAD deaminates 3MT to HVA IEA Gallus gallus 57692 R-GGA-389821 https://reactome.org/PathwayBrowser/#/R-GGA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Gallus gallus 57692 R-GGA-389889 https://reactome.org/PathwayBrowser/#/R-GGA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Gallus gallus 57692 R-GGA-389891 https://reactome.org/PathwayBrowser/#/R-GGA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Gallus gallus 57692 R-GGA-390256 https://reactome.org/PathwayBrowser/#/R-GGA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Gallus gallus 57692 R-GGA-421452 https://reactome.org/PathwayBrowser/#/R-GGA-421452 2 protoporphyrinogen IX + 3 O2 => 2 protoporphyrin IX + 6 H2O IEA Gallus gallus 57692 R-GGA-5218827 https://reactome.org/PathwayBrowser/#/R-GGA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Gallus gallus 57692 R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus 57692 R-GGA-5263614 https://reactome.org/PathwayBrowser/#/R-GGA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Gallus gallus 57692 R-GGA-5263616 https://reactome.org/PathwayBrowser/#/R-GGA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Gallus gallus 57692 R-GGA-5693153 https://reactome.org/PathwayBrowser/#/R-GGA-5693153 PPM1K dephosphorylates p-BCKDH IEA Gallus gallus 57692 R-GGA-5694018 https://reactome.org/PathwayBrowser/#/R-GGA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Gallus gallus 57692 R-GGA-5695989 https://reactome.org/PathwayBrowser/#/R-GGA-5695989 ACAD11 dehydrogenates BH-CoA IEA Gallus gallus 57692 R-GGA-6797653 https://reactome.org/PathwayBrowser/#/R-GGA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Gallus gallus 57692 R-GGA-6797913 https://reactome.org/PathwayBrowser/#/R-GGA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Gallus gallus 57692 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus 57692 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus 57692 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus 57692 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus 57692 R-GGA-6799197 https://reactome.org/PathwayBrowser/#/R-GGA-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Gallus gallus 57692 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus 57692 R-GGA-6799203 https://reactome.org/PathwayBrowser/#/R-GGA-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Gallus gallus 57692 R-GGA-6800868 https://reactome.org/PathwayBrowser/#/R-GGA-6800868 NDUF subunits bind to form the IP subcomplex IEA Gallus gallus 57692 R-GGA-6810076 https://reactome.org/PathwayBrowser/#/R-GGA-6810076 DDO oxidizes D-Asp to OA IEA Gallus gallus 57692 R-GGA-70670 https://reactome.org/PathwayBrowser/#/R-GGA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Gallus gallus 57692 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 57692 R-GGA-70745 https://reactome.org/PathwayBrowser/#/R-GGA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Gallus gallus 57692 R-GGA-70800 https://reactome.org/PathwayBrowser/#/R-GGA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Gallus gallus 57692 R-GGA-70859 https://reactome.org/PathwayBrowser/#/R-GGA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Gallus gallus 57692 R-GGA-71037 https://reactome.org/PathwayBrowser/#/R-GGA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Gallus gallus 57692 R-GGA-71046 https://reactome.org/PathwayBrowser/#/R-GGA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Gallus gallus 57692 R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus 57692 R-GGA-71682 https://reactome.org/PathwayBrowser/#/R-GGA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 57692 R-GGA-73585 https://reactome.org/PathwayBrowser/#/R-GGA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Gallus gallus 57692 R-GGA-73616 https://reactome.org/PathwayBrowser/#/R-GGA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Gallus gallus 57692 R-GGA-73646 https://reactome.org/PathwayBrowser/#/R-GGA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Gallus gallus 57692 R-GGA-74247 https://reactome.org/PathwayBrowser/#/R-GGA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Gallus gallus 57692 R-GGA-74258 https://reactome.org/PathwayBrowser/#/R-GGA-74258 XDH oxidizes xanthine to form urate IEA Gallus gallus 57692 R-GGA-77263 https://reactome.org/PathwayBrowser/#/R-GGA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Gallus gallus 57692 R-GGA-77274 https://reactome.org/PathwayBrowser/#/R-GGA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Gallus gallus 57692 R-GGA-77319 https://reactome.org/PathwayBrowser/#/R-GGA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Gallus gallus 57692 R-GGA-77327 https://reactome.org/PathwayBrowser/#/R-GGA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Gallus gallus 57692 R-GGA-77338 https://reactome.org/PathwayBrowser/#/R-GGA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Gallus gallus 57692 R-GGA-77345 https://reactome.org/PathwayBrowser/#/R-GGA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Gallus gallus 57692 R-GGA-880007 https://reactome.org/PathwayBrowser/#/R-GGA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus 57692 R-GGA-880050 https://reactome.org/PathwayBrowser/#/R-GGA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus 57692 R-GGA-8865107 https://reactome.org/PathwayBrowser/#/R-GGA-8865107 MICAL1 produces NADP+, H2O2 IEA Gallus gallus 57692 R-GGA-8936519 https://reactome.org/PathwayBrowser/#/R-GGA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Gallus gallus 57692 R-GGA-8956458 https://reactome.org/PathwayBrowser/#/R-GGA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Gallus gallus 57692 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus 57692 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus 57692 R-GGA-917811 https://reactome.org/PathwayBrowser/#/R-GGA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Gallus gallus 57692 R-GGA-9677917 https://reactome.org/PathwayBrowser/#/R-GGA-9677917 MAOA inhibitors bind MAOA:FAD IEA Gallus gallus 57692 R-GGA-9677929 https://reactome.org/PathwayBrowser/#/R-GGA-9677929 MAOB inhibitors bind MAOB:FAD IEA Gallus gallus 57692 R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 57692 R-GGA-9727349 https://reactome.org/PathwayBrowser/#/R-GGA-9727349 XDH dehydrogenates xanthine to form urate IEA Gallus gallus 57692 R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 57692 R-GGA-9853499 https://reactome.org/PathwayBrowser/#/R-GGA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 57692 R-GGA-9853512 https://reactome.org/PathwayBrowser/#/R-GGA-9853512 DLST transfers succinyl to CoA IEA Gallus gallus 57692 R-GGA-9854672 https://reactome.org/PathwayBrowser/#/R-GGA-9854672 FAD attaches to SDHA IEA Gallus gallus 57692 R-GGA-9861616 https://reactome.org/PathwayBrowser/#/R-GGA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 57692 R-GGA-9861667 https://reactome.org/PathwayBrowser/#/R-GGA-9861667 DLAT trimer transfers acetyl to CoA IEA Gallus gallus 57692 R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus 57692 R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 57692 R-HSA-109341 https://reactome.org/PathwayBrowser/#/R-HSA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA TAS Homo sapiens 57692 R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 57692 R-HSA-1222376 https://reactome.org/PathwayBrowser/#/R-HSA-1222376 NOX2 generates superoxide from oxygen TAS Homo sapiens 57692 R-HSA-1222412 https://reactome.org/PathwayBrowser/#/R-HSA-1222412 lpdC dimer reactivates dlaT TAS Homo sapiens 57692 R-HSA-1222485 https://reactome.org/PathwayBrowser/#/R-HSA-1222485 TrxB reactivates TrxA TAS Homo sapiens 57692 R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 57692 R-HSA-141186 https://reactome.org/PathwayBrowser/#/R-HSA-141186 MAOA:FAD oxidatively deaminates of 5HT TAS Homo sapiens 57692 R-HSA-141200 https://reactome.org/PathwayBrowser/#/R-HSA-141200 MAOB:FAD oxidatively deaminates of PEA TAS Homo sapiens 57692 R-HSA-141202 https://reactome.org/PathwayBrowser/#/R-HSA-141202 MAOB:FAD oxidatively deaminates TYR TAS Homo sapiens 57692 R-HSA-141348 https://reactome.org/PathwayBrowser/#/R-HSA-141348 PAO:FAD oxidises NASPM to PTCN TAS Homo sapiens 57692 R-HSA-141351 https://reactome.org/PathwayBrowser/#/R-HSA-141351 PAOX:FAD oxidises NASPN to SPM TAS Homo sapiens 57692 R-HSA-1497784 https://reactome.org/PathwayBrowser/#/R-HSA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle TAS Homo sapiens 57692 R-HSA-1497796 https://reactome.org/PathwayBrowser/#/R-HSA-1497796 BH2 binding can lead to eNOS uncoupling TAS Homo sapiens 57692 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 57692 R-HSA-1614665 https://reactome.org/PathwayBrowser/#/R-HSA-1614665 SQR oxidizes sulfide to bound persulfide IEA Homo sapiens 57692 R-HSA-163217 https://reactome.org/PathwayBrowser/#/R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 TAS Homo sapiens 57692 R-HSA-1655453 https://reactome.org/PathwayBrowser/#/R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU TAS Homo sapiens 57692 R-HSA-169260 https://reactome.org/PathwayBrowser/#/R-HSA-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF TAS Homo sapiens 57692 R-HSA-169270 https://reactome.org/PathwayBrowser/#/R-HSA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 TAS Homo sapiens 57692 R-HSA-174374 https://reactome.org/PathwayBrowser/#/R-HSA-174374 MTR transfers CH3 from MeCbl to HCYS TAS Homo sapiens 57692 R-HSA-188467 https://reactome.org/PathwayBrowser/#/R-HSA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) TAS Homo sapiens 57692 R-HSA-189423 https://reactome.org/PathwayBrowser/#/R-HSA-189423 PPO oxidises PPGEN9 to PRIN9 TAS Homo sapiens 57692 R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 57692 R-HSA-192335 https://reactome.org/PathwayBrowser/#/R-HSA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) TAS Homo sapiens 57692 R-HSA-193369 https://reactome.org/PathwayBrowser/#/R-HSA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA TAS Homo sapiens 57692 R-HSA-196929 https://reactome.org/PathwayBrowser/#/R-HSA-196929 FLAD1 phosphorylates FMN TAS Homo sapiens 57692 R-HSA-196955 https://reactome.org/PathwayBrowser/#/R-HSA-196955 2xENPP1 hydrolyzes FAD to FMN TAS Homo sapiens 57692 R-HSA-198824 https://reactome.org/PathwayBrowser/#/R-HSA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme TAS Homo sapiens 57692 R-HSA-202110 https://reactome.org/PathwayBrowser/#/R-HSA-202110 eNOS:Caveolin-1 complex binds to CaM TAS Homo sapiens 57692 R-HSA-202111 https://reactome.org/PathwayBrowser/#/R-HSA-202111 AKT1 phosphorylates eNOS TAS Homo sapiens 57692 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 57692 R-HSA-202129 https://reactome.org/PathwayBrowser/#/R-HSA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex TAS Homo sapiens 57692 R-HSA-202132 https://reactome.org/PathwayBrowser/#/R-HSA-202132 depalmitoylated eNOS translocates from plasma membrane TAS Homo sapiens 57692 R-HSA-202137 https://reactome.org/PathwayBrowser/#/R-HSA-202137 AKT1 binds eNOS complex via HSP90 TAS Homo sapiens 57692 R-HSA-202144 https://reactome.org/PathwayBrowser/#/R-HSA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex TAS Homo sapiens 57692 R-HSA-203553 https://reactome.org/PathwayBrowser/#/R-HSA-203553 eNOS binds NOSIP TAS Homo sapiens 57692 R-HSA-203565 https://reactome.org/PathwayBrowser/#/R-HSA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP TAS Homo sapiens 57692 R-HSA-203613 https://reactome.org/PathwayBrowser/#/R-HSA-203613 depalmitoylation of eNOS TAS Homo sapiens 57692 R-HSA-203625 https://reactome.org/PathwayBrowser/#/R-HSA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane TAS Homo sapiens 57692 R-HSA-203662 https://reactome.org/PathwayBrowser/#/R-HSA-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 TAS Homo sapiens 57692 R-HSA-203680 https://reactome.org/PathwayBrowser/#/R-HSA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments TAS Homo sapiens 57692 R-HSA-203700 https://reactome.org/PathwayBrowser/#/R-HSA-203700 eNOS translocation from Golgi to Caveolae TAS Homo sapiens 57692 R-HSA-203712 https://reactome.org/PathwayBrowser/#/R-HSA-203712 eNOS associates with Caveolin-1 TAS Homo sapiens 57692 R-HSA-203716 https://reactome.org/PathwayBrowser/#/R-HSA-203716 eNOS:Caveolin-1 complex binds to Nostrin TAS Homo sapiens 57692 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 57692 R-HSA-204169 https://reactome.org/PathwayBrowser/#/R-HSA-204169 PDP1,2 dephosphorylate p-lipo-PDH TAS Homo sapiens 57692 R-HSA-2066787 https://reactome.org/PathwayBrowser/#/R-HSA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA TAS Homo sapiens 57692 R-HSA-2160492 https://reactome.org/PathwayBrowser/#/R-HSA-2160492 IL4I1:FAD oxidises L-Phe to kPPV TAS Homo sapiens 57692 R-HSA-2162186 https://reactome.org/PathwayBrowser/#/R-HSA-2162186 COQ3 methylates DeMQ10H2 TAS Homo sapiens 57692 R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB IEA Homo sapiens 57692 R-HSA-2162188 https://reactome.org/PathwayBrowser/#/R-HSA-2162188 COQ5 methylates MDMQ10H2 TAS Homo sapiens 57692 R-HSA-2162193 https://reactome.org/PathwayBrowser/#/R-HSA-2162193 COQ3 methylates DHDB TAS Homo sapiens 57692 R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 57692 R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 57692 R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 57692 R-HSA-2395512 https://reactome.org/PathwayBrowser/#/R-HSA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) TAS Homo sapiens 57692 R-HSA-2395517 https://reactome.org/PathwayBrowser/#/R-HSA-2395517 NADPH transfers electrons to FDXR TAS Homo sapiens 57692 R-HSA-2408542 https://reactome.org/PathwayBrowser/#/R-HSA-2408542 GSSeSG is reduced to GSSeH and GSH by GSR IEA Homo sapiens 57692 R-HSA-2408558 https://reactome.org/PathwayBrowser/#/R-HSA-2408558 SeO3(2-) is reduced to H2Se by TXNRD1 IEA Homo sapiens 57692 R-HSA-2564824 https://reactome.org/PathwayBrowser/#/R-HSA-2564824 NADPH reduces NDOR1:CIAPIN1 IEA Homo sapiens 57692 R-HSA-2564826 https://reactome.org/PathwayBrowser/#/R-HSA-2564826 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold IEA Homo sapiens 57692 R-HSA-3149518 https://reactome.org/PathwayBrowser/#/R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl TAS Homo sapiens 57692 R-HSA-3149539 https://reactome.org/PathwayBrowser/#/R-HSA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin TAS Homo sapiens 57692 R-HSA-3159253 https://reactome.org/PathwayBrowser/#/R-HSA-3159253 MMAB adenosylates cob(I)alamin TAS Homo sapiens 57692 R-HSA-3165230 https://reactome.org/PathwayBrowser/#/R-HSA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol TAS Homo sapiens 57692 R-HSA-3204311 https://reactome.org/PathwayBrowser/#/R-HSA-3204311 AOX1 oxidises PXL to PDXate TAS Homo sapiens 57692 R-HSA-3204318 https://reactome.org/PathwayBrowser/#/R-HSA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR TAS Homo sapiens 57692 R-HSA-3318563 https://reactome.org/PathwayBrowser/#/R-HSA-3318563 Defective MTRR does not convert cob(II)alamin to MeCbl TAS Homo sapiens 57692 R-HSA-3321918 https://reactome.org/PathwayBrowser/#/R-HSA-3321918 Defective MTR does not transfer CH3 group from MTHF to cob(I)alamin TAS Homo sapiens 57692 R-HSA-3322140 https://reactome.org/PathwayBrowser/#/R-HSA-3322140 Defective MTR does not transfer CH3 group from MeCbl to HCYS TAS Homo sapiens 57692 R-HSA-3323050 https://reactome.org/PathwayBrowser/#/R-HSA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH TAS Homo sapiens 57692 R-HSA-3323079 https://reactome.org/PathwayBrowser/#/R-HSA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 57692 R-HSA-374909 https://reactome.org/PathwayBrowser/#/R-HSA-374909 Catabolism of Noradrenaline TAS Homo sapiens 57692 R-HSA-379382 https://reactome.org/PathwayBrowser/#/R-HSA-379382 MAOA:FAD deaminates DA to DOPAC TAS Homo sapiens 57692 R-HSA-379395 https://reactome.org/PathwayBrowser/#/R-HSA-379395 MAOA:FAD deaminates 3MT to HVA TAS Homo sapiens 57692 R-HSA-389821 https://reactome.org/PathwayBrowser/#/R-HSA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ TAS Homo sapiens 57692 R-HSA-389889 https://reactome.org/PathwayBrowser/#/R-HSA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA TAS Homo sapiens 57692 R-HSA-389891 https://reactome.org/PathwayBrowser/#/R-HSA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) TAS Homo sapiens 57692 R-HSA-390256 https://reactome.org/PathwayBrowser/#/R-HSA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 TAS Homo sapiens 57692 R-HSA-390427 https://reactome.org/PathwayBrowser/#/R-HSA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate TAS Homo sapiens 57692 R-HSA-5218827 https://reactome.org/PathwayBrowser/#/R-HSA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 TAS Homo sapiens 57692 R-HSA-5218841 https://reactome.org/PathwayBrowser/#/R-HSA-5218841 NADPH oxidase 2 generates superoxide from oxygen TAS Homo sapiens 57692 R-HSA-5263614 https://reactome.org/PathwayBrowser/#/R-HSA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 TAS Homo sapiens 57692 R-HSA-5263616 https://reactome.org/PathwayBrowser/#/R-HSA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 TAS Homo sapiens 57692 R-HSA-5602966 https://reactome.org/PathwayBrowser/#/R-HSA-5602966 Defective FMO3 does not N-oxidise TMA TAS Homo sapiens 57692 R-HSA-5603108 https://reactome.org/PathwayBrowser/#/R-HSA-5603108 Defective MAOA does not oxidatively deaminate 5HT TAS Homo sapiens 57692 R-HSA-5693148 https://reactome.org/PathwayBrowser/#/R-HSA-5693148 BCKDK phosphorylates BCKDH TAS Homo sapiens 57692 R-HSA-5693153 https://reactome.org/PathwayBrowser/#/R-HSA-5693153 PPM1K dephosphorylates p-BCKDH TAS Homo sapiens 57692 R-HSA-5694018 https://reactome.org/PathwayBrowser/#/R-HSA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate TAS Homo sapiens 57692 R-HSA-5695980 https://reactome.org/PathwayBrowser/#/R-HSA-5695980 ACAD10 dehydrogenates S-2MPDA-CoA TAS Homo sapiens 57692 R-HSA-5695989 https://reactome.org/PathwayBrowser/#/R-HSA-5695989 ACAD11 dehydrogenates BH-CoA TAS Homo sapiens 57692 R-HSA-6784224 https://reactome.org/PathwayBrowser/#/R-HSA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate TAS Homo sapiens 57692 R-HSA-6797653 https://reactome.org/PathwayBrowser/#/R-HSA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC TAS Homo sapiens 57692 R-HSA-6797913 https://reactome.org/PathwayBrowser/#/R-HSA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly TAS Homo sapiens 57692 R-HSA-6799178 https://reactome.org/PathwayBrowser/#/R-HSA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 TAS Homo sapiens 57692 R-HSA-6799179 https://reactome.org/PathwayBrowser/#/R-HSA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex TAS Homo sapiens 57692 R-HSA-6799191 https://reactome.org/PathwayBrowser/#/R-HSA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex TAS Homo sapiens 57692 R-HSA-6799196 https://reactome.org/PathwayBrowser/#/R-HSA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I TAS Homo sapiens 57692 R-HSA-6799197 https://reactome.org/PathwayBrowser/#/R-HSA-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex TAS Homo sapiens 57692 R-HSA-6799202 https://reactome.org/PathwayBrowser/#/R-HSA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex TAS Homo sapiens 57692 R-HSA-6799203 https://reactome.org/PathwayBrowser/#/R-HSA-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 TAS Homo sapiens 57692 R-HSA-6800868 https://reactome.org/PathwayBrowser/#/R-HSA-6800868 NDUF subunits bind to form the IP subcomplex TAS Homo sapiens 57692 R-HSA-6810076 https://reactome.org/PathwayBrowser/#/R-HSA-6810076 DDO oxidizes D-Asp to OA TAS Homo sapiens 57692 R-HSA-70670 https://reactome.org/PathwayBrowser/#/R-HSA-70670 PRODH oxidises L-Pro to 1PYR-5COOH TAS Homo sapiens 57692 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 57692 R-HSA-70745 https://reactome.org/PathwayBrowser/#/R-HSA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 TAS Homo sapiens 57692 R-HSA-70800 https://reactome.org/PathwayBrowser/#/R-HSA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 TAS Homo sapiens 57692 R-HSA-70859 https://reactome.org/PathwayBrowser/#/R-HSA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 TAS Homo sapiens 57692 R-HSA-71037 https://reactome.org/PathwayBrowser/#/R-HSA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ TAS Homo sapiens 57692 R-HSA-71046 https://reactome.org/PathwayBrowser/#/R-HSA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 TAS Homo sapiens 57692 R-HSA-71401 https://reactome.org/PathwayBrowser/#/R-HSA-71401 OGDH dimer decarboxylates 2-OG TAS Homo sapiens 57692 R-HSA-71682 https://reactome.org/PathwayBrowser/#/R-HSA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 57692 R-HSA-73585 https://reactome.org/PathwayBrowser/#/R-HSA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ TAS Homo sapiens 57692 R-HSA-73616 https://reactome.org/PathwayBrowser/#/R-HSA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ TAS Homo sapiens 57692 R-HSA-73646 https://reactome.org/PathwayBrowser/#/R-HSA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ TAS Homo sapiens 57692 R-HSA-74247 https://reactome.org/PathwayBrowser/#/R-HSA-74247 XDH oxidizes hypoxanthine to form xanthine TAS Homo sapiens 57692 R-HSA-74258 https://reactome.org/PathwayBrowser/#/R-HSA-74258 XDH oxidizes xanthine to form urate TAS Homo sapiens 57692 R-HSA-75879 https://reactome.org/PathwayBrowser/#/R-HSA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH TAS Homo sapiens 57692 R-HSA-77263 https://reactome.org/PathwayBrowser/#/R-HSA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 TAS Homo sapiens 57692 R-HSA-77274 https://reactome.org/PathwayBrowser/#/R-HSA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 TAS Homo sapiens 57692 R-HSA-77299 https://reactome.org/PathwayBrowser/#/R-HSA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 TAS Homo sapiens 57692 R-HSA-77319 https://reactome.org/PathwayBrowser/#/R-HSA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 TAS Homo sapiens 57692 R-HSA-77327 https://reactome.org/PathwayBrowser/#/R-HSA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 TAS Homo sapiens 57692 R-HSA-77338 https://reactome.org/PathwayBrowser/#/R-HSA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 TAS Homo sapiens 57692 R-HSA-77345 https://reactome.org/PathwayBrowser/#/R-HSA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 TAS Homo sapiens 57692 R-HSA-880007 https://reactome.org/PathwayBrowser/#/R-HSA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 TAS Homo sapiens 57692 R-HSA-880050 https://reactome.org/PathwayBrowser/#/R-HSA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 TAS Homo sapiens 57692 R-HSA-8865107 https://reactome.org/PathwayBrowser/#/R-HSA-8865107 MICAL1 produces NADP+, H2O2 TAS Homo sapiens 57692 R-HSA-8936519 https://reactome.org/PathwayBrowser/#/R-HSA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones TAS Homo sapiens 57692 R-HSA-8955817 https://reactome.org/PathwayBrowser/#/R-HSA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH TAS Homo sapiens 57692 R-HSA-8956458 https://reactome.org/PathwayBrowser/#/R-HSA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ TAS Homo sapiens 57692 R-HSA-9013145 https://reactome.org/PathwayBrowser/#/R-HSA-9013145 RAC1 binds effectors at the plasma membrane TAS Homo sapiens 57692 R-HSA-9018808 https://reactome.org/PathwayBrowser/#/R-HSA-9018808 RAC3 binds effectors at the plasma membrane TAS Homo sapiens 57692 R-HSA-917811 https://reactome.org/PathwayBrowser/#/R-HSA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ TAS Homo sapiens 57692 R-HSA-9677917 https://reactome.org/PathwayBrowser/#/R-HSA-9677917 MAOA inhibitors bind MAOA:FAD TAS Homo sapiens 57692 R-HSA-9677929 https://reactome.org/PathwayBrowser/#/R-HSA-9677929 MAOB inhibitors bind MAOB:FAD TAS Homo sapiens 57692 R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 57692 R-HSA-9727349 https://reactome.org/PathwayBrowser/#/R-HSA-9727349 XDH dehydrogenates xanthine to form urate TAS Homo sapiens 57692 R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 57692 R-HSA-9759186 https://reactome.org/PathwayBrowser/#/R-HSA-9759186 AcK-NFE2L2- dependent NQO1 gene expression TAS Homo sapiens 57692 R-HSA-9761843 https://reactome.org/PathwayBrowser/#/R-HSA-9761843 NFE2L2-dependent GSR gene expression TAS Homo sapiens 57692 R-HSA-9853499 https://reactome.org/PathwayBrowser/#/R-HSA-9853499 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 57692 R-HSA-9853512 https://reactome.org/PathwayBrowser/#/R-HSA-9853512 DLST transfers succinyl to CoA TAS Homo sapiens 57692 R-HSA-9854672 https://reactome.org/PathwayBrowser/#/R-HSA-9854672 FAD attaches to SDHA TAS Homo sapiens 57692 R-HSA-9861616 https://reactome.org/PathwayBrowser/#/R-HSA-9861616 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 57692 R-HSA-9861667 https://reactome.org/PathwayBrowser/#/R-HSA-9861667 DLAT trimer transfers acetyl to CoA TAS Homo sapiens 57692 R-HSA-9861734 https://reactome.org/PathwayBrowser/#/R-HSA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT TAS Homo sapiens 57692 R-MMU-109341 https://reactome.org/PathwayBrowser/#/R-MMU-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Mus musculus 57692 R-MMU-1222376 https://reactome.org/PathwayBrowser/#/R-MMU-1222376 NOX2 generates superoxide from oxygen IEA Mus musculus 57692 R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 57692 R-MMU-141186 https://reactome.org/PathwayBrowser/#/R-MMU-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Mus musculus 57692 R-MMU-141200 https://reactome.org/PathwayBrowser/#/R-MMU-141200 MAOB:FAD oxidatively deaminates of PEA IEA Mus musculus 57692 R-MMU-141202 https://reactome.org/PathwayBrowser/#/R-MMU-141202 MAOB:FAD oxidatively deaminates TYR IEA Mus musculus 57692 R-MMU-141348 https://reactome.org/PathwayBrowser/#/R-MMU-141348 PAO:FAD oxidises NASPM to PTCN IEA Mus musculus 57692 R-MMU-141351 https://reactome.org/PathwayBrowser/#/R-MMU-141351 PAOX:FAD oxidises NASPN to SPM IEA Mus musculus 57692 R-MMU-1497784 https://reactome.org/PathwayBrowser/#/R-MMU-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Mus musculus 57692 R-MMU-1497796 https://reactome.org/PathwayBrowser/#/R-MMU-1497796 BH2 binding can lead to eNOS uncoupling IEA Mus musculus 57692 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 57692 R-MMU-163217 https://reactome.org/PathwayBrowser/#/R-MMU-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Mus musculus 57692 R-MMU-1655453 https://reactome.org/PathwayBrowser/#/R-MMU-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Mus musculus 57692 R-MMU-169260 https://reactome.org/PathwayBrowser/#/R-MMU-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Mus musculus 57692 R-MMU-169270 https://reactome.org/PathwayBrowser/#/R-MMU-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Mus musculus 57692 R-MMU-174374 https://reactome.org/PathwayBrowser/#/R-MMU-174374 MTR transfers CH3 from MeCbl to HCYS IEA Mus musculus 57692 R-MMU-188467 https://reactome.org/PathwayBrowser/#/R-MMU-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Mus musculus 57692 R-MMU-189423 https://reactome.org/PathwayBrowser/#/R-MMU-189423 PPO oxidises PPGEN9 to PRIN9 IEA Mus musculus 57692 R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 57692 R-MMU-192335 https://reactome.org/PathwayBrowser/#/R-MMU-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Mus musculus 57692 R-MMU-193369 https://reactome.org/PathwayBrowser/#/R-MMU-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Mus musculus 57692 R-MMU-196929 https://reactome.org/PathwayBrowser/#/R-MMU-196929 FLAD1 phosphorylates FMN IEA Mus musculus 57692 R-MMU-196955 https://reactome.org/PathwayBrowser/#/R-MMU-196955 2xENPP1 hydrolyzes FAD to FMN IEA Mus musculus 57692 R-MMU-198824 https://reactome.org/PathwayBrowser/#/R-MMU-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Mus musculus 57692 R-MMU-202110 https://reactome.org/PathwayBrowser/#/R-MMU-202110 eNOS:Caveolin-1 complex binds to CaM IEA Mus musculus 57692 R-MMU-202111 https://reactome.org/PathwayBrowser/#/R-MMU-202111 AKT1 phosphorylates eNOS IEA Mus musculus 57692 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 57692 R-MMU-202129 https://reactome.org/PathwayBrowser/#/R-MMU-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Mus musculus 57692 R-MMU-202132 https://reactome.org/PathwayBrowser/#/R-MMU-202132 depalmitoylated eNOS translocates from plasma membrane IEA Mus musculus 57692 R-MMU-202137 https://reactome.org/PathwayBrowser/#/R-MMU-202137 AKT1 binds eNOS complex via HSP90 IEA Mus musculus 57692 R-MMU-202144 https://reactome.org/PathwayBrowser/#/R-MMU-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Mus musculus 57692 R-MMU-203553 https://reactome.org/PathwayBrowser/#/R-MMU-203553 eNOS binds NOSIP IEA Mus musculus 57692 R-MMU-203613 https://reactome.org/PathwayBrowser/#/R-MMU-203613 depalmitoylation of eNOS IEA Mus musculus 57692 R-MMU-203625 https://reactome.org/PathwayBrowser/#/R-MMU-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Mus musculus 57692 R-MMU-203662 https://reactome.org/PathwayBrowser/#/R-MMU-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Mus musculus 57692 R-MMU-203680 https://reactome.org/PathwayBrowser/#/R-MMU-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Mus musculus 57692 R-MMU-203700 https://reactome.org/PathwayBrowser/#/R-MMU-203700 eNOS translocation from Golgi to Caveolae IEA Mus musculus 57692 R-MMU-203712 https://reactome.org/PathwayBrowser/#/R-MMU-203712 eNOS associates with Caveolin-1 IEA Mus musculus 57692 R-MMU-203716 https://reactome.org/PathwayBrowser/#/R-MMU-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Mus musculus 57692 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 57692 R-MMU-204169 https://reactome.org/PathwayBrowser/#/R-MMU-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Mus musculus 57692 R-MMU-2066787 https://reactome.org/PathwayBrowser/#/R-MMU-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Mus musculus 57692 R-MMU-2160492 https://reactome.org/PathwayBrowser/#/R-MMU-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Mus musculus 57692 R-MMU-2162186 https://reactome.org/PathwayBrowser/#/R-MMU-2162186 COQ3 methylates DeMQ10H2 IEA Mus musculus 57692 R-MMU-2162188 https://reactome.org/PathwayBrowser/#/R-MMU-2162188 COQ5 methylates MDMQ10H2 IEA Mus musculus 57692 R-MMU-2162193 https://reactome.org/PathwayBrowser/#/R-MMU-2162193 COQ3 methylates DHDB IEA Mus musculus 57692 R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 57692 R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 57692 R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 57692 R-MMU-2395512 https://reactome.org/PathwayBrowser/#/R-MMU-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Mus musculus 57692 R-MMU-2395517 https://reactome.org/PathwayBrowser/#/R-MMU-2395517 NADPH transfers electrons to FDXR IEA Mus musculus 57692 R-MMU-3149518 https://reactome.org/PathwayBrowser/#/R-MMU-3149518 MTRR reduces cob(II)alamin to meCbl IEA Mus musculus 57692 R-MMU-3149539 https://reactome.org/PathwayBrowser/#/R-MMU-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Mus musculus 57692 R-MMU-3159253 https://reactome.org/PathwayBrowser/#/R-MMU-3159253 MMAB adenosylates cob(I)alamin IEA Mus musculus 57692 R-MMU-3165230 https://reactome.org/PathwayBrowser/#/R-MMU-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Mus musculus 57692 R-MMU-3204311 https://reactome.org/PathwayBrowser/#/R-MMU-3204311 AOX1 oxidises PXL to PDXate IEA Mus musculus 57692 R-MMU-3204318 https://reactome.org/PathwayBrowser/#/R-MMU-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Mus musculus 57692 R-MMU-3323050 https://reactome.org/PathwayBrowser/#/R-MMU-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Mus musculus 57692 R-MMU-3323079 https://reactome.org/PathwayBrowser/#/R-MMU-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 57692 R-MMU-374909 https://reactome.org/PathwayBrowser/#/R-MMU-374909 Catabolism of Noradrenaline IEA Mus musculus 57692 R-MMU-379382 https://reactome.org/PathwayBrowser/#/R-MMU-379382 MAOA:FAD deaminates DA to DOPAC IEA Mus musculus 57692 R-MMU-379395 https://reactome.org/PathwayBrowser/#/R-MMU-379395 MAOA:FAD deaminates 3MT to HVA IEA Mus musculus 57692 R-MMU-389821 https://reactome.org/PathwayBrowser/#/R-MMU-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Mus musculus 57692 R-MMU-389889 https://reactome.org/PathwayBrowser/#/R-MMU-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Mus musculus 57692 R-MMU-389891 https://reactome.org/PathwayBrowser/#/R-MMU-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Mus musculus 57692 R-MMU-390256 https://reactome.org/PathwayBrowser/#/R-MMU-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Mus musculus 57692 R-MMU-390427 https://reactome.org/PathwayBrowser/#/R-MMU-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Mus musculus 57692 R-MMU-5218827 https://reactome.org/PathwayBrowser/#/R-MMU-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Mus musculus 57692 R-MMU-5218841 https://reactome.org/PathwayBrowser/#/R-MMU-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Mus musculus 57692 R-MMU-5263614 https://reactome.org/PathwayBrowser/#/R-MMU-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Mus musculus 57692 R-MMU-5263616 https://reactome.org/PathwayBrowser/#/R-MMU-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Mus musculus 57692 R-MMU-5693148 https://reactome.org/PathwayBrowser/#/R-MMU-5693148 BCKDK phosphorylates BCKDH IEA Mus musculus 57692 R-MMU-5693153 https://reactome.org/PathwayBrowser/#/R-MMU-5693153 PPM1K dephosphorylates p-BCKDH IEA Mus musculus 57692 R-MMU-5694018 https://reactome.org/PathwayBrowser/#/R-MMU-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Mus musculus 57692 R-MMU-5695980 https://reactome.org/PathwayBrowser/#/R-MMU-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Mus musculus 57692 R-MMU-5695989 https://reactome.org/PathwayBrowser/#/R-MMU-5695989 ACAD11 dehydrogenates BH-CoA IEA Mus musculus 57692 R-MMU-6784224 https://reactome.org/PathwayBrowser/#/R-MMU-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Mus musculus 57692 R-MMU-6797653 https://reactome.org/PathwayBrowser/#/R-MMU-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Mus musculus 57692 R-MMU-6797913 https://reactome.org/PathwayBrowser/#/R-MMU-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Mus musculus 57692 R-MMU-6799178 https://reactome.org/PathwayBrowser/#/R-MMU-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Mus musculus 57692 R-MMU-6799179 https://reactome.org/PathwayBrowser/#/R-MMU-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Mus musculus 57692 R-MMU-6799191 https://reactome.org/PathwayBrowser/#/R-MMU-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Mus musculus 57692 R-MMU-6799196 https://reactome.org/PathwayBrowser/#/R-MMU-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Mus musculus 57692 R-MMU-6799197 https://reactome.org/PathwayBrowser/#/R-MMU-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Mus musculus 57692 R-MMU-6799202 https://reactome.org/PathwayBrowser/#/R-MMU-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Mus musculus 57692 R-MMU-6799203 https://reactome.org/PathwayBrowser/#/R-MMU-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Mus musculus 57692 R-MMU-6800868 https://reactome.org/PathwayBrowser/#/R-MMU-6800868 NDUF subunits bind to form the IP subcomplex IEA Mus musculus 57692 R-MMU-6810076 https://reactome.org/PathwayBrowser/#/R-MMU-6810076 DDO oxidizes D-Asp to OA IEA Mus musculus 57692 R-MMU-70670 https://reactome.org/PathwayBrowser/#/R-MMU-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Mus musculus 57692 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 57692 R-MMU-70745 https://reactome.org/PathwayBrowser/#/R-MMU-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Mus musculus 57692 R-MMU-70800 https://reactome.org/PathwayBrowser/#/R-MMU-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Mus musculus 57692 R-MMU-70859 https://reactome.org/PathwayBrowser/#/R-MMU-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Mus musculus 57692 R-MMU-71037 https://reactome.org/PathwayBrowser/#/R-MMU-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Mus musculus 57692 R-MMU-71046 https://reactome.org/PathwayBrowser/#/R-MMU-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Mus musculus 57692 R-MMU-71401 https://reactome.org/PathwayBrowser/#/R-MMU-71401 OGDH dimer decarboxylates 2-OG IEA Mus musculus 57692 R-MMU-71682 https://reactome.org/PathwayBrowser/#/R-MMU-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 57692 R-MMU-73585 https://reactome.org/PathwayBrowser/#/R-MMU-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Mus musculus 57692 R-MMU-73616 https://reactome.org/PathwayBrowser/#/R-MMU-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Mus musculus 57692 R-MMU-73646 https://reactome.org/PathwayBrowser/#/R-MMU-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Mus musculus 57692 R-MMU-74247 https://reactome.org/PathwayBrowser/#/R-MMU-74247 XDH oxidizes hypoxanthine to form xanthine IEA Mus musculus 57692 R-MMU-74258 https://reactome.org/PathwayBrowser/#/R-MMU-74258 XDH oxidizes xanthine to form urate IEA Mus musculus 57692 R-MMU-75879 https://reactome.org/PathwayBrowser/#/R-MMU-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Mus musculus 57692 R-MMU-77263 https://reactome.org/PathwayBrowser/#/R-MMU-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Mus musculus 57692 R-MMU-77274 https://reactome.org/PathwayBrowser/#/R-MMU-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Mus musculus 57692 R-MMU-77299 https://reactome.org/PathwayBrowser/#/R-MMU-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Mus musculus 57692 R-MMU-77319 https://reactome.org/PathwayBrowser/#/R-MMU-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Mus musculus 57692 R-MMU-77327 https://reactome.org/PathwayBrowser/#/R-MMU-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Mus musculus 57692 R-MMU-77338 https://reactome.org/PathwayBrowser/#/R-MMU-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Mus musculus 57692 R-MMU-77345 https://reactome.org/PathwayBrowser/#/R-MMU-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Mus musculus 57692 R-MMU-880007 https://reactome.org/PathwayBrowser/#/R-MMU-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Mus musculus 57692 R-MMU-880050 https://reactome.org/PathwayBrowser/#/R-MMU-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Mus musculus 57692 R-MMU-8936519 https://reactome.org/PathwayBrowser/#/R-MMU-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Mus musculus 57692 R-MMU-8955817 https://reactome.org/PathwayBrowser/#/R-MMU-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Mus musculus 57692 R-MMU-8956458 https://reactome.org/PathwayBrowser/#/R-MMU-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Mus musculus 57692 R-MMU-9013145 https://reactome.org/PathwayBrowser/#/R-MMU-9013145 RAC1 binds effectors at the plasma membrane IEA Mus musculus 57692 R-MMU-9018808 https://reactome.org/PathwayBrowser/#/R-MMU-9018808 RAC3 binds effectors at the plasma membrane IEA Mus musculus 57692 R-MMU-917811 https://reactome.org/PathwayBrowser/#/R-MMU-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Mus musculus 57692 R-MMU-9677917 https://reactome.org/PathwayBrowser/#/R-MMU-9677917 MAOA inhibitors bind MAOA:FAD IEA Mus musculus 57692 R-MMU-9677929 https://reactome.org/PathwayBrowser/#/R-MMU-9677929 MAOB inhibitors bind MAOB:FAD IEA Mus musculus 57692 R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 57692 R-MMU-9727349 https://reactome.org/PathwayBrowser/#/R-MMU-9727349 XDH dehydrogenates xanthine to form urate IEA Mus musculus 57692 R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 57692 R-MMU-9853499 https://reactome.org/PathwayBrowser/#/R-MMU-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 57692 R-MMU-9853512 https://reactome.org/PathwayBrowser/#/R-MMU-9853512 DLST transfers succinyl to CoA IEA Mus musculus 57692 R-MMU-9854672 https://reactome.org/PathwayBrowser/#/R-MMU-9854672 FAD attaches to SDHA IEA Mus musculus 57692 R-MMU-9861616 https://reactome.org/PathwayBrowser/#/R-MMU-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 57692 R-MMU-9861667 https://reactome.org/PathwayBrowser/#/R-MMU-9861667 DLAT trimer transfers acetyl to CoA IEA Mus musculus 57692 R-MMU-9861734 https://reactome.org/PathwayBrowser/#/R-MMU-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Mus musculus 57692 R-PFA-1497784 https://reactome.org/PathwayBrowser/#/R-PFA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Plasmodium falciparum 57692 R-PFA-1497796 https://reactome.org/PathwayBrowser/#/R-PFA-1497796 BH2 binding can lead to eNOS uncoupling IEA Plasmodium falciparum 57692 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 57692 R-PFA-188467 https://reactome.org/PathwayBrowser/#/R-PFA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Plasmodium falciparum 57692 R-PFA-189423 https://reactome.org/PathwayBrowser/#/R-PFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Plasmodium falciparum 57692 R-PFA-196929 https://reactome.org/PathwayBrowser/#/R-PFA-196929 FLAD1 phosphorylates FMN IEA Plasmodium falciparum 57692 R-PFA-202111 https://reactome.org/PathwayBrowser/#/R-PFA-202111 AKT1 phosphorylates eNOS IEA Plasmodium falciparum 57692 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 57692 R-PFA-202132 https://reactome.org/PathwayBrowser/#/R-PFA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Plasmodium falciparum 57692 R-PFA-203553 https://reactome.org/PathwayBrowser/#/R-PFA-203553 eNOS binds NOSIP IEA Plasmodium falciparum 57692 R-PFA-203680 https://reactome.org/PathwayBrowser/#/R-PFA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Plasmodium falciparum 57692 R-PFA-203700 https://reactome.org/PathwayBrowser/#/R-PFA-203700 eNOS translocation from Golgi to Caveolae IEA Plasmodium falciparum 57692 R-PFA-2160492 https://reactome.org/PathwayBrowser/#/R-PFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Plasmodium falciparum 57692 R-PFA-2395512 https://reactome.org/PathwayBrowser/#/R-PFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Plasmodium falciparum 57692 R-PFA-2395517 https://reactome.org/PathwayBrowser/#/R-PFA-2395517 NADPH transfers electrons to FDXR IEA Plasmodium falciparum 57692 R-PFA-3323079 https://reactome.org/PathwayBrowser/#/R-PFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 57692 R-PFA-5263614 https://reactome.org/PathwayBrowser/#/R-PFA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Plasmodium falciparum 57692 R-PFA-5263616 https://reactome.org/PathwayBrowser/#/R-PFA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Plasmodium falciparum 57692 R-PFA-5694018 https://reactome.org/PathwayBrowser/#/R-PFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Plasmodium falciparum 57692 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 57692 R-PFA-71401 https://reactome.org/PathwayBrowser/#/R-PFA-71401 OGDH dimer decarboxylates 2-OG IEA Plasmodium falciparum 57692 R-PFA-71682 https://reactome.org/PathwayBrowser/#/R-PFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 57692 R-PFA-73646 https://reactome.org/PathwayBrowser/#/R-PFA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Plasmodium falciparum 57692 R-PFA-9853499 https://reactome.org/PathwayBrowser/#/R-PFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Plasmodium falciparum 57692 R-PFA-9853512 https://reactome.org/PathwayBrowser/#/R-PFA-9853512 DLST transfers succinyl to CoA IEA Plasmodium falciparum 57692 R-RNO-109341 https://reactome.org/PathwayBrowser/#/R-RNO-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Rattus norvegicus 57692 R-RNO-1222376 https://reactome.org/PathwayBrowser/#/R-RNO-1222376 NOX2 generates superoxide from oxygen IEA Rattus norvegicus 57692 R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 57692 R-RNO-141186 https://reactome.org/PathwayBrowser/#/R-RNO-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Rattus norvegicus 57692 R-RNO-141200 https://reactome.org/PathwayBrowser/#/R-RNO-141200 MAOB:FAD oxidatively deaminates of PEA IEA Rattus norvegicus 57692 R-RNO-141202 https://reactome.org/PathwayBrowser/#/R-RNO-141202 MAOB:FAD oxidatively deaminates TYR IEA Rattus norvegicus 57692 R-RNO-141348 https://reactome.org/PathwayBrowser/#/R-RNO-141348 PAO:FAD oxidises NASPM to PTCN IEA Rattus norvegicus 57692 R-RNO-141351 https://reactome.org/PathwayBrowser/#/R-RNO-141351 PAOX:FAD oxidises NASPN to SPM IEA Rattus norvegicus 57692 R-RNO-1497784 https://reactome.org/PathwayBrowser/#/R-RNO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Rattus norvegicus 57692 R-RNO-1497796 https://reactome.org/PathwayBrowser/#/R-RNO-1497796 BH2 binding can lead to eNOS uncoupling IEA Rattus norvegicus 57692 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 57692 R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Rattus norvegicus 57692 R-RNO-1655453 https://reactome.org/PathwayBrowser/#/R-RNO-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Rattus norvegicus 57692 R-RNO-169260 https://reactome.org/PathwayBrowser/#/R-RNO-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Rattus norvegicus 57692 R-RNO-169270 https://reactome.org/PathwayBrowser/#/R-RNO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Rattus norvegicus 57692 R-RNO-174374 https://reactome.org/PathwayBrowser/#/R-RNO-174374 MTR transfers CH3 from MeCbl to HCYS IEA Rattus norvegicus 57692 R-RNO-188467 https://reactome.org/PathwayBrowser/#/R-RNO-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Rattus norvegicus 57692 R-RNO-189423 https://reactome.org/PathwayBrowser/#/R-RNO-189423 PPO oxidises PPGEN9 to PRIN9 IEA Rattus norvegicus 57692 R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 57692 R-RNO-192335 https://reactome.org/PathwayBrowser/#/R-RNO-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Rattus norvegicus 57692 R-RNO-193369 https://reactome.org/PathwayBrowser/#/R-RNO-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Rattus norvegicus 57692 R-RNO-196929 https://reactome.org/PathwayBrowser/#/R-RNO-196929 FLAD1 phosphorylates FMN IEA Rattus norvegicus 57692 R-RNO-196955 https://reactome.org/PathwayBrowser/#/R-RNO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Rattus norvegicus 57692 R-RNO-198824 https://reactome.org/PathwayBrowser/#/R-RNO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Rattus norvegicus 57692 R-RNO-202110 https://reactome.org/PathwayBrowser/#/R-RNO-202110 eNOS:Caveolin-1 complex binds to CaM IEA Rattus norvegicus 57692 R-RNO-202111 https://reactome.org/PathwayBrowser/#/R-RNO-202111 AKT1 phosphorylates eNOS IEA Rattus norvegicus 57692 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 57692 R-RNO-202129 https://reactome.org/PathwayBrowser/#/R-RNO-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Rattus norvegicus 57692 R-RNO-202132 https://reactome.org/PathwayBrowser/#/R-RNO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Rattus norvegicus 57692 R-RNO-202137 https://reactome.org/PathwayBrowser/#/R-RNO-202137 AKT1 binds eNOS complex via HSP90 IEA Rattus norvegicus 57692 R-RNO-202144 https://reactome.org/PathwayBrowser/#/R-RNO-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Rattus norvegicus 57692 R-RNO-203553 https://reactome.org/PathwayBrowser/#/R-RNO-203553 eNOS binds NOSIP IEA Rattus norvegicus 57692 R-RNO-203613 https://reactome.org/PathwayBrowser/#/R-RNO-203613 depalmitoylation of eNOS IEA Rattus norvegicus 57692 R-RNO-203625 https://reactome.org/PathwayBrowser/#/R-RNO-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Rattus norvegicus 57692 R-RNO-203662 https://reactome.org/PathwayBrowser/#/R-RNO-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Rattus norvegicus 57692 R-RNO-203680 https://reactome.org/PathwayBrowser/#/R-RNO-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Rattus norvegicus 57692 R-RNO-203700 https://reactome.org/PathwayBrowser/#/R-RNO-203700 eNOS translocation from Golgi to Caveolae IEA Rattus norvegicus 57692 R-RNO-203712 https://reactome.org/PathwayBrowser/#/R-RNO-203712 eNOS associates with Caveolin-1 IEA Rattus norvegicus 57692 R-RNO-203716 https://reactome.org/PathwayBrowser/#/R-RNO-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Rattus norvegicus 57692 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 57692 R-RNO-204169 https://reactome.org/PathwayBrowser/#/R-RNO-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Rattus norvegicus 57692 R-RNO-2066787 https://reactome.org/PathwayBrowser/#/R-RNO-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Rattus norvegicus 57692 R-RNO-2160492 https://reactome.org/PathwayBrowser/#/R-RNO-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Rattus norvegicus 57692 R-RNO-2162186 https://reactome.org/PathwayBrowser/#/R-RNO-2162186 COQ3 methylates DeMQ10H2 IEA Rattus norvegicus 57692 R-RNO-2162188 https://reactome.org/PathwayBrowser/#/R-RNO-2162188 COQ5 methylates MDMQ10H2 IEA Rattus norvegicus 57692 R-RNO-2162193 https://reactome.org/PathwayBrowser/#/R-RNO-2162193 COQ3 methylates DHDB IEA Rattus norvegicus 57692 R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 57692 R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 57692 R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 57692 R-RNO-2395512 https://reactome.org/PathwayBrowser/#/R-RNO-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Rattus norvegicus 57692 R-RNO-2395517 https://reactome.org/PathwayBrowser/#/R-RNO-2395517 NADPH transfers electrons to FDXR IEA Rattus norvegicus 57692 R-RNO-2408514 https://reactome.org/PathwayBrowser/#/R-RNO-2408514 GSSeSG is reduced to GSSeH and GSH by Gsr TAS Rattus norvegicus 57692 R-RNO-3149518 https://reactome.org/PathwayBrowser/#/R-RNO-3149518 MTRR reduces cob(II)alamin to meCbl IEA Rattus norvegicus 57692 R-RNO-3149539 https://reactome.org/PathwayBrowser/#/R-RNO-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Rattus norvegicus 57692 R-RNO-3159253 https://reactome.org/PathwayBrowser/#/R-RNO-3159253 MMAB adenosylates cob(I)alamin IEA Rattus norvegicus 57692 R-RNO-3165230 https://reactome.org/PathwayBrowser/#/R-RNO-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Rattus norvegicus 57692 R-RNO-3204311 https://reactome.org/PathwayBrowser/#/R-RNO-3204311 AOX1 oxidises PXL to PDXate IEA Rattus norvegicus 57692 R-RNO-3204318 https://reactome.org/PathwayBrowser/#/R-RNO-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Rattus norvegicus 57692 R-RNO-3323050 https://reactome.org/PathwayBrowser/#/R-RNO-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Rattus norvegicus 57692 R-RNO-3323079 https://reactome.org/PathwayBrowser/#/R-RNO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 57692 R-RNO-374909 https://reactome.org/PathwayBrowser/#/R-RNO-374909 Catabolism of Noradrenaline IEA Rattus norvegicus 57692 R-RNO-379382 https://reactome.org/PathwayBrowser/#/R-RNO-379382 MAOA:FAD deaminates DA to DOPAC IEA Rattus norvegicus 57692 R-RNO-379395 https://reactome.org/PathwayBrowser/#/R-RNO-379395 MAOA:FAD deaminates 3MT to HVA IEA Rattus norvegicus 57692 R-RNO-389821 https://reactome.org/PathwayBrowser/#/R-RNO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Rattus norvegicus 57692 R-RNO-389889 https://reactome.org/PathwayBrowser/#/R-RNO-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Rattus norvegicus 57692 R-RNO-389891 https://reactome.org/PathwayBrowser/#/R-RNO-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Rattus norvegicus 57692 R-RNO-390256 https://reactome.org/PathwayBrowser/#/R-RNO-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Rattus norvegicus 57692 R-RNO-390427 https://reactome.org/PathwayBrowser/#/R-RNO-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Rattus norvegicus 57692 R-RNO-5218827 https://reactome.org/PathwayBrowser/#/R-RNO-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Rattus norvegicus 57692 R-RNO-5218841 https://reactome.org/PathwayBrowser/#/R-RNO-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Rattus norvegicus 57692 R-RNO-5263614 https://reactome.org/PathwayBrowser/#/R-RNO-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Rattus norvegicus 57692 R-RNO-5263616 https://reactome.org/PathwayBrowser/#/R-RNO-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Rattus norvegicus 57692 R-RNO-5693148 https://reactome.org/PathwayBrowser/#/R-RNO-5693148 BCKDK phosphorylates BCKDH IEA Rattus norvegicus 57692 R-RNO-5693153 https://reactome.org/PathwayBrowser/#/R-RNO-5693153 PPM1K dephosphorylates p-BCKDH IEA Rattus norvegicus 57692 R-RNO-5694018 https://reactome.org/PathwayBrowser/#/R-RNO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Rattus norvegicus 57692 R-RNO-5695989 https://reactome.org/PathwayBrowser/#/R-RNO-5695989 ACAD11 dehydrogenates BH-CoA IEA Rattus norvegicus 57692 R-RNO-6784224 https://reactome.org/PathwayBrowser/#/R-RNO-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Rattus norvegicus 57692 R-RNO-6797653 https://reactome.org/PathwayBrowser/#/R-RNO-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Rattus norvegicus 57692 R-RNO-6797913 https://reactome.org/PathwayBrowser/#/R-RNO-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Rattus norvegicus 57692 R-RNO-6799178 https://reactome.org/PathwayBrowser/#/R-RNO-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Rattus norvegicus 57692 R-RNO-6799179 https://reactome.org/PathwayBrowser/#/R-RNO-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Rattus norvegicus 57692 R-RNO-6799191 https://reactome.org/PathwayBrowser/#/R-RNO-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Rattus norvegicus 57692 R-RNO-6799196 https://reactome.org/PathwayBrowser/#/R-RNO-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Rattus norvegicus 57692 R-RNO-6799197 https://reactome.org/PathwayBrowser/#/R-RNO-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Rattus norvegicus 57692 R-RNO-6799202 https://reactome.org/PathwayBrowser/#/R-RNO-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Rattus norvegicus 57692 R-RNO-6799203 https://reactome.org/PathwayBrowser/#/R-RNO-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Rattus norvegicus 57692 R-RNO-6800868 https://reactome.org/PathwayBrowser/#/R-RNO-6800868 NDUF subunits bind to form the IP subcomplex IEA Rattus norvegicus 57692 R-RNO-6810076 https://reactome.org/PathwayBrowser/#/R-RNO-6810076 DDO oxidizes D-Asp to OA IEA Rattus norvegicus 57692 R-RNO-70670 https://reactome.org/PathwayBrowser/#/R-RNO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Rattus norvegicus 57692 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 57692 R-RNO-70745 https://reactome.org/PathwayBrowser/#/R-RNO-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Rattus norvegicus 57692 R-RNO-70800 https://reactome.org/PathwayBrowser/#/R-RNO-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Rattus norvegicus 57692 R-RNO-70859 https://reactome.org/PathwayBrowser/#/R-RNO-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Rattus norvegicus 57692 R-RNO-71037 https://reactome.org/PathwayBrowser/#/R-RNO-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 57692 R-RNO-71046 https://reactome.org/PathwayBrowser/#/R-RNO-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Rattus norvegicus 57692 R-RNO-71401 https://reactome.org/PathwayBrowser/#/R-RNO-71401 OGDH dimer decarboxylates 2-OG IEA Rattus norvegicus 57692 R-RNO-71682 https://reactome.org/PathwayBrowser/#/R-RNO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 57692 R-RNO-73585 https://reactome.org/PathwayBrowser/#/R-RNO-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Rattus norvegicus 57692 R-RNO-73616 https://reactome.org/PathwayBrowser/#/R-RNO-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Rattus norvegicus 57692 R-RNO-73646 https://reactome.org/PathwayBrowser/#/R-RNO-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Rattus norvegicus 57692 R-RNO-74247 https://reactome.org/PathwayBrowser/#/R-RNO-74247 XDH oxidizes hypoxanthine to form xanthine IEA Rattus norvegicus 57692 R-RNO-74258 https://reactome.org/PathwayBrowser/#/R-RNO-74258 XDH oxidizes xanthine to form urate IEA Rattus norvegicus 57692 R-RNO-75879 https://reactome.org/PathwayBrowser/#/R-RNO-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Rattus norvegicus 57692 R-RNO-77263 https://reactome.org/PathwayBrowser/#/R-RNO-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Rattus norvegicus 57692 R-RNO-77274 https://reactome.org/PathwayBrowser/#/R-RNO-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 57692 R-RNO-77299 https://reactome.org/PathwayBrowser/#/R-RNO-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 57692 R-RNO-77319 https://reactome.org/PathwayBrowser/#/R-RNO-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Rattus norvegicus 57692 R-RNO-77327 https://reactome.org/PathwayBrowser/#/R-RNO-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 57692 R-RNO-77338 https://reactome.org/PathwayBrowser/#/R-RNO-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 57692 R-RNO-77345 https://reactome.org/PathwayBrowser/#/R-RNO-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 57692 R-RNO-880007 https://reactome.org/PathwayBrowser/#/R-RNO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Rattus norvegicus 57692 R-RNO-880050 https://reactome.org/PathwayBrowser/#/R-RNO-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Rattus norvegicus 57692 R-RNO-8936519 https://reactome.org/PathwayBrowser/#/R-RNO-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Rattus norvegicus 57692 R-RNO-8955817 https://reactome.org/PathwayBrowser/#/R-RNO-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Rattus norvegicus 57692 R-RNO-8956458 https://reactome.org/PathwayBrowser/#/R-RNO-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Rattus norvegicus 57692 R-RNO-9013145 https://reactome.org/PathwayBrowser/#/R-RNO-9013145 RAC1 binds effectors at the plasma membrane IEA Rattus norvegicus 57692 R-RNO-917811 https://reactome.org/PathwayBrowser/#/R-RNO-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Rattus norvegicus 57692 R-RNO-9677917 https://reactome.org/PathwayBrowser/#/R-RNO-9677917 MAOA inhibitors bind MAOA:FAD IEA Rattus norvegicus 57692 R-RNO-9677929 https://reactome.org/PathwayBrowser/#/R-RNO-9677929 MAOB inhibitors bind MAOB:FAD IEA Rattus norvegicus 57692 R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 57692 R-RNO-9727349 https://reactome.org/PathwayBrowser/#/R-RNO-9727349 XDH dehydrogenates xanthine to form urate IEA Rattus norvegicus 57692 R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 57692 R-RNO-9853499 https://reactome.org/PathwayBrowser/#/R-RNO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 57692 R-RNO-9853512 https://reactome.org/PathwayBrowser/#/R-RNO-9853512 DLST transfers succinyl to CoA IEA Rattus norvegicus 57692 R-RNO-9854672 https://reactome.org/PathwayBrowser/#/R-RNO-9854672 FAD attaches to SDHA IEA Rattus norvegicus 57692 R-RNO-9861616 https://reactome.org/PathwayBrowser/#/R-RNO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 57692 R-RNO-9861667 https://reactome.org/PathwayBrowser/#/R-RNO-9861667 DLAT trimer transfers acetyl to CoA IEA Rattus norvegicus 57692 R-RNO-9861734 https://reactome.org/PathwayBrowser/#/R-RNO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Rattus norvegicus 57692 R-SCE-1497784 https://reactome.org/PathwayBrowser/#/R-SCE-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Saccharomyces cerevisiae 57692 R-SCE-1497796 https://reactome.org/PathwayBrowser/#/R-SCE-1497796 BH2 binding can lead to eNOS uncoupling IEA Saccharomyces cerevisiae 57692 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 57692 R-SCE-169260 https://reactome.org/PathwayBrowser/#/R-SCE-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Saccharomyces cerevisiae 57692 R-SCE-169270 https://reactome.org/PathwayBrowser/#/R-SCE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Saccharomyces cerevisiae 57692 R-SCE-188467 https://reactome.org/PathwayBrowser/#/R-SCE-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Saccharomyces cerevisiae 57692 R-SCE-189423 https://reactome.org/PathwayBrowser/#/R-SCE-189423 PPO oxidises PPGEN9 to PRIN9 IEA Saccharomyces cerevisiae 57692 R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 57692 R-SCE-196929 https://reactome.org/PathwayBrowser/#/R-SCE-196929 FLAD1 phosphorylates FMN IEA Saccharomyces cerevisiae 57692 R-SCE-196955 https://reactome.org/PathwayBrowser/#/R-SCE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Saccharomyces cerevisiae 57692 R-SCE-198824 https://reactome.org/PathwayBrowser/#/R-SCE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Saccharomyces cerevisiae 57692 R-SCE-202111 https://reactome.org/PathwayBrowser/#/R-SCE-202111 AKT1 phosphorylates eNOS IEA Saccharomyces cerevisiae 57692 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 57692 R-SCE-202132 https://reactome.org/PathwayBrowser/#/R-SCE-202132 depalmitoylated eNOS translocates from plasma membrane IEA Saccharomyces cerevisiae 57692 R-SCE-203613 https://reactome.org/PathwayBrowser/#/R-SCE-203613 depalmitoylation of eNOS IEA Saccharomyces cerevisiae 57692 R-SCE-203700 https://reactome.org/PathwayBrowser/#/R-SCE-203700 eNOS translocation from Golgi to Caveolae IEA Saccharomyces cerevisiae 57692 R-SCE-2162186 https://reactome.org/PathwayBrowser/#/R-SCE-2162186 COQ3 methylates DeMQ10H2 IEA Saccharomyces cerevisiae 57692 R-SCE-2162188 https://reactome.org/PathwayBrowser/#/R-SCE-2162188 COQ5 methylates MDMQ10H2 IEA Saccharomyces cerevisiae 57692 R-SCE-2162193 https://reactome.org/PathwayBrowser/#/R-SCE-2162193 COQ3 methylates DHDB IEA Saccharomyces cerevisiae 57692 R-SCE-2162194 https://reactome.org/PathwayBrowser/#/R-SCE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Saccharomyces cerevisiae 57692 R-SCE-2162292 https://reactome.org/PathwayBrowser/#/R-SCE-2162292 HHB is hydroxylated to DHHB by Coq6 TAS Saccharomyces cerevisiae 57692 R-SCE-2395512 https://reactome.org/PathwayBrowser/#/R-SCE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Saccharomyces cerevisiae 57692 R-SCE-2395517 https://reactome.org/PathwayBrowser/#/R-SCE-2395517 NADPH transfers electrons to FDXR IEA Saccharomyces cerevisiae 57692 R-SCE-2564819 https://reactome.org/PathwayBrowser/#/R-SCE-2564819 NADPH reduces TAH18:DRE2 TAS Saccharomyces cerevisiae 57692 R-SCE-2564822 https://reactome.org/PathwayBrowser/#/R-SCE-2564822 4Fe-4S cluster assembles on CFD1:NBP35 scaffold TAS Saccharomyces cerevisiae 57692 R-SCE-3323079 https://reactome.org/PathwayBrowser/#/R-SCE-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 57692 R-SCE-389891 https://reactome.org/PathwayBrowser/#/R-SCE-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Saccharomyces cerevisiae 57692 R-SCE-5694018 https://reactome.org/PathwayBrowser/#/R-SCE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Saccharomyces cerevisiae 57692 R-SCE-6784224 https://reactome.org/PathwayBrowser/#/R-SCE-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Saccharomyces cerevisiae 57692 R-SCE-70670 https://reactome.org/PathwayBrowser/#/R-SCE-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Saccharomyces cerevisiae 57692 R-SCE-71401 https://reactome.org/PathwayBrowser/#/R-SCE-71401 OGDH dimer decarboxylates 2-OG IEA Saccharomyces cerevisiae 57692 R-SCE-71682 https://reactome.org/PathwayBrowser/#/R-SCE-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 57692 R-SCE-880007 https://reactome.org/PathwayBrowser/#/R-SCE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Saccharomyces cerevisiae 57692 R-SCE-8955817 https://reactome.org/PathwayBrowser/#/R-SCE-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Saccharomyces cerevisiae 57692 R-SCE-9853499 https://reactome.org/PathwayBrowser/#/R-SCE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 57692 R-SCE-9853512 https://reactome.org/PathwayBrowser/#/R-SCE-9853512 DLST transfers succinyl to CoA IEA Saccharomyces cerevisiae 57692 R-SCE-9854672 https://reactome.org/PathwayBrowser/#/R-SCE-9854672 FAD attaches to SDHA IEA Saccharomyces cerevisiae 57692 R-SCE-9861616 https://reactome.org/PathwayBrowser/#/R-SCE-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 57692 R-SCE-9861667 https://reactome.org/PathwayBrowser/#/R-SCE-9861667 DLAT trimer transfers acetyl to CoA IEA Saccharomyces cerevisiae 57692 R-SCE-9861734 https://reactome.org/PathwayBrowser/#/R-SCE-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Saccharomyces cerevisiae 57692 R-SPO-1497784 https://reactome.org/PathwayBrowser/#/R-SPO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Schizosaccharomyces pombe 57692 R-SPO-1497796 https://reactome.org/PathwayBrowser/#/R-SPO-1497796 BH2 binding can lead to eNOS uncoupling IEA Schizosaccharomyces pombe 57692 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 57692 R-SPO-169260 https://reactome.org/PathwayBrowser/#/R-SPO-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Schizosaccharomyces pombe 57692 R-SPO-169270 https://reactome.org/PathwayBrowser/#/R-SPO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Schizosaccharomyces pombe 57692 R-SPO-188467 https://reactome.org/PathwayBrowser/#/R-SPO-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Schizosaccharomyces pombe 57692 R-SPO-189423 https://reactome.org/PathwayBrowser/#/R-SPO-189423 PPO oxidises PPGEN9 to PRIN9 IEA Schizosaccharomyces pombe 57692 R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 57692 R-SPO-196929 https://reactome.org/PathwayBrowser/#/R-SPO-196929 FLAD1 phosphorylates FMN IEA Schizosaccharomyces pombe 57692 R-SPO-196955 https://reactome.org/PathwayBrowser/#/R-SPO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Schizosaccharomyces pombe 57692 R-SPO-198824 https://reactome.org/PathwayBrowser/#/R-SPO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Schizosaccharomyces pombe 57692 R-SPO-202111 https://reactome.org/PathwayBrowser/#/R-SPO-202111 AKT1 phosphorylates eNOS IEA Schizosaccharomyces pombe 57692 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 57692 R-SPO-202132 https://reactome.org/PathwayBrowser/#/R-SPO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Schizosaccharomyces pombe 57692 R-SPO-202137 https://reactome.org/PathwayBrowser/#/R-SPO-202137 AKT1 binds eNOS complex via HSP90 IEA Schizosaccharomyces pombe 57692 R-SPO-203613 https://reactome.org/PathwayBrowser/#/R-SPO-203613 depalmitoylation of eNOS IEA Schizosaccharomyces pombe 57692 R-SPO-203700 https://reactome.org/PathwayBrowser/#/R-SPO-203700 eNOS translocation from Golgi to Caveolae IEA Schizosaccharomyces pombe 57692 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 57692 R-SPO-2162186 https://reactome.org/PathwayBrowser/#/R-SPO-2162186 COQ3 methylates DeMQ10H2 IEA Schizosaccharomyces pombe 57692 R-SPO-2162188 https://reactome.org/PathwayBrowser/#/R-SPO-2162188 COQ5 methylates MDMQ10H2 IEA Schizosaccharomyces pombe 57692 R-SPO-2162193 https://reactome.org/PathwayBrowser/#/R-SPO-2162193 COQ3 methylates DHDB IEA Schizosaccharomyces pombe 57692 R-SPO-2162194 https://reactome.org/PathwayBrowser/#/R-SPO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Schizosaccharomyces pombe 57692 R-SPO-2395517 https://reactome.org/PathwayBrowser/#/R-SPO-2395517 NADPH transfers electrons to FDXR IEA Schizosaccharomyces pombe 57692 R-SPO-3323079 https://reactome.org/PathwayBrowser/#/R-SPO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 57692 R-SPO-389821 https://reactome.org/PathwayBrowser/#/R-SPO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Schizosaccharomyces pombe 57692 R-SPO-5694018 https://reactome.org/PathwayBrowser/#/R-SPO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Schizosaccharomyces pombe 57692 R-SPO-6784224 https://reactome.org/PathwayBrowser/#/R-SPO-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Schizosaccharomyces pombe 57692 R-SPO-6810076 https://reactome.org/PathwayBrowser/#/R-SPO-6810076 DDO oxidizes D-Asp to OA IEA Schizosaccharomyces pombe 57692 R-SPO-70670 https://reactome.org/PathwayBrowser/#/R-SPO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Schizosaccharomyces pombe 57692 R-SPO-71401 https://reactome.org/PathwayBrowser/#/R-SPO-71401 OGDH dimer decarboxylates 2-OG IEA Schizosaccharomyces pombe 57692 R-SPO-71682 https://reactome.org/PathwayBrowser/#/R-SPO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 57692 R-SPO-880007 https://reactome.org/PathwayBrowser/#/R-SPO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Schizosaccharomyces pombe 57692 R-SPO-8955817 https://reactome.org/PathwayBrowser/#/R-SPO-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Schizosaccharomyces pombe 57692 R-SPO-9853499 https://reactome.org/PathwayBrowser/#/R-SPO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 57692 R-SPO-9853512 https://reactome.org/PathwayBrowser/#/R-SPO-9853512 DLST transfers succinyl to CoA IEA Schizosaccharomyces pombe 57692 R-SPO-9854672 https://reactome.org/PathwayBrowser/#/R-SPO-9854672 FAD attaches to SDHA IEA Schizosaccharomyces pombe 57692 R-SPO-9861616 https://reactome.org/PathwayBrowser/#/R-SPO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 57692 R-SPO-9861667 https://reactome.org/PathwayBrowser/#/R-SPO-9861667 DLAT trimer transfers acetyl to CoA IEA Schizosaccharomyces pombe 57692 R-SPO-9861734 https://reactome.org/PathwayBrowser/#/R-SPO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Schizosaccharomyces pombe 57692 R-SSC-109341 https://reactome.org/PathwayBrowser/#/R-SSC-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Sus scrofa 57692 R-SSC-1222376 https://reactome.org/PathwayBrowser/#/R-SSC-1222376 NOX2 generates superoxide from oxygen IEA Sus scrofa 57692 R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 57692 R-SSC-141186 https://reactome.org/PathwayBrowser/#/R-SSC-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Sus scrofa 57692 R-SSC-141200 https://reactome.org/PathwayBrowser/#/R-SSC-141200 MAOB:FAD oxidatively deaminates of PEA IEA Sus scrofa 57692 R-SSC-141202 https://reactome.org/PathwayBrowser/#/R-SSC-141202 MAOB:FAD oxidatively deaminates TYR IEA Sus scrofa 57692 R-SSC-141348 https://reactome.org/PathwayBrowser/#/R-SSC-141348 PAO:FAD oxidises NASPM to PTCN IEA Sus scrofa 57692 R-SSC-141351 https://reactome.org/PathwayBrowser/#/R-SSC-141351 PAOX:FAD oxidises NASPN to SPM IEA Sus scrofa 57692 R-SSC-1497784 https://reactome.org/PathwayBrowser/#/R-SSC-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Sus scrofa 57692 R-SSC-1497796 https://reactome.org/PathwayBrowser/#/R-SSC-1497796 BH2 binding can lead to eNOS uncoupling IEA Sus scrofa 57692 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 57692 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Sus scrofa 57692 R-SSC-1655453 https://reactome.org/PathwayBrowser/#/R-SSC-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Sus scrofa 57692 R-SSC-169260 https://reactome.org/PathwayBrowser/#/R-SSC-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Sus scrofa 57692 R-SSC-169270 https://reactome.org/PathwayBrowser/#/R-SSC-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Sus scrofa 57692 R-SSC-174374 https://reactome.org/PathwayBrowser/#/R-SSC-174374 MTR transfers CH3 from MeCbl to HCYS IEA Sus scrofa 57692 R-SSC-188467 https://reactome.org/PathwayBrowser/#/R-SSC-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Sus scrofa 57692 R-SSC-189423 https://reactome.org/PathwayBrowser/#/R-SSC-189423 PPO oxidises PPGEN9 to PRIN9 IEA Sus scrofa 57692 R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 57692 R-SSC-192335 https://reactome.org/PathwayBrowser/#/R-SSC-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Sus scrofa 57692 R-SSC-193369 https://reactome.org/PathwayBrowser/#/R-SSC-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Sus scrofa 57692 R-SSC-196929 https://reactome.org/PathwayBrowser/#/R-SSC-196929 FLAD1 phosphorylates FMN IEA Sus scrofa 57692 R-SSC-196955 https://reactome.org/PathwayBrowser/#/R-SSC-196955 2xENPP1 hydrolyzes FAD to FMN IEA Sus scrofa 57692 R-SSC-198824 https://reactome.org/PathwayBrowser/#/R-SSC-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Sus scrofa 57692 R-SSC-202110 https://reactome.org/PathwayBrowser/#/R-SSC-202110 eNOS:Caveolin-1 complex binds to CaM IEA Sus scrofa 57692 R-SSC-202111 https://reactome.org/PathwayBrowser/#/R-SSC-202111 AKT1 phosphorylates eNOS IEA Sus scrofa 57692 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 57692 R-SSC-202129 https://reactome.org/PathwayBrowser/#/R-SSC-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Sus scrofa 57692 R-SSC-202132 https://reactome.org/PathwayBrowser/#/R-SSC-202132 depalmitoylated eNOS translocates from plasma membrane IEA Sus scrofa 57692 R-SSC-202144 https://reactome.org/PathwayBrowser/#/R-SSC-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Sus scrofa 57692 R-SSC-203553 https://reactome.org/PathwayBrowser/#/R-SSC-203553 eNOS binds NOSIP IEA Sus scrofa 57692 R-SSC-203565 https://reactome.org/PathwayBrowser/#/R-SSC-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Sus scrofa 57692 R-SSC-203613 https://reactome.org/PathwayBrowser/#/R-SSC-203613 depalmitoylation of eNOS IEA Sus scrofa 57692 R-SSC-203625 https://reactome.org/PathwayBrowser/#/R-SSC-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Sus scrofa 57692 R-SSC-203662 https://reactome.org/PathwayBrowser/#/R-SSC-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Sus scrofa 57692 R-SSC-203680 https://reactome.org/PathwayBrowser/#/R-SSC-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Sus scrofa 57692 R-SSC-203700 https://reactome.org/PathwayBrowser/#/R-SSC-203700 eNOS translocation from Golgi to Caveolae IEA Sus scrofa 57692 R-SSC-203712 https://reactome.org/PathwayBrowser/#/R-SSC-203712 eNOS associates with Caveolin-1 IEA Sus scrofa 57692 R-SSC-203716 https://reactome.org/PathwayBrowser/#/R-SSC-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Sus scrofa 57692 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 57692 R-SSC-204169 https://reactome.org/PathwayBrowser/#/R-SSC-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Sus scrofa 57692 R-SSC-2066787 https://reactome.org/PathwayBrowser/#/R-SSC-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Sus scrofa 57692 R-SSC-2160492 https://reactome.org/PathwayBrowser/#/R-SSC-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Sus scrofa 57692 R-SSC-2162186 https://reactome.org/PathwayBrowser/#/R-SSC-2162186 COQ3 methylates DeMQ10H2 IEA Sus scrofa 57692 R-SSC-2162188 https://reactome.org/PathwayBrowser/#/R-SSC-2162188 COQ5 methylates MDMQ10H2 IEA Sus scrofa 57692 R-SSC-2162193 https://reactome.org/PathwayBrowser/#/R-SSC-2162193 COQ3 methylates DHDB IEA Sus scrofa 57692 R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa 57692 R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 57692 R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 57692 R-SSC-2395512 https://reactome.org/PathwayBrowser/#/R-SSC-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Sus scrofa 57692 R-SSC-2395517 https://reactome.org/PathwayBrowser/#/R-SSC-2395517 NADPH transfers electrons to FDXR IEA Sus scrofa 57692 R-SSC-3149518 https://reactome.org/PathwayBrowser/#/R-SSC-3149518 MTRR reduces cob(II)alamin to meCbl IEA Sus scrofa 57692 R-SSC-3149539 https://reactome.org/PathwayBrowser/#/R-SSC-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Sus scrofa 57692 R-SSC-3159253 https://reactome.org/PathwayBrowser/#/R-SSC-3159253 MMAB adenosylates cob(I)alamin IEA Sus scrofa 57692 R-SSC-3165230 https://reactome.org/PathwayBrowser/#/R-SSC-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Sus scrofa 57692 R-SSC-3204311 https://reactome.org/PathwayBrowser/#/R-SSC-3204311 AOX1 oxidises PXL to PDXate IEA Sus scrofa 57692 R-SSC-3204318 https://reactome.org/PathwayBrowser/#/R-SSC-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Sus scrofa 57692 R-SSC-3323079 https://reactome.org/PathwayBrowser/#/R-SSC-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 57692 R-SSC-374909 https://reactome.org/PathwayBrowser/#/R-SSC-374909 Catabolism of Noradrenaline IEA Sus scrofa 57692 R-SSC-379382 https://reactome.org/PathwayBrowser/#/R-SSC-379382 MAOA:FAD deaminates DA to DOPAC IEA Sus scrofa 57692 R-SSC-379395 https://reactome.org/PathwayBrowser/#/R-SSC-379395 MAOA:FAD deaminates 3MT to HVA IEA Sus scrofa 57692 R-SSC-389821 https://reactome.org/PathwayBrowser/#/R-SSC-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Sus scrofa 57692 R-SSC-389889 https://reactome.org/PathwayBrowser/#/R-SSC-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Sus scrofa 57692 R-SSC-389891 https://reactome.org/PathwayBrowser/#/R-SSC-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Sus scrofa 57692 R-SSC-390256 https://reactome.org/PathwayBrowser/#/R-SSC-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Sus scrofa 57692 R-SSC-390427 https://reactome.org/PathwayBrowser/#/R-SSC-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Sus scrofa 57692 R-SSC-5218827 https://reactome.org/PathwayBrowser/#/R-SSC-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Sus scrofa 57692 R-SSC-5218841 https://reactome.org/PathwayBrowser/#/R-SSC-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Sus scrofa 57692 R-SSC-5693148 https://reactome.org/PathwayBrowser/#/R-SSC-5693148 BCKDK phosphorylates BCKDH IEA Sus scrofa 57692 R-SSC-5693153 https://reactome.org/PathwayBrowser/#/R-SSC-5693153 PPM1K dephosphorylates p-BCKDH IEA Sus scrofa 57692 R-SSC-5694018 https://reactome.org/PathwayBrowser/#/R-SSC-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Sus scrofa 57692 R-SSC-5695980 https://reactome.org/PathwayBrowser/#/R-SSC-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Sus scrofa 57692 R-SSC-5695989 https://reactome.org/PathwayBrowser/#/R-SSC-5695989 ACAD11 dehydrogenates BH-CoA IEA Sus scrofa 57692 R-SSC-6784224 https://reactome.org/PathwayBrowser/#/R-SSC-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Sus scrofa 57692 R-SSC-6797653 https://reactome.org/PathwayBrowser/#/R-SSC-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Sus scrofa 57692 R-SSC-6797913 https://reactome.org/PathwayBrowser/#/R-SSC-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Sus scrofa 57692 R-SSC-6799178 https://reactome.org/PathwayBrowser/#/R-SSC-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Sus scrofa 57692 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa 57692 R-SSC-6799191 https://reactome.org/PathwayBrowser/#/R-SSC-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Sus scrofa 57692 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa 57692 R-SSC-6799197 https://reactome.org/PathwayBrowser/#/R-SSC-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Sus scrofa 57692 R-SSC-6799202 https://reactome.org/PathwayBrowser/#/R-SSC-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Sus scrofa 57692 R-SSC-6799203 https://reactome.org/PathwayBrowser/#/R-SSC-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Sus scrofa 57692 R-SSC-6800868 https://reactome.org/PathwayBrowser/#/R-SSC-6800868 NDUF subunits bind to form the IP subcomplex IEA Sus scrofa 57692 R-SSC-6810076 https://reactome.org/PathwayBrowser/#/R-SSC-6810076 DDO oxidizes D-Asp to OA IEA Sus scrofa 57692 R-SSC-70670 https://reactome.org/PathwayBrowser/#/R-SSC-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Sus scrofa 57692 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 57692 R-SSC-70745 https://reactome.org/PathwayBrowser/#/R-SSC-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Sus scrofa 57692 R-SSC-70800 https://reactome.org/PathwayBrowser/#/R-SSC-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Sus scrofa 57692 R-SSC-70859 https://reactome.org/PathwayBrowser/#/R-SSC-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Sus scrofa 57692 R-SSC-71037 https://reactome.org/PathwayBrowser/#/R-SSC-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Sus scrofa 57692 R-SSC-71046 https://reactome.org/PathwayBrowser/#/R-SSC-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Sus scrofa 57692 R-SSC-71401 https://reactome.org/PathwayBrowser/#/R-SSC-71401 OGDH dimer decarboxylates 2-OG IEA Sus scrofa 57692 R-SSC-71682 https://reactome.org/PathwayBrowser/#/R-SSC-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 57692 R-SSC-73585 https://reactome.org/PathwayBrowser/#/R-SSC-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Sus scrofa 57692 R-SSC-73616 https://reactome.org/PathwayBrowser/#/R-SSC-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Sus scrofa 57692 R-SSC-74247 https://reactome.org/PathwayBrowser/#/R-SSC-74247 XDH oxidizes hypoxanthine to form xanthine IEA Sus scrofa 57692 R-SSC-74258 https://reactome.org/PathwayBrowser/#/R-SSC-74258 XDH oxidizes xanthine to form urate IEA Sus scrofa 57692 R-SSC-75879 https://reactome.org/PathwayBrowser/#/R-SSC-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Sus scrofa 57692 R-SSC-77263 https://reactome.org/PathwayBrowser/#/R-SSC-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Sus scrofa 57692 R-SSC-77274 https://reactome.org/PathwayBrowser/#/R-SSC-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Sus scrofa 57692 R-SSC-77299 https://reactome.org/PathwayBrowser/#/R-SSC-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Sus scrofa 57692 R-SSC-77319 https://reactome.org/PathwayBrowser/#/R-SSC-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Sus scrofa 57692 R-SSC-77327 https://reactome.org/PathwayBrowser/#/R-SSC-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Sus scrofa 57692 R-SSC-77338 https://reactome.org/PathwayBrowser/#/R-SSC-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Sus scrofa 57692 R-SSC-77345 https://reactome.org/PathwayBrowser/#/R-SSC-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Sus scrofa 57692 R-SSC-880007 https://reactome.org/PathwayBrowser/#/R-SSC-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa 57692 R-SSC-880050 https://reactome.org/PathwayBrowser/#/R-SSC-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa 57692 R-SSC-8865107 https://reactome.org/PathwayBrowser/#/R-SSC-8865107 MICAL1 produces NADP+, H2O2 IEA Sus scrofa 57692 R-SSC-8936519 https://reactome.org/PathwayBrowser/#/R-SSC-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Sus scrofa 57692 R-SSC-8955817 https://reactome.org/PathwayBrowser/#/R-SSC-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Sus scrofa 57692 R-SSC-8956458 https://reactome.org/PathwayBrowser/#/R-SSC-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Sus scrofa 57692 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa 57692 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa 57692 R-SSC-917811 https://reactome.org/PathwayBrowser/#/R-SSC-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Sus scrofa 57692 R-SSC-9677917 https://reactome.org/PathwayBrowser/#/R-SSC-9677917 MAOA inhibitors bind MAOA:FAD IEA Sus scrofa 57692 R-SSC-9677929 https://reactome.org/PathwayBrowser/#/R-SSC-9677929 MAOB inhibitors bind MAOB:FAD IEA Sus scrofa 57692 R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 57692 R-SSC-9727349 https://reactome.org/PathwayBrowser/#/R-SSC-9727349 XDH dehydrogenates xanthine to form urate IEA Sus scrofa 57692 R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 57692 R-SSC-9853499 https://reactome.org/PathwayBrowser/#/R-SSC-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 57692 R-SSC-9853512 https://reactome.org/PathwayBrowser/#/R-SSC-9853512 DLST transfers succinyl to CoA IEA Sus scrofa 57692 R-SSC-9854672 https://reactome.org/PathwayBrowser/#/R-SSC-9854672 FAD attaches to SDHA IEA Sus scrofa 57692 R-SSC-9861616 https://reactome.org/PathwayBrowser/#/R-SSC-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 57692 R-SSC-9861667 https://reactome.org/PathwayBrowser/#/R-SSC-9861667 DLAT trimer transfers acetyl to CoA IEA Sus scrofa 57692 R-SSC-9861734 https://reactome.org/PathwayBrowser/#/R-SSC-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Sus scrofa 57692 R-XTR-1222376 https://reactome.org/PathwayBrowser/#/R-XTR-1222376 NOX2 generates superoxide from oxygen IEA Xenopus tropicalis 57692 R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 57692 R-XTR-141200 https://reactome.org/PathwayBrowser/#/R-XTR-141200 MAOB:FAD oxidatively deaminates of PEA IEA Xenopus tropicalis 57692 R-XTR-141202 https://reactome.org/PathwayBrowser/#/R-XTR-141202 MAOB:FAD oxidatively deaminates TYR IEA Xenopus tropicalis 57692 R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Xenopus tropicalis 57692 R-XTR-1655453 https://reactome.org/PathwayBrowser/#/R-XTR-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Xenopus tropicalis 57692 R-XTR-169260 https://reactome.org/PathwayBrowser/#/R-XTR-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Xenopus tropicalis 57692 R-XTR-169270 https://reactome.org/PathwayBrowser/#/R-XTR-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Xenopus tropicalis 57692 R-XTR-188467 https://reactome.org/PathwayBrowser/#/R-XTR-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Xenopus tropicalis 57692 R-XTR-189423 https://reactome.org/PathwayBrowser/#/R-XTR-189423 PPO oxidises PPGEN9 to PRIN9 IEA Xenopus tropicalis 57692 R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 57692 R-XTR-192335 https://reactome.org/PathwayBrowser/#/R-XTR-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Xenopus tropicalis 57692 R-XTR-193369 https://reactome.org/PathwayBrowser/#/R-XTR-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Xenopus tropicalis 57692 R-XTR-196955 https://reactome.org/PathwayBrowser/#/R-XTR-196955 2xENPP1 hydrolyzes FAD to FMN IEA Xenopus tropicalis 57692 R-XTR-198824 https://reactome.org/PathwayBrowser/#/R-XTR-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Xenopus tropicalis 57692 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 57692 R-XTR-2066787 https://reactome.org/PathwayBrowser/#/R-XTR-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Xenopus tropicalis 57692 R-XTR-2160492 https://reactome.org/PathwayBrowser/#/R-XTR-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Xenopus tropicalis 57692 R-XTR-2162186 https://reactome.org/PathwayBrowser/#/R-XTR-2162186 COQ3 methylates DeMQ10H2 IEA Xenopus tropicalis 57692 R-XTR-2162188 https://reactome.org/PathwayBrowser/#/R-XTR-2162188 COQ5 methylates MDMQ10H2 IEA Xenopus tropicalis 57692 R-XTR-2162193 https://reactome.org/PathwayBrowser/#/R-XTR-2162193 COQ3 methylates DHDB IEA Xenopus tropicalis 57692 R-XTR-2162194 https://reactome.org/PathwayBrowser/#/R-XTR-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Xenopus tropicalis 57692 R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 57692 R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 57692 R-XTR-2395512 https://reactome.org/PathwayBrowser/#/R-XTR-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Xenopus tropicalis 57692 R-XTR-2395517 https://reactome.org/PathwayBrowser/#/R-XTR-2395517 NADPH transfers electrons to FDXR IEA Xenopus tropicalis 57692 R-XTR-3159253 https://reactome.org/PathwayBrowser/#/R-XTR-3159253 MMAB adenosylates cob(I)alamin IEA Xenopus tropicalis 57692 R-XTR-3165230 https://reactome.org/PathwayBrowser/#/R-XTR-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Xenopus tropicalis 57692 R-XTR-3204311 https://reactome.org/PathwayBrowser/#/R-XTR-3204311 AOX1 oxidises PXL to PDXate IEA Xenopus tropicalis 57692 R-XTR-3323079 https://reactome.org/PathwayBrowser/#/R-XTR-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 57692 R-XTR-389821 https://reactome.org/PathwayBrowser/#/R-XTR-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Xenopus tropicalis 57692 R-XTR-389889 https://reactome.org/PathwayBrowser/#/R-XTR-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Xenopus tropicalis 57692 R-XTR-389891 https://reactome.org/PathwayBrowser/#/R-XTR-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Xenopus tropicalis 57692 R-XTR-390256 https://reactome.org/PathwayBrowser/#/R-XTR-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 IEA Xenopus tropicalis 57692 R-XTR-390427 https://reactome.org/PathwayBrowser/#/R-XTR-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Xenopus tropicalis 57692 R-XTR-5218827 https://reactome.org/PathwayBrowser/#/R-XTR-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Xenopus tropicalis 57692 R-XTR-5218841 https://reactome.org/PathwayBrowser/#/R-XTR-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Xenopus tropicalis 57692 R-XTR-5693148 https://reactome.org/PathwayBrowser/#/R-XTR-5693148 BCKDK phosphorylates BCKDH IEA Xenopus tropicalis 57692 R-XTR-5694018 https://reactome.org/PathwayBrowser/#/R-XTR-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Xenopus tropicalis 57692 R-XTR-5695989 https://reactome.org/PathwayBrowser/#/R-XTR-5695989 ACAD11 dehydrogenates BH-CoA IEA Xenopus tropicalis 57692 R-XTR-6784224 https://reactome.org/PathwayBrowser/#/R-XTR-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Xenopus tropicalis 57692 R-XTR-6799197 https://reactome.org/PathwayBrowser/#/R-XTR-6799197 ND4, ND5 bind the 550kDa complex to form the 815kDa complex IEA Xenopus tropicalis 57692 R-XTR-6799202 https://reactome.org/PathwayBrowser/#/R-XTR-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Xenopus tropicalis 57692 R-XTR-6799203 https://reactome.org/PathwayBrowser/#/R-XTR-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Xenopus tropicalis 57692 R-XTR-6800868 https://reactome.org/PathwayBrowser/#/R-XTR-6800868 NDUF subunits bind to form the IP subcomplex IEA Xenopus tropicalis 57692 R-XTR-70670 https://reactome.org/PathwayBrowser/#/R-XTR-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Xenopus tropicalis 57692 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 57692 R-XTR-70745 https://reactome.org/PathwayBrowser/#/R-XTR-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Xenopus tropicalis 57692 R-XTR-70800 https://reactome.org/PathwayBrowser/#/R-XTR-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Xenopus tropicalis 57692 R-XTR-70859 https://reactome.org/PathwayBrowser/#/R-XTR-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Xenopus tropicalis 57692 R-XTR-71037 https://reactome.org/PathwayBrowser/#/R-XTR-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 57692 R-XTR-71046 https://reactome.org/PathwayBrowser/#/R-XTR-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Xenopus tropicalis 57692 R-XTR-71401 https://reactome.org/PathwayBrowser/#/R-XTR-71401 OGDH dimer decarboxylates 2-OG IEA Xenopus tropicalis 57692 R-XTR-71682 https://reactome.org/PathwayBrowser/#/R-XTR-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 57692 R-XTR-73585 https://reactome.org/PathwayBrowser/#/R-XTR-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Xenopus tropicalis 57692 R-XTR-73616 https://reactome.org/PathwayBrowser/#/R-XTR-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Xenopus tropicalis 57692 R-XTR-74247 https://reactome.org/PathwayBrowser/#/R-XTR-74247 XDH oxidizes hypoxanthine to form xanthine IEA Xenopus tropicalis 57692 R-XTR-74258 https://reactome.org/PathwayBrowser/#/R-XTR-74258 XDH oxidizes xanthine to form urate IEA Xenopus tropicalis 57692 R-XTR-75879 https://reactome.org/PathwayBrowser/#/R-XTR-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Xenopus tropicalis 57692 R-XTR-77263 https://reactome.org/PathwayBrowser/#/R-XTR-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Xenopus tropicalis 57692 R-XTR-77274 https://reactome.org/PathwayBrowser/#/R-XTR-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Xenopus tropicalis 57692 R-XTR-77319 https://reactome.org/PathwayBrowser/#/R-XTR-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Xenopus tropicalis 57692 R-XTR-77327 https://reactome.org/PathwayBrowser/#/R-XTR-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Xenopus tropicalis 57692 R-XTR-880007 https://reactome.org/PathwayBrowser/#/R-XTR-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Xenopus tropicalis 57692 R-XTR-880050 https://reactome.org/PathwayBrowser/#/R-XTR-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Xenopus tropicalis 57692 R-XTR-8865107 https://reactome.org/PathwayBrowser/#/R-XTR-8865107 MICAL1 produces NADP+, H2O2 IEA Xenopus tropicalis 57692 R-XTR-8936519 https://reactome.org/PathwayBrowser/#/R-XTR-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Xenopus tropicalis 57692 R-XTR-8955817 https://reactome.org/PathwayBrowser/#/R-XTR-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Xenopus tropicalis 57692 R-XTR-8956458 https://reactome.org/PathwayBrowser/#/R-XTR-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Xenopus tropicalis 57692 R-XTR-9013145 https://reactome.org/PathwayBrowser/#/R-XTR-9013145 RAC1 binds effectors at the plasma membrane IEA Xenopus tropicalis 57692 R-XTR-9018808 https://reactome.org/PathwayBrowser/#/R-XTR-9018808 RAC3 binds effectors at the plasma membrane IEA Xenopus tropicalis 57692 R-XTR-917811 https://reactome.org/PathwayBrowser/#/R-XTR-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Xenopus tropicalis 57692 R-XTR-9677929 https://reactome.org/PathwayBrowser/#/R-XTR-9677929 MAOB inhibitors bind MAOB:FAD IEA Xenopus tropicalis 57692 R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 57692 R-XTR-9727349 https://reactome.org/PathwayBrowser/#/R-XTR-9727349 XDH dehydrogenates xanthine to form urate IEA Xenopus tropicalis 57692 R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 57692 R-XTR-9853499 https://reactome.org/PathwayBrowser/#/R-XTR-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 57692 R-XTR-9853512 https://reactome.org/PathwayBrowser/#/R-XTR-9853512 DLST transfers succinyl to CoA IEA Xenopus tropicalis 57692 R-XTR-9854672 https://reactome.org/PathwayBrowser/#/R-XTR-9854672 FAD attaches to SDHA IEA Xenopus tropicalis 57692 R-XTR-9861616 https://reactome.org/PathwayBrowser/#/R-XTR-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 57692 R-XTR-9861667 https://reactome.org/PathwayBrowser/#/R-XTR-9861667 DLAT trimer transfers acetyl to CoA IEA Xenopus tropicalis 57692 R-XTR-9861734 https://reactome.org/PathwayBrowser/#/R-XTR-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Xenopus tropicalis 57700 R-BTA-508473 https://reactome.org/PathwayBrowser/#/R-BTA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Bos taurus 57700 R-BTA-70885 https://reactome.org/PathwayBrowser/#/R-BTA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Bos taurus 57700 R-BTA-70893 https://reactome.org/PathwayBrowser/#/R-BTA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Bos taurus 57700 R-CEL-508473 https://reactome.org/PathwayBrowser/#/R-CEL-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Caenorhabditis elegans 57700 R-CEL-70885 https://reactome.org/PathwayBrowser/#/R-CEL-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Caenorhabditis elegans 57700 R-CEL-70893 https://reactome.org/PathwayBrowser/#/R-CEL-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 57700 R-CFA-508473 https://reactome.org/PathwayBrowser/#/R-CFA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Canis familiaris 57700 R-CFA-70885 https://reactome.org/PathwayBrowser/#/R-CFA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Canis familiaris 57700 R-CFA-70893 https://reactome.org/PathwayBrowser/#/R-CFA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Canis familiaris 57700 R-DDI-508473 https://reactome.org/PathwayBrowser/#/R-DDI-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Dictyostelium discoideum 57700 R-DDI-70885 https://reactome.org/PathwayBrowser/#/R-DDI-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Dictyostelium discoideum 57700 R-DDI-70893 https://reactome.org/PathwayBrowser/#/R-DDI-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 57700 R-DME-508473 https://reactome.org/PathwayBrowser/#/R-DME-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Drosophila melanogaster 57700 R-DME-70885 https://reactome.org/PathwayBrowser/#/R-DME-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Drosophila melanogaster 57700 R-DME-70893 https://reactome.org/PathwayBrowser/#/R-DME-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 57700 R-DRE-508473 https://reactome.org/PathwayBrowser/#/R-DRE-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Danio rerio 57700 R-DRE-70885 https://reactome.org/PathwayBrowser/#/R-DRE-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Danio rerio 57700 R-DRE-70893 https://reactome.org/PathwayBrowser/#/R-DRE-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Danio rerio 57700 R-GGA-508473 https://reactome.org/PathwayBrowser/#/R-GGA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Gallus gallus 57700 R-GGA-70885 https://reactome.org/PathwayBrowser/#/R-GGA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Gallus gallus 57700 R-GGA-70893 https://reactome.org/PathwayBrowser/#/R-GGA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Gallus gallus 57700 R-HSA-508473 https://reactome.org/PathwayBrowser/#/R-HSA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ TAS Homo sapiens 57700 R-HSA-70885 https://reactome.org/PathwayBrowser/#/R-HSA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ TAS Homo sapiens 57700 R-HSA-70893 https://reactome.org/PathwayBrowser/#/R-HSA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ TAS Homo sapiens 57700 R-HSA-909780 https://reactome.org/PathwayBrowser/#/R-HSA-909780 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine IEA Homo sapiens 57700 R-MMU-508473 https://reactome.org/PathwayBrowser/#/R-MMU-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Mus musculus 57700 R-MMU-70885 https://reactome.org/PathwayBrowser/#/R-MMU-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Mus musculus 57700 R-MMU-70893 https://reactome.org/PathwayBrowser/#/R-MMU-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Mus musculus 57700 R-RNO-508473 https://reactome.org/PathwayBrowser/#/R-RNO-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Rattus norvegicus 57700 R-RNO-70885 https://reactome.org/PathwayBrowser/#/R-RNO-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Rattus norvegicus 57700 R-RNO-70893 https://reactome.org/PathwayBrowser/#/R-RNO-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 57700 R-RNO-909775 https://reactome.org/PathwayBrowser/#/R-RNO-909775 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine TAS Rattus norvegicus 57700 R-SSC-508473 https://reactome.org/PathwayBrowser/#/R-SSC-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Sus scrofa 57700 R-SSC-70885 https://reactome.org/PathwayBrowser/#/R-SSC-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Sus scrofa 57700 R-SSC-70893 https://reactome.org/PathwayBrowser/#/R-SSC-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Sus scrofa 57700 R-XTR-508473 https://reactome.org/PathwayBrowser/#/R-XTR-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Xenopus tropicalis 57700 R-XTR-70885 https://reactome.org/PathwayBrowser/#/R-XTR-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Xenopus tropicalis 57700 R-XTR-70893 https://reactome.org/PathwayBrowser/#/R-XTR-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 57701 R-MTU-964884 https://reactome.org/PathwayBrowser/#/R-MTU-964884 Dephosphorylation of EPSP yields chorismate TAS Mycobacterium tuberculosis 57701 R-MTU-964886 https://reactome.org/PathwayBrowser/#/R-MTU-964886 EPSP from shikimate 3-phosphate TAS Mycobacterium tuberculosis 57705 R-BTA-162730 https://reactome.org/PathwayBrowser/#/R-BTA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Bos taurus 57705 R-BTA-174368 https://reactome.org/PathwayBrowser/#/R-BTA-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Bos taurus 57705 R-BTA-2022851 https://reactome.org/PathwayBrowser/#/R-BTA-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Bos taurus 57705 R-BTA-2022919 https://reactome.org/PathwayBrowser/#/R-BTA-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Bos taurus 57705 R-BTA-2025724 https://reactome.org/PathwayBrowser/#/R-BTA-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Bos taurus 57705 R-BTA-4085021 https://reactome.org/PathwayBrowser/#/R-BTA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Bos taurus 57705 R-BTA-446191 https://reactome.org/PathwayBrowser/#/R-BTA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Bos taurus 57705 R-BTA-446204 https://reactome.org/PathwayBrowser/#/R-BTA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Bos taurus 57705 R-BTA-446207 https://reactome.org/PathwayBrowser/#/R-BTA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Bos taurus 57705 R-BTA-5617037 https://reactome.org/PathwayBrowser/#/R-BTA-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Bos taurus 57705 R-BTA-5694487 https://reactome.org/PathwayBrowser/#/R-BTA-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Bos taurus 57705 R-BTA-741450 https://reactome.org/PathwayBrowser/#/R-BTA-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Bos taurus 57705 R-BTA-742354 https://reactome.org/PathwayBrowser/#/R-BTA-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Bos taurus 57705 R-BTA-744231 https://reactome.org/PathwayBrowser/#/R-BTA-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Bos taurus 57705 R-BTA-8879117 https://reactome.org/PathwayBrowser/#/R-BTA-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Bos taurus 57705 R-BTA-914005 https://reactome.org/PathwayBrowser/#/R-BTA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Bos taurus 57705 R-BTA-914008 https://reactome.org/PathwayBrowser/#/R-BTA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Bos taurus 57705 R-BTA-914010 https://reactome.org/PathwayBrowser/#/R-BTA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Bos taurus 57705 R-BTA-914012 https://reactome.org/PathwayBrowser/#/R-BTA-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Bos taurus 57705 R-BTA-914018 https://reactome.org/PathwayBrowser/#/R-BTA-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Bos taurus 57705 R-BTA-964768 https://reactome.org/PathwayBrowser/#/R-BTA-964768 Addition of GlcNAc to the glycan on the A arm IEA Bos taurus 57705 R-BTA-9687828 https://reactome.org/PathwayBrowser/#/R-BTA-9687828 O-GlcNAcylation of RIPK3 (TLR4 signaling) IEA Bos taurus 57705 R-BTA-975829 https://reactome.org/PathwayBrowser/#/R-BTA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Bos taurus 57705 R-BTA-975903 https://reactome.org/PathwayBrowser/#/R-BTA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Bos taurus 57705 R-BTA-975916 https://reactome.org/PathwayBrowser/#/R-BTA-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Bos taurus 57705 R-BTA-975926 https://reactome.org/PathwayBrowser/#/R-BTA-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Bos taurus 57705 R-BTA-9846501 https://reactome.org/PathwayBrowser/#/R-BTA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Bos taurus 57705 R-CEL-174368 https://reactome.org/PathwayBrowser/#/R-CEL-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Caenorhabditis elegans 57705 R-CEL-446191 https://reactome.org/PathwayBrowser/#/R-CEL-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Caenorhabditis elegans 57705 R-CEL-446204 https://reactome.org/PathwayBrowser/#/R-CEL-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Caenorhabditis elegans 57705 R-CEL-446207 https://reactome.org/PathwayBrowser/#/R-CEL-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Caenorhabditis elegans 57705 R-CEL-741450 https://reactome.org/PathwayBrowser/#/R-CEL-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Caenorhabditis elegans 57705 R-CEL-742354 https://reactome.org/PathwayBrowser/#/R-CEL-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Caenorhabditis elegans 57705 R-CEL-744231 https://reactome.org/PathwayBrowser/#/R-CEL-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Caenorhabditis elegans 57705 R-CEL-914005 https://reactome.org/PathwayBrowser/#/R-CEL-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Caenorhabditis elegans 57705 R-CEL-914008 https://reactome.org/PathwayBrowser/#/R-CEL-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Caenorhabditis elegans 57705 R-CEL-914012 https://reactome.org/PathwayBrowser/#/R-CEL-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Caenorhabditis elegans 57705 R-CEL-914018 https://reactome.org/PathwayBrowser/#/R-CEL-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Caenorhabditis elegans 57705 R-CEL-964768 https://reactome.org/PathwayBrowser/#/R-CEL-964768 Addition of GlcNAc to the glycan on the A arm IEA Caenorhabditis elegans 57705 R-CEL-975829 https://reactome.org/PathwayBrowser/#/R-CEL-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Caenorhabditis elegans 57705 R-CEL-975916 https://reactome.org/PathwayBrowser/#/R-CEL-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Caenorhabditis elegans 57705 R-CFA-174368 https://reactome.org/PathwayBrowser/#/R-CFA-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Canis familiaris 57705 R-CFA-2022851 https://reactome.org/PathwayBrowser/#/R-CFA-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Canis familiaris 57705 R-CFA-2022919 https://reactome.org/PathwayBrowser/#/R-CFA-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Canis familiaris 57705 R-CFA-2025724 https://reactome.org/PathwayBrowser/#/R-CFA-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Canis familiaris 57705 R-CFA-4085021 https://reactome.org/PathwayBrowser/#/R-CFA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Canis familiaris 57705 R-CFA-446191 https://reactome.org/PathwayBrowser/#/R-CFA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Canis familiaris 57705 R-CFA-446204 https://reactome.org/PathwayBrowser/#/R-CFA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Canis familiaris 57705 R-CFA-446207 https://reactome.org/PathwayBrowser/#/R-CFA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Canis familiaris 57705 R-CFA-5617037 https://reactome.org/PathwayBrowser/#/R-CFA-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Canis familiaris 57705 R-CFA-5694487 https://reactome.org/PathwayBrowser/#/R-CFA-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Canis familiaris 57705 R-CFA-741450 https://reactome.org/PathwayBrowser/#/R-CFA-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Canis familiaris 57705 R-CFA-742354 https://reactome.org/PathwayBrowser/#/R-CFA-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Canis familiaris 57705 R-CFA-744231 https://reactome.org/PathwayBrowser/#/R-CFA-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Canis familiaris 57705 R-CFA-8879117 https://reactome.org/PathwayBrowser/#/R-CFA-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Canis familiaris 57705 R-CFA-914005 https://reactome.org/PathwayBrowser/#/R-CFA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Canis familiaris 57705 R-CFA-914008 https://reactome.org/PathwayBrowser/#/R-CFA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Canis familiaris 57705 R-CFA-914010 https://reactome.org/PathwayBrowser/#/R-CFA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Canis familiaris 57705 R-CFA-914012 https://reactome.org/PathwayBrowser/#/R-CFA-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Canis familiaris 57705 R-CFA-914018 https://reactome.org/PathwayBrowser/#/R-CFA-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Canis familiaris 57705 R-CFA-9687828 https://reactome.org/PathwayBrowser/#/R-CFA-9687828 O-GlcNAcylation of RIPK3 (TLR4 signaling) IEA Canis familiaris 57705 R-CFA-975829 https://reactome.org/PathwayBrowser/#/R-CFA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Canis familiaris 57705 R-CFA-975903 https://reactome.org/PathwayBrowser/#/R-CFA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Canis familiaris 57705 R-CFA-975916 https://reactome.org/PathwayBrowser/#/R-CFA-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Canis familiaris 57705 R-DDI-174368 https://reactome.org/PathwayBrowser/#/R-DDI-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Dictyostelium discoideum 57705 R-DDI-446191 https://reactome.org/PathwayBrowser/#/R-DDI-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Dictyostelium discoideum 57705 R-DDI-446204 https://reactome.org/PathwayBrowser/#/R-DDI-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Dictyostelium discoideum 57705 R-DDI-742354 https://reactome.org/PathwayBrowser/#/R-DDI-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Dictyostelium discoideum 57705 R-DDI-744231 https://reactome.org/PathwayBrowser/#/R-DDI-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Dictyostelium discoideum 57705 R-DDI-914005 https://reactome.org/PathwayBrowser/#/R-DDI-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Dictyostelium discoideum 57705 R-DDI-914008 https://reactome.org/PathwayBrowser/#/R-DDI-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Dictyostelium discoideum 57705 R-DDI-964768 https://reactome.org/PathwayBrowser/#/R-DDI-964768 Addition of GlcNAc to the glycan on the A arm IEA Dictyostelium discoideum 57705 R-DDI-975926 https://reactome.org/PathwayBrowser/#/R-DDI-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Dictyostelium discoideum 57705 R-DME-174368 https://reactome.org/PathwayBrowser/#/R-DME-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Drosophila melanogaster 57705 R-DME-2022851 https://reactome.org/PathwayBrowser/#/R-DME-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Drosophila melanogaster 57705 R-DME-2022919 https://reactome.org/PathwayBrowser/#/R-DME-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Drosophila melanogaster 57705 R-DME-2025724 https://reactome.org/PathwayBrowser/#/R-DME-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Drosophila melanogaster 57705 R-DME-446191 https://reactome.org/PathwayBrowser/#/R-DME-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Drosophila melanogaster 57705 R-DME-446204 https://reactome.org/PathwayBrowser/#/R-DME-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Drosophila melanogaster 57705 R-DME-446207 https://reactome.org/PathwayBrowser/#/R-DME-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Drosophila melanogaster 57705 R-DME-5694487 https://reactome.org/PathwayBrowser/#/R-DME-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Drosophila melanogaster 57705 R-DME-742354 https://reactome.org/PathwayBrowser/#/R-DME-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Drosophila melanogaster 57705 R-DME-744231 https://reactome.org/PathwayBrowser/#/R-DME-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Drosophila melanogaster 57705 R-DME-914005 https://reactome.org/PathwayBrowser/#/R-DME-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Drosophila melanogaster 57705 R-DME-914008 https://reactome.org/PathwayBrowser/#/R-DME-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Drosophila melanogaster 57705 R-DME-914010 https://reactome.org/PathwayBrowser/#/R-DME-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Drosophila melanogaster 57705 R-DME-964768 https://reactome.org/PathwayBrowser/#/R-DME-964768 Addition of GlcNAc to the glycan on the A arm IEA Drosophila melanogaster 57705 R-DME-975829 https://reactome.org/PathwayBrowser/#/R-DME-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Drosophila melanogaster 57705 R-DME-975903 https://reactome.org/PathwayBrowser/#/R-DME-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Drosophila melanogaster 57705 R-DME-975926 https://reactome.org/PathwayBrowser/#/R-DME-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Drosophila melanogaster 57705 R-DME-9846501 https://reactome.org/PathwayBrowser/#/R-DME-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Drosophila melanogaster 57705 R-DRE-174368 https://reactome.org/PathwayBrowser/#/R-DRE-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Danio rerio 57705 R-DRE-2022851 https://reactome.org/PathwayBrowser/#/R-DRE-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Danio rerio 57705 R-DRE-2022919 https://reactome.org/PathwayBrowser/#/R-DRE-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Danio rerio 57705 R-DRE-2025724 https://reactome.org/PathwayBrowser/#/R-DRE-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Danio rerio 57705 R-DRE-4085021 https://reactome.org/PathwayBrowser/#/R-DRE-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Danio rerio 57705 R-DRE-446191 https://reactome.org/PathwayBrowser/#/R-DRE-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Danio rerio 57705 R-DRE-446204 https://reactome.org/PathwayBrowser/#/R-DRE-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Danio rerio 57705 R-DRE-5617037 https://reactome.org/PathwayBrowser/#/R-DRE-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Danio rerio 57705 R-DRE-741450 https://reactome.org/PathwayBrowser/#/R-DRE-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Danio rerio 57705 R-DRE-742354 https://reactome.org/PathwayBrowser/#/R-DRE-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Danio rerio 57705 R-DRE-8879117 https://reactome.org/PathwayBrowser/#/R-DRE-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Danio rerio 57705 R-DRE-914005 https://reactome.org/PathwayBrowser/#/R-DRE-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Danio rerio 57705 R-DRE-914008 https://reactome.org/PathwayBrowser/#/R-DRE-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Danio rerio 57705 R-DRE-914010 https://reactome.org/PathwayBrowser/#/R-DRE-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Danio rerio 57705 R-DRE-914012 https://reactome.org/PathwayBrowser/#/R-DRE-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Danio rerio 57705 R-DRE-964768 https://reactome.org/PathwayBrowser/#/R-DRE-964768 Addition of GlcNAc to the glycan on the A arm IEA Danio rerio 57705 R-DRE-975829 https://reactome.org/PathwayBrowser/#/R-DRE-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Danio rerio 57705 R-DRE-975903 https://reactome.org/PathwayBrowser/#/R-DRE-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Danio rerio 57705 R-DRE-975916 https://reactome.org/PathwayBrowser/#/R-DRE-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Danio rerio 57705 R-DRE-9846501 https://reactome.org/PathwayBrowser/#/R-DRE-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Danio rerio 57705 R-GGA-162730 https://reactome.org/PathwayBrowser/#/R-GGA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Gallus gallus 57705 R-GGA-174368 https://reactome.org/PathwayBrowser/#/R-GGA-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Gallus gallus 57705 R-GGA-2025724 https://reactome.org/PathwayBrowser/#/R-GGA-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Gallus gallus 57705 R-GGA-4085021 https://reactome.org/PathwayBrowser/#/R-GGA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Gallus gallus 57705 R-GGA-446191 https://reactome.org/PathwayBrowser/#/R-GGA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Gallus gallus 57705 R-GGA-446204 https://reactome.org/PathwayBrowser/#/R-GGA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Gallus gallus 57705 R-GGA-446207 https://reactome.org/PathwayBrowser/#/R-GGA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Gallus gallus 57705 R-GGA-5617037 https://reactome.org/PathwayBrowser/#/R-GGA-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Gallus gallus 57705 R-GGA-5694487 https://reactome.org/PathwayBrowser/#/R-GGA-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Gallus gallus 57705 R-GGA-741450 https://reactome.org/PathwayBrowser/#/R-GGA-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Gallus gallus 57705 R-GGA-742354 https://reactome.org/PathwayBrowser/#/R-GGA-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Gallus gallus 57705 R-GGA-744231 https://reactome.org/PathwayBrowser/#/R-GGA-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Gallus gallus 57705 R-GGA-8879117 https://reactome.org/PathwayBrowser/#/R-GGA-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Gallus gallus 57705 R-GGA-914005 https://reactome.org/PathwayBrowser/#/R-GGA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Gallus gallus 57705 R-GGA-914008 https://reactome.org/PathwayBrowser/#/R-GGA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Gallus gallus 57705 R-GGA-914010 https://reactome.org/PathwayBrowser/#/R-GGA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Gallus gallus 57705 R-GGA-914012 https://reactome.org/PathwayBrowser/#/R-GGA-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Gallus gallus 57705 R-GGA-914018 https://reactome.org/PathwayBrowser/#/R-GGA-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Gallus gallus 57705 R-GGA-964768 https://reactome.org/PathwayBrowser/#/R-GGA-964768 Addition of GlcNAc to the glycan on the A arm IEA Gallus gallus 57705 R-GGA-975829 https://reactome.org/PathwayBrowser/#/R-GGA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Gallus gallus 57705 R-GGA-975903 https://reactome.org/PathwayBrowser/#/R-GGA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Gallus gallus 57705 R-GGA-975916 https://reactome.org/PathwayBrowser/#/R-GGA-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Gallus gallus 57705 R-GGA-975926 https://reactome.org/PathwayBrowser/#/R-GGA-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Gallus gallus 57705 R-GGA-9846501 https://reactome.org/PathwayBrowser/#/R-GGA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Gallus gallus 57705 R-HSA-162730 https://reactome.org/PathwayBrowser/#/R-HSA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP TAS Homo sapiens 57705 R-HSA-174368 https://reactome.org/PathwayBrowser/#/R-HSA-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen TAS Homo sapiens 57705 R-HSA-1912355 https://reactome.org/PathwayBrowser/#/R-HSA-1912355 Glycosylation of Pre-NOTCH by FRINGE IEA Homo sapiens 57705 R-HSA-2022851 https://reactome.org/PathwayBrowser/#/R-HSA-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain TAS Homo sapiens 57705 R-HSA-2022919 https://reactome.org/PathwayBrowser/#/R-HSA-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue TAS Homo sapiens 57705 R-HSA-2025724 https://reactome.org/PathwayBrowser/#/R-HSA-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG TAS Homo sapiens 57705 R-HSA-3656254 https://reactome.org/PathwayBrowser/#/R-HSA-3656254 Defective EXT2 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain TAS Homo sapiens 57705 R-HSA-3656261 https://reactome.org/PathwayBrowser/#/R-HSA-3656261 Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain TAS Homo sapiens 57705 R-HSA-4085021 https://reactome.org/PathwayBrowser/#/R-HSA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP TAS Homo sapiens 57705 R-HSA-4088338 https://reactome.org/PathwayBrowser/#/R-HSA-4088338 Defective GNE does not hydrolyse UDP-GlcNAc TAS Homo sapiens 57705 R-HSA-446191 https://reactome.org/PathwayBrowser/#/R-HSA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate TAS Homo sapiens 57705 R-HSA-446204 https://reactome.org/PathwayBrowser/#/R-HSA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine TAS Homo sapiens 57705 R-HSA-446207 https://reactome.org/PathwayBrowser/#/R-HSA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP TAS Homo sapiens 57705 R-HSA-4549334 https://reactome.org/PathwayBrowser/#/R-HSA-4549334 Defective DPAGT1 does not transfer GlcNAc to DOLP TAS Homo sapiens 57705 R-HSA-4793955 https://reactome.org/PathwayBrowser/#/R-HSA-4793955 Defective MGAT2 does not transfer GlcNAc to N-glycans TAS Homo sapiens 57705 R-HSA-5096538 https://reactome.org/PathwayBrowser/#/R-HSA-5096538 Defective LFNG does not transfer GlcNAc to Pre-NOTCH TAS Homo sapiens 57705 R-HSA-5603297 https://reactome.org/PathwayBrowser/#/R-HSA-5603297 Defective SLC35D1 does not transport UDP-GlcA, UDPGlcNAc TAS Homo sapiens 57705 R-HSA-5617037 https://reactome.org/PathwayBrowser/#/R-HSA-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 TAS Homo sapiens 57705 R-HSA-5617096 https://reactome.org/PathwayBrowser/#/R-HSA-5617096 Defective POMGNT1 does not transfer GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 TAS Homo sapiens 57705 R-HSA-5633241 https://reactome.org/PathwayBrowser/#/R-HSA-5633241 Defective ALG14 does not transfer GlcNAc from UDP-GlcNAc to GlcNAcDOLP TAS Homo sapiens 57705 R-HSA-5653622 https://reactome.org/PathwayBrowser/#/R-HSA-5653622 Defective SLC35A3 does not exchange UDP-GlcNAc for UMP TAS Homo sapiens 57705 R-HSA-5694487 https://reactome.org/PathwayBrowser/#/R-HSA-5694487 A4GNT transfers GlcNAc to core 2 mucins TAS Homo sapiens 57705 R-HSA-741450 https://reactome.org/PathwayBrowser/#/R-HSA-741450 SLC35A3 exchanges UDP-GlcNAc for UMP TAS Homo sapiens 57705 R-HSA-742354 https://reactome.org/PathwayBrowser/#/R-HSA-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen TAS Homo sapiens 57705 R-HSA-744231 https://reactome.org/PathwayBrowser/#/R-HSA-744231 SLC35D2 exchanges UDP-GlcNAc for UMP TAS Homo sapiens 57705 R-HSA-8879117 https://reactome.org/PathwayBrowser/#/R-HSA-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 TAS Homo sapiens 57705 R-HSA-9036283 https://reactome.org/PathwayBrowser/#/R-HSA-9036283 Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the terminal GlcA residue TAS Homo sapiens 57705 R-HSA-9036290 https://reactome.org/PathwayBrowser/#/R-HSA-9036290 Defective EXT2 (in EXT1:EXT2) does not transfer GlcNAc to heparan TAS Homo sapiens 57705 R-HSA-914005 https://reactome.org/PathwayBrowser/#/R-HSA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein TAS Homo sapiens 57705 R-HSA-914008 https://reactome.org/PathwayBrowser/#/R-HSA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein TAS Homo sapiens 57705 R-HSA-914010 https://reactome.org/PathwayBrowser/#/R-HSA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein TAS Homo sapiens 57705 R-HSA-914012 https://reactome.org/PathwayBrowser/#/R-HSA-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins TAS Homo sapiens 57705 R-HSA-914018 https://reactome.org/PathwayBrowser/#/R-HSA-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein TAS Homo sapiens 57705 R-HSA-964768 https://reactome.org/PathwayBrowser/#/R-HSA-964768 Addition of GlcNAc to the glycan on the A arm TAS Homo sapiens 57705 R-HSA-9683648 https://reactome.org/PathwayBrowser/#/R-HSA-9683648 Spike trimer glycoside chains are extended TAS Homo sapiens 57705 R-HSA-9687828 https://reactome.org/PathwayBrowser/#/R-HSA-9687828 O-GlcNAcylation of RIPK3 (TLR4 signaling) TAS Homo sapiens 57705 R-HSA-975829 https://reactome.org/PathwayBrowser/#/R-HSA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 TAS Homo sapiens 57705 R-HSA-975903 https://reactome.org/PathwayBrowser/#/R-HSA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV TAS Homo sapiens 57705 R-HSA-975916 https://reactome.org/PathwayBrowser/#/R-HSA-975916 Addition of GlcNAc to position 5 by MGAT5 TAS Homo sapiens 57705 R-HSA-975926 https://reactome.org/PathwayBrowser/#/R-HSA-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 TAS Homo sapiens 57705 R-HSA-9846501 https://reactome.org/PathwayBrowser/#/R-HSA-9846501 B3GNT5 transfers GlcNAc to LacCer TAS Homo sapiens 57705 R-MMU-162730 https://reactome.org/PathwayBrowser/#/R-MMU-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Mus musculus 57705 R-MMU-174368 https://reactome.org/PathwayBrowser/#/R-MMU-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Mus musculus 57705 R-MMU-2022851 https://reactome.org/PathwayBrowser/#/R-MMU-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Mus musculus 57705 R-MMU-2022919 https://reactome.org/PathwayBrowser/#/R-MMU-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Mus musculus 57705 R-MMU-2023158 https://reactome.org/PathwayBrowser/#/R-MMU-2023158 Glycosylation of Pre-Notch by Fringe TAS Mus musculus 57705 R-MMU-2025724 https://reactome.org/PathwayBrowser/#/R-MMU-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Mus musculus 57705 R-MMU-4085021 https://reactome.org/PathwayBrowser/#/R-MMU-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Mus musculus 57705 R-MMU-446191 https://reactome.org/PathwayBrowser/#/R-MMU-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Mus musculus 57705 R-MMU-446204 https://reactome.org/PathwayBrowser/#/R-MMU-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Mus musculus 57705 R-MMU-446207 https://reactome.org/PathwayBrowser/#/R-MMU-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Mus musculus 57705 R-MMU-5617037 https://reactome.org/PathwayBrowser/#/R-MMU-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Mus musculus 57705 R-MMU-5694487 https://reactome.org/PathwayBrowser/#/R-MMU-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Mus musculus 57705 R-MMU-741450 https://reactome.org/PathwayBrowser/#/R-MMU-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Mus musculus 57705 R-MMU-742354 https://reactome.org/PathwayBrowser/#/R-MMU-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Mus musculus 57705 R-MMU-744231 https://reactome.org/PathwayBrowser/#/R-MMU-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Mus musculus 57705 R-MMU-8879117 https://reactome.org/PathwayBrowser/#/R-MMU-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Mus musculus 57705 R-MMU-914005 https://reactome.org/PathwayBrowser/#/R-MMU-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Mus musculus 57705 R-MMU-914008 https://reactome.org/PathwayBrowser/#/R-MMU-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Mus musculus 57705 R-MMU-914010 https://reactome.org/PathwayBrowser/#/R-MMU-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Mus musculus 57705 R-MMU-914012 https://reactome.org/PathwayBrowser/#/R-MMU-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Mus musculus 57705 R-MMU-914018 https://reactome.org/PathwayBrowser/#/R-MMU-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Mus musculus 57705 R-MMU-964768 https://reactome.org/PathwayBrowser/#/R-MMU-964768 Addition of GlcNAc to the glycan on the A arm IEA Mus musculus 57705 R-MMU-9687828 https://reactome.org/PathwayBrowser/#/R-MMU-9687828 O-GlcNAcylation of RIPK3 (TLR4 signaling) IEA Mus musculus 57705 R-MMU-975829 https://reactome.org/PathwayBrowser/#/R-MMU-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Mus musculus 57705 R-MMU-975903 https://reactome.org/PathwayBrowser/#/R-MMU-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Mus musculus 57705 R-MMU-975916 https://reactome.org/PathwayBrowser/#/R-MMU-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Mus musculus 57705 R-MMU-975926 https://reactome.org/PathwayBrowser/#/R-MMU-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Mus musculus 57705 R-MMU-9846501 https://reactome.org/PathwayBrowser/#/R-MMU-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Mus musculus 57705 R-MTU-879298 https://reactome.org/PathwayBrowser/#/R-MTU-879298 acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate TAS Mycobacterium tuberculosis 57705 R-PFA-446191 https://reactome.org/PathwayBrowser/#/R-PFA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Plasmodium falciparum 57705 R-PFA-446204 https://reactome.org/PathwayBrowser/#/R-PFA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Plasmodium falciparum 57705 R-PFA-446207 https://reactome.org/PathwayBrowser/#/R-PFA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Plasmodium falciparum 57705 R-PFA-914005 https://reactome.org/PathwayBrowser/#/R-PFA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Plasmodium falciparum 57705 R-PFA-914008 https://reactome.org/PathwayBrowser/#/R-PFA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Plasmodium falciparum 57705 R-RNO-162730 https://reactome.org/PathwayBrowser/#/R-RNO-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Rattus norvegicus 57705 R-RNO-174368 https://reactome.org/PathwayBrowser/#/R-RNO-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Rattus norvegicus 57705 R-RNO-2022851 https://reactome.org/PathwayBrowser/#/R-RNO-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Rattus norvegicus 57705 R-RNO-2022919 https://reactome.org/PathwayBrowser/#/R-RNO-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Rattus norvegicus 57705 R-RNO-2025724 https://reactome.org/PathwayBrowser/#/R-RNO-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Rattus norvegicus 57705 R-RNO-4085021 https://reactome.org/PathwayBrowser/#/R-RNO-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Rattus norvegicus 57705 R-RNO-446191 https://reactome.org/PathwayBrowser/#/R-RNO-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Rattus norvegicus 57705 R-RNO-446204 https://reactome.org/PathwayBrowser/#/R-RNO-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Rattus norvegicus 57705 R-RNO-446207 https://reactome.org/PathwayBrowser/#/R-RNO-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Rattus norvegicus 57705 R-RNO-5617037 https://reactome.org/PathwayBrowser/#/R-RNO-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Rattus norvegicus 57705 R-RNO-5694487 https://reactome.org/PathwayBrowser/#/R-RNO-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Rattus norvegicus 57705 R-RNO-741450 https://reactome.org/PathwayBrowser/#/R-RNO-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Rattus norvegicus 57705 R-RNO-742354 https://reactome.org/PathwayBrowser/#/R-RNO-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Rattus norvegicus 57705 R-RNO-744231 https://reactome.org/PathwayBrowser/#/R-RNO-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Rattus norvegicus 57705 R-RNO-8879117 https://reactome.org/PathwayBrowser/#/R-RNO-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Rattus norvegicus 57705 R-RNO-914005 https://reactome.org/PathwayBrowser/#/R-RNO-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Rattus norvegicus 57705 R-RNO-914008 https://reactome.org/PathwayBrowser/#/R-RNO-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Rattus norvegicus 57705 R-RNO-914010 https://reactome.org/PathwayBrowser/#/R-RNO-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Rattus norvegicus 57705 R-RNO-914012 https://reactome.org/PathwayBrowser/#/R-RNO-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Rattus norvegicus 57705 R-RNO-914018 https://reactome.org/PathwayBrowser/#/R-RNO-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Rattus norvegicus 57705 R-RNO-964768 https://reactome.org/PathwayBrowser/#/R-RNO-964768 Addition of GlcNAc to the glycan on the A arm IEA Rattus norvegicus 57705 R-RNO-9687828 https://reactome.org/PathwayBrowser/#/R-RNO-9687828 O-GlcNAcylation of RIPK3 (TLR4 signaling) IEA Rattus norvegicus 57705 R-RNO-975829 https://reactome.org/PathwayBrowser/#/R-RNO-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Rattus norvegicus 57705 R-RNO-975903 https://reactome.org/PathwayBrowser/#/R-RNO-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Rattus norvegicus 57705 R-RNO-975916 https://reactome.org/PathwayBrowser/#/R-RNO-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Rattus norvegicus 57705 R-RNO-975926 https://reactome.org/PathwayBrowser/#/R-RNO-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Rattus norvegicus 57705 R-RNO-9846501 https://reactome.org/PathwayBrowser/#/R-RNO-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Rattus norvegicus 57705 R-SCE-446191 https://reactome.org/PathwayBrowser/#/R-SCE-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Saccharomyces cerevisiae 57705 R-SCE-446204 https://reactome.org/PathwayBrowser/#/R-SCE-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Saccharomyces cerevisiae 57705 R-SCE-742354 https://reactome.org/PathwayBrowser/#/R-SCE-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Saccharomyces cerevisiae 57705 R-SPO-446191 https://reactome.org/PathwayBrowser/#/R-SPO-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Schizosaccharomyces pombe 57705 R-SPO-446204 https://reactome.org/PathwayBrowser/#/R-SPO-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Schizosaccharomyces pombe 57705 R-SPO-446207 https://reactome.org/PathwayBrowser/#/R-SPO-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Schizosaccharomyces pombe 57705 R-SPO-741450 https://reactome.org/PathwayBrowser/#/R-SPO-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Schizosaccharomyces pombe 57705 R-SPO-742354 https://reactome.org/PathwayBrowser/#/R-SPO-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Schizosaccharomyces pombe 57705 R-SSC-162730 https://reactome.org/PathwayBrowser/#/R-SSC-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Sus scrofa 57705 R-SSC-174368 https://reactome.org/PathwayBrowser/#/R-SSC-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Sus scrofa 57705 R-SSC-2022851 https://reactome.org/PathwayBrowser/#/R-SSC-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Sus scrofa 57705 R-SSC-2022919 https://reactome.org/PathwayBrowser/#/R-SSC-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Sus scrofa 57705 R-SSC-2025724 https://reactome.org/PathwayBrowser/#/R-SSC-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Sus scrofa 57705 R-SSC-4085021 https://reactome.org/PathwayBrowser/#/R-SSC-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Sus scrofa 57705 R-SSC-446191 https://reactome.org/PathwayBrowser/#/R-SSC-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Sus scrofa 57705 R-SSC-446204 https://reactome.org/PathwayBrowser/#/R-SSC-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Sus scrofa 57705 R-SSC-446207 https://reactome.org/PathwayBrowser/#/R-SSC-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Sus scrofa 57705 R-SSC-5617037 https://reactome.org/PathwayBrowser/#/R-SSC-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Sus scrofa 57705 R-SSC-5694487 https://reactome.org/PathwayBrowser/#/R-SSC-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Sus scrofa 57705 R-SSC-741450 https://reactome.org/PathwayBrowser/#/R-SSC-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Sus scrofa 57705 R-SSC-742354 https://reactome.org/PathwayBrowser/#/R-SSC-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Sus scrofa 57705 R-SSC-744231 https://reactome.org/PathwayBrowser/#/R-SSC-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Sus scrofa 57705 R-SSC-8879117 https://reactome.org/PathwayBrowser/#/R-SSC-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Sus scrofa 57705 R-SSC-914005 https://reactome.org/PathwayBrowser/#/R-SSC-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Sus scrofa 57705 R-SSC-914008 https://reactome.org/PathwayBrowser/#/R-SSC-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Sus scrofa 57705 R-SSC-914010 https://reactome.org/PathwayBrowser/#/R-SSC-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Sus scrofa 57705 R-SSC-914012 https://reactome.org/PathwayBrowser/#/R-SSC-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Sus scrofa 57705 R-SSC-914018 https://reactome.org/PathwayBrowser/#/R-SSC-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Sus scrofa 57705 R-SSC-964768 https://reactome.org/PathwayBrowser/#/R-SSC-964768 Addition of GlcNAc to the glycan on the A arm IEA Sus scrofa 57705 R-SSC-975829 https://reactome.org/PathwayBrowser/#/R-SSC-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Sus scrofa 57705 R-SSC-975903 https://reactome.org/PathwayBrowser/#/R-SSC-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Sus scrofa 57705 R-SSC-975916 https://reactome.org/PathwayBrowser/#/R-SSC-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Sus scrofa 57705 R-SSC-975926 https://reactome.org/PathwayBrowser/#/R-SSC-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Sus scrofa 57705 R-SSC-9846501 https://reactome.org/PathwayBrowser/#/R-SSC-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Sus scrofa 57705 R-XTR-162730 https://reactome.org/PathwayBrowser/#/R-XTR-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Xenopus tropicalis 57705 R-XTR-2025724 https://reactome.org/PathwayBrowser/#/R-XTR-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Xenopus tropicalis 57705 R-XTR-4085021 https://reactome.org/PathwayBrowser/#/R-XTR-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Xenopus tropicalis 57705 R-XTR-446191 https://reactome.org/PathwayBrowser/#/R-XTR-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Xenopus tropicalis 57705 R-XTR-446204 https://reactome.org/PathwayBrowser/#/R-XTR-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Xenopus tropicalis 57705 R-XTR-446207 https://reactome.org/PathwayBrowser/#/R-XTR-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Xenopus tropicalis 57705 R-XTR-5617037 https://reactome.org/PathwayBrowser/#/R-XTR-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Xenopus tropicalis 57705 R-XTR-5694487 https://reactome.org/PathwayBrowser/#/R-XTR-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Xenopus tropicalis 57705 R-XTR-741450 https://reactome.org/PathwayBrowser/#/R-XTR-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Xenopus tropicalis 57705 R-XTR-742354 https://reactome.org/PathwayBrowser/#/R-XTR-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Xenopus tropicalis 57705 R-XTR-744231 https://reactome.org/PathwayBrowser/#/R-XTR-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Xenopus tropicalis 57705 R-XTR-8879117 https://reactome.org/PathwayBrowser/#/R-XTR-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Xenopus tropicalis 57705 R-XTR-914005 https://reactome.org/PathwayBrowser/#/R-XTR-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Xenopus tropicalis 57705 R-XTR-914008 https://reactome.org/PathwayBrowser/#/R-XTR-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Xenopus tropicalis 57705 R-XTR-914010 https://reactome.org/PathwayBrowser/#/R-XTR-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Xenopus tropicalis 57705 R-XTR-914012 https://reactome.org/PathwayBrowser/#/R-XTR-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Xenopus tropicalis 57705 R-XTR-914018 https://reactome.org/PathwayBrowser/#/R-XTR-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Xenopus tropicalis 57705 R-XTR-964768 https://reactome.org/PathwayBrowser/#/R-XTR-964768 Addition of GlcNAc to the glycan on the A arm IEA Xenopus tropicalis 57705 R-XTR-975829 https://reactome.org/PathwayBrowser/#/R-XTR-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Xenopus tropicalis 57705 R-XTR-975903 https://reactome.org/PathwayBrowser/#/R-XTR-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Xenopus tropicalis 57705 R-XTR-975916 https://reactome.org/PathwayBrowser/#/R-XTR-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Xenopus tropicalis 57705 R-XTR-975926 https://reactome.org/PathwayBrowser/#/R-XTR-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Xenopus tropicalis 57705 R-XTR-9846501 https://reactome.org/PathwayBrowser/#/R-XTR-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Xenopus tropicalis 57706 R-BTA-880002 https://reactome.org/PathwayBrowser/#/R-BTA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Bos taurus 57706 R-BTA-880033 https://reactome.org/PathwayBrowser/#/R-BTA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Bos taurus 57706 R-BTA-888548 https://reactome.org/PathwayBrowser/#/R-BTA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Bos taurus 57706 R-BTA-916855 https://reactome.org/PathwayBrowser/#/R-BTA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Bos taurus 57706 R-CEL-880002 https://reactome.org/PathwayBrowser/#/R-CEL-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Caenorhabditis elegans 57706 R-CEL-880033 https://reactome.org/PathwayBrowser/#/R-CEL-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Caenorhabditis elegans 57706 R-CEL-888548 https://reactome.org/PathwayBrowser/#/R-CEL-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Caenorhabditis elegans 57706 R-CEL-916855 https://reactome.org/PathwayBrowser/#/R-CEL-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Caenorhabditis elegans 57706 R-CFA-880002 https://reactome.org/PathwayBrowser/#/R-CFA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Canis familiaris 57706 R-CFA-880033 https://reactome.org/PathwayBrowser/#/R-CFA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Canis familiaris 57706 R-CFA-888548 https://reactome.org/PathwayBrowser/#/R-CFA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Canis familiaris 57706 R-CFA-916855 https://reactome.org/PathwayBrowser/#/R-CFA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Canis familiaris 57706 R-DDI-880002 https://reactome.org/PathwayBrowser/#/R-DDI-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Dictyostelium discoideum 57706 R-DDI-880033 https://reactome.org/PathwayBrowser/#/R-DDI-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Dictyostelium discoideum 57706 R-DDI-916855 https://reactome.org/PathwayBrowser/#/R-DDI-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Dictyostelium discoideum 57706 R-DME-880002 https://reactome.org/PathwayBrowser/#/R-DME-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Drosophila melanogaster 57706 R-DME-880033 https://reactome.org/PathwayBrowser/#/R-DME-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Drosophila melanogaster 57706 R-DME-888548 https://reactome.org/PathwayBrowser/#/R-DME-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Drosophila melanogaster 57706 R-DME-916855 https://reactome.org/PathwayBrowser/#/R-DME-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Drosophila melanogaster 57706 R-DRE-880002 https://reactome.org/PathwayBrowser/#/R-DRE-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Danio rerio 57706 R-DRE-880033 https://reactome.org/PathwayBrowser/#/R-DRE-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Danio rerio 57706 R-DRE-916855 https://reactome.org/PathwayBrowser/#/R-DRE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Danio rerio 57706 R-GGA-880002 https://reactome.org/PathwayBrowser/#/R-GGA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Gallus gallus 57706 R-GGA-880033 https://reactome.org/PathwayBrowser/#/R-GGA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Gallus gallus 57706 R-GGA-888548 https://reactome.org/PathwayBrowser/#/R-GGA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Gallus gallus 57706 R-GGA-916855 https://reactome.org/PathwayBrowser/#/R-GGA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Gallus gallus 57706 R-HSA-880002 https://reactome.org/PathwayBrowser/#/R-HSA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate TAS Homo sapiens 57706 R-HSA-880033 https://reactome.org/PathwayBrowser/#/R-HSA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde TAS Homo sapiens 57706 R-HSA-888548 https://reactome.org/PathwayBrowser/#/R-HSA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA TAS Homo sapiens 57706 R-HSA-916855 https://reactome.org/PathwayBrowser/#/R-HSA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA TAS Homo sapiens 57706 R-MMU-880002 https://reactome.org/PathwayBrowser/#/R-MMU-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Mus musculus 57706 R-MMU-880033 https://reactome.org/PathwayBrowser/#/R-MMU-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Mus musculus 57706 R-MMU-888548 https://reactome.org/PathwayBrowser/#/R-MMU-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Mus musculus 57706 R-MMU-916855 https://reactome.org/PathwayBrowser/#/R-MMU-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Mus musculus 57706 R-RNO-880002 https://reactome.org/PathwayBrowser/#/R-RNO-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Rattus norvegicus 57706 R-RNO-880033 https://reactome.org/PathwayBrowser/#/R-RNO-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Rattus norvegicus 57706 R-RNO-888548 https://reactome.org/PathwayBrowser/#/R-RNO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Rattus norvegicus 57706 R-RNO-916855 https://reactome.org/PathwayBrowser/#/R-RNO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Rattus norvegicus 57706 R-SCE-888548 https://reactome.org/PathwayBrowser/#/R-SCE-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Saccharomyces cerevisiae 57706 R-SCE-916855 https://reactome.org/PathwayBrowser/#/R-SCE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Saccharomyces cerevisiae 57706 R-SPO-888548 https://reactome.org/PathwayBrowser/#/R-SPO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Schizosaccharomyces pombe 57706 R-SPO-916855 https://reactome.org/PathwayBrowser/#/R-SPO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Schizosaccharomyces pombe 57706 R-SSC-880002 https://reactome.org/PathwayBrowser/#/R-SSC-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Sus scrofa 57706 R-SSC-880033 https://reactome.org/PathwayBrowser/#/R-SSC-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Sus scrofa 57706 R-SSC-888548 https://reactome.org/PathwayBrowser/#/R-SSC-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Sus scrofa 57706 R-SSC-916855 https://reactome.org/PathwayBrowser/#/R-SSC-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Sus scrofa 57706 R-XTR-880002 https://reactome.org/PathwayBrowser/#/R-XTR-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Xenopus tropicalis 57706 R-XTR-880033 https://reactome.org/PathwayBrowser/#/R-XTR-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Xenopus tropicalis 57706 R-XTR-888548 https://reactome.org/PathwayBrowser/#/R-XTR-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Xenopus tropicalis 57706 R-XTR-916855 https://reactome.org/PathwayBrowser/#/R-XTR-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Xenopus tropicalis 57720 R-BTA-112033 https://reactome.org/PathwayBrowser/#/R-BTA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Bos taurus 57720 R-BTA-112034 https://reactome.org/PathwayBrowser/#/R-BTA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Bos taurus 57720 R-BTA-6787329 https://reactome.org/PathwayBrowser/#/R-BTA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Bos taurus 57720 R-BTA-74242 https://reactome.org/PathwayBrowser/#/R-BTA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Bos taurus 57720 R-BTA-74249 https://reactome.org/PathwayBrowser/#/R-BTA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Bos taurus 57720 R-BTA-74372 https://reactome.org/PathwayBrowser/#/R-BTA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Bos taurus 57720 R-BTA-74376 https://reactome.org/PathwayBrowser/#/R-BTA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Bos taurus 57720 R-BTA-9755044 https://reactome.org/PathwayBrowser/#/R-BTA-9755044 PNP trimer transforms RBV to T-CONH2 IEA Bos taurus 57720 R-CEL-112033 https://reactome.org/PathwayBrowser/#/R-CEL-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Caenorhabditis elegans 57720 R-CEL-112034 https://reactome.org/PathwayBrowser/#/R-CEL-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Caenorhabditis elegans 57720 R-CEL-6787329 https://reactome.org/PathwayBrowser/#/R-CEL-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Caenorhabditis elegans 57720 R-CEL-74242 https://reactome.org/PathwayBrowser/#/R-CEL-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Caenorhabditis elegans 57720 R-CEL-74249 https://reactome.org/PathwayBrowser/#/R-CEL-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Caenorhabditis elegans 57720 R-CEL-74372 https://reactome.org/PathwayBrowser/#/R-CEL-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Caenorhabditis elegans 57720 R-CEL-74376 https://reactome.org/PathwayBrowser/#/R-CEL-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Caenorhabditis elegans 57720 R-CEL-9755044 https://reactome.org/PathwayBrowser/#/R-CEL-9755044 PNP trimer transforms RBV to T-CONH2 IEA Caenorhabditis elegans 57720 R-CFA-112033 https://reactome.org/PathwayBrowser/#/R-CFA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Canis familiaris 57720 R-CFA-112034 https://reactome.org/PathwayBrowser/#/R-CFA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Canis familiaris 57720 R-CFA-6787329 https://reactome.org/PathwayBrowser/#/R-CFA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Canis familiaris 57720 R-CFA-74242 https://reactome.org/PathwayBrowser/#/R-CFA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Canis familiaris 57720 R-CFA-74249 https://reactome.org/PathwayBrowser/#/R-CFA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Canis familiaris 57720 R-CFA-74372 https://reactome.org/PathwayBrowser/#/R-CFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Canis familiaris 57720 R-CFA-74376 https://reactome.org/PathwayBrowser/#/R-CFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Canis familiaris 57720 R-CFA-9755044 https://reactome.org/PathwayBrowser/#/R-CFA-9755044 PNP trimer transforms RBV to T-CONH2 IEA Canis familiaris 57720 R-DDI-6787329 https://reactome.org/PathwayBrowser/#/R-DDI-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Dictyostelium discoideum 57720 R-DDI-74372 https://reactome.org/PathwayBrowser/#/R-DDI-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Dictyostelium discoideum 57720 R-DDI-74376 https://reactome.org/PathwayBrowser/#/R-DDI-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Dictyostelium discoideum 57720 R-DME-112033 https://reactome.org/PathwayBrowser/#/R-DME-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Drosophila melanogaster 57720 R-DME-112034 https://reactome.org/PathwayBrowser/#/R-DME-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Drosophila melanogaster 57720 R-DME-6787329 https://reactome.org/PathwayBrowser/#/R-DME-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Drosophila melanogaster 57720 R-DME-74242 https://reactome.org/PathwayBrowser/#/R-DME-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Drosophila melanogaster 57720 R-DME-74249 https://reactome.org/PathwayBrowser/#/R-DME-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Drosophila melanogaster 57720 R-DME-74372 https://reactome.org/PathwayBrowser/#/R-DME-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Drosophila melanogaster 57720 R-DME-74376 https://reactome.org/PathwayBrowser/#/R-DME-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Drosophila melanogaster 57720 R-DME-9755044 https://reactome.org/PathwayBrowser/#/R-DME-9755044 PNP trimer transforms RBV to T-CONH2 IEA Drosophila melanogaster 57720 R-DRE-112033 https://reactome.org/PathwayBrowser/#/R-DRE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Danio rerio 57720 R-DRE-112034 https://reactome.org/PathwayBrowser/#/R-DRE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Danio rerio 57720 R-DRE-6787329 https://reactome.org/PathwayBrowser/#/R-DRE-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Danio rerio 57720 R-DRE-74242 https://reactome.org/PathwayBrowser/#/R-DRE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Danio rerio 57720 R-DRE-74249 https://reactome.org/PathwayBrowser/#/R-DRE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Danio rerio 57720 R-DRE-74372 https://reactome.org/PathwayBrowser/#/R-DRE-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Danio rerio 57720 R-DRE-74376 https://reactome.org/PathwayBrowser/#/R-DRE-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Danio rerio 57720 R-DRE-9755044 https://reactome.org/PathwayBrowser/#/R-DRE-9755044 PNP trimer transforms RBV to T-CONH2 IEA Danio rerio 57720 R-GGA-421174 https://reactome.org/PathwayBrowser/#/R-GGA-421174 inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate IEA Gallus gallus 57720 R-GGA-6787329 https://reactome.org/PathwayBrowser/#/R-GGA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Gallus gallus 57720 R-GGA-74372 https://reactome.org/PathwayBrowser/#/R-GGA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Gallus gallus 57720 R-GGA-74376 https://reactome.org/PathwayBrowser/#/R-GGA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Gallus gallus 57720 R-HSA-112033 https://reactome.org/PathwayBrowser/#/R-HSA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine TAS Homo sapiens 57720 R-HSA-112034 https://reactome.org/PathwayBrowser/#/R-HSA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine TAS Homo sapiens 57720 R-HSA-6787329 https://reactome.org/PathwayBrowser/#/R-HSA-6787329 PGM2:Mg2+ isomerises R1P to R5P TAS Homo sapiens 57720 R-HSA-74242 https://reactome.org/PathwayBrowser/#/R-HSA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 57720 R-HSA-74249 https://reactome.org/PathwayBrowser/#/R-HSA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 57720 R-HSA-74372 https://reactome.org/PathwayBrowser/#/R-HSA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] TAS Homo sapiens 57720 R-HSA-74376 https://reactome.org/PathwayBrowser/#/R-HSA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) TAS Homo sapiens 57720 R-HSA-9755044 https://reactome.org/PathwayBrowser/#/R-HSA-9755044 PNP trimer transforms RBV to T-CONH2 TAS Homo sapiens 57720 R-MMU-112033 https://reactome.org/PathwayBrowser/#/R-MMU-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Mus musculus 57720 R-MMU-112034 https://reactome.org/PathwayBrowser/#/R-MMU-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Mus musculus 57720 R-MMU-6787329 https://reactome.org/PathwayBrowser/#/R-MMU-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Mus musculus 57720 R-MMU-74242 https://reactome.org/PathwayBrowser/#/R-MMU-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Mus musculus 57720 R-MMU-74249 https://reactome.org/PathwayBrowser/#/R-MMU-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Mus musculus 57720 R-MMU-74372 https://reactome.org/PathwayBrowser/#/R-MMU-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Mus musculus 57720 R-MMU-74376 https://reactome.org/PathwayBrowser/#/R-MMU-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Mus musculus 57720 R-MMU-9755044 https://reactome.org/PathwayBrowser/#/R-MMU-9755044 PNP trimer transforms RBV to T-CONH2 IEA Mus musculus 57720 R-PFA-6787329 https://reactome.org/PathwayBrowser/#/R-PFA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Plasmodium falciparum 57720 R-PFA-74372 https://reactome.org/PathwayBrowser/#/R-PFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Plasmodium falciparum 57720 R-PFA-74376 https://reactome.org/PathwayBrowser/#/R-PFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Plasmodium falciparum 57720 R-RNO-112033 https://reactome.org/PathwayBrowser/#/R-RNO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Rattus norvegicus 57720 R-RNO-112034 https://reactome.org/PathwayBrowser/#/R-RNO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Rattus norvegicus 57720 R-RNO-6787329 https://reactome.org/PathwayBrowser/#/R-RNO-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Rattus norvegicus 57720 R-RNO-74242 https://reactome.org/PathwayBrowser/#/R-RNO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Rattus norvegicus 57720 R-RNO-74249 https://reactome.org/PathwayBrowser/#/R-RNO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Rattus norvegicus 57720 R-RNO-74372 https://reactome.org/PathwayBrowser/#/R-RNO-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Rattus norvegicus 57720 R-RNO-74376 https://reactome.org/PathwayBrowser/#/R-RNO-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Rattus norvegicus 57720 R-RNO-9755044 https://reactome.org/PathwayBrowser/#/R-RNO-9755044 PNP trimer transforms RBV to T-CONH2 IEA Rattus norvegicus 57720 R-SCE-112033 https://reactome.org/PathwayBrowser/#/R-SCE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Saccharomyces cerevisiae 57720 R-SCE-112034 https://reactome.org/PathwayBrowser/#/R-SCE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Saccharomyces cerevisiae 57720 R-SCE-6787329 https://reactome.org/PathwayBrowser/#/R-SCE-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Saccharomyces cerevisiae 57720 R-SCE-74242 https://reactome.org/PathwayBrowser/#/R-SCE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Saccharomyces cerevisiae 57720 R-SCE-74249 https://reactome.org/PathwayBrowser/#/R-SCE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Saccharomyces cerevisiae 57720 R-SCE-9755044 https://reactome.org/PathwayBrowser/#/R-SCE-9755044 PNP trimer transforms RBV to T-CONH2 IEA Saccharomyces cerevisiae 57720 R-SPO-112033 https://reactome.org/PathwayBrowser/#/R-SPO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Schizosaccharomyces pombe 57720 R-SPO-112034 https://reactome.org/PathwayBrowser/#/R-SPO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Schizosaccharomyces pombe 57720 R-SPO-6787329 https://reactome.org/PathwayBrowser/#/R-SPO-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Schizosaccharomyces pombe 57720 R-SPO-74242 https://reactome.org/PathwayBrowser/#/R-SPO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Schizosaccharomyces pombe 57720 R-SPO-74249 https://reactome.org/PathwayBrowser/#/R-SPO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Schizosaccharomyces pombe 57720 R-SPO-9755044 https://reactome.org/PathwayBrowser/#/R-SPO-9755044 PNP trimer transforms RBV to T-CONH2 IEA Schizosaccharomyces pombe 57720 R-SSC-112033 https://reactome.org/PathwayBrowser/#/R-SSC-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Sus scrofa 57720 R-SSC-112034 https://reactome.org/PathwayBrowser/#/R-SSC-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Sus scrofa 57720 R-SSC-6787329 https://reactome.org/PathwayBrowser/#/R-SSC-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Sus scrofa 57720 R-SSC-74242 https://reactome.org/PathwayBrowser/#/R-SSC-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Sus scrofa 57720 R-SSC-74249 https://reactome.org/PathwayBrowser/#/R-SSC-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Sus scrofa 57720 R-SSC-74372 https://reactome.org/PathwayBrowser/#/R-SSC-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Sus scrofa 57720 R-SSC-74376 https://reactome.org/PathwayBrowser/#/R-SSC-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Sus scrofa 57720 R-SSC-9755044 https://reactome.org/PathwayBrowser/#/R-SSC-9755044 PNP trimer transforms RBV to T-CONH2 IEA Sus scrofa 57720 R-XTR-112033 https://reactome.org/PathwayBrowser/#/R-XTR-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Xenopus tropicalis 57720 R-XTR-112034 https://reactome.org/PathwayBrowser/#/R-XTR-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Xenopus tropicalis 57720 R-XTR-6787329 https://reactome.org/PathwayBrowser/#/R-XTR-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Xenopus tropicalis 57720 R-XTR-74242 https://reactome.org/PathwayBrowser/#/R-XTR-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Xenopus tropicalis 57720 R-XTR-74249 https://reactome.org/PathwayBrowser/#/R-XTR-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Xenopus tropicalis 57720 R-XTR-74372 https://reactome.org/PathwayBrowser/#/R-XTR-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Xenopus tropicalis 57720 R-XTR-74376 https://reactome.org/PathwayBrowser/#/R-XTR-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Xenopus tropicalis 57720 R-XTR-9755044 https://reactome.org/PathwayBrowser/#/R-XTR-9755044 PNP trimer transforms RBV to T-CONH2 IEA Xenopus tropicalis 57731 R-BTA-73620 https://reactome.org/PathwayBrowser/#/R-BTA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Bos taurus 57731 R-CEL-73620 https://reactome.org/PathwayBrowser/#/R-CEL-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Caenorhabditis elegans 57731 R-CFA-73620 https://reactome.org/PathwayBrowser/#/R-CFA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Canis familiaris 57731 R-DDI-73620 https://reactome.org/PathwayBrowser/#/R-DDI-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Dictyostelium discoideum 57731 R-DME-73620 https://reactome.org/PathwayBrowser/#/R-DME-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Drosophila melanogaster 57731 R-DRE-73620 https://reactome.org/PathwayBrowser/#/R-DRE-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Danio rerio 57731 R-GGA-73620 https://reactome.org/PathwayBrowser/#/R-GGA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Gallus gallus 57731 R-HSA-73620 https://reactome.org/PathwayBrowser/#/R-HSA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 TAS Homo sapiens 57731 R-HSA-909755 https://reactome.org/PathwayBrowser/#/R-HSA-909755 Mitochondrial uptake of (R)-3-aminoisobutyric acid IEA Homo sapiens 57731 R-HSA-909780 https://reactome.org/PathwayBrowser/#/R-HSA-909780 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine IEA Homo sapiens 57731 R-MMU-73620 https://reactome.org/PathwayBrowser/#/R-MMU-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Mus musculus 57731 R-RNO-73620 https://reactome.org/PathwayBrowser/#/R-RNO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Rattus norvegicus 57731 R-RNO-909775 https://reactome.org/PathwayBrowser/#/R-RNO-909775 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine TAS Rattus norvegicus 57731 R-RNO-909781 https://reactome.org/PathwayBrowser/#/R-RNO-909781 Mitochondrial uptake of (R)-3-aminoisobutyric acid TAS Rattus norvegicus 57731 R-SPO-73620 https://reactome.org/PathwayBrowser/#/R-SPO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Schizosaccharomyces pombe 57731 R-SSC-73620 https://reactome.org/PathwayBrowser/#/R-SSC-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Sus scrofa 57733 R-BTA-1855162 https://reactome.org/PathwayBrowser/#/R-BTA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Bos taurus 57733 R-BTA-1855163 https://reactome.org/PathwayBrowser/#/R-BTA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Bos taurus 57733 R-BTA-1855166 https://reactome.org/PathwayBrowser/#/R-BTA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Bos taurus 57733 R-BTA-1855176 https://reactome.org/PathwayBrowser/#/R-BTA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Bos taurus 57733 R-BTA-1855179 https://reactome.org/PathwayBrowser/#/R-BTA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Bos taurus 57733 R-BTA-1855181 https://reactome.org/PathwayBrowser/#/R-BTA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Bos taurus 57733 R-BTA-1855185 https://reactome.org/PathwayBrowser/#/R-BTA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 57733 R-BTA-1855206 https://reactome.org/PathwayBrowser/#/R-BTA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 57733 R-BTA-1855219 https://reactome.org/PathwayBrowser/#/R-BTA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Bos taurus 57733 R-BTA-1855223 https://reactome.org/PathwayBrowser/#/R-BTA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Bos taurus 57733 R-BTA-1855228 https://reactome.org/PathwayBrowser/#/R-BTA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 57733 R-BTA-9687638 https://reactome.org/PathwayBrowser/#/R-BTA-9687638 MLKL binds IP4, IP5 and IP6 IEA Bos taurus 57733 R-BTA-994137 https://reactome.org/PathwayBrowser/#/R-BTA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Bos taurus 57733 R-CEL-1855166 https://reactome.org/PathwayBrowser/#/R-CEL-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Caenorhabditis elegans 57733 R-CEL-1855181 https://reactome.org/PathwayBrowser/#/R-CEL-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 57733 R-CEL-1855185 https://reactome.org/PathwayBrowser/#/R-CEL-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 57733 R-CEL-1855206 https://reactome.org/PathwayBrowser/#/R-CEL-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 57733 R-CEL-1855223 https://reactome.org/PathwayBrowser/#/R-CEL-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 57733 R-CEL-1855228 https://reactome.org/PathwayBrowser/#/R-CEL-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 57733 R-CFA-1855162 https://reactome.org/PathwayBrowser/#/R-CFA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Canis familiaris 57733 R-CFA-1855163 https://reactome.org/PathwayBrowser/#/R-CFA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Canis familiaris 57733 R-CFA-1855166 https://reactome.org/PathwayBrowser/#/R-CFA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Canis familiaris 57733 R-CFA-1855176 https://reactome.org/PathwayBrowser/#/R-CFA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Canis familiaris 57733 R-CFA-1855179 https://reactome.org/PathwayBrowser/#/R-CFA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Canis familiaris 57733 R-CFA-1855181 https://reactome.org/PathwayBrowser/#/R-CFA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Canis familiaris 57733 R-CFA-1855185 https://reactome.org/PathwayBrowser/#/R-CFA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 57733 R-CFA-1855206 https://reactome.org/PathwayBrowser/#/R-CFA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 57733 R-CFA-1855219 https://reactome.org/PathwayBrowser/#/R-CFA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 57733 R-CFA-1855223 https://reactome.org/PathwayBrowser/#/R-CFA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Canis familiaris 57733 R-CFA-1855228 https://reactome.org/PathwayBrowser/#/R-CFA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 57733 R-CFA-994137 https://reactome.org/PathwayBrowser/#/R-CFA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Canis familiaris 57733 R-DDI-1855162 https://reactome.org/PathwayBrowser/#/R-DDI-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Dictyostelium discoideum 57733 R-DDI-1855163 https://reactome.org/PathwayBrowser/#/R-DDI-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 57733 R-DDI-1855166 https://reactome.org/PathwayBrowser/#/R-DDI-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Dictyostelium discoideum 57733 R-DDI-1855181 https://reactome.org/PathwayBrowser/#/R-DDI-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 57733 R-DDI-1855185 https://reactome.org/PathwayBrowser/#/R-DDI-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 57733 R-DDI-1855206 https://reactome.org/PathwayBrowser/#/R-DDI-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 57733 R-DDI-1855219 https://reactome.org/PathwayBrowser/#/R-DDI-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 57733 R-DDI-1855223 https://reactome.org/PathwayBrowser/#/R-DDI-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 57733 R-DDI-1855228 https://reactome.org/PathwayBrowser/#/R-DDI-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 57733 R-DDI-994137 https://reactome.org/PathwayBrowser/#/R-DDI-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Dictyostelium discoideum 57733 R-DME-1855166 https://reactome.org/PathwayBrowser/#/R-DME-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Drosophila melanogaster 57733 R-DME-1855181 https://reactome.org/PathwayBrowser/#/R-DME-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 57733 R-DME-1855185 https://reactome.org/PathwayBrowser/#/R-DME-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 57733 R-DME-1855206 https://reactome.org/PathwayBrowser/#/R-DME-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 57733 R-DME-1855223 https://reactome.org/PathwayBrowser/#/R-DME-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 57733 R-DME-1855228 https://reactome.org/PathwayBrowser/#/R-DME-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 57733 R-DRE-1855162 https://reactome.org/PathwayBrowser/#/R-DRE-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Danio rerio 57733 R-DRE-1855163 https://reactome.org/PathwayBrowser/#/R-DRE-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Danio rerio 57733 R-DRE-1855166 https://reactome.org/PathwayBrowser/#/R-DRE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Danio rerio 57733 R-DRE-1855176 https://reactome.org/PathwayBrowser/#/R-DRE-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Danio rerio 57733 R-DRE-1855179 https://reactome.org/PathwayBrowser/#/R-DRE-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Danio rerio 57733 R-DRE-1855181 https://reactome.org/PathwayBrowser/#/R-DRE-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Danio rerio 57733 R-DRE-1855185 https://reactome.org/PathwayBrowser/#/R-DRE-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 57733 R-DRE-1855206 https://reactome.org/PathwayBrowser/#/R-DRE-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 57733 R-DRE-1855219 https://reactome.org/PathwayBrowser/#/R-DRE-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Danio rerio 57733 R-DRE-1855223 https://reactome.org/PathwayBrowser/#/R-DRE-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Danio rerio 57733 R-DRE-1855228 https://reactome.org/PathwayBrowser/#/R-DRE-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 57733 R-DRE-994137 https://reactome.org/PathwayBrowser/#/R-DRE-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Danio rerio 57733 R-GGA-1855162 https://reactome.org/PathwayBrowser/#/R-GGA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Gallus gallus 57733 R-GGA-1855163 https://reactome.org/PathwayBrowser/#/R-GGA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Gallus gallus 57733 R-GGA-1855166 https://reactome.org/PathwayBrowser/#/R-GGA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Gallus gallus 57733 R-GGA-1855176 https://reactome.org/PathwayBrowser/#/R-GGA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Gallus gallus 57733 R-GGA-1855179 https://reactome.org/PathwayBrowser/#/R-GGA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Gallus gallus 57733 R-GGA-1855181 https://reactome.org/PathwayBrowser/#/R-GGA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Gallus gallus 57733 R-GGA-1855185 https://reactome.org/PathwayBrowser/#/R-GGA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 57733 R-GGA-1855206 https://reactome.org/PathwayBrowser/#/R-GGA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 57733 R-GGA-1855219 https://reactome.org/PathwayBrowser/#/R-GGA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 57733 R-GGA-1855223 https://reactome.org/PathwayBrowser/#/R-GGA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Gallus gallus 57733 R-GGA-1855228 https://reactome.org/PathwayBrowser/#/R-GGA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 57733 R-GGA-994137 https://reactome.org/PathwayBrowser/#/R-GGA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Gallus gallus 57733 R-HSA-1855155 https://reactome.org/PathwayBrowser/#/R-HSA-1855155 I(1,3,4,5,6)P5 transports from the ER lumen to the cytosol TAS Homo sapiens 57733 R-HSA-1855160 https://reactome.org/PathwayBrowser/#/R-HSA-1855160 I(1,3,4,5,6)P5 transports from the ER lumen to the nucleus TAS Homo sapiens 57733 R-HSA-1855161 https://reactome.org/PathwayBrowser/#/R-HSA-1855161 I(1,3,4,5,6)P5 transports from the nucleus to the cytosol TAS Homo sapiens 57733 R-HSA-1855162 https://reactome.org/PathwayBrowser/#/R-HSA-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol TAS Homo sapiens 57733 R-HSA-1855163 https://reactome.org/PathwayBrowser/#/R-HSA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen TAS Homo sapiens 57733 R-HSA-1855166 https://reactome.org/PathwayBrowser/#/R-HSA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol TAS Homo sapiens 57733 R-HSA-1855176 https://reactome.org/PathwayBrowser/#/R-HSA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus TAS Homo sapiens 57733 R-HSA-1855179 https://reactome.org/PathwayBrowser/#/R-HSA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol TAS Homo sapiens 57733 R-HSA-1855181 https://reactome.org/PathwayBrowser/#/R-HSA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus TAS Homo sapiens 57733 R-HSA-1855185 https://reactome.org/PathwayBrowser/#/R-HSA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 57733 R-HSA-1855195 https://reactome.org/PathwayBrowser/#/R-HSA-1855195 I(1,3,4,5,6)P5 transports from the cytosol to the ER lumen TAS Homo sapiens 57733 R-HSA-1855206 https://reactome.org/PathwayBrowser/#/R-HSA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 57733 R-HSA-1855219 https://reactome.org/PathwayBrowser/#/R-HSA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 57733 R-HSA-1855223 https://reactome.org/PathwayBrowser/#/R-HSA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol TAS Homo sapiens 57733 R-HSA-1855228 https://reactome.org/PathwayBrowser/#/R-HSA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 57733 R-HSA-5357927 https://reactome.org/PathwayBrowser/#/R-HSA-5357927 MLKL oligomerizes TAS Homo sapiens 57733 R-HSA-9687638 https://reactome.org/PathwayBrowser/#/R-HSA-9687638 MLKL binds IP4, IP5 and IP6 TAS Homo sapiens 57733 R-HSA-994137 https://reactome.org/PathwayBrowser/#/R-HSA-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 TAS Homo sapiens 57733 R-MMU-1855162 https://reactome.org/PathwayBrowser/#/R-MMU-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Mus musculus 57733 R-MMU-1855163 https://reactome.org/PathwayBrowser/#/R-MMU-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Mus musculus 57733 R-MMU-1855166 https://reactome.org/PathwayBrowser/#/R-MMU-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Mus musculus 57733 R-MMU-1855176 https://reactome.org/PathwayBrowser/#/R-MMU-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Mus musculus 57733 R-MMU-1855179 https://reactome.org/PathwayBrowser/#/R-MMU-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Mus musculus 57733 R-MMU-1855181 https://reactome.org/PathwayBrowser/#/R-MMU-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Mus musculus 57733 R-MMU-1855185 https://reactome.org/PathwayBrowser/#/R-MMU-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 57733 R-MMU-1855206 https://reactome.org/PathwayBrowser/#/R-MMU-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 57733 R-MMU-1855219 https://reactome.org/PathwayBrowser/#/R-MMU-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Mus musculus 57733 R-MMU-1855223 https://reactome.org/PathwayBrowser/#/R-MMU-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Mus musculus 57733 R-MMU-1855228 https://reactome.org/PathwayBrowser/#/R-MMU-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 57733 R-MMU-9687638 https://reactome.org/PathwayBrowser/#/R-MMU-9687638 MLKL binds IP4, IP5 and IP6 IEA Mus musculus 57733 R-MMU-994137 https://reactome.org/PathwayBrowser/#/R-MMU-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Mus musculus 57733 R-PFA-1855181 https://reactome.org/PathwayBrowser/#/R-PFA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 57733 R-PFA-1855185 https://reactome.org/PathwayBrowser/#/R-PFA-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 57733 R-PFA-1855206 https://reactome.org/PathwayBrowser/#/R-PFA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 57733 R-PFA-1855223 https://reactome.org/PathwayBrowser/#/R-PFA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 57733 R-PFA-1855228 https://reactome.org/PathwayBrowser/#/R-PFA-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 57733 R-RNO-1855162 https://reactome.org/PathwayBrowser/#/R-RNO-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Rattus norvegicus 57733 R-RNO-1855163 https://reactome.org/PathwayBrowser/#/R-RNO-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Rattus norvegicus 57733 R-RNO-1855166 https://reactome.org/PathwayBrowser/#/R-RNO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Rattus norvegicus 57733 R-RNO-1855176 https://reactome.org/PathwayBrowser/#/R-RNO-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Rattus norvegicus 57733 R-RNO-1855179 https://reactome.org/PathwayBrowser/#/R-RNO-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Rattus norvegicus 57733 R-RNO-1855181 https://reactome.org/PathwayBrowser/#/R-RNO-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Rattus norvegicus 57733 R-RNO-1855185 https://reactome.org/PathwayBrowser/#/R-RNO-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 57733 R-RNO-1855206 https://reactome.org/PathwayBrowser/#/R-RNO-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 57733 R-RNO-1855219 https://reactome.org/PathwayBrowser/#/R-RNO-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 57733 R-RNO-1855223 https://reactome.org/PathwayBrowser/#/R-RNO-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Rattus norvegicus 57733 R-RNO-1855228 https://reactome.org/PathwayBrowser/#/R-RNO-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 57733 R-RNO-9687638 https://reactome.org/PathwayBrowser/#/R-RNO-9687638 MLKL binds IP4, IP5 and IP6 IEA Rattus norvegicus 57733 R-RNO-994137 https://reactome.org/PathwayBrowser/#/R-RNO-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Rattus norvegicus 57733 R-SCE-1855166 https://reactome.org/PathwayBrowser/#/R-SCE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Saccharomyces cerevisiae 57733 R-SCE-1855181 https://reactome.org/PathwayBrowser/#/R-SCE-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 57733 R-SCE-1855223 https://reactome.org/PathwayBrowser/#/R-SCE-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 57733 R-SPO-1855166 https://reactome.org/PathwayBrowser/#/R-SPO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Schizosaccharomyces pombe 57733 R-SPO-1855181 https://reactome.org/PathwayBrowser/#/R-SPO-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 57733 R-SPO-1855223 https://reactome.org/PathwayBrowser/#/R-SPO-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 57733 R-SSC-1855162 https://reactome.org/PathwayBrowser/#/R-SSC-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Sus scrofa 57733 R-SSC-1855163 https://reactome.org/PathwayBrowser/#/R-SSC-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Sus scrofa 57733 R-SSC-1855166 https://reactome.org/PathwayBrowser/#/R-SSC-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Sus scrofa 57733 R-SSC-1855176 https://reactome.org/PathwayBrowser/#/R-SSC-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Sus scrofa 57733 R-SSC-1855179 https://reactome.org/PathwayBrowser/#/R-SSC-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Sus scrofa 57733 R-SSC-1855181 https://reactome.org/PathwayBrowser/#/R-SSC-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Sus scrofa 57733 R-SSC-1855219 https://reactome.org/PathwayBrowser/#/R-SSC-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 57733 R-SSC-1855223 https://reactome.org/PathwayBrowser/#/R-SSC-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Sus scrofa 57733 R-SSC-9687638 https://reactome.org/PathwayBrowser/#/R-SSC-9687638 MLKL binds IP4, IP5 and IP6 IEA Sus scrofa 57733 R-SSC-994137 https://reactome.org/PathwayBrowser/#/R-SSC-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Sus scrofa 57733 R-XTR-1855162 https://reactome.org/PathwayBrowser/#/R-XTR-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Xenopus tropicalis 57733 R-XTR-1855163 https://reactome.org/PathwayBrowser/#/R-XTR-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Xenopus tropicalis 57733 R-XTR-1855166 https://reactome.org/PathwayBrowser/#/R-XTR-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Xenopus tropicalis 57733 R-XTR-1855176 https://reactome.org/PathwayBrowser/#/R-XTR-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Xenopus tropicalis 57733 R-XTR-1855179 https://reactome.org/PathwayBrowser/#/R-XTR-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Xenopus tropicalis 57733 R-XTR-1855181 https://reactome.org/PathwayBrowser/#/R-XTR-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 57733 R-XTR-1855185 https://reactome.org/PathwayBrowser/#/R-XTR-1855185 I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 57733 R-XTR-1855206 https://reactome.org/PathwayBrowser/#/R-XTR-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 57733 R-XTR-1855219 https://reactome.org/PathwayBrowser/#/R-XTR-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 57733 R-XTR-1855223 https://reactome.org/PathwayBrowser/#/R-XTR-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 57733 R-XTR-1855228 https://reactome.org/PathwayBrowser/#/R-XTR-1855228 I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 57733 R-XTR-994137 https://reactome.org/PathwayBrowser/#/R-XTR-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Xenopus tropicalis 57737 R-BTA-163741 https://reactome.org/PathwayBrowser/#/R-BTA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Bos taurus 57737 R-BTA-163751 https://reactome.org/PathwayBrowser/#/R-BTA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Bos taurus 57737 R-BTA-199803 https://reactome.org/PathwayBrowser/#/R-BTA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Bos taurus 57737 R-BTA-5662466 https://reactome.org/PathwayBrowser/#/R-BTA-5662466 XYLB phosphorylates D-xylulose IEA Bos taurus 57737 R-BTA-71303 https://reactome.org/PathwayBrowser/#/R-BTA-71303 RPE dimers isomerise RU5P to XY5P IEA Bos taurus 57737 R-BTA-71324 https://reactome.org/PathwayBrowser/#/R-BTA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 57737 R-BTA-71335 https://reactome.org/PathwayBrowser/#/R-BTA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Bos taurus 57737 R-CEL-163741 https://reactome.org/PathwayBrowser/#/R-CEL-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Caenorhabditis elegans 57737 R-CEL-163751 https://reactome.org/PathwayBrowser/#/R-CEL-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Caenorhabditis elegans 57737 R-CEL-199803 https://reactome.org/PathwayBrowser/#/R-CEL-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Caenorhabditis elegans 57737 R-CEL-5662466 https://reactome.org/PathwayBrowser/#/R-CEL-5662466 XYLB phosphorylates D-xylulose IEA Caenorhabditis elegans 57737 R-CEL-71303 https://reactome.org/PathwayBrowser/#/R-CEL-71303 RPE dimers isomerise RU5P to XY5P IEA Caenorhabditis elegans 57737 R-CEL-71324 https://reactome.org/PathwayBrowser/#/R-CEL-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 57737 R-CEL-71335 https://reactome.org/PathwayBrowser/#/R-CEL-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Caenorhabditis elegans 57737 R-CFA-163741 https://reactome.org/PathwayBrowser/#/R-CFA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Canis familiaris 57737 R-CFA-163751 https://reactome.org/PathwayBrowser/#/R-CFA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Canis familiaris 57737 R-CFA-199803 https://reactome.org/PathwayBrowser/#/R-CFA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Canis familiaris 57737 R-CFA-5662466 https://reactome.org/PathwayBrowser/#/R-CFA-5662466 XYLB phosphorylates D-xylulose IEA Canis familiaris 57737 R-CFA-71303 https://reactome.org/PathwayBrowser/#/R-CFA-71303 RPE dimers isomerise RU5P to XY5P IEA Canis familiaris 57737 R-CFA-71324 https://reactome.org/PathwayBrowser/#/R-CFA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 57737 R-CFA-71335 https://reactome.org/PathwayBrowser/#/R-CFA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Canis familiaris 57737 R-DDI-199803 https://reactome.org/PathwayBrowser/#/R-DDI-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Dictyostelium discoideum 57737 R-DDI-71303 https://reactome.org/PathwayBrowser/#/R-DDI-71303 RPE dimers isomerise RU5P to XY5P IEA Dictyostelium discoideum 57737 R-DME-163741 https://reactome.org/PathwayBrowser/#/R-DME-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Drosophila melanogaster 57737 R-DME-163751 https://reactome.org/PathwayBrowser/#/R-DME-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Drosophila melanogaster 57737 R-DME-199803 https://reactome.org/PathwayBrowser/#/R-DME-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Drosophila melanogaster 57737 R-DME-5662466 https://reactome.org/PathwayBrowser/#/R-DME-5662466 XYLB phosphorylates D-xylulose IEA Drosophila melanogaster 57737 R-DME-71303 https://reactome.org/PathwayBrowser/#/R-DME-71303 RPE dimers isomerise RU5P to XY5P IEA Drosophila melanogaster 57737 R-DME-71324 https://reactome.org/PathwayBrowser/#/R-DME-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 57737 R-DME-71335 https://reactome.org/PathwayBrowser/#/R-DME-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Drosophila melanogaster 57737 R-DRE-199803 https://reactome.org/PathwayBrowser/#/R-DRE-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Danio rerio 57737 R-DRE-5662466 https://reactome.org/PathwayBrowser/#/R-DRE-5662466 XYLB phosphorylates D-xylulose IEA Danio rerio 57737 R-DRE-71303 https://reactome.org/PathwayBrowser/#/R-DRE-71303 RPE dimers isomerise RU5P to XY5P IEA Danio rerio 57737 R-GGA-163741 https://reactome.org/PathwayBrowser/#/R-GGA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Gallus gallus 57737 R-GGA-163751 https://reactome.org/PathwayBrowser/#/R-GGA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Gallus gallus 57737 R-GGA-199803 https://reactome.org/PathwayBrowser/#/R-GGA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Gallus gallus 57737 R-GGA-5662466 https://reactome.org/PathwayBrowser/#/R-GGA-5662466 XYLB phosphorylates D-xylulose IEA Gallus gallus 57737 R-GGA-71303 https://reactome.org/PathwayBrowser/#/R-GGA-71303 RPE dimers isomerise RU5P to XY5P IEA Gallus gallus 57737 R-GGA-71324 https://reactome.org/PathwayBrowser/#/R-GGA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 57737 R-GGA-71335 https://reactome.org/PathwayBrowser/#/R-GGA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Gallus gallus 57737 R-HSA-163741 https://reactome.org/PathwayBrowser/#/R-HSA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate TAS Homo sapiens 57737 R-HSA-163751 https://reactome.org/PathwayBrowser/#/R-HSA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate TAS Homo sapiens 57737 R-HSA-163769 https://reactome.org/PathwayBrowser/#/R-HSA-163769 Activation of PP2A by Xylulose-5-phosphate IEA Homo sapiens 57737 R-HSA-199803 https://reactome.org/PathwayBrowser/#/R-HSA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate TAS Homo sapiens 57737 R-HSA-5662466 https://reactome.org/PathwayBrowser/#/R-HSA-5662466 XYLB phosphorylates D-xylulose TAS Homo sapiens 57737 R-HSA-71303 https://reactome.org/PathwayBrowser/#/R-HSA-71303 RPE dimers isomerise RU5P to XY5P TAS Homo sapiens 57737 R-HSA-71324 https://reactome.org/PathwayBrowser/#/R-HSA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 57737 R-HSA-71335 https://reactome.org/PathwayBrowser/#/R-HSA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate TAS Homo sapiens 57737 R-MMU-163741 https://reactome.org/PathwayBrowser/#/R-MMU-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Mus musculus 57737 R-MMU-163751 https://reactome.org/PathwayBrowser/#/R-MMU-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Mus musculus 57737 R-MMU-199803 https://reactome.org/PathwayBrowser/#/R-MMU-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Mus musculus 57737 R-MMU-5662466 https://reactome.org/PathwayBrowser/#/R-MMU-5662466 XYLB phosphorylates D-xylulose IEA Mus musculus 57737 R-MMU-71303 https://reactome.org/PathwayBrowser/#/R-MMU-71303 RPE dimers isomerise RU5P to XY5P IEA Mus musculus 57737 R-MMU-71324 https://reactome.org/PathwayBrowser/#/R-MMU-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 57737 R-MMU-71335 https://reactome.org/PathwayBrowser/#/R-MMU-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Mus musculus 57737 R-PFA-199803 https://reactome.org/PathwayBrowser/#/R-PFA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Plasmodium falciparum 57737 R-PFA-71303 https://reactome.org/PathwayBrowser/#/R-PFA-71303 RPE dimers isomerise RU5P to XY5P IEA Plasmodium falciparum 57737 R-RNO-163741 https://reactome.org/PathwayBrowser/#/R-RNO-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Rattus norvegicus 57737 R-RNO-163751 https://reactome.org/PathwayBrowser/#/R-RNO-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Rattus norvegicus 57737 R-RNO-199803 https://reactome.org/PathwayBrowser/#/R-RNO-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Rattus norvegicus 57737 R-RNO-5662466 https://reactome.org/PathwayBrowser/#/R-RNO-5662466 XYLB phosphorylates D-xylulose IEA Rattus norvegicus 57737 R-RNO-71303 https://reactome.org/PathwayBrowser/#/R-RNO-71303 RPE dimers isomerise RU5P to XY5P IEA Rattus norvegicus 57737 R-RNO-71324 https://reactome.org/PathwayBrowser/#/R-RNO-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 57737 R-RNO-71335 https://reactome.org/PathwayBrowser/#/R-RNO-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Rattus norvegicus 57737 R-SCE-199803 https://reactome.org/PathwayBrowser/#/R-SCE-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Saccharomyces cerevisiae 57737 R-SCE-5662466 https://reactome.org/PathwayBrowser/#/R-SCE-5662466 XYLB phosphorylates D-xylulose IEA Saccharomyces cerevisiae 57737 R-SCE-71303 https://reactome.org/PathwayBrowser/#/R-SCE-71303 RPE dimers isomerise RU5P to XY5P IEA Saccharomyces cerevisiae 57737 R-SPO-199803 https://reactome.org/PathwayBrowser/#/R-SPO-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Schizosaccharomyces pombe 57737 R-SPO-5662466 https://reactome.org/PathwayBrowser/#/R-SPO-5662466 XYLB phosphorylates D-xylulose IEA Schizosaccharomyces pombe 57737 R-SPO-71303 https://reactome.org/PathwayBrowser/#/R-SPO-71303 RPE dimers isomerise RU5P to XY5P IEA Schizosaccharomyces pombe 57737 R-SSC-163741 https://reactome.org/PathwayBrowser/#/R-SSC-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Sus scrofa 57737 R-SSC-163751 https://reactome.org/PathwayBrowser/#/R-SSC-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Sus scrofa 57737 R-SSC-199803 https://reactome.org/PathwayBrowser/#/R-SSC-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Sus scrofa 57737 R-SSC-5662466 https://reactome.org/PathwayBrowser/#/R-SSC-5662466 XYLB phosphorylates D-xylulose IEA Sus scrofa 57737 R-SSC-71303 https://reactome.org/PathwayBrowser/#/R-SSC-71303 RPE dimers isomerise RU5P to XY5P IEA Sus scrofa 57737 R-SSC-71324 https://reactome.org/PathwayBrowser/#/R-SSC-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 57737 R-SSC-71335 https://reactome.org/PathwayBrowser/#/R-SSC-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Sus scrofa 57737 R-XTR-163741 https://reactome.org/PathwayBrowser/#/R-XTR-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Xenopus tropicalis 57737 R-XTR-163751 https://reactome.org/PathwayBrowser/#/R-XTR-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Xenopus tropicalis 57737 R-XTR-199803 https://reactome.org/PathwayBrowser/#/R-XTR-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Xenopus tropicalis 57737 R-XTR-5662466 https://reactome.org/PathwayBrowser/#/R-XTR-5662466 XYLB phosphorylates D-xylulose IEA Xenopus tropicalis 57737 R-XTR-71303 https://reactome.org/PathwayBrowser/#/R-XTR-71303 RPE dimers isomerise RU5P to XY5P IEA Xenopus tropicalis 57737 R-XTR-71324 https://reactome.org/PathwayBrowser/#/R-XTR-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 57737 R-XTR-71335 https://reactome.org/PathwayBrowser/#/R-XTR-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Xenopus tropicalis 57739 R-BTA-1482548 https://reactome.org/PathwayBrowser/#/R-BTA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Bos taurus 57739 R-BTA-1482604 https://reactome.org/PathwayBrowser/#/R-BTA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Bos taurus 57739 R-BTA-1482656 https://reactome.org/PathwayBrowser/#/R-BTA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Bos taurus 57739 R-BTA-1482679 https://reactome.org/PathwayBrowser/#/R-BTA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Bos taurus 57739 R-BTA-1483121 https://reactome.org/PathwayBrowser/#/R-BTA-1483121 PA is converted to CDP-DAG by CDS1 IEA Bos taurus 57739 R-BTA-1483165 https://reactome.org/PathwayBrowser/#/R-BTA-1483165 PA is converted to CDP-DAG by CDS2 IEA Bos taurus 57739 R-BTA-1483182 https://reactome.org/PathwayBrowser/#/R-BTA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Bos taurus 57739 R-BTA-1483203 https://reactome.org/PathwayBrowser/#/R-BTA-1483203 PA is dephosphorylated to DAG by LPIN IEA Bos taurus 57739 R-BTA-1602446 https://reactome.org/PathwayBrowser/#/R-BTA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Bos taurus 57739 R-BTA-2029468 https://reactome.org/PathwayBrowser/#/R-BTA-2029468 Conversion of PA into DAG by PAP-1 IEA Bos taurus 57739 R-BTA-2029471 https://reactome.org/PathwayBrowser/#/R-BTA-2029471 Hydrolysis of PC to PA by PLD IEA Bos taurus 57739 R-BTA-5696074 https://reactome.org/PathwayBrowser/#/R-BTA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Bos taurus 57739 R-BTA-6786650 https://reactome.org/PathwayBrowser/#/R-BTA-6786650 DDHD1,2 hydrolyse PA IEA Bos taurus 57739 R-BTA-6792445 https://reactome.org/PathwayBrowser/#/R-BTA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Bos taurus 57739 R-BTA-6801250 https://reactome.org/PathwayBrowser/#/R-BTA-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Bos taurus 57739 R-BTA-75885 https://reactome.org/PathwayBrowser/#/R-BTA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Bos taurus 57739 R-BTA-8869241 https://reactome.org/PathwayBrowser/#/R-BTA-8869241 PITPNM1,2,3 exchange PI for PA IEA Bos taurus 57739 R-BTA-8954398 https://reactome.org/PathwayBrowser/#/R-BTA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Bos taurus 57739 R-CEL-1482548 https://reactome.org/PathwayBrowser/#/R-CEL-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Caenorhabditis elegans 57739 R-CEL-1482604 https://reactome.org/PathwayBrowser/#/R-CEL-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Caenorhabditis elegans 57739 R-CEL-1482656 https://reactome.org/PathwayBrowser/#/R-CEL-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Caenorhabditis elegans 57739 R-CEL-1482679 https://reactome.org/PathwayBrowser/#/R-CEL-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Caenorhabditis elegans 57739 R-CEL-1483121 https://reactome.org/PathwayBrowser/#/R-CEL-1483121 PA is converted to CDP-DAG by CDS1 IEA Caenorhabditis elegans 57739 R-CEL-1483165 https://reactome.org/PathwayBrowser/#/R-CEL-1483165 PA is converted to CDP-DAG by CDS2 IEA Caenorhabditis elegans 57739 R-CEL-1483182 https://reactome.org/PathwayBrowser/#/R-CEL-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Caenorhabditis elegans 57739 R-CEL-1483203 https://reactome.org/PathwayBrowser/#/R-CEL-1483203 PA is dephosphorylated to DAG by LPIN IEA Caenorhabditis elegans 57739 R-CEL-1602446 https://reactome.org/PathwayBrowser/#/R-CEL-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Caenorhabditis elegans 57739 R-CEL-2029471 https://reactome.org/PathwayBrowser/#/R-CEL-2029471 Hydrolysis of PC to PA by PLD IEA Caenorhabditis elegans 57739 R-CEL-5696074 https://reactome.org/PathwayBrowser/#/R-CEL-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Caenorhabditis elegans 57739 R-CEL-75885 https://reactome.org/PathwayBrowser/#/R-CEL-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Caenorhabditis elegans 57739 R-CEL-8869241 https://reactome.org/PathwayBrowser/#/R-CEL-8869241 PITPNM1,2,3 exchange PI for PA IEA Caenorhabditis elegans 57739 R-CFA-1482548 https://reactome.org/PathwayBrowser/#/R-CFA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Canis familiaris 57739 R-CFA-1482604 https://reactome.org/PathwayBrowser/#/R-CFA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Canis familiaris 57739 R-CFA-1482656 https://reactome.org/PathwayBrowser/#/R-CFA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Canis familiaris 57739 R-CFA-1483121 https://reactome.org/PathwayBrowser/#/R-CFA-1483121 PA is converted to CDP-DAG by CDS1 IEA Canis familiaris 57739 R-CFA-1483165 https://reactome.org/PathwayBrowser/#/R-CFA-1483165 PA is converted to CDP-DAG by CDS2 IEA Canis familiaris 57739 R-CFA-1483182 https://reactome.org/PathwayBrowser/#/R-CFA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Canis familiaris 57739 R-CFA-1483203 https://reactome.org/PathwayBrowser/#/R-CFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Canis familiaris 57739 R-CFA-1602446 https://reactome.org/PathwayBrowser/#/R-CFA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Canis familiaris 57739 R-CFA-2029468 https://reactome.org/PathwayBrowser/#/R-CFA-2029468 Conversion of PA into DAG by PAP-1 IEA Canis familiaris 57739 R-CFA-2029471 https://reactome.org/PathwayBrowser/#/R-CFA-2029471 Hydrolysis of PC to PA by PLD IEA Canis familiaris 57739 R-CFA-5696074 https://reactome.org/PathwayBrowser/#/R-CFA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Canis familiaris 57739 R-CFA-6786650 https://reactome.org/PathwayBrowser/#/R-CFA-6786650 DDHD1,2 hydrolyse PA IEA Canis familiaris 57739 R-CFA-6792445 https://reactome.org/PathwayBrowser/#/R-CFA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Canis familiaris 57739 R-CFA-6801250 https://reactome.org/PathwayBrowser/#/R-CFA-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Canis familiaris 57739 R-CFA-75885 https://reactome.org/PathwayBrowser/#/R-CFA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Canis familiaris 57739 R-CFA-8869241 https://reactome.org/PathwayBrowser/#/R-CFA-8869241 PITPNM1,2,3 exchange PI for PA IEA Canis familiaris 57739 R-CFA-8954398 https://reactome.org/PathwayBrowser/#/R-CFA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Canis familiaris 57739 R-DDI-1482548 https://reactome.org/PathwayBrowser/#/R-DDI-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Dictyostelium discoideum 57739 R-DDI-1483121 https://reactome.org/PathwayBrowser/#/R-DDI-1483121 PA is converted to CDP-DAG by CDS1 IEA Dictyostelium discoideum 57739 R-DDI-1483165 https://reactome.org/PathwayBrowser/#/R-DDI-1483165 PA is converted to CDP-DAG by CDS2 IEA Dictyostelium discoideum 57739 R-DDI-1483182 https://reactome.org/PathwayBrowser/#/R-DDI-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Dictyostelium discoideum 57739 R-DDI-1483203 https://reactome.org/PathwayBrowser/#/R-DDI-1483203 PA is dephosphorylated to DAG by LPIN IEA Dictyostelium discoideum 57739 R-DDI-2029468 https://reactome.org/PathwayBrowser/#/R-DDI-2029468 Conversion of PA into DAG by PAP-1 IEA Dictyostelium discoideum 57739 R-DDI-2029471 https://reactome.org/PathwayBrowser/#/R-DDI-2029471 Hydrolysis of PC to PA by PLD IEA Dictyostelium discoideum 57739 R-DDI-5696074 https://reactome.org/PathwayBrowser/#/R-DDI-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Dictyostelium discoideum 57739 R-DDI-6786650 https://reactome.org/PathwayBrowser/#/R-DDI-6786650 DDHD1,2 hydrolyse PA IEA Dictyostelium discoideum 57739 R-DDI-6801250 https://reactome.org/PathwayBrowser/#/R-DDI-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Dictyostelium discoideum 57739 R-DDI-75885 https://reactome.org/PathwayBrowser/#/R-DDI-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Dictyostelium discoideum 57739 R-DDI-8869241 https://reactome.org/PathwayBrowser/#/R-DDI-8869241 PITPNM1,2,3 exchange PI for PA IEA Dictyostelium discoideum 57739 R-DDI-8954398 https://reactome.org/PathwayBrowser/#/R-DDI-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Dictyostelium discoideum 57739 R-DME-1482604 https://reactome.org/PathwayBrowser/#/R-DME-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Drosophila melanogaster 57739 R-DME-1482656 https://reactome.org/PathwayBrowser/#/R-DME-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Drosophila melanogaster 57739 R-DME-1482679 https://reactome.org/PathwayBrowser/#/R-DME-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Drosophila melanogaster 57739 R-DME-1483121 https://reactome.org/PathwayBrowser/#/R-DME-1483121 PA is converted to CDP-DAG by CDS1 IEA Drosophila melanogaster 57739 R-DME-1483165 https://reactome.org/PathwayBrowser/#/R-DME-1483165 PA is converted to CDP-DAG by CDS2 IEA Drosophila melanogaster 57739 R-DME-1483182 https://reactome.org/PathwayBrowser/#/R-DME-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Drosophila melanogaster 57739 R-DME-1483203 https://reactome.org/PathwayBrowser/#/R-DME-1483203 PA is dephosphorylated to DAG by LPIN IEA Drosophila melanogaster 57739 R-DME-1602446 https://reactome.org/PathwayBrowser/#/R-DME-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Drosophila melanogaster 57739 R-DME-2029468 https://reactome.org/PathwayBrowser/#/R-DME-2029468 Conversion of PA into DAG by PAP-1 IEA Drosophila melanogaster 57739 R-DME-2029471 https://reactome.org/PathwayBrowser/#/R-DME-2029471 Hydrolysis of PC to PA by PLD IEA Drosophila melanogaster 57739 R-DME-5696074 https://reactome.org/PathwayBrowser/#/R-DME-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Drosophila melanogaster 57739 R-DME-6792445 https://reactome.org/PathwayBrowser/#/R-DME-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Drosophila melanogaster 57739 R-DME-6801250 https://reactome.org/PathwayBrowser/#/R-DME-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Drosophila melanogaster 57739 R-DME-75885 https://reactome.org/PathwayBrowser/#/R-DME-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Drosophila melanogaster 57739 R-DME-8869241 https://reactome.org/PathwayBrowser/#/R-DME-8869241 PITPNM1,2,3 exchange PI for PA IEA Drosophila melanogaster 57739 R-DME-8954398 https://reactome.org/PathwayBrowser/#/R-DME-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Drosophila melanogaster 57739 R-DRE-1482604 https://reactome.org/PathwayBrowser/#/R-DRE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Danio rerio 57739 R-DRE-1482656 https://reactome.org/PathwayBrowser/#/R-DRE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Danio rerio 57739 R-DRE-1483165 https://reactome.org/PathwayBrowser/#/R-DRE-1483165 PA is converted to CDP-DAG by CDS2 IEA Danio rerio 57739 R-DRE-1483203 https://reactome.org/PathwayBrowser/#/R-DRE-1483203 PA is dephosphorylated to DAG by LPIN IEA Danio rerio 57739 R-DRE-1602446 https://reactome.org/PathwayBrowser/#/R-DRE-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Danio rerio 57739 R-DRE-5696074 https://reactome.org/PathwayBrowser/#/R-DRE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Danio rerio 57739 R-DRE-6792445 https://reactome.org/PathwayBrowser/#/R-DRE-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Danio rerio 57739 R-DRE-75885 https://reactome.org/PathwayBrowser/#/R-DRE-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Danio rerio 57739 R-DRE-8954398 https://reactome.org/PathwayBrowser/#/R-DRE-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Danio rerio 57739 R-GGA-1482548 https://reactome.org/PathwayBrowser/#/R-GGA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Gallus gallus 57739 R-GGA-1482604 https://reactome.org/PathwayBrowser/#/R-GGA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Gallus gallus 57739 R-GGA-1482656 https://reactome.org/PathwayBrowser/#/R-GGA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Gallus gallus 57739 R-GGA-1482679 https://reactome.org/PathwayBrowser/#/R-GGA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Gallus gallus 57739 R-GGA-1483121 https://reactome.org/PathwayBrowser/#/R-GGA-1483121 PA is converted to CDP-DAG by CDS1 IEA Gallus gallus 57739 R-GGA-1483165 https://reactome.org/PathwayBrowser/#/R-GGA-1483165 PA is converted to CDP-DAG by CDS2 IEA Gallus gallus 57739 R-GGA-1483182 https://reactome.org/PathwayBrowser/#/R-GGA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Gallus gallus 57739 R-GGA-1483203 https://reactome.org/PathwayBrowser/#/R-GGA-1483203 PA is dephosphorylated to DAG by LPIN IEA Gallus gallus 57739 R-GGA-1602446 https://reactome.org/PathwayBrowser/#/R-GGA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Gallus gallus 57739 R-GGA-2029468 https://reactome.org/PathwayBrowser/#/R-GGA-2029468 Conversion of PA into DAG by PAP-1 IEA Gallus gallus 57739 R-GGA-5696074 https://reactome.org/PathwayBrowser/#/R-GGA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Gallus gallus 57739 R-GGA-6786650 https://reactome.org/PathwayBrowser/#/R-GGA-6786650 DDHD1,2 hydrolyse PA IEA Gallus gallus 57739 R-GGA-6792445 https://reactome.org/PathwayBrowser/#/R-GGA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Gallus gallus 57739 R-GGA-6801250 https://reactome.org/PathwayBrowser/#/R-GGA-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Gallus gallus 57739 R-GGA-75885 https://reactome.org/PathwayBrowser/#/R-GGA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Gallus gallus 57739 R-GGA-8869241 https://reactome.org/PathwayBrowser/#/R-GGA-8869241 PITPNM1,2,3 exchange PI for PA IEA Gallus gallus 57739 R-GGA-8954398 https://reactome.org/PathwayBrowser/#/R-GGA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Gallus gallus 57739 R-HSA-1482548 https://reactome.org/PathwayBrowser/#/R-HSA-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) TAS Homo sapiens 57739 R-HSA-1482604 https://reactome.org/PathwayBrowser/#/R-HSA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) TAS Homo sapiens 57739 R-HSA-1482656 https://reactome.org/PathwayBrowser/#/R-HSA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] TAS Homo sapiens 57739 R-HSA-1482679 https://reactome.org/PathwayBrowser/#/R-HSA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A TAS Homo sapiens 57739 R-HSA-1483099 https://reactome.org/PathwayBrowser/#/R-HSA-1483099 PA translocates from the outer to the inner mitochondrial membrane IEA Homo sapiens 57739 R-HSA-1483121 https://reactome.org/PathwayBrowser/#/R-HSA-1483121 PA is converted to CDP-DAG by CDS1 TAS Homo sapiens 57739 R-HSA-1483165 https://reactome.org/PathwayBrowser/#/R-HSA-1483165 PA is converted to CDP-DAG by CDS2 TAS Homo sapiens 57739 R-HSA-1483182 https://reactome.org/PathwayBrowser/#/R-HSA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 TAS Homo sapiens 57739 R-HSA-1483203 https://reactome.org/PathwayBrowser/#/R-HSA-1483203 PA is dephosphorylated to DAG by LPIN TAS Homo sapiens 57739 R-HSA-1602446 https://reactome.org/PathwayBrowser/#/R-HSA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] TAS Homo sapiens 57739 R-HSA-2029468 https://reactome.org/PathwayBrowser/#/R-HSA-2029468 Conversion of PA into DAG by PAP-1 TAS Homo sapiens 57739 R-HSA-2029471 https://reactome.org/PathwayBrowser/#/R-HSA-2029471 Hydrolysis of PC to PA by PLD TAS Homo sapiens 57739 R-HSA-2466831 https://reactome.org/PathwayBrowser/#/R-HSA-2466831 A2PE hydrolyses to A2E TAS Homo sapiens 57739 R-HSA-5696074 https://reactome.org/PathwayBrowser/#/R-HSA-5696074 AGK:Mg2+ phosphorylates MAG, DAG TAS Homo sapiens 57739 R-HSA-6786650 https://reactome.org/PathwayBrowser/#/R-HSA-6786650 DDHD1,2 hydrolyse PA TAS Homo sapiens 57739 R-HSA-6792445 https://reactome.org/PathwayBrowser/#/R-HSA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA TAS Homo sapiens 57739 R-HSA-6801250 https://reactome.org/PathwayBrowser/#/R-HSA-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane TAS Homo sapiens 57739 R-HSA-75885 https://reactome.org/PathwayBrowser/#/R-HSA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) TAS Homo sapiens 57739 R-HSA-8869241 https://reactome.org/PathwayBrowser/#/R-HSA-8869241 PITPNM1,2,3 exchange PI for PA TAS Homo sapiens 57739 R-HSA-8954398 https://reactome.org/PathwayBrowser/#/R-HSA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG TAS Homo sapiens 57739 R-MMU-1482548 https://reactome.org/PathwayBrowser/#/R-MMU-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Mus musculus 57739 R-MMU-1482604 https://reactome.org/PathwayBrowser/#/R-MMU-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Mus musculus 57739 R-MMU-1482656 https://reactome.org/PathwayBrowser/#/R-MMU-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Mus musculus 57739 R-MMU-1482679 https://reactome.org/PathwayBrowser/#/R-MMU-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Mus musculus 57739 R-MMU-1483121 https://reactome.org/PathwayBrowser/#/R-MMU-1483121 PA is converted to CDP-DAG by CDS1 IEA Mus musculus 57739 R-MMU-1483165 https://reactome.org/PathwayBrowser/#/R-MMU-1483165 PA is converted to CDP-DAG by CDS2 IEA Mus musculus 57739 R-MMU-1483182 https://reactome.org/PathwayBrowser/#/R-MMU-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Mus musculus 57739 R-MMU-1483203 https://reactome.org/PathwayBrowser/#/R-MMU-1483203 PA is dephosphorylated to DAG by LPIN IEA Mus musculus 57739 R-MMU-1602446 https://reactome.org/PathwayBrowser/#/R-MMU-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Mus musculus 57739 R-MMU-2029468 https://reactome.org/PathwayBrowser/#/R-MMU-2029468 Conversion of PA into DAG by PAP-1 IEA Mus musculus 57739 R-MMU-2029471 https://reactome.org/PathwayBrowser/#/R-MMU-2029471 Hydrolysis of PC to PA by PLD IEA Mus musculus 57739 R-MMU-5696074 https://reactome.org/PathwayBrowser/#/R-MMU-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Mus musculus 57739 R-MMU-6786650 https://reactome.org/PathwayBrowser/#/R-MMU-6786650 DDHD1,2 hydrolyse PA IEA Mus musculus 57739 R-MMU-6792445 https://reactome.org/PathwayBrowser/#/R-MMU-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Mus musculus 57739 R-MMU-6801250 https://reactome.org/PathwayBrowser/#/R-MMU-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Mus musculus 57739 R-MMU-75885 https://reactome.org/PathwayBrowser/#/R-MMU-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Mus musculus 57739 R-MMU-8869241 https://reactome.org/PathwayBrowser/#/R-MMU-8869241 PITPNM1,2,3 exchange PI for PA IEA Mus musculus 57739 R-MMU-8954398 https://reactome.org/PathwayBrowser/#/R-MMU-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Mus musculus 57739 R-PFA-1483121 https://reactome.org/PathwayBrowser/#/R-PFA-1483121 PA is converted to CDP-DAG by CDS1 IEA Plasmodium falciparum 57739 R-PFA-1483165 https://reactome.org/PathwayBrowser/#/R-PFA-1483165 PA is converted to CDP-DAG by CDS2 IEA Plasmodium falciparum 57739 R-PFA-1483203 https://reactome.org/PathwayBrowser/#/R-PFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Plasmodium falciparum 57739 R-PFA-6786650 https://reactome.org/PathwayBrowser/#/R-PFA-6786650 DDHD1,2 hydrolyse PA IEA Plasmodium falciparum 57739 R-PFA-6801250 https://reactome.org/PathwayBrowser/#/R-PFA-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Plasmodium falciparum 57739 R-PFA-75885 https://reactome.org/PathwayBrowser/#/R-PFA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Plasmodium falciparum 57739 R-PFA-8869241 https://reactome.org/PathwayBrowser/#/R-PFA-8869241 PITPNM1,2,3 exchange PI for PA IEA Plasmodium falciparum 57739 R-RNO-1482548 https://reactome.org/PathwayBrowser/#/R-RNO-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Rattus norvegicus 57739 R-RNO-1482604 https://reactome.org/PathwayBrowser/#/R-RNO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Rattus norvegicus 57739 R-RNO-1482656 https://reactome.org/PathwayBrowser/#/R-RNO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Rattus norvegicus 57739 R-RNO-1482679 https://reactome.org/PathwayBrowser/#/R-RNO-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Rattus norvegicus 57739 R-RNO-1483121 https://reactome.org/PathwayBrowser/#/R-RNO-1483121 PA is converted to CDP-DAG by CDS1 IEA Rattus norvegicus 57739 R-RNO-1483154 https://reactome.org/PathwayBrowser/#/R-RNO-1483154 PA transports from the outer to the inner mitochondrial membrane TAS Rattus norvegicus 57739 R-RNO-1483165 https://reactome.org/PathwayBrowser/#/R-RNO-1483165 PA is converted to CDP-DAG by CDS2 IEA Rattus norvegicus 57739 R-RNO-1483182 https://reactome.org/PathwayBrowser/#/R-RNO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Rattus norvegicus 57739 R-RNO-1483203 https://reactome.org/PathwayBrowser/#/R-RNO-1483203 PA is dephosphorylated to DAG by LPIN IEA Rattus norvegicus 57739 R-RNO-1602446 https://reactome.org/PathwayBrowser/#/R-RNO-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Rattus norvegicus 57739 R-RNO-2029468 https://reactome.org/PathwayBrowser/#/R-RNO-2029468 Conversion of PA into DAG by PAP-1 IEA Rattus norvegicus 57739 R-RNO-2029471 https://reactome.org/PathwayBrowser/#/R-RNO-2029471 Hydrolysis of PC to PA by PLD IEA Rattus norvegicus 57739 R-RNO-5696074 https://reactome.org/PathwayBrowser/#/R-RNO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Rattus norvegicus 57739 R-RNO-6786650 https://reactome.org/PathwayBrowser/#/R-RNO-6786650 DDHD1,2 hydrolyse PA IEA Rattus norvegicus 57739 R-RNO-6792445 https://reactome.org/PathwayBrowser/#/R-RNO-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Rattus norvegicus 57739 R-RNO-75885 https://reactome.org/PathwayBrowser/#/R-RNO-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Rattus norvegicus 57739 R-RNO-8869241 https://reactome.org/PathwayBrowser/#/R-RNO-8869241 PITPNM1,2,3 exchange PI for PA IEA Rattus norvegicus 57739 R-RNO-8954398 https://reactome.org/PathwayBrowser/#/R-RNO-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Rattus norvegicus 57739 R-SCE-1482604 https://reactome.org/PathwayBrowser/#/R-SCE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Saccharomyces cerevisiae 57739 R-SCE-1482656 https://reactome.org/PathwayBrowser/#/R-SCE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Saccharomyces cerevisiae 57739 R-SCE-1483121 https://reactome.org/PathwayBrowser/#/R-SCE-1483121 PA is converted to CDP-DAG by CDS1 IEA Saccharomyces cerevisiae 57739 R-SCE-1483165 https://reactome.org/PathwayBrowser/#/R-SCE-1483165 PA is converted to CDP-DAG by CDS2 IEA Saccharomyces cerevisiae 57739 R-SCE-1483182 https://reactome.org/PathwayBrowser/#/R-SCE-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Saccharomyces cerevisiae 57739 R-SCE-1483203 https://reactome.org/PathwayBrowser/#/R-SCE-1483203 PA is dephosphorylated to DAG by LPIN IEA Saccharomyces cerevisiae 57739 R-SCE-2029468 https://reactome.org/PathwayBrowser/#/R-SCE-2029468 Conversion of PA into DAG by PAP-1 IEA Saccharomyces cerevisiae 57739 R-SCE-2029471 https://reactome.org/PathwayBrowser/#/R-SCE-2029471 Hydrolysis of PC to PA by PLD IEA Saccharomyces cerevisiae 57739 R-SCE-5696074 https://reactome.org/PathwayBrowser/#/R-SCE-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Saccharomyces cerevisiae 57739 R-SCE-6786650 https://reactome.org/PathwayBrowser/#/R-SCE-6786650 DDHD1,2 hydrolyse PA IEA Saccharomyces cerevisiae 57739 R-SCE-6801250 https://reactome.org/PathwayBrowser/#/R-SCE-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Saccharomyces cerevisiae 57739 R-SCE-75885 https://reactome.org/PathwayBrowser/#/R-SCE-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Saccharomyces cerevisiae 57739 R-SCE-8869241 https://reactome.org/PathwayBrowser/#/R-SCE-8869241 PITPNM1,2,3 exchange PI for PA IEA Saccharomyces cerevisiae 57739 R-SPO-1482604 https://reactome.org/PathwayBrowser/#/R-SPO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Schizosaccharomyces pombe 57739 R-SPO-1482656 https://reactome.org/PathwayBrowser/#/R-SPO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Schizosaccharomyces pombe 57739 R-SPO-1483121 https://reactome.org/PathwayBrowser/#/R-SPO-1483121 PA is converted to CDP-DAG by CDS1 IEA Schizosaccharomyces pombe 57739 R-SPO-1483165 https://reactome.org/PathwayBrowser/#/R-SPO-1483165 PA is converted to CDP-DAG by CDS2 IEA Schizosaccharomyces pombe 57739 R-SPO-1483182 https://reactome.org/PathwayBrowser/#/R-SPO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Schizosaccharomyces pombe 57739 R-SPO-1483203 https://reactome.org/PathwayBrowser/#/R-SPO-1483203 PA is dephosphorylated to DAG by LPIN IEA Schizosaccharomyces pombe 57739 R-SPO-2029468 https://reactome.org/PathwayBrowser/#/R-SPO-2029468 Conversion of PA into DAG by PAP-1 IEA Schizosaccharomyces pombe 57739 R-SPO-2029471 https://reactome.org/PathwayBrowser/#/R-SPO-2029471 Hydrolysis of PC to PA by PLD IEA Schizosaccharomyces pombe 57739 R-SPO-5696074 https://reactome.org/PathwayBrowser/#/R-SPO-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Schizosaccharomyces pombe 57739 R-SPO-6786650 https://reactome.org/PathwayBrowser/#/R-SPO-6786650 DDHD1,2 hydrolyse PA IEA Schizosaccharomyces pombe 57739 R-SPO-6801250 https://reactome.org/PathwayBrowser/#/R-SPO-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Schizosaccharomyces pombe 57739 R-SPO-75885 https://reactome.org/PathwayBrowser/#/R-SPO-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Schizosaccharomyces pombe 57739 R-SPO-8869241 https://reactome.org/PathwayBrowser/#/R-SPO-8869241 PITPNM1,2,3 exchange PI for PA IEA Schizosaccharomyces pombe 57739 R-SSC-1482548 https://reactome.org/PathwayBrowser/#/R-SSC-1482548 1-acyl LPA is acylated to PA by AGPAT5 (OM) IEA Sus scrofa 57739 R-SSC-1482604 https://reactome.org/PathwayBrowser/#/R-SSC-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Sus scrofa 57739 R-SSC-1482656 https://reactome.org/PathwayBrowser/#/R-SSC-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Sus scrofa 57739 R-SSC-1482679 https://reactome.org/PathwayBrowser/#/R-SSC-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Sus scrofa 57739 R-SSC-1483121 https://reactome.org/PathwayBrowser/#/R-SSC-1483121 PA is converted to CDP-DAG by CDS1 IEA Sus scrofa 57739 R-SSC-1483165 https://reactome.org/PathwayBrowser/#/R-SSC-1483165 PA is converted to CDP-DAG by CDS2 IEA Sus scrofa 57739 R-SSC-1483182 https://reactome.org/PathwayBrowser/#/R-SSC-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Sus scrofa 57739 R-SSC-1483203 https://reactome.org/PathwayBrowser/#/R-SSC-1483203 PA is dephosphorylated to DAG by LPIN IEA Sus scrofa 57739 R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa 57739 R-SSC-2029468 https://reactome.org/PathwayBrowser/#/R-SSC-2029468 Conversion of PA into DAG by PAP-1 IEA Sus scrofa 57739 R-SSC-2029471 https://reactome.org/PathwayBrowser/#/R-SSC-2029471 Hydrolysis of PC to PA by PLD IEA Sus scrofa 57739 R-SSC-5696074 https://reactome.org/PathwayBrowser/#/R-SSC-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Sus scrofa 57739 R-SSC-6786650 https://reactome.org/PathwayBrowser/#/R-SSC-6786650 DDHD1,2 hydrolyse PA IEA Sus scrofa 57739 R-SSC-6792445 https://reactome.org/PathwayBrowser/#/R-SSC-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Sus scrofa 57739 R-SSC-6801250 https://reactome.org/PathwayBrowser/#/R-SSC-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Sus scrofa 57739 R-SSC-75885 https://reactome.org/PathwayBrowser/#/R-SSC-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Sus scrofa 57739 R-SSC-8869241 https://reactome.org/PathwayBrowser/#/R-SSC-8869241 PITPNM1,2,3 exchange PI for PA IEA Sus scrofa 57739 R-SSC-8954398 https://reactome.org/PathwayBrowser/#/R-SSC-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Sus scrofa 57739 R-XTR-1482604 https://reactome.org/PathwayBrowser/#/R-XTR-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Xenopus tropicalis 57739 R-XTR-1482656 https://reactome.org/PathwayBrowser/#/R-XTR-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Xenopus tropicalis 57739 R-XTR-1482679 https://reactome.org/PathwayBrowser/#/R-XTR-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Xenopus tropicalis 57739 R-XTR-1483121 https://reactome.org/PathwayBrowser/#/R-XTR-1483121 PA is converted to CDP-DAG by CDS1 IEA Xenopus tropicalis 57739 R-XTR-1483165 https://reactome.org/PathwayBrowser/#/R-XTR-1483165 PA is converted to CDP-DAG by CDS2 IEA Xenopus tropicalis 57739 R-XTR-1483182 https://reactome.org/PathwayBrowser/#/R-XTR-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Xenopus tropicalis 57739 R-XTR-1483203 https://reactome.org/PathwayBrowser/#/R-XTR-1483203 PA is dephosphorylated to DAG by LPIN IEA Xenopus tropicalis 57739 R-XTR-1602446 https://reactome.org/PathwayBrowser/#/R-XTR-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Xenopus tropicalis 57739 R-XTR-2029468 https://reactome.org/PathwayBrowser/#/R-XTR-2029468 Conversion of PA into DAG by PAP-1 IEA Xenopus tropicalis 57739 R-XTR-2029471 https://reactome.org/PathwayBrowser/#/R-XTR-2029471 Hydrolysis of PC to PA by PLD IEA Xenopus tropicalis 57739 R-XTR-5696074 https://reactome.org/PathwayBrowser/#/R-XTR-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Xenopus tropicalis 57739 R-XTR-6786650 https://reactome.org/PathwayBrowser/#/R-XTR-6786650 DDHD1,2 hydrolyse PA IEA Xenopus tropicalis 57739 R-XTR-6792445 https://reactome.org/PathwayBrowser/#/R-XTR-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Xenopus tropicalis 57739 R-XTR-75885 https://reactome.org/PathwayBrowser/#/R-XTR-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Xenopus tropicalis 57739 R-XTR-8954398 https://reactome.org/PathwayBrowser/#/R-XTR-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Xenopus tropicalis 57743 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 57743 R-BTA-418436 https://reactome.org/PathwayBrowser/#/R-BTA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Bos taurus 57743 R-BTA-5693373 https://reactome.org/PathwayBrowser/#/R-BTA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Bos taurus 57743 R-BTA-70560 https://reactome.org/PathwayBrowser/#/R-BTA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Bos taurus 57743 R-BTA-70577 https://reactome.org/PathwayBrowser/#/R-BTA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Bos taurus 57743 R-BTA-70634 https://reactome.org/PathwayBrowser/#/R-BTA-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Bos taurus 57743 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 57743 R-CEL-70634 https://reactome.org/PathwayBrowser/#/R-CEL-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Caenorhabditis elegans 57743 R-CFA-418436 https://reactome.org/PathwayBrowser/#/R-CFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Canis familiaris 57743 R-CFA-5693373 https://reactome.org/PathwayBrowser/#/R-CFA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Canis familiaris 57743 R-CFA-70560 https://reactome.org/PathwayBrowser/#/R-CFA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Canis familiaris 57743 R-CFA-70577 https://reactome.org/PathwayBrowser/#/R-CFA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Canis familiaris 57743 R-CFA-70634 https://reactome.org/PathwayBrowser/#/R-CFA-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Canis familiaris 57743 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 57743 R-DDI-418436 https://reactome.org/PathwayBrowser/#/R-DDI-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Dictyostelium discoideum 57743 R-DDI-70634 https://reactome.org/PathwayBrowser/#/R-DDI-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Dictyostelium discoideum 57743 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 57743 R-DME-418436 https://reactome.org/PathwayBrowser/#/R-DME-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Drosophila melanogaster 57743 R-DME-5693373 https://reactome.org/PathwayBrowser/#/R-DME-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Drosophila melanogaster 57743 R-DME-70634 https://reactome.org/PathwayBrowser/#/R-DME-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Drosophila melanogaster 57743 R-DRE-418436 https://reactome.org/PathwayBrowser/#/R-DRE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Danio rerio 57743 R-DRE-70634 https://reactome.org/PathwayBrowser/#/R-DRE-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Danio rerio 57743 R-GGA-187586 https://reactome.org/PathwayBrowser/#/R-GGA-187586 ATP + aspartate + citrulline <=> argininosuccinate + AMP + pyrophosphate TAS Gallus gallus 57743 R-GGA-187588 https://reactome.org/PathwayBrowser/#/R-GGA-187588 carbamoyl phosphate + ornithine => citrulline + orthophosphate TAS Gallus gallus 57743 R-GGA-187608 https://reactome.org/PathwayBrowser/#/R-GGA-187608 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Gallus gallus 57743 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 57743 R-GGA-418436 https://reactome.org/PathwayBrowser/#/R-GGA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Gallus gallus 57743 R-GGA-5693373 https://reactome.org/PathwayBrowser/#/R-GGA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Gallus gallus 57743 R-GGA-70560 https://reactome.org/PathwayBrowser/#/R-GGA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Gallus gallus 57743 R-GGA-70577 https://reactome.org/PathwayBrowser/#/R-GGA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Gallus gallus 57743 R-GGA-70634 https://reactome.org/PathwayBrowser/#/R-GGA-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Gallus gallus 57743 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 57743 R-HSA-418436 https://reactome.org/PathwayBrowser/#/R-HSA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) TAS Homo sapiens 57743 R-HSA-5693373 https://reactome.org/PathwayBrowser/#/R-HSA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit TAS Homo sapiens 57743 R-HSA-70560 https://reactome.org/PathwayBrowser/#/R-HSA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate TAS Homo sapiens 57743 R-HSA-70577 https://reactome.org/PathwayBrowser/#/R-HSA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA TAS Homo sapiens 57743 R-HSA-70634 https://reactome.org/PathwayBrowser/#/R-HSA-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) TAS Homo sapiens 57743 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 57743 R-MMU-418436 https://reactome.org/PathwayBrowser/#/R-MMU-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Mus musculus 57743 R-MMU-5693373 https://reactome.org/PathwayBrowser/#/R-MMU-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Mus musculus 57743 R-MMU-70560 https://reactome.org/PathwayBrowser/#/R-MMU-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Mus musculus 57743 R-MMU-70577 https://reactome.org/PathwayBrowser/#/R-MMU-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Mus musculus 57743 R-MMU-70634 https://reactome.org/PathwayBrowser/#/R-MMU-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Mus musculus 57743 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 57743 R-PFA-418436 https://reactome.org/PathwayBrowser/#/R-PFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Plasmodium falciparum 57743 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 57743 R-RNO-418436 https://reactome.org/PathwayBrowser/#/R-RNO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Rattus norvegicus 57743 R-RNO-5693373 https://reactome.org/PathwayBrowser/#/R-RNO-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Rattus norvegicus 57743 R-RNO-70560 https://reactome.org/PathwayBrowser/#/R-RNO-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Rattus norvegicus 57743 R-RNO-70634 https://reactome.org/PathwayBrowser/#/R-RNO-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Rattus norvegicus 57743 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 57743 R-SCE-418436 https://reactome.org/PathwayBrowser/#/R-SCE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Saccharomyces cerevisiae 57743 R-SCE-70560 https://reactome.org/PathwayBrowser/#/R-SCE-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Saccharomyces cerevisiae 57743 R-SCE-70634 https://reactome.org/PathwayBrowser/#/R-SCE-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Saccharomyces cerevisiae 57743 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 57743 R-SPO-418436 https://reactome.org/PathwayBrowser/#/R-SPO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Schizosaccharomyces pombe 57743 R-SPO-70560 https://reactome.org/PathwayBrowser/#/R-SPO-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Schizosaccharomyces pombe 57743 R-SPO-70634 https://reactome.org/PathwayBrowser/#/R-SPO-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Schizosaccharomyces pombe 57743 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 57743 R-SSC-418436 https://reactome.org/PathwayBrowser/#/R-SSC-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Sus scrofa 57743 R-SSC-70560 https://reactome.org/PathwayBrowser/#/R-SSC-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Sus scrofa 57743 R-SSC-70577 https://reactome.org/PathwayBrowser/#/R-SSC-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Sus scrofa 57743 R-SSC-70634 https://reactome.org/PathwayBrowser/#/R-SSC-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Sus scrofa 57743 R-XTR-5693373 https://reactome.org/PathwayBrowser/#/R-XTR-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Xenopus tropicalis 57743 R-XTR-70560 https://reactome.org/PathwayBrowser/#/R-XTR-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Xenopus tropicalis 57743 R-XTR-70634 https://reactome.org/PathwayBrowser/#/R-XTR-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Xenopus tropicalis 57756 R-BTA-428690 https://reactome.org/PathwayBrowser/#/R-BTA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Bos taurus 57756 R-BTA-428696 https://reactome.org/PathwayBrowser/#/R-BTA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Bos taurus 57756 R-CEL-428690 https://reactome.org/PathwayBrowser/#/R-CEL-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Caenorhabditis elegans 57756 R-CEL-428696 https://reactome.org/PathwayBrowser/#/R-CEL-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Caenorhabditis elegans 57756 R-CFA-428690 https://reactome.org/PathwayBrowser/#/R-CFA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Canis familiaris 57756 R-CFA-428696 https://reactome.org/PathwayBrowser/#/R-CFA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Canis familiaris 57756 R-DDI-428690 https://reactome.org/PathwayBrowser/#/R-DDI-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Dictyostelium discoideum 57756 R-DDI-428696 https://reactome.org/PathwayBrowser/#/R-DDI-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Dictyostelium discoideum 57756 R-DME-428690 https://reactome.org/PathwayBrowser/#/R-DME-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Drosophila melanogaster 57756 R-DME-428696 https://reactome.org/PathwayBrowser/#/R-DME-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Drosophila melanogaster 57756 R-DRE-428696 https://reactome.org/PathwayBrowser/#/R-DRE-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Danio rerio 57756 R-GGA-428690 https://reactome.org/PathwayBrowser/#/R-GGA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Gallus gallus 57756 R-GGA-428696 https://reactome.org/PathwayBrowser/#/R-GGA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Gallus gallus 57756 R-HSA-428690 https://reactome.org/PathwayBrowser/#/R-HSA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate TAS Homo sapiens 57756 R-HSA-428696 https://reactome.org/PathwayBrowser/#/R-HSA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate TAS Homo sapiens 57756 R-MMU-428690 https://reactome.org/PathwayBrowser/#/R-MMU-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Mus musculus 57756 R-MMU-428696 https://reactome.org/PathwayBrowser/#/R-MMU-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Mus musculus 57756 R-RNO-428690 https://reactome.org/PathwayBrowser/#/R-RNO-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Rattus norvegicus 57756 R-RNO-428696 https://reactome.org/PathwayBrowser/#/R-RNO-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Rattus norvegicus 57756 R-SCE-428690 https://reactome.org/PathwayBrowser/#/R-SCE-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Saccharomyces cerevisiae 57756 R-SCE-428696 https://reactome.org/PathwayBrowser/#/R-SCE-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Saccharomyces cerevisiae 57756 R-SPO-428690 https://reactome.org/PathwayBrowser/#/R-SPO-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Schizosaccharomyces pombe 57756 R-SPO-428696 https://reactome.org/PathwayBrowser/#/R-SPO-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Schizosaccharomyces pombe 57756 R-SSC-428690 https://reactome.org/PathwayBrowser/#/R-SSC-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Sus scrofa 57756 R-SSC-428696 https://reactome.org/PathwayBrowser/#/R-SSC-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Sus scrofa 57756 R-XTR-428696 https://reactome.org/PathwayBrowser/#/R-XTR-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Xenopus tropicalis 57762 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 57762 R-BTA-352103 https://reactome.org/PathwayBrowser/#/R-BTA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Bos taurus 57762 R-BTA-352107 https://reactome.org/PathwayBrowser/#/R-BTA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Bos taurus 57762 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 57762 R-BTA-352232 https://reactome.org/PathwayBrowser/#/R-BTA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Bos taurus 57762 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 57762 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 57762 R-BTA-508179 https://reactome.org/PathwayBrowser/#/R-BTA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Bos taurus 57762 R-BTA-508189 https://reactome.org/PathwayBrowser/#/R-BTA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Bos taurus 57762 R-BTA-6784959 https://reactome.org/PathwayBrowser/#/R-BTA-6784959 BPHL hydrolyses VACV to ACV IEA Bos taurus 57762 R-BTA-70723 https://reactome.org/PathwayBrowser/#/R-BTA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Bos taurus 57762 R-BTA-70724 https://reactome.org/PathwayBrowser/#/R-BTA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Bos taurus 57762 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 57762 R-CEL-508179 https://reactome.org/PathwayBrowser/#/R-CEL-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Caenorhabditis elegans 57762 R-CEL-508189 https://reactome.org/PathwayBrowser/#/R-CEL-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Caenorhabditis elegans 57762 R-CEL-6784959 https://reactome.org/PathwayBrowser/#/R-CEL-6784959 BPHL hydrolyses VACV to ACV IEA Caenorhabditis elegans 57762 R-CEL-70723 https://reactome.org/PathwayBrowser/#/R-CEL-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Caenorhabditis elegans 57762 R-CEL-70724 https://reactome.org/PathwayBrowser/#/R-CEL-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Caenorhabditis elegans 57762 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 57762 R-CFA-352103 https://reactome.org/PathwayBrowser/#/R-CFA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Canis familiaris 57762 R-CFA-352107 https://reactome.org/PathwayBrowser/#/R-CFA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Canis familiaris 57762 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 57762 R-CFA-352232 https://reactome.org/PathwayBrowser/#/R-CFA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Canis familiaris 57762 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 57762 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 57762 R-CFA-508179 https://reactome.org/PathwayBrowser/#/R-CFA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Canis familiaris 57762 R-CFA-508189 https://reactome.org/PathwayBrowser/#/R-CFA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Canis familiaris 57762 R-CFA-6784959 https://reactome.org/PathwayBrowser/#/R-CFA-6784959 BPHL hydrolyses VACV to ACV IEA Canis familiaris 57762 R-CFA-70723 https://reactome.org/PathwayBrowser/#/R-CFA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Canis familiaris 57762 R-CFA-70724 https://reactome.org/PathwayBrowser/#/R-CFA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Canis familiaris 57762 R-DDI-508179 https://reactome.org/PathwayBrowser/#/R-DDI-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Dictyostelium discoideum 57762 R-DDI-508189 https://reactome.org/PathwayBrowser/#/R-DDI-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Dictyostelium discoideum 57762 R-DDI-70723 https://reactome.org/PathwayBrowser/#/R-DDI-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Dictyostelium discoideum 57762 R-DDI-70724 https://reactome.org/PathwayBrowser/#/R-DDI-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Dictyostelium discoideum 57762 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 57762 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57762 R-DME-352232 https://reactome.org/PathwayBrowser/#/R-DME-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Drosophila melanogaster 57762 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57762 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57762 R-DME-508179 https://reactome.org/PathwayBrowser/#/R-DME-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Drosophila melanogaster 57762 R-DME-508189 https://reactome.org/PathwayBrowser/#/R-DME-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Drosophila melanogaster 57762 R-DME-6784959 https://reactome.org/PathwayBrowser/#/R-DME-6784959 BPHL hydrolyses VACV to ACV IEA Drosophila melanogaster 57762 R-DME-70723 https://reactome.org/PathwayBrowser/#/R-DME-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Drosophila melanogaster 57762 R-DME-70724 https://reactome.org/PathwayBrowser/#/R-DME-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Drosophila melanogaster 57762 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 57762 R-DRE-352103 https://reactome.org/PathwayBrowser/#/R-DRE-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Danio rerio 57762 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 57762 R-DRE-508179 https://reactome.org/PathwayBrowser/#/R-DRE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Danio rerio 57762 R-DRE-508189 https://reactome.org/PathwayBrowser/#/R-DRE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Danio rerio 57762 R-DRE-70723 https://reactome.org/PathwayBrowser/#/R-DRE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Danio rerio 57762 R-DRE-70724 https://reactome.org/PathwayBrowser/#/R-DRE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Danio rerio 57762 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 57762 R-GGA-352107 https://reactome.org/PathwayBrowser/#/R-GGA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Gallus gallus 57762 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 57762 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 57762 R-GGA-508189 https://reactome.org/PathwayBrowser/#/R-GGA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Gallus gallus 57762 R-GGA-6784959 https://reactome.org/PathwayBrowser/#/R-GGA-6784959 BPHL hydrolyses VACV to ACV IEA Gallus gallus 57762 R-GGA-70723 https://reactome.org/PathwayBrowser/#/R-GGA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Gallus gallus 57762 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 57762 R-HSA-352103 https://reactome.org/PathwayBrowser/#/R-HSA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids TAS Homo sapiens 57762 R-HSA-352107 https://reactome.org/PathwayBrowser/#/R-HSA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids TAS Homo sapiens 57762 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 57762 R-HSA-352232 https://reactome.org/PathwayBrowser/#/R-HSA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol TAS Homo sapiens 57762 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57762 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57762 R-HSA-380042 https://reactome.org/PathwayBrowser/#/R-HSA-380042 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate TAS Homo sapiens 57762 R-HSA-380199 https://reactome.org/PathwayBrowser/#/R-HSA-380199 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate IEA Homo sapiens 57762 R-HSA-508179 https://reactome.org/PathwayBrowser/#/R-HSA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] TAS Homo sapiens 57762 R-HSA-508189 https://reactome.org/PathwayBrowser/#/R-HSA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] TAS Homo sapiens 57762 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57762 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57762 R-HSA-6784959 https://reactome.org/PathwayBrowser/#/R-HSA-6784959 BPHL hydrolyses VACV to ACV TAS Homo sapiens 57762 R-HSA-70723 https://reactome.org/PathwayBrowser/#/R-HSA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] TAS Homo sapiens 57762 R-HSA-70724 https://reactome.org/PathwayBrowser/#/R-HSA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] TAS Homo sapiens 57762 R-HSA-9672770 https://reactome.org/PathwayBrowser/#/R-HSA-9672770 SLC25A44 transports Leu, Ile and Val from cytosol to mitochondrial matrix IEA Homo sapiens 57762 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 57762 R-MMU-352103 https://reactome.org/PathwayBrowser/#/R-MMU-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Mus musculus 57762 R-MMU-352107 https://reactome.org/PathwayBrowser/#/R-MMU-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Mus musculus 57762 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 57762 R-MMU-352232 https://reactome.org/PathwayBrowser/#/R-MMU-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Mus musculus 57762 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 57762 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 57762 R-MMU-508179 https://reactome.org/PathwayBrowser/#/R-MMU-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Mus musculus 57762 R-MMU-508189 https://reactome.org/PathwayBrowser/#/R-MMU-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Mus musculus 57762 R-MMU-6784959 https://reactome.org/PathwayBrowser/#/R-MMU-6784959 BPHL hydrolyses VACV to ACV IEA Mus musculus 57762 R-MMU-70723 https://reactome.org/PathwayBrowser/#/R-MMU-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Mus musculus 57762 R-MMU-70724 https://reactome.org/PathwayBrowser/#/R-MMU-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Mus musculus 57762 R-MMU-9673827 https://reactome.org/PathwayBrowser/#/R-MMU-9673827 Slc25a44 transports Leu, Ile and Val from cytosol to mitochondrial matrix TAS Mus musculus 57762 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 57762 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57762 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57762 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 57762 R-RNO-352103 https://reactome.org/PathwayBrowser/#/R-RNO-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Rattus norvegicus 57762 R-RNO-352107 https://reactome.org/PathwayBrowser/#/R-RNO-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Rattus norvegicus 57762 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 57762 R-RNO-352232 https://reactome.org/PathwayBrowser/#/R-RNO-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Rattus norvegicus 57762 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 57762 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 57762 R-RNO-508179 https://reactome.org/PathwayBrowser/#/R-RNO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Rattus norvegicus 57762 R-RNO-508189 https://reactome.org/PathwayBrowser/#/R-RNO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Rattus norvegicus 57762 R-RNO-6784959 https://reactome.org/PathwayBrowser/#/R-RNO-6784959 BPHL hydrolyses VACV to ACV IEA Rattus norvegicus 57762 R-RNO-70723 https://reactome.org/PathwayBrowser/#/R-RNO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Rattus norvegicus 57762 R-RNO-70724 https://reactome.org/PathwayBrowser/#/R-RNO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Rattus norvegicus 57762 R-SCE-508179 https://reactome.org/PathwayBrowser/#/R-SCE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Saccharomyces cerevisiae 57762 R-SCE-508189 https://reactome.org/PathwayBrowser/#/R-SCE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Saccharomyces cerevisiae 57762 R-SCE-70723 https://reactome.org/PathwayBrowser/#/R-SCE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Saccharomyces cerevisiae 57762 R-SCE-70724 https://reactome.org/PathwayBrowser/#/R-SCE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Saccharomyces cerevisiae 57762 R-SPO-508179 https://reactome.org/PathwayBrowser/#/R-SPO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Schizosaccharomyces pombe 57762 R-SPO-508189 https://reactome.org/PathwayBrowser/#/R-SPO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Schizosaccharomyces pombe 57762 R-SPO-70723 https://reactome.org/PathwayBrowser/#/R-SPO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Schizosaccharomyces pombe 57762 R-SPO-70724 https://reactome.org/PathwayBrowser/#/R-SPO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Schizosaccharomyces pombe 57762 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 57762 R-SSC-352103 https://reactome.org/PathwayBrowser/#/R-SSC-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Sus scrofa 57762 R-SSC-352107 https://reactome.org/PathwayBrowser/#/R-SSC-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Sus scrofa 57762 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 57762 R-SSC-352232 https://reactome.org/PathwayBrowser/#/R-SSC-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Sus scrofa 57762 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 57762 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 57762 R-SSC-508179 https://reactome.org/PathwayBrowser/#/R-SSC-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Sus scrofa 57762 R-SSC-508189 https://reactome.org/PathwayBrowser/#/R-SSC-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Sus scrofa 57762 R-SSC-6784959 https://reactome.org/PathwayBrowser/#/R-SSC-6784959 BPHL hydrolyses VACV to ACV IEA Sus scrofa 57762 R-SSC-70723 https://reactome.org/PathwayBrowser/#/R-SSC-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Sus scrofa 57762 R-SSC-70724 https://reactome.org/PathwayBrowser/#/R-SSC-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Sus scrofa 57762 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 57762 R-XTR-352103 https://reactome.org/PathwayBrowser/#/R-XTR-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Xenopus tropicalis 57762 R-XTR-352107 https://reactome.org/PathwayBrowser/#/R-XTR-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Xenopus tropicalis 57762 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57762 R-XTR-352232 https://reactome.org/PathwayBrowser/#/R-XTR-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Xenopus tropicalis 57762 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57762 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57762 R-XTR-508179 https://reactome.org/PathwayBrowser/#/R-XTR-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Xenopus tropicalis 57762 R-XTR-508189 https://reactome.org/PathwayBrowser/#/R-XTR-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Xenopus tropicalis 57762 R-XTR-70723 https://reactome.org/PathwayBrowser/#/R-XTR-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Xenopus tropicalis 57762 R-XTR-70724 https://reactome.org/PathwayBrowser/#/R-XTR-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Xenopus tropicalis 57776 R-BTA-446185 https://reactome.org/PathwayBrowser/#/R-BTA-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Bos taurus 57776 R-BTA-446204 https://reactome.org/PathwayBrowser/#/R-BTA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Bos taurus 57776 R-CEL-446185 https://reactome.org/PathwayBrowser/#/R-CEL-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Caenorhabditis elegans 57776 R-CEL-446204 https://reactome.org/PathwayBrowser/#/R-CEL-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Caenorhabditis elegans 57776 R-CFA-446185 https://reactome.org/PathwayBrowser/#/R-CFA-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Canis familiaris 57776 R-CFA-446204 https://reactome.org/PathwayBrowser/#/R-CFA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Canis familiaris 57776 R-DDI-446204 https://reactome.org/PathwayBrowser/#/R-DDI-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Dictyostelium discoideum 57776 R-DME-446185 https://reactome.org/PathwayBrowser/#/R-DME-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Drosophila melanogaster 57776 R-DME-446204 https://reactome.org/PathwayBrowser/#/R-DME-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Drosophila melanogaster 57776 R-DRE-446204 https://reactome.org/PathwayBrowser/#/R-DRE-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Danio rerio 57776 R-GGA-446185 https://reactome.org/PathwayBrowser/#/R-GGA-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Gallus gallus 57776 R-GGA-446204 https://reactome.org/PathwayBrowser/#/R-GGA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Gallus gallus 57776 R-HSA-446185 https://reactome.org/PathwayBrowser/#/R-HSA-446185 Isomerization of GlcNAc6P to GlcNAc1P TAS Homo sapiens 57776 R-HSA-446204 https://reactome.org/PathwayBrowser/#/R-HSA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine TAS Homo sapiens 57776 R-MMU-446185 https://reactome.org/PathwayBrowser/#/R-MMU-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Mus musculus 57776 R-MMU-446204 https://reactome.org/PathwayBrowser/#/R-MMU-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Mus musculus 57776 R-PFA-446185 https://reactome.org/PathwayBrowser/#/R-PFA-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Plasmodium falciparum 57776 R-PFA-446204 https://reactome.org/PathwayBrowser/#/R-PFA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Plasmodium falciparum 57776 R-RNO-446185 https://reactome.org/PathwayBrowser/#/R-RNO-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Rattus norvegicus 57776 R-RNO-446204 https://reactome.org/PathwayBrowser/#/R-RNO-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Rattus norvegicus 57776 R-SCE-446185 https://reactome.org/PathwayBrowser/#/R-SCE-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Saccharomyces cerevisiae 57776 R-SCE-446204 https://reactome.org/PathwayBrowser/#/R-SCE-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Saccharomyces cerevisiae 57776 R-SPO-446185 https://reactome.org/PathwayBrowser/#/R-SPO-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Schizosaccharomyces pombe 57776 R-SPO-446204 https://reactome.org/PathwayBrowser/#/R-SPO-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Schizosaccharomyces pombe 57776 R-SSC-446185 https://reactome.org/PathwayBrowser/#/R-SSC-446185 Isomerization of GlcNAc6P to GlcNAc1P IEA Sus scrofa 57776 R-SSC-446204 https://reactome.org/PathwayBrowser/#/R-SSC-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Sus scrofa 57776 R-XTR-446204 https://reactome.org/PathwayBrowser/#/R-XTR-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Xenopus tropicalis 57783 R-BTA-1222376 https://reactome.org/PathwayBrowser/#/R-BTA-1222376 NOX2 generates superoxide from oxygen IEA Bos taurus 57783 R-BTA-1475414 https://reactome.org/PathwayBrowser/#/R-BTA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Bos taurus 57783 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 57783 R-BTA-1497869 https://reactome.org/PathwayBrowser/#/R-BTA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Bos taurus 57783 R-BTA-156526 https://reactome.org/PathwayBrowser/#/R-BTA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Bos taurus 57783 R-BTA-1655453 https://reactome.org/PathwayBrowser/#/R-BTA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Bos taurus 57783 R-BTA-189384 https://reactome.org/PathwayBrowser/#/R-BTA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Bos taurus 57783 R-BTA-189398 https://reactome.org/PathwayBrowser/#/R-BTA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Bos taurus 57783 R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 57783 R-BTA-191352 https://reactome.org/PathwayBrowser/#/R-BTA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Bos taurus 57783 R-BTA-191402 https://reactome.org/PathwayBrowser/#/R-BTA-191402 Reduction of presqualene diphosphate to form squalene IEA Bos taurus 57783 R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 57783 R-BTA-191999 https://reactome.org/PathwayBrowser/#/R-BTA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Bos taurus 57783 R-BTA-192033 https://reactome.org/PathwayBrowser/#/R-BTA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Bos taurus 57783 R-BTA-192036 https://reactome.org/PathwayBrowser/#/R-BTA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Bos taurus 57783 R-BTA-192042 https://reactome.org/PathwayBrowser/#/R-BTA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 57783 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 57783 R-BTA-192054 https://reactome.org/PathwayBrowser/#/R-BTA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Bos taurus 57783 R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 57783 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 57783 R-BTA-192067 https://reactome.org/PathwayBrowser/#/R-BTA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Bos taurus 57783 R-BTA-192123 https://reactome.org/PathwayBrowser/#/R-BTA-192123 CYP27A1 27-hydroxylates CHOL IEA Bos taurus 57783 R-BTA-192160 https://reactome.org/PathwayBrowser/#/R-BTA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Bos taurus 57783 R-BTA-192178 https://reactome.org/PathwayBrowser/#/R-BTA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Bos taurus 57783 R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 57783 R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 57783 R-BTA-193064 https://reactome.org/PathwayBrowser/#/R-BTA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Bos taurus 57783 R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 57783 R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 57783 R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 57783 R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 57783 R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 57783 R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 57783 R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 57783 R-BTA-193393 https://reactome.org/PathwayBrowser/#/R-BTA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Bos taurus 57783 R-BTA-193460 https://reactome.org/PathwayBrowser/#/R-BTA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Bos taurus 57783 R-BTA-193497 https://reactome.org/PathwayBrowser/#/R-BTA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Bos taurus 57783 R-BTA-193713 https://reactome.org/PathwayBrowser/#/R-BTA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Bos taurus 57783 R-BTA-193719 https://reactome.org/PathwayBrowser/#/R-BTA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 57783 R-BTA-193737 https://reactome.org/PathwayBrowser/#/R-BTA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Bos taurus 57783 R-BTA-193746 https://reactome.org/PathwayBrowser/#/R-BTA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Bos taurus 57783 R-BTA-193755 https://reactome.org/PathwayBrowser/#/R-BTA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Bos taurus 57783 R-BTA-193758 https://reactome.org/PathwayBrowser/#/R-BTA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Bos taurus 57783 R-BTA-193780 https://reactome.org/PathwayBrowser/#/R-BTA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Bos taurus 57783 R-BTA-193781 https://reactome.org/PathwayBrowser/#/R-BTA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Bos taurus 57783 R-BTA-193787 https://reactome.org/PathwayBrowser/#/R-BTA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Bos taurus 57783 R-BTA-193792 https://reactome.org/PathwayBrowser/#/R-BTA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Bos taurus 57783 R-BTA-193800 https://reactome.org/PathwayBrowser/#/R-BTA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Bos taurus 57783 R-BTA-193821 https://reactome.org/PathwayBrowser/#/R-BTA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Bos taurus 57783 R-BTA-193824 https://reactome.org/PathwayBrowser/#/R-BTA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Bos taurus 57783 R-BTA-193841 https://reactome.org/PathwayBrowser/#/R-BTA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Bos taurus 57783 R-BTA-193964 https://reactome.org/PathwayBrowser/#/R-BTA-193964 CYP21A2 21-hydroxylates PROG IEA Bos taurus 57783 R-BTA-193965 https://reactome.org/PathwayBrowser/#/R-BTA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Bos taurus 57783 R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 57783 R-BTA-193995 https://reactome.org/PathwayBrowser/#/R-BTA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Bos taurus 57783 R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 57783 R-BTA-194017 https://reactome.org/PathwayBrowser/#/R-BTA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Bos taurus 57783 R-BTA-194023 https://reactome.org/PathwayBrowser/#/R-BTA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Bos taurus 57783 R-BTA-194632 https://reactome.org/PathwayBrowser/#/R-BTA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Bos taurus 57783 R-BTA-194641 https://reactome.org/PathwayBrowser/#/R-BTA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 57783 R-BTA-194669 https://reactome.org/PathwayBrowser/#/R-BTA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 57783 R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 57783 R-BTA-194689 https://reactome.org/PathwayBrowser/#/R-BTA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Bos taurus 57783 R-BTA-194698 https://reactome.org/PathwayBrowser/#/R-BTA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Bos taurus 57783 R-BTA-195664 https://reactome.org/PathwayBrowser/#/R-BTA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Bos taurus 57783 R-BTA-196060 https://reactome.org/PathwayBrowser/#/R-BTA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Bos taurus 57783 R-BTA-196402 https://reactome.org/PathwayBrowser/#/R-BTA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Bos taurus 57783 R-BTA-196417 https://reactome.org/PathwayBrowser/#/R-BTA-196417 Reduction of desmosterol to cholesterol IEA Bos taurus 57783 R-BTA-197963 https://reactome.org/PathwayBrowser/#/R-BTA-197963 DHFR2 reduces FOLA to DHF IEA Bos taurus 57783 R-BTA-197972 https://reactome.org/PathwayBrowser/#/R-BTA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Bos taurus 57783 R-BTA-200644 https://reactome.org/PathwayBrowser/#/R-BTA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Bos taurus 57783 R-BTA-200676 https://reactome.org/PathwayBrowser/#/R-BTA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Bos taurus 57783 R-BTA-200718 https://reactome.org/PathwayBrowser/#/R-BTA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Bos taurus 57783 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 57783 R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 57783 R-BTA-209772 https://reactome.org/PathwayBrowser/#/R-BTA-209772 Thyroxine is deiodinated to triiodothyronine IEA Bos taurus 57783 R-BTA-209845 https://reactome.org/PathwayBrowser/#/R-BTA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Bos taurus 57783 R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 57783 R-BTA-211873 https://reactome.org/PathwayBrowser/#/R-BTA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Bos taurus 57783 R-BTA-211923 https://reactome.org/PathwayBrowser/#/R-BTA-211923 CYP26C1 4-hydroxylates 9cRA IEA Bos taurus 57783 R-BTA-211950 https://reactome.org/PathwayBrowser/#/R-BTA-211950 CYP24A1 24-hydroxylates CTL IEA Bos taurus 57783 R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 57783 R-BTA-2161549 https://reactome.org/PathwayBrowser/#/R-BTA-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Bos taurus 57783 R-BTA-2161614 https://reactome.org/PathwayBrowser/#/R-BTA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Bos taurus 57783 R-BTA-2161651 https://reactome.org/PathwayBrowser/#/R-BTA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Bos taurus 57783 R-BTA-2161745 https://reactome.org/PathwayBrowser/#/R-BTA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Bos taurus 57783 R-BTA-2161792 https://reactome.org/PathwayBrowser/#/R-BTA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Bos taurus 57783 R-BTA-2161890 https://reactome.org/PathwayBrowser/#/R-BTA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Bos taurus 57783 R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Bos taurus 57783 R-BTA-2161951 https://reactome.org/PathwayBrowser/#/R-BTA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Bos taurus 57783 R-BTA-2395517 https://reactome.org/PathwayBrowser/#/R-BTA-2395517 NADPH transfers electrons to FDXR IEA Bos taurus 57783 R-BTA-2408527 https://reactome.org/PathwayBrowser/#/R-BTA-2408527 SeO3(2-) is reduced to H2Se by TXNRD1 TAS Bos taurus 57783 R-BTA-2464776 https://reactome.org/PathwayBrowser/#/R-BTA-2464776 Rdh8 reduces atRAL to atROL TAS Bos taurus 57783 R-BTA-2464822 https://reactome.org/PathwayBrowser/#/R-BTA-2464822 RDH12 reduces atRAL to atROL IEA Bos taurus 57783 R-BTA-2465940 https://reactome.org/PathwayBrowser/#/R-BTA-2465940 atRAL is reduced to atROL IEA Bos taurus 57783 R-BTA-2855252 https://reactome.org/PathwayBrowser/#/R-BTA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Bos taurus 57783 R-BTA-3149518 https://reactome.org/PathwayBrowser/#/R-BTA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Bos taurus 57783 R-BTA-3149519 https://reactome.org/PathwayBrowser/#/R-BTA-3149519 MMACHC decyanates CNCbl IEA Bos taurus 57783 R-BTA-3323050 https://reactome.org/PathwayBrowser/#/R-BTA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Bos taurus 57783 R-BTA-3323079 https://reactome.org/PathwayBrowser/#/R-BTA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 57783 R-BTA-350869 https://reactome.org/PathwayBrowser/#/R-BTA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Bos taurus 57783 R-BTA-389540 https://reactome.org/PathwayBrowser/#/R-BTA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 57783 R-BTA-390425 https://reactome.org/PathwayBrowser/#/R-BTA-390425 FAR1 reduces PalmCoA to HXOL IEA Bos taurus 57783 R-BTA-390438 https://reactome.org/PathwayBrowser/#/R-BTA-390438 FAR2 reduces PalmCoA to HXOL IEA Bos taurus 57783 R-BTA-418436 https://reactome.org/PathwayBrowser/#/R-BTA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Bos taurus 57783 R-BTA-428123 https://reactome.org/PathwayBrowser/#/R-BTA-428123 KDSR reduces 3-ketosphingoid IEA Bos taurus 57783 R-BTA-4419979 https://reactome.org/PathwayBrowser/#/R-BTA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Bos taurus 57783 R-BTA-450971 https://reactome.org/PathwayBrowser/#/R-BTA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Bos taurus 57783 R-BTA-450984 https://reactome.org/PathwayBrowser/#/R-BTA-450984 IDH2 dimer decarboxylates isocitrate IEA Bos taurus 57783 R-BTA-469659 https://reactome.org/PathwayBrowser/#/R-BTA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Bos taurus 57783 R-BTA-508040 https://reactome.org/PathwayBrowser/#/R-BTA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Bos taurus 57783 R-BTA-514604 https://reactome.org/PathwayBrowser/#/R-BTA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Bos taurus 57783 R-BTA-5218841 https://reactome.org/PathwayBrowser/#/R-BTA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Bos taurus 57783 R-BTA-5263614 https://reactome.org/PathwayBrowser/#/R-BTA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Bos taurus 57783 R-BTA-5263616 https://reactome.org/PathwayBrowser/#/R-BTA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Bos taurus 57783 R-BTA-5340226 https://reactome.org/PathwayBrowser/#/R-BTA-5340226 CYGB dioxygenates NO IEA Bos taurus 57783 R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 57783 R-BTA-5419165 https://reactome.org/PathwayBrowser/#/R-BTA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Bos taurus 57783 R-BTA-5423637 https://reactome.org/PathwayBrowser/#/R-BTA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Bos taurus 57783 R-BTA-5423647 https://reactome.org/PathwayBrowser/#/R-BTA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Bos taurus 57783 R-BTA-5423664 https://reactome.org/PathwayBrowser/#/R-BTA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Bos taurus 57783 R-BTA-5423672 https://reactome.org/PathwayBrowser/#/R-BTA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Bos taurus 57783 R-BTA-5423678 https://reactome.org/PathwayBrowser/#/R-BTA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Bos taurus 57783 R-BTA-548818 https://reactome.org/PathwayBrowser/#/R-BTA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Bos taurus 57783 R-BTA-548831 https://reactome.org/PathwayBrowser/#/R-BTA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Bos taurus 57783 R-BTA-5602295 https://reactome.org/PathwayBrowser/#/R-BTA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Bos taurus 57783 R-BTA-5615668 https://reactome.org/PathwayBrowser/#/R-BTA-5615668 AKR1C3 reduces atRAL to atROL IEA Bos taurus 57783 R-BTA-5652172 https://reactome.org/PathwayBrowser/#/R-BTA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Bos taurus 57783 R-BTA-5661240 https://reactome.org/PathwayBrowser/#/R-BTA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Bos taurus 57783 R-BTA-5661256 https://reactome.org/PathwayBrowser/#/R-BTA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Bos taurus 57783 R-BTA-5668629 https://reactome.org/PathwayBrowser/#/R-BTA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Bos taurus 57783 R-BTA-5668718 https://reactome.org/PathwayBrowser/#/R-BTA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 57783 R-BTA-5668731 https://reactome.org/PathwayBrowser/#/R-BTA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 57783 R-BTA-5692232 https://reactome.org/PathwayBrowser/#/R-BTA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Bos taurus 57783 R-BTA-5692283 https://reactome.org/PathwayBrowser/#/R-BTA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Bos taurus 57783 R-BTA-5693390 https://reactome.org/PathwayBrowser/#/R-BTA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Bos taurus 57783 R-BTA-5696822 https://reactome.org/PathwayBrowser/#/R-BTA-5696822 AKR1B15 reduces EST17b to E1 IEA Bos taurus 57783 R-BTA-6783955 https://reactome.org/PathwayBrowser/#/R-BTA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 57783 R-BTA-6786239 https://reactome.org/PathwayBrowser/#/R-BTA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Bos taurus 57783 R-BTA-6787642 https://reactome.org/PathwayBrowser/#/R-BTA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Bos taurus 57783 R-BTA-6789092 https://reactome.org/PathwayBrowser/#/R-BTA-6789092 NOX2 generates superoxide anion from oxygen IEA Bos taurus 57783 R-BTA-6799722 https://reactome.org/PathwayBrowser/#/R-BTA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Bos taurus 57783 R-BTA-6806967 https://reactome.org/PathwayBrowser/#/R-BTA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Bos taurus 57783 R-BTA-6807053 https://reactome.org/PathwayBrowser/#/R-BTA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Bos taurus 57783 R-BTA-6807055 https://reactome.org/PathwayBrowser/#/R-BTA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Bos taurus 57783 R-BTA-6807064 https://reactome.org/PathwayBrowser/#/R-BTA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Bos taurus 57783 R-BTA-6807557 https://reactome.org/PathwayBrowser/#/R-BTA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Bos taurus 57783 R-BTA-6808487 https://reactome.org/PathwayBrowser/#/R-BTA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 57783 R-BTA-6808496 https://reactome.org/PathwayBrowser/#/R-BTA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 57783 R-BTA-6810594 https://reactome.org/PathwayBrowser/#/R-BTA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 57783 R-BTA-70377 https://reactome.org/PathwayBrowser/#/R-BTA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Bos taurus 57783 R-BTA-70577 https://reactome.org/PathwayBrowser/#/R-BTA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Bos taurus 57783 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Bos taurus 57783 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Bos taurus 57783 R-BTA-70938 https://reactome.org/PathwayBrowser/#/R-BTA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Bos taurus 57783 R-BTA-71200 https://reactome.org/PathwayBrowser/#/R-BTA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Bos taurus 57783 R-BTA-71299 https://reactome.org/PathwayBrowser/#/R-BTA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Bos taurus 57783 R-BTA-71682 https://reactome.org/PathwayBrowser/#/R-BTA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 57783 R-BTA-73585 https://reactome.org/PathwayBrowser/#/R-BTA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Bos taurus 57783 R-BTA-73616 https://reactome.org/PathwayBrowser/#/R-BTA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Bos taurus 57783 R-BTA-73646 https://reactome.org/PathwayBrowser/#/R-BTA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Bos taurus 57783 R-BTA-74872 https://reactome.org/PathwayBrowser/#/R-BTA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Bos taurus 57783 R-BTA-75872 https://reactome.org/PathwayBrowser/#/R-BTA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Bos taurus 57783 R-BTA-75883 https://reactome.org/PathwayBrowser/#/R-BTA-75883 DHRS7B reduces GO3P to HXDG3P IEA Bos taurus 57783 R-BTA-804969 https://reactome.org/PathwayBrowser/#/R-BTA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Bos taurus 57783 R-BTA-8862137 https://reactome.org/PathwayBrowser/#/R-BTA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 57783 R-BTA-8862152 https://reactome.org/PathwayBrowser/#/R-BTA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Bos taurus 57783 R-BTA-8937419 https://reactome.org/PathwayBrowser/#/R-BTA-8937419 CBR3 reduces DOX to DOXOL IEA Bos taurus 57783 R-BTA-8952873 https://reactome.org/PathwayBrowser/#/R-BTA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Bos taurus 57783 R-BTA-9012036 https://reactome.org/PathwayBrowser/#/R-BTA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Bos taurus 57783 R-BTA-9012349 https://reactome.org/PathwayBrowser/#/R-BTA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Bos taurus 57783 R-BTA-9020255 https://reactome.org/PathwayBrowser/#/R-BTA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Bos taurus 57783 R-BTA-9020256 https://reactome.org/PathwayBrowser/#/R-BTA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Bos taurus 57783 R-BTA-9020262 https://reactome.org/PathwayBrowser/#/R-BTA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Bos taurus 57783 R-BTA-9020277 https://reactome.org/PathwayBrowser/#/R-BTA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Bos taurus 57783 R-BTA-9020278 https://reactome.org/PathwayBrowser/#/R-BTA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Bos taurus 57783 R-BTA-9024881 https://reactome.org/PathwayBrowser/#/R-BTA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Bos taurus 57783 R-BTA-9024983 https://reactome.org/PathwayBrowser/#/R-BTA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Bos taurus 57783 R-BTA-9025995 https://reactome.org/PathwayBrowser/#/R-BTA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Bos taurus 57783 R-BTA-9025999 https://reactome.org/PathwayBrowser/#/R-BTA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Bos taurus 57783 R-BTA-9026007 https://reactome.org/PathwayBrowser/#/R-BTA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Bos taurus 57783 R-BTA-9027043 https://reactome.org/PathwayBrowser/#/R-BTA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Bos taurus 57783 R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 57783 R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 57783 R-BTA-9037761 https://reactome.org/PathwayBrowser/#/R-BTA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Bos taurus 57783 R-BTA-917811 https://reactome.org/PathwayBrowser/#/R-BTA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Bos taurus 57783 R-BTA-9705713 https://reactome.org/PathwayBrowser/#/R-BTA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Bos taurus 57783 R-BTA-9705714 https://reactome.org/PathwayBrowser/#/R-BTA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Bos taurus 57783 R-BTA-9709098 https://reactome.org/PathwayBrowser/#/R-BTA-9709098 DHFR dimer reduces FOLA to DHF IEA Bos taurus 57783 R-BTA-9753285 https://reactome.org/PathwayBrowser/#/R-BTA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Bos taurus 57783 R-BTA-9755937 https://reactome.org/PathwayBrowser/#/R-BTA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Bos taurus 57783 R-BTA-9756138 https://reactome.org/PathwayBrowser/#/R-BTA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Bos taurus 57783 R-BTA-9756162 https://reactome.org/PathwayBrowser/#/R-BTA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Bos taurus 57783 R-BTA-9756169 https://reactome.org/PathwayBrowser/#/R-BTA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Bos taurus 57783 R-BTA-9756180 https://reactome.org/PathwayBrowser/#/R-BTA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Bos taurus 57783 R-BTA-975629 https://reactome.org/PathwayBrowser/#/R-BTA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Bos taurus 57783 R-BTA-9758682 https://reactome.org/PathwayBrowser/#/R-BTA-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Bos taurus 57783 R-BTA-9759259 https://reactome.org/PathwayBrowser/#/R-BTA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Bos taurus 57783 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 57783 R-CEL-156526 https://reactome.org/PathwayBrowser/#/R-CEL-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Caenorhabditis elegans 57783 R-CEL-1655453 https://reactome.org/PathwayBrowser/#/R-CEL-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Caenorhabditis elegans 57783 R-CEL-191352 https://reactome.org/PathwayBrowser/#/R-CEL-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Caenorhabditis elegans 57783 R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 57783 R-CEL-192033 https://reactome.org/PathwayBrowser/#/R-CEL-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Caenorhabditis elegans 57783 R-CEL-192036 https://reactome.org/PathwayBrowser/#/R-CEL-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Caenorhabditis elegans 57783 R-CEL-192067 https://reactome.org/PathwayBrowser/#/R-CEL-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Caenorhabditis elegans 57783 R-CEL-192160 https://reactome.org/PathwayBrowser/#/R-CEL-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Caenorhabditis elegans 57783 R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 57783 R-CEL-193064 https://reactome.org/PathwayBrowser/#/R-CEL-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Caenorhabditis elegans 57783 R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 57783 R-CEL-193746 https://reactome.org/PathwayBrowser/#/R-CEL-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Caenorhabditis elegans 57783 R-CEL-193755 https://reactome.org/PathwayBrowser/#/R-CEL-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Caenorhabditis elegans 57783 R-CEL-193758 https://reactome.org/PathwayBrowser/#/R-CEL-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Caenorhabditis elegans 57783 R-CEL-193781 https://reactome.org/PathwayBrowser/#/R-CEL-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Caenorhabditis elegans 57783 R-CEL-193800 https://reactome.org/PathwayBrowser/#/R-CEL-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Caenorhabditis elegans 57783 R-CEL-193821 https://reactome.org/PathwayBrowser/#/R-CEL-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Caenorhabditis elegans 57783 R-CEL-193824 https://reactome.org/PathwayBrowser/#/R-CEL-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Caenorhabditis elegans 57783 R-CEL-193841 https://reactome.org/PathwayBrowser/#/R-CEL-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Caenorhabditis elegans 57783 R-CEL-196060 https://reactome.org/PathwayBrowser/#/R-CEL-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Caenorhabditis elegans 57783 R-CEL-196402 https://reactome.org/PathwayBrowser/#/R-CEL-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Caenorhabditis elegans 57783 R-CEL-196417 https://reactome.org/PathwayBrowser/#/R-CEL-196417 Reduction of desmosterol to cholesterol IEA Caenorhabditis elegans 57783 R-CEL-197963 https://reactome.org/PathwayBrowser/#/R-CEL-197963 DHFR2 reduces FOLA to DHF IEA Caenorhabditis elegans 57783 R-CEL-197972 https://reactome.org/PathwayBrowser/#/R-CEL-197972 DHF is reduced to tetrahydrofolate (THF) IEA Caenorhabditis elegans 57783 R-CEL-200644 https://reactome.org/PathwayBrowser/#/R-CEL-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Caenorhabditis elegans 57783 R-CEL-200676 https://reactome.org/PathwayBrowser/#/R-CEL-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Caenorhabditis elegans 57783 R-CEL-200718 https://reactome.org/PathwayBrowser/#/R-CEL-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Caenorhabditis elegans 57783 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 57783 R-CEL-209845 https://reactome.org/PathwayBrowser/#/R-CEL-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Caenorhabditis elegans 57783 R-CEL-2161549 https://reactome.org/PathwayBrowser/#/R-CEL-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Caenorhabditis elegans 57783 R-CEL-2161614 https://reactome.org/PathwayBrowser/#/R-CEL-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Caenorhabditis elegans 57783 R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans 57783 R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Caenorhabditis elegans 57783 R-CEL-2395517 https://reactome.org/PathwayBrowser/#/R-CEL-2395517 NADPH transfers electrons to FDXR IEA Caenorhabditis elegans 57783 R-CEL-2465940 https://reactome.org/PathwayBrowser/#/R-CEL-2465940 atRAL is reduced to atROL IEA Caenorhabditis elegans 57783 R-CEL-2855252 https://reactome.org/PathwayBrowser/#/R-CEL-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Caenorhabditis elegans 57783 R-CEL-3149518 https://reactome.org/PathwayBrowser/#/R-CEL-3149518 MTRR reduces cob(II)alamin to meCbl IEA Caenorhabditis elegans 57783 R-CEL-3149519 https://reactome.org/PathwayBrowser/#/R-CEL-3149519 MMACHC decyanates CNCbl IEA Caenorhabditis elegans 57783 R-CEL-3323050 https://reactome.org/PathwayBrowser/#/R-CEL-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Caenorhabditis elegans 57783 R-CEL-3323079 https://reactome.org/PathwayBrowser/#/R-CEL-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 57783 R-CEL-389540 https://reactome.org/PathwayBrowser/#/R-CEL-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 57783 R-CEL-390425 https://reactome.org/PathwayBrowser/#/R-CEL-390425 FAR1 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 57783 R-CEL-390438 https://reactome.org/PathwayBrowser/#/R-CEL-390438 FAR2 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 57783 R-CEL-428123 https://reactome.org/PathwayBrowser/#/R-CEL-428123 KDSR reduces 3-ketosphingoid IEA Caenorhabditis elegans 57783 R-CEL-4419979 https://reactome.org/PathwayBrowser/#/R-CEL-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Caenorhabditis elegans 57783 R-CEL-450971 https://reactome.org/PathwayBrowser/#/R-CEL-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Caenorhabditis elegans 57783 R-CEL-450984 https://reactome.org/PathwayBrowser/#/R-CEL-450984 IDH2 dimer decarboxylates isocitrate IEA Caenorhabditis elegans 57783 R-CEL-469659 https://reactome.org/PathwayBrowser/#/R-CEL-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 57783 R-CEL-508040 https://reactome.org/PathwayBrowser/#/R-CEL-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Caenorhabditis elegans 57783 R-CEL-514604 https://reactome.org/PathwayBrowser/#/R-CEL-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Caenorhabditis elegans 57783 R-CEL-5263614 https://reactome.org/PathwayBrowser/#/R-CEL-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Caenorhabditis elegans 57783 R-CEL-5263616 https://reactome.org/PathwayBrowser/#/R-CEL-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Caenorhabditis elegans 57783 R-CEL-5340226 https://reactome.org/PathwayBrowser/#/R-CEL-5340226 CYGB dioxygenates NO IEA Caenorhabditis elegans 57783 R-CEL-5419165 https://reactome.org/PathwayBrowser/#/R-CEL-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Caenorhabditis elegans 57783 R-CEL-5423647 https://reactome.org/PathwayBrowser/#/R-CEL-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Caenorhabditis elegans 57783 R-CEL-548818 https://reactome.org/PathwayBrowser/#/R-CEL-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Caenorhabditis elegans 57783 R-CEL-548831 https://reactome.org/PathwayBrowser/#/R-CEL-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Caenorhabditis elegans 57783 R-CEL-5615668 https://reactome.org/PathwayBrowser/#/R-CEL-5615668 AKR1C3 reduces atRAL to atROL IEA Caenorhabditis elegans 57783 R-CEL-5652172 https://reactome.org/PathwayBrowser/#/R-CEL-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Caenorhabditis elegans 57783 R-CEL-5661240 https://reactome.org/PathwayBrowser/#/R-CEL-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Caenorhabditis elegans 57783 R-CEL-5661256 https://reactome.org/PathwayBrowser/#/R-CEL-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Caenorhabditis elegans 57783 R-CEL-5692232 https://reactome.org/PathwayBrowser/#/R-CEL-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Caenorhabditis elegans 57783 R-CEL-5692283 https://reactome.org/PathwayBrowser/#/R-CEL-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Caenorhabditis elegans 57783 R-CEL-5696822 https://reactome.org/PathwayBrowser/#/R-CEL-5696822 AKR1B15 reduces EST17b to E1 IEA Caenorhabditis elegans 57783 R-CEL-6786239 https://reactome.org/PathwayBrowser/#/R-CEL-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Caenorhabditis elegans 57783 R-CEL-6787642 https://reactome.org/PathwayBrowser/#/R-CEL-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Caenorhabditis elegans 57783 R-CEL-6806967 https://reactome.org/PathwayBrowser/#/R-CEL-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Caenorhabditis elegans 57783 R-CEL-6807055 https://reactome.org/PathwayBrowser/#/R-CEL-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Caenorhabditis elegans 57783 R-CEL-6807064 https://reactome.org/PathwayBrowser/#/R-CEL-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Caenorhabditis elegans 57783 R-CEL-6808487 https://reactome.org/PathwayBrowser/#/R-CEL-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 57783 R-CEL-6808496 https://reactome.org/PathwayBrowser/#/R-CEL-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 57783 R-CEL-70377 https://reactome.org/PathwayBrowser/#/R-CEL-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Caenorhabditis elegans 57783 R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Caenorhabditis elegans 57783 R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Caenorhabditis elegans 57783 R-CEL-70938 https://reactome.org/PathwayBrowser/#/R-CEL-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Caenorhabditis elegans 57783 R-CEL-71200 https://reactome.org/PathwayBrowser/#/R-CEL-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Caenorhabditis elegans 57783 R-CEL-71299 https://reactome.org/PathwayBrowser/#/R-CEL-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 57783 R-CEL-71682 https://reactome.org/PathwayBrowser/#/R-CEL-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 57783 R-CEL-73585 https://reactome.org/PathwayBrowser/#/R-CEL-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Caenorhabditis elegans 57783 R-CEL-73616 https://reactome.org/PathwayBrowser/#/R-CEL-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Caenorhabditis elegans 57783 R-CEL-73646 https://reactome.org/PathwayBrowser/#/R-CEL-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Caenorhabditis elegans 57783 R-CEL-75872 https://reactome.org/PathwayBrowser/#/R-CEL-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Caenorhabditis elegans 57783 R-CEL-75883 https://reactome.org/PathwayBrowser/#/R-CEL-75883 DHRS7B reduces GO3P to HXDG3P IEA Caenorhabditis elegans 57783 R-CEL-8865107 https://reactome.org/PathwayBrowser/#/R-CEL-8865107 MICAL1 produces NADP+, H2O2 IEA Caenorhabditis elegans 57783 R-CEL-8952873 https://reactome.org/PathwayBrowser/#/R-CEL-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Caenorhabditis elegans 57783 R-CEL-9012036 https://reactome.org/PathwayBrowser/#/R-CEL-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 57783 R-CEL-9012349 https://reactome.org/PathwayBrowser/#/R-CEL-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 57783 R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans 57783 R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 57783 R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 57783 R-CEL-9705713 https://reactome.org/PathwayBrowser/#/R-CEL-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 57783 R-CEL-9705714 https://reactome.org/PathwayBrowser/#/R-CEL-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 57783 R-CEL-9709098 https://reactome.org/PathwayBrowser/#/R-CEL-9709098 DHFR dimer reduces FOLA to DHF IEA Caenorhabditis elegans 57783 R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans 57783 R-CEL-9755937 https://reactome.org/PathwayBrowser/#/R-CEL-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Caenorhabditis elegans 57783 R-CEL-9758682 https://reactome.org/PathwayBrowser/#/R-CEL-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Caenorhabditis elegans 57783 R-CFA-1222376 https://reactome.org/PathwayBrowser/#/R-CFA-1222376 NOX2 generates superoxide from oxygen IEA Canis familiaris 57783 R-CFA-1475414 https://reactome.org/PathwayBrowser/#/R-CFA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Canis familiaris 57783 R-CFA-1497869 https://reactome.org/PathwayBrowser/#/R-CFA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Canis familiaris 57783 R-CFA-156526 https://reactome.org/PathwayBrowser/#/R-CFA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Canis familiaris 57783 R-CFA-1655453 https://reactome.org/PathwayBrowser/#/R-CFA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Canis familiaris 57783 R-CFA-189384 https://reactome.org/PathwayBrowser/#/R-CFA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Canis familiaris 57783 R-CFA-189398 https://reactome.org/PathwayBrowser/#/R-CFA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Canis familiaris 57783 R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 57783 R-CFA-191352 https://reactome.org/PathwayBrowser/#/R-CFA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Canis familiaris 57783 R-CFA-191402 https://reactome.org/PathwayBrowser/#/R-CFA-191402 Reduction of presqualene diphosphate to form squalene IEA Canis familiaris 57783 R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 57783 R-CFA-191999 https://reactome.org/PathwayBrowser/#/R-CFA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Canis familiaris 57783 R-CFA-192033 https://reactome.org/PathwayBrowser/#/R-CFA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Canis familiaris 57783 R-CFA-192042 https://reactome.org/PathwayBrowser/#/R-CFA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 57783 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 57783 R-CFA-192054 https://reactome.org/PathwayBrowser/#/R-CFA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Canis familiaris 57783 R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 57783 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 57783 R-CFA-192067 https://reactome.org/PathwayBrowser/#/R-CFA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Canis familiaris 57783 R-CFA-192123 https://reactome.org/PathwayBrowser/#/R-CFA-192123 CYP27A1 27-hydroxylates CHOL IEA Canis familiaris 57783 R-CFA-192157 https://reactome.org/PathwayBrowser/#/R-CFA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Canis familiaris 57783 R-CFA-192178 https://reactome.org/PathwayBrowser/#/R-CFA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Canis familiaris 57783 R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 57783 R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 57783 R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 57783 R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 57783 R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 57783 R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 57783 R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 57783 R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 57783 R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 57783 R-CFA-193393 https://reactome.org/PathwayBrowser/#/R-CFA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Canis familiaris 57783 R-CFA-193460 https://reactome.org/PathwayBrowser/#/R-CFA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Canis familiaris 57783 R-CFA-193497 https://reactome.org/PathwayBrowser/#/R-CFA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Canis familiaris 57783 R-CFA-193709 https://reactome.org/PathwayBrowser/#/R-CFA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Canis familiaris 57783 R-CFA-193713 https://reactome.org/PathwayBrowser/#/R-CFA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Canis familiaris 57783 R-CFA-193719 https://reactome.org/PathwayBrowser/#/R-CFA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 57783 R-CFA-193737 https://reactome.org/PathwayBrowser/#/R-CFA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Canis familiaris 57783 R-CFA-193746 https://reactome.org/PathwayBrowser/#/R-CFA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Canis familiaris 57783 R-CFA-193755 https://reactome.org/PathwayBrowser/#/R-CFA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Canis familiaris 57783 R-CFA-193780 https://reactome.org/PathwayBrowser/#/R-CFA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Canis familiaris 57783 R-CFA-193787 https://reactome.org/PathwayBrowser/#/R-CFA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Canis familiaris 57783 R-CFA-193792 https://reactome.org/PathwayBrowser/#/R-CFA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Canis familiaris 57783 R-CFA-193821 https://reactome.org/PathwayBrowser/#/R-CFA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Canis familiaris 57783 R-CFA-193824 https://reactome.org/PathwayBrowser/#/R-CFA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Canis familiaris 57783 R-CFA-193845 https://reactome.org/PathwayBrowser/#/R-CFA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Canis familiaris 57783 R-CFA-193964 https://reactome.org/PathwayBrowser/#/R-CFA-193964 CYP21A2 21-hydroxylates PROG IEA Canis familiaris 57783 R-CFA-193965 https://reactome.org/PathwayBrowser/#/R-CFA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Canis familiaris 57783 R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 57783 R-CFA-193995 https://reactome.org/PathwayBrowser/#/R-CFA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Canis familiaris 57783 R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 57783 R-CFA-194017 https://reactome.org/PathwayBrowser/#/R-CFA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Canis familiaris 57783 R-CFA-194023 https://reactome.org/PathwayBrowser/#/R-CFA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Canis familiaris 57783 R-CFA-194632 https://reactome.org/PathwayBrowser/#/R-CFA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Canis familiaris 57783 R-CFA-194641 https://reactome.org/PathwayBrowser/#/R-CFA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 57783 R-CFA-194669 https://reactome.org/PathwayBrowser/#/R-CFA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 57783 R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 57783 R-CFA-194689 https://reactome.org/PathwayBrowser/#/R-CFA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 57783 R-CFA-194698 https://reactome.org/PathwayBrowser/#/R-CFA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Canis familiaris 57783 R-CFA-195664 https://reactome.org/PathwayBrowser/#/R-CFA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Canis familiaris 57783 R-CFA-196060 https://reactome.org/PathwayBrowser/#/R-CFA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Canis familiaris 57783 R-CFA-196402 https://reactome.org/PathwayBrowser/#/R-CFA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Canis familiaris 57783 R-CFA-196417 https://reactome.org/PathwayBrowser/#/R-CFA-196417 Reduction of desmosterol to cholesterol IEA Canis familiaris 57783 R-CFA-197963 https://reactome.org/PathwayBrowser/#/R-CFA-197963 DHFR2 reduces FOLA to DHF IEA Canis familiaris 57783 R-CFA-197972 https://reactome.org/PathwayBrowser/#/R-CFA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Canis familiaris 57783 R-CFA-200644 https://reactome.org/PathwayBrowser/#/R-CFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Canis familiaris 57783 R-CFA-200676 https://reactome.org/PathwayBrowser/#/R-CFA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Canis familiaris 57783 R-CFA-200718 https://reactome.org/PathwayBrowser/#/R-CFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Canis familiaris 57783 R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 57783 R-CFA-209772 https://reactome.org/PathwayBrowser/#/R-CFA-209772 Thyroxine is deiodinated to triiodothyronine IEA Canis familiaris 57783 R-CFA-209845 https://reactome.org/PathwayBrowser/#/R-CFA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Canis familiaris 57783 R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 57783 R-CFA-211873 https://reactome.org/PathwayBrowser/#/R-CFA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Canis familiaris 57783 R-CFA-211923 https://reactome.org/PathwayBrowser/#/R-CFA-211923 CYP26C1 4-hydroxylates 9cRA IEA Canis familiaris 57783 R-CFA-211950 https://reactome.org/PathwayBrowser/#/R-CFA-211950 CYP24A1 24-hydroxylates CTL IEA Canis familiaris 57783 R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 57783 R-CFA-2161651 https://reactome.org/PathwayBrowser/#/R-CFA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Canis familiaris 57783 R-CFA-2161745 https://reactome.org/PathwayBrowser/#/R-CFA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Canis familiaris 57783 R-CFA-2161792 https://reactome.org/PathwayBrowser/#/R-CFA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Canis familiaris 57783 R-CFA-2161890 https://reactome.org/PathwayBrowser/#/R-CFA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Canis familiaris 57783 R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Canis familiaris 57783 R-CFA-2161951 https://reactome.org/PathwayBrowser/#/R-CFA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Canis familiaris 57783 R-CFA-2395517 https://reactome.org/PathwayBrowser/#/R-CFA-2395517 NADPH transfers electrons to FDXR IEA Canis familiaris 57783 R-CFA-2464822 https://reactome.org/PathwayBrowser/#/R-CFA-2464822 RDH12 reduces atRAL to atROL IEA Canis familiaris 57783 R-CFA-2465940 https://reactome.org/PathwayBrowser/#/R-CFA-2465940 atRAL is reduced to atROL IEA Canis familiaris 57783 R-CFA-3149518 https://reactome.org/PathwayBrowser/#/R-CFA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Canis familiaris 57783 R-CFA-3149519 https://reactome.org/PathwayBrowser/#/R-CFA-3149519 MMACHC decyanates CNCbl IEA Canis familiaris 57783 R-CFA-3323079 https://reactome.org/PathwayBrowser/#/R-CFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 57783 R-CFA-389540 https://reactome.org/PathwayBrowser/#/R-CFA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 57783 R-CFA-390425 https://reactome.org/PathwayBrowser/#/R-CFA-390425 FAR1 reduces PalmCoA to HXOL IEA Canis familiaris 57783 R-CFA-390438 https://reactome.org/PathwayBrowser/#/R-CFA-390438 FAR2 reduces PalmCoA to HXOL IEA Canis familiaris 57783 R-CFA-418436 https://reactome.org/PathwayBrowser/#/R-CFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Canis familiaris 57783 R-CFA-428123 https://reactome.org/PathwayBrowser/#/R-CFA-428123 KDSR reduces 3-ketosphingoid IEA Canis familiaris 57783 R-CFA-4419979 https://reactome.org/PathwayBrowser/#/R-CFA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Canis familiaris 57783 R-CFA-450971 https://reactome.org/PathwayBrowser/#/R-CFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Canis familiaris 57783 R-CFA-450984 https://reactome.org/PathwayBrowser/#/R-CFA-450984 IDH2 dimer decarboxylates isocitrate IEA Canis familiaris 57783 R-CFA-469659 https://reactome.org/PathwayBrowser/#/R-CFA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Canis familiaris 57783 R-CFA-508040 https://reactome.org/PathwayBrowser/#/R-CFA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Canis familiaris 57783 R-CFA-514604 https://reactome.org/PathwayBrowser/#/R-CFA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Canis familiaris 57783 R-CFA-5218841 https://reactome.org/PathwayBrowser/#/R-CFA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Canis familiaris 57783 R-CFA-5340226 https://reactome.org/PathwayBrowser/#/R-CFA-5340226 CYGB dioxygenates NO IEA Canis familiaris 57783 R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 57783 R-CFA-5419165 https://reactome.org/PathwayBrowser/#/R-CFA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Canis familiaris 57783 R-CFA-5423637 https://reactome.org/PathwayBrowser/#/R-CFA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Canis familiaris 57783 R-CFA-5423647 https://reactome.org/PathwayBrowser/#/R-CFA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Canis familiaris 57783 R-CFA-5423664 https://reactome.org/PathwayBrowser/#/R-CFA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Canis familiaris 57783 R-CFA-5423672 https://reactome.org/PathwayBrowser/#/R-CFA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Canis familiaris 57783 R-CFA-548818 https://reactome.org/PathwayBrowser/#/R-CFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Canis familiaris 57783 R-CFA-548831 https://reactome.org/PathwayBrowser/#/R-CFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Canis familiaris 57783 R-CFA-5602295 https://reactome.org/PathwayBrowser/#/R-CFA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Canis familiaris 57783 R-CFA-5652172 https://reactome.org/PathwayBrowser/#/R-CFA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Canis familiaris 57783 R-CFA-5661240 https://reactome.org/PathwayBrowser/#/R-CFA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Canis familiaris 57783 R-CFA-5661256 https://reactome.org/PathwayBrowser/#/R-CFA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Canis familiaris 57783 R-CFA-5668629 https://reactome.org/PathwayBrowser/#/R-CFA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Canis familiaris 57783 R-CFA-5668718 https://reactome.org/PathwayBrowser/#/R-CFA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 57783 R-CFA-5668731 https://reactome.org/PathwayBrowser/#/R-CFA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 57783 R-CFA-5692232 https://reactome.org/PathwayBrowser/#/R-CFA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Canis familiaris 57783 R-CFA-5692283 https://reactome.org/PathwayBrowser/#/R-CFA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Canis familiaris 57783 R-CFA-5693390 https://reactome.org/PathwayBrowser/#/R-CFA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Canis familiaris 57783 R-CFA-6783955 https://reactome.org/PathwayBrowser/#/R-CFA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 57783 R-CFA-6786239 https://reactome.org/PathwayBrowser/#/R-CFA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Canis familiaris 57783 R-CFA-6787642 https://reactome.org/PathwayBrowser/#/R-CFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Canis familiaris 57783 R-CFA-6789092 https://reactome.org/PathwayBrowser/#/R-CFA-6789092 NOX2 generates superoxide anion from oxygen IEA Canis familiaris 57783 R-CFA-6799722 https://reactome.org/PathwayBrowser/#/R-CFA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Canis familiaris 57783 R-CFA-6806967 https://reactome.org/PathwayBrowser/#/R-CFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Canis familiaris 57783 R-CFA-6807053 https://reactome.org/PathwayBrowser/#/R-CFA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Canis familiaris 57783 R-CFA-6807055 https://reactome.org/PathwayBrowser/#/R-CFA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Canis familiaris 57783 R-CFA-6807064 https://reactome.org/PathwayBrowser/#/R-CFA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Canis familiaris 57783 R-CFA-6807557 https://reactome.org/PathwayBrowser/#/R-CFA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Canis familiaris 57783 R-CFA-6808487 https://reactome.org/PathwayBrowser/#/R-CFA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 57783 R-CFA-6808496 https://reactome.org/PathwayBrowser/#/R-CFA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 57783 R-CFA-70377 https://reactome.org/PathwayBrowser/#/R-CFA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Canis familiaris 57783 R-CFA-70577 https://reactome.org/PathwayBrowser/#/R-CFA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Canis familiaris 57783 R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Canis familiaris 57783 R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Canis familiaris 57783 R-CFA-70938 https://reactome.org/PathwayBrowser/#/R-CFA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Canis familiaris 57783 R-CFA-71200 https://reactome.org/PathwayBrowser/#/R-CFA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Canis familiaris 57783 R-CFA-71299 https://reactome.org/PathwayBrowser/#/R-CFA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Canis familiaris 57783 R-CFA-71682 https://reactome.org/PathwayBrowser/#/R-CFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 57783 R-CFA-73585 https://reactome.org/PathwayBrowser/#/R-CFA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Canis familiaris 57783 R-CFA-73616 https://reactome.org/PathwayBrowser/#/R-CFA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Canis familiaris 57783 R-CFA-74872 https://reactome.org/PathwayBrowser/#/R-CFA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Canis familiaris 57783 R-CFA-75872 https://reactome.org/PathwayBrowser/#/R-CFA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Canis familiaris 57783 R-CFA-75883 https://reactome.org/PathwayBrowser/#/R-CFA-75883 DHRS7B reduces GO3P to HXDG3P IEA Canis familiaris 57783 R-CFA-804969 https://reactome.org/PathwayBrowser/#/R-CFA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Canis familiaris 57783 R-CFA-8862137 https://reactome.org/PathwayBrowser/#/R-CFA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Canis familiaris 57783 R-CFA-8862152 https://reactome.org/PathwayBrowser/#/R-CFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Canis familiaris 57783 R-CFA-8937419 https://reactome.org/PathwayBrowser/#/R-CFA-8937419 CBR3 reduces DOX to DOXOL IEA Canis familiaris 57783 R-CFA-8952873 https://reactome.org/PathwayBrowser/#/R-CFA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Canis familiaris 57783 R-CFA-9012036 https://reactome.org/PathwayBrowser/#/R-CFA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Canis familiaris 57783 R-CFA-9012349 https://reactome.org/PathwayBrowser/#/R-CFA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Canis familiaris 57783 R-CFA-9020255 https://reactome.org/PathwayBrowser/#/R-CFA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Canis familiaris 57783 R-CFA-9020256 https://reactome.org/PathwayBrowser/#/R-CFA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Canis familiaris 57783 R-CFA-9020262 https://reactome.org/PathwayBrowser/#/R-CFA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Canis familiaris 57783 R-CFA-9020277 https://reactome.org/PathwayBrowser/#/R-CFA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Canis familiaris 57783 R-CFA-9020278 https://reactome.org/PathwayBrowser/#/R-CFA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Canis familiaris 57783 R-CFA-9024881 https://reactome.org/PathwayBrowser/#/R-CFA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Canis familiaris 57783 R-CFA-9024983 https://reactome.org/PathwayBrowser/#/R-CFA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Canis familiaris 57783 R-CFA-9025995 https://reactome.org/PathwayBrowser/#/R-CFA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Canis familiaris 57783 R-CFA-9025999 https://reactome.org/PathwayBrowser/#/R-CFA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Canis familiaris 57783 R-CFA-9026007 https://reactome.org/PathwayBrowser/#/R-CFA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Canis familiaris 57783 R-CFA-9027043 https://reactome.org/PathwayBrowser/#/R-CFA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Canis familiaris 57783 R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 57783 R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 57783 R-CFA-917811 https://reactome.org/PathwayBrowser/#/R-CFA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Canis familiaris 57783 R-CFA-9705713 https://reactome.org/PathwayBrowser/#/R-CFA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Canis familiaris 57783 R-CFA-9705714 https://reactome.org/PathwayBrowser/#/R-CFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Canis familiaris 57783 R-CFA-9709098 https://reactome.org/PathwayBrowser/#/R-CFA-9709098 DHFR dimer reduces FOLA to DHF IEA Canis familiaris 57783 R-CFA-9753285 https://reactome.org/PathwayBrowser/#/R-CFA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Canis familiaris 57783 R-CFA-9755937 https://reactome.org/PathwayBrowser/#/R-CFA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Canis familiaris 57783 R-CFA-9756138 https://reactome.org/PathwayBrowser/#/R-CFA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Canis familiaris 57783 R-CFA-9756162 https://reactome.org/PathwayBrowser/#/R-CFA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Canis familiaris 57783 R-CFA-9756169 https://reactome.org/PathwayBrowser/#/R-CFA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Canis familiaris 57783 R-CFA-9756180 https://reactome.org/PathwayBrowser/#/R-CFA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Canis familiaris 57783 R-CFA-9757706 https://reactome.org/PathwayBrowser/#/R-CFA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Canis familiaris 57783 R-CFA-9759259 https://reactome.org/PathwayBrowser/#/R-CFA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Canis familiaris 57783 R-DDI-1475414 https://reactome.org/PathwayBrowser/#/R-DDI-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Dictyostelium discoideum 57783 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 57783 R-DDI-1497869 https://reactome.org/PathwayBrowser/#/R-DDI-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Dictyostelium discoideum 57783 R-DDI-156526 https://reactome.org/PathwayBrowser/#/R-DDI-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Dictyostelium discoideum 57783 R-DDI-1655453 https://reactome.org/PathwayBrowser/#/R-DDI-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Dictyostelium discoideum 57783 R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 57783 R-DDI-191352 https://reactome.org/PathwayBrowser/#/R-DDI-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Dictyostelium discoideum 57783 R-DDI-191402 https://reactome.org/PathwayBrowser/#/R-DDI-191402 Reduction of presqualene diphosphate to form squalene IEA Dictyostelium discoideum 57783 R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 57783 R-DDI-192033 https://reactome.org/PathwayBrowser/#/R-DDI-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Dictyostelium discoideum 57783 R-DDI-192036 https://reactome.org/PathwayBrowser/#/R-DDI-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Dictyostelium discoideum 57783 R-DDI-192067 https://reactome.org/PathwayBrowser/#/R-DDI-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Dictyostelium discoideum 57783 R-DDI-192160 https://reactome.org/PathwayBrowser/#/R-DDI-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Dictyostelium discoideum 57783 R-DDI-193064 https://reactome.org/PathwayBrowser/#/R-DDI-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Dictyostelium discoideum 57783 R-DDI-193746 https://reactome.org/PathwayBrowser/#/R-DDI-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Dictyostelium discoideum 57783 R-DDI-193755 https://reactome.org/PathwayBrowser/#/R-DDI-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Dictyostelium discoideum 57783 R-DDI-193758 https://reactome.org/PathwayBrowser/#/R-DDI-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Dictyostelium discoideum 57783 R-DDI-193781 https://reactome.org/PathwayBrowser/#/R-DDI-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Dictyostelium discoideum 57783 R-DDI-193800 https://reactome.org/PathwayBrowser/#/R-DDI-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Dictyostelium discoideum 57783 R-DDI-193821 https://reactome.org/PathwayBrowser/#/R-DDI-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Dictyostelium discoideum 57783 R-DDI-193824 https://reactome.org/PathwayBrowser/#/R-DDI-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Dictyostelium discoideum 57783 R-DDI-193841 https://reactome.org/PathwayBrowser/#/R-DDI-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Dictyostelium discoideum 57783 R-DDI-193964 https://reactome.org/PathwayBrowser/#/R-DDI-193964 CYP21A2 21-hydroxylates PROG IEA Dictyostelium discoideum 57783 R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 57783 R-DDI-194641 https://reactome.org/PathwayBrowser/#/R-DDI-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 57783 R-DDI-194669 https://reactome.org/PathwayBrowser/#/R-DDI-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 57783 R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 57783 R-DDI-194698 https://reactome.org/PathwayBrowser/#/R-DDI-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Dictyostelium discoideum 57783 R-DDI-196060 https://reactome.org/PathwayBrowser/#/R-DDI-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Dictyostelium discoideum 57783 R-DDI-197963 https://reactome.org/PathwayBrowser/#/R-DDI-197963 DHFR2 reduces FOLA to DHF IEA Dictyostelium discoideum 57783 R-DDI-197972 https://reactome.org/PathwayBrowser/#/R-DDI-197972 DHF is reduced to tetrahydrofolate (THF) IEA Dictyostelium discoideum 57783 R-DDI-200644 https://reactome.org/PathwayBrowser/#/R-DDI-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Dictyostelium discoideum 57783 R-DDI-200676 https://reactome.org/PathwayBrowser/#/R-DDI-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Dictyostelium discoideum 57783 R-DDI-200718 https://reactome.org/PathwayBrowser/#/R-DDI-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Dictyostelium discoideum 57783 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 57783 R-DDI-209772 https://reactome.org/PathwayBrowser/#/R-DDI-209772 Thyroxine is deiodinated to triiodothyronine IEA Dictyostelium discoideum 57783 R-DDI-209845 https://reactome.org/PathwayBrowser/#/R-DDI-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Dictyostelium discoideum 57783 R-DDI-2161549 https://reactome.org/PathwayBrowser/#/R-DDI-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Dictyostelium discoideum 57783 R-DDI-2161614 https://reactome.org/PathwayBrowser/#/R-DDI-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Dictyostelium discoideum 57783 R-DDI-2161890 https://reactome.org/PathwayBrowser/#/R-DDI-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Dictyostelium discoideum 57783 R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Dictyostelium discoideum 57783 R-DDI-2395517 https://reactome.org/PathwayBrowser/#/R-DDI-2395517 NADPH transfers electrons to FDXR IEA Dictyostelium discoideum 57783 R-DDI-3149518 https://reactome.org/PathwayBrowser/#/R-DDI-3149518 MTRR reduces cob(II)alamin to meCbl IEA Dictyostelium discoideum 57783 R-DDI-3149519 https://reactome.org/PathwayBrowser/#/R-DDI-3149519 MMACHC decyanates CNCbl IEA Dictyostelium discoideum 57783 R-DDI-3323079 https://reactome.org/PathwayBrowser/#/R-DDI-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 57783 R-DDI-350869 https://reactome.org/PathwayBrowser/#/R-DDI-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Dictyostelium discoideum 57783 R-DDI-389540 https://reactome.org/PathwayBrowser/#/R-DDI-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 57783 R-DDI-390425 https://reactome.org/PathwayBrowser/#/R-DDI-390425 FAR1 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 57783 R-DDI-390438 https://reactome.org/PathwayBrowser/#/R-DDI-390438 FAR2 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 57783 R-DDI-418436 https://reactome.org/PathwayBrowser/#/R-DDI-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Dictyostelium discoideum 57783 R-DDI-428123 https://reactome.org/PathwayBrowser/#/R-DDI-428123 KDSR reduces 3-ketosphingoid IEA Dictyostelium discoideum 57783 R-DDI-4419979 https://reactome.org/PathwayBrowser/#/R-DDI-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Dictyostelium discoideum 57783 R-DDI-450971 https://reactome.org/PathwayBrowser/#/R-DDI-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Dictyostelium discoideum 57783 R-DDI-5419165 https://reactome.org/PathwayBrowser/#/R-DDI-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Dictyostelium discoideum 57783 R-DDI-5423647 https://reactome.org/PathwayBrowser/#/R-DDI-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Dictyostelium discoideum 57783 R-DDI-548818 https://reactome.org/PathwayBrowser/#/R-DDI-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Dictyostelium discoideum 57783 R-DDI-548831 https://reactome.org/PathwayBrowser/#/R-DDI-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Dictyostelium discoideum 57783 R-DDI-5615668 https://reactome.org/PathwayBrowser/#/R-DDI-5615668 AKR1C3 reduces atRAL to atROL IEA Dictyostelium discoideum 57783 R-DDI-5652172 https://reactome.org/PathwayBrowser/#/R-DDI-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Dictyostelium discoideum 57783 R-DDI-5661256 https://reactome.org/PathwayBrowser/#/R-DDI-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Dictyostelium discoideum 57783 R-DDI-5692232 https://reactome.org/PathwayBrowser/#/R-DDI-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Dictyostelium discoideum 57783 R-DDI-5692283 https://reactome.org/PathwayBrowser/#/R-DDI-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Dictyostelium discoideum 57783 R-DDI-5696822 https://reactome.org/PathwayBrowser/#/R-DDI-5696822 AKR1B15 reduces EST17b to E1 IEA Dictyostelium discoideum 57783 R-DDI-6783955 https://reactome.org/PathwayBrowser/#/R-DDI-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 57783 R-DDI-6787642 https://reactome.org/PathwayBrowser/#/R-DDI-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Dictyostelium discoideum 57783 R-DDI-6799722 https://reactome.org/PathwayBrowser/#/R-DDI-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Dictyostelium discoideum 57783 R-DDI-6806967 https://reactome.org/PathwayBrowser/#/R-DDI-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Dictyostelium discoideum 57783 R-DDI-6807557 https://reactome.org/PathwayBrowser/#/R-DDI-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Dictyostelium discoideum 57783 R-DDI-70377 https://reactome.org/PathwayBrowser/#/R-DDI-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Dictyostelium discoideum 57783 R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Dictyostelium discoideum 57783 R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Dictyostelium discoideum 57783 R-DDI-70938 https://reactome.org/PathwayBrowser/#/R-DDI-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Dictyostelium discoideum 57783 R-DDI-71200 https://reactome.org/PathwayBrowser/#/R-DDI-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Dictyostelium discoideum 57783 R-DDI-71299 https://reactome.org/PathwayBrowser/#/R-DDI-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 57783 R-DDI-71682 https://reactome.org/PathwayBrowser/#/R-DDI-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 57783 R-DDI-73585 https://reactome.org/PathwayBrowser/#/R-DDI-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Dictyostelium discoideum 57783 R-DDI-73616 https://reactome.org/PathwayBrowser/#/R-DDI-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Dictyostelium discoideum 57783 R-DDI-75872 https://reactome.org/PathwayBrowser/#/R-DDI-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Dictyostelium discoideum 57783 R-DDI-804969 https://reactome.org/PathwayBrowser/#/R-DDI-804969 HSD17B1 hydrogenates E1 to EST17b IEA Dictyostelium discoideum 57783 R-DDI-8862152 https://reactome.org/PathwayBrowser/#/R-DDI-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Dictyostelium discoideum 57783 R-DDI-8865107 https://reactome.org/PathwayBrowser/#/R-DDI-8865107 MICAL1 produces NADP+, H2O2 IEA Dictyostelium discoideum 57783 R-DDI-8952873 https://reactome.org/PathwayBrowser/#/R-DDI-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Dictyostelium discoideum 57783 R-DDI-9020255 https://reactome.org/PathwayBrowser/#/R-DDI-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Dictyostelium discoideum 57783 R-DDI-9020256 https://reactome.org/PathwayBrowser/#/R-DDI-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Dictyostelium discoideum 57783 R-DDI-9020262 https://reactome.org/PathwayBrowser/#/R-DDI-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Dictyostelium discoideum 57783 R-DDI-9020277 https://reactome.org/PathwayBrowser/#/R-DDI-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Dictyostelium discoideum 57783 R-DDI-9020278 https://reactome.org/PathwayBrowser/#/R-DDI-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Dictyostelium discoideum 57783 R-DDI-9024881 https://reactome.org/PathwayBrowser/#/R-DDI-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Dictyostelium discoideum 57783 R-DDI-9024983 https://reactome.org/PathwayBrowser/#/R-DDI-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Dictyostelium discoideum 57783 R-DDI-9025995 https://reactome.org/PathwayBrowser/#/R-DDI-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Dictyostelium discoideum 57783 R-DDI-9025999 https://reactome.org/PathwayBrowser/#/R-DDI-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Dictyostelium discoideum 57783 R-DDI-9026007 https://reactome.org/PathwayBrowser/#/R-DDI-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Dictyostelium discoideum 57783 R-DDI-9027043 https://reactome.org/PathwayBrowser/#/R-DDI-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Dictyostelium discoideum 57783 R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 57783 R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 57783 R-DDI-9705714 https://reactome.org/PathwayBrowser/#/R-DDI-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Dictyostelium discoideum 57783 R-DDI-9709098 https://reactome.org/PathwayBrowser/#/R-DDI-9709098 DHFR dimer reduces FOLA to DHF IEA Dictyostelium discoideum 57783 R-DDI-9753285 https://reactome.org/PathwayBrowser/#/R-DDI-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Dictyostelium discoideum 57783 R-DDI-9758682 https://reactome.org/PathwayBrowser/#/R-DDI-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Dictyostelium discoideum 57783 R-DME-1475414 https://reactome.org/PathwayBrowser/#/R-DME-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Drosophila melanogaster 57783 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 57783 R-DME-1497869 https://reactome.org/PathwayBrowser/#/R-DME-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Drosophila melanogaster 57783 R-DME-156526 https://reactome.org/PathwayBrowser/#/R-DME-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Drosophila melanogaster 57783 R-DME-189384 https://reactome.org/PathwayBrowser/#/R-DME-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Drosophila melanogaster 57783 R-DME-189398 https://reactome.org/PathwayBrowser/#/R-DME-189398 HMOX1 dimer, HMOX2 cleave heme IEA Drosophila melanogaster 57783 R-DME-191352 https://reactome.org/PathwayBrowser/#/R-DME-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Drosophila melanogaster 57783 R-DME-192033 https://reactome.org/PathwayBrowser/#/R-DME-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Drosophila melanogaster 57783 R-DME-192036 https://reactome.org/PathwayBrowser/#/R-DME-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Drosophila melanogaster 57783 R-DME-192067 https://reactome.org/PathwayBrowser/#/R-DME-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Drosophila melanogaster 57783 R-DME-192160 https://reactome.org/PathwayBrowser/#/R-DME-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Drosophila melanogaster 57783 R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 57783 R-DME-193064 https://reactome.org/PathwayBrowser/#/R-DME-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Drosophila melanogaster 57783 R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 57783 R-DME-193746 https://reactome.org/PathwayBrowser/#/R-DME-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Drosophila melanogaster 57783 R-DME-193755 https://reactome.org/PathwayBrowser/#/R-DME-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Drosophila melanogaster 57783 R-DME-193758 https://reactome.org/PathwayBrowser/#/R-DME-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Drosophila melanogaster 57783 R-DME-193781 https://reactome.org/PathwayBrowser/#/R-DME-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Drosophila melanogaster 57783 R-DME-193800 https://reactome.org/PathwayBrowser/#/R-DME-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Drosophila melanogaster 57783 R-DME-193821 https://reactome.org/PathwayBrowser/#/R-DME-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Drosophila melanogaster 57783 R-DME-193824 https://reactome.org/PathwayBrowser/#/R-DME-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Drosophila melanogaster 57783 R-DME-193841 https://reactome.org/PathwayBrowser/#/R-DME-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Drosophila melanogaster 57783 R-DME-194023 https://reactome.org/PathwayBrowser/#/R-DME-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Drosophila melanogaster 57783 R-DME-194698 https://reactome.org/PathwayBrowser/#/R-DME-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Drosophila melanogaster 57783 R-DME-196060 https://reactome.org/PathwayBrowser/#/R-DME-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Drosophila melanogaster 57783 R-DME-197963 https://reactome.org/PathwayBrowser/#/R-DME-197963 DHFR2 reduces FOLA to DHF IEA Drosophila melanogaster 57783 R-DME-197972 https://reactome.org/PathwayBrowser/#/R-DME-197972 DHF is reduced to tetrahydrofolate (THF) IEA Drosophila melanogaster 57783 R-DME-200644 https://reactome.org/PathwayBrowser/#/R-DME-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Drosophila melanogaster 57783 R-DME-200676 https://reactome.org/PathwayBrowser/#/R-DME-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Drosophila melanogaster 57783 R-DME-200718 https://reactome.org/PathwayBrowser/#/R-DME-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Drosophila melanogaster 57783 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 57783 R-DME-209845 https://reactome.org/PathwayBrowser/#/R-DME-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Drosophila melanogaster 57783 R-DME-2161549 https://reactome.org/PathwayBrowser/#/R-DME-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Drosophila melanogaster 57783 R-DME-2161614 https://reactome.org/PathwayBrowser/#/R-DME-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Drosophila melanogaster 57783 R-DME-2161890 https://reactome.org/PathwayBrowser/#/R-DME-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Drosophila melanogaster 57783 R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Drosophila melanogaster 57783 R-DME-2395517 https://reactome.org/PathwayBrowser/#/R-DME-2395517 NADPH transfers electrons to FDXR IEA Drosophila melanogaster 57783 R-DME-2464822 https://reactome.org/PathwayBrowser/#/R-DME-2464822 RDH12 reduces atRAL to atROL IEA Drosophila melanogaster 57783 R-DME-2465940 https://reactome.org/PathwayBrowser/#/R-DME-2465940 atRAL is reduced to atROL IEA Drosophila melanogaster 57783 R-DME-2855252 https://reactome.org/PathwayBrowser/#/R-DME-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 57783 R-DME-3323050 https://reactome.org/PathwayBrowser/#/R-DME-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Drosophila melanogaster 57783 R-DME-389540 https://reactome.org/PathwayBrowser/#/R-DME-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 57783 R-DME-390425 https://reactome.org/PathwayBrowser/#/R-DME-390425 FAR1 reduces PalmCoA to HXOL IEA Drosophila melanogaster 57783 R-DME-390438 https://reactome.org/PathwayBrowser/#/R-DME-390438 FAR2 reduces PalmCoA to HXOL IEA Drosophila melanogaster 57783 R-DME-418436 https://reactome.org/PathwayBrowser/#/R-DME-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Drosophila melanogaster 57783 R-DME-428123 https://reactome.org/PathwayBrowser/#/R-DME-428123 KDSR reduces 3-ketosphingoid IEA Drosophila melanogaster 57783 R-DME-4419979 https://reactome.org/PathwayBrowser/#/R-DME-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Drosophila melanogaster 57783 R-DME-508040 https://reactome.org/PathwayBrowser/#/R-DME-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Drosophila melanogaster 57783 R-DME-5419165 https://reactome.org/PathwayBrowser/#/R-DME-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Drosophila melanogaster 57783 R-DME-5423647 https://reactome.org/PathwayBrowser/#/R-DME-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Drosophila melanogaster 57783 R-DME-548818 https://reactome.org/PathwayBrowser/#/R-DME-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Drosophila melanogaster 57783 R-DME-548831 https://reactome.org/PathwayBrowser/#/R-DME-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Drosophila melanogaster 57783 R-DME-5615668 https://reactome.org/PathwayBrowser/#/R-DME-5615668 AKR1C3 reduces atRAL to atROL IEA Drosophila melanogaster 57783 R-DME-5652172 https://reactome.org/PathwayBrowser/#/R-DME-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Drosophila melanogaster 57783 R-DME-5661240 https://reactome.org/PathwayBrowser/#/R-DME-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Drosophila melanogaster 57783 R-DME-5661256 https://reactome.org/PathwayBrowser/#/R-DME-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Drosophila melanogaster 57783 R-DME-5692232 https://reactome.org/PathwayBrowser/#/R-DME-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Drosophila melanogaster 57783 R-DME-5692283 https://reactome.org/PathwayBrowser/#/R-DME-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Drosophila melanogaster 57783 R-DME-5693390 https://reactome.org/PathwayBrowser/#/R-DME-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Drosophila melanogaster 57783 R-DME-5696822 https://reactome.org/PathwayBrowser/#/R-DME-5696822 AKR1B15 reduces EST17b to E1 IEA Drosophila melanogaster 57783 R-DME-6786239 https://reactome.org/PathwayBrowser/#/R-DME-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Drosophila melanogaster 57783 R-DME-6787642 https://reactome.org/PathwayBrowser/#/R-DME-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Drosophila melanogaster 57783 R-DME-6806967 https://reactome.org/PathwayBrowser/#/R-DME-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Drosophila melanogaster 57783 R-DME-6807557 https://reactome.org/PathwayBrowser/#/R-DME-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Drosophila melanogaster 57783 R-DME-6808487 https://reactome.org/PathwayBrowser/#/R-DME-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 57783 R-DME-6808496 https://reactome.org/PathwayBrowser/#/R-DME-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 57783 R-DME-70377 https://reactome.org/PathwayBrowser/#/R-DME-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Drosophila melanogaster 57783 R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Drosophila melanogaster 57783 R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Drosophila melanogaster 57783 R-DME-70938 https://reactome.org/PathwayBrowser/#/R-DME-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Drosophila melanogaster 57783 R-DME-71200 https://reactome.org/PathwayBrowser/#/R-DME-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Drosophila melanogaster 57783 R-DME-71299 https://reactome.org/PathwayBrowser/#/R-DME-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Drosophila melanogaster 57783 R-DME-73585 https://reactome.org/PathwayBrowser/#/R-DME-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Drosophila melanogaster 57783 R-DME-73616 https://reactome.org/PathwayBrowser/#/R-DME-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Drosophila melanogaster 57783 R-DME-74872 https://reactome.org/PathwayBrowser/#/R-DME-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 57783 R-DME-75872 https://reactome.org/PathwayBrowser/#/R-DME-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Drosophila melanogaster 57783 R-DME-75883 https://reactome.org/PathwayBrowser/#/R-DME-75883 DHRS7B reduces GO3P to HXDG3P IEA Drosophila melanogaster 57783 R-DME-8862137 https://reactome.org/PathwayBrowser/#/R-DME-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Drosophila melanogaster 57783 R-DME-8952873 https://reactome.org/PathwayBrowser/#/R-DME-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Drosophila melanogaster 57783 R-DME-9012036 https://reactome.org/PathwayBrowser/#/R-DME-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 57783 R-DME-9012349 https://reactome.org/PathwayBrowser/#/R-DME-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 57783 R-DME-9027043 https://reactome.org/PathwayBrowser/#/R-DME-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Drosophila melanogaster 57783 R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 57783 R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 57783 R-DME-9705714 https://reactome.org/PathwayBrowser/#/R-DME-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Drosophila melanogaster 57783 R-DME-9709098 https://reactome.org/PathwayBrowser/#/R-DME-9709098 DHFR dimer reduces FOLA to DHF IEA Drosophila melanogaster 57783 R-DME-9753285 https://reactome.org/PathwayBrowser/#/R-DME-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Drosophila melanogaster 57783 R-DME-975629 https://reactome.org/PathwayBrowser/#/R-DME-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 57783 R-DME-9758682 https://reactome.org/PathwayBrowser/#/R-DME-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Drosophila melanogaster 57783 R-DME-9759259 https://reactome.org/PathwayBrowser/#/R-DME-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Drosophila melanogaster 57783 R-DRE-1222376 https://reactome.org/PathwayBrowser/#/R-DRE-1222376 NOX2 generates superoxide from oxygen IEA Danio rerio 57783 R-DRE-1475414 https://reactome.org/PathwayBrowser/#/R-DRE-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Danio rerio 57783 R-DRE-1497869 https://reactome.org/PathwayBrowser/#/R-DRE-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Danio rerio 57783 R-DRE-156526 https://reactome.org/PathwayBrowser/#/R-DRE-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Danio rerio 57783 R-DRE-1655453 https://reactome.org/PathwayBrowser/#/R-DRE-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Danio rerio 57783 R-DRE-189384 https://reactome.org/PathwayBrowser/#/R-DRE-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Danio rerio 57783 R-DRE-189398 https://reactome.org/PathwayBrowser/#/R-DRE-189398 HMOX1 dimer, HMOX2 cleave heme IEA Danio rerio 57783 R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 57783 R-DRE-191352 https://reactome.org/PathwayBrowser/#/R-DRE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Danio rerio 57783 R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 57783 R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 57783 R-DRE-192157 https://reactome.org/PathwayBrowser/#/R-DRE-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Danio rerio 57783 R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 57783 R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 57783 R-DRE-193064 https://reactome.org/PathwayBrowser/#/R-DRE-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Danio rerio 57783 R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 57783 R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 57783 R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 57783 R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 57783 R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 57783 R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 57783 R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 57783 R-DRE-193709 https://reactome.org/PathwayBrowser/#/R-DRE-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Danio rerio 57783 R-DRE-193845 https://reactome.org/PathwayBrowser/#/R-DRE-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Danio rerio 57783 R-DRE-194023 https://reactome.org/PathwayBrowser/#/R-DRE-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Danio rerio 57783 R-DRE-194632 https://reactome.org/PathwayBrowser/#/R-DRE-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Danio rerio 57783 R-DRE-194641 https://reactome.org/PathwayBrowser/#/R-DRE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 57783 R-DRE-194669 https://reactome.org/PathwayBrowser/#/R-DRE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 57783 R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 57783 R-DRE-194689 https://reactome.org/PathwayBrowser/#/R-DRE-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Danio rerio 57783 R-DRE-194698 https://reactome.org/PathwayBrowser/#/R-DRE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Danio rerio 57783 R-DRE-195664 https://reactome.org/PathwayBrowser/#/R-DRE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Danio rerio 57783 R-DRE-196060 https://reactome.org/PathwayBrowser/#/R-DRE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Danio rerio 57783 R-DRE-196402 https://reactome.org/PathwayBrowser/#/R-DRE-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Danio rerio 57783 R-DRE-196417 https://reactome.org/PathwayBrowser/#/R-DRE-196417 Reduction of desmosterol to cholesterol IEA Danio rerio 57783 R-DRE-197963 https://reactome.org/PathwayBrowser/#/R-DRE-197963 DHFR2 reduces FOLA to DHF IEA Danio rerio 57783 R-DRE-197972 https://reactome.org/PathwayBrowser/#/R-DRE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Danio rerio 57783 R-DRE-200644 https://reactome.org/PathwayBrowser/#/R-DRE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Danio rerio 57783 R-DRE-200676 https://reactome.org/PathwayBrowser/#/R-DRE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Danio rerio 57783 R-DRE-200718 https://reactome.org/PathwayBrowser/#/R-DRE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Danio rerio 57783 R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 57783 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 57783 R-DRE-211873 https://reactome.org/PathwayBrowser/#/R-DRE-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Danio rerio 57783 R-DRE-211923 https://reactome.org/PathwayBrowser/#/R-DRE-211923 CYP26C1 4-hydroxylates 9cRA IEA Danio rerio 57783 R-DRE-211950 https://reactome.org/PathwayBrowser/#/R-DRE-211950 CYP24A1 24-hydroxylates CTL IEA Danio rerio 57783 R-DRE-211951 https://reactome.org/PathwayBrowser/#/R-DRE-211951 CYP1B1 4-hydroxylates EST17b IEA Danio rerio 57783 R-DRE-2161651 https://reactome.org/PathwayBrowser/#/R-DRE-2161651 PGE2 is converted to PGF2a by CBR1 IEA Danio rerio 57783 R-DRE-2161745 https://reactome.org/PathwayBrowser/#/R-DRE-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Danio rerio 57783 R-DRE-2161792 https://reactome.org/PathwayBrowser/#/R-DRE-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Danio rerio 57783 R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio 57783 R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Danio rerio 57783 R-DRE-2161951 https://reactome.org/PathwayBrowser/#/R-DRE-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Danio rerio 57783 R-DRE-2395517 https://reactome.org/PathwayBrowser/#/R-DRE-2395517 NADPH transfers electrons to FDXR IEA Danio rerio 57783 R-DRE-2464822 https://reactome.org/PathwayBrowser/#/R-DRE-2464822 RDH12 reduces atRAL to atROL IEA Danio rerio 57783 R-DRE-2465940 https://reactome.org/PathwayBrowser/#/R-DRE-2465940 atRAL is reduced to atROL IEA Danio rerio 57783 R-DRE-2855252 https://reactome.org/PathwayBrowser/#/R-DRE-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Danio rerio 57783 R-DRE-3149519 https://reactome.org/PathwayBrowser/#/R-DRE-3149519 MMACHC decyanates CNCbl IEA Danio rerio 57783 R-DRE-389540 https://reactome.org/PathwayBrowser/#/R-DRE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 57783 R-DRE-390438 https://reactome.org/PathwayBrowser/#/R-DRE-390438 FAR2 reduces PalmCoA to HXOL IEA Danio rerio 57783 R-DRE-418436 https://reactome.org/PathwayBrowser/#/R-DRE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Danio rerio 57783 R-DRE-4419979 https://reactome.org/PathwayBrowser/#/R-DRE-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Danio rerio 57783 R-DRE-450971 https://reactome.org/PathwayBrowser/#/R-DRE-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Danio rerio 57783 R-DRE-450984 https://reactome.org/PathwayBrowser/#/R-DRE-450984 IDH2 dimer decarboxylates isocitrate IEA Danio rerio 57783 R-DRE-469659 https://reactome.org/PathwayBrowser/#/R-DRE-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Danio rerio 57783 R-DRE-514604 https://reactome.org/PathwayBrowser/#/R-DRE-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Danio rerio 57783 R-DRE-5218841 https://reactome.org/PathwayBrowser/#/R-DRE-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Danio rerio 57783 R-DRE-5340226 https://reactome.org/PathwayBrowser/#/R-DRE-5340226 CYGB dioxygenates NO IEA Danio rerio 57783 R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 57783 R-DRE-5419165 https://reactome.org/PathwayBrowser/#/R-DRE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Danio rerio 57783 R-DRE-5423637 https://reactome.org/PathwayBrowser/#/R-DRE-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Danio rerio 57783 R-DRE-5423647 https://reactome.org/PathwayBrowser/#/R-DRE-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Danio rerio 57783 R-DRE-5423664 https://reactome.org/PathwayBrowser/#/R-DRE-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Danio rerio 57783 R-DRE-5423672 https://reactome.org/PathwayBrowser/#/R-DRE-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Danio rerio 57783 R-DRE-5423678 https://reactome.org/PathwayBrowser/#/R-DRE-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Danio rerio 57783 R-DRE-548818 https://reactome.org/PathwayBrowser/#/R-DRE-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Danio rerio 57783 R-DRE-5602295 https://reactome.org/PathwayBrowser/#/R-DRE-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Danio rerio 57783 R-DRE-5652172 https://reactome.org/PathwayBrowser/#/R-DRE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Danio rerio 57783 R-DRE-5661240 https://reactome.org/PathwayBrowser/#/R-DRE-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Danio rerio 57783 R-DRE-5661256 https://reactome.org/PathwayBrowser/#/R-DRE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Danio rerio 57783 R-DRE-5668629 https://reactome.org/PathwayBrowser/#/R-DRE-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Danio rerio 57783 R-DRE-5668718 https://reactome.org/PathwayBrowser/#/R-DRE-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 57783 R-DRE-5668731 https://reactome.org/PathwayBrowser/#/R-DRE-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 57783 R-DRE-5692232 https://reactome.org/PathwayBrowser/#/R-DRE-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Danio rerio 57783 R-DRE-5692283 https://reactome.org/PathwayBrowser/#/R-DRE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Danio rerio 57783 R-DRE-5696822 https://reactome.org/PathwayBrowser/#/R-DRE-5696822 AKR1B15 reduces EST17b to E1 IEA Danio rerio 57783 R-DRE-6783955 https://reactome.org/PathwayBrowser/#/R-DRE-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 57783 R-DRE-6786239 https://reactome.org/PathwayBrowser/#/R-DRE-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Danio rerio 57783 R-DRE-6787642 https://reactome.org/PathwayBrowser/#/R-DRE-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Danio rerio 57783 R-DRE-6789092 https://reactome.org/PathwayBrowser/#/R-DRE-6789092 NOX2 generates superoxide anion from oxygen IEA Danio rerio 57783 R-DRE-6806967 https://reactome.org/PathwayBrowser/#/R-DRE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Danio rerio 57783 R-DRE-6807053 https://reactome.org/PathwayBrowser/#/R-DRE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Danio rerio 57783 R-DRE-6807055 https://reactome.org/PathwayBrowser/#/R-DRE-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Danio rerio 57783 R-DRE-6807064 https://reactome.org/PathwayBrowser/#/R-DRE-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Danio rerio 57783 R-DRE-6808496 https://reactome.org/PathwayBrowser/#/R-DRE-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Danio rerio 57783 R-DRE-6810594 https://reactome.org/PathwayBrowser/#/R-DRE-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Danio rerio 57783 R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Danio rerio 57783 R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Danio rerio 57783 R-DRE-70938 https://reactome.org/PathwayBrowser/#/R-DRE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Danio rerio 57783 R-DRE-71200 https://reactome.org/PathwayBrowser/#/R-DRE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Danio rerio 57783 R-DRE-71299 https://reactome.org/PathwayBrowser/#/R-DRE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Danio rerio 57783 R-DRE-73585 https://reactome.org/PathwayBrowser/#/R-DRE-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Danio rerio 57783 R-DRE-73616 https://reactome.org/PathwayBrowser/#/R-DRE-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Danio rerio 57783 R-DRE-74872 https://reactome.org/PathwayBrowser/#/R-DRE-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Danio rerio 57783 R-DRE-75872 https://reactome.org/PathwayBrowser/#/R-DRE-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Danio rerio 57783 R-DRE-75883 https://reactome.org/PathwayBrowser/#/R-DRE-75883 DHRS7B reduces GO3P to HXDG3P IEA Danio rerio 57783 R-DRE-8862152 https://reactome.org/PathwayBrowser/#/R-DRE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Danio rerio 57783 R-DRE-8865107 https://reactome.org/PathwayBrowser/#/R-DRE-8865107 MICAL1 produces NADP+, H2O2 IEA Danio rerio 57783 R-DRE-8937419 https://reactome.org/PathwayBrowser/#/R-DRE-8937419 CBR3 reduces DOX to DOXOL IEA Danio rerio 57783 R-DRE-8952873 https://reactome.org/PathwayBrowser/#/R-DRE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Danio rerio 57783 R-DRE-9012036 https://reactome.org/PathwayBrowser/#/R-DRE-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Danio rerio 57783 R-DRE-9012349 https://reactome.org/PathwayBrowser/#/R-DRE-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Danio rerio 57783 R-DRE-9020255 https://reactome.org/PathwayBrowser/#/R-DRE-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Danio rerio 57783 R-DRE-9020256 https://reactome.org/PathwayBrowser/#/R-DRE-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Danio rerio 57783 R-DRE-9020262 https://reactome.org/PathwayBrowser/#/R-DRE-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Danio rerio 57783 R-DRE-9020277 https://reactome.org/PathwayBrowser/#/R-DRE-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Danio rerio 57783 R-DRE-9020278 https://reactome.org/PathwayBrowser/#/R-DRE-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Danio rerio 57783 R-DRE-9024881 https://reactome.org/PathwayBrowser/#/R-DRE-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Danio rerio 57783 R-DRE-9024983 https://reactome.org/PathwayBrowser/#/R-DRE-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Danio rerio 57783 R-DRE-9025995 https://reactome.org/PathwayBrowser/#/R-DRE-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Danio rerio 57783 R-DRE-9025999 https://reactome.org/PathwayBrowser/#/R-DRE-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Danio rerio 57783 R-DRE-9026007 https://reactome.org/PathwayBrowser/#/R-DRE-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Danio rerio 57783 R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio 57783 R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 57783 R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 57783 R-DRE-9037761 https://reactome.org/PathwayBrowser/#/R-DRE-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Danio rerio 57783 R-DRE-9705713 https://reactome.org/PathwayBrowser/#/R-DRE-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Danio rerio 57783 R-DRE-9705714 https://reactome.org/PathwayBrowser/#/R-DRE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Danio rerio 57783 R-DRE-9709098 https://reactome.org/PathwayBrowser/#/R-DRE-9709098 DHFR dimer reduces FOLA to DHF IEA Danio rerio 57783 R-DRE-9753285 https://reactome.org/PathwayBrowser/#/R-DRE-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Danio rerio 57783 R-DRE-9755937 https://reactome.org/PathwayBrowser/#/R-DRE-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Danio rerio 57783 R-DRE-9756138 https://reactome.org/PathwayBrowser/#/R-DRE-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Danio rerio 57783 R-DRE-9756162 https://reactome.org/PathwayBrowser/#/R-DRE-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Danio rerio 57783 R-DRE-9756169 https://reactome.org/PathwayBrowser/#/R-DRE-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Danio rerio 57783 R-DRE-9756180 https://reactome.org/PathwayBrowser/#/R-DRE-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Danio rerio 57783 R-DRE-975629 https://reactome.org/PathwayBrowser/#/R-DRE-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Danio rerio 57783 R-DRE-9757706 https://reactome.org/PathwayBrowser/#/R-DRE-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Danio rerio 57783 R-DRE-9759259 https://reactome.org/PathwayBrowser/#/R-DRE-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Danio rerio 57783 R-ECO-1222667 https://reactome.org/PathwayBrowser/#/R-ECO-1222667 Iron is reduced and separates from enterobactin TAS Escherichia coli 57783 R-GGA-1222376 https://reactome.org/PathwayBrowser/#/R-GGA-1222376 NOX2 generates superoxide from oxygen IEA Gallus gallus 57783 R-GGA-1475414 https://reactome.org/PathwayBrowser/#/R-GGA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Gallus gallus 57783 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 57783 R-GGA-1497869 https://reactome.org/PathwayBrowser/#/R-GGA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Gallus gallus 57783 R-GGA-156526 https://reactome.org/PathwayBrowser/#/R-GGA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Gallus gallus 57783 R-GGA-189384 https://reactome.org/PathwayBrowser/#/R-GGA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Gallus gallus 57783 R-GGA-189398 https://reactome.org/PathwayBrowser/#/R-GGA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Gallus gallus 57783 R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 57783 R-GGA-191352 https://reactome.org/PathwayBrowser/#/R-GGA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Gallus gallus 57783 R-GGA-191402 https://reactome.org/PathwayBrowser/#/R-GGA-191402 Reduction of presqualene diphosphate to form squalene IEA Gallus gallus 57783 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 57783 R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 57783 R-GGA-192033 https://reactome.org/PathwayBrowser/#/R-GGA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Gallus gallus 57783 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 57783 R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 57783 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 57783 R-GGA-192067 https://reactome.org/PathwayBrowser/#/R-GGA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Gallus gallus 57783 R-GGA-192178 https://reactome.org/PathwayBrowser/#/R-GGA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Gallus gallus 57783 R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 57783 R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 57783 R-GGA-193064 https://reactome.org/PathwayBrowser/#/R-GGA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Gallus gallus 57783 R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 57783 R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 57783 R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 57783 R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 57783 R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 57783 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 57783 R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 57783 R-GGA-193746 https://reactome.org/PathwayBrowser/#/R-GGA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Gallus gallus 57783 R-GGA-193755 https://reactome.org/PathwayBrowser/#/R-GGA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Gallus gallus 57783 R-GGA-193821 https://reactome.org/PathwayBrowser/#/R-GGA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Gallus gallus 57783 R-GGA-193824 https://reactome.org/PathwayBrowser/#/R-GGA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Gallus gallus 57783 R-GGA-193964 https://reactome.org/PathwayBrowser/#/R-GGA-193964 CYP21A2 21-hydroxylates PROG IEA Gallus gallus 57783 R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 57783 R-GGA-194023 https://reactome.org/PathwayBrowser/#/R-GGA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Gallus gallus 57783 R-GGA-194632 https://reactome.org/PathwayBrowser/#/R-GGA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Gallus gallus 57783 R-GGA-194641 https://reactome.org/PathwayBrowser/#/R-GGA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 57783 R-GGA-194669 https://reactome.org/PathwayBrowser/#/R-GGA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 57783 R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 57783 R-GGA-194689 https://reactome.org/PathwayBrowser/#/R-GGA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 57783 R-GGA-195664 https://reactome.org/PathwayBrowser/#/R-GGA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Gallus gallus 57783 R-GGA-196060 https://reactome.org/PathwayBrowser/#/R-GGA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Gallus gallus 57783 R-GGA-196402 https://reactome.org/PathwayBrowser/#/R-GGA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Gallus gallus 57783 R-GGA-196417 https://reactome.org/PathwayBrowser/#/R-GGA-196417 Reduction of desmosterol to cholesterol IEA Gallus gallus 57783 R-GGA-197963 https://reactome.org/PathwayBrowser/#/R-GGA-197963 DHFR2 reduces FOLA to DHF IEA Gallus gallus 57783 R-GGA-197972 https://reactome.org/PathwayBrowser/#/R-GGA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Gallus gallus 57783 R-GGA-200644 https://reactome.org/PathwayBrowser/#/R-GGA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Gallus gallus 57783 R-GGA-200676 https://reactome.org/PathwayBrowser/#/R-GGA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Gallus gallus 57783 R-GGA-200718 https://reactome.org/PathwayBrowser/#/R-GGA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Gallus gallus 57783 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 57783 R-GGA-209772 https://reactome.org/PathwayBrowser/#/R-GGA-209772 Thyroxine is deiodinated to triiodothyronine IEA Gallus gallus 57783 R-GGA-209845 https://reactome.org/PathwayBrowser/#/R-GGA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Gallus gallus 57783 R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus 57783 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 57783 R-GGA-2161651 https://reactome.org/PathwayBrowser/#/R-GGA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Gallus gallus 57783 R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus 57783 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Gallus gallus 57783 R-GGA-2161951 https://reactome.org/PathwayBrowser/#/R-GGA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Gallus gallus 57783 R-GGA-2395517 https://reactome.org/PathwayBrowser/#/R-GGA-2395517 NADPH transfers electrons to FDXR IEA Gallus gallus 57783 R-GGA-2464822 https://reactome.org/PathwayBrowser/#/R-GGA-2464822 RDH12 reduces atRAL to atROL IEA Gallus gallus 57783 R-GGA-2465940 https://reactome.org/PathwayBrowser/#/R-GGA-2465940 atRAL is reduced to atROL IEA Gallus gallus 57783 R-GGA-2855252 https://reactome.org/PathwayBrowser/#/R-GGA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Gallus gallus 57783 R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus 57783 R-GGA-3149519 https://reactome.org/PathwayBrowser/#/R-GGA-3149519 MMACHC decyanates CNCbl IEA Gallus gallus 57783 R-GGA-3323050 https://reactome.org/PathwayBrowser/#/R-GGA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Gallus gallus 57783 R-GGA-3323079 https://reactome.org/PathwayBrowser/#/R-GGA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 57783 R-GGA-389540 https://reactome.org/PathwayBrowser/#/R-GGA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 57783 R-GGA-390425 https://reactome.org/PathwayBrowser/#/R-GGA-390425 FAR1 reduces PalmCoA to HXOL IEA Gallus gallus 57783 R-GGA-390438 https://reactome.org/PathwayBrowser/#/R-GGA-390438 FAR2 reduces PalmCoA to HXOL IEA Gallus gallus 57783 R-GGA-418436 https://reactome.org/PathwayBrowser/#/R-GGA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Gallus gallus 57783 R-GGA-433576 https://reactome.org/PathwayBrowser/#/R-GGA-433576 3-dehydrosphinganine + NADPH + H+ => sphinganine + NADP+ IEA Gallus gallus 57783 R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 57783 R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 57783 R-GGA-4419979 https://reactome.org/PathwayBrowser/#/R-GGA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Gallus gallus 57783 R-GGA-450971 https://reactome.org/PathwayBrowser/#/R-GGA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Gallus gallus 57783 R-GGA-450984 https://reactome.org/PathwayBrowser/#/R-GGA-450984 IDH2 dimer decarboxylates isocitrate IEA Gallus gallus 57783 R-GGA-469659 https://reactome.org/PathwayBrowser/#/R-GGA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Gallus gallus 57783 R-GGA-508040 https://reactome.org/PathwayBrowser/#/R-GGA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Gallus gallus 57783 R-GGA-514604 https://reactome.org/PathwayBrowser/#/R-GGA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Gallus gallus 57783 R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus 57783 R-GGA-5263614 https://reactome.org/PathwayBrowser/#/R-GGA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Gallus gallus 57783 R-GGA-5263616 https://reactome.org/PathwayBrowser/#/R-GGA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Gallus gallus 57783 R-GGA-5340226 https://reactome.org/PathwayBrowser/#/R-GGA-5340226 CYGB dioxygenates NO IEA Gallus gallus 57783 R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 57783 R-GGA-5419165 https://reactome.org/PathwayBrowser/#/R-GGA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Gallus gallus 57783 R-GGA-5423637 https://reactome.org/PathwayBrowser/#/R-GGA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Gallus gallus 57783 R-GGA-5423664 https://reactome.org/PathwayBrowser/#/R-GGA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Gallus gallus 57783 R-GGA-5423672 https://reactome.org/PathwayBrowser/#/R-GGA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Gallus gallus 57783 R-GGA-5423678 https://reactome.org/PathwayBrowser/#/R-GGA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Gallus gallus 57783 R-GGA-548818 https://reactome.org/PathwayBrowser/#/R-GGA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Gallus gallus 57783 R-GGA-548831 https://reactome.org/PathwayBrowser/#/R-GGA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Gallus gallus 57783 R-GGA-5652172 https://reactome.org/PathwayBrowser/#/R-GGA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Gallus gallus 57783 R-GGA-5661240 https://reactome.org/PathwayBrowser/#/R-GGA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Gallus gallus 57783 R-GGA-5661256 https://reactome.org/PathwayBrowser/#/R-GGA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Gallus gallus 57783 R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus 57783 R-GGA-5668718 https://reactome.org/PathwayBrowser/#/R-GGA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 57783 R-GGA-5668731 https://reactome.org/PathwayBrowser/#/R-GGA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 57783 R-GGA-5692232 https://reactome.org/PathwayBrowser/#/R-GGA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Gallus gallus 57783 R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus 57783 R-GGA-5693390 https://reactome.org/PathwayBrowser/#/R-GGA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Gallus gallus 57783 R-GGA-5696822 https://reactome.org/PathwayBrowser/#/R-GGA-5696822 AKR1B15 reduces EST17b to E1 IEA Gallus gallus 57783 R-GGA-6783955 https://reactome.org/PathwayBrowser/#/R-GGA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 57783 R-GGA-6786239 https://reactome.org/PathwayBrowser/#/R-GGA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Gallus gallus 57783 R-GGA-6787642 https://reactome.org/PathwayBrowser/#/R-GGA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Gallus gallus 57783 R-GGA-6789092 https://reactome.org/PathwayBrowser/#/R-GGA-6789092 NOX2 generates superoxide anion from oxygen IEA Gallus gallus 57783 R-GGA-6799722 https://reactome.org/PathwayBrowser/#/R-GGA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Gallus gallus 57783 R-GGA-6806967 https://reactome.org/PathwayBrowser/#/R-GGA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Gallus gallus 57783 R-GGA-6807053 https://reactome.org/PathwayBrowser/#/R-GGA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Gallus gallus 57783 R-GGA-6807055 https://reactome.org/PathwayBrowser/#/R-GGA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Gallus gallus 57783 R-GGA-6807064 https://reactome.org/PathwayBrowser/#/R-GGA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Gallus gallus 57783 R-GGA-6807557 https://reactome.org/PathwayBrowser/#/R-GGA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Gallus gallus 57783 R-GGA-6808487 https://reactome.org/PathwayBrowser/#/R-GGA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Gallus gallus 57783 R-GGA-70577 https://reactome.org/PathwayBrowser/#/R-GGA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Gallus gallus 57783 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Gallus gallus 57783 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Gallus gallus 57783 R-GGA-70938 https://reactome.org/PathwayBrowser/#/R-GGA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Gallus gallus 57783 R-GGA-71200 https://reactome.org/PathwayBrowser/#/R-GGA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Gallus gallus 57783 R-GGA-71299 https://reactome.org/PathwayBrowser/#/R-GGA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Gallus gallus 57783 R-GGA-71682 https://reactome.org/PathwayBrowser/#/R-GGA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 57783 R-GGA-73585 https://reactome.org/PathwayBrowser/#/R-GGA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Gallus gallus 57783 R-GGA-73616 https://reactome.org/PathwayBrowser/#/R-GGA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Gallus gallus 57783 R-GGA-73646 https://reactome.org/PathwayBrowser/#/R-GGA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Gallus gallus 57783 R-GGA-74872 https://reactome.org/PathwayBrowser/#/R-GGA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Gallus gallus 57783 R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Gallus gallus 57783 R-GGA-75883 https://reactome.org/PathwayBrowser/#/R-GGA-75883 DHRS7B reduces GO3P to HXDG3P IEA Gallus gallus 57783 R-GGA-8862137 https://reactome.org/PathwayBrowser/#/R-GGA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Gallus gallus 57783 R-GGA-8865107 https://reactome.org/PathwayBrowser/#/R-GGA-8865107 MICAL1 produces NADP+, H2O2 IEA Gallus gallus 57783 R-GGA-8937419 https://reactome.org/PathwayBrowser/#/R-GGA-8937419 CBR3 reduces DOX to DOXOL IEA Gallus gallus 57783 R-GGA-8952873 https://reactome.org/PathwayBrowser/#/R-GGA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Gallus gallus 57783 R-GGA-9012036 https://reactome.org/PathwayBrowser/#/R-GGA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Gallus gallus 57783 R-GGA-9012349 https://reactome.org/PathwayBrowser/#/R-GGA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Gallus gallus 57783 R-GGA-9020255 https://reactome.org/PathwayBrowser/#/R-GGA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Gallus gallus 57783 R-GGA-9020256 https://reactome.org/PathwayBrowser/#/R-GGA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Gallus gallus 57783 R-GGA-9020277 https://reactome.org/PathwayBrowser/#/R-GGA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Gallus gallus 57783 R-GGA-9020278 https://reactome.org/PathwayBrowser/#/R-GGA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Gallus gallus 57783 R-GGA-9025995 https://reactome.org/PathwayBrowser/#/R-GGA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Gallus gallus 57783 R-GGA-9025999 https://reactome.org/PathwayBrowser/#/R-GGA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Gallus gallus 57783 R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus 57783 R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 57783 R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 57783 R-GGA-9037761 https://reactome.org/PathwayBrowser/#/R-GGA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Gallus gallus 57783 R-GGA-917811 https://reactome.org/PathwayBrowser/#/R-GGA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Gallus gallus 57783 R-GGA-9705713 https://reactome.org/PathwayBrowser/#/R-GGA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Gallus gallus 57783 R-GGA-9705714 https://reactome.org/PathwayBrowser/#/R-GGA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Gallus gallus 57783 R-GGA-9709098 https://reactome.org/PathwayBrowser/#/R-GGA-9709098 DHFR dimer reduces FOLA to DHF IEA Gallus gallus 57783 R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus 57783 R-GGA-9755937 https://reactome.org/PathwayBrowser/#/R-GGA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Gallus gallus 57783 R-GGA-9756138 https://reactome.org/PathwayBrowser/#/R-GGA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Gallus gallus 57783 R-GGA-9756162 https://reactome.org/PathwayBrowser/#/R-GGA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Gallus gallus 57783 R-GGA-9756169 https://reactome.org/PathwayBrowser/#/R-GGA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Gallus gallus 57783 R-GGA-9756180 https://reactome.org/PathwayBrowser/#/R-GGA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Gallus gallus 57783 R-GGA-975629 https://reactome.org/PathwayBrowser/#/R-GGA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Gallus gallus 57783 R-GGA-9757706 https://reactome.org/PathwayBrowser/#/R-GGA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Gallus gallus 57783 R-GGA-9759259 https://reactome.org/PathwayBrowser/#/R-GGA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Gallus gallus 57783 R-HSA-1222376 https://reactome.org/PathwayBrowser/#/R-HSA-1222376 NOX2 generates superoxide from oxygen TAS Homo sapiens 57783 R-HSA-1222399 https://reactome.org/PathwayBrowser/#/R-HSA-1222399 Iron is reduced and separates from mycobactin IEA Homo sapiens 57783 R-HSA-1222485 https://reactome.org/PathwayBrowser/#/R-HSA-1222485 TrxB reactivates TrxA TAS Homo sapiens 57783 R-HSA-1475414 https://reactome.org/PathwayBrowser/#/R-HSA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) TAS Homo sapiens 57783 R-HSA-1497794 https://reactome.org/PathwayBrowser/#/R-HSA-1497794 Salvage - BH2 is reduced to BH4 by DHFR IEA Homo sapiens 57783 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 57783 R-HSA-1497869 https://reactome.org/PathwayBrowser/#/R-HSA-1497869 Salvage - Sepiapterin is reduced to BH2 TAS Homo sapiens 57783 R-HSA-156526 https://reactome.org/PathwayBrowser/#/R-HSA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO TAS Homo sapiens 57783 R-HSA-1655453 https://reactome.org/PathwayBrowser/#/R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU TAS Homo sapiens 57783 R-HSA-189384 https://reactome.org/PathwayBrowser/#/R-HSA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL TAS Homo sapiens 57783 R-HSA-189398 https://reactome.org/PathwayBrowser/#/R-HSA-189398 HMOX1 dimer, HMOX2 cleave heme TAS Homo sapiens 57783 R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 57783 R-HSA-191352 https://reactome.org/PathwayBrowser/#/R-HSA-191352 HMGCR dimer reduces bHMG-CoA to MVA TAS Homo sapiens 57783 R-HSA-191402 https://reactome.org/PathwayBrowser/#/R-HSA-191402 Reduction of presqualene diphosphate to form squalene TAS Homo sapiens 57783 R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 57783 R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 57783 R-HSA-191999 https://reactome.org/PathwayBrowser/#/R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol TAS Homo sapiens 57783 R-HSA-192033 https://reactome.org/PathwayBrowser/#/R-HSA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one TAS Homo sapiens 57783 R-HSA-192036 https://reactome.org/PathwayBrowser/#/R-HSA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol TAS Homo sapiens 57783 R-HSA-192042 https://reactome.org/PathwayBrowser/#/R-HSA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 57783 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 57783 R-HSA-192054 https://reactome.org/PathwayBrowser/#/R-HSA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) TAS Homo sapiens 57783 R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 57783 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 57783 R-HSA-192067 https://reactome.org/PathwayBrowser/#/R-HSA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one TAS Homo sapiens 57783 R-HSA-192123 https://reactome.org/PathwayBrowser/#/R-HSA-192123 CYP27A1 27-hydroxylates CHOL TAS Homo sapiens 57783 R-HSA-192157 https://reactome.org/PathwayBrowser/#/R-HSA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE TAS Homo sapiens 57783 R-HSA-192160 https://reactome.org/PathwayBrowser/#/R-HSA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol TAS Homo sapiens 57783 R-HSA-192178 https://reactome.org/PathwayBrowser/#/R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL TAS Homo sapiens 57783 R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 57783 R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 57783 R-HSA-193064 https://reactome.org/PathwayBrowser/#/R-HSA-193064 HSD17B3-like proteins reducde ANDST to TEST TAS Homo sapiens 57783 R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 57783 R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 57783 R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 57783 R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 57783 R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 57783 R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 57783 R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 57783 R-HSA-193393 https://reactome.org/PathwayBrowser/#/R-HSA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol TAS Homo sapiens 57783 R-HSA-193460 https://reactome.org/PathwayBrowser/#/R-HSA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) TAS Homo sapiens 57783 R-HSA-193497 https://reactome.org/PathwayBrowser/#/R-HSA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al TAS Homo sapiens 57783 R-HSA-193709 https://reactome.org/PathwayBrowser/#/R-HSA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL TAS Homo sapiens 57783 R-HSA-193713 https://reactome.org/PathwayBrowser/#/R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) TAS Homo sapiens 57783 R-HSA-193719 https://reactome.org/PathwayBrowser/#/R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 57783 R-HSA-193737 https://reactome.org/PathwayBrowser/#/R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) TAS Homo sapiens 57783 R-HSA-193746 https://reactome.org/PathwayBrowser/#/R-HSA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one TAS Homo sapiens 57783 R-HSA-193755 https://reactome.org/PathwayBrowser/#/R-HSA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one TAS Homo sapiens 57783 R-HSA-193758 https://reactome.org/PathwayBrowser/#/R-HSA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol TAS Homo sapiens 57783 R-HSA-193780 https://reactome.org/PathwayBrowser/#/R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al TAS Homo sapiens 57783 R-HSA-193781 https://reactome.org/PathwayBrowser/#/R-HSA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol TAS Homo sapiens 57783 R-HSA-193787 https://reactome.org/PathwayBrowser/#/R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol TAS Homo sapiens 57783 R-HSA-193792 https://reactome.org/PathwayBrowser/#/R-HSA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 57783 R-HSA-193800 https://reactome.org/PathwayBrowser/#/R-HSA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol TAS Homo sapiens 57783 R-HSA-193821 https://reactome.org/PathwayBrowser/#/R-HSA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one TAS Homo sapiens 57783 R-HSA-193824 https://reactome.org/PathwayBrowser/#/R-HSA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one TAS Homo sapiens 57783 R-HSA-193841 https://reactome.org/PathwayBrowser/#/R-HSA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol TAS Homo sapiens 57783 R-HSA-193845 https://reactome.org/PathwayBrowser/#/R-HSA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE TAS Homo sapiens 57783 R-HSA-193964 https://reactome.org/PathwayBrowser/#/R-HSA-193964 CYP21A2 21-hydroxylates PROG TAS Homo sapiens 57783 R-HSA-193965 https://reactome.org/PathwayBrowser/#/R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO TAS Homo sapiens 57783 R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 57783 R-HSA-193995 https://reactome.org/PathwayBrowser/#/R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST TAS Homo sapiens 57783 R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 57783 R-HSA-194017 https://reactome.org/PathwayBrowser/#/R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST TAS Homo sapiens 57783 R-HSA-194023 https://reactome.org/PathwayBrowser/#/R-HSA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR TAS Homo sapiens 57783 R-HSA-194632 https://reactome.org/PathwayBrowser/#/R-HSA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) TAS Homo sapiens 57783 R-HSA-194641 https://reactome.org/PathwayBrowser/#/R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 57783 R-HSA-194669 https://reactome.org/PathwayBrowser/#/R-HSA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 57783 R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 57783 R-HSA-194689 https://reactome.org/PathwayBrowser/#/R-HSA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 57783 R-HSA-194698 https://reactome.org/PathwayBrowser/#/R-HSA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] TAS Homo sapiens 57783 R-HSA-195664 https://reactome.org/PathwayBrowser/#/R-HSA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol TAS Homo sapiens 57783 R-HSA-196060 https://reactome.org/PathwayBrowser/#/R-HSA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol TAS Homo sapiens 57783 R-HSA-196402 https://reactome.org/PathwayBrowser/#/R-HSA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol TAS Homo sapiens 57783 R-HSA-196417 https://reactome.org/PathwayBrowser/#/R-HSA-196417 Reduction of desmosterol to cholesterol TAS Homo sapiens 57783 R-HSA-197963 https://reactome.org/PathwayBrowser/#/R-HSA-197963 DHFR2 reduces FOLA to DHF TAS Homo sapiens 57783 R-HSA-197972 https://reactome.org/PathwayBrowser/#/R-HSA-197972 DHF is reduced to tetrahydrofolate (THF) TAS Homo sapiens 57783 R-HSA-200644 https://reactome.org/PathwayBrowser/#/R-HSA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ TAS Homo sapiens 57783 R-HSA-200676 https://reactome.org/PathwayBrowser/#/R-HSA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG TAS Homo sapiens 57783 R-HSA-200718 https://reactome.org/PathwayBrowser/#/R-HSA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG TAS Homo sapiens 57783 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 57783 R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 57783 R-HSA-209772 https://reactome.org/PathwayBrowser/#/R-HSA-209772 Thyroxine is deiodinated to triiodothyronine TAS Homo sapiens 57783 R-HSA-209845 https://reactome.org/PathwayBrowser/#/R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D TAS Homo sapiens 57783 R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 57783 R-HSA-211873 https://reactome.org/PathwayBrowser/#/R-HSA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 TAS Homo sapiens 57783 R-HSA-211923 https://reactome.org/PathwayBrowser/#/R-HSA-211923 CYP26C1 4-hydroxylates 9cRA TAS Homo sapiens 57783 R-HSA-211950 https://reactome.org/PathwayBrowser/#/R-HSA-211950 CYP24A1 24-hydroxylates CTL TAS Homo sapiens 57783 R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 57783 R-HSA-2161549 https://reactome.org/PathwayBrowser/#/R-HSA-2161549 PGH2 is reduced to PGF2a by AKR1C3 TAS Homo sapiens 57783 R-HSA-2161567 https://reactome.org/PathwayBrowser/#/R-HSA-2161567 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 IEA Homo sapiens 57783 R-HSA-2161614 https://reactome.org/PathwayBrowser/#/R-HSA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 TAS Homo sapiens 57783 R-HSA-2161651 https://reactome.org/PathwayBrowser/#/R-HSA-2161651 PGE2 is converted to PGF2a by CBR1 TAS Homo sapiens 57783 R-HSA-2161692 https://reactome.org/PathwayBrowser/#/R-HSA-2161692 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1 IEA Homo sapiens 57783 R-HSA-2161745 https://reactome.org/PathwayBrowser/#/R-HSA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 TAS Homo sapiens 57783 R-HSA-2161776 https://reactome.org/PathwayBrowser/#/R-HSA-2161776 5S-HETE is oxidised to 5-oxoETE by 5-HEDH TAS Homo sapiens 57783 R-HSA-2161789 https://reactome.org/PathwayBrowser/#/R-HSA-2161789 15S-HETE is oxidised to 15-oxoETE by 15-HEDH TAS Homo sapiens 57783 R-HSA-2161792 https://reactome.org/PathwayBrowser/#/R-HSA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 TAS Homo sapiens 57783 R-HSA-2161844 https://reactome.org/PathwayBrowser/#/R-HSA-2161844 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 IEA Homo sapiens 57783 R-HSA-2161890 https://reactome.org/PathwayBrowser/#/R-HSA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) TAS Homo sapiens 57783 R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) TAS Homo sapiens 57783 R-HSA-2161951 https://reactome.org/PathwayBrowser/#/R-HSA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 TAS Homo sapiens 57783 R-HSA-2161979 https://reactome.org/PathwayBrowser/#/R-HSA-2161979 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH TAS Homo sapiens 57783 R-HSA-2162191 https://reactome.org/PathwayBrowser/#/R-HSA-2162191 Unknown enzyme hydroxylates DMPhOH IEA Homo sapiens 57783 R-HSA-2395517 https://reactome.org/PathwayBrowser/#/R-HSA-2395517 NADPH transfers electrons to FDXR TAS Homo sapiens 57783 R-HSA-2408542 https://reactome.org/PathwayBrowser/#/R-HSA-2408542 GSSeSG is reduced to GSSeH and GSH by GSR IEA Homo sapiens 57783 R-HSA-2408548 https://reactome.org/PathwayBrowser/#/R-HSA-2408548 PAPSe is reduced to SeO3(2-) by PAPSe reductase IEA Homo sapiens 57783 R-HSA-2408558 https://reactome.org/PathwayBrowser/#/R-HSA-2408558 SeO3(2-) is reduced to H2Se by TXNRD1 IEA Homo sapiens 57783 R-HSA-2464803 https://reactome.org/PathwayBrowser/#/R-HSA-2464803 RDH8 reduces atRAL to atROL IEA Homo sapiens 57783 R-HSA-2464822 https://reactome.org/PathwayBrowser/#/R-HSA-2464822 RDH12 reduces atRAL to atROL TAS Homo sapiens 57783 R-HSA-2465921 https://reactome.org/PathwayBrowser/#/R-HSA-2465921 11cRDH oxidises 11cROL to 11cRAL TAS Homo sapiens 57783 R-HSA-2465940 https://reactome.org/PathwayBrowser/#/R-HSA-2465940 atRAL is reduced to atROL TAS Homo sapiens 57783 R-HSA-2466861 https://reactome.org/PathwayBrowser/#/R-HSA-2466861 Defective RDH12 does not reduce atRAL to atROL and causes LCA13 TAS Homo sapiens 57783 R-HSA-2471670 https://reactome.org/PathwayBrowser/#/R-HSA-2471670 Defective RDH12 does not reduce atRAL to atROL TAS Homo sapiens 57783 R-HSA-2564824 https://reactome.org/PathwayBrowser/#/R-HSA-2564824 NADPH reduces NDOR1:CIAPIN1 IEA Homo sapiens 57783 R-HSA-2855252 https://reactome.org/PathwayBrowser/#/R-HSA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL TAS Homo sapiens 57783 R-HSA-3149518 https://reactome.org/PathwayBrowser/#/R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl TAS Homo sapiens 57783 R-HSA-3149519 https://reactome.org/PathwayBrowser/#/R-HSA-3149519 MMACHC decyanates CNCbl TAS Homo sapiens 57783 R-HSA-3318563 https://reactome.org/PathwayBrowser/#/R-HSA-3318563 Defective MTRR does not convert cob(II)alamin to MeCbl TAS Homo sapiens 57783 R-HSA-3318576 https://reactome.org/PathwayBrowser/#/R-HSA-3318576 Defective MMACHC does not reduce Cbl TAS Homo sapiens 57783 R-HSA-3318590 https://reactome.org/PathwayBrowser/#/R-HSA-3318590 Defective MMACHC does not decyanate CNCbl TAS Homo sapiens 57783 R-HSA-3323050 https://reactome.org/PathwayBrowser/#/R-HSA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH TAS Homo sapiens 57783 R-HSA-3323079 https://reactome.org/PathwayBrowser/#/R-HSA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 57783 R-HSA-350869 https://reactome.org/PathwayBrowser/#/R-HSA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) TAS Homo sapiens 57783 R-HSA-389540 https://reactome.org/PathwayBrowser/#/R-HSA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 57783 R-HSA-390425 https://reactome.org/PathwayBrowser/#/R-HSA-390425 FAR1 reduces PalmCoA to HXOL TAS Homo sapiens 57783 R-HSA-390438 https://reactome.org/PathwayBrowser/#/R-HSA-390438 FAR2 reduces PalmCoA to HXOL TAS Homo sapiens 57783 R-HSA-418436 https://reactome.org/PathwayBrowser/#/R-HSA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) TAS Homo sapiens 57783 R-HSA-428123 https://reactome.org/PathwayBrowser/#/R-HSA-428123 KDSR reduces 3-ketosphingoid TAS Homo sapiens 57783 R-HSA-4419979 https://reactome.org/PathwayBrowser/#/R-HSA-4419979 SRD5A3 reduces pPNOL to DCHOL TAS Homo sapiens 57783 R-HSA-450971 https://reactome.org/PathwayBrowser/#/R-HSA-450971 NNT dimer transfers proton from NADPH to NAD+ TAS Homo sapiens 57783 R-HSA-450984 https://reactome.org/PathwayBrowser/#/R-HSA-450984 IDH2 dimer decarboxylates isocitrate TAS Homo sapiens 57783 R-HSA-469659 https://reactome.org/PathwayBrowser/#/R-HSA-469659 SRD5A1 dehydrogenates TEST to DHTEST TAS Homo sapiens 57783 R-HSA-4755572 https://reactome.org/PathwayBrowser/#/R-HSA-4755572 Defective SRD5A3 does not reduce pPNOL to DCHOL TAS Homo sapiens 57783 R-HSA-508040 https://reactome.org/PathwayBrowser/#/R-HSA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] TAS Homo sapiens 57783 R-HSA-514604 https://reactome.org/PathwayBrowser/#/R-HSA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) TAS Homo sapiens 57783 R-HSA-5218841 https://reactome.org/PathwayBrowser/#/R-HSA-5218841 NADPH oxidase 2 generates superoxide from oxygen TAS Homo sapiens 57783 R-HSA-5263614 https://reactome.org/PathwayBrowser/#/R-HSA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 TAS Homo sapiens 57783 R-HSA-5263616 https://reactome.org/PathwayBrowser/#/R-HSA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 TAS Homo sapiens 57783 R-HSA-5340226 https://reactome.org/PathwayBrowser/#/R-HSA-5340226 CYGB dioxygenates NO TAS Homo sapiens 57783 R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 57783 R-HSA-5419165 https://reactome.org/PathwayBrowser/#/R-HSA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL TAS Homo sapiens 57783 R-HSA-5423637 https://reactome.org/PathwayBrowser/#/R-HSA-5423637 AKR dimers reduce AFBDHO to AFBDOH TAS Homo sapiens 57783 R-HSA-5423647 https://reactome.org/PathwayBrowser/#/R-HSA-5423647 CYP2A13 oxidises AFM1 to AFM1E TAS Homo sapiens 57783 R-HSA-5423664 https://reactome.org/PathwayBrowser/#/R-HSA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 TAS Homo sapiens 57783 R-HSA-5423672 https://reactome.org/PathwayBrowser/#/R-HSA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO TAS Homo sapiens 57783 R-HSA-5423678 https://reactome.org/PathwayBrowser/#/R-HSA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 TAS Homo sapiens 57783 R-HSA-548818 https://reactome.org/PathwayBrowser/#/R-HSA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA TAS Homo sapiens 57783 R-HSA-548831 https://reactome.org/PathwayBrowser/#/R-HSA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA TAS Homo sapiens 57783 R-HSA-5580269 https://reactome.org/PathwayBrowser/#/R-HSA-5580269 Defective CYP11A1 does not cleave 20a,22b-DHCHOL TAS Homo sapiens 57783 R-HSA-5580292 https://reactome.org/PathwayBrowser/#/R-HSA-5580292 Defective CYP11B1 does not oxidise 11DCORT TAS Homo sapiens 57783 R-HSA-5600598 https://reactome.org/PathwayBrowser/#/R-HSA-5600598 Defective CYP11B2 does not oxidise 11DCORST TAS Homo sapiens 57783 R-HSA-5601843 https://reactome.org/PathwayBrowser/#/R-HSA-5601843 Defective CYP17A1 does not 17-hydroxylate PREG TAS Homo sapiens 57783 R-HSA-5601849 https://reactome.org/PathwayBrowser/#/R-HSA-5601849 Defective CYP19A1 does not convert ANDST to E1 TAS Homo sapiens 57783 R-HSA-5601976 https://reactome.org/PathwayBrowser/#/R-HSA-5601976 Defective CYP21A2 does not 21-hydroxylate PROG TAS Homo sapiens 57783 R-HSA-5602004 https://reactome.org/PathwayBrowser/#/R-HSA-5602004 Defective CYP24A1 does not 24-hydroxylate CALTOL TAS Homo sapiens 57783 R-HSA-5602050 https://reactome.org/PathwayBrowser/#/R-HSA-5602050 Defective CYP26C1 does not 4-hydroxylate 9cRA TAS Homo sapiens 57783 R-HSA-5602147 https://reactome.org/PathwayBrowser/#/R-HSA-5602147 Defective CYP2R1 does not 25-hydroxylate vitamin D TAS Homo sapiens 57783 R-HSA-5602170 https://reactome.org/PathwayBrowser/#/R-HSA-5602170 CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol TAS Homo sapiens 57783 R-HSA-5602186 https://reactome.org/PathwayBrowser/#/R-HSA-5602186 Defective CYP27B1 does not hydroxylate CDL TAS Homo sapiens 57783 R-HSA-5602272 https://reactome.org/PathwayBrowser/#/R-HSA-5602272 Defective CYP4F22 does not 20-hydroxylate TrXA3 TAS Homo sapiens 57783 R-HSA-5602295 https://reactome.org/PathwayBrowser/#/R-HSA-5602295 CYP4F22 20-hydroxylates TrXA3 TAS Homo sapiens 57783 R-HSA-5602885 https://reactome.org/PathwayBrowser/#/R-HSA-5602885 Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL TAS Homo sapiens 57783 R-HSA-5605147 https://reactome.org/PathwayBrowser/#/R-HSA-5605147 Defective CYP1B1 does not 4-hydroxylate EST17b TAS Homo sapiens 57783 R-HSA-5615668 https://reactome.org/PathwayBrowser/#/R-HSA-5615668 AKR1C3 reduces atRAL to atROL TAS Homo sapiens 57783 R-HSA-5652172 https://reactome.org/PathwayBrowser/#/R-HSA-5652172 AKR1B1 reduces Glc to D-sorbitol TAS Homo sapiens 57783 R-HSA-5661240 https://reactome.org/PathwayBrowser/#/R-HSA-5661240 DCXR tetramer reduces L-xylulose to xylitol TAS Homo sapiens 57783 R-HSA-5661256 https://reactome.org/PathwayBrowser/#/R-HSA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate TAS Homo sapiens 57783 R-HSA-5662851 https://reactome.org/PathwayBrowser/#/R-HSA-5662851 Defective DCXR does not reduce L-xylulose to xylitol TAS Homo sapiens 57783 R-HSA-5668629 https://reactome.org/PathwayBrowser/#/R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP TAS Homo sapiens 57783 R-HSA-5668718 https://reactome.org/PathwayBrowser/#/R-HSA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 57783 R-HSA-5668731 https://reactome.org/PathwayBrowser/#/R-HSA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 57783 R-HSA-5692232 https://reactome.org/PathwayBrowser/#/R-HSA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione TAS Homo sapiens 57783 R-HSA-5692283 https://reactome.org/PathwayBrowser/#/R-HSA-5692283 ALD3A1 oxidises 4HPCP to CXPA TAS Homo sapiens 57783 R-HSA-5693390 https://reactome.org/PathwayBrowser/#/R-HSA-5693390 HSD17B11 dehydrogenates EST17b to E1 TAS Homo sapiens 57783 R-HSA-5696822 https://reactome.org/PathwayBrowser/#/R-HSA-5696822 AKR1B15 reduces EST17b to E1 TAS Homo sapiens 57783 R-HSA-6782296 https://reactome.org/PathwayBrowser/#/R-HSA-6782296 DUS2:EPRS reduces uridine to dihydrouridine in tRNAs IEA Homo sapiens 57783 R-HSA-6783955 https://reactome.org/PathwayBrowser/#/R-HSA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 57783 R-HSA-6785244 https://reactome.org/PathwayBrowser/#/R-HSA-6785244 Defective CYP11B2 does not oxidise 18HCORST TAS Homo sapiens 57783 R-HSA-6785245 https://reactome.org/PathwayBrowser/#/R-HSA-6785245 Defective CYP11B2 does not oxidise CORST TAS Homo sapiens 57783 R-HSA-6786239 https://reactome.org/PathwayBrowser/#/R-HSA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE TAS Homo sapiens 57783 R-HSA-6787642 https://reactome.org/PathwayBrowser/#/R-HSA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc TAS Homo sapiens 57783 R-HSA-6789092 https://reactome.org/PathwayBrowser/#/R-HSA-6789092 NOX2 generates superoxide anion from oxygen TAS Homo sapiens 57783 R-HSA-6799722 https://reactome.org/PathwayBrowser/#/R-HSA-6799722 TP53I3 oxidoreductase generates unstable semiquinones TAS Homo sapiens 57783 R-HSA-6806967 https://reactome.org/PathwayBrowser/#/R-HSA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH TAS Homo sapiens 57783 R-HSA-6807053 https://reactome.org/PathwayBrowser/#/R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL TAS Homo sapiens 57783 R-HSA-6807055 https://reactome.org/PathwayBrowser/#/R-HSA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL TAS Homo sapiens 57783 R-HSA-6807064 https://reactome.org/PathwayBrowser/#/R-HSA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL TAS Homo sapiens 57783 R-HSA-6807557 https://reactome.org/PathwayBrowser/#/R-HSA-6807557 NOX4, NOX5 reduce O2 to O2.- TAS Homo sapiens 57783 R-HSA-6808487 https://reactome.org/PathwayBrowser/#/R-HSA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 57783 R-HSA-6808496 https://reactome.org/PathwayBrowser/#/R-HSA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 57783 R-HSA-6810594 https://reactome.org/PathwayBrowser/#/R-HSA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 57783 R-HSA-70377 https://reactome.org/PathwayBrowser/#/R-HSA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ TAS Homo sapiens 57783 R-HSA-70577 https://reactome.org/PathwayBrowser/#/R-HSA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA TAS Homo sapiens 57783 R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] TAS Homo sapiens 57783 R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] TAS Homo sapiens 57783 R-HSA-70938 https://reactome.org/PathwayBrowser/#/R-HSA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O TAS Homo sapiens 57783 R-HSA-71200 https://reactome.org/PathwayBrowser/#/R-HSA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O TAS Homo sapiens 57783 R-HSA-71299 https://reactome.org/PathwayBrowser/#/R-HSA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ TAS Homo sapiens 57783 R-HSA-71682 https://reactome.org/PathwayBrowser/#/R-HSA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 57783 R-HSA-73585 https://reactome.org/PathwayBrowser/#/R-HSA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ TAS Homo sapiens 57783 R-HSA-73616 https://reactome.org/PathwayBrowser/#/R-HSA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ TAS Homo sapiens 57783 R-HSA-73646 https://reactome.org/PathwayBrowser/#/R-HSA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ TAS Homo sapiens 57783 R-HSA-74872 https://reactome.org/PathwayBrowser/#/R-HSA-74872 RDH10,11 oxidise 11cROL to 11cRAL TAS Homo sapiens 57783 R-HSA-75872 https://reactome.org/PathwayBrowser/#/R-HSA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O TAS Homo sapiens 57783 R-HSA-75883 https://reactome.org/PathwayBrowser/#/R-HSA-75883 DHRS7B reduces GO3P to HXDG3P TAS Homo sapiens 57783 R-HSA-76494 https://reactome.org/PathwayBrowser/#/R-HSA-76494 POR reduces CYP450:Fe3+ to CYP450:Fe2+ TAS Homo sapiens 57783 R-HSA-804969 https://reactome.org/PathwayBrowser/#/R-HSA-804969 HSD17B1 hydrogenates E1 to EST17b TAS Homo sapiens 57783 R-HSA-880053 https://reactome.org/PathwayBrowser/#/R-HSA-880053 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] TAS Homo sapiens 57783 R-HSA-8862137 https://reactome.org/PathwayBrowser/#/R-HSA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 57783 R-HSA-8862152 https://reactome.org/PathwayBrowser/#/R-HSA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP TAS Homo sapiens 57783 R-HSA-8865107 https://reactome.org/PathwayBrowser/#/R-HSA-8865107 MICAL1 produces NADP+, H2O2 TAS Homo sapiens 57783 R-HSA-8937419 https://reactome.org/PathwayBrowser/#/R-HSA-8937419 CBR3 reduces DOX to DOXOL TAS Homo sapiens 57783 R-HSA-8952873 https://reactome.org/PathwayBrowser/#/R-HSA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA TAS Homo sapiens 57783 R-HSA-9012036 https://reactome.org/PathwayBrowser/#/R-HSA-9012036 ME1 tetramer decarboxylates MAL to PYR TAS Homo sapiens 57783 R-HSA-9012349 https://reactome.org/PathwayBrowser/#/R-HSA-9012349 ME3 tetramer decarboxylates MAL to PYR TAS Homo sapiens 57783 R-HSA-9018867 https://reactome.org/PathwayBrowser/#/R-HSA-9018867 5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2 TAS Homo sapiens 57783 R-HSA-9018874 https://reactome.org/PathwayBrowser/#/R-HSA-9018874 CYP monooxygenates EPA to 18(S)-HpEPE TAS Homo sapiens 57783 R-HSA-9018901 https://reactome.org/PathwayBrowser/#/R-HSA-9018901 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HpEPE to 18(R)-RvE2 TAS Homo sapiens 57783 R-HSA-9020255 https://reactome.org/PathwayBrowser/#/R-HSA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA TAS Homo sapiens 57783 R-HSA-9020256 https://reactome.org/PathwayBrowser/#/R-HSA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA TAS Homo sapiens 57783 R-HSA-9020262 https://reactome.org/PathwayBrowser/#/R-HSA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA TAS Homo sapiens 57783 R-HSA-9020277 https://reactome.org/PathwayBrowser/#/R-HSA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA TAS Homo sapiens 57783 R-HSA-9020278 https://reactome.org/PathwayBrowser/#/R-HSA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA TAS Homo sapiens 57783 R-HSA-9024881 https://reactome.org/PathwayBrowser/#/R-HSA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA TAS Homo sapiens 57783 R-HSA-9024983 https://reactome.org/PathwayBrowser/#/R-HSA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA TAS Homo sapiens 57783 R-HSA-9025995 https://reactome.org/PathwayBrowser/#/R-HSA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 TAS Homo sapiens 57783 R-HSA-9025999 https://reactome.org/PathwayBrowser/#/R-HSA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 TAS Homo sapiens 57783 R-HSA-9026007 https://reactome.org/PathwayBrowser/#/R-HSA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 TAS Homo sapiens 57783 R-HSA-9026917 https://reactome.org/PathwayBrowser/#/R-HSA-9026917 Lipoxygenase dehydrogenates 7(S),17(S)-diHp-DHA to 7S(8)-epoxy-17(S)-HDHA TAS Homo sapiens 57783 R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 57783 R-HSA-9027043 https://reactome.org/PathwayBrowser/#/R-HSA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA TAS Homo sapiens 57783 R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 57783 R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 57783 R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 57783 R-HSA-9027531 https://reactome.org/PathwayBrowser/#/R-HSA-9027531 Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA TAS Homo sapiens 57783 R-HSA-9027562 https://reactome.org/PathwayBrowser/#/R-HSA-9027562 Dehydrogenase dehydrogenates 17-HDHA to 17-oxo-DHA TAS Homo sapiens 57783 R-HSA-9027598 https://reactome.org/PathwayBrowser/#/R-HSA-9027598 Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3 TAS Homo sapiens 57783 R-HSA-9027600 https://reactome.org/PathwayBrowser/#/R-HSA-9027600 Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3 TAS Homo sapiens 57783 R-HSA-9027625 https://reactome.org/PathwayBrowser/#/R-HSA-9027625 5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3 TAS Homo sapiens 57783 R-HSA-9027631 https://reactome.org/PathwayBrowser/#/R-HSA-9027631 5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA TAS Homo sapiens 57783 R-HSA-9027632 https://reactome.org/PathwayBrowser/#/R-HSA-9027632 5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA TAS Homo sapiens 57783 R-HSA-9035954 https://reactome.org/PathwayBrowser/#/R-HSA-9035954 Defective CYP17A1 does not 17-hydroxylate P4 TAS Homo sapiens 57783 R-HSA-9035956 https://reactome.org/PathwayBrowser/#/R-HSA-9035956 Defective CYP17A1 does not cleave 17aHPROG TAS Homo sapiens 57783 R-HSA-9035960 https://reactome.org/PathwayBrowser/#/R-HSA-9035960 Defective CYP27A1 does not 27-hydroxylate 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 57783 R-HSA-9037761 https://reactome.org/PathwayBrowser/#/R-HSA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 TAS Homo sapiens 57783 R-HSA-917811 https://reactome.org/PathwayBrowser/#/R-HSA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ TAS Homo sapiens 57783 R-HSA-9673797 https://reactome.org/PathwayBrowser/#/R-HSA-9673797 NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 57783 R-HSA-9698758 https://reactome.org/PathwayBrowser/#/R-HSA-9698758 FLT3 ITD- and NOX4-dependent H2O2 production TAS Homo sapiens 57783 R-HSA-9705713 https://reactome.org/PathwayBrowser/#/R-HSA-9705713 SRD5A2 dehydrogenates TEST to DHTEST TAS Homo sapiens 57783 R-HSA-9705714 https://reactome.org/PathwayBrowser/#/R-HSA-9705714 SRD5A3 dehydrogenates TEST to DHTEST TAS Homo sapiens 57783 R-HSA-9709098 https://reactome.org/PathwayBrowser/#/R-HSA-9709098 DHFR dimer reduces FOLA to DHF TAS Homo sapiens 57783 R-HSA-9753285 https://reactome.org/PathwayBrowser/#/R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI TAS Homo sapiens 57783 R-HSA-9755937 https://reactome.org/PathwayBrowser/#/R-HSA-9755937 DHCR24 reduces LAN to 24,25-dhLAN TAS Homo sapiens 57783 R-HSA-9756138 https://reactome.org/PathwayBrowser/#/R-HSA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL TAS Homo sapiens 57783 R-HSA-9756162 https://reactome.org/PathwayBrowser/#/R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV TAS Homo sapiens 57783 R-HSA-9756169 https://reactome.org/PathwayBrowser/#/R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV TAS Homo sapiens 57783 R-HSA-9756180 https://reactome.org/PathwayBrowser/#/R-HSA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL TAS Homo sapiens 57783 R-HSA-975629 https://reactome.org/PathwayBrowser/#/R-HSA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL TAS Homo sapiens 57783 R-HSA-9757706 https://reactome.org/PathwayBrowser/#/R-HSA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell TAS Homo sapiens 57783 R-HSA-9758682 https://reactome.org/PathwayBrowser/#/R-HSA-9758682 AKR1C1 hydrogenates PREDN,PREDL TAS Homo sapiens 57783 R-HSA-9759259 https://reactome.org/PathwayBrowser/#/R-HSA-9759259 HSD11B2 dehydrogenates PREDL to PREDN TAS Homo sapiens 57783 R-MMU-1222376 https://reactome.org/PathwayBrowser/#/R-MMU-1222376 NOX2 generates superoxide from oxygen IEA Mus musculus 57783 R-MMU-1475414 https://reactome.org/PathwayBrowser/#/R-MMU-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Mus musculus 57783 R-MMU-1497770 https://reactome.org/PathwayBrowser/#/R-MMU-1497770 Salvage - BH2 is reduced to BH4 by Dhfr TAS Mus musculus 57783 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 57783 R-MMU-1497869 https://reactome.org/PathwayBrowser/#/R-MMU-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Mus musculus 57783 R-MMU-156526 https://reactome.org/PathwayBrowser/#/R-MMU-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Mus musculus 57783 R-MMU-1655453 https://reactome.org/PathwayBrowser/#/R-MMU-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Mus musculus 57783 R-MMU-189384 https://reactome.org/PathwayBrowser/#/R-MMU-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Mus musculus 57783 R-MMU-189398 https://reactome.org/PathwayBrowser/#/R-MMU-189398 HMOX1 dimer, HMOX2 cleave heme IEA Mus musculus 57783 R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 57783 R-MMU-191352 https://reactome.org/PathwayBrowser/#/R-MMU-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Mus musculus 57783 R-MMU-191402 https://reactome.org/PathwayBrowser/#/R-MMU-191402 Reduction of presqualene diphosphate to form squalene IEA Mus musculus 57783 R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 57783 R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 57783 R-MMU-191999 https://reactome.org/PathwayBrowser/#/R-MMU-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Mus musculus 57783 R-MMU-192033 https://reactome.org/PathwayBrowser/#/R-MMU-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Mus musculus 57783 R-MMU-192036 https://reactome.org/PathwayBrowser/#/R-MMU-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Mus musculus 57783 R-MMU-192042 https://reactome.org/PathwayBrowser/#/R-MMU-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 57783 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 57783 R-MMU-192054 https://reactome.org/PathwayBrowser/#/R-MMU-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Mus musculus 57783 R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 57783 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 57783 R-MMU-192067 https://reactome.org/PathwayBrowser/#/R-MMU-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Mus musculus 57783 R-MMU-192123 https://reactome.org/PathwayBrowser/#/R-MMU-192123 CYP27A1 27-hydroxylates CHOL IEA Mus musculus 57783 R-MMU-192157 https://reactome.org/PathwayBrowser/#/R-MMU-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Mus musculus 57783 R-MMU-192160 https://reactome.org/PathwayBrowser/#/R-MMU-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Mus musculus 57783 R-MMU-192178 https://reactome.org/PathwayBrowser/#/R-MMU-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Mus musculus 57783 R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 57783 R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 57783 R-MMU-193064 https://reactome.org/PathwayBrowser/#/R-MMU-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Mus musculus 57783 R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 57783 R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 57783 R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 57783 R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 57783 R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 57783 R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 57783 R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 57783 R-MMU-193393 https://reactome.org/PathwayBrowser/#/R-MMU-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Mus musculus 57783 R-MMU-193460 https://reactome.org/PathwayBrowser/#/R-MMU-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Mus musculus 57783 R-MMU-193497 https://reactome.org/PathwayBrowser/#/R-MMU-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Mus musculus 57783 R-MMU-193709 https://reactome.org/PathwayBrowser/#/R-MMU-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Mus musculus 57783 R-MMU-193713 https://reactome.org/PathwayBrowser/#/R-MMU-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Mus musculus 57783 R-MMU-193719 https://reactome.org/PathwayBrowser/#/R-MMU-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 57783 R-MMU-193737 https://reactome.org/PathwayBrowser/#/R-MMU-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Mus musculus 57783 R-MMU-193746 https://reactome.org/PathwayBrowser/#/R-MMU-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Mus musculus 57783 R-MMU-193755 https://reactome.org/PathwayBrowser/#/R-MMU-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Mus musculus 57783 R-MMU-193758 https://reactome.org/PathwayBrowser/#/R-MMU-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Mus musculus 57783 R-MMU-193780 https://reactome.org/PathwayBrowser/#/R-MMU-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Mus musculus 57783 R-MMU-193781 https://reactome.org/PathwayBrowser/#/R-MMU-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Mus musculus 57783 R-MMU-193787 https://reactome.org/PathwayBrowser/#/R-MMU-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Mus musculus 57783 R-MMU-193792 https://reactome.org/PathwayBrowser/#/R-MMU-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Mus musculus 57783 R-MMU-193800 https://reactome.org/PathwayBrowser/#/R-MMU-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Mus musculus 57783 R-MMU-193821 https://reactome.org/PathwayBrowser/#/R-MMU-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Mus musculus 57783 R-MMU-193824 https://reactome.org/PathwayBrowser/#/R-MMU-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Mus musculus 57783 R-MMU-193841 https://reactome.org/PathwayBrowser/#/R-MMU-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Mus musculus 57783 R-MMU-193845 https://reactome.org/PathwayBrowser/#/R-MMU-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Mus musculus 57783 R-MMU-193964 https://reactome.org/PathwayBrowser/#/R-MMU-193964 CYP21A2 21-hydroxylates PROG IEA Mus musculus 57783 R-MMU-193965 https://reactome.org/PathwayBrowser/#/R-MMU-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Mus musculus 57783 R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 57783 R-MMU-193995 https://reactome.org/PathwayBrowser/#/R-MMU-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Mus musculus 57783 R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 57783 R-MMU-194017 https://reactome.org/PathwayBrowser/#/R-MMU-194017 CYP11B2 oxidises 11DCORST to CORST IEA Mus musculus 57783 R-MMU-194023 https://reactome.org/PathwayBrowser/#/R-MMU-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Mus musculus 57783 R-MMU-194632 https://reactome.org/PathwayBrowser/#/R-MMU-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Mus musculus 57783 R-MMU-194641 https://reactome.org/PathwayBrowser/#/R-MMU-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 57783 R-MMU-194669 https://reactome.org/PathwayBrowser/#/R-MMU-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 57783 R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 57783 R-MMU-194689 https://reactome.org/PathwayBrowser/#/R-MMU-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Mus musculus 57783 R-MMU-194698 https://reactome.org/PathwayBrowser/#/R-MMU-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Mus musculus 57783 R-MMU-195664 https://reactome.org/PathwayBrowser/#/R-MMU-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Mus musculus 57783 R-MMU-196060 https://reactome.org/PathwayBrowser/#/R-MMU-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Mus musculus 57783 R-MMU-196402 https://reactome.org/PathwayBrowser/#/R-MMU-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Mus musculus 57783 R-MMU-196417 https://reactome.org/PathwayBrowser/#/R-MMU-196417 Reduction of desmosterol to cholesterol IEA Mus musculus 57783 R-MMU-197963 https://reactome.org/PathwayBrowser/#/R-MMU-197963 DHFR2 reduces FOLA to DHF IEA Mus musculus 57783 R-MMU-197972 https://reactome.org/PathwayBrowser/#/R-MMU-197972 DHF is reduced to tetrahydrofolate (THF) IEA Mus musculus 57783 R-MMU-200644 https://reactome.org/PathwayBrowser/#/R-MMU-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Mus musculus 57783 R-MMU-200676 https://reactome.org/PathwayBrowser/#/R-MMU-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Mus musculus 57783 R-MMU-200718 https://reactome.org/PathwayBrowser/#/R-MMU-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Mus musculus 57783 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 57783 R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 57783 R-MMU-209772 https://reactome.org/PathwayBrowser/#/R-MMU-209772 Thyroxine is deiodinated to triiodothyronine IEA Mus musculus 57783 R-MMU-209845 https://reactome.org/PathwayBrowser/#/R-MMU-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Mus musculus 57783 R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 57783 R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus 57783 R-MMU-211923 https://reactome.org/PathwayBrowser/#/R-MMU-211923 CYP26C1 4-hydroxylates 9cRA IEA Mus musculus 57783 R-MMU-211950 https://reactome.org/PathwayBrowser/#/R-MMU-211950 CYP24A1 24-hydroxylates CTL IEA Mus musculus 57783 R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 57783 R-MMU-2161549 https://reactome.org/PathwayBrowser/#/R-MMU-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Mus musculus 57783 R-MMU-2161614 https://reactome.org/PathwayBrowser/#/R-MMU-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Mus musculus 57783 R-MMU-2161638 https://reactome.org/PathwayBrowser/#/R-MMU-2161638 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by Ptgr2 TAS Mus musculus 57783 R-MMU-2161651 https://reactome.org/PathwayBrowser/#/R-MMU-2161651 PGE2 is converted to PGF2a by CBR1 IEA Mus musculus 57783 R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus 57783 R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus 57783 R-MMU-2161890 https://reactome.org/PathwayBrowser/#/R-MMU-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Mus musculus 57783 R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Mus musculus 57783 R-MMU-2161951 https://reactome.org/PathwayBrowser/#/R-MMU-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Mus musculus 57783 R-MMU-2395517 https://reactome.org/PathwayBrowser/#/R-MMU-2395517 NADPH transfers electrons to FDXR IEA Mus musculus 57783 R-MMU-2464822 https://reactome.org/PathwayBrowser/#/R-MMU-2464822 RDH12 reduces atRAL to atROL IEA Mus musculus 57783 R-MMU-2465940 https://reactome.org/PathwayBrowser/#/R-MMU-2465940 atRAL is reduced to atROL IEA Mus musculus 57783 R-MMU-2855252 https://reactome.org/PathwayBrowser/#/R-MMU-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Mus musculus 57783 R-MMU-3149518 https://reactome.org/PathwayBrowser/#/R-MMU-3149518 MTRR reduces cob(II)alamin to meCbl IEA Mus musculus 57783 R-MMU-3149519 https://reactome.org/PathwayBrowser/#/R-MMU-3149519 MMACHC decyanates CNCbl IEA Mus musculus 57783 R-MMU-3323050 https://reactome.org/PathwayBrowser/#/R-MMU-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Mus musculus 57783 R-MMU-3323079 https://reactome.org/PathwayBrowser/#/R-MMU-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 57783 R-MMU-350869 https://reactome.org/PathwayBrowser/#/R-MMU-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Mus musculus 57783 R-MMU-389540 https://reactome.org/PathwayBrowser/#/R-MMU-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 57783 R-MMU-390425 https://reactome.org/PathwayBrowser/#/R-MMU-390425 FAR1 reduces PalmCoA to HXOL IEA Mus musculus 57783 R-MMU-390438 https://reactome.org/PathwayBrowser/#/R-MMU-390438 FAR2 reduces PalmCoA to HXOL IEA Mus musculus 57783 R-MMU-418436 https://reactome.org/PathwayBrowser/#/R-MMU-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Mus musculus 57783 R-MMU-428123 https://reactome.org/PathwayBrowser/#/R-MMU-428123 KDSR reduces 3-ketosphingoid IEA Mus musculus 57783 R-MMU-4419979 https://reactome.org/PathwayBrowser/#/R-MMU-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Mus musculus 57783 R-MMU-450971 https://reactome.org/PathwayBrowser/#/R-MMU-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Mus musculus 57783 R-MMU-450984 https://reactome.org/PathwayBrowser/#/R-MMU-450984 IDH2 dimer decarboxylates isocitrate IEA Mus musculus 57783 R-MMU-469659 https://reactome.org/PathwayBrowser/#/R-MMU-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Mus musculus 57783 R-MMU-508040 https://reactome.org/PathwayBrowser/#/R-MMU-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Mus musculus 57783 R-MMU-514604 https://reactome.org/PathwayBrowser/#/R-MMU-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Mus musculus 57783 R-MMU-5218841 https://reactome.org/PathwayBrowser/#/R-MMU-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Mus musculus 57783 R-MMU-5263614 https://reactome.org/PathwayBrowser/#/R-MMU-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Mus musculus 57783 R-MMU-5263616 https://reactome.org/PathwayBrowser/#/R-MMU-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Mus musculus 57783 R-MMU-5340226 https://reactome.org/PathwayBrowser/#/R-MMU-5340226 CYGB dioxygenates NO IEA Mus musculus 57783 R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 57783 R-MMU-5419165 https://reactome.org/PathwayBrowser/#/R-MMU-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Mus musculus 57783 R-MMU-5423637 https://reactome.org/PathwayBrowser/#/R-MMU-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Mus musculus 57783 R-MMU-5423647 https://reactome.org/PathwayBrowser/#/R-MMU-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Mus musculus 57783 R-MMU-5423664 https://reactome.org/PathwayBrowser/#/R-MMU-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Mus musculus 57783 R-MMU-5423672 https://reactome.org/PathwayBrowser/#/R-MMU-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Mus musculus 57783 R-MMU-5423678 https://reactome.org/PathwayBrowser/#/R-MMU-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Mus musculus 57783 R-MMU-548818 https://reactome.org/PathwayBrowser/#/R-MMU-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Mus musculus 57783 R-MMU-548831 https://reactome.org/PathwayBrowser/#/R-MMU-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Mus musculus 57783 R-MMU-5602295 https://reactome.org/PathwayBrowser/#/R-MMU-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Mus musculus 57783 R-MMU-5615668 https://reactome.org/PathwayBrowser/#/R-MMU-5615668 AKR1C3 reduces atRAL to atROL IEA Mus musculus 57783 R-MMU-5652172 https://reactome.org/PathwayBrowser/#/R-MMU-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Mus musculus 57783 R-MMU-5661240 https://reactome.org/PathwayBrowser/#/R-MMU-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Mus musculus 57783 R-MMU-5661256 https://reactome.org/PathwayBrowser/#/R-MMU-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Mus musculus 57783 R-MMU-5668629 https://reactome.org/PathwayBrowser/#/R-MMU-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Mus musculus 57783 R-MMU-5668718 https://reactome.org/PathwayBrowser/#/R-MMU-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 57783 R-MMU-5668731 https://reactome.org/PathwayBrowser/#/R-MMU-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 57783 R-MMU-5692232 https://reactome.org/PathwayBrowser/#/R-MMU-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Mus musculus 57783 R-MMU-5692283 https://reactome.org/PathwayBrowser/#/R-MMU-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Mus musculus 57783 R-MMU-5693390 https://reactome.org/PathwayBrowser/#/R-MMU-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Mus musculus 57783 R-MMU-5696822 https://reactome.org/PathwayBrowser/#/R-MMU-5696822 AKR1B15 reduces EST17b to E1 IEA Mus musculus 57783 R-MMU-6783955 https://reactome.org/PathwayBrowser/#/R-MMU-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 57783 R-MMU-6786239 https://reactome.org/PathwayBrowser/#/R-MMU-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Mus musculus 57783 R-MMU-6787642 https://reactome.org/PathwayBrowser/#/R-MMU-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Mus musculus 57783 R-MMU-6789092 https://reactome.org/PathwayBrowser/#/R-MMU-6789092 NOX2 generates superoxide anion from oxygen IEA Mus musculus 57783 R-MMU-6806967 https://reactome.org/PathwayBrowser/#/R-MMU-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Mus musculus 57783 R-MMU-6807053 https://reactome.org/PathwayBrowser/#/R-MMU-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Mus musculus 57783 R-MMU-6807055 https://reactome.org/PathwayBrowser/#/R-MMU-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Mus musculus 57783 R-MMU-6807064 https://reactome.org/PathwayBrowser/#/R-MMU-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Mus musculus 57783 R-MMU-6807557 https://reactome.org/PathwayBrowser/#/R-MMU-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Mus musculus 57783 R-MMU-6808487 https://reactome.org/PathwayBrowser/#/R-MMU-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 57783 R-MMU-6808496 https://reactome.org/PathwayBrowser/#/R-MMU-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 57783 R-MMU-6810594 https://reactome.org/PathwayBrowser/#/R-MMU-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 57783 R-MMU-70377 https://reactome.org/PathwayBrowser/#/R-MMU-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Mus musculus 57783 R-MMU-70577 https://reactome.org/PathwayBrowser/#/R-MMU-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Mus musculus 57783 R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Mus musculus 57783 R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Mus musculus 57783 R-MMU-70938 https://reactome.org/PathwayBrowser/#/R-MMU-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Mus musculus 57783 R-MMU-71200 https://reactome.org/PathwayBrowser/#/R-MMU-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Mus musculus 57783 R-MMU-71299 https://reactome.org/PathwayBrowser/#/R-MMU-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Mus musculus 57783 R-MMU-71682 https://reactome.org/PathwayBrowser/#/R-MMU-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 57783 R-MMU-73585 https://reactome.org/PathwayBrowser/#/R-MMU-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Mus musculus 57783 R-MMU-73616 https://reactome.org/PathwayBrowser/#/R-MMU-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Mus musculus 57783 R-MMU-73646 https://reactome.org/PathwayBrowser/#/R-MMU-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Mus musculus 57783 R-MMU-74872 https://reactome.org/PathwayBrowser/#/R-MMU-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Mus musculus 57783 R-MMU-75872 https://reactome.org/PathwayBrowser/#/R-MMU-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Mus musculus 57783 R-MMU-75883 https://reactome.org/PathwayBrowser/#/R-MMU-75883 DHRS7B reduces GO3P to HXDG3P IEA Mus musculus 57783 R-MMU-804969 https://reactome.org/PathwayBrowser/#/R-MMU-804969 HSD17B1 hydrogenates E1 to EST17b IEA Mus musculus 57783 R-MMU-8862137 https://reactome.org/PathwayBrowser/#/R-MMU-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 57783 R-MMU-8862152 https://reactome.org/PathwayBrowser/#/R-MMU-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Mus musculus 57783 R-MMU-8937419 https://reactome.org/PathwayBrowser/#/R-MMU-8937419 CBR3 reduces DOX to DOXOL IEA Mus musculus 57783 R-MMU-8952873 https://reactome.org/PathwayBrowser/#/R-MMU-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Mus musculus 57783 R-MMU-9012036 https://reactome.org/PathwayBrowser/#/R-MMU-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Mus musculus 57783 R-MMU-9012349 https://reactome.org/PathwayBrowser/#/R-MMU-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Mus musculus 57783 R-MMU-9020255 https://reactome.org/PathwayBrowser/#/R-MMU-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Mus musculus 57783 R-MMU-9020256 https://reactome.org/PathwayBrowser/#/R-MMU-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Mus musculus 57783 R-MMU-9020262 https://reactome.org/PathwayBrowser/#/R-MMU-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Mus musculus 57783 R-MMU-9020277 https://reactome.org/PathwayBrowser/#/R-MMU-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Mus musculus 57783 R-MMU-9020278 https://reactome.org/PathwayBrowser/#/R-MMU-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Mus musculus 57783 R-MMU-9024881 https://reactome.org/PathwayBrowser/#/R-MMU-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Mus musculus 57783 R-MMU-9024983 https://reactome.org/PathwayBrowser/#/R-MMU-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Mus musculus 57783 R-MMU-9025995 https://reactome.org/PathwayBrowser/#/R-MMU-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Mus musculus 57783 R-MMU-9025999 https://reactome.org/PathwayBrowser/#/R-MMU-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Mus musculus 57783 R-MMU-9026007 https://reactome.org/PathwayBrowser/#/R-MMU-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Mus musculus 57783 R-MMU-9027043 https://reactome.org/PathwayBrowser/#/R-MMU-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Mus musculus 57783 R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 57783 R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 57783 R-MMU-9037761 https://reactome.org/PathwayBrowser/#/R-MMU-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Mus musculus 57783 R-MMU-917811 https://reactome.org/PathwayBrowser/#/R-MMU-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Mus musculus 57783 R-MMU-9705713 https://reactome.org/PathwayBrowser/#/R-MMU-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Mus musculus 57783 R-MMU-9705714 https://reactome.org/PathwayBrowser/#/R-MMU-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Mus musculus 57783 R-MMU-9709098 https://reactome.org/PathwayBrowser/#/R-MMU-9709098 DHFR dimer reduces FOLA to DHF IEA Mus musculus 57783 R-MMU-9753285 https://reactome.org/PathwayBrowser/#/R-MMU-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Mus musculus 57783 R-MMU-9755937 https://reactome.org/PathwayBrowser/#/R-MMU-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Mus musculus 57783 R-MMU-9756138 https://reactome.org/PathwayBrowser/#/R-MMU-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Mus musculus 57783 R-MMU-9756162 https://reactome.org/PathwayBrowser/#/R-MMU-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Mus musculus 57783 R-MMU-9756169 https://reactome.org/PathwayBrowser/#/R-MMU-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Mus musculus 57783 R-MMU-9756180 https://reactome.org/PathwayBrowser/#/R-MMU-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Mus musculus 57783 R-MMU-975629 https://reactome.org/PathwayBrowser/#/R-MMU-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Mus musculus 57783 R-MMU-9757706 https://reactome.org/PathwayBrowser/#/R-MMU-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Mus musculus 57783 R-MMU-9758682 https://reactome.org/PathwayBrowser/#/R-MMU-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Mus musculus 57783 R-MMU-9759259 https://reactome.org/PathwayBrowser/#/R-MMU-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Mus musculus 57783 R-MTU-879322 https://reactome.org/PathwayBrowser/#/R-MTU-879322 mycothione is reduced to mycothiol TAS Mycobacterium tuberculosis 57783 R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 57783 R-MTU-964842 https://reactome.org/PathwayBrowser/#/R-MTU-964842 Shikimate results from hydration of DHS TAS Mycobacterium tuberculosis 57783 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 57783 R-PFA-193064 https://reactome.org/PathwayBrowser/#/R-PFA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Plasmodium falciparum 57783 R-PFA-200644 https://reactome.org/PathwayBrowser/#/R-PFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Plasmodium falciparum 57783 R-PFA-200718 https://reactome.org/PathwayBrowser/#/R-PFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Plasmodium falciparum 57783 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 57783 R-PFA-2395517 https://reactome.org/PathwayBrowser/#/R-PFA-2395517 NADPH transfers electrons to FDXR IEA Plasmodium falciparum 57783 R-PFA-3323079 https://reactome.org/PathwayBrowser/#/R-PFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 57783 R-PFA-418436 https://reactome.org/PathwayBrowser/#/R-PFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Plasmodium falciparum 57783 R-PFA-428123 https://reactome.org/PathwayBrowser/#/R-PFA-428123 KDSR reduces 3-ketosphingoid IEA Plasmodium falciparum 57783 R-PFA-4419979 https://reactome.org/PathwayBrowser/#/R-PFA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Plasmodium falciparum 57783 R-PFA-450971 https://reactome.org/PathwayBrowser/#/R-PFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Plasmodium falciparum 57783 R-PFA-450984 https://reactome.org/PathwayBrowser/#/R-PFA-450984 IDH2 dimer decarboxylates isocitrate IEA Plasmodium falciparum 57783 R-PFA-5263614 https://reactome.org/PathwayBrowser/#/R-PFA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Plasmodium falciparum 57783 R-PFA-5263616 https://reactome.org/PathwayBrowser/#/R-PFA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Plasmodium falciparum 57783 R-PFA-548818 https://reactome.org/PathwayBrowser/#/R-PFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Plasmodium falciparum 57783 R-PFA-548831 https://reactome.org/PathwayBrowser/#/R-PFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Plasmodium falciparum 57783 R-PFA-6783955 https://reactome.org/PathwayBrowser/#/R-PFA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 57783 R-PFA-6787642 https://reactome.org/PathwayBrowser/#/R-PFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Plasmodium falciparum 57783 R-PFA-6806967 https://reactome.org/PathwayBrowser/#/R-PFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Plasmodium falciparum 57783 R-PFA-70377 https://reactome.org/PathwayBrowser/#/R-PFA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Plasmodium falciparum 57783 R-PFA-71682 https://reactome.org/PathwayBrowser/#/R-PFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 57783 R-PFA-73646 https://reactome.org/PathwayBrowser/#/R-PFA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Plasmodium falciparum 57783 R-PFA-8862152 https://reactome.org/PathwayBrowser/#/R-PFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Plasmodium falciparum 57783 R-PFA-9705714 https://reactome.org/PathwayBrowser/#/R-PFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Plasmodium falciparum 57783 R-RNO-1222376 https://reactome.org/PathwayBrowser/#/R-RNO-1222376 NOX2 generates superoxide from oxygen IEA Rattus norvegicus 57783 R-RNO-1475414 https://reactome.org/PathwayBrowser/#/R-RNO-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Rattus norvegicus 57783 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 57783 R-RNO-1497869 https://reactome.org/PathwayBrowser/#/R-RNO-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Rattus norvegicus 57783 R-RNO-156526 https://reactome.org/PathwayBrowser/#/R-RNO-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Rattus norvegicus 57783 R-RNO-1655453 https://reactome.org/PathwayBrowser/#/R-RNO-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Rattus norvegicus 57783 R-RNO-189384 https://reactome.org/PathwayBrowser/#/R-RNO-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Rattus norvegicus 57783 R-RNO-189398 https://reactome.org/PathwayBrowser/#/R-RNO-189398 HMOX1 dimer, HMOX2 cleave heme IEA Rattus norvegicus 57783 R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 57783 R-RNO-191352 https://reactome.org/PathwayBrowser/#/R-RNO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Rattus norvegicus 57783 R-RNO-191402 https://reactome.org/PathwayBrowser/#/R-RNO-191402 Reduction of presqualene diphosphate to form squalene IEA Rattus norvegicus 57783 R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 57783 R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 57783 R-RNO-191999 https://reactome.org/PathwayBrowser/#/R-RNO-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Rattus norvegicus 57783 R-RNO-192033 https://reactome.org/PathwayBrowser/#/R-RNO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Rattus norvegicus 57783 R-RNO-192036 https://reactome.org/PathwayBrowser/#/R-RNO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Rattus norvegicus 57783 R-RNO-192042 https://reactome.org/PathwayBrowser/#/R-RNO-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 57783 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 57783 R-RNO-192054 https://reactome.org/PathwayBrowser/#/R-RNO-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Rattus norvegicus 57783 R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 57783 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 57783 R-RNO-192067 https://reactome.org/PathwayBrowser/#/R-RNO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Rattus norvegicus 57783 R-RNO-192123 https://reactome.org/PathwayBrowser/#/R-RNO-192123 CYP27A1 27-hydroxylates CHOL IEA Rattus norvegicus 57783 R-RNO-192157 https://reactome.org/PathwayBrowser/#/R-RNO-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Rattus norvegicus 57783 R-RNO-192160 https://reactome.org/PathwayBrowser/#/R-RNO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Rattus norvegicus 57783 R-RNO-192178 https://reactome.org/PathwayBrowser/#/R-RNO-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Rattus norvegicus 57783 R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 57783 R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 57783 R-RNO-193064 https://reactome.org/PathwayBrowser/#/R-RNO-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Rattus norvegicus 57783 R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 57783 R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 57783 R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 57783 R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 57783 R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 57783 R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 57783 R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 57783 R-RNO-193393 https://reactome.org/PathwayBrowser/#/R-RNO-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Rattus norvegicus 57783 R-RNO-193460 https://reactome.org/PathwayBrowser/#/R-RNO-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Rattus norvegicus 57783 R-RNO-193497 https://reactome.org/PathwayBrowser/#/R-RNO-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Rattus norvegicus 57783 R-RNO-193709 https://reactome.org/PathwayBrowser/#/R-RNO-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Rattus norvegicus 57783 R-RNO-193713 https://reactome.org/PathwayBrowser/#/R-RNO-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Rattus norvegicus 57783 R-RNO-193719 https://reactome.org/PathwayBrowser/#/R-RNO-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 57783 R-RNO-193737 https://reactome.org/PathwayBrowser/#/R-RNO-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Rattus norvegicus 57783 R-RNO-193746 https://reactome.org/PathwayBrowser/#/R-RNO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 57783 R-RNO-193755 https://reactome.org/PathwayBrowser/#/R-RNO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Rattus norvegicus 57783 R-RNO-193758 https://reactome.org/PathwayBrowser/#/R-RNO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Rattus norvegicus 57783 R-RNO-193780 https://reactome.org/PathwayBrowser/#/R-RNO-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 57783 R-RNO-193781 https://reactome.org/PathwayBrowser/#/R-RNO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Rattus norvegicus 57783 R-RNO-193787 https://reactome.org/PathwayBrowser/#/R-RNO-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Rattus norvegicus 57783 R-RNO-193792 https://reactome.org/PathwayBrowser/#/R-RNO-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Rattus norvegicus 57783 R-RNO-193800 https://reactome.org/PathwayBrowser/#/R-RNO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Rattus norvegicus 57783 R-RNO-193821 https://reactome.org/PathwayBrowser/#/R-RNO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Rattus norvegicus 57783 R-RNO-193824 https://reactome.org/PathwayBrowser/#/R-RNO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Rattus norvegicus 57783 R-RNO-193841 https://reactome.org/PathwayBrowser/#/R-RNO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Rattus norvegicus 57783 R-RNO-193845 https://reactome.org/PathwayBrowser/#/R-RNO-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Rattus norvegicus 57783 R-RNO-193964 https://reactome.org/PathwayBrowser/#/R-RNO-193964 CYP21A2 21-hydroxylates PROG IEA Rattus norvegicus 57783 R-RNO-193965 https://reactome.org/PathwayBrowser/#/R-RNO-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Rattus norvegicus 57783 R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 57783 R-RNO-193995 https://reactome.org/PathwayBrowser/#/R-RNO-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Rattus norvegicus 57783 R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 57783 R-RNO-194017 https://reactome.org/PathwayBrowser/#/R-RNO-194017 CYP11B2 oxidises 11DCORST to CORST IEA Rattus norvegicus 57783 R-RNO-194023 https://reactome.org/PathwayBrowser/#/R-RNO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Rattus norvegicus 57783 R-RNO-194632 https://reactome.org/PathwayBrowser/#/R-RNO-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Rattus norvegicus 57783 R-RNO-194641 https://reactome.org/PathwayBrowser/#/R-RNO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 57783 R-RNO-194669 https://reactome.org/PathwayBrowser/#/R-RNO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 57783 R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 57783 R-RNO-194689 https://reactome.org/PathwayBrowser/#/R-RNO-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 57783 R-RNO-194698 https://reactome.org/PathwayBrowser/#/R-RNO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Rattus norvegicus 57783 R-RNO-195664 https://reactome.org/PathwayBrowser/#/R-RNO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Rattus norvegicus 57783 R-RNO-196060 https://reactome.org/PathwayBrowser/#/R-RNO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Rattus norvegicus 57783 R-RNO-196402 https://reactome.org/PathwayBrowser/#/R-RNO-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Rattus norvegicus 57783 R-RNO-196417 https://reactome.org/PathwayBrowser/#/R-RNO-196417 Reduction of desmosterol to cholesterol IEA Rattus norvegicus 57783 R-RNO-197963 https://reactome.org/PathwayBrowser/#/R-RNO-197963 DHFR2 reduces FOLA to DHF IEA Rattus norvegicus 57783 R-RNO-197972 https://reactome.org/PathwayBrowser/#/R-RNO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Rattus norvegicus 57783 R-RNO-200644 https://reactome.org/PathwayBrowser/#/R-RNO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Rattus norvegicus 57783 R-RNO-200676 https://reactome.org/PathwayBrowser/#/R-RNO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Rattus norvegicus 57783 R-RNO-200718 https://reactome.org/PathwayBrowser/#/R-RNO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Rattus norvegicus 57783 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 57783 R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 57783 R-RNO-209772 https://reactome.org/PathwayBrowser/#/R-RNO-209772 Thyroxine is deiodinated to triiodothyronine IEA Rattus norvegicus 57783 R-RNO-209845 https://reactome.org/PathwayBrowser/#/R-RNO-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Rattus norvegicus 57783 R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 57783 R-RNO-211873 https://reactome.org/PathwayBrowser/#/R-RNO-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Rattus norvegicus 57783 R-RNO-211923 https://reactome.org/PathwayBrowser/#/R-RNO-211923 CYP26C1 4-hydroxylates 9cRA IEA Rattus norvegicus 57783 R-RNO-211950 https://reactome.org/PathwayBrowser/#/R-RNO-211950 CYP24A1 24-hydroxylates CTL IEA Rattus norvegicus 57783 R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 57783 R-RNO-2161549 https://reactome.org/PathwayBrowser/#/R-RNO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Rattus norvegicus 57783 R-RNO-2161614 https://reactome.org/PathwayBrowser/#/R-RNO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Rattus norvegicus 57783 R-RNO-2161651 https://reactome.org/PathwayBrowser/#/R-RNO-2161651 PGE2 is converted to PGF2a by CBR1 IEA Rattus norvegicus 57783 R-RNO-2161745 https://reactome.org/PathwayBrowser/#/R-RNO-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 57783 R-RNO-2161792 https://reactome.org/PathwayBrowser/#/R-RNO-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 57783 R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus 57783 R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Rattus norvegicus 57783 R-RNO-2161951 https://reactome.org/PathwayBrowser/#/R-RNO-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Rattus norvegicus 57783 R-RNO-2395517 https://reactome.org/PathwayBrowser/#/R-RNO-2395517 NADPH transfers electrons to FDXR IEA Rattus norvegicus 57783 R-RNO-2408514 https://reactome.org/PathwayBrowser/#/R-RNO-2408514 GSSeSG is reduced to GSSeH and GSH by Gsr TAS Rattus norvegicus 57783 R-RNO-2464822 https://reactome.org/PathwayBrowser/#/R-RNO-2464822 RDH12 reduces atRAL to atROL IEA Rattus norvegicus 57783 R-RNO-2465940 https://reactome.org/PathwayBrowser/#/R-RNO-2465940 atRAL is reduced to atROL IEA Rattus norvegicus 57783 R-RNO-2855252 https://reactome.org/PathwayBrowser/#/R-RNO-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 57783 R-RNO-3149518 https://reactome.org/PathwayBrowser/#/R-RNO-3149518 MTRR reduces cob(II)alamin to meCbl IEA Rattus norvegicus 57783 R-RNO-3149519 https://reactome.org/PathwayBrowser/#/R-RNO-3149519 MMACHC decyanates CNCbl IEA Rattus norvegicus 57783 R-RNO-3323050 https://reactome.org/PathwayBrowser/#/R-RNO-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Rattus norvegicus 57783 R-RNO-3323079 https://reactome.org/PathwayBrowser/#/R-RNO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 57783 R-RNO-350869 https://reactome.org/PathwayBrowser/#/R-RNO-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Rattus norvegicus 57783 R-RNO-389540 https://reactome.org/PathwayBrowser/#/R-RNO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 57783 R-RNO-390425 https://reactome.org/PathwayBrowser/#/R-RNO-390425 FAR1 reduces PalmCoA to HXOL IEA Rattus norvegicus 57783 R-RNO-390438 https://reactome.org/PathwayBrowser/#/R-RNO-390438 FAR2 reduces PalmCoA to HXOL IEA Rattus norvegicus 57783 R-RNO-418436 https://reactome.org/PathwayBrowser/#/R-RNO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Rattus norvegicus 57783 R-RNO-428123 https://reactome.org/PathwayBrowser/#/R-RNO-428123 KDSR reduces 3-ketosphingoid IEA Rattus norvegicus 57783 R-RNO-4419979 https://reactome.org/PathwayBrowser/#/R-RNO-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Rattus norvegicus 57783 R-RNO-450971 https://reactome.org/PathwayBrowser/#/R-RNO-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Rattus norvegicus 57783 R-RNO-450984 https://reactome.org/PathwayBrowser/#/R-RNO-450984 IDH2 dimer decarboxylates isocitrate IEA Rattus norvegicus 57783 R-RNO-469659 https://reactome.org/PathwayBrowser/#/R-RNO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 57783 R-RNO-508040 https://reactome.org/PathwayBrowser/#/R-RNO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Rattus norvegicus 57783 R-RNO-514604 https://reactome.org/PathwayBrowser/#/R-RNO-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Rattus norvegicus 57783 R-RNO-5218841 https://reactome.org/PathwayBrowser/#/R-RNO-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Rattus norvegicus 57783 R-RNO-5263614 https://reactome.org/PathwayBrowser/#/R-RNO-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Rattus norvegicus 57783 R-RNO-5263616 https://reactome.org/PathwayBrowser/#/R-RNO-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Rattus norvegicus 57783 R-RNO-5340226 https://reactome.org/PathwayBrowser/#/R-RNO-5340226 CYGB dioxygenates NO IEA Rattus norvegicus 57783 R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 57783 R-RNO-5419165 https://reactome.org/PathwayBrowser/#/R-RNO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Rattus norvegicus 57783 R-RNO-5423637 https://reactome.org/PathwayBrowser/#/R-RNO-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Rattus norvegicus 57783 R-RNO-5423647 https://reactome.org/PathwayBrowser/#/R-RNO-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Rattus norvegicus 57783 R-RNO-5423664 https://reactome.org/PathwayBrowser/#/R-RNO-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Rattus norvegicus 57783 R-RNO-5423672 https://reactome.org/PathwayBrowser/#/R-RNO-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Rattus norvegicus 57783 R-RNO-5423678 https://reactome.org/PathwayBrowser/#/R-RNO-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Rattus norvegicus 57783 R-RNO-548818 https://reactome.org/PathwayBrowser/#/R-RNO-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Rattus norvegicus 57783 R-RNO-548831 https://reactome.org/PathwayBrowser/#/R-RNO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Rattus norvegicus 57783 R-RNO-5615668 https://reactome.org/PathwayBrowser/#/R-RNO-5615668 AKR1C3 reduces atRAL to atROL IEA Rattus norvegicus 57783 R-RNO-5652172 https://reactome.org/PathwayBrowser/#/R-RNO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Rattus norvegicus 57783 R-RNO-5661240 https://reactome.org/PathwayBrowser/#/R-RNO-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Rattus norvegicus 57783 R-RNO-5661256 https://reactome.org/PathwayBrowser/#/R-RNO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Rattus norvegicus 57783 R-RNO-5668629 https://reactome.org/PathwayBrowser/#/R-RNO-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Rattus norvegicus 57783 R-RNO-5668718 https://reactome.org/PathwayBrowser/#/R-RNO-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 57783 R-RNO-5668731 https://reactome.org/PathwayBrowser/#/R-RNO-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 57783 R-RNO-5692232 https://reactome.org/PathwayBrowser/#/R-RNO-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Rattus norvegicus 57783 R-RNO-5692283 https://reactome.org/PathwayBrowser/#/R-RNO-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Rattus norvegicus 57783 R-RNO-5693390 https://reactome.org/PathwayBrowser/#/R-RNO-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Rattus norvegicus 57783 R-RNO-5696822 https://reactome.org/PathwayBrowser/#/R-RNO-5696822 AKR1B15 reduces EST17b to E1 IEA Rattus norvegicus 57783 R-RNO-6783955 https://reactome.org/PathwayBrowser/#/R-RNO-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 57783 R-RNO-6786239 https://reactome.org/PathwayBrowser/#/R-RNO-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Rattus norvegicus 57783 R-RNO-6787642 https://reactome.org/PathwayBrowser/#/R-RNO-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Rattus norvegicus 57783 R-RNO-6789092 https://reactome.org/PathwayBrowser/#/R-RNO-6789092 NOX2 generates superoxide anion from oxygen IEA Rattus norvegicus 57783 R-RNO-6806967 https://reactome.org/PathwayBrowser/#/R-RNO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Rattus norvegicus 57783 R-RNO-6807053 https://reactome.org/PathwayBrowser/#/R-RNO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Rattus norvegicus 57783 R-RNO-6807055 https://reactome.org/PathwayBrowser/#/R-RNO-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Rattus norvegicus 57783 R-RNO-6807064 https://reactome.org/PathwayBrowser/#/R-RNO-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Rattus norvegicus 57783 R-RNO-6807557 https://reactome.org/PathwayBrowser/#/R-RNO-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Rattus norvegicus 57783 R-RNO-6808487 https://reactome.org/PathwayBrowser/#/R-RNO-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 57783 R-RNO-6808496 https://reactome.org/PathwayBrowser/#/R-RNO-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 57783 R-RNO-6810594 https://reactome.org/PathwayBrowser/#/R-RNO-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 57783 R-RNO-70377 https://reactome.org/PathwayBrowser/#/R-RNO-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Rattus norvegicus 57783 R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Rattus norvegicus 57783 R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Rattus norvegicus 57783 R-RNO-70938 https://reactome.org/PathwayBrowser/#/R-RNO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Rattus norvegicus 57783 R-RNO-71200 https://reactome.org/PathwayBrowser/#/R-RNO-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Rattus norvegicus 57783 R-RNO-71299 https://reactome.org/PathwayBrowser/#/R-RNO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Rattus norvegicus 57783 R-RNO-71682 https://reactome.org/PathwayBrowser/#/R-RNO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 57783 R-RNO-73585 https://reactome.org/PathwayBrowser/#/R-RNO-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Rattus norvegicus 57783 R-RNO-73616 https://reactome.org/PathwayBrowser/#/R-RNO-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Rattus norvegicus 57783 R-RNO-73646 https://reactome.org/PathwayBrowser/#/R-RNO-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Rattus norvegicus 57783 R-RNO-74872 https://reactome.org/PathwayBrowser/#/R-RNO-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 57783 R-RNO-75872 https://reactome.org/PathwayBrowser/#/R-RNO-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Rattus norvegicus 57783 R-RNO-75883 https://reactome.org/PathwayBrowser/#/R-RNO-75883 DHRS7B reduces GO3P to HXDG3P IEA Rattus norvegicus 57783 R-RNO-804969 https://reactome.org/PathwayBrowser/#/R-RNO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Rattus norvegicus 57783 R-RNO-8862137 https://reactome.org/PathwayBrowser/#/R-RNO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 57783 R-RNO-8862152 https://reactome.org/PathwayBrowser/#/R-RNO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Rattus norvegicus 57783 R-RNO-8937419 https://reactome.org/PathwayBrowser/#/R-RNO-8937419 CBR3 reduces DOX to DOXOL IEA Rattus norvegicus 57783 R-RNO-8952873 https://reactome.org/PathwayBrowser/#/R-RNO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Rattus norvegicus 57783 R-RNO-9012036 https://reactome.org/PathwayBrowser/#/R-RNO-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 57783 R-RNO-9012349 https://reactome.org/PathwayBrowser/#/R-RNO-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 57783 R-RNO-9020255 https://reactome.org/PathwayBrowser/#/R-RNO-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Rattus norvegicus 57783 R-RNO-9020256 https://reactome.org/PathwayBrowser/#/R-RNO-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Rattus norvegicus 57783 R-RNO-9020262 https://reactome.org/PathwayBrowser/#/R-RNO-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Rattus norvegicus 57783 R-RNO-9020277 https://reactome.org/PathwayBrowser/#/R-RNO-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Rattus norvegicus 57783 R-RNO-9020278 https://reactome.org/PathwayBrowser/#/R-RNO-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Rattus norvegicus 57783 R-RNO-9024881 https://reactome.org/PathwayBrowser/#/R-RNO-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Rattus norvegicus 57783 R-RNO-9024983 https://reactome.org/PathwayBrowser/#/R-RNO-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Rattus norvegicus 57783 R-RNO-9025995 https://reactome.org/PathwayBrowser/#/R-RNO-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Rattus norvegicus 57783 R-RNO-9025999 https://reactome.org/PathwayBrowser/#/R-RNO-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Rattus norvegicus 57783 R-RNO-9026007 https://reactome.org/PathwayBrowser/#/R-RNO-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Rattus norvegicus 57783 R-RNO-9027043 https://reactome.org/PathwayBrowser/#/R-RNO-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Rattus norvegicus 57783 R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 57783 R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 57783 R-RNO-9037761 https://reactome.org/PathwayBrowser/#/R-RNO-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Rattus norvegicus 57783 R-RNO-917811 https://reactome.org/PathwayBrowser/#/R-RNO-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Rattus norvegicus 57783 R-RNO-9705713 https://reactome.org/PathwayBrowser/#/R-RNO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 57783 R-RNO-9705714 https://reactome.org/PathwayBrowser/#/R-RNO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 57783 R-RNO-9709098 https://reactome.org/PathwayBrowser/#/R-RNO-9709098 DHFR dimer reduces FOLA to DHF IEA Rattus norvegicus 57783 R-RNO-9753285 https://reactome.org/PathwayBrowser/#/R-RNO-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Rattus norvegicus 57783 R-RNO-9755937 https://reactome.org/PathwayBrowser/#/R-RNO-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Rattus norvegicus 57783 R-RNO-9756138 https://reactome.org/PathwayBrowser/#/R-RNO-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Rattus norvegicus 57783 R-RNO-9756162 https://reactome.org/PathwayBrowser/#/R-RNO-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Rattus norvegicus 57783 R-RNO-9756169 https://reactome.org/PathwayBrowser/#/R-RNO-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Rattus norvegicus 57783 R-RNO-9756180 https://reactome.org/PathwayBrowser/#/R-RNO-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Rattus norvegicus 57783 R-RNO-975629 https://reactome.org/PathwayBrowser/#/R-RNO-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 57783 R-RNO-9757706 https://reactome.org/PathwayBrowser/#/R-RNO-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Rattus norvegicus 57783 R-RNO-9758682 https://reactome.org/PathwayBrowser/#/R-RNO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Rattus norvegicus 57783 R-RNO-9759259 https://reactome.org/PathwayBrowser/#/R-RNO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Rattus norvegicus 57783 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 57783 R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 57783 R-SCE-191352 https://reactome.org/PathwayBrowser/#/R-SCE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Saccharomyces cerevisiae 57783 R-SCE-191402 https://reactome.org/PathwayBrowser/#/R-SCE-191402 Reduction of presqualene diphosphate to form squalene IEA Saccharomyces cerevisiae 57783 R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 57783 R-SCE-192033 https://reactome.org/PathwayBrowser/#/R-SCE-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Saccharomyces cerevisiae 57783 R-SCE-192036 https://reactome.org/PathwayBrowser/#/R-SCE-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Saccharomyces cerevisiae 57783 R-SCE-192067 https://reactome.org/PathwayBrowser/#/R-SCE-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Saccharomyces cerevisiae 57783 R-SCE-192160 https://reactome.org/PathwayBrowser/#/R-SCE-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Saccharomyces cerevisiae 57783 R-SCE-193746 https://reactome.org/PathwayBrowser/#/R-SCE-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Saccharomyces cerevisiae 57783 R-SCE-193755 https://reactome.org/PathwayBrowser/#/R-SCE-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Saccharomyces cerevisiae 57783 R-SCE-193758 https://reactome.org/PathwayBrowser/#/R-SCE-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Saccharomyces cerevisiae 57783 R-SCE-193781 https://reactome.org/PathwayBrowser/#/R-SCE-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Saccharomyces cerevisiae 57783 R-SCE-193800 https://reactome.org/PathwayBrowser/#/R-SCE-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Saccharomyces cerevisiae 57783 R-SCE-193821 https://reactome.org/PathwayBrowser/#/R-SCE-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Saccharomyces cerevisiae 57783 R-SCE-193824 https://reactome.org/PathwayBrowser/#/R-SCE-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Saccharomyces cerevisiae 57783 R-SCE-193841 https://reactome.org/PathwayBrowser/#/R-SCE-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Saccharomyces cerevisiae 57783 R-SCE-194641 https://reactome.org/PathwayBrowser/#/R-SCE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 57783 R-SCE-194669 https://reactome.org/PathwayBrowser/#/R-SCE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 57783 R-SCE-194678 https://reactome.org/PathwayBrowser/#/R-SCE-194678 CYP51A1 demethylates LNSOL IEA Saccharomyces cerevisiae 57783 R-SCE-194698 https://reactome.org/PathwayBrowser/#/R-SCE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Saccharomyces cerevisiae 57783 R-SCE-195664 https://reactome.org/PathwayBrowser/#/R-SCE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Saccharomyces cerevisiae 57783 R-SCE-196060 https://reactome.org/PathwayBrowser/#/R-SCE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Saccharomyces cerevisiae 57783 R-SCE-197963 https://reactome.org/PathwayBrowser/#/R-SCE-197963 DHFR2 reduces FOLA to DHF IEA Saccharomyces cerevisiae 57783 R-SCE-197972 https://reactome.org/PathwayBrowser/#/R-SCE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Saccharomyces cerevisiae 57783 R-SCE-200644 https://reactome.org/PathwayBrowser/#/R-SCE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Saccharomyces cerevisiae 57783 R-SCE-200676 https://reactome.org/PathwayBrowser/#/R-SCE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Saccharomyces cerevisiae 57783 R-SCE-200718 https://reactome.org/PathwayBrowser/#/R-SCE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Saccharomyces cerevisiae 57783 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 57783 R-SCE-2161549 https://reactome.org/PathwayBrowser/#/R-SCE-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Saccharomyces cerevisiae 57783 R-SCE-2161614 https://reactome.org/PathwayBrowser/#/R-SCE-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Saccharomyces cerevisiae 57783 R-SCE-2164813 https://reactome.org/PathwayBrowser/#/R-SCE-2164813 HMPhOH is hydroxylated to MDMQ6H2 by HMPhOH monooxygenase TAS Saccharomyces cerevisiae 57783 R-SCE-2395517 https://reactome.org/PathwayBrowser/#/R-SCE-2395517 NADPH transfers electrons to FDXR IEA Saccharomyces cerevisiae 57783 R-SCE-2408518 https://reactome.org/PathwayBrowser/#/R-SCE-2408518 PAPSe is reduced to SeO3(2-) by MET16 TAS Saccharomyces cerevisiae 57783 R-SCE-2465940 https://reactome.org/PathwayBrowser/#/R-SCE-2465940 atRAL is reduced to atROL IEA Saccharomyces cerevisiae 57783 R-SCE-2564819 https://reactome.org/PathwayBrowser/#/R-SCE-2564819 NADPH reduces TAH18:DRE2 TAS Saccharomyces cerevisiae 57783 R-SCE-3323079 https://reactome.org/PathwayBrowser/#/R-SCE-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 57783 R-SCE-389540 https://reactome.org/PathwayBrowser/#/R-SCE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 57783 R-SCE-418436 https://reactome.org/PathwayBrowser/#/R-SCE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Saccharomyces cerevisiae 57783 R-SCE-428123 https://reactome.org/PathwayBrowser/#/R-SCE-428123 KDSR reduces 3-ketosphingoid IEA Saccharomyces cerevisiae 57783 R-SCE-4419979 https://reactome.org/PathwayBrowser/#/R-SCE-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Saccharomyces cerevisiae 57783 R-SCE-508040 https://reactome.org/PathwayBrowser/#/R-SCE-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Saccharomyces cerevisiae 57783 R-SCE-5419165 https://reactome.org/PathwayBrowser/#/R-SCE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Saccharomyces cerevisiae 57783 R-SCE-548831 https://reactome.org/PathwayBrowser/#/R-SCE-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Saccharomyces cerevisiae 57783 R-SCE-5615668 https://reactome.org/PathwayBrowser/#/R-SCE-5615668 AKR1C3 reduces atRAL to atROL IEA Saccharomyces cerevisiae 57783 R-SCE-5652172 https://reactome.org/PathwayBrowser/#/R-SCE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Saccharomyces cerevisiae 57783 R-SCE-5661256 https://reactome.org/PathwayBrowser/#/R-SCE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Saccharomyces cerevisiae 57783 R-SCE-5692232 https://reactome.org/PathwayBrowser/#/R-SCE-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Saccharomyces cerevisiae 57783 R-SCE-5692283 https://reactome.org/PathwayBrowser/#/R-SCE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Saccharomyces cerevisiae 57783 R-SCE-5693390 https://reactome.org/PathwayBrowser/#/R-SCE-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Saccharomyces cerevisiae 57783 R-SCE-5696822 https://reactome.org/PathwayBrowser/#/R-SCE-5696822 AKR1B15 reduces EST17b to E1 IEA Saccharomyces cerevisiae 57783 R-SCE-6783955 https://reactome.org/PathwayBrowser/#/R-SCE-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 57783 R-SCE-6806967 https://reactome.org/PathwayBrowser/#/R-SCE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Saccharomyces cerevisiae 57783 R-SCE-6807053 https://reactome.org/PathwayBrowser/#/R-SCE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Saccharomyces cerevisiae 57783 R-SCE-6807557 https://reactome.org/PathwayBrowser/#/R-SCE-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Saccharomyces cerevisiae 57783 R-SCE-70377 https://reactome.org/PathwayBrowser/#/R-SCE-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Saccharomyces cerevisiae 57783 R-SCE-70938 https://reactome.org/PathwayBrowser/#/R-SCE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Saccharomyces cerevisiae 57783 R-SCE-71200 https://reactome.org/PathwayBrowser/#/R-SCE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Saccharomyces cerevisiae 57783 R-SCE-71299 https://reactome.org/PathwayBrowser/#/R-SCE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 57783 R-SCE-71682 https://reactome.org/PathwayBrowser/#/R-SCE-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 57783 R-SCE-8862152 https://reactome.org/PathwayBrowser/#/R-SCE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Saccharomyces cerevisiae 57783 R-SCE-8952873 https://reactome.org/PathwayBrowser/#/R-SCE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Saccharomyces cerevisiae 57783 R-SCE-9705714 https://reactome.org/PathwayBrowser/#/R-SCE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Saccharomyces cerevisiae 57783 R-SCE-9709098 https://reactome.org/PathwayBrowser/#/R-SCE-9709098 DHFR dimer reduces FOLA to DHF IEA Saccharomyces cerevisiae 57783 R-SCE-9758682 https://reactome.org/PathwayBrowser/#/R-SCE-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Saccharomyces cerevisiae 57783 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 57783 R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 57783 R-SPO-191352 https://reactome.org/PathwayBrowser/#/R-SPO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Schizosaccharomyces pombe 57783 R-SPO-191402 https://reactome.org/PathwayBrowser/#/R-SPO-191402 Reduction of presqualene diphosphate to form squalene IEA Schizosaccharomyces pombe 57783 R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 57783 R-SPO-192033 https://reactome.org/PathwayBrowser/#/R-SPO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Schizosaccharomyces pombe 57783 R-SPO-192036 https://reactome.org/PathwayBrowser/#/R-SPO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Schizosaccharomyces pombe 57783 R-SPO-192067 https://reactome.org/PathwayBrowser/#/R-SPO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Schizosaccharomyces pombe 57783 R-SPO-192160 https://reactome.org/PathwayBrowser/#/R-SPO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Schizosaccharomyces pombe 57783 R-SPO-193746 https://reactome.org/PathwayBrowser/#/R-SPO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Schizosaccharomyces pombe 57783 R-SPO-193755 https://reactome.org/PathwayBrowser/#/R-SPO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Schizosaccharomyces pombe 57783 R-SPO-193758 https://reactome.org/PathwayBrowser/#/R-SPO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Schizosaccharomyces pombe 57783 R-SPO-193781 https://reactome.org/PathwayBrowser/#/R-SPO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Schizosaccharomyces pombe 57783 R-SPO-193800 https://reactome.org/PathwayBrowser/#/R-SPO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Schizosaccharomyces pombe 57783 R-SPO-193821 https://reactome.org/PathwayBrowser/#/R-SPO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Schizosaccharomyces pombe 57783 R-SPO-193824 https://reactome.org/PathwayBrowser/#/R-SPO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Schizosaccharomyces pombe 57783 R-SPO-193841 https://reactome.org/PathwayBrowser/#/R-SPO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Schizosaccharomyces pombe 57783 R-SPO-194023 https://reactome.org/PathwayBrowser/#/R-SPO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Schizosaccharomyces pombe 57783 R-SPO-194641 https://reactome.org/PathwayBrowser/#/R-SPO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 57783 R-SPO-194669 https://reactome.org/PathwayBrowser/#/R-SPO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 57783 R-SPO-194678 https://reactome.org/PathwayBrowser/#/R-SPO-194678 CYP51A1 demethylates LNSOL IEA Schizosaccharomyces pombe 57783 R-SPO-194698 https://reactome.org/PathwayBrowser/#/R-SPO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Schizosaccharomyces pombe 57783 R-SPO-195664 https://reactome.org/PathwayBrowser/#/R-SPO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Schizosaccharomyces pombe 57783 R-SPO-196060 https://reactome.org/PathwayBrowser/#/R-SPO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Schizosaccharomyces pombe 57783 R-SPO-197963 https://reactome.org/PathwayBrowser/#/R-SPO-197963 DHFR2 reduces FOLA to DHF IEA Schizosaccharomyces pombe 57783 R-SPO-197972 https://reactome.org/PathwayBrowser/#/R-SPO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Schizosaccharomyces pombe 57783 R-SPO-200644 https://reactome.org/PathwayBrowser/#/R-SPO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Schizosaccharomyces pombe 57783 R-SPO-200676 https://reactome.org/PathwayBrowser/#/R-SPO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Schizosaccharomyces pombe 57783 R-SPO-200718 https://reactome.org/PathwayBrowser/#/R-SPO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Schizosaccharomyces pombe 57783 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 57783 R-SPO-2161549 https://reactome.org/PathwayBrowser/#/R-SPO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Schizosaccharomyces pombe 57783 R-SPO-2161614 https://reactome.org/PathwayBrowser/#/R-SPO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Schizosaccharomyces pombe 57783 R-SPO-2395517 https://reactome.org/PathwayBrowser/#/R-SPO-2395517 NADPH transfers electrons to FDXR IEA Schizosaccharomyces pombe 57783 R-SPO-3323079 https://reactome.org/PathwayBrowser/#/R-SPO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 57783 R-SPO-389540 https://reactome.org/PathwayBrowser/#/R-SPO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 57783 R-SPO-418436 https://reactome.org/PathwayBrowser/#/R-SPO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Schizosaccharomyces pombe 57783 R-SPO-428123 https://reactome.org/PathwayBrowser/#/R-SPO-428123 KDSR reduces 3-ketosphingoid IEA Schizosaccharomyces pombe 57783 R-SPO-4419979 https://reactome.org/PathwayBrowser/#/R-SPO-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Schizosaccharomyces pombe 57783 R-SPO-469659 https://reactome.org/PathwayBrowser/#/R-SPO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 57783 R-SPO-508040 https://reactome.org/PathwayBrowser/#/R-SPO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Schizosaccharomyces pombe 57783 R-SPO-5419165 https://reactome.org/PathwayBrowser/#/R-SPO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Schizosaccharomyces pombe 57783 R-SPO-548831 https://reactome.org/PathwayBrowser/#/R-SPO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Schizosaccharomyces pombe 57783 R-SPO-5615668 https://reactome.org/PathwayBrowser/#/R-SPO-5615668 AKR1C3 reduces atRAL to atROL IEA Schizosaccharomyces pombe 57783 R-SPO-5652172 https://reactome.org/PathwayBrowser/#/R-SPO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Schizosaccharomyces pombe 57783 R-SPO-5661256 https://reactome.org/PathwayBrowser/#/R-SPO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Schizosaccharomyces pombe 57783 R-SPO-5692232 https://reactome.org/PathwayBrowser/#/R-SPO-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Schizosaccharomyces pombe 57783 R-SPO-5696822 https://reactome.org/PathwayBrowser/#/R-SPO-5696822 AKR1B15 reduces EST17b to E1 IEA Schizosaccharomyces pombe 57783 R-SPO-6783955 https://reactome.org/PathwayBrowser/#/R-SPO-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 57783 R-SPO-6806967 https://reactome.org/PathwayBrowser/#/R-SPO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Schizosaccharomyces pombe 57783 R-SPO-6807053 https://reactome.org/PathwayBrowser/#/R-SPO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Schizosaccharomyces pombe 57783 R-SPO-70377 https://reactome.org/PathwayBrowser/#/R-SPO-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Schizosaccharomyces pombe 57783 R-SPO-70938 https://reactome.org/PathwayBrowser/#/R-SPO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Schizosaccharomyces pombe 57783 R-SPO-71299 https://reactome.org/PathwayBrowser/#/R-SPO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 57783 R-SPO-71682 https://reactome.org/PathwayBrowser/#/R-SPO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 57783 R-SPO-804969 https://reactome.org/PathwayBrowser/#/R-SPO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Schizosaccharomyces pombe 57783 R-SPO-8862137 https://reactome.org/PathwayBrowser/#/R-SPO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Schizosaccharomyces pombe 57783 R-SPO-8862152 https://reactome.org/PathwayBrowser/#/R-SPO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Schizosaccharomyces pombe 57783 R-SPO-8952873 https://reactome.org/PathwayBrowser/#/R-SPO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Schizosaccharomyces pombe 57783 R-SPO-9705713 https://reactome.org/PathwayBrowser/#/R-SPO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 57783 R-SPO-9705714 https://reactome.org/PathwayBrowser/#/R-SPO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 57783 R-SPO-9709098 https://reactome.org/PathwayBrowser/#/R-SPO-9709098 DHFR dimer reduces FOLA to DHF IEA Schizosaccharomyces pombe 57783 R-SPO-9758682 https://reactome.org/PathwayBrowser/#/R-SPO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Schizosaccharomyces pombe 57783 R-SPO-9759259 https://reactome.org/PathwayBrowser/#/R-SPO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Schizosaccharomyces pombe 57783 R-SSC-1222376 https://reactome.org/PathwayBrowser/#/R-SSC-1222376 NOX2 generates superoxide from oxygen IEA Sus scrofa 57783 R-SSC-1475414 https://reactome.org/PathwayBrowser/#/R-SSC-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Sus scrofa 57783 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 57783 R-SSC-1497869 https://reactome.org/PathwayBrowser/#/R-SSC-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Sus scrofa 57783 R-SSC-156526 https://reactome.org/PathwayBrowser/#/R-SSC-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Sus scrofa 57783 R-SSC-1655453 https://reactome.org/PathwayBrowser/#/R-SSC-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Sus scrofa 57783 R-SSC-189384 https://reactome.org/PathwayBrowser/#/R-SSC-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Sus scrofa 57783 R-SSC-189398 https://reactome.org/PathwayBrowser/#/R-SSC-189398 HMOX1 dimer, HMOX2 cleave heme IEA Sus scrofa 57783 R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 57783 R-SSC-191352 https://reactome.org/PathwayBrowser/#/R-SSC-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Sus scrofa 57783 R-SSC-191402 https://reactome.org/PathwayBrowser/#/R-SSC-191402 Reduction of presqualene diphosphate to form squalene IEA Sus scrofa 57783 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 57783 R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 57783 R-SSC-191999 https://reactome.org/PathwayBrowser/#/R-SSC-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Sus scrofa 57783 R-SSC-192033 https://reactome.org/PathwayBrowser/#/R-SSC-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Sus scrofa 57783 R-SSC-192036 https://reactome.org/PathwayBrowser/#/R-SSC-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Sus scrofa 57783 R-SSC-192042 https://reactome.org/PathwayBrowser/#/R-SSC-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 57783 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 57783 R-SSC-192054 https://reactome.org/PathwayBrowser/#/R-SSC-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Sus scrofa 57783 R-SSC-192061 https://reactome.org/PathwayBrowser/#/R-SSC-192061 CYP46A1 24-hydroxylates CHOL IEA Sus scrofa 57783 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 57783 R-SSC-192067 https://reactome.org/PathwayBrowser/#/R-SSC-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Sus scrofa 57783 R-SSC-192123 https://reactome.org/PathwayBrowser/#/R-SSC-192123 CYP27A1 27-hydroxylates CHOL IEA Sus scrofa 57783 R-SSC-192157 https://reactome.org/PathwayBrowser/#/R-SSC-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Sus scrofa 57783 R-SSC-192160 https://reactome.org/PathwayBrowser/#/R-SSC-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Sus scrofa 57783 R-SSC-192178 https://reactome.org/PathwayBrowser/#/R-SSC-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Sus scrofa 57783 R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 57783 R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 57783 R-SSC-193064 https://reactome.org/PathwayBrowser/#/R-SSC-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Sus scrofa 57783 R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 57783 R-SSC-193068 https://reactome.org/PathwayBrowser/#/R-SSC-193068 CYP17A1 17-hydroxylates PREG IEA Sus scrofa 57783 R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 57783 R-SSC-193072 https://reactome.org/PathwayBrowser/#/R-SSC-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Sus scrofa 57783 R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 57783 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 57783 R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 57783 R-SSC-193393 https://reactome.org/PathwayBrowser/#/R-SSC-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Sus scrofa 57783 R-SSC-193460 https://reactome.org/PathwayBrowser/#/R-SSC-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Sus scrofa 57783 R-SSC-193497 https://reactome.org/PathwayBrowser/#/R-SSC-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Sus scrofa 57783 R-SSC-193709 https://reactome.org/PathwayBrowser/#/R-SSC-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Sus scrofa 57783 R-SSC-193713 https://reactome.org/PathwayBrowser/#/R-SSC-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Sus scrofa 57783 R-SSC-193719 https://reactome.org/PathwayBrowser/#/R-SSC-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 57783 R-SSC-193737 https://reactome.org/PathwayBrowser/#/R-SSC-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Sus scrofa 57783 R-SSC-193746 https://reactome.org/PathwayBrowser/#/R-SSC-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Sus scrofa 57783 R-SSC-193755 https://reactome.org/PathwayBrowser/#/R-SSC-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Sus scrofa 57783 R-SSC-193758 https://reactome.org/PathwayBrowser/#/R-SSC-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Sus scrofa 57783 R-SSC-193780 https://reactome.org/PathwayBrowser/#/R-SSC-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Sus scrofa 57783 R-SSC-193781 https://reactome.org/PathwayBrowser/#/R-SSC-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Sus scrofa 57783 R-SSC-193787 https://reactome.org/PathwayBrowser/#/R-SSC-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Sus scrofa 57783 R-SSC-193792 https://reactome.org/PathwayBrowser/#/R-SSC-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Sus scrofa 57783 R-SSC-193800 https://reactome.org/PathwayBrowser/#/R-SSC-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Sus scrofa 57783 R-SSC-193821 https://reactome.org/PathwayBrowser/#/R-SSC-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Sus scrofa 57783 R-SSC-193824 https://reactome.org/PathwayBrowser/#/R-SSC-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Sus scrofa 57783 R-SSC-193841 https://reactome.org/PathwayBrowser/#/R-SSC-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Sus scrofa 57783 R-SSC-193845 https://reactome.org/PathwayBrowser/#/R-SSC-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Sus scrofa 57783 R-SSC-193964 https://reactome.org/PathwayBrowser/#/R-SSC-193964 CYP21A2 21-hydroxylates PROG IEA Sus scrofa 57783 R-SSC-193965 https://reactome.org/PathwayBrowser/#/R-SSC-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Sus scrofa 57783 R-SSC-193981 https://reactome.org/PathwayBrowser/#/R-SSC-193981 CYP21A2 oxidises 17HPROG IEA Sus scrofa 57783 R-SSC-193995 https://reactome.org/PathwayBrowser/#/R-SSC-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Sus scrofa 57783 R-SSC-193997 https://reactome.org/PathwayBrowser/#/R-SSC-193997 CYP11B1 oxidises 11DCORT IEA Sus scrofa 57783 R-SSC-194017 https://reactome.org/PathwayBrowser/#/R-SSC-194017 CYP11B2 oxidises 11DCORST to CORST IEA Sus scrofa 57783 R-SSC-194023 https://reactome.org/PathwayBrowser/#/R-SSC-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Sus scrofa 57783 R-SSC-194632 https://reactome.org/PathwayBrowser/#/R-SSC-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Sus scrofa 57783 R-SSC-194641 https://reactome.org/PathwayBrowser/#/R-SSC-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 57783 R-SSC-194669 https://reactome.org/PathwayBrowser/#/R-SSC-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 57783 R-SSC-194678 https://reactome.org/PathwayBrowser/#/R-SSC-194678 CYP51A1 demethylates LNSOL IEA Sus scrofa 57783 R-SSC-194689 https://reactome.org/PathwayBrowser/#/R-SSC-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 57783 R-SSC-194698 https://reactome.org/PathwayBrowser/#/R-SSC-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Sus scrofa 57783 R-SSC-195664 https://reactome.org/PathwayBrowser/#/R-SSC-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Sus scrofa 57783 R-SSC-196060 https://reactome.org/PathwayBrowser/#/R-SSC-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Sus scrofa 57783 R-SSC-196402 https://reactome.org/PathwayBrowser/#/R-SSC-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Sus scrofa 57783 R-SSC-196417 https://reactome.org/PathwayBrowser/#/R-SSC-196417 Reduction of desmosterol to cholesterol IEA Sus scrofa 57783 R-SSC-197963 https://reactome.org/PathwayBrowser/#/R-SSC-197963 DHFR2 reduces FOLA to DHF IEA Sus scrofa 57783 R-SSC-197972 https://reactome.org/PathwayBrowser/#/R-SSC-197972 DHF is reduced to tetrahydrofolate (THF) IEA Sus scrofa 57783 R-SSC-200644 https://reactome.org/PathwayBrowser/#/R-SSC-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Sus scrofa 57783 R-SSC-200676 https://reactome.org/PathwayBrowser/#/R-SSC-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Sus scrofa 57783 R-SSC-200718 https://reactome.org/PathwayBrowser/#/R-SSC-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Sus scrofa 57783 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 57783 R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 57783 R-SSC-209772 https://reactome.org/PathwayBrowser/#/R-SSC-209772 Thyroxine is deiodinated to triiodothyronine IEA Sus scrofa 57783 R-SSC-209845 https://reactome.org/PathwayBrowser/#/R-SSC-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Sus scrofa 57783 R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 57783 R-SSC-211873 https://reactome.org/PathwayBrowser/#/R-SSC-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Sus scrofa 57783 R-SSC-211923 https://reactome.org/PathwayBrowser/#/R-SSC-211923 CYP26C1 4-hydroxylates 9cRA IEA Sus scrofa 57783 R-SSC-211950 https://reactome.org/PathwayBrowser/#/R-SSC-211950 CYP24A1 24-hydroxylates CTL IEA Sus scrofa 57783 R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 57783 R-SSC-2161549 https://reactome.org/PathwayBrowser/#/R-SSC-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Sus scrofa 57783 R-SSC-2161614 https://reactome.org/PathwayBrowser/#/R-SSC-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Sus scrofa 57783 R-SSC-2161617 https://reactome.org/PathwayBrowser/#/R-SSC-2161617 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 TAS Sus scrofa 57783 R-SSC-2161651 https://reactome.org/PathwayBrowser/#/R-SSC-2161651 PGE2 is converted to PGF2a by CBR1 IEA Sus scrofa 57783 R-SSC-2161745 https://reactome.org/PathwayBrowser/#/R-SSC-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Sus scrofa 57783 R-SSC-2161792 https://reactome.org/PathwayBrowser/#/R-SSC-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Sus scrofa 57783 R-SSC-2161847 https://reactome.org/PathwayBrowser/#/R-SSC-2161847 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 TAS Sus scrofa 57783 R-SSC-2161890 https://reactome.org/PathwayBrowser/#/R-SSC-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Sus scrofa 57783 R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Sus scrofa 57783 R-SSC-2161951 https://reactome.org/PathwayBrowser/#/R-SSC-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Sus scrofa 57783 R-SSC-2395517 https://reactome.org/PathwayBrowser/#/R-SSC-2395517 NADPH transfers electrons to FDXR IEA Sus scrofa 57783 R-SSC-2464822 https://reactome.org/PathwayBrowser/#/R-SSC-2464822 RDH12 reduces atRAL to atROL IEA Sus scrofa 57783 R-SSC-2465940 https://reactome.org/PathwayBrowser/#/R-SSC-2465940 atRAL is reduced to atROL IEA Sus scrofa 57783 R-SSC-2855252 https://reactome.org/PathwayBrowser/#/R-SSC-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Sus scrofa 57783 R-SSC-3149518 https://reactome.org/PathwayBrowser/#/R-SSC-3149518 MTRR reduces cob(II)alamin to meCbl IEA Sus scrofa 57783 R-SSC-3149519 https://reactome.org/PathwayBrowser/#/R-SSC-3149519 MMACHC decyanates CNCbl IEA Sus scrofa 57783 R-SSC-3323079 https://reactome.org/PathwayBrowser/#/R-SSC-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 57783 R-SSC-350869 https://reactome.org/PathwayBrowser/#/R-SSC-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Sus scrofa 57783 R-SSC-389540 https://reactome.org/PathwayBrowser/#/R-SSC-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 57783 R-SSC-390425 https://reactome.org/PathwayBrowser/#/R-SSC-390425 FAR1 reduces PalmCoA to HXOL IEA Sus scrofa 57783 R-SSC-390438 https://reactome.org/PathwayBrowser/#/R-SSC-390438 FAR2 reduces PalmCoA to HXOL IEA Sus scrofa 57783 R-SSC-418436 https://reactome.org/PathwayBrowser/#/R-SSC-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Sus scrofa 57783 R-SSC-428123 https://reactome.org/PathwayBrowser/#/R-SSC-428123 KDSR reduces 3-ketosphingoid IEA Sus scrofa 57783 R-SSC-4419979 https://reactome.org/PathwayBrowser/#/R-SSC-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Sus scrofa 57783 R-SSC-450984 https://reactome.org/PathwayBrowser/#/R-SSC-450984 IDH2 dimer decarboxylates isocitrate IEA Sus scrofa 57783 R-SSC-469659 https://reactome.org/PathwayBrowser/#/R-SSC-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Sus scrofa 57783 R-SSC-508040 https://reactome.org/PathwayBrowser/#/R-SSC-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Sus scrofa 57783 R-SSC-514604 https://reactome.org/PathwayBrowser/#/R-SSC-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Sus scrofa 57783 R-SSC-5218841 https://reactome.org/PathwayBrowser/#/R-SSC-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Sus scrofa 57783 R-SSC-5340226 https://reactome.org/PathwayBrowser/#/R-SSC-5340226 CYGB dioxygenates NO IEA Sus scrofa 57783 R-SSC-5362525 https://reactome.org/PathwayBrowser/#/R-SSC-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Sus scrofa 57783 R-SSC-5419165 https://reactome.org/PathwayBrowser/#/R-SSC-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Sus scrofa 57783 R-SSC-5423637 https://reactome.org/PathwayBrowser/#/R-SSC-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Sus scrofa 57783 R-SSC-5423647 https://reactome.org/PathwayBrowser/#/R-SSC-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Sus scrofa 57783 R-SSC-5423664 https://reactome.org/PathwayBrowser/#/R-SSC-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Sus scrofa 57783 R-SSC-5423672 https://reactome.org/PathwayBrowser/#/R-SSC-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Sus scrofa 57783 R-SSC-5423678 https://reactome.org/PathwayBrowser/#/R-SSC-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Sus scrofa 57783 R-SSC-548818 https://reactome.org/PathwayBrowser/#/R-SSC-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Sus scrofa 57783 R-SSC-548831 https://reactome.org/PathwayBrowser/#/R-SSC-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Sus scrofa 57783 R-SSC-5602295 https://reactome.org/PathwayBrowser/#/R-SSC-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Sus scrofa 57783 R-SSC-5615668 https://reactome.org/PathwayBrowser/#/R-SSC-5615668 AKR1C3 reduces atRAL to atROL IEA Sus scrofa 57783 R-SSC-5652172 https://reactome.org/PathwayBrowser/#/R-SSC-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Sus scrofa 57783 R-SSC-5661240 https://reactome.org/PathwayBrowser/#/R-SSC-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Sus scrofa 57783 R-SSC-5661256 https://reactome.org/PathwayBrowser/#/R-SSC-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Sus scrofa 57783 R-SSC-5668629 https://reactome.org/PathwayBrowser/#/R-SSC-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Sus scrofa 57783 R-SSC-5668718 https://reactome.org/PathwayBrowser/#/R-SSC-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 57783 R-SSC-5668731 https://reactome.org/PathwayBrowser/#/R-SSC-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 57783 R-SSC-5692232 https://reactome.org/PathwayBrowser/#/R-SSC-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Sus scrofa 57783 R-SSC-5692283 https://reactome.org/PathwayBrowser/#/R-SSC-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Sus scrofa 57783 R-SSC-5693390 https://reactome.org/PathwayBrowser/#/R-SSC-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Sus scrofa 57783 R-SSC-6783955 https://reactome.org/PathwayBrowser/#/R-SSC-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 57783 R-SSC-6786239 https://reactome.org/PathwayBrowser/#/R-SSC-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Sus scrofa 57783 R-SSC-6787642 https://reactome.org/PathwayBrowser/#/R-SSC-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Sus scrofa 57783 R-SSC-6789092 https://reactome.org/PathwayBrowser/#/R-SSC-6789092 NOX2 generates superoxide anion from oxygen IEA Sus scrofa 57783 R-SSC-6799722 https://reactome.org/PathwayBrowser/#/R-SSC-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Sus scrofa 57783 R-SSC-6806967 https://reactome.org/PathwayBrowser/#/R-SSC-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Sus scrofa 57783 R-SSC-6807053 https://reactome.org/PathwayBrowser/#/R-SSC-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Sus scrofa 57783 R-SSC-6807055 https://reactome.org/PathwayBrowser/#/R-SSC-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Sus scrofa 57783 R-SSC-6807064 https://reactome.org/PathwayBrowser/#/R-SSC-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Sus scrofa 57783 R-SSC-6807557 https://reactome.org/PathwayBrowser/#/R-SSC-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Sus scrofa 57783 R-SSC-6808487 https://reactome.org/PathwayBrowser/#/R-SSC-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 57783 R-SSC-6808496 https://reactome.org/PathwayBrowser/#/R-SSC-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 57783 R-SSC-70377 https://reactome.org/PathwayBrowser/#/R-SSC-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Sus scrofa 57783 R-SSC-70577 https://reactome.org/PathwayBrowser/#/R-SSC-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Sus scrofa 57783 R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Sus scrofa 57783 R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Sus scrofa 57783 R-SSC-70938 https://reactome.org/PathwayBrowser/#/R-SSC-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Sus scrofa 57783 R-SSC-71200 https://reactome.org/PathwayBrowser/#/R-SSC-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Sus scrofa 57783 R-SSC-71299 https://reactome.org/PathwayBrowser/#/R-SSC-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Sus scrofa 57783 R-SSC-71682 https://reactome.org/PathwayBrowser/#/R-SSC-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 57783 R-SSC-73585 https://reactome.org/PathwayBrowser/#/R-SSC-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Sus scrofa 57783 R-SSC-73616 https://reactome.org/PathwayBrowser/#/R-SSC-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Sus scrofa 57783 R-SSC-74872 https://reactome.org/PathwayBrowser/#/R-SSC-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Sus scrofa 57783 R-SSC-75872 https://reactome.org/PathwayBrowser/#/R-SSC-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Sus scrofa 57783 R-SSC-75883 https://reactome.org/PathwayBrowser/#/R-SSC-75883 DHRS7B reduces GO3P to HXDG3P IEA Sus scrofa 57783 R-SSC-804969 https://reactome.org/PathwayBrowser/#/R-SSC-804969 HSD17B1 hydrogenates E1 to EST17b IEA Sus scrofa 57783 R-SSC-8862137 https://reactome.org/PathwayBrowser/#/R-SSC-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Sus scrofa 57783 R-SSC-8862152 https://reactome.org/PathwayBrowser/#/R-SSC-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Sus scrofa 57783 R-SSC-8865107 https://reactome.org/PathwayBrowser/#/R-SSC-8865107 MICAL1 produces NADP+, H2O2 IEA Sus scrofa 57783 R-SSC-8937419 https://reactome.org/PathwayBrowser/#/R-SSC-8937419 CBR3 reduces DOX to DOXOL IEA Sus scrofa 57783 R-SSC-8952873 https://reactome.org/PathwayBrowser/#/R-SSC-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Sus scrofa 57783 R-SSC-9012036 https://reactome.org/PathwayBrowser/#/R-SSC-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Sus scrofa 57783 R-SSC-9012349 https://reactome.org/PathwayBrowser/#/R-SSC-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Sus scrofa 57783 R-SSC-9020255 https://reactome.org/PathwayBrowser/#/R-SSC-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Sus scrofa 57783 R-SSC-9020256 https://reactome.org/PathwayBrowser/#/R-SSC-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Sus scrofa 57783 R-SSC-9020262 https://reactome.org/PathwayBrowser/#/R-SSC-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Sus scrofa 57783 R-SSC-9020277 https://reactome.org/PathwayBrowser/#/R-SSC-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Sus scrofa 57783 R-SSC-9020278 https://reactome.org/PathwayBrowser/#/R-SSC-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Sus scrofa 57783 R-SSC-9024881 https://reactome.org/PathwayBrowser/#/R-SSC-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Sus scrofa 57783 R-SSC-9024983 https://reactome.org/PathwayBrowser/#/R-SSC-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Sus scrofa 57783 R-SSC-9025995 https://reactome.org/PathwayBrowser/#/R-SSC-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Sus scrofa 57783 R-SSC-9025999 https://reactome.org/PathwayBrowser/#/R-SSC-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Sus scrofa 57783 R-SSC-9026007 https://reactome.org/PathwayBrowser/#/R-SSC-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Sus scrofa 57783 R-SSC-9027043 https://reactome.org/PathwayBrowser/#/R-SSC-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Sus scrofa 57783 R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 57783 R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 57783 R-SSC-9037761 https://reactome.org/PathwayBrowser/#/R-SSC-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Sus scrofa 57783 R-SSC-917811 https://reactome.org/PathwayBrowser/#/R-SSC-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Sus scrofa 57783 R-SSC-9705713 https://reactome.org/PathwayBrowser/#/R-SSC-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Sus scrofa 57783 R-SSC-9705714 https://reactome.org/PathwayBrowser/#/R-SSC-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Sus scrofa 57783 R-SSC-9709098 https://reactome.org/PathwayBrowser/#/R-SSC-9709098 DHFR dimer reduces FOLA to DHF IEA Sus scrofa 57783 R-SSC-9753285 https://reactome.org/PathwayBrowser/#/R-SSC-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Sus scrofa 57783 R-SSC-9755937 https://reactome.org/PathwayBrowser/#/R-SSC-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Sus scrofa 57783 R-SSC-9756138 https://reactome.org/PathwayBrowser/#/R-SSC-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Sus scrofa 57783 R-SSC-9756162 https://reactome.org/PathwayBrowser/#/R-SSC-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Sus scrofa 57783 R-SSC-9756169 https://reactome.org/PathwayBrowser/#/R-SSC-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Sus scrofa 57783 R-SSC-9756180 https://reactome.org/PathwayBrowser/#/R-SSC-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Sus scrofa 57783 R-SSC-975629 https://reactome.org/PathwayBrowser/#/R-SSC-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Sus scrofa 57783 R-SSC-9757706 https://reactome.org/PathwayBrowser/#/R-SSC-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Sus scrofa 57783 R-SSC-9758682 https://reactome.org/PathwayBrowser/#/R-SSC-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Sus scrofa 57783 R-SSC-9759259 https://reactome.org/PathwayBrowser/#/R-SSC-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Sus scrofa 57783 R-XTR-1222376 https://reactome.org/PathwayBrowser/#/R-XTR-1222376 NOX2 generates superoxide from oxygen IEA Xenopus tropicalis 57783 R-XTR-1475414 https://reactome.org/PathwayBrowser/#/R-XTR-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Xenopus tropicalis 57783 R-XTR-1497869 https://reactome.org/PathwayBrowser/#/R-XTR-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Xenopus tropicalis 57783 R-XTR-156526 https://reactome.org/PathwayBrowser/#/R-XTR-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 57783 R-XTR-1655453 https://reactome.org/PathwayBrowser/#/R-XTR-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Xenopus tropicalis 57783 R-XTR-189384 https://reactome.org/PathwayBrowser/#/R-XTR-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Xenopus tropicalis 57783 R-XTR-189398 https://reactome.org/PathwayBrowser/#/R-XTR-189398 HMOX1 dimer, HMOX2 cleave heme IEA Xenopus tropicalis 57783 R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 57783 R-XTR-191352 https://reactome.org/PathwayBrowser/#/R-XTR-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Xenopus tropicalis 57783 R-XTR-191402 https://reactome.org/PathwayBrowser/#/R-XTR-191402 Reduction of presqualene diphosphate to form squalene IEA Xenopus tropicalis 57783 R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 57783 R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 57783 R-XTR-192033 https://reactome.org/PathwayBrowser/#/R-XTR-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Xenopus tropicalis 57783 R-XTR-192036 https://reactome.org/PathwayBrowser/#/R-XTR-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Xenopus tropicalis 57783 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 57783 R-XTR-192061 https://reactome.org/PathwayBrowser/#/R-XTR-192061 CYP46A1 24-hydroxylates CHOL IEA Xenopus tropicalis 57783 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 57783 R-XTR-192067 https://reactome.org/PathwayBrowser/#/R-XTR-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Xenopus tropicalis 57783 R-XTR-192157 https://reactome.org/PathwayBrowser/#/R-XTR-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Xenopus tropicalis 57783 R-XTR-192160 https://reactome.org/PathwayBrowser/#/R-XTR-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Xenopus tropicalis 57783 R-XTR-192178 https://reactome.org/PathwayBrowser/#/R-XTR-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Xenopus tropicalis 57783 R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 57783 R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 57783 R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 57783 R-XTR-193068 https://reactome.org/PathwayBrowser/#/R-XTR-193068 CYP17A1 17-hydroxylates PREG IEA Xenopus tropicalis 57783 R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 57783 R-XTR-193072 https://reactome.org/PathwayBrowser/#/R-XTR-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Xenopus tropicalis 57783 R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 57783 R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 57783 R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 57783 R-XTR-193709 https://reactome.org/PathwayBrowser/#/R-XTR-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Xenopus tropicalis 57783 R-XTR-193746 https://reactome.org/PathwayBrowser/#/R-XTR-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 57783 R-XTR-193755 https://reactome.org/PathwayBrowser/#/R-XTR-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Xenopus tropicalis 57783 R-XTR-193758 https://reactome.org/PathwayBrowser/#/R-XTR-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Xenopus tropicalis 57783 R-XTR-193781 https://reactome.org/PathwayBrowser/#/R-XTR-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Xenopus tropicalis 57783 R-XTR-193800 https://reactome.org/PathwayBrowser/#/R-XTR-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Xenopus tropicalis 57783 R-XTR-193821 https://reactome.org/PathwayBrowser/#/R-XTR-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Xenopus tropicalis 57783 R-XTR-193824 https://reactome.org/PathwayBrowser/#/R-XTR-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Xenopus tropicalis 57783 R-XTR-193841 https://reactome.org/PathwayBrowser/#/R-XTR-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Xenopus tropicalis 57783 R-XTR-193845 https://reactome.org/PathwayBrowser/#/R-XTR-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Xenopus tropicalis 57783 R-XTR-193965 https://reactome.org/PathwayBrowser/#/R-XTR-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Xenopus tropicalis 57783 R-XTR-193995 https://reactome.org/PathwayBrowser/#/R-XTR-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Xenopus tropicalis 57783 R-XTR-193997 https://reactome.org/PathwayBrowser/#/R-XTR-193997 CYP11B1 oxidises 11DCORT IEA Xenopus tropicalis 57783 R-XTR-194017 https://reactome.org/PathwayBrowser/#/R-XTR-194017 CYP11B2 oxidises 11DCORST to CORST IEA Xenopus tropicalis 57783 R-XTR-194023 https://reactome.org/PathwayBrowser/#/R-XTR-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Xenopus tropicalis 57783 R-XTR-194641 https://reactome.org/PathwayBrowser/#/R-XTR-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 57783 R-XTR-194669 https://reactome.org/PathwayBrowser/#/R-XTR-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 57783 R-XTR-195664 https://reactome.org/PathwayBrowser/#/R-XTR-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Xenopus tropicalis 57783 R-XTR-196060 https://reactome.org/PathwayBrowser/#/R-XTR-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Xenopus tropicalis 57783 R-XTR-196402 https://reactome.org/PathwayBrowser/#/R-XTR-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Xenopus tropicalis 57783 R-XTR-196417 https://reactome.org/PathwayBrowser/#/R-XTR-196417 Reduction of desmosterol to cholesterol IEA Xenopus tropicalis 57783 R-XTR-200644 https://reactome.org/PathwayBrowser/#/R-XTR-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Xenopus tropicalis 57783 R-XTR-200676 https://reactome.org/PathwayBrowser/#/R-XTR-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Xenopus tropicalis 57783 R-XTR-200718 https://reactome.org/PathwayBrowser/#/R-XTR-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Xenopus tropicalis 57783 R-XTR-209845 https://reactome.org/PathwayBrowser/#/R-XTR-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Xenopus tropicalis 57783 R-XTR-211873 https://reactome.org/PathwayBrowser/#/R-XTR-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Xenopus tropicalis 57783 R-XTR-211923 https://reactome.org/PathwayBrowser/#/R-XTR-211923 CYP26C1 4-hydroxylates 9cRA IEA Xenopus tropicalis 57783 R-XTR-2161549 https://reactome.org/PathwayBrowser/#/R-XTR-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Xenopus tropicalis 57783 R-XTR-2161614 https://reactome.org/PathwayBrowser/#/R-XTR-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Xenopus tropicalis 57783 R-XTR-2161651 https://reactome.org/PathwayBrowser/#/R-XTR-2161651 PGE2 is converted to PGF2a by CBR1 IEA Xenopus tropicalis 57783 R-XTR-2161745 https://reactome.org/PathwayBrowser/#/R-XTR-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 57783 R-XTR-2161792 https://reactome.org/PathwayBrowser/#/R-XTR-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 57783 R-XTR-2161890 https://reactome.org/PathwayBrowser/#/R-XTR-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Xenopus tropicalis 57783 R-XTR-2161899 https://reactome.org/PathwayBrowser/#/R-XTR-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Xenopus tropicalis 57783 R-XTR-2161951 https://reactome.org/PathwayBrowser/#/R-XTR-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Xenopus tropicalis 57783 R-XTR-2395517 https://reactome.org/PathwayBrowser/#/R-XTR-2395517 NADPH transfers electrons to FDXR IEA Xenopus tropicalis 57783 R-XTR-2465940 https://reactome.org/PathwayBrowser/#/R-XTR-2465940 atRAL is reduced to atROL IEA Xenopus tropicalis 57783 R-XTR-2855252 https://reactome.org/PathwayBrowser/#/R-XTR-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Xenopus tropicalis 57783 R-XTR-3149519 https://reactome.org/PathwayBrowser/#/R-XTR-3149519 MMACHC decyanates CNCbl IEA Xenopus tropicalis 57783 R-XTR-3323079 https://reactome.org/PathwayBrowser/#/R-XTR-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 57783 R-XTR-389540 https://reactome.org/PathwayBrowser/#/R-XTR-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 57783 R-XTR-428123 https://reactome.org/PathwayBrowser/#/R-XTR-428123 KDSR reduces 3-ketosphingoid IEA Xenopus tropicalis 57783 R-XTR-4419979 https://reactome.org/PathwayBrowser/#/R-XTR-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Xenopus tropicalis 57783 R-XTR-450971 https://reactome.org/PathwayBrowser/#/R-XTR-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Xenopus tropicalis 57783 R-XTR-450984 https://reactome.org/PathwayBrowser/#/R-XTR-450984 IDH2 dimer decarboxylates isocitrate IEA Xenopus tropicalis 57783 R-XTR-469659 https://reactome.org/PathwayBrowser/#/R-XTR-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 57783 R-XTR-508040 https://reactome.org/PathwayBrowser/#/R-XTR-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Xenopus tropicalis 57783 R-XTR-514604 https://reactome.org/PathwayBrowser/#/R-XTR-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Xenopus tropicalis 57783 R-XTR-5218841 https://reactome.org/PathwayBrowser/#/R-XTR-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Xenopus tropicalis 57783 R-XTR-5340226 https://reactome.org/PathwayBrowser/#/R-XTR-5340226 CYGB dioxygenates NO IEA Xenopus tropicalis 57783 R-XTR-5362525 https://reactome.org/PathwayBrowser/#/R-XTR-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Xenopus tropicalis 57783 R-XTR-5419165 https://reactome.org/PathwayBrowser/#/R-XTR-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Xenopus tropicalis 57783 R-XTR-5423647 https://reactome.org/PathwayBrowser/#/R-XTR-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Xenopus tropicalis 57783 R-XTR-5423664 https://reactome.org/PathwayBrowser/#/R-XTR-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Xenopus tropicalis 57783 R-XTR-5423672 https://reactome.org/PathwayBrowser/#/R-XTR-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Xenopus tropicalis 57783 R-XTR-548818 https://reactome.org/PathwayBrowser/#/R-XTR-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Xenopus tropicalis 57783 R-XTR-548831 https://reactome.org/PathwayBrowser/#/R-XTR-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Xenopus tropicalis 57783 R-XTR-5602295 https://reactome.org/PathwayBrowser/#/R-XTR-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Xenopus tropicalis 57783 R-XTR-5615668 https://reactome.org/PathwayBrowser/#/R-XTR-5615668 AKR1C3 reduces atRAL to atROL IEA Xenopus tropicalis 57783 R-XTR-5652172 https://reactome.org/PathwayBrowser/#/R-XTR-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Xenopus tropicalis 57783 R-XTR-5661240 https://reactome.org/PathwayBrowser/#/R-XTR-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Xenopus tropicalis 57783 R-XTR-5661256 https://reactome.org/PathwayBrowser/#/R-XTR-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Xenopus tropicalis 57783 R-XTR-5668629 https://reactome.org/PathwayBrowser/#/R-XTR-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Xenopus tropicalis 57783 R-XTR-5668718 https://reactome.org/PathwayBrowser/#/R-XTR-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 57783 R-XTR-5668731 https://reactome.org/PathwayBrowser/#/R-XTR-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 57783 R-XTR-5692232 https://reactome.org/PathwayBrowser/#/R-XTR-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Xenopus tropicalis 57783 R-XTR-5693390 https://reactome.org/PathwayBrowser/#/R-XTR-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Xenopus tropicalis 57783 R-XTR-5696822 https://reactome.org/PathwayBrowser/#/R-XTR-5696822 AKR1B15 reduces EST17b to E1 IEA Xenopus tropicalis 57783 R-XTR-6786239 https://reactome.org/PathwayBrowser/#/R-XTR-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Xenopus tropicalis 57783 R-XTR-6787642 https://reactome.org/PathwayBrowser/#/R-XTR-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Xenopus tropicalis 57783 R-XTR-6789092 https://reactome.org/PathwayBrowser/#/R-XTR-6789092 NOX2 generates superoxide anion from oxygen IEA Xenopus tropicalis 57783 R-XTR-6799722 https://reactome.org/PathwayBrowser/#/R-XTR-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Xenopus tropicalis 57783 R-XTR-6806967 https://reactome.org/PathwayBrowser/#/R-XTR-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Xenopus tropicalis 57783 R-XTR-6807053 https://reactome.org/PathwayBrowser/#/R-XTR-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Xenopus tropicalis 57783 R-XTR-6807055 https://reactome.org/PathwayBrowser/#/R-XTR-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Xenopus tropicalis 57783 R-XTR-6807064 https://reactome.org/PathwayBrowser/#/R-XTR-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Xenopus tropicalis 57783 R-XTR-6808487 https://reactome.org/PathwayBrowser/#/R-XTR-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 57783 R-XTR-6808496 https://reactome.org/PathwayBrowser/#/R-XTR-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 57783 R-XTR-6810594 https://reactome.org/PathwayBrowser/#/R-XTR-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 57783 R-XTR-70377 https://reactome.org/PathwayBrowser/#/R-XTR-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Xenopus tropicalis 57783 R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Xenopus tropicalis 57783 R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Xenopus tropicalis 57783 R-XTR-70938 https://reactome.org/PathwayBrowser/#/R-XTR-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Xenopus tropicalis 57783 R-XTR-71200 https://reactome.org/PathwayBrowser/#/R-XTR-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Xenopus tropicalis 57783 R-XTR-71682 https://reactome.org/PathwayBrowser/#/R-XTR-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 57783 R-XTR-73585 https://reactome.org/PathwayBrowser/#/R-XTR-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Xenopus tropicalis 57783 R-XTR-73616 https://reactome.org/PathwayBrowser/#/R-XTR-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Xenopus tropicalis 57783 R-XTR-74872 https://reactome.org/PathwayBrowser/#/R-XTR-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 57783 R-XTR-75872 https://reactome.org/PathwayBrowser/#/R-XTR-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Xenopus tropicalis 57783 R-XTR-75883 https://reactome.org/PathwayBrowser/#/R-XTR-75883 DHRS7B reduces GO3P to HXDG3P IEA Xenopus tropicalis 57783 R-XTR-804969 https://reactome.org/PathwayBrowser/#/R-XTR-804969 HSD17B1 hydrogenates E1 to EST17b IEA Xenopus tropicalis 57783 R-XTR-8862137 https://reactome.org/PathwayBrowser/#/R-XTR-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 57783 R-XTR-8862152 https://reactome.org/PathwayBrowser/#/R-XTR-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Xenopus tropicalis 57783 R-XTR-8865107 https://reactome.org/PathwayBrowser/#/R-XTR-8865107 MICAL1 produces NADP+, H2O2 IEA Xenopus tropicalis 57783 R-XTR-8937419 https://reactome.org/PathwayBrowser/#/R-XTR-8937419 CBR3 reduces DOX to DOXOL IEA Xenopus tropicalis 57783 R-XTR-8952873 https://reactome.org/PathwayBrowser/#/R-XTR-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Xenopus tropicalis 57783 R-XTR-9012349 https://reactome.org/PathwayBrowser/#/R-XTR-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 57783 R-XTR-9020255 https://reactome.org/PathwayBrowser/#/R-XTR-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Xenopus tropicalis 57783 R-XTR-9020256 https://reactome.org/PathwayBrowser/#/R-XTR-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Xenopus tropicalis 57783 R-XTR-9020277 https://reactome.org/PathwayBrowser/#/R-XTR-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Xenopus tropicalis 57783 R-XTR-9020278 https://reactome.org/PathwayBrowser/#/R-XTR-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Xenopus tropicalis 57783 R-XTR-9025995 https://reactome.org/PathwayBrowser/#/R-XTR-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Xenopus tropicalis 57783 R-XTR-9025999 https://reactome.org/PathwayBrowser/#/R-XTR-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Xenopus tropicalis 57783 R-XTR-9027043 https://reactome.org/PathwayBrowser/#/R-XTR-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Xenopus tropicalis 57783 R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 57783 R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 57783 R-XTR-917811 https://reactome.org/PathwayBrowser/#/R-XTR-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Xenopus tropicalis 57783 R-XTR-9705713 https://reactome.org/PathwayBrowser/#/R-XTR-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 57783 R-XTR-9705714 https://reactome.org/PathwayBrowser/#/R-XTR-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 57783 R-XTR-9753285 https://reactome.org/PathwayBrowser/#/R-XTR-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Xenopus tropicalis 57783 R-XTR-9755937 https://reactome.org/PathwayBrowser/#/R-XTR-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Xenopus tropicalis 57783 R-XTR-9756138 https://reactome.org/PathwayBrowser/#/R-XTR-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Xenopus tropicalis 57783 R-XTR-9756162 https://reactome.org/PathwayBrowser/#/R-XTR-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Xenopus tropicalis 57783 R-XTR-9756169 https://reactome.org/PathwayBrowser/#/R-XTR-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Xenopus tropicalis 57783 R-XTR-9756180 https://reactome.org/PathwayBrowser/#/R-XTR-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Xenopus tropicalis 57783 R-XTR-9757706 https://reactome.org/PathwayBrowser/#/R-XTR-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Xenopus tropicalis 57783 R-XTR-9758682 https://reactome.org/PathwayBrowser/#/R-XTR-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Xenopus tropicalis 57783 R-XTR-9759259 https://reactome.org/PathwayBrowser/#/R-XTR-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Xenopus tropicalis 57795 R-BTA-1675776 https://reactome.org/PathwayBrowser/#/R-BTA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Bos taurus 57795 R-BTA-1675810 https://reactome.org/PathwayBrowser/#/R-BTA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Bos taurus 57795 R-BTA-1676065 https://reactome.org/PathwayBrowser/#/R-BTA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Bos taurus 57795 R-BTA-1676105 https://reactome.org/PathwayBrowser/#/R-BTA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Bos taurus 57795 R-BTA-1676203 https://reactome.org/PathwayBrowser/#/R-BTA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Bos taurus 57795 R-BTA-6809320 https://reactome.org/PathwayBrowser/#/R-BTA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Bos taurus 57795 R-BTA-6809778 https://reactome.org/PathwayBrowser/#/R-BTA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Bos taurus 57795 R-BTA-6810376 https://reactome.org/PathwayBrowser/#/R-BTA-6810376 ING2 binds PI5P IEA Bos taurus 57795 R-BTA-6810410 https://reactome.org/PathwayBrowser/#/R-BTA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Bos taurus 57795 R-BTA-6811508 https://reactome.org/PathwayBrowser/#/R-BTA-6811508 ING2-bound EP300 acetylates TP53 IEA Bos taurus 57795 R-BTA-6811522 https://reactome.org/PathwayBrowser/#/R-BTA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Bos taurus 57795 R-BTA-8849969 https://reactome.org/PathwayBrowser/#/R-BTA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Bos taurus 57795 R-BTA-8857925 https://reactome.org/PathwayBrowser/#/R-BTA-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Bos taurus 57795 R-CEL-1675776 https://reactome.org/PathwayBrowser/#/R-CEL-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Caenorhabditis elegans 57795 R-CEL-1675810 https://reactome.org/PathwayBrowser/#/R-CEL-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Caenorhabditis elegans 57795 R-CEL-1676065 https://reactome.org/PathwayBrowser/#/R-CEL-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Caenorhabditis elegans 57795 R-CEL-1676105 https://reactome.org/PathwayBrowser/#/R-CEL-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Caenorhabditis elegans 57795 R-CEL-1676203 https://reactome.org/PathwayBrowser/#/R-CEL-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Caenorhabditis elegans 57795 R-CEL-6809320 https://reactome.org/PathwayBrowser/#/R-CEL-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Caenorhabditis elegans 57795 R-CEL-6809778 https://reactome.org/PathwayBrowser/#/R-CEL-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Caenorhabditis elegans 57795 R-CEL-6810410 https://reactome.org/PathwayBrowser/#/R-CEL-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Caenorhabditis elegans 57795 R-CEL-6811504 https://reactome.org/PathwayBrowser/#/R-CEL-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Caenorhabditis elegans 57795 R-CEL-6811522 https://reactome.org/PathwayBrowser/#/R-CEL-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Caenorhabditis elegans 57795 R-CEL-8849969 https://reactome.org/PathwayBrowser/#/R-CEL-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Caenorhabditis elegans 57795 R-CEL-8857925 https://reactome.org/PathwayBrowser/#/R-CEL-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Caenorhabditis elegans 57795 R-CFA-1675776 https://reactome.org/PathwayBrowser/#/R-CFA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Canis familiaris 57795 R-CFA-1675810 https://reactome.org/PathwayBrowser/#/R-CFA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Canis familiaris 57795 R-CFA-1676065 https://reactome.org/PathwayBrowser/#/R-CFA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Canis familiaris 57795 R-CFA-1676105 https://reactome.org/PathwayBrowser/#/R-CFA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Canis familiaris 57795 R-CFA-1676203 https://reactome.org/PathwayBrowser/#/R-CFA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Canis familiaris 57795 R-CFA-6809320 https://reactome.org/PathwayBrowser/#/R-CFA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Canis familiaris 57795 R-CFA-6809778 https://reactome.org/PathwayBrowser/#/R-CFA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Canis familiaris 57795 R-CFA-6810376 https://reactome.org/PathwayBrowser/#/R-CFA-6810376 ING2 binds PI5P IEA Canis familiaris 57795 R-CFA-6810410 https://reactome.org/PathwayBrowser/#/R-CFA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Canis familiaris 57795 R-CFA-6811508 https://reactome.org/PathwayBrowser/#/R-CFA-6811508 ING2-bound EP300 acetylates TP53 IEA Canis familiaris 57795 R-CFA-6811522 https://reactome.org/PathwayBrowser/#/R-CFA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Canis familiaris 57795 R-CFA-8849969 https://reactome.org/PathwayBrowser/#/R-CFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Canis familiaris 57795 R-CFA-8857925 https://reactome.org/PathwayBrowser/#/R-CFA-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Canis familiaris 57795 R-DDI-1675776 https://reactome.org/PathwayBrowser/#/R-DDI-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Dictyostelium discoideum 57795 R-DDI-1675810 https://reactome.org/PathwayBrowser/#/R-DDI-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Dictyostelium discoideum 57795 R-DDI-1676065 https://reactome.org/PathwayBrowser/#/R-DDI-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Dictyostelium discoideum 57795 R-DDI-1676105 https://reactome.org/PathwayBrowser/#/R-DDI-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Dictyostelium discoideum 57795 R-DDI-1676203 https://reactome.org/PathwayBrowser/#/R-DDI-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Dictyostelium discoideum 57795 R-DDI-6809320 https://reactome.org/PathwayBrowser/#/R-DDI-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Dictyostelium discoideum 57795 R-DDI-6809778 https://reactome.org/PathwayBrowser/#/R-DDI-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Dictyostelium discoideum 57795 R-DDI-6811504 https://reactome.org/PathwayBrowser/#/R-DDI-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Dictyostelium discoideum 57795 R-DDI-6811522 https://reactome.org/PathwayBrowser/#/R-DDI-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Dictyostelium discoideum 57795 R-DDI-8849969 https://reactome.org/PathwayBrowser/#/R-DDI-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Dictyostelium discoideum 57795 R-DME-1675776 https://reactome.org/PathwayBrowser/#/R-DME-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Drosophila melanogaster 57795 R-DME-1675810 https://reactome.org/PathwayBrowser/#/R-DME-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Drosophila melanogaster 57795 R-DME-1676065 https://reactome.org/PathwayBrowser/#/R-DME-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Drosophila melanogaster 57795 R-DME-1676105 https://reactome.org/PathwayBrowser/#/R-DME-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Drosophila melanogaster 57795 R-DME-1676203 https://reactome.org/PathwayBrowser/#/R-DME-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Drosophila melanogaster 57795 R-DME-6809320 https://reactome.org/PathwayBrowser/#/R-DME-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Drosophila melanogaster 57795 R-DME-6809778 https://reactome.org/PathwayBrowser/#/R-DME-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Drosophila melanogaster 57795 R-DME-6810376 https://reactome.org/PathwayBrowser/#/R-DME-6810376 ING2 binds PI5P IEA Drosophila melanogaster 57795 R-DME-6810410 https://reactome.org/PathwayBrowser/#/R-DME-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Drosophila melanogaster 57795 R-DME-6811504 https://reactome.org/PathwayBrowser/#/R-DME-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Drosophila melanogaster 57795 R-DME-6811508 https://reactome.org/PathwayBrowser/#/R-DME-6811508 ING2-bound EP300 acetylates TP53 IEA Drosophila melanogaster 57795 R-DME-6811522 https://reactome.org/PathwayBrowser/#/R-DME-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Drosophila melanogaster 57795 R-DME-8849969 https://reactome.org/PathwayBrowser/#/R-DME-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Drosophila melanogaster 57795 R-DME-8857925 https://reactome.org/PathwayBrowser/#/R-DME-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Drosophila melanogaster 57795 R-DRE-1675776 https://reactome.org/PathwayBrowser/#/R-DRE-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Danio rerio 57795 R-DRE-1675810 https://reactome.org/PathwayBrowser/#/R-DRE-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Danio rerio 57795 R-DRE-1676065 https://reactome.org/PathwayBrowser/#/R-DRE-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Danio rerio 57795 R-DRE-1676105 https://reactome.org/PathwayBrowser/#/R-DRE-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Danio rerio 57795 R-DRE-1676203 https://reactome.org/PathwayBrowser/#/R-DRE-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Danio rerio 57795 R-DRE-6809320 https://reactome.org/PathwayBrowser/#/R-DRE-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Danio rerio 57795 R-DRE-6810376 https://reactome.org/PathwayBrowser/#/R-DRE-6810376 ING2 binds PI5P IEA Danio rerio 57795 R-DRE-6810410 https://reactome.org/PathwayBrowser/#/R-DRE-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Danio rerio 57795 R-DRE-6811504 https://reactome.org/PathwayBrowser/#/R-DRE-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Danio rerio 57795 R-DRE-6811522 https://reactome.org/PathwayBrowser/#/R-DRE-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Danio rerio 57795 R-DRE-8849969 https://reactome.org/PathwayBrowser/#/R-DRE-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Danio rerio 57795 R-GGA-1675776 https://reactome.org/PathwayBrowser/#/R-GGA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Gallus gallus 57795 R-GGA-1675810 https://reactome.org/PathwayBrowser/#/R-GGA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Gallus gallus 57795 R-GGA-1676065 https://reactome.org/PathwayBrowser/#/R-GGA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Gallus gallus 57795 R-GGA-1676105 https://reactome.org/PathwayBrowser/#/R-GGA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Gallus gallus 57795 R-GGA-1676203 https://reactome.org/PathwayBrowser/#/R-GGA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Gallus gallus 57795 R-GGA-6809320 https://reactome.org/PathwayBrowser/#/R-GGA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Gallus gallus 57795 R-GGA-6809778 https://reactome.org/PathwayBrowser/#/R-GGA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Gallus gallus 57795 R-GGA-6810376 https://reactome.org/PathwayBrowser/#/R-GGA-6810376 ING2 binds PI5P IEA Gallus gallus 57795 R-GGA-6811522 https://reactome.org/PathwayBrowser/#/R-GGA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Gallus gallus 57795 R-GGA-8849969 https://reactome.org/PathwayBrowser/#/R-GGA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Gallus gallus 57795 R-HSA-1675776 https://reactome.org/PathwayBrowser/#/R-HSA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane TAS Homo sapiens 57795 R-HSA-1675810 https://reactome.org/PathwayBrowser/#/R-HSA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane TAS Homo sapiens 57795 R-HSA-1675866 https://reactome.org/PathwayBrowser/#/R-HSA-1675866 PI is phosphorylated to PI5P by PIKFYVE at the late endosome membrane IEA Homo sapiens 57795 R-HSA-1676065 https://reactome.org/PathwayBrowser/#/R-HSA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane TAS Homo sapiens 57795 R-HSA-1676105 https://reactome.org/PathwayBrowser/#/R-HSA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane TAS Homo sapiens 57795 R-HSA-1676203 https://reactome.org/PathwayBrowser/#/R-HSA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane TAS Homo sapiens 57795 R-HSA-6809320 https://reactome.org/PathwayBrowser/#/R-HSA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane TAS Homo sapiens 57795 R-HSA-6809778 https://reactome.org/PathwayBrowser/#/R-HSA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 TAS Homo sapiens 57795 R-HSA-6809944 https://reactome.org/PathwayBrowser/#/R-HSA-6809944 PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane IEA Homo sapiens 57795 R-HSA-6810376 https://reactome.org/PathwayBrowser/#/R-HSA-6810376 ING2 binds PI5P TAS Homo sapiens 57795 R-HSA-6810410 https://reactome.org/PathwayBrowser/#/R-HSA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus TAS Homo sapiens 57795 R-HSA-6811504 https://reactome.org/PathwayBrowser/#/R-HSA-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma TAS Homo sapiens 57795 R-HSA-6811508 https://reactome.org/PathwayBrowser/#/R-HSA-6811508 ING2-bound EP300 acetylates TP53 TAS Homo sapiens 57795 R-HSA-6811522 https://reactome.org/PathwayBrowser/#/R-HSA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus TAS Homo sapiens 57795 R-HSA-8849969 https://reactome.org/PathwayBrowser/#/R-HSA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane TAS Homo sapiens 57795 R-HSA-8857925 https://reactome.org/PathwayBrowser/#/R-HSA-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 TAS Homo sapiens 57795 R-MMU-1675776 https://reactome.org/PathwayBrowser/#/R-MMU-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Mus musculus 57795 R-MMU-1675810 https://reactome.org/PathwayBrowser/#/R-MMU-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Mus musculus 57795 R-MMU-1676065 https://reactome.org/PathwayBrowser/#/R-MMU-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Mus musculus 57795 R-MMU-1676105 https://reactome.org/PathwayBrowser/#/R-MMU-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Mus musculus 57795 R-MMU-1676203 https://reactome.org/PathwayBrowser/#/R-MMU-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Mus musculus 57795 R-MMU-6809320 https://reactome.org/PathwayBrowser/#/R-MMU-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Mus musculus 57795 R-MMU-6809778 https://reactome.org/PathwayBrowser/#/R-MMU-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Mus musculus 57795 R-MMU-6809945 https://reactome.org/PathwayBrowser/#/R-MMU-6809945 PI(3,5)P2 is dephosphorylated to PI5P by the Mtmr2:Sbf2 tetramer at the plasma membrane TAS Mus musculus 57795 R-MMU-6810376 https://reactome.org/PathwayBrowser/#/R-MMU-6810376 ING2 binds PI5P IEA Mus musculus 57795 R-MMU-6810410 https://reactome.org/PathwayBrowser/#/R-MMU-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Mus musculus 57795 R-MMU-6811504 https://reactome.org/PathwayBrowser/#/R-MMU-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Mus musculus 57795 R-MMU-6811508 https://reactome.org/PathwayBrowser/#/R-MMU-6811508 ING2-bound EP300 acetylates TP53 IEA Mus musculus 57795 R-MMU-6811522 https://reactome.org/PathwayBrowser/#/R-MMU-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Mus musculus 57795 R-MMU-8849969 https://reactome.org/PathwayBrowser/#/R-MMU-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Mus musculus 57795 R-MMU-8857925 https://reactome.org/PathwayBrowser/#/R-MMU-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Mus musculus 57795 R-NUL-1676051 https://reactome.org/PathwayBrowser/#/R-NUL-1676051 PI is phosphorylated to PI5P by Pikfyve at the late endosome membrane TAS Mus musculus 57795 R-PFA-1675776 https://reactome.org/PathwayBrowser/#/R-PFA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Plasmodium falciparum 57795 R-PFA-1675810 https://reactome.org/PathwayBrowser/#/R-PFA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Plasmodium falciparum 57795 R-PFA-1676203 https://reactome.org/PathwayBrowser/#/R-PFA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Plasmodium falciparum 57795 R-PFA-6811522 https://reactome.org/PathwayBrowser/#/R-PFA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Plasmodium falciparum 57795 R-PFA-8849969 https://reactome.org/PathwayBrowser/#/R-PFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Plasmodium falciparum 57795 R-RNO-1675776 https://reactome.org/PathwayBrowser/#/R-RNO-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Rattus norvegicus 57795 R-RNO-1675810 https://reactome.org/PathwayBrowser/#/R-RNO-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Rattus norvegicus 57795 R-RNO-1676065 https://reactome.org/PathwayBrowser/#/R-RNO-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Rattus norvegicus 57795 R-RNO-1676105 https://reactome.org/PathwayBrowser/#/R-RNO-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Rattus norvegicus 57795 R-RNO-1676203 https://reactome.org/PathwayBrowser/#/R-RNO-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus 57795 R-RNO-6809320 https://reactome.org/PathwayBrowser/#/R-RNO-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Rattus norvegicus 57795 R-RNO-6809778 https://reactome.org/PathwayBrowser/#/R-RNO-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Rattus norvegicus 57795 R-RNO-6810376 https://reactome.org/PathwayBrowser/#/R-RNO-6810376 ING2 binds PI5P IEA Rattus norvegicus 57795 R-RNO-6810410 https://reactome.org/PathwayBrowser/#/R-RNO-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Rattus norvegicus 57795 R-RNO-6811504 https://reactome.org/PathwayBrowser/#/R-RNO-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Rattus norvegicus 57795 R-RNO-6811508 https://reactome.org/PathwayBrowser/#/R-RNO-6811508 ING2-bound EP300 acetylates TP53 IEA Rattus norvegicus 57795 R-RNO-6811522 https://reactome.org/PathwayBrowser/#/R-RNO-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Rattus norvegicus 57795 R-RNO-8849969 https://reactome.org/PathwayBrowser/#/R-RNO-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Rattus norvegicus 57795 R-RNO-8857925 https://reactome.org/PathwayBrowser/#/R-RNO-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Rattus norvegicus 57795 R-SCE-1675776 https://reactome.org/PathwayBrowser/#/R-SCE-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Saccharomyces cerevisiae 57795 R-SCE-1675810 https://reactome.org/PathwayBrowser/#/R-SCE-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Saccharomyces cerevisiae 57795 R-SCE-1676065 https://reactome.org/PathwayBrowser/#/R-SCE-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Saccharomyces cerevisiae 57795 R-SCE-1676105 https://reactome.org/PathwayBrowser/#/R-SCE-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Saccharomyces cerevisiae 57795 R-SCE-1676203 https://reactome.org/PathwayBrowser/#/R-SCE-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Saccharomyces cerevisiae 57795 R-SCE-6809320 https://reactome.org/PathwayBrowser/#/R-SCE-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Saccharomyces cerevisiae 57795 R-SCE-6809778 https://reactome.org/PathwayBrowser/#/R-SCE-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Saccharomyces cerevisiae 57795 R-SCE-6810376 https://reactome.org/PathwayBrowser/#/R-SCE-6810376 ING2 binds PI5P IEA Saccharomyces cerevisiae 57795 R-SCE-6811504 https://reactome.org/PathwayBrowser/#/R-SCE-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Saccharomyces cerevisiae 57795 R-SCE-6811522 https://reactome.org/PathwayBrowser/#/R-SCE-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Saccharomyces cerevisiae 57795 R-SPO-1675776 https://reactome.org/PathwayBrowser/#/R-SPO-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Schizosaccharomyces pombe 57795 R-SPO-1675810 https://reactome.org/PathwayBrowser/#/R-SPO-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Schizosaccharomyces pombe 57795 R-SPO-1676065 https://reactome.org/PathwayBrowser/#/R-SPO-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Schizosaccharomyces pombe 57795 R-SPO-1676105 https://reactome.org/PathwayBrowser/#/R-SPO-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Schizosaccharomyces pombe 57795 R-SPO-1676203 https://reactome.org/PathwayBrowser/#/R-SPO-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Schizosaccharomyces pombe 57795 R-SPO-6809320 https://reactome.org/PathwayBrowser/#/R-SPO-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Schizosaccharomyces pombe 57795 R-SPO-6809778 https://reactome.org/PathwayBrowser/#/R-SPO-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Schizosaccharomyces pombe 57795 R-SPO-6810376 https://reactome.org/PathwayBrowser/#/R-SPO-6810376 ING2 binds PI5P IEA Schizosaccharomyces pombe 57795 R-SPO-6811504 https://reactome.org/PathwayBrowser/#/R-SPO-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Schizosaccharomyces pombe 57795 R-SPO-6811522 https://reactome.org/PathwayBrowser/#/R-SPO-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Schizosaccharomyces pombe 57795 R-SSC-1675776 https://reactome.org/PathwayBrowser/#/R-SSC-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Sus scrofa 57795 R-SSC-1675810 https://reactome.org/PathwayBrowser/#/R-SSC-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Sus scrofa 57795 R-SSC-1676065 https://reactome.org/PathwayBrowser/#/R-SSC-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Sus scrofa 57795 R-SSC-1676105 https://reactome.org/PathwayBrowser/#/R-SSC-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Sus scrofa 57795 R-SSC-1676203 https://reactome.org/PathwayBrowser/#/R-SSC-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Sus scrofa 57795 R-SSC-6809320 https://reactome.org/PathwayBrowser/#/R-SSC-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Sus scrofa 57795 R-SSC-6809778 https://reactome.org/PathwayBrowser/#/R-SSC-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Sus scrofa 57795 R-SSC-6810376 https://reactome.org/PathwayBrowser/#/R-SSC-6810376 ING2 binds PI5P IEA Sus scrofa 57795 R-SSC-6810410 https://reactome.org/PathwayBrowser/#/R-SSC-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Sus scrofa 57795 R-SSC-6811508 https://reactome.org/PathwayBrowser/#/R-SSC-6811508 ING2-bound EP300 acetylates TP53 IEA Sus scrofa 57795 R-SSC-6811522 https://reactome.org/PathwayBrowser/#/R-SSC-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Sus scrofa 57795 R-SSC-8849969 https://reactome.org/PathwayBrowser/#/R-SSC-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Sus scrofa 57795 R-SSC-8857925 https://reactome.org/PathwayBrowser/#/R-SSC-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Sus scrofa 57795 R-XTR-1675776 https://reactome.org/PathwayBrowser/#/R-XTR-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Xenopus tropicalis 57795 R-XTR-1676065 https://reactome.org/PathwayBrowser/#/R-XTR-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Xenopus tropicalis 57795 R-XTR-1676105 https://reactome.org/PathwayBrowser/#/R-XTR-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Xenopus tropicalis 57795 R-XTR-1676203 https://reactome.org/PathwayBrowser/#/R-XTR-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Xenopus tropicalis 57795 R-XTR-6810376 https://reactome.org/PathwayBrowser/#/R-XTR-6810376 ING2 binds PI5P IEA Xenopus tropicalis 57795 R-XTR-6810410 https://reactome.org/PathwayBrowser/#/R-XTR-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Xenopus tropicalis 57795 R-XTR-6811508 https://reactome.org/PathwayBrowser/#/R-XTR-6811508 ING2-bound EP300 acetylates TP53 IEA Xenopus tropicalis 57795 R-XTR-6811522 https://reactome.org/PathwayBrowser/#/R-XTR-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Xenopus tropicalis 57795 R-XTR-8849969 https://reactome.org/PathwayBrowser/#/R-XTR-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Xenopus tropicalis 57812 R-BTA-2046285 https://reactome.org/PathwayBrowser/#/R-BTA-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Bos taurus 57812 R-BTA-4084978 https://reactome.org/PathwayBrowser/#/R-BTA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Bos taurus 57812 R-BTA-4084980 https://reactome.org/PathwayBrowser/#/R-BTA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Bos taurus 57812 R-BTA-4084982 https://reactome.org/PathwayBrowser/#/R-BTA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Bos taurus 57812 R-BTA-4084984 https://reactome.org/PathwayBrowser/#/R-BTA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Bos taurus 57812 R-BTA-4085033 https://reactome.org/PathwayBrowser/#/R-BTA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Bos taurus 57812 R-BTA-727807 https://reactome.org/PathwayBrowser/#/R-BTA-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Bos taurus 57812 R-BTA-9603987 https://reactome.org/PathwayBrowser/#/R-BTA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Bos taurus 57812 R-BTA-9603991 https://reactome.org/PathwayBrowser/#/R-BTA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Bos taurus 57812 R-BTA-9605600 https://reactome.org/PathwayBrowser/#/R-BTA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Bos taurus 57812 R-BTA-977071 https://reactome.org/PathwayBrowser/#/R-BTA-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Bos taurus 57812 R-BTA-981497 https://reactome.org/PathwayBrowser/#/R-BTA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Bos taurus 57812 R-BTA-981809 https://reactome.org/PathwayBrowser/#/R-BTA-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Bos taurus 57812 R-BTA-981814 https://reactome.org/PathwayBrowser/#/R-BTA-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Bos taurus 57812 R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 57812 R-BTA-9845538 https://reactome.org/PathwayBrowser/#/R-BTA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Bos taurus 57812 R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 57812 R-BTA-9846305 https://reactome.org/PathwayBrowser/#/R-BTA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Bos taurus 57812 R-CEL-727807 https://reactome.org/PathwayBrowser/#/R-CEL-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Caenorhabditis elegans 57812 R-CFA-2046285 https://reactome.org/PathwayBrowser/#/R-CFA-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Canis familiaris 57812 R-CFA-4084978 https://reactome.org/PathwayBrowser/#/R-CFA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Canis familiaris 57812 R-CFA-4084980 https://reactome.org/PathwayBrowser/#/R-CFA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Canis familiaris 57812 R-CFA-4084982 https://reactome.org/PathwayBrowser/#/R-CFA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Canis familiaris 57812 R-CFA-4084984 https://reactome.org/PathwayBrowser/#/R-CFA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Canis familiaris 57812 R-CFA-4085033 https://reactome.org/PathwayBrowser/#/R-CFA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Canis familiaris 57812 R-CFA-727807 https://reactome.org/PathwayBrowser/#/R-CFA-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Canis familiaris 57812 R-CFA-9603987 https://reactome.org/PathwayBrowser/#/R-CFA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Canis familiaris 57812 R-CFA-9603991 https://reactome.org/PathwayBrowser/#/R-CFA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Canis familiaris 57812 R-CFA-9605600 https://reactome.org/PathwayBrowser/#/R-CFA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Canis familiaris 57812 R-CFA-977071 https://reactome.org/PathwayBrowser/#/R-CFA-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Canis familiaris 57812 R-CFA-981497 https://reactome.org/PathwayBrowser/#/R-CFA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Canis familiaris 57812 R-CFA-981809 https://reactome.org/PathwayBrowser/#/R-CFA-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Canis familiaris 57812 R-CFA-981814 https://reactome.org/PathwayBrowser/#/R-CFA-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Canis familiaris 57812 R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 57812 R-CFA-9845538 https://reactome.org/PathwayBrowser/#/R-CFA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Canis familiaris 57812 R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 57812 R-CFA-9846305 https://reactome.org/PathwayBrowser/#/R-CFA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Canis familiaris 57812 R-CGR-2033005 https://reactome.org/PathwayBrowser/#/R-CGR-2033005 Sialylation of Pre-Notch TAS Cricetulus griseus 57812 R-DME-4085033 https://reactome.org/PathwayBrowser/#/R-DME-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Drosophila melanogaster 57812 R-DME-977071 https://reactome.org/PathwayBrowser/#/R-DME-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Drosophila melanogaster 57812 R-DRE-2046285 https://reactome.org/PathwayBrowser/#/R-DRE-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Danio rerio 57812 R-DRE-4084978 https://reactome.org/PathwayBrowser/#/R-DRE-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Danio rerio 57812 R-DRE-4084980 https://reactome.org/PathwayBrowser/#/R-DRE-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Danio rerio 57812 R-DRE-4084982 https://reactome.org/PathwayBrowser/#/R-DRE-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Danio rerio 57812 R-DRE-4084984 https://reactome.org/PathwayBrowser/#/R-DRE-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Danio rerio 57812 R-DRE-4085033 https://reactome.org/PathwayBrowser/#/R-DRE-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Danio rerio 57812 R-DRE-727807 https://reactome.org/PathwayBrowser/#/R-DRE-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Danio rerio 57812 R-DRE-9605600 https://reactome.org/PathwayBrowser/#/R-DRE-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Danio rerio 57812 R-DRE-981497 https://reactome.org/PathwayBrowser/#/R-DRE-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Danio rerio 57812 R-DRE-981809 https://reactome.org/PathwayBrowser/#/R-DRE-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Danio rerio 57812 R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 57812 R-GGA-2046285 https://reactome.org/PathwayBrowser/#/R-GGA-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Gallus gallus 57812 R-GGA-4084978 https://reactome.org/PathwayBrowser/#/R-GGA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Gallus gallus 57812 R-GGA-4084980 https://reactome.org/PathwayBrowser/#/R-GGA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Gallus gallus 57812 R-GGA-4084982 https://reactome.org/PathwayBrowser/#/R-GGA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Gallus gallus 57812 R-GGA-4084984 https://reactome.org/PathwayBrowser/#/R-GGA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Gallus gallus 57812 R-GGA-4085033 https://reactome.org/PathwayBrowser/#/R-GGA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Gallus gallus 57812 R-GGA-727807 https://reactome.org/PathwayBrowser/#/R-GGA-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Gallus gallus 57812 R-GGA-9603987 https://reactome.org/PathwayBrowser/#/R-GGA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Gallus gallus 57812 R-GGA-9603991 https://reactome.org/PathwayBrowser/#/R-GGA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Gallus gallus 57812 R-GGA-9605600 https://reactome.org/PathwayBrowser/#/R-GGA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Gallus gallus 57812 R-GGA-977071 https://reactome.org/PathwayBrowser/#/R-GGA-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Gallus gallus 57812 R-GGA-981497 https://reactome.org/PathwayBrowser/#/R-GGA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Gallus gallus 57812 R-GGA-981809 https://reactome.org/PathwayBrowser/#/R-GGA-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Gallus gallus 57812 R-GGA-981814 https://reactome.org/PathwayBrowser/#/R-GGA-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Gallus gallus 57812 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 57812 R-GGA-9845538 https://reactome.org/PathwayBrowser/#/R-GGA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Gallus gallus 57812 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 57812 R-GGA-9846305 https://reactome.org/PathwayBrowser/#/R-GGA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Gallus gallus 57812 R-HSA-1912378 https://reactome.org/PathwayBrowser/#/R-HSA-1912378 Sialylation of Pre-NOTCH IEA Homo sapiens 57812 R-HSA-2046285 https://reactome.org/PathwayBrowser/#/R-HSA-2046285 The keratan chain can be capped by N-acetylneuraminic acid TAS Homo sapiens 57812 R-HSA-3656258 https://reactome.org/PathwayBrowser/#/R-HSA-3656258 Defective ST3GAL3 does not transfer SA to keratan TAS Homo sapiens 57812 R-HSA-4084978 https://reactome.org/PathwayBrowser/#/R-HSA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues TAS Homo sapiens 57812 R-HSA-4084980 https://reactome.org/PathwayBrowser/#/R-HSA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) TAS Homo sapiens 57812 R-HSA-4084982 https://reactome.org/PathwayBrowser/#/R-HSA-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac TAS Homo sapiens 57812 R-HSA-4084984 https://reactome.org/PathwayBrowser/#/R-HSA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) TAS Homo sapiens 57812 R-HSA-4084990 https://reactome.org/PathwayBrowser/#/R-HSA-4084990 Nuclear CMP-Neu5Ac translocates to cytosol TAS Homo sapiens 57812 R-HSA-4085033 https://reactome.org/PathwayBrowser/#/R-HSA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) TAS Homo sapiens 57812 R-HSA-5651942 https://reactome.org/PathwayBrowser/#/R-HSA-5651942 Defective SLC35A1 does not exchange CMP-Neu5Ac for CMP TAS Homo sapiens 57812 R-HSA-727807 https://reactome.org/PathwayBrowser/#/R-HSA-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP TAS Homo sapiens 57812 R-HSA-9603987 https://reactome.org/PathwayBrowser/#/R-HSA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG TAS Homo sapiens 57812 R-HSA-9603991 https://reactome.org/PathwayBrowser/#/R-HSA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG TAS Homo sapiens 57812 R-HSA-9605600 https://reactome.org/PathwayBrowser/#/R-HSA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG TAS Homo sapiens 57812 R-HSA-9683769 https://reactome.org/PathwayBrowser/#/R-HSA-9683769 O-glycosylation of 3a is terminated TAS Homo sapiens 57812 R-HSA-9694718 https://reactome.org/PathwayBrowser/#/R-HSA-9694718 O-glycosylation of 3a is terminated IEA Homo sapiens 57812 R-HSA-977071 https://reactome.org/PathwayBrowser/#/R-HSA-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens TAS Homo sapiens 57812 R-HSA-981497 https://reactome.org/PathwayBrowser/#/R-HSA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position TAS Homo sapiens 57812 R-HSA-981809 https://reactome.org/PathwayBrowser/#/R-HSA-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen TAS Homo sapiens 57812 R-HSA-981814 https://reactome.org/PathwayBrowser/#/R-HSA-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins TAS Homo sapiens 57812 R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 57812 R-HSA-9845538 https://reactome.org/PathwayBrowser/#/R-HSA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides TAS Homo sapiens 57812 R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 57812 R-HSA-9846305 https://reactome.org/PathwayBrowser/#/R-HSA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b TAS Homo sapiens 57812 R-MMU-2046285 https://reactome.org/PathwayBrowser/#/R-MMU-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Mus musculus 57812 R-MMU-4084978 https://reactome.org/PathwayBrowser/#/R-MMU-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Mus musculus 57812 R-MMU-4084980 https://reactome.org/PathwayBrowser/#/R-MMU-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Mus musculus 57812 R-MMU-4084982 https://reactome.org/PathwayBrowser/#/R-MMU-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Mus musculus 57812 R-MMU-4084984 https://reactome.org/PathwayBrowser/#/R-MMU-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Mus musculus 57812 R-MMU-4085033 https://reactome.org/PathwayBrowser/#/R-MMU-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Mus musculus 57812 R-MMU-727807 https://reactome.org/PathwayBrowser/#/R-MMU-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Mus musculus 57812 R-MMU-9603987 https://reactome.org/PathwayBrowser/#/R-MMU-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Mus musculus 57812 R-MMU-9603991 https://reactome.org/PathwayBrowser/#/R-MMU-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Mus musculus 57812 R-MMU-9605600 https://reactome.org/PathwayBrowser/#/R-MMU-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Mus musculus 57812 R-MMU-977071 https://reactome.org/PathwayBrowser/#/R-MMU-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Mus musculus 57812 R-MMU-981497 https://reactome.org/PathwayBrowser/#/R-MMU-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Mus musculus 57812 R-MMU-981809 https://reactome.org/PathwayBrowser/#/R-MMU-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Mus musculus 57812 R-MMU-981814 https://reactome.org/PathwayBrowser/#/R-MMU-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Mus musculus 57812 R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 57812 R-MMU-9845538 https://reactome.org/PathwayBrowser/#/R-MMU-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Mus musculus 57812 R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 57812 R-MMU-9846305 https://reactome.org/PathwayBrowser/#/R-MMU-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Mus musculus 57812 R-PFA-727807 https://reactome.org/PathwayBrowser/#/R-PFA-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Plasmodium falciparum 57812 R-RNO-2046285 https://reactome.org/PathwayBrowser/#/R-RNO-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Rattus norvegicus 57812 R-RNO-4084978 https://reactome.org/PathwayBrowser/#/R-RNO-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Rattus norvegicus 57812 R-RNO-4084980 https://reactome.org/PathwayBrowser/#/R-RNO-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Rattus norvegicus 57812 R-RNO-4084982 https://reactome.org/PathwayBrowser/#/R-RNO-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Rattus norvegicus 57812 R-RNO-4084984 https://reactome.org/PathwayBrowser/#/R-RNO-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Rattus norvegicus 57812 R-RNO-4085033 https://reactome.org/PathwayBrowser/#/R-RNO-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Rattus norvegicus 57812 R-RNO-727807 https://reactome.org/PathwayBrowser/#/R-RNO-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Rattus norvegicus 57812 R-RNO-9603987 https://reactome.org/PathwayBrowser/#/R-RNO-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Rattus norvegicus 57812 R-RNO-9603991 https://reactome.org/PathwayBrowser/#/R-RNO-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Rattus norvegicus 57812 R-RNO-9605600 https://reactome.org/PathwayBrowser/#/R-RNO-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Rattus norvegicus 57812 R-RNO-977071 https://reactome.org/PathwayBrowser/#/R-RNO-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Rattus norvegicus 57812 R-RNO-981497 https://reactome.org/PathwayBrowser/#/R-RNO-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Rattus norvegicus 57812 R-RNO-981809 https://reactome.org/PathwayBrowser/#/R-RNO-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Rattus norvegicus 57812 R-RNO-981814 https://reactome.org/PathwayBrowser/#/R-RNO-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Rattus norvegicus 57812 R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 57812 R-RNO-9845538 https://reactome.org/PathwayBrowser/#/R-RNO-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Rattus norvegicus 57812 R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 57812 R-RNO-9846305 https://reactome.org/PathwayBrowser/#/R-RNO-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Rattus norvegicus 57812 R-SSC-2046285 https://reactome.org/PathwayBrowser/#/R-SSC-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Sus scrofa 57812 R-SSC-4084978 https://reactome.org/PathwayBrowser/#/R-SSC-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Sus scrofa 57812 R-SSC-4084980 https://reactome.org/PathwayBrowser/#/R-SSC-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Sus scrofa 57812 R-SSC-4084982 https://reactome.org/PathwayBrowser/#/R-SSC-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Sus scrofa 57812 R-SSC-4084984 https://reactome.org/PathwayBrowser/#/R-SSC-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Sus scrofa 57812 R-SSC-4085033 https://reactome.org/PathwayBrowser/#/R-SSC-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Sus scrofa 57812 R-SSC-727807 https://reactome.org/PathwayBrowser/#/R-SSC-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Sus scrofa 57812 R-SSC-9603987 https://reactome.org/PathwayBrowser/#/R-SSC-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Sus scrofa 57812 R-SSC-9603991 https://reactome.org/PathwayBrowser/#/R-SSC-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Sus scrofa 57812 R-SSC-9605600 https://reactome.org/PathwayBrowser/#/R-SSC-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Sus scrofa 57812 R-SSC-977071 https://reactome.org/PathwayBrowser/#/R-SSC-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Sus scrofa 57812 R-SSC-981497 https://reactome.org/PathwayBrowser/#/R-SSC-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Sus scrofa 57812 R-SSC-981809 https://reactome.org/PathwayBrowser/#/R-SSC-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Sus scrofa 57812 R-SSC-981814 https://reactome.org/PathwayBrowser/#/R-SSC-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Sus scrofa 57812 R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 57812 R-SSC-9845538 https://reactome.org/PathwayBrowser/#/R-SSC-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Sus scrofa 57812 R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 57812 R-SSC-9846305 https://reactome.org/PathwayBrowser/#/R-SSC-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Sus scrofa 57812 R-XTR-2046285 https://reactome.org/PathwayBrowser/#/R-XTR-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Xenopus tropicalis 57812 R-XTR-4084978 https://reactome.org/PathwayBrowser/#/R-XTR-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Xenopus tropicalis 57812 R-XTR-4084980 https://reactome.org/PathwayBrowser/#/R-XTR-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Xenopus tropicalis 57812 R-XTR-4084982 https://reactome.org/PathwayBrowser/#/R-XTR-4084982 CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac IEA Xenopus tropicalis 57812 R-XTR-4084984 https://reactome.org/PathwayBrowser/#/R-XTR-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Xenopus tropicalis 57812 R-XTR-4085033 https://reactome.org/PathwayBrowser/#/R-XTR-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Xenopus tropicalis 57812 R-XTR-727807 https://reactome.org/PathwayBrowser/#/R-XTR-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Xenopus tropicalis 57812 R-XTR-9603987 https://reactome.org/PathwayBrowser/#/R-XTR-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Xenopus tropicalis 57812 R-XTR-9603991 https://reactome.org/PathwayBrowser/#/R-XTR-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Xenopus tropicalis 57812 R-XTR-9605600 https://reactome.org/PathwayBrowser/#/R-XTR-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Xenopus tropicalis 57812 R-XTR-977071 https://reactome.org/PathwayBrowser/#/R-XTR-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Xenopus tropicalis 57812 R-XTR-981497 https://reactome.org/PathwayBrowser/#/R-XTR-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Xenopus tropicalis 57812 R-XTR-981809 https://reactome.org/PathwayBrowser/#/R-XTR-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Xenopus tropicalis 57812 R-XTR-9845538 https://reactome.org/PathwayBrowser/#/R-XTR-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Xenopus tropicalis 57812 R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 57812 R-XTR-9846305 https://reactome.org/PathwayBrowser/#/R-XTR-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Xenopus tropicalis 57834 R-BTA-141341 https://reactome.org/PathwayBrowser/#/R-BTA-141341 SMOX-3 oxidises SPN to SPM IEA Bos taurus 57834 R-BTA-141351 https://reactome.org/PathwayBrowser/#/R-BTA-141351 PAOX:FAD oxidises NASPN to SPM IEA Bos taurus 57834 R-BTA-204617 https://reactome.org/PathwayBrowser/#/R-BTA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Bos taurus 57834 R-BTA-204647 https://reactome.org/PathwayBrowser/#/R-BTA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Bos taurus 57834 R-BTA-351208 https://reactome.org/PathwayBrowser/#/R-BTA-351208 Spermidine => N-acetylated spermidine IEA Bos taurus 57834 R-BTA-351210 https://reactome.org/PathwayBrowser/#/R-BTA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Bos taurus 57834 R-BTA-351215 https://reactome.org/PathwayBrowser/#/R-BTA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Bos taurus 57834 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 57834 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 57834 R-CEL-141351 https://reactome.org/PathwayBrowser/#/R-CEL-141351 PAOX:FAD oxidises NASPN to SPM IEA Caenorhabditis elegans 57834 R-CEL-204617 https://reactome.org/PathwayBrowser/#/R-CEL-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Caenorhabditis elegans 57834 R-CEL-204647 https://reactome.org/PathwayBrowser/#/R-CEL-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Caenorhabditis elegans 57834 R-CEL-351208 https://reactome.org/PathwayBrowser/#/R-CEL-351208 Spermidine => N-acetylated spermidine IEA Caenorhabditis elegans 57834 R-CEL-351215 https://reactome.org/PathwayBrowser/#/R-CEL-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Caenorhabditis elegans 57834 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 57834 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 57834 R-CFA-141341 https://reactome.org/PathwayBrowser/#/R-CFA-141341 SMOX-3 oxidises SPN to SPM IEA Canis familiaris 57834 R-CFA-141351 https://reactome.org/PathwayBrowser/#/R-CFA-141351 PAOX:FAD oxidises NASPN to SPM IEA Canis familiaris 57834 R-CFA-204617 https://reactome.org/PathwayBrowser/#/R-CFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Canis familiaris 57834 R-CFA-204647 https://reactome.org/PathwayBrowser/#/R-CFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Canis familiaris 57834 R-CFA-351208 https://reactome.org/PathwayBrowser/#/R-CFA-351208 Spermidine => N-acetylated spermidine IEA Canis familiaris 57834 R-CFA-351210 https://reactome.org/PathwayBrowser/#/R-CFA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Canis familiaris 57834 R-CFA-351215 https://reactome.org/PathwayBrowser/#/R-CFA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Canis familiaris 57834 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 57834 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 57834 R-DDI-204617 https://reactome.org/PathwayBrowser/#/R-DDI-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Dictyostelium discoideum 57834 R-DDI-204647 https://reactome.org/PathwayBrowser/#/R-DDI-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Dictyostelium discoideum 57834 R-DDI-351208 https://reactome.org/PathwayBrowser/#/R-DDI-351208 Spermidine => N-acetylated spermidine IEA Dictyostelium discoideum 57834 R-DDI-351215 https://reactome.org/PathwayBrowser/#/R-DDI-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Dictyostelium discoideum 57834 R-DME-141341 https://reactome.org/PathwayBrowser/#/R-DME-141341 SMOX-3 oxidises SPN to SPM IEA Drosophila melanogaster 57834 R-DME-141351 https://reactome.org/PathwayBrowser/#/R-DME-141351 PAOX:FAD oxidises NASPN to SPM IEA Drosophila melanogaster 57834 R-DME-204617 https://reactome.org/PathwayBrowser/#/R-DME-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Drosophila melanogaster 57834 R-DME-204647 https://reactome.org/PathwayBrowser/#/R-DME-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Drosophila melanogaster 57834 R-DME-351208 https://reactome.org/PathwayBrowser/#/R-DME-351208 Spermidine => N-acetylated spermidine IEA Drosophila melanogaster 57834 R-DME-351210 https://reactome.org/PathwayBrowser/#/R-DME-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Drosophila melanogaster 57834 R-DME-351215 https://reactome.org/PathwayBrowser/#/R-DME-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Drosophila melanogaster 57834 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 57834 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 57834 R-DRE-141351 https://reactome.org/PathwayBrowser/#/R-DRE-141351 PAOX:FAD oxidises NASPN to SPM IEA Danio rerio 57834 R-DRE-204617 https://reactome.org/PathwayBrowser/#/R-DRE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Danio rerio 57834 R-DRE-204647 https://reactome.org/PathwayBrowser/#/R-DRE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Danio rerio 57834 R-DRE-351208 https://reactome.org/PathwayBrowser/#/R-DRE-351208 Spermidine => N-acetylated spermidine IEA Danio rerio 57834 R-DRE-351210 https://reactome.org/PathwayBrowser/#/R-DRE-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Danio rerio 57834 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 57834 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 57834 R-GGA-141341 https://reactome.org/PathwayBrowser/#/R-GGA-141341 SMOX-3 oxidises SPN to SPM IEA Gallus gallus 57834 R-GGA-141351 https://reactome.org/PathwayBrowser/#/R-GGA-141351 PAOX:FAD oxidises NASPN to SPM IEA Gallus gallus 57834 R-GGA-351208 https://reactome.org/PathwayBrowser/#/R-GGA-351208 Spermidine => N-acetylated spermidine IEA Gallus gallus 57834 R-GGA-351210 https://reactome.org/PathwayBrowser/#/R-GGA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Gallus gallus 57834 R-GGA-351215 https://reactome.org/PathwayBrowser/#/R-GGA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Gallus gallus 57834 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 57834 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 57834 R-HSA-141341 https://reactome.org/PathwayBrowser/#/R-HSA-141341 SMOX-3 oxidises SPN to SPM TAS Homo sapiens 57834 R-HSA-141351 https://reactome.org/PathwayBrowser/#/R-HSA-141351 PAOX:FAD oxidises NASPN to SPM TAS Homo sapiens 57834 R-HSA-204617 https://reactome.org/PathwayBrowser/#/R-HSA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A TAS Homo sapiens 57834 R-HSA-204647 https://reactome.org/PathwayBrowser/#/R-HSA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine TAS Homo sapiens 57834 R-HSA-351208 https://reactome.org/PathwayBrowser/#/R-HSA-351208 Spermidine => N-acetylated spermidine TAS Homo sapiens 57834 R-HSA-351210 https://reactome.org/PathwayBrowser/#/R-HSA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine TAS Homo sapiens 57834 R-HSA-351215 https://reactome.org/PathwayBrowser/#/R-HSA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine TAS Homo sapiens 57834 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 57834 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 57834 R-MMU-141341 https://reactome.org/PathwayBrowser/#/R-MMU-141341 SMOX-3 oxidises SPN to SPM IEA Mus musculus 57834 R-MMU-141351 https://reactome.org/PathwayBrowser/#/R-MMU-141351 PAOX:FAD oxidises NASPN to SPM IEA Mus musculus 57834 R-MMU-204617 https://reactome.org/PathwayBrowser/#/R-MMU-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Mus musculus 57834 R-MMU-204647 https://reactome.org/PathwayBrowser/#/R-MMU-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Mus musculus 57834 R-MMU-351208 https://reactome.org/PathwayBrowser/#/R-MMU-351208 Spermidine => N-acetylated spermidine IEA Mus musculus 57834 R-MMU-351210 https://reactome.org/PathwayBrowser/#/R-MMU-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Mus musculus 57834 R-MMU-351215 https://reactome.org/PathwayBrowser/#/R-MMU-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Mus musculus 57834 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 57834 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 57834 R-PFA-204617 https://reactome.org/PathwayBrowser/#/R-PFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Plasmodium falciparum 57834 R-PFA-204647 https://reactome.org/PathwayBrowser/#/R-PFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Plasmodium falciparum 57834 R-PFA-351215 https://reactome.org/PathwayBrowser/#/R-PFA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Plasmodium falciparum 57834 R-RNO-141341 https://reactome.org/PathwayBrowser/#/R-RNO-141341 SMOX-3 oxidises SPN to SPM IEA Rattus norvegicus 57834 R-RNO-141351 https://reactome.org/PathwayBrowser/#/R-RNO-141351 PAOX:FAD oxidises NASPN to SPM IEA Rattus norvegicus 57834 R-RNO-204617 https://reactome.org/PathwayBrowser/#/R-RNO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Rattus norvegicus 57834 R-RNO-204647 https://reactome.org/PathwayBrowser/#/R-RNO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Rattus norvegicus 57834 R-RNO-351208 https://reactome.org/PathwayBrowser/#/R-RNO-351208 Spermidine => N-acetylated spermidine IEA Rattus norvegicus 57834 R-RNO-351210 https://reactome.org/PathwayBrowser/#/R-RNO-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Rattus norvegicus 57834 R-RNO-351215 https://reactome.org/PathwayBrowser/#/R-RNO-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Rattus norvegicus 57834 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 57834 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 57834 R-SCE-204617 https://reactome.org/PathwayBrowser/#/R-SCE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Saccharomyces cerevisiae 57834 R-SCE-204647 https://reactome.org/PathwayBrowser/#/R-SCE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Saccharomyces cerevisiae 57834 R-SCE-351208 https://reactome.org/PathwayBrowser/#/R-SCE-351208 Spermidine => N-acetylated spermidine IEA Saccharomyces cerevisiae 57834 R-SCE-351215 https://reactome.org/PathwayBrowser/#/R-SCE-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Saccharomyces cerevisiae 57834 R-SPO-204617 https://reactome.org/PathwayBrowser/#/R-SPO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Schizosaccharomyces pombe 57834 R-SPO-204647 https://reactome.org/PathwayBrowser/#/R-SPO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Schizosaccharomyces pombe 57834 R-SPO-351208 https://reactome.org/PathwayBrowser/#/R-SPO-351208 Spermidine => N-acetylated spermidine IEA Schizosaccharomyces pombe 57834 R-SPO-351215 https://reactome.org/PathwayBrowser/#/R-SPO-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Schizosaccharomyces pombe 57834 R-SSC-141341 https://reactome.org/PathwayBrowser/#/R-SSC-141341 SMOX-3 oxidises SPN to SPM IEA Sus scrofa 57834 R-SSC-141351 https://reactome.org/PathwayBrowser/#/R-SSC-141351 PAOX:FAD oxidises NASPN to SPM IEA Sus scrofa 57834 R-SSC-204617 https://reactome.org/PathwayBrowser/#/R-SSC-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Sus scrofa 57834 R-SSC-204647 https://reactome.org/PathwayBrowser/#/R-SSC-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Sus scrofa 57834 R-SSC-351208 https://reactome.org/PathwayBrowser/#/R-SSC-351208 Spermidine => N-acetylated spermidine IEA Sus scrofa 57834 R-SSC-351210 https://reactome.org/PathwayBrowser/#/R-SSC-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Sus scrofa 57834 R-SSC-351215 https://reactome.org/PathwayBrowser/#/R-SSC-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Sus scrofa 57834 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 57834 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 57834 R-XTR-141341 https://reactome.org/PathwayBrowser/#/R-XTR-141341 SMOX-3 oxidises SPN to SPM IEA Xenopus tropicalis 57834 R-XTR-204617 https://reactome.org/PathwayBrowser/#/R-XTR-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Xenopus tropicalis 57834 R-XTR-204647 https://reactome.org/PathwayBrowser/#/R-XTR-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Xenopus tropicalis 57834 R-XTR-351208 https://reactome.org/PathwayBrowser/#/R-XTR-351208 Spermidine => N-acetylated spermidine IEA Xenopus tropicalis 57834 R-XTR-351210 https://reactome.org/PathwayBrowser/#/R-XTR-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Xenopus tropicalis 57834 R-XTR-351215 https://reactome.org/PathwayBrowser/#/R-XTR-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Xenopus tropicalis 57834 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 57834 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 57836 R-BTA-109699 https://reactome.org/PathwayBrowser/#/R-BTA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-109700 https://reactome.org/PathwayBrowser/#/R-BTA-109700 AKT2 binds PIP3 IEA Bos taurus 57836 R-BTA-109701 https://reactome.org/PathwayBrowser/#/R-BTA-109701 PDPK1 binds PIP3 IEA Bos taurus 57836 R-BTA-109702 https://reactome.org/PathwayBrowser/#/R-BTA-109702 PDPK1 phosphorylates AKT2 IEA Bos taurus 57836 R-BTA-1112666 https://reactome.org/PathwayBrowser/#/R-BTA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Bos taurus 57836 R-BTA-1250370 https://reactome.org/PathwayBrowser/#/R-BTA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Bos taurus 57836 R-BTA-1250462 https://reactome.org/PathwayBrowser/#/R-BTA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Bos taurus 57836 R-BTA-1306957 https://reactome.org/PathwayBrowser/#/R-BTA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Bos taurus 57836 R-BTA-1306979 https://reactome.org/PathwayBrowser/#/R-BTA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Bos taurus 57836 R-BTA-1433415 https://reactome.org/PathwayBrowser/#/R-BTA-1433415 Activation of RAC1 IEA Bos taurus 57836 R-BTA-1433514 https://reactome.org/PathwayBrowser/#/R-BTA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Bos taurus 57836 R-BTA-1433542 https://reactome.org/PathwayBrowser/#/R-BTA-1433542 Phosphorylation and activation of VAV1 IEA Bos taurus 57836 R-BTA-165162 https://reactome.org/PathwayBrowser/#/R-BTA-165162 Phosphorylation of TSC2 by PKB IEA Bos taurus 57836 R-BTA-165182 https://reactome.org/PathwayBrowser/#/R-BTA-165182 Phosphorylation of complexed TSC2 by PKB IEA Bos taurus 57836 R-BTA-1675773 https://reactome.org/PathwayBrowser/#/R-BTA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Bos taurus 57836 R-BTA-1675949 https://reactome.org/PathwayBrowser/#/R-BTA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Bos taurus 57836 R-BTA-1676048 https://reactome.org/PathwayBrowser/#/R-BTA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Bos taurus 57836 R-BTA-177923 https://reactome.org/PathwayBrowser/#/R-BTA-177923 Sustained activation of SRC kinase by SHP2 IEA Bos taurus 57836 R-BTA-177924 https://reactome.org/PathwayBrowser/#/R-BTA-177924 Dephosphorylation of Gab1 by SHP2 IEA Bos taurus 57836 R-BTA-177926 https://reactome.org/PathwayBrowser/#/R-BTA-177926 Dephosphorylation of PAG by SHP2 IEA Bos taurus 57836 R-BTA-177927 https://reactome.org/PathwayBrowser/#/R-BTA-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Bos taurus 57836 R-BTA-177930 https://reactome.org/PathwayBrowser/#/R-BTA-177930 GAB1 phosphorylation by EGFR kinase IEA Bos taurus 57836 R-BTA-177935 https://reactome.org/PathwayBrowser/#/R-BTA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Bos taurus 57836 R-BTA-177939 https://reactome.org/PathwayBrowser/#/R-BTA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Bos taurus 57836 R-BTA-177941 https://reactome.org/PathwayBrowser/#/R-BTA-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Bos taurus 57836 R-BTA-177944 https://reactome.org/PathwayBrowser/#/R-BTA-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Bos taurus 57836 R-BTA-179467 https://reactome.org/PathwayBrowser/#/R-BTA-179467 GAB1 binds phosphatidylinositol-3,4,5-trisphosphate IEA Bos taurus 57836 R-BTA-186800 https://reactome.org/PathwayBrowser/#/R-BTA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-198266 https://reactome.org/PathwayBrowser/#/R-BTA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Bos taurus 57836 R-BTA-199456 https://reactome.org/PathwayBrowser/#/R-BTA-199456 PTEN dephosphorylates PIP3 IEA Bos taurus 57836 R-BTA-201510 https://reactome.org/PathwayBrowser/#/R-BTA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Bos taurus 57836 R-BTA-202164 https://reactome.org/PathwayBrowser/#/R-BTA-202164 Translocation of PDK1 to Plasma membrane IEA Bos taurus 57836 R-BTA-202222 https://reactome.org/PathwayBrowser/#/R-BTA-202222 Phosphorylation of PKC theta IEA Bos taurus 57836 R-BTA-202237 https://reactome.org/PathwayBrowser/#/R-BTA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Bos taurus 57836 R-BTA-202365 https://reactome.org/PathwayBrowser/#/R-BTA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-202394 https://reactome.org/PathwayBrowser/#/R-BTA-202394 Translocation of CARMA1 to Plasma membrane IEA Bos taurus 57836 R-BTA-202437 https://reactome.org/PathwayBrowser/#/R-BTA-202437 Phosphorylation of CARMA1 IEA Bos taurus 57836 R-BTA-202443 https://reactome.org/PathwayBrowser/#/R-BTA-202443 Oligomerization of CARMA1 IEA Bos taurus 57836 R-BTA-202459 https://reactome.org/PathwayBrowser/#/R-BTA-202459 Phosphorylation of Bcl10 IEA Bos taurus 57836 R-BTA-202466 https://reactome.org/PathwayBrowser/#/R-BTA-202466 Interaction of Bcl10 to CARMA1 IEA Bos taurus 57836 R-BTA-202472 https://reactome.org/PathwayBrowser/#/R-BTA-202472 Translocation of TRAF6 to CBM complex IEA Bos taurus 57836 R-BTA-202478 https://reactome.org/PathwayBrowser/#/R-BTA-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Bos taurus 57836 R-BTA-202489 https://reactome.org/PathwayBrowser/#/R-BTA-202489 Oligomerization of Bcl10 IEA Bos taurus 57836 R-BTA-202500 https://reactome.org/PathwayBrowser/#/R-BTA-202500 Activation of IKK complex IEA Bos taurus 57836 R-BTA-202510 https://reactome.org/PathwayBrowser/#/R-BTA-202510 Activation of TAK1-TAB2 complex IEA Bos taurus 57836 R-BTA-202692 https://reactome.org/PathwayBrowser/#/R-BTA-202692 PIP3 binds to RhoA and activates it IEA Bos taurus 57836 R-BTA-2029268 https://reactome.org/PathwayBrowser/#/R-BTA-2029268 Phosphorylation and activation of PLCG IEA Bos taurus 57836 R-BTA-2029271 https://reactome.org/PathwayBrowser/#/R-BTA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-2029272 https://reactome.org/PathwayBrowser/#/R-BTA-2029272 Release of PLCG from FCGR IEA Bos taurus 57836 R-BTA-2029453 https://reactome.org/PathwayBrowser/#/R-BTA-2029453 Phosphorylation of VAV IEA Bos taurus 57836 R-BTA-2029458 https://reactome.org/PathwayBrowser/#/R-BTA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Bos taurus 57836 R-BTA-2029465 https://reactome.org/PathwayBrowser/#/R-BTA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Bos taurus 57836 R-BTA-2029466 https://reactome.org/PathwayBrowser/#/R-BTA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Bos taurus 57836 R-BTA-2029469 https://reactome.org/PathwayBrowser/#/R-BTA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Bos taurus 57836 R-BTA-2045911 https://reactome.org/PathwayBrowser/#/R-BTA-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Bos taurus 57836 R-BTA-2076220 https://reactome.org/PathwayBrowser/#/R-BTA-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Bos taurus 57836 R-BTA-2130194 https://reactome.org/PathwayBrowser/#/R-BTA-2130194 ABL phosphorylates WAVEs IEA Bos taurus 57836 R-BTA-2197690 https://reactome.org/PathwayBrowser/#/R-BTA-2197690 Detachment of WASP/WAVE IEA Bos taurus 57836 R-BTA-2316429 https://reactome.org/PathwayBrowser/#/R-BTA-2316429 PIP3 recruits PDPK1 to the membrane IEA Bos taurus 57836 R-BTA-2316434 https://reactome.org/PathwayBrowser/#/R-BTA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-2424476 https://reactome.org/PathwayBrowser/#/R-BTA-2424476 Activation of RAC1 by VAV2/3 IEA Bos taurus 57836 R-BTA-2424480 https://reactome.org/PathwayBrowser/#/R-BTA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-2424481 https://reactome.org/PathwayBrowser/#/R-BTA-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Bos taurus 57836 R-BTA-2424485 https://reactome.org/PathwayBrowser/#/R-BTA-2424485 Release of p-PLCG1 IEA Bos taurus 57836 R-BTA-2424487 https://reactome.org/PathwayBrowser/#/R-BTA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Bos taurus 57836 R-BTA-2730833 https://reactome.org/PathwayBrowser/#/R-BTA-2730833 Phosphorylation of TEC kinases by p-SYK IEA Bos taurus 57836 R-BTA-2730840 https://reactome.org/PathwayBrowser/#/R-BTA-2730840 Activation of RAC1 by VAV IEA Bos taurus 57836 R-BTA-2730841 https://reactome.org/PathwayBrowser/#/R-BTA-2730841 Phosphorylation and activation of VAV IEA Bos taurus 57836 R-BTA-2730842 https://reactome.org/PathwayBrowser/#/R-BTA-2730842 PI3K associates with phosphorylated GAB2 IEA Bos taurus 57836 R-BTA-2730847 https://reactome.org/PathwayBrowser/#/R-BTA-2730847 Hydrolysis of PIP2 by PLCG IEA Bos taurus 57836 R-BTA-2730856 https://reactome.org/PathwayBrowser/#/R-BTA-2730856 Autophosphorylation of PAK IEA Bos taurus 57836 R-BTA-2730858 https://reactome.org/PathwayBrowser/#/R-BTA-2730858 Autophosphorylation of BTK/ITK IEA Bos taurus 57836 R-BTA-2730870 https://reactome.org/PathwayBrowser/#/R-BTA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Bos taurus 57836 R-BTA-2730889 https://reactome.org/PathwayBrowser/#/R-BTA-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Bos taurus 57836 R-BTA-389158 https://reactome.org/PathwayBrowser/#/R-BTA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-389348 https://reactome.org/PathwayBrowser/#/R-BTA-389348 Activation of Rac1 by pVav1 IEA Bos taurus 57836 R-BTA-389350 https://reactome.org/PathwayBrowser/#/R-BTA-389350 Activation of Cdc42 by pVav1 IEA Bos taurus 57836 R-BTA-389352 https://reactome.org/PathwayBrowser/#/R-BTA-389352 Translocation of Vav1 to CD28 IEA Bos taurus 57836 R-BTA-389354 https://reactome.org/PathwayBrowser/#/R-BTA-389354 Activation of Vav1 IEA Bos taurus 57836 R-BTA-392300 https://reactome.org/PathwayBrowser/#/R-BTA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-437162 https://reactome.org/PathwayBrowser/#/R-BTA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-442273 https://reactome.org/PathwayBrowser/#/R-BTA-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Bos taurus 57836 R-BTA-449058 https://reactome.org/PathwayBrowser/#/R-BTA-449058 Interleukin-1 family are secreted IEA Bos taurus 57836 R-BTA-5218819 https://reactome.org/PathwayBrowser/#/R-BTA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-5218820 https://reactome.org/PathwayBrowser/#/R-BTA-5218820 Src kinases phosphorylate VAV IEA Bos taurus 57836 R-BTA-5218850 https://reactome.org/PathwayBrowser/#/R-BTA-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Bos taurus 57836 R-BTA-5357445 https://reactome.org/PathwayBrowser/#/R-BTA-5357445 PAK1-3 dimer disassociates IEA Bos taurus 57836 R-BTA-5357472 https://reactome.org/PathwayBrowser/#/R-BTA-5357472 PAK1-3 autophosphorylates IEA Bos taurus 57836 R-BTA-5357483 https://reactome.org/PathwayBrowser/#/R-BTA-5357483 RAC1 binds PAK1-3 IEA Bos taurus 57836 R-BTA-5620975 https://reactome.org/PathwayBrowser/#/R-BTA-5620975 MLKL binds PIPs IEA Bos taurus 57836 R-BTA-5623632 https://reactome.org/PathwayBrowser/#/R-BTA-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Bos taurus 57836 R-BTA-5623667 https://reactome.org/PathwayBrowser/#/R-BTA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Bos taurus 57836 R-BTA-5654147 https://reactome.org/PathwayBrowser/#/R-BTA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Bos taurus 57836 R-BTA-5654149 https://reactome.org/PathwayBrowser/#/R-BTA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Bos taurus 57836 R-BTA-5654151 https://reactome.org/PathwayBrowser/#/R-BTA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Bos taurus 57836 R-BTA-5654159 https://reactome.org/PathwayBrowser/#/R-BTA-5654159 Activated FGFR2 binds PLCG1 IEA Bos taurus 57836 R-BTA-5654163 https://reactome.org/PathwayBrowser/#/R-BTA-5654163 Activated FGFR4 binds PLCG1 IEA Bos taurus 57836 R-BTA-5654167 https://reactome.org/PathwayBrowser/#/R-BTA-5654167 Activated FGFR1 binds PLCG1 IEA Bos taurus 57836 R-BTA-5654222 https://reactome.org/PathwayBrowser/#/R-BTA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Bos taurus 57836 R-BTA-5654224 https://reactome.org/PathwayBrowser/#/R-BTA-5654224 Activated FGFR3 binds PLCG1 IEA Bos taurus 57836 R-BTA-5654690 https://reactome.org/PathwayBrowser/#/R-BTA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-5654692 https://reactome.org/PathwayBrowser/#/R-BTA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-5654697 https://reactome.org/PathwayBrowser/#/R-BTA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-5654701 https://reactome.org/PathwayBrowser/#/R-BTA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-5654705 https://reactome.org/PathwayBrowser/#/R-BTA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-5654709 https://reactome.org/PathwayBrowser/#/R-BTA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-5654714 https://reactome.org/PathwayBrowser/#/R-BTA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-5654717 https://reactome.org/PathwayBrowser/#/R-BTA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-6805981 https://reactome.org/PathwayBrowser/#/R-BTA-6805981 HMGB1 release from cells IEA Bos taurus 57836 R-BTA-8849969 https://reactome.org/PathwayBrowser/#/R-BTA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Bos taurus 57836 R-BTA-8852019 https://reactome.org/PathwayBrowser/#/R-BTA-8852019 MET bound PI3K generates PIP3 IEA Bos taurus 57836 R-BTA-8874470 https://reactome.org/PathwayBrowser/#/R-BTA-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Bos taurus 57836 R-BTA-8951586 https://reactome.org/PathwayBrowser/#/R-BTA-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Bos taurus 57836 R-BTA-8964241 https://reactome.org/PathwayBrowser/#/R-BTA-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Bos taurus 57836 R-BTA-8964271 https://reactome.org/PathwayBrowser/#/R-BTA-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Bos taurus 57836 R-BTA-8964317 https://reactome.org/PathwayBrowser/#/R-BTA-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Bos taurus 57836 R-BTA-9021627 https://reactome.org/PathwayBrowser/#/R-BTA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 57836 R-BTA-917693 https://reactome.org/PathwayBrowser/#/R-BTA-917693 ESCRT Disassembly IEA Bos taurus 57836 R-BTA-917696 https://reactome.org/PathwayBrowser/#/R-BTA-917696 Cargo Sequestration IEA Bos taurus 57836 R-BTA-917700 https://reactome.org/PathwayBrowser/#/R-BTA-917700 MVB Vesicle Formation IEA Bos taurus 57836 R-BTA-917730 https://reactome.org/PathwayBrowser/#/R-BTA-917730 Cargo Recognition And Sorting IEA Bos taurus 57836 R-BTA-9606151 https://reactome.org/PathwayBrowser/#/R-BTA-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Bos taurus 57836 R-BTA-9606884 https://reactome.org/PathwayBrowser/#/R-BTA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Bos taurus 57836 R-BTA-9606894 https://reactome.org/PathwayBrowser/#/R-BTA-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Bos taurus 57836 R-BTA-9632858 https://reactome.org/PathwayBrowser/#/R-BTA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Bos taurus 57836 R-BTA-9632906 https://reactome.org/PathwayBrowser/#/R-BTA-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Bos taurus 57836 R-BTA-9632910 https://reactome.org/PathwayBrowser/#/R-BTA-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Bos taurus 57836 R-BTA-9632918 https://reactome.org/PathwayBrowser/#/R-BTA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Bos taurus 57836 R-BTA-9647619 https://reactome.org/PathwayBrowser/#/R-BTA-9647619 GSDMD forms ring‐shaped oligomers IEA Bos taurus 57836 R-BTA-9647631 https://reactome.org/PathwayBrowser/#/R-BTA-9647631 GSDMD (1-275) binds PIPs IEA Bos taurus 57836 R-BTA-9647645 https://reactome.org/PathwayBrowser/#/R-BTA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Bos taurus 57836 R-BTA-9647660 https://reactome.org/PathwayBrowser/#/R-BTA-9647660 GSDME (1-270) binds PIPs IEA Bos taurus 57836 R-BTA-9691421 https://reactome.org/PathwayBrowser/#/R-BTA-9691421 BTK binds BTK inhibitors IEA Bos taurus 57836 R-BTA-9700149 https://reactome.org/PathwayBrowser/#/R-BTA-9700149 Active ALK binds PLCG1 IEA Bos taurus 57836 R-BTA-9700171 https://reactome.org/PathwayBrowser/#/R-BTA-9700171 Active ALK phosphorylates PLCG1 IEA Bos taurus 57836 R-BTA-9710254 https://reactome.org/PathwayBrowser/#/R-BTA-9710254 GSDME oligomerizes IEA Bos taurus 57836 R-CEL-109700 https://reactome.org/PathwayBrowser/#/R-CEL-109700 AKT2 binds PIP3 IEA Caenorhabditis elegans 57836 R-CEL-109701 https://reactome.org/PathwayBrowser/#/R-CEL-109701 PDPK1 binds PIP3 IEA Caenorhabditis elegans 57836 R-CEL-109702 https://reactome.org/PathwayBrowser/#/R-CEL-109702 PDPK1 phosphorylates AKT2 IEA Caenorhabditis elegans 57836 R-CEL-1250370 https://reactome.org/PathwayBrowser/#/R-CEL-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Caenorhabditis elegans 57836 R-CEL-1250462 https://reactome.org/PathwayBrowser/#/R-CEL-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Caenorhabditis elegans 57836 R-CEL-1306957 https://reactome.org/PathwayBrowser/#/R-CEL-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Caenorhabditis elegans 57836 R-CEL-1306979 https://reactome.org/PathwayBrowser/#/R-CEL-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Caenorhabditis elegans 57836 R-CEL-1433415 https://reactome.org/PathwayBrowser/#/R-CEL-1433415 Activation of RAC1 IEA Caenorhabditis elegans 57836 R-CEL-1433514 https://reactome.org/PathwayBrowser/#/R-CEL-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Caenorhabditis elegans 57836 R-CEL-1675773 https://reactome.org/PathwayBrowser/#/R-CEL-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Caenorhabditis elegans 57836 R-CEL-1675949 https://reactome.org/PathwayBrowser/#/R-CEL-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Caenorhabditis elegans 57836 R-CEL-1676048 https://reactome.org/PathwayBrowser/#/R-CEL-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Caenorhabditis elegans 57836 R-CEL-177939 https://reactome.org/PathwayBrowser/#/R-CEL-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Caenorhabditis elegans 57836 R-CEL-186800 https://reactome.org/PathwayBrowser/#/R-CEL-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Caenorhabditis elegans 57836 R-CEL-198640 https://reactome.org/PathwayBrowser/#/R-CEL-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Caenorhabditis elegans 57836 R-CEL-199443 https://reactome.org/PathwayBrowser/#/R-CEL-199443 THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation IEA Caenorhabditis elegans 57836 R-CEL-199456 https://reactome.org/PathwayBrowser/#/R-CEL-199456 PTEN dephosphorylates PIP3 IEA Caenorhabditis elegans 57836 R-CEL-201510 https://reactome.org/PathwayBrowser/#/R-CEL-201510 PI3K synthesizes PIP3 downstream of ALK IEA Caenorhabditis elegans 57836 R-CEL-202164 https://reactome.org/PathwayBrowser/#/R-CEL-202164 Translocation of PDK1 to Plasma membrane IEA Caenorhabditis elegans 57836 R-CEL-202222 https://reactome.org/PathwayBrowser/#/R-CEL-202222 Phosphorylation of PKC theta IEA Caenorhabditis elegans 57836 R-CEL-202692 https://reactome.org/PathwayBrowser/#/R-CEL-202692 PIP3 binds to RhoA and activates it IEA Caenorhabditis elegans 57836 R-CEL-2029466 https://reactome.org/PathwayBrowser/#/R-CEL-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Caenorhabditis elegans 57836 R-CEL-2029469 https://reactome.org/PathwayBrowser/#/R-CEL-2029469 p-ERK phosphorylates WAVEs and ABI IEA Caenorhabditis elegans 57836 R-CEL-2130194 https://reactome.org/PathwayBrowser/#/R-CEL-2130194 ABL phosphorylates WAVEs IEA Caenorhabditis elegans 57836 R-CEL-2197690 https://reactome.org/PathwayBrowser/#/R-CEL-2197690 Detachment of WASP/WAVE IEA Caenorhabditis elegans 57836 R-CEL-2316429 https://reactome.org/PathwayBrowser/#/R-CEL-2316429 PIP3 recruits PDPK1 to the membrane IEA Caenorhabditis elegans 57836 R-CEL-2316434 https://reactome.org/PathwayBrowser/#/R-CEL-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 57836 R-CEL-2317314 https://reactome.org/PathwayBrowser/#/R-CEL-2317314 AKT binds PDPK1 IEA Caenorhabditis elegans 57836 R-CEL-2317332 https://reactome.org/PathwayBrowser/#/R-CEL-2317332 PIP3 recruits AKT to the membrane IEA Caenorhabditis elegans 57836 R-CEL-437162 https://reactome.org/PathwayBrowser/#/R-CEL-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Caenorhabditis elegans 57836 R-CEL-442273 https://reactome.org/PathwayBrowser/#/R-CEL-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Caenorhabditis elegans 57836 R-CEL-5218819 https://reactome.org/PathwayBrowser/#/R-CEL-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 57836 R-CEL-5218850 https://reactome.org/PathwayBrowser/#/R-CEL-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 57836 R-CEL-5357445 https://reactome.org/PathwayBrowser/#/R-CEL-5357445 PAK1-3 dimer disassociates IEA Caenorhabditis elegans 57836 R-CEL-5357472 https://reactome.org/PathwayBrowser/#/R-CEL-5357472 PAK1-3 autophosphorylates IEA Caenorhabditis elegans 57836 R-CEL-5357483 https://reactome.org/PathwayBrowser/#/R-CEL-5357483 RAC1 binds PAK1-3 IEA Caenorhabditis elegans 57836 R-CEL-5623632 https://reactome.org/PathwayBrowser/#/R-CEL-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Caenorhabditis elegans 57836 R-CEL-5623667 https://reactome.org/PathwayBrowser/#/R-CEL-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Caenorhabditis elegans 57836 R-CEL-5654149 https://reactome.org/PathwayBrowser/#/R-CEL-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Caenorhabditis elegans 57836 R-CEL-5654151 https://reactome.org/PathwayBrowser/#/R-CEL-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Caenorhabditis elegans 57836 R-CEL-5654690 https://reactome.org/PathwayBrowser/#/R-CEL-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 57836 R-CEL-5654717 https://reactome.org/PathwayBrowser/#/R-CEL-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 57836 R-CEL-6795473 https://reactome.org/PathwayBrowser/#/R-CEL-6795473 PDPK1 phosphorylates SGK1 IEA Caenorhabditis elegans 57836 R-CEL-8849969 https://reactome.org/PathwayBrowser/#/R-CEL-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Caenorhabditis elegans 57836 R-CEL-8852019 https://reactome.org/PathwayBrowser/#/R-CEL-8852019 MET bound PI3K generates PIP3 IEA Caenorhabditis elegans 57836 R-CEL-8951586 https://reactome.org/PathwayBrowser/#/R-CEL-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Caenorhabditis elegans 57836 R-CEL-917696 https://reactome.org/PathwayBrowser/#/R-CEL-917696 Cargo Sequestration IEA Caenorhabditis elegans 57836 R-CEL-917700 https://reactome.org/PathwayBrowser/#/R-CEL-917700 MVB Vesicle Formation IEA Caenorhabditis elegans 57836 R-CEL-917730 https://reactome.org/PathwayBrowser/#/R-CEL-917730 Cargo Recognition And Sorting IEA Caenorhabditis elegans 57836 R-CEL-9603279 https://reactome.org/PathwayBrowser/#/R-CEL-9603279 PIP3 recruits PDK1 and AKT to the membrane IEA Caenorhabditis elegans 57836 R-CEL-9632858 https://reactome.org/PathwayBrowser/#/R-CEL-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Caenorhabditis elegans 57836 R-CEL-9632906 https://reactome.org/PathwayBrowser/#/R-CEL-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Caenorhabditis elegans 57836 R-CEL-9632910 https://reactome.org/PathwayBrowser/#/R-CEL-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Caenorhabditis elegans 57836 R-CEL-9632918 https://reactome.org/PathwayBrowser/#/R-CEL-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Caenorhabditis elegans 57836 R-CFA-109699 https://reactome.org/PathwayBrowser/#/R-CFA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-109701 https://reactome.org/PathwayBrowser/#/R-CFA-109701 PDPK1 binds PIP3 IEA Canis familiaris 57836 R-CFA-1112666 https://reactome.org/PathwayBrowser/#/R-CFA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Canis familiaris 57836 R-CFA-1250370 https://reactome.org/PathwayBrowser/#/R-CFA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Canis familiaris 57836 R-CFA-1250462 https://reactome.org/PathwayBrowser/#/R-CFA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Canis familiaris 57836 R-CFA-1306957 https://reactome.org/PathwayBrowser/#/R-CFA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Canis familiaris 57836 R-CFA-1306979 https://reactome.org/PathwayBrowser/#/R-CFA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Canis familiaris 57836 R-CFA-1433415 https://reactome.org/PathwayBrowser/#/R-CFA-1433415 Activation of RAC1 IEA Canis familiaris 57836 R-CFA-1433514 https://reactome.org/PathwayBrowser/#/R-CFA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Canis familiaris 57836 R-CFA-1433542 https://reactome.org/PathwayBrowser/#/R-CFA-1433542 Phosphorylation and activation of VAV1 IEA Canis familiaris 57836 R-CFA-1675773 https://reactome.org/PathwayBrowser/#/R-CFA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Canis familiaris 57836 R-CFA-1675949 https://reactome.org/PathwayBrowser/#/R-CFA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Canis familiaris 57836 R-CFA-1676048 https://reactome.org/PathwayBrowser/#/R-CFA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Canis familiaris 57836 R-CFA-177923 https://reactome.org/PathwayBrowser/#/R-CFA-177923 Sustained activation of SRC kinase by SHP2 IEA Canis familiaris 57836 R-CFA-177924 https://reactome.org/PathwayBrowser/#/R-CFA-177924 Dephosphorylation of Gab1 by SHP2 IEA Canis familiaris 57836 R-CFA-177926 https://reactome.org/PathwayBrowser/#/R-CFA-177926 Dephosphorylation of PAG by SHP2 IEA Canis familiaris 57836 R-CFA-177927 https://reactome.org/PathwayBrowser/#/R-CFA-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Canis familiaris 57836 R-CFA-177930 https://reactome.org/PathwayBrowser/#/R-CFA-177930 GAB1 phosphorylation by EGFR kinase IEA Canis familiaris 57836 R-CFA-177935 https://reactome.org/PathwayBrowser/#/R-CFA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Canis familiaris 57836 R-CFA-177939 https://reactome.org/PathwayBrowser/#/R-CFA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Canis familiaris 57836 R-CFA-177941 https://reactome.org/PathwayBrowser/#/R-CFA-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Canis familiaris 57836 R-CFA-177944 https://reactome.org/PathwayBrowser/#/R-CFA-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Canis familiaris 57836 R-CFA-179467 https://reactome.org/PathwayBrowser/#/R-CFA-179467 GAB1 binds phosphatidylinositol-3,4,5-trisphosphate IEA Canis familiaris 57836 R-CFA-186800 https://reactome.org/PathwayBrowser/#/R-CFA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-198266 https://reactome.org/PathwayBrowser/#/R-CFA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Canis familiaris 57836 R-CFA-199456 https://reactome.org/PathwayBrowser/#/R-CFA-199456 PTEN dephosphorylates PIP3 IEA Canis familiaris 57836 R-CFA-201510 https://reactome.org/PathwayBrowser/#/R-CFA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Canis familiaris 57836 R-CFA-202164 https://reactome.org/PathwayBrowser/#/R-CFA-202164 Translocation of PDK1 to Plasma membrane IEA Canis familiaris 57836 R-CFA-202222 https://reactome.org/PathwayBrowser/#/R-CFA-202222 Phosphorylation of PKC theta IEA Canis familiaris 57836 R-CFA-202237 https://reactome.org/PathwayBrowser/#/R-CFA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Canis familiaris 57836 R-CFA-202365 https://reactome.org/PathwayBrowser/#/R-CFA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-202394 https://reactome.org/PathwayBrowser/#/R-CFA-202394 Translocation of CARMA1 to Plasma membrane IEA Canis familiaris 57836 R-CFA-202437 https://reactome.org/PathwayBrowser/#/R-CFA-202437 Phosphorylation of CARMA1 IEA Canis familiaris 57836 R-CFA-202443 https://reactome.org/PathwayBrowser/#/R-CFA-202443 Oligomerization of CARMA1 IEA Canis familiaris 57836 R-CFA-202453 https://reactome.org/PathwayBrowser/#/R-CFA-202453 Auto-ubiquitination of TRAF6 IEA Canis familiaris 57836 R-CFA-202459 https://reactome.org/PathwayBrowser/#/R-CFA-202459 Phosphorylation of Bcl10 IEA Canis familiaris 57836 R-CFA-202466 https://reactome.org/PathwayBrowser/#/R-CFA-202466 Interaction of Bcl10 to CARMA1 IEA Canis familiaris 57836 R-CFA-202472 https://reactome.org/PathwayBrowser/#/R-CFA-202472 Translocation of TRAF6 to CBM complex IEA Canis familiaris 57836 R-CFA-202478 https://reactome.org/PathwayBrowser/#/R-CFA-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Canis familiaris 57836 R-CFA-202489 https://reactome.org/PathwayBrowser/#/R-CFA-202489 Oligomerization of Bcl10 IEA Canis familiaris 57836 R-CFA-202500 https://reactome.org/PathwayBrowser/#/R-CFA-202500 Activation of IKK complex IEA Canis familiaris 57836 R-CFA-202510 https://reactome.org/PathwayBrowser/#/R-CFA-202510 Activation of TAK1-TAB2 complex IEA Canis familiaris 57836 R-CFA-202534 https://reactome.org/PathwayBrowser/#/R-CFA-202534 Ubiquitination of NEMO by TRAF6 IEA Canis familiaris 57836 R-CFA-202692 https://reactome.org/PathwayBrowser/#/R-CFA-202692 PIP3 binds to RhoA and activates it IEA Canis familiaris 57836 R-CFA-2029268 https://reactome.org/PathwayBrowser/#/R-CFA-2029268 Phosphorylation and activation of PLCG IEA Canis familiaris 57836 R-CFA-2029271 https://reactome.org/PathwayBrowser/#/R-CFA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-2029272 https://reactome.org/PathwayBrowser/#/R-CFA-2029272 Release of PLCG from FCGR IEA Canis familiaris 57836 R-CFA-2029453 https://reactome.org/PathwayBrowser/#/R-CFA-2029453 Phosphorylation of VAV IEA Canis familiaris 57836 R-CFA-2029458 https://reactome.org/PathwayBrowser/#/R-CFA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Canis familiaris 57836 R-CFA-2029465 https://reactome.org/PathwayBrowser/#/R-CFA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Canis familiaris 57836 R-CFA-2029466 https://reactome.org/PathwayBrowser/#/R-CFA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Canis familiaris 57836 R-CFA-2029469 https://reactome.org/PathwayBrowser/#/R-CFA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Canis familiaris 57836 R-CFA-2045911 https://reactome.org/PathwayBrowser/#/R-CFA-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Canis familiaris 57836 R-CFA-2076220 https://reactome.org/PathwayBrowser/#/R-CFA-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Canis familiaris 57836 R-CFA-2130194 https://reactome.org/PathwayBrowser/#/R-CFA-2130194 ABL phosphorylates WAVEs IEA Canis familiaris 57836 R-CFA-2197690 https://reactome.org/PathwayBrowser/#/R-CFA-2197690 Detachment of WASP/WAVE IEA Canis familiaris 57836 R-CFA-2316429 https://reactome.org/PathwayBrowser/#/R-CFA-2316429 PIP3 recruits PDPK1 to the membrane IEA Canis familiaris 57836 R-CFA-2316434 https://reactome.org/PathwayBrowser/#/R-CFA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-2424476 https://reactome.org/PathwayBrowser/#/R-CFA-2424476 Activation of RAC1 by VAV2/3 IEA Canis familiaris 57836 R-CFA-2424480 https://reactome.org/PathwayBrowser/#/R-CFA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-2424481 https://reactome.org/PathwayBrowser/#/R-CFA-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Canis familiaris 57836 R-CFA-2424484 https://reactome.org/PathwayBrowser/#/R-CFA-2424484 Phosphorylation of BTK by p-SYK IEA Canis familiaris 57836 R-CFA-2424485 https://reactome.org/PathwayBrowser/#/R-CFA-2424485 Release of p-PLCG1 IEA Canis familiaris 57836 R-CFA-2424486 https://reactome.org/PathwayBrowser/#/R-CFA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Canis familiaris 57836 R-CFA-2424487 https://reactome.org/PathwayBrowser/#/R-CFA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Canis familiaris 57836 R-CFA-2730833 https://reactome.org/PathwayBrowser/#/R-CFA-2730833 Phosphorylation of TEC kinases by p-SYK IEA Canis familiaris 57836 R-CFA-2730840 https://reactome.org/PathwayBrowser/#/R-CFA-2730840 Activation of RAC1 by VAV IEA Canis familiaris 57836 R-CFA-2730841 https://reactome.org/PathwayBrowser/#/R-CFA-2730841 Phosphorylation and activation of VAV IEA Canis familiaris 57836 R-CFA-2730842 https://reactome.org/PathwayBrowser/#/R-CFA-2730842 PI3K associates with phosphorylated GAB2 IEA Canis familiaris 57836 R-CFA-2730847 https://reactome.org/PathwayBrowser/#/R-CFA-2730847 Hydrolysis of PIP2 by PLCG IEA Canis familiaris 57836 R-CFA-2730856 https://reactome.org/PathwayBrowser/#/R-CFA-2730856 Autophosphorylation of PAK IEA Canis familiaris 57836 R-CFA-2730858 https://reactome.org/PathwayBrowser/#/R-CFA-2730858 Autophosphorylation of BTK/ITK IEA Canis familiaris 57836 R-CFA-2730870 https://reactome.org/PathwayBrowser/#/R-CFA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Canis familiaris 57836 R-CFA-2730889 https://reactome.org/PathwayBrowser/#/R-CFA-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Canis familiaris 57836 R-CFA-389158 https://reactome.org/PathwayBrowser/#/R-CFA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-389348 https://reactome.org/PathwayBrowser/#/R-CFA-389348 Activation of Rac1 by pVav1 IEA Canis familiaris 57836 R-CFA-389350 https://reactome.org/PathwayBrowser/#/R-CFA-389350 Activation of Cdc42 by pVav1 IEA Canis familiaris 57836 R-CFA-389352 https://reactome.org/PathwayBrowser/#/R-CFA-389352 Translocation of Vav1 to CD28 IEA Canis familiaris 57836 R-CFA-389354 https://reactome.org/PathwayBrowser/#/R-CFA-389354 Activation of Vav1 IEA Canis familiaris 57836 R-CFA-392300 https://reactome.org/PathwayBrowser/#/R-CFA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-437162 https://reactome.org/PathwayBrowser/#/R-CFA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-442273 https://reactome.org/PathwayBrowser/#/R-CFA-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Canis familiaris 57836 R-CFA-449058 https://reactome.org/PathwayBrowser/#/R-CFA-449058 Interleukin-1 family are secreted IEA Canis familiaris 57836 R-CFA-5218819 https://reactome.org/PathwayBrowser/#/R-CFA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-5218820 https://reactome.org/PathwayBrowser/#/R-CFA-5218820 Src kinases phosphorylate VAV IEA Canis familiaris 57836 R-CFA-5218850 https://reactome.org/PathwayBrowser/#/R-CFA-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 57836 R-CFA-5357445 https://reactome.org/PathwayBrowser/#/R-CFA-5357445 PAK1-3 dimer disassociates IEA Canis familiaris 57836 R-CFA-5357472 https://reactome.org/PathwayBrowser/#/R-CFA-5357472 PAK1-3 autophosphorylates IEA Canis familiaris 57836 R-CFA-5357483 https://reactome.org/PathwayBrowser/#/R-CFA-5357483 RAC1 binds PAK1-3 IEA Canis familiaris 57836 R-CFA-5623632 https://reactome.org/PathwayBrowser/#/R-CFA-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Canis familiaris 57836 R-CFA-5623667 https://reactome.org/PathwayBrowser/#/R-CFA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Canis familiaris 57836 R-CFA-5654147 https://reactome.org/PathwayBrowser/#/R-CFA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Canis familiaris 57836 R-CFA-5654149 https://reactome.org/PathwayBrowser/#/R-CFA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Canis familiaris 57836 R-CFA-5654151 https://reactome.org/PathwayBrowser/#/R-CFA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Canis familiaris 57836 R-CFA-5654159 https://reactome.org/PathwayBrowser/#/R-CFA-5654159 Activated FGFR2 binds PLCG1 IEA Canis familiaris 57836 R-CFA-5654163 https://reactome.org/PathwayBrowser/#/R-CFA-5654163 Activated FGFR4 binds PLCG1 IEA Canis familiaris 57836 R-CFA-5654167 https://reactome.org/PathwayBrowser/#/R-CFA-5654167 Activated FGFR1 binds PLCG1 IEA Canis familiaris 57836 R-CFA-5654222 https://reactome.org/PathwayBrowser/#/R-CFA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Canis familiaris 57836 R-CFA-5654224 https://reactome.org/PathwayBrowser/#/R-CFA-5654224 Activated FGFR3 binds PLCG1 IEA Canis familiaris 57836 R-CFA-5654690 https://reactome.org/PathwayBrowser/#/R-CFA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-5654692 https://reactome.org/PathwayBrowser/#/R-CFA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-5654697 https://reactome.org/PathwayBrowser/#/R-CFA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-5654701 https://reactome.org/PathwayBrowser/#/R-CFA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-5654705 https://reactome.org/PathwayBrowser/#/R-CFA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-5654709 https://reactome.org/PathwayBrowser/#/R-CFA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-5654714 https://reactome.org/PathwayBrowser/#/R-CFA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-5654717 https://reactome.org/PathwayBrowser/#/R-CFA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-6795473 https://reactome.org/PathwayBrowser/#/R-CFA-6795473 PDPK1 phosphorylates SGK1 IEA Canis familiaris 57836 R-CFA-6805981 https://reactome.org/PathwayBrowser/#/R-CFA-6805981 HMGB1 release from cells IEA Canis familiaris 57836 R-CFA-8849969 https://reactome.org/PathwayBrowser/#/R-CFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Canis familiaris 57836 R-CFA-8852019 https://reactome.org/PathwayBrowser/#/R-CFA-8852019 MET bound PI3K generates PIP3 IEA Canis familiaris 57836 R-CFA-8874470 https://reactome.org/PathwayBrowser/#/R-CFA-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Canis familiaris 57836 R-CFA-8951586 https://reactome.org/PathwayBrowser/#/R-CFA-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Canis familiaris 57836 R-CFA-8964241 https://reactome.org/PathwayBrowser/#/R-CFA-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Canis familiaris 57836 R-CFA-8964271 https://reactome.org/PathwayBrowser/#/R-CFA-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Canis familiaris 57836 R-CFA-8964317 https://reactome.org/PathwayBrowser/#/R-CFA-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Canis familiaris 57836 R-CFA-9021627 https://reactome.org/PathwayBrowser/#/R-CFA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 57836 R-CFA-917696 https://reactome.org/PathwayBrowser/#/R-CFA-917696 Cargo Sequestration IEA Canis familiaris 57836 R-CFA-917700 https://reactome.org/PathwayBrowser/#/R-CFA-917700 MVB Vesicle Formation IEA Canis familiaris 57836 R-CFA-917730 https://reactome.org/PathwayBrowser/#/R-CFA-917730 Cargo Recognition And Sorting IEA Canis familiaris 57836 R-CFA-9606151 https://reactome.org/PathwayBrowser/#/R-CFA-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Canis familiaris 57836 R-CFA-9606884 https://reactome.org/PathwayBrowser/#/R-CFA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Canis familiaris 57836 R-CFA-9606894 https://reactome.org/PathwayBrowser/#/R-CFA-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Canis familiaris 57836 R-CFA-9632858 https://reactome.org/PathwayBrowser/#/R-CFA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Canis familiaris 57836 R-CFA-9632906 https://reactome.org/PathwayBrowser/#/R-CFA-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Canis familiaris 57836 R-CFA-9632910 https://reactome.org/PathwayBrowser/#/R-CFA-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Canis familiaris 57836 R-CFA-9632918 https://reactome.org/PathwayBrowser/#/R-CFA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Canis familiaris 57836 R-CFA-9647619 https://reactome.org/PathwayBrowser/#/R-CFA-9647619 GSDMD forms ring‐shaped oligomers IEA Canis familiaris 57836 R-CFA-9647631 https://reactome.org/PathwayBrowser/#/R-CFA-9647631 GSDMD (1-275) binds PIPs IEA Canis familiaris 57836 R-CFA-9647645 https://reactome.org/PathwayBrowser/#/R-CFA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Canis familiaris 57836 R-CFA-9647660 https://reactome.org/PathwayBrowser/#/R-CFA-9647660 GSDME (1-270) binds PIPs IEA Canis familiaris 57836 R-CFA-9691421 https://reactome.org/PathwayBrowser/#/R-CFA-9691421 BTK binds BTK inhibitors IEA Canis familiaris 57836 R-CFA-9700149 https://reactome.org/PathwayBrowser/#/R-CFA-9700149 Active ALK binds PLCG1 IEA Canis familiaris 57836 R-CFA-9700171 https://reactome.org/PathwayBrowser/#/R-CFA-9700171 Active ALK phosphorylates PLCG1 IEA Canis familiaris 57836 R-CFA-9710254 https://reactome.org/PathwayBrowser/#/R-CFA-9710254 GSDME oligomerizes IEA Canis familiaris 57836 R-DDI-109700 https://reactome.org/PathwayBrowser/#/R-DDI-109700 AKT2 binds PIP3 IEA Dictyostelium discoideum 57836 R-DDI-109701 https://reactome.org/PathwayBrowser/#/R-DDI-109701 PDPK1 binds PIP3 IEA Dictyostelium discoideum 57836 R-DDI-109702 https://reactome.org/PathwayBrowser/#/R-DDI-109702 PDPK1 phosphorylates AKT2 IEA Dictyostelium discoideum 57836 R-DDI-165162 https://reactome.org/PathwayBrowser/#/R-DDI-165162 Phosphorylation of TSC2 by PKB IEA Dictyostelium discoideum 57836 R-DDI-1675773 https://reactome.org/PathwayBrowser/#/R-DDI-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Dictyostelium discoideum 57836 R-DDI-1675949 https://reactome.org/PathwayBrowser/#/R-DDI-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Dictyostelium discoideum 57836 R-DDI-1676048 https://reactome.org/PathwayBrowser/#/R-DDI-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Dictyostelium discoideum 57836 R-DDI-198640 https://reactome.org/PathwayBrowser/#/R-DDI-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Dictyostelium discoideum 57836 R-DDI-199443 https://reactome.org/PathwayBrowser/#/R-DDI-199443 THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation IEA Dictyostelium discoideum 57836 R-DDI-199456 https://reactome.org/PathwayBrowser/#/R-DDI-199456 PTEN dephosphorylates PIP3 IEA Dictyostelium discoideum 57836 R-DDI-202164 https://reactome.org/PathwayBrowser/#/R-DDI-202164 Translocation of PDK1 to Plasma membrane IEA Dictyostelium discoideum 57836 R-DDI-202222 https://reactome.org/PathwayBrowser/#/R-DDI-202222 Phosphorylation of PKC theta IEA Dictyostelium discoideum 57836 R-DDI-2029466 https://reactome.org/PathwayBrowser/#/R-DDI-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Dictyostelium discoideum 57836 R-DDI-2029469 https://reactome.org/PathwayBrowser/#/R-DDI-2029469 p-ERK phosphorylates WAVEs and ABI IEA Dictyostelium discoideum 57836 R-DDI-2197690 https://reactome.org/PathwayBrowser/#/R-DDI-2197690 Detachment of WASP/WAVE IEA Dictyostelium discoideum 57836 R-DDI-2316429 https://reactome.org/PathwayBrowser/#/R-DDI-2316429 PIP3 recruits PDPK1 to the membrane IEA Dictyostelium discoideum 57836 R-DDI-2317314 https://reactome.org/PathwayBrowser/#/R-DDI-2317314 AKT binds PDPK1 IEA Dictyostelium discoideum 57836 R-DDI-2317332 https://reactome.org/PathwayBrowser/#/R-DDI-2317332 PIP3 recruits AKT to the membrane IEA Dictyostelium discoideum 57836 R-DDI-392300 https://reactome.org/PathwayBrowser/#/R-DDI-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Dictyostelium discoideum 57836 R-DDI-437162 https://reactome.org/PathwayBrowser/#/R-DDI-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Dictyostelium discoideum 57836 R-DDI-6795473 https://reactome.org/PathwayBrowser/#/R-DDI-6795473 PDPK1 phosphorylates SGK1 IEA Dictyostelium discoideum 57836 R-DDI-8849969 https://reactome.org/PathwayBrowser/#/R-DDI-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Dictyostelium discoideum 57836 R-DDI-917693 https://reactome.org/PathwayBrowser/#/R-DDI-917693 ESCRT Disassembly IEA Dictyostelium discoideum 57836 R-DDI-917696 https://reactome.org/PathwayBrowser/#/R-DDI-917696 Cargo Sequestration IEA Dictyostelium discoideum 57836 R-DDI-917700 https://reactome.org/PathwayBrowser/#/R-DDI-917700 MVB Vesicle Formation IEA Dictyostelium discoideum 57836 R-DDI-9603279 https://reactome.org/PathwayBrowser/#/R-DDI-9603279 PIP3 recruits PDK1 and AKT to the membrane IEA Dictyostelium discoideum 57836 R-DDI-9606884 https://reactome.org/PathwayBrowser/#/R-DDI-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Dictyostelium discoideum 57836 R-DDI-9606894 https://reactome.org/PathwayBrowser/#/R-DDI-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Dictyostelium discoideum 57836 R-DDI-9632858 https://reactome.org/PathwayBrowser/#/R-DDI-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Dictyostelium discoideum 57836 R-DME-109699 https://reactome.org/PathwayBrowser/#/R-DME-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-109700 https://reactome.org/PathwayBrowser/#/R-DME-109700 AKT2 binds PIP3 IEA Drosophila melanogaster 57836 R-DME-109701 https://reactome.org/PathwayBrowser/#/R-DME-109701 PDPK1 binds PIP3 IEA Drosophila melanogaster 57836 R-DME-109702 https://reactome.org/PathwayBrowser/#/R-DME-109702 PDPK1 phosphorylates AKT2 IEA Drosophila melanogaster 57836 R-DME-110453 https://reactome.org/PathwayBrowser/#/R-DME-110453 Phosphorylation of PIP2 to PIP3 by Dp110 TAS Drosophila melanogaster 57836 R-DME-110459 https://reactome.org/PathwayBrowser/#/R-DME-110459 PIP3 dephosphorylated to PIP2 by DPTEN TAS Drosophila melanogaster 57836 R-DME-110463 https://reactome.org/PathwayBrowser/#/R-DME-110463 Increased PIP3 levels recruit DAkt1 to the membrane TAS Drosophila melanogaster 57836 R-DME-110468 https://reactome.org/PathwayBrowser/#/R-DME-110468 Activation of DAkt1 by DPDK1 TAS Drosophila melanogaster 57836 R-DME-1250370 https://reactome.org/PathwayBrowser/#/R-DME-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Drosophila melanogaster 57836 R-DME-1250462 https://reactome.org/PathwayBrowser/#/R-DME-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Drosophila melanogaster 57836 R-DME-1306957 https://reactome.org/PathwayBrowser/#/R-DME-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Drosophila melanogaster 57836 R-DME-1306979 https://reactome.org/PathwayBrowser/#/R-DME-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Drosophila melanogaster 57836 R-DME-1433415 https://reactome.org/PathwayBrowser/#/R-DME-1433415 Activation of RAC1 IEA Drosophila melanogaster 57836 R-DME-165162 https://reactome.org/PathwayBrowser/#/R-DME-165162 Phosphorylation of TSC2 by PKB IEA Drosophila melanogaster 57836 R-DME-165182 https://reactome.org/PathwayBrowser/#/R-DME-165182 Phosphorylation of complexed TSC2 by PKB IEA Drosophila melanogaster 57836 R-DME-1675773 https://reactome.org/PathwayBrowser/#/R-DME-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Drosophila melanogaster 57836 R-DME-1675949 https://reactome.org/PathwayBrowser/#/R-DME-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Drosophila melanogaster 57836 R-DME-1676048 https://reactome.org/PathwayBrowser/#/R-DME-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Drosophila melanogaster 57836 R-DME-177923 https://reactome.org/PathwayBrowser/#/R-DME-177923 Sustained activation of SRC kinase by SHP2 IEA Drosophila melanogaster 57836 R-DME-177924 https://reactome.org/PathwayBrowser/#/R-DME-177924 Dephosphorylation of Gab1 by SHP2 IEA Drosophila melanogaster 57836 R-DME-177930 https://reactome.org/PathwayBrowser/#/R-DME-177930 GAB1 phosphorylation by EGFR kinase IEA Drosophila melanogaster 57836 R-DME-177935 https://reactome.org/PathwayBrowser/#/R-DME-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Drosophila melanogaster 57836 R-DME-177939 https://reactome.org/PathwayBrowser/#/R-DME-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Drosophila melanogaster 57836 R-DME-177941 https://reactome.org/PathwayBrowser/#/R-DME-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Drosophila melanogaster 57836 R-DME-179467 https://reactome.org/PathwayBrowser/#/R-DME-179467 GAB1 binds phosphatidylinositol-3,4,5-trisphosphate IEA Drosophila melanogaster 57836 R-DME-186800 https://reactome.org/PathwayBrowser/#/R-DME-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-198266 https://reactome.org/PathwayBrowser/#/R-DME-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Drosophila melanogaster 57836 R-DME-198640 https://reactome.org/PathwayBrowser/#/R-DME-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Drosophila melanogaster 57836 R-DME-199443 https://reactome.org/PathwayBrowser/#/R-DME-199443 THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation IEA Drosophila melanogaster 57836 R-DME-199456 https://reactome.org/PathwayBrowser/#/R-DME-199456 PTEN dephosphorylates PIP3 IEA Drosophila melanogaster 57836 R-DME-201510 https://reactome.org/PathwayBrowser/#/R-DME-201510 PI3K synthesizes PIP3 downstream of ALK IEA Drosophila melanogaster 57836 R-DME-202164 https://reactome.org/PathwayBrowser/#/R-DME-202164 Translocation of PDK1 to Plasma membrane IEA Drosophila melanogaster 57836 R-DME-202222 https://reactome.org/PathwayBrowser/#/R-DME-202222 Phosphorylation of PKC theta IEA Drosophila melanogaster 57836 R-DME-202692 https://reactome.org/PathwayBrowser/#/R-DME-202692 PIP3 binds to RhoA and activates it IEA Drosophila melanogaster 57836 R-DME-2029465 https://reactome.org/PathwayBrowser/#/R-DME-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Drosophila melanogaster 57836 R-DME-2029466 https://reactome.org/PathwayBrowser/#/R-DME-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Drosophila melanogaster 57836 R-DME-2029469 https://reactome.org/PathwayBrowser/#/R-DME-2029469 p-ERK phosphorylates WAVEs and ABI IEA Drosophila melanogaster 57836 R-DME-2045911 https://reactome.org/PathwayBrowser/#/R-DME-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Drosophila melanogaster 57836 R-DME-2076220 https://reactome.org/PathwayBrowser/#/R-DME-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Drosophila melanogaster 57836 R-DME-2130194 https://reactome.org/PathwayBrowser/#/R-DME-2130194 ABL phosphorylates WAVEs IEA Drosophila melanogaster 57836 R-DME-2197690 https://reactome.org/PathwayBrowser/#/R-DME-2197690 Detachment of WASP/WAVE IEA Drosophila melanogaster 57836 R-DME-2316429 https://reactome.org/PathwayBrowser/#/R-DME-2316429 PIP3 recruits PDPK1 to the membrane IEA Drosophila melanogaster 57836 R-DME-2316434 https://reactome.org/PathwayBrowser/#/R-DME-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-2317314 https://reactome.org/PathwayBrowser/#/R-DME-2317314 AKT binds PDPK1 IEA Drosophila melanogaster 57836 R-DME-2317332 https://reactome.org/PathwayBrowser/#/R-DME-2317332 PIP3 recruits AKT to the membrane IEA Drosophila melanogaster 57836 R-DME-2424476 https://reactome.org/PathwayBrowser/#/R-DME-2424476 Activation of RAC1 by VAV2/3 IEA Drosophila melanogaster 57836 R-DME-2424481 https://reactome.org/PathwayBrowser/#/R-DME-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Drosophila melanogaster 57836 R-DME-2424485 https://reactome.org/PathwayBrowser/#/R-DME-2424485 Release of p-PLCG1 IEA Drosophila melanogaster 57836 R-DME-2424487 https://reactome.org/PathwayBrowser/#/R-DME-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Drosophila melanogaster 57836 R-DME-2730840 https://reactome.org/PathwayBrowser/#/R-DME-2730840 Activation of RAC1 by VAV IEA Drosophila melanogaster 57836 R-DME-2730841 https://reactome.org/PathwayBrowser/#/R-DME-2730841 Phosphorylation and activation of VAV IEA Drosophila melanogaster 57836 R-DME-2730842 https://reactome.org/PathwayBrowser/#/R-DME-2730842 PI3K associates with phosphorylated GAB2 IEA Drosophila melanogaster 57836 R-DME-2730847 https://reactome.org/PathwayBrowser/#/R-DME-2730847 Hydrolysis of PIP2 by PLCG IEA Drosophila melanogaster 57836 R-DME-2730856 https://reactome.org/PathwayBrowser/#/R-DME-2730856 Autophosphorylation of PAK IEA Drosophila melanogaster 57836 R-DME-2730858 https://reactome.org/PathwayBrowser/#/R-DME-2730858 Autophosphorylation of BTK/ITK IEA Drosophila melanogaster 57836 R-DME-2730870 https://reactome.org/PathwayBrowser/#/R-DME-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Drosophila melanogaster 57836 R-DME-2730889 https://reactome.org/PathwayBrowser/#/R-DME-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Drosophila melanogaster 57836 R-DME-392300 https://reactome.org/PathwayBrowser/#/R-DME-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-437162 https://reactome.org/PathwayBrowser/#/R-DME-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-442273 https://reactome.org/PathwayBrowser/#/R-DME-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Drosophila melanogaster 57836 R-DME-5218819 https://reactome.org/PathwayBrowser/#/R-DME-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-5218850 https://reactome.org/PathwayBrowser/#/R-DME-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 57836 R-DME-5357445 https://reactome.org/PathwayBrowser/#/R-DME-5357445 PAK1-3 dimer disassociates IEA Drosophila melanogaster 57836 R-DME-5357472 https://reactome.org/PathwayBrowser/#/R-DME-5357472 PAK1-3 autophosphorylates IEA Drosophila melanogaster 57836 R-DME-5357483 https://reactome.org/PathwayBrowser/#/R-DME-5357483 RAC1 binds PAK1-3 IEA Drosophila melanogaster 57836 R-DME-5623632 https://reactome.org/PathwayBrowser/#/R-DME-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Drosophila melanogaster 57836 R-DME-5623667 https://reactome.org/PathwayBrowser/#/R-DME-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Drosophila melanogaster 57836 R-DME-5654147 https://reactome.org/PathwayBrowser/#/R-DME-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Drosophila melanogaster 57836 R-DME-5654149 https://reactome.org/PathwayBrowser/#/R-DME-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Drosophila melanogaster 57836 R-DME-5654151 https://reactome.org/PathwayBrowser/#/R-DME-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Drosophila melanogaster 57836 R-DME-5654159 https://reactome.org/PathwayBrowser/#/R-DME-5654159 Activated FGFR2 binds PLCG1 IEA Drosophila melanogaster 57836 R-DME-5654163 https://reactome.org/PathwayBrowser/#/R-DME-5654163 Activated FGFR4 binds PLCG1 IEA Drosophila melanogaster 57836 R-DME-5654167 https://reactome.org/PathwayBrowser/#/R-DME-5654167 Activated FGFR1 binds PLCG1 IEA Drosophila melanogaster 57836 R-DME-5654222 https://reactome.org/PathwayBrowser/#/R-DME-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Drosophila melanogaster 57836 R-DME-5654224 https://reactome.org/PathwayBrowser/#/R-DME-5654224 Activated FGFR3 binds PLCG1 IEA Drosophila melanogaster 57836 R-DME-5654690 https://reactome.org/PathwayBrowser/#/R-DME-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-5654692 https://reactome.org/PathwayBrowser/#/R-DME-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-5654697 https://reactome.org/PathwayBrowser/#/R-DME-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-5654701 https://reactome.org/PathwayBrowser/#/R-DME-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-5654705 https://reactome.org/PathwayBrowser/#/R-DME-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-5654709 https://reactome.org/PathwayBrowser/#/R-DME-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-5654714 https://reactome.org/PathwayBrowser/#/R-DME-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-5654717 https://reactome.org/PathwayBrowser/#/R-DME-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-8849969 https://reactome.org/PathwayBrowser/#/R-DME-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Drosophila melanogaster 57836 R-DME-8874470 https://reactome.org/PathwayBrowser/#/R-DME-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Drosophila melanogaster 57836 R-DME-8951586 https://reactome.org/PathwayBrowser/#/R-DME-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Drosophila melanogaster 57836 R-DME-8964241 https://reactome.org/PathwayBrowser/#/R-DME-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Drosophila melanogaster 57836 R-DME-8964271 https://reactome.org/PathwayBrowser/#/R-DME-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Drosophila melanogaster 57836 R-DME-8964317 https://reactome.org/PathwayBrowser/#/R-DME-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Drosophila melanogaster 57836 R-DME-9021627 https://reactome.org/PathwayBrowser/#/R-DME-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 57836 R-DME-917693 https://reactome.org/PathwayBrowser/#/R-DME-917693 ESCRT Disassembly IEA Drosophila melanogaster 57836 R-DME-917696 https://reactome.org/PathwayBrowser/#/R-DME-917696 Cargo Sequestration IEA Drosophila melanogaster 57836 R-DME-917700 https://reactome.org/PathwayBrowser/#/R-DME-917700 MVB Vesicle Formation IEA Drosophila melanogaster 57836 R-DME-917730 https://reactome.org/PathwayBrowser/#/R-DME-917730 Cargo Recognition And Sorting IEA Drosophila melanogaster 57836 R-DME-9603279 https://reactome.org/PathwayBrowser/#/R-DME-9603279 PIP3 recruits PDK1 and AKT to the membrane IEA Drosophila melanogaster 57836 R-DME-9632858 https://reactome.org/PathwayBrowser/#/R-DME-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Drosophila melanogaster 57836 R-DME-9632906 https://reactome.org/PathwayBrowser/#/R-DME-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Drosophila melanogaster 57836 R-DME-9632910 https://reactome.org/PathwayBrowser/#/R-DME-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Drosophila melanogaster 57836 R-DME-9632918 https://reactome.org/PathwayBrowser/#/R-DME-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Drosophila melanogaster 57836 R-DRE-109700 https://reactome.org/PathwayBrowser/#/R-DRE-109700 AKT2 binds PIP3 IEA Danio rerio 57836 R-DRE-109701 https://reactome.org/PathwayBrowser/#/R-DRE-109701 PDPK1 binds PIP3 IEA Danio rerio 57836 R-DRE-109702 https://reactome.org/PathwayBrowser/#/R-DRE-109702 PDPK1 phosphorylates AKT2 IEA Danio rerio 57836 R-DRE-1250370 https://reactome.org/PathwayBrowser/#/R-DRE-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Danio rerio 57836 R-DRE-1250462 https://reactome.org/PathwayBrowser/#/R-DRE-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Danio rerio 57836 R-DRE-1306979 https://reactome.org/PathwayBrowser/#/R-DRE-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Danio rerio 57836 R-DRE-1433514 https://reactome.org/PathwayBrowser/#/R-DRE-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Danio rerio 57836 R-DRE-1675773 https://reactome.org/PathwayBrowser/#/R-DRE-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Danio rerio 57836 R-DRE-1675949 https://reactome.org/PathwayBrowser/#/R-DRE-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Danio rerio 57836 R-DRE-1676048 https://reactome.org/PathwayBrowser/#/R-DRE-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Danio rerio 57836 R-DRE-177939 https://reactome.org/PathwayBrowser/#/R-DRE-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Danio rerio 57836 R-DRE-186800 https://reactome.org/PathwayBrowser/#/R-DRE-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Danio rerio 57836 R-DRE-199443 https://reactome.org/PathwayBrowser/#/R-DRE-199443 THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation IEA Danio rerio 57836 R-DRE-199456 https://reactome.org/PathwayBrowser/#/R-DRE-199456 PTEN dephosphorylates PIP3 IEA Danio rerio 57836 R-DRE-201510 https://reactome.org/PathwayBrowser/#/R-DRE-201510 PI3K synthesizes PIP3 downstream of ALK IEA Danio rerio 57836 R-DRE-202164 https://reactome.org/PathwayBrowser/#/R-DRE-202164 Translocation of PDK1 to Plasma membrane IEA Danio rerio 57836 R-DRE-202692 https://reactome.org/PathwayBrowser/#/R-DRE-202692 PIP3 binds to RhoA and activates it IEA Danio rerio 57836 R-DRE-2045911 https://reactome.org/PathwayBrowser/#/R-DRE-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Danio rerio 57836 R-DRE-2316429 https://reactome.org/PathwayBrowser/#/R-DRE-2316429 PIP3 recruits PDPK1 to the membrane IEA Danio rerio 57836 R-DRE-2316434 https://reactome.org/PathwayBrowser/#/R-DRE-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 57836 R-DRE-2317314 https://reactome.org/PathwayBrowser/#/R-DRE-2317314 AKT binds PDPK1 IEA Danio rerio 57836 R-DRE-2317332 https://reactome.org/PathwayBrowser/#/R-DRE-2317332 PIP3 recruits AKT to the membrane IEA Danio rerio 57836 R-DRE-437162 https://reactome.org/PathwayBrowser/#/R-DRE-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Danio rerio 57836 R-DRE-5218819 https://reactome.org/PathwayBrowser/#/R-DRE-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 57836 R-DRE-5623632 https://reactome.org/PathwayBrowser/#/R-DRE-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Danio rerio 57836 R-DRE-5623667 https://reactome.org/PathwayBrowser/#/R-DRE-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Danio rerio 57836 R-DRE-5654147 https://reactome.org/PathwayBrowser/#/R-DRE-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Danio rerio 57836 R-DRE-5654149 https://reactome.org/PathwayBrowser/#/R-DRE-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Danio rerio 57836 R-DRE-5654151 https://reactome.org/PathwayBrowser/#/R-DRE-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Danio rerio 57836 R-DRE-5654159 https://reactome.org/PathwayBrowser/#/R-DRE-5654159 Activated FGFR2 binds PLCG1 IEA Danio rerio 57836 R-DRE-5654163 https://reactome.org/PathwayBrowser/#/R-DRE-5654163 Activated FGFR4 binds PLCG1 IEA Danio rerio 57836 R-DRE-5654167 https://reactome.org/PathwayBrowser/#/R-DRE-5654167 Activated FGFR1 binds PLCG1 IEA Danio rerio 57836 R-DRE-5654222 https://reactome.org/PathwayBrowser/#/R-DRE-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Danio rerio 57836 R-DRE-5654224 https://reactome.org/PathwayBrowser/#/R-DRE-5654224 Activated FGFR3 binds PLCG1 IEA Danio rerio 57836 R-DRE-5654690 https://reactome.org/PathwayBrowser/#/R-DRE-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 57836 R-DRE-6795473 https://reactome.org/PathwayBrowser/#/R-DRE-6795473 PDPK1 phosphorylates SGK1 IEA Danio rerio 57836 R-DRE-6805981 https://reactome.org/PathwayBrowser/#/R-DRE-6805981 HMGB1 release from cells IEA Danio rerio 57836 R-DRE-8849969 https://reactome.org/PathwayBrowser/#/R-DRE-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Danio rerio 57836 R-DRE-8874470 https://reactome.org/PathwayBrowser/#/R-DRE-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Danio rerio 57836 R-DRE-917696 https://reactome.org/PathwayBrowser/#/R-DRE-917696 Cargo Sequestration IEA Danio rerio 57836 R-DRE-917700 https://reactome.org/PathwayBrowser/#/R-DRE-917700 MVB Vesicle Formation IEA Danio rerio 57836 R-DRE-9603279 https://reactome.org/PathwayBrowser/#/R-DRE-9603279 PIP3 recruits PDK1 and AKT to the membrane IEA Danio rerio 57836 R-DRE-9606884 https://reactome.org/PathwayBrowser/#/R-DRE-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Danio rerio 57836 R-DRE-9647660 https://reactome.org/PathwayBrowser/#/R-DRE-9647660 GSDME (1-270) binds PIPs IEA Danio rerio 57836 R-DRE-9700149 https://reactome.org/PathwayBrowser/#/R-DRE-9700149 Active ALK binds PLCG1 IEA Danio rerio 57836 R-DRE-9700171 https://reactome.org/PathwayBrowser/#/R-DRE-9700171 Active ALK phosphorylates PLCG1 IEA Danio rerio 57836 R-DRE-9710254 https://reactome.org/PathwayBrowser/#/R-DRE-9710254 GSDME oligomerizes IEA Danio rerio 57836 R-GGA-109699 https://reactome.org/PathwayBrowser/#/R-GGA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-109701 https://reactome.org/PathwayBrowser/#/R-GGA-109701 PDPK1 binds PIP3 IEA Gallus gallus 57836 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus 57836 R-GGA-1250370 https://reactome.org/PathwayBrowser/#/R-GGA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Gallus gallus 57836 R-GGA-1250462 https://reactome.org/PathwayBrowser/#/R-GGA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Gallus gallus 57836 R-GGA-1306957 https://reactome.org/PathwayBrowser/#/R-GGA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus 57836 R-GGA-1306979 https://reactome.org/PathwayBrowser/#/R-GGA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Gallus gallus 57836 R-GGA-1433514 https://reactome.org/PathwayBrowser/#/R-GGA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Gallus gallus 57836 R-GGA-1675773 https://reactome.org/PathwayBrowser/#/R-GGA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Gallus gallus 57836 R-GGA-1675949 https://reactome.org/PathwayBrowser/#/R-GGA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Gallus gallus 57836 R-GGA-1676048 https://reactome.org/PathwayBrowser/#/R-GGA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Gallus gallus 57836 R-GGA-177923 https://reactome.org/PathwayBrowser/#/R-GGA-177923 Sustained activation of SRC kinase by SHP2 IEA Gallus gallus 57836 R-GGA-177924 https://reactome.org/PathwayBrowser/#/R-GGA-177924 Dephosphorylation of Gab1 by SHP2 IEA Gallus gallus 57836 R-GGA-177926 https://reactome.org/PathwayBrowser/#/R-GGA-177926 Dephosphorylation of PAG by SHP2 IEA Gallus gallus 57836 R-GGA-177927 https://reactome.org/PathwayBrowser/#/R-GGA-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Gallus gallus 57836 R-GGA-177930 https://reactome.org/PathwayBrowser/#/R-GGA-177930 GAB1 phosphorylation by EGFR kinase IEA Gallus gallus 57836 R-GGA-177935 https://reactome.org/PathwayBrowser/#/R-GGA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Gallus gallus 57836 R-GGA-177939 https://reactome.org/PathwayBrowser/#/R-GGA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Gallus gallus 57836 R-GGA-177941 https://reactome.org/PathwayBrowser/#/R-GGA-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Gallus gallus 57836 R-GGA-177944 https://reactome.org/PathwayBrowser/#/R-GGA-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Gallus gallus 57836 R-GGA-179467 https://reactome.org/PathwayBrowser/#/R-GGA-179467 GAB1 binds phosphatidylinositol-3,4,5-trisphosphate IEA Gallus gallus 57836 R-GGA-186800 https://reactome.org/PathwayBrowser/#/R-GGA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-198266 https://reactome.org/PathwayBrowser/#/R-GGA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Gallus gallus 57836 R-GGA-198640 https://reactome.org/PathwayBrowser/#/R-GGA-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Gallus gallus 57836 R-GGA-199443 https://reactome.org/PathwayBrowser/#/R-GGA-199443 THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation IEA Gallus gallus 57836 R-GGA-199456 https://reactome.org/PathwayBrowser/#/R-GGA-199456 PTEN dephosphorylates PIP3 IEA Gallus gallus 57836 R-GGA-201510 https://reactome.org/PathwayBrowser/#/R-GGA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Gallus gallus 57836 R-GGA-202164 https://reactome.org/PathwayBrowser/#/R-GGA-202164 Translocation of PDK1 to Plasma membrane IEA Gallus gallus 57836 R-GGA-202237 https://reactome.org/PathwayBrowser/#/R-GGA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Gallus gallus 57836 R-GGA-202365 https://reactome.org/PathwayBrowser/#/R-GGA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-202394 https://reactome.org/PathwayBrowser/#/R-GGA-202394 Translocation of CARMA1 to Plasma membrane IEA Gallus gallus 57836 R-GGA-202443 https://reactome.org/PathwayBrowser/#/R-GGA-202443 Oligomerization of CARMA1 IEA Gallus gallus 57836 R-GGA-202459 https://reactome.org/PathwayBrowser/#/R-GGA-202459 Phosphorylation of Bcl10 IEA Gallus gallus 57836 R-GGA-202466 https://reactome.org/PathwayBrowser/#/R-GGA-202466 Interaction of Bcl10 to CARMA1 IEA Gallus gallus 57836 R-GGA-202472 https://reactome.org/PathwayBrowser/#/R-GGA-202472 Translocation of TRAF6 to CBM complex IEA Gallus gallus 57836 R-GGA-202478 https://reactome.org/PathwayBrowser/#/R-GGA-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Gallus gallus 57836 R-GGA-202489 https://reactome.org/PathwayBrowser/#/R-GGA-202489 Oligomerization of Bcl10 IEA Gallus gallus 57836 R-GGA-202510 https://reactome.org/PathwayBrowser/#/R-GGA-202510 Activation of TAK1-TAB2 complex IEA Gallus gallus 57836 R-GGA-202692 https://reactome.org/PathwayBrowser/#/R-GGA-202692 PIP3 binds to RhoA and activates it IEA Gallus gallus 57836 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus 57836 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-2029272 https://reactome.org/PathwayBrowser/#/R-GGA-2029272 Release of PLCG from FCGR IEA Gallus gallus 57836 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus 57836 R-GGA-2029458 https://reactome.org/PathwayBrowser/#/R-GGA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Gallus gallus 57836 R-GGA-2029465 https://reactome.org/PathwayBrowser/#/R-GGA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Gallus gallus 57836 R-GGA-2029466 https://reactome.org/PathwayBrowser/#/R-GGA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Gallus gallus 57836 R-GGA-2029469 https://reactome.org/PathwayBrowser/#/R-GGA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Gallus gallus 57836 R-GGA-2045911 https://reactome.org/PathwayBrowser/#/R-GGA-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Gallus gallus 57836 R-GGA-2130194 https://reactome.org/PathwayBrowser/#/R-GGA-2130194 ABL phosphorylates WAVEs IEA Gallus gallus 57836 R-GGA-2197690 https://reactome.org/PathwayBrowser/#/R-GGA-2197690 Detachment of WASP/WAVE IEA Gallus gallus 57836 R-GGA-2316429 https://reactome.org/PathwayBrowser/#/R-GGA-2316429 PIP3 recruits PDPK1 to the membrane IEA Gallus gallus 57836 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-2317314 https://reactome.org/PathwayBrowser/#/R-GGA-2317314 AKT binds PDPK1 IEA Gallus gallus 57836 R-GGA-2317332 https://reactome.org/PathwayBrowser/#/R-GGA-2317332 PIP3 recruits AKT to the membrane IEA Gallus gallus 57836 R-GGA-2424476 https://reactome.org/PathwayBrowser/#/R-GGA-2424476 Activation of RAC1 by VAV2/3 IEA Gallus gallus 57836 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-2424481 https://reactome.org/PathwayBrowser/#/R-GGA-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Gallus gallus 57836 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus 57836 R-GGA-2424485 https://reactome.org/PathwayBrowser/#/R-GGA-2424485 Release of p-PLCG1 IEA Gallus gallus 57836 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus 57836 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus 57836 R-GGA-2730840 https://reactome.org/PathwayBrowser/#/R-GGA-2730840 Activation of RAC1 by VAV IEA Gallus gallus 57836 R-GGA-2730841 https://reactome.org/PathwayBrowser/#/R-GGA-2730841 Phosphorylation and activation of VAV IEA Gallus gallus 57836 R-GGA-2730842 https://reactome.org/PathwayBrowser/#/R-GGA-2730842 PI3K associates with phosphorylated GAB2 IEA Gallus gallus 57836 R-GGA-2730847 https://reactome.org/PathwayBrowser/#/R-GGA-2730847 Hydrolysis of PIP2 by PLCG IEA Gallus gallus 57836 R-GGA-2730856 https://reactome.org/PathwayBrowser/#/R-GGA-2730856 Autophosphorylation of PAK IEA Gallus gallus 57836 R-GGA-2730858 https://reactome.org/PathwayBrowser/#/R-GGA-2730858 Autophosphorylation of BTK/ITK IEA Gallus gallus 57836 R-GGA-2730870 https://reactome.org/PathwayBrowser/#/R-GGA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Gallus gallus 57836 R-GGA-2730889 https://reactome.org/PathwayBrowser/#/R-GGA-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Gallus gallus 57836 R-GGA-389158 https://reactome.org/PathwayBrowser/#/R-GGA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-389348 https://reactome.org/PathwayBrowser/#/R-GGA-389348 Activation of Rac1 by pVav1 IEA Gallus gallus 57836 R-GGA-389350 https://reactome.org/PathwayBrowser/#/R-GGA-389350 Activation of Cdc42 by pVav1 IEA Gallus gallus 57836 R-GGA-389354 https://reactome.org/PathwayBrowser/#/R-GGA-389354 Activation of Vav1 IEA Gallus gallus 57836 R-GGA-392300 https://reactome.org/PathwayBrowser/#/R-GGA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-437162 https://reactome.org/PathwayBrowser/#/R-GGA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-449058 https://reactome.org/PathwayBrowser/#/R-GGA-449058 Interleukin-1 family are secreted IEA Gallus gallus 57836 R-GGA-5218819 https://reactome.org/PathwayBrowser/#/R-GGA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-5218820 https://reactome.org/PathwayBrowser/#/R-GGA-5218820 Src kinases phosphorylate VAV IEA Gallus gallus 57836 R-GGA-5218850 https://reactome.org/PathwayBrowser/#/R-GGA-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 57836 R-GGA-5357445 https://reactome.org/PathwayBrowser/#/R-GGA-5357445 PAK1-3 dimer disassociates IEA Gallus gallus 57836 R-GGA-5357472 https://reactome.org/PathwayBrowser/#/R-GGA-5357472 PAK1-3 autophosphorylates IEA Gallus gallus 57836 R-GGA-5357483 https://reactome.org/PathwayBrowser/#/R-GGA-5357483 RAC1 binds PAK1-3 IEA Gallus gallus 57836 R-GGA-5623632 https://reactome.org/PathwayBrowser/#/R-GGA-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Gallus gallus 57836 R-GGA-5623667 https://reactome.org/PathwayBrowser/#/R-GGA-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Gallus gallus 57836 R-GGA-5654147 https://reactome.org/PathwayBrowser/#/R-GGA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Gallus gallus 57836 R-GGA-5654149 https://reactome.org/PathwayBrowser/#/R-GGA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Gallus gallus 57836 R-GGA-5654151 https://reactome.org/PathwayBrowser/#/R-GGA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Gallus gallus 57836 R-GGA-5654159 https://reactome.org/PathwayBrowser/#/R-GGA-5654159 Activated FGFR2 binds PLCG1 IEA Gallus gallus 57836 R-GGA-5654163 https://reactome.org/PathwayBrowser/#/R-GGA-5654163 Activated FGFR4 binds PLCG1 IEA Gallus gallus 57836 R-GGA-5654167 https://reactome.org/PathwayBrowser/#/R-GGA-5654167 Activated FGFR1 binds PLCG1 IEA Gallus gallus 57836 R-GGA-5654222 https://reactome.org/PathwayBrowser/#/R-GGA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Gallus gallus 57836 R-GGA-5654224 https://reactome.org/PathwayBrowser/#/R-GGA-5654224 Activated FGFR3 binds PLCG1 IEA Gallus gallus 57836 R-GGA-5654690 https://reactome.org/PathwayBrowser/#/R-GGA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-5654692 https://reactome.org/PathwayBrowser/#/R-GGA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-5654697 https://reactome.org/PathwayBrowser/#/R-GGA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-5654701 https://reactome.org/PathwayBrowser/#/R-GGA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-5654705 https://reactome.org/PathwayBrowser/#/R-GGA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-5654709 https://reactome.org/PathwayBrowser/#/R-GGA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-5654714 https://reactome.org/PathwayBrowser/#/R-GGA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-5654717 https://reactome.org/PathwayBrowser/#/R-GGA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 57836 R-GGA-6795473 https://reactome.org/PathwayBrowser/#/R-GGA-6795473 PDPK1 phosphorylates SGK1 IEA Gallus gallus 57836 R-GGA-6805981 https://reactome.org/PathwayBrowser/#/R-GGA-6805981 HMGB1 release from cells IEA Gallus gallus 57836 R-GGA-8849969 https://reactome.org/PathwayBrowser/#/R-GGA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Gallus gallus 57836 R-GGA-8852019 https://reactome.org/PathwayBrowser/#/R-GGA-8852019 MET bound PI3K generates PIP3 IEA Gallus gallus 57836 R-GGA-8874470 https://reactome.org/PathwayBrowser/#/R-GGA-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Gallus gallus 57836 R-GGA-8951586 https://reactome.org/PathwayBrowser/#/R-GGA-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Gallus gallus 57836 R-GGA-8964241 https://reactome.org/PathwayBrowser/#/R-GGA-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Gallus gallus 57836 R-GGA-8964271 https://reactome.org/PathwayBrowser/#/R-GGA-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Gallus gallus 57836 R-GGA-8964317 https://reactome.org/PathwayBrowser/#/R-GGA-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Gallus gallus 57836 R-GGA-917693 https://reactome.org/PathwayBrowser/#/R-GGA-917693 ESCRT Disassembly IEA Gallus gallus 57836 R-GGA-917696 https://reactome.org/PathwayBrowser/#/R-GGA-917696 Cargo Sequestration IEA Gallus gallus 57836 R-GGA-917700 https://reactome.org/PathwayBrowser/#/R-GGA-917700 MVB Vesicle Formation IEA Gallus gallus 57836 R-GGA-917730 https://reactome.org/PathwayBrowser/#/R-GGA-917730 Cargo Recognition And Sorting IEA Gallus gallus 57836 R-GGA-9603279 https://reactome.org/PathwayBrowser/#/R-GGA-9603279 PIP3 recruits PDK1 and AKT to the membrane IEA Gallus gallus 57836 R-GGA-9606884 https://reactome.org/PathwayBrowser/#/R-GGA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Gallus gallus 57836 R-GGA-9606894 https://reactome.org/PathwayBrowser/#/R-GGA-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Gallus gallus 57836 R-GGA-9632858 https://reactome.org/PathwayBrowser/#/R-GGA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Gallus gallus 57836 R-GGA-9632906 https://reactome.org/PathwayBrowser/#/R-GGA-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Gallus gallus 57836 R-GGA-9632910 https://reactome.org/PathwayBrowser/#/R-GGA-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Gallus gallus 57836 R-GGA-9632918 https://reactome.org/PathwayBrowser/#/R-GGA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Gallus gallus 57836 R-GGA-9647619 https://reactome.org/PathwayBrowser/#/R-GGA-9647619 GSDMD forms ring‐shaped oligomers IEA Gallus gallus 57836 R-GGA-9647631 https://reactome.org/PathwayBrowser/#/R-GGA-9647631 GSDMD (1-275) binds PIPs IEA Gallus gallus 57836 R-GGA-9647645 https://reactome.org/PathwayBrowser/#/R-GGA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Gallus gallus 57836 R-GGA-9647660 https://reactome.org/PathwayBrowser/#/R-GGA-9647660 GSDME (1-270) binds PIPs IEA Gallus gallus 57836 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus 57836 R-GGA-9700149 https://reactome.org/PathwayBrowser/#/R-GGA-9700149 Active ALK binds PLCG1 IEA Gallus gallus 57836 R-GGA-9700171 https://reactome.org/PathwayBrowser/#/R-GGA-9700171 Active ALK phosphorylates PLCG1 IEA Gallus gallus 57836 R-GGA-9710254 https://reactome.org/PathwayBrowser/#/R-GGA-9710254 GSDME oligomerizes IEA Gallus gallus 57836 R-HSA-109699 https://reactome.org/PathwayBrowser/#/R-HSA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-109700 https://reactome.org/PathwayBrowser/#/R-HSA-109700 AKT2 binds PIP3 TAS Homo sapiens 57836 R-HSA-109701 https://reactome.org/PathwayBrowser/#/R-HSA-109701 PDPK1 binds PIP3 TAS Homo sapiens 57836 R-HSA-109702 https://reactome.org/PathwayBrowser/#/R-HSA-109702 PDPK1 phosphorylates AKT2 TAS Homo sapiens 57836 R-HSA-1112666 https://reactome.org/PathwayBrowser/#/R-HSA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate TAS Homo sapiens 57836 R-HSA-1226014 https://reactome.org/PathwayBrowser/#/R-HSA-1226014 Conversion of PIP2 to PIP3 by PI3K bound to ligand-responsive p-6Y-EGFR mutants TAS Homo sapiens 57836 R-HSA-1250370 https://reactome.org/PathwayBrowser/#/R-HSA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers TAS Homo sapiens 57836 R-HSA-1250462 https://reactome.org/PathwayBrowser/#/R-HSA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 TAS Homo sapiens 57836 R-HSA-1306957 https://reactome.org/PathwayBrowser/#/R-HSA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR TAS Homo sapiens 57836 R-HSA-1306979 https://reactome.org/PathwayBrowser/#/R-HSA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 TAS Homo sapiens 57836 R-HSA-1433415 https://reactome.org/PathwayBrowser/#/R-HSA-1433415 Activation of RAC1 TAS Homo sapiens 57836 R-HSA-1433514 https://reactome.org/PathwayBrowser/#/R-HSA-1433514 Synthesis of PIP3 from PIP2 by PI3K TAS Homo sapiens 57836 R-HSA-1433542 https://reactome.org/PathwayBrowser/#/R-HSA-1433542 Phosphorylation and activation of VAV1 TAS Homo sapiens 57836 R-HSA-162363 https://reactome.org/PathwayBrowser/#/R-HSA-162363 p-T309,S474-AKT2:PIP3 phosphorylates PDE3B IEA Homo sapiens 57836 R-HSA-165162 https://reactome.org/PathwayBrowser/#/R-HSA-165162 Phosphorylation of TSC2 by PKB TAS Homo sapiens 57836 R-HSA-165182 https://reactome.org/PathwayBrowser/#/R-HSA-165182 Phosphorylation of complexed TSC2 by PKB TAS Homo sapiens 57836 R-HSA-1675773 https://reactome.org/PathwayBrowser/#/R-HSA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane TAS Homo sapiens 57836 R-HSA-1675949 https://reactome.org/PathwayBrowser/#/R-HSA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane TAS Homo sapiens 57836 R-HSA-1676048 https://reactome.org/PathwayBrowser/#/R-HSA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane TAS Homo sapiens 57836 R-HSA-177923 https://reactome.org/PathwayBrowser/#/R-HSA-177923 Sustained activation of SRC kinase by SHP2 TAS Homo sapiens 57836 R-HSA-177924 https://reactome.org/PathwayBrowser/#/R-HSA-177924 Dephosphorylation of Gab1 by SHP2 TAS Homo sapiens 57836 R-HSA-177926 https://reactome.org/PathwayBrowser/#/R-HSA-177926 Dephosphorylation of PAG by SHP2 TAS Homo sapiens 57836 R-HSA-177927 https://reactome.org/PathwayBrowser/#/R-HSA-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 TAS Homo sapiens 57836 R-HSA-177930 https://reactome.org/PathwayBrowser/#/R-HSA-177930 GAB1 phosphorylation by EGFR kinase TAS Homo sapiens 57836 R-HSA-177935 https://reactome.org/PathwayBrowser/#/R-HSA-177935 SHP2 dephosphorylates Tyr 992 on EGFR TAS Homo sapiens 57836 R-HSA-177939 https://reactome.org/PathwayBrowser/#/R-HSA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) TAS Homo sapiens 57836 R-HSA-177941 https://reactome.org/PathwayBrowser/#/R-HSA-177941 GRB2:GAB1 binds to phosphorylated EGFR TAS Homo sapiens 57836 R-HSA-177944 https://reactome.org/PathwayBrowser/#/R-HSA-177944 Activation of SHP2 through the binding to phospho-Gab1 TAS Homo sapiens 57836 R-HSA-179467 https://reactome.org/PathwayBrowser/#/R-HSA-179467 GAB1 binds phosphatidylinositol-3,4,5-trisphosphate TAS Homo sapiens 57836 R-HSA-1839091 https://reactome.org/PathwayBrowser/#/R-HSA-1839091 Cytosolic FGFR1 fusion protein-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-1839094 https://reactome.org/PathwayBrowser/#/R-HSA-1839094 Activated FGFR1 mutants and fusions bind PLCG1 TAS Homo sapiens 57836 R-HSA-1839098 https://reactome.org/PathwayBrowser/#/R-HSA-1839098 Activated FGFR1 mutants and fusions phosphorylate PLCG1 TAS Homo sapiens 57836 R-HSA-1839107 https://reactome.org/PathwayBrowser/#/R-HSA-1839107 BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3. TAS Homo sapiens 57836 R-HSA-186800 https://reactome.org/PathwayBrowser/#/R-HSA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-198266 https://reactome.org/PathwayBrowser/#/R-HSA-198266 PI3K produces PIP3 and other phosphatidyl inositides TAS Homo sapiens 57836 R-HSA-198270 https://reactome.org/PathwayBrowser/#/R-HSA-198270 PDPK1 phosphorylates AKT at T308 TAS Homo sapiens 57836 R-HSA-198640 https://reactome.org/PathwayBrowser/#/R-HSA-198640 TORC2 (mTOR) phosphorylates AKT at S473 TAS Homo sapiens 57836 R-HSA-199443 https://reactome.org/PathwayBrowser/#/R-HSA-199443 THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation TAS Homo sapiens 57836 R-HSA-199456 https://reactome.org/PathwayBrowser/#/R-HSA-199456 PTEN dephosphorylates PIP3 TAS Homo sapiens 57836 R-HSA-201510 https://reactome.org/PathwayBrowser/#/R-HSA-201510 PI3K synthesizes PIP3 downstream of ALK TAS Homo sapiens 57836 R-HSA-202164 https://reactome.org/PathwayBrowser/#/R-HSA-202164 Translocation of PDK1 to Plasma membrane TAS Homo sapiens 57836 R-HSA-202222 https://reactome.org/PathwayBrowser/#/R-HSA-202222 Phosphorylation of PKC theta TAS Homo sapiens 57836 R-HSA-202237 https://reactome.org/PathwayBrowser/#/R-HSA-202237 Hydrolysis of PIP3 to PI(3,4)P2 TAS Homo sapiens 57836 R-HSA-202365 https://reactome.org/PathwayBrowser/#/R-HSA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-202394 https://reactome.org/PathwayBrowser/#/R-HSA-202394 Translocation of CARMA1 to Plasma membrane TAS Homo sapiens 57836 R-HSA-202437 https://reactome.org/PathwayBrowser/#/R-HSA-202437 Phosphorylation of CARMA1 TAS Homo sapiens 57836 R-HSA-202443 https://reactome.org/PathwayBrowser/#/R-HSA-202443 Oligomerization of CARMA1 TAS Homo sapiens 57836 R-HSA-202453 https://reactome.org/PathwayBrowser/#/R-HSA-202453 Auto-ubiquitination of TRAF6 TAS Homo sapiens 57836 R-HSA-202459 https://reactome.org/PathwayBrowser/#/R-HSA-202459 Phosphorylation of Bcl10 TAS Homo sapiens 57836 R-HSA-202466 https://reactome.org/PathwayBrowser/#/R-HSA-202466 Interaction of Bcl10 to CARMA1 TAS Homo sapiens 57836 R-HSA-202472 https://reactome.org/PathwayBrowser/#/R-HSA-202472 Translocation of TRAF6 to CBM complex TAS Homo sapiens 57836 R-HSA-202478 https://reactome.org/PathwayBrowser/#/R-HSA-202478 Interaction and oligomerization of MALT1 to Bcl10 TAS Homo sapiens 57836 R-HSA-202489 https://reactome.org/PathwayBrowser/#/R-HSA-202489 Oligomerization of Bcl10 TAS Homo sapiens 57836 R-HSA-202500 https://reactome.org/PathwayBrowser/#/R-HSA-202500 Activation of IKK complex TAS Homo sapiens 57836 R-HSA-202510 https://reactome.org/PathwayBrowser/#/R-HSA-202510 Activation of TAK1-TAB2 complex TAS Homo sapiens 57836 R-HSA-202534 https://reactome.org/PathwayBrowser/#/R-HSA-202534 Ubiquitination of NEMO by TRAF6 TAS Homo sapiens 57836 R-HSA-202692 https://reactome.org/PathwayBrowser/#/R-HSA-202692 PIP3 binds to RhoA and activates it TAS Homo sapiens 57836 R-HSA-2029268 https://reactome.org/PathwayBrowser/#/R-HSA-2029268 Phosphorylation and activation of PLCG TAS Homo sapiens 57836 R-HSA-2029271 https://reactome.org/PathwayBrowser/#/R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-2029272 https://reactome.org/PathwayBrowser/#/R-HSA-2029272 Release of PLCG from FCGR TAS Homo sapiens 57836 R-HSA-2029453 https://reactome.org/PathwayBrowser/#/R-HSA-2029453 Phosphorylation of VAV TAS Homo sapiens 57836 R-HSA-2029458 https://reactome.org/PathwayBrowser/#/R-HSA-2029458 Recruitment of VAV1 to p-6Y-SYK TAS Homo sapiens 57836 R-HSA-2029465 https://reactome.org/PathwayBrowser/#/R-HSA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) TAS Homo sapiens 57836 R-HSA-2029466 https://reactome.org/PathwayBrowser/#/R-HSA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin TAS Homo sapiens 57836 R-HSA-2029469 https://reactome.org/PathwayBrowser/#/R-HSA-2029469 p-ERK phosphorylates WAVEs and ABI TAS Homo sapiens 57836 R-HSA-2045911 https://reactome.org/PathwayBrowser/#/R-HSA-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 TAS Homo sapiens 57836 R-HSA-2076220 https://reactome.org/PathwayBrowser/#/R-HSA-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 TAS Homo sapiens 57836 R-HSA-2130194 https://reactome.org/PathwayBrowser/#/R-HSA-2130194 ABL phosphorylates WAVEs TAS Homo sapiens 57836 R-HSA-2197690 https://reactome.org/PathwayBrowser/#/R-HSA-2197690 Detachment of WASP/WAVE TAS Homo sapiens 57836 R-HSA-2316429 https://reactome.org/PathwayBrowser/#/R-HSA-2316429 PIP3 recruits PDPK1 to the membrane TAS Homo sapiens 57836 R-HSA-2316434 https://reactome.org/PathwayBrowser/#/R-HSA-2316434 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-2317314 https://reactome.org/PathwayBrowser/#/R-HSA-2317314 AKT binds PDPK1 TAS Homo sapiens 57836 R-HSA-2317332 https://reactome.org/PathwayBrowser/#/R-HSA-2317332 PIP3 recruits AKT to the membrane TAS Homo sapiens 57836 R-HSA-2317387 https://reactome.org/PathwayBrowser/#/R-HSA-2317387 PTEN cancer mutants do not dephosphorylate PIP3 TAS Homo sapiens 57836 R-HSA-2394007 https://reactome.org/PathwayBrowser/#/R-HSA-2394007 PI3K gain of function mutants phosphorylate PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 57836 R-HSA-2424476 https://reactome.org/PathwayBrowser/#/R-HSA-2424476 Activation of RAC1 by VAV2/3 TAS Homo sapiens 57836 R-HSA-2424480 https://reactome.org/PathwayBrowser/#/R-HSA-2424480 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-2424481 https://reactome.org/PathwayBrowser/#/R-HSA-2424481 Recruitment of VAV and BTK to p-SLP-76 TAS Homo sapiens 57836 R-HSA-2424484 https://reactome.org/PathwayBrowser/#/R-HSA-2424484 Phosphorylation of BTK by p-SYK TAS Homo sapiens 57836 R-HSA-2424485 https://reactome.org/PathwayBrowser/#/R-HSA-2424485 Release of p-PLCG1 TAS Homo sapiens 57836 R-HSA-2424486 https://reactome.org/PathwayBrowser/#/R-HSA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK TAS Homo sapiens 57836 R-HSA-2424487 https://reactome.org/PathwayBrowser/#/R-HSA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK TAS Homo sapiens 57836 R-HSA-2730833 https://reactome.org/PathwayBrowser/#/R-HSA-2730833 Phosphorylation of TEC kinases by p-SYK TAS Homo sapiens 57836 R-HSA-2730840 https://reactome.org/PathwayBrowser/#/R-HSA-2730840 Activation of RAC1 by VAV TAS Homo sapiens 57836 R-HSA-2730841 https://reactome.org/PathwayBrowser/#/R-HSA-2730841 Phosphorylation and activation of VAV TAS Homo sapiens 57836 R-HSA-2730842 https://reactome.org/PathwayBrowser/#/R-HSA-2730842 PI3K associates with phosphorylated GAB2 TAS Homo sapiens 57836 R-HSA-2730847 https://reactome.org/PathwayBrowser/#/R-HSA-2730847 Hydrolysis of PIP2 by PLCG TAS Homo sapiens 57836 R-HSA-2730848 https://reactome.org/PathwayBrowser/#/R-HSA-2730848 Recruitment of GAB2 to PM and FCERI by binding to GRB2 IEA Homo sapiens 57836 R-HSA-2730856 https://reactome.org/PathwayBrowser/#/R-HSA-2730856 Autophosphorylation of PAK TAS Homo sapiens 57836 R-HSA-2730858 https://reactome.org/PathwayBrowser/#/R-HSA-2730858 Autophosphorylation of BTK/ITK TAS Homo sapiens 57836 R-HSA-2730860 https://reactome.org/PathwayBrowser/#/R-HSA-2730860 Phosphorylation of GAB2 by SYK/FYN IEA Homo sapiens 57836 R-HSA-2730870 https://reactome.org/PathwayBrowser/#/R-HSA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K TAS Homo sapiens 57836 R-HSA-2730885 https://reactome.org/PathwayBrowser/#/R-HSA-2730885 Recruitment of TEC kinases to p-SLP-76 IEA Homo sapiens 57836 R-HSA-2730888 https://reactome.org/PathwayBrowser/#/R-HSA-2730888 Phosphorylation of PLC-gamma IEA Homo sapiens 57836 R-HSA-2730889 https://reactome.org/PathwayBrowser/#/R-HSA-2730889 Recruitment of PAK to the membrane by binding active RAC1 TAS Homo sapiens 57836 R-HSA-389158 https://reactome.org/PathwayBrowser/#/R-HSA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-389348 https://reactome.org/PathwayBrowser/#/R-HSA-389348 Activation of Rac1 by pVav1 TAS Homo sapiens 57836 R-HSA-389350 https://reactome.org/PathwayBrowser/#/R-HSA-389350 Activation of Cdc42 by pVav1 TAS Homo sapiens 57836 R-HSA-389352 https://reactome.org/PathwayBrowser/#/R-HSA-389352 Translocation of Vav1 to CD28 TAS Homo sapiens 57836 R-HSA-389354 https://reactome.org/PathwayBrowser/#/R-HSA-389354 Activation of Vav1 TAS Homo sapiens 57836 R-HSA-392300 https://reactome.org/PathwayBrowser/#/R-HSA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-434637 https://reactome.org/PathwayBrowser/#/R-HSA-434637 PI(3,4,5)P3 binds VAV1,2,3 IEA Homo sapiens 57836 R-HSA-437162 https://reactome.org/PathwayBrowser/#/R-HSA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-437192 https://reactome.org/PathwayBrowser/#/R-HSA-437192 PDPK1 binds PRKCZ IEA Homo sapiens 57836 R-HSA-437195 https://reactome.org/PathwayBrowser/#/R-HSA-437195 PDPK1 activates PRKCZ IEA Homo sapiens 57836 R-HSA-442273 https://reactome.org/PathwayBrowser/#/R-HSA-442273 VAV1 is a GEF for Rho/Rac family GTPases TAS Homo sapiens 57836 R-HSA-442592 https://reactome.org/PathwayBrowser/#/R-HSA-442592 WASPs or WAVEs activate the ARP2/3 complex IEA Homo sapiens 57836 R-HSA-442739 https://reactome.org/PathwayBrowser/#/R-HSA-442739 PDPK1 phosphorylates RSKs IEA Homo sapiens 57836 R-HSA-449058 https://reactome.org/PathwayBrowser/#/R-HSA-449058 Interleukin-1 family are secreted TAS Homo sapiens 57836 R-HSA-5218819 https://reactome.org/PathwayBrowser/#/R-HSA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5218820 https://reactome.org/PathwayBrowser/#/R-HSA-5218820 Src kinases phosphorylate VAV TAS Homo sapiens 57836 R-HSA-5218850 https://reactome.org/PathwayBrowser/#/R-HSA-5218850 VAV exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 57836 R-HSA-5357445 https://reactome.org/PathwayBrowser/#/R-HSA-5357445 PAK1-3 dimer disassociates TAS Homo sapiens 57836 R-HSA-5357472 https://reactome.org/PathwayBrowser/#/R-HSA-5357472 PAK1-3 autophosphorylates TAS Homo sapiens 57836 R-HSA-5357483 https://reactome.org/PathwayBrowser/#/R-HSA-5357483 RAC1 binds PAK1-3 TAS Homo sapiens 57836 R-HSA-5620975 https://reactome.org/PathwayBrowser/#/R-HSA-5620975 MLKL binds PIPs TAS Homo sapiens 57836 R-HSA-5623632 https://reactome.org/PathwayBrowser/#/R-HSA-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 TAS Homo sapiens 57836 R-HSA-5623667 https://reactome.org/PathwayBrowser/#/R-HSA-5623667 PDPK1 phosphorylates PKN1,2,3 TAS Homo sapiens 57836 R-HSA-5637801 https://reactome.org/PathwayBrowser/#/R-HSA-5637801 Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII TAS Homo sapiens 57836 R-HSA-5654147 https://reactome.org/PathwayBrowser/#/R-HSA-5654147 Activated FGFR2 phosphorylates PLCG1 TAS Homo sapiens 57836 R-HSA-5654149 https://reactome.org/PathwayBrowser/#/R-HSA-5654149 Activated FGFR1 phosphorylates PLCG1 TAS Homo sapiens 57836 R-HSA-5654151 https://reactome.org/PathwayBrowser/#/R-HSA-5654151 Activated FGFR4 phosphorylates PLCG1 TAS Homo sapiens 57836 R-HSA-5654159 https://reactome.org/PathwayBrowser/#/R-HSA-5654159 Activated FGFR2 binds PLCG1 TAS Homo sapiens 57836 R-HSA-5654163 https://reactome.org/PathwayBrowser/#/R-HSA-5654163 Activated FGFR4 binds PLCG1 TAS Homo sapiens 57836 R-HSA-5654167 https://reactome.org/PathwayBrowser/#/R-HSA-5654167 Activated FGFR1 binds PLCG1 TAS Homo sapiens 57836 R-HSA-5654222 https://reactome.org/PathwayBrowser/#/R-HSA-5654222 Activated FGFR3 phosphorylates PLCG1 TAS Homo sapiens 57836 R-HSA-5654224 https://reactome.org/PathwayBrowser/#/R-HSA-5654224 Activated FGFR3 binds PLCG1 TAS Homo sapiens 57836 R-HSA-5654690 https://reactome.org/PathwayBrowser/#/R-HSA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5654692 https://reactome.org/PathwayBrowser/#/R-HSA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5654697 https://reactome.org/PathwayBrowser/#/R-HSA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5654701 https://reactome.org/PathwayBrowser/#/R-HSA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5654705 https://reactome.org/PathwayBrowser/#/R-HSA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5654709 https://reactome.org/PathwayBrowser/#/R-HSA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5654714 https://reactome.org/PathwayBrowser/#/R-HSA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5654717 https://reactome.org/PathwayBrowser/#/R-HSA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5655235 https://reactome.org/PathwayBrowser/#/R-HSA-5655235 Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5655243 https://reactome.org/PathwayBrowser/#/R-HSA-5655243 Activated FGFR3 point and translocation mutants phosphorylate PLCG1 TAS Homo sapiens 57836 R-HSA-5655244 https://reactome.org/PathwayBrowser/#/R-HSA-5655244 Activated FGFR3 point and translocation mutants bind PLCG1 TAS Homo sapiens 57836 R-HSA-5655289 https://reactome.org/PathwayBrowser/#/R-HSA-5655289 Activated FGFR3 point, translocation and fusion mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5655290 https://reactome.org/PathwayBrowser/#/R-HSA-5655290 Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5655301 https://reactome.org/PathwayBrowser/#/R-HSA-5655301 Activated FGFR2 mutants phosphorylate PLCG1 TAS Homo sapiens 57836 R-HSA-5655313 https://reactome.org/PathwayBrowser/#/R-HSA-5655313 Activated FGFR4 mutants bind PLCG1 TAS Homo sapiens 57836 R-HSA-5655323 https://reactome.org/PathwayBrowser/#/R-HSA-5655323 Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-5655341 https://reactome.org/PathwayBrowser/#/R-HSA-5655341 Activated FGFR4 mutants phosphorylate PLCG1 TAS Homo sapiens 57836 R-HSA-5655343 https://reactome.org/PathwayBrowser/#/R-HSA-5655343 Activated FGFR2 mutants bind PLCG1 TAS Homo sapiens 57836 R-HSA-6795473 https://reactome.org/PathwayBrowser/#/R-HSA-6795473 PDPK1 phosphorylates SGK1 TAS Homo sapiens 57836 R-HSA-6805981 https://reactome.org/PathwayBrowser/#/R-HSA-6805981 HMGB1 release from cells TAS Homo sapiens 57836 R-HSA-8849969 https://reactome.org/PathwayBrowser/#/R-HSA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane TAS Homo sapiens 57836 R-HSA-8852019 https://reactome.org/PathwayBrowser/#/R-HSA-8852019 MET bound PI3K generates PIP3 TAS Homo sapiens 57836 R-HSA-8874470 https://reactome.org/PathwayBrowser/#/R-HSA-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane TAS Homo sapiens 57836 R-HSA-8951586 https://reactome.org/PathwayBrowser/#/R-HSA-8951586 p-VAV family:PIP3 binds RAC1:GDP TAS Homo sapiens 57836 R-HSA-8964241 https://reactome.org/PathwayBrowser/#/R-HSA-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane TAS Homo sapiens 57836 R-HSA-8964271 https://reactome.org/PathwayBrowser/#/R-HSA-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated TAS Homo sapiens 57836 R-HSA-8964317 https://reactome.org/PathwayBrowser/#/R-HSA-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex TAS Homo sapiens 57836 R-HSA-9021627 https://reactome.org/PathwayBrowser/#/R-HSA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-9028519 https://reactome.org/PathwayBrowser/#/R-HSA-9028519 NTRK2-activated PI3K generates PIP3 IEA Homo sapiens 57836 R-HSA-917693 https://reactome.org/PathwayBrowser/#/R-HSA-917693 ESCRT Disassembly TAS Homo sapiens 57836 R-HSA-917696 https://reactome.org/PathwayBrowser/#/R-HSA-917696 Cargo Sequestration TAS Homo sapiens 57836 R-HSA-917700 https://reactome.org/PathwayBrowser/#/R-HSA-917700 MVB Vesicle Formation TAS Homo sapiens 57836 R-HSA-917730 https://reactome.org/PathwayBrowser/#/R-HSA-917730 Cargo Recognition And Sorting TAS Homo sapiens 57836 R-HSA-9603279 https://reactome.org/PathwayBrowser/#/R-HSA-9603279 PIP3 recruits PDK1 and AKT to the membrane TAS Homo sapiens 57836 R-HSA-9603445 https://reactome.org/PathwayBrowser/#/R-HSA-9603445 Activated NTRK3 stimulates PI3K activity IEA Homo sapiens 57836 R-HSA-9606151 https://reactome.org/PathwayBrowser/#/R-HSA-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 TAS Homo sapiens 57836 R-HSA-9606159 https://reactome.org/PathwayBrowser/#/R-HSA-9606159 BTK autophosphorylates IEA Homo sapiens 57836 R-HSA-9606162 https://reactome.org/PathwayBrowser/#/R-HSA-9606162 Phosphorylated BTK phosphorylates PLCG2 IEA Homo sapiens 57836 R-HSA-9606163 https://reactome.org/PathwayBrowser/#/R-HSA-9606163 p-SYK and LYN phosphorylate BTK IEA Homo sapiens 57836 R-HSA-9606884 https://reactome.org/PathwayBrowser/#/R-HSA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated TAS Homo sapiens 57836 R-HSA-9606894 https://reactome.org/PathwayBrowser/#/R-HSA-9606894 p-DAPP1 (p-BAM32) binds PLCG2 TAS Homo sapiens 57836 R-HSA-9632858 https://reactome.org/PathwayBrowser/#/R-HSA-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation TAS Homo sapiens 57836 R-HSA-9632906 https://reactome.org/PathwayBrowser/#/R-HSA-9632906 PRKCZ recruits RAS in response to estrogen stimulation TAS Homo sapiens 57836 R-HSA-9632910 https://reactome.org/PathwayBrowser/#/R-HSA-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus TAS Homo sapiens 57836 R-HSA-9632918 https://reactome.org/PathwayBrowser/#/R-HSA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen TAS Homo sapiens 57836 R-HSA-9647619 https://reactome.org/PathwayBrowser/#/R-HSA-9647619 GSDMD forms ring‐shaped oligomers TAS Homo sapiens 57836 R-HSA-9647631 https://reactome.org/PathwayBrowser/#/R-HSA-9647631 GSDMD (1-275) binds PIPs TAS Homo sapiens 57836 R-HSA-9647645 https://reactome.org/PathwayBrowser/#/R-HSA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures TAS Homo sapiens 57836 R-HSA-9647660 https://reactome.org/PathwayBrowser/#/R-HSA-9647660 GSDME (1-270) binds PIPs TAS Homo sapiens 57836 R-HSA-9664271 https://reactome.org/PathwayBrowser/#/R-HSA-9664271 Release of PLCG from FCGR3A TAS Homo sapiens 57836 R-HSA-9664278 https://reactome.org/PathwayBrowser/#/R-HSA-9664278 Phosphorylation and activation of PLCG due to FCGR3A effect TAS Homo sapiens 57836 R-HSA-9664664 https://reactome.org/PathwayBrowser/#/R-HSA-9664664 PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 converts PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-9664940 https://reactome.org/PathwayBrowser/#/R-HSA-9664940 PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR converts PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-9665407 https://reactome.org/PathwayBrowser/#/R-HSA-9665407 PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3 TAS Homo sapiens 57836 R-HSA-9666425 https://reactome.org/PathwayBrowser/#/R-HSA-9666425 p-6Y-SYK phosphorylates VAV1,2,3 TAS Homo sapiens 57836 R-HSA-9666430 https://reactome.org/PathwayBrowser/#/R-HSA-9666430 p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens 57836 R-HSA-9666435 https://reactome.org/PathwayBrowser/#/R-HSA-9666435 VAV1,2,3:PI(3,4,5)P3 binds p-6Y-SYK TAS Homo sapiens 57836 R-HSA-9670433 https://reactome.org/PathwayBrowser/#/R-HSA-9670433 KIT mutants:PI3K catalyze synthesis of PIP3 TAS Homo sapiens 57836 R-HSA-9672162 https://reactome.org/PathwayBrowser/#/R-HSA-9672162 PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of PDGFRA extracellular domain dimers TAS Homo sapiens 57836 R-HSA-9672177 https://reactome.org/PathwayBrowser/#/R-HSA-9672177 PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of mutant PDGFR TAS Homo sapiens 57836 R-HSA-9680389 https://reactome.org/PathwayBrowser/#/R-HSA-9680389 CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2 IEA Homo sapiens 57836 R-HSA-9691421 https://reactome.org/PathwayBrowser/#/R-HSA-9691421 BTK binds BTK inhibitors TAS Homo sapiens 57836 R-HSA-9700149 https://reactome.org/PathwayBrowser/#/R-HSA-9700149 Active ALK binds PLCG1 TAS Homo sapiens 57836 R-HSA-9700171 https://reactome.org/PathwayBrowser/#/R-HSA-9700171 Active ALK phosphorylates PLCG1 TAS Homo sapiens 57836 R-HSA-9710254 https://reactome.org/PathwayBrowser/#/R-HSA-9710254 GSDME oligomerizes TAS Homo sapiens 57836 R-HSA-9710468 https://reactome.org/PathwayBrowser/#/R-HSA-9710468 GSDME variant does not bind PIPs TAS Homo sapiens 57836 R-HSA-9710917 https://reactome.org/PathwayBrowser/#/R-HSA-9710917 ALK fusion proteins bind PLCG1 TAS Homo sapiens 57836 R-HSA-9712084 https://reactome.org/PathwayBrowser/#/R-HSA-9712084 PI3K synthesizes PIP3 downstream of ALK mutants TAS Homo sapiens 57836 R-HSA-9712086 https://reactome.org/PathwayBrowser/#/R-HSA-9712086 ALK fusions phosphorylate PLCG1 TAS Homo sapiens 57836 R-MMU-109699 https://reactome.org/PathwayBrowser/#/R-MMU-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-109700 https://reactome.org/PathwayBrowser/#/R-MMU-109700 AKT2 binds PIP3 IEA Mus musculus 57836 R-MMU-109701 https://reactome.org/PathwayBrowser/#/R-MMU-109701 PDPK1 binds PIP3 IEA Mus musculus 57836 R-MMU-109702 https://reactome.org/PathwayBrowser/#/R-MMU-109702 PDPK1 phosphorylates AKT2 IEA Mus musculus 57836 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus 57836 R-MMU-1250370 https://reactome.org/PathwayBrowser/#/R-MMU-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Mus musculus 57836 R-MMU-1250462 https://reactome.org/PathwayBrowser/#/R-MMU-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Mus musculus 57836 R-MMU-1306957 https://reactome.org/PathwayBrowser/#/R-MMU-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Mus musculus 57836 R-MMU-1306979 https://reactome.org/PathwayBrowser/#/R-MMU-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Mus musculus 57836 R-MMU-1433415 https://reactome.org/PathwayBrowser/#/R-MMU-1433415 Activation of RAC1 IEA Mus musculus 57836 R-MMU-1433514 https://reactome.org/PathwayBrowser/#/R-MMU-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Mus musculus 57836 R-MMU-1433542 https://reactome.org/PathwayBrowser/#/R-MMU-1433542 Phosphorylation and activation of VAV1 IEA Mus musculus 57836 R-MMU-165162 https://reactome.org/PathwayBrowser/#/R-MMU-165162 Phosphorylation of TSC2 by PKB IEA Mus musculus 57836 R-MMU-165182 https://reactome.org/PathwayBrowser/#/R-MMU-165182 Phosphorylation of complexed TSC2 by PKB IEA Mus musculus 57836 R-MMU-1675773 https://reactome.org/PathwayBrowser/#/R-MMU-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Mus musculus 57836 R-MMU-1675949 https://reactome.org/PathwayBrowser/#/R-MMU-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Mus musculus 57836 R-MMU-1676048 https://reactome.org/PathwayBrowser/#/R-MMU-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Mus musculus 57836 R-MMU-177923 https://reactome.org/PathwayBrowser/#/R-MMU-177923 Sustained activation of SRC kinase by SHP2 IEA Mus musculus 57836 R-MMU-177924 https://reactome.org/PathwayBrowser/#/R-MMU-177924 Dephosphorylation of Gab1 by SHP2 IEA Mus musculus 57836 R-MMU-177926 https://reactome.org/PathwayBrowser/#/R-MMU-177926 Dephosphorylation of PAG by SHP2 IEA Mus musculus 57836 R-MMU-177927 https://reactome.org/PathwayBrowser/#/R-MMU-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Mus musculus 57836 R-MMU-177930 https://reactome.org/PathwayBrowser/#/R-MMU-177930 GAB1 phosphorylation by EGFR kinase IEA Mus musculus 57836 R-MMU-177935 https://reactome.org/PathwayBrowser/#/R-MMU-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Mus musculus 57836 R-MMU-177939 https://reactome.org/PathwayBrowser/#/R-MMU-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Mus musculus 57836 R-MMU-177941 https://reactome.org/PathwayBrowser/#/R-MMU-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Mus musculus 57836 R-MMU-177944 https://reactome.org/PathwayBrowser/#/R-MMU-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Mus musculus 57836 R-MMU-179467 https://reactome.org/PathwayBrowser/#/R-MMU-179467 GAB1 binds phosphatidylinositol-3,4,5-trisphosphate IEA Mus musculus 57836 R-MMU-186800 https://reactome.org/PathwayBrowser/#/R-MMU-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-198266 https://reactome.org/PathwayBrowser/#/R-MMU-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Mus musculus 57836 R-MMU-198640 https://reactome.org/PathwayBrowser/#/R-MMU-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Mus musculus 57836 R-MMU-199443 https://reactome.org/PathwayBrowser/#/R-MMU-199443 THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation IEA Mus musculus 57836 R-MMU-199456 https://reactome.org/PathwayBrowser/#/R-MMU-199456 PTEN dephosphorylates PIP3 IEA Mus musculus 57836 R-MMU-201510 https://reactome.org/PathwayBrowser/#/R-MMU-201510 PI3K synthesizes PIP3 downstream of ALK IEA Mus musculus 57836 R-MMU-202164 https://reactome.org/PathwayBrowser/#/R-MMU-202164 Translocation of PDK1 to Plasma membrane IEA Mus musculus 57836 R-MMU-202222 https://reactome.org/PathwayBrowser/#/R-MMU-202222 Phosphorylation of PKC theta IEA Mus musculus 57836 R-MMU-202237 https://reactome.org/PathwayBrowser/#/R-MMU-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Mus musculus 57836 R-MMU-202365 https://reactome.org/PathwayBrowser/#/R-MMU-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-202394 https://reactome.org/PathwayBrowser/#/R-MMU-202394 Translocation of CARMA1 to Plasma membrane IEA Mus musculus 57836 R-MMU-202437 https://reactome.org/PathwayBrowser/#/R-MMU-202437 Phosphorylation of CARMA1 IEA Mus musculus 57836 R-MMU-202443 https://reactome.org/PathwayBrowser/#/R-MMU-202443 Oligomerization of CARMA1 IEA Mus musculus 57836 R-MMU-202453 https://reactome.org/PathwayBrowser/#/R-MMU-202453 Auto-ubiquitination of TRAF6 IEA Mus musculus 57836 R-MMU-202459 https://reactome.org/PathwayBrowser/#/R-MMU-202459 Phosphorylation of Bcl10 IEA Mus musculus 57836 R-MMU-202466 https://reactome.org/PathwayBrowser/#/R-MMU-202466 Interaction of Bcl10 to CARMA1 IEA Mus musculus 57836 R-MMU-202472 https://reactome.org/PathwayBrowser/#/R-MMU-202472 Translocation of TRAF6 to CBM complex IEA Mus musculus 57836 R-MMU-202478 https://reactome.org/PathwayBrowser/#/R-MMU-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Mus musculus 57836 R-MMU-202489 https://reactome.org/PathwayBrowser/#/R-MMU-202489 Oligomerization of Bcl10 IEA Mus musculus 57836 R-MMU-202500 https://reactome.org/PathwayBrowser/#/R-MMU-202500 Activation of IKK complex IEA Mus musculus 57836 R-MMU-202510 https://reactome.org/PathwayBrowser/#/R-MMU-202510 Activation of TAK1-TAB2 complex IEA Mus musculus 57836 R-MMU-202534 https://reactome.org/PathwayBrowser/#/R-MMU-202534 Ubiquitination of NEMO by TRAF6 IEA Mus musculus 57836 R-MMU-202692 https://reactome.org/PathwayBrowser/#/R-MMU-202692 PIP3 binds to RhoA and activates it IEA Mus musculus 57836 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus 57836 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus 57836 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus 57836 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus 57836 R-MMU-2029465 https://reactome.org/PathwayBrowser/#/R-MMU-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Mus musculus 57836 R-MMU-2029466 https://reactome.org/PathwayBrowser/#/R-MMU-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Mus musculus 57836 R-MMU-2029469 https://reactome.org/PathwayBrowser/#/R-MMU-2029469 p-ERK phosphorylates WAVEs and ABI IEA Mus musculus 57836 R-MMU-2045911 https://reactome.org/PathwayBrowser/#/R-MMU-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Mus musculus 57836 R-MMU-2076220 https://reactome.org/PathwayBrowser/#/R-MMU-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Mus musculus 57836 R-MMU-2130194 https://reactome.org/PathwayBrowser/#/R-MMU-2130194 ABL phosphorylates WAVEs IEA Mus musculus 57836 R-MMU-2197690 https://reactome.org/PathwayBrowser/#/R-MMU-2197690 Detachment of WASP/WAVE IEA Mus musculus 57836 R-MMU-2316429 https://reactome.org/PathwayBrowser/#/R-MMU-2316429 PIP3 recruits PDPK1 to the membrane IEA Mus musculus 57836 R-MMU-2316434 https://reactome.org/PathwayBrowser/#/R-MMU-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-2317314 https://reactome.org/PathwayBrowser/#/R-MMU-2317314 AKT binds PDPK1 IEA Mus musculus 57836 R-MMU-2317332 https://reactome.org/PathwayBrowser/#/R-MMU-2317332 PIP3 recruits AKT to the membrane IEA Mus musculus 57836 R-MMU-2424476 https://reactome.org/PathwayBrowser/#/R-MMU-2424476 Activation of RAC1 by VAV2/3 IEA Mus musculus 57836 R-MMU-2424480 https://reactome.org/PathwayBrowser/#/R-MMU-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-2424481 https://reactome.org/PathwayBrowser/#/R-MMU-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Mus musculus 57836 R-MMU-2424484 https://reactome.org/PathwayBrowser/#/R-MMU-2424484 Phosphorylation of BTK by p-SYK IEA Mus musculus 57836 R-MMU-2424485 https://reactome.org/PathwayBrowser/#/R-MMU-2424485 Release of p-PLCG1 IEA Mus musculus 57836 R-MMU-2424486 https://reactome.org/PathwayBrowser/#/R-MMU-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Mus musculus 57836 R-MMU-2424487 https://reactome.org/PathwayBrowser/#/R-MMU-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Mus musculus 57836 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus 57836 R-MMU-2730840 https://reactome.org/PathwayBrowser/#/R-MMU-2730840 Activation of RAC1 by VAV IEA Mus musculus 57836 R-MMU-2730841 https://reactome.org/PathwayBrowser/#/R-MMU-2730841 Phosphorylation and activation of VAV IEA Mus musculus 57836 R-MMU-2730842 https://reactome.org/PathwayBrowser/#/R-MMU-2730842 PI3K associates with phosphorylated GAB2 IEA Mus musculus 57836 R-MMU-2730847 https://reactome.org/PathwayBrowser/#/R-MMU-2730847 Hydrolysis of PIP2 by PLCG IEA Mus musculus 57836 R-MMU-2730850 https://reactome.org/PathwayBrowser/#/R-MMU-2730850 Recruitment of Tec kinases to p-Slp-76 TAS Mus musculus 57836 R-MMU-2730856 https://reactome.org/PathwayBrowser/#/R-MMU-2730856 Autophosphorylation of PAK IEA Mus musculus 57836 R-MMU-2730858 https://reactome.org/PathwayBrowser/#/R-MMU-2730858 Autophosphorylation of BTK/ITK IEA Mus musculus 57836 R-MMU-2730870 https://reactome.org/PathwayBrowser/#/R-MMU-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Mus musculus 57836 R-MMU-2730889 https://reactome.org/PathwayBrowser/#/R-MMU-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Mus musculus 57836 R-MMU-389158 https://reactome.org/PathwayBrowser/#/R-MMU-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-389348 https://reactome.org/PathwayBrowser/#/R-MMU-389348 Activation of Rac1 by pVav1 IEA Mus musculus 57836 R-MMU-389350 https://reactome.org/PathwayBrowser/#/R-MMU-389350 Activation of Cdc42 by pVav1 IEA Mus musculus 57836 R-MMU-389352 https://reactome.org/PathwayBrowser/#/R-MMU-389352 Translocation of Vav1 to CD28 IEA Mus musculus 57836 R-MMU-389354 https://reactome.org/PathwayBrowser/#/R-MMU-389354 Activation of Vav1 IEA Mus musculus 57836 R-MMU-392300 https://reactome.org/PathwayBrowser/#/R-MMU-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-434629 https://reactome.org/PathwayBrowser/#/R-MMU-434629 PIP3 stimulates Vav1 TAS Mus musculus 57836 R-MMU-437162 https://reactome.org/PathwayBrowser/#/R-MMU-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-442273 https://reactome.org/PathwayBrowser/#/R-MMU-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Mus musculus 57836 R-MMU-449058 https://reactome.org/PathwayBrowser/#/R-MMU-449058 Interleukin-1 family are secreted IEA Mus musculus 57836 R-MMU-5218819 https://reactome.org/PathwayBrowser/#/R-MMU-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-5218820 https://reactome.org/PathwayBrowser/#/R-MMU-5218820 Src kinases phosphorylate VAV IEA Mus musculus 57836 R-MMU-5218850 https://reactome.org/PathwayBrowser/#/R-MMU-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 57836 R-MMU-5357445 https://reactome.org/PathwayBrowser/#/R-MMU-5357445 PAK1-3 dimer disassociates IEA Mus musculus 57836 R-MMU-5357472 https://reactome.org/PathwayBrowser/#/R-MMU-5357472 PAK1-3 autophosphorylates IEA Mus musculus 57836 R-MMU-5357483 https://reactome.org/PathwayBrowser/#/R-MMU-5357483 RAC1 binds PAK1-3 IEA Mus musculus 57836 R-MMU-5620975 https://reactome.org/PathwayBrowser/#/R-MMU-5620975 MLKL binds PIPs IEA Mus musculus 57836 R-MMU-5623632 https://reactome.org/PathwayBrowser/#/R-MMU-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Mus musculus 57836 R-MMU-5623667 https://reactome.org/PathwayBrowser/#/R-MMU-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Mus musculus 57836 R-MMU-5654147 https://reactome.org/PathwayBrowser/#/R-MMU-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Mus musculus 57836 R-MMU-5654149 https://reactome.org/PathwayBrowser/#/R-MMU-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Mus musculus 57836 R-MMU-5654151 https://reactome.org/PathwayBrowser/#/R-MMU-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Mus musculus 57836 R-MMU-5654159 https://reactome.org/PathwayBrowser/#/R-MMU-5654159 Activated FGFR2 binds PLCG1 IEA Mus musculus 57836 R-MMU-5654163 https://reactome.org/PathwayBrowser/#/R-MMU-5654163 Activated FGFR4 binds PLCG1 IEA Mus musculus 57836 R-MMU-5654167 https://reactome.org/PathwayBrowser/#/R-MMU-5654167 Activated FGFR1 binds PLCG1 IEA Mus musculus 57836 R-MMU-5654222 https://reactome.org/PathwayBrowser/#/R-MMU-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Mus musculus 57836 R-MMU-5654224 https://reactome.org/PathwayBrowser/#/R-MMU-5654224 Activated FGFR3 binds PLCG1 IEA Mus musculus 57836 R-MMU-5654690 https://reactome.org/PathwayBrowser/#/R-MMU-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-5654692 https://reactome.org/PathwayBrowser/#/R-MMU-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-5654697 https://reactome.org/PathwayBrowser/#/R-MMU-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-5654701 https://reactome.org/PathwayBrowser/#/R-MMU-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-5654705 https://reactome.org/PathwayBrowser/#/R-MMU-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-5654709 https://reactome.org/PathwayBrowser/#/R-MMU-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-5654714 https://reactome.org/PathwayBrowser/#/R-MMU-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-5654717 https://reactome.org/PathwayBrowser/#/R-MMU-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-6795473 https://reactome.org/PathwayBrowser/#/R-MMU-6795473 PDPK1 phosphorylates SGK1 IEA Mus musculus 57836 R-MMU-6805981 https://reactome.org/PathwayBrowser/#/R-MMU-6805981 HMGB1 release from cells IEA Mus musculus 57836 R-MMU-8849969 https://reactome.org/PathwayBrowser/#/R-MMU-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Mus musculus 57836 R-MMU-8852019 https://reactome.org/PathwayBrowser/#/R-MMU-8852019 MET bound PI3K generates PIP3 IEA Mus musculus 57836 R-MMU-8874470 https://reactome.org/PathwayBrowser/#/R-MMU-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Mus musculus 57836 R-MMU-8951586 https://reactome.org/PathwayBrowser/#/R-MMU-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Mus musculus 57836 R-MMU-8964241 https://reactome.org/PathwayBrowser/#/R-MMU-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Mus musculus 57836 R-MMU-8964271 https://reactome.org/PathwayBrowser/#/R-MMU-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Mus musculus 57836 R-MMU-8964317 https://reactome.org/PathwayBrowser/#/R-MMU-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Mus musculus 57836 R-MMU-9021627 https://reactome.org/PathwayBrowser/#/R-MMU-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 57836 R-MMU-9031553 https://reactome.org/PathwayBrowser/#/R-MMU-9031553 Activated Ntrk2 activates PI3K signaling TAS Mus musculus 57836 R-MMU-917693 https://reactome.org/PathwayBrowser/#/R-MMU-917693 ESCRT Disassembly IEA Mus musculus 57836 R-MMU-917696 https://reactome.org/PathwayBrowser/#/R-MMU-917696 Cargo Sequestration IEA Mus musculus 57836 R-MMU-917700 https://reactome.org/PathwayBrowser/#/R-MMU-917700 MVB Vesicle Formation IEA Mus musculus 57836 R-MMU-917730 https://reactome.org/PathwayBrowser/#/R-MMU-917730 Cargo Recognition And Sorting IEA Mus musculus 57836 R-MMU-9603279 https://reactome.org/PathwayBrowser/#/R-MMU-9603279 PIP3 recruits PDK1 and AKT to the membrane IEA Mus musculus 57836 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus 57836 R-MMU-9606884 https://reactome.org/PathwayBrowser/#/R-MMU-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Mus musculus 57836 R-MMU-9606894 https://reactome.org/PathwayBrowser/#/R-MMU-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Mus musculus 57836 R-MMU-9632858 https://reactome.org/PathwayBrowser/#/R-MMU-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Mus musculus 57836 R-MMU-9632906 https://reactome.org/PathwayBrowser/#/R-MMU-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Mus musculus 57836 R-MMU-9632910 https://reactome.org/PathwayBrowser/#/R-MMU-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Mus musculus 57836 R-MMU-9632918 https://reactome.org/PathwayBrowser/#/R-MMU-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Mus musculus 57836 R-MMU-9647619 https://reactome.org/PathwayBrowser/#/R-MMU-9647619 GSDMD forms ring‐shaped oligomers IEA Mus musculus 57836 R-MMU-9647631 https://reactome.org/PathwayBrowser/#/R-MMU-9647631 GSDMD (1-275) binds PIPs IEA Mus musculus 57836 R-MMU-9647645 https://reactome.org/PathwayBrowser/#/R-MMU-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Mus musculus 57836 R-MMU-9647660 https://reactome.org/PathwayBrowser/#/R-MMU-9647660 GSDME (1-270) binds PIPs IEA Mus musculus 57836 R-MMU-9682182 https://reactome.org/PathwayBrowser/#/R-MMU-9682182 Csf1r-associated PI3K phosphorylates phosphatidylinositol 4,5-bisphosphate TAS Mus musculus 57836 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus 57836 R-MMU-9700149 https://reactome.org/PathwayBrowser/#/R-MMU-9700149 Active ALK binds PLCG1 IEA Mus musculus 57836 R-MMU-9700171 https://reactome.org/PathwayBrowser/#/R-MMU-9700171 Active ALK phosphorylates PLCG1 IEA Mus musculus 57836 R-MMU-9710254 https://reactome.org/PathwayBrowser/#/R-MMU-9710254 GSDME oligomerizes IEA Mus musculus 57836 R-NUL-9616944 https://reactome.org/PathwayBrowser/#/R-NUL-9616944 Activated Ntrk3 stimulates PI3K activity TAS Mus musculus 57836 R-NUL-9620024 https://reactome.org/PathwayBrowser/#/R-NUL-9620024 PDPK1 phosphorylates Rps6ka2 TAS Homo sapiens 57836 R-PFA-109701 https://reactome.org/PathwayBrowser/#/R-PFA-109701 PDPK1 binds PIP3 IEA Plasmodium falciparum 57836 R-PFA-1675773 https://reactome.org/PathwayBrowser/#/R-PFA-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Plasmodium falciparum 57836 R-PFA-1675949 https://reactome.org/PathwayBrowser/#/R-PFA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Plasmodium falciparum 57836 R-PFA-202164 https://reactome.org/PathwayBrowser/#/R-PFA-202164 Translocation of PDK1 to Plasma membrane IEA Plasmodium falciparum 57836 R-PFA-2316429 https://reactome.org/PathwayBrowser/#/R-PFA-2316429 PIP3 recruits PDPK1 to the membrane IEA Plasmodium falciparum 57836 R-PFA-8849969 https://reactome.org/PathwayBrowser/#/R-PFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Plasmodium falciparum 57836 R-PFA-9606884 https://reactome.org/PathwayBrowser/#/R-PFA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Plasmodium falciparum 57836 R-PFA-9606894 https://reactome.org/PathwayBrowser/#/R-PFA-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Plasmodium falciparum 57836 R-RNO-109699 https://reactome.org/PathwayBrowser/#/R-RNO-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-109700 https://reactome.org/PathwayBrowser/#/R-RNO-109700 AKT2 binds PIP3 IEA Rattus norvegicus 57836 R-RNO-109701 https://reactome.org/PathwayBrowser/#/R-RNO-109701 PDPK1 binds PIP3 IEA Rattus norvegicus 57836 R-RNO-109702 https://reactome.org/PathwayBrowser/#/R-RNO-109702 PDPK1 phosphorylates AKT2 IEA Rattus norvegicus 57836 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus 57836 R-RNO-1250370 https://reactome.org/PathwayBrowser/#/R-RNO-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Rattus norvegicus 57836 R-RNO-1250462 https://reactome.org/PathwayBrowser/#/R-RNO-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Rattus norvegicus 57836 R-RNO-1306957 https://reactome.org/PathwayBrowser/#/R-RNO-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Rattus norvegicus 57836 R-RNO-1306979 https://reactome.org/PathwayBrowser/#/R-RNO-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Rattus norvegicus 57836 R-RNO-1433415 https://reactome.org/PathwayBrowser/#/R-RNO-1433415 Activation of RAC1 IEA Rattus norvegicus 57836 R-RNO-1433514 https://reactome.org/PathwayBrowser/#/R-RNO-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Rattus norvegicus 57836 R-RNO-1433542 https://reactome.org/PathwayBrowser/#/R-RNO-1433542 Phosphorylation and activation of VAV1 IEA Rattus norvegicus 57836 R-RNO-165162 https://reactome.org/PathwayBrowser/#/R-RNO-165162 Phosphorylation of TSC2 by PKB IEA Rattus norvegicus 57836 R-RNO-165182 https://reactome.org/PathwayBrowser/#/R-RNO-165182 Phosphorylation of complexed TSC2 by PKB IEA Rattus norvegicus 57836 R-RNO-1675773 https://reactome.org/PathwayBrowser/#/R-RNO-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Rattus norvegicus 57836 R-RNO-1675949 https://reactome.org/PathwayBrowser/#/R-RNO-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Rattus norvegicus 57836 R-RNO-1676048 https://reactome.org/PathwayBrowser/#/R-RNO-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Rattus norvegicus 57836 R-RNO-177923 https://reactome.org/PathwayBrowser/#/R-RNO-177923 Sustained activation of SRC kinase by SHP2 IEA Rattus norvegicus 57836 R-RNO-177924 https://reactome.org/PathwayBrowser/#/R-RNO-177924 Dephosphorylation of Gab1 by SHP2 IEA Rattus norvegicus 57836 R-RNO-177926 https://reactome.org/PathwayBrowser/#/R-RNO-177926 Dephosphorylation of PAG by SHP2 IEA Rattus norvegicus 57836 R-RNO-177927 https://reactome.org/PathwayBrowser/#/R-RNO-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Rattus norvegicus 57836 R-RNO-177930 https://reactome.org/PathwayBrowser/#/R-RNO-177930 GAB1 phosphorylation by EGFR kinase IEA Rattus norvegicus 57836 R-RNO-177935 https://reactome.org/PathwayBrowser/#/R-RNO-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Rattus norvegicus 57836 R-RNO-177939 https://reactome.org/PathwayBrowser/#/R-RNO-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Rattus norvegicus 57836 R-RNO-177941 https://reactome.org/PathwayBrowser/#/R-RNO-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Rattus norvegicus 57836 R-RNO-177944 https://reactome.org/PathwayBrowser/#/R-RNO-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Rattus norvegicus 57836 R-RNO-179467 https://reactome.org/PathwayBrowser/#/R-RNO-179467 GAB1 binds phosphatidylinositol-3,4,5-trisphosphate IEA Rattus norvegicus 57836 R-RNO-186800 https://reactome.org/PathwayBrowser/#/R-RNO-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-198266 https://reactome.org/PathwayBrowser/#/R-RNO-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Rattus norvegicus 57836 R-RNO-198640 https://reactome.org/PathwayBrowser/#/R-RNO-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Rattus norvegicus 57836 R-RNO-199443 https://reactome.org/PathwayBrowser/#/R-RNO-199443 THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation IEA Rattus norvegicus 57836 R-RNO-199456 https://reactome.org/PathwayBrowser/#/R-RNO-199456 PTEN dephosphorylates PIP3 IEA Rattus norvegicus 57836 R-RNO-201510 https://reactome.org/PathwayBrowser/#/R-RNO-201510 PI3K synthesizes PIP3 downstream of ALK IEA Rattus norvegicus 57836 R-RNO-202164 https://reactome.org/PathwayBrowser/#/R-RNO-202164 Translocation of PDK1 to Plasma membrane IEA Rattus norvegicus 57836 R-RNO-202222 https://reactome.org/PathwayBrowser/#/R-RNO-202222 Phosphorylation of PKC theta IEA Rattus norvegicus 57836 R-RNO-202237 https://reactome.org/PathwayBrowser/#/R-RNO-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Rattus norvegicus 57836 R-RNO-202365 https://reactome.org/PathwayBrowser/#/R-RNO-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-202394 https://reactome.org/PathwayBrowser/#/R-RNO-202394 Translocation of CARMA1 to Plasma membrane IEA Rattus norvegicus 57836 R-RNO-202437 https://reactome.org/PathwayBrowser/#/R-RNO-202437 Phosphorylation of CARMA1 IEA Rattus norvegicus 57836 R-RNO-202443 https://reactome.org/PathwayBrowser/#/R-RNO-202443 Oligomerization of CARMA1 IEA Rattus norvegicus 57836 R-RNO-202459 https://reactome.org/PathwayBrowser/#/R-RNO-202459 Phosphorylation of Bcl10 IEA Rattus norvegicus 57836 R-RNO-202466 https://reactome.org/PathwayBrowser/#/R-RNO-202466 Interaction of Bcl10 to CARMA1 IEA Rattus norvegicus 57836 R-RNO-202472 https://reactome.org/PathwayBrowser/#/R-RNO-202472 Translocation of TRAF6 to CBM complex IEA Rattus norvegicus 57836 R-RNO-202478 https://reactome.org/PathwayBrowser/#/R-RNO-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Rattus norvegicus 57836 R-RNO-202489 https://reactome.org/PathwayBrowser/#/R-RNO-202489 Oligomerization of Bcl10 IEA Rattus norvegicus 57836 R-RNO-202500 https://reactome.org/PathwayBrowser/#/R-RNO-202500 Activation of IKK complex IEA Rattus norvegicus 57836 R-RNO-202510 https://reactome.org/PathwayBrowser/#/R-RNO-202510 Activation of TAK1-TAB2 complex IEA Rattus norvegicus 57836 R-RNO-202692 https://reactome.org/PathwayBrowser/#/R-RNO-202692 PIP3 binds to RhoA and activates it IEA Rattus norvegicus 57836 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus 57836 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus 57836 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus 57836 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus 57836 R-RNO-2029465 https://reactome.org/PathwayBrowser/#/R-RNO-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Rattus norvegicus 57836 R-RNO-2029466 https://reactome.org/PathwayBrowser/#/R-RNO-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Rattus norvegicus 57836 R-RNO-2029469 https://reactome.org/PathwayBrowser/#/R-RNO-2029469 p-ERK phosphorylates WAVEs and ABI IEA Rattus norvegicus 57836 R-RNO-2045911 https://reactome.org/PathwayBrowser/#/R-RNO-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Rattus norvegicus 57836 R-RNO-2076220 https://reactome.org/PathwayBrowser/#/R-RNO-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Rattus norvegicus 57836 R-RNO-2130194 https://reactome.org/PathwayBrowser/#/R-RNO-2130194 ABL phosphorylates WAVEs IEA Rattus norvegicus 57836 R-RNO-2197690 https://reactome.org/PathwayBrowser/#/R-RNO-2197690 Detachment of WASP/WAVE IEA Rattus norvegicus 57836 R-RNO-2316429 https://reactome.org/PathwayBrowser/#/R-RNO-2316429 PIP3 recruits PDPK1 to the membrane IEA Rattus norvegicus 57836 R-RNO-2316434 https://reactome.org/PathwayBrowser/#/R-RNO-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-2317314 https://reactome.org/PathwayBrowser/#/R-RNO-2317314 AKT binds PDPK1 IEA Rattus norvegicus 57836 R-RNO-2317332 https://reactome.org/PathwayBrowser/#/R-RNO-2317332 PIP3 recruits AKT to the membrane IEA Rattus norvegicus 57836 R-RNO-2424476 https://reactome.org/PathwayBrowser/#/R-RNO-2424476 Activation of RAC1 by VAV2/3 IEA Rattus norvegicus 57836 R-RNO-2424480 https://reactome.org/PathwayBrowser/#/R-RNO-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-2424481 https://reactome.org/PathwayBrowser/#/R-RNO-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Rattus norvegicus 57836 R-RNO-2424484 https://reactome.org/PathwayBrowser/#/R-RNO-2424484 Phosphorylation of BTK by p-SYK IEA Rattus norvegicus 57836 R-RNO-2424485 https://reactome.org/PathwayBrowser/#/R-RNO-2424485 Release of p-PLCG1 IEA Rattus norvegicus 57836 R-RNO-2424486 https://reactome.org/PathwayBrowser/#/R-RNO-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Rattus norvegicus 57836 R-RNO-2424487 https://reactome.org/PathwayBrowser/#/R-RNO-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Rattus norvegicus 57836 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus 57836 R-RNO-2730840 https://reactome.org/PathwayBrowser/#/R-RNO-2730840 Activation of RAC1 by VAV IEA Rattus norvegicus 57836 R-RNO-2730841 https://reactome.org/PathwayBrowser/#/R-RNO-2730841 Phosphorylation and activation of VAV IEA Rattus norvegicus 57836 R-RNO-2730842 https://reactome.org/PathwayBrowser/#/R-RNO-2730842 PI3K associates with phosphorylated GAB2 IEA Rattus norvegicus 57836 R-RNO-2730847 https://reactome.org/PathwayBrowser/#/R-RNO-2730847 Hydrolysis of PIP2 by PLCG IEA Rattus norvegicus 57836 R-RNO-2730856 https://reactome.org/PathwayBrowser/#/R-RNO-2730856 Autophosphorylation of PAK IEA Rattus norvegicus 57836 R-RNO-2730858 https://reactome.org/PathwayBrowser/#/R-RNO-2730858 Autophosphorylation of BTK/ITK IEA Rattus norvegicus 57836 R-RNO-2730870 https://reactome.org/PathwayBrowser/#/R-RNO-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Rattus norvegicus 57836 R-RNO-2730889 https://reactome.org/PathwayBrowser/#/R-RNO-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Rattus norvegicus 57836 R-RNO-389158 https://reactome.org/PathwayBrowser/#/R-RNO-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-389348 https://reactome.org/PathwayBrowser/#/R-RNO-389348 Activation of Rac1 by pVav1 IEA Rattus norvegicus 57836 R-RNO-389350 https://reactome.org/PathwayBrowser/#/R-RNO-389350 Activation of Cdc42 by pVav1 IEA Rattus norvegicus 57836 R-RNO-389352 https://reactome.org/PathwayBrowser/#/R-RNO-389352 Translocation of Vav1 to CD28 IEA Rattus norvegicus 57836 R-RNO-389354 https://reactome.org/PathwayBrowser/#/R-RNO-389354 Activation of Vav1 IEA Rattus norvegicus 57836 R-RNO-392300 https://reactome.org/PathwayBrowser/#/R-RNO-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-437162 https://reactome.org/PathwayBrowser/#/R-RNO-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-437185 https://reactome.org/PathwayBrowser/#/R-RNO-437185 PDK1 activates PKC zeta TAS Rattus norvegicus 57836 R-RNO-437189 https://reactome.org/PathwayBrowser/#/R-RNO-437189 PDK1 binds PKC zeta TAS Rattus norvegicus 57836 R-RNO-442273 https://reactome.org/PathwayBrowser/#/R-RNO-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Rattus norvegicus 57836 R-RNO-449058 https://reactome.org/PathwayBrowser/#/R-RNO-449058 Interleukin-1 family are secreted IEA Rattus norvegicus 57836 R-RNO-5218819 https://reactome.org/PathwayBrowser/#/R-RNO-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-5218820 https://reactome.org/PathwayBrowser/#/R-RNO-5218820 Src kinases phosphorylate VAV IEA Rattus norvegicus 57836 R-RNO-5218850 https://reactome.org/PathwayBrowser/#/R-RNO-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 57836 R-RNO-5357445 https://reactome.org/PathwayBrowser/#/R-RNO-5357445 PAK1-3 dimer disassociates IEA Rattus norvegicus 57836 R-RNO-5357472 https://reactome.org/PathwayBrowser/#/R-RNO-5357472 PAK1-3 autophosphorylates IEA Rattus norvegicus 57836 R-RNO-5357483 https://reactome.org/PathwayBrowser/#/R-RNO-5357483 RAC1 binds PAK1-3 IEA Rattus norvegicus 57836 R-RNO-5620975 https://reactome.org/PathwayBrowser/#/R-RNO-5620975 MLKL binds PIPs IEA Rattus norvegicus 57836 R-RNO-5623632 https://reactome.org/PathwayBrowser/#/R-RNO-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Rattus norvegicus 57836 R-RNO-5623667 https://reactome.org/PathwayBrowser/#/R-RNO-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Rattus norvegicus 57836 R-RNO-5654147 https://reactome.org/PathwayBrowser/#/R-RNO-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Rattus norvegicus 57836 R-RNO-5654149 https://reactome.org/PathwayBrowser/#/R-RNO-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Rattus norvegicus 57836 R-RNO-5654151 https://reactome.org/PathwayBrowser/#/R-RNO-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Rattus norvegicus 57836 R-RNO-5654159 https://reactome.org/PathwayBrowser/#/R-RNO-5654159 Activated FGFR2 binds PLCG1 IEA Rattus norvegicus 57836 R-RNO-5654163 https://reactome.org/PathwayBrowser/#/R-RNO-5654163 Activated FGFR4 binds PLCG1 IEA Rattus norvegicus 57836 R-RNO-5654167 https://reactome.org/PathwayBrowser/#/R-RNO-5654167 Activated FGFR1 binds PLCG1 IEA Rattus norvegicus 57836 R-RNO-5654222 https://reactome.org/PathwayBrowser/#/R-RNO-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Rattus norvegicus 57836 R-RNO-5654224 https://reactome.org/PathwayBrowser/#/R-RNO-5654224 Activated FGFR3 binds PLCG1 IEA Rattus norvegicus 57836 R-RNO-5654690 https://reactome.org/PathwayBrowser/#/R-RNO-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-5654692 https://reactome.org/PathwayBrowser/#/R-RNO-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-5654697 https://reactome.org/PathwayBrowser/#/R-RNO-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-5654701 https://reactome.org/PathwayBrowser/#/R-RNO-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-5654705 https://reactome.org/PathwayBrowser/#/R-RNO-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-5654709 https://reactome.org/PathwayBrowser/#/R-RNO-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-5654714 https://reactome.org/PathwayBrowser/#/R-RNO-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-5654717 https://reactome.org/PathwayBrowser/#/R-RNO-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-6795473 https://reactome.org/PathwayBrowser/#/R-RNO-6795473 PDPK1 phosphorylates SGK1 IEA Rattus norvegicus 57836 R-RNO-6805981 https://reactome.org/PathwayBrowser/#/R-RNO-6805981 HMGB1 release from cells IEA Rattus norvegicus 57836 R-RNO-8849969 https://reactome.org/PathwayBrowser/#/R-RNO-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Rattus norvegicus 57836 R-RNO-8852019 https://reactome.org/PathwayBrowser/#/R-RNO-8852019 MET bound PI3K generates PIP3 IEA Rattus norvegicus 57836 R-RNO-8874470 https://reactome.org/PathwayBrowser/#/R-RNO-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Rattus norvegicus 57836 R-RNO-8951586 https://reactome.org/PathwayBrowser/#/R-RNO-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Rattus norvegicus 57836 R-RNO-9021627 https://reactome.org/PathwayBrowser/#/R-RNO-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 57836 R-RNO-917693 https://reactome.org/PathwayBrowser/#/R-RNO-917693 ESCRT Disassembly IEA Rattus norvegicus 57836 R-RNO-917696 https://reactome.org/PathwayBrowser/#/R-RNO-917696 Cargo Sequestration IEA Rattus norvegicus 57836 R-RNO-917700 https://reactome.org/PathwayBrowser/#/R-RNO-917700 MVB Vesicle Formation IEA Rattus norvegicus 57836 R-RNO-917730 https://reactome.org/PathwayBrowser/#/R-RNO-917730 Cargo Recognition And Sorting IEA Rattus norvegicus 57836 R-RNO-9603279 https://reactome.org/PathwayBrowser/#/R-RNO-9603279 PIP3 recruits PDK1 and AKT to the membrane IEA Rattus norvegicus 57836 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus 57836 R-RNO-9606884 https://reactome.org/PathwayBrowser/#/R-RNO-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Rattus norvegicus 57836 R-RNO-9606894 https://reactome.org/PathwayBrowser/#/R-RNO-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Rattus norvegicus 57836 R-RNO-9632858 https://reactome.org/PathwayBrowser/#/R-RNO-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Rattus norvegicus 57836 R-RNO-9632906 https://reactome.org/PathwayBrowser/#/R-RNO-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Rattus norvegicus 57836 R-RNO-9632910 https://reactome.org/PathwayBrowser/#/R-RNO-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Rattus norvegicus 57836 R-RNO-9632918 https://reactome.org/PathwayBrowser/#/R-RNO-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Rattus norvegicus 57836 R-RNO-9647619 https://reactome.org/PathwayBrowser/#/R-RNO-9647619 GSDMD forms ring‐shaped oligomers IEA Rattus norvegicus 57836 R-RNO-9647631 https://reactome.org/PathwayBrowser/#/R-RNO-9647631 GSDMD (1-275) binds PIPs IEA Rattus norvegicus 57836 R-RNO-9647645 https://reactome.org/PathwayBrowser/#/R-RNO-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Rattus norvegicus 57836 R-RNO-9647660 https://reactome.org/PathwayBrowser/#/R-RNO-9647660 GSDME (1-270) binds PIPs IEA Rattus norvegicus 57836 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus 57836 R-RNO-9700149 https://reactome.org/PathwayBrowser/#/R-RNO-9700149 Active ALK binds PLCG1 IEA Rattus norvegicus 57836 R-RNO-9700171 https://reactome.org/PathwayBrowser/#/R-RNO-9700171 Active ALK phosphorylates PLCG1 IEA Rattus norvegicus 57836 R-RNO-9710254 https://reactome.org/PathwayBrowser/#/R-RNO-9710254 GSDME oligomerizes IEA Rattus norvegicus 57836 R-SCE-109701 https://reactome.org/PathwayBrowser/#/R-SCE-109701 PDPK1 binds PIP3 IEA Saccharomyces cerevisiae 57836 R-SCE-109702 https://reactome.org/PathwayBrowser/#/R-SCE-109702 PDPK1 phosphorylates AKT2 IEA Saccharomyces cerevisiae 57836 R-SCE-1675773 https://reactome.org/PathwayBrowser/#/R-SCE-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Saccharomyces cerevisiae 57836 R-SCE-1675949 https://reactome.org/PathwayBrowser/#/R-SCE-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Saccharomyces cerevisiae 57836 R-SCE-198640 https://reactome.org/PathwayBrowser/#/R-SCE-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Saccharomyces cerevisiae 57836 R-SCE-199456 https://reactome.org/PathwayBrowser/#/R-SCE-199456 PTEN dephosphorylates PIP3 IEA Saccharomyces cerevisiae 57836 R-SCE-202164 https://reactome.org/PathwayBrowser/#/R-SCE-202164 Translocation of PDK1 to Plasma membrane IEA Saccharomyces cerevisiae 57836 R-SCE-202222 https://reactome.org/PathwayBrowser/#/R-SCE-202222 Phosphorylation of PKC theta IEA Saccharomyces cerevisiae 57836 R-SCE-202692 https://reactome.org/PathwayBrowser/#/R-SCE-202692 PIP3 binds to RhoA and activates it IEA Saccharomyces cerevisiae 57836 R-SCE-2316429 https://reactome.org/PathwayBrowser/#/R-SCE-2316429 PIP3 recruits PDPK1 to the membrane IEA Saccharomyces cerevisiae 57836 R-SCE-2317314 https://reactome.org/PathwayBrowser/#/R-SCE-2317314 AKT binds PDPK1 IEA Saccharomyces cerevisiae 57836 R-SCE-2317332 https://reactome.org/PathwayBrowser/#/R-SCE-2317332 PIP3 recruits AKT to the membrane IEA Saccharomyces cerevisiae 57836 R-SCE-5623632 https://reactome.org/PathwayBrowser/#/R-SCE-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Saccharomyces cerevisiae 57836 R-SCE-5623667 https://reactome.org/PathwayBrowser/#/R-SCE-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Saccharomyces cerevisiae 57836 R-SCE-6795473 https://reactome.org/PathwayBrowser/#/R-SCE-6795473 PDPK1 phosphorylates SGK1 IEA Saccharomyces cerevisiae 57836 R-SCE-917693 https://reactome.org/PathwayBrowser/#/R-SCE-917693 ESCRT Disassembly IEA Saccharomyces cerevisiae 57836 R-SCE-917696 https://reactome.org/PathwayBrowser/#/R-SCE-917696 Cargo Sequestration IEA Saccharomyces cerevisiae 57836 R-SCE-917700 https://reactome.org/PathwayBrowser/#/R-SCE-917700 MVB Vesicle Formation IEA Saccharomyces cerevisiae 57836 R-SCE-9603279 https://reactome.org/PathwayBrowser/#/R-SCE-9603279 PIP3 recruits PDK1 and AKT to the membrane IEA Saccharomyces cerevisiae 57836 R-SCE-9606884 https://reactome.org/PathwayBrowser/#/R-SCE-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Saccharomyces cerevisiae 57836 R-SCE-9606894 https://reactome.org/PathwayBrowser/#/R-SCE-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Saccharomyces cerevisiae 57836 R-SCE-9632858 https://reactome.org/PathwayBrowser/#/R-SCE-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Saccharomyces cerevisiae 57836 R-SPO-109701 https://reactome.org/PathwayBrowser/#/R-SPO-109701 PDPK1 binds PIP3 IEA Schizosaccharomyces pombe 57836 R-SPO-109702 https://reactome.org/PathwayBrowser/#/R-SPO-109702 PDPK1 phosphorylates AKT2 IEA Schizosaccharomyces pombe 57836 R-SPO-165162 https://reactome.org/PathwayBrowser/#/R-SPO-165162 Phosphorylation of TSC2 by PKB IEA Schizosaccharomyces pombe 57836 R-SPO-165182 https://reactome.org/PathwayBrowser/#/R-SPO-165182 Phosphorylation of complexed TSC2 by PKB IEA Schizosaccharomyces pombe 57836 R-SPO-1675773 https://reactome.org/PathwayBrowser/#/R-SPO-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Schizosaccharomyces pombe 57836 R-SPO-198640 https://reactome.org/PathwayBrowser/#/R-SPO-198640 TORC2 (mTOR) phosphorylates AKT at S473 IEA Schizosaccharomyces pombe 57836 R-SPO-199456 https://reactome.org/PathwayBrowser/#/R-SPO-199456 PTEN dephosphorylates PIP3 IEA Schizosaccharomyces pombe 57836 R-SPO-202164 https://reactome.org/PathwayBrowser/#/R-SPO-202164 Translocation of PDK1 to Plasma membrane IEA Schizosaccharomyces pombe 57836 R-SPO-202222 https://reactome.org/PathwayBrowser/#/R-SPO-202222 Phosphorylation of PKC theta IEA Schizosaccharomyces pombe 57836 R-SPO-202692 https://reactome.org/PathwayBrowser/#/R-SPO-202692 PIP3 binds to RhoA and activates it IEA Schizosaccharomyces pombe 57836 R-SPO-2316429 https://reactome.org/PathwayBrowser/#/R-SPO-2316429 PIP3 recruits PDPK1 to the membrane IEA Schizosaccharomyces pombe 57836 R-SPO-2317314 https://reactome.org/PathwayBrowser/#/R-SPO-2317314 AKT binds PDPK1 IEA Schizosaccharomyces pombe 57836 R-SPO-2317332 https://reactome.org/PathwayBrowser/#/R-SPO-2317332 PIP3 recruits AKT to the membrane IEA Schizosaccharomyces pombe 57836 R-SPO-5623632 https://reactome.org/PathwayBrowser/#/R-SPO-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Schizosaccharomyces pombe 57836 R-SPO-5623667 https://reactome.org/PathwayBrowser/#/R-SPO-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Schizosaccharomyces pombe 57836 R-SPO-6795473 https://reactome.org/PathwayBrowser/#/R-SPO-6795473 PDPK1 phosphorylates SGK1 IEA Schizosaccharomyces pombe 57836 R-SPO-917693 https://reactome.org/PathwayBrowser/#/R-SPO-917693 ESCRT Disassembly IEA Schizosaccharomyces pombe 57836 R-SPO-917700 https://reactome.org/PathwayBrowser/#/R-SPO-917700 MVB Vesicle Formation IEA Schizosaccharomyces pombe 57836 R-SPO-9603279 https://reactome.org/PathwayBrowser/#/R-SPO-9603279 PIP3 recruits PDK1 and AKT to the membrane IEA Schizosaccharomyces pombe 57836 R-SPO-9606884 https://reactome.org/PathwayBrowser/#/R-SPO-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Schizosaccharomyces pombe 57836 R-SPO-9606894 https://reactome.org/PathwayBrowser/#/R-SPO-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Schizosaccharomyces pombe 57836 R-SPO-9632858 https://reactome.org/PathwayBrowser/#/R-SPO-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Schizosaccharomyces pombe 57836 R-SSC-109699 https://reactome.org/PathwayBrowser/#/R-SSC-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-109700 https://reactome.org/PathwayBrowser/#/R-SSC-109700 AKT2 binds PIP3 IEA Sus scrofa 57836 R-SSC-109701 https://reactome.org/PathwayBrowser/#/R-SSC-109701 PDPK1 binds PIP3 IEA Sus scrofa 57836 R-SSC-109702 https://reactome.org/PathwayBrowser/#/R-SSC-109702 PDPK1 phosphorylates AKT2 IEA Sus scrofa 57836 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa 57836 R-SSC-1250370 https://reactome.org/PathwayBrowser/#/R-SSC-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Sus scrofa 57836 R-SSC-1250462 https://reactome.org/PathwayBrowser/#/R-SSC-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Sus scrofa 57836 R-SSC-1306957 https://reactome.org/PathwayBrowser/#/R-SSC-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Sus scrofa 57836 R-SSC-1306979 https://reactome.org/PathwayBrowser/#/R-SSC-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Sus scrofa 57836 R-SSC-1433415 https://reactome.org/PathwayBrowser/#/R-SSC-1433415 Activation of RAC1 IEA Sus scrofa 57836 R-SSC-1433514 https://reactome.org/PathwayBrowser/#/R-SSC-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Sus scrofa 57836 R-SSC-1433542 https://reactome.org/PathwayBrowser/#/R-SSC-1433542 Phosphorylation and activation of VAV1 IEA Sus scrofa 57836 R-SSC-165162 https://reactome.org/PathwayBrowser/#/R-SSC-165162 Phosphorylation of TSC2 by PKB IEA Sus scrofa 57836 R-SSC-165182 https://reactome.org/PathwayBrowser/#/R-SSC-165182 Phosphorylation of complexed TSC2 by PKB IEA Sus scrofa 57836 R-SSC-1675773 https://reactome.org/PathwayBrowser/#/R-SSC-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Sus scrofa 57836 R-SSC-1675949 https://reactome.org/PathwayBrowser/#/R-SSC-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Sus scrofa 57836 R-SSC-1676048 https://reactome.org/PathwayBrowser/#/R-SSC-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Sus scrofa 57836 R-SSC-177923 https://reactome.org/PathwayBrowser/#/R-SSC-177923 Sustained activation of SRC kinase by SHP2 IEA Sus scrofa 57836 R-SSC-177924 https://reactome.org/PathwayBrowser/#/R-SSC-177924 Dephosphorylation of Gab1 by SHP2 IEA Sus scrofa 57836 R-SSC-177926 https://reactome.org/PathwayBrowser/#/R-SSC-177926 Dephosphorylation of PAG by SHP2 IEA Sus scrofa 57836 R-SSC-177927 https://reactome.org/PathwayBrowser/#/R-SSC-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Sus scrofa 57836 R-SSC-177930 https://reactome.org/PathwayBrowser/#/R-SSC-177930 GAB1 phosphorylation by EGFR kinase IEA Sus scrofa 57836 R-SSC-177935 https://reactome.org/PathwayBrowser/#/R-SSC-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Sus scrofa 57836 R-SSC-177939 https://reactome.org/PathwayBrowser/#/R-SSC-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Sus scrofa 57836 R-SSC-177941 https://reactome.org/PathwayBrowser/#/R-SSC-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Sus scrofa 57836 R-SSC-177944 https://reactome.org/PathwayBrowser/#/R-SSC-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Sus scrofa 57836 R-SSC-179467 https://reactome.org/PathwayBrowser/#/R-SSC-179467 GAB1 binds phosphatidylinositol-3,4,5-trisphosphate IEA Sus scrofa 57836 R-SSC-186800 https://reactome.org/PathwayBrowser/#/R-SSC-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-198266 https://reactome.org/PathwayBrowser/#/R-SSC-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Sus scrofa 57836 R-SSC-199456 https://reactome.org/PathwayBrowser/#/R-SSC-199456 PTEN dephosphorylates PIP3 IEA Sus scrofa 57836 R-SSC-201510 https://reactome.org/PathwayBrowser/#/R-SSC-201510 PI3K synthesizes PIP3 downstream of ALK IEA Sus scrofa 57836 R-SSC-202164 https://reactome.org/PathwayBrowser/#/R-SSC-202164 Translocation of PDK1 to Plasma membrane IEA Sus scrofa 57836 R-SSC-202222 https://reactome.org/PathwayBrowser/#/R-SSC-202222 Phosphorylation of PKC theta IEA Sus scrofa 57836 R-SSC-202237 https://reactome.org/PathwayBrowser/#/R-SSC-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Sus scrofa 57836 R-SSC-202365 https://reactome.org/PathwayBrowser/#/R-SSC-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-202394 https://reactome.org/PathwayBrowser/#/R-SSC-202394 Translocation of CARMA1 to Plasma membrane IEA Sus scrofa 57836 R-SSC-202437 https://reactome.org/PathwayBrowser/#/R-SSC-202437 Phosphorylation of CARMA1 IEA Sus scrofa 57836 R-SSC-202443 https://reactome.org/PathwayBrowser/#/R-SSC-202443 Oligomerization of CARMA1 IEA Sus scrofa 57836 R-SSC-202453 https://reactome.org/PathwayBrowser/#/R-SSC-202453 Auto-ubiquitination of TRAF6 IEA Sus scrofa 57836 R-SSC-202459 https://reactome.org/PathwayBrowser/#/R-SSC-202459 Phosphorylation of Bcl10 IEA Sus scrofa 57836 R-SSC-202466 https://reactome.org/PathwayBrowser/#/R-SSC-202466 Interaction of Bcl10 to CARMA1 IEA Sus scrofa 57836 R-SSC-202472 https://reactome.org/PathwayBrowser/#/R-SSC-202472 Translocation of TRAF6 to CBM complex IEA Sus scrofa 57836 R-SSC-202478 https://reactome.org/PathwayBrowser/#/R-SSC-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Sus scrofa 57836 R-SSC-202489 https://reactome.org/PathwayBrowser/#/R-SSC-202489 Oligomerization of Bcl10 IEA Sus scrofa 57836 R-SSC-202500 https://reactome.org/PathwayBrowser/#/R-SSC-202500 Activation of IKK complex IEA Sus scrofa 57836 R-SSC-202510 https://reactome.org/PathwayBrowser/#/R-SSC-202510 Activation of TAK1-TAB2 complex IEA Sus scrofa 57836 R-SSC-202534 https://reactome.org/PathwayBrowser/#/R-SSC-202534 Ubiquitination of NEMO by TRAF6 IEA Sus scrofa 57836 R-SSC-202692 https://reactome.org/PathwayBrowser/#/R-SSC-202692 PIP3 binds to RhoA and activates it IEA Sus scrofa 57836 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa 57836 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa 57836 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa 57836 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa 57836 R-SSC-2029465 https://reactome.org/PathwayBrowser/#/R-SSC-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Sus scrofa 57836 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa 57836 R-SSC-2029469 https://reactome.org/PathwayBrowser/#/R-SSC-2029469 p-ERK phosphorylates WAVEs and ABI IEA Sus scrofa 57836 R-SSC-2045911 https://reactome.org/PathwayBrowser/#/R-SSC-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Sus scrofa 57836 R-SSC-2076220 https://reactome.org/PathwayBrowser/#/R-SSC-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Sus scrofa 57836 R-SSC-2130194 https://reactome.org/PathwayBrowser/#/R-SSC-2130194 ABL phosphorylates WAVEs IEA Sus scrofa 57836 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa 57836 R-SSC-2316429 https://reactome.org/PathwayBrowser/#/R-SSC-2316429 PIP3 recruits PDPK1 to the membrane IEA Sus scrofa 57836 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-2424476 https://reactome.org/PathwayBrowser/#/R-SSC-2424476 Activation of RAC1 by VAV2/3 IEA Sus scrofa 57836 R-SSC-2424480 https://reactome.org/PathwayBrowser/#/R-SSC-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-2424481 https://reactome.org/PathwayBrowser/#/R-SSC-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Sus scrofa 57836 R-SSC-2424484 https://reactome.org/PathwayBrowser/#/R-SSC-2424484 Phosphorylation of BTK by p-SYK IEA Sus scrofa 57836 R-SSC-2424485 https://reactome.org/PathwayBrowser/#/R-SSC-2424485 Release of p-PLCG1 IEA Sus scrofa 57836 R-SSC-2424486 https://reactome.org/PathwayBrowser/#/R-SSC-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Sus scrofa 57836 R-SSC-2424487 https://reactome.org/PathwayBrowser/#/R-SSC-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Sus scrofa 57836 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa 57836 R-SSC-2730840 https://reactome.org/PathwayBrowser/#/R-SSC-2730840 Activation of RAC1 by VAV IEA Sus scrofa 57836 R-SSC-2730841 https://reactome.org/PathwayBrowser/#/R-SSC-2730841 Phosphorylation and activation of VAV IEA Sus scrofa 57836 R-SSC-2730842 https://reactome.org/PathwayBrowser/#/R-SSC-2730842 PI3K associates with phosphorylated GAB2 IEA Sus scrofa 57836 R-SSC-2730847 https://reactome.org/PathwayBrowser/#/R-SSC-2730847 Hydrolysis of PIP2 by PLCG IEA Sus scrofa 57836 R-SSC-2730856 https://reactome.org/PathwayBrowser/#/R-SSC-2730856 Autophosphorylation of PAK IEA Sus scrofa 57836 R-SSC-2730858 https://reactome.org/PathwayBrowser/#/R-SSC-2730858 Autophosphorylation of BTK/ITK IEA Sus scrofa 57836 R-SSC-2730870 https://reactome.org/PathwayBrowser/#/R-SSC-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Sus scrofa 57836 R-SSC-2730889 https://reactome.org/PathwayBrowser/#/R-SSC-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Sus scrofa 57836 R-SSC-389158 https://reactome.org/PathwayBrowser/#/R-SSC-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-389348 https://reactome.org/PathwayBrowser/#/R-SSC-389348 Activation of Rac1 by pVav1 IEA Sus scrofa 57836 R-SSC-389350 https://reactome.org/PathwayBrowser/#/R-SSC-389350 Activation of Cdc42 by pVav1 IEA Sus scrofa 57836 R-SSC-389352 https://reactome.org/PathwayBrowser/#/R-SSC-389352 Translocation of Vav1 to CD28 IEA Sus scrofa 57836 R-SSC-389354 https://reactome.org/PathwayBrowser/#/R-SSC-389354 Activation of Vav1 IEA Sus scrofa 57836 R-SSC-392300 https://reactome.org/PathwayBrowser/#/R-SSC-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-437162 https://reactome.org/PathwayBrowser/#/R-SSC-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-442273 https://reactome.org/PathwayBrowser/#/R-SSC-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Sus scrofa 57836 R-SSC-449058 https://reactome.org/PathwayBrowser/#/R-SSC-449058 Interleukin-1 family are secreted IEA Sus scrofa 57836 R-SSC-5218819 https://reactome.org/PathwayBrowser/#/R-SSC-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-5218820 https://reactome.org/PathwayBrowser/#/R-SSC-5218820 Src kinases phosphorylate VAV IEA Sus scrofa 57836 R-SSC-5218850 https://reactome.org/PathwayBrowser/#/R-SSC-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa 57836 R-SSC-5357445 https://reactome.org/PathwayBrowser/#/R-SSC-5357445 PAK1-3 dimer disassociates IEA Sus scrofa 57836 R-SSC-5357472 https://reactome.org/PathwayBrowser/#/R-SSC-5357472 PAK1-3 autophosphorylates IEA Sus scrofa 57836 R-SSC-5357483 https://reactome.org/PathwayBrowser/#/R-SSC-5357483 RAC1 binds PAK1-3 IEA Sus scrofa 57836 R-SSC-5620975 https://reactome.org/PathwayBrowser/#/R-SSC-5620975 MLKL binds PIPs IEA Sus scrofa 57836 R-SSC-5623632 https://reactome.org/PathwayBrowser/#/R-SSC-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Sus scrofa 57836 R-SSC-5623667 https://reactome.org/PathwayBrowser/#/R-SSC-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Sus scrofa 57836 R-SSC-5654149 https://reactome.org/PathwayBrowser/#/R-SSC-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Sus scrofa 57836 R-SSC-5654151 https://reactome.org/PathwayBrowser/#/R-SSC-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Sus scrofa 57836 R-SSC-5654163 https://reactome.org/PathwayBrowser/#/R-SSC-5654163 Activated FGFR4 binds PLCG1 IEA Sus scrofa 57836 R-SSC-5654167 https://reactome.org/PathwayBrowser/#/R-SSC-5654167 Activated FGFR1 binds PLCG1 IEA Sus scrofa 57836 R-SSC-5654690 https://reactome.org/PathwayBrowser/#/R-SSC-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-5654692 https://reactome.org/PathwayBrowser/#/R-SSC-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-5654697 https://reactome.org/PathwayBrowser/#/R-SSC-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-5654701 https://reactome.org/PathwayBrowser/#/R-SSC-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-5654705 https://reactome.org/PathwayBrowser/#/R-SSC-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-5654709 https://reactome.org/PathwayBrowser/#/R-SSC-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-5654714 https://reactome.org/PathwayBrowser/#/R-SSC-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-5654717 https://reactome.org/PathwayBrowser/#/R-SSC-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-6795473 https://reactome.org/PathwayBrowser/#/R-SSC-6795473 PDPK1 phosphorylates SGK1 IEA Sus scrofa 57836 R-SSC-8849969 https://reactome.org/PathwayBrowser/#/R-SSC-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Sus scrofa 57836 R-SSC-8852019 https://reactome.org/PathwayBrowser/#/R-SSC-8852019 MET bound PI3K generates PIP3 IEA Sus scrofa 57836 R-SSC-8874470 https://reactome.org/PathwayBrowser/#/R-SSC-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Sus scrofa 57836 R-SSC-8951586 https://reactome.org/PathwayBrowser/#/R-SSC-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Sus scrofa 57836 R-SSC-8964241 https://reactome.org/PathwayBrowser/#/R-SSC-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Sus scrofa 57836 R-SSC-8964271 https://reactome.org/PathwayBrowser/#/R-SSC-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Sus scrofa 57836 R-SSC-8964317 https://reactome.org/PathwayBrowser/#/R-SSC-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Sus scrofa 57836 R-SSC-9021627 https://reactome.org/PathwayBrowser/#/R-SSC-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 57836 R-SSC-917693 https://reactome.org/PathwayBrowser/#/R-SSC-917693 ESCRT Disassembly IEA Sus scrofa 57836 R-SSC-917696 https://reactome.org/PathwayBrowser/#/R-SSC-917696 Cargo Sequestration IEA Sus scrofa 57836 R-SSC-917700 https://reactome.org/PathwayBrowser/#/R-SSC-917700 MVB Vesicle Formation IEA Sus scrofa 57836 R-SSC-917730 https://reactome.org/PathwayBrowser/#/R-SSC-917730 Cargo Recognition And Sorting IEA Sus scrofa 57836 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa 57836 R-SSC-9606884 https://reactome.org/PathwayBrowser/#/R-SSC-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Sus scrofa 57836 R-SSC-9606894 https://reactome.org/PathwayBrowser/#/R-SSC-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Sus scrofa 57836 R-SSC-9632858 https://reactome.org/PathwayBrowser/#/R-SSC-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Sus scrofa 57836 R-SSC-9632906 https://reactome.org/PathwayBrowser/#/R-SSC-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Sus scrofa 57836 R-SSC-9632910 https://reactome.org/PathwayBrowser/#/R-SSC-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Sus scrofa 57836 R-SSC-9632918 https://reactome.org/PathwayBrowser/#/R-SSC-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Sus scrofa 57836 R-SSC-9647619 https://reactome.org/PathwayBrowser/#/R-SSC-9647619 GSDMD forms ring‐shaped oligomers IEA Sus scrofa 57836 R-SSC-9647631 https://reactome.org/PathwayBrowser/#/R-SSC-9647631 GSDMD (1-275) binds PIPs IEA Sus scrofa 57836 R-SSC-9647645 https://reactome.org/PathwayBrowser/#/R-SSC-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Sus scrofa 57836 R-SSC-9647660 https://reactome.org/PathwayBrowser/#/R-SSC-9647660 GSDME (1-270) binds PIPs IEA Sus scrofa 57836 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa 57836 R-SSC-9700149 https://reactome.org/PathwayBrowser/#/R-SSC-9700149 Active ALK binds PLCG1 IEA Sus scrofa 57836 R-SSC-9700171 https://reactome.org/PathwayBrowser/#/R-SSC-9700171 Active ALK phosphorylates PLCG1 IEA Sus scrofa 57836 R-SSC-9710254 https://reactome.org/PathwayBrowser/#/R-SSC-9710254 GSDME oligomerizes IEA Sus scrofa 57836 R-XTR-109699 https://reactome.org/PathwayBrowser/#/R-XTR-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-109701 https://reactome.org/PathwayBrowser/#/R-XTR-109701 PDPK1 binds PIP3 IEA Xenopus tropicalis 57836 R-XTR-1250370 https://reactome.org/PathwayBrowser/#/R-XTR-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Xenopus tropicalis 57836 R-XTR-1306957 https://reactome.org/PathwayBrowser/#/R-XTR-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Xenopus tropicalis 57836 R-XTR-1306979 https://reactome.org/PathwayBrowser/#/R-XTR-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Xenopus tropicalis 57836 R-XTR-1433415 https://reactome.org/PathwayBrowser/#/R-XTR-1433415 Activation of RAC1 IEA Xenopus tropicalis 57836 R-XTR-1433514 https://reactome.org/PathwayBrowser/#/R-XTR-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Xenopus tropicalis 57836 R-XTR-1433542 https://reactome.org/PathwayBrowser/#/R-XTR-1433542 Phosphorylation and activation of VAV1 IEA Xenopus tropicalis 57836 R-XTR-1675773 https://reactome.org/PathwayBrowser/#/R-XTR-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Xenopus tropicalis 57836 R-XTR-1675949 https://reactome.org/PathwayBrowser/#/R-XTR-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Xenopus tropicalis 57836 R-XTR-1676048 https://reactome.org/PathwayBrowser/#/R-XTR-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Xenopus tropicalis 57836 R-XTR-177924 https://reactome.org/PathwayBrowser/#/R-XTR-177924 Dephosphorylation of Gab1 by SHP2 IEA Xenopus tropicalis 57836 R-XTR-177926 https://reactome.org/PathwayBrowser/#/R-XTR-177926 Dephosphorylation of PAG by SHP2 IEA Xenopus tropicalis 57836 R-XTR-177927 https://reactome.org/PathwayBrowser/#/R-XTR-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Xenopus tropicalis 57836 R-XTR-177930 https://reactome.org/PathwayBrowser/#/R-XTR-177930 GAB1 phosphorylation by EGFR kinase IEA Xenopus tropicalis 57836 R-XTR-177935 https://reactome.org/PathwayBrowser/#/R-XTR-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Xenopus tropicalis 57836 R-XTR-177939 https://reactome.org/PathwayBrowser/#/R-XTR-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Xenopus tropicalis 57836 R-XTR-177941 https://reactome.org/PathwayBrowser/#/R-XTR-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Xenopus tropicalis 57836 R-XTR-177944 https://reactome.org/PathwayBrowser/#/R-XTR-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Xenopus tropicalis 57836 R-XTR-179467 https://reactome.org/PathwayBrowser/#/R-XTR-179467 GAB1 binds phosphatidylinositol-3,4,5-trisphosphate IEA Xenopus tropicalis 57836 R-XTR-186800 https://reactome.org/PathwayBrowser/#/R-XTR-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-198266 https://reactome.org/PathwayBrowser/#/R-XTR-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Xenopus tropicalis 57836 R-XTR-199456 https://reactome.org/PathwayBrowser/#/R-XTR-199456 PTEN dephosphorylates PIP3 IEA Xenopus tropicalis 57836 R-XTR-201510 https://reactome.org/PathwayBrowser/#/R-XTR-201510 PI3K synthesizes PIP3 downstream of ALK IEA Xenopus tropicalis 57836 R-XTR-202164 https://reactome.org/PathwayBrowser/#/R-XTR-202164 Translocation of PDK1 to Plasma membrane IEA Xenopus tropicalis 57836 R-XTR-202237 https://reactome.org/PathwayBrowser/#/R-XTR-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Xenopus tropicalis 57836 R-XTR-202394 https://reactome.org/PathwayBrowser/#/R-XTR-202394 Translocation of CARMA1 to Plasma membrane IEA Xenopus tropicalis 57836 R-XTR-202443 https://reactome.org/PathwayBrowser/#/R-XTR-202443 Oligomerization of CARMA1 IEA Xenopus tropicalis 57836 R-XTR-202692 https://reactome.org/PathwayBrowser/#/R-XTR-202692 PIP3 binds to RhoA and activates it IEA Xenopus tropicalis 57836 R-XTR-2029466 https://reactome.org/PathwayBrowser/#/R-XTR-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Xenopus tropicalis 57836 R-XTR-2029469 https://reactome.org/PathwayBrowser/#/R-XTR-2029469 p-ERK phosphorylates WAVEs and ABI IEA Xenopus tropicalis 57836 R-XTR-2130194 https://reactome.org/PathwayBrowser/#/R-XTR-2130194 ABL phosphorylates WAVEs IEA Xenopus tropicalis 57836 R-XTR-2197690 https://reactome.org/PathwayBrowser/#/R-XTR-2197690 Detachment of WASP/WAVE IEA Xenopus tropicalis 57836 R-XTR-2316429 https://reactome.org/PathwayBrowser/#/R-XTR-2316429 PIP3 recruits PDPK1 to the membrane IEA Xenopus tropicalis 57836 R-XTR-2316434 https://reactome.org/PathwayBrowser/#/R-XTR-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-2424476 https://reactome.org/PathwayBrowser/#/R-XTR-2424476 Activation of RAC1 by VAV2/3 IEA Xenopus tropicalis 57836 R-XTR-2424481 https://reactome.org/PathwayBrowser/#/R-XTR-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Xenopus tropicalis 57836 R-XTR-2424485 https://reactome.org/PathwayBrowser/#/R-XTR-2424485 Release of p-PLCG1 IEA Xenopus tropicalis 57836 R-XTR-2424487 https://reactome.org/PathwayBrowser/#/R-XTR-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Xenopus tropicalis 57836 R-XTR-2730840 https://reactome.org/PathwayBrowser/#/R-XTR-2730840 Activation of RAC1 by VAV IEA Xenopus tropicalis 57836 R-XTR-2730841 https://reactome.org/PathwayBrowser/#/R-XTR-2730841 Phosphorylation and activation of VAV IEA Xenopus tropicalis 57836 R-XTR-2730842 https://reactome.org/PathwayBrowser/#/R-XTR-2730842 PI3K associates with phosphorylated GAB2 IEA Xenopus tropicalis 57836 R-XTR-2730847 https://reactome.org/PathwayBrowser/#/R-XTR-2730847 Hydrolysis of PIP2 by PLCG IEA Xenopus tropicalis 57836 R-XTR-2730856 https://reactome.org/PathwayBrowser/#/R-XTR-2730856 Autophosphorylation of PAK IEA Xenopus tropicalis 57836 R-XTR-2730858 https://reactome.org/PathwayBrowser/#/R-XTR-2730858 Autophosphorylation of BTK/ITK IEA Xenopus tropicalis 57836 R-XTR-2730870 https://reactome.org/PathwayBrowser/#/R-XTR-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Xenopus tropicalis 57836 R-XTR-2730889 https://reactome.org/PathwayBrowser/#/R-XTR-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Xenopus tropicalis 57836 R-XTR-389158 https://reactome.org/PathwayBrowser/#/R-XTR-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-389348 https://reactome.org/PathwayBrowser/#/R-XTR-389348 Activation of Rac1 by pVav1 IEA Xenopus tropicalis 57836 R-XTR-389350 https://reactome.org/PathwayBrowser/#/R-XTR-389350 Activation of Cdc42 by pVav1 IEA Xenopus tropicalis 57836 R-XTR-389352 https://reactome.org/PathwayBrowser/#/R-XTR-389352 Translocation of Vav1 to CD28 IEA Xenopus tropicalis 57836 R-XTR-389354 https://reactome.org/PathwayBrowser/#/R-XTR-389354 Activation of Vav1 IEA Xenopus tropicalis 57836 R-XTR-392300 https://reactome.org/PathwayBrowser/#/R-XTR-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-437162 https://reactome.org/PathwayBrowser/#/R-XTR-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-442273 https://reactome.org/PathwayBrowser/#/R-XTR-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Xenopus tropicalis 57836 R-XTR-5218819 https://reactome.org/PathwayBrowser/#/R-XTR-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-5218850 https://reactome.org/PathwayBrowser/#/R-XTR-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Xenopus tropicalis 57836 R-XTR-5357445 https://reactome.org/PathwayBrowser/#/R-XTR-5357445 PAK1-3 dimer disassociates IEA Xenopus tropicalis 57836 R-XTR-5357472 https://reactome.org/PathwayBrowser/#/R-XTR-5357472 PAK1-3 autophosphorylates IEA Xenopus tropicalis 57836 R-XTR-5357483 https://reactome.org/PathwayBrowser/#/R-XTR-5357483 RAC1 binds PAK1-3 IEA Xenopus tropicalis 57836 R-XTR-5623632 https://reactome.org/PathwayBrowser/#/R-XTR-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Xenopus tropicalis 57836 R-XTR-5623667 https://reactome.org/PathwayBrowser/#/R-XTR-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Xenopus tropicalis 57836 R-XTR-5654149 https://reactome.org/PathwayBrowser/#/R-XTR-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Xenopus tropicalis 57836 R-XTR-5654151 https://reactome.org/PathwayBrowser/#/R-XTR-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Xenopus tropicalis 57836 R-XTR-5654163 https://reactome.org/PathwayBrowser/#/R-XTR-5654163 Activated FGFR4 binds PLCG1 IEA Xenopus tropicalis 57836 R-XTR-5654167 https://reactome.org/PathwayBrowser/#/R-XTR-5654167 Activated FGFR1 binds PLCG1 IEA Xenopus tropicalis 57836 R-XTR-5654690 https://reactome.org/PathwayBrowser/#/R-XTR-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-5654692 https://reactome.org/PathwayBrowser/#/R-XTR-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-5654697 https://reactome.org/PathwayBrowser/#/R-XTR-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-5654701 https://reactome.org/PathwayBrowser/#/R-XTR-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-5654705 https://reactome.org/PathwayBrowser/#/R-XTR-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-5654709 https://reactome.org/PathwayBrowser/#/R-XTR-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-5654714 https://reactome.org/PathwayBrowser/#/R-XTR-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-5654717 https://reactome.org/PathwayBrowser/#/R-XTR-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-6805981 https://reactome.org/PathwayBrowser/#/R-XTR-6805981 HMGB1 release from cells IEA Xenopus tropicalis 57836 R-XTR-8849969 https://reactome.org/PathwayBrowser/#/R-XTR-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Xenopus tropicalis 57836 R-XTR-8852019 https://reactome.org/PathwayBrowser/#/R-XTR-8852019 MET bound PI3K generates PIP3 IEA Xenopus tropicalis 57836 R-XTR-8874470 https://reactome.org/PathwayBrowser/#/R-XTR-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Xenopus tropicalis 57836 R-XTR-8951586 https://reactome.org/PathwayBrowser/#/R-XTR-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Xenopus tropicalis 57836 R-XTR-8964241 https://reactome.org/PathwayBrowser/#/R-XTR-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Xenopus tropicalis 57836 R-XTR-8964271 https://reactome.org/PathwayBrowser/#/R-XTR-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Xenopus tropicalis 57836 R-XTR-8964317 https://reactome.org/PathwayBrowser/#/R-XTR-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Xenopus tropicalis 57836 R-XTR-9021627 https://reactome.org/PathwayBrowser/#/R-XTR-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 57836 R-XTR-917693 https://reactome.org/PathwayBrowser/#/R-XTR-917693 ESCRT Disassembly IEA Xenopus tropicalis 57836 R-XTR-9606884 https://reactome.org/PathwayBrowser/#/R-XTR-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Xenopus tropicalis 57836 R-XTR-9606894 https://reactome.org/PathwayBrowser/#/R-XTR-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Xenopus tropicalis 57836 R-XTR-9647660 https://reactome.org/PathwayBrowser/#/R-XTR-9647660 GSDME (1-270) binds PIPs IEA Xenopus tropicalis 57836 R-XTR-9710254 https://reactome.org/PathwayBrowser/#/R-XTR-9710254 GSDME oligomerizes IEA Xenopus tropicalis 57844 R-BTA-1614654 https://reactome.org/PathwayBrowser/#/R-BTA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Bos taurus 57844 R-BTA-174374 https://reactome.org/PathwayBrowser/#/R-BTA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Bos taurus 57844 R-BTA-174391 https://reactome.org/PathwayBrowser/#/R-BTA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Bos taurus 57844 R-BTA-2534096 https://reactome.org/PathwayBrowser/#/R-BTA-2534096 METAP1/2 demethylates GNAT1 IEA Bos taurus 57844 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 57844 R-BTA-352103 https://reactome.org/PathwayBrowser/#/R-BTA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Bos taurus 57844 R-BTA-352107 https://reactome.org/PathwayBrowser/#/R-BTA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Bos taurus 57844 R-BTA-352108 https://reactome.org/PathwayBrowser/#/R-BTA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Bos taurus 57844 R-BTA-352119 https://reactome.org/PathwayBrowser/#/R-BTA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Bos taurus 57844 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 57844 R-BTA-352232 https://reactome.org/PathwayBrowser/#/R-BTA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Bos taurus 57844 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 57844 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 57844 R-BTA-5603114 https://reactome.org/PathwayBrowser/#/R-BTA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Bos taurus 57844 R-BTA-5676917 https://reactome.org/PathwayBrowser/#/R-BTA-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Bos taurus 57844 R-BTA-5676940 https://reactome.org/PathwayBrowser/#/R-BTA-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Bos taurus 57844 R-BTA-5696838 https://reactome.org/PathwayBrowser/#/R-BTA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Bos taurus 57844 R-BTA-6793591 https://reactome.org/PathwayBrowser/#/R-BTA-6793591 LIAS synthesizes lipoyl-GCSH IEA Bos taurus 57844 R-BTA-947535 https://reactome.org/PathwayBrowser/#/R-BTA-947535 Cyclisation of GTP to precursor Z IEA Bos taurus 57844 R-CEL-174374 https://reactome.org/PathwayBrowser/#/R-CEL-174374 MTR transfers CH3 from MeCbl to HCYS IEA Caenorhabditis elegans 57844 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 57844 R-CEL-5676917 https://reactome.org/PathwayBrowser/#/R-CEL-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Caenorhabditis elegans 57844 R-CEL-947535 https://reactome.org/PathwayBrowser/#/R-CEL-947535 Cyclisation of GTP to precursor Z IEA Caenorhabditis elegans 57844 R-CFA-1614654 https://reactome.org/PathwayBrowser/#/R-CFA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Canis familiaris 57844 R-CFA-174374 https://reactome.org/PathwayBrowser/#/R-CFA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Canis familiaris 57844 R-CFA-174391 https://reactome.org/PathwayBrowser/#/R-CFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Canis familiaris 57844 R-CFA-2534096 https://reactome.org/PathwayBrowser/#/R-CFA-2534096 METAP1/2 demethylates GNAT1 IEA Canis familiaris 57844 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 57844 R-CFA-352103 https://reactome.org/PathwayBrowser/#/R-CFA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Canis familiaris 57844 R-CFA-352107 https://reactome.org/PathwayBrowser/#/R-CFA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Canis familiaris 57844 R-CFA-352108 https://reactome.org/PathwayBrowser/#/R-CFA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Canis familiaris 57844 R-CFA-352119 https://reactome.org/PathwayBrowser/#/R-CFA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Canis familiaris 57844 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 57844 R-CFA-352232 https://reactome.org/PathwayBrowser/#/R-CFA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Canis familiaris 57844 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 57844 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 57844 R-CFA-5603114 https://reactome.org/PathwayBrowser/#/R-CFA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Canis familiaris 57844 R-CFA-5676917 https://reactome.org/PathwayBrowser/#/R-CFA-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Canis familiaris 57844 R-CFA-5676940 https://reactome.org/PathwayBrowser/#/R-CFA-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Canis familiaris 57844 R-CFA-5696838 https://reactome.org/PathwayBrowser/#/R-CFA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Canis familiaris 57844 R-CFA-6793591 https://reactome.org/PathwayBrowser/#/R-CFA-6793591 LIAS synthesizes lipoyl-GCSH IEA Canis familiaris 57844 R-CFA-947535 https://reactome.org/PathwayBrowser/#/R-CFA-947535 Cyclisation of GTP to precursor Z IEA Canis familiaris 57844 R-CFS-1237106 https://reactome.org/PathwayBrowser/#/R-CFS-1237106 Transamination of MOB to methionine TAS Crithidia fasciculata 57844 R-DDI-174374 https://reactome.org/PathwayBrowser/#/R-DDI-174374 MTR transfers CH3 from MeCbl to HCYS IEA Dictyostelium discoideum 57844 R-DDI-174391 https://reactome.org/PathwayBrowser/#/R-DDI-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Dictyostelium discoideum 57844 R-DDI-2534096 https://reactome.org/PathwayBrowser/#/R-DDI-2534096 METAP1/2 demethylates GNAT1 IEA Dictyostelium discoideum 57844 R-DDI-5603114 https://reactome.org/PathwayBrowser/#/R-DDI-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Dictyostelium discoideum 57844 R-DDI-947535 https://reactome.org/PathwayBrowser/#/R-DDI-947535 Cyclisation of GTP to precursor Z IEA Dictyostelium discoideum 57844 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 57844 R-DME-352108 https://reactome.org/PathwayBrowser/#/R-DME-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57844 R-DME-352119 https://reactome.org/PathwayBrowser/#/R-DME-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57844 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57844 R-DME-352232 https://reactome.org/PathwayBrowser/#/R-DME-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Drosophila melanogaster 57844 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57844 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57844 R-DME-5676917 https://reactome.org/PathwayBrowser/#/R-DME-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Drosophila melanogaster 57844 R-DME-6793591 https://reactome.org/PathwayBrowser/#/R-DME-6793591 LIAS synthesizes lipoyl-GCSH IEA Drosophila melanogaster 57844 R-DME-947535 https://reactome.org/PathwayBrowser/#/R-DME-947535 Cyclisation of GTP to precursor Z IEA Drosophila melanogaster 57844 R-DRE-1614654 https://reactome.org/PathwayBrowser/#/R-DRE-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Danio rerio 57844 R-DRE-174391 https://reactome.org/PathwayBrowser/#/R-DRE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Danio rerio 57844 R-DRE-2534096 https://reactome.org/PathwayBrowser/#/R-DRE-2534096 METAP1/2 demethylates GNAT1 IEA Danio rerio 57844 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 57844 R-DRE-352103 https://reactome.org/PathwayBrowser/#/R-DRE-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Danio rerio 57844 R-DRE-352108 https://reactome.org/PathwayBrowser/#/R-DRE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Danio rerio 57844 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 57844 R-DRE-5603114 https://reactome.org/PathwayBrowser/#/R-DRE-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Danio rerio 57844 R-DRE-5676917 https://reactome.org/PathwayBrowser/#/R-DRE-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Danio rerio 57844 R-DRE-5696838 https://reactome.org/PathwayBrowser/#/R-DRE-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Danio rerio 57844 R-DRE-6793591 https://reactome.org/PathwayBrowser/#/R-DRE-6793591 LIAS synthesizes lipoyl-GCSH IEA Danio rerio 57844 R-GGA-1614654 https://reactome.org/PathwayBrowser/#/R-GGA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Gallus gallus 57844 R-GGA-174374 https://reactome.org/PathwayBrowser/#/R-GGA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Gallus gallus 57844 R-GGA-174391 https://reactome.org/PathwayBrowser/#/R-GGA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Gallus gallus 57844 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 57844 R-GGA-352107 https://reactome.org/PathwayBrowser/#/R-GGA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Gallus gallus 57844 R-GGA-352108 https://reactome.org/PathwayBrowser/#/R-GGA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Gallus gallus 57844 R-GGA-352119 https://reactome.org/PathwayBrowser/#/R-GGA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Gallus gallus 57844 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 57844 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 57844 R-GGA-5603114 https://reactome.org/PathwayBrowser/#/R-GGA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Gallus gallus 57844 R-GGA-5676917 https://reactome.org/PathwayBrowser/#/R-GGA-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Gallus gallus 57844 R-GGA-5676940 https://reactome.org/PathwayBrowser/#/R-GGA-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Gallus gallus 57844 R-GGA-5696838 https://reactome.org/PathwayBrowser/#/R-GGA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Gallus gallus 57844 R-GGA-6793591 https://reactome.org/PathwayBrowser/#/R-GGA-6793591 LIAS synthesizes lipoyl-GCSH IEA Gallus gallus 57844 R-GGA-947535 https://reactome.org/PathwayBrowser/#/R-GGA-947535 Cyclisation of GTP to precursor Z IEA Gallus gallus 57844 R-HSA-1237102 https://reactome.org/PathwayBrowser/#/R-HSA-1237102 Transamination of MOB to methionine IEA Homo sapiens 57844 R-HSA-1614654 https://reactome.org/PathwayBrowser/#/R-HSA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY TAS Homo sapiens 57844 R-HSA-174374 https://reactome.org/PathwayBrowser/#/R-HSA-174374 MTR transfers CH3 from MeCbl to HCYS TAS Homo sapiens 57844 R-HSA-174391 https://reactome.org/PathwayBrowser/#/R-HSA-174391 MAT1A multimers transfer Ado from ATP to L-Met TAS Homo sapiens 57844 R-HSA-2534096 https://reactome.org/PathwayBrowser/#/R-HSA-2534096 METAP1/2 demethylates GNAT1 TAS Homo sapiens 57844 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 57844 R-HSA-352103 https://reactome.org/PathwayBrowser/#/R-HSA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids TAS Homo sapiens 57844 R-HSA-352107 https://reactome.org/PathwayBrowser/#/R-HSA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids TAS Homo sapiens 57844 R-HSA-352108 https://reactome.org/PathwayBrowser/#/R-HSA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids TAS Homo sapiens 57844 R-HSA-352119 https://reactome.org/PathwayBrowser/#/R-HSA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids TAS Homo sapiens 57844 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 57844 R-HSA-352232 https://reactome.org/PathwayBrowser/#/R-HSA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol TAS Homo sapiens 57844 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57844 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57844 R-HSA-379994 https://reactome.org/PathwayBrowser/#/R-HSA-379994 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 57844 R-HSA-380157 https://reactome.org/PathwayBrowser/#/R-HSA-380157 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate TAS Homo sapiens 57844 R-HSA-5603087 https://reactome.org/PathwayBrowser/#/R-HSA-5603087 Defective MAT1A does not transfer Ado from ATP to L-Met TAS Homo sapiens 57844 R-HSA-5603114 https://reactome.org/PathwayBrowser/#/R-HSA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met TAS Homo sapiens 57844 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57844 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57844 R-HSA-5676912 https://reactome.org/PathwayBrowser/#/R-HSA-5676912 Methionine is oxidised to methionine sulfoxide TAS Homo sapiens 57844 R-HSA-5676917 https://reactome.org/PathwayBrowser/#/R-HSA-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine TAS Homo sapiens 57844 R-HSA-5676940 https://reactome.org/PathwayBrowser/#/R-HSA-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine TAS Homo sapiens 57844 R-HSA-5696838 https://reactome.org/PathwayBrowser/#/R-HSA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS TAS Homo sapiens 57844 R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 57844 R-HSA-6793591 https://reactome.org/PathwayBrowser/#/R-HSA-6793591 LIAS synthesizes lipoyl-GCSH TAS Homo sapiens 57844 R-HSA-947535 https://reactome.org/PathwayBrowser/#/R-HSA-947535 Cyclisation of GTP to precursor Z TAS Homo sapiens 57844 R-MMU-1614654 https://reactome.org/PathwayBrowser/#/R-MMU-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Mus musculus 57844 R-MMU-174374 https://reactome.org/PathwayBrowser/#/R-MMU-174374 MTR transfers CH3 from MeCbl to HCYS IEA Mus musculus 57844 R-MMU-174391 https://reactome.org/PathwayBrowser/#/R-MMU-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Mus musculus 57844 R-MMU-2534096 https://reactome.org/PathwayBrowser/#/R-MMU-2534096 METAP1/2 demethylates GNAT1 IEA Mus musculus 57844 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 57844 R-MMU-352103 https://reactome.org/PathwayBrowser/#/R-MMU-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Mus musculus 57844 R-MMU-352107 https://reactome.org/PathwayBrowser/#/R-MMU-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Mus musculus 57844 R-MMU-352108 https://reactome.org/PathwayBrowser/#/R-MMU-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Mus musculus 57844 R-MMU-352119 https://reactome.org/PathwayBrowser/#/R-MMU-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Mus musculus 57844 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 57844 R-MMU-352232 https://reactome.org/PathwayBrowser/#/R-MMU-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Mus musculus 57844 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 57844 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 57844 R-MMU-5603114 https://reactome.org/PathwayBrowser/#/R-MMU-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Mus musculus 57844 R-MMU-5676917 https://reactome.org/PathwayBrowser/#/R-MMU-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Mus musculus 57844 R-MMU-5676940 https://reactome.org/PathwayBrowser/#/R-MMU-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Mus musculus 57844 R-MMU-5696838 https://reactome.org/PathwayBrowser/#/R-MMU-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Mus musculus 57844 R-MMU-6793591 https://reactome.org/PathwayBrowser/#/R-MMU-6793591 LIAS synthesizes lipoyl-GCSH IEA Mus musculus 57844 R-MMU-947535 https://reactome.org/PathwayBrowser/#/R-MMU-947535 Cyclisation of GTP to precursor Z IEA Mus musculus 57844 R-PFA-174391 https://reactome.org/PathwayBrowser/#/R-PFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Plasmodium falciparum 57844 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 57844 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57844 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57844 R-RNO-1614654 https://reactome.org/PathwayBrowser/#/R-RNO-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Rattus norvegicus 57844 R-RNO-174374 https://reactome.org/PathwayBrowser/#/R-RNO-174374 MTR transfers CH3 from MeCbl to HCYS IEA Rattus norvegicus 57844 R-RNO-174391 https://reactome.org/PathwayBrowser/#/R-RNO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Rattus norvegicus 57844 R-RNO-2534096 https://reactome.org/PathwayBrowser/#/R-RNO-2534096 METAP1/2 demethylates GNAT1 IEA Rattus norvegicus 57844 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 57844 R-RNO-352103 https://reactome.org/PathwayBrowser/#/R-RNO-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Rattus norvegicus 57844 R-RNO-352107 https://reactome.org/PathwayBrowser/#/R-RNO-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Rattus norvegicus 57844 R-RNO-352108 https://reactome.org/PathwayBrowser/#/R-RNO-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Rattus norvegicus 57844 R-RNO-352119 https://reactome.org/PathwayBrowser/#/R-RNO-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Rattus norvegicus 57844 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 57844 R-RNO-352232 https://reactome.org/PathwayBrowser/#/R-RNO-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Rattus norvegicus 57844 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 57844 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 57844 R-RNO-5603114 https://reactome.org/PathwayBrowser/#/R-RNO-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Rattus norvegicus 57844 R-RNO-5676917 https://reactome.org/PathwayBrowser/#/R-RNO-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Rattus norvegicus 57844 R-RNO-5676940 https://reactome.org/PathwayBrowser/#/R-RNO-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Rattus norvegicus 57844 R-RNO-5696838 https://reactome.org/PathwayBrowser/#/R-RNO-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Rattus norvegicus 57844 R-RNO-6793591 https://reactome.org/PathwayBrowser/#/R-RNO-6793591 LIAS synthesizes lipoyl-GCSH IEA Rattus norvegicus 57844 R-RNO-947535 https://reactome.org/PathwayBrowser/#/R-RNO-947535 Cyclisation of GTP to precursor Z IEA Rattus norvegicus 57844 R-SCE-174391 https://reactome.org/PathwayBrowser/#/R-SCE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Saccharomyces cerevisiae 57844 R-SCE-2534096 https://reactome.org/PathwayBrowser/#/R-SCE-2534096 METAP1/2 demethylates GNAT1 IEA Saccharomyces cerevisiae 57844 R-SCE-352108 https://reactome.org/PathwayBrowser/#/R-SCE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 57844 R-SCE-352119 https://reactome.org/PathwayBrowser/#/R-SCE-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 57844 R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 57844 R-SPO-174391 https://reactome.org/PathwayBrowser/#/R-SPO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Schizosaccharomyces pombe 57844 R-SPO-2534096 https://reactome.org/PathwayBrowser/#/R-SPO-2534096 METAP1/2 demethylates GNAT1 IEA Schizosaccharomyces pombe 57844 R-SSC-1614654 https://reactome.org/PathwayBrowser/#/R-SSC-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Sus scrofa 57844 R-SSC-174374 https://reactome.org/PathwayBrowser/#/R-SSC-174374 MTR transfers CH3 from MeCbl to HCYS IEA Sus scrofa 57844 R-SSC-174391 https://reactome.org/PathwayBrowser/#/R-SSC-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Sus scrofa 57844 R-SSC-2534096 https://reactome.org/PathwayBrowser/#/R-SSC-2534096 METAP1/2 demethylates GNAT1 IEA Sus scrofa 57844 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 57844 R-SSC-352103 https://reactome.org/PathwayBrowser/#/R-SSC-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Sus scrofa 57844 R-SSC-352107 https://reactome.org/PathwayBrowser/#/R-SSC-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Sus scrofa 57844 R-SSC-352108 https://reactome.org/PathwayBrowser/#/R-SSC-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Sus scrofa 57844 R-SSC-352119 https://reactome.org/PathwayBrowser/#/R-SSC-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Sus scrofa 57844 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 57844 R-SSC-352232 https://reactome.org/PathwayBrowser/#/R-SSC-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Sus scrofa 57844 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 57844 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 57844 R-SSC-5603114 https://reactome.org/PathwayBrowser/#/R-SSC-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Sus scrofa 57844 R-SSC-5676917 https://reactome.org/PathwayBrowser/#/R-SSC-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Sus scrofa 57844 R-SSC-5676940 https://reactome.org/PathwayBrowser/#/R-SSC-5676940 MSRA reduces L-methyl-(S)-S-oxide to L-Methionine IEA Sus scrofa 57844 R-SSC-5696838 https://reactome.org/PathwayBrowser/#/R-SSC-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Sus scrofa 57844 R-SSC-6793591 https://reactome.org/PathwayBrowser/#/R-SSC-6793591 LIAS synthesizes lipoyl-GCSH IEA Sus scrofa 57844 R-SSC-947535 https://reactome.org/PathwayBrowser/#/R-SSC-947535 Cyclisation of GTP to precursor Z IEA Sus scrofa 57844 R-XTR-1614654 https://reactome.org/PathwayBrowser/#/R-XTR-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Xenopus tropicalis 57844 R-XTR-174391 https://reactome.org/PathwayBrowser/#/R-XTR-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Xenopus tropicalis 57844 R-XTR-2534096 https://reactome.org/PathwayBrowser/#/R-XTR-2534096 METAP1/2 demethylates GNAT1 IEA Xenopus tropicalis 57844 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 57844 R-XTR-352103 https://reactome.org/PathwayBrowser/#/R-XTR-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Xenopus tropicalis 57844 R-XTR-352107 https://reactome.org/PathwayBrowser/#/R-XTR-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Xenopus tropicalis 57844 R-XTR-352108 https://reactome.org/PathwayBrowser/#/R-XTR-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57844 R-XTR-352119 https://reactome.org/PathwayBrowser/#/R-XTR-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57844 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57844 R-XTR-352232 https://reactome.org/PathwayBrowser/#/R-XTR-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Xenopus tropicalis 57844 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57844 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57844 R-XTR-5603114 https://reactome.org/PathwayBrowser/#/R-XTR-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Xenopus tropicalis 57844 R-XTR-5696838 https://reactome.org/PathwayBrowser/#/R-XTR-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Xenopus tropicalis 57844 R-XTR-947535 https://reactome.org/PathwayBrowser/#/R-XTR-947535 Cyclisation of GTP to precursor Z IEA Xenopus tropicalis 57845 R-BTA-189406 https://reactome.org/PathwayBrowser/#/R-BTA-189406 4 PBGs bind to form HMB IEA Bos taurus 57845 R-BTA-189488 https://reactome.org/PathwayBrowser/#/R-BTA-189488 UROS transforms HMB to URO3 IEA Bos taurus 57845 R-CFA-189406 https://reactome.org/PathwayBrowser/#/R-CFA-189406 4 PBGs bind to form HMB IEA Canis familiaris 57845 R-CFA-189488 https://reactome.org/PathwayBrowser/#/R-CFA-189488 UROS transforms HMB to URO3 IEA Canis familiaris 57845 R-DDI-189488 https://reactome.org/PathwayBrowser/#/R-DDI-189488 UROS transforms HMB to URO3 IEA Dictyostelium discoideum 57845 R-DME-189406 https://reactome.org/PathwayBrowser/#/R-DME-189406 4 PBGs bind to form HMB IEA Drosophila melanogaster 57845 R-DME-189488 https://reactome.org/PathwayBrowser/#/R-DME-189488 UROS transforms HMB to URO3 IEA Drosophila melanogaster 57845 R-DRE-189488 https://reactome.org/PathwayBrowser/#/R-DRE-189488 UROS transforms HMB to URO3 IEA Danio rerio 57845 R-GGA-189406 https://reactome.org/PathwayBrowser/#/R-GGA-189406 4 PBGs bind to form HMB IEA Gallus gallus 57845 R-GGA-189488 https://reactome.org/PathwayBrowser/#/R-GGA-189488 UROS transforms HMB to URO3 IEA Gallus gallus 57845 R-GGA-421439 https://reactome.org/PathwayBrowser/#/R-GGA-421439 4 porphobilinogen + H2O => hydroxymethylbilane + 4 NH3 IEA Gallus gallus 57845 R-GGA-421471 https://reactome.org/PathwayBrowser/#/R-GGA-421471 hydroxymethylbilane => uroporphyrinogen I + H2O IEA Gallus gallus 57845 R-GGA-421482 https://reactome.org/PathwayBrowser/#/R-GGA-421482 hydroxymethylbilane => uroporphyrinogen III + H2O IEA Gallus gallus 57845 R-HSA-189406 https://reactome.org/PathwayBrowser/#/R-HSA-189406 4 PBGs bind to form HMB TAS Homo sapiens 57845 R-HSA-189488 https://reactome.org/PathwayBrowser/#/R-HSA-189488 UROS transforms HMB to URO3 TAS Homo sapiens 57845 R-HSA-190168 https://reactome.org/PathwayBrowser/#/R-HSA-190168 HMBL spontaneously transforms to URO1 TAS Homo sapiens 57845 R-MMU-189406 https://reactome.org/PathwayBrowser/#/R-MMU-189406 4 PBGs bind to form HMB IEA Mus musculus 57845 R-MMU-189488 https://reactome.org/PathwayBrowser/#/R-MMU-189488 UROS transforms HMB to URO3 IEA Mus musculus 57845 R-PFA-189406 https://reactome.org/PathwayBrowser/#/R-PFA-189406 4 PBGs bind to form HMB IEA Plasmodium falciparum 57845 R-RNO-189406 https://reactome.org/PathwayBrowser/#/R-RNO-189406 4 PBGs bind to form HMB IEA Rattus norvegicus 57845 R-RNO-189488 https://reactome.org/PathwayBrowser/#/R-RNO-189488 UROS transforms HMB to URO3 IEA Rattus norvegicus 57845 R-SCE-189406 https://reactome.org/PathwayBrowser/#/R-SCE-189406 4 PBGs bind to form HMB IEA Saccharomyces cerevisiae 57845 R-SCE-189488 https://reactome.org/PathwayBrowser/#/R-SCE-189488 UROS transforms HMB to URO3 IEA Saccharomyces cerevisiae 57845 R-SPO-189406 https://reactome.org/PathwayBrowser/#/R-SPO-189406 4 PBGs bind to form HMB IEA Schizosaccharomyces pombe 57845 R-SPO-189488 https://reactome.org/PathwayBrowser/#/R-SPO-189488 UROS transforms HMB to URO3 IEA Schizosaccharomyces pombe 57845 R-SSC-189406 https://reactome.org/PathwayBrowser/#/R-SSC-189406 4 PBGs bind to form HMB IEA Sus scrofa 57845 R-SSC-189488 https://reactome.org/PathwayBrowser/#/R-SSC-189488 UROS transforms HMB to URO3 IEA Sus scrofa 57845 R-XTR-189406 https://reactome.org/PathwayBrowser/#/R-XTR-189406 4 PBGs bind to form HMB IEA Xenopus tropicalis 57845 R-XTR-189488 https://reactome.org/PathwayBrowser/#/R-XTR-189488 UROS transforms HMB to URO3 IEA Xenopus tropicalis 57847 R-BTA-1971482 https://reactome.org/PathwayBrowser/#/R-BTA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Bos taurus 57847 R-BTA-1971487 https://reactome.org/PathwayBrowser/#/R-BTA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Bos taurus 57847 R-BTA-735702 https://reactome.org/PathwayBrowser/#/R-BTA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Bos taurus 57847 R-BTA-8851619 https://reactome.org/PathwayBrowser/#/R-BTA-8851619 GALNT3 transfers GalNAc to FGF23 IEA Bos taurus 57847 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 57847 R-BTA-8931648 https://reactome.org/PathwayBrowser/#/R-BTA-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Bos taurus 57847 R-BTA-9033959 https://reactome.org/PathwayBrowser/#/R-BTA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Bos taurus 57847 R-BTA-9034042 https://reactome.org/PathwayBrowser/#/R-BTA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Bos taurus 57847 R-BTA-913675 https://reactome.org/PathwayBrowser/#/R-BTA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Bos taurus 57847 R-BTA-914017 https://reactome.org/PathwayBrowser/#/R-BTA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Bos taurus 57847 R-BTA-9605700 https://reactome.org/PathwayBrowser/#/R-BTA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Bos taurus 57847 R-BTA-9632033 https://reactome.org/PathwayBrowser/#/R-BTA-9632033 CHSY1 transfers GalNAc to chondroitin IEA Bos taurus 57847 R-CEL-735702 https://reactome.org/PathwayBrowser/#/R-CEL-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Caenorhabditis elegans 57847 R-CEL-913675 https://reactome.org/PathwayBrowser/#/R-CEL-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Caenorhabditis elegans 57847 R-CEL-914017 https://reactome.org/PathwayBrowser/#/R-CEL-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Caenorhabditis elegans 57847 R-CFA-1971482 https://reactome.org/PathwayBrowser/#/R-CFA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Canis familiaris 57847 R-CFA-1971487 https://reactome.org/PathwayBrowser/#/R-CFA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Canis familiaris 57847 R-CFA-735702 https://reactome.org/PathwayBrowser/#/R-CFA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Canis familiaris 57847 R-CFA-8851619 https://reactome.org/PathwayBrowser/#/R-CFA-8851619 GALNT3 transfers GalNAc to FGF23 IEA Canis familiaris 57847 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 57847 R-CFA-8878914 https://reactome.org/PathwayBrowser/#/R-CFA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Canis familiaris 57847 R-CFA-8931648 https://reactome.org/PathwayBrowser/#/R-CFA-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Canis familiaris 57847 R-CFA-9033959 https://reactome.org/PathwayBrowser/#/R-CFA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Canis familiaris 57847 R-CFA-9034042 https://reactome.org/PathwayBrowser/#/R-CFA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Canis familiaris 57847 R-CFA-913675 https://reactome.org/PathwayBrowser/#/R-CFA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Canis familiaris 57847 R-CFA-914017 https://reactome.org/PathwayBrowser/#/R-CFA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Canis familiaris 57847 R-CFA-9605700 https://reactome.org/PathwayBrowser/#/R-CFA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Canis familiaris 57847 R-CFA-9632033 https://reactome.org/PathwayBrowser/#/R-CFA-9632033 CHSY1 transfers GalNAc to chondroitin IEA Canis familiaris 57847 R-DDI-914017 https://reactome.org/PathwayBrowser/#/R-DDI-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Dictyostelium discoideum 57847 R-DME-1971482 https://reactome.org/PathwayBrowser/#/R-DME-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Drosophila melanogaster 57847 R-DME-1971487 https://reactome.org/PathwayBrowser/#/R-DME-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Drosophila melanogaster 57847 R-DME-735702 https://reactome.org/PathwayBrowser/#/R-DME-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Drosophila melanogaster 57847 R-DME-8851619 https://reactome.org/PathwayBrowser/#/R-DME-8851619 GALNT3 transfers GalNAc to FGF23 IEA Drosophila melanogaster 57847 R-DME-8878914 https://reactome.org/PathwayBrowser/#/R-DME-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Drosophila melanogaster 57847 R-DME-913675 https://reactome.org/PathwayBrowser/#/R-DME-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Drosophila melanogaster 57847 R-DME-914017 https://reactome.org/PathwayBrowser/#/R-DME-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Drosophila melanogaster 57847 R-DME-9632033 https://reactome.org/PathwayBrowser/#/R-DME-9632033 CHSY1 transfers GalNAc to chondroitin IEA Drosophila melanogaster 57847 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 57847 R-DRE-8931648 https://reactome.org/PathwayBrowser/#/R-DRE-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Danio rerio 57847 R-DRE-9033959 https://reactome.org/PathwayBrowser/#/R-DRE-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Danio rerio 57847 R-DRE-9034042 https://reactome.org/PathwayBrowser/#/R-DRE-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Danio rerio 57847 R-DRE-913675 https://reactome.org/PathwayBrowser/#/R-DRE-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Danio rerio 57847 R-DRE-914017 https://reactome.org/PathwayBrowser/#/R-DRE-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Danio rerio 57847 R-DRE-9632033 https://reactome.org/PathwayBrowser/#/R-DRE-9632033 CHSY1 transfers GalNAc to chondroitin IEA Danio rerio 57847 R-GGA-1971482 https://reactome.org/PathwayBrowser/#/R-GGA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Gallus gallus 57847 R-GGA-1971487 https://reactome.org/PathwayBrowser/#/R-GGA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Gallus gallus 57847 R-GGA-8851619 https://reactome.org/PathwayBrowser/#/R-GGA-8851619 GALNT3 transfers GalNAc to FGF23 IEA Gallus gallus 57847 R-GGA-8878914 https://reactome.org/PathwayBrowser/#/R-GGA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Gallus gallus 57847 R-GGA-8931648 https://reactome.org/PathwayBrowser/#/R-GGA-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Gallus gallus 57847 R-GGA-913675 https://reactome.org/PathwayBrowser/#/R-GGA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Gallus gallus 57847 R-GGA-914017 https://reactome.org/PathwayBrowser/#/R-GGA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Gallus gallus 57847 R-GGA-9632033 https://reactome.org/PathwayBrowser/#/R-GGA-9632033 CHSY1 transfers GalNAc to chondroitin IEA Gallus gallus 57847 R-HSA-1971482 https://reactome.org/PathwayBrowser/#/R-HSA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin TAS Homo sapiens 57847 R-HSA-1971487 https://reactome.org/PathwayBrowser/#/R-HSA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin TAS Homo sapiens 57847 R-HSA-3595176 https://reactome.org/PathwayBrowser/#/R-HSA-3595176 Defective CHSY1 does not transfer GalNAc to chondroitin TAS Homo sapiens 57847 R-HSA-5096532 https://reactome.org/PathwayBrowser/#/R-HSA-5096532 Defective GALNT12 does not transfer GalNAc to mucins TAS Homo sapiens 57847 R-HSA-5096537 https://reactome.org/PathwayBrowser/#/R-HSA-5096537 Defective GALNT3 does not transfer GalNAc to mucins TAS Homo sapiens 57847 R-HSA-5652099 https://reactome.org/PathwayBrowser/#/R-HSA-5652099 Defective SLC35A2 does not exchange UDP-Gal, UDP-GalNAc for UMP TAS Homo sapiens 57847 R-HSA-735702 https://reactome.org/PathwayBrowser/#/R-HSA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP TAS Homo sapiens 57847 R-HSA-8851619 https://reactome.org/PathwayBrowser/#/R-HSA-8851619 GALNT3 transfers GalNAc to FGF23 TAS Homo sapiens 57847 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 57847 R-HSA-8878914 https://reactome.org/PathwayBrowser/#/R-HSA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer TAS Homo sapiens 57847 R-HSA-8931648 https://reactome.org/PathwayBrowser/#/R-HSA-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 TAS Homo sapiens 57847 R-HSA-9033959 https://reactome.org/PathwayBrowser/#/R-HSA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC TAS Homo sapiens 57847 R-HSA-9034042 https://reactome.org/PathwayBrowser/#/R-HSA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec TAS Homo sapiens 57847 R-HSA-913675 https://reactome.org/PathwayBrowser/#/R-HSA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens TAS Homo sapiens 57847 R-HSA-914017 https://reactome.org/PathwayBrowser/#/R-HSA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein TAS Homo sapiens 57847 R-HSA-9605700 https://reactome.org/PathwayBrowser/#/R-HSA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda TAS Homo sapiens 57847 R-HSA-9632033 https://reactome.org/PathwayBrowser/#/R-HSA-9632033 CHSY1 transfers GalNAc to chondroitin TAS Homo sapiens 57847 R-MMU-1971482 https://reactome.org/PathwayBrowser/#/R-MMU-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Mus musculus 57847 R-MMU-1971487 https://reactome.org/PathwayBrowser/#/R-MMU-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Mus musculus 57847 R-MMU-735702 https://reactome.org/PathwayBrowser/#/R-MMU-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Mus musculus 57847 R-MMU-8851619 https://reactome.org/PathwayBrowser/#/R-MMU-8851619 GALNT3 transfers GalNAc to FGF23 IEA Mus musculus 57847 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 57847 R-MMU-8878914 https://reactome.org/PathwayBrowser/#/R-MMU-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Mus musculus 57847 R-MMU-8931648 https://reactome.org/PathwayBrowser/#/R-MMU-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Mus musculus 57847 R-MMU-9033959 https://reactome.org/PathwayBrowser/#/R-MMU-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Mus musculus 57847 R-MMU-9034042 https://reactome.org/PathwayBrowser/#/R-MMU-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Mus musculus 57847 R-MMU-913675 https://reactome.org/PathwayBrowser/#/R-MMU-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Mus musculus 57847 R-MMU-914017 https://reactome.org/PathwayBrowser/#/R-MMU-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Mus musculus 57847 R-MMU-9605700 https://reactome.org/PathwayBrowser/#/R-MMU-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Mus musculus 57847 R-MMU-9632033 https://reactome.org/PathwayBrowser/#/R-MMU-9632033 CHSY1 transfers GalNAc to chondroitin IEA Mus musculus 57847 R-PFA-735702 https://reactome.org/PathwayBrowser/#/R-PFA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Plasmodium falciparum 57847 R-PFA-914017 https://reactome.org/PathwayBrowser/#/R-PFA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Plasmodium falciparum 57847 R-RNO-1971482 https://reactome.org/PathwayBrowser/#/R-RNO-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Rattus norvegicus 57847 R-RNO-1971487 https://reactome.org/PathwayBrowser/#/R-RNO-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Rattus norvegicus 57847 R-RNO-735702 https://reactome.org/PathwayBrowser/#/R-RNO-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Rattus norvegicus 57847 R-RNO-8851619 https://reactome.org/PathwayBrowser/#/R-RNO-8851619 GALNT3 transfers GalNAc to FGF23 IEA Rattus norvegicus 57847 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 57847 R-RNO-8878914 https://reactome.org/PathwayBrowser/#/R-RNO-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Rattus norvegicus 57847 R-RNO-8931648 https://reactome.org/PathwayBrowser/#/R-RNO-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Rattus norvegicus 57847 R-RNO-9033959 https://reactome.org/PathwayBrowser/#/R-RNO-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Rattus norvegicus 57847 R-RNO-9034042 https://reactome.org/PathwayBrowser/#/R-RNO-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Rattus norvegicus 57847 R-RNO-913675 https://reactome.org/PathwayBrowser/#/R-RNO-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Rattus norvegicus 57847 R-RNO-914017 https://reactome.org/PathwayBrowser/#/R-RNO-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Rattus norvegicus 57847 R-RNO-9605700 https://reactome.org/PathwayBrowser/#/R-RNO-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Rattus norvegicus 57847 R-RNO-9632033 https://reactome.org/PathwayBrowser/#/R-RNO-9632033 CHSY1 transfers GalNAc to chondroitin IEA Rattus norvegicus 57847 R-SSC-1971482 https://reactome.org/PathwayBrowser/#/R-SSC-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Sus scrofa 57847 R-SSC-1971487 https://reactome.org/PathwayBrowser/#/R-SSC-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Sus scrofa 57847 R-SSC-735702 https://reactome.org/PathwayBrowser/#/R-SSC-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Sus scrofa 57847 R-SSC-8851619 https://reactome.org/PathwayBrowser/#/R-SSC-8851619 GALNT3 transfers GalNAc to FGF23 IEA Sus scrofa 57847 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 57847 R-SSC-8878914 https://reactome.org/PathwayBrowser/#/R-SSC-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Sus scrofa 57847 R-SSC-8931648 https://reactome.org/PathwayBrowser/#/R-SSC-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Sus scrofa 57847 R-SSC-913675 https://reactome.org/PathwayBrowser/#/R-SSC-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Sus scrofa 57847 R-SSC-914017 https://reactome.org/PathwayBrowser/#/R-SSC-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Sus scrofa 57847 R-SSC-9605700 https://reactome.org/PathwayBrowser/#/R-SSC-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Sus scrofa 57847 R-SSC-9632033 https://reactome.org/PathwayBrowser/#/R-SSC-9632033 CHSY1 transfers GalNAc to chondroitin IEA Sus scrofa 57847 R-XTR-1971482 https://reactome.org/PathwayBrowser/#/R-XTR-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Xenopus tropicalis 57847 R-XTR-1971487 https://reactome.org/PathwayBrowser/#/R-XTR-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Xenopus tropicalis 57847 R-XTR-8851619 https://reactome.org/PathwayBrowser/#/R-XTR-8851619 GALNT3 transfers GalNAc to FGF23 IEA Xenopus tropicalis 57847 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 57847 R-XTR-8931648 https://reactome.org/PathwayBrowser/#/R-XTR-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Xenopus tropicalis 57847 R-XTR-9033959 https://reactome.org/PathwayBrowser/#/R-XTR-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Xenopus tropicalis 57847 R-XTR-9034042 https://reactome.org/PathwayBrowser/#/R-XTR-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Xenopus tropicalis 57847 R-XTR-913675 https://reactome.org/PathwayBrowser/#/R-XTR-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Xenopus tropicalis 57847 R-XTR-914017 https://reactome.org/PathwayBrowser/#/R-XTR-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Xenopus tropicalis 57847 R-XTR-9605700 https://reactome.org/PathwayBrowser/#/R-XTR-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Xenopus tropicalis 57847 R-XTR-9632033 https://reactome.org/PathwayBrowser/#/R-XTR-9632033 CHSY1 transfers GalNAc to chondroitin IEA Xenopus tropicalis 57853 R-BTA-1655453 https://reactome.org/PathwayBrowser/#/R-BTA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Bos taurus 57853 R-BTA-6787757 https://reactome.org/PathwayBrowser/#/R-BTA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Bos taurus 57853 R-BTA-6814153 https://reactome.org/PathwayBrowser/#/R-BTA-6814153 ADO oxidises 2AET to HTAU IEA Bos taurus 57853 R-BTA-6814165 https://reactome.org/PathwayBrowser/#/R-BTA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Bos taurus 57853 R-CEL-1655453 https://reactome.org/PathwayBrowser/#/R-CEL-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Caenorhabditis elegans 57853 R-CEL-6814153 https://reactome.org/PathwayBrowser/#/R-CEL-6814153 ADO oxidises 2AET to HTAU IEA Caenorhabditis elegans 57853 R-CFA-1655453 https://reactome.org/PathwayBrowser/#/R-CFA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Canis familiaris 57853 R-CFA-6787757 https://reactome.org/PathwayBrowser/#/R-CFA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Canis familiaris 57853 R-CFA-6814153 https://reactome.org/PathwayBrowser/#/R-CFA-6814153 ADO oxidises 2AET to HTAU IEA Canis familiaris 57853 R-CFA-6814165 https://reactome.org/PathwayBrowser/#/R-CFA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Canis familiaris 57853 R-DDI-1655453 https://reactome.org/PathwayBrowser/#/R-DDI-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Dictyostelium discoideum 57853 R-DDI-6814153 https://reactome.org/PathwayBrowser/#/R-DDI-6814153 ADO oxidises 2AET to HTAU IEA Dictyostelium discoideum 57853 R-DME-6787757 https://reactome.org/PathwayBrowser/#/R-DME-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Drosophila melanogaster 57853 R-DME-6814153 https://reactome.org/PathwayBrowser/#/R-DME-6814153 ADO oxidises 2AET to HTAU IEA Drosophila melanogaster 57853 R-DME-6814165 https://reactome.org/PathwayBrowser/#/R-DME-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Drosophila melanogaster 57853 R-DRE-1655453 https://reactome.org/PathwayBrowser/#/R-DRE-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Danio rerio 57853 R-DRE-6814153 https://reactome.org/PathwayBrowser/#/R-DRE-6814153 ADO oxidises 2AET to HTAU IEA Danio rerio 57853 R-GGA-6787757 https://reactome.org/PathwayBrowser/#/R-GGA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Gallus gallus 57853 R-GGA-6814165 https://reactome.org/PathwayBrowser/#/R-GGA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Gallus gallus 57853 R-HSA-1655443 https://reactome.org/PathwayBrowser/#/R-HSA-1655443 PXKLP-K305-CSAD decarboxylates 3-sulfinoalanine to hypotaurine IEA Homo sapiens 57853 R-HSA-1655453 https://reactome.org/PathwayBrowser/#/R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU TAS Homo sapiens 57853 R-HSA-6787757 https://reactome.org/PathwayBrowser/#/R-HSA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs TAS Homo sapiens 57853 R-HSA-6814153 https://reactome.org/PathwayBrowser/#/R-HSA-6814153 ADO oxidises 2AET to HTAU TAS Homo sapiens 57853 R-HSA-6814165 https://reactome.org/PathwayBrowser/#/R-HSA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU TAS Homo sapiens 57853 R-MMU-1655453 https://reactome.org/PathwayBrowser/#/R-MMU-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Mus musculus 57853 R-MMU-6787757 https://reactome.org/PathwayBrowser/#/R-MMU-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Mus musculus 57853 R-MMU-6814153 https://reactome.org/PathwayBrowser/#/R-MMU-6814153 ADO oxidises 2AET to HTAU IEA Mus musculus 57853 R-MMU-6814165 https://reactome.org/PathwayBrowser/#/R-MMU-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Mus musculus 57853 R-RNO-1655440 https://reactome.org/PathwayBrowser/#/R-RNO-1655440 PXLP-K305-Csad decarboxylates 3-sulfinoalanine to hypotaurine TAS Rattus norvegicus 57853 R-RNO-1655453 https://reactome.org/PathwayBrowser/#/R-RNO-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Rattus norvegicus 57853 R-RNO-6787757 https://reactome.org/PathwayBrowser/#/R-RNO-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Rattus norvegicus 57853 R-RNO-6814153 https://reactome.org/PathwayBrowser/#/R-RNO-6814153 ADO oxidises 2AET to HTAU IEA Rattus norvegicus 57853 R-RNO-6814165 https://reactome.org/PathwayBrowser/#/R-RNO-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Rattus norvegicus 57853 R-SSC-1655453 https://reactome.org/PathwayBrowser/#/R-SSC-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Sus scrofa 57853 R-SSC-6787757 https://reactome.org/PathwayBrowser/#/R-SSC-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Sus scrofa 57853 R-SSC-6814153 https://reactome.org/PathwayBrowser/#/R-SSC-6814153 ADO oxidises 2AET to HTAU IEA Sus scrofa 57853 R-SSC-6814165 https://reactome.org/PathwayBrowser/#/R-SSC-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Sus scrofa 57853 R-XTR-1655453 https://reactome.org/PathwayBrowser/#/R-XTR-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Xenopus tropicalis 57853 R-XTR-6787757 https://reactome.org/PathwayBrowser/#/R-XTR-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Xenopus tropicalis 57853 R-XTR-6814153 https://reactome.org/PathwayBrowser/#/R-XTR-6814153 ADO oxidises 2AET to HTAU IEA Xenopus tropicalis 57853 R-XTR-6814165 https://reactome.org/PathwayBrowser/#/R-XTR-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Xenopus tropicalis 57856 R-BTA-1483174 https://reactome.org/PathwayBrowser/#/R-BTA-1483174 PE is methylated to PC by PEMT IEA Bos taurus 57856 R-BTA-158609 https://reactome.org/PathwayBrowser/#/R-BTA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Bos taurus 57856 R-BTA-174401 https://reactome.org/PathwayBrowser/#/R-BTA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Bos taurus 57856 R-BTA-175983 https://reactome.org/PathwayBrowser/#/R-BTA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Bos taurus 57856 R-BTA-175987 https://reactome.org/PathwayBrowser/#/R-BTA-175987 NNMT transfers CH3 from AdoMet to PY IEA Bos taurus 57856 R-BTA-209821 https://reactome.org/PathwayBrowser/#/R-BTA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Bos taurus 57856 R-BTA-209903 https://reactome.org/PathwayBrowser/#/R-BTA-209903 Noradrenaline is converted to adrenaline IEA Bos taurus 57856 R-BTA-212263 https://reactome.org/PathwayBrowser/#/R-BTA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Bos taurus 57856 R-BTA-212269 https://reactome.org/PathwayBrowser/#/R-BTA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Bos taurus 57856 R-BTA-2162186 https://reactome.org/PathwayBrowser/#/R-BTA-2162186 COQ3 methylates DeMQ10H2 IEA Bos taurus 57856 R-BTA-2162188 https://reactome.org/PathwayBrowser/#/R-BTA-2162188 COQ5 methylates MDMQ10H2 IEA Bos taurus 57856 R-BTA-2162193 https://reactome.org/PathwayBrowser/#/R-BTA-2162193 COQ3 methylates DHDB IEA Bos taurus 57856 R-BTA-2301205 https://reactome.org/PathwayBrowser/#/R-BTA-2301205 SETD8 monomethylates histone H4 IEA Bos taurus 57856 R-BTA-3149518 https://reactome.org/PathwayBrowser/#/R-BTA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Bos taurus 57856 R-BTA-3222237 https://reactome.org/PathwayBrowser/#/R-BTA-3222237 SMYD2 methylates TP53 IEA Bos taurus 57856 R-BTA-3240295 https://reactome.org/PathwayBrowser/#/R-BTA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Bos taurus 57856 R-BTA-3364026 https://reactome.org/PathwayBrowser/#/R-BTA-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Bos taurus 57856 R-BTA-3788745 https://reactome.org/PathwayBrowser/#/R-BTA-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Bos taurus 57856 R-BTA-3788748 https://reactome.org/PathwayBrowser/#/R-BTA-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Bos taurus 57856 R-BTA-379387 https://reactome.org/PathwayBrowser/#/R-BTA-379387 COMT transfers Met to DA to form 3MT IEA Bos taurus 57856 R-BTA-427527 https://reactome.org/PathwayBrowser/#/R-BTA-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Bos taurus 57856 R-BTA-4827382 https://reactome.org/PathwayBrowser/#/R-BTA-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Bos taurus 57856 R-BTA-4827383 https://reactome.org/PathwayBrowser/#/R-BTA-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Bos taurus 57856 R-BTA-5159245 https://reactome.org/PathwayBrowser/#/R-BTA-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Bos taurus 57856 R-BTA-5205798 https://reactome.org/PathwayBrowser/#/R-BTA-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Bos taurus 57856 R-BTA-5205799 https://reactome.org/PathwayBrowser/#/R-BTA-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Bos taurus 57856 R-BTA-5205820 https://reactome.org/PathwayBrowser/#/R-BTA-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Bos taurus 57856 R-BTA-5205822 https://reactome.org/PathwayBrowser/#/R-BTA-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 IEA Bos taurus 57856 R-BTA-5205824 https://reactome.org/PathwayBrowser/#/R-BTA-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Bos taurus 57856 R-BTA-5205861 https://reactome.org/PathwayBrowser/#/R-BTA-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Bos taurus 57856 R-BTA-5205867 https://reactome.org/PathwayBrowser/#/R-BTA-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Bos taurus 57856 R-BTA-5216234 https://reactome.org/PathwayBrowser/#/R-BTA-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Bos taurus 57856 R-BTA-5218952 https://reactome.org/PathwayBrowser/#/R-BTA-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Bos taurus 57856 R-BTA-5229010 https://reactome.org/PathwayBrowser/#/R-BTA-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) IEA Bos taurus 57856 R-BTA-5229203 https://reactome.org/PathwayBrowser/#/R-BTA-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Bos taurus 57856 R-BTA-5244692 https://reactome.org/PathwayBrowser/#/R-BTA-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Bos taurus 57856 R-BTA-5358484 https://reactome.org/PathwayBrowser/#/R-BTA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Bos taurus 57856 R-BTA-5359451 https://reactome.org/PathwayBrowser/#/R-BTA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Bos taurus 57856 R-BTA-5423038 https://reactome.org/PathwayBrowser/#/R-BTA-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Bos taurus 57856 R-BTA-5634729 https://reactome.org/PathwayBrowser/#/R-BTA-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Bos taurus 57856 R-BTA-5634750 https://reactome.org/PathwayBrowser/#/R-BTA-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Bos taurus 57856 R-BTA-5634802 https://reactome.org/PathwayBrowser/#/R-BTA-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Bos taurus 57856 R-BTA-5637686 https://reactome.org/PathwayBrowser/#/R-BTA-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Bos taurus 57856 R-BTA-5638141 https://reactome.org/PathwayBrowser/#/R-BTA-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) IEA Bos taurus 57856 R-BTA-5638157 https://reactome.org/PathwayBrowser/#/R-BTA-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Bos taurus 57856 R-BTA-5638332 https://reactome.org/PathwayBrowser/#/R-BTA-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Bos taurus 57856 R-BTA-5638333 https://reactome.org/PathwayBrowser/#/R-BTA-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Bos taurus 57856 R-BTA-5649764 https://reactome.org/PathwayBrowser/#/R-BTA-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Bos taurus 57856 R-BTA-5649799 https://reactome.org/PathwayBrowser/#/R-BTA-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Bos taurus 57856 R-BTA-5649800 https://reactome.org/PathwayBrowser/#/R-BTA-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Bos taurus 57856 R-BTA-5649801 https://reactome.org/PathwayBrowser/#/R-BTA-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Bos taurus 57856 R-BTA-5649802 https://reactome.org/PathwayBrowser/#/R-BTA-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Bos taurus 57856 R-BTA-5651654 https://reactome.org/PathwayBrowser/#/R-BTA-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Bos taurus 57856 R-BTA-5651657 https://reactome.org/PathwayBrowser/#/R-BTA-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Bos taurus 57856 R-BTA-5661117 https://reactome.org/PathwayBrowser/#/R-BTA-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Bos taurus 57856 R-BTA-5661126 https://reactome.org/PathwayBrowser/#/R-BTA-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Bos taurus 57856 R-BTA-5676966 https://reactome.org/PathwayBrowser/#/R-BTA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Bos taurus 57856 R-BTA-5682965 https://reactome.org/PathwayBrowser/#/R-BTA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Bos taurus 57856 R-BTA-5696213 https://reactome.org/PathwayBrowser/#/R-BTA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Bos taurus 57856 R-BTA-5696220 https://reactome.org/PathwayBrowser/#/R-BTA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Bos taurus 57856 R-BTA-6786205 https://reactome.org/PathwayBrowser/#/R-BTA-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Bos taurus 57856 R-BTA-6788650 https://reactome.org/PathwayBrowser/#/R-BTA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Bos taurus 57856 R-BTA-6798317 https://reactome.org/PathwayBrowser/#/R-BTA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Bos taurus 57856 R-BTA-6800138 https://reactome.org/PathwayBrowser/#/R-BTA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Bos taurus 57856 R-BTA-6800149 https://reactome.org/PathwayBrowser/#/R-BTA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Bos taurus 57856 R-BTA-6804383 https://reactome.org/PathwayBrowser/#/R-BTA-6804383 PRMT5 methylates TP53 IEA Bos taurus 57856 R-BTA-6805730 https://reactome.org/PathwayBrowser/#/R-BTA-6805730 SETD9 methylates TP53 IEA Bos taurus 57856 R-BTA-6805740 https://reactome.org/PathwayBrowser/#/R-BTA-6805740 SETD8 methylates TP53 IEA Bos taurus 57856 R-BTA-6805755 https://reactome.org/PathwayBrowser/#/R-BTA-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Bos taurus 57856 R-BTA-71286 https://reactome.org/PathwayBrowser/#/R-BTA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Bos taurus 57856 R-BTA-77090 https://reactome.org/PathwayBrowser/#/R-BTA-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Bos taurus 57856 R-BTA-8855062 https://reactome.org/PathwayBrowser/#/R-BTA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Bos taurus 57856 R-BTA-8856945 https://reactome.org/PathwayBrowser/#/R-BTA-8856945 PP2A methylation by LCMT1 IEA Bos taurus 57856 R-BTA-8865237 https://reactome.org/PathwayBrowser/#/R-BTA-8865237 SETD6 methylates RELA in the NFkB complex IEA Bos taurus 57856 R-BTA-8876789 https://reactome.org/PathwayBrowser/#/R-BTA-8876789 CARNMT1 methylates CARN to Anserine IEA Bos taurus 57856 R-BTA-8879123 https://reactome.org/PathwayBrowser/#/R-BTA-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Bos taurus 57856 R-BTA-8931974 https://reactome.org/PathwayBrowser/#/R-BTA-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Bos taurus 57856 R-BTA-8932221 https://reactome.org/PathwayBrowser/#/R-BTA-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Bos taurus 57856 R-BTA-8932243 https://reactome.org/PathwayBrowser/#/R-BTA-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Bos taurus 57856 R-BTA-8932275 https://reactome.org/PathwayBrowser/#/R-BTA-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Bos taurus 57856 R-BTA-8932413 https://reactome.org/PathwayBrowser/#/R-BTA-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Bos taurus 57856 R-BTA-8934735 https://reactome.org/PathwayBrowser/#/R-BTA-8934735 PRMT1 arginine-methylates RUNX1 IEA Bos taurus 57856 R-BTA-8936481 https://reactome.org/PathwayBrowser/#/R-BTA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Bos taurus 57856 R-BTA-8936584 https://reactome.org/PathwayBrowser/#/R-BTA-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Bos taurus 57856 R-BTA-8936608 https://reactome.org/PathwayBrowser/#/R-BTA-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Bos taurus 57856 R-BTA-8936621 https://reactome.org/PathwayBrowser/#/R-BTA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Bos taurus 57856 R-BTA-8937016 https://reactome.org/PathwayBrowser/#/R-BTA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Bos taurus 57856 R-BTA-8937022 https://reactome.org/PathwayBrowser/#/R-BTA-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Bos taurus 57856 R-BTA-8937050 https://reactome.org/PathwayBrowser/#/R-BTA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Bos taurus 57856 R-BTA-8937113 https://reactome.org/PathwayBrowser/#/R-BTA-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Bos taurus 57856 R-BTA-8955010 https://reactome.org/PathwayBrowser/#/R-BTA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Bos taurus 57856 R-BTA-9632182 https://reactome.org/PathwayBrowser/#/R-BTA-9632182 PRMT1 methylates ESRs IEA Bos taurus 57856 R-BTA-9647977 https://reactome.org/PathwayBrowser/#/R-BTA-9647977 ICMT methylates S-Farn RAS proteins IEA Bos taurus 57856 R-BTA-9748979 https://reactome.org/PathwayBrowser/#/R-BTA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Bos taurus 57856 R-BTA-9748983 https://reactome.org/PathwayBrowser/#/R-BTA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Bos taurus 57856 R-BTA-9854315 https://reactome.org/PathwayBrowser/#/R-BTA-9854315 CSKMT methylates Citrate Synthase IEA Bos taurus 57856 R-CEL-174401 https://reactome.org/PathwayBrowser/#/R-CEL-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Caenorhabditis elegans 57856 R-CEL-175987 https://reactome.org/PathwayBrowser/#/R-CEL-175987 NNMT transfers CH3 from AdoMet to PY IEA Caenorhabditis elegans 57856 R-CEL-209903 https://reactome.org/PathwayBrowser/#/R-CEL-209903 Noradrenaline is converted to adrenaline IEA Caenorhabditis elegans 57856 R-CEL-2162186 https://reactome.org/PathwayBrowser/#/R-CEL-2162186 COQ3 methylates DeMQ10H2 IEA Caenorhabditis elegans 57856 R-CEL-2162188 https://reactome.org/PathwayBrowser/#/R-CEL-2162188 COQ5 methylates MDMQ10H2 IEA Caenorhabditis elegans 57856 R-CEL-2162193 https://reactome.org/PathwayBrowser/#/R-CEL-2162193 COQ3 methylates DHDB IEA Caenorhabditis elegans 57856 R-CEL-2301205 https://reactome.org/PathwayBrowser/#/R-CEL-2301205 SETD8 monomethylates histone H4 IEA Caenorhabditis elegans 57856 R-CEL-3149518 https://reactome.org/PathwayBrowser/#/R-CEL-3149518 MTRR reduces cob(II)alamin to meCbl IEA Caenorhabditis elegans 57856 R-CEL-3240295 https://reactome.org/PathwayBrowser/#/R-CEL-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Caenorhabditis elegans 57856 R-CEL-4827382 https://reactome.org/PathwayBrowser/#/R-CEL-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Caenorhabditis elegans 57856 R-CEL-4827383 https://reactome.org/PathwayBrowser/#/R-CEL-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Caenorhabditis elegans 57856 R-CEL-5159245 https://reactome.org/PathwayBrowser/#/R-CEL-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Caenorhabditis elegans 57856 R-CEL-5205798 https://reactome.org/PathwayBrowser/#/R-CEL-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Caenorhabditis elegans 57856 R-CEL-5205867 https://reactome.org/PathwayBrowser/#/R-CEL-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Caenorhabditis elegans 57856 R-CEL-5218952 https://reactome.org/PathwayBrowser/#/R-CEL-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Caenorhabditis elegans 57856 R-CEL-5244692 https://reactome.org/PathwayBrowser/#/R-CEL-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Caenorhabditis elegans 57856 R-CEL-5358484 https://reactome.org/PathwayBrowser/#/R-CEL-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Caenorhabditis elegans 57856 R-CEL-5359451 https://reactome.org/PathwayBrowser/#/R-CEL-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Caenorhabditis elegans 57856 R-CEL-5423038 https://reactome.org/PathwayBrowser/#/R-CEL-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Caenorhabditis elegans 57856 R-CEL-5634802 https://reactome.org/PathwayBrowser/#/R-CEL-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Caenorhabditis elegans 57856 R-CEL-5637686 https://reactome.org/PathwayBrowser/#/R-CEL-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Caenorhabditis elegans 57856 R-CEL-5638157 https://reactome.org/PathwayBrowser/#/R-CEL-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Caenorhabditis elegans 57856 R-CEL-5649764 https://reactome.org/PathwayBrowser/#/R-CEL-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Caenorhabditis elegans 57856 R-CEL-5649799 https://reactome.org/PathwayBrowser/#/R-CEL-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Caenorhabditis elegans 57856 R-CEL-5649801 https://reactome.org/PathwayBrowser/#/R-CEL-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Caenorhabditis elegans 57856 R-CEL-5661126 https://reactome.org/PathwayBrowser/#/R-CEL-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Caenorhabditis elegans 57856 R-CEL-5676966 https://reactome.org/PathwayBrowser/#/R-CEL-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Caenorhabditis elegans 57856 R-CEL-6788650 https://reactome.org/PathwayBrowser/#/R-CEL-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Caenorhabditis elegans 57856 R-CEL-6800138 https://reactome.org/PathwayBrowser/#/R-CEL-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Caenorhabditis elegans 57856 R-CEL-6800149 https://reactome.org/PathwayBrowser/#/R-CEL-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Caenorhabditis elegans 57856 R-CEL-77090 https://reactome.org/PathwayBrowser/#/R-CEL-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Caenorhabditis elegans 57856 R-CEL-8855062 https://reactome.org/PathwayBrowser/#/R-CEL-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Caenorhabditis elegans 57856 R-CEL-8856945 https://reactome.org/PathwayBrowser/#/R-CEL-8856945 PP2A methylation by LCMT1 IEA Caenorhabditis elegans 57856 R-CEL-8931858 https://reactome.org/PathwayBrowser/#/R-CEL-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Caenorhabditis elegans 57856 R-CEL-8931974 https://reactome.org/PathwayBrowser/#/R-CEL-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Caenorhabditis elegans 57856 R-CEL-8932276 https://reactome.org/PathwayBrowser/#/R-CEL-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Caenorhabditis elegans 57856 R-CEL-8932413 https://reactome.org/PathwayBrowser/#/R-CEL-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Caenorhabditis elegans 57856 R-CEL-8934735 https://reactome.org/PathwayBrowser/#/R-CEL-8934735 PRMT1 arginine-methylates RUNX1 IEA Caenorhabditis elegans 57856 R-CEL-8936481 https://reactome.org/PathwayBrowser/#/R-CEL-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Caenorhabditis elegans 57856 R-CEL-8936584 https://reactome.org/PathwayBrowser/#/R-CEL-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Caenorhabditis elegans 57856 R-CEL-8936608 https://reactome.org/PathwayBrowser/#/R-CEL-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Caenorhabditis elegans 57856 R-CEL-8936621 https://reactome.org/PathwayBrowser/#/R-CEL-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Caenorhabditis elegans 57856 R-CEL-8937016 https://reactome.org/PathwayBrowser/#/R-CEL-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Caenorhabditis elegans 57856 R-CEL-8937022 https://reactome.org/PathwayBrowser/#/R-CEL-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Caenorhabditis elegans 57856 R-CEL-8937050 https://reactome.org/PathwayBrowser/#/R-CEL-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Caenorhabditis elegans 57856 R-CEL-8937113 https://reactome.org/PathwayBrowser/#/R-CEL-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Caenorhabditis elegans 57856 R-CEL-9647977 https://reactome.org/PathwayBrowser/#/R-CEL-9647977 ICMT methylates S-Farn RAS proteins IEA Caenorhabditis elegans 57856 R-CFA-1483174 https://reactome.org/PathwayBrowser/#/R-CFA-1483174 PE is methylated to PC by PEMT IEA Canis familiaris 57856 R-CFA-158609 https://reactome.org/PathwayBrowser/#/R-CFA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Canis familiaris 57856 R-CFA-174401 https://reactome.org/PathwayBrowser/#/R-CFA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Canis familiaris 57856 R-CFA-175983 https://reactome.org/PathwayBrowser/#/R-CFA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Canis familiaris 57856 R-CFA-175987 https://reactome.org/PathwayBrowser/#/R-CFA-175987 NNMT transfers CH3 from AdoMet to PY IEA Canis familiaris 57856 R-CFA-209821 https://reactome.org/PathwayBrowser/#/R-CFA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Canis familiaris 57856 R-CFA-209903 https://reactome.org/PathwayBrowser/#/R-CFA-209903 Noradrenaline is converted to adrenaline IEA Canis familiaris 57856 R-CFA-212263 https://reactome.org/PathwayBrowser/#/R-CFA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Canis familiaris 57856 R-CFA-212269 https://reactome.org/PathwayBrowser/#/R-CFA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Canis familiaris 57856 R-CFA-2162186 https://reactome.org/PathwayBrowser/#/R-CFA-2162186 COQ3 methylates DeMQ10H2 IEA Canis familiaris 57856 R-CFA-2162188 https://reactome.org/PathwayBrowser/#/R-CFA-2162188 COQ5 methylates MDMQ10H2 IEA Canis familiaris 57856 R-CFA-2162193 https://reactome.org/PathwayBrowser/#/R-CFA-2162193 COQ3 methylates DHDB IEA Canis familiaris 57856 R-CFA-3149518 https://reactome.org/PathwayBrowser/#/R-CFA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Canis familiaris 57856 R-CFA-3222237 https://reactome.org/PathwayBrowser/#/R-CFA-3222237 SMYD2 methylates TP53 IEA Canis familiaris 57856 R-CFA-3240295 https://reactome.org/PathwayBrowser/#/R-CFA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Canis familiaris 57856 R-CFA-3788745 https://reactome.org/PathwayBrowser/#/R-CFA-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Canis familiaris 57856 R-CFA-3788748 https://reactome.org/PathwayBrowser/#/R-CFA-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Canis familiaris 57856 R-CFA-379387 https://reactome.org/PathwayBrowser/#/R-CFA-379387 COMT transfers Met to DA to form 3MT IEA Canis familiaris 57856 R-CFA-427527 https://reactome.org/PathwayBrowser/#/R-CFA-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Canis familiaris 57856 R-CFA-4827382 https://reactome.org/PathwayBrowser/#/R-CFA-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Canis familiaris 57856 R-CFA-4827383 https://reactome.org/PathwayBrowser/#/R-CFA-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Canis familiaris 57856 R-CFA-5159245 https://reactome.org/PathwayBrowser/#/R-CFA-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Canis familiaris 57856 R-CFA-5205798 https://reactome.org/PathwayBrowser/#/R-CFA-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Canis familiaris 57856 R-CFA-5205799 https://reactome.org/PathwayBrowser/#/R-CFA-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Canis familiaris 57856 R-CFA-5205820 https://reactome.org/PathwayBrowser/#/R-CFA-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Canis familiaris 57856 R-CFA-5205822 https://reactome.org/PathwayBrowser/#/R-CFA-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 IEA Canis familiaris 57856 R-CFA-5205824 https://reactome.org/PathwayBrowser/#/R-CFA-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Canis familiaris 57856 R-CFA-5205861 https://reactome.org/PathwayBrowser/#/R-CFA-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Canis familiaris 57856 R-CFA-5205867 https://reactome.org/PathwayBrowser/#/R-CFA-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Canis familiaris 57856 R-CFA-5216234 https://reactome.org/PathwayBrowser/#/R-CFA-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Canis familiaris 57856 R-CFA-5218952 https://reactome.org/PathwayBrowser/#/R-CFA-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Canis familiaris 57856 R-CFA-5229010 https://reactome.org/PathwayBrowser/#/R-CFA-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) IEA Canis familiaris 57856 R-CFA-5229203 https://reactome.org/PathwayBrowser/#/R-CFA-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Canis familiaris 57856 R-CFA-5244692 https://reactome.org/PathwayBrowser/#/R-CFA-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Canis familiaris 57856 R-CFA-5358484 https://reactome.org/PathwayBrowser/#/R-CFA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Canis familiaris 57856 R-CFA-5359451 https://reactome.org/PathwayBrowser/#/R-CFA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Canis familiaris 57856 R-CFA-5634729 https://reactome.org/PathwayBrowser/#/R-CFA-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Canis familiaris 57856 R-CFA-5634750 https://reactome.org/PathwayBrowser/#/R-CFA-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Canis familiaris 57856 R-CFA-5634802 https://reactome.org/PathwayBrowser/#/R-CFA-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Canis familiaris 57856 R-CFA-5637686 https://reactome.org/PathwayBrowser/#/R-CFA-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Canis familiaris 57856 R-CFA-5638141 https://reactome.org/PathwayBrowser/#/R-CFA-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) IEA Canis familiaris 57856 R-CFA-5638157 https://reactome.org/PathwayBrowser/#/R-CFA-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Canis familiaris 57856 R-CFA-5638332 https://reactome.org/PathwayBrowser/#/R-CFA-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Canis familiaris 57856 R-CFA-5638333 https://reactome.org/PathwayBrowser/#/R-CFA-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Canis familiaris 57856 R-CFA-5649764 https://reactome.org/PathwayBrowser/#/R-CFA-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Canis familiaris 57856 R-CFA-5649799 https://reactome.org/PathwayBrowser/#/R-CFA-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Canis familiaris 57856 R-CFA-5649800 https://reactome.org/PathwayBrowser/#/R-CFA-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Canis familiaris 57856 R-CFA-5649801 https://reactome.org/PathwayBrowser/#/R-CFA-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Canis familiaris 57856 R-CFA-5649802 https://reactome.org/PathwayBrowser/#/R-CFA-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Canis familiaris 57856 R-CFA-5651654 https://reactome.org/PathwayBrowser/#/R-CFA-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Canis familiaris 57856 R-CFA-5651657 https://reactome.org/PathwayBrowser/#/R-CFA-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Canis familiaris 57856 R-CFA-5661117 https://reactome.org/PathwayBrowser/#/R-CFA-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Canis familiaris 57856 R-CFA-5661126 https://reactome.org/PathwayBrowser/#/R-CFA-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Canis familiaris 57856 R-CFA-5676966 https://reactome.org/PathwayBrowser/#/R-CFA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Canis familiaris 57856 R-CFA-5682965 https://reactome.org/PathwayBrowser/#/R-CFA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Canis familiaris 57856 R-CFA-6786205 https://reactome.org/PathwayBrowser/#/R-CFA-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Canis familiaris 57856 R-CFA-6798317 https://reactome.org/PathwayBrowser/#/R-CFA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Canis familiaris 57856 R-CFA-6800138 https://reactome.org/PathwayBrowser/#/R-CFA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Canis familiaris 57856 R-CFA-6800149 https://reactome.org/PathwayBrowser/#/R-CFA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Canis familiaris 57856 R-CFA-6804383 https://reactome.org/PathwayBrowser/#/R-CFA-6804383 PRMT5 methylates TP53 IEA Canis familiaris 57856 R-CFA-6805730 https://reactome.org/PathwayBrowser/#/R-CFA-6805730 SETD9 methylates TP53 IEA Canis familiaris 57856 R-CFA-6805755 https://reactome.org/PathwayBrowser/#/R-CFA-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Canis familiaris 57856 R-CFA-71286 https://reactome.org/PathwayBrowser/#/R-CFA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Canis familiaris 57856 R-CFA-77090 https://reactome.org/PathwayBrowser/#/R-CFA-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Canis familiaris 57856 R-CFA-8855062 https://reactome.org/PathwayBrowser/#/R-CFA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Canis familiaris 57856 R-CFA-8856945 https://reactome.org/PathwayBrowser/#/R-CFA-8856945 PP2A methylation by LCMT1 IEA Canis familiaris 57856 R-CFA-8865237 https://reactome.org/PathwayBrowser/#/R-CFA-8865237 SETD6 methylates RELA in the NFkB complex IEA Canis familiaris 57856 R-CFA-8876789 https://reactome.org/PathwayBrowser/#/R-CFA-8876789 CARNMT1 methylates CARN to Anserine IEA Canis familiaris 57856 R-CFA-8879123 https://reactome.org/PathwayBrowser/#/R-CFA-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Canis familiaris 57856 R-CFA-8931858 https://reactome.org/PathwayBrowser/#/R-CFA-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Canis familiaris 57856 R-CFA-8931974 https://reactome.org/PathwayBrowser/#/R-CFA-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Canis familiaris 57856 R-CFA-8932221 https://reactome.org/PathwayBrowser/#/R-CFA-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Canis familiaris 57856 R-CFA-8932243 https://reactome.org/PathwayBrowser/#/R-CFA-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Canis familiaris 57856 R-CFA-8932275 https://reactome.org/PathwayBrowser/#/R-CFA-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Canis familiaris 57856 R-CFA-8932276 https://reactome.org/PathwayBrowser/#/R-CFA-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Canis familiaris 57856 R-CFA-8932413 https://reactome.org/PathwayBrowser/#/R-CFA-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Canis familiaris 57856 R-CFA-8934735 https://reactome.org/PathwayBrowser/#/R-CFA-8934735 PRMT1 arginine-methylates RUNX1 IEA Canis familiaris 57856 R-CFA-8936481 https://reactome.org/PathwayBrowser/#/R-CFA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Canis familiaris 57856 R-CFA-8936584 https://reactome.org/PathwayBrowser/#/R-CFA-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Canis familiaris 57856 R-CFA-8936608 https://reactome.org/PathwayBrowser/#/R-CFA-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Canis familiaris 57856 R-CFA-8936621 https://reactome.org/PathwayBrowser/#/R-CFA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Canis familiaris 57856 R-CFA-8937016 https://reactome.org/PathwayBrowser/#/R-CFA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Canis familiaris 57856 R-CFA-8937022 https://reactome.org/PathwayBrowser/#/R-CFA-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Canis familiaris 57856 R-CFA-8937050 https://reactome.org/PathwayBrowser/#/R-CFA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Canis familiaris 57856 R-CFA-8937113 https://reactome.org/PathwayBrowser/#/R-CFA-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Canis familiaris 57856 R-CFA-8955010 https://reactome.org/PathwayBrowser/#/R-CFA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Canis familiaris 57856 R-CFA-9632182 https://reactome.org/PathwayBrowser/#/R-CFA-9632182 PRMT1 methylates ESRs IEA Canis familiaris 57856 R-CFA-9748979 https://reactome.org/PathwayBrowser/#/R-CFA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Canis familiaris 57856 R-CFA-9748983 https://reactome.org/PathwayBrowser/#/R-CFA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Canis familiaris 57856 R-CFA-9854315 https://reactome.org/PathwayBrowser/#/R-CFA-9854315 CSKMT methylates Citrate Synthase IEA Canis familiaris 57856 R-DDI-1483174 https://reactome.org/PathwayBrowser/#/R-DDI-1483174 PE is methylated to PC by PEMT IEA Dictyostelium discoideum 57856 R-DDI-174401 https://reactome.org/PathwayBrowser/#/R-DDI-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Dictyostelium discoideum 57856 R-DDI-209821 https://reactome.org/PathwayBrowser/#/R-DDI-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Dictyostelium discoideum 57856 R-DDI-2162186 https://reactome.org/PathwayBrowser/#/R-DDI-2162186 COQ3 methylates DeMQ10H2 IEA Dictyostelium discoideum 57856 R-DDI-2162188 https://reactome.org/PathwayBrowser/#/R-DDI-2162188 COQ5 methylates MDMQ10H2 IEA Dictyostelium discoideum 57856 R-DDI-2162193 https://reactome.org/PathwayBrowser/#/R-DDI-2162193 COQ3 methylates DHDB IEA Dictyostelium discoideum 57856 R-DDI-3149518 https://reactome.org/PathwayBrowser/#/R-DDI-3149518 MTRR reduces cob(II)alamin to meCbl IEA Dictyostelium discoideum 57856 R-DDI-427527 https://reactome.org/PathwayBrowser/#/R-DDI-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Dictyostelium discoideum 57856 R-DDI-4827382 https://reactome.org/PathwayBrowser/#/R-DDI-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Dictyostelium discoideum 57856 R-DDI-4827383 https://reactome.org/PathwayBrowser/#/R-DDI-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Dictyostelium discoideum 57856 R-DDI-5159245 https://reactome.org/PathwayBrowser/#/R-DDI-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Dictyostelium discoideum 57856 R-DDI-5205798 https://reactome.org/PathwayBrowser/#/R-DDI-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Dictyostelium discoideum 57856 R-DDI-5205799 https://reactome.org/PathwayBrowser/#/R-DDI-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Dictyostelium discoideum 57856 R-DDI-5205867 https://reactome.org/PathwayBrowser/#/R-DDI-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Dictyostelium discoideum 57856 R-DDI-5218952 https://reactome.org/PathwayBrowser/#/R-DDI-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Dictyostelium discoideum 57856 R-DDI-5244692 https://reactome.org/PathwayBrowser/#/R-DDI-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Dictyostelium discoideum 57856 R-DDI-5358484 https://reactome.org/PathwayBrowser/#/R-DDI-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Dictyostelium discoideum 57856 R-DDI-5637686 https://reactome.org/PathwayBrowser/#/R-DDI-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Dictyostelium discoideum 57856 R-DDI-5638157 https://reactome.org/PathwayBrowser/#/R-DDI-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Dictyostelium discoideum 57856 R-DDI-5638333 https://reactome.org/PathwayBrowser/#/R-DDI-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Dictyostelium discoideum 57856 R-DDI-5649764 https://reactome.org/PathwayBrowser/#/R-DDI-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Dictyostelium discoideum 57856 R-DDI-5649799 https://reactome.org/PathwayBrowser/#/R-DDI-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Dictyostelium discoideum 57856 R-DDI-5649800 https://reactome.org/PathwayBrowser/#/R-DDI-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Dictyostelium discoideum 57856 R-DDI-5649801 https://reactome.org/PathwayBrowser/#/R-DDI-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Dictyostelium discoideum 57856 R-DDI-5649802 https://reactome.org/PathwayBrowser/#/R-DDI-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Dictyostelium discoideum 57856 R-DDI-5661117 https://reactome.org/PathwayBrowser/#/R-DDI-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Dictyostelium discoideum 57856 R-DDI-5661126 https://reactome.org/PathwayBrowser/#/R-DDI-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Dictyostelium discoideum 57856 R-DDI-5676966 https://reactome.org/PathwayBrowser/#/R-DDI-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Dictyostelium discoideum 57856 R-DDI-5682965 https://reactome.org/PathwayBrowser/#/R-DDI-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Dictyostelium discoideum 57856 R-DDI-6788650 https://reactome.org/PathwayBrowser/#/R-DDI-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Dictyostelium discoideum 57856 R-DDI-6800138 https://reactome.org/PathwayBrowser/#/R-DDI-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Dictyostelium discoideum 57856 R-DDI-6800149 https://reactome.org/PathwayBrowser/#/R-DDI-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Dictyostelium discoideum 57856 R-DDI-77090 https://reactome.org/PathwayBrowser/#/R-DDI-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Dictyostelium discoideum 57856 R-DDI-8856945 https://reactome.org/PathwayBrowser/#/R-DDI-8856945 PP2A methylation by LCMT1 IEA Dictyostelium discoideum 57856 R-DDI-8876789 https://reactome.org/PathwayBrowser/#/R-DDI-8876789 CARNMT1 methylates CARN to Anserine IEA Dictyostelium discoideum 57856 R-DDI-8879123 https://reactome.org/PathwayBrowser/#/R-DDI-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Dictyostelium discoideum 57856 R-DDI-8931974 https://reactome.org/PathwayBrowser/#/R-DDI-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Dictyostelium discoideum 57856 R-DDI-8932221 https://reactome.org/PathwayBrowser/#/R-DDI-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Dictyostelium discoideum 57856 R-DDI-8932276 https://reactome.org/PathwayBrowser/#/R-DDI-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Dictyostelium discoideum 57856 R-DDI-8932413 https://reactome.org/PathwayBrowser/#/R-DDI-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Dictyostelium discoideum 57856 R-DME-174401 https://reactome.org/PathwayBrowser/#/R-DME-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Drosophila melanogaster 57856 R-DME-212263 https://reactome.org/PathwayBrowser/#/R-DME-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Drosophila melanogaster 57856 R-DME-212269 https://reactome.org/PathwayBrowser/#/R-DME-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Drosophila melanogaster 57856 R-DME-2162186 https://reactome.org/PathwayBrowser/#/R-DME-2162186 COQ3 methylates DeMQ10H2 IEA Drosophila melanogaster 57856 R-DME-2162188 https://reactome.org/PathwayBrowser/#/R-DME-2162188 COQ5 methylates MDMQ10H2 IEA Drosophila melanogaster 57856 R-DME-2162193 https://reactome.org/PathwayBrowser/#/R-DME-2162193 COQ3 methylates DHDB IEA Drosophila melanogaster 57856 R-DME-2301205 https://reactome.org/PathwayBrowser/#/R-DME-2301205 SETD8 monomethylates histone H4 IEA Drosophila melanogaster 57856 R-DME-3222237 https://reactome.org/PathwayBrowser/#/R-DME-3222237 SMYD2 methylates TP53 IEA Drosophila melanogaster 57856 R-DME-3240295 https://reactome.org/PathwayBrowser/#/R-DME-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Drosophila melanogaster 57856 R-DME-3364026 https://reactome.org/PathwayBrowser/#/R-DME-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Drosophila melanogaster 57856 R-DME-3788745 https://reactome.org/PathwayBrowser/#/R-DME-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Drosophila melanogaster 57856 R-DME-3788748 https://reactome.org/PathwayBrowser/#/R-DME-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Drosophila melanogaster 57856 R-DME-427527 https://reactome.org/PathwayBrowser/#/R-DME-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Drosophila melanogaster 57856 R-DME-5205798 https://reactome.org/PathwayBrowser/#/R-DME-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Drosophila melanogaster 57856 R-DME-5205861 https://reactome.org/PathwayBrowser/#/R-DME-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Drosophila melanogaster 57856 R-DME-5205867 https://reactome.org/PathwayBrowser/#/R-DME-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Drosophila melanogaster 57856 R-DME-5216234 https://reactome.org/PathwayBrowser/#/R-DME-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Drosophila melanogaster 57856 R-DME-5358484 https://reactome.org/PathwayBrowser/#/R-DME-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Drosophila melanogaster 57856 R-DME-5423038 https://reactome.org/PathwayBrowser/#/R-DME-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Drosophila melanogaster 57856 R-DME-5651654 https://reactome.org/PathwayBrowser/#/R-DME-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Drosophila melanogaster 57856 R-DME-5651657 https://reactome.org/PathwayBrowser/#/R-DME-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Drosophila melanogaster 57856 R-DME-5661126 https://reactome.org/PathwayBrowser/#/R-DME-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Drosophila melanogaster 57856 R-DME-5676966 https://reactome.org/PathwayBrowser/#/R-DME-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Drosophila melanogaster 57856 R-DME-5682965 https://reactome.org/PathwayBrowser/#/R-DME-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Drosophila melanogaster 57856 R-DME-6786205 https://reactome.org/PathwayBrowser/#/R-DME-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Drosophila melanogaster 57856 R-DME-6788650 https://reactome.org/PathwayBrowser/#/R-DME-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Drosophila melanogaster 57856 R-DME-6798317 https://reactome.org/PathwayBrowser/#/R-DME-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Drosophila melanogaster 57856 R-DME-6800138 https://reactome.org/PathwayBrowser/#/R-DME-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Drosophila melanogaster 57856 R-DME-6800149 https://reactome.org/PathwayBrowser/#/R-DME-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Drosophila melanogaster 57856 R-DME-6805740 https://reactome.org/PathwayBrowser/#/R-DME-6805740 SETD8 methylates TP53 IEA Drosophila melanogaster 57856 R-DME-6805755 https://reactome.org/PathwayBrowser/#/R-DME-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Drosophila melanogaster 57856 R-DME-77090 https://reactome.org/PathwayBrowser/#/R-DME-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Drosophila melanogaster 57856 R-DME-8855062 https://reactome.org/PathwayBrowser/#/R-DME-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Drosophila melanogaster 57856 R-DME-8856945 https://reactome.org/PathwayBrowser/#/R-DME-8856945 PP2A methylation by LCMT1 IEA Drosophila melanogaster 57856 R-DME-8876789 https://reactome.org/PathwayBrowser/#/R-DME-8876789 CARNMT1 methylates CARN to Anserine IEA Drosophila melanogaster 57856 R-DME-8879123 https://reactome.org/PathwayBrowser/#/R-DME-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Drosophila melanogaster 57856 R-DME-8931974 https://reactome.org/PathwayBrowser/#/R-DME-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Drosophila melanogaster 57856 R-DME-8932243 https://reactome.org/PathwayBrowser/#/R-DME-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Drosophila melanogaster 57856 R-DME-8932275 https://reactome.org/PathwayBrowser/#/R-DME-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Drosophila melanogaster 57856 R-DME-8932413 https://reactome.org/PathwayBrowser/#/R-DME-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Drosophila melanogaster 57856 R-DME-8934735 https://reactome.org/PathwayBrowser/#/R-DME-8934735 PRMT1 arginine-methylates RUNX1 IEA Drosophila melanogaster 57856 R-DME-8936481 https://reactome.org/PathwayBrowser/#/R-DME-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Drosophila melanogaster 57856 R-DME-8936584 https://reactome.org/PathwayBrowser/#/R-DME-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Drosophila melanogaster 57856 R-DME-8936608 https://reactome.org/PathwayBrowser/#/R-DME-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Drosophila melanogaster 57856 R-DME-8936621 https://reactome.org/PathwayBrowser/#/R-DME-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Drosophila melanogaster 57856 R-DME-8937016 https://reactome.org/PathwayBrowser/#/R-DME-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Drosophila melanogaster 57856 R-DME-8937022 https://reactome.org/PathwayBrowser/#/R-DME-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Drosophila melanogaster 57856 R-DME-8937050 https://reactome.org/PathwayBrowser/#/R-DME-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Drosophila melanogaster 57856 R-DME-8937113 https://reactome.org/PathwayBrowser/#/R-DME-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Drosophila melanogaster 57856 R-DME-9632182 https://reactome.org/PathwayBrowser/#/R-DME-9632182 PRMT1 methylates ESRs IEA Drosophila melanogaster 57856 R-DME-9647977 https://reactome.org/PathwayBrowser/#/R-DME-9647977 ICMT methylates S-Farn RAS proteins IEA Drosophila melanogaster 57856 R-DRE-1483174 https://reactome.org/PathwayBrowser/#/R-DRE-1483174 PE is methylated to PC by PEMT IEA Danio rerio 57856 R-DRE-158609 https://reactome.org/PathwayBrowser/#/R-DRE-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Danio rerio 57856 R-DRE-174401 https://reactome.org/PathwayBrowser/#/R-DRE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Danio rerio 57856 R-DRE-175983 https://reactome.org/PathwayBrowser/#/R-DRE-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Danio rerio 57856 R-DRE-175987 https://reactome.org/PathwayBrowser/#/R-DRE-175987 NNMT transfers CH3 from AdoMet to PY IEA Danio rerio 57856 R-DRE-209821 https://reactome.org/PathwayBrowser/#/R-DRE-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Danio rerio 57856 R-DRE-212263 https://reactome.org/PathwayBrowser/#/R-DRE-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Danio rerio 57856 R-DRE-212269 https://reactome.org/PathwayBrowser/#/R-DRE-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Danio rerio 57856 R-DRE-2162186 https://reactome.org/PathwayBrowser/#/R-DRE-2162186 COQ3 methylates DeMQ10H2 IEA Danio rerio 57856 R-DRE-2162188 https://reactome.org/PathwayBrowser/#/R-DRE-2162188 COQ5 methylates MDMQ10H2 IEA Danio rerio 57856 R-DRE-2162193 https://reactome.org/PathwayBrowser/#/R-DRE-2162193 COQ3 methylates DHDB IEA Danio rerio 57856 R-DRE-2301205 https://reactome.org/PathwayBrowser/#/R-DRE-2301205 SETD8 monomethylates histone H4 IEA Danio rerio 57856 R-DRE-3222237 https://reactome.org/PathwayBrowser/#/R-DRE-3222237 SMYD2 methylates TP53 IEA Danio rerio 57856 R-DRE-3240295 https://reactome.org/PathwayBrowser/#/R-DRE-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Danio rerio 57856 R-DRE-379387 https://reactome.org/PathwayBrowser/#/R-DRE-379387 COMT transfers Met to DA to form 3MT IEA Danio rerio 57856 R-DRE-5205798 https://reactome.org/PathwayBrowser/#/R-DRE-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Danio rerio 57856 R-DRE-5205820 https://reactome.org/PathwayBrowser/#/R-DRE-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Danio rerio 57856 R-DRE-5205861 https://reactome.org/PathwayBrowser/#/R-DRE-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Danio rerio 57856 R-DRE-5216234 https://reactome.org/PathwayBrowser/#/R-DRE-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Danio rerio 57856 R-DRE-5229203 https://reactome.org/PathwayBrowser/#/R-DRE-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Danio rerio 57856 R-DRE-5359451 https://reactome.org/PathwayBrowser/#/R-DRE-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Danio rerio 57856 R-DRE-5423038 https://reactome.org/PathwayBrowser/#/R-DRE-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Danio rerio 57856 R-DRE-5651654 https://reactome.org/PathwayBrowser/#/R-DRE-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Danio rerio 57856 R-DRE-5651657 https://reactome.org/PathwayBrowser/#/R-DRE-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Danio rerio 57856 R-DRE-5661126 https://reactome.org/PathwayBrowser/#/R-DRE-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Danio rerio 57856 R-DRE-5676966 https://reactome.org/PathwayBrowser/#/R-DRE-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Danio rerio 57856 R-DRE-5696213 https://reactome.org/PathwayBrowser/#/R-DRE-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Danio rerio 57856 R-DRE-5696220 https://reactome.org/PathwayBrowser/#/R-DRE-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Danio rerio 57856 R-DRE-6788650 https://reactome.org/PathwayBrowser/#/R-DRE-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Danio rerio 57856 R-DRE-6798317 https://reactome.org/PathwayBrowser/#/R-DRE-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Danio rerio 57856 R-DRE-6800138 https://reactome.org/PathwayBrowser/#/R-DRE-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Danio rerio 57856 R-DRE-6800149 https://reactome.org/PathwayBrowser/#/R-DRE-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Danio rerio 57856 R-DRE-6804383 https://reactome.org/PathwayBrowser/#/R-DRE-6804383 PRMT5 methylates TP53 IEA Danio rerio 57856 R-DRE-6805740 https://reactome.org/PathwayBrowser/#/R-DRE-6805740 SETD8 methylates TP53 IEA Danio rerio 57856 R-DRE-71286 https://reactome.org/PathwayBrowser/#/R-DRE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Danio rerio 57856 R-DRE-8855062 https://reactome.org/PathwayBrowser/#/R-DRE-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Danio rerio 57856 R-DRE-8856945 https://reactome.org/PathwayBrowser/#/R-DRE-8856945 PP2A methylation by LCMT1 IEA Danio rerio 57856 R-DRE-8865237 https://reactome.org/PathwayBrowser/#/R-DRE-8865237 SETD6 methylates RELA in the NFkB complex IEA Danio rerio 57856 R-DRE-8879123 https://reactome.org/PathwayBrowser/#/R-DRE-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Danio rerio 57856 R-DRE-8931858 https://reactome.org/PathwayBrowser/#/R-DRE-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Danio rerio 57856 R-DRE-8931974 https://reactome.org/PathwayBrowser/#/R-DRE-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Danio rerio 57856 R-DRE-8932221 https://reactome.org/PathwayBrowser/#/R-DRE-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Danio rerio 57856 R-DRE-8932243 https://reactome.org/PathwayBrowser/#/R-DRE-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Danio rerio 57856 R-DRE-8932275 https://reactome.org/PathwayBrowser/#/R-DRE-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Danio rerio 57856 R-DRE-8932413 https://reactome.org/PathwayBrowser/#/R-DRE-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Danio rerio 57856 R-DRE-8936584 https://reactome.org/PathwayBrowser/#/R-DRE-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Danio rerio 57856 R-DRE-8936608 https://reactome.org/PathwayBrowser/#/R-DRE-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Danio rerio 57856 R-DRE-8937022 https://reactome.org/PathwayBrowser/#/R-DRE-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Danio rerio 57856 R-DRE-8937113 https://reactome.org/PathwayBrowser/#/R-DRE-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Danio rerio 57856 R-DRE-8955010 https://reactome.org/PathwayBrowser/#/R-DRE-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Danio rerio 57856 R-DRE-9647977 https://reactome.org/PathwayBrowser/#/R-DRE-9647977 ICMT methylates S-Farn RAS proteins IEA Danio rerio 57856 R-DRE-9748979 https://reactome.org/PathwayBrowser/#/R-DRE-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Danio rerio 57856 R-DRE-9748983 https://reactome.org/PathwayBrowser/#/R-DRE-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Danio rerio 57856 R-DRE-9854315 https://reactome.org/PathwayBrowser/#/R-DRE-9854315 CSKMT methylates Citrate Synthase IEA Danio rerio 57856 R-GGA-1483174 https://reactome.org/PathwayBrowser/#/R-GGA-1483174 PE is methylated to PC by PEMT IEA Gallus gallus 57856 R-GGA-158609 https://reactome.org/PathwayBrowser/#/R-GGA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Gallus gallus 57856 R-GGA-174401 https://reactome.org/PathwayBrowser/#/R-GGA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Gallus gallus 57856 R-GGA-175983 https://reactome.org/PathwayBrowser/#/R-GGA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Gallus gallus 57856 R-GGA-209821 https://reactome.org/PathwayBrowser/#/R-GGA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Gallus gallus 57856 R-GGA-209903 https://reactome.org/PathwayBrowser/#/R-GGA-209903 Noradrenaline is converted to adrenaline IEA Gallus gallus 57856 R-GGA-212263 https://reactome.org/PathwayBrowser/#/R-GGA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Gallus gallus 57856 R-GGA-212269 https://reactome.org/PathwayBrowser/#/R-GGA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Gallus gallus 57856 R-GGA-2162186 https://reactome.org/PathwayBrowser/#/R-GGA-2162186 COQ3 methylates DeMQ10H2 IEA Gallus gallus 57856 R-GGA-2162188 https://reactome.org/PathwayBrowser/#/R-GGA-2162188 COQ5 methylates MDMQ10H2 IEA Gallus gallus 57856 R-GGA-2162193 https://reactome.org/PathwayBrowser/#/R-GGA-2162193 COQ3 methylates DHDB IEA Gallus gallus 57856 R-GGA-2301205 https://reactome.org/PathwayBrowser/#/R-GGA-2301205 SETD8 monomethylates histone H4 IEA Gallus gallus 57856 R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus 57856 R-GGA-3240295 https://reactome.org/PathwayBrowser/#/R-GGA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Gallus gallus 57856 R-GGA-3364026 https://reactome.org/PathwayBrowser/#/R-GGA-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Gallus gallus 57856 R-GGA-379387 https://reactome.org/PathwayBrowser/#/R-GGA-379387 COMT transfers Met to DA to form 3MT IEA Gallus gallus 57856 R-GGA-5358484 https://reactome.org/PathwayBrowser/#/R-GGA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Gallus gallus 57856 R-GGA-5423038 https://reactome.org/PathwayBrowser/#/R-GGA-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Gallus gallus 57856 R-GGA-5651654 https://reactome.org/PathwayBrowser/#/R-GGA-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Gallus gallus 57856 R-GGA-5651657 https://reactome.org/PathwayBrowser/#/R-GGA-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Gallus gallus 57856 R-GGA-5676966 https://reactome.org/PathwayBrowser/#/R-GGA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Gallus gallus 57856 R-GGA-5682965 https://reactome.org/PathwayBrowser/#/R-GGA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Gallus gallus 57856 R-GGA-5696213 https://reactome.org/PathwayBrowser/#/R-GGA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Gallus gallus 57856 R-GGA-5696220 https://reactome.org/PathwayBrowser/#/R-GGA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Gallus gallus 57856 R-GGA-6786205 https://reactome.org/PathwayBrowser/#/R-GGA-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Gallus gallus 57856 R-GGA-6788650 https://reactome.org/PathwayBrowser/#/R-GGA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Gallus gallus 57856 R-GGA-71286 https://reactome.org/PathwayBrowser/#/R-GGA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Gallus gallus 57856 R-GGA-8855062 https://reactome.org/PathwayBrowser/#/R-GGA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Gallus gallus 57856 R-GGA-8865237 https://reactome.org/PathwayBrowser/#/R-GGA-8865237 SETD6 methylates RELA in the NFkB complex IEA Gallus gallus 57856 R-GGA-8876789 https://reactome.org/PathwayBrowser/#/R-GGA-8876789 CARNMT1 methylates CARN to Anserine IEA Gallus gallus 57856 R-GGA-8879123 https://reactome.org/PathwayBrowser/#/R-GGA-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Gallus gallus 57856 R-GGA-8931974 https://reactome.org/PathwayBrowser/#/R-GGA-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Gallus gallus 57856 R-GGA-8932221 https://reactome.org/PathwayBrowser/#/R-GGA-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Gallus gallus 57856 R-GGA-8932243 https://reactome.org/PathwayBrowser/#/R-GGA-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Gallus gallus 57856 R-GGA-8932275 https://reactome.org/PathwayBrowser/#/R-GGA-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Gallus gallus 57856 R-GGA-8932413 https://reactome.org/PathwayBrowser/#/R-GGA-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Gallus gallus 57856 R-GGA-8936481 https://reactome.org/PathwayBrowser/#/R-GGA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Gallus gallus 57856 R-GGA-8936584 https://reactome.org/PathwayBrowser/#/R-GGA-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Gallus gallus 57856 R-GGA-8936608 https://reactome.org/PathwayBrowser/#/R-GGA-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Gallus gallus 57856 R-GGA-8936621 https://reactome.org/PathwayBrowser/#/R-GGA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Gallus gallus 57856 R-GGA-8937016 https://reactome.org/PathwayBrowser/#/R-GGA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Gallus gallus 57856 R-GGA-8937022 https://reactome.org/PathwayBrowser/#/R-GGA-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Gallus gallus 57856 R-GGA-8937050 https://reactome.org/PathwayBrowser/#/R-GGA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Gallus gallus 57856 R-GGA-8937113 https://reactome.org/PathwayBrowser/#/R-GGA-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Gallus gallus 57856 R-GGA-8955010 https://reactome.org/PathwayBrowser/#/R-GGA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Gallus gallus 57856 R-GGA-9647977 https://reactome.org/PathwayBrowser/#/R-GGA-9647977 ICMT methylates S-Farn RAS proteins IEA Gallus gallus 57856 R-GGA-9748979 https://reactome.org/PathwayBrowser/#/R-GGA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Gallus gallus 57856 R-GGA-9748983 https://reactome.org/PathwayBrowser/#/R-GGA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Gallus gallus 57856 R-HSA-1214188 https://reactome.org/PathwayBrowser/#/R-HSA-1214188 PRDM9 trimethylates histone H3 IEA Homo sapiens 57856 R-HSA-1483174 https://reactome.org/PathwayBrowser/#/R-HSA-1483174 PE is methylated to PC by PEMT TAS Homo sapiens 57856 R-HSA-158609 https://reactome.org/PathwayBrowser/#/R-HSA-158609 TPMT transfers CH3 from AdoMet to 6MP TAS Homo sapiens 57856 R-HSA-174401 https://reactome.org/PathwayBrowser/#/R-HSA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy TAS Homo sapiens 57856 R-HSA-175976 https://reactome.org/PathwayBrowser/#/R-HSA-175976 TMT transfers CH3 from AdoMet to BME TAS Homo sapiens 57856 R-HSA-175983 https://reactome.org/PathwayBrowser/#/R-HSA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ TAS Homo sapiens 57856 R-HSA-175987 https://reactome.org/PathwayBrowser/#/R-HSA-175987 NNMT transfers CH3 from AdoMet to PY TAS Homo sapiens 57856 R-HSA-175993 https://reactome.org/PathwayBrowser/#/R-HSA-175993 HNMT transfers CH3 group from AdoMet to Hist TAS Homo sapiens 57856 R-HSA-209821 https://reactome.org/PathwayBrowser/#/R-HSA-209821 Methylation of N-acetyl-5-HT to form melatonin TAS Homo sapiens 57856 R-HSA-209903 https://reactome.org/PathwayBrowser/#/R-HSA-209903 Noradrenaline is converted to adrenaline TAS Homo sapiens 57856 R-HSA-212263 https://reactome.org/PathwayBrowser/#/R-HSA-212263 PRC2 trimethylates histone H3 at lysine-27 TAS Homo sapiens 57856 R-HSA-212269 https://reactome.org/PathwayBrowser/#/R-HSA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 TAS Homo sapiens 57856 R-HSA-2162186 https://reactome.org/PathwayBrowser/#/R-HSA-2162186 COQ3 methylates DeMQ10H2 TAS Homo sapiens 57856 R-HSA-2162188 https://reactome.org/PathwayBrowser/#/R-HSA-2162188 COQ5 methylates MDMQ10H2 TAS Homo sapiens 57856 R-HSA-2162193 https://reactome.org/PathwayBrowser/#/R-HSA-2162193 COQ3 methylates DHDB TAS Homo sapiens 57856 R-HSA-2301205 https://reactome.org/PathwayBrowser/#/R-HSA-2301205 SETD8 monomethylates histone H4 TAS Homo sapiens 57856 R-HSA-2408536 https://reactome.org/PathwayBrowser/#/R-HSA-2408536 H2Se is methylated to MeSeH by H2Se methyltransferase IEA Homo sapiens 57856 R-HSA-2408541 https://reactome.org/PathwayBrowser/#/R-HSA-2408541 MeSeH is methylated to Me2Se by MeSeH methyltransferase IEA Homo sapiens 57856 R-HSA-2408554 https://reactome.org/PathwayBrowser/#/R-HSA-2408554 Me2Se is methylated to Me3Se+ by INMT IEA Homo sapiens 57856 R-HSA-3149518 https://reactome.org/PathwayBrowser/#/R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl TAS Homo sapiens 57856 R-HSA-3222237 https://reactome.org/PathwayBrowser/#/R-HSA-3222237 SMYD2 methylates TP53 TAS Homo sapiens 57856 R-HSA-3240295 https://reactome.org/PathwayBrowser/#/R-HSA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter TAS Homo sapiens 57856 R-HSA-3364026 https://reactome.org/PathwayBrowser/#/R-HSA-3364026 SET1 complex trimethylates H3K4 at the MYC gene TAS Homo sapiens 57856 R-HSA-3788745 https://reactome.org/PathwayBrowser/#/R-HSA-3788745 EHMT1:EHMT2 methylates IL8 promoter TAS Homo sapiens 57856 R-HSA-3788748 https://reactome.org/PathwayBrowser/#/R-HSA-3788748 EHMT1:EHMT2 methylates IL6 promoter TAS Homo sapiens 57856 R-HSA-379387 https://reactome.org/PathwayBrowser/#/R-HSA-379387 COMT transfers Met to DA to form 3MT TAS Homo sapiens 57856 R-HSA-427336 https://reactome.org/PathwayBrowser/#/R-HSA-427336 TTF1:rRNA promoter:ERCC6:EHMT2 complex dimethylates histone H3 at lysine-9. IEA Homo sapiens 57856 R-HSA-427527 https://reactome.org/PathwayBrowser/#/R-HSA-427527 eNoSC dimethylates histone H3 at lysine-9 TAS Homo sapiens 57856 R-HSA-433672 https://reactome.org/PathwayBrowser/#/R-HSA-433672 NoRC:HDAC:DNMT deacetylates histone H4 and methylates histone H3 IEA Homo sapiens 57856 R-HSA-4827382 https://reactome.org/PathwayBrowser/#/R-HSA-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) TAS Homo sapiens 57856 R-HSA-4827383 https://reactome.org/PathwayBrowser/#/R-HSA-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) TAS Homo sapiens 57856 R-HSA-5159245 https://reactome.org/PathwayBrowser/#/R-HSA-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) TAS Homo sapiens 57856 R-HSA-5205798 https://reactome.org/PathwayBrowser/#/R-HSA-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 TAS Homo sapiens 57856 R-HSA-5205799 https://reactome.org/PathwayBrowser/#/R-HSA-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) TAS Homo sapiens 57856 R-HSA-5205820 https://reactome.org/PathwayBrowser/#/R-HSA-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) TAS Homo sapiens 57856 R-HSA-5205822 https://reactome.org/PathwayBrowser/#/R-HSA-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 TAS Homo sapiens 57856 R-HSA-5205824 https://reactome.org/PathwayBrowser/#/R-HSA-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) TAS Homo sapiens 57856 R-HSA-5205861 https://reactome.org/PathwayBrowser/#/R-HSA-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) TAS Homo sapiens 57856 R-HSA-5205867 https://reactome.org/PathwayBrowser/#/R-HSA-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) TAS Homo sapiens 57856 R-HSA-5216234 https://reactome.org/PathwayBrowser/#/R-HSA-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) TAS Homo sapiens 57856 R-HSA-5218952 https://reactome.org/PathwayBrowser/#/R-HSA-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) TAS Homo sapiens 57856 R-HSA-5227490 https://reactome.org/PathwayBrowser/#/R-HSA-5227490 NoRC:HDAC:DNMT methylates cytosine of the rRNA genes IEA Homo sapiens 57856 R-HSA-5229010 https://reactome.org/PathwayBrowser/#/R-HSA-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) TAS Homo sapiens 57856 R-HSA-5229203 https://reactome.org/PathwayBrowser/#/R-HSA-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) TAS Homo sapiens 57856 R-HSA-5244692 https://reactome.org/PathwayBrowser/#/R-HSA-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) TAS Homo sapiens 57856 R-HSA-5333608 https://reactome.org/PathwayBrowser/#/R-HSA-5333608 GSSebGalNac is reduced and methylated to MeSebGalNac IEA Homo sapiens 57856 R-HSA-5334097 https://reactome.org/PathwayBrowser/#/R-HSA-5334097 DNMT3B:DNMT3L methylates cytosine in DNA IEA Homo sapiens 57856 R-HSA-5334151 https://reactome.org/PathwayBrowser/#/R-HSA-5334151 DNMT1 methylates cytosine in hemimethylated DNA IEA Homo sapiens 57856 R-HSA-5334152 https://reactome.org/PathwayBrowser/#/R-HSA-5334152 DNMT3A:DNMT3L methylates cytosine in DNA IEA Homo sapiens 57856 R-HSA-5358484 https://reactome.org/PathwayBrowser/#/R-HSA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 TAS Homo sapiens 57856 R-HSA-5359451 https://reactome.org/PathwayBrowser/#/R-HSA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA TAS Homo sapiens 57856 R-HSA-5423038 https://reactome.org/PathwayBrowser/#/R-HSA-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) TAS Homo sapiens 57856 R-HSA-5578717 https://reactome.org/PathwayBrowser/#/R-HSA-5578717 BCDIN3D dimethylates 5' phosphate of pre-miR-145 TAS Homo sapiens 57856 R-HSA-5579084 https://reactome.org/PathwayBrowser/#/R-HSA-5579084 Defective AHCY does not hydrolyse AdoHcy TAS Homo sapiens 57856 R-HSA-5629203 https://reactome.org/PathwayBrowser/#/R-HSA-5629203 HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-PIWIL1:piRNA:TDRD6:TDRKH IEA Homo sapiens 57856 R-HSA-5629218 https://reactome.org/PathwayBrowser/#/R-HSA-5629218 HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1 IEA Homo sapiens 57856 R-HSA-5629237 https://reactome.org/PathwayBrowser/#/R-HSA-5629237 HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH IEA Homo sapiens 57856 R-HSA-5634729 https://reactome.org/PathwayBrowser/#/R-HSA-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) TAS Homo sapiens 57856 R-HSA-5634750 https://reactome.org/PathwayBrowser/#/R-HSA-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) TAS Homo sapiens 57856 R-HSA-5634802 https://reactome.org/PathwayBrowser/#/R-HSA-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) TAS Homo sapiens 57856 R-HSA-5637686 https://reactome.org/PathwayBrowser/#/R-HSA-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) TAS Homo sapiens 57856 R-HSA-5638141 https://reactome.org/PathwayBrowser/#/R-HSA-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) TAS Homo sapiens 57856 R-HSA-5638157 https://reactome.org/PathwayBrowser/#/R-HSA-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) TAS Homo sapiens 57856 R-HSA-5638332 https://reactome.org/PathwayBrowser/#/R-HSA-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) TAS Homo sapiens 57856 R-HSA-5638333 https://reactome.org/PathwayBrowser/#/R-HSA-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) TAS Homo sapiens 57856 R-HSA-5649764 https://reactome.org/PathwayBrowser/#/R-HSA-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) TAS Homo sapiens 57856 R-HSA-5649799 https://reactome.org/PathwayBrowser/#/R-HSA-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) TAS Homo sapiens 57856 R-HSA-5649800 https://reactome.org/PathwayBrowser/#/R-HSA-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) TAS Homo sapiens 57856 R-HSA-5649801 https://reactome.org/PathwayBrowser/#/R-HSA-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) TAS Homo sapiens 57856 R-HSA-5649802 https://reactome.org/PathwayBrowser/#/R-HSA-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) TAS Homo sapiens 57856 R-HSA-5651654 https://reactome.org/PathwayBrowser/#/R-HSA-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) TAS Homo sapiens 57856 R-HSA-5651657 https://reactome.org/PathwayBrowser/#/R-HSA-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) TAS Homo sapiens 57856 R-HSA-5661117 https://reactome.org/PathwayBrowser/#/R-HSA-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 TAS Homo sapiens 57856 R-HSA-5661126 https://reactome.org/PathwayBrowser/#/R-HSA-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 TAS Homo sapiens 57856 R-HSA-5676966 https://reactome.org/PathwayBrowser/#/R-HSA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp TAS Homo sapiens 57856 R-HSA-5682965 https://reactome.org/PathwayBrowser/#/R-HSA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs TAS Homo sapiens 57856 R-HSA-5696213 https://reactome.org/PathwayBrowser/#/R-HSA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite TAS Homo sapiens 57856 R-HSA-5696220 https://reactome.org/PathwayBrowser/#/R-HSA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) TAS Homo sapiens 57856 R-HSA-6782286 https://reactome.org/PathwayBrowser/#/R-HSA-6782286 METTL1:WDR4 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 IEA Homo sapiens 57856 R-HSA-6782388 https://reactome.org/PathwayBrowser/#/R-HSA-6782388 NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) IEA Homo sapiens 57856 R-HSA-6782416 https://reactome.org/PathwayBrowser/#/R-HSA-6782416 TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) TAS Homo sapiens 57856 R-HSA-6782419 https://reactome.org/PathwayBrowser/#/R-HSA-6782419 TRDMT1 (DNMT2) methylates cytidine-38 of tRNA(Asp) TAS Homo sapiens 57856 R-HSA-6782859 https://reactome.org/PathwayBrowser/#/R-HSA-6782859 TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 57856 R-HSA-6782879 https://reactome.org/PathwayBrowser/#/R-HSA-6782879 TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 57856 R-HSA-6782881 https://reactome.org/PathwayBrowser/#/R-HSA-6782881 LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 57856 R-HSA-6782890 https://reactome.org/PathwayBrowser/#/R-HSA-6782890 LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 57856 R-HSA-6783473 https://reactome.org/PathwayBrowser/#/R-HSA-6783473 LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 57856 R-HSA-6783492 https://reactome.org/PathwayBrowser/#/R-HSA-6783492 TRMT6:TRMT61A methylate adenosine yielding 1-methyladenosine at nucleotide 58 of tRNA(Met) TAS Homo sapiens 57856 R-HSA-6785409 https://reactome.org/PathwayBrowser/#/R-HSA-6785409 NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) IEA Homo sapiens 57856 R-HSA-6785438 https://reactome.org/PathwayBrowser/#/R-HSA-6785438 NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) TAS Homo sapiens 57856 R-HSA-6786205 https://reactome.org/PathwayBrowser/#/R-HSA-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 TAS Homo sapiens 57856 R-HSA-6786500 https://reactome.org/PathwayBrowser/#/R-HSA-6786500 ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 IEA Homo sapiens 57856 R-HSA-6786501 https://reactome.org/PathwayBrowser/#/R-HSA-6786501 TRMT11:TRMT112 methylates guanosine-10 in tRNA IEA Homo sapiens 57856 R-HSA-6786567 https://reactome.org/PathwayBrowser/#/R-HSA-6786567 KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine TAS Homo sapiens 57856 R-HSA-6786571 https://reactome.org/PathwayBrowser/#/R-HSA-6786571 CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37 TAS Homo sapiens 57856 R-HSA-6786621 https://reactome.org/PathwayBrowser/#/R-HSA-6786621 TRMT10A methylates guanosine-9 in tRNA IEA Homo sapiens 57856 R-HSA-6787525 https://reactome.org/PathwayBrowser/#/R-HSA-6787525 TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58 TAS Homo sapiens 57856 R-HSA-6787591 https://reactome.org/PathwayBrowser/#/R-HSA-6787591 TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9 TAS Homo sapiens 57856 R-HSA-6787594 https://reactome.org/PathwayBrowser/#/R-HSA-6787594 TRMT10C:HSD17B10 (TRMT10C:SDR5C1) methylates adenosine-9 in tRNA yielding 1-methyladenosine-9 TAS Homo sapiens 57856 R-HSA-6788650 https://reactome.org/PathwayBrowser/#/R-HSA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins TAS Homo sapiens 57856 R-HSA-6788668 https://reactome.org/PathwayBrowser/#/R-HSA-6788668 TRMT13 2'-O-methylates adenosine-4 in tRNA IEA Homo sapiens 57856 R-HSA-6788684 https://reactome.org/PathwayBrowser/#/R-HSA-6788684 TRMT13 2'-O-methylates cytidine-4 in tRNA IEA Homo sapiens 57856 R-HSA-6788707 https://reactome.org/PathwayBrowser/#/R-HSA-6788707 TRMT44 2'-O-methylates uridine-44 in tRNA(Ser) IEA Homo sapiens 57856 R-HSA-6790906 https://reactome.org/PathwayBrowser/#/R-HSA-6790906 EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 IEA Homo sapiens 57856 R-HSA-6790907 https://reactome.org/PathwayBrowser/#/R-HSA-6790907 Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides IEA Homo sapiens 57856 R-HSA-6790944 https://reactome.org/PathwayBrowser/#/R-HSA-6790944 NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447 IEA Homo sapiens 57856 R-HSA-6790982 https://reactome.org/PathwayBrowser/#/R-HSA-6790982 WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639 TAS Homo sapiens 57856 R-HSA-6790994 https://reactome.org/PathwayBrowser/#/R-HSA-6790994 DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851 TAS Homo sapiens 57856 R-HSA-6793057 https://reactome.org/PathwayBrowser/#/R-HSA-6793057 NSUN4 methylates cytidine-841 of 12S rRNA yielding 5-methylcytidine-841 TAS Homo sapiens 57856 R-HSA-6793066 https://reactome.org/PathwayBrowser/#/R-HSA-6793066 TFB1M dimethylates adenosine-936 and adenosine-937 of 12S rRNA yielding 6-dimethyladenosine-936 and 6-dimethyladenosine-937 TAS Homo sapiens 57856 R-HSA-6793096 https://reactome.org/PathwayBrowser/#/R-HSA-6793096 MRM3 (RNMTL1) methylates guanosine-1370 of 16S rRNA yielding 2'-O-methylguanosine-1370 TAS Homo sapiens 57856 R-HSA-6793122 https://reactome.org/PathwayBrowser/#/R-HSA-6793122 MRM1 methylates guanosine-1145 of 16S rRNA yielding 2'-O-methylguanosine-1145 TAS Homo sapiens 57856 R-HSA-6793127 https://reactome.org/PathwayBrowser/#/R-HSA-6793127 MRM2 (FTSJ2) methylates uridine-1369 of 16S rRNA yielding 2'-O-methyluridine TAS Homo sapiens 57856 R-HSA-6798317 https://reactome.org/PathwayBrowser/#/R-HSA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC TAS Homo sapiens 57856 R-HSA-6800138 https://reactome.org/PathwayBrowser/#/R-HSA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer TAS Homo sapiens 57856 R-HSA-6800149 https://reactome.org/PathwayBrowser/#/R-HSA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII TAS Homo sapiens 57856 R-HSA-6804383 https://reactome.org/PathwayBrowser/#/R-HSA-6804383 PRMT5 methylates TP53 TAS Homo sapiens 57856 R-HSA-6805730 https://reactome.org/PathwayBrowser/#/R-HSA-6805730 SETD9 methylates TP53 TAS Homo sapiens 57856 R-HSA-6805740 https://reactome.org/PathwayBrowser/#/R-HSA-6805740 SETD8 methylates TP53 TAS Homo sapiens 57856 R-HSA-6805755 https://reactome.org/PathwayBrowser/#/R-HSA-6805755 EHMT1:EHMT2 dimethylates TP53 TAS Homo sapiens 57856 R-HSA-71286 https://reactome.org/PathwayBrowser/#/R-HSA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine TAS Homo sapiens 57856 R-HSA-77090 https://reactome.org/PathwayBrowser/#/R-HSA-77090 Methylation of GMP-cap by RNA Methyltransferase TAS Homo sapiens 57856 R-HSA-8855062 https://reactome.org/PathwayBrowser/#/R-HSA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy TAS Homo sapiens 57856 R-HSA-8856945 https://reactome.org/PathwayBrowser/#/R-HSA-8856945 PP2A methylation by LCMT1 TAS Homo sapiens 57856 R-HSA-8865237 https://reactome.org/PathwayBrowser/#/R-HSA-8865237 SETD6 methylates RELA in the NFkB complex TAS Homo sapiens 57856 R-HSA-8865498 https://reactome.org/PathwayBrowser/#/R-HSA-8865498 KMT2A trimethylates nucleosomes at the SPI1 gene locus producing H3K4Me3 mark IEA Homo sapiens 57856 R-HSA-8876789 https://reactome.org/PathwayBrowser/#/R-HSA-8876789 CARNMT1 methylates CARN to Anserine TAS Homo sapiens 57856 R-HSA-8879123 https://reactome.org/PathwayBrowser/#/R-HSA-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 TAS Homo sapiens 57856 R-HSA-8931858 https://reactome.org/PathwayBrowser/#/R-HSA-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB TAS Homo sapiens 57856 R-HSA-8931974 https://reactome.org/PathwayBrowser/#/R-HSA-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A TAS Homo sapiens 57856 R-HSA-8932221 https://reactome.org/PathwayBrowser/#/R-HSA-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 TAS Homo sapiens 57856 R-HSA-8932243 https://reactome.org/PathwayBrowser/#/R-HSA-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 TAS Homo sapiens 57856 R-HSA-8932275 https://reactome.org/PathwayBrowser/#/R-HSA-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN TAS Homo sapiens 57856 R-HSA-8932276 https://reactome.org/PathwayBrowser/#/R-HSA-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP TAS Homo sapiens 57856 R-HSA-8932413 https://reactome.org/PathwayBrowser/#/R-HSA-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 TAS Homo sapiens 57856 R-HSA-8932765 https://reactome.org/PathwayBrowser/#/R-HSA-8932765 NSUN6 methylates cytidine-72 in tRNA(Cys) and tRNA(Thr) TAS Homo sapiens 57856 R-HSA-8934735 https://reactome.org/PathwayBrowser/#/R-HSA-8934735 PRMT1 arginine-methylates RUNX1 TAS Homo sapiens 57856 R-HSA-8936481 https://reactome.org/PathwayBrowser/#/R-HSA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter TAS Homo sapiens 57856 R-HSA-8936584 https://reactome.org/PathwayBrowser/#/R-HSA-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter TAS Homo sapiens 57856 R-HSA-8936608 https://reactome.org/PathwayBrowser/#/R-HSA-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter TAS Homo sapiens 57856 R-HSA-8936621 https://reactome.org/PathwayBrowser/#/R-HSA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter TAS Homo sapiens 57856 R-HSA-8937016 https://reactome.org/PathwayBrowser/#/R-HSA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter TAS Homo sapiens 57856 R-HSA-8937022 https://reactome.org/PathwayBrowser/#/R-HSA-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter TAS Homo sapiens 57856 R-HSA-8937050 https://reactome.org/PathwayBrowser/#/R-HSA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter TAS Homo sapiens 57856 R-HSA-8937113 https://reactome.org/PathwayBrowser/#/R-HSA-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter TAS Homo sapiens 57856 R-HSA-8955010 https://reactome.org/PathwayBrowser/#/R-HSA-8955010 LRTOMT transfers Met to DA, forming 3MT TAS Homo sapiens 57856 R-HSA-9024159 https://reactome.org/PathwayBrowser/#/R-HSA-9024159 FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe) TAS Homo sapiens 57856 R-HSA-9024161 https://reactome.org/PathwayBrowser/#/R-HSA-9024161 FTSJ1 2'-O-methylates guanosine-34 in tRNA(Phe) TAS Homo sapiens 57856 R-HSA-9632182 https://reactome.org/PathwayBrowser/#/R-HSA-9632182 PRMT1 methylates ESRs TAS Homo sapiens 57856 R-HSA-9647977 https://reactome.org/PathwayBrowser/#/R-HSA-9647977 ICMT methylates S-Farn RAS proteins TAS Homo sapiens 57856 R-HSA-9684016 https://reactome.org/PathwayBrowser/#/R-HSA-9684016 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 57856 R-HSA-9684017 https://reactome.org/PathwayBrowser/#/R-HSA-9684017 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 57856 R-HSA-9684018 https://reactome.org/PathwayBrowser/#/R-HSA-9684018 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 57856 R-HSA-9684030 https://reactome.org/PathwayBrowser/#/R-HSA-9684030 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 57856 R-HSA-9684032 https://reactome.org/PathwayBrowser/#/R-HSA-9684032 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 57856 R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 57856 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 57856 R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 57856 R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 57856 R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 57856 R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 57856 R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 57856 R-HSA-9710490 https://reactome.org/PathwayBrowser/#/R-HSA-9710490 The GSDME gene promoter is hypermethylated TAS Homo sapiens 57856 R-HSA-9729283 https://reactome.org/PathwayBrowser/#/R-HSA-9729283 Nucleoprotein is methylated by PRMT1 TAS Homo sapiens 57856 R-HSA-9748979 https://reactome.org/PathwayBrowser/#/R-HSA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP TAS Homo sapiens 57856 R-HSA-9748983 https://reactome.org/PathwayBrowser/#/R-HSA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP TAS Homo sapiens 57856 R-HSA-9822583 https://reactome.org/PathwayBrowser/#/R-HSA-9822583 METTL23 dimethylates histone H3.3 arginine-17 (arginine-18 in the preprotein) IEA Homo sapiens 57856 R-HSA-9830848 https://reactome.org/PathwayBrowser/#/R-HSA-9830848 L protein acts as a cap N7 methyltransferase to modify RSV mRNAs TAS Homo sapiens 57856 R-HSA-9834003 https://reactome.org/PathwayBrowser/#/R-HSA-9834003 L protein acts as a cap 2'-O-methyltransferase to modify RSV mRNAs TAS Homo sapiens 57856 R-HSA-9854315 https://reactome.org/PathwayBrowser/#/R-HSA-9854315 CSKMT methylates Citrate Synthase TAS Homo sapiens 57856 R-MMU-1214198 https://reactome.org/PathwayBrowser/#/R-MMU-1214198 Prdm9 Trimethylates Histone H3 at Lysine-4 TAS Mus musculus 57856 R-MMU-1483174 https://reactome.org/PathwayBrowser/#/R-MMU-1483174 PE is methylated to PC by PEMT IEA Mus musculus 57856 R-MMU-158609 https://reactome.org/PathwayBrowser/#/R-MMU-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Mus musculus 57856 R-MMU-174401 https://reactome.org/PathwayBrowser/#/R-MMU-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Mus musculus 57856 R-MMU-175983 https://reactome.org/PathwayBrowser/#/R-MMU-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Mus musculus 57856 R-MMU-175987 https://reactome.org/PathwayBrowser/#/R-MMU-175987 NNMT transfers CH3 from AdoMet to PY IEA Mus musculus 57856 R-MMU-209821 https://reactome.org/PathwayBrowser/#/R-MMU-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Mus musculus 57856 R-MMU-209903 https://reactome.org/PathwayBrowser/#/R-MMU-209903 Noradrenaline is converted to adrenaline IEA Mus musculus 57856 R-MMU-212263 https://reactome.org/PathwayBrowser/#/R-MMU-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Mus musculus 57856 R-MMU-212269 https://reactome.org/PathwayBrowser/#/R-MMU-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Mus musculus 57856 R-MMU-2162186 https://reactome.org/PathwayBrowser/#/R-MMU-2162186 COQ3 methylates DeMQ10H2 IEA Mus musculus 57856 R-MMU-2162188 https://reactome.org/PathwayBrowser/#/R-MMU-2162188 COQ5 methylates MDMQ10H2 IEA Mus musculus 57856 R-MMU-2162193 https://reactome.org/PathwayBrowser/#/R-MMU-2162193 COQ3 methylates DHDB IEA Mus musculus 57856 R-MMU-2408549 https://reactome.org/PathwayBrowser/#/R-MMU-2408549 Me2Se is methylated to Me3Se+ by Inmt TAS Mus musculus 57856 R-MMU-3149518 https://reactome.org/PathwayBrowser/#/R-MMU-3149518 MTRR reduces cob(II)alamin to meCbl IEA Mus musculus 57856 R-MMU-3222237 https://reactome.org/PathwayBrowser/#/R-MMU-3222237 SMYD2 methylates TP53 IEA Mus musculus 57856 R-MMU-379387 https://reactome.org/PathwayBrowser/#/R-MMU-379387 COMT transfers Met to DA to form 3MT IEA Mus musculus 57856 R-MMU-4827382 https://reactome.org/PathwayBrowser/#/R-MMU-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Mus musculus 57856 R-MMU-4827383 https://reactome.org/PathwayBrowser/#/R-MMU-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Mus musculus 57856 R-MMU-5159245 https://reactome.org/PathwayBrowser/#/R-MMU-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Mus musculus 57856 R-MMU-5205798 https://reactome.org/PathwayBrowser/#/R-MMU-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Mus musculus 57856 R-MMU-5205799 https://reactome.org/PathwayBrowser/#/R-MMU-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Mus musculus 57856 R-MMU-5205820 https://reactome.org/PathwayBrowser/#/R-MMU-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Mus musculus 57856 R-MMU-5205822 https://reactome.org/PathwayBrowser/#/R-MMU-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 IEA Mus musculus 57856 R-MMU-5205824 https://reactome.org/PathwayBrowser/#/R-MMU-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Mus musculus 57856 R-MMU-5205861 https://reactome.org/PathwayBrowser/#/R-MMU-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Mus musculus 57856 R-MMU-5205867 https://reactome.org/PathwayBrowser/#/R-MMU-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Mus musculus 57856 R-MMU-5218952 https://reactome.org/PathwayBrowser/#/R-MMU-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Mus musculus 57856 R-MMU-5229010 https://reactome.org/PathwayBrowser/#/R-MMU-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) IEA Mus musculus 57856 R-MMU-5229203 https://reactome.org/PathwayBrowser/#/R-MMU-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Mus musculus 57856 R-MMU-5244692 https://reactome.org/PathwayBrowser/#/R-MMU-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Mus musculus 57856 R-MMU-5336316 https://reactome.org/PathwayBrowser/#/R-MMU-5336316 Dnmt3a:Dnmt3l methylates cytosine in DNA TAS Mus musculus 57856 R-MMU-5336369 https://reactome.org/PathwayBrowser/#/R-MMU-5336369 Dnmt1 methylates cytosine in hemimethylated DNA TAS Mus musculus 57856 R-MMU-5336380 https://reactome.org/PathwayBrowser/#/R-MMU-5336380 Dnmt3b:Dnmt3l methylates cytosine in DNA TAS Mus musculus 57856 R-MMU-5358484 https://reactome.org/PathwayBrowser/#/R-MMU-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Mus musculus 57856 R-MMU-5359451 https://reactome.org/PathwayBrowser/#/R-MMU-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Mus musculus 57856 R-MMU-5423038 https://reactome.org/PathwayBrowser/#/R-MMU-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Mus musculus 57856 R-MMU-5629217 https://reactome.org/PathwayBrowser/#/R-MMU-5629217 Henmt1 methylates 2' hydroxyl at 3' end of piRNA in Asz1:Ddx4:Mov10l1:6xMeR-Piwil2:piRNA:Tdrd1:Tdrd12 TAS Mus musculus 57856 R-MMU-5629230 https://reactome.org/PathwayBrowser/#/R-MMU-5629230 Henmt1 methylates 2' hydroxyl at 3' end of piRNA in MeR-Piwil4:piRNA:Tdrd9:Mael:Tdrkh TAS Mus musculus 57856 R-MMU-5629239 https://reactome.org/PathwayBrowser/#/R-MMU-5629239 Henmt1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-Piwil1:piRNA:Tdrd6:Tdrkh TAS Mus musculus 57856 R-MMU-5634729 https://reactome.org/PathwayBrowser/#/R-MMU-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Mus musculus 57856 R-MMU-5634750 https://reactome.org/PathwayBrowser/#/R-MMU-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Mus musculus 57856 R-MMU-5634802 https://reactome.org/PathwayBrowser/#/R-MMU-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Mus musculus 57856 R-MMU-5637686 https://reactome.org/PathwayBrowser/#/R-MMU-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Mus musculus 57856 R-MMU-5638141 https://reactome.org/PathwayBrowser/#/R-MMU-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) IEA Mus musculus 57856 R-MMU-5638157 https://reactome.org/PathwayBrowser/#/R-MMU-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Mus musculus 57856 R-MMU-5638332 https://reactome.org/PathwayBrowser/#/R-MMU-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Mus musculus 57856 R-MMU-5638333 https://reactome.org/PathwayBrowser/#/R-MMU-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Mus musculus 57856 R-MMU-5649764 https://reactome.org/PathwayBrowser/#/R-MMU-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Mus musculus 57856 R-MMU-5649799 https://reactome.org/PathwayBrowser/#/R-MMU-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Mus musculus 57856 R-MMU-5649800 https://reactome.org/PathwayBrowser/#/R-MMU-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Mus musculus 57856 R-MMU-5649801 https://reactome.org/PathwayBrowser/#/R-MMU-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Mus musculus 57856 R-MMU-5649802 https://reactome.org/PathwayBrowser/#/R-MMU-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Mus musculus 57856 R-MMU-5651654 https://reactome.org/PathwayBrowser/#/R-MMU-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Mus musculus 57856 R-MMU-5651657 https://reactome.org/PathwayBrowser/#/R-MMU-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Mus musculus 57856 R-MMU-5661117 https://reactome.org/PathwayBrowser/#/R-MMU-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Mus musculus 57856 R-MMU-5661126 https://reactome.org/PathwayBrowser/#/R-MMU-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Mus musculus 57856 R-MMU-5676966 https://reactome.org/PathwayBrowser/#/R-MMU-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Mus musculus 57856 R-MMU-5682965 https://reactome.org/PathwayBrowser/#/R-MMU-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Mus musculus 57856 R-MMU-5696213 https://reactome.org/PathwayBrowser/#/R-MMU-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Mus musculus 57856 R-MMU-5696220 https://reactome.org/PathwayBrowser/#/R-MMU-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Mus musculus 57856 R-MMU-573376 https://reactome.org/PathwayBrowser/#/R-MMU-573376 NoRC:intergenic spacer:Hdac:Dnmt complex deacetylates histone H4 and dimethylates lysine-9 of histone H3 in main promoter of the rRNA gene TAS Mus musculus 57856 R-MMU-573383 https://reactome.org/PathwayBrowser/#/R-MMU-573383 NoRC:intergenic spacer:Hdac:Dnmt complex methylates cytosine in the rRNA genes TAS Mus musculus 57856 R-MMU-6786205 https://reactome.org/PathwayBrowser/#/R-MMU-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Mus musculus 57856 R-MMU-6788650 https://reactome.org/PathwayBrowser/#/R-MMU-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Mus musculus 57856 R-MMU-6798317 https://reactome.org/PathwayBrowser/#/R-MMU-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Mus musculus 57856 R-MMU-6800138 https://reactome.org/PathwayBrowser/#/R-MMU-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Mus musculus 57856 R-MMU-6800149 https://reactome.org/PathwayBrowser/#/R-MMU-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Mus musculus 57856 R-MMU-6804383 https://reactome.org/PathwayBrowser/#/R-MMU-6804383 PRMT5 methylates TP53 IEA Mus musculus 57856 R-MMU-6805740 https://reactome.org/PathwayBrowser/#/R-MMU-6805740 SETD8 methylates TP53 IEA Mus musculus 57856 R-MMU-6805755 https://reactome.org/PathwayBrowser/#/R-MMU-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Mus musculus 57856 R-MMU-71286 https://reactome.org/PathwayBrowser/#/R-MMU-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Mus musculus 57856 R-MMU-77090 https://reactome.org/PathwayBrowser/#/R-MMU-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Mus musculus 57856 R-MMU-8855062 https://reactome.org/PathwayBrowser/#/R-MMU-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Mus musculus 57856 R-MMU-8856945 https://reactome.org/PathwayBrowser/#/R-MMU-8856945 PP2A methylation by LCMT1 IEA Mus musculus 57856 R-MMU-8865237 https://reactome.org/PathwayBrowser/#/R-MMU-8865237 SETD6 methylates RELA in the NFkB complex IEA Mus musculus 57856 R-MMU-8876789 https://reactome.org/PathwayBrowser/#/R-MMU-8876789 CARNMT1 methylates CARN to Anserine IEA Mus musculus 57856 R-MMU-8879123 https://reactome.org/PathwayBrowser/#/R-MMU-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Mus musculus 57856 R-MMU-8931858 https://reactome.org/PathwayBrowser/#/R-MMU-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Mus musculus 57856 R-MMU-8931974 https://reactome.org/PathwayBrowser/#/R-MMU-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Mus musculus 57856 R-MMU-8932221 https://reactome.org/PathwayBrowser/#/R-MMU-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Mus musculus 57856 R-MMU-8932243 https://reactome.org/PathwayBrowser/#/R-MMU-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Mus musculus 57856 R-MMU-8932275 https://reactome.org/PathwayBrowser/#/R-MMU-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Mus musculus 57856 R-MMU-8932276 https://reactome.org/PathwayBrowser/#/R-MMU-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Mus musculus 57856 R-MMU-8932413 https://reactome.org/PathwayBrowser/#/R-MMU-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Mus musculus 57856 R-MMU-8934735 https://reactome.org/PathwayBrowser/#/R-MMU-8934735 PRMT1 arginine-methylates RUNX1 IEA Mus musculus 57856 R-MMU-8936481 https://reactome.org/PathwayBrowser/#/R-MMU-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Mus musculus 57856 R-MMU-8936584 https://reactome.org/PathwayBrowser/#/R-MMU-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Mus musculus 57856 R-MMU-8936608 https://reactome.org/PathwayBrowser/#/R-MMU-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Mus musculus 57856 R-MMU-8936621 https://reactome.org/PathwayBrowser/#/R-MMU-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Mus musculus 57856 R-MMU-8937016 https://reactome.org/PathwayBrowser/#/R-MMU-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Mus musculus 57856 R-MMU-8937022 https://reactome.org/PathwayBrowser/#/R-MMU-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Mus musculus 57856 R-MMU-8937050 https://reactome.org/PathwayBrowser/#/R-MMU-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Mus musculus 57856 R-MMU-8937113 https://reactome.org/PathwayBrowser/#/R-MMU-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Mus musculus 57856 R-MMU-8955010 https://reactome.org/PathwayBrowser/#/R-MMU-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Mus musculus 57856 R-MMU-9632182 https://reactome.org/PathwayBrowser/#/R-MMU-9632182 PRMT1 methylates ESRs IEA Mus musculus 57856 R-MMU-9647977 https://reactome.org/PathwayBrowser/#/R-MMU-9647977 ICMT methylates S-Farn RAS proteins IEA Mus musculus 57856 R-MMU-9748979 https://reactome.org/PathwayBrowser/#/R-MMU-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Mus musculus 57856 R-MMU-9748983 https://reactome.org/PathwayBrowser/#/R-MMU-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Mus musculus 57856 R-MMU-9822592 https://reactome.org/PathwayBrowser/#/R-MMU-9822592 Mettl23 dimethylates histone H3.3 arginine-18 (arginine-17 in the mature protein) TAS Mus musculus 57856 R-NUL-1214205 https://reactome.org/PathwayBrowser/#/R-NUL-1214205 Prdm9 Trimethylates Histone H3 (murine, bovine) TAS Bos taurus 57856 R-NUL-573373 https://reactome.org/PathwayBrowser/#/R-NUL-573373 Ttf-I:rRNA Promoter:Ercc6:Ehmt2 complex dimethylates histone H3 at lysine-9 TAS Homo sapiens 57856 R-NUL-8865525 https://reactome.org/PathwayBrowser/#/R-NUL-8865525 KTM2A trimethylates nucleosomes at the Spi1 gene locus producing H3K4Me3 mark TAS Homo sapiens 57856 R-PFA-2301205 https://reactome.org/PathwayBrowser/#/R-PFA-2301205 SETD8 monomethylates histone H4 IEA Plasmodium falciparum 57856 R-PFA-4827383 https://reactome.org/PathwayBrowser/#/R-PFA-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Plasmodium falciparum 57856 R-PFA-5159245 https://reactome.org/PathwayBrowser/#/R-PFA-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Plasmodium falciparum 57856 R-PFA-5205798 https://reactome.org/PathwayBrowser/#/R-PFA-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Plasmodium falciparum 57856 R-PFA-5205867 https://reactome.org/PathwayBrowser/#/R-PFA-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Plasmodium falciparum 57856 R-PFA-5218952 https://reactome.org/PathwayBrowser/#/R-PFA-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Plasmodium falciparum 57856 R-PFA-5244692 https://reactome.org/PathwayBrowser/#/R-PFA-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Plasmodium falciparum 57856 R-PFA-5358484 https://reactome.org/PathwayBrowser/#/R-PFA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Plasmodium falciparum 57856 R-PFA-5423038 https://reactome.org/PathwayBrowser/#/R-PFA-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Plasmodium falciparum 57856 R-PFA-5637686 https://reactome.org/PathwayBrowser/#/R-PFA-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Plasmodium falciparum 57856 R-PFA-5638157 https://reactome.org/PathwayBrowser/#/R-PFA-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Plasmodium falciparum 57856 R-PFA-5638333 https://reactome.org/PathwayBrowser/#/R-PFA-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Plasmodium falciparum 57856 R-PFA-5649800 https://reactome.org/PathwayBrowser/#/R-PFA-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Plasmodium falciparum 57856 R-PFA-5649802 https://reactome.org/PathwayBrowser/#/R-PFA-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Plasmodium falciparum 57856 R-PFA-5661126 https://reactome.org/PathwayBrowser/#/R-PFA-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Plasmodium falciparum 57856 R-PFA-5676966 https://reactome.org/PathwayBrowser/#/R-PFA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Plasmodium falciparum 57856 R-PFA-6788650 https://reactome.org/PathwayBrowser/#/R-PFA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Plasmodium falciparum 57856 R-PFA-6800138 https://reactome.org/PathwayBrowser/#/R-PFA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Plasmodium falciparum 57856 R-PFA-6800149 https://reactome.org/PathwayBrowser/#/R-PFA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Plasmodium falciparum 57856 R-PFA-8855062 https://reactome.org/PathwayBrowser/#/R-PFA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Plasmodium falciparum 57856 R-PFA-8876789 https://reactome.org/PathwayBrowser/#/R-PFA-8876789 CARNMT1 methylates CARN to Anserine IEA Plasmodium falciparum 57856 R-PFA-8879123 https://reactome.org/PathwayBrowser/#/R-PFA-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Plasmodium falciparum 57856 R-PFA-8932413 https://reactome.org/PathwayBrowser/#/R-PFA-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Plasmodium falciparum 57856 R-RNO-1483174 https://reactome.org/PathwayBrowser/#/R-RNO-1483174 PE is methylated to PC by PEMT IEA Rattus norvegicus 57856 R-RNO-158609 https://reactome.org/PathwayBrowser/#/R-RNO-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Rattus norvegicus 57856 R-RNO-174401 https://reactome.org/PathwayBrowser/#/R-RNO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Rattus norvegicus 57856 R-RNO-175983 https://reactome.org/PathwayBrowser/#/R-RNO-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Rattus norvegicus 57856 R-RNO-175987 https://reactome.org/PathwayBrowser/#/R-RNO-175987 NNMT transfers CH3 from AdoMet to PY IEA Rattus norvegicus 57856 R-RNO-209821 https://reactome.org/PathwayBrowser/#/R-RNO-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Rattus norvegicus 57856 R-RNO-209903 https://reactome.org/PathwayBrowser/#/R-RNO-209903 Noradrenaline is converted to adrenaline IEA Rattus norvegicus 57856 R-RNO-212263 https://reactome.org/PathwayBrowser/#/R-RNO-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Rattus norvegicus 57856 R-RNO-212269 https://reactome.org/PathwayBrowser/#/R-RNO-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Rattus norvegicus 57856 R-RNO-2162186 https://reactome.org/PathwayBrowser/#/R-RNO-2162186 COQ3 methylates DeMQ10H2 IEA Rattus norvegicus 57856 R-RNO-2162188 https://reactome.org/PathwayBrowser/#/R-RNO-2162188 COQ5 methylates MDMQ10H2 IEA Rattus norvegicus 57856 R-RNO-2162193 https://reactome.org/PathwayBrowser/#/R-RNO-2162193 COQ3 methylates DHDB IEA Rattus norvegicus 57856 R-RNO-2301205 https://reactome.org/PathwayBrowser/#/R-RNO-2301205 SETD8 monomethylates histone H4 IEA Rattus norvegicus 57856 R-RNO-2408501 https://reactome.org/PathwayBrowser/#/R-RNO-2408501 MeSeH is methylated to Me2Se by MeSeH methyltransferase TAS Rattus norvegicus 57856 R-RNO-2408511 https://reactome.org/PathwayBrowser/#/R-RNO-2408511 H2Se is methylated to MeSeH by H2Se methyltransferase TAS Rattus norvegicus 57856 R-RNO-3149518 https://reactome.org/PathwayBrowser/#/R-RNO-3149518 MTRR reduces cob(II)alamin to meCbl IEA Rattus norvegicus 57856 R-RNO-3222237 https://reactome.org/PathwayBrowser/#/R-RNO-3222237 SMYD2 methylates TP53 IEA Rattus norvegicus 57856 R-RNO-3240295 https://reactome.org/PathwayBrowser/#/R-RNO-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Rattus norvegicus 57856 R-RNO-3788745 https://reactome.org/PathwayBrowser/#/R-RNO-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Rattus norvegicus 57856 R-RNO-3788748 https://reactome.org/PathwayBrowser/#/R-RNO-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Rattus norvegicus 57856 R-RNO-379387 https://reactome.org/PathwayBrowser/#/R-RNO-379387 COMT transfers Met to DA to form 3MT IEA Rattus norvegicus 57856 R-RNO-427527 https://reactome.org/PathwayBrowser/#/R-RNO-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Rattus norvegicus 57856 R-RNO-4827382 https://reactome.org/PathwayBrowser/#/R-RNO-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Rattus norvegicus 57856 R-RNO-4827383 https://reactome.org/PathwayBrowser/#/R-RNO-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Rattus norvegicus 57856 R-RNO-5159245 https://reactome.org/PathwayBrowser/#/R-RNO-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus 57856 R-RNO-5205798 https://reactome.org/PathwayBrowser/#/R-RNO-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Rattus norvegicus 57856 R-RNO-5205799 https://reactome.org/PathwayBrowser/#/R-RNO-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Rattus norvegicus 57856 R-RNO-5205822 https://reactome.org/PathwayBrowser/#/R-RNO-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 IEA Rattus norvegicus 57856 R-RNO-5205824 https://reactome.org/PathwayBrowser/#/R-RNO-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Rattus norvegicus 57856 R-RNO-5205861 https://reactome.org/PathwayBrowser/#/R-RNO-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Rattus norvegicus 57856 R-RNO-5205867 https://reactome.org/PathwayBrowser/#/R-RNO-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Rattus norvegicus 57856 R-RNO-5218952 https://reactome.org/PathwayBrowser/#/R-RNO-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Rattus norvegicus 57856 R-RNO-5229010 https://reactome.org/PathwayBrowser/#/R-RNO-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) IEA Rattus norvegicus 57856 R-RNO-5244692 https://reactome.org/PathwayBrowser/#/R-RNO-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus 57856 R-RNO-5333614 https://reactome.org/PathwayBrowser/#/R-RNO-5333614 GSSebGalNac is reduced and methylated to MeSebGalNac TAS Rattus norvegicus 57856 R-RNO-5358484 https://reactome.org/PathwayBrowser/#/R-RNO-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Rattus norvegicus 57856 R-RNO-5359451 https://reactome.org/PathwayBrowser/#/R-RNO-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Rattus norvegicus 57856 R-RNO-5423038 https://reactome.org/PathwayBrowser/#/R-RNO-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Rattus norvegicus 57856 R-RNO-5634729 https://reactome.org/PathwayBrowser/#/R-RNO-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Rattus norvegicus 57856 R-RNO-5634750 https://reactome.org/PathwayBrowser/#/R-RNO-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Rattus norvegicus 57856 R-RNO-5634802 https://reactome.org/PathwayBrowser/#/R-RNO-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Rattus norvegicus 57856 R-RNO-5637686 https://reactome.org/PathwayBrowser/#/R-RNO-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus 57856 R-RNO-5638141 https://reactome.org/PathwayBrowser/#/R-RNO-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) IEA Rattus norvegicus 57856 R-RNO-5638157 https://reactome.org/PathwayBrowser/#/R-RNO-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Rattus norvegicus 57856 R-RNO-5638332 https://reactome.org/PathwayBrowser/#/R-RNO-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Rattus norvegicus 57856 R-RNO-5638333 https://reactome.org/PathwayBrowser/#/R-RNO-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Rattus norvegicus 57856 R-RNO-5649764 https://reactome.org/PathwayBrowser/#/R-RNO-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Rattus norvegicus 57856 R-RNO-5649799 https://reactome.org/PathwayBrowser/#/R-RNO-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Rattus norvegicus 57856 R-RNO-5649800 https://reactome.org/PathwayBrowser/#/R-RNO-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Rattus norvegicus 57856 R-RNO-5649801 https://reactome.org/PathwayBrowser/#/R-RNO-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Rattus norvegicus 57856 R-RNO-5649802 https://reactome.org/PathwayBrowser/#/R-RNO-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Rattus norvegicus 57856 R-RNO-5651654 https://reactome.org/PathwayBrowser/#/R-RNO-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Rattus norvegicus 57856 R-RNO-5651657 https://reactome.org/PathwayBrowser/#/R-RNO-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Rattus norvegicus 57856 R-RNO-5661117 https://reactome.org/PathwayBrowser/#/R-RNO-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Rattus norvegicus 57856 R-RNO-5661126 https://reactome.org/PathwayBrowser/#/R-RNO-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Rattus norvegicus 57856 R-RNO-5676966 https://reactome.org/PathwayBrowser/#/R-RNO-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Rattus norvegicus 57856 R-RNO-5682965 https://reactome.org/PathwayBrowser/#/R-RNO-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Rattus norvegicus 57856 R-RNO-5696213 https://reactome.org/PathwayBrowser/#/R-RNO-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Rattus norvegicus 57856 R-RNO-5696220 https://reactome.org/PathwayBrowser/#/R-RNO-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Rattus norvegicus 57856 R-RNO-6786205 https://reactome.org/PathwayBrowser/#/R-RNO-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Rattus norvegicus 57856 R-RNO-6788650 https://reactome.org/PathwayBrowser/#/R-RNO-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Rattus norvegicus 57856 R-RNO-6798317 https://reactome.org/PathwayBrowser/#/R-RNO-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Rattus norvegicus 57856 R-RNO-6804383 https://reactome.org/PathwayBrowser/#/R-RNO-6804383 PRMT5 methylates TP53 IEA Rattus norvegicus 57856 R-RNO-6805740 https://reactome.org/PathwayBrowser/#/R-RNO-6805740 SETD8 methylates TP53 IEA Rattus norvegicus 57856 R-RNO-6805755 https://reactome.org/PathwayBrowser/#/R-RNO-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Rattus norvegicus 57856 R-RNO-71286 https://reactome.org/PathwayBrowser/#/R-RNO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Rattus norvegicus 57856 R-RNO-77090 https://reactome.org/PathwayBrowser/#/R-RNO-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Rattus norvegicus 57856 R-RNO-8855062 https://reactome.org/PathwayBrowser/#/R-RNO-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Rattus norvegicus 57856 R-RNO-8856945 https://reactome.org/PathwayBrowser/#/R-RNO-8856945 PP2A methylation by LCMT1 IEA Rattus norvegicus 57856 R-RNO-8865237 https://reactome.org/PathwayBrowser/#/R-RNO-8865237 SETD6 methylates RELA in the NFkB complex IEA Rattus norvegicus 57856 R-RNO-8876789 https://reactome.org/PathwayBrowser/#/R-RNO-8876789 CARNMT1 methylates CARN to Anserine IEA Rattus norvegicus 57856 R-RNO-8879123 https://reactome.org/PathwayBrowser/#/R-RNO-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Rattus norvegicus 57856 R-RNO-8931858 https://reactome.org/PathwayBrowser/#/R-RNO-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Rattus norvegicus 57856 R-RNO-8931974 https://reactome.org/PathwayBrowser/#/R-RNO-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Rattus norvegicus 57856 R-RNO-8932221 https://reactome.org/PathwayBrowser/#/R-RNO-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Rattus norvegicus 57856 R-RNO-8932243 https://reactome.org/PathwayBrowser/#/R-RNO-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Rattus norvegicus 57856 R-RNO-8932275 https://reactome.org/PathwayBrowser/#/R-RNO-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Rattus norvegicus 57856 R-RNO-8934735 https://reactome.org/PathwayBrowser/#/R-RNO-8934735 PRMT1 arginine-methylates RUNX1 IEA Rattus norvegicus 57856 R-RNO-8936481 https://reactome.org/PathwayBrowser/#/R-RNO-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Rattus norvegicus 57856 R-RNO-8936584 https://reactome.org/PathwayBrowser/#/R-RNO-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Rattus norvegicus 57856 R-RNO-8936608 https://reactome.org/PathwayBrowser/#/R-RNO-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Rattus norvegicus 57856 R-RNO-8936621 https://reactome.org/PathwayBrowser/#/R-RNO-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Rattus norvegicus 57856 R-RNO-8937016 https://reactome.org/PathwayBrowser/#/R-RNO-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Rattus norvegicus 57856 R-RNO-8937022 https://reactome.org/PathwayBrowser/#/R-RNO-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Rattus norvegicus 57856 R-RNO-8937050 https://reactome.org/PathwayBrowser/#/R-RNO-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Rattus norvegicus 57856 R-RNO-8937113 https://reactome.org/PathwayBrowser/#/R-RNO-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Rattus norvegicus 57856 R-RNO-8955010 https://reactome.org/PathwayBrowser/#/R-RNO-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Rattus norvegicus 57856 R-RNO-9632182 https://reactome.org/PathwayBrowser/#/R-RNO-9632182 PRMT1 methylates ESRs IEA Rattus norvegicus 57856 R-RNO-9647977 https://reactome.org/PathwayBrowser/#/R-RNO-9647977 ICMT methylates S-Farn RAS proteins IEA Rattus norvegicus 57856 R-RNO-9748979 https://reactome.org/PathwayBrowser/#/R-RNO-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Rattus norvegicus 57856 R-RNO-9748983 https://reactome.org/PathwayBrowser/#/R-RNO-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Rattus norvegicus 57856 R-SCE-1483174 https://reactome.org/PathwayBrowser/#/R-SCE-1483174 PE is methylated to PC by PEMT IEA Saccharomyces cerevisiae 57856 R-SCE-174401 https://reactome.org/PathwayBrowser/#/R-SCE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Saccharomyces cerevisiae 57856 R-SCE-2162186 https://reactome.org/PathwayBrowser/#/R-SCE-2162186 COQ3 methylates DeMQ10H2 IEA Saccharomyces cerevisiae 57856 R-SCE-2162188 https://reactome.org/PathwayBrowser/#/R-SCE-2162188 COQ5 methylates MDMQ10H2 IEA Saccharomyces cerevisiae 57856 R-SCE-2162193 https://reactome.org/PathwayBrowser/#/R-SCE-2162193 COQ3 methylates DHDB IEA Saccharomyces cerevisiae 57856 R-SCE-427527 https://reactome.org/PathwayBrowser/#/R-SCE-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Saccharomyces cerevisiae 57856 R-SCE-4827382 https://reactome.org/PathwayBrowser/#/R-SCE-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Saccharomyces cerevisiae 57856 R-SCE-4827383 https://reactome.org/PathwayBrowser/#/R-SCE-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Saccharomyces cerevisiae 57856 R-SCE-5159245 https://reactome.org/PathwayBrowser/#/R-SCE-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Saccharomyces cerevisiae 57856 R-SCE-5205798 https://reactome.org/PathwayBrowser/#/R-SCE-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Saccharomyces cerevisiae 57856 R-SCE-5205867 https://reactome.org/PathwayBrowser/#/R-SCE-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Saccharomyces cerevisiae 57856 R-SCE-5244692 https://reactome.org/PathwayBrowser/#/R-SCE-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Saccharomyces cerevisiae 57856 R-SCE-5358484 https://reactome.org/PathwayBrowser/#/R-SCE-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Saccharomyces cerevisiae 57856 R-SCE-5637686 https://reactome.org/PathwayBrowser/#/R-SCE-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Saccharomyces cerevisiae 57856 R-SCE-5638157 https://reactome.org/PathwayBrowser/#/R-SCE-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Saccharomyces cerevisiae 57856 R-SCE-5638333 https://reactome.org/PathwayBrowser/#/R-SCE-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Saccharomyces cerevisiae 57856 R-SCE-5649764 https://reactome.org/PathwayBrowser/#/R-SCE-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Saccharomyces cerevisiae 57856 R-SCE-5649799 https://reactome.org/PathwayBrowser/#/R-SCE-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Saccharomyces cerevisiae 57856 R-SCE-5649800 https://reactome.org/PathwayBrowser/#/R-SCE-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Saccharomyces cerevisiae 57856 R-SCE-5649801 https://reactome.org/PathwayBrowser/#/R-SCE-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Saccharomyces cerevisiae 57856 R-SCE-5649802 https://reactome.org/PathwayBrowser/#/R-SCE-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Saccharomyces cerevisiae 57856 R-SCE-5661126 https://reactome.org/PathwayBrowser/#/R-SCE-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Saccharomyces cerevisiae 57856 R-SCE-5682965 https://reactome.org/PathwayBrowser/#/R-SCE-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Saccharomyces cerevisiae 57856 R-SCE-6783393 https://reactome.org/PathwayBrowser/#/R-SCE-6783393 PPM2 methoxycarbonylates yW-58 yielding yW at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 57856 R-SCE-6783396 https://reactome.org/PathwayBrowser/#/R-SCE-6783396 TRM5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 57856 R-SCE-6783417 https://reactome.org/PathwayBrowser/#/R-SCE-6783417 PPM2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 57856 R-SCE-6783426 https://reactome.org/PathwayBrowser/#/R-SCE-6783426 TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 57856 R-SCE-6786492 https://reactome.org/PathwayBrowser/#/R-SCE-6786492 TRM11:TRM112 methylates guanosine-10 in tRNA yielding N(2)-methylguanosine-10 TAS Saccharomyces cerevisiae 57856 R-SCE-6786632 https://reactome.org/PathwayBrowser/#/R-SCE-6786632 TRM10 methylates guanosine-9 in tRNA TAS Saccharomyces cerevisiae 57856 R-SCE-6788650 https://reactome.org/PathwayBrowser/#/R-SCE-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Saccharomyces cerevisiae 57856 R-SCE-6788665 https://reactome.org/PathwayBrowser/#/R-SCE-6788665 TRM13 2'-O-methylates adenosine-4 in tRNA TAS Saccharomyces cerevisiae 57856 R-SCE-6788673 https://reactome.org/PathwayBrowser/#/R-SCE-6788673 TRM44 2'-O-methylates uridine-44 in tRNA(Ser) TAS Saccharomyces cerevisiae 57856 R-SCE-6788683 https://reactome.org/PathwayBrowser/#/R-SCE-6788683 TRM13 2'-O-methylates cytidine-4 in tRNA TAS Saccharomyces cerevisiae 57856 R-SCE-6790149 https://reactome.org/PathwayBrowser/#/R-SCE-6790149 NCL1 (TRM4) methylates cytidine-49 of tRNA(Asp) yielding 5-methylcytidine-46 TAS Saccharomyces cerevisiae 57856 R-SCE-6790171 https://reactome.org/PathwayBrowser/#/R-SCE-6790171 TRM9 methylates 5-carboxymethyluridine-34 in tRNA(Arg3) yielding 5-methoxycarbonylmethyluridine-34 TAS Saccharomyces cerevisiae 57856 R-SCE-6790175 https://reactome.org/PathwayBrowser/#/R-SCE-6790175 TRM8:TRM82 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 TAS Saccharomyces cerevisiae 57856 R-SCE-6790189 https://reactome.org/PathwayBrowser/#/R-SCE-6790189 NCL1 (TRM4) methylates cytidine-34 of unspliced tRNA(Leu) yielding 5-methylcytidine-34 TAS Saccharomyces cerevisiae 57856 R-SCE-6790936 https://reactome.org/PathwayBrowser/#/R-SCE-6790936 EMG1 of the SSU processome methylates pseudouridine-1191 of 18S rRNA yielding N(1)-methylpseudouridine-1191 TAS Saccharomyces cerevisiae 57856 R-SCE-6790942 https://reactome.org/PathwayBrowser/#/R-SCE-6790942 NOP2 methylates cytosine-2870 of 25S rRNA yielding 5-methylcytosine-2870 TAS Saccharomyces cerevisiae 57856 R-SCE-6793739 https://reactome.org/PathwayBrowser/#/R-SCE-6793739 Box C/D snoRNP methylates ribonucleotides in pre-rRNA TAS Saccharomyces cerevisiae 57856 R-SCE-6800138 https://reactome.org/PathwayBrowser/#/R-SCE-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Saccharomyces cerevisiae 57856 R-SCE-6800149 https://reactome.org/PathwayBrowser/#/R-SCE-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Saccharomyces cerevisiae 57856 R-SCE-71286 https://reactome.org/PathwayBrowser/#/R-SCE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Saccharomyces cerevisiae 57856 R-SCE-77090 https://reactome.org/PathwayBrowser/#/R-SCE-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Saccharomyces cerevisiae 57856 R-SCE-8855062 https://reactome.org/PathwayBrowser/#/R-SCE-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Saccharomyces cerevisiae 57856 R-SCE-8856945 https://reactome.org/PathwayBrowser/#/R-SCE-8856945 PP2A methylation by LCMT1 IEA Saccharomyces cerevisiae 57856 R-SCE-8876789 https://reactome.org/PathwayBrowser/#/R-SCE-8876789 CARNMT1 methylates CARN to Anserine IEA Saccharomyces cerevisiae 57856 R-SCE-8879123 https://reactome.org/PathwayBrowser/#/R-SCE-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Saccharomyces cerevisiae 57856 R-SCE-8931974 https://reactome.org/PathwayBrowser/#/R-SCE-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Saccharomyces cerevisiae 57856 R-SCE-8932221 https://reactome.org/PathwayBrowser/#/R-SCE-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Saccharomyces cerevisiae 57856 R-SCE-8932243 https://reactome.org/PathwayBrowser/#/R-SCE-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Saccharomyces cerevisiae 57856 R-SCE-8932276 https://reactome.org/PathwayBrowser/#/R-SCE-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Saccharomyces cerevisiae 57856 R-SCE-8932413 https://reactome.org/PathwayBrowser/#/R-SCE-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Saccharomyces cerevisiae 57856 R-SPO-1483174 https://reactome.org/PathwayBrowser/#/R-SPO-1483174 PE is methylated to PC by PEMT IEA Schizosaccharomyces pombe 57856 R-SPO-174401 https://reactome.org/PathwayBrowser/#/R-SPO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Schizosaccharomyces pombe 57856 R-SPO-175983 https://reactome.org/PathwayBrowser/#/R-SPO-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Schizosaccharomyces pombe 57856 R-SPO-2162186 https://reactome.org/PathwayBrowser/#/R-SPO-2162186 COQ3 methylates DeMQ10H2 IEA Schizosaccharomyces pombe 57856 R-SPO-2162188 https://reactome.org/PathwayBrowser/#/R-SPO-2162188 COQ5 methylates MDMQ10H2 IEA Schizosaccharomyces pombe 57856 R-SPO-2162193 https://reactome.org/PathwayBrowser/#/R-SPO-2162193 COQ3 methylates DHDB IEA Schizosaccharomyces pombe 57856 R-SPO-379387 https://reactome.org/PathwayBrowser/#/R-SPO-379387 COMT transfers Met to DA to form 3MT IEA Schizosaccharomyces pombe 57856 R-SPO-427527 https://reactome.org/PathwayBrowser/#/R-SPO-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Schizosaccharomyces pombe 57856 R-SPO-4827382 https://reactome.org/PathwayBrowser/#/R-SPO-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Schizosaccharomyces pombe 57856 R-SPO-4827383 https://reactome.org/PathwayBrowser/#/R-SPO-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Schizosaccharomyces pombe 57856 R-SPO-5159245 https://reactome.org/PathwayBrowser/#/R-SPO-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Schizosaccharomyces pombe 57856 R-SPO-5205798 https://reactome.org/PathwayBrowser/#/R-SPO-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Schizosaccharomyces pombe 57856 R-SPO-5205799 https://reactome.org/PathwayBrowser/#/R-SPO-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Schizosaccharomyces pombe 57856 R-SPO-5205867 https://reactome.org/PathwayBrowser/#/R-SPO-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Schizosaccharomyces pombe 57856 R-SPO-5244692 https://reactome.org/PathwayBrowser/#/R-SPO-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Schizosaccharomyces pombe 57856 R-SPO-5358484 https://reactome.org/PathwayBrowser/#/R-SPO-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Schizosaccharomyces pombe 57856 R-SPO-5634802 https://reactome.org/PathwayBrowser/#/R-SPO-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Schizosaccharomyces pombe 57856 R-SPO-5637686 https://reactome.org/PathwayBrowser/#/R-SPO-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Schizosaccharomyces pombe 57856 R-SPO-5638157 https://reactome.org/PathwayBrowser/#/R-SPO-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Schizosaccharomyces pombe 57856 R-SPO-5638333 https://reactome.org/PathwayBrowser/#/R-SPO-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Schizosaccharomyces pombe 57856 R-SPO-5649800 https://reactome.org/PathwayBrowser/#/R-SPO-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Schizosaccharomyces pombe 57856 R-SPO-5649802 https://reactome.org/PathwayBrowser/#/R-SPO-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Schizosaccharomyces pombe 57856 R-SPO-5651654 https://reactome.org/PathwayBrowser/#/R-SPO-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Schizosaccharomyces pombe 57856 R-SPO-5651657 https://reactome.org/PathwayBrowser/#/R-SPO-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Schizosaccharomyces pombe 57856 R-SPO-5661117 https://reactome.org/PathwayBrowser/#/R-SPO-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Schizosaccharomyces pombe 57856 R-SPO-5661126 https://reactome.org/PathwayBrowser/#/R-SPO-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Schizosaccharomyces pombe 57856 R-SPO-5676966 https://reactome.org/PathwayBrowser/#/R-SPO-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Schizosaccharomyces pombe 57856 R-SPO-5682965 https://reactome.org/PathwayBrowser/#/R-SPO-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Schizosaccharomyces pombe 57856 R-SPO-6788650 https://reactome.org/PathwayBrowser/#/R-SPO-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Schizosaccharomyces pombe 57856 R-SPO-6800138 https://reactome.org/PathwayBrowser/#/R-SPO-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Schizosaccharomyces pombe 57856 R-SPO-6800149 https://reactome.org/PathwayBrowser/#/R-SPO-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Schizosaccharomyces pombe 57856 R-SPO-71286 https://reactome.org/PathwayBrowser/#/R-SPO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Schizosaccharomyces pombe 57856 R-SPO-77090 https://reactome.org/PathwayBrowser/#/R-SPO-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Schizosaccharomyces pombe 57856 R-SPO-8855062 https://reactome.org/PathwayBrowser/#/R-SPO-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Schizosaccharomyces pombe 57856 R-SPO-8856945 https://reactome.org/PathwayBrowser/#/R-SPO-8856945 PP2A methylation by LCMT1 IEA Schizosaccharomyces pombe 57856 R-SPO-8876789 https://reactome.org/PathwayBrowser/#/R-SPO-8876789 CARNMT1 methylates CARN to Anserine IEA Schizosaccharomyces pombe 57856 R-SPO-8879123 https://reactome.org/PathwayBrowser/#/R-SPO-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Schizosaccharomyces pombe 57856 R-SPO-8932221 https://reactome.org/PathwayBrowser/#/R-SPO-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Schizosaccharomyces pombe 57856 R-SPO-8932243 https://reactome.org/PathwayBrowser/#/R-SPO-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Schizosaccharomyces pombe 57856 R-SPO-8932276 https://reactome.org/PathwayBrowser/#/R-SPO-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Schizosaccharomyces pombe 57856 R-SPO-8932413 https://reactome.org/PathwayBrowser/#/R-SPO-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Schizosaccharomyces pombe 57856 R-SPO-8955010 https://reactome.org/PathwayBrowser/#/R-SPO-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Schizosaccharomyces pombe 57856 R-SSC-1483174 https://reactome.org/PathwayBrowser/#/R-SSC-1483174 PE is methylated to PC by PEMT IEA Sus scrofa 57856 R-SSC-158609 https://reactome.org/PathwayBrowser/#/R-SSC-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Sus scrofa 57856 R-SSC-174401 https://reactome.org/PathwayBrowser/#/R-SSC-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Sus scrofa 57856 R-SSC-175983 https://reactome.org/PathwayBrowser/#/R-SSC-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Sus scrofa 57856 R-SSC-175987 https://reactome.org/PathwayBrowser/#/R-SSC-175987 NNMT transfers CH3 from AdoMet to PY IEA Sus scrofa 57856 R-SSC-209821 https://reactome.org/PathwayBrowser/#/R-SSC-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Sus scrofa 57856 R-SSC-209903 https://reactome.org/PathwayBrowser/#/R-SSC-209903 Noradrenaline is converted to adrenaline IEA Sus scrofa 57856 R-SSC-212263 https://reactome.org/PathwayBrowser/#/R-SSC-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Sus scrofa 57856 R-SSC-212269 https://reactome.org/PathwayBrowser/#/R-SSC-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Sus scrofa 57856 R-SSC-2162186 https://reactome.org/PathwayBrowser/#/R-SSC-2162186 COQ3 methylates DeMQ10H2 IEA Sus scrofa 57856 R-SSC-2162188 https://reactome.org/PathwayBrowser/#/R-SSC-2162188 COQ5 methylates MDMQ10H2 IEA Sus scrofa 57856 R-SSC-2162193 https://reactome.org/PathwayBrowser/#/R-SSC-2162193 COQ3 methylates DHDB IEA Sus scrofa 57856 R-SSC-2301205 https://reactome.org/PathwayBrowser/#/R-SSC-2301205 SETD8 monomethylates histone H4 IEA Sus scrofa 57856 R-SSC-3149518 https://reactome.org/PathwayBrowser/#/R-SSC-3149518 MTRR reduces cob(II)alamin to meCbl IEA Sus scrofa 57856 R-SSC-3222237 https://reactome.org/PathwayBrowser/#/R-SSC-3222237 SMYD2 methylates TP53 IEA Sus scrofa 57856 R-SSC-3240295 https://reactome.org/PathwayBrowser/#/R-SSC-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Sus scrofa 57856 R-SSC-3788745 https://reactome.org/PathwayBrowser/#/R-SSC-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Sus scrofa 57856 R-SSC-3788748 https://reactome.org/PathwayBrowser/#/R-SSC-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Sus scrofa 57856 R-SSC-379387 https://reactome.org/PathwayBrowser/#/R-SSC-379387 COMT transfers Met to DA to form 3MT IEA Sus scrofa 57856 R-SSC-427527 https://reactome.org/PathwayBrowser/#/R-SSC-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Sus scrofa 57856 R-SSC-4827382 https://reactome.org/PathwayBrowser/#/R-SSC-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Sus scrofa 57856 R-SSC-4827383 https://reactome.org/PathwayBrowser/#/R-SSC-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Sus scrofa 57856 R-SSC-5159245 https://reactome.org/PathwayBrowser/#/R-SSC-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Sus scrofa 57856 R-SSC-5205798 https://reactome.org/PathwayBrowser/#/R-SSC-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Sus scrofa 57856 R-SSC-5205799 https://reactome.org/PathwayBrowser/#/R-SSC-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Sus scrofa 57856 R-SSC-5205820 https://reactome.org/PathwayBrowser/#/R-SSC-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Sus scrofa 57856 R-SSC-5205822 https://reactome.org/PathwayBrowser/#/R-SSC-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 IEA Sus scrofa 57856 R-SSC-5205824 https://reactome.org/PathwayBrowser/#/R-SSC-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Sus scrofa 57856 R-SSC-5205861 https://reactome.org/PathwayBrowser/#/R-SSC-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Sus scrofa 57856 R-SSC-5205867 https://reactome.org/PathwayBrowser/#/R-SSC-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Sus scrofa 57856 R-SSC-5216234 https://reactome.org/PathwayBrowser/#/R-SSC-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Sus scrofa 57856 R-SSC-5218952 https://reactome.org/PathwayBrowser/#/R-SSC-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Sus scrofa 57856 R-SSC-5229010 https://reactome.org/PathwayBrowser/#/R-SSC-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) IEA Sus scrofa 57856 R-SSC-5229203 https://reactome.org/PathwayBrowser/#/R-SSC-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Sus scrofa 57856 R-SSC-5244692 https://reactome.org/PathwayBrowser/#/R-SSC-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Sus scrofa 57856 R-SSC-5358484 https://reactome.org/PathwayBrowser/#/R-SSC-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Sus scrofa 57856 R-SSC-5359451 https://reactome.org/PathwayBrowser/#/R-SSC-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Sus scrofa 57856 R-SSC-5423038 https://reactome.org/PathwayBrowser/#/R-SSC-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Sus scrofa 57856 R-SSC-5634729 https://reactome.org/PathwayBrowser/#/R-SSC-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Sus scrofa 57856 R-SSC-5634750 https://reactome.org/PathwayBrowser/#/R-SSC-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Sus scrofa 57856 R-SSC-5634802 https://reactome.org/PathwayBrowser/#/R-SSC-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Sus scrofa 57856 R-SSC-5637686 https://reactome.org/PathwayBrowser/#/R-SSC-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Sus scrofa 57856 R-SSC-5638141 https://reactome.org/PathwayBrowser/#/R-SSC-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) IEA Sus scrofa 57856 R-SSC-5638157 https://reactome.org/PathwayBrowser/#/R-SSC-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Sus scrofa 57856 R-SSC-5638332 https://reactome.org/PathwayBrowser/#/R-SSC-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Sus scrofa 57856 R-SSC-5638333 https://reactome.org/PathwayBrowser/#/R-SSC-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Sus scrofa 57856 R-SSC-5649764 https://reactome.org/PathwayBrowser/#/R-SSC-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Sus scrofa 57856 R-SSC-5649799 https://reactome.org/PathwayBrowser/#/R-SSC-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Sus scrofa 57856 R-SSC-5649800 https://reactome.org/PathwayBrowser/#/R-SSC-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Sus scrofa 57856 R-SSC-5649801 https://reactome.org/PathwayBrowser/#/R-SSC-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Sus scrofa 57856 R-SSC-5649802 https://reactome.org/PathwayBrowser/#/R-SSC-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Sus scrofa 57856 R-SSC-5651654 https://reactome.org/PathwayBrowser/#/R-SSC-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Sus scrofa 57856 R-SSC-5651657 https://reactome.org/PathwayBrowser/#/R-SSC-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Sus scrofa 57856 R-SSC-5661117 https://reactome.org/PathwayBrowser/#/R-SSC-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Sus scrofa 57856 R-SSC-5661126 https://reactome.org/PathwayBrowser/#/R-SSC-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Sus scrofa 57856 R-SSC-5676966 https://reactome.org/PathwayBrowser/#/R-SSC-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Sus scrofa 57856 R-SSC-5682965 https://reactome.org/PathwayBrowser/#/R-SSC-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Sus scrofa 57856 R-SSC-5696213 https://reactome.org/PathwayBrowser/#/R-SSC-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Sus scrofa 57856 R-SSC-5696220 https://reactome.org/PathwayBrowser/#/R-SSC-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Sus scrofa 57856 R-SSC-6786205 https://reactome.org/PathwayBrowser/#/R-SSC-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Sus scrofa 57856 R-SSC-6798317 https://reactome.org/PathwayBrowser/#/R-SSC-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Sus scrofa 57856 R-SSC-6800138 https://reactome.org/PathwayBrowser/#/R-SSC-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Sus scrofa 57856 R-SSC-6800149 https://reactome.org/PathwayBrowser/#/R-SSC-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Sus scrofa 57856 R-SSC-6804383 https://reactome.org/PathwayBrowser/#/R-SSC-6804383 PRMT5 methylates TP53 IEA Sus scrofa 57856 R-SSC-6805730 https://reactome.org/PathwayBrowser/#/R-SSC-6805730 SETD9 methylates TP53 IEA Sus scrofa 57856 R-SSC-6805740 https://reactome.org/PathwayBrowser/#/R-SSC-6805740 SETD8 methylates TP53 IEA Sus scrofa 57856 R-SSC-6805755 https://reactome.org/PathwayBrowser/#/R-SSC-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Sus scrofa 57856 R-SSC-71286 https://reactome.org/PathwayBrowser/#/R-SSC-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Sus scrofa 57856 R-SSC-77090 https://reactome.org/PathwayBrowser/#/R-SSC-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Sus scrofa 57856 R-SSC-8855062 https://reactome.org/PathwayBrowser/#/R-SSC-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Sus scrofa 57856 R-SSC-8856945 https://reactome.org/PathwayBrowser/#/R-SSC-8856945 PP2A methylation by LCMT1 IEA Sus scrofa 57856 R-SSC-8865237 https://reactome.org/PathwayBrowser/#/R-SSC-8865237 SETD6 methylates RELA in the NFkB complex IEA Sus scrofa 57856 R-SSC-8876789 https://reactome.org/PathwayBrowser/#/R-SSC-8876789 CARNMT1 methylates CARN to Anserine IEA Sus scrofa 57856 R-SSC-8879123 https://reactome.org/PathwayBrowser/#/R-SSC-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Sus scrofa 57856 R-SSC-8931858 https://reactome.org/PathwayBrowser/#/R-SSC-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Sus scrofa 57856 R-SSC-8931974 https://reactome.org/PathwayBrowser/#/R-SSC-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Sus scrofa 57856 R-SSC-8932221 https://reactome.org/PathwayBrowser/#/R-SSC-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Sus scrofa 57856 R-SSC-8932243 https://reactome.org/PathwayBrowser/#/R-SSC-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Sus scrofa 57856 R-SSC-8932275 https://reactome.org/PathwayBrowser/#/R-SSC-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Sus scrofa 57856 R-SSC-8932276 https://reactome.org/PathwayBrowser/#/R-SSC-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Sus scrofa 57856 R-SSC-8932413 https://reactome.org/PathwayBrowser/#/R-SSC-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Sus scrofa 57856 R-SSC-8934735 https://reactome.org/PathwayBrowser/#/R-SSC-8934735 PRMT1 arginine-methylates RUNX1 IEA Sus scrofa 57856 R-SSC-8936481 https://reactome.org/PathwayBrowser/#/R-SSC-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa 57856 R-SSC-8936584 https://reactome.org/PathwayBrowser/#/R-SSC-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa 57856 R-SSC-8936608 https://reactome.org/PathwayBrowser/#/R-SSC-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa 57856 R-SSC-8936621 https://reactome.org/PathwayBrowser/#/R-SSC-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa 57856 R-SSC-8937016 https://reactome.org/PathwayBrowser/#/R-SSC-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa 57856 R-SSC-8937022 https://reactome.org/PathwayBrowser/#/R-SSC-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa 57856 R-SSC-8937050 https://reactome.org/PathwayBrowser/#/R-SSC-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa 57856 R-SSC-8937113 https://reactome.org/PathwayBrowser/#/R-SSC-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa 57856 R-SSC-8955010 https://reactome.org/PathwayBrowser/#/R-SSC-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Sus scrofa 57856 R-SSC-9632182 https://reactome.org/PathwayBrowser/#/R-SSC-9632182 PRMT1 methylates ESRs IEA Sus scrofa 57856 R-SSC-9748979 https://reactome.org/PathwayBrowser/#/R-SSC-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Sus scrofa 57856 R-SSC-9748983 https://reactome.org/PathwayBrowser/#/R-SSC-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Sus scrofa 57856 R-SSC-9854315 https://reactome.org/PathwayBrowser/#/R-SSC-9854315 CSKMT methylates Citrate Synthase IEA Sus scrofa 57856 R-XTR-1483174 https://reactome.org/PathwayBrowser/#/R-XTR-1483174 PE is methylated to PC by PEMT IEA Xenopus tropicalis 57856 R-XTR-158609 https://reactome.org/PathwayBrowser/#/R-XTR-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Xenopus tropicalis 57856 R-XTR-174401 https://reactome.org/PathwayBrowser/#/R-XTR-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Xenopus tropicalis 57856 R-XTR-175983 https://reactome.org/PathwayBrowser/#/R-XTR-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Xenopus tropicalis 57856 R-XTR-175987 https://reactome.org/PathwayBrowser/#/R-XTR-175987 NNMT transfers CH3 from AdoMet to PY IEA Xenopus tropicalis 57856 R-XTR-209821 https://reactome.org/PathwayBrowser/#/R-XTR-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Xenopus tropicalis 57856 R-XTR-212263 https://reactome.org/PathwayBrowser/#/R-XTR-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Xenopus tropicalis 57856 R-XTR-212269 https://reactome.org/PathwayBrowser/#/R-XTR-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Xenopus tropicalis 57856 R-XTR-2162186 https://reactome.org/PathwayBrowser/#/R-XTR-2162186 COQ3 methylates DeMQ10H2 IEA Xenopus tropicalis 57856 R-XTR-2162188 https://reactome.org/PathwayBrowser/#/R-XTR-2162188 COQ5 methylates MDMQ10H2 IEA Xenopus tropicalis 57856 R-XTR-2162193 https://reactome.org/PathwayBrowser/#/R-XTR-2162193 COQ3 methylates DHDB IEA Xenopus tropicalis 57856 R-XTR-2301205 https://reactome.org/PathwayBrowser/#/R-XTR-2301205 SETD8 monomethylates histone H4 IEA Xenopus tropicalis 57856 R-XTR-3240295 https://reactome.org/PathwayBrowser/#/R-XTR-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Xenopus tropicalis 57856 R-XTR-3788745 https://reactome.org/PathwayBrowser/#/R-XTR-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Xenopus tropicalis 57856 R-XTR-3788748 https://reactome.org/PathwayBrowser/#/R-XTR-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Xenopus tropicalis 57856 R-XTR-379387 https://reactome.org/PathwayBrowser/#/R-XTR-379387 COMT transfers Met to DA to form 3MT IEA Xenopus tropicalis 57856 R-XTR-5205820 https://reactome.org/PathwayBrowser/#/R-XTR-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Xenopus tropicalis 57856 R-XTR-5205867 https://reactome.org/PathwayBrowser/#/R-XTR-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Xenopus tropicalis 57856 R-XTR-5216234 https://reactome.org/PathwayBrowser/#/R-XTR-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Xenopus tropicalis 57856 R-XTR-5229203 https://reactome.org/PathwayBrowser/#/R-XTR-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Xenopus tropicalis 57856 R-XTR-5358484 https://reactome.org/PathwayBrowser/#/R-XTR-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Xenopus tropicalis 57856 R-XTR-5359451 https://reactome.org/PathwayBrowser/#/R-XTR-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Xenopus tropicalis 57856 R-XTR-5696213 https://reactome.org/PathwayBrowser/#/R-XTR-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Xenopus tropicalis 57856 R-XTR-5696220 https://reactome.org/PathwayBrowser/#/R-XTR-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Xenopus tropicalis 57856 R-XTR-6788650 https://reactome.org/PathwayBrowser/#/R-XTR-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Xenopus tropicalis 57856 R-XTR-6798317 https://reactome.org/PathwayBrowser/#/R-XTR-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Xenopus tropicalis 57856 R-XTR-6800149 https://reactome.org/PathwayBrowser/#/R-XTR-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Xenopus tropicalis 57856 R-XTR-6804383 https://reactome.org/PathwayBrowser/#/R-XTR-6804383 PRMT5 methylates TP53 IEA Xenopus tropicalis 57856 R-XTR-6805740 https://reactome.org/PathwayBrowser/#/R-XTR-6805740 SETD8 methylates TP53 IEA Xenopus tropicalis 57856 R-XTR-6805755 https://reactome.org/PathwayBrowser/#/R-XTR-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Xenopus tropicalis 57856 R-XTR-71286 https://reactome.org/PathwayBrowser/#/R-XTR-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Xenopus tropicalis 57856 R-XTR-8855062 https://reactome.org/PathwayBrowser/#/R-XTR-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Xenopus tropicalis 57856 R-XTR-8856945 https://reactome.org/PathwayBrowser/#/R-XTR-8856945 PP2A methylation by LCMT1 IEA Xenopus tropicalis 57856 R-XTR-8879123 https://reactome.org/PathwayBrowser/#/R-XTR-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Xenopus tropicalis 57856 R-XTR-8931858 https://reactome.org/PathwayBrowser/#/R-XTR-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Xenopus tropicalis 57856 R-XTR-8931974 https://reactome.org/PathwayBrowser/#/R-XTR-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Xenopus tropicalis 57856 R-XTR-8932221 https://reactome.org/PathwayBrowser/#/R-XTR-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Xenopus tropicalis 57856 R-XTR-8932243 https://reactome.org/PathwayBrowser/#/R-XTR-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Xenopus tropicalis 57856 R-XTR-8932275 https://reactome.org/PathwayBrowser/#/R-XTR-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Xenopus tropicalis 57856 R-XTR-8932276 https://reactome.org/PathwayBrowser/#/R-XTR-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Xenopus tropicalis 57856 R-XTR-8936481 https://reactome.org/PathwayBrowser/#/R-XTR-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Xenopus tropicalis 57856 R-XTR-8936584 https://reactome.org/PathwayBrowser/#/R-XTR-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Xenopus tropicalis 57856 R-XTR-8936608 https://reactome.org/PathwayBrowser/#/R-XTR-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Xenopus tropicalis 57856 R-XTR-8936621 https://reactome.org/PathwayBrowser/#/R-XTR-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Xenopus tropicalis 57856 R-XTR-8937016 https://reactome.org/PathwayBrowser/#/R-XTR-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Xenopus tropicalis 57856 R-XTR-8937022 https://reactome.org/PathwayBrowser/#/R-XTR-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Xenopus tropicalis 57856 R-XTR-8937050 https://reactome.org/PathwayBrowser/#/R-XTR-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Xenopus tropicalis 57856 R-XTR-8937113 https://reactome.org/PathwayBrowser/#/R-XTR-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Xenopus tropicalis 57856 R-XTR-9632182 https://reactome.org/PathwayBrowser/#/R-XTR-9632182 PRMT1 methylates ESRs IEA Xenopus tropicalis 57856 R-XTR-9748979 https://reactome.org/PathwayBrowser/#/R-XTR-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Xenopus tropicalis 57856 R-XTR-9748983 https://reactome.org/PathwayBrowser/#/R-XTR-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Xenopus tropicalis 57865 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 57865 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 57865 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 57865 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 57865 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 57865 R-BTA-109903 https://reactome.org/PathwayBrowser/#/R-BTA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Bos taurus 57865 R-BTA-174441 https://reactome.org/PathwayBrowser/#/R-BTA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Bos taurus 57865 R-BTA-3780994 https://reactome.org/PathwayBrowser/#/R-BTA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Bos taurus 57865 R-BTA-3781024 https://reactome.org/PathwayBrowser/#/R-BTA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Bos taurus 57865 R-BTA-430028 https://reactome.org/PathwayBrowser/#/R-BTA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Bos taurus 57865 R-BTA-446191 https://reactome.org/PathwayBrowser/#/R-BTA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Bos taurus 57865 R-BTA-6810464 https://reactome.org/PathwayBrowser/#/R-BTA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Bos taurus 57865 R-BTA-69144 https://reactome.org/PathwayBrowser/#/R-BTA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Bos taurus 57865 R-BTA-73548 https://reactome.org/PathwayBrowser/#/R-BTA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Bos taurus 57865 R-BTA-73564 https://reactome.org/PathwayBrowser/#/R-BTA-73564 UMPS dimer decarboxylates OMP to UMP IEA Bos taurus 57865 R-BTA-735702 https://reactome.org/PathwayBrowser/#/R-BTA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Bos taurus 57865 R-BTA-73599 https://reactome.org/PathwayBrowser/#/R-BTA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Bos taurus 57865 R-BTA-741450 https://reactome.org/PathwayBrowser/#/R-BTA-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Bos taurus 57865 R-BTA-744231 https://reactome.org/PathwayBrowser/#/R-BTA-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Bos taurus 57865 R-BTA-75125 https://reactome.org/PathwayBrowser/#/R-BTA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Bos taurus 57865 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 57865 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 57865 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 57865 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 57865 R-BTA-8954327 https://reactome.org/PathwayBrowser/#/R-BTA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Bos taurus 57865 R-BTA-9792608 https://reactome.org/PathwayBrowser/#/R-BTA-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Bos taurus 57865 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 57865 R-CEL-109903 https://reactome.org/PathwayBrowser/#/R-CEL-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Caenorhabditis elegans 57865 R-CEL-3780994 https://reactome.org/PathwayBrowser/#/R-CEL-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Caenorhabditis elegans 57865 R-CEL-3781024 https://reactome.org/PathwayBrowser/#/R-CEL-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Caenorhabditis elegans 57865 R-CEL-430028 https://reactome.org/PathwayBrowser/#/R-CEL-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Caenorhabditis elegans 57865 R-CEL-446191 https://reactome.org/PathwayBrowser/#/R-CEL-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Caenorhabditis elegans 57865 R-CEL-6810464 https://reactome.org/PathwayBrowser/#/R-CEL-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Caenorhabditis elegans 57865 R-CEL-73548 https://reactome.org/PathwayBrowser/#/R-CEL-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Caenorhabditis elegans 57865 R-CEL-73564 https://reactome.org/PathwayBrowser/#/R-CEL-73564 UMPS dimer decarboxylates OMP to UMP IEA Caenorhabditis elegans 57865 R-CEL-735702 https://reactome.org/PathwayBrowser/#/R-CEL-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Caenorhabditis elegans 57865 R-CEL-73599 https://reactome.org/PathwayBrowser/#/R-CEL-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Caenorhabditis elegans 57865 R-CEL-741450 https://reactome.org/PathwayBrowser/#/R-CEL-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Caenorhabditis elegans 57865 R-CEL-744231 https://reactome.org/PathwayBrowser/#/R-CEL-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Caenorhabditis elegans 57865 R-CEL-75125 https://reactome.org/PathwayBrowser/#/R-CEL-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Caenorhabditis elegans 57865 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 57865 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 57865 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 57865 R-CEL-8954327 https://reactome.org/PathwayBrowser/#/R-CEL-8954327 UCKL1 phosphorylates urindine, cytidine IEA Caenorhabditis elegans 57865 R-CEL-9792608 https://reactome.org/PathwayBrowser/#/R-CEL-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Caenorhabditis elegans 57865 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 57865 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 57865 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 57865 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 57865 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 57865 R-CFA-109903 https://reactome.org/PathwayBrowser/#/R-CFA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Canis familiaris 57865 R-CFA-174441 https://reactome.org/PathwayBrowser/#/R-CFA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Canis familiaris 57865 R-CFA-3780994 https://reactome.org/PathwayBrowser/#/R-CFA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Canis familiaris 57865 R-CFA-3781024 https://reactome.org/PathwayBrowser/#/R-CFA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Canis familiaris 57865 R-CFA-430028 https://reactome.org/PathwayBrowser/#/R-CFA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Canis familiaris 57865 R-CFA-446191 https://reactome.org/PathwayBrowser/#/R-CFA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Canis familiaris 57865 R-CFA-69144 https://reactome.org/PathwayBrowser/#/R-CFA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Canis familiaris 57865 R-CFA-73548 https://reactome.org/PathwayBrowser/#/R-CFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Canis familiaris 57865 R-CFA-73564 https://reactome.org/PathwayBrowser/#/R-CFA-73564 UMPS dimer decarboxylates OMP to UMP IEA Canis familiaris 57865 R-CFA-735702 https://reactome.org/PathwayBrowser/#/R-CFA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Canis familiaris 57865 R-CFA-73599 https://reactome.org/PathwayBrowser/#/R-CFA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Canis familiaris 57865 R-CFA-741450 https://reactome.org/PathwayBrowser/#/R-CFA-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Canis familiaris 57865 R-CFA-744231 https://reactome.org/PathwayBrowser/#/R-CFA-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Canis familiaris 57865 R-CFA-75125 https://reactome.org/PathwayBrowser/#/R-CFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Canis familiaris 57865 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 57865 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 57865 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 57865 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 57865 R-CFA-8954327 https://reactome.org/PathwayBrowser/#/R-CFA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Canis familiaris 57865 R-CFA-9792608 https://reactome.org/PathwayBrowser/#/R-CFA-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Canis familiaris 57865 R-DDI-109903 https://reactome.org/PathwayBrowser/#/R-DDI-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Dictyostelium discoideum 57865 R-DDI-430028 https://reactome.org/PathwayBrowser/#/R-DDI-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Dictyostelium discoideum 57865 R-DDI-446191 https://reactome.org/PathwayBrowser/#/R-DDI-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Dictyostelium discoideum 57865 R-DDI-73548 https://reactome.org/PathwayBrowser/#/R-DDI-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Dictyostelium discoideum 57865 R-DDI-73564 https://reactome.org/PathwayBrowser/#/R-DDI-73564 UMPS dimer decarboxylates OMP to UMP IEA Dictyostelium discoideum 57865 R-DDI-73599 https://reactome.org/PathwayBrowser/#/R-DDI-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Dictyostelium discoideum 57865 R-DDI-744231 https://reactome.org/PathwayBrowser/#/R-DDI-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Dictyostelium discoideum 57865 R-DDI-75125 https://reactome.org/PathwayBrowser/#/R-DDI-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Dictyostelium discoideum 57865 R-DDI-8954327 https://reactome.org/PathwayBrowser/#/R-DDI-8954327 UCKL1 phosphorylates urindine, cytidine IEA Dictyostelium discoideum 57865 R-DDI-9792608 https://reactome.org/PathwayBrowser/#/R-DDI-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Dictyostelium discoideum 57865 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 57865 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 57865 R-DME-109903 https://reactome.org/PathwayBrowser/#/R-DME-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Drosophila melanogaster 57865 R-DME-3780994 https://reactome.org/PathwayBrowser/#/R-DME-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Drosophila melanogaster 57865 R-DME-3781024 https://reactome.org/PathwayBrowser/#/R-DME-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Drosophila melanogaster 57865 R-DME-430028 https://reactome.org/PathwayBrowser/#/R-DME-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Drosophila melanogaster 57865 R-DME-446191 https://reactome.org/PathwayBrowser/#/R-DME-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Drosophila melanogaster 57865 R-DME-6810464 https://reactome.org/PathwayBrowser/#/R-DME-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Drosophila melanogaster 57865 R-DME-69144 https://reactome.org/PathwayBrowser/#/R-DME-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Drosophila melanogaster 57865 R-DME-73548 https://reactome.org/PathwayBrowser/#/R-DME-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Drosophila melanogaster 57865 R-DME-73564 https://reactome.org/PathwayBrowser/#/R-DME-73564 UMPS dimer decarboxylates OMP to UMP IEA Drosophila melanogaster 57865 R-DME-735702 https://reactome.org/PathwayBrowser/#/R-DME-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Drosophila melanogaster 57865 R-DME-73599 https://reactome.org/PathwayBrowser/#/R-DME-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Drosophila melanogaster 57865 R-DME-744231 https://reactome.org/PathwayBrowser/#/R-DME-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Drosophila melanogaster 57865 R-DME-75125 https://reactome.org/PathwayBrowser/#/R-DME-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Drosophila melanogaster 57865 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 57865 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 57865 R-DME-8954327 https://reactome.org/PathwayBrowser/#/R-DME-8954327 UCKL1 phosphorylates urindine, cytidine IEA Drosophila melanogaster 57865 R-DME-9792608 https://reactome.org/PathwayBrowser/#/R-DME-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Drosophila melanogaster 57865 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 57865 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 57865 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 57865 R-DRE-109903 https://reactome.org/PathwayBrowser/#/R-DRE-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Danio rerio 57865 R-DRE-3781024 https://reactome.org/PathwayBrowser/#/R-DRE-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Danio rerio 57865 R-DRE-446191 https://reactome.org/PathwayBrowser/#/R-DRE-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Danio rerio 57865 R-DRE-6810464 https://reactome.org/PathwayBrowser/#/R-DRE-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Danio rerio 57865 R-DRE-73548 https://reactome.org/PathwayBrowser/#/R-DRE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Danio rerio 57865 R-DRE-73599 https://reactome.org/PathwayBrowser/#/R-DRE-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Danio rerio 57865 R-DRE-741450 https://reactome.org/PathwayBrowser/#/R-DRE-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Danio rerio 57865 R-DRE-75125 https://reactome.org/PathwayBrowser/#/R-DRE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Danio rerio 57865 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 57865 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 57865 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 57865 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 57865 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 57865 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 57865 R-GGA-109903 https://reactome.org/PathwayBrowser/#/R-GGA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Gallus gallus 57865 R-GGA-3780994 https://reactome.org/PathwayBrowser/#/R-GGA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Gallus gallus 57865 R-GGA-3781024 https://reactome.org/PathwayBrowser/#/R-GGA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Gallus gallus 57865 R-GGA-419461 https://reactome.org/PathwayBrowser/#/R-GGA-419461 orotidine 5'-monophosphate => uridine 5'-monophosphate + CO2 IEA Gallus gallus 57865 R-GGA-430028 https://reactome.org/PathwayBrowser/#/R-GGA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Gallus gallus 57865 R-GGA-446191 https://reactome.org/PathwayBrowser/#/R-GGA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Gallus gallus 57865 R-GGA-6810464 https://reactome.org/PathwayBrowser/#/R-GGA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Gallus gallus 57865 R-GGA-73548 https://reactome.org/PathwayBrowser/#/R-GGA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Gallus gallus 57865 R-GGA-73564 https://reactome.org/PathwayBrowser/#/R-GGA-73564 UMPS dimer decarboxylates OMP to UMP IEA Gallus gallus 57865 R-GGA-73599 https://reactome.org/PathwayBrowser/#/R-GGA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Gallus gallus 57865 R-GGA-741450 https://reactome.org/PathwayBrowser/#/R-GGA-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Gallus gallus 57865 R-GGA-744231 https://reactome.org/PathwayBrowser/#/R-GGA-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Gallus gallus 57865 R-GGA-75125 https://reactome.org/PathwayBrowser/#/R-GGA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Gallus gallus 57865 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 57865 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 57865 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 57865 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 57865 R-GGA-8954327 https://reactome.org/PathwayBrowser/#/R-GGA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Gallus gallus 57865 R-GGA-9792608 https://reactome.org/PathwayBrowser/#/R-GGA-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Gallus gallus 57865 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 57865 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 57865 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 57865 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 57865 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 57865 R-HSA-109903 https://reactome.org/PathwayBrowser/#/R-HSA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] TAS Homo sapiens 57865 R-HSA-174441 https://reactome.org/PathwayBrowser/#/R-HSA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand TAS Homo sapiens 57865 R-HSA-3780994 https://reactome.org/PathwayBrowser/#/R-HSA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 TAS Homo sapiens 57865 R-HSA-3781024 https://reactome.org/PathwayBrowser/#/R-HSA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 TAS Homo sapiens 57865 R-HSA-429845 https://reactome.org/PathwayBrowser/#/R-HSA-429845 5' to 3' exoribonuclease hydrolyzes decapped mRNA IEA Homo sapiens 57865 R-HSA-430028 https://reactome.org/PathwayBrowser/#/R-HSA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion TAS Homo sapiens 57865 R-HSA-446191 https://reactome.org/PathwayBrowser/#/R-HSA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate TAS Homo sapiens 57865 R-HSA-5652099 https://reactome.org/PathwayBrowser/#/R-HSA-5652099 Defective SLC35A2 does not exchange UDP-Gal, UDP-GalNAc for UMP TAS Homo sapiens 57865 R-HSA-5653622 https://reactome.org/PathwayBrowser/#/R-HSA-5653622 Defective SLC35A3 does not exchange UDP-GlcNAc for UMP TAS Homo sapiens 57865 R-HSA-6810464 https://reactome.org/PathwayBrowser/#/R-HSA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP TAS Homo sapiens 57865 R-HSA-69144 https://reactome.org/PathwayBrowser/#/R-HSA-69144 Removal of RNA primer and dissociation of RPA and Dna2 TAS Homo sapiens 57865 R-HSA-73548 https://reactome.org/PathwayBrowser/#/R-HSA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) TAS Homo sapiens 57865 R-HSA-73564 https://reactome.org/PathwayBrowser/#/R-HSA-73564 UMPS dimer decarboxylates OMP to UMP TAS Homo sapiens 57865 R-HSA-735702 https://reactome.org/PathwayBrowser/#/R-HSA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP TAS Homo sapiens 57865 R-HSA-73599 https://reactome.org/PathwayBrowser/#/R-HSA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] TAS Homo sapiens 57865 R-HSA-741450 https://reactome.org/PathwayBrowser/#/R-HSA-741450 SLC35A3 exchanges UDP-GlcNAc for UMP TAS Homo sapiens 57865 R-HSA-744231 https://reactome.org/PathwayBrowser/#/R-HSA-744231 SLC35D2 exchanges UDP-GlcNAc for UMP TAS Homo sapiens 57865 R-HSA-75125 https://reactome.org/PathwayBrowser/#/R-HSA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) TAS Homo sapiens 57865 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 57865 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 57865 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 57865 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 57865 R-HSA-8954327 https://reactome.org/PathwayBrowser/#/R-HSA-8954327 UCKL1 phosphorylates urindine, cytidine TAS Homo sapiens 57865 R-HSA-9792608 https://reactome.org/PathwayBrowser/#/R-HSA-9792608 SLC35D2 exchanges UDP-D-glucose for UMP TAS Homo sapiens 57865 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 57865 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 57865 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 57865 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 57865 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 57865 R-MMU-109903 https://reactome.org/PathwayBrowser/#/R-MMU-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Mus musculus 57865 R-MMU-174441 https://reactome.org/PathwayBrowser/#/R-MMU-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Mus musculus 57865 R-MMU-3781024 https://reactome.org/PathwayBrowser/#/R-MMU-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Mus musculus 57865 R-MMU-430028 https://reactome.org/PathwayBrowser/#/R-MMU-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Mus musculus 57865 R-MMU-446191 https://reactome.org/PathwayBrowser/#/R-MMU-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Mus musculus 57865 R-MMU-6810464 https://reactome.org/PathwayBrowser/#/R-MMU-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Mus musculus 57865 R-MMU-69144 https://reactome.org/PathwayBrowser/#/R-MMU-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Mus musculus 57865 R-MMU-73548 https://reactome.org/PathwayBrowser/#/R-MMU-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Mus musculus 57865 R-MMU-73564 https://reactome.org/PathwayBrowser/#/R-MMU-73564 UMPS dimer decarboxylates OMP to UMP IEA Mus musculus 57865 R-MMU-735702 https://reactome.org/PathwayBrowser/#/R-MMU-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Mus musculus 57865 R-MMU-73599 https://reactome.org/PathwayBrowser/#/R-MMU-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Mus musculus 57865 R-MMU-741450 https://reactome.org/PathwayBrowser/#/R-MMU-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Mus musculus 57865 R-MMU-744231 https://reactome.org/PathwayBrowser/#/R-MMU-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Mus musculus 57865 R-MMU-75125 https://reactome.org/PathwayBrowser/#/R-MMU-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Mus musculus 57865 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 57865 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 57865 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 57865 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 57865 R-MMU-8954327 https://reactome.org/PathwayBrowser/#/R-MMU-8954327 UCKL1 phosphorylates urindine, cytidine IEA Mus musculus 57865 R-MMU-9792608 https://reactome.org/PathwayBrowser/#/R-MMU-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Mus musculus 57865 R-PFA-446191 https://reactome.org/PathwayBrowser/#/R-PFA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Plasmodium falciparum 57865 R-PFA-73548 https://reactome.org/PathwayBrowser/#/R-PFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Plasmodium falciparum 57865 R-PFA-735702 https://reactome.org/PathwayBrowser/#/R-PFA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Plasmodium falciparum 57865 R-PFA-75125 https://reactome.org/PathwayBrowser/#/R-PFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Plasmodium falciparum 57865 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 57865 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 57865 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 57865 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 57865 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 57865 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 57865 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 57865 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 57865 R-RNO-109903 https://reactome.org/PathwayBrowser/#/R-RNO-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Rattus norvegicus 57865 R-RNO-174441 https://reactome.org/PathwayBrowser/#/R-RNO-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Rattus norvegicus 57865 R-RNO-3781024 https://reactome.org/PathwayBrowser/#/R-RNO-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Rattus norvegicus 57865 R-RNO-430028 https://reactome.org/PathwayBrowser/#/R-RNO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Rattus norvegicus 57865 R-RNO-446191 https://reactome.org/PathwayBrowser/#/R-RNO-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Rattus norvegicus 57865 R-RNO-6810464 https://reactome.org/PathwayBrowser/#/R-RNO-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Rattus norvegicus 57865 R-RNO-69144 https://reactome.org/PathwayBrowser/#/R-RNO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Rattus norvegicus 57865 R-RNO-73548 https://reactome.org/PathwayBrowser/#/R-RNO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Rattus norvegicus 57865 R-RNO-73564 https://reactome.org/PathwayBrowser/#/R-RNO-73564 UMPS dimer decarboxylates OMP to UMP IEA Rattus norvegicus 57865 R-RNO-735702 https://reactome.org/PathwayBrowser/#/R-RNO-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Rattus norvegicus 57865 R-RNO-73599 https://reactome.org/PathwayBrowser/#/R-RNO-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Rattus norvegicus 57865 R-RNO-741450 https://reactome.org/PathwayBrowser/#/R-RNO-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Rattus norvegicus 57865 R-RNO-744231 https://reactome.org/PathwayBrowser/#/R-RNO-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Rattus norvegicus 57865 R-RNO-75125 https://reactome.org/PathwayBrowser/#/R-RNO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Rattus norvegicus 57865 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 57865 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 57865 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 57865 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 57865 R-RNO-8954327 https://reactome.org/PathwayBrowser/#/R-RNO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Rattus norvegicus 57865 R-RNO-9792608 https://reactome.org/PathwayBrowser/#/R-RNO-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Rattus norvegicus 57865 R-SCE-3780994 https://reactome.org/PathwayBrowser/#/R-SCE-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Saccharomyces cerevisiae 57865 R-SCE-3781024 https://reactome.org/PathwayBrowser/#/R-SCE-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Saccharomyces cerevisiae 57865 R-SCE-429913 https://reactome.org/PathwayBrowser/#/R-SCE-429913 5' to 3' Exoribonuclease Digestion of Decapped mRNA (yeast) TAS Saccharomyces cerevisiae 57865 R-SCE-430028 https://reactome.org/PathwayBrowser/#/R-SCE-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Saccharomyces cerevisiae 57865 R-SCE-446191 https://reactome.org/PathwayBrowser/#/R-SCE-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Saccharomyces cerevisiae 57865 R-SCE-73548 https://reactome.org/PathwayBrowser/#/R-SCE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Saccharomyces cerevisiae 57865 R-SCE-75125 https://reactome.org/PathwayBrowser/#/R-SCE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Saccharomyces cerevisiae 57865 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 57865 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 57865 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 57865 R-SCE-8954327 https://reactome.org/PathwayBrowser/#/R-SCE-8954327 UCKL1 phosphorylates urindine, cytidine IEA Saccharomyces cerevisiae 57865 R-SPO-430028 https://reactome.org/PathwayBrowser/#/R-SPO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Schizosaccharomyces pombe 57865 R-SPO-446191 https://reactome.org/PathwayBrowser/#/R-SPO-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Schizosaccharomyces pombe 57865 R-SPO-69144 https://reactome.org/PathwayBrowser/#/R-SPO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Schizosaccharomyces pombe 57865 R-SPO-73548 https://reactome.org/PathwayBrowser/#/R-SPO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Schizosaccharomyces pombe 57865 R-SPO-741450 https://reactome.org/PathwayBrowser/#/R-SPO-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Schizosaccharomyces pombe 57865 R-SPO-75125 https://reactome.org/PathwayBrowser/#/R-SPO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Schizosaccharomyces pombe 57865 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 57865 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 57865 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 57865 R-SPO-8954327 https://reactome.org/PathwayBrowser/#/R-SPO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Schizosaccharomyces pombe 57865 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 57865 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 57865 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 57865 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 57865 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 57865 R-SSC-109903 https://reactome.org/PathwayBrowser/#/R-SSC-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Sus scrofa 57865 R-SSC-174441 https://reactome.org/PathwayBrowser/#/R-SSC-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Sus scrofa 57865 R-SSC-3780994 https://reactome.org/PathwayBrowser/#/R-SSC-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Sus scrofa 57865 R-SSC-3781024 https://reactome.org/PathwayBrowser/#/R-SSC-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Sus scrofa 57865 R-SSC-430028 https://reactome.org/PathwayBrowser/#/R-SSC-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Sus scrofa 57865 R-SSC-446191 https://reactome.org/PathwayBrowser/#/R-SSC-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Sus scrofa 57865 R-SSC-6810464 https://reactome.org/PathwayBrowser/#/R-SSC-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Sus scrofa 57865 R-SSC-69144 https://reactome.org/PathwayBrowser/#/R-SSC-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Sus scrofa 57865 R-SSC-73548 https://reactome.org/PathwayBrowser/#/R-SSC-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Sus scrofa 57865 R-SSC-73564 https://reactome.org/PathwayBrowser/#/R-SSC-73564 UMPS dimer decarboxylates OMP to UMP IEA Sus scrofa 57865 R-SSC-735702 https://reactome.org/PathwayBrowser/#/R-SSC-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Sus scrofa 57865 R-SSC-73599 https://reactome.org/PathwayBrowser/#/R-SSC-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Sus scrofa 57865 R-SSC-741450 https://reactome.org/PathwayBrowser/#/R-SSC-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Sus scrofa 57865 R-SSC-744231 https://reactome.org/PathwayBrowser/#/R-SSC-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Sus scrofa 57865 R-SSC-75125 https://reactome.org/PathwayBrowser/#/R-SSC-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Sus scrofa 57865 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 57865 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 57865 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 57865 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 57865 R-SSC-8954327 https://reactome.org/PathwayBrowser/#/R-SSC-8954327 UCKL1 phosphorylates urindine, cytidine IEA Sus scrofa 57865 R-SSC-9792608 https://reactome.org/PathwayBrowser/#/R-SSC-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Sus scrofa 57865 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 57865 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 57865 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 57865 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 57865 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 57865 R-XTR-109903 https://reactome.org/PathwayBrowser/#/R-XTR-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Xenopus tropicalis 57865 R-XTR-430028 https://reactome.org/PathwayBrowser/#/R-XTR-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Xenopus tropicalis 57865 R-XTR-446191 https://reactome.org/PathwayBrowser/#/R-XTR-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Xenopus tropicalis 57865 R-XTR-73564 https://reactome.org/PathwayBrowser/#/R-XTR-73564 UMPS dimer decarboxylates OMP to UMP IEA Xenopus tropicalis 57865 R-XTR-73599 https://reactome.org/PathwayBrowser/#/R-XTR-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Xenopus tropicalis 57865 R-XTR-741450 https://reactome.org/PathwayBrowser/#/R-XTR-741450 SLC35A3 exchanges UDP-GlcNAc for UMP IEA Xenopus tropicalis 57865 R-XTR-744231 https://reactome.org/PathwayBrowser/#/R-XTR-744231 SLC35D2 exchanges UDP-GlcNAc for UMP IEA Xenopus tropicalis 57865 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 57865 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 57865 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 57865 R-XTR-8954327 https://reactome.org/PathwayBrowser/#/R-XTR-8954327 UCKL1 phosphorylates urindine, cytidine IEA Xenopus tropicalis 57865 R-XTR-9792608 https://reactome.org/PathwayBrowser/#/R-XTR-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Xenopus tropicalis 57876 R-BTA-1482962 https://reactome.org/PathwayBrowser/#/R-BTA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Bos taurus 57876 R-BTA-1483190 https://reactome.org/PathwayBrowser/#/R-BTA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Bos taurus 57876 R-CEL-1482962 https://reactome.org/PathwayBrowser/#/R-CEL-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Caenorhabditis elegans 57876 R-CEL-1483190 https://reactome.org/PathwayBrowser/#/R-CEL-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Caenorhabditis elegans 57876 R-CFA-1482962 https://reactome.org/PathwayBrowser/#/R-CFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Canis familiaris 57876 R-CFA-1483190 https://reactome.org/PathwayBrowser/#/R-CFA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Canis familiaris 57876 R-DDI-1482962 https://reactome.org/PathwayBrowser/#/R-DDI-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Dictyostelium discoideum 57876 R-DDI-1483190 https://reactome.org/PathwayBrowser/#/R-DDI-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Dictyostelium discoideum 57876 R-DME-1482962 https://reactome.org/PathwayBrowser/#/R-DME-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Drosophila melanogaster 57876 R-DME-1483190 https://reactome.org/PathwayBrowser/#/R-DME-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Drosophila melanogaster 57876 R-DRE-1482962 https://reactome.org/PathwayBrowser/#/R-DRE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Danio rerio 57876 R-DRE-1483190 https://reactome.org/PathwayBrowser/#/R-DRE-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Danio rerio 57876 R-GGA-1482962 https://reactome.org/PathwayBrowser/#/R-GGA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Gallus gallus 57876 R-GGA-1483190 https://reactome.org/PathwayBrowser/#/R-GGA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Gallus gallus 57876 R-HSA-1482962 https://reactome.org/PathwayBrowser/#/R-HSA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 TAS Homo sapiens 57876 R-HSA-1483190 https://reactome.org/PathwayBrowser/#/R-HSA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 TAS Homo sapiens 57876 R-MMU-1482962 https://reactome.org/PathwayBrowser/#/R-MMU-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Mus musculus 57876 R-MMU-1483190 https://reactome.org/PathwayBrowser/#/R-MMU-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Mus musculus 57876 R-PFA-1482962 https://reactome.org/PathwayBrowser/#/R-PFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Plasmodium falciparum 57876 R-PFA-1483190 https://reactome.org/PathwayBrowser/#/R-PFA-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Plasmodium falciparum 57876 R-RNO-1482962 https://reactome.org/PathwayBrowser/#/R-RNO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Rattus norvegicus 57876 R-RNO-1483190 https://reactome.org/PathwayBrowser/#/R-RNO-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Rattus norvegicus 57876 R-SCE-1482962 https://reactome.org/PathwayBrowser/#/R-SCE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Saccharomyces cerevisiae 57876 R-SCE-1483190 https://reactome.org/PathwayBrowser/#/R-SCE-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Saccharomyces cerevisiae 57876 R-SPO-1482962 https://reactome.org/PathwayBrowser/#/R-SPO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Schizosaccharomyces pombe 57876 R-SPO-1483190 https://reactome.org/PathwayBrowser/#/R-SPO-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Schizosaccharomyces pombe 57876 R-SSC-1482962 https://reactome.org/PathwayBrowser/#/R-SSC-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Sus scrofa 57876 R-SSC-1483190 https://reactome.org/PathwayBrowser/#/R-SSC-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Sus scrofa 57876 R-XTR-1482962 https://reactome.org/PathwayBrowser/#/R-XTR-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Xenopus tropicalis 57876 R-XTR-1483190 https://reactome.org/PathwayBrowser/#/R-XTR-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Xenopus tropicalis 57880 R-BTA-1482598 https://reactome.org/PathwayBrowser/#/R-BTA-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Bos taurus 57880 R-BTA-1482626 https://reactome.org/PathwayBrowser/#/R-BTA-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Bos taurus 57880 R-BTA-1482825 https://reactome.org/PathwayBrowser/#/R-BTA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Bos taurus 57880 R-BTA-1482868 https://reactome.org/PathwayBrowser/#/R-BTA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Bos taurus 57880 R-BTA-1482932 https://reactome.org/PathwayBrowser/#/R-BTA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Bos taurus 57880 R-BTA-1482976 https://reactome.org/PathwayBrowser/#/R-BTA-1482976 CDP-DAG is converted to PI by CDIPT IEA Bos taurus 57880 R-BTA-1483087 https://reactome.org/PathwayBrowser/#/R-BTA-1483087 PI is exchanged with PC by PITPNB IEA Bos taurus 57880 R-BTA-1483219 https://reactome.org/PathwayBrowser/#/R-BTA-1483219 PC is exchanged with PI by PITPNB IEA Bos taurus 57880 R-BTA-1483229 https://reactome.org/PathwayBrowser/#/R-BTA-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Bos taurus 57880 R-BTA-1602377 https://reactome.org/PathwayBrowser/#/R-BTA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Bos taurus 57880 R-BTA-162730 https://reactome.org/PathwayBrowser/#/R-BTA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Bos taurus 57880 R-BTA-1675780 https://reactome.org/PathwayBrowser/#/R-BTA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Bos taurus 57880 R-BTA-1675795 https://reactome.org/PathwayBrowser/#/R-BTA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Bos taurus 57880 R-BTA-1675810 https://reactome.org/PathwayBrowser/#/R-BTA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Bos taurus 57880 R-BTA-1675813 https://reactome.org/PathwayBrowser/#/R-BTA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Bos taurus 57880 R-BTA-1675883 https://reactome.org/PathwayBrowser/#/R-BTA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Bos taurus 57880 R-BTA-1675939 https://reactome.org/PathwayBrowser/#/R-BTA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Bos taurus 57880 R-BTA-1675961 https://reactome.org/PathwayBrowser/#/R-BTA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Bos taurus 57880 R-BTA-1675974 https://reactome.org/PathwayBrowser/#/R-BTA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Bos taurus 57880 R-BTA-1675988 https://reactome.org/PathwayBrowser/#/R-BTA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Bos taurus 57880 R-BTA-1675994 https://reactome.org/PathwayBrowser/#/R-BTA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Bos taurus 57880 R-BTA-1676024 https://reactome.org/PathwayBrowser/#/R-BTA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Bos taurus 57880 R-BTA-1676114 https://reactome.org/PathwayBrowser/#/R-BTA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Bos taurus 57880 R-BTA-1676124 https://reactome.org/PathwayBrowser/#/R-BTA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Bos taurus 57880 R-BTA-1676133 https://reactome.org/PathwayBrowser/#/R-BTA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Bos taurus 57880 R-BTA-1676141 https://reactome.org/PathwayBrowser/#/R-BTA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Bos taurus 57880 R-BTA-1676185 https://reactome.org/PathwayBrowser/#/R-BTA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Bos taurus 57880 R-BTA-2046087 https://reactome.org/PathwayBrowser/#/R-BTA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Bos taurus 57880 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 57880 R-BTA-5672012 https://reactome.org/PathwayBrowser/#/R-BTA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Bos taurus 57880 R-BTA-5679206 https://reactome.org/PathwayBrowser/#/R-BTA-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Bos taurus 57880 R-BTA-6798174 https://reactome.org/PathwayBrowser/#/R-BTA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Bos taurus 57880 R-BTA-6809325 https://reactome.org/PathwayBrowser/#/R-BTA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Bos taurus 57880 R-BTA-6809720 https://reactome.org/PathwayBrowser/#/R-BTA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Bos taurus 57880 R-BTA-6809777 https://reactome.org/PathwayBrowser/#/R-BTA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Bos taurus 57880 R-BTA-8869241 https://reactome.org/PathwayBrowser/#/R-BTA-8869241 PITPNM1,2,3 exchange PI for PA IEA Bos taurus 57880 R-BTA-8940388 https://reactome.org/PathwayBrowser/#/R-BTA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Bos taurus 57880 R-BTA-9794120 https://reactome.org/PathwayBrowser/#/R-BTA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Bos taurus 57880 R-BTA-9794572 https://reactome.org/PathwayBrowser/#/R-BTA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Bos taurus 57880 R-CEL-1482598 https://reactome.org/PathwayBrowser/#/R-CEL-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Caenorhabditis elegans 57880 R-CEL-1482626 https://reactome.org/PathwayBrowser/#/R-CEL-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Caenorhabditis elegans 57880 R-CEL-1482868 https://reactome.org/PathwayBrowser/#/R-CEL-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Caenorhabditis elegans 57880 R-CEL-1482976 https://reactome.org/PathwayBrowser/#/R-CEL-1482976 CDP-DAG is converted to PI by CDIPT IEA Caenorhabditis elegans 57880 R-CEL-1483087 https://reactome.org/PathwayBrowser/#/R-CEL-1483087 PI is exchanged with PC by PITPNB IEA Caenorhabditis elegans 57880 R-CEL-1483219 https://reactome.org/PathwayBrowser/#/R-CEL-1483219 PC is exchanged with PI by PITPNB IEA Caenorhabditis elegans 57880 R-CEL-1483229 https://reactome.org/PathwayBrowser/#/R-CEL-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Caenorhabditis elegans 57880 R-CEL-1602377 https://reactome.org/PathwayBrowser/#/R-CEL-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Caenorhabditis elegans 57880 R-CEL-1675780 https://reactome.org/PathwayBrowser/#/R-CEL-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Caenorhabditis elegans 57880 R-CEL-1675795 https://reactome.org/PathwayBrowser/#/R-CEL-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Caenorhabditis elegans 57880 R-CEL-1675810 https://reactome.org/PathwayBrowser/#/R-CEL-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Caenorhabditis elegans 57880 R-CEL-1675813 https://reactome.org/PathwayBrowser/#/R-CEL-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Caenorhabditis elegans 57880 R-CEL-1675883 https://reactome.org/PathwayBrowser/#/R-CEL-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Caenorhabditis elegans 57880 R-CEL-1675939 https://reactome.org/PathwayBrowser/#/R-CEL-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Caenorhabditis elegans 57880 R-CEL-1675961 https://reactome.org/PathwayBrowser/#/R-CEL-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Caenorhabditis elegans 57880 R-CEL-1675974 https://reactome.org/PathwayBrowser/#/R-CEL-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Caenorhabditis elegans 57880 R-CEL-1675988 https://reactome.org/PathwayBrowser/#/R-CEL-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Caenorhabditis elegans 57880 R-CEL-1675994 https://reactome.org/PathwayBrowser/#/R-CEL-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Caenorhabditis elegans 57880 R-CEL-1676024 https://reactome.org/PathwayBrowser/#/R-CEL-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Caenorhabditis elegans 57880 R-CEL-1676114 https://reactome.org/PathwayBrowser/#/R-CEL-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Caenorhabditis elegans 57880 R-CEL-1676124 https://reactome.org/PathwayBrowser/#/R-CEL-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Caenorhabditis elegans 57880 R-CEL-1676133 https://reactome.org/PathwayBrowser/#/R-CEL-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Caenorhabditis elegans 57880 R-CEL-1676141 https://reactome.org/PathwayBrowser/#/R-CEL-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Caenorhabditis elegans 57880 R-CEL-1676185 https://reactome.org/PathwayBrowser/#/R-CEL-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Caenorhabditis elegans 57880 R-CEL-2046087 https://reactome.org/PathwayBrowser/#/R-CEL-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Caenorhabditis elegans 57880 R-CEL-5672012 https://reactome.org/PathwayBrowser/#/R-CEL-5672012 Beclin-1 complex phosphorylates PtdIns IEA Caenorhabditis elegans 57880 R-CEL-6798174 https://reactome.org/PathwayBrowser/#/R-CEL-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Caenorhabditis elegans 57880 R-CEL-6809325 https://reactome.org/PathwayBrowser/#/R-CEL-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Caenorhabditis elegans 57880 R-CEL-6809720 https://reactome.org/PathwayBrowser/#/R-CEL-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Caenorhabditis elegans 57880 R-CEL-6809777 https://reactome.org/PathwayBrowser/#/R-CEL-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Caenorhabditis elegans 57880 R-CEL-8869241 https://reactome.org/PathwayBrowser/#/R-CEL-8869241 PITPNM1,2,3 exchange PI for PA IEA Caenorhabditis elegans 57880 R-CEL-9794120 https://reactome.org/PathwayBrowser/#/R-CEL-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Caenorhabditis elegans 57880 R-CEL-9794572 https://reactome.org/PathwayBrowser/#/R-CEL-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Caenorhabditis elegans 57880 R-CFA-1482598 https://reactome.org/PathwayBrowser/#/R-CFA-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Canis familiaris 57880 R-CFA-1482626 https://reactome.org/PathwayBrowser/#/R-CFA-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Canis familiaris 57880 R-CFA-1482825 https://reactome.org/PathwayBrowser/#/R-CFA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Canis familiaris 57880 R-CFA-1482932 https://reactome.org/PathwayBrowser/#/R-CFA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Canis familiaris 57880 R-CFA-1482976 https://reactome.org/PathwayBrowser/#/R-CFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Canis familiaris 57880 R-CFA-1483087 https://reactome.org/PathwayBrowser/#/R-CFA-1483087 PI is exchanged with PC by PITPNB IEA Canis familiaris 57880 R-CFA-1483219 https://reactome.org/PathwayBrowser/#/R-CFA-1483219 PC is exchanged with PI by PITPNB IEA Canis familiaris 57880 R-CFA-1483229 https://reactome.org/PathwayBrowser/#/R-CFA-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Canis familiaris 57880 R-CFA-1602377 https://reactome.org/PathwayBrowser/#/R-CFA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Canis familiaris 57880 R-CFA-1675780 https://reactome.org/PathwayBrowser/#/R-CFA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Canis familiaris 57880 R-CFA-1675795 https://reactome.org/PathwayBrowser/#/R-CFA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Canis familiaris 57880 R-CFA-1675810 https://reactome.org/PathwayBrowser/#/R-CFA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Canis familiaris 57880 R-CFA-1675813 https://reactome.org/PathwayBrowser/#/R-CFA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Canis familiaris 57880 R-CFA-1675883 https://reactome.org/PathwayBrowser/#/R-CFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Canis familiaris 57880 R-CFA-1675939 https://reactome.org/PathwayBrowser/#/R-CFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Canis familiaris 57880 R-CFA-1675961 https://reactome.org/PathwayBrowser/#/R-CFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Canis familiaris 57880 R-CFA-1675974 https://reactome.org/PathwayBrowser/#/R-CFA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Canis familiaris 57880 R-CFA-1675988 https://reactome.org/PathwayBrowser/#/R-CFA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Canis familiaris 57880 R-CFA-1675994 https://reactome.org/PathwayBrowser/#/R-CFA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Canis familiaris 57880 R-CFA-1676024 https://reactome.org/PathwayBrowser/#/R-CFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Canis familiaris 57880 R-CFA-1676114 https://reactome.org/PathwayBrowser/#/R-CFA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Canis familiaris 57880 R-CFA-1676124 https://reactome.org/PathwayBrowser/#/R-CFA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Canis familiaris 57880 R-CFA-1676133 https://reactome.org/PathwayBrowser/#/R-CFA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Canis familiaris 57880 R-CFA-1676141 https://reactome.org/PathwayBrowser/#/R-CFA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Canis familiaris 57880 R-CFA-1676185 https://reactome.org/PathwayBrowser/#/R-CFA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Canis familiaris 57880 R-CFA-2046087 https://reactome.org/PathwayBrowser/#/R-CFA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Canis familiaris 57880 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 57880 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 57880 R-CFA-5672012 https://reactome.org/PathwayBrowser/#/R-CFA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Canis familiaris 57880 R-CFA-5679206 https://reactome.org/PathwayBrowser/#/R-CFA-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Canis familiaris 57880 R-CFA-6798174 https://reactome.org/PathwayBrowser/#/R-CFA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Canis familiaris 57880 R-CFA-6809325 https://reactome.org/PathwayBrowser/#/R-CFA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Canis familiaris 57880 R-CFA-6809720 https://reactome.org/PathwayBrowser/#/R-CFA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Canis familiaris 57880 R-CFA-6809777 https://reactome.org/PathwayBrowser/#/R-CFA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Canis familiaris 57880 R-CFA-8869241 https://reactome.org/PathwayBrowser/#/R-CFA-8869241 PITPNM1,2,3 exchange PI for PA IEA Canis familiaris 57880 R-CFA-8940388 https://reactome.org/PathwayBrowser/#/R-CFA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Canis familiaris 57880 R-CFA-9794120 https://reactome.org/PathwayBrowser/#/R-CFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Canis familiaris 57880 R-CFA-9794572 https://reactome.org/PathwayBrowser/#/R-CFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Canis familiaris 57880 R-DDI-1482598 https://reactome.org/PathwayBrowser/#/R-DDI-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Dictyostelium discoideum 57880 R-DDI-1482626 https://reactome.org/PathwayBrowser/#/R-DDI-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Dictyostelium discoideum 57880 R-DDI-1482825 https://reactome.org/PathwayBrowser/#/R-DDI-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Dictyostelium discoideum 57880 R-DDI-1482976 https://reactome.org/PathwayBrowser/#/R-DDI-1482976 CDP-DAG is converted to PI by CDIPT IEA Dictyostelium discoideum 57880 R-DDI-1483087 https://reactome.org/PathwayBrowser/#/R-DDI-1483087 PI is exchanged with PC by PITPNB IEA Dictyostelium discoideum 57880 R-DDI-1483219 https://reactome.org/PathwayBrowser/#/R-DDI-1483219 PC is exchanged with PI by PITPNB IEA Dictyostelium discoideum 57880 R-DDI-1483229 https://reactome.org/PathwayBrowser/#/R-DDI-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Dictyostelium discoideum 57880 R-DDI-1675795 https://reactome.org/PathwayBrowser/#/R-DDI-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Dictyostelium discoideum 57880 R-DDI-1675810 https://reactome.org/PathwayBrowser/#/R-DDI-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Dictyostelium discoideum 57880 R-DDI-1675813 https://reactome.org/PathwayBrowser/#/R-DDI-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Dictyostelium discoideum 57880 R-DDI-1675883 https://reactome.org/PathwayBrowser/#/R-DDI-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Dictyostelium discoideum 57880 R-DDI-1675939 https://reactome.org/PathwayBrowser/#/R-DDI-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Dictyostelium discoideum 57880 R-DDI-1675961 https://reactome.org/PathwayBrowser/#/R-DDI-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Dictyostelium discoideum 57880 R-DDI-1675988 https://reactome.org/PathwayBrowser/#/R-DDI-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Dictyostelium discoideum 57880 R-DDI-1675994 https://reactome.org/PathwayBrowser/#/R-DDI-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Dictyostelium discoideum 57880 R-DDI-1676024 https://reactome.org/PathwayBrowser/#/R-DDI-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Dictyostelium discoideum 57880 R-DDI-1676114 https://reactome.org/PathwayBrowser/#/R-DDI-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Dictyostelium discoideum 57880 R-DDI-1676124 https://reactome.org/PathwayBrowser/#/R-DDI-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Dictyostelium discoideum 57880 R-DDI-1676133 https://reactome.org/PathwayBrowser/#/R-DDI-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Dictyostelium discoideum 57880 R-DDI-1676141 https://reactome.org/PathwayBrowser/#/R-DDI-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Dictyostelium discoideum 57880 R-DDI-1676185 https://reactome.org/PathwayBrowser/#/R-DDI-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Dictyostelium discoideum 57880 R-DDI-2046087 https://reactome.org/PathwayBrowser/#/R-DDI-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Dictyostelium discoideum 57880 R-DDI-5672012 https://reactome.org/PathwayBrowser/#/R-DDI-5672012 Beclin-1 complex phosphorylates PtdIns IEA Dictyostelium discoideum 57880 R-DDI-5679206 https://reactome.org/PathwayBrowser/#/R-DDI-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Dictyostelium discoideum 57880 R-DDI-6798174 https://reactome.org/PathwayBrowser/#/R-DDI-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Dictyostelium discoideum 57880 R-DDI-6809325 https://reactome.org/PathwayBrowser/#/R-DDI-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Dictyostelium discoideum 57880 R-DDI-6809720 https://reactome.org/PathwayBrowser/#/R-DDI-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Dictyostelium discoideum 57880 R-DDI-6809777 https://reactome.org/PathwayBrowser/#/R-DDI-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Dictyostelium discoideum 57880 R-DDI-8869241 https://reactome.org/PathwayBrowser/#/R-DDI-8869241 PITPNM1,2,3 exchange PI for PA IEA Dictyostelium discoideum 57880 R-DDI-8940388 https://reactome.org/PathwayBrowser/#/R-DDI-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Dictyostelium discoideum 57880 R-DDI-9794120 https://reactome.org/PathwayBrowser/#/R-DDI-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Dictyostelium discoideum 57880 R-DDI-9794572 https://reactome.org/PathwayBrowser/#/R-DDI-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Dictyostelium discoideum 57880 R-DME-1482598 https://reactome.org/PathwayBrowser/#/R-DME-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Drosophila melanogaster 57880 R-DME-1482626 https://reactome.org/PathwayBrowser/#/R-DME-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Drosophila melanogaster 57880 R-DME-1482868 https://reactome.org/PathwayBrowser/#/R-DME-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Drosophila melanogaster 57880 R-DME-1482976 https://reactome.org/PathwayBrowser/#/R-DME-1482976 CDP-DAG is converted to PI by CDIPT IEA Drosophila melanogaster 57880 R-DME-1483087 https://reactome.org/PathwayBrowser/#/R-DME-1483087 PI is exchanged with PC by PITPNB IEA Drosophila melanogaster 57880 R-DME-1483219 https://reactome.org/PathwayBrowser/#/R-DME-1483219 PC is exchanged with PI by PITPNB IEA Drosophila melanogaster 57880 R-DME-1483229 https://reactome.org/PathwayBrowser/#/R-DME-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Drosophila melanogaster 57880 R-DME-1602377 https://reactome.org/PathwayBrowser/#/R-DME-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Drosophila melanogaster 57880 R-DME-1675780 https://reactome.org/PathwayBrowser/#/R-DME-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Drosophila melanogaster 57880 R-DME-1675795 https://reactome.org/PathwayBrowser/#/R-DME-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Drosophila melanogaster 57880 R-DME-1675810 https://reactome.org/PathwayBrowser/#/R-DME-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Drosophila melanogaster 57880 R-DME-1675813 https://reactome.org/PathwayBrowser/#/R-DME-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Drosophila melanogaster 57880 R-DME-1675883 https://reactome.org/PathwayBrowser/#/R-DME-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Drosophila melanogaster 57880 R-DME-1675939 https://reactome.org/PathwayBrowser/#/R-DME-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Drosophila melanogaster 57880 R-DME-1675961 https://reactome.org/PathwayBrowser/#/R-DME-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Drosophila melanogaster 57880 R-DME-1675974 https://reactome.org/PathwayBrowser/#/R-DME-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Drosophila melanogaster 57880 R-DME-1675988 https://reactome.org/PathwayBrowser/#/R-DME-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Drosophila melanogaster 57880 R-DME-1675994 https://reactome.org/PathwayBrowser/#/R-DME-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Drosophila melanogaster 57880 R-DME-1676024 https://reactome.org/PathwayBrowser/#/R-DME-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Drosophila melanogaster 57880 R-DME-1676114 https://reactome.org/PathwayBrowser/#/R-DME-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Drosophila melanogaster 57880 R-DME-1676124 https://reactome.org/PathwayBrowser/#/R-DME-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Drosophila melanogaster 57880 R-DME-1676133 https://reactome.org/PathwayBrowser/#/R-DME-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Drosophila melanogaster 57880 R-DME-1676141 https://reactome.org/PathwayBrowser/#/R-DME-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Drosophila melanogaster 57880 R-DME-1676185 https://reactome.org/PathwayBrowser/#/R-DME-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Drosophila melanogaster 57880 R-DME-2046087 https://reactome.org/PathwayBrowser/#/R-DME-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Drosophila melanogaster 57880 R-DME-5672012 https://reactome.org/PathwayBrowser/#/R-DME-5672012 Beclin-1 complex phosphorylates PtdIns IEA Drosophila melanogaster 57880 R-DME-5679206 https://reactome.org/PathwayBrowser/#/R-DME-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Drosophila melanogaster 57880 R-DME-6798174 https://reactome.org/PathwayBrowser/#/R-DME-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Drosophila melanogaster 57880 R-DME-6809325 https://reactome.org/PathwayBrowser/#/R-DME-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Drosophila melanogaster 57880 R-DME-6809720 https://reactome.org/PathwayBrowser/#/R-DME-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Drosophila melanogaster 57880 R-DME-6809777 https://reactome.org/PathwayBrowser/#/R-DME-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Drosophila melanogaster 57880 R-DME-8869241 https://reactome.org/PathwayBrowser/#/R-DME-8869241 PITPNM1,2,3 exchange PI for PA IEA Drosophila melanogaster 57880 R-DME-9794120 https://reactome.org/PathwayBrowser/#/R-DME-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Drosophila melanogaster 57880 R-DME-9794572 https://reactome.org/PathwayBrowser/#/R-DME-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Drosophila melanogaster 57880 R-DRE-1482598 https://reactome.org/PathwayBrowser/#/R-DRE-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Danio rerio 57880 R-DRE-1482626 https://reactome.org/PathwayBrowser/#/R-DRE-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Danio rerio 57880 R-DRE-1482825 https://reactome.org/PathwayBrowser/#/R-DRE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Danio rerio 57880 R-DRE-1482868 https://reactome.org/PathwayBrowser/#/R-DRE-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Danio rerio 57880 R-DRE-1482976 https://reactome.org/PathwayBrowser/#/R-DRE-1482976 CDP-DAG is converted to PI by CDIPT IEA Danio rerio 57880 R-DRE-1602377 https://reactome.org/PathwayBrowser/#/R-DRE-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Danio rerio 57880 R-DRE-1675780 https://reactome.org/PathwayBrowser/#/R-DRE-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Danio rerio 57880 R-DRE-1675795 https://reactome.org/PathwayBrowser/#/R-DRE-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Danio rerio 57880 R-DRE-1675810 https://reactome.org/PathwayBrowser/#/R-DRE-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Danio rerio 57880 R-DRE-1675813 https://reactome.org/PathwayBrowser/#/R-DRE-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Danio rerio 57880 R-DRE-1675883 https://reactome.org/PathwayBrowser/#/R-DRE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Danio rerio 57880 R-DRE-1675974 https://reactome.org/PathwayBrowser/#/R-DRE-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Danio rerio 57880 R-DRE-1675994 https://reactome.org/PathwayBrowser/#/R-DRE-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Danio rerio 57880 R-DRE-1676114 https://reactome.org/PathwayBrowser/#/R-DRE-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Danio rerio 57880 R-DRE-1676124 https://reactome.org/PathwayBrowser/#/R-DRE-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Danio rerio 57880 R-DRE-1676133 https://reactome.org/PathwayBrowser/#/R-DRE-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Danio rerio 57880 R-DRE-1676141 https://reactome.org/PathwayBrowser/#/R-DRE-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Danio rerio 57880 R-DRE-1676185 https://reactome.org/PathwayBrowser/#/R-DRE-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Danio rerio 57880 R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 57880 R-DRE-6809325 https://reactome.org/PathwayBrowser/#/R-DRE-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Danio rerio 57880 R-DRE-6809720 https://reactome.org/PathwayBrowser/#/R-DRE-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Danio rerio 57880 R-GGA-1482825 https://reactome.org/PathwayBrowser/#/R-GGA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Gallus gallus 57880 R-GGA-1482868 https://reactome.org/PathwayBrowser/#/R-GGA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Gallus gallus 57880 R-GGA-1482932 https://reactome.org/PathwayBrowser/#/R-GGA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Gallus gallus 57880 R-GGA-1483087 https://reactome.org/PathwayBrowser/#/R-GGA-1483087 PI is exchanged with PC by PITPNB IEA Gallus gallus 57880 R-GGA-1483219 https://reactome.org/PathwayBrowser/#/R-GGA-1483219 PC is exchanged with PI by PITPNB IEA Gallus gallus 57880 R-GGA-1483229 https://reactome.org/PathwayBrowser/#/R-GGA-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Gallus gallus 57880 R-GGA-1602377 https://reactome.org/PathwayBrowser/#/R-GGA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Gallus gallus 57880 R-GGA-162730 https://reactome.org/PathwayBrowser/#/R-GGA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Gallus gallus 57880 R-GGA-1675780 https://reactome.org/PathwayBrowser/#/R-GGA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Gallus gallus 57880 R-GGA-1675795 https://reactome.org/PathwayBrowser/#/R-GGA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Gallus gallus 57880 R-GGA-1675810 https://reactome.org/PathwayBrowser/#/R-GGA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Gallus gallus 57880 R-GGA-1675813 https://reactome.org/PathwayBrowser/#/R-GGA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Gallus gallus 57880 R-GGA-1675883 https://reactome.org/PathwayBrowser/#/R-GGA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Gallus gallus 57880 R-GGA-1675939 https://reactome.org/PathwayBrowser/#/R-GGA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Gallus gallus 57880 R-GGA-1675961 https://reactome.org/PathwayBrowser/#/R-GGA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Gallus gallus 57880 R-GGA-1675974 https://reactome.org/PathwayBrowser/#/R-GGA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Gallus gallus 57880 R-GGA-1675988 https://reactome.org/PathwayBrowser/#/R-GGA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Gallus gallus 57880 R-GGA-1675994 https://reactome.org/PathwayBrowser/#/R-GGA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Gallus gallus 57880 R-GGA-1676024 https://reactome.org/PathwayBrowser/#/R-GGA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Gallus gallus 57880 R-GGA-1676114 https://reactome.org/PathwayBrowser/#/R-GGA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Gallus gallus 57880 R-GGA-1676124 https://reactome.org/PathwayBrowser/#/R-GGA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Gallus gallus 57880 R-GGA-1676133 https://reactome.org/PathwayBrowser/#/R-GGA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Gallus gallus 57880 R-GGA-1676141 https://reactome.org/PathwayBrowser/#/R-GGA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Gallus gallus 57880 R-GGA-1676185 https://reactome.org/PathwayBrowser/#/R-GGA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Gallus gallus 57880 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 57880 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 57880 R-GGA-5672012 https://reactome.org/PathwayBrowser/#/R-GGA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Gallus gallus 57880 R-GGA-5679206 https://reactome.org/PathwayBrowser/#/R-GGA-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Gallus gallus 57880 R-GGA-6798174 https://reactome.org/PathwayBrowser/#/R-GGA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Gallus gallus 57880 R-GGA-6809325 https://reactome.org/PathwayBrowser/#/R-GGA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Gallus gallus 57880 R-GGA-6809720 https://reactome.org/PathwayBrowser/#/R-GGA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Gallus gallus 57880 R-GGA-6809777 https://reactome.org/PathwayBrowser/#/R-GGA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Gallus gallus 57880 R-GGA-8869241 https://reactome.org/PathwayBrowser/#/R-GGA-8869241 PITPNM1,2,3 exchange PI for PA IEA Gallus gallus 57880 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus 57880 R-HSA-1482598 https://reactome.org/PathwayBrowser/#/R-HSA-1482598 1-acyl LPI is acylated to PI by MBOAT7 TAS Homo sapiens 57880 R-HSA-1482626 https://reactome.org/PathwayBrowser/#/R-HSA-1482626 2-acyl LPI is acylated to PI by MBOAT7 TAS Homo sapiens 57880 R-HSA-1482825 https://reactome.org/PathwayBrowser/#/R-HSA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] TAS Homo sapiens 57880 R-HSA-1482868 https://reactome.org/PathwayBrowser/#/R-HSA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] TAS Homo sapiens 57880 R-HSA-1482932 https://reactome.org/PathwayBrowser/#/R-HSA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] TAS Homo sapiens 57880 R-HSA-1482976 https://reactome.org/PathwayBrowser/#/R-HSA-1482976 CDP-DAG is converted to PI by CDIPT TAS Homo sapiens 57880 R-HSA-1483087 https://reactome.org/PathwayBrowser/#/R-HSA-1483087 PI is exchanged with PC by PITPNB TAS Homo sapiens 57880 R-HSA-1483219 https://reactome.org/PathwayBrowser/#/R-HSA-1483219 PC is exchanged with PI by PITPNB TAS Homo sapiens 57880 R-HSA-1483229 https://reactome.org/PathwayBrowser/#/R-HSA-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane TAS Homo sapiens 57880 R-HSA-1602377 https://reactome.org/PathwayBrowser/#/R-HSA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] TAS Homo sapiens 57880 R-HSA-162730 https://reactome.org/PathwayBrowser/#/R-HSA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP TAS Homo sapiens 57880 R-HSA-1675780 https://reactome.org/PathwayBrowser/#/R-HSA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane TAS Homo sapiens 57880 R-HSA-1675795 https://reactome.org/PathwayBrowser/#/R-HSA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane TAS Homo sapiens 57880 R-HSA-1675810 https://reactome.org/PathwayBrowser/#/R-HSA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane TAS Homo sapiens 57880 R-HSA-1675813 https://reactome.org/PathwayBrowser/#/R-HSA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane TAS Homo sapiens 57880 R-HSA-1675866 https://reactome.org/PathwayBrowser/#/R-HSA-1675866 PI is phosphorylated to PI5P by PIKFYVE at the late endosome membrane IEA Homo sapiens 57880 R-HSA-1675883 https://reactome.org/PathwayBrowser/#/R-HSA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane TAS Homo sapiens 57880 R-HSA-1675939 https://reactome.org/PathwayBrowser/#/R-HSA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane TAS Homo sapiens 57880 R-HSA-1675961 https://reactome.org/PathwayBrowser/#/R-HSA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane TAS Homo sapiens 57880 R-HSA-1675974 https://reactome.org/PathwayBrowser/#/R-HSA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane TAS Homo sapiens 57880 R-HSA-1675988 https://reactome.org/PathwayBrowser/#/R-HSA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane TAS Homo sapiens 57880 R-HSA-1675994 https://reactome.org/PathwayBrowser/#/R-HSA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane TAS Homo sapiens 57880 R-HSA-1676024 https://reactome.org/PathwayBrowser/#/R-HSA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane TAS Homo sapiens 57880 R-HSA-1676114 https://reactome.org/PathwayBrowser/#/R-HSA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane TAS Homo sapiens 57880 R-HSA-1676124 https://reactome.org/PathwayBrowser/#/R-HSA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane TAS Homo sapiens 57880 R-HSA-1676133 https://reactome.org/PathwayBrowser/#/R-HSA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane TAS Homo sapiens 57880 R-HSA-1676141 https://reactome.org/PathwayBrowser/#/R-HSA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane TAS Homo sapiens 57880 R-HSA-1676185 https://reactome.org/PathwayBrowser/#/R-HSA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane TAS Homo sapiens 57880 R-HSA-2046087 https://reactome.org/PathwayBrowser/#/R-HSA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes TAS Homo sapiens 57880 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 57880 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 57880 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 57880 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 57880 R-HSA-5672012 https://reactome.org/PathwayBrowser/#/R-HSA-5672012 Beclin-1 complex phosphorylates PtdIns TAS Homo sapiens 57880 R-HSA-5679206 https://reactome.org/PathwayBrowser/#/R-HSA-5679206 MTMR14, MTMR3 dephosphorylate PI3P TAS Homo sapiens 57880 R-HSA-6798174 https://reactome.org/PathwayBrowser/#/R-HSA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P TAS Homo sapiens 57880 R-HSA-6809325 https://reactome.org/PathwayBrowser/#/R-HSA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane TAS Homo sapiens 57880 R-HSA-6809720 https://reactome.org/PathwayBrowser/#/R-HSA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 TAS Homo sapiens 57880 R-HSA-6809777 https://reactome.org/PathwayBrowser/#/R-HSA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 TAS Homo sapiens 57880 R-HSA-6809975 https://reactome.org/PathwayBrowser/#/R-HSA-6809975 PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane IEA Homo sapiens 57880 R-HSA-8869241 https://reactome.org/PathwayBrowser/#/R-HSA-8869241 PITPNM1,2,3 exchange PI for PA TAS Homo sapiens 57880 R-HSA-8940388 https://reactome.org/PathwayBrowser/#/R-HSA-8940388 GPLD1 hydrolyses GPI-anchors from proteins TAS Homo sapiens 57880 R-HSA-9636457 https://reactome.org/PathwayBrowser/#/R-HSA-9636457 SapM dephosphorylates PI3P TAS Homo sapiens 57880 R-HSA-9794120 https://reactome.org/PathwayBrowser/#/R-HSA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space TAS Homo sapiens 57880 R-HSA-9794572 https://reactome.org/PathwayBrowser/#/R-HSA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space TAS Homo sapiens 57880 R-MMU-1482598 https://reactome.org/PathwayBrowser/#/R-MMU-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Mus musculus 57880 R-MMU-1482626 https://reactome.org/PathwayBrowser/#/R-MMU-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Mus musculus 57880 R-MMU-1482825 https://reactome.org/PathwayBrowser/#/R-MMU-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Mus musculus 57880 R-MMU-1482868 https://reactome.org/PathwayBrowser/#/R-MMU-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Mus musculus 57880 R-MMU-1482932 https://reactome.org/PathwayBrowser/#/R-MMU-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Mus musculus 57880 R-MMU-1482976 https://reactome.org/PathwayBrowser/#/R-MMU-1482976 CDP-DAG is converted to PI by CDIPT IEA Mus musculus 57880 R-MMU-1483087 https://reactome.org/PathwayBrowser/#/R-MMU-1483087 PI is exchanged with PC by PITPNB IEA Mus musculus 57880 R-MMU-1483219 https://reactome.org/PathwayBrowser/#/R-MMU-1483219 PC is exchanged with PI by PITPNB IEA Mus musculus 57880 R-MMU-1483229 https://reactome.org/PathwayBrowser/#/R-MMU-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Mus musculus 57880 R-MMU-1602377 https://reactome.org/PathwayBrowser/#/R-MMU-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Mus musculus 57880 R-MMU-162730 https://reactome.org/PathwayBrowser/#/R-MMU-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Mus musculus 57880 R-MMU-1675780 https://reactome.org/PathwayBrowser/#/R-MMU-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Mus musculus 57880 R-MMU-1675795 https://reactome.org/PathwayBrowser/#/R-MMU-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Mus musculus 57880 R-MMU-1675810 https://reactome.org/PathwayBrowser/#/R-MMU-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Mus musculus 57880 R-MMU-1675813 https://reactome.org/PathwayBrowser/#/R-MMU-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Mus musculus 57880 R-MMU-1675883 https://reactome.org/PathwayBrowser/#/R-MMU-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Mus musculus 57880 R-MMU-1675939 https://reactome.org/PathwayBrowser/#/R-MMU-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Mus musculus 57880 R-MMU-1675961 https://reactome.org/PathwayBrowser/#/R-MMU-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Mus musculus 57880 R-MMU-1675974 https://reactome.org/PathwayBrowser/#/R-MMU-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Mus musculus 57880 R-MMU-1675988 https://reactome.org/PathwayBrowser/#/R-MMU-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Mus musculus 57880 R-MMU-1675994 https://reactome.org/PathwayBrowser/#/R-MMU-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Mus musculus 57880 R-MMU-1676024 https://reactome.org/PathwayBrowser/#/R-MMU-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Mus musculus 57880 R-MMU-1676114 https://reactome.org/PathwayBrowser/#/R-MMU-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Mus musculus 57880 R-MMU-1676124 https://reactome.org/PathwayBrowser/#/R-MMU-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Mus musculus 57880 R-MMU-1676133 https://reactome.org/PathwayBrowser/#/R-MMU-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Mus musculus 57880 R-MMU-1676141 https://reactome.org/PathwayBrowser/#/R-MMU-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Mus musculus 57880 R-MMU-1676185 https://reactome.org/PathwayBrowser/#/R-MMU-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Mus musculus 57880 R-MMU-2046087 https://reactome.org/PathwayBrowser/#/R-MMU-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Mus musculus 57880 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 57880 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 57880 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 57880 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 57880 R-MMU-5672012 https://reactome.org/PathwayBrowser/#/R-MMU-5672012 Beclin-1 complex phosphorylates PtdIns IEA Mus musculus 57880 R-MMU-5679206 https://reactome.org/PathwayBrowser/#/R-MMU-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Mus musculus 57880 R-MMU-6798174 https://reactome.org/PathwayBrowser/#/R-MMU-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Mus musculus 57880 R-MMU-6809325 https://reactome.org/PathwayBrowser/#/R-MMU-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Mus musculus 57880 R-MMU-6809720 https://reactome.org/PathwayBrowser/#/R-MMU-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Mus musculus 57880 R-MMU-6809777 https://reactome.org/PathwayBrowser/#/R-MMU-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Mus musculus 57880 R-MMU-6809977 https://reactome.org/PathwayBrowser/#/R-MMU-6809977 PI3P is dephosphorylated to PI by the Mtmr2:Sbf2 tetramer at the plasma membrane TAS Mus musculus 57880 R-MMU-8869241 https://reactome.org/PathwayBrowser/#/R-MMU-8869241 PITPNM1,2,3 exchange PI for PA IEA Mus musculus 57880 R-MMU-8940388 https://reactome.org/PathwayBrowser/#/R-MMU-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Mus musculus 57880 R-MMU-9794120 https://reactome.org/PathwayBrowser/#/R-MMU-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Mus musculus 57880 R-MMU-9794572 https://reactome.org/PathwayBrowser/#/R-MMU-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Mus musculus 57880 R-NUL-1676051 https://reactome.org/PathwayBrowser/#/R-NUL-1676051 PI is phosphorylated to PI5P by Pikfyve at the late endosome membrane TAS Mus musculus 57880 R-PFA-1482976 https://reactome.org/PathwayBrowser/#/R-PFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Plasmodium falciparum 57880 R-PFA-1483087 https://reactome.org/PathwayBrowser/#/R-PFA-1483087 PI is exchanged with PC by PITPNB IEA Plasmodium falciparum 57880 R-PFA-1483219 https://reactome.org/PathwayBrowser/#/R-PFA-1483219 PC is exchanged with PI by PITPNB IEA Plasmodium falciparum 57880 R-PFA-1483229 https://reactome.org/PathwayBrowser/#/R-PFA-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Plasmodium falciparum 57880 R-PFA-1675810 https://reactome.org/PathwayBrowser/#/R-PFA-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Plasmodium falciparum 57880 R-PFA-1675883 https://reactome.org/PathwayBrowser/#/R-PFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Plasmodium falciparum 57880 R-PFA-1675939 https://reactome.org/PathwayBrowser/#/R-PFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Plasmodium falciparum 57880 R-PFA-1675961 https://reactome.org/PathwayBrowser/#/R-PFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Plasmodium falciparum 57880 R-PFA-1675988 https://reactome.org/PathwayBrowser/#/R-PFA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Plasmodium falciparum 57880 R-PFA-1675994 https://reactome.org/PathwayBrowser/#/R-PFA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Plasmodium falciparum 57880 R-PFA-1676024 https://reactome.org/PathwayBrowser/#/R-PFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Plasmodium falciparum 57880 R-PFA-1676114 https://reactome.org/PathwayBrowser/#/R-PFA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Plasmodium falciparum 57880 R-PFA-1676124 https://reactome.org/PathwayBrowser/#/R-PFA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Plasmodium falciparum 57880 R-PFA-1676133 https://reactome.org/PathwayBrowser/#/R-PFA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Plasmodium falciparum 57880 R-PFA-6798174 https://reactome.org/PathwayBrowser/#/R-PFA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Plasmodium falciparum 57880 R-PFA-8869241 https://reactome.org/PathwayBrowser/#/R-PFA-8869241 PITPNM1,2,3 exchange PI for PA IEA Plasmodium falciparum 57880 R-PFA-9794120 https://reactome.org/PathwayBrowser/#/R-PFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Plasmodium falciparum 57880 R-PFA-9794572 https://reactome.org/PathwayBrowser/#/R-PFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Plasmodium falciparum 57880 R-RNO-1482825 https://reactome.org/PathwayBrowser/#/R-RNO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Rattus norvegicus 57880 R-RNO-1482868 https://reactome.org/PathwayBrowser/#/R-RNO-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Rattus norvegicus 57880 R-RNO-1482932 https://reactome.org/PathwayBrowser/#/R-RNO-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Rattus norvegicus 57880 R-RNO-1482976 https://reactome.org/PathwayBrowser/#/R-RNO-1482976 CDP-DAG is converted to PI by CDIPT IEA Rattus norvegicus 57880 R-RNO-1483087 https://reactome.org/PathwayBrowser/#/R-RNO-1483087 PI is exchanged with PC by PITPNB IEA Rattus norvegicus 57880 R-RNO-1483219 https://reactome.org/PathwayBrowser/#/R-RNO-1483219 PC is exchanged with PI by PITPNB IEA Rattus norvegicus 57880 R-RNO-1483229 https://reactome.org/PathwayBrowser/#/R-RNO-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Rattus norvegicus 57880 R-RNO-1602377 https://reactome.org/PathwayBrowser/#/R-RNO-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Rattus norvegicus 57880 R-RNO-162730 https://reactome.org/PathwayBrowser/#/R-RNO-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Rattus norvegicus 57880 R-RNO-1675780 https://reactome.org/PathwayBrowser/#/R-RNO-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Rattus norvegicus 57880 R-RNO-1675795 https://reactome.org/PathwayBrowser/#/R-RNO-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Rattus norvegicus 57880 R-RNO-1675810 https://reactome.org/PathwayBrowser/#/R-RNO-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Rattus norvegicus 57880 R-RNO-1675813 https://reactome.org/PathwayBrowser/#/R-RNO-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Rattus norvegicus 57880 R-RNO-1675883 https://reactome.org/PathwayBrowser/#/R-RNO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Rattus norvegicus 57880 R-RNO-1675939 https://reactome.org/PathwayBrowser/#/R-RNO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Rattus norvegicus 57880 R-RNO-1675961 https://reactome.org/PathwayBrowser/#/R-RNO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Rattus norvegicus 57880 R-RNO-1675974 https://reactome.org/PathwayBrowser/#/R-RNO-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Rattus norvegicus 57880 R-RNO-1675988 https://reactome.org/PathwayBrowser/#/R-RNO-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Rattus norvegicus 57880 R-RNO-1675994 https://reactome.org/PathwayBrowser/#/R-RNO-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus 57880 R-RNO-1676024 https://reactome.org/PathwayBrowser/#/R-RNO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Rattus norvegicus 57880 R-RNO-1676114 https://reactome.org/PathwayBrowser/#/R-RNO-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Rattus norvegicus 57880 R-RNO-1676124 https://reactome.org/PathwayBrowser/#/R-RNO-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Rattus norvegicus 57880 R-RNO-1676133 https://reactome.org/PathwayBrowser/#/R-RNO-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Rattus norvegicus 57880 R-RNO-1676141 https://reactome.org/PathwayBrowser/#/R-RNO-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Rattus norvegicus 57880 R-RNO-1676185 https://reactome.org/PathwayBrowser/#/R-RNO-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Rattus norvegicus 57880 R-RNO-2046087 https://reactome.org/PathwayBrowser/#/R-RNO-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Rattus norvegicus 57880 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 57880 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 57880 R-RNO-5672012 https://reactome.org/PathwayBrowser/#/R-RNO-5672012 Beclin-1 complex phosphorylates PtdIns IEA Rattus norvegicus 57880 R-RNO-5679206 https://reactome.org/PathwayBrowser/#/R-RNO-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Rattus norvegicus 57880 R-RNO-6798174 https://reactome.org/PathwayBrowser/#/R-RNO-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Rattus norvegicus 57880 R-RNO-6809325 https://reactome.org/PathwayBrowser/#/R-RNO-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Rattus norvegicus 57880 R-RNO-6809720 https://reactome.org/PathwayBrowser/#/R-RNO-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Rattus norvegicus 57880 R-RNO-6809777 https://reactome.org/PathwayBrowser/#/R-RNO-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Rattus norvegicus 57880 R-RNO-8869241 https://reactome.org/PathwayBrowser/#/R-RNO-8869241 PITPNM1,2,3 exchange PI for PA IEA Rattus norvegicus 57880 R-RNO-8940388 https://reactome.org/PathwayBrowser/#/R-RNO-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Rattus norvegicus 57880 R-RNO-9794120 https://reactome.org/PathwayBrowser/#/R-RNO-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Rattus norvegicus 57880 R-RNO-9794572 https://reactome.org/PathwayBrowser/#/R-RNO-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Rattus norvegicus 57880 R-SCE-1482598 https://reactome.org/PathwayBrowser/#/R-SCE-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Saccharomyces cerevisiae 57880 R-SCE-1482626 https://reactome.org/PathwayBrowser/#/R-SCE-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Saccharomyces cerevisiae 57880 R-SCE-1482825 https://reactome.org/PathwayBrowser/#/R-SCE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Saccharomyces cerevisiae 57880 R-SCE-1482868 https://reactome.org/PathwayBrowser/#/R-SCE-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Saccharomyces cerevisiae 57880 R-SCE-1482932 https://reactome.org/PathwayBrowser/#/R-SCE-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Saccharomyces cerevisiae 57880 R-SCE-1482976 https://reactome.org/PathwayBrowser/#/R-SCE-1482976 CDP-DAG is converted to PI by CDIPT IEA Saccharomyces cerevisiae 57880 R-SCE-1675780 https://reactome.org/PathwayBrowser/#/R-SCE-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1675795 https://reactome.org/PathwayBrowser/#/R-SCE-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1675810 https://reactome.org/PathwayBrowser/#/R-SCE-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1675813 https://reactome.org/PathwayBrowser/#/R-SCE-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1675883 https://reactome.org/PathwayBrowser/#/R-SCE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1675939 https://reactome.org/PathwayBrowser/#/R-SCE-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1675961 https://reactome.org/PathwayBrowser/#/R-SCE-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1675974 https://reactome.org/PathwayBrowser/#/R-SCE-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1675988 https://reactome.org/PathwayBrowser/#/R-SCE-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1675994 https://reactome.org/PathwayBrowser/#/R-SCE-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1676024 https://reactome.org/PathwayBrowser/#/R-SCE-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1676114 https://reactome.org/PathwayBrowser/#/R-SCE-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1676124 https://reactome.org/PathwayBrowser/#/R-SCE-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1676133 https://reactome.org/PathwayBrowser/#/R-SCE-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1676141 https://reactome.org/PathwayBrowser/#/R-SCE-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Saccharomyces cerevisiae 57880 R-SCE-1676185 https://reactome.org/PathwayBrowser/#/R-SCE-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Saccharomyces cerevisiae 57880 R-SCE-2046087 https://reactome.org/PathwayBrowser/#/R-SCE-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Saccharomyces cerevisiae 57880 R-SCE-5672012 https://reactome.org/PathwayBrowser/#/R-SCE-5672012 Beclin-1 complex phosphorylates PtdIns IEA Saccharomyces cerevisiae 57880 R-SCE-5679206 https://reactome.org/PathwayBrowser/#/R-SCE-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Saccharomyces cerevisiae 57880 R-SCE-6798174 https://reactome.org/PathwayBrowser/#/R-SCE-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Saccharomyces cerevisiae 57880 R-SCE-6809325 https://reactome.org/PathwayBrowser/#/R-SCE-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Saccharomyces cerevisiae 57880 R-SCE-6809720 https://reactome.org/PathwayBrowser/#/R-SCE-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Saccharomyces cerevisiae 57880 R-SCE-6809777 https://reactome.org/PathwayBrowser/#/R-SCE-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Saccharomyces cerevisiae 57880 R-SCE-8869241 https://reactome.org/PathwayBrowser/#/R-SCE-8869241 PITPNM1,2,3 exchange PI for PA IEA Saccharomyces cerevisiae 57880 R-SCE-8940388 https://reactome.org/PathwayBrowser/#/R-SCE-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Saccharomyces cerevisiae 57880 R-SCE-9794120 https://reactome.org/PathwayBrowser/#/R-SCE-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Saccharomyces cerevisiae 57880 R-SCE-9794572 https://reactome.org/PathwayBrowser/#/R-SCE-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Saccharomyces cerevisiae 57880 R-SPO-1482598 https://reactome.org/PathwayBrowser/#/R-SPO-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Schizosaccharomyces pombe 57880 R-SPO-1482626 https://reactome.org/PathwayBrowser/#/R-SPO-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Schizosaccharomyces pombe 57880 R-SPO-1482825 https://reactome.org/PathwayBrowser/#/R-SPO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Schizosaccharomyces pombe 57880 R-SPO-1482868 https://reactome.org/PathwayBrowser/#/R-SPO-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Schizosaccharomyces pombe 57880 R-SPO-1482932 https://reactome.org/PathwayBrowser/#/R-SPO-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Schizosaccharomyces pombe 57880 R-SPO-1482976 https://reactome.org/PathwayBrowser/#/R-SPO-1482976 CDP-DAG is converted to PI by CDIPT IEA Schizosaccharomyces pombe 57880 R-SPO-1675780 https://reactome.org/PathwayBrowser/#/R-SPO-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1675795 https://reactome.org/PathwayBrowser/#/R-SPO-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1675810 https://reactome.org/PathwayBrowser/#/R-SPO-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1675813 https://reactome.org/PathwayBrowser/#/R-SPO-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1675883 https://reactome.org/PathwayBrowser/#/R-SPO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1675939 https://reactome.org/PathwayBrowser/#/R-SPO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1675961 https://reactome.org/PathwayBrowser/#/R-SPO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1675974 https://reactome.org/PathwayBrowser/#/R-SPO-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1675988 https://reactome.org/PathwayBrowser/#/R-SPO-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1675994 https://reactome.org/PathwayBrowser/#/R-SPO-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1676024 https://reactome.org/PathwayBrowser/#/R-SPO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1676114 https://reactome.org/PathwayBrowser/#/R-SPO-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1676124 https://reactome.org/PathwayBrowser/#/R-SPO-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1676133 https://reactome.org/PathwayBrowser/#/R-SPO-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1676141 https://reactome.org/PathwayBrowser/#/R-SPO-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Schizosaccharomyces pombe 57880 R-SPO-1676185 https://reactome.org/PathwayBrowser/#/R-SPO-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Schizosaccharomyces pombe 57880 R-SPO-5672012 https://reactome.org/PathwayBrowser/#/R-SPO-5672012 Beclin-1 complex phosphorylates PtdIns IEA Schizosaccharomyces pombe 57880 R-SPO-5679206 https://reactome.org/PathwayBrowser/#/R-SPO-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Schizosaccharomyces pombe 57880 R-SPO-6798174 https://reactome.org/PathwayBrowser/#/R-SPO-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Schizosaccharomyces pombe 57880 R-SPO-6809325 https://reactome.org/PathwayBrowser/#/R-SPO-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Schizosaccharomyces pombe 57880 R-SPO-6809720 https://reactome.org/PathwayBrowser/#/R-SPO-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Schizosaccharomyces pombe 57880 R-SPO-6809777 https://reactome.org/PathwayBrowser/#/R-SPO-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Schizosaccharomyces pombe 57880 R-SPO-8869241 https://reactome.org/PathwayBrowser/#/R-SPO-8869241 PITPNM1,2,3 exchange PI for PA IEA Schizosaccharomyces pombe 57880 R-SSC-1482598 https://reactome.org/PathwayBrowser/#/R-SSC-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Sus scrofa 57880 R-SSC-1482626 https://reactome.org/PathwayBrowser/#/R-SSC-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Sus scrofa 57880 R-SSC-1482825 https://reactome.org/PathwayBrowser/#/R-SSC-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Sus scrofa 57880 R-SSC-1482868 https://reactome.org/PathwayBrowser/#/R-SSC-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Sus scrofa 57880 R-SSC-1482932 https://reactome.org/PathwayBrowser/#/R-SSC-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Sus scrofa 57880 R-SSC-1482976 https://reactome.org/PathwayBrowser/#/R-SSC-1482976 CDP-DAG is converted to PI by CDIPT IEA Sus scrofa 57880 R-SSC-1483087 https://reactome.org/PathwayBrowser/#/R-SSC-1483087 PI is exchanged with PC by PITPNB IEA Sus scrofa 57880 R-SSC-1483219 https://reactome.org/PathwayBrowser/#/R-SSC-1483219 PC is exchanged with PI by PITPNB IEA Sus scrofa 57880 R-SSC-1483229 https://reactome.org/PathwayBrowser/#/R-SSC-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Sus scrofa 57880 R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa 57880 R-SSC-162730 https://reactome.org/PathwayBrowser/#/R-SSC-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Sus scrofa 57880 R-SSC-1675780 https://reactome.org/PathwayBrowser/#/R-SSC-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Sus scrofa 57880 R-SSC-1675795 https://reactome.org/PathwayBrowser/#/R-SSC-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Sus scrofa 57880 R-SSC-1675810 https://reactome.org/PathwayBrowser/#/R-SSC-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Sus scrofa 57880 R-SSC-1675813 https://reactome.org/PathwayBrowser/#/R-SSC-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Sus scrofa 57880 R-SSC-1675883 https://reactome.org/PathwayBrowser/#/R-SSC-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Sus scrofa 57880 R-SSC-1675939 https://reactome.org/PathwayBrowser/#/R-SSC-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Sus scrofa 57880 R-SSC-1675961 https://reactome.org/PathwayBrowser/#/R-SSC-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Sus scrofa 57880 R-SSC-1675974 https://reactome.org/PathwayBrowser/#/R-SSC-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Sus scrofa 57880 R-SSC-1675988 https://reactome.org/PathwayBrowser/#/R-SSC-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Sus scrofa 57880 R-SSC-1675994 https://reactome.org/PathwayBrowser/#/R-SSC-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Sus scrofa 57880 R-SSC-1676024 https://reactome.org/PathwayBrowser/#/R-SSC-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Sus scrofa 57880 R-SSC-1676114 https://reactome.org/PathwayBrowser/#/R-SSC-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Sus scrofa 57880 R-SSC-1676124 https://reactome.org/PathwayBrowser/#/R-SSC-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Sus scrofa 57880 R-SSC-1676133 https://reactome.org/PathwayBrowser/#/R-SSC-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Sus scrofa 57880 R-SSC-1676141 https://reactome.org/PathwayBrowser/#/R-SSC-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Sus scrofa 57880 R-SSC-1676185 https://reactome.org/PathwayBrowser/#/R-SSC-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Sus scrofa 57880 R-SSC-2046087 https://reactome.org/PathwayBrowser/#/R-SSC-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Sus scrofa 57880 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 57880 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 57880 R-SSC-5672012 https://reactome.org/PathwayBrowser/#/R-SSC-5672012 Beclin-1 complex phosphorylates PtdIns IEA Sus scrofa 57880 R-SSC-5679206 https://reactome.org/PathwayBrowser/#/R-SSC-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Sus scrofa 57880 R-SSC-6798174 https://reactome.org/PathwayBrowser/#/R-SSC-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Sus scrofa 57880 R-SSC-6809325 https://reactome.org/PathwayBrowser/#/R-SSC-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Sus scrofa 57880 R-SSC-6809720 https://reactome.org/PathwayBrowser/#/R-SSC-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Sus scrofa 57880 R-SSC-6809777 https://reactome.org/PathwayBrowser/#/R-SSC-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Sus scrofa 57880 R-SSC-8869241 https://reactome.org/PathwayBrowser/#/R-SSC-8869241 PITPNM1,2,3 exchange PI for PA IEA Sus scrofa 57880 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa 57880 R-SSC-9794120 https://reactome.org/PathwayBrowser/#/R-SSC-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Sus scrofa 57880 R-SSC-9794572 https://reactome.org/PathwayBrowser/#/R-SSC-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Sus scrofa 57880 R-XTR-1482598 https://reactome.org/PathwayBrowser/#/R-XTR-1482598 1-acyl LPI is acylated to PI by MBOAT7 IEA Xenopus tropicalis 57880 R-XTR-1482626 https://reactome.org/PathwayBrowser/#/R-XTR-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Xenopus tropicalis 57880 R-XTR-1482825 https://reactome.org/PathwayBrowser/#/R-XTR-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Xenopus tropicalis 57880 R-XTR-1482868 https://reactome.org/PathwayBrowser/#/R-XTR-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Xenopus tropicalis 57880 R-XTR-1482976 https://reactome.org/PathwayBrowser/#/R-XTR-1482976 CDP-DAG is converted to PI by CDIPT IEA Xenopus tropicalis 57880 R-XTR-1483087 https://reactome.org/PathwayBrowser/#/R-XTR-1483087 PI is exchanged with PC by PITPNB IEA Xenopus tropicalis 57880 R-XTR-1483219 https://reactome.org/PathwayBrowser/#/R-XTR-1483219 PC is exchanged with PI by PITPNB IEA Xenopus tropicalis 57880 R-XTR-1483229 https://reactome.org/PathwayBrowser/#/R-XTR-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Xenopus tropicalis 57880 R-XTR-1602377 https://reactome.org/PathwayBrowser/#/R-XTR-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Xenopus tropicalis 57880 R-XTR-162730 https://reactome.org/PathwayBrowser/#/R-XTR-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Xenopus tropicalis 57880 R-XTR-1675780 https://reactome.org/PathwayBrowser/#/R-XTR-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Xenopus tropicalis 57880 R-XTR-1675795 https://reactome.org/PathwayBrowser/#/R-XTR-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Xenopus tropicalis 57880 R-XTR-1675813 https://reactome.org/PathwayBrowser/#/R-XTR-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Xenopus tropicalis 57880 R-XTR-1675883 https://reactome.org/PathwayBrowser/#/R-XTR-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Xenopus tropicalis 57880 R-XTR-1675939 https://reactome.org/PathwayBrowser/#/R-XTR-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Xenopus tropicalis 57880 R-XTR-1675961 https://reactome.org/PathwayBrowser/#/R-XTR-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Xenopus tropicalis 57880 R-XTR-1675974 https://reactome.org/PathwayBrowser/#/R-XTR-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Xenopus tropicalis 57880 R-XTR-1675988 https://reactome.org/PathwayBrowser/#/R-XTR-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Xenopus tropicalis 57880 R-XTR-1675994 https://reactome.org/PathwayBrowser/#/R-XTR-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Xenopus tropicalis 57880 R-XTR-1676024 https://reactome.org/PathwayBrowser/#/R-XTR-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Xenopus tropicalis 57880 R-XTR-1676141 https://reactome.org/PathwayBrowser/#/R-XTR-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Xenopus tropicalis 57880 R-XTR-1676185 https://reactome.org/PathwayBrowser/#/R-XTR-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Xenopus tropicalis 57880 R-XTR-2046087 https://reactome.org/PathwayBrowser/#/R-XTR-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Xenopus tropicalis 57880 R-XTR-5672012 https://reactome.org/PathwayBrowser/#/R-XTR-5672012 Beclin-1 complex phosphorylates PtdIns IEA Xenopus tropicalis 57880 R-XTR-5679206 https://reactome.org/PathwayBrowser/#/R-XTR-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Xenopus tropicalis 57880 R-XTR-6809720 https://reactome.org/PathwayBrowser/#/R-XTR-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Xenopus tropicalis 57880 R-XTR-9794120 https://reactome.org/PathwayBrowser/#/R-XTR-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Xenopus tropicalis 57880 R-XTR-9794572 https://reactome.org/PathwayBrowser/#/R-XTR-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Xenopus tropicalis 57895 R-BTA-1855153 https://reactome.org/PathwayBrowser/#/R-BTA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Bos taurus 57895 R-BTA-1855172 https://reactome.org/PathwayBrowser/#/R-BTA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Bos taurus 57895 R-BTA-1855200 https://reactome.org/PathwayBrowser/#/R-BTA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Bos taurus 57895 R-BTA-1855205 https://reactome.org/PathwayBrowser/#/R-BTA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Bos taurus 57895 R-BTA-1855206 https://reactome.org/PathwayBrowser/#/R-BTA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Bos taurus 57895 R-BTA-1855213 https://reactome.org/PathwayBrowser/#/R-BTA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Bos taurus 57895 R-BTA-1855218 https://reactome.org/PathwayBrowser/#/R-BTA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Bos taurus 57895 R-BTA-1855233 https://reactome.org/PathwayBrowser/#/R-BTA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Bos taurus 57895 R-BTA-994140 https://reactome.org/PathwayBrowser/#/R-BTA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Bos taurus 57895 R-CEL-1855153 https://reactome.org/PathwayBrowser/#/R-CEL-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Caenorhabditis elegans 57895 R-CEL-1855205 https://reactome.org/PathwayBrowser/#/R-CEL-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Caenorhabditis elegans 57895 R-CEL-1855206 https://reactome.org/PathwayBrowser/#/R-CEL-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Caenorhabditis elegans 57895 R-CEL-1855213 https://reactome.org/PathwayBrowser/#/R-CEL-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Caenorhabditis elegans 57895 R-CEL-1855218 https://reactome.org/PathwayBrowser/#/R-CEL-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Caenorhabditis elegans 57895 R-CEL-1855233 https://reactome.org/PathwayBrowser/#/R-CEL-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Caenorhabditis elegans 57895 R-CFA-1855153 https://reactome.org/PathwayBrowser/#/R-CFA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Canis familiaris 57895 R-CFA-1855172 https://reactome.org/PathwayBrowser/#/R-CFA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Canis familiaris 57895 R-CFA-1855200 https://reactome.org/PathwayBrowser/#/R-CFA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Canis familiaris 57895 R-CFA-1855205 https://reactome.org/PathwayBrowser/#/R-CFA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Canis familiaris 57895 R-CFA-1855206 https://reactome.org/PathwayBrowser/#/R-CFA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Canis familiaris 57895 R-CFA-1855213 https://reactome.org/PathwayBrowser/#/R-CFA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Canis familiaris 57895 R-CFA-1855218 https://reactome.org/PathwayBrowser/#/R-CFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Canis familiaris 57895 R-CFA-1855233 https://reactome.org/PathwayBrowser/#/R-CFA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Canis familiaris 57895 R-CFA-994140 https://reactome.org/PathwayBrowser/#/R-CFA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Canis familiaris 57895 R-DDI-1855153 https://reactome.org/PathwayBrowser/#/R-DDI-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Dictyostelium discoideum 57895 R-DDI-1855172 https://reactome.org/PathwayBrowser/#/R-DDI-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 57895 R-DDI-1855200 https://reactome.org/PathwayBrowser/#/R-DDI-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 57895 R-DDI-1855205 https://reactome.org/PathwayBrowser/#/R-DDI-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Dictyostelium discoideum 57895 R-DDI-1855206 https://reactome.org/PathwayBrowser/#/R-DDI-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Dictyostelium discoideum 57895 R-DDI-1855213 https://reactome.org/PathwayBrowser/#/R-DDI-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Dictyostelium discoideum 57895 R-DDI-1855218 https://reactome.org/PathwayBrowser/#/R-DDI-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Dictyostelium discoideum 57895 R-DDI-1855233 https://reactome.org/PathwayBrowser/#/R-DDI-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Dictyostelium discoideum 57895 R-DDI-994140 https://reactome.org/PathwayBrowser/#/R-DDI-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Dictyostelium discoideum 57895 R-DME-1855153 https://reactome.org/PathwayBrowser/#/R-DME-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Drosophila melanogaster 57895 R-DME-1855205 https://reactome.org/PathwayBrowser/#/R-DME-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Drosophila melanogaster 57895 R-DME-1855206 https://reactome.org/PathwayBrowser/#/R-DME-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Drosophila melanogaster 57895 R-DME-1855213 https://reactome.org/PathwayBrowser/#/R-DME-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Drosophila melanogaster 57895 R-DME-1855218 https://reactome.org/PathwayBrowser/#/R-DME-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Drosophila melanogaster 57895 R-DME-1855233 https://reactome.org/PathwayBrowser/#/R-DME-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Drosophila melanogaster 57895 R-DRE-1855172 https://reactome.org/PathwayBrowser/#/R-DRE-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Danio rerio 57895 R-DRE-1855200 https://reactome.org/PathwayBrowser/#/R-DRE-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Danio rerio 57895 R-DRE-1855205 https://reactome.org/PathwayBrowser/#/R-DRE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Danio rerio 57895 R-DRE-1855206 https://reactome.org/PathwayBrowser/#/R-DRE-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Danio rerio 57895 R-DRE-1855218 https://reactome.org/PathwayBrowser/#/R-DRE-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Danio rerio 57895 R-DRE-1855233 https://reactome.org/PathwayBrowser/#/R-DRE-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Danio rerio 57895 R-DRE-994140 https://reactome.org/PathwayBrowser/#/R-DRE-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Danio rerio 57895 R-GGA-1855153 https://reactome.org/PathwayBrowser/#/R-GGA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Gallus gallus 57895 R-GGA-1855172 https://reactome.org/PathwayBrowser/#/R-GGA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Gallus gallus 57895 R-GGA-1855200 https://reactome.org/PathwayBrowser/#/R-GGA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Gallus gallus 57895 R-GGA-1855205 https://reactome.org/PathwayBrowser/#/R-GGA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Gallus gallus 57895 R-GGA-1855206 https://reactome.org/PathwayBrowser/#/R-GGA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Gallus gallus 57895 R-GGA-1855213 https://reactome.org/PathwayBrowser/#/R-GGA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Gallus gallus 57895 R-GGA-1855218 https://reactome.org/PathwayBrowser/#/R-GGA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Gallus gallus 57895 R-GGA-1855233 https://reactome.org/PathwayBrowser/#/R-GGA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Gallus gallus 57895 R-GGA-994140 https://reactome.org/PathwayBrowser/#/R-GGA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Gallus gallus 57895 R-HSA-1855153 https://reactome.org/PathwayBrowser/#/R-HSA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol TAS Homo sapiens 57895 R-HSA-1855168 https://reactome.org/PathwayBrowser/#/R-HSA-1855168 I(1,3,4,5)P4 transports from the cytosol to the nucleus TAS Homo sapiens 57895 R-HSA-1855172 https://reactome.org/PathwayBrowser/#/R-HSA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol TAS Homo sapiens 57895 R-HSA-1855186 https://reactome.org/PathwayBrowser/#/R-HSA-1855186 I(1,3,4,5)P4 transports from the cytosol to the ER lumen TAS Homo sapiens 57895 R-HSA-1855200 https://reactome.org/PathwayBrowser/#/R-HSA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen TAS Homo sapiens 57895 R-HSA-1855205 https://reactome.org/PathwayBrowser/#/R-HSA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol TAS Homo sapiens 57895 R-HSA-1855206 https://reactome.org/PathwayBrowser/#/R-HSA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus TAS Homo sapiens 57895 R-HSA-1855213 https://reactome.org/PathwayBrowser/#/R-HSA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane TAS Homo sapiens 57895 R-HSA-1855218 https://reactome.org/PathwayBrowser/#/R-HSA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol TAS Homo sapiens 57895 R-HSA-1855233 https://reactome.org/PathwayBrowser/#/R-HSA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus TAS Homo sapiens 57895 R-HSA-994140 https://reactome.org/PathwayBrowser/#/R-HSA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 TAS Homo sapiens 57895 R-MMU-1855153 https://reactome.org/PathwayBrowser/#/R-MMU-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Mus musculus 57895 R-MMU-1855172 https://reactome.org/PathwayBrowser/#/R-MMU-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Mus musculus 57895 R-MMU-1855200 https://reactome.org/PathwayBrowser/#/R-MMU-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Mus musculus 57895 R-MMU-1855205 https://reactome.org/PathwayBrowser/#/R-MMU-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Mus musculus 57895 R-MMU-1855206 https://reactome.org/PathwayBrowser/#/R-MMU-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Mus musculus 57895 R-MMU-1855213 https://reactome.org/PathwayBrowser/#/R-MMU-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Mus musculus 57895 R-MMU-1855218 https://reactome.org/PathwayBrowser/#/R-MMU-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Mus musculus 57895 R-MMU-1855233 https://reactome.org/PathwayBrowser/#/R-MMU-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Mus musculus 57895 R-MMU-994140 https://reactome.org/PathwayBrowser/#/R-MMU-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Mus musculus 57895 R-PFA-1855153 https://reactome.org/PathwayBrowser/#/R-PFA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Plasmodium falciparum 57895 R-PFA-1855206 https://reactome.org/PathwayBrowser/#/R-PFA-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Plasmodium falciparum 57895 R-PFA-1855213 https://reactome.org/PathwayBrowser/#/R-PFA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Plasmodium falciparum 57895 R-PFA-1855218 https://reactome.org/PathwayBrowser/#/R-PFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Plasmodium falciparum 57895 R-PFA-1855233 https://reactome.org/PathwayBrowser/#/R-PFA-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Plasmodium falciparum 57895 R-RNO-1855153 https://reactome.org/PathwayBrowser/#/R-RNO-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Rattus norvegicus 57895 R-RNO-1855172 https://reactome.org/PathwayBrowser/#/R-RNO-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 57895 R-RNO-1855200 https://reactome.org/PathwayBrowser/#/R-RNO-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Rattus norvegicus 57895 R-RNO-1855205 https://reactome.org/PathwayBrowser/#/R-RNO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Rattus norvegicus 57895 R-RNO-1855206 https://reactome.org/PathwayBrowser/#/R-RNO-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Rattus norvegicus 57895 R-RNO-1855213 https://reactome.org/PathwayBrowser/#/R-RNO-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Rattus norvegicus 57895 R-RNO-1855218 https://reactome.org/PathwayBrowser/#/R-RNO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Rattus norvegicus 57895 R-RNO-1855233 https://reactome.org/PathwayBrowser/#/R-RNO-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Rattus norvegicus 57895 R-RNO-994140 https://reactome.org/PathwayBrowser/#/R-RNO-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Rattus norvegicus 57895 R-SCE-1855205 https://reactome.org/PathwayBrowser/#/R-SCE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Saccharomyces cerevisiae 57895 R-SCE-1855218 https://reactome.org/PathwayBrowser/#/R-SCE-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Saccharomyces cerevisiae 57895 R-SPO-1855205 https://reactome.org/PathwayBrowser/#/R-SPO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Schizosaccharomyces pombe 57895 R-SPO-1855213 https://reactome.org/PathwayBrowser/#/R-SPO-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Schizosaccharomyces pombe 57895 R-SPO-1855218 https://reactome.org/PathwayBrowser/#/R-SPO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Schizosaccharomyces pombe 57895 R-SSC-1855153 https://reactome.org/PathwayBrowser/#/R-SSC-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Sus scrofa 57895 R-SSC-1855172 https://reactome.org/PathwayBrowser/#/R-SSC-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Sus scrofa 57895 R-SSC-1855200 https://reactome.org/PathwayBrowser/#/R-SSC-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Sus scrofa 57895 R-SSC-1855205 https://reactome.org/PathwayBrowser/#/R-SSC-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Sus scrofa 57895 R-SSC-1855213 https://reactome.org/PathwayBrowser/#/R-SSC-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Sus scrofa 57895 R-SSC-1855218 https://reactome.org/PathwayBrowser/#/R-SSC-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Sus scrofa 57895 R-SSC-994140 https://reactome.org/PathwayBrowser/#/R-SSC-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Sus scrofa 57895 R-XTR-1855172 https://reactome.org/PathwayBrowser/#/R-XTR-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 57895 R-XTR-1855200 https://reactome.org/PathwayBrowser/#/R-XTR-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Xenopus tropicalis 57895 R-XTR-1855205 https://reactome.org/PathwayBrowser/#/R-XTR-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Xenopus tropicalis 57895 R-XTR-1855206 https://reactome.org/PathwayBrowser/#/R-XTR-1855206 I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus IEA Xenopus tropicalis 57895 R-XTR-1855213 https://reactome.org/PathwayBrowser/#/R-XTR-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Xenopus tropicalis 57895 R-XTR-1855218 https://reactome.org/PathwayBrowser/#/R-XTR-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Xenopus tropicalis 57895 R-XTR-1855233 https://reactome.org/PathwayBrowser/#/R-XTR-1855233 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus IEA Xenopus tropicalis 57895 R-XTR-994140 https://reactome.org/PathwayBrowser/#/R-XTR-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Xenopus tropicalis 57905 R-BTA-176631 https://reactome.org/PathwayBrowser/#/R-BTA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Bos taurus 57905 R-BTA-561059 https://reactome.org/PathwayBrowser/#/R-BTA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Bos taurus 57905 R-BTA-879562 https://reactome.org/PathwayBrowser/#/R-BTA-879562 SLCO2B1 has a narrow substrate specificity IEA Bos taurus 57905 R-CEL-561059 https://reactome.org/PathwayBrowser/#/R-CEL-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Caenorhabditis elegans 57905 R-CEL-879562 https://reactome.org/PathwayBrowser/#/R-CEL-879562 SLCO2B1 has a narrow substrate specificity IEA Caenorhabditis elegans 57905 R-CFA-176631 https://reactome.org/PathwayBrowser/#/R-CFA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Canis familiaris 57905 R-CFA-561059 https://reactome.org/PathwayBrowser/#/R-CFA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Canis familiaris 57905 R-CFA-879562 https://reactome.org/PathwayBrowser/#/R-CFA-879562 SLCO2B1 has a narrow substrate specificity IEA Canis familiaris 57905 R-DME-176631 https://reactome.org/PathwayBrowser/#/R-DME-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Drosophila melanogaster 57905 R-DME-561059 https://reactome.org/PathwayBrowser/#/R-DME-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Drosophila melanogaster 57905 R-DME-879562 https://reactome.org/PathwayBrowser/#/R-DME-879562 SLCO2B1 has a narrow substrate specificity IEA Drosophila melanogaster 57905 R-DRE-176631 https://reactome.org/PathwayBrowser/#/R-DRE-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Danio rerio 57905 R-DRE-561059 https://reactome.org/PathwayBrowser/#/R-DRE-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Danio rerio 57905 R-DRE-879562 https://reactome.org/PathwayBrowser/#/R-DRE-879562 SLCO2B1 has a narrow substrate specificity IEA Danio rerio 57905 R-GGA-176631 https://reactome.org/PathwayBrowser/#/R-GGA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Gallus gallus 57905 R-GGA-561059 https://reactome.org/PathwayBrowser/#/R-GGA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Gallus gallus 57905 R-GGA-879562 https://reactome.org/PathwayBrowser/#/R-GGA-879562 SLCO2B1 has a narrow substrate specificity IEA Gallus gallus 57905 R-HSA-176631 https://reactome.org/PathwayBrowser/#/R-HSA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP TAS Homo sapiens 57905 R-HSA-561059 https://reactome.org/PathwayBrowser/#/R-HSA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates TAS Homo sapiens 57905 R-HSA-879562 https://reactome.org/PathwayBrowser/#/R-HSA-879562 SLCO2B1 has a narrow substrate specificity TAS Homo sapiens 57905 R-MMU-176631 https://reactome.org/PathwayBrowser/#/R-MMU-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Mus musculus 57905 R-MMU-561059 https://reactome.org/PathwayBrowser/#/R-MMU-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Mus musculus 57905 R-MMU-879562 https://reactome.org/PathwayBrowser/#/R-MMU-879562 SLCO2B1 has a narrow substrate specificity IEA Mus musculus 57905 R-RNO-176631 https://reactome.org/PathwayBrowser/#/R-RNO-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Rattus norvegicus 57905 R-RNO-561059 https://reactome.org/PathwayBrowser/#/R-RNO-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Rattus norvegicus 57905 R-RNO-879562 https://reactome.org/PathwayBrowser/#/R-RNO-879562 SLCO2B1 has a narrow substrate specificity IEA Rattus norvegicus 57905 R-SSC-176631 https://reactome.org/PathwayBrowser/#/R-SSC-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Sus scrofa 57905 R-SSC-561059 https://reactome.org/PathwayBrowser/#/R-SSC-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Sus scrofa 57905 R-SSC-879562 https://reactome.org/PathwayBrowser/#/R-SSC-879562 SLCO2B1 has a narrow substrate specificity IEA Sus scrofa 57905 R-XTR-176631 https://reactome.org/PathwayBrowser/#/R-XTR-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Xenopus tropicalis 57905 R-XTR-879562 https://reactome.org/PathwayBrowser/#/R-XTR-879562 SLCO2B1 has a narrow substrate specificity IEA Xenopus tropicalis 57912 R-BTA-198563 https://reactome.org/PathwayBrowser/#/R-BTA-198563 IDO1 dioxygenates L-Trp to NFK IEA Bos taurus 57912 R-BTA-209828 https://reactome.org/PathwayBrowser/#/R-BTA-209828 Tryptophan is hydroxylated IEA Bos taurus 57912 R-BTA-352158 https://reactome.org/PathwayBrowser/#/R-BTA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Bos taurus 57912 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 57912 R-BTA-352232 https://reactome.org/PathwayBrowser/#/R-BTA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Bos taurus 57912 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 57912 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 57912 R-BTA-71188 https://reactome.org/PathwayBrowser/#/R-BTA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Bos taurus 57912 R-BTA-8870352 https://reactome.org/PathwayBrowser/#/R-BTA-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Bos taurus 57912 R-BTA-888614 https://reactome.org/PathwayBrowser/#/R-BTA-888614 IDO2 dioxygenates L-Trp to NFK IEA Bos taurus 57912 R-CEL-209828 https://reactome.org/PathwayBrowser/#/R-CEL-209828 Tryptophan is hydroxylated IEA Caenorhabditis elegans 57912 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 57912 R-CEL-71188 https://reactome.org/PathwayBrowser/#/R-CEL-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Caenorhabditis elegans 57912 R-CEL-8870352 https://reactome.org/PathwayBrowser/#/R-CEL-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Caenorhabditis elegans 57912 R-CFA-198563 https://reactome.org/PathwayBrowser/#/R-CFA-198563 IDO1 dioxygenates L-Trp to NFK IEA Canis familiaris 57912 R-CFA-209828 https://reactome.org/PathwayBrowser/#/R-CFA-209828 Tryptophan is hydroxylated IEA Canis familiaris 57912 R-CFA-352158 https://reactome.org/PathwayBrowser/#/R-CFA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Canis familiaris 57912 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 57912 R-CFA-352232 https://reactome.org/PathwayBrowser/#/R-CFA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Canis familiaris 57912 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 57912 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 57912 R-CFA-71188 https://reactome.org/PathwayBrowser/#/R-CFA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Canis familiaris 57912 R-CFA-8870352 https://reactome.org/PathwayBrowser/#/R-CFA-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Canis familiaris 57912 R-CFA-888614 https://reactome.org/PathwayBrowser/#/R-CFA-888614 IDO2 dioxygenates L-Trp to NFK IEA Canis familiaris 57912 R-DDI-209828 https://reactome.org/PathwayBrowser/#/R-DDI-209828 Tryptophan is hydroxylated IEA Dictyostelium discoideum 57912 R-DDI-352158 https://reactome.org/PathwayBrowser/#/R-DDI-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Dictyostelium discoideum 57912 R-DDI-71188 https://reactome.org/PathwayBrowser/#/R-DDI-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Dictyostelium discoideum 57912 R-DDI-8870352 https://reactome.org/PathwayBrowser/#/R-DDI-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Dictyostelium discoideum 57912 R-DME-209828 https://reactome.org/PathwayBrowser/#/R-DME-209828 Tryptophan is hydroxylated IEA Drosophila melanogaster 57912 R-DME-352158 https://reactome.org/PathwayBrowser/#/R-DME-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Drosophila melanogaster 57912 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57912 R-DME-352232 https://reactome.org/PathwayBrowser/#/R-DME-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Drosophila melanogaster 57912 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57912 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57912 R-DME-71188 https://reactome.org/PathwayBrowser/#/R-DME-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Drosophila melanogaster 57912 R-DME-8870352 https://reactome.org/PathwayBrowser/#/R-DME-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Drosophila melanogaster 57912 R-DRE-209828 https://reactome.org/PathwayBrowser/#/R-DRE-209828 Tryptophan is hydroxylated IEA Danio rerio 57912 R-DRE-352158 https://reactome.org/PathwayBrowser/#/R-DRE-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Danio rerio 57912 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 57912 R-DRE-71188 https://reactome.org/PathwayBrowser/#/R-DRE-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Danio rerio 57912 R-DRE-8870352 https://reactome.org/PathwayBrowser/#/R-DRE-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Danio rerio 57912 R-DRE-888614 https://reactome.org/PathwayBrowser/#/R-DRE-888614 IDO2 dioxygenates L-Trp to NFK IEA Danio rerio 57912 R-GGA-209828 https://reactome.org/PathwayBrowser/#/R-GGA-209828 Tryptophan is hydroxylated IEA Gallus gallus 57912 R-GGA-352158 https://reactome.org/PathwayBrowser/#/R-GGA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Gallus gallus 57912 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 57912 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 57912 R-GGA-71188 https://reactome.org/PathwayBrowser/#/R-GGA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Gallus gallus 57912 R-GGA-8870352 https://reactome.org/PathwayBrowser/#/R-GGA-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Gallus gallus 57912 R-GGA-888614 https://reactome.org/PathwayBrowser/#/R-GGA-888614 IDO2 dioxygenates L-Trp to NFK IEA Gallus gallus 57912 R-HSA-198563 https://reactome.org/PathwayBrowser/#/R-HSA-198563 IDO1 dioxygenates L-Trp to NFK TAS Homo sapiens 57912 R-HSA-209828 https://reactome.org/PathwayBrowser/#/R-HSA-209828 Tryptophan is hydroxylated TAS Homo sapiens 57912 R-HSA-352158 https://reactome.org/PathwayBrowser/#/R-HSA-352158 SLC16A10-mediated uptake of aromatic amino acids TAS Homo sapiens 57912 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 57912 R-HSA-352232 https://reactome.org/PathwayBrowser/#/R-HSA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol TAS Homo sapiens 57912 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57912 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57912 R-HSA-379977 https://reactome.org/PathwayBrowser/#/R-HSA-379977 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 57912 R-HSA-380222 https://reactome.org/PathwayBrowser/#/R-HSA-380222 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate TAS Homo sapiens 57912 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57912 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57912 R-HSA-71188 https://reactome.org/PathwayBrowser/#/R-HSA-71188 TDO tetramer dioxygenates L-Trp to NFK TAS Homo sapiens 57912 R-HSA-8870352 https://reactome.org/PathwayBrowser/#/R-HSA-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol TAS Homo sapiens 57912 R-HSA-888614 https://reactome.org/PathwayBrowser/#/R-HSA-888614 IDO2 dioxygenates L-Trp to NFK TAS Homo sapiens 57912 R-MMU-198563 https://reactome.org/PathwayBrowser/#/R-MMU-198563 IDO1 dioxygenates L-Trp to NFK IEA Mus musculus 57912 R-MMU-209828 https://reactome.org/PathwayBrowser/#/R-MMU-209828 Tryptophan is hydroxylated IEA Mus musculus 57912 R-MMU-352158 https://reactome.org/PathwayBrowser/#/R-MMU-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Mus musculus 57912 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 57912 R-MMU-352232 https://reactome.org/PathwayBrowser/#/R-MMU-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Mus musculus 57912 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 57912 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 57912 R-MMU-71188 https://reactome.org/PathwayBrowser/#/R-MMU-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Mus musculus 57912 R-MMU-8870352 https://reactome.org/PathwayBrowser/#/R-MMU-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Mus musculus 57912 R-MMU-888614 https://reactome.org/PathwayBrowser/#/R-MMU-888614 IDO2 dioxygenates L-Trp to NFK IEA Mus musculus 57912 R-PFA-352158 https://reactome.org/PathwayBrowser/#/R-PFA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Plasmodium falciparum 57912 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57912 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57912 R-RNO-198563 https://reactome.org/PathwayBrowser/#/R-RNO-198563 IDO1 dioxygenates L-Trp to NFK IEA Rattus norvegicus 57912 R-RNO-209828 https://reactome.org/PathwayBrowser/#/R-RNO-209828 Tryptophan is hydroxylated IEA Rattus norvegicus 57912 R-RNO-352158 https://reactome.org/PathwayBrowser/#/R-RNO-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Rattus norvegicus 57912 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 57912 R-RNO-352232 https://reactome.org/PathwayBrowser/#/R-RNO-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Rattus norvegicus 57912 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 57912 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 57912 R-RNO-71188 https://reactome.org/PathwayBrowser/#/R-RNO-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Rattus norvegicus 57912 R-RNO-8870352 https://reactome.org/PathwayBrowser/#/R-RNO-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Rattus norvegicus 57912 R-RNO-888614 https://reactome.org/PathwayBrowser/#/R-RNO-888614 IDO2 dioxygenates L-Trp to NFK IEA Rattus norvegicus 57912 R-SCE-198563 https://reactome.org/PathwayBrowser/#/R-SCE-198563 IDO1 dioxygenates L-Trp to NFK IEA Saccharomyces cerevisiae 57912 R-SCE-352158 https://reactome.org/PathwayBrowser/#/R-SCE-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Saccharomyces cerevisiae 57912 R-SCE-8870352 https://reactome.org/PathwayBrowser/#/R-SCE-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Saccharomyces cerevisiae 57912 R-SCE-888614 https://reactome.org/PathwayBrowser/#/R-SCE-888614 IDO2 dioxygenates L-Trp to NFK IEA Saccharomyces cerevisiae 57912 R-SSC-198563 https://reactome.org/PathwayBrowser/#/R-SSC-198563 IDO1 dioxygenates L-Trp to NFK IEA Sus scrofa 57912 R-SSC-209828 https://reactome.org/PathwayBrowser/#/R-SSC-209828 Tryptophan is hydroxylated IEA Sus scrofa 57912 R-SSC-352158 https://reactome.org/PathwayBrowser/#/R-SSC-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Sus scrofa 57912 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 57912 R-SSC-352232 https://reactome.org/PathwayBrowser/#/R-SSC-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Sus scrofa 57912 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 57912 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 57912 R-SSC-71188 https://reactome.org/PathwayBrowser/#/R-SSC-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Sus scrofa 57912 R-SSC-8870352 https://reactome.org/PathwayBrowser/#/R-SSC-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Sus scrofa 57912 R-SSC-888614 https://reactome.org/PathwayBrowser/#/R-SSC-888614 IDO2 dioxygenates L-Trp to NFK IEA Sus scrofa 57912 R-XTR-352158 https://reactome.org/PathwayBrowser/#/R-XTR-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Xenopus tropicalis 57912 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57912 R-XTR-352232 https://reactome.org/PathwayBrowser/#/R-XTR-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Xenopus tropicalis 57912 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57912 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57912 R-XTR-71188 https://reactome.org/PathwayBrowser/#/R-XTR-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Xenopus tropicalis 57912 R-XTR-8870352 https://reactome.org/PathwayBrowser/#/R-XTR-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol IEA Xenopus tropicalis 57912 R-XTR-888614 https://reactome.org/PathwayBrowser/#/R-XTR-888614 IDO2 dioxygenates L-Trp to NFK IEA Xenopus tropicalis 57916 R-SCE-2164816 https://reactome.org/PathwayBrowser/#/R-SCE-2164816 MHHB is decarboxylated to HMPhOH by MHHB decarboxylase TAS Saccharomyces cerevisiae 57923 R-BTA-1675836 https://reactome.org/PathwayBrowser/#/R-BTA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Bos taurus 57923 R-BTA-1676005 https://reactome.org/PathwayBrowser/#/R-BTA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Bos taurus 57923 R-BTA-1676020 https://reactome.org/PathwayBrowser/#/R-BTA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Bos taurus 57923 R-BTA-1676065 https://reactome.org/PathwayBrowser/#/R-BTA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Bos taurus 57923 R-BTA-1676105 https://reactome.org/PathwayBrowser/#/R-BTA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Bos taurus 57923 R-BTA-1676134 https://reactome.org/PathwayBrowser/#/R-BTA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Bos taurus 57923 R-BTA-1676174 https://reactome.org/PathwayBrowser/#/R-BTA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Bos taurus 57923 R-BTA-1676203 https://reactome.org/PathwayBrowser/#/R-BTA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Bos taurus 57923 R-BTA-5333658 https://reactome.org/PathwayBrowser/#/R-BTA-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Bos taurus 57923 R-BTA-5678490 https://reactome.org/PathwayBrowser/#/R-BTA-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Bos taurus 57923 R-BTA-5679255 https://reactome.org/PathwayBrowser/#/R-BTA-5679255 WIPI2 binds ATG12:ATG5:ATG16L IEA Bos taurus 57923 R-BTA-6809320 https://reactome.org/PathwayBrowser/#/R-BTA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Bos taurus 57923 R-BTA-6809778 https://reactome.org/PathwayBrowser/#/R-BTA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Bos taurus 57923 R-BTA-8849969 https://reactome.org/PathwayBrowser/#/R-BTA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Bos taurus 57923 R-CEL-1675836 https://reactome.org/PathwayBrowser/#/R-CEL-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Caenorhabditis elegans 57923 R-CEL-1676065 https://reactome.org/PathwayBrowser/#/R-CEL-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Caenorhabditis elegans 57923 R-CEL-1676105 https://reactome.org/PathwayBrowser/#/R-CEL-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Caenorhabditis elegans 57923 R-CEL-1676134 https://reactome.org/PathwayBrowser/#/R-CEL-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Caenorhabditis elegans 57923 R-CEL-1676203 https://reactome.org/PathwayBrowser/#/R-CEL-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Caenorhabditis elegans 57923 R-CEL-5333658 https://reactome.org/PathwayBrowser/#/R-CEL-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Caenorhabditis elegans 57923 R-CEL-5678490 https://reactome.org/PathwayBrowser/#/R-CEL-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Caenorhabditis elegans 57923 R-CEL-5679255 https://reactome.org/PathwayBrowser/#/R-CEL-5679255 WIPI2 binds ATG12:ATG5:ATG16L IEA Caenorhabditis elegans 57923 R-CEL-6809320 https://reactome.org/PathwayBrowser/#/R-CEL-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Caenorhabditis elegans 57923 R-CEL-6809778 https://reactome.org/PathwayBrowser/#/R-CEL-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Caenorhabditis elegans 57923 R-CEL-8849969 https://reactome.org/PathwayBrowser/#/R-CEL-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Caenorhabditis elegans 57923 R-CFA-1675836 https://reactome.org/PathwayBrowser/#/R-CFA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Canis familiaris 57923 R-CFA-1676005 https://reactome.org/PathwayBrowser/#/R-CFA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Canis familiaris 57923 R-CFA-1676020 https://reactome.org/PathwayBrowser/#/R-CFA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Canis familiaris 57923 R-CFA-1676065 https://reactome.org/PathwayBrowser/#/R-CFA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Canis familiaris 57923 R-CFA-1676105 https://reactome.org/PathwayBrowser/#/R-CFA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Canis familiaris 57923 R-CFA-1676134 https://reactome.org/PathwayBrowser/#/R-CFA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Canis familiaris 57923 R-CFA-1676174 https://reactome.org/PathwayBrowser/#/R-CFA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Canis familiaris 57923 R-CFA-1676203 https://reactome.org/PathwayBrowser/#/R-CFA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Canis familiaris 57923 R-CFA-5333658 https://reactome.org/PathwayBrowser/#/R-CFA-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Canis familiaris 57923 R-CFA-5678490 https://reactome.org/PathwayBrowser/#/R-CFA-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Canis familiaris 57923 R-CFA-5679255 https://reactome.org/PathwayBrowser/#/R-CFA-5679255 WIPI2 binds ATG12:ATG5:ATG16L IEA Canis familiaris 57923 R-CFA-6809320 https://reactome.org/PathwayBrowser/#/R-CFA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Canis familiaris 57923 R-CFA-6809778 https://reactome.org/PathwayBrowser/#/R-CFA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Canis familiaris 57923 R-CFA-8849969 https://reactome.org/PathwayBrowser/#/R-CFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Canis familiaris 57923 R-DDI-1675836 https://reactome.org/PathwayBrowser/#/R-DDI-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Dictyostelium discoideum 57923 R-DDI-1676065 https://reactome.org/PathwayBrowser/#/R-DDI-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Dictyostelium discoideum 57923 R-DDI-1676105 https://reactome.org/PathwayBrowser/#/R-DDI-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Dictyostelium discoideum 57923 R-DDI-1676134 https://reactome.org/PathwayBrowser/#/R-DDI-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Dictyostelium discoideum 57923 R-DDI-1676203 https://reactome.org/PathwayBrowser/#/R-DDI-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Dictyostelium discoideum 57923 R-DDI-5333658 https://reactome.org/PathwayBrowser/#/R-DDI-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Dictyostelium discoideum 57923 R-DDI-5678490 https://reactome.org/PathwayBrowser/#/R-DDI-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Dictyostelium discoideum 57923 R-DDI-5679255 https://reactome.org/PathwayBrowser/#/R-DDI-5679255 WIPI2 binds ATG12:ATG5:ATG16L IEA Dictyostelium discoideum 57923 R-DDI-6809320 https://reactome.org/PathwayBrowser/#/R-DDI-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Dictyostelium discoideum 57923 R-DDI-6809778 https://reactome.org/PathwayBrowser/#/R-DDI-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Dictyostelium discoideum 57923 R-DDI-8849969 https://reactome.org/PathwayBrowser/#/R-DDI-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Dictyostelium discoideum 57923 R-DME-1675836 https://reactome.org/PathwayBrowser/#/R-DME-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Drosophila melanogaster 57923 R-DME-1676065 https://reactome.org/PathwayBrowser/#/R-DME-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Drosophila melanogaster 57923 R-DME-1676105 https://reactome.org/PathwayBrowser/#/R-DME-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Drosophila melanogaster 57923 R-DME-1676134 https://reactome.org/PathwayBrowser/#/R-DME-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Drosophila melanogaster 57923 R-DME-1676203 https://reactome.org/PathwayBrowser/#/R-DME-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Drosophila melanogaster 57923 R-DME-5333658 https://reactome.org/PathwayBrowser/#/R-DME-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Drosophila melanogaster 57923 R-DME-5678490 https://reactome.org/PathwayBrowser/#/R-DME-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Drosophila melanogaster 57923 R-DME-5679255 https://reactome.org/PathwayBrowser/#/R-DME-5679255 WIPI2 binds ATG12:ATG5:ATG16L IEA Drosophila melanogaster 57923 R-DME-6809320 https://reactome.org/PathwayBrowser/#/R-DME-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Drosophila melanogaster 57923 R-DME-6809778 https://reactome.org/PathwayBrowser/#/R-DME-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Drosophila melanogaster 57923 R-DME-8849969 https://reactome.org/PathwayBrowser/#/R-DME-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Drosophila melanogaster 57923 R-DRE-1676065 https://reactome.org/PathwayBrowser/#/R-DRE-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Danio rerio 57923 R-DRE-1676105 https://reactome.org/PathwayBrowser/#/R-DRE-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Danio rerio 57923 R-DRE-1676134 https://reactome.org/PathwayBrowser/#/R-DRE-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Danio rerio 57923 R-DRE-1676203 https://reactome.org/PathwayBrowser/#/R-DRE-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Danio rerio 57923 R-DRE-6809320 https://reactome.org/PathwayBrowser/#/R-DRE-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Danio rerio 57923 R-DRE-8849969 https://reactome.org/PathwayBrowser/#/R-DRE-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Danio rerio 57923 R-GGA-1675836 https://reactome.org/PathwayBrowser/#/R-GGA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Gallus gallus 57923 R-GGA-1676005 https://reactome.org/PathwayBrowser/#/R-GGA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Gallus gallus 57923 R-GGA-1676020 https://reactome.org/PathwayBrowser/#/R-GGA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Gallus gallus 57923 R-GGA-1676065 https://reactome.org/PathwayBrowser/#/R-GGA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Gallus gallus 57923 R-GGA-1676105 https://reactome.org/PathwayBrowser/#/R-GGA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Gallus gallus 57923 R-GGA-1676134 https://reactome.org/PathwayBrowser/#/R-GGA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Gallus gallus 57923 R-GGA-1676174 https://reactome.org/PathwayBrowser/#/R-GGA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Gallus gallus 57923 R-GGA-1676203 https://reactome.org/PathwayBrowser/#/R-GGA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Gallus gallus 57923 R-GGA-5333658 https://reactome.org/PathwayBrowser/#/R-GGA-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Gallus gallus 57923 R-GGA-5678490 https://reactome.org/PathwayBrowser/#/R-GGA-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Gallus gallus 57923 R-GGA-5679255 https://reactome.org/PathwayBrowser/#/R-GGA-5679255 WIPI2 binds ATG12:ATG5:ATG16L IEA Gallus gallus 57923 R-GGA-6809320 https://reactome.org/PathwayBrowser/#/R-GGA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Gallus gallus 57923 R-GGA-6809778 https://reactome.org/PathwayBrowser/#/R-GGA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Gallus gallus 57923 R-GGA-8849969 https://reactome.org/PathwayBrowser/#/R-GGA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Gallus gallus 57923 R-HSA-1675836 https://reactome.org/PathwayBrowser/#/R-HSA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane TAS Homo sapiens 57923 R-HSA-1675896 https://reactome.org/PathwayBrowser/#/R-HSA-1675896 PI(3,5)P2 transports from the early endosome membrane to the Golgi membrane TAS Homo sapiens 57923 R-HSA-1675910 https://reactome.org/PathwayBrowser/#/R-HSA-1675910 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the late endosome membrane IEA Homo sapiens 57923 R-HSA-1675921 https://reactome.org/PathwayBrowser/#/R-HSA-1675921 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the Golgi membrane IEA Homo sapiens 57923 R-HSA-1676005 https://reactome.org/PathwayBrowser/#/R-HSA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane TAS Homo sapiens 57923 R-HSA-1676020 https://reactome.org/PathwayBrowser/#/R-HSA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane TAS Homo sapiens 57923 R-HSA-1676041 https://reactome.org/PathwayBrowser/#/R-HSA-1676041 Presence of PI(3,5)P2 stimulates the maturation of the early endosome into the late endosome TAS Homo sapiens 57923 R-HSA-1676065 https://reactome.org/PathwayBrowser/#/R-HSA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane TAS Homo sapiens 57923 R-HSA-1676105 https://reactome.org/PathwayBrowser/#/R-HSA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane TAS Homo sapiens 57923 R-HSA-1676134 https://reactome.org/PathwayBrowser/#/R-HSA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane TAS Homo sapiens 57923 R-HSA-1676161 https://reactome.org/PathwayBrowser/#/R-HSA-1676161 PI(3,5)P2 transports from the late endosome membrane to the Golgi membrane TAS Homo sapiens 57923 R-HSA-1676168 https://reactome.org/PathwayBrowser/#/R-HSA-1676168 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane IEA Homo sapiens 57923 R-HSA-1676174 https://reactome.org/PathwayBrowser/#/R-HSA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane TAS Homo sapiens 57923 R-HSA-1676203 https://reactome.org/PathwayBrowser/#/R-HSA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane TAS Homo sapiens 57923 R-HSA-5333658 https://reactome.org/PathwayBrowser/#/R-HSA-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 TAS Homo sapiens 57923 R-HSA-5678490 https://reactome.org/PathwayBrowser/#/R-HSA-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE TAS Homo sapiens 57923 R-HSA-5679255 https://reactome.org/PathwayBrowser/#/R-HSA-5679255 WIPI2 binds ATG12:ATG5:ATG16L TAS Homo sapiens 57923 R-HSA-6809320 https://reactome.org/PathwayBrowser/#/R-HSA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane TAS Homo sapiens 57923 R-HSA-6809778 https://reactome.org/PathwayBrowser/#/R-HSA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 TAS Homo sapiens 57923 R-HSA-6809944 https://reactome.org/PathwayBrowser/#/R-HSA-6809944 PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane IEA Homo sapiens 57923 R-HSA-8849969 https://reactome.org/PathwayBrowser/#/R-HSA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane TAS Homo sapiens 57923 R-MMU-1675836 https://reactome.org/PathwayBrowser/#/R-MMU-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Mus musculus 57923 R-MMU-1676005 https://reactome.org/PathwayBrowser/#/R-MMU-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Mus musculus 57923 R-MMU-1676020 https://reactome.org/PathwayBrowser/#/R-MMU-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Mus musculus 57923 R-MMU-1676065 https://reactome.org/PathwayBrowser/#/R-MMU-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Mus musculus 57923 R-MMU-1676105 https://reactome.org/PathwayBrowser/#/R-MMU-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Mus musculus 57923 R-MMU-1676134 https://reactome.org/PathwayBrowser/#/R-MMU-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Mus musculus 57923 R-MMU-1676174 https://reactome.org/PathwayBrowser/#/R-MMU-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Mus musculus 57923 R-MMU-1676203 https://reactome.org/PathwayBrowser/#/R-MMU-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Mus musculus 57923 R-MMU-5333658 https://reactome.org/PathwayBrowser/#/R-MMU-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Mus musculus 57923 R-MMU-5678490 https://reactome.org/PathwayBrowser/#/R-MMU-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Mus musculus 57923 R-MMU-5679255 https://reactome.org/PathwayBrowser/#/R-MMU-5679255 WIPI2 binds ATG12:ATG5:ATG16L IEA Mus musculus 57923 R-MMU-6809320 https://reactome.org/PathwayBrowser/#/R-MMU-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Mus musculus 57923 R-MMU-6809778 https://reactome.org/PathwayBrowser/#/R-MMU-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Mus musculus 57923 R-MMU-6809945 https://reactome.org/PathwayBrowser/#/R-MMU-6809945 PI(3,5)P2 is dephosphorylated to PI5P by the Mtmr2:Sbf2 tetramer at the plasma membrane TAS Mus musculus 57923 R-MMU-8849969 https://reactome.org/PathwayBrowser/#/R-MMU-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Mus musculus 57923 R-NUL-1675886 https://reactome.org/PathwayBrowser/#/R-NUL-1675886 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the early endosome membrane TAS Mus musculus 57923 R-NUL-1675925 https://reactome.org/PathwayBrowser/#/R-NUL-1675925 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the late endosome membrane TAS Mus musculus 57923 R-NUL-1675982 https://reactome.org/PathwayBrowser/#/R-NUL-1675982 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the Golgi membrane TAS Mus musculus 57923 R-PFA-1675836 https://reactome.org/PathwayBrowser/#/R-PFA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Plasmodium falciparum 57923 R-PFA-1676134 https://reactome.org/PathwayBrowser/#/R-PFA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Plasmodium falciparum 57923 R-PFA-1676203 https://reactome.org/PathwayBrowser/#/R-PFA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Plasmodium falciparum 57923 R-PFA-8849969 https://reactome.org/PathwayBrowser/#/R-PFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Plasmodium falciparum 57923 R-RNO-1675836 https://reactome.org/PathwayBrowser/#/R-RNO-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Rattus norvegicus 57923 R-RNO-1676005 https://reactome.org/PathwayBrowser/#/R-RNO-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Rattus norvegicus 57923 R-RNO-1676020 https://reactome.org/PathwayBrowser/#/R-RNO-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Rattus norvegicus 57923 R-RNO-1676065 https://reactome.org/PathwayBrowser/#/R-RNO-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Rattus norvegicus 57923 R-RNO-1676105 https://reactome.org/PathwayBrowser/#/R-RNO-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Rattus norvegicus 57923 R-RNO-1676134 https://reactome.org/PathwayBrowser/#/R-RNO-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Rattus norvegicus 57923 R-RNO-1676174 https://reactome.org/PathwayBrowser/#/R-RNO-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Rattus norvegicus 57923 R-RNO-1676203 https://reactome.org/PathwayBrowser/#/R-RNO-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus 57923 R-RNO-5333658 https://reactome.org/PathwayBrowser/#/R-RNO-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Rattus norvegicus 57923 R-RNO-5678490 https://reactome.org/PathwayBrowser/#/R-RNO-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Rattus norvegicus 57923 R-RNO-5679255 https://reactome.org/PathwayBrowser/#/R-RNO-5679255 WIPI2 binds ATG12:ATG5:ATG16L IEA Rattus norvegicus 57923 R-RNO-6809320 https://reactome.org/PathwayBrowser/#/R-RNO-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Rattus norvegicus 57923 R-RNO-6809778 https://reactome.org/PathwayBrowser/#/R-RNO-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Rattus norvegicus 57923 R-RNO-8849969 https://reactome.org/PathwayBrowser/#/R-RNO-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Rattus norvegicus 57923 R-SCE-1675836 https://reactome.org/PathwayBrowser/#/R-SCE-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Saccharomyces cerevisiae 57923 R-SCE-1676065 https://reactome.org/PathwayBrowser/#/R-SCE-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Saccharomyces cerevisiae 57923 R-SCE-1676105 https://reactome.org/PathwayBrowser/#/R-SCE-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Saccharomyces cerevisiae 57923 R-SCE-1676134 https://reactome.org/PathwayBrowser/#/R-SCE-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Saccharomyces cerevisiae 57923 R-SCE-1676203 https://reactome.org/PathwayBrowser/#/R-SCE-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Saccharomyces cerevisiae 57923 R-SCE-5333658 https://reactome.org/PathwayBrowser/#/R-SCE-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Saccharomyces cerevisiae 57923 R-SCE-5678490 https://reactome.org/PathwayBrowser/#/R-SCE-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Saccharomyces cerevisiae 57923 R-SCE-6809320 https://reactome.org/PathwayBrowser/#/R-SCE-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Saccharomyces cerevisiae 57923 R-SCE-6809778 https://reactome.org/PathwayBrowser/#/R-SCE-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Saccharomyces cerevisiae 57923 R-SPO-1675836 https://reactome.org/PathwayBrowser/#/R-SPO-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Schizosaccharomyces pombe 57923 R-SPO-1676065 https://reactome.org/PathwayBrowser/#/R-SPO-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Schizosaccharomyces pombe 57923 R-SPO-1676105 https://reactome.org/PathwayBrowser/#/R-SPO-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Schizosaccharomyces pombe 57923 R-SPO-1676134 https://reactome.org/PathwayBrowser/#/R-SPO-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Schizosaccharomyces pombe 57923 R-SPO-1676203 https://reactome.org/PathwayBrowser/#/R-SPO-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Schizosaccharomyces pombe 57923 R-SPO-5333658 https://reactome.org/PathwayBrowser/#/R-SPO-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Schizosaccharomyces pombe 57923 R-SPO-5678490 https://reactome.org/PathwayBrowser/#/R-SPO-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Schizosaccharomyces pombe 57923 R-SPO-6809320 https://reactome.org/PathwayBrowser/#/R-SPO-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Schizosaccharomyces pombe 57923 R-SPO-6809778 https://reactome.org/PathwayBrowser/#/R-SPO-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Schizosaccharomyces pombe 57923 R-SSC-1675836 https://reactome.org/PathwayBrowser/#/R-SSC-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Sus scrofa 57923 R-SSC-1676005 https://reactome.org/PathwayBrowser/#/R-SSC-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Sus scrofa 57923 R-SSC-1676020 https://reactome.org/PathwayBrowser/#/R-SSC-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Sus scrofa 57923 R-SSC-1676065 https://reactome.org/PathwayBrowser/#/R-SSC-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Sus scrofa 57923 R-SSC-1676105 https://reactome.org/PathwayBrowser/#/R-SSC-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Sus scrofa 57923 R-SSC-1676134 https://reactome.org/PathwayBrowser/#/R-SSC-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Sus scrofa 57923 R-SSC-1676174 https://reactome.org/PathwayBrowser/#/R-SSC-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Sus scrofa 57923 R-SSC-1676203 https://reactome.org/PathwayBrowser/#/R-SSC-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Sus scrofa 57923 R-SSC-5333658 https://reactome.org/PathwayBrowser/#/R-SSC-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Sus scrofa 57923 R-SSC-5678490 https://reactome.org/PathwayBrowser/#/R-SSC-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Sus scrofa 57923 R-SSC-5679255 https://reactome.org/PathwayBrowser/#/R-SSC-5679255 WIPI2 binds ATG12:ATG5:ATG16L IEA Sus scrofa 57923 R-SSC-6809320 https://reactome.org/PathwayBrowser/#/R-SSC-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Sus scrofa 57923 R-SSC-6809778 https://reactome.org/PathwayBrowser/#/R-SSC-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Sus scrofa 57923 R-SSC-8849969 https://reactome.org/PathwayBrowser/#/R-SSC-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Sus scrofa 57923 R-XTR-1675836 https://reactome.org/PathwayBrowser/#/R-XTR-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Xenopus tropicalis 57923 R-XTR-1676065 https://reactome.org/PathwayBrowser/#/R-XTR-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Xenopus tropicalis 57923 R-XTR-1676105 https://reactome.org/PathwayBrowser/#/R-XTR-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Xenopus tropicalis 57923 R-XTR-1676203 https://reactome.org/PathwayBrowser/#/R-XTR-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Xenopus tropicalis 57923 R-XTR-5333658 https://reactome.org/PathwayBrowser/#/R-XTR-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Xenopus tropicalis 57923 R-XTR-5678490 https://reactome.org/PathwayBrowser/#/R-XTR-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Xenopus tropicalis 57923 R-XTR-8849969 https://reactome.org/PathwayBrowser/#/R-XTR-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Xenopus tropicalis 57925 R-BTA-111746 https://reactome.org/PathwayBrowser/#/R-BTA-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Bos taurus 57925 R-BTA-174394 https://reactome.org/PathwayBrowser/#/R-BTA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Bos taurus 57925 R-BTA-176054 https://reactome.org/PathwayBrowser/#/R-BTA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Bos taurus 57925 R-BTA-198813 https://reactome.org/PathwayBrowser/#/R-BTA-198813 GSTO dimers reduce DeHA to AscH- IEA Bos taurus 57925 R-BTA-2161701 https://reactome.org/PathwayBrowser/#/R-BTA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Bos taurus 57925 R-BTA-2161768 https://reactome.org/PathwayBrowser/#/R-BTA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Bos taurus 57925 R-BTA-2161959 https://reactome.org/PathwayBrowser/#/R-BTA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Bos taurus 57925 R-BTA-2161999 https://reactome.org/PathwayBrowser/#/R-BTA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Bos taurus 57925 R-BTA-266050 https://reactome.org/PathwayBrowser/#/R-BTA-266050 LTA4 is converted to LTC4 by LTC4S IEA Bos taurus 57925 R-BTA-3095889 https://reactome.org/PathwayBrowser/#/R-BTA-3095889 MMACHC dealkylates RCbl IEA Bos taurus 57925 R-BTA-3343700 https://reactome.org/PathwayBrowser/#/R-BTA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 57925 R-BTA-5423653 https://reactome.org/PathwayBrowser/#/R-BTA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Bos taurus 57925 R-BTA-5694071 https://reactome.org/PathwayBrowser/#/R-BTA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Bos taurus 57925 R-BTA-5696230 https://reactome.org/PathwayBrowser/#/R-BTA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Bos taurus 57925 R-BTA-6785928 https://reactome.org/PathwayBrowser/#/R-BTA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Bos taurus 57925 R-BTA-71173 https://reactome.org/PathwayBrowser/#/R-BTA-71173 GSTZ1 isomerizes 4-MAA IEA Bos taurus 57925 R-BTA-71676 https://reactome.org/PathwayBrowser/#/R-BTA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Bos taurus 57925 R-BTA-71682 https://reactome.org/PathwayBrowser/#/R-BTA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 57925 R-BTA-9018868 https://reactome.org/PathwayBrowser/#/R-BTA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Bos taurus 57925 R-BTA-9018895 https://reactome.org/PathwayBrowser/#/R-BTA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Bos taurus 57925 R-BTA-9020271 https://reactome.org/PathwayBrowser/#/R-BTA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Bos taurus 57925 R-BTA-9020273 https://reactome.org/PathwayBrowser/#/R-BTA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Bos taurus 57925 R-BTA-9026777 https://reactome.org/PathwayBrowser/#/R-BTA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Bos taurus 57925 R-BTA-9026780 https://reactome.org/PathwayBrowser/#/R-BTA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Bos taurus 57925 R-BTA-9026911 https://reactome.org/PathwayBrowser/#/R-BTA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Bos taurus 57925 R-BTA-9748996 https://reactome.org/PathwayBrowser/#/R-BTA-9748996 GST dimers cleave AZA to 6MP IEA Bos taurus 57925 R-BTA-9753280 https://reactome.org/PathwayBrowser/#/R-BTA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Bos taurus 57925 R-CEL-111746 https://reactome.org/PathwayBrowser/#/R-CEL-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Caenorhabditis elegans 57925 R-CEL-174394 https://reactome.org/PathwayBrowser/#/R-CEL-174394 GSS:Mg2+ dimer synthesizes GSH IEA Caenorhabditis elegans 57925 R-CEL-176054 https://reactome.org/PathwayBrowser/#/R-CEL-176054 GST dimers conjugate GSH with cytosolic substrates IEA Caenorhabditis elegans 57925 R-CEL-198813 https://reactome.org/PathwayBrowser/#/R-CEL-198813 GSTO dimers reduce DeHA to AscH- IEA Caenorhabditis elegans 57925 R-CEL-2161701 https://reactome.org/PathwayBrowser/#/R-CEL-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Caenorhabditis elegans 57925 R-CEL-2161959 https://reactome.org/PathwayBrowser/#/R-CEL-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Caenorhabditis elegans 57925 R-CEL-2161999 https://reactome.org/PathwayBrowser/#/R-CEL-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Caenorhabditis elegans 57925 R-CEL-3095889 https://reactome.org/PathwayBrowser/#/R-CEL-3095889 MMACHC dealkylates RCbl IEA Caenorhabditis elegans 57925 R-CEL-3343700 https://reactome.org/PathwayBrowser/#/R-CEL-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Caenorhabditis elegans 57925 R-CEL-5696230 https://reactome.org/PathwayBrowser/#/R-CEL-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Caenorhabditis elegans 57925 R-CEL-6785928 https://reactome.org/PathwayBrowser/#/R-CEL-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Caenorhabditis elegans 57925 R-CEL-71173 https://reactome.org/PathwayBrowser/#/R-CEL-71173 GSTZ1 isomerizes 4-MAA IEA Caenorhabditis elegans 57925 R-CEL-71682 https://reactome.org/PathwayBrowser/#/R-CEL-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 57925 R-CEL-9018868 https://reactome.org/PathwayBrowser/#/R-CEL-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Caenorhabditis elegans 57925 R-CEL-9018895 https://reactome.org/PathwayBrowser/#/R-CEL-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Caenorhabditis elegans 57925 R-CEL-9020271 https://reactome.org/PathwayBrowser/#/R-CEL-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Caenorhabditis elegans 57925 R-CEL-9020273 https://reactome.org/PathwayBrowser/#/R-CEL-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Caenorhabditis elegans 57925 R-CEL-9753280 https://reactome.org/PathwayBrowser/#/R-CEL-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Caenorhabditis elegans 57925 R-CFA-111746 https://reactome.org/PathwayBrowser/#/R-CFA-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Canis familiaris 57925 R-CFA-174394 https://reactome.org/PathwayBrowser/#/R-CFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Canis familiaris 57925 R-CFA-176054 https://reactome.org/PathwayBrowser/#/R-CFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Canis familiaris 57925 R-CFA-198813 https://reactome.org/PathwayBrowser/#/R-CFA-198813 GSTO dimers reduce DeHA to AscH- IEA Canis familiaris 57925 R-CFA-2161701 https://reactome.org/PathwayBrowser/#/R-CFA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Canis familiaris 57925 R-CFA-2161768 https://reactome.org/PathwayBrowser/#/R-CFA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Canis familiaris 57925 R-CFA-2161791 https://reactome.org/PathwayBrowser/#/R-CFA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Canis familiaris 57925 R-CFA-2161959 https://reactome.org/PathwayBrowser/#/R-CFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Canis familiaris 57925 R-CFA-2161999 https://reactome.org/PathwayBrowser/#/R-CFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Canis familiaris 57925 R-CFA-266050 https://reactome.org/PathwayBrowser/#/R-CFA-266050 LTA4 is converted to LTC4 by LTC4S IEA Canis familiaris 57925 R-CFA-3095889 https://reactome.org/PathwayBrowser/#/R-CFA-3095889 MMACHC dealkylates RCbl IEA Canis familiaris 57925 R-CFA-3341277 https://reactome.org/PathwayBrowser/#/R-CFA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 57925 R-CFA-3343700 https://reactome.org/PathwayBrowser/#/R-CFA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 57925 R-CFA-5423653 https://reactome.org/PathwayBrowser/#/R-CFA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Canis familiaris 57925 R-CFA-5694071 https://reactome.org/PathwayBrowser/#/R-CFA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Canis familiaris 57925 R-CFA-5696230 https://reactome.org/PathwayBrowser/#/R-CFA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Canis familiaris 57925 R-CFA-6785928 https://reactome.org/PathwayBrowser/#/R-CFA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Canis familiaris 57925 R-CFA-71173 https://reactome.org/PathwayBrowser/#/R-CFA-71173 GSTZ1 isomerizes 4-MAA IEA Canis familiaris 57925 R-CFA-71676 https://reactome.org/PathwayBrowser/#/R-CFA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Canis familiaris 57925 R-CFA-71682 https://reactome.org/PathwayBrowser/#/R-CFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 57925 R-CFA-9018868 https://reactome.org/PathwayBrowser/#/R-CFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Canis familiaris 57925 R-CFA-9018895 https://reactome.org/PathwayBrowser/#/R-CFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Canis familiaris 57925 R-CFA-9020271 https://reactome.org/PathwayBrowser/#/R-CFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Canis familiaris 57925 R-CFA-9020273 https://reactome.org/PathwayBrowser/#/R-CFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Canis familiaris 57925 R-CFA-9026777 https://reactome.org/PathwayBrowser/#/R-CFA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Canis familiaris 57925 R-CFA-9026780 https://reactome.org/PathwayBrowser/#/R-CFA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Canis familiaris 57925 R-CFA-9026911 https://reactome.org/PathwayBrowser/#/R-CFA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Canis familiaris 57925 R-CFA-9748996 https://reactome.org/PathwayBrowser/#/R-CFA-9748996 GST dimers cleave AZA to 6MP IEA Canis familiaris 57925 R-CFA-9753280 https://reactome.org/PathwayBrowser/#/R-CFA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Canis familiaris 57925 R-DDI-174394 https://reactome.org/PathwayBrowser/#/R-DDI-174394 GSS:Mg2+ dimer synthesizes GSH IEA Dictyostelium discoideum 57925 R-DDI-176054 https://reactome.org/PathwayBrowser/#/R-DDI-176054 GST dimers conjugate GSH with cytosolic substrates IEA Dictyostelium discoideum 57925 R-DDI-2161701 https://reactome.org/PathwayBrowser/#/R-DDI-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Dictyostelium discoideum 57925 R-DDI-2161768 https://reactome.org/PathwayBrowser/#/R-DDI-2161768 EXA4 is converted to EXC4 by LTC4S IEA Dictyostelium discoideum 57925 R-DDI-266050 https://reactome.org/PathwayBrowser/#/R-DDI-266050 LTA4 is converted to LTC4 by LTC4S IEA Dictyostelium discoideum 57925 R-DDI-3095889 https://reactome.org/PathwayBrowser/#/R-DDI-3095889 MMACHC dealkylates RCbl IEA Dictyostelium discoideum 57925 R-DDI-3343700 https://reactome.org/PathwayBrowser/#/R-DDI-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Dictyostelium discoideum 57925 R-DDI-5423653 https://reactome.org/PathwayBrowser/#/R-DDI-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Dictyostelium discoideum 57925 R-DDI-6785928 https://reactome.org/PathwayBrowser/#/R-DDI-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Dictyostelium discoideum 57925 R-DDI-71173 https://reactome.org/PathwayBrowser/#/R-DDI-71173 GSTZ1 isomerizes 4-MAA IEA Dictyostelium discoideum 57925 R-DDI-71682 https://reactome.org/PathwayBrowser/#/R-DDI-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 57925 R-DDI-9026780 https://reactome.org/PathwayBrowser/#/R-DDI-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Dictyostelium discoideum 57925 R-DDI-9026911 https://reactome.org/PathwayBrowser/#/R-DDI-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Dictyostelium discoideum 57925 R-DDI-9748996 https://reactome.org/PathwayBrowser/#/R-DDI-9748996 GST dimers cleave AZA to 6MP IEA Dictyostelium discoideum 57925 R-DDI-9753280 https://reactome.org/PathwayBrowser/#/R-DDI-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Dictyostelium discoideum 57925 R-DME-174394 https://reactome.org/PathwayBrowser/#/R-DME-174394 GSS:Mg2+ dimer synthesizes GSH IEA Drosophila melanogaster 57925 R-DME-176054 https://reactome.org/PathwayBrowser/#/R-DME-176054 GST dimers conjugate GSH with cytosolic substrates IEA Drosophila melanogaster 57925 R-DME-198813 https://reactome.org/PathwayBrowser/#/R-DME-198813 GSTO dimers reduce DeHA to AscH- IEA Drosophila melanogaster 57925 R-DME-2161701 https://reactome.org/PathwayBrowser/#/R-DME-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Drosophila melanogaster 57925 R-DME-5423653 https://reactome.org/PathwayBrowser/#/R-DME-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Drosophila melanogaster 57925 R-DME-5694071 https://reactome.org/PathwayBrowser/#/R-DME-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Drosophila melanogaster 57925 R-DME-5696230 https://reactome.org/PathwayBrowser/#/R-DME-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Drosophila melanogaster 57925 R-DME-6785928 https://reactome.org/PathwayBrowser/#/R-DME-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Drosophila melanogaster 57925 R-DME-71173 https://reactome.org/PathwayBrowser/#/R-DME-71173 GSTZ1 isomerizes 4-MAA IEA Drosophila melanogaster 57925 R-DME-9753280 https://reactome.org/PathwayBrowser/#/R-DME-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Drosophila melanogaster 57925 R-DRE-111746 https://reactome.org/PathwayBrowser/#/R-DRE-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Danio rerio 57925 R-DRE-174394 https://reactome.org/PathwayBrowser/#/R-DRE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Danio rerio 57925 R-DRE-176054 https://reactome.org/PathwayBrowser/#/R-DRE-176054 GST dimers conjugate GSH with cytosolic substrates IEA Danio rerio 57925 R-DRE-198813 https://reactome.org/PathwayBrowser/#/R-DRE-198813 GSTO dimers reduce DeHA to AscH- IEA Danio rerio 57925 R-DRE-3095889 https://reactome.org/PathwayBrowser/#/R-DRE-3095889 MMACHC dealkylates RCbl IEA Danio rerio 57925 R-DRE-3343700 https://reactome.org/PathwayBrowser/#/R-DRE-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Danio rerio 57925 R-DRE-5423653 https://reactome.org/PathwayBrowser/#/R-DRE-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Danio rerio 57925 R-DRE-5694071 https://reactome.org/PathwayBrowser/#/R-DRE-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Danio rerio 57925 R-DRE-5696230 https://reactome.org/PathwayBrowser/#/R-DRE-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Danio rerio 57925 R-DRE-6785928 https://reactome.org/PathwayBrowser/#/R-DRE-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Danio rerio 57925 R-DRE-71173 https://reactome.org/PathwayBrowser/#/R-DRE-71173 GSTZ1 isomerizes 4-MAA IEA Danio rerio 57925 R-DRE-9026777 https://reactome.org/PathwayBrowser/#/R-DRE-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Danio rerio 57925 R-DRE-9748996 https://reactome.org/PathwayBrowser/#/R-DRE-9748996 GST dimers cleave AZA to 6MP IEA Danio rerio 57925 R-DRE-9753280 https://reactome.org/PathwayBrowser/#/R-DRE-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Danio rerio 57925 R-GGA-111746 https://reactome.org/PathwayBrowser/#/R-GGA-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Gallus gallus 57925 R-GGA-174394 https://reactome.org/PathwayBrowser/#/R-GGA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Gallus gallus 57925 R-GGA-176054 https://reactome.org/PathwayBrowser/#/R-GGA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Gallus gallus 57925 R-GGA-198813 https://reactome.org/PathwayBrowser/#/R-GGA-198813 GSTO dimers reduce DeHA to AscH- IEA Gallus gallus 57925 R-GGA-2161701 https://reactome.org/PathwayBrowser/#/R-GGA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Gallus gallus 57925 R-GGA-2161768 https://reactome.org/PathwayBrowser/#/R-GGA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Gallus gallus 57925 R-GGA-2161959 https://reactome.org/PathwayBrowser/#/R-GGA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Gallus gallus 57925 R-GGA-2161999 https://reactome.org/PathwayBrowser/#/R-GGA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Gallus gallus 57925 R-GGA-266050 https://reactome.org/PathwayBrowser/#/R-GGA-266050 LTA4 is converted to LTC4 by LTC4S IEA Gallus gallus 57925 R-GGA-3095889 https://reactome.org/PathwayBrowser/#/R-GGA-3095889 MMACHC dealkylates RCbl IEA Gallus gallus 57925 R-GGA-3341277 https://reactome.org/PathwayBrowser/#/R-GGA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Gallus gallus 57925 R-GGA-5423653 https://reactome.org/PathwayBrowser/#/R-GGA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Gallus gallus 57925 R-GGA-5694071 https://reactome.org/PathwayBrowser/#/R-GGA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Gallus gallus 57925 R-GGA-5696230 https://reactome.org/PathwayBrowser/#/R-GGA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Gallus gallus 57925 R-GGA-6785928 https://reactome.org/PathwayBrowser/#/R-GGA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Gallus gallus 57925 R-GGA-71173 https://reactome.org/PathwayBrowser/#/R-GGA-71173 GSTZ1 isomerizes 4-MAA IEA Gallus gallus 57925 R-GGA-71682 https://reactome.org/PathwayBrowser/#/R-GGA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 57925 R-GGA-9018868 https://reactome.org/PathwayBrowser/#/R-GGA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Gallus gallus 57925 R-GGA-9018895 https://reactome.org/PathwayBrowser/#/R-GGA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Gallus gallus 57925 R-GGA-9020271 https://reactome.org/PathwayBrowser/#/R-GGA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Gallus gallus 57925 R-GGA-9020273 https://reactome.org/PathwayBrowser/#/R-GGA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Gallus gallus 57925 R-GGA-9026777 https://reactome.org/PathwayBrowser/#/R-GGA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Gallus gallus 57925 R-GGA-9026780 https://reactome.org/PathwayBrowser/#/R-GGA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Gallus gallus 57925 R-GGA-9026911 https://reactome.org/PathwayBrowser/#/R-GGA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Gallus gallus 57925 R-GGA-9748996 https://reactome.org/PathwayBrowser/#/R-GGA-9748996 GST dimers cleave AZA to 6MP IEA Gallus gallus 57925 R-GGA-9753280 https://reactome.org/PathwayBrowser/#/R-GGA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Gallus gallus 57925 R-HSA-111746 https://reactome.org/PathwayBrowser/#/R-HSA-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) TAS Homo sapiens 57925 R-HSA-1222384 https://reactome.org/PathwayBrowser/#/R-HSA-1222384 Glutathione scavenges nitrosyl TAS Homo sapiens 57925 R-HSA-1247915 https://reactome.org/PathwayBrowser/#/R-HSA-1247915 GSH translocates from cytosol to extracellular region TAS Homo sapiens 57925 R-HSA-1500817 https://reactome.org/PathwayBrowser/#/R-HSA-1500817 Glutathione is taken up by the bacterium TAS Homo sapiens 57925 R-HSA-174394 https://reactome.org/PathwayBrowser/#/R-HSA-174394 GSS:Mg2+ dimer synthesizes GSH TAS Homo sapiens 57925 R-HSA-176054 https://reactome.org/PathwayBrowser/#/R-HSA-176054 GST dimers conjugate GSH with cytosolic substrates TAS Homo sapiens 57925 R-HSA-198813 https://reactome.org/PathwayBrowser/#/R-HSA-198813 GSTO dimers reduce DeHA to AscH- TAS Homo sapiens 57925 R-HSA-2161701 https://reactome.org/PathwayBrowser/#/R-HSA-2161701 PGH2 is isomerised to PGD2 by HPGDS TAS Homo sapiens 57925 R-HSA-2161768 https://reactome.org/PathwayBrowser/#/R-HSA-2161768 EXA4 is converted to EXC4 by LTC4S TAS Homo sapiens 57925 R-HSA-2161791 https://reactome.org/PathwayBrowser/#/R-HSA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 TAS Homo sapiens 57925 R-HSA-2161946 https://reactome.org/PathwayBrowser/#/R-HSA-2161946 5S-HpETE is reduced to 5S-HETE by GPX1/2/4 IEA Homo sapiens 57925 R-HSA-2161959 https://reactome.org/PathwayBrowser/#/R-HSA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 TAS Homo sapiens 57925 R-HSA-2161999 https://reactome.org/PathwayBrowser/#/R-HSA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 TAS Homo sapiens 57925 R-HSA-2408500 https://reactome.org/PathwayBrowser/#/R-HSA-2408500 GSSeH condenses with GSH to form H2Se and GSSG IEA Homo sapiens 57925 R-HSA-2408542 https://reactome.org/PathwayBrowser/#/R-HSA-2408542 GSSeSG is reduced to GSSeH and GSH by GSR IEA Homo sapiens 57925 R-HSA-2408556 https://reactome.org/PathwayBrowser/#/R-HSA-2408556 SeO3(2-) combines with GSH to form GSSeSG and GSSG IEA Homo sapiens 57925 R-HSA-266050 https://reactome.org/PathwayBrowser/#/R-HSA-266050 LTA4 is converted to LTC4 by LTC4S TAS Homo sapiens 57925 R-HSA-3095889 https://reactome.org/PathwayBrowser/#/R-HSA-3095889 MMACHC dealkylates RCbl TAS Homo sapiens 57925 R-HSA-3341277 https://reactome.org/PathwayBrowser/#/R-HSA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 57925 R-HSA-3343700 https://reactome.org/PathwayBrowser/#/R-HSA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 57925 R-HSA-5333608 https://reactome.org/PathwayBrowser/#/R-HSA-5333608 GSSebGalNac is reduced and methylated to MeSebGalNac IEA Homo sapiens 57925 R-HSA-5423653 https://reactome.org/PathwayBrowser/#/R-HSA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO TAS Homo sapiens 57925 R-HSA-5694071 https://reactome.org/PathwayBrowser/#/R-HSA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH TAS Homo sapiens 57925 R-HSA-5696230 https://reactome.org/PathwayBrowser/#/R-HSA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite TAS Homo sapiens 57925 R-HSA-6785928 https://reactome.org/PathwayBrowser/#/R-HSA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly TAS Homo sapiens 57925 R-HSA-71173 https://reactome.org/PathwayBrowser/#/R-HSA-71173 GSTZ1 isomerizes 4-MAA TAS Homo sapiens 57925 R-HSA-71676 https://reactome.org/PathwayBrowser/#/R-HSA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O TAS Homo sapiens 57925 R-HSA-71682 https://reactome.org/PathwayBrowser/#/R-HSA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 57925 R-HSA-9018868 https://reactome.org/PathwayBrowser/#/R-HSA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE TAS Homo sapiens 57925 R-HSA-9018895 https://reactome.org/PathwayBrowser/#/R-HSA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE TAS Homo sapiens 57925 R-HSA-9020271 https://reactome.org/PathwayBrowser/#/R-HSA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA TAS Homo sapiens 57925 R-HSA-9020273 https://reactome.org/PathwayBrowser/#/R-HSA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA TAS Homo sapiens 57925 R-HSA-9026777 https://reactome.org/PathwayBrowser/#/R-HSA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 TAS Homo sapiens 57925 R-HSA-9026780 https://reactome.org/PathwayBrowser/#/R-HSA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 TAS Homo sapiens 57925 R-HSA-9026901 https://reactome.org/PathwayBrowser/#/R-HSA-9026901 GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1 TAS Homo sapiens 57925 R-HSA-9026911 https://reactome.org/PathwayBrowser/#/R-HSA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 TAS Homo sapiens 57925 R-HSA-9748996 https://reactome.org/PathwayBrowser/#/R-HSA-9748996 GST dimers cleave AZA to 6MP TAS Homo sapiens 57925 R-HSA-9751051 https://reactome.org/PathwayBrowser/#/R-HSA-9751051 GSH cleaves AZA to 6MP TAS Homo sapiens 57925 R-HSA-9753280 https://reactome.org/PathwayBrowser/#/R-HSA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG TAS Homo sapiens 57925 R-MMU-111746 https://reactome.org/PathwayBrowser/#/R-MMU-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Mus musculus 57925 R-MMU-174394 https://reactome.org/PathwayBrowser/#/R-MMU-174394 GSS:Mg2+ dimer synthesizes GSH IEA Mus musculus 57925 R-MMU-176054 https://reactome.org/PathwayBrowser/#/R-MMU-176054 GST dimers conjugate GSH with cytosolic substrates IEA Mus musculus 57925 R-MMU-198813 https://reactome.org/PathwayBrowser/#/R-MMU-198813 GSTO dimers reduce DeHA to AscH- IEA Mus musculus 57925 R-MMU-2161701 https://reactome.org/PathwayBrowser/#/R-MMU-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Mus musculus 57925 R-MMU-2161768 https://reactome.org/PathwayBrowser/#/R-MMU-2161768 EXA4 is converted to EXC4 by LTC4S IEA Mus musculus 57925 R-MMU-2161791 https://reactome.org/PathwayBrowser/#/R-MMU-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Mus musculus 57925 R-MMU-2161959 https://reactome.org/PathwayBrowser/#/R-MMU-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Mus musculus 57925 R-MMU-2161999 https://reactome.org/PathwayBrowser/#/R-MMU-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Mus musculus 57925 R-MMU-266050 https://reactome.org/PathwayBrowser/#/R-MMU-266050 LTA4 is converted to LTC4 by LTC4S IEA Mus musculus 57925 R-MMU-3095889 https://reactome.org/PathwayBrowser/#/R-MMU-3095889 MMACHC dealkylates RCbl IEA Mus musculus 57925 R-MMU-3341277 https://reactome.org/PathwayBrowser/#/R-MMU-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 57925 R-MMU-3343700 https://reactome.org/PathwayBrowser/#/R-MMU-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 57925 R-MMU-5423653 https://reactome.org/PathwayBrowser/#/R-MMU-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Mus musculus 57925 R-MMU-5694071 https://reactome.org/PathwayBrowser/#/R-MMU-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Mus musculus 57925 R-MMU-5696230 https://reactome.org/PathwayBrowser/#/R-MMU-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Mus musculus 57925 R-MMU-6785928 https://reactome.org/PathwayBrowser/#/R-MMU-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Mus musculus 57925 R-MMU-71173 https://reactome.org/PathwayBrowser/#/R-MMU-71173 GSTZ1 isomerizes 4-MAA IEA Mus musculus 57925 R-MMU-71676 https://reactome.org/PathwayBrowser/#/R-MMU-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Mus musculus 57925 R-MMU-71682 https://reactome.org/PathwayBrowser/#/R-MMU-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 57925 R-MMU-9018868 https://reactome.org/PathwayBrowser/#/R-MMU-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Mus musculus 57925 R-MMU-9018895 https://reactome.org/PathwayBrowser/#/R-MMU-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Mus musculus 57925 R-MMU-9020271 https://reactome.org/PathwayBrowser/#/R-MMU-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Mus musculus 57925 R-MMU-9020273 https://reactome.org/PathwayBrowser/#/R-MMU-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Mus musculus 57925 R-MMU-9026777 https://reactome.org/PathwayBrowser/#/R-MMU-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Mus musculus 57925 R-MMU-9026780 https://reactome.org/PathwayBrowser/#/R-MMU-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Mus musculus 57925 R-MMU-9026911 https://reactome.org/PathwayBrowser/#/R-MMU-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Mus musculus 57925 R-MMU-9748996 https://reactome.org/PathwayBrowser/#/R-MMU-9748996 GST dimers cleave AZA to 6MP IEA Mus musculus 57925 R-MMU-9753280 https://reactome.org/PathwayBrowser/#/R-MMU-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Mus musculus 57925 R-OCU-2161896 https://reactome.org/PathwayBrowser/#/R-OCU-2161896 5S-HpETE is reduced to 5S-HETE by GPX1 TAS Oryctolagus cuniculus 57925 R-PFA-111746 https://reactome.org/PathwayBrowser/#/R-PFA-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Plasmodium falciparum 57925 R-PFA-174394 https://reactome.org/PathwayBrowser/#/R-PFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Plasmodium falciparum 57925 R-PFA-176054 https://reactome.org/PathwayBrowser/#/R-PFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Plasmodium falciparum 57925 R-PFA-2161701 https://reactome.org/PathwayBrowser/#/R-PFA-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Plasmodium falciparum 57925 R-PFA-2161959 https://reactome.org/PathwayBrowser/#/R-PFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Plasmodium falciparum 57925 R-PFA-2161999 https://reactome.org/PathwayBrowser/#/R-PFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Plasmodium falciparum 57925 R-PFA-3343700 https://reactome.org/PathwayBrowser/#/R-PFA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Plasmodium falciparum 57925 R-PFA-5694071 https://reactome.org/PathwayBrowser/#/R-PFA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Plasmodium falciparum 57925 R-PFA-71682 https://reactome.org/PathwayBrowser/#/R-PFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 57925 R-PFA-9018868 https://reactome.org/PathwayBrowser/#/R-PFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Plasmodium falciparum 57925 R-PFA-9018895 https://reactome.org/PathwayBrowser/#/R-PFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Plasmodium falciparum 57925 R-PFA-9020271 https://reactome.org/PathwayBrowser/#/R-PFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Plasmodium falciparum 57925 R-PFA-9020273 https://reactome.org/PathwayBrowser/#/R-PFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Plasmodium falciparum 57925 R-PFA-9748996 https://reactome.org/PathwayBrowser/#/R-PFA-9748996 GST dimers cleave AZA to 6MP IEA Plasmodium falciparum 57925 R-PFA-9753280 https://reactome.org/PathwayBrowser/#/R-PFA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Plasmodium falciparum 57925 R-RNO-111746 https://reactome.org/PathwayBrowser/#/R-RNO-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Rattus norvegicus 57925 R-RNO-174394 https://reactome.org/PathwayBrowser/#/R-RNO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Rattus norvegicus 57925 R-RNO-176054 https://reactome.org/PathwayBrowser/#/R-RNO-176054 GST dimers conjugate GSH with cytosolic substrates IEA Rattus norvegicus 57925 R-RNO-198813 https://reactome.org/PathwayBrowser/#/R-RNO-198813 GSTO dimers reduce DeHA to AscH- IEA Rattus norvegicus 57925 R-RNO-2161701 https://reactome.org/PathwayBrowser/#/R-RNO-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Rattus norvegicus 57925 R-RNO-2161768 https://reactome.org/PathwayBrowser/#/R-RNO-2161768 EXA4 is converted to EXC4 by LTC4S IEA Rattus norvegicus 57925 R-RNO-2161791 https://reactome.org/PathwayBrowser/#/R-RNO-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Rattus norvegicus 57925 R-RNO-2161959 https://reactome.org/PathwayBrowser/#/R-RNO-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Rattus norvegicus 57925 R-RNO-2161999 https://reactome.org/PathwayBrowser/#/R-RNO-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Rattus norvegicus 57925 R-RNO-2408514 https://reactome.org/PathwayBrowser/#/R-RNO-2408514 GSSeSG is reduced to GSSeH and GSH by Gsr TAS Rattus norvegicus 57925 R-RNO-2408520 https://reactome.org/PathwayBrowser/#/R-RNO-2408520 GSSeH condenses with GSH to form H2Se and GSSG TAS Rattus norvegicus 57925 R-RNO-2408553 https://reactome.org/PathwayBrowser/#/R-RNO-2408553 SeO3(2-) combines with GSH to form GSSeSG and GSSG TAS Rattus norvegicus 57925 R-RNO-266050 https://reactome.org/PathwayBrowser/#/R-RNO-266050 LTA4 is converted to LTC4 by LTC4S IEA Rattus norvegicus 57925 R-RNO-3095889 https://reactome.org/PathwayBrowser/#/R-RNO-3095889 MMACHC dealkylates RCbl IEA Rattus norvegicus 57925 R-RNO-3341277 https://reactome.org/PathwayBrowser/#/R-RNO-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 57925 R-RNO-3343700 https://reactome.org/PathwayBrowser/#/R-RNO-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 57925 R-RNO-5333614 https://reactome.org/PathwayBrowser/#/R-RNO-5333614 GSSebGalNac is reduced and methylated to MeSebGalNac TAS Rattus norvegicus 57925 R-RNO-5423653 https://reactome.org/PathwayBrowser/#/R-RNO-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Rattus norvegicus 57925 R-RNO-5694071 https://reactome.org/PathwayBrowser/#/R-RNO-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Rattus norvegicus 57925 R-RNO-5696230 https://reactome.org/PathwayBrowser/#/R-RNO-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Rattus norvegicus 57925 R-RNO-6785928 https://reactome.org/PathwayBrowser/#/R-RNO-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Rattus norvegicus 57925 R-RNO-71173 https://reactome.org/PathwayBrowser/#/R-RNO-71173 GSTZ1 isomerizes 4-MAA IEA Rattus norvegicus 57925 R-RNO-71676 https://reactome.org/PathwayBrowser/#/R-RNO-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Rattus norvegicus 57925 R-RNO-71682 https://reactome.org/PathwayBrowser/#/R-RNO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 57925 R-RNO-9018868 https://reactome.org/PathwayBrowser/#/R-RNO-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Rattus norvegicus 57925 R-RNO-9018895 https://reactome.org/PathwayBrowser/#/R-RNO-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Rattus norvegicus 57925 R-RNO-9020271 https://reactome.org/PathwayBrowser/#/R-RNO-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Rattus norvegicus 57925 R-RNO-9020273 https://reactome.org/PathwayBrowser/#/R-RNO-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Rattus norvegicus 57925 R-RNO-9026777 https://reactome.org/PathwayBrowser/#/R-RNO-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Rattus norvegicus 57925 R-RNO-9026780 https://reactome.org/PathwayBrowser/#/R-RNO-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Rattus norvegicus 57925 R-RNO-9026911 https://reactome.org/PathwayBrowser/#/R-RNO-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Rattus norvegicus 57925 R-RNO-9748996 https://reactome.org/PathwayBrowser/#/R-RNO-9748996 GST dimers cleave AZA to 6MP IEA Rattus norvegicus 57925 R-RNO-9753280 https://reactome.org/PathwayBrowser/#/R-RNO-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Rattus norvegicus 57925 R-SCE-174394 https://reactome.org/PathwayBrowser/#/R-SCE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Saccharomyces cerevisiae 57925 R-SCE-5694071 https://reactome.org/PathwayBrowser/#/R-SCE-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Saccharomyces cerevisiae 57925 R-SCE-6785928 https://reactome.org/PathwayBrowser/#/R-SCE-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Saccharomyces cerevisiae 57925 R-SCE-71682 https://reactome.org/PathwayBrowser/#/R-SCE-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 57925 R-SPO-174394 https://reactome.org/PathwayBrowser/#/R-SPO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Schizosaccharomyces pombe 57925 R-SPO-5694071 https://reactome.org/PathwayBrowser/#/R-SPO-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Schizosaccharomyces pombe 57925 R-SPO-6785928 https://reactome.org/PathwayBrowser/#/R-SPO-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Schizosaccharomyces pombe 57925 R-SPO-71682 https://reactome.org/PathwayBrowser/#/R-SPO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 57925 R-SSC-111746 https://reactome.org/PathwayBrowser/#/R-SSC-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Sus scrofa 57925 R-SSC-174394 https://reactome.org/PathwayBrowser/#/R-SSC-174394 GSS:Mg2+ dimer synthesizes GSH IEA Sus scrofa 57925 R-SSC-176054 https://reactome.org/PathwayBrowser/#/R-SSC-176054 GST dimers conjugate GSH with cytosolic substrates IEA Sus scrofa 57925 R-SSC-198813 https://reactome.org/PathwayBrowser/#/R-SSC-198813 GSTO dimers reduce DeHA to AscH- IEA Sus scrofa 57925 R-SSC-2161701 https://reactome.org/PathwayBrowser/#/R-SSC-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Sus scrofa 57925 R-SSC-2161768 https://reactome.org/PathwayBrowser/#/R-SSC-2161768 EXA4 is converted to EXC4 by LTC4S IEA Sus scrofa 57925 R-SSC-2161791 https://reactome.org/PathwayBrowser/#/R-SSC-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Sus scrofa 57925 R-SSC-2161959 https://reactome.org/PathwayBrowser/#/R-SSC-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Sus scrofa 57925 R-SSC-2161999 https://reactome.org/PathwayBrowser/#/R-SSC-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Sus scrofa 57925 R-SSC-266050 https://reactome.org/PathwayBrowser/#/R-SSC-266050 LTA4 is converted to LTC4 by LTC4S IEA Sus scrofa 57925 R-SSC-3095889 https://reactome.org/PathwayBrowser/#/R-SSC-3095889 MMACHC dealkylates RCbl IEA Sus scrofa 57925 R-SSC-3341277 https://reactome.org/PathwayBrowser/#/R-SSC-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 57925 R-SSC-3343700 https://reactome.org/PathwayBrowser/#/R-SSC-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 57925 R-SSC-5423653 https://reactome.org/PathwayBrowser/#/R-SSC-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Sus scrofa 57925 R-SSC-5694071 https://reactome.org/PathwayBrowser/#/R-SSC-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Sus scrofa 57925 R-SSC-5696230 https://reactome.org/PathwayBrowser/#/R-SSC-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Sus scrofa 57925 R-SSC-6785928 https://reactome.org/PathwayBrowser/#/R-SSC-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Sus scrofa 57925 R-SSC-71173 https://reactome.org/PathwayBrowser/#/R-SSC-71173 GSTZ1 isomerizes 4-MAA IEA Sus scrofa 57925 R-SSC-71676 https://reactome.org/PathwayBrowser/#/R-SSC-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Sus scrofa 57925 R-SSC-71682 https://reactome.org/PathwayBrowser/#/R-SSC-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 57925 R-SSC-9018868 https://reactome.org/PathwayBrowser/#/R-SSC-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Sus scrofa 57925 R-SSC-9018895 https://reactome.org/PathwayBrowser/#/R-SSC-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Sus scrofa 57925 R-SSC-9020271 https://reactome.org/PathwayBrowser/#/R-SSC-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Sus scrofa 57925 R-SSC-9020273 https://reactome.org/PathwayBrowser/#/R-SSC-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Sus scrofa 57925 R-SSC-9026777 https://reactome.org/PathwayBrowser/#/R-SSC-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Sus scrofa 57925 R-SSC-9026780 https://reactome.org/PathwayBrowser/#/R-SSC-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Sus scrofa 57925 R-SSC-9026911 https://reactome.org/PathwayBrowser/#/R-SSC-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Sus scrofa 57925 R-SSC-9748996 https://reactome.org/PathwayBrowser/#/R-SSC-9748996 GST dimers cleave AZA to 6MP IEA Sus scrofa 57925 R-SSC-9753280 https://reactome.org/PathwayBrowser/#/R-SSC-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Sus scrofa 57925 R-XTR-111746 https://reactome.org/PathwayBrowser/#/R-XTR-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Xenopus tropicalis 57925 R-XTR-176054 https://reactome.org/PathwayBrowser/#/R-XTR-176054 GST dimers conjugate GSH with cytosolic substrates IEA Xenopus tropicalis 57925 R-XTR-198813 https://reactome.org/PathwayBrowser/#/R-XTR-198813 GSTO dimers reduce DeHA to AscH- IEA Xenopus tropicalis 57925 R-XTR-2161701 https://reactome.org/PathwayBrowser/#/R-XTR-2161701 PGH2 is isomerised to PGD2 by HPGDS IEA Xenopus tropicalis 57925 R-XTR-2161768 https://reactome.org/PathwayBrowser/#/R-XTR-2161768 EXA4 is converted to EXC4 by LTC4S IEA Xenopus tropicalis 57925 R-XTR-266050 https://reactome.org/PathwayBrowser/#/R-XTR-266050 LTA4 is converted to LTC4 by LTC4S IEA Xenopus tropicalis 57925 R-XTR-3095889 https://reactome.org/PathwayBrowser/#/R-XTR-3095889 MMACHC dealkylates RCbl IEA Xenopus tropicalis 57925 R-XTR-3343700 https://reactome.org/PathwayBrowser/#/R-XTR-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Xenopus tropicalis 57925 R-XTR-5423653 https://reactome.org/PathwayBrowser/#/R-XTR-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Xenopus tropicalis 57925 R-XTR-5694071 https://reactome.org/PathwayBrowser/#/R-XTR-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Xenopus tropicalis 57925 R-XTR-5696230 https://reactome.org/PathwayBrowser/#/R-XTR-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Xenopus tropicalis 57925 R-XTR-6785928 https://reactome.org/PathwayBrowser/#/R-XTR-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Xenopus tropicalis 57925 R-XTR-71173 https://reactome.org/PathwayBrowser/#/R-XTR-71173 GSTZ1 isomerizes 4-MAA IEA Xenopus tropicalis 57925 R-XTR-71682 https://reactome.org/PathwayBrowser/#/R-XTR-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 57925 R-XTR-9026777 https://reactome.org/PathwayBrowser/#/R-XTR-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Xenopus tropicalis 57925 R-XTR-9026780 https://reactome.org/PathwayBrowser/#/R-XTR-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Xenopus tropicalis 57925 R-XTR-9026911 https://reactome.org/PathwayBrowser/#/R-XTR-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Xenopus tropicalis 57925 R-XTR-9748996 https://reactome.org/PathwayBrowser/#/R-XTR-9748996 GST dimers cleave AZA to 6MP IEA Xenopus tropicalis 57925 R-XTR-9753280 https://reactome.org/PathwayBrowser/#/R-XTR-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Xenopus tropicalis 57926 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 57926 R-BTA-352108 https://reactome.org/PathwayBrowser/#/R-BTA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Bos taurus 57926 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 57926 R-BTA-352347 https://reactome.org/PathwayBrowser/#/R-BTA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Bos taurus 57926 R-BTA-352354 https://reactome.org/PathwayBrowser/#/R-BTA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Bos taurus 57926 R-BTA-352364 https://reactome.org/PathwayBrowser/#/R-BTA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Bos taurus 57926 R-BTA-352371 https://reactome.org/PathwayBrowser/#/R-BTA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Bos taurus 57926 R-BTA-376200 https://reactome.org/PathwayBrowser/#/R-BTA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Bos taurus 57926 R-BTA-9014627 https://reactome.org/PathwayBrowser/#/R-BTA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Bos taurus 57926 R-CEL-352347 https://reactome.org/PathwayBrowser/#/R-CEL-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Caenorhabditis elegans 57926 R-CEL-352354 https://reactome.org/PathwayBrowser/#/R-CEL-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Caenorhabditis elegans 57926 R-CEL-352364 https://reactome.org/PathwayBrowser/#/R-CEL-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Caenorhabditis elegans 57926 R-CEL-352371 https://reactome.org/PathwayBrowser/#/R-CEL-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Caenorhabditis elegans 57926 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 57926 R-CFA-352108 https://reactome.org/PathwayBrowser/#/R-CFA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Canis familiaris 57926 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 57926 R-CFA-352347 https://reactome.org/PathwayBrowser/#/R-CFA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Canis familiaris 57926 R-CFA-352354 https://reactome.org/PathwayBrowser/#/R-CFA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Canis familiaris 57926 R-CFA-352364 https://reactome.org/PathwayBrowser/#/R-CFA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Canis familiaris 57926 R-CFA-352371 https://reactome.org/PathwayBrowser/#/R-CFA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Canis familiaris 57926 R-CFA-376200 https://reactome.org/PathwayBrowser/#/R-CFA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Canis familiaris 57926 R-CFA-9014627 https://reactome.org/PathwayBrowser/#/R-CFA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Canis familiaris 57926 R-DDI-9014627 https://reactome.org/PathwayBrowser/#/R-DDI-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Dictyostelium discoideum 57926 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 57926 R-DME-352108 https://reactome.org/PathwayBrowser/#/R-DME-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57926 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57926 R-DME-352347 https://reactome.org/PathwayBrowser/#/R-DME-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Drosophila melanogaster 57926 R-DME-352354 https://reactome.org/PathwayBrowser/#/R-DME-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Drosophila melanogaster 57926 R-DME-352364 https://reactome.org/PathwayBrowser/#/R-DME-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Drosophila melanogaster 57926 R-DME-352371 https://reactome.org/PathwayBrowser/#/R-DME-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Drosophila melanogaster 57926 R-DME-376200 https://reactome.org/PathwayBrowser/#/R-DME-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Drosophila melanogaster 57926 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 57926 R-DRE-352108 https://reactome.org/PathwayBrowser/#/R-DRE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Danio rerio 57926 R-DRE-352347 https://reactome.org/PathwayBrowser/#/R-DRE-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Danio rerio 57926 R-DRE-352354 https://reactome.org/PathwayBrowser/#/R-DRE-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Danio rerio 57926 R-DRE-352364 https://reactome.org/PathwayBrowser/#/R-DRE-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Danio rerio 57926 R-DRE-352371 https://reactome.org/PathwayBrowser/#/R-DRE-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Danio rerio 57926 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 57926 R-GGA-352108 https://reactome.org/PathwayBrowser/#/R-GGA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Gallus gallus 57926 R-GGA-352347 https://reactome.org/PathwayBrowser/#/R-GGA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Gallus gallus 57926 R-GGA-352354 https://reactome.org/PathwayBrowser/#/R-GGA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Gallus gallus 57926 R-GGA-352364 https://reactome.org/PathwayBrowser/#/R-GGA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Gallus gallus 57926 R-GGA-352371 https://reactome.org/PathwayBrowser/#/R-GGA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Gallus gallus 57926 R-GGA-9014627 https://reactome.org/PathwayBrowser/#/R-GGA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Gallus gallus 57926 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 57926 R-HSA-352108 https://reactome.org/PathwayBrowser/#/R-HSA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids TAS Homo sapiens 57926 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 57926 R-HSA-352347 https://reactome.org/PathwayBrowser/#/R-HSA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine TAS Homo sapiens 57926 R-HSA-352354 https://reactome.org/PathwayBrowser/#/R-HSA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine TAS Homo sapiens 57926 R-HSA-352364 https://reactome.org/PathwayBrowser/#/R-HSA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine TAS Homo sapiens 57926 R-HSA-352371 https://reactome.org/PathwayBrowser/#/R-HSA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine TAS Homo sapiens 57926 R-HSA-376200 https://reactome.org/PathwayBrowser/#/R-HSA-376200 SLC7A10-mediated uptake of small neutral amino acids TAS Homo sapiens 57926 R-HSA-380002 https://reactome.org/PathwayBrowser/#/R-HSA-380002 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate TAS Homo sapiens 57926 R-HSA-380201 https://reactome.org/PathwayBrowser/#/R-HSA-380201 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate IEA Homo sapiens 57926 R-HSA-6798667 https://reactome.org/PathwayBrowser/#/R-HSA-6798667 TDH tetramer oxidises L-Thr to 2A-3OB TAS Homo sapiens 57926 R-HSA-9014627 https://reactome.org/PathwayBrowser/#/R-HSA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA TAS Homo sapiens 57926 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 57926 R-MMU-352108 https://reactome.org/PathwayBrowser/#/R-MMU-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Mus musculus 57926 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 57926 R-MMU-352347 https://reactome.org/PathwayBrowser/#/R-MMU-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Mus musculus 57926 R-MMU-352354 https://reactome.org/PathwayBrowser/#/R-MMU-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Mus musculus 57926 R-MMU-352364 https://reactome.org/PathwayBrowser/#/R-MMU-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Mus musculus 57926 R-MMU-352371 https://reactome.org/PathwayBrowser/#/R-MMU-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Mus musculus 57926 R-MMU-376200 https://reactome.org/PathwayBrowser/#/R-MMU-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Mus musculus 57926 R-MMU-9014627 https://reactome.org/PathwayBrowser/#/R-MMU-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Mus musculus 57926 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 57926 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 57926 R-RNO-352108 https://reactome.org/PathwayBrowser/#/R-RNO-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Rattus norvegicus 57926 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 57926 R-RNO-352347 https://reactome.org/PathwayBrowser/#/R-RNO-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Rattus norvegicus 57926 R-RNO-352354 https://reactome.org/PathwayBrowser/#/R-RNO-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Rattus norvegicus 57926 R-RNO-352364 https://reactome.org/PathwayBrowser/#/R-RNO-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Rattus norvegicus 57926 R-RNO-352371 https://reactome.org/PathwayBrowser/#/R-RNO-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Rattus norvegicus 57926 R-RNO-376200 https://reactome.org/PathwayBrowser/#/R-RNO-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Rattus norvegicus 57926 R-RNO-9014627 https://reactome.org/PathwayBrowser/#/R-RNO-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Rattus norvegicus 57926 R-SCE-352108 https://reactome.org/PathwayBrowser/#/R-SCE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 57926 R-SCE-9014627 https://reactome.org/PathwayBrowser/#/R-SCE-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Saccharomyces cerevisiae 57926 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 57926 R-SSC-352108 https://reactome.org/PathwayBrowser/#/R-SSC-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Sus scrofa 57926 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 57926 R-SSC-352347 https://reactome.org/PathwayBrowser/#/R-SSC-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Sus scrofa 57926 R-SSC-352354 https://reactome.org/PathwayBrowser/#/R-SSC-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Sus scrofa 57926 R-SSC-352364 https://reactome.org/PathwayBrowser/#/R-SSC-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Sus scrofa 57926 R-SSC-352371 https://reactome.org/PathwayBrowser/#/R-SSC-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Sus scrofa 57926 R-SSC-376200 https://reactome.org/PathwayBrowser/#/R-SSC-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Sus scrofa 57926 R-SSC-9014627 https://reactome.org/PathwayBrowser/#/R-SSC-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Sus scrofa 57926 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 57926 R-XTR-352108 https://reactome.org/PathwayBrowser/#/R-XTR-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57926 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57926 R-XTR-352347 https://reactome.org/PathwayBrowser/#/R-XTR-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Xenopus tropicalis 57926 R-XTR-352354 https://reactome.org/PathwayBrowser/#/R-XTR-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Xenopus tropicalis 57926 R-XTR-352364 https://reactome.org/PathwayBrowser/#/R-XTR-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Xenopus tropicalis 57926 R-XTR-352371 https://reactome.org/PathwayBrowser/#/R-XTR-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Xenopus tropicalis 57926 R-XTR-376200 https://reactome.org/PathwayBrowser/#/R-XTR-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Xenopus tropicalis 57926 R-XTR-9014627 https://reactome.org/PathwayBrowser/#/R-XTR-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Xenopus tropicalis 57930 R-BTA-111742 https://reactome.org/PathwayBrowser/#/R-BTA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 57930 R-BTA-111751 https://reactome.org/PathwayBrowser/#/R-BTA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 57930 R-BTA-111804 https://reactome.org/PathwayBrowser/#/R-BTA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 57930 R-BTA-6806877 https://reactome.org/PathwayBrowser/#/R-BTA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Bos taurus 57930 R-BTA-8850846 https://reactome.org/PathwayBrowser/#/R-BTA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Bos taurus 57930 R-BTA-8850854 https://reactome.org/PathwayBrowser/#/R-BTA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Bos taurus 57930 R-BTA-8851110 https://reactome.org/PathwayBrowser/#/R-BTA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Bos taurus 57930 R-BTA-8851129 https://reactome.org/PathwayBrowser/#/R-BTA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Bos taurus 57930 R-BTA-8866405 https://reactome.org/PathwayBrowser/#/R-BTA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 57930 R-CEL-111742 https://reactome.org/PathwayBrowser/#/R-CEL-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 57930 R-CEL-111751 https://reactome.org/PathwayBrowser/#/R-CEL-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 57930 R-CEL-111804 https://reactome.org/PathwayBrowser/#/R-CEL-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 57930 R-CEL-6806877 https://reactome.org/PathwayBrowser/#/R-CEL-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Caenorhabditis elegans 57930 R-CEL-8866405 https://reactome.org/PathwayBrowser/#/R-CEL-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 57930 R-CFA-111742 https://reactome.org/PathwayBrowser/#/R-CFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 57930 R-CFA-111751 https://reactome.org/PathwayBrowser/#/R-CFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 57930 R-CFA-111804 https://reactome.org/PathwayBrowser/#/R-CFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 57930 R-CFA-6806877 https://reactome.org/PathwayBrowser/#/R-CFA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Canis familiaris 57930 R-CFA-8850846 https://reactome.org/PathwayBrowser/#/R-CFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Canis familiaris 57930 R-CFA-8850854 https://reactome.org/PathwayBrowser/#/R-CFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Canis familiaris 57930 R-CFA-8851110 https://reactome.org/PathwayBrowser/#/R-CFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Canis familiaris 57930 R-CFA-8851129 https://reactome.org/PathwayBrowser/#/R-CFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Canis familiaris 57930 R-CFA-8866405 https://reactome.org/PathwayBrowser/#/R-CFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 57930 R-DDI-111751 https://reactome.org/PathwayBrowser/#/R-DDI-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 57930 R-DDI-111804 https://reactome.org/PathwayBrowser/#/R-DDI-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 57930 R-DDI-6806877 https://reactome.org/PathwayBrowser/#/R-DDI-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Dictyostelium discoideum 57930 R-DME-111751 https://reactome.org/PathwayBrowser/#/R-DME-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 57930 R-DME-111804 https://reactome.org/PathwayBrowser/#/R-DME-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 57930 R-DME-6806877 https://reactome.org/PathwayBrowser/#/R-DME-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Drosophila melanogaster 57930 R-DRE-111742 https://reactome.org/PathwayBrowser/#/R-DRE-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 57930 R-DRE-111751 https://reactome.org/PathwayBrowser/#/R-DRE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 57930 R-DRE-111804 https://reactome.org/PathwayBrowser/#/R-DRE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 57930 R-DRE-6806877 https://reactome.org/PathwayBrowser/#/R-DRE-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Danio rerio 57930 R-DRE-8866405 https://reactome.org/PathwayBrowser/#/R-DRE-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 57930 R-GGA-6806877 https://reactome.org/PathwayBrowser/#/R-GGA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Gallus gallus 57930 R-GGA-8850846 https://reactome.org/PathwayBrowser/#/R-GGA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Gallus gallus 57930 R-GGA-8850854 https://reactome.org/PathwayBrowser/#/R-GGA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Gallus gallus 57930 R-GGA-8851110 https://reactome.org/PathwayBrowser/#/R-GGA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Gallus gallus 57930 R-GGA-8851129 https://reactome.org/PathwayBrowser/#/R-GGA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Gallus gallus 57930 R-HSA-111742 https://reactome.org/PathwayBrowser/#/R-HSA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 57930 R-HSA-111751 https://reactome.org/PathwayBrowser/#/R-HSA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 57930 R-HSA-111804 https://reactome.org/PathwayBrowser/#/R-HSA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 57930 R-HSA-6806877 https://reactome.org/PathwayBrowser/#/R-HSA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs TAS Homo sapiens 57930 R-HSA-8850846 https://reactome.org/PathwayBrowser/#/R-HSA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates TAS Homo sapiens 57930 R-HSA-8850854 https://reactome.org/PathwayBrowser/#/R-HSA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates TAS Homo sapiens 57930 R-HSA-8851110 https://reactome.org/PathwayBrowser/#/R-HSA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates TAS Homo sapiens 57930 R-HSA-8851129 https://reactome.org/PathwayBrowser/#/R-HSA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates TAS Homo sapiens 57930 R-HSA-8866405 https://reactome.org/PathwayBrowser/#/R-HSA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 57930 R-HSA-9683669 https://reactome.org/PathwayBrowser/#/R-HSA-9683669 E protein gets N-glycosylated TAS Homo sapiens 57930 R-HSA-9683751 https://reactome.org/PathwayBrowser/#/R-HSA-9683751 M protein gets N-glycosylated TAS Homo sapiens 57930 R-HSA-9683755 https://reactome.org/PathwayBrowser/#/R-HSA-9683755 Spike protein gets N-glycosylated TAS Homo sapiens 57930 R-HSA-9684261 https://reactome.org/PathwayBrowser/#/R-HSA-9684261 nsp4 is glycosylated TAS Homo sapiens 57930 R-HSA-9684275 https://reactome.org/PathwayBrowser/#/R-HSA-9684275 nsp3-4 is glycosylated TAS Homo sapiens 57930 R-HSA-9684290 https://reactome.org/PathwayBrowser/#/R-HSA-9684290 nsp3 is glycosylated TAS Homo sapiens 57930 R-HSA-9694331 https://reactome.org/PathwayBrowser/#/R-HSA-9694331 nsp3-4 is glycosylated IEA Homo sapiens 57930 R-HSA-9694389 https://reactome.org/PathwayBrowser/#/R-HSA-9694389 nsp3 is glycosylated IEA Homo sapiens 57930 R-HSA-9694525 https://reactome.org/PathwayBrowser/#/R-HSA-9694525 M protein gets N-glycosylated IEA Homo sapiens 57930 R-HSA-9694611 https://reactome.org/PathwayBrowser/#/R-HSA-9694611 nsp4 is glycosylated IEA Homo sapiens 57930 R-HSA-9694790 https://reactome.org/PathwayBrowser/#/R-HSA-9694790 E protein gets N-glycosylated IEA Homo sapiens 57930 R-MMU-111742 https://reactome.org/PathwayBrowser/#/R-MMU-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 57930 R-MMU-111751 https://reactome.org/PathwayBrowser/#/R-MMU-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 57930 R-MMU-111804 https://reactome.org/PathwayBrowser/#/R-MMU-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 57930 R-MMU-6806877 https://reactome.org/PathwayBrowser/#/R-MMU-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Mus musculus 57930 R-MMU-8850846 https://reactome.org/PathwayBrowser/#/R-MMU-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Mus musculus 57930 R-MMU-8850854 https://reactome.org/PathwayBrowser/#/R-MMU-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Mus musculus 57930 R-MMU-8851110 https://reactome.org/PathwayBrowser/#/R-MMU-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Mus musculus 57930 R-MMU-8851129 https://reactome.org/PathwayBrowser/#/R-MMU-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Mus musculus 57930 R-MMU-8866405 https://reactome.org/PathwayBrowser/#/R-MMU-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 57930 R-PFA-111742 https://reactome.org/PathwayBrowser/#/R-PFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 57930 R-PFA-111751 https://reactome.org/PathwayBrowser/#/R-PFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 57930 R-PFA-111804 https://reactome.org/PathwayBrowser/#/R-PFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 57930 R-PFA-6806877 https://reactome.org/PathwayBrowser/#/R-PFA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Plasmodium falciparum 57930 R-PFA-8850846 https://reactome.org/PathwayBrowser/#/R-PFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 57930 R-PFA-8850854 https://reactome.org/PathwayBrowser/#/R-PFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 57930 R-PFA-8851110 https://reactome.org/PathwayBrowser/#/R-PFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 57930 R-PFA-8851129 https://reactome.org/PathwayBrowser/#/R-PFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 57930 R-PFA-8866405 https://reactome.org/PathwayBrowser/#/R-PFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 57930 R-RNO-111742 https://reactome.org/PathwayBrowser/#/R-RNO-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 57930 R-RNO-111751 https://reactome.org/PathwayBrowser/#/R-RNO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 57930 R-RNO-111804 https://reactome.org/PathwayBrowser/#/R-RNO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 57930 R-RNO-6806877 https://reactome.org/PathwayBrowser/#/R-RNO-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Rattus norvegicus 57930 R-RNO-8850846 https://reactome.org/PathwayBrowser/#/R-RNO-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 57930 R-RNO-8850854 https://reactome.org/PathwayBrowser/#/R-RNO-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 57930 R-RNO-8851110 https://reactome.org/PathwayBrowser/#/R-RNO-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 57930 R-RNO-8851129 https://reactome.org/PathwayBrowser/#/R-RNO-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 57930 R-RNO-8866405 https://reactome.org/PathwayBrowser/#/R-RNO-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 57930 R-SCE-111751 https://reactome.org/PathwayBrowser/#/R-SCE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 57930 R-SCE-111804 https://reactome.org/PathwayBrowser/#/R-SCE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 57930 R-SCE-6806877 https://reactome.org/PathwayBrowser/#/R-SCE-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Saccharomyces cerevisiae 57930 R-SPO-111751 https://reactome.org/PathwayBrowser/#/R-SPO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 57930 R-SPO-111804 https://reactome.org/PathwayBrowser/#/R-SPO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 57930 R-SPO-6806877 https://reactome.org/PathwayBrowser/#/R-SPO-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Schizosaccharomyces pombe 57930 R-SSC-111742 https://reactome.org/PathwayBrowser/#/R-SSC-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 57930 R-SSC-111751 https://reactome.org/PathwayBrowser/#/R-SSC-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 57930 R-SSC-111804 https://reactome.org/PathwayBrowser/#/R-SSC-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 57930 R-SSC-6806877 https://reactome.org/PathwayBrowser/#/R-SSC-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Sus scrofa 57930 R-SSC-8850846 https://reactome.org/PathwayBrowser/#/R-SSC-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Sus scrofa 57930 R-SSC-8850854 https://reactome.org/PathwayBrowser/#/R-SSC-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Sus scrofa 57930 R-SSC-8851110 https://reactome.org/PathwayBrowser/#/R-SSC-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Sus scrofa 57930 R-SSC-8851129 https://reactome.org/PathwayBrowser/#/R-SSC-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Sus scrofa 57930 R-SSC-8866405 https://reactome.org/PathwayBrowser/#/R-SSC-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 57930 R-XTR-111742 https://reactome.org/PathwayBrowser/#/R-XTR-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 57930 R-XTR-6806877 https://reactome.org/PathwayBrowser/#/R-XTR-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Xenopus tropicalis 57930 R-XTR-8850846 https://reactome.org/PathwayBrowser/#/R-XTR-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 57930 R-XTR-8850854 https://reactome.org/PathwayBrowser/#/R-XTR-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 57930 R-XTR-8851110 https://reactome.org/PathwayBrowser/#/R-XTR-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 57930 R-XTR-8851129 https://reactome.org/PathwayBrowser/#/R-XTR-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 57930 R-XTR-8866405 https://reactome.org/PathwayBrowser/#/R-XTR-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 57939 R-BTA-428681 https://reactome.org/PathwayBrowser/#/R-BTA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Bos taurus 57939 R-CEL-428681 https://reactome.org/PathwayBrowser/#/R-CEL-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Caenorhabditis elegans 57939 R-CFA-428681 https://reactome.org/PathwayBrowser/#/R-CFA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Canis familiaris 57939 R-DDI-428681 https://reactome.org/PathwayBrowser/#/R-DDI-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Dictyostelium discoideum 57939 R-DME-428681 https://reactome.org/PathwayBrowser/#/R-DME-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Drosophila melanogaster 57939 R-GGA-428681 https://reactome.org/PathwayBrowser/#/R-GGA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Gallus gallus 57939 R-GGA-433606 https://reactome.org/PathwayBrowser/#/R-GGA-433606 sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP IEA Gallus gallus 57939 R-HSA-428681 https://reactome.org/PathwayBrowser/#/R-HSA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates TAS Homo sapiens 57939 R-MMU-428681 https://reactome.org/PathwayBrowser/#/R-MMU-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Mus musculus 57939 R-RNO-428681 https://reactome.org/PathwayBrowser/#/R-RNO-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Rattus norvegicus 57939 R-SCE-428681 https://reactome.org/PathwayBrowser/#/R-SCE-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Saccharomyces cerevisiae 57939 R-SSC-428681 https://reactome.org/PathwayBrowser/#/R-SSC-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Sus scrofa 57939 R-XTR-428681 https://reactome.org/PathwayBrowser/#/R-XTR-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Xenopus tropicalis 57945 R-BTA-109343 https://reactome.org/PathwayBrowser/#/R-BTA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Bos taurus 57945 R-BTA-1614362 https://reactome.org/PathwayBrowser/#/R-BTA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Bos taurus 57945 R-BTA-163217 https://reactome.org/PathwayBrowser/#/R-BTA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Bos taurus 57945 R-BTA-173597 https://reactome.org/PathwayBrowser/#/R-BTA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Bos taurus 57945 R-BTA-192097 https://reactome.org/PathwayBrowser/#/R-BTA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Bos taurus 57945 R-BTA-193073 https://reactome.org/PathwayBrowser/#/R-BTA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Bos taurus 57945 R-BTA-193455 https://reactome.org/PathwayBrowser/#/R-BTA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 57945 R-BTA-193508 https://reactome.org/PathwayBrowser/#/R-BTA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 57945 R-BTA-193789 https://reactome.org/PathwayBrowser/#/R-BTA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Bos taurus 57945 R-BTA-193816 https://reactome.org/PathwayBrowser/#/R-BTA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Bos taurus 57945 R-BTA-194642 https://reactome.org/PathwayBrowser/#/R-BTA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Bos taurus 57945 R-BTA-194718 https://reactome.org/PathwayBrowser/#/R-BTA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Bos taurus 57945 R-BTA-196350 https://reactome.org/PathwayBrowser/#/R-BTA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Bos taurus 57945 R-BTA-196372 https://reactome.org/PathwayBrowser/#/R-BTA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Bos taurus 57945 R-BTA-198824 https://reactome.org/PathwayBrowser/#/R-BTA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Bos taurus 57945 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 57945 R-BTA-2046084 https://reactome.org/PathwayBrowser/#/R-BTA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Bos taurus 57945 R-BTA-2046089 https://reactome.org/PathwayBrowser/#/R-BTA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Bos taurus 57945 R-BTA-2046092 https://reactome.org/PathwayBrowser/#/R-BTA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Bos taurus 57945 R-BTA-2046096 https://reactome.org/PathwayBrowser/#/R-BTA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Bos taurus 57945 R-BTA-2046097 https://reactome.org/PathwayBrowser/#/R-BTA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 57945 R-BTA-204617 https://reactome.org/PathwayBrowser/#/R-BTA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Bos taurus 57945 R-BTA-204647 https://reactome.org/PathwayBrowser/#/R-BTA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Bos taurus 57945 R-BTA-204662 https://reactome.org/PathwayBrowser/#/R-BTA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Bos taurus 57945 R-BTA-2161779 https://reactome.org/PathwayBrowser/#/R-BTA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Bos taurus 57945 R-BTA-2162078 https://reactome.org/PathwayBrowser/#/R-BTA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Bos taurus 57945 R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 57945 R-BTA-2454081 https://reactome.org/PathwayBrowser/#/R-BTA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Bos taurus 57945 R-BTA-380608 https://reactome.org/PathwayBrowser/#/R-BTA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Bos taurus 57945 R-BTA-389609 https://reactome.org/PathwayBrowser/#/R-BTA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Bos taurus 57945 R-BTA-389995 https://reactome.org/PathwayBrowser/#/R-BTA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Bos taurus 57945 R-BTA-390251 https://reactome.org/PathwayBrowser/#/R-BTA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 57945 R-BTA-450971 https://reactome.org/PathwayBrowser/#/R-BTA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Bos taurus 57945 R-BTA-508369 https://reactome.org/PathwayBrowser/#/R-BTA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Bos taurus 57945 R-BTA-508473 https://reactome.org/PathwayBrowser/#/R-BTA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Bos taurus 57945 R-BTA-5362518 https://reactome.org/PathwayBrowser/#/R-BTA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Bos taurus 57945 R-BTA-5362522 https://reactome.org/PathwayBrowser/#/R-BTA-5362522 ALDHs oxidise atRAL to atRA IEA Bos taurus 57945 R-BTA-5362564 https://reactome.org/PathwayBrowser/#/R-BTA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Bos taurus 57945 R-BTA-5362721 https://reactome.org/PathwayBrowser/#/R-BTA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Bos taurus 57945 R-BTA-5652195 https://reactome.org/PathwayBrowser/#/R-BTA-5652195 SORD oxidizes D-sorbitol to Fru IEA Bos taurus 57945 R-BTA-5661290 https://reactome.org/PathwayBrowser/#/R-BTA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Bos taurus 57945 R-BTA-5662471 https://reactome.org/PathwayBrowser/#/R-BTA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Bos taurus 57945 R-BTA-5692237 https://reactome.org/PathwayBrowser/#/R-BTA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Bos taurus 57945 R-BTA-5692261 https://reactome.org/PathwayBrowser/#/R-BTA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Bos taurus 57945 R-BTA-5694018 https://reactome.org/PathwayBrowser/#/R-BTA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Bos taurus 57945 R-BTA-5696080 https://reactome.org/PathwayBrowser/#/R-BTA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Bos taurus 57945 R-BTA-5696091 https://reactome.org/PathwayBrowser/#/R-BTA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Bos taurus 57945 R-BTA-5696101 https://reactome.org/PathwayBrowser/#/R-BTA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Bos taurus 57945 R-BTA-5696457 https://reactome.org/PathwayBrowser/#/R-BTA-5696457 BDH2 dehydrogenates 3HBA IEA Bos taurus 57945 R-BTA-6783939 https://reactome.org/PathwayBrowser/#/R-BTA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 57945 R-BTA-6784399 https://reactome.org/PathwayBrowser/#/R-BTA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Bos taurus 57945 R-BTA-6797955 https://reactome.org/PathwayBrowser/#/R-BTA-6797955 ALDH7A1 oxidises BETALD to BET IEA Bos taurus 57945 R-BTA-6801328 https://reactome.org/PathwayBrowser/#/R-BTA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Bos taurus 57945 R-BTA-6806831 https://reactome.org/PathwayBrowser/#/R-BTA-6806831 CYB5Rs reduce MetHb to HbA IEA Bos taurus 57945 R-BTA-6808464 https://reactome.org/PathwayBrowser/#/R-BTA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Bos taurus 57945 R-BTA-6809264 https://reactome.org/PathwayBrowser/#/R-BTA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 57945 R-BTA-6809287 https://reactome.org/PathwayBrowser/#/R-BTA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Bos taurus 57945 R-BTA-6813749 https://reactome.org/PathwayBrowser/#/R-BTA-6813749 ALDH1A1 oxidises GA to DGA IEA Bos taurus 57945 R-BTA-70449 https://reactome.org/PathwayBrowser/#/R-BTA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Bos taurus 57945 R-BTA-70482 https://reactome.org/PathwayBrowser/#/R-BTA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Bos taurus 57945 R-BTA-70510 https://reactome.org/PathwayBrowser/#/R-BTA-70510 LDH tetramer oxidises LACT to PYR IEA Bos taurus 57945 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Bos taurus 57945 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Bos taurus 57945 R-BTA-70664 https://reactome.org/PathwayBrowser/#/R-BTA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 57945 R-BTA-70679 https://reactome.org/PathwayBrowser/#/R-BTA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Bos taurus 57945 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 57945 R-BTA-70837 https://reactome.org/PathwayBrowser/#/R-BTA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Bos taurus 57945 R-BTA-70885 https://reactome.org/PathwayBrowser/#/R-BTA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Bos taurus 57945 R-BTA-70893 https://reactome.org/PathwayBrowser/#/R-BTA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Bos taurus 57945 R-BTA-70940 https://reactome.org/PathwayBrowser/#/R-BTA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Bos taurus 57945 R-BTA-70941 https://reactome.org/PathwayBrowser/#/R-BTA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Bos taurus 57945 R-BTA-70967 https://reactome.org/PathwayBrowser/#/R-BTA-70967 IDH3 complex decarboxylates isocitrate IEA Bos taurus 57945 R-BTA-70979 https://reactome.org/PathwayBrowser/#/R-BTA-70979 MDH2 dimer dehydrogenates MAL IEA Bos taurus 57945 R-BTA-71037 https://reactome.org/PathwayBrowser/#/R-BTA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Bos taurus 57945 R-BTA-71130 https://reactome.org/PathwayBrowser/#/R-BTA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Bos taurus 57945 R-BTA-71260 https://reactome.org/PathwayBrowser/#/R-BTA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Bos taurus 57945 R-BTA-71401 https://reactome.org/PathwayBrowser/#/R-BTA-71401 OGDH dimer decarboxylates 2-OG IEA Bos taurus 57945 R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 57945 R-BTA-71707 https://reactome.org/PathwayBrowser/#/R-BTA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Bos taurus 57945 R-BTA-71723 https://reactome.org/PathwayBrowser/#/R-BTA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Bos taurus 57945 R-BTA-71849 https://reactome.org/PathwayBrowser/#/R-BTA-71849 LDH tetramer reduces PYR to LACT IEA Bos taurus 57945 R-BTA-73794 https://reactome.org/PathwayBrowser/#/R-BTA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Bos taurus 57945 R-BTA-73912 https://reactome.org/PathwayBrowser/#/R-BTA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Bos taurus 57945 R-BTA-73920 https://reactome.org/PathwayBrowser/#/R-BTA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Bos taurus 57945 R-BTA-75889 https://reactome.org/PathwayBrowser/#/R-BTA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Bos taurus 57945 R-BTA-77254 https://reactome.org/PathwayBrowser/#/R-BTA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Bos taurus 57945 R-BTA-77283 https://reactome.org/PathwayBrowser/#/R-BTA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Bos taurus 57945 R-BTA-77303 https://reactome.org/PathwayBrowser/#/R-BTA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Bos taurus 57945 R-BTA-77312 https://reactome.org/PathwayBrowser/#/R-BTA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Bos taurus 57945 R-BTA-77323 https://reactome.org/PathwayBrowser/#/R-BTA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Bos taurus 57945 R-BTA-77331 https://reactome.org/PathwayBrowser/#/R-BTA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Bos taurus 57945 R-BTA-77342 https://reactome.org/PathwayBrowser/#/R-BTA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Bos taurus 57945 R-BTA-888548 https://reactome.org/PathwayBrowser/#/R-BTA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Bos taurus 57945 R-BTA-8936442 https://reactome.org/PathwayBrowser/#/R-BTA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Bos taurus 57945 R-BTA-9012268 https://reactome.org/PathwayBrowser/#/R-BTA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Bos taurus 57945 R-BTA-9023968 https://reactome.org/PathwayBrowser/#/R-BTA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Bos taurus 57945 R-BTA-9024766 https://reactome.org/PathwayBrowser/#/R-BTA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Bos taurus 57945 R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 57945 R-BTA-9727349 https://reactome.org/PathwayBrowser/#/R-BTA-9727349 XDH dehydrogenates xanthine to form urate IEA Bos taurus 57945 R-BTA-9748945 https://reactome.org/PathwayBrowser/#/R-BTA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Bos taurus 57945 R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 57945 R-BTA-9759549 https://reactome.org/PathwayBrowser/#/R-BTA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Bos taurus 57945 R-BTA-977348 https://reactome.org/PathwayBrowser/#/R-BTA-977348 PHGDH tetramer dehydrogenates 3PG IEA Bos taurus 57945 R-BTA-9853499 https://reactome.org/PathwayBrowser/#/R-BTA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 57945 R-BTA-9856871 https://reactome.org/PathwayBrowser/#/R-BTA-9856871 MDH1 reduces OA IEA Bos taurus 57945 R-BTA-9861616 https://reactome.org/PathwayBrowser/#/R-BTA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 57945 R-CEL-109343 https://reactome.org/PathwayBrowser/#/R-CEL-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Caenorhabditis elegans 57945 R-CEL-173597 https://reactome.org/PathwayBrowser/#/R-CEL-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Caenorhabditis elegans 57945 R-CEL-193455 https://reactome.org/PathwayBrowser/#/R-CEL-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 57945 R-CEL-193508 https://reactome.org/PathwayBrowser/#/R-CEL-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 57945 R-CEL-194642 https://reactome.org/PathwayBrowser/#/R-CEL-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Caenorhabditis elegans 57945 R-CEL-194718 https://reactome.org/PathwayBrowser/#/R-CEL-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Caenorhabditis elegans 57945 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 57945 R-CEL-2046084 https://reactome.org/PathwayBrowser/#/R-CEL-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Caenorhabditis elegans 57945 R-CEL-2046089 https://reactome.org/PathwayBrowser/#/R-CEL-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Caenorhabditis elegans 57945 R-CEL-2046092 https://reactome.org/PathwayBrowser/#/R-CEL-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Caenorhabditis elegans 57945 R-CEL-2046096 https://reactome.org/PathwayBrowser/#/R-CEL-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Caenorhabditis elegans 57945 R-CEL-2046097 https://reactome.org/PathwayBrowser/#/R-CEL-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Caenorhabditis elegans 57945 R-CEL-204617 https://reactome.org/PathwayBrowser/#/R-CEL-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Caenorhabditis elegans 57945 R-CEL-204647 https://reactome.org/PathwayBrowser/#/R-CEL-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Caenorhabditis elegans 57945 R-CEL-204662 https://reactome.org/PathwayBrowser/#/R-CEL-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Caenorhabditis elegans 57945 R-CEL-2162078 https://reactome.org/PathwayBrowser/#/R-CEL-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Caenorhabditis elegans 57945 R-CEL-380608 https://reactome.org/PathwayBrowser/#/R-CEL-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Caenorhabditis elegans 57945 R-CEL-389609 https://reactome.org/PathwayBrowser/#/R-CEL-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Caenorhabditis elegans 57945 R-CEL-389995 https://reactome.org/PathwayBrowser/#/R-CEL-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Caenorhabditis elegans 57945 R-CEL-390251 https://reactome.org/PathwayBrowser/#/R-CEL-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 57945 R-CEL-450971 https://reactome.org/PathwayBrowser/#/R-CEL-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Caenorhabditis elegans 57945 R-CEL-508369 https://reactome.org/PathwayBrowser/#/R-CEL-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Caenorhabditis elegans 57945 R-CEL-508473 https://reactome.org/PathwayBrowser/#/R-CEL-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Caenorhabditis elegans 57945 R-CEL-5362518 https://reactome.org/PathwayBrowser/#/R-CEL-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Caenorhabditis elegans 57945 R-CEL-5362522 https://reactome.org/PathwayBrowser/#/R-CEL-5362522 ALDHs oxidise atRAL to atRA IEA Caenorhabditis elegans 57945 R-CEL-5362564 https://reactome.org/PathwayBrowser/#/R-CEL-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Caenorhabditis elegans 57945 R-CEL-5362721 https://reactome.org/PathwayBrowser/#/R-CEL-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Caenorhabditis elegans 57945 R-CEL-5652195 https://reactome.org/PathwayBrowser/#/R-CEL-5652195 SORD oxidizes D-sorbitol to Fru IEA Caenorhabditis elegans 57945 R-CEL-5661290 https://reactome.org/PathwayBrowser/#/R-CEL-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Caenorhabditis elegans 57945 R-CEL-5662471 https://reactome.org/PathwayBrowser/#/R-CEL-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Caenorhabditis elegans 57945 R-CEL-5692237 https://reactome.org/PathwayBrowser/#/R-CEL-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Caenorhabditis elegans 57945 R-CEL-5692261 https://reactome.org/PathwayBrowser/#/R-CEL-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Caenorhabditis elegans 57945 R-CEL-5694018 https://reactome.org/PathwayBrowser/#/R-CEL-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Caenorhabditis elegans 57945 R-CEL-5696080 https://reactome.org/PathwayBrowser/#/R-CEL-5696080 ALDH3B1 oxidises HXAL to PALM IEA Caenorhabditis elegans 57945 R-CEL-5696091 https://reactome.org/PathwayBrowser/#/R-CEL-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Caenorhabditis elegans 57945 R-CEL-5696101 https://reactome.org/PathwayBrowser/#/R-CEL-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Caenorhabditis elegans 57945 R-CEL-6783939 https://reactome.org/PathwayBrowser/#/R-CEL-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 57945 R-CEL-6797955 https://reactome.org/PathwayBrowser/#/R-CEL-6797955 ALDH7A1 oxidises BETALD to BET IEA Caenorhabditis elegans 57945 R-CEL-6807826 https://reactome.org/PathwayBrowser/#/R-CEL-6807826 LDHAL6B reduces PYR to LACT IEA Caenorhabditis elegans 57945 R-CEL-6808464 https://reactome.org/PathwayBrowser/#/R-CEL-6808464 ALDH3B2 oxidises HXAL to PALM IEA Caenorhabditis elegans 57945 R-CEL-6809264 https://reactome.org/PathwayBrowser/#/R-CEL-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 57945 R-CEL-6809287 https://reactome.org/PathwayBrowser/#/R-CEL-6809287 NUDT12 hydrolyses NADH to NMNH IEA Caenorhabditis elegans 57945 R-CEL-6813749 https://reactome.org/PathwayBrowser/#/R-CEL-6813749 ALDH1A1 oxidises GA to DGA IEA Caenorhabditis elegans 57945 R-CEL-70449 https://reactome.org/PathwayBrowser/#/R-CEL-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Caenorhabditis elegans 57945 R-CEL-70482 https://reactome.org/PathwayBrowser/#/R-CEL-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Caenorhabditis elegans 57945 R-CEL-70510 https://reactome.org/PathwayBrowser/#/R-CEL-70510 LDH tetramer oxidises LACT to PYR IEA Caenorhabditis elegans 57945 R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Caenorhabditis elegans 57945 R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Caenorhabditis elegans 57945 R-CEL-70664 https://reactome.org/PathwayBrowser/#/R-CEL-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 57945 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 57945 R-CEL-70837 https://reactome.org/PathwayBrowser/#/R-CEL-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Caenorhabditis elegans 57945 R-CEL-70885 https://reactome.org/PathwayBrowser/#/R-CEL-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Caenorhabditis elegans 57945 R-CEL-70893 https://reactome.org/PathwayBrowser/#/R-CEL-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 57945 R-CEL-70940 https://reactome.org/PathwayBrowser/#/R-CEL-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Caenorhabditis elegans 57945 R-CEL-70941 https://reactome.org/PathwayBrowser/#/R-CEL-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Caenorhabditis elegans 57945 R-CEL-70967 https://reactome.org/PathwayBrowser/#/R-CEL-70967 IDH3 complex decarboxylates isocitrate IEA Caenorhabditis elegans 57945 R-CEL-70979 https://reactome.org/PathwayBrowser/#/R-CEL-70979 MDH2 dimer dehydrogenates MAL IEA Caenorhabditis elegans 57945 R-CEL-71037 https://reactome.org/PathwayBrowser/#/R-CEL-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 57945 R-CEL-71130 https://reactome.org/PathwayBrowser/#/R-CEL-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Caenorhabditis elegans 57945 R-CEL-71260 https://reactome.org/PathwayBrowser/#/R-CEL-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Caenorhabditis elegans 57945 R-CEL-71401 https://reactome.org/PathwayBrowser/#/R-CEL-71401 OGDH dimer decarboxylates 2-OG IEA Caenorhabditis elegans 57945 R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 57945 R-CEL-71707 https://reactome.org/PathwayBrowser/#/R-CEL-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Caenorhabditis elegans 57945 R-CEL-71723 https://reactome.org/PathwayBrowser/#/R-CEL-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Caenorhabditis elegans 57945 R-CEL-71849 https://reactome.org/PathwayBrowser/#/R-CEL-71849 LDH tetramer reduces PYR to LACT IEA Caenorhabditis elegans 57945 R-CEL-73794 https://reactome.org/PathwayBrowser/#/R-CEL-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Caenorhabditis elegans 57945 R-CEL-75889 https://reactome.org/PathwayBrowser/#/R-CEL-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Caenorhabditis elegans 57945 R-CEL-77254 https://reactome.org/PathwayBrowser/#/R-CEL-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 57945 R-CEL-77283 https://reactome.org/PathwayBrowser/#/R-CEL-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 57945 R-CEL-77303 https://reactome.org/PathwayBrowser/#/R-CEL-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Caenorhabditis elegans 57945 R-CEL-77312 https://reactome.org/PathwayBrowser/#/R-CEL-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Caenorhabditis elegans 57945 R-CEL-77323 https://reactome.org/PathwayBrowser/#/R-CEL-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Caenorhabditis elegans 57945 R-CEL-77331 https://reactome.org/PathwayBrowser/#/R-CEL-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Caenorhabditis elegans 57945 R-CEL-77342 https://reactome.org/PathwayBrowser/#/R-CEL-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 57945 R-CEL-888548 https://reactome.org/PathwayBrowser/#/R-CEL-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Caenorhabditis elegans 57945 R-CEL-8936442 https://reactome.org/PathwayBrowser/#/R-CEL-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Caenorhabditis elegans 57945 R-CEL-9012268 https://reactome.org/PathwayBrowser/#/R-CEL-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 57945 R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 57945 R-CEL-9727349 https://reactome.org/PathwayBrowser/#/R-CEL-9727349 XDH dehydrogenates xanthine to form urate IEA Caenorhabditis elegans 57945 R-CEL-9748945 https://reactome.org/PathwayBrowser/#/R-CEL-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Caenorhabditis elegans 57945 R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 57945 R-CEL-9759549 https://reactome.org/PathwayBrowser/#/R-CEL-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Caenorhabditis elegans 57945 R-CEL-977348 https://reactome.org/PathwayBrowser/#/R-CEL-977348 PHGDH tetramer dehydrogenates 3PG IEA Caenorhabditis elegans 57945 R-CEL-9853499 https://reactome.org/PathwayBrowser/#/R-CEL-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 57945 R-CEL-9856871 https://reactome.org/PathwayBrowser/#/R-CEL-9856871 MDH1 reduces OA IEA Caenorhabditis elegans 57945 R-CEL-9861616 https://reactome.org/PathwayBrowser/#/R-CEL-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 57945 R-CFA-109343 https://reactome.org/PathwayBrowser/#/R-CFA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Canis familiaris 57945 R-CFA-1614362 https://reactome.org/PathwayBrowser/#/R-CFA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Canis familiaris 57945 R-CFA-163217 https://reactome.org/PathwayBrowser/#/R-CFA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Canis familiaris 57945 R-CFA-173597 https://reactome.org/PathwayBrowser/#/R-CFA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Canis familiaris 57945 R-CFA-192097 https://reactome.org/PathwayBrowser/#/R-CFA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Canis familiaris 57945 R-CFA-193073 https://reactome.org/PathwayBrowser/#/R-CFA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Canis familiaris 57945 R-CFA-193455 https://reactome.org/PathwayBrowser/#/R-CFA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 57945 R-CFA-193508 https://reactome.org/PathwayBrowser/#/R-CFA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 57945 R-CFA-193789 https://reactome.org/PathwayBrowser/#/R-CFA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Canis familiaris 57945 R-CFA-193816 https://reactome.org/PathwayBrowser/#/R-CFA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Canis familiaris 57945 R-CFA-194642 https://reactome.org/PathwayBrowser/#/R-CFA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Canis familiaris 57945 R-CFA-194718 https://reactome.org/PathwayBrowser/#/R-CFA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Canis familiaris 57945 R-CFA-196350 https://reactome.org/PathwayBrowser/#/R-CFA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Canis familiaris 57945 R-CFA-196372 https://reactome.org/PathwayBrowser/#/R-CFA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Canis familiaris 57945 R-CFA-198824 https://reactome.org/PathwayBrowser/#/R-CFA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Canis familiaris 57945 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 57945 R-CFA-2046084 https://reactome.org/PathwayBrowser/#/R-CFA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Canis familiaris 57945 R-CFA-2046089 https://reactome.org/PathwayBrowser/#/R-CFA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Canis familiaris 57945 R-CFA-2046092 https://reactome.org/PathwayBrowser/#/R-CFA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Canis familiaris 57945 R-CFA-2046096 https://reactome.org/PathwayBrowser/#/R-CFA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Canis familiaris 57945 R-CFA-2046097 https://reactome.org/PathwayBrowser/#/R-CFA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 57945 R-CFA-204617 https://reactome.org/PathwayBrowser/#/R-CFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Canis familiaris 57945 R-CFA-204647 https://reactome.org/PathwayBrowser/#/R-CFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Canis familiaris 57945 R-CFA-204662 https://reactome.org/PathwayBrowser/#/R-CFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Canis familiaris 57945 R-CFA-2161779 https://reactome.org/PathwayBrowser/#/R-CFA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Canis familiaris 57945 R-CFA-2162078 https://reactome.org/PathwayBrowser/#/R-CFA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Canis familiaris 57945 R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 57945 R-CFA-2454081 https://reactome.org/PathwayBrowser/#/R-CFA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Canis familiaris 57945 R-CFA-380608 https://reactome.org/PathwayBrowser/#/R-CFA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Canis familiaris 57945 R-CFA-389609 https://reactome.org/PathwayBrowser/#/R-CFA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Canis familiaris 57945 R-CFA-389995 https://reactome.org/PathwayBrowser/#/R-CFA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Canis familiaris 57945 R-CFA-390251 https://reactome.org/PathwayBrowser/#/R-CFA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 57945 R-CFA-450971 https://reactome.org/PathwayBrowser/#/R-CFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Canis familiaris 57945 R-CFA-508369 https://reactome.org/PathwayBrowser/#/R-CFA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Canis familiaris 57945 R-CFA-508473 https://reactome.org/PathwayBrowser/#/R-CFA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Canis familiaris 57945 R-CFA-5362518 https://reactome.org/PathwayBrowser/#/R-CFA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Canis familiaris 57945 R-CFA-5362522 https://reactome.org/PathwayBrowser/#/R-CFA-5362522 ALDHs oxidise atRAL to atRA IEA Canis familiaris 57945 R-CFA-5362564 https://reactome.org/PathwayBrowser/#/R-CFA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Canis familiaris 57945 R-CFA-5362721 https://reactome.org/PathwayBrowser/#/R-CFA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Canis familiaris 57945 R-CFA-5652195 https://reactome.org/PathwayBrowser/#/R-CFA-5652195 SORD oxidizes D-sorbitol to Fru IEA Canis familiaris 57945 R-CFA-5661290 https://reactome.org/PathwayBrowser/#/R-CFA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Canis familiaris 57945 R-CFA-5662471 https://reactome.org/PathwayBrowser/#/R-CFA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Canis familiaris 57945 R-CFA-5692237 https://reactome.org/PathwayBrowser/#/R-CFA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Canis familiaris 57945 R-CFA-5692261 https://reactome.org/PathwayBrowser/#/R-CFA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Canis familiaris 57945 R-CFA-5694018 https://reactome.org/PathwayBrowser/#/R-CFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Canis familiaris 57945 R-CFA-5696080 https://reactome.org/PathwayBrowser/#/R-CFA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Canis familiaris 57945 R-CFA-5696091 https://reactome.org/PathwayBrowser/#/R-CFA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Canis familiaris 57945 R-CFA-5696101 https://reactome.org/PathwayBrowser/#/R-CFA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Canis familiaris 57945 R-CFA-5696457 https://reactome.org/PathwayBrowser/#/R-CFA-5696457 BDH2 dehydrogenates 3HBA IEA Canis familiaris 57945 R-CFA-6783939 https://reactome.org/PathwayBrowser/#/R-CFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 57945 R-CFA-6784399 https://reactome.org/PathwayBrowser/#/R-CFA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Canis familiaris 57945 R-CFA-6797955 https://reactome.org/PathwayBrowser/#/R-CFA-6797955 ALDH7A1 oxidises BETALD to BET IEA Canis familiaris 57945 R-CFA-6801328 https://reactome.org/PathwayBrowser/#/R-CFA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Canis familiaris 57945 R-CFA-6806831 https://reactome.org/PathwayBrowser/#/R-CFA-6806831 CYB5Rs reduce MetHb to HbA IEA Canis familiaris 57945 R-CFA-6807826 https://reactome.org/PathwayBrowser/#/R-CFA-6807826 LDHAL6B reduces PYR to LACT IEA Canis familiaris 57945 R-CFA-6808464 https://reactome.org/PathwayBrowser/#/R-CFA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Canis familiaris 57945 R-CFA-6809264 https://reactome.org/PathwayBrowser/#/R-CFA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 57945 R-CFA-6809287 https://reactome.org/PathwayBrowser/#/R-CFA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Canis familiaris 57945 R-CFA-6813749 https://reactome.org/PathwayBrowser/#/R-CFA-6813749 ALDH1A1 oxidises GA to DGA IEA Canis familiaris 57945 R-CFA-70449 https://reactome.org/PathwayBrowser/#/R-CFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Canis familiaris 57945 R-CFA-70482 https://reactome.org/PathwayBrowser/#/R-CFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Canis familiaris 57945 R-CFA-70510 https://reactome.org/PathwayBrowser/#/R-CFA-70510 LDH tetramer oxidises LACT to PYR IEA Canis familiaris 57945 R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Canis familiaris 57945 R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Canis familiaris 57945 R-CFA-70664 https://reactome.org/PathwayBrowser/#/R-CFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 57945 R-CFA-70679 https://reactome.org/PathwayBrowser/#/R-CFA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Canis familiaris 57945 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 57945 R-CFA-70837 https://reactome.org/PathwayBrowser/#/R-CFA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Canis familiaris 57945 R-CFA-70885 https://reactome.org/PathwayBrowser/#/R-CFA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Canis familiaris 57945 R-CFA-70893 https://reactome.org/PathwayBrowser/#/R-CFA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Canis familiaris 57945 R-CFA-70940 https://reactome.org/PathwayBrowser/#/R-CFA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Canis familiaris 57945 R-CFA-70941 https://reactome.org/PathwayBrowser/#/R-CFA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Canis familiaris 57945 R-CFA-70967 https://reactome.org/PathwayBrowser/#/R-CFA-70967 IDH3 complex decarboxylates isocitrate IEA Canis familiaris 57945 R-CFA-70979 https://reactome.org/PathwayBrowser/#/R-CFA-70979 MDH2 dimer dehydrogenates MAL IEA Canis familiaris 57945 R-CFA-71037 https://reactome.org/PathwayBrowser/#/R-CFA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Canis familiaris 57945 R-CFA-71130 https://reactome.org/PathwayBrowser/#/R-CFA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Canis familiaris 57945 R-CFA-71260 https://reactome.org/PathwayBrowser/#/R-CFA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Canis familiaris 57945 R-CFA-71401 https://reactome.org/PathwayBrowser/#/R-CFA-71401 OGDH dimer decarboxylates 2-OG IEA Canis familiaris 57945 R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 57945 R-CFA-71707 https://reactome.org/PathwayBrowser/#/R-CFA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Canis familiaris 57945 R-CFA-71723 https://reactome.org/PathwayBrowser/#/R-CFA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Canis familiaris 57945 R-CFA-71849 https://reactome.org/PathwayBrowser/#/R-CFA-71849 LDH tetramer reduces PYR to LACT IEA Canis familiaris 57945 R-CFA-73794 https://reactome.org/PathwayBrowser/#/R-CFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Canis familiaris 57945 R-CFA-73912 https://reactome.org/PathwayBrowser/#/R-CFA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Canis familiaris 57945 R-CFA-73920 https://reactome.org/PathwayBrowser/#/R-CFA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Canis familiaris 57945 R-CFA-75889 https://reactome.org/PathwayBrowser/#/R-CFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Canis familiaris 57945 R-CFA-77254 https://reactome.org/PathwayBrowser/#/R-CFA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Canis familiaris 57945 R-CFA-77283 https://reactome.org/PathwayBrowser/#/R-CFA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Canis familiaris 57945 R-CFA-77303 https://reactome.org/PathwayBrowser/#/R-CFA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Canis familiaris 57945 R-CFA-77312 https://reactome.org/PathwayBrowser/#/R-CFA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Canis familiaris 57945 R-CFA-77323 https://reactome.org/PathwayBrowser/#/R-CFA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Canis familiaris 57945 R-CFA-77331 https://reactome.org/PathwayBrowser/#/R-CFA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Canis familiaris 57945 R-CFA-77342 https://reactome.org/PathwayBrowser/#/R-CFA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Canis familiaris 57945 R-CFA-888548 https://reactome.org/PathwayBrowser/#/R-CFA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Canis familiaris 57945 R-CFA-8936442 https://reactome.org/PathwayBrowser/#/R-CFA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Canis familiaris 57945 R-CFA-9012268 https://reactome.org/PathwayBrowser/#/R-CFA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Canis familiaris 57945 R-CFA-9023968 https://reactome.org/PathwayBrowser/#/R-CFA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Canis familiaris 57945 R-CFA-9024766 https://reactome.org/PathwayBrowser/#/R-CFA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Canis familiaris 57945 R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 57945 R-CFA-9727349 https://reactome.org/PathwayBrowser/#/R-CFA-9727349 XDH dehydrogenates xanthine to form urate IEA Canis familiaris 57945 R-CFA-9748945 https://reactome.org/PathwayBrowser/#/R-CFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Canis familiaris 57945 R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 57945 R-CFA-9759549 https://reactome.org/PathwayBrowser/#/R-CFA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Canis familiaris 57945 R-CFA-977348 https://reactome.org/PathwayBrowser/#/R-CFA-977348 PHGDH tetramer dehydrogenates 3PG IEA Canis familiaris 57945 R-CFA-9853499 https://reactome.org/PathwayBrowser/#/R-CFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 57945 R-CFA-9856871 https://reactome.org/PathwayBrowser/#/R-CFA-9856871 MDH1 reduces OA IEA Canis familiaris 57945 R-CFA-9861616 https://reactome.org/PathwayBrowser/#/R-CFA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 57945 R-DDI-193455 https://reactome.org/PathwayBrowser/#/R-DDI-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 57945 R-DDI-193508 https://reactome.org/PathwayBrowser/#/R-DDI-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 57945 R-DDI-194642 https://reactome.org/PathwayBrowser/#/R-DDI-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Dictyostelium discoideum 57945 R-DDI-194718 https://reactome.org/PathwayBrowser/#/R-DDI-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Dictyostelium discoideum 57945 R-DDI-198824 https://reactome.org/PathwayBrowser/#/R-DDI-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Dictyostelium discoideum 57945 R-DDI-204617 https://reactome.org/PathwayBrowser/#/R-DDI-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Dictyostelium discoideum 57945 R-DDI-204647 https://reactome.org/PathwayBrowser/#/R-DDI-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Dictyostelium discoideum 57945 R-DDI-204662 https://reactome.org/PathwayBrowser/#/R-DDI-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Dictyostelium discoideum 57945 R-DDI-2162078 https://reactome.org/PathwayBrowser/#/R-DDI-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Dictyostelium discoideum 57945 R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 57945 R-DDI-380608 https://reactome.org/PathwayBrowser/#/R-DDI-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Dictyostelium discoideum 57945 R-DDI-389609 https://reactome.org/PathwayBrowser/#/R-DDI-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Dictyostelium discoideum 57945 R-DDI-389995 https://reactome.org/PathwayBrowser/#/R-DDI-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Dictyostelium discoideum 57945 R-DDI-390251 https://reactome.org/PathwayBrowser/#/R-DDI-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Dictyostelium discoideum 57945 R-DDI-450971 https://reactome.org/PathwayBrowser/#/R-DDI-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Dictyostelium discoideum 57945 R-DDI-508369 https://reactome.org/PathwayBrowser/#/R-DDI-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Dictyostelium discoideum 57945 R-DDI-508473 https://reactome.org/PathwayBrowser/#/R-DDI-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Dictyostelium discoideum 57945 R-DDI-5362522 https://reactome.org/PathwayBrowser/#/R-DDI-5362522 ALDHs oxidise atRAL to atRA IEA Dictyostelium discoideum 57945 R-DDI-5362564 https://reactome.org/PathwayBrowser/#/R-DDI-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Dictyostelium discoideum 57945 R-DDI-5692237 https://reactome.org/PathwayBrowser/#/R-DDI-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Dictyostelium discoideum 57945 R-DDI-5692261 https://reactome.org/PathwayBrowser/#/R-DDI-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Dictyostelium discoideum 57945 R-DDI-5694018 https://reactome.org/PathwayBrowser/#/R-DDI-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Dictyostelium discoideum 57945 R-DDI-5696080 https://reactome.org/PathwayBrowser/#/R-DDI-5696080 ALDH3B1 oxidises HXAL to PALM IEA Dictyostelium discoideum 57945 R-DDI-5696091 https://reactome.org/PathwayBrowser/#/R-DDI-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Dictyostelium discoideum 57945 R-DDI-5696101 https://reactome.org/PathwayBrowser/#/R-DDI-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Dictyostelium discoideum 57945 R-DDI-6783939 https://reactome.org/PathwayBrowser/#/R-DDI-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 57945 R-DDI-6797955 https://reactome.org/PathwayBrowser/#/R-DDI-6797955 ALDH7A1 oxidises BETALD to BET IEA Dictyostelium discoideum 57945 R-DDI-6801328 https://reactome.org/PathwayBrowser/#/R-DDI-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Dictyostelium discoideum 57945 R-DDI-6808464 https://reactome.org/PathwayBrowser/#/R-DDI-6808464 ALDH3B2 oxidises HXAL to PALM IEA Dictyostelium discoideum 57945 R-DDI-6809287 https://reactome.org/PathwayBrowser/#/R-DDI-6809287 NUDT12 hydrolyses NADH to NMNH IEA Dictyostelium discoideum 57945 R-DDI-6813749 https://reactome.org/PathwayBrowser/#/R-DDI-6813749 ALDH1A1 oxidises GA to DGA IEA Dictyostelium discoideum 57945 R-DDI-70449 https://reactome.org/PathwayBrowser/#/R-DDI-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Dictyostelium discoideum 57945 R-DDI-70482 https://reactome.org/PathwayBrowser/#/R-DDI-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Dictyostelium discoideum 57945 R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Dictyostelium discoideum 57945 R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Dictyostelium discoideum 57945 R-DDI-70664 https://reactome.org/PathwayBrowser/#/R-DDI-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 57945 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 57945 R-DDI-70837 https://reactome.org/PathwayBrowser/#/R-DDI-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Dictyostelium discoideum 57945 R-DDI-70885 https://reactome.org/PathwayBrowser/#/R-DDI-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Dictyostelium discoideum 57945 R-DDI-70893 https://reactome.org/PathwayBrowser/#/R-DDI-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 57945 R-DDI-70940 https://reactome.org/PathwayBrowser/#/R-DDI-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Dictyostelium discoideum 57945 R-DDI-70941 https://reactome.org/PathwayBrowser/#/R-DDI-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Dictyostelium discoideum 57945 R-DDI-70967 https://reactome.org/PathwayBrowser/#/R-DDI-70967 IDH3 complex decarboxylates isocitrate IEA Dictyostelium discoideum 57945 R-DDI-71037 https://reactome.org/PathwayBrowser/#/R-DDI-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 57945 R-DDI-71130 https://reactome.org/PathwayBrowser/#/R-DDI-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Dictyostelium discoideum 57945 R-DDI-71401 https://reactome.org/PathwayBrowser/#/R-DDI-71401 OGDH dimer decarboxylates 2-OG IEA Dictyostelium discoideum 57945 R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 57945 R-DDI-71707 https://reactome.org/PathwayBrowser/#/R-DDI-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Dictyostelium discoideum 57945 R-DDI-71723 https://reactome.org/PathwayBrowser/#/R-DDI-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Dictyostelium discoideum 57945 R-DDI-73794 https://reactome.org/PathwayBrowser/#/R-DDI-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Dictyostelium discoideum 57945 R-DDI-8936442 https://reactome.org/PathwayBrowser/#/R-DDI-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Dictyostelium discoideum 57945 R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 57945 R-DDI-9727349 https://reactome.org/PathwayBrowser/#/R-DDI-9727349 XDH dehydrogenates xanthine to form urate IEA Dictyostelium discoideum 57945 R-DDI-9748945 https://reactome.org/PathwayBrowser/#/R-DDI-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Dictyostelium discoideum 57945 R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 57945 R-DDI-9759549 https://reactome.org/PathwayBrowser/#/R-DDI-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Dictyostelium discoideum 57945 R-DDI-9853499 https://reactome.org/PathwayBrowser/#/R-DDI-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 57945 R-DDI-9856871 https://reactome.org/PathwayBrowser/#/R-DDI-9856871 MDH1 reduces OA IEA Dictyostelium discoideum 57945 R-DDI-9861616 https://reactome.org/PathwayBrowser/#/R-DDI-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 57945 R-DME-163217 https://reactome.org/PathwayBrowser/#/R-DME-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Drosophila melanogaster 57945 R-DME-173597 https://reactome.org/PathwayBrowser/#/R-DME-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Drosophila melanogaster 57945 R-DME-193455 https://reactome.org/PathwayBrowser/#/R-DME-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 57945 R-DME-193508 https://reactome.org/PathwayBrowser/#/R-DME-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 57945 R-DME-198824 https://reactome.org/PathwayBrowser/#/R-DME-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Drosophila melanogaster 57945 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 57945 R-DME-204617 https://reactome.org/PathwayBrowser/#/R-DME-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Drosophila melanogaster 57945 R-DME-204647 https://reactome.org/PathwayBrowser/#/R-DME-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Drosophila melanogaster 57945 R-DME-204662 https://reactome.org/PathwayBrowser/#/R-DME-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Drosophila melanogaster 57945 R-DME-2161779 https://reactome.org/PathwayBrowser/#/R-DME-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Drosophila melanogaster 57945 R-DME-2162078 https://reactome.org/PathwayBrowser/#/R-DME-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Drosophila melanogaster 57945 R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 57945 R-DME-380608 https://reactome.org/PathwayBrowser/#/R-DME-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Drosophila melanogaster 57945 R-DME-389609 https://reactome.org/PathwayBrowser/#/R-DME-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Drosophila melanogaster 57945 R-DME-389995 https://reactome.org/PathwayBrowser/#/R-DME-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Drosophila melanogaster 57945 R-DME-390251 https://reactome.org/PathwayBrowser/#/R-DME-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Drosophila melanogaster 57945 R-DME-508369 https://reactome.org/PathwayBrowser/#/R-DME-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Drosophila melanogaster 57945 R-DME-508473 https://reactome.org/PathwayBrowser/#/R-DME-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Drosophila melanogaster 57945 R-DME-5362518 https://reactome.org/PathwayBrowser/#/R-DME-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Drosophila melanogaster 57945 R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster 57945 R-DME-5362564 https://reactome.org/PathwayBrowser/#/R-DME-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Drosophila melanogaster 57945 R-DME-5362721 https://reactome.org/PathwayBrowser/#/R-DME-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 57945 R-DME-5652195 https://reactome.org/PathwayBrowser/#/R-DME-5652195 SORD oxidizes D-sorbitol to Fru IEA Drosophila melanogaster 57945 R-DME-5661290 https://reactome.org/PathwayBrowser/#/R-DME-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Drosophila melanogaster 57945 R-DME-5662471 https://reactome.org/PathwayBrowser/#/R-DME-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Drosophila melanogaster 57945 R-DME-5692237 https://reactome.org/PathwayBrowser/#/R-DME-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Drosophila melanogaster 57945 R-DME-5692261 https://reactome.org/PathwayBrowser/#/R-DME-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Drosophila melanogaster 57945 R-DME-5694018 https://reactome.org/PathwayBrowser/#/R-DME-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Drosophila melanogaster 57945 R-DME-5696080 https://reactome.org/PathwayBrowser/#/R-DME-5696080 ALDH3B1 oxidises HXAL to PALM IEA Drosophila melanogaster 57945 R-DME-5696091 https://reactome.org/PathwayBrowser/#/R-DME-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Drosophila melanogaster 57945 R-DME-6783939 https://reactome.org/PathwayBrowser/#/R-DME-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 57945 R-DME-6797955 https://reactome.org/PathwayBrowser/#/R-DME-6797955 ALDH7A1 oxidises BETALD to BET IEA Drosophila melanogaster 57945 R-DME-6801328 https://reactome.org/PathwayBrowser/#/R-DME-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Drosophila melanogaster 57945 R-DME-6807826 https://reactome.org/PathwayBrowser/#/R-DME-6807826 LDHAL6B reduces PYR to LACT IEA Drosophila melanogaster 57945 R-DME-6808464 https://reactome.org/PathwayBrowser/#/R-DME-6808464 ALDH3B2 oxidises HXAL to PALM IEA Drosophila melanogaster 57945 R-DME-6813749 https://reactome.org/PathwayBrowser/#/R-DME-6813749 ALDH1A1 oxidises GA to DGA IEA Drosophila melanogaster 57945 R-DME-70449 https://reactome.org/PathwayBrowser/#/R-DME-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Drosophila melanogaster 57945 R-DME-70482 https://reactome.org/PathwayBrowser/#/R-DME-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Drosophila melanogaster 57945 R-DME-70510 https://reactome.org/PathwayBrowser/#/R-DME-70510 LDH tetramer oxidises LACT to PYR IEA Drosophila melanogaster 57945 R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Drosophila melanogaster 57945 R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Drosophila melanogaster 57945 R-DME-70664 https://reactome.org/PathwayBrowser/#/R-DME-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 57945 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 57945 R-DME-70837 https://reactome.org/PathwayBrowser/#/R-DME-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Drosophila melanogaster 57945 R-DME-70885 https://reactome.org/PathwayBrowser/#/R-DME-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Drosophila melanogaster 57945 R-DME-70893 https://reactome.org/PathwayBrowser/#/R-DME-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 57945 R-DME-70940 https://reactome.org/PathwayBrowser/#/R-DME-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Drosophila melanogaster 57945 R-DME-70941 https://reactome.org/PathwayBrowser/#/R-DME-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Drosophila melanogaster 57945 R-DME-70967 https://reactome.org/PathwayBrowser/#/R-DME-70967 IDH3 complex decarboxylates isocitrate IEA Drosophila melanogaster 57945 R-DME-70979 https://reactome.org/PathwayBrowser/#/R-DME-70979 MDH2 dimer dehydrogenates MAL IEA Drosophila melanogaster 57945 R-DME-71037 https://reactome.org/PathwayBrowser/#/R-DME-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 57945 R-DME-71130 https://reactome.org/PathwayBrowser/#/R-DME-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Drosophila melanogaster 57945 R-DME-71401 https://reactome.org/PathwayBrowser/#/R-DME-71401 OGDH dimer decarboxylates 2-OG IEA Drosophila melanogaster 57945 R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 57945 R-DME-71707 https://reactome.org/PathwayBrowser/#/R-DME-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Drosophila melanogaster 57945 R-DME-71723 https://reactome.org/PathwayBrowser/#/R-DME-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Drosophila melanogaster 57945 R-DME-71849 https://reactome.org/PathwayBrowser/#/R-DME-71849 LDH tetramer reduces PYR to LACT IEA Drosophila melanogaster 57945 R-DME-73794 https://reactome.org/PathwayBrowser/#/R-DME-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Drosophila melanogaster 57945 R-DME-73912 https://reactome.org/PathwayBrowser/#/R-DME-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Drosophila melanogaster 57945 R-DME-73920 https://reactome.org/PathwayBrowser/#/R-DME-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Drosophila melanogaster 57945 R-DME-75889 https://reactome.org/PathwayBrowser/#/R-DME-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Drosophila melanogaster 57945 R-DME-77283 https://reactome.org/PathwayBrowser/#/R-DME-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Drosophila melanogaster 57945 R-DME-77303 https://reactome.org/PathwayBrowser/#/R-DME-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Drosophila melanogaster 57945 R-DME-888548 https://reactome.org/PathwayBrowser/#/R-DME-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Drosophila melanogaster 57945 R-DME-8936442 https://reactome.org/PathwayBrowser/#/R-DME-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Drosophila melanogaster 57945 R-DME-9012268 https://reactome.org/PathwayBrowser/#/R-DME-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 57945 R-DME-9023968 https://reactome.org/PathwayBrowser/#/R-DME-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Drosophila melanogaster 57945 R-DME-9024766 https://reactome.org/PathwayBrowser/#/R-DME-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Drosophila melanogaster 57945 R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 57945 R-DME-9727349 https://reactome.org/PathwayBrowser/#/R-DME-9727349 XDH dehydrogenates xanthine to form urate IEA Drosophila melanogaster 57945 R-DME-9748945 https://reactome.org/PathwayBrowser/#/R-DME-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Drosophila melanogaster 57945 R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 57945 R-DME-977348 https://reactome.org/PathwayBrowser/#/R-DME-977348 PHGDH tetramer dehydrogenates 3PG IEA Drosophila melanogaster 57945 R-DME-9853499 https://reactome.org/PathwayBrowser/#/R-DME-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 57945 R-DME-9856871 https://reactome.org/PathwayBrowser/#/R-DME-9856871 MDH1 reduces OA IEA Drosophila melanogaster 57945 R-DME-9861616 https://reactome.org/PathwayBrowser/#/R-DME-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 57945 R-DRE-163217 https://reactome.org/PathwayBrowser/#/R-DRE-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Danio rerio 57945 R-DRE-173597 https://reactome.org/PathwayBrowser/#/R-DRE-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Danio rerio 57945 R-DRE-192097 https://reactome.org/PathwayBrowser/#/R-DRE-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Danio rerio 57945 R-DRE-193073 https://reactome.org/PathwayBrowser/#/R-DRE-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Danio rerio 57945 R-DRE-193789 https://reactome.org/PathwayBrowser/#/R-DRE-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Danio rerio 57945 R-DRE-193816 https://reactome.org/PathwayBrowser/#/R-DRE-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Danio rerio 57945 R-DRE-194642 https://reactome.org/PathwayBrowser/#/R-DRE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Danio rerio 57945 R-DRE-194718 https://reactome.org/PathwayBrowser/#/R-DRE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Danio rerio 57945 R-DRE-196350 https://reactome.org/PathwayBrowser/#/R-DRE-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Danio rerio 57945 R-DRE-196372 https://reactome.org/PathwayBrowser/#/R-DRE-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Danio rerio 57945 R-DRE-198824 https://reactome.org/PathwayBrowser/#/R-DRE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Danio rerio 57945 R-DRE-2046084 https://reactome.org/PathwayBrowser/#/R-DRE-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Danio rerio 57945 R-DRE-2046096 https://reactome.org/PathwayBrowser/#/R-DRE-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Danio rerio 57945 R-DRE-2046097 https://reactome.org/PathwayBrowser/#/R-DRE-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 57945 R-DRE-204617 https://reactome.org/PathwayBrowser/#/R-DRE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Danio rerio 57945 R-DRE-204647 https://reactome.org/PathwayBrowser/#/R-DRE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Danio rerio 57945 R-DRE-204662 https://reactome.org/PathwayBrowser/#/R-DRE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Danio rerio 57945 R-DRE-2161779 https://reactome.org/PathwayBrowser/#/R-DRE-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Danio rerio 57945 R-DRE-2162078 https://reactome.org/PathwayBrowser/#/R-DRE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Danio rerio 57945 R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 57945 R-DRE-2454081 https://reactome.org/PathwayBrowser/#/R-DRE-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Danio rerio 57945 R-DRE-380608 https://reactome.org/PathwayBrowser/#/R-DRE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Danio rerio 57945 R-DRE-389609 https://reactome.org/PathwayBrowser/#/R-DRE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Danio rerio 57945 R-DRE-450971 https://reactome.org/PathwayBrowser/#/R-DRE-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Danio rerio 57945 R-DRE-508369 https://reactome.org/PathwayBrowser/#/R-DRE-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Danio rerio 57945 R-DRE-508473 https://reactome.org/PathwayBrowser/#/R-DRE-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Danio rerio 57945 R-DRE-5362518 https://reactome.org/PathwayBrowser/#/R-DRE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Danio rerio 57945 R-DRE-5362522 https://reactome.org/PathwayBrowser/#/R-DRE-5362522 ALDHs oxidise atRAL to atRA IEA Danio rerio 57945 R-DRE-5362564 https://reactome.org/PathwayBrowser/#/R-DRE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Danio rerio 57945 R-DRE-5362721 https://reactome.org/PathwayBrowser/#/R-DRE-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Danio rerio 57945 R-DRE-5661290 https://reactome.org/PathwayBrowser/#/R-DRE-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Danio rerio 57945 R-DRE-5692237 https://reactome.org/PathwayBrowser/#/R-DRE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Danio rerio 57945 R-DRE-5692261 https://reactome.org/PathwayBrowser/#/R-DRE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Danio rerio 57945 R-DRE-5694018 https://reactome.org/PathwayBrowser/#/R-DRE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Danio rerio 57945 R-DRE-5696080 https://reactome.org/PathwayBrowser/#/R-DRE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Danio rerio 57945 R-DRE-5696091 https://reactome.org/PathwayBrowser/#/R-DRE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Danio rerio 57945 R-DRE-5696101 https://reactome.org/PathwayBrowser/#/R-DRE-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Danio rerio 57945 R-DRE-5696457 https://reactome.org/PathwayBrowser/#/R-DRE-5696457 BDH2 dehydrogenates 3HBA IEA Danio rerio 57945 R-DRE-6783939 https://reactome.org/PathwayBrowser/#/R-DRE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 57945 R-DRE-6784399 https://reactome.org/PathwayBrowser/#/R-DRE-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Danio rerio 57945 R-DRE-6797955 https://reactome.org/PathwayBrowser/#/R-DRE-6797955 ALDH7A1 oxidises BETALD to BET IEA Danio rerio 57945 R-DRE-6801328 https://reactome.org/PathwayBrowser/#/R-DRE-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Danio rerio 57945 R-DRE-6806831 https://reactome.org/PathwayBrowser/#/R-DRE-6806831 CYB5Rs reduce MetHb to HbA IEA Danio rerio 57945 R-DRE-6807826 https://reactome.org/PathwayBrowser/#/R-DRE-6807826 LDHAL6B reduces PYR to LACT IEA Danio rerio 57945 R-DRE-6808464 https://reactome.org/PathwayBrowser/#/R-DRE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Danio rerio 57945 R-DRE-6809264 https://reactome.org/PathwayBrowser/#/R-DRE-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Danio rerio 57945 R-DRE-6809287 https://reactome.org/PathwayBrowser/#/R-DRE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Danio rerio 57945 R-DRE-70449 https://reactome.org/PathwayBrowser/#/R-DRE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Danio rerio 57945 R-DRE-70482 https://reactome.org/PathwayBrowser/#/R-DRE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Danio rerio 57945 R-DRE-70510 https://reactome.org/PathwayBrowser/#/R-DRE-70510 LDH tetramer oxidises LACT to PYR IEA Danio rerio 57945 R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Danio rerio 57945 R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Danio rerio 57945 R-DRE-70664 https://reactome.org/PathwayBrowser/#/R-DRE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 57945 R-DRE-70679 https://reactome.org/PathwayBrowser/#/R-DRE-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Danio rerio 57945 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 57945 R-DRE-70837 https://reactome.org/PathwayBrowser/#/R-DRE-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Danio rerio 57945 R-DRE-70885 https://reactome.org/PathwayBrowser/#/R-DRE-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Danio rerio 57945 R-DRE-70893 https://reactome.org/PathwayBrowser/#/R-DRE-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Danio rerio 57945 R-DRE-70940 https://reactome.org/PathwayBrowser/#/R-DRE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Danio rerio 57945 R-DRE-70941 https://reactome.org/PathwayBrowser/#/R-DRE-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Danio rerio 57945 R-DRE-70979 https://reactome.org/PathwayBrowser/#/R-DRE-70979 MDH2 dimer dehydrogenates MAL IEA Danio rerio 57945 R-DRE-71037 https://reactome.org/PathwayBrowser/#/R-DRE-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Danio rerio 57945 R-DRE-71130 https://reactome.org/PathwayBrowser/#/R-DRE-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Danio rerio 57945 R-DRE-71260 https://reactome.org/PathwayBrowser/#/R-DRE-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Danio rerio 57945 R-DRE-71401 https://reactome.org/PathwayBrowser/#/R-DRE-71401 OGDH dimer decarboxylates 2-OG IEA Danio rerio 57945 R-DRE-71707 https://reactome.org/PathwayBrowser/#/R-DRE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Danio rerio 57945 R-DRE-71723 https://reactome.org/PathwayBrowser/#/R-DRE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Danio rerio 57945 R-DRE-71849 https://reactome.org/PathwayBrowser/#/R-DRE-71849 LDH tetramer reduces PYR to LACT IEA Danio rerio 57945 R-DRE-73794 https://reactome.org/PathwayBrowser/#/R-DRE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Danio rerio 57945 R-DRE-73912 https://reactome.org/PathwayBrowser/#/R-DRE-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Danio rerio 57945 R-DRE-73920 https://reactome.org/PathwayBrowser/#/R-DRE-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Danio rerio 57945 R-DRE-75889 https://reactome.org/PathwayBrowser/#/R-DRE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Danio rerio 57945 R-DRE-77254 https://reactome.org/PathwayBrowser/#/R-DRE-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Danio rerio 57945 R-DRE-77283 https://reactome.org/PathwayBrowser/#/R-DRE-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Danio rerio 57945 R-DRE-77303 https://reactome.org/PathwayBrowser/#/R-DRE-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Danio rerio 57945 R-DRE-77312 https://reactome.org/PathwayBrowser/#/R-DRE-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Danio rerio 57945 R-DRE-77323 https://reactome.org/PathwayBrowser/#/R-DRE-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Danio rerio 57945 R-DRE-77331 https://reactome.org/PathwayBrowser/#/R-DRE-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Danio rerio 57945 R-DRE-77342 https://reactome.org/PathwayBrowser/#/R-DRE-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Danio rerio 57945 R-DRE-8936442 https://reactome.org/PathwayBrowser/#/R-DRE-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Danio rerio 57945 R-DRE-9012268 https://reactome.org/PathwayBrowser/#/R-DRE-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Danio rerio 57945 R-DRE-9023968 https://reactome.org/PathwayBrowser/#/R-DRE-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Danio rerio 57945 R-DRE-9024766 https://reactome.org/PathwayBrowser/#/R-DRE-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Danio rerio 57945 R-DRE-9748945 https://reactome.org/PathwayBrowser/#/R-DRE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Danio rerio 57945 R-DRE-9759549 https://reactome.org/PathwayBrowser/#/R-DRE-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Danio rerio 57945 R-DRE-9853499 https://reactome.org/PathwayBrowser/#/R-DRE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Danio rerio 57945 R-DRE-9856871 https://reactome.org/PathwayBrowser/#/R-DRE-9856871 MDH1 reduces OA IEA Danio rerio 57945 R-FCA-164926 https://reactome.org/PathwayBrowser/#/R-FCA-164926 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ TAS Felis catus 57945 R-GGA-109343 https://reactome.org/PathwayBrowser/#/R-GGA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Gallus gallus 57945 R-GGA-1614362 https://reactome.org/PathwayBrowser/#/R-GGA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Gallus gallus 57945 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Gallus gallus 57945 R-GGA-173597 https://reactome.org/PathwayBrowser/#/R-GGA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Gallus gallus 57945 R-GGA-193073 https://reactome.org/PathwayBrowser/#/R-GGA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Gallus gallus 57945 R-GGA-193455 https://reactome.org/PathwayBrowser/#/R-GGA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 57945 R-GGA-193508 https://reactome.org/PathwayBrowser/#/R-GGA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 57945 R-GGA-194642 https://reactome.org/PathwayBrowser/#/R-GGA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Gallus gallus 57945 R-GGA-194718 https://reactome.org/PathwayBrowser/#/R-GGA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Gallus gallus 57945 R-GGA-196350 https://reactome.org/PathwayBrowser/#/R-GGA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Gallus gallus 57945 R-GGA-196372 https://reactome.org/PathwayBrowser/#/R-GGA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Gallus gallus 57945 R-GGA-198824 https://reactome.org/PathwayBrowser/#/R-GGA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Gallus gallus 57945 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 57945 R-GGA-2046084 https://reactome.org/PathwayBrowser/#/R-GGA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Gallus gallus 57945 R-GGA-2046089 https://reactome.org/PathwayBrowser/#/R-GGA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Gallus gallus 57945 R-GGA-2046092 https://reactome.org/PathwayBrowser/#/R-GGA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Gallus gallus 57945 R-GGA-2046096 https://reactome.org/PathwayBrowser/#/R-GGA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Gallus gallus 57945 R-GGA-2046097 https://reactome.org/PathwayBrowser/#/R-GGA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 57945 R-GGA-204662 https://reactome.org/PathwayBrowser/#/R-GGA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Gallus gallus 57945 R-GGA-2161779 https://reactome.org/PathwayBrowser/#/R-GGA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Gallus gallus 57945 R-GGA-2162078 https://reactome.org/PathwayBrowser/#/R-GGA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Gallus gallus 57945 R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 57945 R-GGA-2454081 https://reactome.org/PathwayBrowser/#/R-GGA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Gallus gallus 57945 R-GGA-352921 https://reactome.org/PathwayBrowser/#/R-GGA-352921 1,3-bisphosphoglycerate + NADH + H+ <=> glyceraldehyde 3-phosphate + NAD+ + phosphate TAS Gallus gallus 57945 R-GGA-352956 https://reactome.org/PathwayBrowser/#/R-GGA-352956 glyceraldehyde 3-phosphate + NAD+ + phosphate <=> 1,3-bisphosphoglycerate + NADH + H+ TAS Gallus gallus 57945 R-GGA-372422 https://reactome.org/PathwayBrowser/#/R-GGA-372422 oxaloacetate + NADH + H+ <=> malate + NAD+ TAS Gallus gallus 57945 R-GGA-372855 https://reactome.org/PathwayBrowser/#/R-GGA-372855 malate + NAD+ <=> oxaloacetate + NADH + H+ TAS Gallus gallus 57945 R-GGA-372903 https://reactome.org/PathwayBrowser/#/R-GGA-372903 lactate + NAD+ <=> pyruvate + NADH + H+ TAS Gallus gallus 57945 R-GGA-372910 https://reactome.org/PathwayBrowser/#/R-GGA-372910 pyruvate + NADH + H+ <=> lactate + NAD+ TAS Gallus gallus 57945 R-GGA-373024 https://reactome.org/PathwayBrowser/#/R-GGA-373024 isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ IEA Gallus gallus 57945 R-GGA-373042 https://reactome.org/PathwayBrowser/#/R-GGA-373042 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ IEA Gallus gallus 57945 R-GGA-373047 https://reactome.org/PathwayBrowser/#/R-GGA-373047 malate + NAD+ <=> oxaloacetate + NADH + H+ IEA Gallus gallus 57945 R-GGA-373177 https://reactome.org/PathwayBrowser/#/R-GGA-373177 pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ TAS Gallus gallus 57945 R-GGA-380608 https://reactome.org/PathwayBrowser/#/R-GGA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Gallus gallus 57945 R-GGA-389609 https://reactome.org/PathwayBrowser/#/R-GGA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Gallus gallus 57945 R-GGA-389995 https://reactome.org/PathwayBrowser/#/R-GGA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Gallus gallus 57945 R-GGA-390251 https://reactome.org/PathwayBrowser/#/R-GGA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 57945 R-GGA-421158 https://reactome.org/PathwayBrowser/#/R-GGA-421158 xanthine + H2O + NAD+ => urate + NADH + H+ TAS Gallus gallus 57945 R-GGA-421161 https://reactome.org/PathwayBrowser/#/R-GGA-421161 hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ TAS Gallus gallus 57945 R-GGA-421222 https://reactome.org/PathwayBrowser/#/R-GGA-421222 inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ IEA Gallus gallus 57945 R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 57945 R-GGA-450971 https://reactome.org/PathwayBrowser/#/R-GGA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Gallus gallus 57945 R-GGA-508369 https://reactome.org/PathwayBrowser/#/R-GGA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Gallus gallus 57945 R-GGA-508473 https://reactome.org/PathwayBrowser/#/R-GGA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Gallus gallus 57945 R-GGA-5362518 https://reactome.org/PathwayBrowser/#/R-GGA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Gallus gallus 57945 R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus 57945 R-GGA-5362564 https://reactome.org/PathwayBrowser/#/R-GGA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Gallus gallus 57945 R-GGA-5362721 https://reactome.org/PathwayBrowser/#/R-GGA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Gallus gallus 57945 R-GGA-5652195 https://reactome.org/PathwayBrowser/#/R-GGA-5652195 SORD oxidizes D-sorbitol to Fru IEA Gallus gallus 57945 R-GGA-5661290 https://reactome.org/PathwayBrowser/#/R-GGA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Gallus gallus 57945 R-GGA-5662471 https://reactome.org/PathwayBrowser/#/R-GGA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Gallus gallus 57945 R-GGA-5692237 https://reactome.org/PathwayBrowser/#/R-GGA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Gallus gallus 57945 R-GGA-5692261 https://reactome.org/PathwayBrowser/#/R-GGA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Gallus gallus 57945 R-GGA-5694018 https://reactome.org/PathwayBrowser/#/R-GGA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Gallus gallus 57945 R-GGA-5696080 https://reactome.org/PathwayBrowser/#/R-GGA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Gallus gallus 57945 R-GGA-5696101 https://reactome.org/PathwayBrowser/#/R-GGA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Gallus gallus 57945 R-GGA-5696457 https://reactome.org/PathwayBrowser/#/R-GGA-5696457 BDH2 dehydrogenates 3HBA IEA Gallus gallus 57945 R-GGA-6783939 https://reactome.org/PathwayBrowser/#/R-GGA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 57945 R-GGA-6784399 https://reactome.org/PathwayBrowser/#/R-GGA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Gallus gallus 57945 R-GGA-6797955 https://reactome.org/PathwayBrowser/#/R-GGA-6797955 ALDH7A1 oxidises BETALD to BET IEA Gallus gallus 57945 R-GGA-6801328 https://reactome.org/PathwayBrowser/#/R-GGA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Gallus gallus 57945 R-GGA-6806831 https://reactome.org/PathwayBrowser/#/R-GGA-6806831 CYB5Rs reduce MetHb to HbA IEA Gallus gallus 57945 R-GGA-6807826 https://reactome.org/PathwayBrowser/#/R-GGA-6807826 LDHAL6B reduces PYR to LACT IEA Gallus gallus 57945 R-GGA-6808464 https://reactome.org/PathwayBrowser/#/R-GGA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Gallus gallus 57945 R-GGA-6809264 https://reactome.org/PathwayBrowser/#/R-GGA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 57945 R-GGA-6809287 https://reactome.org/PathwayBrowser/#/R-GGA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Gallus gallus 57945 R-GGA-6813749 https://reactome.org/PathwayBrowser/#/R-GGA-6813749 ALDH1A1 oxidises GA to DGA IEA Gallus gallus 57945 R-GGA-70449 https://reactome.org/PathwayBrowser/#/R-GGA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Gallus gallus 57945 R-GGA-70482 https://reactome.org/PathwayBrowser/#/R-GGA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Gallus gallus 57945 R-GGA-70510 https://reactome.org/PathwayBrowser/#/R-GGA-70510 LDH tetramer oxidises LACT to PYR IEA Gallus gallus 57945 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Gallus gallus 57945 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Gallus gallus 57945 R-GGA-70664 https://reactome.org/PathwayBrowser/#/R-GGA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 57945 R-GGA-70679 https://reactome.org/PathwayBrowser/#/R-GGA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Gallus gallus 57945 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 57945 R-GGA-70837 https://reactome.org/PathwayBrowser/#/R-GGA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Gallus gallus 57945 R-GGA-70885 https://reactome.org/PathwayBrowser/#/R-GGA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Gallus gallus 57945 R-GGA-70893 https://reactome.org/PathwayBrowser/#/R-GGA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Gallus gallus 57945 R-GGA-70940 https://reactome.org/PathwayBrowser/#/R-GGA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Gallus gallus 57945 R-GGA-70941 https://reactome.org/PathwayBrowser/#/R-GGA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Gallus gallus 57945 R-GGA-70979 https://reactome.org/PathwayBrowser/#/R-GGA-70979 MDH2 dimer dehydrogenates MAL IEA Gallus gallus 57945 R-GGA-71037 https://reactome.org/PathwayBrowser/#/R-GGA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Gallus gallus 57945 R-GGA-71130 https://reactome.org/PathwayBrowser/#/R-GGA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Gallus gallus 57945 R-GGA-71260 https://reactome.org/PathwayBrowser/#/R-GGA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Gallus gallus 57945 R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus 57945 R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 57945 R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus 57945 R-GGA-71723 https://reactome.org/PathwayBrowser/#/R-GGA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Gallus gallus 57945 R-GGA-71849 https://reactome.org/PathwayBrowser/#/R-GGA-71849 LDH tetramer reduces PYR to LACT IEA Gallus gallus 57945 R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus 57945 R-GGA-73912 https://reactome.org/PathwayBrowser/#/R-GGA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Gallus gallus 57945 R-GGA-73920 https://reactome.org/PathwayBrowser/#/R-GGA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Gallus gallus 57945 R-GGA-75889 https://reactome.org/PathwayBrowser/#/R-GGA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Gallus gallus 57945 R-GGA-77254 https://reactome.org/PathwayBrowser/#/R-GGA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Gallus gallus 57945 R-GGA-77283 https://reactome.org/PathwayBrowser/#/R-GGA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Gallus gallus 57945 R-GGA-77303 https://reactome.org/PathwayBrowser/#/R-GGA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Gallus gallus 57945 R-GGA-77312 https://reactome.org/PathwayBrowser/#/R-GGA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Gallus gallus 57945 R-GGA-77323 https://reactome.org/PathwayBrowser/#/R-GGA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Gallus gallus 57945 R-GGA-77331 https://reactome.org/PathwayBrowser/#/R-GGA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Gallus gallus 57945 R-GGA-77342 https://reactome.org/PathwayBrowser/#/R-GGA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Gallus gallus 57945 R-GGA-888548 https://reactome.org/PathwayBrowser/#/R-GGA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Gallus gallus 57945 R-GGA-8936442 https://reactome.org/PathwayBrowser/#/R-GGA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Gallus gallus 57945 R-GGA-9023968 https://reactome.org/PathwayBrowser/#/R-GGA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Gallus gallus 57945 R-GGA-9024766 https://reactome.org/PathwayBrowser/#/R-GGA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Gallus gallus 57945 R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 57945 R-GGA-9727349 https://reactome.org/PathwayBrowser/#/R-GGA-9727349 XDH dehydrogenates xanthine to form urate IEA Gallus gallus 57945 R-GGA-9748945 https://reactome.org/PathwayBrowser/#/R-GGA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Gallus gallus 57945 R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 57945 R-GGA-9759549 https://reactome.org/PathwayBrowser/#/R-GGA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Gallus gallus 57945 R-GGA-9853499 https://reactome.org/PathwayBrowser/#/R-GGA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 57945 R-GGA-9856871 https://reactome.org/PathwayBrowser/#/R-GGA-9856871 MDH1 reduces OA IEA Gallus gallus 57945 R-GGA-9861616 https://reactome.org/PathwayBrowser/#/R-GGA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 57945 R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 57945 R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 57945 R-HSA-109343 https://reactome.org/PathwayBrowser/#/R-HSA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA TAS Homo sapiens 57945 R-HSA-1222412 https://reactome.org/PathwayBrowser/#/R-HSA-1222412 lpdC dimer reactivates dlaT TAS Homo sapiens 57945 R-HSA-1222583 https://reactome.org/PathwayBrowser/#/R-HSA-1222583 MscR reduces nitrosomycothiol to ammonia TAS Homo sapiens 57945 R-HSA-1614362 https://reactome.org/PathwayBrowser/#/R-HSA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases TAS Homo sapiens 57945 R-HSA-163217 https://reactome.org/PathwayBrowser/#/R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 TAS Homo sapiens 57945 R-HSA-173597 https://reactome.org/PathwayBrowser/#/R-HSA-173597 UDP-glucose is oxidised to UDP-glucuronate TAS Homo sapiens 57945 R-HSA-192097 https://reactome.org/PathwayBrowser/#/R-HSA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one TAS Homo sapiens 57945 R-HSA-193073 https://reactome.org/PathwayBrowser/#/R-HSA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST TAS Homo sapiens 57945 R-HSA-193455 https://reactome.org/PathwayBrowser/#/R-HSA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 57945 R-HSA-193508 https://reactome.org/PathwayBrowser/#/R-HSA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 57945 R-HSA-193789 https://reactome.org/PathwayBrowser/#/R-HSA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one TAS Homo sapiens 57945 R-HSA-193816 https://reactome.org/PathwayBrowser/#/R-HSA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one TAS Homo sapiens 57945 R-HSA-194642 https://reactome.org/PathwayBrowser/#/R-HSA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one TAS Homo sapiens 57945 R-HSA-194718 https://reactome.org/PathwayBrowser/#/R-HSA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) TAS Homo sapiens 57945 R-HSA-196350 https://reactome.org/PathwayBrowser/#/R-HSA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione TAS Homo sapiens 57945 R-HSA-196372 https://reactome.org/PathwayBrowser/#/R-HSA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol TAS Homo sapiens 57945 R-HSA-198824 https://reactome.org/PathwayBrowser/#/R-HSA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme TAS Homo sapiens 57945 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 57945 R-HSA-2046084 https://reactome.org/PathwayBrowser/#/R-HSA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA TAS Homo sapiens 57945 R-HSA-2046089 https://reactome.org/PathwayBrowser/#/R-HSA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA TAS Homo sapiens 57945 R-HSA-2046092 https://reactome.org/PathwayBrowser/#/R-HSA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA TAS Homo sapiens 57945 R-HSA-2046096 https://reactome.org/PathwayBrowser/#/R-HSA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA TAS Homo sapiens 57945 R-HSA-2046097 https://reactome.org/PathwayBrowser/#/R-HSA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 57945 R-HSA-2046099 https://reactome.org/PathwayBrowser/#/R-HSA-2046099 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA IEA Homo sapiens 57945 R-HSA-204617 https://reactome.org/PathwayBrowser/#/R-HSA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A TAS Homo sapiens 57945 R-HSA-204647 https://reactome.org/PathwayBrowser/#/R-HSA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine TAS Homo sapiens 57945 R-HSA-204662 https://reactome.org/PathwayBrowser/#/R-HSA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A TAS Homo sapiens 57945 R-HSA-2161662 https://reactome.org/PathwayBrowser/#/R-HSA-2161662 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD IEA Homo sapiens 57945 R-HSA-2161732 https://reactome.org/PathwayBrowser/#/R-HSA-2161732 TXB2 is converted to 11dh-TXB2 by TXDH TAS Homo sapiens 57945 R-HSA-2161779 https://reactome.org/PathwayBrowser/#/R-HSA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD TAS Homo sapiens 57945 R-HSA-2161789 https://reactome.org/PathwayBrowser/#/R-HSA-2161789 15S-HETE is oxidised to 15-oxoETE by 15-HEDH TAS Homo sapiens 57945 R-HSA-2162078 https://reactome.org/PathwayBrowser/#/R-HSA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ TAS Homo sapiens 57945 R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 57945 R-HSA-2454081 https://reactome.org/PathwayBrowser/#/R-HSA-2454081 RDH5 oxidises 11cROL to 11cRAL TAS Homo sapiens 57945 R-HSA-380608 https://reactome.org/PathwayBrowser/#/R-HSA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid TAS Homo sapiens 57945 R-HSA-389609 https://reactome.org/PathwayBrowser/#/R-HSA-389609 ALDH3A2-2 oxidizes pristanal to pristanate TAS Homo sapiens 57945 R-HSA-389995 https://reactome.org/PathwayBrowser/#/R-HSA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ TAS Homo sapiens 57945 R-HSA-390251 https://reactome.org/PathwayBrowser/#/R-HSA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 57945 R-HSA-390276 https://reactome.org/PathwayBrowser/#/R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA TAS Homo sapiens 57945 R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA TAS Homo sapiens 57945 R-HSA-450971 https://reactome.org/PathwayBrowser/#/R-HSA-450971 NNT dimer transfers proton from NADPH to NAD+ TAS Homo sapiens 57945 R-HSA-508369 https://reactome.org/PathwayBrowser/#/R-HSA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ TAS Homo sapiens 57945 R-HSA-508473 https://reactome.org/PathwayBrowser/#/R-HSA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ TAS Homo sapiens 57945 R-HSA-5362518 https://reactome.org/PathwayBrowser/#/R-HSA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL TAS Homo sapiens 57945 R-HSA-5362522 https://reactome.org/PathwayBrowser/#/R-HSA-5362522 ALDHs oxidise atRAL to atRA TAS Homo sapiens 57945 R-HSA-5362564 https://reactome.org/PathwayBrowser/#/R-HSA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro TAS Homo sapiens 57945 R-HSA-5362721 https://reactome.org/PathwayBrowser/#/R-HSA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL TAS Homo sapiens 57945 R-HSA-5652195 https://reactome.org/PathwayBrowser/#/R-HSA-5652195 SORD oxidizes D-sorbitol to Fru TAS Homo sapiens 57945 R-HSA-5661290 https://reactome.org/PathwayBrowser/#/R-HSA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate TAS Homo sapiens 57945 R-HSA-5662471 https://reactome.org/PathwayBrowser/#/R-HSA-5662471 SORD tetramer oxidizes xylitol to D-xylulose TAS Homo sapiens 57945 R-HSA-5692237 https://reactome.org/PathwayBrowser/#/R-HSA-5692237 ADH5 oxidises S-HMGSH to S-FGSH TAS Homo sapiens 57945 R-HSA-5692261 https://reactome.org/PathwayBrowser/#/R-HSA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM TAS Homo sapiens 57945 R-HSA-5694018 https://reactome.org/PathwayBrowser/#/R-HSA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate TAS Homo sapiens 57945 R-HSA-5696080 https://reactome.org/PathwayBrowser/#/R-HSA-5696080 ALDH3B1 oxidises HXAL to PALM TAS Homo sapiens 57945 R-HSA-5696091 https://reactome.org/PathwayBrowser/#/R-HSA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH TAS Homo sapiens 57945 R-HSA-5696101 https://reactome.org/PathwayBrowser/#/R-HSA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA TAS Homo sapiens 57945 R-HSA-5696457 https://reactome.org/PathwayBrowser/#/R-HSA-5696457 BDH2 dehydrogenates 3HBA TAS Homo sapiens 57945 R-HSA-6782296 https://reactome.org/PathwayBrowser/#/R-HSA-6782296 DUS2:EPRS reduces uridine to dihydrouridine in tRNAs IEA Homo sapiens 57945 R-HSA-6783939 https://reactome.org/PathwayBrowser/#/R-HSA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 57945 R-HSA-6784399 https://reactome.org/PathwayBrowser/#/R-HSA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate TAS Homo sapiens 57945 R-HSA-6797955 https://reactome.org/PathwayBrowser/#/R-HSA-6797955 ALDH7A1 oxidises BETALD to BET TAS Homo sapiens 57945 R-HSA-6798667 https://reactome.org/PathwayBrowser/#/R-HSA-6798667 TDH tetramer oxidises L-Thr to 2A-3OB TAS Homo sapiens 57945 R-HSA-6801328 https://reactome.org/PathwayBrowser/#/R-HSA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF TAS Homo sapiens 57945 R-HSA-6806831 https://reactome.org/PathwayBrowser/#/R-HSA-6806831 CYB5Rs reduce MetHb to HbA TAS Homo sapiens 57945 R-HSA-6807826 https://reactome.org/PathwayBrowser/#/R-HSA-6807826 LDHAL6B reduces PYR to LACT TAS Homo sapiens 57945 R-HSA-6808464 https://reactome.org/PathwayBrowser/#/R-HSA-6808464 ALDH3B2 oxidises HXAL to PALM TAS Homo sapiens 57945 R-HSA-6809264 https://reactome.org/PathwayBrowser/#/R-HSA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 57945 R-HSA-6809287 https://reactome.org/PathwayBrowser/#/R-HSA-6809287 NUDT12 hydrolyses NADH to NMNH TAS Homo sapiens 57945 R-HSA-6813749 https://reactome.org/PathwayBrowser/#/R-HSA-6813749 ALDH1A1 oxidises GA to DGA TAS Homo sapiens 57945 R-HSA-70449 https://reactome.org/PathwayBrowser/#/R-HSA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ TAS Homo sapiens 57945 R-HSA-70482 https://reactome.org/PathwayBrowser/#/R-HSA-70482 GAPDH tetramers reduce 1,3BPG to GA3P TAS Homo sapiens 57945 R-HSA-70510 https://reactome.org/PathwayBrowser/#/R-HSA-70510 LDH tetramer oxidises LACT to PYR TAS Homo sapiens 57945 R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] TAS Homo sapiens 57945 R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] TAS Homo sapiens 57945 R-HSA-70664 https://reactome.org/PathwayBrowser/#/R-HSA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 57945 R-HSA-70679 https://reactome.org/PathwayBrowser/#/R-HSA-70679 ALDH4A1 oxidises L-GluSS to Glu TAS Homo sapiens 57945 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 57945 R-HSA-70837 https://reactome.org/PathwayBrowser/#/R-HSA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ TAS Homo sapiens 57945 R-HSA-70885 https://reactome.org/PathwayBrowser/#/R-HSA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ TAS Homo sapiens 57945 R-HSA-70893 https://reactome.org/PathwayBrowser/#/R-HSA-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ TAS Homo sapiens 57945 R-HSA-70940 https://reactome.org/PathwayBrowser/#/R-HSA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ TAS Homo sapiens 57945 R-HSA-70941 https://reactome.org/PathwayBrowser/#/R-HSA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ TAS Homo sapiens 57945 R-HSA-70967 https://reactome.org/PathwayBrowser/#/R-HSA-70967 IDH3 complex decarboxylates isocitrate TAS Homo sapiens 57945 R-HSA-70979 https://reactome.org/PathwayBrowser/#/R-HSA-70979 MDH2 dimer dehydrogenates MAL TAS Homo sapiens 57945 R-HSA-71037 https://reactome.org/PathwayBrowser/#/R-HSA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ TAS Homo sapiens 57945 R-HSA-71130 https://reactome.org/PathwayBrowser/#/R-HSA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ TAS Homo sapiens 57945 R-HSA-71239 https://reactome.org/PathwayBrowser/#/R-HSA-71239 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ IEA Homo sapiens 57945 R-HSA-71260 https://reactome.org/PathwayBrowser/#/R-HSA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT TAS Homo sapiens 57945 R-HSA-71401 https://reactome.org/PathwayBrowser/#/R-HSA-71401 OGDH dimer decarboxylates 2-OG TAS Homo sapiens 57945 R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 57945 R-HSA-71707 https://reactome.org/PathwayBrowser/#/R-HSA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ TAS Homo sapiens 57945 R-HSA-71723 https://reactome.org/PathwayBrowser/#/R-HSA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] TAS Homo sapiens 57945 R-HSA-71849 https://reactome.org/PathwayBrowser/#/R-HSA-71849 LDH tetramer reduces PYR to LACT TAS Homo sapiens 57945 R-HSA-73794 https://reactome.org/PathwayBrowser/#/R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] TAS Homo sapiens 57945 R-HSA-73912 https://reactome.org/PathwayBrowser/#/R-HSA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ TAS Homo sapiens 57945 R-HSA-73920 https://reactome.org/PathwayBrowser/#/R-HSA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ TAS Homo sapiens 57945 R-HSA-75889 https://reactome.org/PathwayBrowser/#/R-HSA-75889 DHAP is converted to G3P by GPD1/GPD1L TAS Homo sapiens 57945 R-HSA-77254 https://reactome.org/PathwayBrowser/#/R-HSA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H TAS Homo sapiens 57945 R-HSA-77283 https://reactome.org/PathwayBrowser/#/R-HSA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H TAS Homo sapiens 57945 R-HSA-77303 https://reactome.org/PathwayBrowser/#/R-HSA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H TAS Homo sapiens 57945 R-HSA-77312 https://reactome.org/PathwayBrowser/#/R-HSA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H TAS Homo sapiens 57945 R-HSA-77323 https://reactome.org/PathwayBrowser/#/R-HSA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H TAS Homo sapiens 57945 R-HSA-77331 https://reactome.org/PathwayBrowser/#/R-HSA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H TAS Homo sapiens 57945 R-HSA-77342 https://reactome.org/PathwayBrowser/#/R-HSA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H TAS Homo sapiens 57945 R-HSA-888548 https://reactome.org/PathwayBrowser/#/R-HSA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA TAS Homo sapiens 57945 R-HSA-8936442 https://reactome.org/PathwayBrowser/#/R-HSA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds TAS Homo sapiens 57945 R-HSA-8956427 https://reactome.org/PathwayBrowser/#/R-HSA-8956427 RETSAT reduces atROL to at-13,14-dhROL IEA Homo sapiens 57945 R-HSA-9012268 https://reactome.org/PathwayBrowser/#/R-HSA-9012268 ME2 tetramer decarboxylates MAL to PYR TAS Homo sapiens 57945 R-HSA-9023968 https://reactome.org/PathwayBrowser/#/R-HSA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 TAS Homo sapiens 57945 R-HSA-9024766 https://reactome.org/PathwayBrowser/#/R-HSA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 TAS Homo sapiens 57945 R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 57945 R-HSA-9727349 https://reactome.org/PathwayBrowser/#/R-HSA-9727349 XDH dehydrogenates xanthine to form urate TAS Homo sapiens 57945 R-HSA-9748945 https://reactome.org/PathwayBrowser/#/R-HSA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP TAS Homo sapiens 57945 R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 57945 R-HSA-9759549 https://reactome.org/PathwayBrowser/#/R-HSA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin TAS Homo sapiens 57945 R-HSA-977348 https://reactome.org/PathwayBrowser/#/R-HSA-977348 PHGDH tetramer dehydrogenates 3PG TAS Homo sapiens 57945 R-HSA-9853499 https://reactome.org/PathwayBrowser/#/R-HSA-9853499 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 57945 R-HSA-9856871 https://reactome.org/PathwayBrowser/#/R-HSA-9856871 MDH1 reduces OA TAS Homo sapiens 57945 R-HSA-9861616 https://reactome.org/PathwayBrowser/#/R-HSA-9861616 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 57945 R-MMU-109343 https://reactome.org/PathwayBrowser/#/R-MMU-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Mus musculus 57945 R-MMU-1614362 https://reactome.org/PathwayBrowser/#/R-MMU-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Mus musculus 57945 R-MMU-163217 https://reactome.org/PathwayBrowser/#/R-MMU-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Mus musculus 57945 R-MMU-173597 https://reactome.org/PathwayBrowser/#/R-MMU-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Mus musculus 57945 R-MMU-192097 https://reactome.org/PathwayBrowser/#/R-MMU-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Mus musculus 57945 R-MMU-193073 https://reactome.org/PathwayBrowser/#/R-MMU-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Mus musculus 57945 R-MMU-193455 https://reactome.org/PathwayBrowser/#/R-MMU-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 57945 R-MMU-193508 https://reactome.org/PathwayBrowser/#/R-MMU-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 57945 R-MMU-193789 https://reactome.org/PathwayBrowser/#/R-MMU-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Mus musculus 57945 R-MMU-193816 https://reactome.org/PathwayBrowser/#/R-MMU-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Mus musculus 57945 R-MMU-194642 https://reactome.org/PathwayBrowser/#/R-MMU-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Mus musculus 57945 R-MMU-194718 https://reactome.org/PathwayBrowser/#/R-MMU-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Mus musculus 57945 R-MMU-196350 https://reactome.org/PathwayBrowser/#/R-MMU-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Mus musculus 57945 R-MMU-196372 https://reactome.org/PathwayBrowser/#/R-MMU-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Mus musculus 57945 R-MMU-198824 https://reactome.org/PathwayBrowser/#/R-MMU-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Mus musculus 57945 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 57945 R-MMU-2046084 https://reactome.org/PathwayBrowser/#/R-MMU-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Mus musculus 57945 R-MMU-2046089 https://reactome.org/PathwayBrowser/#/R-MMU-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Mus musculus 57945 R-MMU-2046092 https://reactome.org/PathwayBrowser/#/R-MMU-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Mus musculus 57945 R-MMU-2046096 https://reactome.org/PathwayBrowser/#/R-MMU-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Mus musculus 57945 R-MMU-2046097 https://reactome.org/PathwayBrowser/#/R-MMU-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 57945 R-MMU-204617 https://reactome.org/PathwayBrowser/#/R-MMU-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Mus musculus 57945 R-MMU-204647 https://reactome.org/PathwayBrowser/#/R-MMU-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Mus musculus 57945 R-MMU-204662 https://reactome.org/PathwayBrowser/#/R-MMU-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Mus musculus 57945 R-MMU-2161779 https://reactome.org/PathwayBrowser/#/R-MMU-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Mus musculus 57945 R-MMU-2162078 https://reactome.org/PathwayBrowser/#/R-MMU-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Mus musculus 57945 R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 57945 R-MMU-2454081 https://reactome.org/PathwayBrowser/#/R-MMU-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Mus musculus 57945 R-MMU-380608 https://reactome.org/PathwayBrowser/#/R-MMU-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Mus musculus 57945 R-MMU-389609 https://reactome.org/PathwayBrowser/#/R-MMU-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Mus musculus 57945 R-MMU-389995 https://reactome.org/PathwayBrowser/#/R-MMU-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Mus musculus 57945 R-MMU-390251 https://reactome.org/PathwayBrowser/#/R-MMU-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 57945 R-MMU-450971 https://reactome.org/PathwayBrowser/#/R-MMU-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Mus musculus 57945 R-MMU-508369 https://reactome.org/PathwayBrowser/#/R-MMU-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Mus musculus 57945 R-MMU-508473 https://reactome.org/PathwayBrowser/#/R-MMU-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Mus musculus 57945 R-MMU-5362518 https://reactome.org/PathwayBrowser/#/R-MMU-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Mus musculus 57945 R-MMU-5362522 https://reactome.org/PathwayBrowser/#/R-MMU-5362522 ALDHs oxidise atRAL to atRA IEA Mus musculus 57945 R-MMU-5362564 https://reactome.org/PathwayBrowser/#/R-MMU-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Mus musculus 57945 R-MMU-5362721 https://reactome.org/PathwayBrowser/#/R-MMU-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Mus musculus 57945 R-MMU-5652195 https://reactome.org/PathwayBrowser/#/R-MMU-5652195 SORD oxidizes D-sorbitol to Fru IEA Mus musculus 57945 R-MMU-5661290 https://reactome.org/PathwayBrowser/#/R-MMU-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Mus musculus 57945 R-MMU-5662471 https://reactome.org/PathwayBrowser/#/R-MMU-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Mus musculus 57945 R-MMU-5692237 https://reactome.org/PathwayBrowser/#/R-MMU-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Mus musculus 57945 R-MMU-5692261 https://reactome.org/PathwayBrowser/#/R-MMU-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Mus musculus 57945 R-MMU-5694018 https://reactome.org/PathwayBrowser/#/R-MMU-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Mus musculus 57945 R-MMU-5696080 https://reactome.org/PathwayBrowser/#/R-MMU-5696080 ALDH3B1 oxidises HXAL to PALM IEA Mus musculus 57945 R-MMU-5696091 https://reactome.org/PathwayBrowser/#/R-MMU-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Mus musculus 57945 R-MMU-5696101 https://reactome.org/PathwayBrowser/#/R-MMU-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Mus musculus 57945 R-MMU-5696457 https://reactome.org/PathwayBrowser/#/R-MMU-5696457 BDH2 dehydrogenates 3HBA IEA Mus musculus 57945 R-MMU-6783939 https://reactome.org/PathwayBrowser/#/R-MMU-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 57945 R-MMU-6784399 https://reactome.org/PathwayBrowser/#/R-MMU-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Mus musculus 57945 R-MMU-6797955 https://reactome.org/PathwayBrowser/#/R-MMU-6797955 ALDH7A1 oxidises BETALD to BET IEA Mus musculus 57945 R-MMU-6801328 https://reactome.org/PathwayBrowser/#/R-MMU-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Mus musculus 57945 R-MMU-6806831 https://reactome.org/PathwayBrowser/#/R-MMU-6806831 CYB5Rs reduce MetHb to HbA IEA Mus musculus 57945 R-MMU-6807826 https://reactome.org/PathwayBrowser/#/R-MMU-6807826 LDHAL6B reduces PYR to LACT IEA Mus musculus 57945 R-MMU-6808464 https://reactome.org/PathwayBrowser/#/R-MMU-6808464 ALDH3B2 oxidises HXAL to PALM IEA Mus musculus 57945 R-MMU-6809264 https://reactome.org/PathwayBrowser/#/R-MMU-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 57945 R-MMU-6809287 https://reactome.org/PathwayBrowser/#/R-MMU-6809287 NUDT12 hydrolyses NADH to NMNH IEA Mus musculus 57945 R-MMU-6813749 https://reactome.org/PathwayBrowser/#/R-MMU-6813749 ALDH1A1 oxidises GA to DGA IEA Mus musculus 57945 R-MMU-70449 https://reactome.org/PathwayBrowser/#/R-MMU-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Mus musculus 57945 R-MMU-70482 https://reactome.org/PathwayBrowser/#/R-MMU-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Mus musculus 57945 R-MMU-70510 https://reactome.org/PathwayBrowser/#/R-MMU-70510 LDH tetramer oxidises LACT to PYR IEA Mus musculus 57945 R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Mus musculus 57945 R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Mus musculus 57945 R-MMU-70664 https://reactome.org/PathwayBrowser/#/R-MMU-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 57945 R-MMU-70679 https://reactome.org/PathwayBrowser/#/R-MMU-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Mus musculus 57945 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 57945 R-MMU-70837 https://reactome.org/PathwayBrowser/#/R-MMU-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Mus musculus 57945 R-MMU-70885 https://reactome.org/PathwayBrowser/#/R-MMU-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Mus musculus 57945 R-MMU-70893 https://reactome.org/PathwayBrowser/#/R-MMU-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Mus musculus 57945 R-MMU-70940 https://reactome.org/PathwayBrowser/#/R-MMU-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Mus musculus 57945 R-MMU-70941 https://reactome.org/PathwayBrowser/#/R-MMU-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Mus musculus 57945 R-MMU-70967 https://reactome.org/PathwayBrowser/#/R-MMU-70967 IDH3 complex decarboxylates isocitrate IEA Mus musculus 57945 R-MMU-70979 https://reactome.org/PathwayBrowser/#/R-MMU-70979 MDH2 dimer dehydrogenates MAL IEA Mus musculus 57945 R-MMU-71037 https://reactome.org/PathwayBrowser/#/R-MMU-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Mus musculus 57945 R-MMU-71130 https://reactome.org/PathwayBrowser/#/R-MMU-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Mus musculus 57945 R-MMU-71260 https://reactome.org/PathwayBrowser/#/R-MMU-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Mus musculus 57945 R-MMU-71401 https://reactome.org/PathwayBrowser/#/R-MMU-71401 OGDH dimer decarboxylates 2-OG IEA Mus musculus 57945 R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 57945 R-MMU-71707 https://reactome.org/PathwayBrowser/#/R-MMU-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Mus musculus 57945 R-MMU-71723 https://reactome.org/PathwayBrowser/#/R-MMU-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Mus musculus 57945 R-MMU-71849 https://reactome.org/PathwayBrowser/#/R-MMU-71849 LDH tetramer reduces PYR to LACT IEA Mus musculus 57945 R-MMU-73794 https://reactome.org/PathwayBrowser/#/R-MMU-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Mus musculus 57945 R-MMU-73912 https://reactome.org/PathwayBrowser/#/R-MMU-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Mus musculus 57945 R-MMU-73920 https://reactome.org/PathwayBrowser/#/R-MMU-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Mus musculus 57945 R-MMU-75889 https://reactome.org/PathwayBrowser/#/R-MMU-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Mus musculus 57945 R-MMU-77254 https://reactome.org/PathwayBrowser/#/R-MMU-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Mus musculus 57945 R-MMU-77283 https://reactome.org/PathwayBrowser/#/R-MMU-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Mus musculus 57945 R-MMU-77303 https://reactome.org/PathwayBrowser/#/R-MMU-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Mus musculus 57945 R-MMU-77312 https://reactome.org/PathwayBrowser/#/R-MMU-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Mus musculus 57945 R-MMU-77323 https://reactome.org/PathwayBrowser/#/R-MMU-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Mus musculus 57945 R-MMU-77331 https://reactome.org/PathwayBrowser/#/R-MMU-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Mus musculus 57945 R-MMU-77342 https://reactome.org/PathwayBrowser/#/R-MMU-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Mus musculus 57945 R-MMU-888548 https://reactome.org/PathwayBrowser/#/R-MMU-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Mus musculus 57945 R-MMU-8936442 https://reactome.org/PathwayBrowser/#/R-MMU-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Mus musculus 57945 R-MMU-8956439 https://reactome.org/PathwayBrowser/#/R-MMU-8956439 Retsat reduces atROL to at-13,14-dhROL TAS Mus musculus 57945 R-MMU-9012268 https://reactome.org/PathwayBrowser/#/R-MMU-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Mus musculus 57945 R-MMU-9023968 https://reactome.org/PathwayBrowser/#/R-MMU-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Mus musculus 57945 R-MMU-9024766 https://reactome.org/PathwayBrowser/#/R-MMU-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Mus musculus 57945 R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 57945 R-MMU-9727349 https://reactome.org/PathwayBrowser/#/R-MMU-9727349 XDH dehydrogenates xanthine to form urate IEA Mus musculus 57945 R-MMU-9748945 https://reactome.org/PathwayBrowser/#/R-MMU-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Mus musculus 57945 R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 57945 R-MMU-9759549 https://reactome.org/PathwayBrowser/#/R-MMU-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Mus musculus 57945 R-MMU-977348 https://reactome.org/PathwayBrowser/#/R-MMU-977348 PHGDH tetramer dehydrogenates 3PG IEA Mus musculus 57945 R-MMU-9853499 https://reactome.org/PathwayBrowser/#/R-MMU-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 57945 R-MMU-9856871 https://reactome.org/PathwayBrowser/#/R-MMU-9856871 MDH1 reduces OA IEA Mus musculus 57945 R-MMU-9861616 https://reactome.org/PathwayBrowser/#/R-MMU-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 57945 R-MTU-879245 https://reactome.org/PathwayBrowser/#/R-MTU-879245 mycothiol binds formaldehyde and is dehydrogenated TAS Mycobacterium tuberculosis 57945 R-MTU-964914 https://reactome.org/PathwayBrowser/#/R-MTU-964914 DHQ from DAHP dephosphorylation TAS Mycobacterium tuberculosis 57945 R-OCU-2161568 https://reactome.org/PathwayBrowser/#/R-OCU-2161568 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD TAS Oryctolagus cuniculus 57945 R-PFA-204617 https://reactome.org/PathwayBrowser/#/R-PFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Plasmodium falciparum 57945 R-PFA-204647 https://reactome.org/PathwayBrowser/#/R-PFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Plasmodium falciparum 57945 R-PFA-204662 https://reactome.org/PathwayBrowser/#/R-PFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Plasmodium falciparum 57945 R-PFA-450971 https://reactome.org/PathwayBrowser/#/R-PFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Plasmodium falciparum 57945 R-PFA-5694018 https://reactome.org/PathwayBrowser/#/R-PFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Plasmodium falciparum 57945 R-PFA-6783939 https://reactome.org/PathwayBrowser/#/R-PFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 57945 R-PFA-6801328 https://reactome.org/PathwayBrowser/#/R-PFA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Plasmodium falciparum 57945 R-PFA-70449 https://reactome.org/PathwayBrowser/#/R-PFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Plasmodium falciparum 57945 R-PFA-70482 https://reactome.org/PathwayBrowser/#/R-PFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Plasmodium falciparum 57945 R-PFA-70664 https://reactome.org/PathwayBrowser/#/R-PFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 57945 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 57945 R-PFA-70979 https://reactome.org/PathwayBrowser/#/R-PFA-70979 MDH2 dimer dehydrogenates MAL IEA Plasmodium falciparum 57945 R-PFA-71401 https://reactome.org/PathwayBrowser/#/R-PFA-71401 OGDH dimer decarboxylates 2-OG IEA Plasmodium falciparum 57945 R-PFA-73794 https://reactome.org/PathwayBrowser/#/R-PFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Plasmodium falciparum 57945 R-PFA-75889 https://reactome.org/PathwayBrowser/#/R-PFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Plasmodium falciparum 57945 R-PFA-9748945 https://reactome.org/PathwayBrowser/#/R-PFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Plasmodium falciparum 57945 R-PFA-9853499 https://reactome.org/PathwayBrowser/#/R-PFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Plasmodium falciparum 57945 R-RNO-109343 https://reactome.org/PathwayBrowser/#/R-RNO-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Rattus norvegicus 57945 R-RNO-1614362 https://reactome.org/PathwayBrowser/#/R-RNO-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Rattus norvegicus 57945 R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Rattus norvegicus 57945 R-RNO-173597 https://reactome.org/PathwayBrowser/#/R-RNO-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Rattus norvegicus 57945 R-RNO-192097 https://reactome.org/PathwayBrowser/#/R-RNO-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Rattus norvegicus 57945 R-RNO-193073 https://reactome.org/PathwayBrowser/#/R-RNO-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Rattus norvegicus 57945 R-RNO-193455 https://reactome.org/PathwayBrowser/#/R-RNO-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 57945 R-RNO-193508 https://reactome.org/PathwayBrowser/#/R-RNO-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 57945 R-RNO-193789 https://reactome.org/PathwayBrowser/#/R-RNO-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 57945 R-RNO-193816 https://reactome.org/PathwayBrowser/#/R-RNO-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Rattus norvegicus 57945 R-RNO-194642 https://reactome.org/PathwayBrowser/#/R-RNO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Rattus norvegicus 57945 R-RNO-194718 https://reactome.org/PathwayBrowser/#/R-RNO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Rattus norvegicus 57945 R-RNO-196350 https://reactome.org/PathwayBrowser/#/R-RNO-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Rattus norvegicus 57945 R-RNO-196372 https://reactome.org/PathwayBrowser/#/R-RNO-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Rattus norvegicus 57945 R-RNO-198824 https://reactome.org/PathwayBrowser/#/R-RNO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Rattus norvegicus 57945 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 57945 R-RNO-2046084 https://reactome.org/PathwayBrowser/#/R-RNO-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Rattus norvegicus 57945 R-RNO-2046089 https://reactome.org/PathwayBrowser/#/R-RNO-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Rattus norvegicus 57945 R-RNO-2046091 https://reactome.org/PathwayBrowser/#/R-RNO-2046091 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA TAS Rattus norvegicus 57945 R-RNO-2046092 https://reactome.org/PathwayBrowser/#/R-RNO-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Rattus norvegicus 57945 R-RNO-2046096 https://reactome.org/PathwayBrowser/#/R-RNO-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Rattus norvegicus 57945 R-RNO-2046097 https://reactome.org/PathwayBrowser/#/R-RNO-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 57945 R-RNO-204617 https://reactome.org/PathwayBrowser/#/R-RNO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Rattus norvegicus 57945 R-RNO-204647 https://reactome.org/PathwayBrowser/#/R-RNO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Rattus norvegicus 57945 R-RNO-204662 https://reactome.org/PathwayBrowser/#/R-RNO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Rattus norvegicus 57945 R-RNO-2161779 https://reactome.org/PathwayBrowser/#/R-RNO-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Rattus norvegicus 57945 R-RNO-2162078 https://reactome.org/PathwayBrowser/#/R-RNO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Rattus norvegicus 57945 R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 57945 R-RNO-380608 https://reactome.org/PathwayBrowser/#/R-RNO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Rattus norvegicus 57945 R-RNO-389609 https://reactome.org/PathwayBrowser/#/R-RNO-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Rattus norvegicus 57945 R-RNO-389995 https://reactome.org/PathwayBrowser/#/R-RNO-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Rattus norvegicus 57945 R-RNO-390251 https://reactome.org/PathwayBrowser/#/R-RNO-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 57945 R-RNO-450971 https://reactome.org/PathwayBrowser/#/R-RNO-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Rattus norvegicus 57945 R-RNO-508369 https://reactome.org/PathwayBrowser/#/R-RNO-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Rattus norvegicus 57945 R-RNO-508473 https://reactome.org/PathwayBrowser/#/R-RNO-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Rattus norvegicus 57945 R-RNO-5362518 https://reactome.org/PathwayBrowser/#/R-RNO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Rattus norvegicus 57945 R-RNO-5362522 https://reactome.org/PathwayBrowser/#/R-RNO-5362522 ALDHs oxidise atRAL to atRA IEA Rattus norvegicus 57945 R-RNO-5362564 https://reactome.org/PathwayBrowser/#/R-RNO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Rattus norvegicus 57945 R-RNO-5362721 https://reactome.org/PathwayBrowser/#/R-RNO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 57945 R-RNO-5652195 https://reactome.org/PathwayBrowser/#/R-RNO-5652195 SORD oxidizes D-sorbitol to Fru IEA Rattus norvegicus 57945 R-RNO-5661290 https://reactome.org/PathwayBrowser/#/R-RNO-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Rattus norvegicus 57945 R-RNO-5662471 https://reactome.org/PathwayBrowser/#/R-RNO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Rattus norvegicus 57945 R-RNO-5692237 https://reactome.org/PathwayBrowser/#/R-RNO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Rattus norvegicus 57945 R-RNO-5692261 https://reactome.org/PathwayBrowser/#/R-RNO-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Rattus norvegicus 57945 R-RNO-5694018 https://reactome.org/PathwayBrowser/#/R-RNO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Rattus norvegicus 57945 R-RNO-5696080 https://reactome.org/PathwayBrowser/#/R-RNO-5696080 ALDH3B1 oxidises HXAL to PALM IEA Rattus norvegicus 57945 R-RNO-5696091 https://reactome.org/PathwayBrowser/#/R-RNO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Rattus norvegicus 57945 R-RNO-5696101 https://reactome.org/PathwayBrowser/#/R-RNO-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Rattus norvegicus 57945 R-RNO-5696457 https://reactome.org/PathwayBrowser/#/R-RNO-5696457 BDH2 dehydrogenates 3HBA IEA Rattus norvegicus 57945 R-RNO-6783939 https://reactome.org/PathwayBrowser/#/R-RNO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 57945 R-RNO-6784399 https://reactome.org/PathwayBrowser/#/R-RNO-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Rattus norvegicus 57945 R-RNO-6797955 https://reactome.org/PathwayBrowser/#/R-RNO-6797955 ALDH7A1 oxidises BETALD to BET IEA Rattus norvegicus 57945 R-RNO-6801328 https://reactome.org/PathwayBrowser/#/R-RNO-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Rattus norvegicus 57945 R-RNO-6806831 https://reactome.org/PathwayBrowser/#/R-RNO-6806831 CYB5Rs reduce MetHb to HbA IEA Rattus norvegicus 57945 R-RNO-6807826 https://reactome.org/PathwayBrowser/#/R-RNO-6807826 LDHAL6B reduces PYR to LACT IEA Rattus norvegicus 57945 R-RNO-6808464 https://reactome.org/PathwayBrowser/#/R-RNO-6808464 ALDH3B2 oxidises HXAL to PALM IEA Rattus norvegicus 57945 R-RNO-6809264 https://reactome.org/PathwayBrowser/#/R-RNO-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 57945 R-RNO-6809287 https://reactome.org/PathwayBrowser/#/R-RNO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Rattus norvegicus 57945 R-RNO-6813749 https://reactome.org/PathwayBrowser/#/R-RNO-6813749 ALDH1A1 oxidises GA to DGA IEA Rattus norvegicus 57945 R-RNO-70449 https://reactome.org/PathwayBrowser/#/R-RNO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Rattus norvegicus 57945 R-RNO-70482 https://reactome.org/PathwayBrowser/#/R-RNO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Rattus norvegicus 57945 R-RNO-70510 https://reactome.org/PathwayBrowser/#/R-RNO-70510 LDH tetramer oxidises LACT to PYR IEA Rattus norvegicus 57945 R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Rattus norvegicus 57945 R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Rattus norvegicus 57945 R-RNO-70664 https://reactome.org/PathwayBrowser/#/R-RNO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 57945 R-RNO-70679 https://reactome.org/PathwayBrowser/#/R-RNO-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Rattus norvegicus 57945 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 57945 R-RNO-70837 https://reactome.org/PathwayBrowser/#/R-RNO-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Rattus norvegicus 57945 R-RNO-70885 https://reactome.org/PathwayBrowser/#/R-RNO-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Rattus norvegicus 57945 R-RNO-70893 https://reactome.org/PathwayBrowser/#/R-RNO-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 57945 R-RNO-70940 https://reactome.org/PathwayBrowser/#/R-RNO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Rattus norvegicus 57945 R-RNO-70941 https://reactome.org/PathwayBrowser/#/R-RNO-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Rattus norvegicus 57945 R-RNO-70967 https://reactome.org/PathwayBrowser/#/R-RNO-70967 IDH3 complex decarboxylates isocitrate IEA Rattus norvegicus 57945 R-RNO-70979 https://reactome.org/PathwayBrowser/#/R-RNO-70979 MDH2 dimer dehydrogenates MAL IEA Rattus norvegicus 57945 R-RNO-71037 https://reactome.org/PathwayBrowser/#/R-RNO-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 57945 R-RNO-71130 https://reactome.org/PathwayBrowser/#/R-RNO-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Rattus norvegicus 57945 R-RNO-71260 https://reactome.org/PathwayBrowser/#/R-RNO-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Rattus norvegicus 57945 R-RNO-71401 https://reactome.org/PathwayBrowser/#/R-RNO-71401 OGDH dimer decarboxylates 2-OG IEA Rattus norvegicus 57945 R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 57945 R-RNO-71707 https://reactome.org/PathwayBrowser/#/R-RNO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Rattus norvegicus 57945 R-RNO-71723 https://reactome.org/PathwayBrowser/#/R-RNO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Rattus norvegicus 57945 R-RNO-71849 https://reactome.org/PathwayBrowser/#/R-RNO-71849 LDH tetramer reduces PYR to LACT IEA Rattus norvegicus 57945 R-RNO-73794 https://reactome.org/PathwayBrowser/#/R-RNO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Rattus norvegicus 57945 R-RNO-73912 https://reactome.org/PathwayBrowser/#/R-RNO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Rattus norvegicus 57945 R-RNO-73920 https://reactome.org/PathwayBrowser/#/R-RNO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Rattus norvegicus 57945 R-RNO-75889 https://reactome.org/PathwayBrowser/#/R-RNO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Rattus norvegicus 57945 R-RNO-77254 https://reactome.org/PathwayBrowser/#/R-RNO-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Rattus norvegicus 57945 R-RNO-77283 https://reactome.org/PathwayBrowser/#/R-RNO-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Rattus norvegicus 57945 R-RNO-77303 https://reactome.org/PathwayBrowser/#/R-RNO-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Rattus norvegicus 57945 R-RNO-77312 https://reactome.org/PathwayBrowser/#/R-RNO-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Rattus norvegicus 57945 R-RNO-77323 https://reactome.org/PathwayBrowser/#/R-RNO-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Rattus norvegicus 57945 R-RNO-77331 https://reactome.org/PathwayBrowser/#/R-RNO-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Rattus norvegicus 57945 R-RNO-77342 https://reactome.org/PathwayBrowser/#/R-RNO-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Rattus norvegicus 57945 R-RNO-888548 https://reactome.org/PathwayBrowser/#/R-RNO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Rattus norvegicus 57945 R-RNO-8936442 https://reactome.org/PathwayBrowser/#/R-RNO-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Rattus norvegicus 57945 R-RNO-9012268 https://reactome.org/PathwayBrowser/#/R-RNO-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 57945 R-RNO-9023968 https://reactome.org/PathwayBrowser/#/R-RNO-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Rattus norvegicus 57945 R-RNO-9024766 https://reactome.org/PathwayBrowser/#/R-RNO-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Rattus norvegicus 57945 R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 57945 R-RNO-9727349 https://reactome.org/PathwayBrowser/#/R-RNO-9727349 XDH dehydrogenates xanthine to form urate IEA Rattus norvegicus 57945 R-RNO-9748945 https://reactome.org/PathwayBrowser/#/R-RNO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Rattus norvegicus 57945 R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 57945 R-RNO-9759549 https://reactome.org/PathwayBrowser/#/R-RNO-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Rattus norvegicus 57945 R-RNO-977348 https://reactome.org/PathwayBrowser/#/R-RNO-977348 PHGDH tetramer dehydrogenates 3PG IEA Rattus norvegicus 57945 R-RNO-9853499 https://reactome.org/PathwayBrowser/#/R-RNO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 57945 R-RNO-9856871 https://reactome.org/PathwayBrowser/#/R-RNO-9856871 MDH1 reduces OA IEA Rattus norvegicus 57945 R-RNO-9861616 https://reactome.org/PathwayBrowser/#/R-RNO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 57945 R-SCE-194642 https://reactome.org/PathwayBrowser/#/R-SCE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Saccharomyces cerevisiae 57945 R-SCE-194718 https://reactome.org/PathwayBrowser/#/R-SCE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Saccharomyces cerevisiae 57945 R-SCE-198824 https://reactome.org/PathwayBrowser/#/R-SCE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Saccharomyces cerevisiae 57945 R-SCE-204617 https://reactome.org/PathwayBrowser/#/R-SCE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Saccharomyces cerevisiae 57945 R-SCE-204647 https://reactome.org/PathwayBrowser/#/R-SCE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Saccharomyces cerevisiae 57945 R-SCE-204662 https://reactome.org/PathwayBrowser/#/R-SCE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Saccharomyces cerevisiae 57945 R-SCE-2162078 https://reactome.org/PathwayBrowser/#/R-SCE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Saccharomyces cerevisiae 57945 R-SCE-2162194 https://reactome.org/PathwayBrowser/#/R-SCE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Saccharomyces cerevisiae 57945 R-SCE-380608 https://reactome.org/PathwayBrowser/#/R-SCE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Saccharomyces cerevisiae 57945 R-SCE-389609 https://reactome.org/PathwayBrowser/#/R-SCE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Saccharomyces cerevisiae 57945 R-SCE-5362518 https://reactome.org/PathwayBrowser/#/R-SCE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Saccharomyces cerevisiae 57945 R-SCE-5362522 https://reactome.org/PathwayBrowser/#/R-SCE-5362522 ALDHs oxidise atRAL to atRA IEA Saccharomyces cerevisiae 57945 R-SCE-5362564 https://reactome.org/PathwayBrowser/#/R-SCE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Saccharomyces cerevisiae 57945 R-SCE-5652195 https://reactome.org/PathwayBrowser/#/R-SCE-5652195 SORD oxidizes D-sorbitol to Fru IEA Saccharomyces cerevisiae 57945 R-SCE-5662471 https://reactome.org/PathwayBrowser/#/R-SCE-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Saccharomyces cerevisiae 57945 R-SCE-5692237 https://reactome.org/PathwayBrowser/#/R-SCE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Saccharomyces cerevisiae 57945 R-SCE-5692261 https://reactome.org/PathwayBrowser/#/R-SCE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Saccharomyces cerevisiae 57945 R-SCE-5694018 https://reactome.org/PathwayBrowser/#/R-SCE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Saccharomyces cerevisiae 57945 R-SCE-5696080 https://reactome.org/PathwayBrowser/#/R-SCE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 57945 R-SCE-5696091 https://reactome.org/PathwayBrowser/#/R-SCE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Saccharomyces cerevisiae 57945 R-SCE-6783939 https://reactome.org/PathwayBrowser/#/R-SCE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 57945 R-SCE-6790127 https://reactome.org/PathwayBrowser/#/R-SCE-6790127 SMM1 (DUS2) reduces uridine-20 to dihydrouridine in tRNA(Leu) TAS Saccharomyces cerevisiae 57945 R-SCE-6801328 https://reactome.org/PathwayBrowser/#/R-SCE-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Saccharomyces cerevisiae 57945 R-SCE-6808464 https://reactome.org/PathwayBrowser/#/R-SCE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 57945 R-SCE-6809287 https://reactome.org/PathwayBrowser/#/R-SCE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Saccharomyces cerevisiae 57945 R-SCE-6813749 https://reactome.org/PathwayBrowser/#/R-SCE-6813749 ALDH1A1 oxidises GA to DGA IEA Saccharomyces cerevisiae 57945 R-SCE-70449 https://reactome.org/PathwayBrowser/#/R-SCE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Saccharomyces cerevisiae 57945 R-SCE-70482 https://reactome.org/PathwayBrowser/#/R-SCE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Saccharomyces cerevisiae 57945 R-SCE-70664 https://reactome.org/PathwayBrowser/#/R-SCE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 57945 R-SCE-70940 https://reactome.org/PathwayBrowser/#/R-SCE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Saccharomyces cerevisiae 57945 R-SCE-70967 https://reactome.org/PathwayBrowser/#/R-SCE-70967 IDH3 complex decarboxylates isocitrate IEA Saccharomyces cerevisiae 57945 R-SCE-70979 https://reactome.org/PathwayBrowser/#/R-SCE-70979 MDH2 dimer dehydrogenates MAL IEA Saccharomyces cerevisiae 57945 R-SCE-71401 https://reactome.org/PathwayBrowser/#/R-SCE-71401 OGDH dimer decarboxylates 2-OG IEA Saccharomyces cerevisiae 57945 R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 57945 R-SCE-71707 https://reactome.org/PathwayBrowser/#/R-SCE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Saccharomyces cerevisiae 57945 R-SCE-71723 https://reactome.org/PathwayBrowser/#/R-SCE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Saccharomyces cerevisiae 57945 R-SCE-73794 https://reactome.org/PathwayBrowser/#/R-SCE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Saccharomyces cerevisiae 57945 R-SCE-75889 https://reactome.org/PathwayBrowser/#/R-SCE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Saccharomyces cerevisiae 57945 R-SCE-888548 https://reactome.org/PathwayBrowser/#/R-SCE-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Saccharomyces cerevisiae 57945 R-SCE-9748945 https://reactome.org/PathwayBrowser/#/R-SCE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Saccharomyces cerevisiae 57945 R-SCE-9853499 https://reactome.org/PathwayBrowser/#/R-SCE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 57945 R-SCE-9861616 https://reactome.org/PathwayBrowser/#/R-SCE-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 57945 R-SPO-194642 https://reactome.org/PathwayBrowser/#/R-SPO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Schizosaccharomyces pombe 57945 R-SPO-194718 https://reactome.org/PathwayBrowser/#/R-SPO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Schizosaccharomyces pombe 57945 R-SPO-198824 https://reactome.org/PathwayBrowser/#/R-SPO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Schizosaccharomyces pombe 57945 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 57945 R-SPO-204617 https://reactome.org/PathwayBrowser/#/R-SPO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Schizosaccharomyces pombe 57945 R-SPO-204647 https://reactome.org/PathwayBrowser/#/R-SPO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Schizosaccharomyces pombe 57945 R-SPO-204662 https://reactome.org/PathwayBrowser/#/R-SPO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Schizosaccharomyces pombe 57945 R-SPO-2162078 https://reactome.org/PathwayBrowser/#/R-SPO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Schizosaccharomyces pombe 57945 R-SPO-2162194 https://reactome.org/PathwayBrowser/#/R-SPO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Schizosaccharomyces pombe 57945 R-SPO-380608 https://reactome.org/PathwayBrowser/#/R-SPO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Schizosaccharomyces pombe 57945 R-SPO-5362518 https://reactome.org/PathwayBrowser/#/R-SPO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Schizosaccharomyces pombe 57945 R-SPO-5362522 https://reactome.org/PathwayBrowser/#/R-SPO-5362522 ALDHs oxidise atRAL to atRA IEA Schizosaccharomyces pombe 57945 R-SPO-5362564 https://reactome.org/PathwayBrowser/#/R-SPO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Schizosaccharomyces pombe 57945 R-SPO-5362721 https://reactome.org/PathwayBrowser/#/R-SPO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Schizosaccharomyces pombe 57945 R-SPO-5652195 https://reactome.org/PathwayBrowser/#/R-SPO-5652195 SORD oxidizes D-sorbitol to Fru IEA Schizosaccharomyces pombe 57945 R-SPO-5662471 https://reactome.org/PathwayBrowser/#/R-SPO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Schizosaccharomyces pombe 57945 R-SPO-5692237 https://reactome.org/PathwayBrowser/#/R-SPO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Schizosaccharomyces pombe 57945 R-SPO-5694018 https://reactome.org/PathwayBrowser/#/R-SPO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Schizosaccharomyces pombe 57945 R-SPO-5696091 https://reactome.org/PathwayBrowser/#/R-SPO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Schizosaccharomyces pombe 57945 R-SPO-6783939 https://reactome.org/PathwayBrowser/#/R-SPO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 57945 R-SPO-6801328 https://reactome.org/PathwayBrowser/#/R-SPO-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Schizosaccharomyces pombe 57945 R-SPO-6809287 https://reactome.org/PathwayBrowser/#/R-SPO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Schizosaccharomyces pombe 57945 R-SPO-6813749 https://reactome.org/PathwayBrowser/#/R-SPO-6813749 ALDH1A1 oxidises GA to DGA IEA Schizosaccharomyces pombe 57945 R-SPO-70449 https://reactome.org/PathwayBrowser/#/R-SPO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Schizosaccharomyces pombe 57945 R-SPO-70482 https://reactome.org/PathwayBrowser/#/R-SPO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Schizosaccharomyces pombe 57945 R-SPO-70664 https://reactome.org/PathwayBrowser/#/R-SPO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 57945 R-SPO-70940 https://reactome.org/PathwayBrowser/#/R-SPO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Schizosaccharomyces pombe 57945 R-SPO-70967 https://reactome.org/PathwayBrowser/#/R-SPO-70967 IDH3 complex decarboxylates isocitrate IEA Schizosaccharomyces pombe 57945 R-SPO-70979 https://reactome.org/PathwayBrowser/#/R-SPO-70979 MDH2 dimer dehydrogenates MAL IEA Schizosaccharomyces pombe 57945 R-SPO-71401 https://reactome.org/PathwayBrowser/#/R-SPO-71401 OGDH dimer decarboxylates 2-OG IEA Schizosaccharomyces pombe 57945 R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 57945 R-SPO-71707 https://reactome.org/PathwayBrowser/#/R-SPO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Schizosaccharomyces pombe 57945 R-SPO-71723 https://reactome.org/PathwayBrowser/#/R-SPO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Schizosaccharomyces pombe 57945 R-SPO-73794 https://reactome.org/PathwayBrowser/#/R-SPO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Schizosaccharomyces pombe 57945 R-SPO-73912 https://reactome.org/PathwayBrowser/#/R-SPO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Schizosaccharomyces pombe 57945 R-SPO-73920 https://reactome.org/PathwayBrowser/#/R-SPO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Schizosaccharomyces pombe 57945 R-SPO-75889 https://reactome.org/PathwayBrowser/#/R-SPO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Schizosaccharomyces pombe 57945 R-SPO-888548 https://reactome.org/PathwayBrowser/#/R-SPO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Schizosaccharomyces pombe 57945 R-SPO-9748945 https://reactome.org/PathwayBrowser/#/R-SPO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Schizosaccharomyces pombe 57945 R-SPO-9853499 https://reactome.org/PathwayBrowser/#/R-SPO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 57945 R-SPO-9861616 https://reactome.org/PathwayBrowser/#/R-SPO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 57945 R-SSC-109343 https://reactome.org/PathwayBrowser/#/R-SSC-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Sus scrofa 57945 R-SSC-1614362 https://reactome.org/PathwayBrowser/#/R-SSC-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Sus scrofa 57945 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Sus scrofa 57945 R-SSC-173597 https://reactome.org/PathwayBrowser/#/R-SSC-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Sus scrofa 57945 R-SSC-192097 https://reactome.org/PathwayBrowser/#/R-SSC-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Sus scrofa 57945 R-SSC-193073 https://reactome.org/PathwayBrowser/#/R-SSC-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Sus scrofa 57945 R-SSC-193789 https://reactome.org/PathwayBrowser/#/R-SSC-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Sus scrofa 57945 R-SSC-193816 https://reactome.org/PathwayBrowser/#/R-SSC-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Sus scrofa 57945 R-SSC-194642 https://reactome.org/PathwayBrowser/#/R-SSC-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Sus scrofa 57945 R-SSC-194718 https://reactome.org/PathwayBrowser/#/R-SSC-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Sus scrofa 57945 R-SSC-196350 https://reactome.org/PathwayBrowser/#/R-SSC-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Sus scrofa 57945 R-SSC-196372 https://reactome.org/PathwayBrowser/#/R-SSC-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Sus scrofa 57945 R-SSC-198824 https://reactome.org/PathwayBrowser/#/R-SSC-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Sus scrofa 57945 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 57945 R-SSC-2046084 https://reactome.org/PathwayBrowser/#/R-SSC-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Sus scrofa 57945 R-SSC-2046089 https://reactome.org/PathwayBrowser/#/R-SSC-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Sus scrofa 57945 R-SSC-2046092 https://reactome.org/PathwayBrowser/#/R-SSC-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Sus scrofa 57945 R-SSC-2046096 https://reactome.org/PathwayBrowser/#/R-SSC-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Sus scrofa 57945 R-SSC-2046097 https://reactome.org/PathwayBrowser/#/R-SSC-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 57945 R-SSC-204617 https://reactome.org/PathwayBrowser/#/R-SSC-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Sus scrofa 57945 R-SSC-204647 https://reactome.org/PathwayBrowser/#/R-SSC-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Sus scrofa 57945 R-SSC-204662 https://reactome.org/PathwayBrowser/#/R-SSC-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Sus scrofa 57945 R-SSC-2161779 https://reactome.org/PathwayBrowser/#/R-SSC-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Sus scrofa 57945 R-SSC-2162078 https://reactome.org/PathwayBrowser/#/R-SSC-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Sus scrofa 57945 R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa 57945 R-SSC-2454081 https://reactome.org/PathwayBrowser/#/R-SSC-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Sus scrofa 57945 R-SSC-380608 https://reactome.org/PathwayBrowser/#/R-SSC-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Sus scrofa 57945 R-SSC-389609 https://reactome.org/PathwayBrowser/#/R-SSC-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Sus scrofa 57945 R-SSC-508369 https://reactome.org/PathwayBrowser/#/R-SSC-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Sus scrofa 57945 R-SSC-508473 https://reactome.org/PathwayBrowser/#/R-SSC-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Sus scrofa 57945 R-SSC-5362518 https://reactome.org/PathwayBrowser/#/R-SSC-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Sus scrofa 57945 R-SSC-5362522 https://reactome.org/PathwayBrowser/#/R-SSC-5362522 ALDHs oxidise atRAL to atRA IEA Sus scrofa 57945 R-SSC-5362564 https://reactome.org/PathwayBrowser/#/R-SSC-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Sus scrofa 57945 R-SSC-5362721 https://reactome.org/PathwayBrowser/#/R-SSC-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Sus scrofa 57945 R-SSC-5652195 https://reactome.org/PathwayBrowser/#/R-SSC-5652195 SORD oxidizes D-sorbitol to Fru IEA Sus scrofa 57945 R-SSC-5661290 https://reactome.org/PathwayBrowser/#/R-SSC-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Sus scrofa 57945 R-SSC-5662471 https://reactome.org/PathwayBrowser/#/R-SSC-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Sus scrofa 57945 R-SSC-5692237 https://reactome.org/PathwayBrowser/#/R-SSC-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Sus scrofa 57945 R-SSC-5692261 https://reactome.org/PathwayBrowser/#/R-SSC-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Sus scrofa 57945 R-SSC-5694018 https://reactome.org/PathwayBrowser/#/R-SSC-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Sus scrofa 57945 R-SSC-5696080 https://reactome.org/PathwayBrowser/#/R-SSC-5696080 ALDH3B1 oxidises HXAL to PALM IEA Sus scrofa 57945 R-SSC-5696091 https://reactome.org/PathwayBrowser/#/R-SSC-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Sus scrofa 57945 R-SSC-5696101 https://reactome.org/PathwayBrowser/#/R-SSC-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Sus scrofa 57945 R-SSC-5696457 https://reactome.org/PathwayBrowser/#/R-SSC-5696457 BDH2 dehydrogenates 3HBA IEA Sus scrofa 57945 R-SSC-6783939 https://reactome.org/PathwayBrowser/#/R-SSC-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 57945 R-SSC-6784399 https://reactome.org/PathwayBrowser/#/R-SSC-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Sus scrofa 57945 R-SSC-6797955 https://reactome.org/PathwayBrowser/#/R-SSC-6797955 ALDH7A1 oxidises BETALD to BET IEA Sus scrofa 57945 R-SSC-6801328 https://reactome.org/PathwayBrowser/#/R-SSC-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Sus scrofa 57945 R-SSC-6806831 https://reactome.org/PathwayBrowser/#/R-SSC-6806831 CYB5Rs reduce MetHb to HbA IEA Sus scrofa 57945 R-SSC-6808464 https://reactome.org/PathwayBrowser/#/R-SSC-6808464 ALDH3B2 oxidises HXAL to PALM IEA Sus scrofa 57945 R-SSC-6809264 https://reactome.org/PathwayBrowser/#/R-SSC-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Sus scrofa 57945 R-SSC-6809287 https://reactome.org/PathwayBrowser/#/R-SSC-6809287 NUDT12 hydrolyses NADH to NMNH IEA Sus scrofa 57945 R-SSC-6813749 https://reactome.org/PathwayBrowser/#/R-SSC-6813749 ALDH1A1 oxidises GA to DGA IEA Sus scrofa 57945 R-SSC-70449 https://reactome.org/PathwayBrowser/#/R-SSC-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Sus scrofa 57945 R-SSC-70482 https://reactome.org/PathwayBrowser/#/R-SSC-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Sus scrofa 57945 R-SSC-70510 https://reactome.org/PathwayBrowser/#/R-SSC-70510 LDH tetramer oxidises LACT to PYR IEA Sus scrofa 57945 R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Sus scrofa 57945 R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Sus scrofa 57945 R-SSC-70664 https://reactome.org/PathwayBrowser/#/R-SSC-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 57945 R-SSC-70679 https://reactome.org/PathwayBrowser/#/R-SSC-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Sus scrofa 57945 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 57945 R-SSC-70837 https://reactome.org/PathwayBrowser/#/R-SSC-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Sus scrofa 57945 R-SSC-70885 https://reactome.org/PathwayBrowser/#/R-SSC-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Sus scrofa 57945 R-SSC-70893 https://reactome.org/PathwayBrowser/#/R-SSC-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Sus scrofa 57945 R-SSC-70940 https://reactome.org/PathwayBrowser/#/R-SSC-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Sus scrofa 57945 R-SSC-70941 https://reactome.org/PathwayBrowser/#/R-SSC-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Sus scrofa 57945 R-SSC-70967 https://reactome.org/PathwayBrowser/#/R-SSC-70967 IDH3 complex decarboxylates isocitrate IEA Sus scrofa 57945 R-SSC-70979 https://reactome.org/PathwayBrowser/#/R-SSC-70979 MDH2 dimer dehydrogenates MAL IEA Sus scrofa 57945 R-SSC-71037 https://reactome.org/PathwayBrowser/#/R-SSC-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Sus scrofa 57945 R-SSC-71130 https://reactome.org/PathwayBrowser/#/R-SSC-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Sus scrofa 57945 R-SSC-71260 https://reactome.org/PathwayBrowser/#/R-SSC-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Sus scrofa 57945 R-SSC-71401 https://reactome.org/PathwayBrowser/#/R-SSC-71401 OGDH dimer decarboxylates 2-OG IEA Sus scrofa 57945 R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 57945 R-SSC-71707 https://reactome.org/PathwayBrowser/#/R-SSC-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Sus scrofa 57945 R-SSC-71723 https://reactome.org/PathwayBrowser/#/R-SSC-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Sus scrofa 57945 R-SSC-71849 https://reactome.org/PathwayBrowser/#/R-SSC-71849 LDH tetramer reduces PYR to LACT IEA Sus scrofa 57945 R-SSC-73794 https://reactome.org/PathwayBrowser/#/R-SSC-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Sus scrofa 57945 R-SSC-73912 https://reactome.org/PathwayBrowser/#/R-SSC-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Sus scrofa 57945 R-SSC-73920 https://reactome.org/PathwayBrowser/#/R-SSC-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Sus scrofa 57945 R-SSC-75889 https://reactome.org/PathwayBrowser/#/R-SSC-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Sus scrofa 57945 R-SSC-77254 https://reactome.org/PathwayBrowser/#/R-SSC-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Sus scrofa 57945 R-SSC-77283 https://reactome.org/PathwayBrowser/#/R-SSC-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Sus scrofa 57945 R-SSC-77303 https://reactome.org/PathwayBrowser/#/R-SSC-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Sus scrofa 57945 R-SSC-77312 https://reactome.org/PathwayBrowser/#/R-SSC-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Sus scrofa 57945 R-SSC-77323 https://reactome.org/PathwayBrowser/#/R-SSC-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Sus scrofa 57945 R-SSC-77331 https://reactome.org/PathwayBrowser/#/R-SSC-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Sus scrofa 57945 R-SSC-77342 https://reactome.org/PathwayBrowser/#/R-SSC-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Sus scrofa 57945 R-SSC-888548 https://reactome.org/PathwayBrowser/#/R-SSC-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Sus scrofa 57945 R-SSC-8936442 https://reactome.org/PathwayBrowser/#/R-SSC-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Sus scrofa 57945 R-SSC-9012268 https://reactome.org/PathwayBrowser/#/R-SSC-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Sus scrofa 57945 R-SSC-9023968 https://reactome.org/PathwayBrowser/#/R-SSC-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Sus scrofa 57945 R-SSC-9024766 https://reactome.org/PathwayBrowser/#/R-SSC-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Sus scrofa 57945 R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 57945 R-SSC-9727349 https://reactome.org/PathwayBrowser/#/R-SSC-9727349 XDH dehydrogenates xanthine to form urate IEA Sus scrofa 57945 R-SSC-9748945 https://reactome.org/PathwayBrowser/#/R-SSC-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Sus scrofa 57945 R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 57945 R-SSC-9759549 https://reactome.org/PathwayBrowser/#/R-SSC-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Sus scrofa 57945 R-SSC-977348 https://reactome.org/PathwayBrowser/#/R-SSC-977348 PHGDH tetramer dehydrogenates 3PG IEA Sus scrofa 57945 R-SSC-9853499 https://reactome.org/PathwayBrowser/#/R-SSC-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 57945 R-SSC-9856871 https://reactome.org/PathwayBrowser/#/R-SSC-9856871 MDH1 reduces OA IEA Sus scrofa 57945 R-SSC-9861616 https://reactome.org/PathwayBrowser/#/R-SSC-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 57945 R-XTR-109343 https://reactome.org/PathwayBrowser/#/R-XTR-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Xenopus tropicalis 57945 R-XTR-1614362 https://reactome.org/PathwayBrowser/#/R-XTR-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Xenopus tropicalis 57945 R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Xenopus tropicalis 57945 R-XTR-173597 https://reactome.org/PathwayBrowser/#/R-XTR-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Xenopus tropicalis 57945 R-XTR-192097 https://reactome.org/PathwayBrowser/#/R-XTR-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Xenopus tropicalis 57945 R-XTR-193789 https://reactome.org/PathwayBrowser/#/R-XTR-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 57945 R-XTR-193816 https://reactome.org/PathwayBrowser/#/R-XTR-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Xenopus tropicalis 57945 R-XTR-198824 https://reactome.org/PathwayBrowser/#/R-XTR-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Xenopus tropicalis 57945 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 57945 R-XTR-2046089 https://reactome.org/PathwayBrowser/#/R-XTR-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Xenopus tropicalis 57945 R-XTR-2046092 https://reactome.org/PathwayBrowser/#/R-XTR-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Xenopus tropicalis 57945 R-XTR-204617 https://reactome.org/PathwayBrowser/#/R-XTR-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Xenopus tropicalis 57945 R-XTR-204647 https://reactome.org/PathwayBrowser/#/R-XTR-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Xenopus tropicalis 57945 R-XTR-204662 https://reactome.org/PathwayBrowser/#/R-XTR-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Xenopus tropicalis 57945 R-XTR-2161779 https://reactome.org/PathwayBrowser/#/R-XTR-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Xenopus tropicalis 57945 R-XTR-2162078 https://reactome.org/PathwayBrowser/#/R-XTR-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Xenopus tropicalis 57945 R-XTR-2162194 https://reactome.org/PathwayBrowser/#/R-XTR-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Xenopus tropicalis 57945 R-XTR-2454081 https://reactome.org/PathwayBrowser/#/R-XTR-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Xenopus tropicalis 57945 R-XTR-380608 https://reactome.org/PathwayBrowser/#/R-XTR-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Xenopus tropicalis 57945 R-XTR-450971 https://reactome.org/PathwayBrowser/#/R-XTR-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Xenopus tropicalis 57945 R-XTR-508369 https://reactome.org/PathwayBrowser/#/R-XTR-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Xenopus tropicalis 57945 R-XTR-508473 https://reactome.org/PathwayBrowser/#/R-XTR-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Xenopus tropicalis 57945 R-XTR-5362518 https://reactome.org/PathwayBrowser/#/R-XTR-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Xenopus tropicalis 57945 R-XTR-5362522 https://reactome.org/PathwayBrowser/#/R-XTR-5362522 ALDHs oxidise atRAL to atRA IEA Xenopus tropicalis 57945 R-XTR-5362564 https://reactome.org/PathwayBrowser/#/R-XTR-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Xenopus tropicalis 57945 R-XTR-5362721 https://reactome.org/PathwayBrowser/#/R-XTR-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 57945 R-XTR-5652195 https://reactome.org/PathwayBrowser/#/R-XTR-5652195 SORD oxidizes D-sorbitol to Fru IEA Xenopus tropicalis 57945 R-XTR-5661290 https://reactome.org/PathwayBrowser/#/R-XTR-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Xenopus tropicalis 57945 R-XTR-5662471 https://reactome.org/PathwayBrowser/#/R-XTR-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Xenopus tropicalis 57945 R-XTR-5692237 https://reactome.org/PathwayBrowser/#/R-XTR-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Xenopus tropicalis 57945 R-XTR-5694018 https://reactome.org/PathwayBrowser/#/R-XTR-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Xenopus tropicalis 57945 R-XTR-5696080 https://reactome.org/PathwayBrowser/#/R-XTR-5696080 ALDH3B1 oxidises HXAL to PALM IEA Xenopus tropicalis 57945 R-XTR-5696091 https://reactome.org/PathwayBrowser/#/R-XTR-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Xenopus tropicalis 57945 R-XTR-5696101 https://reactome.org/PathwayBrowser/#/R-XTR-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Xenopus tropicalis 57945 R-XTR-6783939 https://reactome.org/PathwayBrowser/#/R-XTR-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 57945 R-XTR-6784399 https://reactome.org/PathwayBrowser/#/R-XTR-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Xenopus tropicalis 57945 R-XTR-6797955 https://reactome.org/PathwayBrowser/#/R-XTR-6797955 ALDH7A1 oxidises BETALD to BET IEA Xenopus tropicalis 57945 R-XTR-6801328 https://reactome.org/PathwayBrowser/#/R-XTR-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Xenopus tropicalis 57945 R-XTR-6806831 https://reactome.org/PathwayBrowser/#/R-XTR-6806831 CYB5Rs reduce MetHb to HbA IEA Xenopus tropicalis 57945 R-XTR-6807826 https://reactome.org/PathwayBrowser/#/R-XTR-6807826 LDHAL6B reduces PYR to LACT IEA Xenopus tropicalis 57945 R-XTR-6808464 https://reactome.org/PathwayBrowser/#/R-XTR-6808464 ALDH3B2 oxidises HXAL to PALM IEA Xenopus tropicalis 57945 R-XTR-6809264 https://reactome.org/PathwayBrowser/#/R-XTR-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Xenopus tropicalis 57945 R-XTR-6809287 https://reactome.org/PathwayBrowser/#/R-XTR-6809287 NUDT12 hydrolyses NADH to NMNH IEA Xenopus tropicalis 57945 R-XTR-6813749 https://reactome.org/PathwayBrowser/#/R-XTR-6813749 ALDH1A1 oxidises GA to DGA IEA Xenopus tropicalis 57945 R-XTR-70449 https://reactome.org/PathwayBrowser/#/R-XTR-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Xenopus tropicalis 57945 R-XTR-70482 https://reactome.org/PathwayBrowser/#/R-XTR-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Xenopus tropicalis 57945 R-XTR-70510 https://reactome.org/PathwayBrowser/#/R-XTR-70510 LDH tetramer oxidises LACT to PYR IEA Xenopus tropicalis 57945 R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Xenopus tropicalis 57945 R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Xenopus tropicalis 57945 R-XTR-70664 https://reactome.org/PathwayBrowser/#/R-XTR-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 57945 R-XTR-70679 https://reactome.org/PathwayBrowser/#/R-XTR-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Xenopus tropicalis 57945 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 57945 R-XTR-70837 https://reactome.org/PathwayBrowser/#/R-XTR-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Xenopus tropicalis 57945 R-XTR-70885 https://reactome.org/PathwayBrowser/#/R-XTR-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Xenopus tropicalis 57945 R-XTR-70893 https://reactome.org/PathwayBrowser/#/R-XTR-70893 methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 57945 R-XTR-70940 https://reactome.org/PathwayBrowser/#/R-XTR-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Xenopus tropicalis 57945 R-XTR-70941 https://reactome.org/PathwayBrowser/#/R-XTR-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Xenopus tropicalis 57945 R-XTR-70979 https://reactome.org/PathwayBrowser/#/R-XTR-70979 MDH2 dimer dehydrogenates MAL IEA Xenopus tropicalis 57945 R-XTR-71037 https://reactome.org/PathwayBrowser/#/R-XTR-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 57945 R-XTR-71130 https://reactome.org/PathwayBrowser/#/R-XTR-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Xenopus tropicalis 57945 R-XTR-71260 https://reactome.org/PathwayBrowser/#/R-XTR-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Xenopus tropicalis 57945 R-XTR-71401 https://reactome.org/PathwayBrowser/#/R-XTR-71401 OGDH dimer decarboxylates 2-OG IEA Xenopus tropicalis 57945 R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 57945 R-XTR-71707 https://reactome.org/PathwayBrowser/#/R-XTR-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Xenopus tropicalis 57945 R-XTR-71723 https://reactome.org/PathwayBrowser/#/R-XTR-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Xenopus tropicalis 57945 R-XTR-71849 https://reactome.org/PathwayBrowser/#/R-XTR-71849 LDH tetramer reduces PYR to LACT IEA Xenopus tropicalis 57945 R-XTR-73794 https://reactome.org/PathwayBrowser/#/R-XTR-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Xenopus tropicalis 57945 R-XTR-73912 https://reactome.org/PathwayBrowser/#/R-XTR-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Xenopus tropicalis 57945 R-XTR-73920 https://reactome.org/PathwayBrowser/#/R-XTR-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Xenopus tropicalis 57945 R-XTR-75889 https://reactome.org/PathwayBrowser/#/R-XTR-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Xenopus tropicalis 57945 R-XTR-77254 https://reactome.org/PathwayBrowser/#/R-XTR-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Xenopus tropicalis 57945 R-XTR-77283 https://reactome.org/PathwayBrowser/#/R-XTR-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Xenopus tropicalis 57945 R-XTR-77303 https://reactome.org/PathwayBrowser/#/R-XTR-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Xenopus tropicalis 57945 R-XTR-77312 https://reactome.org/PathwayBrowser/#/R-XTR-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Xenopus tropicalis 57945 R-XTR-77323 https://reactome.org/PathwayBrowser/#/R-XTR-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Xenopus tropicalis 57945 R-XTR-77331 https://reactome.org/PathwayBrowser/#/R-XTR-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Xenopus tropicalis 57945 R-XTR-77342 https://reactome.org/PathwayBrowser/#/R-XTR-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Xenopus tropicalis 57945 R-XTR-888548 https://reactome.org/PathwayBrowser/#/R-XTR-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Xenopus tropicalis 57945 R-XTR-8936442 https://reactome.org/PathwayBrowser/#/R-XTR-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Xenopus tropicalis 57945 R-XTR-9012268 https://reactome.org/PathwayBrowser/#/R-XTR-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 57945 R-XTR-9023968 https://reactome.org/PathwayBrowser/#/R-XTR-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Xenopus tropicalis 57945 R-XTR-9024766 https://reactome.org/PathwayBrowser/#/R-XTR-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Xenopus tropicalis 57945 R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 57945 R-XTR-9727349 https://reactome.org/PathwayBrowser/#/R-XTR-9727349 XDH dehydrogenates xanthine to form urate IEA Xenopus tropicalis 57945 R-XTR-9748945 https://reactome.org/PathwayBrowser/#/R-XTR-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Xenopus tropicalis 57945 R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 57945 R-XTR-9759549 https://reactome.org/PathwayBrowser/#/R-XTR-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Xenopus tropicalis 57945 R-XTR-977348 https://reactome.org/PathwayBrowser/#/R-XTR-977348 PHGDH tetramer dehydrogenates 3PG IEA Xenopus tropicalis 57945 R-XTR-9853499 https://reactome.org/PathwayBrowser/#/R-XTR-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 57945 R-XTR-9856871 https://reactome.org/PathwayBrowser/#/R-XTR-9856871 MDH1 reduces OA IEA Xenopus tropicalis 57945 R-XTR-9861616 https://reactome.org/PathwayBrowser/#/R-XTR-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 57947 R-BTA-200318 https://reactome.org/PathwayBrowser/#/R-BTA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Bos taurus 57947 R-BTA-200326 https://reactome.org/PathwayBrowser/#/R-BTA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Bos taurus 57947 R-BTA-200396 https://reactome.org/PathwayBrowser/#/R-BTA-200396 Creatine transport across the plasma membrane IEA Bos taurus 57947 R-BTA-71286 https://reactome.org/PathwayBrowser/#/R-BTA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Bos taurus 57947 R-CFA-200318 https://reactome.org/PathwayBrowser/#/R-CFA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Canis familiaris 57947 R-CFA-200326 https://reactome.org/PathwayBrowser/#/R-CFA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Canis familiaris 57947 R-CFA-200396 https://reactome.org/PathwayBrowser/#/R-CFA-200396 Creatine transport across the plasma membrane IEA Canis familiaris 57947 R-CFA-71286 https://reactome.org/PathwayBrowser/#/R-CFA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Canis familiaris 57947 R-DRE-200318 https://reactome.org/PathwayBrowser/#/R-DRE-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Danio rerio 57947 R-DRE-200326 https://reactome.org/PathwayBrowser/#/R-DRE-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Danio rerio 57947 R-DRE-71286 https://reactome.org/PathwayBrowser/#/R-DRE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Danio rerio 57947 R-GGA-200318 https://reactome.org/PathwayBrowser/#/R-GGA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Gallus gallus 57947 R-GGA-200326 https://reactome.org/PathwayBrowser/#/R-GGA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Gallus gallus 57947 R-GGA-71286 https://reactome.org/PathwayBrowser/#/R-GGA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Gallus gallus 57947 R-HSA-200318 https://reactome.org/PathwayBrowser/#/R-HSA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] TAS Homo sapiens 57947 R-HSA-200326 https://reactome.org/PathwayBrowser/#/R-HSA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] TAS Homo sapiens 57947 R-HSA-200396 https://reactome.org/PathwayBrowser/#/R-HSA-200396 Creatine transport across the plasma membrane TAS Homo sapiens 57947 R-HSA-71286 https://reactome.org/PathwayBrowser/#/R-HSA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine TAS Homo sapiens 57947 R-MMU-200318 https://reactome.org/PathwayBrowser/#/R-MMU-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Mus musculus 57947 R-MMU-200326 https://reactome.org/PathwayBrowser/#/R-MMU-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Mus musculus 57947 R-MMU-200396 https://reactome.org/PathwayBrowser/#/R-MMU-200396 Creatine transport across the plasma membrane IEA Mus musculus 57947 R-MMU-71286 https://reactome.org/PathwayBrowser/#/R-MMU-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Mus musculus 57947 R-PFA-200396 https://reactome.org/PathwayBrowser/#/R-PFA-200396 Creatine transport across the plasma membrane IEA Plasmodium falciparum 57947 R-RNO-200318 https://reactome.org/PathwayBrowser/#/R-RNO-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Rattus norvegicus 57947 R-RNO-200326 https://reactome.org/PathwayBrowser/#/R-RNO-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Rattus norvegicus 57947 R-RNO-200396 https://reactome.org/PathwayBrowser/#/R-RNO-200396 Creatine transport across the plasma membrane IEA Rattus norvegicus 57947 R-RNO-71286 https://reactome.org/PathwayBrowser/#/R-RNO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Rattus norvegicus 57947 R-SCE-71286 https://reactome.org/PathwayBrowser/#/R-SCE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Saccharomyces cerevisiae 57947 R-SPO-71286 https://reactome.org/PathwayBrowser/#/R-SPO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Schizosaccharomyces pombe 57947 R-SSC-200318 https://reactome.org/PathwayBrowser/#/R-SSC-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Sus scrofa 57947 R-SSC-200326 https://reactome.org/PathwayBrowser/#/R-SSC-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Sus scrofa 57947 R-SSC-200396 https://reactome.org/PathwayBrowser/#/R-SSC-200396 Creatine transport across the plasma membrane IEA Sus scrofa 57947 R-SSC-71286 https://reactome.org/PathwayBrowser/#/R-SSC-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Sus scrofa 57947 R-XTR-200318 https://reactome.org/PathwayBrowser/#/R-XTR-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Xenopus tropicalis 57947 R-XTR-200326 https://reactome.org/PathwayBrowser/#/R-XTR-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Xenopus tropicalis 57947 R-XTR-200396 https://reactome.org/PathwayBrowser/#/R-XTR-200396 Creatine transport across the plasma membrane IEA Xenopus tropicalis 57947 R-XTR-71286 https://reactome.org/PathwayBrowser/#/R-XTR-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Xenopus tropicalis 57966 R-BTA-351987 https://reactome.org/PathwayBrowser/#/R-BTA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Bos taurus 57966 R-BTA-352029 https://reactome.org/PathwayBrowser/#/R-BTA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Bos taurus 57966 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 57966 R-BTA-6786245 https://reactome.org/PathwayBrowser/#/R-BTA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Bos taurus 57966 R-BTA-6787757 https://reactome.org/PathwayBrowser/#/R-BTA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Bos taurus 57966 R-BTA-73591 https://reactome.org/PathwayBrowser/#/R-BTA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Bos taurus 57966 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 57966 R-CEL-73591 https://reactome.org/PathwayBrowser/#/R-CEL-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Caenorhabditis elegans 57966 R-CFA-351987 https://reactome.org/PathwayBrowser/#/R-CFA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Canis familiaris 57966 R-CFA-352029 https://reactome.org/PathwayBrowser/#/R-CFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Canis familiaris 57966 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 57966 R-CFA-6786245 https://reactome.org/PathwayBrowser/#/R-CFA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Canis familiaris 57966 R-CFA-6787757 https://reactome.org/PathwayBrowser/#/R-CFA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Canis familiaris 57966 R-CFA-73591 https://reactome.org/PathwayBrowser/#/R-CFA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Canis familiaris 57966 R-DDI-73591 https://reactome.org/PathwayBrowser/#/R-DDI-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Dictyostelium discoideum 57966 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57966 R-DME-6787757 https://reactome.org/PathwayBrowser/#/R-DME-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Drosophila melanogaster 57966 R-DME-73591 https://reactome.org/PathwayBrowser/#/R-DME-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Drosophila melanogaster 57966 R-DRE-351987 https://reactome.org/PathwayBrowser/#/R-DRE-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Danio rerio 57966 R-DRE-352029 https://reactome.org/PathwayBrowser/#/R-DRE-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Danio rerio 57966 R-DRE-73591 https://reactome.org/PathwayBrowser/#/R-DRE-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Danio rerio 57966 R-GGA-351987 https://reactome.org/PathwayBrowser/#/R-GGA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Gallus gallus 57966 R-GGA-352029 https://reactome.org/PathwayBrowser/#/R-GGA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Gallus gallus 57966 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 57966 R-GGA-6786245 https://reactome.org/PathwayBrowser/#/R-GGA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Gallus gallus 57966 R-GGA-6787757 https://reactome.org/PathwayBrowser/#/R-GGA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Gallus gallus 57966 R-GGA-73591 https://reactome.org/PathwayBrowser/#/R-GGA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Gallus gallus 57966 R-HSA-351987 https://reactome.org/PathwayBrowser/#/R-HSA-351987 SLC6A6-mediated uptake of taurine and beta-alanine TAS Homo sapiens 57966 R-HSA-352029 https://reactome.org/PathwayBrowser/#/R-HSA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine TAS Homo sapiens 57966 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57966 R-HSA-6786245 https://reactome.org/PathwayBrowser/#/R-HSA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN TAS Homo sapiens 57966 R-HSA-6787757 https://reactome.org/PathwayBrowser/#/R-HSA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs TAS Homo sapiens 57966 R-HSA-73591 https://reactome.org/PathwayBrowser/#/R-HSA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 TAS Homo sapiens 57966 R-HSA-909765 https://reactome.org/PathwayBrowser/#/R-HSA-909765 Mitochondrial uptake of beta-alanine IEA Homo sapiens 57966 R-HSA-909776 https://reactome.org/PathwayBrowser/#/R-HSA-909776 beta-alanine + pyruvate => 3-oxopropanoate + alanine IEA Homo sapiens 57966 R-MMU-351987 https://reactome.org/PathwayBrowser/#/R-MMU-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Mus musculus 57966 R-MMU-352029 https://reactome.org/PathwayBrowser/#/R-MMU-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Mus musculus 57966 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 57966 R-MMU-6786245 https://reactome.org/PathwayBrowser/#/R-MMU-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Mus musculus 57966 R-MMU-6787757 https://reactome.org/PathwayBrowser/#/R-MMU-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Mus musculus 57966 R-MMU-73591 https://reactome.org/PathwayBrowser/#/R-MMU-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Mus musculus 57966 R-PFA-351987 https://reactome.org/PathwayBrowser/#/R-PFA-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Plasmodium falciparum 57966 R-PFA-352029 https://reactome.org/PathwayBrowser/#/R-PFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Plasmodium falciparum 57966 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57966 R-RNO-351987 https://reactome.org/PathwayBrowser/#/R-RNO-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Rattus norvegicus 57966 R-RNO-352029 https://reactome.org/PathwayBrowser/#/R-RNO-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Rattus norvegicus 57966 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 57966 R-RNO-6786245 https://reactome.org/PathwayBrowser/#/R-RNO-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Rattus norvegicus 57966 R-RNO-6787757 https://reactome.org/PathwayBrowser/#/R-RNO-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Rattus norvegicus 57966 R-RNO-73591 https://reactome.org/PathwayBrowser/#/R-RNO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Rattus norvegicus 57966 R-RNO-909762 https://reactome.org/PathwayBrowser/#/R-RNO-909762 beta-alanine + pyruvate => 3-oxopropanoate + alanine TAS Rattus norvegicus 57966 R-RNO-909763 https://reactome.org/PathwayBrowser/#/R-RNO-909763 Mitochondrial uptake of beta-alanine TAS Rattus norvegicus 57966 R-SPO-73591 https://reactome.org/PathwayBrowser/#/R-SPO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Schizosaccharomyces pombe 57966 R-SSC-351987 https://reactome.org/PathwayBrowser/#/R-SSC-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Sus scrofa 57966 R-SSC-352029 https://reactome.org/PathwayBrowser/#/R-SSC-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Sus scrofa 57966 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 57966 R-SSC-6786245 https://reactome.org/PathwayBrowser/#/R-SSC-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Sus scrofa 57966 R-SSC-6787757 https://reactome.org/PathwayBrowser/#/R-SSC-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Sus scrofa 57966 R-SSC-73591 https://reactome.org/PathwayBrowser/#/R-SSC-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Sus scrofa 57966 R-XTR-351987 https://reactome.org/PathwayBrowser/#/R-XTR-351987 SLC6A6-mediated uptake of taurine and beta-alanine IEA Xenopus tropicalis 57966 R-XTR-352029 https://reactome.org/PathwayBrowser/#/R-XTR-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Xenopus tropicalis 57966 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57966 R-XTR-6786245 https://reactome.org/PathwayBrowser/#/R-XTR-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Xenopus tropicalis 57966 R-XTR-6787757 https://reactome.org/PathwayBrowser/#/R-XTR-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Xenopus tropicalis 57967 R-BTA-2393939 https://reactome.org/PathwayBrowser/#/R-BTA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 57967 R-BTA-2393954 https://reactome.org/PathwayBrowser/#/R-BTA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 57967 R-BTA-5696049 https://reactome.org/PathwayBrowser/#/R-BTA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 57967 R-BTA-8870346 https://reactome.org/PathwayBrowser/#/R-BTA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Bos taurus 57967 R-BTA-8938076 https://reactome.org/PathwayBrowser/#/R-BTA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Bos taurus 57967 R-BTA-8952903 https://reactome.org/PathwayBrowser/#/R-BTA-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Bos taurus 57967 R-CEL-2393939 https://reactome.org/PathwayBrowser/#/R-CEL-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 57967 R-CEL-2393954 https://reactome.org/PathwayBrowser/#/R-CEL-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 57967 R-CFA-2393939 https://reactome.org/PathwayBrowser/#/R-CFA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 57967 R-CFA-2393954 https://reactome.org/PathwayBrowser/#/R-CFA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 57967 R-CFA-5696049 https://reactome.org/PathwayBrowser/#/R-CFA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 57967 R-CFA-8870346 https://reactome.org/PathwayBrowser/#/R-CFA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Canis familiaris 57967 R-CFA-8938076 https://reactome.org/PathwayBrowser/#/R-CFA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Canis familiaris 57967 R-DDI-2393939 https://reactome.org/PathwayBrowser/#/R-DDI-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Dictyostelium discoideum 57967 R-DME-2393954 https://reactome.org/PathwayBrowser/#/R-DME-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Drosophila melanogaster 57967 R-DRE-2393939 https://reactome.org/PathwayBrowser/#/R-DRE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 57967 R-DRE-5696049 https://reactome.org/PathwayBrowser/#/R-DRE-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 57967 R-DRE-8952903 https://reactome.org/PathwayBrowser/#/R-DRE-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Danio rerio 57967 R-GGA-2393939 https://reactome.org/PathwayBrowser/#/R-GGA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 57967 R-GGA-2393954 https://reactome.org/PathwayBrowser/#/R-GGA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 57967 R-GGA-5696049 https://reactome.org/PathwayBrowser/#/R-GGA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 57967 R-GGA-8870346 https://reactome.org/PathwayBrowser/#/R-GGA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Gallus gallus 57967 R-GGA-8938076 https://reactome.org/PathwayBrowser/#/R-GGA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Gallus gallus 57967 R-GGA-8952903 https://reactome.org/PathwayBrowser/#/R-GGA-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Gallus gallus 57967 R-HSA-2393939 https://reactome.org/PathwayBrowser/#/R-HSA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 57967 R-HSA-2393954 https://reactome.org/PathwayBrowser/#/R-HSA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 57967 R-HSA-5696049 https://reactome.org/PathwayBrowser/#/R-HSA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 57967 R-HSA-8870346 https://reactome.org/PathwayBrowser/#/R-HSA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose TAS Homo sapiens 57967 R-HSA-8938076 https://reactome.org/PathwayBrowser/#/R-HSA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose TAS Homo sapiens 57967 R-HSA-8952903 https://reactome.org/PathwayBrowser/#/R-HSA-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) TAS Homo sapiens 57967 R-HSA-9637699 https://reactome.org/PathwayBrowser/#/R-HSA-9637699 CpnT hydrolyses NAD+ TAS Homo sapiens 57967 R-MMU-2393939 https://reactome.org/PathwayBrowser/#/R-MMU-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 57967 R-MMU-2393954 https://reactome.org/PathwayBrowser/#/R-MMU-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 57967 R-MMU-5696049 https://reactome.org/PathwayBrowser/#/R-MMU-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 57967 R-MMU-8870346 https://reactome.org/PathwayBrowser/#/R-MMU-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Mus musculus 57967 R-MMU-8938076 https://reactome.org/PathwayBrowser/#/R-MMU-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Mus musculus 57967 R-MMU-8952903 https://reactome.org/PathwayBrowser/#/R-MMU-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Mus musculus 57967 R-RNO-2393939 https://reactome.org/PathwayBrowser/#/R-RNO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 57967 R-RNO-2393954 https://reactome.org/PathwayBrowser/#/R-RNO-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 57967 R-RNO-5696049 https://reactome.org/PathwayBrowser/#/R-RNO-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 57967 R-RNO-8870346 https://reactome.org/PathwayBrowser/#/R-RNO-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Rattus norvegicus 57967 R-RNO-8938076 https://reactome.org/PathwayBrowser/#/R-RNO-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Rattus norvegicus 57967 R-RNO-8952903 https://reactome.org/PathwayBrowser/#/R-RNO-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Rattus norvegicus 57967 R-SCE-2393939 https://reactome.org/PathwayBrowser/#/R-SCE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Saccharomyces cerevisiae 57967 R-SPO-2393939 https://reactome.org/PathwayBrowser/#/R-SPO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Schizosaccharomyces pombe 57967 R-SSC-2393939 https://reactome.org/PathwayBrowser/#/R-SSC-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 57967 R-SSC-2393954 https://reactome.org/PathwayBrowser/#/R-SSC-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 57967 R-SSC-5696049 https://reactome.org/PathwayBrowser/#/R-SSC-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 57967 R-SSC-8870346 https://reactome.org/PathwayBrowser/#/R-SSC-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Sus scrofa 57967 R-SSC-8938076 https://reactome.org/PathwayBrowser/#/R-SSC-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Sus scrofa 57967 R-SSC-8952903 https://reactome.org/PathwayBrowser/#/R-SSC-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Sus scrofa 57967 R-XTR-2393939 https://reactome.org/PathwayBrowser/#/R-XTR-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 57967 R-XTR-2393954 https://reactome.org/PathwayBrowser/#/R-XTR-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 57967 R-XTR-5696049 https://reactome.org/PathwayBrowser/#/R-XTR-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 57967 R-XTR-8870346 https://reactome.org/PathwayBrowser/#/R-XTR-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Xenopus tropicalis 57967 R-XTR-8938076 https://reactome.org/PathwayBrowser/#/R-XTR-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Xenopus tropicalis 57967 R-XTR-8952903 https://reactome.org/PathwayBrowser/#/R-XTR-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Xenopus tropicalis 57972 R-BTA-1362408 https://reactome.org/PathwayBrowser/#/R-BTA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Bos taurus 57972 R-BTA-209840 https://reactome.org/PathwayBrowser/#/R-BTA-209840 Two DITs combine to form thyroxine IEA Bos taurus 57972 R-BTA-209925 https://reactome.org/PathwayBrowser/#/R-BTA-209925 DIT and MIT combine to form triiodothyronine IEA Bos taurus 57972 R-BTA-2408524 https://reactome.org/PathwayBrowser/#/R-BTA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Bos taurus 57972 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 57972 R-BTA-352108 https://reactome.org/PathwayBrowser/#/R-BTA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Bos taurus 57972 R-BTA-352119 https://reactome.org/PathwayBrowser/#/R-BTA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Bos taurus 57972 R-BTA-352174 https://reactome.org/PathwayBrowser/#/R-BTA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Bos taurus 57972 R-BTA-352182 https://reactome.org/PathwayBrowser/#/R-BTA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Bos taurus 57972 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 57972 R-BTA-352347 https://reactome.org/PathwayBrowser/#/R-BTA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Bos taurus 57972 R-BTA-352354 https://reactome.org/PathwayBrowser/#/R-BTA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Bos taurus 57972 R-BTA-352364 https://reactome.org/PathwayBrowser/#/R-BTA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Bos taurus 57972 R-BTA-352371 https://reactome.org/PathwayBrowser/#/R-BTA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Bos taurus 57972 R-BTA-352379 https://reactome.org/PathwayBrowser/#/R-BTA-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Bos taurus 57972 R-BTA-352385 https://reactome.org/PathwayBrowser/#/R-BTA-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Bos taurus 57972 R-BTA-375417 https://reactome.org/PathwayBrowser/#/R-BTA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Bos taurus 57972 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 57972 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 57972 R-BTA-376200 https://reactome.org/PathwayBrowser/#/R-BTA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Bos taurus 57972 R-BTA-389684 https://reactome.org/PathwayBrowser/#/R-BTA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Bos taurus 57972 R-BTA-507749 https://reactome.org/PathwayBrowser/#/R-BTA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Bos taurus 57972 R-BTA-507775 https://reactome.org/PathwayBrowser/#/R-BTA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Bos taurus 57972 R-BTA-70523 https://reactome.org/PathwayBrowser/#/R-BTA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Bos taurus 57972 R-BTA-70524 https://reactome.org/PathwayBrowser/#/R-BTA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Bos taurus 57972 R-BTA-71217 https://reactome.org/PathwayBrowser/#/R-BTA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Bos taurus 57972 R-BTA-893593 https://reactome.org/PathwayBrowser/#/R-BTA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Bos taurus 57972 R-BTA-893596 https://reactome.org/PathwayBrowser/#/R-BTA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Bos taurus 57972 R-BTA-893616 https://reactome.org/PathwayBrowser/#/R-BTA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Bos taurus 57972 R-BTA-904864 https://reactome.org/PathwayBrowser/#/R-BTA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Bos taurus 57972 R-BTA-947499 https://reactome.org/PathwayBrowser/#/R-BTA-947499 Exchange of oxygen with sulfur in MoCo IEA Bos taurus 57972 R-BTA-947514 https://reactome.org/PathwayBrowser/#/R-BTA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Bos taurus 57972 R-CEL-1362408 https://reactome.org/PathwayBrowser/#/R-CEL-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Caenorhabditis elegans 57972 R-CEL-209840 https://reactome.org/PathwayBrowser/#/R-CEL-209840 Two DITs combine to form thyroxine IEA Caenorhabditis elegans 57972 R-CEL-209925 https://reactome.org/PathwayBrowser/#/R-CEL-209925 DIT and MIT combine to form triiodothyronine IEA Caenorhabditis elegans 57972 R-CEL-2408524 https://reactome.org/PathwayBrowser/#/R-CEL-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Caenorhabditis elegans 57972 R-CEL-352347 https://reactome.org/PathwayBrowser/#/R-CEL-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Caenorhabditis elegans 57972 R-CEL-352354 https://reactome.org/PathwayBrowser/#/R-CEL-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Caenorhabditis elegans 57972 R-CEL-352364 https://reactome.org/PathwayBrowser/#/R-CEL-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Caenorhabditis elegans 57972 R-CEL-352371 https://reactome.org/PathwayBrowser/#/R-CEL-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Caenorhabditis elegans 57972 R-CEL-352379 https://reactome.org/PathwayBrowser/#/R-CEL-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Caenorhabditis elegans 57972 R-CEL-352385 https://reactome.org/PathwayBrowser/#/R-CEL-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Caenorhabditis elegans 57972 R-CEL-375417 https://reactome.org/PathwayBrowser/#/R-CEL-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Caenorhabditis elegans 57972 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 57972 R-CEL-389684 https://reactome.org/PathwayBrowser/#/R-CEL-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Caenorhabditis elegans 57972 R-CEL-507749 https://reactome.org/PathwayBrowser/#/R-CEL-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Caenorhabditis elegans 57972 R-CEL-507775 https://reactome.org/PathwayBrowser/#/R-CEL-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Caenorhabditis elegans 57972 R-CEL-70523 https://reactome.org/PathwayBrowser/#/R-CEL-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Caenorhabditis elegans 57972 R-CEL-70524 https://reactome.org/PathwayBrowser/#/R-CEL-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Caenorhabditis elegans 57972 R-CEL-71217 https://reactome.org/PathwayBrowser/#/R-CEL-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Caenorhabditis elegans 57972 R-CEL-893593 https://reactome.org/PathwayBrowser/#/R-CEL-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Caenorhabditis elegans 57972 R-CEL-893596 https://reactome.org/PathwayBrowser/#/R-CEL-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Caenorhabditis elegans 57972 R-CEL-893616 https://reactome.org/PathwayBrowser/#/R-CEL-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Caenorhabditis elegans 57972 R-CEL-904864 https://reactome.org/PathwayBrowser/#/R-CEL-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Caenorhabditis elegans 57972 R-CEL-947499 https://reactome.org/PathwayBrowser/#/R-CEL-947499 Exchange of oxygen with sulfur in MoCo IEA Caenorhabditis elegans 57972 R-CEL-947514 https://reactome.org/PathwayBrowser/#/R-CEL-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Caenorhabditis elegans 57972 R-CFA-1362408 https://reactome.org/PathwayBrowser/#/R-CFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Canis familiaris 57972 R-CFA-209840 https://reactome.org/PathwayBrowser/#/R-CFA-209840 Two DITs combine to form thyroxine IEA Canis familiaris 57972 R-CFA-209925 https://reactome.org/PathwayBrowser/#/R-CFA-209925 DIT and MIT combine to form triiodothyronine IEA Canis familiaris 57972 R-CFA-2408524 https://reactome.org/PathwayBrowser/#/R-CFA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Canis familiaris 57972 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 57972 R-CFA-352108 https://reactome.org/PathwayBrowser/#/R-CFA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Canis familiaris 57972 R-CFA-352119 https://reactome.org/PathwayBrowser/#/R-CFA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Canis familiaris 57972 R-CFA-352174 https://reactome.org/PathwayBrowser/#/R-CFA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Canis familiaris 57972 R-CFA-352182 https://reactome.org/PathwayBrowser/#/R-CFA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Canis familiaris 57972 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 57972 R-CFA-352347 https://reactome.org/PathwayBrowser/#/R-CFA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Canis familiaris 57972 R-CFA-352354 https://reactome.org/PathwayBrowser/#/R-CFA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Canis familiaris 57972 R-CFA-352364 https://reactome.org/PathwayBrowser/#/R-CFA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Canis familiaris 57972 R-CFA-352371 https://reactome.org/PathwayBrowser/#/R-CFA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Canis familiaris 57972 R-CFA-352379 https://reactome.org/PathwayBrowser/#/R-CFA-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Canis familiaris 57972 R-CFA-352385 https://reactome.org/PathwayBrowser/#/R-CFA-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Canis familiaris 57972 R-CFA-375417 https://reactome.org/PathwayBrowser/#/R-CFA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Canis familiaris 57972 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 57972 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 57972 R-CFA-376200 https://reactome.org/PathwayBrowser/#/R-CFA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Canis familiaris 57972 R-CFA-389684 https://reactome.org/PathwayBrowser/#/R-CFA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Canis familiaris 57972 R-CFA-507749 https://reactome.org/PathwayBrowser/#/R-CFA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Canis familiaris 57972 R-CFA-507775 https://reactome.org/PathwayBrowser/#/R-CFA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Canis familiaris 57972 R-CFA-70523 https://reactome.org/PathwayBrowser/#/R-CFA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Canis familiaris 57972 R-CFA-70524 https://reactome.org/PathwayBrowser/#/R-CFA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Canis familiaris 57972 R-CFA-71217 https://reactome.org/PathwayBrowser/#/R-CFA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Canis familiaris 57972 R-CFA-893593 https://reactome.org/PathwayBrowser/#/R-CFA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Canis familiaris 57972 R-CFA-893596 https://reactome.org/PathwayBrowser/#/R-CFA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Canis familiaris 57972 R-CFA-893616 https://reactome.org/PathwayBrowser/#/R-CFA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Canis familiaris 57972 R-CFA-904864 https://reactome.org/PathwayBrowser/#/R-CFA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Canis familiaris 57972 R-CFA-947499 https://reactome.org/PathwayBrowser/#/R-CFA-947499 Exchange of oxygen with sulfur in MoCo IEA Canis familiaris 57972 R-CFA-947514 https://reactome.org/PathwayBrowser/#/R-CFA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Canis familiaris 57972 R-DDI-1362408 https://reactome.org/PathwayBrowser/#/R-DDI-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Dictyostelium discoideum 57972 R-DDI-209840 https://reactome.org/PathwayBrowser/#/R-DDI-209840 Two DITs combine to form thyroxine IEA Dictyostelium discoideum 57972 R-DDI-209925 https://reactome.org/PathwayBrowser/#/R-DDI-209925 DIT and MIT combine to form triiodothyronine IEA Dictyostelium discoideum 57972 R-DDI-375417 https://reactome.org/PathwayBrowser/#/R-DDI-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Dictyostelium discoideum 57972 R-DDI-389684 https://reactome.org/PathwayBrowser/#/R-DDI-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Dictyostelium discoideum 57972 R-DDI-507749 https://reactome.org/PathwayBrowser/#/R-DDI-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Dictyostelium discoideum 57972 R-DDI-507775 https://reactome.org/PathwayBrowser/#/R-DDI-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Dictyostelium discoideum 57972 R-DDI-70523 https://reactome.org/PathwayBrowser/#/R-DDI-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Dictyostelium discoideum 57972 R-DDI-70524 https://reactome.org/PathwayBrowser/#/R-DDI-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Dictyostelium discoideum 57972 R-DDI-71217 https://reactome.org/PathwayBrowser/#/R-DDI-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Dictyostelium discoideum 57972 R-DDI-893593 https://reactome.org/PathwayBrowser/#/R-DDI-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Dictyostelium discoideum 57972 R-DDI-893596 https://reactome.org/PathwayBrowser/#/R-DDI-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Dictyostelium discoideum 57972 R-DDI-893616 https://reactome.org/PathwayBrowser/#/R-DDI-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Dictyostelium discoideum 57972 R-DDI-947499 https://reactome.org/PathwayBrowser/#/R-DDI-947499 Exchange of oxygen with sulfur in MoCo IEA Dictyostelium discoideum 57972 R-DDI-947514 https://reactome.org/PathwayBrowser/#/R-DDI-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Dictyostelium discoideum 57972 R-DME-1362408 https://reactome.org/PathwayBrowser/#/R-DME-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Drosophila melanogaster 57972 R-DME-209840 https://reactome.org/PathwayBrowser/#/R-DME-209840 Two DITs combine to form thyroxine IEA Drosophila melanogaster 57972 R-DME-209925 https://reactome.org/PathwayBrowser/#/R-DME-209925 DIT and MIT combine to form triiodothyronine IEA Drosophila melanogaster 57972 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 57972 R-DME-352108 https://reactome.org/PathwayBrowser/#/R-DME-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57972 R-DME-352119 https://reactome.org/PathwayBrowser/#/R-DME-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57972 R-DME-352174 https://reactome.org/PathwayBrowser/#/R-DME-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Drosophila melanogaster 57972 R-DME-352182 https://reactome.org/PathwayBrowser/#/R-DME-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Drosophila melanogaster 57972 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 57972 R-DME-352347 https://reactome.org/PathwayBrowser/#/R-DME-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Drosophila melanogaster 57972 R-DME-352354 https://reactome.org/PathwayBrowser/#/R-DME-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Drosophila melanogaster 57972 R-DME-352364 https://reactome.org/PathwayBrowser/#/R-DME-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Drosophila melanogaster 57972 R-DME-352371 https://reactome.org/PathwayBrowser/#/R-DME-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Drosophila melanogaster 57972 R-DME-352379 https://reactome.org/PathwayBrowser/#/R-DME-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Drosophila melanogaster 57972 R-DME-352385 https://reactome.org/PathwayBrowser/#/R-DME-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Drosophila melanogaster 57972 R-DME-375417 https://reactome.org/PathwayBrowser/#/R-DME-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Drosophila melanogaster 57972 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57972 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 57972 R-DME-376200 https://reactome.org/PathwayBrowser/#/R-DME-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Drosophila melanogaster 57972 R-DME-389684 https://reactome.org/PathwayBrowser/#/R-DME-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Drosophila melanogaster 57972 R-DME-507749 https://reactome.org/PathwayBrowser/#/R-DME-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Drosophila melanogaster 57972 R-DME-507775 https://reactome.org/PathwayBrowser/#/R-DME-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Drosophila melanogaster 57972 R-DME-70523 https://reactome.org/PathwayBrowser/#/R-DME-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Drosophila melanogaster 57972 R-DME-70524 https://reactome.org/PathwayBrowser/#/R-DME-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Drosophila melanogaster 57972 R-DME-893593 https://reactome.org/PathwayBrowser/#/R-DME-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Drosophila melanogaster 57972 R-DME-893596 https://reactome.org/PathwayBrowser/#/R-DME-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Drosophila melanogaster 57972 R-DME-893616 https://reactome.org/PathwayBrowser/#/R-DME-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Drosophila melanogaster 57972 R-DME-904864 https://reactome.org/PathwayBrowser/#/R-DME-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Drosophila melanogaster 57972 R-DME-947499 https://reactome.org/PathwayBrowser/#/R-DME-947499 Exchange of oxygen with sulfur in MoCo IEA Drosophila melanogaster 57972 R-DME-947514 https://reactome.org/PathwayBrowser/#/R-DME-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Drosophila melanogaster 57972 R-DRE-1362408 https://reactome.org/PathwayBrowser/#/R-DRE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Danio rerio 57972 R-DRE-2408524 https://reactome.org/PathwayBrowser/#/R-DRE-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Danio rerio 57972 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 57972 R-DRE-352108 https://reactome.org/PathwayBrowser/#/R-DRE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Danio rerio 57972 R-DRE-352182 https://reactome.org/PathwayBrowser/#/R-DRE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Danio rerio 57972 R-DRE-352347 https://reactome.org/PathwayBrowser/#/R-DRE-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Danio rerio 57972 R-DRE-352354 https://reactome.org/PathwayBrowser/#/R-DRE-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Danio rerio 57972 R-DRE-352364 https://reactome.org/PathwayBrowser/#/R-DRE-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Danio rerio 57972 R-DRE-352371 https://reactome.org/PathwayBrowser/#/R-DRE-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Danio rerio 57972 R-DRE-352379 https://reactome.org/PathwayBrowser/#/R-DRE-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Danio rerio 57972 R-DRE-352385 https://reactome.org/PathwayBrowser/#/R-DRE-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Danio rerio 57972 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 57972 R-DRE-389684 https://reactome.org/PathwayBrowser/#/R-DRE-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Danio rerio 57972 R-DRE-70523 https://reactome.org/PathwayBrowser/#/R-DRE-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Danio rerio 57972 R-DRE-70524 https://reactome.org/PathwayBrowser/#/R-DRE-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Danio rerio 57972 R-DRE-893593 https://reactome.org/PathwayBrowser/#/R-DRE-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Danio rerio 57972 R-DRE-893596 https://reactome.org/PathwayBrowser/#/R-DRE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Danio rerio 57972 R-DRE-893616 https://reactome.org/PathwayBrowser/#/R-DRE-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Danio rerio 57972 R-DRE-904864 https://reactome.org/PathwayBrowser/#/R-DRE-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Danio rerio 57972 R-DRE-947499 https://reactome.org/PathwayBrowser/#/R-DRE-947499 Exchange of oxygen with sulfur in MoCo IEA Danio rerio 57972 R-DRE-947514 https://reactome.org/PathwayBrowser/#/R-DRE-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Danio rerio 57972 R-GGA-1362408 https://reactome.org/PathwayBrowser/#/R-GGA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Gallus gallus 57972 R-GGA-209840 https://reactome.org/PathwayBrowser/#/R-GGA-209840 Two DITs combine to form thyroxine IEA Gallus gallus 57972 R-GGA-209925 https://reactome.org/PathwayBrowser/#/R-GGA-209925 DIT and MIT combine to form triiodothyronine IEA Gallus gallus 57972 R-GGA-2408524 https://reactome.org/PathwayBrowser/#/R-GGA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Gallus gallus 57972 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 57972 R-GGA-352108 https://reactome.org/PathwayBrowser/#/R-GGA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Gallus gallus 57972 R-GGA-352119 https://reactome.org/PathwayBrowser/#/R-GGA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Gallus gallus 57972 R-GGA-352174 https://reactome.org/PathwayBrowser/#/R-GGA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Gallus gallus 57972 R-GGA-352347 https://reactome.org/PathwayBrowser/#/R-GGA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Gallus gallus 57972 R-GGA-352354 https://reactome.org/PathwayBrowser/#/R-GGA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Gallus gallus 57972 R-GGA-352364 https://reactome.org/PathwayBrowser/#/R-GGA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Gallus gallus 57972 R-GGA-352371 https://reactome.org/PathwayBrowser/#/R-GGA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Gallus gallus 57972 R-GGA-375417 https://reactome.org/PathwayBrowser/#/R-GGA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Gallus gallus 57972 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 57972 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 57972 R-GGA-389684 https://reactome.org/PathwayBrowser/#/R-GGA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Gallus gallus 57972 R-GGA-507749 https://reactome.org/PathwayBrowser/#/R-GGA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Gallus gallus 57972 R-GGA-507775 https://reactome.org/PathwayBrowser/#/R-GGA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Gallus gallus 57972 R-GGA-71217 https://reactome.org/PathwayBrowser/#/R-GGA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Gallus gallus 57972 R-GGA-893593 https://reactome.org/PathwayBrowser/#/R-GGA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Gallus gallus 57972 R-GGA-893596 https://reactome.org/PathwayBrowser/#/R-GGA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Gallus gallus 57972 R-GGA-893616 https://reactome.org/PathwayBrowser/#/R-GGA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Gallus gallus 57972 R-GGA-904864 https://reactome.org/PathwayBrowser/#/R-GGA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Gallus gallus 57972 R-GGA-947499 https://reactome.org/PathwayBrowser/#/R-GGA-947499 Exchange of oxygen with sulfur in MoCo IEA Gallus gallus 57972 R-GGA-947514 https://reactome.org/PathwayBrowser/#/R-GGA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Gallus gallus 57972 R-HSA-1362408 https://reactome.org/PathwayBrowser/#/R-HSA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster TAS Homo sapiens 57972 R-HSA-209840 https://reactome.org/PathwayBrowser/#/R-HSA-209840 Two DITs combine to form thyroxine TAS Homo sapiens 57972 R-HSA-209925 https://reactome.org/PathwayBrowser/#/R-HSA-209925 DIT and MIT combine to form triiodothyronine TAS Homo sapiens 57972 R-HSA-2408524 https://reactome.org/PathwayBrowser/#/R-HSA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer TAS Homo sapiens 57972 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 57972 R-HSA-352108 https://reactome.org/PathwayBrowser/#/R-HSA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids TAS Homo sapiens 57972 R-HSA-352119 https://reactome.org/PathwayBrowser/#/R-HSA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids TAS Homo sapiens 57972 R-HSA-352174 https://reactome.org/PathwayBrowser/#/R-HSA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine TAS Homo sapiens 57972 R-HSA-352182 https://reactome.org/PathwayBrowser/#/R-HSA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine TAS Homo sapiens 57972 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 57972 R-HSA-352347 https://reactome.org/PathwayBrowser/#/R-HSA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine TAS Homo sapiens 57972 R-HSA-352354 https://reactome.org/PathwayBrowser/#/R-HSA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine TAS Homo sapiens 57972 R-HSA-352364 https://reactome.org/PathwayBrowser/#/R-HSA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine TAS Homo sapiens 57972 R-HSA-352371 https://reactome.org/PathwayBrowser/#/R-HSA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine TAS Homo sapiens 57972 R-HSA-352379 https://reactome.org/PathwayBrowser/#/R-HSA-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane TAS Homo sapiens 57972 R-HSA-352385 https://reactome.org/PathwayBrowser/#/R-HSA-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane TAS Homo sapiens 57972 R-HSA-375417 https://reactome.org/PathwayBrowser/#/R-HSA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine TAS Homo sapiens 57972 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57972 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57972 R-HSA-376200 https://reactome.org/PathwayBrowser/#/R-HSA-376200 SLC7A10-mediated uptake of small neutral amino acids TAS Homo sapiens 57972 R-HSA-379864 https://reactome.org/PathwayBrowser/#/R-HSA-379864 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate TAS Homo sapiens 57972 R-HSA-380177 https://reactome.org/PathwayBrowser/#/R-HSA-380177 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate IEA Homo sapiens 57972 R-HSA-389684 https://reactome.org/PathwayBrowser/#/R-HSA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] TAS Homo sapiens 57972 R-HSA-507749 https://reactome.org/PathwayBrowser/#/R-HSA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala TAS Homo sapiens 57972 R-HSA-507775 https://reactome.org/PathwayBrowser/#/R-HSA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR TAS Homo sapiens 57972 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 57972 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 57972 R-HSA-70523 https://reactome.org/PathwayBrowser/#/R-HSA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR TAS Homo sapiens 57972 R-HSA-70524 https://reactome.org/PathwayBrowser/#/R-HSA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala TAS Homo sapiens 57972 R-HSA-71217 https://reactome.org/PathwayBrowser/#/R-HSA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine TAS Homo sapiens 57972 R-HSA-893593 https://reactome.org/PathwayBrowser/#/R-HSA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine TAS Homo sapiens 57972 R-HSA-893596 https://reactome.org/PathwayBrowser/#/R-HSA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu TAS Homo sapiens 57972 R-HSA-893616 https://reactome.org/PathwayBrowser/#/R-HSA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine TAS Homo sapiens 57972 R-HSA-901097 https://reactome.org/PathwayBrowser/#/R-HSA-901097 kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2] IEA Homo sapiens 57972 R-HSA-904864 https://reactome.org/PathwayBrowser/#/R-HSA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate TAS Homo sapiens 57972 R-HSA-909776 https://reactome.org/PathwayBrowser/#/R-HSA-909776 beta-alanine + pyruvate => 3-oxopropanoate + alanine IEA Homo sapiens 57972 R-HSA-909780 https://reactome.org/PathwayBrowser/#/R-HSA-909780 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine IEA Homo sapiens 57972 R-HSA-947499 https://reactome.org/PathwayBrowser/#/R-HSA-947499 Exchange of oxygen with sulfur in MoCo TAS Homo sapiens 57972 R-HSA-947514 https://reactome.org/PathwayBrowser/#/R-HSA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 TAS Homo sapiens 57972 R-MMU-1362408 https://reactome.org/PathwayBrowser/#/R-MMU-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Mus musculus 57972 R-MMU-209840 https://reactome.org/PathwayBrowser/#/R-MMU-209840 Two DITs combine to form thyroxine IEA Mus musculus 57972 R-MMU-209925 https://reactome.org/PathwayBrowser/#/R-MMU-209925 DIT and MIT combine to form triiodothyronine IEA Mus musculus 57972 R-MMU-2408524 https://reactome.org/PathwayBrowser/#/R-MMU-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Mus musculus 57972 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 57972 R-MMU-352108 https://reactome.org/PathwayBrowser/#/R-MMU-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Mus musculus 57972 R-MMU-352119 https://reactome.org/PathwayBrowser/#/R-MMU-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Mus musculus 57972 R-MMU-352174 https://reactome.org/PathwayBrowser/#/R-MMU-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Mus musculus 57972 R-MMU-352182 https://reactome.org/PathwayBrowser/#/R-MMU-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Mus musculus 57972 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 57972 R-MMU-352347 https://reactome.org/PathwayBrowser/#/R-MMU-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Mus musculus 57972 R-MMU-352354 https://reactome.org/PathwayBrowser/#/R-MMU-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Mus musculus 57972 R-MMU-352364 https://reactome.org/PathwayBrowser/#/R-MMU-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Mus musculus 57972 R-MMU-352371 https://reactome.org/PathwayBrowser/#/R-MMU-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Mus musculus 57972 R-MMU-352379 https://reactome.org/PathwayBrowser/#/R-MMU-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Mus musculus 57972 R-MMU-352385 https://reactome.org/PathwayBrowser/#/R-MMU-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Mus musculus 57972 R-MMU-375417 https://reactome.org/PathwayBrowser/#/R-MMU-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Mus musculus 57972 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 57972 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 57972 R-MMU-376200 https://reactome.org/PathwayBrowser/#/R-MMU-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Mus musculus 57972 R-MMU-389684 https://reactome.org/PathwayBrowser/#/R-MMU-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Mus musculus 57972 R-MMU-507749 https://reactome.org/PathwayBrowser/#/R-MMU-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Mus musculus 57972 R-MMU-507775 https://reactome.org/PathwayBrowser/#/R-MMU-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Mus musculus 57972 R-MMU-70523 https://reactome.org/PathwayBrowser/#/R-MMU-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Mus musculus 57972 R-MMU-70524 https://reactome.org/PathwayBrowser/#/R-MMU-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Mus musculus 57972 R-MMU-71217 https://reactome.org/PathwayBrowser/#/R-MMU-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Mus musculus 57972 R-MMU-893593 https://reactome.org/PathwayBrowser/#/R-MMU-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Mus musculus 57972 R-MMU-893596 https://reactome.org/PathwayBrowser/#/R-MMU-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Mus musculus 57972 R-MMU-893616 https://reactome.org/PathwayBrowser/#/R-MMU-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Mus musculus 57972 R-MMU-904864 https://reactome.org/PathwayBrowser/#/R-MMU-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Mus musculus 57972 R-MMU-947499 https://reactome.org/PathwayBrowser/#/R-MMU-947499 Exchange of oxygen with sulfur in MoCo IEA Mus musculus 57972 R-MMU-947514 https://reactome.org/PathwayBrowser/#/R-MMU-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Mus musculus 57972 R-PFA-1362408 https://reactome.org/PathwayBrowser/#/R-PFA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Plasmodium falciparum 57972 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 57972 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57972 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 57972 R-PFA-947514 https://reactome.org/PathwayBrowser/#/R-PFA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Plasmodium falciparum 57972 R-RNO-1362408 https://reactome.org/PathwayBrowser/#/R-RNO-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Rattus norvegicus 57972 R-RNO-209840 https://reactome.org/PathwayBrowser/#/R-RNO-209840 Two DITs combine to form thyroxine IEA Rattus norvegicus 57972 R-RNO-209925 https://reactome.org/PathwayBrowser/#/R-RNO-209925 DIT and MIT combine to form triiodothyronine IEA Rattus norvegicus 57972 R-RNO-2408524 https://reactome.org/PathwayBrowser/#/R-RNO-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Rattus norvegicus 57972 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 57972 R-RNO-352108 https://reactome.org/PathwayBrowser/#/R-RNO-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Rattus norvegicus 57972 R-RNO-352119 https://reactome.org/PathwayBrowser/#/R-RNO-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Rattus norvegicus 57972 R-RNO-352174 https://reactome.org/PathwayBrowser/#/R-RNO-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Rattus norvegicus 57972 R-RNO-352182 https://reactome.org/PathwayBrowser/#/R-RNO-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Rattus norvegicus 57972 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 57972 R-RNO-352347 https://reactome.org/PathwayBrowser/#/R-RNO-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Rattus norvegicus 57972 R-RNO-352354 https://reactome.org/PathwayBrowser/#/R-RNO-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Rattus norvegicus 57972 R-RNO-352364 https://reactome.org/PathwayBrowser/#/R-RNO-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Rattus norvegicus 57972 R-RNO-352371 https://reactome.org/PathwayBrowser/#/R-RNO-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Rattus norvegicus 57972 R-RNO-352379 https://reactome.org/PathwayBrowser/#/R-RNO-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Rattus norvegicus 57972 R-RNO-352385 https://reactome.org/PathwayBrowser/#/R-RNO-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Rattus norvegicus 57972 R-RNO-375417 https://reactome.org/PathwayBrowser/#/R-RNO-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Rattus norvegicus 57972 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 57972 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 57972 R-RNO-376200 https://reactome.org/PathwayBrowser/#/R-RNO-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Rattus norvegicus 57972 R-RNO-389684 https://reactome.org/PathwayBrowser/#/R-RNO-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Rattus norvegicus 57972 R-RNO-507749 https://reactome.org/PathwayBrowser/#/R-RNO-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Rattus norvegicus 57972 R-RNO-507775 https://reactome.org/PathwayBrowser/#/R-RNO-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Rattus norvegicus 57972 R-RNO-70523 https://reactome.org/PathwayBrowser/#/R-RNO-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Rattus norvegicus 57972 R-RNO-70524 https://reactome.org/PathwayBrowser/#/R-RNO-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Rattus norvegicus 57972 R-RNO-71217 https://reactome.org/PathwayBrowser/#/R-RNO-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Rattus norvegicus 57972 R-RNO-893593 https://reactome.org/PathwayBrowser/#/R-RNO-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Rattus norvegicus 57972 R-RNO-893596 https://reactome.org/PathwayBrowser/#/R-RNO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Rattus norvegicus 57972 R-RNO-893616 https://reactome.org/PathwayBrowser/#/R-RNO-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Rattus norvegicus 57972 R-RNO-904864 https://reactome.org/PathwayBrowser/#/R-RNO-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Rattus norvegicus 57972 R-RNO-909762 https://reactome.org/PathwayBrowser/#/R-RNO-909762 beta-alanine + pyruvate => 3-oxopropanoate + alanine TAS Rattus norvegicus 57972 R-RNO-909775 https://reactome.org/PathwayBrowser/#/R-RNO-909775 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine TAS Rattus norvegicus 57972 R-RNO-947499 https://reactome.org/PathwayBrowser/#/R-RNO-947499 Exchange of oxygen with sulfur in MoCo IEA Rattus norvegicus 57972 R-RNO-947514 https://reactome.org/PathwayBrowser/#/R-RNO-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Rattus norvegicus 57972 R-SCE-1362408 https://reactome.org/PathwayBrowser/#/R-SCE-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Saccharomyces cerevisiae 57972 R-SCE-352108 https://reactome.org/PathwayBrowser/#/R-SCE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 57972 R-SCE-352119 https://reactome.org/PathwayBrowser/#/R-SCE-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 57972 R-SCE-352174 https://reactome.org/PathwayBrowser/#/R-SCE-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Saccharomyces cerevisiae 57972 R-SCE-352182 https://reactome.org/PathwayBrowser/#/R-SCE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Saccharomyces cerevisiae 57972 R-SCE-375417 https://reactome.org/PathwayBrowser/#/R-SCE-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Saccharomyces cerevisiae 57972 R-SCE-507749 https://reactome.org/PathwayBrowser/#/R-SCE-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Saccharomyces cerevisiae 57972 R-SCE-507775 https://reactome.org/PathwayBrowser/#/R-SCE-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Saccharomyces cerevisiae 57972 R-SCE-70523 https://reactome.org/PathwayBrowser/#/R-SCE-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Saccharomyces cerevisiae 57972 R-SCE-70524 https://reactome.org/PathwayBrowser/#/R-SCE-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Saccharomyces cerevisiae 57972 R-SCE-71217 https://reactome.org/PathwayBrowser/#/R-SCE-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Saccharomyces cerevisiae 57972 R-SCE-893593 https://reactome.org/PathwayBrowser/#/R-SCE-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Saccharomyces cerevisiae 57972 R-SCE-893596 https://reactome.org/PathwayBrowser/#/R-SCE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Saccharomyces cerevisiae 57972 R-SCE-893616 https://reactome.org/PathwayBrowser/#/R-SCE-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Saccharomyces cerevisiae 57972 R-SCE-947514 https://reactome.org/PathwayBrowser/#/R-SCE-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Saccharomyces cerevisiae 57972 R-SPO-893593 https://reactome.org/PathwayBrowser/#/R-SPO-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Schizosaccharomyces pombe 57972 R-SPO-893596 https://reactome.org/PathwayBrowser/#/R-SPO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Schizosaccharomyces pombe 57972 R-SPO-893616 https://reactome.org/PathwayBrowser/#/R-SPO-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Schizosaccharomyces pombe 57972 R-SPO-904864 https://reactome.org/PathwayBrowser/#/R-SPO-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Schizosaccharomyces pombe 57972 R-SPO-947514 https://reactome.org/PathwayBrowser/#/R-SPO-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Schizosaccharomyces pombe 57972 R-SSC-1362408 https://reactome.org/PathwayBrowser/#/R-SSC-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Sus scrofa 57972 R-SSC-209840 https://reactome.org/PathwayBrowser/#/R-SSC-209840 Two DITs combine to form thyroxine IEA Sus scrofa 57972 R-SSC-209925 https://reactome.org/PathwayBrowser/#/R-SSC-209925 DIT and MIT combine to form triiodothyronine IEA Sus scrofa 57972 R-SSC-2408524 https://reactome.org/PathwayBrowser/#/R-SSC-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Sus scrofa 57972 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 57972 R-SSC-352108 https://reactome.org/PathwayBrowser/#/R-SSC-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Sus scrofa 57972 R-SSC-352119 https://reactome.org/PathwayBrowser/#/R-SSC-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Sus scrofa 57972 R-SSC-352174 https://reactome.org/PathwayBrowser/#/R-SSC-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Sus scrofa 57972 R-SSC-352182 https://reactome.org/PathwayBrowser/#/R-SSC-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Sus scrofa 57972 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 57972 R-SSC-352347 https://reactome.org/PathwayBrowser/#/R-SSC-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Sus scrofa 57972 R-SSC-352354 https://reactome.org/PathwayBrowser/#/R-SSC-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Sus scrofa 57972 R-SSC-352364 https://reactome.org/PathwayBrowser/#/R-SSC-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Sus scrofa 57972 R-SSC-352371 https://reactome.org/PathwayBrowser/#/R-SSC-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Sus scrofa 57972 R-SSC-352379 https://reactome.org/PathwayBrowser/#/R-SSC-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Sus scrofa 57972 R-SSC-352385 https://reactome.org/PathwayBrowser/#/R-SSC-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Sus scrofa 57972 R-SSC-375417 https://reactome.org/PathwayBrowser/#/R-SSC-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Sus scrofa 57972 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 57972 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 57972 R-SSC-376200 https://reactome.org/PathwayBrowser/#/R-SSC-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Sus scrofa 57972 R-SSC-389684 https://reactome.org/PathwayBrowser/#/R-SSC-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Sus scrofa 57972 R-SSC-507749 https://reactome.org/PathwayBrowser/#/R-SSC-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Sus scrofa 57972 R-SSC-507775 https://reactome.org/PathwayBrowser/#/R-SSC-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Sus scrofa 57972 R-SSC-70523 https://reactome.org/PathwayBrowser/#/R-SSC-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Sus scrofa 57972 R-SSC-70524 https://reactome.org/PathwayBrowser/#/R-SSC-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Sus scrofa 57972 R-SSC-71217 https://reactome.org/PathwayBrowser/#/R-SSC-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Sus scrofa 57972 R-SSC-893593 https://reactome.org/PathwayBrowser/#/R-SSC-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Sus scrofa 57972 R-SSC-893596 https://reactome.org/PathwayBrowser/#/R-SSC-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Sus scrofa 57972 R-SSC-893616 https://reactome.org/PathwayBrowser/#/R-SSC-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Sus scrofa 57972 R-SSC-904864 https://reactome.org/PathwayBrowser/#/R-SSC-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Sus scrofa 57972 R-SSC-947499 https://reactome.org/PathwayBrowser/#/R-SSC-947499 Exchange of oxygen with sulfur in MoCo IEA Sus scrofa 57972 R-SSC-947514 https://reactome.org/PathwayBrowser/#/R-SSC-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Sus scrofa 57972 R-XTR-1362408 https://reactome.org/PathwayBrowser/#/R-XTR-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Xenopus tropicalis 57972 R-XTR-2408524 https://reactome.org/PathwayBrowser/#/R-XTR-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Xenopus tropicalis 57972 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 57972 R-XTR-352108 https://reactome.org/PathwayBrowser/#/R-XTR-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57972 R-XTR-352119 https://reactome.org/PathwayBrowser/#/R-XTR-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57972 R-XTR-352174 https://reactome.org/PathwayBrowser/#/R-XTR-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Xenopus tropicalis 57972 R-XTR-352182 https://reactome.org/PathwayBrowser/#/R-XTR-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Xenopus tropicalis 57972 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 57972 R-XTR-352347 https://reactome.org/PathwayBrowser/#/R-XTR-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine IEA Xenopus tropicalis 57972 R-XTR-352354 https://reactome.org/PathwayBrowser/#/R-XTR-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine IEA Xenopus tropicalis 57972 R-XTR-352364 https://reactome.org/PathwayBrowser/#/R-XTR-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine IEA Xenopus tropicalis 57972 R-XTR-352371 https://reactome.org/PathwayBrowser/#/R-XTR-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine IEA Xenopus tropicalis 57972 R-XTR-352379 https://reactome.org/PathwayBrowser/#/R-XTR-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Xenopus tropicalis 57972 R-XTR-352385 https://reactome.org/PathwayBrowser/#/R-XTR-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Xenopus tropicalis 57972 R-XTR-375417 https://reactome.org/PathwayBrowser/#/R-XTR-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Xenopus tropicalis 57972 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57972 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 57972 R-XTR-376200 https://reactome.org/PathwayBrowser/#/R-XTR-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Xenopus tropicalis 57972 R-XTR-389684 https://reactome.org/PathwayBrowser/#/R-XTR-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Xenopus tropicalis 57972 R-XTR-507749 https://reactome.org/PathwayBrowser/#/R-XTR-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Xenopus tropicalis 57972 R-XTR-507775 https://reactome.org/PathwayBrowser/#/R-XTR-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Xenopus tropicalis 57972 R-XTR-70523 https://reactome.org/PathwayBrowser/#/R-XTR-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Xenopus tropicalis 57972 R-XTR-70524 https://reactome.org/PathwayBrowser/#/R-XTR-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Xenopus tropicalis 57972 R-XTR-71217 https://reactome.org/PathwayBrowser/#/R-XTR-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine IEA Xenopus tropicalis 57972 R-XTR-893593 https://reactome.org/PathwayBrowser/#/R-XTR-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Xenopus tropicalis 57972 R-XTR-893596 https://reactome.org/PathwayBrowser/#/R-XTR-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Xenopus tropicalis 57972 R-XTR-893616 https://reactome.org/PathwayBrowser/#/R-XTR-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Xenopus tropicalis 57972 R-XTR-904864 https://reactome.org/PathwayBrowser/#/R-XTR-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Xenopus tropicalis 57972 R-XTR-947514 https://reactome.org/PathwayBrowser/#/R-XTR-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Xenopus tropicalis 57977 R-BTA-159194 https://reactome.org/PathwayBrowser/#/R-BTA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Bos taurus 57977 R-BTA-189384 https://reactome.org/PathwayBrowser/#/R-BTA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Bos taurus 57977 R-BTA-400143 https://reactome.org/PathwayBrowser/#/R-BTA-400143 Fatty acid ligands activate PPARA IEA Bos taurus 57977 R-BTA-9661397 https://reactome.org/PathwayBrowser/#/R-BTA-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Bos taurus 57977 R-BTA-9661405 https://reactome.org/PathwayBrowser/#/R-BTA-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Bos taurus 57977 R-BTA-9661425 https://reactome.org/PathwayBrowser/#/R-BTA-9661425 BIL:ALB dissociates IEA Bos taurus 57977 R-BTA-9661432 https://reactome.org/PathwayBrowser/#/R-BTA-9661432 BIL binds ALB IEA Bos taurus 57977 R-BTA-9661723 https://reactome.org/PathwayBrowser/#/R-BTA-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Bos taurus 57977 R-BTA-9661799 https://reactome.org/PathwayBrowser/#/R-BTA-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Bos taurus 57977 R-BTA-9663492 https://reactome.org/PathwayBrowser/#/R-BTA-9663492 BIL dissociates from GSTA1, FABP1 IEA Bos taurus 57977 R-BTA-9663511 https://reactome.org/PathwayBrowser/#/R-BTA-9663511 BIL binds GSTA1, FABP1 IEA Bos taurus 57977 R-BTA-9709883 https://reactome.org/PathwayBrowser/#/R-BTA-9709883 BIL:ALB scavenges O2.- IEA Bos taurus 57977 R-CEL-9661397 https://reactome.org/PathwayBrowser/#/R-CEL-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Caenorhabditis elegans 57977 R-CEL-9661405 https://reactome.org/PathwayBrowser/#/R-CEL-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Caenorhabditis elegans 57977 R-CEL-9661723 https://reactome.org/PathwayBrowser/#/R-CEL-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Caenorhabditis elegans 57977 R-CEL-9661799 https://reactome.org/PathwayBrowser/#/R-CEL-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Caenorhabditis elegans 57977 R-CEL-9663492 https://reactome.org/PathwayBrowser/#/R-CEL-9663492 BIL dissociates from GSTA1, FABP1 IEA Caenorhabditis elegans 57977 R-CEL-9663511 https://reactome.org/PathwayBrowser/#/R-CEL-9663511 BIL binds GSTA1, FABP1 IEA Caenorhabditis elegans 57977 R-CFA-189384 https://reactome.org/PathwayBrowser/#/R-CFA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Canis familiaris 57977 R-CFA-400143 https://reactome.org/PathwayBrowser/#/R-CFA-400143 Fatty acid ligands activate PPARA IEA Canis familiaris 57977 R-CFA-9661397 https://reactome.org/PathwayBrowser/#/R-CFA-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Canis familiaris 57977 R-CFA-9661405 https://reactome.org/PathwayBrowser/#/R-CFA-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Canis familiaris 57977 R-CFA-9661425 https://reactome.org/PathwayBrowser/#/R-CFA-9661425 BIL:ALB dissociates IEA Canis familiaris 57977 R-CFA-9661432 https://reactome.org/PathwayBrowser/#/R-CFA-9661432 BIL binds ALB IEA Canis familiaris 57977 R-CFA-9661723 https://reactome.org/PathwayBrowser/#/R-CFA-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Canis familiaris 57977 R-CFA-9661799 https://reactome.org/PathwayBrowser/#/R-CFA-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Canis familiaris 57977 R-CFA-9663492 https://reactome.org/PathwayBrowser/#/R-CFA-9663492 BIL dissociates from GSTA1, FABP1 IEA Canis familiaris 57977 R-CFA-9663511 https://reactome.org/PathwayBrowser/#/R-CFA-9663511 BIL binds GSTA1, FABP1 IEA Canis familiaris 57977 R-CFA-9709883 https://reactome.org/PathwayBrowser/#/R-CFA-9709883 BIL:ALB scavenges O2.- IEA Canis familiaris 57977 R-DDI-159194 https://reactome.org/PathwayBrowser/#/R-DDI-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Dictyostelium discoideum 57977 R-DDI-9632039 https://reactome.org/PathwayBrowser/#/R-DDI-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Dictyostelium discoideum 57977 R-DDI-9661405 https://reactome.org/PathwayBrowser/#/R-DDI-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Dictyostelium discoideum 57977 R-DDI-9663492 https://reactome.org/PathwayBrowser/#/R-DDI-9663492 BIL dissociates from GSTA1, FABP1 IEA Dictyostelium discoideum 57977 R-DDI-9663511 https://reactome.org/PathwayBrowser/#/R-DDI-9663511 BIL binds GSTA1, FABP1 IEA Dictyostelium discoideum 57977 R-DME-189384 https://reactome.org/PathwayBrowser/#/R-DME-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Drosophila melanogaster 57977 R-DME-400143 https://reactome.org/PathwayBrowser/#/R-DME-400143 Fatty acid ligands activate PPARA IEA Drosophila melanogaster 57977 R-DME-9661397 https://reactome.org/PathwayBrowser/#/R-DME-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Drosophila melanogaster 57977 R-DME-9661405 https://reactome.org/PathwayBrowser/#/R-DME-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Drosophila melanogaster 57977 R-DME-9661723 https://reactome.org/PathwayBrowser/#/R-DME-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Drosophila melanogaster 57977 R-DME-9661799 https://reactome.org/PathwayBrowser/#/R-DME-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Drosophila melanogaster 57977 R-DME-9663492 https://reactome.org/PathwayBrowser/#/R-DME-9663492 BIL dissociates from GSTA1, FABP1 IEA Drosophila melanogaster 57977 R-DME-9663511 https://reactome.org/PathwayBrowser/#/R-DME-9663511 BIL binds GSTA1, FABP1 IEA Drosophila melanogaster 57977 R-DRE-189384 https://reactome.org/PathwayBrowser/#/R-DRE-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Danio rerio 57977 R-DRE-400143 https://reactome.org/PathwayBrowser/#/R-DRE-400143 Fatty acid ligands activate PPARA IEA Danio rerio 57977 R-DRE-9661397 https://reactome.org/PathwayBrowser/#/R-DRE-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Danio rerio 57977 R-DRE-9661723 https://reactome.org/PathwayBrowser/#/R-DRE-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Danio rerio 57977 R-DRE-9661799 https://reactome.org/PathwayBrowser/#/R-DRE-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Danio rerio 57977 R-DRE-9663492 https://reactome.org/PathwayBrowser/#/R-DRE-9663492 BIL dissociates from GSTA1, FABP1 IEA Danio rerio 57977 R-DRE-9663511 https://reactome.org/PathwayBrowser/#/R-DRE-9663511 BIL binds GSTA1, FABP1 IEA Danio rerio 57977 R-GGA-159194 https://reactome.org/PathwayBrowser/#/R-GGA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Gallus gallus 57977 R-GGA-189384 https://reactome.org/PathwayBrowser/#/R-GGA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Gallus gallus 57977 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus 57977 R-GGA-9632039 https://reactome.org/PathwayBrowser/#/R-GGA-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Gallus gallus 57977 R-GGA-9661397 https://reactome.org/PathwayBrowser/#/R-GGA-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Gallus gallus 57977 R-GGA-9661405 https://reactome.org/PathwayBrowser/#/R-GGA-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Gallus gallus 57977 R-GGA-9661425 https://reactome.org/PathwayBrowser/#/R-GGA-9661425 BIL:ALB dissociates IEA Gallus gallus 57977 R-GGA-9661432 https://reactome.org/PathwayBrowser/#/R-GGA-9661432 BIL binds ALB IEA Gallus gallus 57977 R-GGA-9661723 https://reactome.org/PathwayBrowser/#/R-GGA-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Gallus gallus 57977 R-GGA-9661799 https://reactome.org/PathwayBrowser/#/R-GGA-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Gallus gallus 57977 R-GGA-9663492 https://reactome.org/PathwayBrowser/#/R-GGA-9663492 BIL dissociates from GSTA1, FABP1 IEA Gallus gallus 57977 R-GGA-9663511 https://reactome.org/PathwayBrowser/#/R-GGA-9663511 BIL binds GSTA1, FABP1 IEA Gallus gallus 57977 R-GGA-9709883 https://reactome.org/PathwayBrowser/#/R-GGA-9709883 BIL:ALB scavenges O2.- IEA Gallus gallus 57977 R-HSA-1368065 https://reactome.org/PathwayBrowser/#/R-HSA-1368065 Expression of NPAS2 IEA Homo sapiens 57977 R-HSA-159194 https://reactome.org/PathwayBrowser/#/R-HSA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG TAS Homo sapiens 57977 R-HSA-1592238 https://reactome.org/PathwayBrowser/#/R-HSA-1592238 Expression of ALAS1 TAS Homo sapiens 57977 R-HSA-1655826 https://reactome.org/PathwayBrowser/#/R-HSA-1655826 Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) TAS Homo sapiens 57977 R-HSA-1655848 https://reactome.org/PathwayBrowser/#/R-HSA-1655848 Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) TAS Homo sapiens 57977 R-HSA-1655850 https://reactome.org/PathwayBrowser/#/R-HSA-1655850 Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) TAS Homo sapiens 57977 R-HSA-1801587 https://reactome.org/PathwayBrowser/#/R-HSA-1801587 Expression of CPT1A IEA Homo sapiens 57977 R-HSA-189381 https://reactome.org/PathwayBrowser/#/R-HSA-189381 BIL translocates from the cytosol to the ER lumen TAS Homo sapiens 57977 R-HSA-189384 https://reactome.org/PathwayBrowser/#/R-HSA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL TAS Homo sapiens 57977 R-HSA-1989745 https://reactome.org/PathwayBrowser/#/R-HSA-1989745 Expression of ACADM TAS Homo sapiens 57977 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 57977 R-HSA-1989747 https://reactome.org/PathwayBrowser/#/R-HSA-1989747 Expression of FHL2 TAS Homo sapiens 57977 R-HSA-1989748 https://reactome.org/PathwayBrowser/#/R-HSA-1989748 Expression of GRHL1 TAS Homo sapiens 57977 R-HSA-1989749 https://reactome.org/PathwayBrowser/#/R-HSA-1989749 Expression of ACOX1 TAS Homo sapiens 57977 R-HSA-1989750 https://reactome.org/PathwayBrowser/#/R-HSA-1989750 Expression of FATP1 (SLC27A1) TAS Homo sapiens 57977 R-HSA-1989751 https://reactome.org/PathwayBrowser/#/R-HSA-1989751 Expression of FABP1 TAS Homo sapiens 57977 R-HSA-1989752 https://reactome.org/PathwayBrowser/#/R-HSA-1989752 Expression of TXNRD1 TAS Homo sapiens 57977 R-HSA-1989753 https://reactome.org/PathwayBrowser/#/R-HSA-1989753 Expression of PEX11A TAS Homo sapiens 57977 R-HSA-1989754 https://reactome.org/PathwayBrowser/#/R-HSA-1989754 Expression of APOA1 TAS Homo sapiens 57977 R-HSA-1989755 https://reactome.org/PathwayBrowser/#/R-HSA-1989755 Expression of CYP4A11 TAS Homo sapiens 57977 R-HSA-1989756 https://reactome.org/PathwayBrowser/#/R-HSA-1989756 Expression of ME1 TAS Homo sapiens 57977 R-HSA-1989757 https://reactome.org/PathwayBrowser/#/R-HSA-1989757 Expression of FADS1 TAS Homo sapiens 57977 R-HSA-1989758 https://reactome.org/PathwayBrowser/#/R-HSA-1989758 Expression of UGT1A9 TAS Homo sapiens 57977 R-HSA-1989759 https://reactome.org/PathwayBrowser/#/R-HSA-1989759 Expression of G0S2 TAS Homo sapiens 57977 R-HSA-1989760 https://reactome.org/PathwayBrowser/#/R-HSA-1989760 Expression of HMGCS2 TAS Homo sapiens 57977 R-HSA-1989761 https://reactome.org/PathwayBrowser/#/R-HSA-1989761 Expression of APOA5 TAS Homo sapiens 57977 R-HSA-1989762 https://reactome.org/PathwayBrowser/#/R-HSA-1989762 Expression of ABCB4 TAS Homo sapiens 57977 R-HSA-1989764 https://reactome.org/PathwayBrowser/#/R-HSA-1989764 Expression of CYP1A1 TAS Homo sapiens 57977 R-HSA-1989765 https://reactome.org/PathwayBrowser/#/R-HSA-1989765 Expression of ABCA1 TAS Homo sapiens 57977 R-HSA-1989767 https://reactome.org/PathwayBrowser/#/R-HSA-1989767 Expression of TRIB3 TAS Homo sapiens 57977 R-HSA-1989768 https://reactome.org/PathwayBrowser/#/R-HSA-1989768 Expression of TIAM2 TAS Homo sapiens 57977 R-HSA-1989770 https://reactome.org/PathwayBrowser/#/R-HSA-1989770 Expression of PLIN2 TAS Homo sapiens 57977 R-HSA-1989771 https://reactome.org/PathwayBrowser/#/R-HSA-1989771 Expression of TNFRSF21 TAS Homo sapiens 57977 R-HSA-1989772 https://reactome.org/PathwayBrowser/#/R-HSA-1989772 Expression of GLIPR1 TAS Homo sapiens 57977 R-HSA-1989773 https://reactome.org/PathwayBrowser/#/R-HSA-1989773 Expression of CPT2 TAS Homo sapiens 57977 R-HSA-1989774 https://reactome.org/PathwayBrowser/#/R-HSA-1989774 Expression of AGT TAS Homo sapiens 57977 R-HSA-1989775 https://reactome.org/PathwayBrowser/#/R-HSA-1989775 Expression of SULT2A1 TAS Homo sapiens 57977 R-HSA-1989776 https://reactome.org/PathwayBrowser/#/R-HSA-1989776 Expression of APOA2 TAS Homo sapiens 57977 R-HSA-1989777 https://reactome.org/PathwayBrowser/#/R-HSA-1989777 Expression of RGL1 TAS Homo sapiens 57977 R-HSA-1989778 https://reactome.org/PathwayBrowser/#/R-HSA-1989778 Expression of ACSL1 TAS Homo sapiens 57977 R-HSA-1989779 https://reactome.org/PathwayBrowser/#/R-HSA-1989779 Expression of ANKRD1 TAS Homo sapiens 57977 R-HSA-400143 https://reactome.org/PathwayBrowser/#/R-HSA-400143 Fatty acid ligands activate PPARA TAS Homo sapiens 57977 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 57977 R-HSA-5604954 https://reactome.org/PathwayBrowser/#/R-HSA-5604954 Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BIL TAS Homo sapiens 57977 R-HSA-5604975 https://reactome.org/PathwayBrowser/#/R-HSA-5604975 Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BIL TAS Homo sapiens 57977 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 57977 R-HSA-5661184 https://reactome.org/PathwayBrowser/#/R-HSA-5661184 Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte) TAS Homo sapiens 57977 R-HSA-5661198 https://reactome.org/PathwayBrowser/#/R-HSA-5661198 Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte) TAS Homo sapiens 57977 R-HSA-879724 https://reactome.org/PathwayBrowser/#/R-HSA-879724 Expression of PPARA IEA Homo sapiens 57977 R-HSA-9632039 https://reactome.org/PathwayBrowser/#/R-HSA-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG TAS Homo sapiens 57977 R-HSA-9661397 https://reactome.org/PathwayBrowser/#/R-HSA-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) TAS Homo sapiens 57977 R-HSA-9661405 https://reactome.org/PathwayBrowser/#/R-HSA-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) TAS Homo sapiens 57977 R-HSA-9661425 https://reactome.org/PathwayBrowser/#/R-HSA-9661425 BIL:ALB dissociates TAS Homo sapiens 57977 R-HSA-9661432 https://reactome.org/PathwayBrowser/#/R-HSA-9661432 BIL binds ALB TAS Homo sapiens 57977 R-HSA-9661723 https://reactome.org/PathwayBrowser/#/R-HSA-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) TAS Homo sapiens 57977 R-HSA-9661745 https://reactome.org/PathwayBrowser/#/R-HSA-9661745 An unknown BILR reduces BIL to D-UBGN TAS Homo sapiens 57977 R-HSA-9661799 https://reactome.org/PathwayBrowser/#/R-HSA-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) TAS Homo sapiens 57977 R-HSA-9661820 https://reactome.org/PathwayBrowser/#/R-HSA-9661820 Bacterial GUSB hydrolyses BDG to BIL TAS Homo sapiens 57977 R-HSA-9663492 https://reactome.org/PathwayBrowser/#/R-HSA-9663492 BIL dissociates from GSTA1, FABP1 TAS Homo sapiens 57977 R-HSA-9663511 https://reactome.org/PathwayBrowser/#/R-HSA-9663511 BIL binds GSTA1, FABP1 TAS Homo sapiens 57977 R-HSA-9709878 https://reactome.org/PathwayBrowser/#/R-HSA-9709878 BIL translocates to the nucleus TAS Homo sapiens 57977 R-HSA-9709879 https://reactome.org/PathwayBrowser/#/R-HSA-9709879 BIL scavenges O2.- TAS Homo sapiens 57977 R-HSA-9709883 https://reactome.org/PathwayBrowser/#/R-HSA-9709883 BIL:ALB scavenges O2.- TAS Homo sapiens 57977 R-HSA-9709885 https://reactome.org/PathwayBrowser/#/R-HSA-9709885 BIL scavenges NO TAS Homo sapiens 57977 R-MMU-159194 https://reactome.org/PathwayBrowser/#/R-MMU-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Mus musculus 57977 R-MMU-189384 https://reactome.org/PathwayBrowser/#/R-MMU-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Mus musculus 57977 R-MMU-400143 https://reactome.org/PathwayBrowser/#/R-MMU-400143 Fatty acid ligands activate PPARA IEA Mus musculus 57977 R-MMU-9632039 https://reactome.org/PathwayBrowser/#/R-MMU-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Mus musculus 57977 R-MMU-9661397 https://reactome.org/PathwayBrowser/#/R-MMU-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Mus musculus 57977 R-MMU-9661405 https://reactome.org/PathwayBrowser/#/R-MMU-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Mus musculus 57977 R-MMU-9661425 https://reactome.org/PathwayBrowser/#/R-MMU-9661425 BIL:ALB dissociates IEA Mus musculus 57977 R-MMU-9661432 https://reactome.org/PathwayBrowser/#/R-MMU-9661432 BIL binds ALB IEA Mus musculus 57977 R-MMU-9661723 https://reactome.org/PathwayBrowser/#/R-MMU-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Mus musculus 57977 R-MMU-9661799 https://reactome.org/PathwayBrowser/#/R-MMU-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Mus musculus 57977 R-MMU-9663492 https://reactome.org/PathwayBrowser/#/R-MMU-9663492 BIL dissociates from GSTA1, FABP1 IEA Mus musculus 57977 R-MMU-9663511 https://reactome.org/PathwayBrowser/#/R-MMU-9663511 BIL binds GSTA1, FABP1 IEA Mus musculus 57977 R-MMU-9709883 https://reactome.org/PathwayBrowser/#/R-MMU-9709883 BIL:ALB scavenges O2.- IEA Mus musculus 57977 R-PFA-9663492 https://reactome.org/PathwayBrowser/#/R-PFA-9663492 BIL dissociates from GSTA1, FABP1 IEA Plasmodium falciparum 57977 R-PFA-9663511 https://reactome.org/PathwayBrowser/#/R-PFA-9663511 BIL binds GSTA1, FABP1 IEA Plasmodium falciparum 57977 R-RNO-159194 https://reactome.org/PathwayBrowser/#/R-RNO-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Rattus norvegicus 57977 R-RNO-189384 https://reactome.org/PathwayBrowser/#/R-RNO-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Rattus norvegicus 57977 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus 57977 R-RNO-9632039 https://reactome.org/PathwayBrowser/#/R-RNO-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Rattus norvegicus 57977 R-RNO-9661397 https://reactome.org/PathwayBrowser/#/R-RNO-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Rattus norvegicus 57977 R-RNO-9661405 https://reactome.org/PathwayBrowser/#/R-RNO-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Rattus norvegicus 57977 R-RNO-9661425 https://reactome.org/PathwayBrowser/#/R-RNO-9661425 BIL:ALB dissociates IEA Rattus norvegicus 57977 R-RNO-9661432 https://reactome.org/PathwayBrowser/#/R-RNO-9661432 BIL binds ALB IEA Rattus norvegicus 57977 R-RNO-9661723 https://reactome.org/PathwayBrowser/#/R-RNO-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Rattus norvegicus 57977 R-RNO-9661799 https://reactome.org/PathwayBrowser/#/R-RNO-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Rattus norvegicus 57977 R-RNO-9663492 https://reactome.org/PathwayBrowser/#/R-RNO-9663492 BIL dissociates from GSTA1, FABP1 IEA Rattus norvegicus 57977 R-RNO-9663511 https://reactome.org/PathwayBrowser/#/R-RNO-9663511 BIL binds GSTA1, FABP1 IEA Rattus norvegicus 57977 R-RNO-9709883 https://reactome.org/PathwayBrowser/#/R-RNO-9709883 BIL:ALB scavenges O2.- IEA Rattus norvegicus 57977 R-SCE-9661405 https://reactome.org/PathwayBrowser/#/R-SCE-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Saccharomyces cerevisiae 57977 R-SPO-9661405 https://reactome.org/PathwayBrowser/#/R-SPO-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Schizosaccharomyces pombe 57977 R-SSC-159194 https://reactome.org/PathwayBrowser/#/R-SSC-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Sus scrofa 57977 R-SSC-189384 https://reactome.org/PathwayBrowser/#/R-SSC-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Sus scrofa 57977 R-SSC-9661397 https://reactome.org/PathwayBrowser/#/R-SSC-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Sus scrofa 57977 R-SSC-9661405 https://reactome.org/PathwayBrowser/#/R-SSC-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Sus scrofa 57977 R-SSC-9661425 https://reactome.org/PathwayBrowser/#/R-SSC-9661425 BIL:ALB dissociates IEA Sus scrofa 57977 R-SSC-9661432 https://reactome.org/PathwayBrowser/#/R-SSC-9661432 BIL binds ALB IEA Sus scrofa 57977 R-SSC-9661723 https://reactome.org/PathwayBrowser/#/R-SSC-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Sus scrofa 57977 R-SSC-9661799 https://reactome.org/PathwayBrowser/#/R-SSC-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Sus scrofa 57977 R-SSC-9663492 https://reactome.org/PathwayBrowser/#/R-SSC-9663492 BIL dissociates from GSTA1, FABP1 IEA Sus scrofa 57977 R-SSC-9663511 https://reactome.org/PathwayBrowser/#/R-SSC-9663511 BIL binds GSTA1, FABP1 IEA Sus scrofa 57977 R-SSC-9709883 https://reactome.org/PathwayBrowser/#/R-SSC-9709883 BIL:ALB scavenges O2.- IEA Sus scrofa 57977 R-XTR-189384 https://reactome.org/PathwayBrowser/#/R-XTR-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Xenopus tropicalis 57977 R-XTR-9661397 https://reactome.org/PathwayBrowser/#/R-XTR-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Xenopus tropicalis 57977 R-XTR-9661405 https://reactome.org/PathwayBrowser/#/R-XTR-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Xenopus tropicalis 57977 R-XTR-9661425 https://reactome.org/PathwayBrowser/#/R-XTR-9661425 BIL:ALB dissociates IEA Xenopus tropicalis 57977 R-XTR-9661432 https://reactome.org/PathwayBrowser/#/R-XTR-9661432 BIL binds ALB IEA Xenopus tropicalis 57977 R-XTR-9661723 https://reactome.org/PathwayBrowser/#/R-XTR-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Xenopus tropicalis 57977 R-XTR-9661799 https://reactome.org/PathwayBrowser/#/R-XTR-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Xenopus tropicalis 57977 R-XTR-9663492 https://reactome.org/PathwayBrowser/#/R-XTR-9663492 BIL dissociates from GSTA1, FABP1 IEA Xenopus tropicalis 57977 R-XTR-9663511 https://reactome.org/PathwayBrowser/#/R-XTR-9663511 BIL binds GSTA1, FABP1 IEA Xenopus tropicalis 57977 R-XTR-9709883 https://reactome.org/PathwayBrowser/#/R-XTR-9709883 BIL:ALB scavenges O2.- IEA Xenopus tropicalis 57986 R-BTA-196950 https://reactome.org/PathwayBrowser/#/R-BTA-196950 2xTRAP hydrolyzes FMN to RIB IEA Bos taurus 57986 R-BTA-196964 https://reactome.org/PathwayBrowser/#/R-BTA-196964 RFK:Mg2+ phosphorylates RIB IEA Bos taurus 57986 R-BTA-3165230 https://reactome.org/PathwayBrowser/#/R-BTA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Bos taurus 57986 R-CEL-196950 https://reactome.org/PathwayBrowser/#/R-CEL-196950 2xTRAP hydrolyzes FMN to RIB IEA Caenorhabditis elegans 57986 R-CEL-196964 https://reactome.org/PathwayBrowser/#/R-CEL-196964 RFK:Mg2+ phosphorylates RIB IEA Caenorhabditis elegans 57986 R-CEL-3165230 https://reactome.org/PathwayBrowser/#/R-CEL-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Caenorhabditis elegans 57986 R-CFA-196950 https://reactome.org/PathwayBrowser/#/R-CFA-196950 2xTRAP hydrolyzes FMN to RIB IEA Canis familiaris 57986 R-CFA-196964 https://reactome.org/PathwayBrowser/#/R-CFA-196964 RFK:Mg2+ phosphorylates RIB IEA Canis familiaris 57986 R-CFA-3165230 https://reactome.org/PathwayBrowser/#/R-CFA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Canis familiaris 57986 R-DME-196964 https://reactome.org/PathwayBrowser/#/R-DME-196964 RFK:Mg2+ phosphorylates RIB IEA Drosophila melanogaster 57986 R-DME-3165230 https://reactome.org/PathwayBrowser/#/R-DME-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Drosophila melanogaster 57986 R-DRE-196950 https://reactome.org/PathwayBrowser/#/R-DRE-196950 2xTRAP hydrolyzes FMN to RIB IEA Danio rerio 57986 R-DRE-3165230 https://reactome.org/PathwayBrowser/#/R-DRE-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Danio rerio 57986 R-GGA-196950 https://reactome.org/PathwayBrowser/#/R-GGA-196950 2xTRAP hydrolyzes FMN to RIB IEA Gallus gallus 57986 R-GGA-196964 https://reactome.org/PathwayBrowser/#/R-GGA-196964 RFK:Mg2+ phosphorylates RIB IEA Gallus gallus 57986 R-GGA-3165230 https://reactome.org/PathwayBrowser/#/R-GGA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Gallus gallus 57986 R-HSA-196950 https://reactome.org/PathwayBrowser/#/R-HSA-196950 2xTRAP hydrolyzes FMN to RIB TAS Homo sapiens 57986 R-HSA-196964 https://reactome.org/PathwayBrowser/#/R-HSA-196964 RFK:Mg2+ phosphorylates RIB TAS Homo sapiens 57986 R-HSA-3165230 https://reactome.org/PathwayBrowser/#/R-HSA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol TAS Homo sapiens 57986 R-MMU-196950 https://reactome.org/PathwayBrowser/#/R-MMU-196950 2xTRAP hydrolyzes FMN to RIB IEA Mus musculus 57986 R-MMU-196964 https://reactome.org/PathwayBrowser/#/R-MMU-196964 RFK:Mg2+ phosphorylates RIB IEA Mus musculus 57986 R-MMU-3165230 https://reactome.org/PathwayBrowser/#/R-MMU-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Mus musculus 57986 R-PFA-196950 https://reactome.org/PathwayBrowser/#/R-PFA-196950 2xTRAP hydrolyzes FMN to RIB IEA Plasmodium falciparum 57986 R-PFA-196964 https://reactome.org/PathwayBrowser/#/R-PFA-196964 RFK:Mg2+ phosphorylates RIB IEA Plasmodium falciparum 57986 R-RNO-196950 https://reactome.org/PathwayBrowser/#/R-RNO-196950 2xTRAP hydrolyzes FMN to RIB IEA Rattus norvegicus 57986 R-RNO-196964 https://reactome.org/PathwayBrowser/#/R-RNO-196964 RFK:Mg2+ phosphorylates RIB IEA Rattus norvegicus 57986 R-RNO-3165230 https://reactome.org/PathwayBrowser/#/R-RNO-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Rattus norvegicus 57986 R-SCE-196964 https://reactome.org/PathwayBrowser/#/R-SCE-196964 RFK:Mg2+ phosphorylates RIB IEA Saccharomyces cerevisiae 57986 R-SPO-196964 https://reactome.org/PathwayBrowser/#/R-SPO-196964 RFK:Mg2+ phosphorylates RIB IEA Schizosaccharomyces pombe 57986 R-SSC-196950 https://reactome.org/PathwayBrowser/#/R-SSC-196950 2xTRAP hydrolyzes FMN to RIB IEA Sus scrofa 57986 R-SSC-196964 https://reactome.org/PathwayBrowser/#/R-SSC-196964 RFK:Mg2+ phosphorylates RIB IEA Sus scrofa 57986 R-SSC-3165230 https://reactome.org/PathwayBrowser/#/R-SSC-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Sus scrofa 57986 R-XTR-196964 https://reactome.org/PathwayBrowser/#/R-XTR-196964 RFK:Mg2+ phosphorylates RIB IEA Xenopus tropicalis 57986 R-XTR-3165230 https://reactome.org/PathwayBrowser/#/R-XTR-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Xenopus tropicalis 57991 R-BTA-189384 https://reactome.org/PathwayBrowser/#/R-BTA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Bos taurus 57991 R-BTA-189398 https://reactome.org/PathwayBrowser/#/R-BTA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Bos taurus 57991 R-BTA-9709883 https://reactome.org/PathwayBrowser/#/R-BTA-9709883 BIL:ALB scavenges O2.- IEA Bos taurus 57991 R-CFA-189384 https://reactome.org/PathwayBrowser/#/R-CFA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Canis familiaris 57991 R-CFA-189398 https://reactome.org/PathwayBrowser/#/R-CFA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Canis familiaris 57991 R-CFA-9709883 https://reactome.org/PathwayBrowser/#/R-CFA-9709883 BIL:ALB scavenges O2.- IEA Canis familiaris 57991 R-DME-189384 https://reactome.org/PathwayBrowser/#/R-DME-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Drosophila melanogaster 57991 R-DME-189398 https://reactome.org/PathwayBrowser/#/R-DME-189398 HMOX1 dimer, HMOX2 cleave heme IEA Drosophila melanogaster 57991 R-DRE-189384 https://reactome.org/PathwayBrowser/#/R-DRE-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Danio rerio 57991 R-DRE-189398 https://reactome.org/PathwayBrowser/#/R-DRE-189398 HMOX1 dimer, HMOX2 cleave heme IEA Danio rerio 57991 R-GGA-189384 https://reactome.org/PathwayBrowser/#/R-GGA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Gallus gallus 57991 R-GGA-189398 https://reactome.org/PathwayBrowser/#/R-GGA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Gallus gallus 57991 R-GGA-9709883 https://reactome.org/PathwayBrowser/#/R-GGA-9709883 BIL:ALB scavenges O2.- IEA Gallus gallus 57991 R-HSA-189384 https://reactome.org/PathwayBrowser/#/R-HSA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL TAS Homo sapiens 57991 R-HSA-189398 https://reactome.org/PathwayBrowser/#/R-HSA-189398 HMOX1 dimer, HMOX2 cleave heme TAS Homo sapiens 57991 R-HSA-9709883 https://reactome.org/PathwayBrowser/#/R-HSA-9709883 BIL:ALB scavenges O2.- TAS Homo sapiens 57991 R-MMU-189384 https://reactome.org/PathwayBrowser/#/R-MMU-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Mus musculus 57991 R-MMU-189398 https://reactome.org/PathwayBrowser/#/R-MMU-189398 HMOX1 dimer, HMOX2 cleave heme IEA Mus musculus 57991 R-MMU-9709883 https://reactome.org/PathwayBrowser/#/R-MMU-9709883 BIL:ALB scavenges O2.- IEA Mus musculus 57991 R-RNO-189384 https://reactome.org/PathwayBrowser/#/R-RNO-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Rattus norvegicus 57991 R-RNO-189398 https://reactome.org/PathwayBrowser/#/R-RNO-189398 HMOX1 dimer, HMOX2 cleave heme IEA Rattus norvegicus 57991 R-RNO-9709883 https://reactome.org/PathwayBrowser/#/R-RNO-9709883 BIL:ALB scavenges O2.- IEA Rattus norvegicus 57991 R-SSC-189384 https://reactome.org/PathwayBrowser/#/R-SSC-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Sus scrofa 57991 R-SSC-189398 https://reactome.org/PathwayBrowser/#/R-SSC-189398 HMOX1 dimer, HMOX2 cleave heme IEA Sus scrofa 57991 R-SSC-9709883 https://reactome.org/PathwayBrowser/#/R-SSC-9709883 BIL:ALB scavenges O2.- IEA Sus scrofa 57991 R-XTR-189384 https://reactome.org/PathwayBrowser/#/R-XTR-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Xenopus tropicalis 57991 R-XTR-189398 https://reactome.org/PathwayBrowser/#/R-XTR-189398 HMOX1 dimer, HMOX2 cleave heme IEA Xenopus tropicalis 57991 R-XTR-9709883 https://reactome.org/PathwayBrowser/#/R-XTR-9709883 BIL:ALB scavenges O2.- IEA Xenopus tropicalis 57997 R-BTA-162683 https://reactome.org/PathwayBrowser/#/R-BTA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Bos taurus 57997 R-BTA-162857 https://reactome.org/PathwayBrowser/#/R-BTA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Bos taurus 57997 R-CEL-162683 https://reactome.org/PathwayBrowser/#/R-CEL-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Caenorhabditis elegans 57997 R-CEL-162857 https://reactome.org/PathwayBrowser/#/R-CEL-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Caenorhabditis elegans 57997 R-CFA-162683 https://reactome.org/PathwayBrowser/#/R-CFA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Canis familiaris 57997 R-CFA-162857 https://reactome.org/PathwayBrowser/#/R-CFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Canis familiaris 57997 R-DDI-162683 https://reactome.org/PathwayBrowser/#/R-DDI-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Dictyostelium discoideum 57997 R-DDI-162857 https://reactome.org/PathwayBrowser/#/R-DDI-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Dictyostelium discoideum 57997 R-DME-162683 https://reactome.org/PathwayBrowser/#/R-DME-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Drosophila melanogaster 57997 R-DME-162857 https://reactome.org/PathwayBrowser/#/R-DME-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Drosophila melanogaster 57997 R-GGA-162683 https://reactome.org/PathwayBrowser/#/R-GGA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Gallus gallus 57997 R-GGA-162857 https://reactome.org/PathwayBrowser/#/R-GGA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Gallus gallus 57997 R-HSA-162683 https://reactome.org/PathwayBrowser/#/R-HSA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH TAS Homo sapiens 57997 R-HSA-162857 https://reactome.org/PathwayBrowser/#/R-HSA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate TAS Homo sapiens 57997 R-MMU-162683 https://reactome.org/PathwayBrowser/#/R-MMU-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Mus musculus 57997 R-MMU-162857 https://reactome.org/PathwayBrowser/#/R-MMU-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Mus musculus 57997 R-PFA-162683 https://reactome.org/PathwayBrowser/#/R-PFA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Plasmodium falciparum 57997 R-PFA-162857 https://reactome.org/PathwayBrowser/#/R-PFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Plasmodium falciparum 57997 R-RNO-162683 https://reactome.org/PathwayBrowser/#/R-RNO-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Rattus norvegicus 57997 R-RNO-162857 https://reactome.org/PathwayBrowser/#/R-RNO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Rattus norvegicus 57997 R-SCE-162683 https://reactome.org/PathwayBrowser/#/R-SCE-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Saccharomyces cerevisiae 57997 R-SCE-162857 https://reactome.org/PathwayBrowser/#/R-SCE-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Saccharomyces cerevisiae 57997 R-SPO-162683 https://reactome.org/PathwayBrowser/#/R-SPO-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Schizosaccharomyces pombe 57997 R-SPO-162857 https://reactome.org/PathwayBrowser/#/R-SPO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Schizosaccharomyces pombe 57997 R-SSC-162683 https://reactome.org/PathwayBrowser/#/R-SSC-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Sus scrofa 57997 R-SSC-162857 https://reactome.org/PathwayBrowser/#/R-SSC-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Sus scrofa 57997 R-XTR-162683 https://reactome.org/PathwayBrowser/#/R-XTR-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Xenopus tropicalis 57997 R-XTR-162857 https://reactome.org/PathwayBrowser/#/R-XTR-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Xenopus tropicalis 58017 R-BTA-111215 https://reactome.org/PathwayBrowser/#/R-BTA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Bos taurus 58017 R-BTA-111289 https://reactome.org/PathwayBrowser/#/R-BTA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Bos taurus 58017 R-BTA-197186 https://reactome.org/PathwayBrowser/#/R-BTA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Bos taurus 58017 R-BTA-197250 https://reactome.org/PathwayBrowser/#/R-BTA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Bos taurus 58017 R-BTA-197268 https://reactome.org/PathwayBrowser/#/R-BTA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Bos taurus 58017 R-BTA-73567 https://reactome.org/PathwayBrowser/#/R-BTA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Bos taurus 58017 R-BTA-73580 https://reactome.org/PathwayBrowser/#/R-BTA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Bos taurus 58017 R-BTA-73815 https://reactome.org/PathwayBrowser/#/R-BTA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Bos taurus 58017 R-BTA-74213 https://reactome.org/PathwayBrowser/#/R-BTA-74213 APRT catalyzes the conversion of adenine to AMP IEA Bos taurus 58017 R-BTA-74215 https://reactome.org/PathwayBrowser/#/R-BTA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Bos taurus 58017 R-BTA-9748951 https://reactome.org/PathwayBrowser/#/R-BTA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Bos taurus 58017 R-CEL-111289 https://reactome.org/PathwayBrowser/#/R-CEL-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Caenorhabditis elegans 58017 R-CEL-197186 https://reactome.org/PathwayBrowser/#/R-CEL-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Caenorhabditis elegans 58017 R-CEL-73567 https://reactome.org/PathwayBrowser/#/R-CEL-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Caenorhabditis elegans 58017 R-CEL-73815 https://reactome.org/PathwayBrowser/#/R-CEL-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Caenorhabditis elegans 58017 R-CEL-74213 https://reactome.org/PathwayBrowser/#/R-CEL-74213 APRT catalyzes the conversion of adenine to AMP IEA Caenorhabditis elegans 58017 R-CEL-74215 https://reactome.org/PathwayBrowser/#/R-CEL-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Caenorhabditis elegans 58017 R-CEL-9748951 https://reactome.org/PathwayBrowser/#/R-CEL-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Caenorhabditis elegans 58017 R-CFA-111215 https://reactome.org/PathwayBrowser/#/R-CFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Canis familiaris 58017 R-CFA-111289 https://reactome.org/PathwayBrowser/#/R-CFA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Canis familiaris 58017 R-CFA-197186 https://reactome.org/PathwayBrowser/#/R-CFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Canis familiaris 58017 R-CFA-197250 https://reactome.org/PathwayBrowser/#/R-CFA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Canis familiaris 58017 R-CFA-197268 https://reactome.org/PathwayBrowser/#/R-CFA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Canis familiaris 58017 R-CFA-73567 https://reactome.org/PathwayBrowser/#/R-CFA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Canis familiaris 58017 R-CFA-73580 https://reactome.org/PathwayBrowser/#/R-CFA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Canis familiaris 58017 R-CFA-73815 https://reactome.org/PathwayBrowser/#/R-CFA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Canis familiaris 58017 R-CFA-74213 https://reactome.org/PathwayBrowser/#/R-CFA-74213 APRT catalyzes the conversion of adenine to AMP IEA Canis familiaris 58017 R-CFA-74215 https://reactome.org/PathwayBrowser/#/R-CFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Canis familiaris 58017 R-CFA-9748951 https://reactome.org/PathwayBrowser/#/R-CFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Canis familiaris 58017 R-DDI-111215 https://reactome.org/PathwayBrowser/#/R-DDI-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Dictyostelium discoideum 58017 R-DDI-197186 https://reactome.org/PathwayBrowser/#/R-DDI-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Dictyostelium discoideum 58017 R-DDI-197268 https://reactome.org/PathwayBrowser/#/R-DDI-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Dictyostelium discoideum 58017 R-DDI-73567 https://reactome.org/PathwayBrowser/#/R-DDI-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Dictyostelium discoideum 58017 R-DDI-73580 https://reactome.org/PathwayBrowser/#/R-DDI-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Dictyostelium discoideum 58017 R-DDI-74215 https://reactome.org/PathwayBrowser/#/R-DDI-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Dictyostelium discoideum 58017 R-DDI-9748951 https://reactome.org/PathwayBrowser/#/R-DDI-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Dictyostelium discoideum 58017 R-DME-111289 https://reactome.org/PathwayBrowser/#/R-DME-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Drosophila melanogaster 58017 R-DME-197186 https://reactome.org/PathwayBrowser/#/R-DME-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Drosophila melanogaster 58017 R-DME-73567 https://reactome.org/PathwayBrowser/#/R-DME-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Drosophila melanogaster 58017 R-DME-73815 https://reactome.org/PathwayBrowser/#/R-DME-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Drosophila melanogaster 58017 R-DME-74213 https://reactome.org/PathwayBrowser/#/R-DME-74213 APRT catalyzes the conversion of adenine to AMP IEA Drosophila melanogaster 58017 R-DRE-111215 https://reactome.org/PathwayBrowser/#/R-DRE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Danio rerio 58017 R-DRE-111289 https://reactome.org/PathwayBrowser/#/R-DRE-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Danio rerio 58017 R-DRE-197186 https://reactome.org/PathwayBrowser/#/R-DRE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Danio rerio 58017 R-DRE-73580 https://reactome.org/PathwayBrowser/#/R-DRE-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Danio rerio 58017 R-DRE-73815 https://reactome.org/PathwayBrowser/#/R-DRE-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Danio rerio 58017 R-DRE-74213 https://reactome.org/PathwayBrowser/#/R-DRE-74213 APRT catalyzes the conversion of adenine to AMP IEA Danio rerio 58017 R-DRE-74215 https://reactome.org/PathwayBrowser/#/R-DRE-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Danio rerio 58017 R-DRE-9748951 https://reactome.org/PathwayBrowser/#/R-DRE-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Danio rerio 58017 R-GGA-111215 https://reactome.org/PathwayBrowser/#/R-GGA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Gallus gallus 58017 R-GGA-111289 https://reactome.org/PathwayBrowser/#/R-GGA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Gallus gallus 58017 R-GGA-197186 https://reactome.org/PathwayBrowser/#/R-GGA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Gallus gallus 58017 R-GGA-197250 https://reactome.org/PathwayBrowser/#/R-GGA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Gallus gallus 58017 R-GGA-197268 https://reactome.org/PathwayBrowser/#/R-GGA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Gallus gallus 58017 R-GGA-419152 https://reactome.org/PathwayBrowser/#/R-GGA-419152 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate TAS Gallus gallus 58017 R-GGA-419462 https://reactome.org/PathwayBrowser/#/R-GGA-419462 orotate + 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) <=> orotidine 5'-monophosphate (OMP) + pyrophosphate IEA Gallus gallus 58017 R-GGA-420906 https://reactome.org/PathwayBrowser/#/R-GGA-420906 Formation of PPAT tetramers TAS Gallus gallus 58017 R-GGA-420911 https://reactome.org/PathwayBrowser/#/R-GGA-420911 Formation of PPAT dimers IEA Gallus gallus 58017 R-GGA-73567 https://reactome.org/PathwayBrowser/#/R-GGA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Gallus gallus 58017 R-GGA-73580 https://reactome.org/PathwayBrowser/#/R-GGA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Gallus gallus 58017 R-GGA-73815 https://reactome.org/PathwayBrowser/#/R-GGA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Gallus gallus 58017 R-GGA-74213 https://reactome.org/PathwayBrowser/#/R-GGA-74213 APRT catalyzes the conversion of adenine to AMP IEA Gallus gallus 58017 R-GGA-74215 https://reactome.org/PathwayBrowser/#/R-GGA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Gallus gallus 58017 R-GGA-9748951 https://reactome.org/PathwayBrowser/#/R-GGA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Gallus gallus 58017 R-HSA-111215 https://reactome.org/PathwayBrowser/#/R-HSA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate TAS Homo sapiens 58017 R-HSA-111289 https://reactome.org/PathwayBrowser/#/R-HSA-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer TAS Homo sapiens 58017 R-HSA-197186 https://reactome.org/PathwayBrowser/#/R-HSA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN TAS Homo sapiens 58017 R-HSA-197250 https://reactome.org/PathwayBrowser/#/R-HSA-197250 NAMPT transfers PRIB to NAM to form NAMN TAS Homo sapiens 58017 R-HSA-197268 https://reactome.org/PathwayBrowser/#/R-HSA-197268 QPRT transfers PRIB to QUIN to form NAMN TAS Homo sapiens 58017 R-HSA-73567 https://reactome.org/PathwayBrowser/#/R-HSA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP TAS Homo sapiens 58017 R-HSA-73580 https://reactome.org/PathwayBrowser/#/R-HSA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate TAS Homo sapiens 58017 R-HSA-73815 https://reactome.org/PathwayBrowser/#/R-HSA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate TAS Homo sapiens 58017 R-HSA-74213 https://reactome.org/PathwayBrowser/#/R-HSA-74213 APRT catalyzes the conversion of adenine to AMP TAS Homo sapiens 58017 R-HSA-74215 https://reactome.org/PathwayBrowser/#/R-HSA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 58017 R-HSA-9734193 https://reactome.org/PathwayBrowser/#/R-HSA-9734193 Defective APRT does not convert adenine to AMP TAS Homo sapiens 58017 R-HSA-9734274 https://reactome.org/PathwayBrowser/#/R-HSA-9734274 Defective HPRT1 does not convert guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 58017 R-HSA-9748951 https://reactome.org/PathwayBrowser/#/R-HSA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP TAS Homo sapiens 58017 R-MMU-111215 https://reactome.org/PathwayBrowser/#/R-MMU-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Mus musculus 58017 R-MMU-111289 https://reactome.org/PathwayBrowser/#/R-MMU-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Mus musculus 58017 R-MMU-197186 https://reactome.org/PathwayBrowser/#/R-MMU-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Mus musculus 58017 R-MMU-197250 https://reactome.org/PathwayBrowser/#/R-MMU-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Mus musculus 58017 R-MMU-197268 https://reactome.org/PathwayBrowser/#/R-MMU-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Mus musculus 58017 R-MMU-73567 https://reactome.org/PathwayBrowser/#/R-MMU-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Mus musculus 58017 R-MMU-73580 https://reactome.org/PathwayBrowser/#/R-MMU-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Mus musculus 58017 R-MMU-73815 https://reactome.org/PathwayBrowser/#/R-MMU-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Mus musculus 58017 R-MMU-74213 https://reactome.org/PathwayBrowser/#/R-MMU-74213 APRT catalyzes the conversion of adenine to AMP IEA Mus musculus 58017 R-MMU-74215 https://reactome.org/PathwayBrowser/#/R-MMU-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Mus musculus 58017 R-MMU-9748951 https://reactome.org/PathwayBrowser/#/R-MMU-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Mus musculus 58017 R-PFA-111215 https://reactome.org/PathwayBrowser/#/R-PFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Plasmodium falciparum 58017 R-PFA-197186 https://reactome.org/PathwayBrowser/#/R-PFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Plasmodium falciparum 58017 R-PFA-73580 https://reactome.org/PathwayBrowser/#/R-PFA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Plasmodium falciparum 58017 R-PFA-74215 https://reactome.org/PathwayBrowser/#/R-PFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Plasmodium falciparum 58017 R-PFA-9748951 https://reactome.org/PathwayBrowser/#/R-PFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Plasmodium falciparum 58017 R-RNO-111215 https://reactome.org/PathwayBrowser/#/R-RNO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Rattus norvegicus 58017 R-RNO-111289 https://reactome.org/PathwayBrowser/#/R-RNO-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Rattus norvegicus 58017 R-RNO-197186 https://reactome.org/PathwayBrowser/#/R-RNO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Rattus norvegicus 58017 R-RNO-197250 https://reactome.org/PathwayBrowser/#/R-RNO-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Rattus norvegicus 58017 R-RNO-197268 https://reactome.org/PathwayBrowser/#/R-RNO-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Rattus norvegicus 58017 R-RNO-73567 https://reactome.org/PathwayBrowser/#/R-RNO-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Rattus norvegicus 58017 R-RNO-73580 https://reactome.org/PathwayBrowser/#/R-RNO-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Rattus norvegicus 58017 R-RNO-73815 https://reactome.org/PathwayBrowser/#/R-RNO-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Rattus norvegicus 58017 R-RNO-74213 https://reactome.org/PathwayBrowser/#/R-RNO-74213 APRT catalyzes the conversion of adenine to AMP IEA Rattus norvegicus 58017 R-RNO-74215 https://reactome.org/PathwayBrowser/#/R-RNO-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Rattus norvegicus 58017 R-RNO-9748951 https://reactome.org/PathwayBrowser/#/R-RNO-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Rattus norvegicus 58017 R-SCE-111215 https://reactome.org/PathwayBrowser/#/R-SCE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Saccharomyces cerevisiae 58017 R-SCE-197186 https://reactome.org/PathwayBrowser/#/R-SCE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Saccharomyces cerevisiae 58017 R-SCE-197268 https://reactome.org/PathwayBrowser/#/R-SCE-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Saccharomyces cerevisiae 58017 R-SCE-73580 https://reactome.org/PathwayBrowser/#/R-SCE-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Saccharomyces cerevisiae 58017 R-SCE-74213 https://reactome.org/PathwayBrowser/#/R-SCE-74213 APRT catalyzes the conversion of adenine to AMP IEA Saccharomyces cerevisiae 58017 R-SPO-111215 https://reactome.org/PathwayBrowser/#/R-SPO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Schizosaccharomyces pombe 58017 R-SPO-197186 https://reactome.org/PathwayBrowser/#/R-SPO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Schizosaccharomyces pombe 58017 R-SPO-73580 https://reactome.org/PathwayBrowser/#/R-SPO-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Schizosaccharomyces pombe 58017 R-SPO-74213 https://reactome.org/PathwayBrowser/#/R-SPO-74213 APRT catalyzes the conversion of adenine to AMP IEA Schizosaccharomyces pombe 58017 R-SSC-111215 https://reactome.org/PathwayBrowser/#/R-SSC-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Sus scrofa 58017 R-SSC-111289 https://reactome.org/PathwayBrowser/#/R-SSC-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Sus scrofa 58017 R-SSC-197186 https://reactome.org/PathwayBrowser/#/R-SSC-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Sus scrofa 58017 R-SSC-197250 https://reactome.org/PathwayBrowser/#/R-SSC-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Sus scrofa 58017 R-SSC-197268 https://reactome.org/PathwayBrowser/#/R-SSC-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Sus scrofa 58017 R-SSC-73567 https://reactome.org/PathwayBrowser/#/R-SSC-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Sus scrofa 58017 R-SSC-73580 https://reactome.org/PathwayBrowser/#/R-SSC-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Sus scrofa 58017 R-SSC-73815 https://reactome.org/PathwayBrowser/#/R-SSC-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Sus scrofa 58017 R-SSC-74213 https://reactome.org/PathwayBrowser/#/R-SSC-74213 APRT catalyzes the conversion of adenine to AMP IEA Sus scrofa 58017 R-SSC-74215 https://reactome.org/PathwayBrowser/#/R-SSC-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Sus scrofa 58017 R-SSC-9748951 https://reactome.org/PathwayBrowser/#/R-SSC-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Sus scrofa 58017 R-XTR-111215 https://reactome.org/PathwayBrowser/#/R-XTR-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Xenopus tropicalis 58017 R-XTR-111289 https://reactome.org/PathwayBrowser/#/R-XTR-111289 Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Xenopus tropicalis 58017 R-XTR-197250 https://reactome.org/PathwayBrowser/#/R-XTR-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Xenopus tropicalis 58017 R-XTR-197268 https://reactome.org/PathwayBrowser/#/R-XTR-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Xenopus tropicalis 58017 R-XTR-73567 https://reactome.org/PathwayBrowser/#/R-XTR-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Xenopus tropicalis 58017 R-XTR-73580 https://reactome.org/PathwayBrowser/#/R-XTR-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Xenopus tropicalis 58017 R-XTR-73815 https://reactome.org/PathwayBrowser/#/R-XTR-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Xenopus tropicalis 58017 R-XTR-74213 https://reactome.org/PathwayBrowser/#/R-XTR-74213 APRT catalyzes the conversion of adenine to AMP IEA Xenopus tropicalis 58020 R-BTA-9014627 https://reactome.org/PathwayBrowser/#/R-BTA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Bos taurus 58020 R-BTA-9014641 https://reactome.org/PathwayBrowser/#/R-BTA-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Bos taurus 58020 R-CEL-9014641 https://reactome.org/PathwayBrowser/#/R-CEL-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Caenorhabditis elegans 58020 R-CFA-9014627 https://reactome.org/PathwayBrowser/#/R-CFA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Canis familiaris 58020 R-CFA-9014641 https://reactome.org/PathwayBrowser/#/R-CFA-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Canis familiaris 58020 R-DDI-9014627 https://reactome.org/PathwayBrowser/#/R-DDI-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Dictyostelium discoideum 58020 R-DDI-9014641 https://reactome.org/PathwayBrowser/#/R-DDI-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Dictyostelium discoideum 58020 R-DME-9014641 https://reactome.org/PathwayBrowser/#/R-DME-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Drosophila melanogaster 58020 R-DRE-9014641 https://reactome.org/PathwayBrowser/#/R-DRE-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Danio rerio 58020 R-GGA-9014627 https://reactome.org/PathwayBrowser/#/R-GGA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Gallus gallus 58020 R-GGA-9014641 https://reactome.org/PathwayBrowser/#/R-GGA-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Gallus gallus 58020 R-HSA-9014627 https://reactome.org/PathwayBrowser/#/R-HSA-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA TAS Homo sapiens 58020 R-HSA-9014641 https://reactome.org/PathwayBrowser/#/R-HSA-9014641 HRSP12 deaminates 2AA to 2OBUTA TAS Homo sapiens 58020 R-MMU-9014627 https://reactome.org/PathwayBrowser/#/R-MMU-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Mus musculus 58020 R-MMU-9014641 https://reactome.org/PathwayBrowser/#/R-MMU-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Mus musculus 58020 R-RNO-9014627 https://reactome.org/PathwayBrowser/#/R-RNO-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Rattus norvegicus 58020 R-RNO-9014641 https://reactome.org/PathwayBrowser/#/R-RNO-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Rattus norvegicus 58020 R-SCE-9014627 https://reactome.org/PathwayBrowser/#/R-SCE-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Saccharomyces cerevisiae 58020 R-SCE-9014641 https://reactome.org/PathwayBrowser/#/R-SCE-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Saccharomyces cerevisiae 58020 R-SPO-9014641 https://reactome.org/PathwayBrowser/#/R-SPO-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Schizosaccharomyces pombe 58020 R-SSC-9014627 https://reactome.org/PathwayBrowser/#/R-SSC-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Sus scrofa 58020 R-SSC-9014641 https://reactome.org/PathwayBrowser/#/R-SSC-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Sus scrofa 58020 R-XTR-9014627 https://reactome.org/PathwayBrowser/#/R-XTR-9014627 SDS dimers:PXLP dehydrate L-Thr to 2AA IEA Xenopus tropicalis 58020 R-XTR-9014641 https://reactome.org/PathwayBrowser/#/R-XTR-9014641 HRSP12 deaminates 2AA to 2OBUTA IEA Xenopus tropicalis 58029 R-BTA-6814153 https://reactome.org/PathwayBrowser/#/R-BTA-6814153 ADO oxidises 2AET to HTAU IEA Bos taurus 58029 R-BTA-8938300 https://reactome.org/PathwayBrowser/#/R-BTA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Bos taurus 58029 R-CEL-6814153 https://reactome.org/PathwayBrowser/#/R-CEL-6814153 ADO oxidises 2AET to HTAU IEA Caenorhabditis elegans 58029 R-CFA-6814153 https://reactome.org/PathwayBrowser/#/R-CFA-6814153 ADO oxidises 2AET to HTAU IEA Canis familiaris 58029 R-CFA-8938300 https://reactome.org/PathwayBrowser/#/R-CFA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Canis familiaris 58029 R-DDI-6814153 https://reactome.org/PathwayBrowser/#/R-DDI-6814153 ADO oxidises 2AET to HTAU IEA Dictyostelium discoideum 58029 R-DDI-8938300 https://reactome.org/PathwayBrowser/#/R-DDI-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Dictyostelium discoideum 58029 R-DME-6814153 https://reactome.org/PathwayBrowser/#/R-DME-6814153 ADO oxidises 2AET to HTAU IEA Drosophila melanogaster 58029 R-DRE-6814153 https://reactome.org/PathwayBrowser/#/R-DRE-6814153 ADO oxidises 2AET to HTAU IEA Danio rerio 58029 R-GGA-8938300 https://reactome.org/PathwayBrowser/#/R-GGA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Gallus gallus 58029 R-HSA-6814153 https://reactome.org/PathwayBrowser/#/R-HSA-6814153 ADO oxidises 2AET to HTAU TAS Homo sapiens 58029 R-HSA-8938300 https://reactome.org/PathwayBrowser/#/R-HSA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET TAS Homo sapiens 58029 R-MMU-6814153 https://reactome.org/PathwayBrowser/#/R-MMU-6814153 ADO oxidises 2AET to HTAU IEA Mus musculus 58029 R-MMU-8938300 https://reactome.org/PathwayBrowser/#/R-MMU-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Mus musculus 58029 R-RNO-6814153 https://reactome.org/PathwayBrowser/#/R-RNO-6814153 ADO oxidises 2AET to HTAU IEA Rattus norvegicus 58029 R-RNO-8938300 https://reactome.org/PathwayBrowser/#/R-RNO-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Rattus norvegicus 58029 R-SSC-6814153 https://reactome.org/PathwayBrowser/#/R-SSC-6814153 ADO oxidises 2AET to HTAU IEA Sus scrofa 58029 R-SSC-8938300 https://reactome.org/PathwayBrowser/#/R-SSC-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Sus scrofa 58029 R-XTR-6814153 https://reactome.org/PathwayBrowser/#/R-XTR-6814153 ADO oxidises 2AET to HTAU IEA Xenopus tropicalis 58029 R-XTR-8938300 https://reactome.org/PathwayBrowser/#/R-XTR-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Xenopus tropicalis 58043 R-BTA-8850854 https://reactome.org/PathwayBrowser/#/R-BTA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Bos taurus 58043 R-BTA-8851129 https://reactome.org/PathwayBrowser/#/R-BTA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Bos taurus 58043 R-CFA-8850854 https://reactome.org/PathwayBrowser/#/R-CFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58043 R-CFA-8851129 https://reactome.org/PathwayBrowser/#/R-CFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58043 R-GGA-8850854 https://reactome.org/PathwayBrowser/#/R-GGA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58043 R-GGA-8851129 https://reactome.org/PathwayBrowser/#/R-GGA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58043 R-HSA-8850854 https://reactome.org/PathwayBrowser/#/R-HSA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58043 R-HSA-8851129 https://reactome.org/PathwayBrowser/#/R-HSA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58043 R-MMU-8850854 https://reactome.org/PathwayBrowser/#/R-MMU-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Mus musculus 58043 R-MMU-8851129 https://reactome.org/PathwayBrowser/#/R-MMU-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Mus musculus 58043 R-PFA-8850854 https://reactome.org/PathwayBrowser/#/R-PFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58043 R-PFA-8851129 https://reactome.org/PathwayBrowser/#/R-PFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58043 R-RNO-8850854 https://reactome.org/PathwayBrowser/#/R-RNO-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58043 R-RNO-8851129 https://reactome.org/PathwayBrowser/#/R-RNO-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58043 R-SSC-8850854 https://reactome.org/PathwayBrowser/#/R-SSC-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58043 R-SSC-8851129 https://reactome.org/PathwayBrowser/#/R-SSC-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58043 R-XTR-8850854 https://reactome.org/PathwayBrowser/#/R-XTR-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58043 R-XTR-8851129 https://reactome.org/PathwayBrowser/#/R-XTR-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58044 R-BTA-9749971 https://reactome.org/PathwayBrowser/#/R-BTA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Bos taurus 58044 R-BTA-9750016 https://reactome.org/PathwayBrowser/#/R-BTA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Bos taurus 58044 R-BTA-9750656 https://reactome.org/PathwayBrowser/#/R-BTA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Bos taurus 58044 R-CEL-9750016 https://reactome.org/PathwayBrowser/#/R-CEL-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Caenorhabditis elegans 58044 R-CEL-9750656 https://reactome.org/PathwayBrowser/#/R-CEL-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Caenorhabditis elegans 58044 R-CFA-9749971 https://reactome.org/PathwayBrowser/#/R-CFA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Canis familiaris 58044 R-CFA-9750016 https://reactome.org/PathwayBrowser/#/R-CFA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Canis familiaris 58044 R-CFA-9750656 https://reactome.org/PathwayBrowser/#/R-CFA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Canis familiaris 58044 R-DDI-9750016 https://reactome.org/PathwayBrowser/#/R-DDI-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Dictyostelium discoideum 58044 R-DDI-9750656 https://reactome.org/PathwayBrowser/#/R-DDI-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Dictyostelium discoideum 58044 R-DME-9750016 https://reactome.org/PathwayBrowser/#/R-DME-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Drosophila melanogaster 58044 R-DME-9750656 https://reactome.org/PathwayBrowser/#/R-DME-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Drosophila melanogaster 58044 R-DRE-9749971 https://reactome.org/PathwayBrowser/#/R-DRE-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Danio rerio 58044 R-DRE-9750016 https://reactome.org/PathwayBrowser/#/R-DRE-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Danio rerio 58044 R-DRE-9750656 https://reactome.org/PathwayBrowser/#/R-DRE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Danio rerio 58044 R-GGA-9749971 https://reactome.org/PathwayBrowser/#/R-GGA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Gallus gallus 58044 R-GGA-9750016 https://reactome.org/PathwayBrowser/#/R-GGA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Gallus gallus 58044 R-GGA-9750656 https://reactome.org/PathwayBrowser/#/R-GGA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Gallus gallus 58044 R-HSA-9749971 https://reactome.org/PathwayBrowser/#/R-HSA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA TAS Homo sapiens 58044 R-HSA-9750016 https://reactome.org/PathwayBrowser/#/R-HSA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA TAS Homo sapiens 58044 R-HSA-9750656 https://reactome.org/PathwayBrowser/#/R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells TAS Homo sapiens 58044 R-HSA-9757456 https://reactome.org/PathwayBrowser/#/R-HSA-9757456 2,5-DHBA translocates from ER lumen to mitochondrial matrix TAS Homo sapiens 58044 R-HSA-9757459 https://reactome.org/PathwayBrowser/#/R-HSA-9757459 ST metabolites diffuse out of ER lumen TAS Homo sapiens 58044 R-MMU-9749971 https://reactome.org/PathwayBrowser/#/R-MMU-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Mus musculus 58044 R-MMU-9750016 https://reactome.org/PathwayBrowser/#/R-MMU-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Mus musculus 58044 R-MMU-9750656 https://reactome.org/PathwayBrowser/#/R-MMU-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Mus musculus 58044 R-RNO-9749971 https://reactome.org/PathwayBrowser/#/R-RNO-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Rattus norvegicus 58044 R-RNO-9750016 https://reactome.org/PathwayBrowser/#/R-RNO-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Rattus norvegicus 58044 R-RNO-9750656 https://reactome.org/PathwayBrowser/#/R-RNO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Rattus norvegicus 58044 R-SCE-9750656 https://reactome.org/PathwayBrowser/#/R-SCE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Saccharomyces cerevisiae 58044 R-SPO-9750656 https://reactome.org/PathwayBrowser/#/R-SPO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Schizosaccharomyces pombe 58044 R-SSC-9749971 https://reactome.org/PathwayBrowser/#/R-SSC-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Sus scrofa 58044 R-SSC-9750016 https://reactome.org/PathwayBrowser/#/R-SSC-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Sus scrofa 58044 R-SSC-9750656 https://reactome.org/PathwayBrowser/#/R-SSC-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Sus scrofa 58044 R-XTR-9749971 https://reactome.org/PathwayBrowser/#/R-XTR-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Xenopus tropicalis 58044 R-XTR-9750016 https://reactome.org/PathwayBrowser/#/R-XTR-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Xenopus tropicalis 58044 R-XTR-9750656 https://reactome.org/PathwayBrowser/#/R-XTR-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Xenopus tropicalis 58045 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 58045 R-BTA-352103 https://reactome.org/PathwayBrowser/#/R-BTA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Bos taurus 58045 R-BTA-352107 https://reactome.org/PathwayBrowser/#/R-BTA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Bos taurus 58045 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 58045 R-BTA-352232 https://reactome.org/PathwayBrowser/#/R-BTA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Bos taurus 58045 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 58045 R-BTA-375487 https://reactome.org/PathwayBrowser/#/R-BTA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Bos taurus 58045 R-BTA-508179 https://reactome.org/PathwayBrowser/#/R-BTA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Bos taurus 58045 R-BTA-508189 https://reactome.org/PathwayBrowser/#/R-BTA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Bos taurus 58045 R-BTA-70723 https://reactome.org/PathwayBrowser/#/R-BTA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Bos taurus 58045 R-BTA-70724 https://reactome.org/PathwayBrowser/#/R-BTA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Bos taurus 58045 R-CEL-375487 https://reactome.org/PathwayBrowser/#/R-CEL-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 58045 R-CEL-508179 https://reactome.org/PathwayBrowser/#/R-CEL-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Caenorhabditis elegans 58045 R-CEL-508189 https://reactome.org/PathwayBrowser/#/R-CEL-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Caenorhabditis elegans 58045 R-CEL-70723 https://reactome.org/PathwayBrowser/#/R-CEL-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Caenorhabditis elegans 58045 R-CEL-70724 https://reactome.org/PathwayBrowser/#/R-CEL-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Caenorhabditis elegans 58045 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 58045 R-CFA-352103 https://reactome.org/PathwayBrowser/#/R-CFA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Canis familiaris 58045 R-CFA-352107 https://reactome.org/PathwayBrowser/#/R-CFA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Canis familiaris 58045 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 58045 R-CFA-352232 https://reactome.org/PathwayBrowser/#/R-CFA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Canis familiaris 58045 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 58045 R-CFA-375487 https://reactome.org/PathwayBrowser/#/R-CFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Canis familiaris 58045 R-CFA-508179 https://reactome.org/PathwayBrowser/#/R-CFA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Canis familiaris 58045 R-CFA-508189 https://reactome.org/PathwayBrowser/#/R-CFA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Canis familiaris 58045 R-CFA-70723 https://reactome.org/PathwayBrowser/#/R-CFA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Canis familiaris 58045 R-CFA-70724 https://reactome.org/PathwayBrowser/#/R-CFA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Canis familiaris 58045 R-DDI-508179 https://reactome.org/PathwayBrowser/#/R-DDI-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Dictyostelium discoideum 58045 R-DDI-508189 https://reactome.org/PathwayBrowser/#/R-DDI-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Dictyostelium discoideum 58045 R-DDI-70723 https://reactome.org/PathwayBrowser/#/R-DDI-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Dictyostelium discoideum 58045 R-DDI-70724 https://reactome.org/PathwayBrowser/#/R-DDI-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Dictyostelium discoideum 58045 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 58045 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 58045 R-DME-352232 https://reactome.org/PathwayBrowser/#/R-DME-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Drosophila melanogaster 58045 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 58045 R-DME-375487 https://reactome.org/PathwayBrowser/#/R-DME-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Drosophila melanogaster 58045 R-DME-508179 https://reactome.org/PathwayBrowser/#/R-DME-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Drosophila melanogaster 58045 R-DME-508189 https://reactome.org/PathwayBrowser/#/R-DME-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Drosophila melanogaster 58045 R-DME-70723 https://reactome.org/PathwayBrowser/#/R-DME-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Drosophila melanogaster 58045 R-DME-70724 https://reactome.org/PathwayBrowser/#/R-DME-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Drosophila melanogaster 58045 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 58045 R-DRE-352103 https://reactome.org/PathwayBrowser/#/R-DRE-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Danio rerio 58045 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 58045 R-DRE-508179 https://reactome.org/PathwayBrowser/#/R-DRE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Danio rerio 58045 R-DRE-508189 https://reactome.org/PathwayBrowser/#/R-DRE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Danio rerio 58045 R-DRE-70723 https://reactome.org/PathwayBrowser/#/R-DRE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Danio rerio 58045 R-DRE-70724 https://reactome.org/PathwayBrowser/#/R-DRE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Danio rerio 58045 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 58045 R-GGA-352107 https://reactome.org/PathwayBrowser/#/R-GGA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Gallus gallus 58045 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 58045 R-GGA-375487 https://reactome.org/PathwayBrowser/#/R-GGA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Gallus gallus 58045 R-GGA-508189 https://reactome.org/PathwayBrowser/#/R-GGA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Gallus gallus 58045 R-GGA-70723 https://reactome.org/PathwayBrowser/#/R-GGA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Gallus gallus 58045 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 58045 R-HSA-352103 https://reactome.org/PathwayBrowser/#/R-HSA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids TAS Homo sapiens 58045 R-HSA-352107 https://reactome.org/PathwayBrowser/#/R-HSA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids TAS Homo sapiens 58045 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 58045 R-HSA-352232 https://reactome.org/PathwayBrowser/#/R-HSA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol TAS Homo sapiens 58045 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 58045 R-HSA-375487 https://reactome.org/PathwayBrowser/#/R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 58045 R-HSA-379893 https://reactome.org/PathwayBrowser/#/R-HSA-379893 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 58045 R-HSA-380176 https://reactome.org/PathwayBrowser/#/R-HSA-380176 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate TAS Homo sapiens 58045 R-HSA-508179 https://reactome.org/PathwayBrowser/#/R-HSA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] TAS Homo sapiens 58045 R-HSA-508189 https://reactome.org/PathwayBrowser/#/R-HSA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] TAS Homo sapiens 58045 R-HSA-5659674 https://reactome.org/PathwayBrowser/#/R-HSA-5659674 Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol TAS Homo sapiens 58045 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 58045 R-HSA-70723 https://reactome.org/PathwayBrowser/#/R-HSA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] TAS Homo sapiens 58045 R-HSA-70724 https://reactome.org/PathwayBrowser/#/R-HSA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] TAS Homo sapiens 58045 R-HSA-9672770 https://reactome.org/PathwayBrowser/#/R-HSA-9672770 SLC25A44 transports Leu, Ile and Val from cytosol to mitochondrial matrix IEA Homo sapiens 58045 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 58045 R-MMU-352103 https://reactome.org/PathwayBrowser/#/R-MMU-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Mus musculus 58045 R-MMU-352107 https://reactome.org/PathwayBrowser/#/R-MMU-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Mus musculus 58045 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 58045 R-MMU-352232 https://reactome.org/PathwayBrowser/#/R-MMU-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Mus musculus 58045 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 58045 R-MMU-375487 https://reactome.org/PathwayBrowser/#/R-MMU-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Mus musculus 58045 R-MMU-508179 https://reactome.org/PathwayBrowser/#/R-MMU-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Mus musculus 58045 R-MMU-508189 https://reactome.org/PathwayBrowser/#/R-MMU-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Mus musculus 58045 R-MMU-70723 https://reactome.org/PathwayBrowser/#/R-MMU-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Mus musculus 58045 R-MMU-70724 https://reactome.org/PathwayBrowser/#/R-MMU-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Mus musculus 58045 R-MMU-9673827 https://reactome.org/PathwayBrowser/#/R-MMU-9673827 Slc25a44 transports Leu, Ile and Val from cytosol to mitochondrial matrix TAS Mus musculus 58045 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 58045 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 58045 R-PFA-375487 https://reactome.org/PathwayBrowser/#/R-PFA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Plasmodium falciparum 58045 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 58045 R-RNO-352103 https://reactome.org/PathwayBrowser/#/R-RNO-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Rattus norvegicus 58045 R-RNO-352107 https://reactome.org/PathwayBrowser/#/R-RNO-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Rattus norvegicus 58045 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 58045 R-RNO-352232 https://reactome.org/PathwayBrowser/#/R-RNO-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Rattus norvegicus 58045 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 58045 R-RNO-375487 https://reactome.org/PathwayBrowser/#/R-RNO-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Rattus norvegicus 58045 R-RNO-508179 https://reactome.org/PathwayBrowser/#/R-RNO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Rattus norvegicus 58045 R-RNO-508189 https://reactome.org/PathwayBrowser/#/R-RNO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Rattus norvegicus 58045 R-RNO-70723 https://reactome.org/PathwayBrowser/#/R-RNO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Rattus norvegicus 58045 R-RNO-70724 https://reactome.org/PathwayBrowser/#/R-RNO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Rattus norvegicus 58045 R-SCE-508179 https://reactome.org/PathwayBrowser/#/R-SCE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Saccharomyces cerevisiae 58045 R-SCE-508189 https://reactome.org/PathwayBrowser/#/R-SCE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Saccharomyces cerevisiae 58045 R-SCE-70723 https://reactome.org/PathwayBrowser/#/R-SCE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Saccharomyces cerevisiae 58045 R-SCE-70724 https://reactome.org/PathwayBrowser/#/R-SCE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Saccharomyces cerevisiae 58045 R-SPO-508179 https://reactome.org/PathwayBrowser/#/R-SPO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Schizosaccharomyces pombe 58045 R-SPO-508189 https://reactome.org/PathwayBrowser/#/R-SPO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Schizosaccharomyces pombe 58045 R-SPO-70723 https://reactome.org/PathwayBrowser/#/R-SPO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Schizosaccharomyces pombe 58045 R-SPO-70724 https://reactome.org/PathwayBrowser/#/R-SPO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Schizosaccharomyces pombe 58045 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 58045 R-SSC-352103 https://reactome.org/PathwayBrowser/#/R-SSC-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Sus scrofa 58045 R-SSC-352107 https://reactome.org/PathwayBrowser/#/R-SSC-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Sus scrofa 58045 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 58045 R-SSC-352232 https://reactome.org/PathwayBrowser/#/R-SSC-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Sus scrofa 58045 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 58045 R-SSC-375487 https://reactome.org/PathwayBrowser/#/R-SSC-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Sus scrofa 58045 R-SSC-508179 https://reactome.org/PathwayBrowser/#/R-SSC-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Sus scrofa 58045 R-SSC-508189 https://reactome.org/PathwayBrowser/#/R-SSC-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Sus scrofa 58045 R-SSC-70723 https://reactome.org/PathwayBrowser/#/R-SSC-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Sus scrofa 58045 R-SSC-70724 https://reactome.org/PathwayBrowser/#/R-SSC-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Sus scrofa 58045 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 58045 R-XTR-352103 https://reactome.org/PathwayBrowser/#/R-XTR-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Xenopus tropicalis 58045 R-XTR-352107 https://reactome.org/PathwayBrowser/#/R-XTR-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Xenopus tropicalis 58045 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 58045 R-XTR-352232 https://reactome.org/PathwayBrowser/#/R-XTR-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Xenopus tropicalis 58045 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 58045 R-XTR-375487 https://reactome.org/PathwayBrowser/#/R-XTR-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol IEA Xenopus tropicalis 58045 R-XTR-508179 https://reactome.org/PathwayBrowser/#/R-XTR-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Xenopus tropicalis 58045 R-XTR-508189 https://reactome.org/PathwayBrowser/#/R-XTR-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Xenopus tropicalis 58045 R-XTR-70723 https://reactome.org/PathwayBrowser/#/R-XTR-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Xenopus tropicalis 58045 R-XTR-70724 https://reactome.org/PathwayBrowser/#/R-XTR-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Xenopus tropicalis 58048 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 58048 R-BTA-352108 https://reactome.org/PathwayBrowser/#/R-BTA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Bos taurus 58048 R-BTA-352119 https://reactome.org/PathwayBrowser/#/R-BTA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Bos taurus 58048 R-BTA-352174 https://reactome.org/PathwayBrowser/#/R-BTA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Bos taurus 58048 R-BTA-352182 https://reactome.org/PathwayBrowser/#/R-BTA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Bos taurus 58048 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 58048 R-BTA-6797627 https://reactome.org/PathwayBrowser/#/R-BTA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Bos taurus 58048 R-BTA-70599 https://reactome.org/PathwayBrowser/#/R-BTA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Bos taurus 58048 R-CEL-6797627 https://reactome.org/PathwayBrowser/#/R-CEL-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Caenorhabditis elegans 58048 R-CEL-70599 https://reactome.org/PathwayBrowser/#/R-CEL-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Caenorhabditis elegans 58048 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 58048 R-CFA-352108 https://reactome.org/PathwayBrowser/#/R-CFA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Canis familiaris 58048 R-CFA-352119 https://reactome.org/PathwayBrowser/#/R-CFA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Canis familiaris 58048 R-CFA-352174 https://reactome.org/PathwayBrowser/#/R-CFA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Canis familiaris 58048 R-CFA-352182 https://reactome.org/PathwayBrowser/#/R-CFA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Canis familiaris 58048 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 58048 R-CFA-6797627 https://reactome.org/PathwayBrowser/#/R-CFA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Canis familiaris 58048 R-CFA-70599 https://reactome.org/PathwayBrowser/#/R-CFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Canis familiaris 58048 R-DDI-6797627 https://reactome.org/PathwayBrowser/#/R-DDI-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Dictyostelium discoideum 58048 R-DDI-70599 https://reactome.org/PathwayBrowser/#/R-DDI-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Dictyostelium discoideum 58048 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 58048 R-DME-352108 https://reactome.org/PathwayBrowser/#/R-DME-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 58048 R-DME-352119 https://reactome.org/PathwayBrowser/#/R-DME-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 58048 R-DME-352174 https://reactome.org/PathwayBrowser/#/R-DME-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Drosophila melanogaster 58048 R-DME-352182 https://reactome.org/PathwayBrowser/#/R-DME-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Drosophila melanogaster 58048 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 58048 R-DME-6797627 https://reactome.org/PathwayBrowser/#/R-DME-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Drosophila melanogaster 58048 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 58048 R-DRE-352108 https://reactome.org/PathwayBrowser/#/R-DRE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Danio rerio 58048 R-DRE-352182 https://reactome.org/PathwayBrowser/#/R-DRE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Danio rerio 58048 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 58048 R-GGA-352108 https://reactome.org/PathwayBrowser/#/R-GGA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Gallus gallus 58048 R-GGA-352119 https://reactome.org/PathwayBrowser/#/R-GGA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Gallus gallus 58048 R-GGA-352174 https://reactome.org/PathwayBrowser/#/R-GGA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Gallus gallus 58048 R-GGA-6797627 https://reactome.org/PathwayBrowser/#/R-GGA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Gallus gallus 58048 R-GGA-70599 https://reactome.org/PathwayBrowser/#/R-GGA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Gallus gallus 58048 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 58048 R-HSA-352108 https://reactome.org/PathwayBrowser/#/R-HSA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids TAS Homo sapiens 58048 R-HSA-352119 https://reactome.org/PathwayBrowser/#/R-HSA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids TAS Homo sapiens 58048 R-HSA-352174 https://reactome.org/PathwayBrowser/#/R-HSA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine TAS Homo sapiens 58048 R-HSA-352182 https://reactome.org/PathwayBrowser/#/R-HSA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine TAS Homo sapiens 58048 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 58048 R-HSA-379996 https://reactome.org/PathwayBrowser/#/R-HSA-379996 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate TAS Homo sapiens 58048 R-HSA-380227 https://reactome.org/PathwayBrowser/#/R-HSA-380227 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate IEA Homo sapiens 58048 R-HSA-5685345 https://reactome.org/PathwayBrowser/#/R-HSA-5685345 Formation of isoAsp TAS Homo sapiens 58048 R-HSA-6797627 https://reactome.org/PathwayBrowser/#/R-HSA-6797627 ASPG hydrolyses L-Asn to L-Asp TAS Homo sapiens 58048 R-HSA-70599 https://reactome.org/PathwayBrowser/#/R-HSA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] TAS Homo sapiens 58048 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 58048 R-MMU-352108 https://reactome.org/PathwayBrowser/#/R-MMU-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Mus musculus 58048 R-MMU-352119 https://reactome.org/PathwayBrowser/#/R-MMU-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Mus musculus 58048 R-MMU-352174 https://reactome.org/PathwayBrowser/#/R-MMU-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Mus musculus 58048 R-MMU-352182 https://reactome.org/PathwayBrowser/#/R-MMU-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Mus musculus 58048 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 58048 R-MMU-6797627 https://reactome.org/PathwayBrowser/#/R-MMU-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Mus musculus 58048 R-MMU-70599 https://reactome.org/PathwayBrowser/#/R-MMU-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Mus musculus 58048 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 58048 R-PFA-70599 https://reactome.org/PathwayBrowser/#/R-PFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Plasmodium falciparum 58048 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 58048 R-RNO-352108 https://reactome.org/PathwayBrowser/#/R-RNO-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Rattus norvegicus 58048 R-RNO-352119 https://reactome.org/PathwayBrowser/#/R-RNO-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Rattus norvegicus 58048 R-RNO-352174 https://reactome.org/PathwayBrowser/#/R-RNO-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Rattus norvegicus 58048 R-RNO-352182 https://reactome.org/PathwayBrowser/#/R-RNO-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Rattus norvegicus 58048 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 58048 R-RNO-6797627 https://reactome.org/PathwayBrowser/#/R-RNO-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Rattus norvegicus 58048 R-RNO-70599 https://reactome.org/PathwayBrowser/#/R-RNO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Rattus norvegicus 58048 R-SCE-352108 https://reactome.org/PathwayBrowser/#/R-SCE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 58048 R-SCE-352119 https://reactome.org/PathwayBrowser/#/R-SCE-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 58048 R-SCE-352174 https://reactome.org/PathwayBrowser/#/R-SCE-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Saccharomyces cerevisiae 58048 R-SCE-352182 https://reactome.org/PathwayBrowser/#/R-SCE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Saccharomyces cerevisiae 58048 R-SCE-70599 https://reactome.org/PathwayBrowser/#/R-SCE-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Saccharomyces cerevisiae 58048 R-SPO-70599 https://reactome.org/PathwayBrowser/#/R-SPO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Schizosaccharomyces pombe 58048 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 58048 R-SSC-352108 https://reactome.org/PathwayBrowser/#/R-SSC-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Sus scrofa 58048 R-SSC-352119 https://reactome.org/PathwayBrowser/#/R-SSC-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Sus scrofa 58048 R-SSC-352174 https://reactome.org/PathwayBrowser/#/R-SSC-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Sus scrofa 58048 R-SSC-352182 https://reactome.org/PathwayBrowser/#/R-SSC-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Sus scrofa 58048 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 58048 R-SSC-6797627 https://reactome.org/PathwayBrowser/#/R-SSC-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Sus scrofa 58048 R-SSC-70599 https://reactome.org/PathwayBrowser/#/R-SSC-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Sus scrofa 58048 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 58048 R-XTR-352108 https://reactome.org/PathwayBrowser/#/R-XTR-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 58048 R-XTR-352119 https://reactome.org/PathwayBrowser/#/R-XTR-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 58048 R-XTR-352174 https://reactome.org/PathwayBrowser/#/R-XTR-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Xenopus tropicalis 58048 R-XTR-352182 https://reactome.org/PathwayBrowser/#/R-XTR-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Xenopus tropicalis 58048 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 58048 R-XTR-6797627 https://reactome.org/PathwayBrowser/#/R-XTR-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Xenopus tropicalis 58048 R-XTR-70599 https://reactome.org/PathwayBrowser/#/R-XTR-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Xenopus tropicalis 58052 R-BTA-158546 https://reactome.org/PathwayBrowser/#/R-BTA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Bos taurus 58052 R-BTA-159179 https://reactome.org/PathwayBrowser/#/R-BTA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Bos taurus 58052 R-BTA-159194 https://reactome.org/PathwayBrowser/#/R-BTA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Bos taurus 58052 R-BTA-173597 https://reactome.org/PathwayBrowser/#/R-BTA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Bos taurus 58052 R-BTA-174368 https://reactome.org/PathwayBrowser/#/R-BTA-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Bos taurus 58052 R-BTA-174916 https://reactome.org/PathwayBrowser/#/R-BTA-174916 Formation of N-glucuronides IEA Bos taurus 58052 R-BTA-1889955 https://reactome.org/PathwayBrowser/#/R-BTA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Bos taurus 58052 R-BTA-1971491 https://reactome.org/PathwayBrowser/#/R-BTA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Bos taurus 58052 R-BTA-2022856 https://reactome.org/PathwayBrowser/#/R-BTA-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Bos taurus 58052 R-BTA-2076392 https://reactome.org/PathwayBrowser/#/R-BTA-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Bos taurus 58052 R-BTA-5617143 https://reactome.org/PathwayBrowser/#/R-BTA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Bos taurus 58052 R-BTA-9632034 https://reactome.org/PathwayBrowser/#/R-BTA-9632034 CHSY1 transfers GlcA to chondroitin IEA Bos taurus 58052 R-BTA-9638064 https://reactome.org/PathwayBrowser/#/R-BTA-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Bos taurus 58052 R-BTA-9638097 https://reactome.org/PathwayBrowser/#/R-BTA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Bos taurus 58052 R-BTA-9756134 https://reactome.org/PathwayBrowser/#/R-BTA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Bos taurus 58052 R-BTA-9756156 https://reactome.org/PathwayBrowser/#/R-BTA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Bos taurus 58052 R-BTA-9756183 https://reactome.org/PathwayBrowser/#/R-BTA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Bos taurus 58052 R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 58052 R-CEL-158546 https://reactome.org/PathwayBrowser/#/R-CEL-158546 UGTs glucuronate APAP to APAP-GlcA IEA Caenorhabditis elegans 58052 R-CEL-173597 https://reactome.org/PathwayBrowser/#/R-CEL-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Caenorhabditis elegans 58052 R-CEL-174368 https://reactome.org/PathwayBrowser/#/R-CEL-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Caenorhabditis elegans 58052 R-CEL-1889955 https://reactome.org/PathwayBrowser/#/R-CEL-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Caenorhabditis elegans 58052 R-CEL-9638064 https://reactome.org/PathwayBrowser/#/R-CEL-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Caenorhabditis elegans 58052 R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 58052 R-CFA-158546 https://reactome.org/PathwayBrowser/#/R-CFA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Canis familiaris 58052 R-CFA-173597 https://reactome.org/PathwayBrowser/#/R-CFA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Canis familiaris 58052 R-CFA-174368 https://reactome.org/PathwayBrowser/#/R-CFA-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Canis familiaris 58052 R-CFA-1889955 https://reactome.org/PathwayBrowser/#/R-CFA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Canis familiaris 58052 R-CFA-1971491 https://reactome.org/PathwayBrowser/#/R-CFA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Canis familiaris 58052 R-CFA-2022856 https://reactome.org/PathwayBrowser/#/R-CFA-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Canis familiaris 58052 R-CFA-2076392 https://reactome.org/PathwayBrowser/#/R-CFA-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Canis familiaris 58052 R-CFA-5617143 https://reactome.org/PathwayBrowser/#/R-CFA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Canis familiaris 58052 R-CFA-8941701 https://reactome.org/PathwayBrowser/#/R-CFA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Canis familiaris 58052 R-CFA-9632034 https://reactome.org/PathwayBrowser/#/R-CFA-9632034 CHSY1 transfers GlcA to chondroitin IEA Canis familiaris 58052 R-CFA-9638064 https://reactome.org/PathwayBrowser/#/R-CFA-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Canis familiaris 58052 R-CFA-9638097 https://reactome.org/PathwayBrowser/#/R-CFA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Canis familiaris 58052 R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 58052 R-DDI-158546 https://reactome.org/PathwayBrowser/#/R-DDI-158546 UGTs glucuronate APAP to APAP-GlcA IEA Dictyostelium discoideum 58052 R-DDI-159179 https://reactome.org/PathwayBrowser/#/R-DDI-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Dictyostelium discoideum 58052 R-DDI-159194 https://reactome.org/PathwayBrowser/#/R-DDI-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Dictyostelium discoideum 58052 R-DDI-174368 https://reactome.org/PathwayBrowser/#/R-DDI-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Dictyostelium discoideum 58052 R-DDI-174916 https://reactome.org/PathwayBrowser/#/R-DDI-174916 Formation of N-glucuronides IEA Dictyostelium discoideum 58052 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 58052 R-DDI-8941701 https://reactome.org/PathwayBrowser/#/R-DDI-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Dictyostelium discoideum 58052 R-DDI-9632038 https://reactome.org/PathwayBrowser/#/R-DDI-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Dictyostelium discoideum 58052 R-DDI-9632039 https://reactome.org/PathwayBrowser/#/R-DDI-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Dictyostelium discoideum 58052 R-DDI-9749977 https://reactome.org/PathwayBrowser/#/R-DDI-9749977 UGT1A6 glucuronates ST IEA Dictyostelium discoideum 58052 R-DDI-9756134 https://reactome.org/PathwayBrowser/#/R-DDI-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Dictyostelium discoideum 58052 R-DDI-9756156 https://reactome.org/PathwayBrowser/#/R-DDI-9756156 UGT1A3 lactonizes ATV to ATVL IEA Dictyostelium discoideum 58052 R-DDI-9756183 https://reactome.org/PathwayBrowser/#/R-DDI-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Dictyostelium discoideum 58052 R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 58052 R-DME-158546 https://reactome.org/PathwayBrowser/#/R-DME-158546 UGTs glucuronate APAP to APAP-GlcA IEA Drosophila melanogaster 58052 R-DME-173597 https://reactome.org/PathwayBrowser/#/R-DME-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Drosophila melanogaster 58052 R-DME-174368 https://reactome.org/PathwayBrowser/#/R-DME-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Drosophila melanogaster 58052 R-DME-1889955 https://reactome.org/PathwayBrowser/#/R-DME-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Drosophila melanogaster 58052 R-DME-1971491 https://reactome.org/PathwayBrowser/#/R-DME-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Drosophila melanogaster 58052 R-DME-2022856 https://reactome.org/PathwayBrowser/#/R-DME-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Drosophila melanogaster 58052 R-DME-2076392 https://reactome.org/PathwayBrowser/#/R-DME-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Drosophila melanogaster 58052 R-DME-9632034 https://reactome.org/PathwayBrowser/#/R-DME-9632034 CHSY1 transfers GlcA to chondroitin IEA Drosophila melanogaster 58052 R-DME-9638064 https://reactome.org/PathwayBrowser/#/R-DME-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Drosophila melanogaster 58052 R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 58052 R-DRE-158546 https://reactome.org/PathwayBrowser/#/R-DRE-158546 UGTs glucuronate APAP to APAP-GlcA IEA Danio rerio 58052 R-DRE-173597 https://reactome.org/PathwayBrowser/#/R-DRE-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Danio rerio 58052 R-DRE-174368 https://reactome.org/PathwayBrowser/#/R-DRE-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Danio rerio 58052 R-DRE-1889955 https://reactome.org/PathwayBrowser/#/R-DRE-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Danio rerio 58052 R-DRE-2022856 https://reactome.org/PathwayBrowser/#/R-DRE-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Danio rerio 58052 R-DRE-2076392 https://reactome.org/PathwayBrowser/#/R-DRE-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Danio rerio 58052 R-DRE-5617143 https://reactome.org/PathwayBrowser/#/R-DRE-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Danio rerio 58052 R-DRE-9632034 https://reactome.org/PathwayBrowser/#/R-DRE-9632034 CHSY1 transfers GlcA to chondroitin IEA Danio rerio 58052 R-DRE-9638097 https://reactome.org/PathwayBrowser/#/R-DRE-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Danio rerio 58052 R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 58052 R-GGA-158546 https://reactome.org/PathwayBrowser/#/R-GGA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Gallus gallus 58052 R-GGA-159179 https://reactome.org/PathwayBrowser/#/R-GGA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Gallus gallus 58052 R-GGA-159194 https://reactome.org/PathwayBrowser/#/R-GGA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Gallus gallus 58052 R-GGA-173597 https://reactome.org/PathwayBrowser/#/R-GGA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Gallus gallus 58052 R-GGA-174368 https://reactome.org/PathwayBrowser/#/R-GGA-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Gallus gallus 58052 R-GGA-174916 https://reactome.org/PathwayBrowser/#/R-GGA-174916 Formation of N-glucuronides IEA Gallus gallus 58052 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 58052 R-GGA-1889955 https://reactome.org/PathwayBrowser/#/R-GGA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Gallus gallus 58052 R-GGA-1971491 https://reactome.org/PathwayBrowser/#/R-GGA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Gallus gallus 58052 R-GGA-8941701 https://reactome.org/PathwayBrowser/#/R-GGA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Gallus gallus 58052 R-GGA-9632034 https://reactome.org/PathwayBrowser/#/R-GGA-9632034 CHSY1 transfers GlcA to chondroitin IEA Gallus gallus 58052 R-GGA-9632038 https://reactome.org/PathwayBrowser/#/R-GGA-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Gallus gallus 58052 R-GGA-9632039 https://reactome.org/PathwayBrowser/#/R-GGA-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Gallus gallus 58052 R-GGA-9749977 https://reactome.org/PathwayBrowser/#/R-GGA-9749977 UGT1A6 glucuronates ST IEA Gallus gallus 58052 R-GGA-9756134 https://reactome.org/PathwayBrowser/#/R-GGA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Gallus gallus 58052 R-GGA-9756156 https://reactome.org/PathwayBrowser/#/R-GGA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Gallus gallus 58052 R-GGA-9756183 https://reactome.org/PathwayBrowser/#/R-GGA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Gallus gallus 58052 R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 58052 R-HSA-158546 https://reactome.org/PathwayBrowser/#/R-HSA-158546 UGTs glucuronate APAP to APAP-GlcA TAS Homo sapiens 58052 R-HSA-159179 https://reactome.org/PathwayBrowser/#/R-HSA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG TAS Homo sapiens 58052 R-HSA-159194 https://reactome.org/PathwayBrowser/#/R-HSA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG TAS Homo sapiens 58052 R-HSA-173597 https://reactome.org/PathwayBrowser/#/R-HSA-173597 UDP-glucose is oxidised to UDP-glucuronate TAS Homo sapiens 58052 R-HSA-174368 https://reactome.org/PathwayBrowser/#/R-HSA-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen TAS Homo sapiens 58052 R-HSA-174916 https://reactome.org/PathwayBrowser/#/R-HSA-174916 Formation of N-glucuronides TAS Homo sapiens 58052 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 58052 R-HSA-1889955 https://reactome.org/PathwayBrowser/#/R-HSA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker TAS Homo sapiens 58052 R-HSA-1971491 https://reactome.org/PathwayBrowser/#/R-HSA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin TAS Homo sapiens 58052 R-HSA-2022856 https://reactome.org/PathwayBrowser/#/R-HSA-2022856 EXT1:EXT2 transfers GlcNAc to heparan TAS Homo sapiens 58052 R-HSA-2076392 https://reactome.org/PathwayBrowser/#/R-HSA-2076392 EXT1:EXT2 transfers GlcA to heparan TAS Homo sapiens 58052 R-HSA-2162099 https://reactome.org/PathwayBrowser/#/R-HSA-2162099 abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP TAS Homo sapiens 58052 R-HSA-3560802 https://reactome.org/PathwayBrowser/#/R-HSA-3560802 Defective B3GAT3 does not transfer GlcA to tetrasaccharide linker TAS Homo sapiens 58052 R-HSA-3595178 https://reactome.org/PathwayBrowser/#/R-HSA-3595178 Defective CHSY1 does not transfer GlcA to chondroitin TAS Homo sapiens 58052 R-HSA-3656257 https://reactome.org/PathwayBrowser/#/R-HSA-3656257 Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan TAS Homo sapiens 58052 R-HSA-3656267 https://reactome.org/PathwayBrowser/#/R-HSA-3656267 Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan TAS Homo sapiens 58052 R-HSA-5603297 https://reactome.org/PathwayBrowser/#/R-HSA-5603297 Defective SLC35D1 does not transport UDP-GlcA, UDPGlcNAc TAS Homo sapiens 58052 R-HSA-5604954 https://reactome.org/PathwayBrowser/#/R-HSA-5604954 Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BIL TAS Homo sapiens 58052 R-HSA-5604975 https://reactome.org/PathwayBrowser/#/R-HSA-5604975 Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BIL TAS Homo sapiens 58052 R-HSA-5617143 https://reactome.org/PathwayBrowser/#/R-HSA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA TAS Homo sapiens 58052 R-HSA-8941701 https://reactome.org/PathwayBrowser/#/R-HSA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN TAS Homo sapiens 58052 R-HSA-9036102 https://reactome.org/PathwayBrowser/#/R-HSA-9036102 Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BMG TAS Homo sapiens 58052 R-HSA-9036104 https://reactome.org/PathwayBrowser/#/R-HSA-9036104 Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BMG TAS Homo sapiens 58052 R-HSA-9036285 https://reactome.org/PathwayBrowser/#/R-HSA-9036285 Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan TAS Homo sapiens 58052 R-HSA-9036289 https://reactome.org/PathwayBrowser/#/R-HSA-9036289 Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan TAS Homo sapiens 58052 R-HSA-9632034 https://reactome.org/PathwayBrowser/#/R-HSA-9632034 CHSY1 transfers GlcA to chondroitin TAS Homo sapiens 58052 R-HSA-9632038 https://reactome.org/PathwayBrowser/#/R-HSA-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG TAS Homo sapiens 58052 R-HSA-9632039 https://reactome.org/PathwayBrowser/#/R-HSA-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG TAS Homo sapiens 58052 R-HSA-9638064 https://reactome.org/PathwayBrowser/#/R-HSA-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker TAS Homo sapiens 58052 R-HSA-9638097 https://reactome.org/PathwayBrowser/#/R-HSA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA TAS Homo sapiens 58052 R-HSA-9749977 https://reactome.org/PathwayBrowser/#/R-HSA-9749977 UGT1A6 glucuronates ST TAS Homo sapiens 58052 R-HSA-9756134 https://reactome.org/PathwayBrowser/#/R-HSA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL TAS Homo sapiens 58052 R-HSA-9756156 https://reactome.org/PathwayBrowser/#/R-HSA-9756156 UGT1A3 lactonizes ATV to ATVL TAS Homo sapiens 58052 R-HSA-9756183 https://reactome.org/PathwayBrowser/#/R-HSA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL TAS Homo sapiens 58052 R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 58052 R-MMU-158546 https://reactome.org/PathwayBrowser/#/R-MMU-158546 UGTs glucuronate APAP to APAP-GlcA IEA Mus musculus 58052 R-MMU-159179 https://reactome.org/PathwayBrowser/#/R-MMU-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Mus musculus 58052 R-MMU-159194 https://reactome.org/PathwayBrowser/#/R-MMU-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Mus musculus 58052 R-MMU-173597 https://reactome.org/PathwayBrowser/#/R-MMU-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Mus musculus 58052 R-MMU-174368 https://reactome.org/PathwayBrowser/#/R-MMU-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Mus musculus 58052 R-MMU-174916 https://reactome.org/PathwayBrowser/#/R-MMU-174916 Formation of N-glucuronides IEA Mus musculus 58052 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 58052 R-MMU-1889955 https://reactome.org/PathwayBrowser/#/R-MMU-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Mus musculus 58052 R-MMU-1971491 https://reactome.org/PathwayBrowser/#/R-MMU-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Mus musculus 58052 R-MMU-2022856 https://reactome.org/PathwayBrowser/#/R-MMU-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Mus musculus 58052 R-MMU-2076392 https://reactome.org/PathwayBrowser/#/R-MMU-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Mus musculus 58052 R-MMU-5617143 https://reactome.org/PathwayBrowser/#/R-MMU-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Mus musculus 58052 R-MMU-8941701 https://reactome.org/PathwayBrowser/#/R-MMU-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Mus musculus 58052 R-MMU-9632034 https://reactome.org/PathwayBrowser/#/R-MMU-9632034 CHSY1 transfers GlcA to chondroitin IEA Mus musculus 58052 R-MMU-9632038 https://reactome.org/PathwayBrowser/#/R-MMU-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Mus musculus 58052 R-MMU-9632039 https://reactome.org/PathwayBrowser/#/R-MMU-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Mus musculus 58052 R-MMU-9638064 https://reactome.org/PathwayBrowser/#/R-MMU-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Mus musculus 58052 R-MMU-9638097 https://reactome.org/PathwayBrowser/#/R-MMU-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Mus musculus 58052 R-MMU-9749977 https://reactome.org/PathwayBrowser/#/R-MMU-9749977 UGT1A6 glucuronates ST IEA Mus musculus 58052 R-MMU-9756134 https://reactome.org/PathwayBrowser/#/R-MMU-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Mus musculus 58052 R-MMU-9756156 https://reactome.org/PathwayBrowser/#/R-MMU-9756156 UGT1A3 lactonizes ATV to ATVL IEA Mus musculus 58052 R-MMU-9756183 https://reactome.org/PathwayBrowser/#/R-MMU-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Mus musculus 58052 R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 58052 R-RNO-158546 https://reactome.org/PathwayBrowser/#/R-RNO-158546 UGTs glucuronate APAP to APAP-GlcA IEA Rattus norvegicus 58052 R-RNO-159179 https://reactome.org/PathwayBrowser/#/R-RNO-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Rattus norvegicus 58052 R-RNO-159194 https://reactome.org/PathwayBrowser/#/R-RNO-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Rattus norvegicus 58052 R-RNO-173597 https://reactome.org/PathwayBrowser/#/R-RNO-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Rattus norvegicus 58052 R-RNO-174368 https://reactome.org/PathwayBrowser/#/R-RNO-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Rattus norvegicus 58052 R-RNO-174916 https://reactome.org/PathwayBrowser/#/R-RNO-174916 Formation of N-glucuronides IEA Rattus norvegicus 58052 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 58052 R-RNO-1889955 https://reactome.org/PathwayBrowser/#/R-RNO-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Rattus norvegicus 58052 R-RNO-1971491 https://reactome.org/PathwayBrowser/#/R-RNO-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Rattus norvegicus 58052 R-RNO-2022856 https://reactome.org/PathwayBrowser/#/R-RNO-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Rattus norvegicus 58052 R-RNO-2076392 https://reactome.org/PathwayBrowser/#/R-RNO-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Rattus norvegicus 58052 R-RNO-5617143 https://reactome.org/PathwayBrowser/#/R-RNO-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Rattus norvegicus 58052 R-RNO-8941701 https://reactome.org/PathwayBrowser/#/R-RNO-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Rattus norvegicus 58052 R-RNO-9632034 https://reactome.org/PathwayBrowser/#/R-RNO-9632034 CHSY1 transfers GlcA to chondroitin IEA Rattus norvegicus 58052 R-RNO-9632038 https://reactome.org/PathwayBrowser/#/R-RNO-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Rattus norvegicus 58052 R-RNO-9632039 https://reactome.org/PathwayBrowser/#/R-RNO-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Rattus norvegicus 58052 R-RNO-9638097 https://reactome.org/PathwayBrowser/#/R-RNO-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Rattus norvegicus 58052 R-RNO-9749977 https://reactome.org/PathwayBrowser/#/R-RNO-9749977 UGT1A6 glucuronates ST IEA Rattus norvegicus 58052 R-RNO-9756134 https://reactome.org/PathwayBrowser/#/R-RNO-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Rattus norvegicus 58052 R-RNO-9756156 https://reactome.org/PathwayBrowser/#/R-RNO-9756156 UGT1A3 lactonizes ATV to ATVL IEA Rattus norvegicus 58052 R-RNO-9756183 https://reactome.org/PathwayBrowser/#/R-RNO-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Rattus norvegicus 58052 R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 58052 R-SSC-158546 https://reactome.org/PathwayBrowser/#/R-SSC-158546 UGTs glucuronate APAP to APAP-GlcA IEA Sus scrofa 58052 R-SSC-159179 https://reactome.org/PathwayBrowser/#/R-SSC-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Sus scrofa 58052 R-SSC-159194 https://reactome.org/PathwayBrowser/#/R-SSC-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG IEA Sus scrofa 58052 R-SSC-173597 https://reactome.org/PathwayBrowser/#/R-SSC-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Sus scrofa 58052 R-SSC-174368 https://reactome.org/PathwayBrowser/#/R-SSC-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen IEA Sus scrofa 58052 R-SSC-174916 https://reactome.org/PathwayBrowser/#/R-SSC-174916 Formation of N-glucuronides IEA Sus scrofa 58052 R-SSC-1889955 https://reactome.org/PathwayBrowser/#/R-SSC-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Sus scrofa 58052 R-SSC-1971491 https://reactome.org/PathwayBrowser/#/R-SSC-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Sus scrofa 58052 R-SSC-2022856 https://reactome.org/PathwayBrowser/#/R-SSC-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Sus scrofa 58052 R-SSC-2076392 https://reactome.org/PathwayBrowser/#/R-SSC-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Sus scrofa 58052 R-SSC-5617143 https://reactome.org/PathwayBrowser/#/R-SSC-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Sus scrofa 58052 R-SSC-9632034 https://reactome.org/PathwayBrowser/#/R-SSC-9632034 CHSY1 transfers GlcA to chondroitin IEA Sus scrofa 58052 R-SSC-9638064 https://reactome.org/PathwayBrowser/#/R-SSC-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Sus scrofa 58052 R-SSC-9638097 https://reactome.org/PathwayBrowser/#/R-SSC-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Sus scrofa 58052 R-SSC-9756134 https://reactome.org/PathwayBrowser/#/R-SSC-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Sus scrofa 58052 R-SSC-9756156 https://reactome.org/PathwayBrowser/#/R-SSC-9756156 UGT1A3 lactonizes ATV to ATVL IEA Sus scrofa 58052 R-SSC-9756183 https://reactome.org/PathwayBrowser/#/R-SSC-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Sus scrofa 58052 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 58052 R-XTR-173597 https://reactome.org/PathwayBrowser/#/R-XTR-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Xenopus tropicalis 58052 R-XTR-1889955 https://reactome.org/PathwayBrowser/#/R-XTR-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Xenopus tropicalis 58052 R-XTR-1971491 https://reactome.org/PathwayBrowser/#/R-XTR-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Xenopus tropicalis 58052 R-XTR-5617143 https://reactome.org/PathwayBrowser/#/R-XTR-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Xenopus tropicalis 58052 R-XTR-9632034 https://reactome.org/PathwayBrowser/#/R-XTR-9632034 CHSY1 transfers GlcA to chondroitin IEA Xenopus tropicalis 58052 R-XTR-9638064 https://reactome.org/PathwayBrowser/#/R-XTR-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Xenopus tropicalis 58052 R-XTR-9638097 https://reactome.org/PathwayBrowser/#/R-XTR-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Xenopus tropicalis 58053 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 58053 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 58053 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 58053 R-BTA-111285 https://reactome.org/PathwayBrowser/#/R-BTA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Bos taurus 58053 R-BTA-111524 https://reactome.org/PathwayBrowser/#/R-BTA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Bos taurus 58053 R-BTA-2161187 https://reactome.org/PathwayBrowser/#/R-BTA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Bos taurus 58053 R-BTA-2162066 https://reactome.org/PathwayBrowser/#/R-BTA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Bos taurus 58053 R-BTA-2509816 https://reactome.org/PathwayBrowser/#/R-BTA-2509816 NUDT16 hydrolyses IDP to IMP IEA Bos taurus 58053 R-BTA-2509827 https://reactome.org/PathwayBrowser/#/R-BTA-2509827 ITPA hydrolyses ITP to IMP IEA Bos taurus 58053 R-BTA-514604 https://reactome.org/PathwayBrowser/#/R-BTA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Bos taurus 58053 R-BTA-73794 https://reactome.org/PathwayBrowser/#/R-BTA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Bos taurus 58053 R-BTA-73797 https://reactome.org/PathwayBrowser/#/R-BTA-73797 FAICAR => IMP + H2O IEA Bos taurus 58053 R-BTA-74215 https://reactome.org/PathwayBrowser/#/R-BTA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Bos taurus 58053 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 58053 R-BTA-76590 https://reactome.org/PathwayBrowser/#/R-BTA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Bos taurus 58053 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 58053 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 58053 R-BTA-9717206 https://reactome.org/PathwayBrowser/#/R-BTA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Bos taurus 58053 R-BTA-9754916 https://reactome.org/PathwayBrowser/#/R-BTA-9754916 NT5C2 tetramer phosphorylates RBV IEA Bos taurus 58053 R-CEL-111285 https://reactome.org/PathwayBrowser/#/R-CEL-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Caenorhabditis elegans 58053 R-CEL-111524 https://reactome.org/PathwayBrowser/#/R-CEL-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Caenorhabditis elegans 58053 R-CEL-2161187 https://reactome.org/PathwayBrowser/#/R-CEL-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Caenorhabditis elegans 58053 R-CEL-2162066 https://reactome.org/PathwayBrowser/#/R-CEL-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Caenorhabditis elegans 58053 R-CEL-2509827 https://reactome.org/PathwayBrowser/#/R-CEL-2509827 ITPA hydrolyses ITP to IMP IEA Caenorhabditis elegans 58053 R-CEL-514604 https://reactome.org/PathwayBrowser/#/R-CEL-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Caenorhabditis elegans 58053 R-CEL-73794 https://reactome.org/PathwayBrowser/#/R-CEL-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Caenorhabditis elegans 58053 R-CEL-73797 https://reactome.org/PathwayBrowser/#/R-CEL-73797 FAICAR => IMP + H2O IEA Caenorhabditis elegans 58053 R-CEL-74215 https://reactome.org/PathwayBrowser/#/R-CEL-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Caenorhabditis elegans 58053 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 58053 R-CEL-76590 https://reactome.org/PathwayBrowser/#/R-CEL-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Caenorhabditis elegans 58053 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58053 R-CEL-9754916 https://reactome.org/PathwayBrowser/#/R-CEL-9754916 NT5C2 tetramer phosphorylates RBV IEA Caenorhabditis elegans 58053 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 58053 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 58053 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 58053 R-CFA-111285 https://reactome.org/PathwayBrowser/#/R-CFA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Canis familiaris 58053 R-CFA-111524 https://reactome.org/PathwayBrowser/#/R-CFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Canis familiaris 58053 R-CFA-2161187 https://reactome.org/PathwayBrowser/#/R-CFA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Canis familiaris 58053 R-CFA-2162066 https://reactome.org/PathwayBrowser/#/R-CFA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Canis familiaris 58053 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 58053 R-CFA-2509816 https://reactome.org/PathwayBrowser/#/R-CFA-2509816 NUDT16 hydrolyses IDP to IMP IEA Canis familiaris 58053 R-CFA-2509827 https://reactome.org/PathwayBrowser/#/R-CFA-2509827 ITPA hydrolyses ITP to IMP IEA Canis familiaris 58053 R-CFA-514604 https://reactome.org/PathwayBrowser/#/R-CFA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Canis familiaris 58053 R-CFA-73794 https://reactome.org/PathwayBrowser/#/R-CFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Canis familiaris 58053 R-CFA-73797 https://reactome.org/PathwayBrowser/#/R-CFA-73797 FAICAR => IMP + H2O IEA Canis familiaris 58053 R-CFA-74215 https://reactome.org/PathwayBrowser/#/R-CFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Canis familiaris 58053 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 58053 R-CFA-76590 https://reactome.org/PathwayBrowser/#/R-CFA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Canis familiaris 58053 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58053 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58053 R-CFA-9717206 https://reactome.org/PathwayBrowser/#/R-CFA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Canis familiaris 58053 R-CFA-9754916 https://reactome.org/PathwayBrowser/#/R-CFA-9754916 NT5C2 tetramer phosphorylates RBV IEA Canis familiaris 58053 R-DDI-111524 https://reactome.org/PathwayBrowser/#/R-DDI-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Dictyostelium discoideum 58053 R-DDI-2162066 https://reactome.org/PathwayBrowser/#/R-DDI-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Dictyostelium discoideum 58053 R-DDI-2509827 https://reactome.org/PathwayBrowser/#/R-DDI-2509827 ITPA hydrolyses ITP to IMP IEA Dictyostelium discoideum 58053 R-DDI-73794 https://reactome.org/PathwayBrowser/#/R-DDI-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Dictyostelium discoideum 58053 R-DDI-73797 https://reactome.org/PathwayBrowser/#/R-DDI-73797 FAICAR => IMP + H2O IEA Dictyostelium discoideum 58053 R-DDI-74215 https://reactome.org/PathwayBrowser/#/R-DDI-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Dictyostelium discoideum 58053 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 58053 R-DDI-76590 https://reactome.org/PathwayBrowser/#/R-DDI-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Dictyostelium discoideum 58053 R-DDI-9754916 https://reactome.org/PathwayBrowser/#/R-DDI-9754916 NT5C2 tetramer phosphorylates RBV IEA Dictyostelium discoideum 58053 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 58053 R-DME-111285 https://reactome.org/PathwayBrowser/#/R-DME-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Drosophila melanogaster 58053 R-DME-111524 https://reactome.org/PathwayBrowser/#/R-DME-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Drosophila melanogaster 58053 R-DME-2161187 https://reactome.org/PathwayBrowser/#/R-DME-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Drosophila melanogaster 58053 R-DME-2162066 https://reactome.org/PathwayBrowser/#/R-DME-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Drosophila melanogaster 58053 R-DME-2509827 https://reactome.org/PathwayBrowser/#/R-DME-2509827 ITPA hydrolyses ITP to IMP IEA Drosophila melanogaster 58053 R-DME-73794 https://reactome.org/PathwayBrowser/#/R-DME-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Drosophila melanogaster 58053 R-DME-73797 https://reactome.org/PathwayBrowser/#/R-DME-73797 FAICAR => IMP + H2O IEA Drosophila melanogaster 58053 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 58053 R-DME-76590 https://reactome.org/PathwayBrowser/#/R-DME-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Drosophila melanogaster 58053 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 58053 R-DME-9754916 https://reactome.org/PathwayBrowser/#/R-DME-9754916 NT5C2 tetramer phosphorylates RBV IEA Drosophila melanogaster 58053 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 58053 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 58053 R-DRE-111285 https://reactome.org/PathwayBrowser/#/R-DRE-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Danio rerio 58053 R-DRE-111524 https://reactome.org/PathwayBrowser/#/R-DRE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Danio rerio 58053 R-DRE-2161187 https://reactome.org/PathwayBrowser/#/R-DRE-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Danio rerio 58053 R-DRE-2509816 https://reactome.org/PathwayBrowser/#/R-DRE-2509816 NUDT16 hydrolyses IDP to IMP IEA Danio rerio 58053 R-DRE-2509827 https://reactome.org/PathwayBrowser/#/R-DRE-2509827 ITPA hydrolyses ITP to IMP IEA Danio rerio 58053 R-DRE-514604 https://reactome.org/PathwayBrowser/#/R-DRE-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Danio rerio 58053 R-DRE-73794 https://reactome.org/PathwayBrowser/#/R-DRE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Danio rerio 58053 R-DRE-73797 https://reactome.org/PathwayBrowser/#/R-DRE-73797 FAICAR => IMP + H2O IEA Danio rerio 58053 R-DRE-74215 https://reactome.org/PathwayBrowser/#/R-DRE-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Danio rerio 58053 R-DRE-76590 https://reactome.org/PathwayBrowser/#/R-DRE-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Danio rerio 58053 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 58053 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 58053 R-DRE-9717206 https://reactome.org/PathwayBrowser/#/R-DRE-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Danio rerio 58053 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 58053 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 58053 R-GGA-111285 https://reactome.org/PathwayBrowser/#/R-GGA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Gallus gallus 58053 R-GGA-111524 https://reactome.org/PathwayBrowser/#/R-GGA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Gallus gallus 58053 R-GGA-2161187 https://reactome.org/PathwayBrowser/#/R-GGA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Gallus gallus 58053 R-GGA-2162066 https://reactome.org/PathwayBrowser/#/R-GGA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Gallus gallus 58053 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 58053 R-GGA-2509827 https://reactome.org/PathwayBrowser/#/R-GGA-2509827 ITPA hydrolyses ITP to IMP IEA Gallus gallus 58053 R-GGA-419253 https://reactome.org/PathwayBrowser/#/R-GGA-419253 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) <=> inosine 5'-monophosphate + H2O TAS Gallus gallus 58053 R-GGA-420911 https://reactome.org/PathwayBrowser/#/R-GGA-420911 Formation of PPAT dimers IEA Gallus gallus 58053 R-GGA-421179 https://reactome.org/PathwayBrowser/#/R-GGA-421179 inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate IEA Gallus gallus 58053 R-GGA-421201 https://reactome.org/PathwayBrowser/#/R-GGA-421201 inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate IEA Gallus gallus 58053 R-GGA-421222 https://reactome.org/PathwayBrowser/#/R-GGA-421222 inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ IEA Gallus gallus 58053 R-GGA-514604 https://reactome.org/PathwayBrowser/#/R-GGA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Gallus gallus 58053 R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus 58053 R-GGA-73797 https://reactome.org/PathwayBrowser/#/R-GGA-73797 FAICAR => IMP + H2O IEA Gallus gallus 58053 R-GGA-74215 https://reactome.org/PathwayBrowser/#/R-GGA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Gallus gallus 58053 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 58053 R-GGA-76590 https://reactome.org/PathwayBrowser/#/R-GGA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Gallus gallus 58053 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58053 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58053 R-GGA-9754916 https://reactome.org/PathwayBrowser/#/R-GGA-9754916 NT5C2 tetramer phosphorylates RBV IEA Gallus gallus 58053 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 58053 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 58053 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 58053 R-HSA-111285 https://reactome.org/PathwayBrowser/#/R-HSA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer TAS Homo sapiens 58053 R-HSA-111524 https://reactome.org/PathwayBrowser/#/R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] TAS Homo sapiens 58053 R-HSA-2161187 https://reactome.org/PathwayBrowser/#/R-HSA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine TAS Homo sapiens 58053 R-HSA-2162066 https://reactome.org/PathwayBrowser/#/R-HSA-2162066 carbovir + IMP => carbovir monophosphate + inosine TAS Homo sapiens 58053 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 58053 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 58053 R-HSA-2509816 https://reactome.org/PathwayBrowser/#/R-HSA-2509816 NUDT16 hydrolyses IDP to IMP TAS Homo sapiens 58053 R-HSA-2509827 https://reactome.org/PathwayBrowser/#/R-HSA-2509827 ITPA hydrolyses ITP to IMP TAS Homo sapiens 58053 R-HSA-514604 https://reactome.org/PathwayBrowser/#/R-HSA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) TAS Homo sapiens 58053 R-HSA-73794 https://reactome.org/PathwayBrowser/#/R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] TAS Homo sapiens 58053 R-HSA-73797 https://reactome.org/PathwayBrowser/#/R-HSA-73797 FAICAR => IMP + H2O TAS Homo sapiens 58053 R-HSA-74215 https://reactome.org/PathwayBrowser/#/R-HSA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 58053 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 58053 R-HSA-76590 https://reactome.org/PathwayBrowser/#/R-HSA-76590 AMP + H2O => IMP + NH4+ (AMPD) TAS Homo sapiens 58053 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58053 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58053 R-HSA-9717182 https://reactome.org/PathwayBrowser/#/R-HSA-9717182 L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP and GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 58053 R-HSA-9717202 https://reactome.org/PathwayBrowser/#/R-HSA-9717202 GNAT3 exchanges GDP for GTP in L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 58053 R-HSA-9717206 https://reactome.org/PathwayBrowser/#/R-HSA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) TAS Homo sapiens 58053 R-HSA-9754916 https://reactome.org/PathwayBrowser/#/R-HSA-9754916 NT5C2 tetramer phosphorylates RBV TAS Homo sapiens 58053 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 58053 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 58053 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 58053 R-MMU-111285 https://reactome.org/PathwayBrowser/#/R-MMU-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Mus musculus 58053 R-MMU-111519 https://reactome.org/PathwayBrowser/#/R-MMU-111519 inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate TAS Mus musculus 58053 R-MMU-111524 https://reactome.org/PathwayBrowser/#/R-MMU-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Mus musculus 58053 R-MMU-2161187 https://reactome.org/PathwayBrowser/#/R-MMU-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Mus musculus 58053 R-MMU-2162066 https://reactome.org/PathwayBrowser/#/R-MMU-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Mus musculus 58053 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 58053 R-MMU-2509816 https://reactome.org/PathwayBrowser/#/R-MMU-2509816 NUDT16 hydrolyses IDP to IMP IEA Mus musculus 58053 R-MMU-2509827 https://reactome.org/PathwayBrowser/#/R-MMU-2509827 ITPA hydrolyses ITP to IMP IEA Mus musculus 58053 R-MMU-514604 https://reactome.org/PathwayBrowser/#/R-MMU-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Mus musculus 58053 R-MMU-73794 https://reactome.org/PathwayBrowser/#/R-MMU-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Mus musculus 58053 R-MMU-73797 https://reactome.org/PathwayBrowser/#/R-MMU-73797 FAICAR => IMP + H2O IEA Mus musculus 58053 R-MMU-74215 https://reactome.org/PathwayBrowser/#/R-MMU-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Mus musculus 58053 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 58053 R-MMU-76590 https://reactome.org/PathwayBrowser/#/R-MMU-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Mus musculus 58053 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 58053 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 58053 R-MMU-9717206 https://reactome.org/PathwayBrowser/#/R-MMU-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Mus musculus 58053 R-MMU-9754916 https://reactome.org/PathwayBrowser/#/R-MMU-9754916 NT5C2 tetramer phosphorylates RBV IEA Mus musculus 58053 R-PFA-111524 https://reactome.org/PathwayBrowser/#/R-PFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Plasmodium falciparum 58053 R-PFA-2509827 https://reactome.org/PathwayBrowser/#/R-PFA-2509827 ITPA hydrolyses ITP to IMP IEA Plasmodium falciparum 58053 R-PFA-73794 https://reactome.org/PathwayBrowser/#/R-PFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Plasmodium falciparum 58053 R-PFA-74215 https://reactome.org/PathwayBrowser/#/R-PFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Plasmodium falciparum 58053 R-PFA-76590 https://reactome.org/PathwayBrowser/#/R-PFA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Plasmodium falciparum 58053 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58053 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58053 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 58053 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 58053 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 58053 R-RNO-111285 https://reactome.org/PathwayBrowser/#/R-RNO-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Rattus norvegicus 58053 R-RNO-111524 https://reactome.org/PathwayBrowser/#/R-RNO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Rattus norvegicus 58053 R-RNO-2162066 https://reactome.org/PathwayBrowser/#/R-RNO-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Rattus norvegicus 58053 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 58053 R-RNO-2509816 https://reactome.org/PathwayBrowser/#/R-RNO-2509816 NUDT16 hydrolyses IDP to IMP IEA Rattus norvegicus 58053 R-RNO-2509827 https://reactome.org/PathwayBrowser/#/R-RNO-2509827 ITPA hydrolyses ITP to IMP IEA Rattus norvegicus 58053 R-RNO-514604 https://reactome.org/PathwayBrowser/#/R-RNO-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Rattus norvegicus 58053 R-RNO-73794 https://reactome.org/PathwayBrowser/#/R-RNO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Rattus norvegicus 58053 R-RNO-73797 https://reactome.org/PathwayBrowser/#/R-RNO-73797 FAICAR => IMP + H2O IEA Rattus norvegicus 58053 R-RNO-74215 https://reactome.org/PathwayBrowser/#/R-RNO-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Rattus norvegicus 58053 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 58053 R-RNO-76590 https://reactome.org/PathwayBrowser/#/R-RNO-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Rattus norvegicus 58053 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58053 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58053 R-RNO-9717206 https://reactome.org/PathwayBrowser/#/R-RNO-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Rattus norvegicus 58053 R-RNO-9754916 https://reactome.org/PathwayBrowser/#/R-RNO-9754916 NT5C2 tetramer phosphorylates RBV IEA Rattus norvegicus 58053 R-SCE-111524 https://reactome.org/PathwayBrowser/#/R-SCE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Saccharomyces cerevisiae 58053 R-SCE-2509827 https://reactome.org/PathwayBrowser/#/R-SCE-2509827 ITPA hydrolyses ITP to IMP IEA Saccharomyces cerevisiae 58053 R-SCE-73794 https://reactome.org/PathwayBrowser/#/R-SCE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Saccharomyces cerevisiae 58053 R-SCE-73797 https://reactome.org/PathwayBrowser/#/R-SCE-73797 FAICAR => IMP + H2O IEA Saccharomyces cerevisiae 58053 R-SCE-76590 https://reactome.org/PathwayBrowser/#/R-SCE-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Saccharomyces cerevisiae 58053 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58053 R-SPO-111524 https://reactome.org/PathwayBrowser/#/R-SPO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Schizosaccharomyces pombe 58053 R-SPO-2509827 https://reactome.org/PathwayBrowser/#/R-SPO-2509827 ITPA hydrolyses ITP to IMP IEA Schizosaccharomyces pombe 58053 R-SPO-73794 https://reactome.org/PathwayBrowser/#/R-SPO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Schizosaccharomyces pombe 58053 R-SPO-73797 https://reactome.org/PathwayBrowser/#/R-SPO-73797 FAICAR => IMP + H2O IEA Schizosaccharomyces pombe 58053 R-SPO-76590 https://reactome.org/PathwayBrowser/#/R-SPO-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Schizosaccharomyces pombe 58053 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58053 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 58053 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 58053 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 58053 R-SSC-111285 https://reactome.org/PathwayBrowser/#/R-SSC-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Sus scrofa 58053 R-SSC-111524 https://reactome.org/PathwayBrowser/#/R-SSC-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Sus scrofa 58053 R-SSC-2161187 https://reactome.org/PathwayBrowser/#/R-SSC-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Sus scrofa 58053 R-SSC-2162066 https://reactome.org/PathwayBrowser/#/R-SSC-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Sus scrofa 58053 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 58053 R-SSC-2509816 https://reactome.org/PathwayBrowser/#/R-SSC-2509816 NUDT16 hydrolyses IDP to IMP IEA Sus scrofa 58053 R-SSC-2509827 https://reactome.org/PathwayBrowser/#/R-SSC-2509827 ITPA hydrolyses ITP to IMP IEA Sus scrofa 58053 R-SSC-514604 https://reactome.org/PathwayBrowser/#/R-SSC-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Sus scrofa 58053 R-SSC-73794 https://reactome.org/PathwayBrowser/#/R-SSC-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Sus scrofa 58053 R-SSC-73797 https://reactome.org/PathwayBrowser/#/R-SSC-73797 FAICAR => IMP + H2O IEA Sus scrofa 58053 R-SSC-74215 https://reactome.org/PathwayBrowser/#/R-SSC-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Sus scrofa 58053 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 58053 R-SSC-76590 https://reactome.org/PathwayBrowser/#/R-SSC-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Sus scrofa 58053 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58053 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58053 R-SSC-9717206 https://reactome.org/PathwayBrowser/#/R-SSC-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Sus scrofa 58053 R-SSC-9754916 https://reactome.org/PathwayBrowser/#/R-SSC-9754916 NT5C2 tetramer phosphorylates RBV IEA Sus scrofa 58053 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 58053 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 58053 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 58053 R-XTR-111285 https://reactome.org/PathwayBrowser/#/R-XTR-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Xenopus tropicalis 58053 R-XTR-111524 https://reactome.org/PathwayBrowser/#/R-XTR-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Xenopus tropicalis 58053 R-XTR-2161187 https://reactome.org/PathwayBrowser/#/R-XTR-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Xenopus tropicalis 58053 R-XTR-2162066 https://reactome.org/PathwayBrowser/#/R-XTR-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Xenopus tropicalis 58053 R-XTR-2509816 https://reactome.org/PathwayBrowser/#/R-XTR-2509816 NUDT16 hydrolyses IDP to IMP IEA Xenopus tropicalis 58053 R-XTR-2509827 https://reactome.org/PathwayBrowser/#/R-XTR-2509827 ITPA hydrolyses ITP to IMP IEA Xenopus tropicalis 58053 R-XTR-514604 https://reactome.org/PathwayBrowser/#/R-XTR-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Xenopus tropicalis 58053 R-XTR-73794 https://reactome.org/PathwayBrowser/#/R-XTR-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Xenopus tropicalis 58053 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 58053 R-XTR-76590 https://reactome.org/PathwayBrowser/#/R-XTR-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Xenopus tropicalis 58053 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58053 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58053 R-XTR-9754916 https://reactome.org/PathwayBrowser/#/R-XTR-9754916 NT5C2 tetramer phosphorylates RBV IEA Xenopus tropicalis 58065 R-BTA-1614524 https://reactome.org/PathwayBrowser/#/R-BTA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Bos taurus 58065 R-BTA-1614567 https://reactome.org/PathwayBrowser/#/R-BTA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Bos taurus 58065 R-BTA-1614631 https://reactome.org/PathwayBrowser/#/R-BTA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Bos taurus 58065 R-BTA-1614654 https://reactome.org/PathwayBrowser/#/R-BTA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Bos taurus 58065 R-BTA-174374 https://reactome.org/PathwayBrowser/#/R-BTA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Bos taurus 58065 R-BTA-174401 https://reactome.org/PathwayBrowser/#/R-BTA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Bos taurus 58065 R-BTA-379464 https://reactome.org/PathwayBrowser/#/R-BTA-379464 COMT transfers Met to DOPAC to form HVA IEA Bos taurus 58065 R-BTA-5696838 https://reactome.org/PathwayBrowser/#/R-BTA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Bos taurus 58065 R-CEL-1614524 https://reactome.org/PathwayBrowser/#/R-CEL-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Caenorhabditis elegans 58065 R-CEL-1614567 https://reactome.org/PathwayBrowser/#/R-CEL-1614567 Excess homocysteine yields homolanthionine and H2S IEA Caenorhabditis elegans 58065 R-CEL-1614631 https://reactome.org/PathwayBrowser/#/R-CEL-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Caenorhabditis elegans 58065 R-CEL-174374 https://reactome.org/PathwayBrowser/#/R-CEL-174374 MTR transfers CH3 from MeCbl to HCYS IEA Caenorhabditis elegans 58065 R-CEL-174401 https://reactome.org/PathwayBrowser/#/R-CEL-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Caenorhabditis elegans 58065 R-CFA-1614524 https://reactome.org/PathwayBrowser/#/R-CFA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Canis familiaris 58065 R-CFA-1614567 https://reactome.org/PathwayBrowser/#/R-CFA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Canis familiaris 58065 R-CFA-1614631 https://reactome.org/PathwayBrowser/#/R-CFA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Canis familiaris 58065 R-CFA-1614654 https://reactome.org/PathwayBrowser/#/R-CFA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Canis familiaris 58065 R-CFA-174374 https://reactome.org/PathwayBrowser/#/R-CFA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Canis familiaris 58065 R-CFA-174401 https://reactome.org/PathwayBrowser/#/R-CFA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Canis familiaris 58065 R-CFA-379464 https://reactome.org/PathwayBrowser/#/R-CFA-379464 COMT transfers Met to DOPAC to form HVA IEA Canis familiaris 58065 R-CFA-5696838 https://reactome.org/PathwayBrowser/#/R-CFA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Canis familiaris 58065 R-DDI-1614524 https://reactome.org/PathwayBrowser/#/R-DDI-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Dictyostelium discoideum 58065 R-DDI-1614567 https://reactome.org/PathwayBrowser/#/R-DDI-1614567 Excess homocysteine yields homolanthionine and H2S IEA Dictyostelium discoideum 58065 R-DDI-1614631 https://reactome.org/PathwayBrowser/#/R-DDI-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Dictyostelium discoideum 58065 R-DDI-174374 https://reactome.org/PathwayBrowser/#/R-DDI-174374 MTR transfers CH3 from MeCbl to HCYS IEA Dictyostelium discoideum 58065 R-DDI-174401 https://reactome.org/PathwayBrowser/#/R-DDI-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Dictyostelium discoideum 58065 R-DME-1614524 https://reactome.org/PathwayBrowser/#/R-DME-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Drosophila melanogaster 58065 R-DME-1614567 https://reactome.org/PathwayBrowser/#/R-DME-1614567 Excess homocysteine yields homolanthionine and H2S IEA Drosophila melanogaster 58065 R-DME-1614631 https://reactome.org/PathwayBrowser/#/R-DME-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Drosophila melanogaster 58065 R-DME-174401 https://reactome.org/PathwayBrowser/#/R-DME-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Drosophila melanogaster 58065 R-DRE-1614524 https://reactome.org/PathwayBrowser/#/R-DRE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Danio rerio 58065 R-DRE-1614567 https://reactome.org/PathwayBrowser/#/R-DRE-1614567 Excess homocysteine yields homolanthionine and H2S IEA Danio rerio 58065 R-DRE-1614631 https://reactome.org/PathwayBrowser/#/R-DRE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Danio rerio 58065 R-DRE-1614654 https://reactome.org/PathwayBrowser/#/R-DRE-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Danio rerio 58065 R-DRE-174401 https://reactome.org/PathwayBrowser/#/R-DRE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Danio rerio 58065 R-DRE-379464 https://reactome.org/PathwayBrowser/#/R-DRE-379464 COMT transfers Met to DOPAC to form HVA IEA Danio rerio 58065 R-DRE-5696838 https://reactome.org/PathwayBrowser/#/R-DRE-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Danio rerio 58065 R-GGA-1614524 https://reactome.org/PathwayBrowser/#/R-GGA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Gallus gallus 58065 R-GGA-1614567 https://reactome.org/PathwayBrowser/#/R-GGA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Gallus gallus 58065 R-GGA-1614631 https://reactome.org/PathwayBrowser/#/R-GGA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Gallus gallus 58065 R-GGA-1614654 https://reactome.org/PathwayBrowser/#/R-GGA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Gallus gallus 58065 R-GGA-174374 https://reactome.org/PathwayBrowser/#/R-GGA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Gallus gallus 58065 R-GGA-174401 https://reactome.org/PathwayBrowser/#/R-GGA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Gallus gallus 58065 R-GGA-379464 https://reactome.org/PathwayBrowser/#/R-GGA-379464 COMT transfers Met to DOPAC to form HVA IEA Gallus gallus 58065 R-GGA-5696838 https://reactome.org/PathwayBrowser/#/R-GGA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Gallus gallus 58065 R-HSA-1614524 https://reactome.org/PathwayBrowser/#/R-HSA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine TAS Homo sapiens 58065 R-HSA-1614567 https://reactome.org/PathwayBrowser/#/R-HSA-1614567 Excess homocysteine yields homolanthionine and H2S TAS Homo sapiens 58065 R-HSA-1614631 https://reactome.org/PathwayBrowser/#/R-HSA-1614631 Homocysteine is degraded to oxobutanoate and H2S TAS Homo sapiens 58065 R-HSA-1614654 https://reactome.org/PathwayBrowser/#/R-HSA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY TAS Homo sapiens 58065 R-HSA-174374 https://reactome.org/PathwayBrowser/#/R-HSA-174374 MTR transfers CH3 from MeCbl to HCYS TAS Homo sapiens 58065 R-HSA-174401 https://reactome.org/PathwayBrowser/#/R-HSA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy TAS Homo sapiens 58065 R-HSA-3322140 https://reactome.org/PathwayBrowser/#/R-HSA-3322140 Defective MTR does not transfer CH3 group from MeCbl to HCYS TAS Homo sapiens 58065 R-HSA-379464 https://reactome.org/PathwayBrowser/#/R-HSA-379464 COMT transfers Met to DOPAC to form HVA TAS Homo sapiens 58065 R-HSA-5696838 https://reactome.org/PathwayBrowser/#/R-HSA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS TAS Homo sapiens 58065 R-MMU-1614524 https://reactome.org/PathwayBrowser/#/R-MMU-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Mus musculus 58065 R-MMU-1614567 https://reactome.org/PathwayBrowser/#/R-MMU-1614567 Excess homocysteine yields homolanthionine and H2S IEA Mus musculus 58065 R-MMU-1614631 https://reactome.org/PathwayBrowser/#/R-MMU-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Mus musculus 58065 R-MMU-1614654 https://reactome.org/PathwayBrowser/#/R-MMU-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Mus musculus 58065 R-MMU-174374 https://reactome.org/PathwayBrowser/#/R-MMU-174374 MTR transfers CH3 from MeCbl to HCYS IEA Mus musculus 58065 R-MMU-174401 https://reactome.org/PathwayBrowser/#/R-MMU-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Mus musculus 58065 R-MMU-379464 https://reactome.org/PathwayBrowser/#/R-MMU-379464 COMT transfers Met to DOPAC to form HVA IEA Mus musculus 58065 R-MMU-5696838 https://reactome.org/PathwayBrowser/#/R-MMU-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Mus musculus 58065 R-RNO-1614524 https://reactome.org/PathwayBrowser/#/R-RNO-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Rattus norvegicus 58065 R-RNO-1614567 https://reactome.org/PathwayBrowser/#/R-RNO-1614567 Excess homocysteine yields homolanthionine and H2S IEA Rattus norvegicus 58065 R-RNO-1614631 https://reactome.org/PathwayBrowser/#/R-RNO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Rattus norvegicus 58065 R-RNO-1614654 https://reactome.org/PathwayBrowser/#/R-RNO-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Rattus norvegicus 58065 R-RNO-174374 https://reactome.org/PathwayBrowser/#/R-RNO-174374 MTR transfers CH3 from MeCbl to HCYS IEA Rattus norvegicus 58065 R-RNO-174401 https://reactome.org/PathwayBrowser/#/R-RNO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Rattus norvegicus 58065 R-RNO-379464 https://reactome.org/PathwayBrowser/#/R-RNO-379464 COMT transfers Met to DOPAC to form HVA IEA Rattus norvegicus 58065 R-RNO-5696838 https://reactome.org/PathwayBrowser/#/R-RNO-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Rattus norvegicus 58065 R-SCE-1614524 https://reactome.org/PathwayBrowser/#/R-SCE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Saccharomyces cerevisiae 58065 R-SCE-1614567 https://reactome.org/PathwayBrowser/#/R-SCE-1614567 Excess homocysteine yields homolanthionine and H2S IEA Saccharomyces cerevisiae 58065 R-SCE-1614631 https://reactome.org/PathwayBrowser/#/R-SCE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Saccharomyces cerevisiae 58065 R-SCE-174401 https://reactome.org/PathwayBrowser/#/R-SCE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Saccharomyces cerevisiae 58065 R-SPO-1614567 https://reactome.org/PathwayBrowser/#/R-SPO-1614567 Excess homocysteine yields homolanthionine and H2S IEA Schizosaccharomyces pombe 58065 R-SPO-1614631 https://reactome.org/PathwayBrowser/#/R-SPO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Schizosaccharomyces pombe 58065 R-SPO-174401 https://reactome.org/PathwayBrowser/#/R-SPO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Schizosaccharomyces pombe 58065 R-SPO-379464 https://reactome.org/PathwayBrowser/#/R-SPO-379464 COMT transfers Met to DOPAC to form HVA IEA Schizosaccharomyces pombe 58065 R-SSC-1614524 https://reactome.org/PathwayBrowser/#/R-SSC-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Sus scrofa 58065 R-SSC-1614567 https://reactome.org/PathwayBrowser/#/R-SSC-1614567 Excess homocysteine yields homolanthionine and H2S IEA Sus scrofa 58065 R-SSC-1614631 https://reactome.org/PathwayBrowser/#/R-SSC-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Sus scrofa 58065 R-SSC-1614654 https://reactome.org/PathwayBrowser/#/R-SSC-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Sus scrofa 58065 R-SSC-174374 https://reactome.org/PathwayBrowser/#/R-SSC-174374 MTR transfers CH3 from MeCbl to HCYS IEA Sus scrofa 58065 R-SSC-174401 https://reactome.org/PathwayBrowser/#/R-SSC-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Sus scrofa 58065 R-SSC-379464 https://reactome.org/PathwayBrowser/#/R-SSC-379464 COMT transfers Met to DOPAC to form HVA IEA Sus scrofa 58065 R-SSC-5696838 https://reactome.org/PathwayBrowser/#/R-SSC-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Sus scrofa 58065 R-XTR-1614567 https://reactome.org/PathwayBrowser/#/R-XTR-1614567 Excess homocysteine yields homolanthionine and H2S IEA Xenopus tropicalis 58065 R-XTR-1614631 https://reactome.org/PathwayBrowser/#/R-XTR-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Xenopus tropicalis 58065 R-XTR-1614654 https://reactome.org/PathwayBrowser/#/R-XTR-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Xenopus tropicalis 58065 R-XTR-174401 https://reactome.org/PathwayBrowser/#/R-XTR-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Xenopus tropicalis 58065 R-XTR-379464 https://reactome.org/PathwayBrowser/#/R-XTR-379464 COMT transfers Met to DOPAC to form HVA IEA Xenopus tropicalis 58065 R-XTR-5696838 https://reactome.org/PathwayBrowser/#/R-XTR-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Xenopus tropicalis 58066 R-BTA-508040 https://reactome.org/PathwayBrowser/#/R-BTA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Bos taurus 58066 R-BTA-70654 https://reactome.org/PathwayBrowser/#/R-BTA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Bos taurus 58066 R-BTA-70666 https://reactome.org/PathwayBrowser/#/R-BTA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Bos taurus 58066 R-BTA-70679 https://reactome.org/PathwayBrowser/#/R-BTA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Bos taurus 58066 R-CEL-508040 https://reactome.org/PathwayBrowser/#/R-CEL-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Caenorhabditis elegans 58066 R-CEL-70654 https://reactome.org/PathwayBrowser/#/R-CEL-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Caenorhabditis elegans 58066 R-CEL-70666 https://reactome.org/PathwayBrowser/#/R-CEL-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Caenorhabditis elegans 58066 R-CFA-508040 https://reactome.org/PathwayBrowser/#/R-CFA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Canis familiaris 58066 R-CFA-70654 https://reactome.org/PathwayBrowser/#/R-CFA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Canis familiaris 58066 R-CFA-70666 https://reactome.org/PathwayBrowser/#/R-CFA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Canis familiaris 58066 R-CFA-70679 https://reactome.org/PathwayBrowser/#/R-CFA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Canis familiaris 58066 R-DDI-70654 https://reactome.org/PathwayBrowser/#/R-DDI-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Dictyostelium discoideum 58066 R-DDI-70666 https://reactome.org/PathwayBrowser/#/R-DDI-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Dictyostelium discoideum 58066 R-DME-508040 https://reactome.org/PathwayBrowser/#/R-DME-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Drosophila melanogaster 58066 R-DME-70654 https://reactome.org/PathwayBrowser/#/R-DME-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Drosophila melanogaster 58066 R-DME-70666 https://reactome.org/PathwayBrowser/#/R-DME-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Drosophila melanogaster 58066 R-DRE-70679 https://reactome.org/PathwayBrowser/#/R-DRE-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Danio rerio 58066 R-GGA-508040 https://reactome.org/PathwayBrowser/#/R-GGA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Gallus gallus 58066 R-GGA-70654 https://reactome.org/PathwayBrowser/#/R-GGA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Gallus gallus 58066 R-GGA-70666 https://reactome.org/PathwayBrowser/#/R-GGA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Gallus gallus 58066 R-GGA-70679 https://reactome.org/PathwayBrowser/#/R-GGA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Gallus gallus 58066 R-HSA-508040 https://reactome.org/PathwayBrowser/#/R-HSA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] TAS Homo sapiens 58066 R-HSA-70654 https://reactome.org/PathwayBrowser/#/R-HSA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] TAS Homo sapiens 58066 R-HSA-70655 https://reactome.org/PathwayBrowser/#/R-HSA-70655 L-glutamate gamma-semialdehyde <=> L-1-pyrroline-5-carboxylate TAS Homo sapiens 58066 R-HSA-70666 https://reactome.org/PathwayBrowser/#/R-HSA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] TAS Homo sapiens 58066 R-HSA-70667 https://reactome.org/PathwayBrowser/#/R-HSA-70667 1PYR-5COOH spontaneously hydrolyses to L-GluSS TAS Homo sapiens 58066 R-HSA-70679 https://reactome.org/PathwayBrowser/#/R-HSA-70679 ALDH4A1 oxidises L-GluSS to Glu TAS Homo sapiens 58066 R-MMU-508040 https://reactome.org/PathwayBrowser/#/R-MMU-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Mus musculus 58066 R-MMU-70654 https://reactome.org/PathwayBrowser/#/R-MMU-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Mus musculus 58066 R-MMU-70666 https://reactome.org/PathwayBrowser/#/R-MMU-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Mus musculus 58066 R-MMU-70679 https://reactome.org/PathwayBrowser/#/R-MMU-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Mus musculus 58066 R-PFA-70654 https://reactome.org/PathwayBrowser/#/R-PFA-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Plasmodium falciparum 58066 R-PFA-70666 https://reactome.org/PathwayBrowser/#/R-PFA-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Plasmodium falciparum 58066 R-RNO-508040 https://reactome.org/PathwayBrowser/#/R-RNO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Rattus norvegicus 58066 R-RNO-70654 https://reactome.org/PathwayBrowser/#/R-RNO-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Rattus norvegicus 58066 R-RNO-70666 https://reactome.org/PathwayBrowser/#/R-RNO-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Rattus norvegicus 58066 R-RNO-70679 https://reactome.org/PathwayBrowser/#/R-RNO-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Rattus norvegicus 58066 R-SCE-508040 https://reactome.org/PathwayBrowser/#/R-SCE-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Saccharomyces cerevisiae 58066 R-SCE-70654 https://reactome.org/PathwayBrowser/#/R-SCE-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Saccharomyces cerevisiae 58066 R-SCE-70666 https://reactome.org/PathwayBrowser/#/R-SCE-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Saccharomyces cerevisiae 58066 R-SPO-508040 https://reactome.org/PathwayBrowser/#/R-SPO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Schizosaccharomyces pombe 58066 R-SPO-70654 https://reactome.org/PathwayBrowser/#/R-SPO-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Schizosaccharomyces pombe 58066 R-SPO-70666 https://reactome.org/PathwayBrowser/#/R-SPO-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Schizosaccharomyces pombe 58066 R-SSC-508040 https://reactome.org/PathwayBrowser/#/R-SSC-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Sus scrofa 58066 R-SSC-70654 https://reactome.org/PathwayBrowser/#/R-SSC-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Sus scrofa 58066 R-SSC-70666 https://reactome.org/PathwayBrowser/#/R-SSC-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Sus scrofa 58066 R-SSC-70679 https://reactome.org/PathwayBrowser/#/R-SSC-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Sus scrofa 58066 R-XTR-508040 https://reactome.org/PathwayBrowser/#/R-XTR-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Xenopus tropicalis 58066 R-XTR-70654 https://reactome.org/PathwayBrowser/#/R-XTR-70654 ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] IEA Xenopus tropicalis 58066 R-XTR-70666 https://reactome.org/PathwayBrowser/#/R-XTR-70666 glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] IEA Xenopus tropicalis 58066 R-XTR-70679 https://reactome.org/PathwayBrowser/#/R-XTR-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Xenopus tropicalis 58069 R-BTA-110137 https://reactome.org/PathwayBrowser/#/R-BTA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Bos taurus 58069 R-BTA-110138 https://reactome.org/PathwayBrowser/#/R-BTA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 58069 R-BTA-446195 https://reactome.org/PathwayBrowser/#/R-BTA-446195 DOLK phosphorylates DCHOL to DOLP IEA Bos taurus 58069 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 58069 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 58069 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 58069 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 58069 R-BTA-6788798 https://reactome.org/PathwayBrowser/#/R-BTA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 58069 R-BTA-6788810 https://reactome.org/PathwayBrowser/#/R-BTA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 58069 R-BTA-73548 https://reactome.org/PathwayBrowser/#/R-BTA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Bos taurus 58069 R-BTA-75125 https://reactome.org/PathwayBrowser/#/R-BTA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Bos taurus 58069 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 58069 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 58069 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 58069 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 58069 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 58069 R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 58069 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 58069 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 58069 R-CEL-110137 https://reactome.org/PathwayBrowser/#/R-CEL-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Caenorhabditis elegans 58069 R-CEL-110138 https://reactome.org/PathwayBrowser/#/R-CEL-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 58069 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 58069 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 58069 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 58069 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 58069 R-CEL-6788810 https://reactome.org/PathwayBrowser/#/R-CEL-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 58069 R-CEL-73548 https://reactome.org/PathwayBrowser/#/R-CEL-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Caenorhabditis elegans 58069 R-CEL-75125 https://reactome.org/PathwayBrowser/#/R-CEL-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Caenorhabditis elegans 58069 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58069 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 58069 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58069 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58069 R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 58069 R-CFA-110137 https://reactome.org/PathwayBrowser/#/R-CFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Canis familiaris 58069 R-CFA-110138 https://reactome.org/PathwayBrowser/#/R-CFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 58069 R-CFA-446195 https://reactome.org/PathwayBrowser/#/R-CFA-446195 DOLK phosphorylates DCHOL to DOLP IEA Canis familiaris 58069 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 58069 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 58069 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 58069 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 58069 R-CFA-6788798 https://reactome.org/PathwayBrowser/#/R-CFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 58069 R-CFA-6788810 https://reactome.org/PathwayBrowser/#/R-CFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 58069 R-CFA-73548 https://reactome.org/PathwayBrowser/#/R-CFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Canis familiaris 58069 R-CFA-75125 https://reactome.org/PathwayBrowser/#/R-CFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Canis familiaris 58069 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58069 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58069 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58069 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58069 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58069 R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58069 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58069 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58069 R-DDI-446195 https://reactome.org/PathwayBrowser/#/R-DDI-446195 DOLK phosphorylates DCHOL to DOLP IEA Dictyostelium discoideum 58069 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 58069 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 58069 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 58069 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 58069 R-DDI-6788798 https://reactome.org/PathwayBrowser/#/R-DDI-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 58069 R-DDI-6788810 https://reactome.org/PathwayBrowser/#/R-DDI-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 58069 R-DDI-73548 https://reactome.org/PathwayBrowser/#/R-DDI-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Dictyostelium discoideum 58069 R-DDI-75125 https://reactome.org/PathwayBrowser/#/R-DDI-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Dictyostelium discoideum 58069 R-DME-110137 https://reactome.org/PathwayBrowser/#/R-DME-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Drosophila melanogaster 58069 R-DME-110138 https://reactome.org/PathwayBrowser/#/R-DME-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 58069 R-DME-446195 https://reactome.org/PathwayBrowser/#/R-DME-446195 DOLK phosphorylates DCHOL to DOLP IEA Drosophila melanogaster 58069 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 58069 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 58069 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 58069 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 58069 R-DME-6788798 https://reactome.org/PathwayBrowser/#/R-DME-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 58069 R-DME-6788810 https://reactome.org/PathwayBrowser/#/R-DME-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 58069 R-DME-73548 https://reactome.org/PathwayBrowser/#/R-DME-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Drosophila melanogaster 58069 R-DME-75125 https://reactome.org/PathwayBrowser/#/R-DME-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Drosophila melanogaster 58069 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 58069 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 58069 R-DRE-110137 https://reactome.org/PathwayBrowser/#/R-DRE-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Danio rerio 58069 R-DRE-110138 https://reactome.org/PathwayBrowser/#/R-DRE-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 58069 R-DRE-446195 https://reactome.org/PathwayBrowser/#/R-DRE-446195 DOLK phosphorylates DCHOL to DOLP IEA Danio rerio 58069 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 58069 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 58069 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 58069 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 58069 R-DRE-6788798 https://reactome.org/PathwayBrowser/#/R-DRE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 58069 R-DRE-6788810 https://reactome.org/PathwayBrowser/#/R-DRE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 58069 R-DRE-73548 https://reactome.org/PathwayBrowser/#/R-DRE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Danio rerio 58069 R-DRE-75125 https://reactome.org/PathwayBrowser/#/R-DRE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Danio rerio 58069 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 58069 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 58069 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 58069 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 58069 R-GGA-110137 https://reactome.org/PathwayBrowser/#/R-GGA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Gallus gallus 58069 R-GGA-110138 https://reactome.org/PathwayBrowser/#/R-GGA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 58069 R-GGA-446195 https://reactome.org/PathwayBrowser/#/R-GGA-446195 DOLK phosphorylates DCHOL to DOLP IEA Gallus gallus 58069 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 58069 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 58069 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 58069 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 58069 R-GGA-6788798 https://reactome.org/PathwayBrowser/#/R-GGA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 58069 R-GGA-6788810 https://reactome.org/PathwayBrowser/#/R-GGA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 58069 R-GGA-73548 https://reactome.org/PathwayBrowser/#/R-GGA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Gallus gallus 58069 R-GGA-75125 https://reactome.org/PathwayBrowser/#/R-GGA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Gallus gallus 58069 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58069 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58069 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58069 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58069 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58069 R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58069 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58069 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58069 R-HSA-110137 https://reactome.org/PathwayBrowser/#/R-HSA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP TAS Homo sapiens 58069 R-HSA-110138 https://reactome.org/PathwayBrowser/#/R-HSA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 58069 R-HSA-446195 https://reactome.org/PathwayBrowser/#/R-HSA-446195 DOLK phosphorylates DCHOL to DOLP TAS Homo sapiens 58069 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 58069 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 58069 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 58069 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 58069 R-HSA-6788798 https://reactome.org/PathwayBrowser/#/R-HSA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 58069 R-HSA-6788810 https://reactome.org/PathwayBrowser/#/R-HSA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 58069 R-HSA-73548 https://reactome.org/PathwayBrowser/#/R-HSA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) TAS Homo sapiens 58069 R-HSA-75125 https://reactome.org/PathwayBrowser/#/R-HSA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) TAS Homo sapiens 58069 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58069 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58069 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58069 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58069 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58069 R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58069 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58069 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58069 R-MMU-110137 https://reactome.org/PathwayBrowser/#/R-MMU-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Mus musculus 58069 R-MMU-110138 https://reactome.org/PathwayBrowser/#/R-MMU-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 58069 R-MMU-446195 https://reactome.org/PathwayBrowser/#/R-MMU-446195 DOLK phosphorylates DCHOL to DOLP IEA Mus musculus 58069 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 58069 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 58069 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 58069 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 58069 R-MMU-6788798 https://reactome.org/PathwayBrowser/#/R-MMU-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 58069 R-MMU-6788810 https://reactome.org/PathwayBrowser/#/R-MMU-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 58069 R-MMU-73548 https://reactome.org/PathwayBrowser/#/R-MMU-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Mus musculus 58069 R-MMU-75125 https://reactome.org/PathwayBrowser/#/R-MMU-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Mus musculus 58069 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 58069 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 58069 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 58069 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 58069 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 58069 R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 58069 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 58069 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 58069 R-PFA-110137 https://reactome.org/PathwayBrowser/#/R-PFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Plasmodium falciparum 58069 R-PFA-110138 https://reactome.org/PathwayBrowser/#/R-PFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 58069 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 58069 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 58069 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 58069 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 58069 R-PFA-6788798 https://reactome.org/PathwayBrowser/#/R-PFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 58069 R-PFA-6788810 https://reactome.org/PathwayBrowser/#/R-PFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 58069 R-PFA-73548 https://reactome.org/PathwayBrowser/#/R-PFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Plasmodium falciparum 58069 R-PFA-75125 https://reactome.org/PathwayBrowser/#/R-PFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Plasmodium falciparum 58069 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 58069 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58069 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58069 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 58069 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58069 R-RNO-110137 https://reactome.org/PathwayBrowser/#/R-RNO-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Rattus norvegicus 58069 R-RNO-110138 https://reactome.org/PathwayBrowser/#/R-RNO-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 58069 R-RNO-446195 https://reactome.org/PathwayBrowser/#/R-RNO-446195 DOLK phosphorylates DCHOL to DOLP IEA Rattus norvegicus 58069 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 58069 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 58069 R-RNO-6788798 https://reactome.org/PathwayBrowser/#/R-RNO-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 58069 R-RNO-6788810 https://reactome.org/PathwayBrowser/#/R-RNO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 58069 R-RNO-73548 https://reactome.org/PathwayBrowser/#/R-RNO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Rattus norvegicus 58069 R-RNO-75125 https://reactome.org/PathwayBrowser/#/R-RNO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Rattus norvegicus 58069 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58069 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58069 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58069 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58069 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58069 R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58069 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58069 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58069 R-SCE-446195 https://reactome.org/PathwayBrowser/#/R-SCE-446195 DOLK phosphorylates DCHOL to DOLP IEA Saccharomyces cerevisiae 58069 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 58069 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 58069 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 58069 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 58069 R-SCE-6788798 https://reactome.org/PathwayBrowser/#/R-SCE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 58069 R-SCE-6788810 https://reactome.org/PathwayBrowser/#/R-SCE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 58069 R-SCE-73548 https://reactome.org/PathwayBrowser/#/R-SCE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Saccharomyces cerevisiae 58069 R-SCE-75125 https://reactome.org/PathwayBrowser/#/R-SCE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Saccharomyces cerevisiae 58069 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58069 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 58069 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58069 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58069 R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 58069 R-SPO-446195 https://reactome.org/PathwayBrowser/#/R-SPO-446195 DOLK phosphorylates DCHOL to DOLP IEA Schizosaccharomyces pombe 58069 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 58069 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 58069 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 58069 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 58069 R-SPO-6788810 https://reactome.org/PathwayBrowser/#/R-SPO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Schizosaccharomyces pombe 58069 R-SPO-73548 https://reactome.org/PathwayBrowser/#/R-SPO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Schizosaccharomyces pombe 58069 R-SPO-75125 https://reactome.org/PathwayBrowser/#/R-SPO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Schizosaccharomyces pombe 58069 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58069 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 58069 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58069 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58069 R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 58069 R-SSC-110137 https://reactome.org/PathwayBrowser/#/R-SSC-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Sus scrofa 58069 R-SSC-110138 https://reactome.org/PathwayBrowser/#/R-SSC-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 58069 R-SSC-446195 https://reactome.org/PathwayBrowser/#/R-SSC-446195 DOLK phosphorylates DCHOL to DOLP IEA Sus scrofa 58069 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 58069 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 58069 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 58069 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 58069 R-SSC-6788798 https://reactome.org/PathwayBrowser/#/R-SSC-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 58069 R-SSC-6788810 https://reactome.org/PathwayBrowser/#/R-SSC-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 58069 R-SSC-73548 https://reactome.org/PathwayBrowser/#/R-SSC-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Sus scrofa 58069 R-SSC-75125 https://reactome.org/PathwayBrowser/#/R-SSC-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Sus scrofa 58069 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58069 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58069 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58069 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58069 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58069 R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58069 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58069 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58069 R-XTR-110137 https://reactome.org/PathwayBrowser/#/R-XTR-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Xenopus tropicalis 58069 R-XTR-110138 https://reactome.org/PathwayBrowser/#/R-XTR-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 58069 R-XTR-446195 https://reactome.org/PathwayBrowser/#/R-XTR-446195 DOLK phosphorylates DCHOL to DOLP IEA Xenopus tropicalis 58069 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 58069 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 58069 R-XTR-6788798 https://reactome.org/PathwayBrowser/#/R-XTR-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 58069 R-XTR-6788810 https://reactome.org/PathwayBrowser/#/R-XTR-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 58069 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58069 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58069 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58069 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58069 R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58069 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58069 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58088 R-BTA-1675795 https://reactome.org/PathwayBrowser/#/R-BTA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Bos taurus 58088 R-BTA-1675836 https://reactome.org/PathwayBrowser/#/R-BTA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Bos taurus 58088 R-BTA-1675939 https://reactome.org/PathwayBrowser/#/R-BTA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Bos taurus 58088 R-BTA-1675961 https://reactome.org/PathwayBrowser/#/R-BTA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Bos taurus 58088 R-BTA-1675994 https://reactome.org/PathwayBrowser/#/R-BTA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Bos taurus 58088 R-BTA-1676005 https://reactome.org/PathwayBrowser/#/R-BTA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Bos taurus 58088 R-BTA-1676020 https://reactome.org/PathwayBrowser/#/R-BTA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Bos taurus 58088 R-BTA-1676024 https://reactome.org/PathwayBrowser/#/R-BTA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Bos taurus 58088 R-BTA-1676114 https://reactome.org/PathwayBrowser/#/R-BTA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Bos taurus 58088 R-BTA-1676134 https://reactome.org/PathwayBrowser/#/R-BTA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Bos taurus 58088 R-BTA-1676141 https://reactome.org/PathwayBrowser/#/R-BTA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Bos taurus 58088 R-BTA-1676145 https://reactome.org/PathwayBrowser/#/R-BTA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Bos taurus 58088 R-BTA-1676162 https://reactome.org/PathwayBrowser/#/R-BTA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Bos taurus 58088 R-BTA-1676164 https://reactome.org/PathwayBrowser/#/R-BTA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Bos taurus 58088 R-BTA-1676174 https://reactome.org/PathwayBrowser/#/R-BTA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Bos taurus 58088 R-BTA-5668629 https://reactome.org/PathwayBrowser/#/R-BTA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Bos taurus 58088 R-BTA-5676229 https://reactome.org/PathwayBrowser/#/R-BTA-5676229 WIPIs bind PI3P IEA Bos taurus 58088 R-BTA-6798174 https://reactome.org/PathwayBrowser/#/R-BTA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Bos taurus 58088 R-BTA-6809325 https://reactome.org/PathwayBrowser/#/R-BTA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Bos taurus 58088 R-BTA-6809720 https://reactome.org/PathwayBrowser/#/R-BTA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Bos taurus 58088 R-BTA-8849969 https://reactome.org/PathwayBrowser/#/R-BTA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Bos taurus 58088 R-BTA-8870489 https://reactome.org/PathwayBrowser/#/R-BTA-8870489 PLEKHA4,(5,6) bind PI3P IEA Bos taurus 58088 R-BTA-8871376 https://reactome.org/PathwayBrowser/#/R-BTA-8871376 p-Y389,400-RUFY1 binds PI3P IEA Bos taurus 58088 R-CEL-1675795 https://reactome.org/PathwayBrowser/#/R-CEL-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Caenorhabditis elegans 58088 R-CEL-1675836 https://reactome.org/PathwayBrowser/#/R-CEL-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Caenorhabditis elegans 58088 R-CEL-1675939 https://reactome.org/PathwayBrowser/#/R-CEL-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Caenorhabditis elegans 58088 R-CEL-1675961 https://reactome.org/PathwayBrowser/#/R-CEL-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Caenorhabditis elegans 58088 R-CEL-1675994 https://reactome.org/PathwayBrowser/#/R-CEL-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Caenorhabditis elegans 58088 R-CEL-1676024 https://reactome.org/PathwayBrowser/#/R-CEL-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Caenorhabditis elegans 58088 R-CEL-1676114 https://reactome.org/PathwayBrowser/#/R-CEL-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Caenorhabditis elegans 58088 R-CEL-1676134 https://reactome.org/PathwayBrowser/#/R-CEL-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Caenorhabditis elegans 58088 R-CEL-1676141 https://reactome.org/PathwayBrowser/#/R-CEL-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Caenorhabditis elegans 58088 R-CEL-1676145 https://reactome.org/PathwayBrowser/#/R-CEL-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Caenorhabditis elegans 58088 R-CEL-1676162 https://reactome.org/PathwayBrowser/#/R-CEL-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Caenorhabditis elegans 58088 R-CEL-1676164 https://reactome.org/PathwayBrowser/#/R-CEL-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Caenorhabditis elegans 58088 R-CEL-5676229 https://reactome.org/PathwayBrowser/#/R-CEL-5676229 WIPIs bind PI3P IEA Caenorhabditis elegans 58088 R-CEL-6798174 https://reactome.org/PathwayBrowser/#/R-CEL-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Caenorhabditis elegans 58088 R-CEL-6809325 https://reactome.org/PathwayBrowser/#/R-CEL-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Caenorhabditis elegans 58088 R-CEL-6809720 https://reactome.org/PathwayBrowser/#/R-CEL-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Caenorhabditis elegans 58088 R-CEL-8849969 https://reactome.org/PathwayBrowser/#/R-CEL-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Caenorhabditis elegans 58088 R-CFA-1675795 https://reactome.org/PathwayBrowser/#/R-CFA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Canis familiaris 58088 R-CFA-1675836 https://reactome.org/PathwayBrowser/#/R-CFA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Canis familiaris 58088 R-CFA-1675939 https://reactome.org/PathwayBrowser/#/R-CFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Canis familiaris 58088 R-CFA-1675961 https://reactome.org/PathwayBrowser/#/R-CFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Canis familiaris 58088 R-CFA-1675994 https://reactome.org/PathwayBrowser/#/R-CFA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Canis familiaris 58088 R-CFA-1676005 https://reactome.org/PathwayBrowser/#/R-CFA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Canis familiaris 58088 R-CFA-1676020 https://reactome.org/PathwayBrowser/#/R-CFA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Canis familiaris 58088 R-CFA-1676024 https://reactome.org/PathwayBrowser/#/R-CFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Canis familiaris 58088 R-CFA-1676114 https://reactome.org/PathwayBrowser/#/R-CFA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Canis familiaris 58088 R-CFA-1676134 https://reactome.org/PathwayBrowser/#/R-CFA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Canis familiaris 58088 R-CFA-1676141 https://reactome.org/PathwayBrowser/#/R-CFA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Canis familiaris 58088 R-CFA-1676145 https://reactome.org/PathwayBrowser/#/R-CFA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Canis familiaris 58088 R-CFA-1676162 https://reactome.org/PathwayBrowser/#/R-CFA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Canis familiaris 58088 R-CFA-1676164 https://reactome.org/PathwayBrowser/#/R-CFA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Canis familiaris 58088 R-CFA-1676174 https://reactome.org/PathwayBrowser/#/R-CFA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Canis familiaris 58088 R-CFA-5668629 https://reactome.org/PathwayBrowser/#/R-CFA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Canis familiaris 58088 R-CFA-5676229 https://reactome.org/PathwayBrowser/#/R-CFA-5676229 WIPIs bind PI3P IEA Canis familiaris 58088 R-CFA-6798174 https://reactome.org/PathwayBrowser/#/R-CFA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Canis familiaris 58088 R-CFA-6809325 https://reactome.org/PathwayBrowser/#/R-CFA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Canis familiaris 58088 R-CFA-6809720 https://reactome.org/PathwayBrowser/#/R-CFA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Canis familiaris 58088 R-CFA-8849969 https://reactome.org/PathwayBrowser/#/R-CFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Canis familiaris 58088 R-CFA-8870489 https://reactome.org/PathwayBrowser/#/R-CFA-8870489 PLEKHA4,(5,6) bind PI3P IEA Canis familiaris 58088 R-CFA-8871376 https://reactome.org/PathwayBrowser/#/R-CFA-8871376 p-Y389,400-RUFY1 binds PI3P IEA Canis familiaris 58088 R-DDI-1675795 https://reactome.org/PathwayBrowser/#/R-DDI-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Dictyostelium discoideum 58088 R-DDI-1675836 https://reactome.org/PathwayBrowser/#/R-DDI-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Dictyostelium discoideum 58088 R-DDI-1675939 https://reactome.org/PathwayBrowser/#/R-DDI-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Dictyostelium discoideum 58088 R-DDI-1675961 https://reactome.org/PathwayBrowser/#/R-DDI-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Dictyostelium discoideum 58088 R-DDI-1675994 https://reactome.org/PathwayBrowser/#/R-DDI-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Dictyostelium discoideum 58088 R-DDI-1676024 https://reactome.org/PathwayBrowser/#/R-DDI-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Dictyostelium discoideum 58088 R-DDI-1676114 https://reactome.org/PathwayBrowser/#/R-DDI-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Dictyostelium discoideum 58088 R-DDI-1676134 https://reactome.org/PathwayBrowser/#/R-DDI-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Dictyostelium discoideum 58088 R-DDI-1676141 https://reactome.org/PathwayBrowser/#/R-DDI-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Dictyostelium discoideum 58088 R-DDI-1676145 https://reactome.org/PathwayBrowser/#/R-DDI-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Dictyostelium discoideum 58088 R-DDI-5676229 https://reactome.org/PathwayBrowser/#/R-DDI-5676229 WIPIs bind PI3P IEA Dictyostelium discoideum 58088 R-DDI-6798174 https://reactome.org/PathwayBrowser/#/R-DDI-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Dictyostelium discoideum 58088 R-DDI-6809325 https://reactome.org/PathwayBrowser/#/R-DDI-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Dictyostelium discoideum 58088 R-DDI-6809720 https://reactome.org/PathwayBrowser/#/R-DDI-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Dictyostelium discoideum 58088 R-DDI-8849969 https://reactome.org/PathwayBrowser/#/R-DDI-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Dictyostelium discoideum 58088 R-DDI-8870489 https://reactome.org/PathwayBrowser/#/R-DDI-8870489 PLEKHA4,(5,6) bind PI3P IEA Dictyostelium discoideum 58088 R-DME-1675795 https://reactome.org/PathwayBrowser/#/R-DME-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Drosophila melanogaster 58088 R-DME-1675836 https://reactome.org/PathwayBrowser/#/R-DME-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Drosophila melanogaster 58088 R-DME-1675939 https://reactome.org/PathwayBrowser/#/R-DME-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Drosophila melanogaster 58088 R-DME-1675961 https://reactome.org/PathwayBrowser/#/R-DME-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Drosophila melanogaster 58088 R-DME-1675994 https://reactome.org/PathwayBrowser/#/R-DME-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Drosophila melanogaster 58088 R-DME-1676024 https://reactome.org/PathwayBrowser/#/R-DME-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Drosophila melanogaster 58088 R-DME-1676114 https://reactome.org/PathwayBrowser/#/R-DME-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Drosophila melanogaster 58088 R-DME-1676134 https://reactome.org/PathwayBrowser/#/R-DME-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Drosophila melanogaster 58088 R-DME-1676141 https://reactome.org/PathwayBrowser/#/R-DME-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Drosophila melanogaster 58088 R-DME-1676145 https://reactome.org/PathwayBrowser/#/R-DME-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Drosophila melanogaster 58088 R-DME-1676162 https://reactome.org/PathwayBrowser/#/R-DME-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Drosophila melanogaster 58088 R-DME-1676164 https://reactome.org/PathwayBrowser/#/R-DME-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Drosophila melanogaster 58088 R-DME-5676229 https://reactome.org/PathwayBrowser/#/R-DME-5676229 WIPIs bind PI3P IEA Drosophila melanogaster 58088 R-DME-6798174 https://reactome.org/PathwayBrowser/#/R-DME-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Drosophila melanogaster 58088 R-DME-6809325 https://reactome.org/PathwayBrowser/#/R-DME-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Drosophila melanogaster 58088 R-DME-6809720 https://reactome.org/PathwayBrowser/#/R-DME-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Drosophila melanogaster 58088 R-DME-8849969 https://reactome.org/PathwayBrowser/#/R-DME-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Drosophila melanogaster 58088 R-DME-8870489 https://reactome.org/PathwayBrowser/#/R-DME-8870489 PLEKHA4,(5,6) bind PI3P IEA Drosophila melanogaster 58088 R-DME-8871376 https://reactome.org/PathwayBrowser/#/R-DME-8871376 p-Y389,400-RUFY1 binds PI3P IEA Drosophila melanogaster 58088 R-DRE-1675795 https://reactome.org/PathwayBrowser/#/R-DRE-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Danio rerio 58088 R-DRE-1675994 https://reactome.org/PathwayBrowser/#/R-DRE-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Danio rerio 58088 R-DRE-1676114 https://reactome.org/PathwayBrowser/#/R-DRE-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Danio rerio 58088 R-DRE-1676134 https://reactome.org/PathwayBrowser/#/R-DRE-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Danio rerio 58088 R-DRE-1676141 https://reactome.org/PathwayBrowser/#/R-DRE-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Danio rerio 58088 R-DRE-1676145 https://reactome.org/PathwayBrowser/#/R-DRE-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Danio rerio 58088 R-DRE-1676162 https://reactome.org/PathwayBrowser/#/R-DRE-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Danio rerio 58088 R-DRE-1676164 https://reactome.org/PathwayBrowser/#/R-DRE-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Danio rerio 58088 R-DRE-5668629 https://reactome.org/PathwayBrowser/#/R-DRE-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Danio rerio 58088 R-DRE-5676229 https://reactome.org/PathwayBrowser/#/R-DRE-5676229 WIPIs bind PI3P IEA Danio rerio 58088 R-DRE-6809325 https://reactome.org/PathwayBrowser/#/R-DRE-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Danio rerio 58088 R-DRE-6809720 https://reactome.org/PathwayBrowser/#/R-DRE-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Danio rerio 58088 R-DRE-8849969 https://reactome.org/PathwayBrowser/#/R-DRE-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Danio rerio 58088 R-GGA-1675795 https://reactome.org/PathwayBrowser/#/R-GGA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Gallus gallus 58088 R-GGA-1675836 https://reactome.org/PathwayBrowser/#/R-GGA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Gallus gallus 58088 R-GGA-1675939 https://reactome.org/PathwayBrowser/#/R-GGA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Gallus gallus 58088 R-GGA-1675961 https://reactome.org/PathwayBrowser/#/R-GGA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Gallus gallus 58088 R-GGA-1675994 https://reactome.org/PathwayBrowser/#/R-GGA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Gallus gallus 58088 R-GGA-1676005 https://reactome.org/PathwayBrowser/#/R-GGA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Gallus gallus 58088 R-GGA-1676020 https://reactome.org/PathwayBrowser/#/R-GGA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Gallus gallus 58088 R-GGA-1676024 https://reactome.org/PathwayBrowser/#/R-GGA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Gallus gallus 58088 R-GGA-1676114 https://reactome.org/PathwayBrowser/#/R-GGA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Gallus gallus 58088 R-GGA-1676134 https://reactome.org/PathwayBrowser/#/R-GGA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Gallus gallus 58088 R-GGA-1676141 https://reactome.org/PathwayBrowser/#/R-GGA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Gallus gallus 58088 R-GGA-1676145 https://reactome.org/PathwayBrowser/#/R-GGA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Gallus gallus 58088 R-GGA-1676162 https://reactome.org/PathwayBrowser/#/R-GGA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Gallus gallus 58088 R-GGA-1676164 https://reactome.org/PathwayBrowser/#/R-GGA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Gallus gallus 58088 R-GGA-1676174 https://reactome.org/PathwayBrowser/#/R-GGA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Gallus gallus 58088 R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus 58088 R-GGA-5676229 https://reactome.org/PathwayBrowser/#/R-GGA-5676229 WIPIs bind PI3P IEA Gallus gallus 58088 R-GGA-6798174 https://reactome.org/PathwayBrowser/#/R-GGA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Gallus gallus 58088 R-GGA-6809325 https://reactome.org/PathwayBrowser/#/R-GGA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Gallus gallus 58088 R-GGA-6809720 https://reactome.org/PathwayBrowser/#/R-GGA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Gallus gallus 58088 R-GGA-8849969 https://reactome.org/PathwayBrowser/#/R-GGA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Gallus gallus 58088 R-GGA-8871376 https://reactome.org/PathwayBrowser/#/R-GGA-8871376 p-Y389,400-RUFY1 binds PI3P IEA Gallus gallus 58088 R-HSA-1675795 https://reactome.org/PathwayBrowser/#/R-HSA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane TAS Homo sapiens 58088 R-HSA-1675836 https://reactome.org/PathwayBrowser/#/R-HSA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane TAS Homo sapiens 58088 R-HSA-1675910 https://reactome.org/PathwayBrowser/#/R-HSA-1675910 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the late endosome membrane IEA Homo sapiens 58088 R-HSA-1675921 https://reactome.org/PathwayBrowser/#/R-HSA-1675921 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the Golgi membrane IEA Homo sapiens 58088 R-HSA-1675939 https://reactome.org/PathwayBrowser/#/R-HSA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane TAS Homo sapiens 58088 R-HSA-1675961 https://reactome.org/PathwayBrowser/#/R-HSA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane TAS Homo sapiens 58088 R-HSA-1675994 https://reactome.org/PathwayBrowser/#/R-HSA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane TAS Homo sapiens 58088 R-HSA-1676005 https://reactome.org/PathwayBrowser/#/R-HSA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane TAS Homo sapiens 58088 R-HSA-1676020 https://reactome.org/PathwayBrowser/#/R-HSA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane TAS Homo sapiens 58088 R-HSA-1676024 https://reactome.org/PathwayBrowser/#/R-HSA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane TAS Homo sapiens 58088 R-HSA-1676114 https://reactome.org/PathwayBrowser/#/R-HSA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane TAS Homo sapiens 58088 R-HSA-1676134 https://reactome.org/PathwayBrowser/#/R-HSA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane TAS Homo sapiens 58088 R-HSA-1676141 https://reactome.org/PathwayBrowser/#/R-HSA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane TAS Homo sapiens 58088 R-HSA-1676145 https://reactome.org/PathwayBrowser/#/R-HSA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane TAS Homo sapiens 58088 R-HSA-1676162 https://reactome.org/PathwayBrowser/#/R-HSA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane TAS Homo sapiens 58088 R-HSA-1676164 https://reactome.org/PathwayBrowser/#/R-HSA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane TAS Homo sapiens 58088 R-HSA-1676168 https://reactome.org/PathwayBrowser/#/R-HSA-1676168 PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane IEA Homo sapiens 58088 R-HSA-1676174 https://reactome.org/PathwayBrowser/#/R-HSA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane TAS Homo sapiens 58088 R-HSA-5668629 https://reactome.org/PathwayBrowser/#/R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP TAS Homo sapiens 58088 R-HSA-5676229 https://reactome.org/PathwayBrowser/#/R-HSA-5676229 WIPIs bind PI3P TAS Homo sapiens 58088 R-HSA-6798174 https://reactome.org/PathwayBrowser/#/R-HSA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P TAS Homo sapiens 58088 R-HSA-6809325 https://reactome.org/PathwayBrowser/#/R-HSA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane TAS Homo sapiens 58088 R-HSA-6809720 https://reactome.org/PathwayBrowser/#/R-HSA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 TAS Homo sapiens 58088 R-HSA-6809975 https://reactome.org/PathwayBrowser/#/R-HSA-6809975 PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane IEA Homo sapiens 58088 R-HSA-8849969 https://reactome.org/PathwayBrowser/#/R-HSA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane TAS Homo sapiens 58088 R-HSA-8870489 https://reactome.org/PathwayBrowser/#/R-HSA-8870489 PLEKHA4,(5,6) bind PI3P TAS Homo sapiens 58088 R-HSA-8871376 https://reactome.org/PathwayBrowser/#/R-HSA-8871376 p-Y389,400-RUFY1 binds PI3P TAS Homo sapiens 58088 R-MMU-1675795 https://reactome.org/PathwayBrowser/#/R-MMU-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Mus musculus 58088 R-MMU-1675836 https://reactome.org/PathwayBrowser/#/R-MMU-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Mus musculus 58088 R-MMU-1675939 https://reactome.org/PathwayBrowser/#/R-MMU-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Mus musculus 58088 R-MMU-1675961 https://reactome.org/PathwayBrowser/#/R-MMU-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Mus musculus 58088 R-MMU-1675994 https://reactome.org/PathwayBrowser/#/R-MMU-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Mus musculus 58088 R-MMU-1676005 https://reactome.org/PathwayBrowser/#/R-MMU-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Mus musculus 58088 R-MMU-1676020 https://reactome.org/PathwayBrowser/#/R-MMU-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Mus musculus 58088 R-MMU-1676024 https://reactome.org/PathwayBrowser/#/R-MMU-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Mus musculus 58088 R-MMU-1676114 https://reactome.org/PathwayBrowser/#/R-MMU-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Mus musculus 58088 R-MMU-1676134 https://reactome.org/PathwayBrowser/#/R-MMU-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Mus musculus 58088 R-MMU-1676141 https://reactome.org/PathwayBrowser/#/R-MMU-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Mus musculus 58088 R-MMU-1676145 https://reactome.org/PathwayBrowser/#/R-MMU-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Mus musculus 58088 R-MMU-1676162 https://reactome.org/PathwayBrowser/#/R-MMU-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Mus musculus 58088 R-MMU-1676164 https://reactome.org/PathwayBrowser/#/R-MMU-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Mus musculus 58088 R-MMU-1676174 https://reactome.org/PathwayBrowser/#/R-MMU-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Mus musculus 58088 R-MMU-5668629 https://reactome.org/PathwayBrowser/#/R-MMU-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Mus musculus 58088 R-MMU-5676229 https://reactome.org/PathwayBrowser/#/R-MMU-5676229 WIPIs bind PI3P IEA Mus musculus 58088 R-MMU-6798174 https://reactome.org/PathwayBrowser/#/R-MMU-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Mus musculus 58088 R-MMU-6809325 https://reactome.org/PathwayBrowser/#/R-MMU-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Mus musculus 58088 R-MMU-6809720 https://reactome.org/PathwayBrowser/#/R-MMU-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Mus musculus 58088 R-MMU-6809977 https://reactome.org/PathwayBrowser/#/R-MMU-6809977 PI3P is dephosphorylated to PI by the Mtmr2:Sbf2 tetramer at the plasma membrane TAS Mus musculus 58088 R-MMU-8849969 https://reactome.org/PathwayBrowser/#/R-MMU-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Mus musculus 58088 R-MMU-8870489 https://reactome.org/PathwayBrowser/#/R-MMU-8870489 PLEKHA4,(5,6) bind PI3P IEA Mus musculus 58088 R-MMU-8871376 https://reactome.org/PathwayBrowser/#/R-MMU-8871376 p-Y389,400-RUFY1 binds PI3P IEA Mus musculus 58088 R-NUL-1675886 https://reactome.org/PathwayBrowser/#/R-NUL-1675886 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the early endosome membrane TAS Mus musculus 58088 R-NUL-1675925 https://reactome.org/PathwayBrowser/#/R-NUL-1675925 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the late endosome membrane TAS Mus musculus 58088 R-NUL-1675982 https://reactome.org/PathwayBrowser/#/R-NUL-1675982 PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the Golgi membrane TAS Mus musculus 58088 R-PFA-1675836 https://reactome.org/PathwayBrowser/#/R-PFA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Plasmodium falciparum 58088 R-PFA-1675939 https://reactome.org/PathwayBrowser/#/R-PFA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Plasmodium falciparum 58088 R-PFA-1675961 https://reactome.org/PathwayBrowser/#/R-PFA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Plasmodium falciparum 58088 R-PFA-1675994 https://reactome.org/PathwayBrowser/#/R-PFA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Plasmodium falciparum 58088 R-PFA-1676024 https://reactome.org/PathwayBrowser/#/R-PFA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Plasmodium falciparum 58088 R-PFA-1676114 https://reactome.org/PathwayBrowser/#/R-PFA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Plasmodium falciparum 58088 R-PFA-1676134 https://reactome.org/PathwayBrowser/#/R-PFA-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Plasmodium falciparum 58088 R-PFA-1676145 https://reactome.org/PathwayBrowser/#/R-PFA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Plasmodium falciparum 58088 R-PFA-6798174 https://reactome.org/PathwayBrowser/#/R-PFA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Plasmodium falciparum 58088 R-PFA-8849969 https://reactome.org/PathwayBrowser/#/R-PFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Plasmodium falciparum 58088 R-RNO-1675795 https://reactome.org/PathwayBrowser/#/R-RNO-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Rattus norvegicus 58088 R-RNO-1675836 https://reactome.org/PathwayBrowser/#/R-RNO-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Rattus norvegicus 58088 R-RNO-1675939 https://reactome.org/PathwayBrowser/#/R-RNO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Rattus norvegicus 58088 R-RNO-1675961 https://reactome.org/PathwayBrowser/#/R-RNO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Rattus norvegicus 58088 R-RNO-1675994 https://reactome.org/PathwayBrowser/#/R-RNO-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus 58088 R-RNO-1676005 https://reactome.org/PathwayBrowser/#/R-RNO-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Rattus norvegicus 58088 R-RNO-1676020 https://reactome.org/PathwayBrowser/#/R-RNO-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Rattus norvegicus 58088 R-RNO-1676024 https://reactome.org/PathwayBrowser/#/R-RNO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Rattus norvegicus 58088 R-RNO-1676114 https://reactome.org/PathwayBrowser/#/R-RNO-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Rattus norvegicus 58088 R-RNO-1676134 https://reactome.org/PathwayBrowser/#/R-RNO-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Rattus norvegicus 58088 R-RNO-1676141 https://reactome.org/PathwayBrowser/#/R-RNO-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Rattus norvegicus 58088 R-RNO-1676145 https://reactome.org/PathwayBrowser/#/R-RNO-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Rattus norvegicus 58088 R-RNO-1676162 https://reactome.org/PathwayBrowser/#/R-RNO-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Rattus norvegicus 58088 R-RNO-1676164 https://reactome.org/PathwayBrowser/#/R-RNO-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Rattus norvegicus 58088 R-RNO-1676174 https://reactome.org/PathwayBrowser/#/R-RNO-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Rattus norvegicus 58088 R-RNO-5668629 https://reactome.org/PathwayBrowser/#/R-RNO-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Rattus norvegicus 58088 R-RNO-5676229 https://reactome.org/PathwayBrowser/#/R-RNO-5676229 WIPIs bind PI3P IEA Rattus norvegicus 58088 R-RNO-6798174 https://reactome.org/PathwayBrowser/#/R-RNO-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Rattus norvegicus 58088 R-RNO-6809325 https://reactome.org/PathwayBrowser/#/R-RNO-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Rattus norvegicus 58088 R-RNO-6809720 https://reactome.org/PathwayBrowser/#/R-RNO-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Rattus norvegicus 58088 R-RNO-8849969 https://reactome.org/PathwayBrowser/#/R-RNO-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Rattus norvegicus 58088 R-RNO-8870489 https://reactome.org/PathwayBrowser/#/R-RNO-8870489 PLEKHA4,(5,6) bind PI3P IEA Rattus norvegicus 58088 R-RNO-8871376 https://reactome.org/PathwayBrowser/#/R-RNO-8871376 p-Y389,400-RUFY1 binds PI3P IEA Rattus norvegicus 58088 R-SCE-1675795 https://reactome.org/PathwayBrowser/#/R-SCE-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Saccharomyces cerevisiae 58088 R-SCE-1675836 https://reactome.org/PathwayBrowser/#/R-SCE-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Saccharomyces cerevisiae 58088 R-SCE-1675939 https://reactome.org/PathwayBrowser/#/R-SCE-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Saccharomyces cerevisiae 58088 R-SCE-1675961 https://reactome.org/PathwayBrowser/#/R-SCE-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Saccharomyces cerevisiae 58088 R-SCE-1675994 https://reactome.org/PathwayBrowser/#/R-SCE-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Saccharomyces cerevisiae 58088 R-SCE-1676024 https://reactome.org/PathwayBrowser/#/R-SCE-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Saccharomyces cerevisiae 58088 R-SCE-1676114 https://reactome.org/PathwayBrowser/#/R-SCE-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Saccharomyces cerevisiae 58088 R-SCE-1676134 https://reactome.org/PathwayBrowser/#/R-SCE-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Saccharomyces cerevisiae 58088 R-SCE-1676141 https://reactome.org/PathwayBrowser/#/R-SCE-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Saccharomyces cerevisiae 58088 R-SCE-1676145 https://reactome.org/PathwayBrowser/#/R-SCE-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Saccharomyces cerevisiae 58088 R-SCE-5676229 https://reactome.org/PathwayBrowser/#/R-SCE-5676229 WIPIs bind PI3P IEA Saccharomyces cerevisiae 58088 R-SCE-6798174 https://reactome.org/PathwayBrowser/#/R-SCE-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Saccharomyces cerevisiae 58088 R-SCE-6809325 https://reactome.org/PathwayBrowser/#/R-SCE-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Saccharomyces cerevisiae 58088 R-SCE-6809720 https://reactome.org/PathwayBrowser/#/R-SCE-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Saccharomyces cerevisiae 58088 R-SPO-1675795 https://reactome.org/PathwayBrowser/#/R-SPO-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Schizosaccharomyces pombe 58088 R-SPO-1675836 https://reactome.org/PathwayBrowser/#/R-SPO-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Schizosaccharomyces pombe 58088 R-SPO-1675939 https://reactome.org/PathwayBrowser/#/R-SPO-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Schizosaccharomyces pombe 58088 R-SPO-1675961 https://reactome.org/PathwayBrowser/#/R-SPO-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Schizosaccharomyces pombe 58088 R-SPO-1675994 https://reactome.org/PathwayBrowser/#/R-SPO-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Schizosaccharomyces pombe 58088 R-SPO-1676024 https://reactome.org/PathwayBrowser/#/R-SPO-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Schizosaccharomyces pombe 58088 R-SPO-1676114 https://reactome.org/PathwayBrowser/#/R-SPO-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Schizosaccharomyces pombe 58088 R-SPO-1676134 https://reactome.org/PathwayBrowser/#/R-SPO-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Schizosaccharomyces pombe 58088 R-SPO-1676141 https://reactome.org/PathwayBrowser/#/R-SPO-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Schizosaccharomyces pombe 58088 R-SPO-1676145 https://reactome.org/PathwayBrowser/#/R-SPO-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Schizosaccharomyces pombe 58088 R-SPO-5676229 https://reactome.org/PathwayBrowser/#/R-SPO-5676229 WIPIs bind PI3P IEA Schizosaccharomyces pombe 58088 R-SPO-6798174 https://reactome.org/PathwayBrowser/#/R-SPO-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Schizosaccharomyces pombe 58088 R-SPO-6809325 https://reactome.org/PathwayBrowser/#/R-SPO-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Schizosaccharomyces pombe 58088 R-SPO-6809720 https://reactome.org/PathwayBrowser/#/R-SPO-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Schizosaccharomyces pombe 58088 R-SSC-1675795 https://reactome.org/PathwayBrowser/#/R-SSC-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Sus scrofa 58088 R-SSC-1675836 https://reactome.org/PathwayBrowser/#/R-SSC-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Sus scrofa 58088 R-SSC-1675939 https://reactome.org/PathwayBrowser/#/R-SSC-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Sus scrofa 58088 R-SSC-1675961 https://reactome.org/PathwayBrowser/#/R-SSC-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Sus scrofa 58088 R-SSC-1675994 https://reactome.org/PathwayBrowser/#/R-SSC-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Sus scrofa 58088 R-SSC-1676005 https://reactome.org/PathwayBrowser/#/R-SSC-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Sus scrofa 58088 R-SSC-1676020 https://reactome.org/PathwayBrowser/#/R-SSC-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Sus scrofa 58088 R-SSC-1676024 https://reactome.org/PathwayBrowser/#/R-SSC-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Sus scrofa 58088 R-SSC-1676114 https://reactome.org/PathwayBrowser/#/R-SSC-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Sus scrofa 58088 R-SSC-1676134 https://reactome.org/PathwayBrowser/#/R-SSC-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Sus scrofa 58088 R-SSC-1676141 https://reactome.org/PathwayBrowser/#/R-SSC-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Sus scrofa 58088 R-SSC-1676145 https://reactome.org/PathwayBrowser/#/R-SSC-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Sus scrofa 58088 R-SSC-1676162 https://reactome.org/PathwayBrowser/#/R-SSC-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Sus scrofa 58088 R-SSC-1676164 https://reactome.org/PathwayBrowser/#/R-SSC-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Sus scrofa 58088 R-SSC-1676174 https://reactome.org/PathwayBrowser/#/R-SSC-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Sus scrofa 58088 R-SSC-5668629 https://reactome.org/PathwayBrowser/#/R-SSC-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Sus scrofa 58088 R-SSC-5676229 https://reactome.org/PathwayBrowser/#/R-SSC-5676229 WIPIs bind PI3P IEA Sus scrofa 58088 R-SSC-6798174 https://reactome.org/PathwayBrowser/#/R-SSC-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Sus scrofa 58088 R-SSC-6809325 https://reactome.org/PathwayBrowser/#/R-SSC-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Sus scrofa 58088 R-SSC-6809720 https://reactome.org/PathwayBrowser/#/R-SSC-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Sus scrofa 58088 R-SSC-8849969 https://reactome.org/PathwayBrowser/#/R-SSC-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Sus scrofa 58088 R-SSC-8870489 https://reactome.org/PathwayBrowser/#/R-SSC-8870489 PLEKHA4,(5,6) bind PI3P IEA Sus scrofa 58088 R-SSC-8871376 https://reactome.org/PathwayBrowser/#/R-SSC-8871376 p-Y389,400-RUFY1 binds PI3P IEA Sus scrofa 58088 R-XTR-1675795 https://reactome.org/PathwayBrowser/#/R-XTR-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Xenopus tropicalis 58088 R-XTR-1675836 https://reactome.org/PathwayBrowser/#/R-XTR-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Xenopus tropicalis 58088 R-XTR-1675939 https://reactome.org/PathwayBrowser/#/R-XTR-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Xenopus tropicalis 58088 R-XTR-1675961 https://reactome.org/PathwayBrowser/#/R-XTR-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Xenopus tropicalis 58088 R-XTR-1675994 https://reactome.org/PathwayBrowser/#/R-XTR-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Xenopus tropicalis 58088 R-XTR-1676024 https://reactome.org/PathwayBrowser/#/R-XTR-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Xenopus tropicalis 58088 R-XTR-1676141 https://reactome.org/PathwayBrowser/#/R-XTR-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Xenopus tropicalis 58088 R-XTR-1676145 https://reactome.org/PathwayBrowser/#/R-XTR-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Xenopus tropicalis 58088 R-XTR-1676162 https://reactome.org/PathwayBrowser/#/R-XTR-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Xenopus tropicalis 58088 R-XTR-1676164 https://reactome.org/PathwayBrowser/#/R-XTR-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Xenopus tropicalis 58088 R-XTR-5668629 https://reactome.org/PathwayBrowser/#/R-XTR-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Xenopus tropicalis 58088 R-XTR-5676229 https://reactome.org/PathwayBrowser/#/R-XTR-5676229 WIPIs bind PI3P IEA Xenopus tropicalis 58088 R-XTR-6809720 https://reactome.org/PathwayBrowser/#/R-XTR-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Xenopus tropicalis 58088 R-XTR-8849969 https://reactome.org/PathwayBrowser/#/R-XTR-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Xenopus tropicalis 58088 R-XTR-8870489 https://reactome.org/PathwayBrowser/#/R-XTR-8870489 PLEKHA4,(5,6) bind PI3P IEA Xenopus tropicalis 58088 R-XTR-8871376 https://reactome.org/PathwayBrowser/#/R-XTR-8871376 p-Y389,400-RUFY1 binds PI3P IEA Xenopus tropicalis 58092 R-BTA-200318 https://reactome.org/PathwayBrowser/#/R-BTA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Bos taurus 58092 R-BTA-200326 https://reactome.org/PathwayBrowser/#/R-BTA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Bos taurus 58092 R-CFA-200318 https://reactome.org/PathwayBrowser/#/R-CFA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Canis familiaris 58092 R-CFA-200326 https://reactome.org/PathwayBrowser/#/R-CFA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Canis familiaris 58092 R-DRE-200318 https://reactome.org/PathwayBrowser/#/R-DRE-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Danio rerio 58092 R-DRE-200326 https://reactome.org/PathwayBrowser/#/R-DRE-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Danio rerio 58092 R-GGA-200318 https://reactome.org/PathwayBrowser/#/R-GGA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Gallus gallus 58092 R-GGA-200326 https://reactome.org/PathwayBrowser/#/R-GGA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Gallus gallus 58092 R-HSA-200318 https://reactome.org/PathwayBrowser/#/R-HSA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] TAS Homo sapiens 58092 R-HSA-200326 https://reactome.org/PathwayBrowser/#/R-HSA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] TAS Homo sapiens 58092 R-HSA-71287 https://reactome.org/PathwayBrowser/#/R-HSA-71287 phosphocreatine + H2O => creatinine + orthophosphate TAS Homo sapiens 58092 R-MMU-200318 https://reactome.org/PathwayBrowser/#/R-MMU-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Mus musculus 58092 R-MMU-200326 https://reactome.org/PathwayBrowser/#/R-MMU-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Mus musculus 58092 R-RNO-200318 https://reactome.org/PathwayBrowser/#/R-RNO-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Rattus norvegicus 58092 R-RNO-200326 https://reactome.org/PathwayBrowser/#/R-RNO-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Rattus norvegicus 58092 R-SSC-200318 https://reactome.org/PathwayBrowser/#/R-SSC-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Sus scrofa 58092 R-SSC-200326 https://reactome.org/PathwayBrowser/#/R-SSC-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Sus scrofa 58092 R-XTR-200318 https://reactome.org/PathwayBrowser/#/R-XTR-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] IEA Xenopus tropicalis 58092 R-XTR-200326 https://reactome.org/PathwayBrowser/#/R-XTR-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Xenopus tropicalis 58095 R-BTA-1474146 https://reactome.org/PathwayBrowser/#/R-BTA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Bos taurus 58095 R-BTA-2160492 https://reactome.org/PathwayBrowser/#/R-BTA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Bos taurus 58095 R-BTA-352103 https://reactome.org/PathwayBrowser/#/R-BTA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Bos taurus 58095 R-BTA-352107 https://reactome.org/PathwayBrowser/#/R-BTA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Bos taurus 58095 R-BTA-352158 https://reactome.org/PathwayBrowser/#/R-BTA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Bos taurus 58095 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 58095 R-BTA-352232 https://reactome.org/PathwayBrowser/#/R-BTA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Bos taurus 58095 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 58095 R-BTA-5696365 https://reactome.org/PathwayBrowser/#/R-BTA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Bos taurus 58095 R-BTA-71118 https://reactome.org/PathwayBrowser/#/R-BTA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Bos taurus 58095 R-BTA-893593 https://reactome.org/PathwayBrowser/#/R-BTA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Bos taurus 58095 R-BTA-893596 https://reactome.org/PathwayBrowser/#/R-BTA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Bos taurus 58095 R-BTA-9673053 https://reactome.org/PathwayBrowser/#/R-BTA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Bos taurus 58095 R-BTA-9673054 https://reactome.org/PathwayBrowser/#/R-BTA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Bos taurus 58095 R-CEL-1474146 https://reactome.org/PathwayBrowser/#/R-CEL-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Caenorhabditis elegans 58095 R-CEL-71118 https://reactome.org/PathwayBrowser/#/R-CEL-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Caenorhabditis elegans 58095 R-CEL-893593 https://reactome.org/PathwayBrowser/#/R-CEL-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Caenorhabditis elegans 58095 R-CEL-893596 https://reactome.org/PathwayBrowser/#/R-CEL-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Caenorhabditis elegans 58095 R-CFA-1474146 https://reactome.org/PathwayBrowser/#/R-CFA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Canis familiaris 58095 R-CFA-2160492 https://reactome.org/PathwayBrowser/#/R-CFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Canis familiaris 58095 R-CFA-352103 https://reactome.org/PathwayBrowser/#/R-CFA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Canis familiaris 58095 R-CFA-352107 https://reactome.org/PathwayBrowser/#/R-CFA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Canis familiaris 58095 R-CFA-352158 https://reactome.org/PathwayBrowser/#/R-CFA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Canis familiaris 58095 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 58095 R-CFA-352232 https://reactome.org/PathwayBrowser/#/R-CFA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Canis familiaris 58095 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 58095 R-CFA-5696365 https://reactome.org/PathwayBrowser/#/R-CFA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Canis familiaris 58095 R-CFA-71118 https://reactome.org/PathwayBrowser/#/R-CFA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Canis familiaris 58095 R-CFA-893593 https://reactome.org/PathwayBrowser/#/R-CFA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Canis familiaris 58095 R-CFA-893596 https://reactome.org/PathwayBrowser/#/R-CFA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Canis familiaris 58095 R-CFA-9673053 https://reactome.org/PathwayBrowser/#/R-CFA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Canis familiaris 58095 R-CFA-9673054 https://reactome.org/PathwayBrowser/#/R-CFA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Canis familiaris 58095 R-DDI-1474146 https://reactome.org/PathwayBrowser/#/R-DDI-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Dictyostelium discoideum 58095 R-DDI-2160492 https://reactome.org/PathwayBrowser/#/R-DDI-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Dictyostelium discoideum 58095 R-DDI-352158 https://reactome.org/PathwayBrowser/#/R-DDI-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Dictyostelium discoideum 58095 R-DDI-71118 https://reactome.org/PathwayBrowser/#/R-DDI-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Dictyostelium discoideum 58095 R-DDI-893593 https://reactome.org/PathwayBrowser/#/R-DDI-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Dictyostelium discoideum 58095 R-DDI-893596 https://reactome.org/PathwayBrowser/#/R-DDI-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Dictyostelium discoideum 58095 R-DDI-9673053 https://reactome.org/PathwayBrowser/#/R-DDI-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Dictyostelium discoideum 58095 R-DDI-9673054 https://reactome.org/PathwayBrowser/#/R-DDI-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Dictyostelium discoideum 58095 R-DME-1474146 https://reactome.org/PathwayBrowser/#/R-DME-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Drosophila melanogaster 58095 R-DME-352158 https://reactome.org/PathwayBrowser/#/R-DME-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Drosophila melanogaster 58095 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 58095 R-DME-352232 https://reactome.org/PathwayBrowser/#/R-DME-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Drosophila melanogaster 58095 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 58095 R-DME-5696365 https://reactome.org/PathwayBrowser/#/R-DME-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Drosophila melanogaster 58095 R-DME-71118 https://reactome.org/PathwayBrowser/#/R-DME-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Drosophila melanogaster 58095 R-DME-893593 https://reactome.org/PathwayBrowser/#/R-DME-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Drosophila melanogaster 58095 R-DME-893596 https://reactome.org/PathwayBrowser/#/R-DME-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Drosophila melanogaster 58095 R-DRE-352103 https://reactome.org/PathwayBrowser/#/R-DRE-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Danio rerio 58095 R-DRE-352158 https://reactome.org/PathwayBrowser/#/R-DRE-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Danio rerio 58095 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 58095 R-DRE-5696365 https://reactome.org/PathwayBrowser/#/R-DRE-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Danio rerio 58095 R-DRE-71118 https://reactome.org/PathwayBrowser/#/R-DRE-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Danio rerio 58095 R-DRE-893593 https://reactome.org/PathwayBrowser/#/R-DRE-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Danio rerio 58095 R-DRE-893596 https://reactome.org/PathwayBrowser/#/R-DRE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Danio rerio 58095 R-DRE-9673053 https://reactome.org/PathwayBrowser/#/R-DRE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Danio rerio 58095 R-DRE-9673054 https://reactome.org/PathwayBrowser/#/R-DRE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Danio rerio 58095 R-GGA-1474146 https://reactome.org/PathwayBrowser/#/R-GGA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Gallus gallus 58095 R-GGA-352107 https://reactome.org/PathwayBrowser/#/R-GGA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Gallus gallus 58095 R-GGA-352158 https://reactome.org/PathwayBrowser/#/R-GGA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Gallus gallus 58095 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 58095 R-GGA-5696365 https://reactome.org/PathwayBrowser/#/R-GGA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Gallus gallus 58095 R-GGA-71118 https://reactome.org/PathwayBrowser/#/R-GGA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Gallus gallus 58095 R-GGA-893593 https://reactome.org/PathwayBrowser/#/R-GGA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Gallus gallus 58095 R-GGA-893596 https://reactome.org/PathwayBrowser/#/R-GGA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Gallus gallus 58095 R-GGA-9673053 https://reactome.org/PathwayBrowser/#/R-GGA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Gallus gallus 58095 R-GGA-9673054 https://reactome.org/PathwayBrowser/#/R-GGA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Gallus gallus 58095 R-HSA-1474146 https://reactome.org/PathwayBrowser/#/R-HSA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate TAS Homo sapiens 58095 R-HSA-2160492 https://reactome.org/PathwayBrowser/#/R-HSA-2160492 IL4I1:FAD oxidises L-Phe to kPPV TAS Homo sapiens 58095 R-HSA-352103 https://reactome.org/PathwayBrowser/#/R-HSA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids TAS Homo sapiens 58095 R-HSA-352107 https://reactome.org/PathwayBrowser/#/R-HSA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids TAS Homo sapiens 58095 R-HSA-352158 https://reactome.org/PathwayBrowser/#/R-HSA-352158 SLC16A10-mediated uptake of aromatic amino acids TAS Homo sapiens 58095 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 58095 R-HSA-352232 https://reactome.org/PathwayBrowser/#/R-HSA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol TAS Homo sapiens 58095 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 58095 R-HSA-379848 https://reactome.org/PathwayBrowser/#/R-HSA-379848 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 58095 R-HSA-380203 https://reactome.org/PathwayBrowser/#/R-HSA-380203 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate TAS Homo sapiens 58095 R-HSA-5649483 https://reactome.org/PathwayBrowser/#/R-HSA-5649483 Defective PAH does not hydroxylate L-Phe to L-Tyr TAS Homo sapiens 58095 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 58095 R-HSA-5696365 https://reactome.org/PathwayBrowser/#/R-HSA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe TAS Homo sapiens 58095 R-HSA-71118 https://reactome.org/PathwayBrowser/#/R-HSA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr TAS Homo sapiens 58095 R-HSA-893593 https://reactome.org/PathwayBrowser/#/R-HSA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine TAS Homo sapiens 58095 R-HSA-893596 https://reactome.org/PathwayBrowser/#/R-HSA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu TAS Homo sapiens 58095 R-HSA-9673053 https://reactome.org/PathwayBrowser/#/R-HSA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe TAS Homo sapiens 58095 R-HSA-9673054 https://reactome.org/PathwayBrowser/#/R-HSA-9673054 PM20D1 hydrolyzes oleoyl-phe TAS Homo sapiens 58095 R-MMU-1474146 https://reactome.org/PathwayBrowser/#/R-MMU-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Mus musculus 58095 R-MMU-2160492 https://reactome.org/PathwayBrowser/#/R-MMU-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Mus musculus 58095 R-MMU-352103 https://reactome.org/PathwayBrowser/#/R-MMU-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Mus musculus 58095 R-MMU-352107 https://reactome.org/PathwayBrowser/#/R-MMU-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Mus musculus 58095 R-MMU-352158 https://reactome.org/PathwayBrowser/#/R-MMU-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Mus musculus 58095 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 58095 R-MMU-352232 https://reactome.org/PathwayBrowser/#/R-MMU-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Mus musculus 58095 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 58095 R-MMU-5696365 https://reactome.org/PathwayBrowser/#/R-MMU-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Mus musculus 58095 R-MMU-71118 https://reactome.org/PathwayBrowser/#/R-MMU-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Mus musculus 58095 R-MMU-893593 https://reactome.org/PathwayBrowser/#/R-MMU-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Mus musculus 58095 R-MMU-893596 https://reactome.org/PathwayBrowser/#/R-MMU-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Mus musculus 58095 R-MMU-9673053 https://reactome.org/PathwayBrowser/#/R-MMU-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Mus musculus 58095 R-MMU-9673054 https://reactome.org/PathwayBrowser/#/R-MMU-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Mus musculus 58095 R-PFA-2160492 https://reactome.org/PathwayBrowser/#/R-PFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Plasmodium falciparum 58095 R-PFA-352158 https://reactome.org/PathwayBrowser/#/R-PFA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Plasmodium falciparum 58095 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 58095 R-RNO-1474146 https://reactome.org/PathwayBrowser/#/R-RNO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Rattus norvegicus 58095 R-RNO-2160492 https://reactome.org/PathwayBrowser/#/R-RNO-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Rattus norvegicus 58095 R-RNO-352103 https://reactome.org/PathwayBrowser/#/R-RNO-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Rattus norvegicus 58095 R-RNO-352107 https://reactome.org/PathwayBrowser/#/R-RNO-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Rattus norvegicus 58095 R-RNO-352158 https://reactome.org/PathwayBrowser/#/R-RNO-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Rattus norvegicus 58095 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 58095 R-RNO-352232 https://reactome.org/PathwayBrowser/#/R-RNO-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Rattus norvegicus 58095 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 58095 R-RNO-5696365 https://reactome.org/PathwayBrowser/#/R-RNO-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Rattus norvegicus 58095 R-RNO-71118 https://reactome.org/PathwayBrowser/#/R-RNO-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Rattus norvegicus 58095 R-RNO-893593 https://reactome.org/PathwayBrowser/#/R-RNO-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Rattus norvegicus 58095 R-RNO-893596 https://reactome.org/PathwayBrowser/#/R-RNO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Rattus norvegicus 58095 R-RNO-9673053 https://reactome.org/PathwayBrowser/#/R-RNO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Rattus norvegicus 58095 R-RNO-9673054 https://reactome.org/PathwayBrowser/#/R-RNO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Rattus norvegicus 58095 R-SCE-1474146 https://reactome.org/PathwayBrowser/#/R-SCE-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Saccharomyces cerevisiae 58095 R-SCE-352158 https://reactome.org/PathwayBrowser/#/R-SCE-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Saccharomyces cerevisiae 58095 R-SCE-893593 https://reactome.org/PathwayBrowser/#/R-SCE-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Saccharomyces cerevisiae 58095 R-SCE-893596 https://reactome.org/PathwayBrowser/#/R-SCE-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Saccharomyces cerevisiae 58095 R-SCE-9673053 https://reactome.org/PathwayBrowser/#/R-SCE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Saccharomyces cerevisiae 58095 R-SCE-9673054 https://reactome.org/PathwayBrowser/#/R-SCE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Saccharomyces cerevisiae 58095 R-SPO-1474146 https://reactome.org/PathwayBrowser/#/R-SPO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Schizosaccharomyces pombe 58095 R-SPO-893593 https://reactome.org/PathwayBrowser/#/R-SPO-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Schizosaccharomyces pombe 58095 R-SPO-893596 https://reactome.org/PathwayBrowser/#/R-SPO-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Schizosaccharomyces pombe 58095 R-SPO-9673053 https://reactome.org/PathwayBrowser/#/R-SPO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Schizosaccharomyces pombe 58095 R-SPO-9673054 https://reactome.org/PathwayBrowser/#/R-SPO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Schizosaccharomyces pombe 58095 R-SSC-1474146 https://reactome.org/PathwayBrowser/#/R-SSC-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Sus scrofa 58095 R-SSC-2160492 https://reactome.org/PathwayBrowser/#/R-SSC-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Sus scrofa 58095 R-SSC-352103 https://reactome.org/PathwayBrowser/#/R-SSC-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Sus scrofa 58095 R-SSC-352107 https://reactome.org/PathwayBrowser/#/R-SSC-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Sus scrofa 58095 R-SSC-352158 https://reactome.org/PathwayBrowser/#/R-SSC-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Sus scrofa 58095 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 58095 R-SSC-352232 https://reactome.org/PathwayBrowser/#/R-SSC-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Sus scrofa 58095 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 58095 R-SSC-5696365 https://reactome.org/PathwayBrowser/#/R-SSC-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe IEA Sus scrofa 58095 R-SSC-71118 https://reactome.org/PathwayBrowser/#/R-SSC-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Sus scrofa 58095 R-SSC-893593 https://reactome.org/PathwayBrowser/#/R-SSC-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Sus scrofa 58095 R-SSC-893596 https://reactome.org/PathwayBrowser/#/R-SSC-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Sus scrofa 58095 R-SSC-9673053 https://reactome.org/PathwayBrowser/#/R-SSC-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Sus scrofa 58095 R-SSC-9673054 https://reactome.org/PathwayBrowser/#/R-SSC-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Sus scrofa 58095 R-XTR-1474146 https://reactome.org/PathwayBrowser/#/R-XTR-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Xenopus tropicalis 58095 R-XTR-2160492 https://reactome.org/PathwayBrowser/#/R-XTR-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Xenopus tropicalis 58095 R-XTR-352103 https://reactome.org/PathwayBrowser/#/R-XTR-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids IEA Xenopus tropicalis 58095 R-XTR-352107 https://reactome.org/PathwayBrowser/#/R-XTR-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids IEA Xenopus tropicalis 58095 R-XTR-352158 https://reactome.org/PathwayBrowser/#/R-XTR-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Xenopus tropicalis 58095 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 58095 R-XTR-352232 https://reactome.org/PathwayBrowser/#/R-XTR-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Xenopus tropicalis 58095 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 58095 R-XTR-71118 https://reactome.org/PathwayBrowser/#/R-XTR-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Xenopus tropicalis 58095 R-XTR-893593 https://reactome.org/PathwayBrowser/#/R-XTR-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine IEA Xenopus tropicalis 58095 R-XTR-893596 https://reactome.org/PathwayBrowser/#/R-XTR-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu IEA Xenopus tropicalis 58095 R-XTR-9673053 https://reactome.org/PathwayBrowser/#/R-XTR-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Xenopus tropicalis 58095 R-XTR-9673054 https://reactome.org/PathwayBrowser/#/R-XTR-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Xenopus tropicalis 58100 R-BTA-71241 https://reactome.org/PathwayBrowser/#/R-BTA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Bos taurus 58100 R-CEL-71241 https://reactome.org/PathwayBrowser/#/R-CEL-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Caenorhabditis elegans 58100 R-CFA-71241 https://reactome.org/PathwayBrowser/#/R-CFA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Canis familiaris 58100 R-DME-71241 https://reactome.org/PathwayBrowser/#/R-DME-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Drosophila melanogaster 58100 R-GGA-71241 https://reactome.org/PathwayBrowser/#/R-GGA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Gallus gallus 58100 R-HSA-71241 https://reactome.org/PathwayBrowser/#/R-HSA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA TAS Homo sapiens 58100 R-MMU-71241 https://reactome.org/PathwayBrowser/#/R-MMU-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Mus musculus 58100 R-RNO-71241 https://reactome.org/PathwayBrowser/#/R-RNO-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Rattus norvegicus 58100 R-SSC-71241 https://reactome.org/PathwayBrowser/#/R-SSC-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Sus scrofa 58100 R-XTR-71241 https://reactome.org/PathwayBrowser/#/R-XTR-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Xenopus tropicalis 58101 R-BTA-141351 https://reactome.org/PathwayBrowser/#/R-BTA-141351 PAOX:FAD oxidises NASPN to SPM IEA Bos taurus 58101 R-BTA-351207 https://reactome.org/PathwayBrowser/#/R-BTA-351207 Spermine => N-acetylated spermine IEA Bos taurus 58101 R-CEL-141351 https://reactome.org/PathwayBrowser/#/R-CEL-141351 PAOX:FAD oxidises NASPN to SPM IEA Caenorhabditis elegans 58101 R-CEL-351207 https://reactome.org/PathwayBrowser/#/R-CEL-351207 Spermine => N-acetylated spermine IEA Caenorhabditis elegans 58101 R-CFA-141351 https://reactome.org/PathwayBrowser/#/R-CFA-141351 PAOX:FAD oxidises NASPN to SPM IEA Canis familiaris 58101 R-CFA-351207 https://reactome.org/PathwayBrowser/#/R-CFA-351207 Spermine => N-acetylated spermine IEA Canis familiaris 58101 R-DDI-351207 https://reactome.org/PathwayBrowser/#/R-DDI-351207 Spermine => N-acetylated spermine IEA Dictyostelium discoideum 58101 R-DME-141351 https://reactome.org/PathwayBrowser/#/R-DME-141351 PAOX:FAD oxidises NASPN to SPM IEA Drosophila melanogaster 58101 R-DME-351207 https://reactome.org/PathwayBrowser/#/R-DME-351207 Spermine => N-acetylated spermine IEA Drosophila melanogaster 58101 R-DRE-141351 https://reactome.org/PathwayBrowser/#/R-DRE-141351 PAOX:FAD oxidises NASPN to SPM IEA Danio rerio 58101 R-DRE-351207 https://reactome.org/PathwayBrowser/#/R-DRE-351207 Spermine => N-acetylated spermine IEA Danio rerio 58101 R-GGA-141351 https://reactome.org/PathwayBrowser/#/R-GGA-141351 PAOX:FAD oxidises NASPN to SPM IEA Gallus gallus 58101 R-GGA-351207 https://reactome.org/PathwayBrowser/#/R-GGA-351207 Spermine => N-acetylated spermine IEA Gallus gallus 58101 R-HSA-141351 https://reactome.org/PathwayBrowser/#/R-HSA-141351 PAOX:FAD oxidises NASPN to SPM TAS Homo sapiens 58101 R-HSA-351207 https://reactome.org/PathwayBrowser/#/R-HSA-351207 Spermine => N-acetylated spermine TAS Homo sapiens 58101 R-HSA-351229 https://reactome.org/PathwayBrowser/#/R-HSA-351229 N-acetylated spermine (cytosol)=>N-acetylated spermine (peroxisomal) TAS Homo sapiens 58101 R-MMU-141351 https://reactome.org/PathwayBrowser/#/R-MMU-141351 PAOX:FAD oxidises NASPN to SPM IEA Mus musculus 58101 R-MMU-351207 https://reactome.org/PathwayBrowser/#/R-MMU-351207 Spermine => N-acetylated spermine IEA Mus musculus 58101 R-RNO-141351 https://reactome.org/PathwayBrowser/#/R-RNO-141351 PAOX:FAD oxidises NASPN to SPM IEA Rattus norvegicus 58101 R-RNO-351207 https://reactome.org/PathwayBrowser/#/R-RNO-351207 Spermine => N-acetylated spermine IEA Rattus norvegicus 58101 R-SCE-351207 https://reactome.org/PathwayBrowser/#/R-SCE-351207 Spermine => N-acetylated spermine IEA Saccharomyces cerevisiae 58101 R-SPO-351207 https://reactome.org/PathwayBrowser/#/R-SPO-351207 Spermine => N-acetylated spermine IEA Schizosaccharomyces pombe 58101 R-SSC-141351 https://reactome.org/PathwayBrowser/#/R-SSC-141351 PAOX:FAD oxidises NASPN to SPM IEA Sus scrofa 58101 R-SSC-351207 https://reactome.org/PathwayBrowser/#/R-SSC-351207 Spermine => N-acetylated spermine IEA Sus scrofa 58101 R-XTR-351207 https://reactome.org/PathwayBrowser/#/R-XTR-351207 Spermine => N-acetylated spermine IEA Xenopus tropicalis 58115 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 58115 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 58115 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 58115 R-BTA-110133 https://reactome.org/PathwayBrowser/#/R-BTA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Bos taurus 58115 R-BTA-111285 https://reactome.org/PathwayBrowser/#/R-BTA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Bos taurus 58115 R-BTA-111524 https://reactome.org/PathwayBrowser/#/R-BTA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Bos taurus 58115 R-BTA-174441 https://reactome.org/PathwayBrowser/#/R-BTA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Bos taurus 58115 R-BTA-4086392 https://reactome.org/PathwayBrowser/#/R-BTA-4086392 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 58115 R-BTA-418456 https://reactome.org/PathwayBrowser/#/R-BTA-418456 cGMP is degraded by PDEs IEA Bos taurus 58115 R-BTA-430028 https://reactome.org/PathwayBrowser/#/R-BTA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Bos taurus 58115 R-BTA-514604 https://reactome.org/PathwayBrowser/#/R-BTA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Bos taurus 58115 R-BTA-5696197 https://reactome.org/PathwayBrowser/#/R-BTA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Bos taurus 58115 R-BTA-69144 https://reactome.org/PathwayBrowser/#/R-BTA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Bos taurus 58115 R-BTA-73788 https://reactome.org/PathwayBrowser/#/R-BTA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Bos taurus 58115 R-BTA-73792 https://reactome.org/PathwayBrowser/#/R-BTA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Bos taurus 58115 R-BTA-74059 https://reactome.org/PathwayBrowser/#/R-BTA-74059 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 58115 R-BTA-74215 https://reactome.org/PathwayBrowser/#/R-BTA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Bos taurus 58115 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 58115 R-BTA-744230 https://reactome.org/PathwayBrowser/#/R-BTA-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Bos taurus 58115 R-BTA-77081 https://reactome.org/PathwayBrowser/#/R-BTA-77081 Formation of the CE:GMP intermediate complex IEA Bos taurus 58115 R-BTA-77083 https://reactome.org/PathwayBrowser/#/R-BTA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Bos taurus 58115 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 58115 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 58115 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 58115 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 58115 R-BTA-9717206 https://reactome.org/PathwayBrowser/#/R-BTA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Bos taurus 58115 R-CEL-110133 https://reactome.org/PathwayBrowser/#/R-CEL-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Caenorhabditis elegans 58115 R-CEL-111285 https://reactome.org/PathwayBrowser/#/R-CEL-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Caenorhabditis elegans 58115 R-CEL-111524 https://reactome.org/PathwayBrowser/#/R-CEL-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Caenorhabditis elegans 58115 R-CEL-418456 https://reactome.org/PathwayBrowser/#/R-CEL-418456 cGMP is degraded by PDEs IEA Caenorhabditis elegans 58115 R-CEL-430028 https://reactome.org/PathwayBrowser/#/R-CEL-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Caenorhabditis elegans 58115 R-CEL-514604 https://reactome.org/PathwayBrowser/#/R-CEL-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Caenorhabditis elegans 58115 R-CEL-5696197 https://reactome.org/PathwayBrowser/#/R-CEL-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Caenorhabditis elegans 58115 R-CEL-73788 https://reactome.org/PathwayBrowser/#/R-CEL-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Caenorhabditis elegans 58115 R-CEL-73792 https://reactome.org/PathwayBrowser/#/R-CEL-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Caenorhabditis elegans 58115 R-CEL-74215 https://reactome.org/PathwayBrowser/#/R-CEL-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Caenorhabditis elegans 58115 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 58115 R-CEL-744230 https://reactome.org/PathwayBrowser/#/R-CEL-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Caenorhabditis elegans 58115 R-CEL-77081 https://reactome.org/PathwayBrowser/#/R-CEL-77081 Formation of the CE:GMP intermediate complex IEA Caenorhabditis elegans 58115 R-CEL-77083 https://reactome.org/PathwayBrowser/#/R-CEL-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Caenorhabditis elegans 58115 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58115 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58115 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58115 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 58115 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 58115 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 58115 R-CFA-110133 https://reactome.org/PathwayBrowser/#/R-CFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Canis familiaris 58115 R-CFA-111285 https://reactome.org/PathwayBrowser/#/R-CFA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Canis familiaris 58115 R-CFA-111524 https://reactome.org/PathwayBrowser/#/R-CFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Canis familiaris 58115 R-CFA-174441 https://reactome.org/PathwayBrowser/#/R-CFA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Canis familiaris 58115 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 58115 R-CFA-4086392 https://reactome.org/PathwayBrowser/#/R-CFA-4086392 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 58115 R-CFA-418456 https://reactome.org/PathwayBrowser/#/R-CFA-418456 cGMP is degraded by PDEs IEA Canis familiaris 58115 R-CFA-430028 https://reactome.org/PathwayBrowser/#/R-CFA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Canis familiaris 58115 R-CFA-514604 https://reactome.org/PathwayBrowser/#/R-CFA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Canis familiaris 58115 R-CFA-5696197 https://reactome.org/PathwayBrowser/#/R-CFA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Canis familiaris 58115 R-CFA-69144 https://reactome.org/PathwayBrowser/#/R-CFA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Canis familiaris 58115 R-CFA-73788 https://reactome.org/PathwayBrowser/#/R-CFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Canis familiaris 58115 R-CFA-73792 https://reactome.org/PathwayBrowser/#/R-CFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Canis familiaris 58115 R-CFA-74059 https://reactome.org/PathwayBrowser/#/R-CFA-74059 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 58115 R-CFA-74215 https://reactome.org/PathwayBrowser/#/R-CFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Canis familiaris 58115 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 58115 R-CFA-744230 https://reactome.org/PathwayBrowser/#/R-CFA-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Canis familiaris 58115 R-CFA-77081 https://reactome.org/PathwayBrowser/#/R-CFA-77081 Formation of the CE:GMP intermediate complex IEA Canis familiaris 58115 R-CFA-77083 https://reactome.org/PathwayBrowser/#/R-CFA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Canis familiaris 58115 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58115 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58115 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58115 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58115 R-CFA-9717206 https://reactome.org/PathwayBrowser/#/R-CFA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Canis familiaris 58115 R-DDI-110133 https://reactome.org/PathwayBrowser/#/R-DDI-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Dictyostelium discoideum 58115 R-DDI-111524 https://reactome.org/PathwayBrowser/#/R-DDI-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Dictyostelium discoideum 58115 R-DDI-418456 https://reactome.org/PathwayBrowser/#/R-DDI-418456 cGMP is degraded by PDEs IEA Dictyostelium discoideum 58115 R-DDI-430028 https://reactome.org/PathwayBrowser/#/R-DDI-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Dictyostelium discoideum 58115 R-DDI-73788 https://reactome.org/PathwayBrowser/#/R-DDI-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Dictyostelium discoideum 58115 R-DDI-73792 https://reactome.org/PathwayBrowser/#/R-DDI-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Dictyostelium discoideum 58115 R-DDI-74215 https://reactome.org/PathwayBrowser/#/R-DDI-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Dictyostelium discoideum 58115 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 58115 R-DDI-744230 https://reactome.org/PathwayBrowser/#/R-DDI-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Dictyostelium discoideum 58115 R-DDI-77081 https://reactome.org/PathwayBrowser/#/R-DDI-77081 Formation of the CE:GMP intermediate complex IEA Dictyostelium discoideum 58115 R-DDI-77083 https://reactome.org/PathwayBrowser/#/R-DDI-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Dictyostelium discoideum 58115 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 58115 R-DME-110133 https://reactome.org/PathwayBrowser/#/R-DME-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Drosophila melanogaster 58115 R-DME-111285 https://reactome.org/PathwayBrowser/#/R-DME-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Drosophila melanogaster 58115 R-DME-111524 https://reactome.org/PathwayBrowser/#/R-DME-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Drosophila melanogaster 58115 R-DME-418456 https://reactome.org/PathwayBrowser/#/R-DME-418456 cGMP is degraded by PDEs IEA Drosophila melanogaster 58115 R-DME-430028 https://reactome.org/PathwayBrowser/#/R-DME-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Drosophila melanogaster 58115 R-DME-5696197 https://reactome.org/PathwayBrowser/#/R-DME-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Drosophila melanogaster 58115 R-DME-69144 https://reactome.org/PathwayBrowser/#/R-DME-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Drosophila melanogaster 58115 R-DME-73788 https://reactome.org/PathwayBrowser/#/R-DME-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Drosophila melanogaster 58115 R-DME-73792 https://reactome.org/PathwayBrowser/#/R-DME-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Drosophila melanogaster 58115 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 58115 R-DME-744230 https://reactome.org/PathwayBrowser/#/R-DME-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Drosophila melanogaster 58115 R-DME-77081 https://reactome.org/PathwayBrowser/#/R-DME-77081 Formation of the CE:GMP intermediate complex IEA Drosophila melanogaster 58115 R-DME-77083 https://reactome.org/PathwayBrowser/#/R-DME-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Drosophila melanogaster 58115 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 58115 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 58115 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 58115 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 58115 R-DRE-110133 https://reactome.org/PathwayBrowser/#/R-DRE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Danio rerio 58115 R-DRE-111285 https://reactome.org/PathwayBrowser/#/R-DRE-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Danio rerio 58115 R-DRE-111524 https://reactome.org/PathwayBrowser/#/R-DRE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Danio rerio 58115 R-DRE-514604 https://reactome.org/PathwayBrowser/#/R-DRE-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Danio rerio 58115 R-DRE-5696197 https://reactome.org/PathwayBrowser/#/R-DRE-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Danio rerio 58115 R-DRE-73788 https://reactome.org/PathwayBrowser/#/R-DRE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Danio rerio 58115 R-DRE-74215 https://reactome.org/PathwayBrowser/#/R-DRE-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Danio rerio 58115 R-DRE-77081 https://reactome.org/PathwayBrowser/#/R-DRE-77081 Formation of the CE:GMP intermediate complex IEA Danio rerio 58115 R-DRE-77083 https://reactome.org/PathwayBrowser/#/R-DRE-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Danio rerio 58115 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 58115 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 58115 R-DRE-9717206 https://reactome.org/PathwayBrowser/#/R-DRE-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Danio rerio 58115 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 58115 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 58115 R-GGA-110133 https://reactome.org/PathwayBrowser/#/R-GGA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Gallus gallus 58115 R-GGA-111285 https://reactome.org/PathwayBrowser/#/R-GGA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Gallus gallus 58115 R-GGA-111524 https://reactome.org/PathwayBrowser/#/R-GGA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Gallus gallus 58115 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 58115 R-GGA-4086392 https://reactome.org/PathwayBrowser/#/R-GGA-4086392 PDE6 hydrolyses cGMP to GMP IEA Gallus gallus 58115 R-GGA-418456 https://reactome.org/PathwayBrowser/#/R-GGA-418456 cGMP is degraded by PDEs IEA Gallus gallus 58115 R-GGA-420906 https://reactome.org/PathwayBrowser/#/R-GGA-420906 Formation of PPAT tetramers TAS Gallus gallus 58115 R-GGA-420911 https://reactome.org/PathwayBrowser/#/R-GGA-420911 Formation of PPAT dimers IEA Gallus gallus 58115 R-GGA-421218 https://reactome.org/PathwayBrowser/#/R-GGA-421218 xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate IEA Gallus gallus 58115 R-GGA-430028 https://reactome.org/PathwayBrowser/#/R-GGA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Gallus gallus 58115 R-GGA-514604 https://reactome.org/PathwayBrowser/#/R-GGA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Gallus gallus 58115 R-GGA-5696197 https://reactome.org/PathwayBrowser/#/R-GGA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Gallus gallus 58115 R-GGA-73788 https://reactome.org/PathwayBrowser/#/R-GGA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Gallus gallus 58115 R-GGA-73792 https://reactome.org/PathwayBrowser/#/R-GGA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Gallus gallus 58115 R-GGA-74215 https://reactome.org/PathwayBrowser/#/R-GGA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Gallus gallus 58115 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 58115 R-GGA-744230 https://reactome.org/PathwayBrowser/#/R-GGA-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Gallus gallus 58115 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus 58115 R-GGA-77083 https://reactome.org/PathwayBrowser/#/R-GGA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Gallus gallus 58115 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58115 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58115 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58115 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58115 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 58115 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 58115 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 58115 R-HSA-110133 https://reactome.org/PathwayBrowser/#/R-HSA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) TAS Homo sapiens 58115 R-HSA-111285 https://reactome.org/PathwayBrowser/#/R-HSA-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer TAS Homo sapiens 58115 R-HSA-111524 https://reactome.org/PathwayBrowser/#/R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] TAS Homo sapiens 58115 R-HSA-174441 https://reactome.org/PathwayBrowser/#/R-HSA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand TAS Homo sapiens 58115 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 58115 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 58115 R-HSA-4086392 https://reactome.org/PathwayBrowser/#/R-HSA-4086392 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 58115 R-HSA-418456 https://reactome.org/PathwayBrowser/#/R-HSA-418456 cGMP is degraded by PDEs TAS Homo sapiens 58115 R-HSA-429845 https://reactome.org/PathwayBrowser/#/R-HSA-429845 5' to 3' exoribonuclease hydrolyzes decapped mRNA IEA Homo sapiens 58115 R-HSA-430028 https://reactome.org/PathwayBrowser/#/R-HSA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion TAS Homo sapiens 58115 R-HSA-514604 https://reactome.org/PathwayBrowser/#/R-HSA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) TAS Homo sapiens 58115 R-HSA-5696197 https://reactome.org/PathwayBrowser/#/R-HSA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP TAS Homo sapiens 58115 R-HSA-69144 https://reactome.org/PathwayBrowser/#/R-HSA-69144 Removal of RNA primer and dissociation of RPA and Dna2 TAS Homo sapiens 58115 R-HSA-73788 https://reactome.org/PathwayBrowser/#/R-HSA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) TAS Homo sapiens 58115 R-HSA-73792 https://reactome.org/PathwayBrowser/#/R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate TAS Homo sapiens 58115 R-HSA-74059 https://reactome.org/PathwayBrowser/#/R-HSA-74059 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 58115 R-HSA-74215 https://reactome.org/PathwayBrowser/#/R-HSA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 58115 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 58115 R-HSA-744230 https://reactome.org/PathwayBrowser/#/R-HSA-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP TAS Homo sapiens 58115 R-HSA-77081 https://reactome.org/PathwayBrowser/#/R-HSA-77081 Formation of the CE:GMP intermediate complex TAS Homo sapiens 58115 R-HSA-77083 https://reactome.org/PathwayBrowser/#/R-HSA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA TAS Homo sapiens 58115 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58115 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58115 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58115 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58115 R-HSA-9717182 https://reactome.org/PathwayBrowser/#/R-HSA-9717182 L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP and GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 58115 R-HSA-9717202 https://reactome.org/PathwayBrowser/#/R-HSA-9717202 GNAT3 exchanges GDP for GTP in L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 58115 R-HSA-9717206 https://reactome.org/PathwayBrowser/#/R-HSA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) TAS Homo sapiens 58115 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 58115 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 58115 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 58115 R-MMU-110133 https://reactome.org/PathwayBrowser/#/R-MMU-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Mus musculus 58115 R-MMU-111285 https://reactome.org/PathwayBrowser/#/R-MMU-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Mus musculus 58115 R-MMU-111519 https://reactome.org/PathwayBrowser/#/R-MMU-111519 inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate TAS Mus musculus 58115 R-MMU-111524 https://reactome.org/PathwayBrowser/#/R-MMU-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Mus musculus 58115 R-MMU-174441 https://reactome.org/PathwayBrowser/#/R-MMU-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Mus musculus 58115 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 58115 R-MMU-4086392 https://reactome.org/PathwayBrowser/#/R-MMU-4086392 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 58115 R-MMU-418456 https://reactome.org/PathwayBrowser/#/R-MMU-418456 cGMP is degraded by PDEs IEA Mus musculus 58115 R-MMU-430028 https://reactome.org/PathwayBrowser/#/R-MMU-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Mus musculus 58115 R-MMU-514604 https://reactome.org/PathwayBrowser/#/R-MMU-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Mus musculus 58115 R-MMU-5696197 https://reactome.org/PathwayBrowser/#/R-MMU-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Mus musculus 58115 R-MMU-69144 https://reactome.org/PathwayBrowser/#/R-MMU-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Mus musculus 58115 R-MMU-73788 https://reactome.org/PathwayBrowser/#/R-MMU-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Mus musculus 58115 R-MMU-73792 https://reactome.org/PathwayBrowser/#/R-MMU-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Mus musculus 58115 R-MMU-74059 https://reactome.org/PathwayBrowser/#/R-MMU-74059 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 58115 R-MMU-74215 https://reactome.org/PathwayBrowser/#/R-MMU-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Mus musculus 58115 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 58115 R-MMU-744230 https://reactome.org/PathwayBrowser/#/R-MMU-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Mus musculus 58115 R-MMU-77081 https://reactome.org/PathwayBrowser/#/R-MMU-77081 Formation of the CE:GMP intermediate complex IEA Mus musculus 58115 R-MMU-77083 https://reactome.org/PathwayBrowser/#/R-MMU-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Mus musculus 58115 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 58115 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 58115 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 58115 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 58115 R-MMU-9717206 https://reactome.org/PathwayBrowser/#/R-MMU-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Mus musculus 58115 R-PFA-110133 https://reactome.org/PathwayBrowser/#/R-PFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Plasmodium falciparum 58115 R-PFA-111524 https://reactome.org/PathwayBrowser/#/R-PFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Plasmodium falciparum 58115 R-PFA-418456 https://reactome.org/PathwayBrowser/#/R-PFA-418456 cGMP is degraded by PDEs IEA Plasmodium falciparum 58115 R-PFA-5696197 https://reactome.org/PathwayBrowser/#/R-PFA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Plasmodium falciparum 58115 R-PFA-73788 https://reactome.org/PathwayBrowser/#/R-PFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Plasmodium falciparum 58115 R-PFA-73792 https://reactome.org/PathwayBrowser/#/R-PFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Plasmodium falciparum 58115 R-PFA-74215 https://reactome.org/PathwayBrowser/#/R-PFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Plasmodium falciparum 58115 R-PFA-77081 https://reactome.org/PathwayBrowser/#/R-PFA-77081 Formation of the CE:GMP intermediate complex IEA Plasmodium falciparum 58115 R-PFA-77083 https://reactome.org/PathwayBrowser/#/R-PFA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Plasmodium falciparum 58115 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58115 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58115 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58115 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 58115 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 58115 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 58115 R-RNO-110133 https://reactome.org/PathwayBrowser/#/R-RNO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Rattus norvegicus 58115 R-RNO-111285 https://reactome.org/PathwayBrowser/#/R-RNO-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Rattus norvegicus 58115 R-RNO-111524 https://reactome.org/PathwayBrowser/#/R-RNO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Rattus norvegicus 58115 R-RNO-174441 https://reactome.org/PathwayBrowser/#/R-RNO-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Rattus norvegicus 58115 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 58115 R-RNO-4086392 https://reactome.org/PathwayBrowser/#/R-RNO-4086392 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 58115 R-RNO-418456 https://reactome.org/PathwayBrowser/#/R-RNO-418456 cGMP is degraded by PDEs IEA Rattus norvegicus 58115 R-RNO-430028 https://reactome.org/PathwayBrowser/#/R-RNO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Rattus norvegicus 58115 R-RNO-514604 https://reactome.org/PathwayBrowser/#/R-RNO-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Rattus norvegicus 58115 R-RNO-5696197 https://reactome.org/PathwayBrowser/#/R-RNO-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Rattus norvegicus 58115 R-RNO-69144 https://reactome.org/PathwayBrowser/#/R-RNO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Rattus norvegicus 58115 R-RNO-73788 https://reactome.org/PathwayBrowser/#/R-RNO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Rattus norvegicus 58115 R-RNO-73792 https://reactome.org/PathwayBrowser/#/R-RNO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Rattus norvegicus 58115 R-RNO-74059 https://reactome.org/PathwayBrowser/#/R-RNO-74059 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 58115 R-RNO-74215 https://reactome.org/PathwayBrowser/#/R-RNO-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Rattus norvegicus 58115 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 58115 R-RNO-744230 https://reactome.org/PathwayBrowser/#/R-RNO-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Rattus norvegicus 58115 R-RNO-77081 https://reactome.org/PathwayBrowser/#/R-RNO-77081 Formation of the CE:GMP intermediate complex IEA Rattus norvegicus 58115 R-RNO-77083 https://reactome.org/PathwayBrowser/#/R-RNO-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Rattus norvegicus 58115 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58115 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58115 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58115 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58115 R-RNO-9717206 https://reactome.org/PathwayBrowser/#/R-RNO-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Rattus norvegicus 58115 R-SCE-110133 https://reactome.org/PathwayBrowser/#/R-SCE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Saccharomyces cerevisiae 58115 R-SCE-111524 https://reactome.org/PathwayBrowser/#/R-SCE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Saccharomyces cerevisiae 58115 R-SCE-418456 https://reactome.org/PathwayBrowser/#/R-SCE-418456 cGMP is degraded by PDEs IEA Saccharomyces cerevisiae 58115 R-SCE-429913 https://reactome.org/PathwayBrowser/#/R-SCE-429913 5' to 3' Exoribonuclease Digestion of Decapped mRNA (yeast) TAS Saccharomyces cerevisiae 58115 R-SCE-430028 https://reactome.org/PathwayBrowser/#/R-SCE-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Saccharomyces cerevisiae 58115 R-SCE-73788 https://reactome.org/PathwayBrowser/#/R-SCE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Saccharomyces cerevisiae 58115 R-SCE-73792 https://reactome.org/PathwayBrowser/#/R-SCE-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Saccharomyces cerevisiae 58115 R-SCE-77081 https://reactome.org/PathwayBrowser/#/R-SCE-77081 Formation of the CE:GMP intermediate complex IEA Saccharomyces cerevisiae 58115 R-SCE-77083 https://reactome.org/PathwayBrowser/#/R-SCE-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Saccharomyces cerevisiae 58115 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58115 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58115 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58115 R-SPO-110133 https://reactome.org/PathwayBrowser/#/R-SPO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Schizosaccharomyces pombe 58115 R-SPO-111524 https://reactome.org/PathwayBrowser/#/R-SPO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Schizosaccharomyces pombe 58115 R-SPO-430028 https://reactome.org/PathwayBrowser/#/R-SPO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Schizosaccharomyces pombe 58115 R-SPO-69144 https://reactome.org/PathwayBrowser/#/R-SPO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Schizosaccharomyces pombe 58115 R-SPO-73788 https://reactome.org/PathwayBrowser/#/R-SPO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Schizosaccharomyces pombe 58115 R-SPO-73792 https://reactome.org/PathwayBrowser/#/R-SPO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Schizosaccharomyces pombe 58115 R-SPO-77081 https://reactome.org/PathwayBrowser/#/R-SPO-77081 Formation of the CE:GMP intermediate complex IEA Schizosaccharomyces pombe 58115 R-SPO-77083 https://reactome.org/PathwayBrowser/#/R-SPO-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Schizosaccharomyces pombe 58115 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58115 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58115 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58115 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 58115 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 58115 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 58115 R-SSC-110133 https://reactome.org/PathwayBrowser/#/R-SSC-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Sus scrofa 58115 R-SSC-111285 https://reactome.org/PathwayBrowser/#/R-SSC-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Sus scrofa 58115 R-SSC-111524 https://reactome.org/PathwayBrowser/#/R-SSC-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Sus scrofa 58115 R-SSC-174441 https://reactome.org/PathwayBrowser/#/R-SSC-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Sus scrofa 58115 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 58115 R-SSC-4086392 https://reactome.org/PathwayBrowser/#/R-SSC-4086392 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 58115 R-SSC-418456 https://reactome.org/PathwayBrowser/#/R-SSC-418456 cGMP is degraded by PDEs IEA Sus scrofa 58115 R-SSC-430028 https://reactome.org/PathwayBrowser/#/R-SSC-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Sus scrofa 58115 R-SSC-514604 https://reactome.org/PathwayBrowser/#/R-SSC-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Sus scrofa 58115 R-SSC-5696197 https://reactome.org/PathwayBrowser/#/R-SSC-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Sus scrofa 58115 R-SSC-69144 https://reactome.org/PathwayBrowser/#/R-SSC-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Sus scrofa 58115 R-SSC-73788 https://reactome.org/PathwayBrowser/#/R-SSC-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Sus scrofa 58115 R-SSC-73792 https://reactome.org/PathwayBrowser/#/R-SSC-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Sus scrofa 58115 R-SSC-74059 https://reactome.org/PathwayBrowser/#/R-SSC-74059 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 58115 R-SSC-74215 https://reactome.org/PathwayBrowser/#/R-SSC-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Sus scrofa 58115 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 58115 R-SSC-744230 https://reactome.org/PathwayBrowser/#/R-SSC-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Sus scrofa 58115 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa 58115 R-SSC-77083 https://reactome.org/PathwayBrowser/#/R-SSC-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Sus scrofa 58115 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58115 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58115 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58115 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58115 R-SSC-9717206 https://reactome.org/PathwayBrowser/#/R-SSC-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Sus scrofa 58115 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 58115 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 58115 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 58115 R-XTR-110133 https://reactome.org/PathwayBrowser/#/R-XTR-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Xenopus tropicalis 58115 R-XTR-111285 https://reactome.org/PathwayBrowser/#/R-XTR-111285 Formation of phosphoribosyl pyrophosphate amidotransferase tetramer IEA Xenopus tropicalis 58115 R-XTR-111524 https://reactome.org/PathwayBrowser/#/R-XTR-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Xenopus tropicalis 58115 R-XTR-4086392 https://reactome.org/PathwayBrowser/#/R-XTR-4086392 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 58115 R-XTR-418456 https://reactome.org/PathwayBrowser/#/R-XTR-418456 cGMP is degraded by PDEs IEA Xenopus tropicalis 58115 R-XTR-430028 https://reactome.org/PathwayBrowser/#/R-XTR-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Xenopus tropicalis 58115 R-XTR-514604 https://reactome.org/PathwayBrowser/#/R-XTR-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Xenopus tropicalis 58115 R-XTR-5696197 https://reactome.org/PathwayBrowser/#/R-XTR-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Xenopus tropicalis 58115 R-XTR-73788 https://reactome.org/PathwayBrowser/#/R-XTR-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Xenopus tropicalis 58115 R-XTR-73792 https://reactome.org/PathwayBrowser/#/R-XTR-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Xenopus tropicalis 58115 R-XTR-74059 https://reactome.org/PathwayBrowser/#/R-XTR-74059 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 58115 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 58115 R-XTR-744230 https://reactome.org/PathwayBrowser/#/R-XTR-744230 SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP IEA Xenopus tropicalis 58115 R-XTR-77081 https://reactome.org/PathwayBrowser/#/R-XTR-77081 Formation of the CE:GMP intermediate complex IEA Xenopus tropicalis 58115 R-XTR-77083 https://reactome.org/PathwayBrowser/#/R-XTR-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Xenopus tropicalis 58115 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58115 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58115 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58121 R-BTA-177784 https://reactome.org/PathwayBrowser/#/R-BTA-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Bos taurus 58121 R-BTA-199803 https://reactome.org/PathwayBrowser/#/R-BTA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Bos taurus 58121 R-BTA-71299 https://reactome.org/PathwayBrowser/#/R-BTA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Bos taurus 58121 R-BTA-71303 https://reactome.org/PathwayBrowser/#/R-BTA-71303 RPE dimers isomerise RU5P to XY5P IEA Bos taurus 58121 R-BTA-71306 https://reactome.org/PathwayBrowser/#/R-BTA-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Bos taurus 58121 R-CEL-177784 https://reactome.org/PathwayBrowser/#/R-CEL-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Caenorhabditis elegans 58121 R-CEL-199803 https://reactome.org/PathwayBrowser/#/R-CEL-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Caenorhabditis elegans 58121 R-CEL-71299 https://reactome.org/PathwayBrowser/#/R-CEL-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 58121 R-CEL-71303 https://reactome.org/PathwayBrowser/#/R-CEL-71303 RPE dimers isomerise RU5P to XY5P IEA Caenorhabditis elegans 58121 R-CEL-71306 https://reactome.org/PathwayBrowser/#/R-CEL-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Caenorhabditis elegans 58121 R-CFA-177784 https://reactome.org/PathwayBrowser/#/R-CFA-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Canis familiaris 58121 R-CFA-199803 https://reactome.org/PathwayBrowser/#/R-CFA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Canis familiaris 58121 R-CFA-71299 https://reactome.org/PathwayBrowser/#/R-CFA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Canis familiaris 58121 R-CFA-71303 https://reactome.org/PathwayBrowser/#/R-CFA-71303 RPE dimers isomerise RU5P to XY5P IEA Canis familiaris 58121 R-CFA-71306 https://reactome.org/PathwayBrowser/#/R-CFA-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Canis familiaris 58121 R-DDI-177784 https://reactome.org/PathwayBrowser/#/R-DDI-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Dictyostelium discoideum 58121 R-DDI-199803 https://reactome.org/PathwayBrowser/#/R-DDI-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Dictyostelium discoideum 58121 R-DDI-71299 https://reactome.org/PathwayBrowser/#/R-DDI-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 58121 R-DDI-71303 https://reactome.org/PathwayBrowser/#/R-DDI-71303 RPE dimers isomerise RU5P to XY5P IEA Dictyostelium discoideum 58121 R-DDI-71306 https://reactome.org/PathwayBrowser/#/R-DDI-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Dictyostelium discoideum 58121 R-DME-177784 https://reactome.org/PathwayBrowser/#/R-DME-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Drosophila melanogaster 58121 R-DME-199803 https://reactome.org/PathwayBrowser/#/R-DME-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Drosophila melanogaster 58121 R-DME-71299 https://reactome.org/PathwayBrowser/#/R-DME-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Drosophila melanogaster 58121 R-DME-71303 https://reactome.org/PathwayBrowser/#/R-DME-71303 RPE dimers isomerise RU5P to XY5P IEA Drosophila melanogaster 58121 R-DME-71306 https://reactome.org/PathwayBrowser/#/R-DME-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Drosophila melanogaster 58121 R-DRE-177784 https://reactome.org/PathwayBrowser/#/R-DRE-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Danio rerio 58121 R-DRE-199803 https://reactome.org/PathwayBrowser/#/R-DRE-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Danio rerio 58121 R-DRE-71299 https://reactome.org/PathwayBrowser/#/R-DRE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Danio rerio 58121 R-DRE-71303 https://reactome.org/PathwayBrowser/#/R-DRE-71303 RPE dimers isomerise RU5P to XY5P IEA Danio rerio 58121 R-DRE-71306 https://reactome.org/PathwayBrowser/#/R-DRE-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Danio rerio 58121 R-GGA-177784 https://reactome.org/PathwayBrowser/#/R-GGA-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Gallus gallus 58121 R-GGA-199803 https://reactome.org/PathwayBrowser/#/R-GGA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Gallus gallus 58121 R-GGA-71299 https://reactome.org/PathwayBrowser/#/R-GGA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Gallus gallus 58121 R-GGA-71303 https://reactome.org/PathwayBrowser/#/R-GGA-71303 RPE dimers isomerise RU5P to XY5P IEA Gallus gallus 58121 R-GGA-71306 https://reactome.org/PathwayBrowser/#/R-GGA-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Gallus gallus 58121 R-HSA-177784 https://reactome.org/PathwayBrowser/#/R-HSA-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate TAS Homo sapiens 58121 R-HSA-199803 https://reactome.org/PathwayBrowser/#/R-HSA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate TAS Homo sapiens 58121 R-HSA-5660013 https://reactome.org/PathwayBrowser/#/R-HSA-5660013 Defective RPIA does not isomerize RU5P to R5P TAS Homo sapiens 58121 R-HSA-71299 https://reactome.org/PathwayBrowser/#/R-HSA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ TAS Homo sapiens 58121 R-HSA-71303 https://reactome.org/PathwayBrowser/#/R-HSA-71303 RPE dimers isomerise RU5P to XY5P TAS Homo sapiens 58121 R-HSA-71306 https://reactome.org/PathwayBrowser/#/R-HSA-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate TAS Homo sapiens 58121 R-MMU-177784 https://reactome.org/PathwayBrowser/#/R-MMU-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Mus musculus 58121 R-MMU-199803 https://reactome.org/PathwayBrowser/#/R-MMU-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Mus musculus 58121 R-MMU-71299 https://reactome.org/PathwayBrowser/#/R-MMU-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Mus musculus 58121 R-MMU-71303 https://reactome.org/PathwayBrowser/#/R-MMU-71303 RPE dimers isomerise RU5P to XY5P IEA Mus musculus 58121 R-MMU-71306 https://reactome.org/PathwayBrowser/#/R-MMU-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Mus musculus 58121 R-PFA-199803 https://reactome.org/PathwayBrowser/#/R-PFA-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Plasmodium falciparum 58121 R-PFA-71303 https://reactome.org/PathwayBrowser/#/R-PFA-71303 RPE dimers isomerise RU5P to XY5P IEA Plasmodium falciparum 58121 R-RNO-177784 https://reactome.org/PathwayBrowser/#/R-RNO-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Rattus norvegicus 58121 R-RNO-199803 https://reactome.org/PathwayBrowser/#/R-RNO-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Rattus norvegicus 58121 R-RNO-71299 https://reactome.org/PathwayBrowser/#/R-RNO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Rattus norvegicus 58121 R-RNO-71303 https://reactome.org/PathwayBrowser/#/R-RNO-71303 RPE dimers isomerise RU5P to XY5P IEA Rattus norvegicus 58121 R-RNO-71306 https://reactome.org/PathwayBrowser/#/R-RNO-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Rattus norvegicus 58121 R-SCE-177784 https://reactome.org/PathwayBrowser/#/R-SCE-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Saccharomyces cerevisiae 58121 R-SCE-199803 https://reactome.org/PathwayBrowser/#/R-SCE-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Saccharomyces cerevisiae 58121 R-SCE-71299 https://reactome.org/PathwayBrowser/#/R-SCE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 58121 R-SCE-71303 https://reactome.org/PathwayBrowser/#/R-SCE-71303 RPE dimers isomerise RU5P to XY5P IEA Saccharomyces cerevisiae 58121 R-SCE-71306 https://reactome.org/PathwayBrowser/#/R-SCE-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Saccharomyces cerevisiae 58121 R-SPO-177784 https://reactome.org/PathwayBrowser/#/R-SPO-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Schizosaccharomyces pombe 58121 R-SPO-199803 https://reactome.org/PathwayBrowser/#/R-SPO-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Schizosaccharomyces pombe 58121 R-SPO-71299 https://reactome.org/PathwayBrowser/#/R-SPO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 58121 R-SPO-71303 https://reactome.org/PathwayBrowser/#/R-SPO-71303 RPE dimers isomerise RU5P to XY5P IEA Schizosaccharomyces pombe 58121 R-SPO-71306 https://reactome.org/PathwayBrowser/#/R-SPO-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Schizosaccharomyces pombe 58121 R-SSC-177784 https://reactome.org/PathwayBrowser/#/R-SSC-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Sus scrofa 58121 R-SSC-199803 https://reactome.org/PathwayBrowser/#/R-SSC-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Sus scrofa 58121 R-SSC-71299 https://reactome.org/PathwayBrowser/#/R-SSC-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Sus scrofa 58121 R-SSC-71303 https://reactome.org/PathwayBrowser/#/R-SSC-71303 RPE dimers isomerise RU5P to XY5P IEA Sus scrofa 58121 R-SSC-71306 https://reactome.org/PathwayBrowser/#/R-SSC-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Sus scrofa 58121 R-XTR-177784 https://reactome.org/PathwayBrowser/#/R-XTR-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Xenopus tropicalis 58121 R-XTR-199803 https://reactome.org/PathwayBrowser/#/R-XTR-199803 xylulose 5-phosphate <=> D-ribulose 5-phosphate IEA Xenopus tropicalis 58121 R-XTR-71303 https://reactome.org/PathwayBrowser/#/R-XTR-71303 RPE dimers isomerise RU5P to XY5P IEA Xenopus tropicalis 58121 R-XTR-71306 https://reactome.org/PathwayBrowser/#/R-XTR-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Xenopus tropicalis 58126 R-BTA-189406 https://reactome.org/PathwayBrowser/#/R-BTA-189406 4 PBGs bind to form HMB IEA Bos taurus 58126 R-BTA-189439 https://reactome.org/PathwayBrowser/#/R-BTA-189439 ALAD condenses 2 dALAs to form PBG IEA Bos taurus 58126 R-CFA-189406 https://reactome.org/PathwayBrowser/#/R-CFA-189406 4 PBGs bind to form HMB IEA Canis familiaris 58126 R-CFA-189439 https://reactome.org/PathwayBrowser/#/R-CFA-189439 ALAD condenses 2 dALAs to form PBG IEA Canis familiaris 58126 R-DDI-189439 https://reactome.org/PathwayBrowser/#/R-DDI-189439 ALAD condenses 2 dALAs to form PBG IEA Dictyostelium discoideum 58126 R-DME-189406 https://reactome.org/PathwayBrowser/#/R-DME-189406 4 PBGs bind to form HMB IEA Drosophila melanogaster 58126 R-DME-189439 https://reactome.org/PathwayBrowser/#/R-DME-189439 ALAD condenses 2 dALAs to form PBG IEA Drosophila melanogaster 58126 R-DRE-189439 https://reactome.org/PathwayBrowser/#/R-DRE-189439 ALAD condenses 2 dALAs to form PBG IEA Danio rerio 58126 R-GGA-189406 https://reactome.org/PathwayBrowser/#/R-GGA-189406 4 PBGs bind to form HMB IEA Gallus gallus 58126 R-GGA-189439 https://reactome.org/PathwayBrowser/#/R-GGA-189439 ALAD condenses 2 dALAs to form PBG IEA Gallus gallus 58126 R-GGA-421439 https://reactome.org/PathwayBrowser/#/R-GGA-421439 4 porphobilinogen + H2O => hydroxymethylbilane + 4 NH3 IEA Gallus gallus 58126 R-GGA-421472 https://reactome.org/PathwayBrowser/#/R-GGA-421472 2 delta-aminolevulinate => porphobilinogen + 2 H2O IEA Gallus gallus 58126 R-HSA-189406 https://reactome.org/PathwayBrowser/#/R-HSA-189406 4 PBGs bind to form HMB TAS Homo sapiens 58126 R-HSA-189439 https://reactome.org/PathwayBrowser/#/R-HSA-189439 ALAD condenses 2 dALAs to form PBG TAS Homo sapiens 58126 R-MMU-189406 https://reactome.org/PathwayBrowser/#/R-MMU-189406 4 PBGs bind to form HMB IEA Mus musculus 58126 R-MMU-189439 https://reactome.org/PathwayBrowser/#/R-MMU-189439 ALAD condenses 2 dALAs to form PBG IEA Mus musculus 58126 R-PFA-189406 https://reactome.org/PathwayBrowser/#/R-PFA-189406 4 PBGs bind to form HMB IEA Plasmodium falciparum 58126 R-PFA-189439 https://reactome.org/PathwayBrowser/#/R-PFA-189439 ALAD condenses 2 dALAs to form PBG IEA Plasmodium falciparum 58126 R-RNO-189406 https://reactome.org/PathwayBrowser/#/R-RNO-189406 4 PBGs bind to form HMB IEA Rattus norvegicus 58126 R-RNO-189439 https://reactome.org/PathwayBrowser/#/R-RNO-189439 ALAD condenses 2 dALAs to form PBG IEA Rattus norvegicus 58126 R-SCE-189406 https://reactome.org/PathwayBrowser/#/R-SCE-189406 4 PBGs bind to form HMB IEA Saccharomyces cerevisiae 58126 R-SCE-189439 https://reactome.org/PathwayBrowser/#/R-SCE-189439 ALAD condenses 2 dALAs to form PBG IEA Saccharomyces cerevisiae 58126 R-SPO-189406 https://reactome.org/PathwayBrowser/#/R-SPO-189406 4 PBGs bind to form HMB IEA Schizosaccharomyces pombe 58126 R-SPO-189439 https://reactome.org/PathwayBrowser/#/R-SPO-189439 ALAD condenses 2 dALAs to form PBG IEA Schizosaccharomyces pombe 58126 R-SSC-189406 https://reactome.org/PathwayBrowser/#/R-SSC-189406 4 PBGs bind to form HMB IEA Sus scrofa 58126 R-SSC-189439 https://reactome.org/PathwayBrowser/#/R-SSC-189439 ALAD condenses 2 dALAs to form PBG IEA Sus scrofa 58126 R-XTR-189406 https://reactome.org/PathwayBrowser/#/R-XTR-189406 4 PBGs bind to form HMB IEA Xenopus tropicalis 58126 R-XTR-189439 https://reactome.org/PathwayBrowser/#/R-XTR-189439 ALAD condenses 2 dALAs to form PBG IEA Xenopus tropicalis 58130 R-BTA-1855176 https://reactome.org/PathwayBrowser/#/R-BTA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Bos taurus 58130 R-BTA-1855179 https://reactome.org/PathwayBrowser/#/R-BTA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Bos taurus 58130 R-BTA-1855198 https://reactome.org/PathwayBrowser/#/R-BTA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 58130 R-BTA-1855207 https://reactome.org/PathwayBrowser/#/R-BTA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Bos taurus 58130 R-BTA-1855216 https://reactome.org/PathwayBrowser/#/R-BTA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Bos taurus 58130 R-BTA-1855225 https://reactome.org/PathwayBrowser/#/R-BTA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Bos taurus 58130 R-BTA-1855227 https://reactome.org/PathwayBrowser/#/R-BTA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Bos taurus 58130 R-BTA-2023971 https://reactome.org/PathwayBrowser/#/R-BTA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 58130 R-BTA-9687638 https://reactome.org/PathwayBrowser/#/R-BTA-9687638 MLKL binds IP4, IP5 and IP6 IEA Bos taurus 58130 R-CEL-1855198 https://reactome.org/PathwayBrowser/#/R-CEL-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 58130 R-CEL-1855207 https://reactome.org/PathwayBrowser/#/R-CEL-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 58130 R-CEL-1855216 https://reactome.org/PathwayBrowser/#/R-CEL-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Caenorhabditis elegans 58130 R-CEL-1855227 https://reactome.org/PathwayBrowser/#/R-CEL-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 58130 R-CEL-2023971 https://reactome.org/PathwayBrowser/#/R-CEL-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 58130 R-CFA-1855176 https://reactome.org/PathwayBrowser/#/R-CFA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Canis familiaris 58130 R-CFA-1855179 https://reactome.org/PathwayBrowser/#/R-CFA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Canis familiaris 58130 R-CFA-1855198 https://reactome.org/PathwayBrowser/#/R-CFA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 58130 R-CFA-1855207 https://reactome.org/PathwayBrowser/#/R-CFA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Canis familiaris 58130 R-CFA-1855216 https://reactome.org/PathwayBrowser/#/R-CFA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Canis familiaris 58130 R-CFA-1855225 https://reactome.org/PathwayBrowser/#/R-CFA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Canis familiaris 58130 R-CFA-1855227 https://reactome.org/PathwayBrowser/#/R-CFA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Canis familiaris 58130 R-CFA-2023971 https://reactome.org/PathwayBrowser/#/R-CFA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 58130 R-DDI-1855198 https://reactome.org/PathwayBrowser/#/R-DDI-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 58130 R-DDI-1855207 https://reactome.org/PathwayBrowser/#/R-DDI-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 58130 R-DDI-1855225 https://reactome.org/PathwayBrowser/#/R-DDI-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 58130 R-DDI-1855227 https://reactome.org/PathwayBrowser/#/R-DDI-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 58130 R-DDI-2023971 https://reactome.org/PathwayBrowser/#/R-DDI-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 58130 R-DME-1855198 https://reactome.org/PathwayBrowser/#/R-DME-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 58130 R-DME-1855207 https://reactome.org/PathwayBrowser/#/R-DME-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 58130 R-DME-1855216 https://reactome.org/PathwayBrowser/#/R-DME-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Drosophila melanogaster 58130 R-DME-1855227 https://reactome.org/PathwayBrowser/#/R-DME-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 58130 R-DME-2023971 https://reactome.org/PathwayBrowser/#/R-DME-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 58130 R-DRE-1855176 https://reactome.org/PathwayBrowser/#/R-DRE-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Danio rerio 58130 R-DRE-1855179 https://reactome.org/PathwayBrowser/#/R-DRE-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Danio rerio 58130 R-DRE-1855198 https://reactome.org/PathwayBrowser/#/R-DRE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 58130 R-DRE-1855207 https://reactome.org/PathwayBrowser/#/R-DRE-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Danio rerio 58130 R-DRE-1855225 https://reactome.org/PathwayBrowser/#/R-DRE-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Danio rerio 58130 R-DRE-1855227 https://reactome.org/PathwayBrowser/#/R-DRE-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Danio rerio 58130 R-DRE-2023971 https://reactome.org/PathwayBrowser/#/R-DRE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 58130 R-GGA-1855176 https://reactome.org/PathwayBrowser/#/R-GGA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Gallus gallus 58130 R-GGA-1855179 https://reactome.org/PathwayBrowser/#/R-GGA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Gallus gallus 58130 R-GGA-1855198 https://reactome.org/PathwayBrowser/#/R-GGA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 58130 R-GGA-1855207 https://reactome.org/PathwayBrowser/#/R-GGA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Gallus gallus 58130 R-GGA-1855216 https://reactome.org/PathwayBrowser/#/R-GGA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Gallus gallus 58130 R-GGA-1855225 https://reactome.org/PathwayBrowser/#/R-GGA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Gallus gallus 58130 R-GGA-1855227 https://reactome.org/PathwayBrowser/#/R-GGA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Gallus gallus 58130 R-GGA-2023971 https://reactome.org/PathwayBrowser/#/R-GGA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 58130 R-HSA-1855164 https://reactome.org/PathwayBrowser/#/R-HSA-1855164 IP6 transports from the cytosol to the ER lumen TAS Homo sapiens 58130 R-HSA-1855176 https://reactome.org/PathwayBrowser/#/R-HSA-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus TAS Homo sapiens 58130 R-HSA-1855179 https://reactome.org/PathwayBrowser/#/R-HSA-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol TAS Homo sapiens 58130 R-HSA-1855187 https://reactome.org/PathwayBrowser/#/R-HSA-1855187 IP6 transports from the nucleus to the ER lumen TAS Homo sapiens 58130 R-HSA-1855188 https://reactome.org/PathwayBrowser/#/R-HSA-1855188 IP6 transports from the cytosol to the nucleus TAS Homo sapiens 58130 R-HSA-1855198 https://reactome.org/PathwayBrowser/#/R-HSA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 58130 R-HSA-1855207 https://reactome.org/PathwayBrowser/#/R-HSA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus TAS Homo sapiens 58130 R-HSA-1855216 https://reactome.org/PathwayBrowser/#/R-HSA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol TAS Homo sapiens 58130 R-HSA-1855225 https://reactome.org/PathwayBrowser/#/R-HSA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen TAS Homo sapiens 58130 R-HSA-1855227 https://reactome.org/PathwayBrowser/#/R-HSA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol TAS Homo sapiens 58130 R-HSA-2023971 https://reactome.org/PathwayBrowser/#/R-HSA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 58130 R-HSA-5357927 https://reactome.org/PathwayBrowser/#/R-HSA-5357927 MLKL oligomerizes TAS Homo sapiens 58130 R-HSA-9687638 https://reactome.org/PathwayBrowser/#/R-HSA-9687638 MLKL binds IP4, IP5 and IP6 TAS Homo sapiens 58130 R-MMU-1855176 https://reactome.org/PathwayBrowser/#/R-MMU-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Mus musculus 58130 R-MMU-1855179 https://reactome.org/PathwayBrowser/#/R-MMU-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Mus musculus 58130 R-MMU-1855198 https://reactome.org/PathwayBrowser/#/R-MMU-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 58130 R-MMU-1855207 https://reactome.org/PathwayBrowser/#/R-MMU-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Mus musculus 58130 R-MMU-1855216 https://reactome.org/PathwayBrowser/#/R-MMU-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Mus musculus 58130 R-MMU-1855225 https://reactome.org/PathwayBrowser/#/R-MMU-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Mus musculus 58130 R-MMU-1855227 https://reactome.org/PathwayBrowser/#/R-MMU-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Mus musculus 58130 R-MMU-2023971 https://reactome.org/PathwayBrowser/#/R-MMU-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 58130 R-MMU-9687638 https://reactome.org/PathwayBrowser/#/R-MMU-9687638 MLKL binds IP4, IP5 and IP6 IEA Mus musculus 58130 R-PFA-1855207 https://reactome.org/PathwayBrowser/#/R-PFA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 58130 R-PFA-1855216 https://reactome.org/PathwayBrowser/#/R-PFA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Plasmodium falciparum 58130 R-PFA-1855227 https://reactome.org/PathwayBrowser/#/R-PFA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 58130 R-RNO-1855176 https://reactome.org/PathwayBrowser/#/R-RNO-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Rattus norvegicus 58130 R-RNO-1855179 https://reactome.org/PathwayBrowser/#/R-RNO-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Rattus norvegicus 58130 R-RNO-1855198 https://reactome.org/PathwayBrowser/#/R-RNO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 58130 R-RNO-1855207 https://reactome.org/PathwayBrowser/#/R-RNO-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Rattus norvegicus 58130 R-RNO-1855216 https://reactome.org/PathwayBrowser/#/R-RNO-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Rattus norvegicus 58130 R-RNO-1855225 https://reactome.org/PathwayBrowser/#/R-RNO-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Rattus norvegicus 58130 R-RNO-1855227 https://reactome.org/PathwayBrowser/#/R-RNO-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Rattus norvegicus 58130 R-RNO-2023971 https://reactome.org/PathwayBrowser/#/R-RNO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 58130 R-RNO-9687638 https://reactome.org/PathwayBrowser/#/R-RNO-9687638 MLKL binds IP4, IP5 and IP6 IEA Rattus norvegicus 58130 R-SCE-1855198 https://reactome.org/PathwayBrowser/#/R-SCE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 58130 R-SCE-1855207 https://reactome.org/PathwayBrowser/#/R-SCE-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 58130 R-SCE-1855216 https://reactome.org/PathwayBrowser/#/R-SCE-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Saccharomyces cerevisiae 58130 R-SCE-1855227 https://reactome.org/PathwayBrowser/#/R-SCE-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 58130 R-SCE-2023971 https://reactome.org/PathwayBrowser/#/R-SCE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 58130 R-SPO-1855198 https://reactome.org/PathwayBrowser/#/R-SPO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 58130 R-SPO-1855207 https://reactome.org/PathwayBrowser/#/R-SPO-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 58130 R-SPO-1855216 https://reactome.org/PathwayBrowser/#/R-SPO-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Schizosaccharomyces pombe 58130 R-SPO-1855227 https://reactome.org/PathwayBrowser/#/R-SPO-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 58130 R-SPO-2023971 https://reactome.org/PathwayBrowser/#/R-SPO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 58130 R-SSC-1855176 https://reactome.org/PathwayBrowser/#/R-SSC-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Sus scrofa 58130 R-SSC-1855179 https://reactome.org/PathwayBrowser/#/R-SSC-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Sus scrofa 58130 R-SSC-1855198 https://reactome.org/PathwayBrowser/#/R-SSC-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 58130 R-SSC-1855207 https://reactome.org/PathwayBrowser/#/R-SSC-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Sus scrofa 58130 R-SSC-1855216 https://reactome.org/PathwayBrowser/#/R-SSC-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Sus scrofa 58130 R-SSC-1855225 https://reactome.org/PathwayBrowser/#/R-SSC-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Sus scrofa 58130 R-SSC-1855227 https://reactome.org/PathwayBrowser/#/R-SSC-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Sus scrofa 58130 R-SSC-2023971 https://reactome.org/PathwayBrowser/#/R-SSC-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 58130 R-SSC-9687638 https://reactome.org/PathwayBrowser/#/R-SSC-9687638 MLKL binds IP4, IP5 and IP6 IEA Sus scrofa 58130 R-XTR-1855176 https://reactome.org/PathwayBrowser/#/R-XTR-1855176 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus IEA Xenopus tropicalis 58130 R-XTR-1855179 https://reactome.org/PathwayBrowser/#/R-XTR-1855179 I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol IEA Xenopus tropicalis 58130 R-XTR-1855198 https://reactome.org/PathwayBrowser/#/R-XTR-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 58130 R-XTR-1855207 https://reactome.org/PathwayBrowser/#/R-XTR-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 58130 R-XTR-1855216 https://reactome.org/PathwayBrowser/#/R-XTR-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Xenopus tropicalis 58130 R-XTR-1855225 https://reactome.org/PathwayBrowser/#/R-XTR-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Xenopus tropicalis 58130 R-XTR-1855227 https://reactome.org/PathwayBrowser/#/R-XTR-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 58130 R-XTR-2023971 https://reactome.org/PathwayBrowser/#/R-XTR-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 58145 R-BTA-350598 https://reactome.org/PathwayBrowser/#/R-BTA-350598 Arginine<=>Agmatine+CO2 IEA Bos taurus 58145 R-BTA-350604 https://reactome.org/PathwayBrowser/#/R-BTA-350604 Agmatine + H2O <=> putrescine + urea IEA Bos taurus 58145 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 58145 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 58145 R-CEL-350598 https://reactome.org/PathwayBrowser/#/R-CEL-350598 Arginine<=>Agmatine+CO2 IEA Caenorhabditis elegans 58145 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 58145 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 58145 R-CFA-350598 https://reactome.org/PathwayBrowser/#/R-CFA-350598 Arginine<=>Agmatine+CO2 IEA Canis familiaris 58145 R-CFA-350604 https://reactome.org/PathwayBrowser/#/R-CFA-350604 Agmatine + H2O <=> putrescine + urea IEA Canis familiaris 58145 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 58145 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 58145 R-DDI-350598 https://reactome.org/PathwayBrowser/#/R-DDI-350598 Arginine<=>Agmatine+CO2 IEA Dictyostelium discoideum 58145 R-DME-350598 https://reactome.org/PathwayBrowser/#/R-DME-350598 Arginine<=>Agmatine+CO2 IEA Drosophila melanogaster 58145 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 58145 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 58145 R-DRE-350598 https://reactome.org/PathwayBrowser/#/R-DRE-350598 Arginine<=>Agmatine+CO2 IEA Danio rerio 58145 R-DRE-350604 https://reactome.org/PathwayBrowser/#/R-DRE-350604 Agmatine + H2O <=> putrescine + urea IEA Danio rerio 58145 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 58145 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 58145 R-GGA-350598 https://reactome.org/PathwayBrowser/#/R-GGA-350598 Arginine<=>Agmatine+CO2 IEA Gallus gallus 58145 R-GGA-350604 https://reactome.org/PathwayBrowser/#/R-GGA-350604 Agmatine + H2O <=> putrescine + urea IEA Gallus gallus 58145 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 58145 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 58145 R-HSA-350598 https://reactome.org/PathwayBrowser/#/R-HSA-350598 Arginine<=>Agmatine+CO2 TAS Homo sapiens 58145 R-HSA-350604 https://reactome.org/PathwayBrowser/#/R-HSA-350604 Agmatine + H2O <=> putrescine + urea TAS Homo sapiens 58145 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 58145 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 58145 R-MMU-350598 https://reactome.org/PathwayBrowser/#/R-MMU-350598 Arginine<=>Agmatine+CO2 IEA Mus musculus 58145 R-MMU-350604 https://reactome.org/PathwayBrowser/#/R-MMU-350604 Agmatine + H2O <=> putrescine + urea IEA Mus musculus 58145 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 58145 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 58145 R-PFA-350598 https://reactome.org/PathwayBrowser/#/R-PFA-350598 Arginine<=>Agmatine+CO2 IEA Plasmodium falciparum 58145 R-RNO-350598 https://reactome.org/PathwayBrowser/#/R-RNO-350598 Arginine<=>Agmatine+CO2 IEA Rattus norvegicus 58145 R-RNO-350604 https://reactome.org/PathwayBrowser/#/R-RNO-350604 Agmatine + H2O <=> putrescine + urea IEA Rattus norvegicus 58145 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 58145 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 58145 R-SCE-350598 https://reactome.org/PathwayBrowser/#/R-SCE-350598 Arginine<=>Agmatine+CO2 IEA Saccharomyces cerevisiae 58145 R-SPO-350598 https://reactome.org/PathwayBrowser/#/R-SPO-350598 Arginine<=>Agmatine+CO2 IEA Schizosaccharomyces pombe 58145 R-SSC-350598 https://reactome.org/PathwayBrowser/#/R-SSC-350598 Arginine<=>Agmatine+CO2 IEA Sus scrofa 58145 R-SSC-350604 https://reactome.org/PathwayBrowser/#/R-SSC-350604 Agmatine + H2O <=> putrescine + urea IEA Sus scrofa 58145 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 58145 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 58145 R-XTR-350604 https://reactome.org/PathwayBrowser/#/R-XTR-350604 Agmatine + H2O <=> putrescine + urea IEA Xenopus tropicalis 58145 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 58145 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 58146 R-BTA-191380 https://reactome.org/PathwayBrowser/#/R-BTA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Bos taurus 58146 R-BTA-191422 https://reactome.org/PathwayBrowser/#/R-BTA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Bos taurus 58146 R-CEL-191380 https://reactome.org/PathwayBrowser/#/R-CEL-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Caenorhabditis elegans 58146 R-CEL-191422 https://reactome.org/PathwayBrowser/#/R-CEL-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Caenorhabditis elegans 58146 R-CFA-191380 https://reactome.org/PathwayBrowser/#/R-CFA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Canis familiaris 58146 R-CFA-191422 https://reactome.org/PathwayBrowser/#/R-CFA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Canis familiaris 58146 R-DDI-191380 https://reactome.org/PathwayBrowser/#/R-DDI-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Dictyostelium discoideum 58146 R-DME-191380 https://reactome.org/PathwayBrowser/#/R-DME-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Drosophila melanogaster 58146 R-DME-191422 https://reactome.org/PathwayBrowser/#/R-DME-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Drosophila melanogaster 58146 R-DRE-191380 https://reactome.org/PathwayBrowser/#/R-DRE-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Danio rerio 58146 R-DRE-191422 https://reactome.org/PathwayBrowser/#/R-DRE-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Danio rerio 58146 R-GGA-191380 https://reactome.org/PathwayBrowser/#/R-GGA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Gallus gallus 58146 R-GGA-191422 https://reactome.org/PathwayBrowser/#/R-GGA-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Gallus gallus 58146 R-HSA-191380 https://reactome.org/PathwayBrowser/#/R-HSA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate TAS Homo sapiens 58146 R-HSA-191422 https://reactome.org/PathwayBrowser/#/R-HSA-191422 Mevalonate-5-phosphate is further phosphorylated. TAS Homo sapiens 58146 R-MMU-191380 https://reactome.org/PathwayBrowser/#/R-MMU-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Mus musculus 58146 R-MMU-191422 https://reactome.org/PathwayBrowser/#/R-MMU-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Mus musculus 58146 R-RNO-191380 https://reactome.org/PathwayBrowser/#/R-RNO-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Rattus norvegicus 58146 R-RNO-191422 https://reactome.org/PathwayBrowser/#/R-RNO-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Rattus norvegicus 58146 R-SCE-191380 https://reactome.org/PathwayBrowser/#/R-SCE-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Saccharomyces cerevisiae 58146 R-SPO-191380 https://reactome.org/PathwayBrowser/#/R-SPO-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Schizosaccharomyces pombe 58146 R-SSC-191380 https://reactome.org/PathwayBrowser/#/R-SSC-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Sus scrofa 58146 R-SSC-191422 https://reactome.org/PathwayBrowser/#/R-SSC-191422 Mevalonate-5-phosphate is further phosphorylated. IEA Sus scrofa 58165 R-BTA-111925 https://reactome.org/PathwayBrowser/#/R-BTA-111925 cAMP induces dissociation of inactive PKA tetramers IEA Bos taurus 58165 R-BTA-111930 https://reactome.org/PathwayBrowser/#/R-BTA-111930 Adenylate cyclase produces cAMP IEA Bos taurus 58165 R-BTA-111955 https://reactome.org/PathwayBrowser/#/R-BTA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Bos taurus 58165 R-BTA-111962 https://reactome.org/PathwayBrowser/#/R-BTA-111962 PDE4A,C,D hydrolyse cAMP IEA Bos taurus 58165 R-BTA-1296043 https://reactome.org/PathwayBrowser/#/R-BTA-1296043 Activation of HCN channels IEA Bos taurus 58165 R-BTA-1297444 https://reactome.org/PathwayBrowser/#/R-BTA-1297444 Binding of cAMP to HCN channels IEA Bos taurus 58165 R-BTA-162425 https://reactome.org/PathwayBrowser/#/R-BTA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Bos taurus 58165 R-BTA-170676 https://reactome.org/PathwayBrowser/#/R-BTA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Bos taurus 58165 R-BTA-265682 https://reactome.org/PathwayBrowser/#/R-BTA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Bos taurus 58165 R-BTA-381608 https://reactome.org/PathwayBrowser/#/R-BTA-381608 cAMP activates EPAC2 IEA Bos taurus 58165 R-BTA-381668 https://reactome.org/PathwayBrowser/#/R-BTA-381668 cAMP activates EPAC1 IEA Bos taurus 58165 R-BTA-381727 https://reactome.org/PathwayBrowser/#/R-BTA-381727 RAP1A exchanges GDP for GTP IEA Bos taurus 58165 R-BTA-392834 https://reactome.org/PathwayBrowser/#/R-BTA-392834 Activation of EPACs by cAMP IEA Bos taurus 58165 R-BTA-418553 https://reactome.org/PathwayBrowser/#/R-BTA-418553 cAMP degradation by Phosphodiesterases IEA Bos taurus 58165 R-BTA-5610727 https://reactome.org/PathwayBrowser/#/R-BTA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Bos taurus 58165 R-BTA-5610749 https://reactome.org/PathwayBrowser/#/R-BTA-5610749 cAMP dissociates PKA, promoting GLI processing IEA Bos taurus 58165 R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 58165 R-BTA-8951727 https://reactome.org/PathwayBrowser/#/R-BTA-8951727 cAMP binds PKA tetramer IEA Bos taurus 58165 R-BTA-9629675 https://reactome.org/PathwayBrowser/#/R-BTA-9629675 PDE3A hydrolyses cAMP to AMP IEA Bos taurus 58165 R-BTA-9644869 https://reactome.org/PathwayBrowser/#/R-BTA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Bos taurus 58165 R-BTA-9705507 https://reactome.org/PathwayBrowser/#/R-BTA-9705507 PDE3B hydrolyses cAMP to AMP IEA Bos taurus 58165 R-BTA-9708261 https://reactome.org/PathwayBrowser/#/R-BTA-9708261 PDE4A hydrolyses cAMP to AMP IEA Bos taurus 58165 R-BTA-9726875 https://reactome.org/PathwayBrowser/#/R-BTA-9726875 HCNs:cAMP bind SNIs IEA Bos taurus 58165 R-CEL-111925 https://reactome.org/PathwayBrowser/#/R-CEL-111925 cAMP induces dissociation of inactive PKA tetramers IEA Caenorhabditis elegans 58165 R-CEL-111930 https://reactome.org/PathwayBrowser/#/R-CEL-111930 Adenylate cyclase produces cAMP IEA Caenorhabditis elegans 58165 R-CEL-111955 https://reactome.org/PathwayBrowser/#/R-CEL-111955 cAMP hydrolysis by Cam-PDE 1 IEA Caenorhabditis elegans 58165 R-CEL-111962 https://reactome.org/PathwayBrowser/#/R-CEL-111962 PDE4A,C,D hydrolyse cAMP IEA Caenorhabditis elegans 58165 R-CEL-162425 https://reactome.org/PathwayBrowser/#/R-CEL-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Caenorhabditis elegans 58165 R-CEL-170676 https://reactome.org/PathwayBrowser/#/R-CEL-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Caenorhabditis elegans 58165 R-CEL-381608 https://reactome.org/PathwayBrowser/#/R-CEL-381608 cAMP activates EPAC2 IEA Caenorhabditis elegans 58165 R-CEL-381668 https://reactome.org/PathwayBrowser/#/R-CEL-381668 cAMP activates EPAC1 IEA Caenorhabditis elegans 58165 R-CEL-381727 https://reactome.org/PathwayBrowser/#/R-CEL-381727 RAP1A exchanges GDP for GTP IEA Caenorhabditis elegans 58165 R-CEL-392834 https://reactome.org/PathwayBrowser/#/R-CEL-392834 Activation of EPACs by cAMP IEA Caenorhabditis elegans 58165 R-CEL-418553 https://reactome.org/PathwayBrowser/#/R-CEL-418553 cAMP degradation by Phosphodiesterases IEA Caenorhabditis elegans 58165 R-CEL-5610727 https://reactome.org/PathwayBrowser/#/R-CEL-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Caenorhabditis elegans 58165 R-CEL-5610749 https://reactome.org/PathwayBrowser/#/R-CEL-5610749 cAMP dissociates PKA, promoting GLI processing IEA Caenorhabditis elegans 58165 R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 58165 R-CEL-8951727 https://reactome.org/PathwayBrowser/#/R-CEL-8951727 cAMP binds PKA tetramer IEA Caenorhabditis elegans 58165 R-CEL-9629675 https://reactome.org/PathwayBrowser/#/R-CEL-9629675 PDE3A hydrolyses cAMP to AMP IEA Caenorhabditis elegans 58165 R-CEL-9644869 https://reactome.org/PathwayBrowser/#/R-CEL-9644869 p-S54-PDE4B hydrolyses cAMP IEA Caenorhabditis elegans 58165 R-CEL-9705507 https://reactome.org/PathwayBrowser/#/R-CEL-9705507 PDE3B hydrolyses cAMP to AMP IEA Caenorhabditis elegans 58165 R-CEL-9708261 https://reactome.org/PathwayBrowser/#/R-CEL-9708261 PDE4A hydrolyses cAMP to AMP IEA Caenorhabditis elegans 58165 R-CFA-111925 https://reactome.org/PathwayBrowser/#/R-CFA-111925 cAMP induces dissociation of inactive PKA tetramers IEA Canis familiaris 58165 R-CFA-111930 https://reactome.org/PathwayBrowser/#/R-CFA-111930 Adenylate cyclase produces cAMP IEA Canis familiaris 58165 R-CFA-111955 https://reactome.org/PathwayBrowser/#/R-CFA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Canis familiaris 58165 R-CFA-111962 https://reactome.org/PathwayBrowser/#/R-CFA-111962 PDE4A,C,D hydrolyse cAMP IEA Canis familiaris 58165 R-CFA-1296043 https://reactome.org/PathwayBrowser/#/R-CFA-1296043 Activation of HCN channels IEA Canis familiaris 58165 R-CFA-1297444 https://reactome.org/PathwayBrowser/#/R-CFA-1297444 Binding of cAMP to HCN channels IEA Canis familiaris 58165 R-CFA-162425 https://reactome.org/PathwayBrowser/#/R-CFA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Canis familiaris 58165 R-CFA-170676 https://reactome.org/PathwayBrowser/#/R-CFA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Canis familiaris 58165 R-CFA-265682 https://reactome.org/PathwayBrowser/#/R-CFA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Canis familiaris 58165 R-CFA-381608 https://reactome.org/PathwayBrowser/#/R-CFA-381608 cAMP activates EPAC2 IEA Canis familiaris 58165 R-CFA-381668 https://reactome.org/PathwayBrowser/#/R-CFA-381668 cAMP activates EPAC1 IEA Canis familiaris 58165 R-CFA-381727 https://reactome.org/PathwayBrowser/#/R-CFA-381727 RAP1A exchanges GDP for GTP IEA Canis familiaris 58165 R-CFA-392834 https://reactome.org/PathwayBrowser/#/R-CFA-392834 Activation of EPACs by cAMP IEA Canis familiaris 58165 R-CFA-418553 https://reactome.org/PathwayBrowser/#/R-CFA-418553 cAMP degradation by Phosphodiesterases IEA Canis familiaris 58165 R-CFA-421879 https://reactome.org/PathwayBrowser/#/R-CFA-421879 Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate TAS Canis familiaris 58165 R-CFA-5610727 https://reactome.org/PathwayBrowser/#/R-CFA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Canis familiaris 58165 R-CFA-5610749 https://reactome.org/PathwayBrowser/#/R-CFA-5610749 cAMP dissociates PKA, promoting GLI processing IEA Canis familiaris 58165 R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 58165 R-CFA-8951727 https://reactome.org/PathwayBrowser/#/R-CFA-8951727 cAMP binds PKA tetramer IEA Canis familiaris 58165 R-CFA-9629675 https://reactome.org/PathwayBrowser/#/R-CFA-9629675 PDE3A hydrolyses cAMP to AMP IEA Canis familiaris 58165 R-CFA-9644869 https://reactome.org/PathwayBrowser/#/R-CFA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Canis familiaris 58165 R-CFA-9705507 https://reactome.org/PathwayBrowser/#/R-CFA-9705507 PDE3B hydrolyses cAMP to AMP IEA Canis familiaris 58165 R-CFA-9708261 https://reactome.org/PathwayBrowser/#/R-CFA-9708261 PDE4A hydrolyses cAMP to AMP IEA Canis familiaris 58165 R-CFA-9726875 https://reactome.org/PathwayBrowser/#/R-CFA-9726875 HCNs:cAMP bind SNIs IEA Canis familiaris 58165 R-DDI-111930 https://reactome.org/PathwayBrowser/#/R-DDI-111930 Adenylate cyclase produces cAMP IEA Dictyostelium discoideum 58165 R-DDI-111955 https://reactome.org/PathwayBrowser/#/R-DDI-111955 cAMP hydrolysis by Cam-PDE 1 IEA Dictyostelium discoideum 58165 R-DDI-111962 https://reactome.org/PathwayBrowser/#/R-DDI-111962 PDE4A,C,D hydrolyse cAMP IEA Dictyostelium discoideum 58165 R-DDI-162425 https://reactome.org/PathwayBrowser/#/R-DDI-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Dictyostelium discoideum 58165 R-DDI-170676 https://reactome.org/PathwayBrowser/#/R-DDI-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Dictyostelium discoideum 58165 R-DDI-381608 https://reactome.org/PathwayBrowser/#/R-DDI-381608 cAMP activates EPAC2 IEA Dictyostelium discoideum 58165 R-DDI-381668 https://reactome.org/PathwayBrowser/#/R-DDI-381668 cAMP activates EPAC1 IEA Dictyostelium discoideum 58165 R-DDI-381727 https://reactome.org/PathwayBrowser/#/R-DDI-381727 RAP1A exchanges GDP for GTP IEA Dictyostelium discoideum 58165 R-DDI-392834 https://reactome.org/PathwayBrowser/#/R-DDI-392834 Activation of EPACs by cAMP IEA Dictyostelium discoideum 58165 R-DDI-418553 https://reactome.org/PathwayBrowser/#/R-DDI-418553 cAMP degradation by Phosphodiesterases IEA Dictyostelium discoideum 58165 R-DDI-5610727 https://reactome.org/PathwayBrowser/#/R-DDI-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Dictyostelium discoideum 58165 R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 58165 R-DDI-9629675 https://reactome.org/PathwayBrowser/#/R-DDI-9629675 PDE3A hydrolyses cAMP to AMP IEA Dictyostelium discoideum 58165 R-DDI-9644869 https://reactome.org/PathwayBrowser/#/R-DDI-9644869 p-S54-PDE4B hydrolyses cAMP IEA Dictyostelium discoideum 58165 R-DDI-9705507 https://reactome.org/PathwayBrowser/#/R-DDI-9705507 PDE3B hydrolyses cAMP to AMP IEA Dictyostelium discoideum 58165 R-DDI-9708261 https://reactome.org/PathwayBrowser/#/R-DDI-9708261 PDE4A hydrolyses cAMP to AMP IEA Dictyostelium discoideum 58165 R-DME-111925 https://reactome.org/PathwayBrowser/#/R-DME-111925 cAMP induces dissociation of inactive PKA tetramers IEA Drosophila melanogaster 58165 R-DME-111930 https://reactome.org/PathwayBrowser/#/R-DME-111930 Adenylate cyclase produces cAMP IEA Drosophila melanogaster 58165 R-DME-111955 https://reactome.org/PathwayBrowser/#/R-DME-111955 cAMP hydrolysis by Cam-PDE 1 IEA Drosophila melanogaster 58165 R-DME-111962 https://reactome.org/PathwayBrowser/#/R-DME-111962 PDE4A,C,D hydrolyse cAMP IEA Drosophila melanogaster 58165 R-DME-1296043 https://reactome.org/PathwayBrowser/#/R-DME-1296043 Activation of HCN channels IEA Drosophila melanogaster 58165 R-DME-1297444 https://reactome.org/PathwayBrowser/#/R-DME-1297444 Binding of cAMP to HCN channels IEA Drosophila melanogaster 58165 R-DME-170676 https://reactome.org/PathwayBrowser/#/R-DME-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Drosophila melanogaster 58165 R-DME-265682 https://reactome.org/PathwayBrowser/#/R-DME-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Drosophila melanogaster 58165 R-DME-381608 https://reactome.org/PathwayBrowser/#/R-DME-381608 cAMP activates EPAC2 IEA Drosophila melanogaster 58165 R-DME-381668 https://reactome.org/PathwayBrowser/#/R-DME-381668 cAMP activates EPAC1 IEA Drosophila melanogaster 58165 R-DME-381727 https://reactome.org/PathwayBrowser/#/R-DME-381727 RAP1A exchanges GDP for GTP IEA Drosophila melanogaster 58165 R-DME-392834 https://reactome.org/PathwayBrowser/#/R-DME-392834 Activation of EPACs by cAMP IEA Drosophila melanogaster 58165 R-DME-418553 https://reactome.org/PathwayBrowser/#/R-DME-418553 cAMP degradation by Phosphodiesterases IEA Drosophila melanogaster 58165 R-DME-5610727 https://reactome.org/PathwayBrowser/#/R-DME-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Drosophila melanogaster 58165 R-DME-5610749 https://reactome.org/PathwayBrowser/#/R-DME-5610749 cAMP dissociates PKA, promoting GLI processing IEA Drosophila melanogaster 58165 R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 58165 R-DME-8951727 https://reactome.org/PathwayBrowser/#/R-DME-8951727 cAMP binds PKA tetramer IEA Drosophila melanogaster 58165 R-DME-9644869 https://reactome.org/PathwayBrowser/#/R-DME-9644869 p-S54-PDE4B hydrolyses cAMP IEA Drosophila melanogaster 58165 R-DME-9708261 https://reactome.org/PathwayBrowser/#/R-DME-9708261 PDE4A hydrolyses cAMP to AMP IEA Drosophila melanogaster 58165 R-DME-9726875 https://reactome.org/PathwayBrowser/#/R-DME-9726875 HCNs:cAMP bind SNIs IEA Drosophila melanogaster 58165 R-DRE-111925 https://reactome.org/PathwayBrowser/#/R-DRE-111925 cAMP induces dissociation of inactive PKA tetramers IEA Danio rerio 58165 R-DRE-111930 https://reactome.org/PathwayBrowser/#/R-DRE-111930 Adenylate cyclase produces cAMP IEA Danio rerio 58165 R-DRE-170676 https://reactome.org/PathwayBrowser/#/R-DRE-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Danio rerio 58165 R-DRE-418553 https://reactome.org/PathwayBrowser/#/R-DRE-418553 cAMP degradation by Phosphodiesterases IEA Danio rerio 58165 R-DRE-5610727 https://reactome.org/PathwayBrowser/#/R-DRE-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Danio rerio 58165 R-DRE-5610749 https://reactome.org/PathwayBrowser/#/R-DRE-5610749 cAMP dissociates PKA, promoting GLI processing IEA Danio rerio 58165 R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 58165 R-DRE-8951727 https://reactome.org/PathwayBrowser/#/R-DRE-8951727 cAMP binds PKA tetramer IEA Danio rerio 58165 R-GGA-111925 https://reactome.org/PathwayBrowser/#/R-GGA-111925 cAMP induces dissociation of inactive PKA tetramers IEA Gallus gallus 58165 R-GGA-111930 https://reactome.org/PathwayBrowser/#/R-GGA-111930 Adenylate cyclase produces cAMP IEA Gallus gallus 58165 R-GGA-111955 https://reactome.org/PathwayBrowser/#/R-GGA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Gallus gallus 58165 R-GGA-111962 https://reactome.org/PathwayBrowser/#/R-GGA-111962 PDE4A,C,D hydrolyse cAMP IEA Gallus gallus 58165 R-GGA-1296043 https://reactome.org/PathwayBrowser/#/R-GGA-1296043 Activation of HCN channels IEA Gallus gallus 58165 R-GGA-1297444 https://reactome.org/PathwayBrowser/#/R-GGA-1297444 Binding of cAMP to HCN channels IEA Gallus gallus 58165 R-GGA-162425 https://reactome.org/PathwayBrowser/#/R-GGA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Gallus gallus 58165 R-GGA-170676 https://reactome.org/PathwayBrowser/#/R-GGA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Gallus gallus 58165 R-GGA-265682 https://reactome.org/PathwayBrowser/#/R-GGA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Gallus gallus 58165 R-GGA-381608 https://reactome.org/PathwayBrowser/#/R-GGA-381608 cAMP activates EPAC2 IEA Gallus gallus 58165 R-GGA-381668 https://reactome.org/PathwayBrowser/#/R-GGA-381668 cAMP activates EPAC1 IEA Gallus gallus 58165 R-GGA-381727 https://reactome.org/PathwayBrowser/#/R-GGA-381727 RAP1A exchanges GDP for GTP IEA Gallus gallus 58165 R-GGA-392834 https://reactome.org/PathwayBrowser/#/R-GGA-392834 Activation of EPACs by cAMP IEA Gallus gallus 58165 R-GGA-418553 https://reactome.org/PathwayBrowser/#/R-GGA-418553 cAMP degradation by Phosphodiesterases IEA Gallus gallus 58165 R-GGA-5610727 https://reactome.org/PathwayBrowser/#/R-GGA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Gallus gallus 58165 R-GGA-5610749 https://reactome.org/PathwayBrowser/#/R-GGA-5610749 cAMP dissociates PKA, promoting GLI processing IEA Gallus gallus 58165 R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 58165 R-GGA-8951727 https://reactome.org/PathwayBrowser/#/R-GGA-8951727 cAMP binds PKA tetramer IEA Gallus gallus 58165 R-GGA-9629675 https://reactome.org/PathwayBrowser/#/R-GGA-9629675 PDE3A hydrolyses cAMP to AMP IEA Gallus gallus 58165 R-GGA-9644869 https://reactome.org/PathwayBrowser/#/R-GGA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Gallus gallus 58165 R-GGA-9705507 https://reactome.org/PathwayBrowser/#/R-GGA-9705507 PDE3B hydrolyses cAMP to AMP IEA Gallus gallus 58165 R-GGA-9726875 https://reactome.org/PathwayBrowser/#/R-GGA-9726875 HCNs:cAMP bind SNIs IEA Gallus gallus 58165 R-HSA-111925 https://reactome.org/PathwayBrowser/#/R-HSA-111925 cAMP induces dissociation of inactive PKA tetramers TAS Homo sapiens 58165 R-HSA-111930 https://reactome.org/PathwayBrowser/#/R-HSA-111930 Adenylate cyclase produces cAMP TAS Homo sapiens 58165 R-HSA-111955 https://reactome.org/PathwayBrowser/#/R-HSA-111955 cAMP hydrolysis by Cam-PDE 1 TAS Homo sapiens 58165 R-HSA-111962 https://reactome.org/PathwayBrowser/#/R-HSA-111962 PDE4A,C,D hydrolyse cAMP TAS Homo sapiens 58165 R-HSA-1296043 https://reactome.org/PathwayBrowser/#/R-HSA-1296043 Activation of HCN channels TAS Homo sapiens 58165 R-HSA-1297444 https://reactome.org/PathwayBrowser/#/R-HSA-1297444 Binding of cAMP to HCN channels TAS Homo sapiens 58165 R-HSA-162425 https://reactome.org/PathwayBrowser/#/R-HSA-162425 p-S295-PDE3B hydrolyses cAMP to AMP TAS Homo sapiens 58165 R-HSA-164377 https://reactome.org/PathwayBrowser/#/R-HSA-164377 Activated Adenylate cyclase catalyses cAMP synthesis TAS Homo sapiens 58165 R-HSA-170676 https://reactome.org/PathwayBrowser/#/R-HSA-170676 Adenylate cyclase converts ATP into cyclic AMP TAS Homo sapiens 58165 R-HSA-265682 https://reactome.org/PathwayBrowser/#/R-HSA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel TAS Homo sapiens 58165 R-HSA-381607 https://reactome.org/PathwayBrowser/#/R-HSA-381607 Activated Adenylyl cyclase synthesizes cyclic AMP TAS Homo sapiens 58165 R-HSA-381608 https://reactome.org/PathwayBrowser/#/R-HSA-381608 cAMP activates EPAC2 TAS Homo sapiens 58165 R-HSA-381668 https://reactome.org/PathwayBrowser/#/R-HSA-381668 cAMP activates EPAC1 TAS Homo sapiens 58165 R-HSA-381707 https://reactome.org/PathwayBrowser/#/R-HSA-381707 PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP IEA Homo sapiens 58165 R-HSA-381727 https://reactome.org/PathwayBrowser/#/R-HSA-381727 RAP1A exchanges GDP for GTP TAS Homo sapiens 58165 R-HSA-392129 https://reactome.org/PathwayBrowser/#/R-HSA-392129 Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate IEA Homo sapiens 58165 R-HSA-392834 https://reactome.org/PathwayBrowser/#/R-HSA-392834 Activation of EPACs by cAMP TAS Homo sapiens 58165 R-HSA-418553 https://reactome.org/PathwayBrowser/#/R-HSA-418553 cAMP degradation by Phosphodiesterases TAS Homo sapiens 58165 R-HSA-442715 https://reactome.org/PathwayBrowser/#/R-HSA-442715 Calmodulin-activated adenylate cyclases ADCY1 and ADCY8 generate cAMP IEA Homo sapiens 58165 R-HSA-5211224 https://reactome.org/PathwayBrowser/#/R-HSA-5211224 Anthrax cya catalyzes the conversion of ATP to cAMP TAS Homo sapiens 58165 R-HSA-5610727 https://reactome.org/PathwayBrowser/#/R-HSA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner TAS Homo sapiens 58165 R-HSA-5610749 https://reactome.org/PathwayBrowser/#/R-HSA-5610749 cAMP dissociates PKA, promoting GLI processing TAS Homo sapiens 58165 R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 58165 R-HSA-8951727 https://reactome.org/PathwayBrowser/#/R-HSA-8951727 cAMP binds PKA tetramer TAS Homo sapiens 58165 R-HSA-9629675 https://reactome.org/PathwayBrowser/#/R-HSA-9629675 PDE3A hydrolyses cAMP to AMP TAS Homo sapiens 58165 R-HSA-9644869 https://reactome.org/PathwayBrowser/#/R-HSA-9644869 p-S54-PDE4B hydrolyses cAMP TAS Homo sapiens 58165 R-HSA-9705507 https://reactome.org/PathwayBrowser/#/R-HSA-9705507 PDE3B hydrolyses cAMP to AMP TAS Homo sapiens 58165 R-HSA-9708261 https://reactome.org/PathwayBrowser/#/R-HSA-9708261 PDE4A hydrolyses cAMP to AMP TAS Homo sapiens 58165 R-HSA-9712183 https://reactome.org/PathwayBrowser/#/R-HSA-9712183 ADCY3:GNAL:GTP converts ATP to cAMP IEA Homo sapiens 58165 R-HSA-9712190 https://reactome.org/PathwayBrowser/#/R-HSA-9712190 cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol IEA Homo sapiens 58165 R-HSA-9712199 https://reactome.org/PathwayBrowser/#/R-HSA-9712199 cAMP binds the olfactory CNG channel IEA Homo sapiens 58165 R-HSA-9726875 https://reactome.org/PathwayBrowser/#/R-HSA-9726875 HCNs:cAMP bind SNIs TAS Homo sapiens 58165 R-MMU-111925 https://reactome.org/PathwayBrowser/#/R-MMU-111925 cAMP induces dissociation of inactive PKA tetramers IEA Mus musculus 58165 R-MMU-111930 https://reactome.org/PathwayBrowser/#/R-MMU-111930 Adenylate cyclase produces cAMP IEA Mus musculus 58165 R-MMU-111955 https://reactome.org/PathwayBrowser/#/R-MMU-111955 cAMP hydrolysis by Cam-PDE 1 IEA Mus musculus 58165 R-MMU-111962 https://reactome.org/PathwayBrowser/#/R-MMU-111962 PDE4A,C,D hydrolyse cAMP IEA Mus musculus 58165 R-MMU-1296043 https://reactome.org/PathwayBrowser/#/R-MMU-1296043 Activation of HCN channels IEA Mus musculus 58165 R-MMU-1297444 https://reactome.org/PathwayBrowser/#/R-MMU-1297444 Binding of cAMP to HCN channels IEA Mus musculus 58165 R-MMU-162425 https://reactome.org/PathwayBrowser/#/R-MMU-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Mus musculus 58165 R-MMU-170676 https://reactome.org/PathwayBrowser/#/R-MMU-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Mus musculus 58165 R-MMU-265682 https://reactome.org/PathwayBrowser/#/R-MMU-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Mus musculus 58165 R-MMU-381608 https://reactome.org/PathwayBrowser/#/R-MMU-381608 cAMP activates EPAC2 IEA Mus musculus 58165 R-MMU-381668 https://reactome.org/PathwayBrowser/#/R-MMU-381668 cAMP activates EPAC1 IEA Mus musculus 58165 R-MMU-381727 https://reactome.org/PathwayBrowser/#/R-MMU-381727 RAP1A exchanges GDP for GTP IEA Mus musculus 58165 R-MMU-392834 https://reactome.org/PathwayBrowser/#/R-MMU-392834 Activation of EPACs by cAMP IEA Mus musculus 58165 R-MMU-418553 https://reactome.org/PathwayBrowser/#/R-MMU-418553 cAMP degradation by Phosphodiesterases IEA Mus musculus 58165 R-MMU-5610727 https://reactome.org/PathwayBrowser/#/R-MMU-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Mus musculus 58165 R-MMU-5610749 https://reactome.org/PathwayBrowser/#/R-MMU-5610749 cAMP dissociates PKA, promoting GLI processing IEA Mus musculus 58165 R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 58165 R-MMU-8951727 https://reactome.org/PathwayBrowser/#/R-MMU-8951727 cAMP binds PKA tetramer IEA Mus musculus 58165 R-MMU-9629675 https://reactome.org/PathwayBrowser/#/R-MMU-9629675 PDE3A hydrolyses cAMP to AMP IEA Mus musculus 58165 R-MMU-9644869 https://reactome.org/PathwayBrowser/#/R-MMU-9644869 p-S54-PDE4B hydrolyses cAMP IEA Mus musculus 58165 R-MMU-9705507 https://reactome.org/PathwayBrowser/#/R-MMU-9705507 PDE3B hydrolyses cAMP to AMP IEA Mus musculus 58165 R-MMU-9708261 https://reactome.org/PathwayBrowser/#/R-MMU-9708261 PDE4A hydrolyses cAMP to AMP IEA Mus musculus 58165 R-MMU-9713672 https://reactome.org/PathwayBrowser/#/R-MMU-9713672 cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol TAS Mus musculus 58165 R-MMU-9713712 https://reactome.org/PathwayBrowser/#/R-MMU-9713712 Adcy3:Gnal:GTP converts ATP to cAMP TAS Mus musculus 58165 R-MMU-9726875 https://reactome.org/PathwayBrowser/#/R-MMU-9726875 HCNs:cAMP bind SNIs IEA Mus musculus 58165 R-PFA-111955 https://reactome.org/PathwayBrowser/#/R-PFA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Plasmodium falciparum 58165 R-PFA-111962 https://reactome.org/PathwayBrowser/#/R-PFA-111962 PDE4A,C,D hydrolyse cAMP IEA Plasmodium falciparum 58165 R-PFA-162425 https://reactome.org/PathwayBrowser/#/R-PFA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Plasmodium falciparum 58165 R-PFA-418553 https://reactome.org/PathwayBrowser/#/R-PFA-418553 cAMP degradation by Phosphodiesterases IEA Plasmodium falciparum 58165 R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 58165 R-PFA-9629675 https://reactome.org/PathwayBrowser/#/R-PFA-9629675 PDE3A hydrolyses cAMP to AMP IEA Plasmodium falciparum 58165 R-PFA-9644869 https://reactome.org/PathwayBrowser/#/R-PFA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Plasmodium falciparum 58165 R-PFA-9705507 https://reactome.org/PathwayBrowser/#/R-PFA-9705507 PDE3B hydrolyses cAMP to AMP IEA Plasmodium falciparum 58165 R-PFA-9708261 https://reactome.org/PathwayBrowser/#/R-PFA-9708261 PDE4A hydrolyses cAMP to AMP IEA Plasmodium falciparum 58165 R-RNO-111925 https://reactome.org/PathwayBrowser/#/R-RNO-111925 cAMP induces dissociation of inactive PKA tetramers IEA Rattus norvegicus 58165 R-RNO-111930 https://reactome.org/PathwayBrowser/#/R-RNO-111930 Adenylate cyclase produces cAMP IEA Rattus norvegicus 58165 R-RNO-111955 https://reactome.org/PathwayBrowser/#/R-RNO-111955 cAMP hydrolysis by Cam-PDE 1 IEA Rattus norvegicus 58165 R-RNO-111962 https://reactome.org/PathwayBrowser/#/R-RNO-111962 PDE4A,C,D hydrolyse cAMP IEA Rattus norvegicus 58165 R-RNO-1296043 https://reactome.org/PathwayBrowser/#/R-RNO-1296043 Activation of HCN channels IEA Rattus norvegicus 58165 R-RNO-1297444 https://reactome.org/PathwayBrowser/#/R-RNO-1297444 Binding of cAMP to HCN channels IEA Rattus norvegicus 58165 R-RNO-162425 https://reactome.org/PathwayBrowser/#/R-RNO-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Rattus norvegicus 58165 R-RNO-170676 https://reactome.org/PathwayBrowser/#/R-RNO-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Rattus norvegicus 58165 R-RNO-265682 https://reactome.org/PathwayBrowser/#/R-RNO-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Rattus norvegicus 58165 R-RNO-381608 https://reactome.org/PathwayBrowser/#/R-RNO-381608 cAMP activates EPAC2 IEA Rattus norvegicus 58165 R-RNO-381668 https://reactome.org/PathwayBrowser/#/R-RNO-381668 cAMP activates EPAC1 IEA Rattus norvegicus 58165 R-RNO-381727 https://reactome.org/PathwayBrowser/#/R-RNO-381727 RAP1A exchanges GDP for GTP IEA Rattus norvegicus 58165 R-RNO-392834 https://reactome.org/PathwayBrowser/#/R-RNO-392834 Activation of EPACs by cAMP IEA Rattus norvegicus 58165 R-RNO-418553 https://reactome.org/PathwayBrowser/#/R-RNO-418553 cAMP degradation by Phosphodiesterases IEA Rattus norvegicus 58165 R-RNO-446974 https://reactome.org/PathwayBrowser/#/R-RNO-446974 cAMP Induces dissociation of active protein kinase A subunits from the PKA:Akap150:Iqgap1 complex TAS Rattus norvegicus 58165 R-RNO-5610727 https://reactome.org/PathwayBrowser/#/R-RNO-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Rattus norvegicus 58165 R-RNO-5610749 https://reactome.org/PathwayBrowser/#/R-RNO-5610749 cAMP dissociates PKA, promoting GLI processing IEA Rattus norvegicus 58165 R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 58165 R-RNO-8951727 https://reactome.org/PathwayBrowser/#/R-RNO-8951727 cAMP binds PKA tetramer IEA Rattus norvegicus 58165 R-RNO-9617504 https://reactome.org/PathwayBrowser/#/R-RNO-9617504 Calmodulin-activated adenylate cyclases Adcy1 and Adcy8 generate cAMP TAS Rattus norvegicus 58165 R-RNO-9629675 https://reactome.org/PathwayBrowser/#/R-RNO-9629675 PDE3A hydrolyses cAMP to AMP IEA Rattus norvegicus 58165 R-RNO-9644869 https://reactome.org/PathwayBrowser/#/R-RNO-9644869 p-S54-PDE4B hydrolyses cAMP IEA Rattus norvegicus 58165 R-RNO-9705507 https://reactome.org/PathwayBrowser/#/R-RNO-9705507 PDE3B hydrolyses cAMP to AMP IEA Rattus norvegicus 58165 R-RNO-9708261 https://reactome.org/PathwayBrowser/#/R-RNO-9708261 PDE4A hydrolyses cAMP to AMP IEA Rattus norvegicus 58165 R-RNO-9713673 https://reactome.org/PathwayBrowser/#/R-RNO-9713673 cAMP binds the olfactory CNG channel TAS Rattus norvegicus 58165 R-RNO-9713735 https://reactome.org/PathwayBrowser/#/R-RNO-9713735 Adcy3:Gnal:GTP converts ATP to cAMP TAS Rattus norvegicus 58165 R-RNO-9713740 https://reactome.org/PathwayBrowser/#/R-RNO-9713740 cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol TAS Rattus norvegicus 58165 R-RNO-9726875 https://reactome.org/PathwayBrowser/#/R-RNO-9726875 HCNs:cAMP bind SNIs IEA Rattus norvegicus 58165 R-SCE-111925 https://reactome.org/PathwayBrowser/#/R-SCE-111925 cAMP induces dissociation of inactive PKA tetramers IEA Saccharomyces cerevisiae 58165 R-SCE-381608 https://reactome.org/PathwayBrowser/#/R-SCE-381608 cAMP activates EPAC2 IEA Saccharomyces cerevisiae 58165 R-SCE-381668 https://reactome.org/PathwayBrowser/#/R-SCE-381668 cAMP activates EPAC1 IEA Saccharomyces cerevisiae 58165 R-SCE-381727 https://reactome.org/PathwayBrowser/#/R-SCE-381727 RAP1A exchanges GDP for GTP IEA Saccharomyces cerevisiae 58165 R-SCE-392834 https://reactome.org/PathwayBrowser/#/R-SCE-392834 Activation of EPACs by cAMP IEA Saccharomyces cerevisiae 58165 R-SCE-5610749 https://reactome.org/PathwayBrowser/#/R-SCE-5610749 cAMP dissociates PKA, promoting GLI processing IEA Saccharomyces cerevisiae 58165 R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 58165 R-SCE-8951727 https://reactome.org/PathwayBrowser/#/R-SCE-8951727 cAMP binds PKA tetramer IEA Saccharomyces cerevisiae 58165 R-SPO-111925 https://reactome.org/PathwayBrowser/#/R-SPO-111925 cAMP induces dissociation of inactive PKA tetramers IEA Schizosaccharomyces pombe 58165 R-SPO-381608 https://reactome.org/PathwayBrowser/#/R-SPO-381608 cAMP activates EPAC2 IEA Schizosaccharomyces pombe 58165 R-SPO-381668 https://reactome.org/PathwayBrowser/#/R-SPO-381668 cAMP activates EPAC1 IEA Schizosaccharomyces pombe 58165 R-SPO-392834 https://reactome.org/PathwayBrowser/#/R-SPO-392834 Activation of EPACs by cAMP IEA Schizosaccharomyces pombe 58165 R-SPO-5610749 https://reactome.org/PathwayBrowser/#/R-SPO-5610749 cAMP dissociates PKA, promoting GLI processing IEA Schizosaccharomyces pombe 58165 R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 58165 R-SPO-8951727 https://reactome.org/PathwayBrowser/#/R-SPO-8951727 cAMP binds PKA tetramer IEA Schizosaccharomyces pombe 58165 R-SSC-111925 https://reactome.org/PathwayBrowser/#/R-SSC-111925 cAMP induces dissociation of inactive PKA tetramers IEA Sus scrofa 58165 R-SSC-111930 https://reactome.org/PathwayBrowser/#/R-SSC-111930 Adenylate cyclase produces cAMP IEA Sus scrofa 58165 R-SSC-111955 https://reactome.org/PathwayBrowser/#/R-SSC-111955 cAMP hydrolysis by Cam-PDE 1 IEA Sus scrofa 58165 R-SSC-111962 https://reactome.org/PathwayBrowser/#/R-SSC-111962 PDE4A,C,D hydrolyse cAMP IEA Sus scrofa 58165 R-SSC-1296043 https://reactome.org/PathwayBrowser/#/R-SSC-1296043 Activation of HCN channels IEA Sus scrofa 58165 R-SSC-1297444 https://reactome.org/PathwayBrowser/#/R-SSC-1297444 Binding of cAMP to HCN channels IEA Sus scrofa 58165 R-SSC-162425 https://reactome.org/PathwayBrowser/#/R-SSC-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Sus scrofa 58165 R-SSC-170676 https://reactome.org/PathwayBrowser/#/R-SSC-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Sus scrofa 58165 R-SSC-265682 https://reactome.org/PathwayBrowser/#/R-SSC-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Sus scrofa 58165 R-SSC-381608 https://reactome.org/PathwayBrowser/#/R-SSC-381608 cAMP activates EPAC2 IEA Sus scrofa 58165 R-SSC-381668 https://reactome.org/PathwayBrowser/#/R-SSC-381668 cAMP activates EPAC1 IEA Sus scrofa 58165 R-SSC-381727 https://reactome.org/PathwayBrowser/#/R-SSC-381727 RAP1A exchanges GDP for GTP IEA Sus scrofa 58165 R-SSC-392834 https://reactome.org/PathwayBrowser/#/R-SSC-392834 Activation of EPACs by cAMP IEA Sus scrofa 58165 R-SSC-418553 https://reactome.org/PathwayBrowser/#/R-SSC-418553 cAMP degradation by Phosphodiesterases IEA Sus scrofa 58165 R-SSC-5610727 https://reactome.org/PathwayBrowser/#/R-SSC-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Sus scrofa 58165 R-SSC-5610749 https://reactome.org/PathwayBrowser/#/R-SSC-5610749 cAMP dissociates PKA, promoting GLI processing IEA Sus scrofa 58165 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 58165 R-SSC-8951727 https://reactome.org/PathwayBrowser/#/R-SSC-8951727 cAMP binds PKA tetramer IEA Sus scrofa 58165 R-SSC-9629675 https://reactome.org/PathwayBrowser/#/R-SSC-9629675 PDE3A hydrolyses cAMP to AMP IEA Sus scrofa 58165 R-SSC-9644869 https://reactome.org/PathwayBrowser/#/R-SSC-9644869 p-S54-PDE4B hydrolyses cAMP IEA Sus scrofa 58165 R-SSC-9705507 https://reactome.org/PathwayBrowser/#/R-SSC-9705507 PDE3B hydrolyses cAMP to AMP IEA Sus scrofa 58165 R-SSC-9708261 https://reactome.org/PathwayBrowser/#/R-SSC-9708261 PDE4A hydrolyses cAMP to AMP IEA Sus scrofa 58165 R-SSC-9726875 https://reactome.org/PathwayBrowser/#/R-SSC-9726875 HCNs:cAMP bind SNIs IEA Sus scrofa 58165 R-XTR-111925 https://reactome.org/PathwayBrowser/#/R-XTR-111925 cAMP induces dissociation of inactive PKA tetramers IEA Xenopus tropicalis 58165 R-XTR-111930 https://reactome.org/PathwayBrowser/#/R-XTR-111930 Adenylate cyclase produces cAMP IEA Xenopus tropicalis 58165 R-XTR-111955 https://reactome.org/PathwayBrowser/#/R-XTR-111955 cAMP hydrolysis by Cam-PDE 1 IEA Xenopus tropicalis 58165 R-XTR-111962 https://reactome.org/PathwayBrowser/#/R-XTR-111962 PDE4A,C,D hydrolyse cAMP IEA Xenopus tropicalis 58165 R-XTR-1296043 https://reactome.org/PathwayBrowser/#/R-XTR-1296043 Activation of HCN channels IEA Xenopus tropicalis 58165 R-XTR-1297444 https://reactome.org/PathwayBrowser/#/R-XTR-1297444 Binding of cAMP to HCN channels IEA Xenopus tropicalis 58165 R-XTR-162425 https://reactome.org/PathwayBrowser/#/R-XTR-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Xenopus tropicalis 58165 R-XTR-170676 https://reactome.org/PathwayBrowser/#/R-XTR-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Xenopus tropicalis 58165 R-XTR-265682 https://reactome.org/PathwayBrowser/#/R-XTR-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Xenopus tropicalis 58165 R-XTR-381608 https://reactome.org/PathwayBrowser/#/R-XTR-381608 cAMP activates EPAC2 IEA Xenopus tropicalis 58165 R-XTR-381668 https://reactome.org/PathwayBrowser/#/R-XTR-381668 cAMP activates EPAC1 IEA Xenopus tropicalis 58165 R-XTR-381727 https://reactome.org/PathwayBrowser/#/R-XTR-381727 RAP1A exchanges GDP for GTP IEA Xenopus tropicalis 58165 R-XTR-392834 https://reactome.org/PathwayBrowser/#/R-XTR-392834 Activation of EPACs by cAMP IEA Xenopus tropicalis 58165 R-XTR-418553 https://reactome.org/PathwayBrowser/#/R-XTR-418553 cAMP degradation by Phosphodiesterases IEA Xenopus tropicalis 58165 R-XTR-5610727 https://reactome.org/PathwayBrowser/#/R-XTR-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Xenopus tropicalis 58165 R-XTR-5610749 https://reactome.org/PathwayBrowser/#/R-XTR-5610749 cAMP dissociates PKA, promoting GLI processing IEA Xenopus tropicalis 58165 R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 58165 R-XTR-8951727 https://reactome.org/PathwayBrowser/#/R-XTR-8951727 cAMP binds PKA tetramer IEA Xenopus tropicalis 58165 R-XTR-9644869 https://reactome.org/PathwayBrowser/#/R-XTR-9644869 p-S54-PDE4B hydrolyses cAMP IEA Xenopus tropicalis 58165 R-XTR-9705507 https://reactome.org/PathwayBrowser/#/R-XTR-9705507 PDE3B hydrolyses cAMP to AMP IEA Xenopus tropicalis 58165 R-XTR-9708261 https://reactome.org/PathwayBrowser/#/R-XTR-9708261 PDE4A hydrolyses cAMP to AMP IEA Xenopus tropicalis 58165 R-XTR-9726875 https://reactome.org/PathwayBrowser/#/R-XTR-9726875 HCNs:cAMP bind SNIs IEA Xenopus tropicalis 58168 R-BTA-6814254 https://reactome.org/PathwayBrowser/#/R-BTA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Bos taurus 58168 R-BTA-8858298 https://reactome.org/PathwayBrowser/#/R-BTA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Bos taurus 58168 R-CEL-6814254 https://reactome.org/PathwayBrowser/#/R-CEL-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Caenorhabditis elegans 58168 R-CFA-6814254 https://reactome.org/PathwayBrowser/#/R-CFA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Canis familiaris 58168 R-CFA-8858298 https://reactome.org/PathwayBrowser/#/R-CFA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Canis familiaris 58168 R-DME-6814254 https://reactome.org/PathwayBrowser/#/R-DME-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Drosophila melanogaster 58168 R-DRE-8858298 https://reactome.org/PathwayBrowser/#/R-DRE-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Danio rerio 58168 R-GGA-6814254 https://reactome.org/PathwayBrowser/#/R-GGA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Gallus gallus 58168 R-HSA-6814254 https://reactome.org/PathwayBrowser/#/R-HSA-6814254 PNPLA6 hydrolyzes LysoPtdCho TAS Homo sapiens 58168 R-HSA-6814766 https://reactome.org/PathwayBrowser/#/R-HSA-6814766 GDPD1 hydrolyzes LysoPtdCho IEA Homo sapiens 58168 R-HSA-6814778 https://reactome.org/PathwayBrowser/#/R-HSA-6814778 GDPD3 hydrolyzes LysoPtdCho IEA Homo sapiens 58168 R-HSA-8847912 https://reactome.org/PathwayBrowser/#/R-HSA-8847912 PNPLA7 hydrolyzes LysoPtdCho IEA Homo sapiens 58168 R-HSA-8858298 https://reactome.org/PathwayBrowser/#/R-HSA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE TAS Homo sapiens 58168 R-MMU-6814254 https://reactome.org/PathwayBrowser/#/R-MMU-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Mus musculus 58168 R-MMU-8847424 https://reactome.org/PathwayBrowser/#/R-MMU-8847424 Gdpd1 hydrolyzes LysoPtdCho TAS Mus musculus 58168 R-MMU-8847427 https://reactome.org/PathwayBrowser/#/R-MMU-8847427 Gdpd3 hydrolyzes LysoPtdCho TAS Mus musculus 58168 R-MMU-8847904 https://reactome.org/PathwayBrowser/#/R-MMU-8847904 Pnpla7 hydrolyzes LysoPtdCho TAS Mus musculus 58168 R-MMU-8858298 https://reactome.org/PathwayBrowser/#/R-MMU-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Mus musculus 58168 R-RNO-6814254 https://reactome.org/PathwayBrowser/#/R-RNO-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Rattus norvegicus 58168 R-RNO-8858298 https://reactome.org/PathwayBrowser/#/R-RNO-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Rattus norvegicus 58168 R-SCE-6814254 https://reactome.org/PathwayBrowser/#/R-SCE-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Saccharomyces cerevisiae 58168 R-SPO-6814254 https://reactome.org/PathwayBrowser/#/R-SPO-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Schizosaccharomyces pombe 58168 R-SSC-6814254 https://reactome.org/PathwayBrowser/#/R-SSC-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Sus scrofa 58168 R-SSC-8858298 https://reactome.org/PathwayBrowser/#/R-SSC-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Sus scrofa 58168 R-XTR-8858298 https://reactome.org/PathwayBrowser/#/R-XTR-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Xenopus tropicalis 58173 R-BTA-1247922 https://reactome.org/PathwayBrowser/#/R-BTA-1247922 GGCT transforms gGluCys to OPRO IEA Bos taurus 58173 R-BTA-174367 https://reactome.org/PathwayBrowser/#/R-BTA-174367 GCL ligates L-Glu to L-Cys IEA Bos taurus 58173 R-BTA-174394 https://reactome.org/PathwayBrowser/#/R-BTA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Bos taurus 58173 R-CEL-1247922 https://reactome.org/PathwayBrowser/#/R-CEL-1247922 GGCT transforms gGluCys to OPRO IEA Caenorhabditis elegans 58173 R-CEL-174367 https://reactome.org/PathwayBrowser/#/R-CEL-174367 GCL ligates L-Glu to L-Cys IEA Caenorhabditis elegans 58173 R-CEL-174394 https://reactome.org/PathwayBrowser/#/R-CEL-174394 GSS:Mg2+ dimer synthesizes GSH IEA Caenorhabditis elegans 58173 R-CFA-1247922 https://reactome.org/PathwayBrowser/#/R-CFA-1247922 GGCT transforms gGluCys to OPRO IEA Canis familiaris 58173 R-CFA-174367 https://reactome.org/PathwayBrowser/#/R-CFA-174367 GCL ligates L-Glu to L-Cys IEA Canis familiaris 58173 R-CFA-174394 https://reactome.org/PathwayBrowser/#/R-CFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Canis familiaris 58173 R-DDI-174394 https://reactome.org/PathwayBrowser/#/R-DDI-174394 GSS:Mg2+ dimer synthesizes GSH IEA Dictyostelium discoideum 58173 R-DME-1247922 https://reactome.org/PathwayBrowser/#/R-DME-1247922 GGCT transforms gGluCys to OPRO IEA Drosophila melanogaster 58173 R-DME-174367 https://reactome.org/PathwayBrowser/#/R-DME-174367 GCL ligates L-Glu to L-Cys IEA Drosophila melanogaster 58173 R-DME-174394 https://reactome.org/PathwayBrowser/#/R-DME-174394 GSS:Mg2+ dimer synthesizes GSH IEA Drosophila melanogaster 58173 R-DRE-1247922 https://reactome.org/PathwayBrowser/#/R-DRE-1247922 GGCT transforms gGluCys to OPRO IEA Danio rerio 58173 R-DRE-174394 https://reactome.org/PathwayBrowser/#/R-DRE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Danio rerio 58173 R-GGA-1247922 https://reactome.org/PathwayBrowser/#/R-GGA-1247922 GGCT transforms gGluCys to OPRO IEA Gallus gallus 58173 R-GGA-174394 https://reactome.org/PathwayBrowser/#/R-GGA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Gallus gallus 58173 R-HSA-1247922 https://reactome.org/PathwayBrowser/#/R-HSA-1247922 GGCT transforms gGluCys to OPRO TAS Homo sapiens 58173 R-HSA-174367 https://reactome.org/PathwayBrowser/#/R-HSA-174367 GCL ligates L-Glu to L-Cys TAS Homo sapiens 58173 R-HSA-174394 https://reactome.org/PathwayBrowser/#/R-HSA-174394 GSS:Mg2+ dimer synthesizes GSH TAS Homo sapiens 58173 R-HSA-5602901 https://reactome.org/PathwayBrowser/#/R-HSA-5602901 Defective GSS does not synthesize GSH TAS Homo sapiens 58173 R-MMU-1247922 https://reactome.org/PathwayBrowser/#/R-MMU-1247922 GGCT transforms gGluCys to OPRO IEA Mus musculus 58173 R-MMU-174367 https://reactome.org/PathwayBrowser/#/R-MMU-174367 GCL ligates L-Glu to L-Cys IEA Mus musculus 58173 R-MMU-174394 https://reactome.org/PathwayBrowser/#/R-MMU-174394 GSS:Mg2+ dimer synthesizes GSH IEA Mus musculus 58173 R-PFA-174394 https://reactome.org/PathwayBrowser/#/R-PFA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Plasmodium falciparum 58173 R-RNO-1247922 https://reactome.org/PathwayBrowser/#/R-RNO-1247922 GGCT transforms gGluCys to OPRO IEA Rattus norvegicus 58173 R-RNO-174367 https://reactome.org/PathwayBrowser/#/R-RNO-174367 GCL ligates L-Glu to L-Cys IEA Rattus norvegicus 58173 R-RNO-174394 https://reactome.org/PathwayBrowser/#/R-RNO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Rattus norvegicus 58173 R-SCE-174394 https://reactome.org/PathwayBrowser/#/R-SCE-174394 GSS:Mg2+ dimer synthesizes GSH IEA Saccharomyces cerevisiae 58173 R-SPO-174367 https://reactome.org/PathwayBrowser/#/R-SPO-174367 GCL ligates L-Glu to L-Cys IEA Schizosaccharomyces pombe 58173 R-SPO-174394 https://reactome.org/PathwayBrowser/#/R-SPO-174394 GSS:Mg2+ dimer synthesizes GSH IEA Schizosaccharomyces pombe 58173 R-SSC-1247922 https://reactome.org/PathwayBrowser/#/R-SSC-1247922 GGCT transforms gGluCys to OPRO IEA Sus scrofa 58173 R-SSC-174367 https://reactome.org/PathwayBrowser/#/R-SSC-174367 GCL ligates L-Glu to L-Cys IEA Sus scrofa 58173 R-SSC-174394 https://reactome.org/PathwayBrowser/#/R-SSC-174394 GSS:Mg2+ dimer synthesizes GSH IEA Sus scrofa 58173 R-XTR-1247922 https://reactome.org/PathwayBrowser/#/R-XTR-1247922 GGCT transforms gGluCys to OPRO IEA Xenopus tropicalis 58173 R-XTR-174367 https://reactome.org/PathwayBrowser/#/R-XTR-174367 GCL ligates L-Glu to L-Cys IEA Xenopus tropicalis 58189 R-BTA-1008248 https://reactome.org/PathwayBrowser/#/R-BTA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Bos taurus 58189 R-BTA-1028788 https://reactome.org/PathwayBrowser/#/R-BTA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Bos taurus 58189 R-BTA-110133 https://reactome.org/PathwayBrowser/#/R-BTA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Bos taurus 58189 R-BTA-111524 https://reactome.org/PathwayBrowser/#/R-BTA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Bos taurus 58189 R-BTA-112037 https://reactome.org/PathwayBrowser/#/R-BTA-112037 Inactivation of PLC beta IEA Bos taurus 58189 R-BTA-114544 https://reactome.org/PathwayBrowser/#/R-BTA-114544 p115-RhoGEF activation of RHOA IEA Bos taurus 58189 R-BTA-114552 https://reactome.org/PathwayBrowser/#/R-BTA-114552 Thrombin-activated PARs activate G12/13 IEA Bos taurus 58189 R-BTA-114558 https://reactome.org/PathwayBrowser/#/R-BTA-114558 Thrombin-activated PARs activate Gq IEA Bos taurus 58189 R-BTA-1168636 https://reactome.org/PathwayBrowser/#/R-BTA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Bos taurus 58189 R-BTA-1250383 https://reactome.org/PathwayBrowser/#/R-BTA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Bos taurus 58189 R-BTA-1306972 https://reactome.org/PathwayBrowser/#/R-BTA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Bos taurus 58189 R-BTA-1433415 https://reactome.org/PathwayBrowser/#/R-BTA-1433415 Activation of RAC1 IEA Bos taurus 58189 R-BTA-1433471 https://reactome.org/PathwayBrowser/#/R-BTA-1433471 Activation of RAS by p-KIT bound SOS1 IEA Bos taurus 58189 R-BTA-156913 https://reactome.org/PathwayBrowser/#/R-BTA-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Bos taurus 58189 R-BTA-162721 https://reactome.org/PathwayBrowser/#/R-BTA-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Bos taurus 58189 R-BTA-1638803 https://reactome.org/PathwayBrowser/#/R-BTA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Bos taurus 58189 R-BTA-1638821 https://reactome.org/PathwayBrowser/#/R-BTA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Bos taurus 58189 R-BTA-165195 https://reactome.org/PathwayBrowser/#/R-BTA-165195 GTP loading by Rheb IEA Bos taurus 58189 R-BTA-165680 https://reactome.org/PathwayBrowser/#/R-BTA-165680 Formation of active mTORC1 complex IEA Bos taurus 58189 R-BTA-165692 https://reactome.org/PathwayBrowser/#/R-BTA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Bos taurus 58189 R-BTA-165718 https://reactome.org/PathwayBrowser/#/R-BTA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Bos taurus 58189 R-BTA-167408 https://reactome.org/PathwayBrowser/#/R-BTA-167408 The high affinity receptor complex binds to G-protein IEA Bos taurus 58189 R-BTA-167415 https://reactome.org/PathwayBrowser/#/R-BTA-167415 G-protein alpha subunit is inactivated IEA Bos taurus 58189 R-BTA-167419 https://reactome.org/PathwayBrowser/#/R-BTA-167419 The receptor:G-protein complex releases GDP IEA Bos taurus 58189 R-BTA-167433 https://reactome.org/PathwayBrowser/#/R-BTA-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Bos taurus 58189 R-BTA-169904 https://reactome.org/PathwayBrowser/#/R-BTA-169904 C3G stimulates nucleotide exchange on Rap1 IEA Bos taurus 58189 R-BTA-170026 https://reactome.org/PathwayBrowser/#/R-BTA-170026 Protons are translocated from the intermembrane space to the matrix IEA Bos taurus 58189 R-BTA-170666 https://reactome.org/PathwayBrowser/#/R-BTA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Bos taurus 58189 R-BTA-170674 https://reactome.org/PathwayBrowser/#/R-BTA-170674 Dissociation of the Gi alpha:G olf complex IEA Bos taurus 58189 R-BTA-170677 https://reactome.org/PathwayBrowser/#/R-BTA-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Bos taurus 58189 R-BTA-170685 https://reactome.org/PathwayBrowser/#/R-BTA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Bos taurus 58189 R-BTA-170686 https://reactome.org/PathwayBrowser/#/R-BTA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Bos taurus 58189 R-BTA-177938 https://reactome.org/PathwayBrowser/#/R-BTA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Bos taurus 58189 R-BTA-177945 https://reactome.org/PathwayBrowser/#/R-BTA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Bos taurus 58189 R-BTA-186834 https://reactome.org/PathwayBrowser/#/R-BTA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Bos taurus 58189 R-BTA-190520 https://reactome.org/PathwayBrowser/#/R-BTA-190520 Association of Golgi transport vesicles with microtubules IEA Bos taurus 58189 R-BTA-193646 https://reactome.org/PathwayBrowser/#/R-BTA-193646 NGF binding to p75NTR inactivates RHOA IEA Bos taurus 58189 R-BTA-193668 https://reactome.org/PathwayBrowser/#/R-BTA-193668 p75NTR and RHOA-GDI interact IEA Bos taurus 58189 R-BTA-193696 https://reactome.org/PathwayBrowser/#/R-BTA-193696 The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA IEA Bos taurus 58189 R-BTA-194518 https://reactome.org/PathwayBrowser/#/R-BTA-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Bos taurus 58189 R-BTA-2029451 https://reactome.org/PathwayBrowser/#/R-BTA-2029451 Activation of RAC1 by VAV IEA Bos taurus 58189 R-BTA-2029467 https://reactome.org/PathwayBrowser/#/R-BTA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Bos taurus 58189 R-BTA-203977 https://reactome.org/PathwayBrowser/#/R-BTA-203977 SAR1 Activation And Membrane Binding IEA Bos taurus 58189 R-BTA-205039 https://reactome.org/PathwayBrowser/#/R-BTA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Bos taurus 58189 R-BTA-210977 https://reactome.org/PathwayBrowser/#/R-BTA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Bos taurus 58189 R-BTA-2130641 https://reactome.org/PathwayBrowser/#/R-BTA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Bos taurus 58189 R-BTA-2130725 https://reactome.org/PathwayBrowser/#/R-BTA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Bos taurus 58189 R-BTA-2179407 https://reactome.org/PathwayBrowser/#/R-BTA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Bos taurus 58189 R-BTA-2213248 https://reactome.org/PathwayBrowser/#/R-BTA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Bos taurus 58189 R-BTA-2424476 https://reactome.org/PathwayBrowser/#/R-BTA-2424476 Activation of RAC1 by VAV2/3 IEA Bos taurus 58189 R-BTA-2424477 https://reactome.org/PathwayBrowser/#/R-BTA-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Bos taurus 58189 R-BTA-2467809 https://reactome.org/PathwayBrowser/#/R-BTA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Bos taurus 58189 R-BTA-2467811 https://reactome.org/PathwayBrowser/#/R-BTA-2467811 Separation of sister chromatids IEA Bos taurus 58189 R-BTA-2468287 https://reactome.org/PathwayBrowser/#/R-BTA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Bos taurus 58189 R-BTA-2484822 https://reactome.org/PathwayBrowser/#/R-BTA-2484822 Kinetochore assembly IEA Bos taurus 58189 R-BTA-2530504 https://reactome.org/PathwayBrowser/#/R-BTA-2530504 MII catalyses GDP/GTP exchange on Gt TAS Bos taurus 58189 R-BTA-2584246 https://reactome.org/PathwayBrowser/#/R-BTA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Bos taurus 58189 R-BTA-2730840 https://reactome.org/PathwayBrowser/#/R-BTA-2730840 Activation of RAC1 by VAV IEA Bos taurus 58189 R-BTA-3229197 https://reactome.org/PathwayBrowser/#/R-BTA-3229197 Gnat1-GDP binds to Gnb1:Gngt1 TAS Bos taurus 58189 R-BTA-350769 https://reactome.org/PathwayBrowser/#/R-BTA-350769 trans-Golgi Network Coat Activation IEA Bos taurus 58189 R-BTA-354173 https://reactome.org/PathwayBrowser/#/R-BTA-354173 Activation of Rap1 by cytosolic GEFs IEA Bos taurus 58189 R-BTA-372819 https://reactome.org/PathwayBrowser/#/R-BTA-372819 PCK2 phosphorylates OA to yield PEP IEA Bos taurus 58189 R-BTA-375302 https://reactome.org/PathwayBrowser/#/R-BTA-375302 Kinetochore capture of astral microtubules IEA Bos taurus 58189 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 58189 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 58189 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 58189 R-BTA-380316 https://reactome.org/PathwayBrowser/#/R-BTA-380316 Association of NuMA with microtubules IEA Bos taurus 58189 R-BTA-380979 https://reactome.org/PathwayBrowser/#/R-BTA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Bos taurus 58189 R-BTA-381612 https://reactome.org/PathwayBrowser/#/R-BTA-381612 GLP1R binds GLP1 IEA Bos taurus 58189 R-BTA-381727 https://reactome.org/PathwayBrowser/#/R-BTA-381727 RAP1A exchanges GDP for GTP IEA Bos taurus 58189 R-BTA-389348 https://reactome.org/PathwayBrowser/#/R-BTA-389348 Activation of Rac1 by pVav1 IEA Bos taurus 58189 R-BTA-389350 https://reactome.org/PathwayBrowser/#/R-BTA-389350 Activation of Cdc42 by pVav1 IEA Bos taurus 58189 R-BTA-392054 https://reactome.org/PathwayBrowser/#/R-BTA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Bos taurus 58189 R-BTA-392195 https://reactome.org/PathwayBrowser/#/R-BTA-392195 Gi activation by P2Y purinoceptor 12 IEA Bos taurus 58189 R-BTA-392513 https://reactome.org/PathwayBrowser/#/R-BTA-392513 Rap1 signal termination by Rap1GAPs IEA Bos taurus 58189 R-BTA-3928592 https://reactome.org/PathwayBrowser/#/R-BTA-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Bos taurus 58189 R-BTA-3928628 https://reactome.org/PathwayBrowser/#/R-BTA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Bos taurus 58189 R-BTA-3928642 https://reactome.org/PathwayBrowser/#/R-BTA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Bos taurus 58189 R-BTA-3928651 https://reactome.org/PathwayBrowser/#/R-BTA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Bos taurus 58189 R-BTA-392870 https://reactome.org/PathwayBrowser/#/R-BTA-392870 Gs activation by prostacyclin receptor IEA Bos taurus 58189 R-BTA-3965444 https://reactome.org/PathwayBrowser/#/R-BTA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Bos taurus 58189 R-BTA-400092 https://reactome.org/PathwayBrowser/#/R-BTA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Bos taurus 58189 R-BTA-4093339 https://reactome.org/PathwayBrowser/#/R-BTA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Bos taurus 58189 R-BTA-416530 https://reactome.org/PathwayBrowser/#/R-BTA-416530 FFAR1:FFAR1 ligands activate Gq IEA Bos taurus 58189 R-BTA-416559 https://reactome.org/PathwayBrowser/#/R-BTA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Bos taurus 58189 R-BTA-416588 https://reactome.org/PathwayBrowser/#/R-BTA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Bos taurus 58189 R-BTA-418850 https://reactome.org/PathwayBrowser/#/R-BTA-418850 Activation of Cdc42 IEA Bos taurus 58189 R-BTA-418856 https://reactome.org/PathwayBrowser/#/R-BTA-418856 Activation of Rac1 IEA Bos taurus 58189 R-BTA-419166 https://reactome.org/PathwayBrowser/#/R-BTA-419166 GEFs activate RhoA,B,C IEA Bos taurus 58189 R-BTA-420883 https://reactome.org/PathwayBrowser/#/R-BTA-420883 Opsins act as GEFs for G alpha-t IEA Bos taurus 58189 R-BTA-421831 https://reactome.org/PathwayBrowser/#/R-BTA-421831 trans-Golgi Network Coat Assembly IEA Bos taurus 58189 R-BTA-421835 https://reactome.org/PathwayBrowser/#/R-BTA-421835 trans-Golgi Network Vesicle Scission IEA Bos taurus 58189 R-BTA-428750 https://reactome.org/PathwayBrowser/#/R-BTA-428750 Gq activation by TP receptor IEA Bos taurus 58189 R-BTA-428917 https://reactome.org/PathwayBrowser/#/R-BTA-428917 G13 activation by TP receptor IEA Bos taurus 58189 R-BTA-432195 https://reactome.org/PathwayBrowser/#/R-BTA-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Bos taurus 58189 R-BTA-432706 https://reactome.org/PathwayBrowser/#/R-BTA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Bos taurus 58189 R-BTA-432707 https://reactome.org/PathwayBrowser/#/R-BTA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Bos taurus 58189 R-BTA-442273 https://reactome.org/PathwayBrowser/#/R-BTA-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Bos taurus 58189 R-BTA-442291 https://reactome.org/PathwayBrowser/#/R-BTA-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Bos taurus 58189 R-BTA-442314 https://reactome.org/PathwayBrowser/#/R-BTA-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Bos taurus 58189 R-BTA-445064 https://reactome.org/PathwayBrowser/#/R-BTA-445064 Activation of Rac1 by VAV2 IEA Bos taurus 58189 R-BTA-446208 https://reactome.org/PathwayBrowser/#/R-BTA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Bos taurus 58189 R-BTA-446218 https://reactome.org/PathwayBrowser/#/R-BTA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Bos taurus 58189 R-BTA-447074 https://reactome.org/PathwayBrowser/#/R-BTA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Bos taurus 58189 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 58189 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 58189 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 58189 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 58189 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 58189 R-BTA-5218839 https://reactome.org/PathwayBrowser/#/R-BTA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Bos taurus 58189 R-BTA-5218850 https://reactome.org/PathwayBrowser/#/R-BTA-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Bos taurus 58189 R-BTA-5419271 https://reactome.org/PathwayBrowser/#/R-BTA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Bos taurus 58189 R-BTA-5419273 https://reactome.org/PathwayBrowser/#/R-BTA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Bos taurus 58189 R-BTA-5432388 https://reactome.org/PathwayBrowser/#/R-BTA-5432388 TUFM:GDP dissociates from 55S ribosome TAS Bos taurus 58189 R-BTA-5432421 https://reactome.org/PathwayBrowser/#/R-BTA-5432421 39S subunit binds 28S subunit:mRNA:fMet-tRNA TAS Bos taurus 58189 R-BTA-5432422 https://reactome.org/PathwayBrowser/#/R-BTA-5432422 Translocation of 55S ribosome by 3 bases in the 3' direction TAS Bos taurus 58189 R-BTA-5432536 https://reactome.org/PathwayBrowser/#/R-BTA-5432536 TSFM binds TUFM displacing GDP TAS Bos taurus 58189 R-BTA-555065 https://reactome.org/PathwayBrowser/#/R-BTA-555065 Formation of clathrin coated vesicle IEA Bos taurus 58189 R-BTA-5610733 https://reactome.org/PathwayBrowser/#/R-BTA-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Bos taurus 58189 R-BTA-5610767 https://reactome.org/PathwayBrowser/#/R-BTA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Bos taurus 58189 R-BTA-5617816 https://reactome.org/PathwayBrowser/#/R-BTA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Bos taurus 58189 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 58189 R-BTA-5618328 https://reactome.org/PathwayBrowser/#/R-BTA-5618328 ATAT acetylates microtubules IEA Bos taurus 58189 R-BTA-5618331 https://reactome.org/PathwayBrowser/#/R-BTA-5618331 HDAC6 deacetylates microtubules IEA Bos taurus 58189 R-BTA-5623508 https://reactome.org/PathwayBrowser/#/R-BTA-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Bos taurus 58189 R-BTA-5623513 https://reactome.org/PathwayBrowser/#/R-BTA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Bos taurus 58189 R-BTA-5623519 https://reactome.org/PathwayBrowser/#/R-BTA-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Bos taurus 58189 R-BTA-5623521 https://reactome.org/PathwayBrowser/#/R-BTA-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Bos taurus 58189 R-BTA-5624949 https://reactome.org/PathwayBrowser/#/R-BTA-5624949 Assembly of the anterograde IFT train IEA Bos taurus 58189 R-BTA-5625416 https://reactome.org/PathwayBrowser/#/R-BTA-5625416 Anterograde IFT IEA Bos taurus 58189 R-BTA-5625426 https://reactome.org/PathwayBrowser/#/R-BTA-5625426 Retrograde IFT IEA Bos taurus 58189 R-BTA-5653957 https://reactome.org/PathwayBrowser/#/R-BTA-5653957 Rag dimer formation IEA Bos taurus 58189 R-BTA-5653968 https://reactome.org/PathwayBrowser/#/R-BTA-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Bos taurus 58189 R-BTA-5653974 https://reactome.org/PathwayBrowser/#/R-BTA-5653974 Ragulator binds Rag dimers IEA Bos taurus 58189 R-BTA-5654392 https://reactome.org/PathwayBrowser/#/R-BTA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-5654402 https://reactome.org/PathwayBrowser/#/R-BTA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-5654413 https://reactome.org/PathwayBrowser/#/R-BTA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-5654426 https://reactome.org/PathwayBrowser/#/R-BTA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-5654600 https://reactome.org/PathwayBrowser/#/R-BTA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-5654618 https://reactome.org/PathwayBrowser/#/R-BTA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-5654647 https://reactome.org/PathwayBrowser/#/R-BTA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-5654663 https://reactome.org/PathwayBrowser/#/R-BTA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-5665809 https://reactome.org/PathwayBrowser/#/R-BTA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Bos taurus 58189 R-BTA-5666169 https://reactome.org/PathwayBrowser/#/R-BTA-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Bos taurus 58189 R-BTA-5672010 https://reactome.org/PathwayBrowser/#/R-BTA-5672010 Active MTORC1 phosphorylates ULK1 IEA Bos taurus 58189 R-BTA-5672017 https://reactome.org/PathwayBrowser/#/R-BTA-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Bos taurus 58189 R-BTA-5672329 https://reactome.org/PathwayBrowser/#/R-BTA-5672329 IQGAP1 binds CLIP1 and microtubules IEA Bos taurus 58189 R-BTA-5672817 https://reactome.org/PathwayBrowser/#/R-BTA-5672817 Active MTORC1 binds the ULK1 complex IEA Bos taurus 58189 R-BTA-5672824 https://reactome.org/PathwayBrowser/#/R-BTA-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Bos taurus 58189 R-BTA-5672828 https://reactome.org/PathwayBrowser/#/R-BTA-5672828 mTORC1 phosphorylates AKT1S1 IEA Bos taurus 58189 R-BTA-5672843 https://reactome.org/PathwayBrowser/#/R-BTA-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Bos taurus 58189 R-BTA-5672965 https://reactome.org/PathwayBrowser/#/R-BTA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-5673768 https://reactome.org/PathwayBrowser/#/R-BTA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Bos taurus 58189 R-BTA-5675790 https://reactome.org/PathwayBrowser/#/R-BTA-5675790 MTORC1 dissociates from ULK complex IEA Bos taurus 58189 R-BTA-5693925 https://reactome.org/PathwayBrowser/#/R-BTA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Bos taurus 58189 R-BTA-5694409 https://reactome.org/PathwayBrowser/#/R-BTA-5694409 Nucleotide exchange on RAB1 IEA Bos taurus 58189 R-BTA-5694439 https://reactome.org/PathwayBrowser/#/R-BTA-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Bos taurus 58189 R-BTA-5694527 https://reactome.org/PathwayBrowser/#/R-BTA-5694527 Loss of SAR1B GTPase IEA Bos taurus 58189 R-BTA-6788611 https://reactome.org/PathwayBrowser/#/R-BTA-6788611 HYKK phosphorylates 5HLYS IEA Bos taurus 58189 R-BTA-6807866 https://reactome.org/PathwayBrowser/#/R-BTA-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Bos taurus 58189 R-BTA-6807868 https://reactome.org/PathwayBrowser/#/R-BTA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Bos taurus 58189 R-BTA-6807877 https://reactome.org/PathwayBrowser/#/R-BTA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Bos taurus 58189 R-BTA-6809003 https://reactome.org/PathwayBrowser/#/R-BTA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Bos taurus 58189 R-BTA-6809006 https://reactome.org/PathwayBrowser/#/R-BTA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Bos taurus 58189 R-BTA-6811411 https://reactome.org/PathwayBrowser/#/R-BTA-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Bos taurus 58189 R-BTA-6811414 https://reactome.org/PathwayBrowser/#/R-BTA-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Bos taurus 58189 R-BTA-6811418 https://reactome.org/PathwayBrowser/#/R-BTA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Bos taurus 58189 R-BTA-6811423 https://reactome.org/PathwayBrowser/#/R-BTA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Bos taurus 58189 R-BTA-6811426 https://reactome.org/PathwayBrowser/#/R-BTA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Bos taurus 58189 R-BTA-6811427 https://reactome.org/PathwayBrowser/#/R-BTA-6811427 COPI vesicle uncoating at the ER IEA Bos taurus 58189 R-BTA-6811428 https://reactome.org/PathwayBrowser/#/R-BTA-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Bos taurus 58189 R-BTA-6811429 https://reactome.org/PathwayBrowser/#/R-BTA-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Bos taurus 58189 R-BTA-6814671 https://reactome.org/PathwayBrowser/#/R-BTA-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Bos taurus 58189 R-BTA-6814682 https://reactome.org/PathwayBrowser/#/R-BTA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Bos taurus 58189 R-BTA-6814833 https://reactome.org/PathwayBrowser/#/R-BTA-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Bos taurus 58189 R-BTA-70241 https://reactome.org/PathwayBrowser/#/R-BTA-70241 PCK1 phosphorylates OA to yield PEP IEA Bos taurus 58189 R-BTA-71775 https://reactome.org/PathwayBrowser/#/R-BTA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Bos taurus 58189 R-BTA-72670 https://reactome.org/PathwayBrowser/#/R-BTA-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Bos taurus 58189 R-BTA-72671 https://reactome.org/PathwayBrowser/#/R-BTA-72671 eIF5B:GTP is hydrolyzed and released IEA Bos taurus 58189 R-BTA-72722 https://reactome.org/PathwayBrowser/#/R-BTA-72722 eIF2 activation IEA Bos taurus 58189 R-BTA-73788 https://reactome.org/PathwayBrowser/#/R-BTA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Bos taurus 58189 R-BTA-749453 https://reactome.org/PathwayBrowser/#/R-BTA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Bos taurus 58189 R-BTA-751029 https://reactome.org/PathwayBrowser/#/R-BTA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Bos taurus 58189 R-BTA-8847883 https://reactome.org/PathwayBrowser/#/R-BTA-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Bos taurus 58189 R-BTA-8848618 https://reactome.org/PathwayBrowser/#/R-BTA-8848618 Activation of RAC1 by the PXN:CRK complex IEA Bos taurus 58189 R-BTA-8849082 https://reactome.org/PathwayBrowser/#/R-BTA-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Bos taurus 58189 R-BTA-8849350 https://reactome.org/PathwayBrowser/#/R-BTA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Bos taurus 58189 R-BTA-8849353 https://reactome.org/PathwayBrowser/#/R-BTA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Bos taurus 58189 R-BTA-8850040 https://reactome.org/PathwayBrowser/#/R-BTA-8850040 RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER IEA Bos taurus 58189 R-BTA-8850041 https://reactome.org/PathwayBrowser/#/R-BTA-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Bos taurus 58189 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 58189 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 58189 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 58189 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 58189 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 58189 R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 58189 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 58189 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 58189 R-BTA-8851827 https://reactome.org/PathwayBrowser/#/R-BTA-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Bos taurus 58189 R-BTA-8851877 https://reactome.org/PathwayBrowser/#/R-BTA-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Bos taurus 58189 R-BTA-8851899 https://reactome.org/PathwayBrowser/#/R-BTA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Bos taurus 58189 R-BTA-8852280 https://reactome.org/PathwayBrowser/#/R-BTA-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Bos taurus 58189 R-BTA-8852298 https://reactome.org/PathwayBrowser/#/R-BTA-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Bos taurus 58189 R-BTA-8852306 https://reactome.org/PathwayBrowser/#/R-BTA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Bos taurus 58189 R-BTA-8854173 https://reactome.org/PathwayBrowser/#/R-BTA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Bos taurus 58189 R-BTA-8854255 https://reactome.org/PathwayBrowser/#/R-BTA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Bos taurus 58189 R-BTA-8854612 https://reactome.org/PathwayBrowser/#/R-BTA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Bos taurus 58189 R-BTA-8865774 https://reactome.org/PathwayBrowser/#/R-BTA-8865774 TTLLs polyglutamylate tubulin IEA Bos taurus 58189 R-BTA-8867370 https://reactome.org/PathwayBrowser/#/R-BTA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Bos taurus 58189 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 58189 R-BTA-8868659 https://reactome.org/PathwayBrowser/#/R-BTA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Bos taurus 58189 R-BTA-8868660 https://reactome.org/PathwayBrowser/#/R-BTA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Bos taurus 58189 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 58189 R-BTA-8870466 https://reactome.org/PathwayBrowser/#/R-BTA-8870466 RGGT:CHM binds RABs IEA Bos taurus 58189 R-BTA-8870469 https://reactome.org/PathwayBrowser/#/R-BTA-8870469 RGGT geranylgeranylates RAB proteins IEA Bos taurus 58189 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 58189 R-BTA-8871194 https://reactome.org/PathwayBrowser/#/R-BTA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Bos taurus 58189 R-BTA-8875318 https://reactome.org/PathwayBrowser/#/R-BTA-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Bos taurus 58189 R-BTA-8875320 https://reactome.org/PathwayBrowser/#/R-BTA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Bos taurus 58189 R-BTA-8875568 https://reactome.org/PathwayBrowser/#/R-BTA-8875568 RAPGEF1 activates RAP1 IEA Bos taurus 58189 R-BTA-8875591 https://reactome.org/PathwayBrowser/#/R-BTA-8875591 DOCK7 activates RAC1 IEA Bos taurus 58189 R-BTA-8876188 https://reactome.org/PathwayBrowser/#/R-BTA-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Bos taurus 58189 R-BTA-8876190 https://reactome.org/PathwayBrowser/#/R-BTA-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Bos taurus 58189 R-BTA-8876191 https://reactome.org/PathwayBrowser/#/R-BTA-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Bos taurus 58189 R-BTA-8876193 https://reactome.org/PathwayBrowser/#/R-BTA-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Bos taurus 58189 R-BTA-8876454 https://reactome.org/PathwayBrowser/#/R-BTA-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Bos taurus 58189 R-BTA-8876615 https://reactome.org/PathwayBrowser/#/R-BTA-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Bos taurus 58189 R-BTA-8876616 https://reactome.org/PathwayBrowser/#/R-BTA-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Bos taurus 58189 R-BTA-8876837 https://reactome.org/PathwayBrowser/#/R-BTA-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Bos taurus 58189 R-BTA-8877308 https://reactome.org/PathwayBrowser/#/R-BTA-8877308 MADD exchanges GTP for GDP on RAB27 IEA Bos taurus 58189 R-BTA-8877311 https://reactome.org/PathwayBrowser/#/R-BTA-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Bos taurus 58189 R-BTA-8877451 https://reactome.org/PathwayBrowser/#/R-BTA-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Bos taurus 58189 R-BTA-8877475 https://reactome.org/PathwayBrowser/#/R-BTA-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Bos taurus 58189 R-BTA-8877612 https://reactome.org/PathwayBrowser/#/R-BTA-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Bos taurus 58189 R-BTA-8877760 https://reactome.org/PathwayBrowser/#/R-BTA-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Bos taurus 58189 R-BTA-8877813 https://reactome.org/PathwayBrowser/#/R-BTA-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Bos taurus 58189 R-BTA-8877998 https://reactome.org/PathwayBrowser/#/R-BTA-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Bos taurus 58189 R-BTA-8938815 https://reactome.org/PathwayBrowser/#/R-BTA-8938815 RNF152 polyubiquitinates RRAGA IEA Bos taurus 58189 R-BTA-8938829 https://reactome.org/PathwayBrowser/#/R-BTA-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 IEA Bos taurus 58189 R-BTA-8941613 https://reactome.org/PathwayBrowser/#/R-BTA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-8941618 https://reactome.org/PathwayBrowser/#/R-BTA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-8941623 https://reactome.org/PathwayBrowser/#/R-BTA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-8941628 https://reactome.org/PathwayBrowser/#/R-BTA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Bos taurus 58189 R-BTA-8944454 https://reactome.org/PathwayBrowser/#/R-BTA-8944454 mTORC1 phosphorylates MAF1 IEA Bos taurus 58189 R-BTA-8944457 https://reactome.org/PathwayBrowser/#/R-BTA-8944457 MAF1 translocates to the nucleus IEA Bos taurus 58189 R-BTA-8951498 https://reactome.org/PathwayBrowser/#/R-BTA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Bos taurus 58189 R-BTA-8951586 https://reactome.org/PathwayBrowser/#/R-BTA-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Bos taurus 58189 R-BTA-8952716 https://reactome.org/PathwayBrowser/#/R-BTA-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Bos taurus 58189 R-BTA-8952726 https://reactome.org/PathwayBrowser/#/R-BTA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Bos taurus 58189 R-BTA-8955724 https://reactome.org/PathwayBrowser/#/R-BTA-8955724 TTL ligates L-Tyr to the carboxy terminus of alpha-tubulin TAS Bos taurus 58189 R-BTA-8980691 https://reactome.org/PathwayBrowser/#/R-BTA-8980691 RHOA GEFs activate RHOA IEA Bos taurus 58189 R-BTA-8981353 https://reactome.org/PathwayBrowser/#/R-BTA-8981353 RASA1 stimulates RAS GTPase activity IEA Bos taurus 58189 R-BTA-8981637 https://reactome.org/PathwayBrowser/#/R-BTA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Bos taurus 58189 R-BTA-8982012 https://reactome.org/PathwayBrowser/#/R-BTA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Bos taurus 58189 R-BTA-8982018 https://reactome.org/PathwayBrowser/#/R-BTA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Bos taurus 58189 R-BTA-8982020 https://reactome.org/PathwayBrowser/#/R-BTA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Bos taurus 58189 R-BTA-8982021 https://reactome.org/PathwayBrowser/#/R-BTA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Bos taurus 58189 R-BTA-8982025 https://reactome.org/PathwayBrowser/#/R-BTA-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Bos taurus 58189 R-BTA-8982026 https://reactome.org/PathwayBrowser/#/R-BTA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Bos taurus 58189 R-BTA-8985594 https://reactome.org/PathwayBrowser/#/R-BTA-8985594 MYO9B inactivates RHOA IEA Bos taurus 58189 R-BTA-9012761 https://reactome.org/PathwayBrowser/#/R-BTA-9012761 The p75NTR:NgR:MDGI binds RHOA-GDI IEA Bos taurus 58189 R-BTA-9012835 https://reactome.org/PathwayBrowser/#/R-BTA-9012835 GDIs block activation of RHOA IEA Bos taurus 58189 R-BTA-9013108 https://reactome.org/PathwayBrowser/#/R-BTA-9013108 GDIs block activation of RHOC IEA Bos taurus 58189 R-BTA-9013109 https://reactome.org/PathwayBrowser/#/R-BTA-9013109 RHOC GEFs activate RHOC IEA Bos taurus 58189 R-BTA-9013111 https://reactome.org/PathwayBrowser/#/R-BTA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Bos taurus 58189 R-BTA-9013143 https://reactome.org/PathwayBrowser/#/R-BTA-9013143 RAC1 GEFs activate RAC1 IEA Bos taurus 58189 R-BTA-9013144 https://reactome.org/PathwayBrowser/#/R-BTA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Bos taurus 58189 R-BTA-9013147 https://reactome.org/PathwayBrowser/#/R-BTA-9013147 RAC1 GDIs block activation of RAC1 IEA Bos taurus 58189 R-BTA-9013158 https://reactome.org/PathwayBrowser/#/R-BTA-9013158 CDC42 GDIs block activation of CDC42 IEA Bos taurus 58189 R-BTA-9013159 https://reactome.org/PathwayBrowser/#/R-BTA-9013159 CDC42 GEFs activate CDC42 IEA Bos taurus 58189 R-BTA-9013161 https://reactome.org/PathwayBrowser/#/R-BTA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Bos taurus 58189 R-BTA-9013435 https://reactome.org/PathwayBrowser/#/R-BTA-9013435 RHOD auto-activates IEA Bos taurus 58189 R-BTA-9013437 https://reactome.org/PathwayBrowser/#/R-BTA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Bos taurus 58189 R-BTA-9014293 https://reactome.org/PathwayBrowser/#/R-BTA-9014293 RAC2 GDIs block activation of RAC2 IEA Bos taurus 58189 R-BTA-9014295 https://reactome.org/PathwayBrowser/#/R-BTA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Bos taurus 58189 R-BTA-9014296 https://reactome.org/PathwayBrowser/#/R-BTA-9014296 RAC2 GEFs activate RAC2 IEA Bos taurus 58189 R-BTA-9014433 https://reactome.org/PathwayBrowser/#/R-BTA-9014433 RHOG GEFs activate RHOG IEA Bos taurus 58189 R-BTA-9014434 https://reactome.org/PathwayBrowser/#/R-BTA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Bos taurus 58189 R-BTA-9014456 https://reactome.org/PathwayBrowser/#/R-BTA-9014456 GDIs block activation of RHOG IEA Bos taurus 58189 R-BTA-9017488 https://reactome.org/PathwayBrowser/#/R-BTA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Bos taurus 58189 R-BTA-9017491 https://reactome.org/PathwayBrowser/#/R-BTA-9017491 RHOJ GEFs activate RHOJ IEA Bos taurus 58189 R-BTA-9018745 https://reactome.org/PathwayBrowser/#/R-BTA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Bos taurus 58189 R-BTA-9018747 https://reactome.org/PathwayBrowser/#/R-BTA-9018747 RHOQ GEFs activate RHOQ IEA Bos taurus 58189 R-BTA-9018768 https://reactome.org/PathwayBrowser/#/R-BTA-9018768 RHOU auto-activates IEA Bos taurus 58189 R-BTA-9018798 https://reactome.org/PathwayBrowser/#/R-BTA-9018798 RHOV binds GTP IEA Bos taurus 58189 R-BTA-9018804 https://reactome.org/PathwayBrowser/#/R-BTA-9018804 RAC3 GEFs activate RAC3 IEA Bos taurus 58189 R-BTA-9018806 https://reactome.org/PathwayBrowser/#/R-BTA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Bos taurus 58189 R-BTA-9018807 https://reactome.org/PathwayBrowser/#/R-BTA-9018807 RAC3 GDIs block activation of RAC3 IEA Bos taurus 58189 R-BTA-9018814 https://reactome.org/PathwayBrowser/#/R-BTA-9018814 RHOT1 hydrolyzes GTP IEA Bos taurus 58189 R-BTA-9018826 https://reactome.org/PathwayBrowser/#/R-BTA-9018826 RHOT2 hydrolyzes GTP IEA Bos taurus 58189 R-BTA-9032798 https://reactome.org/PathwayBrowser/#/R-BTA-9032798 DOCK3 activates RAC1 IEA Bos taurus 58189 R-BTA-9033949 https://reactome.org/PathwayBrowser/#/R-BTA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Bos taurus 58189 R-BTA-9036987 https://reactome.org/PathwayBrowser/#/R-BTA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Bos taurus 58189 R-BTA-927789 https://reactome.org/PathwayBrowser/#/R-BTA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Bos taurus 58189 R-BTA-927813 https://reactome.org/PathwayBrowser/#/R-BTA-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Bos taurus 58189 R-BTA-927832 https://reactome.org/PathwayBrowser/#/R-BTA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Bos taurus 58189 R-BTA-927836 https://reactome.org/PathwayBrowser/#/R-BTA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Bos taurus 58189 R-BTA-927889 https://reactome.org/PathwayBrowser/#/R-BTA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Bos taurus 58189 R-BTA-939265 https://reactome.org/PathwayBrowser/#/R-BTA-939265 Activation of Rap1 by membrane-associated GEFs IEA Bos taurus 58189 R-BTA-9603982 https://reactome.org/PathwayBrowser/#/R-BTA-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Bos taurus 58189 R-BTA-9603983 https://reactome.org/PathwayBrowser/#/R-BTA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Bos taurus 58189 R-BTA-9603984 https://reactome.org/PathwayBrowser/#/R-BTA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Bos taurus 58189 R-BTA-9603986 https://reactome.org/PathwayBrowser/#/R-BTA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Bos taurus 58189 R-BTA-9605609 https://reactome.org/PathwayBrowser/#/R-BTA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Bos taurus 58189 R-BTA-9605644 https://reactome.org/PathwayBrowser/#/R-BTA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Bos taurus 58189 R-BTA-9605682 https://reactome.org/PathwayBrowser/#/R-BTA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Bos taurus 58189 R-BTA-9607304 https://reactome.org/PathwayBrowser/#/R-BTA-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Bos taurus 58189 R-BTA-9624845 https://reactome.org/PathwayBrowser/#/R-BTA-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Bos taurus 58189 R-BTA-9624893 https://reactome.org/PathwayBrowser/#/R-BTA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Bos taurus 58189 R-BTA-9632906 https://reactome.org/PathwayBrowser/#/R-BTA-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Bos taurus 58189 R-BTA-9632918 https://reactome.org/PathwayBrowser/#/R-BTA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Bos taurus 58189 R-BTA-9639286 https://reactome.org/PathwayBrowser/#/R-BTA-9639286 RRAGC,D exchanges GTP for GDP IEA Bos taurus 58189 R-BTA-9640167 https://reactome.org/PathwayBrowser/#/R-BTA-9640167 RRAGA,B exchanges GDP for GTP IEA Bos taurus 58189 R-BTA-9640168 https://reactome.org/PathwayBrowser/#/R-BTA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Bos taurus 58189 R-BTA-9640175 https://reactome.org/PathwayBrowser/#/R-BTA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Bos taurus 58189 R-BTA-9640195 https://reactome.org/PathwayBrowser/#/R-BTA-9640195 RRAGA,B hydrolyzes GTP IEA Bos taurus 58189 R-BTA-9645598 https://reactome.org/PathwayBrowser/#/R-BTA-9645598 RRAGC,D hydrolyzes GTP IEA Bos taurus 58189 R-BTA-9645608 https://reactome.org/PathwayBrowser/#/R-BTA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Bos taurus 58189 R-BTA-9646468 https://reactome.org/PathwayBrowser/#/R-BTA-9646468 mTORC1 binds RHEB:GTP IEA Bos taurus 58189 R-BTA-9646679 https://reactome.org/PathwayBrowser/#/R-BTA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Bos taurus 58189 R-BTA-9646685 https://reactome.org/PathwayBrowser/#/R-BTA-9646685 Aggresome dissociates from dynein and microtubule IEA Bos taurus 58189 R-BTA-9648017 https://reactome.org/PathwayBrowser/#/R-BTA-9648017 EML4 binds to microtubules IEA Bos taurus 58189 R-BTA-9648114 https://reactome.org/PathwayBrowser/#/R-BTA-9648114 EML4 recruits NUDC to mitotic spindle IEA Bos taurus 58189 R-BTA-9649733 https://reactome.org/PathwayBrowser/#/R-BTA-9649733 mature p21 RAS binds GDP IEA Bos taurus 58189 R-BTA-9649735 https://reactome.org/PathwayBrowser/#/R-BTA-9649735 Intrinsic nucleotide exchange on RAS IEA Bos taurus 58189 R-BTA-9649736 https://reactome.org/PathwayBrowser/#/R-BTA-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Bos taurus 58189 R-BTA-9668419 https://reactome.org/PathwayBrowser/#/R-BTA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Bos taurus 58189 R-BTA-9693111 https://reactome.org/PathwayBrowser/#/R-BTA-9693111 RHOF auto-activates IEA Bos taurus 58189 R-BTA-9693282 https://reactome.org/PathwayBrowser/#/R-BTA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Bos taurus 58189 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 58189 R-BTA-9717206 https://reactome.org/PathwayBrowser/#/R-BTA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Bos taurus 58189 R-BTA-9726862 https://reactome.org/PathwayBrowser/#/R-BTA-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Bos taurus 58189 R-BTA-9728664 https://reactome.org/PathwayBrowser/#/R-BTA-9728664 GLP1R binds GLP1R agonists IEA Bos taurus 58189 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 58189 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 58189 R-BTA-9751201 https://reactome.org/PathwayBrowser/#/R-BTA-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Bos taurus 58189 R-BTA-983259 https://reactome.org/PathwayBrowser/#/R-BTA-983259 Kinesins move along microtubules consuming ATP IEA Bos taurus 58189 R-BTA-983266 https://reactome.org/PathwayBrowser/#/R-BTA-983266 Kinesins bind microtubules IEA Bos taurus 58189 R-BTA-983422 https://reactome.org/PathwayBrowser/#/R-BTA-983422 Disassembly of COPII coated vesicle IEA Bos taurus 58189 R-BTA-9846332 https://reactome.org/PathwayBrowser/#/R-BTA-9846332 FUT1,2 transfer fucose to gangliosides IEA Bos taurus 58189 R-CEL-1028788 https://reactome.org/PathwayBrowser/#/R-CEL-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Caenorhabditis elegans 58189 R-CEL-110133 https://reactome.org/PathwayBrowser/#/R-CEL-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Caenorhabditis elegans 58189 R-CEL-111524 https://reactome.org/PathwayBrowser/#/R-CEL-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Caenorhabditis elegans 58189 R-CEL-112037 https://reactome.org/PathwayBrowser/#/R-CEL-112037 Inactivation of PLC beta IEA Caenorhabditis elegans 58189 R-CEL-114544 https://reactome.org/PathwayBrowser/#/R-CEL-114544 p115-RhoGEF activation of RHOA IEA Caenorhabditis elegans 58189 R-CEL-114552 https://reactome.org/PathwayBrowser/#/R-CEL-114552 Thrombin-activated PARs activate G12/13 IEA Caenorhabditis elegans 58189 R-CEL-114558 https://reactome.org/PathwayBrowser/#/R-CEL-114558 Thrombin-activated PARs activate Gq IEA Caenorhabditis elegans 58189 R-CEL-1168636 https://reactome.org/PathwayBrowser/#/R-CEL-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Caenorhabditis elegans 58189 R-CEL-1306972 https://reactome.org/PathwayBrowser/#/R-CEL-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Caenorhabditis elegans 58189 R-CEL-1433415 https://reactome.org/PathwayBrowser/#/R-CEL-1433415 Activation of RAC1 IEA Caenorhabditis elegans 58189 R-CEL-1433471 https://reactome.org/PathwayBrowser/#/R-CEL-1433471 Activation of RAS by p-KIT bound SOS1 IEA Caenorhabditis elegans 58189 R-CEL-165195 https://reactome.org/PathwayBrowser/#/R-CEL-165195 GTP loading by Rheb IEA Caenorhabditis elegans 58189 R-CEL-165680 https://reactome.org/PathwayBrowser/#/R-CEL-165680 Formation of active mTORC1 complex IEA Caenorhabditis elegans 58189 R-CEL-165718 https://reactome.org/PathwayBrowser/#/R-CEL-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Caenorhabditis elegans 58189 R-CEL-167415 https://reactome.org/PathwayBrowser/#/R-CEL-167415 G-protein alpha subunit is inactivated IEA Caenorhabditis elegans 58189 R-CEL-167419 https://reactome.org/PathwayBrowser/#/R-CEL-167419 The receptor:G-protein complex releases GDP IEA Caenorhabditis elegans 58189 R-CEL-167433 https://reactome.org/PathwayBrowser/#/R-CEL-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Caenorhabditis elegans 58189 R-CEL-170026 https://reactome.org/PathwayBrowser/#/R-CEL-170026 Protons are translocated from the intermembrane space to the matrix IEA Caenorhabditis elegans 58189 R-CEL-170666 https://reactome.org/PathwayBrowser/#/R-CEL-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Caenorhabditis elegans 58189 R-CEL-170674 https://reactome.org/PathwayBrowser/#/R-CEL-170674 Dissociation of the Gi alpha:G olf complex IEA Caenorhabditis elegans 58189 R-CEL-170677 https://reactome.org/PathwayBrowser/#/R-CEL-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Caenorhabditis elegans 58189 R-CEL-170685 https://reactome.org/PathwayBrowser/#/R-CEL-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Caenorhabditis elegans 58189 R-CEL-170686 https://reactome.org/PathwayBrowser/#/R-CEL-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Caenorhabditis elegans 58189 R-CEL-177938 https://reactome.org/PathwayBrowser/#/R-CEL-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Caenorhabditis elegans 58189 R-CEL-177945 https://reactome.org/PathwayBrowser/#/R-CEL-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Caenorhabditis elegans 58189 R-CEL-186834 https://reactome.org/PathwayBrowser/#/R-CEL-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Caenorhabditis elegans 58189 R-CEL-194518 https://reactome.org/PathwayBrowser/#/R-CEL-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Caenorhabditis elegans 58189 R-CEL-203977 https://reactome.org/PathwayBrowser/#/R-CEL-203977 SAR1 Activation And Membrane Binding IEA Caenorhabditis elegans 58189 R-CEL-205039 https://reactome.org/PathwayBrowser/#/R-CEL-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Caenorhabditis elegans 58189 R-CEL-2179407 https://reactome.org/PathwayBrowser/#/R-CEL-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Caenorhabditis elegans 58189 R-CEL-350769 https://reactome.org/PathwayBrowser/#/R-CEL-350769 trans-Golgi Network Coat Activation IEA Caenorhabditis elegans 58189 R-CEL-354173 https://reactome.org/PathwayBrowser/#/R-CEL-354173 Activation of Rap1 by cytosolic GEFs IEA Caenorhabditis elegans 58189 R-CEL-372819 https://reactome.org/PathwayBrowser/#/R-CEL-372819 PCK2 phosphorylates OA to yield PEP IEA Caenorhabditis elegans 58189 R-CEL-377186 https://reactome.org/PathwayBrowser/#/R-CEL-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Caenorhabditis elegans 58189 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 58189 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 58189 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 58189 R-CEL-380979 https://reactome.org/PathwayBrowser/#/R-CEL-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Caenorhabditis elegans 58189 R-CEL-381727 https://reactome.org/PathwayBrowser/#/R-CEL-381727 RAP1A exchanges GDP for GTP IEA Caenorhabditis elegans 58189 R-CEL-392054 https://reactome.org/PathwayBrowser/#/R-CEL-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Caenorhabditis elegans 58189 R-CEL-392195 https://reactome.org/PathwayBrowser/#/R-CEL-392195 Gi activation by P2Y purinoceptor 12 IEA Caenorhabditis elegans 58189 R-CEL-392513 https://reactome.org/PathwayBrowser/#/R-CEL-392513 Rap1 signal termination by Rap1GAPs IEA Caenorhabditis elegans 58189 R-CEL-3928592 https://reactome.org/PathwayBrowser/#/R-CEL-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Caenorhabditis elegans 58189 R-CEL-3928628 https://reactome.org/PathwayBrowser/#/R-CEL-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 58189 R-CEL-3928642 https://reactome.org/PathwayBrowser/#/R-CEL-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 58189 R-CEL-3928651 https://reactome.org/PathwayBrowser/#/R-CEL-3928651 NGEF exchanges GTP for GDP on RHOA IEA Caenorhabditis elegans 58189 R-CEL-3965444 https://reactome.org/PathwayBrowser/#/R-CEL-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-400092 https://reactome.org/PathwayBrowser/#/R-CEL-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Caenorhabditis elegans 58189 R-CEL-4093336 https://reactome.org/PathwayBrowser/#/R-CEL-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 58189 R-CEL-4093339 https://reactome.org/PathwayBrowser/#/R-CEL-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Caenorhabditis elegans 58189 R-CEL-416559 https://reactome.org/PathwayBrowser/#/R-CEL-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Caenorhabditis elegans 58189 R-CEL-416588 https://reactome.org/PathwayBrowser/#/R-CEL-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Caenorhabditis elegans 58189 R-CEL-418850 https://reactome.org/PathwayBrowser/#/R-CEL-418850 Activation of Cdc42 IEA Caenorhabditis elegans 58189 R-CEL-418856 https://reactome.org/PathwayBrowser/#/R-CEL-418856 Activation of Rac1 IEA Caenorhabditis elegans 58189 R-CEL-419166 https://reactome.org/PathwayBrowser/#/R-CEL-419166 GEFs activate RhoA,B,C IEA Caenorhabditis elegans 58189 R-CEL-420883 https://reactome.org/PathwayBrowser/#/R-CEL-420883 Opsins act as GEFs for G alpha-t IEA Caenorhabditis elegans 58189 R-CEL-421831 https://reactome.org/PathwayBrowser/#/R-CEL-421831 trans-Golgi Network Coat Assembly IEA Caenorhabditis elegans 58189 R-CEL-421835 https://reactome.org/PathwayBrowser/#/R-CEL-421835 trans-Golgi Network Vesicle Scission IEA Caenorhabditis elegans 58189 R-CEL-428750 https://reactome.org/PathwayBrowser/#/R-CEL-428750 Gq activation by TP receptor IEA Caenorhabditis elegans 58189 R-CEL-428917 https://reactome.org/PathwayBrowser/#/R-CEL-428917 G13 activation by TP receptor IEA Caenorhabditis elegans 58189 R-CEL-432706 https://reactome.org/PathwayBrowser/#/R-CEL-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Caenorhabditis elegans 58189 R-CEL-432707 https://reactome.org/PathwayBrowser/#/R-CEL-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Caenorhabditis elegans 58189 R-CEL-442273 https://reactome.org/PathwayBrowser/#/R-CEL-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Caenorhabditis elegans 58189 R-CEL-442291 https://reactome.org/PathwayBrowser/#/R-CEL-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Caenorhabditis elegans 58189 R-CEL-442314 https://reactome.org/PathwayBrowser/#/R-CEL-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Caenorhabditis elegans 58189 R-CEL-445064 https://reactome.org/PathwayBrowser/#/R-CEL-445064 Activation of Rac1 by VAV2 IEA Caenorhabditis elegans 58189 R-CEL-446208 https://reactome.org/PathwayBrowser/#/R-CEL-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Caenorhabditis elegans 58189 R-CEL-446218 https://reactome.org/PathwayBrowser/#/R-CEL-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Caenorhabditis elegans 58189 R-CEL-447074 https://reactome.org/PathwayBrowser/#/R-CEL-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Caenorhabditis elegans 58189 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 58189 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 58189 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 58189 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 58189 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 58189 R-CEL-5218850 https://reactome.org/PathwayBrowser/#/R-CEL-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 58189 R-CEL-5419271 https://reactome.org/PathwayBrowser/#/R-CEL-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Caenorhabditis elegans 58189 R-CEL-5419273 https://reactome.org/PathwayBrowser/#/R-CEL-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Caenorhabditis elegans 58189 R-CEL-555065 https://reactome.org/PathwayBrowser/#/R-CEL-555065 Formation of clathrin coated vesicle IEA Caenorhabditis elegans 58189 R-CEL-5623519 https://reactome.org/PathwayBrowser/#/R-CEL-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Caenorhabditis elegans 58189 R-CEL-5623521 https://reactome.org/PathwayBrowser/#/R-CEL-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Caenorhabditis elegans 58189 R-CEL-5625416 https://reactome.org/PathwayBrowser/#/R-CEL-5625416 Anterograde IFT IEA Caenorhabditis elegans 58189 R-CEL-5625426 https://reactome.org/PathwayBrowser/#/R-CEL-5625426 Retrograde IFT IEA Caenorhabditis elegans 58189 R-CEL-5653957 https://reactome.org/PathwayBrowser/#/R-CEL-5653957 Rag dimer formation IEA Caenorhabditis elegans 58189 R-CEL-5653968 https://reactome.org/PathwayBrowser/#/R-CEL-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Caenorhabditis elegans 58189 R-CEL-5654392 https://reactome.org/PathwayBrowser/#/R-CEL-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-5654402 https://reactome.org/PathwayBrowser/#/R-CEL-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-5654413 https://reactome.org/PathwayBrowser/#/R-CEL-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-5654426 https://reactome.org/PathwayBrowser/#/R-CEL-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-5654600 https://reactome.org/PathwayBrowser/#/R-CEL-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-5654618 https://reactome.org/PathwayBrowser/#/R-CEL-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-5654647 https://reactome.org/PathwayBrowser/#/R-CEL-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-5654663 https://reactome.org/PathwayBrowser/#/R-CEL-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-5672010 https://reactome.org/PathwayBrowser/#/R-CEL-5672010 Active MTORC1 phosphorylates ULK1 IEA Caenorhabditis elegans 58189 R-CEL-5672017 https://reactome.org/PathwayBrowser/#/R-CEL-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Caenorhabditis elegans 58189 R-CEL-5672817 https://reactome.org/PathwayBrowser/#/R-CEL-5672817 Active MTORC1 binds the ULK1 complex IEA Caenorhabditis elegans 58189 R-CEL-5672824 https://reactome.org/PathwayBrowser/#/R-CEL-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Caenorhabditis elegans 58189 R-CEL-5672828 https://reactome.org/PathwayBrowser/#/R-CEL-5672828 mTORC1 phosphorylates AKT1S1 IEA Caenorhabditis elegans 58189 R-CEL-5672965 https://reactome.org/PathwayBrowser/#/R-CEL-5672965 RAS GEFs promote RAS nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-5673768 https://reactome.org/PathwayBrowser/#/R-CEL-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Caenorhabditis elegans 58189 R-CEL-5675790 https://reactome.org/PathwayBrowser/#/R-CEL-5675790 MTORC1 dissociates from ULK complex IEA Caenorhabditis elegans 58189 R-CEL-5693925 https://reactome.org/PathwayBrowser/#/R-CEL-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Caenorhabditis elegans 58189 R-CEL-5694409 https://reactome.org/PathwayBrowser/#/R-CEL-5694409 Nucleotide exchange on RAB1 IEA Caenorhabditis elegans 58189 R-CEL-5694439 https://reactome.org/PathwayBrowser/#/R-CEL-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Caenorhabditis elegans 58189 R-CEL-5694527 https://reactome.org/PathwayBrowser/#/R-CEL-5694527 Loss of SAR1B GTPase IEA Caenorhabditis elegans 58189 R-CEL-6807868 https://reactome.org/PathwayBrowser/#/R-CEL-6807868 GBF1 stimulates ARF nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-6809003 https://reactome.org/PathwayBrowser/#/R-CEL-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Caenorhabditis elegans 58189 R-CEL-6811426 https://reactome.org/PathwayBrowser/#/R-CEL-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Caenorhabditis elegans 58189 R-CEL-6811427 https://reactome.org/PathwayBrowser/#/R-CEL-6811427 COPI vesicle uncoating at the ER IEA Caenorhabditis elegans 58189 R-CEL-6811428 https://reactome.org/PathwayBrowser/#/R-CEL-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Caenorhabditis elegans 58189 R-CEL-6811429 https://reactome.org/PathwayBrowser/#/R-CEL-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Caenorhabditis elegans 58189 R-CEL-6814833 https://reactome.org/PathwayBrowser/#/R-CEL-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Caenorhabditis elegans 58189 R-CEL-70241 https://reactome.org/PathwayBrowser/#/R-CEL-70241 PCK1 phosphorylates OA to yield PEP IEA Caenorhabditis elegans 58189 R-CEL-71775 https://reactome.org/PathwayBrowser/#/R-CEL-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Caenorhabditis elegans 58189 R-CEL-72670 https://reactome.org/PathwayBrowser/#/R-CEL-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Caenorhabditis elegans 58189 R-CEL-72671 https://reactome.org/PathwayBrowser/#/R-CEL-72671 eIF5B:GTP is hydrolyzed and released IEA Caenorhabditis elegans 58189 R-CEL-72722 https://reactome.org/PathwayBrowser/#/R-CEL-72722 eIF2 activation IEA Caenorhabditis elegans 58189 R-CEL-73788 https://reactome.org/PathwayBrowser/#/R-CEL-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Caenorhabditis elegans 58189 R-CEL-749453 https://reactome.org/PathwayBrowser/#/R-CEL-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Caenorhabditis elegans 58189 R-CEL-751029 https://reactome.org/PathwayBrowser/#/R-CEL-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Caenorhabditis elegans 58189 R-CEL-8847534 https://reactome.org/PathwayBrowser/#/R-CEL-8847534 RAB43 hydrolyses GTP IEA Caenorhabditis elegans 58189 R-CEL-8848618 https://reactome.org/PathwayBrowser/#/R-CEL-8848618 Activation of RAC1 by the PXN:CRK complex IEA Caenorhabditis elegans 58189 R-CEL-8849082 https://reactome.org/PathwayBrowser/#/R-CEL-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-8849350 https://reactome.org/PathwayBrowser/#/R-CEL-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Caenorhabditis elegans 58189 R-CEL-8849353 https://reactome.org/PathwayBrowser/#/R-CEL-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Caenorhabditis elegans 58189 R-CEL-8850040 https://reactome.org/PathwayBrowser/#/R-CEL-8850040 RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER IEA Caenorhabditis elegans 58189 R-CEL-8850041 https://reactome.org/PathwayBrowser/#/R-CEL-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Caenorhabditis elegans 58189 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58189 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 58189 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58189 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58189 R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 58189 R-CEL-8851827 https://reactome.org/PathwayBrowser/#/R-CEL-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Caenorhabditis elegans 58189 R-CEL-8851877 https://reactome.org/PathwayBrowser/#/R-CEL-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Caenorhabditis elegans 58189 R-CEL-8851899 https://reactome.org/PathwayBrowser/#/R-CEL-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Caenorhabditis elegans 58189 R-CEL-8854173 https://reactome.org/PathwayBrowser/#/R-CEL-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Caenorhabditis elegans 58189 R-CEL-8854255 https://reactome.org/PathwayBrowser/#/R-CEL-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 58189 R-CEL-8854612 https://reactome.org/PathwayBrowser/#/R-CEL-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Caenorhabditis elegans 58189 R-CEL-8868658 https://reactome.org/PathwayBrowser/#/R-CEL-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Caenorhabditis elegans 58189 R-CEL-8868659 https://reactome.org/PathwayBrowser/#/R-CEL-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Caenorhabditis elegans 58189 R-CEL-8868660 https://reactome.org/PathwayBrowser/#/R-CEL-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Caenorhabditis elegans 58189 R-CEL-8868661 https://reactome.org/PathwayBrowser/#/R-CEL-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Caenorhabditis elegans 58189 R-CEL-8870466 https://reactome.org/PathwayBrowser/#/R-CEL-8870466 RGGT:CHM binds RABs IEA Caenorhabditis elegans 58189 R-CEL-8870469 https://reactome.org/PathwayBrowser/#/R-CEL-8870469 RGGT geranylgeranylates RAB proteins IEA Caenorhabditis elegans 58189 R-CEL-8871194 https://reactome.org/PathwayBrowser/#/R-CEL-8871194 RAB5 and GAPVD1 bind AP-2 IEA Caenorhabditis elegans 58189 R-CEL-8875318 https://reactome.org/PathwayBrowser/#/R-CEL-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Caenorhabditis elegans 58189 R-CEL-8875320 https://reactome.org/PathwayBrowser/#/R-CEL-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Caenorhabditis elegans 58189 R-CEL-8875568 https://reactome.org/PathwayBrowser/#/R-CEL-8875568 RAPGEF1 activates RAP1 IEA Caenorhabditis elegans 58189 R-CEL-8875591 https://reactome.org/PathwayBrowser/#/R-CEL-8875591 DOCK7 activates RAC1 IEA Caenorhabditis elegans 58189 R-CEL-8876188 https://reactome.org/PathwayBrowser/#/R-CEL-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Caenorhabditis elegans 58189 R-CEL-8876190 https://reactome.org/PathwayBrowser/#/R-CEL-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Caenorhabditis elegans 58189 R-CEL-8876193 https://reactome.org/PathwayBrowser/#/R-CEL-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Caenorhabditis elegans 58189 R-CEL-8876615 https://reactome.org/PathwayBrowser/#/R-CEL-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Caenorhabditis elegans 58189 R-CEL-8876616 https://reactome.org/PathwayBrowser/#/R-CEL-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Caenorhabditis elegans 58189 R-CEL-8876837 https://reactome.org/PathwayBrowser/#/R-CEL-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Caenorhabditis elegans 58189 R-CEL-8877308 https://reactome.org/PathwayBrowser/#/R-CEL-8877308 MADD exchanges GTP for GDP on RAB27 IEA Caenorhabditis elegans 58189 R-CEL-8877451 https://reactome.org/PathwayBrowser/#/R-CEL-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Caenorhabditis elegans 58189 R-CEL-8877475 https://reactome.org/PathwayBrowser/#/R-CEL-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Caenorhabditis elegans 58189 R-CEL-8877612 https://reactome.org/PathwayBrowser/#/R-CEL-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Caenorhabditis elegans 58189 R-CEL-8877813 https://reactome.org/PathwayBrowser/#/R-CEL-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Caenorhabditis elegans 58189 R-CEL-8877998 https://reactome.org/PathwayBrowser/#/R-CEL-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Caenorhabditis elegans 58189 R-CEL-8944454 https://reactome.org/PathwayBrowser/#/R-CEL-8944454 mTORC1 phosphorylates MAF1 IEA Caenorhabditis elegans 58189 R-CEL-8944457 https://reactome.org/PathwayBrowser/#/R-CEL-8944457 MAF1 translocates to the nucleus IEA Caenorhabditis elegans 58189 R-CEL-8951586 https://reactome.org/PathwayBrowser/#/R-CEL-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Caenorhabditis elegans 58189 R-CEL-8952726 https://reactome.org/PathwayBrowser/#/R-CEL-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Caenorhabditis elegans 58189 R-CEL-8980691 https://reactome.org/PathwayBrowser/#/R-CEL-8980691 RHOA GEFs activate RHOA IEA Caenorhabditis elegans 58189 R-CEL-8981637 https://reactome.org/PathwayBrowser/#/R-CEL-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-8982012 https://reactome.org/PathwayBrowser/#/R-CEL-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Caenorhabditis elegans 58189 R-CEL-8982018 https://reactome.org/PathwayBrowser/#/R-CEL-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Caenorhabditis elegans 58189 R-CEL-8982020 https://reactome.org/PathwayBrowser/#/R-CEL-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Caenorhabditis elegans 58189 R-CEL-8982021 https://reactome.org/PathwayBrowser/#/R-CEL-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Caenorhabditis elegans 58189 R-CEL-8982025 https://reactome.org/PathwayBrowser/#/R-CEL-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Caenorhabditis elegans 58189 R-CEL-8982026 https://reactome.org/PathwayBrowser/#/R-CEL-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Caenorhabditis elegans 58189 R-CEL-8985594 https://reactome.org/PathwayBrowser/#/R-CEL-8985594 MYO9B inactivates RHOA IEA Caenorhabditis elegans 58189 R-CEL-9012835 https://reactome.org/PathwayBrowser/#/R-CEL-9012835 GDIs block activation of RHOA IEA Caenorhabditis elegans 58189 R-CEL-9013021 https://reactome.org/PathwayBrowser/#/R-CEL-9013021 GDIs block activation of RHOB IEA Caenorhabditis elegans 58189 R-CEL-9013022 https://reactome.org/PathwayBrowser/#/R-CEL-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-9013023 https://reactome.org/PathwayBrowser/#/R-CEL-9013023 RHOB GEFs activate RHOB IEA Caenorhabditis elegans 58189 R-CEL-9013143 https://reactome.org/PathwayBrowser/#/R-CEL-9013143 RAC1 GEFs activate RAC1 IEA Caenorhabditis elegans 58189 R-CEL-9013144 https://reactome.org/PathwayBrowser/#/R-CEL-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-9013147 https://reactome.org/PathwayBrowser/#/R-CEL-9013147 RAC1 GDIs block activation of RAC1 IEA Caenorhabditis elegans 58189 R-CEL-9013158 https://reactome.org/PathwayBrowser/#/R-CEL-9013158 CDC42 GDIs block activation of CDC42 IEA Caenorhabditis elegans 58189 R-CEL-9013159 https://reactome.org/PathwayBrowser/#/R-CEL-9013159 CDC42 GEFs activate CDC42 IEA Caenorhabditis elegans 58189 R-CEL-9013161 https://reactome.org/PathwayBrowser/#/R-CEL-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-9013435 https://reactome.org/PathwayBrowser/#/R-CEL-9013435 RHOD auto-activates IEA Caenorhabditis elegans 58189 R-CEL-9013437 https://reactome.org/PathwayBrowser/#/R-CEL-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-9014293 https://reactome.org/PathwayBrowser/#/R-CEL-9014293 RAC2 GDIs block activation of RAC2 IEA Caenorhabditis elegans 58189 R-CEL-9014295 https://reactome.org/PathwayBrowser/#/R-CEL-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-9014296 https://reactome.org/PathwayBrowser/#/R-CEL-9014296 RAC2 GEFs activate RAC2 IEA Caenorhabditis elegans 58189 R-CEL-9014433 https://reactome.org/PathwayBrowser/#/R-CEL-9014433 RHOG GEFs activate RHOG IEA Caenorhabditis elegans 58189 R-CEL-9014434 https://reactome.org/PathwayBrowser/#/R-CEL-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-9014456 https://reactome.org/PathwayBrowser/#/R-CEL-9014456 GDIs block activation of RHOG IEA Caenorhabditis elegans 58189 R-CEL-9017488 https://reactome.org/PathwayBrowser/#/R-CEL-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-9017491 https://reactome.org/PathwayBrowser/#/R-CEL-9017491 RHOJ GEFs activate RHOJ IEA Caenorhabditis elegans 58189 R-CEL-9018745 https://reactome.org/PathwayBrowser/#/R-CEL-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-9018747 https://reactome.org/PathwayBrowser/#/R-CEL-9018747 RHOQ GEFs activate RHOQ IEA Caenorhabditis elegans 58189 R-CEL-9018768 https://reactome.org/PathwayBrowser/#/R-CEL-9018768 RHOU auto-activates IEA Caenorhabditis elegans 58189 R-CEL-9018798 https://reactome.org/PathwayBrowser/#/R-CEL-9018798 RHOV binds GTP IEA Caenorhabditis elegans 58189 R-CEL-9018804 https://reactome.org/PathwayBrowser/#/R-CEL-9018804 RAC3 GEFs activate RAC3 IEA Caenorhabditis elegans 58189 R-CEL-9018806 https://reactome.org/PathwayBrowser/#/R-CEL-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-9018807 https://reactome.org/PathwayBrowser/#/R-CEL-9018807 RAC3 GDIs block activation of RAC3 IEA Caenorhabditis elegans 58189 R-CEL-9018814 https://reactome.org/PathwayBrowser/#/R-CEL-9018814 RHOT1 hydrolyzes GTP IEA Caenorhabditis elegans 58189 R-CEL-9018826 https://reactome.org/PathwayBrowser/#/R-CEL-9018826 RHOT2 hydrolyzes GTP IEA Caenorhabditis elegans 58189 R-CEL-9033949 https://reactome.org/PathwayBrowser/#/R-CEL-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Caenorhabditis elegans 58189 R-CEL-9036987 https://reactome.org/PathwayBrowser/#/R-CEL-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Caenorhabditis elegans 58189 R-CEL-927789 https://reactome.org/PathwayBrowser/#/R-CEL-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Caenorhabditis elegans 58189 R-CEL-927832 https://reactome.org/PathwayBrowser/#/R-CEL-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Caenorhabditis elegans 58189 R-CEL-927836 https://reactome.org/PathwayBrowser/#/R-CEL-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Caenorhabditis elegans 58189 R-CEL-927889 https://reactome.org/PathwayBrowser/#/R-CEL-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Caenorhabditis elegans 58189 R-CEL-939265 https://reactome.org/PathwayBrowser/#/R-CEL-939265 Activation of Rap1 by membrane-associated GEFs IEA Caenorhabditis elegans 58189 R-CEL-9603982 https://reactome.org/PathwayBrowser/#/R-CEL-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Caenorhabditis elegans 58189 R-CEL-9603983 https://reactome.org/PathwayBrowser/#/R-CEL-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Caenorhabditis elegans 58189 R-CEL-9603984 https://reactome.org/PathwayBrowser/#/R-CEL-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Caenorhabditis elegans 58189 R-CEL-9603986 https://reactome.org/PathwayBrowser/#/R-CEL-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Caenorhabditis elegans 58189 R-CEL-9605609 https://reactome.org/PathwayBrowser/#/R-CEL-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Caenorhabditis elegans 58189 R-CEL-9605644 https://reactome.org/PathwayBrowser/#/R-CEL-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Caenorhabditis elegans 58189 R-CEL-9605682 https://reactome.org/PathwayBrowser/#/R-CEL-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Caenorhabditis elegans 58189 R-CEL-9607304 https://reactome.org/PathwayBrowser/#/R-CEL-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Caenorhabditis elegans 58189 R-CEL-9624845 https://reactome.org/PathwayBrowser/#/R-CEL-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Caenorhabditis elegans 58189 R-CEL-9624893 https://reactome.org/PathwayBrowser/#/R-CEL-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Caenorhabditis elegans 58189 R-CEL-9632906 https://reactome.org/PathwayBrowser/#/R-CEL-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Caenorhabditis elegans 58189 R-CEL-9632918 https://reactome.org/PathwayBrowser/#/R-CEL-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Caenorhabditis elegans 58189 R-CEL-9639286 https://reactome.org/PathwayBrowser/#/R-CEL-9639286 RRAGC,D exchanges GTP for GDP IEA Caenorhabditis elegans 58189 R-CEL-9640167 https://reactome.org/PathwayBrowser/#/R-CEL-9640167 RRAGA,B exchanges GDP for GTP IEA Caenorhabditis elegans 58189 R-CEL-9640168 https://reactome.org/PathwayBrowser/#/R-CEL-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Caenorhabditis elegans 58189 R-CEL-9640175 https://reactome.org/PathwayBrowser/#/R-CEL-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Caenorhabditis elegans 58189 R-CEL-9640195 https://reactome.org/PathwayBrowser/#/R-CEL-9640195 RRAGA,B hydrolyzes GTP IEA Caenorhabditis elegans 58189 R-CEL-9645598 https://reactome.org/PathwayBrowser/#/R-CEL-9645598 RRAGC,D hydrolyzes GTP IEA Caenorhabditis elegans 58189 R-CEL-9645608 https://reactome.org/PathwayBrowser/#/R-CEL-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Caenorhabditis elegans 58189 R-CEL-9646468 https://reactome.org/PathwayBrowser/#/R-CEL-9646468 mTORC1 binds RHEB:GTP IEA Caenorhabditis elegans 58189 R-CEL-9649733 https://reactome.org/PathwayBrowser/#/R-CEL-9649733 mature p21 RAS binds GDP IEA Caenorhabditis elegans 58189 R-CEL-9649735 https://reactome.org/PathwayBrowser/#/R-CEL-9649735 Intrinsic nucleotide exchange on RAS IEA Caenorhabditis elegans 58189 R-CEL-9649736 https://reactome.org/PathwayBrowser/#/R-CEL-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Caenorhabditis elegans 58189 R-CEL-9693111 https://reactome.org/PathwayBrowser/#/R-CEL-9693111 RHOF auto-activates IEA Caenorhabditis elegans 58189 R-CEL-9693282 https://reactome.org/PathwayBrowser/#/R-CEL-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Caenorhabditis elegans 58189 R-CEL-9726862 https://reactome.org/PathwayBrowser/#/R-CEL-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Caenorhabditis elegans 58189 R-CEL-9751201 https://reactome.org/PathwayBrowser/#/R-CEL-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Caenorhabditis elegans 58189 R-CEL-983259 https://reactome.org/PathwayBrowser/#/R-CEL-983259 Kinesins move along microtubules consuming ATP IEA Caenorhabditis elegans 58189 R-CEL-9846332 https://reactome.org/PathwayBrowser/#/R-CEL-9846332 FUT1,2 transfer fucose to gangliosides IEA Caenorhabditis elegans 58189 R-CFA-1008248 https://reactome.org/PathwayBrowser/#/R-CFA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Canis familiaris 58189 R-CFA-1028788 https://reactome.org/PathwayBrowser/#/R-CFA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Canis familiaris 58189 R-CFA-110133 https://reactome.org/PathwayBrowser/#/R-CFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Canis familiaris 58189 R-CFA-111524 https://reactome.org/PathwayBrowser/#/R-CFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Canis familiaris 58189 R-CFA-112037 https://reactome.org/PathwayBrowser/#/R-CFA-112037 Inactivation of PLC beta IEA Canis familiaris 58189 R-CFA-114544 https://reactome.org/PathwayBrowser/#/R-CFA-114544 p115-RhoGEF activation of RHOA IEA Canis familiaris 58189 R-CFA-114552 https://reactome.org/PathwayBrowser/#/R-CFA-114552 Thrombin-activated PARs activate G12/13 IEA Canis familiaris 58189 R-CFA-114558 https://reactome.org/PathwayBrowser/#/R-CFA-114558 Thrombin-activated PARs activate Gq IEA Canis familiaris 58189 R-CFA-1168636 https://reactome.org/PathwayBrowser/#/R-CFA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Canis familiaris 58189 R-CFA-1250383 https://reactome.org/PathwayBrowser/#/R-CFA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Canis familiaris 58189 R-CFA-1306972 https://reactome.org/PathwayBrowser/#/R-CFA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Canis familiaris 58189 R-CFA-1433415 https://reactome.org/PathwayBrowser/#/R-CFA-1433415 Activation of RAC1 IEA Canis familiaris 58189 R-CFA-1433471 https://reactome.org/PathwayBrowser/#/R-CFA-1433471 Activation of RAS by p-KIT bound SOS1 IEA Canis familiaris 58189 R-CFA-156913 https://reactome.org/PathwayBrowser/#/R-CFA-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Canis familiaris 58189 R-CFA-1638803 https://reactome.org/PathwayBrowser/#/R-CFA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Canis familiaris 58189 R-CFA-1638821 https://reactome.org/PathwayBrowser/#/R-CFA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Canis familiaris 58189 R-CFA-165195 https://reactome.org/PathwayBrowser/#/R-CFA-165195 GTP loading by Rheb IEA Canis familiaris 58189 R-CFA-165680 https://reactome.org/PathwayBrowser/#/R-CFA-165680 Formation of active mTORC1 complex IEA Canis familiaris 58189 R-CFA-165692 https://reactome.org/PathwayBrowser/#/R-CFA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Canis familiaris 58189 R-CFA-165718 https://reactome.org/PathwayBrowser/#/R-CFA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Canis familiaris 58189 R-CFA-167408 https://reactome.org/PathwayBrowser/#/R-CFA-167408 The high affinity receptor complex binds to G-protein IEA Canis familiaris 58189 R-CFA-167415 https://reactome.org/PathwayBrowser/#/R-CFA-167415 G-protein alpha subunit is inactivated IEA Canis familiaris 58189 R-CFA-167419 https://reactome.org/PathwayBrowser/#/R-CFA-167419 The receptor:G-protein complex releases GDP IEA Canis familiaris 58189 R-CFA-167433 https://reactome.org/PathwayBrowser/#/R-CFA-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Canis familiaris 58189 R-CFA-169904 https://reactome.org/PathwayBrowser/#/R-CFA-169904 C3G stimulates nucleotide exchange on Rap1 IEA Canis familiaris 58189 R-CFA-170026 https://reactome.org/PathwayBrowser/#/R-CFA-170026 Protons are translocated from the intermembrane space to the matrix IEA Canis familiaris 58189 R-CFA-170666 https://reactome.org/PathwayBrowser/#/R-CFA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Canis familiaris 58189 R-CFA-170674 https://reactome.org/PathwayBrowser/#/R-CFA-170674 Dissociation of the Gi alpha:G olf complex IEA Canis familiaris 58189 R-CFA-170677 https://reactome.org/PathwayBrowser/#/R-CFA-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Canis familiaris 58189 R-CFA-170685 https://reactome.org/PathwayBrowser/#/R-CFA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Canis familiaris 58189 R-CFA-170686 https://reactome.org/PathwayBrowser/#/R-CFA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Canis familiaris 58189 R-CFA-177938 https://reactome.org/PathwayBrowser/#/R-CFA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Canis familiaris 58189 R-CFA-177945 https://reactome.org/PathwayBrowser/#/R-CFA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Canis familiaris 58189 R-CFA-186834 https://reactome.org/PathwayBrowser/#/R-CFA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Canis familiaris 58189 R-CFA-190520 https://reactome.org/PathwayBrowser/#/R-CFA-190520 Association of Golgi transport vesicles with microtubules IEA Canis familiaris 58189 R-CFA-193646 https://reactome.org/PathwayBrowser/#/R-CFA-193646 NGF binding to p75NTR inactivates RHOA IEA Canis familiaris 58189 R-CFA-193668 https://reactome.org/PathwayBrowser/#/R-CFA-193668 p75NTR and RHOA-GDI interact IEA Canis familiaris 58189 R-CFA-193696 https://reactome.org/PathwayBrowser/#/R-CFA-193696 The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA IEA Canis familiaris 58189 R-CFA-194518 https://reactome.org/PathwayBrowser/#/R-CFA-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Canis familiaris 58189 R-CFA-2029451 https://reactome.org/PathwayBrowser/#/R-CFA-2029451 Activation of RAC1 by VAV IEA Canis familiaris 58189 R-CFA-2029467 https://reactome.org/PathwayBrowser/#/R-CFA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Canis familiaris 58189 R-CFA-203977 https://reactome.org/PathwayBrowser/#/R-CFA-203977 SAR1 Activation And Membrane Binding IEA Canis familiaris 58189 R-CFA-205039 https://reactome.org/PathwayBrowser/#/R-CFA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Canis familiaris 58189 R-CFA-210977 https://reactome.org/PathwayBrowser/#/R-CFA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Canis familiaris 58189 R-CFA-2130641 https://reactome.org/PathwayBrowser/#/R-CFA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Canis familiaris 58189 R-CFA-2130725 https://reactome.org/PathwayBrowser/#/R-CFA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Canis familiaris 58189 R-CFA-2179407 https://reactome.org/PathwayBrowser/#/R-CFA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Canis familiaris 58189 R-CFA-2213248 https://reactome.org/PathwayBrowser/#/R-CFA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Canis familiaris 58189 R-CFA-2424476 https://reactome.org/PathwayBrowser/#/R-CFA-2424476 Activation of RAC1 by VAV2/3 IEA Canis familiaris 58189 R-CFA-2424477 https://reactome.org/PathwayBrowser/#/R-CFA-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Canis familiaris 58189 R-CFA-2467809 https://reactome.org/PathwayBrowser/#/R-CFA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Canis familiaris 58189 R-CFA-2467811 https://reactome.org/PathwayBrowser/#/R-CFA-2467811 Separation of sister chromatids IEA Canis familiaris 58189 R-CFA-2468287 https://reactome.org/PathwayBrowser/#/R-CFA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Canis familiaris 58189 R-CFA-2484822 https://reactome.org/PathwayBrowser/#/R-CFA-2484822 Kinetochore assembly IEA Canis familiaris 58189 R-CFA-2584246 https://reactome.org/PathwayBrowser/#/R-CFA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Canis familiaris 58189 R-CFA-2730840 https://reactome.org/PathwayBrowser/#/R-CFA-2730840 Activation of RAC1 by VAV IEA Canis familiaris 58189 R-CFA-350769 https://reactome.org/PathwayBrowser/#/R-CFA-350769 trans-Golgi Network Coat Activation IEA Canis familiaris 58189 R-CFA-354173 https://reactome.org/PathwayBrowser/#/R-CFA-354173 Activation of Rap1 by cytosolic GEFs IEA Canis familiaris 58189 R-CFA-372819 https://reactome.org/PathwayBrowser/#/R-CFA-372819 PCK2 phosphorylates OA to yield PEP IEA Canis familiaris 58189 R-CFA-375302 https://reactome.org/PathwayBrowser/#/R-CFA-375302 Kinetochore capture of astral microtubules IEA Canis familiaris 58189 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 58189 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 58189 R-CFA-380316 https://reactome.org/PathwayBrowser/#/R-CFA-380316 Association of NuMA with microtubules IEA Canis familiaris 58189 R-CFA-380979 https://reactome.org/PathwayBrowser/#/R-CFA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Canis familiaris 58189 R-CFA-381612 https://reactome.org/PathwayBrowser/#/R-CFA-381612 GLP1R binds GLP1 IEA Canis familiaris 58189 R-CFA-381727 https://reactome.org/PathwayBrowser/#/R-CFA-381727 RAP1A exchanges GDP for GTP IEA Canis familiaris 58189 R-CFA-389348 https://reactome.org/PathwayBrowser/#/R-CFA-389348 Activation of Rac1 by pVav1 IEA Canis familiaris 58189 R-CFA-389350 https://reactome.org/PathwayBrowser/#/R-CFA-389350 Activation of Cdc42 by pVav1 IEA Canis familiaris 58189 R-CFA-392054 https://reactome.org/PathwayBrowser/#/R-CFA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Canis familiaris 58189 R-CFA-392195 https://reactome.org/PathwayBrowser/#/R-CFA-392195 Gi activation by P2Y purinoceptor 12 IEA Canis familiaris 58189 R-CFA-392513 https://reactome.org/PathwayBrowser/#/R-CFA-392513 Rap1 signal termination by Rap1GAPs IEA Canis familiaris 58189 R-CFA-3928592 https://reactome.org/PathwayBrowser/#/R-CFA-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Canis familiaris 58189 R-CFA-3928628 https://reactome.org/PathwayBrowser/#/R-CFA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 58189 R-CFA-3928642 https://reactome.org/PathwayBrowser/#/R-CFA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 58189 R-CFA-3928651 https://reactome.org/PathwayBrowser/#/R-CFA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Canis familiaris 58189 R-CFA-392870 https://reactome.org/PathwayBrowser/#/R-CFA-392870 Gs activation by prostacyclin receptor IEA Canis familiaris 58189 R-CFA-3965444 https://reactome.org/PathwayBrowser/#/R-CFA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Canis familiaris 58189 R-CFA-400092 https://reactome.org/PathwayBrowser/#/R-CFA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Canis familiaris 58189 R-CFA-4093336 https://reactome.org/PathwayBrowser/#/R-CFA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 58189 R-CFA-4093339 https://reactome.org/PathwayBrowser/#/R-CFA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Canis familiaris 58189 R-CFA-416530 https://reactome.org/PathwayBrowser/#/R-CFA-416530 FFAR1:FFAR1 ligands activate Gq IEA Canis familiaris 58189 R-CFA-416559 https://reactome.org/PathwayBrowser/#/R-CFA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Canis familiaris 58189 R-CFA-416588 https://reactome.org/PathwayBrowser/#/R-CFA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Canis familiaris 58189 R-CFA-418850 https://reactome.org/PathwayBrowser/#/R-CFA-418850 Activation of Cdc42 IEA Canis familiaris 58189 R-CFA-418856 https://reactome.org/PathwayBrowser/#/R-CFA-418856 Activation of Rac1 IEA Canis familiaris 58189 R-CFA-419166 https://reactome.org/PathwayBrowser/#/R-CFA-419166 GEFs activate RhoA,B,C IEA Canis familiaris 58189 R-CFA-420883 https://reactome.org/PathwayBrowser/#/R-CFA-420883 Opsins act as GEFs for G alpha-t IEA Canis familiaris 58189 R-CFA-421831 https://reactome.org/PathwayBrowser/#/R-CFA-421831 trans-Golgi Network Coat Assembly IEA Canis familiaris 58189 R-CFA-421835 https://reactome.org/PathwayBrowser/#/R-CFA-421835 trans-Golgi Network Vesicle Scission IEA Canis familiaris 58189 R-CFA-428750 https://reactome.org/PathwayBrowser/#/R-CFA-428750 Gq activation by TP receptor IEA Canis familiaris 58189 R-CFA-428917 https://reactome.org/PathwayBrowser/#/R-CFA-428917 G13 activation by TP receptor IEA Canis familiaris 58189 R-CFA-432195 https://reactome.org/PathwayBrowser/#/R-CFA-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Canis familiaris 58189 R-CFA-432706 https://reactome.org/PathwayBrowser/#/R-CFA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Canis familiaris 58189 R-CFA-432707 https://reactome.org/PathwayBrowser/#/R-CFA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Canis familiaris 58189 R-CFA-442273 https://reactome.org/PathwayBrowser/#/R-CFA-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Canis familiaris 58189 R-CFA-442291 https://reactome.org/PathwayBrowser/#/R-CFA-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Canis familiaris 58189 R-CFA-442314 https://reactome.org/PathwayBrowser/#/R-CFA-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Canis familiaris 58189 R-CFA-445064 https://reactome.org/PathwayBrowser/#/R-CFA-445064 Activation of Rac1 by VAV2 IEA Canis familiaris 58189 R-CFA-446208 https://reactome.org/PathwayBrowser/#/R-CFA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Canis familiaris 58189 R-CFA-446218 https://reactome.org/PathwayBrowser/#/R-CFA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Canis familiaris 58189 R-CFA-447074 https://reactome.org/PathwayBrowser/#/R-CFA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Canis familiaris 58189 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 58189 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 58189 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 58189 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 58189 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 58189 R-CFA-5218839 https://reactome.org/PathwayBrowser/#/R-CFA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Canis familiaris 58189 R-CFA-5218850 https://reactome.org/PathwayBrowser/#/R-CFA-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 58189 R-CFA-5419271 https://reactome.org/PathwayBrowser/#/R-CFA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Canis familiaris 58189 R-CFA-5419273 https://reactome.org/PathwayBrowser/#/R-CFA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Canis familiaris 58189 R-CFA-555065 https://reactome.org/PathwayBrowser/#/R-CFA-555065 Formation of clathrin coated vesicle IEA Canis familiaris 58189 R-CFA-5610733 https://reactome.org/PathwayBrowser/#/R-CFA-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Canis familiaris 58189 R-CFA-5610767 https://reactome.org/PathwayBrowser/#/R-CFA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Canis familiaris 58189 R-CFA-5617816 https://reactome.org/PathwayBrowser/#/R-CFA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Canis familiaris 58189 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 58189 R-CFA-5618328 https://reactome.org/PathwayBrowser/#/R-CFA-5618328 ATAT acetylates microtubules IEA Canis familiaris 58189 R-CFA-5618331 https://reactome.org/PathwayBrowser/#/R-CFA-5618331 HDAC6 deacetylates microtubules IEA Canis familiaris 58189 R-CFA-5623508 https://reactome.org/PathwayBrowser/#/R-CFA-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Canis familiaris 58189 R-CFA-5623513 https://reactome.org/PathwayBrowser/#/R-CFA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Canis familiaris 58189 R-CFA-5623519 https://reactome.org/PathwayBrowser/#/R-CFA-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Canis familiaris 58189 R-CFA-5623521 https://reactome.org/PathwayBrowser/#/R-CFA-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Canis familiaris 58189 R-CFA-5624949 https://reactome.org/PathwayBrowser/#/R-CFA-5624949 Assembly of the anterograde IFT train IEA Canis familiaris 58189 R-CFA-5624952 https://reactome.org/PathwayBrowser/#/R-CFA-5624952 Assembly of the retrograde IFT train IEA Canis familiaris 58189 R-CFA-5625416 https://reactome.org/PathwayBrowser/#/R-CFA-5625416 Anterograde IFT IEA Canis familiaris 58189 R-CFA-5625421 https://reactome.org/PathwayBrowser/#/R-CFA-5625421 The anterograde IFT train dissociates IEA Canis familiaris 58189 R-CFA-5625424 https://reactome.org/PathwayBrowser/#/R-CFA-5625424 The retrograde IFT train dissociates IEA Canis familiaris 58189 R-CFA-5625426 https://reactome.org/PathwayBrowser/#/R-CFA-5625426 Retrograde IFT IEA Canis familiaris 58189 R-CFA-5653957 https://reactome.org/PathwayBrowser/#/R-CFA-5653957 Rag dimer formation IEA Canis familiaris 58189 R-CFA-5653968 https://reactome.org/PathwayBrowser/#/R-CFA-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Canis familiaris 58189 R-CFA-5653974 https://reactome.org/PathwayBrowser/#/R-CFA-5653974 Ragulator binds Rag dimers IEA Canis familiaris 58189 R-CFA-5654392 https://reactome.org/PathwayBrowser/#/R-CFA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-5654402 https://reactome.org/PathwayBrowser/#/R-CFA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-5654413 https://reactome.org/PathwayBrowser/#/R-CFA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-5654426 https://reactome.org/PathwayBrowser/#/R-CFA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-5654600 https://reactome.org/PathwayBrowser/#/R-CFA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-5654618 https://reactome.org/PathwayBrowser/#/R-CFA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-5654647 https://reactome.org/PathwayBrowser/#/R-CFA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-5654663 https://reactome.org/PathwayBrowser/#/R-CFA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-5658231 https://reactome.org/PathwayBrowser/#/R-CFA-5658231 RAS GAPs stimulate RAS GTPase activity IEA Canis familiaris 58189 R-CFA-5665809 https://reactome.org/PathwayBrowser/#/R-CFA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Canis familiaris 58189 R-CFA-5666169 https://reactome.org/PathwayBrowser/#/R-CFA-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Canis familiaris 58189 R-CFA-5672010 https://reactome.org/PathwayBrowser/#/R-CFA-5672010 Active MTORC1 phosphorylates ULK1 IEA Canis familiaris 58189 R-CFA-5672017 https://reactome.org/PathwayBrowser/#/R-CFA-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Canis familiaris 58189 R-CFA-5672817 https://reactome.org/PathwayBrowser/#/R-CFA-5672817 Active MTORC1 binds the ULK1 complex IEA Canis familiaris 58189 R-CFA-5672828 https://reactome.org/PathwayBrowser/#/R-CFA-5672828 mTORC1 phosphorylates AKT1S1 IEA Canis familiaris 58189 R-CFA-5672843 https://reactome.org/PathwayBrowser/#/R-CFA-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Canis familiaris 58189 R-CFA-5672965 https://reactome.org/PathwayBrowser/#/R-CFA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-5673768 https://reactome.org/PathwayBrowser/#/R-CFA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Canis familiaris 58189 R-CFA-5675790 https://reactome.org/PathwayBrowser/#/R-CFA-5675790 MTORC1 dissociates from ULK complex IEA Canis familiaris 58189 R-CFA-5693925 https://reactome.org/PathwayBrowser/#/R-CFA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Canis familiaris 58189 R-CFA-5694409 https://reactome.org/PathwayBrowser/#/R-CFA-5694409 Nucleotide exchange on RAB1 IEA Canis familiaris 58189 R-CFA-5694439 https://reactome.org/PathwayBrowser/#/R-CFA-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Canis familiaris 58189 R-CFA-5694527 https://reactome.org/PathwayBrowser/#/R-CFA-5694527 Loss of SAR1B GTPase IEA Canis familiaris 58189 R-CFA-6788611 https://reactome.org/PathwayBrowser/#/R-CFA-6788611 HYKK phosphorylates 5HLYS IEA Canis familiaris 58189 R-CFA-6807866 https://reactome.org/PathwayBrowser/#/R-CFA-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Canis familiaris 58189 R-CFA-6807868 https://reactome.org/PathwayBrowser/#/R-CFA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Canis familiaris 58189 R-CFA-6807877 https://reactome.org/PathwayBrowser/#/R-CFA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Canis familiaris 58189 R-CFA-6809003 https://reactome.org/PathwayBrowser/#/R-CFA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Canis familiaris 58189 R-CFA-6809006 https://reactome.org/PathwayBrowser/#/R-CFA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Canis familiaris 58189 R-CFA-6809010 https://reactome.org/PathwayBrowser/#/R-CFA-6809010 COPI vesicle uncoating IEA Canis familiaris 58189 R-CFA-6811411 https://reactome.org/PathwayBrowser/#/R-CFA-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Canis familiaris 58189 R-CFA-6811414 https://reactome.org/PathwayBrowser/#/R-CFA-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Canis familiaris 58189 R-CFA-6811418 https://reactome.org/PathwayBrowser/#/R-CFA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Canis familiaris 58189 R-CFA-6811423 https://reactome.org/PathwayBrowser/#/R-CFA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Canis familiaris 58189 R-CFA-6811426 https://reactome.org/PathwayBrowser/#/R-CFA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Canis familiaris 58189 R-CFA-6811427 https://reactome.org/PathwayBrowser/#/R-CFA-6811427 COPI vesicle uncoating at the ER IEA Canis familiaris 58189 R-CFA-6814671 https://reactome.org/PathwayBrowser/#/R-CFA-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Canis familiaris 58189 R-CFA-6814833 https://reactome.org/PathwayBrowser/#/R-CFA-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Canis familiaris 58189 R-CFA-70241 https://reactome.org/PathwayBrowser/#/R-CFA-70241 PCK1 phosphorylates OA to yield PEP IEA Canis familiaris 58189 R-CFA-71775 https://reactome.org/PathwayBrowser/#/R-CFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Canis familiaris 58189 R-CFA-72619 https://reactome.org/PathwayBrowser/#/R-CFA-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Canis familiaris 58189 R-CFA-72670 https://reactome.org/PathwayBrowser/#/R-CFA-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Canis familiaris 58189 R-CFA-72671 https://reactome.org/PathwayBrowser/#/R-CFA-72671 eIF5B:GTP is hydrolyzed and released IEA Canis familiaris 58189 R-CFA-72722 https://reactome.org/PathwayBrowser/#/R-CFA-72722 eIF2 activation IEA Canis familiaris 58189 R-CFA-73788 https://reactome.org/PathwayBrowser/#/R-CFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Canis familiaris 58189 R-CFA-749453 https://reactome.org/PathwayBrowser/#/R-CFA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Canis familiaris 58189 R-CFA-751029 https://reactome.org/PathwayBrowser/#/R-CFA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Canis familiaris 58189 R-CFA-8847883 https://reactome.org/PathwayBrowser/#/R-CFA-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Canis familiaris 58189 R-CFA-8848618 https://reactome.org/PathwayBrowser/#/R-CFA-8848618 Activation of RAC1 by the PXN:CRK complex IEA Canis familiaris 58189 R-CFA-8849082 https://reactome.org/PathwayBrowser/#/R-CFA-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Canis familiaris 58189 R-CFA-8850040 https://reactome.org/PathwayBrowser/#/R-CFA-8850040 RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER IEA Canis familiaris 58189 R-CFA-8850041 https://reactome.org/PathwayBrowser/#/R-CFA-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Canis familiaris 58189 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58189 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58189 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58189 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58189 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58189 R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58189 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58189 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58189 R-CFA-8851827 https://reactome.org/PathwayBrowser/#/R-CFA-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Canis familiaris 58189 R-CFA-8851877 https://reactome.org/PathwayBrowser/#/R-CFA-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Canis familiaris 58189 R-CFA-8851899 https://reactome.org/PathwayBrowser/#/R-CFA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Canis familiaris 58189 R-CFA-8852280 https://reactome.org/PathwayBrowser/#/R-CFA-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Canis familiaris 58189 R-CFA-8852298 https://reactome.org/PathwayBrowser/#/R-CFA-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Canis familiaris 58189 R-CFA-8852306 https://reactome.org/PathwayBrowser/#/R-CFA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Canis familiaris 58189 R-CFA-8854173 https://reactome.org/PathwayBrowser/#/R-CFA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Canis familiaris 58189 R-CFA-8854255 https://reactome.org/PathwayBrowser/#/R-CFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 58189 R-CFA-8854612 https://reactome.org/PathwayBrowser/#/R-CFA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Canis familiaris 58189 R-CFA-8865774 https://reactome.org/PathwayBrowser/#/R-CFA-8865774 TTLLs polyglutamylate tubulin IEA Canis familiaris 58189 R-CFA-8867370 https://reactome.org/PathwayBrowser/#/R-CFA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Canis familiaris 58189 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 58189 R-CFA-8868659 https://reactome.org/PathwayBrowser/#/R-CFA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Canis familiaris 58189 R-CFA-8868660 https://reactome.org/PathwayBrowser/#/R-CFA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Canis familiaris 58189 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 58189 R-CFA-8870466 https://reactome.org/PathwayBrowser/#/R-CFA-8870466 RGGT:CHM binds RABs IEA Canis familiaris 58189 R-CFA-8870469 https://reactome.org/PathwayBrowser/#/R-CFA-8870469 RGGT geranylgeranylates RAB proteins IEA Canis familiaris 58189 R-CFA-8871193 https://reactome.org/PathwayBrowser/#/R-CFA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Canis familiaris 58189 R-CFA-8871194 https://reactome.org/PathwayBrowser/#/R-CFA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Canis familiaris 58189 R-CFA-8875318 https://reactome.org/PathwayBrowser/#/R-CFA-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Canis familiaris 58189 R-CFA-8875320 https://reactome.org/PathwayBrowser/#/R-CFA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Canis familiaris 58189 R-CFA-8875568 https://reactome.org/PathwayBrowser/#/R-CFA-8875568 RAPGEF1 activates RAP1 IEA Canis familiaris 58189 R-CFA-8875591 https://reactome.org/PathwayBrowser/#/R-CFA-8875591 DOCK7 activates RAC1 IEA Canis familiaris 58189 R-CFA-8876188 https://reactome.org/PathwayBrowser/#/R-CFA-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Canis familiaris 58189 R-CFA-8876190 https://reactome.org/PathwayBrowser/#/R-CFA-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Canis familiaris 58189 R-CFA-8876191 https://reactome.org/PathwayBrowser/#/R-CFA-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Canis familiaris 58189 R-CFA-8876454 https://reactome.org/PathwayBrowser/#/R-CFA-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Canis familiaris 58189 R-CFA-8876615 https://reactome.org/PathwayBrowser/#/R-CFA-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Canis familiaris 58189 R-CFA-8877308 https://reactome.org/PathwayBrowser/#/R-CFA-8877308 MADD exchanges GTP for GDP on RAB27 IEA Canis familiaris 58189 R-CFA-8877451 https://reactome.org/PathwayBrowser/#/R-CFA-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Canis familiaris 58189 R-CFA-8877475 https://reactome.org/PathwayBrowser/#/R-CFA-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Canis familiaris 58189 R-CFA-8877612 https://reactome.org/PathwayBrowser/#/R-CFA-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Canis familiaris 58189 R-CFA-8877760 https://reactome.org/PathwayBrowser/#/R-CFA-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Canis familiaris 58189 R-CFA-8877813 https://reactome.org/PathwayBrowser/#/R-CFA-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Canis familiaris 58189 R-CFA-8877998 https://reactome.org/PathwayBrowser/#/R-CFA-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Canis familiaris 58189 R-CFA-8941613 https://reactome.org/PathwayBrowser/#/R-CFA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-8941618 https://reactome.org/PathwayBrowser/#/R-CFA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-8941623 https://reactome.org/PathwayBrowser/#/R-CFA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-8941628 https://reactome.org/PathwayBrowser/#/R-CFA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris 58189 R-CFA-8944454 https://reactome.org/PathwayBrowser/#/R-CFA-8944454 mTORC1 phosphorylates MAF1 IEA Canis familiaris 58189 R-CFA-8944457 https://reactome.org/PathwayBrowser/#/R-CFA-8944457 MAF1 translocates to the nucleus IEA Canis familiaris 58189 R-CFA-8951498 https://reactome.org/PathwayBrowser/#/R-CFA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Canis familiaris 58189 R-CFA-8951586 https://reactome.org/PathwayBrowser/#/R-CFA-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Canis familiaris 58189 R-CFA-8952716 https://reactome.org/PathwayBrowser/#/R-CFA-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Canis familiaris 58189 R-CFA-8952726 https://reactome.org/PathwayBrowser/#/R-CFA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Canis familiaris 58189 R-CFA-8980691 https://reactome.org/PathwayBrowser/#/R-CFA-8980691 RHOA GEFs activate RHOA IEA Canis familiaris 58189 R-CFA-8981353 https://reactome.org/PathwayBrowser/#/R-CFA-8981353 RASA1 stimulates RAS GTPase activity IEA Canis familiaris 58189 R-CFA-8981637 https://reactome.org/PathwayBrowser/#/R-CFA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Canis familiaris 58189 R-CFA-8982012 https://reactome.org/PathwayBrowser/#/R-CFA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Canis familiaris 58189 R-CFA-8982018 https://reactome.org/PathwayBrowser/#/R-CFA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Canis familiaris 58189 R-CFA-8982020 https://reactome.org/PathwayBrowser/#/R-CFA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Canis familiaris 58189 R-CFA-8982021 https://reactome.org/PathwayBrowser/#/R-CFA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Canis familiaris 58189 R-CFA-8982025 https://reactome.org/PathwayBrowser/#/R-CFA-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Canis familiaris 58189 R-CFA-8982026 https://reactome.org/PathwayBrowser/#/R-CFA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Canis familiaris 58189 R-CFA-8985594 https://reactome.org/PathwayBrowser/#/R-CFA-8985594 MYO9B inactivates RHOA IEA Canis familiaris 58189 R-CFA-9012761 https://reactome.org/PathwayBrowser/#/R-CFA-9012761 The p75NTR:NgR:MDGI binds RHOA-GDI IEA Canis familiaris 58189 R-CFA-9012835 https://reactome.org/PathwayBrowser/#/R-CFA-9012835 GDIs block activation of RHOA IEA Canis familiaris 58189 R-CFA-9013021 https://reactome.org/PathwayBrowser/#/R-CFA-9013021 GDIs block activation of RHOB IEA Canis familiaris 58189 R-CFA-9013022 https://reactome.org/PathwayBrowser/#/R-CFA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Canis familiaris 58189 R-CFA-9013023 https://reactome.org/PathwayBrowser/#/R-CFA-9013023 RHOB GEFs activate RHOB IEA Canis familiaris 58189 R-CFA-9013108 https://reactome.org/PathwayBrowser/#/R-CFA-9013108 GDIs block activation of RHOC IEA Canis familiaris 58189 R-CFA-9013109 https://reactome.org/PathwayBrowser/#/R-CFA-9013109 RHOC GEFs activate RHOC IEA Canis familiaris 58189 R-CFA-9013111 https://reactome.org/PathwayBrowser/#/R-CFA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Canis familiaris 58189 R-CFA-9013143 https://reactome.org/PathwayBrowser/#/R-CFA-9013143 RAC1 GEFs activate RAC1 IEA Canis familiaris 58189 R-CFA-9013144 https://reactome.org/PathwayBrowser/#/R-CFA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Canis familiaris 58189 R-CFA-9013147 https://reactome.org/PathwayBrowser/#/R-CFA-9013147 RAC1 GDIs block activation of RAC1 IEA Canis familiaris 58189 R-CFA-9013158 https://reactome.org/PathwayBrowser/#/R-CFA-9013158 CDC42 GDIs block activation of CDC42 IEA Canis familiaris 58189 R-CFA-9013159 https://reactome.org/PathwayBrowser/#/R-CFA-9013159 CDC42 GEFs activate CDC42 IEA Canis familiaris 58189 R-CFA-9013161 https://reactome.org/PathwayBrowser/#/R-CFA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Canis familiaris 58189 R-CFA-9013435 https://reactome.org/PathwayBrowser/#/R-CFA-9013435 RHOD auto-activates IEA Canis familiaris 58189 R-CFA-9013437 https://reactome.org/PathwayBrowser/#/R-CFA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Canis familiaris 58189 R-CFA-9014293 https://reactome.org/PathwayBrowser/#/R-CFA-9014293 RAC2 GDIs block activation of RAC2 IEA Canis familiaris 58189 R-CFA-9014295 https://reactome.org/PathwayBrowser/#/R-CFA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Canis familiaris 58189 R-CFA-9014296 https://reactome.org/PathwayBrowser/#/R-CFA-9014296 RAC2 GEFs activate RAC2 IEA Canis familiaris 58189 R-CFA-9014433 https://reactome.org/PathwayBrowser/#/R-CFA-9014433 RHOG GEFs activate RHOG IEA Canis familiaris 58189 R-CFA-9014434 https://reactome.org/PathwayBrowser/#/R-CFA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Canis familiaris 58189 R-CFA-9014456 https://reactome.org/PathwayBrowser/#/R-CFA-9014456 GDIs block activation of RHOG IEA Canis familiaris 58189 R-CFA-9017488 https://reactome.org/PathwayBrowser/#/R-CFA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Canis familiaris 58189 R-CFA-9017491 https://reactome.org/PathwayBrowser/#/R-CFA-9017491 RHOJ GEFs activate RHOJ IEA Canis familiaris 58189 R-CFA-9018745 https://reactome.org/PathwayBrowser/#/R-CFA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Canis familiaris 58189 R-CFA-9018747 https://reactome.org/PathwayBrowser/#/R-CFA-9018747 RHOQ GEFs activate RHOQ IEA Canis familiaris 58189 R-CFA-9018768 https://reactome.org/PathwayBrowser/#/R-CFA-9018768 RHOU auto-activates IEA Canis familiaris 58189 R-CFA-9018798 https://reactome.org/PathwayBrowser/#/R-CFA-9018798 RHOV binds GTP IEA Canis familiaris 58189 R-CFA-9018804 https://reactome.org/PathwayBrowser/#/R-CFA-9018804 RAC3 GEFs activate RAC3 IEA Canis familiaris 58189 R-CFA-9018806 https://reactome.org/PathwayBrowser/#/R-CFA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Canis familiaris 58189 R-CFA-9018807 https://reactome.org/PathwayBrowser/#/R-CFA-9018807 RAC3 GDIs block activation of RAC3 IEA Canis familiaris 58189 R-CFA-9018814 https://reactome.org/PathwayBrowser/#/R-CFA-9018814 RHOT1 hydrolyzes GTP IEA Canis familiaris 58189 R-CFA-9032798 https://reactome.org/PathwayBrowser/#/R-CFA-9032798 DOCK3 activates RAC1 IEA Canis familiaris 58189 R-CFA-9036301 https://reactome.org/PathwayBrowser/#/R-CFA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Canis familiaris 58189 R-CFA-9036307 https://reactome.org/PathwayBrowser/#/R-CFA-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Canis familiaris 58189 R-CFA-9036987 https://reactome.org/PathwayBrowser/#/R-CFA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Canis familiaris 58189 R-CFA-927789 https://reactome.org/PathwayBrowser/#/R-CFA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Canis familiaris 58189 R-CFA-927813 https://reactome.org/PathwayBrowser/#/R-CFA-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Canis familiaris 58189 R-CFA-927832 https://reactome.org/PathwayBrowser/#/R-CFA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Canis familiaris 58189 R-CFA-927836 https://reactome.org/PathwayBrowser/#/R-CFA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Canis familiaris 58189 R-CFA-927889 https://reactome.org/PathwayBrowser/#/R-CFA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Canis familiaris 58189 R-CFA-939265 https://reactome.org/PathwayBrowser/#/R-CFA-939265 Activation of Rap1 by membrane-associated GEFs IEA Canis familiaris 58189 R-CFA-9603982 https://reactome.org/PathwayBrowser/#/R-CFA-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Canis familiaris 58189 R-CFA-9603983 https://reactome.org/PathwayBrowser/#/R-CFA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Canis familiaris 58189 R-CFA-9603984 https://reactome.org/PathwayBrowser/#/R-CFA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Canis familiaris 58189 R-CFA-9603986 https://reactome.org/PathwayBrowser/#/R-CFA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Canis familiaris 58189 R-CFA-9605609 https://reactome.org/PathwayBrowser/#/R-CFA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Canis familiaris 58189 R-CFA-9605644 https://reactome.org/PathwayBrowser/#/R-CFA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Canis familiaris 58189 R-CFA-9605682 https://reactome.org/PathwayBrowser/#/R-CFA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Canis familiaris 58189 R-CFA-9607304 https://reactome.org/PathwayBrowser/#/R-CFA-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Canis familiaris 58189 R-CFA-9624845 https://reactome.org/PathwayBrowser/#/R-CFA-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Canis familiaris 58189 R-CFA-9624893 https://reactome.org/PathwayBrowser/#/R-CFA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Canis familiaris 58189 R-CFA-9632906 https://reactome.org/PathwayBrowser/#/R-CFA-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Canis familiaris 58189 R-CFA-9632918 https://reactome.org/PathwayBrowser/#/R-CFA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Canis familiaris 58189 R-CFA-9639286 https://reactome.org/PathwayBrowser/#/R-CFA-9639286 RRAGC,D exchanges GTP for GDP IEA Canis familiaris 58189 R-CFA-9640167 https://reactome.org/PathwayBrowser/#/R-CFA-9640167 RRAGA,B exchanges GDP for GTP IEA Canis familiaris 58189 R-CFA-9640168 https://reactome.org/PathwayBrowser/#/R-CFA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Canis familiaris 58189 R-CFA-9640175 https://reactome.org/PathwayBrowser/#/R-CFA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Canis familiaris 58189 R-CFA-9640195 https://reactome.org/PathwayBrowser/#/R-CFA-9640195 RRAGA,B hydrolyzes GTP IEA Canis familiaris 58189 R-CFA-9645598 https://reactome.org/PathwayBrowser/#/R-CFA-9645598 RRAGC,D hydrolyzes GTP IEA Canis familiaris 58189 R-CFA-9645608 https://reactome.org/PathwayBrowser/#/R-CFA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Canis familiaris 58189 R-CFA-9646468 https://reactome.org/PathwayBrowser/#/R-CFA-9646468 mTORC1 binds RHEB:GTP IEA Canis familiaris 58189 R-CFA-9646679 https://reactome.org/PathwayBrowser/#/R-CFA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Canis familiaris 58189 R-CFA-9646685 https://reactome.org/PathwayBrowser/#/R-CFA-9646685 Aggresome dissociates from dynein and microtubule IEA Canis familiaris 58189 R-CFA-9648017 https://reactome.org/PathwayBrowser/#/R-CFA-9648017 EML4 binds to microtubules IEA Canis familiaris 58189 R-CFA-9648114 https://reactome.org/PathwayBrowser/#/R-CFA-9648114 EML4 recruits NUDC to mitotic spindle IEA Canis familiaris 58189 R-CFA-9649733 https://reactome.org/PathwayBrowser/#/R-CFA-9649733 mature p21 RAS binds GDP IEA Canis familiaris 58189 R-CFA-9649735 https://reactome.org/PathwayBrowser/#/R-CFA-9649735 Intrinsic nucleotide exchange on RAS IEA Canis familiaris 58189 R-CFA-9649736 https://reactome.org/PathwayBrowser/#/R-CFA-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Canis familiaris 58189 R-CFA-9668419 https://reactome.org/PathwayBrowser/#/R-CFA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Canis familiaris 58189 R-CFA-9693111 https://reactome.org/PathwayBrowser/#/R-CFA-9693111 RHOF auto-activates IEA Canis familiaris 58189 R-CFA-9693282 https://reactome.org/PathwayBrowser/#/R-CFA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Canis familiaris 58189 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 58189 R-CFA-9717206 https://reactome.org/PathwayBrowser/#/R-CFA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Canis familiaris 58189 R-CFA-9726862 https://reactome.org/PathwayBrowser/#/R-CFA-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Canis familiaris 58189 R-CFA-9728664 https://reactome.org/PathwayBrowser/#/R-CFA-9728664 GLP1R binds GLP1R agonists IEA Canis familiaris 58189 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 58189 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 58189 R-CFA-9751201 https://reactome.org/PathwayBrowser/#/R-CFA-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Canis familiaris 58189 R-CFA-983259 https://reactome.org/PathwayBrowser/#/R-CFA-983259 Kinesins move along microtubules consuming ATP IEA Canis familiaris 58189 R-CFA-983266 https://reactome.org/PathwayBrowser/#/R-CFA-983266 Kinesins bind microtubules IEA Canis familiaris 58189 R-CFA-983422 https://reactome.org/PathwayBrowser/#/R-CFA-983422 Disassembly of COPII coated vesicle IEA Canis familiaris 58189 R-CFA-9836404 https://reactome.org/PathwayBrowser/#/R-CFA-9836404 p-PKR dimer phosphorylates MAPT IEA Canis familiaris 58189 R-CFA-9846332 https://reactome.org/PathwayBrowser/#/R-CFA-9846332 FUT1,2 transfer fucose to gangliosides IEA Canis familiaris 58189 R-DDI-1008248 https://reactome.org/PathwayBrowser/#/R-DDI-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Dictyostelium discoideum 58189 R-DDI-110133 https://reactome.org/PathwayBrowser/#/R-DDI-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Dictyostelium discoideum 58189 R-DDI-111524 https://reactome.org/PathwayBrowser/#/R-DDI-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Dictyostelium discoideum 58189 R-DDI-112037 https://reactome.org/PathwayBrowser/#/R-DDI-112037 Inactivation of PLC beta IEA Dictyostelium discoideum 58189 R-DDI-156913 https://reactome.org/PathwayBrowser/#/R-DDI-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Dictyostelium discoideum 58189 R-DDI-165195 https://reactome.org/PathwayBrowser/#/R-DDI-165195 GTP loading by Rheb IEA Dictyostelium discoideum 58189 R-DDI-165680 https://reactome.org/PathwayBrowser/#/R-DDI-165680 Formation of active mTORC1 complex IEA Dictyostelium discoideum 58189 R-DDI-165692 https://reactome.org/PathwayBrowser/#/R-DDI-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Dictyostelium discoideum 58189 R-DDI-165718 https://reactome.org/PathwayBrowser/#/R-DDI-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Dictyostelium discoideum 58189 R-DDI-167415 https://reactome.org/PathwayBrowser/#/R-DDI-167415 G-protein alpha subunit is inactivated IEA Dictyostelium discoideum 58189 R-DDI-170666 https://reactome.org/PathwayBrowser/#/R-DDI-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Dictyostelium discoideum 58189 R-DDI-170674 https://reactome.org/PathwayBrowser/#/R-DDI-170674 Dissociation of the Gi alpha:G olf complex IEA Dictyostelium discoideum 58189 R-DDI-170677 https://reactome.org/PathwayBrowser/#/R-DDI-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Dictyostelium discoideum 58189 R-DDI-170685 https://reactome.org/PathwayBrowser/#/R-DDI-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Dictyostelium discoideum 58189 R-DDI-170686 https://reactome.org/PathwayBrowser/#/R-DDI-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Dictyostelium discoideum 58189 R-DDI-203977 https://reactome.org/PathwayBrowser/#/R-DDI-203977 SAR1 Activation And Membrane Binding IEA Dictyostelium discoideum 58189 R-DDI-205039 https://reactome.org/PathwayBrowser/#/R-DDI-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Dictyostelium discoideum 58189 R-DDI-350769 https://reactome.org/PathwayBrowser/#/R-DDI-350769 trans-Golgi Network Coat Activation IEA Dictyostelium discoideum 58189 R-DDI-354173 https://reactome.org/PathwayBrowser/#/R-DDI-354173 Activation of Rap1 by cytosolic GEFs IEA Dictyostelium discoideum 58189 R-DDI-372819 https://reactome.org/PathwayBrowser/#/R-DDI-372819 PCK2 phosphorylates OA to yield PEP IEA Dictyostelium discoideum 58189 R-DDI-377186 https://reactome.org/PathwayBrowser/#/R-DDI-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Dictyostelium discoideum 58189 R-DDI-380073 https://reactome.org/PathwayBrowser/#/R-DDI-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Dictyostelium discoideum 58189 R-DDI-380979 https://reactome.org/PathwayBrowser/#/R-DDI-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Dictyostelium discoideum 58189 R-DDI-381727 https://reactome.org/PathwayBrowser/#/R-DDI-381727 RAP1A exchanges GDP for GTP IEA Dictyostelium discoideum 58189 R-DDI-392513 https://reactome.org/PathwayBrowser/#/R-DDI-392513 Rap1 signal termination by Rap1GAPs IEA Dictyostelium discoideum 58189 R-DDI-446208 https://reactome.org/PathwayBrowser/#/R-DDI-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Dictyostelium discoideum 58189 R-DDI-446218 https://reactome.org/PathwayBrowser/#/R-DDI-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Dictyostelium discoideum 58189 R-DDI-447074 https://reactome.org/PathwayBrowser/#/R-DDI-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Dictyostelium discoideum 58189 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 58189 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 58189 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 58189 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 58189 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 58189 R-DDI-5610733 https://reactome.org/PathwayBrowser/#/R-DDI-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Dictyostelium discoideum 58189 R-DDI-5618331 https://reactome.org/PathwayBrowser/#/R-DDI-5618331 HDAC6 deacetylates microtubules IEA Dictyostelium discoideum 58189 R-DDI-5623508 https://reactome.org/PathwayBrowser/#/R-DDI-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Dictyostelium discoideum 58189 R-DDI-5653957 https://reactome.org/PathwayBrowser/#/R-DDI-5653957 Rag dimer formation IEA Dictyostelium discoideum 58189 R-DDI-5653968 https://reactome.org/PathwayBrowser/#/R-DDI-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Dictyostelium discoideum 58189 R-DDI-5653974 https://reactome.org/PathwayBrowser/#/R-DDI-5653974 Ragulator binds Rag dimers IEA Dictyostelium discoideum 58189 R-DDI-5672010 https://reactome.org/PathwayBrowser/#/R-DDI-5672010 Active MTORC1 phosphorylates ULK1 IEA Dictyostelium discoideum 58189 R-DDI-5672017 https://reactome.org/PathwayBrowser/#/R-DDI-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Dictyostelium discoideum 58189 R-DDI-5672329 https://reactome.org/PathwayBrowser/#/R-DDI-5672329 IQGAP1 binds CLIP1 and microtubules IEA Dictyostelium discoideum 58189 R-DDI-5672817 https://reactome.org/PathwayBrowser/#/R-DDI-5672817 Active MTORC1 binds the ULK1 complex IEA Dictyostelium discoideum 58189 R-DDI-5672828 https://reactome.org/PathwayBrowser/#/R-DDI-5672828 mTORC1 phosphorylates AKT1S1 IEA Dictyostelium discoideum 58189 R-DDI-5673768 https://reactome.org/PathwayBrowser/#/R-DDI-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Dictyostelium discoideum 58189 R-DDI-5675790 https://reactome.org/PathwayBrowser/#/R-DDI-5675790 MTORC1 dissociates from ULK complex IEA Dictyostelium discoideum 58189 R-DDI-5693925 https://reactome.org/PathwayBrowser/#/R-DDI-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Dictyostelium discoideum 58189 R-DDI-5694409 https://reactome.org/PathwayBrowser/#/R-DDI-5694409 Nucleotide exchange on RAB1 IEA Dictyostelium discoideum 58189 R-DDI-5694439 https://reactome.org/PathwayBrowser/#/R-DDI-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Dictyostelium discoideum 58189 R-DDI-5694527 https://reactome.org/PathwayBrowser/#/R-DDI-5694527 Loss of SAR1B GTPase IEA Dictyostelium discoideum 58189 R-DDI-6807866 https://reactome.org/PathwayBrowser/#/R-DDI-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Dictyostelium discoideum 58189 R-DDI-6807868 https://reactome.org/PathwayBrowser/#/R-DDI-6807868 GBF1 stimulates ARF nucleotide exchange IEA Dictyostelium discoideum 58189 R-DDI-6807877 https://reactome.org/PathwayBrowser/#/R-DDI-6807877 ARFGAPs stimulate ARF GTPase activity IEA Dictyostelium discoideum 58189 R-DDI-6809003 https://reactome.org/PathwayBrowser/#/R-DDI-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Dictyostelium discoideum 58189 R-DDI-6811411 https://reactome.org/PathwayBrowser/#/R-DDI-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Dictyostelium discoideum 58189 R-DDI-6811414 https://reactome.org/PathwayBrowser/#/R-DDI-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Dictyostelium discoideum 58189 R-DDI-6811418 https://reactome.org/PathwayBrowser/#/R-DDI-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Dictyostelium discoideum 58189 R-DDI-6811427 https://reactome.org/PathwayBrowser/#/R-DDI-6811427 COPI vesicle uncoating at the ER IEA Dictyostelium discoideum 58189 R-DDI-6811428 https://reactome.org/PathwayBrowser/#/R-DDI-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Dictyostelium discoideum 58189 R-DDI-6811429 https://reactome.org/PathwayBrowser/#/R-DDI-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Dictyostelium discoideum 58189 R-DDI-6814833 https://reactome.org/PathwayBrowser/#/R-DDI-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Dictyostelium discoideum 58189 R-DDI-70241 https://reactome.org/PathwayBrowser/#/R-DDI-70241 PCK1 phosphorylates OA to yield PEP IEA Dictyostelium discoideum 58189 R-DDI-71775 https://reactome.org/PathwayBrowser/#/R-DDI-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Dictyostelium discoideum 58189 R-DDI-72670 https://reactome.org/PathwayBrowser/#/R-DDI-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Dictyostelium discoideum 58189 R-DDI-72671 https://reactome.org/PathwayBrowser/#/R-DDI-72671 eIF5B:GTP is hydrolyzed and released IEA Dictyostelium discoideum 58189 R-DDI-72722 https://reactome.org/PathwayBrowser/#/R-DDI-72722 eIF2 activation IEA Dictyostelium discoideum 58189 R-DDI-73788 https://reactome.org/PathwayBrowser/#/R-DDI-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Dictyostelium discoideum 58189 R-DDI-8847534 https://reactome.org/PathwayBrowser/#/R-DDI-8847534 RAB43 hydrolyses GTP IEA Dictyostelium discoideum 58189 R-DDI-8847883 https://reactome.org/PathwayBrowser/#/R-DDI-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Dictyostelium discoideum 58189 R-DDI-8848618 https://reactome.org/PathwayBrowser/#/R-DDI-8848618 Activation of RAC1 by the PXN:CRK complex IEA Dictyostelium discoideum 58189 R-DDI-8850040 https://reactome.org/PathwayBrowser/#/R-DDI-8850040 RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER IEA Dictyostelium discoideum 58189 R-DDI-8850041 https://reactome.org/PathwayBrowser/#/R-DDI-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Dictyostelium discoideum 58189 R-DDI-8854173 https://reactome.org/PathwayBrowser/#/R-DDI-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Dictyostelium discoideum 58189 R-DDI-8854255 https://reactome.org/PathwayBrowser/#/R-DDI-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 58189 R-DDI-8854612 https://reactome.org/PathwayBrowser/#/R-DDI-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Dictyostelium discoideum 58189 R-DDI-8867370 https://reactome.org/PathwayBrowser/#/R-DDI-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Dictyostelium discoideum 58189 R-DDI-8870466 https://reactome.org/PathwayBrowser/#/R-DDI-8870466 RGGT:CHM binds RABs IEA Dictyostelium discoideum 58189 R-DDI-8870469 https://reactome.org/PathwayBrowser/#/R-DDI-8870469 RGGT geranylgeranylates RAB proteins IEA Dictyostelium discoideum 58189 R-DDI-8875320 https://reactome.org/PathwayBrowser/#/R-DDI-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Dictyostelium discoideum 58189 R-DDI-8876191 https://reactome.org/PathwayBrowser/#/R-DDI-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Dictyostelium discoideum 58189 R-DDI-8876193 https://reactome.org/PathwayBrowser/#/R-DDI-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Dictyostelium discoideum 58189 R-DDI-8876454 https://reactome.org/PathwayBrowser/#/R-DDI-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Dictyostelium discoideum 58189 R-DDI-8876615 https://reactome.org/PathwayBrowser/#/R-DDI-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Dictyostelium discoideum 58189 R-DDI-8876616 https://reactome.org/PathwayBrowser/#/R-DDI-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Dictyostelium discoideum 58189 R-DDI-8876837 https://reactome.org/PathwayBrowser/#/R-DDI-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Dictyostelium discoideum 58189 R-DDI-8877451 https://reactome.org/PathwayBrowser/#/R-DDI-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Dictyostelium discoideum 58189 R-DDI-8877475 https://reactome.org/PathwayBrowser/#/R-DDI-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Dictyostelium discoideum 58189 R-DDI-8877612 https://reactome.org/PathwayBrowser/#/R-DDI-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Dictyostelium discoideum 58189 R-DDI-8877998 https://reactome.org/PathwayBrowser/#/R-DDI-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Dictyostelium discoideum 58189 R-DDI-8938815 https://reactome.org/PathwayBrowser/#/R-DDI-8938815 RNF152 polyubiquitinates RRAGA IEA Dictyostelium discoideum 58189 R-DDI-8938829 https://reactome.org/PathwayBrowser/#/R-DDI-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 IEA Dictyostelium discoideum 58189 R-DDI-8944454 https://reactome.org/PathwayBrowser/#/R-DDI-8944454 mTORC1 phosphorylates MAF1 IEA Dictyostelium discoideum 58189 R-DDI-8944457 https://reactome.org/PathwayBrowser/#/R-DDI-8944457 MAF1 translocates to the nucleus IEA Dictyostelium discoideum 58189 R-DDI-8952726 https://reactome.org/PathwayBrowser/#/R-DDI-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Dictyostelium discoideum 58189 R-DDI-8982012 https://reactome.org/PathwayBrowser/#/R-DDI-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Dictyostelium discoideum 58189 R-DDI-8982018 https://reactome.org/PathwayBrowser/#/R-DDI-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Dictyostelium discoideum 58189 R-DDI-8982020 https://reactome.org/PathwayBrowser/#/R-DDI-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Dictyostelium discoideum 58189 R-DDI-8982021 https://reactome.org/PathwayBrowser/#/R-DDI-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Dictyostelium discoideum 58189 R-DDI-8982025 https://reactome.org/PathwayBrowser/#/R-DDI-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Dictyostelium discoideum 58189 R-DDI-8982026 https://reactome.org/PathwayBrowser/#/R-DDI-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Dictyostelium discoideum 58189 R-DDI-9013143 https://reactome.org/PathwayBrowser/#/R-DDI-9013143 RAC1 GEFs activate RAC1 IEA Dictyostelium discoideum 58189 R-DDI-9013144 https://reactome.org/PathwayBrowser/#/R-DDI-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Dictyostelium discoideum 58189 R-DDI-9013147 https://reactome.org/PathwayBrowser/#/R-DDI-9013147 RAC1 GDIs block activation of RAC1 IEA Dictyostelium discoideum 58189 R-DDI-9013158 https://reactome.org/PathwayBrowser/#/R-DDI-9013158 CDC42 GDIs block activation of CDC42 IEA Dictyostelium discoideum 58189 R-DDI-9013159 https://reactome.org/PathwayBrowser/#/R-DDI-9013159 CDC42 GEFs activate CDC42 IEA Dictyostelium discoideum 58189 R-DDI-9013161 https://reactome.org/PathwayBrowser/#/R-DDI-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Dictyostelium discoideum 58189 R-DDI-9014293 https://reactome.org/PathwayBrowser/#/R-DDI-9014293 RAC2 GDIs block activation of RAC2 IEA Dictyostelium discoideum 58189 R-DDI-9014295 https://reactome.org/PathwayBrowser/#/R-DDI-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Dictyostelium discoideum 58189 R-DDI-9014296 https://reactome.org/PathwayBrowser/#/R-DDI-9014296 RAC2 GEFs activate RAC2 IEA Dictyostelium discoideum 58189 R-DDI-9014433 https://reactome.org/PathwayBrowser/#/R-DDI-9014433 RHOG GEFs activate RHOG IEA Dictyostelium discoideum 58189 R-DDI-9014456 https://reactome.org/PathwayBrowser/#/R-DDI-9014456 GDIs block activation of RHOG IEA Dictyostelium discoideum 58189 R-DDI-9017488 https://reactome.org/PathwayBrowser/#/R-DDI-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Dictyostelium discoideum 58189 R-DDI-9017491 https://reactome.org/PathwayBrowser/#/R-DDI-9017491 RHOJ GEFs activate RHOJ IEA Dictyostelium discoideum 58189 R-DDI-9018745 https://reactome.org/PathwayBrowser/#/R-DDI-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Dictyostelium discoideum 58189 R-DDI-9018747 https://reactome.org/PathwayBrowser/#/R-DDI-9018747 RHOQ GEFs activate RHOQ IEA Dictyostelium discoideum 58189 R-DDI-9018768 https://reactome.org/PathwayBrowser/#/R-DDI-9018768 RHOU auto-activates IEA Dictyostelium discoideum 58189 R-DDI-9018798 https://reactome.org/PathwayBrowser/#/R-DDI-9018798 RHOV binds GTP IEA Dictyostelium discoideum 58189 R-DDI-9018804 https://reactome.org/PathwayBrowser/#/R-DDI-9018804 RAC3 GEFs activate RAC3 IEA Dictyostelium discoideum 58189 R-DDI-9018806 https://reactome.org/PathwayBrowser/#/R-DDI-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Dictyostelium discoideum 58189 R-DDI-9018807 https://reactome.org/PathwayBrowser/#/R-DDI-9018807 RAC3 GDIs block activation of RAC3 IEA Dictyostelium discoideum 58189 R-DDI-9018814 https://reactome.org/PathwayBrowser/#/R-DDI-9018814 RHOT1 hydrolyzes GTP IEA Dictyostelium discoideum 58189 R-DDI-9018826 https://reactome.org/PathwayBrowser/#/R-DDI-9018826 RHOT2 hydrolyzes GTP IEA Dictyostelium discoideum 58189 R-DDI-927789 https://reactome.org/PathwayBrowser/#/R-DDI-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Dictyostelium discoideum 58189 R-DDI-927832 https://reactome.org/PathwayBrowser/#/R-DDI-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Dictyostelium discoideum 58189 R-DDI-927889 https://reactome.org/PathwayBrowser/#/R-DDI-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Dictyostelium discoideum 58189 R-DDI-939265 https://reactome.org/PathwayBrowser/#/R-DDI-939265 Activation of Rap1 by membrane-associated GEFs IEA Dictyostelium discoideum 58189 R-DDI-9603984 https://reactome.org/PathwayBrowser/#/R-DDI-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Dictyostelium discoideum 58189 R-DDI-9603986 https://reactome.org/PathwayBrowser/#/R-DDI-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Dictyostelium discoideum 58189 R-DDI-9605609 https://reactome.org/PathwayBrowser/#/R-DDI-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Dictyostelium discoideum 58189 R-DDI-9605644 https://reactome.org/PathwayBrowser/#/R-DDI-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Dictyostelium discoideum 58189 R-DDI-9605682 https://reactome.org/PathwayBrowser/#/R-DDI-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Dictyostelium discoideum 58189 R-DDI-9624845 https://reactome.org/PathwayBrowser/#/R-DDI-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Dictyostelium discoideum 58189 R-DDI-9639286 https://reactome.org/PathwayBrowser/#/R-DDI-9639286 RRAGC,D exchanges GTP for GDP IEA Dictyostelium discoideum 58189 R-DDI-9640167 https://reactome.org/PathwayBrowser/#/R-DDI-9640167 RRAGA,B exchanges GDP for GTP IEA Dictyostelium discoideum 58189 R-DDI-9640195 https://reactome.org/PathwayBrowser/#/R-DDI-9640195 RRAGA,B hydrolyzes GTP IEA Dictyostelium discoideum 58189 R-DDI-9645598 https://reactome.org/PathwayBrowser/#/R-DDI-9645598 RRAGC,D hydrolyzes GTP IEA Dictyostelium discoideum 58189 R-DDI-9645608 https://reactome.org/PathwayBrowser/#/R-DDI-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Dictyostelium discoideum 58189 R-DDI-9646468 https://reactome.org/PathwayBrowser/#/R-DDI-9646468 mTORC1 binds RHEB:GTP IEA Dictyostelium discoideum 58189 R-DDI-9646685 https://reactome.org/PathwayBrowser/#/R-DDI-9646685 Aggresome dissociates from dynein and microtubule IEA Dictyostelium discoideum 58189 R-DDI-9668419 https://reactome.org/PathwayBrowser/#/R-DDI-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Dictyostelium discoideum 58189 R-DDI-9726862 https://reactome.org/PathwayBrowser/#/R-DDI-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Dictyostelium discoideum 58189 R-DME-1008248 https://reactome.org/PathwayBrowser/#/R-DME-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Drosophila melanogaster 58189 R-DME-1028788 https://reactome.org/PathwayBrowser/#/R-DME-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Drosophila melanogaster 58189 R-DME-110133 https://reactome.org/PathwayBrowser/#/R-DME-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Drosophila melanogaster 58189 R-DME-110491 https://reactome.org/PathwayBrowser/#/R-DME-110491 DRheb is inhibited by the TSC1/2 complex TAS Drosophila melanogaster 58189 R-DME-111524 https://reactome.org/PathwayBrowser/#/R-DME-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Drosophila melanogaster 58189 R-DME-112037 https://reactome.org/PathwayBrowser/#/R-DME-112037 Inactivation of PLC beta IEA Drosophila melanogaster 58189 R-DME-114544 https://reactome.org/PathwayBrowser/#/R-DME-114544 p115-RhoGEF activation of RHOA IEA Drosophila melanogaster 58189 R-DME-1250383 https://reactome.org/PathwayBrowser/#/R-DME-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Drosophila melanogaster 58189 R-DME-1306972 https://reactome.org/PathwayBrowser/#/R-DME-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Drosophila melanogaster 58189 R-DME-1433415 https://reactome.org/PathwayBrowser/#/R-DME-1433415 Activation of RAC1 IEA Drosophila melanogaster 58189 R-DME-1433471 https://reactome.org/PathwayBrowser/#/R-DME-1433471 Activation of RAS by p-KIT bound SOS1 IEA Drosophila melanogaster 58189 R-DME-156913 https://reactome.org/PathwayBrowser/#/R-DME-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Drosophila melanogaster 58189 R-DME-165127 https://reactome.org/PathwayBrowser/#/R-DME-165127 GEF binds to the inactive DRheb TAS Drosophila melanogaster 58189 R-DME-165129 https://reactome.org/PathwayBrowser/#/R-DME-165129 GDP is exchanged for GTP on DRheb TAS Drosophila melanogaster 58189 R-DME-165195 https://reactome.org/PathwayBrowser/#/R-DME-165195 GTP loading by Rheb IEA Drosophila melanogaster 58189 R-DME-165680 https://reactome.org/PathwayBrowser/#/R-DME-165680 Formation of active mTORC1 complex IEA Drosophila melanogaster 58189 R-DME-165692 https://reactome.org/PathwayBrowser/#/R-DME-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Drosophila melanogaster 58189 R-DME-165718 https://reactome.org/PathwayBrowser/#/R-DME-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Drosophila melanogaster 58189 R-DME-167415 https://reactome.org/PathwayBrowser/#/R-DME-167415 G-protein alpha subunit is inactivated IEA Drosophila melanogaster 58189 R-DME-167419 https://reactome.org/PathwayBrowser/#/R-DME-167419 The receptor:G-protein complex releases GDP IEA Drosophila melanogaster 58189 R-DME-167433 https://reactome.org/PathwayBrowser/#/R-DME-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Drosophila melanogaster 58189 R-DME-170026 https://reactome.org/PathwayBrowser/#/R-DME-170026 Protons are translocated from the intermembrane space to the matrix IEA Drosophila melanogaster 58189 R-DME-170666 https://reactome.org/PathwayBrowser/#/R-DME-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Drosophila melanogaster 58189 R-DME-170674 https://reactome.org/PathwayBrowser/#/R-DME-170674 Dissociation of the Gi alpha:G olf complex IEA Drosophila melanogaster 58189 R-DME-170677 https://reactome.org/PathwayBrowser/#/R-DME-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Drosophila melanogaster 58189 R-DME-170685 https://reactome.org/PathwayBrowser/#/R-DME-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Drosophila melanogaster 58189 R-DME-170686 https://reactome.org/PathwayBrowser/#/R-DME-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Drosophila melanogaster 58189 R-DME-177938 https://reactome.org/PathwayBrowser/#/R-DME-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Drosophila melanogaster 58189 R-DME-177945 https://reactome.org/PathwayBrowser/#/R-DME-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Drosophila melanogaster 58189 R-DME-186834 https://reactome.org/PathwayBrowser/#/R-DME-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Drosophila melanogaster 58189 R-DME-194518 https://reactome.org/PathwayBrowser/#/R-DME-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Drosophila melanogaster 58189 R-DME-203977 https://reactome.org/PathwayBrowser/#/R-DME-203977 SAR1 Activation And Membrane Binding IEA Drosophila melanogaster 58189 R-DME-205039 https://reactome.org/PathwayBrowser/#/R-DME-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Drosophila melanogaster 58189 R-DME-2179407 https://reactome.org/PathwayBrowser/#/R-DME-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Drosophila melanogaster 58189 R-DME-2424476 https://reactome.org/PathwayBrowser/#/R-DME-2424476 Activation of RAC1 by VAV2/3 IEA Drosophila melanogaster 58189 R-DME-2424477 https://reactome.org/PathwayBrowser/#/R-DME-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Drosophila melanogaster 58189 R-DME-2730840 https://reactome.org/PathwayBrowser/#/R-DME-2730840 Activation of RAC1 by VAV IEA Drosophila melanogaster 58189 R-DME-350359 https://reactome.org/PathwayBrowser/#/R-DME-350359 RHO1:GDP complex dissociates from RHOGDI and binds to the plasma membrane TAS Drosophila melanogaster 58189 R-DME-350395 https://reactome.org/PathwayBrowser/#/R-DME-350395 RHOGDI binds to and sequesters RHO1:GDP complex to the cytosol TAS Drosophila melanogaster 58189 R-DME-350405 https://reactome.org/PathwayBrowser/#/R-DME-350405 RHOGEF2 binds to RHO1:GDP complex at the plasma membrane TAS Drosophila melanogaster 58189 R-DME-350410 https://reactome.org/PathwayBrowser/#/R-DME-350410 RHO1:GDP complex dissociates from RHOGAPP190 TAS Drosophila melanogaster 58189 R-DME-350458 https://reactome.org/PathwayBrowser/#/R-DME-350458 RHOGAPP190 activates GTP hydrolysis by RHO1:GTP TAS Drosophila melanogaster 58189 R-DME-350477 https://reactome.org/PathwayBrowser/#/R-DME-350477 RHOGEF2 stimulates nucleotide exchange of RHO1:GDP complex TAS Drosophila melanogaster 58189 R-DME-350769 https://reactome.org/PathwayBrowser/#/R-DME-350769 trans-Golgi Network Coat Activation IEA Drosophila melanogaster 58189 R-DME-372819 https://reactome.org/PathwayBrowser/#/R-DME-372819 PCK2 phosphorylates OA to yield PEP IEA Drosophila melanogaster 58189 R-DME-377186 https://reactome.org/PathwayBrowser/#/R-DME-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Drosophila melanogaster 58189 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 58189 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 58189 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 58189 R-DME-380979 https://reactome.org/PathwayBrowser/#/R-DME-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Drosophila melanogaster 58189 R-DME-381727 https://reactome.org/PathwayBrowser/#/R-DME-381727 RAP1A exchanges GDP for GTP IEA Drosophila melanogaster 58189 R-DME-392054 https://reactome.org/PathwayBrowser/#/R-DME-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Drosophila melanogaster 58189 R-DME-392195 https://reactome.org/PathwayBrowser/#/R-DME-392195 Gi activation by P2Y purinoceptor 12 IEA Drosophila melanogaster 58189 R-DME-392513 https://reactome.org/PathwayBrowser/#/R-DME-392513 Rap1 signal termination by Rap1GAPs IEA Drosophila melanogaster 58189 R-DME-3928592 https://reactome.org/PathwayBrowser/#/R-DME-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Drosophila melanogaster 58189 R-DME-3928628 https://reactome.org/PathwayBrowser/#/R-DME-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 58189 R-DME-3928642 https://reactome.org/PathwayBrowser/#/R-DME-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 58189 R-DME-3928651 https://reactome.org/PathwayBrowser/#/R-DME-3928651 NGEF exchanges GTP for GDP on RHOA IEA Drosophila melanogaster 58189 R-DME-392870 https://reactome.org/PathwayBrowser/#/R-DME-392870 Gs activation by prostacyclin receptor IEA Drosophila melanogaster 58189 R-DME-3965444 https://reactome.org/PathwayBrowser/#/R-DME-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-400092 https://reactome.org/PathwayBrowser/#/R-DME-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Drosophila melanogaster 58189 R-DME-4093336 https://reactome.org/PathwayBrowser/#/R-DME-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 58189 R-DME-4093339 https://reactome.org/PathwayBrowser/#/R-DME-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Drosophila melanogaster 58189 R-DME-416588 https://reactome.org/PathwayBrowser/#/R-DME-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Drosophila melanogaster 58189 R-DME-418850 https://reactome.org/PathwayBrowser/#/R-DME-418850 Activation of Cdc42 IEA Drosophila melanogaster 58189 R-DME-418856 https://reactome.org/PathwayBrowser/#/R-DME-418856 Activation of Rac1 IEA Drosophila melanogaster 58189 R-DME-419166 https://reactome.org/PathwayBrowser/#/R-DME-419166 GEFs activate RhoA,B,C IEA Drosophila melanogaster 58189 R-DME-421831 https://reactome.org/PathwayBrowser/#/R-DME-421831 trans-Golgi Network Coat Assembly IEA Drosophila melanogaster 58189 R-DME-421835 https://reactome.org/PathwayBrowser/#/R-DME-421835 trans-Golgi Network Vesicle Scission IEA Drosophila melanogaster 58189 R-DME-428520 https://reactome.org/PathwayBrowser/#/R-DME-428520 Inactivation of Rac1 TAS Drosophila melanogaster 58189 R-DME-428523 https://reactome.org/PathwayBrowser/#/R-DME-428523 Activation of Rac by Sos TAS Drosophila melanogaster 58189 R-DME-428750 https://reactome.org/PathwayBrowser/#/R-DME-428750 Gq activation by TP receptor IEA Drosophila melanogaster 58189 R-DME-428917 https://reactome.org/PathwayBrowser/#/R-DME-428917 G13 activation by TP receptor IEA Drosophila melanogaster 58189 R-DME-432706 https://reactome.org/PathwayBrowser/#/R-DME-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Drosophila melanogaster 58189 R-DME-432707 https://reactome.org/PathwayBrowser/#/R-DME-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Drosophila melanogaster 58189 R-DME-442273 https://reactome.org/PathwayBrowser/#/R-DME-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Drosophila melanogaster 58189 R-DME-442291 https://reactome.org/PathwayBrowser/#/R-DME-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Drosophila melanogaster 58189 R-DME-442314 https://reactome.org/PathwayBrowser/#/R-DME-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Drosophila melanogaster 58189 R-DME-445064 https://reactome.org/PathwayBrowser/#/R-DME-445064 Activation of Rac1 by VAV2 IEA Drosophila melanogaster 58189 R-DME-446208 https://reactome.org/PathwayBrowser/#/R-DME-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Drosophila melanogaster 58189 R-DME-446218 https://reactome.org/PathwayBrowser/#/R-DME-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Drosophila melanogaster 58189 R-DME-447074 https://reactome.org/PathwayBrowser/#/R-DME-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Drosophila melanogaster 58189 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 58189 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 58189 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 58189 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 58189 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 58189 R-DME-5218839 https://reactome.org/PathwayBrowser/#/R-DME-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Drosophila melanogaster 58189 R-DME-5218850 https://reactome.org/PathwayBrowser/#/R-DME-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 58189 R-DME-5419271 https://reactome.org/PathwayBrowser/#/R-DME-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Drosophila melanogaster 58189 R-DME-5419273 https://reactome.org/PathwayBrowser/#/R-DME-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Drosophila melanogaster 58189 R-DME-555065 https://reactome.org/PathwayBrowser/#/R-DME-555065 Formation of clathrin coated vesicle IEA Drosophila melanogaster 58189 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 58189 R-DME-5623508 https://reactome.org/PathwayBrowser/#/R-DME-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Drosophila melanogaster 58189 R-DME-5623513 https://reactome.org/PathwayBrowser/#/R-DME-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Drosophila melanogaster 58189 R-DME-5623521 https://reactome.org/PathwayBrowser/#/R-DME-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Drosophila melanogaster 58189 R-DME-5653957 https://reactome.org/PathwayBrowser/#/R-DME-5653957 Rag dimer formation IEA Drosophila melanogaster 58189 R-DME-5653968 https://reactome.org/PathwayBrowser/#/R-DME-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Drosophila melanogaster 58189 R-DME-5653974 https://reactome.org/PathwayBrowser/#/R-DME-5653974 Ragulator binds Rag dimers IEA Drosophila melanogaster 58189 R-DME-5654392 https://reactome.org/PathwayBrowser/#/R-DME-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-5654402 https://reactome.org/PathwayBrowser/#/R-DME-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-5654413 https://reactome.org/PathwayBrowser/#/R-DME-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-5654426 https://reactome.org/PathwayBrowser/#/R-DME-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-5654600 https://reactome.org/PathwayBrowser/#/R-DME-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-5654618 https://reactome.org/PathwayBrowser/#/R-DME-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-5654647 https://reactome.org/PathwayBrowser/#/R-DME-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-5654663 https://reactome.org/PathwayBrowser/#/R-DME-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-5658231 https://reactome.org/PathwayBrowser/#/R-DME-5658231 RAS GAPs stimulate RAS GTPase activity IEA Drosophila melanogaster 58189 R-DME-5672010 https://reactome.org/PathwayBrowser/#/R-DME-5672010 Active MTORC1 phosphorylates ULK1 IEA Drosophila melanogaster 58189 R-DME-5672017 https://reactome.org/PathwayBrowser/#/R-DME-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Drosophila melanogaster 58189 R-DME-5672817 https://reactome.org/PathwayBrowser/#/R-DME-5672817 Active MTORC1 binds the ULK1 complex IEA Drosophila melanogaster 58189 R-DME-5672824 https://reactome.org/PathwayBrowser/#/R-DME-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Drosophila melanogaster 58189 R-DME-5672828 https://reactome.org/PathwayBrowser/#/R-DME-5672828 mTORC1 phosphorylates AKT1S1 IEA Drosophila melanogaster 58189 R-DME-5672843 https://reactome.org/PathwayBrowser/#/R-DME-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Drosophila melanogaster 58189 R-DME-5672965 https://reactome.org/PathwayBrowser/#/R-DME-5672965 RAS GEFs promote RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-5673768 https://reactome.org/PathwayBrowser/#/R-DME-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Drosophila melanogaster 58189 R-DME-5675790 https://reactome.org/PathwayBrowser/#/R-DME-5675790 MTORC1 dissociates from ULK complex IEA Drosophila melanogaster 58189 R-DME-5693925 https://reactome.org/PathwayBrowser/#/R-DME-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Drosophila melanogaster 58189 R-DME-5694409 https://reactome.org/PathwayBrowser/#/R-DME-5694409 Nucleotide exchange on RAB1 IEA Drosophila melanogaster 58189 R-DME-5694439 https://reactome.org/PathwayBrowser/#/R-DME-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Drosophila melanogaster 58189 R-DME-5694527 https://reactome.org/PathwayBrowser/#/R-DME-5694527 Loss of SAR1B GTPase IEA Drosophila melanogaster 58189 R-DME-6788611 https://reactome.org/PathwayBrowser/#/R-DME-6788611 HYKK phosphorylates 5HLYS IEA Drosophila melanogaster 58189 R-DME-6807866 https://reactome.org/PathwayBrowser/#/R-DME-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Drosophila melanogaster 58189 R-DME-6807868 https://reactome.org/PathwayBrowser/#/R-DME-6807868 GBF1 stimulates ARF nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-6807877 https://reactome.org/PathwayBrowser/#/R-DME-6807877 ARFGAPs stimulate ARF GTPase activity IEA Drosophila melanogaster 58189 R-DME-6809003 https://reactome.org/PathwayBrowser/#/R-DME-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Drosophila melanogaster 58189 R-DME-6811411 https://reactome.org/PathwayBrowser/#/R-DME-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Drosophila melanogaster 58189 R-DME-6811414 https://reactome.org/PathwayBrowser/#/R-DME-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Drosophila melanogaster 58189 R-DME-6811418 https://reactome.org/PathwayBrowser/#/R-DME-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Drosophila melanogaster 58189 R-DME-6811426 https://reactome.org/PathwayBrowser/#/R-DME-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Drosophila melanogaster 58189 R-DME-6811427 https://reactome.org/PathwayBrowser/#/R-DME-6811427 COPI vesicle uncoating at the ER IEA Drosophila melanogaster 58189 R-DME-6811428 https://reactome.org/PathwayBrowser/#/R-DME-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Drosophila melanogaster 58189 R-DME-6811429 https://reactome.org/PathwayBrowser/#/R-DME-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-6814682 https://reactome.org/PathwayBrowser/#/R-DME-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Drosophila melanogaster 58189 R-DME-6814833 https://reactome.org/PathwayBrowser/#/R-DME-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Drosophila melanogaster 58189 R-DME-70241 https://reactome.org/PathwayBrowser/#/R-DME-70241 PCK1 phosphorylates OA to yield PEP IEA Drosophila melanogaster 58189 R-DME-71775 https://reactome.org/PathwayBrowser/#/R-DME-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Drosophila melanogaster 58189 R-DME-72670 https://reactome.org/PathwayBrowser/#/R-DME-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Drosophila melanogaster 58189 R-DME-72671 https://reactome.org/PathwayBrowser/#/R-DME-72671 eIF5B:GTP is hydrolyzed and released IEA Drosophila melanogaster 58189 R-DME-72722 https://reactome.org/PathwayBrowser/#/R-DME-72722 eIF2 activation IEA Drosophila melanogaster 58189 R-DME-73788 https://reactome.org/PathwayBrowser/#/R-DME-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Drosophila melanogaster 58189 R-DME-749453 https://reactome.org/PathwayBrowser/#/R-DME-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Drosophila melanogaster 58189 R-DME-751029 https://reactome.org/PathwayBrowser/#/R-DME-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Drosophila melanogaster 58189 R-DME-8847534 https://reactome.org/PathwayBrowser/#/R-DME-8847534 RAB43 hydrolyses GTP IEA Drosophila melanogaster 58189 R-DME-8847883 https://reactome.org/PathwayBrowser/#/R-DME-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Drosophila melanogaster 58189 R-DME-8848618 https://reactome.org/PathwayBrowser/#/R-DME-8848618 Activation of RAC1 by the PXN:CRK complex IEA Drosophila melanogaster 58189 R-DME-8849082 https://reactome.org/PathwayBrowser/#/R-DME-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Drosophila melanogaster 58189 R-DME-8849350 https://reactome.org/PathwayBrowser/#/R-DME-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Drosophila melanogaster 58189 R-DME-8849353 https://reactome.org/PathwayBrowser/#/R-DME-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Drosophila melanogaster 58189 R-DME-8850040 https://reactome.org/PathwayBrowser/#/R-DME-8850040 RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER IEA Drosophila melanogaster 58189 R-DME-8850041 https://reactome.org/PathwayBrowser/#/R-DME-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Drosophila melanogaster 58189 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 58189 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 58189 R-DME-8854173 https://reactome.org/PathwayBrowser/#/R-DME-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Drosophila melanogaster 58189 R-DME-8854255 https://reactome.org/PathwayBrowser/#/R-DME-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 58189 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster 58189 R-DME-8868660 https://reactome.org/PathwayBrowser/#/R-DME-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Drosophila melanogaster 58189 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster 58189 R-DME-8870466 https://reactome.org/PathwayBrowser/#/R-DME-8870466 RGGT:CHM binds RABs IEA Drosophila melanogaster 58189 R-DME-8870469 https://reactome.org/PathwayBrowser/#/R-DME-8870469 RGGT geranylgeranylates RAB proteins IEA Drosophila melanogaster 58189 R-DME-8871194 https://reactome.org/PathwayBrowser/#/R-DME-8871194 RAB5 and GAPVD1 bind AP-2 IEA Drosophila melanogaster 58189 R-DME-8875318 https://reactome.org/PathwayBrowser/#/R-DME-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Drosophila melanogaster 58189 R-DME-8875320 https://reactome.org/PathwayBrowser/#/R-DME-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Drosophila melanogaster 58189 R-DME-8876188 https://reactome.org/PathwayBrowser/#/R-DME-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Drosophila melanogaster 58189 R-DME-8876193 https://reactome.org/PathwayBrowser/#/R-DME-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Drosophila melanogaster 58189 R-DME-8876615 https://reactome.org/PathwayBrowser/#/R-DME-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Drosophila melanogaster 58189 R-DME-8876616 https://reactome.org/PathwayBrowser/#/R-DME-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Drosophila melanogaster 58189 R-DME-8876837 https://reactome.org/PathwayBrowser/#/R-DME-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Drosophila melanogaster 58189 R-DME-8877308 https://reactome.org/PathwayBrowser/#/R-DME-8877308 MADD exchanges GTP for GDP on RAB27 IEA Drosophila melanogaster 58189 R-DME-8877451 https://reactome.org/PathwayBrowser/#/R-DME-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Drosophila melanogaster 58189 R-DME-8877475 https://reactome.org/PathwayBrowser/#/R-DME-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Drosophila melanogaster 58189 R-DME-8877612 https://reactome.org/PathwayBrowser/#/R-DME-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Drosophila melanogaster 58189 R-DME-8877760 https://reactome.org/PathwayBrowser/#/R-DME-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Drosophila melanogaster 58189 R-DME-8877813 https://reactome.org/PathwayBrowser/#/R-DME-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Drosophila melanogaster 58189 R-DME-8877998 https://reactome.org/PathwayBrowser/#/R-DME-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Drosophila melanogaster 58189 R-DME-8941613 https://reactome.org/PathwayBrowser/#/R-DME-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-8941618 https://reactome.org/PathwayBrowser/#/R-DME-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-8941623 https://reactome.org/PathwayBrowser/#/R-DME-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-8941628 https://reactome.org/PathwayBrowser/#/R-DME-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Drosophila melanogaster 58189 R-DME-8944454 https://reactome.org/PathwayBrowser/#/R-DME-8944454 mTORC1 phosphorylates MAF1 IEA Drosophila melanogaster 58189 R-DME-8944457 https://reactome.org/PathwayBrowser/#/R-DME-8944457 MAF1 translocates to the nucleus IEA Drosophila melanogaster 58189 R-DME-8951586 https://reactome.org/PathwayBrowser/#/R-DME-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Drosophila melanogaster 58189 R-DME-8952726 https://reactome.org/PathwayBrowser/#/R-DME-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Drosophila melanogaster 58189 R-DME-8980691 https://reactome.org/PathwayBrowser/#/R-DME-8980691 RHOA GEFs activate RHOA IEA Drosophila melanogaster 58189 R-DME-8981353 https://reactome.org/PathwayBrowser/#/R-DME-8981353 RASA1 stimulates RAS GTPase activity IEA Drosophila melanogaster 58189 R-DME-8981637 https://reactome.org/PathwayBrowser/#/R-DME-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Drosophila melanogaster 58189 R-DME-8982012 https://reactome.org/PathwayBrowser/#/R-DME-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Drosophila melanogaster 58189 R-DME-8982020 https://reactome.org/PathwayBrowser/#/R-DME-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Drosophila melanogaster 58189 R-DME-8982025 https://reactome.org/PathwayBrowser/#/R-DME-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Drosophila melanogaster 58189 R-DME-8982026 https://reactome.org/PathwayBrowser/#/R-DME-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Drosophila melanogaster 58189 R-DME-9012835 https://reactome.org/PathwayBrowser/#/R-DME-9012835 GDIs block activation of RHOA IEA Drosophila melanogaster 58189 R-DME-9013021 https://reactome.org/PathwayBrowser/#/R-DME-9013021 GDIs block activation of RHOB IEA Drosophila melanogaster 58189 R-DME-9013022 https://reactome.org/PathwayBrowser/#/R-DME-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Drosophila melanogaster 58189 R-DME-9013023 https://reactome.org/PathwayBrowser/#/R-DME-9013023 RHOB GEFs activate RHOB IEA Drosophila melanogaster 58189 R-DME-9013143 https://reactome.org/PathwayBrowser/#/R-DME-9013143 RAC1 GEFs activate RAC1 IEA Drosophila melanogaster 58189 R-DME-9013144 https://reactome.org/PathwayBrowser/#/R-DME-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Drosophila melanogaster 58189 R-DME-9013147 https://reactome.org/PathwayBrowser/#/R-DME-9013147 RAC1 GDIs block activation of RAC1 IEA Drosophila melanogaster 58189 R-DME-9013158 https://reactome.org/PathwayBrowser/#/R-DME-9013158 CDC42 GDIs block activation of CDC42 IEA Drosophila melanogaster 58189 R-DME-9013159 https://reactome.org/PathwayBrowser/#/R-DME-9013159 CDC42 GEFs activate CDC42 IEA Drosophila melanogaster 58189 R-DME-9013161 https://reactome.org/PathwayBrowser/#/R-DME-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Drosophila melanogaster 58189 R-DME-9013435 https://reactome.org/PathwayBrowser/#/R-DME-9013435 RHOD auto-activates IEA Drosophila melanogaster 58189 R-DME-9013437 https://reactome.org/PathwayBrowser/#/R-DME-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Drosophila melanogaster 58189 R-DME-9014293 https://reactome.org/PathwayBrowser/#/R-DME-9014293 RAC2 GDIs block activation of RAC2 IEA Drosophila melanogaster 58189 R-DME-9014295 https://reactome.org/PathwayBrowser/#/R-DME-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Drosophila melanogaster 58189 R-DME-9014296 https://reactome.org/PathwayBrowser/#/R-DME-9014296 RAC2 GEFs activate RAC2 IEA Drosophila melanogaster 58189 R-DME-9014433 https://reactome.org/PathwayBrowser/#/R-DME-9014433 RHOG GEFs activate RHOG IEA Drosophila melanogaster 58189 R-DME-9014434 https://reactome.org/PathwayBrowser/#/R-DME-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Drosophila melanogaster 58189 R-DME-9014456 https://reactome.org/PathwayBrowser/#/R-DME-9014456 GDIs block activation of RHOG IEA Drosophila melanogaster 58189 R-DME-9017488 https://reactome.org/PathwayBrowser/#/R-DME-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Drosophila melanogaster 58189 R-DME-9017491 https://reactome.org/PathwayBrowser/#/R-DME-9017491 RHOJ GEFs activate RHOJ IEA Drosophila melanogaster 58189 R-DME-9018745 https://reactome.org/PathwayBrowser/#/R-DME-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Drosophila melanogaster 58189 R-DME-9018747 https://reactome.org/PathwayBrowser/#/R-DME-9018747 RHOQ GEFs activate RHOQ IEA Drosophila melanogaster 58189 R-DME-9018768 https://reactome.org/PathwayBrowser/#/R-DME-9018768 RHOU auto-activates IEA Drosophila melanogaster 58189 R-DME-9018798 https://reactome.org/PathwayBrowser/#/R-DME-9018798 RHOV binds GTP IEA Drosophila melanogaster 58189 R-DME-9018804 https://reactome.org/PathwayBrowser/#/R-DME-9018804 RAC3 GEFs activate RAC3 IEA Drosophila melanogaster 58189 R-DME-9018806 https://reactome.org/PathwayBrowser/#/R-DME-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Drosophila melanogaster 58189 R-DME-9018807 https://reactome.org/PathwayBrowser/#/R-DME-9018807 RAC3 GDIs block activation of RAC3 IEA Drosophila melanogaster 58189 R-DME-9018814 https://reactome.org/PathwayBrowser/#/R-DME-9018814 RHOT1 hydrolyzes GTP IEA Drosophila melanogaster 58189 R-DME-9018826 https://reactome.org/PathwayBrowser/#/R-DME-9018826 RHOT2 hydrolyzes GTP IEA Drosophila melanogaster 58189 R-DME-927789 https://reactome.org/PathwayBrowser/#/R-DME-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Drosophila melanogaster 58189 R-DME-927832 https://reactome.org/PathwayBrowser/#/R-DME-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Drosophila melanogaster 58189 R-DME-927836 https://reactome.org/PathwayBrowser/#/R-DME-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Drosophila melanogaster 58189 R-DME-927889 https://reactome.org/PathwayBrowser/#/R-DME-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Drosophila melanogaster 58189 R-DME-939265 https://reactome.org/PathwayBrowser/#/R-DME-939265 Activation of Rap1 by membrane-associated GEFs IEA Drosophila melanogaster 58189 R-DME-9603984 https://reactome.org/PathwayBrowser/#/R-DME-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Drosophila melanogaster 58189 R-DME-9603986 https://reactome.org/PathwayBrowser/#/R-DME-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Drosophila melanogaster 58189 R-DME-9605609 https://reactome.org/PathwayBrowser/#/R-DME-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Drosophila melanogaster 58189 R-DME-9605644 https://reactome.org/PathwayBrowser/#/R-DME-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Drosophila melanogaster 58189 R-DME-9605682 https://reactome.org/PathwayBrowser/#/R-DME-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Drosophila melanogaster 58189 R-DME-9607304 https://reactome.org/PathwayBrowser/#/R-DME-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Drosophila melanogaster 58189 R-DME-9624845 https://reactome.org/PathwayBrowser/#/R-DME-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Drosophila melanogaster 58189 R-DME-9624893 https://reactome.org/PathwayBrowser/#/R-DME-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Drosophila melanogaster 58189 R-DME-9632906 https://reactome.org/PathwayBrowser/#/R-DME-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Drosophila melanogaster 58189 R-DME-9632918 https://reactome.org/PathwayBrowser/#/R-DME-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Drosophila melanogaster 58189 R-DME-9639286 https://reactome.org/PathwayBrowser/#/R-DME-9639286 RRAGC,D exchanges GTP for GDP IEA Drosophila melanogaster 58189 R-DME-9640167 https://reactome.org/PathwayBrowser/#/R-DME-9640167 RRAGA,B exchanges GDP for GTP IEA Drosophila melanogaster 58189 R-DME-9640195 https://reactome.org/PathwayBrowser/#/R-DME-9640195 RRAGA,B hydrolyzes GTP IEA Drosophila melanogaster 58189 R-DME-9645598 https://reactome.org/PathwayBrowser/#/R-DME-9645598 RRAGC,D hydrolyzes GTP IEA Drosophila melanogaster 58189 R-DME-9645608 https://reactome.org/PathwayBrowser/#/R-DME-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Drosophila melanogaster 58189 R-DME-9646468 https://reactome.org/PathwayBrowser/#/R-DME-9646468 mTORC1 binds RHEB:GTP IEA Drosophila melanogaster 58189 R-DME-9649733 https://reactome.org/PathwayBrowser/#/R-DME-9649733 mature p21 RAS binds GDP IEA Drosophila melanogaster 58189 R-DME-9649735 https://reactome.org/PathwayBrowser/#/R-DME-9649735 Intrinsic nucleotide exchange on RAS IEA Drosophila melanogaster 58189 R-DME-9649736 https://reactome.org/PathwayBrowser/#/R-DME-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Drosophila melanogaster 58189 R-DME-9693111 https://reactome.org/PathwayBrowser/#/R-DME-9693111 RHOF auto-activates IEA Drosophila melanogaster 58189 R-DME-9693282 https://reactome.org/PathwayBrowser/#/R-DME-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Drosophila melanogaster 58189 R-DME-9693775 https://reactome.org/PathwayBrowser/#/R-DME-9693775 Vimar activates Miro TAS Drosophila melanogaster 58189 R-DME-9726862 https://reactome.org/PathwayBrowser/#/R-DME-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Drosophila melanogaster 58189 R-DME-9751201 https://reactome.org/PathwayBrowser/#/R-DME-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Drosophila melanogaster 58189 R-DME-983259 https://reactome.org/PathwayBrowser/#/R-DME-983259 Kinesins move along microtubules consuming ATP IEA Drosophila melanogaster 58189 R-DRE-1028788 https://reactome.org/PathwayBrowser/#/R-DRE-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Danio rerio 58189 R-DRE-110133 https://reactome.org/PathwayBrowser/#/R-DRE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Danio rerio 58189 R-DRE-111524 https://reactome.org/PathwayBrowser/#/R-DRE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Danio rerio 58189 R-DRE-114552 https://reactome.org/PathwayBrowser/#/R-DRE-114552 Thrombin-activated PARs activate G12/13 IEA Danio rerio 58189 R-DRE-114558 https://reactome.org/PathwayBrowser/#/R-DRE-114558 Thrombin-activated PARs activate Gq IEA Danio rerio 58189 R-DRE-1168636 https://reactome.org/PathwayBrowser/#/R-DRE-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Danio rerio 58189 R-DRE-1250383 https://reactome.org/PathwayBrowser/#/R-DRE-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Danio rerio 58189 R-DRE-1306972 https://reactome.org/PathwayBrowser/#/R-DRE-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Danio rerio 58189 R-DRE-1433471 https://reactome.org/PathwayBrowser/#/R-DRE-1433471 Activation of RAS by p-KIT bound SOS1 IEA Danio rerio 58189 R-DRE-162721 https://reactome.org/PathwayBrowser/#/R-DRE-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Danio rerio 58189 R-DRE-165195 https://reactome.org/PathwayBrowser/#/R-DRE-165195 GTP loading by Rheb IEA Danio rerio 58189 R-DRE-165680 https://reactome.org/PathwayBrowser/#/R-DRE-165680 Formation of active mTORC1 complex IEA Danio rerio 58189 R-DRE-165692 https://reactome.org/PathwayBrowser/#/R-DRE-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Danio rerio 58189 R-DRE-165718 https://reactome.org/PathwayBrowser/#/R-DRE-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Danio rerio 58189 R-DRE-167415 https://reactome.org/PathwayBrowser/#/R-DRE-167415 G-protein alpha subunit is inactivated IEA Danio rerio 58189 R-DRE-169904 https://reactome.org/PathwayBrowser/#/R-DRE-169904 C3G stimulates nucleotide exchange on Rap1 IEA Danio rerio 58189 R-DRE-170026 https://reactome.org/PathwayBrowser/#/R-DRE-170026 Protons are translocated from the intermembrane space to the matrix IEA Danio rerio 58189 R-DRE-170666 https://reactome.org/PathwayBrowser/#/R-DRE-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Danio rerio 58189 R-DRE-170674 https://reactome.org/PathwayBrowser/#/R-DRE-170674 Dissociation of the Gi alpha:G olf complex IEA Danio rerio 58189 R-DRE-170677 https://reactome.org/PathwayBrowser/#/R-DRE-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Danio rerio 58189 R-DRE-170685 https://reactome.org/PathwayBrowser/#/R-DRE-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Danio rerio 58189 R-DRE-170686 https://reactome.org/PathwayBrowser/#/R-DRE-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Danio rerio 58189 R-DRE-177938 https://reactome.org/PathwayBrowser/#/R-DRE-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Danio rerio 58189 R-DRE-177945 https://reactome.org/PathwayBrowser/#/R-DRE-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Danio rerio 58189 R-DRE-186834 https://reactome.org/PathwayBrowser/#/R-DRE-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Danio rerio 58189 R-DRE-193646 https://reactome.org/PathwayBrowser/#/R-DRE-193646 NGF binding to p75NTR inactivates RHOA IEA Danio rerio 58189 R-DRE-193668 https://reactome.org/PathwayBrowser/#/R-DRE-193668 p75NTR and RHOA-GDI interact IEA Danio rerio 58189 R-DRE-193696 https://reactome.org/PathwayBrowser/#/R-DRE-193696 The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA IEA Danio rerio 58189 R-DRE-203977 https://reactome.org/PathwayBrowser/#/R-DRE-203977 SAR1 Activation And Membrane Binding IEA Danio rerio 58189 R-DRE-205039 https://reactome.org/PathwayBrowser/#/R-DRE-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Danio rerio 58189 R-DRE-210977 https://reactome.org/PathwayBrowser/#/R-DRE-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Danio rerio 58189 R-DRE-2130641 https://reactome.org/PathwayBrowser/#/R-DRE-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Danio rerio 58189 R-DRE-2179407 https://reactome.org/PathwayBrowser/#/R-DRE-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Danio rerio 58189 R-DRE-372819 https://reactome.org/PathwayBrowser/#/R-DRE-372819 PCK2 phosphorylates OA to yield PEP IEA Danio rerio 58189 R-DRE-377186 https://reactome.org/PathwayBrowser/#/R-DRE-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Danio rerio 58189 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 58189 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 58189 R-DRE-380979 https://reactome.org/PathwayBrowser/#/R-DRE-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Danio rerio 58189 R-DRE-381727 https://reactome.org/PathwayBrowser/#/R-DRE-381727 RAP1A exchanges GDP for GTP IEA Danio rerio 58189 R-DRE-392195 https://reactome.org/PathwayBrowser/#/R-DRE-392195 Gi activation by P2Y purinoceptor 12 IEA Danio rerio 58189 R-DRE-392513 https://reactome.org/PathwayBrowser/#/R-DRE-392513 Rap1 signal termination by Rap1GAPs IEA Danio rerio 58189 R-DRE-3928628 https://reactome.org/PathwayBrowser/#/R-DRE-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Danio rerio 58189 R-DRE-3928642 https://reactome.org/PathwayBrowser/#/R-DRE-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Danio rerio 58189 R-DRE-3928651 https://reactome.org/PathwayBrowser/#/R-DRE-3928651 NGEF exchanges GTP for GDP on RHOA IEA Danio rerio 58189 R-DRE-400092 https://reactome.org/PathwayBrowser/#/R-DRE-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Danio rerio 58189 R-DRE-4093339 https://reactome.org/PathwayBrowser/#/R-DRE-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Danio rerio 58189 R-DRE-416559 https://reactome.org/PathwayBrowser/#/R-DRE-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Danio rerio 58189 R-DRE-416588 https://reactome.org/PathwayBrowser/#/R-DRE-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Danio rerio 58189 R-DRE-418850 https://reactome.org/PathwayBrowser/#/R-DRE-418850 Activation of Cdc42 IEA Danio rerio 58189 R-DRE-418856 https://reactome.org/PathwayBrowser/#/R-DRE-418856 Activation of Rac1 IEA Danio rerio 58189 R-DRE-419166 https://reactome.org/PathwayBrowser/#/R-DRE-419166 GEFs activate RhoA,B,C IEA Danio rerio 58189 R-DRE-420883 https://reactome.org/PathwayBrowser/#/R-DRE-420883 Opsins act as GEFs for G alpha-t IEA Danio rerio 58189 R-DRE-428750 https://reactome.org/PathwayBrowser/#/R-DRE-428750 Gq activation by TP receptor IEA Danio rerio 58189 R-DRE-428917 https://reactome.org/PathwayBrowser/#/R-DRE-428917 G13 activation by TP receptor IEA Danio rerio 58189 R-DRE-432195 https://reactome.org/PathwayBrowser/#/R-DRE-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Danio rerio 58189 R-DRE-432707 https://reactome.org/PathwayBrowser/#/R-DRE-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Danio rerio 58189 R-DRE-446218 https://reactome.org/PathwayBrowser/#/R-DRE-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Danio rerio 58189 R-DRE-447074 https://reactome.org/PathwayBrowser/#/R-DRE-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Danio rerio 58189 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 58189 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 58189 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 58189 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 58189 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 58189 R-DRE-5623513 https://reactome.org/PathwayBrowser/#/R-DRE-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Danio rerio 58189 R-DRE-5623519 https://reactome.org/PathwayBrowser/#/R-DRE-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Danio rerio 58189 R-DRE-5623521 https://reactome.org/PathwayBrowser/#/R-DRE-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Danio rerio 58189 R-DRE-5653957 https://reactome.org/PathwayBrowser/#/R-DRE-5653957 Rag dimer formation IEA Danio rerio 58189 R-DRE-5653968 https://reactome.org/PathwayBrowser/#/R-DRE-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Danio rerio 58189 R-DRE-5653974 https://reactome.org/PathwayBrowser/#/R-DRE-5653974 Ragulator binds Rag dimers IEA Danio rerio 58189 R-DRE-5654392 https://reactome.org/PathwayBrowser/#/R-DRE-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 58189 R-DRE-5654402 https://reactome.org/PathwayBrowser/#/R-DRE-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 58189 R-DRE-5654413 https://reactome.org/PathwayBrowser/#/R-DRE-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 58189 R-DRE-5654600 https://reactome.org/PathwayBrowser/#/R-DRE-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 58189 R-DRE-5654618 https://reactome.org/PathwayBrowser/#/R-DRE-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 58189 R-DRE-5654647 https://reactome.org/PathwayBrowser/#/R-DRE-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 58189 R-DRE-5654663 https://reactome.org/PathwayBrowser/#/R-DRE-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Danio rerio 58189 R-DRE-5665809 https://reactome.org/PathwayBrowser/#/R-DRE-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Danio rerio 58189 R-DRE-5672010 https://reactome.org/PathwayBrowser/#/R-DRE-5672010 Active MTORC1 phosphorylates ULK1 IEA Danio rerio 58189 R-DRE-5672017 https://reactome.org/PathwayBrowser/#/R-DRE-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Danio rerio 58189 R-DRE-5672824 https://reactome.org/PathwayBrowser/#/R-DRE-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Danio rerio 58189 R-DRE-5672828 https://reactome.org/PathwayBrowser/#/R-DRE-5672828 mTORC1 phosphorylates AKT1S1 IEA Danio rerio 58189 R-DRE-5672965 https://reactome.org/PathwayBrowser/#/R-DRE-5672965 RAS GEFs promote RAS nucleotide exchange IEA Danio rerio 58189 R-DRE-5673768 https://reactome.org/PathwayBrowser/#/R-DRE-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Danio rerio 58189 R-DRE-5694409 https://reactome.org/PathwayBrowser/#/R-DRE-5694409 Nucleotide exchange on RAB1 IEA Danio rerio 58189 R-DRE-6788611 https://reactome.org/PathwayBrowser/#/R-DRE-6788611 HYKK phosphorylates 5HLYS IEA Danio rerio 58189 R-DRE-6807868 https://reactome.org/PathwayBrowser/#/R-DRE-6807868 GBF1 stimulates ARF nucleotide exchange IEA Danio rerio 58189 R-DRE-6811427 https://reactome.org/PathwayBrowser/#/R-DRE-6811427 COPI vesicle uncoating at the ER IEA Danio rerio 58189 R-DRE-6814833 https://reactome.org/PathwayBrowser/#/R-DRE-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Danio rerio 58189 R-DRE-70241 https://reactome.org/PathwayBrowser/#/R-DRE-70241 PCK1 phosphorylates OA to yield PEP IEA Danio rerio 58189 R-DRE-72670 https://reactome.org/PathwayBrowser/#/R-DRE-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Danio rerio 58189 R-DRE-72722 https://reactome.org/PathwayBrowser/#/R-DRE-72722 eIF2 activation IEA Danio rerio 58189 R-DRE-73788 https://reactome.org/PathwayBrowser/#/R-DRE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Danio rerio 58189 R-DRE-751029 https://reactome.org/PathwayBrowser/#/R-DRE-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Danio rerio 58189 R-DRE-8848618 https://reactome.org/PathwayBrowser/#/R-DRE-8848618 Activation of RAC1 by the PXN:CRK complex IEA Danio rerio 58189 R-DRE-8849082 https://reactome.org/PathwayBrowser/#/R-DRE-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Danio rerio 58189 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 58189 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 58189 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 58189 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 58189 R-DRE-8851827 https://reactome.org/PathwayBrowser/#/R-DRE-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Danio rerio 58189 R-DRE-8851877 https://reactome.org/PathwayBrowser/#/R-DRE-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Danio rerio 58189 R-DRE-8854173 https://reactome.org/PathwayBrowser/#/R-DRE-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Danio rerio 58189 R-DRE-8854255 https://reactome.org/PathwayBrowser/#/R-DRE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Danio rerio 58189 R-DRE-8854612 https://reactome.org/PathwayBrowser/#/R-DRE-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Danio rerio 58189 R-DRE-8870466 https://reactome.org/PathwayBrowser/#/R-DRE-8870466 RGGT:CHM binds RABs IEA Danio rerio 58189 R-DRE-8870469 https://reactome.org/PathwayBrowser/#/R-DRE-8870469 RGGT geranylgeranylates RAB proteins IEA Danio rerio 58189 R-DRE-8875320 https://reactome.org/PathwayBrowser/#/R-DRE-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Danio rerio 58189 R-DRE-8876190 https://reactome.org/PathwayBrowser/#/R-DRE-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Danio rerio 58189 R-DRE-8876616 https://reactome.org/PathwayBrowser/#/R-DRE-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Danio rerio 58189 R-DRE-8877760 https://reactome.org/PathwayBrowser/#/R-DRE-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Danio rerio 58189 R-DRE-8938815 https://reactome.org/PathwayBrowser/#/R-DRE-8938815 RNF152 polyubiquitinates RRAGA IEA Danio rerio 58189 R-DRE-8938829 https://reactome.org/PathwayBrowser/#/R-DRE-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 IEA Danio rerio 58189 R-DRE-8941618 https://reactome.org/PathwayBrowser/#/R-DRE-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Danio rerio 58189 R-DRE-8941623 https://reactome.org/PathwayBrowser/#/R-DRE-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Danio rerio 58189 R-DRE-8941628 https://reactome.org/PathwayBrowser/#/R-DRE-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Danio rerio 58189 R-DRE-8944454 https://reactome.org/PathwayBrowser/#/R-DRE-8944454 mTORC1 phosphorylates MAF1 IEA Danio rerio 58189 R-DRE-8944457 https://reactome.org/PathwayBrowser/#/R-DRE-8944457 MAF1 translocates to the nucleus IEA Danio rerio 58189 R-DRE-8951498 https://reactome.org/PathwayBrowser/#/R-DRE-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Danio rerio 58189 R-DRE-8952716 https://reactome.org/PathwayBrowser/#/R-DRE-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Danio rerio 58189 R-DRE-8952726 https://reactome.org/PathwayBrowser/#/R-DRE-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Danio rerio 58189 R-DRE-8980691 https://reactome.org/PathwayBrowser/#/R-DRE-8980691 RHOA GEFs activate RHOA IEA Danio rerio 58189 R-DRE-8981353 https://reactome.org/PathwayBrowser/#/R-DRE-8981353 RASA1 stimulates RAS GTPase activity IEA Danio rerio 58189 R-DRE-8981637 https://reactome.org/PathwayBrowser/#/R-DRE-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Danio rerio 58189 R-DRE-8982012 https://reactome.org/PathwayBrowser/#/R-DRE-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Danio rerio 58189 R-DRE-8982020 https://reactome.org/PathwayBrowser/#/R-DRE-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Danio rerio 58189 R-DRE-8982025 https://reactome.org/PathwayBrowser/#/R-DRE-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Danio rerio 58189 R-DRE-8982026 https://reactome.org/PathwayBrowser/#/R-DRE-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Danio rerio 58189 R-DRE-9012761 https://reactome.org/PathwayBrowser/#/R-DRE-9012761 The p75NTR:NgR:MDGI binds RHOA-GDI IEA Danio rerio 58189 R-DRE-9012835 https://reactome.org/PathwayBrowser/#/R-DRE-9012835 GDIs block activation of RHOA IEA Danio rerio 58189 R-DRE-9013143 https://reactome.org/PathwayBrowser/#/R-DRE-9013143 RAC1 GEFs activate RAC1 IEA Danio rerio 58189 R-DRE-9013144 https://reactome.org/PathwayBrowser/#/R-DRE-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Danio rerio 58189 R-DRE-9013147 https://reactome.org/PathwayBrowser/#/R-DRE-9013147 RAC1 GDIs block activation of RAC1 IEA Danio rerio 58189 R-DRE-9013158 https://reactome.org/PathwayBrowser/#/R-DRE-9013158 CDC42 GDIs block activation of CDC42 IEA Danio rerio 58189 R-DRE-9013159 https://reactome.org/PathwayBrowser/#/R-DRE-9013159 CDC42 GEFs activate CDC42 IEA Danio rerio 58189 R-DRE-9013161 https://reactome.org/PathwayBrowser/#/R-DRE-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Danio rerio 58189 R-DRE-9013435 https://reactome.org/PathwayBrowser/#/R-DRE-9013435 RHOD auto-activates IEA Danio rerio 58189 R-DRE-9013437 https://reactome.org/PathwayBrowser/#/R-DRE-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Danio rerio 58189 R-DRE-9014293 https://reactome.org/PathwayBrowser/#/R-DRE-9014293 RAC2 GDIs block activation of RAC2 IEA Danio rerio 58189 R-DRE-9014295 https://reactome.org/PathwayBrowser/#/R-DRE-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Danio rerio 58189 R-DRE-9014296 https://reactome.org/PathwayBrowser/#/R-DRE-9014296 RAC2 GEFs activate RAC2 IEA Danio rerio 58189 R-DRE-9014433 https://reactome.org/PathwayBrowser/#/R-DRE-9014433 RHOG GEFs activate RHOG IEA Danio rerio 58189 R-DRE-9014434 https://reactome.org/PathwayBrowser/#/R-DRE-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Danio rerio 58189 R-DRE-9014456 https://reactome.org/PathwayBrowser/#/R-DRE-9014456 GDIs block activation of RHOG IEA Danio rerio 58189 R-DRE-9018745 https://reactome.org/PathwayBrowser/#/R-DRE-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Danio rerio 58189 R-DRE-9018768 https://reactome.org/PathwayBrowser/#/R-DRE-9018768 RHOU auto-activates IEA Danio rerio 58189 R-DRE-9018798 https://reactome.org/PathwayBrowser/#/R-DRE-9018798 RHOV binds GTP IEA Danio rerio 58189 R-DRE-9018804 https://reactome.org/PathwayBrowser/#/R-DRE-9018804 RAC3 GEFs activate RAC3 IEA Danio rerio 58189 R-DRE-9018806 https://reactome.org/PathwayBrowser/#/R-DRE-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Danio rerio 58189 R-DRE-9018807 https://reactome.org/PathwayBrowser/#/R-DRE-9018807 RAC3 GDIs block activation of RAC3 IEA Danio rerio 58189 R-DRE-9018814 https://reactome.org/PathwayBrowser/#/R-DRE-9018814 RHOT1 hydrolyzes GTP IEA Danio rerio 58189 R-DRE-9018826 https://reactome.org/PathwayBrowser/#/R-DRE-9018826 RHOT2 hydrolyzes GTP IEA Danio rerio 58189 R-DRE-927789 https://reactome.org/PathwayBrowser/#/R-DRE-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Danio rerio 58189 R-DRE-927813 https://reactome.org/PathwayBrowser/#/R-DRE-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Danio rerio 58189 R-DRE-927836 https://reactome.org/PathwayBrowser/#/R-DRE-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Danio rerio 58189 R-DRE-927889 https://reactome.org/PathwayBrowser/#/R-DRE-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Danio rerio 58189 R-DRE-9603984 https://reactome.org/PathwayBrowser/#/R-DRE-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Danio rerio 58189 R-DRE-9605682 https://reactome.org/PathwayBrowser/#/R-DRE-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Danio rerio 58189 R-DRE-9624845 https://reactome.org/PathwayBrowser/#/R-DRE-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Danio rerio 58189 R-DRE-9624893 https://reactome.org/PathwayBrowser/#/R-DRE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Danio rerio 58189 R-DRE-9639286 https://reactome.org/PathwayBrowser/#/R-DRE-9639286 RRAGC,D exchanges GTP for GDP IEA Danio rerio 58189 R-DRE-9640167 https://reactome.org/PathwayBrowser/#/R-DRE-9640167 RRAGA,B exchanges GDP for GTP IEA Danio rerio 58189 R-DRE-9640168 https://reactome.org/PathwayBrowser/#/R-DRE-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Danio rerio 58189 R-DRE-9640175 https://reactome.org/PathwayBrowser/#/R-DRE-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Danio rerio 58189 R-DRE-9640195 https://reactome.org/PathwayBrowser/#/R-DRE-9640195 RRAGA,B hydrolyzes GTP IEA Danio rerio 58189 R-DRE-9645598 https://reactome.org/PathwayBrowser/#/R-DRE-9645598 RRAGC,D hydrolyzes GTP IEA Danio rerio 58189 R-DRE-9645608 https://reactome.org/PathwayBrowser/#/R-DRE-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Danio rerio 58189 R-DRE-9646468 https://reactome.org/PathwayBrowser/#/R-DRE-9646468 mTORC1 binds RHEB:GTP IEA Danio rerio 58189 R-DRE-9646679 https://reactome.org/PathwayBrowser/#/R-DRE-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Danio rerio 58189 R-DRE-9649733 https://reactome.org/PathwayBrowser/#/R-DRE-9649733 mature p21 RAS binds GDP IEA Danio rerio 58189 R-DRE-9649735 https://reactome.org/PathwayBrowser/#/R-DRE-9649735 Intrinsic nucleotide exchange on RAS IEA Danio rerio 58189 R-DRE-9649736 https://reactome.org/PathwayBrowser/#/R-DRE-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Danio rerio 58189 R-DRE-9693111 https://reactome.org/PathwayBrowser/#/R-DRE-9693111 RHOF auto-activates IEA Danio rerio 58189 R-DRE-9693282 https://reactome.org/PathwayBrowser/#/R-DRE-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Danio rerio 58189 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 58189 R-DRE-9717206 https://reactome.org/PathwayBrowser/#/R-DRE-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Danio rerio 58189 R-DRE-9726862 https://reactome.org/PathwayBrowser/#/R-DRE-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Danio rerio 58189 R-DRE-9728664 https://reactome.org/PathwayBrowser/#/R-DRE-9728664 GLP1R binds GLP1R agonists IEA Danio rerio 58189 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 58189 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 58189 R-GGA-1008248 https://reactome.org/PathwayBrowser/#/R-GGA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Gallus gallus 58189 R-GGA-1028788 https://reactome.org/PathwayBrowser/#/R-GGA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Gallus gallus 58189 R-GGA-110133 https://reactome.org/PathwayBrowser/#/R-GGA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Gallus gallus 58189 R-GGA-111524 https://reactome.org/PathwayBrowser/#/R-GGA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Gallus gallus 58189 R-GGA-112037 https://reactome.org/PathwayBrowser/#/R-GGA-112037 Inactivation of PLC beta IEA Gallus gallus 58189 R-GGA-114552 https://reactome.org/PathwayBrowser/#/R-GGA-114552 Thrombin-activated PARs activate G12/13 IEA Gallus gallus 58189 R-GGA-114558 https://reactome.org/PathwayBrowser/#/R-GGA-114558 Thrombin-activated PARs activate Gq IEA Gallus gallus 58189 R-GGA-1168636 https://reactome.org/PathwayBrowser/#/R-GGA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Gallus gallus 58189 R-GGA-1250383 https://reactome.org/PathwayBrowser/#/R-GGA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Gallus gallus 58189 R-GGA-1306972 https://reactome.org/PathwayBrowser/#/R-GGA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Gallus gallus 58189 R-GGA-1433471 https://reactome.org/PathwayBrowser/#/R-GGA-1433471 Activation of RAS by p-KIT bound SOS1 IEA Gallus gallus 58189 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus 58189 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus 58189 R-GGA-165195 https://reactome.org/PathwayBrowser/#/R-GGA-165195 GTP loading by Rheb IEA Gallus gallus 58189 R-GGA-165680 https://reactome.org/PathwayBrowser/#/R-GGA-165680 Formation of active mTORC1 complex IEA Gallus gallus 58189 R-GGA-165692 https://reactome.org/PathwayBrowser/#/R-GGA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Gallus gallus 58189 R-GGA-165718 https://reactome.org/PathwayBrowser/#/R-GGA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Gallus gallus 58189 R-GGA-167408 https://reactome.org/PathwayBrowser/#/R-GGA-167408 The high affinity receptor complex binds to G-protein IEA Gallus gallus 58189 R-GGA-167415 https://reactome.org/PathwayBrowser/#/R-GGA-167415 G-protein alpha subunit is inactivated IEA Gallus gallus 58189 R-GGA-167419 https://reactome.org/PathwayBrowser/#/R-GGA-167419 The receptor:G-protein complex releases GDP IEA Gallus gallus 58189 R-GGA-167433 https://reactome.org/PathwayBrowser/#/R-GGA-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Gallus gallus 58189 R-GGA-169904 https://reactome.org/PathwayBrowser/#/R-GGA-169904 C3G stimulates nucleotide exchange on Rap1 IEA Gallus gallus 58189 R-GGA-170026 https://reactome.org/PathwayBrowser/#/R-GGA-170026 Protons are translocated from the intermembrane space to the matrix IEA Gallus gallus 58189 R-GGA-170666 https://reactome.org/PathwayBrowser/#/R-GGA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus 58189 R-GGA-170674 https://reactome.org/PathwayBrowser/#/R-GGA-170674 Dissociation of the Gi alpha:G olf complex IEA Gallus gallus 58189 R-GGA-170677 https://reactome.org/PathwayBrowser/#/R-GGA-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Gallus gallus 58189 R-GGA-170685 https://reactome.org/PathwayBrowser/#/R-GGA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus 58189 R-GGA-170686 https://reactome.org/PathwayBrowser/#/R-GGA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Gallus gallus 58189 R-GGA-177938 https://reactome.org/PathwayBrowser/#/R-GGA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Gallus gallus 58189 R-GGA-177945 https://reactome.org/PathwayBrowser/#/R-GGA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Gallus gallus 58189 R-GGA-186834 https://reactome.org/PathwayBrowser/#/R-GGA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Gallus gallus 58189 R-GGA-193646 https://reactome.org/PathwayBrowser/#/R-GGA-193646 NGF binding to p75NTR inactivates RHOA IEA Gallus gallus 58189 R-GGA-193668 https://reactome.org/PathwayBrowser/#/R-GGA-193668 p75NTR and RHOA-GDI interact IEA Gallus gallus 58189 R-GGA-194518 https://reactome.org/PathwayBrowser/#/R-GGA-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Gallus gallus 58189 R-GGA-2029451 https://reactome.org/PathwayBrowser/#/R-GGA-2029451 Activation of RAC1 by VAV IEA Gallus gallus 58189 R-GGA-2029467 https://reactome.org/PathwayBrowser/#/R-GGA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Gallus gallus 58189 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus 58189 R-GGA-210977 https://reactome.org/PathwayBrowser/#/R-GGA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Gallus gallus 58189 R-GGA-2130641 https://reactome.org/PathwayBrowser/#/R-GGA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Gallus gallus 58189 R-GGA-2130725 https://reactome.org/PathwayBrowser/#/R-GGA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Gallus gallus 58189 R-GGA-2179407 https://reactome.org/PathwayBrowser/#/R-GGA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Gallus gallus 58189 R-GGA-2424476 https://reactome.org/PathwayBrowser/#/R-GGA-2424476 Activation of RAC1 by VAV2/3 IEA Gallus gallus 58189 R-GGA-2424477 https://reactome.org/PathwayBrowser/#/R-GGA-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Gallus gallus 58189 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus 58189 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus 58189 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus 58189 R-GGA-2730840 https://reactome.org/PathwayBrowser/#/R-GGA-2730840 Activation of RAC1 by VAV IEA Gallus gallus 58189 R-GGA-350769 https://reactome.org/PathwayBrowser/#/R-GGA-350769 trans-Golgi Network Coat Activation IEA Gallus gallus 58189 R-GGA-354173 https://reactome.org/PathwayBrowser/#/R-GGA-354173 Activation of Rap1 by cytosolic GEFs IEA Gallus gallus 58189 R-GGA-372724 https://reactome.org/PathwayBrowser/#/R-GGA-372724 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] TAS Gallus gallus 58189 R-GGA-372741 https://reactome.org/PathwayBrowser/#/R-GGA-372741 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] TAS Gallus gallus 58189 R-GGA-372819 https://reactome.org/PathwayBrowser/#/R-GGA-372819 PCK2 phosphorylates OA to yield PEP IEA Gallus gallus 58189 R-GGA-372980 https://reactome.org/PathwayBrowser/#/R-GGA-372980 succinylCoA + GDP + Pi <=> succinate + CoASH + GTP TAS Gallus gallus 58189 R-GGA-373148 https://reactome.org/PathwayBrowser/#/R-GGA-373148 succinate + CoASH + GTP <=> succinylCoA + GDP + Pi TAS Gallus gallus 58189 R-GGA-377186 https://reactome.org/PathwayBrowser/#/R-GGA-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Gallus gallus 58189 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 58189 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 58189 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 58189 R-GGA-380979 https://reactome.org/PathwayBrowser/#/R-GGA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Gallus gallus 58189 R-GGA-381727 https://reactome.org/PathwayBrowser/#/R-GGA-381727 RAP1A exchanges GDP for GTP IEA Gallus gallus 58189 R-GGA-389348 https://reactome.org/PathwayBrowser/#/R-GGA-389348 Activation of Rac1 by pVav1 IEA Gallus gallus 58189 R-GGA-389350 https://reactome.org/PathwayBrowser/#/R-GGA-389350 Activation of Cdc42 by pVav1 IEA Gallus gallus 58189 R-GGA-392054 https://reactome.org/PathwayBrowser/#/R-GGA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Gallus gallus 58189 R-GGA-392195 https://reactome.org/PathwayBrowser/#/R-GGA-392195 Gi activation by P2Y purinoceptor 12 IEA Gallus gallus 58189 R-GGA-392513 https://reactome.org/PathwayBrowser/#/R-GGA-392513 Rap1 signal termination by Rap1GAPs IEA Gallus gallus 58189 R-GGA-3928592 https://reactome.org/PathwayBrowser/#/R-GGA-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Gallus gallus 58189 R-GGA-3928628 https://reactome.org/PathwayBrowser/#/R-GGA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 58189 R-GGA-3928642 https://reactome.org/PathwayBrowser/#/R-GGA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 58189 R-GGA-3928651 https://reactome.org/PathwayBrowser/#/R-GGA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Gallus gallus 58189 R-GGA-3965444 https://reactome.org/PathwayBrowser/#/R-GGA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Gallus gallus 58189 R-GGA-4093336 https://reactome.org/PathwayBrowser/#/R-GGA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 58189 R-GGA-4093339 https://reactome.org/PathwayBrowser/#/R-GGA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Gallus gallus 58189 R-GGA-416559 https://reactome.org/PathwayBrowser/#/R-GGA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Gallus gallus 58189 R-GGA-416588 https://reactome.org/PathwayBrowser/#/R-GGA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Gallus gallus 58189 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus 58189 R-GGA-420883 https://reactome.org/PathwayBrowser/#/R-GGA-420883 Opsins act as GEFs for G alpha-t IEA Gallus gallus 58189 R-GGA-421201 https://reactome.org/PathwayBrowser/#/R-GGA-421201 inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate IEA Gallus gallus 58189 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus 58189 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus 58189 R-GGA-428750 https://reactome.org/PathwayBrowser/#/R-GGA-428750 Gq activation by TP receptor IEA Gallus gallus 58189 R-GGA-428917 https://reactome.org/PathwayBrowser/#/R-GGA-428917 G13 activation by TP receptor IEA Gallus gallus 58189 R-GGA-432706 https://reactome.org/PathwayBrowser/#/R-GGA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Gallus gallus 58189 R-GGA-432707 https://reactome.org/PathwayBrowser/#/R-GGA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Gallus gallus 58189 R-GGA-442291 https://reactome.org/PathwayBrowser/#/R-GGA-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Gallus gallus 58189 R-GGA-442314 https://reactome.org/PathwayBrowser/#/R-GGA-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Gallus gallus 58189 R-GGA-445064 https://reactome.org/PathwayBrowser/#/R-GGA-445064 Activation of Rac1 by VAV2 IEA Gallus gallus 58189 R-GGA-446208 https://reactome.org/PathwayBrowser/#/R-GGA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Gallus gallus 58189 R-GGA-446218 https://reactome.org/PathwayBrowser/#/R-GGA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Gallus gallus 58189 R-GGA-447074 https://reactome.org/PathwayBrowser/#/R-GGA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Gallus gallus 58189 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 58189 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 58189 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 58189 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 58189 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 58189 R-GGA-5218839 https://reactome.org/PathwayBrowser/#/R-GGA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Gallus gallus 58189 R-GGA-5218850 https://reactome.org/PathwayBrowser/#/R-GGA-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 58189 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Gallus gallus 58189 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus 58189 R-GGA-555065 https://reactome.org/PathwayBrowser/#/R-GGA-555065 Formation of clathrin coated vesicle IEA Gallus gallus 58189 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus 58189 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 58189 R-GGA-5623508 https://reactome.org/PathwayBrowser/#/R-GGA-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Gallus gallus 58189 R-GGA-5623513 https://reactome.org/PathwayBrowser/#/R-GGA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Gallus gallus 58189 R-GGA-5623519 https://reactome.org/PathwayBrowser/#/R-GGA-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Gallus gallus 58189 R-GGA-5623521 https://reactome.org/PathwayBrowser/#/R-GGA-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus 58189 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus 58189 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus 58189 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus 58189 R-GGA-5653957 https://reactome.org/PathwayBrowser/#/R-GGA-5653957 Rag dimer formation IEA Gallus gallus 58189 R-GGA-5653968 https://reactome.org/PathwayBrowser/#/R-GGA-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Gallus gallus 58189 R-GGA-5653974 https://reactome.org/PathwayBrowser/#/R-GGA-5653974 Ragulator binds Rag dimers IEA Gallus gallus 58189 R-GGA-5654392 https://reactome.org/PathwayBrowser/#/R-GGA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-5654402 https://reactome.org/PathwayBrowser/#/R-GGA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-5654413 https://reactome.org/PathwayBrowser/#/R-GGA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-5654426 https://reactome.org/PathwayBrowser/#/R-GGA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-5654600 https://reactome.org/PathwayBrowser/#/R-GGA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-5654618 https://reactome.org/PathwayBrowser/#/R-GGA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-5654647 https://reactome.org/PathwayBrowser/#/R-GGA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-5654663 https://reactome.org/PathwayBrowser/#/R-GGA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-5658231 https://reactome.org/PathwayBrowser/#/R-GGA-5658231 RAS GAPs stimulate RAS GTPase activity IEA Gallus gallus 58189 R-GGA-5672010 https://reactome.org/PathwayBrowser/#/R-GGA-5672010 Active MTORC1 phosphorylates ULK1 IEA Gallus gallus 58189 R-GGA-5672017 https://reactome.org/PathwayBrowser/#/R-GGA-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Gallus gallus 58189 R-GGA-5672817 https://reactome.org/PathwayBrowser/#/R-GGA-5672817 Active MTORC1 binds the ULK1 complex IEA Gallus gallus 58189 R-GGA-5672824 https://reactome.org/PathwayBrowser/#/R-GGA-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Gallus gallus 58189 R-GGA-5672828 https://reactome.org/PathwayBrowser/#/R-GGA-5672828 mTORC1 phosphorylates AKT1S1 IEA Gallus gallus 58189 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-5673768 https://reactome.org/PathwayBrowser/#/R-GGA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Gallus gallus 58189 R-GGA-5675790 https://reactome.org/PathwayBrowser/#/R-GGA-5675790 MTORC1 dissociates from ULK complex IEA Gallus gallus 58189 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus 58189 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus 58189 R-GGA-6788611 https://reactome.org/PathwayBrowser/#/R-GGA-6788611 HYKK phosphorylates 5HLYS IEA Gallus gallus 58189 R-GGA-6807868 https://reactome.org/PathwayBrowser/#/R-GGA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Gallus gallus 58189 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus 58189 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus 58189 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus 58189 R-GGA-6811418 https://reactome.org/PathwayBrowser/#/R-GGA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Gallus gallus 58189 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus 58189 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus 58189 R-GGA-6811428 https://reactome.org/PathwayBrowser/#/R-GGA-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Gallus gallus 58189 R-GGA-6811429 https://reactome.org/PathwayBrowser/#/R-GGA-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Gallus gallus 58189 R-GGA-6814671 https://reactome.org/PathwayBrowser/#/R-GGA-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Gallus gallus 58189 R-GGA-6814682 https://reactome.org/PathwayBrowser/#/R-GGA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Gallus gallus 58189 R-GGA-70241 https://reactome.org/PathwayBrowser/#/R-GGA-70241 PCK1 phosphorylates OA to yield PEP IEA Gallus gallus 58189 R-GGA-71775 https://reactome.org/PathwayBrowser/#/R-GGA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Gallus gallus 58189 R-GGA-72670 https://reactome.org/PathwayBrowser/#/R-GGA-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Gallus gallus 58189 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus 58189 R-GGA-72722 https://reactome.org/PathwayBrowser/#/R-GGA-72722 eIF2 activation IEA Gallus gallus 58189 R-GGA-73788 https://reactome.org/PathwayBrowser/#/R-GGA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Gallus gallus 58189 R-GGA-749453 https://reactome.org/PathwayBrowser/#/R-GGA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Gallus gallus 58189 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus 58189 R-GGA-8847534 https://reactome.org/PathwayBrowser/#/R-GGA-8847534 RAB43 hydrolyses GTP IEA Gallus gallus 58189 R-GGA-8847883 https://reactome.org/PathwayBrowser/#/R-GGA-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Gallus gallus 58189 R-GGA-8848618 https://reactome.org/PathwayBrowser/#/R-GGA-8848618 Activation of RAC1 by the PXN:CRK complex IEA Gallus gallus 58189 R-GGA-8849082 https://reactome.org/PathwayBrowser/#/R-GGA-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Gallus gallus 58189 R-GGA-8849350 https://reactome.org/PathwayBrowser/#/R-GGA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Gallus gallus 58189 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus 58189 R-GGA-8850040 https://reactome.org/PathwayBrowser/#/R-GGA-8850040 RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER IEA Gallus gallus 58189 R-GGA-8850041 https://reactome.org/PathwayBrowser/#/R-GGA-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Gallus gallus 58189 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58189 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58189 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58189 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58189 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58189 R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58189 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58189 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58189 R-GGA-8851827 https://reactome.org/PathwayBrowser/#/R-GGA-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Gallus gallus 58189 R-GGA-8851877 https://reactome.org/PathwayBrowser/#/R-GGA-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Gallus gallus 58189 R-GGA-8851899 https://reactome.org/PathwayBrowser/#/R-GGA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Gallus gallus 58189 R-GGA-8854173 https://reactome.org/PathwayBrowser/#/R-GGA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Gallus gallus 58189 R-GGA-8854255 https://reactome.org/PathwayBrowser/#/R-GGA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 58189 R-GGA-8854612 https://reactome.org/PathwayBrowser/#/R-GGA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Gallus gallus 58189 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus 58189 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus 58189 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus 58189 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus 58189 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus 58189 R-GGA-8875318 https://reactome.org/PathwayBrowser/#/R-GGA-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Gallus gallus 58189 R-GGA-8875320 https://reactome.org/PathwayBrowser/#/R-GGA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Gallus gallus 58189 R-GGA-8875568 https://reactome.org/PathwayBrowser/#/R-GGA-8875568 RAPGEF1 activates RAP1 IEA Gallus gallus 58189 R-GGA-8875591 https://reactome.org/PathwayBrowser/#/R-GGA-8875591 DOCK7 activates RAC1 IEA Gallus gallus 58189 R-GGA-8876188 https://reactome.org/PathwayBrowser/#/R-GGA-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Gallus gallus 58189 R-GGA-8876190 https://reactome.org/PathwayBrowser/#/R-GGA-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Gallus gallus 58189 R-GGA-8876191 https://reactome.org/PathwayBrowser/#/R-GGA-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Gallus gallus 58189 R-GGA-8876193 https://reactome.org/PathwayBrowser/#/R-GGA-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Gallus gallus 58189 R-GGA-8876454 https://reactome.org/PathwayBrowser/#/R-GGA-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Gallus gallus 58189 R-GGA-8876616 https://reactome.org/PathwayBrowser/#/R-GGA-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Gallus gallus 58189 R-GGA-8876837 https://reactome.org/PathwayBrowser/#/R-GGA-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Gallus gallus 58189 R-GGA-8877308 https://reactome.org/PathwayBrowser/#/R-GGA-8877308 MADD exchanges GTP for GDP on RAB27 IEA Gallus gallus 58189 R-GGA-8877311 https://reactome.org/PathwayBrowser/#/R-GGA-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Gallus gallus 58189 R-GGA-8877451 https://reactome.org/PathwayBrowser/#/R-GGA-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Gallus gallus 58189 R-GGA-8877612 https://reactome.org/PathwayBrowser/#/R-GGA-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Gallus gallus 58189 R-GGA-8877760 https://reactome.org/PathwayBrowser/#/R-GGA-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Gallus gallus 58189 R-GGA-8877813 https://reactome.org/PathwayBrowser/#/R-GGA-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Gallus gallus 58189 R-GGA-8877998 https://reactome.org/PathwayBrowser/#/R-GGA-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Gallus gallus 58189 R-GGA-8938815 https://reactome.org/PathwayBrowser/#/R-GGA-8938815 RNF152 polyubiquitinates RRAGA IEA Gallus gallus 58189 R-GGA-8938829 https://reactome.org/PathwayBrowser/#/R-GGA-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 IEA Gallus gallus 58189 R-GGA-8941613 https://reactome.org/PathwayBrowser/#/R-GGA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-8941618 https://reactome.org/PathwayBrowser/#/R-GGA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-8941623 https://reactome.org/PathwayBrowser/#/R-GGA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-8941628 https://reactome.org/PathwayBrowser/#/R-GGA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus 58189 R-GGA-8944454 https://reactome.org/PathwayBrowser/#/R-GGA-8944454 mTORC1 phosphorylates MAF1 IEA Gallus gallus 58189 R-GGA-8944457 https://reactome.org/PathwayBrowser/#/R-GGA-8944457 MAF1 translocates to the nucleus IEA Gallus gallus 58189 R-GGA-8951498 https://reactome.org/PathwayBrowser/#/R-GGA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Gallus gallus 58189 R-GGA-8951586 https://reactome.org/PathwayBrowser/#/R-GGA-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Gallus gallus 58189 R-GGA-8952716 https://reactome.org/PathwayBrowser/#/R-GGA-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Gallus gallus 58189 R-GGA-8952726 https://reactome.org/PathwayBrowser/#/R-GGA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Gallus gallus 58189 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus 58189 R-GGA-8981353 https://reactome.org/PathwayBrowser/#/R-GGA-8981353 RASA1 stimulates RAS GTPase activity IEA Gallus gallus 58189 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus 58189 R-GGA-8982012 https://reactome.org/PathwayBrowser/#/R-GGA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Gallus gallus 58189 R-GGA-8982018 https://reactome.org/PathwayBrowser/#/R-GGA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Gallus gallus 58189 R-GGA-8982020 https://reactome.org/PathwayBrowser/#/R-GGA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Gallus gallus 58189 R-GGA-8982021 https://reactome.org/PathwayBrowser/#/R-GGA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Gallus gallus 58189 R-GGA-8982025 https://reactome.org/PathwayBrowser/#/R-GGA-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Gallus gallus 58189 R-GGA-8982026 https://reactome.org/PathwayBrowser/#/R-GGA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Gallus gallus 58189 R-GGA-8985594 https://reactome.org/PathwayBrowser/#/R-GGA-8985594 MYO9B inactivates RHOA IEA Gallus gallus 58189 R-GGA-9012835 https://reactome.org/PathwayBrowser/#/R-GGA-9012835 GDIs block activation of RHOA IEA Gallus gallus 58189 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus 58189 R-GGA-9013023 https://reactome.org/PathwayBrowser/#/R-GGA-9013023 RHOB GEFs activate RHOB IEA Gallus gallus 58189 R-GGA-9013108 https://reactome.org/PathwayBrowser/#/R-GGA-9013108 GDIs block activation of RHOC IEA Gallus gallus 58189 R-GGA-9013109 https://reactome.org/PathwayBrowser/#/R-GGA-9013109 RHOC GEFs activate RHOC IEA Gallus gallus 58189 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus 58189 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus 58189 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus 58189 R-GGA-9013147 https://reactome.org/PathwayBrowser/#/R-GGA-9013147 RAC1 GDIs block activation of RAC1 IEA Gallus gallus 58189 R-GGA-9013158 https://reactome.org/PathwayBrowser/#/R-GGA-9013158 CDC42 GDIs block activation of CDC42 IEA Gallus gallus 58189 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus 58189 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus 58189 R-GGA-9013435 https://reactome.org/PathwayBrowser/#/R-GGA-9013435 RHOD auto-activates IEA Gallus gallus 58189 R-GGA-9013437 https://reactome.org/PathwayBrowser/#/R-GGA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Gallus gallus 58189 R-GGA-9014293 https://reactome.org/PathwayBrowser/#/R-GGA-9014293 RAC2 GDIs block activation of RAC2 IEA Gallus gallus 58189 R-GGA-9014295 https://reactome.org/PathwayBrowser/#/R-GGA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Gallus gallus 58189 R-GGA-9014296 https://reactome.org/PathwayBrowser/#/R-GGA-9014296 RAC2 GEFs activate RAC2 IEA Gallus gallus 58189 R-GGA-9014433 https://reactome.org/PathwayBrowser/#/R-GGA-9014433 RHOG GEFs activate RHOG IEA Gallus gallus 58189 R-GGA-9014434 https://reactome.org/PathwayBrowser/#/R-GGA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Gallus gallus 58189 R-GGA-9014456 https://reactome.org/PathwayBrowser/#/R-GGA-9014456 GDIs block activation of RHOG IEA Gallus gallus 58189 R-GGA-9017488 https://reactome.org/PathwayBrowser/#/R-GGA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Gallus gallus 58189 R-GGA-9017491 https://reactome.org/PathwayBrowser/#/R-GGA-9017491 RHOJ GEFs activate RHOJ IEA Gallus gallus 58189 R-GGA-9018745 https://reactome.org/PathwayBrowser/#/R-GGA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Gallus gallus 58189 R-GGA-9018747 https://reactome.org/PathwayBrowser/#/R-GGA-9018747 RHOQ GEFs activate RHOQ IEA Gallus gallus 58189 R-GGA-9018768 https://reactome.org/PathwayBrowser/#/R-GGA-9018768 RHOU auto-activates IEA Gallus gallus 58189 R-GGA-9018798 https://reactome.org/PathwayBrowser/#/R-GGA-9018798 RHOV binds GTP IEA Gallus gallus 58189 R-GGA-9018804 https://reactome.org/PathwayBrowser/#/R-GGA-9018804 RAC3 GEFs activate RAC3 IEA Gallus gallus 58189 R-GGA-9018806 https://reactome.org/PathwayBrowser/#/R-GGA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Gallus gallus 58189 R-GGA-9018807 https://reactome.org/PathwayBrowser/#/R-GGA-9018807 RAC3 GDIs block activation of RAC3 IEA Gallus gallus 58189 R-GGA-9018814 https://reactome.org/PathwayBrowser/#/R-GGA-9018814 RHOT1 hydrolyzes GTP IEA Gallus gallus 58189 R-GGA-9018826 https://reactome.org/PathwayBrowser/#/R-GGA-9018826 RHOT2 hydrolyzes GTP IEA Gallus gallus 58189 R-GGA-9032798 https://reactome.org/PathwayBrowser/#/R-GGA-9032798 DOCK3 activates RAC1 IEA Gallus gallus 58189 R-GGA-9036301 https://reactome.org/PathwayBrowser/#/R-GGA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Gallus gallus 58189 R-GGA-9036307 https://reactome.org/PathwayBrowser/#/R-GGA-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Gallus gallus 58189 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus 58189 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus 58189 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus 58189 R-GGA-939265 https://reactome.org/PathwayBrowser/#/R-GGA-939265 Activation of Rap1 by membrane-associated GEFs IEA Gallus gallus 58189 R-GGA-9603984 https://reactome.org/PathwayBrowser/#/R-GGA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Gallus gallus 58189 R-GGA-9605682 https://reactome.org/PathwayBrowser/#/R-GGA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Gallus gallus 58189 R-GGA-9607304 https://reactome.org/PathwayBrowser/#/R-GGA-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Gallus gallus 58189 R-GGA-9624845 https://reactome.org/PathwayBrowser/#/R-GGA-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Gallus gallus 58189 R-GGA-9624893 https://reactome.org/PathwayBrowser/#/R-GGA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Gallus gallus 58189 R-GGA-9632906 https://reactome.org/PathwayBrowser/#/R-GGA-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Gallus gallus 58189 R-GGA-9632918 https://reactome.org/PathwayBrowser/#/R-GGA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Gallus gallus 58189 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus 58189 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus 58189 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus 58189 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus 58189 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus 58189 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus 58189 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus 58189 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus 58189 R-GGA-9646679 https://reactome.org/PathwayBrowser/#/R-GGA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Gallus gallus 58189 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus 58189 R-GGA-9649733 https://reactome.org/PathwayBrowser/#/R-GGA-9649733 mature p21 RAS binds GDP IEA Gallus gallus 58189 R-GGA-9649735 https://reactome.org/PathwayBrowser/#/R-GGA-9649735 Intrinsic nucleotide exchange on RAS IEA Gallus gallus 58189 R-GGA-9649736 https://reactome.org/PathwayBrowser/#/R-GGA-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Gallus gallus 58189 R-GGA-9693111 https://reactome.org/PathwayBrowser/#/R-GGA-9693111 RHOF auto-activates IEA Gallus gallus 58189 R-GGA-9693282 https://reactome.org/PathwayBrowser/#/R-GGA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Gallus gallus 58189 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 58189 R-GGA-9726862 https://reactome.org/PathwayBrowser/#/R-GGA-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Gallus gallus 58189 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 58189 R-GGA-9751201 https://reactome.org/PathwayBrowser/#/R-GGA-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Gallus gallus 58189 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus 58189 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus 58189 R-HSA-1008248 https://reactome.org/PathwayBrowser/#/R-HSA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase TAS Homo sapiens 58189 R-HSA-1028788 https://reactome.org/PathwayBrowser/#/R-HSA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP TAS Homo sapiens 58189 R-HSA-109807 https://reactome.org/PathwayBrowser/#/R-HSA-109807 GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS IEA Homo sapiens 58189 R-HSA-109817 https://reactome.org/PathwayBrowser/#/R-HSA-109817 GRB2:SOS1:p-Y-IRS1,p-Y-IRS2 mediated nucleotide exchange of RAS IEA Homo sapiens 58189 R-HSA-110133 https://reactome.org/PathwayBrowser/#/R-HSA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) TAS Homo sapiens 58189 R-HSA-111524 https://reactome.org/PathwayBrowser/#/R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] TAS Homo sapiens 58189 R-HSA-112037 https://reactome.org/PathwayBrowser/#/R-HSA-112037 Inactivation of PLC beta TAS Homo sapiens 58189 R-HSA-114544 https://reactome.org/PathwayBrowser/#/R-HSA-114544 p115-RhoGEF activation of RHOA TAS Homo sapiens 58189 R-HSA-114552 https://reactome.org/PathwayBrowser/#/R-HSA-114552 Thrombin-activated PARs activate G12/13 TAS Homo sapiens 58189 R-HSA-114558 https://reactome.org/PathwayBrowser/#/R-HSA-114558 Thrombin-activated PARs activate Gq TAS Homo sapiens 58189 R-HSA-1168636 https://reactome.org/PathwayBrowser/#/R-HSA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP TAS Homo sapiens 58189 R-HSA-1225951 https://reactome.org/PathwayBrowser/#/R-HSA-1225951 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants) TAS Homo sapiens 58189 R-HSA-1225957 https://reactome.org/PathwayBrowser/#/R-HSA-1225957 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and ligand-responsive p-6Y-EGFR mutants) TAS Homo sapiens 58189 R-HSA-1250383 https://reactome.org/PathwayBrowser/#/R-HSA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 TAS Homo sapiens 58189 R-HSA-1250463 https://reactome.org/PathwayBrowser/#/R-HSA-1250463 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-SHC1:Phosphorylated ERBB2 heterodimers IEA Homo sapiens 58189 R-HSA-1250498 https://reactome.org/PathwayBrowser/#/R-HSA-1250498 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and phosphorylated EGFR:ERBB2 heterodimers. IEA Homo sapiens 58189 R-HSA-1306972 https://reactome.org/PathwayBrowser/#/R-HSA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers TAS Homo sapiens 58189 R-HSA-141671 https://reactome.org/PathwayBrowser/#/R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex IEA Homo sapiens 58189 R-HSA-141673 https://reactome.org/PathwayBrowser/#/R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex IEA Homo sapiens 58189 R-HSA-1433415 https://reactome.org/PathwayBrowser/#/R-HSA-1433415 Activation of RAC1 TAS Homo sapiens 58189 R-HSA-1433471 https://reactome.org/PathwayBrowser/#/R-HSA-1433471 Activation of RAS by p-KIT bound SOS1 TAS Homo sapiens 58189 R-HSA-1445143 https://reactome.org/PathwayBrowser/#/R-HSA-1445143 RAB8A,10,13,14 hydrolyze GTP IEA Homo sapiens 58189 R-HSA-156913 https://reactome.org/PathwayBrowser/#/R-HSA-156913 Regeneration of eEF1A:GTP by eEF1B activity TAS Homo sapiens 58189 R-HSA-156915 https://reactome.org/PathwayBrowser/#/R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction IEA Homo sapiens 58189 R-HSA-156923 https://reactome.org/PathwayBrowser/#/R-HSA-156923 Hydrolysis of eEF1A:GTP IEA Homo sapiens 58189 R-HSA-162721 https://reactome.org/PathwayBrowser/#/R-HSA-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose TAS Homo sapiens 58189 R-HSA-1638803 https://reactome.org/PathwayBrowser/#/R-HSA-1638803 Phosphorylation of cohesin by PLK1 at centromeres TAS Homo sapiens 58189 R-HSA-1638821 https://reactome.org/PathwayBrowser/#/R-HSA-1638821 PP2A-B56 dephosphorylates centromeric cohesin TAS Homo sapiens 58189 R-HSA-164381 https://reactome.org/PathwayBrowser/#/R-HSA-164381 G alpha (s) auto-inactivates by hydrolysing GTP to GDP TAS Homo sapiens 58189 R-HSA-165055 https://reactome.org/PathwayBrowser/#/R-HSA-165055 Hydrolysis of Ran:GTP to Ran:GDP TAS Homo sapiens 58189 R-HSA-165195 https://reactome.org/PathwayBrowser/#/R-HSA-165195 GTP loading by Rheb TAS Homo sapiens 58189 R-HSA-165680 https://reactome.org/PathwayBrowser/#/R-HSA-165680 Formation of active mTORC1 complex TAS Homo sapiens 58189 R-HSA-165692 https://reactome.org/PathwayBrowser/#/R-HSA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 TAS Homo sapiens 58189 R-HSA-165718 https://reactome.org/PathwayBrowser/#/R-HSA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) TAS Homo sapiens 58189 R-HSA-167408 https://reactome.org/PathwayBrowser/#/R-HSA-167408 The high affinity receptor complex binds to G-protein TAS Homo sapiens 58189 R-HSA-167415 https://reactome.org/PathwayBrowser/#/R-HSA-167415 G-protein alpha subunit is inactivated TAS Homo sapiens 58189 R-HSA-167419 https://reactome.org/PathwayBrowser/#/R-HSA-167419 The receptor:G-protein complex releases GDP TAS Homo sapiens 58189 R-HSA-167433 https://reactome.org/PathwayBrowser/#/R-HSA-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit TAS Homo sapiens 58189 R-HSA-168880 https://reactome.org/PathwayBrowser/#/R-HSA-168880 vRNP Export through the nuclear pore TAS Homo sapiens 58189 R-HSA-169904 https://reactome.org/PathwayBrowser/#/R-HSA-169904 C3G stimulates nucleotide exchange on Rap1 TAS Homo sapiens 58189 R-HSA-170026 https://reactome.org/PathwayBrowser/#/R-HSA-170026 Protons are translocated from the intermembrane space to the matrix TAS Homo sapiens 58189 R-HSA-170666 https://reactome.org/PathwayBrowser/#/R-HSA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf TAS Homo sapiens 58189 R-HSA-170674 https://reactome.org/PathwayBrowser/#/R-HSA-170674 Dissociation of the Gi alpha:G olf complex TAS Homo sapiens 58189 R-HSA-170677 https://reactome.org/PathwayBrowser/#/R-HSA-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates TAS Homo sapiens 58189 R-HSA-170685 https://reactome.org/PathwayBrowser/#/R-HSA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf TAS Homo sapiens 58189 R-HSA-170686 https://reactome.org/PathwayBrowser/#/R-HSA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha TAS Homo sapiens 58189 R-HSA-170979 https://reactome.org/PathwayBrowser/#/R-HSA-170979 (Frs2)C3G stimulates nucleotide exchange on Rap1 IEA Homo sapiens 58189 R-HSA-171026 https://reactome.org/PathwayBrowser/#/R-HSA-171026 Guanine nucleotide exchange on RAL IEA Homo sapiens 58189 R-HSA-177501 https://reactome.org/PathwayBrowser/#/R-HSA-177501 Endocytosis (internalization) of clathrin-coated vesicle IEA Homo sapiens 58189 R-HSA-177938 https://reactome.org/PathwayBrowser/#/R-HSA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) TAS Homo sapiens 58189 R-HSA-177945 https://reactome.org/PathwayBrowser/#/R-HSA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) TAS Homo sapiens 58189 R-HSA-186834 https://reactome.org/PathwayBrowser/#/R-HSA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) TAS Homo sapiens 58189 R-HSA-187697 https://reactome.org/PathwayBrowser/#/R-HSA-187697 TRKA recruits RIT and RIN IEA Homo sapiens 58189 R-HSA-187746 https://reactome.org/PathwayBrowser/#/R-HSA-187746 RIT/RIN are activated IEA Homo sapiens 58189 R-HSA-190520 https://reactome.org/PathwayBrowser/#/R-HSA-190520 Association of Golgi transport vesicles with microtubules TAS Homo sapiens 58189 R-HSA-190877 https://reactome.org/PathwayBrowser/#/R-HSA-190877 Insertion of connexons into the plasma membrane resulting in the formation of hemi-channels IEA Homo sapiens 58189 R-HSA-191737 https://reactome.org/PathwayBrowser/#/R-HSA-191737 Docking of connexons into junctional, double-membrane spanning channels IEA Homo sapiens 58189 R-HSA-193646 https://reactome.org/PathwayBrowser/#/R-HSA-193646 NGF binding to p75NTR inactivates RHOA TAS Homo sapiens 58189 R-HSA-193668 https://reactome.org/PathwayBrowser/#/R-HSA-193668 p75NTR and RHOA-GDI interact TAS Homo sapiens 58189 R-HSA-193696 https://reactome.org/PathwayBrowser/#/R-HSA-193696 The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA TAS Homo sapiens 58189 R-HSA-194518 https://reactome.org/PathwayBrowser/#/R-HSA-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth TAS Homo sapiens 58189 R-HSA-2029445 https://reactome.org/PathwayBrowser/#/R-HSA-2029445 An unknown GEF exchanges GTP for GDP on CDC42:GDP TAS Homo sapiens 58189 R-HSA-2029451 https://reactome.org/PathwayBrowser/#/R-HSA-2029451 Activation of RAC1 by VAV TAS Homo sapiens 58189 R-HSA-2029467 https://reactome.org/PathwayBrowser/#/R-HSA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO TAS Homo sapiens 58189 R-HSA-203906 https://reactome.org/PathwayBrowser/#/R-HSA-203906 Exportin complex translocates pre-miRNA to cytosol TAS Homo sapiens 58189 R-HSA-203977 https://reactome.org/PathwayBrowser/#/R-HSA-203977 SAR1 Activation And Membrane Binding TAS Homo sapiens 58189 R-HSA-205039 https://reactome.org/PathwayBrowser/#/R-HSA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor TAS Homo sapiens 58189 R-HSA-210977 https://reactome.org/PathwayBrowser/#/R-HSA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) TAS Homo sapiens 58189 R-HSA-2130641 https://reactome.org/PathwayBrowser/#/R-HSA-2130641 Translocation of TGN-lysosome vesicle to lysosome TAS Homo sapiens 58189 R-HSA-2130725 https://reactome.org/PathwayBrowser/#/R-HSA-2130725 Internalization of MHC II:Ii clathrin coated vesicle TAS Homo sapiens 58189 R-HSA-2179407 https://reactome.org/PathwayBrowser/#/R-HSA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) TAS Homo sapiens 58189 R-HSA-2213248 https://reactome.org/PathwayBrowser/#/R-HSA-2213248 Transport of antigen loaded MHC II molecules to surface TAS Homo sapiens 58189 R-HSA-2255343 https://reactome.org/PathwayBrowser/#/R-HSA-2255343 RAB8A,10,13,14 exchange GDP for GTP IEA Homo sapiens 58189 R-HSA-2316347 https://reactome.org/PathwayBrowser/#/R-HSA-2316347 RAB4A:GTP binds KIF3 and activates KIF3 IEA Homo sapiens 58189 R-HSA-2424476 https://reactome.org/PathwayBrowser/#/R-HSA-2424476 Activation of RAC1 by VAV2/3 TAS Homo sapiens 58189 R-HSA-2424477 https://reactome.org/PathwayBrowser/#/R-HSA-2424477 SOS mediated nucleotide exchange of RAS (SHC) TAS Homo sapiens 58189 R-HSA-2467809 https://reactome.org/PathwayBrowser/#/R-HSA-2467809 ESPL1 (Separase) cleaves centromeric cohesin TAS Homo sapiens 58189 R-HSA-2467811 https://reactome.org/PathwayBrowser/#/R-HSA-2467811 Separation of sister chromatids TAS Homo sapiens 58189 R-HSA-2468287 https://reactome.org/PathwayBrowser/#/R-HSA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres TAS Homo sapiens 58189 R-HSA-2484822 https://reactome.org/PathwayBrowser/#/R-HSA-2484822 Kinetochore assembly TAS Homo sapiens 58189 R-HSA-2485180 https://reactome.org/PathwayBrowser/#/R-HSA-2485180 MII catalyses GDP/GTP exchange on Gt IEA Homo sapiens 58189 R-HSA-2584246 https://reactome.org/PathwayBrowser/#/R-HSA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP TAS Homo sapiens 58189 R-HSA-2730840 https://reactome.org/PathwayBrowser/#/R-HSA-2730840 Activation of RAC1 by VAV TAS Homo sapiens 58189 R-HSA-350769 https://reactome.org/PathwayBrowser/#/R-HSA-350769 trans-Golgi Network Coat Activation TAS Homo sapiens 58189 R-HSA-354173 https://reactome.org/PathwayBrowser/#/R-HSA-354173 Activation of Rap1 by cytosolic GEFs TAS Homo sapiens 58189 R-HSA-372819 https://reactome.org/PathwayBrowser/#/R-HSA-372819 PCK2 phosphorylates OA to yield PEP TAS Homo sapiens 58189 R-HSA-375302 https://reactome.org/PathwayBrowser/#/R-HSA-375302 Kinetochore capture of astral microtubules TAS Homo sapiens 58189 R-HSA-377186 https://reactome.org/PathwayBrowser/#/R-HSA-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) TAS Homo sapiens 58189 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 58189 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 58189 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 58189 R-HSA-380316 https://reactome.org/PathwayBrowser/#/R-HSA-380316 Association of NuMA with microtubules TAS Homo sapiens 58189 R-HSA-380979 https://reactome.org/PathwayBrowser/#/R-HSA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP TAS Homo sapiens 58189 R-HSA-381612 https://reactome.org/PathwayBrowser/#/R-HSA-381612 GLP1R binds GLP1 TAS Homo sapiens 58189 R-HSA-381706 https://reactome.org/PathwayBrowser/#/R-HSA-381706 GLP1R:GLP1 activates G(s) IEA Homo sapiens 58189 R-HSA-381727 https://reactome.org/PathwayBrowser/#/R-HSA-381727 RAP1A exchanges GDP for GTP TAS Homo sapiens 58189 R-HSA-389348 https://reactome.org/PathwayBrowser/#/R-HSA-389348 Activation of Rac1 by pVav1 TAS Homo sapiens 58189 R-HSA-389350 https://reactome.org/PathwayBrowser/#/R-HSA-389350 Activation of Cdc42 by pVav1 TAS Homo sapiens 58189 R-HSA-392054 https://reactome.org/PathwayBrowser/#/R-HSA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras TAS Homo sapiens 58189 R-HSA-392195 https://reactome.org/PathwayBrowser/#/R-HSA-392195 Gi activation by P2Y purinoceptor 12 TAS Homo sapiens 58189 R-HSA-392513 https://reactome.org/PathwayBrowser/#/R-HSA-392513 Rap1 signal termination by Rap1GAPs TAS Homo sapiens 58189 R-HSA-392852 https://reactome.org/PathwayBrowser/#/R-HSA-392852 Activated prostacyclin receptor binds G-protein Gs TAS Homo sapiens 58189 R-HSA-3928592 https://reactome.org/PathwayBrowser/#/R-HSA-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it TAS Homo sapiens 58189 R-HSA-3928628 https://reactome.org/PathwayBrowser/#/R-HSA-3928628 VAV exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 58189 R-HSA-3928632 https://reactome.org/PathwayBrowser/#/R-HSA-3928632 ITSN1 exchanges GTP for GDP on CDC42, activating it IEA Homo sapiens 58189 R-HSA-3928642 https://reactome.org/PathwayBrowser/#/R-HSA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 58189 R-HSA-3928651 https://reactome.org/PathwayBrowser/#/R-HSA-3928651 NGEF exchanges GTP for GDP on RHOA TAS Homo sapiens 58189 R-HSA-392870 https://reactome.org/PathwayBrowser/#/R-HSA-392870 Gs activation by prostacyclin receptor TAS Homo sapiens 58189 R-HSA-3965441 https://reactome.org/PathwayBrowser/#/R-HSA-3965441 FZD recruits trimeric G-proteins IEA Homo sapiens 58189 R-HSA-3965444 https://reactome.org/PathwayBrowser/#/R-HSA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange TAS Homo sapiens 58189 R-HSA-399938 https://reactome.org/PathwayBrowser/#/R-HSA-399938 Activation of Rac1 by FARP2 IEA Homo sapiens 58189 R-HSA-399995 https://reactome.org/PathwayBrowser/#/R-HSA-399995 Muscarinic Acetylcholine Receptor M3 activates Gq IEA Homo sapiens 58189 R-HSA-400092 https://reactome.org/PathwayBrowser/#/R-HSA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins TAS Homo sapiens 58189 R-HSA-4093336 https://reactome.org/PathwayBrowser/#/R-HSA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 58189 R-HSA-4093339 https://reactome.org/PathwayBrowser/#/R-HSA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it TAS Homo sapiens 58189 R-HSA-416530 https://reactome.org/PathwayBrowser/#/R-HSA-416530 FFAR1:FFAR1 ligands activate Gq TAS Homo sapiens 58189 R-HSA-416559 https://reactome.org/PathwayBrowser/#/R-HSA-416559 Inactivation of Rho-GTP by p190RhoGAP TAS Homo sapiens 58189 R-HSA-416588 https://reactome.org/PathwayBrowser/#/R-HSA-416588 Activation of Rho by LARG and PDZ-RhoGEF TAS Homo sapiens 58189 R-HSA-418579 https://reactome.org/PathwayBrowser/#/R-HSA-418579 Gq activation by P2Y purinoceptor 1 IEA Homo sapiens 58189 R-HSA-418850 https://reactome.org/PathwayBrowser/#/R-HSA-418850 Activation of Cdc42 TAS Homo sapiens 58189 R-HSA-418856 https://reactome.org/PathwayBrowser/#/R-HSA-418856 Activation of Rac1 TAS Homo sapiens 58189 R-HSA-419166 https://reactome.org/PathwayBrowser/#/R-HSA-419166 GEFs activate RhoA,B,C TAS Homo sapiens 58189 R-HSA-420883 https://reactome.org/PathwayBrowser/#/R-HSA-420883 Opsins act as GEFs for G alpha-t TAS Homo sapiens 58189 R-HSA-421831 https://reactome.org/PathwayBrowser/#/R-HSA-421831 trans-Golgi Network Coat Assembly TAS Homo sapiens 58189 R-HSA-421835 https://reactome.org/PathwayBrowser/#/R-HSA-421835 trans-Golgi Network Vesicle Scission TAS Homo sapiens 58189 R-HSA-428522 https://reactome.org/PathwayBrowser/#/R-HSA-428522 Inactivation of RAC1 IEA Homo sapiens 58189 R-HSA-428533 https://reactome.org/PathwayBrowser/#/R-HSA-428533 Inactivation of CDC42 IEA Homo sapiens 58189 R-HSA-428535 https://reactome.org/PathwayBrowser/#/R-HSA-428535 Activation of RAC1 by SOS IEA Homo sapiens 58189 R-HSA-428750 https://reactome.org/PathwayBrowser/#/R-HSA-428750 Gq activation by TP receptor TAS Homo sapiens 58189 R-HSA-428917 https://reactome.org/PathwayBrowser/#/R-HSA-428917 G13 activation by TP receptor TAS Homo sapiens 58189 R-HSA-432188 https://reactome.org/PathwayBrowser/#/R-HSA-432188 AVP:AVPR2 Complex binds inactive heterotrimeric G(s) complex TAS Homo sapiens 58189 R-HSA-432195 https://reactome.org/PathwayBrowser/#/R-HSA-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP TAS Homo sapiens 58189 R-HSA-432706 https://reactome.org/PathwayBrowser/#/R-HSA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly TAS Homo sapiens 58189 R-HSA-432707 https://reactome.org/PathwayBrowser/#/R-HSA-432707 trans-Golgi Network Lysosomal Vesicle Scission TAS Homo sapiens 58189 R-HSA-442273 https://reactome.org/PathwayBrowser/#/R-HSA-442273 VAV1 is a GEF for Rho/Rac family GTPases TAS Homo sapiens 58189 R-HSA-442291 https://reactome.org/PathwayBrowser/#/R-HSA-442291 VAV2 is a GEF for Rho/Rac family kinases TAS Homo sapiens 58189 R-HSA-442314 https://reactome.org/PathwayBrowser/#/R-HSA-442314 VAV3 is a GEF for Rho/Rac family kinases TAS Homo sapiens 58189 R-HSA-442732 https://reactome.org/PathwayBrowser/#/R-HSA-442732 NMDA-activated RASGRF1 activates RAS IEA Homo sapiens 58189 R-HSA-445064 https://reactome.org/PathwayBrowser/#/R-HSA-445064 Activation of Rac1 by VAV2 TAS Homo sapiens 58189 R-HSA-445071 https://reactome.org/PathwayBrowser/#/R-HSA-445071 Reinsertion of L1 into the plasma membrane TAS Homo sapiens 58189 R-HSA-445077 https://reactome.org/PathwayBrowser/#/R-HSA-445077 Transport of L1 from C-domain to P-domain IEA Homo sapiens 58189 R-HSA-446187 https://reactome.org/PathwayBrowser/#/R-HSA-446187 ALG11 transfers the fourth and fifth Man to the N-glycan precursor IEA Homo sapiens 58189 R-HSA-446208 https://reactome.org/PathwayBrowser/#/R-HSA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 TAS Homo sapiens 58189 R-HSA-446218 https://reactome.org/PathwayBrowser/#/R-HSA-446218 Addition of the first mannose to the N-glycan precursor by ALG1 TAS Homo sapiens 58189 R-HSA-447074 https://reactome.org/PathwayBrowser/#/R-HSA-447074 AMPK phosphorylates Raptor in the mTORC1 complex TAS Homo sapiens 58189 R-HSA-449718 https://reactome.org/PathwayBrowser/#/R-HSA-449718 Addition of a third mannose to the N-glycan precursor by ALG2 IEA Homo sapiens 58189 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 58189 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 58189 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 58189 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 58189 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 58189 R-HSA-5218829 https://reactome.org/PathwayBrowser/#/R-HSA-5218829 VEGF induces CDC42 activation by unknown mechanism TAS Homo sapiens 58189 R-HSA-5218839 https://reactome.org/PathwayBrowser/#/R-HSA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 TAS Homo sapiens 58189 R-HSA-5218850 https://reactome.org/PathwayBrowser/#/R-HSA-5218850 VAV exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 58189 R-HSA-5333615 https://reactome.org/PathwayBrowser/#/R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC IEA Homo sapiens 58189 R-HSA-5389839 https://reactome.org/PathwayBrowser/#/R-HSA-5389839 39S subunit binds 28S subunit:mRNA:fMet-tRNA IEA Homo sapiens 58189 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 58189 R-HSA-5419269 https://reactome.org/PathwayBrowser/#/R-HSA-5419269 TSFM binds TUFM displacing GDP IEA Homo sapiens 58189 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 58189 R-HSA-5419273 https://reactome.org/PathwayBrowser/#/R-HSA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits TAS Homo sapiens 58189 R-HSA-5419279 https://reactome.org/PathwayBrowser/#/R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) IEA Homo sapiens 58189 R-HSA-555065 https://reactome.org/PathwayBrowser/#/R-HSA-555065 Formation of clathrin coated vesicle TAS Homo sapiens 58189 R-HSA-5610733 https://reactome.org/PathwayBrowser/#/R-HSA-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules TAS Homo sapiens 58189 R-HSA-5610767 https://reactome.org/PathwayBrowser/#/R-HSA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip TAS Homo sapiens 58189 R-HSA-5617816 https://reactome.org/PathwayBrowser/#/R-HSA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A TAS Homo sapiens 58189 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 58189 R-HSA-5618328 https://reactome.org/PathwayBrowser/#/R-HSA-5618328 ATAT acetylates microtubules TAS Homo sapiens 58189 R-HSA-5618331 https://reactome.org/PathwayBrowser/#/R-HSA-5618331 HDAC6 deacetylates microtubules TAS Homo sapiens 58189 R-HSA-5621573 https://reactome.org/PathwayBrowser/#/R-HSA-5621573 CD209 activate GTPase RAS TAS Homo sapiens 58189 R-HSA-5623508 https://reactome.org/PathwayBrowser/#/R-HSA-5623508 GBF1 stimulates nucleotide exchange on ARF4 TAS Homo sapiens 58189 R-HSA-5623513 https://reactome.org/PathwayBrowser/#/R-HSA-5623513 ASAP1 stimulates GTPase activity of ARF4 TAS Homo sapiens 58189 R-HSA-5623519 https://reactome.org/PathwayBrowser/#/R-HSA-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex TAS Homo sapiens 58189 R-HSA-5623521 https://reactome.org/PathwayBrowser/#/R-HSA-5623521 RAB3IP stimulates nucleotide exchange on RAB8A TAS Homo sapiens 58189 R-HSA-5624949 https://reactome.org/PathwayBrowser/#/R-HSA-5624949 Assembly of the anterograde IFT train TAS Homo sapiens 58189 R-HSA-5624952 https://reactome.org/PathwayBrowser/#/R-HSA-5624952 Assembly of the retrograde IFT train TAS Homo sapiens 58189 R-HSA-5625416 https://reactome.org/PathwayBrowser/#/R-HSA-5625416 Anterograde IFT TAS Homo sapiens 58189 R-HSA-5625421 https://reactome.org/PathwayBrowser/#/R-HSA-5625421 The anterograde IFT train dissociates TAS Homo sapiens 58189 R-HSA-5625424 https://reactome.org/PathwayBrowser/#/R-HSA-5625424 The retrograde IFT train dissociates TAS Homo sapiens 58189 R-HSA-5625426 https://reactome.org/PathwayBrowser/#/R-HSA-5625426 Retrograde IFT TAS Homo sapiens 58189 R-HSA-5637806 https://reactome.org/PathwayBrowser/#/R-HSA-5637806 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with p-EGFRvIII) TAS Homo sapiens 58189 R-HSA-5637808 https://reactome.org/PathwayBrowser/#/R-HSA-5637808 SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with phosphorylated SHC1 and p-EGFRvIII) TAS Homo sapiens 58189 R-HSA-5653957 https://reactome.org/PathwayBrowser/#/R-HSA-5653957 Rag dimer formation TAS Homo sapiens 58189 R-HSA-5653968 https://reactome.org/PathwayBrowser/#/R-HSA-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 TAS Homo sapiens 58189 R-HSA-5653974 https://reactome.org/PathwayBrowser/#/R-HSA-5653974 Ragulator binds Rag dimers TAS Homo sapiens 58189 R-HSA-5654392 https://reactome.org/PathwayBrowser/#/R-HSA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5654402 https://reactome.org/PathwayBrowser/#/R-HSA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5654413 https://reactome.org/PathwayBrowser/#/R-HSA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5654426 https://reactome.org/PathwayBrowser/#/R-HSA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5654600 https://reactome.org/PathwayBrowser/#/R-HSA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5654618 https://reactome.org/PathwayBrowser/#/R-HSA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5654647 https://reactome.org/PathwayBrowser/#/R-HSA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5654663 https://reactome.org/PathwayBrowser/#/R-HSA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5655241 https://reactome.org/PathwayBrowser/#/R-HSA-5655241 Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5655277 https://reactome.org/PathwayBrowser/#/R-HSA-5655277 Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5655326 https://reactome.org/PathwayBrowser/#/R-HSA-5655326 Activated FGFR1 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5655347 https://reactome.org/PathwayBrowser/#/R-HSA-5655347 Activated FGFR4 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5658231 https://reactome.org/PathwayBrowser/#/R-HSA-5658231 RAS GAPs stimulate RAS GTPase activity TAS Homo sapiens 58189 R-HSA-5665809 https://reactome.org/PathwayBrowser/#/R-HSA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments TAS Homo sapiens 58189 R-HSA-5666169 https://reactome.org/PathwayBrowser/#/R-HSA-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 TAS Homo sapiens 58189 R-HSA-5672010 https://reactome.org/PathwayBrowser/#/R-HSA-5672010 Active MTORC1 phosphorylates ULK1 TAS Homo sapiens 58189 R-HSA-5672017 https://reactome.org/PathwayBrowser/#/R-HSA-5672017 Rheb in the MTORC1 complex hydrolyses GTP TAS Homo sapiens 58189 R-HSA-5672329 https://reactome.org/PathwayBrowser/#/R-HSA-5672329 IQGAP1 binds CLIP1 and microtubules TAS Homo sapiens 58189 R-HSA-5672817 https://reactome.org/PathwayBrowser/#/R-HSA-5672817 Active MTORC1 binds the ULK1 complex TAS Homo sapiens 58189 R-HSA-5672824 https://reactome.org/PathwayBrowser/#/R-HSA-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB TAS Homo sapiens 58189 R-HSA-5672828 https://reactome.org/PathwayBrowser/#/R-HSA-5672828 mTORC1 phosphorylates AKT1S1 TAS Homo sapiens 58189 R-HSA-5672843 https://reactome.org/PathwayBrowser/#/R-HSA-5672843 AKT1S1 (PRAS40) binds mTORC1 TAS Homo sapiens 58189 R-HSA-5672965 https://reactome.org/PathwayBrowser/#/R-HSA-5672965 RAS GEFs promote RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-5673768 https://reactome.org/PathwayBrowser/#/R-HSA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex TAS Homo sapiens 58189 R-HSA-5675790 https://reactome.org/PathwayBrowser/#/R-HSA-5675790 MTORC1 dissociates from ULK complex TAS Homo sapiens 58189 R-HSA-5686071 https://reactome.org/PathwayBrowser/#/R-HSA-5686071 GRB2-1:SOS1:p-Y-SHC mediated nucleotide exchange of RAS IEA Homo sapiens 58189 R-HSA-5686318 https://reactome.org/PathwayBrowser/#/R-HSA-5686318 GRB2-1:SOS1:p-3Y-SHC1 mediated nucleotide exchange of RAS IEA Homo sapiens 58189 R-HSA-5693925 https://reactome.org/PathwayBrowser/#/R-HSA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc TAS Homo sapiens 58189 R-HSA-5694409 https://reactome.org/PathwayBrowser/#/R-HSA-5694409 Nucleotide exchange on RAB1 TAS Homo sapiens 58189 R-HSA-5694439 https://reactome.org/PathwayBrowser/#/R-HSA-5694439 COPII coat binds TRAPPCII and RAB1:GDP TAS Homo sapiens 58189 R-HSA-5694527 https://reactome.org/PathwayBrowser/#/R-HSA-5694527 Loss of SAR1B GTPase TAS Homo sapiens 58189 R-HSA-6783483 https://reactome.org/PathwayBrowser/#/R-HSA-6783483 tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol TAS Homo sapiens 58189 R-HSA-6788611 https://reactome.org/PathwayBrowser/#/R-HSA-6788611 HYKK phosphorylates 5HLYS TAS Homo sapiens 58189 R-HSA-6807866 https://reactome.org/PathwayBrowser/#/R-HSA-6807866 GBF1 recruits ARF:GDP to the ERGIC TAS Homo sapiens 58189 R-HSA-6807868 https://reactome.org/PathwayBrowser/#/R-HSA-6807868 GBF1 stimulates ARF nucleotide exchange TAS Homo sapiens 58189 R-HSA-6807877 https://reactome.org/PathwayBrowser/#/R-HSA-6807877 ARFGAPs stimulate ARF GTPase activity TAS Homo sapiens 58189 R-HSA-6809003 https://reactome.org/PathwayBrowser/#/R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin TAS Homo sapiens 58189 R-HSA-6809006 https://reactome.org/PathwayBrowser/#/R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex TAS Homo sapiens 58189 R-HSA-6809010 https://reactome.org/PathwayBrowser/#/R-HSA-6809010 COPI vesicle uncoating TAS Homo sapiens 58189 R-HSA-6811411 https://reactome.org/PathwayBrowser/#/R-HSA-6811411 GBF1 recruits ARF:GDP to the Golgi TAS Homo sapiens 58189 R-HSA-6811414 https://reactome.org/PathwayBrowser/#/R-HSA-6811414 GBF1 stimulates nucleotide exchange on ARF TAS Homo sapiens 58189 R-HSA-6811418 https://reactome.org/PathwayBrowser/#/R-HSA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane TAS Homo sapiens 58189 R-HSA-6811423 https://reactome.org/PathwayBrowser/#/R-HSA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs TAS Homo sapiens 58189 R-HSA-6811426 https://reactome.org/PathwayBrowser/#/R-HSA-6811426 Retrograde COPI vesicles bind kinesin and microtubules TAS Homo sapiens 58189 R-HSA-6811427 https://reactome.org/PathwayBrowser/#/R-HSA-6811427 COPI vesicle uncoating at the ER TAS Homo sapiens 58189 R-HSA-6811428 https://reactome.org/PathwayBrowser/#/R-HSA-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN TAS Homo sapiens 58189 R-HSA-6811429 https://reactome.org/PathwayBrowser/#/R-HSA-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange TAS Homo sapiens 58189 R-HSA-6814671 https://reactome.org/PathwayBrowser/#/R-HSA-6814671 Fusion of late-endosome derived vesicles at the TGN TAS Homo sapiens 58189 R-HSA-6814682 https://reactome.org/PathwayBrowser/#/R-HSA-6814682 Fusion of early-endosome derived vesicles at the TGN TAS Homo sapiens 58189 R-HSA-6814833 https://reactome.org/PathwayBrowser/#/R-HSA-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP TAS Homo sapiens 58189 R-HSA-70241 https://reactome.org/PathwayBrowser/#/R-HSA-70241 PCK1 phosphorylates OA to yield PEP TAS Homo sapiens 58189 R-HSA-71775 https://reactome.org/PathwayBrowser/#/R-HSA-71775 SUCLG1/G2 cleaves succinyl-CoA TAS Homo sapiens 58189 R-HSA-72619 https://reactome.org/PathwayBrowser/#/R-HSA-72619 eIF2:GTP is hydrolyzed, eIFs are released TAS Homo sapiens 58189 R-HSA-72670 https://reactome.org/PathwayBrowser/#/R-HSA-72670 Formation of eIF2:GDP:eIF2B intermediate TAS Homo sapiens 58189 R-HSA-72671 https://reactome.org/PathwayBrowser/#/R-HSA-72671 eIF5B:GTP is hydrolyzed and released TAS Homo sapiens 58189 R-HSA-72722 https://reactome.org/PathwayBrowser/#/R-HSA-72722 eIF2 activation TAS Homo sapiens 58189 R-HSA-73788 https://reactome.org/PathwayBrowser/#/R-HSA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) TAS Homo sapiens 58189 R-HSA-74065 https://reactome.org/PathwayBrowser/#/R-HSA-74065 GNAT1-GTP binds PDE6 and activates it IEA Homo sapiens 58189 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 58189 R-HSA-74882 https://reactome.org/PathwayBrowser/#/R-HSA-74882 GNAT1-GDP binds to GNB1:GNGT1 IEA Homo sapiens 58189 R-HSA-749453 https://reactome.org/PathwayBrowser/#/R-HSA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz TAS Homo sapiens 58189 R-HSA-751013 https://reactome.org/PathwayBrowser/#/R-HSA-751013 Inactive G alpha (s) reassociates with G beta:gamma TAS Homo sapiens 58189 R-HSA-751029 https://reactome.org/PathwayBrowser/#/R-HSA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 TAS Homo sapiens 58189 R-HSA-825631 https://reactome.org/PathwayBrowser/#/R-HSA-825631 Glucagon:GCGR mediates GTP-GDP exchange TAS Homo sapiens 58189 R-HSA-8847534 https://reactome.org/PathwayBrowser/#/R-HSA-8847534 RAB43 hydrolyses GTP TAS Homo sapiens 58189 R-HSA-8847883 https://reactome.org/PathwayBrowser/#/R-HSA-8847883 CYTH proteins stimulate ARF1 GTPase activity TAS Homo sapiens 58189 R-HSA-8848618 https://reactome.org/PathwayBrowser/#/R-HSA-8848618 Activation of RAC1 by the PXN:CRK complex TAS Homo sapiens 58189 R-HSA-8849082 https://reactome.org/PathwayBrowser/#/R-HSA-8849082 ARHGAP35 stimulates RHOA GTPase activity TAS Homo sapiens 58189 R-HSA-8849350 https://reactome.org/PathwayBrowser/#/R-HSA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex TAS Homo sapiens 58189 R-HSA-8849353 https://reactome.org/PathwayBrowser/#/R-HSA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER TAS Homo sapiens 58189 R-HSA-8850040 https://reactome.org/PathwayBrowser/#/R-HSA-8850040 RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER TAS Homo sapiens 58189 R-HSA-8850041 https://reactome.org/PathwayBrowser/#/R-HSA-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 TAS Homo sapiens 58189 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58189 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58189 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58189 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58189 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58189 R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58189 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58189 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58189 R-HSA-8851827 https://reactome.org/PathwayBrowser/#/R-HSA-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 TAS Homo sapiens 58189 R-HSA-8851877 https://reactome.org/PathwayBrowser/#/R-HSA-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET TAS Homo sapiens 58189 R-HSA-8851899 https://reactome.org/PathwayBrowser/#/R-HSA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET TAS Homo sapiens 58189 R-HSA-8852280 https://reactome.org/PathwayBrowser/#/R-HSA-8852280 GTSE1 binds microtubule lattice in interphase cells TAS Homo sapiens 58189 R-HSA-8852298 https://reactome.org/PathwayBrowser/#/R-HSA-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends TAS Homo sapiens 58189 R-HSA-8852306 https://reactome.org/PathwayBrowser/#/R-HSA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends TAS Homo sapiens 58189 R-HSA-8854173 https://reactome.org/PathwayBrowser/#/R-HSA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 TAS Homo sapiens 58189 R-HSA-8854255 https://reactome.org/PathwayBrowser/#/R-HSA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 58189 R-HSA-8854612 https://reactome.org/PathwayBrowser/#/R-HSA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B TAS Homo sapiens 58189 R-HSA-8865774 https://reactome.org/PathwayBrowser/#/R-HSA-8865774 TTLLs polyglutamylate tubulin TAS Homo sapiens 58189 R-HSA-8866105 https://reactome.org/PathwayBrowser/#/R-HSA-8866105 CCPs deglutamylate tubulin IEA Homo sapiens 58189 R-HSA-8867370 https://reactome.org/PathwayBrowser/#/R-HSA-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin TAS Homo sapiens 58189 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 58189 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 58189 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 58189 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 58189 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 58189 R-HSA-8870466 https://reactome.org/PathwayBrowser/#/R-HSA-8870466 RGGT:CHM binds RABs TAS Homo sapiens 58189 R-HSA-8870469 https://reactome.org/PathwayBrowser/#/R-HSA-8870469 RGGT geranylgeranylates RAB proteins TAS Homo sapiens 58189 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 58189 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 58189 R-HSA-8875318 https://reactome.org/PathwayBrowser/#/R-HSA-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A TAS Homo sapiens 58189 R-HSA-8875320 https://reactome.org/PathwayBrowser/#/R-HSA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 TAS Homo sapiens 58189 R-HSA-8875568 https://reactome.org/PathwayBrowser/#/R-HSA-8875568 RAPGEF1 activates RAP1 TAS Homo sapiens 58189 R-HSA-8875591 https://reactome.org/PathwayBrowser/#/R-HSA-8875591 DOCK7 activates RAC1 TAS Homo sapiens 58189 R-HSA-8876188 https://reactome.org/PathwayBrowser/#/R-HSA-8876188 DENND4s exchange GTP for GDP on RAB10 TAS Homo sapiens 58189 R-HSA-8876190 https://reactome.org/PathwayBrowser/#/R-HSA-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 TAS Homo sapiens 58189 R-HSA-8876191 https://reactome.org/PathwayBrowser/#/R-HSA-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 TAS Homo sapiens 58189 R-HSA-8876193 https://reactome.org/PathwayBrowser/#/R-HSA-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 TAS Homo sapiens 58189 R-HSA-8876454 https://reactome.org/PathwayBrowser/#/R-HSA-8876454 DENND3 exchanges GTP for GDP on RAB12 TAS Homo sapiens 58189 R-HSA-8876615 https://reactome.org/PathwayBrowser/#/R-HSA-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 TAS Homo sapiens 58189 R-HSA-8876616 https://reactome.org/PathwayBrowser/#/R-HSA-8876616 DENND6A,B exchange GTP for GDP on RAB14 TAS Homo sapiens 58189 R-HSA-8876837 https://reactome.org/PathwayBrowser/#/R-HSA-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 TAS Homo sapiens 58189 R-HSA-8877308 https://reactome.org/PathwayBrowser/#/R-HSA-8877308 MADD exchanges GTP for GDP on RAB27 TAS Homo sapiens 58189 R-HSA-8877311 https://reactome.org/PathwayBrowser/#/R-HSA-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 TAS Homo sapiens 58189 R-HSA-8877451 https://reactome.org/PathwayBrowser/#/R-HSA-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 TAS Homo sapiens 58189 R-HSA-8877475 https://reactome.org/PathwayBrowser/#/R-HSA-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 TAS Homo sapiens 58189 R-HSA-8877612 https://reactome.org/PathwayBrowser/#/R-HSA-8877612 DENND1s exchange GTP for GDP on RAB35 TAS Homo sapiens 58189 R-HSA-8877760 https://reactome.org/PathwayBrowser/#/R-HSA-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 TAS Homo sapiens 58189 R-HSA-8877813 https://reactome.org/PathwayBrowser/#/R-HSA-8877813 DENND5A,B exchange GTP for GDP on RAB39 TAS Homo sapiens 58189 R-HSA-8877998 https://reactome.org/PathwayBrowser/#/R-HSA-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 TAS Homo sapiens 58189 R-HSA-8938815 https://reactome.org/PathwayBrowser/#/R-HSA-8938815 RNF152 polyubiquitinates RRAGA TAS Homo sapiens 58189 R-HSA-8938829 https://reactome.org/PathwayBrowser/#/R-HSA-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 TAS Homo sapiens 58189 R-HSA-8941613 https://reactome.org/PathwayBrowser/#/R-HSA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-8941618 https://reactome.org/PathwayBrowser/#/R-HSA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-8941623 https://reactome.org/PathwayBrowser/#/R-HSA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-8941628 https://reactome.org/PathwayBrowser/#/R-HSA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange TAS Homo sapiens 58189 R-HSA-8944454 https://reactome.org/PathwayBrowser/#/R-HSA-8944454 mTORC1 phosphorylates MAF1 TAS Homo sapiens 58189 R-HSA-8944457 https://reactome.org/PathwayBrowser/#/R-HSA-8944457 MAF1 translocates to the nucleus TAS Homo sapiens 58189 R-HSA-8951498 https://reactome.org/PathwayBrowser/#/R-HSA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex TAS Homo sapiens 58189 R-HSA-8951586 https://reactome.org/PathwayBrowser/#/R-HSA-8951586 p-VAV family:PIP3 binds RAC1:GDP TAS Homo sapiens 58189 R-HSA-8952716 https://reactome.org/PathwayBrowser/#/R-HSA-8952716 SLC38A9 binds Ragulator:Rag dimers TAS Homo sapiens 58189 R-HSA-8952726 https://reactome.org/PathwayBrowser/#/R-HSA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol TAS Homo sapiens 58189 R-HSA-8955706 https://reactome.org/PathwayBrowser/#/R-HSA-8955706 TTL ligates L-Tyr to the carboxy terminus of detyr-alpha tubulin:beta tubulin IEA Homo sapiens 58189 R-HSA-8955712 https://reactome.org/PathwayBrowser/#/R-HSA-8955712 SVBP:VASH1,VASH2 hydrolyzes the terminal L-Tyr residue from alphaY-beta tubulin dimer IEA Homo sapiens 58189 R-HSA-8955869 https://reactome.org/PathwayBrowser/#/R-HSA-8955869 Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin IEA Homo sapiens 58189 R-HSA-8980691 https://reactome.org/PathwayBrowser/#/R-HSA-8980691 RHOA GEFs activate RHOA TAS Homo sapiens 58189 R-HSA-8981353 https://reactome.org/PathwayBrowser/#/R-HSA-8981353 RASA1 stimulates RAS GTPase activity TAS Homo sapiens 58189 R-HSA-8981637 https://reactome.org/PathwayBrowser/#/R-HSA-8981637 RHOA GAPs stimulate RHOA GTPase activity TAS Homo sapiens 58189 R-HSA-8982012 https://reactome.org/PathwayBrowser/#/R-HSA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 TAS Homo sapiens 58189 R-HSA-8982018 https://reactome.org/PathwayBrowser/#/R-HSA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) TAS Homo sapiens 58189 R-HSA-8982020 https://reactome.org/PathwayBrowser/#/R-HSA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated TAS Homo sapiens 58189 R-HSA-8982021 https://reactome.org/PathwayBrowser/#/R-HSA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated TAS Homo sapiens 58189 R-HSA-8982025 https://reactome.org/PathwayBrowser/#/R-HSA-8982025 G alpha (q) in G (q):RGS complex is inactivated TAS Homo sapiens 58189 R-HSA-8982026 https://reactome.org/PathwayBrowser/#/R-HSA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) TAS Homo sapiens 58189 R-HSA-8985594 https://reactome.org/PathwayBrowser/#/R-HSA-8985594 MYO9B inactivates RHOA TAS Homo sapiens 58189 R-HSA-9012761 https://reactome.org/PathwayBrowser/#/R-HSA-9012761 The p75NTR:NgR:MDGI binds RHOA-GDI TAS Homo sapiens 58189 R-HSA-9012835 https://reactome.org/PathwayBrowser/#/R-HSA-9012835 GDIs block activation of RHOA TAS Homo sapiens 58189 R-HSA-9013021 https://reactome.org/PathwayBrowser/#/R-HSA-9013021 GDIs block activation of RHOB TAS Homo sapiens 58189 R-HSA-9013022 https://reactome.org/PathwayBrowser/#/R-HSA-9013022 RHOB GAPs stimulate RHOB GTPase activity TAS Homo sapiens 58189 R-HSA-9013023 https://reactome.org/PathwayBrowser/#/R-HSA-9013023 RHOB GEFs activate RHOB TAS Homo sapiens 58189 R-HSA-9013108 https://reactome.org/PathwayBrowser/#/R-HSA-9013108 GDIs block activation of RHOC TAS Homo sapiens 58189 R-HSA-9013109 https://reactome.org/PathwayBrowser/#/R-HSA-9013109 RHOC GEFs activate RHOC TAS Homo sapiens 58189 R-HSA-9013111 https://reactome.org/PathwayBrowser/#/R-HSA-9013111 RHOC GAPs stimulate RHOC GTPase activity TAS Homo sapiens 58189 R-HSA-9013143 https://reactome.org/PathwayBrowser/#/R-HSA-9013143 RAC1 GEFs activate RAC1 TAS Homo sapiens 58189 R-HSA-9013144 https://reactome.org/PathwayBrowser/#/R-HSA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity TAS Homo sapiens 58189 R-HSA-9013147 https://reactome.org/PathwayBrowser/#/R-HSA-9013147 RAC1 GDIs block activation of RAC1 TAS Homo sapiens 58189 R-HSA-9013158 https://reactome.org/PathwayBrowser/#/R-HSA-9013158 CDC42 GDIs block activation of CDC42 TAS Homo sapiens 58189 R-HSA-9013159 https://reactome.org/PathwayBrowser/#/R-HSA-9013159 CDC42 GEFs activate CDC42 TAS Homo sapiens 58189 R-HSA-9013161 https://reactome.org/PathwayBrowser/#/R-HSA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity TAS Homo sapiens 58189 R-HSA-9013435 https://reactome.org/PathwayBrowser/#/R-HSA-9013435 RHOD auto-activates TAS Homo sapiens 58189 R-HSA-9013437 https://reactome.org/PathwayBrowser/#/R-HSA-9013437 RHOD GAPs stimulate RHOD GTPase activity TAS Homo sapiens 58189 R-HSA-9014293 https://reactome.org/PathwayBrowser/#/R-HSA-9014293 RAC2 GDIs block activation of RAC2 TAS Homo sapiens 58189 R-HSA-9014295 https://reactome.org/PathwayBrowser/#/R-HSA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity TAS Homo sapiens 58189 R-HSA-9014296 https://reactome.org/PathwayBrowser/#/R-HSA-9014296 RAC2 GEFs activate RAC2 TAS Homo sapiens 58189 R-HSA-9014433 https://reactome.org/PathwayBrowser/#/R-HSA-9014433 RHOG GEFs activate RHOG TAS Homo sapiens 58189 R-HSA-9014434 https://reactome.org/PathwayBrowser/#/R-HSA-9014434 RHOG GAPs stimulate RHOG GTPase activity TAS Homo sapiens 58189 R-HSA-9014456 https://reactome.org/PathwayBrowser/#/R-HSA-9014456 GDIs block activation of RHOG TAS Homo sapiens 58189 R-HSA-9014610 https://reactome.org/PathwayBrowser/#/R-HSA-9014610 Translation of ROBO3.2 mRNA initiates NMD IEA Homo sapiens 58189 R-HSA-9014652 https://reactome.org/PathwayBrowser/#/R-HSA-9014652 Translation of ROBO3.2 mRNA is negatively regulated by NMD IEA Homo sapiens 58189 R-HSA-9017488 https://reactome.org/PathwayBrowser/#/R-HSA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity TAS Homo sapiens 58189 R-HSA-9017491 https://reactome.org/PathwayBrowser/#/R-HSA-9017491 RHOJ GEFs activate RHOJ TAS Homo sapiens 58189 R-HSA-9018745 https://reactome.org/PathwayBrowser/#/R-HSA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity TAS Homo sapiens 58189 R-HSA-9018747 https://reactome.org/PathwayBrowser/#/R-HSA-9018747 RHOQ GEFs activate RHOQ TAS Homo sapiens 58189 R-HSA-9018768 https://reactome.org/PathwayBrowser/#/R-HSA-9018768 RHOU auto-activates TAS Homo sapiens 58189 R-HSA-9018798 https://reactome.org/PathwayBrowser/#/R-HSA-9018798 RHOV binds GTP TAS Homo sapiens 58189 R-HSA-9018804 https://reactome.org/PathwayBrowser/#/R-HSA-9018804 RAC3 GEFs activate RAC3 TAS Homo sapiens 58189 R-HSA-9018806 https://reactome.org/PathwayBrowser/#/R-HSA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity TAS Homo sapiens 58189 R-HSA-9018807 https://reactome.org/PathwayBrowser/#/R-HSA-9018807 RAC3 GDIs block activation of RAC3 TAS Homo sapiens 58189 R-HSA-9018814 https://reactome.org/PathwayBrowser/#/R-HSA-9018814 RHOT1 hydrolyzes GTP TAS Homo sapiens 58189 R-HSA-9018817 https://reactome.org/PathwayBrowser/#/R-HSA-9018817 RHOT1 GEFs activate RHOT1 IEA Homo sapiens 58189 R-HSA-9018825 https://reactome.org/PathwayBrowser/#/R-HSA-9018825 RHOT2 GEFs activate RHOT2 IEA Homo sapiens 58189 R-HSA-9018826 https://reactome.org/PathwayBrowser/#/R-HSA-9018826 RHOT2 hydrolyzes GTP TAS Homo sapiens 58189 R-HSA-9026891 https://reactome.org/PathwayBrowser/#/R-HSA-9026891 NTRK2 activates RAS signaling through SHC1 IEA Homo sapiens 58189 R-HSA-9029158 https://reactome.org/PathwayBrowser/#/R-HSA-9029158 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:GRB2-1:SOS1,phospho-VAV1 mediates exchange of GTP for GDP bound to RAS IEA Homo sapiens 58189 R-HSA-9032067 https://reactome.org/PathwayBrowser/#/R-HSA-9032067 NTRK2 activates RAS signaling through FRS2 IEA Homo sapiens 58189 R-HSA-9032798 https://reactome.org/PathwayBrowser/#/R-HSA-9032798 DOCK3 activates RAC1 TAS Homo sapiens 58189 R-HSA-9033292 https://reactome.org/PathwayBrowser/#/R-HSA-9033292 NTRK2 and CDK5 promote activation of RAC1 by TIAM1 IEA Homo sapiens 58189 R-HSA-9033949 https://reactome.org/PathwayBrowser/#/R-HSA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC TAS Homo sapiens 58189 R-HSA-9036301 https://reactome.org/PathwayBrowser/#/R-HSA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s TAS Homo sapiens 58189 R-HSA-9036307 https://reactome.org/PathwayBrowser/#/R-HSA-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG TAS Homo sapiens 58189 R-HSA-9036970 https://reactome.org/PathwayBrowser/#/R-HSA-9036970 NTRK3 activates RAS through SHC1 IEA Homo sapiens 58189 R-HSA-9036987 https://reactome.org/PathwayBrowser/#/R-HSA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec TAS Homo sapiens 58189 R-HSA-927789 https://reactome.org/PathwayBrowser/#/R-HSA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex TAS Homo sapiens 58189 R-HSA-927813 https://reactome.org/PathwayBrowser/#/R-HSA-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A TAS Homo sapiens 58189 R-HSA-927832 https://reactome.org/PathwayBrowser/#/R-HSA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex TAS Homo sapiens 58189 R-HSA-927836 https://reactome.org/PathwayBrowser/#/R-HSA-927836 SMG6 hydrolyzes mRNA with premature termination codon TAS Homo sapiens 58189 R-HSA-927889 https://reactome.org/PathwayBrowser/#/R-HSA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) TAS Homo sapiens 58189 R-HSA-939265 https://reactome.org/PathwayBrowser/#/R-HSA-939265 Activation of Rap1 by membrane-associated GEFs TAS Homo sapiens 58189 R-HSA-9603982 https://reactome.org/PathwayBrowser/#/R-HSA-9603982 FUT2 transfers Fuc to LeA to form LeB TAS Homo sapiens 58189 R-HSA-9603983 https://reactome.org/PathwayBrowser/#/R-HSA-9603983 FUT2 transfers Fuc to LeX to form LeY TAS Homo sapiens 58189 R-HSA-9603984 https://reactome.org/PathwayBrowser/#/R-HSA-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX TAS Homo sapiens 58189 R-HSA-9603986 https://reactome.org/PathwayBrowser/#/R-HSA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA TAS Homo sapiens 58189 R-HSA-9605609 https://reactome.org/PathwayBrowser/#/R-HSA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA TAS Homo sapiens 58189 R-HSA-9605644 https://reactome.org/PathwayBrowser/#/R-HSA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA TAS Homo sapiens 58189 R-HSA-9605682 https://reactome.org/PathwayBrowser/#/R-HSA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX TAS Homo sapiens 58189 R-HSA-9607304 https://reactome.org/PathwayBrowser/#/R-HSA-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 TAS Homo sapiens 58189 R-HSA-9610408 https://reactome.org/PathwayBrowser/#/R-HSA-9610408 GluN1:GluN2B (GRIN1:GRIN2B) di-heterotetramers bind LIN7:CASK:APBA1, DLG1 and KIF17 IEA Homo sapiens 58189 R-HSA-9610627 https://reactome.org/PathwayBrowser/#/R-HSA-9610627 KIF17 transports GluN1:GluN2B (GRIN1:GRIN2B) NMDA receptors to the plasma membrane IEA Homo sapiens 58189 R-HSA-9614343 https://reactome.org/PathwayBrowser/#/R-HSA-9614343 Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs TAS Homo sapiens 58189 R-HSA-9614367 https://reactome.org/PathwayBrowser/#/R-HSA-9614367 HCMV Nuclear Pore Docking TAS Homo sapiens 58189 R-HSA-9619542 https://reactome.org/PathwayBrowser/#/R-HSA-9619542 AMPK negatively regulates binding of MAPT to microtubules IEA Homo sapiens 58189 R-HSA-9619803 https://reactome.org/PathwayBrowser/#/R-HSA-9619803 p-S516-ARHGEF7 activates RAC1 IEA Homo sapiens 58189 R-HSA-9624845 https://reactome.org/PathwayBrowser/#/R-HSA-9624845 RCC1 stimulates GDP to GTP exchange on RAN TAS Homo sapiens 58189 R-HSA-9624893 https://reactome.org/PathwayBrowser/#/R-HSA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes TAS Homo sapiens 58189 R-HSA-9632906 https://reactome.org/PathwayBrowser/#/R-HSA-9632906 PRKCZ recruits RAS in response to estrogen stimulation TAS Homo sapiens 58189 R-HSA-9632918 https://reactome.org/PathwayBrowser/#/R-HSA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen TAS Homo sapiens 58189 R-HSA-9634418 https://reactome.org/PathwayBrowser/#/R-HSA-9634418 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and ERBB2 homodimer:p-SHC1 TAS Homo sapiens 58189 R-HSA-9636684 https://reactome.org/PathwayBrowser/#/R-HSA-9636684 ndkA dephosphorylates RAB5A:GTP,RAB7A:GTP TAS Homo sapiens 58189 R-HSA-9639286 https://reactome.org/PathwayBrowser/#/R-HSA-9639286 RRAGC,D exchanges GTP for GDP TAS Homo sapiens 58189 R-HSA-9640167 https://reactome.org/PathwayBrowser/#/R-HSA-9640167 RRAGA,B exchanges GDP for GTP TAS Homo sapiens 58189 R-HSA-9640168 https://reactome.org/PathwayBrowser/#/R-HSA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine TAS Homo sapiens 58189 R-HSA-9640175 https://reactome.org/PathwayBrowser/#/R-HSA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine TAS Homo sapiens 58189 R-HSA-9640195 https://reactome.org/PathwayBrowser/#/R-HSA-9640195 RRAGA,B hydrolyzes GTP TAS Homo sapiens 58189 R-HSA-9645598 https://reactome.org/PathwayBrowser/#/R-HSA-9645598 RRAGC,D hydrolyzes GTP TAS Homo sapiens 58189 R-HSA-9645608 https://reactome.org/PathwayBrowser/#/R-HSA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 TAS Homo sapiens 58189 R-HSA-9646383 https://reactome.org/PathwayBrowser/#/R-HSA-9646383 Dynein motors transport misfolded proteins IEA Homo sapiens 58189 R-HSA-9646390 https://reactome.org/PathwayBrowser/#/R-HSA-9646390 Misfolded proteins:HDAC6:Dynein motor binds microtubule IEA Homo sapiens 58189 R-HSA-9646468 https://reactome.org/PathwayBrowser/#/R-HSA-9646468 mTORC1 binds RHEB:GTP TAS Homo sapiens 58189 R-HSA-9646679 https://reactome.org/PathwayBrowser/#/R-HSA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome TAS Homo sapiens 58189 R-HSA-9646685 https://reactome.org/PathwayBrowser/#/R-HSA-9646685 Aggresome dissociates from dynein and microtubule TAS Homo sapiens 58189 R-HSA-9648017 https://reactome.org/PathwayBrowser/#/R-HSA-9648017 EML4 binds to microtubules TAS Homo sapiens 58189 R-HSA-9648114 https://reactome.org/PathwayBrowser/#/R-HSA-9648114 EML4 recruits NUDC to mitotic spindle TAS Homo sapiens 58189 R-HSA-9649733 https://reactome.org/PathwayBrowser/#/R-HSA-9649733 mature p21 RAS binds GDP TAS Homo sapiens 58189 R-HSA-9649735 https://reactome.org/PathwayBrowser/#/R-HSA-9649735 Intrinsic nucleotide exchange on RAS TAS Homo sapiens 58189 R-HSA-9649736 https://reactome.org/PathwayBrowser/#/R-HSA-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP TAS Homo sapiens 58189 R-HSA-9660824 https://reactome.org/PathwayBrowser/#/R-HSA-9660824 ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs TAS Homo sapiens 58189 R-HSA-9660828 https://reactome.org/PathwayBrowser/#/R-HSA-9660828 ADORA2B:Ade-Rib binds heterometric G-protein Gs TAS Homo sapiens 58189 R-HSA-9664991 https://reactome.org/PathwayBrowser/#/R-HSA-9664991 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants TAS Homo sapiens 58189 R-HSA-9665009 https://reactome.org/PathwayBrowser/#/R-HSA-9665009 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR TAS Homo sapiens 58189 R-HSA-9665404 https://reactome.org/PathwayBrowser/#/R-HSA-9665404 RAS guanyl nucleotide exchange mediated by the p-6Y- ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-SHC1:GRB2:SOS1 TAS Homo sapiens 58189 R-HSA-9665408 https://reactome.org/PathwayBrowser/#/R-HSA-9665408 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR through GRB2 TAS Homo sapiens 58189 R-HSA-9665700 https://reactome.org/PathwayBrowser/#/R-HSA-9665700 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants TAS Homo sapiens 58189 R-HSA-9665707 https://reactome.org/PathwayBrowser/#/R-HSA-9665707 RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR TAS Homo sapiens 58189 R-HSA-9666428 https://reactome.org/PathwayBrowser/#/R-HSA-9666428 DOCK180 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens 58189 R-HSA-9666430 https://reactome.org/PathwayBrowser/#/R-HSA-9666430 p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens 58189 R-HSA-9668419 https://reactome.org/PathwayBrowser/#/R-HSA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites TAS Homo sapiens 58189 R-HSA-9670436 https://reactome.org/PathwayBrowser/#/R-HSA-9670436 p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS TAS Homo sapiens 58189 R-HSA-9672163 https://reactome.org/PathwayBrowser/#/R-HSA-9672163 SOS-mediated nucleotide exchange on RAS downstream of PDGFRA extracellular domain dimers TAS Homo sapiens 58189 R-HSA-9672170 https://reactome.org/PathwayBrowser/#/R-HSA-9672170 SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors TAS Homo sapiens 58189 R-HSA-9680385 https://reactome.org/PathwayBrowser/#/R-HSA-9680385 CSF1R-associated SOS1 mediates exchange of GTP for GDP bound to RAS IEA Homo sapiens 58189 R-HSA-9693111 https://reactome.org/PathwayBrowser/#/R-HSA-9693111 RHOF auto-activates TAS Homo sapiens 58189 R-HSA-9693282 https://reactome.org/PathwayBrowser/#/R-HSA-9693282 RHOF GAPs stimulate RHOF GTPase activity TAS Homo sapiens 58189 R-HSA-9695853 https://reactome.org/PathwayBrowser/#/R-HSA-9695853 FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS TAS Homo sapiens 58189 R-HSA-9703441 https://reactome.org/PathwayBrowser/#/R-HSA-9703441 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 fusion mutants TAS Homo sapiens 58189 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 58189 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 58189 R-HSA-9717202 https://reactome.org/PathwayBrowser/#/R-HSA-9717202 GNAT3 exchanges GDP for GTP in L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 58189 R-HSA-9717206 https://reactome.org/PathwayBrowser/#/R-HSA-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) TAS Homo sapiens 58189 R-HSA-9726848 https://reactome.org/PathwayBrowser/#/R-HSA-9726848 SRC phosphorylates RHOU IEA Homo sapiens 58189 R-HSA-9726862 https://reactome.org/PathwayBrowser/#/R-HSA-9726862 Phosphorylated RHOU translocates to the endosome membrane TAS Homo sapiens 58189 R-HSA-9728664 https://reactome.org/PathwayBrowser/#/R-HSA-9728664 GLP1R binds GLP1R agonists TAS Homo sapiens 58189 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 58189 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 58189 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 58189 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 58189 R-HSA-9751201 https://reactome.org/PathwayBrowser/#/R-HSA-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 TAS Homo sapiens 58189 R-HSA-983259 https://reactome.org/PathwayBrowser/#/R-HSA-983259 Kinesins move along microtubules consuming ATP TAS Homo sapiens 58189 R-HSA-983266 https://reactome.org/PathwayBrowser/#/R-HSA-983266 Kinesins bind microtubules TAS Homo sapiens 58189 R-HSA-983422 https://reactome.org/PathwayBrowser/#/R-HSA-983422 Disassembly of COPII coated vesicle TAS Homo sapiens 58189 R-HSA-9836404 https://reactome.org/PathwayBrowser/#/R-HSA-9836404 p-PKR dimer phosphorylates MAPT TAS Homo sapiens 58189 R-HSA-9846332 https://reactome.org/PathwayBrowser/#/R-HSA-9846332 FUT1,2 transfer fucose to gangliosides TAS Homo sapiens 58189 R-MMU-1008248 https://reactome.org/PathwayBrowser/#/R-MMU-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Mus musculus 58189 R-MMU-1028788 https://reactome.org/PathwayBrowser/#/R-MMU-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Mus musculus 58189 R-MMU-110133 https://reactome.org/PathwayBrowser/#/R-MMU-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Mus musculus 58189 R-MMU-111519 https://reactome.org/PathwayBrowser/#/R-MMU-111519 inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate TAS Mus musculus 58189 R-MMU-111524 https://reactome.org/PathwayBrowser/#/R-MMU-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Mus musculus 58189 R-MMU-112037 https://reactome.org/PathwayBrowser/#/R-MMU-112037 Inactivation of PLC beta IEA Mus musculus 58189 R-MMU-114544 https://reactome.org/PathwayBrowser/#/R-MMU-114544 p115-RhoGEF activation of RHOA IEA Mus musculus 58189 R-MMU-114552 https://reactome.org/PathwayBrowser/#/R-MMU-114552 Thrombin-activated PARs activate G12/13 IEA Mus musculus 58189 R-MMU-114558 https://reactome.org/PathwayBrowser/#/R-MMU-114558 Thrombin-activated PARs activate Gq IEA Mus musculus 58189 R-MMU-1168636 https://reactome.org/PathwayBrowser/#/R-MMU-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Mus musculus 58189 R-MMU-1250383 https://reactome.org/PathwayBrowser/#/R-MMU-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Mus musculus 58189 R-MMU-1306972 https://reactome.org/PathwayBrowser/#/R-MMU-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Mus musculus 58189 R-MMU-1433415 https://reactome.org/PathwayBrowser/#/R-MMU-1433415 Activation of RAC1 IEA Mus musculus 58189 R-MMU-1433471 https://reactome.org/PathwayBrowser/#/R-MMU-1433471 Activation of RAS by p-KIT bound SOS1 IEA Mus musculus 58189 R-MMU-1449633 https://reactome.org/PathwayBrowser/#/R-MMU-1449633 Rab8a/10/13/14 Hydrolyze GTP TAS Mus musculus 58189 R-MMU-156913 https://reactome.org/PathwayBrowser/#/R-MMU-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Mus musculus 58189 R-MMU-162721 https://reactome.org/PathwayBrowser/#/R-MMU-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Mus musculus 58189 R-MMU-1638803 https://reactome.org/PathwayBrowser/#/R-MMU-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Mus musculus 58189 R-MMU-1638821 https://reactome.org/PathwayBrowser/#/R-MMU-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Mus musculus 58189 R-MMU-165195 https://reactome.org/PathwayBrowser/#/R-MMU-165195 GTP loading by Rheb IEA Mus musculus 58189 R-MMU-165680 https://reactome.org/PathwayBrowser/#/R-MMU-165680 Formation of active mTORC1 complex IEA Mus musculus 58189 R-MMU-165692 https://reactome.org/PathwayBrowser/#/R-MMU-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Mus musculus 58189 R-MMU-165718 https://reactome.org/PathwayBrowser/#/R-MMU-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Mus musculus 58189 R-MMU-167408 https://reactome.org/PathwayBrowser/#/R-MMU-167408 The high affinity receptor complex binds to G-protein IEA Mus musculus 58189 R-MMU-167415 https://reactome.org/PathwayBrowser/#/R-MMU-167415 G-protein alpha subunit is inactivated IEA Mus musculus 58189 R-MMU-167419 https://reactome.org/PathwayBrowser/#/R-MMU-167419 The receptor:G-protein complex releases GDP IEA Mus musculus 58189 R-MMU-167433 https://reactome.org/PathwayBrowser/#/R-MMU-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Mus musculus 58189 R-MMU-169904 https://reactome.org/PathwayBrowser/#/R-MMU-169904 C3G stimulates nucleotide exchange on Rap1 IEA Mus musculus 58189 R-MMU-170026 https://reactome.org/PathwayBrowser/#/R-MMU-170026 Protons are translocated from the intermembrane space to the matrix IEA Mus musculus 58189 R-MMU-170666 https://reactome.org/PathwayBrowser/#/R-MMU-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Mus musculus 58189 R-MMU-170674 https://reactome.org/PathwayBrowser/#/R-MMU-170674 Dissociation of the Gi alpha:G olf complex IEA Mus musculus 58189 R-MMU-170677 https://reactome.org/PathwayBrowser/#/R-MMU-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Mus musculus 58189 R-MMU-170685 https://reactome.org/PathwayBrowser/#/R-MMU-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Mus musculus 58189 R-MMU-170686 https://reactome.org/PathwayBrowser/#/R-MMU-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Mus musculus 58189 R-MMU-177938 https://reactome.org/PathwayBrowser/#/R-MMU-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Mus musculus 58189 R-MMU-177945 https://reactome.org/PathwayBrowser/#/R-MMU-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Mus musculus 58189 R-MMU-186834 https://reactome.org/PathwayBrowser/#/R-MMU-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Mus musculus 58189 R-MMU-190520 https://reactome.org/PathwayBrowser/#/R-MMU-190520 Association of Golgi transport vesicles with microtubules IEA Mus musculus 58189 R-MMU-193646 https://reactome.org/PathwayBrowser/#/R-MMU-193646 NGF binding to p75NTR inactivates RHOA IEA Mus musculus 58189 R-MMU-193668 https://reactome.org/PathwayBrowser/#/R-MMU-193668 p75NTR and RHOA-GDI interact IEA Mus musculus 58189 R-MMU-193696 https://reactome.org/PathwayBrowser/#/R-MMU-193696 The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA IEA Mus musculus 58189 R-MMU-194518 https://reactome.org/PathwayBrowser/#/R-MMU-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Mus musculus 58189 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus 58189 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus 58189 R-MMU-203977 https://reactome.org/PathwayBrowser/#/R-MMU-203977 SAR1 Activation And Membrane Binding IEA Mus musculus 58189 R-MMU-205039 https://reactome.org/PathwayBrowser/#/R-MMU-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Mus musculus 58189 R-MMU-210977 https://reactome.org/PathwayBrowser/#/R-MMU-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Mus musculus 58189 R-MMU-2130641 https://reactome.org/PathwayBrowser/#/R-MMU-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Mus musculus 58189 R-MMU-2130725 https://reactome.org/PathwayBrowser/#/R-MMU-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Mus musculus 58189 R-MMU-2179407 https://reactome.org/PathwayBrowser/#/R-MMU-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Mus musculus 58189 R-MMU-2213248 https://reactome.org/PathwayBrowser/#/R-MMU-2213248 Transport of antigen loaded MHC II molecules to surface IEA Mus musculus 58189 R-MMU-2255341 https://reactome.org/PathwayBrowser/#/R-MMU-2255341 Rab8A/10/13/14 Exchange GDP for GTP TAS Mus musculus 58189 R-MMU-2316350 https://reactome.org/PathwayBrowser/#/R-MMU-2316350 Rab4a:GTP Activates Kif3 TAS Mus musculus 58189 R-MMU-2424476 https://reactome.org/PathwayBrowser/#/R-MMU-2424476 Activation of RAC1 by VAV2/3 IEA Mus musculus 58189 R-MMU-2424477 https://reactome.org/PathwayBrowser/#/R-MMU-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Mus musculus 58189 R-MMU-2467809 https://reactome.org/PathwayBrowser/#/R-MMU-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Mus musculus 58189 R-MMU-2467811 https://reactome.org/PathwayBrowser/#/R-MMU-2467811 Separation of sister chromatids IEA Mus musculus 58189 R-MMU-2468287 https://reactome.org/PathwayBrowser/#/R-MMU-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Mus musculus 58189 R-MMU-2484822 https://reactome.org/PathwayBrowser/#/R-MMU-2484822 Kinetochore assembly IEA Mus musculus 58189 R-MMU-2584246 https://reactome.org/PathwayBrowser/#/R-MMU-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Mus musculus 58189 R-MMU-2730840 https://reactome.org/PathwayBrowser/#/R-MMU-2730840 Activation of RAC1 by VAV IEA Mus musculus 58189 R-MMU-350769 https://reactome.org/PathwayBrowser/#/R-MMU-350769 trans-Golgi Network Coat Activation IEA Mus musculus 58189 R-MMU-354173 https://reactome.org/PathwayBrowser/#/R-MMU-354173 Activation of Rap1 by cytosolic GEFs IEA Mus musculus 58189 R-MMU-372819 https://reactome.org/PathwayBrowser/#/R-MMU-372819 PCK2 phosphorylates OA to yield PEP IEA Mus musculus 58189 R-MMU-375302 https://reactome.org/PathwayBrowser/#/R-MMU-375302 Kinetochore capture of astral microtubules IEA Mus musculus 58189 R-MMU-377186 https://reactome.org/PathwayBrowser/#/R-MMU-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Mus musculus 58189 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 58189 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 58189 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 58189 R-MMU-380316 https://reactome.org/PathwayBrowser/#/R-MMU-380316 Association of NuMA with microtubules IEA Mus musculus 58189 R-MMU-380979 https://reactome.org/PathwayBrowser/#/R-MMU-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Mus musculus 58189 R-MMU-381612 https://reactome.org/PathwayBrowser/#/R-MMU-381612 GLP1R binds GLP1 IEA Mus musculus 58189 R-MMU-381727 https://reactome.org/PathwayBrowser/#/R-MMU-381727 RAP1A exchanges GDP for GTP IEA Mus musculus 58189 R-MMU-389348 https://reactome.org/PathwayBrowser/#/R-MMU-389348 Activation of Rac1 by pVav1 IEA Mus musculus 58189 R-MMU-389350 https://reactome.org/PathwayBrowser/#/R-MMU-389350 Activation of Cdc42 by pVav1 IEA Mus musculus 58189 R-MMU-392054 https://reactome.org/PathwayBrowser/#/R-MMU-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Mus musculus 58189 R-MMU-392195 https://reactome.org/PathwayBrowser/#/R-MMU-392195 Gi activation by P2Y purinoceptor 12 IEA Mus musculus 58189 R-MMU-392513 https://reactome.org/PathwayBrowser/#/R-MMU-392513 Rap1 signal termination by Rap1GAPs IEA Mus musculus 58189 R-MMU-3928592 https://reactome.org/PathwayBrowser/#/R-MMU-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Mus musculus 58189 R-MMU-3928628 https://reactome.org/PathwayBrowser/#/R-MMU-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 58189 R-MMU-3928642 https://reactome.org/PathwayBrowser/#/R-MMU-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 58189 R-MMU-3928643 https://reactome.org/PathwayBrowser/#/R-MMU-3928643 Activation of CDC42 by intersectin-1 TAS Mus musculus 58189 R-MMU-3928651 https://reactome.org/PathwayBrowser/#/R-MMU-3928651 NGEF exchanges GTP for GDP on RHOA IEA Mus musculus 58189 R-MMU-392870 https://reactome.org/PathwayBrowser/#/R-MMU-392870 Gs activation by prostacyclin receptor IEA Mus musculus 58189 R-MMU-3965444 https://reactome.org/PathwayBrowser/#/R-MMU-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Mus musculus 58189 R-MMU-400092 https://reactome.org/PathwayBrowser/#/R-MMU-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Mus musculus 58189 R-MMU-4093336 https://reactome.org/PathwayBrowser/#/R-MMU-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 58189 R-MMU-4093339 https://reactome.org/PathwayBrowser/#/R-MMU-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Mus musculus 58189 R-MMU-416530 https://reactome.org/PathwayBrowser/#/R-MMU-416530 FFAR1:FFAR1 ligands activate Gq IEA Mus musculus 58189 R-MMU-416559 https://reactome.org/PathwayBrowser/#/R-MMU-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Mus musculus 58189 R-MMU-416588 https://reactome.org/PathwayBrowser/#/R-MMU-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Mus musculus 58189 R-MMU-418850 https://reactome.org/PathwayBrowser/#/R-MMU-418850 Activation of Cdc42 IEA Mus musculus 58189 R-MMU-418856 https://reactome.org/PathwayBrowser/#/R-MMU-418856 Activation of Rac1 IEA Mus musculus 58189 R-MMU-419166 https://reactome.org/PathwayBrowser/#/R-MMU-419166 GEFs activate RhoA,B,C IEA Mus musculus 58189 R-MMU-420883 https://reactome.org/PathwayBrowser/#/R-MMU-420883 Opsins act as GEFs for G alpha-t IEA Mus musculus 58189 R-MMU-421142 https://reactome.org/PathwayBrowser/#/R-MMU-421142 Inactivation of R-Ras by Sema3A-Plexin-A1 GAP activity TAS Mus musculus 58189 R-MMU-421147 https://reactome.org/PathwayBrowser/#/R-MMU-421147 Activation of Rac1 by FARP2 TAS Mus musculus 58189 R-MMU-421831 https://reactome.org/PathwayBrowser/#/R-MMU-421831 trans-Golgi Network Coat Assembly IEA Mus musculus 58189 R-MMU-421835 https://reactome.org/PathwayBrowser/#/R-MMU-421835 trans-Golgi Network Vesicle Scission IEA Mus musculus 58189 R-MMU-426547 https://reactome.org/PathwayBrowser/#/R-MMU-426547 Activation of Gq by Muscarinic Acetylcholine Receptor M3 TAS Mus musculus 58189 R-MMU-428750 https://reactome.org/PathwayBrowser/#/R-MMU-428750 Gq activation by TP receptor IEA Mus musculus 58189 R-MMU-428917 https://reactome.org/PathwayBrowser/#/R-MMU-428917 G13 activation by TP receptor IEA Mus musculus 58189 R-MMU-432195 https://reactome.org/PathwayBrowser/#/R-MMU-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Mus musculus 58189 R-MMU-432706 https://reactome.org/PathwayBrowser/#/R-MMU-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Mus musculus 58189 R-MMU-432707 https://reactome.org/PathwayBrowser/#/R-MMU-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Mus musculus 58189 R-MMU-442273 https://reactome.org/PathwayBrowser/#/R-MMU-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Mus musculus 58189 R-MMU-442291 https://reactome.org/PathwayBrowser/#/R-MMU-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Mus musculus 58189 R-MMU-442314 https://reactome.org/PathwayBrowser/#/R-MMU-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Mus musculus 58189 R-MMU-445064 https://reactome.org/PathwayBrowser/#/R-MMU-445064 Activation of Rac1 by VAV2 IEA Mus musculus 58189 R-MMU-445071 https://reactome.org/PathwayBrowser/#/R-MMU-445071 Reinsertion of L1 into the plasma membrane IEA Mus musculus 58189 R-MMU-446208 https://reactome.org/PathwayBrowser/#/R-MMU-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Mus musculus 58189 R-MMU-446218 https://reactome.org/PathwayBrowser/#/R-MMU-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Mus musculus 58189 R-MMU-447074 https://reactome.org/PathwayBrowser/#/R-MMU-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Mus musculus 58189 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 58189 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 58189 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 58189 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 58189 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 58189 R-MMU-5218839 https://reactome.org/PathwayBrowser/#/R-MMU-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Mus musculus 58189 R-MMU-5218850 https://reactome.org/PathwayBrowser/#/R-MMU-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 58189 R-MMU-5419271 https://reactome.org/PathwayBrowser/#/R-MMU-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Mus musculus 58189 R-MMU-5419273 https://reactome.org/PathwayBrowser/#/R-MMU-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Mus musculus 58189 R-MMU-555065 https://reactome.org/PathwayBrowser/#/R-MMU-555065 Formation of clathrin coated vesicle IEA Mus musculus 58189 R-MMU-5610733 https://reactome.org/PathwayBrowser/#/R-MMU-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Mus musculus 58189 R-MMU-5610767 https://reactome.org/PathwayBrowser/#/R-MMU-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Mus musculus 58189 R-MMU-5617816 https://reactome.org/PathwayBrowser/#/R-MMU-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Mus musculus 58189 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 58189 R-MMU-5618328 https://reactome.org/PathwayBrowser/#/R-MMU-5618328 ATAT acetylates microtubules IEA Mus musculus 58189 R-MMU-5618331 https://reactome.org/PathwayBrowser/#/R-MMU-5618331 HDAC6 deacetylates microtubules IEA Mus musculus 58189 R-MMU-5623508 https://reactome.org/PathwayBrowser/#/R-MMU-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Mus musculus 58189 R-MMU-5623513 https://reactome.org/PathwayBrowser/#/R-MMU-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Mus musculus 58189 R-MMU-5623519 https://reactome.org/PathwayBrowser/#/R-MMU-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Mus musculus 58189 R-MMU-5623521 https://reactome.org/PathwayBrowser/#/R-MMU-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Mus musculus 58189 R-MMU-5624949 https://reactome.org/PathwayBrowser/#/R-MMU-5624949 Assembly of the anterograde IFT train IEA Mus musculus 58189 R-MMU-5624952 https://reactome.org/PathwayBrowser/#/R-MMU-5624952 Assembly of the retrograde IFT train IEA Mus musculus 58189 R-MMU-5625416 https://reactome.org/PathwayBrowser/#/R-MMU-5625416 Anterograde IFT IEA Mus musculus 58189 R-MMU-5625421 https://reactome.org/PathwayBrowser/#/R-MMU-5625421 The anterograde IFT train dissociates IEA Mus musculus 58189 R-MMU-5625424 https://reactome.org/PathwayBrowser/#/R-MMU-5625424 The retrograde IFT train dissociates IEA Mus musculus 58189 R-MMU-5625426 https://reactome.org/PathwayBrowser/#/R-MMU-5625426 Retrograde IFT IEA Mus musculus 58189 R-MMU-5653957 https://reactome.org/PathwayBrowser/#/R-MMU-5653957 Rag dimer formation IEA Mus musculus 58189 R-MMU-5653968 https://reactome.org/PathwayBrowser/#/R-MMU-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Mus musculus 58189 R-MMU-5653974 https://reactome.org/PathwayBrowser/#/R-MMU-5653974 Ragulator binds Rag dimers IEA Mus musculus 58189 R-MMU-5654392 https://reactome.org/PathwayBrowser/#/R-MMU-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-5654402 https://reactome.org/PathwayBrowser/#/R-MMU-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-5654413 https://reactome.org/PathwayBrowser/#/R-MMU-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-5654426 https://reactome.org/PathwayBrowser/#/R-MMU-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-5654600 https://reactome.org/PathwayBrowser/#/R-MMU-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-5654618 https://reactome.org/PathwayBrowser/#/R-MMU-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-5654647 https://reactome.org/PathwayBrowser/#/R-MMU-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-5654663 https://reactome.org/PathwayBrowser/#/R-MMU-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-5658231 https://reactome.org/PathwayBrowser/#/R-MMU-5658231 RAS GAPs stimulate RAS GTPase activity IEA Mus musculus 58189 R-MMU-5665809 https://reactome.org/PathwayBrowser/#/R-MMU-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Mus musculus 58189 R-MMU-5666169 https://reactome.org/PathwayBrowser/#/R-MMU-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Mus musculus 58189 R-MMU-5672010 https://reactome.org/PathwayBrowser/#/R-MMU-5672010 Active MTORC1 phosphorylates ULK1 IEA Mus musculus 58189 R-MMU-5672017 https://reactome.org/PathwayBrowser/#/R-MMU-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Mus musculus 58189 R-MMU-5672329 https://reactome.org/PathwayBrowser/#/R-MMU-5672329 IQGAP1 binds CLIP1 and microtubules IEA Mus musculus 58189 R-MMU-5672817 https://reactome.org/PathwayBrowser/#/R-MMU-5672817 Active MTORC1 binds the ULK1 complex IEA Mus musculus 58189 R-MMU-5672824 https://reactome.org/PathwayBrowser/#/R-MMU-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Mus musculus 58189 R-MMU-5672828 https://reactome.org/PathwayBrowser/#/R-MMU-5672828 mTORC1 phosphorylates AKT1S1 IEA Mus musculus 58189 R-MMU-5672843 https://reactome.org/PathwayBrowser/#/R-MMU-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Mus musculus 58189 R-MMU-5672965 https://reactome.org/PathwayBrowser/#/R-MMU-5672965 RAS GEFs promote RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-5673768 https://reactome.org/PathwayBrowser/#/R-MMU-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Mus musculus 58189 R-MMU-5675790 https://reactome.org/PathwayBrowser/#/R-MMU-5675790 MTORC1 dissociates from ULK complex IEA Mus musculus 58189 R-MMU-5694409 https://reactome.org/PathwayBrowser/#/R-MMU-5694409 Nucleotide exchange on RAB1 IEA Mus musculus 58189 R-MMU-5694439 https://reactome.org/PathwayBrowser/#/R-MMU-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Mus musculus 58189 R-MMU-5694527 https://reactome.org/PathwayBrowser/#/R-MMU-5694527 Loss of SAR1B GTPase IEA Mus musculus 58189 R-MMU-6788611 https://reactome.org/PathwayBrowser/#/R-MMU-6788611 HYKK phosphorylates 5HLYS IEA Mus musculus 58189 R-MMU-6807866 https://reactome.org/PathwayBrowser/#/R-MMU-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Mus musculus 58189 R-MMU-6807868 https://reactome.org/PathwayBrowser/#/R-MMU-6807868 GBF1 stimulates ARF nucleotide exchange IEA Mus musculus 58189 R-MMU-6807877 https://reactome.org/PathwayBrowser/#/R-MMU-6807877 ARFGAPs stimulate ARF GTPase activity IEA Mus musculus 58189 R-MMU-6809003 https://reactome.org/PathwayBrowser/#/R-MMU-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Mus musculus 58189 R-MMU-6809006 https://reactome.org/PathwayBrowser/#/R-MMU-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Mus musculus 58189 R-MMU-6809010 https://reactome.org/PathwayBrowser/#/R-MMU-6809010 COPI vesicle uncoating IEA Mus musculus 58189 R-MMU-6811411 https://reactome.org/PathwayBrowser/#/R-MMU-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Mus musculus 58189 R-MMU-6811414 https://reactome.org/PathwayBrowser/#/R-MMU-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Mus musculus 58189 R-MMU-6811418 https://reactome.org/PathwayBrowser/#/R-MMU-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Mus musculus 58189 R-MMU-6811423 https://reactome.org/PathwayBrowser/#/R-MMU-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Mus musculus 58189 R-MMU-6811426 https://reactome.org/PathwayBrowser/#/R-MMU-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Mus musculus 58189 R-MMU-6811427 https://reactome.org/PathwayBrowser/#/R-MMU-6811427 COPI vesicle uncoating at the ER IEA Mus musculus 58189 R-MMU-6811428 https://reactome.org/PathwayBrowser/#/R-MMU-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Mus musculus 58189 R-MMU-6811429 https://reactome.org/PathwayBrowser/#/R-MMU-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Mus musculus 58189 R-MMU-6814671 https://reactome.org/PathwayBrowser/#/R-MMU-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Mus musculus 58189 R-MMU-6814682 https://reactome.org/PathwayBrowser/#/R-MMU-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Mus musculus 58189 R-MMU-6814833 https://reactome.org/PathwayBrowser/#/R-MMU-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Mus musculus 58189 R-MMU-70241 https://reactome.org/PathwayBrowser/#/R-MMU-70241 PCK1 phosphorylates OA to yield PEP IEA Mus musculus 58189 R-MMU-71775 https://reactome.org/PathwayBrowser/#/R-MMU-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Mus musculus 58189 R-MMU-72619 https://reactome.org/PathwayBrowser/#/R-MMU-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Mus musculus 58189 R-MMU-72670 https://reactome.org/PathwayBrowser/#/R-MMU-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Mus musculus 58189 R-MMU-72671 https://reactome.org/PathwayBrowser/#/R-MMU-72671 eIF5B:GTP is hydrolyzed and released IEA Mus musculus 58189 R-MMU-72722 https://reactome.org/PathwayBrowser/#/R-MMU-72722 eIF2 activation IEA Mus musculus 58189 R-MMU-73788 https://reactome.org/PathwayBrowser/#/R-MMU-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Mus musculus 58189 R-MMU-749453 https://reactome.org/PathwayBrowser/#/R-MMU-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Mus musculus 58189 R-MMU-751029 https://reactome.org/PathwayBrowser/#/R-MMU-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Mus musculus 58189 R-MMU-8847534 https://reactome.org/PathwayBrowser/#/R-MMU-8847534 RAB43 hydrolyses GTP IEA Mus musculus 58189 R-MMU-8847883 https://reactome.org/PathwayBrowser/#/R-MMU-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Mus musculus 58189 R-MMU-8848618 https://reactome.org/PathwayBrowser/#/R-MMU-8848618 Activation of RAC1 by the PXN:CRK complex IEA Mus musculus 58189 R-MMU-8849082 https://reactome.org/PathwayBrowser/#/R-MMU-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Mus musculus 58189 R-MMU-8849350 https://reactome.org/PathwayBrowser/#/R-MMU-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Mus musculus 58189 R-MMU-8849353 https://reactome.org/PathwayBrowser/#/R-MMU-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Mus musculus 58189 R-MMU-8850040 https://reactome.org/PathwayBrowser/#/R-MMU-8850040 RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER IEA Mus musculus 58189 R-MMU-8850041 https://reactome.org/PathwayBrowser/#/R-MMU-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Mus musculus 58189 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 58189 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 58189 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 58189 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 58189 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 58189 R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 58189 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 58189 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 58189 R-MMU-8851827 https://reactome.org/PathwayBrowser/#/R-MMU-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Mus musculus 58189 R-MMU-8851877 https://reactome.org/PathwayBrowser/#/R-MMU-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Mus musculus 58189 R-MMU-8851899 https://reactome.org/PathwayBrowser/#/R-MMU-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Mus musculus 58189 R-MMU-8852280 https://reactome.org/PathwayBrowser/#/R-MMU-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Mus musculus 58189 R-MMU-8852298 https://reactome.org/PathwayBrowser/#/R-MMU-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Mus musculus 58189 R-MMU-8852306 https://reactome.org/PathwayBrowser/#/R-MMU-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Mus musculus 58189 R-MMU-8854173 https://reactome.org/PathwayBrowser/#/R-MMU-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Mus musculus 58189 R-MMU-8854255 https://reactome.org/PathwayBrowser/#/R-MMU-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Mus musculus 58189 R-MMU-8854612 https://reactome.org/PathwayBrowser/#/R-MMU-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Mus musculus 58189 R-MMU-8865774 https://reactome.org/PathwayBrowser/#/R-MMU-8865774 TTLLs polyglutamylate tubulin IEA Mus musculus 58189 R-MMU-8867370 https://reactome.org/PathwayBrowser/#/R-MMU-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Mus musculus 58189 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 58189 R-MMU-8868659 https://reactome.org/PathwayBrowser/#/R-MMU-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Mus musculus 58189 R-MMU-8868660 https://reactome.org/PathwayBrowser/#/R-MMU-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Mus musculus 58189 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 58189 R-MMU-8870466 https://reactome.org/PathwayBrowser/#/R-MMU-8870466 RGGT:CHM binds RABs IEA Mus musculus 58189 R-MMU-8870469 https://reactome.org/PathwayBrowser/#/R-MMU-8870469 RGGT geranylgeranylates RAB proteins IEA Mus musculus 58189 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 58189 R-MMU-8871194 https://reactome.org/PathwayBrowser/#/R-MMU-8871194 RAB5 and GAPVD1 bind AP-2 IEA Mus musculus 58189 R-MMU-8875318 https://reactome.org/PathwayBrowser/#/R-MMU-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Mus musculus 58189 R-MMU-8875320 https://reactome.org/PathwayBrowser/#/R-MMU-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Mus musculus 58189 R-MMU-8875568 https://reactome.org/PathwayBrowser/#/R-MMU-8875568 RAPGEF1 activates RAP1 IEA Mus musculus 58189 R-MMU-8875591 https://reactome.org/PathwayBrowser/#/R-MMU-8875591 DOCK7 activates RAC1 IEA Mus musculus 58189 R-MMU-8876188 https://reactome.org/PathwayBrowser/#/R-MMU-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Mus musculus 58189 R-MMU-8876190 https://reactome.org/PathwayBrowser/#/R-MMU-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Mus musculus 58189 R-MMU-8876191 https://reactome.org/PathwayBrowser/#/R-MMU-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Mus musculus 58189 R-MMU-8876193 https://reactome.org/PathwayBrowser/#/R-MMU-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Mus musculus 58189 R-MMU-8876454 https://reactome.org/PathwayBrowser/#/R-MMU-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Mus musculus 58189 R-MMU-8876615 https://reactome.org/PathwayBrowser/#/R-MMU-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Mus musculus 58189 R-MMU-8876616 https://reactome.org/PathwayBrowser/#/R-MMU-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Mus musculus 58189 R-MMU-8876837 https://reactome.org/PathwayBrowser/#/R-MMU-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Mus musculus 58189 R-MMU-8877308 https://reactome.org/PathwayBrowser/#/R-MMU-8877308 MADD exchanges GTP for GDP on RAB27 IEA Mus musculus 58189 R-MMU-8877311 https://reactome.org/PathwayBrowser/#/R-MMU-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Mus musculus 58189 R-MMU-8877451 https://reactome.org/PathwayBrowser/#/R-MMU-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Mus musculus 58189 R-MMU-8877475 https://reactome.org/PathwayBrowser/#/R-MMU-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Mus musculus 58189 R-MMU-8877612 https://reactome.org/PathwayBrowser/#/R-MMU-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Mus musculus 58189 R-MMU-8877760 https://reactome.org/PathwayBrowser/#/R-MMU-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Mus musculus 58189 R-MMU-8877813 https://reactome.org/PathwayBrowser/#/R-MMU-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Mus musculus 58189 R-MMU-8877998 https://reactome.org/PathwayBrowser/#/R-MMU-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Mus musculus 58189 R-MMU-8938815 https://reactome.org/PathwayBrowser/#/R-MMU-8938815 RNF152 polyubiquitinates RRAGA IEA Mus musculus 58189 R-MMU-8938829 https://reactome.org/PathwayBrowser/#/R-MMU-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 IEA Mus musculus 58189 R-MMU-8941613 https://reactome.org/PathwayBrowser/#/R-MMU-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-8941618 https://reactome.org/PathwayBrowser/#/R-MMU-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-8941623 https://reactome.org/PathwayBrowser/#/R-MMU-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-8941628 https://reactome.org/PathwayBrowser/#/R-MMU-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Mus musculus 58189 R-MMU-8944454 https://reactome.org/PathwayBrowser/#/R-MMU-8944454 mTORC1 phosphorylates MAF1 IEA Mus musculus 58189 R-MMU-8944457 https://reactome.org/PathwayBrowser/#/R-MMU-8944457 MAF1 translocates to the nucleus IEA Mus musculus 58189 R-MMU-8951498 https://reactome.org/PathwayBrowser/#/R-MMU-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Mus musculus 58189 R-MMU-8951586 https://reactome.org/PathwayBrowser/#/R-MMU-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Mus musculus 58189 R-MMU-8952716 https://reactome.org/PathwayBrowser/#/R-MMU-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Mus musculus 58189 R-MMU-8952726 https://reactome.org/PathwayBrowser/#/R-MMU-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Mus musculus 58189 R-MMU-8980691 https://reactome.org/PathwayBrowser/#/R-MMU-8980691 RHOA GEFs activate RHOA IEA Mus musculus 58189 R-MMU-8981353 https://reactome.org/PathwayBrowser/#/R-MMU-8981353 RASA1 stimulates RAS GTPase activity IEA Mus musculus 58189 R-MMU-8981637 https://reactome.org/PathwayBrowser/#/R-MMU-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Mus musculus 58189 R-MMU-8982012 https://reactome.org/PathwayBrowser/#/R-MMU-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Mus musculus 58189 R-MMU-8982018 https://reactome.org/PathwayBrowser/#/R-MMU-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Mus musculus 58189 R-MMU-8982020 https://reactome.org/PathwayBrowser/#/R-MMU-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Mus musculus 58189 R-MMU-8982021 https://reactome.org/PathwayBrowser/#/R-MMU-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Mus musculus 58189 R-MMU-8982025 https://reactome.org/PathwayBrowser/#/R-MMU-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Mus musculus 58189 R-MMU-8982026 https://reactome.org/PathwayBrowser/#/R-MMU-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Mus musculus 58189 R-MMU-8985594 https://reactome.org/PathwayBrowser/#/R-MMU-8985594 MYO9B inactivates RHOA IEA Mus musculus 58189 R-MMU-9012761 https://reactome.org/PathwayBrowser/#/R-MMU-9012761 The p75NTR:NgR:MDGI binds RHOA-GDI IEA Mus musculus 58189 R-MMU-9012835 https://reactome.org/PathwayBrowser/#/R-MMU-9012835 GDIs block activation of RHOA IEA Mus musculus 58189 R-MMU-9013021 https://reactome.org/PathwayBrowser/#/R-MMU-9013021 GDIs block activation of RHOB IEA Mus musculus 58189 R-MMU-9013022 https://reactome.org/PathwayBrowser/#/R-MMU-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Mus musculus 58189 R-MMU-9013023 https://reactome.org/PathwayBrowser/#/R-MMU-9013023 RHOB GEFs activate RHOB IEA Mus musculus 58189 R-MMU-9013108 https://reactome.org/PathwayBrowser/#/R-MMU-9013108 GDIs block activation of RHOC IEA Mus musculus 58189 R-MMU-9013109 https://reactome.org/PathwayBrowser/#/R-MMU-9013109 RHOC GEFs activate RHOC IEA Mus musculus 58189 R-MMU-9013111 https://reactome.org/PathwayBrowser/#/R-MMU-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Mus musculus 58189 R-MMU-9013143 https://reactome.org/PathwayBrowser/#/R-MMU-9013143 RAC1 GEFs activate RAC1 IEA Mus musculus 58189 R-MMU-9013144 https://reactome.org/PathwayBrowser/#/R-MMU-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Mus musculus 58189 R-MMU-9013147 https://reactome.org/PathwayBrowser/#/R-MMU-9013147 RAC1 GDIs block activation of RAC1 IEA Mus musculus 58189 R-MMU-9013158 https://reactome.org/PathwayBrowser/#/R-MMU-9013158 CDC42 GDIs block activation of CDC42 IEA Mus musculus 58189 R-MMU-9013159 https://reactome.org/PathwayBrowser/#/R-MMU-9013159 CDC42 GEFs activate CDC42 IEA Mus musculus 58189 R-MMU-9013161 https://reactome.org/PathwayBrowser/#/R-MMU-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Mus musculus 58189 R-MMU-9013435 https://reactome.org/PathwayBrowser/#/R-MMU-9013435 RHOD auto-activates IEA Mus musculus 58189 R-MMU-9013437 https://reactome.org/PathwayBrowser/#/R-MMU-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Mus musculus 58189 R-MMU-9014293 https://reactome.org/PathwayBrowser/#/R-MMU-9014293 RAC2 GDIs block activation of RAC2 IEA Mus musculus 58189 R-MMU-9014295 https://reactome.org/PathwayBrowser/#/R-MMU-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Mus musculus 58189 R-MMU-9014296 https://reactome.org/PathwayBrowser/#/R-MMU-9014296 RAC2 GEFs activate RAC2 IEA Mus musculus 58189 R-MMU-9014433 https://reactome.org/PathwayBrowser/#/R-MMU-9014433 RHOG GEFs activate RHOG IEA Mus musculus 58189 R-MMU-9014434 https://reactome.org/PathwayBrowser/#/R-MMU-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Mus musculus 58189 R-MMU-9014456 https://reactome.org/PathwayBrowser/#/R-MMU-9014456 GDIs block activation of RHOG IEA Mus musculus 58189 R-MMU-9017488 https://reactome.org/PathwayBrowser/#/R-MMU-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Mus musculus 58189 R-MMU-9017491 https://reactome.org/PathwayBrowser/#/R-MMU-9017491 RHOJ GEFs activate RHOJ IEA Mus musculus 58189 R-MMU-9018745 https://reactome.org/PathwayBrowser/#/R-MMU-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Mus musculus 58189 R-MMU-9018747 https://reactome.org/PathwayBrowser/#/R-MMU-9018747 RHOQ GEFs activate RHOQ IEA Mus musculus 58189 R-MMU-9018768 https://reactome.org/PathwayBrowser/#/R-MMU-9018768 RHOU auto-activates IEA Mus musculus 58189 R-MMU-9018798 https://reactome.org/PathwayBrowser/#/R-MMU-9018798 RHOV binds GTP IEA Mus musculus 58189 R-MMU-9018804 https://reactome.org/PathwayBrowser/#/R-MMU-9018804 RAC3 GEFs activate RAC3 IEA Mus musculus 58189 R-MMU-9018806 https://reactome.org/PathwayBrowser/#/R-MMU-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Mus musculus 58189 R-MMU-9018807 https://reactome.org/PathwayBrowser/#/R-MMU-9018807 RAC3 GDIs block activation of RAC3 IEA Mus musculus 58189 R-MMU-9018814 https://reactome.org/PathwayBrowser/#/R-MMU-9018814 RHOT1 hydrolyzes GTP IEA Mus musculus 58189 R-MMU-9018826 https://reactome.org/PathwayBrowser/#/R-MMU-9018826 RHOT2 hydrolyzes GTP IEA Mus musculus 58189 R-MMU-9029152 https://reactome.org/PathwayBrowser/#/R-MMU-9029152 Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Y-Crkl:p-Y-Shc1:Grb2-1:Sos1,p-Y-Vav1 mediates exchange of GDP for GTP bound to Ras TAS Mus musculus 58189 R-MMU-9032798 https://reactome.org/PathwayBrowser/#/R-MMU-9032798 DOCK3 activates RAC1 IEA Mus musculus 58189 R-MMU-9033949 https://reactome.org/PathwayBrowser/#/R-MMU-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Mus musculus 58189 R-MMU-9036301 https://reactome.org/PathwayBrowser/#/R-MMU-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Mus musculus 58189 R-MMU-9036307 https://reactome.org/PathwayBrowser/#/R-MMU-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Mus musculus 58189 R-MMU-9036987 https://reactome.org/PathwayBrowser/#/R-MMU-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Mus musculus 58189 R-MMU-927789 https://reactome.org/PathwayBrowser/#/R-MMU-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Mus musculus 58189 R-MMU-927813 https://reactome.org/PathwayBrowser/#/R-MMU-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Mus musculus 58189 R-MMU-927832 https://reactome.org/PathwayBrowser/#/R-MMU-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Mus musculus 58189 R-MMU-927836 https://reactome.org/PathwayBrowser/#/R-MMU-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Mus musculus 58189 R-MMU-927889 https://reactome.org/PathwayBrowser/#/R-MMU-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Mus musculus 58189 R-MMU-939265 https://reactome.org/PathwayBrowser/#/R-MMU-939265 Activation of Rap1 by membrane-associated GEFs IEA Mus musculus 58189 R-MMU-9603982 https://reactome.org/PathwayBrowser/#/R-MMU-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Mus musculus 58189 R-MMU-9603983 https://reactome.org/PathwayBrowser/#/R-MMU-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Mus musculus 58189 R-MMU-9603984 https://reactome.org/PathwayBrowser/#/R-MMU-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Mus musculus 58189 R-MMU-9605682 https://reactome.org/PathwayBrowser/#/R-MMU-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Mus musculus 58189 R-MMU-9607304 https://reactome.org/PathwayBrowser/#/R-MMU-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Mus musculus 58189 R-MMU-9610428 https://reactome.org/PathwayBrowser/#/R-MMU-9610428 GluN1:GluN2B (Grin1:Grin2b) di-heterotetramers bind Lin7:Cask:Apba1 and Kif17 TAS Mus musculus 58189 R-MMU-9610641 https://reactome.org/PathwayBrowser/#/R-MMU-9610641 Kif17 transports GluN1:GluN2B (Grin1:Grin2b) NMDA receptors to the plasma membrane TAS Mus musculus 58189 R-MMU-9624845 https://reactome.org/PathwayBrowser/#/R-MMU-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Mus musculus 58189 R-MMU-9624893 https://reactome.org/PathwayBrowser/#/R-MMU-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Mus musculus 58189 R-MMU-9632906 https://reactome.org/PathwayBrowser/#/R-MMU-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Mus musculus 58189 R-MMU-9632918 https://reactome.org/PathwayBrowser/#/R-MMU-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Mus musculus 58189 R-MMU-9639286 https://reactome.org/PathwayBrowser/#/R-MMU-9639286 RRAGC,D exchanges GTP for GDP IEA Mus musculus 58189 R-MMU-9640167 https://reactome.org/PathwayBrowser/#/R-MMU-9640167 RRAGA,B exchanges GDP for GTP IEA Mus musculus 58189 R-MMU-9640168 https://reactome.org/PathwayBrowser/#/R-MMU-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Mus musculus 58189 R-MMU-9640175 https://reactome.org/PathwayBrowser/#/R-MMU-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Mus musculus 58189 R-MMU-9640195 https://reactome.org/PathwayBrowser/#/R-MMU-9640195 RRAGA,B hydrolyzes GTP IEA Mus musculus 58189 R-MMU-9645598 https://reactome.org/PathwayBrowser/#/R-MMU-9645598 RRAGC,D hydrolyzes GTP IEA Mus musculus 58189 R-MMU-9645608 https://reactome.org/PathwayBrowser/#/R-MMU-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Mus musculus 58189 R-MMU-9646393 https://reactome.org/PathwayBrowser/#/R-MMU-9646393 Hdac6 binds microtubule TAS Mus musculus 58189 R-MMU-9646468 https://reactome.org/PathwayBrowser/#/R-MMU-9646468 mTORC1 binds RHEB:GTP IEA Mus musculus 58189 R-MMU-9646679 https://reactome.org/PathwayBrowser/#/R-MMU-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Mus musculus 58189 R-MMU-9646685 https://reactome.org/PathwayBrowser/#/R-MMU-9646685 Aggresome dissociates from dynein and microtubule IEA Mus musculus 58189 R-MMU-9648017 https://reactome.org/PathwayBrowser/#/R-MMU-9648017 EML4 binds to microtubules IEA Mus musculus 58189 R-MMU-9648114 https://reactome.org/PathwayBrowser/#/R-MMU-9648114 EML4 recruits NUDC to mitotic spindle IEA Mus musculus 58189 R-MMU-9649733 https://reactome.org/PathwayBrowser/#/R-MMU-9649733 mature p21 RAS binds GDP IEA Mus musculus 58189 R-MMU-9649735 https://reactome.org/PathwayBrowser/#/R-MMU-9649735 Intrinsic nucleotide exchange on RAS IEA Mus musculus 58189 R-MMU-9649736 https://reactome.org/PathwayBrowser/#/R-MMU-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Mus musculus 58189 R-MMU-9668419 https://reactome.org/PathwayBrowser/#/R-MMU-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Mus musculus 58189 R-MMU-9682572 https://reactome.org/PathwayBrowser/#/R-MMU-9682572 Csf1r-associated Sos1 mediates exchange of GTP for GDP bound to Ras TAS Mus musculus 58189 R-MMU-9693111 https://reactome.org/PathwayBrowser/#/R-MMU-9693111 RHOF auto-activates IEA Mus musculus 58189 R-MMU-9693282 https://reactome.org/PathwayBrowser/#/R-MMU-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Mus musculus 58189 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 58189 R-MMU-9717206 https://reactome.org/PathwayBrowser/#/R-MMU-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Mus musculus 58189 R-MMU-9724864 https://reactome.org/PathwayBrowser/#/R-MMU-9724864 Gnat3 exchanges GDP for GTP in Gnat3:Gnb1:Gng13 TAS Mus musculus 58189 R-MMU-9726862 https://reactome.org/PathwayBrowser/#/R-MMU-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Mus musculus 58189 R-MMU-9728664 https://reactome.org/PathwayBrowser/#/R-MMU-9728664 GLP1R binds GLP1R agonists IEA Mus musculus 58189 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 58189 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 58189 R-MMU-9751201 https://reactome.org/PathwayBrowser/#/R-MMU-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Mus musculus 58189 R-MMU-983259 https://reactome.org/PathwayBrowser/#/R-MMU-983259 Kinesins move along microtubules consuming ATP IEA Mus musculus 58189 R-MMU-983266 https://reactome.org/PathwayBrowser/#/R-MMU-983266 Kinesins bind microtubules IEA Mus musculus 58189 R-MMU-983422 https://reactome.org/PathwayBrowser/#/R-MMU-983422 Disassembly of COPII coated vesicle IEA Mus musculus 58189 R-MMU-9836404 https://reactome.org/PathwayBrowser/#/R-MMU-9836404 p-PKR dimer phosphorylates MAPT IEA Mus musculus 58189 R-MMU-9846332 https://reactome.org/PathwayBrowser/#/R-MMU-9846332 FUT1,2 transfer fucose to gangliosides IEA Mus musculus 58189 R-MTU-936583 https://reactome.org/PathwayBrowser/#/R-MTU-936583 APS is phosphorylated to PAPS TAS Mycobacterium tuberculosis 58189 R-NUL-1250468 https://reactome.org/PathwayBrowser/#/R-NUL-1250468 Ras guanyl-nucleotide exchange mediated by Sos1 in complex with GRB2 and P-Erbb2mut TAS Homo sapiens 58189 R-NUL-1250472 https://reactome.org/PathwayBrowser/#/R-NUL-1250472 Ras guanyl-nucleotide exchange mediated by Sos1 bound to GRB2 in complex with P-Shc1:P-Erbb2mut TAS Homo sapiens 58189 R-NUL-428519 https://reactome.org/PathwayBrowser/#/R-NUL-428519 Inactivation of Cdc42 TAS Rattus norvegicus 58189 R-NUL-4551534 https://reactome.org/PathwayBrowser/#/R-NUL-4551534 RFzd binds trimeric G-proteins TAS Mus musculus 58189 R-NUL-8867463 https://reactome.org/PathwayBrowser/#/R-NUL-8867463 Ccps deglutamylate tubulin TAS Homo sapiens 58189 R-NUL-8955728 https://reactome.org/PathwayBrowser/#/R-NUL-8955728 TTCP hydrolyzes the terminal L-Tyr residue from alpha-tubulin TAS Bos taurus 58189 R-NUL-8955873 https://reactome.org/PathwayBrowser/#/R-NUL-8955873 Polyglutamylase complex (Ttll1) polyglutamylates alpha subunits of tubulin TAS Homo sapiens 58189 R-NUL-9032387 https://reactome.org/PathwayBrowser/#/R-NUL-9032387 Ntrk2 activates Ras signaling through Frs2 TAS Homo sapiens 58189 R-NUL-9033341 https://reactome.org/PathwayBrowser/#/R-NUL-9033341 Ntrk2 and Cdk5 promote activation of Rac1 by Tiam1 TAS Homo sapiens 58189 R-NUL-9616949 https://reactome.org/PathwayBrowser/#/R-NUL-9616949 Ntrk3 activates Ras TAS Rattus norvegicus 58189 R-NUL-9617449 https://reactome.org/PathwayBrowser/#/R-NUL-9617449 Rasgrf1 promotes activation of HRAS TAS Rattus norvegicus 58189 R-NUL-9619539 https://reactome.org/PathwayBrowser/#/R-NUL-9619539 AMPK-negatively regulates binding of MAPT to microtubules TAS Bos taurus 58189 R-NUL-9646387 https://reactome.org/PathwayBrowser/#/R-NUL-9646387 Dynein motors transport misfolded proteins TAS Cercopithecus aethiops 58189 R-NUL-9726861 https://reactome.org/PathwayBrowser/#/R-NUL-9726861 Src phosphorylates RHOU TAS Homo sapiens 58189 R-NUL-9729192 https://reactome.org/PathwayBrowser/#/R-NUL-9729192 Gnat3 exchanges GDP for GTP in Gnat3:GNB5:GNG3 TAS Bos taurus 58189 R-OCU-159603 https://reactome.org/PathwayBrowser/#/R-OCU-159603 Hydrolysis of reEF1A:GTP TAS Oryctolagus cuniculus 58189 R-PFA-1008248 https://reactome.org/PathwayBrowser/#/R-PFA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Plasmodium falciparum 58189 R-PFA-110133 https://reactome.org/PathwayBrowser/#/R-PFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Plasmodium falciparum 58189 R-PFA-111524 https://reactome.org/PathwayBrowser/#/R-PFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Plasmodium falciparum 58189 R-PFA-203977 https://reactome.org/PathwayBrowser/#/R-PFA-203977 SAR1 Activation And Membrane Binding IEA Plasmodium falciparum 58189 R-PFA-350769 https://reactome.org/PathwayBrowser/#/R-PFA-350769 trans-Golgi Network Coat Activation IEA Plasmodium falciparum 58189 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 58189 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 58189 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 58189 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 58189 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 58189 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 58189 R-PFA-5618328 https://reactome.org/PathwayBrowser/#/R-PFA-5618328 ATAT acetylates microtubules IEA Plasmodium falciparum 58189 R-PFA-5618331 https://reactome.org/PathwayBrowser/#/R-PFA-5618331 HDAC6 deacetylates microtubules IEA Plasmodium falciparum 58189 R-PFA-5623508 https://reactome.org/PathwayBrowser/#/R-PFA-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Plasmodium falciparum 58189 R-PFA-5694409 https://reactome.org/PathwayBrowser/#/R-PFA-5694409 Nucleotide exchange on RAB1 IEA Plasmodium falciparum 58189 R-PFA-5694439 https://reactome.org/PathwayBrowser/#/R-PFA-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Plasmodium falciparum 58189 R-PFA-5694527 https://reactome.org/PathwayBrowser/#/R-PFA-5694527 Loss of SAR1B GTPase IEA Plasmodium falciparum 58189 R-PFA-6807868 https://reactome.org/PathwayBrowser/#/R-PFA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Plasmodium falciparum 58189 R-PFA-6811411 https://reactome.org/PathwayBrowser/#/R-PFA-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Plasmodium falciparum 58189 R-PFA-6811414 https://reactome.org/PathwayBrowser/#/R-PFA-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Plasmodium falciparum 58189 R-PFA-6811418 https://reactome.org/PathwayBrowser/#/R-PFA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Plasmodium falciparum 58189 R-PFA-6814833 https://reactome.org/PathwayBrowser/#/R-PFA-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Plasmodium falciparum 58189 R-PFA-71775 https://reactome.org/PathwayBrowser/#/R-PFA-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Plasmodium falciparum 58189 R-PFA-72670 https://reactome.org/PathwayBrowser/#/R-PFA-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Plasmodium falciparum 58189 R-PFA-72671 https://reactome.org/PathwayBrowser/#/R-PFA-72671 eIF5B:GTP is hydrolyzed and released IEA Plasmodium falciparum 58189 R-PFA-72722 https://reactome.org/PathwayBrowser/#/R-PFA-72722 eIF2 activation IEA Plasmodium falciparum 58189 R-PFA-73788 https://reactome.org/PathwayBrowser/#/R-PFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Plasmodium falciparum 58189 R-PFA-8847534 https://reactome.org/PathwayBrowser/#/R-PFA-8847534 RAB43 hydrolyses GTP IEA Plasmodium falciparum 58189 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 58189 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58189 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58189 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 58189 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58189 R-PFA-8854255 https://reactome.org/PathwayBrowser/#/R-PFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 58189 R-PFA-8865774 https://reactome.org/PathwayBrowser/#/R-PFA-8865774 TTLLs polyglutamylate tubulin IEA Plasmodium falciparum 58189 R-PFA-8870466 https://reactome.org/PathwayBrowser/#/R-PFA-8870466 RGGT:CHM binds RABs IEA Plasmodium falciparum 58189 R-PFA-8870469 https://reactome.org/PathwayBrowser/#/R-PFA-8870469 RGGT geranylgeranylates RAB proteins IEA Plasmodium falciparum 58189 R-PFA-8875320 https://reactome.org/PathwayBrowser/#/R-PFA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Plasmodium falciparum 58189 R-PFA-8877451 https://reactome.org/PathwayBrowser/#/R-PFA-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Plasmodium falciparum 58189 R-PFA-8877475 https://reactome.org/PathwayBrowser/#/R-PFA-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Plasmodium falciparum 58189 R-PFA-927789 https://reactome.org/PathwayBrowser/#/R-PFA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Plasmodium falciparum 58189 R-PFA-927889 https://reactome.org/PathwayBrowser/#/R-PFA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Plasmodium falciparum 58189 R-PFA-9624845 https://reactome.org/PathwayBrowser/#/R-PFA-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Plasmodium falciparum 58189 R-PFA-9646685 https://reactome.org/PathwayBrowser/#/R-PFA-9646685 Aggresome dissociates from dynein and microtubule IEA Plasmodium falciparum 58189 R-RNO-1008248 https://reactome.org/PathwayBrowser/#/R-RNO-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Rattus norvegicus 58189 R-RNO-1028788 https://reactome.org/PathwayBrowser/#/R-RNO-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Rattus norvegicus 58189 R-RNO-110133 https://reactome.org/PathwayBrowser/#/R-RNO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Rattus norvegicus 58189 R-RNO-111524 https://reactome.org/PathwayBrowser/#/R-RNO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Rattus norvegicus 58189 R-RNO-112037 https://reactome.org/PathwayBrowser/#/R-RNO-112037 Inactivation of PLC beta IEA Rattus norvegicus 58189 R-RNO-112377 https://reactome.org/PathwayBrowser/#/R-RNO-112377 Grb2:Sos2:p-Y-Irs1 mediated nucleotide exchange of p21 Ras (IRS) TAS Rattus norvegicus 58189 R-RNO-112378 https://reactome.org/PathwayBrowser/#/R-RNO-112378 SOS mediated nucleotide exchange of RAS (SHC) TAS Rattus norvegicus 58189 R-RNO-114544 https://reactome.org/PathwayBrowser/#/R-RNO-114544 p115-RhoGEF activation of RHOA IEA Rattus norvegicus 58189 R-RNO-114552 https://reactome.org/PathwayBrowser/#/R-RNO-114552 Thrombin-activated PARs activate G12/13 IEA Rattus norvegicus 58189 R-RNO-114558 https://reactome.org/PathwayBrowser/#/R-RNO-114558 Thrombin-activated PARs activate Gq IEA Rattus norvegicus 58189 R-RNO-1168636 https://reactome.org/PathwayBrowser/#/R-RNO-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Rattus norvegicus 58189 R-RNO-1250383 https://reactome.org/PathwayBrowser/#/R-RNO-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Rattus norvegicus 58189 R-RNO-1306972 https://reactome.org/PathwayBrowser/#/R-RNO-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Rattus norvegicus 58189 R-RNO-1433415 https://reactome.org/PathwayBrowser/#/R-RNO-1433415 Activation of RAC1 IEA Rattus norvegicus 58189 R-RNO-1433471 https://reactome.org/PathwayBrowser/#/R-RNO-1433471 Activation of RAS by p-KIT bound SOS1 IEA Rattus norvegicus 58189 R-RNO-156913 https://reactome.org/PathwayBrowser/#/R-RNO-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Rattus norvegicus 58189 R-RNO-162721 https://reactome.org/PathwayBrowser/#/R-RNO-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Rattus norvegicus 58189 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus 58189 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus 58189 R-RNO-165195 https://reactome.org/PathwayBrowser/#/R-RNO-165195 GTP loading by Rheb IEA Rattus norvegicus 58189 R-RNO-165680 https://reactome.org/PathwayBrowser/#/R-RNO-165680 Formation of active mTORC1 complex IEA Rattus norvegicus 58189 R-RNO-165692 https://reactome.org/PathwayBrowser/#/R-RNO-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Rattus norvegicus 58189 R-RNO-165718 https://reactome.org/PathwayBrowser/#/R-RNO-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Rattus norvegicus 58189 R-RNO-167415 https://reactome.org/PathwayBrowser/#/R-RNO-167415 G-protein alpha subunit is inactivated IEA Rattus norvegicus 58189 R-RNO-167419 https://reactome.org/PathwayBrowser/#/R-RNO-167419 The receptor:G-protein complex releases GDP IEA Rattus norvegicus 58189 R-RNO-169904 https://reactome.org/PathwayBrowser/#/R-RNO-169904 C3G stimulates nucleotide exchange on Rap1 IEA Rattus norvegicus 58189 R-RNO-170026 https://reactome.org/PathwayBrowser/#/R-RNO-170026 Protons are translocated from the intermembrane space to the matrix IEA Rattus norvegicus 58189 R-RNO-170666 https://reactome.org/PathwayBrowser/#/R-RNO-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Rattus norvegicus 58189 R-RNO-170674 https://reactome.org/PathwayBrowser/#/R-RNO-170674 Dissociation of the Gi alpha:G olf complex IEA Rattus norvegicus 58189 R-RNO-170677 https://reactome.org/PathwayBrowser/#/R-RNO-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Rattus norvegicus 58189 R-RNO-170685 https://reactome.org/PathwayBrowser/#/R-RNO-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Rattus norvegicus 58189 R-RNO-170686 https://reactome.org/PathwayBrowser/#/R-RNO-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Rattus norvegicus 58189 R-RNO-177938 https://reactome.org/PathwayBrowser/#/R-RNO-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Rattus norvegicus 58189 R-RNO-177945 https://reactome.org/PathwayBrowser/#/R-RNO-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Rattus norvegicus 58189 R-RNO-182041 https://reactome.org/PathwayBrowser/#/R-RNO-182041 Endocytosis of clathrin-coated vesicle TAS Rattus norvegicus 58189 R-RNO-182053 https://reactome.org/PathwayBrowser/#/R-RNO-182053 C3G stimulates nucleotide exchange on Rap1 TAS Rattus norvegicus 58189 R-RNO-186834 https://reactome.org/PathwayBrowser/#/R-RNO-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Rattus norvegicus 58189 R-RNO-187670 https://reactome.org/PathwayBrowser/#/R-RNO-187670 Activation of Src by Ral TAS Rattus norvegicus 58189 R-RNO-187759 https://reactome.org/PathwayBrowser/#/R-RNO-187759 Rit is activated TAS Rattus norvegicus 58189 R-RNO-187762 https://reactome.org/PathwayBrowser/#/R-RNO-187762 Guanine nucleotide exchange on Ral TAS Rattus norvegicus 58189 R-RNO-190520 https://reactome.org/PathwayBrowser/#/R-RNO-190520 Association of Golgi transport vesicles with microtubules IEA Rattus norvegicus 58189 R-RNO-193646 https://reactome.org/PathwayBrowser/#/R-RNO-193646 NGF binding to p75NTR inactivates RHOA IEA Rattus norvegicus 58189 R-RNO-193668 https://reactome.org/PathwayBrowser/#/R-RNO-193668 p75NTR and RHOA-GDI interact IEA Rattus norvegicus 58189 R-RNO-193696 https://reactome.org/PathwayBrowser/#/R-RNO-193696 The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA IEA Rattus norvegicus 58189 R-RNO-194518 https://reactome.org/PathwayBrowser/#/R-RNO-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Rattus norvegicus 58189 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus 58189 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus 58189 R-RNO-203977 https://reactome.org/PathwayBrowser/#/R-RNO-203977 SAR1 Activation And Membrane Binding IEA Rattus norvegicus 58189 R-RNO-205039 https://reactome.org/PathwayBrowser/#/R-RNO-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Rattus norvegicus 58189 R-RNO-210977 https://reactome.org/PathwayBrowser/#/R-RNO-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Rattus norvegicus 58189 R-RNO-2130641 https://reactome.org/PathwayBrowser/#/R-RNO-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Rattus norvegicus 58189 R-RNO-2130725 https://reactome.org/PathwayBrowser/#/R-RNO-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Rattus norvegicus 58189 R-RNO-2179407 https://reactome.org/PathwayBrowser/#/R-RNO-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Rattus norvegicus 58189 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus 58189 R-RNO-2424476 https://reactome.org/PathwayBrowser/#/R-RNO-2424476 Activation of RAC1 by VAV2/3 IEA Rattus norvegicus 58189 R-RNO-2424477 https://reactome.org/PathwayBrowser/#/R-RNO-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Rattus norvegicus 58189 R-RNO-2457808 https://reactome.org/PathwayBrowser/#/R-RNO-2457808 Rab8A/13/14 Exchange GDP for GTP TAS Rattus norvegicus 58189 R-RNO-2467809 https://reactome.org/PathwayBrowser/#/R-RNO-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Rattus norvegicus 58189 R-RNO-2467811 https://reactome.org/PathwayBrowser/#/R-RNO-2467811 Separation of sister chromatids IEA Rattus norvegicus 58189 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus 58189 R-RNO-2484822 https://reactome.org/PathwayBrowser/#/R-RNO-2484822 Kinetochore assembly IEA Rattus norvegicus 58189 R-RNO-2584246 https://reactome.org/PathwayBrowser/#/R-RNO-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Rattus norvegicus 58189 R-RNO-2730840 https://reactome.org/PathwayBrowser/#/R-RNO-2730840 Activation of RAC1 by VAV IEA Rattus norvegicus 58189 R-RNO-350769 https://reactome.org/PathwayBrowser/#/R-RNO-350769 trans-Golgi Network Coat Activation IEA Rattus norvegicus 58189 R-RNO-354173 https://reactome.org/PathwayBrowser/#/R-RNO-354173 Activation of Rap1 by cytosolic GEFs IEA Rattus norvegicus 58189 R-RNO-372819 https://reactome.org/PathwayBrowser/#/R-RNO-372819 PCK2 phosphorylates OA to yield PEP IEA Rattus norvegicus 58189 R-RNO-375302 https://reactome.org/PathwayBrowser/#/R-RNO-375302 Kinetochore capture of astral microtubules IEA Rattus norvegicus 58189 R-RNO-377186 https://reactome.org/PathwayBrowser/#/R-RNO-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Rattus norvegicus 58189 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 58189 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 58189 R-RNO-380316 https://reactome.org/PathwayBrowser/#/R-RNO-380316 Association of NuMA with microtubules IEA Rattus norvegicus 58189 R-RNO-380979 https://reactome.org/PathwayBrowser/#/R-RNO-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Rattus norvegicus 58189 R-RNO-381612 https://reactome.org/PathwayBrowser/#/R-RNO-381612 GLP1R binds GLP1 IEA Rattus norvegicus 58189 R-RNO-381727 https://reactome.org/PathwayBrowser/#/R-RNO-381727 RAP1A exchanges GDP for GTP IEA Rattus norvegicus 58189 R-RNO-389348 https://reactome.org/PathwayBrowser/#/R-RNO-389348 Activation of Rac1 by pVav1 IEA Rattus norvegicus 58189 R-RNO-389350 https://reactome.org/PathwayBrowser/#/R-RNO-389350 Activation of Cdc42 by pVav1 IEA Rattus norvegicus 58189 R-RNO-392054 https://reactome.org/PathwayBrowser/#/R-RNO-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Rattus norvegicus 58189 R-RNO-392195 https://reactome.org/PathwayBrowser/#/R-RNO-392195 Gi activation by P2Y purinoceptor 12 IEA Rattus norvegicus 58189 R-RNO-392513 https://reactome.org/PathwayBrowser/#/R-RNO-392513 Rap1 signal termination by Rap1GAPs IEA Rattus norvegicus 58189 R-RNO-3928592 https://reactome.org/PathwayBrowser/#/R-RNO-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Rattus norvegicus 58189 R-RNO-3928628 https://reactome.org/PathwayBrowser/#/R-RNO-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 58189 R-RNO-3928642 https://reactome.org/PathwayBrowser/#/R-RNO-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 58189 R-RNO-3928651 https://reactome.org/PathwayBrowser/#/R-RNO-3928651 NGEF exchanges GTP for GDP on RHOA IEA Rattus norvegicus 58189 R-RNO-3965444 https://reactome.org/PathwayBrowser/#/R-RNO-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-400092 https://reactome.org/PathwayBrowser/#/R-RNO-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Rattus norvegicus 58189 R-RNO-4093336 https://reactome.org/PathwayBrowser/#/R-RNO-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 58189 R-RNO-4093339 https://reactome.org/PathwayBrowser/#/R-RNO-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Rattus norvegicus 58189 R-RNO-416530 https://reactome.org/PathwayBrowser/#/R-RNO-416530 FFAR1:FFAR1 ligands activate Gq IEA Rattus norvegicus 58189 R-RNO-416559 https://reactome.org/PathwayBrowser/#/R-RNO-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Rattus norvegicus 58189 R-RNO-416588 https://reactome.org/PathwayBrowser/#/R-RNO-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Rattus norvegicus 58189 R-RNO-418850 https://reactome.org/PathwayBrowser/#/R-RNO-418850 Activation of Cdc42 IEA Rattus norvegicus 58189 R-RNO-418856 https://reactome.org/PathwayBrowser/#/R-RNO-418856 Activation of Rac1 IEA Rattus norvegicus 58189 R-RNO-419166 https://reactome.org/PathwayBrowser/#/R-RNO-419166 GEFs activate RhoA,B,C IEA Rattus norvegicus 58189 R-RNO-420883 https://reactome.org/PathwayBrowser/#/R-RNO-420883 Opsins act as GEFs for G alpha-t IEA Rattus norvegicus 58189 R-RNO-421831 https://reactome.org/PathwayBrowser/#/R-RNO-421831 trans-Golgi Network Coat Assembly IEA Rattus norvegicus 58189 R-RNO-421835 https://reactome.org/PathwayBrowser/#/R-RNO-421835 trans-Golgi Network Vesicle Scission IEA Rattus norvegicus 58189 R-RNO-428750 https://reactome.org/PathwayBrowser/#/R-RNO-428750 Gq activation by TP receptor IEA Rattus norvegicus 58189 R-RNO-428917 https://reactome.org/PathwayBrowser/#/R-RNO-428917 G13 activation by TP receptor IEA Rattus norvegicus 58189 R-RNO-432195 https://reactome.org/PathwayBrowser/#/R-RNO-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Rattus norvegicus 58189 R-RNO-432706 https://reactome.org/PathwayBrowser/#/R-RNO-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Rattus norvegicus 58189 R-RNO-432707 https://reactome.org/PathwayBrowser/#/R-RNO-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Rattus norvegicus 58189 R-RNO-442273 https://reactome.org/PathwayBrowser/#/R-RNO-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Rattus norvegicus 58189 R-RNO-442291 https://reactome.org/PathwayBrowser/#/R-RNO-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Rattus norvegicus 58189 R-RNO-442314 https://reactome.org/PathwayBrowser/#/R-RNO-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Rattus norvegicus 58189 R-RNO-445064 https://reactome.org/PathwayBrowser/#/R-RNO-445064 Activation of Rac1 by VAV2 IEA Rattus norvegicus 58189 R-RNO-445071 https://reactome.org/PathwayBrowser/#/R-RNO-445071 Reinsertion of L1 into the plasma membrane IEA Rattus norvegicus 58189 R-RNO-446208 https://reactome.org/PathwayBrowser/#/R-RNO-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Rattus norvegicus 58189 R-RNO-446218 https://reactome.org/PathwayBrowser/#/R-RNO-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Rattus norvegicus 58189 R-RNO-446954 https://reactome.org/PathwayBrowser/#/R-RNO-446954 Activation of G(s) by the Glucagon-like peptide-1 receptor (Glp1r, rat) TAS Rattus norvegicus 58189 R-RNO-447074 https://reactome.org/PathwayBrowser/#/R-RNO-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Rattus norvegicus 58189 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 58189 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 58189 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 58189 R-RNO-5218839 https://reactome.org/PathwayBrowser/#/R-RNO-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Rattus norvegicus 58189 R-RNO-5218850 https://reactome.org/PathwayBrowser/#/R-RNO-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 58189 R-RNO-5333610 https://reactome.org/PathwayBrowser/#/R-RNO-5333610 Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec-tRNA(Sec):Eefsec:GTP is hydrolysed to Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec and Eefsec:GDP by Eefsec TAS Rattus norvegicus 58189 R-RNO-5419271 https://reactome.org/PathwayBrowser/#/R-RNO-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Rattus norvegicus 58189 R-RNO-5419273 https://reactome.org/PathwayBrowser/#/R-RNO-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Rattus norvegicus 58189 R-RNO-555065 https://reactome.org/PathwayBrowser/#/R-RNO-555065 Formation of clathrin coated vesicle IEA Rattus norvegicus 58189 R-RNO-5610733 https://reactome.org/PathwayBrowser/#/R-RNO-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Rattus norvegicus 58189 R-RNO-5610767 https://reactome.org/PathwayBrowser/#/R-RNO-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Rattus norvegicus 58189 R-RNO-5617816 https://reactome.org/PathwayBrowser/#/R-RNO-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus 58189 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 58189 R-RNO-5618328 https://reactome.org/PathwayBrowser/#/R-RNO-5618328 ATAT acetylates microtubules IEA Rattus norvegicus 58189 R-RNO-5623508 https://reactome.org/PathwayBrowser/#/R-RNO-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Rattus norvegicus 58189 R-RNO-5623513 https://reactome.org/PathwayBrowser/#/R-RNO-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Rattus norvegicus 58189 R-RNO-5623519 https://reactome.org/PathwayBrowser/#/R-RNO-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Rattus norvegicus 58189 R-RNO-5623521 https://reactome.org/PathwayBrowser/#/R-RNO-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus 58189 R-RNO-5624949 https://reactome.org/PathwayBrowser/#/R-RNO-5624949 Assembly of the anterograde IFT train IEA Rattus norvegicus 58189 R-RNO-5624952 https://reactome.org/PathwayBrowser/#/R-RNO-5624952 Assembly of the retrograde IFT train IEA Rattus norvegicus 58189 R-RNO-5625416 https://reactome.org/PathwayBrowser/#/R-RNO-5625416 Anterograde IFT IEA Rattus norvegicus 58189 R-RNO-5625421 https://reactome.org/PathwayBrowser/#/R-RNO-5625421 The anterograde IFT train dissociates IEA Rattus norvegicus 58189 R-RNO-5625424 https://reactome.org/PathwayBrowser/#/R-RNO-5625424 The retrograde IFT train dissociates IEA Rattus norvegicus 58189 R-RNO-5625426 https://reactome.org/PathwayBrowser/#/R-RNO-5625426 Retrograde IFT IEA Rattus norvegicus 58189 R-RNO-5653957 https://reactome.org/PathwayBrowser/#/R-RNO-5653957 Rag dimer formation IEA Rattus norvegicus 58189 R-RNO-5653968 https://reactome.org/PathwayBrowser/#/R-RNO-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Rattus norvegicus 58189 R-RNO-5653974 https://reactome.org/PathwayBrowser/#/R-RNO-5653974 Ragulator binds Rag dimers IEA Rattus norvegicus 58189 R-RNO-5654392 https://reactome.org/PathwayBrowser/#/R-RNO-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-5654402 https://reactome.org/PathwayBrowser/#/R-RNO-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-5654413 https://reactome.org/PathwayBrowser/#/R-RNO-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-5654426 https://reactome.org/PathwayBrowser/#/R-RNO-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-5654600 https://reactome.org/PathwayBrowser/#/R-RNO-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-5654618 https://reactome.org/PathwayBrowser/#/R-RNO-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-5654647 https://reactome.org/PathwayBrowser/#/R-RNO-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-5654663 https://reactome.org/PathwayBrowser/#/R-RNO-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-5658231 https://reactome.org/PathwayBrowser/#/R-RNO-5658231 RAS GAPs stimulate RAS GTPase activity IEA Rattus norvegicus 58189 R-RNO-5665809 https://reactome.org/PathwayBrowser/#/R-RNO-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Rattus norvegicus 58189 R-RNO-5666169 https://reactome.org/PathwayBrowser/#/R-RNO-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Rattus norvegicus 58189 R-RNO-5672010 https://reactome.org/PathwayBrowser/#/R-RNO-5672010 Active MTORC1 phosphorylates ULK1 IEA Rattus norvegicus 58189 R-RNO-5672017 https://reactome.org/PathwayBrowser/#/R-RNO-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Rattus norvegicus 58189 R-RNO-5672329 https://reactome.org/PathwayBrowser/#/R-RNO-5672329 IQGAP1 binds CLIP1 and microtubules IEA Rattus norvegicus 58189 R-RNO-5672817 https://reactome.org/PathwayBrowser/#/R-RNO-5672817 Active MTORC1 binds the ULK1 complex IEA Rattus norvegicus 58189 R-RNO-5672824 https://reactome.org/PathwayBrowser/#/R-RNO-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Rattus norvegicus 58189 R-RNO-5672828 https://reactome.org/PathwayBrowser/#/R-RNO-5672828 mTORC1 phosphorylates AKT1S1 IEA Rattus norvegicus 58189 R-RNO-5672843 https://reactome.org/PathwayBrowser/#/R-RNO-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Rattus norvegicus 58189 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-5673768 https://reactome.org/PathwayBrowser/#/R-RNO-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Rattus norvegicus 58189 R-RNO-5675790 https://reactome.org/PathwayBrowser/#/R-RNO-5675790 MTORC1 dissociates from ULK complex IEA Rattus norvegicus 58189 R-RNO-5694409 https://reactome.org/PathwayBrowser/#/R-RNO-5694409 Nucleotide exchange on RAB1 IEA Rattus norvegicus 58189 R-RNO-5694439 https://reactome.org/PathwayBrowser/#/R-RNO-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Rattus norvegicus 58189 R-RNO-5694527 https://reactome.org/PathwayBrowser/#/R-RNO-5694527 Loss of SAR1B GTPase IEA Rattus norvegicus 58189 R-RNO-6788611 https://reactome.org/PathwayBrowser/#/R-RNO-6788611 HYKK phosphorylates 5HLYS IEA Rattus norvegicus 58189 R-RNO-6807866 https://reactome.org/PathwayBrowser/#/R-RNO-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Rattus norvegicus 58189 R-RNO-6807868 https://reactome.org/PathwayBrowser/#/R-RNO-6807868 GBF1 stimulates ARF nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-6807877 https://reactome.org/PathwayBrowser/#/R-RNO-6807877 ARFGAPs stimulate ARF GTPase activity IEA Rattus norvegicus 58189 R-RNO-6809003 https://reactome.org/PathwayBrowser/#/R-RNO-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Rattus norvegicus 58189 R-RNO-6809006 https://reactome.org/PathwayBrowser/#/R-RNO-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Rattus norvegicus 58189 R-RNO-6809010 https://reactome.org/PathwayBrowser/#/R-RNO-6809010 COPI vesicle uncoating IEA Rattus norvegicus 58189 R-RNO-6811411 https://reactome.org/PathwayBrowser/#/R-RNO-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Rattus norvegicus 58189 R-RNO-6811414 https://reactome.org/PathwayBrowser/#/R-RNO-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Rattus norvegicus 58189 R-RNO-6811418 https://reactome.org/PathwayBrowser/#/R-RNO-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Rattus norvegicus 58189 R-RNO-6811423 https://reactome.org/PathwayBrowser/#/R-RNO-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Rattus norvegicus 58189 R-RNO-6811426 https://reactome.org/PathwayBrowser/#/R-RNO-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Rattus norvegicus 58189 R-RNO-6811427 https://reactome.org/PathwayBrowser/#/R-RNO-6811427 COPI vesicle uncoating at the ER IEA Rattus norvegicus 58189 R-RNO-6811428 https://reactome.org/PathwayBrowser/#/R-RNO-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Rattus norvegicus 58189 R-RNO-6811429 https://reactome.org/PathwayBrowser/#/R-RNO-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-6814671 https://reactome.org/PathwayBrowser/#/R-RNO-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Rattus norvegicus 58189 R-RNO-6814682 https://reactome.org/PathwayBrowser/#/R-RNO-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Rattus norvegicus 58189 R-RNO-6814833 https://reactome.org/PathwayBrowser/#/R-RNO-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Rattus norvegicus 58189 R-RNO-70241 https://reactome.org/PathwayBrowser/#/R-RNO-70241 PCK1 phosphorylates OA to yield PEP IEA Rattus norvegicus 58189 R-RNO-71775 https://reactome.org/PathwayBrowser/#/R-RNO-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Rattus norvegicus 58189 R-RNO-72670 https://reactome.org/PathwayBrowser/#/R-RNO-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Rattus norvegicus 58189 R-RNO-72671 https://reactome.org/PathwayBrowser/#/R-RNO-72671 eIF5B:GTP is hydrolyzed and released IEA Rattus norvegicus 58189 R-RNO-72722 https://reactome.org/PathwayBrowser/#/R-RNO-72722 eIF2 activation IEA Rattus norvegicus 58189 R-RNO-73788 https://reactome.org/PathwayBrowser/#/R-RNO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Rattus norvegicus 58189 R-RNO-749453 https://reactome.org/PathwayBrowser/#/R-RNO-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Rattus norvegicus 58189 R-RNO-751029 https://reactome.org/PathwayBrowser/#/R-RNO-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Rattus norvegicus 58189 R-RNO-8847534 https://reactome.org/PathwayBrowser/#/R-RNO-8847534 RAB43 hydrolyses GTP IEA Rattus norvegicus 58189 R-RNO-8847883 https://reactome.org/PathwayBrowser/#/R-RNO-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Rattus norvegicus 58189 R-RNO-8848618 https://reactome.org/PathwayBrowser/#/R-RNO-8848618 Activation of RAC1 by the PXN:CRK complex IEA Rattus norvegicus 58189 R-RNO-8849082 https://reactome.org/PathwayBrowser/#/R-RNO-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Rattus norvegicus 58189 R-RNO-8849350 https://reactome.org/PathwayBrowser/#/R-RNO-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Rattus norvegicus 58189 R-RNO-8849353 https://reactome.org/PathwayBrowser/#/R-RNO-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Rattus norvegicus 58189 R-RNO-8850040 https://reactome.org/PathwayBrowser/#/R-RNO-8850040 RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER IEA Rattus norvegicus 58189 R-RNO-8850041 https://reactome.org/PathwayBrowser/#/R-RNO-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Rattus norvegicus 58189 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58189 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58189 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58189 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58189 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58189 R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58189 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58189 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58189 R-RNO-8851827 https://reactome.org/PathwayBrowser/#/R-RNO-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Rattus norvegicus 58189 R-RNO-8851877 https://reactome.org/PathwayBrowser/#/R-RNO-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Rattus norvegicus 58189 R-RNO-8851899 https://reactome.org/PathwayBrowser/#/R-RNO-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Rattus norvegicus 58189 R-RNO-8852280 https://reactome.org/PathwayBrowser/#/R-RNO-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Rattus norvegicus 58189 R-RNO-8852298 https://reactome.org/PathwayBrowser/#/R-RNO-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Rattus norvegicus 58189 R-RNO-8852306 https://reactome.org/PathwayBrowser/#/R-RNO-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Rattus norvegicus 58189 R-RNO-8854173 https://reactome.org/PathwayBrowser/#/R-RNO-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Rattus norvegicus 58189 R-RNO-8854255 https://reactome.org/PathwayBrowser/#/R-RNO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 58189 R-RNO-8854612 https://reactome.org/PathwayBrowser/#/R-RNO-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Rattus norvegicus 58189 R-RNO-8865774 https://reactome.org/PathwayBrowser/#/R-RNO-8865774 TTLLs polyglutamylate tubulin IEA Rattus norvegicus 58189 R-RNO-8867370 https://reactome.org/PathwayBrowser/#/R-RNO-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Rattus norvegicus 58189 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 58189 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus 58189 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus 58189 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 58189 R-RNO-8870466 https://reactome.org/PathwayBrowser/#/R-RNO-8870466 RGGT:CHM binds RABs IEA Rattus norvegicus 58189 R-RNO-8870469 https://reactome.org/PathwayBrowser/#/R-RNO-8870469 RGGT geranylgeranylates RAB proteins IEA Rattus norvegicus 58189 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 58189 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus 58189 R-RNO-8875318 https://reactome.org/PathwayBrowser/#/R-RNO-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Rattus norvegicus 58189 R-RNO-8875320 https://reactome.org/PathwayBrowser/#/R-RNO-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Rattus norvegicus 58189 R-RNO-8875568 https://reactome.org/PathwayBrowser/#/R-RNO-8875568 RAPGEF1 activates RAP1 IEA Rattus norvegicus 58189 R-RNO-8875591 https://reactome.org/PathwayBrowser/#/R-RNO-8875591 DOCK7 activates RAC1 IEA Rattus norvegicus 58189 R-RNO-8876188 https://reactome.org/PathwayBrowser/#/R-RNO-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Rattus norvegicus 58189 R-RNO-8876190 https://reactome.org/PathwayBrowser/#/R-RNO-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Rattus norvegicus 58189 R-RNO-8876191 https://reactome.org/PathwayBrowser/#/R-RNO-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Rattus norvegicus 58189 R-RNO-8876193 https://reactome.org/PathwayBrowser/#/R-RNO-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Rattus norvegicus 58189 R-RNO-8876454 https://reactome.org/PathwayBrowser/#/R-RNO-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Rattus norvegicus 58189 R-RNO-8876615 https://reactome.org/PathwayBrowser/#/R-RNO-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Rattus norvegicus 58189 R-RNO-8876616 https://reactome.org/PathwayBrowser/#/R-RNO-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Rattus norvegicus 58189 R-RNO-8876837 https://reactome.org/PathwayBrowser/#/R-RNO-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Rattus norvegicus 58189 R-RNO-8877308 https://reactome.org/PathwayBrowser/#/R-RNO-8877308 MADD exchanges GTP for GDP on RAB27 IEA Rattus norvegicus 58189 R-RNO-8877311 https://reactome.org/PathwayBrowser/#/R-RNO-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Rattus norvegicus 58189 R-RNO-8877451 https://reactome.org/PathwayBrowser/#/R-RNO-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Rattus norvegicus 58189 R-RNO-8877475 https://reactome.org/PathwayBrowser/#/R-RNO-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Rattus norvegicus 58189 R-RNO-8877612 https://reactome.org/PathwayBrowser/#/R-RNO-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Rattus norvegicus 58189 R-RNO-8877760 https://reactome.org/PathwayBrowser/#/R-RNO-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Rattus norvegicus 58189 R-RNO-8877813 https://reactome.org/PathwayBrowser/#/R-RNO-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Rattus norvegicus 58189 R-RNO-8877998 https://reactome.org/PathwayBrowser/#/R-RNO-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Rattus norvegicus 58189 R-RNO-8941613 https://reactome.org/PathwayBrowser/#/R-RNO-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-8941618 https://reactome.org/PathwayBrowser/#/R-RNO-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-8941623 https://reactome.org/PathwayBrowser/#/R-RNO-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-8941628 https://reactome.org/PathwayBrowser/#/R-RNO-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus 58189 R-RNO-8944454 https://reactome.org/PathwayBrowser/#/R-RNO-8944454 mTORC1 phosphorylates MAF1 IEA Rattus norvegicus 58189 R-RNO-8944457 https://reactome.org/PathwayBrowser/#/R-RNO-8944457 MAF1 translocates to the nucleus IEA Rattus norvegicus 58189 R-RNO-8951498 https://reactome.org/PathwayBrowser/#/R-RNO-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Rattus norvegicus 58189 R-RNO-8951586 https://reactome.org/PathwayBrowser/#/R-RNO-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Rattus norvegicus 58189 R-RNO-8952716 https://reactome.org/PathwayBrowser/#/R-RNO-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Rattus norvegicus 58189 R-RNO-8952726 https://reactome.org/PathwayBrowser/#/R-RNO-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Rattus norvegicus 58189 R-RNO-8980691 https://reactome.org/PathwayBrowser/#/R-RNO-8980691 RHOA GEFs activate RHOA IEA Rattus norvegicus 58189 R-RNO-8981353 https://reactome.org/PathwayBrowser/#/R-RNO-8981353 RASA1 stimulates RAS GTPase activity IEA Rattus norvegicus 58189 R-RNO-8981637 https://reactome.org/PathwayBrowser/#/R-RNO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Rattus norvegicus 58189 R-RNO-8982012 https://reactome.org/PathwayBrowser/#/R-RNO-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Rattus norvegicus 58189 R-RNO-8982018 https://reactome.org/PathwayBrowser/#/R-RNO-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Rattus norvegicus 58189 R-RNO-8982020 https://reactome.org/PathwayBrowser/#/R-RNO-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Rattus norvegicus 58189 R-RNO-8982021 https://reactome.org/PathwayBrowser/#/R-RNO-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Rattus norvegicus 58189 R-RNO-8982025 https://reactome.org/PathwayBrowser/#/R-RNO-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Rattus norvegicus 58189 R-RNO-8982026 https://reactome.org/PathwayBrowser/#/R-RNO-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Rattus norvegicus 58189 R-RNO-8985594 https://reactome.org/PathwayBrowser/#/R-RNO-8985594 MYO9B inactivates RHOA IEA Rattus norvegicus 58189 R-RNO-9012761 https://reactome.org/PathwayBrowser/#/R-RNO-9012761 The p75NTR:NgR:MDGI binds RHOA-GDI IEA Rattus norvegicus 58189 R-RNO-9012835 https://reactome.org/PathwayBrowser/#/R-RNO-9012835 GDIs block activation of RHOA IEA Rattus norvegicus 58189 R-RNO-9013021 https://reactome.org/PathwayBrowser/#/R-RNO-9013021 GDIs block activation of RHOB IEA Rattus norvegicus 58189 R-RNO-9013022 https://reactome.org/PathwayBrowser/#/R-RNO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Rattus norvegicus 58189 R-RNO-9013023 https://reactome.org/PathwayBrowser/#/R-RNO-9013023 RHOB GEFs activate RHOB IEA Rattus norvegicus 58189 R-RNO-9013143 https://reactome.org/PathwayBrowser/#/R-RNO-9013143 RAC1 GEFs activate RAC1 IEA Rattus norvegicus 58189 R-RNO-9013144 https://reactome.org/PathwayBrowser/#/R-RNO-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Rattus norvegicus 58189 R-RNO-9013147 https://reactome.org/PathwayBrowser/#/R-RNO-9013147 RAC1 GDIs block activation of RAC1 IEA Rattus norvegicus 58189 R-RNO-9013158 https://reactome.org/PathwayBrowser/#/R-RNO-9013158 CDC42 GDIs block activation of CDC42 IEA Rattus norvegicus 58189 R-RNO-9013159 https://reactome.org/PathwayBrowser/#/R-RNO-9013159 CDC42 GEFs activate CDC42 IEA Rattus norvegicus 58189 R-RNO-9013161 https://reactome.org/PathwayBrowser/#/R-RNO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Rattus norvegicus 58189 R-RNO-9013435 https://reactome.org/PathwayBrowser/#/R-RNO-9013435 RHOD auto-activates IEA Rattus norvegicus 58189 R-RNO-9013437 https://reactome.org/PathwayBrowser/#/R-RNO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Rattus norvegicus 58189 R-RNO-9014293 https://reactome.org/PathwayBrowser/#/R-RNO-9014293 RAC2 GDIs block activation of RAC2 IEA Rattus norvegicus 58189 R-RNO-9014295 https://reactome.org/PathwayBrowser/#/R-RNO-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Rattus norvegicus 58189 R-RNO-9014296 https://reactome.org/PathwayBrowser/#/R-RNO-9014296 RAC2 GEFs activate RAC2 IEA Rattus norvegicus 58189 R-RNO-9014433 https://reactome.org/PathwayBrowser/#/R-RNO-9014433 RHOG GEFs activate RHOG IEA Rattus norvegicus 58189 R-RNO-9014434 https://reactome.org/PathwayBrowser/#/R-RNO-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Rattus norvegicus 58189 R-RNO-9014456 https://reactome.org/PathwayBrowser/#/R-RNO-9014456 GDIs block activation of RHOG IEA Rattus norvegicus 58189 R-RNO-9017488 https://reactome.org/PathwayBrowser/#/R-RNO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Rattus norvegicus 58189 R-RNO-9017491 https://reactome.org/PathwayBrowser/#/R-RNO-9017491 RHOJ GEFs activate RHOJ IEA Rattus norvegicus 58189 R-RNO-9018745 https://reactome.org/PathwayBrowser/#/R-RNO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Rattus norvegicus 58189 R-RNO-9018747 https://reactome.org/PathwayBrowser/#/R-RNO-9018747 RHOQ GEFs activate RHOQ IEA Rattus norvegicus 58189 R-RNO-9018768 https://reactome.org/PathwayBrowser/#/R-RNO-9018768 RHOU auto-activates IEA Rattus norvegicus 58189 R-RNO-9018798 https://reactome.org/PathwayBrowser/#/R-RNO-9018798 RHOV binds GTP IEA Rattus norvegicus 58189 R-RNO-9018826 https://reactome.org/PathwayBrowser/#/R-RNO-9018826 RHOT2 hydrolyzes GTP IEA Rattus norvegicus 58189 R-RNO-9030763 https://reactome.org/PathwayBrowser/#/R-RNO-9030763 Ntrk2 activates Ras signaling through Shc1 TAS Rattus norvegicus 58189 R-RNO-9032798 https://reactome.org/PathwayBrowser/#/R-RNO-9032798 DOCK3 activates RAC1 IEA Rattus norvegicus 58189 R-RNO-9033949 https://reactome.org/PathwayBrowser/#/R-RNO-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Rattus norvegicus 58189 R-RNO-9036987 https://reactome.org/PathwayBrowser/#/R-RNO-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Rattus norvegicus 58189 R-RNO-927789 https://reactome.org/PathwayBrowser/#/R-RNO-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Rattus norvegicus 58189 R-RNO-927813 https://reactome.org/PathwayBrowser/#/R-RNO-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Rattus norvegicus 58189 R-RNO-927832 https://reactome.org/PathwayBrowser/#/R-RNO-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Rattus norvegicus 58189 R-RNO-927836 https://reactome.org/PathwayBrowser/#/R-RNO-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Rattus norvegicus 58189 R-RNO-927889 https://reactome.org/PathwayBrowser/#/R-RNO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Rattus norvegicus 58189 R-RNO-939265 https://reactome.org/PathwayBrowser/#/R-RNO-939265 Activation of Rap1 by membrane-associated GEFs IEA Rattus norvegicus 58189 R-RNO-9603982 https://reactome.org/PathwayBrowser/#/R-RNO-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Rattus norvegicus 58189 R-RNO-9603983 https://reactome.org/PathwayBrowser/#/R-RNO-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Rattus norvegicus 58189 R-RNO-9603984 https://reactome.org/PathwayBrowser/#/R-RNO-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Rattus norvegicus 58189 R-RNO-9605682 https://reactome.org/PathwayBrowser/#/R-RNO-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Rattus norvegicus 58189 R-RNO-9607304 https://reactome.org/PathwayBrowser/#/R-RNO-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Rattus norvegicus 58189 R-RNO-9619811 https://reactome.org/PathwayBrowser/#/R-RNO-9619811 p-S516-Arhgef7 activates Rac1 TAS Rattus norvegicus 58189 R-RNO-9624845 https://reactome.org/PathwayBrowser/#/R-RNO-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Rattus norvegicus 58189 R-RNO-9624893 https://reactome.org/PathwayBrowser/#/R-RNO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Rattus norvegicus 58189 R-RNO-9632906 https://reactome.org/PathwayBrowser/#/R-RNO-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Rattus norvegicus 58189 R-RNO-9632918 https://reactome.org/PathwayBrowser/#/R-RNO-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Rattus norvegicus 58189 R-RNO-9639286 https://reactome.org/PathwayBrowser/#/R-RNO-9639286 RRAGC,D exchanges GTP for GDP IEA Rattus norvegicus 58189 R-RNO-9640167 https://reactome.org/PathwayBrowser/#/R-RNO-9640167 RRAGA,B exchanges GDP for GTP IEA Rattus norvegicus 58189 R-RNO-9640168 https://reactome.org/PathwayBrowser/#/R-RNO-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Rattus norvegicus 58189 R-RNO-9640175 https://reactome.org/PathwayBrowser/#/R-RNO-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Rattus norvegicus 58189 R-RNO-9640195 https://reactome.org/PathwayBrowser/#/R-RNO-9640195 RRAGA,B hydrolyzes GTP IEA Rattus norvegicus 58189 R-RNO-9645598 https://reactome.org/PathwayBrowser/#/R-RNO-9645598 RRAGC,D hydrolyzes GTP IEA Rattus norvegicus 58189 R-RNO-9645608 https://reactome.org/PathwayBrowser/#/R-RNO-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Rattus norvegicus 58189 R-RNO-9646468 https://reactome.org/PathwayBrowser/#/R-RNO-9646468 mTORC1 binds RHEB:GTP IEA Rattus norvegicus 58189 R-RNO-9646679 https://reactome.org/PathwayBrowser/#/R-RNO-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Rattus norvegicus 58189 R-RNO-9646685 https://reactome.org/PathwayBrowser/#/R-RNO-9646685 Aggresome dissociates from dynein and microtubule IEA Rattus norvegicus 58189 R-RNO-9648017 https://reactome.org/PathwayBrowser/#/R-RNO-9648017 EML4 binds to microtubules IEA Rattus norvegicus 58189 R-RNO-9648114 https://reactome.org/PathwayBrowser/#/R-RNO-9648114 EML4 recruits NUDC to mitotic spindle IEA Rattus norvegicus 58189 R-RNO-9649733 https://reactome.org/PathwayBrowser/#/R-RNO-9649733 mature p21 RAS binds GDP IEA Rattus norvegicus 58189 R-RNO-9649735 https://reactome.org/PathwayBrowser/#/R-RNO-9649735 Intrinsic nucleotide exchange on RAS IEA Rattus norvegicus 58189 R-RNO-9649736 https://reactome.org/PathwayBrowser/#/R-RNO-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Rattus norvegicus 58189 R-RNO-9668419 https://reactome.org/PathwayBrowser/#/R-RNO-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Rattus norvegicus 58189 R-RNO-9693111 https://reactome.org/PathwayBrowser/#/R-RNO-9693111 RHOF auto-activates IEA Rattus norvegicus 58189 R-RNO-9693282 https://reactome.org/PathwayBrowser/#/R-RNO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Rattus norvegicus 58189 R-RNO-9713234 https://reactome.org/PathwayBrowser/#/R-RNO-9713234 Gnal exchanges GDP for GTP TAS Rattus norvegicus 58189 R-RNO-9717206 https://reactome.org/PathwayBrowser/#/R-RNO-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Rattus norvegicus 58189 R-RNO-9726862 https://reactome.org/PathwayBrowser/#/R-RNO-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Rattus norvegicus 58189 R-RNO-9728664 https://reactome.org/PathwayBrowser/#/R-RNO-9728664 GLP1R binds GLP1R agonists IEA Rattus norvegicus 58189 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 58189 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 58189 R-RNO-9751201 https://reactome.org/PathwayBrowser/#/R-RNO-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Rattus norvegicus 58189 R-RNO-983259 https://reactome.org/PathwayBrowser/#/R-RNO-983259 Kinesins move along microtubules consuming ATP IEA Rattus norvegicus 58189 R-RNO-983266 https://reactome.org/PathwayBrowser/#/R-RNO-983266 Kinesins bind microtubules IEA Rattus norvegicus 58189 R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus 58189 R-RNO-9836404 https://reactome.org/PathwayBrowser/#/R-RNO-9836404 p-PKR dimer phosphorylates MAPT IEA Rattus norvegicus 58189 R-RNO-9846332 https://reactome.org/PathwayBrowser/#/R-RNO-9846332 FUT1,2 transfer fucose to gangliosides IEA Rattus norvegicus 58189 R-SCE-1008248 https://reactome.org/PathwayBrowser/#/R-SCE-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Saccharomyces cerevisiae 58189 R-SCE-110133 https://reactome.org/PathwayBrowser/#/R-SCE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Saccharomyces cerevisiae 58189 R-SCE-111524 https://reactome.org/PathwayBrowser/#/R-SCE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Saccharomyces cerevisiae 58189 R-SCE-112037 https://reactome.org/PathwayBrowser/#/R-SCE-112037 Inactivation of PLC beta IEA Saccharomyces cerevisiae 58189 R-SCE-141687 https://reactome.org/PathwayBrowser/#/R-SCE-141687 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex TAS Saccharomyces cerevisiae 58189 R-SCE-141698 https://reactome.org/PathwayBrowser/#/R-SCE-141698 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex TAS Saccharomyces cerevisiae 58189 R-SCE-156913 https://reactome.org/PathwayBrowser/#/R-SCE-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Saccharomyces cerevisiae 58189 R-SCE-165195 https://reactome.org/PathwayBrowser/#/R-SCE-165195 GTP loading by Rheb IEA Saccharomyces cerevisiae 58189 R-SCE-167415 https://reactome.org/PathwayBrowser/#/R-SCE-167415 G-protein alpha subunit is inactivated IEA Saccharomyces cerevisiae 58189 R-SCE-203977 https://reactome.org/PathwayBrowser/#/R-SCE-203977 SAR1 Activation And Membrane Binding IEA Saccharomyces cerevisiae 58189 R-SCE-350769 https://reactome.org/PathwayBrowser/#/R-SCE-350769 trans-Golgi Network Coat Activation IEA Saccharomyces cerevisiae 58189 R-SCE-354173 https://reactome.org/PathwayBrowser/#/R-SCE-354173 Activation of Rap1 by cytosolic GEFs IEA Saccharomyces cerevisiae 58189 R-SCE-381727 https://reactome.org/PathwayBrowser/#/R-SCE-381727 RAP1A exchanges GDP for GTP IEA Saccharomyces cerevisiae 58189 R-SCE-419166 https://reactome.org/PathwayBrowser/#/R-SCE-419166 GEFs activate RhoA,B,C IEA Saccharomyces cerevisiae 58189 R-SCE-446208 https://reactome.org/PathwayBrowser/#/R-SCE-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Saccharomyces cerevisiae 58189 R-SCE-446218 https://reactome.org/PathwayBrowser/#/R-SCE-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Saccharomyces cerevisiae 58189 R-SCE-449324 https://reactome.org/PathwayBrowser/#/R-SCE-449324 Addition of the fourth and fifth mannose to the N-glycan precursor skeleton by Alg11 TAS Saccharomyces cerevisiae 58189 R-SCE-449748 https://reactome.org/PathwayBrowser/#/R-SCE-449748 Addition of a third mannose to the N-glycan precursor by Alg2 TAS Saccharomyces cerevisiae 58189 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 58189 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 58189 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 58189 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 58189 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 58189 R-SCE-5623508 https://reactome.org/PathwayBrowser/#/R-SCE-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Saccharomyces cerevisiae 58189 R-SCE-5653957 https://reactome.org/PathwayBrowser/#/R-SCE-5653957 Rag dimer formation IEA Saccharomyces cerevisiae 58189 R-SCE-5694409 https://reactome.org/PathwayBrowser/#/R-SCE-5694409 Nucleotide exchange on RAB1 IEA Saccharomyces cerevisiae 58189 R-SCE-5694439 https://reactome.org/PathwayBrowser/#/R-SCE-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Saccharomyces cerevisiae 58189 R-SCE-5694527 https://reactome.org/PathwayBrowser/#/R-SCE-5694527 Loss of SAR1B GTPase IEA Saccharomyces cerevisiae 58189 R-SCE-6807866 https://reactome.org/PathwayBrowser/#/R-SCE-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Saccharomyces cerevisiae 58189 R-SCE-6807868 https://reactome.org/PathwayBrowser/#/R-SCE-6807868 GBF1 stimulates ARF nucleotide exchange IEA Saccharomyces cerevisiae 58189 R-SCE-6807877 https://reactome.org/PathwayBrowser/#/R-SCE-6807877 ARFGAPs stimulate ARF GTPase activity IEA Saccharomyces cerevisiae 58189 R-SCE-6811411 https://reactome.org/PathwayBrowser/#/R-SCE-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Saccharomyces cerevisiae 58189 R-SCE-6811414 https://reactome.org/PathwayBrowser/#/R-SCE-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Saccharomyces cerevisiae 58189 R-SCE-6811418 https://reactome.org/PathwayBrowser/#/R-SCE-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Saccharomyces cerevisiae 58189 R-SCE-6811427 https://reactome.org/PathwayBrowser/#/R-SCE-6811427 COPI vesicle uncoating at the ER IEA Saccharomyces cerevisiae 58189 R-SCE-6811428 https://reactome.org/PathwayBrowser/#/R-SCE-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Saccharomyces cerevisiae 58189 R-SCE-6811429 https://reactome.org/PathwayBrowser/#/R-SCE-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Saccharomyces cerevisiae 58189 R-SCE-6814833 https://reactome.org/PathwayBrowser/#/R-SCE-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Saccharomyces cerevisiae 58189 R-SCE-72670 https://reactome.org/PathwayBrowser/#/R-SCE-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Saccharomyces cerevisiae 58189 R-SCE-72671 https://reactome.org/PathwayBrowser/#/R-SCE-72671 eIF5B:GTP is hydrolyzed and released IEA Saccharomyces cerevisiae 58189 R-SCE-72722 https://reactome.org/PathwayBrowser/#/R-SCE-72722 eIF2 activation IEA Saccharomyces cerevisiae 58189 R-SCE-73788 https://reactome.org/PathwayBrowser/#/R-SCE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Saccharomyces cerevisiae 58189 R-SCE-8847883 https://reactome.org/PathwayBrowser/#/R-SCE-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Saccharomyces cerevisiae 58189 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58189 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 58189 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58189 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58189 R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 58189 R-SCE-8854255 https://reactome.org/PathwayBrowser/#/R-SCE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 58189 R-SCE-8870466 https://reactome.org/PathwayBrowser/#/R-SCE-8870466 RGGT:CHM binds RABs IEA Saccharomyces cerevisiae 58189 R-SCE-8870469 https://reactome.org/PathwayBrowser/#/R-SCE-8870469 RGGT geranylgeranylates RAB proteins IEA Saccharomyces cerevisiae 58189 R-SCE-8875318 https://reactome.org/PathwayBrowser/#/R-SCE-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Saccharomyces cerevisiae 58189 R-SCE-8875320 https://reactome.org/PathwayBrowser/#/R-SCE-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Saccharomyces cerevisiae 58189 R-SCE-8876190 https://reactome.org/PathwayBrowser/#/R-SCE-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Saccharomyces cerevisiae 58189 R-SCE-8876193 https://reactome.org/PathwayBrowser/#/R-SCE-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Saccharomyces cerevisiae 58189 R-SCE-8877311 https://reactome.org/PathwayBrowser/#/R-SCE-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Saccharomyces cerevisiae 58189 R-SCE-8877451 https://reactome.org/PathwayBrowser/#/R-SCE-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Saccharomyces cerevisiae 58189 R-SCE-8877475 https://reactome.org/PathwayBrowser/#/R-SCE-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Saccharomyces cerevisiae 58189 R-SCE-8981637 https://reactome.org/PathwayBrowser/#/R-SCE-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Saccharomyces cerevisiae 58189 R-SCE-8982012 https://reactome.org/PathwayBrowser/#/R-SCE-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Saccharomyces cerevisiae 58189 R-SCE-8982018 https://reactome.org/PathwayBrowser/#/R-SCE-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Saccharomyces cerevisiae 58189 R-SCE-8982020 https://reactome.org/PathwayBrowser/#/R-SCE-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Saccharomyces cerevisiae 58189 R-SCE-8982021 https://reactome.org/PathwayBrowser/#/R-SCE-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Saccharomyces cerevisiae 58189 R-SCE-8982025 https://reactome.org/PathwayBrowser/#/R-SCE-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Saccharomyces cerevisiae 58189 R-SCE-8982026 https://reactome.org/PathwayBrowser/#/R-SCE-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Saccharomyces cerevisiae 58189 R-SCE-9012835 https://reactome.org/PathwayBrowser/#/R-SCE-9012835 GDIs block activation of RHOA IEA Saccharomyces cerevisiae 58189 R-SCE-9013021 https://reactome.org/PathwayBrowser/#/R-SCE-9013021 GDIs block activation of RHOB IEA Saccharomyces cerevisiae 58189 R-SCE-9013022 https://reactome.org/PathwayBrowser/#/R-SCE-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Saccharomyces cerevisiae 58189 R-SCE-9013108 https://reactome.org/PathwayBrowser/#/R-SCE-9013108 GDIs block activation of RHOC IEA Saccharomyces cerevisiae 58189 R-SCE-9013111 https://reactome.org/PathwayBrowser/#/R-SCE-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Saccharomyces cerevisiae 58189 R-SCE-9013158 https://reactome.org/PathwayBrowser/#/R-SCE-9013158 CDC42 GDIs block activation of CDC42 IEA Saccharomyces cerevisiae 58189 R-SCE-9013159 https://reactome.org/PathwayBrowser/#/R-SCE-9013159 CDC42 GEFs activate CDC42 IEA Saccharomyces cerevisiae 58189 R-SCE-9013161 https://reactome.org/PathwayBrowser/#/R-SCE-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Saccharomyces cerevisiae 58189 R-SCE-9013435 https://reactome.org/PathwayBrowser/#/R-SCE-9013435 RHOD auto-activates IEA Saccharomyces cerevisiae 58189 R-SCE-9013437 https://reactome.org/PathwayBrowser/#/R-SCE-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Saccharomyces cerevisiae 58189 R-SCE-9017488 https://reactome.org/PathwayBrowser/#/R-SCE-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Saccharomyces cerevisiae 58189 R-SCE-9018745 https://reactome.org/PathwayBrowser/#/R-SCE-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Saccharomyces cerevisiae 58189 R-SCE-9018747 https://reactome.org/PathwayBrowser/#/R-SCE-9018747 RHOQ GEFs activate RHOQ IEA Saccharomyces cerevisiae 58189 R-SCE-9018768 https://reactome.org/PathwayBrowser/#/R-SCE-9018768 RHOU auto-activates IEA Saccharomyces cerevisiae 58189 R-SCE-9018798 https://reactome.org/PathwayBrowser/#/R-SCE-9018798 RHOV binds GTP IEA Saccharomyces cerevisiae 58189 R-SCE-9018814 https://reactome.org/PathwayBrowser/#/R-SCE-9018814 RHOT1 hydrolyzes GTP IEA Saccharomyces cerevisiae 58189 R-SCE-9018826 https://reactome.org/PathwayBrowser/#/R-SCE-9018826 RHOT2 hydrolyzes GTP IEA Saccharomyces cerevisiae 58189 R-SCE-927789 https://reactome.org/PathwayBrowser/#/R-SCE-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Saccharomyces cerevisiae 58189 R-SCE-927836 https://reactome.org/PathwayBrowser/#/R-SCE-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Saccharomyces cerevisiae 58189 R-SCE-927889 https://reactome.org/PathwayBrowser/#/R-SCE-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Saccharomyces cerevisiae 58189 R-SCE-939265 https://reactome.org/PathwayBrowser/#/R-SCE-939265 Activation of Rap1 by membrane-associated GEFs IEA Saccharomyces cerevisiae 58189 R-SCE-9624845 https://reactome.org/PathwayBrowser/#/R-SCE-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Saccharomyces cerevisiae 58189 R-SCE-9624893 https://reactome.org/PathwayBrowser/#/R-SCE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Saccharomyces cerevisiae 58189 R-SCE-9639286 https://reactome.org/PathwayBrowser/#/R-SCE-9639286 RRAGC,D exchanges GTP for GDP IEA Saccharomyces cerevisiae 58189 R-SCE-9640195 https://reactome.org/PathwayBrowser/#/R-SCE-9640195 RRAGA,B hydrolyzes GTP IEA Saccharomyces cerevisiae 58189 R-SCE-9645598 https://reactome.org/PathwayBrowser/#/R-SCE-9645598 RRAGC,D hydrolyzes GTP IEA Saccharomyces cerevisiae 58189 R-SCE-9645608 https://reactome.org/PathwayBrowser/#/R-SCE-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Saccharomyces cerevisiae 58189 R-SCE-9646468 https://reactome.org/PathwayBrowser/#/R-SCE-9646468 mTORC1 binds RHEB:GTP IEA Saccharomyces cerevisiae 58189 R-SCE-9693111 https://reactome.org/PathwayBrowser/#/R-SCE-9693111 RHOF auto-activates IEA Saccharomyces cerevisiae 58189 R-SCE-9693282 https://reactome.org/PathwayBrowser/#/R-SCE-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Saccharomyces cerevisiae 58189 R-SCE-9726862 https://reactome.org/PathwayBrowser/#/R-SCE-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Saccharomyces cerevisiae 58189 R-SPO-110133 https://reactome.org/PathwayBrowser/#/R-SPO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Schizosaccharomyces pombe 58189 R-SPO-111524 https://reactome.org/PathwayBrowser/#/R-SPO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Schizosaccharomyces pombe 58189 R-SPO-112037 https://reactome.org/PathwayBrowser/#/R-SPO-112037 Inactivation of PLC beta IEA Schizosaccharomyces pombe 58189 R-SPO-156913 https://reactome.org/PathwayBrowser/#/R-SPO-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Schizosaccharomyces pombe 58189 R-SPO-165195 https://reactome.org/PathwayBrowser/#/R-SPO-165195 GTP loading by Rheb IEA Schizosaccharomyces pombe 58189 R-SPO-167415 https://reactome.org/PathwayBrowser/#/R-SPO-167415 G-protein alpha subunit is inactivated IEA Schizosaccharomyces pombe 58189 R-SPO-203977 https://reactome.org/PathwayBrowser/#/R-SPO-203977 SAR1 Activation And Membrane Binding IEA Schizosaccharomyces pombe 58189 R-SPO-350769 https://reactome.org/PathwayBrowser/#/R-SPO-350769 trans-Golgi Network Coat Activation IEA Schizosaccharomyces pombe 58189 R-SPO-419166 https://reactome.org/PathwayBrowser/#/R-SPO-419166 GEFs activate RhoA,B,C IEA Schizosaccharomyces pombe 58189 R-SPO-446208 https://reactome.org/PathwayBrowser/#/R-SPO-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Schizosaccharomyces pombe 58189 R-SPO-446218 https://reactome.org/PathwayBrowser/#/R-SPO-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Schizosaccharomyces pombe 58189 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 58189 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 58189 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 58189 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 58189 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 58189 R-SPO-5623508 https://reactome.org/PathwayBrowser/#/R-SPO-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Schizosaccharomyces pombe 58189 R-SPO-5653957 https://reactome.org/PathwayBrowser/#/R-SPO-5653957 Rag dimer formation IEA Schizosaccharomyces pombe 58189 R-SPO-5694409 https://reactome.org/PathwayBrowser/#/R-SPO-5694409 Nucleotide exchange on RAB1 IEA Schizosaccharomyces pombe 58189 R-SPO-5694439 https://reactome.org/PathwayBrowser/#/R-SPO-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Schizosaccharomyces pombe 58189 R-SPO-5694527 https://reactome.org/PathwayBrowser/#/R-SPO-5694527 Loss of SAR1B GTPase IEA Schizosaccharomyces pombe 58189 R-SPO-6807866 https://reactome.org/PathwayBrowser/#/R-SPO-6807866 GBF1 recruits ARF:GDP to the ERGIC IEA Schizosaccharomyces pombe 58189 R-SPO-6807868 https://reactome.org/PathwayBrowser/#/R-SPO-6807868 GBF1 stimulates ARF nucleotide exchange IEA Schizosaccharomyces pombe 58189 R-SPO-6807877 https://reactome.org/PathwayBrowser/#/R-SPO-6807877 ARFGAPs stimulate ARF GTPase activity IEA Schizosaccharomyces pombe 58189 R-SPO-6811411 https://reactome.org/PathwayBrowser/#/R-SPO-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Schizosaccharomyces pombe 58189 R-SPO-6811414 https://reactome.org/PathwayBrowser/#/R-SPO-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Schizosaccharomyces pombe 58189 R-SPO-6811418 https://reactome.org/PathwayBrowser/#/R-SPO-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Schizosaccharomyces pombe 58189 R-SPO-6811427 https://reactome.org/PathwayBrowser/#/R-SPO-6811427 COPI vesicle uncoating at the ER IEA Schizosaccharomyces pombe 58189 R-SPO-6811428 https://reactome.org/PathwayBrowser/#/R-SPO-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Schizosaccharomyces pombe 58189 R-SPO-6811429 https://reactome.org/PathwayBrowser/#/R-SPO-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Schizosaccharomyces pombe 58189 R-SPO-6814833 https://reactome.org/PathwayBrowser/#/R-SPO-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP IEA Schizosaccharomyces pombe 58189 R-SPO-72619 https://reactome.org/PathwayBrowser/#/R-SPO-72619 eIF2:GTP is hydrolyzed, eIFs are released IEA Schizosaccharomyces pombe 58189 R-SPO-72670 https://reactome.org/PathwayBrowser/#/R-SPO-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Schizosaccharomyces pombe 58189 R-SPO-72671 https://reactome.org/PathwayBrowser/#/R-SPO-72671 eIF5B:GTP is hydrolyzed and released IEA Schizosaccharomyces pombe 58189 R-SPO-72722 https://reactome.org/PathwayBrowser/#/R-SPO-72722 eIF2 activation IEA Schizosaccharomyces pombe 58189 R-SPO-73788 https://reactome.org/PathwayBrowser/#/R-SPO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Schizosaccharomyces pombe 58189 R-SPO-8847534 https://reactome.org/PathwayBrowser/#/R-SPO-8847534 RAB43 hydrolyses GTP IEA Schizosaccharomyces pombe 58189 R-SPO-8847883 https://reactome.org/PathwayBrowser/#/R-SPO-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Schizosaccharomyces pombe 58189 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58189 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 58189 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58189 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58189 R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 58189 R-SPO-8854255 https://reactome.org/PathwayBrowser/#/R-SPO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 58189 R-SPO-8868660 https://reactome.org/PathwayBrowser/#/R-SPO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Schizosaccharomyces pombe 58189 R-SPO-8870466 https://reactome.org/PathwayBrowser/#/R-SPO-8870466 RGGT:CHM binds RABs IEA Schizosaccharomyces pombe 58189 R-SPO-8870469 https://reactome.org/PathwayBrowser/#/R-SPO-8870469 RGGT geranylgeranylates RAB proteins IEA Schizosaccharomyces pombe 58189 R-SPO-8875318 https://reactome.org/PathwayBrowser/#/R-SPO-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Schizosaccharomyces pombe 58189 R-SPO-8875320 https://reactome.org/PathwayBrowser/#/R-SPO-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Schizosaccharomyces pombe 58189 R-SPO-8876190 https://reactome.org/PathwayBrowser/#/R-SPO-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Schizosaccharomyces pombe 58189 R-SPO-8876193 https://reactome.org/PathwayBrowser/#/R-SPO-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Schizosaccharomyces pombe 58189 R-SPO-8876454 https://reactome.org/PathwayBrowser/#/R-SPO-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Schizosaccharomyces pombe 58189 R-SPO-8877475 https://reactome.org/PathwayBrowser/#/R-SPO-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Schizosaccharomyces pombe 58189 R-SPO-8981637 https://reactome.org/PathwayBrowser/#/R-SPO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Schizosaccharomyces pombe 58189 R-SPO-8982012 https://reactome.org/PathwayBrowser/#/R-SPO-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Schizosaccharomyces pombe 58189 R-SPO-8982018 https://reactome.org/PathwayBrowser/#/R-SPO-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Schizosaccharomyces pombe 58189 R-SPO-8982020 https://reactome.org/PathwayBrowser/#/R-SPO-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Schizosaccharomyces pombe 58189 R-SPO-8982021 https://reactome.org/PathwayBrowser/#/R-SPO-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Schizosaccharomyces pombe 58189 R-SPO-8982025 https://reactome.org/PathwayBrowser/#/R-SPO-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Schizosaccharomyces pombe 58189 R-SPO-8982026 https://reactome.org/PathwayBrowser/#/R-SPO-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Schizosaccharomyces pombe 58189 R-SPO-9012835 https://reactome.org/PathwayBrowser/#/R-SPO-9012835 GDIs block activation of RHOA IEA Schizosaccharomyces pombe 58189 R-SPO-9013021 https://reactome.org/PathwayBrowser/#/R-SPO-9013021 GDIs block activation of RHOB IEA Schizosaccharomyces pombe 58189 R-SPO-9013022 https://reactome.org/PathwayBrowser/#/R-SPO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Schizosaccharomyces pombe 58189 R-SPO-9013108 https://reactome.org/PathwayBrowser/#/R-SPO-9013108 GDIs block activation of RHOC IEA Schizosaccharomyces pombe 58189 R-SPO-9013111 https://reactome.org/PathwayBrowser/#/R-SPO-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Schizosaccharomyces pombe 58189 R-SPO-9013158 https://reactome.org/PathwayBrowser/#/R-SPO-9013158 CDC42 GDIs block activation of CDC42 IEA Schizosaccharomyces pombe 58189 R-SPO-9013159 https://reactome.org/PathwayBrowser/#/R-SPO-9013159 CDC42 GEFs activate CDC42 IEA Schizosaccharomyces pombe 58189 R-SPO-9013161 https://reactome.org/PathwayBrowser/#/R-SPO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Schizosaccharomyces pombe 58189 R-SPO-9013435 https://reactome.org/PathwayBrowser/#/R-SPO-9013435 RHOD auto-activates IEA Schizosaccharomyces pombe 58189 R-SPO-9013437 https://reactome.org/PathwayBrowser/#/R-SPO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Schizosaccharomyces pombe 58189 R-SPO-9017488 https://reactome.org/PathwayBrowser/#/R-SPO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Schizosaccharomyces pombe 58189 R-SPO-9018745 https://reactome.org/PathwayBrowser/#/R-SPO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Schizosaccharomyces pombe 58189 R-SPO-9018747 https://reactome.org/PathwayBrowser/#/R-SPO-9018747 RHOQ GEFs activate RHOQ IEA Schizosaccharomyces pombe 58189 R-SPO-9018768 https://reactome.org/PathwayBrowser/#/R-SPO-9018768 RHOU auto-activates IEA Schizosaccharomyces pombe 58189 R-SPO-9018798 https://reactome.org/PathwayBrowser/#/R-SPO-9018798 RHOV binds GTP IEA Schizosaccharomyces pombe 58189 R-SPO-9018814 https://reactome.org/PathwayBrowser/#/R-SPO-9018814 RHOT1 hydrolyzes GTP IEA Schizosaccharomyces pombe 58189 R-SPO-9018826 https://reactome.org/PathwayBrowser/#/R-SPO-9018826 RHOT2 hydrolyzes GTP IEA Schizosaccharomyces pombe 58189 R-SPO-927789 https://reactome.org/PathwayBrowser/#/R-SPO-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Schizosaccharomyces pombe 58189 R-SPO-927836 https://reactome.org/PathwayBrowser/#/R-SPO-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Schizosaccharomyces pombe 58189 R-SPO-927889 https://reactome.org/PathwayBrowser/#/R-SPO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Schizosaccharomyces pombe 58189 R-SPO-9624845 https://reactome.org/PathwayBrowser/#/R-SPO-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Schizosaccharomyces pombe 58189 R-SPO-9624893 https://reactome.org/PathwayBrowser/#/R-SPO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Schizosaccharomyces pombe 58189 R-SPO-9639286 https://reactome.org/PathwayBrowser/#/R-SPO-9639286 RRAGC,D exchanges GTP for GDP IEA Schizosaccharomyces pombe 58189 R-SPO-9640167 https://reactome.org/PathwayBrowser/#/R-SPO-9640167 RRAGA,B exchanges GDP for GTP IEA Schizosaccharomyces pombe 58189 R-SPO-9640195 https://reactome.org/PathwayBrowser/#/R-SPO-9640195 RRAGA,B hydrolyzes GTP IEA Schizosaccharomyces pombe 58189 R-SPO-9645598 https://reactome.org/PathwayBrowser/#/R-SPO-9645598 RRAGC,D hydrolyzes GTP IEA Schizosaccharomyces pombe 58189 R-SPO-9645608 https://reactome.org/PathwayBrowser/#/R-SPO-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Schizosaccharomyces pombe 58189 R-SPO-9646468 https://reactome.org/PathwayBrowser/#/R-SPO-9646468 mTORC1 binds RHEB:GTP IEA Schizosaccharomyces pombe 58189 R-SPO-9693111 https://reactome.org/PathwayBrowser/#/R-SPO-9693111 RHOF auto-activates IEA Schizosaccharomyces pombe 58189 R-SPO-9693282 https://reactome.org/PathwayBrowser/#/R-SPO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Schizosaccharomyces pombe 58189 R-SPO-9726862 https://reactome.org/PathwayBrowser/#/R-SPO-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Schizosaccharomyces pombe 58189 R-SSC-1008248 https://reactome.org/PathwayBrowser/#/R-SSC-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Sus scrofa 58189 R-SSC-1028788 https://reactome.org/PathwayBrowser/#/R-SSC-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Sus scrofa 58189 R-SSC-110133 https://reactome.org/PathwayBrowser/#/R-SSC-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Sus scrofa 58189 R-SSC-111524 https://reactome.org/PathwayBrowser/#/R-SSC-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Sus scrofa 58189 R-SSC-112037 https://reactome.org/PathwayBrowser/#/R-SSC-112037 Inactivation of PLC beta IEA Sus scrofa 58189 R-SSC-114544 https://reactome.org/PathwayBrowser/#/R-SSC-114544 p115-RhoGEF activation of RHOA IEA Sus scrofa 58189 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa 58189 R-SSC-114558 https://reactome.org/PathwayBrowser/#/R-SSC-114558 Thrombin-activated PARs activate Gq IEA Sus scrofa 58189 R-SSC-1168636 https://reactome.org/PathwayBrowser/#/R-SSC-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Sus scrofa 58189 R-SSC-1250383 https://reactome.org/PathwayBrowser/#/R-SSC-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Sus scrofa 58189 R-SSC-1306972 https://reactome.org/PathwayBrowser/#/R-SSC-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Sus scrofa 58189 R-SSC-1433415 https://reactome.org/PathwayBrowser/#/R-SSC-1433415 Activation of RAC1 IEA Sus scrofa 58189 R-SSC-1433471 https://reactome.org/PathwayBrowser/#/R-SSC-1433471 Activation of RAS by p-KIT bound SOS1 IEA Sus scrofa 58189 R-SSC-156913 https://reactome.org/PathwayBrowser/#/R-SSC-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Sus scrofa 58189 R-SSC-162721 https://reactome.org/PathwayBrowser/#/R-SSC-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Sus scrofa 58189 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa 58189 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa 58189 R-SSC-165195 https://reactome.org/PathwayBrowser/#/R-SSC-165195 GTP loading by Rheb IEA Sus scrofa 58189 R-SSC-165680 https://reactome.org/PathwayBrowser/#/R-SSC-165680 Formation of active mTORC1 complex IEA Sus scrofa 58189 R-SSC-165692 https://reactome.org/PathwayBrowser/#/R-SSC-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Sus scrofa 58189 R-SSC-165718 https://reactome.org/PathwayBrowser/#/R-SSC-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Sus scrofa 58189 R-SSC-167408 https://reactome.org/PathwayBrowser/#/R-SSC-167408 The high affinity receptor complex binds to G-protein IEA Sus scrofa 58189 R-SSC-167415 https://reactome.org/PathwayBrowser/#/R-SSC-167415 G-protein alpha subunit is inactivated IEA Sus scrofa 58189 R-SSC-167419 https://reactome.org/PathwayBrowser/#/R-SSC-167419 The receptor:G-protein complex releases GDP IEA Sus scrofa 58189 R-SSC-167433 https://reactome.org/PathwayBrowser/#/R-SSC-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Sus scrofa 58189 R-SSC-169904 https://reactome.org/PathwayBrowser/#/R-SSC-169904 C3G stimulates nucleotide exchange on Rap1 IEA Sus scrofa 58189 R-SSC-170026 https://reactome.org/PathwayBrowser/#/R-SSC-170026 Protons are translocated from the intermembrane space to the matrix IEA Sus scrofa 58189 R-SSC-170666 https://reactome.org/PathwayBrowser/#/R-SSC-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa 58189 R-SSC-170674 https://reactome.org/PathwayBrowser/#/R-SSC-170674 Dissociation of the Gi alpha:G olf complex IEA Sus scrofa 58189 R-SSC-170677 https://reactome.org/PathwayBrowser/#/R-SSC-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Sus scrofa 58189 R-SSC-170685 https://reactome.org/PathwayBrowser/#/R-SSC-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa 58189 R-SSC-170686 https://reactome.org/PathwayBrowser/#/R-SSC-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Sus scrofa 58189 R-SSC-177938 https://reactome.org/PathwayBrowser/#/R-SSC-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Sus scrofa 58189 R-SSC-177945 https://reactome.org/PathwayBrowser/#/R-SSC-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Sus scrofa 58189 R-SSC-186834 https://reactome.org/PathwayBrowser/#/R-SSC-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Sus scrofa 58189 R-SSC-190520 https://reactome.org/PathwayBrowser/#/R-SSC-190520 Association of Golgi transport vesicles with microtubules IEA Sus scrofa 58189 R-SSC-193646 https://reactome.org/PathwayBrowser/#/R-SSC-193646 NGF binding to p75NTR inactivates RHOA IEA Sus scrofa 58189 R-SSC-193668 https://reactome.org/PathwayBrowser/#/R-SSC-193668 p75NTR and RHOA-GDI interact IEA Sus scrofa 58189 R-SSC-193696 https://reactome.org/PathwayBrowser/#/R-SSC-193696 The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA IEA Sus scrofa 58189 R-SSC-194518 https://reactome.org/PathwayBrowser/#/R-SSC-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth IEA Sus scrofa 58189 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa 58189 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa 58189 R-SSC-203977 https://reactome.org/PathwayBrowser/#/R-SSC-203977 SAR1 Activation And Membrane Binding IEA Sus scrofa 58189 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa 58189 R-SSC-210977 https://reactome.org/PathwayBrowser/#/R-SSC-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Sus scrofa 58189 R-SSC-2130641 https://reactome.org/PathwayBrowser/#/R-SSC-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Sus scrofa 58189 R-SSC-2130725 https://reactome.org/PathwayBrowser/#/R-SSC-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Sus scrofa 58189 R-SSC-2179407 https://reactome.org/PathwayBrowser/#/R-SSC-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Sus scrofa 58189 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa 58189 R-SSC-2424476 https://reactome.org/PathwayBrowser/#/R-SSC-2424476 Activation of RAC1 by VAV2/3 IEA Sus scrofa 58189 R-SSC-2424477 https://reactome.org/PathwayBrowser/#/R-SSC-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Sus scrofa 58189 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa 58189 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa 58189 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa 58189 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa 58189 R-SSC-2584246 https://reactome.org/PathwayBrowser/#/R-SSC-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Sus scrofa 58189 R-SSC-2730840 https://reactome.org/PathwayBrowser/#/R-SSC-2730840 Activation of RAC1 by VAV IEA Sus scrofa 58189 R-SSC-350769 https://reactome.org/PathwayBrowser/#/R-SSC-350769 trans-Golgi Network Coat Activation IEA Sus scrofa 58189 R-SSC-354173 https://reactome.org/PathwayBrowser/#/R-SSC-354173 Activation of Rap1 by cytosolic GEFs IEA Sus scrofa 58189 R-SSC-372819 https://reactome.org/PathwayBrowser/#/R-SSC-372819 PCK2 phosphorylates OA to yield PEP IEA Sus scrofa 58189 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa 58189 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 58189 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 58189 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 58189 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa 58189 R-SSC-380979 https://reactome.org/PathwayBrowser/#/R-SSC-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Sus scrofa 58189 R-SSC-381612 https://reactome.org/PathwayBrowser/#/R-SSC-381612 GLP1R binds GLP1 IEA Sus scrofa 58189 R-SSC-381727 https://reactome.org/PathwayBrowser/#/R-SSC-381727 RAP1A exchanges GDP for GTP IEA Sus scrofa 58189 R-SSC-389348 https://reactome.org/PathwayBrowser/#/R-SSC-389348 Activation of Rac1 by pVav1 IEA Sus scrofa 58189 R-SSC-389350 https://reactome.org/PathwayBrowser/#/R-SSC-389350 Activation of Cdc42 by pVav1 IEA Sus scrofa 58189 R-SSC-392054 https://reactome.org/PathwayBrowser/#/R-SSC-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Sus scrofa 58189 R-SSC-392195 https://reactome.org/PathwayBrowser/#/R-SSC-392195 Gi activation by P2Y purinoceptor 12 IEA Sus scrofa 58189 R-SSC-392513 https://reactome.org/PathwayBrowser/#/R-SSC-392513 Rap1 signal termination by Rap1GAPs IEA Sus scrofa 58189 R-SSC-3928592 https://reactome.org/PathwayBrowser/#/R-SSC-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Sus scrofa 58189 R-SSC-3928628 https://reactome.org/PathwayBrowser/#/R-SSC-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa 58189 R-SSC-3928642 https://reactome.org/PathwayBrowser/#/R-SSC-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa 58189 R-SSC-3928651 https://reactome.org/PathwayBrowser/#/R-SSC-3928651 NGEF exchanges GTP for GDP on RHOA IEA Sus scrofa 58189 R-SSC-392870 https://reactome.org/PathwayBrowser/#/R-SSC-392870 Gs activation by prostacyclin receptor IEA Sus scrofa 58189 R-SSC-3965444 https://reactome.org/PathwayBrowser/#/R-SSC-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Sus scrofa 58189 R-SSC-400092 https://reactome.org/PathwayBrowser/#/R-SSC-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Sus scrofa 58189 R-SSC-4093336 https://reactome.org/PathwayBrowser/#/R-SSC-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa 58189 R-SSC-4093339 https://reactome.org/PathwayBrowser/#/R-SSC-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Sus scrofa 58189 R-SSC-416559 https://reactome.org/PathwayBrowser/#/R-SSC-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Sus scrofa 58189 R-SSC-416588 https://reactome.org/PathwayBrowser/#/R-SSC-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Sus scrofa 58189 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa 58189 R-SSC-420883 https://reactome.org/PathwayBrowser/#/R-SSC-420883 Opsins act as GEFs for G alpha-t IEA Sus scrofa 58189 R-SSC-421831 https://reactome.org/PathwayBrowser/#/R-SSC-421831 trans-Golgi Network Coat Assembly IEA Sus scrofa 58189 R-SSC-421835 https://reactome.org/PathwayBrowser/#/R-SSC-421835 trans-Golgi Network Vesicle Scission IEA Sus scrofa 58189 R-SSC-428750 https://reactome.org/PathwayBrowser/#/R-SSC-428750 Gq activation by TP receptor IEA Sus scrofa 58189 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa 58189 R-SSC-432195 https://reactome.org/PathwayBrowser/#/R-SSC-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Sus scrofa 58189 R-SSC-432706 https://reactome.org/PathwayBrowser/#/R-SSC-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Sus scrofa 58189 R-SSC-432707 https://reactome.org/PathwayBrowser/#/R-SSC-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Sus scrofa 58189 R-SSC-442273 https://reactome.org/PathwayBrowser/#/R-SSC-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Sus scrofa 58189 R-SSC-442291 https://reactome.org/PathwayBrowser/#/R-SSC-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Sus scrofa 58189 R-SSC-445064 https://reactome.org/PathwayBrowser/#/R-SSC-445064 Activation of Rac1 by VAV2 IEA Sus scrofa 58189 R-SSC-446208 https://reactome.org/PathwayBrowser/#/R-SSC-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Sus scrofa 58189 R-SSC-446218 https://reactome.org/PathwayBrowser/#/R-SSC-446218 Addition of the first mannose to the N-glycan precursor by ALG1 IEA Sus scrofa 58189 R-SSC-447074 https://reactome.org/PathwayBrowser/#/R-SSC-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Sus scrofa 58189 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 58189 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 58189 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 58189 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 58189 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 58189 R-SSC-5218839 https://reactome.org/PathwayBrowser/#/R-SSC-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Sus scrofa 58189 R-SSC-5218850 https://reactome.org/PathwayBrowser/#/R-SSC-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa 58189 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP IEA Sus scrofa 58189 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa 58189 R-SSC-555065 https://reactome.org/PathwayBrowser/#/R-SSC-555065 Formation of clathrin coated vesicle IEA Sus scrofa 58189 R-SSC-5610733 https://reactome.org/PathwayBrowser/#/R-SSC-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Sus scrofa 58189 R-SSC-5610767 https://reactome.org/PathwayBrowser/#/R-SSC-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Sus scrofa 58189 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa 58189 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 58189 R-SSC-5618328 https://reactome.org/PathwayBrowser/#/R-SSC-5618328 ATAT acetylates microtubules IEA Sus scrofa 58189 R-SSC-5618331 https://reactome.org/PathwayBrowser/#/R-SSC-5618331 HDAC6 deacetylates microtubules IEA Sus scrofa 58189 R-SSC-5623508 https://reactome.org/PathwayBrowser/#/R-SSC-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Sus scrofa 58189 R-SSC-5623513 https://reactome.org/PathwayBrowser/#/R-SSC-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Sus scrofa 58189 R-SSC-5623519 https://reactome.org/PathwayBrowser/#/R-SSC-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Sus scrofa 58189 R-SSC-5623521 https://reactome.org/PathwayBrowser/#/R-SSC-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa 58189 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa 58189 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa 58189 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa 58189 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa 58189 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa 58189 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa 58189 R-SSC-5653957 https://reactome.org/PathwayBrowser/#/R-SSC-5653957 Rag dimer formation IEA Sus scrofa 58189 R-SSC-5653968 https://reactome.org/PathwayBrowser/#/R-SSC-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Sus scrofa 58189 R-SSC-5653974 https://reactome.org/PathwayBrowser/#/R-SSC-5653974 Ragulator binds Rag dimers IEA Sus scrofa 58189 R-SSC-5654392 https://reactome.org/PathwayBrowser/#/R-SSC-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-5654402 https://reactome.org/PathwayBrowser/#/R-SSC-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-5654413 https://reactome.org/PathwayBrowser/#/R-SSC-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-5654426 https://reactome.org/PathwayBrowser/#/R-SSC-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-5654600 https://reactome.org/PathwayBrowser/#/R-SSC-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-5654618 https://reactome.org/PathwayBrowser/#/R-SSC-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-5654647 https://reactome.org/PathwayBrowser/#/R-SSC-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-5654663 https://reactome.org/PathwayBrowser/#/R-SSC-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-5658231 https://reactome.org/PathwayBrowser/#/R-SSC-5658231 RAS GAPs stimulate RAS GTPase activity IEA Sus scrofa 58189 R-SSC-5665809 https://reactome.org/PathwayBrowser/#/R-SSC-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Sus scrofa 58189 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa 58189 R-SSC-5672010 https://reactome.org/PathwayBrowser/#/R-SSC-5672010 Active MTORC1 phosphorylates ULK1 IEA Sus scrofa 58189 R-SSC-5672017 https://reactome.org/PathwayBrowser/#/R-SSC-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Sus scrofa 58189 R-SSC-5672329 https://reactome.org/PathwayBrowser/#/R-SSC-5672329 IQGAP1 binds CLIP1 and microtubules IEA Sus scrofa 58189 R-SSC-5672817 https://reactome.org/PathwayBrowser/#/R-SSC-5672817 Active MTORC1 binds the ULK1 complex IEA Sus scrofa 58189 R-SSC-5672824 https://reactome.org/PathwayBrowser/#/R-SSC-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Sus scrofa 58189 R-SSC-5672828 https://reactome.org/PathwayBrowser/#/R-SSC-5672828 mTORC1 phosphorylates AKT1S1 IEA Sus scrofa 58189 R-SSC-5672843 https://reactome.org/PathwayBrowser/#/R-SSC-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Sus scrofa 58189 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-5673768 https://reactome.org/PathwayBrowser/#/R-SSC-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Sus scrofa 58189 R-SSC-5675790 https://reactome.org/PathwayBrowser/#/R-SSC-5675790 MTORC1 dissociates from ULK complex IEA Sus scrofa 58189 R-SSC-5693925 https://reactome.org/PathwayBrowser/#/R-SSC-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Sus scrofa 58189 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa 58189 R-SSC-5694527 https://reactome.org/PathwayBrowser/#/R-SSC-5694527 Loss of SAR1B GTPase IEA Sus scrofa 58189 R-SSC-6788611 https://reactome.org/PathwayBrowser/#/R-SSC-6788611 HYKK phosphorylates 5HLYS IEA Sus scrofa 58189 R-SSC-6807868 https://reactome.org/PathwayBrowser/#/R-SSC-6807868 GBF1 stimulates ARF nucleotide exchange IEA Sus scrofa 58189 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa 58189 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa 58189 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa 58189 R-SSC-6811418 https://reactome.org/PathwayBrowser/#/R-SSC-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Sus scrofa 58189 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa 58189 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa 58189 R-SSC-6814671 https://reactome.org/PathwayBrowser/#/R-SSC-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Sus scrofa 58189 R-SSC-70241 https://reactome.org/PathwayBrowser/#/R-SSC-70241 PCK1 phosphorylates OA to yield PEP IEA Sus scrofa 58189 R-SSC-71775 https://reactome.org/PathwayBrowser/#/R-SSC-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Sus scrofa 58189 R-SSC-72670 https://reactome.org/PathwayBrowser/#/R-SSC-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Sus scrofa 58189 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa 58189 R-SSC-72722 https://reactome.org/PathwayBrowser/#/R-SSC-72722 eIF2 activation IEA Sus scrofa 58189 R-SSC-73788 https://reactome.org/PathwayBrowser/#/R-SSC-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Sus scrofa 58189 R-SSC-749453 https://reactome.org/PathwayBrowser/#/R-SSC-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Sus scrofa 58189 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa 58189 R-SSC-8847534 https://reactome.org/PathwayBrowser/#/R-SSC-8847534 RAB43 hydrolyses GTP IEA Sus scrofa 58189 R-SSC-8847883 https://reactome.org/PathwayBrowser/#/R-SSC-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Sus scrofa 58189 R-SSC-8848618 https://reactome.org/PathwayBrowser/#/R-SSC-8848618 Activation of RAC1 by the PXN:CRK complex IEA Sus scrofa 58189 R-SSC-8849082 https://reactome.org/PathwayBrowser/#/R-SSC-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Sus scrofa 58189 R-SSC-8850040 https://reactome.org/PathwayBrowser/#/R-SSC-8850040 RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER IEA Sus scrofa 58189 R-SSC-8850041 https://reactome.org/PathwayBrowser/#/R-SSC-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 IEA Sus scrofa 58189 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58189 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58189 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58189 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58189 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58189 R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58189 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58189 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58189 R-SSC-8851827 https://reactome.org/PathwayBrowser/#/R-SSC-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Sus scrofa 58189 R-SSC-8851877 https://reactome.org/PathwayBrowser/#/R-SSC-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Sus scrofa 58189 R-SSC-8851899 https://reactome.org/PathwayBrowser/#/R-SSC-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Sus scrofa 58189 R-SSC-8852280 https://reactome.org/PathwayBrowser/#/R-SSC-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Sus scrofa 58189 R-SSC-8852298 https://reactome.org/PathwayBrowser/#/R-SSC-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Sus scrofa 58189 R-SSC-8852306 https://reactome.org/PathwayBrowser/#/R-SSC-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Sus scrofa 58189 R-SSC-8854173 https://reactome.org/PathwayBrowser/#/R-SSC-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Sus scrofa 58189 R-SSC-8854255 https://reactome.org/PathwayBrowser/#/R-SSC-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 58189 R-SSC-8854612 https://reactome.org/PathwayBrowser/#/R-SSC-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Sus scrofa 58189 R-SSC-8865774 https://reactome.org/PathwayBrowser/#/R-SSC-8865774 TTLLs polyglutamylate tubulin IEA Sus scrofa 58189 R-SSC-8867370 https://reactome.org/PathwayBrowser/#/R-SSC-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Sus scrofa 58189 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 58189 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa 58189 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa 58189 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 58189 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 58189 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa 58189 R-SSC-8875318 https://reactome.org/PathwayBrowser/#/R-SSC-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Sus scrofa 58189 R-SSC-8875320 https://reactome.org/PathwayBrowser/#/R-SSC-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Sus scrofa 58189 R-SSC-8875568 https://reactome.org/PathwayBrowser/#/R-SSC-8875568 RAPGEF1 activates RAP1 IEA Sus scrofa 58189 R-SSC-8875591 https://reactome.org/PathwayBrowser/#/R-SSC-8875591 DOCK7 activates RAC1 IEA Sus scrofa 58189 R-SSC-8876188 https://reactome.org/PathwayBrowser/#/R-SSC-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Sus scrofa 58189 R-SSC-8876190 https://reactome.org/PathwayBrowser/#/R-SSC-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Sus scrofa 58189 R-SSC-8876191 https://reactome.org/PathwayBrowser/#/R-SSC-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Sus scrofa 58189 R-SSC-8876454 https://reactome.org/PathwayBrowser/#/R-SSC-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Sus scrofa 58189 R-SSC-8876615 https://reactome.org/PathwayBrowser/#/R-SSC-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Sus scrofa 58189 R-SSC-8877308 https://reactome.org/PathwayBrowser/#/R-SSC-8877308 MADD exchanges GTP for GDP on RAB27 IEA Sus scrofa 58189 R-SSC-8877311 https://reactome.org/PathwayBrowser/#/R-SSC-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Sus scrofa 58189 R-SSC-8877451 https://reactome.org/PathwayBrowser/#/R-SSC-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Sus scrofa 58189 R-SSC-8877612 https://reactome.org/PathwayBrowser/#/R-SSC-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Sus scrofa 58189 R-SSC-8877760 https://reactome.org/PathwayBrowser/#/R-SSC-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Sus scrofa 58189 R-SSC-8877813 https://reactome.org/PathwayBrowser/#/R-SSC-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Sus scrofa 58189 R-SSC-8877998 https://reactome.org/PathwayBrowser/#/R-SSC-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Sus scrofa 58189 R-SSC-8938815 https://reactome.org/PathwayBrowser/#/R-SSC-8938815 RNF152 polyubiquitinates RRAGA IEA Sus scrofa 58189 R-SSC-8938829 https://reactome.org/PathwayBrowser/#/R-SSC-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 IEA Sus scrofa 58189 R-SSC-8941613 https://reactome.org/PathwayBrowser/#/R-SSC-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-8941618 https://reactome.org/PathwayBrowser/#/R-SSC-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-8941623 https://reactome.org/PathwayBrowser/#/R-SSC-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-8941628 https://reactome.org/PathwayBrowser/#/R-SSC-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa 58189 R-SSC-8944454 https://reactome.org/PathwayBrowser/#/R-SSC-8944454 mTORC1 phosphorylates MAF1 IEA Sus scrofa 58189 R-SSC-8944457 https://reactome.org/PathwayBrowser/#/R-SSC-8944457 MAF1 translocates to the nucleus IEA Sus scrofa 58189 R-SSC-8951498 https://reactome.org/PathwayBrowser/#/R-SSC-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Sus scrofa 58189 R-SSC-8951586 https://reactome.org/PathwayBrowser/#/R-SSC-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Sus scrofa 58189 R-SSC-8952716 https://reactome.org/PathwayBrowser/#/R-SSC-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Sus scrofa 58189 R-SSC-8952726 https://reactome.org/PathwayBrowser/#/R-SSC-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Sus scrofa 58189 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa 58189 R-SSC-8981353 https://reactome.org/PathwayBrowser/#/R-SSC-8981353 RASA1 stimulates RAS GTPase activity IEA Sus scrofa 58189 R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa 58189 R-SSC-8982012 https://reactome.org/PathwayBrowser/#/R-SSC-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Sus scrofa 58189 R-SSC-8982018 https://reactome.org/PathwayBrowser/#/R-SSC-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Sus scrofa 58189 R-SSC-8982020 https://reactome.org/PathwayBrowser/#/R-SSC-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Sus scrofa 58189 R-SSC-8982021 https://reactome.org/PathwayBrowser/#/R-SSC-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Sus scrofa 58189 R-SSC-8982025 https://reactome.org/PathwayBrowser/#/R-SSC-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Sus scrofa 58189 R-SSC-8982026 https://reactome.org/PathwayBrowser/#/R-SSC-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Sus scrofa 58189 R-SSC-8985594 https://reactome.org/PathwayBrowser/#/R-SSC-8985594 MYO9B inactivates RHOA IEA Sus scrofa 58189 R-SSC-9012761 https://reactome.org/PathwayBrowser/#/R-SSC-9012761 The p75NTR:NgR:MDGI binds RHOA-GDI IEA Sus scrofa 58189 R-SSC-9012835 https://reactome.org/PathwayBrowser/#/R-SSC-9012835 GDIs block activation of RHOA IEA Sus scrofa 58189 R-SSC-9013021 https://reactome.org/PathwayBrowser/#/R-SSC-9013021 GDIs block activation of RHOB IEA Sus scrofa 58189 R-SSC-9013022 https://reactome.org/PathwayBrowser/#/R-SSC-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Sus scrofa 58189 R-SSC-9013023 https://reactome.org/PathwayBrowser/#/R-SSC-9013023 RHOB GEFs activate RHOB IEA Sus scrofa 58189 R-SSC-9013108 https://reactome.org/PathwayBrowser/#/R-SSC-9013108 GDIs block activation of RHOC IEA Sus scrofa 58189 R-SSC-9013109 https://reactome.org/PathwayBrowser/#/R-SSC-9013109 RHOC GEFs activate RHOC IEA Sus scrofa 58189 R-SSC-9013111 https://reactome.org/PathwayBrowser/#/R-SSC-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Sus scrofa 58189 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa 58189 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa 58189 R-SSC-9013147 https://reactome.org/PathwayBrowser/#/R-SSC-9013147 RAC1 GDIs block activation of RAC1 IEA Sus scrofa 58189 R-SSC-9013158 https://reactome.org/PathwayBrowser/#/R-SSC-9013158 CDC42 GDIs block activation of CDC42 IEA Sus scrofa 58189 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa 58189 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa 58189 R-SSC-9013435 https://reactome.org/PathwayBrowser/#/R-SSC-9013435 RHOD auto-activates IEA Sus scrofa 58189 R-SSC-9013437 https://reactome.org/PathwayBrowser/#/R-SSC-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Sus scrofa 58189 R-SSC-9014293 https://reactome.org/PathwayBrowser/#/R-SSC-9014293 RAC2 GDIs block activation of RAC2 IEA Sus scrofa 58189 R-SSC-9014295 https://reactome.org/PathwayBrowser/#/R-SSC-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Sus scrofa 58189 R-SSC-9014296 https://reactome.org/PathwayBrowser/#/R-SSC-9014296 RAC2 GEFs activate RAC2 IEA Sus scrofa 58189 R-SSC-9014433 https://reactome.org/PathwayBrowser/#/R-SSC-9014433 RHOG GEFs activate RHOG IEA Sus scrofa 58189 R-SSC-9014434 https://reactome.org/PathwayBrowser/#/R-SSC-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Sus scrofa 58189 R-SSC-9014456 https://reactome.org/PathwayBrowser/#/R-SSC-9014456 GDIs block activation of RHOG IEA Sus scrofa 58189 R-SSC-9017488 https://reactome.org/PathwayBrowser/#/R-SSC-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Sus scrofa 58189 R-SSC-9017491 https://reactome.org/PathwayBrowser/#/R-SSC-9017491 RHOJ GEFs activate RHOJ IEA Sus scrofa 58189 R-SSC-9018745 https://reactome.org/PathwayBrowser/#/R-SSC-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Sus scrofa 58189 R-SSC-9018747 https://reactome.org/PathwayBrowser/#/R-SSC-9018747 RHOQ GEFs activate RHOQ IEA Sus scrofa 58189 R-SSC-9018768 https://reactome.org/PathwayBrowser/#/R-SSC-9018768 RHOU auto-activates IEA Sus scrofa 58189 R-SSC-9018798 https://reactome.org/PathwayBrowser/#/R-SSC-9018798 RHOV binds GTP IEA Sus scrofa 58189 R-SSC-9018804 https://reactome.org/PathwayBrowser/#/R-SSC-9018804 RAC3 GEFs activate RAC3 IEA Sus scrofa 58189 R-SSC-9018806 https://reactome.org/PathwayBrowser/#/R-SSC-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Sus scrofa 58189 R-SSC-9018807 https://reactome.org/PathwayBrowser/#/R-SSC-9018807 RAC3 GDIs block activation of RAC3 IEA Sus scrofa 58189 R-SSC-9018814 https://reactome.org/PathwayBrowser/#/R-SSC-9018814 RHOT1 hydrolyzes GTP IEA Sus scrofa 58189 R-SSC-9018826 https://reactome.org/PathwayBrowser/#/R-SSC-9018826 RHOT2 hydrolyzes GTP IEA Sus scrofa 58189 R-SSC-9032798 https://reactome.org/PathwayBrowser/#/R-SSC-9032798 DOCK3 activates RAC1 IEA Sus scrofa 58189 R-SSC-9033949 https://reactome.org/PathwayBrowser/#/R-SSC-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Sus scrofa 58189 R-SSC-9036301 https://reactome.org/PathwayBrowser/#/R-SSC-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Sus scrofa 58189 R-SSC-9036307 https://reactome.org/PathwayBrowser/#/R-SSC-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Sus scrofa 58189 R-SSC-9036987 https://reactome.org/PathwayBrowser/#/R-SSC-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Sus scrofa 58189 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa 58189 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa 58189 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa 58189 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa 58189 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa 58189 R-SSC-939265 https://reactome.org/PathwayBrowser/#/R-SSC-939265 Activation of Rap1 by membrane-associated GEFs IEA Sus scrofa 58189 R-SSC-9603982 https://reactome.org/PathwayBrowser/#/R-SSC-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Sus scrofa 58189 R-SSC-9603983 https://reactome.org/PathwayBrowser/#/R-SSC-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Sus scrofa 58189 R-SSC-9603984 https://reactome.org/PathwayBrowser/#/R-SSC-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Sus scrofa 58189 R-SSC-9603986 https://reactome.org/PathwayBrowser/#/R-SSC-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Sus scrofa 58189 R-SSC-9605609 https://reactome.org/PathwayBrowser/#/R-SSC-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Sus scrofa 58189 R-SSC-9605644 https://reactome.org/PathwayBrowser/#/R-SSC-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Sus scrofa 58189 R-SSC-9605682 https://reactome.org/PathwayBrowser/#/R-SSC-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Sus scrofa 58189 R-SSC-9607304 https://reactome.org/PathwayBrowser/#/R-SSC-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Sus scrofa 58189 R-SSC-9624845 https://reactome.org/PathwayBrowser/#/R-SSC-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Sus scrofa 58189 R-SSC-9624893 https://reactome.org/PathwayBrowser/#/R-SSC-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Sus scrofa 58189 R-SSC-9632906 https://reactome.org/PathwayBrowser/#/R-SSC-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Sus scrofa 58189 R-SSC-9632918 https://reactome.org/PathwayBrowser/#/R-SSC-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Sus scrofa 58189 R-SSC-9639286 https://reactome.org/PathwayBrowser/#/R-SSC-9639286 RRAGC,D exchanges GTP for GDP IEA Sus scrofa 58189 R-SSC-9640167 https://reactome.org/PathwayBrowser/#/R-SSC-9640167 RRAGA,B exchanges GDP for GTP IEA Sus scrofa 58189 R-SSC-9640168 https://reactome.org/PathwayBrowser/#/R-SSC-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Sus scrofa 58189 R-SSC-9640175 https://reactome.org/PathwayBrowser/#/R-SSC-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Sus scrofa 58189 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa 58189 R-SSC-9645598 https://reactome.org/PathwayBrowser/#/R-SSC-9645598 RRAGC,D hydrolyzes GTP IEA Sus scrofa 58189 R-SSC-9645608 https://reactome.org/PathwayBrowser/#/R-SSC-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Sus scrofa 58189 R-SSC-9646468 https://reactome.org/PathwayBrowser/#/R-SSC-9646468 mTORC1 binds RHEB:GTP IEA Sus scrofa 58189 R-SSC-9646679 https://reactome.org/PathwayBrowser/#/R-SSC-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Sus scrofa 58189 R-SSC-9646685 https://reactome.org/PathwayBrowser/#/R-SSC-9646685 Aggresome dissociates from dynein and microtubule IEA Sus scrofa 58189 R-SSC-9648017 https://reactome.org/PathwayBrowser/#/R-SSC-9648017 EML4 binds to microtubules IEA Sus scrofa 58189 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa 58189 R-SSC-9649733 https://reactome.org/PathwayBrowser/#/R-SSC-9649733 mature p21 RAS binds GDP IEA Sus scrofa 58189 R-SSC-9649735 https://reactome.org/PathwayBrowser/#/R-SSC-9649735 Intrinsic nucleotide exchange on RAS IEA Sus scrofa 58189 R-SSC-9649736 https://reactome.org/PathwayBrowser/#/R-SSC-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Sus scrofa 58189 R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa 58189 R-SSC-9693111 https://reactome.org/PathwayBrowser/#/R-SSC-9693111 RHOF auto-activates IEA Sus scrofa 58189 R-SSC-9693282 https://reactome.org/PathwayBrowser/#/R-SSC-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Sus scrofa 58189 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 58189 R-SSC-9717206 https://reactome.org/PathwayBrowser/#/R-SSC-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Sus scrofa 58189 R-SSC-9726862 https://reactome.org/PathwayBrowser/#/R-SSC-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Sus scrofa 58189 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa 58189 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 58189 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 58189 R-SSC-9751201 https://reactome.org/PathwayBrowser/#/R-SSC-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Sus scrofa 58189 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa 58189 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa 58189 R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa 58189 R-SSC-9836404 https://reactome.org/PathwayBrowser/#/R-SSC-9836404 p-PKR dimer phosphorylates MAPT IEA Sus scrofa 58189 R-SSC-9846332 https://reactome.org/PathwayBrowser/#/R-SSC-9846332 FUT1,2 transfer fucose to gangliosides IEA Sus scrofa 58189 R-XTR-1028788 https://reactome.org/PathwayBrowser/#/R-XTR-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Xenopus tropicalis 58189 R-XTR-110133 https://reactome.org/PathwayBrowser/#/R-XTR-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Xenopus tropicalis 58189 R-XTR-111524 https://reactome.org/PathwayBrowser/#/R-XTR-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Xenopus tropicalis 58189 R-XTR-112037 https://reactome.org/PathwayBrowser/#/R-XTR-112037 Inactivation of PLC beta IEA Xenopus tropicalis 58189 R-XTR-114552 https://reactome.org/PathwayBrowser/#/R-XTR-114552 Thrombin-activated PARs activate G12/13 IEA Xenopus tropicalis 58189 R-XTR-114558 https://reactome.org/PathwayBrowser/#/R-XTR-114558 Thrombin-activated PARs activate Gq IEA Xenopus tropicalis 58189 R-XTR-1168636 https://reactome.org/PathwayBrowser/#/R-XTR-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Xenopus tropicalis 58189 R-XTR-1250383 https://reactome.org/PathwayBrowser/#/R-XTR-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Xenopus tropicalis 58189 R-XTR-1306972 https://reactome.org/PathwayBrowser/#/R-XTR-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Xenopus tropicalis 58189 R-XTR-1433415 https://reactome.org/PathwayBrowser/#/R-XTR-1433415 Activation of RAC1 IEA Xenopus tropicalis 58189 R-XTR-1433471 https://reactome.org/PathwayBrowser/#/R-XTR-1433471 Activation of RAS by p-KIT bound SOS1 IEA Xenopus tropicalis 58189 R-XTR-162721 https://reactome.org/PathwayBrowser/#/R-XTR-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Xenopus tropicalis 58189 R-XTR-1638803 https://reactome.org/PathwayBrowser/#/R-XTR-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Xenopus tropicalis 58189 R-XTR-1638821 https://reactome.org/PathwayBrowser/#/R-XTR-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Xenopus tropicalis 58189 R-XTR-165195 https://reactome.org/PathwayBrowser/#/R-XTR-165195 GTP loading by Rheb IEA Xenopus tropicalis 58189 R-XTR-165680 https://reactome.org/PathwayBrowser/#/R-XTR-165680 Formation of active mTORC1 complex IEA Xenopus tropicalis 58189 R-XTR-167408 https://reactome.org/PathwayBrowser/#/R-XTR-167408 The high affinity receptor complex binds to G-protein IEA Xenopus tropicalis 58189 R-XTR-167415 https://reactome.org/PathwayBrowser/#/R-XTR-167415 G-protein alpha subunit is inactivated IEA Xenopus tropicalis 58189 R-XTR-167419 https://reactome.org/PathwayBrowser/#/R-XTR-167419 The receptor:G-protein complex releases GDP IEA Xenopus tropicalis 58189 R-XTR-167433 https://reactome.org/PathwayBrowser/#/R-XTR-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Xenopus tropicalis 58189 R-XTR-169904 https://reactome.org/PathwayBrowser/#/R-XTR-169904 C3G stimulates nucleotide exchange on Rap1 IEA Xenopus tropicalis 58189 R-XTR-170026 https://reactome.org/PathwayBrowser/#/R-XTR-170026 Protons are translocated from the intermembrane space to the matrix IEA Xenopus tropicalis 58189 R-XTR-170666 https://reactome.org/PathwayBrowser/#/R-XTR-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Xenopus tropicalis 58189 R-XTR-170674 https://reactome.org/PathwayBrowser/#/R-XTR-170674 Dissociation of the Gi alpha:G olf complex IEA Xenopus tropicalis 58189 R-XTR-170677 https://reactome.org/PathwayBrowser/#/R-XTR-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Xenopus tropicalis 58189 R-XTR-170685 https://reactome.org/PathwayBrowser/#/R-XTR-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Xenopus tropicalis 58189 R-XTR-170686 https://reactome.org/PathwayBrowser/#/R-XTR-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Xenopus tropicalis 58189 R-XTR-177938 https://reactome.org/PathwayBrowser/#/R-XTR-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Xenopus tropicalis 58189 R-XTR-177945 https://reactome.org/PathwayBrowser/#/R-XTR-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Xenopus tropicalis 58189 R-XTR-186834 https://reactome.org/PathwayBrowser/#/R-XTR-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Xenopus tropicalis 58189 R-XTR-190520 https://reactome.org/PathwayBrowser/#/R-XTR-190520 Association of Golgi transport vesicles with microtubules IEA Xenopus tropicalis 58189 R-XTR-193646 https://reactome.org/PathwayBrowser/#/R-XTR-193646 NGF binding to p75NTR inactivates RHOA IEA Xenopus tropicalis 58189 R-XTR-193668 https://reactome.org/PathwayBrowser/#/R-XTR-193668 p75NTR and RHOA-GDI interact IEA Xenopus tropicalis 58189 R-XTR-203977 https://reactome.org/PathwayBrowser/#/R-XTR-203977 SAR1 Activation And Membrane Binding IEA Xenopus tropicalis 58189 R-XTR-205039 https://reactome.org/PathwayBrowser/#/R-XTR-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Xenopus tropicalis 58189 R-XTR-210977 https://reactome.org/PathwayBrowser/#/R-XTR-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Xenopus tropicalis 58189 R-XTR-2130641 https://reactome.org/PathwayBrowser/#/R-XTR-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Xenopus tropicalis 58189 R-XTR-2179407 https://reactome.org/PathwayBrowser/#/R-XTR-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Xenopus tropicalis 58189 R-XTR-2424476 https://reactome.org/PathwayBrowser/#/R-XTR-2424476 Activation of RAC1 by VAV2/3 IEA Xenopus tropicalis 58189 R-XTR-2424477 https://reactome.org/PathwayBrowser/#/R-XTR-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Xenopus tropicalis 58189 R-XTR-2467809 https://reactome.org/PathwayBrowser/#/R-XTR-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Xenopus tropicalis 58189 R-XTR-2468287 https://reactome.org/PathwayBrowser/#/R-XTR-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Xenopus tropicalis 58189 R-XTR-2484822 https://reactome.org/PathwayBrowser/#/R-XTR-2484822 Kinetochore assembly IEA Xenopus tropicalis 58189 R-XTR-2584246 https://reactome.org/PathwayBrowser/#/R-XTR-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Xenopus tropicalis 58189 R-XTR-2730840 https://reactome.org/PathwayBrowser/#/R-XTR-2730840 Activation of RAC1 by VAV IEA Xenopus tropicalis 58189 R-XTR-354173 https://reactome.org/PathwayBrowser/#/R-XTR-354173 Activation of Rap1 by cytosolic GEFs IEA Xenopus tropicalis 58189 R-XTR-375302 https://reactome.org/PathwayBrowser/#/R-XTR-375302 Kinetochore capture of astral microtubules IEA Xenopus tropicalis 58189 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 58189 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 58189 R-XTR-380316 https://reactome.org/PathwayBrowser/#/R-XTR-380316 Association of NuMA with microtubules IEA Xenopus tropicalis 58189 R-XTR-380979 https://reactome.org/PathwayBrowser/#/R-XTR-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Xenopus tropicalis 58189 R-XTR-381727 https://reactome.org/PathwayBrowser/#/R-XTR-381727 RAP1A exchanges GDP for GTP IEA Xenopus tropicalis 58189 R-XTR-389348 https://reactome.org/PathwayBrowser/#/R-XTR-389348 Activation of Rac1 by pVav1 IEA Xenopus tropicalis 58189 R-XTR-389350 https://reactome.org/PathwayBrowser/#/R-XTR-389350 Activation of Cdc42 by pVav1 IEA Xenopus tropicalis 58189 R-XTR-392054 https://reactome.org/PathwayBrowser/#/R-XTR-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Xenopus tropicalis 58189 R-XTR-392195 https://reactome.org/PathwayBrowser/#/R-XTR-392195 Gi activation by P2Y purinoceptor 12 IEA Xenopus tropicalis 58189 R-XTR-392513 https://reactome.org/PathwayBrowser/#/R-XTR-392513 Rap1 signal termination by Rap1GAPs IEA Xenopus tropicalis 58189 R-XTR-3928592 https://reactome.org/PathwayBrowser/#/R-XTR-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Xenopus tropicalis 58189 R-XTR-3928628 https://reactome.org/PathwayBrowser/#/R-XTR-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Xenopus tropicalis 58189 R-XTR-3928642 https://reactome.org/PathwayBrowser/#/R-XTR-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Xenopus tropicalis 58189 R-XTR-3928651 https://reactome.org/PathwayBrowser/#/R-XTR-3928651 NGEF exchanges GTP for GDP on RHOA IEA Xenopus tropicalis 58189 R-XTR-392870 https://reactome.org/PathwayBrowser/#/R-XTR-392870 Gs activation by prostacyclin receptor IEA Xenopus tropicalis 58189 R-XTR-3965444 https://reactome.org/PathwayBrowser/#/R-XTR-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-400092 https://reactome.org/PathwayBrowser/#/R-XTR-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Xenopus tropicalis 58189 R-XTR-4093336 https://reactome.org/PathwayBrowser/#/R-XTR-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Xenopus tropicalis 58189 R-XTR-4093339 https://reactome.org/PathwayBrowser/#/R-XTR-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Xenopus tropicalis 58189 R-XTR-416559 https://reactome.org/PathwayBrowser/#/R-XTR-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Xenopus tropicalis 58189 R-XTR-416588 https://reactome.org/PathwayBrowser/#/R-XTR-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Xenopus tropicalis 58189 R-XTR-418850 https://reactome.org/PathwayBrowser/#/R-XTR-418850 Activation of Cdc42 IEA Xenopus tropicalis 58189 R-XTR-418856 https://reactome.org/PathwayBrowser/#/R-XTR-418856 Activation of Rac1 IEA Xenopus tropicalis 58189 R-XTR-419166 https://reactome.org/PathwayBrowser/#/R-XTR-419166 GEFs activate RhoA,B,C IEA Xenopus tropicalis 58189 R-XTR-420883 https://reactome.org/PathwayBrowser/#/R-XTR-420883 Opsins act as GEFs for G alpha-t IEA Xenopus tropicalis 58189 R-XTR-421835 https://reactome.org/PathwayBrowser/#/R-XTR-421835 trans-Golgi Network Vesicle Scission IEA Xenopus tropicalis 58189 R-XTR-428750 https://reactome.org/PathwayBrowser/#/R-XTR-428750 Gq activation by TP receptor IEA Xenopus tropicalis 58189 R-XTR-428917 https://reactome.org/PathwayBrowser/#/R-XTR-428917 G13 activation by TP receptor IEA Xenopus tropicalis 58189 R-XTR-432195 https://reactome.org/PathwayBrowser/#/R-XTR-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Xenopus tropicalis 58189 R-XTR-432707 https://reactome.org/PathwayBrowser/#/R-XTR-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Xenopus tropicalis 58189 R-XTR-442273 https://reactome.org/PathwayBrowser/#/R-XTR-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Xenopus tropicalis 58189 R-XTR-442314 https://reactome.org/PathwayBrowser/#/R-XTR-442314 VAV3 is a GEF for Rho/Rac family kinases IEA Xenopus tropicalis 58189 R-XTR-445071 https://reactome.org/PathwayBrowser/#/R-XTR-445071 Reinsertion of L1 into the plasma membrane IEA Xenopus tropicalis 58189 R-XTR-446208 https://reactome.org/PathwayBrowser/#/R-XTR-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Xenopus tropicalis 58189 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 58189 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 58189 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 58189 R-XTR-5218839 https://reactome.org/PathwayBrowser/#/R-XTR-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Xenopus tropicalis 58189 R-XTR-5218850 https://reactome.org/PathwayBrowser/#/R-XTR-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Xenopus tropicalis 58189 R-XTR-5617816 https://reactome.org/PathwayBrowser/#/R-XTR-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Xenopus tropicalis 58189 R-XTR-5618328 https://reactome.org/PathwayBrowser/#/R-XTR-5618328 ATAT acetylates microtubules IEA Xenopus tropicalis 58189 R-XTR-5623519 https://reactome.org/PathwayBrowser/#/R-XTR-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Xenopus tropicalis 58189 R-XTR-5623521 https://reactome.org/PathwayBrowser/#/R-XTR-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Xenopus tropicalis 58189 R-XTR-5653957 https://reactome.org/PathwayBrowser/#/R-XTR-5653957 Rag dimer formation IEA Xenopus tropicalis 58189 R-XTR-5653974 https://reactome.org/PathwayBrowser/#/R-XTR-5653974 Ragulator binds Rag dimers IEA Xenopus tropicalis 58189 R-XTR-5654392 https://reactome.org/PathwayBrowser/#/R-XTR-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-5654402 https://reactome.org/PathwayBrowser/#/R-XTR-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-5654413 https://reactome.org/PathwayBrowser/#/R-XTR-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-5654426 https://reactome.org/PathwayBrowser/#/R-XTR-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-5654600 https://reactome.org/PathwayBrowser/#/R-XTR-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-5654618 https://reactome.org/PathwayBrowser/#/R-XTR-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-5654647 https://reactome.org/PathwayBrowser/#/R-XTR-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-5654663 https://reactome.org/PathwayBrowser/#/R-XTR-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-5666169 https://reactome.org/PathwayBrowser/#/R-XTR-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Xenopus tropicalis 58189 R-XTR-5672010 https://reactome.org/PathwayBrowser/#/R-XTR-5672010 Active MTORC1 phosphorylates ULK1 IEA Xenopus tropicalis 58189 R-XTR-5672017 https://reactome.org/PathwayBrowser/#/R-XTR-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Xenopus tropicalis 58189 R-XTR-5672817 https://reactome.org/PathwayBrowser/#/R-XTR-5672817 Active MTORC1 binds the ULK1 complex IEA Xenopus tropicalis 58189 R-XTR-5672824 https://reactome.org/PathwayBrowser/#/R-XTR-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Xenopus tropicalis 58189 R-XTR-5672828 https://reactome.org/PathwayBrowser/#/R-XTR-5672828 mTORC1 phosphorylates AKT1S1 IEA Xenopus tropicalis 58189 R-XTR-5672843 https://reactome.org/PathwayBrowser/#/R-XTR-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Xenopus tropicalis 58189 R-XTR-5672965 https://reactome.org/PathwayBrowser/#/R-XTR-5672965 RAS GEFs promote RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-5675790 https://reactome.org/PathwayBrowser/#/R-XTR-5675790 MTORC1 dissociates from ULK complex IEA Xenopus tropicalis 58189 R-XTR-5693925 https://reactome.org/PathwayBrowser/#/R-XTR-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Xenopus tropicalis 58189 R-XTR-5694409 https://reactome.org/PathwayBrowser/#/R-XTR-5694409 Nucleotide exchange on RAB1 IEA Xenopus tropicalis 58189 R-XTR-5694527 https://reactome.org/PathwayBrowser/#/R-XTR-5694527 Loss of SAR1B GTPase IEA Xenopus tropicalis 58189 R-XTR-6788611 https://reactome.org/PathwayBrowser/#/R-XTR-6788611 HYKK phosphorylates 5HLYS IEA Xenopus tropicalis 58189 R-XTR-6809003 https://reactome.org/PathwayBrowser/#/R-XTR-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Xenopus tropicalis 58189 R-XTR-6811426 https://reactome.org/PathwayBrowser/#/R-XTR-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Xenopus tropicalis 58189 R-XTR-70241 https://reactome.org/PathwayBrowser/#/R-XTR-70241 PCK1 phosphorylates OA to yield PEP IEA Xenopus tropicalis 58189 R-XTR-71775 https://reactome.org/PathwayBrowser/#/R-XTR-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Xenopus tropicalis 58189 R-XTR-72671 https://reactome.org/PathwayBrowser/#/R-XTR-72671 eIF5B:GTP is hydrolyzed and released IEA Xenopus tropicalis 58189 R-XTR-73788 https://reactome.org/PathwayBrowser/#/R-XTR-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Xenopus tropicalis 58189 R-XTR-749453 https://reactome.org/PathwayBrowser/#/R-XTR-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Xenopus tropicalis 58189 R-XTR-751029 https://reactome.org/PathwayBrowser/#/R-XTR-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Xenopus tropicalis 58189 R-XTR-8847883 https://reactome.org/PathwayBrowser/#/R-XTR-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Xenopus tropicalis 58189 R-XTR-8848618 https://reactome.org/PathwayBrowser/#/R-XTR-8848618 Activation of RAC1 by the PXN:CRK complex IEA Xenopus tropicalis 58189 R-XTR-8849082 https://reactome.org/PathwayBrowser/#/R-XTR-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Xenopus tropicalis 58189 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58189 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58189 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58189 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58189 R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58189 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58189 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58189 R-XTR-8851827 https://reactome.org/PathwayBrowser/#/R-XTR-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Xenopus tropicalis 58189 R-XTR-8851877 https://reactome.org/PathwayBrowser/#/R-XTR-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Xenopus tropicalis 58189 R-XTR-8851899 https://reactome.org/PathwayBrowser/#/R-XTR-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Xenopus tropicalis 58189 R-XTR-8852280 https://reactome.org/PathwayBrowser/#/R-XTR-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Xenopus tropicalis 58189 R-XTR-8852298 https://reactome.org/PathwayBrowser/#/R-XTR-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Xenopus tropicalis 58189 R-XTR-8852306 https://reactome.org/PathwayBrowser/#/R-XTR-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Xenopus tropicalis 58189 R-XTR-8854173 https://reactome.org/PathwayBrowser/#/R-XTR-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Xenopus tropicalis 58189 R-XTR-8854255 https://reactome.org/PathwayBrowser/#/R-XTR-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 58189 R-XTR-8854612 https://reactome.org/PathwayBrowser/#/R-XTR-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Xenopus tropicalis 58189 R-XTR-8865774 https://reactome.org/PathwayBrowser/#/R-XTR-8865774 TTLLs polyglutamylate tubulin IEA Xenopus tropicalis 58189 R-XTR-8867370 https://reactome.org/PathwayBrowser/#/R-XTR-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Xenopus tropicalis 58189 R-XTR-8875318 https://reactome.org/PathwayBrowser/#/R-XTR-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Xenopus tropicalis 58189 R-XTR-8875568 https://reactome.org/PathwayBrowser/#/R-XTR-8875568 RAPGEF1 activates RAP1 IEA Xenopus tropicalis 58189 R-XTR-8875591 https://reactome.org/PathwayBrowser/#/R-XTR-8875591 DOCK7 activates RAC1 IEA Xenopus tropicalis 58189 R-XTR-8876188 https://reactome.org/PathwayBrowser/#/R-XTR-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Xenopus tropicalis 58189 R-XTR-8876190 https://reactome.org/PathwayBrowser/#/R-XTR-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Xenopus tropicalis 58189 R-XTR-8876191 https://reactome.org/PathwayBrowser/#/R-XTR-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Xenopus tropicalis 58189 R-XTR-8876615 https://reactome.org/PathwayBrowser/#/R-XTR-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Xenopus tropicalis 58189 R-XTR-8877612 https://reactome.org/PathwayBrowser/#/R-XTR-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Xenopus tropicalis 58189 R-XTR-8938815 https://reactome.org/PathwayBrowser/#/R-XTR-8938815 RNF152 polyubiquitinates RRAGA IEA Xenopus tropicalis 58189 R-XTR-8938829 https://reactome.org/PathwayBrowser/#/R-XTR-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 IEA Xenopus tropicalis 58189 R-XTR-8941613 https://reactome.org/PathwayBrowser/#/R-XTR-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-8941618 https://reactome.org/PathwayBrowser/#/R-XTR-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-8941623 https://reactome.org/PathwayBrowser/#/R-XTR-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-8941628 https://reactome.org/PathwayBrowser/#/R-XTR-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Xenopus tropicalis 58189 R-XTR-8951498 https://reactome.org/PathwayBrowser/#/R-XTR-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Xenopus tropicalis 58189 R-XTR-8951586 https://reactome.org/PathwayBrowser/#/R-XTR-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Xenopus tropicalis 58189 R-XTR-8952716 https://reactome.org/PathwayBrowser/#/R-XTR-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Xenopus tropicalis 58189 R-XTR-8952726 https://reactome.org/PathwayBrowser/#/R-XTR-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Xenopus tropicalis 58189 R-XTR-8980691 https://reactome.org/PathwayBrowser/#/R-XTR-8980691 RHOA GEFs activate RHOA IEA Xenopus tropicalis 58189 R-XTR-8981353 https://reactome.org/PathwayBrowser/#/R-XTR-8981353 RASA1 stimulates RAS GTPase activity IEA Xenopus tropicalis 58189 R-XTR-8981637 https://reactome.org/PathwayBrowser/#/R-XTR-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Xenopus tropicalis 58189 R-XTR-8982012 https://reactome.org/PathwayBrowser/#/R-XTR-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Xenopus tropicalis 58189 R-XTR-8982018 https://reactome.org/PathwayBrowser/#/R-XTR-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Xenopus tropicalis 58189 R-XTR-8982020 https://reactome.org/PathwayBrowser/#/R-XTR-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Xenopus tropicalis 58189 R-XTR-8982021 https://reactome.org/PathwayBrowser/#/R-XTR-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Xenopus tropicalis 58189 R-XTR-8982025 https://reactome.org/PathwayBrowser/#/R-XTR-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Xenopus tropicalis 58189 R-XTR-8982026 https://reactome.org/PathwayBrowser/#/R-XTR-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Xenopus tropicalis 58189 R-XTR-8985594 https://reactome.org/PathwayBrowser/#/R-XTR-8985594 MYO9B inactivates RHOA IEA Xenopus tropicalis 58189 R-XTR-9012835 https://reactome.org/PathwayBrowser/#/R-XTR-9012835 GDIs block activation of RHOA IEA Xenopus tropicalis 58189 R-XTR-9013022 https://reactome.org/PathwayBrowser/#/R-XTR-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Xenopus tropicalis 58189 R-XTR-9013023 https://reactome.org/PathwayBrowser/#/R-XTR-9013023 RHOB GEFs activate RHOB IEA Xenopus tropicalis 58189 R-XTR-9013143 https://reactome.org/PathwayBrowser/#/R-XTR-9013143 RAC1 GEFs activate RAC1 IEA Xenopus tropicalis 58189 R-XTR-9013144 https://reactome.org/PathwayBrowser/#/R-XTR-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Xenopus tropicalis 58189 R-XTR-9013147 https://reactome.org/PathwayBrowser/#/R-XTR-9013147 RAC1 GDIs block activation of RAC1 IEA Xenopus tropicalis 58189 R-XTR-9013158 https://reactome.org/PathwayBrowser/#/R-XTR-9013158 CDC42 GDIs block activation of CDC42 IEA Xenopus tropicalis 58189 R-XTR-9013159 https://reactome.org/PathwayBrowser/#/R-XTR-9013159 CDC42 GEFs activate CDC42 IEA Xenopus tropicalis 58189 R-XTR-9013161 https://reactome.org/PathwayBrowser/#/R-XTR-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Xenopus tropicalis 58189 R-XTR-9013435 https://reactome.org/PathwayBrowser/#/R-XTR-9013435 RHOD auto-activates IEA Xenopus tropicalis 58189 R-XTR-9013437 https://reactome.org/PathwayBrowser/#/R-XTR-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Xenopus tropicalis 58189 R-XTR-9014293 https://reactome.org/PathwayBrowser/#/R-XTR-9014293 RAC2 GDIs block activation of RAC2 IEA Xenopus tropicalis 58189 R-XTR-9014295 https://reactome.org/PathwayBrowser/#/R-XTR-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Xenopus tropicalis 58189 R-XTR-9014296 https://reactome.org/PathwayBrowser/#/R-XTR-9014296 RAC2 GEFs activate RAC2 IEA Xenopus tropicalis 58189 R-XTR-9014433 https://reactome.org/PathwayBrowser/#/R-XTR-9014433 RHOG GEFs activate RHOG IEA Xenopus tropicalis 58189 R-XTR-9014434 https://reactome.org/PathwayBrowser/#/R-XTR-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Xenopus tropicalis 58189 R-XTR-9014456 https://reactome.org/PathwayBrowser/#/R-XTR-9014456 GDIs block activation of RHOG IEA Xenopus tropicalis 58189 R-XTR-9017488 https://reactome.org/PathwayBrowser/#/R-XTR-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Xenopus tropicalis 58189 R-XTR-9017491 https://reactome.org/PathwayBrowser/#/R-XTR-9017491 RHOJ GEFs activate RHOJ IEA Xenopus tropicalis 58189 R-XTR-9018745 https://reactome.org/PathwayBrowser/#/R-XTR-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Xenopus tropicalis 58189 R-XTR-9018747 https://reactome.org/PathwayBrowser/#/R-XTR-9018747 RHOQ GEFs activate RHOQ IEA Xenopus tropicalis 58189 R-XTR-9018768 https://reactome.org/PathwayBrowser/#/R-XTR-9018768 RHOU auto-activates IEA Xenopus tropicalis 58189 R-XTR-9018798 https://reactome.org/PathwayBrowser/#/R-XTR-9018798 RHOV binds GTP IEA Xenopus tropicalis 58189 R-XTR-9018804 https://reactome.org/PathwayBrowser/#/R-XTR-9018804 RAC3 GEFs activate RAC3 IEA Xenopus tropicalis 58189 R-XTR-9018806 https://reactome.org/PathwayBrowser/#/R-XTR-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Xenopus tropicalis 58189 R-XTR-9018807 https://reactome.org/PathwayBrowser/#/R-XTR-9018807 RAC3 GDIs block activation of RAC3 IEA Xenopus tropicalis 58189 R-XTR-9018826 https://reactome.org/PathwayBrowser/#/R-XTR-9018826 RHOT2 hydrolyzes GTP IEA Xenopus tropicalis 58189 R-XTR-9032798 https://reactome.org/PathwayBrowser/#/R-XTR-9032798 DOCK3 activates RAC1 IEA Xenopus tropicalis 58189 R-XTR-9033949 https://reactome.org/PathwayBrowser/#/R-XTR-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Xenopus tropicalis 58189 R-XTR-9036301 https://reactome.org/PathwayBrowser/#/R-XTR-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Xenopus tropicalis 58189 R-XTR-9036307 https://reactome.org/PathwayBrowser/#/R-XTR-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Xenopus tropicalis 58189 R-XTR-9036987 https://reactome.org/PathwayBrowser/#/R-XTR-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Xenopus tropicalis 58189 R-XTR-927789 https://reactome.org/PathwayBrowser/#/R-XTR-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Xenopus tropicalis 58189 R-XTR-927813 https://reactome.org/PathwayBrowser/#/R-XTR-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Xenopus tropicalis 58189 R-XTR-927832 https://reactome.org/PathwayBrowser/#/R-XTR-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Xenopus tropicalis 58189 R-XTR-927836 https://reactome.org/PathwayBrowser/#/R-XTR-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Xenopus tropicalis 58189 R-XTR-927889 https://reactome.org/PathwayBrowser/#/R-XTR-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Xenopus tropicalis 58189 R-XTR-939265 https://reactome.org/PathwayBrowser/#/R-XTR-939265 Activation of Rap1 by membrane-associated GEFs IEA Xenopus tropicalis 58189 R-XTR-9603982 https://reactome.org/PathwayBrowser/#/R-XTR-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Xenopus tropicalis 58189 R-XTR-9603983 https://reactome.org/PathwayBrowser/#/R-XTR-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Xenopus tropicalis 58189 R-XTR-9603984 https://reactome.org/PathwayBrowser/#/R-XTR-9603984 FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX IEA Xenopus tropicalis 58189 R-XTR-9603986 https://reactome.org/PathwayBrowser/#/R-XTR-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Xenopus tropicalis 58189 R-XTR-9605609 https://reactome.org/PathwayBrowser/#/R-XTR-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Xenopus tropicalis 58189 R-XTR-9605644 https://reactome.org/PathwayBrowser/#/R-XTR-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Xenopus tropicalis 58189 R-XTR-9605682 https://reactome.org/PathwayBrowser/#/R-XTR-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Xenopus tropicalis 58189 R-XTR-9607304 https://reactome.org/PathwayBrowser/#/R-XTR-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Xenopus tropicalis 58189 R-XTR-9624845 https://reactome.org/PathwayBrowser/#/R-XTR-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Xenopus tropicalis 58189 R-XTR-9624893 https://reactome.org/PathwayBrowser/#/R-XTR-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Xenopus tropicalis 58189 R-XTR-9639286 https://reactome.org/PathwayBrowser/#/R-XTR-9639286 RRAGC,D exchanges GTP for GDP IEA Xenopus tropicalis 58189 R-XTR-9640167 https://reactome.org/PathwayBrowser/#/R-XTR-9640167 RRAGA,B exchanges GDP for GTP IEA Xenopus tropicalis 58189 R-XTR-9640168 https://reactome.org/PathwayBrowser/#/R-XTR-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Xenopus tropicalis 58189 R-XTR-9640175 https://reactome.org/PathwayBrowser/#/R-XTR-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Xenopus tropicalis 58189 R-XTR-9640195 https://reactome.org/PathwayBrowser/#/R-XTR-9640195 RRAGA,B hydrolyzes GTP IEA Xenopus tropicalis 58189 R-XTR-9645598 https://reactome.org/PathwayBrowser/#/R-XTR-9645598 RRAGC,D hydrolyzes GTP IEA Xenopus tropicalis 58189 R-XTR-9646468 https://reactome.org/PathwayBrowser/#/R-XTR-9646468 mTORC1 binds RHEB:GTP IEA Xenopus tropicalis 58189 R-XTR-9646679 https://reactome.org/PathwayBrowser/#/R-XTR-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Xenopus tropicalis 58189 R-XTR-9646685 https://reactome.org/PathwayBrowser/#/R-XTR-9646685 Aggresome dissociates from dynein and microtubule IEA Xenopus tropicalis 58189 R-XTR-9648017 https://reactome.org/PathwayBrowser/#/R-XTR-9648017 EML4 binds to microtubules IEA Xenopus tropicalis 58189 R-XTR-9648114 https://reactome.org/PathwayBrowser/#/R-XTR-9648114 EML4 recruits NUDC to mitotic spindle IEA Xenopus tropicalis 58189 R-XTR-9649735 https://reactome.org/PathwayBrowser/#/R-XTR-9649735 Intrinsic nucleotide exchange on RAS IEA Xenopus tropicalis 58189 R-XTR-9649736 https://reactome.org/PathwayBrowser/#/R-XTR-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Xenopus tropicalis 58189 R-XTR-9668419 https://reactome.org/PathwayBrowser/#/R-XTR-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Xenopus tropicalis 58189 R-XTR-9693111 https://reactome.org/PathwayBrowser/#/R-XTR-9693111 RHOF auto-activates IEA Xenopus tropicalis 58189 R-XTR-9693282 https://reactome.org/PathwayBrowser/#/R-XTR-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Xenopus tropicalis 58189 R-XTR-9726862 https://reactome.org/PathwayBrowser/#/R-XTR-9726862 Phosphorylated RHOU translocates to the endosome membrane IEA Xenopus tropicalis 58189 R-XTR-9751201 https://reactome.org/PathwayBrowser/#/R-XTR-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Xenopus tropicalis 58189 R-XTR-983259 https://reactome.org/PathwayBrowser/#/R-XTR-983259 Kinesins move along microtubules consuming ATP IEA Xenopus tropicalis 58189 R-XTR-983266 https://reactome.org/PathwayBrowser/#/R-XTR-983266 Kinesins bind microtubules IEA Xenopus tropicalis 58189 R-XTR-9846332 https://reactome.org/PathwayBrowser/#/R-XTR-9846332 FUT1,2 transfer fucose to gangliosides IEA Xenopus tropicalis 58210 R-BTA-1497784 https://reactome.org/PathwayBrowser/#/R-BTA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Bos taurus 58210 R-BTA-1497796 https://reactome.org/PathwayBrowser/#/R-BTA-1497796 BH2 binding can lead to eNOS uncoupling IEA Bos taurus 58210 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 58210 R-BTA-163217 https://reactome.org/PathwayBrowser/#/R-BTA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Bos taurus 58210 R-BTA-174374 https://reactome.org/PathwayBrowser/#/R-BTA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Bos taurus 58210 R-BTA-196840 https://reactome.org/PathwayBrowser/#/R-BTA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Bos taurus 58210 R-BTA-196929 https://reactome.org/PathwayBrowser/#/R-BTA-196929 FLAD1 phosphorylates FMN IEA Bos taurus 58210 R-BTA-196950 https://reactome.org/PathwayBrowser/#/R-BTA-196950 2xTRAP hydrolyzes FMN to RIB IEA Bos taurus 58210 R-BTA-196955 https://reactome.org/PathwayBrowser/#/R-BTA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Bos taurus 58210 R-BTA-196964 https://reactome.org/PathwayBrowser/#/R-BTA-196964 RFK:Mg2+ phosphorylates RIB IEA Bos taurus 58210 R-BTA-202110 https://reactome.org/PathwayBrowser/#/R-BTA-202110 eNOS:Caveolin-1 complex binds to CaM IEA Bos taurus 58210 R-BTA-202111 https://reactome.org/PathwayBrowser/#/R-BTA-202111 AKT1 phosphorylates eNOS IEA Bos taurus 58210 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 58210 R-BTA-202129 https://reactome.org/PathwayBrowser/#/R-BTA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Bos taurus 58210 R-BTA-202132 https://reactome.org/PathwayBrowser/#/R-BTA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Bos taurus 58210 R-BTA-202144 https://reactome.org/PathwayBrowser/#/R-BTA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Bos taurus 58210 R-BTA-203553 https://reactome.org/PathwayBrowser/#/R-BTA-203553 eNOS binds NOSIP IEA Bos taurus 58210 R-BTA-203565 https://reactome.org/PathwayBrowser/#/R-BTA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Bos taurus 58210 R-BTA-203613 https://reactome.org/PathwayBrowser/#/R-BTA-203613 depalmitoylation of eNOS IEA Bos taurus 58210 R-BTA-203625 https://reactome.org/PathwayBrowser/#/R-BTA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Bos taurus 58210 R-BTA-203680 https://reactome.org/PathwayBrowser/#/R-BTA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Bos taurus 58210 R-BTA-203700 https://reactome.org/PathwayBrowser/#/R-BTA-203700 eNOS translocation from Golgi to Caveolae IEA Bos taurus 58210 R-BTA-203712 https://reactome.org/PathwayBrowser/#/R-BTA-203712 eNOS associates with Caveolin-1 IEA Bos taurus 58210 R-BTA-209921 https://reactome.org/PathwayBrowser/#/R-BTA-209921 Monoiodinated tyrosine can be deiodinated IEA Bos taurus 58210 R-BTA-209960 https://reactome.org/PathwayBrowser/#/R-BTA-209960 Diiodinated tyrosine can be deiodinated IEA Bos taurus 58210 R-BTA-3149518 https://reactome.org/PathwayBrowser/#/R-BTA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Bos taurus 58210 R-BTA-3149539 https://reactome.org/PathwayBrowser/#/R-BTA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Bos taurus 58210 R-BTA-3165230 https://reactome.org/PathwayBrowser/#/R-BTA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Bos taurus 58210 R-BTA-3204318 https://reactome.org/PathwayBrowser/#/R-BTA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Bos taurus 58210 R-BTA-389842 https://reactome.org/PathwayBrowser/#/R-BTA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Bos taurus 58210 R-BTA-389862 https://reactome.org/PathwayBrowser/#/R-BTA-389862 Conversion of glyoxylate to oxalate IEA Bos taurus 58210 R-BTA-6788556 https://reactome.org/PathwayBrowser/#/R-BTA-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Bos taurus 58210 R-BTA-6799179 https://reactome.org/PathwayBrowser/#/R-BTA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Bos taurus 58210 R-BTA-6799196 https://reactome.org/PathwayBrowser/#/R-BTA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Bos taurus 58210 R-BTA-6800870 https://reactome.org/PathwayBrowser/#/R-BTA-6800870 NDUF subunits bind to form the FP subcomplex IEA Bos taurus 58210 R-BTA-73569 https://reactome.org/PathwayBrowser/#/R-BTA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Bos taurus 58210 R-BTA-73585 https://reactome.org/PathwayBrowser/#/R-BTA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Bos taurus 58210 R-BTA-73616 https://reactome.org/PathwayBrowser/#/R-BTA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Bos taurus 58210 R-BTA-965019 https://reactome.org/PathwayBrowser/#/R-BTA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Bos taurus 58210 R-BTA-965079 https://reactome.org/PathwayBrowser/#/R-BTA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Bos taurus 58210 R-BTA-9708759 https://reactome.org/PathwayBrowser/#/R-BTA-9708759 DHODH:FMN binds DHODH inhibitors IEA Bos taurus 58210 R-CEL-1497784 https://reactome.org/PathwayBrowser/#/R-CEL-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Caenorhabditis elegans 58210 R-CEL-1497796 https://reactome.org/PathwayBrowser/#/R-CEL-1497796 BH2 binding can lead to eNOS uncoupling IEA Caenorhabditis elegans 58210 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 58210 R-CEL-174374 https://reactome.org/PathwayBrowser/#/R-CEL-174374 MTR transfers CH3 from MeCbl to HCYS IEA Caenorhabditis elegans 58210 R-CEL-196840 https://reactome.org/PathwayBrowser/#/R-CEL-196840 3xPPCDC:3FMN decarboxylates PPC IEA Caenorhabditis elegans 58210 R-CEL-196929 https://reactome.org/PathwayBrowser/#/R-CEL-196929 FLAD1 phosphorylates FMN IEA Caenorhabditis elegans 58210 R-CEL-196950 https://reactome.org/PathwayBrowser/#/R-CEL-196950 2xTRAP hydrolyzes FMN to RIB IEA Caenorhabditis elegans 58210 R-CEL-196955 https://reactome.org/PathwayBrowser/#/R-CEL-196955 2xENPP1 hydrolyzes FAD to FMN IEA Caenorhabditis elegans 58210 R-CEL-196964 https://reactome.org/PathwayBrowser/#/R-CEL-196964 RFK:Mg2+ phosphorylates RIB IEA Caenorhabditis elegans 58210 R-CEL-202111 https://reactome.org/PathwayBrowser/#/R-CEL-202111 AKT1 phosphorylates eNOS IEA Caenorhabditis elegans 58210 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 58210 R-CEL-209921 https://reactome.org/PathwayBrowser/#/R-CEL-209921 Monoiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 58210 R-CEL-209960 https://reactome.org/PathwayBrowser/#/R-CEL-209960 Diiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 58210 R-CEL-3149518 https://reactome.org/PathwayBrowser/#/R-CEL-3149518 MTRR reduces cob(II)alamin to meCbl IEA Caenorhabditis elegans 58210 R-CEL-3149539 https://reactome.org/PathwayBrowser/#/R-CEL-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Caenorhabditis elegans 58210 R-CEL-3165230 https://reactome.org/PathwayBrowser/#/R-CEL-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Caenorhabditis elegans 58210 R-CEL-3204318 https://reactome.org/PathwayBrowser/#/R-CEL-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Caenorhabditis elegans 58210 R-CEL-389842 https://reactome.org/PathwayBrowser/#/R-CEL-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Caenorhabditis elegans 58210 R-CEL-389862 https://reactome.org/PathwayBrowser/#/R-CEL-389862 Conversion of glyoxylate to oxalate IEA Caenorhabditis elegans 58210 R-CEL-73569 https://reactome.org/PathwayBrowser/#/R-CEL-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Caenorhabditis elegans 58210 R-CEL-73585 https://reactome.org/PathwayBrowser/#/R-CEL-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Caenorhabditis elegans 58210 R-CEL-73616 https://reactome.org/PathwayBrowser/#/R-CEL-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Caenorhabditis elegans 58210 R-CEL-965019 https://reactome.org/PathwayBrowser/#/R-CEL-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Caenorhabditis elegans 58210 R-CEL-965079 https://reactome.org/PathwayBrowser/#/R-CEL-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Caenorhabditis elegans 58210 R-CEL-9708759 https://reactome.org/PathwayBrowser/#/R-CEL-9708759 DHODH:FMN binds DHODH inhibitors IEA Caenorhabditis elegans 58210 R-CFA-163217 https://reactome.org/PathwayBrowser/#/R-CFA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Canis familiaris 58210 R-CFA-174374 https://reactome.org/PathwayBrowser/#/R-CFA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Canis familiaris 58210 R-CFA-196840 https://reactome.org/PathwayBrowser/#/R-CFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Canis familiaris 58210 R-CFA-196929 https://reactome.org/PathwayBrowser/#/R-CFA-196929 FLAD1 phosphorylates FMN IEA Canis familiaris 58210 R-CFA-196950 https://reactome.org/PathwayBrowser/#/R-CFA-196950 2xTRAP hydrolyzes FMN to RIB IEA Canis familiaris 58210 R-CFA-196955 https://reactome.org/PathwayBrowser/#/R-CFA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Canis familiaris 58210 R-CFA-196964 https://reactome.org/PathwayBrowser/#/R-CFA-196964 RFK:Mg2+ phosphorylates RIB IEA Canis familiaris 58210 R-CFA-203565 https://reactome.org/PathwayBrowser/#/R-CFA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Canis familiaris 58210 R-CFA-203625 https://reactome.org/PathwayBrowser/#/R-CFA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Canis familiaris 58210 R-CFA-209921 https://reactome.org/PathwayBrowser/#/R-CFA-209921 Monoiodinated tyrosine can be deiodinated IEA Canis familiaris 58210 R-CFA-209960 https://reactome.org/PathwayBrowser/#/R-CFA-209960 Diiodinated tyrosine can be deiodinated IEA Canis familiaris 58210 R-CFA-3149518 https://reactome.org/PathwayBrowser/#/R-CFA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Canis familiaris 58210 R-CFA-3149539 https://reactome.org/PathwayBrowser/#/R-CFA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Canis familiaris 58210 R-CFA-3165230 https://reactome.org/PathwayBrowser/#/R-CFA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Canis familiaris 58210 R-CFA-3204318 https://reactome.org/PathwayBrowser/#/R-CFA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Canis familiaris 58210 R-CFA-389842 https://reactome.org/PathwayBrowser/#/R-CFA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Canis familiaris 58210 R-CFA-389862 https://reactome.org/PathwayBrowser/#/R-CFA-389862 Conversion of glyoxylate to oxalate IEA Canis familiaris 58210 R-CFA-6788556 https://reactome.org/PathwayBrowser/#/R-CFA-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Canis familiaris 58210 R-CFA-6799179 https://reactome.org/PathwayBrowser/#/R-CFA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Canis familiaris 58210 R-CFA-6799196 https://reactome.org/PathwayBrowser/#/R-CFA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Canis familiaris 58210 R-CFA-73569 https://reactome.org/PathwayBrowser/#/R-CFA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Canis familiaris 58210 R-CFA-73585 https://reactome.org/PathwayBrowser/#/R-CFA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Canis familiaris 58210 R-CFA-73616 https://reactome.org/PathwayBrowser/#/R-CFA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Canis familiaris 58210 R-CFA-965019 https://reactome.org/PathwayBrowser/#/R-CFA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Canis familiaris 58210 R-CFA-965079 https://reactome.org/PathwayBrowser/#/R-CFA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Canis familiaris 58210 R-CFA-9708759 https://reactome.org/PathwayBrowser/#/R-CFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Canis familiaris 58210 R-DDI-1497784 https://reactome.org/PathwayBrowser/#/R-DDI-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Dictyostelium discoideum 58210 R-DDI-1497796 https://reactome.org/PathwayBrowser/#/R-DDI-1497796 BH2 binding can lead to eNOS uncoupling IEA Dictyostelium discoideum 58210 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 58210 R-DDI-174374 https://reactome.org/PathwayBrowser/#/R-DDI-174374 MTR transfers CH3 from MeCbl to HCYS IEA Dictyostelium discoideum 58210 R-DDI-196840 https://reactome.org/PathwayBrowser/#/R-DDI-196840 3xPPCDC:3FMN decarboxylates PPC IEA Dictyostelium discoideum 58210 R-DDI-196929 https://reactome.org/PathwayBrowser/#/R-DDI-196929 FLAD1 phosphorylates FMN IEA Dictyostelium discoideum 58210 R-DDI-196955 https://reactome.org/PathwayBrowser/#/R-DDI-196955 2xENPP1 hydrolyzes FAD to FMN IEA Dictyostelium discoideum 58210 R-DDI-202111 https://reactome.org/PathwayBrowser/#/R-DDI-202111 AKT1 phosphorylates eNOS IEA Dictyostelium discoideum 58210 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 58210 R-DDI-202132 https://reactome.org/PathwayBrowser/#/R-DDI-202132 depalmitoylated eNOS translocates from plasma membrane IEA Dictyostelium discoideum 58210 R-DDI-202137 https://reactome.org/PathwayBrowser/#/R-DDI-202137 AKT1 binds eNOS complex via HSP90 IEA Dictyostelium discoideum 58210 R-DDI-203553 https://reactome.org/PathwayBrowser/#/R-DDI-203553 eNOS binds NOSIP IEA Dictyostelium discoideum 58210 R-DDI-203613 https://reactome.org/PathwayBrowser/#/R-DDI-203613 depalmitoylation of eNOS IEA Dictyostelium discoideum 58210 R-DDI-203680 https://reactome.org/PathwayBrowser/#/R-DDI-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Dictyostelium discoideum 58210 R-DDI-203700 https://reactome.org/PathwayBrowser/#/R-DDI-203700 eNOS translocation from Golgi to Caveolae IEA Dictyostelium discoideum 58210 R-DDI-3149518 https://reactome.org/PathwayBrowser/#/R-DDI-3149518 MTRR reduces cob(II)alamin to meCbl IEA Dictyostelium discoideum 58210 R-DDI-3149539 https://reactome.org/PathwayBrowser/#/R-DDI-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Dictyostelium discoideum 58210 R-DDI-389842 https://reactome.org/PathwayBrowser/#/R-DDI-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Dictyostelium discoideum 58210 R-DDI-389862 https://reactome.org/PathwayBrowser/#/R-DDI-389862 Conversion of glyoxylate to oxalate IEA Dictyostelium discoideum 58210 R-DDI-6788556 https://reactome.org/PathwayBrowser/#/R-DDI-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Dictyostelium discoideum 58210 R-DDI-73585 https://reactome.org/PathwayBrowser/#/R-DDI-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Dictyostelium discoideum 58210 R-DDI-73616 https://reactome.org/PathwayBrowser/#/R-DDI-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Dictyostelium discoideum 58210 R-DDI-965019 https://reactome.org/PathwayBrowser/#/R-DDI-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Dictyostelium discoideum 58210 R-DDI-965079 https://reactome.org/PathwayBrowser/#/R-DDI-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Dictyostelium discoideum 58210 R-DME-1497784 https://reactome.org/PathwayBrowser/#/R-DME-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Drosophila melanogaster 58210 R-DME-1497796 https://reactome.org/PathwayBrowser/#/R-DME-1497796 BH2 binding can lead to eNOS uncoupling IEA Drosophila melanogaster 58210 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 58210 R-DME-163217 https://reactome.org/PathwayBrowser/#/R-DME-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Drosophila melanogaster 58210 R-DME-196840 https://reactome.org/PathwayBrowser/#/R-DME-196840 3xPPCDC:3FMN decarboxylates PPC IEA Drosophila melanogaster 58210 R-DME-196929 https://reactome.org/PathwayBrowser/#/R-DME-196929 FLAD1 phosphorylates FMN IEA Drosophila melanogaster 58210 R-DME-196964 https://reactome.org/PathwayBrowser/#/R-DME-196964 RFK:Mg2+ phosphorylates RIB IEA Drosophila melanogaster 58210 R-DME-202111 https://reactome.org/PathwayBrowser/#/R-DME-202111 AKT1 phosphorylates eNOS IEA Drosophila melanogaster 58210 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 58210 R-DME-202132 https://reactome.org/PathwayBrowser/#/R-DME-202132 depalmitoylated eNOS translocates from plasma membrane IEA Drosophila melanogaster 58210 R-DME-202137 https://reactome.org/PathwayBrowser/#/R-DME-202137 AKT1 binds eNOS complex via HSP90 IEA Drosophila melanogaster 58210 R-DME-203553 https://reactome.org/PathwayBrowser/#/R-DME-203553 eNOS binds NOSIP IEA Drosophila melanogaster 58210 R-DME-203613 https://reactome.org/PathwayBrowser/#/R-DME-203613 depalmitoylation of eNOS IEA Drosophila melanogaster 58210 R-DME-203680 https://reactome.org/PathwayBrowser/#/R-DME-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Drosophila melanogaster 58210 R-DME-203700 https://reactome.org/PathwayBrowser/#/R-DME-203700 eNOS translocation from Golgi to Caveolae IEA Drosophila melanogaster 58210 R-DME-209921 https://reactome.org/PathwayBrowser/#/R-DME-209921 Monoiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 58210 R-DME-209960 https://reactome.org/PathwayBrowser/#/R-DME-209960 Diiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 58210 R-DME-3165230 https://reactome.org/PathwayBrowser/#/R-DME-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Drosophila melanogaster 58210 R-DME-389842 https://reactome.org/PathwayBrowser/#/R-DME-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Drosophila melanogaster 58210 R-DME-389862 https://reactome.org/PathwayBrowser/#/R-DME-389862 Conversion of glyoxylate to oxalate IEA Drosophila melanogaster 58210 R-DME-6788556 https://reactome.org/PathwayBrowser/#/R-DME-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Drosophila melanogaster 58210 R-DME-6799196 https://reactome.org/PathwayBrowser/#/R-DME-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Drosophila melanogaster 58210 R-DME-73569 https://reactome.org/PathwayBrowser/#/R-DME-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Drosophila melanogaster 58210 R-DME-73585 https://reactome.org/PathwayBrowser/#/R-DME-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Drosophila melanogaster 58210 R-DME-73616 https://reactome.org/PathwayBrowser/#/R-DME-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Drosophila melanogaster 58210 R-DME-965019 https://reactome.org/PathwayBrowser/#/R-DME-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Drosophila melanogaster 58210 R-DME-965079 https://reactome.org/PathwayBrowser/#/R-DME-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Drosophila melanogaster 58210 R-DME-9708759 https://reactome.org/PathwayBrowser/#/R-DME-9708759 DHODH:FMN binds DHODH inhibitors IEA Drosophila melanogaster 58210 R-DRE-163217 https://reactome.org/PathwayBrowser/#/R-DRE-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Danio rerio 58210 R-DRE-196929 https://reactome.org/PathwayBrowser/#/R-DRE-196929 FLAD1 phosphorylates FMN IEA Danio rerio 58210 R-DRE-196950 https://reactome.org/PathwayBrowser/#/R-DRE-196950 2xTRAP hydrolyzes FMN to RIB IEA Danio rerio 58210 R-DRE-196955 https://reactome.org/PathwayBrowser/#/R-DRE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Danio rerio 58210 R-DRE-203565 https://reactome.org/PathwayBrowser/#/R-DRE-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Danio rerio 58210 R-DRE-203625 https://reactome.org/PathwayBrowser/#/R-DRE-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Danio rerio 58210 R-DRE-209921 https://reactome.org/PathwayBrowser/#/R-DRE-209921 Monoiodinated tyrosine can be deiodinated IEA Danio rerio 58210 R-DRE-209960 https://reactome.org/PathwayBrowser/#/R-DRE-209960 Diiodinated tyrosine can be deiodinated IEA Danio rerio 58210 R-DRE-3165230 https://reactome.org/PathwayBrowser/#/R-DRE-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Danio rerio 58210 R-DRE-389842 https://reactome.org/PathwayBrowser/#/R-DRE-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Danio rerio 58210 R-DRE-389862 https://reactome.org/PathwayBrowser/#/R-DRE-389862 Conversion of glyoxylate to oxalate IEA Danio rerio 58210 R-DRE-6788556 https://reactome.org/PathwayBrowser/#/R-DRE-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Danio rerio 58210 R-DRE-73569 https://reactome.org/PathwayBrowser/#/R-DRE-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Danio rerio 58210 R-DRE-73585 https://reactome.org/PathwayBrowser/#/R-DRE-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Danio rerio 58210 R-DRE-73616 https://reactome.org/PathwayBrowser/#/R-DRE-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Danio rerio 58210 R-DRE-9708759 https://reactome.org/PathwayBrowser/#/R-DRE-9708759 DHODH:FMN binds DHODH inhibitors IEA Danio rerio 58210 R-GGA-1497784 https://reactome.org/PathwayBrowser/#/R-GGA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Gallus gallus 58210 R-GGA-1497796 https://reactome.org/PathwayBrowser/#/R-GGA-1497796 BH2 binding can lead to eNOS uncoupling IEA Gallus gallus 58210 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 58210 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Gallus gallus 58210 R-GGA-174374 https://reactome.org/PathwayBrowser/#/R-GGA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Gallus gallus 58210 R-GGA-196840 https://reactome.org/PathwayBrowser/#/R-GGA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Gallus gallus 58210 R-GGA-196929 https://reactome.org/PathwayBrowser/#/R-GGA-196929 FLAD1 phosphorylates FMN IEA Gallus gallus 58210 R-GGA-196950 https://reactome.org/PathwayBrowser/#/R-GGA-196950 2xTRAP hydrolyzes FMN to RIB IEA Gallus gallus 58210 R-GGA-196964 https://reactome.org/PathwayBrowser/#/R-GGA-196964 RFK:Mg2+ phosphorylates RIB IEA Gallus gallus 58210 R-GGA-202110 https://reactome.org/PathwayBrowser/#/R-GGA-202110 eNOS:Caveolin-1 complex binds to CaM IEA Gallus gallus 58210 R-GGA-202111 https://reactome.org/PathwayBrowser/#/R-GGA-202111 AKT1 phosphorylates eNOS IEA Gallus gallus 58210 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 58210 R-GGA-202129 https://reactome.org/PathwayBrowser/#/R-GGA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Gallus gallus 58210 R-GGA-202132 https://reactome.org/PathwayBrowser/#/R-GGA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Gallus gallus 58210 R-GGA-202137 https://reactome.org/PathwayBrowser/#/R-GGA-202137 AKT1 binds eNOS complex via HSP90 IEA Gallus gallus 58210 R-GGA-202144 https://reactome.org/PathwayBrowser/#/R-GGA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Gallus gallus 58210 R-GGA-203565 https://reactome.org/PathwayBrowser/#/R-GGA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Gallus gallus 58210 R-GGA-203613 https://reactome.org/PathwayBrowser/#/R-GGA-203613 depalmitoylation of eNOS IEA Gallus gallus 58210 R-GGA-203625 https://reactome.org/PathwayBrowser/#/R-GGA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Gallus gallus 58210 R-GGA-203700 https://reactome.org/PathwayBrowser/#/R-GGA-203700 eNOS translocation from Golgi to Caveolae IEA Gallus gallus 58210 R-GGA-203712 https://reactome.org/PathwayBrowser/#/R-GGA-203712 eNOS associates with Caveolin-1 IEA Gallus gallus 58210 R-GGA-209921 https://reactome.org/PathwayBrowser/#/R-GGA-209921 Monoiodinated tyrosine can be deiodinated IEA Gallus gallus 58210 R-GGA-209960 https://reactome.org/PathwayBrowser/#/R-GGA-209960 Diiodinated tyrosine can be deiodinated IEA Gallus gallus 58210 R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus 58210 R-GGA-3149539 https://reactome.org/PathwayBrowser/#/R-GGA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Gallus gallus 58210 R-GGA-3165230 https://reactome.org/PathwayBrowser/#/R-GGA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Gallus gallus 58210 R-GGA-3204318 https://reactome.org/PathwayBrowser/#/R-GGA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Gallus gallus 58210 R-GGA-389842 https://reactome.org/PathwayBrowser/#/R-GGA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Gallus gallus 58210 R-GGA-389862 https://reactome.org/PathwayBrowser/#/R-GGA-389862 Conversion of glyoxylate to oxalate IEA Gallus gallus 58210 R-GGA-419452 https://reactome.org/PathwayBrowser/#/R-GGA-419452 (S)-dihydroorotate + ubiquinone => orotate + ubiquinol IEA Gallus gallus 58210 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus 58210 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus 58210 R-GGA-73569 https://reactome.org/PathwayBrowser/#/R-GGA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Gallus gallus 58210 R-GGA-73585 https://reactome.org/PathwayBrowser/#/R-GGA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Gallus gallus 58210 R-GGA-73616 https://reactome.org/PathwayBrowser/#/R-GGA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Gallus gallus 58210 R-GGA-965019 https://reactome.org/PathwayBrowser/#/R-GGA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Gallus gallus 58210 R-GGA-965079 https://reactome.org/PathwayBrowser/#/R-GGA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Gallus gallus 58210 R-GGA-9708759 https://reactome.org/PathwayBrowser/#/R-GGA-9708759 DHODH:FMN binds DHODH inhibitors IEA Gallus gallus 58210 R-HSA-1497784 https://reactome.org/PathwayBrowser/#/R-HSA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle TAS Homo sapiens 58210 R-HSA-1497796 https://reactome.org/PathwayBrowser/#/R-HSA-1497796 BH2 binding can lead to eNOS uncoupling TAS Homo sapiens 58210 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 58210 R-HSA-163217 https://reactome.org/PathwayBrowser/#/R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 TAS Homo sapiens 58210 R-HSA-174374 https://reactome.org/PathwayBrowser/#/R-HSA-174374 MTR transfers CH3 from MeCbl to HCYS TAS Homo sapiens 58210 R-HSA-196840 https://reactome.org/PathwayBrowser/#/R-HSA-196840 3xPPCDC:3FMN decarboxylates PPC TAS Homo sapiens 58210 R-HSA-196929 https://reactome.org/PathwayBrowser/#/R-HSA-196929 FLAD1 phosphorylates FMN TAS Homo sapiens 58210 R-HSA-196950 https://reactome.org/PathwayBrowser/#/R-HSA-196950 2xTRAP hydrolyzes FMN to RIB TAS Homo sapiens 58210 R-HSA-196955 https://reactome.org/PathwayBrowser/#/R-HSA-196955 2xENPP1 hydrolyzes FAD to FMN TAS Homo sapiens 58210 R-HSA-196964 https://reactome.org/PathwayBrowser/#/R-HSA-196964 RFK:Mg2+ phosphorylates RIB TAS Homo sapiens 58210 R-HSA-202110 https://reactome.org/PathwayBrowser/#/R-HSA-202110 eNOS:Caveolin-1 complex binds to CaM TAS Homo sapiens 58210 R-HSA-202111 https://reactome.org/PathwayBrowser/#/R-HSA-202111 AKT1 phosphorylates eNOS TAS Homo sapiens 58210 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 58210 R-HSA-202129 https://reactome.org/PathwayBrowser/#/R-HSA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex TAS Homo sapiens 58210 R-HSA-202132 https://reactome.org/PathwayBrowser/#/R-HSA-202132 depalmitoylated eNOS translocates from plasma membrane TAS Homo sapiens 58210 R-HSA-202137 https://reactome.org/PathwayBrowser/#/R-HSA-202137 AKT1 binds eNOS complex via HSP90 TAS Homo sapiens 58210 R-HSA-202144 https://reactome.org/PathwayBrowser/#/R-HSA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex TAS Homo sapiens 58210 R-HSA-203553 https://reactome.org/PathwayBrowser/#/R-HSA-203553 eNOS binds NOSIP TAS Homo sapiens 58210 R-HSA-203565 https://reactome.org/PathwayBrowser/#/R-HSA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP TAS Homo sapiens 58210 R-HSA-203613 https://reactome.org/PathwayBrowser/#/R-HSA-203613 depalmitoylation of eNOS TAS Homo sapiens 58210 R-HSA-203625 https://reactome.org/PathwayBrowser/#/R-HSA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane TAS Homo sapiens 58210 R-HSA-203662 https://reactome.org/PathwayBrowser/#/R-HSA-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 TAS Homo sapiens 58210 R-HSA-203680 https://reactome.org/PathwayBrowser/#/R-HSA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments TAS Homo sapiens 58210 R-HSA-203700 https://reactome.org/PathwayBrowser/#/R-HSA-203700 eNOS translocation from Golgi to Caveolae TAS Homo sapiens 58210 R-HSA-203712 https://reactome.org/PathwayBrowser/#/R-HSA-203712 eNOS associates with Caveolin-1 TAS Homo sapiens 58210 R-HSA-203716 https://reactome.org/PathwayBrowser/#/R-HSA-203716 eNOS:Caveolin-1 complex binds to Nostrin TAS Homo sapiens 58210 R-HSA-209921 https://reactome.org/PathwayBrowser/#/R-HSA-209921 Monoiodinated tyrosine can be deiodinated TAS Homo sapiens 58210 R-HSA-209960 https://reactome.org/PathwayBrowser/#/R-HSA-209960 Diiodinated tyrosine can be deiodinated TAS Homo sapiens 58210 R-HSA-2564824 https://reactome.org/PathwayBrowser/#/R-HSA-2564824 NADPH reduces NDOR1:CIAPIN1 IEA Homo sapiens 58210 R-HSA-2564826 https://reactome.org/PathwayBrowser/#/R-HSA-2564826 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold IEA Homo sapiens 58210 R-HSA-3149518 https://reactome.org/PathwayBrowser/#/R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl TAS Homo sapiens 58210 R-HSA-3149539 https://reactome.org/PathwayBrowser/#/R-HSA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin TAS Homo sapiens 58210 R-HSA-3165230 https://reactome.org/PathwayBrowser/#/R-HSA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol TAS Homo sapiens 58210 R-HSA-3204318 https://reactome.org/PathwayBrowser/#/R-HSA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR TAS Homo sapiens 58210 R-HSA-3318563 https://reactome.org/PathwayBrowser/#/R-HSA-3318563 Defective MTRR does not convert cob(II)alamin to MeCbl TAS Homo sapiens 58210 R-HSA-3321918 https://reactome.org/PathwayBrowser/#/R-HSA-3321918 Defective MTR does not transfer CH3 group from MTHF to cob(I)alamin TAS Homo sapiens 58210 R-HSA-3322140 https://reactome.org/PathwayBrowser/#/R-HSA-3322140 Defective MTR does not transfer CH3 group from MeCbl to HCYS TAS Homo sapiens 58210 R-HSA-389842 https://reactome.org/PathwayBrowser/#/R-HSA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate TAS Homo sapiens 58210 R-HSA-389862 https://reactome.org/PathwayBrowser/#/R-HSA-389862 Conversion of glyoxylate to oxalate TAS Homo sapiens 58210 R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 58210 R-HSA-6788556 https://reactome.org/PathwayBrowser/#/R-HSA-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 TAS Homo sapiens 58210 R-HSA-6799179 https://reactome.org/PathwayBrowser/#/R-HSA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex TAS Homo sapiens 58210 R-HSA-6799196 https://reactome.org/PathwayBrowser/#/R-HSA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I TAS Homo sapiens 58210 R-HSA-6800870 https://reactome.org/PathwayBrowser/#/R-HSA-6800870 NDUF subunits bind to form the FP subcomplex TAS Homo sapiens 58210 R-HSA-73569 https://reactome.org/PathwayBrowser/#/R-HSA-73569 DHODH:FMN oxidises (S)-DHO to orotate TAS Homo sapiens 58210 R-HSA-73585 https://reactome.org/PathwayBrowser/#/R-HSA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ TAS Homo sapiens 58210 R-HSA-73616 https://reactome.org/PathwayBrowser/#/R-HSA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ TAS Homo sapiens 58210 R-HSA-965019 https://reactome.org/PathwayBrowser/#/R-HSA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP TAS Homo sapiens 58210 R-HSA-965079 https://reactome.org/PathwayBrowser/#/R-HSA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP TAS Homo sapiens 58210 R-HSA-9708759 https://reactome.org/PathwayBrowser/#/R-HSA-9708759 DHODH:FMN binds DHODH inhibitors TAS Homo sapiens 58210 R-MMU-1497784 https://reactome.org/PathwayBrowser/#/R-MMU-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Mus musculus 58210 R-MMU-1497796 https://reactome.org/PathwayBrowser/#/R-MMU-1497796 BH2 binding can lead to eNOS uncoupling IEA Mus musculus 58210 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 58210 R-MMU-163217 https://reactome.org/PathwayBrowser/#/R-MMU-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Mus musculus 58210 R-MMU-174374 https://reactome.org/PathwayBrowser/#/R-MMU-174374 MTR transfers CH3 from MeCbl to HCYS IEA Mus musculus 58210 R-MMU-196840 https://reactome.org/PathwayBrowser/#/R-MMU-196840 3xPPCDC:3FMN decarboxylates PPC IEA Mus musculus 58210 R-MMU-196929 https://reactome.org/PathwayBrowser/#/R-MMU-196929 FLAD1 phosphorylates FMN IEA Mus musculus 58210 R-MMU-196950 https://reactome.org/PathwayBrowser/#/R-MMU-196950 2xTRAP hydrolyzes FMN to RIB IEA Mus musculus 58210 R-MMU-196955 https://reactome.org/PathwayBrowser/#/R-MMU-196955 2xENPP1 hydrolyzes FAD to FMN IEA Mus musculus 58210 R-MMU-196964 https://reactome.org/PathwayBrowser/#/R-MMU-196964 RFK:Mg2+ phosphorylates RIB IEA Mus musculus 58210 R-MMU-202110 https://reactome.org/PathwayBrowser/#/R-MMU-202110 eNOS:Caveolin-1 complex binds to CaM IEA Mus musculus 58210 R-MMU-202111 https://reactome.org/PathwayBrowser/#/R-MMU-202111 AKT1 phosphorylates eNOS IEA Mus musculus 58210 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 58210 R-MMU-202129 https://reactome.org/PathwayBrowser/#/R-MMU-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Mus musculus 58210 R-MMU-202132 https://reactome.org/PathwayBrowser/#/R-MMU-202132 depalmitoylated eNOS translocates from plasma membrane IEA Mus musculus 58210 R-MMU-202137 https://reactome.org/PathwayBrowser/#/R-MMU-202137 AKT1 binds eNOS complex via HSP90 IEA Mus musculus 58210 R-MMU-202144 https://reactome.org/PathwayBrowser/#/R-MMU-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Mus musculus 58210 R-MMU-203553 https://reactome.org/PathwayBrowser/#/R-MMU-203553 eNOS binds NOSIP IEA Mus musculus 58210 R-MMU-203613 https://reactome.org/PathwayBrowser/#/R-MMU-203613 depalmitoylation of eNOS IEA Mus musculus 58210 R-MMU-203625 https://reactome.org/PathwayBrowser/#/R-MMU-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Mus musculus 58210 R-MMU-203662 https://reactome.org/PathwayBrowser/#/R-MMU-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Mus musculus 58210 R-MMU-203680 https://reactome.org/PathwayBrowser/#/R-MMU-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Mus musculus 58210 R-MMU-203700 https://reactome.org/PathwayBrowser/#/R-MMU-203700 eNOS translocation from Golgi to Caveolae IEA Mus musculus 58210 R-MMU-203712 https://reactome.org/PathwayBrowser/#/R-MMU-203712 eNOS associates with Caveolin-1 IEA Mus musculus 58210 R-MMU-203716 https://reactome.org/PathwayBrowser/#/R-MMU-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Mus musculus 58210 R-MMU-209921 https://reactome.org/PathwayBrowser/#/R-MMU-209921 Monoiodinated tyrosine can be deiodinated IEA Mus musculus 58210 R-MMU-209960 https://reactome.org/PathwayBrowser/#/R-MMU-209960 Diiodinated tyrosine can be deiodinated IEA Mus musculus 58210 R-MMU-3149518 https://reactome.org/PathwayBrowser/#/R-MMU-3149518 MTRR reduces cob(II)alamin to meCbl IEA Mus musculus 58210 R-MMU-3149539 https://reactome.org/PathwayBrowser/#/R-MMU-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Mus musculus 58210 R-MMU-3165230 https://reactome.org/PathwayBrowser/#/R-MMU-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Mus musculus 58210 R-MMU-3204318 https://reactome.org/PathwayBrowser/#/R-MMU-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Mus musculus 58210 R-MMU-389842 https://reactome.org/PathwayBrowser/#/R-MMU-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Mus musculus 58210 R-MMU-389862 https://reactome.org/PathwayBrowser/#/R-MMU-389862 Conversion of glyoxylate to oxalate IEA Mus musculus 58210 R-MMU-6788556 https://reactome.org/PathwayBrowser/#/R-MMU-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Mus musculus 58210 R-MMU-6799179 https://reactome.org/PathwayBrowser/#/R-MMU-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Mus musculus 58210 R-MMU-6799196 https://reactome.org/PathwayBrowser/#/R-MMU-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Mus musculus 58210 R-MMU-6800870 https://reactome.org/PathwayBrowser/#/R-MMU-6800870 NDUF subunits bind to form the FP subcomplex IEA Mus musculus 58210 R-MMU-73569 https://reactome.org/PathwayBrowser/#/R-MMU-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Mus musculus 58210 R-MMU-73585 https://reactome.org/PathwayBrowser/#/R-MMU-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Mus musculus 58210 R-MMU-73616 https://reactome.org/PathwayBrowser/#/R-MMU-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Mus musculus 58210 R-MMU-965019 https://reactome.org/PathwayBrowser/#/R-MMU-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Mus musculus 58210 R-MMU-965079 https://reactome.org/PathwayBrowser/#/R-MMU-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Mus musculus 58210 R-MMU-9708759 https://reactome.org/PathwayBrowser/#/R-MMU-9708759 DHODH:FMN binds DHODH inhibitors IEA Mus musculus 58210 R-MTU-964884 https://reactome.org/PathwayBrowser/#/R-MTU-964884 Dephosphorylation of EPSP yields chorismate TAS Mycobacterium tuberculosis 58210 R-PFA-1497784 https://reactome.org/PathwayBrowser/#/R-PFA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Plasmodium falciparum 58210 R-PFA-1497796 https://reactome.org/PathwayBrowser/#/R-PFA-1497796 BH2 binding can lead to eNOS uncoupling IEA Plasmodium falciparum 58210 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 58210 R-PFA-196840 https://reactome.org/PathwayBrowser/#/R-PFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Plasmodium falciparum 58210 R-PFA-196929 https://reactome.org/PathwayBrowser/#/R-PFA-196929 FLAD1 phosphorylates FMN IEA Plasmodium falciparum 58210 R-PFA-196950 https://reactome.org/PathwayBrowser/#/R-PFA-196950 2xTRAP hydrolyzes FMN to RIB IEA Plasmodium falciparum 58210 R-PFA-196964 https://reactome.org/PathwayBrowser/#/R-PFA-196964 RFK:Mg2+ phosphorylates RIB IEA Plasmodium falciparum 58210 R-PFA-202111 https://reactome.org/PathwayBrowser/#/R-PFA-202111 AKT1 phosphorylates eNOS IEA Plasmodium falciparum 58210 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 58210 R-PFA-202132 https://reactome.org/PathwayBrowser/#/R-PFA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Plasmodium falciparum 58210 R-PFA-203553 https://reactome.org/PathwayBrowser/#/R-PFA-203553 eNOS binds NOSIP IEA Plasmodium falciparum 58210 R-PFA-203680 https://reactome.org/PathwayBrowser/#/R-PFA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Plasmodium falciparum 58210 R-PFA-203700 https://reactome.org/PathwayBrowser/#/R-PFA-203700 eNOS translocation from Golgi to Caveolae IEA Plasmodium falciparum 58210 R-PFA-73569 https://reactome.org/PathwayBrowser/#/R-PFA-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Plasmodium falciparum 58210 R-PFA-9708759 https://reactome.org/PathwayBrowser/#/R-PFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Plasmodium falciparum 58210 R-RNO-1497784 https://reactome.org/PathwayBrowser/#/R-RNO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Rattus norvegicus 58210 R-RNO-1497796 https://reactome.org/PathwayBrowser/#/R-RNO-1497796 BH2 binding can lead to eNOS uncoupling IEA Rattus norvegicus 58210 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 58210 R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Rattus norvegicus 58210 R-RNO-174374 https://reactome.org/PathwayBrowser/#/R-RNO-174374 MTR transfers CH3 from MeCbl to HCYS IEA Rattus norvegicus 58210 R-RNO-196840 https://reactome.org/PathwayBrowser/#/R-RNO-196840 3xPPCDC:3FMN decarboxylates PPC IEA Rattus norvegicus 58210 R-RNO-196929 https://reactome.org/PathwayBrowser/#/R-RNO-196929 FLAD1 phosphorylates FMN IEA Rattus norvegicus 58210 R-RNO-196950 https://reactome.org/PathwayBrowser/#/R-RNO-196950 2xTRAP hydrolyzes FMN to RIB IEA Rattus norvegicus 58210 R-RNO-196955 https://reactome.org/PathwayBrowser/#/R-RNO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Rattus norvegicus 58210 R-RNO-196964 https://reactome.org/PathwayBrowser/#/R-RNO-196964 RFK:Mg2+ phosphorylates RIB IEA Rattus norvegicus 58210 R-RNO-202110 https://reactome.org/PathwayBrowser/#/R-RNO-202110 eNOS:Caveolin-1 complex binds to CaM IEA Rattus norvegicus 58210 R-RNO-202111 https://reactome.org/PathwayBrowser/#/R-RNO-202111 AKT1 phosphorylates eNOS IEA Rattus norvegicus 58210 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 58210 R-RNO-202129 https://reactome.org/PathwayBrowser/#/R-RNO-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Rattus norvegicus 58210 R-RNO-202132 https://reactome.org/PathwayBrowser/#/R-RNO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Rattus norvegicus 58210 R-RNO-202137 https://reactome.org/PathwayBrowser/#/R-RNO-202137 AKT1 binds eNOS complex via HSP90 IEA Rattus norvegicus 58210 R-RNO-202144 https://reactome.org/PathwayBrowser/#/R-RNO-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Rattus norvegicus 58210 R-RNO-203553 https://reactome.org/PathwayBrowser/#/R-RNO-203553 eNOS binds NOSIP IEA Rattus norvegicus 58210 R-RNO-203613 https://reactome.org/PathwayBrowser/#/R-RNO-203613 depalmitoylation of eNOS IEA Rattus norvegicus 58210 R-RNO-203625 https://reactome.org/PathwayBrowser/#/R-RNO-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Rattus norvegicus 58210 R-RNO-203662 https://reactome.org/PathwayBrowser/#/R-RNO-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Rattus norvegicus 58210 R-RNO-203680 https://reactome.org/PathwayBrowser/#/R-RNO-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Rattus norvegicus 58210 R-RNO-203700 https://reactome.org/PathwayBrowser/#/R-RNO-203700 eNOS translocation from Golgi to Caveolae IEA Rattus norvegicus 58210 R-RNO-203712 https://reactome.org/PathwayBrowser/#/R-RNO-203712 eNOS associates with Caveolin-1 IEA Rattus norvegicus 58210 R-RNO-203716 https://reactome.org/PathwayBrowser/#/R-RNO-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Rattus norvegicus 58210 R-RNO-209921 https://reactome.org/PathwayBrowser/#/R-RNO-209921 Monoiodinated tyrosine can be deiodinated IEA Rattus norvegicus 58210 R-RNO-209960 https://reactome.org/PathwayBrowser/#/R-RNO-209960 Diiodinated tyrosine can be deiodinated IEA Rattus norvegicus 58210 R-RNO-3149518 https://reactome.org/PathwayBrowser/#/R-RNO-3149518 MTRR reduces cob(II)alamin to meCbl IEA Rattus norvegicus 58210 R-RNO-3149539 https://reactome.org/PathwayBrowser/#/R-RNO-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Rattus norvegicus 58210 R-RNO-3165230 https://reactome.org/PathwayBrowser/#/R-RNO-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Rattus norvegicus 58210 R-RNO-3204318 https://reactome.org/PathwayBrowser/#/R-RNO-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Rattus norvegicus 58210 R-RNO-389842 https://reactome.org/PathwayBrowser/#/R-RNO-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Rattus norvegicus 58210 R-RNO-389862 https://reactome.org/PathwayBrowser/#/R-RNO-389862 Conversion of glyoxylate to oxalate IEA Rattus norvegicus 58210 R-RNO-6788556 https://reactome.org/PathwayBrowser/#/R-RNO-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Rattus norvegicus 58210 R-RNO-6799179 https://reactome.org/PathwayBrowser/#/R-RNO-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Rattus norvegicus 58210 R-RNO-6799196 https://reactome.org/PathwayBrowser/#/R-RNO-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Rattus norvegicus 58210 R-RNO-6800870 https://reactome.org/PathwayBrowser/#/R-RNO-6800870 NDUF subunits bind to form the FP subcomplex IEA Rattus norvegicus 58210 R-RNO-73569 https://reactome.org/PathwayBrowser/#/R-RNO-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Rattus norvegicus 58210 R-RNO-73585 https://reactome.org/PathwayBrowser/#/R-RNO-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Rattus norvegicus 58210 R-RNO-73616 https://reactome.org/PathwayBrowser/#/R-RNO-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Rattus norvegicus 58210 R-RNO-965019 https://reactome.org/PathwayBrowser/#/R-RNO-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Rattus norvegicus 58210 R-RNO-965079 https://reactome.org/PathwayBrowser/#/R-RNO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Rattus norvegicus 58210 R-RNO-9708759 https://reactome.org/PathwayBrowser/#/R-RNO-9708759 DHODH:FMN binds DHODH inhibitors IEA Rattus norvegicus 58210 R-SCE-1497784 https://reactome.org/PathwayBrowser/#/R-SCE-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Saccharomyces cerevisiae 58210 R-SCE-1497796 https://reactome.org/PathwayBrowser/#/R-SCE-1497796 BH2 binding can lead to eNOS uncoupling IEA Saccharomyces cerevisiae 58210 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 58210 R-SCE-196840 https://reactome.org/PathwayBrowser/#/R-SCE-196840 3xPPCDC:3FMN decarboxylates PPC IEA Saccharomyces cerevisiae 58210 R-SCE-196929 https://reactome.org/PathwayBrowser/#/R-SCE-196929 FLAD1 phosphorylates FMN IEA Saccharomyces cerevisiae 58210 R-SCE-196955 https://reactome.org/PathwayBrowser/#/R-SCE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Saccharomyces cerevisiae 58210 R-SCE-196964 https://reactome.org/PathwayBrowser/#/R-SCE-196964 RFK:Mg2+ phosphorylates RIB IEA Saccharomyces cerevisiae 58210 R-SCE-202111 https://reactome.org/PathwayBrowser/#/R-SCE-202111 AKT1 phosphorylates eNOS IEA Saccharomyces cerevisiae 58210 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 58210 R-SCE-202132 https://reactome.org/PathwayBrowser/#/R-SCE-202132 depalmitoylated eNOS translocates from plasma membrane IEA Saccharomyces cerevisiae 58210 R-SCE-203613 https://reactome.org/PathwayBrowser/#/R-SCE-203613 depalmitoylation of eNOS IEA Saccharomyces cerevisiae 58210 R-SCE-203700 https://reactome.org/PathwayBrowser/#/R-SCE-203700 eNOS translocation from Golgi to Caveolae IEA Saccharomyces cerevisiae 58210 R-SCE-2564819 https://reactome.org/PathwayBrowser/#/R-SCE-2564819 NADPH reduces TAH18:DRE2 TAS Saccharomyces cerevisiae 58210 R-SCE-2564822 https://reactome.org/PathwayBrowser/#/R-SCE-2564822 4Fe-4S cluster assembles on CFD1:NBP35 scaffold TAS Saccharomyces cerevisiae 58210 R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 58210 R-SCE-965019 https://reactome.org/PathwayBrowser/#/R-SCE-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Saccharomyces cerevisiae 58210 R-SCE-965079 https://reactome.org/PathwayBrowser/#/R-SCE-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Saccharomyces cerevisiae 58210 R-SPO-1497784 https://reactome.org/PathwayBrowser/#/R-SPO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Schizosaccharomyces pombe 58210 R-SPO-1497796 https://reactome.org/PathwayBrowser/#/R-SPO-1497796 BH2 binding can lead to eNOS uncoupling IEA Schizosaccharomyces pombe 58210 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 58210 R-SPO-196929 https://reactome.org/PathwayBrowser/#/R-SPO-196929 FLAD1 phosphorylates FMN IEA Schizosaccharomyces pombe 58210 R-SPO-196955 https://reactome.org/PathwayBrowser/#/R-SPO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Schizosaccharomyces pombe 58210 R-SPO-196964 https://reactome.org/PathwayBrowser/#/R-SPO-196964 RFK:Mg2+ phosphorylates RIB IEA Schizosaccharomyces pombe 58210 R-SPO-202111 https://reactome.org/PathwayBrowser/#/R-SPO-202111 AKT1 phosphorylates eNOS IEA Schizosaccharomyces pombe 58210 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 58210 R-SPO-202132 https://reactome.org/PathwayBrowser/#/R-SPO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Schizosaccharomyces pombe 58210 R-SPO-202137 https://reactome.org/PathwayBrowser/#/R-SPO-202137 AKT1 binds eNOS complex via HSP90 IEA Schizosaccharomyces pombe 58210 R-SPO-203613 https://reactome.org/PathwayBrowser/#/R-SPO-203613 depalmitoylation of eNOS IEA Schizosaccharomyces pombe 58210 R-SPO-203700 https://reactome.org/PathwayBrowser/#/R-SPO-203700 eNOS translocation from Golgi to Caveolae IEA Schizosaccharomyces pombe 58210 R-SPO-73569 https://reactome.org/PathwayBrowser/#/R-SPO-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Schizosaccharomyces pombe 58210 R-SPO-965019 https://reactome.org/PathwayBrowser/#/R-SPO-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Schizosaccharomyces pombe 58210 R-SPO-965079 https://reactome.org/PathwayBrowser/#/R-SPO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Schizosaccharomyces pombe 58210 R-SPO-9708759 https://reactome.org/PathwayBrowser/#/R-SPO-9708759 DHODH:FMN binds DHODH inhibitors IEA Schizosaccharomyces pombe 58210 R-SSC-1497784 https://reactome.org/PathwayBrowser/#/R-SSC-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Sus scrofa 58210 R-SSC-1497796 https://reactome.org/PathwayBrowser/#/R-SSC-1497796 BH2 binding can lead to eNOS uncoupling IEA Sus scrofa 58210 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 58210 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Sus scrofa 58210 R-SSC-174374 https://reactome.org/PathwayBrowser/#/R-SSC-174374 MTR transfers CH3 from MeCbl to HCYS IEA Sus scrofa 58210 R-SSC-196840 https://reactome.org/PathwayBrowser/#/R-SSC-196840 3xPPCDC:3FMN decarboxylates PPC IEA Sus scrofa 58210 R-SSC-196929 https://reactome.org/PathwayBrowser/#/R-SSC-196929 FLAD1 phosphorylates FMN IEA Sus scrofa 58210 R-SSC-196950 https://reactome.org/PathwayBrowser/#/R-SSC-196950 2xTRAP hydrolyzes FMN to RIB IEA Sus scrofa 58210 R-SSC-196955 https://reactome.org/PathwayBrowser/#/R-SSC-196955 2xENPP1 hydrolyzes FAD to FMN IEA Sus scrofa 58210 R-SSC-196964 https://reactome.org/PathwayBrowser/#/R-SSC-196964 RFK:Mg2+ phosphorylates RIB IEA Sus scrofa 58210 R-SSC-202110 https://reactome.org/PathwayBrowser/#/R-SSC-202110 eNOS:Caveolin-1 complex binds to CaM IEA Sus scrofa 58210 R-SSC-202111 https://reactome.org/PathwayBrowser/#/R-SSC-202111 AKT1 phosphorylates eNOS IEA Sus scrofa 58210 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 58210 R-SSC-202129 https://reactome.org/PathwayBrowser/#/R-SSC-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Sus scrofa 58210 R-SSC-202132 https://reactome.org/PathwayBrowser/#/R-SSC-202132 depalmitoylated eNOS translocates from plasma membrane IEA Sus scrofa 58210 R-SSC-202144 https://reactome.org/PathwayBrowser/#/R-SSC-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Sus scrofa 58210 R-SSC-203553 https://reactome.org/PathwayBrowser/#/R-SSC-203553 eNOS binds NOSIP IEA Sus scrofa 58210 R-SSC-203565 https://reactome.org/PathwayBrowser/#/R-SSC-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Sus scrofa 58210 R-SSC-203613 https://reactome.org/PathwayBrowser/#/R-SSC-203613 depalmitoylation of eNOS IEA Sus scrofa 58210 R-SSC-203625 https://reactome.org/PathwayBrowser/#/R-SSC-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Sus scrofa 58210 R-SSC-203662 https://reactome.org/PathwayBrowser/#/R-SSC-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Sus scrofa 58210 R-SSC-203680 https://reactome.org/PathwayBrowser/#/R-SSC-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Sus scrofa 58210 R-SSC-203700 https://reactome.org/PathwayBrowser/#/R-SSC-203700 eNOS translocation from Golgi to Caveolae IEA Sus scrofa 58210 R-SSC-203712 https://reactome.org/PathwayBrowser/#/R-SSC-203712 eNOS associates with Caveolin-1 IEA Sus scrofa 58210 R-SSC-203716 https://reactome.org/PathwayBrowser/#/R-SSC-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Sus scrofa 58210 R-SSC-209921 https://reactome.org/PathwayBrowser/#/R-SSC-209921 Monoiodinated tyrosine can be deiodinated IEA Sus scrofa 58210 R-SSC-209960 https://reactome.org/PathwayBrowser/#/R-SSC-209960 Diiodinated tyrosine can be deiodinated IEA Sus scrofa 58210 R-SSC-3149518 https://reactome.org/PathwayBrowser/#/R-SSC-3149518 MTRR reduces cob(II)alamin to meCbl IEA Sus scrofa 58210 R-SSC-3149539 https://reactome.org/PathwayBrowser/#/R-SSC-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Sus scrofa 58210 R-SSC-3165230 https://reactome.org/PathwayBrowser/#/R-SSC-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Sus scrofa 58210 R-SSC-3204318 https://reactome.org/PathwayBrowser/#/R-SSC-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Sus scrofa 58210 R-SSC-389842 https://reactome.org/PathwayBrowser/#/R-SSC-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Sus scrofa 58210 R-SSC-389862 https://reactome.org/PathwayBrowser/#/R-SSC-389862 Conversion of glyoxylate to oxalate IEA Sus scrofa 58210 R-SSC-6788556 https://reactome.org/PathwayBrowser/#/R-SSC-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Sus scrofa 58210 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa 58210 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa 58210 R-SSC-73569 https://reactome.org/PathwayBrowser/#/R-SSC-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Sus scrofa 58210 R-SSC-73585 https://reactome.org/PathwayBrowser/#/R-SSC-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Sus scrofa 58210 R-SSC-73616 https://reactome.org/PathwayBrowser/#/R-SSC-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Sus scrofa 58210 R-SSC-965019 https://reactome.org/PathwayBrowser/#/R-SSC-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Sus scrofa 58210 R-SSC-965079 https://reactome.org/PathwayBrowser/#/R-SSC-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Sus scrofa 58210 R-SSC-9708759 https://reactome.org/PathwayBrowser/#/R-SSC-9708759 DHODH:FMN binds DHODH inhibitors IEA Sus scrofa 58210 R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Xenopus tropicalis 58210 R-XTR-196840 https://reactome.org/PathwayBrowser/#/R-XTR-196840 3xPPCDC:3FMN decarboxylates PPC IEA Xenopus tropicalis 58210 R-XTR-196955 https://reactome.org/PathwayBrowser/#/R-XTR-196955 2xENPP1 hydrolyzes FAD to FMN IEA Xenopus tropicalis 58210 R-XTR-196964 https://reactome.org/PathwayBrowser/#/R-XTR-196964 RFK:Mg2+ phosphorylates RIB IEA Xenopus tropicalis 58210 R-XTR-209921 https://reactome.org/PathwayBrowser/#/R-XTR-209921 Monoiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 58210 R-XTR-209960 https://reactome.org/PathwayBrowser/#/R-XTR-209960 Diiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 58210 R-XTR-3165230 https://reactome.org/PathwayBrowser/#/R-XTR-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol IEA Xenopus tropicalis 58210 R-XTR-389842 https://reactome.org/PathwayBrowser/#/R-XTR-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Xenopus tropicalis 58210 R-XTR-389862 https://reactome.org/PathwayBrowser/#/R-XTR-389862 Conversion of glyoxylate to oxalate IEA Xenopus tropicalis 58210 R-XTR-6788556 https://reactome.org/PathwayBrowser/#/R-XTR-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Xenopus tropicalis 58210 R-XTR-73569 https://reactome.org/PathwayBrowser/#/R-XTR-73569 DHODH:FMN oxidises (S)-DHO to orotate IEA Xenopus tropicalis 58210 R-XTR-73585 https://reactome.org/PathwayBrowser/#/R-XTR-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Xenopus tropicalis 58210 R-XTR-73616 https://reactome.org/PathwayBrowser/#/R-XTR-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Xenopus tropicalis 58210 R-XTR-965019 https://reactome.org/PathwayBrowser/#/R-XTR-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Xenopus tropicalis 58210 R-XTR-965079 https://reactome.org/PathwayBrowser/#/R-XTR-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Xenopus tropicalis 58210 R-XTR-9708759 https://reactome.org/PathwayBrowser/#/R-XTR-9708759 DHODH:FMN binds DHODH inhibitors IEA Xenopus tropicalis 58223 R-BTA-158546 https://reactome.org/PathwayBrowser/#/R-BTA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Bos taurus 58223 R-BTA-162730 https://reactome.org/PathwayBrowser/#/R-BTA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Bos taurus 58223 R-BTA-1638104 https://reactome.org/PathwayBrowser/#/R-BTA-1638104 UGCG transfers glucose to ceramide IEA Bos taurus 58223 R-BTA-1878002 https://reactome.org/PathwayBrowser/#/R-BTA-1878002 XYLTs transfer Xyl to core protein IEA Bos taurus 58223 R-BTA-1889955 https://reactome.org/PathwayBrowser/#/R-BTA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Bos taurus 58223 R-BTA-1889978 https://reactome.org/PathwayBrowser/#/R-BTA-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Bos taurus 58223 R-BTA-1889981 https://reactome.org/PathwayBrowser/#/R-BTA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Bos taurus 58223 R-BTA-1964501 https://reactome.org/PathwayBrowser/#/R-BTA-1964501 Addition of galactose to Core 6 glycoprotein IEA Bos taurus 58223 R-BTA-1964505 https://reactome.org/PathwayBrowser/#/R-BTA-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Bos taurus 58223 R-BTA-1971482 https://reactome.org/PathwayBrowser/#/R-BTA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Bos taurus 58223 R-BTA-1971487 https://reactome.org/PathwayBrowser/#/R-BTA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Bos taurus 58223 R-BTA-1971491 https://reactome.org/PathwayBrowser/#/R-BTA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Bos taurus 58223 R-BTA-2022851 https://reactome.org/PathwayBrowser/#/R-BTA-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Bos taurus 58223 R-BTA-2022856 https://reactome.org/PathwayBrowser/#/R-BTA-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Bos taurus 58223 R-BTA-2022919 https://reactome.org/PathwayBrowser/#/R-BTA-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Bos taurus 58223 R-BTA-2025723 https://reactome.org/PathwayBrowser/#/R-BTA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Bos taurus 58223 R-BTA-2025724 https://reactome.org/PathwayBrowser/#/R-BTA-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Bos taurus 58223 R-BTA-2046265 https://reactome.org/PathwayBrowser/#/R-BTA-2046265 B4GALTs transfer Gal to the keratan chain IEA Bos taurus 58223 R-BTA-2046298 https://reactome.org/PathwayBrowser/#/R-BTA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Bos taurus 58223 R-BTA-2076392 https://reactome.org/PathwayBrowser/#/R-BTA-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Bos taurus 58223 R-BTA-3322001 https://reactome.org/PathwayBrowser/#/R-BTA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Bos taurus 58223 R-BTA-3322003 https://reactome.org/PathwayBrowser/#/R-BTA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Bos taurus 58223 R-BTA-3322009 https://reactome.org/PathwayBrowser/#/R-BTA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Bos taurus 58223 R-BTA-3322014 https://reactome.org/PathwayBrowser/#/R-BTA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Bos taurus 58223 R-BTA-3322019 https://reactome.org/PathwayBrowser/#/R-BTA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Bos taurus 58223 R-BTA-3322025 https://reactome.org/PathwayBrowser/#/R-BTA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Bos taurus 58223 R-BTA-3322041 https://reactome.org/PathwayBrowser/#/R-BTA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Bos taurus 58223 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 58223 R-BTA-4085021 https://reactome.org/PathwayBrowser/#/R-BTA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Bos taurus 58223 R-BTA-417896 https://reactome.org/PathwayBrowser/#/R-BTA-417896 P2Y6 receptor can bind to UDP IEA Bos taurus 58223 R-BTA-418918 https://reactome.org/PathwayBrowser/#/R-BTA-418918 The UDP/CysLT (P2Y17) receptor can bind UTP IEA Bos taurus 58223 R-BTA-446207 https://reactome.org/PathwayBrowser/#/R-BTA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Bos taurus 58223 R-BTA-446214 https://reactome.org/PathwayBrowser/#/R-BTA-446214 Synthesis of dolichyl-phosphate-glucose IEA Bos taurus 58223 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 58223 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 58223 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 58223 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 58223 R-BTA-5617037 https://reactome.org/PathwayBrowser/#/R-BTA-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Bos taurus 58223 R-BTA-5617138 https://reactome.org/PathwayBrowser/#/R-BTA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Bos taurus 58223 R-BTA-5617143 https://reactome.org/PathwayBrowser/#/R-BTA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Bos taurus 58223 R-BTA-5653878 https://reactome.org/PathwayBrowser/#/R-BTA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Bos taurus 58223 R-BTA-5694487 https://reactome.org/PathwayBrowser/#/R-BTA-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Bos taurus 58223 R-BTA-73548 https://reactome.org/PathwayBrowser/#/R-BTA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Bos taurus 58223 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 58223 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 58223 R-BTA-75125 https://reactome.org/PathwayBrowser/#/R-BTA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Bos taurus 58223 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 58223 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 58223 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 58223 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 58223 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 58223 R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 58223 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 58223 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 58223 R-BTA-8851619 https://reactome.org/PathwayBrowser/#/R-BTA-8851619 GALNT3 transfers GalNAc to FGF23 IEA Bos taurus 58223 R-BTA-8855954 https://reactome.org/PathwayBrowser/#/R-BTA-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Bos taurus 58223 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 58223 R-BTA-9033959 https://reactome.org/PathwayBrowser/#/R-BTA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Bos taurus 58223 R-BTA-9033961 https://reactome.org/PathwayBrowser/#/R-BTA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Bos taurus 58223 R-BTA-9034042 https://reactome.org/PathwayBrowser/#/R-BTA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Bos taurus 58223 R-BTA-9034053 https://reactome.org/PathwayBrowser/#/R-BTA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Bos taurus 58223 R-BTA-913675 https://reactome.org/PathwayBrowser/#/R-BTA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Bos taurus 58223 R-BTA-914005 https://reactome.org/PathwayBrowser/#/R-BTA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Bos taurus 58223 R-BTA-914006 https://reactome.org/PathwayBrowser/#/R-BTA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Bos taurus 58223 R-BTA-914008 https://reactome.org/PathwayBrowser/#/R-BTA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Bos taurus 58223 R-BTA-914010 https://reactome.org/PathwayBrowser/#/R-BTA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Bos taurus 58223 R-BTA-914012 https://reactome.org/PathwayBrowser/#/R-BTA-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Bos taurus 58223 R-BTA-914017 https://reactome.org/PathwayBrowser/#/R-BTA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Bos taurus 58223 R-BTA-914018 https://reactome.org/PathwayBrowser/#/R-BTA-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Bos taurus 58223 R-BTA-9603989 https://reactome.org/PathwayBrowser/#/R-BTA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Bos taurus 58223 R-BTA-9605700 https://reactome.org/PathwayBrowser/#/R-BTA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Bos taurus 58223 R-BTA-9632033 https://reactome.org/PathwayBrowser/#/R-BTA-9632033 CHSY1 transfers GalNAc to chondroitin IEA Bos taurus 58223 R-BTA-9632034 https://reactome.org/PathwayBrowser/#/R-BTA-9632034 CHSY1 transfers GlcA to chondroitin IEA Bos taurus 58223 R-BTA-9638064 https://reactome.org/PathwayBrowser/#/R-BTA-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Bos taurus 58223 R-BTA-9638090 https://reactome.org/PathwayBrowser/#/R-BTA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Bos taurus 58223 R-BTA-9638097 https://reactome.org/PathwayBrowser/#/R-BTA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Bos taurus 58223 R-BTA-964768 https://reactome.org/PathwayBrowser/#/R-BTA-964768 Addition of GlcNAc to the glycan on the A arm IEA Bos taurus 58223 R-BTA-9687828 https://reactome.org/PathwayBrowser/#/R-BTA-9687828 O-GlcNAcylation of RIPK3 (TLR4 signaling) IEA Bos taurus 58223 R-BTA-9756134 https://reactome.org/PathwayBrowser/#/R-BTA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Bos taurus 58223 R-BTA-9756156 https://reactome.org/PathwayBrowser/#/R-BTA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Bos taurus 58223 R-BTA-9756183 https://reactome.org/PathwayBrowser/#/R-BTA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Bos taurus 58223 R-BTA-975829 https://reactome.org/PathwayBrowser/#/R-BTA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Bos taurus 58223 R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 58223 R-BTA-9845516 https://reactome.org/PathwayBrowser/#/R-BTA-9845516 B3GALT4 transfers Gal to gangliosides IEA Bos taurus 58223 R-BTA-9846477 https://reactome.org/PathwayBrowser/#/R-BTA-9846477 A4GALT transfers galactose to LacCer IEA Bos taurus 58223 R-BTA-9846501 https://reactome.org/PathwayBrowser/#/R-BTA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Bos taurus 58223 R-BTA-9851347 https://reactome.org/PathwayBrowser/#/R-BTA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Bos taurus 58223 R-CEL-158546 https://reactome.org/PathwayBrowser/#/R-CEL-158546 UGTs glucuronate APAP to APAP-GlcA IEA Caenorhabditis elegans 58223 R-CEL-1638104 https://reactome.org/PathwayBrowser/#/R-CEL-1638104 UGCG transfers glucose to ceramide IEA Caenorhabditis elegans 58223 R-CEL-1878002 https://reactome.org/PathwayBrowser/#/R-CEL-1878002 XYLTs transfer Xyl to core protein IEA Caenorhabditis elegans 58223 R-CEL-1889955 https://reactome.org/PathwayBrowser/#/R-CEL-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Caenorhabditis elegans 58223 R-CEL-1889978 https://reactome.org/PathwayBrowser/#/R-CEL-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Caenorhabditis elegans 58223 R-CEL-1889981 https://reactome.org/PathwayBrowser/#/R-CEL-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Caenorhabditis elegans 58223 R-CEL-1964505 https://reactome.org/PathwayBrowser/#/R-CEL-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Caenorhabditis elegans 58223 R-CEL-3322001 https://reactome.org/PathwayBrowser/#/R-CEL-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Caenorhabditis elegans 58223 R-CEL-3322003 https://reactome.org/PathwayBrowser/#/R-CEL-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Caenorhabditis elegans 58223 R-CEL-3322009 https://reactome.org/PathwayBrowser/#/R-CEL-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Caenorhabditis elegans 58223 R-CEL-3322014 https://reactome.org/PathwayBrowser/#/R-CEL-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Caenorhabditis elegans 58223 R-CEL-3322019 https://reactome.org/PathwayBrowser/#/R-CEL-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Caenorhabditis elegans 58223 R-CEL-3322025 https://reactome.org/PathwayBrowser/#/R-CEL-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Caenorhabditis elegans 58223 R-CEL-3322041 https://reactome.org/PathwayBrowser/#/R-CEL-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Caenorhabditis elegans 58223 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 58223 R-CEL-418918 https://reactome.org/PathwayBrowser/#/R-CEL-418918 The UDP/CysLT (P2Y17) receptor can bind UTP IEA Caenorhabditis elegans 58223 R-CEL-446207 https://reactome.org/PathwayBrowser/#/R-CEL-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Caenorhabditis elegans 58223 R-CEL-446214 https://reactome.org/PathwayBrowser/#/R-CEL-446214 Synthesis of dolichyl-phosphate-glucose IEA Caenorhabditis elegans 58223 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 58223 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 58223 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 58223 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 58223 R-CEL-73548 https://reactome.org/PathwayBrowser/#/R-CEL-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Caenorhabditis elegans 58223 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 58223 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 58223 R-CEL-75125 https://reactome.org/PathwayBrowser/#/R-CEL-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Caenorhabditis elegans 58223 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58223 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 58223 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58223 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58223 R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 58223 R-CEL-913675 https://reactome.org/PathwayBrowser/#/R-CEL-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Caenorhabditis elegans 58223 R-CEL-914005 https://reactome.org/PathwayBrowser/#/R-CEL-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Caenorhabditis elegans 58223 R-CEL-914006 https://reactome.org/PathwayBrowser/#/R-CEL-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Caenorhabditis elegans 58223 R-CEL-914008 https://reactome.org/PathwayBrowser/#/R-CEL-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Caenorhabditis elegans 58223 R-CEL-914012 https://reactome.org/PathwayBrowser/#/R-CEL-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Caenorhabditis elegans 58223 R-CEL-914017 https://reactome.org/PathwayBrowser/#/R-CEL-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Caenorhabditis elegans 58223 R-CEL-914018 https://reactome.org/PathwayBrowser/#/R-CEL-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Caenorhabditis elegans 58223 R-CEL-9603989 https://reactome.org/PathwayBrowser/#/R-CEL-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Caenorhabditis elegans 58223 R-CEL-9638064 https://reactome.org/PathwayBrowser/#/R-CEL-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Caenorhabditis elegans 58223 R-CEL-964768 https://reactome.org/PathwayBrowser/#/R-CEL-964768 Addition of GlcNAc to the glycan on the A arm IEA Caenorhabditis elegans 58223 R-CEL-975829 https://reactome.org/PathwayBrowser/#/R-CEL-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Caenorhabditis elegans 58223 R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 58223 R-CEL-9845516 https://reactome.org/PathwayBrowser/#/R-CEL-9845516 B3GALT4 transfers Gal to gangliosides IEA Caenorhabditis elegans 58223 R-CFA-158546 https://reactome.org/PathwayBrowser/#/R-CFA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Canis familiaris 58223 R-CFA-1638104 https://reactome.org/PathwayBrowser/#/R-CFA-1638104 UGCG transfers glucose to ceramide IEA Canis familiaris 58223 R-CFA-1878002 https://reactome.org/PathwayBrowser/#/R-CFA-1878002 XYLTs transfer Xyl to core protein IEA Canis familiaris 58223 R-CFA-1889955 https://reactome.org/PathwayBrowser/#/R-CFA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Canis familiaris 58223 R-CFA-1889978 https://reactome.org/PathwayBrowser/#/R-CFA-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Canis familiaris 58223 R-CFA-1889981 https://reactome.org/PathwayBrowser/#/R-CFA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Canis familiaris 58223 R-CFA-1964501 https://reactome.org/PathwayBrowser/#/R-CFA-1964501 Addition of galactose to Core 6 glycoprotein IEA Canis familiaris 58223 R-CFA-1964505 https://reactome.org/PathwayBrowser/#/R-CFA-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Canis familiaris 58223 R-CFA-1971482 https://reactome.org/PathwayBrowser/#/R-CFA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Canis familiaris 58223 R-CFA-1971487 https://reactome.org/PathwayBrowser/#/R-CFA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Canis familiaris 58223 R-CFA-1971491 https://reactome.org/PathwayBrowser/#/R-CFA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Canis familiaris 58223 R-CFA-2022851 https://reactome.org/PathwayBrowser/#/R-CFA-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Canis familiaris 58223 R-CFA-2022856 https://reactome.org/PathwayBrowser/#/R-CFA-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Canis familiaris 58223 R-CFA-2022919 https://reactome.org/PathwayBrowser/#/R-CFA-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Canis familiaris 58223 R-CFA-2025723 https://reactome.org/PathwayBrowser/#/R-CFA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Canis familiaris 58223 R-CFA-2025724 https://reactome.org/PathwayBrowser/#/R-CFA-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Canis familiaris 58223 R-CFA-2046265 https://reactome.org/PathwayBrowser/#/R-CFA-2046265 B4GALTs transfer Gal to the keratan chain IEA Canis familiaris 58223 R-CFA-2046298 https://reactome.org/PathwayBrowser/#/R-CFA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Canis familiaris 58223 R-CFA-2076392 https://reactome.org/PathwayBrowser/#/R-CFA-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Canis familiaris 58223 R-CFA-3322001 https://reactome.org/PathwayBrowser/#/R-CFA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Canis familiaris 58223 R-CFA-3322003 https://reactome.org/PathwayBrowser/#/R-CFA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Canis familiaris 58223 R-CFA-3322009 https://reactome.org/PathwayBrowser/#/R-CFA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Canis familiaris 58223 R-CFA-3322014 https://reactome.org/PathwayBrowser/#/R-CFA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Canis familiaris 58223 R-CFA-3322019 https://reactome.org/PathwayBrowser/#/R-CFA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Canis familiaris 58223 R-CFA-3322025 https://reactome.org/PathwayBrowser/#/R-CFA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Canis familiaris 58223 R-CFA-3322041 https://reactome.org/PathwayBrowser/#/R-CFA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Canis familiaris 58223 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 58223 R-CFA-4085021 https://reactome.org/PathwayBrowser/#/R-CFA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Canis familiaris 58223 R-CFA-417896 https://reactome.org/PathwayBrowser/#/R-CFA-417896 P2Y6 receptor can bind to UDP IEA Canis familiaris 58223 R-CFA-418918 https://reactome.org/PathwayBrowser/#/R-CFA-418918 The UDP/CysLT (P2Y17) receptor can bind UTP IEA Canis familiaris 58223 R-CFA-446207 https://reactome.org/PathwayBrowser/#/R-CFA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Canis familiaris 58223 R-CFA-446214 https://reactome.org/PathwayBrowser/#/R-CFA-446214 Synthesis of dolichyl-phosphate-glucose IEA Canis familiaris 58223 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 58223 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 58223 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 58223 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 58223 R-CFA-5617037 https://reactome.org/PathwayBrowser/#/R-CFA-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Canis familiaris 58223 R-CFA-5617138 https://reactome.org/PathwayBrowser/#/R-CFA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Canis familiaris 58223 R-CFA-5617143 https://reactome.org/PathwayBrowser/#/R-CFA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Canis familiaris 58223 R-CFA-5653878 https://reactome.org/PathwayBrowser/#/R-CFA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Canis familiaris 58223 R-CFA-5694487 https://reactome.org/PathwayBrowser/#/R-CFA-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Canis familiaris 58223 R-CFA-73548 https://reactome.org/PathwayBrowser/#/R-CFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Canis familiaris 58223 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 58223 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 58223 R-CFA-75125 https://reactome.org/PathwayBrowser/#/R-CFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Canis familiaris 58223 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58223 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58223 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58223 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58223 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58223 R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58223 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58223 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58223 R-CFA-8851619 https://reactome.org/PathwayBrowser/#/R-CFA-8851619 GALNT3 transfers GalNAc to FGF23 IEA Canis familiaris 58223 R-CFA-8855954 https://reactome.org/PathwayBrowser/#/R-CFA-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Canis familiaris 58223 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 58223 R-CFA-8878914 https://reactome.org/PathwayBrowser/#/R-CFA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Canis familiaris 58223 R-CFA-9033959 https://reactome.org/PathwayBrowser/#/R-CFA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Canis familiaris 58223 R-CFA-9033961 https://reactome.org/PathwayBrowser/#/R-CFA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Canis familiaris 58223 R-CFA-9034042 https://reactome.org/PathwayBrowser/#/R-CFA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Canis familiaris 58223 R-CFA-9034053 https://reactome.org/PathwayBrowser/#/R-CFA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Canis familiaris 58223 R-CFA-913675 https://reactome.org/PathwayBrowser/#/R-CFA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Canis familiaris 58223 R-CFA-914005 https://reactome.org/PathwayBrowser/#/R-CFA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Canis familiaris 58223 R-CFA-914006 https://reactome.org/PathwayBrowser/#/R-CFA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Canis familiaris 58223 R-CFA-914008 https://reactome.org/PathwayBrowser/#/R-CFA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Canis familiaris 58223 R-CFA-914010 https://reactome.org/PathwayBrowser/#/R-CFA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Canis familiaris 58223 R-CFA-914012 https://reactome.org/PathwayBrowser/#/R-CFA-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Canis familiaris 58223 R-CFA-914017 https://reactome.org/PathwayBrowser/#/R-CFA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Canis familiaris 58223 R-CFA-914018 https://reactome.org/PathwayBrowser/#/R-CFA-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Canis familiaris 58223 R-CFA-9603989 https://reactome.org/PathwayBrowser/#/R-CFA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Canis familiaris 58223 R-CFA-9605700 https://reactome.org/PathwayBrowser/#/R-CFA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Canis familiaris 58223 R-CFA-9632033 https://reactome.org/PathwayBrowser/#/R-CFA-9632033 CHSY1 transfers GalNAc to chondroitin IEA Canis familiaris 58223 R-CFA-9632034 https://reactome.org/PathwayBrowser/#/R-CFA-9632034 CHSY1 transfers GlcA to chondroitin IEA Canis familiaris 58223 R-CFA-9638064 https://reactome.org/PathwayBrowser/#/R-CFA-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Canis familiaris 58223 R-CFA-9638090 https://reactome.org/PathwayBrowser/#/R-CFA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Canis familiaris 58223 R-CFA-9638097 https://reactome.org/PathwayBrowser/#/R-CFA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Canis familiaris 58223 R-CFA-9687828 https://reactome.org/PathwayBrowser/#/R-CFA-9687828 O-GlcNAcylation of RIPK3 (TLR4 signaling) IEA Canis familiaris 58223 R-CFA-975829 https://reactome.org/PathwayBrowser/#/R-CFA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Canis familiaris 58223 R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 58223 R-CFA-9845516 https://reactome.org/PathwayBrowser/#/R-CFA-9845516 B3GALT4 transfers Gal to gangliosides IEA Canis familiaris 58223 R-CFA-9846477 https://reactome.org/PathwayBrowser/#/R-CFA-9846477 A4GALT transfers galactose to LacCer IEA Canis familiaris 58223 R-CFA-9851347 https://reactome.org/PathwayBrowser/#/R-CFA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Canis familiaris 58223 R-CGR-2032355 https://reactome.org/PathwayBrowser/#/R-CGR-2032355 Galactosylation of Pre-Notch TAS Cricetulus griseus 58223 R-DDI-158546 https://reactome.org/PathwayBrowser/#/R-DDI-158546 UGTs glucuronate APAP to APAP-GlcA IEA Dictyostelium discoideum 58223 R-DDI-3322001 https://reactome.org/PathwayBrowser/#/R-DDI-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Dictyostelium discoideum 58223 R-DDI-3322003 https://reactome.org/PathwayBrowser/#/R-DDI-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Dictyostelium discoideum 58223 R-DDI-3322009 https://reactome.org/PathwayBrowser/#/R-DDI-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Dictyostelium discoideum 58223 R-DDI-3322014 https://reactome.org/PathwayBrowser/#/R-DDI-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Dictyostelium discoideum 58223 R-DDI-3322019 https://reactome.org/PathwayBrowser/#/R-DDI-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Dictyostelium discoideum 58223 R-DDI-3322025 https://reactome.org/PathwayBrowser/#/R-DDI-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Dictyostelium discoideum 58223 R-DDI-3322041 https://reactome.org/PathwayBrowser/#/R-DDI-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Dictyostelium discoideum 58223 R-DDI-446214 https://reactome.org/PathwayBrowser/#/R-DDI-446214 Synthesis of dolichyl-phosphate-glucose IEA Dictyostelium discoideum 58223 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 58223 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 58223 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 58223 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 58223 R-DDI-73548 https://reactome.org/PathwayBrowser/#/R-DDI-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Dictyostelium discoideum 58223 R-DDI-75125 https://reactome.org/PathwayBrowser/#/R-DDI-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Dictyostelium discoideum 58223 R-DDI-914005 https://reactome.org/PathwayBrowser/#/R-DDI-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Dictyostelium discoideum 58223 R-DDI-914006 https://reactome.org/PathwayBrowser/#/R-DDI-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Dictyostelium discoideum 58223 R-DDI-914008 https://reactome.org/PathwayBrowser/#/R-DDI-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Dictyostelium discoideum 58223 R-DDI-914017 https://reactome.org/PathwayBrowser/#/R-DDI-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Dictyostelium discoideum 58223 R-DDI-964768 https://reactome.org/PathwayBrowser/#/R-DDI-964768 Addition of GlcNAc to the glycan on the A arm IEA Dictyostelium discoideum 58223 R-DDI-9756134 https://reactome.org/PathwayBrowser/#/R-DDI-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Dictyostelium discoideum 58223 R-DDI-9756156 https://reactome.org/PathwayBrowser/#/R-DDI-9756156 UGT1A3 lactonizes ATV to ATVL IEA Dictyostelium discoideum 58223 R-DDI-9756183 https://reactome.org/PathwayBrowser/#/R-DDI-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Dictyostelium discoideum 58223 R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 58223 R-DME-158546 https://reactome.org/PathwayBrowser/#/R-DME-158546 UGTs glucuronate APAP to APAP-GlcA IEA Drosophila melanogaster 58223 R-DME-1638104 https://reactome.org/PathwayBrowser/#/R-DME-1638104 UGCG transfers glucose to ceramide IEA Drosophila melanogaster 58223 R-DME-1878002 https://reactome.org/PathwayBrowser/#/R-DME-1878002 XYLTs transfer Xyl to core protein IEA Drosophila melanogaster 58223 R-DME-1889955 https://reactome.org/PathwayBrowser/#/R-DME-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Drosophila melanogaster 58223 R-DME-1889978 https://reactome.org/PathwayBrowser/#/R-DME-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Drosophila melanogaster 58223 R-DME-1889981 https://reactome.org/PathwayBrowser/#/R-DME-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Drosophila melanogaster 58223 R-DME-1964501 https://reactome.org/PathwayBrowser/#/R-DME-1964501 Addition of galactose to Core 6 glycoprotein IEA Drosophila melanogaster 58223 R-DME-1964505 https://reactome.org/PathwayBrowser/#/R-DME-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Drosophila melanogaster 58223 R-DME-1971482 https://reactome.org/PathwayBrowser/#/R-DME-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Drosophila melanogaster 58223 R-DME-1971487 https://reactome.org/PathwayBrowser/#/R-DME-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Drosophila melanogaster 58223 R-DME-1971491 https://reactome.org/PathwayBrowser/#/R-DME-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Drosophila melanogaster 58223 R-DME-2022851 https://reactome.org/PathwayBrowser/#/R-DME-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Drosophila melanogaster 58223 R-DME-2022856 https://reactome.org/PathwayBrowser/#/R-DME-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Drosophila melanogaster 58223 R-DME-2022919 https://reactome.org/PathwayBrowser/#/R-DME-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Drosophila melanogaster 58223 R-DME-2025723 https://reactome.org/PathwayBrowser/#/R-DME-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Drosophila melanogaster 58223 R-DME-2025724 https://reactome.org/PathwayBrowser/#/R-DME-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Drosophila melanogaster 58223 R-DME-2046265 https://reactome.org/PathwayBrowser/#/R-DME-2046265 B4GALTs transfer Gal to the keratan chain IEA Drosophila melanogaster 58223 R-DME-2046298 https://reactome.org/PathwayBrowser/#/R-DME-2046298 B4GALTs transfer Gal to a branch of keratan IEA Drosophila melanogaster 58223 R-DME-2076392 https://reactome.org/PathwayBrowser/#/R-DME-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Drosophila melanogaster 58223 R-DME-3322001 https://reactome.org/PathwayBrowser/#/R-DME-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Drosophila melanogaster 58223 R-DME-3322003 https://reactome.org/PathwayBrowser/#/R-DME-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Drosophila melanogaster 58223 R-DME-3322009 https://reactome.org/PathwayBrowser/#/R-DME-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Drosophila melanogaster 58223 R-DME-3322014 https://reactome.org/PathwayBrowser/#/R-DME-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Drosophila melanogaster 58223 R-DME-3322019 https://reactome.org/PathwayBrowser/#/R-DME-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Drosophila melanogaster 58223 R-DME-3322025 https://reactome.org/PathwayBrowser/#/R-DME-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Drosophila melanogaster 58223 R-DME-3322041 https://reactome.org/PathwayBrowser/#/R-DME-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Drosophila melanogaster 58223 R-DME-446207 https://reactome.org/PathwayBrowser/#/R-DME-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Drosophila melanogaster 58223 R-DME-446214 https://reactome.org/PathwayBrowser/#/R-DME-446214 Synthesis of dolichyl-phosphate-glucose IEA Drosophila melanogaster 58223 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 58223 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 58223 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 58223 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 58223 R-DME-5653878 https://reactome.org/PathwayBrowser/#/R-DME-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Drosophila melanogaster 58223 R-DME-5694487 https://reactome.org/PathwayBrowser/#/R-DME-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Drosophila melanogaster 58223 R-DME-73548 https://reactome.org/PathwayBrowser/#/R-DME-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Drosophila melanogaster 58223 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 58223 R-DME-75125 https://reactome.org/PathwayBrowser/#/R-DME-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Drosophila melanogaster 58223 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 58223 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 58223 R-DME-8851619 https://reactome.org/PathwayBrowser/#/R-DME-8851619 GALNT3 transfers GalNAc to FGF23 IEA Drosophila melanogaster 58223 R-DME-8878914 https://reactome.org/PathwayBrowser/#/R-DME-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Drosophila melanogaster 58223 R-DME-913675 https://reactome.org/PathwayBrowser/#/R-DME-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Drosophila melanogaster 58223 R-DME-914005 https://reactome.org/PathwayBrowser/#/R-DME-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Drosophila melanogaster 58223 R-DME-914006 https://reactome.org/PathwayBrowser/#/R-DME-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Drosophila melanogaster 58223 R-DME-914008 https://reactome.org/PathwayBrowser/#/R-DME-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Drosophila melanogaster 58223 R-DME-914010 https://reactome.org/PathwayBrowser/#/R-DME-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Drosophila melanogaster 58223 R-DME-914017 https://reactome.org/PathwayBrowser/#/R-DME-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Drosophila melanogaster 58223 R-DME-9603989 https://reactome.org/PathwayBrowser/#/R-DME-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Drosophila melanogaster 58223 R-DME-9632033 https://reactome.org/PathwayBrowser/#/R-DME-9632033 CHSY1 transfers GalNAc to chondroitin IEA Drosophila melanogaster 58223 R-DME-9632034 https://reactome.org/PathwayBrowser/#/R-DME-9632034 CHSY1 transfers GlcA to chondroitin IEA Drosophila melanogaster 58223 R-DME-9638064 https://reactome.org/PathwayBrowser/#/R-DME-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Drosophila melanogaster 58223 R-DME-964768 https://reactome.org/PathwayBrowser/#/R-DME-964768 Addition of GlcNAc to the glycan on the A arm IEA Drosophila melanogaster 58223 R-DME-975829 https://reactome.org/PathwayBrowser/#/R-DME-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Drosophila melanogaster 58223 R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 58223 R-DME-9845516 https://reactome.org/PathwayBrowser/#/R-DME-9845516 B3GALT4 transfers Gal to gangliosides IEA Drosophila melanogaster 58223 R-DME-9846477 https://reactome.org/PathwayBrowser/#/R-DME-9846477 A4GALT transfers galactose to LacCer IEA Drosophila melanogaster 58223 R-DME-9846501 https://reactome.org/PathwayBrowser/#/R-DME-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Drosophila melanogaster 58223 R-DME-9851347 https://reactome.org/PathwayBrowser/#/R-DME-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Drosophila melanogaster 58223 R-DRE-158546 https://reactome.org/PathwayBrowser/#/R-DRE-158546 UGTs glucuronate APAP to APAP-GlcA IEA Danio rerio 58223 R-DRE-1638104 https://reactome.org/PathwayBrowser/#/R-DRE-1638104 UGCG transfers glucose to ceramide IEA Danio rerio 58223 R-DRE-1878002 https://reactome.org/PathwayBrowser/#/R-DRE-1878002 XYLTs transfer Xyl to core protein IEA Danio rerio 58223 R-DRE-1889955 https://reactome.org/PathwayBrowser/#/R-DRE-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Danio rerio 58223 R-DRE-1889978 https://reactome.org/PathwayBrowser/#/R-DRE-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Danio rerio 58223 R-DRE-1964501 https://reactome.org/PathwayBrowser/#/R-DRE-1964501 Addition of galactose to Core 6 glycoprotein IEA Danio rerio 58223 R-DRE-2022851 https://reactome.org/PathwayBrowser/#/R-DRE-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Danio rerio 58223 R-DRE-2022856 https://reactome.org/PathwayBrowser/#/R-DRE-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Danio rerio 58223 R-DRE-2022919 https://reactome.org/PathwayBrowser/#/R-DRE-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Danio rerio 58223 R-DRE-2025723 https://reactome.org/PathwayBrowser/#/R-DRE-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Danio rerio 58223 R-DRE-2025724 https://reactome.org/PathwayBrowser/#/R-DRE-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Danio rerio 58223 R-DRE-2046265 https://reactome.org/PathwayBrowser/#/R-DRE-2046265 B4GALTs transfer Gal to the keratan chain IEA Danio rerio 58223 R-DRE-2046298 https://reactome.org/PathwayBrowser/#/R-DRE-2046298 B4GALTs transfer Gal to a branch of keratan IEA Danio rerio 58223 R-DRE-2076392 https://reactome.org/PathwayBrowser/#/R-DRE-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Danio rerio 58223 R-DRE-3322001 https://reactome.org/PathwayBrowser/#/R-DRE-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Danio rerio 58223 R-DRE-3322003 https://reactome.org/PathwayBrowser/#/R-DRE-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Danio rerio 58223 R-DRE-3322025 https://reactome.org/PathwayBrowser/#/R-DRE-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Danio rerio 58223 R-DRE-3322041 https://reactome.org/PathwayBrowser/#/R-DRE-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Danio rerio 58223 R-DRE-4085021 https://reactome.org/PathwayBrowser/#/R-DRE-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Danio rerio 58223 R-DRE-446214 https://reactome.org/PathwayBrowser/#/R-DRE-446214 Synthesis of dolichyl-phosphate-glucose IEA Danio rerio 58223 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 58223 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 58223 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 58223 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 58223 R-DRE-5617037 https://reactome.org/PathwayBrowser/#/R-DRE-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Danio rerio 58223 R-DRE-5617138 https://reactome.org/PathwayBrowser/#/R-DRE-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Danio rerio 58223 R-DRE-5617143 https://reactome.org/PathwayBrowser/#/R-DRE-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Danio rerio 58223 R-DRE-5653878 https://reactome.org/PathwayBrowser/#/R-DRE-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Danio rerio 58223 R-DRE-73548 https://reactome.org/PathwayBrowser/#/R-DRE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Danio rerio 58223 R-DRE-75125 https://reactome.org/PathwayBrowser/#/R-DRE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Danio rerio 58223 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 58223 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 58223 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 58223 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 58223 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 58223 R-DRE-9033959 https://reactome.org/PathwayBrowser/#/R-DRE-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Danio rerio 58223 R-DRE-9033961 https://reactome.org/PathwayBrowser/#/R-DRE-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Danio rerio 58223 R-DRE-9034042 https://reactome.org/PathwayBrowser/#/R-DRE-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Danio rerio 58223 R-DRE-9034053 https://reactome.org/PathwayBrowser/#/R-DRE-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Danio rerio 58223 R-DRE-913675 https://reactome.org/PathwayBrowser/#/R-DRE-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Danio rerio 58223 R-DRE-914005 https://reactome.org/PathwayBrowser/#/R-DRE-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Danio rerio 58223 R-DRE-914006 https://reactome.org/PathwayBrowser/#/R-DRE-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Danio rerio 58223 R-DRE-914008 https://reactome.org/PathwayBrowser/#/R-DRE-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Danio rerio 58223 R-DRE-914010 https://reactome.org/PathwayBrowser/#/R-DRE-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Danio rerio 58223 R-DRE-914012 https://reactome.org/PathwayBrowser/#/R-DRE-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Danio rerio 58223 R-DRE-914017 https://reactome.org/PathwayBrowser/#/R-DRE-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Danio rerio 58223 R-DRE-9603989 https://reactome.org/PathwayBrowser/#/R-DRE-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Danio rerio 58223 R-DRE-9632033 https://reactome.org/PathwayBrowser/#/R-DRE-9632033 CHSY1 transfers GalNAc to chondroitin IEA Danio rerio 58223 R-DRE-9632034 https://reactome.org/PathwayBrowser/#/R-DRE-9632034 CHSY1 transfers GlcA to chondroitin IEA Danio rerio 58223 R-DRE-9638090 https://reactome.org/PathwayBrowser/#/R-DRE-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Danio rerio 58223 R-DRE-9638097 https://reactome.org/PathwayBrowser/#/R-DRE-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Danio rerio 58223 R-DRE-964768 https://reactome.org/PathwayBrowser/#/R-DRE-964768 Addition of GlcNAc to the glycan on the A arm IEA Danio rerio 58223 R-DRE-975829 https://reactome.org/PathwayBrowser/#/R-DRE-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Danio rerio 58223 R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 58223 R-DRE-9846501 https://reactome.org/PathwayBrowser/#/R-DRE-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Danio rerio 58223 R-DRE-9851347 https://reactome.org/PathwayBrowser/#/R-DRE-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Danio rerio 58223 R-GGA-158546 https://reactome.org/PathwayBrowser/#/R-GGA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Gallus gallus 58223 R-GGA-162730 https://reactome.org/PathwayBrowser/#/R-GGA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Gallus gallus 58223 R-GGA-1638104 https://reactome.org/PathwayBrowser/#/R-GGA-1638104 UGCG transfers glucose to ceramide IEA Gallus gallus 58223 R-GGA-1878002 https://reactome.org/PathwayBrowser/#/R-GGA-1878002 XYLTs transfer Xyl to core protein IEA Gallus gallus 58223 R-GGA-1889955 https://reactome.org/PathwayBrowser/#/R-GGA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Gallus gallus 58223 R-GGA-1889981 https://reactome.org/PathwayBrowser/#/R-GGA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Gallus gallus 58223 R-GGA-1964501 https://reactome.org/PathwayBrowser/#/R-GGA-1964501 Addition of galactose to Core 6 glycoprotein IEA Gallus gallus 58223 R-GGA-1964505 https://reactome.org/PathwayBrowser/#/R-GGA-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Gallus gallus 58223 R-GGA-1971482 https://reactome.org/PathwayBrowser/#/R-GGA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Gallus gallus 58223 R-GGA-1971487 https://reactome.org/PathwayBrowser/#/R-GGA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Gallus gallus 58223 R-GGA-1971491 https://reactome.org/PathwayBrowser/#/R-GGA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Gallus gallus 58223 R-GGA-2025723 https://reactome.org/PathwayBrowser/#/R-GGA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Gallus gallus 58223 R-GGA-2025724 https://reactome.org/PathwayBrowser/#/R-GGA-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Gallus gallus 58223 R-GGA-2046265 https://reactome.org/PathwayBrowser/#/R-GGA-2046265 B4GALTs transfer Gal to the keratan chain IEA Gallus gallus 58223 R-GGA-2046298 https://reactome.org/PathwayBrowser/#/R-GGA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Gallus gallus 58223 R-GGA-3322001 https://reactome.org/PathwayBrowser/#/R-GGA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Gallus gallus 58223 R-GGA-3322003 https://reactome.org/PathwayBrowser/#/R-GGA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Gallus gallus 58223 R-GGA-3322009 https://reactome.org/PathwayBrowser/#/R-GGA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Gallus gallus 58223 R-GGA-3322014 https://reactome.org/PathwayBrowser/#/R-GGA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Gallus gallus 58223 R-GGA-3322019 https://reactome.org/PathwayBrowser/#/R-GGA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Gallus gallus 58223 R-GGA-3322025 https://reactome.org/PathwayBrowser/#/R-GGA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Gallus gallus 58223 R-GGA-3322041 https://reactome.org/PathwayBrowser/#/R-GGA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Gallus gallus 58223 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 58223 R-GGA-4085021 https://reactome.org/PathwayBrowser/#/R-GGA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Gallus gallus 58223 R-GGA-417896 https://reactome.org/PathwayBrowser/#/R-GGA-417896 P2Y6 receptor can bind to UDP IEA Gallus gallus 58223 R-GGA-446207 https://reactome.org/PathwayBrowser/#/R-GGA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Gallus gallus 58223 R-GGA-446214 https://reactome.org/PathwayBrowser/#/R-GGA-446214 Synthesis of dolichyl-phosphate-glucose IEA Gallus gallus 58223 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 58223 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 58223 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 58223 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 58223 R-GGA-5617037 https://reactome.org/PathwayBrowser/#/R-GGA-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Gallus gallus 58223 R-GGA-5653878 https://reactome.org/PathwayBrowser/#/R-GGA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Gallus gallus 58223 R-GGA-5694487 https://reactome.org/PathwayBrowser/#/R-GGA-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Gallus gallus 58223 R-GGA-73548 https://reactome.org/PathwayBrowser/#/R-GGA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Gallus gallus 58223 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 58223 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 58223 R-GGA-75125 https://reactome.org/PathwayBrowser/#/R-GGA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Gallus gallus 58223 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58223 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58223 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58223 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58223 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58223 R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58223 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58223 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58223 R-GGA-8851619 https://reactome.org/PathwayBrowser/#/R-GGA-8851619 GALNT3 transfers GalNAc to FGF23 IEA Gallus gallus 58223 R-GGA-8878914 https://reactome.org/PathwayBrowser/#/R-GGA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Gallus gallus 58223 R-GGA-913675 https://reactome.org/PathwayBrowser/#/R-GGA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Gallus gallus 58223 R-GGA-914005 https://reactome.org/PathwayBrowser/#/R-GGA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Gallus gallus 58223 R-GGA-914006 https://reactome.org/PathwayBrowser/#/R-GGA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Gallus gallus 58223 R-GGA-914008 https://reactome.org/PathwayBrowser/#/R-GGA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Gallus gallus 58223 R-GGA-914010 https://reactome.org/PathwayBrowser/#/R-GGA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Gallus gallus 58223 R-GGA-914012 https://reactome.org/PathwayBrowser/#/R-GGA-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Gallus gallus 58223 R-GGA-914017 https://reactome.org/PathwayBrowser/#/R-GGA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Gallus gallus 58223 R-GGA-914018 https://reactome.org/PathwayBrowser/#/R-GGA-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Gallus gallus 58223 R-GGA-9603989 https://reactome.org/PathwayBrowser/#/R-GGA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Gallus gallus 58223 R-GGA-9632033 https://reactome.org/PathwayBrowser/#/R-GGA-9632033 CHSY1 transfers GalNAc to chondroitin IEA Gallus gallus 58223 R-GGA-9632034 https://reactome.org/PathwayBrowser/#/R-GGA-9632034 CHSY1 transfers GlcA to chondroitin IEA Gallus gallus 58223 R-GGA-964768 https://reactome.org/PathwayBrowser/#/R-GGA-964768 Addition of GlcNAc to the glycan on the A arm IEA Gallus gallus 58223 R-GGA-9756134 https://reactome.org/PathwayBrowser/#/R-GGA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Gallus gallus 58223 R-GGA-9756156 https://reactome.org/PathwayBrowser/#/R-GGA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Gallus gallus 58223 R-GGA-9756183 https://reactome.org/PathwayBrowser/#/R-GGA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Gallus gallus 58223 R-GGA-975829 https://reactome.org/PathwayBrowser/#/R-GGA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Gallus gallus 58223 R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 58223 R-GGA-9846477 https://reactome.org/PathwayBrowser/#/R-GGA-9846477 A4GALT transfers galactose to LacCer IEA Gallus gallus 58223 R-GGA-9846501 https://reactome.org/PathwayBrowser/#/R-GGA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Gallus gallus 58223 R-GGA-9851347 https://reactome.org/PathwayBrowser/#/R-GGA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Gallus gallus 58223 R-HSA-158546 https://reactome.org/PathwayBrowser/#/R-HSA-158546 UGTs glucuronate APAP to APAP-GlcA TAS Homo sapiens 58223 R-HSA-162730 https://reactome.org/PathwayBrowser/#/R-HSA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP TAS Homo sapiens 58223 R-HSA-1638104 https://reactome.org/PathwayBrowser/#/R-HSA-1638104 UGCG transfers glucose to ceramide TAS Homo sapiens 58223 R-HSA-1878002 https://reactome.org/PathwayBrowser/#/R-HSA-1878002 XYLTs transfer Xyl to core protein TAS Homo sapiens 58223 R-HSA-1889955 https://reactome.org/PathwayBrowser/#/R-HSA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker TAS Homo sapiens 58223 R-HSA-1889978 https://reactome.org/PathwayBrowser/#/R-HSA-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker TAS Homo sapiens 58223 R-HSA-1889981 https://reactome.org/PathwayBrowser/#/R-HSA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker TAS Homo sapiens 58223 R-HSA-1912352 https://reactome.org/PathwayBrowser/#/R-HSA-1912352 Galactosylation of Pre-NOTCH IEA Homo sapiens 58223 R-HSA-1912355 https://reactome.org/PathwayBrowser/#/R-HSA-1912355 Glycosylation of Pre-NOTCH by FRINGE IEA Homo sapiens 58223 R-HSA-1964501 https://reactome.org/PathwayBrowser/#/R-HSA-1964501 Addition of galactose to Core 6 glycoprotein TAS Homo sapiens 58223 R-HSA-1964505 https://reactome.org/PathwayBrowser/#/R-HSA-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) TAS Homo sapiens 58223 R-HSA-1971482 https://reactome.org/PathwayBrowser/#/R-HSA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin TAS Homo sapiens 58223 R-HSA-1971487 https://reactome.org/PathwayBrowser/#/R-HSA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin TAS Homo sapiens 58223 R-HSA-1971491 https://reactome.org/PathwayBrowser/#/R-HSA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin TAS Homo sapiens 58223 R-HSA-2022851 https://reactome.org/PathwayBrowser/#/R-HSA-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain TAS Homo sapiens 58223 R-HSA-2022856 https://reactome.org/PathwayBrowser/#/R-HSA-2022856 EXT1:EXT2 transfers GlcNAc to heparan TAS Homo sapiens 58223 R-HSA-2022919 https://reactome.org/PathwayBrowser/#/R-HSA-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue TAS Homo sapiens 58223 R-HSA-2025723 https://reactome.org/PathwayBrowser/#/R-HSA-2025723 B4GALTs transfer Gal to the N-glycan precursor TAS Homo sapiens 58223 R-HSA-2025724 https://reactome.org/PathwayBrowser/#/R-HSA-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG TAS Homo sapiens 58223 R-HSA-2046265 https://reactome.org/PathwayBrowser/#/R-HSA-2046265 B4GALTs transfer Gal to the keratan chain TAS Homo sapiens 58223 R-HSA-2046298 https://reactome.org/PathwayBrowser/#/R-HSA-2046298 B4GALTs transfer Gal to a branch of keratan TAS Homo sapiens 58223 R-HSA-2076392 https://reactome.org/PathwayBrowser/#/R-HSA-2076392 EXT1:EXT2 transfers GlcA to heparan TAS Homo sapiens 58223 R-HSA-2162099 https://reactome.org/PathwayBrowser/#/R-HSA-2162099 abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP TAS Homo sapiens 58223 R-HSA-3322001 https://reactome.org/PathwayBrowser/#/R-HSA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 TAS Homo sapiens 58223 R-HSA-3322003 https://reactome.org/PathwayBrowser/#/R-HSA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b TAS Homo sapiens 58223 R-HSA-3322009 https://reactome.org/PathwayBrowser/#/R-HSA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 TAS Homo sapiens 58223 R-HSA-3322014 https://reactome.org/PathwayBrowser/#/R-HSA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a TAS Homo sapiens 58223 R-HSA-3322019 https://reactome.org/PathwayBrowser/#/R-HSA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b TAS Homo sapiens 58223 R-HSA-3322025 https://reactome.org/PathwayBrowser/#/R-HSA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a TAS Homo sapiens 58223 R-HSA-3322041 https://reactome.org/PathwayBrowser/#/R-HSA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 TAS Homo sapiens 58223 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 58223 R-HSA-4085021 https://reactome.org/PathwayBrowser/#/R-HSA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP TAS Homo sapiens 58223 R-HSA-417896 https://reactome.org/PathwayBrowser/#/R-HSA-417896 P2Y6 receptor can bind to UDP TAS Homo sapiens 58223 R-HSA-418918 https://reactome.org/PathwayBrowser/#/R-HSA-418918 The UDP/CysLT (P2Y17) receptor can bind UTP TAS Homo sapiens 58223 R-HSA-446207 https://reactome.org/PathwayBrowser/#/R-HSA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP TAS Homo sapiens 58223 R-HSA-446214 https://reactome.org/PathwayBrowser/#/R-HSA-446214 Synthesis of dolichyl-phosphate-glucose TAS Homo sapiens 58223 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 58223 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 58223 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 58223 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 58223 R-HSA-5617037 https://reactome.org/PathwayBrowser/#/R-HSA-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 TAS Homo sapiens 58223 R-HSA-5617138 https://reactome.org/PathwayBrowser/#/R-HSA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA TAS Homo sapiens 58223 R-HSA-5617143 https://reactome.org/PathwayBrowser/#/R-HSA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA TAS Homo sapiens 58223 R-HSA-5653878 https://reactome.org/PathwayBrowser/#/R-HSA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac TAS Homo sapiens 58223 R-HSA-5694487 https://reactome.org/PathwayBrowser/#/R-HSA-5694487 A4GNT transfers GlcNAc to core 2 mucins TAS Homo sapiens 58223 R-HSA-73548 https://reactome.org/PathwayBrowser/#/R-HSA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) TAS Homo sapiens 58223 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 58223 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 58223 R-HSA-75125 https://reactome.org/PathwayBrowser/#/R-HSA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) TAS Homo sapiens 58223 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58223 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58223 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58223 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58223 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58223 R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58223 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58223 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58223 R-HSA-8851619 https://reactome.org/PathwayBrowser/#/R-HSA-8851619 GALNT3 transfers GalNAc to FGF23 TAS Homo sapiens 58223 R-HSA-8855954 https://reactome.org/PathwayBrowser/#/R-HSA-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD TAS Homo sapiens 58223 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 58223 R-HSA-8878914 https://reactome.org/PathwayBrowser/#/R-HSA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer TAS Homo sapiens 58223 R-HSA-9033959 https://reactome.org/PathwayBrowser/#/R-HSA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC TAS Homo sapiens 58223 R-HSA-9033961 https://reactome.org/PathwayBrowser/#/R-HSA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC TAS Homo sapiens 58223 R-HSA-9034042 https://reactome.org/PathwayBrowser/#/R-HSA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec TAS Homo sapiens 58223 R-HSA-9034053 https://reactome.org/PathwayBrowser/#/R-HSA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen TAS Homo sapiens 58223 R-HSA-913675 https://reactome.org/PathwayBrowser/#/R-HSA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens TAS Homo sapiens 58223 R-HSA-914005 https://reactome.org/PathwayBrowser/#/R-HSA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein TAS Homo sapiens 58223 R-HSA-914006 https://reactome.org/PathwayBrowser/#/R-HSA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein TAS Homo sapiens 58223 R-HSA-914008 https://reactome.org/PathwayBrowser/#/R-HSA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein TAS Homo sapiens 58223 R-HSA-914010 https://reactome.org/PathwayBrowser/#/R-HSA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein TAS Homo sapiens 58223 R-HSA-914012 https://reactome.org/PathwayBrowser/#/R-HSA-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins TAS Homo sapiens 58223 R-HSA-914017 https://reactome.org/PathwayBrowser/#/R-HSA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein TAS Homo sapiens 58223 R-HSA-914018 https://reactome.org/PathwayBrowser/#/R-HSA-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein TAS Homo sapiens 58223 R-HSA-9603989 https://reactome.org/PathwayBrowser/#/R-HSA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain TAS Homo sapiens 58223 R-HSA-9605700 https://reactome.org/PathwayBrowser/#/R-HSA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda TAS Homo sapiens 58223 R-HSA-9632033 https://reactome.org/PathwayBrowser/#/R-HSA-9632033 CHSY1 transfers GalNAc to chondroitin TAS Homo sapiens 58223 R-HSA-9632034 https://reactome.org/PathwayBrowser/#/R-HSA-9632034 CHSY1 transfers GlcA to chondroitin TAS Homo sapiens 58223 R-HSA-9638064 https://reactome.org/PathwayBrowser/#/R-HSA-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker TAS Homo sapiens 58223 R-HSA-9638090 https://reactome.org/PathwayBrowser/#/R-HSA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA TAS Homo sapiens 58223 R-HSA-9638097 https://reactome.org/PathwayBrowser/#/R-HSA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA TAS Homo sapiens 58223 R-HSA-964768 https://reactome.org/PathwayBrowser/#/R-HSA-964768 Addition of GlcNAc to the glycan on the A arm TAS Homo sapiens 58223 R-HSA-9687828 https://reactome.org/PathwayBrowser/#/R-HSA-9687828 O-GlcNAcylation of RIPK3 (TLR4 signaling) TAS Homo sapiens 58223 R-HSA-9756134 https://reactome.org/PathwayBrowser/#/R-HSA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL TAS Homo sapiens 58223 R-HSA-9756156 https://reactome.org/PathwayBrowser/#/R-HSA-9756156 UGT1A3 lactonizes ATV to ATVL TAS Homo sapiens 58223 R-HSA-9756183 https://reactome.org/PathwayBrowser/#/R-HSA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL TAS Homo sapiens 58223 R-HSA-975829 https://reactome.org/PathwayBrowser/#/R-HSA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 TAS Homo sapiens 58223 R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 58223 R-HSA-9845516 https://reactome.org/PathwayBrowser/#/R-HSA-9845516 B3GALT4 transfers Gal to gangliosides TAS Homo sapiens 58223 R-HSA-9846477 https://reactome.org/PathwayBrowser/#/R-HSA-9846477 A4GALT transfers galactose to LacCer TAS Homo sapiens 58223 R-HSA-9846501 https://reactome.org/PathwayBrowser/#/R-HSA-9846501 B3GNT5 transfers GlcNAc to LacCer TAS Homo sapiens 58223 R-HSA-9851347 https://reactome.org/PathwayBrowser/#/R-HSA-9851347 B4GALT5/6 transfer Gal to GlcCer TAS Homo sapiens 58223 R-MMU-158546 https://reactome.org/PathwayBrowser/#/R-MMU-158546 UGTs glucuronate APAP to APAP-GlcA IEA Mus musculus 58223 R-MMU-162730 https://reactome.org/PathwayBrowser/#/R-MMU-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Mus musculus 58223 R-MMU-1638104 https://reactome.org/PathwayBrowser/#/R-MMU-1638104 UGCG transfers glucose to ceramide IEA Mus musculus 58223 R-MMU-1878002 https://reactome.org/PathwayBrowser/#/R-MMU-1878002 XYLTs transfer Xyl to core protein IEA Mus musculus 58223 R-MMU-1889955 https://reactome.org/PathwayBrowser/#/R-MMU-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Mus musculus 58223 R-MMU-1889978 https://reactome.org/PathwayBrowser/#/R-MMU-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Mus musculus 58223 R-MMU-1889981 https://reactome.org/PathwayBrowser/#/R-MMU-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Mus musculus 58223 R-MMU-1964501 https://reactome.org/PathwayBrowser/#/R-MMU-1964501 Addition of galactose to Core 6 glycoprotein IEA Mus musculus 58223 R-MMU-1964505 https://reactome.org/PathwayBrowser/#/R-MMU-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Mus musculus 58223 R-MMU-1971482 https://reactome.org/PathwayBrowser/#/R-MMU-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Mus musculus 58223 R-MMU-1971487 https://reactome.org/PathwayBrowser/#/R-MMU-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Mus musculus 58223 R-MMU-1971491 https://reactome.org/PathwayBrowser/#/R-MMU-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Mus musculus 58223 R-MMU-2022851 https://reactome.org/PathwayBrowser/#/R-MMU-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Mus musculus 58223 R-MMU-2022856 https://reactome.org/PathwayBrowser/#/R-MMU-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Mus musculus 58223 R-MMU-2022919 https://reactome.org/PathwayBrowser/#/R-MMU-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Mus musculus 58223 R-MMU-2023158 https://reactome.org/PathwayBrowser/#/R-MMU-2023158 Glycosylation of Pre-Notch by Fringe TAS Mus musculus 58223 R-MMU-2025723 https://reactome.org/PathwayBrowser/#/R-MMU-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Mus musculus 58223 R-MMU-2025724 https://reactome.org/PathwayBrowser/#/R-MMU-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Mus musculus 58223 R-MMU-2046265 https://reactome.org/PathwayBrowser/#/R-MMU-2046265 B4GALTs transfer Gal to the keratan chain IEA Mus musculus 58223 R-MMU-2046298 https://reactome.org/PathwayBrowser/#/R-MMU-2046298 B4GALTs transfer Gal to a branch of keratan IEA Mus musculus 58223 R-MMU-2076392 https://reactome.org/PathwayBrowser/#/R-MMU-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Mus musculus 58223 R-MMU-3322001 https://reactome.org/PathwayBrowser/#/R-MMU-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Mus musculus 58223 R-MMU-3322003 https://reactome.org/PathwayBrowser/#/R-MMU-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Mus musculus 58223 R-MMU-3322025 https://reactome.org/PathwayBrowser/#/R-MMU-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Mus musculus 58223 R-MMU-3322041 https://reactome.org/PathwayBrowser/#/R-MMU-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Mus musculus 58223 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 58223 R-MMU-4085021 https://reactome.org/PathwayBrowser/#/R-MMU-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Mus musculus 58223 R-MMU-417896 https://reactome.org/PathwayBrowser/#/R-MMU-417896 P2Y6 receptor can bind to UDP IEA Mus musculus 58223 R-MMU-418918 https://reactome.org/PathwayBrowser/#/R-MMU-418918 The UDP/CysLT (P2Y17) receptor can bind UTP IEA Mus musculus 58223 R-MMU-446207 https://reactome.org/PathwayBrowser/#/R-MMU-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Mus musculus 58223 R-MMU-446214 https://reactome.org/PathwayBrowser/#/R-MMU-446214 Synthesis of dolichyl-phosphate-glucose IEA Mus musculus 58223 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 58223 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 58223 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 58223 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 58223 R-MMU-5617037 https://reactome.org/PathwayBrowser/#/R-MMU-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Mus musculus 58223 R-MMU-5617138 https://reactome.org/PathwayBrowser/#/R-MMU-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Mus musculus 58223 R-MMU-5617143 https://reactome.org/PathwayBrowser/#/R-MMU-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Mus musculus 58223 R-MMU-5653878 https://reactome.org/PathwayBrowser/#/R-MMU-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Mus musculus 58223 R-MMU-5694487 https://reactome.org/PathwayBrowser/#/R-MMU-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Mus musculus 58223 R-MMU-73548 https://reactome.org/PathwayBrowser/#/R-MMU-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Mus musculus 58223 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 58223 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 58223 R-MMU-75125 https://reactome.org/PathwayBrowser/#/R-MMU-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Mus musculus 58223 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 58223 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 58223 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 58223 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 58223 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 58223 R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 58223 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 58223 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 58223 R-MMU-8851619 https://reactome.org/PathwayBrowser/#/R-MMU-8851619 GALNT3 transfers GalNAc to FGF23 IEA Mus musculus 58223 R-MMU-8855954 https://reactome.org/PathwayBrowser/#/R-MMU-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Mus musculus 58223 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 58223 R-MMU-8878914 https://reactome.org/PathwayBrowser/#/R-MMU-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Mus musculus 58223 R-MMU-9033959 https://reactome.org/PathwayBrowser/#/R-MMU-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Mus musculus 58223 R-MMU-9033961 https://reactome.org/PathwayBrowser/#/R-MMU-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Mus musculus 58223 R-MMU-9034042 https://reactome.org/PathwayBrowser/#/R-MMU-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Mus musculus 58223 R-MMU-9034053 https://reactome.org/PathwayBrowser/#/R-MMU-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Mus musculus 58223 R-MMU-913675 https://reactome.org/PathwayBrowser/#/R-MMU-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Mus musculus 58223 R-MMU-914005 https://reactome.org/PathwayBrowser/#/R-MMU-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Mus musculus 58223 R-MMU-914006 https://reactome.org/PathwayBrowser/#/R-MMU-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Mus musculus 58223 R-MMU-914008 https://reactome.org/PathwayBrowser/#/R-MMU-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Mus musculus 58223 R-MMU-914010 https://reactome.org/PathwayBrowser/#/R-MMU-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Mus musculus 58223 R-MMU-914012 https://reactome.org/PathwayBrowser/#/R-MMU-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Mus musculus 58223 R-MMU-914017 https://reactome.org/PathwayBrowser/#/R-MMU-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Mus musculus 58223 R-MMU-914018 https://reactome.org/PathwayBrowser/#/R-MMU-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Mus musculus 58223 R-MMU-9603989 https://reactome.org/PathwayBrowser/#/R-MMU-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Mus musculus 58223 R-MMU-9605700 https://reactome.org/PathwayBrowser/#/R-MMU-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Mus musculus 58223 R-MMU-9632033 https://reactome.org/PathwayBrowser/#/R-MMU-9632033 CHSY1 transfers GalNAc to chondroitin IEA Mus musculus 58223 R-MMU-9632034 https://reactome.org/PathwayBrowser/#/R-MMU-9632034 CHSY1 transfers GlcA to chondroitin IEA Mus musculus 58223 R-MMU-9638064 https://reactome.org/PathwayBrowser/#/R-MMU-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Mus musculus 58223 R-MMU-9638090 https://reactome.org/PathwayBrowser/#/R-MMU-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Mus musculus 58223 R-MMU-9638097 https://reactome.org/PathwayBrowser/#/R-MMU-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Mus musculus 58223 R-MMU-964768 https://reactome.org/PathwayBrowser/#/R-MMU-964768 Addition of GlcNAc to the glycan on the A arm IEA Mus musculus 58223 R-MMU-9687828 https://reactome.org/PathwayBrowser/#/R-MMU-9687828 O-GlcNAcylation of RIPK3 (TLR4 signaling) IEA Mus musculus 58223 R-MMU-9756134 https://reactome.org/PathwayBrowser/#/R-MMU-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Mus musculus 58223 R-MMU-9756156 https://reactome.org/PathwayBrowser/#/R-MMU-9756156 UGT1A3 lactonizes ATV to ATVL IEA Mus musculus 58223 R-MMU-9756183 https://reactome.org/PathwayBrowser/#/R-MMU-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Mus musculus 58223 R-MMU-975829 https://reactome.org/PathwayBrowser/#/R-MMU-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Mus musculus 58223 R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 58223 R-MMU-9845516 https://reactome.org/PathwayBrowser/#/R-MMU-9845516 B3GALT4 transfers Gal to gangliosides IEA Mus musculus 58223 R-MMU-9846477 https://reactome.org/PathwayBrowser/#/R-MMU-9846477 A4GALT transfers galactose to LacCer IEA Mus musculus 58223 R-MMU-9846501 https://reactome.org/PathwayBrowser/#/R-MMU-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Mus musculus 58223 R-MMU-9851347 https://reactome.org/PathwayBrowser/#/R-MMU-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Mus musculus 58223 R-MTU-868622 https://reactome.org/PathwayBrowser/#/R-MTU-868622 Glucose is transferred from UDP-glucose onto glucose-6-phosphate TAS Mycobacterium tuberculosis 58223 R-MTU-879298 https://reactome.org/PathwayBrowser/#/R-MTU-879298 acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate TAS Mycobacterium tuberculosis 58223 R-PFA-446207 https://reactome.org/PathwayBrowser/#/R-PFA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Plasmodium falciparum 58223 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 58223 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 58223 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 58223 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 58223 R-PFA-73548 https://reactome.org/PathwayBrowser/#/R-PFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Plasmodium falciparum 58223 R-PFA-75125 https://reactome.org/PathwayBrowser/#/R-PFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Plasmodium falciparum 58223 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 58223 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58223 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58223 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 58223 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58223 R-PFA-914005 https://reactome.org/PathwayBrowser/#/R-PFA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Plasmodium falciparum 58223 R-PFA-914006 https://reactome.org/PathwayBrowser/#/R-PFA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Plasmodium falciparum 58223 R-PFA-914008 https://reactome.org/PathwayBrowser/#/R-PFA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Plasmodium falciparum 58223 R-PFA-914017 https://reactome.org/PathwayBrowser/#/R-PFA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Plasmodium falciparum 58223 R-RNO-158546 https://reactome.org/PathwayBrowser/#/R-RNO-158546 UGTs glucuronate APAP to APAP-GlcA IEA Rattus norvegicus 58223 R-RNO-162730 https://reactome.org/PathwayBrowser/#/R-RNO-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Rattus norvegicus 58223 R-RNO-1638104 https://reactome.org/PathwayBrowser/#/R-RNO-1638104 UGCG transfers glucose to ceramide IEA Rattus norvegicus 58223 R-RNO-1878002 https://reactome.org/PathwayBrowser/#/R-RNO-1878002 XYLTs transfer Xyl to core protein IEA Rattus norvegicus 58223 R-RNO-1889955 https://reactome.org/PathwayBrowser/#/R-RNO-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Rattus norvegicus 58223 R-RNO-1889978 https://reactome.org/PathwayBrowser/#/R-RNO-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Rattus norvegicus 58223 R-RNO-1889981 https://reactome.org/PathwayBrowser/#/R-RNO-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Rattus norvegicus 58223 R-RNO-1964501 https://reactome.org/PathwayBrowser/#/R-RNO-1964501 Addition of galactose to Core 6 glycoprotein IEA Rattus norvegicus 58223 R-RNO-1964505 https://reactome.org/PathwayBrowser/#/R-RNO-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Rattus norvegicus 58223 R-RNO-1971482 https://reactome.org/PathwayBrowser/#/R-RNO-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Rattus norvegicus 58223 R-RNO-1971487 https://reactome.org/PathwayBrowser/#/R-RNO-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Rattus norvegicus 58223 R-RNO-1971491 https://reactome.org/PathwayBrowser/#/R-RNO-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Rattus norvegicus 58223 R-RNO-2022851 https://reactome.org/PathwayBrowser/#/R-RNO-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Rattus norvegicus 58223 R-RNO-2022856 https://reactome.org/PathwayBrowser/#/R-RNO-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Rattus norvegicus 58223 R-RNO-2022919 https://reactome.org/PathwayBrowser/#/R-RNO-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Rattus norvegicus 58223 R-RNO-2025723 https://reactome.org/PathwayBrowser/#/R-RNO-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Rattus norvegicus 58223 R-RNO-2025724 https://reactome.org/PathwayBrowser/#/R-RNO-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Rattus norvegicus 58223 R-RNO-2046265 https://reactome.org/PathwayBrowser/#/R-RNO-2046265 B4GALTs transfer Gal to the keratan chain IEA Rattus norvegicus 58223 R-RNO-2046298 https://reactome.org/PathwayBrowser/#/R-RNO-2046298 B4GALTs transfer Gal to a branch of keratan IEA Rattus norvegicus 58223 R-RNO-2076392 https://reactome.org/PathwayBrowser/#/R-RNO-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Rattus norvegicus 58223 R-RNO-3322001 https://reactome.org/PathwayBrowser/#/R-RNO-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Rattus norvegicus 58223 R-RNO-3322003 https://reactome.org/PathwayBrowser/#/R-RNO-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Rattus norvegicus 58223 R-RNO-3322025 https://reactome.org/PathwayBrowser/#/R-RNO-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Rattus norvegicus 58223 R-RNO-3322041 https://reactome.org/PathwayBrowser/#/R-RNO-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Rattus norvegicus 58223 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 58223 R-RNO-4085021 https://reactome.org/PathwayBrowser/#/R-RNO-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Rattus norvegicus 58223 R-RNO-417896 https://reactome.org/PathwayBrowser/#/R-RNO-417896 P2Y6 receptor can bind to UDP IEA Rattus norvegicus 58223 R-RNO-418918 https://reactome.org/PathwayBrowser/#/R-RNO-418918 The UDP/CysLT (P2Y17) receptor can bind UTP IEA Rattus norvegicus 58223 R-RNO-446207 https://reactome.org/PathwayBrowser/#/R-RNO-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Rattus norvegicus 58223 R-RNO-446214 https://reactome.org/PathwayBrowser/#/R-RNO-446214 Synthesis of dolichyl-phosphate-glucose IEA Rattus norvegicus 58223 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 58223 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 58223 R-RNO-5617037 https://reactome.org/PathwayBrowser/#/R-RNO-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Rattus norvegicus 58223 R-RNO-5617138 https://reactome.org/PathwayBrowser/#/R-RNO-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Rattus norvegicus 58223 R-RNO-5617143 https://reactome.org/PathwayBrowser/#/R-RNO-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Rattus norvegicus 58223 R-RNO-5694487 https://reactome.org/PathwayBrowser/#/R-RNO-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Rattus norvegicus 58223 R-RNO-73548 https://reactome.org/PathwayBrowser/#/R-RNO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Rattus norvegicus 58223 R-RNO-75125 https://reactome.org/PathwayBrowser/#/R-RNO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Rattus norvegicus 58223 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58223 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58223 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58223 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58223 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58223 R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58223 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58223 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58223 R-RNO-8851619 https://reactome.org/PathwayBrowser/#/R-RNO-8851619 GALNT3 transfers GalNAc to FGF23 IEA Rattus norvegicus 58223 R-RNO-8855954 https://reactome.org/PathwayBrowser/#/R-RNO-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Rattus norvegicus 58223 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 58223 R-RNO-8878914 https://reactome.org/PathwayBrowser/#/R-RNO-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Rattus norvegicus 58223 R-RNO-9033959 https://reactome.org/PathwayBrowser/#/R-RNO-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Rattus norvegicus 58223 R-RNO-9033961 https://reactome.org/PathwayBrowser/#/R-RNO-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Rattus norvegicus 58223 R-RNO-9034042 https://reactome.org/PathwayBrowser/#/R-RNO-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Rattus norvegicus 58223 R-RNO-9034053 https://reactome.org/PathwayBrowser/#/R-RNO-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Rattus norvegicus 58223 R-RNO-913675 https://reactome.org/PathwayBrowser/#/R-RNO-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Rattus norvegicus 58223 R-RNO-914005 https://reactome.org/PathwayBrowser/#/R-RNO-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Rattus norvegicus 58223 R-RNO-914006 https://reactome.org/PathwayBrowser/#/R-RNO-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Rattus norvegicus 58223 R-RNO-914008 https://reactome.org/PathwayBrowser/#/R-RNO-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Rattus norvegicus 58223 R-RNO-914010 https://reactome.org/PathwayBrowser/#/R-RNO-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Rattus norvegicus 58223 R-RNO-914012 https://reactome.org/PathwayBrowser/#/R-RNO-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Rattus norvegicus 58223 R-RNO-914017 https://reactome.org/PathwayBrowser/#/R-RNO-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Rattus norvegicus 58223 R-RNO-914018 https://reactome.org/PathwayBrowser/#/R-RNO-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Rattus norvegicus 58223 R-RNO-9603989 https://reactome.org/PathwayBrowser/#/R-RNO-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Rattus norvegicus 58223 R-RNO-9605700 https://reactome.org/PathwayBrowser/#/R-RNO-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Rattus norvegicus 58223 R-RNO-9632033 https://reactome.org/PathwayBrowser/#/R-RNO-9632033 CHSY1 transfers GalNAc to chondroitin IEA Rattus norvegicus 58223 R-RNO-9632034 https://reactome.org/PathwayBrowser/#/R-RNO-9632034 CHSY1 transfers GlcA to chondroitin IEA Rattus norvegicus 58223 R-RNO-9638090 https://reactome.org/PathwayBrowser/#/R-RNO-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Rattus norvegicus 58223 R-RNO-9638097 https://reactome.org/PathwayBrowser/#/R-RNO-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Rattus norvegicus 58223 R-RNO-964768 https://reactome.org/PathwayBrowser/#/R-RNO-964768 Addition of GlcNAc to the glycan on the A arm IEA Rattus norvegicus 58223 R-RNO-9687828 https://reactome.org/PathwayBrowser/#/R-RNO-9687828 O-GlcNAcylation of RIPK3 (TLR4 signaling) IEA Rattus norvegicus 58223 R-RNO-9756134 https://reactome.org/PathwayBrowser/#/R-RNO-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Rattus norvegicus 58223 R-RNO-9756156 https://reactome.org/PathwayBrowser/#/R-RNO-9756156 UGT1A3 lactonizes ATV to ATVL IEA Rattus norvegicus 58223 R-RNO-9756183 https://reactome.org/PathwayBrowser/#/R-RNO-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Rattus norvegicus 58223 R-RNO-975829 https://reactome.org/PathwayBrowser/#/R-RNO-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Rattus norvegicus 58223 R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 58223 R-RNO-9845516 https://reactome.org/PathwayBrowser/#/R-RNO-9845516 B3GALT4 transfers Gal to gangliosides IEA Rattus norvegicus 58223 R-RNO-9846477 https://reactome.org/PathwayBrowser/#/R-RNO-9846477 A4GALT transfers galactose to LacCer IEA Rattus norvegicus 58223 R-RNO-9846501 https://reactome.org/PathwayBrowser/#/R-RNO-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Rattus norvegicus 58223 R-RNO-9851347 https://reactome.org/PathwayBrowser/#/R-RNO-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Rattus norvegicus 58223 R-SCE-3322001 https://reactome.org/PathwayBrowser/#/R-SCE-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Saccharomyces cerevisiae 58223 R-SCE-3322003 https://reactome.org/PathwayBrowser/#/R-SCE-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Saccharomyces cerevisiae 58223 R-SCE-3322009 https://reactome.org/PathwayBrowser/#/R-SCE-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Saccharomyces cerevisiae 58223 R-SCE-3322014 https://reactome.org/PathwayBrowser/#/R-SCE-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Saccharomyces cerevisiae 58223 R-SCE-3322019 https://reactome.org/PathwayBrowser/#/R-SCE-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Saccharomyces cerevisiae 58223 R-SCE-3322025 https://reactome.org/PathwayBrowser/#/R-SCE-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Saccharomyces cerevisiae 58223 R-SCE-3322041 https://reactome.org/PathwayBrowser/#/R-SCE-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Saccharomyces cerevisiae 58223 R-SCE-446214 https://reactome.org/PathwayBrowser/#/R-SCE-446214 Synthesis of dolichyl-phosphate-glucose IEA Saccharomyces cerevisiae 58223 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 58223 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 58223 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 58223 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 58223 R-SCE-73548 https://reactome.org/PathwayBrowser/#/R-SCE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Saccharomyces cerevisiae 58223 R-SCE-75125 https://reactome.org/PathwayBrowser/#/R-SCE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Saccharomyces cerevisiae 58223 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58223 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 58223 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58223 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58223 R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 58223 R-SPO-446207 https://reactome.org/PathwayBrowser/#/R-SPO-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Schizosaccharomyces pombe 58223 R-SPO-446214 https://reactome.org/PathwayBrowser/#/R-SPO-446214 Synthesis of dolichyl-phosphate-glucose IEA Schizosaccharomyces pombe 58223 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 58223 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 58223 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 58223 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 58223 R-SPO-73548 https://reactome.org/PathwayBrowser/#/R-SPO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Schizosaccharomyces pombe 58223 R-SPO-75125 https://reactome.org/PathwayBrowser/#/R-SPO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Schizosaccharomyces pombe 58223 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58223 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 58223 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58223 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58223 R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 58223 R-SSC-158546 https://reactome.org/PathwayBrowser/#/R-SSC-158546 UGTs glucuronate APAP to APAP-GlcA IEA Sus scrofa 58223 R-SSC-162730 https://reactome.org/PathwayBrowser/#/R-SSC-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Sus scrofa 58223 R-SSC-1638104 https://reactome.org/PathwayBrowser/#/R-SSC-1638104 UGCG transfers glucose to ceramide IEA Sus scrofa 58223 R-SSC-1878002 https://reactome.org/PathwayBrowser/#/R-SSC-1878002 XYLTs transfer Xyl to core protein IEA Sus scrofa 58223 R-SSC-1889955 https://reactome.org/PathwayBrowser/#/R-SSC-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Sus scrofa 58223 R-SSC-1889978 https://reactome.org/PathwayBrowser/#/R-SSC-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Sus scrofa 58223 R-SSC-1889981 https://reactome.org/PathwayBrowser/#/R-SSC-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Sus scrofa 58223 R-SSC-1964501 https://reactome.org/PathwayBrowser/#/R-SSC-1964501 Addition of galactose to Core 6 glycoprotein IEA Sus scrofa 58223 R-SSC-1964505 https://reactome.org/PathwayBrowser/#/R-SSC-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Sus scrofa 58223 R-SSC-1971482 https://reactome.org/PathwayBrowser/#/R-SSC-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Sus scrofa 58223 R-SSC-1971487 https://reactome.org/PathwayBrowser/#/R-SSC-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Sus scrofa 58223 R-SSC-1971491 https://reactome.org/PathwayBrowser/#/R-SSC-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Sus scrofa 58223 R-SSC-2022851 https://reactome.org/PathwayBrowser/#/R-SSC-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Sus scrofa 58223 R-SSC-2022856 https://reactome.org/PathwayBrowser/#/R-SSC-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Sus scrofa 58223 R-SSC-2022919 https://reactome.org/PathwayBrowser/#/R-SSC-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Sus scrofa 58223 R-SSC-2025723 https://reactome.org/PathwayBrowser/#/R-SSC-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Sus scrofa 58223 R-SSC-2025724 https://reactome.org/PathwayBrowser/#/R-SSC-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Sus scrofa 58223 R-SSC-2046265 https://reactome.org/PathwayBrowser/#/R-SSC-2046265 B4GALTs transfer Gal to the keratan chain IEA Sus scrofa 58223 R-SSC-2046298 https://reactome.org/PathwayBrowser/#/R-SSC-2046298 B4GALTs transfer Gal to a branch of keratan IEA Sus scrofa 58223 R-SSC-2076392 https://reactome.org/PathwayBrowser/#/R-SSC-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Sus scrofa 58223 R-SSC-3322001 https://reactome.org/PathwayBrowser/#/R-SSC-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Sus scrofa 58223 R-SSC-3322003 https://reactome.org/PathwayBrowser/#/R-SSC-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Sus scrofa 58223 R-SSC-3322009 https://reactome.org/PathwayBrowser/#/R-SSC-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Sus scrofa 58223 R-SSC-3322014 https://reactome.org/PathwayBrowser/#/R-SSC-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Sus scrofa 58223 R-SSC-3322019 https://reactome.org/PathwayBrowser/#/R-SSC-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Sus scrofa 58223 R-SSC-3322025 https://reactome.org/PathwayBrowser/#/R-SSC-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Sus scrofa 58223 R-SSC-3322041 https://reactome.org/PathwayBrowser/#/R-SSC-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Sus scrofa 58223 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 58223 R-SSC-4085021 https://reactome.org/PathwayBrowser/#/R-SSC-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Sus scrofa 58223 R-SSC-417896 https://reactome.org/PathwayBrowser/#/R-SSC-417896 P2Y6 receptor can bind to UDP IEA Sus scrofa 58223 R-SSC-418918 https://reactome.org/PathwayBrowser/#/R-SSC-418918 The UDP/CysLT (P2Y17) receptor can bind UTP IEA Sus scrofa 58223 R-SSC-446207 https://reactome.org/PathwayBrowser/#/R-SSC-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Sus scrofa 58223 R-SSC-446214 https://reactome.org/PathwayBrowser/#/R-SSC-446214 Synthesis of dolichyl-phosphate-glucose IEA Sus scrofa 58223 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 58223 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 58223 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 58223 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 58223 R-SSC-5617037 https://reactome.org/PathwayBrowser/#/R-SSC-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Sus scrofa 58223 R-SSC-5617138 https://reactome.org/PathwayBrowser/#/R-SSC-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Sus scrofa 58223 R-SSC-5617143 https://reactome.org/PathwayBrowser/#/R-SSC-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Sus scrofa 58223 R-SSC-5653878 https://reactome.org/PathwayBrowser/#/R-SSC-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Sus scrofa 58223 R-SSC-5694487 https://reactome.org/PathwayBrowser/#/R-SSC-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Sus scrofa 58223 R-SSC-73548 https://reactome.org/PathwayBrowser/#/R-SSC-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Sus scrofa 58223 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 58223 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 58223 R-SSC-75125 https://reactome.org/PathwayBrowser/#/R-SSC-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Sus scrofa 58223 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58223 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58223 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58223 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58223 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58223 R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58223 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58223 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58223 R-SSC-8851619 https://reactome.org/PathwayBrowser/#/R-SSC-8851619 GALNT3 transfers GalNAc to FGF23 IEA Sus scrofa 58223 R-SSC-8855954 https://reactome.org/PathwayBrowser/#/R-SSC-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Sus scrofa 58223 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 58223 R-SSC-8878914 https://reactome.org/PathwayBrowser/#/R-SSC-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Sus scrofa 58223 R-SSC-913675 https://reactome.org/PathwayBrowser/#/R-SSC-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Sus scrofa 58223 R-SSC-914005 https://reactome.org/PathwayBrowser/#/R-SSC-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Sus scrofa 58223 R-SSC-914006 https://reactome.org/PathwayBrowser/#/R-SSC-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Sus scrofa 58223 R-SSC-914008 https://reactome.org/PathwayBrowser/#/R-SSC-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Sus scrofa 58223 R-SSC-914010 https://reactome.org/PathwayBrowser/#/R-SSC-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Sus scrofa 58223 R-SSC-914012 https://reactome.org/PathwayBrowser/#/R-SSC-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Sus scrofa 58223 R-SSC-914017 https://reactome.org/PathwayBrowser/#/R-SSC-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Sus scrofa 58223 R-SSC-914018 https://reactome.org/PathwayBrowser/#/R-SSC-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Sus scrofa 58223 R-SSC-9603989 https://reactome.org/PathwayBrowser/#/R-SSC-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Sus scrofa 58223 R-SSC-9605700 https://reactome.org/PathwayBrowser/#/R-SSC-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Sus scrofa 58223 R-SSC-9632033 https://reactome.org/PathwayBrowser/#/R-SSC-9632033 CHSY1 transfers GalNAc to chondroitin IEA Sus scrofa 58223 R-SSC-9632034 https://reactome.org/PathwayBrowser/#/R-SSC-9632034 CHSY1 transfers GlcA to chondroitin IEA Sus scrofa 58223 R-SSC-9638064 https://reactome.org/PathwayBrowser/#/R-SSC-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Sus scrofa 58223 R-SSC-9638090 https://reactome.org/PathwayBrowser/#/R-SSC-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Sus scrofa 58223 R-SSC-9638097 https://reactome.org/PathwayBrowser/#/R-SSC-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Sus scrofa 58223 R-SSC-964768 https://reactome.org/PathwayBrowser/#/R-SSC-964768 Addition of GlcNAc to the glycan on the A arm IEA Sus scrofa 58223 R-SSC-9756134 https://reactome.org/PathwayBrowser/#/R-SSC-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Sus scrofa 58223 R-SSC-9756156 https://reactome.org/PathwayBrowser/#/R-SSC-9756156 UGT1A3 lactonizes ATV to ATVL IEA Sus scrofa 58223 R-SSC-9756183 https://reactome.org/PathwayBrowser/#/R-SSC-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Sus scrofa 58223 R-SSC-975829 https://reactome.org/PathwayBrowser/#/R-SSC-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Sus scrofa 58223 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 58223 R-SSC-9845516 https://reactome.org/PathwayBrowser/#/R-SSC-9845516 B3GALT4 transfers Gal to gangliosides IEA Sus scrofa 58223 R-SSC-9846477 https://reactome.org/PathwayBrowser/#/R-SSC-9846477 A4GALT transfers galactose to LacCer IEA Sus scrofa 58223 R-SSC-9846501 https://reactome.org/PathwayBrowser/#/R-SSC-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Sus scrofa 58223 R-SSC-9851347 https://reactome.org/PathwayBrowser/#/R-SSC-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Sus scrofa 58223 R-XTR-162730 https://reactome.org/PathwayBrowser/#/R-XTR-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Xenopus tropicalis 58223 R-XTR-1638104 https://reactome.org/PathwayBrowser/#/R-XTR-1638104 UGCG transfers glucose to ceramide IEA Xenopus tropicalis 58223 R-XTR-1878002 https://reactome.org/PathwayBrowser/#/R-XTR-1878002 XYLTs transfer Xyl to core protein IEA Xenopus tropicalis 58223 R-XTR-1889955 https://reactome.org/PathwayBrowser/#/R-XTR-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Xenopus tropicalis 58223 R-XTR-1889978 https://reactome.org/PathwayBrowser/#/R-XTR-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Xenopus tropicalis 58223 R-XTR-1889981 https://reactome.org/PathwayBrowser/#/R-XTR-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Xenopus tropicalis 58223 R-XTR-1964501 https://reactome.org/PathwayBrowser/#/R-XTR-1964501 Addition of galactose to Core 6 glycoprotein IEA Xenopus tropicalis 58223 R-XTR-1964505 https://reactome.org/PathwayBrowser/#/R-XTR-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Xenopus tropicalis 58223 R-XTR-1971482 https://reactome.org/PathwayBrowser/#/R-XTR-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Xenopus tropicalis 58223 R-XTR-1971487 https://reactome.org/PathwayBrowser/#/R-XTR-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Xenopus tropicalis 58223 R-XTR-1971491 https://reactome.org/PathwayBrowser/#/R-XTR-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Xenopus tropicalis 58223 R-XTR-2025723 https://reactome.org/PathwayBrowser/#/R-XTR-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Xenopus tropicalis 58223 R-XTR-2025724 https://reactome.org/PathwayBrowser/#/R-XTR-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Xenopus tropicalis 58223 R-XTR-2046265 https://reactome.org/PathwayBrowser/#/R-XTR-2046265 B4GALTs transfer Gal to the keratan chain IEA Xenopus tropicalis 58223 R-XTR-2046298 https://reactome.org/PathwayBrowser/#/R-XTR-2046298 B4GALTs transfer Gal to a branch of keratan IEA Xenopus tropicalis 58223 R-XTR-4085021 https://reactome.org/PathwayBrowser/#/R-XTR-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Xenopus tropicalis 58223 R-XTR-446207 https://reactome.org/PathwayBrowser/#/R-XTR-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Xenopus tropicalis 58223 R-XTR-446214 https://reactome.org/PathwayBrowser/#/R-XTR-446214 Synthesis of dolichyl-phosphate-glucose IEA Xenopus tropicalis 58223 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 58223 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 58223 R-XTR-5617037 https://reactome.org/PathwayBrowser/#/R-XTR-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Xenopus tropicalis 58223 R-XTR-5617138 https://reactome.org/PathwayBrowser/#/R-XTR-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Xenopus tropicalis 58223 R-XTR-5617143 https://reactome.org/PathwayBrowser/#/R-XTR-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Xenopus tropicalis 58223 R-XTR-5653878 https://reactome.org/PathwayBrowser/#/R-XTR-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Xenopus tropicalis 58223 R-XTR-5694487 https://reactome.org/PathwayBrowser/#/R-XTR-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Xenopus tropicalis 58223 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 58223 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58223 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58223 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58223 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58223 R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58223 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58223 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58223 R-XTR-8851619 https://reactome.org/PathwayBrowser/#/R-XTR-8851619 GALNT3 transfers GalNAc to FGF23 IEA Xenopus tropicalis 58223 R-XTR-8855954 https://reactome.org/PathwayBrowser/#/R-XTR-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Xenopus tropicalis 58223 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 58223 R-XTR-9033959 https://reactome.org/PathwayBrowser/#/R-XTR-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Xenopus tropicalis 58223 R-XTR-9033961 https://reactome.org/PathwayBrowser/#/R-XTR-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Xenopus tropicalis 58223 R-XTR-9034042 https://reactome.org/PathwayBrowser/#/R-XTR-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Xenopus tropicalis 58223 R-XTR-9034053 https://reactome.org/PathwayBrowser/#/R-XTR-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Xenopus tropicalis 58223 R-XTR-913675 https://reactome.org/PathwayBrowser/#/R-XTR-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Xenopus tropicalis 58223 R-XTR-914005 https://reactome.org/PathwayBrowser/#/R-XTR-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Xenopus tropicalis 58223 R-XTR-914006 https://reactome.org/PathwayBrowser/#/R-XTR-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Xenopus tropicalis 58223 R-XTR-914008 https://reactome.org/PathwayBrowser/#/R-XTR-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Xenopus tropicalis 58223 R-XTR-914010 https://reactome.org/PathwayBrowser/#/R-XTR-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Xenopus tropicalis 58223 R-XTR-914012 https://reactome.org/PathwayBrowser/#/R-XTR-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Xenopus tropicalis 58223 R-XTR-914017 https://reactome.org/PathwayBrowser/#/R-XTR-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Xenopus tropicalis 58223 R-XTR-914018 https://reactome.org/PathwayBrowser/#/R-XTR-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Xenopus tropicalis 58223 R-XTR-9603989 https://reactome.org/PathwayBrowser/#/R-XTR-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Xenopus tropicalis 58223 R-XTR-9605700 https://reactome.org/PathwayBrowser/#/R-XTR-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Xenopus tropicalis 58223 R-XTR-9632033 https://reactome.org/PathwayBrowser/#/R-XTR-9632033 CHSY1 transfers GalNAc to chondroitin IEA Xenopus tropicalis 58223 R-XTR-9632034 https://reactome.org/PathwayBrowser/#/R-XTR-9632034 CHSY1 transfers GlcA to chondroitin IEA Xenopus tropicalis 58223 R-XTR-9638064 https://reactome.org/PathwayBrowser/#/R-XTR-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Xenopus tropicalis 58223 R-XTR-9638090 https://reactome.org/PathwayBrowser/#/R-XTR-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Xenopus tropicalis 58223 R-XTR-9638097 https://reactome.org/PathwayBrowser/#/R-XTR-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Xenopus tropicalis 58223 R-XTR-964768 https://reactome.org/PathwayBrowser/#/R-XTR-964768 Addition of GlcNAc to the glycan on the A arm IEA Xenopus tropicalis 58223 R-XTR-975829 https://reactome.org/PathwayBrowser/#/R-XTR-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Xenopus tropicalis 58223 R-XTR-9845516 https://reactome.org/PathwayBrowser/#/R-XTR-9845516 B3GALT4 transfers Gal to gangliosides IEA Xenopus tropicalis 58223 R-XTR-9846501 https://reactome.org/PathwayBrowser/#/R-XTR-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Xenopus tropicalis 58223 R-XTR-9851347 https://reactome.org/PathwayBrowser/#/R-XTR-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Xenopus tropicalis 58225 R-BTA-198513 https://reactome.org/PathwayBrowser/#/R-BTA-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Bos taurus 58225 R-BTA-3257122 https://reactome.org/PathwayBrowser/#/R-BTA-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Bos taurus 58225 R-BTA-3262512 https://reactome.org/PathwayBrowser/#/R-BTA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Bos taurus 58225 R-BTA-3266566 https://reactome.org/PathwayBrowser/#/R-BTA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Bos taurus 58225 R-BTA-3322041 https://reactome.org/PathwayBrowser/#/R-BTA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Bos taurus 58225 R-BTA-453342 https://reactome.org/PathwayBrowser/#/R-BTA-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Bos taurus 58225 R-BTA-5696021 https://reactome.org/PathwayBrowser/#/R-BTA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Bos taurus 58225 R-BTA-70377 https://reactome.org/PathwayBrowser/#/R-BTA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Bos taurus 58225 R-BTA-70420 https://reactome.org/PathwayBrowser/#/R-BTA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Bos taurus 58225 R-BTA-70471 https://reactome.org/PathwayBrowser/#/R-BTA-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Bos taurus 58225 R-BTA-70475 https://reactome.org/PathwayBrowser/#/R-BTA-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Bos taurus 58225 R-BTA-71825 https://reactome.org/PathwayBrowser/#/R-BTA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Bos taurus 58225 R-BTA-8955760 https://reactome.org/PathwayBrowser/#/R-BTA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Bos taurus 58225 R-CEL-198513 https://reactome.org/PathwayBrowser/#/R-CEL-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Caenorhabditis elegans 58225 R-CEL-3322041 https://reactome.org/PathwayBrowser/#/R-CEL-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Caenorhabditis elegans 58225 R-CEL-453342 https://reactome.org/PathwayBrowser/#/R-CEL-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Caenorhabditis elegans 58225 R-CEL-5696021 https://reactome.org/PathwayBrowser/#/R-CEL-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Caenorhabditis elegans 58225 R-CEL-70377 https://reactome.org/PathwayBrowser/#/R-CEL-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Caenorhabditis elegans 58225 R-CEL-70420 https://reactome.org/PathwayBrowser/#/R-CEL-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Caenorhabditis elegans 58225 R-CEL-70471 https://reactome.org/PathwayBrowser/#/R-CEL-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Caenorhabditis elegans 58225 R-CEL-70475 https://reactome.org/PathwayBrowser/#/R-CEL-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Caenorhabditis elegans 58225 R-CEL-8955760 https://reactome.org/PathwayBrowser/#/R-CEL-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Caenorhabditis elegans 58225 R-CEL-9638125 https://reactome.org/PathwayBrowser/#/R-CEL-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Caenorhabditis elegans 58225 R-CEL-9638127 https://reactome.org/PathwayBrowser/#/R-CEL-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Caenorhabditis elegans 58225 R-CFA-198513 https://reactome.org/PathwayBrowser/#/R-CFA-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Canis familiaris 58225 R-CFA-3257122 https://reactome.org/PathwayBrowser/#/R-CFA-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Canis familiaris 58225 R-CFA-3262512 https://reactome.org/PathwayBrowser/#/R-CFA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Canis familiaris 58225 R-CFA-3266566 https://reactome.org/PathwayBrowser/#/R-CFA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Canis familiaris 58225 R-CFA-3322041 https://reactome.org/PathwayBrowser/#/R-CFA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Canis familiaris 58225 R-CFA-453342 https://reactome.org/PathwayBrowser/#/R-CFA-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Canis familiaris 58225 R-CFA-5696021 https://reactome.org/PathwayBrowser/#/R-CFA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Canis familiaris 58225 R-CFA-70377 https://reactome.org/PathwayBrowser/#/R-CFA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Canis familiaris 58225 R-CFA-70420 https://reactome.org/PathwayBrowser/#/R-CFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Canis familiaris 58225 R-CFA-70471 https://reactome.org/PathwayBrowser/#/R-CFA-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Canis familiaris 58225 R-CFA-70475 https://reactome.org/PathwayBrowser/#/R-CFA-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Canis familiaris 58225 R-CFA-71825 https://reactome.org/PathwayBrowser/#/R-CFA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Canis familiaris 58225 R-CFA-8955760 https://reactome.org/PathwayBrowser/#/R-CFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Canis familiaris 58225 R-DDI-3322041 https://reactome.org/PathwayBrowser/#/R-DDI-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Dictyostelium discoideum 58225 R-DDI-453342 https://reactome.org/PathwayBrowser/#/R-DDI-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Dictyostelium discoideum 58225 R-DDI-5696021 https://reactome.org/PathwayBrowser/#/R-DDI-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Dictyostelium discoideum 58225 R-DDI-70377 https://reactome.org/PathwayBrowser/#/R-DDI-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Dictyostelium discoideum 58225 R-DDI-70471 https://reactome.org/PathwayBrowser/#/R-DDI-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Dictyostelium discoideum 58225 R-DDI-70475 https://reactome.org/PathwayBrowser/#/R-DDI-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Dictyostelium discoideum 58225 R-DDI-8955760 https://reactome.org/PathwayBrowser/#/R-DDI-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Dictyostelium discoideum 58225 R-DDI-9638125 https://reactome.org/PathwayBrowser/#/R-DDI-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Dictyostelium discoideum 58225 R-DDI-9638127 https://reactome.org/PathwayBrowser/#/R-DDI-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Dictyostelium discoideum 58225 R-DME-3257122 https://reactome.org/PathwayBrowser/#/R-DME-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Drosophila melanogaster 58225 R-DME-3262512 https://reactome.org/PathwayBrowser/#/R-DME-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Drosophila melanogaster 58225 R-DME-3266566 https://reactome.org/PathwayBrowser/#/R-DME-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Drosophila melanogaster 58225 R-DME-3322041 https://reactome.org/PathwayBrowser/#/R-DME-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Drosophila melanogaster 58225 R-DME-453342 https://reactome.org/PathwayBrowser/#/R-DME-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Drosophila melanogaster 58225 R-DME-70377 https://reactome.org/PathwayBrowser/#/R-DME-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Drosophila melanogaster 58225 R-DME-70420 https://reactome.org/PathwayBrowser/#/R-DME-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Drosophila melanogaster 58225 R-DME-70471 https://reactome.org/PathwayBrowser/#/R-DME-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Drosophila melanogaster 58225 R-DME-70475 https://reactome.org/PathwayBrowser/#/R-DME-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Drosophila melanogaster 58225 R-DME-71825 https://reactome.org/PathwayBrowser/#/R-DME-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Drosophila melanogaster 58225 R-DME-8955760 https://reactome.org/PathwayBrowser/#/R-DME-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Drosophila melanogaster 58225 R-DME-9638125 https://reactome.org/PathwayBrowser/#/R-DME-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Drosophila melanogaster 58225 R-DME-9638127 https://reactome.org/PathwayBrowser/#/R-DME-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Drosophila melanogaster 58225 R-DRE-198513 https://reactome.org/PathwayBrowser/#/R-DRE-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Danio rerio 58225 R-DRE-3257122 https://reactome.org/PathwayBrowser/#/R-DRE-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Danio rerio 58225 R-DRE-3262512 https://reactome.org/PathwayBrowser/#/R-DRE-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Danio rerio 58225 R-DRE-3322041 https://reactome.org/PathwayBrowser/#/R-DRE-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Danio rerio 58225 R-DRE-453342 https://reactome.org/PathwayBrowser/#/R-DRE-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Danio rerio 58225 R-DRE-5696021 https://reactome.org/PathwayBrowser/#/R-DRE-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Danio rerio 58225 R-DRE-70420 https://reactome.org/PathwayBrowser/#/R-DRE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Danio rerio 58225 R-DRE-70471 https://reactome.org/PathwayBrowser/#/R-DRE-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Danio rerio 58225 R-DRE-70475 https://reactome.org/PathwayBrowser/#/R-DRE-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Danio rerio 58225 R-DRE-8955760 https://reactome.org/PathwayBrowser/#/R-DRE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Danio rerio 58225 R-DRE-9638125 https://reactome.org/PathwayBrowser/#/R-DRE-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Danio rerio 58225 R-DRE-9638127 https://reactome.org/PathwayBrowser/#/R-DRE-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Danio rerio 58225 R-GGA-198513 https://reactome.org/PathwayBrowser/#/R-GGA-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Gallus gallus 58225 R-GGA-3257122 https://reactome.org/PathwayBrowser/#/R-GGA-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Gallus gallus 58225 R-GGA-3262512 https://reactome.org/PathwayBrowser/#/R-GGA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Gallus gallus 58225 R-GGA-3266566 https://reactome.org/PathwayBrowser/#/R-GGA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Gallus gallus 58225 R-GGA-3322041 https://reactome.org/PathwayBrowser/#/R-GGA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Gallus gallus 58225 R-GGA-352840 https://reactome.org/PathwayBrowser/#/R-GGA-352840 glucose + ATP => glucose 6-phosphate + ADP TAS Gallus gallus 58225 R-GGA-352872 https://reactome.org/PathwayBrowser/#/R-GGA-352872 fructose 6-phosphate <=> glucose 6-phosphate TAS Gallus gallus 58225 R-GGA-352893 https://reactome.org/PathwayBrowser/#/R-GGA-352893 glucose 6-phosphate <=> fructose 6-phosphate TAS Gallus gallus 58225 R-GGA-353058 https://reactome.org/PathwayBrowser/#/R-GGA-353058 glucose 6-phosphate + H2O => glucose + phosphate IEA Gallus gallus 58225 R-GGA-376884 https://reactome.org/PathwayBrowser/#/R-GGA-376884 glucose 6-phosphate [cytosol] => glucose 6-phosphate [endoplasmic reticulum lumen] IEA Gallus gallus 58225 R-GGA-5696021 https://reactome.org/PathwayBrowser/#/R-GGA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Gallus gallus 58225 R-GGA-70420 https://reactome.org/PathwayBrowser/#/R-GGA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Gallus gallus 58225 R-GGA-70471 https://reactome.org/PathwayBrowser/#/R-GGA-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Gallus gallus 58225 R-GGA-70475 https://reactome.org/PathwayBrowser/#/R-GGA-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Gallus gallus 58225 R-GGA-71825 https://reactome.org/PathwayBrowser/#/R-GGA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Gallus gallus 58225 R-GGA-8955760 https://reactome.org/PathwayBrowser/#/R-GGA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Gallus gallus 58225 R-GGA-9638125 https://reactome.org/PathwayBrowser/#/R-GGA-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Gallus gallus 58225 R-GGA-9638127 https://reactome.org/PathwayBrowser/#/R-GGA-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Gallus gallus 58225 R-HSA-1500781 https://reactome.org/PathwayBrowser/#/R-HSA-1500781 Fgd1 reactivates F420 TAS Homo sapiens 58225 R-HSA-198513 https://reactome.org/PathwayBrowser/#/R-HSA-198513 SLC7A4 exchanges G6P for Pi across the ER membrane TAS Homo sapiens 58225 R-HSA-3229118 https://reactome.org/PathwayBrowser/#/R-HSA-3229118 Defective SLC37A4 does not exchange G6P and Pi across the ER membrane TAS Homo sapiens 58225 R-HSA-3257122 https://reactome.org/PathwayBrowser/#/R-HSA-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane TAS Homo sapiens 58225 R-HSA-3262512 https://reactome.org/PathwayBrowser/#/R-HSA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) TAS Homo sapiens 58225 R-HSA-3266566 https://reactome.org/PathwayBrowser/#/R-HSA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) TAS Homo sapiens 58225 R-HSA-3274540 https://reactome.org/PathwayBrowser/#/R-HSA-3274540 Defective G6PC does not hydrolyze glucose 6-phosphate TAS Homo sapiens 58225 R-HSA-3282876 https://reactome.org/PathwayBrowser/#/R-HSA-3282876 Defective G6PC3 does not hydrolyze glucose 6-phosphate TAS Homo sapiens 58225 R-HSA-3322041 https://reactome.org/PathwayBrowser/#/R-HSA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 TAS Homo sapiens 58225 R-HSA-453342 https://reactome.org/PathwayBrowser/#/R-HSA-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex TAS Homo sapiens 58225 R-HSA-5609939 https://reactome.org/PathwayBrowser/#/R-HSA-5609939 Defective PGM1 does not isomerise G6P to G1P TAS Homo sapiens 58225 R-HSA-5696021 https://reactome.org/PathwayBrowser/#/R-HSA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P TAS Homo sapiens 58225 R-HSA-70377 https://reactome.org/PathwayBrowser/#/R-HSA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ TAS Homo sapiens 58225 R-HSA-70420 https://reactome.org/PathwayBrowser/#/R-HSA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P TAS Homo sapiens 58225 R-HSA-70471 https://reactome.org/PathwayBrowser/#/R-HSA-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate TAS Homo sapiens 58225 R-HSA-70475 https://reactome.org/PathwayBrowser/#/R-HSA-70475 GPI dimer isomerizes Fru(6)P to G6P TAS Homo sapiens 58225 R-HSA-71825 https://reactome.org/PathwayBrowser/#/R-HSA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) TAS Homo sapiens 58225 R-HSA-8955760 https://reactome.org/PathwayBrowser/#/R-HSA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP TAS Homo sapiens 58225 R-HSA-9638125 https://reactome.org/PathwayBrowser/#/R-HSA-9638125 PGM1:Mg2+ isomerises G1P to G6P TAS Homo sapiens 58225 R-HSA-9638127 https://reactome.org/PathwayBrowser/#/R-HSA-9638127 PGM1:Mg2+ isomerises G6P to G1P TAS Homo sapiens 58225 R-MMU-198513 https://reactome.org/PathwayBrowser/#/R-MMU-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Mus musculus 58225 R-MMU-3257122 https://reactome.org/PathwayBrowser/#/R-MMU-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Mus musculus 58225 R-MMU-3262512 https://reactome.org/PathwayBrowser/#/R-MMU-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Mus musculus 58225 R-MMU-3266566 https://reactome.org/PathwayBrowser/#/R-MMU-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Mus musculus 58225 R-MMU-3322041 https://reactome.org/PathwayBrowser/#/R-MMU-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Mus musculus 58225 R-MMU-453342 https://reactome.org/PathwayBrowser/#/R-MMU-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Mus musculus 58225 R-MMU-5696021 https://reactome.org/PathwayBrowser/#/R-MMU-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Mus musculus 58225 R-MMU-70377 https://reactome.org/PathwayBrowser/#/R-MMU-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Mus musculus 58225 R-MMU-70420 https://reactome.org/PathwayBrowser/#/R-MMU-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Mus musculus 58225 R-MMU-70471 https://reactome.org/PathwayBrowser/#/R-MMU-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Mus musculus 58225 R-MMU-70475 https://reactome.org/PathwayBrowser/#/R-MMU-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Mus musculus 58225 R-MMU-71825 https://reactome.org/PathwayBrowser/#/R-MMU-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Mus musculus 58225 R-MMU-8955760 https://reactome.org/PathwayBrowser/#/R-MMU-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Mus musculus 58225 R-MMU-9638125 https://reactome.org/PathwayBrowser/#/R-MMU-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Mus musculus 58225 R-MMU-9638127 https://reactome.org/PathwayBrowser/#/R-MMU-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Mus musculus 58225 R-MTU-868622 https://reactome.org/PathwayBrowser/#/R-MTU-868622 Glucose is transferred from UDP-glucose onto glucose-6-phosphate TAS Mycobacterium tuberculosis 58225 R-MTU-879331 https://reactome.org/PathwayBrowser/#/R-MTU-879331 glucose-6-phosphate is converted to inositol-1-phosphate TAS Mycobacterium tuberculosis 58225 R-PFA-70377 https://reactome.org/PathwayBrowser/#/R-PFA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Plasmodium falciparum 58225 R-PFA-70420 https://reactome.org/PathwayBrowser/#/R-PFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Plasmodium falciparum 58225 R-PFA-70471 https://reactome.org/PathwayBrowser/#/R-PFA-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Plasmodium falciparum 58225 R-PFA-70475 https://reactome.org/PathwayBrowser/#/R-PFA-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Plasmodium falciparum 58225 R-PFA-8955760 https://reactome.org/PathwayBrowser/#/R-PFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Plasmodium falciparum 58225 R-RNO-198513 https://reactome.org/PathwayBrowser/#/R-RNO-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Rattus norvegicus 58225 R-RNO-3257122 https://reactome.org/PathwayBrowser/#/R-RNO-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Rattus norvegicus 58225 R-RNO-3262512 https://reactome.org/PathwayBrowser/#/R-RNO-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Rattus norvegicus 58225 R-RNO-3322041 https://reactome.org/PathwayBrowser/#/R-RNO-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Rattus norvegicus 58225 R-RNO-453342 https://reactome.org/PathwayBrowser/#/R-RNO-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Rattus norvegicus 58225 R-RNO-5696021 https://reactome.org/PathwayBrowser/#/R-RNO-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Rattus norvegicus 58225 R-RNO-70377 https://reactome.org/PathwayBrowser/#/R-RNO-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Rattus norvegicus 58225 R-RNO-70420 https://reactome.org/PathwayBrowser/#/R-RNO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Rattus norvegicus 58225 R-RNO-70471 https://reactome.org/PathwayBrowser/#/R-RNO-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Rattus norvegicus 58225 R-RNO-70475 https://reactome.org/PathwayBrowser/#/R-RNO-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Rattus norvegicus 58225 R-RNO-71825 https://reactome.org/PathwayBrowser/#/R-RNO-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Rattus norvegicus 58225 R-RNO-8955760 https://reactome.org/PathwayBrowser/#/R-RNO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Rattus norvegicus 58225 R-RNO-9638125 https://reactome.org/PathwayBrowser/#/R-RNO-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Rattus norvegicus 58225 R-RNO-9638127 https://reactome.org/PathwayBrowser/#/R-RNO-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Rattus norvegicus 58225 R-SCE-3322041 https://reactome.org/PathwayBrowser/#/R-SCE-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Saccharomyces cerevisiae 58225 R-SCE-453342 https://reactome.org/PathwayBrowser/#/R-SCE-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Saccharomyces cerevisiae 58225 R-SCE-70377 https://reactome.org/PathwayBrowser/#/R-SCE-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Saccharomyces cerevisiae 58225 R-SCE-70420 https://reactome.org/PathwayBrowser/#/R-SCE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Saccharomyces cerevisiae 58225 R-SCE-70471 https://reactome.org/PathwayBrowser/#/R-SCE-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Saccharomyces cerevisiae 58225 R-SCE-70475 https://reactome.org/PathwayBrowser/#/R-SCE-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Saccharomyces cerevisiae 58225 R-SCE-8955760 https://reactome.org/PathwayBrowser/#/R-SCE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Saccharomyces cerevisiae 58225 R-SCE-9638125 https://reactome.org/PathwayBrowser/#/R-SCE-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Saccharomyces cerevisiae 58225 R-SCE-9638127 https://reactome.org/PathwayBrowser/#/R-SCE-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Saccharomyces cerevisiae 58225 R-SPO-70377 https://reactome.org/PathwayBrowser/#/R-SPO-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Schizosaccharomyces pombe 58225 R-SPO-70420 https://reactome.org/PathwayBrowser/#/R-SPO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Schizosaccharomyces pombe 58225 R-SPO-70471 https://reactome.org/PathwayBrowser/#/R-SPO-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Schizosaccharomyces pombe 58225 R-SPO-70475 https://reactome.org/PathwayBrowser/#/R-SPO-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Schizosaccharomyces pombe 58225 R-SPO-8955760 https://reactome.org/PathwayBrowser/#/R-SPO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Schizosaccharomyces pombe 58225 R-SPO-9638125 https://reactome.org/PathwayBrowser/#/R-SPO-9638125 PGM1:Mg2+ isomerises G1P to G6P IEA Schizosaccharomyces pombe 58225 R-SPO-9638127 https://reactome.org/PathwayBrowser/#/R-SPO-9638127 PGM1:Mg2+ isomerises G6P to G1P IEA Schizosaccharomyces pombe 58225 R-SSC-198513 https://reactome.org/PathwayBrowser/#/R-SSC-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Sus scrofa 58225 R-SSC-3257122 https://reactome.org/PathwayBrowser/#/R-SSC-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Sus scrofa 58225 R-SSC-3262512 https://reactome.org/PathwayBrowser/#/R-SSC-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Sus scrofa 58225 R-SSC-3266566 https://reactome.org/PathwayBrowser/#/R-SSC-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Sus scrofa 58225 R-SSC-3322041 https://reactome.org/PathwayBrowser/#/R-SSC-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Sus scrofa 58225 R-SSC-453342 https://reactome.org/PathwayBrowser/#/R-SSC-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Sus scrofa 58225 R-SSC-5696021 https://reactome.org/PathwayBrowser/#/R-SSC-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Sus scrofa 58225 R-SSC-70377 https://reactome.org/PathwayBrowser/#/R-SSC-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Sus scrofa 58225 R-SSC-70420 https://reactome.org/PathwayBrowser/#/R-SSC-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Sus scrofa 58225 R-SSC-70471 https://reactome.org/PathwayBrowser/#/R-SSC-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Sus scrofa 58225 R-SSC-70475 https://reactome.org/PathwayBrowser/#/R-SSC-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Sus scrofa 58225 R-SSC-71825 https://reactome.org/PathwayBrowser/#/R-SSC-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Sus scrofa 58225 R-SSC-8955760 https://reactome.org/PathwayBrowser/#/R-SSC-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Sus scrofa 58225 R-XTR-198513 https://reactome.org/PathwayBrowser/#/R-XTR-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Xenopus tropicalis 58225 R-XTR-3257122 https://reactome.org/PathwayBrowser/#/R-XTR-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Xenopus tropicalis 58225 R-XTR-453342 https://reactome.org/PathwayBrowser/#/R-XTR-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex IEA Xenopus tropicalis 58225 R-XTR-5696021 https://reactome.org/PathwayBrowser/#/R-XTR-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Xenopus tropicalis 58225 R-XTR-70377 https://reactome.org/PathwayBrowser/#/R-XTR-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Xenopus tropicalis 58225 R-XTR-70420 https://reactome.org/PathwayBrowser/#/R-XTR-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Xenopus tropicalis 58225 R-XTR-70471 https://reactome.org/PathwayBrowser/#/R-XTR-70471 alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate IEA Xenopus tropicalis 58225 R-XTR-70475 https://reactome.org/PathwayBrowser/#/R-XTR-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Xenopus tropicalis 58225 R-XTR-71825 https://reactome.org/PathwayBrowser/#/R-XTR-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Xenopus tropicalis 58225 R-XTR-8955760 https://reactome.org/PathwayBrowser/#/R-XTR-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Xenopus tropicalis 58228 R-BTA-70555 https://reactome.org/PathwayBrowser/#/R-BTA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Bos taurus 58228 R-BTA-70560 https://reactome.org/PathwayBrowser/#/R-BTA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Bos taurus 58228 R-BTA-73573 https://reactome.org/PathwayBrowser/#/R-BTA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Bos taurus 58228 R-BTA-73577 https://reactome.org/PathwayBrowser/#/R-BTA-73577 CAD hexamer transforms L-Gln to CAP IEA Bos taurus 58228 R-CEL-73573 https://reactome.org/PathwayBrowser/#/R-CEL-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Caenorhabditis elegans 58228 R-CEL-73577 https://reactome.org/PathwayBrowser/#/R-CEL-73577 CAD hexamer transforms L-Gln to CAP IEA Caenorhabditis elegans 58228 R-CFA-70555 https://reactome.org/PathwayBrowser/#/R-CFA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Canis familiaris 58228 R-CFA-70560 https://reactome.org/PathwayBrowser/#/R-CFA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Canis familiaris 58228 R-CFA-73573 https://reactome.org/PathwayBrowser/#/R-CFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Canis familiaris 58228 R-CFA-73577 https://reactome.org/PathwayBrowser/#/R-CFA-73577 CAD hexamer transforms L-Gln to CAP IEA Canis familiaris 58228 R-DDI-73573 https://reactome.org/PathwayBrowser/#/R-DDI-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Dictyostelium discoideum 58228 R-DDI-73577 https://reactome.org/PathwayBrowser/#/R-DDI-73577 CAD hexamer transforms L-Gln to CAP IEA Dictyostelium discoideum 58228 R-DME-73573 https://reactome.org/PathwayBrowser/#/R-DME-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Drosophila melanogaster 58228 R-DME-73577 https://reactome.org/PathwayBrowser/#/R-DME-73577 CAD hexamer transforms L-Gln to CAP IEA Drosophila melanogaster 58228 R-GGA-187588 https://reactome.org/PathwayBrowser/#/R-GGA-187588 carbamoyl phosphate + ornithine => citrulline + orthophosphate TAS Gallus gallus 58228 R-GGA-419440 https://reactome.org/PathwayBrowser/#/R-GGA-419440 L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate IEA Gallus gallus 58228 R-GGA-419451 https://reactome.org/PathwayBrowser/#/R-GGA-419451 carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate IEA Gallus gallus 58228 R-GGA-70555 https://reactome.org/PathwayBrowser/#/R-GGA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Gallus gallus 58228 R-GGA-70560 https://reactome.org/PathwayBrowser/#/R-GGA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Gallus gallus 58228 R-HSA-70555 https://reactome.org/PathwayBrowser/#/R-HSA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] TAS Homo sapiens 58228 R-HSA-70560 https://reactome.org/PathwayBrowser/#/R-HSA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate TAS Homo sapiens 58228 R-HSA-73573 https://reactome.org/PathwayBrowser/#/R-HSA-73573 CAD hexamer transforms CAP to N-carb-L-Asp TAS Homo sapiens 58228 R-HSA-73577 https://reactome.org/PathwayBrowser/#/R-HSA-73577 CAD hexamer transforms L-Gln to CAP TAS Homo sapiens 58228 R-MMU-70555 https://reactome.org/PathwayBrowser/#/R-MMU-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Mus musculus 58228 R-MMU-70560 https://reactome.org/PathwayBrowser/#/R-MMU-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Mus musculus 58228 R-MMU-73573 https://reactome.org/PathwayBrowser/#/R-MMU-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Mus musculus 58228 R-MMU-73577 https://reactome.org/PathwayBrowser/#/R-MMU-73577 CAD hexamer transforms L-Gln to CAP IEA Mus musculus 58228 R-PFA-73573 https://reactome.org/PathwayBrowser/#/R-PFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Plasmodium falciparum 58228 R-PFA-73577 https://reactome.org/PathwayBrowser/#/R-PFA-73577 CAD hexamer transforms L-Gln to CAP IEA Plasmodium falciparum 58228 R-RNO-70555 https://reactome.org/PathwayBrowser/#/R-RNO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Rattus norvegicus 58228 R-RNO-70560 https://reactome.org/PathwayBrowser/#/R-RNO-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Rattus norvegicus 58228 R-RNO-73573 https://reactome.org/PathwayBrowser/#/R-RNO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Rattus norvegicus 58228 R-RNO-73577 https://reactome.org/PathwayBrowser/#/R-RNO-73577 CAD hexamer transforms L-Gln to CAP IEA Rattus norvegicus 58228 R-SCE-70555 https://reactome.org/PathwayBrowser/#/R-SCE-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Saccharomyces cerevisiae 58228 R-SCE-70560 https://reactome.org/PathwayBrowser/#/R-SCE-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Saccharomyces cerevisiae 58228 R-SCE-73573 https://reactome.org/PathwayBrowser/#/R-SCE-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Saccharomyces cerevisiae 58228 R-SCE-73577 https://reactome.org/PathwayBrowser/#/R-SCE-73577 CAD hexamer transforms L-Gln to CAP IEA Saccharomyces cerevisiae 58228 R-SPO-70555 https://reactome.org/PathwayBrowser/#/R-SPO-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Schizosaccharomyces pombe 58228 R-SPO-70560 https://reactome.org/PathwayBrowser/#/R-SPO-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Schizosaccharomyces pombe 58228 R-SPO-73573 https://reactome.org/PathwayBrowser/#/R-SPO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Schizosaccharomyces pombe 58228 R-SPO-73577 https://reactome.org/PathwayBrowser/#/R-SPO-73577 CAD hexamer transforms L-Gln to CAP IEA Schizosaccharomyces pombe 58228 R-SSC-70555 https://reactome.org/PathwayBrowser/#/R-SSC-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Sus scrofa 58228 R-SSC-70560 https://reactome.org/PathwayBrowser/#/R-SSC-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Sus scrofa 58228 R-SSC-73573 https://reactome.org/PathwayBrowser/#/R-SSC-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Sus scrofa 58228 R-SSC-73577 https://reactome.org/PathwayBrowser/#/R-SSC-73577 CAD hexamer transforms L-Gln to CAP IEA Sus scrofa 58228 R-XTR-70555 https://reactome.org/PathwayBrowser/#/R-XTR-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] IEA Xenopus tropicalis 58228 R-XTR-70560 https://reactome.org/PathwayBrowser/#/R-XTR-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate IEA Xenopus tropicalis 58228 R-XTR-73573 https://reactome.org/PathwayBrowser/#/R-XTR-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Xenopus tropicalis 58228 R-XTR-73577 https://reactome.org/PathwayBrowser/#/R-XTR-73577 CAD hexamer transforms L-Gln to CAP IEA Xenopus tropicalis 58243 R-BTA-174389 https://reactome.org/PathwayBrowser/#/R-BTA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Bos taurus 58243 R-BTA-174392 https://reactome.org/PathwayBrowser/#/R-BTA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Bos taurus 58243 R-CEL-174389 https://reactome.org/PathwayBrowser/#/R-CEL-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Caenorhabditis elegans 58243 R-CEL-174392 https://reactome.org/PathwayBrowser/#/R-CEL-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Caenorhabditis elegans 58243 R-CFA-174389 https://reactome.org/PathwayBrowser/#/R-CFA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Canis familiaris 58243 R-CFA-174392 https://reactome.org/PathwayBrowser/#/R-CFA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Canis familiaris 58243 R-DME-174389 https://reactome.org/PathwayBrowser/#/R-DME-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Drosophila melanogaster 58243 R-DME-174392 https://reactome.org/PathwayBrowser/#/R-DME-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Drosophila melanogaster 58243 R-DRE-174389 https://reactome.org/PathwayBrowser/#/R-DRE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Danio rerio 58243 R-DRE-174392 https://reactome.org/PathwayBrowser/#/R-DRE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Danio rerio 58243 R-GGA-174389 https://reactome.org/PathwayBrowser/#/R-GGA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Gallus gallus 58243 R-GGA-174392 https://reactome.org/PathwayBrowser/#/R-GGA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Gallus gallus 58243 R-HSA-174389 https://reactome.org/PathwayBrowser/#/R-HSA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS TAS Homo sapiens 58243 R-HSA-174392 https://reactome.org/PathwayBrowser/#/R-HSA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS TAS Homo sapiens 58243 R-HSA-3560785 https://reactome.org/PathwayBrowser/#/R-HSA-3560785 Defective PAPSS2 does not transfer PO4(2-) group from ATP to APS to form PAPS TAS Homo sapiens 58243 R-MMU-174389 https://reactome.org/PathwayBrowser/#/R-MMU-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Mus musculus 58243 R-MMU-174392 https://reactome.org/PathwayBrowser/#/R-MMU-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Mus musculus 58243 R-MTU-936583 https://reactome.org/PathwayBrowser/#/R-MTU-936583 APS is phosphorylated to PAPS TAS Mycobacterium tuberculosis 58243 R-MTU-936655 https://reactome.org/PathwayBrowser/#/R-MTU-936655 sulfite results from reduction of APS TAS Mycobacterium tuberculosis 58243 R-MTU-936659 https://reactome.org/PathwayBrowser/#/R-MTU-936659 PAPS is dephosphorylated to APS TAS Mycobacterium tuberculosis 58243 R-MTU-936729 https://reactome.org/PathwayBrowser/#/R-MTU-936729 sulfate is activated to APS TAS Mycobacterium tuberculosis 58243 R-RNO-174389 https://reactome.org/PathwayBrowser/#/R-RNO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Rattus norvegicus 58243 R-RNO-174392 https://reactome.org/PathwayBrowser/#/R-RNO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Rattus norvegicus 58243 R-SCE-174389 https://reactome.org/PathwayBrowser/#/R-SCE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Saccharomyces cerevisiae 58243 R-SCE-174392 https://reactome.org/PathwayBrowser/#/R-SCE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Saccharomyces cerevisiae 58243 R-SPO-174389 https://reactome.org/PathwayBrowser/#/R-SPO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Schizosaccharomyces pombe 58243 R-SPO-174392 https://reactome.org/PathwayBrowser/#/R-SPO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Schizosaccharomyces pombe 58243 R-SSC-174389 https://reactome.org/PathwayBrowser/#/R-SSC-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Sus scrofa 58243 R-SSC-174392 https://reactome.org/PathwayBrowser/#/R-SSC-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Sus scrofa 58243 R-XTR-174389 https://reactome.org/PathwayBrowser/#/R-XTR-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Xenopus tropicalis 58243 R-XTR-174392 https://reactome.org/PathwayBrowser/#/R-XTR-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Xenopus tropicalis 58245 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 58245 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 58245 R-BTA-109624 https://reactome.org/PathwayBrowser/#/R-BTA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Bos taurus 58245 R-BTA-109671 https://reactome.org/PathwayBrowser/#/R-BTA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Bos taurus 58245 R-BTA-110137 https://reactome.org/PathwayBrowser/#/R-BTA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Bos taurus 58245 R-BTA-110138 https://reactome.org/PathwayBrowser/#/R-BTA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 58245 R-BTA-110141 https://reactome.org/PathwayBrowser/#/R-BTA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Bos taurus 58245 R-BTA-111215 https://reactome.org/PathwayBrowser/#/R-BTA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Bos taurus 58245 R-BTA-6788798 https://reactome.org/PathwayBrowser/#/R-BTA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 58245 R-BTA-6788810 https://reactome.org/PathwayBrowser/#/R-BTA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 58245 R-BTA-74207 https://reactome.org/PathwayBrowser/#/R-BTA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Bos taurus 58245 R-BTA-74220 https://reactome.org/PathwayBrowser/#/R-BTA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Bos taurus 58245 R-CEL-109624 https://reactome.org/PathwayBrowser/#/R-CEL-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Caenorhabditis elegans 58245 R-CEL-110137 https://reactome.org/PathwayBrowser/#/R-CEL-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Caenorhabditis elegans 58245 R-CEL-110138 https://reactome.org/PathwayBrowser/#/R-CEL-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 58245 R-CEL-110141 https://reactome.org/PathwayBrowser/#/R-CEL-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Caenorhabditis elegans 58245 R-CEL-6788810 https://reactome.org/PathwayBrowser/#/R-CEL-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 58245 R-CEL-74220 https://reactome.org/PathwayBrowser/#/R-CEL-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Caenorhabditis elegans 58245 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 58245 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 58245 R-CFA-109624 https://reactome.org/PathwayBrowser/#/R-CFA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Canis familiaris 58245 R-CFA-109671 https://reactome.org/PathwayBrowser/#/R-CFA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Canis familiaris 58245 R-CFA-110137 https://reactome.org/PathwayBrowser/#/R-CFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Canis familiaris 58245 R-CFA-110138 https://reactome.org/PathwayBrowser/#/R-CFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 58245 R-CFA-110141 https://reactome.org/PathwayBrowser/#/R-CFA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Canis familiaris 58245 R-CFA-111215 https://reactome.org/PathwayBrowser/#/R-CFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Canis familiaris 58245 R-CFA-6788798 https://reactome.org/PathwayBrowser/#/R-CFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 58245 R-CFA-6788810 https://reactome.org/PathwayBrowser/#/R-CFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 58245 R-CFA-74207 https://reactome.org/PathwayBrowser/#/R-CFA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Canis familiaris 58245 R-CFA-74220 https://reactome.org/PathwayBrowser/#/R-CFA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Canis familiaris 58245 R-DDI-109624 https://reactome.org/PathwayBrowser/#/R-DDI-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Dictyostelium discoideum 58245 R-DDI-111215 https://reactome.org/PathwayBrowser/#/R-DDI-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Dictyostelium discoideum 58245 R-DDI-6788798 https://reactome.org/PathwayBrowser/#/R-DDI-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 58245 R-DDI-6788810 https://reactome.org/PathwayBrowser/#/R-DDI-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 58245 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 58245 R-DME-109624 https://reactome.org/PathwayBrowser/#/R-DME-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Drosophila melanogaster 58245 R-DME-110137 https://reactome.org/PathwayBrowser/#/R-DME-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Drosophila melanogaster 58245 R-DME-110138 https://reactome.org/PathwayBrowser/#/R-DME-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 58245 R-DME-110141 https://reactome.org/PathwayBrowser/#/R-DME-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Drosophila melanogaster 58245 R-DME-6788798 https://reactome.org/PathwayBrowser/#/R-DME-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 58245 R-DME-6788810 https://reactome.org/PathwayBrowser/#/R-DME-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 58245 R-DME-74220 https://reactome.org/PathwayBrowser/#/R-DME-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Drosophila melanogaster 58245 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 58245 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 58245 R-DRE-109624 https://reactome.org/PathwayBrowser/#/R-DRE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Danio rerio 58245 R-DRE-109671 https://reactome.org/PathwayBrowser/#/R-DRE-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Danio rerio 58245 R-DRE-110137 https://reactome.org/PathwayBrowser/#/R-DRE-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Danio rerio 58245 R-DRE-110138 https://reactome.org/PathwayBrowser/#/R-DRE-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 58245 R-DRE-111215 https://reactome.org/PathwayBrowser/#/R-DRE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Danio rerio 58245 R-DRE-6788798 https://reactome.org/PathwayBrowser/#/R-DRE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 58245 R-DRE-6788810 https://reactome.org/PathwayBrowser/#/R-DRE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 58245 R-DRE-74207 https://reactome.org/PathwayBrowser/#/R-DRE-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Danio rerio 58245 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 58245 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 58245 R-GGA-109624 https://reactome.org/PathwayBrowser/#/R-GGA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Gallus gallus 58245 R-GGA-109671 https://reactome.org/PathwayBrowser/#/R-GGA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Gallus gallus 58245 R-GGA-110137 https://reactome.org/PathwayBrowser/#/R-GGA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Gallus gallus 58245 R-GGA-110138 https://reactome.org/PathwayBrowser/#/R-GGA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 58245 R-GGA-110141 https://reactome.org/PathwayBrowser/#/R-GGA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Gallus gallus 58245 R-GGA-111215 https://reactome.org/PathwayBrowser/#/R-GGA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Gallus gallus 58245 R-GGA-6788798 https://reactome.org/PathwayBrowser/#/R-GGA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 58245 R-GGA-6788810 https://reactome.org/PathwayBrowser/#/R-GGA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 58245 R-GGA-74220 https://reactome.org/PathwayBrowser/#/R-GGA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Gallus gallus 58245 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 58245 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 58245 R-HSA-109624 https://reactome.org/PathwayBrowser/#/R-HSA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) TAS Homo sapiens 58245 R-HSA-109671 https://reactome.org/PathwayBrowser/#/R-HSA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) TAS Homo sapiens 58245 R-HSA-110137 https://reactome.org/PathwayBrowser/#/R-HSA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP TAS Homo sapiens 58245 R-HSA-110138 https://reactome.org/PathwayBrowser/#/R-HSA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 58245 R-HSA-110141 https://reactome.org/PathwayBrowser/#/R-HSA-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) TAS Homo sapiens 58245 R-HSA-111215 https://reactome.org/PathwayBrowser/#/R-HSA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate TAS Homo sapiens 58245 R-HSA-3245943 https://reactome.org/PathwayBrowser/#/R-HSA-3245943 Viral DNA cleavage by TREX1 TAS Homo sapiens 58245 R-HSA-6788798 https://reactome.org/PathwayBrowser/#/R-HSA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 58245 R-HSA-6788810 https://reactome.org/PathwayBrowser/#/R-HSA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 58245 R-HSA-74207 https://reactome.org/PathwayBrowser/#/R-HSA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) TAS Homo sapiens 58245 R-HSA-74220 https://reactome.org/PathwayBrowser/#/R-HSA-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) TAS Homo sapiens 58245 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 58245 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 58245 R-MMU-109624 https://reactome.org/PathwayBrowser/#/R-MMU-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Mus musculus 58245 R-MMU-109671 https://reactome.org/PathwayBrowser/#/R-MMU-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Mus musculus 58245 R-MMU-110137 https://reactome.org/PathwayBrowser/#/R-MMU-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Mus musculus 58245 R-MMU-110138 https://reactome.org/PathwayBrowser/#/R-MMU-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 58245 R-MMU-110141 https://reactome.org/PathwayBrowser/#/R-MMU-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Mus musculus 58245 R-MMU-111215 https://reactome.org/PathwayBrowser/#/R-MMU-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Mus musculus 58245 R-MMU-6788798 https://reactome.org/PathwayBrowser/#/R-MMU-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 58245 R-MMU-6788810 https://reactome.org/PathwayBrowser/#/R-MMU-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 58245 R-MMU-74207 https://reactome.org/PathwayBrowser/#/R-MMU-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Mus musculus 58245 R-MMU-74220 https://reactome.org/PathwayBrowser/#/R-MMU-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Mus musculus 58245 R-PFA-110137 https://reactome.org/PathwayBrowser/#/R-PFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Plasmodium falciparum 58245 R-PFA-110138 https://reactome.org/PathwayBrowser/#/R-PFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 58245 R-PFA-111215 https://reactome.org/PathwayBrowser/#/R-PFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Plasmodium falciparum 58245 R-PFA-6788798 https://reactome.org/PathwayBrowser/#/R-PFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 58245 R-PFA-6788810 https://reactome.org/PathwayBrowser/#/R-PFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 58245 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 58245 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 58245 R-RNO-109624 https://reactome.org/PathwayBrowser/#/R-RNO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Rattus norvegicus 58245 R-RNO-109671 https://reactome.org/PathwayBrowser/#/R-RNO-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Rattus norvegicus 58245 R-RNO-110137 https://reactome.org/PathwayBrowser/#/R-RNO-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Rattus norvegicus 58245 R-RNO-110138 https://reactome.org/PathwayBrowser/#/R-RNO-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 58245 R-RNO-110141 https://reactome.org/PathwayBrowser/#/R-RNO-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Rattus norvegicus 58245 R-RNO-111215 https://reactome.org/PathwayBrowser/#/R-RNO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Rattus norvegicus 58245 R-RNO-6788798 https://reactome.org/PathwayBrowser/#/R-RNO-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 58245 R-RNO-6788810 https://reactome.org/PathwayBrowser/#/R-RNO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 58245 R-RNO-74207 https://reactome.org/PathwayBrowser/#/R-RNO-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Rattus norvegicus 58245 R-RNO-74220 https://reactome.org/PathwayBrowser/#/R-RNO-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Rattus norvegicus 58245 R-SCE-109624 https://reactome.org/PathwayBrowser/#/R-SCE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Saccharomyces cerevisiae 58245 R-SCE-111215 https://reactome.org/PathwayBrowser/#/R-SCE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Saccharomyces cerevisiae 58245 R-SCE-6788798 https://reactome.org/PathwayBrowser/#/R-SCE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 58245 R-SCE-6788810 https://reactome.org/PathwayBrowser/#/R-SCE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 58245 R-SPO-109624 https://reactome.org/PathwayBrowser/#/R-SPO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Schizosaccharomyces pombe 58245 R-SPO-111215 https://reactome.org/PathwayBrowser/#/R-SPO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Schizosaccharomyces pombe 58245 R-SPO-6788810 https://reactome.org/PathwayBrowser/#/R-SPO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Schizosaccharomyces pombe 58245 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 58245 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 58245 R-SSC-109624 https://reactome.org/PathwayBrowser/#/R-SSC-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Sus scrofa 58245 R-SSC-110137 https://reactome.org/PathwayBrowser/#/R-SSC-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Sus scrofa 58245 R-SSC-110138 https://reactome.org/PathwayBrowser/#/R-SSC-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 58245 R-SSC-110141 https://reactome.org/PathwayBrowser/#/R-SSC-110141 (d)ADP + ADP <=> (d)AMP + ATP (AK1) IEA Sus scrofa 58245 R-SSC-111215 https://reactome.org/PathwayBrowser/#/R-SSC-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Sus scrofa 58245 R-SSC-6788798 https://reactome.org/PathwayBrowser/#/R-SSC-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 58245 R-SSC-6788810 https://reactome.org/PathwayBrowser/#/R-SSC-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 58245 R-SSC-74207 https://reactome.org/PathwayBrowser/#/R-SSC-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Sus scrofa 58245 R-SSC-74220 https://reactome.org/PathwayBrowser/#/R-SSC-74220 (d)AMP + ATP <=> (d)ADP + ADP (AK1) IEA Sus scrofa 58245 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 58245 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 58245 R-XTR-109624 https://reactome.org/PathwayBrowser/#/R-XTR-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Xenopus tropicalis 58245 R-XTR-109671 https://reactome.org/PathwayBrowser/#/R-XTR-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Xenopus tropicalis 58245 R-XTR-110137 https://reactome.org/PathwayBrowser/#/R-XTR-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Xenopus tropicalis 58245 R-XTR-110138 https://reactome.org/PathwayBrowser/#/R-XTR-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 58245 R-XTR-111215 https://reactome.org/PathwayBrowser/#/R-XTR-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Xenopus tropicalis 58245 R-XTR-6788798 https://reactome.org/PathwayBrowser/#/R-XTR-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 58245 R-XTR-6788810 https://reactome.org/PathwayBrowser/#/R-XTR-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 58245 R-XTR-74207 https://reactome.org/PathwayBrowser/#/R-XTR-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Xenopus tropicalis 58251 R-BTA-1614654 https://reactome.org/PathwayBrowser/#/R-BTA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Bos taurus 58251 R-BTA-6797653 https://reactome.org/PathwayBrowser/#/R-BTA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Bos taurus 58251 R-CEL-6797653 https://reactome.org/PathwayBrowser/#/R-CEL-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Caenorhabditis elegans 58251 R-CFA-1614654 https://reactome.org/PathwayBrowser/#/R-CFA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Canis familiaris 58251 R-CFA-6797653 https://reactome.org/PathwayBrowser/#/R-CFA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Canis familiaris 58251 R-DRE-1614654 https://reactome.org/PathwayBrowser/#/R-DRE-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Danio rerio 58251 R-GGA-1614654 https://reactome.org/PathwayBrowser/#/R-GGA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Gallus gallus 58251 R-GGA-6797653 https://reactome.org/PathwayBrowser/#/R-GGA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Gallus gallus 58251 R-HSA-1614654 https://reactome.org/PathwayBrowser/#/R-HSA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY TAS Homo sapiens 58251 R-HSA-6797653 https://reactome.org/PathwayBrowser/#/R-HSA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC TAS Homo sapiens 58251 R-HSA-6797962 https://reactome.org/PathwayBrowser/#/R-HSA-6797962 DMGLY translocates from cytosol to mitochondrial matrix TAS Homo sapiens 58251 R-MMU-1614654 https://reactome.org/PathwayBrowser/#/R-MMU-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Mus musculus 58251 R-MMU-6797653 https://reactome.org/PathwayBrowser/#/R-MMU-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Mus musculus 58251 R-RNO-1614654 https://reactome.org/PathwayBrowser/#/R-RNO-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Rattus norvegicus 58251 R-RNO-6797653 https://reactome.org/PathwayBrowser/#/R-RNO-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Rattus norvegicus 58251 R-SSC-1614654 https://reactome.org/PathwayBrowser/#/R-SSC-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Sus scrofa 58251 R-SSC-6797653 https://reactome.org/PathwayBrowser/#/R-SSC-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Sus scrofa 58251 R-XTR-1614654 https://reactome.org/PathwayBrowser/#/R-XTR-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY IEA Xenopus tropicalis 58266 R-BTA-209828 https://reactome.org/PathwayBrowser/#/R-BTA-209828 Tryptophan is hydroxylated IEA Bos taurus 58266 R-BTA-209859 https://reactome.org/PathwayBrowser/#/R-BTA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Bos taurus 58266 R-CEL-209828 https://reactome.org/PathwayBrowser/#/R-CEL-209828 Tryptophan is hydroxylated IEA Caenorhabditis elegans 58266 R-CEL-209859 https://reactome.org/PathwayBrowser/#/R-CEL-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Caenorhabditis elegans 58266 R-CFA-209828 https://reactome.org/PathwayBrowser/#/R-CFA-209828 Tryptophan is hydroxylated IEA Canis familiaris 58266 R-CFA-209859 https://reactome.org/PathwayBrowser/#/R-CFA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Canis familiaris 58266 R-DDI-209828 https://reactome.org/PathwayBrowser/#/R-DDI-209828 Tryptophan is hydroxylated IEA Dictyostelium discoideum 58266 R-DME-209828 https://reactome.org/PathwayBrowser/#/R-DME-209828 Tryptophan is hydroxylated IEA Drosophila melanogaster 58266 R-DME-209859 https://reactome.org/PathwayBrowser/#/R-DME-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Drosophila melanogaster 58266 R-DRE-209828 https://reactome.org/PathwayBrowser/#/R-DRE-209828 Tryptophan is hydroxylated IEA Danio rerio 58266 R-DRE-209859 https://reactome.org/PathwayBrowser/#/R-DRE-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Danio rerio 58266 R-GGA-209828 https://reactome.org/PathwayBrowser/#/R-GGA-209828 Tryptophan is hydroxylated IEA Gallus gallus 58266 R-GGA-209859 https://reactome.org/PathwayBrowser/#/R-GGA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Gallus gallus 58266 R-HSA-209828 https://reactome.org/PathwayBrowser/#/R-HSA-209828 Tryptophan is hydroxylated TAS Homo sapiens 58266 R-HSA-209859 https://reactome.org/PathwayBrowser/#/R-HSA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin TAS Homo sapiens 58266 R-MMU-209828 https://reactome.org/PathwayBrowser/#/R-MMU-209828 Tryptophan is hydroxylated IEA Mus musculus 58266 R-MMU-209859 https://reactome.org/PathwayBrowser/#/R-MMU-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Mus musculus 58266 R-RNO-209828 https://reactome.org/PathwayBrowser/#/R-RNO-209828 Tryptophan is hydroxylated IEA Rattus norvegicus 58266 R-RNO-209859 https://reactome.org/PathwayBrowser/#/R-RNO-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Rattus norvegicus 58266 R-SSC-209828 https://reactome.org/PathwayBrowser/#/R-SSC-209828 Tryptophan is hydroxylated IEA Sus scrofa 58266 R-SSC-209859 https://reactome.org/PathwayBrowser/#/R-SSC-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Sus scrofa 58266 R-XTR-209859 https://reactome.org/PathwayBrowser/#/R-XTR-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin IEA Xenopus tropicalis 58272 R-BTA-6799495 https://reactome.org/PathwayBrowser/#/R-BTA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Bos taurus 58272 R-BTA-70486 https://reactome.org/PathwayBrowser/#/R-BTA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Bos taurus 58272 R-BTA-71445 https://reactome.org/PathwayBrowser/#/R-BTA-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Bos taurus 58272 R-BTA-71654 https://reactome.org/PathwayBrowser/#/R-BTA-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Bos taurus 58272 R-BTA-71850 https://reactome.org/PathwayBrowser/#/R-BTA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Bos taurus 58272 R-BTA-8955760 https://reactome.org/PathwayBrowser/#/R-BTA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Bos taurus 58272 R-BTA-977348 https://reactome.org/PathwayBrowser/#/R-BTA-977348 PHGDH tetramer dehydrogenates 3PG IEA Bos taurus 58272 R-CEL-6799495 https://reactome.org/PathwayBrowser/#/R-CEL-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Caenorhabditis elegans 58272 R-CEL-70486 https://reactome.org/PathwayBrowser/#/R-CEL-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Caenorhabditis elegans 58272 R-CEL-71850 https://reactome.org/PathwayBrowser/#/R-CEL-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Caenorhabditis elegans 58272 R-CEL-8955760 https://reactome.org/PathwayBrowser/#/R-CEL-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Caenorhabditis elegans 58272 R-CEL-977348 https://reactome.org/PathwayBrowser/#/R-CEL-977348 PHGDH tetramer dehydrogenates 3PG IEA Caenorhabditis elegans 58272 R-CFA-6799495 https://reactome.org/PathwayBrowser/#/R-CFA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Canis familiaris 58272 R-CFA-70486 https://reactome.org/PathwayBrowser/#/R-CFA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Canis familiaris 58272 R-CFA-71445 https://reactome.org/PathwayBrowser/#/R-CFA-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Canis familiaris 58272 R-CFA-71654 https://reactome.org/PathwayBrowser/#/R-CFA-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Canis familiaris 58272 R-CFA-71850 https://reactome.org/PathwayBrowser/#/R-CFA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Canis familiaris 58272 R-CFA-8955760 https://reactome.org/PathwayBrowser/#/R-CFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Canis familiaris 58272 R-CFA-977348 https://reactome.org/PathwayBrowser/#/R-CFA-977348 PHGDH tetramer dehydrogenates 3PG IEA Canis familiaris 58272 R-DDI-70486 https://reactome.org/PathwayBrowser/#/R-DDI-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Dictyostelium discoideum 58272 R-DDI-71445 https://reactome.org/PathwayBrowser/#/R-DDI-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Dictyostelium discoideum 58272 R-DDI-71654 https://reactome.org/PathwayBrowser/#/R-DDI-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Dictyostelium discoideum 58272 R-DDI-71850 https://reactome.org/PathwayBrowser/#/R-DDI-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Dictyostelium discoideum 58272 R-DDI-8955760 https://reactome.org/PathwayBrowser/#/R-DDI-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Dictyostelium discoideum 58272 R-DME-6799495 https://reactome.org/PathwayBrowser/#/R-DME-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Drosophila melanogaster 58272 R-DME-70486 https://reactome.org/PathwayBrowser/#/R-DME-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Drosophila melanogaster 58272 R-DME-71445 https://reactome.org/PathwayBrowser/#/R-DME-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Drosophila melanogaster 58272 R-DME-71654 https://reactome.org/PathwayBrowser/#/R-DME-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Drosophila melanogaster 58272 R-DME-71850 https://reactome.org/PathwayBrowser/#/R-DME-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Drosophila melanogaster 58272 R-DME-8955760 https://reactome.org/PathwayBrowser/#/R-DME-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Drosophila melanogaster 58272 R-DME-977348 https://reactome.org/PathwayBrowser/#/R-DME-977348 PHGDH tetramer dehydrogenates 3PG IEA Drosophila melanogaster 58272 R-DRE-6799495 https://reactome.org/PathwayBrowser/#/R-DRE-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Danio rerio 58272 R-DRE-70486 https://reactome.org/PathwayBrowser/#/R-DRE-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Danio rerio 58272 R-DRE-71445 https://reactome.org/PathwayBrowser/#/R-DRE-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Danio rerio 58272 R-DRE-71654 https://reactome.org/PathwayBrowser/#/R-DRE-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Danio rerio 58272 R-DRE-71850 https://reactome.org/PathwayBrowser/#/R-DRE-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Danio rerio 58272 R-DRE-8955760 https://reactome.org/PathwayBrowser/#/R-DRE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Danio rerio 58272 R-GGA-352994 https://reactome.org/PathwayBrowser/#/R-GGA-352994 3-phosphoglycerate <=> 2-phosphoglycerate TAS Gallus gallus 58272 R-GGA-353014 https://reactome.org/PathwayBrowser/#/R-GGA-353014 2-phosphoglycerate <=> 3-phosphoglycerate TAS Gallus gallus 58272 R-GGA-353023 https://reactome.org/PathwayBrowser/#/R-GGA-353023 3-phosphoglycerate + ATP <=> 1,3-bisphosphoglycerate + ADP TAS Gallus gallus 58272 R-GGA-353039 https://reactome.org/PathwayBrowser/#/R-GGA-353039 1,3-bisphosphoglycerate + ADP <=> 3-phosphoglycerate + ATP TAS Gallus gallus 58272 R-GGA-6799495 https://reactome.org/PathwayBrowser/#/R-GGA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Gallus gallus 58272 R-GGA-70486 https://reactome.org/PathwayBrowser/#/R-GGA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Gallus gallus 58272 R-GGA-71445 https://reactome.org/PathwayBrowser/#/R-GGA-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Gallus gallus 58272 R-GGA-71654 https://reactome.org/PathwayBrowser/#/R-GGA-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Gallus gallus 58272 R-GGA-71850 https://reactome.org/PathwayBrowser/#/R-GGA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Gallus gallus 58272 R-GGA-8955760 https://reactome.org/PathwayBrowser/#/R-GGA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Gallus gallus 58272 R-HSA-6799495 https://reactome.org/PathwayBrowser/#/R-HSA-6799495 GLYCTK phosphorylates DGA to 3PDGA TAS Homo sapiens 58272 R-HSA-70486 https://reactome.org/PathwayBrowser/#/R-HSA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG TAS Homo sapiens 58272 R-HSA-71445 https://reactome.org/PathwayBrowser/#/R-HSA-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG TAS Homo sapiens 58272 R-HSA-71654 https://reactome.org/PathwayBrowser/#/R-HSA-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate TAS Homo sapiens 58272 R-HSA-71850 https://reactome.org/PathwayBrowser/#/R-HSA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP TAS Homo sapiens 58272 R-HSA-8955760 https://reactome.org/PathwayBrowser/#/R-HSA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP TAS Homo sapiens 58272 R-HSA-8955794 https://reactome.org/PathwayBrowser/#/R-HSA-8955794 PGP:Mg2+ dimer hydrolyses 3PG to glycerol IEA Homo sapiens 58272 R-HSA-977348 https://reactome.org/PathwayBrowser/#/R-HSA-977348 PHGDH tetramer dehydrogenates 3PG TAS Homo sapiens 58272 R-MMU-6799495 https://reactome.org/PathwayBrowser/#/R-MMU-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Mus musculus 58272 R-MMU-70486 https://reactome.org/PathwayBrowser/#/R-MMU-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Mus musculus 58272 R-MMU-71445 https://reactome.org/PathwayBrowser/#/R-MMU-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Mus musculus 58272 R-MMU-71654 https://reactome.org/PathwayBrowser/#/R-MMU-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Mus musculus 58272 R-MMU-71850 https://reactome.org/PathwayBrowser/#/R-MMU-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Mus musculus 58272 R-MMU-8955760 https://reactome.org/PathwayBrowser/#/R-MMU-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Mus musculus 58272 R-MMU-977348 https://reactome.org/PathwayBrowser/#/R-MMU-977348 PHGDH tetramer dehydrogenates 3PG IEA Mus musculus 58272 R-PFA-70486 https://reactome.org/PathwayBrowser/#/R-PFA-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Plasmodium falciparum 58272 R-PFA-71445 https://reactome.org/PathwayBrowser/#/R-PFA-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Plasmodium falciparum 58272 R-PFA-71654 https://reactome.org/PathwayBrowser/#/R-PFA-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Plasmodium falciparum 58272 R-PFA-71850 https://reactome.org/PathwayBrowser/#/R-PFA-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Plasmodium falciparum 58272 R-PFA-8955760 https://reactome.org/PathwayBrowser/#/R-PFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Plasmodium falciparum 58272 R-RNO-6799495 https://reactome.org/PathwayBrowser/#/R-RNO-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Rattus norvegicus 58272 R-RNO-70486 https://reactome.org/PathwayBrowser/#/R-RNO-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Rattus norvegicus 58272 R-RNO-71445 https://reactome.org/PathwayBrowser/#/R-RNO-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Rattus norvegicus 58272 R-RNO-71654 https://reactome.org/PathwayBrowser/#/R-RNO-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Rattus norvegicus 58272 R-RNO-71850 https://reactome.org/PathwayBrowser/#/R-RNO-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Rattus norvegicus 58272 R-RNO-8955760 https://reactome.org/PathwayBrowser/#/R-RNO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Rattus norvegicus 58272 R-RNO-977348 https://reactome.org/PathwayBrowser/#/R-RNO-977348 PHGDH tetramer dehydrogenates 3PG IEA Rattus norvegicus 58272 R-SCE-70486 https://reactome.org/PathwayBrowser/#/R-SCE-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Saccharomyces cerevisiae 58272 R-SCE-71850 https://reactome.org/PathwayBrowser/#/R-SCE-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Saccharomyces cerevisiae 58272 R-SCE-8955760 https://reactome.org/PathwayBrowser/#/R-SCE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Saccharomyces cerevisiae 58272 R-SPO-70486 https://reactome.org/PathwayBrowser/#/R-SPO-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Schizosaccharomyces pombe 58272 R-SPO-71445 https://reactome.org/PathwayBrowser/#/R-SPO-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Schizosaccharomyces pombe 58272 R-SPO-71654 https://reactome.org/PathwayBrowser/#/R-SPO-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Schizosaccharomyces pombe 58272 R-SPO-71850 https://reactome.org/PathwayBrowser/#/R-SPO-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Schizosaccharomyces pombe 58272 R-SPO-8955760 https://reactome.org/PathwayBrowser/#/R-SPO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Schizosaccharomyces pombe 58272 R-SSC-6799495 https://reactome.org/PathwayBrowser/#/R-SSC-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Sus scrofa 58272 R-SSC-70486 https://reactome.org/PathwayBrowser/#/R-SSC-70486 PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG IEA Sus scrofa 58272 R-SSC-71445 https://reactome.org/PathwayBrowser/#/R-SSC-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Sus scrofa 58272 R-SSC-71654 https://reactome.org/PathwayBrowser/#/R-SSC-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Sus scrofa 58272 R-SSC-71850 https://reactome.org/PathwayBrowser/#/R-SSC-71850 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP IEA Sus scrofa 58272 R-SSC-8955760 https://reactome.org/PathwayBrowser/#/R-SSC-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Sus scrofa 58272 R-SSC-977348 https://reactome.org/PathwayBrowser/#/R-SSC-977348 PHGDH tetramer dehydrogenates 3PG IEA Sus scrofa 58272 R-XTR-71445 https://reactome.org/PathwayBrowser/#/R-XTR-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Xenopus tropicalis 58272 R-XTR-71654 https://reactome.org/PathwayBrowser/#/R-XTR-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Xenopus tropicalis 58272 R-XTR-8955760 https://reactome.org/PathwayBrowser/#/R-XTR-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Xenopus tropicalis 58272 R-XTR-977348 https://reactome.org/PathwayBrowser/#/R-XTR-977348 PHGDH tetramer dehydrogenates 3PG IEA Xenopus tropicalis 58280 R-BTA-2509816 https://reactome.org/PathwayBrowser/#/R-BTA-2509816 NUDT16 hydrolyses IDP to IMP IEA Bos taurus 58280 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 58280 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 58280 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 58280 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 58280 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58280 R-CFA-2509816 https://reactome.org/PathwayBrowser/#/R-CFA-2509816 NUDT16 hydrolyses IDP to IMP IEA Canis familiaris 58280 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58280 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58280 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58280 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58280 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 58280 R-DRE-2509816 https://reactome.org/PathwayBrowser/#/R-DRE-2509816 NUDT16 hydrolyses IDP to IMP IEA Danio rerio 58280 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 58280 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 58280 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 58280 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 58280 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58280 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58280 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58280 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58280 R-HSA-2509816 https://reactome.org/PathwayBrowser/#/R-HSA-2509816 NUDT16 hydrolyses IDP to IMP TAS Homo sapiens 58280 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58280 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58280 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58280 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58280 R-MMU-2509816 https://reactome.org/PathwayBrowser/#/R-MMU-2509816 NUDT16 hydrolyses IDP to IMP IEA Mus musculus 58280 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 58280 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 58280 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 58280 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 58280 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 58280 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58280 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 58280 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58280 R-RNO-2509816 https://reactome.org/PathwayBrowser/#/R-RNO-2509816 NUDT16 hydrolyses IDP to IMP IEA Rattus norvegicus 58280 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58280 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58280 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58280 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58280 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58280 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58280 R-SSC-2509816 https://reactome.org/PathwayBrowser/#/R-SSC-2509816 NUDT16 hydrolyses IDP to IMP IEA Sus scrofa 58280 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58280 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58280 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58280 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58280 R-XTR-2509816 https://reactome.org/PathwayBrowser/#/R-XTR-2509816 NUDT16 hydrolyses IDP to IMP IEA Xenopus tropicalis 58280 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58280 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58280 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58280 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58289 R-BTA-70494 https://reactome.org/PathwayBrowser/#/R-BTA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Bos taurus 58289 R-BTA-71445 https://reactome.org/PathwayBrowser/#/R-BTA-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Bos taurus 58289 R-BTA-71654 https://reactome.org/PathwayBrowser/#/R-BTA-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Bos taurus 58289 R-BTA-71660 https://reactome.org/PathwayBrowser/#/R-BTA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Bos taurus 58289 R-CEL-70494 https://reactome.org/PathwayBrowser/#/R-CEL-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Caenorhabditis elegans 58289 R-CEL-71660 https://reactome.org/PathwayBrowser/#/R-CEL-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Caenorhabditis elegans 58289 R-CFA-70494 https://reactome.org/PathwayBrowser/#/R-CFA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Canis familiaris 58289 R-CFA-71445 https://reactome.org/PathwayBrowser/#/R-CFA-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Canis familiaris 58289 R-CFA-71654 https://reactome.org/PathwayBrowser/#/R-CFA-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Canis familiaris 58289 R-CFA-71660 https://reactome.org/PathwayBrowser/#/R-CFA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Canis familiaris 58289 R-DDI-70494 https://reactome.org/PathwayBrowser/#/R-DDI-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Dictyostelium discoideum 58289 R-DDI-71445 https://reactome.org/PathwayBrowser/#/R-DDI-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Dictyostelium discoideum 58289 R-DDI-71654 https://reactome.org/PathwayBrowser/#/R-DDI-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Dictyostelium discoideum 58289 R-DDI-71660 https://reactome.org/PathwayBrowser/#/R-DDI-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Dictyostelium discoideum 58289 R-DME-70494 https://reactome.org/PathwayBrowser/#/R-DME-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Drosophila melanogaster 58289 R-DME-71445 https://reactome.org/PathwayBrowser/#/R-DME-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Drosophila melanogaster 58289 R-DME-71654 https://reactome.org/PathwayBrowser/#/R-DME-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Drosophila melanogaster 58289 R-DME-71660 https://reactome.org/PathwayBrowser/#/R-DME-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Drosophila melanogaster 58289 R-DRE-70494 https://reactome.org/PathwayBrowser/#/R-DRE-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Danio rerio 58289 R-DRE-71445 https://reactome.org/PathwayBrowser/#/R-DRE-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Danio rerio 58289 R-DRE-71654 https://reactome.org/PathwayBrowser/#/R-DRE-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Danio rerio 58289 R-DRE-71660 https://reactome.org/PathwayBrowser/#/R-DRE-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Danio rerio 58289 R-GGA-352981 https://reactome.org/PathwayBrowser/#/R-GGA-352981 phosphoenolpyruvate + H2O <=> 2-phosphoglycerate TAS Gallus gallus 58289 R-GGA-352994 https://reactome.org/PathwayBrowser/#/R-GGA-352994 3-phosphoglycerate <=> 2-phosphoglycerate TAS Gallus gallus 58289 R-GGA-353014 https://reactome.org/PathwayBrowser/#/R-GGA-353014 2-phosphoglycerate <=> 3-phosphoglycerate TAS Gallus gallus 58289 R-GGA-353044 https://reactome.org/PathwayBrowser/#/R-GGA-353044 2-phosphoglycerate <=> phosphoenolpyruvate + H2O TAS Gallus gallus 58289 R-GGA-70494 https://reactome.org/PathwayBrowser/#/R-GGA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Gallus gallus 58289 R-GGA-71445 https://reactome.org/PathwayBrowser/#/R-GGA-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Gallus gallus 58289 R-GGA-71654 https://reactome.org/PathwayBrowser/#/R-GGA-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Gallus gallus 58289 R-GGA-71660 https://reactome.org/PathwayBrowser/#/R-GGA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Gallus gallus 58289 R-HSA-70494 https://reactome.org/PathwayBrowser/#/R-HSA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG TAS Homo sapiens 58289 R-HSA-71445 https://reactome.org/PathwayBrowser/#/R-HSA-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG TAS Homo sapiens 58289 R-HSA-71654 https://reactome.org/PathwayBrowser/#/R-HSA-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate TAS Homo sapiens 58289 R-HSA-71660 https://reactome.org/PathwayBrowser/#/R-HSA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O TAS Homo sapiens 58289 R-MMU-70494 https://reactome.org/PathwayBrowser/#/R-MMU-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Mus musculus 58289 R-MMU-71445 https://reactome.org/PathwayBrowser/#/R-MMU-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Mus musculus 58289 R-MMU-71654 https://reactome.org/PathwayBrowser/#/R-MMU-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Mus musculus 58289 R-MMU-71660 https://reactome.org/PathwayBrowser/#/R-MMU-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Mus musculus 58289 R-PFA-70494 https://reactome.org/PathwayBrowser/#/R-PFA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Plasmodium falciparum 58289 R-PFA-71445 https://reactome.org/PathwayBrowser/#/R-PFA-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Plasmodium falciparum 58289 R-PFA-71654 https://reactome.org/PathwayBrowser/#/R-PFA-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Plasmodium falciparum 58289 R-PFA-71660 https://reactome.org/PathwayBrowser/#/R-PFA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Plasmodium falciparum 58289 R-RNO-70494 https://reactome.org/PathwayBrowser/#/R-RNO-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Rattus norvegicus 58289 R-RNO-71445 https://reactome.org/PathwayBrowser/#/R-RNO-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Rattus norvegicus 58289 R-RNO-71654 https://reactome.org/PathwayBrowser/#/R-RNO-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Rattus norvegicus 58289 R-RNO-71660 https://reactome.org/PathwayBrowser/#/R-RNO-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Rattus norvegicus 58289 R-SCE-70494 https://reactome.org/PathwayBrowser/#/R-SCE-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Saccharomyces cerevisiae 58289 R-SCE-71660 https://reactome.org/PathwayBrowser/#/R-SCE-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Saccharomyces cerevisiae 58289 R-SPO-70494 https://reactome.org/PathwayBrowser/#/R-SPO-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Schizosaccharomyces pombe 58289 R-SPO-71445 https://reactome.org/PathwayBrowser/#/R-SPO-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Schizosaccharomyces pombe 58289 R-SPO-71654 https://reactome.org/PathwayBrowser/#/R-SPO-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Schizosaccharomyces pombe 58289 R-SPO-71660 https://reactome.org/PathwayBrowser/#/R-SPO-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Schizosaccharomyces pombe 58289 R-SSC-70494 https://reactome.org/PathwayBrowser/#/R-SSC-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Sus scrofa 58289 R-SSC-71445 https://reactome.org/PathwayBrowser/#/R-SSC-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Sus scrofa 58289 R-SSC-71654 https://reactome.org/PathwayBrowser/#/R-SSC-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Sus scrofa 58289 R-SSC-71660 https://reactome.org/PathwayBrowser/#/R-SSC-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Sus scrofa 58289 R-XTR-70494 https://reactome.org/PathwayBrowser/#/R-XTR-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Xenopus tropicalis 58289 R-XTR-71445 https://reactome.org/PathwayBrowser/#/R-XTR-71445 PGAM dimers (PGAM1,2) isomerise 2PG to 3PG IEA Xenopus tropicalis 58289 R-XTR-71654 https://reactome.org/PathwayBrowser/#/R-XTR-71654 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate IEA Xenopus tropicalis 58289 R-XTR-71660 https://reactome.org/PathwayBrowser/#/R-XTR-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Xenopus tropicalis 58297 R-BTA-111746 https://reactome.org/PathwayBrowser/#/R-BTA-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Bos taurus 58297 R-BTA-1655879 https://reactome.org/PathwayBrowser/#/R-BTA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Bos taurus 58297 R-BTA-198813 https://reactome.org/PathwayBrowser/#/R-BTA-198813 GSTO dimers reduce DeHA to AscH- IEA Bos taurus 58297 R-BTA-2161959 https://reactome.org/PathwayBrowser/#/R-BTA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Bos taurus 58297 R-BTA-2161999 https://reactome.org/PathwayBrowser/#/R-BTA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Bos taurus 58297 R-BTA-3323013 https://reactome.org/PathwayBrowser/#/R-BTA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 58297 R-BTA-3323079 https://reactome.org/PathwayBrowser/#/R-BTA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 58297 R-BTA-3341397 https://reactome.org/PathwayBrowser/#/R-BTA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 58297 R-BTA-3343700 https://reactome.org/PathwayBrowser/#/R-BTA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 58297 R-BTA-5696230 https://reactome.org/PathwayBrowser/#/R-BTA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Bos taurus 58297 R-BTA-6799695 https://reactome.org/PathwayBrowser/#/R-BTA-6799695 GPX5,6 reduce H2O2 to H2O IEA Bos taurus 58297 R-BTA-71676 https://reactome.org/PathwayBrowser/#/R-BTA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Bos taurus 58297 R-BTA-71682 https://reactome.org/PathwayBrowser/#/R-BTA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 58297 R-BTA-9018868 https://reactome.org/PathwayBrowser/#/R-BTA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Bos taurus 58297 R-BTA-9018895 https://reactome.org/PathwayBrowser/#/R-BTA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Bos taurus 58297 R-BTA-9020271 https://reactome.org/PathwayBrowser/#/R-BTA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Bos taurus 58297 R-BTA-9020273 https://reactome.org/PathwayBrowser/#/R-BTA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Bos taurus 58297 R-CEL-111746 https://reactome.org/PathwayBrowser/#/R-CEL-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Caenorhabditis elegans 58297 R-CEL-198813 https://reactome.org/PathwayBrowser/#/R-CEL-198813 GSTO dimers reduce DeHA to AscH- IEA Caenorhabditis elegans 58297 R-CEL-2161959 https://reactome.org/PathwayBrowser/#/R-CEL-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Caenorhabditis elegans 58297 R-CEL-2161999 https://reactome.org/PathwayBrowser/#/R-CEL-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Caenorhabditis elegans 58297 R-CEL-3323079 https://reactome.org/PathwayBrowser/#/R-CEL-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 58297 R-CEL-3341397 https://reactome.org/PathwayBrowser/#/R-CEL-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Caenorhabditis elegans 58297 R-CEL-3343700 https://reactome.org/PathwayBrowser/#/R-CEL-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Caenorhabditis elegans 58297 R-CEL-5696230 https://reactome.org/PathwayBrowser/#/R-CEL-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Caenorhabditis elegans 58297 R-CEL-6799695 https://reactome.org/PathwayBrowser/#/R-CEL-6799695 GPX5,6 reduce H2O2 to H2O IEA Caenorhabditis elegans 58297 R-CEL-71682 https://reactome.org/PathwayBrowser/#/R-CEL-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 58297 R-CEL-9018868 https://reactome.org/PathwayBrowser/#/R-CEL-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Caenorhabditis elegans 58297 R-CEL-9018895 https://reactome.org/PathwayBrowser/#/R-CEL-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Caenorhabditis elegans 58297 R-CEL-9020271 https://reactome.org/PathwayBrowser/#/R-CEL-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Caenorhabditis elegans 58297 R-CEL-9020273 https://reactome.org/PathwayBrowser/#/R-CEL-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Caenorhabditis elegans 58297 R-CFA-111746 https://reactome.org/PathwayBrowser/#/R-CFA-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Canis familiaris 58297 R-CFA-1655879 https://reactome.org/PathwayBrowser/#/R-CFA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Canis familiaris 58297 R-CFA-198813 https://reactome.org/PathwayBrowser/#/R-CFA-198813 GSTO dimers reduce DeHA to AscH- IEA Canis familiaris 58297 R-CFA-2161791 https://reactome.org/PathwayBrowser/#/R-CFA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Canis familiaris 58297 R-CFA-2161959 https://reactome.org/PathwayBrowser/#/R-CFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Canis familiaris 58297 R-CFA-2161999 https://reactome.org/PathwayBrowser/#/R-CFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Canis familiaris 58297 R-CFA-3323013 https://reactome.org/PathwayBrowser/#/R-CFA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 58297 R-CFA-3323079 https://reactome.org/PathwayBrowser/#/R-CFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 58297 R-CFA-3341277 https://reactome.org/PathwayBrowser/#/R-CFA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 58297 R-CFA-3343700 https://reactome.org/PathwayBrowser/#/R-CFA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 58297 R-CFA-5696230 https://reactome.org/PathwayBrowser/#/R-CFA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Canis familiaris 58297 R-CFA-6799695 https://reactome.org/PathwayBrowser/#/R-CFA-6799695 GPX5,6 reduce H2O2 to H2O IEA Canis familiaris 58297 R-CFA-71676 https://reactome.org/PathwayBrowser/#/R-CFA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Canis familiaris 58297 R-CFA-71682 https://reactome.org/PathwayBrowser/#/R-CFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 58297 R-CFA-9018868 https://reactome.org/PathwayBrowser/#/R-CFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Canis familiaris 58297 R-CFA-9018895 https://reactome.org/PathwayBrowser/#/R-CFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Canis familiaris 58297 R-CFA-9020271 https://reactome.org/PathwayBrowser/#/R-CFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Canis familiaris 58297 R-CFA-9020273 https://reactome.org/PathwayBrowser/#/R-CFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Canis familiaris 58297 R-DDI-3323079 https://reactome.org/PathwayBrowser/#/R-DDI-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 58297 R-DDI-3343700 https://reactome.org/PathwayBrowser/#/R-DDI-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Dictyostelium discoideum 58297 R-DDI-71682 https://reactome.org/PathwayBrowser/#/R-DDI-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 58297 R-DME-198813 https://reactome.org/PathwayBrowser/#/R-DME-198813 GSTO dimers reduce DeHA to AscH- IEA Drosophila melanogaster 58297 R-DME-5696230 https://reactome.org/PathwayBrowser/#/R-DME-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Drosophila melanogaster 58297 R-DRE-111746 https://reactome.org/PathwayBrowser/#/R-DRE-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Danio rerio 58297 R-DRE-198813 https://reactome.org/PathwayBrowser/#/R-DRE-198813 GSTO dimers reduce DeHA to AscH- IEA Danio rerio 58297 R-DRE-3343700 https://reactome.org/PathwayBrowser/#/R-DRE-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Danio rerio 58297 R-DRE-5696230 https://reactome.org/PathwayBrowser/#/R-DRE-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Danio rerio 58297 R-DRE-6799695 https://reactome.org/PathwayBrowser/#/R-DRE-6799695 GPX5,6 reduce H2O2 to H2O IEA Danio rerio 58297 R-GGA-111746 https://reactome.org/PathwayBrowser/#/R-GGA-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Gallus gallus 58297 R-GGA-198813 https://reactome.org/PathwayBrowser/#/R-GGA-198813 GSTO dimers reduce DeHA to AscH- IEA Gallus gallus 58297 R-GGA-2161959 https://reactome.org/PathwayBrowser/#/R-GGA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Gallus gallus 58297 R-GGA-2161999 https://reactome.org/PathwayBrowser/#/R-GGA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Gallus gallus 58297 R-GGA-3323079 https://reactome.org/PathwayBrowser/#/R-GGA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 58297 R-GGA-3341277 https://reactome.org/PathwayBrowser/#/R-GGA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Gallus gallus 58297 R-GGA-3341397 https://reactome.org/PathwayBrowser/#/R-GGA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Gallus gallus 58297 R-GGA-5696230 https://reactome.org/PathwayBrowser/#/R-GGA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Gallus gallus 58297 R-GGA-71682 https://reactome.org/PathwayBrowser/#/R-GGA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 58297 R-GGA-9018868 https://reactome.org/PathwayBrowser/#/R-GGA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Gallus gallus 58297 R-GGA-9018895 https://reactome.org/PathwayBrowser/#/R-GGA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Gallus gallus 58297 R-GGA-9020271 https://reactome.org/PathwayBrowser/#/R-GGA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Gallus gallus 58297 R-GGA-9020273 https://reactome.org/PathwayBrowser/#/R-GGA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Gallus gallus 58297 R-HSA-111746 https://reactome.org/PathwayBrowser/#/R-HSA-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) TAS Homo sapiens 58297 R-HSA-1655879 https://reactome.org/PathwayBrowser/#/R-HSA-1655879 Thiosulfate can transfer its sulfur atom to glutathione TAS Homo sapiens 58297 R-HSA-198813 https://reactome.org/PathwayBrowser/#/R-HSA-198813 GSTO dimers reduce DeHA to AscH- TAS Homo sapiens 58297 R-HSA-2161791 https://reactome.org/PathwayBrowser/#/R-HSA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 TAS Homo sapiens 58297 R-HSA-2161946 https://reactome.org/PathwayBrowser/#/R-HSA-2161946 5S-HpETE is reduced to 5S-HETE by GPX1/2/4 IEA Homo sapiens 58297 R-HSA-2161959 https://reactome.org/PathwayBrowser/#/R-HSA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 TAS Homo sapiens 58297 R-HSA-2161999 https://reactome.org/PathwayBrowser/#/R-HSA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 TAS Homo sapiens 58297 R-HSA-2408500 https://reactome.org/PathwayBrowser/#/R-HSA-2408500 GSSeH condenses with GSH to form H2Se and GSSG IEA Homo sapiens 58297 R-HSA-2408556 https://reactome.org/PathwayBrowser/#/R-HSA-2408556 SeO3(2-) combines with GSH to form GSSeSG and GSSG IEA Homo sapiens 58297 R-HSA-3323013 https://reactome.org/PathwayBrowser/#/R-HSA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 58297 R-HSA-3323079 https://reactome.org/PathwayBrowser/#/R-HSA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 58297 R-HSA-3341277 https://reactome.org/PathwayBrowser/#/R-HSA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 58297 R-HSA-3341397 https://reactome.org/PathwayBrowser/#/R-HSA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 58297 R-HSA-3343700 https://reactome.org/PathwayBrowser/#/R-HSA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 58297 R-HSA-5696230 https://reactome.org/PathwayBrowser/#/R-HSA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite TAS Homo sapiens 58297 R-HSA-6799695 https://reactome.org/PathwayBrowser/#/R-HSA-6799695 GPX5,6 reduce H2O2 to H2O TAS Homo sapiens 58297 R-HSA-71676 https://reactome.org/PathwayBrowser/#/R-HSA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O TAS Homo sapiens 58297 R-HSA-71682 https://reactome.org/PathwayBrowser/#/R-HSA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 58297 R-HSA-9018868 https://reactome.org/PathwayBrowser/#/R-HSA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE TAS Homo sapiens 58297 R-HSA-9018895 https://reactome.org/PathwayBrowser/#/R-HSA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE TAS Homo sapiens 58297 R-HSA-9020271 https://reactome.org/PathwayBrowser/#/R-HSA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA TAS Homo sapiens 58297 R-HSA-9020273 https://reactome.org/PathwayBrowser/#/R-HSA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA TAS Homo sapiens 58297 R-MMU-111746 https://reactome.org/PathwayBrowser/#/R-MMU-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Mus musculus 58297 R-MMU-1655879 https://reactome.org/PathwayBrowser/#/R-MMU-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Mus musculus 58297 R-MMU-198813 https://reactome.org/PathwayBrowser/#/R-MMU-198813 GSTO dimers reduce DeHA to AscH- IEA Mus musculus 58297 R-MMU-2161791 https://reactome.org/PathwayBrowser/#/R-MMU-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Mus musculus 58297 R-MMU-2161959 https://reactome.org/PathwayBrowser/#/R-MMU-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Mus musculus 58297 R-MMU-2161999 https://reactome.org/PathwayBrowser/#/R-MMU-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Mus musculus 58297 R-MMU-3323013 https://reactome.org/PathwayBrowser/#/R-MMU-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 58297 R-MMU-3323079 https://reactome.org/PathwayBrowser/#/R-MMU-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 58297 R-MMU-3341277 https://reactome.org/PathwayBrowser/#/R-MMU-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 58297 R-MMU-3341397 https://reactome.org/PathwayBrowser/#/R-MMU-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 58297 R-MMU-3343700 https://reactome.org/PathwayBrowser/#/R-MMU-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 58297 R-MMU-5696230 https://reactome.org/PathwayBrowser/#/R-MMU-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Mus musculus 58297 R-MMU-6799695 https://reactome.org/PathwayBrowser/#/R-MMU-6799695 GPX5,6 reduce H2O2 to H2O IEA Mus musculus 58297 R-MMU-71676 https://reactome.org/PathwayBrowser/#/R-MMU-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Mus musculus 58297 R-MMU-71682 https://reactome.org/PathwayBrowser/#/R-MMU-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 58297 R-MMU-9018868 https://reactome.org/PathwayBrowser/#/R-MMU-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Mus musculus 58297 R-MMU-9018895 https://reactome.org/PathwayBrowser/#/R-MMU-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Mus musculus 58297 R-MMU-9020271 https://reactome.org/PathwayBrowser/#/R-MMU-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Mus musculus 58297 R-MMU-9020273 https://reactome.org/PathwayBrowser/#/R-MMU-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Mus musculus 58297 R-OCU-2161896 https://reactome.org/PathwayBrowser/#/R-OCU-2161896 5S-HpETE is reduced to 5S-HETE by GPX1 TAS Oryctolagus cuniculus 58297 R-PFA-111746 https://reactome.org/PathwayBrowser/#/R-PFA-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Plasmodium falciparum 58297 R-PFA-2161959 https://reactome.org/PathwayBrowser/#/R-PFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Plasmodium falciparum 58297 R-PFA-2161999 https://reactome.org/PathwayBrowser/#/R-PFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Plasmodium falciparum 58297 R-PFA-3323079 https://reactome.org/PathwayBrowser/#/R-PFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 58297 R-PFA-3343700 https://reactome.org/PathwayBrowser/#/R-PFA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Plasmodium falciparum 58297 R-PFA-71682 https://reactome.org/PathwayBrowser/#/R-PFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 58297 R-PFA-9018868 https://reactome.org/PathwayBrowser/#/R-PFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Plasmodium falciparum 58297 R-PFA-9018895 https://reactome.org/PathwayBrowser/#/R-PFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Plasmodium falciparum 58297 R-PFA-9020271 https://reactome.org/PathwayBrowser/#/R-PFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Plasmodium falciparum 58297 R-PFA-9020273 https://reactome.org/PathwayBrowser/#/R-PFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Plasmodium falciparum 58297 R-RNO-111746 https://reactome.org/PathwayBrowser/#/R-RNO-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Rattus norvegicus 58297 R-RNO-1655879 https://reactome.org/PathwayBrowser/#/R-RNO-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Rattus norvegicus 58297 R-RNO-198813 https://reactome.org/PathwayBrowser/#/R-RNO-198813 GSTO dimers reduce DeHA to AscH- IEA Rattus norvegicus 58297 R-RNO-2161791 https://reactome.org/PathwayBrowser/#/R-RNO-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Rattus norvegicus 58297 R-RNO-2161959 https://reactome.org/PathwayBrowser/#/R-RNO-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Rattus norvegicus 58297 R-RNO-2161999 https://reactome.org/PathwayBrowser/#/R-RNO-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Rattus norvegicus 58297 R-RNO-2408520 https://reactome.org/PathwayBrowser/#/R-RNO-2408520 GSSeH condenses with GSH to form H2Se and GSSG TAS Rattus norvegicus 58297 R-RNO-2408553 https://reactome.org/PathwayBrowser/#/R-RNO-2408553 SeO3(2-) combines with GSH to form GSSeSG and GSSG TAS Rattus norvegicus 58297 R-RNO-3323013 https://reactome.org/PathwayBrowser/#/R-RNO-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 58297 R-RNO-3323079 https://reactome.org/PathwayBrowser/#/R-RNO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 58297 R-RNO-3341277 https://reactome.org/PathwayBrowser/#/R-RNO-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 58297 R-RNO-3341397 https://reactome.org/PathwayBrowser/#/R-RNO-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 58297 R-RNO-3343700 https://reactome.org/PathwayBrowser/#/R-RNO-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 58297 R-RNO-5696230 https://reactome.org/PathwayBrowser/#/R-RNO-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Rattus norvegicus 58297 R-RNO-6799695 https://reactome.org/PathwayBrowser/#/R-RNO-6799695 GPX5,6 reduce H2O2 to H2O IEA Rattus norvegicus 58297 R-RNO-71676 https://reactome.org/PathwayBrowser/#/R-RNO-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Rattus norvegicus 58297 R-RNO-71682 https://reactome.org/PathwayBrowser/#/R-RNO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 58297 R-RNO-9018868 https://reactome.org/PathwayBrowser/#/R-RNO-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Rattus norvegicus 58297 R-RNO-9018895 https://reactome.org/PathwayBrowser/#/R-RNO-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Rattus norvegicus 58297 R-RNO-9020271 https://reactome.org/PathwayBrowser/#/R-RNO-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Rattus norvegicus 58297 R-RNO-9020273 https://reactome.org/PathwayBrowser/#/R-RNO-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Rattus norvegicus 58297 R-SCE-3323079 https://reactome.org/PathwayBrowser/#/R-SCE-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 58297 R-SCE-71682 https://reactome.org/PathwayBrowser/#/R-SCE-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 58297 R-SPO-3323079 https://reactome.org/PathwayBrowser/#/R-SPO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 58297 R-SPO-71682 https://reactome.org/PathwayBrowser/#/R-SPO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 58297 R-SSC-111746 https://reactome.org/PathwayBrowser/#/R-SSC-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Sus scrofa 58297 R-SSC-1655879 https://reactome.org/PathwayBrowser/#/R-SSC-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Sus scrofa 58297 R-SSC-198813 https://reactome.org/PathwayBrowser/#/R-SSC-198813 GSTO dimers reduce DeHA to AscH- IEA Sus scrofa 58297 R-SSC-2161791 https://reactome.org/PathwayBrowser/#/R-SSC-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Sus scrofa 58297 R-SSC-2161959 https://reactome.org/PathwayBrowser/#/R-SSC-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Sus scrofa 58297 R-SSC-2161999 https://reactome.org/PathwayBrowser/#/R-SSC-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Sus scrofa 58297 R-SSC-3323013 https://reactome.org/PathwayBrowser/#/R-SSC-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 58297 R-SSC-3323079 https://reactome.org/PathwayBrowser/#/R-SSC-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 58297 R-SSC-3341277 https://reactome.org/PathwayBrowser/#/R-SSC-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 58297 R-SSC-3341397 https://reactome.org/PathwayBrowser/#/R-SSC-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 58297 R-SSC-3343700 https://reactome.org/PathwayBrowser/#/R-SSC-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 58297 R-SSC-5696230 https://reactome.org/PathwayBrowser/#/R-SSC-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Sus scrofa 58297 R-SSC-6799695 https://reactome.org/PathwayBrowser/#/R-SSC-6799695 GPX5,6 reduce H2O2 to H2O IEA Sus scrofa 58297 R-SSC-71676 https://reactome.org/PathwayBrowser/#/R-SSC-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Sus scrofa 58297 R-SSC-71682 https://reactome.org/PathwayBrowser/#/R-SSC-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 58297 R-SSC-9018868 https://reactome.org/PathwayBrowser/#/R-SSC-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Sus scrofa 58297 R-SSC-9018895 https://reactome.org/PathwayBrowser/#/R-SSC-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Sus scrofa 58297 R-SSC-9020271 https://reactome.org/PathwayBrowser/#/R-SSC-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Sus scrofa 58297 R-SSC-9020273 https://reactome.org/PathwayBrowser/#/R-SSC-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Sus scrofa 58297 R-XTR-111746 https://reactome.org/PathwayBrowser/#/R-XTR-111746 glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) IEA Xenopus tropicalis 58297 R-XTR-1655879 https://reactome.org/PathwayBrowser/#/R-XTR-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Xenopus tropicalis 58297 R-XTR-198813 https://reactome.org/PathwayBrowser/#/R-XTR-198813 GSTO dimers reduce DeHA to AscH- IEA Xenopus tropicalis 58297 R-XTR-3323079 https://reactome.org/PathwayBrowser/#/R-XTR-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 58297 R-XTR-3343700 https://reactome.org/PathwayBrowser/#/R-XTR-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Xenopus tropicalis 58297 R-XTR-5696230 https://reactome.org/PathwayBrowser/#/R-XTR-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Xenopus tropicalis 58297 R-XTR-71682 https://reactome.org/PathwayBrowser/#/R-XTR-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 58303 R-BTA-390427 https://reactome.org/PathwayBrowser/#/R-BTA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Bos taurus 58303 R-BTA-75879 https://reactome.org/PathwayBrowser/#/R-BTA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Bos taurus 58303 R-CEL-390427 https://reactome.org/PathwayBrowser/#/R-CEL-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Caenorhabditis elegans 58303 R-CEL-75879 https://reactome.org/PathwayBrowser/#/R-CEL-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Caenorhabditis elegans 58303 R-CFA-390427 https://reactome.org/PathwayBrowser/#/R-CFA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Canis familiaris 58303 R-CFA-75879 https://reactome.org/PathwayBrowser/#/R-CFA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Canis familiaris 58303 R-DME-390427 https://reactome.org/PathwayBrowser/#/R-DME-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Drosophila melanogaster 58303 R-DME-75879 https://reactome.org/PathwayBrowser/#/R-DME-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Drosophila melanogaster 58303 R-HSA-390427 https://reactome.org/PathwayBrowser/#/R-HSA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate TAS Homo sapiens 58303 R-HSA-75879 https://reactome.org/PathwayBrowser/#/R-HSA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH TAS Homo sapiens 58303 R-MMU-390427 https://reactome.org/PathwayBrowser/#/R-MMU-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Mus musculus 58303 R-MMU-75879 https://reactome.org/PathwayBrowser/#/R-MMU-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Mus musculus 58303 R-RNO-390427 https://reactome.org/PathwayBrowser/#/R-RNO-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Rattus norvegicus 58303 R-RNO-75879 https://reactome.org/PathwayBrowser/#/R-RNO-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Rattus norvegicus 58303 R-SSC-390427 https://reactome.org/PathwayBrowser/#/R-SSC-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Sus scrofa 58303 R-SSC-75879 https://reactome.org/PathwayBrowser/#/R-SSC-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Sus scrofa 58303 R-XTR-390427 https://reactome.org/PathwayBrowser/#/R-XTR-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Xenopus tropicalis 58303 R-XTR-75879 https://reactome.org/PathwayBrowser/#/R-XTR-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Xenopus tropicalis 58307 R-BTA-109341 https://reactome.org/PathwayBrowser/#/R-BTA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Bos taurus 58307 R-BTA-188467 https://reactome.org/PathwayBrowser/#/R-BTA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Bos taurus 58307 R-BTA-2395512 https://reactome.org/PathwayBrowser/#/R-BTA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Bos taurus 58307 R-BTA-2395517 https://reactome.org/PathwayBrowser/#/R-BTA-2395517 NADPH transfers electrons to FDXR IEA Bos taurus 58307 R-BTA-3159253 https://reactome.org/PathwayBrowser/#/R-BTA-3159253 MMAB adenosylates cob(I)alamin IEA Bos taurus 58307 R-BTA-5695980 https://reactome.org/PathwayBrowser/#/R-BTA-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Bos taurus 58307 R-BTA-5695989 https://reactome.org/PathwayBrowser/#/R-BTA-5695989 ACAD11 dehydrogenates BH-CoA IEA Bos taurus 58307 R-BTA-70670 https://reactome.org/PathwayBrowser/#/R-BTA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Bos taurus 58307 R-BTA-70745 https://reactome.org/PathwayBrowser/#/R-BTA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Bos taurus 58307 R-BTA-70800 https://reactome.org/PathwayBrowser/#/R-BTA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Bos taurus 58307 R-BTA-70859 https://reactome.org/PathwayBrowser/#/R-BTA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Bos taurus 58307 R-BTA-71046 https://reactome.org/PathwayBrowser/#/R-BTA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Bos taurus 58307 R-BTA-77263 https://reactome.org/PathwayBrowser/#/R-BTA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Bos taurus 58307 R-BTA-77274 https://reactome.org/PathwayBrowser/#/R-BTA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Bos taurus 58307 R-BTA-77299 https://reactome.org/PathwayBrowser/#/R-BTA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Bos taurus 58307 R-BTA-77319 https://reactome.org/PathwayBrowser/#/R-BTA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Bos taurus 58307 R-BTA-77327 https://reactome.org/PathwayBrowser/#/R-BTA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Bos taurus 58307 R-BTA-77338 https://reactome.org/PathwayBrowser/#/R-BTA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Bos taurus 58307 R-BTA-77345 https://reactome.org/PathwayBrowser/#/R-BTA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Bos taurus 58307 R-BTA-880007 https://reactome.org/PathwayBrowser/#/R-BTA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Bos taurus 58307 R-BTA-880050 https://reactome.org/PathwayBrowser/#/R-BTA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Bos taurus 58307 R-BTA-8955817 https://reactome.org/PathwayBrowser/#/R-BTA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Bos taurus 58307 R-CEL-109341 https://reactome.org/PathwayBrowser/#/R-CEL-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Caenorhabditis elegans 58307 R-CEL-169260 https://reactome.org/PathwayBrowser/#/R-CEL-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Caenorhabditis elegans 58307 R-CEL-169270 https://reactome.org/PathwayBrowser/#/R-CEL-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Caenorhabditis elegans 58307 R-CEL-188467 https://reactome.org/PathwayBrowser/#/R-CEL-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Caenorhabditis elegans 58307 R-CEL-2395512 https://reactome.org/PathwayBrowser/#/R-CEL-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Caenorhabditis elegans 58307 R-CEL-2395517 https://reactome.org/PathwayBrowser/#/R-CEL-2395517 NADPH transfers electrons to FDXR IEA Caenorhabditis elegans 58307 R-CEL-3159253 https://reactome.org/PathwayBrowser/#/R-CEL-3159253 MMAB adenosylates cob(I)alamin IEA Caenorhabditis elegans 58307 R-CEL-5695980 https://reactome.org/PathwayBrowser/#/R-CEL-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Caenorhabditis elegans 58307 R-CEL-70670 https://reactome.org/PathwayBrowser/#/R-CEL-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Caenorhabditis elegans 58307 R-CEL-70745 https://reactome.org/PathwayBrowser/#/R-CEL-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Caenorhabditis elegans 58307 R-CEL-70800 https://reactome.org/PathwayBrowser/#/R-CEL-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Caenorhabditis elegans 58307 R-CEL-70859 https://reactome.org/PathwayBrowser/#/R-CEL-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Caenorhabditis elegans 58307 R-CEL-71046 https://reactome.org/PathwayBrowser/#/R-CEL-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Caenorhabditis elegans 58307 R-CEL-77299 https://reactome.org/PathwayBrowser/#/R-CEL-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 58307 R-CEL-77338 https://reactome.org/PathwayBrowser/#/R-CEL-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 58307 R-CEL-77345 https://reactome.org/PathwayBrowser/#/R-CEL-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 58307 R-CEL-880007 https://reactome.org/PathwayBrowser/#/R-CEL-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Caenorhabditis elegans 58307 R-CEL-880050 https://reactome.org/PathwayBrowser/#/R-CEL-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Caenorhabditis elegans 58307 R-CEL-8955817 https://reactome.org/PathwayBrowser/#/R-CEL-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Caenorhabditis elegans 58307 R-CFA-109341 https://reactome.org/PathwayBrowser/#/R-CFA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Canis familiaris 58307 R-CFA-169260 https://reactome.org/PathwayBrowser/#/R-CFA-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Canis familiaris 58307 R-CFA-169270 https://reactome.org/PathwayBrowser/#/R-CFA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Canis familiaris 58307 R-CFA-188467 https://reactome.org/PathwayBrowser/#/R-CFA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Canis familiaris 58307 R-CFA-2395512 https://reactome.org/PathwayBrowser/#/R-CFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Canis familiaris 58307 R-CFA-2395517 https://reactome.org/PathwayBrowser/#/R-CFA-2395517 NADPH transfers electrons to FDXR IEA Canis familiaris 58307 R-CFA-3159253 https://reactome.org/PathwayBrowser/#/R-CFA-3159253 MMAB adenosylates cob(I)alamin IEA Canis familiaris 58307 R-CFA-5695989 https://reactome.org/PathwayBrowser/#/R-CFA-5695989 ACAD11 dehydrogenates BH-CoA IEA Canis familiaris 58307 R-CFA-70670 https://reactome.org/PathwayBrowser/#/R-CFA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Canis familiaris 58307 R-CFA-70745 https://reactome.org/PathwayBrowser/#/R-CFA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Canis familiaris 58307 R-CFA-70800 https://reactome.org/PathwayBrowser/#/R-CFA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Canis familiaris 58307 R-CFA-70859 https://reactome.org/PathwayBrowser/#/R-CFA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Canis familiaris 58307 R-CFA-71046 https://reactome.org/PathwayBrowser/#/R-CFA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Canis familiaris 58307 R-CFA-77263 https://reactome.org/PathwayBrowser/#/R-CFA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Canis familiaris 58307 R-CFA-77274 https://reactome.org/PathwayBrowser/#/R-CFA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Canis familiaris 58307 R-CFA-77299 https://reactome.org/PathwayBrowser/#/R-CFA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Canis familiaris 58307 R-CFA-77319 https://reactome.org/PathwayBrowser/#/R-CFA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Canis familiaris 58307 R-CFA-77327 https://reactome.org/PathwayBrowser/#/R-CFA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Canis familiaris 58307 R-CFA-77338 https://reactome.org/PathwayBrowser/#/R-CFA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Canis familiaris 58307 R-CFA-77345 https://reactome.org/PathwayBrowser/#/R-CFA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Canis familiaris 58307 R-CFA-880007 https://reactome.org/PathwayBrowser/#/R-CFA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Canis familiaris 58307 R-CFA-880050 https://reactome.org/PathwayBrowser/#/R-CFA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Canis familiaris 58307 R-CFA-8955817 https://reactome.org/PathwayBrowser/#/R-CFA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Canis familiaris 58307 R-DDI-169260 https://reactome.org/PathwayBrowser/#/R-DDI-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Dictyostelium discoideum 58307 R-DDI-169270 https://reactome.org/PathwayBrowser/#/R-DDI-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Dictyostelium discoideum 58307 R-DDI-188467 https://reactome.org/PathwayBrowser/#/R-DDI-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Dictyostelium discoideum 58307 R-DDI-2395512 https://reactome.org/PathwayBrowser/#/R-DDI-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Dictyostelium discoideum 58307 R-DDI-2395517 https://reactome.org/PathwayBrowser/#/R-DDI-2395517 NADPH transfers electrons to FDXR IEA Dictyostelium discoideum 58307 R-DDI-3159253 https://reactome.org/PathwayBrowser/#/R-DDI-3159253 MMAB adenosylates cob(I)alamin IEA Dictyostelium discoideum 58307 R-DDI-70670 https://reactome.org/PathwayBrowser/#/R-DDI-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Dictyostelium discoideum 58307 R-DDI-70745 https://reactome.org/PathwayBrowser/#/R-DDI-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Dictyostelium discoideum 58307 R-DDI-70800 https://reactome.org/PathwayBrowser/#/R-DDI-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Dictyostelium discoideum 58307 R-DDI-70859 https://reactome.org/PathwayBrowser/#/R-DDI-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Dictyostelium discoideum 58307 R-DDI-71046 https://reactome.org/PathwayBrowser/#/R-DDI-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Dictyostelium discoideum 58307 R-DDI-880007 https://reactome.org/PathwayBrowser/#/R-DDI-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Dictyostelium discoideum 58307 R-DDI-880050 https://reactome.org/PathwayBrowser/#/R-DDI-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Dictyostelium discoideum 58307 R-DDI-8955817 https://reactome.org/PathwayBrowser/#/R-DDI-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Dictyostelium discoideum 58307 R-DME-109341 https://reactome.org/PathwayBrowser/#/R-DME-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Drosophila melanogaster 58307 R-DME-169260 https://reactome.org/PathwayBrowser/#/R-DME-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Drosophila melanogaster 58307 R-DME-169270 https://reactome.org/PathwayBrowser/#/R-DME-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Drosophila melanogaster 58307 R-DME-188467 https://reactome.org/PathwayBrowser/#/R-DME-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Drosophila melanogaster 58307 R-DME-2395512 https://reactome.org/PathwayBrowser/#/R-DME-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Drosophila melanogaster 58307 R-DME-2395517 https://reactome.org/PathwayBrowser/#/R-DME-2395517 NADPH transfers electrons to FDXR IEA Drosophila melanogaster 58307 R-DME-70670 https://reactome.org/PathwayBrowser/#/R-DME-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Drosophila melanogaster 58307 R-DME-70745 https://reactome.org/PathwayBrowser/#/R-DME-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Drosophila melanogaster 58307 R-DME-70800 https://reactome.org/PathwayBrowser/#/R-DME-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Drosophila melanogaster 58307 R-DME-71046 https://reactome.org/PathwayBrowser/#/R-DME-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Drosophila melanogaster 58307 R-DME-77299 https://reactome.org/PathwayBrowser/#/R-DME-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 58307 R-DME-77319 https://reactome.org/PathwayBrowser/#/R-DME-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Drosophila melanogaster 58307 R-DME-77327 https://reactome.org/PathwayBrowser/#/R-DME-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 58307 R-DME-77338 https://reactome.org/PathwayBrowser/#/R-DME-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 58307 R-DME-77345 https://reactome.org/PathwayBrowser/#/R-DME-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 58307 R-DME-880007 https://reactome.org/PathwayBrowser/#/R-DME-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Drosophila melanogaster 58307 R-DME-880050 https://reactome.org/PathwayBrowser/#/R-DME-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Drosophila melanogaster 58307 R-DME-8955817 https://reactome.org/PathwayBrowser/#/R-DME-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Drosophila melanogaster 58307 R-DRE-169260 https://reactome.org/PathwayBrowser/#/R-DRE-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Danio rerio 58307 R-DRE-169270 https://reactome.org/PathwayBrowser/#/R-DRE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Danio rerio 58307 R-DRE-2395512 https://reactome.org/PathwayBrowser/#/R-DRE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Danio rerio 58307 R-DRE-2395517 https://reactome.org/PathwayBrowser/#/R-DRE-2395517 NADPH transfers electrons to FDXR IEA Danio rerio 58307 R-DRE-5695989 https://reactome.org/PathwayBrowser/#/R-DRE-5695989 ACAD11 dehydrogenates BH-CoA IEA Danio rerio 58307 R-DRE-70745 https://reactome.org/PathwayBrowser/#/R-DRE-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Danio rerio 58307 R-DRE-70859 https://reactome.org/PathwayBrowser/#/R-DRE-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Danio rerio 58307 R-DRE-71046 https://reactome.org/PathwayBrowser/#/R-DRE-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Danio rerio 58307 R-DRE-77263 https://reactome.org/PathwayBrowser/#/R-DRE-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Danio rerio 58307 R-DRE-77274 https://reactome.org/PathwayBrowser/#/R-DRE-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Danio rerio 58307 R-DRE-77299 https://reactome.org/PathwayBrowser/#/R-DRE-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Danio rerio 58307 R-DRE-77319 https://reactome.org/PathwayBrowser/#/R-DRE-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Danio rerio 58307 R-DRE-77327 https://reactome.org/PathwayBrowser/#/R-DRE-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Danio rerio 58307 R-DRE-880007 https://reactome.org/PathwayBrowser/#/R-DRE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Danio rerio 58307 R-GGA-109341 https://reactome.org/PathwayBrowser/#/R-GGA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Gallus gallus 58307 R-GGA-188467 https://reactome.org/PathwayBrowser/#/R-GGA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Gallus gallus 58307 R-GGA-2395512 https://reactome.org/PathwayBrowser/#/R-GGA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Gallus gallus 58307 R-GGA-2395517 https://reactome.org/PathwayBrowser/#/R-GGA-2395517 NADPH transfers electrons to FDXR IEA Gallus gallus 58307 R-GGA-3159253 https://reactome.org/PathwayBrowser/#/R-GGA-3159253 MMAB adenosylates cob(I)alamin IEA Gallus gallus 58307 R-GGA-373129 https://reactome.org/PathwayBrowser/#/R-GGA-373129 fumarate + FADH2 <=> succinate + FAD IEA Gallus gallus 58307 R-GGA-373147 https://reactome.org/PathwayBrowser/#/R-GGA-373147 succinate + FAD <=> fumarate + FADH2 IEA Gallus gallus 58307 R-GGA-5695989 https://reactome.org/PathwayBrowser/#/R-GGA-5695989 ACAD11 dehydrogenates BH-CoA IEA Gallus gallus 58307 R-GGA-70670 https://reactome.org/PathwayBrowser/#/R-GGA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Gallus gallus 58307 R-GGA-70745 https://reactome.org/PathwayBrowser/#/R-GGA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Gallus gallus 58307 R-GGA-70800 https://reactome.org/PathwayBrowser/#/R-GGA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Gallus gallus 58307 R-GGA-70859 https://reactome.org/PathwayBrowser/#/R-GGA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Gallus gallus 58307 R-GGA-71046 https://reactome.org/PathwayBrowser/#/R-GGA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Gallus gallus 58307 R-GGA-77263 https://reactome.org/PathwayBrowser/#/R-GGA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Gallus gallus 58307 R-GGA-77274 https://reactome.org/PathwayBrowser/#/R-GGA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Gallus gallus 58307 R-GGA-77319 https://reactome.org/PathwayBrowser/#/R-GGA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Gallus gallus 58307 R-GGA-77327 https://reactome.org/PathwayBrowser/#/R-GGA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Gallus gallus 58307 R-GGA-77338 https://reactome.org/PathwayBrowser/#/R-GGA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Gallus gallus 58307 R-GGA-77345 https://reactome.org/PathwayBrowser/#/R-GGA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Gallus gallus 58307 R-GGA-880007 https://reactome.org/PathwayBrowser/#/R-GGA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus 58307 R-GGA-880050 https://reactome.org/PathwayBrowser/#/R-GGA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus 58307 R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 58307 R-HSA-109341 https://reactome.org/PathwayBrowser/#/R-HSA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA TAS Homo sapiens 58307 R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 58307 R-HSA-169260 https://reactome.org/PathwayBrowser/#/R-HSA-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF TAS Homo sapiens 58307 R-HSA-169270 https://reactome.org/PathwayBrowser/#/R-HSA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 TAS Homo sapiens 58307 R-HSA-188467 https://reactome.org/PathwayBrowser/#/R-HSA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) TAS Homo sapiens 58307 R-HSA-2395512 https://reactome.org/PathwayBrowser/#/R-HSA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) TAS Homo sapiens 58307 R-HSA-2395517 https://reactome.org/PathwayBrowser/#/R-HSA-2395517 NADPH transfers electrons to FDXR TAS Homo sapiens 58307 R-HSA-3159253 https://reactome.org/PathwayBrowser/#/R-HSA-3159253 MMAB adenosylates cob(I)alamin TAS Homo sapiens 58307 R-HSA-5695980 https://reactome.org/PathwayBrowser/#/R-HSA-5695980 ACAD10 dehydrogenates S-2MPDA-CoA TAS Homo sapiens 58307 R-HSA-5695989 https://reactome.org/PathwayBrowser/#/R-HSA-5695989 ACAD11 dehydrogenates BH-CoA TAS Homo sapiens 58307 R-HSA-70670 https://reactome.org/PathwayBrowser/#/R-HSA-70670 PRODH oxidises L-Pro to 1PYR-5COOH TAS Homo sapiens 58307 R-HSA-70745 https://reactome.org/PathwayBrowser/#/R-HSA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 TAS Homo sapiens 58307 R-HSA-70800 https://reactome.org/PathwayBrowser/#/R-HSA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 TAS Homo sapiens 58307 R-HSA-70859 https://reactome.org/PathwayBrowser/#/R-HSA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 TAS Homo sapiens 58307 R-HSA-71046 https://reactome.org/PathwayBrowser/#/R-HSA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 TAS Homo sapiens 58307 R-HSA-77263 https://reactome.org/PathwayBrowser/#/R-HSA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 TAS Homo sapiens 58307 R-HSA-77274 https://reactome.org/PathwayBrowser/#/R-HSA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 TAS Homo sapiens 58307 R-HSA-77299 https://reactome.org/PathwayBrowser/#/R-HSA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 TAS Homo sapiens 58307 R-HSA-77319 https://reactome.org/PathwayBrowser/#/R-HSA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 TAS Homo sapiens 58307 R-HSA-77327 https://reactome.org/PathwayBrowser/#/R-HSA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 TAS Homo sapiens 58307 R-HSA-77338 https://reactome.org/PathwayBrowser/#/R-HSA-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 TAS Homo sapiens 58307 R-HSA-77345 https://reactome.org/PathwayBrowser/#/R-HSA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 TAS Homo sapiens 58307 R-HSA-880007 https://reactome.org/PathwayBrowser/#/R-HSA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 TAS Homo sapiens 58307 R-HSA-880050 https://reactome.org/PathwayBrowser/#/R-HSA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 TAS Homo sapiens 58307 R-HSA-8955817 https://reactome.org/PathwayBrowser/#/R-HSA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH TAS Homo sapiens 58307 R-MMU-109341 https://reactome.org/PathwayBrowser/#/R-MMU-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Mus musculus 58307 R-MMU-169260 https://reactome.org/PathwayBrowser/#/R-MMU-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Mus musculus 58307 R-MMU-169270 https://reactome.org/PathwayBrowser/#/R-MMU-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Mus musculus 58307 R-MMU-188467 https://reactome.org/PathwayBrowser/#/R-MMU-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Mus musculus 58307 R-MMU-2395512 https://reactome.org/PathwayBrowser/#/R-MMU-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Mus musculus 58307 R-MMU-2395517 https://reactome.org/PathwayBrowser/#/R-MMU-2395517 NADPH transfers electrons to FDXR IEA Mus musculus 58307 R-MMU-3159253 https://reactome.org/PathwayBrowser/#/R-MMU-3159253 MMAB adenosylates cob(I)alamin IEA Mus musculus 58307 R-MMU-5695980 https://reactome.org/PathwayBrowser/#/R-MMU-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Mus musculus 58307 R-MMU-5695989 https://reactome.org/PathwayBrowser/#/R-MMU-5695989 ACAD11 dehydrogenates BH-CoA IEA Mus musculus 58307 R-MMU-70670 https://reactome.org/PathwayBrowser/#/R-MMU-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Mus musculus 58307 R-MMU-70745 https://reactome.org/PathwayBrowser/#/R-MMU-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Mus musculus 58307 R-MMU-70800 https://reactome.org/PathwayBrowser/#/R-MMU-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Mus musculus 58307 R-MMU-70859 https://reactome.org/PathwayBrowser/#/R-MMU-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Mus musculus 58307 R-MMU-71046 https://reactome.org/PathwayBrowser/#/R-MMU-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Mus musculus 58307 R-MMU-77263 https://reactome.org/PathwayBrowser/#/R-MMU-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Mus musculus 58307 R-MMU-77274 https://reactome.org/PathwayBrowser/#/R-MMU-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Mus musculus 58307 R-MMU-77299 https://reactome.org/PathwayBrowser/#/R-MMU-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Mus musculus 58307 R-MMU-77319 https://reactome.org/PathwayBrowser/#/R-MMU-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Mus musculus 58307 R-MMU-77327 https://reactome.org/PathwayBrowser/#/R-MMU-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Mus musculus 58307 R-MMU-77338 https://reactome.org/PathwayBrowser/#/R-MMU-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Mus musculus 58307 R-MMU-77345 https://reactome.org/PathwayBrowser/#/R-MMU-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Mus musculus 58307 R-MMU-880007 https://reactome.org/PathwayBrowser/#/R-MMU-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Mus musculus 58307 R-MMU-880050 https://reactome.org/PathwayBrowser/#/R-MMU-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Mus musculus 58307 R-MMU-8955817 https://reactome.org/PathwayBrowser/#/R-MMU-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Mus musculus 58307 R-PFA-188467 https://reactome.org/PathwayBrowser/#/R-PFA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Plasmodium falciparum 58307 R-PFA-2395512 https://reactome.org/PathwayBrowser/#/R-PFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Plasmodium falciparum 58307 R-PFA-2395517 https://reactome.org/PathwayBrowser/#/R-PFA-2395517 NADPH transfers electrons to FDXR IEA Plasmodium falciparum 58307 R-RNO-109341 https://reactome.org/PathwayBrowser/#/R-RNO-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Rattus norvegicus 58307 R-RNO-169260 https://reactome.org/PathwayBrowser/#/R-RNO-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Rattus norvegicus 58307 R-RNO-169270 https://reactome.org/PathwayBrowser/#/R-RNO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Rattus norvegicus 58307 R-RNO-188467 https://reactome.org/PathwayBrowser/#/R-RNO-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Rattus norvegicus 58307 R-RNO-2395512 https://reactome.org/PathwayBrowser/#/R-RNO-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Rattus norvegicus 58307 R-RNO-2395517 https://reactome.org/PathwayBrowser/#/R-RNO-2395517 NADPH transfers electrons to FDXR IEA Rattus norvegicus 58307 R-RNO-3159253 https://reactome.org/PathwayBrowser/#/R-RNO-3159253 MMAB adenosylates cob(I)alamin IEA Rattus norvegicus 58307 R-RNO-5695989 https://reactome.org/PathwayBrowser/#/R-RNO-5695989 ACAD11 dehydrogenates BH-CoA IEA Rattus norvegicus 58307 R-RNO-70670 https://reactome.org/PathwayBrowser/#/R-RNO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Rattus norvegicus 58307 R-RNO-70745 https://reactome.org/PathwayBrowser/#/R-RNO-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Rattus norvegicus 58307 R-RNO-70800 https://reactome.org/PathwayBrowser/#/R-RNO-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Rattus norvegicus 58307 R-RNO-70859 https://reactome.org/PathwayBrowser/#/R-RNO-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Rattus norvegicus 58307 R-RNO-71046 https://reactome.org/PathwayBrowser/#/R-RNO-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Rattus norvegicus 58307 R-RNO-77263 https://reactome.org/PathwayBrowser/#/R-RNO-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Rattus norvegicus 58307 R-RNO-77274 https://reactome.org/PathwayBrowser/#/R-RNO-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 58307 R-RNO-77299 https://reactome.org/PathwayBrowser/#/R-RNO-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 58307 R-RNO-77319 https://reactome.org/PathwayBrowser/#/R-RNO-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Rattus norvegicus 58307 R-RNO-77327 https://reactome.org/PathwayBrowser/#/R-RNO-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 58307 R-RNO-77338 https://reactome.org/PathwayBrowser/#/R-RNO-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 58307 R-RNO-77345 https://reactome.org/PathwayBrowser/#/R-RNO-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 58307 R-RNO-880007 https://reactome.org/PathwayBrowser/#/R-RNO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Rattus norvegicus 58307 R-RNO-880050 https://reactome.org/PathwayBrowser/#/R-RNO-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Rattus norvegicus 58307 R-RNO-8955817 https://reactome.org/PathwayBrowser/#/R-RNO-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Rattus norvegicus 58307 R-SCE-169260 https://reactome.org/PathwayBrowser/#/R-SCE-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Saccharomyces cerevisiae 58307 R-SCE-169270 https://reactome.org/PathwayBrowser/#/R-SCE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Saccharomyces cerevisiae 58307 R-SCE-188467 https://reactome.org/PathwayBrowser/#/R-SCE-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Saccharomyces cerevisiae 58307 R-SCE-2395512 https://reactome.org/PathwayBrowser/#/R-SCE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Saccharomyces cerevisiae 58307 R-SCE-2395517 https://reactome.org/PathwayBrowser/#/R-SCE-2395517 NADPH transfers electrons to FDXR IEA Saccharomyces cerevisiae 58307 R-SCE-70670 https://reactome.org/PathwayBrowser/#/R-SCE-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Saccharomyces cerevisiae 58307 R-SCE-880007 https://reactome.org/PathwayBrowser/#/R-SCE-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Saccharomyces cerevisiae 58307 R-SCE-8955817 https://reactome.org/PathwayBrowser/#/R-SCE-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Saccharomyces cerevisiae 58307 R-SPO-169260 https://reactome.org/PathwayBrowser/#/R-SPO-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Schizosaccharomyces pombe 58307 R-SPO-169270 https://reactome.org/PathwayBrowser/#/R-SPO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Schizosaccharomyces pombe 58307 R-SPO-188467 https://reactome.org/PathwayBrowser/#/R-SPO-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Schizosaccharomyces pombe 58307 R-SPO-2395517 https://reactome.org/PathwayBrowser/#/R-SPO-2395517 NADPH transfers electrons to FDXR IEA Schizosaccharomyces pombe 58307 R-SPO-70670 https://reactome.org/PathwayBrowser/#/R-SPO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Schizosaccharomyces pombe 58307 R-SPO-880007 https://reactome.org/PathwayBrowser/#/R-SPO-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Schizosaccharomyces pombe 58307 R-SPO-8955817 https://reactome.org/PathwayBrowser/#/R-SPO-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Schizosaccharomyces pombe 58307 R-SSC-109341 https://reactome.org/PathwayBrowser/#/R-SSC-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA IEA Sus scrofa 58307 R-SSC-169260 https://reactome.org/PathwayBrowser/#/R-SSC-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Sus scrofa 58307 R-SSC-169270 https://reactome.org/PathwayBrowser/#/R-SSC-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Sus scrofa 58307 R-SSC-188467 https://reactome.org/PathwayBrowser/#/R-SSC-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Sus scrofa 58307 R-SSC-2395512 https://reactome.org/PathwayBrowser/#/R-SSC-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Sus scrofa 58307 R-SSC-2395517 https://reactome.org/PathwayBrowser/#/R-SSC-2395517 NADPH transfers electrons to FDXR IEA Sus scrofa 58307 R-SSC-3159253 https://reactome.org/PathwayBrowser/#/R-SSC-3159253 MMAB adenosylates cob(I)alamin IEA Sus scrofa 58307 R-SSC-5695980 https://reactome.org/PathwayBrowser/#/R-SSC-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Sus scrofa 58307 R-SSC-5695989 https://reactome.org/PathwayBrowser/#/R-SSC-5695989 ACAD11 dehydrogenates BH-CoA IEA Sus scrofa 58307 R-SSC-70670 https://reactome.org/PathwayBrowser/#/R-SSC-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Sus scrofa 58307 R-SSC-70745 https://reactome.org/PathwayBrowser/#/R-SSC-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Sus scrofa 58307 R-SSC-70800 https://reactome.org/PathwayBrowser/#/R-SSC-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Sus scrofa 58307 R-SSC-70859 https://reactome.org/PathwayBrowser/#/R-SSC-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Sus scrofa 58307 R-SSC-71046 https://reactome.org/PathwayBrowser/#/R-SSC-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Sus scrofa 58307 R-SSC-77263 https://reactome.org/PathwayBrowser/#/R-SSC-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Sus scrofa 58307 R-SSC-77274 https://reactome.org/PathwayBrowser/#/R-SSC-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Sus scrofa 58307 R-SSC-77299 https://reactome.org/PathwayBrowser/#/R-SSC-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Sus scrofa 58307 R-SSC-77319 https://reactome.org/PathwayBrowser/#/R-SSC-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Sus scrofa 58307 R-SSC-77327 https://reactome.org/PathwayBrowser/#/R-SSC-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Sus scrofa 58307 R-SSC-77338 https://reactome.org/PathwayBrowser/#/R-SSC-77338 Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 IEA Sus scrofa 58307 R-SSC-77345 https://reactome.org/PathwayBrowser/#/R-SSC-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Sus scrofa 58307 R-SSC-880007 https://reactome.org/PathwayBrowser/#/R-SSC-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa 58307 R-SSC-880050 https://reactome.org/PathwayBrowser/#/R-SSC-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa 58307 R-SSC-8955817 https://reactome.org/PathwayBrowser/#/R-SSC-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Sus scrofa 58307 R-XTR-169260 https://reactome.org/PathwayBrowser/#/R-XTR-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Xenopus tropicalis 58307 R-XTR-169270 https://reactome.org/PathwayBrowser/#/R-XTR-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to QH2 IEA Xenopus tropicalis 58307 R-XTR-188467 https://reactome.org/PathwayBrowser/#/R-XTR-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Xenopus tropicalis 58307 R-XTR-2395512 https://reactome.org/PathwayBrowser/#/R-XTR-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Xenopus tropicalis 58307 R-XTR-2395517 https://reactome.org/PathwayBrowser/#/R-XTR-2395517 NADPH transfers electrons to FDXR IEA Xenopus tropicalis 58307 R-XTR-3159253 https://reactome.org/PathwayBrowser/#/R-XTR-3159253 MMAB adenosylates cob(I)alamin IEA Xenopus tropicalis 58307 R-XTR-5695989 https://reactome.org/PathwayBrowser/#/R-XTR-5695989 ACAD11 dehydrogenates BH-CoA IEA Xenopus tropicalis 58307 R-XTR-70670 https://reactome.org/PathwayBrowser/#/R-XTR-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Xenopus tropicalis 58307 R-XTR-70745 https://reactome.org/PathwayBrowser/#/R-XTR-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Xenopus tropicalis 58307 R-XTR-70800 https://reactome.org/PathwayBrowser/#/R-XTR-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Xenopus tropicalis 58307 R-XTR-70859 https://reactome.org/PathwayBrowser/#/R-XTR-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Xenopus tropicalis 58307 R-XTR-71046 https://reactome.org/PathwayBrowser/#/R-XTR-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Xenopus tropicalis 58307 R-XTR-77263 https://reactome.org/PathwayBrowser/#/R-XTR-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Xenopus tropicalis 58307 R-XTR-77274 https://reactome.org/PathwayBrowser/#/R-XTR-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Xenopus tropicalis 58307 R-XTR-77319 https://reactome.org/PathwayBrowser/#/R-XTR-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Xenopus tropicalis 58307 R-XTR-77327 https://reactome.org/PathwayBrowser/#/R-XTR-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Xenopus tropicalis 58307 R-XTR-880007 https://reactome.org/PathwayBrowser/#/R-XTR-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Xenopus tropicalis 58307 R-XTR-880050 https://reactome.org/PathwayBrowser/#/R-XTR-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Xenopus tropicalis 58307 R-XTR-8955817 https://reactome.org/PathwayBrowser/#/R-XTR-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Xenopus tropicalis 58310 R-HSA-177160 https://reactome.org/PathwayBrowser/#/R-HSA-177160 phenylacetyl-CoA + glutamine => phenylacetyl glutamine + Coenzyme A TAS Homo sapiens 58315 R-BTA-209815 https://reactome.org/PathwayBrowser/#/R-BTA-209815 Tyrosine is monoiodinated IEA Bos taurus 58315 R-BTA-209823 https://reactome.org/PathwayBrowser/#/R-BTA-209823 Tyrosine is hydroxylated to dopa IEA Bos taurus 58315 R-BTA-209921 https://reactome.org/PathwayBrowser/#/R-BTA-209921 Monoiodinated tyrosine can be deiodinated IEA Bos taurus 58315 R-BTA-209960 https://reactome.org/PathwayBrowser/#/R-BTA-209960 Diiodinated tyrosine can be deiodinated IEA Bos taurus 58315 R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 58315 R-BTA-352158 https://reactome.org/PathwayBrowser/#/R-BTA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Bos taurus 58315 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 58315 R-BTA-352232 https://reactome.org/PathwayBrowser/#/R-BTA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Bos taurus 58315 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 58315 R-BTA-517444 https://reactome.org/PathwayBrowser/#/R-BTA-517444 TAT aminates HPP IEA Bos taurus 58315 R-BTA-5662662 https://reactome.org/PathwayBrowser/#/R-BTA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Bos taurus 58315 R-BTA-71118 https://reactome.org/PathwayBrowser/#/R-BTA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Bos taurus 58315 R-BTA-71155 https://reactome.org/PathwayBrowser/#/R-BTA-71155 TAT deaminates tyrosine IEA Bos taurus 58315 R-BTA-8955724 https://reactome.org/PathwayBrowser/#/R-BTA-8955724 TTL ligates L-Tyr to the carboxy terminus of alpha-tubulin TAS Bos taurus 58315 R-CEL-209815 https://reactome.org/PathwayBrowser/#/R-CEL-209815 Tyrosine is monoiodinated IEA Caenorhabditis elegans 58315 R-CEL-209823 https://reactome.org/PathwayBrowser/#/R-CEL-209823 Tyrosine is hydroxylated to dopa IEA Caenorhabditis elegans 58315 R-CEL-209921 https://reactome.org/PathwayBrowser/#/R-CEL-209921 Monoiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 58315 R-CEL-209960 https://reactome.org/PathwayBrowser/#/R-CEL-209960 Diiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 58315 R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 58315 R-CEL-517444 https://reactome.org/PathwayBrowser/#/R-CEL-517444 TAT aminates HPP IEA Caenorhabditis elegans 58315 R-CEL-5662662 https://reactome.org/PathwayBrowser/#/R-CEL-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Caenorhabditis elegans 58315 R-CEL-71118 https://reactome.org/PathwayBrowser/#/R-CEL-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Caenorhabditis elegans 58315 R-CEL-71155 https://reactome.org/PathwayBrowser/#/R-CEL-71155 TAT deaminates tyrosine IEA Caenorhabditis elegans 58315 R-CFA-209815 https://reactome.org/PathwayBrowser/#/R-CFA-209815 Tyrosine is monoiodinated IEA Canis familiaris 58315 R-CFA-209823 https://reactome.org/PathwayBrowser/#/R-CFA-209823 Tyrosine is hydroxylated to dopa IEA Canis familiaris 58315 R-CFA-209921 https://reactome.org/PathwayBrowser/#/R-CFA-209921 Monoiodinated tyrosine can be deiodinated IEA Canis familiaris 58315 R-CFA-209960 https://reactome.org/PathwayBrowser/#/R-CFA-209960 Diiodinated tyrosine can be deiodinated IEA Canis familiaris 58315 R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 58315 R-CFA-352158 https://reactome.org/PathwayBrowser/#/R-CFA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Canis familiaris 58315 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 58315 R-CFA-352232 https://reactome.org/PathwayBrowser/#/R-CFA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Canis familiaris 58315 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 58315 R-CFA-517444 https://reactome.org/PathwayBrowser/#/R-CFA-517444 TAT aminates HPP IEA Canis familiaris 58315 R-CFA-5662662 https://reactome.org/PathwayBrowser/#/R-CFA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Canis familiaris 58315 R-CFA-71118 https://reactome.org/PathwayBrowser/#/R-CFA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Canis familiaris 58315 R-CFA-71155 https://reactome.org/PathwayBrowser/#/R-CFA-71155 TAT deaminates tyrosine IEA Canis familiaris 58315 R-DDI-209815 https://reactome.org/PathwayBrowser/#/R-DDI-209815 Tyrosine is monoiodinated IEA Dictyostelium discoideum 58315 R-DDI-209823 https://reactome.org/PathwayBrowser/#/R-DDI-209823 Tyrosine is hydroxylated to dopa IEA Dictyostelium discoideum 58315 R-DDI-209973 https://reactome.org/PathwayBrowser/#/R-DDI-209973 Tyrosine is diiodinated IEA Dictyostelium discoideum 58315 R-DDI-352158 https://reactome.org/PathwayBrowser/#/R-DDI-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Dictyostelium discoideum 58315 R-DDI-517444 https://reactome.org/PathwayBrowser/#/R-DDI-517444 TAT aminates HPP IEA Dictyostelium discoideum 58315 R-DDI-5662662 https://reactome.org/PathwayBrowser/#/R-DDI-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Dictyostelium discoideum 58315 R-DDI-71118 https://reactome.org/PathwayBrowser/#/R-DDI-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Dictyostelium discoideum 58315 R-DDI-71155 https://reactome.org/PathwayBrowser/#/R-DDI-71155 TAT deaminates tyrosine IEA Dictyostelium discoideum 58315 R-DME-209815 https://reactome.org/PathwayBrowser/#/R-DME-209815 Tyrosine is monoiodinated IEA Drosophila melanogaster 58315 R-DME-209823 https://reactome.org/PathwayBrowser/#/R-DME-209823 Tyrosine is hydroxylated to dopa IEA Drosophila melanogaster 58315 R-DME-209921 https://reactome.org/PathwayBrowser/#/R-DME-209921 Monoiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 58315 R-DME-209960 https://reactome.org/PathwayBrowser/#/R-DME-209960 Diiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 58315 R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 58315 R-DME-352158 https://reactome.org/PathwayBrowser/#/R-DME-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Drosophila melanogaster 58315 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 58315 R-DME-352232 https://reactome.org/PathwayBrowser/#/R-DME-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Drosophila melanogaster 58315 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 58315 R-DME-517444 https://reactome.org/PathwayBrowser/#/R-DME-517444 TAT aminates HPP IEA Drosophila melanogaster 58315 R-DME-71118 https://reactome.org/PathwayBrowser/#/R-DME-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Drosophila melanogaster 58315 R-DME-71155 https://reactome.org/PathwayBrowser/#/R-DME-71155 TAT deaminates tyrosine IEA Drosophila melanogaster 58315 R-DRE-209823 https://reactome.org/PathwayBrowser/#/R-DRE-209823 Tyrosine is hydroxylated to dopa IEA Danio rerio 58315 R-DRE-209921 https://reactome.org/PathwayBrowser/#/R-DRE-209921 Monoiodinated tyrosine can be deiodinated IEA Danio rerio 58315 R-DRE-209960 https://reactome.org/PathwayBrowser/#/R-DRE-209960 Diiodinated tyrosine can be deiodinated IEA Danio rerio 58315 R-DRE-352158 https://reactome.org/PathwayBrowser/#/R-DRE-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Danio rerio 58315 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 58315 R-DRE-517444 https://reactome.org/PathwayBrowser/#/R-DRE-517444 TAT aminates HPP IEA Danio rerio 58315 R-DRE-71118 https://reactome.org/PathwayBrowser/#/R-DRE-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Danio rerio 58315 R-DRE-71155 https://reactome.org/PathwayBrowser/#/R-DRE-71155 TAT deaminates tyrosine IEA Danio rerio 58315 R-GGA-209815 https://reactome.org/PathwayBrowser/#/R-GGA-209815 Tyrosine is monoiodinated IEA Gallus gallus 58315 R-GGA-209823 https://reactome.org/PathwayBrowser/#/R-GGA-209823 Tyrosine is hydroxylated to dopa IEA Gallus gallus 58315 R-GGA-209921 https://reactome.org/PathwayBrowser/#/R-GGA-209921 Monoiodinated tyrosine can be deiodinated IEA Gallus gallus 58315 R-GGA-209960 https://reactome.org/PathwayBrowser/#/R-GGA-209960 Diiodinated tyrosine can be deiodinated IEA Gallus gallus 58315 R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 58315 R-GGA-352158 https://reactome.org/PathwayBrowser/#/R-GGA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Gallus gallus 58315 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 58315 R-GGA-517444 https://reactome.org/PathwayBrowser/#/R-GGA-517444 TAT aminates HPP IEA Gallus gallus 58315 R-GGA-5662662 https://reactome.org/PathwayBrowser/#/R-GGA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Gallus gallus 58315 R-GGA-71118 https://reactome.org/PathwayBrowser/#/R-GGA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Gallus gallus 58315 R-GGA-71155 https://reactome.org/PathwayBrowser/#/R-GGA-71155 TAT deaminates tyrosine IEA Gallus gallus 58315 R-HSA-209815 https://reactome.org/PathwayBrowser/#/R-HSA-209815 Tyrosine is monoiodinated TAS Homo sapiens 58315 R-HSA-209823 https://reactome.org/PathwayBrowser/#/R-HSA-209823 Tyrosine is hydroxylated to dopa TAS Homo sapiens 58315 R-HSA-209921 https://reactome.org/PathwayBrowser/#/R-HSA-209921 Monoiodinated tyrosine can be deiodinated TAS Homo sapiens 58315 R-HSA-209960 https://reactome.org/PathwayBrowser/#/R-HSA-209960 Diiodinated tyrosine can be deiodinated TAS Homo sapiens 58315 R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 58315 R-HSA-352158 https://reactome.org/PathwayBrowser/#/R-HSA-352158 SLC16A10-mediated uptake of aromatic amino acids TAS Homo sapiens 58315 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 58315 R-HSA-352232 https://reactome.org/PathwayBrowser/#/R-HSA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol TAS Homo sapiens 58315 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 58315 R-HSA-379980 https://reactome.org/PathwayBrowser/#/R-HSA-379980 tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 58315 R-HSA-380170 https://reactome.org/PathwayBrowser/#/R-HSA-380170 tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate TAS Homo sapiens 58315 R-HSA-517444 https://reactome.org/PathwayBrowser/#/R-HSA-517444 TAT aminates HPP TAS Homo sapiens 58315 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 58315 R-HSA-5662662 https://reactome.org/PathwayBrowser/#/R-HSA-5662662 Tyrosinase oxidises tyrosine to dopaquinone TAS Homo sapiens 58315 R-HSA-71118 https://reactome.org/PathwayBrowser/#/R-HSA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr TAS Homo sapiens 58315 R-HSA-71155 https://reactome.org/PathwayBrowser/#/R-HSA-71155 TAT deaminates tyrosine TAS Homo sapiens 58315 R-HSA-8955706 https://reactome.org/PathwayBrowser/#/R-HSA-8955706 TTL ligates L-Tyr to the carboxy terminus of detyr-alpha tubulin:beta tubulin IEA Homo sapiens 58315 R-HSA-8955712 https://reactome.org/PathwayBrowser/#/R-HSA-8955712 SVBP:VASH1,VASH2 hydrolyzes the terminal L-Tyr residue from alphaY-beta tubulin dimer IEA Homo sapiens 58315 R-MMU-209815 https://reactome.org/PathwayBrowser/#/R-MMU-209815 Tyrosine is monoiodinated IEA Mus musculus 58315 R-MMU-209823 https://reactome.org/PathwayBrowser/#/R-MMU-209823 Tyrosine is hydroxylated to dopa IEA Mus musculus 58315 R-MMU-209921 https://reactome.org/PathwayBrowser/#/R-MMU-209921 Monoiodinated tyrosine can be deiodinated IEA Mus musculus 58315 R-MMU-209960 https://reactome.org/PathwayBrowser/#/R-MMU-209960 Diiodinated tyrosine can be deiodinated IEA Mus musculus 58315 R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 58315 R-MMU-352158 https://reactome.org/PathwayBrowser/#/R-MMU-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Mus musculus 58315 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 58315 R-MMU-352232 https://reactome.org/PathwayBrowser/#/R-MMU-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Mus musculus 58315 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 58315 R-MMU-517444 https://reactome.org/PathwayBrowser/#/R-MMU-517444 TAT aminates HPP IEA Mus musculus 58315 R-MMU-5662662 https://reactome.org/PathwayBrowser/#/R-MMU-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Mus musculus 58315 R-MMU-71118 https://reactome.org/PathwayBrowser/#/R-MMU-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Mus musculus 58315 R-MMU-71155 https://reactome.org/PathwayBrowser/#/R-MMU-71155 TAT deaminates tyrosine IEA Mus musculus 58315 R-NUL-8955728 https://reactome.org/PathwayBrowser/#/R-NUL-8955728 TTCP hydrolyzes the terminal L-Tyr residue from alpha-tubulin TAS Bos taurus 58315 R-PFA-352158 https://reactome.org/PathwayBrowser/#/R-PFA-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Plasmodium falciparum 58315 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 58315 R-RNO-209815 https://reactome.org/PathwayBrowser/#/R-RNO-209815 Tyrosine is monoiodinated IEA Rattus norvegicus 58315 R-RNO-209823 https://reactome.org/PathwayBrowser/#/R-RNO-209823 Tyrosine is hydroxylated to dopa IEA Rattus norvegicus 58315 R-RNO-209921 https://reactome.org/PathwayBrowser/#/R-RNO-209921 Monoiodinated tyrosine can be deiodinated IEA Rattus norvegicus 58315 R-RNO-209960 https://reactome.org/PathwayBrowser/#/R-RNO-209960 Diiodinated tyrosine can be deiodinated IEA Rattus norvegicus 58315 R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 58315 R-RNO-352158 https://reactome.org/PathwayBrowser/#/R-RNO-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Rattus norvegicus 58315 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 58315 R-RNO-352232 https://reactome.org/PathwayBrowser/#/R-RNO-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Rattus norvegicus 58315 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 58315 R-RNO-517444 https://reactome.org/PathwayBrowser/#/R-RNO-517444 TAT aminates HPP IEA Rattus norvegicus 58315 R-RNO-5662662 https://reactome.org/PathwayBrowser/#/R-RNO-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Rattus norvegicus 58315 R-RNO-71118 https://reactome.org/PathwayBrowser/#/R-RNO-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Rattus norvegicus 58315 R-RNO-71155 https://reactome.org/PathwayBrowser/#/R-RNO-71155 TAT deaminates tyrosine IEA Rattus norvegicus 58315 R-SCE-352158 https://reactome.org/PathwayBrowser/#/R-SCE-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Saccharomyces cerevisiae 58315 R-SSC-209815 https://reactome.org/PathwayBrowser/#/R-SSC-209815 Tyrosine is monoiodinated IEA Sus scrofa 58315 R-SSC-209823 https://reactome.org/PathwayBrowser/#/R-SSC-209823 Tyrosine is hydroxylated to dopa IEA Sus scrofa 58315 R-SSC-209921 https://reactome.org/PathwayBrowser/#/R-SSC-209921 Monoiodinated tyrosine can be deiodinated IEA Sus scrofa 58315 R-SSC-209960 https://reactome.org/PathwayBrowser/#/R-SSC-209960 Diiodinated tyrosine can be deiodinated IEA Sus scrofa 58315 R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 58315 R-SSC-352158 https://reactome.org/PathwayBrowser/#/R-SSC-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Sus scrofa 58315 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 58315 R-SSC-352232 https://reactome.org/PathwayBrowser/#/R-SSC-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Sus scrofa 58315 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 58315 R-SSC-517444 https://reactome.org/PathwayBrowser/#/R-SSC-517444 TAT aminates HPP IEA Sus scrofa 58315 R-SSC-5662662 https://reactome.org/PathwayBrowser/#/R-SSC-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Sus scrofa 58315 R-SSC-71118 https://reactome.org/PathwayBrowser/#/R-SSC-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Sus scrofa 58315 R-SSC-71155 https://reactome.org/PathwayBrowser/#/R-SSC-71155 TAT deaminates tyrosine IEA Sus scrofa 58315 R-XTR-209823 https://reactome.org/PathwayBrowser/#/R-XTR-209823 Tyrosine is hydroxylated to dopa IEA Xenopus tropicalis 58315 R-XTR-209921 https://reactome.org/PathwayBrowser/#/R-XTR-209921 Monoiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 58315 R-XTR-209960 https://reactome.org/PathwayBrowser/#/R-XTR-209960 Diiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 58315 R-XTR-352158 https://reactome.org/PathwayBrowser/#/R-XTR-352158 SLC16A10-mediated uptake of aromatic amino acids IEA Xenopus tropicalis 58315 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 58315 R-XTR-352232 https://reactome.org/PathwayBrowser/#/R-XTR-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Xenopus tropicalis 58315 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 58315 R-XTR-517444 https://reactome.org/PathwayBrowser/#/R-XTR-517444 TAT aminates HPP IEA Xenopus tropicalis 58315 R-XTR-5662662 https://reactome.org/PathwayBrowser/#/R-XTR-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Xenopus tropicalis 58315 R-XTR-71118 https://reactome.org/PathwayBrowser/#/R-XTR-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Xenopus tropicalis 58315 R-XTR-71155 https://reactome.org/PathwayBrowser/#/R-XTR-71155 TAT deaminates tyrosine IEA Xenopus tropicalis 58321 R-BTA-5696408 https://reactome.org/PathwayBrowser/#/R-BTA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Bos taurus 58321 R-BTA-70940 https://reactome.org/PathwayBrowser/#/R-BTA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Bos taurus 58321 R-BTA-70941 https://reactome.org/PathwayBrowser/#/R-BTA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Bos taurus 58321 R-CEL-5696408 https://reactome.org/PathwayBrowser/#/R-CEL-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Caenorhabditis elegans 58321 R-CEL-70940 https://reactome.org/PathwayBrowser/#/R-CEL-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Caenorhabditis elegans 58321 R-CEL-70941 https://reactome.org/PathwayBrowser/#/R-CEL-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Caenorhabditis elegans 58321 R-CFA-5696408 https://reactome.org/PathwayBrowser/#/R-CFA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Canis familiaris 58321 R-CFA-70940 https://reactome.org/PathwayBrowser/#/R-CFA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Canis familiaris 58321 R-CFA-70941 https://reactome.org/PathwayBrowser/#/R-CFA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Canis familiaris 58321 R-DDI-70940 https://reactome.org/PathwayBrowser/#/R-DDI-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Dictyostelium discoideum 58321 R-DDI-70941 https://reactome.org/PathwayBrowser/#/R-DDI-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Dictyostelium discoideum 58321 R-DME-5696408 https://reactome.org/PathwayBrowser/#/R-DME-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Drosophila melanogaster 58321 R-DME-70940 https://reactome.org/PathwayBrowser/#/R-DME-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Drosophila melanogaster 58321 R-DME-70941 https://reactome.org/PathwayBrowser/#/R-DME-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Drosophila melanogaster 58321 R-DRE-5696408 https://reactome.org/PathwayBrowser/#/R-DRE-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Danio rerio 58321 R-DRE-70940 https://reactome.org/PathwayBrowser/#/R-DRE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Danio rerio 58321 R-DRE-70941 https://reactome.org/PathwayBrowser/#/R-DRE-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Danio rerio 58321 R-GGA-5696408 https://reactome.org/PathwayBrowser/#/R-GGA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Gallus gallus 58321 R-GGA-70940 https://reactome.org/PathwayBrowser/#/R-GGA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Gallus gallus 58321 R-GGA-70941 https://reactome.org/PathwayBrowser/#/R-GGA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Gallus gallus 58321 R-HSA-5696408 https://reactome.org/PathwayBrowser/#/R-HSA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL TAS Homo sapiens 58321 R-HSA-6783883 https://reactome.org/PathwayBrowser/#/R-HSA-6783883 P6C transforms to 2AMAS TAS Homo sapiens 58321 R-HSA-70940 https://reactome.org/PathwayBrowser/#/R-HSA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ TAS Homo sapiens 58321 R-HSA-70941 https://reactome.org/PathwayBrowser/#/R-HSA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ TAS Homo sapiens 58321 R-MMU-5696408 https://reactome.org/PathwayBrowser/#/R-MMU-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Mus musculus 58321 R-MMU-70940 https://reactome.org/PathwayBrowser/#/R-MMU-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Mus musculus 58321 R-MMU-70941 https://reactome.org/PathwayBrowser/#/R-MMU-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Mus musculus 58321 R-RNO-5696408 https://reactome.org/PathwayBrowser/#/R-RNO-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Rattus norvegicus 58321 R-RNO-70940 https://reactome.org/PathwayBrowser/#/R-RNO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Rattus norvegicus 58321 R-RNO-70941 https://reactome.org/PathwayBrowser/#/R-RNO-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Rattus norvegicus 58321 R-SCE-70940 https://reactome.org/PathwayBrowser/#/R-SCE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Saccharomyces cerevisiae 58321 R-SPO-70940 https://reactome.org/PathwayBrowser/#/R-SPO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Schizosaccharomyces pombe 58321 R-SSC-5696408 https://reactome.org/PathwayBrowser/#/R-SSC-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Sus scrofa 58321 R-SSC-70940 https://reactome.org/PathwayBrowser/#/R-SSC-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Sus scrofa 58321 R-SSC-70941 https://reactome.org/PathwayBrowser/#/R-SSC-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Sus scrofa 58321 R-XTR-70940 https://reactome.org/PathwayBrowser/#/R-XTR-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Xenopus tropicalis 58321 R-XTR-70941 https://reactome.org/PathwayBrowser/#/R-XTR-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Xenopus tropicalis 58326 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 58326 R-BTA-5693373 https://reactome.org/PathwayBrowser/#/R-BTA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Bos taurus 58326 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 58326 R-CFA-5693373 https://reactome.org/PathwayBrowser/#/R-CFA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Canis familiaris 58326 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 58326 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 58326 R-DME-5693373 https://reactome.org/PathwayBrowser/#/R-DME-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Drosophila melanogaster 58326 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 58326 R-GGA-5693373 https://reactome.org/PathwayBrowser/#/R-GGA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Gallus gallus 58326 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 58326 R-HSA-5693373 https://reactome.org/PathwayBrowser/#/R-HSA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit TAS Homo sapiens 58326 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 58326 R-MMU-5693373 https://reactome.org/PathwayBrowser/#/R-MMU-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Mus musculus 58326 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 58326 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 58326 R-RNO-5693373 https://reactome.org/PathwayBrowser/#/R-RNO-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Rattus norvegicus 58326 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 58326 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 58326 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 58326 R-XTR-5693373 https://reactome.org/PathwayBrowser/#/R-XTR-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit IEA Xenopus tropicalis 58332 R-BTA-1482976 https://reactome.org/PathwayBrowser/#/R-BTA-1482976 CDP-DAG is converted to PI by CDIPT IEA Bos taurus 58332 R-BTA-1483063 https://reactome.org/PathwayBrowser/#/R-BTA-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Bos taurus 58332 R-BTA-1483121 https://reactome.org/PathwayBrowser/#/R-BTA-1483121 PA is converted to CDP-DAG by CDS1 IEA Bos taurus 58332 R-BTA-1483165 https://reactome.org/PathwayBrowser/#/R-BTA-1483165 PA is converted to CDP-DAG by CDS2 IEA Bos taurus 58332 R-CEL-1482976 https://reactome.org/PathwayBrowser/#/R-CEL-1482976 CDP-DAG is converted to PI by CDIPT IEA Caenorhabditis elegans 58332 R-CEL-1483063 https://reactome.org/PathwayBrowser/#/R-CEL-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Caenorhabditis elegans 58332 R-CEL-1483121 https://reactome.org/PathwayBrowser/#/R-CEL-1483121 PA is converted to CDP-DAG by CDS1 IEA Caenorhabditis elegans 58332 R-CEL-1483165 https://reactome.org/PathwayBrowser/#/R-CEL-1483165 PA is converted to CDP-DAG by CDS2 IEA Caenorhabditis elegans 58332 R-CFA-1482976 https://reactome.org/PathwayBrowser/#/R-CFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Canis familiaris 58332 R-CFA-1483121 https://reactome.org/PathwayBrowser/#/R-CFA-1483121 PA is converted to CDP-DAG by CDS1 IEA Canis familiaris 58332 R-CFA-1483165 https://reactome.org/PathwayBrowser/#/R-CFA-1483165 PA is converted to CDP-DAG by CDS2 IEA Canis familiaris 58332 R-DDI-1482976 https://reactome.org/PathwayBrowser/#/R-DDI-1482976 CDP-DAG is converted to PI by CDIPT IEA Dictyostelium discoideum 58332 R-DDI-1483121 https://reactome.org/PathwayBrowser/#/R-DDI-1483121 PA is converted to CDP-DAG by CDS1 IEA Dictyostelium discoideum 58332 R-DDI-1483165 https://reactome.org/PathwayBrowser/#/R-DDI-1483165 PA is converted to CDP-DAG by CDS2 IEA Dictyostelium discoideum 58332 R-DME-1482976 https://reactome.org/PathwayBrowser/#/R-DME-1482976 CDP-DAG is converted to PI by CDIPT IEA Drosophila melanogaster 58332 R-DME-1483063 https://reactome.org/PathwayBrowser/#/R-DME-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Drosophila melanogaster 58332 R-DME-1483121 https://reactome.org/PathwayBrowser/#/R-DME-1483121 PA is converted to CDP-DAG by CDS1 IEA Drosophila melanogaster 58332 R-DME-1483165 https://reactome.org/PathwayBrowser/#/R-DME-1483165 PA is converted to CDP-DAG by CDS2 IEA Drosophila melanogaster 58332 R-DRE-1482976 https://reactome.org/PathwayBrowser/#/R-DRE-1482976 CDP-DAG is converted to PI by CDIPT IEA Danio rerio 58332 R-DRE-1483063 https://reactome.org/PathwayBrowser/#/R-DRE-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Danio rerio 58332 R-DRE-1483165 https://reactome.org/PathwayBrowser/#/R-DRE-1483165 PA is converted to CDP-DAG by CDS2 IEA Danio rerio 58332 R-GGA-1483063 https://reactome.org/PathwayBrowser/#/R-GGA-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Gallus gallus 58332 R-GGA-1483121 https://reactome.org/PathwayBrowser/#/R-GGA-1483121 PA is converted to CDP-DAG by CDS1 IEA Gallus gallus 58332 R-GGA-1483165 https://reactome.org/PathwayBrowser/#/R-GGA-1483165 PA is converted to CDP-DAG by CDS2 IEA Gallus gallus 58332 R-HSA-1482939 https://reactome.org/PathwayBrowser/#/R-HSA-1482939 CDP-DAG is converted to PGP by PGS1 IEA Homo sapiens 58332 R-HSA-1482976 https://reactome.org/PathwayBrowser/#/R-HSA-1482976 CDP-DAG is converted to PI by CDIPT TAS Homo sapiens 58332 R-HSA-1483063 https://reactome.org/PathwayBrowser/#/R-HSA-1483063 PG and CDP-DAG are converted to CL by CRLS1 TAS Homo sapiens 58332 R-HSA-1483121 https://reactome.org/PathwayBrowser/#/R-HSA-1483121 PA is converted to CDP-DAG by CDS1 TAS Homo sapiens 58332 R-HSA-1483165 https://reactome.org/PathwayBrowser/#/R-HSA-1483165 PA is converted to CDP-DAG by CDS2 TAS Homo sapiens 58332 R-MMU-1482976 https://reactome.org/PathwayBrowser/#/R-MMU-1482976 CDP-DAG is converted to PI by CDIPT IEA Mus musculus 58332 R-MMU-1483063 https://reactome.org/PathwayBrowser/#/R-MMU-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Mus musculus 58332 R-MMU-1483121 https://reactome.org/PathwayBrowser/#/R-MMU-1483121 PA is converted to CDP-DAG by CDS1 IEA Mus musculus 58332 R-MMU-1483165 https://reactome.org/PathwayBrowser/#/R-MMU-1483165 PA is converted to CDP-DAG by CDS2 IEA Mus musculus 58332 R-PFA-1482976 https://reactome.org/PathwayBrowser/#/R-PFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Plasmodium falciparum 58332 R-PFA-1483121 https://reactome.org/PathwayBrowser/#/R-PFA-1483121 PA is converted to CDP-DAG by CDS1 IEA Plasmodium falciparum 58332 R-PFA-1483165 https://reactome.org/PathwayBrowser/#/R-PFA-1483165 PA is converted to CDP-DAG by CDS2 IEA Plasmodium falciparum 58332 R-RNO-1482976 https://reactome.org/PathwayBrowser/#/R-RNO-1482976 CDP-DAG is converted to PI by CDIPT IEA Rattus norvegicus 58332 R-RNO-1482978 https://reactome.org/PathwayBrowser/#/R-RNO-1482978 CDP-DAG is converted to PGP by Pgs1 TAS Rattus norvegicus 58332 R-RNO-1483063 https://reactome.org/PathwayBrowser/#/R-RNO-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Rattus norvegicus 58332 R-RNO-1483121 https://reactome.org/PathwayBrowser/#/R-RNO-1483121 PA is converted to CDP-DAG by CDS1 IEA Rattus norvegicus 58332 R-RNO-1483165 https://reactome.org/PathwayBrowser/#/R-RNO-1483165 PA is converted to CDP-DAG by CDS2 IEA Rattus norvegicus 58332 R-SCE-1482976 https://reactome.org/PathwayBrowser/#/R-SCE-1482976 CDP-DAG is converted to PI by CDIPT IEA Saccharomyces cerevisiae 58332 R-SCE-1483063 https://reactome.org/PathwayBrowser/#/R-SCE-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Saccharomyces cerevisiae 58332 R-SCE-1483121 https://reactome.org/PathwayBrowser/#/R-SCE-1483121 PA is converted to CDP-DAG by CDS1 IEA Saccharomyces cerevisiae 58332 R-SCE-1483165 https://reactome.org/PathwayBrowser/#/R-SCE-1483165 PA is converted to CDP-DAG by CDS2 IEA Saccharomyces cerevisiae 58332 R-SPO-1482976 https://reactome.org/PathwayBrowser/#/R-SPO-1482976 CDP-DAG is converted to PI by CDIPT IEA Schizosaccharomyces pombe 58332 R-SPO-1483063 https://reactome.org/PathwayBrowser/#/R-SPO-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Schizosaccharomyces pombe 58332 R-SPO-1483121 https://reactome.org/PathwayBrowser/#/R-SPO-1483121 PA is converted to CDP-DAG by CDS1 IEA Schizosaccharomyces pombe 58332 R-SPO-1483165 https://reactome.org/PathwayBrowser/#/R-SPO-1483165 PA is converted to CDP-DAG by CDS2 IEA Schizosaccharomyces pombe 58332 R-SSC-1482976 https://reactome.org/PathwayBrowser/#/R-SSC-1482976 CDP-DAG is converted to PI by CDIPT IEA Sus scrofa 58332 R-SSC-1483063 https://reactome.org/PathwayBrowser/#/R-SSC-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Sus scrofa 58332 R-SSC-1483121 https://reactome.org/PathwayBrowser/#/R-SSC-1483121 PA is converted to CDP-DAG by CDS1 IEA Sus scrofa 58332 R-SSC-1483165 https://reactome.org/PathwayBrowser/#/R-SSC-1483165 PA is converted to CDP-DAG by CDS2 IEA Sus scrofa 58332 R-XTR-1482976 https://reactome.org/PathwayBrowser/#/R-XTR-1482976 CDP-DAG is converted to PI by CDIPT IEA Xenopus tropicalis 58332 R-XTR-1483121 https://reactome.org/PathwayBrowser/#/R-XTR-1483121 PA is converted to CDP-DAG by CDS1 IEA Xenopus tropicalis 58332 R-XTR-1483165 https://reactome.org/PathwayBrowser/#/R-XTR-1483165 PA is converted to CDP-DAG by CDS2 IEA Xenopus tropicalis 58339 R-BTA-158468 https://reactome.org/PathwayBrowser/#/R-BTA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Bos taurus 58339 R-BTA-158849 https://reactome.org/PathwayBrowser/#/R-BTA-158849 Phenol can form a sulfate conjugate IEA Bos taurus 58339 R-BTA-158860 https://reactome.org/PathwayBrowser/#/R-BTA-158860 SULT1A1 dimer sulfonates NHABP IEA Bos taurus 58339 R-BTA-159358 https://reactome.org/PathwayBrowser/#/R-BTA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Bos taurus 58339 R-BTA-174389 https://reactome.org/PathwayBrowser/#/R-BTA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Bos taurus 58339 R-BTA-176474 https://reactome.org/PathwayBrowser/#/R-BTA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Bos taurus 58339 R-BTA-176494 https://reactome.org/PathwayBrowser/#/R-BTA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Bos taurus 58339 R-BTA-176517 https://reactome.org/PathwayBrowser/#/R-BTA-176517 SULTs transfer (SO4)2- group to PREG IEA Bos taurus 58339 R-BTA-176521 https://reactome.org/PathwayBrowser/#/R-BTA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Bos taurus 58339 R-BTA-176585 https://reactome.org/PathwayBrowser/#/R-BTA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Bos taurus 58339 R-BTA-176588 https://reactome.org/PathwayBrowser/#/R-BTA-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Bos taurus 58339 R-BTA-176604 https://reactome.org/PathwayBrowser/#/R-BTA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Bos taurus 58339 R-BTA-176609 https://reactome.org/PathwayBrowser/#/R-BTA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Bos taurus 58339 R-BTA-176631 https://reactome.org/PathwayBrowser/#/R-BTA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Bos taurus 58339 R-BTA-176646 https://reactome.org/PathwayBrowser/#/R-BTA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Bos taurus 58339 R-BTA-176664 https://reactome.org/PathwayBrowser/#/R-BTA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Bos taurus 58339 R-BTA-176669 https://reactome.org/PathwayBrowser/#/R-BTA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Bos taurus 58339 R-BTA-1971483 https://reactome.org/PathwayBrowser/#/R-BTA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Bos taurus 58339 R-BTA-2018659 https://reactome.org/PathwayBrowser/#/R-BTA-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Bos taurus 58339 R-BTA-2018682 https://reactome.org/PathwayBrowser/#/R-BTA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Bos taurus 58339 R-BTA-2022061 https://reactome.org/PathwayBrowser/#/R-BTA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Bos taurus 58339 R-BTA-2022063 https://reactome.org/PathwayBrowser/#/R-BTA-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Bos taurus 58339 R-BTA-2022860 https://reactome.org/PathwayBrowser/#/R-BTA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Bos taurus 58339 R-BTA-2046175 https://reactome.org/PathwayBrowser/#/R-BTA-2046175 Further sulfation on galactose residues produces KSPG IEA Bos taurus 58339 R-BTA-2046222 https://reactome.org/PathwayBrowser/#/R-BTA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Bos taurus 58339 R-BTA-2076383 https://reactome.org/PathwayBrowser/#/R-BTA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Bos taurus 58339 R-BTA-2076419 https://reactome.org/PathwayBrowser/#/R-BTA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Bos taurus 58339 R-BTA-2076508 https://reactome.org/PathwayBrowser/#/R-BTA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Bos taurus 58339 R-BTA-2076611 https://reactome.org/PathwayBrowser/#/R-BTA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Bos taurus 58339 R-BTA-6786012 https://reactome.org/PathwayBrowser/#/R-BTA-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Bos taurus 58339 R-BTA-6786034 https://reactome.org/PathwayBrowser/#/R-BTA-6786034 CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin IEA Bos taurus 58339 R-BTA-6786048 https://reactome.org/PathwayBrowser/#/R-BTA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Bos taurus 58339 R-BTA-741449 https://reactome.org/PathwayBrowser/#/R-BTA-741449 SLC35B2,3 transport cytosolic PAPS to Golgi lumen IEA Bos taurus 58339 R-BTA-8954262 https://reactome.org/PathwayBrowser/#/R-BTA-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Bos taurus 58339 R-BTA-9668023 https://reactome.org/PathwayBrowser/#/R-BTA-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII IEA Bos taurus 58339 R-BTA-9753277 https://reactome.org/PathwayBrowser/#/R-BTA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Bos taurus 58339 R-BTA-9844587 https://reactome.org/PathwayBrowser/#/R-BTA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Bos taurus 58339 R-CEL-174389 https://reactome.org/PathwayBrowser/#/R-CEL-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Caenorhabditis elegans 58339 R-CEL-176474 https://reactome.org/PathwayBrowser/#/R-CEL-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Caenorhabditis elegans 58339 R-CEL-176585 https://reactome.org/PathwayBrowser/#/R-CEL-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Caenorhabditis elegans 58339 R-CEL-2022860 https://reactome.org/PathwayBrowser/#/R-CEL-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Caenorhabditis elegans 58339 R-CEL-2076383 https://reactome.org/PathwayBrowser/#/R-CEL-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Caenorhabditis elegans 58339 R-CEL-2076419 https://reactome.org/PathwayBrowser/#/R-CEL-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Caenorhabditis elegans 58339 R-CEL-2076508 https://reactome.org/PathwayBrowser/#/R-CEL-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Caenorhabditis elegans 58339 R-CEL-2076611 https://reactome.org/PathwayBrowser/#/R-CEL-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Caenorhabditis elegans 58339 R-CEL-741449 https://reactome.org/PathwayBrowser/#/R-CEL-741449 SLC35B2,3 transport cytosolic PAPS to Golgi lumen IEA Caenorhabditis elegans 58339 R-CFA-158468 https://reactome.org/PathwayBrowser/#/R-CFA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Canis familiaris 58339 R-CFA-158849 https://reactome.org/PathwayBrowser/#/R-CFA-158849 Phenol can form a sulfate conjugate IEA Canis familiaris 58339 R-CFA-158860 https://reactome.org/PathwayBrowser/#/R-CFA-158860 SULT1A1 dimer sulfonates NHABP IEA Canis familiaris 58339 R-CFA-159358 https://reactome.org/PathwayBrowser/#/R-CFA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Canis familiaris 58339 R-CFA-174389 https://reactome.org/PathwayBrowser/#/R-CFA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Canis familiaris 58339 R-CFA-176474 https://reactome.org/PathwayBrowser/#/R-CFA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Canis familiaris 58339 R-CFA-176494 https://reactome.org/PathwayBrowser/#/R-CFA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Canis familiaris 58339 R-CFA-176517 https://reactome.org/PathwayBrowser/#/R-CFA-176517 SULTs transfer (SO4)2- group to PREG IEA Canis familiaris 58339 R-CFA-176521 https://reactome.org/PathwayBrowser/#/R-CFA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Canis familiaris 58339 R-CFA-176585 https://reactome.org/PathwayBrowser/#/R-CFA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Canis familiaris 58339 R-CFA-176609 https://reactome.org/PathwayBrowser/#/R-CFA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Canis familiaris 58339 R-CFA-176631 https://reactome.org/PathwayBrowser/#/R-CFA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Canis familiaris 58339 R-CFA-176646 https://reactome.org/PathwayBrowser/#/R-CFA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Canis familiaris 58339 R-CFA-176664 https://reactome.org/PathwayBrowser/#/R-CFA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Canis familiaris 58339 R-CFA-176669 https://reactome.org/PathwayBrowser/#/R-CFA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Canis familiaris 58339 R-CFA-1971483 https://reactome.org/PathwayBrowser/#/R-CFA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Canis familiaris 58339 R-CFA-2018682 https://reactome.org/PathwayBrowser/#/R-CFA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Canis familiaris 58339 R-CFA-2022061 https://reactome.org/PathwayBrowser/#/R-CFA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Canis familiaris 58339 R-CFA-2022860 https://reactome.org/PathwayBrowser/#/R-CFA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Canis familiaris 58339 R-CFA-2046175 https://reactome.org/PathwayBrowser/#/R-CFA-2046175 Further sulfation on galactose residues produces KSPG IEA Canis familiaris 58339 R-CFA-2046222 https://reactome.org/PathwayBrowser/#/R-CFA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Canis familiaris 58339 R-CFA-2076383 https://reactome.org/PathwayBrowser/#/R-CFA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Canis familiaris 58339 R-CFA-2076419 https://reactome.org/PathwayBrowser/#/R-CFA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Canis familiaris 58339 R-CFA-2076508 https://reactome.org/PathwayBrowser/#/R-CFA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Canis familiaris 58339 R-CFA-2076611 https://reactome.org/PathwayBrowser/#/R-CFA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Canis familiaris 58339 R-CFA-6786012 https://reactome.org/PathwayBrowser/#/R-CFA-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Canis familiaris 58339 R-CFA-6786048 https://reactome.org/PathwayBrowser/#/R-CFA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Canis familiaris 58339 R-CFA-741449 https://reactome.org/PathwayBrowser/#/R-CFA-741449 SLC35B2,3 transport cytosolic PAPS to Golgi lumen IEA Canis familiaris 58339 R-CFA-8954262 https://reactome.org/PathwayBrowser/#/R-CFA-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Canis familiaris 58339 R-CFA-9753277 https://reactome.org/PathwayBrowser/#/R-CFA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Canis familiaris 58339 R-DDI-741449 https://reactome.org/PathwayBrowser/#/R-DDI-741449 SLC35B2,3 transport cytosolic PAPS to Golgi lumen IEA Dictyostelium discoideum 58339 R-DME-158468 https://reactome.org/PathwayBrowser/#/R-DME-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Drosophila melanogaster 58339 R-DME-158849 https://reactome.org/PathwayBrowser/#/R-DME-158849 Phenol can form a sulfate conjugate IEA Drosophila melanogaster 58339 R-DME-158860 https://reactome.org/PathwayBrowser/#/R-DME-158860 SULT1A1 dimer sulfonates NHABP IEA Drosophila melanogaster 58339 R-DME-159358 https://reactome.org/PathwayBrowser/#/R-DME-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Drosophila melanogaster 58339 R-DME-174389 https://reactome.org/PathwayBrowser/#/R-DME-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Drosophila melanogaster 58339 R-DME-176474 https://reactome.org/PathwayBrowser/#/R-DME-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Drosophila melanogaster 58339 R-DME-176494 https://reactome.org/PathwayBrowser/#/R-DME-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Drosophila melanogaster 58339 R-DME-176517 https://reactome.org/PathwayBrowser/#/R-DME-176517 SULTs transfer (SO4)2- group to PREG IEA Drosophila melanogaster 58339 R-DME-176521 https://reactome.org/PathwayBrowser/#/R-DME-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Drosophila melanogaster 58339 R-DME-176585 https://reactome.org/PathwayBrowser/#/R-DME-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Drosophila melanogaster 58339 R-DME-176588 https://reactome.org/PathwayBrowser/#/R-DME-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Drosophila melanogaster 58339 R-DME-176604 https://reactome.org/PathwayBrowser/#/R-DME-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Drosophila melanogaster 58339 R-DME-176609 https://reactome.org/PathwayBrowser/#/R-DME-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Drosophila melanogaster 58339 R-DME-176631 https://reactome.org/PathwayBrowser/#/R-DME-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Drosophila melanogaster 58339 R-DME-176646 https://reactome.org/PathwayBrowser/#/R-DME-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Drosophila melanogaster 58339 R-DME-176664 https://reactome.org/PathwayBrowser/#/R-DME-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Drosophila melanogaster 58339 R-DME-176669 https://reactome.org/PathwayBrowser/#/R-DME-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Drosophila melanogaster 58339 R-DME-1971483 https://reactome.org/PathwayBrowser/#/R-DME-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Drosophila melanogaster 58339 R-DME-2018682 https://reactome.org/PathwayBrowser/#/R-DME-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Drosophila melanogaster 58339 R-DME-2022061 https://reactome.org/PathwayBrowser/#/R-DME-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Drosophila melanogaster 58339 R-DME-2022860 https://reactome.org/PathwayBrowser/#/R-DME-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Drosophila melanogaster 58339 R-DME-2046175 https://reactome.org/PathwayBrowser/#/R-DME-2046175 Further sulfation on galactose residues produces KSPG IEA Drosophila melanogaster 58339 R-DME-2046222 https://reactome.org/PathwayBrowser/#/R-DME-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Drosophila melanogaster 58339 R-DME-2076383 https://reactome.org/PathwayBrowser/#/R-DME-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Drosophila melanogaster 58339 R-DME-2076419 https://reactome.org/PathwayBrowser/#/R-DME-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Drosophila melanogaster 58339 R-DME-2076508 https://reactome.org/PathwayBrowser/#/R-DME-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Drosophila melanogaster 58339 R-DME-2076611 https://reactome.org/PathwayBrowser/#/R-DME-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Drosophila melanogaster 58339 R-DME-6786012 https://reactome.org/PathwayBrowser/#/R-DME-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Drosophila melanogaster 58339 R-DME-6786048 https://reactome.org/PathwayBrowser/#/R-DME-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Drosophila melanogaster 58339 R-DME-741449 https://reactome.org/PathwayBrowser/#/R-DME-741449 SLC35B2,3 transport cytosolic PAPS to Golgi lumen IEA Drosophila melanogaster 58339 R-DME-9753277 https://reactome.org/PathwayBrowser/#/R-DME-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Drosophila melanogaster 58339 R-DRE-158468 https://reactome.org/PathwayBrowser/#/R-DRE-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Danio rerio 58339 R-DRE-158849 https://reactome.org/PathwayBrowser/#/R-DRE-158849 Phenol can form a sulfate conjugate IEA Danio rerio 58339 R-DRE-158860 https://reactome.org/PathwayBrowser/#/R-DRE-158860 SULT1A1 dimer sulfonates NHABP IEA Danio rerio 58339 R-DRE-159358 https://reactome.org/PathwayBrowser/#/R-DRE-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Danio rerio 58339 R-DRE-174389 https://reactome.org/PathwayBrowser/#/R-DRE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Danio rerio 58339 R-DRE-176474 https://reactome.org/PathwayBrowser/#/R-DRE-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Danio rerio 58339 R-DRE-176494 https://reactome.org/PathwayBrowser/#/R-DRE-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Danio rerio 58339 R-DRE-176517 https://reactome.org/PathwayBrowser/#/R-DRE-176517 SULTs transfer (SO4)2- group to PREG IEA Danio rerio 58339 R-DRE-176521 https://reactome.org/PathwayBrowser/#/R-DRE-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Danio rerio 58339 R-DRE-176585 https://reactome.org/PathwayBrowser/#/R-DRE-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Danio rerio 58339 R-DRE-176588 https://reactome.org/PathwayBrowser/#/R-DRE-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Danio rerio 58339 R-DRE-176604 https://reactome.org/PathwayBrowser/#/R-DRE-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Danio rerio 58339 R-DRE-176609 https://reactome.org/PathwayBrowser/#/R-DRE-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Danio rerio 58339 R-DRE-176631 https://reactome.org/PathwayBrowser/#/R-DRE-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Danio rerio 58339 R-DRE-176646 https://reactome.org/PathwayBrowser/#/R-DRE-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Danio rerio 58339 R-DRE-176664 https://reactome.org/PathwayBrowser/#/R-DRE-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Danio rerio 58339 R-DRE-176669 https://reactome.org/PathwayBrowser/#/R-DRE-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Danio rerio 58339 R-DRE-1971483 https://reactome.org/PathwayBrowser/#/R-DRE-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Danio rerio 58339 R-DRE-2018659 https://reactome.org/PathwayBrowser/#/R-DRE-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Danio rerio 58339 R-DRE-2018682 https://reactome.org/PathwayBrowser/#/R-DRE-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Danio rerio 58339 R-DRE-2022063 https://reactome.org/PathwayBrowser/#/R-DRE-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Danio rerio 58339 R-DRE-2022860 https://reactome.org/PathwayBrowser/#/R-DRE-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Danio rerio 58339 R-DRE-2046175 https://reactome.org/PathwayBrowser/#/R-DRE-2046175 Further sulfation on galactose residues produces KSPG IEA Danio rerio 58339 R-DRE-2076419 https://reactome.org/PathwayBrowser/#/R-DRE-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Danio rerio 58339 R-DRE-2076508 https://reactome.org/PathwayBrowser/#/R-DRE-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Danio rerio 58339 R-DRE-2076611 https://reactome.org/PathwayBrowser/#/R-DRE-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Danio rerio 58339 R-DRE-6786048 https://reactome.org/PathwayBrowser/#/R-DRE-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Danio rerio 58339 R-DRE-741449 https://reactome.org/PathwayBrowser/#/R-DRE-741449 SLC35B2,3 transport cytosolic PAPS to Golgi lumen IEA Danio rerio 58339 R-DRE-9753277 https://reactome.org/PathwayBrowser/#/R-DRE-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Danio rerio 58339 R-DRE-9844587 https://reactome.org/PathwayBrowser/#/R-DRE-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Danio rerio 58339 R-GGA-158468 https://reactome.org/PathwayBrowser/#/R-GGA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Gallus gallus 58339 R-GGA-158849 https://reactome.org/PathwayBrowser/#/R-GGA-158849 Phenol can form a sulfate conjugate IEA Gallus gallus 58339 R-GGA-158860 https://reactome.org/PathwayBrowser/#/R-GGA-158860 SULT1A1 dimer sulfonates NHABP IEA Gallus gallus 58339 R-GGA-159358 https://reactome.org/PathwayBrowser/#/R-GGA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Gallus gallus 58339 R-GGA-174389 https://reactome.org/PathwayBrowser/#/R-GGA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Gallus gallus 58339 R-GGA-176474 https://reactome.org/PathwayBrowser/#/R-GGA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Gallus gallus 58339 R-GGA-176494 https://reactome.org/PathwayBrowser/#/R-GGA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Gallus gallus 58339 R-GGA-176517 https://reactome.org/PathwayBrowser/#/R-GGA-176517 SULTs transfer (SO4)2- group to PREG IEA Gallus gallus 58339 R-GGA-176521 https://reactome.org/PathwayBrowser/#/R-GGA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Gallus gallus 58339 R-GGA-176585 https://reactome.org/PathwayBrowser/#/R-GGA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Gallus gallus 58339 R-GGA-176588 https://reactome.org/PathwayBrowser/#/R-GGA-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Gallus gallus 58339 R-GGA-176604 https://reactome.org/PathwayBrowser/#/R-GGA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Gallus gallus 58339 R-GGA-176609 https://reactome.org/PathwayBrowser/#/R-GGA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Gallus gallus 58339 R-GGA-176631 https://reactome.org/PathwayBrowser/#/R-GGA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Gallus gallus 58339 R-GGA-176646 https://reactome.org/PathwayBrowser/#/R-GGA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Gallus gallus 58339 R-GGA-176664 https://reactome.org/PathwayBrowser/#/R-GGA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Gallus gallus 58339 R-GGA-176669 https://reactome.org/PathwayBrowser/#/R-GGA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Gallus gallus 58339 R-GGA-1971483 https://reactome.org/PathwayBrowser/#/R-GGA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Gallus gallus 58339 R-GGA-2018659 https://reactome.org/PathwayBrowser/#/R-GGA-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Gallus gallus 58339 R-GGA-2018682 https://reactome.org/PathwayBrowser/#/R-GGA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Gallus gallus 58339 R-GGA-2022061 https://reactome.org/PathwayBrowser/#/R-GGA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Gallus gallus 58339 R-GGA-2022063 https://reactome.org/PathwayBrowser/#/R-GGA-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Gallus gallus 58339 R-GGA-2022860 https://reactome.org/PathwayBrowser/#/R-GGA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Gallus gallus 58339 R-GGA-2046175 https://reactome.org/PathwayBrowser/#/R-GGA-2046175 Further sulfation on galactose residues produces KSPG IEA Gallus gallus 58339 R-GGA-2046222 https://reactome.org/PathwayBrowser/#/R-GGA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Gallus gallus 58339 R-GGA-2076383 https://reactome.org/PathwayBrowser/#/R-GGA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Gallus gallus 58339 R-GGA-2076419 https://reactome.org/PathwayBrowser/#/R-GGA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Gallus gallus 58339 R-GGA-2076508 https://reactome.org/PathwayBrowser/#/R-GGA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Gallus gallus 58339 R-GGA-2076611 https://reactome.org/PathwayBrowser/#/R-GGA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Gallus gallus 58339 R-GGA-6786012 https://reactome.org/PathwayBrowser/#/R-GGA-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Gallus gallus 58339 R-GGA-6786048 https://reactome.org/PathwayBrowser/#/R-GGA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Gallus gallus 58339 R-GGA-741449 https://reactome.org/PathwayBrowser/#/R-GGA-741449 SLC35B2,3 transport cytosolic PAPS to Golgi lumen IEA Gallus gallus 58339 R-GGA-8954262 https://reactome.org/PathwayBrowser/#/R-GGA-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Gallus gallus 58339 R-GGA-9668023 https://reactome.org/PathwayBrowser/#/R-GGA-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII IEA Gallus gallus 58339 R-GGA-9753277 https://reactome.org/PathwayBrowser/#/R-GGA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Gallus gallus 58339 R-GGA-9844587 https://reactome.org/PathwayBrowser/#/R-GGA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Gallus gallus 58339 R-HSA-158468 https://reactome.org/PathwayBrowser/#/R-HSA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 TAS Homo sapiens 58339 R-HSA-158849 https://reactome.org/PathwayBrowser/#/R-HSA-158849 Phenol can form a sulfate conjugate TAS Homo sapiens 58339 R-HSA-158860 https://reactome.org/PathwayBrowser/#/R-HSA-158860 SULT1A1 dimer sulfonates NHABP TAS Homo sapiens 58339 R-HSA-159358 https://reactome.org/PathwayBrowser/#/R-HSA-159358 SULT1A3,4 dimers sulfate DA to DAOS TAS Homo sapiens 58339 R-HSA-174389 https://reactome.org/PathwayBrowser/#/R-HSA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS TAS Homo sapiens 58339 R-HSA-176474 https://reactome.org/PathwayBrowser/#/R-HSA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP TAS Homo sapiens 58339 R-HSA-176494 https://reactome.org/PathwayBrowser/#/R-HSA-176494 SULTs transfer (SO4)2- group to 27HCHOL TAS Homo sapiens 58339 R-HSA-176517 https://reactome.org/PathwayBrowser/#/R-HSA-176517 SULTs transfer (SO4)2- group to PREG TAS Homo sapiens 58339 R-HSA-176521 https://reactome.org/PathwayBrowser/#/R-HSA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP TAS Homo sapiens 58339 R-HSA-176585 https://reactome.org/PathwayBrowser/#/R-HSA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP TAS Homo sapiens 58339 R-HSA-176588 https://reactome.org/PathwayBrowser/#/R-HSA-176588 lithocholate + PAPS => lithocholate sulfate + PAP TAS Homo sapiens 58339 R-HSA-176604 https://reactome.org/PathwayBrowser/#/R-HSA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP TAS Homo sapiens 58339 R-HSA-176609 https://reactome.org/PathwayBrowser/#/R-HSA-176609 cholesterol + PAPS => cholesterol sulfate + PAP TAS Homo sapiens 58339 R-HSA-176631 https://reactome.org/PathwayBrowser/#/R-HSA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP TAS Homo sapiens 58339 R-HSA-176646 https://reactome.org/PathwayBrowser/#/R-HSA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP TAS Homo sapiens 58339 R-HSA-176664 https://reactome.org/PathwayBrowser/#/R-HSA-176664 estrone + PAPS => estrone 3-sulfate + PAP TAS Homo sapiens 58339 R-HSA-176669 https://reactome.org/PathwayBrowser/#/R-HSA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP TAS Homo sapiens 58339 R-HSA-1971483 https://reactome.org/PathwayBrowser/#/R-HSA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 TAS Homo sapiens 58339 R-HSA-2018659 https://reactome.org/PathwayBrowser/#/R-HSA-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 TAS Homo sapiens 58339 R-HSA-2018682 https://reactome.org/PathwayBrowser/#/R-HSA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains TAS Homo sapiens 58339 R-HSA-2022061 https://reactome.org/PathwayBrowser/#/R-HSA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate TAS Homo sapiens 58339 R-HSA-2022063 https://reactome.org/PathwayBrowser/#/R-HSA-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS TAS Homo sapiens 58339 R-HSA-2022860 https://reactome.org/PathwayBrowser/#/R-HSA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) TAS Homo sapiens 58339 R-HSA-2046175 https://reactome.org/PathwayBrowser/#/R-HSA-2046175 Further sulfation on galactose residues produces KSPG TAS Homo sapiens 58339 R-HSA-2046222 https://reactome.org/PathwayBrowser/#/R-HSA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG TAS Homo sapiens 58339 R-HSA-2076383 https://reactome.org/PathwayBrowser/#/R-HSA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate TAS Homo sapiens 58339 R-HSA-2076419 https://reactome.org/PathwayBrowser/#/R-HSA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin TAS Homo sapiens 58339 R-HSA-2076508 https://reactome.org/PathwayBrowser/#/R-HSA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate TAS Homo sapiens 58339 R-HSA-2076611 https://reactome.org/PathwayBrowser/#/R-HSA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate TAS Homo sapiens 58339 R-HSA-3595175 https://reactome.org/PathwayBrowser/#/R-HSA-3595175 Defective CHST3 does not transfer SO4(2-) to chondroitin TAS Homo sapiens 58339 R-HSA-3636919 https://reactome.org/PathwayBrowser/#/R-HSA-3636919 Defective CHST14 does not transfer SO4(2-) to GalNAc in dermatan or DS TAS Homo sapiens 58339 R-HSA-3656269 https://reactome.org/PathwayBrowser/#/R-HSA-3656269 Defective CHST6 does not transfer SO4(2-) to GlcNAc residues on keratan-PG TAS Homo sapiens 58339 R-HSA-6786012 https://reactome.org/PathwayBrowser/#/R-HSA-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins TAS Homo sapiens 58339 R-HSA-6786034 https://reactome.org/PathwayBrowser/#/R-HSA-6786034 CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin TAS Homo sapiens 58339 R-HSA-6786048 https://reactome.org/PathwayBrowser/#/R-HSA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 TAS Homo sapiens 58339 R-HSA-741449 https://reactome.org/PathwayBrowser/#/R-HSA-741449 SLC35B2,3 transport cytosolic PAPS to Golgi lumen TAS Homo sapiens 58339 R-HSA-8954262 https://reactome.org/PathwayBrowser/#/R-HSA-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 TAS Homo sapiens 58339 R-HSA-9668023 https://reactome.org/PathwayBrowser/#/R-HSA-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII TAS Homo sapiens 58339 R-HSA-9668148 https://reactome.org/PathwayBrowser/#/R-HSA-9668148 F8 variant is not sulfonated at Y1699 TAS Homo sapiens 58339 R-HSA-9753277 https://reactome.org/PathwayBrowser/#/R-HSA-9753277 SULT dimers sulfate APAP to APAP-SO3 TAS Homo sapiens 58339 R-HSA-9795134 https://reactome.org/PathwayBrowser/#/R-HSA-9795134 Cipro is sulfonated to sulfo-Cipro TAS Homo sapiens 58339 R-HSA-9844587 https://reactome.org/PathwayBrowser/#/R-HSA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer TAS Homo sapiens 58339 R-MMU-158468 https://reactome.org/PathwayBrowser/#/R-MMU-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Mus musculus 58339 R-MMU-158849 https://reactome.org/PathwayBrowser/#/R-MMU-158849 Phenol can form a sulfate conjugate IEA Mus musculus 58339 R-MMU-158860 https://reactome.org/PathwayBrowser/#/R-MMU-158860 SULT1A1 dimer sulfonates NHABP IEA Mus musculus 58339 R-MMU-159358 https://reactome.org/PathwayBrowser/#/R-MMU-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Mus musculus 58339 R-MMU-174389 https://reactome.org/PathwayBrowser/#/R-MMU-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Mus musculus 58339 R-MMU-176474 https://reactome.org/PathwayBrowser/#/R-MMU-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Mus musculus 58339 R-MMU-176494 https://reactome.org/PathwayBrowser/#/R-MMU-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Mus musculus 58339 R-MMU-176517 https://reactome.org/PathwayBrowser/#/R-MMU-176517 SULTs transfer (SO4)2- group to PREG IEA Mus musculus 58339 R-MMU-176521 https://reactome.org/PathwayBrowser/#/R-MMU-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Mus musculus 58339 R-MMU-176585 https://reactome.org/PathwayBrowser/#/R-MMU-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Mus musculus 58339 R-MMU-176588 https://reactome.org/PathwayBrowser/#/R-MMU-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Mus musculus 58339 R-MMU-176604 https://reactome.org/PathwayBrowser/#/R-MMU-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Mus musculus 58339 R-MMU-176609 https://reactome.org/PathwayBrowser/#/R-MMU-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Mus musculus 58339 R-MMU-176631 https://reactome.org/PathwayBrowser/#/R-MMU-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Mus musculus 58339 R-MMU-176646 https://reactome.org/PathwayBrowser/#/R-MMU-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Mus musculus 58339 R-MMU-176664 https://reactome.org/PathwayBrowser/#/R-MMU-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Mus musculus 58339 R-MMU-176669 https://reactome.org/PathwayBrowser/#/R-MMU-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Mus musculus 58339 R-MMU-1971483 https://reactome.org/PathwayBrowser/#/R-MMU-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Mus musculus 58339 R-MMU-2018659 https://reactome.org/PathwayBrowser/#/R-MMU-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Mus musculus 58339 R-MMU-2018682 https://reactome.org/PathwayBrowser/#/R-MMU-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Mus musculus 58339 R-MMU-2022061 https://reactome.org/PathwayBrowser/#/R-MMU-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Mus musculus 58339 R-MMU-2022063 https://reactome.org/PathwayBrowser/#/R-MMU-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Mus musculus 58339 R-MMU-2022860 https://reactome.org/PathwayBrowser/#/R-MMU-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Mus musculus 58339 R-MMU-2046175 https://reactome.org/PathwayBrowser/#/R-MMU-2046175 Further sulfation on galactose residues produces KSPG IEA Mus musculus 58339 R-MMU-2046222 https://reactome.org/PathwayBrowser/#/R-MMU-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Mus musculus 58339 R-MMU-2076383 https://reactome.org/PathwayBrowser/#/R-MMU-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Mus musculus 58339 R-MMU-2076419 https://reactome.org/PathwayBrowser/#/R-MMU-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Mus musculus 58339 R-MMU-2076508 https://reactome.org/PathwayBrowser/#/R-MMU-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Mus musculus 58339 R-MMU-2076611 https://reactome.org/PathwayBrowser/#/R-MMU-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Mus musculus 58339 R-MMU-6786012 https://reactome.org/PathwayBrowser/#/R-MMU-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Mus musculus 58339 R-MMU-6786034 https://reactome.org/PathwayBrowser/#/R-MMU-6786034 CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin IEA Mus musculus 58339 R-MMU-6786048 https://reactome.org/PathwayBrowser/#/R-MMU-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Mus musculus 58339 R-MMU-741449 https://reactome.org/PathwayBrowser/#/R-MMU-741449 SLC35B2,3 transport cytosolic PAPS to Golgi lumen IEA Mus musculus 58339 R-MMU-8954262 https://reactome.org/PathwayBrowser/#/R-MMU-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Mus musculus 58339 R-MMU-9668023 https://reactome.org/PathwayBrowser/#/R-MMU-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII IEA Mus musculus 58339 R-MMU-9753277 https://reactome.org/PathwayBrowser/#/R-MMU-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Mus musculus 58339 R-MMU-9844587 https://reactome.org/PathwayBrowser/#/R-MMU-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Mus musculus 58339 R-MTU-936583 https://reactome.org/PathwayBrowser/#/R-MTU-936583 APS is phosphorylated to PAPS TAS Mycobacterium tuberculosis 58339 R-MTU-936659 https://reactome.org/PathwayBrowser/#/R-MTU-936659 PAPS is dephosphorylated to APS TAS Mycobacterium tuberculosis 58339 R-RNO-158468 https://reactome.org/PathwayBrowser/#/R-RNO-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Rattus norvegicus 58339 R-RNO-158849 https://reactome.org/PathwayBrowser/#/R-RNO-158849 Phenol can form a sulfate conjugate IEA Rattus norvegicus 58339 R-RNO-158860 https://reactome.org/PathwayBrowser/#/R-RNO-158860 SULT1A1 dimer sulfonates NHABP IEA Rattus norvegicus 58339 R-RNO-159358 https://reactome.org/PathwayBrowser/#/R-RNO-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Rattus norvegicus 58339 R-RNO-174389 https://reactome.org/PathwayBrowser/#/R-RNO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Rattus norvegicus 58339 R-RNO-176474 https://reactome.org/PathwayBrowser/#/R-RNO-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Rattus norvegicus 58339 R-RNO-176494 https://reactome.org/PathwayBrowser/#/R-RNO-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Rattus norvegicus 58339 R-RNO-176517 https://reactome.org/PathwayBrowser/#/R-RNO-176517 SULTs transfer (SO4)2- group to PREG IEA Rattus norvegicus 58339 R-RNO-176521 https://reactome.org/PathwayBrowser/#/R-RNO-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Rattus norvegicus 58339 R-RNO-176585 https://reactome.org/PathwayBrowser/#/R-RNO-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Rattus norvegicus 58339 R-RNO-176588 https://reactome.org/PathwayBrowser/#/R-RNO-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Rattus norvegicus 58339 R-RNO-176604 https://reactome.org/PathwayBrowser/#/R-RNO-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Rattus norvegicus 58339 R-RNO-176609 https://reactome.org/PathwayBrowser/#/R-RNO-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Rattus norvegicus 58339 R-RNO-176631 https://reactome.org/PathwayBrowser/#/R-RNO-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Rattus norvegicus 58339 R-RNO-176646 https://reactome.org/PathwayBrowser/#/R-RNO-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Rattus norvegicus 58339 R-RNO-176664 https://reactome.org/PathwayBrowser/#/R-RNO-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Rattus norvegicus 58339 R-RNO-176669 https://reactome.org/PathwayBrowser/#/R-RNO-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Rattus norvegicus 58339 R-RNO-1971483 https://reactome.org/PathwayBrowser/#/R-RNO-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Rattus norvegicus 58339 R-RNO-2018659 https://reactome.org/PathwayBrowser/#/R-RNO-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Rattus norvegicus 58339 R-RNO-2018682 https://reactome.org/PathwayBrowser/#/R-RNO-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Rattus norvegicus 58339 R-RNO-2022061 https://reactome.org/PathwayBrowser/#/R-RNO-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Rattus norvegicus 58339 R-RNO-2022063 https://reactome.org/PathwayBrowser/#/R-RNO-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Rattus norvegicus 58339 R-RNO-2022860 https://reactome.org/PathwayBrowser/#/R-RNO-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Rattus norvegicus 58339 R-RNO-2046175 https://reactome.org/PathwayBrowser/#/R-RNO-2046175 Further sulfation on galactose residues produces KSPG IEA Rattus norvegicus 58339 R-RNO-2046222 https://reactome.org/PathwayBrowser/#/R-RNO-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Rattus norvegicus 58339 R-RNO-2076383 https://reactome.org/PathwayBrowser/#/R-RNO-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Rattus norvegicus 58339 R-RNO-2076419 https://reactome.org/PathwayBrowser/#/R-RNO-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Rattus norvegicus 58339 R-RNO-2076508 https://reactome.org/PathwayBrowser/#/R-RNO-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Rattus norvegicus 58339 R-RNO-2076611 https://reactome.org/PathwayBrowser/#/R-RNO-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Rattus norvegicus 58339 R-RNO-6786012 https://reactome.org/PathwayBrowser/#/R-RNO-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Rattus norvegicus 58339 R-RNO-6786048 https://reactome.org/PathwayBrowser/#/R-RNO-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Rattus norvegicus 58339 R-RNO-741449 https://reactome.org/PathwayBrowser/#/R-RNO-741449 SLC35B2,3 transport cytosolic PAPS to Golgi lumen IEA Rattus norvegicus 58339 R-RNO-8954262 https://reactome.org/PathwayBrowser/#/R-RNO-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Rattus norvegicus 58339 R-RNO-9668023 https://reactome.org/PathwayBrowser/#/R-RNO-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII IEA Rattus norvegicus 58339 R-RNO-9753277 https://reactome.org/PathwayBrowser/#/R-RNO-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Rattus norvegicus 58339 R-RNO-9844587 https://reactome.org/PathwayBrowser/#/R-RNO-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Rattus norvegicus 58339 R-SCE-174389 https://reactome.org/PathwayBrowser/#/R-SCE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Saccharomyces cerevisiae 58339 R-SPO-174389 https://reactome.org/PathwayBrowser/#/R-SPO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Schizosaccharomyces pombe 58339 R-SSC-158468 https://reactome.org/PathwayBrowser/#/R-SSC-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Sus scrofa 58339 R-SSC-158849 https://reactome.org/PathwayBrowser/#/R-SSC-158849 Phenol can form a sulfate conjugate IEA Sus scrofa 58339 R-SSC-158860 https://reactome.org/PathwayBrowser/#/R-SSC-158860 SULT1A1 dimer sulfonates NHABP IEA Sus scrofa 58339 R-SSC-159358 https://reactome.org/PathwayBrowser/#/R-SSC-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Sus scrofa 58339 R-SSC-174389 https://reactome.org/PathwayBrowser/#/R-SSC-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Sus scrofa 58339 R-SSC-176474 https://reactome.org/PathwayBrowser/#/R-SSC-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Sus scrofa 58339 R-SSC-176494 https://reactome.org/PathwayBrowser/#/R-SSC-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Sus scrofa 58339 R-SSC-176517 https://reactome.org/PathwayBrowser/#/R-SSC-176517 SULTs transfer (SO4)2- group to PREG IEA Sus scrofa 58339 R-SSC-176521 https://reactome.org/PathwayBrowser/#/R-SSC-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Sus scrofa 58339 R-SSC-176585 https://reactome.org/PathwayBrowser/#/R-SSC-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Sus scrofa 58339 R-SSC-176588 https://reactome.org/PathwayBrowser/#/R-SSC-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Sus scrofa 58339 R-SSC-176604 https://reactome.org/PathwayBrowser/#/R-SSC-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Sus scrofa 58339 R-SSC-176609 https://reactome.org/PathwayBrowser/#/R-SSC-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Sus scrofa 58339 R-SSC-176631 https://reactome.org/PathwayBrowser/#/R-SSC-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Sus scrofa 58339 R-SSC-176646 https://reactome.org/PathwayBrowser/#/R-SSC-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Sus scrofa 58339 R-SSC-176664 https://reactome.org/PathwayBrowser/#/R-SSC-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Sus scrofa 58339 R-SSC-176669 https://reactome.org/PathwayBrowser/#/R-SSC-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Sus scrofa 58339 R-SSC-1971483 https://reactome.org/PathwayBrowser/#/R-SSC-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Sus scrofa 58339 R-SSC-2018659 https://reactome.org/PathwayBrowser/#/R-SSC-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Sus scrofa 58339 R-SSC-2018682 https://reactome.org/PathwayBrowser/#/R-SSC-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Sus scrofa 58339 R-SSC-2022061 https://reactome.org/PathwayBrowser/#/R-SSC-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Sus scrofa 58339 R-SSC-2022063 https://reactome.org/PathwayBrowser/#/R-SSC-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Sus scrofa 58339 R-SSC-2022860 https://reactome.org/PathwayBrowser/#/R-SSC-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Sus scrofa 58339 R-SSC-2046175 https://reactome.org/PathwayBrowser/#/R-SSC-2046175 Further sulfation on galactose residues produces KSPG IEA Sus scrofa 58339 R-SSC-2046222 https://reactome.org/PathwayBrowser/#/R-SSC-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Sus scrofa 58339 R-SSC-2076383 https://reactome.org/PathwayBrowser/#/R-SSC-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Sus scrofa 58339 R-SSC-2076419 https://reactome.org/PathwayBrowser/#/R-SSC-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Sus scrofa 58339 R-SSC-2076508 https://reactome.org/PathwayBrowser/#/R-SSC-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Sus scrofa 58339 R-SSC-2076611 https://reactome.org/PathwayBrowser/#/R-SSC-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Sus scrofa 58339 R-SSC-6786012 https://reactome.org/PathwayBrowser/#/R-SSC-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Sus scrofa 58339 R-SSC-6786034 https://reactome.org/PathwayBrowser/#/R-SSC-6786034 CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin IEA Sus scrofa 58339 R-SSC-6786048 https://reactome.org/PathwayBrowser/#/R-SSC-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Sus scrofa 58339 R-SSC-741449 https://reactome.org/PathwayBrowser/#/R-SSC-741449 SLC35B2,3 transport cytosolic PAPS to Golgi lumen IEA Sus scrofa 58339 R-SSC-8954262 https://reactome.org/PathwayBrowser/#/R-SSC-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Sus scrofa 58339 R-SSC-9753277 https://reactome.org/PathwayBrowser/#/R-SSC-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Sus scrofa 58339 R-SSC-9844587 https://reactome.org/PathwayBrowser/#/R-SSC-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Sus scrofa 58339 R-XTR-158468 https://reactome.org/PathwayBrowser/#/R-XTR-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Xenopus tropicalis 58339 R-XTR-158849 https://reactome.org/PathwayBrowser/#/R-XTR-158849 Phenol can form a sulfate conjugate IEA Xenopus tropicalis 58339 R-XTR-158860 https://reactome.org/PathwayBrowser/#/R-XTR-158860 SULT1A1 dimer sulfonates NHABP IEA Xenopus tropicalis 58339 R-XTR-159358 https://reactome.org/PathwayBrowser/#/R-XTR-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Xenopus tropicalis 58339 R-XTR-174389 https://reactome.org/PathwayBrowser/#/R-XTR-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Xenopus tropicalis 58339 R-XTR-176474 https://reactome.org/PathwayBrowser/#/R-XTR-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Xenopus tropicalis 58339 R-XTR-176494 https://reactome.org/PathwayBrowser/#/R-XTR-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Xenopus tropicalis 58339 R-XTR-176517 https://reactome.org/PathwayBrowser/#/R-XTR-176517 SULTs transfer (SO4)2- group to PREG IEA Xenopus tropicalis 58339 R-XTR-176521 https://reactome.org/PathwayBrowser/#/R-XTR-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Xenopus tropicalis 58339 R-XTR-176585 https://reactome.org/PathwayBrowser/#/R-XTR-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Xenopus tropicalis 58339 R-XTR-176588 https://reactome.org/PathwayBrowser/#/R-XTR-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Xenopus tropicalis 58339 R-XTR-176604 https://reactome.org/PathwayBrowser/#/R-XTR-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Xenopus tropicalis 58339 R-XTR-176609 https://reactome.org/PathwayBrowser/#/R-XTR-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Xenopus tropicalis 58339 R-XTR-176631 https://reactome.org/PathwayBrowser/#/R-XTR-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Xenopus tropicalis 58339 R-XTR-176646 https://reactome.org/PathwayBrowser/#/R-XTR-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Xenopus tropicalis 58339 R-XTR-176664 https://reactome.org/PathwayBrowser/#/R-XTR-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Xenopus tropicalis 58339 R-XTR-176669 https://reactome.org/PathwayBrowser/#/R-XTR-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Xenopus tropicalis 58339 R-XTR-1971483 https://reactome.org/PathwayBrowser/#/R-XTR-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Xenopus tropicalis 58339 R-XTR-2018659 https://reactome.org/PathwayBrowser/#/R-XTR-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Xenopus tropicalis 58339 R-XTR-2018682 https://reactome.org/PathwayBrowser/#/R-XTR-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Xenopus tropicalis 58339 R-XTR-2022063 https://reactome.org/PathwayBrowser/#/R-XTR-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Xenopus tropicalis 58339 R-XTR-2022860 https://reactome.org/PathwayBrowser/#/R-XTR-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Xenopus tropicalis 58339 R-XTR-2046175 https://reactome.org/PathwayBrowser/#/R-XTR-2046175 Further sulfation on galactose residues produces KSPG IEA Xenopus tropicalis 58339 R-XTR-2046222 https://reactome.org/PathwayBrowser/#/R-XTR-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Xenopus tropicalis 58339 R-XTR-2076383 https://reactome.org/PathwayBrowser/#/R-XTR-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Xenopus tropicalis 58339 R-XTR-2076419 https://reactome.org/PathwayBrowser/#/R-XTR-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Xenopus tropicalis 58339 R-XTR-2076508 https://reactome.org/PathwayBrowser/#/R-XTR-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Xenopus tropicalis 58339 R-XTR-2076611 https://reactome.org/PathwayBrowser/#/R-XTR-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Xenopus tropicalis 58339 R-XTR-6786012 https://reactome.org/PathwayBrowser/#/R-XTR-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Xenopus tropicalis 58339 R-XTR-8954262 https://reactome.org/PathwayBrowser/#/R-XTR-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Xenopus tropicalis 58339 R-XTR-9753277 https://reactome.org/PathwayBrowser/#/R-XTR-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Xenopus tropicalis 58339 R-XTR-9844587 https://reactome.org/PathwayBrowser/#/R-XTR-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Xenopus tropicalis 58343 R-BTA-158468 https://reactome.org/PathwayBrowser/#/R-BTA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Bos taurus 58343 R-BTA-158849 https://reactome.org/PathwayBrowser/#/R-BTA-158849 Phenol can form a sulfate conjugate IEA Bos taurus 58343 R-BTA-158860 https://reactome.org/PathwayBrowser/#/R-BTA-158860 SULT1A1 dimer sulfonates NHABP IEA Bos taurus 58343 R-BTA-159358 https://reactome.org/PathwayBrowser/#/R-BTA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Bos taurus 58343 R-BTA-176474 https://reactome.org/PathwayBrowser/#/R-BTA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Bos taurus 58343 R-BTA-176494 https://reactome.org/PathwayBrowser/#/R-BTA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Bos taurus 58343 R-BTA-176517 https://reactome.org/PathwayBrowser/#/R-BTA-176517 SULTs transfer (SO4)2- group to PREG IEA Bos taurus 58343 R-BTA-176521 https://reactome.org/PathwayBrowser/#/R-BTA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Bos taurus 58343 R-BTA-176585 https://reactome.org/PathwayBrowser/#/R-BTA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Bos taurus 58343 R-BTA-176588 https://reactome.org/PathwayBrowser/#/R-BTA-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Bos taurus 58343 R-BTA-176604 https://reactome.org/PathwayBrowser/#/R-BTA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Bos taurus 58343 R-BTA-176606 https://reactome.org/PathwayBrowser/#/R-BTA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Bos taurus 58343 R-BTA-176609 https://reactome.org/PathwayBrowser/#/R-BTA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Bos taurus 58343 R-BTA-176631 https://reactome.org/PathwayBrowser/#/R-BTA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Bos taurus 58343 R-BTA-176646 https://reactome.org/PathwayBrowser/#/R-BTA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Bos taurus 58343 R-BTA-176664 https://reactome.org/PathwayBrowser/#/R-BTA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Bos taurus 58343 R-BTA-176669 https://reactome.org/PathwayBrowser/#/R-BTA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Bos taurus 58343 R-BTA-1971483 https://reactome.org/PathwayBrowser/#/R-BTA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Bos taurus 58343 R-BTA-199202 https://reactome.org/PathwayBrowser/#/R-BTA-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Bos taurus 58343 R-BTA-2018659 https://reactome.org/PathwayBrowser/#/R-BTA-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Bos taurus 58343 R-BTA-2018682 https://reactome.org/PathwayBrowser/#/R-BTA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Bos taurus 58343 R-BTA-2022061 https://reactome.org/PathwayBrowser/#/R-BTA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Bos taurus 58343 R-BTA-2022063 https://reactome.org/PathwayBrowser/#/R-BTA-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Bos taurus 58343 R-BTA-2022860 https://reactome.org/PathwayBrowser/#/R-BTA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Bos taurus 58343 R-BTA-2046175 https://reactome.org/PathwayBrowser/#/R-BTA-2046175 Further sulfation on galactose residues produces KSPG IEA Bos taurus 58343 R-BTA-2046222 https://reactome.org/PathwayBrowser/#/R-BTA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Bos taurus 58343 R-BTA-2076383 https://reactome.org/PathwayBrowser/#/R-BTA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Bos taurus 58343 R-BTA-2076419 https://reactome.org/PathwayBrowser/#/R-BTA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Bos taurus 58343 R-BTA-2076508 https://reactome.org/PathwayBrowser/#/R-BTA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Bos taurus 58343 R-BTA-2076611 https://reactome.org/PathwayBrowser/#/R-BTA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Bos taurus 58343 R-BTA-6786012 https://reactome.org/PathwayBrowser/#/R-BTA-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Bos taurus 58343 R-BTA-6786034 https://reactome.org/PathwayBrowser/#/R-BTA-6786034 CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin IEA Bos taurus 58343 R-BTA-6786048 https://reactome.org/PathwayBrowser/#/R-BTA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Bos taurus 58343 R-BTA-8953499 https://reactome.org/PathwayBrowser/#/R-BTA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Bos taurus 58343 R-BTA-8954262 https://reactome.org/PathwayBrowser/#/R-BTA-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Bos taurus 58343 R-BTA-9668023 https://reactome.org/PathwayBrowser/#/R-BTA-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII IEA Bos taurus 58343 R-BTA-9753277 https://reactome.org/PathwayBrowser/#/R-BTA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Bos taurus 58343 R-BTA-9844587 https://reactome.org/PathwayBrowser/#/R-BTA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Bos taurus 58343 R-CEL-176474 https://reactome.org/PathwayBrowser/#/R-CEL-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Caenorhabditis elegans 58343 R-CEL-176585 https://reactome.org/PathwayBrowser/#/R-CEL-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Caenorhabditis elegans 58343 R-CEL-176606 https://reactome.org/PathwayBrowser/#/R-CEL-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Caenorhabditis elegans 58343 R-CEL-199202 https://reactome.org/PathwayBrowser/#/R-CEL-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Caenorhabditis elegans 58343 R-CEL-2022860 https://reactome.org/PathwayBrowser/#/R-CEL-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Caenorhabditis elegans 58343 R-CEL-2076383 https://reactome.org/PathwayBrowser/#/R-CEL-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Caenorhabditis elegans 58343 R-CEL-2076419 https://reactome.org/PathwayBrowser/#/R-CEL-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Caenorhabditis elegans 58343 R-CEL-2076508 https://reactome.org/PathwayBrowser/#/R-CEL-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Caenorhabditis elegans 58343 R-CEL-2076611 https://reactome.org/PathwayBrowser/#/R-CEL-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Caenorhabditis elegans 58343 R-CEL-8953499 https://reactome.org/PathwayBrowser/#/R-CEL-8953499 IMPAD1 hydrolyses PAP to AMP IEA Caenorhabditis elegans 58343 R-CFA-158468 https://reactome.org/PathwayBrowser/#/R-CFA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Canis familiaris 58343 R-CFA-158849 https://reactome.org/PathwayBrowser/#/R-CFA-158849 Phenol can form a sulfate conjugate IEA Canis familiaris 58343 R-CFA-158860 https://reactome.org/PathwayBrowser/#/R-CFA-158860 SULT1A1 dimer sulfonates NHABP IEA Canis familiaris 58343 R-CFA-159358 https://reactome.org/PathwayBrowser/#/R-CFA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Canis familiaris 58343 R-CFA-176474 https://reactome.org/PathwayBrowser/#/R-CFA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Canis familiaris 58343 R-CFA-176494 https://reactome.org/PathwayBrowser/#/R-CFA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Canis familiaris 58343 R-CFA-176517 https://reactome.org/PathwayBrowser/#/R-CFA-176517 SULTs transfer (SO4)2- group to PREG IEA Canis familiaris 58343 R-CFA-176521 https://reactome.org/PathwayBrowser/#/R-CFA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Canis familiaris 58343 R-CFA-176585 https://reactome.org/PathwayBrowser/#/R-CFA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Canis familiaris 58343 R-CFA-176606 https://reactome.org/PathwayBrowser/#/R-CFA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Canis familiaris 58343 R-CFA-176609 https://reactome.org/PathwayBrowser/#/R-CFA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Canis familiaris 58343 R-CFA-176631 https://reactome.org/PathwayBrowser/#/R-CFA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Canis familiaris 58343 R-CFA-176646 https://reactome.org/PathwayBrowser/#/R-CFA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Canis familiaris 58343 R-CFA-176664 https://reactome.org/PathwayBrowser/#/R-CFA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Canis familiaris 58343 R-CFA-176669 https://reactome.org/PathwayBrowser/#/R-CFA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Canis familiaris 58343 R-CFA-1971483 https://reactome.org/PathwayBrowser/#/R-CFA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Canis familiaris 58343 R-CFA-199202 https://reactome.org/PathwayBrowser/#/R-CFA-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Canis familiaris 58343 R-CFA-2018682 https://reactome.org/PathwayBrowser/#/R-CFA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Canis familiaris 58343 R-CFA-2022061 https://reactome.org/PathwayBrowser/#/R-CFA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Canis familiaris 58343 R-CFA-2022860 https://reactome.org/PathwayBrowser/#/R-CFA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Canis familiaris 58343 R-CFA-2046175 https://reactome.org/PathwayBrowser/#/R-CFA-2046175 Further sulfation on galactose residues produces KSPG IEA Canis familiaris 58343 R-CFA-2046222 https://reactome.org/PathwayBrowser/#/R-CFA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Canis familiaris 58343 R-CFA-2076383 https://reactome.org/PathwayBrowser/#/R-CFA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Canis familiaris 58343 R-CFA-2076419 https://reactome.org/PathwayBrowser/#/R-CFA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Canis familiaris 58343 R-CFA-2076508 https://reactome.org/PathwayBrowser/#/R-CFA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Canis familiaris 58343 R-CFA-2076611 https://reactome.org/PathwayBrowser/#/R-CFA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Canis familiaris 58343 R-CFA-6786012 https://reactome.org/PathwayBrowser/#/R-CFA-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Canis familiaris 58343 R-CFA-6786048 https://reactome.org/PathwayBrowser/#/R-CFA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Canis familiaris 58343 R-CFA-8953499 https://reactome.org/PathwayBrowser/#/R-CFA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Canis familiaris 58343 R-CFA-8954262 https://reactome.org/PathwayBrowser/#/R-CFA-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Canis familiaris 58343 R-CFA-9753277 https://reactome.org/PathwayBrowser/#/R-CFA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Canis familiaris 58343 R-DDI-176606 https://reactome.org/PathwayBrowser/#/R-DDI-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Dictyostelium discoideum 58343 R-DDI-199202 https://reactome.org/PathwayBrowser/#/R-DDI-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Dictyostelium discoideum 58343 R-DDI-8953499 https://reactome.org/PathwayBrowser/#/R-DDI-8953499 IMPAD1 hydrolyses PAP to AMP IEA Dictyostelium discoideum 58343 R-DME-158468 https://reactome.org/PathwayBrowser/#/R-DME-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Drosophila melanogaster 58343 R-DME-158849 https://reactome.org/PathwayBrowser/#/R-DME-158849 Phenol can form a sulfate conjugate IEA Drosophila melanogaster 58343 R-DME-158860 https://reactome.org/PathwayBrowser/#/R-DME-158860 SULT1A1 dimer sulfonates NHABP IEA Drosophila melanogaster 58343 R-DME-159358 https://reactome.org/PathwayBrowser/#/R-DME-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Drosophila melanogaster 58343 R-DME-176474 https://reactome.org/PathwayBrowser/#/R-DME-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Drosophila melanogaster 58343 R-DME-176494 https://reactome.org/PathwayBrowser/#/R-DME-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Drosophila melanogaster 58343 R-DME-176517 https://reactome.org/PathwayBrowser/#/R-DME-176517 SULTs transfer (SO4)2- group to PREG IEA Drosophila melanogaster 58343 R-DME-176521 https://reactome.org/PathwayBrowser/#/R-DME-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Drosophila melanogaster 58343 R-DME-176585 https://reactome.org/PathwayBrowser/#/R-DME-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Drosophila melanogaster 58343 R-DME-176588 https://reactome.org/PathwayBrowser/#/R-DME-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Drosophila melanogaster 58343 R-DME-176604 https://reactome.org/PathwayBrowser/#/R-DME-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Drosophila melanogaster 58343 R-DME-176606 https://reactome.org/PathwayBrowser/#/R-DME-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Drosophila melanogaster 58343 R-DME-176609 https://reactome.org/PathwayBrowser/#/R-DME-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Drosophila melanogaster 58343 R-DME-176631 https://reactome.org/PathwayBrowser/#/R-DME-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Drosophila melanogaster 58343 R-DME-176646 https://reactome.org/PathwayBrowser/#/R-DME-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Drosophila melanogaster 58343 R-DME-176664 https://reactome.org/PathwayBrowser/#/R-DME-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Drosophila melanogaster 58343 R-DME-176669 https://reactome.org/PathwayBrowser/#/R-DME-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Drosophila melanogaster 58343 R-DME-1971483 https://reactome.org/PathwayBrowser/#/R-DME-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Drosophila melanogaster 58343 R-DME-199202 https://reactome.org/PathwayBrowser/#/R-DME-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Drosophila melanogaster 58343 R-DME-2018682 https://reactome.org/PathwayBrowser/#/R-DME-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Drosophila melanogaster 58343 R-DME-2022061 https://reactome.org/PathwayBrowser/#/R-DME-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Drosophila melanogaster 58343 R-DME-2022860 https://reactome.org/PathwayBrowser/#/R-DME-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Drosophila melanogaster 58343 R-DME-2046175 https://reactome.org/PathwayBrowser/#/R-DME-2046175 Further sulfation on galactose residues produces KSPG IEA Drosophila melanogaster 58343 R-DME-2046222 https://reactome.org/PathwayBrowser/#/R-DME-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Drosophila melanogaster 58343 R-DME-2076383 https://reactome.org/PathwayBrowser/#/R-DME-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Drosophila melanogaster 58343 R-DME-2076419 https://reactome.org/PathwayBrowser/#/R-DME-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Drosophila melanogaster 58343 R-DME-2076508 https://reactome.org/PathwayBrowser/#/R-DME-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Drosophila melanogaster 58343 R-DME-2076611 https://reactome.org/PathwayBrowser/#/R-DME-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Drosophila melanogaster 58343 R-DME-6786012 https://reactome.org/PathwayBrowser/#/R-DME-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Drosophila melanogaster 58343 R-DME-6786048 https://reactome.org/PathwayBrowser/#/R-DME-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Drosophila melanogaster 58343 R-DME-8953499 https://reactome.org/PathwayBrowser/#/R-DME-8953499 IMPAD1 hydrolyses PAP to AMP IEA Drosophila melanogaster 58343 R-DME-9753277 https://reactome.org/PathwayBrowser/#/R-DME-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Drosophila melanogaster 58343 R-DRE-158468 https://reactome.org/PathwayBrowser/#/R-DRE-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Danio rerio 58343 R-DRE-158849 https://reactome.org/PathwayBrowser/#/R-DRE-158849 Phenol can form a sulfate conjugate IEA Danio rerio 58343 R-DRE-158860 https://reactome.org/PathwayBrowser/#/R-DRE-158860 SULT1A1 dimer sulfonates NHABP IEA Danio rerio 58343 R-DRE-159358 https://reactome.org/PathwayBrowser/#/R-DRE-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Danio rerio 58343 R-DRE-176474 https://reactome.org/PathwayBrowser/#/R-DRE-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Danio rerio 58343 R-DRE-176494 https://reactome.org/PathwayBrowser/#/R-DRE-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Danio rerio 58343 R-DRE-176517 https://reactome.org/PathwayBrowser/#/R-DRE-176517 SULTs transfer (SO4)2- group to PREG IEA Danio rerio 58343 R-DRE-176521 https://reactome.org/PathwayBrowser/#/R-DRE-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Danio rerio 58343 R-DRE-176585 https://reactome.org/PathwayBrowser/#/R-DRE-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Danio rerio 58343 R-DRE-176588 https://reactome.org/PathwayBrowser/#/R-DRE-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Danio rerio 58343 R-DRE-176604 https://reactome.org/PathwayBrowser/#/R-DRE-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Danio rerio 58343 R-DRE-176609 https://reactome.org/PathwayBrowser/#/R-DRE-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Danio rerio 58343 R-DRE-176631 https://reactome.org/PathwayBrowser/#/R-DRE-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Danio rerio 58343 R-DRE-176646 https://reactome.org/PathwayBrowser/#/R-DRE-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Danio rerio 58343 R-DRE-176664 https://reactome.org/PathwayBrowser/#/R-DRE-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Danio rerio 58343 R-DRE-176669 https://reactome.org/PathwayBrowser/#/R-DRE-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Danio rerio 58343 R-DRE-1971483 https://reactome.org/PathwayBrowser/#/R-DRE-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Danio rerio 58343 R-DRE-2018659 https://reactome.org/PathwayBrowser/#/R-DRE-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Danio rerio 58343 R-DRE-2018682 https://reactome.org/PathwayBrowser/#/R-DRE-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Danio rerio 58343 R-DRE-2022063 https://reactome.org/PathwayBrowser/#/R-DRE-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Danio rerio 58343 R-DRE-2022860 https://reactome.org/PathwayBrowser/#/R-DRE-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Danio rerio 58343 R-DRE-2046175 https://reactome.org/PathwayBrowser/#/R-DRE-2046175 Further sulfation on galactose residues produces KSPG IEA Danio rerio 58343 R-DRE-2076419 https://reactome.org/PathwayBrowser/#/R-DRE-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Danio rerio 58343 R-DRE-2076508 https://reactome.org/PathwayBrowser/#/R-DRE-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Danio rerio 58343 R-DRE-2076611 https://reactome.org/PathwayBrowser/#/R-DRE-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Danio rerio 58343 R-DRE-6786048 https://reactome.org/PathwayBrowser/#/R-DRE-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Danio rerio 58343 R-DRE-8953499 https://reactome.org/PathwayBrowser/#/R-DRE-8953499 IMPAD1 hydrolyses PAP to AMP IEA Danio rerio 58343 R-DRE-9753277 https://reactome.org/PathwayBrowser/#/R-DRE-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Danio rerio 58343 R-DRE-9844587 https://reactome.org/PathwayBrowser/#/R-DRE-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Danio rerio 58343 R-GGA-158468 https://reactome.org/PathwayBrowser/#/R-GGA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Gallus gallus 58343 R-GGA-158849 https://reactome.org/PathwayBrowser/#/R-GGA-158849 Phenol can form a sulfate conjugate IEA Gallus gallus 58343 R-GGA-158860 https://reactome.org/PathwayBrowser/#/R-GGA-158860 SULT1A1 dimer sulfonates NHABP IEA Gallus gallus 58343 R-GGA-159358 https://reactome.org/PathwayBrowser/#/R-GGA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Gallus gallus 58343 R-GGA-176474 https://reactome.org/PathwayBrowser/#/R-GGA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Gallus gallus 58343 R-GGA-176494 https://reactome.org/PathwayBrowser/#/R-GGA-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Gallus gallus 58343 R-GGA-176517 https://reactome.org/PathwayBrowser/#/R-GGA-176517 SULTs transfer (SO4)2- group to PREG IEA Gallus gallus 58343 R-GGA-176521 https://reactome.org/PathwayBrowser/#/R-GGA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Gallus gallus 58343 R-GGA-176585 https://reactome.org/PathwayBrowser/#/R-GGA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Gallus gallus 58343 R-GGA-176588 https://reactome.org/PathwayBrowser/#/R-GGA-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Gallus gallus 58343 R-GGA-176604 https://reactome.org/PathwayBrowser/#/R-GGA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Gallus gallus 58343 R-GGA-176606 https://reactome.org/PathwayBrowser/#/R-GGA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Gallus gallus 58343 R-GGA-176609 https://reactome.org/PathwayBrowser/#/R-GGA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Gallus gallus 58343 R-GGA-176631 https://reactome.org/PathwayBrowser/#/R-GGA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Gallus gallus 58343 R-GGA-176646 https://reactome.org/PathwayBrowser/#/R-GGA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Gallus gallus 58343 R-GGA-176664 https://reactome.org/PathwayBrowser/#/R-GGA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Gallus gallus 58343 R-GGA-176669 https://reactome.org/PathwayBrowser/#/R-GGA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Gallus gallus 58343 R-GGA-1971483 https://reactome.org/PathwayBrowser/#/R-GGA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Gallus gallus 58343 R-GGA-199202 https://reactome.org/PathwayBrowser/#/R-GGA-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Gallus gallus 58343 R-GGA-2018659 https://reactome.org/PathwayBrowser/#/R-GGA-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Gallus gallus 58343 R-GGA-2018682 https://reactome.org/PathwayBrowser/#/R-GGA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Gallus gallus 58343 R-GGA-2022061 https://reactome.org/PathwayBrowser/#/R-GGA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Gallus gallus 58343 R-GGA-2022063 https://reactome.org/PathwayBrowser/#/R-GGA-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Gallus gallus 58343 R-GGA-2022860 https://reactome.org/PathwayBrowser/#/R-GGA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Gallus gallus 58343 R-GGA-2046175 https://reactome.org/PathwayBrowser/#/R-GGA-2046175 Further sulfation on galactose residues produces KSPG IEA Gallus gallus 58343 R-GGA-2046222 https://reactome.org/PathwayBrowser/#/R-GGA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Gallus gallus 58343 R-GGA-2076383 https://reactome.org/PathwayBrowser/#/R-GGA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Gallus gallus 58343 R-GGA-2076419 https://reactome.org/PathwayBrowser/#/R-GGA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Gallus gallus 58343 R-GGA-2076508 https://reactome.org/PathwayBrowser/#/R-GGA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Gallus gallus 58343 R-GGA-2076611 https://reactome.org/PathwayBrowser/#/R-GGA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Gallus gallus 58343 R-GGA-6786012 https://reactome.org/PathwayBrowser/#/R-GGA-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Gallus gallus 58343 R-GGA-6786048 https://reactome.org/PathwayBrowser/#/R-GGA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Gallus gallus 58343 R-GGA-8954262 https://reactome.org/PathwayBrowser/#/R-GGA-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Gallus gallus 58343 R-GGA-9668023 https://reactome.org/PathwayBrowser/#/R-GGA-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII IEA Gallus gallus 58343 R-GGA-9753277 https://reactome.org/PathwayBrowser/#/R-GGA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Gallus gallus 58343 R-GGA-9844587 https://reactome.org/PathwayBrowser/#/R-GGA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Gallus gallus 58343 R-HSA-158468 https://reactome.org/PathwayBrowser/#/R-HSA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 TAS Homo sapiens 58343 R-HSA-158849 https://reactome.org/PathwayBrowser/#/R-HSA-158849 Phenol can form a sulfate conjugate TAS Homo sapiens 58343 R-HSA-158860 https://reactome.org/PathwayBrowser/#/R-HSA-158860 SULT1A1 dimer sulfonates NHABP TAS Homo sapiens 58343 R-HSA-159358 https://reactome.org/PathwayBrowser/#/R-HSA-159358 SULT1A3,4 dimers sulfate DA to DAOS TAS Homo sapiens 58343 R-HSA-176474 https://reactome.org/PathwayBrowser/#/R-HSA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP TAS Homo sapiens 58343 R-HSA-176494 https://reactome.org/PathwayBrowser/#/R-HSA-176494 SULTs transfer (SO4)2- group to 27HCHOL TAS Homo sapiens 58343 R-HSA-176517 https://reactome.org/PathwayBrowser/#/R-HSA-176517 SULTs transfer (SO4)2- group to PREG TAS Homo sapiens 58343 R-HSA-176521 https://reactome.org/PathwayBrowser/#/R-HSA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP TAS Homo sapiens 58343 R-HSA-176585 https://reactome.org/PathwayBrowser/#/R-HSA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP TAS Homo sapiens 58343 R-HSA-176588 https://reactome.org/PathwayBrowser/#/R-HSA-176588 lithocholate + PAPS => lithocholate sulfate + PAP TAS Homo sapiens 58343 R-HSA-176604 https://reactome.org/PathwayBrowser/#/R-HSA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP TAS Homo sapiens 58343 R-HSA-176606 https://reactome.org/PathwayBrowser/#/R-HSA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate TAS Homo sapiens 58343 R-HSA-176609 https://reactome.org/PathwayBrowser/#/R-HSA-176609 cholesterol + PAPS => cholesterol sulfate + PAP TAS Homo sapiens 58343 R-HSA-176631 https://reactome.org/PathwayBrowser/#/R-HSA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP TAS Homo sapiens 58343 R-HSA-176646 https://reactome.org/PathwayBrowser/#/R-HSA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP TAS Homo sapiens 58343 R-HSA-176664 https://reactome.org/PathwayBrowser/#/R-HSA-176664 estrone + PAPS => estrone 3-sulfate + PAP TAS Homo sapiens 58343 R-HSA-176669 https://reactome.org/PathwayBrowser/#/R-HSA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP TAS Homo sapiens 58343 R-HSA-1971483 https://reactome.org/PathwayBrowser/#/R-HSA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 TAS Homo sapiens 58343 R-HSA-199202 https://reactome.org/PathwayBrowser/#/R-HSA-199202 Phosphopantetheine conjugation of the ACP domain of FAS TAS Homo sapiens 58343 R-HSA-2018659 https://reactome.org/PathwayBrowser/#/R-HSA-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 TAS Homo sapiens 58343 R-HSA-2018682 https://reactome.org/PathwayBrowser/#/R-HSA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains TAS Homo sapiens 58343 R-HSA-2022061 https://reactome.org/PathwayBrowser/#/R-HSA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate TAS Homo sapiens 58343 R-HSA-2022063 https://reactome.org/PathwayBrowser/#/R-HSA-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS TAS Homo sapiens 58343 R-HSA-2022860 https://reactome.org/PathwayBrowser/#/R-HSA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) TAS Homo sapiens 58343 R-HSA-2046175 https://reactome.org/PathwayBrowser/#/R-HSA-2046175 Further sulfation on galactose residues produces KSPG TAS Homo sapiens 58343 R-HSA-2046222 https://reactome.org/PathwayBrowser/#/R-HSA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG TAS Homo sapiens 58343 R-HSA-2076383 https://reactome.org/PathwayBrowser/#/R-HSA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate TAS Homo sapiens 58343 R-HSA-2076419 https://reactome.org/PathwayBrowser/#/R-HSA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin TAS Homo sapiens 58343 R-HSA-2076508 https://reactome.org/PathwayBrowser/#/R-HSA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate TAS Homo sapiens 58343 R-HSA-2076611 https://reactome.org/PathwayBrowser/#/R-HSA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate TAS Homo sapiens 58343 R-HSA-2408548 https://reactome.org/PathwayBrowser/#/R-HSA-2408548 PAPSe is reduced to SeO3(2-) by PAPSe reductase IEA Homo sapiens 58343 R-HSA-6786012 https://reactome.org/PathwayBrowser/#/R-HSA-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins TAS Homo sapiens 58343 R-HSA-6786034 https://reactome.org/PathwayBrowser/#/R-HSA-6786034 CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin TAS Homo sapiens 58343 R-HSA-6786048 https://reactome.org/PathwayBrowser/#/R-HSA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 TAS Homo sapiens 58343 R-HSA-8938314 https://reactome.org/PathwayBrowser/#/R-HSA-8938314 ENPPs hydrolyse CoA-SH to PPANT, PAP TAS Homo sapiens 58343 R-HSA-8953499 https://reactome.org/PathwayBrowser/#/R-HSA-8953499 IMPAD1 hydrolyses PAP to AMP TAS Homo sapiens 58343 R-HSA-8954262 https://reactome.org/PathwayBrowser/#/R-HSA-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 TAS Homo sapiens 58343 R-HSA-9668023 https://reactome.org/PathwayBrowser/#/R-HSA-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII TAS Homo sapiens 58343 R-HSA-9753277 https://reactome.org/PathwayBrowser/#/R-HSA-9753277 SULT dimers sulfate APAP to APAP-SO3 TAS Homo sapiens 58343 R-HSA-9795134 https://reactome.org/PathwayBrowser/#/R-HSA-9795134 Cipro is sulfonated to sulfo-Cipro TAS Homo sapiens 58343 R-HSA-9837354 https://reactome.org/PathwayBrowser/#/R-HSA-9837354 NUDT8 hydrolyzes CoA-SH to PPANT IEA Homo sapiens 58343 R-HSA-9844587 https://reactome.org/PathwayBrowser/#/R-HSA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer TAS Homo sapiens 58343 R-MMU-158468 https://reactome.org/PathwayBrowser/#/R-MMU-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Mus musculus 58343 R-MMU-158849 https://reactome.org/PathwayBrowser/#/R-MMU-158849 Phenol can form a sulfate conjugate IEA Mus musculus 58343 R-MMU-158860 https://reactome.org/PathwayBrowser/#/R-MMU-158860 SULT1A1 dimer sulfonates NHABP IEA Mus musculus 58343 R-MMU-159358 https://reactome.org/PathwayBrowser/#/R-MMU-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Mus musculus 58343 R-MMU-176474 https://reactome.org/PathwayBrowser/#/R-MMU-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Mus musculus 58343 R-MMU-176494 https://reactome.org/PathwayBrowser/#/R-MMU-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Mus musculus 58343 R-MMU-176517 https://reactome.org/PathwayBrowser/#/R-MMU-176517 SULTs transfer (SO4)2- group to PREG IEA Mus musculus 58343 R-MMU-176521 https://reactome.org/PathwayBrowser/#/R-MMU-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Mus musculus 58343 R-MMU-176585 https://reactome.org/PathwayBrowser/#/R-MMU-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Mus musculus 58343 R-MMU-176588 https://reactome.org/PathwayBrowser/#/R-MMU-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Mus musculus 58343 R-MMU-176604 https://reactome.org/PathwayBrowser/#/R-MMU-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Mus musculus 58343 R-MMU-176606 https://reactome.org/PathwayBrowser/#/R-MMU-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Mus musculus 58343 R-MMU-176609 https://reactome.org/PathwayBrowser/#/R-MMU-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Mus musculus 58343 R-MMU-176631 https://reactome.org/PathwayBrowser/#/R-MMU-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Mus musculus 58343 R-MMU-176646 https://reactome.org/PathwayBrowser/#/R-MMU-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Mus musculus 58343 R-MMU-176664 https://reactome.org/PathwayBrowser/#/R-MMU-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Mus musculus 58343 R-MMU-176669 https://reactome.org/PathwayBrowser/#/R-MMU-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Mus musculus 58343 R-MMU-1971483 https://reactome.org/PathwayBrowser/#/R-MMU-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Mus musculus 58343 R-MMU-199202 https://reactome.org/PathwayBrowser/#/R-MMU-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Mus musculus 58343 R-MMU-2018659 https://reactome.org/PathwayBrowser/#/R-MMU-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Mus musculus 58343 R-MMU-2018682 https://reactome.org/PathwayBrowser/#/R-MMU-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Mus musculus 58343 R-MMU-2022061 https://reactome.org/PathwayBrowser/#/R-MMU-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Mus musculus 58343 R-MMU-2022063 https://reactome.org/PathwayBrowser/#/R-MMU-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Mus musculus 58343 R-MMU-2022860 https://reactome.org/PathwayBrowser/#/R-MMU-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Mus musculus 58343 R-MMU-2046175 https://reactome.org/PathwayBrowser/#/R-MMU-2046175 Further sulfation on galactose residues produces KSPG IEA Mus musculus 58343 R-MMU-2046222 https://reactome.org/PathwayBrowser/#/R-MMU-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Mus musculus 58343 R-MMU-2076383 https://reactome.org/PathwayBrowser/#/R-MMU-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Mus musculus 58343 R-MMU-2076419 https://reactome.org/PathwayBrowser/#/R-MMU-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Mus musculus 58343 R-MMU-2076508 https://reactome.org/PathwayBrowser/#/R-MMU-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Mus musculus 58343 R-MMU-2076611 https://reactome.org/PathwayBrowser/#/R-MMU-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Mus musculus 58343 R-MMU-6786012 https://reactome.org/PathwayBrowser/#/R-MMU-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Mus musculus 58343 R-MMU-6786034 https://reactome.org/PathwayBrowser/#/R-MMU-6786034 CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin IEA Mus musculus 58343 R-MMU-6786048 https://reactome.org/PathwayBrowser/#/R-MMU-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Mus musculus 58343 R-MMU-8953499 https://reactome.org/PathwayBrowser/#/R-MMU-8953499 IMPAD1 hydrolyses PAP to AMP IEA Mus musculus 58343 R-MMU-8954262 https://reactome.org/PathwayBrowser/#/R-MMU-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Mus musculus 58343 R-MMU-9668023 https://reactome.org/PathwayBrowser/#/R-MMU-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII IEA Mus musculus 58343 R-MMU-9753277 https://reactome.org/PathwayBrowser/#/R-MMU-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Mus musculus 58343 R-MMU-9837342 https://reactome.org/PathwayBrowser/#/R-MMU-9837342 Nudt8 hydrolyzes CoA-SH to PPANT TAS Mus musculus 58343 R-MMU-9844587 https://reactome.org/PathwayBrowser/#/R-MMU-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Mus musculus 58343 R-RNO-158468 https://reactome.org/PathwayBrowser/#/R-RNO-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Rattus norvegicus 58343 R-RNO-158849 https://reactome.org/PathwayBrowser/#/R-RNO-158849 Phenol can form a sulfate conjugate IEA Rattus norvegicus 58343 R-RNO-158860 https://reactome.org/PathwayBrowser/#/R-RNO-158860 SULT1A1 dimer sulfonates NHABP IEA Rattus norvegicus 58343 R-RNO-159358 https://reactome.org/PathwayBrowser/#/R-RNO-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Rattus norvegicus 58343 R-RNO-176474 https://reactome.org/PathwayBrowser/#/R-RNO-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Rattus norvegicus 58343 R-RNO-176494 https://reactome.org/PathwayBrowser/#/R-RNO-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Rattus norvegicus 58343 R-RNO-176517 https://reactome.org/PathwayBrowser/#/R-RNO-176517 SULTs transfer (SO4)2- group to PREG IEA Rattus norvegicus 58343 R-RNO-176521 https://reactome.org/PathwayBrowser/#/R-RNO-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Rattus norvegicus 58343 R-RNO-176585 https://reactome.org/PathwayBrowser/#/R-RNO-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Rattus norvegicus 58343 R-RNO-176588 https://reactome.org/PathwayBrowser/#/R-RNO-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Rattus norvegicus 58343 R-RNO-176604 https://reactome.org/PathwayBrowser/#/R-RNO-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Rattus norvegicus 58343 R-RNO-176606 https://reactome.org/PathwayBrowser/#/R-RNO-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Rattus norvegicus 58343 R-RNO-176609 https://reactome.org/PathwayBrowser/#/R-RNO-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Rattus norvegicus 58343 R-RNO-176631 https://reactome.org/PathwayBrowser/#/R-RNO-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Rattus norvegicus 58343 R-RNO-176646 https://reactome.org/PathwayBrowser/#/R-RNO-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Rattus norvegicus 58343 R-RNO-176664 https://reactome.org/PathwayBrowser/#/R-RNO-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Rattus norvegicus 58343 R-RNO-176669 https://reactome.org/PathwayBrowser/#/R-RNO-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Rattus norvegicus 58343 R-RNO-1971483 https://reactome.org/PathwayBrowser/#/R-RNO-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Rattus norvegicus 58343 R-RNO-199202 https://reactome.org/PathwayBrowser/#/R-RNO-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Rattus norvegicus 58343 R-RNO-2018659 https://reactome.org/PathwayBrowser/#/R-RNO-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Rattus norvegicus 58343 R-RNO-2018682 https://reactome.org/PathwayBrowser/#/R-RNO-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Rattus norvegicus 58343 R-RNO-2022061 https://reactome.org/PathwayBrowser/#/R-RNO-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Rattus norvegicus 58343 R-RNO-2022063 https://reactome.org/PathwayBrowser/#/R-RNO-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Rattus norvegicus 58343 R-RNO-2022860 https://reactome.org/PathwayBrowser/#/R-RNO-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Rattus norvegicus 58343 R-RNO-2046175 https://reactome.org/PathwayBrowser/#/R-RNO-2046175 Further sulfation on galactose residues produces KSPG IEA Rattus norvegicus 58343 R-RNO-2046222 https://reactome.org/PathwayBrowser/#/R-RNO-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Rattus norvegicus 58343 R-RNO-2076383 https://reactome.org/PathwayBrowser/#/R-RNO-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Rattus norvegicus 58343 R-RNO-2076419 https://reactome.org/PathwayBrowser/#/R-RNO-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Rattus norvegicus 58343 R-RNO-2076508 https://reactome.org/PathwayBrowser/#/R-RNO-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Rattus norvegicus 58343 R-RNO-2076611 https://reactome.org/PathwayBrowser/#/R-RNO-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Rattus norvegicus 58343 R-RNO-6786012 https://reactome.org/PathwayBrowser/#/R-RNO-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Rattus norvegicus 58343 R-RNO-6786048 https://reactome.org/PathwayBrowser/#/R-RNO-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Rattus norvegicus 58343 R-RNO-8953499 https://reactome.org/PathwayBrowser/#/R-RNO-8953499 IMPAD1 hydrolyses PAP to AMP IEA Rattus norvegicus 58343 R-RNO-8954262 https://reactome.org/PathwayBrowser/#/R-RNO-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Rattus norvegicus 58343 R-RNO-9668023 https://reactome.org/PathwayBrowser/#/R-RNO-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII IEA Rattus norvegicus 58343 R-RNO-9753277 https://reactome.org/PathwayBrowser/#/R-RNO-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Rattus norvegicus 58343 R-RNO-9844587 https://reactome.org/PathwayBrowser/#/R-RNO-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Rattus norvegicus 58343 R-SCE-2408518 https://reactome.org/PathwayBrowser/#/R-SCE-2408518 PAPSe is reduced to SeO3(2-) by MET16 TAS Saccharomyces cerevisiae 58343 R-SSC-158468 https://reactome.org/PathwayBrowser/#/R-SSC-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Sus scrofa 58343 R-SSC-158849 https://reactome.org/PathwayBrowser/#/R-SSC-158849 Phenol can form a sulfate conjugate IEA Sus scrofa 58343 R-SSC-158860 https://reactome.org/PathwayBrowser/#/R-SSC-158860 SULT1A1 dimer sulfonates NHABP IEA Sus scrofa 58343 R-SSC-159358 https://reactome.org/PathwayBrowser/#/R-SSC-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Sus scrofa 58343 R-SSC-176474 https://reactome.org/PathwayBrowser/#/R-SSC-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Sus scrofa 58343 R-SSC-176494 https://reactome.org/PathwayBrowser/#/R-SSC-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Sus scrofa 58343 R-SSC-176517 https://reactome.org/PathwayBrowser/#/R-SSC-176517 SULTs transfer (SO4)2- group to PREG IEA Sus scrofa 58343 R-SSC-176521 https://reactome.org/PathwayBrowser/#/R-SSC-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Sus scrofa 58343 R-SSC-176585 https://reactome.org/PathwayBrowser/#/R-SSC-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Sus scrofa 58343 R-SSC-176588 https://reactome.org/PathwayBrowser/#/R-SSC-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Sus scrofa 58343 R-SSC-176604 https://reactome.org/PathwayBrowser/#/R-SSC-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Sus scrofa 58343 R-SSC-176606 https://reactome.org/PathwayBrowser/#/R-SSC-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Sus scrofa 58343 R-SSC-176609 https://reactome.org/PathwayBrowser/#/R-SSC-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Sus scrofa 58343 R-SSC-176631 https://reactome.org/PathwayBrowser/#/R-SSC-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Sus scrofa 58343 R-SSC-176646 https://reactome.org/PathwayBrowser/#/R-SSC-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Sus scrofa 58343 R-SSC-176664 https://reactome.org/PathwayBrowser/#/R-SSC-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Sus scrofa 58343 R-SSC-176669 https://reactome.org/PathwayBrowser/#/R-SSC-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Sus scrofa 58343 R-SSC-1971483 https://reactome.org/PathwayBrowser/#/R-SSC-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Sus scrofa 58343 R-SSC-199202 https://reactome.org/PathwayBrowser/#/R-SSC-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Sus scrofa 58343 R-SSC-2018659 https://reactome.org/PathwayBrowser/#/R-SSC-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Sus scrofa 58343 R-SSC-2018682 https://reactome.org/PathwayBrowser/#/R-SSC-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Sus scrofa 58343 R-SSC-2022061 https://reactome.org/PathwayBrowser/#/R-SSC-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Sus scrofa 58343 R-SSC-2022063 https://reactome.org/PathwayBrowser/#/R-SSC-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Sus scrofa 58343 R-SSC-2022860 https://reactome.org/PathwayBrowser/#/R-SSC-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Sus scrofa 58343 R-SSC-2046175 https://reactome.org/PathwayBrowser/#/R-SSC-2046175 Further sulfation on galactose residues produces KSPG IEA Sus scrofa 58343 R-SSC-2046222 https://reactome.org/PathwayBrowser/#/R-SSC-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Sus scrofa 58343 R-SSC-2076383 https://reactome.org/PathwayBrowser/#/R-SSC-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Sus scrofa 58343 R-SSC-2076419 https://reactome.org/PathwayBrowser/#/R-SSC-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Sus scrofa 58343 R-SSC-2076508 https://reactome.org/PathwayBrowser/#/R-SSC-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Sus scrofa 58343 R-SSC-2076611 https://reactome.org/PathwayBrowser/#/R-SSC-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Sus scrofa 58343 R-SSC-6786012 https://reactome.org/PathwayBrowser/#/R-SSC-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Sus scrofa 58343 R-SSC-6786034 https://reactome.org/PathwayBrowser/#/R-SSC-6786034 CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin IEA Sus scrofa 58343 R-SSC-6786048 https://reactome.org/PathwayBrowser/#/R-SSC-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Sus scrofa 58343 R-SSC-8953499 https://reactome.org/PathwayBrowser/#/R-SSC-8953499 IMPAD1 hydrolyses PAP to AMP IEA Sus scrofa 58343 R-SSC-8954262 https://reactome.org/PathwayBrowser/#/R-SSC-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Sus scrofa 58343 R-SSC-9753277 https://reactome.org/PathwayBrowser/#/R-SSC-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Sus scrofa 58343 R-SSC-9844587 https://reactome.org/PathwayBrowser/#/R-SSC-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Sus scrofa 58343 R-XTR-158468 https://reactome.org/PathwayBrowser/#/R-XTR-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Xenopus tropicalis 58343 R-XTR-158849 https://reactome.org/PathwayBrowser/#/R-XTR-158849 Phenol can form a sulfate conjugate IEA Xenopus tropicalis 58343 R-XTR-158860 https://reactome.org/PathwayBrowser/#/R-XTR-158860 SULT1A1 dimer sulfonates NHABP IEA Xenopus tropicalis 58343 R-XTR-159358 https://reactome.org/PathwayBrowser/#/R-XTR-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Xenopus tropicalis 58343 R-XTR-176474 https://reactome.org/PathwayBrowser/#/R-XTR-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Xenopus tropicalis 58343 R-XTR-176494 https://reactome.org/PathwayBrowser/#/R-XTR-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Xenopus tropicalis 58343 R-XTR-176517 https://reactome.org/PathwayBrowser/#/R-XTR-176517 SULTs transfer (SO4)2- group to PREG IEA Xenopus tropicalis 58343 R-XTR-176521 https://reactome.org/PathwayBrowser/#/R-XTR-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Xenopus tropicalis 58343 R-XTR-176585 https://reactome.org/PathwayBrowser/#/R-XTR-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Xenopus tropicalis 58343 R-XTR-176588 https://reactome.org/PathwayBrowser/#/R-XTR-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Xenopus tropicalis 58343 R-XTR-176604 https://reactome.org/PathwayBrowser/#/R-XTR-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Xenopus tropicalis 58343 R-XTR-176606 https://reactome.org/PathwayBrowser/#/R-XTR-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Xenopus tropicalis 58343 R-XTR-176609 https://reactome.org/PathwayBrowser/#/R-XTR-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Xenopus tropicalis 58343 R-XTR-176631 https://reactome.org/PathwayBrowser/#/R-XTR-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Xenopus tropicalis 58343 R-XTR-176646 https://reactome.org/PathwayBrowser/#/R-XTR-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Xenopus tropicalis 58343 R-XTR-176664 https://reactome.org/PathwayBrowser/#/R-XTR-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Xenopus tropicalis 58343 R-XTR-176669 https://reactome.org/PathwayBrowser/#/R-XTR-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Xenopus tropicalis 58343 R-XTR-1971483 https://reactome.org/PathwayBrowser/#/R-XTR-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Xenopus tropicalis 58343 R-XTR-199202 https://reactome.org/PathwayBrowser/#/R-XTR-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Xenopus tropicalis 58343 R-XTR-2018659 https://reactome.org/PathwayBrowser/#/R-XTR-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Xenopus tropicalis 58343 R-XTR-2018682 https://reactome.org/PathwayBrowser/#/R-XTR-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Xenopus tropicalis 58343 R-XTR-2022063 https://reactome.org/PathwayBrowser/#/R-XTR-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Xenopus tropicalis 58343 R-XTR-2022860 https://reactome.org/PathwayBrowser/#/R-XTR-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Xenopus tropicalis 58343 R-XTR-2046175 https://reactome.org/PathwayBrowser/#/R-XTR-2046175 Further sulfation on galactose residues produces KSPG IEA Xenopus tropicalis 58343 R-XTR-2046222 https://reactome.org/PathwayBrowser/#/R-XTR-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Xenopus tropicalis 58343 R-XTR-2076383 https://reactome.org/PathwayBrowser/#/R-XTR-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Xenopus tropicalis 58343 R-XTR-2076419 https://reactome.org/PathwayBrowser/#/R-XTR-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Xenopus tropicalis 58343 R-XTR-2076508 https://reactome.org/PathwayBrowser/#/R-XTR-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Xenopus tropicalis 58343 R-XTR-2076611 https://reactome.org/PathwayBrowser/#/R-XTR-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Xenopus tropicalis 58343 R-XTR-6786012 https://reactome.org/PathwayBrowser/#/R-XTR-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Xenopus tropicalis 58343 R-XTR-8953499 https://reactome.org/PathwayBrowser/#/R-XTR-8953499 IMPAD1 hydrolyses PAP to AMP IEA Xenopus tropicalis 58343 R-XTR-8954262 https://reactome.org/PathwayBrowser/#/R-XTR-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Xenopus tropicalis 58343 R-XTR-9753277 https://reactome.org/PathwayBrowser/#/R-XTR-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Xenopus tropicalis 58343 R-XTR-9844587 https://reactome.org/PathwayBrowser/#/R-XTR-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Xenopus tropicalis 58349 R-BTA-1222376 https://reactome.org/PathwayBrowser/#/R-BTA-1222376 NOX2 generates superoxide from oxygen IEA Bos taurus 58349 R-BTA-1475414 https://reactome.org/PathwayBrowser/#/R-BTA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Bos taurus 58349 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 58349 R-BTA-1497869 https://reactome.org/PathwayBrowser/#/R-BTA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Bos taurus 58349 R-BTA-156526 https://reactome.org/PathwayBrowser/#/R-BTA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Bos taurus 58349 R-BTA-1655453 https://reactome.org/PathwayBrowser/#/R-BTA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Bos taurus 58349 R-BTA-189384 https://reactome.org/PathwayBrowser/#/R-BTA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Bos taurus 58349 R-BTA-189398 https://reactome.org/PathwayBrowser/#/R-BTA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Bos taurus 58349 R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 58349 R-BTA-191352 https://reactome.org/PathwayBrowser/#/R-BTA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Bos taurus 58349 R-BTA-191402 https://reactome.org/PathwayBrowser/#/R-BTA-191402 Reduction of presqualene diphosphate to form squalene IEA Bos taurus 58349 R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 58349 R-BTA-191999 https://reactome.org/PathwayBrowser/#/R-BTA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Bos taurus 58349 R-BTA-192033 https://reactome.org/PathwayBrowser/#/R-BTA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Bos taurus 58349 R-BTA-192036 https://reactome.org/PathwayBrowser/#/R-BTA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Bos taurus 58349 R-BTA-192042 https://reactome.org/PathwayBrowser/#/R-BTA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 58349 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 58349 R-BTA-192054 https://reactome.org/PathwayBrowser/#/R-BTA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Bos taurus 58349 R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 58349 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 58349 R-BTA-192067 https://reactome.org/PathwayBrowser/#/R-BTA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Bos taurus 58349 R-BTA-192123 https://reactome.org/PathwayBrowser/#/R-BTA-192123 CYP27A1 27-hydroxylates CHOL IEA Bos taurus 58349 R-BTA-192160 https://reactome.org/PathwayBrowser/#/R-BTA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Bos taurus 58349 R-BTA-192178 https://reactome.org/PathwayBrowser/#/R-BTA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Bos taurus 58349 R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 58349 R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 58349 R-BTA-193064 https://reactome.org/PathwayBrowser/#/R-BTA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Bos taurus 58349 R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 58349 R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 58349 R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 58349 R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 58349 R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 58349 R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 58349 R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 58349 R-BTA-193393 https://reactome.org/PathwayBrowser/#/R-BTA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Bos taurus 58349 R-BTA-193460 https://reactome.org/PathwayBrowser/#/R-BTA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Bos taurus 58349 R-BTA-193497 https://reactome.org/PathwayBrowser/#/R-BTA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Bos taurus 58349 R-BTA-193713 https://reactome.org/PathwayBrowser/#/R-BTA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Bos taurus 58349 R-BTA-193719 https://reactome.org/PathwayBrowser/#/R-BTA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 58349 R-BTA-193737 https://reactome.org/PathwayBrowser/#/R-BTA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Bos taurus 58349 R-BTA-193746 https://reactome.org/PathwayBrowser/#/R-BTA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Bos taurus 58349 R-BTA-193755 https://reactome.org/PathwayBrowser/#/R-BTA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Bos taurus 58349 R-BTA-193758 https://reactome.org/PathwayBrowser/#/R-BTA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Bos taurus 58349 R-BTA-193780 https://reactome.org/PathwayBrowser/#/R-BTA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Bos taurus 58349 R-BTA-193781 https://reactome.org/PathwayBrowser/#/R-BTA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Bos taurus 58349 R-BTA-193787 https://reactome.org/PathwayBrowser/#/R-BTA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Bos taurus 58349 R-BTA-193792 https://reactome.org/PathwayBrowser/#/R-BTA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Bos taurus 58349 R-BTA-193800 https://reactome.org/PathwayBrowser/#/R-BTA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Bos taurus 58349 R-BTA-193821 https://reactome.org/PathwayBrowser/#/R-BTA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Bos taurus 58349 R-BTA-193824 https://reactome.org/PathwayBrowser/#/R-BTA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Bos taurus 58349 R-BTA-193841 https://reactome.org/PathwayBrowser/#/R-BTA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Bos taurus 58349 R-BTA-193964 https://reactome.org/PathwayBrowser/#/R-BTA-193964 CYP21A2 21-hydroxylates PROG IEA Bos taurus 58349 R-BTA-193965 https://reactome.org/PathwayBrowser/#/R-BTA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Bos taurus 58349 R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 58349 R-BTA-193995 https://reactome.org/PathwayBrowser/#/R-BTA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Bos taurus 58349 R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 58349 R-BTA-194017 https://reactome.org/PathwayBrowser/#/R-BTA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Bos taurus 58349 R-BTA-194023 https://reactome.org/PathwayBrowser/#/R-BTA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Bos taurus 58349 R-BTA-194632 https://reactome.org/PathwayBrowser/#/R-BTA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Bos taurus 58349 R-BTA-194641 https://reactome.org/PathwayBrowser/#/R-BTA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 58349 R-BTA-194669 https://reactome.org/PathwayBrowser/#/R-BTA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 58349 R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 58349 R-BTA-194689 https://reactome.org/PathwayBrowser/#/R-BTA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Bos taurus 58349 R-BTA-194698 https://reactome.org/PathwayBrowser/#/R-BTA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Bos taurus 58349 R-BTA-195664 https://reactome.org/PathwayBrowser/#/R-BTA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Bos taurus 58349 R-BTA-196060 https://reactome.org/PathwayBrowser/#/R-BTA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Bos taurus 58349 R-BTA-196402 https://reactome.org/PathwayBrowser/#/R-BTA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Bos taurus 58349 R-BTA-196417 https://reactome.org/PathwayBrowser/#/R-BTA-196417 Reduction of desmosterol to cholesterol IEA Bos taurus 58349 R-BTA-197198 https://reactome.org/PathwayBrowser/#/R-BTA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Bos taurus 58349 R-BTA-197963 https://reactome.org/PathwayBrowser/#/R-BTA-197963 DHFR2 reduces FOLA to DHF IEA Bos taurus 58349 R-BTA-197972 https://reactome.org/PathwayBrowser/#/R-BTA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Bos taurus 58349 R-BTA-200644 https://reactome.org/PathwayBrowser/#/R-BTA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Bos taurus 58349 R-BTA-200676 https://reactome.org/PathwayBrowser/#/R-BTA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Bos taurus 58349 R-BTA-200718 https://reactome.org/PathwayBrowser/#/R-BTA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Bos taurus 58349 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 58349 R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 58349 R-BTA-209772 https://reactome.org/PathwayBrowser/#/R-BTA-209772 Thyroxine is deiodinated to triiodothyronine IEA Bos taurus 58349 R-BTA-209845 https://reactome.org/PathwayBrowser/#/R-BTA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Bos taurus 58349 R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 58349 R-BTA-211873 https://reactome.org/PathwayBrowser/#/R-BTA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Bos taurus 58349 R-BTA-211923 https://reactome.org/PathwayBrowser/#/R-BTA-211923 CYP26C1 4-hydroxylates 9cRA IEA Bos taurus 58349 R-BTA-211950 https://reactome.org/PathwayBrowser/#/R-BTA-211950 CYP24A1 24-hydroxylates CTL IEA Bos taurus 58349 R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 58349 R-BTA-2161549 https://reactome.org/PathwayBrowser/#/R-BTA-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Bos taurus 58349 R-BTA-2161614 https://reactome.org/PathwayBrowser/#/R-BTA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Bos taurus 58349 R-BTA-2161651 https://reactome.org/PathwayBrowser/#/R-BTA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Bos taurus 58349 R-BTA-2161745 https://reactome.org/PathwayBrowser/#/R-BTA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Bos taurus 58349 R-BTA-2161792 https://reactome.org/PathwayBrowser/#/R-BTA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Bos taurus 58349 R-BTA-2161890 https://reactome.org/PathwayBrowser/#/R-BTA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Bos taurus 58349 R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Bos taurus 58349 R-BTA-2161951 https://reactome.org/PathwayBrowser/#/R-BTA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Bos taurus 58349 R-BTA-2395517 https://reactome.org/PathwayBrowser/#/R-BTA-2395517 NADPH transfers electrons to FDXR IEA Bos taurus 58349 R-BTA-2408527 https://reactome.org/PathwayBrowser/#/R-BTA-2408527 SeO3(2-) is reduced to H2Se by TXNRD1 TAS Bos taurus 58349 R-BTA-2464776 https://reactome.org/PathwayBrowser/#/R-BTA-2464776 Rdh8 reduces atRAL to atROL TAS Bos taurus 58349 R-BTA-2464822 https://reactome.org/PathwayBrowser/#/R-BTA-2464822 RDH12 reduces atRAL to atROL IEA Bos taurus 58349 R-BTA-2465940 https://reactome.org/PathwayBrowser/#/R-BTA-2465940 atRAL is reduced to atROL IEA Bos taurus 58349 R-BTA-2855252 https://reactome.org/PathwayBrowser/#/R-BTA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Bos taurus 58349 R-BTA-3149518 https://reactome.org/PathwayBrowser/#/R-BTA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Bos taurus 58349 R-BTA-3149519 https://reactome.org/PathwayBrowser/#/R-BTA-3149519 MMACHC decyanates CNCbl IEA Bos taurus 58349 R-BTA-3323050 https://reactome.org/PathwayBrowser/#/R-BTA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Bos taurus 58349 R-BTA-3323079 https://reactome.org/PathwayBrowser/#/R-BTA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 58349 R-BTA-350869 https://reactome.org/PathwayBrowser/#/R-BTA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Bos taurus 58349 R-BTA-389540 https://reactome.org/PathwayBrowser/#/R-BTA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 58349 R-BTA-390425 https://reactome.org/PathwayBrowser/#/R-BTA-390425 FAR1 reduces PalmCoA to HXOL IEA Bos taurus 58349 R-BTA-390438 https://reactome.org/PathwayBrowser/#/R-BTA-390438 FAR2 reduces PalmCoA to HXOL IEA Bos taurus 58349 R-BTA-418436 https://reactome.org/PathwayBrowser/#/R-BTA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Bos taurus 58349 R-BTA-428123 https://reactome.org/PathwayBrowser/#/R-BTA-428123 KDSR reduces 3-ketosphingoid IEA Bos taurus 58349 R-BTA-4419979 https://reactome.org/PathwayBrowser/#/R-BTA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Bos taurus 58349 R-BTA-450971 https://reactome.org/PathwayBrowser/#/R-BTA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Bos taurus 58349 R-BTA-450984 https://reactome.org/PathwayBrowser/#/R-BTA-450984 IDH2 dimer decarboxylates isocitrate IEA Bos taurus 58349 R-BTA-469659 https://reactome.org/PathwayBrowser/#/R-BTA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Bos taurus 58349 R-BTA-508040 https://reactome.org/PathwayBrowser/#/R-BTA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Bos taurus 58349 R-BTA-514604 https://reactome.org/PathwayBrowser/#/R-BTA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Bos taurus 58349 R-BTA-5218841 https://reactome.org/PathwayBrowser/#/R-BTA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Bos taurus 58349 R-BTA-5263614 https://reactome.org/PathwayBrowser/#/R-BTA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Bos taurus 58349 R-BTA-5263616 https://reactome.org/PathwayBrowser/#/R-BTA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Bos taurus 58349 R-BTA-5340226 https://reactome.org/PathwayBrowser/#/R-BTA-5340226 CYGB dioxygenates NO IEA Bos taurus 58349 R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 58349 R-BTA-5419165 https://reactome.org/PathwayBrowser/#/R-BTA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Bos taurus 58349 R-BTA-5423637 https://reactome.org/PathwayBrowser/#/R-BTA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Bos taurus 58349 R-BTA-5423647 https://reactome.org/PathwayBrowser/#/R-BTA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Bos taurus 58349 R-BTA-5423664 https://reactome.org/PathwayBrowser/#/R-BTA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Bos taurus 58349 R-BTA-5423672 https://reactome.org/PathwayBrowser/#/R-BTA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Bos taurus 58349 R-BTA-5423678 https://reactome.org/PathwayBrowser/#/R-BTA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Bos taurus 58349 R-BTA-548818 https://reactome.org/PathwayBrowser/#/R-BTA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Bos taurus 58349 R-BTA-548831 https://reactome.org/PathwayBrowser/#/R-BTA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Bos taurus 58349 R-BTA-5602295 https://reactome.org/PathwayBrowser/#/R-BTA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Bos taurus 58349 R-BTA-5615668 https://reactome.org/PathwayBrowser/#/R-BTA-5615668 AKR1C3 reduces atRAL to atROL IEA Bos taurus 58349 R-BTA-5652172 https://reactome.org/PathwayBrowser/#/R-BTA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Bos taurus 58349 R-BTA-5661240 https://reactome.org/PathwayBrowser/#/R-BTA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Bos taurus 58349 R-BTA-5661256 https://reactome.org/PathwayBrowser/#/R-BTA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Bos taurus 58349 R-BTA-5668629 https://reactome.org/PathwayBrowser/#/R-BTA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Bos taurus 58349 R-BTA-5668718 https://reactome.org/PathwayBrowser/#/R-BTA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 58349 R-BTA-5668731 https://reactome.org/PathwayBrowser/#/R-BTA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 58349 R-BTA-5692232 https://reactome.org/PathwayBrowser/#/R-BTA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Bos taurus 58349 R-BTA-5692283 https://reactome.org/PathwayBrowser/#/R-BTA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Bos taurus 58349 R-BTA-5693390 https://reactome.org/PathwayBrowser/#/R-BTA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Bos taurus 58349 R-BTA-5696822 https://reactome.org/PathwayBrowser/#/R-BTA-5696822 AKR1B15 reduces EST17b to E1 IEA Bos taurus 58349 R-BTA-6783955 https://reactome.org/PathwayBrowser/#/R-BTA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 58349 R-BTA-6786239 https://reactome.org/PathwayBrowser/#/R-BTA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Bos taurus 58349 R-BTA-6787642 https://reactome.org/PathwayBrowser/#/R-BTA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Bos taurus 58349 R-BTA-6789092 https://reactome.org/PathwayBrowser/#/R-BTA-6789092 NOX2 generates superoxide anion from oxygen IEA Bos taurus 58349 R-BTA-6799722 https://reactome.org/PathwayBrowser/#/R-BTA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Bos taurus 58349 R-BTA-6807053 https://reactome.org/PathwayBrowser/#/R-BTA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Bos taurus 58349 R-BTA-6807055 https://reactome.org/PathwayBrowser/#/R-BTA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Bos taurus 58349 R-BTA-6807064 https://reactome.org/PathwayBrowser/#/R-BTA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Bos taurus 58349 R-BTA-6807557 https://reactome.org/PathwayBrowser/#/R-BTA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Bos taurus 58349 R-BTA-6808487 https://reactome.org/PathwayBrowser/#/R-BTA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 58349 R-BTA-6808496 https://reactome.org/PathwayBrowser/#/R-BTA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 58349 R-BTA-6810594 https://reactome.org/PathwayBrowser/#/R-BTA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 58349 R-BTA-70377 https://reactome.org/PathwayBrowser/#/R-BTA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Bos taurus 58349 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Bos taurus 58349 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Bos taurus 58349 R-BTA-70938 https://reactome.org/PathwayBrowser/#/R-BTA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Bos taurus 58349 R-BTA-71200 https://reactome.org/PathwayBrowser/#/R-BTA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Bos taurus 58349 R-BTA-71299 https://reactome.org/PathwayBrowser/#/R-BTA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Bos taurus 58349 R-BTA-71682 https://reactome.org/PathwayBrowser/#/R-BTA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 58349 R-BTA-73585 https://reactome.org/PathwayBrowser/#/R-BTA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Bos taurus 58349 R-BTA-73616 https://reactome.org/PathwayBrowser/#/R-BTA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Bos taurus 58349 R-BTA-73646 https://reactome.org/PathwayBrowser/#/R-BTA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Bos taurus 58349 R-BTA-74872 https://reactome.org/PathwayBrowser/#/R-BTA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Bos taurus 58349 R-BTA-75872 https://reactome.org/PathwayBrowser/#/R-BTA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Bos taurus 58349 R-BTA-75883 https://reactome.org/PathwayBrowser/#/R-BTA-75883 DHRS7B reduces GO3P to HXDG3P IEA Bos taurus 58349 R-BTA-804969 https://reactome.org/PathwayBrowser/#/R-BTA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Bos taurus 58349 R-BTA-8862137 https://reactome.org/PathwayBrowser/#/R-BTA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 58349 R-BTA-8862152 https://reactome.org/PathwayBrowser/#/R-BTA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Bos taurus 58349 R-BTA-8937419 https://reactome.org/PathwayBrowser/#/R-BTA-8937419 CBR3 reduces DOX to DOXOL IEA Bos taurus 58349 R-BTA-8952873 https://reactome.org/PathwayBrowser/#/R-BTA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Bos taurus 58349 R-BTA-8955030 https://reactome.org/PathwayBrowser/#/R-BTA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Bos taurus 58349 R-BTA-9012036 https://reactome.org/PathwayBrowser/#/R-BTA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Bos taurus 58349 R-BTA-9012349 https://reactome.org/PathwayBrowser/#/R-BTA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Bos taurus 58349 R-BTA-9020255 https://reactome.org/PathwayBrowser/#/R-BTA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Bos taurus 58349 R-BTA-9020256 https://reactome.org/PathwayBrowser/#/R-BTA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Bos taurus 58349 R-BTA-9020262 https://reactome.org/PathwayBrowser/#/R-BTA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Bos taurus 58349 R-BTA-9020277 https://reactome.org/PathwayBrowser/#/R-BTA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Bos taurus 58349 R-BTA-9020278 https://reactome.org/PathwayBrowser/#/R-BTA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Bos taurus 58349 R-BTA-9024881 https://reactome.org/PathwayBrowser/#/R-BTA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Bos taurus 58349 R-BTA-9024983 https://reactome.org/PathwayBrowser/#/R-BTA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Bos taurus 58349 R-BTA-9025995 https://reactome.org/PathwayBrowser/#/R-BTA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Bos taurus 58349 R-BTA-9025999 https://reactome.org/PathwayBrowser/#/R-BTA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Bos taurus 58349 R-BTA-9026007 https://reactome.org/PathwayBrowser/#/R-BTA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Bos taurus 58349 R-BTA-9027043 https://reactome.org/PathwayBrowser/#/R-BTA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Bos taurus 58349 R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 58349 R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 58349 R-BTA-9037761 https://reactome.org/PathwayBrowser/#/R-BTA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Bos taurus 58349 R-BTA-917811 https://reactome.org/PathwayBrowser/#/R-BTA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Bos taurus 58349 R-BTA-9705713 https://reactome.org/PathwayBrowser/#/R-BTA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Bos taurus 58349 R-BTA-9705714 https://reactome.org/PathwayBrowser/#/R-BTA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Bos taurus 58349 R-BTA-9709098 https://reactome.org/PathwayBrowser/#/R-BTA-9709098 DHFR dimer reduces FOLA to DHF IEA Bos taurus 58349 R-BTA-9753285 https://reactome.org/PathwayBrowser/#/R-BTA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Bos taurus 58349 R-BTA-9755937 https://reactome.org/PathwayBrowser/#/R-BTA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Bos taurus 58349 R-BTA-9756138 https://reactome.org/PathwayBrowser/#/R-BTA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Bos taurus 58349 R-BTA-9756162 https://reactome.org/PathwayBrowser/#/R-BTA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Bos taurus 58349 R-BTA-9756169 https://reactome.org/PathwayBrowser/#/R-BTA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Bos taurus 58349 R-BTA-9756180 https://reactome.org/PathwayBrowser/#/R-BTA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Bos taurus 58349 R-BTA-975629 https://reactome.org/PathwayBrowser/#/R-BTA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Bos taurus 58349 R-BTA-9758682 https://reactome.org/PathwayBrowser/#/R-BTA-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Bos taurus 58349 R-BTA-9759259 https://reactome.org/PathwayBrowser/#/R-BTA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Bos taurus 58349 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 58349 R-CEL-156526 https://reactome.org/PathwayBrowser/#/R-CEL-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Caenorhabditis elegans 58349 R-CEL-1655453 https://reactome.org/PathwayBrowser/#/R-CEL-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Caenorhabditis elegans 58349 R-CEL-191352 https://reactome.org/PathwayBrowser/#/R-CEL-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Caenorhabditis elegans 58349 R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 58349 R-CEL-192033 https://reactome.org/PathwayBrowser/#/R-CEL-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Caenorhabditis elegans 58349 R-CEL-192036 https://reactome.org/PathwayBrowser/#/R-CEL-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Caenorhabditis elegans 58349 R-CEL-192067 https://reactome.org/PathwayBrowser/#/R-CEL-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Caenorhabditis elegans 58349 R-CEL-192160 https://reactome.org/PathwayBrowser/#/R-CEL-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Caenorhabditis elegans 58349 R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 58349 R-CEL-193064 https://reactome.org/PathwayBrowser/#/R-CEL-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Caenorhabditis elegans 58349 R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 58349 R-CEL-193746 https://reactome.org/PathwayBrowser/#/R-CEL-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Caenorhabditis elegans 58349 R-CEL-193755 https://reactome.org/PathwayBrowser/#/R-CEL-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Caenorhabditis elegans 58349 R-CEL-193758 https://reactome.org/PathwayBrowser/#/R-CEL-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Caenorhabditis elegans 58349 R-CEL-193781 https://reactome.org/PathwayBrowser/#/R-CEL-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Caenorhabditis elegans 58349 R-CEL-193800 https://reactome.org/PathwayBrowser/#/R-CEL-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Caenorhabditis elegans 58349 R-CEL-193821 https://reactome.org/PathwayBrowser/#/R-CEL-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Caenorhabditis elegans 58349 R-CEL-193824 https://reactome.org/PathwayBrowser/#/R-CEL-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Caenorhabditis elegans 58349 R-CEL-193841 https://reactome.org/PathwayBrowser/#/R-CEL-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Caenorhabditis elegans 58349 R-CEL-196060 https://reactome.org/PathwayBrowser/#/R-CEL-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Caenorhabditis elegans 58349 R-CEL-196402 https://reactome.org/PathwayBrowser/#/R-CEL-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Caenorhabditis elegans 58349 R-CEL-196417 https://reactome.org/PathwayBrowser/#/R-CEL-196417 Reduction of desmosterol to cholesterol IEA Caenorhabditis elegans 58349 R-CEL-197963 https://reactome.org/PathwayBrowser/#/R-CEL-197963 DHFR2 reduces FOLA to DHF IEA Caenorhabditis elegans 58349 R-CEL-197972 https://reactome.org/PathwayBrowser/#/R-CEL-197972 DHF is reduced to tetrahydrofolate (THF) IEA Caenorhabditis elegans 58349 R-CEL-200644 https://reactome.org/PathwayBrowser/#/R-CEL-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Caenorhabditis elegans 58349 R-CEL-200676 https://reactome.org/PathwayBrowser/#/R-CEL-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Caenorhabditis elegans 58349 R-CEL-200718 https://reactome.org/PathwayBrowser/#/R-CEL-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Caenorhabditis elegans 58349 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 58349 R-CEL-209845 https://reactome.org/PathwayBrowser/#/R-CEL-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Caenorhabditis elegans 58349 R-CEL-2161549 https://reactome.org/PathwayBrowser/#/R-CEL-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Caenorhabditis elegans 58349 R-CEL-2161614 https://reactome.org/PathwayBrowser/#/R-CEL-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Caenorhabditis elegans 58349 R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans 58349 R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Caenorhabditis elegans 58349 R-CEL-2395517 https://reactome.org/PathwayBrowser/#/R-CEL-2395517 NADPH transfers electrons to FDXR IEA Caenorhabditis elegans 58349 R-CEL-2465940 https://reactome.org/PathwayBrowser/#/R-CEL-2465940 atRAL is reduced to atROL IEA Caenorhabditis elegans 58349 R-CEL-2855252 https://reactome.org/PathwayBrowser/#/R-CEL-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Caenorhabditis elegans 58349 R-CEL-3149518 https://reactome.org/PathwayBrowser/#/R-CEL-3149518 MTRR reduces cob(II)alamin to meCbl IEA Caenorhabditis elegans 58349 R-CEL-3149519 https://reactome.org/PathwayBrowser/#/R-CEL-3149519 MMACHC decyanates CNCbl IEA Caenorhabditis elegans 58349 R-CEL-3323050 https://reactome.org/PathwayBrowser/#/R-CEL-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Caenorhabditis elegans 58349 R-CEL-3323079 https://reactome.org/PathwayBrowser/#/R-CEL-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 58349 R-CEL-389540 https://reactome.org/PathwayBrowser/#/R-CEL-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 58349 R-CEL-390425 https://reactome.org/PathwayBrowser/#/R-CEL-390425 FAR1 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 58349 R-CEL-390438 https://reactome.org/PathwayBrowser/#/R-CEL-390438 FAR2 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 58349 R-CEL-428123 https://reactome.org/PathwayBrowser/#/R-CEL-428123 KDSR reduces 3-ketosphingoid IEA Caenorhabditis elegans 58349 R-CEL-4419979 https://reactome.org/PathwayBrowser/#/R-CEL-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Caenorhabditis elegans 58349 R-CEL-450971 https://reactome.org/PathwayBrowser/#/R-CEL-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Caenorhabditis elegans 58349 R-CEL-450984 https://reactome.org/PathwayBrowser/#/R-CEL-450984 IDH2 dimer decarboxylates isocitrate IEA Caenorhabditis elegans 58349 R-CEL-469659 https://reactome.org/PathwayBrowser/#/R-CEL-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 58349 R-CEL-508040 https://reactome.org/PathwayBrowser/#/R-CEL-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Caenorhabditis elegans 58349 R-CEL-514604 https://reactome.org/PathwayBrowser/#/R-CEL-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Caenorhabditis elegans 58349 R-CEL-5263614 https://reactome.org/PathwayBrowser/#/R-CEL-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Caenorhabditis elegans 58349 R-CEL-5263616 https://reactome.org/PathwayBrowser/#/R-CEL-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Caenorhabditis elegans 58349 R-CEL-5340226 https://reactome.org/PathwayBrowser/#/R-CEL-5340226 CYGB dioxygenates NO IEA Caenorhabditis elegans 58349 R-CEL-5419165 https://reactome.org/PathwayBrowser/#/R-CEL-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Caenorhabditis elegans 58349 R-CEL-5423647 https://reactome.org/PathwayBrowser/#/R-CEL-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Caenorhabditis elegans 58349 R-CEL-548818 https://reactome.org/PathwayBrowser/#/R-CEL-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Caenorhabditis elegans 58349 R-CEL-548831 https://reactome.org/PathwayBrowser/#/R-CEL-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Caenorhabditis elegans 58349 R-CEL-5615668 https://reactome.org/PathwayBrowser/#/R-CEL-5615668 AKR1C3 reduces atRAL to atROL IEA Caenorhabditis elegans 58349 R-CEL-5652172 https://reactome.org/PathwayBrowser/#/R-CEL-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Caenorhabditis elegans 58349 R-CEL-5661240 https://reactome.org/PathwayBrowser/#/R-CEL-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Caenorhabditis elegans 58349 R-CEL-5661256 https://reactome.org/PathwayBrowser/#/R-CEL-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Caenorhabditis elegans 58349 R-CEL-5692232 https://reactome.org/PathwayBrowser/#/R-CEL-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Caenorhabditis elegans 58349 R-CEL-5692283 https://reactome.org/PathwayBrowser/#/R-CEL-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Caenorhabditis elegans 58349 R-CEL-5696822 https://reactome.org/PathwayBrowser/#/R-CEL-5696822 AKR1B15 reduces EST17b to E1 IEA Caenorhabditis elegans 58349 R-CEL-6786239 https://reactome.org/PathwayBrowser/#/R-CEL-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Caenorhabditis elegans 58349 R-CEL-6787642 https://reactome.org/PathwayBrowser/#/R-CEL-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Caenorhabditis elegans 58349 R-CEL-6807055 https://reactome.org/PathwayBrowser/#/R-CEL-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Caenorhabditis elegans 58349 R-CEL-6807064 https://reactome.org/PathwayBrowser/#/R-CEL-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Caenorhabditis elegans 58349 R-CEL-6808487 https://reactome.org/PathwayBrowser/#/R-CEL-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 58349 R-CEL-6808496 https://reactome.org/PathwayBrowser/#/R-CEL-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 58349 R-CEL-70377 https://reactome.org/PathwayBrowser/#/R-CEL-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Caenorhabditis elegans 58349 R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Caenorhabditis elegans 58349 R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Caenorhabditis elegans 58349 R-CEL-70938 https://reactome.org/PathwayBrowser/#/R-CEL-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Caenorhabditis elegans 58349 R-CEL-71200 https://reactome.org/PathwayBrowser/#/R-CEL-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Caenorhabditis elegans 58349 R-CEL-71299 https://reactome.org/PathwayBrowser/#/R-CEL-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 58349 R-CEL-71682 https://reactome.org/PathwayBrowser/#/R-CEL-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 58349 R-CEL-73585 https://reactome.org/PathwayBrowser/#/R-CEL-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Caenorhabditis elegans 58349 R-CEL-73616 https://reactome.org/PathwayBrowser/#/R-CEL-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Caenorhabditis elegans 58349 R-CEL-73646 https://reactome.org/PathwayBrowser/#/R-CEL-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Caenorhabditis elegans 58349 R-CEL-75872 https://reactome.org/PathwayBrowser/#/R-CEL-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Caenorhabditis elegans 58349 R-CEL-75883 https://reactome.org/PathwayBrowser/#/R-CEL-75883 DHRS7B reduces GO3P to HXDG3P IEA Caenorhabditis elegans 58349 R-CEL-8865107 https://reactome.org/PathwayBrowser/#/R-CEL-8865107 MICAL1 produces NADP+, H2O2 IEA Caenorhabditis elegans 58349 R-CEL-8952873 https://reactome.org/PathwayBrowser/#/R-CEL-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Caenorhabditis elegans 58349 R-CEL-8955030 https://reactome.org/PathwayBrowser/#/R-CEL-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Caenorhabditis elegans 58349 R-CEL-9012036 https://reactome.org/PathwayBrowser/#/R-CEL-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 58349 R-CEL-9012349 https://reactome.org/PathwayBrowser/#/R-CEL-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 58349 R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans 58349 R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 58349 R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 58349 R-CEL-9705713 https://reactome.org/PathwayBrowser/#/R-CEL-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 58349 R-CEL-9705714 https://reactome.org/PathwayBrowser/#/R-CEL-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 58349 R-CEL-9709098 https://reactome.org/PathwayBrowser/#/R-CEL-9709098 DHFR dimer reduces FOLA to DHF IEA Caenorhabditis elegans 58349 R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans 58349 R-CEL-9755937 https://reactome.org/PathwayBrowser/#/R-CEL-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Caenorhabditis elegans 58349 R-CEL-9758682 https://reactome.org/PathwayBrowser/#/R-CEL-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Caenorhabditis elegans 58349 R-CFA-1222376 https://reactome.org/PathwayBrowser/#/R-CFA-1222376 NOX2 generates superoxide from oxygen IEA Canis familiaris 58349 R-CFA-1475414 https://reactome.org/PathwayBrowser/#/R-CFA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Canis familiaris 58349 R-CFA-1497869 https://reactome.org/PathwayBrowser/#/R-CFA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Canis familiaris 58349 R-CFA-156526 https://reactome.org/PathwayBrowser/#/R-CFA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Canis familiaris 58349 R-CFA-1655453 https://reactome.org/PathwayBrowser/#/R-CFA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Canis familiaris 58349 R-CFA-189384 https://reactome.org/PathwayBrowser/#/R-CFA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Canis familiaris 58349 R-CFA-189398 https://reactome.org/PathwayBrowser/#/R-CFA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Canis familiaris 58349 R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 58349 R-CFA-191352 https://reactome.org/PathwayBrowser/#/R-CFA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Canis familiaris 58349 R-CFA-191402 https://reactome.org/PathwayBrowser/#/R-CFA-191402 Reduction of presqualene diphosphate to form squalene IEA Canis familiaris 58349 R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 58349 R-CFA-191999 https://reactome.org/PathwayBrowser/#/R-CFA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Canis familiaris 58349 R-CFA-192033 https://reactome.org/PathwayBrowser/#/R-CFA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Canis familiaris 58349 R-CFA-192042 https://reactome.org/PathwayBrowser/#/R-CFA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 58349 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 58349 R-CFA-192054 https://reactome.org/PathwayBrowser/#/R-CFA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Canis familiaris 58349 R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 58349 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 58349 R-CFA-192067 https://reactome.org/PathwayBrowser/#/R-CFA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Canis familiaris 58349 R-CFA-192123 https://reactome.org/PathwayBrowser/#/R-CFA-192123 CYP27A1 27-hydroxylates CHOL IEA Canis familiaris 58349 R-CFA-192157 https://reactome.org/PathwayBrowser/#/R-CFA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Canis familiaris 58349 R-CFA-192178 https://reactome.org/PathwayBrowser/#/R-CFA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Canis familiaris 58349 R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 58349 R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 58349 R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 58349 R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 58349 R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 58349 R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 58349 R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 58349 R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 58349 R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 58349 R-CFA-193393 https://reactome.org/PathwayBrowser/#/R-CFA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Canis familiaris 58349 R-CFA-193460 https://reactome.org/PathwayBrowser/#/R-CFA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Canis familiaris 58349 R-CFA-193497 https://reactome.org/PathwayBrowser/#/R-CFA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Canis familiaris 58349 R-CFA-193709 https://reactome.org/PathwayBrowser/#/R-CFA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Canis familiaris 58349 R-CFA-193713 https://reactome.org/PathwayBrowser/#/R-CFA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Canis familiaris 58349 R-CFA-193719 https://reactome.org/PathwayBrowser/#/R-CFA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 58349 R-CFA-193737 https://reactome.org/PathwayBrowser/#/R-CFA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Canis familiaris 58349 R-CFA-193746 https://reactome.org/PathwayBrowser/#/R-CFA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Canis familiaris 58349 R-CFA-193755 https://reactome.org/PathwayBrowser/#/R-CFA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Canis familiaris 58349 R-CFA-193780 https://reactome.org/PathwayBrowser/#/R-CFA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Canis familiaris 58349 R-CFA-193787 https://reactome.org/PathwayBrowser/#/R-CFA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Canis familiaris 58349 R-CFA-193792 https://reactome.org/PathwayBrowser/#/R-CFA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Canis familiaris 58349 R-CFA-193821 https://reactome.org/PathwayBrowser/#/R-CFA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Canis familiaris 58349 R-CFA-193824 https://reactome.org/PathwayBrowser/#/R-CFA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Canis familiaris 58349 R-CFA-193845 https://reactome.org/PathwayBrowser/#/R-CFA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Canis familiaris 58349 R-CFA-193964 https://reactome.org/PathwayBrowser/#/R-CFA-193964 CYP21A2 21-hydroxylates PROG IEA Canis familiaris 58349 R-CFA-193965 https://reactome.org/PathwayBrowser/#/R-CFA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Canis familiaris 58349 R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 58349 R-CFA-193995 https://reactome.org/PathwayBrowser/#/R-CFA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Canis familiaris 58349 R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 58349 R-CFA-194017 https://reactome.org/PathwayBrowser/#/R-CFA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Canis familiaris 58349 R-CFA-194023 https://reactome.org/PathwayBrowser/#/R-CFA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Canis familiaris 58349 R-CFA-194632 https://reactome.org/PathwayBrowser/#/R-CFA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Canis familiaris 58349 R-CFA-194641 https://reactome.org/PathwayBrowser/#/R-CFA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 58349 R-CFA-194669 https://reactome.org/PathwayBrowser/#/R-CFA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 58349 R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 58349 R-CFA-194689 https://reactome.org/PathwayBrowser/#/R-CFA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 58349 R-CFA-194698 https://reactome.org/PathwayBrowser/#/R-CFA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Canis familiaris 58349 R-CFA-195664 https://reactome.org/PathwayBrowser/#/R-CFA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Canis familiaris 58349 R-CFA-196060 https://reactome.org/PathwayBrowser/#/R-CFA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Canis familiaris 58349 R-CFA-196402 https://reactome.org/PathwayBrowser/#/R-CFA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Canis familiaris 58349 R-CFA-196417 https://reactome.org/PathwayBrowser/#/R-CFA-196417 Reduction of desmosterol to cholesterol IEA Canis familiaris 58349 R-CFA-197198 https://reactome.org/PathwayBrowser/#/R-CFA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Canis familiaris 58349 R-CFA-197963 https://reactome.org/PathwayBrowser/#/R-CFA-197963 DHFR2 reduces FOLA to DHF IEA Canis familiaris 58349 R-CFA-197972 https://reactome.org/PathwayBrowser/#/R-CFA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Canis familiaris 58349 R-CFA-200644 https://reactome.org/PathwayBrowser/#/R-CFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Canis familiaris 58349 R-CFA-200676 https://reactome.org/PathwayBrowser/#/R-CFA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Canis familiaris 58349 R-CFA-200718 https://reactome.org/PathwayBrowser/#/R-CFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Canis familiaris 58349 R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 58349 R-CFA-209772 https://reactome.org/PathwayBrowser/#/R-CFA-209772 Thyroxine is deiodinated to triiodothyronine IEA Canis familiaris 58349 R-CFA-209845 https://reactome.org/PathwayBrowser/#/R-CFA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Canis familiaris 58349 R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 58349 R-CFA-211873 https://reactome.org/PathwayBrowser/#/R-CFA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Canis familiaris 58349 R-CFA-211923 https://reactome.org/PathwayBrowser/#/R-CFA-211923 CYP26C1 4-hydroxylates 9cRA IEA Canis familiaris 58349 R-CFA-211950 https://reactome.org/PathwayBrowser/#/R-CFA-211950 CYP24A1 24-hydroxylates CTL IEA Canis familiaris 58349 R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 58349 R-CFA-2161651 https://reactome.org/PathwayBrowser/#/R-CFA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Canis familiaris 58349 R-CFA-2161745 https://reactome.org/PathwayBrowser/#/R-CFA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Canis familiaris 58349 R-CFA-2161792 https://reactome.org/PathwayBrowser/#/R-CFA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Canis familiaris 58349 R-CFA-2161890 https://reactome.org/PathwayBrowser/#/R-CFA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Canis familiaris 58349 R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Canis familiaris 58349 R-CFA-2161951 https://reactome.org/PathwayBrowser/#/R-CFA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Canis familiaris 58349 R-CFA-2395517 https://reactome.org/PathwayBrowser/#/R-CFA-2395517 NADPH transfers electrons to FDXR IEA Canis familiaris 58349 R-CFA-2464822 https://reactome.org/PathwayBrowser/#/R-CFA-2464822 RDH12 reduces atRAL to atROL IEA Canis familiaris 58349 R-CFA-2465940 https://reactome.org/PathwayBrowser/#/R-CFA-2465940 atRAL is reduced to atROL IEA Canis familiaris 58349 R-CFA-3149518 https://reactome.org/PathwayBrowser/#/R-CFA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Canis familiaris 58349 R-CFA-3149519 https://reactome.org/PathwayBrowser/#/R-CFA-3149519 MMACHC decyanates CNCbl IEA Canis familiaris 58349 R-CFA-3323079 https://reactome.org/PathwayBrowser/#/R-CFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 58349 R-CFA-389540 https://reactome.org/PathwayBrowser/#/R-CFA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 58349 R-CFA-390425 https://reactome.org/PathwayBrowser/#/R-CFA-390425 FAR1 reduces PalmCoA to HXOL IEA Canis familiaris 58349 R-CFA-390438 https://reactome.org/PathwayBrowser/#/R-CFA-390438 FAR2 reduces PalmCoA to HXOL IEA Canis familiaris 58349 R-CFA-418436 https://reactome.org/PathwayBrowser/#/R-CFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Canis familiaris 58349 R-CFA-428123 https://reactome.org/PathwayBrowser/#/R-CFA-428123 KDSR reduces 3-ketosphingoid IEA Canis familiaris 58349 R-CFA-4419979 https://reactome.org/PathwayBrowser/#/R-CFA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Canis familiaris 58349 R-CFA-450971 https://reactome.org/PathwayBrowser/#/R-CFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Canis familiaris 58349 R-CFA-450984 https://reactome.org/PathwayBrowser/#/R-CFA-450984 IDH2 dimer decarboxylates isocitrate IEA Canis familiaris 58349 R-CFA-469659 https://reactome.org/PathwayBrowser/#/R-CFA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Canis familiaris 58349 R-CFA-508040 https://reactome.org/PathwayBrowser/#/R-CFA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Canis familiaris 58349 R-CFA-514604 https://reactome.org/PathwayBrowser/#/R-CFA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Canis familiaris 58349 R-CFA-5218841 https://reactome.org/PathwayBrowser/#/R-CFA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Canis familiaris 58349 R-CFA-5340226 https://reactome.org/PathwayBrowser/#/R-CFA-5340226 CYGB dioxygenates NO IEA Canis familiaris 58349 R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 58349 R-CFA-5419165 https://reactome.org/PathwayBrowser/#/R-CFA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Canis familiaris 58349 R-CFA-5423637 https://reactome.org/PathwayBrowser/#/R-CFA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Canis familiaris 58349 R-CFA-5423647 https://reactome.org/PathwayBrowser/#/R-CFA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Canis familiaris 58349 R-CFA-5423664 https://reactome.org/PathwayBrowser/#/R-CFA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Canis familiaris 58349 R-CFA-5423672 https://reactome.org/PathwayBrowser/#/R-CFA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Canis familiaris 58349 R-CFA-548818 https://reactome.org/PathwayBrowser/#/R-CFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Canis familiaris 58349 R-CFA-548831 https://reactome.org/PathwayBrowser/#/R-CFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Canis familiaris 58349 R-CFA-5602295 https://reactome.org/PathwayBrowser/#/R-CFA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Canis familiaris 58349 R-CFA-5652172 https://reactome.org/PathwayBrowser/#/R-CFA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Canis familiaris 58349 R-CFA-5661240 https://reactome.org/PathwayBrowser/#/R-CFA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Canis familiaris 58349 R-CFA-5661256 https://reactome.org/PathwayBrowser/#/R-CFA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Canis familiaris 58349 R-CFA-5668629 https://reactome.org/PathwayBrowser/#/R-CFA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Canis familiaris 58349 R-CFA-5668718 https://reactome.org/PathwayBrowser/#/R-CFA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 58349 R-CFA-5668731 https://reactome.org/PathwayBrowser/#/R-CFA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 58349 R-CFA-5692232 https://reactome.org/PathwayBrowser/#/R-CFA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Canis familiaris 58349 R-CFA-5692283 https://reactome.org/PathwayBrowser/#/R-CFA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Canis familiaris 58349 R-CFA-5693390 https://reactome.org/PathwayBrowser/#/R-CFA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Canis familiaris 58349 R-CFA-6783955 https://reactome.org/PathwayBrowser/#/R-CFA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 58349 R-CFA-6786239 https://reactome.org/PathwayBrowser/#/R-CFA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Canis familiaris 58349 R-CFA-6787642 https://reactome.org/PathwayBrowser/#/R-CFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Canis familiaris 58349 R-CFA-6789092 https://reactome.org/PathwayBrowser/#/R-CFA-6789092 NOX2 generates superoxide anion from oxygen IEA Canis familiaris 58349 R-CFA-6799722 https://reactome.org/PathwayBrowser/#/R-CFA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Canis familiaris 58349 R-CFA-6807053 https://reactome.org/PathwayBrowser/#/R-CFA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Canis familiaris 58349 R-CFA-6807055 https://reactome.org/PathwayBrowser/#/R-CFA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Canis familiaris 58349 R-CFA-6807064 https://reactome.org/PathwayBrowser/#/R-CFA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Canis familiaris 58349 R-CFA-6807557 https://reactome.org/PathwayBrowser/#/R-CFA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Canis familiaris 58349 R-CFA-6808487 https://reactome.org/PathwayBrowser/#/R-CFA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 58349 R-CFA-6808496 https://reactome.org/PathwayBrowser/#/R-CFA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 58349 R-CFA-70377 https://reactome.org/PathwayBrowser/#/R-CFA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Canis familiaris 58349 R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Canis familiaris 58349 R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Canis familiaris 58349 R-CFA-70938 https://reactome.org/PathwayBrowser/#/R-CFA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Canis familiaris 58349 R-CFA-71200 https://reactome.org/PathwayBrowser/#/R-CFA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Canis familiaris 58349 R-CFA-71299 https://reactome.org/PathwayBrowser/#/R-CFA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Canis familiaris 58349 R-CFA-71682 https://reactome.org/PathwayBrowser/#/R-CFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 58349 R-CFA-73585 https://reactome.org/PathwayBrowser/#/R-CFA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Canis familiaris 58349 R-CFA-73616 https://reactome.org/PathwayBrowser/#/R-CFA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Canis familiaris 58349 R-CFA-74872 https://reactome.org/PathwayBrowser/#/R-CFA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Canis familiaris 58349 R-CFA-75872 https://reactome.org/PathwayBrowser/#/R-CFA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Canis familiaris 58349 R-CFA-75883 https://reactome.org/PathwayBrowser/#/R-CFA-75883 DHRS7B reduces GO3P to HXDG3P IEA Canis familiaris 58349 R-CFA-804969 https://reactome.org/PathwayBrowser/#/R-CFA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Canis familiaris 58349 R-CFA-8862137 https://reactome.org/PathwayBrowser/#/R-CFA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Canis familiaris 58349 R-CFA-8862152 https://reactome.org/PathwayBrowser/#/R-CFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Canis familiaris 58349 R-CFA-8937419 https://reactome.org/PathwayBrowser/#/R-CFA-8937419 CBR3 reduces DOX to DOXOL IEA Canis familiaris 58349 R-CFA-8952873 https://reactome.org/PathwayBrowser/#/R-CFA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Canis familiaris 58349 R-CFA-8955030 https://reactome.org/PathwayBrowser/#/R-CFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Canis familiaris 58349 R-CFA-9012036 https://reactome.org/PathwayBrowser/#/R-CFA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Canis familiaris 58349 R-CFA-9012349 https://reactome.org/PathwayBrowser/#/R-CFA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Canis familiaris 58349 R-CFA-9020255 https://reactome.org/PathwayBrowser/#/R-CFA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Canis familiaris 58349 R-CFA-9020256 https://reactome.org/PathwayBrowser/#/R-CFA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Canis familiaris 58349 R-CFA-9020262 https://reactome.org/PathwayBrowser/#/R-CFA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Canis familiaris 58349 R-CFA-9020277 https://reactome.org/PathwayBrowser/#/R-CFA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Canis familiaris 58349 R-CFA-9020278 https://reactome.org/PathwayBrowser/#/R-CFA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Canis familiaris 58349 R-CFA-9024881 https://reactome.org/PathwayBrowser/#/R-CFA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Canis familiaris 58349 R-CFA-9024983 https://reactome.org/PathwayBrowser/#/R-CFA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Canis familiaris 58349 R-CFA-9025995 https://reactome.org/PathwayBrowser/#/R-CFA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Canis familiaris 58349 R-CFA-9025999 https://reactome.org/PathwayBrowser/#/R-CFA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Canis familiaris 58349 R-CFA-9026007 https://reactome.org/PathwayBrowser/#/R-CFA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Canis familiaris 58349 R-CFA-9027043 https://reactome.org/PathwayBrowser/#/R-CFA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Canis familiaris 58349 R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 58349 R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 58349 R-CFA-917811 https://reactome.org/PathwayBrowser/#/R-CFA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Canis familiaris 58349 R-CFA-9705713 https://reactome.org/PathwayBrowser/#/R-CFA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Canis familiaris 58349 R-CFA-9705714 https://reactome.org/PathwayBrowser/#/R-CFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Canis familiaris 58349 R-CFA-9709098 https://reactome.org/PathwayBrowser/#/R-CFA-9709098 DHFR dimer reduces FOLA to DHF IEA Canis familiaris 58349 R-CFA-9753285 https://reactome.org/PathwayBrowser/#/R-CFA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Canis familiaris 58349 R-CFA-9755937 https://reactome.org/PathwayBrowser/#/R-CFA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Canis familiaris 58349 R-CFA-9756138 https://reactome.org/PathwayBrowser/#/R-CFA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Canis familiaris 58349 R-CFA-9756162 https://reactome.org/PathwayBrowser/#/R-CFA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Canis familiaris 58349 R-CFA-9756169 https://reactome.org/PathwayBrowser/#/R-CFA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Canis familiaris 58349 R-CFA-9756180 https://reactome.org/PathwayBrowser/#/R-CFA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Canis familiaris 58349 R-CFA-9757706 https://reactome.org/PathwayBrowser/#/R-CFA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Canis familiaris 58349 R-CFA-9759259 https://reactome.org/PathwayBrowser/#/R-CFA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Canis familiaris 58349 R-DDI-1475414 https://reactome.org/PathwayBrowser/#/R-DDI-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Dictyostelium discoideum 58349 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 58349 R-DDI-1497869 https://reactome.org/PathwayBrowser/#/R-DDI-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Dictyostelium discoideum 58349 R-DDI-156526 https://reactome.org/PathwayBrowser/#/R-DDI-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Dictyostelium discoideum 58349 R-DDI-1655453 https://reactome.org/PathwayBrowser/#/R-DDI-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Dictyostelium discoideum 58349 R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 58349 R-DDI-191352 https://reactome.org/PathwayBrowser/#/R-DDI-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Dictyostelium discoideum 58349 R-DDI-191402 https://reactome.org/PathwayBrowser/#/R-DDI-191402 Reduction of presqualene diphosphate to form squalene IEA Dictyostelium discoideum 58349 R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 58349 R-DDI-192033 https://reactome.org/PathwayBrowser/#/R-DDI-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Dictyostelium discoideum 58349 R-DDI-192036 https://reactome.org/PathwayBrowser/#/R-DDI-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Dictyostelium discoideum 58349 R-DDI-192067 https://reactome.org/PathwayBrowser/#/R-DDI-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Dictyostelium discoideum 58349 R-DDI-192160 https://reactome.org/PathwayBrowser/#/R-DDI-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Dictyostelium discoideum 58349 R-DDI-193064 https://reactome.org/PathwayBrowser/#/R-DDI-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Dictyostelium discoideum 58349 R-DDI-193746 https://reactome.org/PathwayBrowser/#/R-DDI-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Dictyostelium discoideum 58349 R-DDI-193755 https://reactome.org/PathwayBrowser/#/R-DDI-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Dictyostelium discoideum 58349 R-DDI-193758 https://reactome.org/PathwayBrowser/#/R-DDI-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Dictyostelium discoideum 58349 R-DDI-193781 https://reactome.org/PathwayBrowser/#/R-DDI-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Dictyostelium discoideum 58349 R-DDI-193800 https://reactome.org/PathwayBrowser/#/R-DDI-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Dictyostelium discoideum 58349 R-DDI-193821 https://reactome.org/PathwayBrowser/#/R-DDI-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Dictyostelium discoideum 58349 R-DDI-193824 https://reactome.org/PathwayBrowser/#/R-DDI-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Dictyostelium discoideum 58349 R-DDI-193841 https://reactome.org/PathwayBrowser/#/R-DDI-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Dictyostelium discoideum 58349 R-DDI-193964 https://reactome.org/PathwayBrowser/#/R-DDI-193964 CYP21A2 21-hydroxylates PROG IEA Dictyostelium discoideum 58349 R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 58349 R-DDI-194641 https://reactome.org/PathwayBrowser/#/R-DDI-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 58349 R-DDI-194669 https://reactome.org/PathwayBrowser/#/R-DDI-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 58349 R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 58349 R-DDI-194698 https://reactome.org/PathwayBrowser/#/R-DDI-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Dictyostelium discoideum 58349 R-DDI-196060 https://reactome.org/PathwayBrowser/#/R-DDI-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Dictyostelium discoideum 58349 R-DDI-197198 https://reactome.org/PathwayBrowser/#/R-DDI-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Dictyostelium discoideum 58349 R-DDI-197963 https://reactome.org/PathwayBrowser/#/R-DDI-197963 DHFR2 reduces FOLA to DHF IEA Dictyostelium discoideum 58349 R-DDI-197972 https://reactome.org/PathwayBrowser/#/R-DDI-197972 DHF is reduced to tetrahydrofolate (THF) IEA Dictyostelium discoideum 58349 R-DDI-200644 https://reactome.org/PathwayBrowser/#/R-DDI-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Dictyostelium discoideum 58349 R-DDI-200676 https://reactome.org/PathwayBrowser/#/R-DDI-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Dictyostelium discoideum 58349 R-DDI-200718 https://reactome.org/PathwayBrowser/#/R-DDI-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Dictyostelium discoideum 58349 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 58349 R-DDI-209772 https://reactome.org/PathwayBrowser/#/R-DDI-209772 Thyroxine is deiodinated to triiodothyronine IEA Dictyostelium discoideum 58349 R-DDI-209845 https://reactome.org/PathwayBrowser/#/R-DDI-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Dictyostelium discoideum 58349 R-DDI-2161549 https://reactome.org/PathwayBrowser/#/R-DDI-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Dictyostelium discoideum 58349 R-DDI-2161614 https://reactome.org/PathwayBrowser/#/R-DDI-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Dictyostelium discoideum 58349 R-DDI-2161890 https://reactome.org/PathwayBrowser/#/R-DDI-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Dictyostelium discoideum 58349 R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Dictyostelium discoideum 58349 R-DDI-2395517 https://reactome.org/PathwayBrowser/#/R-DDI-2395517 NADPH transfers electrons to FDXR IEA Dictyostelium discoideum 58349 R-DDI-3149518 https://reactome.org/PathwayBrowser/#/R-DDI-3149518 MTRR reduces cob(II)alamin to meCbl IEA Dictyostelium discoideum 58349 R-DDI-3149519 https://reactome.org/PathwayBrowser/#/R-DDI-3149519 MMACHC decyanates CNCbl IEA Dictyostelium discoideum 58349 R-DDI-3323079 https://reactome.org/PathwayBrowser/#/R-DDI-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 58349 R-DDI-350869 https://reactome.org/PathwayBrowser/#/R-DDI-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Dictyostelium discoideum 58349 R-DDI-389540 https://reactome.org/PathwayBrowser/#/R-DDI-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 58349 R-DDI-390425 https://reactome.org/PathwayBrowser/#/R-DDI-390425 FAR1 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 58349 R-DDI-390438 https://reactome.org/PathwayBrowser/#/R-DDI-390438 FAR2 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 58349 R-DDI-418436 https://reactome.org/PathwayBrowser/#/R-DDI-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Dictyostelium discoideum 58349 R-DDI-428123 https://reactome.org/PathwayBrowser/#/R-DDI-428123 KDSR reduces 3-ketosphingoid IEA Dictyostelium discoideum 58349 R-DDI-4419979 https://reactome.org/PathwayBrowser/#/R-DDI-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Dictyostelium discoideum 58349 R-DDI-450971 https://reactome.org/PathwayBrowser/#/R-DDI-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Dictyostelium discoideum 58349 R-DDI-5419165 https://reactome.org/PathwayBrowser/#/R-DDI-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Dictyostelium discoideum 58349 R-DDI-5423647 https://reactome.org/PathwayBrowser/#/R-DDI-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Dictyostelium discoideum 58349 R-DDI-548818 https://reactome.org/PathwayBrowser/#/R-DDI-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Dictyostelium discoideum 58349 R-DDI-548831 https://reactome.org/PathwayBrowser/#/R-DDI-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Dictyostelium discoideum 58349 R-DDI-5615668 https://reactome.org/PathwayBrowser/#/R-DDI-5615668 AKR1C3 reduces atRAL to atROL IEA Dictyostelium discoideum 58349 R-DDI-5652172 https://reactome.org/PathwayBrowser/#/R-DDI-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Dictyostelium discoideum 58349 R-DDI-5661256 https://reactome.org/PathwayBrowser/#/R-DDI-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Dictyostelium discoideum 58349 R-DDI-5692232 https://reactome.org/PathwayBrowser/#/R-DDI-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Dictyostelium discoideum 58349 R-DDI-5692283 https://reactome.org/PathwayBrowser/#/R-DDI-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Dictyostelium discoideum 58349 R-DDI-5696822 https://reactome.org/PathwayBrowser/#/R-DDI-5696822 AKR1B15 reduces EST17b to E1 IEA Dictyostelium discoideum 58349 R-DDI-6783955 https://reactome.org/PathwayBrowser/#/R-DDI-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 58349 R-DDI-6787642 https://reactome.org/PathwayBrowser/#/R-DDI-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Dictyostelium discoideum 58349 R-DDI-6799722 https://reactome.org/PathwayBrowser/#/R-DDI-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Dictyostelium discoideum 58349 R-DDI-6807557 https://reactome.org/PathwayBrowser/#/R-DDI-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Dictyostelium discoideum 58349 R-DDI-70377 https://reactome.org/PathwayBrowser/#/R-DDI-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Dictyostelium discoideum 58349 R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Dictyostelium discoideum 58349 R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Dictyostelium discoideum 58349 R-DDI-70938 https://reactome.org/PathwayBrowser/#/R-DDI-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Dictyostelium discoideum 58349 R-DDI-71200 https://reactome.org/PathwayBrowser/#/R-DDI-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Dictyostelium discoideum 58349 R-DDI-71299 https://reactome.org/PathwayBrowser/#/R-DDI-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 58349 R-DDI-71682 https://reactome.org/PathwayBrowser/#/R-DDI-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 58349 R-DDI-73585 https://reactome.org/PathwayBrowser/#/R-DDI-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Dictyostelium discoideum 58349 R-DDI-73616 https://reactome.org/PathwayBrowser/#/R-DDI-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Dictyostelium discoideum 58349 R-DDI-75872 https://reactome.org/PathwayBrowser/#/R-DDI-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Dictyostelium discoideum 58349 R-DDI-804969 https://reactome.org/PathwayBrowser/#/R-DDI-804969 HSD17B1 hydrogenates E1 to EST17b IEA Dictyostelium discoideum 58349 R-DDI-8862152 https://reactome.org/PathwayBrowser/#/R-DDI-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Dictyostelium discoideum 58349 R-DDI-8865107 https://reactome.org/PathwayBrowser/#/R-DDI-8865107 MICAL1 produces NADP+, H2O2 IEA Dictyostelium discoideum 58349 R-DDI-8952873 https://reactome.org/PathwayBrowser/#/R-DDI-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Dictyostelium discoideum 58349 R-DDI-9020255 https://reactome.org/PathwayBrowser/#/R-DDI-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Dictyostelium discoideum 58349 R-DDI-9020256 https://reactome.org/PathwayBrowser/#/R-DDI-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Dictyostelium discoideum 58349 R-DDI-9020262 https://reactome.org/PathwayBrowser/#/R-DDI-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Dictyostelium discoideum 58349 R-DDI-9020277 https://reactome.org/PathwayBrowser/#/R-DDI-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Dictyostelium discoideum 58349 R-DDI-9020278 https://reactome.org/PathwayBrowser/#/R-DDI-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Dictyostelium discoideum 58349 R-DDI-9024881 https://reactome.org/PathwayBrowser/#/R-DDI-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Dictyostelium discoideum 58349 R-DDI-9024983 https://reactome.org/PathwayBrowser/#/R-DDI-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Dictyostelium discoideum 58349 R-DDI-9025995 https://reactome.org/PathwayBrowser/#/R-DDI-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Dictyostelium discoideum 58349 R-DDI-9025999 https://reactome.org/PathwayBrowser/#/R-DDI-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Dictyostelium discoideum 58349 R-DDI-9026007 https://reactome.org/PathwayBrowser/#/R-DDI-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Dictyostelium discoideum 58349 R-DDI-9027043 https://reactome.org/PathwayBrowser/#/R-DDI-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Dictyostelium discoideum 58349 R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 58349 R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 58349 R-DDI-9705714 https://reactome.org/PathwayBrowser/#/R-DDI-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Dictyostelium discoideum 58349 R-DDI-9709098 https://reactome.org/PathwayBrowser/#/R-DDI-9709098 DHFR dimer reduces FOLA to DHF IEA Dictyostelium discoideum 58349 R-DDI-9753285 https://reactome.org/PathwayBrowser/#/R-DDI-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Dictyostelium discoideum 58349 R-DDI-9758682 https://reactome.org/PathwayBrowser/#/R-DDI-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Dictyostelium discoideum 58349 R-DME-1475414 https://reactome.org/PathwayBrowser/#/R-DME-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Drosophila melanogaster 58349 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 58349 R-DME-1497869 https://reactome.org/PathwayBrowser/#/R-DME-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Drosophila melanogaster 58349 R-DME-156526 https://reactome.org/PathwayBrowser/#/R-DME-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Drosophila melanogaster 58349 R-DME-189384 https://reactome.org/PathwayBrowser/#/R-DME-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Drosophila melanogaster 58349 R-DME-189398 https://reactome.org/PathwayBrowser/#/R-DME-189398 HMOX1 dimer, HMOX2 cleave heme IEA Drosophila melanogaster 58349 R-DME-191352 https://reactome.org/PathwayBrowser/#/R-DME-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Drosophila melanogaster 58349 R-DME-192033 https://reactome.org/PathwayBrowser/#/R-DME-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Drosophila melanogaster 58349 R-DME-192036 https://reactome.org/PathwayBrowser/#/R-DME-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Drosophila melanogaster 58349 R-DME-192067 https://reactome.org/PathwayBrowser/#/R-DME-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Drosophila melanogaster 58349 R-DME-192160 https://reactome.org/PathwayBrowser/#/R-DME-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Drosophila melanogaster 58349 R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 58349 R-DME-193064 https://reactome.org/PathwayBrowser/#/R-DME-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Drosophila melanogaster 58349 R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 58349 R-DME-193746 https://reactome.org/PathwayBrowser/#/R-DME-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Drosophila melanogaster 58349 R-DME-193755 https://reactome.org/PathwayBrowser/#/R-DME-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Drosophila melanogaster 58349 R-DME-193758 https://reactome.org/PathwayBrowser/#/R-DME-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Drosophila melanogaster 58349 R-DME-193781 https://reactome.org/PathwayBrowser/#/R-DME-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Drosophila melanogaster 58349 R-DME-193800 https://reactome.org/PathwayBrowser/#/R-DME-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Drosophila melanogaster 58349 R-DME-193821 https://reactome.org/PathwayBrowser/#/R-DME-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Drosophila melanogaster 58349 R-DME-193824 https://reactome.org/PathwayBrowser/#/R-DME-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Drosophila melanogaster 58349 R-DME-193841 https://reactome.org/PathwayBrowser/#/R-DME-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Drosophila melanogaster 58349 R-DME-194023 https://reactome.org/PathwayBrowser/#/R-DME-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Drosophila melanogaster 58349 R-DME-194698 https://reactome.org/PathwayBrowser/#/R-DME-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Drosophila melanogaster 58349 R-DME-196060 https://reactome.org/PathwayBrowser/#/R-DME-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Drosophila melanogaster 58349 R-DME-197198 https://reactome.org/PathwayBrowser/#/R-DME-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 58349 R-DME-197963 https://reactome.org/PathwayBrowser/#/R-DME-197963 DHFR2 reduces FOLA to DHF IEA Drosophila melanogaster 58349 R-DME-197972 https://reactome.org/PathwayBrowser/#/R-DME-197972 DHF is reduced to tetrahydrofolate (THF) IEA Drosophila melanogaster 58349 R-DME-200644 https://reactome.org/PathwayBrowser/#/R-DME-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Drosophila melanogaster 58349 R-DME-200676 https://reactome.org/PathwayBrowser/#/R-DME-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Drosophila melanogaster 58349 R-DME-200718 https://reactome.org/PathwayBrowser/#/R-DME-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Drosophila melanogaster 58349 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 58349 R-DME-209845 https://reactome.org/PathwayBrowser/#/R-DME-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Drosophila melanogaster 58349 R-DME-2161549 https://reactome.org/PathwayBrowser/#/R-DME-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Drosophila melanogaster 58349 R-DME-2161614 https://reactome.org/PathwayBrowser/#/R-DME-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Drosophila melanogaster 58349 R-DME-2161890 https://reactome.org/PathwayBrowser/#/R-DME-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Drosophila melanogaster 58349 R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Drosophila melanogaster 58349 R-DME-2395517 https://reactome.org/PathwayBrowser/#/R-DME-2395517 NADPH transfers electrons to FDXR IEA Drosophila melanogaster 58349 R-DME-2464822 https://reactome.org/PathwayBrowser/#/R-DME-2464822 RDH12 reduces atRAL to atROL IEA Drosophila melanogaster 58349 R-DME-2465940 https://reactome.org/PathwayBrowser/#/R-DME-2465940 atRAL is reduced to atROL IEA Drosophila melanogaster 58349 R-DME-2855252 https://reactome.org/PathwayBrowser/#/R-DME-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 58349 R-DME-3323050 https://reactome.org/PathwayBrowser/#/R-DME-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Drosophila melanogaster 58349 R-DME-389540 https://reactome.org/PathwayBrowser/#/R-DME-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 58349 R-DME-390425 https://reactome.org/PathwayBrowser/#/R-DME-390425 FAR1 reduces PalmCoA to HXOL IEA Drosophila melanogaster 58349 R-DME-390438 https://reactome.org/PathwayBrowser/#/R-DME-390438 FAR2 reduces PalmCoA to HXOL IEA Drosophila melanogaster 58349 R-DME-418436 https://reactome.org/PathwayBrowser/#/R-DME-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Drosophila melanogaster 58349 R-DME-428123 https://reactome.org/PathwayBrowser/#/R-DME-428123 KDSR reduces 3-ketosphingoid IEA Drosophila melanogaster 58349 R-DME-4419979 https://reactome.org/PathwayBrowser/#/R-DME-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Drosophila melanogaster 58349 R-DME-508040 https://reactome.org/PathwayBrowser/#/R-DME-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Drosophila melanogaster 58349 R-DME-5419165 https://reactome.org/PathwayBrowser/#/R-DME-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Drosophila melanogaster 58349 R-DME-5423647 https://reactome.org/PathwayBrowser/#/R-DME-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Drosophila melanogaster 58349 R-DME-548818 https://reactome.org/PathwayBrowser/#/R-DME-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Drosophila melanogaster 58349 R-DME-548831 https://reactome.org/PathwayBrowser/#/R-DME-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Drosophila melanogaster 58349 R-DME-5615668 https://reactome.org/PathwayBrowser/#/R-DME-5615668 AKR1C3 reduces atRAL to atROL IEA Drosophila melanogaster 58349 R-DME-5652172 https://reactome.org/PathwayBrowser/#/R-DME-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Drosophila melanogaster 58349 R-DME-5661240 https://reactome.org/PathwayBrowser/#/R-DME-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Drosophila melanogaster 58349 R-DME-5661256 https://reactome.org/PathwayBrowser/#/R-DME-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Drosophila melanogaster 58349 R-DME-5692232 https://reactome.org/PathwayBrowser/#/R-DME-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Drosophila melanogaster 58349 R-DME-5692283 https://reactome.org/PathwayBrowser/#/R-DME-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Drosophila melanogaster 58349 R-DME-5693390 https://reactome.org/PathwayBrowser/#/R-DME-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Drosophila melanogaster 58349 R-DME-5696822 https://reactome.org/PathwayBrowser/#/R-DME-5696822 AKR1B15 reduces EST17b to E1 IEA Drosophila melanogaster 58349 R-DME-6786239 https://reactome.org/PathwayBrowser/#/R-DME-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Drosophila melanogaster 58349 R-DME-6787642 https://reactome.org/PathwayBrowser/#/R-DME-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Drosophila melanogaster 58349 R-DME-6807557 https://reactome.org/PathwayBrowser/#/R-DME-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Drosophila melanogaster 58349 R-DME-6808487 https://reactome.org/PathwayBrowser/#/R-DME-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 58349 R-DME-6808496 https://reactome.org/PathwayBrowser/#/R-DME-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 58349 R-DME-70377 https://reactome.org/PathwayBrowser/#/R-DME-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Drosophila melanogaster 58349 R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Drosophila melanogaster 58349 R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Drosophila melanogaster 58349 R-DME-70938 https://reactome.org/PathwayBrowser/#/R-DME-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Drosophila melanogaster 58349 R-DME-71200 https://reactome.org/PathwayBrowser/#/R-DME-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Drosophila melanogaster 58349 R-DME-71299 https://reactome.org/PathwayBrowser/#/R-DME-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Drosophila melanogaster 58349 R-DME-73585 https://reactome.org/PathwayBrowser/#/R-DME-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Drosophila melanogaster 58349 R-DME-73616 https://reactome.org/PathwayBrowser/#/R-DME-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Drosophila melanogaster 58349 R-DME-74872 https://reactome.org/PathwayBrowser/#/R-DME-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 58349 R-DME-75872 https://reactome.org/PathwayBrowser/#/R-DME-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Drosophila melanogaster 58349 R-DME-75883 https://reactome.org/PathwayBrowser/#/R-DME-75883 DHRS7B reduces GO3P to HXDG3P IEA Drosophila melanogaster 58349 R-DME-8862137 https://reactome.org/PathwayBrowser/#/R-DME-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Drosophila melanogaster 58349 R-DME-8952873 https://reactome.org/PathwayBrowser/#/R-DME-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Drosophila melanogaster 58349 R-DME-8955030 https://reactome.org/PathwayBrowser/#/R-DME-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 58349 R-DME-9012036 https://reactome.org/PathwayBrowser/#/R-DME-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 58349 R-DME-9012349 https://reactome.org/PathwayBrowser/#/R-DME-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 58349 R-DME-9027043 https://reactome.org/PathwayBrowser/#/R-DME-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Drosophila melanogaster 58349 R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 58349 R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 58349 R-DME-9705714 https://reactome.org/PathwayBrowser/#/R-DME-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Drosophila melanogaster 58349 R-DME-9709098 https://reactome.org/PathwayBrowser/#/R-DME-9709098 DHFR dimer reduces FOLA to DHF IEA Drosophila melanogaster 58349 R-DME-9753285 https://reactome.org/PathwayBrowser/#/R-DME-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Drosophila melanogaster 58349 R-DME-975629 https://reactome.org/PathwayBrowser/#/R-DME-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 58349 R-DME-9758682 https://reactome.org/PathwayBrowser/#/R-DME-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Drosophila melanogaster 58349 R-DME-9759259 https://reactome.org/PathwayBrowser/#/R-DME-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Drosophila melanogaster 58349 R-DRE-1222376 https://reactome.org/PathwayBrowser/#/R-DRE-1222376 NOX2 generates superoxide from oxygen IEA Danio rerio 58349 R-DRE-1475414 https://reactome.org/PathwayBrowser/#/R-DRE-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Danio rerio 58349 R-DRE-1497869 https://reactome.org/PathwayBrowser/#/R-DRE-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Danio rerio 58349 R-DRE-156526 https://reactome.org/PathwayBrowser/#/R-DRE-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Danio rerio 58349 R-DRE-1655453 https://reactome.org/PathwayBrowser/#/R-DRE-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Danio rerio 58349 R-DRE-189384 https://reactome.org/PathwayBrowser/#/R-DRE-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Danio rerio 58349 R-DRE-189398 https://reactome.org/PathwayBrowser/#/R-DRE-189398 HMOX1 dimer, HMOX2 cleave heme IEA Danio rerio 58349 R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 58349 R-DRE-191352 https://reactome.org/PathwayBrowser/#/R-DRE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Danio rerio 58349 R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 58349 R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 58349 R-DRE-192157 https://reactome.org/PathwayBrowser/#/R-DRE-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Danio rerio 58349 R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 58349 R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 58349 R-DRE-193064 https://reactome.org/PathwayBrowser/#/R-DRE-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Danio rerio 58349 R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 58349 R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 58349 R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 58349 R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 58349 R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 58349 R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 58349 R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 58349 R-DRE-193709 https://reactome.org/PathwayBrowser/#/R-DRE-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Danio rerio 58349 R-DRE-193845 https://reactome.org/PathwayBrowser/#/R-DRE-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Danio rerio 58349 R-DRE-194023 https://reactome.org/PathwayBrowser/#/R-DRE-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Danio rerio 58349 R-DRE-194632 https://reactome.org/PathwayBrowser/#/R-DRE-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Danio rerio 58349 R-DRE-194641 https://reactome.org/PathwayBrowser/#/R-DRE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 58349 R-DRE-194669 https://reactome.org/PathwayBrowser/#/R-DRE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 58349 R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 58349 R-DRE-194689 https://reactome.org/PathwayBrowser/#/R-DRE-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Danio rerio 58349 R-DRE-194698 https://reactome.org/PathwayBrowser/#/R-DRE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Danio rerio 58349 R-DRE-195664 https://reactome.org/PathwayBrowser/#/R-DRE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Danio rerio 58349 R-DRE-196060 https://reactome.org/PathwayBrowser/#/R-DRE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Danio rerio 58349 R-DRE-196402 https://reactome.org/PathwayBrowser/#/R-DRE-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Danio rerio 58349 R-DRE-196417 https://reactome.org/PathwayBrowser/#/R-DRE-196417 Reduction of desmosterol to cholesterol IEA Danio rerio 58349 R-DRE-197198 https://reactome.org/PathwayBrowser/#/R-DRE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Danio rerio 58349 R-DRE-197963 https://reactome.org/PathwayBrowser/#/R-DRE-197963 DHFR2 reduces FOLA to DHF IEA Danio rerio 58349 R-DRE-197972 https://reactome.org/PathwayBrowser/#/R-DRE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Danio rerio 58349 R-DRE-200644 https://reactome.org/PathwayBrowser/#/R-DRE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Danio rerio 58349 R-DRE-200676 https://reactome.org/PathwayBrowser/#/R-DRE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Danio rerio 58349 R-DRE-200718 https://reactome.org/PathwayBrowser/#/R-DRE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Danio rerio 58349 R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 58349 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 58349 R-DRE-211873 https://reactome.org/PathwayBrowser/#/R-DRE-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Danio rerio 58349 R-DRE-211923 https://reactome.org/PathwayBrowser/#/R-DRE-211923 CYP26C1 4-hydroxylates 9cRA IEA Danio rerio 58349 R-DRE-211950 https://reactome.org/PathwayBrowser/#/R-DRE-211950 CYP24A1 24-hydroxylates CTL IEA Danio rerio 58349 R-DRE-211951 https://reactome.org/PathwayBrowser/#/R-DRE-211951 CYP1B1 4-hydroxylates EST17b IEA Danio rerio 58349 R-DRE-2161651 https://reactome.org/PathwayBrowser/#/R-DRE-2161651 PGE2 is converted to PGF2a by CBR1 IEA Danio rerio 58349 R-DRE-2161745 https://reactome.org/PathwayBrowser/#/R-DRE-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Danio rerio 58349 R-DRE-2161792 https://reactome.org/PathwayBrowser/#/R-DRE-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Danio rerio 58349 R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio 58349 R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Danio rerio 58349 R-DRE-2161951 https://reactome.org/PathwayBrowser/#/R-DRE-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Danio rerio 58349 R-DRE-2395517 https://reactome.org/PathwayBrowser/#/R-DRE-2395517 NADPH transfers electrons to FDXR IEA Danio rerio 58349 R-DRE-2464822 https://reactome.org/PathwayBrowser/#/R-DRE-2464822 RDH12 reduces atRAL to atROL IEA Danio rerio 58349 R-DRE-2465940 https://reactome.org/PathwayBrowser/#/R-DRE-2465940 atRAL is reduced to atROL IEA Danio rerio 58349 R-DRE-2855252 https://reactome.org/PathwayBrowser/#/R-DRE-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Danio rerio 58349 R-DRE-3149519 https://reactome.org/PathwayBrowser/#/R-DRE-3149519 MMACHC decyanates CNCbl IEA Danio rerio 58349 R-DRE-389540 https://reactome.org/PathwayBrowser/#/R-DRE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 58349 R-DRE-390438 https://reactome.org/PathwayBrowser/#/R-DRE-390438 FAR2 reduces PalmCoA to HXOL IEA Danio rerio 58349 R-DRE-418436 https://reactome.org/PathwayBrowser/#/R-DRE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Danio rerio 58349 R-DRE-4419979 https://reactome.org/PathwayBrowser/#/R-DRE-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Danio rerio 58349 R-DRE-450971 https://reactome.org/PathwayBrowser/#/R-DRE-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Danio rerio 58349 R-DRE-450984 https://reactome.org/PathwayBrowser/#/R-DRE-450984 IDH2 dimer decarboxylates isocitrate IEA Danio rerio 58349 R-DRE-469659 https://reactome.org/PathwayBrowser/#/R-DRE-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Danio rerio 58349 R-DRE-514604 https://reactome.org/PathwayBrowser/#/R-DRE-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Danio rerio 58349 R-DRE-5218841 https://reactome.org/PathwayBrowser/#/R-DRE-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Danio rerio 58349 R-DRE-5340226 https://reactome.org/PathwayBrowser/#/R-DRE-5340226 CYGB dioxygenates NO IEA Danio rerio 58349 R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 58349 R-DRE-5419165 https://reactome.org/PathwayBrowser/#/R-DRE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Danio rerio 58349 R-DRE-5423637 https://reactome.org/PathwayBrowser/#/R-DRE-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Danio rerio 58349 R-DRE-5423647 https://reactome.org/PathwayBrowser/#/R-DRE-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Danio rerio 58349 R-DRE-5423664 https://reactome.org/PathwayBrowser/#/R-DRE-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Danio rerio 58349 R-DRE-5423672 https://reactome.org/PathwayBrowser/#/R-DRE-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Danio rerio 58349 R-DRE-5423678 https://reactome.org/PathwayBrowser/#/R-DRE-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Danio rerio 58349 R-DRE-548818 https://reactome.org/PathwayBrowser/#/R-DRE-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Danio rerio 58349 R-DRE-5602295 https://reactome.org/PathwayBrowser/#/R-DRE-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Danio rerio 58349 R-DRE-5652172 https://reactome.org/PathwayBrowser/#/R-DRE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Danio rerio 58349 R-DRE-5661240 https://reactome.org/PathwayBrowser/#/R-DRE-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Danio rerio 58349 R-DRE-5661256 https://reactome.org/PathwayBrowser/#/R-DRE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Danio rerio 58349 R-DRE-5668629 https://reactome.org/PathwayBrowser/#/R-DRE-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Danio rerio 58349 R-DRE-5668718 https://reactome.org/PathwayBrowser/#/R-DRE-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 58349 R-DRE-5668731 https://reactome.org/PathwayBrowser/#/R-DRE-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 58349 R-DRE-5692232 https://reactome.org/PathwayBrowser/#/R-DRE-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Danio rerio 58349 R-DRE-5692283 https://reactome.org/PathwayBrowser/#/R-DRE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Danio rerio 58349 R-DRE-5696822 https://reactome.org/PathwayBrowser/#/R-DRE-5696822 AKR1B15 reduces EST17b to E1 IEA Danio rerio 58349 R-DRE-6783955 https://reactome.org/PathwayBrowser/#/R-DRE-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 58349 R-DRE-6786239 https://reactome.org/PathwayBrowser/#/R-DRE-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Danio rerio 58349 R-DRE-6787642 https://reactome.org/PathwayBrowser/#/R-DRE-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Danio rerio 58349 R-DRE-6789092 https://reactome.org/PathwayBrowser/#/R-DRE-6789092 NOX2 generates superoxide anion from oxygen IEA Danio rerio 58349 R-DRE-6807053 https://reactome.org/PathwayBrowser/#/R-DRE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Danio rerio 58349 R-DRE-6807055 https://reactome.org/PathwayBrowser/#/R-DRE-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Danio rerio 58349 R-DRE-6807064 https://reactome.org/PathwayBrowser/#/R-DRE-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Danio rerio 58349 R-DRE-6808496 https://reactome.org/PathwayBrowser/#/R-DRE-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Danio rerio 58349 R-DRE-6810594 https://reactome.org/PathwayBrowser/#/R-DRE-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Danio rerio 58349 R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Danio rerio 58349 R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Danio rerio 58349 R-DRE-70938 https://reactome.org/PathwayBrowser/#/R-DRE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Danio rerio 58349 R-DRE-71200 https://reactome.org/PathwayBrowser/#/R-DRE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Danio rerio 58349 R-DRE-71299 https://reactome.org/PathwayBrowser/#/R-DRE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Danio rerio 58349 R-DRE-73585 https://reactome.org/PathwayBrowser/#/R-DRE-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Danio rerio 58349 R-DRE-73616 https://reactome.org/PathwayBrowser/#/R-DRE-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Danio rerio 58349 R-DRE-74872 https://reactome.org/PathwayBrowser/#/R-DRE-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Danio rerio 58349 R-DRE-75872 https://reactome.org/PathwayBrowser/#/R-DRE-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Danio rerio 58349 R-DRE-75883 https://reactome.org/PathwayBrowser/#/R-DRE-75883 DHRS7B reduces GO3P to HXDG3P IEA Danio rerio 58349 R-DRE-8862152 https://reactome.org/PathwayBrowser/#/R-DRE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Danio rerio 58349 R-DRE-8865107 https://reactome.org/PathwayBrowser/#/R-DRE-8865107 MICAL1 produces NADP+, H2O2 IEA Danio rerio 58349 R-DRE-8937419 https://reactome.org/PathwayBrowser/#/R-DRE-8937419 CBR3 reduces DOX to DOXOL IEA Danio rerio 58349 R-DRE-8952873 https://reactome.org/PathwayBrowser/#/R-DRE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Danio rerio 58349 R-DRE-9012036 https://reactome.org/PathwayBrowser/#/R-DRE-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Danio rerio 58349 R-DRE-9012349 https://reactome.org/PathwayBrowser/#/R-DRE-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Danio rerio 58349 R-DRE-9020255 https://reactome.org/PathwayBrowser/#/R-DRE-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Danio rerio 58349 R-DRE-9020256 https://reactome.org/PathwayBrowser/#/R-DRE-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Danio rerio 58349 R-DRE-9020262 https://reactome.org/PathwayBrowser/#/R-DRE-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Danio rerio 58349 R-DRE-9020277 https://reactome.org/PathwayBrowser/#/R-DRE-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Danio rerio 58349 R-DRE-9020278 https://reactome.org/PathwayBrowser/#/R-DRE-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Danio rerio 58349 R-DRE-9024881 https://reactome.org/PathwayBrowser/#/R-DRE-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Danio rerio 58349 R-DRE-9024983 https://reactome.org/PathwayBrowser/#/R-DRE-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Danio rerio 58349 R-DRE-9025995 https://reactome.org/PathwayBrowser/#/R-DRE-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Danio rerio 58349 R-DRE-9025999 https://reactome.org/PathwayBrowser/#/R-DRE-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Danio rerio 58349 R-DRE-9026007 https://reactome.org/PathwayBrowser/#/R-DRE-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Danio rerio 58349 R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio 58349 R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 58349 R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 58349 R-DRE-9037761 https://reactome.org/PathwayBrowser/#/R-DRE-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Danio rerio 58349 R-DRE-9705713 https://reactome.org/PathwayBrowser/#/R-DRE-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Danio rerio 58349 R-DRE-9705714 https://reactome.org/PathwayBrowser/#/R-DRE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Danio rerio 58349 R-DRE-9709098 https://reactome.org/PathwayBrowser/#/R-DRE-9709098 DHFR dimer reduces FOLA to DHF IEA Danio rerio 58349 R-DRE-9753285 https://reactome.org/PathwayBrowser/#/R-DRE-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Danio rerio 58349 R-DRE-9755937 https://reactome.org/PathwayBrowser/#/R-DRE-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Danio rerio 58349 R-DRE-9756138 https://reactome.org/PathwayBrowser/#/R-DRE-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Danio rerio 58349 R-DRE-9756162 https://reactome.org/PathwayBrowser/#/R-DRE-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Danio rerio 58349 R-DRE-9756169 https://reactome.org/PathwayBrowser/#/R-DRE-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Danio rerio 58349 R-DRE-9756180 https://reactome.org/PathwayBrowser/#/R-DRE-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Danio rerio 58349 R-DRE-975629 https://reactome.org/PathwayBrowser/#/R-DRE-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Danio rerio 58349 R-DRE-9757706 https://reactome.org/PathwayBrowser/#/R-DRE-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Danio rerio 58349 R-DRE-9759259 https://reactome.org/PathwayBrowser/#/R-DRE-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Danio rerio 58349 R-ECO-1222667 https://reactome.org/PathwayBrowser/#/R-ECO-1222667 Iron is reduced and separates from enterobactin TAS Escherichia coli 58349 R-GGA-1222376 https://reactome.org/PathwayBrowser/#/R-GGA-1222376 NOX2 generates superoxide from oxygen IEA Gallus gallus 58349 R-GGA-1475414 https://reactome.org/PathwayBrowser/#/R-GGA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Gallus gallus 58349 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 58349 R-GGA-1497869 https://reactome.org/PathwayBrowser/#/R-GGA-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Gallus gallus 58349 R-GGA-156526 https://reactome.org/PathwayBrowser/#/R-GGA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Gallus gallus 58349 R-GGA-189384 https://reactome.org/PathwayBrowser/#/R-GGA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Gallus gallus 58349 R-GGA-189398 https://reactome.org/PathwayBrowser/#/R-GGA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Gallus gallus 58349 R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 58349 R-GGA-191352 https://reactome.org/PathwayBrowser/#/R-GGA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Gallus gallus 58349 R-GGA-191402 https://reactome.org/PathwayBrowser/#/R-GGA-191402 Reduction of presqualene diphosphate to form squalene IEA Gallus gallus 58349 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 58349 R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 58349 R-GGA-192033 https://reactome.org/PathwayBrowser/#/R-GGA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Gallus gallus 58349 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 58349 R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 58349 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 58349 R-GGA-192067 https://reactome.org/PathwayBrowser/#/R-GGA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Gallus gallus 58349 R-GGA-192178 https://reactome.org/PathwayBrowser/#/R-GGA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Gallus gallus 58349 R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 58349 R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 58349 R-GGA-193064 https://reactome.org/PathwayBrowser/#/R-GGA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Gallus gallus 58349 R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 58349 R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 58349 R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 58349 R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 58349 R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 58349 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 58349 R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 58349 R-GGA-193746 https://reactome.org/PathwayBrowser/#/R-GGA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Gallus gallus 58349 R-GGA-193755 https://reactome.org/PathwayBrowser/#/R-GGA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Gallus gallus 58349 R-GGA-193821 https://reactome.org/PathwayBrowser/#/R-GGA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Gallus gallus 58349 R-GGA-193824 https://reactome.org/PathwayBrowser/#/R-GGA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Gallus gallus 58349 R-GGA-193964 https://reactome.org/PathwayBrowser/#/R-GGA-193964 CYP21A2 21-hydroxylates PROG IEA Gallus gallus 58349 R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 58349 R-GGA-194023 https://reactome.org/PathwayBrowser/#/R-GGA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Gallus gallus 58349 R-GGA-194632 https://reactome.org/PathwayBrowser/#/R-GGA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Gallus gallus 58349 R-GGA-194641 https://reactome.org/PathwayBrowser/#/R-GGA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 58349 R-GGA-194669 https://reactome.org/PathwayBrowser/#/R-GGA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 58349 R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 58349 R-GGA-194689 https://reactome.org/PathwayBrowser/#/R-GGA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 58349 R-GGA-195664 https://reactome.org/PathwayBrowser/#/R-GGA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Gallus gallus 58349 R-GGA-196060 https://reactome.org/PathwayBrowser/#/R-GGA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Gallus gallus 58349 R-GGA-196402 https://reactome.org/PathwayBrowser/#/R-GGA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Gallus gallus 58349 R-GGA-196417 https://reactome.org/PathwayBrowser/#/R-GGA-196417 Reduction of desmosterol to cholesterol IEA Gallus gallus 58349 R-GGA-197198 https://reactome.org/PathwayBrowser/#/R-GGA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Gallus gallus 58349 R-GGA-197963 https://reactome.org/PathwayBrowser/#/R-GGA-197963 DHFR2 reduces FOLA to DHF IEA Gallus gallus 58349 R-GGA-197972 https://reactome.org/PathwayBrowser/#/R-GGA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Gallus gallus 58349 R-GGA-200644 https://reactome.org/PathwayBrowser/#/R-GGA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Gallus gallus 58349 R-GGA-200676 https://reactome.org/PathwayBrowser/#/R-GGA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Gallus gallus 58349 R-GGA-200718 https://reactome.org/PathwayBrowser/#/R-GGA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Gallus gallus 58349 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 58349 R-GGA-209772 https://reactome.org/PathwayBrowser/#/R-GGA-209772 Thyroxine is deiodinated to triiodothyronine IEA Gallus gallus 58349 R-GGA-209845 https://reactome.org/PathwayBrowser/#/R-GGA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Gallus gallus 58349 R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus 58349 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 58349 R-GGA-2161651 https://reactome.org/PathwayBrowser/#/R-GGA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Gallus gallus 58349 R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus 58349 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Gallus gallus 58349 R-GGA-2161951 https://reactome.org/PathwayBrowser/#/R-GGA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Gallus gallus 58349 R-GGA-2395517 https://reactome.org/PathwayBrowser/#/R-GGA-2395517 NADPH transfers electrons to FDXR IEA Gallus gallus 58349 R-GGA-2464822 https://reactome.org/PathwayBrowser/#/R-GGA-2464822 RDH12 reduces atRAL to atROL IEA Gallus gallus 58349 R-GGA-2465940 https://reactome.org/PathwayBrowser/#/R-GGA-2465940 atRAL is reduced to atROL IEA Gallus gallus 58349 R-GGA-2855252 https://reactome.org/PathwayBrowser/#/R-GGA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Gallus gallus 58349 R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus 58349 R-GGA-3149519 https://reactome.org/PathwayBrowser/#/R-GGA-3149519 MMACHC decyanates CNCbl IEA Gallus gallus 58349 R-GGA-3323050 https://reactome.org/PathwayBrowser/#/R-GGA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Gallus gallus 58349 R-GGA-3323079 https://reactome.org/PathwayBrowser/#/R-GGA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 58349 R-GGA-389540 https://reactome.org/PathwayBrowser/#/R-GGA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 58349 R-GGA-390425 https://reactome.org/PathwayBrowser/#/R-GGA-390425 FAR1 reduces PalmCoA to HXOL IEA Gallus gallus 58349 R-GGA-390438 https://reactome.org/PathwayBrowser/#/R-GGA-390438 FAR2 reduces PalmCoA to HXOL IEA Gallus gallus 58349 R-GGA-418436 https://reactome.org/PathwayBrowser/#/R-GGA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Gallus gallus 58349 R-GGA-433576 https://reactome.org/PathwayBrowser/#/R-GGA-433576 3-dehydrosphinganine + NADPH + H+ => sphinganine + NADP+ IEA Gallus gallus 58349 R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 58349 R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 58349 R-GGA-4419979 https://reactome.org/PathwayBrowser/#/R-GGA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Gallus gallus 58349 R-GGA-450971 https://reactome.org/PathwayBrowser/#/R-GGA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Gallus gallus 58349 R-GGA-450984 https://reactome.org/PathwayBrowser/#/R-GGA-450984 IDH2 dimer decarboxylates isocitrate IEA Gallus gallus 58349 R-GGA-469659 https://reactome.org/PathwayBrowser/#/R-GGA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Gallus gallus 58349 R-GGA-508040 https://reactome.org/PathwayBrowser/#/R-GGA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Gallus gallus 58349 R-GGA-514604 https://reactome.org/PathwayBrowser/#/R-GGA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Gallus gallus 58349 R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus 58349 R-GGA-5263614 https://reactome.org/PathwayBrowser/#/R-GGA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Gallus gallus 58349 R-GGA-5263616 https://reactome.org/PathwayBrowser/#/R-GGA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Gallus gallus 58349 R-GGA-5340226 https://reactome.org/PathwayBrowser/#/R-GGA-5340226 CYGB dioxygenates NO IEA Gallus gallus 58349 R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 58349 R-GGA-5419165 https://reactome.org/PathwayBrowser/#/R-GGA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Gallus gallus 58349 R-GGA-5423637 https://reactome.org/PathwayBrowser/#/R-GGA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Gallus gallus 58349 R-GGA-5423664 https://reactome.org/PathwayBrowser/#/R-GGA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Gallus gallus 58349 R-GGA-5423672 https://reactome.org/PathwayBrowser/#/R-GGA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Gallus gallus 58349 R-GGA-5423678 https://reactome.org/PathwayBrowser/#/R-GGA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Gallus gallus 58349 R-GGA-548818 https://reactome.org/PathwayBrowser/#/R-GGA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Gallus gallus 58349 R-GGA-548831 https://reactome.org/PathwayBrowser/#/R-GGA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Gallus gallus 58349 R-GGA-5652172 https://reactome.org/PathwayBrowser/#/R-GGA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Gallus gallus 58349 R-GGA-5661240 https://reactome.org/PathwayBrowser/#/R-GGA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Gallus gallus 58349 R-GGA-5661256 https://reactome.org/PathwayBrowser/#/R-GGA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Gallus gallus 58349 R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus 58349 R-GGA-5668718 https://reactome.org/PathwayBrowser/#/R-GGA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 58349 R-GGA-5668731 https://reactome.org/PathwayBrowser/#/R-GGA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 58349 R-GGA-5692232 https://reactome.org/PathwayBrowser/#/R-GGA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Gallus gallus 58349 R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus 58349 R-GGA-5693390 https://reactome.org/PathwayBrowser/#/R-GGA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Gallus gallus 58349 R-GGA-5696822 https://reactome.org/PathwayBrowser/#/R-GGA-5696822 AKR1B15 reduces EST17b to E1 IEA Gallus gallus 58349 R-GGA-6783955 https://reactome.org/PathwayBrowser/#/R-GGA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 58349 R-GGA-6786239 https://reactome.org/PathwayBrowser/#/R-GGA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Gallus gallus 58349 R-GGA-6787642 https://reactome.org/PathwayBrowser/#/R-GGA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Gallus gallus 58349 R-GGA-6789092 https://reactome.org/PathwayBrowser/#/R-GGA-6789092 NOX2 generates superoxide anion from oxygen IEA Gallus gallus 58349 R-GGA-6799722 https://reactome.org/PathwayBrowser/#/R-GGA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Gallus gallus 58349 R-GGA-6807053 https://reactome.org/PathwayBrowser/#/R-GGA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Gallus gallus 58349 R-GGA-6807055 https://reactome.org/PathwayBrowser/#/R-GGA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Gallus gallus 58349 R-GGA-6807064 https://reactome.org/PathwayBrowser/#/R-GGA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Gallus gallus 58349 R-GGA-6807557 https://reactome.org/PathwayBrowser/#/R-GGA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Gallus gallus 58349 R-GGA-6808487 https://reactome.org/PathwayBrowser/#/R-GGA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Gallus gallus 58349 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Gallus gallus 58349 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Gallus gallus 58349 R-GGA-70938 https://reactome.org/PathwayBrowser/#/R-GGA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Gallus gallus 58349 R-GGA-71200 https://reactome.org/PathwayBrowser/#/R-GGA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Gallus gallus 58349 R-GGA-71299 https://reactome.org/PathwayBrowser/#/R-GGA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Gallus gallus 58349 R-GGA-71682 https://reactome.org/PathwayBrowser/#/R-GGA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 58349 R-GGA-73585 https://reactome.org/PathwayBrowser/#/R-GGA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Gallus gallus 58349 R-GGA-73616 https://reactome.org/PathwayBrowser/#/R-GGA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Gallus gallus 58349 R-GGA-73646 https://reactome.org/PathwayBrowser/#/R-GGA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Gallus gallus 58349 R-GGA-74872 https://reactome.org/PathwayBrowser/#/R-GGA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Gallus gallus 58349 R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Gallus gallus 58349 R-GGA-75883 https://reactome.org/PathwayBrowser/#/R-GGA-75883 DHRS7B reduces GO3P to HXDG3P IEA Gallus gallus 58349 R-GGA-8862137 https://reactome.org/PathwayBrowser/#/R-GGA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Gallus gallus 58349 R-GGA-8865107 https://reactome.org/PathwayBrowser/#/R-GGA-8865107 MICAL1 produces NADP+, H2O2 IEA Gallus gallus 58349 R-GGA-8937419 https://reactome.org/PathwayBrowser/#/R-GGA-8937419 CBR3 reduces DOX to DOXOL IEA Gallus gallus 58349 R-GGA-8952873 https://reactome.org/PathwayBrowser/#/R-GGA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Gallus gallus 58349 R-GGA-8955030 https://reactome.org/PathwayBrowser/#/R-GGA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Gallus gallus 58349 R-GGA-9012036 https://reactome.org/PathwayBrowser/#/R-GGA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Gallus gallus 58349 R-GGA-9012349 https://reactome.org/PathwayBrowser/#/R-GGA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Gallus gallus 58349 R-GGA-9020255 https://reactome.org/PathwayBrowser/#/R-GGA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Gallus gallus 58349 R-GGA-9020256 https://reactome.org/PathwayBrowser/#/R-GGA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Gallus gallus 58349 R-GGA-9020277 https://reactome.org/PathwayBrowser/#/R-GGA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Gallus gallus 58349 R-GGA-9020278 https://reactome.org/PathwayBrowser/#/R-GGA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Gallus gallus 58349 R-GGA-9025995 https://reactome.org/PathwayBrowser/#/R-GGA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Gallus gallus 58349 R-GGA-9025999 https://reactome.org/PathwayBrowser/#/R-GGA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Gallus gallus 58349 R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus 58349 R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 58349 R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 58349 R-GGA-9037761 https://reactome.org/PathwayBrowser/#/R-GGA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Gallus gallus 58349 R-GGA-917811 https://reactome.org/PathwayBrowser/#/R-GGA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Gallus gallus 58349 R-GGA-9705713 https://reactome.org/PathwayBrowser/#/R-GGA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Gallus gallus 58349 R-GGA-9705714 https://reactome.org/PathwayBrowser/#/R-GGA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Gallus gallus 58349 R-GGA-9709098 https://reactome.org/PathwayBrowser/#/R-GGA-9709098 DHFR dimer reduces FOLA to DHF IEA Gallus gallus 58349 R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus 58349 R-GGA-9755937 https://reactome.org/PathwayBrowser/#/R-GGA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Gallus gallus 58349 R-GGA-9756138 https://reactome.org/PathwayBrowser/#/R-GGA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Gallus gallus 58349 R-GGA-9756162 https://reactome.org/PathwayBrowser/#/R-GGA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Gallus gallus 58349 R-GGA-9756169 https://reactome.org/PathwayBrowser/#/R-GGA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Gallus gallus 58349 R-GGA-9756180 https://reactome.org/PathwayBrowser/#/R-GGA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Gallus gallus 58349 R-GGA-975629 https://reactome.org/PathwayBrowser/#/R-GGA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Gallus gallus 58349 R-GGA-9757706 https://reactome.org/PathwayBrowser/#/R-GGA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Gallus gallus 58349 R-GGA-9759259 https://reactome.org/PathwayBrowser/#/R-GGA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Gallus gallus 58349 R-HSA-1222376 https://reactome.org/PathwayBrowser/#/R-HSA-1222376 NOX2 generates superoxide from oxygen TAS Homo sapiens 58349 R-HSA-1222399 https://reactome.org/PathwayBrowser/#/R-HSA-1222399 Iron is reduced and separates from mycobactin IEA Homo sapiens 58349 R-HSA-1222485 https://reactome.org/PathwayBrowser/#/R-HSA-1222485 TrxB reactivates TrxA TAS Homo sapiens 58349 R-HSA-1475414 https://reactome.org/PathwayBrowser/#/R-HSA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) TAS Homo sapiens 58349 R-HSA-1497794 https://reactome.org/PathwayBrowser/#/R-HSA-1497794 Salvage - BH2 is reduced to BH4 by DHFR IEA Homo sapiens 58349 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 58349 R-HSA-1497869 https://reactome.org/PathwayBrowser/#/R-HSA-1497869 Salvage - Sepiapterin is reduced to BH2 TAS Homo sapiens 58349 R-HSA-156526 https://reactome.org/PathwayBrowser/#/R-HSA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO TAS Homo sapiens 58349 R-HSA-1655453 https://reactome.org/PathwayBrowser/#/R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU TAS Homo sapiens 58349 R-HSA-189384 https://reactome.org/PathwayBrowser/#/R-HSA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL TAS Homo sapiens 58349 R-HSA-189398 https://reactome.org/PathwayBrowser/#/R-HSA-189398 HMOX1 dimer, HMOX2 cleave heme TAS Homo sapiens 58349 R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 58349 R-HSA-191352 https://reactome.org/PathwayBrowser/#/R-HSA-191352 HMGCR dimer reduces bHMG-CoA to MVA TAS Homo sapiens 58349 R-HSA-191402 https://reactome.org/PathwayBrowser/#/R-HSA-191402 Reduction of presqualene diphosphate to form squalene TAS Homo sapiens 58349 R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 58349 R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 58349 R-HSA-191999 https://reactome.org/PathwayBrowser/#/R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol TAS Homo sapiens 58349 R-HSA-192033 https://reactome.org/PathwayBrowser/#/R-HSA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one TAS Homo sapiens 58349 R-HSA-192036 https://reactome.org/PathwayBrowser/#/R-HSA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol TAS Homo sapiens 58349 R-HSA-192042 https://reactome.org/PathwayBrowser/#/R-HSA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 58349 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 58349 R-HSA-192054 https://reactome.org/PathwayBrowser/#/R-HSA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) TAS Homo sapiens 58349 R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 58349 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 58349 R-HSA-192067 https://reactome.org/PathwayBrowser/#/R-HSA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one TAS Homo sapiens 58349 R-HSA-192123 https://reactome.org/PathwayBrowser/#/R-HSA-192123 CYP27A1 27-hydroxylates CHOL TAS Homo sapiens 58349 R-HSA-192157 https://reactome.org/PathwayBrowser/#/R-HSA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE TAS Homo sapiens 58349 R-HSA-192160 https://reactome.org/PathwayBrowser/#/R-HSA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol TAS Homo sapiens 58349 R-HSA-192178 https://reactome.org/PathwayBrowser/#/R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL TAS Homo sapiens 58349 R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 58349 R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 58349 R-HSA-193064 https://reactome.org/PathwayBrowser/#/R-HSA-193064 HSD17B3-like proteins reducde ANDST to TEST TAS Homo sapiens 58349 R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 58349 R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 58349 R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 58349 R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 58349 R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 58349 R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 58349 R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 58349 R-HSA-193393 https://reactome.org/PathwayBrowser/#/R-HSA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol TAS Homo sapiens 58349 R-HSA-193460 https://reactome.org/PathwayBrowser/#/R-HSA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) TAS Homo sapiens 58349 R-HSA-193497 https://reactome.org/PathwayBrowser/#/R-HSA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al TAS Homo sapiens 58349 R-HSA-193709 https://reactome.org/PathwayBrowser/#/R-HSA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL TAS Homo sapiens 58349 R-HSA-193713 https://reactome.org/PathwayBrowser/#/R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) TAS Homo sapiens 58349 R-HSA-193719 https://reactome.org/PathwayBrowser/#/R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 58349 R-HSA-193737 https://reactome.org/PathwayBrowser/#/R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) TAS Homo sapiens 58349 R-HSA-193746 https://reactome.org/PathwayBrowser/#/R-HSA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one TAS Homo sapiens 58349 R-HSA-193755 https://reactome.org/PathwayBrowser/#/R-HSA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one TAS Homo sapiens 58349 R-HSA-193758 https://reactome.org/PathwayBrowser/#/R-HSA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol TAS Homo sapiens 58349 R-HSA-193780 https://reactome.org/PathwayBrowser/#/R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al TAS Homo sapiens 58349 R-HSA-193781 https://reactome.org/PathwayBrowser/#/R-HSA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol TAS Homo sapiens 58349 R-HSA-193787 https://reactome.org/PathwayBrowser/#/R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol TAS Homo sapiens 58349 R-HSA-193792 https://reactome.org/PathwayBrowser/#/R-HSA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 58349 R-HSA-193800 https://reactome.org/PathwayBrowser/#/R-HSA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol TAS Homo sapiens 58349 R-HSA-193821 https://reactome.org/PathwayBrowser/#/R-HSA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one TAS Homo sapiens 58349 R-HSA-193824 https://reactome.org/PathwayBrowser/#/R-HSA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one TAS Homo sapiens 58349 R-HSA-193841 https://reactome.org/PathwayBrowser/#/R-HSA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol TAS Homo sapiens 58349 R-HSA-193845 https://reactome.org/PathwayBrowser/#/R-HSA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE TAS Homo sapiens 58349 R-HSA-193964 https://reactome.org/PathwayBrowser/#/R-HSA-193964 CYP21A2 21-hydroxylates PROG TAS Homo sapiens 58349 R-HSA-193965 https://reactome.org/PathwayBrowser/#/R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO TAS Homo sapiens 58349 R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 58349 R-HSA-193995 https://reactome.org/PathwayBrowser/#/R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST TAS Homo sapiens 58349 R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 58349 R-HSA-194017 https://reactome.org/PathwayBrowser/#/R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST TAS Homo sapiens 58349 R-HSA-194023 https://reactome.org/PathwayBrowser/#/R-HSA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR TAS Homo sapiens 58349 R-HSA-194632 https://reactome.org/PathwayBrowser/#/R-HSA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) TAS Homo sapiens 58349 R-HSA-194641 https://reactome.org/PathwayBrowser/#/R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 58349 R-HSA-194669 https://reactome.org/PathwayBrowser/#/R-HSA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 58349 R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 58349 R-HSA-194689 https://reactome.org/PathwayBrowser/#/R-HSA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 58349 R-HSA-194698 https://reactome.org/PathwayBrowser/#/R-HSA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] TAS Homo sapiens 58349 R-HSA-195664 https://reactome.org/PathwayBrowser/#/R-HSA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol TAS Homo sapiens 58349 R-HSA-196060 https://reactome.org/PathwayBrowser/#/R-HSA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol TAS Homo sapiens 58349 R-HSA-196402 https://reactome.org/PathwayBrowser/#/R-HSA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol TAS Homo sapiens 58349 R-HSA-196417 https://reactome.org/PathwayBrowser/#/R-HSA-196417 Reduction of desmosterol to cholesterol TAS Homo sapiens 58349 R-HSA-197198 https://reactome.org/PathwayBrowser/#/R-HSA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ TAS Homo sapiens 58349 R-HSA-197963 https://reactome.org/PathwayBrowser/#/R-HSA-197963 DHFR2 reduces FOLA to DHF TAS Homo sapiens 58349 R-HSA-197972 https://reactome.org/PathwayBrowser/#/R-HSA-197972 DHF is reduced to tetrahydrofolate (THF) TAS Homo sapiens 58349 R-HSA-200644 https://reactome.org/PathwayBrowser/#/R-HSA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ TAS Homo sapiens 58349 R-HSA-200676 https://reactome.org/PathwayBrowser/#/R-HSA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG TAS Homo sapiens 58349 R-HSA-200718 https://reactome.org/PathwayBrowser/#/R-HSA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG TAS Homo sapiens 58349 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 58349 R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 58349 R-HSA-209772 https://reactome.org/PathwayBrowser/#/R-HSA-209772 Thyroxine is deiodinated to triiodothyronine TAS Homo sapiens 58349 R-HSA-209845 https://reactome.org/PathwayBrowser/#/R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D TAS Homo sapiens 58349 R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 58349 R-HSA-211873 https://reactome.org/PathwayBrowser/#/R-HSA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 TAS Homo sapiens 58349 R-HSA-211923 https://reactome.org/PathwayBrowser/#/R-HSA-211923 CYP26C1 4-hydroxylates 9cRA TAS Homo sapiens 58349 R-HSA-211950 https://reactome.org/PathwayBrowser/#/R-HSA-211950 CYP24A1 24-hydroxylates CTL TAS Homo sapiens 58349 R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 58349 R-HSA-2161549 https://reactome.org/PathwayBrowser/#/R-HSA-2161549 PGH2 is reduced to PGF2a by AKR1C3 TAS Homo sapiens 58349 R-HSA-2161567 https://reactome.org/PathwayBrowser/#/R-HSA-2161567 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 IEA Homo sapiens 58349 R-HSA-2161614 https://reactome.org/PathwayBrowser/#/R-HSA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 TAS Homo sapiens 58349 R-HSA-2161651 https://reactome.org/PathwayBrowser/#/R-HSA-2161651 PGE2 is converted to PGF2a by CBR1 TAS Homo sapiens 58349 R-HSA-2161692 https://reactome.org/PathwayBrowser/#/R-HSA-2161692 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1 IEA Homo sapiens 58349 R-HSA-2161745 https://reactome.org/PathwayBrowser/#/R-HSA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 TAS Homo sapiens 58349 R-HSA-2161776 https://reactome.org/PathwayBrowser/#/R-HSA-2161776 5S-HETE is oxidised to 5-oxoETE by 5-HEDH TAS Homo sapiens 58349 R-HSA-2161789 https://reactome.org/PathwayBrowser/#/R-HSA-2161789 15S-HETE is oxidised to 15-oxoETE by 15-HEDH TAS Homo sapiens 58349 R-HSA-2161792 https://reactome.org/PathwayBrowser/#/R-HSA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 TAS Homo sapiens 58349 R-HSA-2161844 https://reactome.org/PathwayBrowser/#/R-HSA-2161844 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 IEA Homo sapiens 58349 R-HSA-2161890 https://reactome.org/PathwayBrowser/#/R-HSA-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) TAS Homo sapiens 58349 R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) TAS Homo sapiens 58349 R-HSA-2161951 https://reactome.org/PathwayBrowser/#/R-HSA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 TAS Homo sapiens 58349 R-HSA-2161979 https://reactome.org/PathwayBrowser/#/R-HSA-2161979 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH TAS Homo sapiens 58349 R-HSA-2162191 https://reactome.org/PathwayBrowser/#/R-HSA-2162191 Unknown enzyme hydroxylates DMPhOH IEA Homo sapiens 58349 R-HSA-2395517 https://reactome.org/PathwayBrowser/#/R-HSA-2395517 NADPH transfers electrons to FDXR TAS Homo sapiens 58349 R-HSA-2408542 https://reactome.org/PathwayBrowser/#/R-HSA-2408542 GSSeSG is reduced to GSSeH and GSH by GSR IEA Homo sapiens 58349 R-HSA-2408548 https://reactome.org/PathwayBrowser/#/R-HSA-2408548 PAPSe is reduced to SeO3(2-) by PAPSe reductase IEA Homo sapiens 58349 R-HSA-2408558 https://reactome.org/PathwayBrowser/#/R-HSA-2408558 SeO3(2-) is reduced to H2Se by TXNRD1 IEA Homo sapiens 58349 R-HSA-2464803 https://reactome.org/PathwayBrowser/#/R-HSA-2464803 RDH8 reduces atRAL to atROL IEA Homo sapiens 58349 R-HSA-2464822 https://reactome.org/PathwayBrowser/#/R-HSA-2464822 RDH12 reduces atRAL to atROL TAS Homo sapiens 58349 R-HSA-2465921 https://reactome.org/PathwayBrowser/#/R-HSA-2465921 11cRDH oxidises 11cROL to 11cRAL TAS Homo sapiens 58349 R-HSA-2465940 https://reactome.org/PathwayBrowser/#/R-HSA-2465940 atRAL is reduced to atROL TAS Homo sapiens 58349 R-HSA-2564824 https://reactome.org/PathwayBrowser/#/R-HSA-2564824 NADPH reduces NDOR1:CIAPIN1 IEA Homo sapiens 58349 R-HSA-2855252 https://reactome.org/PathwayBrowser/#/R-HSA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL TAS Homo sapiens 58349 R-HSA-3149518 https://reactome.org/PathwayBrowser/#/R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl TAS Homo sapiens 58349 R-HSA-3149519 https://reactome.org/PathwayBrowser/#/R-HSA-3149519 MMACHC decyanates CNCbl TAS Homo sapiens 58349 R-HSA-3323050 https://reactome.org/PathwayBrowser/#/R-HSA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH TAS Homo sapiens 58349 R-HSA-3323079 https://reactome.org/PathwayBrowser/#/R-HSA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 58349 R-HSA-350869 https://reactome.org/PathwayBrowser/#/R-HSA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) TAS Homo sapiens 58349 R-HSA-389540 https://reactome.org/PathwayBrowser/#/R-HSA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 58349 R-HSA-390425 https://reactome.org/PathwayBrowser/#/R-HSA-390425 FAR1 reduces PalmCoA to HXOL TAS Homo sapiens 58349 R-HSA-390438 https://reactome.org/PathwayBrowser/#/R-HSA-390438 FAR2 reduces PalmCoA to HXOL TAS Homo sapiens 58349 R-HSA-418436 https://reactome.org/PathwayBrowser/#/R-HSA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) TAS Homo sapiens 58349 R-HSA-428123 https://reactome.org/PathwayBrowser/#/R-HSA-428123 KDSR reduces 3-ketosphingoid TAS Homo sapiens 58349 R-HSA-4419979 https://reactome.org/PathwayBrowser/#/R-HSA-4419979 SRD5A3 reduces pPNOL to DCHOL TAS Homo sapiens 58349 R-HSA-450971 https://reactome.org/PathwayBrowser/#/R-HSA-450971 NNT dimer transfers proton from NADPH to NAD+ TAS Homo sapiens 58349 R-HSA-450984 https://reactome.org/PathwayBrowser/#/R-HSA-450984 IDH2 dimer decarboxylates isocitrate TAS Homo sapiens 58349 R-HSA-469659 https://reactome.org/PathwayBrowser/#/R-HSA-469659 SRD5A1 dehydrogenates TEST to DHTEST TAS Homo sapiens 58349 R-HSA-508040 https://reactome.org/PathwayBrowser/#/R-HSA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] TAS Homo sapiens 58349 R-HSA-514604 https://reactome.org/PathwayBrowser/#/R-HSA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) TAS Homo sapiens 58349 R-HSA-5218841 https://reactome.org/PathwayBrowser/#/R-HSA-5218841 NADPH oxidase 2 generates superoxide from oxygen TAS Homo sapiens 58349 R-HSA-5263614 https://reactome.org/PathwayBrowser/#/R-HSA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 TAS Homo sapiens 58349 R-HSA-5263616 https://reactome.org/PathwayBrowser/#/R-HSA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 TAS Homo sapiens 58349 R-HSA-5340226 https://reactome.org/PathwayBrowser/#/R-HSA-5340226 CYGB dioxygenates NO TAS Homo sapiens 58349 R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 58349 R-HSA-5419165 https://reactome.org/PathwayBrowser/#/R-HSA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL TAS Homo sapiens 58349 R-HSA-5423637 https://reactome.org/PathwayBrowser/#/R-HSA-5423637 AKR dimers reduce AFBDHO to AFBDOH TAS Homo sapiens 58349 R-HSA-5423647 https://reactome.org/PathwayBrowser/#/R-HSA-5423647 CYP2A13 oxidises AFM1 to AFM1E TAS Homo sapiens 58349 R-HSA-5423664 https://reactome.org/PathwayBrowser/#/R-HSA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 TAS Homo sapiens 58349 R-HSA-5423672 https://reactome.org/PathwayBrowser/#/R-HSA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO TAS Homo sapiens 58349 R-HSA-5423678 https://reactome.org/PathwayBrowser/#/R-HSA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 TAS Homo sapiens 58349 R-HSA-548818 https://reactome.org/PathwayBrowser/#/R-HSA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA TAS Homo sapiens 58349 R-HSA-548831 https://reactome.org/PathwayBrowser/#/R-HSA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA TAS Homo sapiens 58349 R-HSA-5602295 https://reactome.org/PathwayBrowser/#/R-HSA-5602295 CYP4F22 20-hydroxylates TrXA3 TAS Homo sapiens 58349 R-HSA-5615668 https://reactome.org/PathwayBrowser/#/R-HSA-5615668 AKR1C3 reduces atRAL to atROL TAS Homo sapiens 58349 R-HSA-5652172 https://reactome.org/PathwayBrowser/#/R-HSA-5652172 AKR1B1 reduces Glc to D-sorbitol TAS Homo sapiens 58349 R-HSA-5661240 https://reactome.org/PathwayBrowser/#/R-HSA-5661240 DCXR tetramer reduces L-xylulose to xylitol TAS Homo sapiens 58349 R-HSA-5661256 https://reactome.org/PathwayBrowser/#/R-HSA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate TAS Homo sapiens 58349 R-HSA-5668629 https://reactome.org/PathwayBrowser/#/R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP TAS Homo sapiens 58349 R-HSA-5668718 https://reactome.org/PathwayBrowser/#/R-HSA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 58349 R-HSA-5668731 https://reactome.org/PathwayBrowser/#/R-HSA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 58349 R-HSA-5692232 https://reactome.org/PathwayBrowser/#/R-HSA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione TAS Homo sapiens 58349 R-HSA-5692283 https://reactome.org/PathwayBrowser/#/R-HSA-5692283 ALD3A1 oxidises 4HPCP to CXPA TAS Homo sapiens 58349 R-HSA-5693390 https://reactome.org/PathwayBrowser/#/R-HSA-5693390 HSD17B11 dehydrogenates EST17b to E1 TAS Homo sapiens 58349 R-HSA-5696822 https://reactome.org/PathwayBrowser/#/R-HSA-5696822 AKR1B15 reduces EST17b to E1 TAS Homo sapiens 58349 R-HSA-6782296 https://reactome.org/PathwayBrowser/#/R-HSA-6782296 DUS2:EPRS reduces uridine to dihydrouridine in tRNAs IEA Homo sapiens 58349 R-HSA-6783955 https://reactome.org/PathwayBrowser/#/R-HSA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 58349 R-HSA-6786239 https://reactome.org/PathwayBrowser/#/R-HSA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE TAS Homo sapiens 58349 R-HSA-6787642 https://reactome.org/PathwayBrowser/#/R-HSA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc TAS Homo sapiens 58349 R-HSA-6789092 https://reactome.org/PathwayBrowser/#/R-HSA-6789092 NOX2 generates superoxide anion from oxygen TAS Homo sapiens 58349 R-HSA-6799722 https://reactome.org/PathwayBrowser/#/R-HSA-6799722 TP53I3 oxidoreductase generates unstable semiquinones TAS Homo sapiens 58349 R-HSA-6807053 https://reactome.org/PathwayBrowser/#/R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL TAS Homo sapiens 58349 R-HSA-6807055 https://reactome.org/PathwayBrowser/#/R-HSA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL TAS Homo sapiens 58349 R-HSA-6807064 https://reactome.org/PathwayBrowser/#/R-HSA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL TAS Homo sapiens 58349 R-HSA-6807557 https://reactome.org/PathwayBrowser/#/R-HSA-6807557 NOX4, NOX5 reduce O2 to O2.- TAS Homo sapiens 58349 R-HSA-6808487 https://reactome.org/PathwayBrowser/#/R-HSA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 58349 R-HSA-6808496 https://reactome.org/PathwayBrowser/#/R-HSA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 58349 R-HSA-6810594 https://reactome.org/PathwayBrowser/#/R-HSA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 58349 R-HSA-70377 https://reactome.org/PathwayBrowser/#/R-HSA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ TAS Homo sapiens 58349 R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] TAS Homo sapiens 58349 R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] TAS Homo sapiens 58349 R-HSA-70938 https://reactome.org/PathwayBrowser/#/R-HSA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O TAS Homo sapiens 58349 R-HSA-71200 https://reactome.org/PathwayBrowser/#/R-HSA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O TAS Homo sapiens 58349 R-HSA-71299 https://reactome.org/PathwayBrowser/#/R-HSA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ TAS Homo sapiens 58349 R-HSA-71682 https://reactome.org/PathwayBrowser/#/R-HSA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 58349 R-HSA-73585 https://reactome.org/PathwayBrowser/#/R-HSA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ TAS Homo sapiens 58349 R-HSA-73616 https://reactome.org/PathwayBrowser/#/R-HSA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ TAS Homo sapiens 58349 R-HSA-73646 https://reactome.org/PathwayBrowser/#/R-HSA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ TAS Homo sapiens 58349 R-HSA-74872 https://reactome.org/PathwayBrowser/#/R-HSA-74872 RDH10,11 oxidise 11cROL to 11cRAL TAS Homo sapiens 58349 R-HSA-75872 https://reactome.org/PathwayBrowser/#/R-HSA-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O TAS Homo sapiens 58349 R-HSA-75883 https://reactome.org/PathwayBrowser/#/R-HSA-75883 DHRS7B reduces GO3P to HXDG3P TAS Homo sapiens 58349 R-HSA-76494 https://reactome.org/PathwayBrowser/#/R-HSA-76494 POR reduces CYP450:Fe3+ to CYP450:Fe2+ TAS Homo sapiens 58349 R-HSA-804969 https://reactome.org/PathwayBrowser/#/R-HSA-804969 HSD17B1 hydrogenates E1 to EST17b TAS Homo sapiens 58349 R-HSA-880053 https://reactome.org/PathwayBrowser/#/R-HSA-880053 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] TAS Homo sapiens 58349 R-HSA-8862137 https://reactome.org/PathwayBrowser/#/R-HSA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 58349 R-HSA-8862152 https://reactome.org/PathwayBrowser/#/R-HSA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP TAS Homo sapiens 58349 R-HSA-8865107 https://reactome.org/PathwayBrowser/#/R-HSA-8865107 MICAL1 produces NADP+, H2O2 TAS Homo sapiens 58349 R-HSA-8937419 https://reactome.org/PathwayBrowser/#/R-HSA-8937419 CBR3 reduces DOX to DOXOL TAS Homo sapiens 58349 R-HSA-8952873 https://reactome.org/PathwayBrowser/#/R-HSA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA TAS Homo sapiens 58349 R-HSA-8955030 https://reactome.org/PathwayBrowser/#/R-HSA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ TAS Homo sapiens 58349 R-HSA-9012036 https://reactome.org/PathwayBrowser/#/R-HSA-9012036 ME1 tetramer decarboxylates MAL to PYR TAS Homo sapiens 58349 R-HSA-9012349 https://reactome.org/PathwayBrowser/#/R-HSA-9012349 ME3 tetramer decarboxylates MAL to PYR TAS Homo sapiens 58349 R-HSA-9018867 https://reactome.org/PathwayBrowser/#/R-HSA-9018867 5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2 TAS Homo sapiens 58349 R-HSA-9018874 https://reactome.org/PathwayBrowser/#/R-HSA-9018874 CYP monooxygenates EPA to 18(S)-HpEPE TAS Homo sapiens 58349 R-HSA-9018901 https://reactome.org/PathwayBrowser/#/R-HSA-9018901 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HpEPE to 18(R)-RvE2 TAS Homo sapiens 58349 R-HSA-9020255 https://reactome.org/PathwayBrowser/#/R-HSA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA TAS Homo sapiens 58349 R-HSA-9020256 https://reactome.org/PathwayBrowser/#/R-HSA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA TAS Homo sapiens 58349 R-HSA-9020262 https://reactome.org/PathwayBrowser/#/R-HSA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA TAS Homo sapiens 58349 R-HSA-9020277 https://reactome.org/PathwayBrowser/#/R-HSA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA TAS Homo sapiens 58349 R-HSA-9020278 https://reactome.org/PathwayBrowser/#/R-HSA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA TAS Homo sapiens 58349 R-HSA-9024881 https://reactome.org/PathwayBrowser/#/R-HSA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA TAS Homo sapiens 58349 R-HSA-9024983 https://reactome.org/PathwayBrowser/#/R-HSA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA TAS Homo sapiens 58349 R-HSA-9025995 https://reactome.org/PathwayBrowser/#/R-HSA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 TAS Homo sapiens 58349 R-HSA-9025999 https://reactome.org/PathwayBrowser/#/R-HSA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 TAS Homo sapiens 58349 R-HSA-9026007 https://reactome.org/PathwayBrowser/#/R-HSA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 TAS Homo sapiens 58349 R-HSA-9026917 https://reactome.org/PathwayBrowser/#/R-HSA-9026917 Lipoxygenase dehydrogenates 7(S),17(S)-diHp-DHA to 7S(8)-epoxy-17(S)-HDHA TAS Homo sapiens 58349 R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 58349 R-HSA-9027043 https://reactome.org/PathwayBrowser/#/R-HSA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA TAS Homo sapiens 58349 R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 58349 R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 58349 R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 58349 R-HSA-9027531 https://reactome.org/PathwayBrowser/#/R-HSA-9027531 Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA TAS Homo sapiens 58349 R-HSA-9027562 https://reactome.org/PathwayBrowser/#/R-HSA-9027562 Dehydrogenase dehydrogenates 17-HDHA to 17-oxo-DHA TAS Homo sapiens 58349 R-HSA-9027598 https://reactome.org/PathwayBrowser/#/R-HSA-9027598 Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3 TAS Homo sapiens 58349 R-HSA-9027600 https://reactome.org/PathwayBrowser/#/R-HSA-9027600 Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3 TAS Homo sapiens 58349 R-HSA-9027625 https://reactome.org/PathwayBrowser/#/R-HSA-9027625 5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3 TAS Homo sapiens 58349 R-HSA-9027631 https://reactome.org/PathwayBrowser/#/R-HSA-9027631 5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA TAS Homo sapiens 58349 R-HSA-9027632 https://reactome.org/PathwayBrowser/#/R-HSA-9027632 5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA TAS Homo sapiens 58349 R-HSA-9037761 https://reactome.org/PathwayBrowser/#/R-HSA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 TAS Homo sapiens 58349 R-HSA-917811 https://reactome.org/PathwayBrowser/#/R-HSA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ TAS Homo sapiens 58349 R-HSA-9673797 https://reactome.org/PathwayBrowser/#/R-HSA-9673797 NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 58349 R-HSA-9698758 https://reactome.org/PathwayBrowser/#/R-HSA-9698758 FLT3 ITD- and NOX4-dependent H2O2 production TAS Homo sapiens 58349 R-HSA-9705713 https://reactome.org/PathwayBrowser/#/R-HSA-9705713 SRD5A2 dehydrogenates TEST to DHTEST TAS Homo sapiens 58349 R-HSA-9705714 https://reactome.org/PathwayBrowser/#/R-HSA-9705714 SRD5A3 dehydrogenates TEST to DHTEST TAS Homo sapiens 58349 R-HSA-9709098 https://reactome.org/PathwayBrowser/#/R-HSA-9709098 DHFR dimer reduces FOLA to DHF TAS Homo sapiens 58349 R-HSA-9753285 https://reactome.org/PathwayBrowser/#/R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI TAS Homo sapiens 58349 R-HSA-9755937 https://reactome.org/PathwayBrowser/#/R-HSA-9755937 DHCR24 reduces LAN to 24,25-dhLAN TAS Homo sapiens 58349 R-HSA-9756138 https://reactome.org/PathwayBrowser/#/R-HSA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL TAS Homo sapiens 58349 R-HSA-9756162 https://reactome.org/PathwayBrowser/#/R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV TAS Homo sapiens 58349 R-HSA-9756169 https://reactome.org/PathwayBrowser/#/R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV TAS Homo sapiens 58349 R-HSA-9756180 https://reactome.org/PathwayBrowser/#/R-HSA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL TAS Homo sapiens 58349 R-HSA-975629 https://reactome.org/PathwayBrowser/#/R-HSA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL TAS Homo sapiens 58349 R-HSA-9757706 https://reactome.org/PathwayBrowser/#/R-HSA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell TAS Homo sapiens 58349 R-HSA-9758682 https://reactome.org/PathwayBrowser/#/R-HSA-9758682 AKR1C1 hydrogenates PREDN,PREDL TAS Homo sapiens 58349 R-HSA-9759259 https://reactome.org/PathwayBrowser/#/R-HSA-9759259 HSD11B2 dehydrogenates PREDL to PREDN TAS Homo sapiens 58349 R-HSA-9761849 https://reactome.org/PathwayBrowser/#/R-HSA-9761849 AcK-NFE2L2-dependent P6GD gene expression TAS Homo sapiens 58349 R-MMU-1222376 https://reactome.org/PathwayBrowser/#/R-MMU-1222376 NOX2 generates superoxide from oxygen IEA Mus musculus 58349 R-MMU-1475414 https://reactome.org/PathwayBrowser/#/R-MMU-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Mus musculus 58349 R-MMU-1497770 https://reactome.org/PathwayBrowser/#/R-MMU-1497770 Salvage - BH2 is reduced to BH4 by Dhfr TAS Mus musculus 58349 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 58349 R-MMU-1497869 https://reactome.org/PathwayBrowser/#/R-MMU-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Mus musculus 58349 R-MMU-156526 https://reactome.org/PathwayBrowser/#/R-MMU-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Mus musculus 58349 R-MMU-1655453 https://reactome.org/PathwayBrowser/#/R-MMU-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Mus musculus 58349 R-MMU-189384 https://reactome.org/PathwayBrowser/#/R-MMU-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Mus musculus 58349 R-MMU-189398 https://reactome.org/PathwayBrowser/#/R-MMU-189398 HMOX1 dimer, HMOX2 cleave heme IEA Mus musculus 58349 R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 58349 R-MMU-191352 https://reactome.org/PathwayBrowser/#/R-MMU-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Mus musculus 58349 R-MMU-191402 https://reactome.org/PathwayBrowser/#/R-MMU-191402 Reduction of presqualene diphosphate to form squalene IEA Mus musculus 58349 R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 58349 R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 58349 R-MMU-191999 https://reactome.org/PathwayBrowser/#/R-MMU-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Mus musculus 58349 R-MMU-192033 https://reactome.org/PathwayBrowser/#/R-MMU-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Mus musculus 58349 R-MMU-192036 https://reactome.org/PathwayBrowser/#/R-MMU-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Mus musculus 58349 R-MMU-192042 https://reactome.org/PathwayBrowser/#/R-MMU-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 58349 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 58349 R-MMU-192054 https://reactome.org/PathwayBrowser/#/R-MMU-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Mus musculus 58349 R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 58349 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 58349 R-MMU-192067 https://reactome.org/PathwayBrowser/#/R-MMU-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Mus musculus 58349 R-MMU-192123 https://reactome.org/PathwayBrowser/#/R-MMU-192123 CYP27A1 27-hydroxylates CHOL IEA Mus musculus 58349 R-MMU-192157 https://reactome.org/PathwayBrowser/#/R-MMU-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Mus musculus 58349 R-MMU-192160 https://reactome.org/PathwayBrowser/#/R-MMU-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Mus musculus 58349 R-MMU-192178 https://reactome.org/PathwayBrowser/#/R-MMU-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Mus musculus 58349 R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 58349 R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 58349 R-MMU-193064 https://reactome.org/PathwayBrowser/#/R-MMU-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Mus musculus 58349 R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 58349 R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 58349 R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 58349 R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 58349 R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 58349 R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 58349 R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 58349 R-MMU-193393 https://reactome.org/PathwayBrowser/#/R-MMU-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Mus musculus 58349 R-MMU-193460 https://reactome.org/PathwayBrowser/#/R-MMU-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Mus musculus 58349 R-MMU-193497 https://reactome.org/PathwayBrowser/#/R-MMU-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Mus musculus 58349 R-MMU-193709 https://reactome.org/PathwayBrowser/#/R-MMU-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Mus musculus 58349 R-MMU-193713 https://reactome.org/PathwayBrowser/#/R-MMU-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Mus musculus 58349 R-MMU-193719 https://reactome.org/PathwayBrowser/#/R-MMU-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 58349 R-MMU-193737 https://reactome.org/PathwayBrowser/#/R-MMU-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Mus musculus 58349 R-MMU-193746 https://reactome.org/PathwayBrowser/#/R-MMU-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Mus musculus 58349 R-MMU-193755 https://reactome.org/PathwayBrowser/#/R-MMU-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Mus musculus 58349 R-MMU-193758 https://reactome.org/PathwayBrowser/#/R-MMU-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Mus musculus 58349 R-MMU-193780 https://reactome.org/PathwayBrowser/#/R-MMU-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Mus musculus 58349 R-MMU-193781 https://reactome.org/PathwayBrowser/#/R-MMU-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Mus musculus 58349 R-MMU-193787 https://reactome.org/PathwayBrowser/#/R-MMU-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Mus musculus 58349 R-MMU-193792 https://reactome.org/PathwayBrowser/#/R-MMU-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Mus musculus 58349 R-MMU-193800 https://reactome.org/PathwayBrowser/#/R-MMU-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Mus musculus 58349 R-MMU-193821 https://reactome.org/PathwayBrowser/#/R-MMU-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Mus musculus 58349 R-MMU-193824 https://reactome.org/PathwayBrowser/#/R-MMU-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Mus musculus 58349 R-MMU-193841 https://reactome.org/PathwayBrowser/#/R-MMU-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Mus musculus 58349 R-MMU-193845 https://reactome.org/PathwayBrowser/#/R-MMU-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Mus musculus 58349 R-MMU-193964 https://reactome.org/PathwayBrowser/#/R-MMU-193964 CYP21A2 21-hydroxylates PROG IEA Mus musculus 58349 R-MMU-193965 https://reactome.org/PathwayBrowser/#/R-MMU-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Mus musculus 58349 R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 58349 R-MMU-193995 https://reactome.org/PathwayBrowser/#/R-MMU-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Mus musculus 58349 R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 58349 R-MMU-194017 https://reactome.org/PathwayBrowser/#/R-MMU-194017 CYP11B2 oxidises 11DCORST to CORST IEA Mus musculus 58349 R-MMU-194023 https://reactome.org/PathwayBrowser/#/R-MMU-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Mus musculus 58349 R-MMU-194632 https://reactome.org/PathwayBrowser/#/R-MMU-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Mus musculus 58349 R-MMU-194641 https://reactome.org/PathwayBrowser/#/R-MMU-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 58349 R-MMU-194669 https://reactome.org/PathwayBrowser/#/R-MMU-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 58349 R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 58349 R-MMU-194689 https://reactome.org/PathwayBrowser/#/R-MMU-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Mus musculus 58349 R-MMU-194698 https://reactome.org/PathwayBrowser/#/R-MMU-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Mus musculus 58349 R-MMU-195664 https://reactome.org/PathwayBrowser/#/R-MMU-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Mus musculus 58349 R-MMU-196060 https://reactome.org/PathwayBrowser/#/R-MMU-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Mus musculus 58349 R-MMU-196402 https://reactome.org/PathwayBrowser/#/R-MMU-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Mus musculus 58349 R-MMU-196417 https://reactome.org/PathwayBrowser/#/R-MMU-196417 Reduction of desmosterol to cholesterol IEA Mus musculus 58349 R-MMU-197198 https://reactome.org/PathwayBrowser/#/R-MMU-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Mus musculus 58349 R-MMU-197963 https://reactome.org/PathwayBrowser/#/R-MMU-197963 DHFR2 reduces FOLA to DHF IEA Mus musculus 58349 R-MMU-197972 https://reactome.org/PathwayBrowser/#/R-MMU-197972 DHF is reduced to tetrahydrofolate (THF) IEA Mus musculus 58349 R-MMU-200644 https://reactome.org/PathwayBrowser/#/R-MMU-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Mus musculus 58349 R-MMU-200676 https://reactome.org/PathwayBrowser/#/R-MMU-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Mus musculus 58349 R-MMU-200718 https://reactome.org/PathwayBrowser/#/R-MMU-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Mus musculus 58349 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 58349 R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 58349 R-MMU-209772 https://reactome.org/PathwayBrowser/#/R-MMU-209772 Thyroxine is deiodinated to triiodothyronine IEA Mus musculus 58349 R-MMU-209845 https://reactome.org/PathwayBrowser/#/R-MMU-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Mus musculus 58349 R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 58349 R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus 58349 R-MMU-211923 https://reactome.org/PathwayBrowser/#/R-MMU-211923 CYP26C1 4-hydroxylates 9cRA IEA Mus musculus 58349 R-MMU-211950 https://reactome.org/PathwayBrowser/#/R-MMU-211950 CYP24A1 24-hydroxylates CTL IEA Mus musculus 58349 R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 58349 R-MMU-2161549 https://reactome.org/PathwayBrowser/#/R-MMU-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Mus musculus 58349 R-MMU-2161614 https://reactome.org/PathwayBrowser/#/R-MMU-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Mus musculus 58349 R-MMU-2161638 https://reactome.org/PathwayBrowser/#/R-MMU-2161638 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by Ptgr2 TAS Mus musculus 58349 R-MMU-2161651 https://reactome.org/PathwayBrowser/#/R-MMU-2161651 PGE2 is converted to PGF2a by CBR1 IEA Mus musculus 58349 R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus 58349 R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus 58349 R-MMU-2161890 https://reactome.org/PathwayBrowser/#/R-MMU-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Mus musculus 58349 R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Mus musculus 58349 R-MMU-2161951 https://reactome.org/PathwayBrowser/#/R-MMU-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Mus musculus 58349 R-MMU-2395517 https://reactome.org/PathwayBrowser/#/R-MMU-2395517 NADPH transfers electrons to FDXR IEA Mus musculus 58349 R-MMU-2464822 https://reactome.org/PathwayBrowser/#/R-MMU-2464822 RDH12 reduces atRAL to atROL IEA Mus musculus 58349 R-MMU-2465940 https://reactome.org/PathwayBrowser/#/R-MMU-2465940 atRAL is reduced to atROL IEA Mus musculus 58349 R-MMU-2855252 https://reactome.org/PathwayBrowser/#/R-MMU-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Mus musculus 58349 R-MMU-3149518 https://reactome.org/PathwayBrowser/#/R-MMU-3149518 MTRR reduces cob(II)alamin to meCbl IEA Mus musculus 58349 R-MMU-3149519 https://reactome.org/PathwayBrowser/#/R-MMU-3149519 MMACHC decyanates CNCbl IEA Mus musculus 58349 R-MMU-3323050 https://reactome.org/PathwayBrowser/#/R-MMU-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Mus musculus 58349 R-MMU-3323079 https://reactome.org/PathwayBrowser/#/R-MMU-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 58349 R-MMU-350869 https://reactome.org/PathwayBrowser/#/R-MMU-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Mus musculus 58349 R-MMU-389540 https://reactome.org/PathwayBrowser/#/R-MMU-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 58349 R-MMU-390425 https://reactome.org/PathwayBrowser/#/R-MMU-390425 FAR1 reduces PalmCoA to HXOL IEA Mus musculus 58349 R-MMU-390438 https://reactome.org/PathwayBrowser/#/R-MMU-390438 FAR2 reduces PalmCoA to HXOL IEA Mus musculus 58349 R-MMU-418436 https://reactome.org/PathwayBrowser/#/R-MMU-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Mus musculus 58349 R-MMU-428123 https://reactome.org/PathwayBrowser/#/R-MMU-428123 KDSR reduces 3-ketosphingoid IEA Mus musculus 58349 R-MMU-4419979 https://reactome.org/PathwayBrowser/#/R-MMU-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Mus musculus 58349 R-MMU-450971 https://reactome.org/PathwayBrowser/#/R-MMU-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Mus musculus 58349 R-MMU-450984 https://reactome.org/PathwayBrowser/#/R-MMU-450984 IDH2 dimer decarboxylates isocitrate IEA Mus musculus 58349 R-MMU-469659 https://reactome.org/PathwayBrowser/#/R-MMU-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Mus musculus 58349 R-MMU-508040 https://reactome.org/PathwayBrowser/#/R-MMU-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Mus musculus 58349 R-MMU-514604 https://reactome.org/PathwayBrowser/#/R-MMU-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Mus musculus 58349 R-MMU-5218841 https://reactome.org/PathwayBrowser/#/R-MMU-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Mus musculus 58349 R-MMU-5263614 https://reactome.org/PathwayBrowser/#/R-MMU-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Mus musculus 58349 R-MMU-5263616 https://reactome.org/PathwayBrowser/#/R-MMU-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Mus musculus 58349 R-MMU-5340226 https://reactome.org/PathwayBrowser/#/R-MMU-5340226 CYGB dioxygenates NO IEA Mus musculus 58349 R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 58349 R-MMU-5419165 https://reactome.org/PathwayBrowser/#/R-MMU-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Mus musculus 58349 R-MMU-5423637 https://reactome.org/PathwayBrowser/#/R-MMU-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Mus musculus 58349 R-MMU-5423647 https://reactome.org/PathwayBrowser/#/R-MMU-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Mus musculus 58349 R-MMU-5423664 https://reactome.org/PathwayBrowser/#/R-MMU-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Mus musculus 58349 R-MMU-5423672 https://reactome.org/PathwayBrowser/#/R-MMU-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Mus musculus 58349 R-MMU-5423678 https://reactome.org/PathwayBrowser/#/R-MMU-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Mus musculus 58349 R-MMU-548818 https://reactome.org/PathwayBrowser/#/R-MMU-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Mus musculus 58349 R-MMU-548831 https://reactome.org/PathwayBrowser/#/R-MMU-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Mus musculus 58349 R-MMU-5602295 https://reactome.org/PathwayBrowser/#/R-MMU-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Mus musculus 58349 R-MMU-5615668 https://reactome.org/PathwayBrowser/#/R-MMU-5615668 AKR1C3 reduces atRAL to atROL IEA Mus musculus 58349 R-MMU-5652172 https://reactome.org/PathwayBrowser/#/R-MMU-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Mus musculus 58349 R-MMU-5661240 https://reactome.org/PathwayBrowser/#/R-MMU-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Mus musculus 58349 R-MMU-5661256 https://reactome.org/PathwayBrowser/#/R-MMU-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Mus musculus 58349 R-MMU-5668629 https://reactome.org/PathwayBrowser/#/R-MMU-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Mus musculus 58349 R-MMU-5668718 https://reactome.org/PathwayBrowser/#/R-MMU-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 58349 R-MMU-5668731 https://reactome.org/PathwayBrowser/#/R-MMU-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 58349 R-MMU-5692232 https://reactome.org/PathwayBrowser/#/R-MMU-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Mus musculus 58349 R-MMU-5692283 https://reactome.org/PathwayBrowser/#/R-MMU-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Mus musculus 58349 R-MMU-5693390 https://reactome.org/PathwayBrowser/#/R-MMU-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Mus musculus 58349 R-MMU-5696822 https://reactome.org/PathwayBrowser/#/R-MMU-5696822 AKR1B15 reduces EST17b to E1 IEA Mus musculus 58349 R-MMU-6783955 https://reactome.org/PathwayBrowser/#/R-MMU-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 58349 R-MMU-6786239 https://reactome.org/PathwayBrowser/#/R-MMU-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Mus musculus 58349 R-MMU-6787642 https://reactome.org/PathwayBrowser/#/R-MMU-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Mus musculus 58349 R-MMU-6789092 https://reactome.org/PathwayBrowser/#/R-MMU-6789092 NOX2 generates superoxide anion from oxygen IEA Mus musculus 58349 R-MMU-6807053 https://reactome.org/PathwayBrowser/#/R-MMU-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Mus musculus 58349 R-MMU-6807055 https://reactome.org/PathwayBrowser/#/R-MMU-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Mus musculus 58349 R-MMU-6807064 https://reactome.org/PathwayBrowser/#/R-MMU-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Mus musculus 58349 R-MMU-6807557 https://reactome.org/PathwayBrowser/#/R-MMU-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Mus musculus 58349 R-MMU-6808487 https://reactome.org/PathwayBrowser/#/R-MMU-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 58349 R-MMU-6808496 https://reactome.org/PathwayBrowser/#/R-MMU-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 58349 R-MMU-6810594 https://reactome.org/PathwayBrowser/#/R-MMU-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 58349 R-MMU-70377 https://reactome.org/PathwayBrowser/#/R-MMU-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Mus musculus 58349 R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Mus musculus 58349 R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Mus musculus 58349 R-MMU-70938 https://reactome.org/PathwayBrowser/#/R-MMU-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Mus musculus 58349 R-MMU-71200 https://reactome.org/PathwayBrowser/#/R-MMU-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Mus musculus 58349 R-MMU-71299 https://reactome.org/PathwayBrowser/#/R-MMU-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Mus musculus 58349 R-MMU-71682 https://reactome.org/PathwayBrowser/#/R-MMU-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 58349 R-MMU-73585 https://reactome.org/PathwayBrowser/#/R-MMU-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Mus musculus 58349 R-MMU-73616 https://reactome.org/PathwayBrowser/#/R-MMU-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Mus musculus 58349 R-MMU-73646 https://reactome.org/PathwayBrowser/#/R-MMU-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Mus musculus 58349 R-MMU-74872 https://reactome.org/PathwayBrowser/#/R-MMU-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Mus musculus 58349 R-MMU-75872 https://reactome.org/PathwayBrowser/#/R-MMU-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Mus musculus 58349 R-MMU-75883 https://reactome.org/PathwayBrowser/#/R-MMU-75883 DHRS7B reduces GO3P to HXDG3P IEA Mus musculus 58349 R-MMU-804969 https://reactome.org/PathwayBrowser/#/R-MMU-804969 HSD17B1 hydrogenates E1 to EST17b IEA Mus musculus 58349 R-MMU-8862137 https://reactome.org/PathwayBrowser/#/R-MMU-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 58349 R-MMU-8862152 https://reactome.org/PathwayBrowser/#/R-MMU-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Mus musculus 58349 R-MMU-8937419 https://reactome.org/PathwayBrowser/#/R-MMU-8937419 CBR3 reduces DOX to DOXOL IEA Mus musculus 58349 R-MMU-8952873 https://reactome.org/PathwayBrowser/#/R-MMU-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Mus musculus 58349 R-MMU-8955030 https://reactome.org/PathwayBrowser/#/R-MMU-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Mus musculus 58349 R-MMU-9012036 https://reactome.org/PathwayBrowser/#/R-MMU-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Mus musculus 58349 R-MMU-9012349 https://reactome.org/PathwayBrowser/#/R-MMU-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Mus musculus 58349 R-MMU-9020255 https://reactome.org/PathwayBrowser/#/R-MMU-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Mus musculus 58349 R-MMU-9020256 https://reactome.org/PathwayBrowser/#/R-MMU-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Mus musculus 58349 R-MMU-9020262 https://reactome.org/PathwayBrowser/#/R-MMU-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Mus musculus 58349 R-MMU-9020277 https://reactome.org/PathwayBrowser/#/R-MMU-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Mus musculus 58349 R-MMU-9020278 https://reactome.org/PathwayBrowser/#/R-MMU-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Mus musculus 58349 R-MMU-9024881 https://reactome.org/PathwayBrowser/#/R-MMU-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Mus musculus 58349 R-MMU-9024983 https://reactome.org/PathwayBrowser/#/R-MMU-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Mus musculus 58349 R-MMU-9025995 https://reactome.org/PathwayBrowser/#/R-MMU-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Mus musculus 58349 R-MMU-9025999 https://reactome.org/PathwayBrowser/#/R-MMU-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Mus musculus 58349 R-MMU-9026007 https://reactome.org/PathwayBrowser/#/R-MMU-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Mus musculus 58349 R-MMU-9027043 https://reactome.org/PathwayBrowser/#/R-MMU-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Mus musculus 58349 R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 58349 R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 58349 R-MMU-9037761 https://reactome.org/PathwayBrowser/#/R-MMU-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Mus musculus 58349 R-MMU-917811 https://reactome.org/PathwayBrowser/#/R-MMU-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Mus musculus 58349 R-MMU-9705713 https://reactome.org/PathwayBrowser/#/R-MMU-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Mus musculus 58349 R-MMU-9705714 https://reactome.org/PathwayBrowser/#/R-MMU-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Mus musculus 58349 R-MMU-9709098 https://reactome.org/PathwayBrowser/#/R-MMU-9709098 DHFR dimer reduces FOLA to DHF IEA Mus musculus 58349 R-MMU-9753285 https://reactome.org/PathwayBrowser/#/R-MMU-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Mus musculus 58349 R-MMU-9755937 https://reactome.org/PathwayBrowser/#/R-MMU-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Mus musculus 58349 R-MMU-9756138 https://reactome.org/PathwayBrowser/#/R-MMU-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Mus musculus 58349 R-MMU-9756162 https://reactome.org/PathwayBrowser/#/R-MMU-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Mus musculus 58349 R-MMU-9756169 https://reactome.org/PathwayBrowser/#/R-MMU-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Mus musculus 58349 R-MMU-9756180 https://reactome.org/PathwayBrowser/#/R-MMU-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Mus musculus 58349 R-MMU-975629 https://reactome.org/PathwayBrowser/#/R-MMU-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Mus musculus 58349 R-MMU-9757706 https://reactome.org/PathwayBrowser/#/R-MMU-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Mus musculus 58349 R-MMU-9758682 https://reactome.org/PathwayBrowser/#/R-MMU-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Mus musculus 58349 R-MMU-9759259 https://reactome.org/PathwayBrowser/#/R-MMU-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Mus musculus 58349 R-MTU-879322 https://reactome.org/PathwayBrowser/#/R-MTU-879322 mycothione is reduced to mycothiol TAS Mycobacterium tuberculosis 58349 R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 58349 R-MTU-964842 https://reactome.org/PathwayBrowser/#/R-MTU-964842 Shikimate results from hydration of DHS TAS Mycobacterium tuberculosis 58349 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 58349 R-PFA-193064 https://reactome.org/PathwayBrowser/#/R-PFA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Plasmodium falciparum 58349 R-PFA-200644 https://reactome.org/PathwayBrowser/#/R-PFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Plasmodium falciparum 58349 R-PFA-200718 https://reactome.org/PathwayBrowser/#/R-PFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Plasmodium falciparum 58349 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 58349 R-PFA-2395517 https://reactome.org/PathwayBrowser/#/R-PFA-2395517 NADPH transfers electrons to FDXR IEA Plasmodium falciparum 58349 R-PFA-3323079 https://reactome.org/PathwayBrowser/#/R-PFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 58349 R-PFA-418436 https://reactome.org/PathwayBrowser/#/R-PFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Plasmodium falciparum 58349 R-PFA-428123 https://reactome.org/PathwayBrowser/#/R-PFA-428123 KDSR reduces 3-ketosphingoid IEA Plasmodium falciparum 58349 R-PFA-4419979 https://reactome.org/PathwayBrowser/#/R-PFA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Plasmodium falciparum 58349 R-PFA-450971 https://reactome.org/PathwayBrowser/#/R-PFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Plasmodium falciparum 58349 R-PFA-450984 https://reactome.org/PathwayBrowser/#/R-PFA-450984 IDH2 dimer decarboxylates isocitrate IEA Plasmodium falciparum 58349 R-PFA-5263614 https://reactome.org/PathwayBrowser/#/R-PFA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Plasmodium falciparum 58349 R-PFA-5263616 https://reactome.org/PathwayBrowser/#/R-PFA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Plasmodium falciparum 58349 R-PFA-548818 https://reactome.org/PathwayBrowser/#/R-PFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Plasmodium falciparum 58349 R-PFA-548831 https://reactome.org/PathwayBrowser/#/R-PFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Plasmodium falciparum 58349 R-PFA-6783955 https://reactome.org/PathwayBrowser/#/R-PFA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 58349 R-PFA-6787642 https://reactome.org/PathwayBrowser/#/R-PFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Plasmodium falciparum 58349 R-PFA-70377 https://reactome.org/PathwayBrowser/#/R-PFA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Plasmodium falciparum 58349 R-PFA-71682 https://reactome.org/PathwayBrowser/#/R-PFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 58349 R-PFA-73646 https://reactome.org/PathwayBrowser/#/R-PFA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Plasmodium falciparum 58349 R-PFA-8862152 https://reactome.org/PathwayBrowser/#/R-PFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Plasmodium falciparum 58349 R-PFA-8955030 https://reactome.org/PathwayBrowser/#/R-PFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Plasmodium falciparum 58349 R-PFA-9705714 https://reactome.org/PathwayBrowser/#/R-PFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Plasmodium falciparum 58349 R-RNO-1222376 https://reactome.org/PathwayBrowser/#/R-RNO-1222376 NOX2 generates superoxide from oxygen IEA Rattus norvegicus 58349 R-RNO-1475414 https://reactome.org/PathwayBrowser/#/R-RNO-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Rattus norvegicus 58349 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 58349 R-RNO-1497869 https://reactome.org/PathwayBrowser/#/R-RNO-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Rattus norvegicus 58349 R-RNO-156526 https://reactome.org/PathwayBrowser/#/R-RNO-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Rattus norvegicus 58349 R-RNO-1655453 https://reactome.org/PathwayBrowser/#/R-RNO-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Rattus norvegicus 58349 R-RNO-189384 https://reactome.org/PathwayBrowser/#/R-RNO-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Rattus norvegicus 58349 R-RNO-189398 https://reactome.org/PathwayBrowser/#/R-RNO-189398 HMOX1 dimer, HMOX2 cleave heme IEA Rattus norvegicus 58349 R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 58349 R-RNO-191352 https://reactome.org/PathwayBrowser/#/R-RNO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Rattus norvegicus 58349 R-RNO-191402 https://reactome.org/PathwayBrowser/#/R-RNO-191402 Reduction of presqualene diphosphate to form squalene IEA Rattus norvegicus 58349 R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 58349 R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 58349 R-RNO-191999 https://reactome.org/PathwayBrowser/#/R-RNO-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Rattus norvegicus 58349 R-RNO-192033 https://reactome.org/PathwayBrowser/#/R-RNO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Rattus norvegicus 58349 R-RNO-192036 https://reactome.org/PathwayBrowser/#/R-RNO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Rattus norvegicus 58349 R-RNO-192042 https://reactome.org/PathwayBrowser/#/R-RNO-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 58349 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 58349 R-RNO-192054 https://reactome.org/PathwayBrowser/#/R-RNO-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Rattus norvegicus 58349 R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 58349 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 58349 R-RNO-192067 https://reactome.org/PathwayBrowser/#/R-RNO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Rattus norvegicus 58349 R-RNO-192123 https://reactome.org/PathwayBrowser/#/R-RNO-192123 CYP27A1 27-hydroxylates CHOL IEA Rattus norvegicus 58349 R-RNO-192157 https://reactome.org/PathwayBrowser/#/R-RNO-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Rattus norvegicus 58349 R-RNO-192160 https://reactome.org/PathwayBrowser/#/R-RNO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Rattus norvegicus 58349 R-RNO-192178 https://reactome.org/PathwayBrowser/#/R-RNO-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Rattus norvegicus 58349 R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 58349 R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 58349 R-RNO-193064 https://reactome.org/PathwayBrowser/#/R-RNO-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Rattus norvegicus 58349 R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 58349 R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 58349 R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 58349 R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 58349 R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 58349 R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 58349 R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 58349 R-RNO-193393 https://reactome.org/PathwayBrowser/#/R-RNO-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Rattus norvegicus 58349 R-RNO-193460 https://reactome.org/PathwayBrowser/#/R-RNO-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Rattus norvegicus 58349 R-RNO-193497 https://reactome.org/PathwayBrowser/#/R-RNO-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Rattus norvegicus 58349 R-RNO-193709 https://reactome.org/PathwayBrowser/#/R-RNO-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Rattus norvegicus 58349 R-RNO-193713 https://reactome.org/PathwayBrowser/#/R-RNO-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Rattus norvegicus 58349 R-RNO-193719 https://reactome.org/PathwayBrowser/#/R-RNO-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 58349 R-RNO-193737 https://reactome.org/PathwayBrowser/#/R-RNO-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Rattus norvegicus 58349 R-RNO-193746 https://reactome.org/PathwayBrowser/#/R-RNO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 58349 R-RNO-193755 https://reactome.org/PathwayBrowser/#/R-RNO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Rattus norvegicus 58349 R-RNO-193758 https://reactome.org/PathwayBrowser/#/R-RNO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Rattus norvegicus 58349 R-RNO-193780 https://reactome.org/PathwayBrowser/#/R-RNO-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 58349 R-RNO-193781 https://reactome.org/PathwayBrowser/#/R-RNO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Rattus norvegicus 58349 R-RNO-193787 https://reactome.org/PathwayBrowser/#/R-RNO-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Rattus norvegicus 58349 R-RNO-193792 https://reactome.org/PathwayBrowser/#/R-RNO-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Rattus norvegicus 58349 R-RNO-193800 https://reactome.org/PathwayBrowser/#/R-RNO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Rattus norvegicus 58349 R-RNO-193821 https://reactome.org/PathwayBrowser/#/R-RNO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Rattus norvegicus 58349 R-RNO-193824 https://reactome.org/PathwayBrowser/#/R-RNO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Rattus norvegicus 58349 R-RNO-193841 https://reactome.org/PathwayBrowser/#/R-RNO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Rattus norvegicus 58349 R-RNO-193845 https://reactome.org/PathwayBrowser/#/R-RNO-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Rattus norvegicus 58349 R-RNO-193964 https://reactome.org/PathwayBrowser/#/R-RNO-193964 CYP21A2 21-hydroxylates PROG IEA Rattus norvegicus 58349 R-RNO-193965 https://reactome.org/PathwayBrowser/#/R-RNO-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Rattus norvegicus 58349 R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 58349 R-RNO-193995 https://reactome.org/PathwayBrowser/#/R-RNO-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Rattus norvegicus 58349 R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 58349 R-RNO-194017 https://reactome.org/PathwayBrowser/#/R-RNO-194017 CYP11B2 oxidises 11DCORST to CORST IEA Rattus norvegicus 58349 R-RNO-194023 https://reactome.org/PathwayBrowser/#/R-RNO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Rattus norvegicus 58349 R-RNO-194632 https://reactome.org/PathwayBrowser/#/R-RNO-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Rattus norvegicus 58349 R-RNO-194641 https://reactome.org/PathwayBrowser/#/R-RNO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 58349 R-RNO-194669 https://reactome.org/PathwayBrowser/#/R-RNO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 58349 R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 58349 R-RNO-194689 https://reactome.org/PathwayBrowser/#/R-RNO-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 58349 R-RNO-194698 https://reactome.org/PathwayBrowser/#/R-RNO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Rattus norvegicus 58349 R-RNO-195664 https://reactome.org/PathwayBrowser/#/R-RNO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Rattus norvegicus 58349 R-RNO-196060 https://reactome.org/PathwayBrowser/#/R-RNO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Rattus norvegicus 58349 R-RNO-196402 https://reactome.org/PathwayBrowser/#/R-RNO-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Rattus norvegicus 58349 R-RNO-196417 https://reactome.org/PathwayBrowser/#/R-RNO-196417 Reduction of desmosterol to cholesterol IEA Rattus norvegicus 58349 R-RNO-197198 https://reactome.org/PathwayBrowser/#/R-RNO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 58349 R-RNO-197963 https://reactome.org/PathwayBrowser/#/R-RNO-197963 DHFR2 reduces FOLA to DHF IEA Rattus norvegicus 58349 R-RNO-197972 https://reactome.org/PathwayBrowser/#/R-RNO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Rattus norvegicus 58349 R-RNO-200644 https://reactome.org/PathwayBrowser/#/R-RNO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Rattus norvegicus 58349 R-RNO-200676 https://reactome.org/PathwayBrowser/#/R-RNO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Rattus norvegicus 58349 R-RNO-200718 https://reactome.org/PathwayBrowser/#/R-RNO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Rattus norvegicus 58349 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 58349 R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 58349 R-RNO-209772 https://reactome.org/PathwayBrowser/#/R-RNO-209772 Thyroxine is deiodinated to triiodothyronine IEA Rattus norvegicus 58349 R-RNO-209845 https://reactome.org/PathwayBrowser/#/R-RNO-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Rattus norvegicus 58349 R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 58349 R-RNO-211873 https://reactome.org/PathwayBrowser/#/R-RNO-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Rattus norvegicus 58349 R-RNO-211923 https://reactome.org/PathwayBrowser/#/R-RNO-211923 CYP26C1 4-hydroxylates 9cRA IEA Rattus norvegicus 58349 R-RNO-211950 https://reactome.org/PathwayBrowser/#/R-RNO-211950 CYP24A1 24-hydroxylates CTL IEA Rattus norvegicus 58349 R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 58349 R-RNO-2161549 https://reactome.org/PathwayBrowser/#/R-RNO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Rattus norvegicus 58349 R-RNO-2161614 https://reactome.org/PathwayBrowser/#/R-RNO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Rattus norvegicus 58349 R-RNO-2161651 https://reactome.org/PathwayBrowser/#/R-RNO-2161651 PGE2 is converted to PGF2a by CBR1 IEA Rattus norvegicus 58349 R-RNO-2161745 https://reactome.org/PathwayBrowser/#/R-RNO-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 58349 R-RNO-2161792 https://reactome.org/PathwayBrowser/#/R-RNO-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 58349 R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus 58349 R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Rattus norvegicus 58349 R-RNO-2161951 https://reactome.org/PathwayBrowser/#/R-RNO-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Rattus norvegicus 58349 R-RNO-2395517 https://reactome.org/PathwayBrowser/#/R-RNO-2395517 NADPH transfers electrons to FDXR IEA Rattus norvegicus 58349 R-RNO-2408514 https://reactome.org/PathwayBrowser/#/R-RNO-2408514 GSSeSG is reduced to GSSeH and GSH by Gsr TAS Rattus norvegicus 58349 R-RNO-2464822 https://reactome.org/PathwayBrowser/#/R-RNO-2464822 RDH12 reduces atRAL to atROL IEA Rattus norvegicus 58349 R-RNO-2465940 https://reactome.org/PathwayBrowser/#/R-RNO-2465940 atRAL is reduced to atROL IEA Rattus norvegicus 58349 R-RNO-2855252 https://reactome.org/PathwayBrowser/#/R-RNO-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 58349 R-RNO-3149518 https://reactome.org/PathwayBrowser/#/R-RNO-3149518 MTRR reduces cob(II)alamin to meCbl IEA Rattus norvegicus 58349 R-RNO-3149519 https://reactome.org/PathwayBrowser/#/R-RNO-3149519 MMACHC decyanates CNCbl IEA Rattus norvegicus 58349 R-RNO-3323050 https://reactome.org/PathwayBrowser/#/R-RNO-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Rattus norvegicus 58349 R-RNO-3323079 https://reactome.org/PathwayBrowser/#/R-RNO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 58349 R-RNO-350869 https://reactome.org/PathwayBrowser/#/R-RNO-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Rattus norvegicus 58349 R-RNO-389540 https://reactome.org/PathwayBrowser/#/R-RNO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 58349 R-RNO-390425 https://reactome.org/PathwayBrowser/#/R-RNO-390425 FAR1 reduces PalmCoA to HXOL IEA Rattus norvegicus 58349 R-RNO-390438 https://reactome.org/PathwayBrowser/#/R-RNO-390438 FAR2 reduces PalmCoA to HXOL IEA Rattus norvegicus 58349 R-RNO-418436 https://reactome.org/PathwayBrowser/#/R-RNO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Rattus norvegicus 58349 R-RNO-428123 https://reactome.org/PathwayBrowser/#/R-RNO-428123 KDSR reduces 3-ketosphingoid IEA Rattus norvegicus 58349 R-RNO-4419979 https://reactome.org/PathwayBrowser/#/R-RNO-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Rattus norvegicus 58349 R-RNO-450971 https://reactome.org/PathwayBrowser/#/R-RNO-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Rattus norvegicus 58349 R-RNO-450984 https://reactome.org/PathwayBrowser/#/R-RNO-450984 IDH2 dimer decarboxylates isocitrate IEA Rattus norvegicus 58349 R-RNO-469659 https://reactome.org/PathwayBrowser/#/R-RNO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 58349 R-RNO-508040 https://reactome.org/PathwayBrowser/#/R-RNO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Rattus norvegicus 58349 R-RNO-514604 https://reactome.org/PathwayBrowser/#/R-RNO-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Rattus norvegicus 58349 R-RNO-5218841 https://reactome.org/PathwayBrowser/#/R-RNO-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Rattus norvegicus 58349 R-RNO-5263614 https://reactome.org/PathwayBrowser/#/R-RNO-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Rattus norvegicus 58349 R-RNO-5263616 https://reactome.org/PathwayBrowser/#/R-RNO-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Rattus norvegicus 58349 R-RNO-5340226 https://reactome.org/PathwayBrowser/#/R-RNO-5340226 CYGB dioxygenates NO IEA Rattus norvegicus 58349 R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 58349 R-RNO-5419165 https://reactome.org/PathwayBrowser/#/R-RNO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Rattus norvegicus 58349 R-RNO-5423637 https://reactome.org/PathwayBrowser/#/R-RNO-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Rattus norvegicus 58349 R-RNO-5423647 https://reactome.org/PathwayBrowser/#/R-RNO-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Rattus norvegicus 58349 R-RNO-5423664 https://reactome.org/PathwayBrowser/#/R-RNO-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Rattus norvegicus 58349 R-RNO-5423672 https://reactome.org/PathwayBrowser/#/R-RNO-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Rattus norvegicus 58349 R-RNO-5423678 https://reactome.org/PathwayBrowser/#/R-RNO-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Rattus norvegicus 58349 R-RNO-548818 https://reactome.org/PathwayBrowser/#/R-RNO-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Rattus norvegicus 58349 R-RNO-548831 https://reactome.org/PathwayBrowser/#/R-RNO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Rattus norvegicus 58349 R-RNO-5615668 https://reactome.org/PathwayBrowser/#/R-RNO-5615668 AKR1C3 reduces atRAL to atROL IEA Rattus norvegicus 58349 R-RNO-5652172 https://reactome.org/PathwayBrowser/#/R-RNO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Rattus norvegicus 58349 R-RNO-5661240 https://reactome.org/PathwayBrowser/#/R-RNO-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Rattus norvegicus 58349 R-RNO-5661256 https://reactome.org/PathwayBrowser/#/R-RNO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Rattus norvegicus 58349 R-RNO-5668629 https://reactome.org/PathwayBrowser/#/R-RNO-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Rattus norvegicus 58349 R-RNO-5668718 https://reactome.org/PathwayBrowser/#/R-RNO-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 58349 R-RNO-5668731 https://reactome.org/PathwayBrowser/#/R-RNO-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 58349 R-RNO-5692232 https://reactome.org/PathwayBrowser/#/R-RNO-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Rattus norvegicus 58349 R-RNO-5692283 https://reactome.org/PathwayBrowser/#/R-RNO-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Rattus norvegicus 58349 R-RNO-5693390 https://reactome.org/PathwayBrowser/#/R-RNO-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Rattus norvegicus 58349 R-RNO-5696822 https://reactome.org/PathwayBrowser/#/R-RNO-5696822 AKR1B15 reduces EST17b to E1 IEA Rattus norvegicus 58349 R-RNO-6783955 https://reactome.org/PathwayBrowser/#/R-RNO-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 58349 R-RNO-6786239 https://reactome.org/PathwayBrowser/#/R-RNO-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Rattus norvegicus 58349 R-RNO-6787642 https://reactome.org/PathwayBrowser/#/R-RNO-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Rattus norvegicus 58349 R-RNO-6789092 https://reactome.org/PathwayBrowser/#/R-RNO-6789092 NOX2 generates superoxide anion from oxygen IEA Rattus norvegicus 58349 R-RNO-6807053 https://reactome.org/PathwayBrowser/#/R-RNO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Rattus norvegicus 58349 R-RNO-6807055 https://reactome.org/PathwayBrowser/#/R-RNO-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Rattus norvegicus 58349 R-RNO-6807064 https://reactome.org/PathwayBrowser/#/R-RNO-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Rattus norvegicus 58349 R-RNO-6807557 https://reactome.org/PathwayBrowser/#/R-RNO-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Rattus norvegicus 58349 R-RNO-6808487 https://reactome.org/PathwayBrowser/#/R-RNO-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 58349 R-RNO-6808496 https://reactome.org/PathwayBrowser/#/R-RNO-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 58349 R-RNO-6810594 https://reactome.org/PathwayBrowser/#/R-RNO-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 58349 R-RNO-70377 https://reactome.org/PathwayBrowser/#/R-RNO-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Rattus norvegicus 58349 R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Rattus norvegicus 58349 R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Rattus norvegicus 58349 R-RNO-70938 https://reactome.org/PathwayBrowser/#/R-RNO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Rattus norvegicus 58349 R-RNO-71200 https://reactome.org/PathwayBrowser/#/R-RNO-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Rattus norvegicus 58349 R-RNO-71299 https://reactome.org/PathwayBrowser/#/R-RNO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Rattus norvegicus 58349 R-RNO-71682 https://reactome.org/PathwayBrowser/#/R-RNO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 58349 R-RNO-73585 https://reactome.org/PathwayBrowser/#/R-RNO-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Rattus norvegicus 58349 R-RNO-73616 https://reactome.org/PathwayBrowser/#/R-RNO-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Rattus norvegicus 58349 R-RNO-73646 https://reactome.org/PathwayBrowser/#/R-RNO-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Rattus norvegicus 58349 R-RNO-74872 https://reactome.org/PathwayBrowser/#/R-RNO-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 58349 R-RNO-75872 https://reactome.org/PathwayBrowser/#/R-RNO-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Rattus norvegicus 58349 R-RNO-75883 https://reactome.org/PathwayBrowser/#/R-RNO-75883 DHRS7B reduces GO3P to HXDG3P IEA Rattus norvegicus 58349 R-RNO-804969 https://reactome.org/PathwayBrowser/#/R-RNO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Rattus norvegicus 58349 R-RNO-8862137 https://reactome.org/PathwayBrowser/#/R-RNO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 58349 R-RNO-8862152 https://reactome.org/PathwayBrowser/#/R-RNO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Rattus norvegicus 58349 R-RNO-8937419 https://reactome.org/PathwayBrowser/#/R-RNO-8937419 CBR3 reduces DOX to DOXOL IEA Rattus norvegicus 58349 R-RNO-8952873 https://reactome.org/PathwayBrowser/#/R-RNO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Rattus norvegicus 58349 R-RNO-8955030 https://reactome.org/PathwayBrowser/#/R-RNO-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 58349 R-RNO-9012036 https://reactome.org/PathwayBrowser/#/R-RNO-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 58349 R-RNO-9012349 https://reactome.org/PathwayBrowser/#/R-RNO-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 58349 R-RNO-9020255 https://reactome.org/PathwayBrowser/#/R-RNO-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Rattus norvegicus 58349 R-RNO-9020256 https://reactome.org/PathwayBrowser/#/R-RNO-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Rattus norvegicus 58349 R-RNO-9020262 https://reactome.org/PathwayBrowser/#/R-RNO-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Rattus norvegicus 58349 R-RNO-9020277 https://reactome.org/PathwayBrowser/#/R-RNO-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Rattus norvegicus 58349 R-RNO-9020278 https://reactome.org/PathwayBrowser/#/R-RNO-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Rattus norvegicus 58349 R-RNO-9024881 https://reactome.org/PathwayBrowser/#/R-RNO-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Rattus norvegicus 58349 R-RNO-9024983 https://reactome.org/PathwayBrowser/#/R-RNO-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Rattus norvegicus 58349 R-RNO-9025995 https://reactome.org/PathwayBrowser/#/R-RNO-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Rattus norvegicus 58349 R-RNO-9025999 https://reactome.org/PathwayBrowser/#/R-RNO-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Rattus norvegicus 58349 R-RNO-9026007 https://reactome.org/PathwayBrowser/#/R-RNO-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Rattus norvegicus 58349 R-RNO-9027043 https://reactome.org/PathwayBrowser/#/R-RNO-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Rattus norvegicus 58349 R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 58349 R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 58349 R-RNO-9037761 https://reactome.org/PathwayBrowser/#/R-RNO-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Rattus norvegicus 58349 R-RNO-917811 https://reactome.org/PathwayBrowser/#/R-RNO-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Rattus norvegicus 58349 R-RNO-9705713 https://reactome.org/PathwayBrowser/#/R-RNO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 58349 R-RNO-9705714 https://reactome.org/PathwayBrowser/#/R-RNO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 58349 R-RNO-9709098 https://reactome.org/PathwayBrowser/#/R-RNO-9709098 DHFR dimer reduces FOLA to DHF IEA Rattus norvegicus 58349 R-RNO-9753285 https://reactome.org/PathwayBrowser/#/R-RNO-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Rattus norvegicus 58349 R-RNO-9755937 https://reactome.org/PathwayBrowser/#/R-RNO-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Rattus norvegicus 58349 R-RNO-9756138 https://reactome.org/PathwayBrowser/#/R-RNO-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Rattus norvegicus 58349 R-RNO-9756162 https://reactome.org/PathwayBrowser/#/R-RNO-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Rattus norvegicus 58349 R-RNO-9756169 https://reactome.org/PathwayBrowser/#/R-RNO-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Rattus norvegicus 58349 R-RNO-9756180 https://reactome.org/PathwayBrowser/#/R-RNO-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Rattus norvegicus 58349 R-RNO-975629 https://reactome.org/PathwayBrowser/#/R-RNO-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 58349 R-RNO-9757706 https://reactome.org/PathwayBrowser/#/R-RNO-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Rattus norvegicus 58349 R-RNO-9758682 https://reactome.org/PathwayBrowser/#/R-RNO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Rattus norvegicus 58349 R-RNO-9759259 https://reactome.org/PathwayBrowser/#/R-RNO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Rattus norvegicus 58349 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 58349 R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 58349 R-SCE-191352 https://reactome.org/PathwayBrowser/#/R-SCE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Saccharomyces cerevisiae 58349 R-SCE-191402 https://reactome.org/PathwayBrowser/#/R-SCE-191402 Reduction of presqualene diphosphate to form squalene IEA Saccharomyces cerevisiae 58349 R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 58349 R-SCE-192033 https://reactome.org/PathwayBrowser/#/R-SCE-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Saccharomyces cerevisiae 58349 R-SCE-192036 https://reactome.org/PathwayBrowser/#/R-SCE-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Saccharomyces cerevisiae 58349 R-SCE-192067 https://reactome.org/PathwayBrowser/#/R-SCE-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Saccharomyces cerevisiae 58349 R-SCE-192160 https://reactome.org/PathwayBrowser/#/R-SCE-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Saccharomyces cerevisiae 58349 R-SCE-193746 https://reactome.org/PathwayBrowser/#/R-SCE-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Saccharomyces cerevisiae 58349 R-SCE-193755 https://reactome.org/PathwayBrowser/#/R-SCE-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Saccharomyces cerevisiae 58349 R-SCE-193758 https://reactome.org/PathwayBrowser/#/R-SCE-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Saccharomyces cerevisiae 58349 R-SCE-193781 https://reactome.org/PathwayBrowser/#/R-SCE-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Saccharomyces cerevisiae 58349 R-SCE-193800 https://reactome.org/PathwayBrowser/#/R-SCE-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Saccharomyces cerevisiae 58349 R-SCE-193821 https://reactome.org/PathwayBrowser/#/R-SCE-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Saccharomyces cerevisiae 58349 R-SCE-193824 https://reactome.org/PathwayBrowser/#/R-SCE-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Saccharomyces cerevisiae 58349 R-SCE-193841 https://reactome.org/PathwayBrowser/#/R-SCE-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Saccharomyces cerevisiae 58349 R-SCE-194641 https://reactome.org/PathwayBrowser/#/R-SCE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 58349 R-SCE-194669 https://reactome.org/PathwayBrowser/#/R-SCE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 58349 R-SCE-194678 https://reactome.org/PathwayBrowser/#/R-SCE-194678 CYP51A1 demethylates LNSOL IEA Saccharomyces cerevisiae 58349 R-SCE-194698 https://reactome.org/PathwayBrowser/#/R-SCE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Saccharomyces cerevisiae 58349 R-SCE-195664 https://reactome.org/PathwayBrowser/#/R-SCE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Saccharomyces cerevisiae 58349 R-SCE-196060 https://reactome.org/PathwayBrowser/#/R-SCE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Saccharomyces cerevisiae 58349 R-SCE-197198 https://reactome.org/PathwayBrowser/#/R-SCE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Saccharomyces cerevisiae 58349 R-SCE-197963 https://reactome.org/PathwayBrowser/#/R-SCE-197963 DHFR2 reduces FOLA to DHF IEA Saccharomyces cerevisiae 58349 R-SCE-197972 https://reactome.org/PathwayBrowser/#/R-SCE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Saccharomyces cerevisiae 58349 R-SCE-200644 https://reactome.org/PathwayBrowser/#/R-SCE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Saccharomyces cerevisiae 58349 R-SCE-200676 https://reactome.org/PathwayBrowser/#/R-SCE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Saccharomyces cerevisiae 58349 R-SCE-200718 https://reactome.org/PathwayBrowser/#/R-SCE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Saccharomyces cerevisiae 58349 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 58349 R-SCE-2161549 https://reactome.org/PathwayBrowser/#/R-SCE-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Saccharomyces cerevisiae 58349 R-SCE-2161614 https://reactome.org/PathwayBrowser/#/R-SCE-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Saccharomyces cerevisiae 58349 R-SCE-2164813 https://reactome.org/PathwayBrowser/#/R-SCE-2164813 HMPhOH is hydroxylated to MDMQ6H2 by HMPhOH monooxygenase TAS Saccharomyces cerevisiae 58349 R-SCE-2395517 https://reactome.org/PathwayBrowser/#/R-SCE-2395517 NADPH transfers electrons to FDXR IEA Saccharomyces cerevisiae 58349 R-SCE-2408518 https://reactome.org/PathwayBrowser/#/R-SCE-2408518 PAPSe is reduced to SeO3(2-) by MET16 TAS Saccharomyces cerevisiae 58349 R-SCE-2465940 https://reactome.org/PathwayBrowser/#/R-SCE-2465940 atRAL is reduced to atROL IEA Saccharomyces cerevisiae 58349 R-SCE-2564819 https://reactome.org/PathwayBrowser/#/R-SCE-2564819 NADPH reduces TAH18:DRE2 TAS Saccharomyces cerevisiae 58349 R-SCE-3323079 https://reactome.org/PathwayBrowser/#/R-SCE-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 58349 R-SCE-389540 https://reactome.org/PathwayBrowser/#/R-SCE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 58349 R-SCE-418436 https://reactome.org/PathwayBrowser/#/R-SCE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Saccharomyces cerevisiae 58349 R-SCE-428123 https://reactome.org/PathwayBrowser/#/R-SCE-428123 KDSR reduces 3-ketosphingoid IEA Saccharomyces cerevisiae 58349 R-SCE-4419979 https://reactome.org/PathwayBrowser/#/R-SCE-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Saccharomyces cerevisiae 58349 R-SCE-508040 https://reactome.org/PathwayBrowser/#/R-SCE-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Saccharomyces cerevisiae 58349 R-SCE-5419165 https://reactome.org/PathwayBrowser/#/R-SCE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Saccharomyces cerevisiae 58349 R-SCE-548831 https://reactome.org/PathwayBrowser/#/R-SCE-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Saccharomyces cerevisiae 58349 R-SCE-5615668 https://reactome.org/PathwayBrowser/#/R-SCE-5615668 AKR1C3 reduces atRAL to atROL IEA Saccharomyces cerevisiae 58349 R-SCE-5652172 https://reactome.org/PathwayBrowser/#/R-SCE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Saccharomyces cerevisiae 58349 R-SCE-5661256 https://reactome.org/PathwayBrowser/#/R-SCE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Saccharomyces cerevisiae 58349 R-SCE-5692232 https://reactome.org/PathwayBrowser/#/R-SCE-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Saccharomyces cerevisiae 58349 R-SCE-5692283 https://reactome.org/PathwayBrowser/#/R-SCE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Saccharomyces cerevisiae 58349 R-SCE-5693390 https://reactome.org/PathwayBrowser/#/R-SCE-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Saccharomyces cerevisiae 58349 R-SCE-5696822 https://reactome.org/PathwayBrowser/#/R-SCE-5696822 AKR1B15 reduces EST17b to E1 IEA Saccharomyces cerevisiae 58349 R-SCE-6783955 https://reactome.org/PathwayBrowser/#/R-SCE-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 58349 R-SCE-6807053 https://reactome.org/PathwayBrowser/#/R-SCE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Saccharomyces cerevisiae 58349 R-SCE-6807557 https://reactome.org/PathwayBrowser/#/R-SCE-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Saccharomyces cerevisiae 58349 R-SCE-70377 https://reactome.org/PathwayBrowser/#/R-SCE-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Saccharomyces cerevisiae 58349 R-SCE-70938 https://reactome.org/PathwayBrowser/#/R-SCE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Saccharomyces cerevisiae 58349 R-SCE-71200 https://reactome.org/PathwayBrowser/#/R-SCE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Saccharomyces cerevisiae 58349 R-SCE-71299 https://reactome.org/PathwayBrowser/#/R-SCE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 58349 R-SCE-71682 https://reactome.org/PathwayBrowser/#/R-SCE-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 58349 R-SCE-8862152 https://reactome.org/PathwayBrowser/#/R-SCE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Saccharomyces cerevisiae 58349 R-SCE-8952873 https://reactome.org/PathwayBrowser/#/R-SCE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Saccharomyces cerevisiae 58349 R-SCE-9705714 https://reactome.org/PathwayBrowser/#/R-SCE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Saccharomyces cerevisiae 58349 R-SCE-9709098 https://reactome.org/PathwayBrowser/#/R-SCE-9709098 DHFR dimer reduces FOLA to DHF IEA Saccharomyces cerevisiae 58349 R-SCE-9758682 https://reactome.org/PathwayBrowser/#/R-SCE-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Saccharomyces cerevisiae 58349 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 58349 R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 58349 R-SPO-191352 https://reactome.org/PathwayBrowser/#/R-SPO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Schizosaccharomyces pombe 58349 R-SPO-191402 https://reactome.org/PathwayBrowser/#/R-SPO-191402 Reduction of presqualene diphosphate to form squalene IEA Schizosaccharomyces pombe 58349 R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 58349 R-SPO-192033 https://reactome.org/PathwayBrowser/#/R-SPO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Schizosaccharomyces pombe 58349 R-SPO-192036 https://reactome.org/PathwayBrowser/#/R-SPO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Schizosaccharomyces pombe 58349 R-SPO-192067 https://reactome.org/PathwayBrowser/#/R-SPO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Schizosaccharomyces pombe 58349 R-SPO-192160 https://reactome.org/PathwayBrowser/#/R-SPO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Schizosaccharomyces pombe 58349 R-SPO-193746 https://reactome.org/PathwayBrowser/#/R-SPO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Schizosaccharomyces pombe 58349 R-SPO-193755 https://reactome.org/PathwayBrowser/#/R-SPO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Schizosaccharomyces pombe 58349 R-SPO-193758 https://reactome.org/PathwayBrowser/#/R-SPO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Schizosaccharomyces pombe 58349 R-SPO-193781 https://reactome.org/PathwayBrowser/#/R-SPO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Schizosaccharomyces pombe 58349 R-SPO-193800 https://reactome.org/PathwayBrowser/#/R-SPO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Schizosaccharomyces pombe 58349 R-SPO-193821 https://reactome.org/PathwayBrowser/#/R-SPO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Schizosaccharomyces pombe 58349 R-SPO-193824 https://reactome.org/PathwayBrowser/#/R-SPO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Schizosaccharomyces pombe 58349 R-SPO-193841 https://reactome.org/PathwayBrowser/#/R-SPO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Schizosaccharomyces pombe 58349 R-SPO-194023 https://reactome.org/PathwayBrowser/#/R-SPO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Schizosaccharomyces pombe 58349 R-SPO-194641 https://reactome.org/PathwayBrowser/#/R-SPO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 58349 R-SPO-194669 https://reactome.org/PathwayBrowser/#/R-SPO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 58349 R-SPO-194678 https://reactome.org/PathwayBrowser/#/R-SPO-194678 CYP51A1 demethylates LNSOL IEA Schizosaccharomyces pombe 58349 R-SPO-194698 https://reactome.org/PathwayBrowser/#/R-SPO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Schizosaccharomyces pombe 58349 R-SPO-195664 https://reactome.org/PathwayBrowser/#/R-SPO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Schizosaccharomyces pombe 58349 R-SPO-196060 https://reactome.org/PathwayBrowser/#/R-SPO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Schizosaccharomyces pombe 58349 R-SPO-197198 https://reactome.org/PathwayBrowser/#/R-SPO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Schizosaccharomyces pombe 58349 R-SPO-197963 https://reactome.org/PathwayBrowser/#/R-SPO-197963 DHFR2 reduces FOLA to DHF IEA Schizosaccharomyces pombe 58349 R-SPO-197972 https://reactome.org/PathwayBrowser/#/R-SPO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Schizosaccharomyces pombe 58349 R-SPO-200644 https://reactome.org/PathwayBrowser/#/R-SPO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Schizosaccharomyces pombe 58349 R-SPO-200676 https://reactome.org/PathwayBrowser/#/R-SPO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Schizosaccharomyces pombe 58349 R-SPO-200718 https://reactome.org/PathwayBrowser/#/R-SPO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Schizosaccharomyces pombe 58349 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 58349 R-SPO-2161549 https://reactome.org/PathwayBrowser/#/R-SPO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Schizosaccharomyces pombe 58349 R-SPO-2161614 https://reactome.org/PathwayBrowser/#/R-SPO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Schizosaccharomyces pombe 58349 R-SPO-2395517 https://reactome.org/PathwayBrowser/#/R-SPO-2395517 NADPH transfers electrons to FDXR IEA Schizosaccharomyces pombe 58349 R-SPO-3323079 https://reactome.org/PathwayBrowser/#/R-SPO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 58349 R-SPO-389540 https://reactome.org/PathwayBrowser/#/R-SPO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 58349 R-SPO-418436 https://reactome.org/PathwayBrowser/#/R-SPO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Schizosaccharomyces pombe 58349 R-SPO-428123 https://reactome.org/PathwayBrowser/#/R-SPO-428123 KDSR reduces 3-ketosphingoid IEA Schizosaccharomyces pombe 58349 R-SPO-4419979 https://reactome.org/PathwayBrowser/#/R-SPO-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Schizosaccharomyces pombe 58349 R-SPO-469659 https://reactome.org/PathwayBrowser/#/R-SPO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 58349 R-SPO-508040 https://reactome.org/PathwayBrowser/#/R-SPO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Schizosaccharomyces pombe 58349 R-SPO-5419165 https://reactome.org/PathwayBrowser/#/R-SPO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Schizosaccharomyces pombe 58349 R-SPO-548831 https://reactome.org/PathwayBrowser/#/R-SPO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Schizosaccharomyces pombe 58349 R-SPO-5615668 https://reactome.org/PathwayBrowser/#/R-SPO-5615668 AKR1C3 reduces atRAL to atROL IEA Schizosaccharomyces pombe 58349 R-SPO-5652172 https://reactome.org/PathwayBrowser/#/R-SPO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Schizosaccharomyces pombe 58349 R-SPO-5661256 https://reactome.org/PathwayBrowser/#/R-SPO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Schizosaccharomyces pombe 58349 R-SPO-5692232 https://reactome.org/PathwayBrowser/#/R-SPO-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Schizosaccharomyces pombe 58349 R-SPO-5696822 https://reactome.org/PathwayBrowser/#/R-SPO-5696822 AKR1B15 reduces EST17b to E1 IEA Schizosaccharomyces pombe 58349 R-SPO-6783955 https://reactome.org/PathwayBrowser/#/R-SPO-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 58349 R-SPO-6807053 https://reactome.org/PathwayBrowser/#/R-SPO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Schizosaccharomyces pombe 58349 R-SPO-70377 https://reactome.org/PathwayBrowser/#/R-SPO-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Schizosaccharomyces pombe 58349 R-SPO-70938 https://reactome.org/PathwayBrowser/#/R-SPO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Schizosaccharomyces pombe 58349 R-SPO-71299 https://reactome.org/PathwayBrowser/#/R-SPO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 58349 R-SPO-71682 https://reactome.org/PathwayBrowser/#/R-SPO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 58349 R-SPO-804969 https://reactome.org/PathwayBrowser/#/R-SPO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Schizosaccharomyces pombe 58349 R-SPO-8862137 https://reactome.org/PathwayBrowser/#/R-SPO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Schizosaccharomyces pombe 58349 R-SPO-8862152 https://reactome.org/PathwayBrowser/#/R-SPO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Schizosaccharomyces pombe 58349 R-SPO-8952873 https://reactome.org/PathwayBrowser/#/R-SPO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Schizosaccharomyces pombe 58349 R-SPO-9705713 https://reactome.org/PathwayBrowser/#/R-SPO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 58349 R-SPO-9705714 https://reactome.org/PathwayBrowser/#/R-SPO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 58349 R-SPO-9709098 https://reactome.org/PathwayBrowser/#/R-SPO-9709098 DHFR dimer reduces FOLA to DHF IEA Schizosaccharomyces pombe 58349 R-SPO-9758682 https://reactome.org/PathwayBrowser/#/R-SPO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Schizosaccharomyces pombe 58349 R-SPO-9759259 https://reactome.org/PathwayBrowser/#/R-SPO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Schizosaccharomyces pombe 58349 R-SSC-1222376 https://reactome.org/PathwayBrowser/#/R-SSC-1222376 NOX2 generates superoxide from oxygen IEA Sus scrofa 58349 R-SSC-1475414 https://reactome.org/PathwayBrowser/#/R-SSC-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Sus scrofa 58349 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 58349 R-SSC-1497869 https://reactome.org/PathwayBrowser/#/R-SSC-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Sus scrofa 58349 R-SSC-156526 https://reactome.org/PathwayBrowser/#/R-SSC-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Sus scrofa 58349 R-SSC-1655453 https://reactome.org/PathwayBrowser/#/R-SSC-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Sus scrofa 58349 R-SSC-189384 https://reactome.org/PathwayBrowser/#/R-SSC-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Sus scrofa 58349 R-SSC-189398 https://reactome.org/PathwayBrowser/#/R-SSC-189398 HMOX1 dimer, HMOX2 cleave heme IEA Sus scrofa 58349 R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 58349 R-SSC-191352 https://reactome.org/PathwayBrowser/#/R-SSC-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Sus scrofa 58349 R-SSC-191402 https://reactome.org/PathwayBrowser/#/R-SSC-191402 Reduction of presqualene diphosphate to form squalene IEA Sus scrofa 58349 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 58349 R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 58349 R-SSC-191999 https://reactome.org/PathwayBrowser/#/R-SSC-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Sus scrofa 58349 R-SSC-192033 https://reactome.org/PathwayBrowser/#/R-SSC-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Sus scrofa 58349 R-SSC-192036 https://reactome.org/PathwayBrowser/#/R-SSC-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Sus scrofa 58349 R-SSC-192042 https://reactome.org/PathwayBrowser/#/R-SSC-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 58349 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 58349 R-SSC-192054 https://reactome.org/PathwayBrowser/#/R-SSC-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Sus scrofa 58349 R-SSC-192061 https://reactome.org/PathwayBrowser/#/R-SSC-192061 CYP46A1 24-hydroxylates CHOL IEA Sus scrofa 58349 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 58349 R-SSC-192067 https://reactome.org/PathwayBrowser/#/R-SSC-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Sus scrofa 58349 R-SSC-192123 https://reactome.org/PathwayBrowser/#/R-SSC-192123 CYP27A1 27-hydroxylates CHOL IEA Sus scrofa 58349 R-SSC-192157 https://reactome.org/PathwayBrowser/#/R-SSC-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Sus scrofa 58349 R-SSC-192160 https://reactome.org/PathwayBrowser/#/R-SSC-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Sus scrofa 58349 R-SSC-192178 https://reactome.org/PathwayBrowser/#/R-SSC-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Sus scrofa 58349 R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 58349 R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 58349 R-SSC-193064 https://reactome.org/PathwayBrowser/#/R-SSC-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Sus scrofa 58349 R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 58349 R-SSC-193068 https://reactome.org/PathwayBrowser/#/R-SSC-193068 CYP17A1 17-hydroxylates PREG IEA Sus scrofa 58349 R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 58349 R-SSC-193072 https://reactome.org/PathwayBrowser/#/R-SSC-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Sus scrofa 58349 R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 58349 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 58349 R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 58349 R-SSC-193393 https://reactome.org/PathwayBrowser/#/R-SSC-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Sus scrofa 58349 R-SSC-193460 https://reactome.org/PathwayBrowser/#/R-SSC-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Sus scrofa 58349 R-SSC-193497 https://reactome.org/PathwayBrowser/#/R-SSC-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Sus scrofa 58349 R-SSC-193709 https://reactome.org/PathwayBrowser/#/R-SSC-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Sus scrofa 58349 R-SSC-193713 https://reactome.org/PathwayBrowser/#/R-SSC-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Sus scrofa 58349 R-SSC-193719 https://reactome.org/PathwayBrowser/#/R-SSC-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 58349 R-SSC-193737 https://reactome.org/PathwayBrowser/#/R-SSC-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Sus scrofa 58349 R-SSC-193746 https://reactome.org/PathwayBrowser/#/R-SSC-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Sus scrofa 58349 R-SSC-193755 https://reactome.org/PathwayBrowser/#/R-SSC-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Sus scrofa 58349 R-SSC-193758 https://reactome.org/PathwayBrowser/#/R-SSC-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Sus scrofa 58349 R-SSC-193780 https://reactome.org/PathwayBrowser/#/R-SSC-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Sus scrofa 58349 R-SSC-193781 https://reactome.org/PathwayBrowser/#/R-SSC-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Sus scrofa 58349 R-SSC-193787 https://reactome.org/PathwayBrowser/#/R-SSC-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Sus scrofa 58349 R-SSC-193792 https://reactome.org/PathwayBrowser/#/R-SSC-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Sus scrofa 58349 R-SSC-193800 https://reactome.org/PathwayBrowser/#/R-SSC-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Sus scrofa 58349 R-SSC-193821 https://reactome.org/PathwayBrowser/#/R-SSC-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Sus scrofa 58349 R-SSC-193824 https://reactome.org/PathwayBrowser/#/R-SSC-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Sus scrofa 58349 R-SSC-193841 https://reactome.org/PathwayBrowser/#/R-SSC-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Sus scrofa 58349 R-SSC-193845 https://reactome.org/PathwayBrowser/#/R-SSC-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Sus scrofa 58349 R-SSC-193964 https://reactome.org/PathwayBrowser/#/R-SSC-193964 CYP21A2 21-hydroxylates PROG IEA Sus scrofa 58349 R-SSC-193965 https://reactome.org/PathwayBrowser/#/R-SSC-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Sus scrofa 58349 R-SSC-193981 https://reactome.org/PathwayBrowser/#/R-SSC-193981 CYP21A2 oxidises 17HPROG IEA Sus scrofa 58349 R-SSC-193995 https://reactome.org/PathwayBrowser/#/R-SSC-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Sus scrofa 58349 R-SSC-193997 https://reactome.org/PathwayBrowser/#/R-SSC-193997 CYP11B1 oxidises 11DCORT IEA Sus scrofa 58349 R-SSC-194017 https://reactome.org/PathwayBrowser/#/R-SSC-194017 CYP11B2 oxidises 11DCORST to CORST IEA Sus scrofa 58349 R-SSC-194023 https://reactome.org/PathwayBrowser/#/R-SSC-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Sus scrofa 58349 R-SSC-194632 https://reactome.org/PathwayBrowser/#/R-SSC-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Sus scrofa 58349 R-SSC-194641 https://reactome.org/PathwayBrowser/#/R-SSC-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 58349 R-SSC-194669 https://reactome.org/PathwayBrowser/#/R-SSC-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 58349 R-SSC-194678 https://reactome.org/PathwayBrowser/#/R-SSC-194678 CYP51A1 demethylates LNSOL IEA Sus scrofa 58349 R-SSC-194689 https://reactome.org/PathwayBrowser/#/R-SSC-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 58349 R-SSC-194698 https://reactome.org/PathwayBrowser/#/R-SSC-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Sus scrofa 58349 R-SSC-195664 https://reactome.org/PathwayBrowser/#/R-SSC-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Sus scrofa 58349 R-SSC-196060 https://reactome.org/PathwayBrowser/#/R-SSC-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Sus scrofa 58349 R-SSC-196402 https://reactome.org/PathwayBrowser/#/R-SSC-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Sus scrofa 58349 R-SSC-196417 https://reactome.org/PathwayBrowser/#/R-SSC-196417 Reduction of desmosterol to cholesterol IEA Sus scrofa 58349 R-SSC-197198 https://reactome.org/PathwayBrowser/#/R-SSC-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Sus scrofa 58349 R-SSC-197963 https://reactome.org/PathwayBrowser/#/R-SSC-197963 DHFR2 reduces FOLA to DHF IEA Sus scrofa 58349 R-SSC-197972 https://reactome.org/PathwayBrowser/#/R-SSC-197972 DHF is reduced to tetrahydrofolate (THF) IEA Sus scrofa 58349 R-SSC-200644 https://reactome.org/PathwayBrowser/#/R-SSC-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Sus scrofa 58349 R-SSC-200676 https://reactome.org/PathwayBrowser/#/R-SSC-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Sus scrofa 58349 R-SSC-200718 https://reactome.org/PathwayBrowser/#/R-SSC-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Sus scrofa 58349 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 58349 R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 58349 R-SSC-209772 https://reactome.org/PathwayBrowser/#/R-SSC-209772 Thyroxine is deiodinated to triiodothyronine IEA Sus scrofa 58349 R-SSC-209845 https://reactome.org/PathwayBrowser/#/R-SSC-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Sus scrofa 58349 R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 58349 R-SSC-211873 https://reactome.org/PathwayBrowser/#/R-SSC-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Sus scrofa 58349 R-SSC-211923 https://reactome.org/PathwayBrowser/#/R-SSC-211923 CYP26C1 4-hydroxylates 9cRA IEA Sus scrofa 58349 R-SSC-211950 https://reactome.org/PathwayBrowser/#/R-SSC-211950 CYP24A1 24-hydroxylates CTL IEA Sus scrofa 58349 R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 58349 R-SSC-2161549 https://reactome.org/PathwayBrowser/#/R-SSC-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Sus scrofa 58349 R-SSC-2161614 https://reactome.org/PathwayBrowser/#/R-SSC-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Sus scrofa 58349 R-SSC-2161617 https://reactome.org/PathwayBrowser/#/R-SSC-2161617 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 TAS Sus scrofa 58349 R-SSC-2161651 https://reactome.org/PathwayBrowser/#/R-SSC-2161651 PGE2 is converted to PGF2a by CBR1 IEA Sus scrofa 58349 R-SSC-2161745 https://reactome.org/PathwayBrowser/#/R-SSC-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Sus scrofa 58349 R-SSC-2161792 https://reactome.org/PathwayBrowser/#/R-SSC-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Sus scrofa 58349 R-SSC-2161847 https://reactome.org/PathwayBrowser/#/R-SSC-2161847 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 TAS Sus scrofa 58349 R-SSC-2161890 https://reactome.org/PathwayBrowser/#/R-SSC-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Sus scrofa 58349 R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Sus scrofa 58349 R-SSC-2161951 https://reactome.org/PathwayBrowser/#/R-SSC-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Sus scrofa 58349 R-SSC-2395517 https://reactome.org/PathwayBrowser/#/R-SSC-2395517 NADPH transfers electrons to FDXR IEA Sus scrofa 58349 R-SSC-2464822 https://reactome.org/PathwayBrowser/#/R-SSC-2464822 RDH12 reduces atRAL to atROL IEA Sus scrofa 58349 R-SSC-2465940 https://reactome.org/PathwayBrowser/#/R-SSC-2465940 atRAL is reduced to atROL IEA Sus scrofa 58349 R-SSC-2855252 https://reactome.org/PathwayBrowser/#/R-SSC-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Sus scrofa 58349 R-SSC-3149518 https://reactome.org/PathwayBrowser/#/R-SSC-3149518 MTRR reduces cob(II)alamin to meCbl IEA Sus scrofa 58349 R-SSC-3149519 https://reactome.org/PathwayBrowser/#/R-SSC-3149519 MMACHC decyanates CNCbl IEA Sus scrofa 58349 R-SSC-3323079 https://reactome.org/PathwayBrowser/#/R-SSC-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 58349 R-SSC-350869 https://reactome.org/PathwayBrowser/#/R-SSC-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Sus scrofa 58349 R-SSC-389540 https://reactome.org/PathwayBrowser/#/R-SSC-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 58349 R-SSC-390425 https://reactome.org/PathwayBrowser/#/R-SSC-390425 FAR1 reduces PalmCoA to HXOL IEA Sus scrofa 58349 R-SSC-390438 https://reactome.org/PathwayBrowser/#/R-SSC-390438 FAR2 reduces PalmCoA to HXOL IEA Sus scrofa 58349 R-SSC-418436 https://reactome.org/PathwayBrowser/#/R-SSC-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Sus scrofa 58349 R-SSC-428123 https://reactome.org/PathwayBrowser/#/R-SSC-428123 KDSR reduces 3-ketosphingoid IEA Sus scrofa 58349 R-SSC-4419979 https://reactome.org/PathwayBrowser/#/R-SSC-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Sus scrofa 58349 R-SSC-450984 https://reactome.org/PathwayBrowser/#/R-SSC-450984 IDH2 dimer decarboxylates isocitrate IEA Sus scrofa 58349 R-SSC-469659 https://reactome.org/PathwayBrowser/#/R-SSC-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Sus scrofa 58349 R-SSC-508040 https://reactome.org/PathwayBrowser/#/R-SSC-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Sus scrofa 58349 R-SSC-514604 https://reactome.org/PathwayBrowser/#/R-SSC-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Sus scrofa 58349 R-SSC-5218841 https://reactome.org/PathwayBrowser/#/R-SSC-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Sus scrofa 58349 R-SSC-5340226 https://reactome.org/PathwayBrowser/#/R-SSC-5340226 CYGB dioxygenates NO IEA Sus scrofa 58349 R-SSC-5362525 https://reactome.org/PathwayBrowser/#/R-SSC-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Sus scrofa 58349 R-SSC-5419165 https://reactome.org/PathwayBrowser/#/R-SSC-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Sus scrofa 58349 R-SSC-5423637 https://reactome.org/PathwayBrowser/#/R-SSC-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Sus scrofa 58349 R-SSC-5423647 https://reactome.org/PathwayBrowser/#/R-SSC-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Sus scrofa 58349 R-SSC-5423664 https://reactome.org/PathwayBrowser/#/R-SSC-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Sus scrofa 58349 R-SSC-5423672 https://reactome.org/PathwayBrowser/#/R-SSC-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Sus scrofa 58349 R-SSC-5423678 https://reactome.org/PathwayBrowser/#/R-SSC-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Sus scrofa 58349 R-SSC-548818 https://reactome.org/PathwayBrowser/#/R-SSC-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Sus scrofa 58349 R-SSC-548831 https://reactome.org/PathwayBrowser/#/R-SSC-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Sus scrofa 58349 R-SSC-5602295 https://reactome.org/PathwayBrowser/#/R-SSC-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Sus scrofa 58349 R-SSC-5615668 https://reactome.org/PathwayBrowser/#/R-SSC-5615668 AKR1C3 reduces atRAL to atROL IEA Sus scrofa 58349 R-SSC-5652172 https://reactome.org/PathwayBrowser/#/R-SSC-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Sus scrofa 58349 R-SSC-5661240 https://reactome.org/PathwayBrowser/#/R-SSC-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Sus scrofa 58349 R-SSC-5661256 https://reactome.org/PathwayBrowser/#/R-SSC-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Sus scrofa 58349 R-SSC-5668629 https://reactome.org/PathwayBrowser/#/R-SSC-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Sus scrofa 58349 R-SSC-5668718 https://reactome.org/PathwayBrowser/#/R-SSC-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 58349 R-SSC-5668731 https://reactome.org/PathwayBrowser/#/R-SSC-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 58349 R-SSC-5692232 https://reactome.org/PathwayBrowser/#/R-SSC-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Sus scrofa 58349 R-SSC-5692283 https://reactome.org/PathwayBrowser/#/R-SSC-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Sus scrofa 58349 R-SSC-5693390 https://reactome.org/PathwayBrowser/#/R-SSC-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Sus scrofa 58349 R-SSC-6783955 https://reactome.org/PathwayBrowser/#/R-SSC-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 58349 R-SSC-6786239 https://reactome.org/PathwayBrowser/#/R-SSC-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Sus scrofa 58349 R-SSC-6787642 https://reactome.org/PathwayBrowser/#/R-SSC-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Sus scrofa 58349 R-SSC-6789092 https://reactome.org/PathwayBrowser/#/R-SSC-6789092 NOX2 generates superoxide anion from oxygen IEA Sus scrofa 58349 R-SSC-6799722 https://reactome.org/PathwayBrowser/#/R-SSC-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Sus scrofa 58349 R-SSC-6807053 https://reactome.org/PathwayBrowser/#/R-SSC-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Sus scrofa 58349 R-SSC-6807055 https://reactome.org/PathwayBrowser/#/R-SSC-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Sus scrofa 58349 R-SSC-6807064 https://reactome.org/PathwayBrowser/#/R-SSC-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Sus scrofa 58349 R-SSC-6807557 https://reactome.org/PathwayBrowser/#/R-SSC-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Sus scrofa 58349 R-SSC-6808487 https://reactome.org/PathwayBrowser/#/R-SSC-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 58349 R-SSC-6808496 https://reactome.org/PathwayBrowser/#/R-SSC-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 58349 R-SSC-70377 https://reactome.org/PathwayBrowser/#/R-SSC-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Sus scrofa 58349 R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Sus scrofa 58349 R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Sus scrofa 58349 R-SSC-70938 https://reactome.org/PathwayBrowser/#/R-SSC-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Sus scrofa 58349 R-SSC-71200 https://reactome.org/PathwayBrowser/#/R-SSC-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Sus scrofa 58349 R-SSC-71299 https://reactome.org/PathwayBrowser/#/R-SSC-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Sus scrofa 58349 R-SSC-71682 https://reactome.org/PathwayBrowser/#/R-SSC-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 58349 R-SSC-73585 https://reactome.org/PathwayBrowser/#/R-SSC-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Sus scrofa 58349 R-SSC-73616 https://reactome.org/PathwayBrowser/#/R-SSC-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Sus scrofa 58349 R-SSC-74872 https://reactome.org/PathwayBrowser/#/R-SSC-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Sus scrofa 58349 R-SSC-75872 https://reactome.org/PathwayBrowser/#/R-SSC-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Sus scrofa 58349 R-SSC-75883 https://reactome.org/PathwayBrowser/#/R-SSC-75883 DHRS7B reduces GO3P to HXDG3P IEA Sus scrofa 58349 R-SSC-804969 https://reactome.org/PathwayBrowser/#/R-SSC-804969 HSD17B1 hydrogenates E1 to EST17b IEA Sus scrofa 58349 R-SSC-8862137 https://reactome.org/PathwayBrowser/#/R-SSC-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Sus scrofa 58349 R-SSC-8862152 https://reactome.org/PathwayBrowser/#/R-SSC-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Sus scrofa 58349 R-SSC-8865107 https://reactome.org/PathwayBrowser/#/R-SSC-8865107 MICAL1 produces NADP+, H2O2 IEA Sus scrofa 58349 R-SSC-8937419 https://reactome.org/PathwayBrowser/#/R-SSC-8937419 CBR3 reduces DOX to DOXOL IEA Sus scrofa 58349 R-SSC-8952873 https://reactome.org/PathwayBrowser/#/R-SSC-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Sus scrofa 58349 R-SSC-8955030 https://reactome.org/PathwayBrowser/#/R-SSC-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Sus scrofa 58349 R-SSC-9012036 https://reactome.org/PathwayBrowser/#/R-SSC-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Sus scrofa 58349 R-SSC-9012349 https://reactome.org/PathwayBrowser/#/R-SSC-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Sus scrofa 58349 R-SSC-9020255 https://reactome.org/PathwayBrowser/#/R-SSC-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Sus scrofa 58349 R-SSC-9020256 https://reactome.org/PathwayBrowser/#/R-SSC-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Sus scrofa 58349 R-SSC-9020262 https://reactome.org/PathwayBrowser/#/R-SSC-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Sus scrofa 58349 R-SSC-9020277 https://reactome.org/PathwayBrowser/#/R-SSC-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Sus scrofa 58349 R-SSC-9020278 https://reactome.org/PathwayBrowser/#/R-SSC-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Sus scrofa 58349 R-SSC-9024881 https://reactome.org/PathwayBrowser/#/R-SSC-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Sus scrofa 58349 R-SSC-9024983 https://reactome.org/PathwayBrowser/#/R-SSC-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Sus scrofa 58349 R-SSC-9025995 https://reactome.org/PathwayBrowser/#/R-SSC-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Sus scrofa 58349 R-SSC-9025999 https://reactome.org/PathwayBrowser/#/R-SSC-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Sus scrofa 58349 R-SSC-9026007 https://reactome.org/PathwayBrowser/#/R-SSC-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Sus scrofa 58349 R-SSC-9027043 https://reactome.org/PathwayBrowser/#/R-SSC-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Sus scrofa 58349 R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 58349 R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 58349 R-SSC-9037761 https://reactome.org/PathwayBrowser/#/R-SSC-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Sus scrofa 58349 R-SSC-917811 https://reactome.org/PathwayBrowser/#/R-SSC-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Sus scrofa 58349 R-SSC-9705713 https://reactome.org/PathwayBrowser/#/R-SSC-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Sus scrofa 58349 R-SSC-9705714 https://reactome.org/PathwayBrowser/#/R-SSC-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Sus scrofa 58349 R-SSC-9709098 https://reactome.org/PathwayBrowser/#/R-SSC-9709098 DHFR dimer reduces FOLA to DHF IEA Sus scrofa 58349 R-SSC-9753285 https://reactome.org/PathwayBrowser/#/R-SSC-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Sus scrofa 58349 R-SSC-9755937 https://reactome.org/PathwayBrowser/#/R-SSC-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Sus scrofa 58349 R-SSC-9756138 https://reactome.org/PathwayBrowser/#/R-SSC-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Sus scrofa 58349 R-SSC-9756162 https://reactome.org/PathwayBrowser/#/R-SSC-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Sus scrofa 58349 R-SSC-9756169 https://reactome.org/PathwayBrowser/#/R-SSC-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Sus scrofa 58349 R-SSC-9756180 https://reactome.org/PathwayBrowser/#/R-SSC-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Sus scrofa 58349 R-SSC-975629 https://reactome.org/PathwayBrowser/#/R-SSC-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Sus scrofa 58349 R-SSC-9757706 https://reactome.org/PathwayBrowser/#/R-SSC-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Sus scrofa 58349 R-SSC-9758682 https://reactome.org/PathwayBrowser/#/R-SSC-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Sus scrofa 58349 R-SSC-9759259 https://reactome.org/PathwayBrowser/#/R-SSC-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Sus scrofa 58349 R-XTR-1222376 https://reactome.org/PathwayBrowser/#/R-XTR-1222376 NOX2 generates superoxide from oxygen IEA Xenopus tropicalis 58349 R-XTR-1475414 https://reactome.org/PathwayBrowser/#/R-XTR-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Xenopus tropicalis 58349 R-XTR-1497869 https://reactome.org/PathwayBrowser/#/R-XTR-1497869 Salvage - Sepiapterin is reduced to BH2 IEA Xenopus tropicalis 58349 R-XTR-156526 https://reactome.org/PathwayBrowser/#/R-XTR-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 58349 R-XTR-1655453 https://reactome.org/PathwayBrowser/#/R-XTR-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Xenopus tropicalis 58349 R-XTR-189384 https://reactome.org/PathwayBrowser/#/R-XTR-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Xenopus tropicalis 58349 R-XTR-189398 https://reactome.org/PathwayBrowser/#/R-XTR-189398 HMOX1 dimer, HMOX2 cleave heme IEA Xenopus tropicalis 58349 R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 58349 R-XTR-191352 https://reactome.org/PathwayBrowser/#/R-XTR-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Xenopus tropicalis 58349 R-XTR-191402 https://reactome.org/PathwayBrowser/#/R-XTR-191402 Reduction of presqualene diphosphate to form squalene IEA Xenopus tropicalis 58349 R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 58349 R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 58349 R-XTR-192033 https://reactome.org/PathwayBrowser/#/R-XTR-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Xenopus tropicalis 58349 R-XTR-192036 https://reactome.org/PathwayBrowser/#/R-XTR-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Xenopus tropicalis 58349 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 58349 R-XTR-192061 https://reactome.org/PathwayBrowser/#/R-XTR-192061 CYP46A1 24-hydroxylates CHOL IEA Xenopus tropicalis 58349 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 58349 R-XTR-192067 https://reactome.org/PathwayBrowser/#/R-XTR-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Xenopus tropicalis 58349 R-XTR-192157 https://reactome.org/PathwayBrowser/#/R-XTR-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Xenopus tropicalis 58349 R-XTR-192160 https://reactome.org/PathwayBrowser/#/R-XTR-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Xenopus tropicalis 58349 R-XTR-192178 https://reactome.org/PathwayBrowser/#/R-XTR-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Xenopus tropicalis 58349 R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 58349 R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 58349 R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 58349 R-XTR-193068 https://reactome.org/PathwayBrowser/#/R-XTR-193068 CYP17A1 17-hydroxylates PREG IEA Xenopus tropicalis 58349 R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 58349 R-XTR-193072 https://reactome.org/PathwayBrowser/#/R-XTR-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Xenopus tropicalis 58349 R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 58349 R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 58349 R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 58349 R-XTR-193709 https://reactome.org/PathwayBrowser/#/R-XTR-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Xenopus tropicalis 58349 R-XTR-193746 https://reactome.org/PathwayBrowser/#/R-XTR-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 58349 R-XTR-193755 https://reactome.org/PathwayBrowser/#/R-XTR-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Xenopus tropicalis 58349 R-XTR-193758 https://reactome.org/PathwayBrowser/#/R-XTR-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Xenopus tropicalis 58349 R-XTR-193781 https://reactome.org/PathwayBrowser/#/R-XTR-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Xenopus tropicalis 58349 R-XTR-193800 https://reactome.org/PathwayBrowser/#/R-XTR-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Xenopus tropicalis 58349 R-XTR-193821 https://reactome.org/PathwayBrowser/#/R-XTR-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Xenopus tropicalis 58349 R-XTR-193824 https://reactome.org/PathwayBrowser/#/R-XTR-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Xenopus tropicalis 58349 R-XTR-193841 https://reactome.org/PathwayBrowser/#/R-XTR-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Xenopus tropicalis 58349 R-XTR-193845 https://reactome.org/PathwayBrowser/#/R-XTR-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Xenopus tropicalis 58349 R-XTR-193965 https://reactome.org/PathwayBrowser/#/R-XTR-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Xenopus tropicalis 58349 R-XTR-193995 https://reactome.org/PathwayBrowser/#/R-XTR-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Xenopus tropicalis 58349 R-XTR-193997 https://reactome.org/PathwayBrowser/#/R-XTR-193997 CYP11B1 oxidises 11DCORT IEA Xenopus tropicalis 58349 R-XTR-194017 https://reactome.org/PathwayBrowser/#/R-XTR-194017 CYP11B2 oxidises 11DCORST to CORST IEA Xenopus tropicalis 58349 R-XTR-194023 https://reactome.org/PathwayBrowser/#/R-XTR-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Xenopus tropicalis 58349 R-XTR-194641 https://reactome.org/PathwayBrowser/#/R-XTR-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 58349 R-XTR-194669 https://reactome.org/PathwayBrowser/#/R-XTR-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 58349 R-XTR-195664 https://reactome.org/PathwayBrowser/#/R-XTR-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Xenopus tropicalis 58349 R-XTR-196060 https://reactome.org/PathwayBrowser/#/R-XTR-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Xenopus tropicalis 58349 R-XTR-196402 https://reactome.org/PathwayBrowser/#/R-XTR-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Xenopus tropicalis 58349 R-XTR-196417 https://reactome.org/PathwayBrowser/#/R-XTR-196417 Reduction of desmosterol to cholesterol IEA Xenopus tropicalis 58349 R-XTR-197198 https://reactome.org/PathwayBrowser/#/R-XTR-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 58349 R-XTR-200644 https://reactome.org/PathwayBrowser/#/R-XTR-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Xenopus tropicalis 58349 R-XTR-200676 https://reactome.org/PathwayBrowser/#/R-XTR-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Xenopus tropicalis 58349 R-XTR-200718 https://reactome.org/PathwayBrowser/#/R-XTR-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Xenopus tropicalis 58349 R-XTR-209845 https://reactome.org/PathwayBrowser/#/R-XTR-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Xenopus tropicalis 58349 R-XTR-211873 https://reactome.org/PathwayBrowser/#/R-XTR-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Xenopus tropicalis 58349 R-XTR-211923 https://reactome.org/PathwayBrowser/#/R-XTR-211923 CYP26C1 4-hydroxylates 9cRA IEA Xenopus tropicalis 58349 R-XTR-2161549 https://reactome.org/PathwayBrowser/#/R-XTR-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Xenopus tropicalis 58349 R-XTR-2161614 https://reactome.org/PathwayBrowser/#/R-XTR-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Xenopus tropicalis 58349 R-XTR-2161651 https://reactome.org/PathwayBrowser/#/R-XTR-2161651 PGE2 is converted to PGF2a by CBR1 IEA Xenopus tropicalis 58349 R-XTR-2161745 https://reactome.org/PathwayBrowser/#/R-XTR-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 58349 R-XTR-2161792 https://reactome.org/PathwayBrowser/#/R-XTR-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 58349 R-XTR-2161890 https://reactome.org/PathwayBrowser/#/R-XTR-2161890 Arachidonic acid is epoxidated to 5,6-EET by CYP(4) IEA Xenopus tropicalis 58349 R-XTR-2161899 https://reactome.org/PathwayBrowser/#/R-XTR-2161899 Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) IEA Xenopus tropicalis 58349 R-XTR-2161951 https://reactome.org/PathwayBrowser/#/R-XTR-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Xenopus tropicalis 58349 R-XTR-2395517 https://reactome.org/PathwayBrowser/#/R-XTR-2395517 NADPH transfers electrons to FDXR IEA Xenopus tropicalis 58349 R-XTR-2465940 https://reactome.org/PathwayBrowser/#/R-XTR-2465940 atRAL is reduced to atROL IEA Xenopus tropicalis 58349 R-XTR-2855252 https://reactome.org/PathwayBrowser/#/R-XTR-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Xenopus tropicalis 58349 R-XTR-3149519 https://reactome.org/PathwayBrowser/#/R-XTR-3149519 MMACHC decyanates CNCbl IEA Xenopus tropicalis 58349 R-XTR-3323079 https://reactome.org/PathwayBrowser/#/R-XTR-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 58349 R-XTR-389540 https://reactome.org/PathwayBrowser/#/R-XTR-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 58349 R-XTR-428123 https://reactome.org/PathwayBrowser/#/R-XTR-428123 KDSR reduces 3-ketosphingoid IEA Xenopus tropicalis 58349 R-XTR-4419979 https://reactome.org/PathwayBrowser/#/R-XTR-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Xenopus tropicalis 58349 R-XTR-450971 https://reactome.org/PathwayBrowser/#/R-XTR-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Xenopus tropicalis 58349 R-XTR-450984 https://reactome.org/PathwayBrowser/#/R-XTR-450984 IDH2 dimer decarboxylates isocitrate IEA Xenopus tropicalis 58349 R-XTR-469659 https://reactome.org/PathwayBrowser/#/R-XTR-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 58349 R-XTR-508040 https://reactome.org/PathwayBrowser/#/R-XTR-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Xenopus tropicalis 58349 R-XTR-514604 https://reactome.org/PathwayBrowser/#/R-XTR-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Xenopus tropicalis 58349 R-XTR-5218841 https://reactome.org/PathwayBrowser/#/R-XTR-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Xenopus tropicalis 58349 R-XTR-5340226 https://reactome.org/PathwayBrowser/#/R-XTR-5340226 CYGB dioxygenates NO IEA Xenopus tropicalis 58349 R-XTR-5362525 https://reactome.org/PathwayBrowser/#/R-XTR-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Xenopus tropicalis 58349 R-XTR-5419165 https://reactome.org/PathwayBrowser/#/R-XTR-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Xenopus tropicalis 58349 R-XTR-5423647 https://reactome.org/PathwayBrowser/#/R-XTR-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Xenopus tropicalis 58349 R-XTR-5423664 https://reactome.org/PathwayBrowser/#/R-XTR-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Xenopus tropicalis 58349 R-XTR-5423672 https://reactome.org/PathwayBrowser/#/R-XTR-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Xenopus tropicalis 58349 R-XTR-548818 https://reactome.org/PathwayBrowser/#/R-XTR-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Xenopus tropicalis 58349 R-XTR-548831 https://reactome.org/PathwayBrowser/#/R-XTR-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Xenopus tropicalis 58349 R-XTR-5602295 https://reactome.org/PathwayBrowser/#/R-XTR-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Xenopus tropicalis 58349 R-XTR-5615668 https://reactome.org/PathwayBrowser/#/R-XTR-5615668 AKR1C3 reduces atRAL to atROL IEA Xenopus tropicalis 58349 R-XTR-5652172 https://reactome.org/PathwayBrowser/#/R-XTR-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Xenopus tropicalis 58349 R-XTR-5661240 https://reactome.org/PathwayBrowser/#/R-XTR-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Xenopus tropicalis 58349 R-XTR-5661256 https://reactome.org/PathwayBrowser/#/R-XTR-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Xenopus tropicalis 58349 R-XTR-5668629 https://reactome.org/PathwayBrowser/#/R-XTR-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Xenopus tropicalis 58349 R-XTR-5668718 https://reactome.org/PathwayBrowser/#/R-XTR-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 58349 R-XTR-5668731 https://reactome.org/PathwayBrowser/#/R-XTR-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 58349 R-XTR-5692232 https://reactome.org/PathwayBrowser/#/R-XTR-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Xenopus tropicalis 58349 R-XTR-5693390 https://reactome.org/PathwayBrowser/#/R-XTR-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Xenopus tropicalis 58349 R-XTR-5696822 https://reactome.org/PathwayBrowser/#/R-XTR-5696822 AKR1B15 reduces EST17b to E1 IEA Xenopus tropicalis 58349 R-XTR-6786239 https://reactome.org/PathwayBrowser/#/R-XTR-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Xenopus tropicalis 58349 R-XTR-6787642 https://reactome.org/PathwayBrowser/#/R-XTR-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Xenopus tropicalis 58349 R-XTR-6789092 https://reactome.org/PathwayBrowser/#/R-XTR-6789092 NOX2 generates superoxide anion from oxygen IEA Xenopus tropicalis 58349 R-XTR-6799722 https://reactome.org/PathwayBrowser/#/R-XTR-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Xenopus tropicalis 58349 R-XTR-6807053 https://reactome.org/PathwayBrowser/#/R-XTR-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Xenopus tropicalis 58349 R-XTR-6807055 https://reactome.org/PathwayBrowser/#/R-XTR-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Xenopus tropicalis 58349 R-XTR-6807064 https://reactome.org/PathwayBrowser/#/R-XTR-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Xenopus tropicalis 58349 R-XTR-6808487 https://reactome.org/PathwayBrowser/#/R-XTR-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 58349 R-XTR-6808496 https://reactome.org/PathwayBrowser/#/R-XTR-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 58349 R-XTR-6810594 https://reactome.org/PathwayBrowser/#/R-XTR-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 58349 R-XTR-70377 https://reactome.org/PathwayBrowser/#/R-XTR-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ IEA Xenopus tropicalis 58349 R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] IEA Xenopus tropicalis 58349 R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] IEA Xenopus tropicalis 58349 R-XTR-70938 https://reactome.org/PathwayBrowser/#/R-XTR-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Xenopus tropicalis 58349 R-XTR-71200 https://reactome.org/PathwayBrowser/#/R-XTR-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Xenopus tropicalis 58349 R-XTR-71682 https://reactome.org/PathwayBrowser/#/R-XTR-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 58349 R-XTR-73585 https://reactome.org/PathwayBrowser/#/R-XTR-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Xenopus tropicalis 58349 R-XTR-73616 https://reactome.org/PathwayBrowser/#/R-XTR-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Xenopus tropicalis 58349 R-XTR-74872 https://reactome.org/PathwayBrowser/#/R-XTR-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 58349 R-XTR-75872 https://reactome.org/PathwayBrowser/#/R-XTR-75872 acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O IEA Xenopus tropicalis 58349 R-XTR-75883 https://reactome.org/PathwayBrowser/#/R-XTR-75883 DHRS7B reduces GO3P to HXDG3P IEA Xenopus tropicalis 58349 R-XTR-804969 https://reactome.org/PathwayBrowser/#/R-XTR-804969 HSD17B1 hydrogenates E1 to EST17b IEA Xenopus tropicalis 58349 R-XTR-8862137 https://reactome.org/PathwayBrowser/#/R-XTR-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 58349 R-XTR-8862152 https://reactome.org/PathwayBrowser/#/R-XTR-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Xenopus tropicalis 58349 R-XTR-8865107 https://reactome.org/PathwayBrowser/#/R-XTR-8865107 MICAL1 produces NADP+, H2O2 IEA Xenopus tropicalis 58349 R-XTR-8937419 https://reactome.org/PathwayBrowser/#/R-XTR-8937419 CBR3 reduces DOX to DOXOL IEA Xenopus tropicalis 58349 R-XTR-8952873 https://reactome.org/PathwayBrowser/#/R-XTR-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Xenopus tropicalis 58349 R-XTR-8955030 https://reactome.org/PathwayBrowser/#/R-XTR-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 58349 R-XTR-9012349 https://reactome.org/PathwayBrowser/#/R-XTR-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 58349 R-XTR-9020255 https://reactome.org/PathwayBrowser/#/R-XTR-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Xenopus tropicalis 58349 R-XTR-9020256 https://reactome.org/PathwayBrowser/#/R-XTR-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Xenopus tropicalis 58349 R-XTR-9020277 https://reactome.org/PathwayBrowser/#/R-XTR-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Xenopus tropicalis 58349 R-XTR-9020278 https://reactome.org/PathwayBrowser/#/R-XTR-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Xenopus tropicalis 58349 R-XTR-9025995 https://reactome.org/PathwayBrowser/#/R-XTR-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Xenopus tropicalis 58349 R-XTR-9025999 https://reactome.org/PathwayBrowser/#/R-XTR-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Xenopus tropicalis 58349 R-XTR-9027043 https://reactome.org/PathwayBrowser/#/R-XTR-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Xenopus tropicalis 58349 R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 58349 R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 58349 R-XTR-917811 https://reactome.org/PathwayBrowser/#/R-XTR-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Xenopus tropicalis 58349 R-XTR-9705713 https://reactome.org/PathwayBrowser/#/R-XTR-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 58349 R-XTR-9705714 https://reactome.org/PathwayBrowser/#/R-XTR-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 58349 R-XTR-9753285 https://reactome.org/PathwayBrowser/#/R-XTR-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Xenopus tropicalis 58349 R-XTR-9755937 https://reactome.org/PathwayBrowser/#/R-XTR-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Xenopus tropicalis 58349 R-XTR-9756138 https://reactome.org/PathwayBrowser/#/R-XTR-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Xenopus tropicalis 58349 R-XTR-9756162 https://reactome.org/PathwayBrowser/#/R-XTR-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Xenopus tropicalis 58349 R-XTR-9756169 https://reactome.org/PathwayBrowser/#/R-XTR-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Xenopus tropicalis 58349 R-XTR-9756180 https://reactome.org/PathwayBrowser/#/R-XTR-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Xenopus tropicalis 58349 R-XTR-9757706 https://reactome.org/PathwayBrowser/#/R-XTR-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Xenopus tropicalis 58349 R-XTR-9758682 https://reactome.org/PathwayBrowser/#/R-XTR-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Xenopus tropicalis 58349 R-XTR-9759259 https://reactome.org/PathwayBrowser/#/R-XTR-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Xenopus tropicalis 58359 R-BTA-197271 https://reactome.org/PathwayBrowser/#/R-BTA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Bos taurus 58359 R-BTA-212614 https://reactome.org/PathwayBrowser/#/R-BTA-212614 Glutamine transport from astrocytes IEA Bos taurus 58359 R-BTA-212642 https://reactome.org/PathwayBrowser/#/R-BTA-212642 L-Glutamine transport into neurons IEA Bos taurus 58359 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 58359 R-BTA-352108 https://reactome.org/PathwayBrowser/#/R-BTA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Bos taurus 58359 R-BTA-352119 https://reactome.org/PathwayBrowser/#/R-BTA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Bos taurus 58359 R-BTA-352174 https://reactome.org/PathwayBrowser/#/R-BTA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Bos taurus 58359 R-BTA-352182 https://reactome.org/PathwayBrowser/#/R-BTA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Bos taurus 58359 R-BTA-352191 https://reactome.org/PathwayBrowser/#/R-BTA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Bos taurus 58359 R-BTA-352379 https://reactome.org/PathwayBrowser/#/R-BTA-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Bos taurus 58359 R-BTA-352385 https://reactome.org/PathwayBrowser/#/R-BTA-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Bos taurus 58359 R-BTA-375473 https://reactome.org/PathwayBrowser/#/R-BTA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Bos taurus 58359 R-BTA-449715 https://reactome.org/PathwayBrowser/#/R-BTA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Bos taurus 58359 R-BTA-504054 https://reactome.org/PathwayBrowser/#/R-BTA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Bos taurus 58359 R-BTA-70599 https://reactome.org/PathwayBrowser/#/R-BTA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Bos taurus 58359 R-BTA-70606 https://reactome.org/PathwayBrowser/#/R-BTA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Bos taurus 58359 R-BTA-70609 https://reactome.org/PathwayBrowser/#/R-BTA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Bos taurus 58359 R-BTA-73577 https://reactome.org/PathwayBrowser/#/R-BTA-73577 CAD hexamer transforms L-Gln to CAP IEA Bos taurus 58359 R-BTA-73647 https://reactome.org/PathwayBrowser/#/R-BTA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Bos taurus 58359 R-BTA-73792 https://reactome.org/PathwayBrowser/#/R-BTA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Bos taurus 58359 R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 58359 R-BTA-73815 https://reactome.org/PathwayBrowser/#/R-BTA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Bos taurus 58359 R-BTA-893616 https://reactome.org/PathwayBrowser/#/R-BTA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Bos taurus 58359 R-BTA-9748957 https://reactome.org/PathwayBrowser/#/R-BTA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Bos taurus 58359 R-CEL-197271 https://reactome.org/PathwayBrowser/#/R-CEL-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Caenorhabditis elegans 58359 R-CEL-352379 https://reactome.org/PathwayBrowser/#/R-CEL-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Caenorhabditis elegans 58359 R-CEL-352385 https://reactome.org/PathwayBrowser/#/R-CEL-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Caenorhabditis elegans 58359 R-CEL-449715 https://reactome.org/PathwayBrowser/#/R-CEL-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Caenorhabditis elegans 58359 R-CEL-504054 https://reactome.org/PathwayBrowser/#/R-CEL-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Caenorhabditis elegans 58359 R-CEL-70599 https://reactome.org/PathwayBrowser/#/R-CEL-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Caenorhabditis elegans 58359 R-CEL-70606 https://reactome.org/PathwayBrowser/#/R-CEL-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Caenorhabditis elegans 58359 R-CEL-70609 https://reactome.org/PathwayBrowser/#/R-CEL-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Caenorhabditis elegans 58359 R-CEL-73577 https://reactome.org/PathwayBrowser/#/R-CEL-73577 CAD hexamer transforms L-Gln to CAP IEA Caenorhabditis elegans 58359 R-CEL-73647 https://reactome.org/PathwayBrowser/#/R-CEL-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Caenorhabditis elegans 58359 R-CEL-73792 https://reactome.org/PathwayBrowser/#/R-CEL-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Caenorhabditis elegans 58359 R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 58359 R-CEL-73815 https://reactome.org/PathwayBrowser/#/R-CEL-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Caenorhabditis elegans 58359 R-CEL-893616 https://reactome.org/PathwayBrowser/#/R-CEL-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Caenorhabditis elegans 58359 R-CEL-9748957 https://reactome.org/PathwayBrowser/#/R-CEL-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Caenorhabditis elegans 58359 R-CFA-197271 https://reactome.org/PathwayBrowser/#/R-CFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Canis familiaris 58359 R-CFA-212614 https://reactome.org/PathwayBrowser/#/R-CFA-212614 Glutamine transport from astrocytes IEA Canis familiaris 58359 R-CFA-212642 https://reactome.org/PathwayBrowser/#/R-CFA-212642 L-Glutamine transport into neurons IEA Canis familiaris 58359 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 58359 R-CFA-352108 https://reactome.org/PathwayBrowser/#/R-CFA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Canis familiaris 58359 R-CFA-352119 https://reactome.org/PathwayBrowser/#/R-CFA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Canis familiaris 58359 R-CFA-352174 https://reactome.org/PathwayBrowser/#/R-CFA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Canis familiaris 58359 R-CFA-352182 https://reactome.org/PathwayBrowser/#/R-CFA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Canis familiaris 58359 R-CFA-352191 https://reactome.org/PathwayBrowser/#/R-CFA-352191 SLC7A8-mediated uptake of neutral amino acids IEA Canis familiaris 58359 R-CFA-352379 https://reactome.org/PathwayBrowser/#/R-CFA-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Canis familiaris 58359 R-CFA-352385 https://reactome.org/PathwayBrowser/#/R-CFA-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Canis familiaris 58359 R-CFA-375473 https://reactome.org/PathwayBrowser/#/R-CFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Canis familiaris 58359 R-CFA-449715 https://reactome.org/PathwayBrowser/#/R-CFA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Canis familiaris 58359 R-CFA-504054 https://reactome.org/PathwayBrowser/#/R-CFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Canis familiaris 58359 R-CFA-70599 https://reactome.org/PathwayBrowser/#/R-CFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Canis familiaris 58359 R-CFA-70606 https://reactome.org/PathwayBrowser/#/R-CFA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Canis familiaris 58359 R-CFA-70609 https://reactome.org/PathwayBrowser/#/R-CFA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Canis familiaris 58359 R-CFA-73577 https://reactome.org/PathwayBrowser/#/R-CFA-73577 CAD hexamer transforms L-Gln to CAP IEA Canis familiaris 58359 R-CFA-73647 https://reactome.org/PathwayBrowser/#/R-CFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Canis familiaris 58359 R-CFA-73792 https://reactome.org/PathwayBrowser/#/R-CFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Canis familiaris 58359 R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 58359 R-CFA-73815 https://reactome.org/PathwayBrowser/#/R-CFA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Canis familiaris 58359 R-CFA-893616 https://reactome.org/PathwayBrowser/#/R-CFA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Canis familiaris 58359 R-CFA-9748957 https://reactome.org/PathwayBrowser/#/R-CFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Canis familiaris 58359 R-DDI-197271 https://reactome.org/PathwayBrowser/#/R-DDI-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Dictyostelium discoideum 58359 R-DDI-449715 https://reactome.org/PathwayBrowser/#/R-DDI-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Dictyostelium discoideum 58359 R-DDI-504054 https://reactome.org/PathwayBrowser/#/R-DDI-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Dictyostelium discoideum 58359 R-DDI-70599 https://reactome.org/PathwayBrowser/#/R-DDI-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Dictyostelium discoideum 58359 R-DDI-73577 https://reactome.org/PathwayBrowser/#/R-DDI-73577 CAD hexamer transforms L-Gln to CAP IEA Dictyostelium discoideum 58359 R-DDI-73647 https://reactome.org/PathwayBrowser/#/R-DDI-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Dictyostelium discoideum 58359 R-DDI-73792 https://reactome.org/PathwayBrowser/#/R-DDI-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Dictyostelium discoideum 58359 R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 58359 R-DDI-893616 https://reactome.org/PathwayBrowser/#/R-DDI-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Dictyostelium discoideum 58359 R-DDI-9748957 https://reactome.org/PathwayBrowser/#/R-DDI-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Dictyostelium discoideum 58359 R-DME-197271 https://reactome.org/PathwayBrowser/#/R-DME-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Drosophila melanogaster 58359 R-DME-212614 https://reactome.org/PathwayBrowser/#/R-DME-212614 Glutamine transport from astrocytes IEA Drosophila melanogaster 58359 R-DME-212642 https://reactome.org/PathwayBrowser/#/R-DME-212642 L-Glutamine transport into neurons IEA Drosophila melanogaster 58359 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 58359 R-DME-352108 https://reactome.org/PathwayBrowser/#/R-DME-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 58359 R-DME-352119 https://reactome.org/PathwayBrowser/#/R-DME-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 58359 R-DME-352174 https://reactome.org/PathwayBrowser/#/R-DME-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Drosophila melanogaster 58359 R-DME-352182 https://reactome.org/PathwayBrowser/#/R-DME-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Drosophila melanogaster 58359 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster 58359 R-DME-352379 https://reactome.org/PathwayBrowser/#/R-DME-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Drosophila melanogaster 58359 R-DME-352385 https://reactome.org/PathwayBrowser/#/R-DME-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Drosophila melanogaster 58359 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 58359 R-DME-449715 https://reactome.org/PathwayBrowser/#/R-DME-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Drosophila melanogaster 58359 R-DME-504054 https://reactome.org/PathwayBrowser/#/R-DME-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Drosophila melanogaster 58359 R-DME-70606 https://reactome.org/PathwayBrowser/#/R-DME-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Drosophila melanogaster 58359 R-DME-70609 https://reactome.org/PathwayBrowser/#/R-DME-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Drosophila melanogaster 58359 R-DME-73577 https://reactome.org/PathwayBrowser/#/R-DME-73577 CAD hexamer transforms L-Gln to CAP IEA Drosophila melanogaster 58359 R-DME-73647 https://reactome.org/PathwayBrowser/#/R-DME-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Drosophila melanogaster 58359 R-DME-73792 https://reactome.org/PathwayBrowser/#/R-DME-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Drosophila melanogaster 58359 R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 58359 R-DME-73815 https://reactome.org/PathwayBrowser/#/R-DME-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Drosophila melanogaster 58359 R-DME-893616 https://reactome.org/PathwayBrowser/#/R-DME-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Drosophila melanogaster 58359 R-DME-9748957 https://reactome.org/PathwayBrowser/#/R-DME-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Drosophila melanogaster 58359 R-DRE-197271 https://reactome.org/PathwayBrowser/#/R-DRE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Danio rerio 58359 R-DRE-212642 https://reactome.org/PathwayBrowser/#/R-DRE-212642 L-Glutamine transport into neurons IEA Danio rerio 58359 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 58359 R-DRE-352108 https://reactome.org/PathwayBrowser/#/R-DRE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Danio rerio 58359 R-DRE-352182 https://reactome.org/PathwayBrowser/#/R-DRE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Danio rerio 58359 R-DRE-352379 https://reactome.org/PathwayBrowser/#/R-DRE-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Danio rerio 58359 R-DRE-352385 https://reactome.org/PathwayBrowser/#/R-DRE-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Danio rerio 58359 R-DRE-375473 https://reactome.org/PathwayBrowser/#/R-DRE-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Danio rerio 58359 R-DRE-449715 https://reactome.org/PathwayBrowser/#/R-DRE-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Danio rerio 58359 R-DRE-504054 https://reactome.org/PathwayBrowser/#/R-DRE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Danio rerio 58359 R-DRE-70606 https://reactome.org/PathwayBrowser/#/R-DRE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Danio rerio 58359 R-DRE-70609 https://reactome.org/PathwayBrowser/#/R-DRE-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Danio rerio 58359 R-DRE-73647 https://reactome.org/PathwayBrowser/#/R-DRE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Danio rerio 58359 R-DRE-73815 https://reactome.org/PathwayBrowser/#/R-DRE-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Danio rerio 58359 R-DRE-893616 https://reactome.org/PathwayBrowser/#/R-DRE-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Danio rerio 58359 R-GGA-197271 https://reactome.org/PathwayBrowser/#/R-GGA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Gallus gallus 58359 R-GGA-212614 https://reactome.org/PathwayBrowser/#/R-GGA-212614 Glutamine transport from astrocytes IEA Gallus gallus 58359 R-GGA-212642 https://reactome.org/PathwayBrowser/#/R-GGA-212642 L-Glutamine transport into neurons IEA Gallus gallus 58359 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 58359 R-GGA-352108 https://reactome.org/PathwayBrowser/#/R-GGA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Gallus gallus 58359 R-GGA-352119 https://reactome.org/PathwayBrowser/#/R-GGA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Gallus gallus 58359 R-GGA-352174 https://reactome.org/PathwayBrowser/#/R-GGA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Gallus gallus 58359 R-GGA-375473 https://reactome.org/PathwayBrowser/#/R-GGA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Gallus gallus 58359 R-GGA-419144 https://reactome.org/PathwayBrowser/#/R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate TAS Gallus gallus 58359 R-GGA-419152 https://reactome.org/PathwayBrowser/#/R-GGA-419152 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate TAS Gallus gallus 58359 R-GGA-419440 https://reactome.org/PathwayBrowser/#/R-GGA-419440 L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate IEA Gallus gallus 58359 R-GGA-421218 https://reactome.org/PathwayBrowser/#/R-GGA-421218 xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate IEA Gallus gallus 58359 R-GGA-449715 https://reactome.org/PathwayBrowser/#/R-GGA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Gallus gallus 58359 R-GGA-504054 https://reactome.org/PathwayBrowser/#/R-GGA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Gallus gallus 58359 R-GGA-70599 https://reactome.org/PathwayBrowser/#/R-GGA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Gallus gallus 58359 R-GGA-70606 https://reactome.org/PathwayBrowser/#/R-GGA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Gallus gallus 58359 R-GGA-70609 https://reactome.org/PathwayBrowser/#/R-GGA-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Gallus gallus 58359 R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus 58359 R-GGA-73792 https://reactome.org/PathwayBrowser/#/R-GGA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Gallus gallus 58359 R-GGA-73815 https://reactome.org/PathwayBrowser/#/R-GGA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Gallus gallus 58359 R-GGA-893616 https://reactome.org/PathwayBrowser/#/R-GGA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Gallus gallus 58359 R-GGA-9748957 https://reactome.org/PathwayBrowser/#/R-GGA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Gallus gallus 58359 R-HSA-177160 https://reactome.org/PathwayBrowser/#/R-HSA-177160 phenylacetyl-CoA + glutamine => phenylacetyl glutamine + Coenzyme A TAS Homo sapiens 58359 R-HSA-197271 https://reactome.org/PathwayBrowser/#/R-HSA-197271 NADSYN1 hexamer amidates NAAD to NAD+ TAS Homo sapiens 58359 R-HSA-212614 https://reactome.org/PathwayBrowser/#/R-HSA-212614 Glutamine transport from astrocytes TAS Homo sapiens 58359 R-HSA-212642 https://reactome.org/PathwayBrowser/#/R-HSA-212642 L-Glutamine transport into neurons TAS Homo sapiens 58359 R-HSA-212651 https://reactome.org/PathwayBrowser/#/R-HSA-212651 Transport of L-Glutamine (cytosol) to mitochondrial matrix TAS Homo sapiens 58359 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 58359 R-HSA-352108 https://reactome.org/PathwayBrowser/#/R-HSA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids TAS Homo sapiens 58359 R-HSA-352119 https://reactome.org/PathwayBrowser/#/R-HSA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids TAS Homo sapiens 58359 R-HSA-352174 https://reactome.org/PathwayBrowser/#/R-HSA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine TAS Homo sapiens 58359 R-HSA-352182 https://reactome.org/PathwayBrowser/#/R-HSA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine TAS Homo sapiens 58359 R-HSA-352191 https://reactome.org/PathwayBrowser/#/R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids TAS Homo sapiens 58359 R-HSA-352379 https://reactome.org/PathwayBrowser/#/R-HSA-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane TAS Homo sapiens 58359 R-HSA-352385 https://reactome.org/PathwayBrowser/#/R-HSA-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane TAS Homo sapiens 58359 R-HSA-375473 https://reactome.org/PathwayBrowser/#/R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 58359 R-HSA-379982 https://reactome.org/PathwayBrowser/#/R-HSA-379982 glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate TAS Homo sapiens 58359 R-HSA-380241 https://reactome.org/PathwayBrowser/#/R-HSA-380241 glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate TAS Homo sapiens 58359 R-HSA-4085027 https://reactome.org/PathwayBrowser/#/R-HSA-4085027 Defective GFPT1 does not transfer an amino group from L-Gln to F6P to form GlcN6P TAS Homo sapiens 58359 R-HSA-449715 https://reactome.org/PathwayBrowser/#/R-HSA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P TAS Homo sapiens 58359 R-HSA-504054 https://reactome.org/PathwayBrowser/#/R-HSA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] TAS Homo sapiens 58359 R-HSA-5659734 https://reactome.org/PathwayBrowser/#/R-HSA-5659734 Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol TAS Homo sapiens 58359 R-HSA-70599 https://reactome.org/PathwayBrowser/#/R-HSA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] TAS Homo sapiens 58359 R-HSA-70606 https://reactome.org/PathwayBrowser/#/R-HSA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] TAS Homo sapiens 58359 R-HSA-70609 https://reactome.org/PathwayBrowser/#/R-HSA-70609 glutamine + H2O => glutamate + NH4+ [GLS] TAS Homo sapiens 58359 R-HSA-73577 https://reactome.org/PathwayBrowser/#/R-HSA-73577 CAD hexamer transforms L-Gln to CAP TAS Homo sapiens 58359 R-HSA-73647 https://reactome.org/PathwayBrowser/#/R-HSA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] TAS Homo sapiens 58359 R-HSA-73792 https://reactome.org/PathwayBrowser/#/R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate TAS Homo sapiens 58359 R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 58359 R-HSA-73815 https://reactome.org/PathwayBrowser/#/R-HSA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate TAS Homo sapiens 58359 R-HSA-893616 https://reactome.org/PathwayBrowser/#/R-HSA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine TAS Homo sapiens 58359 R-HSA-9748957 https://reactome.org/PathwayBrowser/#/R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP TAS Homo sapiens 58359 R-MMU-197271 https://reactome.org/PathwayBrowser/#/R-MMU-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Mus musculus 58359 R-MMU-212614 https://reactome.org/PathwayBrowser/#/R-MMU-212614 Glutamine transport from astrocytes IEA Mus musculus 58359 R-MMU-212642 https://reactome.org/PathwayBrowser/#/R-MMU-212642 L-Glutamine transport into neurons IEA Mus musculus 58359 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 58359 R-MMU-352108 https://reactome.org/PathwayBrowser/#/R-MMU-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Mus musculus 58359 R-MMU-352119 https://reactome.org/PathwayBrowser/#/R-MMU-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Mus musculus 58359 R-MMU-352174 https://reactome.org/PathwayBrowser/#/R-MMU-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Mus musculus 58359 R-MMU-352182 https://reactome.org/PathwayBrowser/#/R-MMU-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Mus musculus 58359 R-MMU-352191 https://reactome.org/PathwayBrowser/#/R-MMU-352191 SLC7A8-mediated uptake of neutral amino acids IEA Mus musculus 58359 R-MMU-352379 https://reactome.org/PathwayBrowser/#/R-MMU-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Mus musculus 58359 R-MMU-352385 https://reactome.org/PathwayBrowser/#/R-MMU-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Mus musculus 58359 R-MMU-375473 https://reactome.org/PathwayBrowser/#/R-MMU-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Mus musculus 58359 R-MMU-449715 https://reactome.org/PathwayBrowser/#/R-MMU-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Mus musculus 58359 R-MMU-504054 https://reactome.org/PathwayBrowser/#/R-MMU-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Mus musculus 58359 R-MMU-70599 https://reactome.org/PathwayBrowser/#/R-MMU-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Mus musculus 58359 R-MMU-70606 https://reactome.org/PathwayBrowser/#/R-MMU-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Mus musculus 58359 R-MMU-70609 https://reactome.org/PathwayBrowser/#/R-MMU-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Mus musculus 58359 R-MMU-73577 https://reactome.org/PathwayBrowser/#/R-MMU-73577 CAD hexamer transforms L-Gln to CAP IEA Mus musculus 58359 R-MMU-73647 https://reactome.org/PathwayBrowser/#/R-MMU-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Mus musculus 58359 R-MMU-73792 https://reactome.org/PathwayBrowser/#/R-MMU-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Mus musculus 58359 R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 58359 R-MMU-73815 https://reactome.org/PathwayBrowser/#/R-MMU-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Mus musculus 58359 R-MMU-893616 https://reactome.org/PathwayBrowser/#/R-MMU-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Mus musculus 58359 R-MMU-9748957 https://reactome.org/PathwayBrowser/#/R-MMU-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Mus musculus 58359 R-PFA-197271 https://reactome.org/PathwayBrowser/#/R-PFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Plasmodium falciparum 58359 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 58359 R-PFA-375473 https://reactome.org/PathwayBrowser/#/R-PFA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 58359 R-PFA-449715 https://reactome.org/PathwayBrowser/#/R-PFA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Plasmodium falciparum 58359 R-PFA-504054 https://reactome.org/PathwayBrowser/#/R-PFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Plasmodium falciparum 58359 R-PFA-70599 https://reactome.org/PathwayBrowser/#/R-PFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Plasmodium falciparum 58359 R-PFA-73577 https://reactome.org/PathwayBrowser/#/R-PFA-73577 CAD hexamer transforms L-Gln to CAP IEA Plasmodium falciparum 58359 R-PFA-73647 https://reactome.org/PathwayBrowser/#/R-PFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Plasmodium falciparum 58359 R-PFA-73792 https://reactome.org/PathwayBrowser/#/R-PFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Plasmodium falciparum 58359 R-PFA-9748957 https://reactome.org/PathwayBrowser/#/R-PFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Plasmodium falciparum 58359 R-RNO-197271 https://reactome.org/PathwayBrowser/#/R-RNO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Rattus norvegicus 58359 R-RNO-212614 https://reactome.org/PathwayBrowser/#/R-RNO-212614 Glutamine transport from astrocytes IEA Rattus norvegicus 58359 R-RNO-212642 https://reactome.org/PathwayBrowser/#/R-RNO-212642 L-Glutamine transport into neurons IEA Rattus norvegicus 58359 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 58359 R-RNO-352108 https://reactome.org/PathwayBrowser/#/R-RNO-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Rattus norvegicus 58359 R-RNO-352119 https://reactome.org/PathwayBrowser/#/R-RNO-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Rattus norvegicus 58359 R-RNO-352174 https://reactome.org/PathwayBrowser/#/R-RNO-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Rattus norvegicus 58359 R-RNO-352182 https://reactome.org/PathwayBrowser/#/R-RNO-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Rattus norvegicus 58359 R-RNO-352191 https://reactome.org/PathwayBrowser/#/R-RNO-352191 SLC7A8-mediated uptake of neutral amino acids IEA Rattus norvegicus 58359 R-RNO-352379 https://reactome.org/PathwayBrowser/#/R-RNO-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Rattus norvegicus 58359 R-RNO-352385 https://reactome.org/PathwayBrowser/#/R-RNO-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Rattus norvegicus 58359 R-RNO-375473 https://reactome.org/PathwayBrowser/#/R-RNO-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Rattus norvegicus 58359 R-RNO-449715 https://reactome.org/PathwayBrowser/#/R-RNO-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Rattus norvegicus 58359 R-RNO-504054 https://reactome.org/PathwayBrowser/#/R-RNO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Rattus norvegicus 58359 R-RNO-70599 https://reactome.org/PathwayBrowser/#/R-RNO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Rattus norvegicus 58359 R-RNO-70606 https://reactome.org/PathwayBrowser/#/R-RNO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Rattus norvegicus 58359 R-RNO-70609 https://reactome.org/PathwayBrowser/#/R-RNO-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Rattus norvegicus 58359 R-RNO-73577 https://reactome.org/PathwayBrowser/#/R-RNO-73577 CAD hexamer transforms L-Gln to CAP IEA Rattus norvegicus 58359 R-RNO-73647 https://reactome.org/PathwayBrowser/#/R-RNO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Rattus norvegicus 58359 R-RNO-73792 https://reactome.org/PathwayBrowser/#/R-RNO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Rattus norvegicus 58359 R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 58359 R-RNO-73815 https://reactome.org/PathwayBrowser/#/R-RNO-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Rattus norvegicus 58359 R-RNO-893616 https://reactome.org/PathwayBrowser/#/R-RNO-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Rattus norvegicus 58359 R-RNO-9748957 https://reactome.org/PathwayBrowser/#/R-RNO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Rattus norvegicus 58359 R-SCE-197271 https://reactome.org/PathwayBrowser/#/R-SCE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Saccharomyces cerevisiae 58359 R-SCE-212614 https://reactome.org/PathwayBrowser/#/R-SCE-212614 Glutamine transport from astrocytes IEA Saccharomyces cerevisiae 58359 R-SCE-212642 https://reactome.org/PathwayBrowser/#/R-SCE-212642 L-Glutamine transport into neurons IEA Saccharomyces cerevisiae 58359 R-SCE-352108 https://reactome.org/PathwayBrowser/#/R-SCE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 58359 R-SCE-352119 https://reactome.org/PathwayBrowser/#/R-SCE-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 58359 R-SCE-352174 https://reactome.org/PathwayBrowser/#/R-SCE-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Saccharomyces cerevisiae 58359 R-SCE-352182 https://reactome.org/PathwayBrowser/#/R-SCE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Saccharomyces cerevisiae 58359 R-SCE-449715 https://reactome.org/PathwayBrowser/#/R-SCE-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Saccharomyces cerevisiae 58359 R-SCE-504054 https://reactome.org/PathwayBrowser/#/R-SCE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Saccharomyces cerevisiae 58359 R-SCE-70599 https://reactome.org/PathwayBrowser/#/R-SCE-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Saccharomyces cerevisiae 58359 R-SCE-70606 https://reactome.org/PathwayBrowser/#/R-SCE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Saccharomyces cerevisiae 58359 R-SCE-73577 https://reactome.org/PathwayBrowser/#/R-SCE-73577 CAD hexamer transforms L-Gln to CAP IEA Saccharomyces cerevisiae 58359 R-SCE-73647 https://reactome.org/PathwayBrowser/#/R-SCE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Saccharomyces cerevisiae 58359 R-SCE-73792 https://reactome.org/PathwayBrowser/#/R-SCE-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Saccharomyces cerevisiae 58359 R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 58359 R-SCE-893616 https://reactome.org/PathwayBrowser/#/R-SCE-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Saccharomyces cerevisiae 58359 R-SCE-9748957 https://reactome.org/PathwayBrowser/#/R-SCE-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Saccharomyces cerevisiae 58359 R-SPO-197271 https://reactome.org/PathwayBrowser/#/R-SPO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Schizosaccharomyces pombe 58359 R-SPO-449715 https://reactome.org/PathwayBrowser/#/R-SPO-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Schizosaccharomyces pombe 58359 R-SPO-504054 https://reactome.org/PathwayBrowser/#/R-SPO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Schizosaccharomyces pombe 58359 R-SPO-70599 https://reactome.org/PathwayBrowser/#/R-SPO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Schizosaccharomyces pombe 58359 R-SPO-70606 https://reactome.org/PathwayBrowser/#/R-SPO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Schizosaccharomyces pombe 58359 R-SPO-73577 https://reactome.org/PathwayBrowser/#/R-SPO-73577 CAD hexamer transforms L-Gln to CAP IEA Schizosaccharomyces pombe 58359 R-SPO-73647 https://reactome.org/PathwayBrowser/#/R-SPO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Schizosaccharomyces pombe 58359 R-SPO-73792 https://reactome.org/PathwayBrowser/#/R-SPO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Schizosaccharomyces pombe 58359 R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 58359 R-SPO-893616 https://reactome.org/PathwayBrowser/#/R-SPO-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Schizosaccharomyces pombe 58359 R-SPO-9748957 https://reactome.org/PathwayBrowser/#/R-SPO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Schizosaccharomyces pombe 58359 R-SSC-197271 https://reactome.org/PathwayBrowser/#/R-SSC-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Sus scrofa 58359 R-SSC-212614 https://reactome.org/PathwayBrowser/#/R-SSC-212614 Glutamine transport from astrocytes IEA Sus scrofa 58359 R-SSC-212642 https://reactome.org/PathwayBrowser/#/R-SSC-212642 L-Glutamine transport into neurons IEA Sus scrofa 58359 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 58359 R-SSC-352108 https://reactome.org/PathwayBrowser/#/R-SSC-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Sus scrofa 58359 R-SSC-352119 https://reactome.org/PathwayBrowser/#/R-SSC-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Sus scrofa 58359 R-SSC-352174 https://reactome.org/PathwayBrowser/#/R-SSC-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Sus scrofa 58359 R-SSC-352182 https://reactome.org/PathwayBrowser/#/R-SSC-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Sus scrofa 58359 R-SSC-352191 https://reactome.org/PathwayBrowser/#/R-SSC-352191 SLC7A8-mediated uptake of neutral amino acids IEA Sus scrofa 58359 R-SSC-352379 https://reactome.org/PathwayBrowser/#/R-SSC-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Sus scrofa 58359 R-SSC-352385 https://reactome.org/PathwayBrowser/#/R-SSC-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Sus scrofa 58359 R-SSC-375473 https://reactome.org/PathwayBrowser/#/R-SSC-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Sus scrofa 58359 R-SSC-449715 https://reactome.org/PathwayBrowser/#/R-SSC-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Sus scrofa 58359 R-SSC-504054 https://reactome.org/PathwayBrowser/#/R-SSC-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Sus scrofa 58359 R-SSC-70599 https://reactome.org/PathwayBrowser/#/R-SSC-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Sus scrofa 58359 R-SSC-70606 https://reactome.org/PathwayBrowser/#/R-SSC-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Sus scrofa 58359 R-SSC-70609 https://reactome.org/PathwayBrowser/#/R-SSC-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Sus scrofa 58359 R-SSC-73577 https://reactome.org/PathwayBrowser/#/R-SSC-73577 CAD hexamer transforms L-Gln to CAP IEA Sus scrofa 58359 R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa 58359 R-SSC-73792 https://reactome.org/PathwayBrowser/#/R-SSC-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Sus scrofa 58359 R-SSC-73815 https://reactome.org/PathwayBrowser/#/R-SSC-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Sus scrofa 58359 R-SSC-893616 https://reactome.org/PathwayBrowser/#/R-SSC-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Sus scrofa 58359 R-SSC-9748957 https://reactome.org/PathwayBrowser/#/R-SSC-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Sus scrofa 58359 R-XTR-212614 https://reactome.org/PathwayBrowser/#/R-XTR-212614 Glutamine transport from astrocytes IEA Xenopus tropicalis 58359 R-XTR-212642 https://reactome.org/PathwayBrowser/#/R-XTR-212642 L-Glutamine transport into neurons IEA Xenopus tropicalis 58359 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 58359 R-XTR-352108 https://reactome.org/PathwayBrowser/#/R-XTR-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 58359 R-XTR-352119 https://reactome.org/PathwayBrowser/#/R-XTR-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 58359 R-XTR-352174 https://reactome.org/PathwayBrowser/#/R-XTR-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Xenopus tropicalis 58359 R-XTR-352182 https://reactome.org/PathwayBrowser/#/R-XTR-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Xenopus tropicalis 58359 R-XTR-352191 https://reactome.org/PathwayBrowser/#/R-XTR-352191 SLC7A8-mediated uptake of neutral amino acids IEA Xenopus tropicalis 58359 R-XTR-352379 https://reactome.org/PathwayBrowser/#/R-XTR-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane IEA Xenopus tropicalis 58359 R-XTR-352385 https://reactome.org/PathwayBrowser/#/R-XTR-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane IEA Xenopus tropicalis 58359 R-XTR-375473 https://reactome.org/PathwayBrowser/#/R-XTR-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 58359 R-XTR-449715 https://reactome.org/PathwayBrowser/#/R-XTR-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Xenopus tropicalis 58359 R-XTR-70599 https://reactome.org/PathwayBrowser/#/R-XTR-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Xenopus tropicalis 58359 R-XTR-70606 https://reactome.org/PathwayBrowser/#/R-XTR-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Xenopus tropicalis 58359 R-XTR-70609 https://reactome.org/PathwayBrowser/#/R-XTR-70609 glutamine + H2O => glutamate + NH4+ [GLS] IEA Xenopus tropicalis 58359 R-XTR-73577 https://reactome.org/PathwayBrowser/#/R-XTR-73577 CAD hexamer transforms L-Gln to CAP IEA Xenopus tropicalis 58359 R-XTR-73792 https://reactome.org/PathwayBrowser/#/R-XTR-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Xenopus tropicalis 58359 R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 58359 R-XTR-73815 https://reactome.org/PathwayBrowser/#/R-XTR-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Xenopus tropicalis 58359 R-XTR-893616 https://reactome.org/PathwayBrowser/#/R-XTR-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Xenopus tropicalis 58359 R-XTR-9748957 https://reactome.org/PathwayBrowser/#/R-XTR-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Xenopus tropicalis 58367 R-BTA-1638104 https://reactome.org/PathwayBrowser/#/R-BTA-1638104 UGCG transfers glucose to ceramide IEA Bos taurus 58367 R-BTA-173597 https://reactome.org/PathwayBrowser/#/R-BTA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Bos taurus 58367 R-BTA-1981157 https://reactome.org/PathwayBrowser/#/R-BTA-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Bos taurus 58367 R-BTA-3322001 https://reactome.org/PathwayBrowser/#/R-BTA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Bos taurus 58367 R-BTA-3322003 https://reactome.org/PathwayBrowser/#/R-BTA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Bos taurus 58367 R-BTA-3322009 https://reactome.org/PathwayBrowser/#/R-BTA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Bos taurus 58367 R-BTA-3322014 https://reactome.org/PathwayBrowser/#/R-BTA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Bos taurus 58367 R-BTA-3322019 https://reactome.org/PathwayBrowser/#/R-BTA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Bos taurus 58367 R-BTA-3322025 https://reactome.org/PathwayBrowser/#/R-BTA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Bos taurus 58367 R-BTA-3322041 https://reactome.org/PathwayBrowser/#/R-BTA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Bos taurus 58367 R-BTA-3780994 https://reactome.org/PathwayBrowser/#/R-BTA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Bos taurus 58367 R-BTA-3781024 https://reactome.org/PathwayBrowser/#/R-BTA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Bos taurus 58367 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 58367 R-BTA-417858 https://reactome.org/PathwayBrowser/#/R-BTA-417858 P2Y14 receptor can bind to UDP-glucose IEA Bos taurus 58367 R-BTA-446214 https://reactome.org/PathwayBrowser/#/R-BTA-446214 Synthesis of dolichyl-phosphate-glucose IEA Bos taurus 58367 R-BTA-5173005 https://reactome.org/PathwayBrowser/#/R-BTA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Bos taurus 58367 R-BTA-6810464 https://reactome.org/PathwayBrowser/#/R-BTA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Bos taurus 58367 R-BTA-70286 https://reactome.org/PathwayBrowser/#/R-BTA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Bos taurus 58367 R-BTA-70361 https://reactome.org/PathwayBrowser/#/R-BTA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Bos taurus 58367 R-BTA-70369 https://reactome.org/PathwayBrowser/#/R-BTA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Bos taurus 58367 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 58367 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 58367 R-BTA-9792608 https://reactome.org/PathwayBrowser/#/R-BTA-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Bos taurus 58367 R-CEL-1638104 https://reactome.org/PathwayBrowser/#/R-CEL-1638104 UGCG transfers glucose to ceramide IEA Caenorhabditis elegans 58367 R-CEL-173597 https://reactome.org/PathwayBrowser/#/R-CEL-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Caenorhabditis elegans 58367 R-CEL-1981157 https://reactome.org/PathwayBrowser/#/R-CEL-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Caenorhabditis elegans 58367 R-CEL-3322001 https://reactome.org/PathwayBrowser/#/R-CEL-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Caenorhabditis elegans 58367 R-CEL-3322003 https://reactome.org/PathwayBrowser/#/R-CEL-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Caenorhabditis elegans 58367 R-CEL-3322009 https://reactome.org/PathwayBrowser/#/R-CEL-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Caenorhabditis elegans 58367 R-CEL-3322014 https://reactome.org/PathwayBrowser/#/R-CEL-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Caenorhabditis elegans 58367 R-CEL-3322019 https://reactome.org/PathwayBrowser/#/R-CEL-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Caenorhabditis elegans 58367 R-CEL-3322025 https://reactome.org/PathwayBrowser/#/R-CEL-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Caenorhabditis elegans 58367 R-CEL-3322041 https://reactome.org/PathwayBrowser/#/R-CEL-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Caenorhabditis elegans 58367 R-CEL-3780994 https://reactome.org/PathwayBrowser/#/R-CEL-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Caenorhabditis elegans 58367 R-CEL-3781024 https://reactome.org/PathwayBrowser/#/R-CEL-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Caenorhabditis elegans 58367 R-CEL-446214 https://reactome.org/PathwayBrowser/#/R-CEL-446214 Synthesis of dolichyl-phosphate-glucose IEA Caenorhabditis elegans 58367 R-CEL-5173005 https://reactome.org/PathwayBrowser/#/R-CEL-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Caenorhabditis elegans 58367 R-CEL-6810464 https://reactome.org/PathwayBrowser/#/R-CEL-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Caenorhabditis elegans 58367 R-CEL-70286 https://reactome.org/PathwayBrowser/#/R-CEL-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Caenorhabditis elegans 58367 R-CEL-70361 https://reactome.org/PathwayBrowser/#/R-CEL-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Caenorhabditis elegans 58367 R-CEL-70369 https://reactome.org/PathwayBrowser/#/R-CEL-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Caenorhabditis elegans 58367 R-CEL-9792608 https://reactome.org/PathwayBrowser/#/R-CEL-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Caenorhabditis elegans 58367 R-CFA-1638104 https://reactome.org/PathwayBrowser/#/R-CFA-1638104 UGCG transfers glucose to ceramide IEA Canis familiaris 58367 R-CFA-173597 https://reactome.org/PathwayBrowser/#/R-CFA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Canis familiaris 58367 R-CFA-1981157 https://reactome.org/PathwayBrowser/#/R-CFA-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Canis familiaris 58367 R-CFA-3322001 https://reactome.org/PathwayBrowser/#/R-CFA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Canis familiaris 58367 R-CFA-3322003 https://reactome.org/PathwayBrowser/#/R-CFA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Canis familiaris 58367 R-CFA-3322009 https://reactome.org/PathwayBrowser/#/R-CFA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Canis familiaris 58367 R-CFA-3322014 https://reactome.org/PathwayBrowser/#/R-CFA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Canis familiaris 58367 R-CFA-3322019 https://reactome.org/PathwayBrowser/#/R-CFA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Canis familiaris 58367 R-CFA-3322025 https://reactome.org/PathwayBrowser/#/R-CFA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Canis familiaris 58367 R-CFA-3322041 https://reactome.org/PathwayBrowser/#/R-CFA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Canis familiaris 58367 R-CFA-3780994 https://reactome.org/PathwayBrowser/#/R-CFA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Canis familiaris 58367 R-CFA-3781024 https://reactome.org/PathwayBrowser/#/R-CFA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Canis familiaris 58367 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 58367 R-CFA-417858 https://reactome.org/PathwayBrowser/#/R-CFA-417858 P2Y14 receptor can bind to UDP-glucose IEA Canis familiaris 58367 R-CFA-446214 https://reactome.org/PathwayBrowser/#/R-CFA-446214 Synthesis of dolichyl-phosphate-glucose IEA Canis familiaris 58367 R-CFA-5173005 https://reactome.org/PathwayBrowser/#/R-CFA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Canis familiaris 58367 R-CFA-70286 https://reactome.org/PathwayBrowser/#/R-CFA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Canis familiaris 58367 R-CFA-70361 https://reactome.org/PathwayBrowser/#/R-CFA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Canis familiaris 58367 R-CFA-70369 https://reactome.org/PathwayBrowser/#/R-CFA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Canis familiaris 58367 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 58367 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 58367 R-CFA-9792608 https://reactome.org/PathwayBrowser/#/R-CFA-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Canis familiaris 58367 R-DDI-3322001 https://reactome.org/PathwayBrowser/#/R-DDI-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Dictyostelium discoideum 58367 R-DDI-3322003 https://reactome.org/PathwayBrowser/#/R-DDI-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Dictyostelium discoideum 58367 R-DDI-3322009 https://reactome.org/PathwayBrowser/#/R-DDI-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Dictyostelium discoideum 58367 R-DDI-3322014 https://reactome.org/PathwayBrowser/#/R-DDI-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Dictyostelium discoideum 58367 R-DDI-3322019 https://reactome.org/PathwayBrowser/#/R-DDI-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Dictyostelium discoideum 58367 R-DDI-3322025 https://reactome.org/PathwayBrowser/#/R-DDI-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Dictyostelium discoideum 58367 R-DDI-3322041 https://reactome.org/PathwayBrowser/#/R-DDI-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Dictyostelium discoideum 58367 R-DDI-446214 https://reactome.org/PathwayBrowser/#/R-DDI-446214 Synthesis of dolichyl-phosphate-glucose IEA Dictyostelium discoideum 58367 R-DDI-70286 https://reactome.org/PathwayBrowser/#/R-DDI-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Dictyostelium discoideum 58367 R-DDI-70369 https://reactome.org/PathwayBrowser/#/R-DDI-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Dictyostelium discoideum 58367 R-DDI-9792608 https://reactome.org/PathwayBrowser/#/R-DDI-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Dictyostelium discoideum 58367 R-DME-1638104 https://reactome.org/PathwayBrowser/#/R-DME-1638104 UGCG transfers glucose to ceramide IEA Drosophila melanogaster 58367 R-DME-173597 https://reactome.org/PathwayBrowser/#/R-DME-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Drosophila melanogaster 58367 R-DME-1981157 https://reactome.org/PathwayBrowser/#/R-DME-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Drosophila melanogaster 58367 R-DME-3322001 https://reactome.org/PathwayBrowser/#/R-DME-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Drosophila melanogaster 58367 R-DME-3322003 https://reactome.org/PathwayBrowser/#/R-DME-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Drosophila melanogaster 58367 R-DME-3322009 https://reactome.org/PathwayBrowser/#/R-DME-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Drosophila melanogaster 58367 R-DME-3322014 https://reactome.org/PathwayBrowser/#/R-DME-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Drosophila melanogaster 58367 R-DME-3322019 https://reactome.org/PathwayBrowser/#/R-DME-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Drosophila melanogaster 58367 R-DME-3322025 https://reactome.org/PathwayBrowser/#/R-DME-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Drosophila melanogaster 58367 R-DME-3322041 https://reactome.org/PathwayBrowser/#/R-DME-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Drosophila melanogaster 58367 R-DME-3780994 https://reactome.org/PathwayBrowser/#/R-DME-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Drosophila melanogaster 58367 R-DME-3781024 https://reactome.org/PathwayBrowser/#/R-DME-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Drosophila melanogaster 58367 R-DME-446214 https://reactome.org/PathwayBrowser/#/R-DME-446214 Synthesis of dolichyl-phosphate-glucose IEA Drosophila melanogaster 58367 R-DME-5173005 https://reactome.org/PathwayBrowser/#/R-DME-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Drosophila melanogaster 58367 R-DME-6810464 https://reactome.org/PathwayBrowser/#/R-DME-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Drosophila melanogaster 58367 R-DME-70286 https://reactome.org/PathwayBrowser/#/R-DME-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Drosophila melanogaster 58367 R-DME-70361 https://reactome.org/PathwayBrowser/#/R-DME-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Drosophila melanogaster 58367 R-DME-70369 https://reactome.org/PathwayBrowser/#/R-DME-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Drosophila melanogaster 58367 R-DME-9792608 https://reactome.org/PathwayBrowser/#/R-DME-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Drosophila melanogaster 58367 R-DRE-1638104 https://reactome.org/PathwayBrowser/#/R-DRE-1638104 UGCG transfers glucose to ceramide IEA Danio rerio 58367 R-DRE-173597 https://reactome.org/PathwayBrowser/#/R-DRE-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Danio rerio 58367 R-DRE-1981157 https://reactome.org/PathwayBrowser/#/R-DRE-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Danio rerio 58367 R-DRE-3322001 https://reactome.org/PathwayBrowser/#/R-DRE-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Danio rerio 58367 R-DRE-3322003 https://reactome.org/PathwayBrowser/#/R-DRE-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Danio rerio 58367 R-DRE-3322025 https://reactome.org/PathwayBrowser/#/R-DRE-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Danio rerio 58367 R-DRE-3322041 https://reactome.org/PathwayBrowser/#/R-DRE-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Danio rerio 58367 R-DRE-3781024 https://reactome.org/PathwayBrowser/#/R-DRE-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Danio rerio 58367 R-DRE-446214 https://reactome.org/PathwayBrowser/#/R-DRE-446214 Synthesis of dolichyl-phosphate-glucose IEA Danio rerio 58367 R-DRE-5173005 https://reactome.org/PathwayBrowser/#/R-DRE-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Danio rerio 58367 R-DRE-6810464 https://reactome.org/PathwayBrowser/#/R-DRE-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Danio rerio 58367 R-DRE-70369 https://reactome.org/PathwayBrowser/#/R-DRE-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Danio rerio 58367 R-GGA-1638104 https://reactome.org/PathwayBrowser/#/R-GGA-1638104 UGCG transfers glucose to ceramide IEA Gallus gallus 58367 R-GGA-173597 https://reactome.org/PathwayBrowser/#/R-GGA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Gallus gallus 58367 R-GGA-3322001 https://reactome.org/PathwayBrowser/#/R-GGA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Gallus gallus 58367 R-GGA-3322003 https://reactome.org/PathwayBrowser/#/R-GGA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Gallus gallus 58367 R-GGA-3322009 https://reactome.org/PathwayBrowser/#/R-GGA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Gallus gallus 58367 R-GGA-3322014 https://reactome.org/PathwayBrowser/#/R-GGA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Gallus gallus 58367 R-GGA-3322019 https://reactome.org/PathwayBrowser/#/R-GGA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Gallus gallus 58367 R-GGA-3322025 https://reactome.org/PathwayBrowser/#/R-GGA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Gallus gallus 58367 R-GGA-3322041 https://reactome.org/PathwayBrowser/#/R-GGA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Gallus gallus 58367 R-GGA-3780994 https://reactome.org/PathwayBrowser/#/R-GGA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Gallus gallus 58367 R-GGA-3781024 https://reactome.org/PathwayBrowser/#/R-GGA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Gallus gallus 58367 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 58367 R-GGA-417858 https://reactome.org/PathwayBrowser/#/R-GGA-417858 P2Y14 receptor can bind to UDP-glucose IEA Gallus gallus 58367 R-GGA-446214 https://reactome.org/PathwayBrowser/#/R-GGA-446214 Synthesis of dolichyl-phosphate-glucose IEA Gallus gallus 58367 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus 58367 R-GGA-6810464 https://reactome.org/PathwayBrowser/#/R-GGA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Gallus gallus 58367 R-GGA-70286 https://reactome.org/PathwayBrowser/#/R-GGA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Gallus gallus 58367 R-GGA-70369 https://reactome.org/PathwayBrowser/#/R-GGA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Gallus gallus 58367 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 58367 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 58367 R-GGA-9792608 https://reactome.org/PathwayBrowser/#/R-GGA-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Gallus gallus 58367 R-HSA-1638104 https://reactome.org/PathwayBrowser/#/R-HSA-1638104 UGCG transfers glucose to ceramide TAS Homo sapiens 58367 R-HSA-173597 https://reactome.org/PathwayBrowser/#/R-HSA-173597 UDP-glucose is oxidised to UDP-glucuronate TAS Homo sapiens 58367 R-HSA-1912353 https://reactome.org/PathwayBrowser/#/R-HSA-1912353 Glucosylation of Pre-NOTCH by POGLUT1 IEA Homo sapiens 58367 R-HSA-1981157 https://reactome.org/PathwayBrowser/#/R-HSA-1981157 Glucosylation of collagen propeptide hydroxylysines TAS Homo sapiens 58367 R-HSA-3322001 https://reactome.org/PathwayBrowser/#/R-HSA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 TAS Homo sapiens 58367 R-HSA-3322003 https://reactome.org/PathwayBrowser/#/R-HSA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b TAS Homo sapiens 58367 R-HSA-3322009 https://reactome.org/PathwayBrowser/#/R-HSA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 TAS Homo sapiens 58367 R-HSA-3322014 https://reactome.org/PathwayBrowser/#/R-HSA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a TAS Homo sapiens 58367 R-HSA-3322019 https://reactome.org/PathwayBrowser/#/R-HSA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b TAS Homo sapiens 58367 R-HSA-3322025 https://reactome.org/PathwayBrowser/#/R-HSA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a TAS Homo sapiens 58367 R-HSA-3322041 https://reactome.org/PathwayBrowser/#/R-HSA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 TAS Homo sapiens 58367 R-HSA-3780994 https://reactome.org/PathwayBrowser/#/R-HSA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 TAS Homo sapiens 58367 R-HSA-3781024 https://reactome.org/PathwayBrowser/#/R-HSA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 TAS Homo sapiens 58367 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 58367 R-HSA-3814838 https://reactome.org/PathwayBrowser/#/R-HSA-3814838 Defective GYG1 is not autoglucosyolated TAS Homo sapiens 58367 R-HSA-3828061 https://reactome.org/PathwayBrowser/#/R-HSA-3828061 Defective GYS1 does not transfer glucose to growing glycogen chains TAS Homo sapiens 58367 R-HSA-3858506 https://reactome.org/PathwayBrowser/#/R-HSA-3858506 Defective GYS2 does not transfer glucose to growing glycogen chains TAS Homo sapiens 58367 R-HSA-417858 https://reactome.org/PathwayBrowser/#/R-HSA-417858 P2Y14 receptor can bind to UDP-glucose TAS Homo sapiens 58367 R-HSA-446214 https://reactome.org/PathwayBrowser/#/R-HSA-446214 Synthesis of dolichyl-phosphate-glucose TAS Homo sapiens 58367 R-HSA-5173005 https://reactome.org/PathwayBrowser/#/R-HSA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins TAS Homo sapiens 58367 R-HSA-5610038 https://reactome.org/PathwayBrowser/#/R-HSA-5610038 Defective GALT does not transfer UMP to Gal1P TAS Homo sapiens 58367 R-HSA-6785565 https://reactome.org/PathwayBrowser/#/R-HSA-6785565 Defective B3GALTL does not transfer glucose to O-fucosyl-proteins TAS Homo sapiens 58367 R-HSA-6810464 https://reactome.org/PathwayBrowser/#/R-HSA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP TAS Homo sapiens 58367 R-HSA-70286 https://reactome.org/PathwayBrowser/#/R-HSA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose TAS Homo sapiens 58367 R-HSA-70361 https://reactome.org/PathwayBrowser/#/R-HSA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal TAS Homo sapiens 58367 R-HSA-70369 https://reactome.org/PathwayBrowser/#/R-HSA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc TAS Homo sapiens 58367 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 58367 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 58367 R-HSA-9792608 https://reactome.org/PathwayBrowser/#/R-HSA-9792608 SLC35D2 exchanges UDP-D-glucose for UMP TAS Homo sapiens 58367 R-MMU-1638104 https://reactome.org/PathwayBrowser/#/R-MMU-1638104 UGCG transfers glucose to ceramide IEA Mus musculus 58367 R-MMU-173597 https://reactome.org/PathwayBrowser/#/R-MMU-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Mus musculus 58367 R-MMU-1981157 https://reactome.org/PathwayBrowser/#/R-MMU-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Mus musculus 58367 R-MMU-2023179 https://reactome.org/PathwayBrowser/#/R-MMU-2023179 Glucosylation of Pre-Notch by Poglut1 TAS Mus musculus 58367 R-MMU-3322001 https://reactome.org/PathwayBrowser/#/R-MMU-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Mus musculus 58367 R-MMU-3322003 https://reactome.org/PathwayBrowser/#/R-MMU-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Mus musculus 58367 R-MMU-3322025 https://reactome.org/PathwayBrowser/#/R-MMU-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Mus musculus 58367 R-MMU-3322041 https://reactome.org/PathwayBrowser/#/R-MMU-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Mus musculus 58367 R-MMU-3781024 https://reactome.org/PathwayBrowser/#/R-MMU-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Mus musculus 58367 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 58367 R-MMU-417858 https://reactome.org/PathwayBrowser/#/R-MMU-417858 P2Y14 receptor can bind to UDP-glucose IEA Mus musculus 58367 R-MMU-446214 https://reactome.org/PathwayBrowser/#/R-MMU-446214 Synthesis of dolichyl-phosphate-glucose IEA Mus musculus 58367 R-MMU-5173005 https://reactome.org/PathwayBrowser/#/R-MMU-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Mus musculus 58367 R-MMU-6810464 https://reactome.org/PathwayBrowser/#/R-MMU-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Mus musculus 58367 R-MMU-70286 https://reactome.org/PathwayBrowser/#/R-MMU-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Mus musculus 58367 R-MMU-70361 https://reactome.org/PathwayBrowser/#/R-MMU-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Mus musculus 58367 R-MMU-70369 https://reactome.org/PathwayBrowser/#/R-MMU-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Mus musculus 58367 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 58367 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 58367 R-MMU-9792608 https://reactome.org/PathwayBrowser/#/R-MMU-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Mus musculus 58367 R-MTU-868622 https://reactome.org/PathwayBrowser/#/R-MTU-868622 Glucose is transferred from UDP-glucose onto glucose-6-phosphate TAS Mycobacterium tuberculosis 58367 R-RNO-1638104 https://reactome.org/PathwayBrowser/#/R-RNO-1638104 UGCG transfers glucose to ceramide IEA Rattus norvegicus 58367 R-RNO-173597 https://reactome.org/PathwayBrowser/#/R-RNO-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Rattus norvegicus 58367 R-RNO-1981157 https://reactome.org/PathwayBrowser/#/R-RNO-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Rattus norvegicus 58367 R-RNO-3322001 https://reactome.org/PathwayBrowser/#/R-RNO-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Rattus norvegicus 58367 R-RNO-3322003 https://reactome.org/PathwayBrowser/#/R-RNO-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Rattus norvegicus 58367 R-RNO-3322025 https://reactome.org/PathwayBrowser/#/R-RNO-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Rattus norvegicus 58367 R-RNO-3322041 https://reactome.org/PathwayBrowser/#/R-RNO-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Rattus norvegicus 58367 R-RNO-3781024 https://reactome.org/PathwayBrowser/#/R-RNO-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Rattus norvegicus 58367 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 58367 R-RNO-417858 https://reactome.org/PathwayBrowser/#/R-RNO-417858 P2Y14 receptor can bind to UDP-glucose IEA Rattus norvegicus 58367 R-RNO-446214 https://reactome.org/PathwayBrowser/#/R-RNO-446214 Synthesis of dolichyl-phosphate-glucose IEA Rattus norvegicus 58367 R-RNO-5173005 https://reactome.org/PathwayBrowser/#/R-RNO-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Rattus norvegicus 58367 R-RNO-6810464 https://reactome.org/PathwayBrowser/#/R-RNO-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Rattus norvegicus 58367 R-RNO-70286 https://reactome.org/PathwayBrowser/#/R-RNO-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Rattus norvegicus 58367 R-RNO-70361 https://reactome.org/PathwayBrowser/#/R-RNO-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Rattus norvegicus 58367 R-RNO-70369 https://reactome.org/PathwayBrowser/#/R-RNO-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Rattus norvegicus 58367 R-RNO-9792608 https://reactome.org/PathwayBrowser/#/R-RNO-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Rattus norvegicus 58367 R-SCE-3322001 https://reactome.org/PathwayBrowser/#/R-SCE-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Saccharomyces cerevisiae 58367 R-SCE-3322003 https://reactome.org/PathwayBrowser/#/R-SCE-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Saccharomyces cerevisiae 58367 R-SCE-3322009 https://reactome.org/PathwayBrowser/#/R-SCE-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Saccharomyces cerevisiae 58367 R-SCE-3322014 https://reactome.org/PathwayBrowser/#/R-SCE-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Saccharomyces cerevisiae 58367 R-SCE-3322019 https://reactome.org/PathwayBrowser/#/R-SCE-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Saccharomyces cerevisiae 58367 R-SCE-3322025 https://reactome.org/PathwayBrowser/#/R-SCE-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Saccharomyces cerevisiae 58367 R-SCE-3322041 https://reactome.org/PathwayBrowser/#/R-SCE-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Saccharomyces cerevisiae 58367 R-SCE-3780994 https://reactome.org/PathwayBrowser/#/R-SCE-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Saccharomyces cerevisiae 58367 R-SCE-3781024 https://reactome.org/PathwayBrowser/#/R-SCE-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Saccharomyces cerevisiae 58367 R-SCE-446214 https://reactome.org/PathwayBrowser/#/R-SCE-446214 Synthesis of dolichyl-phosphate-glucose IEA Saccharomyces cerevisiae 58367 R-SCE-70286 https://reactome.org/PathwayBrowser/#/R-SCE-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Saccharomyces cerevisiae 58367 R-SCE-70369 https://reactome.org/PathwayBrowser/#/R-SCE-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Saccharomyces cerevisiae 58367 R-SPO-446214 https://reactome.org/PathwayBrowser/#/R-SPO-446214 Synthesis of dolichyl-phosphate-glucose IEA Schizosaccharomyces pombe 58367 R-SPO-70286 https://reactome.org/PathwayBrowser/#/R-SPO-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Schizosaccharomyces pombe 58367 R-SPO-70369 https://reactome.org/PathwayBrowser/#/R-SPO-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Schizosaccharomyces pombe 58367 R-SSC-1638104 https://reactome.org/PathwayBrowser/#/R-SSC-1638104 UGCG transfers glucose to ceramide IEA Sus scrofa 58367 R-SSC-173597 https://reactome.org/PathwayBrowser/#/R-SSC-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Sus scrofa 58367 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa 58367 R-SSC-3322001 https://reactome.org/PathwayBrowser/#/R-SSC-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Sus scrofa 58367 R-SSC-3322003 https://reactome.org/PathwayBrowser/#/R-SSC-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Sus scrofa 58367 R-SSC-3322009 https://reactome.org/PathwayBrowser/#/R-SSC-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Sus scrofa 58367 R-SSC-3322014 https://reactome.org/PathwayBrowser/#/R-SSC-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Sus scrofa 58367 R-SSC-3322019 https://reactome.org/PathwayBrowser/#/R-SSC-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Sus scrofa 58367 R-SSC-3322025 https://reactome.org/PathwayBrowser/#/R-SSC-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Sus scrofa 58367 R-SSC-3322041 https://reactome.org/PathwayBrowser/#/R-SSC-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Sus scrofa 58367 R-SSC-3780994 https://reactome.org/PathwayBrowser/#/R-SSC-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Sus scrofa 58367 R-SSC-3781024 https://reactome.org/PathwayBrowser/#/R-SSC-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Sus scrofa 58367 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 58367 R-SSC-417858 https://reactome.org/PathwayBrowser/#/R-SSC-417858 P2Y14 receptor can bind to UDP-glucose IEA Sus scrofa 58367 R-SSC-446214 https://reactome.org/PathwayBrowser/#/R-SSC-446214 Synthesis of dolichyl-phosphate-glucose IEA Sus scrofa 58367 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa 58367 R-SSC-6810464 https://reactome.org/PathwayBrowser/#/R-SSC-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Sus scrofa 58367 R-SSC-70286 https://reactome.org/PathwayBrowser/#/R-SSC-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Sus scrofa 58367 R-SSC-70361 https://reactome.org/PathwayBrowser/#/R-SSC-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Sus scrofa 58367 R-SSC-70369 https://reactome.org/PathwayBrowser/#/R-SSC-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Sus scrofa 58367 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 58367 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 58367 R-SSC-9792608 https://reactome.org/PathwayBrowser/#/R-SSC-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Sus scrofa 58367 R-XTR-1638104 https://reactome.org/PathwayBrowser/#/R-XTR-1638104 UGCG transfers glucose to ceramide IEA Xenopus tropicalis 58367 R-XTR-173597 https://reactome.org/PathwayBrowser/#/R-XTR-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Xenopus tropicalis 58367 R-XTR-1981157 https://reactome.org/PathwayBrowser/#/R-XTR-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Xenopus tropicalis 58367 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 58367 R-XTR-417858 https://reactome.org/PathwayBrowser/#/R-XTR-417858 P2Y14 receptor can bind to UDP-glucose IEA Xenopus tropicalis 58367 R-XTR-446214 https://reactome.org/PathwayBrowser/#/R-XTR-446214 Synthesis of dolichyl-phosphate-glucose IEA Xenopus tropicalis 58367 R-XTR-5173005 https://reactome.org/PathwayBrowser/#/R-XTR-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Xenopus tropicalis 58367 R-XTR-70286 https://reactome.org/PathwayBrowser/#/R-XTR-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose IEA Xenopus tropicalis 58367 R-XTR-70369 https://reactome.org/PathwayBrowser/#/R-XTR-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Xenopus tropicalis 58367 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 58367 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 58367 R-XTR-9792608 https://reactome.org/PathwayBrowser/#/R-XTR-9792608 SLC35D2 exchanges UDP-D-glucose for UMP IEA Xenopus tropicalis 58369 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 58369 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 58369 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 58369 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 58369 R-BTA-73635 https://reactome.org/PathwayBrowser/#/R-BTA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Bos taurus 58369 R-BTA-75126 https://reactome.org/PathwayBrowser/#/R-BTA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Bos taurus 58369 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 58369 R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 58369 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 58369 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 58369 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 58369 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 58369 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 58369 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 58369 R-CEL-73635 https://reactome.org/PathwayBrowser/#/R-CEL-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Caenorhabditis elegans 58369 R-CEL-75126 https://reactome.org/PathwayBrowser/#/R-CEL-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Caenorhabditis elegans 58369 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 58369 R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 58369 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 58369 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 58369 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 58369 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 58369 R-CFA-73635 https://reactome.org/PathwayBrowser/#/R-CFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Canis familiaris 58369 R-CFA-75126 https://reactome.org/PathwayBrowser/#/R-CFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Canis familiaris 58369 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58369 R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58369 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 58369 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 58369 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 58369 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 58369 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 58369 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 58369 R-DDI-73635 https://reactome.org/PathwayBrowser/#/R-DDI-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Dictyostelium discoideum 58369 R-DDI-75126 https://reactome.org/PathwayBrowser/#/R-DDI-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Dictyostelium discoideum 58369 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 58369 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 58369 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 58369 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 58369 R-DME-73635 https://reactome.org/PathwayBrowser/#/R-DME-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Drosophila melanogaster 58369 R-DME-75126 https://reactome.org/PathwayBrowser/#/R-DME-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Drosophila melanogaster 58369 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 58369 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 58369 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 58369 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 58369 R-DRE-73635 https://reactome.org/PathwayBrowser/#/R-DRE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Danio rerio 58369 R-DRE-75126 https://reactome.org/PathwayBrowser/#/R-DRE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Danio rerio 58369 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 58369 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 58369 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 58369 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 58369 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 58369 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 58369 R-GGA-73635 https://reactome.org/PathwayBrowser/#/R-GGA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Gallus gallus 58369 R-GGA-75126 https://reactome.org/PathwayBrowser/#/R-GGA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Gallus gallus 58369 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58369 R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58369 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 58369 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 58369 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 58369 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 58369 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 58369 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 58369 R-HSA-73635 https://reactome.org/PathwayBrowser/#/R-HSA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] TAS Homo sapiens 58369 R-HSA-75126 https://reactome.org/PathwayBrowser/#/R-HSA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] TAS Homo sapiens 58369 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58369 R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58369 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 58369 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 58369 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 58369 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 58369 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 58369 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 58369 R-MMU-73635 https://reactome.org/PathwayBrowser/#/R-MMU-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Mus musculus 58369 R-MMU-75126 https://reactome.org/PathwayBrowser/#/R-MMU-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Mus musculus 58369 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 58369 R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 58369 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 58369 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 58369 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 58369 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 58369 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 58369 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 58369 R-PFA-73635 https://reactome.org/PathwayBrowser/#/R-PFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Plasmodium falciparum 58369 R-PFA-75126 https://reactome.org/PathwayBrowser/#/R-PFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Plasmodium falciparum 58369 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 58369 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 58369 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 58369 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 58369 R-RNO-73635 https://reactome.org/PathwayBrowser/#/R-RNO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Rattus norvegicus 58369 R-RNO-75126 https://reactome.org/PathwayBrowser/#/R-RNO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Rattus norvegicus 58369 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58369 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58369 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 58369 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 58369 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 58369 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 58369 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 58369 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 58369 R-SCE-73635 https://reactome.org/PathwayBrowser/#/R-SCE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Saccharomyces cerevisiae 58369 R-SCE-75126 https://reactome.org/PathwayBrowser/#/R-SCE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Saccharomyces cerevisiae 58369 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 58369 R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 58369 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 58369 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 58369 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 58369 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 58369 R-SPO-73635 https://reactome.org/PathwayBrowser/#/R-SPO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Schizosaccharomyces pombe 58369 R-SPO-75126 https://reactome.org/PathwayBrowser/#/R-SPO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Schizosaccharomyces pombe 58369 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 58369 R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 58369 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 58369 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 58369 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 58369 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 58369 R-SSC-73635 https://reactome.org/PathwayBrowser/#/R-SSC-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Sus scrofa 58369 R-SSC-75126 https://reactome.org/PathwayBrowser/#/R-SSC-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Sus scrofa 58369 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58369 R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58369 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 58369 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 58369 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 58369 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 58369 R-XTR-73635 https://reactome.org/PathwayBrowser/#/R-XTR-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Xenopus tropicalis 58369 R-XTR-75126 https://reactome.org/PathwayBrowser/#/R-XTR-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Xenopus tropicalis 58369 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58369 R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58369 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 58369 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 58373 R-SCE-2162292 https://reactome.org/PathwayBrowser/#/R-SCE-2162292 HHB is hydroxylated to DHHB by Coq6 TAS Saccharomyces cerevisiae 58388 R-BTA-382054 https://reactome.org/PathwayBrowser/#/R-BTA-382054 PDGF binds to extracellular matrix proteins IEA Bos taurus 58388 R-CEL-382054 https://reactome.org/PathwayBrowser/#/R-CEL-382054 PDGF binds to extracellular matrix proteins IEA Caenorhabditis elegans 58388 R-CFA-382054 https://reactome.org/PathwayBrowser/#/R-CFA-382054 PDGF binds to extracellular matrix proteins IEA Canis familiaris 58388 R-GGA-382054 https://reactome.org/PathwayBrowser/#/R-GGA-382054 PDGF binds to extracellular matrix proteins IEA Gallus gallus 58388 R-HSA-382054 https://reactome.org/PathwayBrowser/#/R-HSA-382054 PDGF binds to extracellular matrix proteins TAS Homo sapiens 58388 R-MMU-382054 https://reactome.org/PathwayBrowser/#/R-MMU-382054 PDGF binds to extracellular matrix proteins IEA Mus musculus 58388 R-RNO-382054 https://reactome.org/PathwayBrowser/#/R-RNO-382054 PDGF binds to extracellular matrix proteins IEA Rattus norvegicus 58388 R-SSC-382054 https://reactome.org/PathwayBrowser/#/R-SSC-382054 PDGF binds to extracellular matrix proteins IEA Sus scrofa 58388 R-XTR-382054 https://reactome.org/PathwayBrowser/#/R-XTR-382054 PDGF binds to extracellular matrix proteins IEA Xenopus tropicalis 58394 R-MTU-964912 https://reactome.org/PathwayBrowser/#/R-MTU-964912 DHAP from Ery4P and PEP TAS Mycobacterium tuberculosis 58394 R-MTU-964914 https://reactome.org/PathwayBrowser/#/R-MTU-964914 DHQ from DAHP dephosphorylation TAS Mycobacterium tuberculosis 58402 R-BTA-1247922 https://reactome.org/PathwayBrowser/#/R-BTA-1247922 GGCT transforms gGluCys to OPRO IEA Bos taurus 58402 R-BTA-1247935 https://reactome.org/PathwayBrowser/#/R-BTA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Bos taurus 58402 R-BTA-6785928 https://reactome.org/PathwayBrowser/#/R-BTA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Bos taurus 58402 R-CEL-1247922 https://reactome.org/PathwayBrowser/#/R-CEL-1247922 GGCT transforms gGluCys to OPRO IEA Caenorhabditis elegans 58402 R-CEL-1247935 https://reactome.org/PathwayBrowser/#/R-CEL-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Caenorhabditis elegans 58402 R-CEL-6785928 https://reactome.org/PathwayBrowser/#/R-CEL-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Caenorhabditis elegans 58402 R-CFA-1247922 https://reactome.org/PathwayBrowser/#/R-CFA-1247922 GGCT transforms gGluCys to OPRO IEA Canis familiaris 58402 R-CFA-1247935 https://reactome.org/PathwayBrowser/#/R-CFA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Canis familiaris 58402 R-CFA-6785928 https://reactome.org/PathwayBrowser/#/R-CFA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Canis familiaris 58402 R-DDI-1247935 https://reactome.org/PathwayBrowser/#/R-DDI-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Dictyostelium discoideum 58402 R-DDI-6785928 https://reactome.org/PathwayBrowser/#/R-DDI-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Dictyostelium discoideum 58402 R-DME-1247922 https://reactome.org/PathwayBrowser/#/R-DME-1247922 GGCT transforms gGluCys to OPRO IEA Drosophila melanogaster 58402 R-DME-1247935 https://reactome.org/PathwayBrowser/#/R-DME-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Drosophila melanogaster 58402 R-DME-6785928 https://reactome.org/PathwayBrowser/#/R-DME-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Drosophila melanogaster 58402 R-DRE-1247922 https://reactome.org/PathwayBrowser/#/R-DRE-1247922 GGCT transforms gGluCys to OPRO IEA Danio rerio 58402 R-DRE-1247935 https://reactome.org/PathwayBrowser/#/R-DRE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Danio rerio 58402 R-DRE-6785928 https://reactome.org/PathwayBrowser/#/R-DRE-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Danio rerio 58402 R-GGA-1247922 https://reactome.org/PathwayBrowser/#/R-GGA-1247922 GGCT transforms gGluCys to OPRO IEA Gallus gallus 58402 R-GGA-6785928 https://reactome.org/PathwayBrowser/#/R-GGA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Gallus gallus 58402 R-HSA-1247922 https://reactome.org/PathwayBrowser/#/R-HSA-1247922 GGCT transforms gGluCys to OPRO TAS Homo sapiens 58402 R-HSA-1247935 https://reactome.org/PathwayBrowser/#/R-HSA-1247935 OPLAH hydrolyses OPRO to L-Glu TAS Homo sapiens 58402 R-HSA-5603208 https://reactome.org/PathwayBrowser/#/R-HSA-5603208 Defective OPLAH does not hydrolyse OPRO TAS Homo sapiens 58402 R-HSA-6785928 https://reactome.org/PathwayBrowser/#/R-HSA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly TAS Homo sapiens 58402 R-MMU-1247922 https://reactome.org/PathwayBrowser/#/R-MMU-1247922 GGCT transforms gGluCys to OPRO IEA Mus musculus 58402 R-MMU-1247935 https://reactome.org/PathwayBrowser/#/R-MMU-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Mus musculus 58402 R-MMU-6785928 https://reactome.org/PathwayBrowser/#/R-MMU-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Mus musculus 58402 R-RNO-1247922 https://reactome.org/PathwayBrowser/#/R-RNO-1247922 GGCT transforms gGluCys to OPRO IEA Rattus norvegicus 58402 R-RNO-1247935 https://reactome.org/PathwayBrowser/#/R-RNO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Rattus norvegicus 58402 R-RNO-6785928 https://reactome.org/PathwayBrowser/#/R-RNO-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Rattus norvegicus 58402 R-SCE-1247935 https://reactome.org/PathwayBrowser/#/R-SCE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Saccharomyces cerevisiae 58402 R-SCE-6785928 https://reactome.org/PathwayBrowser/#/R-SCE-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Saccharomyces cerevisiae 58402 R-SPO-1247935 https://reactome.org/PathwayBrowser/#/R-SPO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Schizosaccharomyces pombe 58402 R-SPO-6785928 https://reactome.org/PathwayBrowser/#/R-SPO-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Schizosaccharomyces pombe 58402 R-SSC-1247922 https://reactome.org/PathwayBrowser/#/R-SSC-1247922 GGCT transforms gGluCys to OPRO IEA Sus scrofa 58402 R-SSC-1247935 https://reactome.org/PathwayBrowser/#/R-SSC-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Sus scrofa 58402 R-SSC-6785928 https://reactome.org/PathwayBrowser/#/R-SSC-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Sus scrofa 58402 R-XTR-1247922 https://reactome.org/PathwayBrowser/#/R-XTR-1247922 GGCT transforms gGluCys to OPRO IEA Xenopus tropicalis 58402 R-XTR-1247935 https://reactome.org/PathwayBrowser/#/R-XTR-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Xenopus tropicalis 58402 R-XTR-6785928 https://reactome.org/PathwayBrowser/#/R-XTR-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Xenopus tropicalis 58414 R-BTA-1855171 https://reactome.org/PathwayBrowser/#/R-BTA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Bos taurus 58414 R-BTA-1855172 https://reactome.org/PathwayBrowser/#/R-BTA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Bos taurus 58414 R-BTA-1855180 https://reactome.org/PathwayBrowser/#/R-BTA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Bos taurus 58414 R-BTA-1855197 https://reactome.org/PathwayBrowser/#/R-BTA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Bos taurus 58414 R-BTA-1855213 https://reactome.org/PathwayBrowser/#/R-BTA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Bos taurus 58414 R-BTA-1855218 https://reactome.org/PathwayBrowser/#/R-BTA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Bos taurus 58414 R-BTA-1855232 https://reactome.org/PathwayBrowser/#/R-BTA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Bos taurus 58414 R-BTA-2267372 https://reactome.org/PathwayBrowser/#/R-BTA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Bos taurus 58414 R-BTA-994140 https://reactome.org/PathwayBrowser/#/R-BTA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Bos taurus 58414 R-CEL-1855180 https://reactome.org/PathwayBrowser/#/R-CEL-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Caenorhabditis elegans 58414 R-CEL-1855213 https://reactome.org/PathwayBrowser/#/R-CEL-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Caenorhabditis elegans 58414 R-CEL-1855218 https://reactome.org/PathwayBrowser/#/R-CEL-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Caenorhabditis elegans 58414 R-CFA-1855171 https://reactome.org/PathwayBrowser/#/R-CFA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Canis familiaris 58414 R-CFA-1855172 https://reactome.org/PathwayBrowser/#/R-CFA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Canis familiaris 58414 R-CFA-1855180 https://reactome.org/PathwayBrowser/#/R-CFA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Canis familiaris 58414 R-CFA-1855197 https://reactome.org/PathwayBrowser/#/R-CFA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 58414 R-CFA-1855213 https://reactome.org/PathwayBrowser/#/R-CFA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Canis familiaris 58414 R-CFA-1855218 https://reactome.org/PathwayBrowser/#/R-CFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Canis familiaris 58414 R-CFA-1855232 https://reactome.org/PathwayBrowser/#/R-CFA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Canis familiaris 58414 R-CFA-2267372 https://reactome.org/PathwayBrowser/#/R-CFA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Canis familiaris 58414 R-CFA-994140 https://reactome.org/PathwayBrowser/#/R-CFA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Canis familiaris 58414 R-DDI-1855171 https://reactome.org/PathwayBrowser/#/R-DDI-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 58414 R-DDI-1855172 https://reactome.org/PathwayBrowser/#/R-DDI-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 58414 R-DDI-1855197 https://reactome.org/PathwayBrowser/#/R-DDI-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 58414 R-DDI-1855213 https://reactome.org/PathwayBrowser/#/R-DDI-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Dictyostelium discoideum 58414 R-DDI-1855218 https://reactome.org/PathwayBrowser/#/R-DDI-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Dictyostelium discoideum 58414 R-DDI-1855232 https://reactome.org/PathwayBrowser/#/R-DDI-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Dictyostelium discoideum 58414 R-DDI-2267372 https://reactome.org/PathwayBrowser/#/R-DDI-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Dictyostelium discoideum 58414 R-DDI-994140 https://reactome.org/PathwayBrowser/#/R-DDI-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Dictyostelium discoideum 58414 R-DME-1855180 https://reactome.org/PathwayBrowser/#/R-DME-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Drosophila melanogaster 58414 R-DME-1855213 https://reactome.org/PathwayBrowser/#/R-DME-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Drosophila melanogaster 58414 R-DME-1855218 https://reactome.org/PathwayBrowser/#/R-DME-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Drosophila melanogaster 58414 R-DME-1855232 https://reactome.org/PathwayBrowser/#/R-DME-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Drosophila melanogaster 58414 R-DRE-1855171 https://reactome.org/PathwayBrowser/#/R-DRE-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Danio rerio 58414 R-DRE-1855172 https://reactome.org/PathwayBrowser/#/R-DRE-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Danio rerio 58414 R-DRE-1855180 https://reactome.org/PathwayBrowser/#/R-DRE-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Danio rerio 58414 R-DRE-1855197 https://reactome.org/PathwayBrowser/#/R-DRE-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Danio rerio 58414 R-DRE-1855218 https://reactome.org/PathwayBrowser/#/R-DRE-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Danio rerio 58414 R-DRE-2267372 https://reactome.org/PathwayBrowser/#/R-DRE-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Danio rerio 58414 R-DRE-994140 https://reactome.org/PathwayBrowser/#/R-DRE-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Danio rerio 58414 R-GGA-1855171 https://reactome.org/PathwayBrowser/#/R-GGA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Gallus gallus 58414 R-GGA-1855172 https://reactome.org/PathwayBrowser/#/R-GGA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Gallus gallus 58414 R-GGA-1855180 https://reactome.org/PathwayBrowser/#/R-GGA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Gallus gallus 58414 R-GGA-1855197 https://reactome.org/PathwayBrowser/#/R-GGA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 58414 R-GGA-1855213 https://reactome.org/PathwayBrowser/#/R-GGA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Gallus gallus 58414 R-GGA-1855218 https://reactome.org/PathwayBrowser/#/R-GGA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Gallus gallus 58414 R-GGA-1855232 https://reactome.org/PathwayBrowser/#/R-GGA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Gallus gallus 58414 R-GGA-2267372 https://reactome.org/PathwayBrowser/#/R-GGA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Gallus gallus 58414 R-GGA-994140 https://reactome.org/PathwayBrowser/#/R-GGA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Gallus gallus 58414 R-HSA-1855171 https://reactome.org/PathwayBrowser/#/R-HSA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol TAS Homo sapiens 58414 R-HSA-1855172 https://reactome.org/PathwayBrowser/#/R-HSA-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol TAS Homo sapiens 58414 R-HSA-1855180 https://reactome.org/PathwayBrowser/#/R-HSA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol TAS Homo sapiens 58414 R-HSA-1855197 https://reactome.org/PathwayBrowser/#/R-HSA-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 58414 R-HSA-1855213 https://reactome.org/PathwayBrowser/#/R-HSA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane TAS Homo sapiens 58414 R-HSA-1855218 https://reactome.org/PathwayBrowser/#/R-HSA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol TAS Homo sapiens 58414 R-HSA-1855232 https://reactome.org/PathwayBrowser/#/R-HSA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol TAS Homo sapiens 58414 R-HSA-2267372 https://reactome.org/PathwayBrowser/#/R-HSA-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 TAS Homo sapiens 58414 R-HSA-994140 https://reactome.org/PathwayBrowser/#/R-HSA-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 TAS Homo sapiens 58414 R-MMU-1855171 https://reactome.org/PathwayBrowser/#/R-MMU-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Mus musculus 58414 R-MMU-1855172 https://reactome.org/PathwayBrowser/#/R-MMU-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Mus musculus 58414 R-MMU-1855180 https://reactome.org/PathwayBrowser/#/R-MMU-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Mus musculus 58414 R-MMU-1855197 https://reactome.org/PathwayBrowser/#/R-MMU-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Mus musculus 58414 R-MMU-1855213 https://reactome.org/PathwayBrowser/#/R-MMU-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Mus musculus 58414 R-MMU-1855218 https://reactome.org/PathwayBrowser/#/R-MMU-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Mus musculus 58414 R-MMU-1855232 https://reactome.org/PathwayBrowser/#/R-MMU-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Mus musculus 58414 R-MMU-2267372 https://reactome.org/PathwayBrowser/#/R-MMU-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Mus musculus 58414 R-MMU-994140 https://reactome.org/PathwayBrowser/#/R-MMU-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Mus musculus 58414 R-PFA-1855213 https://reactome.org/PathwayBrowser/#/R-PFA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Plasmodium falciparum 58414 R-PFA-1855218 https://reactome.org/PathwayBrowser/#/R-PFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Plasmodium falciparum 58414 R-RNO-1855171 https://reactome.org/PathwayBrowser/#/R-RNO-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 58414 R-RNO-1855172 https://reactome.org/PathwayBrowser/#/R-RNO-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 58414 R-RNO-1855180 https://reactome.org/PathwayBrowser/#/R-RNO-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Rattus norvegicus 58414 R-RNO-1855197 https://reactome.org/PathwayBrowser/#/R-RNO-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 58414 R-RNO-1855213 https://reactome.org/PathwayBrowser/#/R-RNO-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Rattus norvegicus 58414 R-RNO-1855218 https://reactome.org/PathwayBrowser/#/R-RNO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Rattus norvegicus 58414 R-RNO-1855232 https://reactome.org/PathwayBrowser/#/R-RNO-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Rattus norvegicus 58414 R-RNO-2267372 https://reactome.org/PathwayBrowser/#/R-RNO-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Rattus norvegicus 58414 R-RNO-994140 https://reactome.org/PathwayBrowser/#/R-RNO-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Rattus norvegicus 58414 R-SCE-1855218 https://reactome.org/PathwayBrowser/#/R-SCE-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Saccharomyces cerevisiae 58414 R-SPO-1855213 https://reactome.org/PathwayBrowser/#/R-SPO-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Schizosaccharomyces pombe 58414 R-SPO-1855218 https://reactome.org/PathwayBrowser/#/R-SPO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Schizosaccharomyces pombe 58414 R-SSC-1855171 https://reactome.org/PathwayBrowser/#/R-SSC-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Sus scrofa 58414 R-SSC-1855172 https://reactome.org/PathwayBrowser/#/R-SSC-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Sus scrofa 58414 R-SSC-1855180 https://reactome.org/PathwayBrowser/#/R-SSC-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Sus scrofa 58414 R-SSC-1855197 https://reactome.org/PathwayBrowser/#/R-SSC-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 58414 R-SSC-1855213 https://reactome.org/PathwayBrowser/#/R-SSC-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Sus scrofa 58414 R-SSC-1855218 https://reactome.org/PathwayBrowser/#/R-SSC-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Sus scrofa 58414 R-SSC-1855232 https://reactome.org/PathwayBrowser/#/R-SSC-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Sus scrofa 58414 R-SSC-2267372 https://reactome.org/PathwayBrowser/#/R-SSC-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Sus scrofa 58414 R-SSC-994140 https://reactome.org/PathwayBrowser/#/R-SSC-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Sus scrofa 58414 R-XTR-1855171 https://reactome.org/PathwayBrowser/#/R-XTR-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 58414 R-XTR-1855172 https://reactome.org/PathwayBrowser/#/R-XTR-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 58414 R-XTR-1855180 https://reactome.org/PathwayBrowser/#/R-XTR-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Xenopus tropicalis 58414 R-XTR-1855197 https://reactome.org/PathwayBrowser/#/R-XTR-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 58414 R-XTR-1855213 https://reactome.org/PathwayBrowser/#/R-XTR-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Xenopus tropicalis 58414 R-XTR-1855218 https://reactome.org/PathwayBrowser/#/R-XTR-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Xenopus tropicalis 58414 R-XTR-2267372 https://reactome.org/PathwayBrowser/#/R-XTR-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Xenopus tropicalis 58414 R-XTR-994140 https://reactome.org/PathwayBrowser/#/R-XTR-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Xenopus tropicalis 58419 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 58419 R-BTA-6784224 https://reactome.org/PathwayBrowser/#/R-BTA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Bos taurus 58419 R-BTA-8955817 https://reactome.org/PathwayBrowser/#/R-BTA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Bos taurus 58419 R-CEL-6784224 https://reactome.org/PathwayBrowser/#/R-CEL-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Caenorhabditis elegans 58419 R-CEL-8955817 https://reactome.org/PathwayBrowser/#/R-CEL-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Caenorhabditis elegans 58419 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 58419 R-CFA-6784224 https://reactome.org/PathwayBrowser/#/R-CFA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Canis familiaris 58419 R-CFA-8955817 https://reactome.org/PathwayBrowser/#/R-CFA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Canis familiaris 58419 R-DDI-6784224 https://reactome.org/PathwayBrowser/#/R-DDI-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Dictyostelium discoideum 58419 R-DDI-8955817 https://reactome.org/PathwayBrowser/#/R-DDI-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Dictyostelium discoideum 58419 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 58419 R-DME-6784224 https://reactome.org/PathwayBrowser/#/R-DME-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Drosophila melanogaster 58419 R-DME-8955817 https://reactome.org/PathwayBrowser/#/R-DME-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Drosophila melanogaster 58419 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 58419 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 58419 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 58419 R-HSA-6784213 https://reactome.org/PathwayBrowser/#/R-HSA-6784213 Unknown hydroxyproline carrier transports cytosolic HPRO into the mitochondrial matrix TAS Homo sapiens 58419 R-HSA-6784224 https://reactome.org/PathwayBrowser/#/R-HSA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate TAS Homo sapiens 58419 R-HSA-8955817 https://reactome.org/PathwayBrowser/#/R-HSA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH TAS Homo sapiens 58419 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 58419 R-MMU-6784224 https://reactome.org/PathwayBrowser/#/R-MMU-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Mus musculus 58419 R-MMU-8955817 https://reactome.org/PathwayBrowser/#/R-MMU-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Mus musculus 58419 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 58419 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 58419 R-RNO-6784224 https://reactome.org/PathwayBrowser/#/R-RNO-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Rattus norvegicus 58419 R-RNO-8955817 https://reactome.org/PathwayBrowser/#/R-RNO-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Rattus norvegicus 58419 R-SCE-6784224 https://reactome.org/PathwayBrowser/#/R-SCE-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Saccharomyces cerevisiae 58419 R-SCE-8955817 https://reactome.org/PathwayBrowser/#/R-SCE-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Saccharomyces cerevisiae 58419 R-SPO-6784224 https://reactome.org/PathwayBrowser/#/R-SPO-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Schizosaccharomyces pombe 58419 R-SPO-8955817 https://reactome.org/PathwayBrowser/#/R-SPO-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Schizosaccharomyces pombe 58419 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 58419 R-SSC-6784224 https://reactome.org/PathwayBrowser/#/R-SSC-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Sus scrofa 58419 R-SSC-8955817 https://reactome.org/PathwayBrowser/#/R-SSC-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Sus scrofa 58419 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 58419 R-XTR-6784224 https://reactome.org/PathwayBrowser/#/R-XTR-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Xenopus tropicalis 58419 R-XTR-8955817 https://reactome.org/PathwayBrowser/#/R-XTR-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH IEA Xenopus tropicalis 58432 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 58432 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 58432 R-BTA-390886 https://reactome.org/PathwayBrowser/#/R-BTA-390886 HRH4 binds Hist IEA Bos taurus 58432 R-BTA-390909 https://reactome.org/PathwayBrowser/#/R-BTA-390909 HRH2 binds hist IEA Bos taurus 58432 R-BTA-444160 https://reactome.org/PathwayBrowser/#/R-BTA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Bos taurus 58432 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 58432 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 58432 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 58432 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 58432 R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 58432 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 58432 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 58432 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 58432 R-BTA-9692880 https://reactome.org/PathwayBrowser/#/R-BTA-9692880 HRH3 binds Hist IEA Bos taurus 58432 R-BTA-977301 https://reactome.org/PathwayBrowser/#/R-BTA-977301 Histidine is decarboxylated to histamine IEA Bos taurus 58432 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 58432 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 58432 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 58432 R-CEL-390886 https://reactome.org/PathwayBrowser/#/R-CEL-390886 HRH4 binds Hist IEA Caenorhabditis elegans 58432 R-CEL-390909 https://reactome.org/PathwayBrowser/#/R-CEL-390909 HRH2 binds hist IEA Caenorhabditis elegans 58432 R-CEL-390912 https://reactome.org/PathwayBrowser/#/R-CEL-390912 HRH1 binds hist IEA Caenorhabditis elegans 58432 R-CEL-444160 https://reactome.org/PathwayBrowser/#/R-CEL-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Caenorhabditis elegans 58432 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 58432 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 58432 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 58432 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 58432 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 58432 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 58432 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 58432 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 58432 R-CEL-9692880 https://reactome.org/PathwayBrowser/#/R-CEL-9692880 HRH3 binds Hist IEA Caenorhabditis elegans 58432 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 58432 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 58432 R-CFA-390886 https://reactome.org/PathwayBrowser/#/R-CFA-390886 HRH4 binds Hist IEA Canis familiaris 58432 R-CFA-390909 https://reactome.org/PathwayBrowser/#/R-CFA-390909 HRH2 binds hist IEA Canis familiaris 58432 R-CFA-390912 https://reactome.org/PathwayBrowser/#/R-CFA-390912 HRH1 binds hist IEA Canis familiaris 58432 R-CFA-444160 https://reactome.org/PathwayBrowser/#/R-CFA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Canis familiaris 58432 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 58432 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 58432 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 58432 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 58432 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 58432 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 58432 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 58432 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 58432 R-CFA-9692880 https://reactome.org/PathwayBrowser/#/R-CFA-9692880 HRH3 binds Hist IEA Canis familiaris 58432 R-CFA-977301 https://reactome.org/PathwayBrowser/#/R-CFA-977301 Histidine is decarboxylated to histamine IEA Canis familiaris 58432 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 58432 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 58432 R-DME-390886 https://reactome.org/PathwayBrowser/#/R-DME-390886 HRH4 binds Hist IEA Drosophila melanogaster 58432 R-DME-390909 https://reactome.org/PathwayBrowser/#/R-DME-390909 HRH2 binds hist IEA Drosophila melanogaster 58432 R-DME-444160 https://reactome.org/PathwayBrowser/#/R-DME-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Drosophila melanogaster 58432 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 58432 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 58432 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 58432 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 58432 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 58432 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 58432 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 58432 R-DME-9692880 https://reactome.org/PathwayBrowser/#/R-DME-9692880 HRH3 binds Hist IEA Drosophila melanogaster 58432 R-DME-977301 https://reactome.org/PathwayBrowser/#/R-DME-977301 Histidine is decarboxylated to histamine IEA Drosophila melanogaster 58432 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 58432 R-DRE-390909 https://reactome.org/PathwayBrowser/#/R-DRE-390909 HRH2 binds hist IEA Danio rerio 58432 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 58432 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 58432 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 58432 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 58432 R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 58432 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 58432 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 58432 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 58432 R-GGA-390886 https://reactome.org/PathwayBrowser/#/R-GGA-390886 HRH4 binds Hist IEA Gallus gallus 58432 R-GGA-390909 https://reactome.org/PathwayBrowser/#/R-GGA-390909 HRH2 binds hist IEA Gallus gallus 58432 R-GGA-390912 https://reactome.org/PathwayBrowser/#/R-GGA-390912 HRH1 binds hist IEA Gallus gallus 58432 R-GGA-444160 https://reactome.org/PathwayBrowser/#/R-GGA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Gallus gallus 58432 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 58432 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 58432 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 58432 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 58432 R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 58432 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 58432 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 58432 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 58432 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 58432 R-GGA-9692880 https://reactome.org/PathwayBrowser/#/R-GGA-9692880 HRH3 binds Hist IEA Gallus gallus 58432 R-GGA-977301 https://reactome.org/PathwayBrowser/#/R-GGA-977301 Histidine is decarboxylated to histamine IEA Gallus gallus 58432 R-HSA-175993 https://reactome.org/PathwayBrowser/#/R-HSA-175993 HNMT transfers CH3 group from AdoMet to Hist TAS Homo sapiens 58432 R-HSA-2408544 https://reactome.org/PathwayBrowser/#/R-HSA-2408544 AdoSeMet is converted to AdeSeHCys by MetTrans(1) IEA Homo sapiens 58432 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 58432 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 58432 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 58432 R-HSA-390886 https://reactome.org/PathwayBrowser/#/R-HSA-390886 HRH4 binds Hist TAS Homo sapiens 58432 R-HSA-390909 https://reactome.org/PathwayBrowser/#/R-HSA-390909 HRH2 binds hist TAS Homo sapiens 58432 R-HSA-390912 https://reactome.org/PathwayBrowser/#/R-HSA-390912 HRH1 binds hist TAS Homo sapiens 58432 R-HSA-444160 https://reactome.org/PathwayBrowser/#/R-HSA-444160 VMAT1/2 can mediate the transport of biogenic amines TAS Homo sapiens 58432 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 58432 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 58432 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 58432 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 58432 R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 58432 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 58432 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 58432 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 58432 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 58432 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 58432 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 58432 R-HSA-9692880 https://reactome.org/PathwayBrowser/#/R-HSA-9692880 HRH3 binds Hist TAS Homo sapiens 58432 R-HSA-977301 https://reactome.org/PathwayBrowser/#/R-HSA-977301 Histidine is decarboxylated to histamine TAS Homo sapiens 58432 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 58432 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 58432 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 58432 R-MMU-390886 https://reactome.org/PathwayBrowser/#/R-MMU-390886 HRH4 binds Hist IEA Mus musculus 58432 R-MMU-390909 https://reactome.org/PathwayBrowser/#/R-MMU-390909 HRH2 binds hist IEA Mus musculus 58432 R-MMU-390912 https://reactome.org/PathwayBrowser/#/R-MMU-390912 HRH1 binds hist IEA Mus musculus 58432 R-MMU-444160 https://reactome.org/PathwayBrowser/#/R-MMU-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Mus musculus 58432 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 58432 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 58432 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 58432 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 58432 R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 58432 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 58432 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 58432 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 58432 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 58432 R-MMU-9692880 https://reactome.org/PathwayBrowser/#/R-MMU-9692880 HRH3 binds Hist IEA Mus musculus 58432 R-MMU-977301 https://reactome.org/PathwayBrowser/#/R-MMU-977301 Histidine is decarboxylated to histamine IEA Mus musculus 58432 R-RNO-2408545 https://reactome.org/PathwayBrowser/#/R-RNO-2408545 AdoSeMet is converted to AdeSeHCys by MetTrans(2) TAS Rattus norvegicus 58432 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 58432 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 58432 R-RNO-390886 https://reactome.org/PathwayBrowser/#/R-RNO-390886 HRH4 binds Hist IEA Rattus norvegicus 58432 R-RNO-390909 https://reactome.org/PathwayBrowser/#/R-RNO-390909 HRH2 binds hist IEA Rattus norvegicus 58432 R-RNO-390912 https://reactome.org/PathwayBrowser/#/R-RNO-390912 HRH1 binds hist IEA Rattus norvegicus 58432 R-RNO-444160 https://reactome.org/PathwayBrowser/#/R-RNO-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Rattus norvegicus 58432 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 58432 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 58432 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 58432 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 58432 R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 58432 R-RNO-9692880 https://reactome.org/PathwayBrowser/#/R-RNO-9692880 HRH3 binds Hist IEA Rattus norvegicus 58432 R-RNO-977301 https://reactome.org/PathwayBrowser/#/R-RNO-977301 Histidine is decarboxylated to histamine IEA Rattus norvegicus 58432 R-SPO-444160 https://reactome.org/PathwayBrowser/#/R-SPO-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Schizosaccharomyces pombe 58432 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 58432 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 58432 R-SSC-390909 https://reactome.org/PathwayBrowser/#/R-SSC-390909 HRH2 binds hist IEA Sus scrofa 58432 R-SSC-390912 https://reactome.org/PathwayBrowser/#/R-SSC-390912 HRH1 binds hist IEA Sus scrofa 58432 R-SSC-444160 https://reactome.org/PathwayBrowser/#/R-SSC-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Sus scrofa 58432 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 58432 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 58432 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 58432 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 58432 R-SSC-5696131 https://reactome.org/PathwayBrowser/#/R-SSC-5696131 AOC1 deaminates Hist IEA Sus scrofa 58432 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 58432 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 58432 R-SSC-9692880 https://reactome.org/PathwayBrowser/#/R-SSC-9692880 HRH3 binds Hist IEA Sus scrofa 58432 R-SSC-977301 https://reactome.org/PathwayBrowser/#/R-SSC-977301 Histidine is decarboxylated to histamine IEA Sus scrofa 58432 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 58432 R-XTR-390909 https://reactome.org/PathwayBrowser/#/R-XTR-390909 HRH2 binds hist IEA Xenopus tropicalis 58432 R-XTR-390912 https://reactome.org/PathwayBrowser/#/R-XTR-390912 HRH1 binds hist IEA Xenopus tropicalis 58432 R-XTR-444160 https://reactome.org/PathwayBrowser/#/R-XTR-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Xenopus tropicalis 58432 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 58432 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 58432 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 58432 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 58432 R-XTR-5696131 https://reactome.org/PathwayBrowser/#/R-XTR-5696131 AOC1 deaminates Hist IEA Xenopus tropicalis 58432 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 58432 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 58432 R-XTR-977301 https://reactome.org/PathwayBrowser/#/R-XTR-977301 Histidine is decarboxylated to histamine IEA Xenopus tropicalis 58443 R-BTA-73800 https://reactome.org/PathwayBrowser/#/R-BTA-73800 SAICAR => AICAR + Fumarate IEA Bos taurus 58443 R-BTA-73805 https://reactome.org/PathwayBrowser/#/R-BTA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Bos taurus 58443 R-CEL-73800 https://reactome.org/PathwayBrowser/#/R-CEL-73800 SAICAR => AICAR + Fumarate IEA Caenorhabditis elegans 58443 R-CEL-73805 https://reactome.org/PathwayBrowser/#/R-CEL-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Caenorhabditis elegans 58443 R-CFA-73800 https://reactome.org/PathwayBrowser/#/R-CFA-73800 SAICAR => AICAR + Fumarate IEA Canis familiaris 58443 R-CFA-73805 https://reactome.org/PathwayBrowser/#/R-CFA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Canis familiaris 58443 R-DME-73800 https://reactome.org/PathwayBrowser/#/R-DME-73800 SAICAR => AICAR + Fumarate IEA Drosophila melanogaster 58443 R-DME-73805 https://reactome.org/PathwayBrowser/#/R-DME-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Drosophila melanogaster 58443 R-DRE-73805 https://reactome.org/PathwayBrowser/#/R-DRE-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Danio rerio 58443 R-GGA-419223 https://reactome.org/PathwayBrowser/#/R-GGA-419223 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 58443 R-GGA-419255 https://reactome.org/PathwayBrowser/#/R-GGA-419255 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + fumarate TAS Gallus gallus 58443 R-GGA-73800 https://reactome.org/PathwayBrowser/#/R-GGA-73800 SAICAR => AICAR + Fumarate IEA Gallus gallus 58443 R-GGA-73805 https://reactome.org/PathwayBrowser/#/R-GGA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Gallus gallus 58443 R-HSA-73800 https://reactome.org/PathwayBrowser/#/R-HSA-73800 SAICAR => AICAR + Fumarate TAS Homo sapiens 58443 R-HSA-73805 https://reactome.org/PathwayBrowser/#/R-HSA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi TAS Homo sapiens 58443 R-MMU-73800 https://reactome.org/PathwayBrowser/#/R-MMU-73800 SAICAR => AICAR + Fumarate IEA Mus musculus 58443 R-MMU-73805 https://reactome.org/PathwayBrowser/#/R-MMU-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Mus musculus 58443 R-RNO-73800 https://reactome.org/PathwayBrowser/#/R-RNO-73800 SAICAR => AICAR + Fumarate IEA Rattus norvegicus 58443 R-RNO-73805 https://reactome.org/PathwayBrowser/#/R-RNO-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Rattus norvegicus 58443 R-SCE-73800 https://reactome.org/PathwayBrowser/#/R-SCE-73800 SAICAR => AICAR + Fumarate IEA Saccharomyces cerevisiae 58443 R-SPO-73800 https://reactome.org/PathwayBrowser/#/R-SPO-73800 SAICAR => AICAR + Fumarate IEA Schizosaccharomyces pombe 58443 R-SSC-73800 https://reactome.org/PathwayBrowser/#/R-SSC-73800 SAICAR => AICAR + Fumarate IEA Sus scrofa 58443 R-SSC-73805 https://reactome.org/PathwayBrowser/#/R-SSC-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Sus scrofa 58443 R-XTR-73800 https://reactome.org/PathwayBrowser/#/R-XTR-73800 SAICAR => AICAR + Fumarate IEA Xenopus tropicalis 58443 R-XTR-73805 https://reactome.org/PathwayBrowser/#/R-XTR-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Xenopus tropicalis 58444 R-BTA-6813740 https://reactome.org/PathwayBrowser/#/R-BTA-6813740 GDE1 hydrolyzes GroPIns IEA Bos taurus 58444 R-CEL-6813740 https://reactome.org/PathwayBrowser/#/R-CEL-6813740 GDE1 hydrolyzes GroPIns IEA Caenorhabditis elegans 58444 R-CFA-6813740 https://reactome.org/PathwayBrowser/#/R-CFA-6813740 GDE1 hydrolyzes GroPIns IEA Canis familiaris 58444 R-DME-6813740 https://reactome.org/PathwayBrowser/#/R-DME-6813740 GDE1 hydrolyzes GroPIns IEA Drosophila melanogaster 58444 R-DRE-6813740 https://reactome.org/PathwayBrowser/#/R-DRE-6813740 GDE1 hydrolyzes GroPIns IEA Danio rerio 58444 R-GGA-6813740 https://reactome.org/PathwayBrowser/#/R-GGA-6813740 GDE1 hydrolyzes GroPIns IEA Gallus gallus 58444 R-HSA-6813740 https://reactome.org/PathwayBrowser/#/R-HSA-6813740 GDE1 hydrolyzes GroPIns TAS Homo sapiens 58444 R-MMU-6813740 https://reactome.org/PathwayBrowser/#/R-MMU-6813740 GDE1 hydrolyzes GroPIns IEA Mus musculus 58444 R-RNO-6813740 https://reactome.org/PathwayBrowser/#/R-RNO-6813740 GDE1 hydrolyzes GroPIns IEA Rattus norvegicus 58444 R-SSC-6813740 https://reactome.org/PathwayBrowser/#/R-SSC-6813740 GDE1 hydrolyzes GroPIns IEA Sus scrofa 58444 R-XTR-6813740 https://reactome.org/PathwayBrowser/#/R-XTR-6813740 GDE1 hydrolyzes GroPIns IEA Xenopus tropicalis 58445 R-BTA-8876789 https://reactome.org/PathwayBrowser/#/R-BTA-8876789 CARNMT1 methylates CARN to Anserine IEA Bos taurus 58445 R-CFA-8876789 https://reactome.org/PathwayBrowser/#/R-CFA-8876789 CARNMT1 methylates CARN to Anserine IEA Canis familiaris 58445 R-DDI-8876789 https://reactome.org/PathwayBrowser/#/R-DDI-8876789 CARNMT1 methylates CARN to Anserine IEA Dictyostelium discoideum 58445 R-DME-8876789 https://reactome.org/PathwayBrowser/#/R-DME-8876789 CARNMT1 methylates CARN to Anserine IEA Drosophila melanogaster 58445 R-GGA-8876789 https://reactome.org/PathwayBrowser/#/R-GGA-8876789 CARNMT1 methylates CARN to Anserine IEA Gallus gallus 58445 R-HSA-8876789 https://reactome.org/PathwayBrowser/#/R-HSA-8876789 CARNMT1 methylates CARN to Anserine TAS Homo sapiens 58445 R-MMU-8876789 https://reactome.org/PathwayBrowser/#/R-MMU-8876789 CARNMT1 methylates CARN to Anserine IEA Mus musculus 58445 R-PFA-8876789 https://reactome.org/PathwayBrowser/#/R-PFA-8876789 CARNMT1 methylates CARN to Anserine IEA Plasmodium falciparum 58445 R-RNO-8876789 https://reactome.org/PathwayBrowser/#/R-RNO-8876789 CARNMT1 methylates CARN to Anserine IEA Rattus norvegicus 58445 R-SCE-8876789 https://reactome.org/PathwayBrowser/#/R-SCE-8876789 CARNMT1 methylates CARN to Anserine IEA Saccharomyces cerevisiae 58445 R-SPO-8876789 https://reactome.org/PathwayBrowser/#/R-SPO-8876789 CARNMT1 methylates CARN to Anserine IEA Schizosaccharomyces pombe 58445 R-SSC-8876789 https://reactome.org/PathwayBrowser/#/R-SSC-8876789 CARNMT1 methylates CARN to Anserine IEA Sus scrofa 58450 R-BTA-6810472 https://reactome.org/PathwayBrowser/#/R-BTA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Bos taurus 58450 R-CFA-6810472 https://reactome.org/PathwayBrowser/#/R-CFA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Canis familiaris 58450 R-GGA-6810472 https://reactome.org/PathwayBrowser/#/R-GGA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Gallus gallus 58450 R-HSA-6810472 https://reactome.org/PathwayBrowser/#/R-HSA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP TAS Homo sapiens 58450 R-MMU-6810472 https://reactome.org/PathwayBrowser/#/R-MMU-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Mus musculus 58450 R-RNO-6810472 https://reactome.org/PathwayBrowser/#/R-RNO-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Rattus norvegicus 58450 R-SSC-6810472 https://reactome.org/PathwayBrowser/#/R-SSC-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Sus scrofa 58450 R-XTR-6810472 https://reactome.org/PathwayBrowser/#/R-XTR-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Xenopus tropicalis 58456 R-BTA-109699 https://reactome.org/PathwayBrowser/#/R-BTA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-1112666 https://reactome.org/PathwayBrowser/#/R-BTA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Bos taurus 58456 R-BTA-111879 https://reactome.org/PathwayBrowser/#/R-BTA-111879 PIP2 hydrolysis IEA Bos taurus 58456 R-BTA-114688 https://reactome.org/PathwayBrowser/#/R-BTA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Bos taurus 58456 R-BTA-114689 https://reactome.org/PathwayBrowser/#/R-BTA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Bos taurus 58456 R-BTA-1250370 https://reactome.org/PathwayBrowser/#/R-BTA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Bos taurus 58456 R-BTA-1250462 https://reactome.org/PathwayBrowser/#/R-BTA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Bos taurus 58456 R-BTA-1306957 https://reactome.org/PathwayBrowser/#/R-BTA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Bos taurus 58456 R-BTA-1306979 https://reactome.org/PathwayBrowser/#/R-BTA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Bos taurus 58456 R-BTA-1433514 https://reactome.org/PathwayBrowser/#/R-BTA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Bos taurus 58456 R-BTA-1675776 https://reactome.org/PathwayBrowser/#/R-BTA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Bos taurus 58456 R-BTA-1675824 https://reactome.org/PathwayBrowser/#/R-BTA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Bos taurus 58456 R-BTA-1676048 https://reactome.org/PathwayBrowser/#/R-BTA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Bos taurus 58456 R-BTA-1676082 https://reactome.org/PathwayBrowser/#/R-BTA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Bos taurus 58456 R-BTA-1676177 https://reactome.org/PathwayBrowser/#/R-BTA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Bos taurus 58456 R-BTA-177939 https://reactome.org/PathwayBrowser/#/R-BTA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Bos taurus 58456 R-BTA-1855177 https://reactome.org/PathwayBrowser/#/R-BTA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Bos taurus 58456 R-BTA-1855214 https://reactome.org/PathwayBrowser/#/R-BTA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Bos taurus 58456 R-BTA-1855221 https://reactome.org/PathwayBrowser/#/R-BTA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Bos taurus 58456 R-BTA-186800 https://reactome.org/PathwayBrowser/#/R-BTA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-198266 https://reactome.org/PathwayBrowser/#/R-BTA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Bos taurus 58456 R-BTA-199456 https://reactome.org/PathwayBrowser/#/R-BTA-199456 PTEN dephosphorylates PIP3 IEA Bos taurus 58456 R-BTA-201510 https://reactome.org/PathwayBrowser/#/R-BTA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Bos taurus 58456 R-BTA-202354 https://reactome.org/PathwayBrowser/#/R-BTA-202354 Translocation of PLC-gamma1 to PIP2 IEA Bos taurus 58456 R-BTA-202365 https://reactome.org/PathwayBrowser/#/R-BTA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-202407 https://reactome.org/PathwayBrowser/#/R-BTA-202407 PLC-gamma1 hydrolyses PIP2 IEA Bos taurus 58456 R-BTA-2029271 https://reactome.org/PathwayBrowser/#/R-BTA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-2029466 https://reactome.org/PathwayBrowser/#/R-BTA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Bos taurus 58456 R-BTA-2045911 https://reactome.org/PathwayBrowser/#/R-BTA-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Bos taurus 58456 R-BTA-2076220 https://reactome.org/PathwayBrowser/#/R-BTA-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Bos taurus 58456 R-BTA-2197690 https://reactome.org/PathwayBrowser/#/R-BTA-2197690 Detachment of WASP/WAVE IEA Bos taurus 58456 R-BTA-2197698 https://reactome.org/PathwayBrowser/#/R-BTA-2197698 Src phosphorylate WASP,N-WASP IEA Bos taurus 58456 R-BTA-2219524 https://reactome.org/PathwayBrowser/#/R-BTA-2219524 PDPK1 binds PIP2 IEA Bos taurus 58456 R-BTA-2316434 https://reactome.org/PathwayBrowser/#/R-BTA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-2424480 https://reactome.org/PathwayBrowser/#/R-BTA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-2559456 https://reactome.org/PathwayBrowser/#/R-BTA-2559456 TIRAP binds PIP2-rich regions in the plasma membrane IEA Bos taurus 58456 R-BTA-2730847 https://reactome.org/PathwayBrowser/#/R-BTA-2730847 Hydrolysis of PIP2 by PLCG IEA Bos taurus 58456 R-BTA-2730870 https://reactome.org/PathwayBrowser/#/R-BTA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Bos taurus 58456 R-BTA-354060 https://reactome.org/PathwayBrowser/#/R-BTA-354060 Translocation of RIAM to plasma membrane IEA Bos taurus 58456 R-BTA-354066 https://reactome.org/PathwayBrowser/#/R-BTA-354066 Translocation of PTK2 to Focal complexes IEA Bos taurus 58456 R-BTA-354073 https://reactome.org/PathwayBrowser/#/R-BTA-354073 Autophosphorylation of PTK2 at Y397 IEA Bos taurus 58456 R-BTA-354077 https://reactome.org/PathwayBrowser/#/R-BTA-354077 Integrin alphaIIb beta3 activation IEA Bos taurus 58456 R-BTA-354087 https://reactome.org/PathwayBrowser/#/R-BTA-354087 Recruitment of GRB2 to p-PTK2 IEA Bos taurus 58456 R-BTA-354097 https://reactome.org/PathwayBrowser/#/R-BTA-354097 Activation of Talin IEA Bos taurus 58456 R-BTA-354124 https://reactome.org/PathwayBrowser/#/R-BTA-354124 Phosphorylation of pPTK2 by SRC IEA Bos taurus 58456 R-BTA-354149 https://reactome.org/PathwayBrowser/#/R-BTA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Bos taurus 58456 R-BTA-354165 https://reactome.org/PathwayBrowser/#/R-BTA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Bos taurus 58456 R-BTA-372693 https://reactome.org/PathwayBrowser/#/R-BTA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Bos taurus 58456 R-BTA-372697 https://reactome.org/PathwayBrowser/#/R-BTA-372697 Crk binding to p130cas IEA Bos taurus 58456 R-BTA-372705 https://reactome.org/PathwayBrowser/#/R-BTA-372705 Recruitment of BCAR1 to PTK2 complex IEA Bos taurus 58456 R-BTA-374662 https://reactome.org/PathwayBrowser/#/R-BTA-374662 Translocation of Ezrin to plasma membrane IEA Bos taurus 58456 R-BTA-374663 https://reactome.org/PathwayBrowser/#/R-BTA-374663 DCC interaction with Ezrin IEA Bos taurus 58456 R-BTA-374664 https://reactome.org/PathwayBrowser/#/R-BTA-374664 Phosphorylation and activation of Ezrin IEA Bos taurus 58456 R-BTA-3772436 https://reactome.org/PathwayBrowser/#/R-BTA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Bos taurus 58456 R-BTA-377640 https://reactome.org/PathwayBrowser/#/R-BTA-377640 Autophosphorylation of SRC IEA Bos taurus 58456 R-BTA-377641 https://reactome.org/PathwayBrowser/#/R-BTA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Bos taurus 58456 R-BTA-377643 https://reactome.org/PathwayBrowser/#/R-BTA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Bos taurus 58456 R-BTA-377644 https://reactome.org/PathwayBrowser/#/R-BTA-377644 Release of CSK from SRC IEA Bos taurus 58456 R-BTA-389158 https://reactome.org/PathwayBrowser/#/R-BTA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-392300 https://reactome.org/PathwayBrowser/#/R-BTA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-3928595 https://reactome.org/PathwayBrowser/#/R-BTA-3928595 N-WASP binds ARP2/3 and G-actin IEA Bos taurus 58456 R-BTA-3928601 https://reactome.org/PathwayBrowser/#/R-BTA-3928601 CDC42 and PIP2 bind WASL, activating it IEA Bos taurus 58456 R-BTA-398193 https://reactome.org/PathwayBrowser/#/R-BTA-398193 PLC beta-mediated PIP2 hydrolysis IEA Bos taurus 58456 R-BTA-399998 https://reactome.org/PathwayBrowser/#/R-BTA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Bos taurus 58456 R-BTA-418874 https://reactome.org/PathwayBrowser/#/R-BTA-418874 Recruitment and activation of N-WASP by Cdc42 IEA Bos taurus 58456 R-BTA-429415 https://reactome.org/PathwayBrowser/#/R-BTA-429415 SYK binds to integrin alphaIIb beta3 IEA Bos taurus 58456 R-BTA-429441 https://reactome.org/PathwayBrowser/#/R-BTA-429441 SYK activation by SRC IEA Bos taurus 58456 R-BTA-432096 https://reactome.org/PathwayBrowser/#/R-BTA-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Bos taurus 58456 R-BTA-437162 https://reactome.org/PathwayBrowser/#/R-BTA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-442273 https://reactome.org/PathwayBrowser/#/R-BTA-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Bos taurus 58456 R-BTA-443905 https://reactome.org/PathwayBrowser/#/R-BTA-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Bos taurus 58456 R-BTA-443910 https://reactome.org/PathwayBrowser/#/R-BTA-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Bos taurus 58456 R-BTA-449058 https://reactome.org/PathwayBrowser/#/R-BTA-449058 Interleukin-1 family are secreted IEA Bos taurus 58456 R-BTA-5218819 https://reactome.org/PathwayBrowser/#/R-BTA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-5607735 https://reactome.org/PathwayBrowser/#/R-BTA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Bos taurus 58456 R-BTA-5620975 https://reactome.org/PathwayBrowser/#/R-BTA-5620975 MLKL binds PIPs IEA Bos taurus 58456 R-BTA-5654690 https://reactome.org/PathwayBrowser/#/R-BTA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-5654692 https://reactome.org/PathwayBrowser/#/R-BTA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-5654697 https://reactome.org/PathwayBrowser/#/R-BTA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-5654701 https://reactome.org/PathwayBrowser/#/R-BTA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-5654705 https://reactome.org/PathwayBrowser/#/R-BTA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-5654709 https://reactome.org/PathwayBrowser/#/R-BTA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-5654714 https://reactome.org/PathwayBrowser/#/R-BTA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-5654717 https://reactome.org/PathwayBrowser/#/R-BTA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-5672972 https://reactome.org/PathwayBrowser/#/R-BTA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Bos taurus 58456 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 58456 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 58456 R-BTA-5672980 https://reactome.org/PathwayBrowser/#/R-BTA-5672980 Dissociation of RAS:RAF complex IEA Bos taurus 58456 R-BTA-6805981 https://reactome.org/PathwayBrowser/#/R-BTA-6805981 HMGB1 release from cells IEA Bos taurus 58456 R-BTA-6810410 https://reactome.org/PathwayBrowser/#/R-BTA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Bos taurus 58456 R-BTA-6811522 https://reactome.org/PathwayBrowser/#/R-BTA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Bos taurus 58456 R-BTA-8849969 https://reactome.org/PathwayBrowser/#/R-BTA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Bos taurus 58456 R-BTA-8852019 https://reactome.org/PathwayBrowser/#/R-BTA-8852019 MET bound PI3K generates PIP3 IEA Bos taurus 58456 R-BTA-8856808 https://reactome.org/PathwayBrowser/#/R-BTA-8856808 Recruitment of AP-2 complex and clathrin IEA Bos taurus 58456 R-BTA-8856813 https://reactome.org/PathwayBrowser/#/R-BTA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Bos taurus 58456 R-BTA-8866283 https://reactome.org/PathwayBrowser/#/R-BTA-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Bos taurus 58456 R-BTA-8867041 https://reactome.org/PathwayBrowser/#/R-BTA-8867041 EGFR phosphorylates EPS15 IEA Bos taurus 58456 R-BTA-8867044 https://reactome.org/PathwayBrowser/#/R-BTA-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Bos taurus 58456 R-BTA-8867047 https://reactome.org/PathwayBrowser/#/R-BTA-8867047 PTPN3 dephosphorylates EPS15 IEA Bos taurus 58456 R-BTA-8867754 https://reactome.org/PathwayBrowser/#/R-BTA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Bos taurus 58456 R-BTA-8867756 https://reactome.org/PathwayBrowser/#/R-BTA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Bos taurus 58456 R-BTA-8868066 https://reactome.org/PathwayBrowser/#/R-BTA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Bos taurus 58456 R-BTA-8868071 https://reactome.org/PathwayBrowser/#/R-BTA-8868071 Clathrin recruits PIK3C2A IEA Bos taurus 58456 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 58456 R-BTA-8868230 https://reactome.org/PathwayBrowser/#/R-BTA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Bos taurus 58456 R-BTA-8868236 https://reactome.org/PathwayBrowser/#/R-BTA-8868236 BAR domain proteins recruit dynamin IEA Bos taurus 58456 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 58456 R-BTA-8868651 https://reactome.org/PathwayBrowser/#/R-BTA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Bos taurus 58456 R-BTA-8871196 https://reactome.org/PathwayBrowser/#/R-BTA-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Bos taurus 58456 R-BTA-8874470 https://reactome.org/PathwayBrowser/#/R-BTA-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Bos taurus 58456 R-BTA-9021627 https://reactome.org/PathwayBrowser/#/R-BTA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus 58456 R-BTA-9647619 https://reactome.org/PathwayBrowser/#/R-BTA-9647619 GSDMD forms ring‐shaped oligomers IEA Bos taurus 58456 R-BTA-9647631 https://reactome.org/PathwayBrowser/#/R-BTA-9647631 GSDMD (1-275) binds PIPs IEA Bos taurus 58456 R-BTA-9647645 https://reactome.org/PathwayBrowser/#/R-BTA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Bos taurus 58456 R-BTA-9647660 https://reactome.org/PathwayBrowser/#/R-BTA-9647660 GSDME (1-270) binds PIPs IEA Bos taurus 58456 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus 58456 R-BTA-9657603 https://reactome.org/PathwayBrowser/#/R-BTA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Bos taurus 58456 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 58456 R-BTA-9657608 https://reactome.org/PathwayBrowser/#/R-BTA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Bos taurus 58456 R-BTA-9710254 https://reactome.org/PathwayBrowser/#/R-BTA-9710254 GSDME oligomerizes IEA Bos taurus 58456 R-CEL-111879 https://reactome.org/PathwayBrowser/#/R-CEL-111879 PIP2 hydrolysis IEA Caenorhabditis elegans 58456 R-CEL-114688 https://reactome.org/PathwayBrowser/#/R-CEL-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Caenorhabditis elegans 58456 R-CEL-1250370 https://reactome.org/PathwayBrowser/#/R-CEL-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Caenorhabditis elegans 58456 R-CEL-1250462 https://reactome.org/PathwayBrowser/#/R-CEL-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Caenorhabditis elegans 58456 R-CEL-1306957 https://reactome.org/PathwayBrowser/#/R-CEL-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Caenorhabditis elegans 58456 R-CEL-1306979 https://reactome.org/PathwayBrowser/#/R-CEL-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Caenorhabditis elegans 58456 R-CEL-1433514 https://reactome.org/PathwayBrowser/#/R-CEL-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Caenorhabditis elegans 58456 R-CEL-1675776 https://reactome.org/PathwayBrowser/#/R-CEL-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Caenorhabditis elegans 58456 R-CEL-1675824 https://reactome.org/PathwayBrowser/#/R-CEL-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Caenorhabditis elegans 58456 R-CEL-1676048 https://reactome.org/PathwayBrowser/#/R-CEL-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Caenorhabditis elegans 58456 R-CEL-1676082 https://reactome.org/PathwayBrowser/#/R-CEL-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Caenorhabditis elegans 58456 R-CEL-1676177 https://reactome.org/PathwayBrowser/#/R-CEL-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Caenorhabditis elegans 58456 R-CEL-177939 https://reactome.org/PathwayBrowser/#/R-CEL-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Caenorhabditis elegans 58456 R-CEL-1855177 https://reactome.org/PathwayBrowser/#/R-CEL-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Caenorhabditis elegans 58456 R-CEL-1855214 https://reactome.org/PathwayBrowser/#/R-CEL-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Caenorhabditis elegans 58456 R-CEL-1855221 https://reactome.org/PathwayBrowser/#/R-CEL-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Caenorhabditis elegans 58456 R-CEL-186800 https://reactome.org/PathwayBrowser/#/R-CEL-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Caenorhabditis elegans 58456 R-CEL-199456 https://reactome.org/PathwayBrowser/#/R-CEL-199456 PTEN dephosphorylates PIP3 IEA Caenorhabditis elegans 58456 R-CEL-201510 https://reactome.org/PathwayBrowser/#/R-CEL-201510 PI3K synthesizes PIP3 downstream of ALK IEA Caenorhabditis elegans 58456 R-CEL-2029466 https://reactome.org/PathwayBrowser/#/R-CEL-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Caenorhabditis elegans 58456 R-CEL-2197690 https://reactome.org/PathwayBrowser/#/R-CEL-2197690 Detachment of WASP/WAVE IEA Caenorhabditis elegans 58456 R-CEL-2197698 https://reactome.org/PathwayBrowser/#/R-CEL-2197698 Src phosphorylate WASP,N-WASP IEA Caenorhabditis elegans 58456 R-CEL-2219524 https://reactome.org/PathwayBrowser/#/R-CEL-2219524 PDPK1 binds PIP2 IEA Caenorhabditis elegans 58456 R-CEL-2316434 https://reactome.org/PathwayBrowser/#/R-CEL-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 58456 R-CEL-2750187 https://reactome.org/PathwayBrowser/#/R-CEL-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Caenorhabditis elegans 58456 R-CEL-354060 https://reactome.org/PathwayBrowser/#/R-CEL-354060 Translocation of RIAM to plasma membrane IEA Caenorhabditis elegans 58456 R-CEL-354066 https://reactome.org/PathwayBrowser/#/R-CEL-354066 Translocation of PTK2 to Focal complexes IEA Caenorhabditis elegans 58456 R-CEL-354073 https://reactome.org/PathwayBrowser/#/R-CEL-354073 Autophosphorylation of PTK2 at Y397 IEA Caenorhabditis elegans 58456 R-CEL-354077 https://reactome.org/PathwayBrowser/#/R-CEL-354077 Integrin alphaIIb beta3 activation IEA Caenorhabditis elegans 58456 R-CEL-354087 https://reactome.org/PathwayBrowser/#/R-CEL-354087 Recruitment of GRB2 to p-PTK2 IEA Caenorhabditis elegans 58456 R-CEL-354097 https://reactome.org/PathwayBrowser/#/R-CEL-354097 Activation of Talin IEA Caenorhabditis elegans 58456 R-CEL-354124 https://reactome.org/PathwayBrowser/#/R-CEL-354124 Phosphorylation of pPTK2 by SRC IEA Caenorhabditis elegans 58456 R-CEL-354149 https://reactome.org/PathwayBrowser/#/R-CEL-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Caenorhabditis elegans 58456 R-CEL-354165 https://reactome.org/PathwayBrowser/#/R-CEL-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Caenorhabditis elegans 58456 R-CEL-374662 https://reactome.org/PathwayBrowser/#/R-CEL-374662 Translocation of Ezrin to plasma membrane IEA Caenorhabditis elegans 58456 R-CEL-374663 https://reactome.org/PathwayBrowser/#/R-CEL-374663 DCC interaction with Ezrin IEA Caenorhabditis elegans 58456 R-CEL-374664 https://reactome.org/PathwayBrowser/#/R-CEL-374664 Phosphorylation and activation of Ezrin IEA Caenorhabditis elegans 58456 R-CEL-374680 https://reactome.org/PathwayBrowser/#/R-CEL-374680 L1 trans-homophilic interaction IEA Caenorhabditis elegans 58456 R-CEL-3772436 https://reactome.org/PathwayBrowser/#/R-CEL-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Caenorhabditis elegans 58456 R-CEL-377640 https://reactome.org/PathwayBrowser/#/R-CEL-377640 Autophosphorylation of SRC IEA Caenorhabditis elegans 58456 R-CEL-377641 https://reactome.org/PathwayBrowser/#/R-CEL-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Caenorhabditis elegans 58456 R-CEL-377644 https://reactome.org/PathwayBrowser/#/R-CEL-377644 Release of CSK from SRC IEA Caenorhabditis elegans 58456 R-CEL-3928595 https://reactome.org/PathwayBrowser/#/R-CEL-3928595 N-WASP binds ARP2/3 and G-actin IEA Caenorhabditis elegans 58456 R-CEL-3928601 https://reactome.org/PathwayBrowser/#/R-CEL-3928601 CDC42 and PIP2 bind WASL, activating it IEA Caenorhabditis elegans 58456 R-CEL-429415 https://reactome.org/PathwayBrowser/#/R-CEL-429415 SYK binds to integrin alphaIIb beta3 IEA Caenorhabditis elegans 58456 R-CEL-429441 https://reactome.org/PathwayBrowser/#/R-CEL-429441 SYK activation by SRC IEA Caenorhabditis elegans 58456 R-CEL-437162 https://reactome.org/PathwayBrowser/#/R-CEL-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Caenorhabditis elegans 58456 R-CEL-442273 https://reactome.org/PathwayBrowser/#/R-CEL-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Caenorhabditis elegans 58456 R-CEL-443779 https://reactome.org/PathwayBrowser/#/R-CEL-443779 Linkage of L1 with treadmilling F-actin IEA Caenorhabditis elegans 58456 R-CEL-443905 https://reactome.org/PathwayBrowser/#/R-CEL-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Caenorhabditis elegans 58456 R-CEL-5218819 https://reactome.org/PathwayBrowser/#/R-CEL-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 58456 R-CEL-5654690 https://reactome.org/PathwayBrowser/#/R-CEL-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 58456 R-CEL-5654717 https://reactome.org/PathwayBrowser/#/R-CEL-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans 58456 R-CEL-5672972 https://reactome.org/PathwayBrowser/#/R-CEL-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Caenorhabditis elegans 58456 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 58456 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 58456 R-CEL-5672980 https://reactome.org/PathwayBrowser/#/R-CEL-5672980 Dissociation of RAS:RAF complex IEA Caenorhabditis elegans 58456 R-CEL-6810410 https://reactome.org/PathwayBrowser/#/R-CEL-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Caenorhabditis elegans 58456 R-CEL-6811522 https://reactome.org/PathwayBrowser/#/R-CEL-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Caenorhabditis elegans 58456 R-CEL-8849969 https://reactome.org/PathwayBrowser/#/R-CEL-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Caenorhabditis elegans 58456 R-CEL-8852019 https://reactome.org/PathwayBrowser/#/R-CEL-8852019 MET bound PI3K generates PIP3 IEA Caenorhabditis elegans 58456 R-CEL-8856813 https://reactome.org/PathwayBrowser/#/R-CEL-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Caenorhabditis elegans 58456 R-CEL-8866283 https://reactome.org/PathwayBrowser/#/R-CEL-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Caenorhabditis elegans 58456 R-CEL-8867041 https://reactome.org/PathwayBrowser/#/R-CEL-8867041 EGFR phosphorylates EPS15 IEA Caenorhabditis elegans 58456 R-CEL-8867044 https://reactome.org/PathwayBrowser/#/R-CEL-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Caenorhabditis elegans 58456 R-CEL-8867047 https://reactome.org/PathwayBrowser/#/R-CEL-8867047 PTPN3 dephosphorylates EPS15 IEA Caenorhabditis elegans 58456 R-CEL-8867756 https://reactome.org/PathwayBrowser/#/R-CEL-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Caenorhabditis elegans 58456 R-CEL-8868066 https://reactome.org/PathwayBrowser/#/R-CEL-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Caenorhabditis elegans 58456 R-CEL-8868072 https://reactome.org/PathwayBrowser/#/R-CEL-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Caenorhabditis elegans 58456 R-CEL-8868236 https://reactome.org/PathwayBrowser/#/R-CEL-8868236 BAR domain proteins recruit dynamin IEA Caenorhabditis elegans 58456 R-CEL-8868648 https://reactome.org/PathwayBrowser/#/R-CEL-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Caenorhabditis elegans 58456 R-CEL-8868651 https://reactome.org/PathwayBrowser/#/R-CEL-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Caenorhabditis elegans 58456 R-CEL-8871196 https://reactome.org/PathwayBrowser/#/R-CEL-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Caenorhabditis elegans 58456 R-CEL-9657599 https://reactome.org/PathwayBrowser/#/R-CEL-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Caenorhabditis elegans 58456 R-CEL-9657603 https://reactome.org/PathwayBrowser/#/R-CEL-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Caenorhabditis elegans 58456 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 58456 R-CEL-9657608 https://reactome.org/PathwayBrowser/#/R-CEL-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Caenorhabditis elegans 58456 R-CFA-109699 https://reactome.org/PathwayBrowser/#/R-CFA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-1112666 https://reactome.org/PathwayBrowser/#/R-CFA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Canis familiaris 58456 R-CFA-111879 https://reactome.org/PathwayBrowser/#/R-CFA-111879 PIP2 hydrolysis IEA Canis familiaris 58456 R-CFA-114688 https://reactome.org/PathwayBrowser/#/R-CFA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Canis familiaris 58456 R-CFA-114689 https://reactome.org/PathwayBrowser/#/R-CFA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Canis familiaris 58456 R-CFA-1250370 https://reactome.org/PathwayBrowser/#/R-CFA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Canis familiaris 58456 R-CFA-1250462 https://reactome.org/PathwayBrowser/#/R-CFA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Canis familiaris 58456 R-CFA-1306957 https://reactome.org/PathwayBrowser/#/R-CFA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Canis familiaris 58456 R-CFA-1306979 https://reactome.org/PathwayBrowser/#/R-CFA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Canis familiaris 58456 R-CFA-1433514 https://reactome.org/PathwayBrowser/#/R-CFA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Canis familiaris 58456 R-CFA-1675776 https://reactome.org/PathwayBrowser/#/R-CFA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Canis familiaris 58456 R-CFA-1675824 https://reactome.org/PathwayBrowser/#/R-CFA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Canis familiaris 58456 R-CFA-1676048 https://reactome.org/PathwayBrowser/#/R-CFA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Canis familiaris 58456 R-CFA-1676082 https://reactome.org/PathwayBrowser/#/R-CFA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Canis familiaris 58456 R-CFA-1676177 https://reactome.org/PathwayBrowser/#/R-CFA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Canis familiaris 58456 R-CFA-177939 https://reactome.org/PathwayBrowser/#/R-CFA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Canis familiaris 58456 R-CFA-1855177 https://reactome.org/PathwayBrowser/#/R-CFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Canis familiaris 58456 R-CFA-1855214 https://reactome.org/PathwayBrowser/#/R-CFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Canis familiaris 58456 R-CFA-1855221 https://reactome.org/PathwayBrowser/#/R-CFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Canis familiaris 58456 R-CFA-186800 https://reactome.org/PathwayBrowser/#/R-CFA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-198266 https://reactome.org/PathwayBrowser/#/R-CFA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Canis familiaris 58456 R-CFA-199456 https://reactome.org/PathwayBrowser/#/R-CFA-199456 PTEN dephosphorylates PIP3 IEA Canis familiaris 58456 R-CFA-201510 https://reactome.org/PathwayBrowser/#/R-CFA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Canis familiaris 58456 R-CFA-202354 https://reactome.org/PathwayBrowser/#/R-CFA-202354 Translocation of PLC-gamma1 to PIP2 IEA Canis familiaris 58456 R-CFA-202365 https://reactome.org/PathwayBrowser/#/R-CFA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-202407 https://reactome.org/PathwayBrowser/#/R-CFA-202407 PLC-gamma1 hydrolyses PIP2 IEA Canis familiaris 58456 R-CFA-2029271 https://reactome.org/PathwayBrowser/#/R-CFA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-2029466 https://reactome.org/PathwayBrowser/#/R-CFA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Canis familiaris 58456 R-CFA-2045911 https://reactome.org/PathwayBrowser/#/R-CFA-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Canis familiaris 58456 R-CFA-2076220 https://reactome.org/PathwayBrowser/#/R-CFA-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Canis familiaris 58456 R-CFA-2197690 https://reactome.org/PathwayBrowser/#/R-CFA-2197690 Detachment of WASP/WAVE IEA Canis familiaris 58456 R-CFA-2197691 https://reactome.org/PathwayBrowser/#/R-CFA-2197691 WIP binds WASP,N-WASP, activating them IEA Canis familiaris 58456 R-CFA-2197698 https://reactome.org/PathwayBrowser/#/R-CFA-2197698 Src phosphorylate WASP,N-WASP IEA Canis familiaris 58456 R-CFA-2219524 https://reactome.org/PathwayBrowser/#/R-CFA-2219524 PDPK1 binds PIP2 IEA Canis familiaris 58456 R-CFA-2316434 https://reactome.org/PathwayBrowser/#/R-CFA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-2424480 https://reactome.org/PathwayBrowser/#/R-CFA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-2559456 https://reactome.org/PathwayBrowser/#/R-CFA-2559456 TIRAP binds PIP2-rich regions in the plasma membrane IEA Canis familiaris 58456 R-CFA-2730847 https://reactome.org/PathwayBrowser/#/R-CFA-2730847 Hydrolysis of PIP2 by PLCG IEA Canis familiaris 58456 R-CFA-2730870 https://reactome.org/PathwayBrowser/#/R-CFA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Canis familiaris 58456 R-CFA-2750187 https://reactome.org/PathwayBrowser/#/R-CFA-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Canis familiaris 58456 R-CFA-354060 https://reactome.org/PathwayBrowser/#/R-CFA-354060 Translocation of RIAM to plasma membrane IEA Canis familiaris 58456 R-CFA-354066 https://reactome.org/PathwayBrowser/#/R-CFA-354066 Translocation of PTK2 to Focal complexes IEA Canis familiaris 58456 R-CFA-354073 https://reactome.org/PathwayBrowser/#/R-CFA-354073 Autophosphorylation of PTK2 at Y397 IEA Canis familiaris 58456 R-CFA-354077 https://reactome.org/PathwayBrowser/#/R-CFA-354077 Integrin alphaIIb beta3 activation IEA Canis familiaris 58456 R-CFA-354087 https://reactome.org/PathwayBrowser/#/R-CFA-354087 Recruitment of GRB2 to p-PTK2 IEA Canis familiaris 58456 R-CFA-354097 https://reactome.org/PathwayBrowser/#/R-CFA-354097 Activation of Talin IEA Canis familiaris 58456 R-CFA-354124 https://reactome.org/PathwayBrowser/#/R-CFA-354124 Phosphorylation of pPTK2 by SRC IEA Canis familiaris 58456 R-CFA-354149 https://reactome.org/PathwayBrowser/#/R-CFA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Canis familiaris 58456 R-CFA-354165 https://reactome.org/PathwayBrowser/#/R-CFA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Canis familiaris 58456 R-CFA-372693 https://reactome.org/PathwayBrowser/#/R-CFA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Canis familiaris 58456 R-CFA-372697 https://reactome.org/PathwayBrowser/#/R-CFA-372697 Crk binding to p130cas IEA Canis familiaris 58456 R-CFA-372705 https://reactome.org/PathwayBrowser/#/R-CFA-372705 Recruitment of BCAR1 to PTK2 complex IEA Canis familiaris 58456 R-CFA-374662 https://reactome.org/PathwayBrowser/#/R-CFA-374662 Translocation of Ezrin to plasma membrane IEA Canis familiaris 58456 R-CFA-374663 https://reactome.org/PathwayBrowser/#/R-CFA-374663 DCC interaction with Ezrin IEA Canis familiaris 58456 R-CFA-374664 https://reactome.org/PathwayBrowser/#/R-CFA-374664 Phosphorylation and activation of Ezrin IEA Canis familiaris 58456 R-CFA-3772436 https://reactome.org/PathwayBrowser/#/R-CFA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Canis familiaris 58456 R-CFA-377640 https://reactome.org/PathwayBrowser/#/R-CFA-377640 Autophosphorylation of SRC IEA Canis familiaris 58456 R-CFA-377641 https://reactome.org/PathwayBrowser/#/R-CFA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Canis familiaris 58456 R-CFA-377643 https://reactome.org/PathwayBrowser/#/R-CFA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Canis familiaris 58456 R-CFA-377644 https://reactome.org/PathwayBrowser/#/R-CFA-377644 Release of CSK from SRC IEA Canis familiaris 58456 R-CFA-389158 https://reactome.org/PathwayBrowser/#/R-CFA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-392300 https://reactome.org/PathwayBrowser/#/R-CFA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-3928595 https://reactome.org/PathwayBrowser/#/R-CFA-3928595 N-WASP binds ARP2/3 and G-actin IEA Canis familiaris 58456 R-CFA-3928601 https://reactome.org/PathwayBrowser/#/R-CFA-3928601 CDC42 and PIP2 bind WASL, activating it IEA Canis familiaris 58456 R-CFA-398193 https://reactome.org/PathwayBrowser/#/R-CFA-398193 PLC beta-mediated PIP2 hydrolysis IEA Canis familiaris 58456 R-CFA-399998 https://reactome.org/PathwayBrowser/#/R-CFA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Canis familiaris 58456 R-CFA-418874 https://reactome.org/PathwayBrowser/#/R-CFA-418874 Recruitment and activation of N-WASP by Cdc42 IEA Canis familiaris 58456 R-CFA-429415 https://reactome.org/PathwayBrowser/#/R-CFA-429415 SYK binds to integrin alphaIIb beta3 IEA Canis familiaris 58456 R-CFA-429441 https://reactome.org/PathwayBrowser/#/R-CFA-429441 SYK activation by SRC IEA Canis familiaris 58456 R-CFA-432096 https://reactome.org/PathwayBrowser/#/R-CFA-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Canis familiaris 58456 R-CFA-437162 https://reactome.org/PathwayBrowser/#/R-CFA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-442273 https://reactome.org/PathwayBrowser/#/R-CFA-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Canis familiaris 58456 R-CFA-443905 https://reactome.org/PathwayBrowser/#/R-CFA-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Canis familiaris 58456 R-CFA-443910 https://reactome.org/PathwayBrowser/#/R-CFA-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Canis familiaris 58456 R-CFA-449058 https://reactome.org/PathwayBrowser/#/R-CFA-449058 Interleukin-1 family are secreted IEA Canis familiaris 58456 R-CFA-5218819 https://reactome.org/PathwayBrowser/#/R-CFA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-5607735 https://reactome.org/PathwayBrowser/#/R-CFA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Canis familiaris 58456 R-CFA-5654690 https://reactome.org/PathwayBrowser/#/R-CFA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-5654692 https://reactome.org/PathwayBrowser/#/R-CFA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-5654697 https://reactome.org/PathwayBrowser/#/R-CFA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-5654701 https://reactome.org/PathwayBrowser/#/R-CFA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-5654705 https://reactome.org/PathwayBrowser/#/R-CFA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-5654709 https://reactome.org/PathwayBrowser/#/R-CFA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-5654714 https://reactome.org/PathwayBrowser/#/R-CFA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-5654717 https://reactome.org/PathwayBrowser/#/R-CFA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-5672972 https://reactome.org/PathwayBrowser/#/R-CFA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Canis familiaris 58456 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 58456 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 58456 R-CFA-5672980 https://reactome.org/PathwayBrowser/#/R-CFA-5672980 Dissociation of RAS:RAF complex IEA Canis familiaris 58456 R-CFA-6805981 https://reactome.org/PathwayBrowser/#/R-CFA-6805981 HMGB1 release from cells IEA Canis familiaris 58456 R-CFA-6810410 https://reactome.org/PathwayBrowser/#/R-CFA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Canis familiaris 58456 R-CFA-6811522 https://reactome.org/PathwayBrowser/#/R-CFA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Canis familiaris 58456 R-CFA-8849969 https://reactome.org/PathwayBrowser/#/R-CFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Canis familiaris 58456 R-CFA-8852019 https://reactome.org/PathwayBrowser/#/R-CFA-8852019 MET bound PI3K generates PIP3 IEA Canis familiaris 58456 R-CFA-8856808 https://reactome.org/PathwayBrowser/#/R-CFA-8856808 Recruitment of AP-2 complex and clathrin IEA Canis familiaris 58456 R-CFA-8856813 https://reactome.org/PathwayBrowser/#/R-CFA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Canis familiaris 58456 R-CFA-8866283 https://reactome.org/PathwayBrowser/#/R-CFA-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Canis familiaris 58456 R-CFA-8867041 https://reactome.org/PathwayBrowser/#/R-CFA-8867041 EGFR phosphorylates EPS15 IEA Canis familiaris 58456 R-CFA-8867044 https://reactome.org/PathwayBrowser/#/R-CFA-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Canis familiaris 58456 R-CFA-8867047 https://reactome.org/PathwayBrowser/#/R-CFA-8867047 PTPN3 dephosphorylates EPS15 IEA Canis familiaris 58456 R-CFA-8867754 https://reactome.org/PathwayBrowser/#/R-CFA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Canis familiaris 58456 R-CFA-8867756 https://reactome.org/PathwayBrowser/#/R-CFA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Canis familiaris 58456 R-CFA-8868066 https://reactome.org/PathwayBrowser/#/R-CFA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Canis familiaris 58456 R-CFA-8868071 https://reactome.org/PathwayBrowser/#/R-CFA-8868071 Clathrin recruits PIK3C2A IEA Canis familiaris 58456 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 58456 R-CFA-8868230 https://reactome.org/PathwayBrowser/#/R-CFA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Canis familiaris 58456 R-CFA-8868236 https://reactome.org/PathwayBrowser/#/R-CFA-8868236 BAR domain proteins recruit dynamin IEA Canis familiaris 58456 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 58456 R-CFA-8868651 https://reactome.org/PathwayBrowser/#/R-CFA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Canis familiaris 58456 R-CFA-8871196 https://reactome.org/PathwayBrowser/#/R-CFA-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Canis familiaris 58456 R-CFA-8874470 https://reactome.org/PathwayBrowser/#/R-CFA-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Canis familiaris 58456 R-CFA-9021627 https://reactome.org/PathwayBrowser/#/R-CFA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris 58456 R-CFA-9647619 https://reactome.org/PathwayBrowser/#/R-CFA-9647619 GSDMD forms ring‐shaped oligomers IEA Canis familiaris 58456 R-CFA-9647631 https://reactome.org/PathwayBrowser/#/R-CFA-9647631 GSDMD (1-275) binds PIPs IEA Canis familiaris 58456 R-CFA-9647645 https://reactome.org/PathwayBrowser/#/R-CFA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Canis familiaris 58456 R-CFA-9647660 https://reactome.org/PathwayBrowser/#/R-CFA-9647660 GSDME (1-270) binds PIPs IEA Canis familiaris 58456 R-CFA-9657599 https://reactome.org/PathwayBrowser/#/R-CFA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Canis familiaris 58456 R-CFA-9657603 https://reactome.org/PathwayBrowser/#/R-CFA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Canis familiaris 58456 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 58456 R-CFA-9657608 https://reactome.org/PathwayBrowser/#/R-CFA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Canis familiaris 58456 R-CFA-9710254 https://reactome.org/PathwayBrowser/#/R-CFA-9710254 GSDME oligomerizes IEA Canis familiaris 58456 R-DDI-111879 https://reactome.org/PathwayBrowser/#/R-DDI-111879 PIP2 hydrolysis IEA Dictyostelium discoideum 58456 R-DDI-114688 https://reactome.org/PathwayBrowser/#/R-DDI-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Dictyostelium discoideum 58456 R-DDI-114689 https://reactome.org/PathwayBrowser/#/R-DDI-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Dictyostelium discoideum 58456 R-DDI-1675776 https://reactome.org/PathwayBrowser/#/R-DDI-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Dictyostelium discoideum 58456 R-DDI-1675824 https://reactome.org/PathwayBrowser/#/R-DDI-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Dictyostelium discoideum 58456 R-DDI-1676048 https://reactome.org/PathwayBrowser/#/R-DDI-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Dictyostelium discoideum 58456 R-DDI-1676082 https://reactome.org/PathwayBrowser/#/R-DDI-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Dictyostelium discoideum 58456 R-DDI-1676177 https://reactome.org/PathwayBrowser/#/R-DDI-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Dictyostelium discoideum 58456 R-DDI-1855177 https://reactome.org/PathwayBrowser/#/R-DDI-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Dictyostelium discoideum 58456 R-DDI-1855214 https://reactome.org/PathwayBrowser/#/R-DDI-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Dictyostelium discoideum 58456 R-DDI-1855221 https://reactome.org/PathwayBrowser/#/R-DDI-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Dictyostelium discoideum 58456 R-DDI-199456 https://reactome.org/PathwayBrowser/#/R-DDI-199456 PTEN dephosphorylates PIP3 IEA Dictyostelium discoideum 58456 R-DDI-202354 https://reactome.org/PathwayBrowser/#/R-DDI-202354 Translocation of PLC-gamma1 to PIP2 IEA Dictyostelium discoideum 58456 R-DDI-202407 https://reactome.org/PathwayBrowser/#/R-DDI-202407 PLC-gamma1 hydrolyses PIP2 IEA Dictyostelium discoideum 58456 R-DDI-2029466 https://reactome.org/PathwayBrowser/#/R-DDI-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Dictyostelium discoideum 58456 R-DDI-2197690 https://reactome.org/PathwayBrowser/#/R-DDI-2197690 Detachment of WASP/WAVE IEA Dictyostelium discoideum 58456 R-DDI-2219524 https://reactome.org/PathwayBrowser/#/R-DDI-2219524 PDPK1 binds PIP2 IEA Dictyostelium discoideum 58456 R-DDI-392300 https://reactome.org/PathwayBrowser/#/R-DDI-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Dictyostelium discoideum 58456 R-DDI-399998 https://reactome.org/PathwayBrowser/#/R-DDI-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Dictyostelium discoideum 58456 R-DDI-437162 https://reactome.org/PathwayBrowser/#/R-DDI-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Dictyostelium discoideum 58456 R-DDI-5607735 https://reactome.org/PathwayBrowser/#/R-DDI-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Dictyostelium discoideum 58456 R-DDI-6811522 https://reactome.org/PathwayBrowser/#/R-DDI-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Dictyostelium discoideum 58456 R-DDI-8849969 https://reactome.org/PathwayBrowser/#/R-DDI-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Dictyostelium discoideum 58456 R-DDI-8856813 https://reactome.org/PathwayBrowser/#/R-DDI-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Dictyostelium discoideum 58456 R-DDI-8868066 https://reactome.org/PathwayBrowser/#/R-DDI-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Dictyostelium discoideum 58456 R-DDI-8868072 https://reactome.org/PathwayBrowser/#/R-DDI-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Dictyostelium discoideum 58456 R-DDI-8871196 https://reactome.org/PathwayBrowser/#/R-DDI-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Dictyostelium discoideum 58456 R-DME-109699 https://reactome.org/PathwayBrowser/#/R-DME-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-110453 https://reactome.org/PathwayBrowser/#/R-DME-110453 Phosphorylation of PIP2 to PIP3 by Dp110 TAS Drosophila melanogaster 58456 R-DME-110459 https://reactome.org/PathwayBrowser/#/R-DME-110459 PIP3 dephosphorylated to PIP2 by DPTEN TAS Drosophila melanogaster 58456 R-DME-111879 https://reactome.org/PathwayBrowser/#/R-DME-111879 PIP2 hydrolysis IEA Drosophila melanogaster 58456 R-DME-114688 https://reactome.org/PathwayBrowser/#/R-DME-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Drosophila melanogaster 58456 R-DME-114689 https://reactome.org/PathwayBrowser/#/R-DME-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Drosophila melanogaster 58456 R-DME-1250370 https://reactome.org/PathwayBrowser/#/R-DME-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Drosophila melanogaster 58456 R-DME-1250462 https://reactome.org/PathwayBrowser/#/R-DME-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Drosophila melanogaster 58456 R-DME-1306957 https://reactome.org/PathwayBrowser/#/R-DME-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Drosophila melanogaster 58456 R-DME-1306979 https://reactome.org/PathwayBrowser/#/R-DME-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Drosophila melanogaster 58456 R-DME-1675776 https://reactome.org/PathwayBrowser/#/R-DME-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Drosophila melanogaster 58456 R-DME-1675824 https://reactome.org/PathwayBrowser/#/R-DME-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Drosophila melanogaster 58456 R-DME-1676048 https://reactome.org/PathwayBrowser/#/R-DME-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Drosophila melanogaster 58456 R-DME-1676082 https://reactome.org/PathwayBrowser/#/R-DME-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Drosophila melanogaster 58456 R-DME-1676177 https://reactome.org/PathwayBrowser/#/R-DME-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Drosophila melanogaster 58456 R-DME-177939 https://reactome.org/PathwayBrowser/#/R-DME-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Drosophila melanogaster 58456 R-DME-1855177 https://reactome.org/PathwayBrowser/#/R-DME-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Drosophila melanogaster 58456 R-DME-1855214 https://reactome.org/PathwayBrowser/#/R-DME-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Drosophila melanogaster 58456 R-DME-1855221 https://reactome.org/PathwayBrowser/#/R-DME-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Drosophila melanogaster 58456 R-DME-186800 https://reactome.org/PathwayBrowser/#/R-DME-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-198266 https://reactome.org/PathwayBrowser/#/R-DME-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Drosophila melanogaster 58456 R-DME-199456 https://reactome.org/PathwayBrowser/#/R-DME-199456 PTEN dephosphorylates PIP3 IEA Drosophila melanogaster 58456 R-DME-201510 https://reactome.org/PathwayBrowser/#/R-DME-201510 PI3K synthesizes PIP3 downstream of ALK IEA Drosophila melanogaster 58456 R-DME-202354 https://reactome.org/PathwayBrowser/#/R-DME-202354 Translocation of PLC-gamma1 to PIP2 IEA Drosophila melanogaster 58456 R-DME-202407 https://reactome.org/PathwayBrowser/#/R-DME-202407 PLC-gamma1 hydrolyses PIP2 IEA Drosophila melanogaster 58456 R-DME-2029466 https://reactome.org/PathwayBrowser/#/R-DME-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Drosophila melanogaster 58456 R-DME-2045911 https://reactome.org/PathwayBrowser/#/R-DME-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Drosophila melanogaster 58456 R-DME-2076220 https://reactome.org/PathwayBrowser/#/R-DME-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Drosophila melanogaster 58456 R-DME-2197690 https://reactome.org/PathwayBrowser/#/R-DME-2197690 Detachment of WASP/WAVE IEA Drosophila melanogaster 58456 R-DME-2219524 https://reactome.org/PathwayBrowser/#/R-DME-2219524 PDPK1 binds PIP2 IEA Drosophila melanogaster 58456 R-DME-2316434 https://reactome.org/PathwayBrowser/#/R-DME-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-2730847 https://reactome.org/PathwayBrowser/#/R-DME-2730847 Hydrolysis of PIP2 by PLCG IEA Drosophila melanogaster 58456 R-DME-2730870 https://reactome.org/PathwayBrowser/#/R-DME-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Drosophila melanogaster 58456 R-DME-2750187 https://reactome.org/PathwayBrowser/#/R-DME-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Drosophila melanogaster 58456 R-DME-354060 https://reactome.org/PathwayBrowser/#/R-DME-354060 Translocation of RIAM to plasma membrane IEA Drosophila melanogaster 58456 R-DME-354077 https://reactome.org/PathwayBrowser/#/R-DME-354077 Integrin alphaIIb beta3 activation IEA Drosophila melanogaster 58456 R-DME-354097 https://reactome.org/PathwayBrowser/#/R-DME-354097 Activation of Talin IEA Drosophila melanogaster 58456 R-DME-354149 https://reactome.org/PathwayBrowser/#/R-DME-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Drosophila melanogaster 58456 R-DME-374662 https://reactome.org/PathwayBrowser/#/R-DME-374662 Translocation of Ezrin to plasma membrane IEA Drosophila melanogaster 58456 R-DME-374663 https://reactome.org/PathwayBrowser/#/R-DME-374663 DCC interaction with Ezrin IEA Drosophila melanogaster 58456 R-DME-374664 https://reactome.org/PathwayBrowser/#/R-DME-374664 Phosphorylation and activation of Ezrin IEA Drosophila melanogaster 58456 R-DME-3772436 https://reactome.org/PathwayBrowser/#/R-DME-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Drosophila melanogaster 58456 R-DME-377640 https://reactome.org/PathwayBrowser/#/R-DME-377640 Autophosphorylation of SRC IEA Drosophila melanogaster 58456 R-DME-377641 https://reactome.org/PathwayBrowser/#/R-DME-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Drosophila melanogaster 58456 R-DME-377643 https://reactome.org/PathwayBrowser/#/R-DME-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Drosophila melanogaster 58456 R-DME-377644 https://reactome.org/PathwayBrowser/#/R-DME-377644 Release of CSK from SRC IEA Drosophila melanogaster 58456 R-DME-392300 https://reactome.org/PathwayBrowser/#/R-DME-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-3928595 https://reactome.org/PathwayBrowser/#/R-DME-3928595 N-WASP binds ARP2/3 and G-actin IEA Drosophila melanogaster 58456 R-DME-3928601 https://reactome.org/PathwayBrowser/#/R-DME-3928601 CDC42 and PIP2 bind WASL, activating it IEA Drosophila melanogaster 58456 R-DME-398193 https://reactome.org/PathwayBrowser/#/R-DME-398193 PLC beta-mediated PIP2 hydrolysis IEA Drosophila melanogaster 58456 R-DME-399998 https://reactome.org/PathwayBrowser/#/R-DME-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Drosophila melanogaster 58456 R-DME-429415 https://reactome.org/PathwayBrowser/#/R-DME-429415 SYK binds to integrin alphaIIb beta3 IEA Drosophila melanogaster 58456 R-DME-429441 https://reactome.org/PathwayBrowser/#/R-DME-429441 SYK activation by SRC IEA Drosophila melanogaster 58456 R-DME-432096 https://reactome.org/PathwayBrowser/#/R-DME-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Drosophila melanogaster 58456 R-DME-437162 https://reactome.org/PathwayBrowser/#/R-DME-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-442273 https://reactome.org/PathwayBrowser/#/R-DME-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Drosophila melanogaster 58456 R-DME-443905 https://reactome.org/PathwayBrowser/#/R-DME-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Drosophila melanogaster 58456 R-DME-443910 https://reactome.org/PathwayBrowser/#/R-DME-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Drosophila melanogaster 58456 R-DME-5218819 https://reactome.org/PathwayBrowser/#/R-DME-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-5607735 https://reactome.org/PathwayBrowser/#/R-DME-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Drosophila melanogaster 58456 R-DME-5654690 https://reactome.org/PathwayBrowser/#/R-DME-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-5654692 https://reactome.org/PathwayBrowser/#/R-DME-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-5654697 https://reactome.org/PathwayBrowser/#/R-DME-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-5654701 https://reactome.org/PathwayBrowser/#/R-DME-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-5654705 https://reactome.org/PathwayBrowser/#/R-DME-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-5654709 https://reactome.org/PathwayBrowser/#/R-DME-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-5654714 https://reactome.org/PathwayBrowser/#/R-DME-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-5654717 https://reactome.org/PathwayBrowser/#/R-DME-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-5672972 https://reactome.org/PathwayBrowser/#/R-DME-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Drosophila melanogaster 58456 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 58456 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 58456 R-DME-5672980 https://reactome.org/PathwayBrowser/#/R-DME-5672980 Dissociation of RAS:RAF complex IEA Drosophila melanogaster 58456 R-DME-6810410 https://reactome.org/PathwayBrowser/#/R-DME-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Drosophila melanogaster 58456 R-DME-6811522 https://reactome.org/PathwayBrowser/#/R-DME-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Drosophila melanogaster 58456 R-DME-8849969 https://reactome.org/PathwayBrowser/#/R-DME-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Drosophila melanogaster 58456 R-DME-8856813 https://reactome.org/PathwayBrowser/#/R-DME-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Drosophila melanogaster 58456 R-DME-8866283 https://reactome.org/PathwayBrowser/#/R-DME-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Drosophila melanogaster 58456 R-DME-8867041 https://reactome.org/PathwayBrowser/#/R-DME-8867041 EGFR phosphorylates EPS15 IEA Drosophila melanogaster 58456 R-DME-8867044 https://reactome.org/PathwayBrowser/#/R-DME-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Drosophila melanogaster 58456 R-DME-8867047 https://reactome.org/PathwayBrowser/#/R-DME-8867047 PTPN3 dephosphorylates EPS15 IEA Drosophila melanogaster 58456 R-DME-8867754 https://reactome.org/PathwayBrowser/#/R-DME-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Drosophila melanogaster 58456 R-DME-8867756 https://reactome.org/PathwayBrowser/#/R-DME-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Drosophila melanogaster 58456 R-DME-8868066 https://reactome.org/PathwayBrowser/#/R-DME-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Drosophila melanogaster 58456 R-DME-8868071 https://reactome.org/PathwayBrowser/#/R-DME-8868071 Clathrin recruits PIK3C2A IEA Drosophila melanogaster 58456 R-DME-8868072 https://reactome.org/PathwayBrowser/#/R-DME-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Drosophila melanogaster 58456 R-DME-8868236 https://reactome.org/PathwayBrowser/#/R-DME-8868236 BAR domain proteins recruit dynamin IEA Drosophila melanogaster 58456 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster 58456 R-DME-8868651 https://reactome.org/PathwayBrowser/#/R-DME-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Drosophila melanogaster 58456 R-DME-8871196 https://reactome.org/PathwayBrowser/#/R-DME-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Drosophila melanogaster 58456 R-DME-8874470 https://reactome.org/PathwayBrowser/#/R-DME-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Drosophila melanogaster 58456 R-DME-9021627 https://reactome.org/PathwayBrowser/#/R-DME-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Drosophila melanogaster 58456 R-DME-9657599 https://reactome.org/PathwayBrowser/#/R-DME-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Drosophila melanogaster 58456 R-DME-9657603 https://reactome.org/PathwayBrowser/#/R-DME-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Drosophila melanogaster 58456 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 58456 R-DME-9657608 https://reactome.org/PathwayBrowser/#/R-DME-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Drosophila melanogaster 58456 R-DRE-1250370 https://reactome.org/PathwayBrowser/#/R-DRE-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Danio rerio 58456 R-DRE-1250462 https://reactome.org/PathwayBrowser/#/R-DRE-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Danio rerio 58456 R-DRE-1306979 https://reactome.org/PathwayBrowser/#/R-DRE-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Danio rerio 58456 R-DRE-1433514 https://reactome.org/PathwayBrowser/#/R-DRE-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Danio rerio 58456 R-DRE-1675776 https://reactome.org/PathwayBrowser/#/R-DRE-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Danio rerio 58456 R-DRE-1676048 https://reactome.org/PathwayBrowser/#/R-DRE-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Danio rerio 58456 R-DRE-1676082 https://reactome.org/PathwayBrowser/#/R-DRE-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Danio rerio 58456 R-DRE-177939 https://reactome.org/PathwayBrowser/#/R-DRE-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Danio rerio 58456 R-DRE-1855221 https://reactome.org/PathwayBrowser/#/R-DRE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Danio rerio 58456 R-DRE-186800 https://reactome.org/PathwayBrowser/#/R-DRE-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Danio rerio 58456 R-DRE-199456 https://reactome.org/PathwayBrowser/#/R-DRE-199456 PTEN dephosphorylates PIP3 IEA Danio rerio 58456 R-DRE-201510 https://reactome.org/PathwayBrowser/#/R-DRE-201510 PI3K synthesizes PIP3 downstream of ALK IEA Danio rerio 58456 R-DRE-202354 https://reactome.org/PathwayBrowser/#/R-DRE-202354 Translocation of PLC-gamma1 to PIP2 IEA Danio rerio 58456 R-DRE-202407 https://reactome.org/PathwayBrowser/#/R-DRE-202407 PLC-gamma1 hydrolyses PIP2 IEA Danio rerio 58456 R-DRE-2029466 https://reactome.org/PathwayBrowser/#/R-DRE-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Danio rerio 58456 R-DRE-2045911 https://reactome.org/PathwayBrowser/#/R-DRE-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Danio rerio 58456 R-DRE-2197690 https://reactome.org/PathwayBrowser/#/R-DRE-2197690 Detachment of WASP/WAVE IEA Danio rerio 58456 R-DRE-2219524 https://reactome.org/PathwayBrowser/#/R-DRE-2219524 PDPK1 binds PIP2 IEA Danio rerio 58456 R-DRE-2316434 https://reactome.org/PathwayBrowser/#/R-DRE-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 58456 R-DRE-2731138 https://reactome.org/PathwayBrowser/#/R-DRE-2731138 Syndecan-4 binds PI(4,5)P2 TAS Danio rerio 58456 R-DRE-354060 https://reactome.org/PathwayBrowser/#/R-DRE-354060 Translocation of RIAM to plasma membrane IEA Danio rerio 58456 R-DRE-354149 https://reactome.org/PathwayBrowser/#/R-DRE-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Danio rerio 58456 R-DRE-374662 https://reactome.org/PathwayBrowser/#/R-DRE-374662 Translocation of Ezrin to plasma membrane IEA Danio rerio 58456 R-DRE-374663 https://reactome.org/PathwayBrowser/#/R-DRE-374663 DCC interaction with Ezrin IEA Danio rerio 58456 R-DRE-377640 https://reactome.org/PathwayBrowser/#/R-DRE-377640 Autophosphorylation of SRC IEA Danio rerio 58456 R-DRE-377641 https://reactome.org/PathwayBrowser/#/R-DRE-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Danio rerio 58456 R-DRE-377644 https://reactome.org/PathwayBrowser/#/R-DRE-377644 Release of CSK from SRC IEA Danio rerio 58456 R-DRE-3928595 https://reactome.org/PathwayBrowser/#/R-DRE-3928595 N-WASP binds ARP2/3 and G-actin IEA Danio rerio 58456 R-DRE-3928601 https://reactome.org/PathwayBrowser/#/R-DRE-3928601 CDC42 and PIP2 bind WASL, activating it IEA Danio rerio 58456 R-DRE-418874 https://reactome.org/PathwayBrowser/#/R-DRE-418874 Recruitment and activation of N-WASP by Cdc42 IEA Danio rerio 58456 R-DRE-437162 https://reactome.org/PathwayBrowser/#/R-DRE-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Danio rerio 58456 R-DRE-443905 https://reactome.org/PathwayBrowser/#/R-DRE-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Danio rerio 58456 R-DRE-5218819 https://reactome.org/PathwayBrowser/#/R-DRE-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 58456 R-DRE-5654690 https://reactome.org/PathwayBrowser/#/R-DRE-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio 58456 R-DRE-6805981 https://reactome.org/PathwayBrowser/#/R-DRE-6805981 HMGB1 release from cells IEA Danio rerio 58456 R-DRE-6810410 https://reactome.org/PathwayBrowser/#/R-DRE-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Danio rerio 58456 R-DRE-6811522 https://reactome.org/PathwayBrowser/#/R-DRE-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Danio rerio 58456 R-DRE-8849969 https://reactome.org/PathwayBrowser/#/R-DRE-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Danio rerio 58456 R-DRE-8874470 https://reactome.org/PathwayBrowser/#/R-DRE-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Danio rerio 58456 R-DRE-9647660 https://reactome.org/PathwayBrowser/#/R-DRE-9647660 GSDME (1-270) binds PIPs IEA Danio rerio 58456 R-DRE-9710254 https://reactome.org/PathwayBrowser/#/R-DRE-9710254 GSDME oligomerizes IEA Danio rerio 58456 R-GGA-109699 https://reactome.org/PathwayBrowser/#/R-GGA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus 58456 R-GGA-111879 https://reactome.org/PathwayBrowser/#/R-GGA-111879 PIP2 hydrolysis IEA Gallus gallus 58456 R-GGA-114688 https://reactome.org/PathwayBrowser/#/R-GGA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Gallus gallus 58456 R-GGA-114689 https://reactome.org/PathwayBrowser/#/R-GGA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Gallus gallus 58456 R-GGA-1250370 https://reactome.org/PathwayBrowser/#/R-GGA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Gallus gallus 58456 R-GGA-1250462 https://reactome.org/PathwayBrowser/#/R-GGA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Gallus gallus 58456 R-GGA-1306957 https://reactome.org/PathwayBrowser/#/R-GGA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus 58456 R-GGA-1306979 https://reactome.org/PathwayBrowser/#/R-GGA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Gallus gallus 58456 R-GGA-1433514 https://reactome.org/PathwayBrowser/#/R-GGA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Gallus gallus 58456 R-GGA-1675776 https://reactome.org/PathwayBrowser/#/R-GGA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Gallus gallus 58456 R-GGA-1675824 https://reactome.org/PathwayBrowser/#/R-GGA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Gallus gallus 58456 R-GGA-1676048 https://reactome.org/PathwayBrowser/#/R-GGA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Gallus gallus 58456 R-GGA-1676082 https://reactome.org/PathwayBrowser/#/R-GGA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Gallus gallus 58456 R-GGA-1676177 https://reactome.org/PathwayBrowser/#/R-GGA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Gallus gallus 58456 R-GGA-177939 https://reactome.org/PathwayBrowser/#/R-GGA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Gallus gallus 58456 R-GGA-1855177 https://reactome.org/PathwayBrowser/#/R-GGA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Gallus gallus 58456 R-GGA-1855214 https://reactome.org/PathwayBrowser/#/R-GGA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Gallus gallus 58456 R-GGA-1855221 https://reactome.org/PathwayBrowser/#/R-GGA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Gallus gallus 58456 R-GGA-186800 https://reactome.org/PathwayBrowser/#/R-GGA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-198266 https://reactome.org/PathwayBrowser/#/R-GGA-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Gallus gallus 58456 R-GGA-199456 https://reactome.org/PathwayBrowser/#/R-GGA-199456 PTEN dephosphorylates PIP3 IEA Gallus gallus 58456 R-GGA-201510 https://reactome.org/PathwayBrowser/#/R-GGA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Gallus gallus 58456 R-GGA-202354 https://reactome.org/PathwayBrowser/#/R-GGA-202354 Translocation of PLC-gamma1 to PIP2 IEA Gallus gallus 58456 R-GGA-202365 https://reactome.org/PathwayBrowser/#/R-GGA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-202407 https://reactome.org/PathwayBrowser/#/R-GGA-202407 PLC-gamma1 hydrolyses PIP2 IEA Gallus gallus 58456 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-2029466 https://reactome.org/PathwayBrowser/#/R-GGA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Gallus gallus 58456 R-GGA-2045911 https://reactome.org/PathwayBrowser/#/R-GGA-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Gallus gallus 58456 R-GGA-2197690 https://reactome.org/PathwayBrowser/#/R-GGA-2197690 Detachment of WASP/WAVE IEA Gallus gallus 58456 R-GGA-2197698 https://reactome.org/PathwayBrowser/#/R-GGA-2197698 Src phosphorylate WASP,N-WASP IEA Gallus gallus 58456 R-GGA-2219524 https://reactome.org/PathwayBrowser/#/R-GGA-2219524 PDPK1 binds PIP2 IEA Gallus gallus 58456 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-2559456 https://reactome.org/PathwayBrowser/#/R-GGA-2559456 TIRAP binds PIP2-rich regions in the plasma membrane IEA Gallus gallus 58456 R-GGA-2730847 https://reactome.org/PathwayBrowser/#/R-GGA-2730847 Hydrolysis of PIP2 by PLCG IEA Gallus gallus 58456 R-GGA-2730870 https://reactome.org/PathwayBrowser/#/R-GGA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Gallus gallus 58456 R-GGA-2750187 https://reactome.org/PathwayBrowser/#/R-GGA-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Gallus gallus 58456 R-GGA-354060 https://reactome.org/PathwayBrowser/#/R-GGA-354060 Translocation of RIAM to plasma membrane IEA Gallus gallus 58456 R-GGA-354066 https://reactome.org/PathwayBrowser/#/R-GGA-354066 Translocation of PTK2 to Focal complexes IEA Gallus gallus 58456 R-GGA-354073 https://reactome.org/PathwayBrowser/#/R-GGA-354073 Autophosphorylation of PTK2 at Y397 IEA Gallus gallus 58456 R-GGA-354077 https://reactome.org/PathwayBrowser/#/R-GGA-354077 Integrin alphaIIb beta3 activation IEA Gallus gallus 58456 R-GGA-354087 https://reactome.org/PathwayBrowser/#/R-GGA-354087 Recruitment of GRB2 to p-PTK2 IEA Gallus gallus 58456 R-GGA-354097 https://reactome.org/PathwayBrowser/#/R-GGA-354097 Activation of Talin IEA Gallus gallus 58456 R-GGA-354124 https://reactome.org/PathwayBrowser/#/R-GGA-354124 Phosphorylation of pPTK2 by SRC IEA Gallus gallus 58456 R-GGA-354149 https://reactome.org/PathwayBrowser/#/R-GGA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Gallus gallus 58456 R-GGA-354165 https://reactome.org/PathwayBrowser/#/R-GGA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Gallus gallus 58456 R-GGA-372693 https://reactome.org/PathwayBrowser/#/R-GGA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Gallus gallus 58456 R-GGA-372697 https://reactome.org/PathwayBrowser/#/R-GGA-372697 Crk binding to p130cas IEA Gallus gallus 58456 R-GGA-372705 https://reactome.org/PathwayBrowser/#/R-GGA-372705 Recruitment of BCAR1 to PTK2 complex IEA Gallus gallus 58456 R-GGA-374662 https://reactome.org/PathwayBrowser/#/R-GGA-374662 Translocation of Ezrin to plasma membrane IEA Gallus gallus 58456 R-GGA-3772436 https://reactome.org/PathwayBrowser/#/R-GGA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Gallus gallus 58456 R-GGA-377640 https://reactome.org/PathwayBrowser/#/R-GGA-377640 Autophosphorylation of SRC IEA Gallus gallus 58456 R-GGA-377641 https://reactome.org/PathwayBrowser/#/R-GGA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Gallus gallus 58456 R-GGA-377643 https://reactome.org/PathwayBrowser/#/R-GGA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Gallus gallus 58456 R-GGA-377644 https://reactome.org/PathwayBrowser/#/R-GGA-377644 Release of CSK from SRC IEA Gallus gallus 58456 R-GGA-389158 https://reactome.org/PathwayBrowser/#/R-GGA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-392300 https://reactome.org/PathwayBrowser/#/R-GGA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-3928595 https://reactome.org/PathwayBrowser/#/R-GGA-3928595 N-WASP binds ARP2/3 and G-actin IEA Gallus gallus 58456 R-GGA-3928601 https://reactome.org/PathwayBrowser/#/R-GGA-3928601 CDC42 and PIP2 bind WASL, activating it IEA Gallus gallus 58456 R-GGA-398193 https://reactome.org/PathwayBrowser/#/R-GGA-398193 PLC beta-mediated PIP2 hydrolysis IEA Gallus gallus 58456 R-GGA-399998 https://reactome.org/PathwayBrowser/#/R-GGA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Gallus gallus 58456 R-GGA-429415 https://reactome.org/PathwayBrowser/#/R-GGA-429415 SYK binds to integrin alphaIIb beta3 IEA Gallus gallus 58456 R-GGA-429441 https://reactome.org/PathwayBrowser/#/R-GGA-429441 SYK activation by SRC IEA Gallus gallus 58456 R-GGA-432096 https://reactome.org/PathwayBrowser/#/R-GGA-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Gallus gallus 58456 R-GGA-437162 https://reactome.org/PathwayBrowser/#/R-GGA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-443905 https://reactome.org/PathwayBrowser/#/R-GGA-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Gallus gallus 58456 R-GGA-443910 https://reactome.org/PathwayBrowser/#/R-GGA-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Gallus gallus 58456 R-GGA-449058 https://reactome.org/PathwayBrowser/#/R-GGA-449058 Interleukin-1 family are secreted IEA Gallus gallus 58456 R-GGA-5218819 https://reactome.org/PathwayBrowser/#/R-GGA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-5607735 https://reactome.org/PathwayBrowser/#/R-GGA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Gallus gallus 58456 R-GGA-5654690 https://reactome.org/PathwayBrowser/#/R-GGA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-5654692 https://reactome.org/PathwayBrowser/#/R-GGA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-5654697 https://reactome.org/PathwayBrowser/#/R-GGA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-5654701 https://reactome.org/PathwayBrowser/#/R-GGA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-5654705 https://reactome.org/PathwayBrowser/#/R-GGA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-5654709 https://reactome.org/PathwayBrowser/#/R-GGA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-5654714 https://reactome.org/PathwayBrowser/#/R-GGA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-5654717 https://reactome.org/PathwayBrowser/#/R-GGA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus 58456 R-GGA-5672972 https://reactome.org/PathwayBrowser/#/R-GGA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Gallus gallus 58456 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 58456 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 58456 R-GGA-5672980 https://reactome.org/PathwayBrowser/#/R-GGA-5672980 Dissociation of RAS:RAF complex IEA Gallus gallus 58456 R-GGA-6805981 https://reactome.org/PathwayBrowser/#/R-GGA-6805981 HMGB1 release from cells IEA Gallus gallus 58456 R-GGA-6811522 https://reactome.org/PathwayBrowser/#/R-GGA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Gallus gallus 58456 R-GGA-8849969 https://reactome.org/PathwayBrowser/#/R-GGA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Gallus gallus 58456 R-GGA-8852019 https://reactome.org/PathwayBrowser/#/R-GGA-8852019 MET bound PI3K generates PIP3 IEA Gallus gallus 58456 R-GGA-8856813 https://reactome.org/PathwayBrowser/#/R-GGA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Gallus gallus 58456 R-GGA-8867041 https://reactome.org/PathwayBrowser/#/R-GGA-8867041 EGFR phosphorylates EPS15 IEA Gallus gallus 58456 R-GGA-8867047 https://reactome.org/PathwayBrowser/#/R-GGA-8867047 PTPN3 dephosphorylates EPS15 IEA Gallus gallus 58456 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus 58456 R-GGA-8868066 https://reactome.org/PathwayBrowser/#/R-GGA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Gallus gallus 58456 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus 58456 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus 58456 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus 58456 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus 58456 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus 58456 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus 58456 R-GGA-8871196 https://reactome.org/PathwayBrowser/#/R-GGA-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Gallus gallus 58456 R-GGA-8874470 https://reactome.org/PathwayBrowser/#/R-GGA-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Gallus gallus 58456 R-GGA-9647619 https://reactome.org/PathwayBrowser/#/R-GGA-9647619 GSDMD forms ring‐shaped oligomers IEA Gallus gallus 58456 R-GGA-9647631 https://reactome.org/PathwayBrowser/#/R-GGA-9647631 GSDMD (1-275) binds PIPs IEA Gallus gallus 58456 R-GGA-9647645 https://reactome.org/PathwayBrowser/#/R-GGA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Gallus gallus 58456 R-GGA-9647660 https://reactome.org/PathwayBrowser/#/R-GGA-9647660 GSDME (1-270) binds PIPs IEA Gallus gallus 58456 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus 58456 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus 58456 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 58456 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus 58456 R-GGA-9710254 https://reactome.org/PathwayBrowser/#/R-GGA-9710254 GSDME oligomerizes IEA Gallus gallus 58456 R-HSA-109699 https://reactome.org/PathwayBrowser/#/R-HSA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-1112666 https://reactome.org/PathwayBrowser/#/R-HSA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate TAS Homo sapiens 58456 R-HSA-111879 https://reactome.org/PathwayBrowser/#/R-HSA-111879 PIP2 hydrolysis TAS Homo sapiens 58456 R-HSA-114688 https://reactome.org/PathwayBrowser/#/R-HSA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 TAS Homo sapiens 58456 R-HSA-114689 https://reactome.org/PathwayBrowser/#/R-HSA-114689 PLC gamma 2-mediated PIP2 hydrolysis TAS Homo sapiens 58456 R-HSA-1226014 https://reactome.org/PathwayBrowser/#/R-HSA-1226014 Conversion of PIP2 to PIP3 by PI3K bound to ligand-responsive p-6Y-EGFR mutants TAS Homo sapiens 58456 R-HSA-1250370 https://reactome.org/PathwayBrowser/#/R-HSA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers TAS Homo sapiens 58456 R-HSA-1250462 https://reactome.org/PathwayBrowser/#/R-HSA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 TAS Homo sapiens 58456 R-HSA-1306957 https://reactome.org/PathwayBrowser/#/R-HSA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR TAS Homo sapiens 58456 R-HSA-1306979 https://reactome.org/PathwayBrowser/#/R-HSA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 TAS Homo sapiens 58456 R-HSA-1433514 https://reactome.org/PathwayBrowser/#/R-HSA-1433514 Synthesis of PIP3 from PIP2 by PI3K TAS Homo sapiens 58456 R-HSA-166072 https://reactome.org/PathwayBrowser/#/R-HSA-166072 MyD88 forms a complex with TIRAP:activated TLR2/4 TAS Homo sapiens 58456 R-HSA-166082 https://reactome.org/PathwayBrowser/#/R-HSA-166082 IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex TAS Homo sapiens 58456 R-HSA-166091 https://reactome.org/PathwayBrowser/#/R-HSA-166091 IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex TAS Homo sapiens 58456 R-HSA-166119 https://reactome.org/PathwayBrowser/#/R-HSA-166119 First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal TAS Homo sapiens 58456 R-HSA-166284 https://reactome.org/PathwayBrowser/#/R-HSA-166284 Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP TAS Homo sapiens 58456 R-HSA-166286 https://reactome.org/PathwayBrowser/#/R-HSA-166286 Multiple IRAK1 autophosphorylation steps TAS Homo sapiens 58456 R-HSA-166362 https://reactome.org/PathwayBrowser/#/R-HSA-166362 Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 58456 R-HSA-166363 https://reactome.org/PathwayBrowser/#/R-HSA-166363 TRAF6 binds to hp- IRAK1 TAS Homo sapiens 58456 R-HSA-1675776 https://reactome.org/PathwayBrowser/#/R-HSA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane TAS Homo sapiens 58456 R-HSA-1675824 https://reactome.org/PathwayBrowser/#/R-HSA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane TAS Homo sapiens 58456 R-HSA-1676048 https://reactome.org/PathwayBrowser/#/R-HSA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane TAS Homo sapiens 58456 R-HSA-1676082 https://reactome.org/PathwayBrowser/#/R-HSA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane TAS Homo sapiens 58456 R-HSA-1676177 https://reactome.org/PathwayBrowser/#/R-HSA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane TAS Homo sapiens 58456 R-HSA-167686 https://reactome.org/PathwayBrowser/#/R-HSA-167686 Active PLCG1 hydrolyses PIP2 IEA Homo sapiens 58456 R-HSA-177939 https://reactome.org/PathwayBrowser/#/R-HSA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) TAS Homo sapiens 58456 R-HSA-1839091 https://reactome.org/PathwayBrowser/#/R-HSA-1839091 Cytosolic FGFR1 fusion protein-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-1839107 https://reactome.org/PathwayBrowser/#/R-HSA-1839107 BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3. TAS Homo sapiens 58456 R-HSA-1855177 https://reactome.org/PathwayBrowser/#/R-HSA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane TAS Homo sapiens 58456 R-HSA-1855214 https://reactome.org/PathwayBrowser/#/R-HSA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane TAS Homo sapiens 58456 R-HSA-1855221 https://reactome.org/PathwayBrowser/#/R-HSA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane TAS Homo sapiens 58456 R-HSA-186800 https://reactome.org/PathwayBrowser/#/R-HSA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-198266 https://reactome.org/PathwayBrowser/#/R-HSA-198266 PI3K produces PIP3 and other phosphatidyl inositides TAS Homo sapiens 58456 R-HSA-199456 https://reactome.org/PathwayBrowser/#/R-HSA-199456 PTEN dephosphorylates PIP3 TAS Homo sapiens 58456 R-HSA-201510 https://reactome.org/PathwayBrowser/#/R-HSA-201510 PI3K synthesizes PIP3 downstream of ALK TAS Homo sapiens 58456 R-HSA-202354 https://reactome.org/PathwayBrowser/#/R-HSA-202354 Translocation of PLC-gamma1 to PIP2 TAS Homo sapiens 58456 R-HSA-202365 https://reactome.org/PathwayBrowser/#/R-HSA-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-202407 https://reactome.org/PathwayBrowser/#/R-HSA-202407 PLC-gamma1 hydrolyses PIP2 TAS Homo sapiens 58456 R-HSA-2029271 https://reactome.org/PathwayBrowser/#/R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-2029466 https://reactome.org/PathwayBrowser/#/R-HSA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin TAS Homo sapiens 58456 R-HSA-2045911 https://reactome.org/PathwayBrowser/#/R-HSA-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 TAS Homo sapiens 58456 R-HSA-2076220 https://reactome.org/PathwayBrowser/#/R-HSA-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 TAS Homo sapiens 58456 R-HSA-2197690 https://reactome.org/PathwayBrowser/#/R-HSA-2197690 Detachment of WASP/WAVE TAS Homo sapiens 58456 R-HSA-2197691 https://reactome.org/PathwayBrowser/#/R-HSA-2197691 WIP binds WASP,N-WASP, activating them TAS Homo sapiens 58456 R-HSA-2197698 https://reactome.org/PathwayBrowser/#/R-HSA-2197698 Src phosphorylate WASP,N-WASP TAS Homo sapiens 58456 R-HSA-2201316 https://reactome.org/PathwayBrowser/#/R-HSA-2201316 Activated TLR2/4 interacts with MAL (TIRAP) TAS Homo sapiens 58456 R-HSA-2201322 https://reactome.org/PathwayBrowser/#/R-HSA-2201322 TIRAP is phosphorylated by BTK TAS Homo sapiens 58456 R-HSA-2219524 https://reactome.org/PathwayBrowser/#/R-HSA-2219524 PDPK1 binds PIP2 TAS Homo sapiens 58456 R-HSA-2219536 https://reactome.org/PathwayBrowser/#/R-HSA-2219536 AKT1 E17K mutant binds PIP2 TAS Homo sapiens 58456 R-HSA-2243937 https://reactome.org/PathwayBrowser/#/R-HSA-2243937 PIP2-bound p-S473-AKT1 mutant binds PIP2-bound PDPK1 TAS Homo sapiens 58456 R-HSA-2243938 https://reactome.org/PathwayBrowser/#/R-HSA-2243938 AKT1 E17K mutant is phosphorylated by TORC2 complex TAS Homo sapiens 58456 R-HSA-2243942 https://reactome.org/PathwayBrowser/#/R-HSA-2243942 PDPK1 phosphorylates AKT1 E17K mutant TAS Homo sapiens 58456 R-HSA-2262775 https://reactome.org/PathwayBrowser/#/R-HSA-2262775 Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 58456 R-HSA-2262777 https://reactome.org/PathwayBrowser/#/R-HSA-2262777 TRAF6 binds to p-IRAK2 TAS Homo sapiens 58456 R-HSA-2316434 https://reactome.org/PathwayBrowser/#/R-HSA-2316434 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-2394007 https://reactome.org/PathwayBrowser/#/R-HSA-2394007 PI3K gain of function mutants phosphorylate PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-2424480 https://reactome.org/PathwayBrowser/#/R-HSA-2424480 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-2559414 https://reactome.org/PathwayBrowser/#/R-HSA-2559414 Activated TLR2/4:TIRAP interacts with BTK TAS Homo sapiens 58456 R-HSA-2559456 https://reactome.org/PathwayBrowser/#/R-HSA-2559456 TIRAP binds PIP2-rich regions in the plasma membrane TAS Homo sapiens 58456 R-HSA-2730847 https://reactome.org/PathwayBrowser/#/R-HSA-2730847 Hydrolysis of PIP2 by PLCG TAS Homo sapiens 58456 R-HSA-2730870 https://reactome.org/PathwayBrowser/#/R-HSA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K TAS Homo sapiens 58456 R-HSA-2731147 https://reactome.org/PathwayBrowser/#/R-HSA-2731147 Syndecan-4 binds PI(4,5)P2 IEA Homo sapiens 58456 R-HSA-2750187 https://reactome.org/PathwayBrowser/#/R-HSA-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG TAS Homo sapiens 58456 R-HSA-354060 https://reactome.org/PathwayBrowser/#/R-HSA-354060 Translocation of RIAM to plasma membrane TAS Homo sapiens 58456 R-HSA-354066 https://reactome.org/PathwayBrowser/#/R-HSA-354066 Translocation of PTK2 to Focal complexes TAS Homo sapiens 58456 R-HSA-354073 https://reactome.org/PathwayBrowser/#/R-HSA-354073 Autophosphorylation of PTK2 at Y397 TAS Homo sapiens 58456 R-HSA-354077 https://reactome.org/PathwayBrowser/#/R-HSA-354077 Integrin alphaIIb beta3 activation TAS Homo sapiens 58456 R-HSA-354087 https://reactome.org/PathwayBrowser/#/R-HSA-354087 Recruitment of GRB2 to p-PTK2 TAS Homo sapiens 58456 R-HSA-354097 https://reactome.org/PathwayBrowser/#/R-HSA-354097 Activation of Talin TAS Homo sapiens 58456 R-HSA-354124 https://reactome.org/PathwayBrowser/#/R-HSA-354124 Phosphorylation of pPTK2 by SRC TAS Homo sapiens 58456 R-HSA-354149 https://reactome.org/PathwayBrowser/#/R-HSA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen TAS Homo sapiens 58456 R-HSA-354165 https://reactome.org/PathwayBrowser/#/R-HSA-354165 Interaction of SOS with GRB2 bound to FADK1 TAS Homo sapiens 58456 R-HSA-372693 https://reactome.org/PathwayBrowser/#/R-HSA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex TAS Homo sapiens 58456 R-HSA-372697 https://reactome.org/PathwayBrowser/#/R-HSA-372697 Crk binding to p130cas TAS Homo sapiens 58456 R-HSA-372705 https://reactome.org/PathwayBrowser/#/R-HSA-372705 Recruitment of BCAR1 to PTK2 complex TAS Homo sapiens 58456 R-HSA-374662 https://reactome.org/PathwayBrowser/#/R-HSA-374662 Translocation of Ezrin to plasma membrane TAS Homo sapiens 58456 R-HSA-374663 https://reactome.org/PathwayBrowser/#/R-HSA-374663 DCC interaction with Ezrin TAS Homo sapiens 58456 R-HSA-374664 https://reactome.org/PathwayBrowser/#/R-HSA-374664 Phosphorylation and activation of Ezrin TAS Homo sapiens 58456 R-HSA-374677 https://reactome.org/PathwayBrowser/#/R-HSA-374677 L1 binds ERM family members IEA Homo sapiens 58456 R-HSA-374680 https://reactome.org/PathwayBrowser/#/R-HSA-374680 L1 trans-homophilic interaction TAS Homo sapiens 58456 R-HSA-3772436 https://reactome.org/PathwayBrowser/#/R-HSA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 TAS Homo sapiens 58456 R-HSA-377640 https://reactome.org/PathwayBrowser/#/R-HSA-377640 Autophosphorylation of SRC TAS Homo sapiens 58456 R-HSA-377641 https://reactome.org/PathwayBrowser/#/R-HSA-377641 Clustering of Integrin alphaIIb beta3 complexes TAS Homo sapiens 58456 R-HSA-377643 https://reactome.org/PathwayBrowser/#/R-HSA-377643 Dephosphorylation of inactive SRC by PTPB1 TAS Homo sapiens 58456 R-HSA-377644 https://reactome.org/PathwayBrowser/#/R-HSA-377644 Release of CSK from SRC TAS Homo sapiens 58456 R-HSA-389158 https://reactome.org/PathwayBrowser/#/R-HSA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-392300 https://reactome.org/PathwayBrowser/#/R-HSA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-3928595 https://reactome.org/PathwayBrowser/#/R-HSA-3928595 N-WASP binds ARP2/3 and G-actin TAS Homo sapiens 58456 R-HSA-3928601 https://reactome.org/PathwayBrowser/#/R-HSA-3928601 CDC42 and PIP2 bind WASL, activating it TAS Homo sapiens 58456 R-HSA-398193 https://reactome.org/PathwayBrowser/#/R-HSA-398193 PLC beta-mediated PIP2 hydrolysis TAS Homo sapiens 58456 R-HSA-399998 https://reactome.org/PathwayBrowser/#/R-HSA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate TAS Homo sapiens 58456 R-HSA-418874 https://reactome.org/PathwayBrowser/#/R-HSA-418874 Recruitment and activation of N-WASP by Cdc42 TAS Homo sapiens 58456 R-HSA-429415 https://reactome.org/PathwayBrowser/#/R-HSA-429415 SYK binds to integrin alphaIIb beta3 TAS Homo sapiens 58456 R-HSA-429441 https://reactome.org/PathwayBrowser/#/R-HSA-429441 SYK activation by SRC TAS Homo sapiens 58456 R-HSA-432096 https://reactome.org/PathwayBrowser/#/R-HSA-432096 Activated integrin alphaIIb beta3 binds SHC1 TAS Homo sapiens 58456 R-HSA-434633 https://reactome.org/PathwayBrowser/#/R-HSA-434633 PIP2 binds inhibiting VAV IEA Homo sapiens 58456 R-HSA-437162 https://reactome.org/PathwayBrowser/#/R-HSA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-442273 https://reactome.org/PathwayBrowser/#/R-HSA-442273 VAV1 is a GEF for Rho/Rac family GTPases TAS Homo sapiens 58456 R-HSA-442586 https://reactome.org/PathwayBrowser/#/R-HSA-442586 Activation of WASP and N-WASP by CDC42 IEA Homo sapiens 58456 R-HSA-442592 https://reactome.org/PathwayBrowser/#/R-HSA-442592 WASPs or WAVEs activate the ARP2/3 complex IEA Homo sapiens 58456 R-HSA-442739 https://reactome.org/PathwayBrowser/#/R-HSA-442739 PDPK1 phosphorylates RSKs IEA Homo sapiens 58456 R-HSA-443779 https://reactome.org/PathwayBrowser/#/R-HSA-443779 Linkage of L1 with treadmilling F-actin TAS Homo sapiens 58456 R-HSA-443905 https://reactome.org/PathwayBrowser/#/R-HSA-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow TAS Homo sapiens 58456 R-HSA-443910 https://reactome.org/PathwayBrowser/#/R-HSA-443910 SHC1 dissociates from integrin alphaIIb beta3 TAS Homo sapiens 58456 R-HSA-445089 https://reactome.org/PathwayBrowser/#/R-HSA-445089 Dephosphorylation of pL1 (Y1176) TAS Homo sapiens 58456 R-HSA-449058 https://reactome.org/PathwayBrowser/#/R-HSA-449058 Interleukin-1 family are secreted TAS Homo sapiens 58456 R-HSA-5218819 https://reactome.org/PathwayBrowser/#/R-HSA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5602353 https://reactome.org/PathwayBrowser/#/R-HSA-5602353 Defective IRAK4 variants do not bind MyD88:MAL:BTK:activated TLR2/4 TAS Homo sapiens 58456 R-HSA-5602383 https://reactome.org/PathwayBrowser/#/R-HSA-5602383 Defective MyD88 does not oligomerize within the activated TLR2/4 complex TAS Homo sapiens 58456 R-HSA-5602606 https://reactome.org/PathwayBrowser/#/R-HSA-5602606 Defective MyD88 does not bind MAL(TIRAP):TLR2/4 TAS Homo sapiens 58456 R-HSA-5602672 https://reactome.org/PathwayBrowser/#/R-HSA-5602672 Defective IRAK4 does not bind MyD88 within the TLR2/4 complex TAS Homo sapiens 58456 R-HSA-5607735 https://reactome.org/PathwayBrowser/#/R-HSA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 TAS Homo sapiens 58456 R-HSA-5620975 https://reactome.org/PathwayBrowser/#/R-HSA-5620975 MLKL binds PIPs TAS Homo sapiens 58456 R-HSA-5637801 https://reactome.org/PathwayBrowser/#/R-HSA-5637801 Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII TAS Homo sapiens 58456 R-HSA-5654690 https://reactome.org/PathwayBrowser/#/R-HSA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5654692 https://reactome.org/PathwayBrowser/#/R-HSA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5654697 https://reactome.org/PathwayBrowser/#/R-HSA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5654701 https://reactome.org/PathwayBrowser/#/R-HSA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5654705 https://reactome.org/PathwayBrowser/#/R-HSA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5654709 https://reactome.org/PathwayBrowser/#/R-HSA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5654714 https://reactome.org/PathwayBrowser/#/R-HSA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5654717 https://reactome.org/PathwayBrowser/#/R-HSA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5655235 https://reactome.org/PathwayBrowser/#/R-HSA-5655235 Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5655289 https://reactome.org/PathwayBrowser/#/R-HSA-5655289 Activated FGFR3 point, translocation and fusion mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5655290 https://reactome.org/PathwayBrowser/#/R-HSA-5655290 Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5655323 https://reactome.org/PathwayBrowser/#/R-HSA-5655323 Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-5672972 https://reactome.org/PathwayBrowser/#/R-HSA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex TAS Homo sapiens 58456 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 58456 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 58456 R-HSA-5672980 https://reactome.org/PathwayBrowser/#/R-HSA-5672980 Dissociation of RAS:RAF complex TAS Homo sapiens 58456 R-HSA-622382 https://reactome.org/PathwayBrowser/#/R-HSA-622382 PIP2 hydrolysis IEA Homo sapiens 58456 R-HSA-6802910 https://reactome.org/PathwayBrowser/#/R-HSA-6802910 Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants TAS Homo sapiens 58456 R-HSA-6802911 https://reactome.org/PathwayBrowser/#/R-HSA-6802911 High kinase activity BRAF complexes phosphorylate MAP2Ks TAS Homo sapiens 58456 R-HSA-6802912 https://reactome.org/PathwayBrowser/#/R-HSA-6802912 High kinase activity BRAF mutants bind MAP2Ks and MAPKs TAS Homo sapiens 58456 R-HSA-6802914 https://reactome.org/PathwayBrowser/#/R-HSA-6802914 RAS:GTP:moderate kinase activity p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 58456 R-HSA-6802918 https://reactome.org/PathwayBrowser/#/R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants TAS Homo sapiens 58456 R-HSA-6802919 https://reactome.org/PathwayBrowser/#/R-HSA-6802919 RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 58456 R-HSA-6802921 https://reactome.org/PathwayBrowser/#/R-HSA-6802921 Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants TAS Homo sapiens 58456 R-HSA-6802922 https://reactome.org/PathwayBrowser/#/R-HSA-6802922 Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS TAS Homo sapiens 58456 R-HSA-6802925 https://reactome.org/PathwayBrowser/#/R-HSA-6802925 Mutant RAS:p-RAF complexes bind MAP2Ks and MAPKs TAS Homo sapiens 58456 R-HSA-6802926 https://reactome.org/PathwayBrowser/#/R-HSA-6802926 Mutant RAS:p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 58456 R-HSA-6802932 https://reactome.org/PathwayBrowser/#/R-HSA-6802932 Dissociation of BRAF/RAF fusion complex TAS Homo sapiens 58456 R-HSA-6802933 https://reactome.org/PathwayBrowser/#/R-HSA-6802933 p-BRAF and RAF fusion dimers phosphorylate MAP2Ks TAS Homo sapiens 58456 R-HSA-6802934 https://reactome.org/PathwayBrowser/#/R-HSA-6802934 p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs TAS Homo sapiens 58456 R-HSA-6802935 https://reactome.org/PathwayBrowser/#/R-HSA-6802935 MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers TAS Homo sapiens 58456 R-HSA-6802942 https://reactome.org/PathwayBrowser/#/R-HSA-6802942 RAS:GTP:p-RAF complexes paradoxically bind MAP2Ks and MAPKs TAS Homo sapiens 58456 R-HSA-6802943 https://reactome.org/PathwayBrowser/#/R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 58456 R-HSA-6803227 https://reactome.org/PathwayBrowser/#/R-HSA-6803227 Dissociation of high activity BRAF complexes TAS Homo sapiens 58456 R-HSA-6803230 https://reactome.org/PathwayBrowser/#/R-HSA-6803230 Dissociation of moderate activity BRAF complexes TAS Homo sapiens 58456 R-HSA-6803233 https://reactome.org/PathwayBrowser/#/R-HSA-6803233 Dissociation of oncogenic RAS:RAF complex TAS Homo sapiens 58456 R-HSA-6803234 https://reactome.org/PathwayBrowser/#/R-HSA-6803234 Dissociation of paradoxically activated RAS:BRAF complexes TAS Homo sapiens 58456 R-HSA-6805981 https://reactome.org/PathwayBrowser/#/R-HSA-6805981 HMGB1 release from cells TAS Homo sapiens 58456 R-HSA-6810410 https://reactome.org/PathwayBrowser/#/R-HSA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus TAS Homo sapiens 58456 R-HSA-6811522 https://reactome.org/PathwayBrowser/#/R-HSA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus TAS Homo sapiens 58456 R-HSA-8849969 https://reactome.org/PathwayBrowser/#/R-HSA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane TAS Homo sapiens 58456 R-HSA-8852019 https://reactome.org/PathwayBrowser/#/R-HSA-8852019 MET bound PI3K generates PIP3 TAS Homo sapiens 58456 R-HSA-8856808 https://reactome.org/PathwayBrowser/#/R-HSA-8856808 Recruitment of AP-2 complex and clathrin TAS Homo sapiens 58456 R-HSA-8856813 https://reactome.org/PathwayBrowser/#/R-HSA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 TAS Homo sapiens 58456 R-HSA-8862280 https://reactome.org/PathwayBrowser/#/R-HSA-8862280 FCHo proteins bind nascent clathrin-coated pit TAS Homo sapiens 58456 R-HSA-8863895 https://reactome.org/PathwayBrowser/#/R-HSA-8863895 IKKB phosphorylates SNAP23 TAS Homo sapiens 58456 R-HSA-8866283 https://reactome.org/PathwayBrowser/#/R-HSA-8866283 ARBB recruits GPCRs into clathrin-coated pits TAS Homo sapiens 58456 R-HSA-8867041 https://reactome.org/PathwayBrowser/#/R-HSA-8867041 EGFR phosphorylates EPS15 TAS Homo sapiens 58456 R-HSA-8867044 https://reactome.org/PathwayBrowser/#/R-HSA-8867044 EGFR binds EPS15, EPN1, EPS15L1 TAS Homo sapiens 58456 R-HSA-8867047 https://reactome.org/PathwayBrowser/#/R-HSA-8867047 PTPN3 dephosphorylates EPS15 TAS Homo sapiens 58456 R-HSA-8867754 https://reactome.org/PathwayBrowser/#/R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit TAS Homo sapiens 58456 R-HSA-8867756 https://reactome.org/PathwayBrowser/#/R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit TAS Homo sapiens 58456 R-HSA-8868066 https://reactome.org/PathwayBrowser/#/R-HSA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 TAS Homo sapiens 58456 R-HSA-8868071 https://reactome.org/PathwayBrowser/#/R-HSA-8868071 Clathrin recruits PIK3C2A TAS Homo sapiens 58456 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 58456 R-HSA-8868230 https://reactome.org/PathwayBrowser/#/R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery TAS Homo sapiens 58456 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 58456 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 58456 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 58456 R-HSA-8871196 https://reactome.org/PathwayBrowser/#/R-HSA-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 TAS Homo sapiens 58456 R-HSA-8874470 https://reactome.org/PathwayBrowser/#/R-HSA-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane TAS Homo sapiens 58456 R-HSA-9021627 https://reactome.org/PathwayBrowser/#/R-HSA-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-9028519 https://reactome.org/PathwayBrowser/#/R-HSA-9028519 NTRK2-activated PI3K generates PIP3 IEA Homo sapiens 58456 R-HSA-9032478 https://reactome.org/PathwayBrowser/#/R-HSA-9032478 EPOR-associated PLCG hydrolyzes 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate IEA Homo sapiens 58456 R-HSA-937022 https://reactome.org/PathwayBrowser/#/R-HSA-937022 IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP TAS Homo sapiens 58456 R-HSA-937059 https://reactome.org/PathwayBrowser/#/R-HSA-937059 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex TAS Homo sapiens 58456 R-HSA-937079 https://reactome.org/PathwayBrowser/#/R-HSA-937079 MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 TAS Homo sapiens 58456 R-HSA-9603445 https://reactome.org/PathwayBrowser/#/R-HSA-9603445 Activated NTRK3 stimulates PI3K activity IEA Homo sapiens 58456 R-HSA-9647619 https://reactome.org/PathwayBrowser/#/R-HSA-9647619 GSDMD forms ring‐shaped oligomers TAS Homo sapiens 58456 R-HSA-9647631 https://reactome.org/PathwayBrowser/#/R-HSA-9647631 GSDMD (1-275) binds PIPs TAS Homo sapiens 58456 R-HSA-9647645 https://reactome.org/PathwayBrowser/#/R-HSA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures TAS Homo sapiens 58456 R-HSA-9647660 https://reactome.org/PathwayBrowser/#/R-HSA-9647660 GSDME (1-270) binds PIPs TAS Homo sapiens 58456 R-HSA-9656209 https://reactome.org/PathwayBrowser/#/R-HSA-9656209 Dissociation of RAS:RAF1 mutant complex TAS Homo sapiens 58456 R-HSA-9656211 https://reactome.org/PathwayBrowser/#/R-HSA-9656211 MAP2Ks and MAPKs bind to the activated mutant RAF1 complex TAS Homo sapiens 58456 R-HSA-9656214 https://reactome.org/PathwayBrowser/#/R-HSA-9656214 MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants TAS Homo sapiens 58456 R-HSA-9656215 https://reactome.org/PathwayBrowser/#/R-HSA-9656215 RAF1 mutant complexes phosphorylate MAP2K dimer TAS Homo sapiens 58456 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 58456 R-HSA-9657603 https://reactome.org/PathwayBrowser/#/R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs TAS Homo sapiens 58456 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 58456 R-HSA-9657608 https://reactome.org/PathwayBrowser/#/R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK TAS Homo sapiens 58456 R-HSA-9664664 https://reactome.org/PathwayBrowser/#/R-HSA-9664664 PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 converts PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-9664940 https://reactome.org/PathwayBrowser/#/R-HSA-9664940 PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR converts PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-9665407 https://reactome.org/PathwayBrowser/#/R-HSA-9665407 PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3 TAS Homo sapiens 58456 R-HSA-9670155 https://reactome.org/PathwayBrowser/#/R-HSA-9670155 CDC42:GTP binds PtdIns(4,5)P2:WASP,N-WASP IEA Homo sapiens 58456 R-HSA-9670156 https://reactome.org/PathwayBrowser/#/R-HSA-9670156 PtdIns(4,5)P2 binds WASP, N-WASP IEA Homo sapiens 58456 R-HSA-9670433 https://reactome.org/PathwayBrowser/#/R-HSA-9670433 KIT mutants:PI3K catalyze synthesis of PIP3 TAS Homo sapiens 58456 R-HSA-9672162 https://reactome.org/PathwayBrowser/#/R-HSA-9672162 PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of PDGFRA extracellular domain dimers TAS Homo sapiens 58456 R-HSA-9672177 https://reactome.org/PathwayBrowser/#/R-HSA-9672177 PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of mutant PDGFR TAS Homo sapiens 58456 R-HSA-9680389 https://reactome.org/PathwayBrowser/#/R-HSA-9680389 CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2 IEA Homo sapiens 58456 R-HSA-9710254 https://reactome.org/PathwayBrowser/#/R-HSA-9710254 GSDME oligomerizes TAS Homo sapiens 58456 R-HSA-9710468 https://reactome.org/PathwayBrowser/#/R-HSA-9710468 GSDME variant does not bind PIPs TAS Homo sapiens 58456 R-HSA-9712084 https://reactome.org/PathwayBrowser/#/R-HSA-9712084 PI3K synthesizes PIP3 downstream of ALK mutants TAS Homo sapiens 58456 R-HSA-9717205 https://reactome.org/PathwayBrowser/#/R-HSA-9717205 GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG IEA Homo sapiens 58456 R-MMU-109699 https://reactome.org/PathwayBrowser/#/R-MMU-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus 58456 R-MMU-111879 https://reactome.org/PathwayBrowser/#/R-MMU-111879 PIP2 hydrolysis IEA Mus musculus 58456 R-MMU-114688 https://reactome.org/PathwayBrowser/#/R-MMU-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Mus musculus 58456 R-MMU-114689 https://reactome.org/PathwayBrowser/#/R-MMU-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Mus musculus 58456 R-MMU-1250370 https://reactome.org/PathwayBrowser/#/R-MMU-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Mus musculus 58456 R-MMU-1250462 https://reactome.org/PathwayBrowser/#/R-MMU-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Mus musculus 58456 R-MMU-1306957 https://reactome.org/PathwayBrowser/#/R-MMU-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Mus musculus 58456 R-MMU-1306979 https://reactome.org/PathwayBrowser/#/R-MMU-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Mus musculus 58456 R-MMU-1433514 https://reactome.org/PathwayBrowser/#/R-MMU-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Mus musculus 58456 R-MMU-1675776 https://reactome.org/PathwayBrowser/#/R-MMU-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Mus musculus 58456 R-MMU-1675824 https://reactome.org/PathwayBrowser/#/R-MMU-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Mus musculus 58456 R-MMU-1676048 https://reactome.org/PathwayBrowser/#/R-MMU-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Mus musculus 58456 R-MMU-1676082 https://reactome.org/PathwayBrowser/#/R-MMU-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Mus musculus 58456 R-MMU-1676177 https://reactome.org/PathwayBrowser/#/R-MMU-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Mus musculus 58456 R-MMU-177939 https://reactome.org/PathwayBrowser/#/R-MMU-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Mus musculus 58456 R-MMU-1855177 https://reactome.org/PathwayBrowser/#/R-MMU-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Mus musculus 58456 R-MMU-1855214 https://reactome.org/PathwayBrowser/#/R-MMU-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Mus musculus 58456 R-MMU-1855221 https://reactome.org/PathwayBrowser/#/R-MMU-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Mus musculus 58456 R-MMU-186800 https://reactome.org/PathwayBrowser/#/R-MMU-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-198266 https://reactome.org/PathwayBrowser/#/R-MMU-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Mus musculus 58456 R-MMU-199456 https://reactome.org/PathwayBrowser/#/R-MMU-199456 PTEN dephosphorylates PIP3 IEA Mus musculus 58456 R-MMU-201510 https://reactome.org/PathwayBrowser/#/R-MMU-201510 PI3K synthesizes PIP3 downstream of ALK IEA Mus musculus 58456 R-MMU-202354 https://reactome.org/PathwayBrowser/#/R-MMU-202354 Translocation of PLC-gamma1 to PIP2 IEA Mus musculus 58456 R-MMU-202365 https://reactome.org/PathwayBrowser/#/R-MMU-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-202407 https://reactome.org/PathwayBrowser/#/R-MMU-202407 PLC-gamma1 hydrolyses PIP2 IEA Mus musculus 58456 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-2029466 https://reactome.org/PathwayBrowser/#/R-MMU-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Mus musculus 58456 R-MMU-2045911 https://reactome.org/PathwayBrowser/#/R-MMU-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Mus musculus 58456 R-MMU-2076220 https://reactome.org/PathwayBrowser/#/R-MMU-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Mus musculus 58456 R-MMU-2197690 https://reactome.org/PathwayBrowser/#/R-MMU-2197690 Detachment of WASP/WAVE IEA Mus musculus 58456 R-MMU-2197698 https://reactome.org/PathwayBrowser/#/R-MMU-2197698 Src phosphorylate WASP,N-WASP IEA Mus musculus 58456 R-MMU-2219524 https://reactome.org/PathwayBrowser/#/R-MMU-2219524 PDPK1 binds PIP2 IEA Mus musculus 58456 R-MMU-2316434 https://reactome.org/PathwayBrowser/#/R-MMU-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-2424480 https://reactome.org/PathwayBrowser/#/R-MMU-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-2559456 https://reactome.org/PathwayBrowser/#/R-MMU-2559456 TIRAP binds PIP2-rich regions in the plasma membrane IEA Mus musculus 58456 R-MMU-2730847 https://reactome.org/PathwayBrowser/#/R-MMU-2730847 Hydrolysis of PIP2 by PLCG IEA Mus musculus 58456 R-MMU-2730870 https://reactome.org/PathwayBrowser/#/R-MMU-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Mus musculus 58456 R-MMU-2750187 https://reactome.org/PathwayBrowser/#/R-MMU-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Mus musculus 58456 R-MMU-354060 https://reactome.org/PathwayBrowser/#/R-MMU-354060 Translocation of RIAM to plasma membrane IEA Mus musculus 58456 R-MMU-354066 https://reactome.org/PathwayBrowser/#/R-MMU-354066 Translocation of PTK2 to Focal complexes IEA Mus musculus 58456 R-MMU-354073 https://reactome.org/PathwayBrowser/#/R-MMU-354073 Autophosphorylation of PTK2 at Y397 IEA Mus musculus 58456 R-MMU-354077 https://reactome.org/PathwayBrowser/#/R-MMU-354077 Integrin alphaIIb beta3 activation IEA Mus musculus 58456 R-MMU-354087 https://reactome.org/PathwayBrowser/#/R-MMU-354087 Recruitment of GRB2 to p-PTK2 IEA Mus musculus 58456 R-MMU-354097 https://reactome.org/PathwayBrowser/#/R-MMU-354097 Activation of Talin IEA Mus musculus 58456 R-MMU-354124 https://reactome.org/PathwayBrowser/#/R-MMU-354124 Phosphorylation of pPTK2 by SRC IEA Mus musculus 58456 R-MMU-354149 https://reactome.org/PathwayBrowser/#/R-MMU-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Mus musculus 58456 R-MMU-354165 https://reactome.org/PathwayBrowser/#/R-MMU-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Mus musculus 58456 R-MMU-372693 https://reactome.org/PathwayBrowser/#/R-MMU-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Mus musculus 58456 R-MMU-372697 https://reactome.org/PathwayBrowser/#/R-MMU-372697 Crk binding to p130cas IEA Mus musculus 58456 R-MMU-372705 https://reactome.org/PathwayBrowser/#/R-MMU-372705 Recruitment of BCAR1 to PTK2 complex IEA Mus musculus 58456 R-MMU-374662 https://reactome.org/PathwayBrowser/#/R-MMU-374662 Translocation of Ezrin to plasma membrane IEA Mus musculus 58456 R-MMU-374663 https://reactome.org/PathwayBrowser/#/R-MMU-374663 DCC interaction with Ezrin IEA Mus musculus 58456 R-MMU-374664 https://reactome.org/PathwayBrowser/#/R-MMU-374664 Phosphorylation and activation of Ezrin IEA Mus musculus 58456 R-MMU-374680 https://reactome.org/PathwayBrowser/#/R-MMU-374680 L1 trans-homophilic interaction IEA Mus musculus 58456 R-MMU-3772436 https://reactome.org/PathwayBrowser/#/R-MMU-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Mus musculus 58456 R-MMU-377640 https://reactome.org/PathwayBrowser/#/R-MMU-377640 Autophosphorylation of SRC IEA Mus musculus 58456 R-MMU-377641 https://reactome.org/PathwayBrowser/#/R-MMU-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Mus musculus 58456 R-MMU-377643 https://reactome.org/PathwayBrowser/#/R-MMU-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Mus musculus 58456 R-MMU-377644 https://reactome.org/PathwayBrowser/#/R-MMU-377644 Release of CSK from SRC IEA Mus musculus 58456 R-MMU-389158 https://reactome.org/PathwayBrowser/#/R-MMU-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-392300 https://reactome.org/PathwayBrowser/#/R-MMU-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-3928595 https://reactome.org/PathwayBrowser/#/R-MMU-3928595 N-WASP binds ARP2/3 and G-actin IEA Mus musculus 58456 R-MMU-3928601 https://reactome.org/PathwayBrowser/#/R-MMU-3928601 CDC42 and PIP2 bind WASL, activating it IEA Mus musculus 58456 R-MMU-398193 https://reactome.org/PathwayBrowser/#/R-MMU-398193 PLC beta-mediated PIP2 hydrolysis IEA Mus musculus 58456 R-MMU-399998 https://reactome.org/PathwayBrowser/#/R-MMU-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Mus musculus 58456 R-MMU-429415 https://reactome.org/PathwayBrowser/#/R-MMU-429415 SYK binds to integrin alphaIIb beta3 IEA Mus musculus 58456 R-MMU-429441 https://reactome.org/PathwayBrowser/#/R-MMU-429441 SYK activation by SRC IEA Mus musculus 58456 R-MMU-432096 https://reactome.org/PathwayBrowser/#/R-MMU-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Mus musculus 58456 R-MMU-434634 https://reactome.org/PathwayBrowser/#/R-MMU-434634 PIP2 inhibits Vav1 TAS Mus musculus 58456 R-MMU-437162 https://reactome.org/PathwayBrowser/#/R-MMU-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-442273 https://reactome.org/PathwayBrowser/#/R-MMU-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Mus musculus 58456 R-MMU-442572 https://reactome.org/PathwayBrowser/#/R-MMU-442572 Activation of WASP and N-WASP by CDC42 TAS Mus musculus 58456 R-MMU-443779 https://reactome.org/PathwayBrowser/#/R-MMU-443779 Linkage of L1 with treadmilling F-actin IEA Mus musculus 58456 R-MMU-443905 https://reactome.org/PathwayBrowser/#/R-MMU-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Mus musculus 58456 R-MMU-443910 https://reactome.org/PathwayBrowser/#/R-MMU-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Mus musculus 58456 R-MMU-449058 https://reactome.org/PathwayBrowser/#/R-MMU-449058 Interleukin-1 family are secreted IEA Mus musculus 58456 R-MMU-5218819 https://reactome.org/PathwayBrowser/#/R-MMU-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-5607735 https://reactome.org/PathwayBrowser/#/R-MMU-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Mus musculus 58456 R-MMU-5620975 https://reactome.org/PathwayBrowser/#/R-MMU-5620975 MLKL binds PIPs IEA Mus musculus 58456 R-MMU-5654690 https://reactome.org/PathwayBrowser/#/R-MMU-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-5654692 https://reactome.org/PathwayBrowser/#/R-MMU-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-5654697 https://reactome.org/PathwayBrowser/#/R-MMU-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-5654701 https://reactome.org/PathwayBrowser/#/R-MMU-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-5654705 https://reactome.org/PathwayBrowser/#/R-MMU-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-5654709 https://reactome.org/PathwayBrowser/#/R-MMU-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-5654714 https://reactome.org/PathwayBrowser/#/R-MMU-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-5654717 https://reactome.org/PathwayBrowser/#/R-MMU-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-5672972 https://reactome.org/PathwayBrowser/#/R-MMU-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Mus musculus 58456 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 58456 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 58456 R-MMU-5672980 https://reactome.org/PathwayBrowser/#/R-MMU-5672980 Dissociation of RAS:RAF complex IEA Mus musculus 58456 R-MMU-6805981 https://reactome.org/PathwayBrowser/#/R-MMU-6805981 HMGB1 release from cells IEA Mus musculus 58456 R-MMU-6810410 https://reactome.org/PathwayBrowser/#/R-MMU-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Mus musculus 58456 R-MMU-6811522 https://reactome.org/PathwayBrowser/#/R-MMU-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Mus musculus 58456 R-MMU-8849969 https://reactome.org/PathwayBrowser/#/R-MMU-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Mus musculus 58456 R-MMU-8852019 https://reactome.org/PathwayBrowser/#/R-MMU-8852019 MET bound PI3K generates PIP3 IEA Mus musculus 58456 R-MMU-8856808 https://reactome.org/PathwayBrowser/#/R-MMU-8856808 Recruitment of AP-2 complex and clathrin IEA Mus musculus 58456 R-MMU-8856813 https://reactome.org/PathwayBrowser/#/R-MMU-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Mus musculus 58456 R-MMU-8866283 https://reactome.org/PathwayBrowser/#/R-MMU-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Mus musculus 58456 R-MMU-8867041 https://reactome.org/PathwayBrowser/#/R-MMU-8867041 EGFR phosphorylates EPS15 IEA Mus musculus 58456 R-MMU-8867044 https://reactome.org/PathwayBrowser/#/R-MMU-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Mus musculus 58456 R-MMU-8867047 https://reactome.org/PathwayBrowser/#/R-MMU-8867047 PTPN3 dephosphorylates EPS15 IEA Mus musculus 58456 R-MMU-8867754 https://reactome.org/PathwayBrowser/#/R-MMU-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Mus musculus 58456 R-MMU-8867756 https://reactome.org/PathwayBrowser/#/R-MMU-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Mus musculus 58456 R-MMU-8868066 https://reactome.org/PathwayBrowser/#/R-MMU-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Mus musculus 58456 R-MMU-8868071 https://reactome.org/PathwayBrowser/#/R-MMU-8868071 Clathrin recruits PIK3C2A IEA Mus musculus 58456 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 58456 R-MMU-8868236 https://reactome.org/PathwayBrowser/#/R-MMU-8868236 BAR domain proteins recruit dynamin IEA Mus musculus 58456 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 58456 R-MMU-8868651 https://reactome.org/PathwayBrowser/#/R-MMU-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Mus musculus 58456 R-MMU-8871196 https://reactome.org/PathwayBrowser/#/R-MMU-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Mus musculus 58456 R-MMU-8874470 https://reactome.org/PathwayBrowser/#/R-MMU-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Mus musculus 58456 R-MMU-9021627 https://reactome.org/PathwayBrowser/#/R-MMU-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus 58456 R-MMU-9031553 https://reactome.org/PathwayBrowser/#/R-MMU-9031553 Activated Ntrk2 activates PI3K signaling TAS Mus musculus 58456 R-MMU-9032476 https://reactome.org/PathwayBrowser/#/R-MMU-9032476 Epor-associated Plcg hydrolyzes 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate TAS Mus musculus 58456 R-MMU-9647619 https://reactome.org/PathwayBrowser/#/R-MMU-9647619 GSDMD forms ring‐shaped oligomers IEA Mus musculus 58456 R-MMU-9647631 https://reactome.org/PathwayBrowser/#/R-MMU-9647631 GSDMD (1-275) binds PIPs IEA Mus musculus 58456 R-MMU-9647645 https://reactome.org/PathwayBrowser/#/R-MMU-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Mus musculus 58456 R-MMU-9647660 https://reactome.org/PathwayBrowser/#/R-MMU-9647660 GSDME (1-270) binds PIPs IEA Mus musculus 58456 R-MMU-9657599 https://reactome.org/PathwayBrowser/#/R-MMU-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Mus musculus 58456 R-MMU-9657603 https://reactome.org/PathwayBrowser/#/R-MMU-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Mus musculus 58456 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 58456 R-MMU-9657608 https://reactome.org/PathwayBrowser/#/R-MMU-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Mus musculus 58456 R-MMU-9682182 https://reactome.org/PathwayBrowser/#/R-MMU-9682182 Csf1r-associated PI3K phosphorylates phosphatidylinositol 4,5-bisphosphate TAS Mus musculus 58456 R-MMU-9710254 https://reactome.org/PathwayBrowser/#/R-MMU-9710254 GSDME oligomerizes IEA Mus musculus 58456 R-NUL-443049 https://reactome.org/PathwayBrowser/#/R-NUL-443049 L1 dimer binds Ankyrin TAS Homo sapiens 58456 R-NUL-9616944 https://reactome.org/PathwayBrowser/#/R-NUL-9616944 Activated Ntrk3 stimulates PI3K activity TAS Mus musculus 58456 R-NUL-9620024 https://reactome.org/PathwayBrowser/#/R-NUL-9620024 PDPK1 phosphorylates Rps6ka2 TAS Homo sapiens 58456 R-NUL-9717576 https://reactome.org/PathwayBrowser/#/R-NUL-9717576 Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG TAS Bos taurus 58456 R-PFA-114689 https://reactome.org/PathwayBrowser/#/R-PFA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Plasmodium falciparum 58456 R-PFA-1675776 https://reactome.org/PathwayBrowser/#/R-PFA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Plasmodium falciparum 58456 R-PFA-1675824 https://reactome.org/PathwayBrowser/#/R-PFA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Plasmodium falciparum 58456 R-PFA-1676082 https://reactome.org/PathwayBrowser/#/R-PFA-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Plasmodium falciparum 58456 R-PFA-1676177 https://reactome.org/PathwayBrowser/#/R-PFA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Plasmodium falciparum 58456 R-PFA-1855177 https://reactome.org/PathwayBrowser/#/R-PFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Plasmodium falciparum 58456 R-PFA-1855214 https://reactome.org/PathwayBrowser/#/R-PFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Plasmodium falciparum 58456 R-PFA-1855221 https://reactome.org/PathwayBrowser/#/R-PFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Plasmodium falciparum 58456 R-PFA-202354 https://reactome.org/PathwayBrowser/#/R-PFA-202354 Translocation of PLC-gamma1 to PIP2 IEA Plasmodium falciparum 58456 R-PFA-202407 https://reactome.org/PathwayBrowser/#/R-PFA-202407 PLC-gamma1 hydrolyses PIP2 IEA Plasmodium falciparum 58456 R-PFA-2219524 https://reactome.org/PathwayBrowser/#/R-PFA-2219524 PDPK1 binds PIP2 IEA Plasmodium falciparum 58456 R-PFA-5607735 https://reactome.org/PathwayBrowser/#/R-PFA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Plasmodium falciparum 58456 R-PFA-6811522 https://reactome.org/PathwayBrowser/#/R-PFA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Plasmodium falciparum 58456 R-PFA-8849969 https://reactome.org/PathwayBrowser/#/R-PFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Plasmodium falciparum 58456 R-PFA-8868066 https://reactome.org/PathwayBrowser/#/R-PFA-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Plasmodium falciparum 58456 R-RNO-109699 https://reactome.org/PathwayBrowser/#/R-RNO-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus 58456 R-RNO-111879 https://reactome.org/PathwayBrowser/#/R-RNO-111879 PIP2 hydrolysis IEA Rattus norvegicus 58456 R-RNO-114688 https://reactome.org/PathwayBrowser/#/R-RNO-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Rattus norvegicus 58456 R-RNO-114689 https://reactome.org/PathwayBrowser/#/R-RNO-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Rattus norvegicus 58456 R-RNO-1250370 https://reactome.org/PathwayBrowser/#/R-RNO-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Rattus norvegicus 58456 R-RNO-1250462 https://reactome.org/PathwayBrowser/#/R-RNO-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Rattus norvegicus 58456 R-RNO-1306957 https://reactome.org/PathwayBrowser/#/R-RNO-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Rattus norvegicus 58456 R-RNO-1306979 https://reactome.org/PathwayBrowser/#/R-RNO-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Rattus norvegicus 58456 R-RNO-1433514 https://reactome.org/PathwayBrowser/#/R-RNO-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Rattus norvegicus 58456 R-RNO-1675776 https://reactome.org/PathwayBrowser/#/R-RNO-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Rattus norvegicus 58456 R-RNO-1675824 https://reactome.org/PathwayBrowser/#/R-RNO-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Rattus norvegicus 58456 R-RNO-1676048 https://reactome.org/PathwayBrowser/#/R-RNO-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Rattus norvegicus 58456 R-RNO-1676082 https://reactome.org/PathwayBrowser/#/R-RNO-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Rattus norvegicus 58456 R-RNO-1676177 https://reactome.org/PathwayBrowser/#/R-RNO-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Rattus norvegicus 58456 R-RNO-177939 https://reactome.org/PathwayBrowser/#/R-RNO-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Rattus norvegicus 58456 R-RNO-182061 https://reactome.org/PathwayBrowser/#/R-RNO-182061 Active Plcg1 hydrolyses PIP2 TAS Rattus norvegicus 58456 R-RNO-1855177 https://reactome.org/PathwayBrowser/#/R-RNO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Rattus norvegicus 58456 R-RNO-1855214 https://reactome.org/PathwayBrowser/#/R-RNO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Rattus norvegicus 58456 R-RNO-1855221 https://reactome.org/PathwayBrowser/#/R-RNO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Rattus norvegicus 58456 R-RNO-186800 https://reactome.org/PathwayBrowser/#/R-RNO-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-198266 https://reactome.org/PathwayBrowser/#/R-RNO-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Rattus norvegicus 58456 R-RNO-199456 https://reactome.org/PathwayBrowser/#/R-RNO-199456 PTEN dephosphorylates PIP3 IEA Rattus norvegicus 58456 R-RNO-201510 https://reactome.org/PathwayBrowser/#/R-RNO-201510 PI3K synthesizes PIP3 downstream of ALK IEA Rattus norvegicus 58456 R-RNO-202354 https://reactome.org/PathwayBrowser/#/R-RNO-202354 Translocation of PLC-gamma1 to PIP2 IEA Rattus norvegicus 58456 R-RNO-202365 https://reactome.org/PathwayBrowser/#/R-RNO-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-202407 https://reactome.org/PathwayBrowser/#/R-RNO-202407 PLC-gamma1 hydrolyses PIP2 IEA Rattus norvegicus 58456 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-2029466 https://reactome.org/PathwayBrowser/#/R-RNO-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Rattus norvegicus 58456 R-RNO-2045911 https://reactome.org/PathwayBrowser/#/R-RNO-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Rattus norvegicus 58456 R-RNO-2076220 https://reactome.org/PathwayBrowser/#/R-RNO-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Rattus norvegicus 58456 R-RNO-2197690 https://reactome.org/PathwayBrowser/#/R-RNO-2197690 Detachment of WASP/WAVE IEA Rattus norvegicus 58456 R-RNO-2197698 https://reactome.org/PathwayBrowser/#/R-RNO-2197698 Src phosphorylate WASP,N-WASP IEA Rattus norvegicus 58456 R-RNO-2219524 https://reactome.org/PathwayBrowser/#/R-RNO-2219524 PDPK1 binds PIP2 IEA Rattus norvegicus 58456 R-RNO-2316434 https://reactome.org/PathwayBrowser/#/R-RNO-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-2424480 https://reactome.org/PathwayBrowser/#/R-RNO-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-2559456 https://reactome.org/PathwayBrowser/#/R-RNO-2559456 TIRAP binds PIP2-rich regions in the plasma membrane IEA Rattus norvegicus 58456 R-RNO-2730847 https://reactome.org/PathwayBrowser/#/R-RNO-2730847 Hydrolysis of PIP2 by PLCG IEA Rattus norvegicus 58456 R-RNO-2730870 https://reactome.org/PathwayBrowser/#/R-RNO-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Rattus norvegicus 58456 R-RNO-2750187 https://reactome.org/PathwayBrowser/#/R-RNO-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Rattus norvegicus 58456 R-RNO-354060 https://reactome.org/PathwayBrowser/#/R-RNO-354060 Translocation of RIAM to plasma membrane IEA Rattus norvegicus 58456 R-RNO-354066 https://reactome.org/PathwayBrowser/#/R-RNO-354066 Translocation of PTK2 to Focal complexes IEA Rattus norvegicus 58456 R-RNO-354073 https://reactome.org/PathwayBrowser/#/R-RNO-354073 Autophosphorylation of PTK2 at Y397 IEA Rattus norvegicus 58456 R-RNO-354077 https://reactome.org/PathwayBrowser/#/R-RNO-354077 Integrin alphaIIb beta3 activation IEA Rattus norvegicus 58456 R-RNO-354087 https://reactome.org/PathwayBrowser/#/R-RNO-354087 Recruitment of GRB2 to p-PTK2 IEA Rattus norvegicus 58456 R-RNO-354097 https://reactome.org/PathwayBrowser/#/R-RNO-354097 Activation of Talin IEA Rattus norvegicus 58456 R-RNO-354124 https://reactome.org/PathwayBrowser/#/R-RNO-354124 Phosphorylation of pPTK2 by SRC IEA Rattus norvegicus 58456 R-RNO-354149 https://reactome.org/PathwayBrowser/#/R-RNO-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Rattus norvegicus 58456 R-RNO-354165 https://reactome.org/PathwayBrowser/#/R-RNO-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Rattus norvegicus 58456 R-RNO-372693 https://reactome.org/PathwayBrowser/#/R-RNO-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Rattus norvegicus 58456 R-RNO-372697 https://reactome.org/PathwayBrowser/#/R-RNO-372697 Crk binding to p130cas IEA Rattus norvegicus 58456 R-RNO-372705 https://reactome.org/PathwayBrowser/#/R-RNO-372705 Recruitment of BCAR1 to PTK2 complex IEA Rattus norvegicus 58456 R-RNO-374662 https://reactome.org/PathwayBrowser/#/R-RNO-374662 Translocation of Ezrin to plasma membrane IEA Rattus norvegicus 58456 R-RNO-374663 https://reactome.org/PathwayBrowser/#/R-RNO-374663 DCC interaction with Ezrin IEA Rattus norvegicus 58456 R-RNO-374664 https://reactome.org/PathwayBrowser/#/R-RNO-374664 Phosphorylation and activation of Ezrin IEA Rattus norvegicus 58456 R-RNO-374680 https://reactome.org/PathwayBrowser/#/R-RNO-374680 L1 trans-homophilic interaction IEA Rattus norvegicus 58456 R-RNO-3772436 https://reactome.org/PathwayBrowser/#/R-RNO-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Rattus norvegicus 58456 R-RNO-377640 https://reactome.org/PathwayBrowser/#/R-RNO-377640 Autophosphorylation of SRC IEA Rattus norvegicus 58456 R-RNO-377641 https://reactome.org/PathwayBrowser/#/R-RNO-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Rattus norvegicus 58456 R-RNO-377643 https://reactome.org/PathwayBrowser/#/R-RNO-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Rattus norvegicus 58456 R-RNO-377644 https://reactome.org/PathwayBrowser/#/R-RNO-377644 Release of CSK from SRC IEA Rattus norvegicus 58456 R-RNO-389158 https://reactome.org/PathwayBrowser/#/R-RNO-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-392300 https://reactome.org/PathwayBrowser/#/R-RNO-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-3928595 https://reactome.org/PathwayBrowser/#/R-RNO-3928595 N-WASP binds ARP2/3 and G-actin IEA Rattus norvegicus 58456 R-RNO-3928601 https://reactome.org/PathwayBrowser/#/R-RNO-3928601 CDC42 and PIP2 bind WASL, activating it IEA Rattus norvegicus 58456 R-RNO-399998 https://reactome.org/PathwayBrowser/#/R-RNO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Rattus norvegicus 58456 R-RNO-429415 https://reactome.org/PathwayBrowser/#/R-RNO-429415 SYK binds to integrin alphaIIb beta3 IEA Rattus norvegicus 58456 R-RNO-429441 https://reactome.org/PathwayBrowser/#/R-RNO-429441 SYK activation by SRC IEA Rattus norvegicus 58456 R-RNO-432096 https://reactome.org/PathwayBrowser/#/R-RNO-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Rattus norvegicus 58456 R-RNO-437162 https://reactome.org/PathwayBrowser/#/R-RNO-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-442273 https://reactome.org/PathwayBrowser/#/R-RNO-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Rattus norvegicus 58456 R-RNO-443768 https://reactome.org/PathwayBrowser/#/R-RNO-443768 L1 binds ERM family members TAS Rattus norvegicus 58456 R-RNO-443779 https://reactome.org/PathwayBrowser/#/R-RNO-443779 Linkage of L1 with treadmilling F-actin IEA Rattus norvegicus 58456 R-RNO-443905 https://reactome.org/PathwayBrowser/#/R-RNO-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Rattus norvegicus 58456 R-RNO-443910 https://reactome.org/PathwayBrowser/#/R-RNO-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Rattus norvegicus 58456 R-RNO-449058 https://reactome.org/PathwayBrowser/#/R-RNO-449058 Interleukin-1 family are secreted IEA Rattus norvegicus 58456 R-RNO-5218819 https://reactome.org/PathwayBrowser/#/R-RNO-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-5607735 https://reactome.org/PathwayBrowser/#/R-RNO-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Rattus norvegicus 58456 R-RNO-5620975 https://reactome.org/PathwayBrowser/#/R-RNO-5620975 MLKL binds PIPs IEA Rattus norvegicus 58456 R-RNO-5654690 https://reactome.org/PathwayBrowser/#/R-RNO-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-5654692 https://reactome.org/PathwayBrowser/#/R-RNO-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-5654697 https://reactome.org/PathwayBrowser/#/R-RNO-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-5654701 https://reactome.org/PathwayBrowser/#/R-RNO-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-5654705 https://reactome.org/PathwayBrowser/#/R-RNO-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-5654709 https://reactome.org/PathwayBrowser/#/R-RNO-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-5654714 https://reactome.org/PathwayBrowser/#/R-RNO-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-5654717 https://reactome.org/PathwayBrowser/#/R-RNO-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-5672972 https://reactome.org/PathwayBrowser/#/R-RNO-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Rattus norvegicus 58456 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 58456 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 58456 R-RNO-5672980 https://reactome.org/PathwayBrowser/#/R-RNO-5672980 Dissociation of RAS:RAF complex IEA Rattus norvegicus 58456 R-RNO-622387 https://reactome.org/PathwayBrowser/#/R-RNO-622387 PIP2 hydrolysis TAS Rattus norvegicus 58456 R-RNO-6805981 https://reactome.org/PathwayBrowser/#/R-RNO-6805981 HMGB1 release from cells IEA Rattus norvegicus 58456 R-RNO-6810410 https://reactome.org/PathwayBrowser/#/R-RNO-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Rattus norvegicus 58456 R-RNO-6811522 https://reactome.org/PathwayBrowser/#/R-RNO-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Rattus norvegicus 58456 R-RNO-8849969 https://reactome.org/PathwayBrowser/#/R-RNO-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Rattus norvegicus 58456 R-RNO-8852019 https://reactome.org/PathwayBrowser/#/R-RNO-8852019 MET bound PI3K generates PIP3 IEA Rattus norvegicus 58456 R-RNO-8856808 https://reactome.org/PathwayBrowser/#/R-RNO-8856808 Recruitment of AP-2 complex and clathrin IEA Rattus norvegicus 58456 R-RNO-8856813 https://reactome.org/PathwayBrowser/#/R-RNO-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Rattus norvegicus 58456 R-RNO-8866283 https://reactome.org/PathwayBrowser/#/R-RNO-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Rattus norvegicus 58456 R-RNO-8867041 https://reactome.org/PathwayBrowser/#/R-RNO-8867041 EGFR phosphorylates EPS15 IEA Rattus norvegicus 58456 R-RNO-8867044 https://reactome.org/PathwayBrowser/#/R-RNO-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Rattus norvegicus 58456 R-RNO-8867047 https://reactome.org/PathwayBrowser/#/R-RNO-8867047 PTPN3 dephosphorylates EPS15 IEA Rattus norvegicus 58456 R-RNO-8867754 https://reactome.org/PathwayBrowser/#/R-RNO-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Rattus norvegicus 58456 R-RNO-8867756 https://reactome.org/PathwayBrowser/#/R-RNO-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Rattus norvegicus 58456 R-RNO-8868066 https://reactome.org/PathwayBrowser/#/R-RNO-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Rattus norvegicus 58456 R-RNO-8868071 https://reactome.org/PathwayBrowser/#/R-RNO-8868071 Clathrin recruits PIK3C2A IEA Rattus norvegicus 58456 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 58456 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus 58456 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 58456 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus 58456 R-RNO-8871196 https://reactome.org/PathwayBrowser/#/R-RNO-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Rattus norvegicus 58456 R-RNO-8874470 https://reactome.org/PathwayBrowser/#/R-RNO-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Rattus norvegicus 58456 R-RNO-9021627 https://reactome.org/PathwayBrowser/#/R-RNO-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus 58456 R-RNO-9647619 https://reactome.org/PathwayBrowser/#/R-RNO-9647619 GSDMD forms ring‐shaped oligomers IEA Rattus norvegicus 58456 R-RNO-9647631 https://reactome.org/PathwayBrowser/#/R-RNO-9647631 GSDMD (1-275) binds PIPs IEA Rattus norvegicus 58456 R-RNO-9647645 https://reactome.org/PathwayBrowser/#/R-RNO-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Rattus norvegicus 58456 R-RNO-9647660 https://reactome.org/PathwayBrowser/#/R-RNO-9647660 GSDME (1-270) binds PIPs IEA Rattus norvegicus 58456 R-RNO-9657599 https://reactome.org/PathwayBrowser/#/R-RNO-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Rattus norvegicus 58456 R-RNO-9657603 https://reactome.org/PathwayBrowser/#/R-RNO-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Rattus norvegicus 58456 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 58456 R-RNO-9657608 https://reactome.org/PathwayBrowser/#/R-RNO-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Rattus norvegicus 58456 R-RNO-9710254 https://reactome.org/PathwayBrowser/#/R-RNO-9710254 GSDME oligomerizes IEA Rattus norvegicus 58456 R-SCE-111879 https://reactome.org/PathwayBrowser/#/R-SCE-111879 PIP2 hydrolysis IEA Saccharomyces cerevisiae 58456 R-SCE-114688 https://reactome.org/PathwayBrowser/#/R-SCE-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Saccharomyces cerevisiae 58456 R-SCE-114689 https://reactome.org/PathwayBrowser/#/R-SCE-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Saccharomyces cerevisiae 58456 R-SCE-1675776 https://reactome.org/PathwayBrowser/#/R-SCE-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Saccharomyces cerevisiae 58456 R-SCE-1676082 https://reactome.org/PathwayBrowser/#/R-SCE-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Saccharomyces cerevisiae 58456 R-SCE-1676177 https://reactome.org/PathwayBrowser/#/R-SCE-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Saccharomyces cerevisiae 58456 R-SCE-1855177 https://reactome.org/PathwayBrowser/#/R-SCE-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Saccharomyces cerevisiae 58456 R-SCE-1855214 https://reactome.org/PathwayBrowser/#/R-SCE-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Saccharomyces cerevisiae 58456 R-SCE-1855221 https://reactome.org/PathwayBrowser/#/R-SCE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Saccharomyces cerevisiae 58456 R-SCE-199456 https://reactome.org/PathwayBrowser/#/R-SCE-199456 PTEN dephosphorylates PIP3 IEA Saccharomyces cerevisiae 58456 R-SCE-202354 https://reactome.org/PathwayBrowser/#/R-SCE-202354 Translocation of PLC-gamma1 to PIP2 IEA Saccharomyces cerevisiae 58456 R-SCE-202407 https://reactome.org/PathwayBrowser/#/R-SCE-202407 PLC-gamma1 hydrolyses PIP2 IEA Saccharomyces cerevisiae 58456 R-SCE-2219524 https://reactome.org/PathwayBrowser/#/R-SCE-2219524 PDPK1 binds PIP2 IEA Saccharomyces cerevisiae 58456 R-SCE-399998 https://reactome.org/PathwayBrowser/#/R-SCE-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Saccharomyces cerevisiae 58456 R-SCE-5607735 https://reactome.org/PathwayBrowser/#/R-SCE-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Saccharomyces cerevisiae 58456 R-SCE-6811522 https://reactome.org/PathwayBrowser/#/R-SCE-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Saccharomyces cerevisiae 58456 R-SCE-8856813 https://reactome.org/PathwayBrowser/#/R-SCE-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Saccharomyces cerevisiae 58456 R-SCE-8868066 https://reactome.org/PathwayBrowser/#/R-SCE-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Saccharomyces cerevisiae 58456 R-SCE-8871196 https://reactome.org/PathwayBrowser/#/R-SCE-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Saccharomyces cerevisiae 58456 R-SPO-111879 https://reactome.org/PathwayBrowser/#/R-SPO-111879 PIP2 hydrolysis IEA Schizosaccharomyces pombe 58456 R-SPO-114688 https://reactome.org/PathwayBrowser/#/R-SPO-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Schizosaccharomyces pombe 58456 R-SPO-114689 https://reactome.org/PathwayBrowser/#/R-SPO-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Schizosaccharomyces pombe 58456 R-SPO-1675776 https://reactome.org/PathwayBrowser/#/R-SPO-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Schizosaccharomyces pombe 58456 R-SPO-1675824 https://reactome.org/PathwayBrowser/#/R-SPO-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Schizosaccharomyces pombe 58456 R-SPO-1676082 https://reactome.org/PathwayBrowser/#/R-SPO-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Schizosaccharomyces pombe 58456 R-SPO-1676177 https://reactome.org/PathwayBrowser/#/R-SPO-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Schizosaccharomyces pombe 58456 R-SPO-1855177 https://reactome.org/PathwayBrowser/#/R-SPO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Schizosaccharomyces pombe 58456 R-SPO-1855214 https://reactome.org/PathwayBrowser/#/R-SPO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Schizosaccharomyces pombe 58456 R-SPO-1855221 https://reactome.org/PathwayBrowser/#/R-SPO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Schizosaccharomyces pombe 58456 R-SPO-199456 https://reactome.org/PathwayBrowser/#/R-SPO-199456 PTEN dephosphorylates PIP3 IEA Schizosaccharomyces pombe 58456 R-SPO-202354 https://reactome.org/PathwayBrowser/#/R-SPO-202354 Translocation of PLC-gamma1 to PIP2 IEA Schizosaccharomyces pombe 58456 R-SPO-202407 https://reactome.org/PathwayBrowser/#/R-SPO-202407 PLC-gamma1 hydrolyses PIP2 IEA Schizosaccharomyces pombe 58456 R-SPO-2219524 https://reactome.org/PathwayBrowser/#/R-SPO-2219524 PDPK1 binds PIP2 IEA Schizosaccharomyces pombe 58456 R-SPO-399998 https://reactome.org/PathwayBrowser/#/R-SPO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Schizosaccharomyces pombe 58456 R-SPO-5607735 https://reactome.org/PathwayBrowser/#/R-SPO-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Schizosaccharomyces pombe 58456 R-SPO-6811522 https://reactome.org/PathwayBrowser/#/R-SPO-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Schizosaccharomyces pombe 58456 R-SPO-8856813 https://reactome.org/PathwayBrowser/#/R-SPO-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Schizosaccharomyces pombe 58456 R-SPO-8868066 https://reactome.org/PathwayBrowser/#/R-SPO-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Schizosaccharomyces pombe 58456 R-SPO-8871196 https://reactome.org/PathwayBrowser/#/R-SPO-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Schizosaccharomyces pombe 58456 R-SSC-109699 https://reactome.org/PathwayBrowser/#/R-SSC-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa 58456 R-SSC-111879 https://reactome.org/PathwayBrowser/#/R-SSC-111879 PIP2 hydrolysis IEA Sus scrofa 58456 R-SSC-114688 https://reactome.org/PathwayBrowser/#/R-SSC-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Sus scrofa 58456 R-SSC-114689 https://reactome.org/PathwayBrowser/#/R-SSC-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Sus scrofa 58456 R-SSC-1250370 https://reactome.org/PathwayBrowser/#/R-SSC-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Sus scrofa 58456 R-SSC-1250462 https://reactome.org/PathwayBrowser/#/R-SSC-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Sus scrofa 58456 R-SSC-1306957 https://reactome.org/PathwayBrowser/#/R-SSC-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Sus scrofa 58456 R-SSC-1306979 https://reactome.org/PathwayBrowser/#/R-SSC-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Sus scrofa 58456 R-SSC-1433514 https://reactome.org/PathwayBrowser/#/R-SSC-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Sus scrofa 58456 R-SSC-1675776 https://reactome.org/PathwayBrowser/#/R-SSC-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Sus scrofa 58456 R-SSC-1675824 https://reactome.org/PathwayBrowser/#/R-SSC-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Sus scrofa 58456 R-SSC-1676048 https://reactome.org/PathwayBrowser/#/R-SSC-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Sus scrofa 58456 R-SSC-1676082 https://reactome.org/PathwayBrowser/#/R-SSC-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Sus scrofa 58456 R-SSC-1676177 https://reactome.org/PathwayBrowser/#/R-SSC-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Sus scrofa 58456 R-SSC-177939 https://reactome.org/PathwayBrowser/#/R-SSC-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Sus scrofa 58456 R-SSC-1855177 https://reactome.org/PathwayBrowser/#/R-SSC-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Sus scrofa 58456 R-SSC-1855214 https://reactome.org/PathwayBrowser/#/R-SSC-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Sus scrofa 58456 R-SSC-1855221 https://reactome.org/PathwayBrowser/#/R-SSC-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Sus scrofa 58456 R-SSC-186800 https://reactome.org/PathwayBrowser/#/R-SSC-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-198266 https://reactome.org/PathwayBrowser/#/R-SSC-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Sus scrofa 58456 R-SSC-199456 https://reactome.org/PathwayBrowser/#/R-SSC-199456 PTEN dephosphorylates PIP3 IEA Sus scrofa 58456 R-SSC-201510 https://reactome.org/PathwayBrowser/#/R-SSC-201510 PI3K synthesizes PIP3 downstream of ALK IEA Sus scrofa 58456 R-SSC-202354 https://reactome.org/PathwayBrowser/#/R-SSC-202354 Translocation of PLC-gamma1 to PIP2 IEA Sus scrofa 58456 R-SSC-202365 https://reactome.org/PathwayBrowser/#/R-SSC-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-202407 https://reactome.org/PathwayBrowser/#/R-SSC-202407 PLC-gamma1 hydrolyses PIP2 IEA Sus scrofa 58456 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa 58456 R-SSC-2045911 https://reactome.org/PathwayBrowser/#/R-SSC-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Sus scrofa 58456 R-SSC-2076220 https://reactome.org/PathwayBrowser/#/R-SSC-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Sus scrofa 58456 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa 58456 R-SSC-2197691 https://reactome.org/PathwayBrowser/#/R-SSC-2197691 WIP binds WASP,N-WASP, activating them IEA Sus scrofa 58456 R-SSC-2219524 https://reactome.org/PathwayBrowser/#/R-SSC-2219524 PDPK1 binds PIP2 IEA Sus scrofa 58456 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-2424480 https://reactome.org/PathwayBrowser/#/R-SSC-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-2559456 https://reactome.org/PathwayBrowser/#/R-SSC-2559456 TIRAP binds PIP2-rich regions in the plasma membrane IEA Sus scrofa 58456 R-SSC-2730847 https://reactome.org/PathwayBrowser/#/R-SSC-2730847 Hydrolysis of PIP2 by PLCG IEA Sus scrofa 58456 R-SSC-2730870 https://reactome.org/PathwayBrowser/#/R-SSC-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Sus scrofa 58456 R-SSC-2750187 https://reactome.org/PathwayBrowser/#/R-SSC-2750187 Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG IEA Sus scrofa 58456 R-SSC-354060 https://reactome.org/PathwayBrowser/#/R-SSC-354060 Translocation of RIAM to plasma membrane IEA Sus scrofa 58456 R-SSC-354073 https://reactome.org/PathwayBrowser/#/R-SSC-354073 Autophosphorylation of PTK2 at Y397 IEA Sus scrofa 58456 R-SSC-354077 https://reactome.org/PathwayBrowser/#/R-SSC-354077 Integrin alphaIIb beta3 activation IEA Sus scrofa 58456 R-SSC-354087 https://reactome.org/PathwayBrowser/#/R-SSC-354087 Recruitment of GRB2 to p-PTK2 IEA Sus scrofa 58456 R-SSC-354097 https://reactome.org/PathwayBrowser/#/R-SSC-354097 Activation of Talin IEA Sus scrofa 58456 R-SSC-354124 https://reactome.org/PathwayBrowser/#/R-SSC-354124 Phosphorylation of pPTK2 by SRC IEA Sus scrofa 58456 R-SSC-354149 https://reactome.org/PathwayBrowser/#/R-SSC-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Sus scrofa 58456 R-SSC-354165 https://reactome.org/PathwayBrowser/#/R-SSC-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Sus scrofa 58456 R-SSC-372693 https://reactome.org/PathwayBrowser/#/R-SSC-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Sus scrofa 58456 R-SSC-372697 https://reactome.org/PathwayBrowser/#/R-SSC-372697 Crk binding to p130cas IEA Sus scrofa 58456 R-SSC-372705 https://reactome.org/PathwayBrowser/#/R-SSC-372705 Recruitment of BCAR1 to PTK2 complex IEA Sus scrofa 58456 R-SSC-374662 https://reactome.org/PathwayBrowser/#/R-SSC-374662 Translocation of Ezrin to plasma membrane IEA Sus scrofa 58456 R-SSC-374663 https://reactome.org/PathwayBrowser/#/R-SSC-374663 DCC interaction with Ezrin IEA Sus scrofa 58456 R-SSC-374664 https://reactome.org/PathwayBrowser/#/R-SSC-374664 Phosphorylation and activation of Ezrin IEA Sus scrofa 58456 R-SSC-3772436 https://reactome.org/PathwayBrowser/#/R-SSC-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Sus scrofa 58456 R-SSC-377640 https://reactome.org/PathwayBrowser/#/R-SSC-377640 Autophosphorylation of SRC IEA Sus scrofa 58456 R-SSC-377641 https://reactome.org/PathwayBrowser/#/R-SSC-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Sus scrofa 58456 R-SSC-377643 https://reactome.org/PathwayBrowser/#/R-SSC-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Sus scrofa 58456 R-SSC-377644 https://reactome.org/PathwayBrowser/#/R-SSC-377644 Release of CSK from SRC IEA Sus scrofa 58456 R-SSC-389158 https://reactome.org/PathwayBrowser/#/R-SSC-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-392300 https://reactome.org/PathwayBrowser/#/R-SSC-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-3928595 https://reactome.org/PathwayBrowser/#/R-SSC-3928595 N-WASP binds ARP2/3 and G-actin IEA Sus scrofa 58456 R-SSC-3928601 https://reactome.org/PathwayBrowser/#/R-SSC-3928601 CDC42 and PIP2 bind WASL, activating it IEA Sus scrofa 58456 R-SSC-398193 https://reactome.org/PathwayBrowser/#/R-SSC-398193 PLC beta-mediated PIP2 hydrolysis IEA Sus scrofa 58456 R-SSC-399998 https://reactome.org/PathwayBrowser/#/R-SSC-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Sus scrofa 58456 R-SSC-429415 https://reactome.org/PathwayBrowser/#/R-SSC-429415 SYK binds to integrin alphaIIb beta3 IEA Sus scrofa 58456 R-SSC-429441 https://reactome.org/PathwayBrowser/#/R-SSC-429441 SYK activation by SRC IEA Sus scrofa 58456 R-SSC-432096 https://reactome.org/PathwayBrowser/#/R-SSC-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Sus scrofa 58456 R-SSC-437162 https://reactome.org/PathwayBrowser/#/R-SSC-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-442273 https://reactome.org/PathwayBrowser/#/R-SSC-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Sus scrofa 58456 R-SSC-443905 https://reactome.org/PathwayBrowser/#/R-SSC-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Sus scrofa 58456 R-SSC-443910 https://reactome.org/PathwayBrowser/#/R-SSC-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Sus scrofa 58456 R-SSC-449058 https://reactome.org/PathwayBrowser/#/R-SSC-449058 Interleukin-1 family are secreted IEA Sus scrofa 58456 R-SSC-5218819 https://reactome.org/PathwayBrowser/#/R-SSC-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-5607735 https://reactome.org/PathwayBrowser/#/R-SSC-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Sus scrofa 58456 R-SSC-5620975 https://reactome.org/PathwayBrowser/#/R-SSC-5620975 MLKL binds PIPs IEA Sus scrofa 58456 R-SSC-5654690 https://reactome.org/PathwayBrowser/#/R-SSC-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-5654692 https://reactome.org/PathwayBrowser/#/R-SSC-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-5654697 https://reactome.org/PathwayBrowser/#/R-SSC-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-5654701 https://reactome.org/PathwayBrowser/#/R-SSC-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-5654705 https://reactome.org/PathwayBrowser/#/R-SSC-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-5654709 https://reactome.org/PathwayBrowser/#/R-SSC-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-5654714 https://reactome.org/PathwayBrowser/#/R-SSC-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-5654717 https://reactome.org/PathwayBrowser/#/R-SSC-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-5672972 https://reactome.org/PathwayBrowser/#/R-SSC-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Sus scrofa 58456 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 58456 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 58456 R-SSC-5672980 https://reactome.org/PathwayBrowser/#/R-SSC-5672980 Dissociation of RAS:RAF complex IEA Sus scrofa 58456 R-SSC-6810410 https://reactome.org/PathwayBrowser/#/R-SSC-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Sus scrofa 58456 R-SSC-6811522 https://reactome.org/PathwayBrowser/#/R-SSC-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Sus scrofa 58456 R-SSC-8849969 https://reactome.org/PathwayBrowser/#/R-SSC-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Sus scrofa 58456 R-SSC-8852019 https://reactome.org/PathwayBrowser/#/R-SSC-8852019 MET bound PI3K generates PIP3 IEA Sus scrofa 58456 R-SSC-8856808 https://reactome.org/PathwayBrowser/#/R-SSC-8856808 Recruitment of AP-2 complex and clathrin IEA Sus scrofa 58456 R-SSC-8856813 https://reactome.org/PathwayBrowser/#/R-SSC-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Sus scrofa 58456 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa 58456 R-SSC-8867041 https://reactome.org/PathwayBrowser/#/R-SSC-8867041 EGFR phosphorylates EPS15 IEA Sus scrofa 58456 R-SSC-8867044 https://reactome.org/PathwayBrowser/#/R-SSC-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Sus scrofa 58456 R-SSC-8867047 https://reactome.org/PathwayBrowser/#/R-SSC-8867047 PTPN3 dephosphorylates EPS15 IEA Sus scrofa 58456 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa 58456 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa 58456 R-SSC-8868066 https://reactome.org/PathwayBrowser/#/R-SSC-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Sus scrofa 58456 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa 58456 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 58456 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa 58456 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa 58456 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 58456 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa 58456 R-SSC-8871196 https://reactome.org/PathwayBrowser/#/R-SSC-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Sus scrofa 58456 R-SSC-8874470 https://reactome.org/PathwayBrowser/#/R-SSC-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Sus scrofa 58456 R-SSC-9021627 https://reactome.org/PathwayBrowser/#/R-SSC-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa 58456 R-SSC-9647619 https://reactome.org/PathwayBrowser/#/R-SSC-9647619 GSDMD forms ring‐shaped oligomers IEA Sus scrofa 58456 R-SSC-9647631 https://reactome.org/PathwayBrowser/#/R-SSC-9647631 GSDMD (1-275) binds PIPs IEA Sus scrofa 58456 R-SSC-9647645 https://reactome.org/PathwayBrowser/#/R-SSC-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Sus scrofa 58456 R-SSC-9647660 https://reactome.org/PathwayBrowser/#/R-SSC-9647660 GSDME (1-270) binds PIPs IEA Sus scrofa 58456 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa 58456 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa 58456 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 58456 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa 58456 R-SSC-9710254 https://reactome.org/PathwayBrowser/#/R-SSC-9710254 GSDME oligomerizes IEA Sus scrofa 58456 R-XTR-109699 https://reactome.org/PathwayBrowser/#/R-XTR-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-111879 https://reactome.org/PathwayBrowser/#/R-XTR-111879 PIP2 hydrolysis IEA Xenopus tropicalis 58456 R-XTR-114688 https://reactome.org/PathwayBrowser/#/R-XTR-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Xenopus tropicalis 58456 R-XTR-114689 https://reactome.org/PathwayBrowser/#/R-XTR-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Xenopus tropicalis 58456 R-XTR-1250370 https://reactome.org/PathwayBrowser/#/R-XTR-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Xenopus tropicalis 58456 R-XTR-1306957 https://reactome.org/PathwayBrowser/#/R-XTR-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Xenopus tropicalis 58456 R-XTR-1306979 https://reactome.org/PathwayBrowser/#/R-XTR-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Xenopus tropicalis 58456 R-XTR-1433514 https://reactome.org/PathwayBrowser/#/R-XTR-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Xenopus tropicalis 58456 R-XTR-1675776 https://reactome.org/PathwayBrowser/#/R-XTR-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Xenopus tropicalis 58456 R-XTR-1675824 https://reactome.org/PathwayBrowser/#/R-XTR-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Xenopus tropicalis 58456 R-XTR-1676048 https://reactome.org/PathwayBrowser/#/R-XTR-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Xenopus tropicalis 58456 R-XTR-1676082 https://reactome.org/PathwayBrowser/#/R-XTR-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Xenopus tropicalis 58456 R-XTR-1676177 https://reactome.org/PathwayBrowser/#/R-XTR-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Xenopus tropicalis 58456 R-XTR-177939 https://reactome.org/PathwayBrowser/#/R-XTR-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Xenopus tropicalis 58456 R-XTR-1855177 https://reactome.org/PathwayBrowser/#/R-XTR-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Xenopus tropicalis 58456 R-XTR-1855214 https://reactome.org/PathwayBrowser/#/R-XTR-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Xenopus tropicalis 58456 R-XTR-1855221 https://reactome.org/PathwayBrowser/#/R-XTR-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Xenopus tropicalis 58456 R-XTR-186800 https://reactome.org/PathwayBrowser/#/R-XTR-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-198266 https://reactome.org/PathwayBrowser/#/R-XTR-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Xenopus tropicalis 58456 R-XTR-199456 https://reactome.org/PathwayBrowser/#/R-XTR-199456 PTEN dephosphorylates PIP3 IEA Xenopus tropicalis 58456 R-XTR-201510 https://reactome.org/PathwayBrowser/#/R-XTR-201510 PI3K synthesizes PIP3 downstream of ALK IEA Xenopus tropicalis 58456 R-XTR-202354 https://reactome.org/PathwayBrowser/#/R-XTR-202354 Translocation of PLC-gamma1 to PIP2 IEA Xenopus tropicalis 58456 R-XTR-202407 https://reactome.org/PathwayBrowser/#/R-XTR-202407 PLC-gamma1 hydrolyses PIP2 IEA Xenopus tropicalis 58456 R-XTR-2219524 https://reactome.org/PathwayBrowser/#/R-XTR-2219524 PDPK1 binds PIP2 IEA Xenopus tropicalis 58456 R-XTR-2316434 https://reactome.org/PathwayBrowser/#/R-XTR-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-2559456 https://reactome.org/PathwayBrowser/#/R-XTR-2559456 TIRAP binds PIP2-rich regions in the plasma membrane IEA Xenopus tropicalis 58456 R-XTR-2730847 https://reactome.org/PathwayBrowser/#/R-XTR-2730847 Hydrolysis of PIP2 by PLCG IEA Xenopus tropicalis 58456 R-XTR-2730870 https://reactome.org/PathwayBrowser/#/R-XTR-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Xenopus tropicalis 58456 R-XTR-354060 https://reactome.org/PathwayBrowser/#/R-XTR-354060 Translocation of RIAM to plasma membrane IEA Xenopus tropicalis 58456 R-XTR-354077 https://reactome.org/PathwayBrowser/#/R-XTR-354077 Integrin alphaIIb beta3 activation IEA Xenopus tropicalis 58456 R-XTR-354097 https://reactome.org/PathwayBrowser/#/R-XTR-354097 Activation of Talin IEA Xenopus tropicalis 58456 R-XTR-374662 https://reactome.org/PathwayBrowser/#/R-XTR-374662 Translocation of Ezrin to plasma membrane IEA Xenopus tropicalis 58456 R-XTR-374663 https://reactome.org/PathwayBrowser/#/R-XTR-374663 DCC interaction with Ezrin IEA Xenopus tropicalis 58456 R-XTR-374680 https://reactome.org/PathwayBrowser/#/R-XTR-374680 L1 trans-homophilic interaction IEA Xenopus tropicalis 58456 R-XTR-389158 https://reactome.org/PathwayBrowser/#/R-XTR-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-392300 https://reactome.org/PathwayBrowser/#/R-XTR-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-398193 https://reactome.org/PathwayBrowser/#/R-XTR-398193 PLC beta-mediated PIP2 hydrolysis IEA Xenopus tropicalis 58456 R-XTR-437162 https://reactome.org/PathwayBrowser/#/R-XTR-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-442273 https://reactome.org/PathwayBrowser/#/R-XTR-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Xenopus tropicalis 58456 R-XTR-443779 https://reactome.org/PathwayBrowser/#/R-XTR-443779 Linkage of L1 with treadmilling F-actin IEA Xenopus tropicalis 58456 R-XTR-443905 https://reactome.org/PathwayBrowser/#/R-XTR-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Xenopus tropicalis 58456 R-XTR-5218819 https://reactome.org/PathwayBrowser/#/R-XTR-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-5607735 https://reactome.org/PathwayBrowser/#/R-XTR-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Xenopus tropicalis 58456 R-XTR-5654690 https://reactome.org/PathwayBrowser/#/R-XTR-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-5654692 https://reactome.org/PathwayBrowser/#/R-XTR-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-5654697 https://reactome.org/PathwayBrowser/#/R-XTR-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-5654701 https://reactome.org/PathwayBrowser/#/R-XTR-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-5654705 https://reactome.org/PathwayBrowser/#/R-XTR-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-5654709 https://reactome.org/PathwayBrowser/#/R-XTR-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-5654714 https://reactome.org/PathwayBrowser/#/R-XTR-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-5654717 https://reactome.org/PathwayBrowser/#/R-XTR-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-6805981 https://reactome.org/PathwayBrowser/#/R-XTR-6805981 HMGB1 release from cells IEA Xenopus tropicalis 58456 R-XTR-6810410 https://reactome.org/PathwayBrowser/#/R-XTR-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Xenopus tropicalis 58456 R-XTR-6811522 https://reactome.org/PathwayBrowser/#/R-XTR-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Xenopus tropicalis 58456 R-XTR-8849969 https://reactome.org/PathwayBrowser/#/R-XTR-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Xenopus tropicalis 58456 R-XTR-8852019 https://reactome.org/PathwayBrowser/#/R-XTR-8852019 MET bound PI3K generates PIP3 IEA Xenopus tropicalis 58456 R-XTR-8868066 https://reactome.org/PathwayBrowser/#/R-XTR-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Xenopus tropicalis 58456 R-XTR-8874470 https://reactome.org/PathwayBrowser/#/R-XTR-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Xenopus tropicalis 58456 R-XTR-9021627 https://reactome.org/PathwayBrowser/#/R-XTR-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Xenopus tropicalis 58456 R-XTR-9647660 https://reactome.org/PathwayBrowser/#/R-XTR-9647660 GSDME (1-270) binds PIPs IEA Xenopus tropicalis 58456 R-XTR-9710254 https://reactome.org/PathwayBrowser/#/R-XTR-9710254 GSDME oligomerizes IEA Xenopus tropicalis 58462 R-BTA-1474146 https://reactome.org/PathwayBrowser/#/R-BTA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Bos taurus 58462 R-BTA-1474184 https://reactome.org/PathwayBrowser/#/R-BTA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Bos taurus 58462 R-CEL-1474146 https://reactome.org/PathwayBrowser/#/R-CEL-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Caenorhabditis elegans 58462 R-CEL-1474184 https://reactome.org/PathwayBrowser/#/R-CEL-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Caenorhabditis elegans 58462 R-CFA-1474146 https://reactome.org/PathwayBrowser/#/R-CFA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Canis familiaris 58462 R-DDI-1474146 https://reactome.org/PathwayBrowser/#/R-DDI-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Dictyostelium discoideum 58462 R-DDI-1474184 https://reactome.org/PathwayBrowser/#/R-DDI-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Dictyostelium discoideum 58462 R-DME-1474146 https://reactome.org/PathwayBrowser/#/R-DME-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Drosophila melanogaster 58462 R-DME-1474184 https://reactome.org/PathwayBrowser/#/R-DME-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Drosophila melanogaster 58462 R-DRE-1474184 https://reactome.org/PathwayBrowser/#/R-DRE-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Danio rerio 58462 R-GGA-1474146 https://reactome.org/PathwayBrowser/#/R-GGA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Gallus gallus 58462 R-GGA-1474184 https://reactome.org/PathwayBrowser/#/R-GGA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Gallus gallus 58462 R-HSA-1474146 https://reactome.org/PathwayBrowser/#/R-HSA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate TAS Homo sapiens 58462 R-HSA-1474184 https://reactome.org/PathwayBrowser/#/R-HSA-1474184 DHNTP is dephosphorylated by PTPS to PTHP TAS Homo sapiens 58462 R-MMU-1474146 https://reactome.org/PathwayBrowser/#/R-MMU-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Mus musculus 58462 R-MMU-1474184 https://reactome.org/PathwayBrowser/#/R-MMU-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Mus musculus 58462 R-PFA-1474184 https://reactome.org/PathwayBrowser/#/R-PFA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Plasmodium falciparum 58462 R-RNO-1474146 https://reactome.org/PathwayBrowser/#/R-RNO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Rattus norvegicus 58462 R-RNO-1474184 https://reactome.org/PathwayBrowser/#/R-RNO-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Rattus norvegicus 58462 R-SCE-1474146 https://reactome.org/PathwayBrowser/#/R-SCE-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Saccharomyces cerevisiae 58462 R-SPO-1474146 https://reactome.org/PathwayBrowser/#/R-SPO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Schizosaccharomyces pombe 58462 R-SSC-1474146 https://reactome.org/PathwayBrowser/#/R-SSC-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Sus scrofa 58462 R-SSC-1474184 https://reactome.org/PathwayBrowser/#/R-SSC-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Sus scrofa 58462 R-XTR-1474146 https://reactome.org/PathwayBrowser/#/R-XTR-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Xenopus tropicalis 58462 R-XTR-1474184 https://reactome.org/PathwayBrowser/#/R-XTR-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Xenopus tropicalis 58467 R-BTA-73797 https://reactome.org/PathwayBrowser/#/R-BTA-73797 FAICAR => IMP + H2O IEA Bos taurus 58467 R-BTA-73798 https://reactome.org/PathwayBrowser/#/R-BTA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Bos taurus 58467 R-CEL-73797 https://reactome.org/PathwayBrowser/#/R-CEL-73797 FAICAR => IMP + H2O IEA Caenorhabditis elegans 58467 R-CEL-73798 https://reactome.org/PathwayBrowser/#/R-CEL-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Caenorhabditis elegans 58467 R-CFA-73797 https://reactome.org/PathwayBrowser/#/R-CFA-73797 FAICAR => IMP + H2O IEA Canis familiaris 58467 R-CFA-73798 https://reactome.org/PathwayBrowser/#/R-CFA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Canis familiaris 58467 R-DDI-73797 https://reactome.org/PathwayBrowser/#/R-DDI-73797 FAICAR => IMP + H2O IEA Dictyostelium discoideum 58467 R-DDI-73798 https://reactome.org/PathwayBrowser/#/R-DDI-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Dictyostelium discoideum 58467 R-DME-73797 https://reactome.org/PathwayBrowser/#/R-DME-73797 FAICAR => IMP + H2O IEA Drosophila melanogaster 58467 R-DME-73798 https://reactome.org/PathwayBrowser/#/R-DME-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Drosophila melanogaster 58467 R-DRE-73797 https://reactome.org/PathwayBrowser/#/R-DRE-73797 FAICAR => IMP + H2O IEA Danio rerio 58467 R-DRE-73798 https://reactome.org/PathwayBrowser/#/R-DRE-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Danio rerio 58467 R-GGA-419253 https://reactome.org/PathwayBrowser/#/R-GGA-419253 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) <=> inosine 5'-monophosphate + H2O TAS Gallus gallus 58467 R-GGA-419254 https://reactome.org/PathwayBrowser/#/R-GGA-419254 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + 10-formyltetrahydrofolate => 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) + tetrahydrofolate TAS Gallus gallus 58467 R-GGA-73797 https://reactome.org/PathwayBrowser/#/R-GGA-73797 FAICAR => IMP + H2O IEA Gallus gallus 58467 R-GGA-73798 https://reactome.org/PathwayBrowser/#/R-GGA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Gallus gallus 58467 R-HSA-73797 https://reactome.org/PathwayBrowser/#/R-HSA-73797 FAICAR => IMP + H2O TAS Homo sapiens 58467 R-HSA-73798 https://reactome.org/PathwayBrowser/#/R-HSA-73798 AICAR + 10-Formyl-THF => FAICAR + THF TAS Homo sapiens 58467 R-MMU-73797 https://reactome.org/PathwayBrowser/#/R-MMU-73797 FAICAR => IMP + H2O IEA Mus musculus 58467 R-MMU-73798 https://reactome.org/PathwayBrowser/#/R-MMU-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Mus musculus 58467 R-RNO-73797 https://reactome.org/PathwayBrowser/#/R-RNO-73797 FAICAR => IMP + H2O IEA Rattus norvegicus 58467 R-RNO-73798 https://reactome.org/PathwayBrowser/#/R-RNO-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Rattus norvegicus 58467 R-SCE-73797 https://reactome.org/PathwayBrowser/#/R-SCE-73797 FAICAR => IMP + H2O IEA Saccharomyces cerevisiae 58467 R-SCE-73798 https://reactome.org/PathwayBrowser/#/R-SCE-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Saccharomyces cerevisiae 58467 R-SPO-73797 https://reactome.org/PathwayBrowser/#/R-SPO-73797 FAICAR => IMP + H2O IEA Schizosaccharomyces pombe 58467 R-SPO-73798 https://reactome.org/PathwayBrowser/#/R-SPO-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Schizosaccharomyces pombe 58467 R-SSC-73797 https://reactome.org/PathwayBrowser/#/R-SSC-73797 FAICAR => IMP + H2O IEA Sus scrofa 58467 R-SSC-73798 https://reactome.org/PathwayBrowser/#/R-SSC-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Sus scrofa 58471 R-BTA-159179 https://reactome.org/PathwayBrowser/#/R-BTA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Bos taurus 58471 R-BTA-5679041 https://reactome.org/PathwayBrowser/#/R-BTA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 58471 R-BTA-9661417 https://reactome.org/PathwayBrowser/#/R-BTA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 58471 R-CEL-5679041 https://reactome.org/PathwayBrowser/#/R-CEL-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 58471 R-CEL-9661417 https://reactome.org/PathwayBrowser/#/R-CEL-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 58471 R-CFA-5679041 https://reactome.org/PathwayBrowser/#/R-CFA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 58471 R-CFA-9661417 https://reactome.org/PathwayBrowser/#/R-CFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 58471 R-DDI-159179 https://reactome.org/PathwayBrowser/#/R-DDI-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Dictyostelium discoideum 58471 R-DDI-5679041 https://reactome.org/PathwayBrowser/#/R-DDI-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 58471 R-DDI-9632038 https://reactome.org/PathwayBrowser/#/R-DDI-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Dictyostelium discoideum 58471 R-DDI-9661417 https://reactome.org/PathwayBrowser/#/R-DDI-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 58471 R-DME-5679041 https://reactome.org/PathwayBrowser/#/R-DME-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 58471 R-DME-9661417 https://reactome.org/PathwayBrowser/#/R-DME-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 58471 R-DRE-5679041 https://reactome.org/PathwayBrowser/#/R-DRE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Danio rerio 58471 R-GGA-159179 https://reactome.org/PathwayBrowser/#/R-GGA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Gallus gallus 58471 R-GGA-5679041 https://reactome.org/PathwayBrowser/#/R-GGA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Gallus gallus 58471 R-GGA-9632038 https://reactome.org/PathwayBrowser/#/R-GGA-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Gallus gallus 58471 R-HSA-159179 https://reactome.org/PathwayBrowser/#/R-HSA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG TAS Homo sapiens 58471 R-HSA-5679031 https://reactome.org/PathwayBrowser/#/R-HSA-5679031 Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region TAS Homo sapiens 58471 R-HSA-5679041 https://reactome.org/PathwayBrowser/#/R-HSA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 58471 R-HSA-9632038 https://reactome.org/PathwayBrowser/#/R-HSA-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG TAS Homo sapiens 58471 R-HSA-9661417 https://reactome.org/PathwayBrowser/#/R-HSA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 58471 R-HSA-9661446 https://reactome.org/PathwayBrowser/#/R-HSA-9661446 BMG, BDG translocates from ER lumen to cytosol TAS Homo sapiens 58471 R-HSA-9661820 https://reactome.org/PathwayBrowser/#/R-HSA-9661820 Bacterial GUSB hydrolyses BDG to BIL TAS Homo sapiens 58471 R-MMU-159179 https://reactome.org/PathwayBrowser/#/R-MMU-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Mus musculus 58471 R-MMU-5679041 https://reactome.org/PathwayBrowser/#/R-MMU-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 58471 R-MMU-9632038 https://reactome.org/PathwayBrowser/#/R-MMU-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Mus musculus 58471 R-MMU-9661417 https://reactome.org/PathwayBrowser/#/R-MMU-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 58471 R-PFA-9661417 https://reactome.org/PathwayBrowser/#/R-PFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Plasmodium falciparum 58471 R-RNO-159179 https://reactome.org/PathwayBrowser/#/R-RNO-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Rattus norvegicus 58471 R-RNO-5679041 https://reactome.org/PathwayBrowser/#/R-RNO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 58471 R-RNO-9632038 https://reactome.org/PathwayBrowser/#/R-RNO-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG IEA Rattus norvegicus 58471 R-RNO-9661417 https://reactome.org/PathwayBrowser/#/R-RNO-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 58471 R-SCE-5679041 https://reactome.org/PathwayBrowser/#/R-SCE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 58471 R-SCE-9661417 https://reactome.org/PathwayBrowser/#/R-SCE-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 58471 R-SPO-5679041 https://reactome.org/PathwayBrowser/#/R-SPO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Schizosaccharomyces pombe 58471 R-SSC-159179 https://reactome.org/PathwayBrowser/#/R-SSC-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG IEA Sus scrofa 58471 R-SSC-5679041 https://reactome.org/PathwayBrowser/#/R-SSC-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 58471 R-SSC-9661417 https://reactome.org/PathwayBrowser/#/R-SSC-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 58471 R-XTR-5679041 https://reactome.org/PathwayBrowser/#/R-XTR-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 58471 R-XTR-9661417 https://reactome.org/PathwayBrowser/#/R-XTR-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 58475 R-BTA-73798 https://reactome.org/PathwayBrowser/#/R-BTA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Bos taurus 58475 R-BTA-73800 https://reactome.org/PathwayBrowser/#/R-BTA-73800 SAICAR => AICAR + Fumarate IEA Bos taurus 58475 R-CEL-73798 https://reactome.org/PathwayBrowser/#/R-CEL-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Caenorhabditis elegans 58475 R-CEL-73800 https://reactome.org/PathwayBrowser/#/R-CEL-73800 SAICAR => AICAR + Fumarate IEA Caenorhabditis elegans 58475 R-CFA-73798 https://reactome.org/PathwayBrowser/#/R-CFA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Canis familiaris 58475 R-CFA-73800 https://reactome.org/PathwayBrowser/#/R-CFA-73800 SAICAR => AICAR + Fumarate IEA Canis familiaris 58475 R-DDI-73798 https://reactome.org/PathwayBrowser/#/R-DDI-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Dictyostelium discoideum 58475 R-DME-73798 https://reactome.org/PathwayBrowser/#/R-DME-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Drosophila melanogaster 58475 R-DME-73800 https://reactome.org/PathwayBrowser/#/R-DME-73800 SAICAR => AICAR + Fumarate IEA Drosophila melanogaster 58475 R-DRE-73798 https://reactome.org/PathwayBrowser/#/R-DRE-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Danio rerio 58475 R-GGA-419254 https://reactome.org/PathwayBrowser/#/R-GGA-419254 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + 10-formyltetrahydrofolate => 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) + tetrahydrofolate TAS Gallus gallus 58475 R-GGA-419255 https://reactome.org/PathwayBrowser/#/R-GGA-419255 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + fumarate TAS Gallus gallus 58475 R-GGA-73798 https://reactome.org/PathwayBrowser/#/R-GGA-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Gallus gallus 58475 R-GGA-73800 https://reactome.org/PathwayBrowser/#/R-GGA-73800 SAICAR => AICAR + Fumarate IEA Gallus gallus 58475 R-HSA-73798 https://reactome.org/PathwayBrowser/#/R-HSA-73798 AICAR + 10-Formyl-THF => FAICAR + THF TAS Homo sapiens 58475 R-HSA-73800 https://reactome.org/PathwayBrowser/#/R-HSA-73800 SAICAR => AICAR + Fumarate TAS Homo sapiens 58475 R-MMU-73798 https://reactome.org/PathwayBrowser/#/R-MMU-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Mus musculus 58475 R-MMU-73800 https://reactome.org/PathwayBrowser/#/R-MMU-73800 SAICAR => AICAR + Fumarate IEA Mus musculus 58475 R-RNO-73798 https://reactome.org/PathwayBrowser/#/R-RNO-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Rattus norvegicus 58475 R-RNO-73800 https://reactome.org/PathwayBrowser/#/R-RNO-73800 SAICAR => AICAR + Fumarate IEA Rattus norvegicus 58475 R-SCE-73798 https://reactome.org/PathwayBrowser/#/R-SCE-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Saccharomyces cerevisiae 58475 R-SCE-73800 https://reactome.org/PathwayBrowser/#/R-SCE-73800 SAICAR => AICAR + Fumarate IEA Saccharomyces cerevisiae 58475 R-SPO-73798 https://reactome.org/PathwayBrowser/#/R-SPO-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Schizosaccharomyces pombe 58475 R-SPO-73800 https://reactome.org/PathwayBrowser/#/R-SPO-73800 SAICAR => AICAR + Fumarate IEA Schizosaccharomyces pombe 58475 R-SSC-73798 https://reactome.org/PathwayBrowser/#/R-SSC-73798 AICAR + 10-Formyl-THF => FAICAR + THF IEA Sus scrofa 58475 R-SSC-73800 https://reactome.org/PathwayBrowser/#/R-SSC-73800 SAICAR => AICAR + Fumarate IEA Sus scrofa 58475 R-XTR-73800 https://reactome.org/PathwayBrowser/#/R-XTR-73800 SAICAR => AICAR + Fumarate IEA Xenopus tropicalis 58509 R-BTA-6784224 https://reactome.org/PathwayBrowser/#/R-BTA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Bos taurus 58509 R-CEL-6784224 https://reactome.org/PathwayBrowser/#/R-CEL-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Caenorhabditis elegans 58509 R-CFA-6784224 https://reactome.org/PathwayBrowser/#/R-CFA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Canis familiaris 58509 R-DDI-6784224 https://reactome.org/PathwayBrowser/#/R-DDI-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Dictyostelium discoideum 58509 R-DME-6784224 https://reactome.org/PathwayBrowser/#/R-DME-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Drosophila melanogaster 58509 R-HSA-6784224 https://reactome.org/PathwayBrowser/#/R-HSA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate TAS Homo sapiens 58509 R-HSA-6784402 https://reactome.org/PathwayBrowser/#/R-HSA-6784402 Spontaneous hydrolysis of 1-pyrroline-3-hydroxy-5-carboxylate to 4-OH-L-glutamate semialdehyde TAS Homo sapiens 58509 R-MMU-6784224 https://reactome.org/PathwayBrowser/#/R-MMU-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Mus musculus 58509 R-RNO-6784224 https://reactome.org/PathwayBrowser/#/R-RNO-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Rattus norvegicus 58509 R-SCE-6784224 https://reactome.org/PathwayBrowser/#/R-SCE-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Saccharomyces cerevisiae 58509 R-SPO-6784224 https://reactome.org/PathwayBrowser/#/R-SPO-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Schizosaccharomyces pombe 58509 R-SSC-6784224 https://reactome.org/PathwayBrowser/#/R-SSC-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Sus scrofa 58509 R-XTR-6784224 https://reactome.org/PathwayBrowser/#/R-XTR-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Xenopus tropicalis 58527 R-BTA-8869606 https://reactome.org/PathwayBrowser/#/R-BTA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Bos taurus 58527 R-BTA-8869607 https://reactome.org/PathwayBrowser/#/R-BTA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Bos taurus 58527 R-CFA-8869606 https://reactome.org/PathwayBrowser/#/R-CFA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Canis familiaris 58527 R-DDI-8869606 https://reactome.org/PathwayBrowser/#/R-DDI-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 58527 R-DDI-8869607 https://reactome.org/PathwayBrowser/#/R-DDI-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 58527 R-DME-8869606 https://reactome.org/PathwayBrowser/#/R-DME-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 58527 R-DME-8869607 https://reactome.org/PathwayBrowser/#/R-DME-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 58527 R-DRE-8869607 https://reactome.org/PathwayBrowser/#/R-DRE-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Danio rerio 58527 R-GGA-8869606 https://reactome.org/PathwayBrowser/#/R-GGA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Gallus gallus 58527 R-GGA-8869607 https://reactome.org/PathwayBrowser/#/R-GGA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Gallus gallus 58527 R-HSA-8869606 https://reactome.org/PathwayBrowser/#/R-HSA-8869606 NMRK1 phosphorylates NAR to yield NAMN TAS Homo sapiens 58527 R-HSA-8869607 https://reactome.org/PathwayBrowser/#/R-HSA-8869607 NMRK2 phosphorylates NAR to yield NAMN TAS Homo sapiens 58527 R-MMU-8869606 https://reactome.org/PathwayBrowser/#/R-MMU-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Mus musculus 58527 R-MMU-8869607 https://reactome.org/PathwayBrowser/#/R-MMU-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Mus musculus 58527 R-RNO-8869606 https://reactome.org/PathwayBrowser/#/R-RNO-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Rattus norvegicus 58527 R-SSC-8869606 https://reactome.org/PathwayBrowser/#/R-SSC-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Sus scrofa 58527 R-SSC-8869607 https://reactome.org/PathwayBrowser/#/R-SSC-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Sus scrofa 58533 R-BTA-1237096 https://reactome.org/PathwayBrowser/#/R-BTA-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Bos taurus 58533 R-BTA-1237160 https://reactome.org/PathwayBrowser/#/R-BTA-1237160 MTA is cleaved and phosphorylated IEA Bos taurus 58533 R-BTA-1299507 https://reactome.org/PathwayBrowser/#/R-BTA-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Bos taurus 58533 R-CEL-1237096 https://reactome.org/PathwayBrowser/#/R-CEL-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Caenorhabditis elegans 58533 R-CEL-1237160 https://reactome.org/PathwayBrowser/#/R-CEL-1237160 MTA is cleaved and phosphorylated IEA Caenorhabditis elegans 58533 R-CEL-1299507 https://reactome.org/PathwayBrowser/#/R-CEL-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Caenorhabditis elegans 58533 R-CFA-1237096 https://reactome.org/PathwayBrowser/#/R-CFA-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Canis familiaris 58533 R-CFA-1237160 https://reactome.org/PathwayBrowser/#/R-CFA-1237160 MTA is cleaved and phosphorylated IEA Canis familiaris 58533 R-CFA-1299507 https://reactome.org/PathwayBrowser/#/R-CFA-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Canis familiaris 58533 R-DDI-1237096 https://reactome.org/PathwayBrowser/#/R-DDI-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Dictyostelium discoideum 58533 R-DDI-1299507 https://reactome.org/PathwayBrowser/#/R-DDI-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Dictyostelium discoideum 58533 R-DME-1237096 https://reactome.org/PathwayBrowser/#/R-DME-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Drosophila melanogaster 58533 R-DME-1237160 https://reactome.org/PathwayBrowser/#/R-DME-1237160 MTA is cleaved and phosphorylated IEA Drosophila melanogaster 58533 R-DME-1299507 https://reactome.org/PathwayBrowser/#/R-DME-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Drosophila melanogaster 58533 R-DRE-1237096 https://reactome.org/PathwayBrowser/#/R-DRE-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Danio rerio 58533 R-DRE-1237160 https://reactome.org/PathwayBrowser/#/R-DRE-1237160 MTA is cleaved and phosphorylated IEA Danio rerio 58533 R-DRE-1299507 https://reactome.org/PathwayBrowser/#/R-DRE-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Danio rerio 58533 R-GGA-1237096 https://reactome.org/PathwayBrowser/#/R-GGA-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Gallus gallus 58533 R-GGA-1237160 https://reactome.org/PathwayBrowser/#/R-GGA-1237160 MTA is cleaved and phosphorylated IEA Gallus gallus 58533 R-GGA-1299507 https://reactome.org/PathwayBrowser/#/R-GGA-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Gallus gallus 58533 R-HSA-1237096 https://reactome.org/PathwayBrowser/#/R-HSA-1237096 Methylthio-ribose-P = Methylthio-ribulose-P TAS Homo sapiens 58533 R-HSA-1237160 https://reactome.org/PathwayBrowser/#/R-HSA-1237160 MTA is cleaved and phosphorylated TAS Homo sapiens 58533 R-HSA-1299507 https://reactome.org/PathwayBrowser/#/R-HSA-1299507 Methylthio-ribulose-P = Methylthio-ribose-P TAS Homo sapiens 58533 R-MMU-1237096 https://reactome.org/PathwayBrowser/#/R-MMU-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Mus musculus 58533 R-MMU-1237160 https://reactome.org/PathwayBrowser/#/R-MMU-1237160 MTA is cleaved and phosphorylated IEA Mus musculus 58533 R-MMU-1299507 https://reactome.org/PathwayBrowser/#/R-MMU-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Mus musculus 58533 R-RNO-1237096 https://reactome.org/PathwayBrowser/#/R-RNO-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Rattus norvegicus 58533 R-RNO-1237160 https://reactome.org/PathwayBrowser/#/R-RNO-1237160 MTA is cleaved and phosphorylated IEA Rattus norvegicus 58533 R-RNO-1299507 https://reactome.org/PathwayBrowser/#/R-RNO-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Rattus norvegicus 58533 R-SCE-1237096 https://reactome.org/PathwayBrowser/#/R-SCE-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Saccharomyces cerevisiae 58533 R-SCE-1237160 https://reactome.org/PathwayBrowser/#/R-SCE-1237160 MTA is cleaved and phosphorylated IEA Saccharomyces cerevisiae 58533 R-SCE-1299507 https://reactome.org/PathwayBrowser/#/R-SCE-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Saccharomyces cerevisiae 58533 R-SPO-1237096 https://reactome.org/PathwayBrowser/#/R-SPO-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Schizosaccharomyces pombe 58533 R-SPO-1237160 https://reactome.org/PathwayBrowser/#/R-SPO-1237160 MTA is cleaved and phosphorylated IEA Schizosaccharomyces pombe 58533 R-SPO-1299507 https://reactome.org/PathwayBrowser/#/R-SPO-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Schizosaccharomyces pombe 58533 R-SSC-1237096 https://reactome.org/PathwayBrowser/#/R-SSC-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Sus scrofa 58533 R-SSC-1237160 https://reactome.org/PathwayBrowser/#/R-SSC-1237160 MTA is cleaved and phosphorylated IEA Sus scrofa 58533 R-SSC-1299507 https://reactome.org/PathwayBrowser/#/R-SSC-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Sus scrofa 58533 R-XTR-1237096 https://reactome.org/PathwayBrowser/#/R-XTR-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Xenopus tropicalis 58533 R-XTR-1237160 https://reactome.org/PathwayBrowser/#/R-XTR-1237160 MTA is cleaved and phosphorylated IEA Xenopus tropicalis 58533 R-XTR-1299507 https://reactome.org/PathwayBrowser/#/R-XTR-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Xenopus tropicalis 58539 R-BTA-198813 https://reactome.org/PathwayBrowser/#/R-BTA-198813 GSTO dimers reduce DeHA to AscH- IEA Bos taurus 58539 R-BTA-198818 https://reactome.org/PathwayBrowser/#/R-BTA-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Bos taurus 58539 R-BTA-209891 https://reactome.org/PathwayBrowser/#/R-BTA-209891 Dopamine is oxidised to noradrenaline IEA Bos taurus 58539 R-CEL-198813 https://reactome.org/PathwayBrowser/#/R-CEL-198813 GSTO dimers reduce DeHA to AscH- IEA Caenorhabditis elegans 58539 R-CEL-198818 https://reactome.org/PathwayBrowser/#/R-CEL-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Caenorhabditis elegans 58539 R-CFA-198813 https://reactome.org/PathwayBrowser/#/R-CFA-198813 GSTO dimers reduce DeHA to AscH- IEA Canis familiaris 58539 R-CFA-198818 https://reactome.org/PathwayBrowser/#/R-CFA-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Canis familiaris 58539 R-CFA-209891 https://reactome.org/PathwayBrowser/#/R-CFA-209891 Dopamine is oxidised to noradrenaline IEA Canis familiaris 58539 R-DDI-198818 https://reactome.org/PathwayBrowser/#/R-DDI-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Dictyostelium discoideum 58539 R-DME-198813 https://reactome.org/PathwayBrowser/#/R-DME-198813 GSTO dimers reduce DeHA to AscH- IEA Drosophila melanogaster 58539 R-DME-198818 https://reactome.org/PathwayBrowser/#/R-DME-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Drosophila melanogaster 58539 R-DME-209891 https://reactome.org/PathwayBrowser/#/R-DME-209891 Dopamine is oxidised to noradrenaline IEA Drosophila melanogaster 58539 R-DRE-198813 https://reactome.org/PathwayBrowser/#/R-DRE-198813 GSTO dimers reduce DeHA to AscH- IEA Danio rerio 58539 R-DRE-198818 https://reactome.org/PathwayBrowser/#/R-DRE-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Danio rerio 58539 R-DRE-209891 https://reactome.org/PathwayBrowser/#/R-DRE-209891 Dopamine is oxidised to noradrenaline IEA Danio rerio 58539 R-GGA-198813 https://reactome.org/PathwayBrowser/#/R-GGA-198813 GSTO dimers reduce DeHA to AscH- IEA Gallus gallus 58539 R-GGA-198818 https://reactome.org/PathwayBrowser/#/R-GGA-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Gallus gallus 58539 R-GGA-209891 https://reactome.org/PathwayBrowser/#/R-GGA-209891 Dopamine is oxidised to noradrenaline IEA Gallus gallus 58539 R-HSA-198813 https://reactome.org/PathwayBrowser/#/R-HSA-198813 GSTO dimers reduce DeHA to AscH- TAS Homo sapiens 58539 R-HSA-198818 https://reactome.org/PathwayBrowser/#/R-HSA-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol TAS Homo sapiens 58539 R-HSA-209891 https://reactome.org/PathwayBrowser/#/R-HSA-209891 Dopamine is oxidised to noradrenaline TAS Homo sapiens 58539 R-HSA-9640302 https://reactome.org/PathwayBrowser/#/R-HSA-9640302 Asc.- radical dissociates to AscH- and DeHA TAS Homo sapiens 58539 R-HSA-9640307 https://reactome.org/PathwayBrowser/#/R-HSA-9640307 DeHA hydrolyses to 2,3-DKG TAS Homo sapiens 58539 R-HSA-9640316 https://reactome.org/PathwayBrowser/#/R-HSA-9640316 DeHA hydrolyses to threonate and oxalate TAS Homo sapiens 58539 R-MMU-198813 https://reactome.org/PathwayBrowser/#/R-MMU-198813 GSTO dimers reduce DeHA to AscH- IEA Mus musculus 58539 R-MMU-198818 https://reactome.org/PathwayBrowser/#/R-MMU-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Mus musculus 58539 R-MMU-209891 https://reactome.org/PathwayBrowser/#/R-MMU-209891 Dopamine is oxidised to noradrenaline IEA Mus musculus 58539 R-PFA-198818 https://reactome.org/PathwayBrowser/#/R-PFA-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Plasmodium falciparum 58539 R-RNO-198813 https://reactome.org/PathwayBrowser/#/R-RNO-198813 GSTO dimers reduce DeHA to AscH- IEA Rattus norvegicus 58539 R-RNO-198818 https://reactome.org/PathwayBrowser/#/R-RNO-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Rattus norvegicus 58539 R-RNO-209891 https://reactome.org/PathwayBrowser/#/R-RNO-209891 Dopamine is oxidised to noradrenaline IEA Rattus norvegicus 58539 R-SCE-198818 https://reactome.org/PathwayBrowser/#/R-SCE-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Saccharomyces cerevisiae 58539 R-SSC-198813 https://reactome.org/PathwayBrowser/#/R-SSC-198813 GSTO dimers reduce DeHA to AscH- IEA Sus scrofa 58539 R-SSC-198818 https://reactome.org/PathwayBrowser/#/R-SSC-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Sus scrofa 58539 R-SSC-209891 https://reactome.org/PathwayBrowser/#/R-SSC-209891 Dopamine is oxidised to noradrenaline IEA Sus scrofa 58539 R-XTR-198813 https://reactome.org/PathwayBrowser/#/R-XTR-198813 GSTO dimers reduce DeHA to AscH- IEA Xenopus tropicalis 58539 R-XTR-198818 https://reactome.org/PathwayBrowser/#/R-XTR-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Xenopus tropicalis 58539 R-XTR-209891 https://reactome.org/PathwayBrowser/#/R-XTR-209891 Dopamine is oxidised to noradrenaline IEA Xenopus tropicalis 58548 R-BTA-1237096 https://reactome.org/PathwayBrowser/#/R-BTA-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Bos taurus 58548 R-BTA-1299507 https://reactome.org/PathwayBrowser/#/R-BTA-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Bos taurus 58548 R-CEL-1237096 https://reactome.org/PathwayBrowser/#/R-CEL-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Caenorhabditis elegans 58548 R-CEL-1299507 https://reactome.org/PathwayBrowser/#/R-CEL-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Caenorhabditis elegans 58548 R-CFA-1237096 https://reactome.org/PathwayBrowser/#/R-CFA-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Canis familiaris 58548 R-CFA-1299507 https://reactome.org/PathwayBrowser/#/R-CFA-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Canis familiaris 58548 R-DDI-1237096 https://reactome.org/PathwayBrowser/#/R-DDI-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Dictyostelium discoideum 58548 R-DDI-1299507 https://reactome.org/PathwayBrowser/#/R-DDI-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Dictyostelium discoideum 58548 R-DME-1237096 https://reactome.org/PathwayBrowser/#/R-DME-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Drosophila melanogaster 58548 R-DME-1299507 https://reactome.org/PathwayBrowser/#/R-DME-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Drosophila melanogaster 58548 R-DRE-1237096 https://reactome.org/PathwayBrowser/#/R-DRE-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Danio rerio 58548 R-DRE-1299507 https://reactome.org/PathwayBrowser/#/R-DRE-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Danio rerio 58548 R-GGA-1237096 https://reactome.org/PathwayBrowser/#/R-GGA-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Gallus gallus 58548 R-GGA-1299507 https://reactome.org/PathwayBrowser/#/R-GGA-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Gallus gallus 58548 R-HSA-1237096 https://reactome.org/PathwayBrowser/#/R-HSA-1237096 Methylthio-ribose-P = Methylthio-ribulose-P TAS Homo sapiens 58548 R-HSA-1237140 https://reactome.org/PathwayBrowser/#/R-HSA-1237140 Dehydration of methylthio-ribulose-P IEA Homo sapiens 58548 R-HSA-1299507 https://reactome.org/PathwayBrowser/#/R-HSA-1299507 Methylthio-ribulose-P = Methylthio-ribose-P TAS Homo sapiens 58548 R-MMU-1237096 https://reactome.org/PathwayBrowser/#/R-MMU-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Mus musculus 58548 R-MMU-1299507 https://reactome.org/PathwayBrowser/#/R-MMU-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Mus musculus 58548 R-RNO-1237096 https://reactome.org/PathwayBrowser/#/R-RNO-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Rattus norvegicus 58548 R-RNO-1299507 https://reactome.org/PathwayBrowser/#/R-RNO-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Rattus norvegicus 58548 R-SCE-1237096 https://reactome.org/PathwayBrowser/#/R-SCE-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Saccharomyces cerevisiae 58548 R-SCE-1237121 https://reactome.org/PathwayBrowser/#/R-SCE-1237121 Dehydration of methylthio-ribulose-P TAS Saccharomyces cerevisiae 58548 R-SCE-1299507 https://reactome.org/PathwayBrowser/#/R-SCE-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Saccharomyces cerevisiae 58548 R-SPO-1237096 https://reactome.org/PathwayBrowser/#/R-SPO-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Schizosaccharomyces pombe 58548 R-SPO-1299507 https://reactome.org/PathwayBrowser/#/R-SPO-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Schizosaccharomyces pombe 58548 R-SSC-1237096 https://reactome.org/PathwayBrowser/#/R-SSC-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Sus scrofa 58548 R-SSC-1299507 https://reactome.org/PathwayBrowser/#/R-SSC-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Sus scrofa 58548 R-XTR-1237096 https://reactome.org/PathwayBrowser/#/R-XTR-1237096 Methylthio-ribose-P = Methylthio-ribulose-P IEA Xenopus tropicalis 58548 R-XTR-1299507 https://reactome.org/PathwayBrowser/#/R-XTR-1299507 Methylthio-ribulose-P = Methylthio-ribose-P IEA Xenopus tropicalis 5856 R-BTA-9613264 https://reactome.org/PathwayBrowser/#/R-BTA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Bos taurus 5856 R-CFA-9613264 https://reactome.org/PathwayBrowser/#/R-CFA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Canis familiaris 5856 R-GGA-9613264 https://reactome.org/PathwayBrowser/#/R-GGA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Gallus gallus 5856 R-HSA-9613264 https://reactome.org/PathwayBrowser/#/R-HSA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE TAS Homo sapiens 5856 R-MMU-9613264 https://reactome.org/PathwayBrowser/#/R-MMU-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Mus musculus 5856 R-RNO-9613264 https://reactome.org/PathwayBrowser/#/R-RNO-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Rattus norvegicus 5856 R-SSC-9613264 https://reactome.org/PathwayBrowser/#/R-SSC-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Sus scrofa 58576 R-BTA-112033 https://reactome.org/PathwayBrowser/#/R-BTA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Bos taurus 58576 R-BTA-112034 https://reactome.org/PathwayBrowser/#/R-BTA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Bos taurus 58576 R-BTA-74242 https://reactome.org/PathwayBrowser/#/R-BTA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Bos taurus 58576 R-BTA-74249 https://reactome.org/PathwayBrowser/#/R-BTA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Bos taurus 58576 R-BTA-74372 https://reactome.org/PathwayBrowser/#/R-BTA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Bos taurus 58576 R-BTA-74376 https://reactome.org/PathwayBrowser/#/R-BTA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Bos taurus 58576 R-CEL-112033 https://reactome.org/PathwayBrowser/#/R-CEL-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Caenorhabditis elegans 58576 R-CEL-112034 https://reactome.org/PathwayBrowser/#/R-CEL-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Caenorhabditis elegans 58576 R-CEL-74242 https://reactome.org/PathwayBrowser/#/R-CEL-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Caenorhabditis elegans 58576 R-CEL-74249 https://reactome.org/PathwayBrowser/#/R-CEL-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Caenorhabditis elegans 58576 R-CEL-74372 https://reactome.org/PathwayBrowser/#/R-CEL-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Caenorhabditis elegans 58576 R-CEL-74376 https://reactome.org/PathwayBrowser/#/R-CEL-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Caenorhabditis elegans 58576 R-CFA-112033 https://reactome.org/PathwayBrowser/#/R-CFA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Canis familiaris 58576 R-CFA-112034 https://reactome.org/PathwayBrowser/#/R-CFA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Canis familiaris 58576 R-CFA-74242 https://reactome.org/PathwayBrowser/#/R-CFA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Canis familiaris 58576 R-CFA-74249 https://reactome.org/PathwayBrowser/#/R-CFA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Canis familiaris 58576 R-CFA-74372 https://reactome.org/PathwayBrowser/#/R-CFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Canis familiaris 58576 R-CFA-74376 https://reactome.org/PathwayBrowser/#/R-CFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Canis familiaris 58576 R-DDI-74372 https://reactome.org/PathwayBrowser/#/R-DDI-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Dictyostelium discoideum 58576 R-DDI-74376 https://reactome.org/PathwayBrowser/#/R-DDI-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Dictyostelium discoideum 58576 R-DME-112033 https://reactome.org/PathwayBrowser/#/R-DME-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Drosophila melanogaster 58576 R-DME-112034 https://reactome.org/PathwayBrowser/#/R-DME-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Drosophila melanogaster 58576 R-DME-74242 https://reactome.org/PathwayBrowser/#/R-DME-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Drosophila melanogaster 58576 R-DME-74249 https://reactome.org/PathwayBrowser/#/R-DME-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Drosophila melanogaster 58576 R-DME-74372 https://reactome.org/PathwayBrowser/#/R-DME-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Drosophila melanogaster 58576 R-DME-74376 https://reactome.org/PathwayBrowser/#/R-DME-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Drosophila melanogaster 58576 R-DRE-112033 https://reactome.org/PathwayBrowser/#/R-DRE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Danio rerio 58576 R-DRE-112034 https://reactome.org/PathwayBrowser/#/R-DRE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Danio rerio 58576 R-DRE-74242 https://reactome.org/PathwayBrowser/#/R-DRE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Danio rerio 58576 R-DRE-74249 https://reactome.org/PathwayBrowser/#/R-DRE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Danio rerio 58576 R-DRE-74372 https://reactome.org/PathwayBrowser/#/R-DRE-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Danio rerio 58576 R-DRE-74376 https://reactome.org/PathwayBrowser/#/R-DRE-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Danio rerio 58576 R-GGA-74372 https://reactome.org/PathwayBrowser/#/R-GGA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Gallus gallus 58576 R-GGA-74376 https://reactome.org/PathwayBrowser/#/R-GGA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Gallus gallus 58576 R-HSA-112033 https://reactome.org/PathwayBrowser/#/R-HSA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine TAS Homo sapiens 58576 R-HSA-112034 https://reactome.org/PathwayBrowser/#/R-HSA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine TAS Homo sapiens 58576 R-HSA-112265 https://reactome.org/PathwayBrowser/#/R-HSA-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] TAS Homo sapiens 58576 R-HSA-112266 https://reactome.org/PathwayBrowser/#/R-HSA-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] TAS Homo sapiens 58576 R-HSA-74242 https://reactome.org/PathwayBrowser/#/R-HSA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 58576 R-HSA-74249 https://reactome.org/PathwayBrowser/#/R-HSA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 58576 R-HSA-74372 https://reactome.org/PathwayBrowser/#/R-HSA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] TAS Homo sapiens 58576 R-HSA-74376 https://reactome.org/PathwayBrowser/#/R-HSA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) TAS Homo sapiens 58576 R-MMU-112033 https://reactome.org/PathwayBrowser/#/R-MMU-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Mus musculus 58576 R-MMU-112034 https://reactome.org/PathwayBrowser/#/R-MMU-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Mus musculus 58576 R-MMU-112265 https://reactome.org/PathwayBrowser/#/R-MMU-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Mus musculus 58576 R-MMU-112266 https://reactome.org/PathwayBrowser/#/R-MMU-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Mus musculus 58576 R-MMU-74242 https://reactome.org/PathwayBrowser/#/R-MMU-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Mus musculus 58576 R-MMU-74249 https://reactome.org/PathwayBrowser/#/R-MMU-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Mus musculus 58576 R-MMU-74372 https://reactome.org/PathwayBrowser/#/R-MMU-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Mus musculus 58576 R-MMU-74376 https://reactome.org/PathwayBrowser/#/R-MMU-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Mus musculus 58576 R-PFA-74372 https://reactome.org/PathwayBrowser/#/R-PFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Plasmodium falciparum 58576 R-PFA-74376 https://reactome.org/PathwayBrowser/#/R-PFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Plasmodium falciparum 58576 R-RNO-112033 https://reactome.org/PathwayBrowser/#/R-RNO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Rattus norvegicus 58576 R-RNO-112034 https://reactome.org/PathwayBrowser/#/R-RNO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Rattus norvegicus 58576 R-RNO-112265 https://reactome.org/PathwayBrowser/#/R-RNO-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Rattus norvegicus 58576 R-RNO-112266 https://reactome.org/PathwayBrowser/#/R-RNO-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Rattus norvegicus 58576 R-RNO-74242 https://reactome.org/PathwayBrowser/#/R-RNO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Rattus norvegicus 58576 R-RNO-74249 https://reactome.org/PathwayBrowser/#/R-RNO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Rattus norvegicus 58576 R-RNO-74372 https://reactome.org/PathwayBrowser/#/R-RNO-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Rattus norvegicus 58576 R-RNO-74376 https://reactome.org/PathwayBrowser/#/R-RNO-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Rattus norvegicus 58576 R-SCE-112033 https://reactome.org/PathwayBrowser/#/R-SCE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Saccharomyces cerevisiae 58576 R-SCE-112034 https://reactome.org/PathwayBrowser/#/R-SCE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Saccharomyces cerevisiae 58576 R-SCE-74242 https://reactome.org/PathwayBrowser/#/R-SCE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Saccharomyces cerevisiae 58576 R-SCE-74249 https://reactome.org/PathwayBrowser/#/R-SCE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Saccharomyces cerevisiae 58576 R-SPO-112033 https://reactome.org/PathwayBrowser/#/R-SPO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Schizosaccharomyces pombe 58576 R-SPO-112034 https://reactome.org/PathwayBrowser/#/R-SPO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Schizosaccharomyces pombe 58576 R-SPO-74242 https://reactome.org/PathwayBrowser/#/R-SPO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Schizosaccharomyces pombe 58576 R-SPO-74249 https://reactome.org/PathwayBrowser/#/R-SPO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Schizosaccharomyces pombe 58576 R-SSC-112033 https://reactome.org/PathwayBrowser/#/R-SSC-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Sus scrofa 58576 R-SSC-112034 https://reactome.org/PathwayBrowser/#/R-SSC-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Sus scrofa 58576 R-SSC-74242 https://reactome.org/PathwayBrowser/#/R-SSC-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Sus scrofa 58576 R-SSC-74249 https://reactome.org/PathwayBrowser/#/R-SSC-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Sus scrofa 58576 R-SSC-74372 https://reactome.org/PathwayBrowser/#/R-SSC-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Sus scrofa 58576 R-SSC-74376 https://reactome.org/PathwayBrowser/#/R-SSC-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Sus scrofa 58576 R-XTR-112033 https://reactome.org/PathwayBrowser/#/R-XTR-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Xenopus tropicalis 58576 R-XTR-112034 https://reactome.org/PathwayBrowser/#/R-XTR-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Xenopus tropicalis 58576 R-XTR-112265 https://reactome.org/PathwayBrowser/#/R-XTR-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Xenopus tropicalis 58576 R-XTR-112266 https://reactome.org/PathwayBrowser/#/R-XTR-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Xenopus tropicalis 58576 R-XTR-74242 https://reactome.org/PathwayBrowser/#/R-XTR-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Xenopus tropicalis 58576 R-XTR-74249 https://reactome.org/PathwayBrowser/#/R-XTR-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Xenopus tropicalis 58576 R-XTR-74372 https://reactome.org/PathwayBrowser/#/R-XTR-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Xenopus tropicalis 58576 R-XTR-74376 https://reactome.org/PathwayBrowser/#/R-XTR-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Xenopus tropicalis 58593 R-BTA-110137 https://reactome.org/PathwayBrowser/#/R-BTA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Bos taurus 58593 R-BTA-110138 https://reactome.org/PathwayBrowser/#/R-BTA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 58593 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 58593 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 58593 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 58593 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 58593 R-BTA-6788798 https://reactome.org/PathwayBrowser/#/R-BTA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 58593 R-BTA-6788810 https://reactome.org/PathwayBrowser/#/R-BTA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 58593 R-BTA-73548 https://reactome.org/PathwayBrowser/#/R-BTA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Bos taurus 58593 R-BTA-75125 https://reactome.org/PathwayBrowser/#/R-BTA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Bos taurus 58593 R-CEL-110137 https://reactome.org/PathwayBrowser/#/R-CEL-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Caenorhabditis elegans 58593 R-CEL-110138 https://reactome.org/PathwayBrowser/#/R-CEL-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 58593 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 58593 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 58593 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 58593 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 58593 R-CEL-6788810 https://reactome.org/PathwayBrowser/#/R-CEL-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 58593 R-CEL-73548 https://reactome.org/PathwayBrowser/#/R-CEL-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Caenorhabditis elegans 58593 R-CEL-75125 https://reactome.org/PathwayBrowser/#/R-CEL-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Caenorhabditis elegans 58593 R-CFA-110137 https://reactome.org/PathwayBrowser/#/R-CFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Canis familiaris 58593 R-CFA-110138 https://reactome.org/PathwayBrowser/#/R-CFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 58593 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 58593 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 58593 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 58593 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 58593 R-CFA-6788798 https://reactome.org/PathwayBrowser/#/R-CFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 58593 R-CFA-6788810 https://reactome.org/PathwayBrowser/#/R-CFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 58593 R-CFA-73548 https://reactome.org/PathwayBrowser/#/R-CFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Canis familiaris 58593 R-CFA-75125 https://reactome.org/PathwayBrowser/#/R-CFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Canis familiaris 58593 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 58593 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 58593 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 58593 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 58593 R-DDI-6788798 https://reactome.org/PathwayBrowser/#/R-DDI-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 58593 R-DDI-6788810 https://reactome.org/PathwayBrowser/#/R-DDI-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 58593 R-DDI-73548 https://reactome.org/PathwayBrowser/#/R-DDI-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Dictyostelium discoideum 58593 R-DDI-75125 https://reactome.org/PathwayBrowser/#/R-DDI-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Dictyostelium discoideum 58593 R-DME-110137 https://reactome.org/PathwayBrowser/#/R-DME-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Drosophila melanogaster 58593 R-DME-110138 https://reactome.org/PathwayBrowser/#/R-DME-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 58593 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 58593 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 58593 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 58593 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 58593 R-DME-6788798 https://reactome.org/PathwayBrowser/#/R-DME-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 58593 R-DME-6788810 https://reactome.org/PathwayBrowser/#/R-DME-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 58593 R-DME-73548 https://reactome.org/PathwayBrowser/#/R-DME-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Drosophila melanogaster 58593 R-DME-75125 https://reactome.org/PathwayBrowser/#/R-DME-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Drosophila melanogaster 58593 R-DRE-110137 https://reactome.org/PathwayBrowser/#/R-DRE-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Danio rerio 58593 R-DRE-110138 https://reactome.org/PathwayBrowser/#/R-DRE-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 58593 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 58593 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 58593 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 58593 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 58593 R-DRE-6788798 https://reactome.org/PathwayBrowser/#/R-DRE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 58593 R-DRE-6788810 https://reactome.org/PathwayBrowser/#/R-DRE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 58593 R-DRE-73548 https://reactome.org/PathwayBrowser/#/R-DRE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Danio rerio 58593 R-DRE-75125 https://reactome.org/PathwayBrowser/#/R-DRE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Danio rerio 58593 R-GGA-110137 https://reactome.org/PathwayBrowser/#/R-GGA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Gallus gallus 58593 R-GGA-110138 https://reactome.org/PathwayBrowser/#/R-GGA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 58593 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 58593 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 58593 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 58593 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 58593 R-GGA-6788798 https://reactome.org/PathwayBrowser/#/R-GGA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 58593 R-GGA-6788810 https://reactome.org/PathwayBrowser/#/R-GGA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 58593 R-GGA-73548 https://reactome.org/PathwayBrowser/#/R-GGA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Gallus gallus 58593 R-GGA-75125 https://reactome.org/PathwayBrowser/#/R-GGA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Gallus gallus 58593 R-HSA-110137 https://reactome.org/PathwayBrowser/#/R-HSA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP TAS Homo sapiens 58593 R-HSA-110138 https://reactome.org/PathwayBrowser/#/R-HSA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 58593 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 58593 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 58593 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 58593 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 58593 R-HSA-6788798 https://reactome.org/PathwayBrowser/#/R-HSA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 58593 R-HSA-6788810 https://reactome.org/PathwayBrowser/#/R-HSA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 58593 R-HSA-73548 https://reactome.org/PathwayBrowser/#/R-HSA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) TAS Homo sapiens 58593 R-HSA-75125 https://reactome.org/PathwayBrowser/#/R-HSA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) TAS Homo sapiens 58593 R-MMU-110137 https://reactome.org/PathwayBrowser/#/R-MMU-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Mus musculus 58593 R-MMU-110138 https://reactome.org/PathwayBrowser/#/R-MMU-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 58593 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 58593 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 58593 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 58593 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 58593 R-MMU-6788798 https://reactome.org/PathwayBrowser/#/R-MMU-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 58593 R-MMU-6788810 https://reactome.org/PathwayBrowser/#/R-MMU-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 58593 R-MMU-73548 https://reactome.org/PathwayBrowser/#/R-MMU-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Mus musculus 58593 R-MMU-75125 https://reactome.org/PathwayBrowser/#/R-MMU-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Mus musculus 58593 R-PFA-110137 https://reactome.org/PathwayBrowser/#/R-PFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Plasmodium falciparum 58593 R-PFA-110138 https://reactome.org/PathwayBrowser/#/R-PFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 58593 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 58593 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 58593 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 58593 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 58593 R-PFA-6788798 https://reactome.org/PathwayBrowser/#/R-PFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 58593 R-PFA-6788810 https://reactome.org/PathwayBrowser/#/R-PFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 58593 R-PFA-73548 https://reactome.org/PathwayBrowser/#/R-PFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Plasmodium falciparum 58593 R-PFA-75125 https://reactome.org/PathwayBrowser/#/R-PFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Plasmodium falciparum 58593 R-RNO-110137 https://reactome.org/PathwayBrowser/#/R-RNO-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Rattus norvegicus 58593 R-RNO-110138 https://reactome.org/PathwayBrowser/#/R-RNO-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 58593 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 58593 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 58593 R-RNO-6788798 https://reactome.org/PathwayBrowser/#/R-RNO-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 58593 R-RNO-6788810 https://reactome.org/PathwayBrowser/#/R-RNO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 58593 R-RNO-73548 https://reactome.org/PathwayBrowser/#/R-RNO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Rattus norvegicus 58593 R-RNO-75125 https://reactome.org/PathwayBrowser/#/R-RNO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Rattus norvegicus 58593 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 58593 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 58593 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 58593 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 58593 R-SCE-6788798 https://reactome.org/PathwayBrowser/#/R-SCE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 58593 R-SCE-6788810 https://reactome.org/PathwayBrowser/#/R-SCE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 58593 R-SCE-73548 https://reactome.org/PathwayBrowser/#/R-SCE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Saccharomyces cerevisiae 58593 R-SCE-75125 https://reactome.org/PathwayBrowser/#/R-SCE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Saccharomyces cerevisiae 58593 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 58593 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 58593 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 58593 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 58593 R-SPO-6788810 https://reactome.org/PathwayBrowser/#/R-SPO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Schizosaccharomyces pombe 58593 R-SPO-73548 https://reactome.org/PathwayBrowser/#/R-SPO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Schizosaccharomyces pombe 58593 R-SPO-75125 https://reactome.org/PathwayBrowser/#/R-SPO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Schizosaccharomyces pombe 58593 R-SSC-110137 https://reactome.org/PathwayBrowser/#/R-SSC-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Sus scrofa 58593 R-SSC-110138 https://reactome.org/PathwayBrowser/#/R-SSC-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 58593 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 58593 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 58593 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 58593 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 58593 R-SSC-6788798 https://reactome.org/PathwayBrowser/#/R-SSC-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 58593 R-SSC-6788810 https://reactome.org/PathwayBrowser/#/R-SSC-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 58593 R-SSC-73548 https://reactome.org/PathwayBrowser/#/R-SSC-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Sus scrofa 58593 R-SSC-75125 https://reactome.org/PathwayBrowser/#/R-SSC-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Sus scrofa 58593 R-XTR-110137 https://reactome.org/PathwayBrowser/#/R-XTR-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Xenopus tropicalis 58593 R-XTR-110138 https://reactome.org/PathwayBrowser/#/R-XTR-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 58593 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 58593 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 58593 R-XTR-6788798 https://reactome.org/PathwayBrowser/#/R-XTR-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 58593 R-XTR-6788810 https://reactome.org/PathwayBrowser/#/R-XTR-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 585948 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 585948 R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 585948 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 585948 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 585948 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 585948 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 585948 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 585948 R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 585948 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 585948 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 585948 R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 585948 R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 585948 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 585948 R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 585948 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 58595 R-BTA-110133 https://reactome.org/PathwayBrowser/#/R-BTA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Bos taurus 58595 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 58595 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 58595 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 58595 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 58595 R-BTA-73788 https://reactome.org/PathwayBrowser/#/R-BTA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Bos taurus 58595 R-CEL-110133 https://reactome.org/PathwayBrowser/#/R-CEL-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Caenorhabditis elegans 58595 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 58595 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 58595 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 58595 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 58595 R-CEL-73788 https://reactome.org/PathwayBrowser/#/R-CEL-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Caenorhabditis elegans 58595 R-CFA-110133 https://reactome.org/PathwayBrowser/#/R-CFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Canis familiaris 58595 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 58595 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 58595 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 58595 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 58595 R-CFA-73788 https://reactome.org/PathwayBrowser/#/R-CFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Canis familiaris 58595 R-DDI-110133 https://reactome.org/PathwayBrowser/#/R-DDI-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Dictyostelium discoideum 58595 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 58595 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 58595 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 58595 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 58595 R-DDI-73788 https://reactome.org/PathwayBrowser/#/R-DDI-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Dictyostelium discoideum 58595 R-DME-110133 https://reactome.org/PathwayBrowser/#/R-DME-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Drosophila melanogaster 58595 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 58595 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 58595 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 58595 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 58595 R-DME-73788 https://reactome.org/PathwayBrowser/#/R-DME-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Drosophila melanogaster 58595 R-DRE-110133 https://reactome.org/PathwayBrowser/#/R-DRE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Danio rerio 58595 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 58595 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 58595 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 58595 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 58595 R-DRE-73788 https://reactome.org/PathwayBrowser/#/R-DRE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Danio rerio 58595 R-GGA-110133 https://reactome.org/PathwayBrowser/#/R-GGA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Gallus gallus 58595 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 58595 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 58595 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 58595 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 58595 R-GGA-73788 https://reactome.org/PathwayBrowser/#/R-GGA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Gallus gallus 58595 R-HSA-110133 https://reactome.org/PathwayBrowser/#/R-HSA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) TAS Homo sapiens 58595 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 58595 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 58595 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 58595 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 58595 R-HSA-73788 https://reactome.org/PathwayBrowser/#/R-HSA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) TAS Homo sapiens 58595 R-MMU-110133 https://reactome.org/PathwayBrowser/#/R-MMU-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Mus musculus 58595 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 58595 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 58595 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 58595 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 58595 R-MMU-73788 https://reactome.org/PathwayBrowser/#/R-MMU-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Mus musculus 58595 R-PFA-110133 https://reactome.org/PathwayBrowser/#/R-PFA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Plasmodium falciparum 58595 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 58595 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 58595 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 58595 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 58595 R-PFA-73788 https://reactome.org/PathwayBrowser/#/R-PFA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Plasmodium falciparum 58595 R-RNO-110133 https://reactome.org/PathwayBrowser/#/R-RNO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Rattus norvegicus 58595 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 58595 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 58595 R-RNO-73788 https://reactome.org/PathwayBrowser/#/R-RNO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Rattus norvegicus 58595 R-SCE-110133 https://reactome.org/PathwayBrowser/#/R-SCE-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Saccharomyces cerevisiae 58595 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 58595 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 58595 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 58595 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 58595 R-SCE-73788 https://reactome.org/PathwayBrowser/#/R-SCE-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Saccharomyces cerevisiae 58595 R-SPO-110133 https://reactome.org/PathwayBrowser/#/R-SPO-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Schizosaccharomyces pombe 58595 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 58595 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 58595 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 58595 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 58595 R-SPO-73788 https://reactome.org/PathwayBrowser/#/R-SPO-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Schizosaccharomyces pombe 58595 R-SSC-110133 https://reactome.org/PathwayBrowser/#/R-SSC-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Sus scrofa 58595 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 58595 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 58595 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 58595 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 58595 R-SSC-73788 https://reactome.org/PathwayBrowser/#/R-SSC-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Sus scrofa 58595 R-XTR-110133 https://reactome.org/PathwayBrowser/#/R-XTR-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Xenopus tropicalis 58595 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 58595 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 58595 R-XTR-73788 https://reactome.org/PathwayBrowser/#/R-XTR-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Xenopus tropicalis 58628 R-BTA-1855158 https://reactome.org/PathwayBrowser/#/R-BTA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Bos taurus 58628 R-BTA-1855165 https://reactome.org/PathwayBrowser/#/R-BTA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 58628 R-BTA-1855182 https://reactome.org/PathwayBrowser/#/R-BTA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Bos taurus 58628 R-BTA-1855198 https://reactome.org/PathwayBrowser/#/R-BTA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 58628 R-BTA-1855207 https://reactome.org/PathwayBrowser/#/R-BTA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Bos taurus 58628 R-BTA-1855224 https://reactome.org/PathwayBrowser/#/R-BTA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Bos taurus 58628 R-BTA-1855227 https://reactome.org/PathwayBrowser/#/R-BTA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Bos taurus 58628 R-CEL-1855158 https://reactome.org/PathwayBrowser/#/R-CEL-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 58628 R-CEL-1855165 https://reactome.org/PathwayBrowser/#/R-CEL-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 58628 R-CEL-1855182 https://reactome.org/PathwayBrowser/#/R-CEL-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Caenorhabditis elegans 58628 R-CEL-1855198 https://reactome.org/PathwayBrowser/#/R-CEL-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 58628 R-CEL-1855207 https://reactome.org/PathwayBrowser/#/R-CEL-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 58628 R-CEL-1855224 https://reactome.org/PathwayBrowser/#/R-CEL-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 58628 R-CEL-1855227 https://reactome.org/PathwayBrowser/#/R-CEL-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 58628 R-CFA-1855158 https://reactome.org/PathwayBrowser/#/R-CFA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Canis familiaris 58628 R-CFA-1855165 https://reactome.org/PathwayBrowser/#/R-CFA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 58628 R-CFA-1855182 https://reactome.org/PathwayBrowser/#/R-CFA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Canis familiaris 58628 R-CFA-1855198 https://reactome.org/PathwayBrowser/#/R-CFA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 58628 R-CFA-1855207 https://reactome.org/PathwayBrowser/#/R-CFA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Canis familiaris 58628 R-CFA-1855224 https://reactome.org/PathwayBrowser/#/R-CFA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Canis familiaris 58628 R-CFA-1855227 https://reactome.org/PathwayBrowser/#/R-CFA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Canis familiaris 58628 R-DDI-1855158 https://reactome.org/PathwayBrowser/#/R-DDI-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 58628 R-DDI-1855165 https://reactome.org/PathwayBrowser/#/R-DDI-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 58628 R-DDI-1855198 https://reactome.org/PathwayBrowser/#/R-DDI-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 58628 R-DDI-1855207 https://reactome.org/PathwayBrowser/#/R-DDI-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 58628 R-DDI-1855224 https://reactome.org/PathwayBrowser/#/R-DDI-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 58628 R-DDI-1855227 https://reactome.org/PathwayBrowser/#/R-DDI-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 58628 R-DME-1855158 https://reactome.org/PathwayBrowser/#/R-DME-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 58628 R-DME-1855165 https://reactome.org/PathwayBrowser/#/R-DME-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 58628 R-DME-1855182 https://reactome.org/PathwayBrowser/#/R-DME-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Drosophila melanogaster 58628 R-DME-1855198 https://reactome.org/PathwayBrowser/#/R-DME-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 58628 R-DME-1855207 https://reactome.org/PathwayBrowser/#/R-DME-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 58628 R-DME-1855224 https://reactome.org/PathwayBrowser/#/R-DME-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 58628 R-DME-1855227 https://reactome.org/PathwayBrowser/#/R-DME-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 58628 R-DRE-1855158 https://reactome.org/PathwayBrowser/#/R-DRE-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Danio rerio 58628 R-DRE-1855165 https://reactome.org/PathwayBrowser/#/R-DRE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 58628 R-DRE-1855198 https://reactome.org/PathwayBrowser/#/R-DRE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 58628 R-DRE-1855207 https://reactome.org/PathwayBrowser/#/R-DRE-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Danio rerio 58628 R-DRE-1855224 https://reactome.org/PathwayBrowser/#/R-DRE-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Danio rerio 58628 R-DRE-1855227 https://reactome.org/PathwayBrowser/#/R-DRE-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Danio rerio 58628 R-GGA-1855158 https://reactome.org/PathwayBrowser/#/R-GGA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Gallus gallus 58628 R-GGA-1855165 https://reactome.org/PathwayBrowser/#/R-GGA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 58628 R-GGA-1855182 https://reactome.org/PathwayBrowser/#/R-GGA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Gallus gallus 58628 R-GGA-1855198 https://reactome.org/PathwayBrowser/#/R-GGA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 58628 R-GGA-1855207 https://reactome.org/PathwayBrowser/#/R-GGA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Gallus gallus 58628 R-GGA-1855224 https://reactome.org/PathwayBrowser/#/R-GGA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Gallus gallus 58628 R-GGA-1855227 https://reactome.org/PathwayBrowser/#/R-GGA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Gallus gallus 58628 R-HSA-1855158 https://reactome.org/PathwayBrowser/#/R-HSA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol TAS Homo sapiens 58628 R-HSA-1855165 https://reactome.org/PathwayBrowser/#/R-HSA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 58628 R-HSA-1855182 https://reactome.org/PathwayBrowser/#/R-HSA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol TAS Homo sapiens 58628 R-HSA-1855198 https://reactome.org/PathwayBrowser/#/R-HSA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 58628 R-HSA-1855203 https://reactome.org/PathwayBrowser/#/R-HSA-1855203 5-PP-IP5 transports from the nucleus to the cytosol TAS Homo sapiens 58628 R-HSA-1855207 https://reactome.org/PathwayBrowser/#/R-HSA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus TAS Homo sapiens 58628 R-HSA-1855224 https://reactome.org/PathwayBrowser/#/R-HSA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus TAS Homo sapiens 58628 R-HSA-1855227 https://reactome.org/PathwayBrowser/#/R-HSA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol TAS Homo sapiens 58628 R-MMU-1855158 https://reactome.org/PathwayBrowser/#/R-MMU-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Mus musculus 58628 R-MMU-1855165 https://reactome.org/PathwayBrowser/#/R-MMU-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 58628 R-MMU-1855182 https://reactome.org/PathwayBrowser/#/R-MMU-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Mus musculus 58628 R-MMU-1855198 https://reactome.org/PathwayBrowser/#/R-MMU-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 58628 R-MMU-1855207 https://reactome.org/PathwayBrowser/#/R-MMU-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Mus musculus 58628 R-MMU-1855224 https://reactome.org/PathwayBrowser/#/R-MMU-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Mus musculus 58628 R-MMU-1855227 https://reactome.org/PathwayBrowser/#/R-MMU-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Mus musculus 58628 R-PFA-1855158 https://reactome.org/PathwayBrowser/#/R-PFA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 58628 R-PFA-1855182 https://reactome.org/PathwayBrowser/#/R-PFA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Plasmodium falciparum 58628 R-PFA-1855207 https://reactome.org/PathwayBrowser/#/R-PFA-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 58628 R-PFA-1855224 https://reactome.org/PathwayBrowser/#/R-PFA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 58628 R-PFA-1855227 https://reactome.org/PathwayBrowser/#/R-PFA-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 58628 R-RNO-1855158 https://reactome.org/PathwayBrowser/#/R-RNO-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Rattus norvegicus 58628 R-RNO-1855165 https://reactome.org/PathwayBrowser/#/R-RNO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 58628 R-RNO-1855182 https://reactome.org/PathwayBrowser/#/R-RNO-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Rattus norvegicus 58628 R-RNO-1855198 https://reactome.org/PathwayBrowser/#/R-RNO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 58628 R-RNO-1855207 https://reactome.org/PathwayBrowser/#/R-RNO-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Rattus norvegicus 58628 R-RNO-1855224 https://reactome.org/PathwayBrowser/#/R-RNO-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Rattus norvegicus 58628 R-RNO-1855227 https://reactome.org/PathwayBrowser/#/R-RNO-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Rattus norvegicus 58628 R-SCE-1855158 https://reactome.org/PathwayBrowser/#/R-SCE-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 58628 R-SCE-1855165 https://reactome.org/PathwayBrowser/#/R-SCE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 58628 R-SCE-1855182 https://reactome.org/PathwayBrowser/#/R-SCE-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Saccharomyces cerevisiae 58628 R-SCE-1855198 https://reactome.org/PathwayBrowser/#/R-SCE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 58628 R-SCE-1855207 https://reactome.org/PathwayBrowser/#/R-SCE-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 58628 R-SCE-1855224 https://reactome.org/PathwayBrowser/#/R-SCE-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 58628 R-SCE-1855227 https://reactome.org/PathwayBrowser/#/R-SCE-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 58628 R-SPO-1855158 https://reactome.org/PathwayBrowser/#/R-SPO-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 58628 R-SPO-1855165 https://reactome.org/PathwayBrowser/#/R-SPO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 58628 R-SPO-1855182 https://reactome.org/PathwayBrowser/#/R-SPO-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Schizosaccharomyces pombe 58628 R-SPO-1855198 https://reactome.org/PathwayBrowser/#/R-SPO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 58628 R-SPO-1855207 https://reactome.org/PathwayBrowser/#/R-SPO-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 58628 R-SPO-1855224 https://reactome.org/PathwayBrowser/#/R-SPO-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 58628 R-SPO-1855227 https://reactome.org/PathwayBrowser/#/R-SPO-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 58628 R-SSC-1855158 https://reactome.org/PathwayBrowser/#/R-SSC-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Sus scrofa 58628 R-SSC-1855165 https://reactome.org/PathwayBrowser/#/R-SSC-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 58628 R-SSC-1855182 https://reactome.org/PathwayBrowser/#/R-SSC-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Sus scrofa 58628 R-SSC-1855198 https://reactome.org/PathwayBrowser/#/R-SSC-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 58628 R-SSC-1855207 https://reactome.org/PathwayBrowser/#/R-SSC-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Sus scrofa 58628 R-SSC-1855224 https://reactome.org/PathwayBrowser/#/R-SSC-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Sus scrofa 58628 R-SSC-1855227 https://reactome.org/PathwayBrowser/#/R-SSC-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Sus scrofa 58628 R-XTR-1855158 https://reactome.org/PathwayBrowser/#/R-XTR-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 58628 R-XTR-1855165 https://reactome.org/PathwayBrowser/#/R-XTR-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 58628 R-XTR-1855182 https://reactome.org/PathwayBrowser/#/R-XTR-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Xenopus tropicalis 58628 R-XTR-1855198 https://reactome.org/PathwayBrowser/#/R-XTR-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 58628 R-XTR-1855207 https://reactome.org/PathwayBrowser/#/R-XTR-1855207 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 58628 R-XTR-1855224 https://reactome.org/PathwayBrowser/#/R-XTR-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 58628 R-XTR-1855227 https://reactome.org/PathwayBrowser/#/R-XTR-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 58672 R-BTA-508561 https://reactome.org/PathwayBrowser/#/R-BTA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Bos taurus 58672 R-BTA-70941 https://reactome.org/PathwayBrowser/#/R-BTA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Bos taurus 58672 R-BTA-70952 https://reactome.org/PathwayBrowser/#/R-BTA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Bos taurus 58672 R-CEL-70941 https://reactome.org/PathwayBrowser/#/R-CEL-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Caenorhabditis elegans 58672 R-CFA-508561 https://reactome.org/PathwayBrowser/#/R-CFA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Canis familiaris 58672 R-CFA-70941 https://reactome.org/PathwayBrowser/#/R-CFA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Canis familiaris 58672 R-CFA-70952 https://reactome.org/PathwayBrowser/#/R-CFA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Canis familiaris 58672 R-DDI-508561 https://reactome.org/PathwayBrowser/#/R-DDI-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Dictyostelium discoideum 58672 R-DDI-70941 https://reactome.org/PathwayBrowser/#/R-DDI-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Dictyostelium discoideum 58672 R-DDI-70952 https://reactome.org/PathwayBrowser/#/R-DDI-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Dictyostelium discoideum 58672 R-DME-70941 https://reactome.org/PathwayBrowser/#/R-DME-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Drosophila melanogaster 58672 R-DRE-70941 https://reactome.org/PathwayBrowser/#/R-DRE-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Danio rerio 58672 R-GGA-508561 https://reactome.org/PathwayBrowser/#/R-GGA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Gallus gallus 58672 R-GGA-70941 https://reactome.org/PathwayBrowser/#/R-GGA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Gallus gallus 58672 R-GGA-70952 https://reactome.org/PathwayBrowser/#/R-GGA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Gallus gallus 58672 R-HSA-508561 https://reactome.org/PathwayBrowser/#/R-HSA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate TAS Homo sapiens 58672 R-HSA-70941 https://reactome.org/PathwayBrowser/#/R-HSA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ TAS Homo sapiens 58672 R-HSA-70952 https://reactome.org/PathwayBrowser/#/R-HSA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate TAS Homo sapiens 58672 R-MMU-508561 https://reactome.org/PathwayBrowser/#/R-MMU-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Mus musculus 58672 R-MMU-70941 https://reactome.org/PathwayBrowser/#/R-MMU-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Mus musculus 58672 R-MMU-70952 https://reactome.org/PathwayBrowser/#/R-MMU-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Mus musculus 58672 R-RNO-508561 https://reactome.org/PathwayBrowser/#/R-RNO-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Rattus norvegicus 58672 R-RNO-70941 https://reactome.org/PathwayBrowser/#/R-RNO-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Rattus norvegicus 58672 R-RNO-70952 https://reactome.org/PathwayBrowser/#/R-RNO-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Rattus norvegicus 58672 R-SCE-508561 https://reactome.org/PathwayBrowser/#/R-SCE-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Saccharomyces cerevisiae 58672 R-SCE-70952 https://reactome.org/PathwayBrowser/#/R-SCE-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Saccharomyces cerevisiae 58672 R-SPO-508561 https://reactome.org/PathwayBrowser/#/R-SPO-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Schizosaccharomyces pombe 58672 R-SPO-70952 https://reactome.org/PathwayBrowser/#/R-SPO-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Schizosaccharomyces pombe 58672 R-SSC-508561 https://reactome.org/PathwayBrowser/#/R-SSC-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Sus scrofa 58672 R-SSC-70941 https://reactome.org/PathwayBrowser/#/R-SSC-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Sus scrofa 58672 R-SSC-70952 https://reactome.org/PathwayBrowser/#/R-SSC-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Sus scrofa 58672 R-XTR-508561 https://reactome.org/PathwayBrowser/#/R-XTR-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Xenopus tropicalis 58672 R-XTR-70941 https://reactome.org/PathwayBrowser/#/R-XTR-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Xenopus tropicalis 58672 R-XTR-70952 https://reactome.org/PathwayBrowser/#/R-XTR-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Xenopus tropicalis 58681 R-BTA-73814 https://reactome.org/PathwayBrowser/#/R-BTA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Bos taurus 58681 R-BTA-73815 https://reactome.org/PathwayBrowser/#/R-BTA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Bos taurus 58681 R-CEL-73814 https://reactome.org/PathwayBrowser/#/R-CEL-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Caenorhabditis elegans 58681 R-CEL-73815 https://reactome.org/PathwayBrowser/#/R-CEL-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Caenorhabditis elegans 58681 R-CFA-73814 https://reactome.org/PathwayBrowser/#/R-CFA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Canis familiaris 58681 R-CFA-73815 https://reactome.org/PathwayBrowser/#/R-CFA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Canis familiaris 58681 R-DDI-73814 https://reactome.org/PathwayBrowser/#/R-DDI-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Dictyostelium discoideum 58681 R-DME-73814 https://reactome.org/PathwayBrowser/#/R-DME-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Drosophila melanogaster 58681 R-DME-73815 https://reactome.org/PathwayBrowser/#/R-DME-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Drosophila melanogaster 58681 R-DRE-73814 https://reactome.org/PathwayBrowser/#/R-DRE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Danio rerio 58681 R-DRE-73815 https://reactome.org/PathwayBrowser/#/R-DRE-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Danio rerio 58681 R-GGA-419152 https://reactome.org/PathwayBrowser/#/R-GGA-419152 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate TAS Gallus gallus 58681 R-GGA-419153 https://reactome.org/PathwayBrowser/#/R-GGA-419153 5-phosphoribosylamine + glycine + ATP <=> 5-phosphoribosylglycinamide (GAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 58681 R-GGA-73814 https://reactome.org/PathwayBrowser/#/R-GGA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Gallus gallus 58681 R-GGA-73815 https://reactome.org/PathwayBrowser/#/R-GGA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Gallus gallus 58681 R-HSA-73814 https://reactome.org/PathwayBrowser/#/R-HSA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi TAS Homo sapiens 58681 R-HSA-73815 https://reactome.org/PathwayBrowser/#/R-HSA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate TAS Homo sapiens 58681 R-MMU-73814 https://reactome.org/PathwayBrowser/#/R-MMU-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Mus musculus 58681 R-MMU-73815 https://reactome.org/PathwayBrowser/#/R-MMU-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Mus musculus 58681 R-RNO-73814 https://reactome.org/PathwayBrowser/#/R-RNO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Rattus norvegicus 58681 R-RNO-73815 https://reactome.org/PathwayBrowser/#/R-RNO-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Rattus norvegicus 58681 R-SCE-73814 https://reactome.org/PathwayBrowser/#/R-SCE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Saccharomyces cerevisiae 58681 R-SPO-73814 https://reactome.org/PathwayBrowser/#/R-SPO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Schizosaccharomyces pombe 58681 R-SSC-73814 https://reactome.org/PathwayBrowser/#/R-SSC-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Sus scrofa 58681 R-SSC-73815 https://reactome.org/PathwayBrowser/#/R-SSC-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Sus scrofa 58681 R-XTR-73814 https://reactome.org/PathwayBrowser/#/R-XTR-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Xenopus tropicalis 58681 R-XTR-73815 https://reactome.org/PathwayBrowser/#/R-XTR-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Xenopus tropicalis 58698 R-BTA-947531 https://reactome.org/PathwayBrowser/#/R-BTA-947531 Molybdenum ion transfer onto molybdopterin IEA Bos taurus 58698 R-CEL-947531 https://reactome.org/PathwayBrowser/#/R-CEL-947531 Molybdenum ion transfer onto molybdopterin IEA Caenorhabditis elegans 58698 R-CFA-947531 https://reactome.org/PathwayBrowser/#/R-CFA-947531 Molybdenum ion transfer onto molybdopterin IEA Canis familiaris 58698 R-DDI-947531 https://reactome.org/PathwayBrowser/#/R-DDI-947531 Molybdenum ion transfer onto molybdopterin IEA Dictyostelium discoideum 58698 R-DME-947531 https://reactome.org/PathwayBrowser/#/R-DME-947531 Molybdenum ion transfer onto molybdopterin IEA Drosophila melanogaster 58698 R-GGA-947531 https://reactome.org/PathwayBrowser/#/R-GGA-947531 Molybdenum ion transfer onto molybdopterin IEA Gallus gallus 58698 R-HSA-947531 https://reactome.org/PathwayBrowser/#/R-HSA-947531 Molybdenum ion transfer onto molybdopterin TAS Homo sapiens 58698 R-HSA-947541 https://reactome.org/PathwayBrowser/#/R-HSA-947541 Sulfhydrylation and ring cleavage of precursor Z TAS Homo sapiens 58698 R-MMU-947531 https://reactome.org/PathwayBrowser/#/R-MMU-947531 Molybdenum ion transfer onto molybdopterin IEA Mus musculus 58698 R-RNO-947531 https://reactome.org/PathwayBrowser/#/R-RNO-947531 Molybdenum ion transfer onto molybdopterin IEA Rattus norvegicus 58698 R-SSC-947531 https://reactome.org/PathwayBrowser/#/R-SSC-947531 Molybdenum ion transfer onto molybdopterin IEA Sus scrofa 58702 R-BTA-372449 https://reactome.org/PathwayBrowser/#/R-BTA-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Bos taurus 58702 R-BTA-372819 https://reactome.org/PathwayBrowser/#/R-BTA-372819 PCK2 phosphorylates OA to yield PEP IEA Bos taurus 58702 R-BTA-4084976 https://reactome.org/PathwayBrowser/#/R-BTA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Bos taurus 58702 R-BTA-70241 https://reactome.org/PathwayBrowser/#/R-BTA-70241 PCK1 phosphorylates OA to yield PEP IEA Bos taurus 58702 R-BTA-70494 https://reactome.org/PathwayBrowser/#/R-BTA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Bos taurus 58702 R-BTA-71660 https://reactome.org/PathwayBrowser/#/R-BTA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Bos taurus 58702 R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 58702 R-CEL-372449 https://reactome.org/PathwayBrowser/#/R-CEL-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Caenorhabditis elegans 58702 R-CEL-372819 https://reactome.org/PathwayBrowser/#/R-CEL-372819 PCK2 phosphorylates OA to yield PEP IEA Caenorhabditis elegans 58702 R-CEL-70241 https://reactome.org/PathwayBrowser/#/R-CEL-70241 PCK1 phosphorylates OA to yield PEP IEA Caenorhabditis elegans 58702 R-CEL-70494 https://reactome.org/PathwayBrowser/#/R-CEL-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Caenorhabditis elegans 58702 R-CEL-71660 https://reactome.org/PathwayBrowser/#/R-CEL-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Caenorhabditis elegans 58702 R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 58702 R-CFA-372449 https://reactome.org/PathwayBrowser/#/R-CFA-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Canis familiaris 58702 R-CFA-372819 https://reactome.org/PathwayBrowser/#/R-CFA-372819 PCK2 phosphorylates OA to yield PEP IEA Canis familiaris 58702 R-CFA-4084976 https://reactome.org/PathwayBrowser/#/R-CFA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Canis familiaris 58702 R-CFA-70241 https://reactome.org/PathwayBrowser/#/R-CFA-70241 PCK1 phosphorylates OA to yield PEP IEA Canis familiaris 58702 R-CFA-70494 https://reactome.org/PathwayBrowser/#/R-CFA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Canis familiaris 58702 R-CFA-71660 https://reactome.org/PathwayBrowser/#/R-CFA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Canis familiaris 58702 R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 58702 R-DDI-372819 https://reactome.org/PathwayBrowser/#/R-DDI-372819 PCK2 phosphorylates OA to yield PEP IEA Dictyostelium discoideum 58702 R-DDI-70241 https://reactome.org/PathwayBrowser/#/R-DDI-70241 PCK1 phosphorylates OA to yield PEP IEA Dictyostelium discoideum 58702 R-DDI-70494 https://reactome.org/PathwayBrowser/#/R-DDI-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Dictyostelium discoideum 58702 R-DDI-71660 https://reactome.org/PathwayBrowser/#/R-DDI-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Dictyostelium discoideum 58702 R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 58702 R-DME-372449 https://reactome.org/PathwayBrowser/#/R-DME-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Drosophila melanogaster 58702 R-DME-372819 https://reactome.org/PathwayBrowser/#/R-DME-372819 PCK2 phosphorylates OA to yield PEP IEA Drosophila melanogaster 58702 R-DME-4084976 https://reactome.org/PathwayBrowser/#/R-DME-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Drosophila melanogaster 58702 R-DME-70241 https://reactome.org/PathwayBrowser/#/R-DME-70241 PCK1 phosphorylates OA to yield PEP IEA Drosophila melanogaster 58702 R-DME-70494 https://reactome.org/PathwayBrowser/#/R-DME-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Drosophila melanogaster 58702 R-DME-71660 https://reactome.org/PathwayBrowser/#/R-DME-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Drosophila melanogaster 58702 R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 58702 R-DRE-372449 https://reactome.org/PathwayBrowser/#/R-DRE-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Danio rerio 58702 R-DRE-372819 https://reactome.org/PathwayBrowser/#/R-DRE-372819 PCK2 phosphorylates OA to yield PEP IEA Danio rerio 58702 R-DRE-4084976 https://reactome.org/PathwayBrowser/#/R-DRE-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Danio rerio 58702 R-DRE-70241 https://reactome.org/PathwayBrowser/#/R-DRE-70241 PCK1 phosphorylates OA to yield PEP IEA Danio rerio 58702 R-DRE-70494 https://reactome.org/PathwayBrowser/#/R-DRE-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Danio rerio 58702 R-DRE-71660 https://reactome.org/PathwayBrowser/#/R-DRE-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Danio rerio 58702 R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 58702 R-GGA-352981 https://reactome.org/PathwayBrowser/#/R-GGA-352981 phosphoenolpyruvate + H2O <=> 2-phosphoglycerate TAS Gallus gallus 58702 R-GGA-353044 https://reactome.org/PathwayBrowser/#/R-GGA-353044 2-phosphoglycerate <=> phosphoenolpyruvate + H2O TAS Gallus gallus 58702 R-GGA-353056 https://reactome.org/PathwayBrowser/#/R-GGA-353056 phosphoenolpyruvate + ADP => pyruvate + ATP TAS Gallus gallus 58702 R-GGA-372449 https://reactome.org/PathwayBrowser/#/R-GGA-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Gallus gallus 58702 R-GGA-372723 https://reactome.org/PathwayBrowser/#/R-GGA-372723 phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] <=> phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix] IEA Gallus gallus 58702 R-GGA-372724 https://reactome.org/PathwayBrowser/#/R-GGA-372724 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] TAS Gallus gallus 58702 R-GGA-372741 https://reactome.org/PathwayBrowser/#/R-GGA-372741 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] TAS Gallus gallus 58702 R-GGA-372819 https://reactome.org/PathwayBrowser/#/R-GGA-372819 PCK2 phosphorylates OA to yield PEP IEA Gallus gallus 58702 R-GGA-4084976 https://reactome.org/PathwayBrowser/#/R-GGA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Gallus gallus 58702 R-GGA-70241 https://reactome.org/PathwayBrowser/#/R-GGA-70241 PCK1 phosphorylates OA to yield PEP IEA Gallus gallus 58702 R-GGA-70494 https://reactome.org/PathwayBrowser/#/R-GGA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Gallus gallus 58702 R-GGA-71660 https://reactome.org/PathwayBrowser/#/R-GGA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Gallus gallus 58702 R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 58702 R-HSA-372449 https://reactome.org/PathwayBrowser/#/R-HSA-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion TAS Homo sapiens 58702 R-HSA-372819 https://reactome.org/PathwayBrowser/#/R-HSA-372819 PCK2 phosphorylates OA to yield PEP TAS Homo sapiens 58702 R-HSA-4084976 https://reactome.org/PathwayBrowser/#/R-HSA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P TAS Homo sapiens 58702 R-HSA-70241 https://reactome.org/PathwayBrowser/#/R-HSA-70241 PCK1 phosphorylates OA to yield PEP TAS Homo sapiens 58702 R-HSA-70494 https://reactome.org/PathwayBrowser/#/R-HSA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG TAS Homo sapiens 58702 R-HSA-71660 https://reactome.org/PathwayBrowser/#/R-HSA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O TAS Homo sapiens 58702 R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 58702 R-MMU-372449 https://reactome.org/PathwayBrowser/#/R-MMU-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Mus musculus 58702 R-MMU-372819 https://reactome.org/PathwayBrowser/#/R-MMU-372819 PCK2 phosphorylates OA to yield PEP IEA Mus musculus 58702 R-MMU-4084976 https://reactome.org/PathwayBrowser/#/R-MMU-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Mus musculus 58702 R-MMU-70241 https://reactome.org/PathwayBrowser/#/R-MMU-70241 PCK1 phosphorylates OA to yield PEP IEA Mus musculus 58702 R-MMU-70494 https://reactome.org/PathwayBrowser/#/R-MMU-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Mus musculus 58702 R-MMU-71660 https://reactome.org/PathwayBrowser/#/R-MMU-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Mus musculus 58702 R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 58702 R-MTU-964886 https://reactome.org/PathwayBrowser/#/R-MTU-964886 EPSP from shikimate 3-phosphate TAS Mycobacterium tuberculosis 58702 R-MTU-964912 https://reactome.org/PathwayBrowser/#/R-MTU-964912 DHAP from Ery4P and PEP TAS Mycobacterium tuberculosis 58702 R-PFA-70494 https://reactome.org/PathwayBrowser/#/R-PFA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Plasmodium falciparum 58702 R-PFA-71660 https://reactome.org/PathwayBrowser/#/R-PFA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Plasmodium falciparum 58702 R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 58702 R-RNO-372449 https://reactome.org/PathwayBrowser/#/R-RNO-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Rattus norvegicus 58702 R-RNO-372819 https://reactome.org/PathwayBrowser/#/R-RNO-372819 PCK2 phosphorylates OA to yield PEP IEA Rattus norvegicus 58702 R-RNO-4084976 https://reactome.org/PathwayBrowser/#/R-RNO-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Rattus norvegicus 58702 R-RNO-70241 https://reactome.org/PathwayBrowser/#/R-RNO-70241 PCK1 phosphorylates OA to yield PEP IEA Rattus norvegicus 58702 R-RNO-70494 https://reactome.org/PathwayBrowser/#/R-RNO-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Rattus norvegicus 58702 R-RNO-71660 https://reactome.org/PathwayBrowser/#/R-RNO-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Rattus norvegicus 58702 R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 58702 R-SCE-372449 https://reactome.org/PathwayBrowser/#/R-SCE-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Saccharomyces cerevisiae 58702 R-SCE-70494 https://reactome.org/PathwayBrowser/#/R-SCE-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Saccharomyces cerevisiae 58702 R-SCE-71660 https://reactome.org/PathwayBrowser/#/R-SCE-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Saccharomyces cerevisiae 58702 R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 58702 R-SPO-372449 https://reactome.org/PathwayBrowser/#/R-SPO-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Schizosaccharomyces pombe 58702 R-SPO-70494 https://reactome.org/PathwayBrowser/#/R-SPO-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Schizosaccharomyces pombe 58702 R-SPO-71660 https://reactome.org/PathwayBrowser/#/R-SPO-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Schizosaccharomyces pombe 58702 R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 58702 R-SSC-372449 https://reactome.org/PathwayBrowser/#/R-SSC-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Sus scrofa 58702 R-SSC-372819 https://reactome.org/PathwayBrowser/#/R-SSC-372819 PCK2 phosphorylates OA to yield PEP IEA Sus scrofa 58702 R-SSC-4084976 https://reactome.org/PathwayBrowser/#/R-SSC-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Sus scrofa 58702 R-SSC-70241 https://reactome.org/PathwayBrowser/#/R-SSC-70241 PCK1 phosphorylates OA to yield PEP IEA Sus scrofa 58702 R-SSC-70494 https://reactome.org/PathwayBrowser/#/R-SSC-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Sus scrofa 58702 R-SSC-71660 https://reactome.org/PathwayBrowser/#/R-SSC-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Sus scrofa 58702 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 58702 R-XTR-372449 https://reactome.org/PathwayBrowser/#/R-XTR-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Xenopus tropicalis 58702 R-XTR-4084976 https://reactome.org/PathwayBrowser/#/R-XTR-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Xenopus tropicalis 58702 R-XTR-70241 https://reactome.org/PathwayBrowser/#/R-XTR-70241 PCK1 phosphorylates OA to yield PEP IEA Xenopus tropicalis 58702 R-XTR-70494 https://reactome.org/PathwayBrowser/#/R-XTR-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Xenopus tropicalis 58702 R-XTR-71660 https://reactome.org/PathwayBrowser/#/R-XTR-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O IEA Xenopus tropicalis 58702 R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 58758 R-BTA-5692237 https://reactome.org/PathwayBrowser/#/R-BTA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Bos taurus 58758 R-CEL-5692237 https://reactome.org/PathwayBrowser/#/R-CEL-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Caenorhabditis elegans 58758 R-CFA-5692237 https://reactome.org/PathwayBrowser/#/R-CFA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Canis familiaris 58758 R-DDI-5692237 https://reactome.org/PathwayBrowser/#/R-DDI-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Dictyostelium discoideum 58758 R-DME-5692237 https://reactome.org/PathwayBrowser/#/R-DME-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Drosophila melanogaster 58758 R-DRE-5692237 https://reactome.org/PathwayBrowser/#/R-DRE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Danio rerio 58758 R-GGA-5692237 https://reactome.org/PathwayBrowser/#/R-GGA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Gallus gallus 58758 R-HSA-5692237 https://reactome.org/PathwayBrowser/#/R-HSA-5692237 ADH5 oxidises S-HMGSH to S-FGSH TAS Homo sapiens 58758 R-MMU-5692237 https://reactome.org/PathwayBrowser/#/R-MMU-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Mus musculus 58758 R-RNO-5692237 https://reactome.org/PathwayBrowser/#/R-RNO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Rattus norvegicus 58758 R-SCE-5692237 https://reactome.org/PathwayBrowser/#/R-SCE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Saccharomyces cerevisiae 58758 R-SPO-5692237 https://reactome.org/PathwayBrowser/#/R-SPO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Schizosaccharomyces pombe 58758 R-SSC-5692237 https://reactome.org/PathwayBrowser/#/R-SSC-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Sus scrofa 58758 R-XTR-5692237 https://reactome.org/PathwayBrowser/#/R-XTR-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Xenopus tropicalis 58759 R-BTA-71296 https://reactome.org/PathwayBrowser/#/R-BTA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Bos taurus 58759 R-BTA-71299 https://reactome.org/PathwayBrowser/#/R-BTA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Bos taurus 58759 R-CEL-71296 https://reactome.org/PathwayBrowser/#/R-CEL-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Caenorhabditis elegans 58759 R-CEL-71299 https://reactome.org/PathwayBrowser/#/R-CEL-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 58759 R-CFA-71296 https://reactome.org/PathwayBrowser/#/R-CFA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Canis familiaris 58759 R-CFA-71299 https://reactome.org/PathwayBrowser/#/R-CFA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Canis familiaris 58759 R-DDI-71296 https://reactome.org/PathwayBrowser/#/R-DDI-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Dictyostelium discoideum 58759 R-DDI-71299 https://reactome.org/PathwayBrowser/#/R-DDI-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 58759 R-DME-71296 https://reactome.org/PathwayBrowser/#/R-DME-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Drosophila melanogaster 58759 R-DME-71299 https://reactome.org/PathwayBrowser/#/R-DME-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Drosophila melanogaster 58759 R-DRE-71299 https://reactome.org/PathwayBrowser/#/R-DRE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Danio rerio 58759 R-GGA-71296 https://reactome.org/PathwayBrowser/#/R-GGA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Gallus gallus 58759 R-GGA-71299 https://reactome.org/PathwayBrowser/#/R-GGA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Gallus gallus 58759 R-HSA-71296 https://reactome.org/PathwayBrowser/#/R-HSA-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate TAS Homo sapiens 58759 R-HSA-71299 https://reactome.org/PathwayBrowser/#/R-HSA-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ TAS Homo sapiens 58759 R-MMU-71296 https://reactome.org/PathwayBrowser/#/R-MMU-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Mus musculus 58759 R-MMU-71299 https://reactome.org/PathwayBrowser/#/R-MMU-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Mus musculus 58759 R-RNO-71296 https://reactome.org/PathwayBrowser/#/R-RNO-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Rattus norvegicus 58759 R-RNO-71299 https://reactome.org/PathwayBrowser/#/R-RNO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Rattus norvegicus 58759 R-SCE-71296 https://reactome.org/PathwayBrowser/#/R-SCE-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Saccharomyces cerevisiae 58759 R-SCE-71299 https://reactome.org/PathwayBrowser/#/R-SCE-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 58759 R-SPO-71296 https://reactome.org/PathwayBrowser/#/R-SPO-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Schizosaccharomyces pombe 58759 R-SPO-71299 https://reactome.org/PathwayBrowser/#/R-SPO-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 58759 R-SSC-71296 https://reactome.org/PathwayBrowser/#/R-SSC-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Sus scrofa 58759 R-SSC-71299 https://reactome.org/PathwayBrowser/#/R-SSC-71299 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ IEA Sus scrofa 58759 R-XTR-71296 https://reactome.org/PathwayBrowser/#/R-XTR-71296 D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate IEA Xenopus tropicalis 58769 R-BTA-6783880 https://reactome.org/PathwayBrowser/#/R-BTA-6783880 PIPOX oxidises PPCA to P6C IEA Bos taurus 58769 R-CEL-6783880 https://reactome.org/PathwayBrowser/#/R-CEL-6783880 PIPOX oxidises PPCA to P6C IEA Caenorhabditis elegans 58769 R-CFA-6783880 https://reactome.org/PathwayBrowser/#/R-CFA-6783880 PIPOX oxidises PPCA to P6C IEA Canis familiaris 58769 R-DDI-6783880 https://reactome.org/PathwayBrowser/#/R-DDI-6783880 PIPOX oxidises PPCA to P6C IEA Dictyostelium discoideum 58769 R-GGA-6783880 https://reactome.org/PathwayBrowser/#/R-GGA-6783880 PIPOX oxidises PPCA to P6C IEA Gallus gallus 58769 R-HSA-6783880 https://reactome.org/PathwayBrowser/#/R-HSA-6783880 PIPOX oxidises PPCA to P6C TAS Homo sapiens 58769 R-HSA-6783883 https://reactome.org/PathwayBrowser/#/R-HSA-6783883 P6C transforms to 2AMAS TAS Homo sapiens 58769 R-MMU-6783880 https://reactome.org/PathwayBrowser/#/R-MMU-6783880 PIPOX oxidises PPCA to P6C IEA Mus musculus 58769 R-RNO-6783880 https://reactome.org/PathwayBrowser/#/R-RNO-6783880 PIPOX oxidises PPCA to P6C IEA Rattus norvegicus 58769 R-SPO-6783880 https://reactome.org/PathwayBrowser/#/R-SPO-6783880 PIPOX oxidises PPCA to P6C IEA Schizosaccharomyces pombe 58769 R-SSC-6783880 https://reactome.org/PathwayBrowser/#/R-SSC-6783880 PIPOX oxidises PPCA to P6C IEA Sus scrofa 58769 R-XTR-6783880 https://reactome.org/PathwayBrowser/#/R-XTR-6783880 PIPOX oxidises PPCA to P6C IEA Xenopus tropicalis 58795 R-BTA-1237119 https://reactome.org/PathwayBrowser/#/R-BTA-1237119 Acireductone is oxidized to MOB IEA Bos taurus 58795 R-BTA-1237129 https://reactome.org/PathwayBrowser/#/R-BTA-1237129 Acireductone is created IEA Bos taurus 58795 R-CEL-1237119 https://reactome.org/PathwayBrowser/#/R-CEL-1237119 Acireductone is oxidized to MOB IEA Caenorhabditis elegans 58795 R-CEL-1237129 https://reactome.org/PathwayBrowser/#/R-CEL-1237129 Acireductone is created IEA Caenorhabditis elegans 58795 R-CFA-1237119 https://reactome.org/PathwayBrowser/#/R-CFA-1237119 Acireductone is oxidized to MOB IEA Canis familiaris 58795 R-CFA-1237129 https://reactome.org/PathwayBrowser/#/R-CFA-1237129 Acireductone is created IEA Canis familiaris 58795 R-DDI-1237119 https://reactome.org/PathwayBrowser/#/R-DDI-1237119 Acireductone is oxidized to MOB IEA Dictyostelium discoideum 58795 R-DDI-1237129 https://reactome.org/PathwayBrowser/#/R-DDI-1237129 Acireductone is created IEA Dictyostelium discoideum 58795 R-DME-1237119 https://reactome.org/PathwayBrowser/#/R-DME-1237119 Acireductone is oxidized to MOB IEA Drosophila melanogaster 58795 R-DME-1237129 https://reactome.org/PathwayBrowser/#/R-DME-1237129 Acireductone is created IEA Drosophila melanogaster 58795 R-DRE-1237119 https://reactome.org/PathwayBrowser/#/R-DRE-1237119 Acireductone is oxidized to MOB IEA Danio rerio 58795 R-DRE-1237129 https://reactome.org/PathwayBrowser/#/R-DRE-1237129 Acireductone is created IEA Danio rerio 58795 R-GGA-1237119 https://reactome.org/PathwayBrowser/#/R-GGA-1237119 Acireductone is oxidized to MOB IEA Gallus gallus 58795 R-GGA-1237129 https://reactome.org/PathwayBrowser/#/R-GGA-1237129 Acireductone is created IEA Gallus gallus 58795 R-HSA-1237119 https://reactome.org/PathwayBrowser/#/R-HSA-1237119 Acireductone is oxidized to MOB TAS Homo sapiens 58795 R-HSA-1237129 https://reactome.org/PathwayBrowser/#/R-HSA-1237129 Acireductone is created TAS Homo sapiens 58795 R-MMU-1237119 https://reactome.org/PathwayBrowser/#/R-MMU-1237119 Acireductone is oxidized to MOB IEA Mus musculus 58795 R-MMU-1237129 https://reactome.org/PathwayBrowser/#/R-MMU-1237129 Acireductone is created IEA Mus musculus 58795 R-RNO-1237119 https://reactome.org/PathwayBrowser/#/R-RNO-1237119 Acireductone is oxidized to MOB IEA Rattus norvegicus 58795 R-RNO-1237129 https://reactome.org/PathwayBrowser/#/R-RNO-1237129 Acireductone is created IEA Rattus norvegicus 58795 R-SCE-1237119 https://reactome.org/PathwayBrowser/#/R-SCE-1237119 Acireductone is oxidized to MOB IEA Saccharomyces cerevisiae 58795 R-SCE-1237129 https://reactome.org/PathwayBrowser/#/R-SCE-1237129 Acireductone is created IEA Saccharomyces cerevisiae 58795 R-SPO-1237119 https://reactome.org/PathwayBrowser/#/R-SPO-1237119 Acireductone is oxidized to MOB IEA Schizosaccharomyces pombe 58795 R-SPO-1237129 https://reactome.org/PathwayBrowser/#/R-SPO-1237129 Acireductone is created IEA Schizosaccharomyces pombe 58795 R-SSC-1237119 https://reactome.org/PathwayBrowser/#/R-SSC-1237119 Acireductone is oxidized to MOB IEA Sus scrofa 58795 R-SSC-1237129 https://reactome.org/PathwayBrowser/#/R-SSC-1237129 Acireductone is created IEA Sus scrofa 58795 R-XTR-1237119 https://reactome.org/PathwayBrowser/#/R-XTR-1237119 Acireductone is oxidized to MOB IEA Xenopus tropicalis 58795 R-XTR-1237129 https://reactome.org/PathwayBrowser/#/R-XTR-1237129 Acireductone is created IEA Xenopus tropicalis 58828 R-BTA-1237129 https://reactome.org/PathwayBrowser/#/R-BTA-1237129 Acireductone is created IEA Bos taurus 58828 R-CEL-1237129 https://reactome.org/PathwayBrowser/#/R-CEL-1237129 Acireductone is created IEA Caenorhabditis elegans 58828 R-CFA-1237129 https://reactome.org/PathwayBrowser/#/R-CFA-1237129 Acireductone is created IEA Canis familiaris 58828 R-DDI-1237129 https://reactome.org/PathwayBrowser/#/R-DDI-1237129 Acireductone is created IEA Dictyostelium discoideum 58828 R-DME-1237129 https://reactome.org/PathwayBrowser/#/R-DME-1237129 Acireductone is created IEA Drosophila melanogaster 58828 R-DRE-1237129 https://reactome.org/PathwayBrowser/#/R-DRE-1237129 Acireductone is created IEA Danio rerio 58828 R-GGA-1237129 https://reactome.org/PathwayBrowser/#/R-GGA-1237129 Acireductone is created IEA Gallus gallus 58828 R-HSA-1237129 https://reactome.org/PathwayBrowser/#/R-HSA-1237129 Acireductone is created TAS Homo sapiens 58828 R-HSA-1237140 https://reactome.org/PathwayBrowser/#/R-HSA-1237140 Dehydration of methylthio-ribulose-P IEA Homo sapiens 58828 R-MMU-1237129 https://reactome.org/PathwayBrowser/#/R-MMU-1237129 Acireductone is created IEA Mus musculus 58828 R-RNO-1237129 https://reactome.org/PathwayBrowser/#/R-RNO-1237129 Acireductone is created IEA Rattus norvegicus 58828 R-SCE-1237121 https://reactome.org/PathwayBrowser/#/R-SCE-1237121 Dehydration of methylthio-ribulose-P TAS Saccharomyces cerevisiae 58828 R-SCE-1237129 https://reactome.org/PathwayBrowser/#/R-SCE-1237129 Acireductone is created IEA Saccharomyces cerevisiae 58828 R-SPO-1237129 https://reactome.org/PathwayBrowser/#/R-SPO-1237129 Acireductone is created IEA Schizosaccharomyces pombe 58828 R-SSC-1237129 https://reactome.org/PathwayBrowser/#/R-SSC-1237129 Acireductone is created IEA Sus scrofa 58828 R-XTR-1237129 https://reactome.org/PathwayBrowser/#/R-XTR-1237129 Acireductone is created IEA Xenopus tropicalis 58856 R-BTA-6809810 https://reactome.org/PathwayBrowser/#/R-BTA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Bos taurus 58856 R-CFA-6809810 https://reactome.org/PathwayBrowser/#/R-CFA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Canis familiaris 58856 R-DRE-6809810 https://reactome.org/PathwayBrowser/#/R-DRE-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Danio rerio 58856 R-GGA-6809810 https://reactome.org/PathwayBrowser/#/R-GGA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Gallus gallus 58856 R-HSA-6809810 https://reactome.org/PathwayBrowser/#/R-HSA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA TAS Homo sapiens 58856 R-MMU-6809810 https://reactome.org/PathwayBrowser/#/R-MMU-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Mus musculus 58856 R-RNO-6809810 https://reactome.org/PathwayBrowser/#/R-RNO-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Rattus norvegicus 58856 R-SSC-6809810 https://reactome.org/PathwayBrowser/#/R-SSC-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Sus scrofa 58937 R-BTA-163741 https://reactome.org/PathwayBrowser/#/R-BTA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Bos taurus 58937 R-BTA-163751 https://reactome.org/PathwayBrowser/#/R-BTA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Bos taurus 58937 R-BTA-196761 https://reactome.org/PathwayBrowser/#/R-BTA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Bos taurus 58937 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 58937 R-BTA-204169 https://reactome.org/PathwayBrowser/#/R-BTA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Bos taurus 58937 R-BTA-389611 https://reactome.org/PathwayBrowser/#/R-BTA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Bos taurus 58937 R-BTA-5693148 https://reactome.org/PathwayBrowser/#/R-BTA-5693148 BCKDK phosphorylates BCKDH IEA Bos taurus 58937 R-BTA-5693153 https://reactome.org/PathwayBrowser/#/R-BTA-5693153 PPM1K dephosphorylates p-BCKDH IEA Bos taurus 58937 R-BTA-5694018 https://reactome.org/PathwayBrowser/#/R-BTA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Bos taurus 58937 R-BTA-70713 https://reactome.org/PathwayBrowser/#/R-BTA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Bos taurus 58937 R-BTA-71037 https://reactome.org/PathwayBrowser/#/R-BTA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Bos taurus 58937 R-BTA-71324 https://reactome.org/PathwayBrowser/#/R-BTA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 58937 R-BTA-71335 https://reactome.org/PathwayBrowser/#/R-BTA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Bos taurus 58937 R-BTA-71401 https://reactome.org/PathwayBrowser/#/R-BTA-71401 OGDH dimer decarboxylates 2-OG IEA Bos taurus 58937 R-BTA-8875838 https://reactome.org/PathwayBrowser/#/R-BTA-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Bos taurus 58937 R-BTA-965067 https://reactome.org/PathwayBrowser/#/R-BTA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Bos taurus 58937 R-BTA-9853499 https://reactome.org/PathwayBrowser/#/R-BTA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 58937 R-BTA-9853512 https://reactome.org/PathwayBrowser/#/R-BTA-9853512 DLST transfers succinyl to CoA IEA Bos taurus 58937 R-BTA-9861616 https://reactome.org/PathwayBrowser/#/R-BTA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 58937 R-BTA-9861667 https://reactome.org/PathwayBrowser/#/R-BTA-9861667 DLAT trimer transfers acetyl to CoA IEA Bos taurus 58937 R-BTA-9861734 https://reactome.org/PathwayBrowser/#/R-BTA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Bos taurus 58937 R-CEL-163741 https://reactome.org/PathwayBrowser/#/R-CEL-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Caenorhabditis elegans 58937 R-CEL-163751 https://reactome.org/PathwayBrowser/#/R-CEL-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Caenorhabditis elegans 58937 R-CEL-196761 https://reactome.org/PathwayBrowser/#/R-CEL-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Caenorhabditis elegans 58937 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 58937 R-CEL-204169 https://reactome.org/PathwayBrowser/#/R-CEL-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Caenorhabditis elegans 58937 R-CEL-389611 https://reactome.org/PathwayBrowser/#/R-CEL-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Caenorhabditis elegans 58937 R-CEL-5694018 https://reactome.org/PathwayBrowser/#/R-CEL-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Caenorhabditis elegans 58937 R-CEL-70713 https://reactome.org/PathwayBrowser/#/R-CEL-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Caenorhabditis elegans 58937 R-CEL-71037 https://reactome.org/PathwayBrowser/#/R-CEL-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Caenorhabditis elegans 58937 R-CEL-71324 https://reactome.org/PathwayBrowser/#/R-CEL-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 58937 R-CEL-71335 https://reactome.org/PathwayBrowser/#/R-CEL-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Caenorhabditis elegans 58937 R-CEL-71401 https://reactome.org/PathwayBrowser/#/R-CEL-71401 OGDH dimer decarboxylates 2-OG IEA Caenorhabditis elegans 58937 R-CEL-8875838 https://reactome.org/PathwayBrowser/#/R-CEL-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Caenorhabditis elegans 58937 R-CEL-9853499 https://reactome.org/PathwayBrowser/#/R-CEL-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 58937 R-CEL-9853512 https://reactome.org/PathwayBrowser/#/R-CEL-9853512 DLST transfers succinyl to CoA IEA Caenorhabditis elegans 58937 R-CEL-9861616 https://reactome.org/PathwayBrowser/#/R-CEL-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 58937 R-CEL-9861667 https://reactome.org/PathwayBrowser/#/R-CEL-9861667 DLAT trimer transfers acetyl to CoA IEA Caenorhabditis elegans 58937 R-CEL-9861734 https://reactome.org/PathwayBrowser/#/R-CEL-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Caenorhabditis elegans 58937 R-CFA-163741 https://reactome.org/PathwayBrowser/#/R-CFA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Canis familiaris 58937 R-CFA-163751 https://reactome.org/PathwayBrowser/#/R-CFA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Canis familiaris 58937 R-CFA-196761 https://reactome.org/PathwayBrowser/#/R-CFA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Canis familiaris 58937 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 58937 R-CFA-204169 https://reactome.org/PathwayBrowser/#/R-CFA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Canis familiaris 58937 R-CFA-389611 https://reactome.org/PathwayBrowser/#/R-CFA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Canis familiaris 58937 R-CFA-5693148 https://reactome.org/PathwayBrowser/#/R-CFA-5693148 BCKDK phosphorylates BCKDH IEA Canis familiaris 58937 R-CFA-5693153 https://reactome.org/PathwayBrowser/#/R-CFA-5693153 PPM1K dephosphorylates p-BCKDH IEA Canis familiaris 58937 R-CFA-5694018 https://reactome.org/PathwayBrowser/#/R-CFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Canis familiaris 58937 R-CFA-70713 https://reactome.org/PathwayBrowser/#/R-CFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Canis familiaris 58937 R-CFA-71037 https://reactome.org/PathwayBrowser/#/R-CFA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Canis familiaris 58937 R-CFA-71324 https://reactome.org/PathwayBrowser/#/R-CFA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 58937 R-CFA-71335 https://reactome.org/PathwayBrowser/#/R-CFA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Canis familiaris 58937 R-CFA-71401 https://reactome.org/PathwayBrowser/#/R-CFA-71401 OGDH dimer decarboxylates 2-OG IEA Canis familiaris 58937 R-CFA-8875838 https://reactome.org/PathwayBrowser/#/R-CFA-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Canis familiaris 58937 R-CFA-965067 https://reactome.org/PathwayBrowser/#/R-CFA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Canis familiaris 58937 R-CFA-9853499 https://reactome.org/PathwayBrowser/#/R-CFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 58937 R-CFA-9853512 https://reactome.org/PathwayBrowser/#/R-CFA-9853512 DLST transfers succinyl to CoA IEA Canis familiaris 58937 R-CFA-9861616 https://reactome.org/PathwayBrowser/#/R-CFA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 58937 R-CFA-9861667 https://reactome.org/PathwayBrowser/#/R-CFA-9861667 DLAT trimer transfers acetyl to CoA IEA Canis familiaris 58937 R-CFA-9861734 https://reactome.org/PathwayBrowser/#/R-CFA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Canis familiaris 58937 R-DDI-196761 https://reactome.org/PathwayBrowser/#/R-DDI-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Dictyostelium discoideum 58937 R-DDI-389611 https://reactome.org/PathwayBrowser/#/R-DDI-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Dictyostelium discoideum 58937 R-DDI-5694018 https://reactome.org/PathwayBrowser/#/R-DDI-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Dictyostelium discoideum 58937 R-DDI-70713 https://reactome.org/PathwayBrowser/#/R-DDI-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Dictyostelium discoideum 58937 R-DDI-71037 https://reactome.org/PathwayBrowser/#/R-DDI-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Dictyostelium discoideum 58937 R-DDI-71401 https://reactome.org/PathwayBrowser/#/R-DDI-71401 OGDH dimer decarboxylates 2-OG IEA Dictyostelium discoideum 58937 R-DDI-8875838 https://reactome.org/PathwayBrowser/#/R-DDI-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Dictyostelium discoideum 58937 R-DDI-9853499 https://reactome.org/PathwayBrowser/#/R-DDI-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 58937 R-DDI-9853512 https://reactome.org/PathwayBrowser/#/R-DDI-9853512 DLST transfers succinyl to CoA IEA Dictyostelium discoideum 58937 R-DDI-9861616 https://reactome.org/PathwayBrowser/#/R-DDI-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 58937 R-DDI-9861667 https://reactome.org/PathwayBrowser/#/R-DDI-9861667 DLAT trimer transfers acetyl to CoA IEA Dictyostelium discoideum 58937 R-DDI-9861734 https://reactome.org/PathwayBrowser/#/R-DDI-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Dictyostelium discoideum 58937 R-DME-163741 https://reactome.org/PathwayBrowser/#/R-DME-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Drosophila melanogaster 58937 R-DME-163751 https://reactome.org/PathwayBrowser/#/R-DME-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Drosophila melanogaster 58937 R-DME-196761 https://reactome.org/PathwayBrowser/#/R-DME-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Drosophila melanogaster 58937 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 58937 R-DME-204169 https://reactome.org/PathwayBrowser/#/R-DME-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Drosophila melanogaster 58937 R-DME-389611 https://reactome.org/PathwayBrowser/#/R-DME-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Drosophila melanogaster 58937 R-DME-5694018 https://reactome.org/PathwayBrowser/#/R-DME-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Drosophila melanogaster 58937 R-DME-70713 https://reactome.org/PathwayBrowser/#/R-DME-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Drosophila melanogaster 58937 R-DME-71037 https://reactome.org/PathwayBrowser/#/R-DME-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Drosophila melanogaster 58937 R-DME-71324 https://reactome.org/PathwayBrowser/#/R-DME-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 58937 R-DME-71335 https://reactome.org/PathwayBrowser/#/R-DME-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Drosophila melanogaster 58937 R-DME-71401 https://reactome.org/PathwayBrowser/#/R-DME-71401 OGDH dimer decarboxylates 2-OG IEA Drosophila melanogaster 58937 R-DME-8875838 https://reactome.org/PathwayBrowser/#/R-DME-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Drosophila melanogaster 58937 R-DME-9853499 https://reactome.org/PathwayBrowser/#/R-DME-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 58937 R-DME-9853512 https://reactome.org/PathwayBrowser/#/R-DME-9853512 DLST transfers succinyl to CoA IEA Drosophila melanogaster 58937 R-DME-9861616 https://reactome.org/PathwayBrowser/#/R-DME-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 58937 R-DME-9861667 https://reactome.org/PathwayBrowser/#/R-DME-9861667 DLAT trimer transfers acetyl to CoA IEA Drosophila melanogaster 58937 R-DME-9861734 https://reactome.org/PathwayBrowser/#/R-DME-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Drosophila melanogaster 58937 R-DRE-196761 https://reactome.org/PathwayBrowser/#/R-DRE-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Danio rerio 58937 R-DRE-389611 https://reactome.org/PathwayBrowser/#/R-DRE-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Danio rerio 58937 R-DRE-5694018 https://reactome.org/PathwayBrowser/#/R-DRE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Danio rerio 58937 R-DRE-70713 https://reactome.org/PathwayBrowser/#/R-DRE-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Danio rerio 58937 R-DRE-71037 https://reactome.org/PathwayBrowser/#/R-DRE-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Danio rerio 58937 R-DRE-71401 https://reactome.org/PathwayBrowser/#/R-DRE-71401 OGDH dimer decarboxylates 2-OG IEA Danio rerio 58937 R-DRE-8875838 https://reactome.org/PathwayBrowser/#/R-DRE-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Danio rerio 58937 R-DRE-9853499 https://reactome.org/PathwayBrowser/#/R-DRE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Danio rerio 58937 R-DRE-9853512 https://reactome.org/PathwayBrowser/#/R-DRE-9853512 DLST transfers succinyl to CoA IEA Danio rerio 58937 R-GGA-163741 https://reactome.org/PathwayBrowser/#/R-GGA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Gallus gallus 58937 R-GGA-163751 https://reactome.org/PathwayBrowser/#/R-GGA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Gallus gallus 58937 R-GGA-196761 https://reactome.org/PathwayBrowser/#/R-GGA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Gallus gallus 58937 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 58937 R-GGA-204169 https://reactome.org/PathwayBrowser/#/R-GGA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Gallus gallus 58937 R-GGA-389611 https://reactome.org/PathwayBrowser/#/R-GGA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Gallus gallus 58937 R-GGA-5693153 https://reactome.org/PathwayBrowser/#/R-GGA-5693153 PPM1K dephosphorylates p-BCKDH IEA Gallus gallus 58937 R-GGA-5694018 https://reactome.org/PathwayBrowser/#/R-GGA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Gallus gallus 58937 R-GGA-70713 https://reactome.org/PathwayBrowser/#/R-GGA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Gallus gallus 58937 R-GGA-71037 https://reactome.org/PathwayBrowser/#/R-GGA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Gallus gallus 58937 R-GGA-71324 https://reactome.org/PathwayBrowser/#/R-GGA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 58937 R-GGA-71335 https://reactome.org/PathwayBrowser/#/R-GGA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Gallus gallus 58937 R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus 58937 R-GGA-8875838 https://reactome.org/PathwayBrowser/#/R-GGA-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Gallus gallus 58937 R-GGA-9853499 https://reactome.org/PathwayBrowser/#/R-GGA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 58937 R-GGA-9853512 https://reactome.org/PathwayBrowser/#/R-GGA-9853512 DLST transfers succinyl to CoA IEA Gallus gallus 58937 R-GGA-9861616 https://reactome.org/PathwayBrowser/#/R-GGA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 58937 R-GGA-9861667 https://reactome.org/PathwayBrowser/#/R-GGA-9861667 DLAT trimer transfers acetyl to CoA IEA Gallus gallus 58937 R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus 58937 R-HSA-163741 https://reactome.org/PathwayBrowser/#/R-HSA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate TAS Homo sapiens 58937 R-HSA-163751 https://reactome.org/PathwayBrowser/#/R-HSA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate TAS Homo sapiens 58937 R-HSA-196761 https://reactome.org/PathwayBrowser/#/R-HSA-196761 2xTPK1:Mg2+ phosphorylates THMN TAS Homo sapiens 58937 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 58937 R-HSA-204169 https://reactome.org/PathwayBrowser/#/R-HSA-204169 PDP1,2 dephosphorylate p-lipo-PDH TAS Homo sapiens 58937 R-HSA-389611 https://reactome.org/PathwayBrowser/#/R-HSA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA TAS Homo sapiens 58937 R-HSA-5693148 https://reactome.org/PathwayBrowser/#/R-HSA-5693148 BCKDK phosphorylates BCKDH TAS Homo sapiens 58937 R-HSA-5693153 https://reactome.org/PathwayBrowser/#/R-HSA-5693153 PPM1K dephosphorylates p-BCKDH TAS Homo sapiens 58937 R-HSA-5694018 https://reactome.org/PathwayBrowser/#/R-HSA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate TAS Homo sapiens 58937 R-HSA-70713 https://reactome.org/PathwayBrowser/#/R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV TAS Homo sapiens 58937 R-HSA-71037 https://reactome.org/PathwayBrowser/#/R-HSA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ TAS Homo sapiens 58937 R-HSA-71324 https://reactome.org/PathwayBrowser/#/R-HSA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 58937 R-HSA-71335 https://reactome.org/PathwayBrowser/#/R-HSA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate TAS Homo sapiens 58937 R-HSA-71401 https://reactome.org/PathwayBrowser/#/R-HSA-71401 OGDH dimer decarboxylates 2-OG TAS Homo sapiens 58937 R-HSA-8875838 https://reactome.org/PathwayBrowser/#/R-HSA-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix TAS Homo sapiens 58937 R-HSA-965067 https://reactome.org/PathwayBrowser/#/R-HSA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP TAS Homo sapiens 58937 R-HSA-9761852 https://reactome.org/PathwayBrowser/#/R-HSA-9761852 NFE2L2-dependent TKT gene expression TAS Homo sapiens 58937 R-HSA-9853499 https://reactome.org/PathwayBrowser/#/R-HSA-9853499 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 58937 R-HSA-9853512 https://reactome.org/PathwayBrowser/#/R-HSA-9853512 DLST transfers succinyl to CoA TAS Homo sapiens 58937 R-HSA-9861616 https://reactome.org/PathwayBrowser/#/R-HSA-9861616 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 58937 R-HSA-9861667 https://reactome.org/PathwayBrowser/#/R-HSA-9861667 DLAT trimer transfers acetyl to CoA TAS Homo sapiens 58937 R-HSA-9861734 https://reactome.org/PathwayBrowser/#/R-HSA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT TAS Homo sapiens 58937 R-HSA-997381 https://reactome.org/PathwayBrowser/#/R-HSA-997381 TDPK phosphorylates ThDP to ThTP TAS Homo sapiens 58937 R-MMU-163741 https://reactome.org/PathwayBrowser/#/R-MMU-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Mus musculus 58937 R-MMU-163751 https://reactome.org/PathwayBrowser/#/R-MMU-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Mus musculus 58937 R-MMU-196761 https://reactome.org/PathwayBrowser/#/R-MMU-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Mus musculus 58937 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 58937 R-MMU-204169 https://reactome.org/PathwayBrowser/#/R-MMU-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Mus musculus 58937 R-MMU-389611 https://reactome.org/PathwayBrowser/#/R-MMU-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Mus musculus 58937 R-MMU-5693148 https://reactome.org/PathwayBrowser/#/R-MMU-5693148 BCKDK phosphorylates BCKDH IEA Mus musculus 58937 R-MMU-5693153 https://reactome.org/PathwayBrowser/#/R-MMU-5693153 PPM1K dephosphorylates p-BCKDH IEA Mus musculus 58937 R-MMU-5694018 https://reactome.org/PathwayBrowser/#/R-MMU-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Mus musculus 58937 R-MMU-70713 https://reactome.org/PathwayBrowser/#/R-MMU-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Mus musculus 58937 R-MMU-71037 https://reactome.org/PathwayBrowser/#/R-MMU-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Mus musculus 58937 R-MMU-71324 https://reactome.org/PathwayBrowser/#/R-MMU-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 58937 R-MMU-71335 https://reactome.org/PathwayBrowser/#/R-MMU-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Mus musculus 58937 R-MMU-71401 https://reactome.org/PathwayBrowser/#/R-MMU-71401 OGDH dimer decarboxylates 2-OG IEA Mus musculus 58937 R-MMU-8875838 https://reactome.org/PathwayBrowser/#/R-MMU-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Mus musculus 58937 R-MMU-965067 https://reactome.org/PathwayBrowser/#/R-MMU-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Mus musculus 58937 R-MMU-9853499 https://reactome.org/PathwayBrowser/#/R-MMU-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 58937 R-MMU-9853512 https://reactome.org/PathwayBrowser/#/R-MMU-9853512 DLST transfers succinyl to CoA IEA Mus musculus 58937 R-MMU-9861616 https://reactome.org/PathwayBrowser/#/R-MMU-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 58937 R-MMU-9861667 https://reactome.org/PathwayBrowser/#/R-MMU-9861667 DLAT trimer transfers acetyl to CoA IEA Mus musculus 58937 R-MMU-9861734 https://reactome.org/PathwayBrowser/#/R-MMU-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Mus musculus 58937 R-PFA-196761 https://reactome.org/PathwayBrowser/#/R-PFA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Plasmodium falciparum 58937 R-PFA-5694018 https://reactome.org/PathwayBrowser/#/R-PFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Plasmodium falciparum 58937 R-PFA-70713 https://reactome.org/PathwayBrowser/#/R-PFA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Plasmodium falciparum 58937 R-PFA-71401 https://reactome.org/PathwayBrowser/#/R-PFA-71401 OGDH dimer decarboxylates 2-OG IEA Plasmodium falciparum 58937 R-PFA-9853499 https://reactome.org/PathwayBrowser/#/R-PFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Plasmodium falciparum 58937 R-PFA-9853512 https://reactome.org/PathwayBrowser/#/R-PFA-9853512 DLST transfers succinyl to CoA IEA Plasmodium falciparum 58937 R-RNO-163741 https://reactome.org/PathwayBrowser/#/R-RNO-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Rattus norvegicus 58937 R-RNO-163751 https://reactome.org/PathwayBrowser/#/R-RNO-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Rattus norvegicus 58937 R-RNO-196761 https://reactome.org/PathwayBrowser/#/R-RNO-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Rattus norvegicus 58937 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 58937 R-RNO-204169 https://reactome.org/PathwayBrowser/#/R-RNO-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Rattus norvegicus 58937 R-RNO-389611 https://reactome.org/PathwayBrowser/#/R-RNO-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Rattus norvegicus 58937 R-RNO-5693148 https://reactome.org/PathwayBrowser/#/R-RNO-5693148 BCKDK phosphorylates BCKDH IEA Rattus norvegicus 58937 R-RNO-5693153 https://reactome.org/PathwayBrowser/#/R-RNO-5693153 PPM1K dephosphorylates p-BCKDH IEA Rattus norvegicus 58937 R-RNO-5694018 https://reactome.org/PathwayBrowser/#/R-RNO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Rattus norvegicus 58937 R-RNO-70713 https://reactome.org/PathwayBrowser/#/R-RNO-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Rattus norvegicus 58937 R-RNO-71037 https://reactome.org/PathwayBrowser/#/R-RNO-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Rattus norvegicus 58937 R-RNO-71324 https://reactome.org/PathwayBrowser/#/R-RNO-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 58937 R-RNO-71335 https://reactome.org/PathwayBrowser/#/R-RNO-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Rattus norvegicus 58937 R-RNO-71401 https://reactome.org/PathwayBrowser/#/R-RNO-71401 OGDH dimer decarboxylates 2-OG IEA Rattus norvegicus 58937 R-RNO-965067 https://reactome.org/PathwayBrowser/#/R-RNO-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Rattus norvegicus 58937 R-RNO-9853499 https://reactome.org/PathwayBrowser/#/R-RNO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 58937 R-RNO-9853512 https://reactome.org/PathwayBrowser/#/R-RNO-9853512 DLST transfers succinyl to CoA IEA Rattus norvegicus 58937 R-RNO-9861616 https://reactome.org/PathwayBrowser/#/R-RNO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 58937 R-RNO-9861667 https://reactome.org/PathwayBrowser/#/R-RNO-9861667 DLAT trimer transfers acetyl to CoA IEA Rattus norvegicus 58937 R-RNO-9861734 https://reactome.org/PathwayBrowser/#/R-RNO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Rattus norvegicus 58937 R-SCE-196761 https://reactome.org/PathwayBrowser/#/R-SCE-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Saccharomyces cerevisiae 58937 R-SCE-389611 https://reactome.org/PathwayBrowser/#/R-SCE-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Saccharomyces cerevisiae 58937 R-SCE-5694018 https://reactome.org/PathwayBrowser/#/R-SCE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Saccharomyces cerevisiae 58937 R-SCE-71401 https://reactome.org/PathwayBrowser/#/R-SCE-71401 OGDH dimer decarboxylates 2-OG IEA Saccharomyces cerevisiae 58937 R-SCE-8875838 https://reactome.org/PathwayBrowser/#/R-SCE-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Saccharomyces cerevisiae 58937 R-SCE-9853499 https://reactome.org/PathwayBrowser/#/R-SCE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 58937 R-SCE-9853512 https://reactome.org/PathwayBrowser/#/R-SCE-9853512 DLST transfers succinyl to CoA IEA Saccharomyces cerevisiae 58937 R-SCE-9861616 https://reactome.org/PathwayBrowser/#/R-SCE-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 58937 R-SCE-9861667 https://reactome.org/PathwayBrowser/#/R-SCE-9861667 DLAT trimer transfers acetyl to CoA IEA Saccharomyces cerevisiae 58937 R-SCE-9861734 https://reactome.org/PathwayBrowser/#/R-SCE-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Saccharomyces cerevisiae 58937 R-SPO-196761 https://reactome.org/PathwayBrowser/#/R-SPO-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Schizosaccharomyces pombe 58937 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 58937 R-SPO-389611 https://reactome.org/PathwayBrowser/#/R-SPO-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Schizosaccharomyces pombe 58937 R-SPO-5694018 https://reactome.org/PathwayBrowser/#/R-SPO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Schizosaccharomyces pombe 58937 R-SPO-71401 https://reactome.org/PathwayBrowser/#/R-SPO-71401 OGDH dimer decarboxylates 2-OG IEA Schizosaccharomyces pombe 58937 R-SPO-8875838 https://reactome.org/PathwayBrowser/#/R-SPO-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Schizosaccharomyces pombe 58937 R-SPO-9853499 https://reactome.org/PathwayBrowser/#/R-SPO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 58937 R-SPO-9853512 https://reactome.org/PathwayBrowser/#/R-SPO-9853512 DLST transfers succinyl to CoA IEA Schizosaccharomyces pombe 58937 R-SPO-9861616 https://reactome.org/PathwayBrowser/#/R-SPO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 58937 R-SPO-9861667 https://reactome.org/PathwayBrowser/#/R-SPO-9861667 DLAT trimer transfers acetyl to CoA IEA Schizosaccharomyces pombe 58937 R-SPO-9861734 https://reactome.org/PathwayBrowser/#/R-SPO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Schizosaccharomyces pombe 58937 R-SSC-163741 https://reactome.org/PathwayBrowser/#/R-SSC-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Sus scrofa 58937 R-SSC-163751 https://reactome.org/PathwayBrowser/#/R-SSC-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Sus scrofa 58937 R-SSC-196761 https://reactome.org/PathwayBrowser/#/R-SSC-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Sus scrofa 58937 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 58937 R-SSC-204169 https://reactome.org/PathwayBrowser/#/R-SSC-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Sus scrofa 58937 R-SSC-389611 https://reactome.org/PathwayBrowser/#/R-SSC-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Sus scrofa 58937 R-SSC-5693148 https://reactome.org/PathwayBrowser/#/R-SSC-5693148 BCKDK phosphorylates BCKDH IEA Sus scrofa 58937 R-SSC-5693153 https://reactome.org/PathwayBrowser/#/R-SSC-5693153 PPM1K dephosphorylates p-BCKDH IEA Sus scrofa 58937 R-SSC-5694018 https://reactome.org/PathwayBrowser/#/R-SSC-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Sus scrofa 58937 R-SSC-70713 https://reactome.org/PathwayBrowser/#/R-SSC-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Sus scrofa 58937 R-SSC-71037 https://reactome.org/PathwayBrowser/#/R-SSC-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Sus scrofa 58937 R-SSC-71324 https://reactome.org/PathwayBrowser/#/R-SSC-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 58937 R-SSC-71335 https://reactome.org/PathwayBrowser/#/R-SSC-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Sus scrofa 58937 R-SSC-71401 https://reactome.org/PathwayBrowser/#/R-SSC-71401 OGDH dimer decarboxylates 2-OG IEA Sus scrofa 58937 R-SSC-8875838 https://reactome.org/PathwayBrowser/#/R-SSC-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Sus scrofa 58937 R-SSC-965067 https://reactome.org/PathwayBrowser/#/R-SSC-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Sus scrofa 58937 R-SSC-9853499 https://reactome.org/PathwayBrowser/#/R-SSC-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 58937 R-SSC-9853512 https://reactome.org/PathwayBrowser/#/R-SSC-9853512 DLST transfers succinyl to CoA IEA Sus scrofa 58937 R-SSC-9861616 https://reactome.org/PathwayBrowser/#/R-SSC-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 58937 R-SSC-9861667 https://reactome.org/PathwayBrowser/#/R-SSC-9861667 DLAT trimer transfers acetyl to CoA IEA Sus scrofa 58937 R-SSC-9861734 https://reactome.org/PathwayBrowser/#/R-SSC-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Sus scrofa 58937 R-XTR-163741 https://reactome.org/PathwayBrowser/#/R-XTR-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Xenopus tropicalis 58937 R-XTR-163751 https://reactome.org/PathwayBrowser/#/R-XTR-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Xenopus tropicalis 58937 R-XTR-196761 https://reactome.org/PathwayBrowser/#/R-XTR-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Xenopus tropicalis 58937 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 58937 R-XTR-389611 https://reactome.org/PathwayBrowser/#/R-XTR-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Xenopus tropicalis 58937 R-XTR-5693148 https://reactome.org/PathwayBrowser/#/R-XTR-5693148 BCKDK phosphorylates BCKDH IEA Xenopus tropicalis 58937 R-XTR-5694018 https://reactome.org/PathwayBrowser/#/R-XTR-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Xenopus tropicalis 58937 R-XTR-70713 https://reactome.org/PathwayBrowser/#/R-XTR-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV IEA Xenopus tropicalis 58937 R-XTR-71037 https://reactome.org/PathwayBrowser/#/R-XTR-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ IEA Xenopus tropicalis 58937 R-XTR-71324 https://reactome.org/PathwayBrowser/#/R-XTR-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 58937 R-XTR-71335 https://reactome.org/PathwayBrowser/#/R-XTR-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Xenopus tropicalis 58937 R-XTR-71401 https://reactome.org/PathwayBrowser/#/R-XTR-71401 OGDH dimer decarboxylates 2-OG IEA Xenopus tropicalis 58937 R-XTR-8875838 https://reactome.org/PathwayBrowser/#/R-XTR-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix IEA Xenopus tropicalis 58937 R-XTR-965067 https://reactome.org/PathwayBrowser/#/R-XTR-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Xenopus tropicalis 58937 R-XTR-9853499 https://reactome.org/PathwayBrowser/#/R-XTR-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 58937 R-XTR-9853512 https://reactome.org/PathwayBrowser/#/R-XTR-9853512 DLST transfers succinyl to CoA IEA Xenopus tropicalis 58937 R-XTR-9861616 https://reactome.org/PathwayBrowser/#/R-XTR-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 58937 R-XTR-9861667 https://reactome.org/PathwayBrowser/#/R-XTR-9861667 DLAT trimer transfers acetyl to CoA IEA Xenopus tropicalis 58937 R-XTR-9861734 https://reactome.org/PathwayBrowser/#/R-XTR-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Xenopus tropicalis 58961 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 58961 R-BTA-517536 https://reactome.org/PathwayBrowser/#/R-BTA-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Bos taurus 58961 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 58961 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 58961 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 58961 R-CFA-517536 https://reactome.org/PathwayBrowser/#/R-CFA-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Canis familiaris 58961 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 58961 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 58961 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 58961 R-GGA-517536 https://reactome.org/PathwayBrowser/#/R-GGA-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Gallus gallus 58961 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 58961 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 58961 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 58961 R-HSA-517536 https://reactome.org/PathwayBrowser/#/R-HSA-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine TAS Homo sapiens 58961 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 58961 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 58961 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 58961 R-MMU-517536 https://reactome.org/PathwayBrowser/#/R-MMU-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Mus musculus 58961 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 58961 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 58961 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 58961 R-RNO-517536 https://reactome.org/PathwayBrowser/#/R-RNO-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Rattus norvegicus 58961 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 58961 R-SSC-517536 https://reactome.org/PathwayBrowser/#/R-SSC-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Sus scrofa 58961 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 58961 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 58961 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 58961 R-XTR-517536 https://reactome.org/PathwayBrowser/#/R-XTR-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Xenopus tropicalis 58961 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 58961 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 59039 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 59039 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 59039 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 59039 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 59039 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 59039 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 59039 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 59039 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 59039 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 59039 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 59080 R-BTA-8951499 https://reactome.org/PathwayBrowser/#/R-BTA-8951499 Loading of antigenic peptides on to class I MHC IEA Bos taurus 59080 R-BTA-901047 https://reactome.org/PathwayBrowser/#/R-BTA-901047 Binding of ERp57 IEA Bos taurus 59080 R-BTA-983138 https://reactome.org/PathwayBrowser/#/R-BTA-983138 Transport of MHC heterotrimer to ER exit site IEA Bos taurus 59080 R-BTA-983142 https://reactome.org/PathwayBrowser/#/R-BTA-983142 Formation of peptide loading complex (PLC) IEA Bos taurus 59080 R-BTA-983145 https://reactome.org/PathwayBrowser/#/R-BTA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Bos taurus 59080 R-BTA-983146 https://reactome.org/PathwayBrowser/#/R-BTA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Bos taurus 59080 R-BTA-983161 https://reactome.org/PathwayBrowser/#/R-BTA-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Bos taurus 59080 R-BTA-983421 https://reactome.org/PathwayBrowser/#/R-BTA-983421 Journey of cargo through Golgi complex IEA Bos taurus 59080 R-BTA-983422 https://reactome.org/PathwayBrowser/#/R-BTA-983422 Disassembly of COPII coated vesicle IEA Bos taurus 59080 R-BTA-983424 https://reactome.org/PathwayBrowser/#/R-BTA-983424 Budding of COPII coated vesicle IEA Bos taurus 59080 R-BTA-983425 https://reactome.org/PathwayBrowser/#/R-BTA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Bos taurus 59080 R-BTA-983427 https://reactome.org/PathwayBrowser/#/R-BTA-983427 Expression of peptide bound class I MHC on cell surface IEA Bos taurus 59080 R-CEL-901047 https://reactome.org/PathwayBrowser/#/R-CEL-901047 Binding of ERp57 IEA Caenorhabditis elegans 59080 R-CFA-8951499 https://reactome.org/PathwayBrowser/#/R-CFA-8951499 Loading of antigenic peptides on to class I MHC IEA Canis familiaris 59080 R-CFA-901047 https://reactome.org/PathwayBrowser/#/R-CFA-901047 Binding of ERp57 IEA Canis familiaris 59080 R-CFA-983138 https://reactome.org/PathwayBrowser/#/R-CFA-983138 Transport of MHC heterotrimer to ER exit site IEA Canis familiaris 59080 R-CFA-983145 https://reactome.org/PathwayBrowser/#/R-CFA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Canis familiaris 59080 R-CFA-983146 https://reactome.org/PathwayBrowser/#/R-CFA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Canis familiaris 59080 R-CFA-983421 https://reactome.org/PathwayBrowser/#/R-CFA-983421 Journey of cargo through Golgi complex IEA Canis familiaris 59080 R-CFA-983422 https://reactome.org/PathwayBrowser/#/R-CFA-983422 Disassembly of COPII coated vesicle IEA Canis familiaris 59080 R-CFA-983424 https://reactome.org/PathwayBrowser/#/R-CFA-983424 Budding of COPII coated vesicle IEA Canis familiaris 59080 R-CFA-983425 https://reactome.org/PathwayBrowser/#/R-CFA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Canis familiaris 59080 R-CFA-983427 https://reactome.org/PathwayBrowser/#/R-CFA-983427 Expression of peptide bound class I MHC on cell surface IEA Canis familiaris 59080 R-DDI-901047 https://reactome.org/PathwayBrowser/#/R-DDI-901047 Binding of ERp57 IEA Dictyostelium discoideum 59080 R-DME-901047 https://reactome.org/PathwayBrowser/#/R-DME-901047 Binding of ERp57 IEA Drosophila melanogaster 59080 R-DRE-8951499 https://reactome.org/PathwayBrowser/#/R-DRE-8951499 Loading of antigenic peptides on to class I MHC IEA Danio rerio 59080 R-DRE-901047 https://reactome.org/PathwayBrowser/#/R-DRE-901047 Binding of ERp57 IEA Danio rerio 59080 R-DRE-983138 https://reactome.org/PathwayBrowser/#/R-DRE-983138 Transport of MHC heterotrimer to ER exit site IEA Danio rerio 59080 R-DRE-983145 https://reactome.org/PathwayBrowser/#/R-DRE-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Danio rerio 59080 R-DRE-983146 https://reactome.org/PathwayBrowser/#/R-DRE-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Danio rerio 59080 R-DRE-983421 https://reactome.org/PathwayBrowser/#/R-DRE-983421 Journey of cargo through Golgi complex IEA Danio rerio 59080 R-DRE-983424 https://reactome.org/PathwayBrowser/#/R-DRE-983424 Budding of COPII coated vesicle IEA Danio rerio 59080 R-DRE-983425 https://reactome.org/PathwayBrowser/#/R-DRE-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Danio rerio 59080 R-DRE-983427 https://reactome.org/PathwayBrowser/#/R-DRE-983427 Expression of peptide bound class I MHC on cell surface IEA Danio rerio 59080 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus 59080 R-GGA-901047 https://reactome.org/PathwayBrowser/#/R-GGA-901047 Binding of ERp57 IEA Gallus gallus 59080 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus 59080 R-GGA-983145 https://reactome.org/PathwayBrowser/#/R-GGA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Gallus gallus 59080 R-GGA-983146 https://reactome.org/PathwayBrowser/#/R-GGA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Gallus gallus 59080 R-GGA-983421 https://reactome.org/PathwayBrowser/#/R-GGA-983421 Journey of cargo through Golgi complex IEA Gallus gallus 59080 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus 59080 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus 59080 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus 59080 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus 59080 R-HSA-1017228 https://reactome.org/PathwayBrowser/#/R-HSA-1017228 Glycoproteins with lesser folding defects get transported back to the ER and the CNX/CRT complex TAS Homo sapiens 59080 R-HSA-532667 https://reactome.org/PathwayBrowser/#/R-HSA-532667 Removal of the second glucose by glucosidase II TAS Homo sapiens 59080 R-HSA-535717 https://reactome.org/PathwayBrowser/#/R-HSA-535717 Binding of calnexin/calreticulin to the unfolded protein TAS Homo sapiens 59080 R-HSA-548890 https://reactome.org/PathwayBrowser/#/R-HSA-548890 Removal of the third glucose by glucosidase II and release from the chaperone TAS Homo sapiens 59080 R-HSA-8951499 https://reactome.org/PathwayBrowser/#/R-HSA-8951499 Loading of antigenic peptides on to class I MHC TAS Homo sapiens 59080 R-HSA-901047 https://reactome.org/PathwayBrowser/#/R-HSA-901047 Binding of ERp57 TAS Homo sapiens 59080 R-HSA-9755328 https://reactome.org/PathwayBrowser/#/R-HSA-9755328 SARS-CoV-2 8 binds class I MHC TAS Homo sapiens 59080 R-HSA-9755359 https://reactome.org/PathwayBrowser/#/R-HSA-9755359 SARS-CoV-2 8:class I MHC binds BECN1 TAS Homo sapiens 59080 R-HSA-983138 https://reactome.org/PathwayBrowser/#/R-HSA-983138 Transport of MHC heterotrimer to ER exit site TAS Homo sapiens 59080 R-HSA-983142 https://reactome.org/PathwayBrowser/#/R-HSA-983142 Formation of peptide loading complex (PLC) TAS Homo sapiens 59080 R-HSA-983145 https://reactome.org/PathwayBrowser/#/R-HSA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin TAS Homo sapiens 59080 R-HSA-983146 https://reactome.org/PathwayBrowser/#/R-HSA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC TAS Homo sapiens 59080 R-HSA-983148 https://reactome.org/PathwayBrowser/#/R-HSA-983148 Interaction of Erp57 with MHC class I HC IEA Homo sapiens 59080 R-HSA-983161 https://reactome.org/PathwayBrowser/#/R-HSA-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex TAS Homo sapiens 59080 R-HSA-983421 https://reactome.org/PathwayBrowser/#/R-HSA-983421 Journey of cargo through Golgi complex TAS Homo sapiens 59080 R-HSA-983422 https://reactome.org/PathwayBrowser/#/R-HSA-983422 Disassembly of COPII coated vesicle TAS Homo sapiens 59080 R-HSA-983424 https://reactome.org/PathwayBrowser/#/R-HSA-983424 Budding of COPII coated vesicle TAS Homo sapiens 59080 R-HSA-983425 https://reactome.org/PathwayBrowser/#/R-HSA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle TAS Homo sapiens 59080 R-HSA-983426 https://reactome.org/PathwayBrowser/#/R-HSA-983426 Capturing cargo and formation of prebudding complex TAS Homo sapiens 59080 R-HSA-983427 https://reactome.org/PathwayBrowser/#/R-HSA-983427 Expression of peptide bound class I MHC on cell surface TAS Homo sapiens 59080 R-MMU-8951499 https://reactome.org/PathwayBrowser/#/R-MMU-8951499 Loading of antigenic peptides on to class I MHC IEA Mus musculus 59080 R-MMU-901047 https://reactome.org/PathwayBrowser/#/R-MMU-901047 Binding of ERp57 IEA Mus musculus 59080 R-MMU-983138 https://reactome.org/PathwayBrowser/#/R-MMU-983138 Transport of MHC heterotrimer to ER exit site IEA Mus musculus 59080 R-MMU-983142 https://reactome.org/PathwayBrowser/#/R-MMU-983142 Formation of peptide loading complex (PLC) IEA Mus musculus 59080 R-MMU-983145 https://reactome.org/PathwayBrowser/#/R-MMU-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Mus musculus 59080 R-MMU-983146 https://reactome.org/PathwayBrowser/#/R-MMU-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Mus musculus 59080 R-MMU-983161 https://reactome.org/PathwayBrowser/#/R-MMU-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Mus musculus 59080 R-MMU-983421 https://reactome.org/PathwayBrowser/#/R-MMU-983421 Journey of cargo through Golgi complex IEA Mus musculus 59080 R-MMU-983422 https://reactome.org/PathwayBrowser/#/R-MMU-983422 Disassembly of COPII coated vesicle IEA Mus musculus 59080 R-MMU-983424 https://reactome.org/PathwayBrowser/#/R-MMU-983424 Budding of COPII coated vesicle IEA Mus musculus 59080 R-MMU-983425 https://reactome.org/PathwayBrowser/#/R-MMU-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Mus musculus 59080 R-MMU-983427 https://reactome.org/PathwayBrowser/#/R-MMU-983427 Expression of peptide bound class I MHC on cell surface IEA Mus musculus 59080 R-RNO-8951499 https://reactome.org/PathwayBrowser/#/R-RNO-8951499 Loading of antigenic peptides on to class I MHC IEA Rattus norvegicus 59080 R-RNO-901047 https://reactome.org/PathwayBrowser/#/R-RNO-901047 Binding of ERp57 IEA Rattus norvegicus 59080 R-RNO-983138 https://reactome.org/PathwayBrowser/#/R-RNO-983138 Transport of MHC heterotrimer to ER exit site IEA Rattus norvegicus 59080 R-RNO-983142 https://reactome.org/PathwayBrowser/#/R-RNO-983142 Formation of peptide loading complex (PLC) IEA Rattus norvegicus 59080 R-RNO-983145 https://reactome.org/PathwayBrowser/#/R-RNO-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Rattus norvegicus 59080 R-RNO-983146 https://reactome.org/PathwayBrowser/#/R-RNO-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Rattus norvegicus 59080 R-RNO-983161 https://reactome.org/PathwayBrowser/#/R-RNO-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Rattus norvegicus 59080 R-RNO-983421 https://reactome.org/PathwayBrowser/#/R-RNO-983421 Journey of cargo through Golgi complex IEA Rattus norvegicus 59080 R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus 59080 R-RNO-983424 https://reactome.org/PathwayBrowser/#/R-RNO-983424 Budding of COPII coated vesicle IEA Rattus norvegicus 59080 R-RNO-983425 https://reactome.org/PathwayBrowser/#/R-RNO-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Rattus norvegicus 59080 R-RNO-983427 https://reactome.org/PathwayBrowser/#/R-RNO-983427 Expression of peptide bound class I MHC on cell surface IEA Rattus norvegicus 59080 R-SCE-901047 https://reactome.org/PathwayBrowser/#/R-SCE-901047 Binding of ERp57 IEA Saccharomyces cerevisiae 59080 R-SPO-901047 https://reactome.org/PathwayBrowser/#/R-SPO-901047 Binding of ERp57 IEA Schizosaccharomyces pombe 59080 R-SSC-8951499 https://reactome.org/PathwayBrowser/#/R-SSC-8951499 Loading of antigenic peptides on to class I MHC IEA Sus scrofa 59080 R-SSC-901047 https://reactome.org/PathwayBrowser/#/R-SSC-901047 Binding of ERp57 IEA Sus scrofa 59080 R-SSC-983138 https://reactome.org/PathwayBrowser/#/R-SSC-983138 Transport of MHC heterotrimer to ER exit site IEA Sus scrofa 59080 R-SSC-983142 https://reactome.org/PathwayBrowser/#/R-SSC-983142 Formation of peptide loading complex (PLC) IEA Sus scrofa 59080 R-SSC-983145 https://reactome.org/PathwayBrowser/#/R-SSC-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Sus scrofa 59080 R-SSC-983146 https://reactome.org/PathwayBrowser/#/R-SSC-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Sus scrofa 59080 R-SSC-983161 https://reactome.org/PathwayBrowser/#/R-SSC-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Sus scrofa 59080 R-SSC-983421 https://reactome.org/PathwayBrowser/#/R-SSC-983421 Journey of cargo through Golgi complex IEA Sus scrofa 59080 R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa 59080 R-SSC-983424 https://reactome.org/PathwayBrowser/#/R-SSC-983424 Budding of COPII coated vesicle IEA Sus scrofa 59080 R-SSC-983425 https://reactome.org/PathwayBrowser/#/R-SSC-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Sus scrofa 59080 R-SSC-983427 https://reactome.org/PathwayBrowser/#/R-SSC-983427 Expression of peptide bound class I MHC on cell surface IEA Sus scrofa 59080 R-XTR-901047 https://reactome.org/PathwayBrowser/#/R-XTR-901047 Binding of ERp57 IEA Xenopus tropicalis 59080 R-XTR-983145 https://reactome.org/PathwayBrowser/#/R-XTR-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Xenopus tropicalis 59080 R-XTR-983424 https://reactome.org/PathwayBrowser/#/R-XTR-983424 Budding of COPII coated vesicle IEA Xenopus tropicalis 59080 R-XTR-983425 https://reactome.org/PathwayBrowser/#/R-XTR-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Xenopus tropicalis 59081 R-BTA-446189 https://reactome.org/PathwayBrowser/#/R-BTA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Bos taurus 59081 R-BTA-446202 https://reactome.org/PathwayBrowser/#/R-BTA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Bos taurus 59081 R-CEL-446189 https://reactome.org/PathwayBrowser/#/R-CEL-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Caenorhabditis elegans 59081 R-CEL-446202 https://reactome.org/PathwayBrowser/#/R-CEL-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Caenorhabditis elegans 59081 R-CFA-446189 https://reactome.org/PathwayBrowser/#/R-CFA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Canis familiaris 59081 R-CFA-446202 https://reactome.org/PathwayBrowser/#/R-CFA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Canis familiaris 59081 R-DDI-446189 https://reactome.org/PathwayBrowser/#/R-DDI-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Dictyostelium discoideum 59081 R-DDI-446202 https://reactome.org/PathwayBrowser/#/R-DDI-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Dictyostelium discoideum 59081 R-DME-446189 https://reactome.org/PathwayBrowser/#/R-DME-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Drosophila melanogaster 59081 R-DME-446202 https://reactome.org/PathwayBrowser/#/R-DME-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Drosophila melanogaster 59081 R-DRE-446189 https://reactome.org/PathwayBrowser/#/R-DRE-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Danio rerio 59081 R-GGA-446189 https://reactome.org/PathwayBrowser/#/R-GGA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Gallus gallus 59081 R-GGA-446202 https://reactome.org/PathwayBrowser/#/R-GGA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Gallus gallus 59081 R-HSA-446189 https://reactome.org/PathwayBrowser/#/R-HSA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 TAS Homo sapiens 59081 R-HSA-446202 https://reactome.org/PathwayBrowser/#/R-HSA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 TAS Homo sapiens 59081 R-HSA-4724330 https://reactome.org/PathwayBrowser/#/R-HSA-4724330 Defective ALG8 does not add glucose to the N-glycan precursor TAS Homo sapiens 59081 R-MMU-446189 https://reactome.org/PathwayBrowser/#/R-MMU-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Mus musculus 59081 R-MMU-446202 https://reactome.org/PathwayBrowser/#/R-MMU-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Mus musculus 59081 R-RNO-446189 https://reactome.org/PathwayBrowser/#/R-RNO-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Rattus norvegicus 59081 R-RNO-446202 https://reactome.org/PathwayBrowser/#/R-RNO-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Rattus norvegicus 59081 R-SCE-446189 https://reactome.org/PathwayBrowser/#/R-SCE-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Saccharomyces cerevisiae 59081 R-SCE-446202 https://reactome.org/PathwayBrowser/#/R-SCE-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Saccharomyces cerevisiae 59081 R-SPO-446189 https://reactome.org/PathwayBrowser/#/R-SPO-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Schizosaccharomyces pombe 59081 R-SPO-446202 https://reactome.org/PathwayBrowser/#/R-SPO-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Schizosaccharomyces pombe 59081 R-SSC-446189 https://reactome.org/PathwayBrowser/#/R-SSC-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Sus scrofa 59081 R-SSC-446202 https://reactome.org/PathwayBrowser/#/R-SSC-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Sus scrofa 59081 R-XTR-446189 https://reactome.org/PathwayBrowser/#/R-XTR-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Xenopus tropicalis 59081 R-XTR-446202 https://reactome.org/PathwayBrowser/#/R-XTR-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Xenopus tropicalis 59082 R-HSA-532667 https://reactome.org/PathwayBrowser/#/R-HSA-532667 Removal of the second glucose by glucosidase II TAS Homo sapiens 59082 R-HSA-532678 https://reactome.org/PathwayBrowser/#/R-HSA-532678 Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase TAS Homo sapiens 59082 R-HSA-901006 https://reactome.org/PathwayBrowser/#/R-HSA-901006 Binding of Malectin TAS Homo sapiens 59084 R-BTA-964759 https://reactome.org/PathwayBrowser/#/R-BTA-964759 Alternative endo-mannosidase I route IEA Bos taurus 59084 R-CFA-964759 https://reactome.org/PathwayBrowser/#/R-CFA-964759 Alternative endo-mannosidase I route IEA Canis familiaris 59084 R-DME-964759 https://reactome.org/PathwayBrowser/#/R-DME-964759 Alternative endo-mannosidase I route IEA Drosophila melanogaster 59084 R-DRE-964759 https://reactome.org/PathwayBrowser/#/R-DRE-964759 Alternative endo-mannosidase I route IEA Danio rerio 59084 R-GGA-964759 https://reactome.org/PathwayBrowser/#/R-GGA-964759 Alternative endo-mannosidase I route IEA Gallus gallus 59084 R-HSA-446209 https://reactome.org/PathwayBrowser/#/R-HSA-446209 Transfer of N-glycan to the protein TAS Homo sapiens 59084 R-HSA-4793947 https://reactome.org/PathwayBrowser/#/R-HSA-4793947 Defective MOGS does not cleave glucose from an N-glycosylated protein TAS Homo sapiens 59084 R-HSA-532678 https://reactome.org/PathwayBrowser/#/R-HSA-532678 Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase TAS Homo sapiens 59084 R-HSA-964759 https://reactome.org/PathwayBrowser/#/R-HSA-964759 Alternative endo-mannosidase I route TAS Homo sapiens 59084 R-MMU-964759 https://reactome.org/PathwayBrowser/#/R-MMU-964759 Alternative endo-mannosidase I route IEA Mus musculus 59084 R-RNO-964759 https://reactome.org/PathwayBrowser/#/R-RNO-964759 Alternative endo-mannosidase I route IEA Rattus norvegicus 59084 R-SSC-964759 https://reactome.org/PathwayBrowser/#/R-SSC-964759 Alternative endo-mannosidase I route IEA Sus scrofa 59084 R-XTR-964759 https://reactome.org/PathwayBrowser/#/R-XTR-964759 Alternative endo-mannosidase I route IEA Xenopus tropicalis 59085 R-BTA-446208 https://reactome.org/PathwayBrowser/#/R-BTA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Bos taurus 59085 R-CEL-446208 https://reactome.org/PathwayBrowser/#/R-CEL-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Caenorhabditis elegans 59085 R-CFA-446208 https://reactome.org/PathwayBrowser/#/R-CFA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Canis familiaris 59085 R-DDI-446208 https://reactome.org/PathwayBrowser/#/R-DDI-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Dictyostelium discoideum 59085 R-DME-446208 https://reactome.org/PathwayBrowser/#/R-DME-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Drosophila melanogaster 59085 R-GGA-446208 https://reactome.org/PathwayBrowser/#/R-GGA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Gallus gallus 59085 R-HSA-446208 https://reactome.org/PathwayBrowser/#/R-HSA-446208 Addition of a second mannose to the N-glycan precursor by ALG2 TAS Homo sapiens 59085 R-HSA-449718 https://reactome.org/PathwayBrowser/#/R-HSA-449718 Addition of a third mannose to the N-glycan precursor by ALG2 IEA Homo sapiens 59085 R-MMU-446208 https://reactome.org/PathwayBrowser/#/R-MMU-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Mus musculus 59085 R-RNO-446208 https://reactome.org/PathwayBrowser/#/R-RNO-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Rattus norvegicus 59085 R-SCE-446208 https://reactome.org/PathwayBrowser/#/R-SCE-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Saccharomyces cerevisiae 59085 R-SCE-449748 https://reactome.org/PathwayBrowser/#/R-SCE-449748 Addition of a third mannose to the N-glycan precursor by Alg2 TAS Saccharomyces cerevisiae 59085 R-SPO-446208 https://reactome.org/PathwayBrowser/#/R-SPO-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Schizosaccharomyces pombe 59085 R-SSC-446208 https://reactome.org/PathwayBrowser/#/R-SSC-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Sus scrofa 59085 R-XTR-446208 https://reactome.org/PathwayBrowser/#/R-XTR-446208 Addition of a second mannose to the N-glycan precursor by ALG2 IEA Xenopus tropicalis 59087 R-BTA-1022127 https://reactome.org/PathwayBrowser/#/R-BTA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Bos taurus 59087 R-BTA-8850594 https://reactome.org/PathwayBrowser/#/R-BTA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Bos taurus 59087 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 59087 R-BTA-964737 https://reactome.org/PathwayBrowser/#/R-BTA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 59087 R-BTA-964768 https://reactome.org/PathwayBrowser/#/R-BTA-964768 Addition of GlcNAc to the glycan on the A arm IEA Bos taurus 59087 R-BTA-964825 https://reactome.org/PathwayBrowser/#/R-BTA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 59087 R-BTA-964830 https://reactome.org/PathwayBrowser/#/R-BTA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 59087 R-CEL-1022127 https://reactome.org/PathwayBrowser/#/R-CEL-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Caenorhabditis elegans 59087 R-CEL-8850594 https://reactome.org/PathwayBrowser/#/R-CEL-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Caenorhabditis elegans 59087 R-CEL-964737 https://reactome.org/PathwayBrowser/#/R-CEL-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 59087 R-CEL-964768 https://reactome.org/PathwayBrowser/#/R-CEL-964768 Addition of GlcNAc to the glycan on the A arm IEA Caenorhabditis elegans 59087 R-CEL-964825 https://reactome.org/PathwayBrowser/#/R-CEL-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 59087 R-CEL-964830 https://reactome.org/PathwayBrowser/#/R-CEL-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 59087 R-CFA-1022127 https://reactome.org/PathwayBrowser/#/R-CFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Canis familiaris 59087 R-CFA-8850594 https://reactome.org/PathwayBrowser/#/R-CFA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Canis familiaris 59087 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 59087 R-CFA-964737 https://reactome.org/PathwayBrowser/#/R-CFA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 59087 R-CFA-964825 https://reactome.org/PathwayBrowser/#/R-CFA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 59087 R-CFA-964830 https://reactome.org/PathwayBrowser/#/R-CFA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 59087 R-DDI-1022127 https://reactome.org/PathwayBrowser/#/R-DDI-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Dictyostelium discoideum 59087 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 59087 R-DDI-964737 https://reactome.org/PathwayBrowser/#/R-DDI-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 59087 R-DDI-964768 https://reactome.org/PathwayBrowser/#/R-DDI-964768 Addition of GlcNAc to the glycan on the A arm IEA Dictyostelium discoideum 59087 R-DDI-964825 https://reactome.org/PathwayBrowser/#/R-DDI-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 59087 R-DDI-964830 https://reactome.org/PathwayBrowser/#/R-DDI-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 59087 R-DME-1022127 https://reactome.org/PathwayBrowser/#/R-DME-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Drosophila melanogaster 59087 R-DME-8850594 https://reactome.org/PathwayBrowser/#/R-DME-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Drosophila melanogaster 59087 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 59087 R-DME-964737 https://reactome.org/PathwayBrowser/#/R-DME-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 59087 R-DME-964768 https://reactome.org/PathwayBrowser/#/R-DME-964768 Addition of GlcNAc to the glycan on the A arm IEA Drosophila melanogaster 59087 R-DME-964825 https://reactome.org/PathwayBrowser/#/R-DME-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 59087 R-DME-964830 https://reactome.org/PathwayBrowser/#/R-DME-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 59087 R-DRE-1022127 https://reactome.org/PathwayBrowser/#/R-DRE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Danio rerio 59087 R-DRE-8850594 https://reactome.org/PathwayBrowser/#/R-DRE-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Danio rerio 59087 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 59087 R-DRE-964737 https://reactome.org/PathwayBrowser/#/R-DRE-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 59087 R-DRE-964768 https://reactome.org/PathwayBrowser/#/R-DRE-964768 Addition of GlcNAc to the glycan on the A arm IEA Danio rerio 59087 R-DRE-964825 https://reactome.org/PathwayBrowser/#/R-DRE-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 59087 R-DRE-964830 https://reactome.org/PathwayBrowser/#/R-DRE-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 59087 R-GGA-1022127 https://reactome.org/PathwayBrowser/#/R-GGA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Gallus gallus 59087 R-GGA-8850594 https://reactome.org/PathwayBrowser/#/R-GGA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Gallus gallus 59087 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 59087 R-GGA-964737 https://reactome.org/PathwayBrowser/#/R-GGA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 59087 R-GGA-964768 https://reactome.org/PathwayBrowser/#/R-GGA-964768 Addition of GlcNAc to the glycan on the A arm IEA Gallus gallus 59087 R-GGA-964825 https://reactome.org/PathwayBrowser/#/R-GGA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 59087 R-GGA-964830 https://reactome.org/PathwayBrowser/#/R-GGA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 59087 R-HSA-1022127 https://reactome.org/PathwayBrowser/#/R-HSA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol TAS Homo sapiens 59087 R-HSA-6782685 https://reactome.org/PathwayBrowser/#/R-HSA-6782685 EDEM1,3 hydrolyse (GlcNAc)2 (Man)8b to (GlcNAc)2 (Man)5 TAS Homo sapiens 59087 R-HSA-8850594 https://reactome.org/PathwayBrowser/#/R-HSA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins TAS Homo sapiens 59087 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 59087 R-HSA-8867288 https://reactome.org/PathwayBrowser/#/R-HSA-8867288 OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5 TAS Homo sapiens 59087 R-HSA-964737 https://reactome.org/PathwayBrowser/#/R-HSA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 59087 R-HSA-964768 https://reactome.org/PathwayBrowser/#/R-HSA-964768 Addition of GlcNAc to the glycan on the A arm TAS Homo sapiens 59087 R-HSA-964825 https://reactome.org/PathwayBrowser/#/R-HSA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 59087 R-HSA-964830 https://reactome.org/PathwayBrowser/#/R-HSA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 59087 R-MMU-1022127 https://reactome.org/PathwayBrowser/#/R-MMU-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Mus musculus 59087 R-MMU-8850594 https://reactome.org/PathwayBrowser/#/R-MMU-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Mus musculus 59087 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 59087 R-MMU-964737 https://reactome.org/PathwayBrowser/#/R-MMU-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 59087 R-MMU-964768 https://reactome.org/PathwayBrowser/#/R-MMU-964768 Addition of GlcNAc to the glycan on the A arm IEA Mus musculus 59087 R-MMU-964825 https://reactome.org/PathwayBrowser/#/R-MMU-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 59087 R-MMU-964830 https://reactome.org/PathwayBrowser/#/R-MMU-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 59087 R-PFA-1022127 https://reactome.org/PathwayBrowser/#/R-PFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Plasmodium falciparum 59087 R-RNO-1022127 https://reactome.org/PathwayBrowser/#/R-RNO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Rattus norvegicus 59087 R-RNO-8850594 https://reactome.org/PathwayBrowser/#/R-RNO-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Rattus norvegicus 59087 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 59087 R-RNO-964737 https://reactome.org/PathwayBrowser/#/R-RNO-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 59087 R-RNO-964768 https://reactome.org/PathwayBrowser/#/R-RNO-964768 Addition of GlcNAc to the glycan on the A arm IEA Rattus norvegicus 59087 R-RNO-964825 https://reactome.org/PathwayBrowser/#/R-RNO-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 59087 R-RNO-964830 https://reactome.org/PathwayBrowser/#/R-RNO-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 59087 R-SCE-1022127 https://reactome.org/PathwayBrowser/#/R-SCE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Saccharomyces cerevisiae 59087 R-SPO-1022127 https://reactome.org/PathwayBrowser/#/R-SPO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Schizosaccharomyces pombe 59087 R-SSC-1022127 https://reactome.org/PathwayBrowser/#/R-SSC-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Sus scrofa 59087 R-SSC-8850594 https://reactome.org/PathwayBrowser/#/R-SSC-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Sus scrofa 59087 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 59087 R-SSC-964737 https://reactome.org/PathwayBrowser/#/R-SSC-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 59087 R-SSC-964768 https://reactome.org/PathwayBrowser/#/R-SSC-964768 Addition of GlcNAc to the glycan on the A arm IEA Sus scrofa 59087 R-SSC-964825 https://reactome.org/PathwayBrowser/#/R-SSC-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 59087 R-SSC-964830 https://reactome.org/PathwayBrowser/#/R-SSC-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 59087 R-XTR-1022127 https://reactome.org/PathwayBrowser/#/R-XTR-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Xenopus tropicalis 59087 R-XTR-8850594 https://reactome.org/PathwayBrowser/#/R-XTR-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Xenopus tropicalis 59087 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 59087 R-XTR-964737 https://reactome.org/PathwayBrowser/#/R-XTR-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 59087 R-XTR-964768 https://reactome.org/PathwayBrowser/#/R-XTR-964768 Addition of GlcNAc to the glycan on the A arm IEA Xenopus tropicalis 59087 R-XTR-964825 https://reactome.org/PathwayBrowser/#/R-XTR-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 59087 R-XTR-964830 https://reactome.org/PathwayBrowser/#/R-XTR-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 59088 R-BTA-446198 https://reactome.org/PathwayBrowser/#/R-BTA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Bos taurus 59088 R-BTA-446215 https://reactome.org/PathwayBrowser/#/R-BTA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Bos taurus 59088 R-CEL-446198 https://reactome.org/PathwayBrowser/#/R-CEL-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Caenorhabditis elegans 59088 R-CEL-446215 https://reactome.org/PathwayBrowser/#/R-CEL-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Caenorhabditis elegans 59088 R-CFA-446198 https://reactome.org/PathwayBrowser/#/R-CFA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Canis familiaris 59088 R-CFA-446215 https://reactome.org/PathwayBrowser/#/R-CFA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Canis familiaris 59088 R-DDI-446198 https://reactome.org/PathwayBrowser/#/R-DDI-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Dictyostelium discoideum 59088 R-DDI-446215 https://reactome.org/PathwayBrowser/#/R-DDI-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Dictyostelium discoideum 59088 R-DME-446198 https://reactome.org/PathwayBrowser/#/R-DME-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Drosophila melanogaster 59088 R-DME-446215 https://reactome.org/PathwayBrowser/#/R-DME-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Drosophila melanogaster 59088 R-DRE-446198 https://reactome.org/PathwayBrowser/#/R-DRE-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Danio rerio 59088 R-GGA-446198 https://reactome.org/PathwayBrowser/#/R-GGA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Gallus gallus 59088 R-GGA-446215 https://reactome.org/PathwayBrowser/#/R-GGA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Gallus gallus 59088 R-HSA-446198 https://reactome.org/PathwayBrowser/#/R-HSA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 TAS Homo sapiens 59088 R-HSA-446215 https://reactome.org/PathwayBrowser/#/R-HSA-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 TAS Homo sapiens 59088 R-HSA-4686998 https://reactome.org/PathwayBrowser/#/R-HSA-4686998 Defective MPDU1 does not promote transfer of Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 by ALG12 TAS Homo sapiens 59088 R-HSA-4720497 https://reactome.org/PathwayBrowser/#/R-HSA-4720497 Defective ALG12 does not add mannose to the N-glycan precursor TAS Homo sapiens 59088 R-MMU-446198 https://reactome.org/PathwayBrowser/#/R-MMU-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Mus musculus 59088 R-MMU-446215 https://reactome.org/PathwayBrowser/#/R-MMU-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Mus musculus 59088 R-RNO-446198 https://reactome.org/PathwayBrowser/#/R-RNO-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Rattus norvegicus 59088 R-RNO-446215 https://reactome.org/PathwayBrowser/#/R-RNO-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Rattus norvegicus 59088 R-SCE-446198 https://reactome.org/PathwayBrowser/#/R-SCE-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Saccharomyces cerevisiae 59088 R-SCE-446215 https://reactome.org/PathwayBrowser/#/R-SCE-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Saccharomyces cerevisiae 59088 R-SPO-446198 https://reactome.org/PathwayBrowser/#/R-SPO-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Schizosaccharomyces pombe 59088 R-SPO-446215 https://reactome.org/PathwayBrowser/#/R-SPO-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Schizosaccharomyces pombe 59088 R-SSC-446198 https://reactome.org/PathwayBrowser/#/R-SSC-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Sus scrofa 59088 R-SSC-446215 https://reactome.org/PathwayBrowser/#/R-SSC-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Sus scrofa 59088 R-XTR-446215 https://reactome.org/PathwayBrowser/#/R-XTR-446215 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 IEA Xenopus tropicalis 59089 R-BTA-964759 https://reactome.org/PathwayBrowser/#/R-BTA-964759 Alternative endo-mannosidase I route IEA Bos taurus 59089 R-CFA-964759 https://reactome.org/PathwayBrowser/#/R-CFA-964759 Alternative endo-mannosidase I route IEA Canis familiaris 59089 R-DME-964759 https://reactome.org/PathwayBrowser/#/R-DME-964759 Alternative endo-mannosidase I route IEA Drosophila melanogaster 59089 R-DRE-964759 https://reactome.org/PathwayBrowser/#/R-DRE-964759 Alternative endo-mannosidase I route IEA Danio rerio 59089 R-GGA-964759 https://reactome.org/PathwayBrowser/#/R-GGA-964759 Alternative endo-mannosidase I route IEA Gallus gallus 59089 R-HSA-964759 https://reactome.org/PathwayBrowser/#/R-HSA-964759 Alternative endo-mannosidase I route TAS Homo sapiens 59089 R-MMU-964759 https://reactome.org/PathwayBrowser/#/R-MMU-964759 Alternative endo-mannosidase I route IEA Mus musculus 59089 R-RNO-964759 https://reactome.org/PathwayBrowser/#/R-RNO-964759 Alternative endo-mannosidase I route IEA Rattus norvegicus 59089 R-SSC-964759 https://reactome.org/PathwayBrowser/#/R-SSC-964759 Alternative endo-mannosidase I route IEA Sus scrofa 59089 R-XTR-964759 https://reactome.org/PathwayBrowser/#/R-XTR-964759 Alternative endo-mannosidase I route IEA Xenopus tropicalis 59091 R-BTA-446198 https://reactome.org/PathwayBrowser/#/R-BTA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Bos taurus 59091 R-BTA-446216 https://reactome.org/PathwayBrowser/#/R-BTA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Bos taurus 59091 R-CEL-446198 https://reactome.org/PathwayBrowser/#/R-CEL-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Caenorhabditis elegans 59091 R-CEL-446216 https://reactome.org/PathwayBrowser/#/R-CEL-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Caenorhabditis elegans 59091 R-CFA-446198 https://reactome.org/PathwayBrowser/#/R-CFA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Canis familiaris 59091 R-CFA-446216 https://reactome.org/PathwayBrowser/#/R-CFA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Canis familiaris 59091 R-DDI-446198 https://reactome.org/PathwayBrowser/#/R-DDI-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Dictyostelium discoideum 59091 R-DDI-446216 https://reactome.org/PathwayBrowser/#/R-DDI-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Dictyostelium discoideum 59091 R-DME-446198 https://reactome.org/PathwayBrowser/#/R-DME-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Drosophila melanogaster 59091 R-DME-446216 https://reactome.org/PathwayBrowser/#/R-DME-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Drosophila melanogaster 59091 R-DRE-446198 https://reactome.org/PathwayBrowser/#/R-DRE-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Danio rerio 59091 R-GGA-446198 https://reactome.org/PathwayBrowser/#/R-GGA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Gallus gallus 59091 R-GGA-446216 https://reactome.org/PathwayBrowser/#/R-GGA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Gallus gallus 59091 R-HSA-446198 https://reactome.org/PathwayBrowser/#/R-HSA-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 TAS Homo sapiens 59091 R-HSA-446216 https://reactome.org/PathwayBrowser/#/R-HSA-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 TAS Homo sapiens 59091 R-HSA-9035514 https://reactome.org/PathwayBrowser/#/R-HSA-9035514 Defective ALG9 does not add the last mannose to the N-glycan precursor TAS Homo sapiens 59091 R-HSA-9036020 https://reactome.org/PathwayBrowser/#/R-HSA-9036020 Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)8 (PP-Dol)1 by ALG9 TAS Homo sapiens 59091 R-MMU-446198 https://reactome.org/PathwayBrowser/#/R-MMU-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Mus musculus 59091 R-MMU-446216 https://reactome.org/PathwayBrowser/#/R-MMU-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Mus musculus 59091 R-RNO-446198 https://reactome.org/PathwayBrowser/#/R-RNO-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Rattus norvegicus 59091 R-RNO-446216 https://reactome.org/PathwayBrowser/#/R-RNO-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Rattus norvegicus 59091 R-SCE-446198 https://reactome.org/PathwayBrowser/#/R-SCE-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Saccharomyces cerevisiae 59091 R-SCE-446216 https://reactome.org/PathwayBrowser/#/R-SCE-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Saccharomyces cerevisiae 59091 R-SPO-446198 https://reactome.org/PathwayBrowser/#/R-SPO-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Schizosaccharomyces pombe 59091 R-SPO-446216 https://reactome.org/PathwayBrowser/#/R-SPO-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Schizosaccharomyces pombe 59091 R-SSC-446198 https://reactome.org/PathwayBrowser/#/R-SSC-446198 ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 IEA Sus scrofa 59091 R-SSC-446216 https://reactome.org/PathwayBrowser/#/R-SSC-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Sus scrofa 59091 R-XTR-446216 https://reactome.org/PathwayBrowser/#/R-XTR-446216 ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 IEA Xenopus tropicalis 59092 R-BTA-1022127 https://reactome.org/PathwayBrowser/#/R-BTA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Bos taurus 59092 R-BTA-8850594 https://reactome.org/PathwayBrowser/#/R-BTA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Bos taurus 59092 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 59092 R-BTA-964737 https://reactome.org/PathwayBrowser/#/R-BTA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 59092 R-CEL-1022127 https://reactome.org/PathwayBrowser/#/R-CEL-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Caenorhabditis elegans 59092 R-CEL-8850594 https://reactome.org/PathwayBrowser/#/R-CEL-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Caenorhabditis elegans 59092 R-CEL-964737 https://reactome.org/PathwayBrowser/#/R-CEL-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 59092 R-CFA-1022127 https://reactome.org/PathwayBrowser/#/R-CFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Canis familiaris 59092 R-CFA-8850594 https://reactome.org/PathwayBrowser/#/R-CFA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Canis familiaris 59092 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 59092 R-CFA-964737 https://reactome.org/PathwayBrowser/#/R-CFA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 59092 R-DDI-1022127 https://reactome.org/PathwayBrowser/#/R-DDI-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Dictyostelium discoideum 59092 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 59092 R-DDI-964737 https://reactome.org/PathwayBrowser/#/R-DDI-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 59092 R-DME-1022127 https://reactome.org/PathwayBrowser/#/R-DME-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Drosophila melanogaster 59092 R-DME-8850594 https://reactome.org/PathwayBrowser/#/R-DME-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Drosophila melanogaster 59092 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 59092 R-DME-964737 https://reactome.org/PathwayBrowser/#/R-DME-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 59092 R-DRE-1022127 https://reactome.org/PathwayBrowser/#/R-DRE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Danio rerio 59092 R-DRE-8850594 https://reactome.org/PathwayBrowser/#/R-DRE-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Danio rerio 59092 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 59092 R-DRE-964737 https://reactome.org/PathwayBrowser/#/R-DRE-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 59092 R-GGA-1022127 https://reactome.org/PathwayBrowser/#/R-GGA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Gallus gallus 59092 R-GGA-8850594 https://reactome.org/PathwayBrowser/#/R-GGA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Gallus gallus 59092 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 59092 R-GGA-964737 https://reactome.org/PathwayBrowser/#/R-GGA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 59092 R-HSA-1022127 https://reactome.org/PathwayBrowser/#/R-HSA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol TAS Homo sapiens 59092 R-HSA-4793949 https://reactome.org/PathwayBrowser/#/R-HSA-4793949 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (a branch) TAS Homo sapiens 59092 R-HSA-548890 https://reactome.org/PathwayBrowser/#/R-HSA-548890 Removal of the third glucose by glucosidase II and release from the chaperone TAS Homo sapiens 59092 R-HSA-8850594 https://reactome.org/PathwayBrowser/#/R-HSA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins TAS Homo sapiens 59092 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 59092 R-HSA-8867288 https://reactome.org/PathwayBrowser/#/R-HSA-8867288 OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5 TAS Homo sapiens 59092 R-HSA-901024 https://reactome.org/PathwayBrowser/#/R-HSA-901024 MAN1B1 hydrolyses 1,2-linked mannose (a branch) TAS Homo sapiens 59092 R-HSA-901039 https://reactome.org/PathwayBrowser/#/R-HSA-901039 MAN1B1 hydrolyses 1,2-linked mannose (c branch) TAS Homo sapiens 59092 R-HSA-901074 https://reactome.org/PathwayBrowser/#/R-HSA-901074 MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch) TAS Homo sapiens 59092 R-HSA-9036011 https://reactome.org/PathwayBrowser/#/R-HSA-9036011 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (b branch) TAS Homo sapiens 59092 R-HSA-9036012 https://reactome.org/PathwayBrowser/#/R-HSA-9036012 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (c branch) TAS Homo sapiens 59092 R-HSA-912291 https://reactome.org/PathwayBrowser/#/R-HSA-912291 Incorrectly folded glycoproteins translocate to the ERQC TAS Homo sapiens 59092 R-HSA-915148 https://reactome.org/PathwayBrowser/#/R-HSA-915148 Correctly folded glycoproteins translocate to the Golgi TAS Homo sapiens 59092 R-HSA-964737 https://reactome.org/PathwayBrowser/#/R-HSA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 59092 R-MMU-1022127 https://reactome.org/PathwayBrowser/#/R-MMU-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Mus musculus 59092 R-MMU-8850594 https://reactome.org/PathwayBrowser/#/R-MMU-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Mus musculus 59092 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 59092 R-MMU-964737 https://reactome.org/PathwayBrowser/#/R-MMU-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 59092 R-PFA-1022127 https://reactome.org/PathwayBrowser/#/R-PFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Plasmodium falciparum 59092 R-RNO-1022127 https://reactome.org/PathwayBrowser/#/R-RNO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Rattus norvegicus 59092 R-RNO-8850594 https://reactome.org/PathwayBrowser/#/R-RNO-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Rattus norvegicus 59092 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 59092 R-RNO-964737 https://reactome.org/PathwayBrowser/#/R-RNO-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 59092 R-SCE-1022127 https://reactome.org/PathwayBrowser/#/R-SCE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Saccharomyces cerevisiae 59092 R-SPO-1022127 https://reactome.org/PathwayBrowser/#/R-SPO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Schizosaccharomyces pombe 59092 R-SSC-1022127 https://reactome.org/PathwayBrowser/#/R-SSC-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Sus scrofa 59092 R-SSC-8850594 https://reactome.org/PathwayBrowser/#/R-SSC-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Sus scrofa 59092 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 59092 R-SSC-964737 https://reactome.org/PathwayBrowser/#/R-SSC-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 59092 R-XTR-1022127 https://reactome.org/PathwayBrowser/#/R-XTR-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Xenopus tropicalis 59092 R-XTR-8850594 https://reactome.org/PathwayBrowser/#/R-XTR-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Xenopus tropicalis 59092 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 59092 R-XTR-964737 https://reactome.org/PathwayBrowser/#/R-XTR-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 59173 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 59173 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 59173 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 59173 R-BTA-9603302 https://reactome.org/PathwayBrowser/#/R-BTA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Bos taurus 59173 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 59173 R-CFA-9603302 https://reactome.org/PathwayBrowser/#/R-CFA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Canis familiaris 59173 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 59173 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 59173 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 59173 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 59173 R-GGA-9603302 https://reactome.org/PathwayBrowser/#/R-GGA-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Gallus gallus 59173 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 59173 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 59173 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 59173 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 59173 R-HSA-9603302 https://reactome.org/PathwayBrowser/#/R-HSA-9603302 Factor IIa inhibitors (peptide) binds IIa TAS Homo sapiens 59173 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 59173 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 59173 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 59173 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 59173 R-MMU-9603302 https://reactome.org/PathwayBrowser/#/R-MMU-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Mus musculus 59173 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 59173 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 59173 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 59173 R-RNO-9603302 https://reactome.org/PathwayBrowser/#/R-RNO-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Rattus norvegicus 59173 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 59173 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 59173 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 59173 R-SSC-9603302 https://reactome.org/PathwayBrowser/#/R-SSC-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Sus scrofa 59173 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 59173 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 59173 R-XTR-9603302 https://reactome.org/PathwayBrowser/#/R-XTR-9603302 Factor IIa inhibitors (peptide) binds IIa IEA Xenopus tropicalis 59228 R-BTA-8850326 https://reactome.org/PathwayBrowser/#/R-BTA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Bos taurus 59228 R-GGA-8850326 https://reactome.org/PathwayBrowser/#/R-GGA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Gallus gallus 59228 R-HSA-8850326 https://reactome.org/PathwayBrowser/#/R-HSA-8850326 TCR binds self-lipid-based antigen via CD1 TAS Homo sapiens 59228 R-SSC-8850326 https://reactome.org/PathwayBrowser/#/R-SSC-8850326 TCR binds self-lipid-based antigen via CD1 IEA Sus scrofa 59235 R-BTA-8850356 https://reactome.org/PathwayBrowser/#/R-BTA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Bos taurus 59235 R-GGA-8850356 https://reactome.org/PathwayBrowser/#/R-GGA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Gallus gallus 59235 R-HSA-8850356 https://reactome.org/PathwayBrowser/#/R-HSA-8850356 TCR binds microbial lipid-based antigen via CD1 TAS Homo sapiens 59235 R-SSC-8850356 https://reactome.org/PathwayBrowser/#/R-SSC-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Sus scrofa 59240 R-MTU-9635440 https://reactome.org/PathwayBrowser/#/R-MTU-9635440 PapA5 transforms mycocerosyl to PDIM TAS Mycobacterium tuberculosis 59254 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 59254 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 59254 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 59254 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 59254 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 59254 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 59254 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 59254 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 59254 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 59254 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 59254 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 59254 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 59254 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 59254 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 59254 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 59254 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 59254 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 59254 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 59254 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 59254 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 59254 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 59254 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 59254 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 59254 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 59254 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 59254 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 59254 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 59254 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 59254 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 59254 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 59254 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 59254 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 59254 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 59254 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 59254 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 59254 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 59254 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 59271 R-CFA-168400 https://reactome.org/PathwayBrowser/#/R-CFA-168400 iE-DAP elicits a NOD1 response IEA Canis familiaris 59271 R-CFA-168405 https://reactome.org/PathwayBrowser/#/R-CFA-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Canis familiaris 59271 R-CFA-450337 https://reactome.org/PathwayBrowser/#/R-CFA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Canis familiaris 59271 R-CFA-450346 https://reactome.org/PathwayBrowser/#/R-CFA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Canis familiaris 59271 R-CFA-622310 https://reactome.org/PathwayBrowser/#/R-CFA-622310 Activated NOD1 oligomerizes IEA Canis familiaris 59271 R-CFA-622415 https://reactome.org/PathwayBrowser/#/R-CFA-622415 RIP2 binds NEMO IEA Canis familiaris 59271 R-CFA-622420 https://reactome.org/PathwayBrowser/#/R-CFA-622420 NOD1 induced apoptosis is mediated by RIP2 and CARD8 IEA Canis familiaris 59271 R-CFA-688136 https://reactome.org/PathwayBrowser/#/R-CFA-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Canis familiaris 59271 R-CFA-688137 https://reactome.org/PathwayBrowser/#/R-CFA-688137 RIP2 is K63 polyubiquitinated IEA Canis familiaris 59271 R-CFA-688985 https://reactome.org/PathwayBrowser/#/R-CFA-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Canis familiaris 59271 R-CFA-706479 https://reactome.org/PathwayBrowser/#/R-CFA-706479 TAK1 is activated IEA Canis familiaris 59271 R-CFA-741386 https://reactome.org/PathwayBrowser/#/R-CFA-741386 RIP2 induces K63-linked ubiquitination of NEMO IEA Canis familiaris 59271 R-CFA-741411 https://reactome.org/PathwayBrowser/#/R-CFA-741411 CYLD deubiquitinates NEMO IEA Canis familiaris 59271 R-DDI-168400 https://reactome.org/PathwayBrowser/#/R-DDI-168400 iE-DAP elicits a NOD1 response IEA Dictyostelium discoideum 59271 R-DDI-622310 https://reactome.org/PathwayBrowser/#/R-DDI-622310 Activated NOD1 oligomerizes IEA Dictyostelium discoideum 59271 R-HSA-168184 https://reactome.org/PathwayBrowser/#/R-HSA-168184 Activated TAK1 mediates phosphorylation of the IKK Complex TAS Homo sapiens 59271 R-HSA-168400 https://reactome.org/PathwayBrowser/#/R-HSA-168400 iE-DAP elicits a NOD1 response TAS Homo sapiens 59271 R-HSA-168405 https://reactome.org/PathwayBrowser/#/R-HSA-168405 Activated NOD oligomer recruites RIP2 (RICK) TAS Homo sapiens 59271 R-HSA-450337 https://reactome.org/PathwayBrowser/#/R-HSA-450337 Activated TAK1 phosphorylates MKK4/MKK7 TAS Homo sapiens 59271 R-HSA-450346 https://reactome.org/PathwayBrowser/#/R-HSA-450346 activated human TAK1 phosphorylates MKK3/MKK6 TAS Homo sapiens 59271 R-HSA-622310 https://reactome.org/PathwayBrowser/#/R-HSA-622310 Activated NOD1 oligomerizes TAS Homo sapiens 59271 R-HSA-622415 https://reactome.org/PathwayBrowser/#/R-HSA-622415 RIP2 binds NEMO TAS Homo sapiens 59271 R-HSA-622420 https://reactome.org/PathwayBrowser/#/R-HSA-622420 NOD1 induced apoptosis is mediated by RIP2 and CARD8 TAS Homo sapiens 59271 R-HSA-688136 https://reactome.org/PathwayBrowser/#/R-HSA-688136 TNFAIP3 (A20) deubiquitinates RIP2 TAS Homo sapiens 59271 R-HSA-688137 https://reactome.org/PathwayBrowser/#/R-HSA-688137 RIP2 is K63 polyubiquitinated TAS Homo sapiens 59271 R-HSA-688985 https://reactome.org/PathwayBrowser/#/R-HSA-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex TAS Homo sapiens 59271 R-HSA-706479 https://reactome.org/PathwayBrowser/#/R-HSA-706479 TAK1 is activated TAS Homo sapiens 59271 R-HSA-741386 https://reactome.org/PathwayBrowser/#/R-HSA-741386 RIP2 induces K63-linked ubiquitination of NEMO TAS Homo sapiens 59271 R-HSA-741395 https://reactome.org/PathwayBrowser/#/R-HSA-741395 CARD9 binds RIP2 (and NOD2) IEA Homo sapiens 59271 R-HSA-741411 https://reactome.org/PathwayBrowser/#/R-HSA-741411 CYLD deubiquitinates NEMO TAS Homo sapiens 59271 R-MMU-168400 https://reactome.org/PathwayBrowser/#/R-MMU-168400 iE-DAP elicits a NOD1 response IEA Mus musculus 59271 R-MMU-168405 https://reactome.org/PathwayBrowser/#/R-MMU-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Mus musculus 59271 R-MMU-450337 https://reactome.org/PathwayBrowser/#/R-MMU-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Mus musculus 59271 R-MMU-450346 https://reactome.org/PathwayBrowser/#/R-MMU-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Mus musculus 59271 R-MMU-622310 https://reactome.org/PathwayBrowser/#/R-MMU-622310 Activated NOD1 oligomerizes IEA Mus musculus 59271 R-MMU-622415 https://reactome.org/PathwayBrowser/#/R-MMU-622415 RIP2 binds NEMO IEA Mus musculus 59271 R-MMU-622420 https://reactome.org/PathwayBrowser/#/R-MMU-622420 NOD1 induced apoptosis is mediated by RIP2 and CARD8 IEA Mus musculus 59271 R-MMU-688136 https://reactome.org/PathwayBrowser/#/R-MMU-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Mus musculus 59271 R-MMU-688137 https://reactome.org/PathwayBrowser/#/R-MMU-688137 RIP2 is K63 polyubiquitinated IEA Mus musculus 59271 R-MMU-688985 https://reactome.org/PathwayBrowser/#/R-MMU-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Mus musculus 59271 R-MMU-706479 https://reactome.org/PathwayBrowser/#/R-MMU-706479 TAK1 is activated IEA Mus musculus 59271 R-MMU-741386 https://reactome.org/PathwayBrowser/#/R-MMU-741386 RIP2 induces K63-linked ubiquitination of NEMO IEA Mus musculus 59271 R-MMU-741411 https://reactome.org/PathwayBrowser/#/R-MMU-741411 CYLD deubiquitinates NEMO IEA Mus musculus 59271 R-RNO-168400 https://reactome.org/PathwayBrowser/#/R-RNO-168400 iE-DAP elicits a NOD1 response IEA Rattus norvegicus 59271 R-RNO-168405 https://reactome.org/PathwayBrowser/#/R-RNO-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Rattus norvegicus 59271 R-RNO-450337 https://reactome.org/PathwayBrowser/#/R-RNO-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Rattus norvegicus 59271 R-RNO-450346 https://reactome.org/PathwayBrowser/#/R-RNO-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Rattus norvegicus 59271 R-RNO-622310 https://reactome.org/PathwayBrowser/#/R-RNO-622310 Activated NOD1 oligomerizes IEA Rattus norvegicus 59271 R-RNO-622415 https://reactome.org/PathwayBrowser/#/R-RNO-622415 RIP2 binds NEMO IEA Rattus norvegicus 59271 R-RNO-622420 https://reactome.org/PathwayBrowser/#/R-RNO-622420 NOD1 induced apoptosis is mediated by RIP2 and CARD8 IEA Rattus norvegicus 59271 R-RNO-688136 https://reactome.org/PathwayBrowser/#/R-RNO-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Rattus norvegicus 59271 R-RNO-688137 https://reactome.org/PathwayBrowser/#/R-RNO-688137 RIP2 is K63 polyubiquitinated IEA Rattus norvegicus 59271 R-RNO-688985 https://reactome.org/PathwayBrowser/#/R-RNO-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Rattus norvegicus 59271 R-RNO-706479 https://reactome.org/PathwayBrowser/#/R-RNO-706479 TAK1 is activated IEA Rattus norvegicus 59271 R-RNO-741411 https://reactome.org/PathwayBrowser/#/R-RNO-741411 CYLD deubiquitinates NEMO IEA Rattus norvegicus 59271 R-XTR-168400 https://reactome.org/PathwayBrowser/#/R-XTR-168400 iE-DAP elicits a NOD1 response IEA Xenopus tropicalis 59271 R-XTR-168405 https://reactome.org/PathwayBrowser/#/R-XTR-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Xenopus tropicalis 59271 R-XTR-450337 https://reactome.org/PathwayBrowser/#/R-XTR-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Xenopus tropicalis 59271 R-XTR-450346 https://reactome.org/PathwayBrowser/#/R-XTR-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Xenopus tropicalis 59271 R-XTR-622310 https://reactome.org/PathwayBrowser/#/R-XTR-622310 Activated NOD1 oligomerizes IEA Xenopus tropicalis 59271 R-XTR-622415 https://reactome.org/PathwayBrowser/#/R-XTR-622415 RIP2 binds NEMO IEA Xenopus tropicalis 59271 R-XTR-688137 https://reactome.org/PathwayBrowser/#/R-XTR-688137 RIP2 is K63 polyubiquitinated IEA Xenopus tropicalis 59271 R-XTR-688985 https://reactome.org/PathwayBrowser/#/R-XTR-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Xenopus tropicalis 59271 R-XTR-706479 https://reactome.org/PathwayBrowser/#/R-XTR-706479 TAK1 is activated IEA Xenopus tropicalis 59338 R-BTA-2161187 https://reactome.org/PathwayBrowser/#/R-BTA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Bos taurus 59338 R-BTA-9731661 https://reactome.org/PathwayBrowser/#/R-BTA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Bos taurus 59338 R-CEL-2161187 https://reactome.org/PathwayBrowser/#/R-CEL-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Caenorhabditis elegans 59338 R-CEL-9731661 https://reactome.org/PathwayBrowser/#/R-CEL-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Caenorhabditis elegans 59338 R-CFA-2161187 https://reactome.org/PathwayBrowser/#/R-CFA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Canis familiaris 59338 R-CFA-9731661 https://reactome.org/PathwayBrowser/#/R-CFA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Canis familiaris 59338 R-DME-2161187 https://reactome.org/PathwayBrowser/#/R-DME-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Drosophila melanogaster 59338 R-DME-9731661 https://reactome.org/PathwayBrowser/#/R-DME-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Drosophila melanogaster 59338 R-DRE-2161187 https://reactome.org/PathwayBrowser/#/R-DRE-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Danio rerio 59338 R-DRE-9731661 https://reactome.org/PathwayBrowser/#/R-DRE-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Danio rerio 59338 R-GGA-2161187 https://reactome.org/PathwayBrowser/#/R-GGA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Gallus gallus 59338 R-GGA-9731661 https://reactome.org/PathwayBrowser/#/R-GGA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Gallus gallus 59338 R-HSA-2161187 https://reactome.org/PathwayBrowser/#/R-HSA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine TAS Homo sapiens 59338 R-HSA-9731661 https://reactome.org/PathwayBrowser/#/R-HSA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine TAS Homo sapiens 59338 R-MMU-2161187 https://reactome.org/PathwayBrowser/#/R-MMU-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Mus musculus 59338 R-MMU-9731661 https://reactome.org/PathwayBrowser/#/R-MMU-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Mus musculus 59338 R-SSC-2161187 https://reactome.org/PathwayBrowser/#/R-SSC-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Sus scrofa 59338 R-SSC-9731661 https://reactome.org/PathwayBrowser/#/R-SSC-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Sus scrofa 59338 R-XTR-2161187 https://reactome.org/PathwayBrowser/#/R-XTR-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Xenopus tropicalis 59338 R-XTR-9731661 https://reactome.org/PathwayBrowser/#/R-XTR-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Xenopus tropicalis 59414 R-BTA-168405 https://reactome.org/PathwayBrowser/#/R-BTA-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Bos taurus 59414 R-BTA-168412 https://reactome.org/PathwayBrowser/#/R-BTA-168412 MDP elicits a NOD2 response IEA Bos taurus 59414 R-BTA-450337 https://reactome.org/PathwayBrowser/#/R-BTA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Bos taurus 59414 R-BTA-450346 https://reactome.org/PathwayBrowser/#/R-BTA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Bos taurus 59414 R-BTA-622415 https://reactome.org/PathwayBrowser/#/R-BTA-622415 RIP2 binds NEMO IEA Bos taurus 59414 R-BTA-688136 https://reactome.org/PathwayBrowser/#/R-BTA-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Bos taurus 59414 R-BTA-688137 https://reactome.org/PathwayBrowser/#/R-BTA-688137 RIP2 is K63 polyubiquitinated IEA Bos taurus 59414 R-BTA-688985 https://reactome.org/PathwayBrowser/#/R-BTA-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Bos taurus 59414 R-BTA-706479 https://reactome.org/PathwayBrowser/#/R-BTA-706479 TAK1 is activated IEA Bos taurus 59414 R-BTA-708349 https://reactome.org/PathwayBrowser/#/R-BTA-708349 Activated NOD2 oligomerizes IEA Bos taurus 59414 R-BTA-741411 https://reactome.org/PathwayBrowser/#/R-BTA-741411 CYLD deubiquitinates NEMO IEA Bos taurus 59414 R-BTA-844438 https://reactome.org/PathwayBrowser/#/R-BTA-844438 NLRP1 oligomerizes IEA Bos taurus 59414 R-BTA-844447 https://reactome.org/PathwayBrowser/#/R-BTA-844447 NLRP1 senses MDP IEA Bos taurus 59414 R-BTA-879222 https://reactome.org/PathwayBrowser/#/R-BTA-879222 MDP:NLRP1 binds ATP IEA Bos taurus 59414 R-CFA-168405 https://reactome.org/PathwayBrowser/#/R-CFA-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Canis familiaris 59414 R-CFA-168412 https://reactome.org/PathwayBrowser/#/R-CFA-168412 MDP elicits a NOD2 response IEA Canis familiaris 59414 R-CFA-450337 https://reactome.org/PathwayBrowser/#/R-CFA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Canis familiaris 59414 R-CFA-450346 https://reactome.org/PathwayBrowser/#/R-CFA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Canis familiaris 59414 R-CFA-622415 https://reactome.org/PathwayBrowser/#/R-CFA-622415 RIP2 binds NEMO IEA Canis familiaris 59414 R-CFA-688136 https://reactome.org/PathwayBrowser/#/R-CFA-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Canis familiaris 59414 R-CFA-688137 https://reactome.org/PathwayBrowser/#/R-CFA-688137 RIP2 is K63 polyubiquitinated IEA Canis familiaris 59414 R-CFA-688985 https://reactome.org/PathwayBrowser/#/R-CFA-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Canis familiaris 59414 R-CFA-706479 https://reactome.org/PathwayBrowser/#/R-CFA-706479 TAK1 is activated IEA Canis familiaris 59414 R-CFA-708349 https://reactome.org/PathwayBrowser/#/R-CFA-708349 Activated NOD2 oligomerizes IEA Canis familiaris 59414 R-CFA-741386 https://reactome.org/PathwayBrowser/#/R-CFA-741386 RIP2 induces K63-linked ubiquitination of NEMO IEA Canis familiaris 59414 R-CFA-741411 https://reactome.org/PathwayBrowser/#/R-CFA-741411 CYLD deubiquitinates NEMO IEA Canis familiaris 59414 R-CFA-844438 https://reactome.org/PathwayBrowser/#/R-CFA-844438 NLRP1 oligomerizes IEA Canis familiaris 59414 R-CFA-844447 https://reactome.org/PathwayBrowser/#/R-CFA-844447 NLRP1 senses MDP IEA Canis familiaris 59414 R-CFA-879222 https://reactome.org/PathwayBrowser/#/R-CFA-879222 MDP:NLRP1 binds ATP IEA Canis familiaris 59414 R-DDI-168412 https://reactome.org/PathwayBrowser/#/R-DDI-168412 MDP elicits a NOD2 response IEA Dictyostelium discoideum 59414 R-DDI-708349 https://reactome.org/PathwayBrowser/#/R-DDI-708349 Activated NOD2 oligomerizes IEA Dictyostelium discoideum 59414 R-DRE-168405 https://reactome.org/PathwayBrowser/#/R-DRE-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Danio rerio 59414 R-DRE-168412 https://reactome.org/PathwayBrowser/#/R-DRE-168412 MDP elicits a NOD2 response IEA Danio rerio 59414 R-DRE-622415 https://reactome.org/PathwayBrowser/#/R-DRE-622415 RIP2 binds NEMO IEA Danio rerio 59414 R-DRE-688137 https://reactome.org/PathwayBrowser/#/R-DRE-688137 RIP2 is K63 polyubiquitinated IEA Danio rerio 59414 R-DRE-708349 https://reactome.org/PathwayBrowser/#/R-DRE-708349 Activated NOD2 oligomerizes IEA Danio rerio 59414 R-DRE-741386 https://reactome.org/PathwayBrowser/#/R-DRE-741386 RIP2 induces K63-linked ubiquitination of NEMO IEA Danio rerio 59414 R-DRE-741411 https://reactome.org/PathwayBrowser/#/R-DRE-741411 CYLD deubiquitinates NEMO IEA Danio rerio 59414 R-DRE-844438 https://reactome.org/PathwayBrowser/#/R-DRE-844438 NLRP1 oligomerizes IEA Danio rerio 59414 R-DRE-844447 https://reactome.org/PathwayBrowser/#/R-DRE-844447 NLRP1 senses MDP IEA Danio rerio 59414 R-DRE-879222 https://reactome.org/PathwayBrowser/#/R-DRE-879222 MDP:NLRP1 binds ATP IEA Danio rerio 59414 R-GGA-844438 https://reactome.org/PathwayBrowser/#/R-GGA-844438 NLRP1 oligomerizes IEA Gallus gallus 59414 R-GGA-844447 https://reactome.org/PathwayBrowser/#/R-GGA-844447 NLRP1 senses MDP IEA Gallus gallus 59414 R-GGA-879222 https://reactome.org/PathwayBrowser/#/R-GGA-879222 MDP:NLRP1 binds ATP IEA Gallus gallus 59414 R-HSA-168184 https://reactome.org/PathwayBrowser/#/R-HSA-168184 Activated TAK1 mediates phosphorylation of the IKK Complex TAS Homo sapiens 59414 R-HSA-168405 https://reactome.org/PathwayBrowser/#/R-HSA-168405 Activated NOD oligomer recruites RIP2 (RICK) TAS Homo sapiens 59414 R-HSA-168412 https://reactome.org/PathwayBrowser/#/R-HSA-168412 MDP elicits a NOD2 response TAS Homo sapiens 59414 R-HSA-450337 https://reactome.org/PathwayBrowser/#/R-HSA-450337 Activated TAK1 phosphorylates MKK4/MKK7 TAS Homo sapiens 59414 R-HSA-450346 https://reactome.org/PathwayBrowser/#/R-HSA-450346 activated human TAK1 phosphorylates MKK3/MKK6 TAS Homo sapiens 59414 R-HSA-622415 https://reactome.org/PathwayBrowser/#/R-HSA-622415 RIP2 binds NEMO TAS Homo sapiens 59414 R-HSA-688136 https://reactome.org/PathwayBrowser/#/R-HSA-688136 TNFAIP3 (A20) deubiquitinates RIP2 TAS Homo sapiens 59414 R-HSA-688137 https://reactome.org/PathwayBrowser/#/R-HSA-688137 RIP2 is K63 polyubiquitinated TAS Homo sapiens 59414 R-HSA-688985 https://reactome.org/PathwayBrowser/#/R-HSA-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex TAS Homo sapiens 59414 R-HSA-706479 https://reactome.org/PathwayBrowser/#/R-HSA-706479 TAK1 is activated TAS Homo sapiens 59414 R-HSA-708349 https://reactome.org/PathwayBrowser/#/R-HSA-708349 Activated NOD2 oligomerizes TAS Homo sapiens 59414 R-HSA-741386 https://reactome.org/PathwayBrowser/#/R-HSA-741386 RIP2 induces K63-linked ubiquitination of NEMO TAS Homo sapiens 59414 R-HSA-741395 https://reactome.org/PathwayBrowser/#/R-HSA-741395 CARD9 binds RIP2 (and NOD2) IEA Homo sapiens 59414 R-HSA-741411 https://reactome.org/PathwayBrowser/#/R-HSA-741411 CYLD deubiquitinates NEMO TAS Homo sapiens 59414 R-HSA-844438 https://reactome.org/PathwayBrowser/#/R-HSA-844438 NLRP1 oligomerizes TAS Homo sapiens 59414 R-HSA-844447 https://reactome.org/PathwayBrowser/#/R-HSA-844447 NLRP1 senses MDP TAS Homo sapiens 59414 R-HSA-879222 https://reactome.org/PathwayBrowser/#/R-HSA-879222 MDP:NLRP1 binds ATP TAS Homo sapiens 59414 R-MMU-168405 https://reactome.org/PathwayBrowser/#/R-MMU-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Mus musculus 59414 R-MMU-168412 https://reactome.org/PathwayBrowser/#/R-MMU-168412 MDP elicits a NOD2 response IEA Mus musculus 59414 R-MMU-450337 https://reactome.org/PathwayBrowser/#/R-MMU-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Mus musculus 59414 R-MMU-450346 https://reactome.org/PathwayBrowser/#/R-MMU-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Mus musculus 59414 R-MMU-622415 https://reactome.org/PathwayBrowser/#/R-MMU-622415 RIP2 binds NEMO IEA Mus musculus 59414 R-MMU-688136 https://reactome.org/PathwayBrowser/#/R-MMU-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Mus musculus 59414 R-MMU-688137 https://reactome.org/PathwayBrowser/#/R-MMU-688137 RIP2 is K63 polyubiquitinated IEA Mus musculus 59414 R-MMU-688985 https://reactome.org/PathwayBrowser/#/R-MMU-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Mus musculus 59414 R-MMU-706479 https://reactome.org/PathwayBrowser/#/R-MMU-706479 TAK1 is activated IEA Mus musculus 59414 R-MMU-708349 https://reactome.org/PathwayBrowser/#/R-MMU-708349 Activated NOD2 oligomerizes IEA Mus musculus 59414 R-MMU-741383 https://reactome.org/PathwayBrowser/#/R-MMU-741383 Card9 binds Rip2 (and Nod2) TAS Mus musculus 59414 R-MMU-741386 https://reactome.org/PathwayBrowser/#/R-MMU-741386 RIP2 induces K63-linked ubiquitination of NEMO IEA Mus musculus 59414 R-MMU-741411 https://reactome.org/PathwayBrowser/#/R-MMU-741411 CYLD deubiquitinates NEMO IEA Mus musculus 59414 R-MMU-844438 https://reactome.org/PathwayBrowser/#/R-MMU-844438 NLRP1 oligomerizes IEA Mus musculus 59414 R-MMU-844447 https://reactome.org/PathwayBrowser/#/R-MMU-844447 NLRP1 senses MDP IEA Mus musculus 59414 R-MMU-879222 https://reactome.org/PathwayBrowser/#/R-MMU-879222 MDP:NLRP1 binds ATP IEA Mus musculus 59414 R-RNO-168405 https://reactome.org/PathwayBrowser/#/R-RNO-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Rattus norvegicus 59414 R-RNO-168412 https://reactome.org/PathwayBrowser/#/R-RNO-168412 MDP elicits a NOD2 response IEA Rattus norvegicus 59414 R-RNO-450337 https://reactome.org/PathwayBrowser/#/R-RNO-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Rattus norvegicus 59414 R-RNO-450346 https://reactome.org/PathwayBrowser/#/R-RNO-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Rattus norvegicus 59414 R-RNO-622415 https://reactome.org/PathwayBrowser/#/R-RNO-622415 RIP2 binds NEMO IEA Rattus norvegicus 59414 R-RNO-688136 https://reactome.org/PathwayBrowser/#/R-RNO-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Rattus norvegicus 59414 R-RNO-688137 https://reactome.org/PathwayBrowser/#/R-RNO-688137 RIP2 is K63 polyubiquitinated IEA Rattus norvegicus 59414 R-RNO-688985 https://reactome.org/PathwayBrowser/#/R-RNO-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Rattus norvegicus 59414 R-RNO-706479 https://reactome.org/PathwayBrowser/#/R-RNO-706479 TAK1 is activated IEA Rattus norvegicus 59414 R-RNO-708349 https://reactome.org/PathwayBrowser/#/R-RNO-708349 Activated NOD2 oligomerizes IEA Rattus norvegicus 59414 R-RNO-741411 https://reactome.org/PathwayBrowser/#/R-RNO-741411 CYLD deubiquitinates NEMO IEA Rattus norvegicus 59414 R-RNO-844438 https://reactome.org/PathwayBrowser/#/R-RNO-844438 NLRP1 oligomerizes IEA Rattus norvegicus 59414 R-RNO-844447 https://reactome.org/PathwayBrowser/#/R-RNO-844447 NLRP1 senses MDP IEA Rattus norvegicus 59414 R-RNO-879222 https://reactome.org/PathwayBrowser/#/R-RNO-879222 MDP:NLRP1 binds ATP IEA Rattus norvegicus 59440 R-BTA-9603982 https://reactome.org/PathwayBrowser/#/R-BTA-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Bos taurus 59440 R-CEL-9603982 https://reactome.org/PathwayBrowser/#/R-CEL-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Caenorhabditis elegans 59440 R-CFA-9603982 https://reactome.org/PathwayBrowser/#/R-CFA-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Canis familiaris 59440 R-HSA-9603982 https://reactome.org/PathwayBrowser/#/R-HSA-9603982 FUT2 transfers Fuc to LeA to form LeB TAS Homo sapiens 59440 R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 59440 R-MMU-9603982 https://reactome.org/PathwayBrowser/#/R-MMU-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Mus musculus 59440 R-RNO-9603982 https://reactome.org/PathwayBrowser/#/R-RNO-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Rattus norvegicus 59440 R-SSC-9603982 https://reactome.org/PathwayBrowser/#/R-SSC-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Sus scrofa 59440 R-XTR-9603982 https://reactome.org/PathwayBrowser/#/R-XTR-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Xenopus tropicalis 59458 R-BTA-196753 https://reactome.org/PathwayBrowser/#/R-BTA-196753 2xPPCS ligates PPanK with Cys IEA Bos taurus 59458 R-BTA-196840 https://reactome.org/PathwayBrowser/#/R-BTA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Bos taurus 59458 R-CEL-196753 https://reactome.org/PathwayBrowser/#/R-CEL-196753 2xPPCS ligates PPanK with Cys IEA Caenorhabditis elegans 59458 R-CEL-196840 https://reactome.org/PathwayBrowser/#/R-CEL-196840 3xPPCDC:3FMN decarboxylates PPC IEA Caenorhabditis elegans 59458 R-CFA-196753 https://reactome.org/PathwayBrowser/#/R-CFA-196753 2xPPCS ligates PPanK with Cys IEA Canis familiaris 59458 R-CFA-196840 https://reactome.org/PathwayBrowser/#/R-CFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Canis familiaris 59458 R-DDI-196753 https://reactome.org/PathwayBrowser/#/R-DDI-196753 2xPPCS ligates PPanK with Cys IEA Dictyostelium discoideum 59458 R-DDI-196840 https://reactome.org/PathwayBrowser/#/R-DDI-196840 3xPPCDC:3FMN decarboxylates PPC IEA Dictyostelium discoideum 59458 R-DME-196753 https://reactome.org/PathwayBrowser/#/R-DME-196753 2xPPCS ligates PPanK with Cys IEA Drosophila melanogaster 59458 R-DME-196840 https://reactome.org/PathwayBrowser/#/R-DME-196840 3xPPCDC:3FMN decarboxylates PPC IEA Drosophila melanogaster 59458 R-DRE-196753 https://reactome.org/PathwayBrowser/#/R-DRE-196753 2xPPCS ligates PPanK with Cys IEA Danio rerio 59458 R-GGA-196753 https://reactome.org/PathwayBrowser/#/R-GGA-196753 2xPPCS ligates PPanK with Cys IEA Gallus gallus 59458 R-GGA-196840 https://reactome.org/PathwayBrowser/#/R-GGA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Gallus gallus 59458 R-HSA-196753 https://reactome.org/PathwayBrowser/#/R-HSA-196753 2xPPCS ligates PPanK with Cys TAS Homo sapiens 59458 R-HSA-196840 https://reactome.org/PathwayBrowser/#/R-HSA-196840 3xPPCDC:3FMN decarboxylates PPC TAS Homo sapiens 59458 R-MMU-196753 https://reactome.org/PathwayBrowser/#/R-MMU-196753 2xPPCS ligates PPanK with Cys IEA Mus musculus 59458 R-MMU-196840 https://reactome.org/PathwayBrowser/#/R-MMU-196840 3xPPCDC:3FMN decarboxylates PPC IEA Mus musculus 59458 R-PFA-196753 https://reactome.org/PathwayBrowser/#/R-PFA-196753 2xPPCS ligates PPanK with Cys IEA Plasmodium falciparum 59458 R-PFA-196840 https://reactome.org/PathwayBrowser/#/R-PFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Plasmodium falciparum 59458 R-RNO-196753 https://reactome.org/PathwayBrowser/#/R-RNO-196753 2xPPCS ligates PPanK with Cys IEA Rattus norvegicus 59458 R-RNO-196840 https://reactome.org/PathwayBrowser/#/R-RNO-196840 3xPPCDC:3FMN decarboxylates PPC IEA Rattus norvegicus 59458 R-SCE-196753 https://reactome.org/PathwayBrowser/#/R-SCE-196753 2xPPCS ligates PPanK with Cys IEA Saccharomyces cerevisiae 59458 R-SCE-196840 https://reactome.org/PathwayBrowser/#/R-SCE-196840 3xPPCDC:3FMN decarboxylates PPC IEA Saccharomyces cerevisiae 59458 R-SPO-196753 https://reactome.org/PathwayBrowser/#/R-SPO-196753 2xPPCS ligates PPanK with Cys IEA Schizosaccharomyces pombe 59458 R-SSC-196753 https://reactome.org/PathwayBrowser/#/R-SSC-196753 2xPPCS ligates PPanK with Cys IEA Sus scrofa 59458 R-SSC-196840 https://reactome.org/PathwayBrowser/#/R-SSC-196840 3xPPCDC:3FMN decarboxylates PPC IEA Sus scrofa 59458 R-XTR-196753 https://reactome.org/PathwayBrowser/#/R-XTR-196753 2xPPCS ligates PPanK with Cys IEA Xenopus tropicalis 59458 R-XTR-196840 https://reactome.org/PathwayBrowser/#/R-XTR-196840 3xPPCDC:3FMN decarboxylates PPC IEA Xenopus tropicalis 59496 R-BTA-6804527 https://reactome.org/PathwayBrowser/#/R-BTA-6804527 INTL1 binds bacterial glycans IEA Bos taurus 59496 R-DRE-6804527 https://reactome.org/PathwayBrowser/#/R-DRE-6804527 INTL1 binds bacterial glycans IEA Danio rerio 59496 R-HSA-6804527 https://reactome.org/PathwayBrowser/#/R-HSA-6804527 INTL1 binds bacterial glycans TAS Homo sapiens 59496 R-MMU-6804527 https://reactome.org/PathwayBrowser/#/R-MMU-6804527 INTL1 binds bacterial glycans IEA Mus musculus 59496 R-RNO-6804527 https://reactome.org/PathwayBrowser/#/R-RNO-6804527 INTL1 binds bacterial glycans IEA Rattus norvegicus 59496 R-SSC-6804527 https://reactome.org/PathwayBrowser/#/R-SSC-6804527 INTL1 binds bacterial glycans IEA Sus scrofa 59496 R-XTR-6804527 https://reactome.org/PathwayBrowser/#/R-XTR-6804527 INTL1 binds bacterial glycans IEA Xenopus tropicalis 59513 R-BTA-198845 https://reactome.org/PathwayBrowser/#/R-BTA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Bos taurus 59513 R-CEL-198845 https://reactome.org/PathwayBrowser/#/R-CEL-198845 CYB5A:heme reduces Asc.- to AscH- IEA Caenorhabditis elegans 59513 R-CFA-198845 https://reactome.org/PathwayBrowser/#/R-CFA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Canis familiaris 59513 R-DDI-198845 https://reactome.org/PathwayBrowser/#/R-DDI-198845 CYB5A:heme reduces Asc.- to AscH- IEA Dictyostelium discoideum 59513 R-DME-198845 https://reactome.org/PathwayBrowser/#/R-DME-198845 CYB5A:heme reduces Asc.- to AscH- IEA Drosophila melanogaster 59513 R-DRE-198845 https://reactome.org/PathwayBrowser/#/R-DRE-198845 CYB5A:heme reduces Asc.- to AscH- IEA Danio rerio 59513 R-GGA-198845 https://reactome.org/PathwayBrowser/#/R-GGA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Gallus gallus 59513 R-HSA-1497855 https://reactome.org/PathwayBrowser/#/R-HSA-1497855 Ascorbate can reduce the BH3 radical back to BH4 TAS Homo sapiens 59513 R-HSA-198845 https://reactome.org/PathwayBrowser/#/R-HSA-198845 CYB5A:heme reduces Asc.- to AscH- TAS Homo sapiens 59513 R-HSA-9640302 https://reactome.org/PathwayBrowser/#/R-HSA-9640302 Asc.- radical dissociates to AscH- and DeHA TAS Homo sapiens 59513 R-MMU-198845 https://reactome.org/PathwayBrowser/#/R-MMU-198845 CYB5A:heme reduces Asc.- to AscH- IEA Mus musculus 59513 R-RNO-198845 https://reactome.org/PathwayBrowser/#/R-RNO-198845 CYB5A:heme reduces Asc.- to AscH- IEA Rattus norvegicus 59513 R-SCE-198845 https://reactome.org/PathwayBrowser/#/R-SCE-198845 CYB5A:heme reduces Asc.- to AscH- IEA Saccharomyces cerevisiae 59513 R-SPO-198845 https://reactome.org/PathwayBrowser/#/R-SPO-198845 CYB5A:heme reduces Asc.- to AscH- IEA Schizosaccharomyces pombe 59513 R-SSC-198845 https://reactome.org/PathwayBrowser/#/R-SSC-198845 CYB5A:heme reduces Asc.- to AscH- IEA Sus scrofa 59513 R-XTR-198845 https://reactome.org/PathwayBrowser/#/R-XTR-198845 CYB5A:heme reduces Asc.- to AscH- IEA Xenopus tropicalis 59520 R-BTA-1022129 https://reactome.org/PathwayBrowser/#/R-BTA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Bos taurus 59520 R-BTA-1022133 https://reactome.org/PathwayBrowser/#/R-BTA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Bos taurus 59520 R-BTA-1028788 https://reactome.org/PathwayBrowser/#/R-BTA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Bos taurus 59520 R-BTA-5693807 https://reactome.org/PathwayBrowser/#/R-BTA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Bos taurus 59520 R-BTA-975902 https://reactome.org/PathwayBrowser/#/R-BTA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Bos taurus 59520 R-BTA-975903 https://reactome.org/PathwayBrowser/#/R-BTA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Bos taurus 59520 R-BTA-975916 https://reactome.org/PathwayBrowser/#/R-BTA-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Bos taurus 59520 R-BTA-975919 https://reactome.org/PathwayBrowser/#/R-BTA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Bos taurus 59520 R-BTA-975926 https://reactome.org/PathwayBrowser/#/R-BTA-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Bos taurus 59520 R-CEL-1028788 https://reactome.org/PathwayBrowser/#/R-CEL-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Caenorhabditis elegans 59520 R-CEL-5693807 https://reactome.org/PathwayBrowser/#/R-CEL-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Caenorhabditis elegans 59520 R-CEL-975916 https://reactome.org/PathwayBrowser/#/R-CEL-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Caenorhabditis elegans 59520 R-CFA-1022129 https://reactome.org/PathwayBrowser/#/R-CFA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Canis familiaris 59520 R-CFA-1022133 https://reactome.org/PathwayBrowser/#/R-CFA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Canis familiaris 59520 R-CFA-1028788 https://reactome.org/PathwayBrowser/#/R-CFA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Canis familiaris 59520 R-CFA-5693807 https://reactome.org/PathwayBrowser/#/R-CFA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Canis familiaris 59520 R-CFA-975902 https://reactome.org/PathwayBrowser/#/R-CFA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Canis familiaris 59520 R-CFA-975903 https://reactome.org/PathwayBrowser/#/R-CFA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Canis familiaris 59520 R-CFA-975916 https://reactome.org/PathwayBrowser/#/R-CFA-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Canis familiaris 59520 R-CFA-975919 https://reactome.org/PathwayBrowser/#/R-CFA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Canis familiaris 59520 R-DDI-5693807 https://reactome.org/PathwayBrowser/#/R-DDI-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Dictyostelium discoideum 59520 R-DDI-975926 https://reactome.org/PathwayBrowser/#/R-DDI-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Dictyostelium discoideum 59520 R-DME-1028788 https://reactome.org/PathwayBrowser/#/R-DME-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Drosophila melanogaster 59520 R-DME-5693807 https://reactome.org/PathwayBrowser/#/R-DME-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Drosophila melanogaster 59520 R-DME-975902 https://reactome.org/PathwayBrowser/#/R-DME-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Drosophila melanogaster 59520 R-DME-975903 https://reactome.org/PathwayBrowser/#/R-DME-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Drosophila melanogaster 59520 R-DME-975919 https://reactome.org/PathwayBrowser/#/R-DME-975919 Addition of galactose by beta 4-galactosyltransferases IEA Drosophila melanogaster 59520 R-DME-975926 https://reactome.org/PathwayBrowser/#/R-DME-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Drosophila melanogaster 59520 R-DRE-1022129 https://reactome.org/PathwayBrowser/#/R-DRE-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Danio rerio 59520 R-DRE-1022133 https://reactome.org/PathwayBrowser/#/R-DRE-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Danio rerio 59520 R-DRE-1028788 https://reactome.org/PathwayBrowser/#/R-DRE-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Danio rerio 59520 R-DRE-5693807 https://reactome.org/PathwayBrowser/#/R-DRE-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Danio rerio 59520 R-DRE-975903 https://reactome.org/PathwayBrowser/#/R-DRE-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Danio rerio 59520 R-DRE-975916 https://reactome.org/PathwayBrowser/#/R-DRE-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Danio rerio 59520 R-DRE-975919 https://reactome.org/PathwayBrowser/#/R-DRE-975919 Addition of galactose by beta 4-galactosyltransferases IEA Danio rerio 59520 R-GGA-1022129 https://reactome.org/PathwayBrowser/#/R-GGA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Gallus gallus 59520 R-GGA-1022133 https://reactome.org/PathwayBrowser/#/R-GGA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Gallus gallus 59520 R-GGA-1028788 https://reactome.org/PathwayBrowser/#/R-GGA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Gallus gallus 59520 R-GGA-5693807 https://reactome.org/PathwayBrowser/#/R-GGA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Gallus gallus 59520 R-GGA-975902 https://reactome.org/PathwayBrowser/#/R-GGA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Gallus gallus 59520 R-GGA-975903 https://reactome.org/PathwayBrowser/#/R-GGA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Gallus gallus 59520 R-GGA-975916 https://reactome.org/PathwayBrowser/#/R-GGA-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Gallus gallus 59520 R-GGA-975919 https://reactome.org/PathwayBrowser/#/R-GGA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Gallus gallus 59520 R-GGA-975926 https://reactome.org/PathwayBrowser/#/R-GGA-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Gallus gallus 59520 R-HSA-1022129 https://reactome.org/PathwayBrowser/#/R-HSA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans TAS Homo sapiens 59520 R-HSA-1022133 https://reactome.org/PathwayBrowser/#/R-HSA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans TAS Homo sapiens 59520 R-HSA-1028788 https://reactome.org/PathwayBrowser/#/R-HSA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP TAS Homo sapiens 59520 R-HSA-4793956 https://reactome.org/PathwayBrowser/#/R-HSA-4793956 Defective B4GALT1 does not add Gal to N-glycan TAS Homo sapiens 59520 R-HSA-5693807 https://reactome.org/PathwayBrowser/#/R-HSA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc TAS Homo sapiens 59520 R-HSA-9683488 https://reactome.org/PathwayBrowser/#/R-HSA-9683488 ACE2 is glycosylated to glycosylated-ACE2 TAS Homo sapiens 59520 R-HSA-975902 https://reactome.org/PathwayBrowser/#/R-HSA-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans TAS Homo sapiens 59520 R-HSA-975903 https://reactome.org/PathwayBrowser/#/R-HSA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV TAS Homo sapiens 59520 R-HSA-975916 https://reactome.org/PathwayBrowser/#/R-HSA-975916 Addition of GlcNAc to position 5 by MGAT5 TAS Homo sapiens 59520 R-HSA-975919 https://reactome.org/PathwayBrowser/#/R-HSA-975919 Addition of galactose by beta 4-galactosyltransferases TAS Homo sapiens 59520 R-HSA-975926 https://reactome.org/PathwayBrowser/#/R-HSA-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 TAS Homo sapiens 59520 R-MMU-1022129 https://reactome.org/PathwayBrowser/#/R-MMU-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Mus musculus 59520 R-MMU-1022133 https://reactome.org/PathwayBrowser/#/R-MMU-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Mus musculus 59520 R-MMU-1028788 https://reactome.org/PathwayBrowser/#/R-MMU-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Mus musculus 59520 R-MMU-5693807 https://reactome.org/PathwayBrowser/#/R-MMU-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Mus musculus 59520 R-MMU-975902 https://reactome.org/PathwayBrowser/#/R-MMU-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Mus musculus 59520 R-MMU-975903 https://reactome.org/PathwayBrowser/#/R-MMU-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Mus musculus 59520 R-MMU-975916 https://reactome.org/PathwayBrowser/#/R-MMU-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Mus musculus 59520 R-MMU-975919 https://reactome.org/PathwayBrowser/#/R-MMU-975919 Addition of galactose by beta 4-galactosyltransferases IEA Mus musculus 59520 R-MMU-975926 https://reactome.org/PathwayBrowser/#/R-MMU-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Mus musculus 59520 R-RNO-1022129 https://reactome.org/PathwayBrowser/#/R-RNO-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Rattus norvegicus 59520 R-RNO-1022133 https://reactome.org/PathwayBrowser/#/R-RNO-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Rattus norvegicus 59520 R-RNO-1028788 https://reactome.org/PathwayBrowser/#/R-RNO-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Rattus norvegicus 59520 R-RNO-5693807 https://reactome.org/PathwayBrowser/#/R-RNO-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Rattus norvegicus 59520 R-RNO-975902 https://reactome.org/PathwayBrowser/#/R-RNO-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Rattus norvegicus 59520 R-RNO-975903 https://reactome.org/PathwayBrowser/#/R-RNO-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Rattus norvegicus 59520 R-RNO-975916 https://reactome.org/PathwayBrowser/#/R-RNO-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Rattus norvegicus 59520 R-RNO-975919 https://reactome.org/PathwayBrowser/#/R-RNO-975919 Addition of galactose by beta 4-galactosyltransferases IEA Rattus norvegicus 59520 R-RNO-975926 https://reactome.org/PathwayBrowser/#/R-RNO-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Rattus norvegicus 59520 R-SSC-1022129 https://reactome.org/PathwayBrowser/#/R-SSC-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Sus scrofa 59520 R-SSC-1022133 https://reactome.org/PathwayBrowser/#/R-SSC-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Sus scrofa 59520 R-SSC-1028788 https://reactome.org/PathwayBrowser/#/R-SSC-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Sus scrofa 59520 R-SSC-5693807 https://reactome.org/PathwayBrowser/#/R-SSC-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Sus scrofa 59520 R-SSC-975902 https://reactome.org/PathwayBrowser/#/R-SSC-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Sus scrofa 59520 R-SSC-975903 https://reactome.org/PathwayBrowser/#/R-SSC-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Sus scrofa 59520 R-SSC-975916 https://reactome.org/PathwayBrowser/#/R-SSC-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Sus scrofa 59520 R-SSC-975919 https://reactome.org/PathwayBrowser/#/R-SSC-975919 Addition of galactose by beta 4-galactosyltransferases IEA Sus scrofa 59520 R-SSC-975926 https://reactome.org/PathwayBrowser/#/R-SSC-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Sus scrofa 59520 R-XTR-1022129 https://reactome.org/PathwayBrowser/#/R-XTR-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Xenopus tropicalis 59520 R-XTR-1022133 https://reactome.org/PathwayBrowser/#/R-XTR-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Xenopus tropicalis 59520 R-XTR-1028788 https://reactome.org/PathwayBrowser/#/R-XTR-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Xenopus tropicalis 59520 R-XTR-5693807 https://reactome.org/PathwayBrowser/#/R-XTR-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Xenopus tropicalis 59520 R-XTR-975902 https://reactome.org/PathwayBrowser/#/R-XTR-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Xenopus tropicalis 59520 R-XTR-975903 https://reactome.org/PathwayBrowser/#/R-XTR-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Xenopus tropicalis 59520 R-XTR-975916 https://reactome.org/PathwayBrowser/#/R-XTR-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Xenopus tropicalis 59520 R-XTR-975919 https://reactome.org/PathwayBrowser/#/R-XTR-975919 Addition of galactose by beta 4-galactosyltransferases IEA Xenopus tropicalis 59520 R-XTR-975926 https://reactome.org/PathwayBrowser/#/R-XTR-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Xenopus tropicalis 59524 R-BTA-8850356 https://reactome.org/PathwayBrowser/#/R-BTA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Bos taurus 59524 R-GGA-8850356 https://reactome.org/PathwayBrowser/#/R-GGA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Gallus gallus 59524 R-HSA-5621573 https://reactome.org/PathwayBrowser/#/R-HSA-5621573 CD209 activate GTPase RAS TAS Homo sapiens 59524 R-HSA-5621606 https://reactome.org/PathwayBrowser/#/R-HSA-5621606 CD209 binds ManLAM TAS Homo sapiens 59524 R-HSA-8850356 https://reactome.org/PathwayBrowser/#/R-HSA-8850356 TCR binds microbial lipid-based antigen via CD1 TAS Homo sapiens 59524 R-HSA-9636404 https://reactome.org/PathwayBrowser/#/R-HSA-9636404 LAM translocates from the cell wall to the plasma membrane TAS Homo sapiens 59524 R-HSA-9697064 https://reactome.org/PathwayBrowser/#/R-HSA-9697064 lprG binds to LAM,LM TAS Homo sapiens 59524 R-HSA-9697070 https://reactome.org/PathwayBrowser/#/R-HSA-9697070 lprG dissociates from LAM,LM TAS Homo sapiens 59524 R-HSA-9697077 https://reactome.org/PathwayBrowser/#/R-HSA-9697077 Rv1410c transports lprG:LM,LAM from cytosol to the cell wall TAS Homo sapiens 59524 R-SSC-8850356 https://reactome.org/PathwayBrowser/#/R-SSC-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Sus scrofa 59554 R-BTA-5690042 https://reactome.org/PathwayBrowser/#/R-BTA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 59554 R-BTA-5690043 https://reactome.org/PathwayBrowser/#/R-BTA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 59554 R-BTA-5690066 https://reactome.org/PathwayBrowser/#/R-BTA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 59554 R-BTA-5696004 https://reactome.org/PathwayBrowser/#/R-BTA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Bos taurus 59554 R-CEL-5690042 https://reactome.org/PathwayBrowser/#/R-CEL-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 59554 R-CEL-5690043 https://reactome.org/PathwayBrowser/#/R-CEL-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 59554 R-CEL-5690066 https://reactome.org/PathwayBrowser/#/R-CEL-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 59554 R-CEL-5696004 https://reactome.org/PathwayBrowser/#/R-CEL-5696004 ACSF2 ligates CoA-SH to MCFA IEA Caenorhabditis elegans 59554 R-CFA-5690042 https://reactome.org/PathwayBrowser/#/R-CFA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 59554 R-CFA-5690043 https://reactome.org/PathwayBrowser/#/R-CFA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 59554 R-CFA-5690066 https://reactome.org/PathwayBrowser/#/R-CFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 59554 R-CFA-5696004 https://reactome.org/PathwayBrowser/#/R-CFA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Canis familiaris 59554 R-DDI-5690043 https://reactome.org/PathwayBrowser/#/R-DDI-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 59554 R-DDI-5690066 https://reactome.org/PathwayBrowser/#/R-DDI-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 59554 R-DME-5690043 https://reactome.org/PathwayBrowser/#/R-DME-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 59554 R-DME-5690066 https://reactome.org/PathwayBrowser/#/R-DME-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 59554 R-DME-5696004 https://reactome.org/PathwayBrowser/#/R-DME-5696004 ACSF2 ligates CoA-SH to MCFA IEA Drosophila melanogaster 59554 R-DRE-5690042 https://reactome.org/PathwayBrowser/#/R-DRE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 59554 R-DRE-5690066 https://reactome.org/PathwayBrowser/#/R-DRE-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 59554 R-DRE-5696004 https://reactome.org/PathwayBrowser/#/R-DRE-5696004 ACSF2 ligates CoA-SH to MCFA IEA Danio rerio 59554 R-GGA-5690042 https://reactome.org/PathwayBrowser/#/R-GGA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 59554 R-GGA-5690043 https://reactome.org/PathwayBrowser/#/R-GGA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 59554 R-GGA-5690066 https://reactome.org/PathwayBrowser/#/R-GGA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 59554 R-GGA-5696004 https://reactome.org/PathwayBrowser/#/R-GGA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Gallus gallus 59554 R-HSA-5690042 https://reactome.org/PathwayBrowser/#/R-HSA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 59554 R-HSA-5690043 https://reactome.org/PathwayBrowser/#/R-HSA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 59554 R-HSA-5690066 https://reactome.org/PathwayBrowser/#/R-HSA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 59554 R-HSA-5696004 https://reactome.org/PathwayBrowser/#/R-HSA-5696004 ACSF2 ligates CoA-SH to MCFA TAS Homo sapiens 59554 R-MMU-5690042 https://reactome.org/PathwayBrowser/#/R-MMU-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 59554 R-MMU-5690043 https://reactome.org/PathwayBrowser/#/R-MMU-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 59554 R-MMU-5690066 https://reactome.org/PathwayBrowser/#/R-MMU-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 59554 R-MMU-5696004 https://reactome.org/PathwayBrowser/#/R-MMU-5696004 ACSF2 ligates CoA-SH to MCFA IEA Mus musculus 59554 R-PFA-5690066 https://reactome.org/PathwayBrowser/#/R-PFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Plasmodium falciparum 59554 R-RNO-5690042 https://reactome.org/PathwayBrowser/#/R-RNO-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 59554 R-RNO-5690043 https://reactome.org/PathwayBrowser/#/R-RNO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 59554 R-RNO-5690066 https://reactome.org/PathwayBrowser/#/R-RNO-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 59554 R-RNO-5696004 https://reactome.org/PathwayBrowser/#/R-RNO-5696004 ACSF2 ligates CoA-SH to MCFA IEA Rattus norvegicus 59554 R-SCE-5690042 https://reactome.org/PathwayBrowser/#/R-SCE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Saccharomyces cerevisiae 59554 R-SPO-5690043 https://reactome.org/PathwayBrowser/#/R-SPO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Schizosaccharomyces pombe 59554 R-SSC-5690042 https://reactome.org/PathwayBrowser/#/R-SSC-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 59554 R-SSC-5690043 https://reactome.org/PathwayBrowser/#/R-SSC-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 59554 R-SSC-5690066 https://reactome.org/PathwayBrowser/#/R-SSC-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 59554 R-SSC-5696004 https://reactome.org/PathwayBrowser/#/R-SSC-5696004 ACSF2 ligates CoA-SH to MCFA IEA Sus scrofa 59554 R-XTR-5690042 https://reactome.org/PathwayBrowser/#/R-XTR-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 59554 R-XTR-5690043 https://reactome.org/PathwayBrowser/#/R-XTR-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 59554 R-XTR-5690066 https://reactome.org/PathwayBrowser/#/R-XTR-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 59554 R-XTR-5696004 https://reactome.org/PathwayBrowser/#/R-XTR-5696004 ACSF2 ligates CoA-SH to MCFA IEA Xenopus tropicalis 5959 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(34-41) binds to AGTR1 IEA Bos taurus 5959 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGRT1 IEA Bos taurus 5959 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(34-41) binds to AGTR1 IEA Caenorhabditis elegans 5959 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGRT1 IEA Caenorhabditis elegans 5959 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(34-41) binds to AGTR1 IEA Canis familiaris 5959 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGRT1 IEA Canis familiaris 5959 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(34-41) binds to AGTR1 IEA Drosophila melanogaster 5959 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGRT1 IEA Drosophila melanogaster 5959 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(34-41) binds to AGTR1 IEA Danio rerio 5959 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGRT1 IEA Danio rerio 5959 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(34-41) binds to AGTR1 IEA Gallus gallus 5959 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGRT1 IEA Gallus gallus 5959 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(34-41) binds to AGTR1 TAS Homo sapiens 5959 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGRT1 TAS Homo sapiens 5959 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(34-41) binds to AGTR1 IEA Mus musculus 5959 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGRT1 IEA Mus musculus 5959 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(34-41) binds to AGTR1 IEA Rattus norvegicus 5959 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGRT1 IEA Rattus norvegicus 5959 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(34-41) binds to AGTR1 IEA Sus scrofa 5959 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGRT1 IEA Sus scrofa 59629 R-MTU-879273 https://reactome.org/PathwayBrowser/#/R-MTU-879273 mycothiol conjugates with electrophilic xenobiotic TAS Mycobacterium tuberculosis 59629 R-MTU-879311 https://reactome.org/PathwayBrowser/#/R-MTU-879311 mycothiol S-conjugate is cleaved into mercapturic acid and GlcN-Ins TAS Mycobacterium tuberculosis 59630 R-MTU-879273 https://reactome.org/PathwayBrowser/#/R-MTU-879273 mycothiol conjugates with electrophilic xenobiotic TAS Mycobacterium tuberculosis 59630 R-MTU-879311 https://reactome.org/PathwayBrowser/#/R-MTU-879311 mycothiol S-conjugate is cleaved into mercapturic acid and GlcN-Ins TAS Mycobacterium tuberculosis 59632 R-MTU-879311 https://reactome.org/PathwayBrowser/#/R-MTU-879311 mycothiol S-conjugate is cleaved into mercapturic acid and GlcN-Ins TAS Mycobacterium tuberculosis 59634 R-MTU-879311 https://reactome.org/PathwayBrowser/#/R-MTU-879311 mycothiol S-conjugate is cleaved into mercapturic acid and GlcN-Ins TAS Mycobacterium tuberculosis 59637 R-HSA-1222583 https://reactome.org/PathwayBrowser/#/R-HSA-1222583 MscR reduces nitrosomycothiol to ammonia TAS Homo sapiens 59637 R-HSA-1222594 https://reactome.org/PathwayBrowser/#/R-HSA-1222594 Mycothiol scavenges nitrosyl TAS Homo sapiens 59640 R-BTA-6799977 https://reactome.org/PathwayBrowser/#/R-BTA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Bos taurus 59640 R-CFA-6799977 https://reactome.org/PathwayBrowser/#/R-CFA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Canis familiaris 59640 R-DME-6799977 https://reactome.org/PathwayBrowser/#/R-DME-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Drosophila melanogaster 59640 R-DRE-6799977 https://reactome.org/PathwayBrowser/#/R-DRE-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Danio rerio 59640 R-GGA-6799977 https://reactome.org/PathwayBrowser/#/R-GGA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Gallus gallus 59640 R-HSA-6799977 https://reactome.org/PathwayBrowser/#/R-HSA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan TAS Homo sapiens 59640 R-MMU-6799977 https://reactome.org/PathwayBrowser/#/R-MMU-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Mus musculus 59640 R-RNO-6799977 https://reactome.org/PathwayBrowser/#/R-RNO-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Rattus norvegicus 59640 R-SSC-6799977 https://reactome.org/PathwayBrowser/#/R-SSC-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Sus scrofa 59640 R-XTR-6799977 https://reactome.org/PathwayBrowser/#/R-XTR-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Xenopus tropicalis 59648 R-BTA-947535 https://reactome.org/PathwayBrowser/#/R-BTA-947535 Cyclisation of GTP to precursor Z IEA Bos taurus 59648 R-CEL-947535 https://reactome.org/PathwayBrowser/#/R-CEL-947535 Cyclisation of GTP to precursor Z IEA Caenorhabditis elegans 59648 R-CFA-947535 https://reactome.org/PathwayBrowser/#/R-CFA-947535 Cyclisation of GTP to precursor Z IEA Canis familiaris 59648 R-DDI-947535 https://reactome.org/PathwayBrowser/#/R-DDI-947535 Cyclisation of GTP to precursor Z IEA Dictyostelium discoideum 59648 R-DME-947535 https://reactome.org/PathwayBrowser/#/R-DME-947535 Cyclisation of GTP to precursor Z IEA Drosophila melanogaster 59648 R-GGA-947535 https://reactome.org/PathwayBrowser/#/R-GGA-947535 Cyclisation of GTP to precursor Z IEA Gallus gallus 59648 R-HSA-947535 https://reactome.org/PathwayBrowser/#/R-HSA-947535 Cyclisation of GTP to precursor Z TAS Homo sapiens 59648 R-HSA-947541 https://reactome.org/PathwayBrowser/#/R-HSA-947541 Sulfhydrylation and ring cleavage of precursor Z TAS Homo sapiens 59648 R-MMU-947535 https://reactome.org/PathwayBrowser/#/R-MMU-947535 Cyclisation of GTP to precursor Z IEA Mus musculus 59648 R-RNO-947535 https://reactome.org/PathwayBrowser/#/R-RNO-947535 Cyclisation of GTP to precursor Z IEA Rattus norvegicus 59648 R-SSC-947535 https://reactome.org/PathwayBrowser/#/R-SSC-947535 Cyclisation of GTP to precursor Z IEA Sus scrofa 59648 R-XTR-947535 https://reactome.org/PathwayBrowser/#/R-XTR-947535 Cyclisation of GTP to precursor Z IEA Xenopus tropicalis 59696 R-BTA-1606839 https://reactome.org/PathwayBrowser/#/R-BTA-1606839 ARSC hydrolyzes steroid sulfates IEA Bos taurus 59696 R-CFA-1606839 https://reactome.org/PathwayBrowser/#/R-CFA-1606839 ARSC hydrolyzes steroid sulfates IEA Canis familiaris 59696 R-GGA-1606839 https://reactome.org/PathwayBrowser/#/R-GGA-1606839 ARSC hydrolyzes steroid sulfates IEA Gallus gallus 59696 R-HSA-1606839 https://reactome.org/PathwayBrowser/#/R-HSA-1606839 ARSC hydrolyzes steroid sulfates TAS Homo sapiens 59696 R-MMU-1606839 https://reactome.org/PathwayBrowser/#/R-MMU-1606839 ARSC hydrolyzes steroid sulfates IEA Mus musculus 59696 R-RNO-1606839 https://reactome.org/PathwayBrowser/#/R-RNO-1606839 ARSC hydrolyzes steroid sulfates IEA Rattus norvegicus 59696 R-SPO-1606839 https://reactome.org/PathwayBrowser/#/R-SPO-1606839 ARSC hydrolyzes steroid sulfates IEA Schizosaccharomyces pombe 59696 R-SSC-1606839 https://reactome.org/PathwayBrowser/#/R-SSC-1606839 ARSC hydrolyzes steroid sulfates IEA Sus scrofa 59696 R-XTR-1606839 https://reactome.org/PathwayBrowser/#/R-XTR-1606839 ARSC hydrolyzes steroid sulfates IEA Xenopus tropicalis 597326 R-BTA-964970 https://reactome.org/PathwayBrowser/#/R-BTA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Bos taurus 597326 R-BTA-965019 https://reactome.org/PathwayBrowser/#/R-BTA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Bos taurus 597326 R-BTA-965079 https://reactome.org/PathwayBrowser/#/R-BTA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Bos taurus 597326 R-CEL-964970 https://reactome.org/PathwayBrowser/#/R-CEL-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Caenorhabditis elegans 597326 R-CEL-965019 https://reactome.org/PathwayBrowser/#/R-CEL-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Caenorhabditis elegans 597326 R-CEL-965079 https://reactome.org/PathwayBrowser/#/R-CEL-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Caenorhabditis elegans 597326 R-CFA-964970 https://reactome.org/PathwayBrowser/#/R-CFA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Canis familiaris 597326 R-CFA-965019 https://reactome.org/PathwayBrowser/#/R-CFA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Canis familiaris 597326 R-CFA-965079 https://reactome.org/PathwayBrowser/#/R-CFA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Canis familiaris 597326 R-DDI-964970 https://reactome.org/PathwayBrowser/#/R-DDI-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Dictyostelium discoideum 597326 R-DDI-965019 https://reactome.org/PathwayBrowser/#/R-DDI-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Dictyostelium discoideum 597326 R-DDI-965079 https://reactome.org/PathwayBrowser/#/R-DDI-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Dictyostelium discoideum 597326 R-DME-964970 https://reactome.org/PathwayBrowser/#/R-DME-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Drosophila melanogaster 597326 R-DME-965019 https://reactome.org/PathwayBrowser/#/R-DME-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Drosophila melanogaster 597326 R-DME-965079 https://reactome.org/PathwayBrowser/#/R-DME-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Drosophila melanogaster 597326 R-DRE-964970 https://reactome.org/PathwayBrowser/#/R-DRE-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Danio rerio 597326 R-GGA-964970 https://reactome.org/PathwayBrowser/#/R-GGA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Gallus gallus 597326 R-GGA-965019 https://reactome.org/PathwayBrowser/#/R-GGA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Gallus gallus 597326 R-GGA-965079 https://reactome.org/PathwayBrowser/#/R-GGA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Gallus gallus 597326 R-HSA-964970 https://reactome.org/PathwayBrowser/#/R-HSA-964970 2xPDXK:2xZn2+ phosphorylates PXL TAS Homo sapiens 597326 R-HSA-965019 https://reactome.org/PathwayBrowser/#/R-HSA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP TAS Homo sapiens 597326 R-HSA-965079 https://reactome.org/PathwayBrowser/#/R-HSA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP TAS Homo sapiens 597326 R-MMU-964970 https://reactome.org/PathwayBrowser/#/R-MMU-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Mus musculus 597326 R-MMU-965019 https://reactome.org/PathwayBrowser/#/R-MMU-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Mus musculus 597326 R-MMU-965079 https://reactome.org/PathwayBrowser/#/R-MMU-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Mus musculus 597326 R-PFA-964970 https://reactome.org/PathwayBrowser/#/R-PFA-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Plasmodium falciparum 597326 R-RNO-964970 https://reactome.org/PathwayBrowser/#/R-RNO-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Rattus norvegicus 597326 R-RNO-965019 https://reactome.org/PathwayBrowser/#/R-RNO-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Rattus norvegicus 597326 R-RNO-965079 https://reactome.org/PathwayBrowser/#/R-RNO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Rattus norvegicus 597326 R-SCE-964970 https://reactome.org/PathwayBrowser/#/R-SCE-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Saccharomyces cerevisiae 597326 R-SCE-965019 https://reactome.org/PathwayBrowser/#/R-SCE-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Saccharomyces cerevisiae 597326 R-SCE-965079 https://reactome.org/PathwayBrowser/#/R-SCE-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Saccharomyces cerevisiae 597326 R-SPO-964970 https://reactome.org/PathwayBrowser/#/R-SPO-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Schizosaccharomyces pombe 597326 R-SPO-965019 https://reactome.org/PathwayBrowser/#/R-SPO-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Schizosaccharomyces pombe 597326 R-SPO-965079 https://reactome.org/PathwayBrowser/#/R-SPO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Schizosaccharomyces pombe 597326 R-SSC-964970 https://reactome.org/PathwayBrowser/#/R-SSC-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Sus scrofa 597326 R-SSC-965019 https://reactome.org/PathwayBrowser/#/R-SSC-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Sus scrofa 597326 R-SSC-965079 https://reactome.org/PathwayBrowser/#/R-SSC-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Sus scrofa 597326 R-XTR-964970 https://reactome.org/PathwayBrowser/#/R-XTR-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Xenopus tropicalis 597326 R-XTR-965019 https://reactome.org/PathwayBrowser/#/R-XTR-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Xenopus tropicalis 597326 R-XTR-965079 https://reactome.org/PathwayBrowser/#/R-XTR-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Xenopus tropicalis 59776 R-BTA-163741 https://reactome.org/PathwayBrowser/#/R-BTA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Bos taurus 59776 R-BTA-163751 https://reactome.org/PathwayBrowser/#/R-BTA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Bos taurus 59776 R-BTA-163764 https://reactome.org/PathwayBrowser/#/R-BTA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 59776 R-BTA-6787321 https://reactome.org/PathwayBrowser/#/R-BTA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Bos taurus 59776 R-BTA-70349 https://reactome.org/PathwayBrowser/#/R-BTA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Bos taurus 59776 R-BTA-70449 https://reactome.org/PathwayBrowser/#/R-BTA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Bos taurus 59776 R-BTA-70454 https://reactome.org/PathwayBrowser/#/R-BTA-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Bos taurus 59776 R-BTA-70481 https://reactome.org/PathwayBrowser/#/R-BTA-70481 TPI1 isomerizes GA3P to DHAP IEA Bos taurus 59776 R-BTA-70482 https://reactome.org/PathwayBrowser/#/R-BTA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Bos taurus 59776 R-BTA-71324 https://reactome.org/PathwayBrowser/#/R-BTA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 59776 R-BTA-71334 https://reactome.org/PathwayBrowser/#/R-BTA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Bos taurus 59776 R-BTA-71335 https://reactome.org/PathwayBrowser/#/R-BTA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Bos taurus 59776 R-BTA-71495 https://reactome.org/PathwayBrowser/#/R-BTA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Bos taurus 59776 R-BTA-71496 https://reactome.org/PathwayBrowser/#/R-BTA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 59776 R-CEL-163741 https://reactome.org/PathwayBrowser/#/R-CEL-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Caenorhabditis elegans 59776 R-CEL-163751 https://reactome.org/PathwayBrowser/#/R-CEL-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Caenorhabditis elegans 59776 R-CEL-163764 https://reactome.org/PathwayBrowser/#/R-CEL-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 59776 R-CEL-6787321 https://reactome.org/PathwayBrowser/#/R-CEL-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Caenorhabditis elegans 59776 R-CEL-70349 https://reactome.org/PathwayBrowser/#/R-CEL-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 59776 R-CEL-70449 https://reactome.org/PathwayBrowser/#/R-CEL-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Caenorhabditis elegans 59776 R-CEL-70454 https://reactome.org/PathwayBrowser/#/R-CEL-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 59776 R-CEL-70481 https://reactome.org/PathwayBrowser/#/R-CEL-70481 TPI1 isomerizes GA3P to DHAP IEA Caenorhabditis elegans 59776 R-CEL-70482 https://reactome.org/PathwayBrowser/#/R-CEL-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Caenorhabditis elegans 59776 R-CEL-71324 https://reactome.org/PathwayBrowser/#/R-CEL-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 59776 R-CEL-71334 https://reactome.org/PathwayBrowser/#/R-CEL-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Caenorhabditis elegans 59776 R-CEL-71335 https://reactome.org/PathwayBrowser/#/R-CEL-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Caenorhabditis elegans 59776 R-CEL-71495 https://reactome.org/PathwayBrowser/#/R-CEL-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Caenorhabditis elegans 59776 R-CEL-71496 https://reactome.org/PathwayBrowser/#/R-CEL-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 59776 R-CFA-163741 https://reactome.org/PathwayBrowser/#/R-CFA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Canis familiaris 59776 R-CFA-163751 https://reactome.org/PathwayBrowser/#/R-CFA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Canis familiaris 59776 R-CFA-163764 https://reactome.org/PathwayBrowser/#/R-CFA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 59776 R-CFA-6787321 https://reactome.org/PathwayBrowser/#/R-CFA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Canis familiaris 59776 R-CFA-70349 https://reactome.org/PathwayBrowser/#/R-CFA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Canis familiaris 59776 R-CFA-70449 https://reactome.org/PathwayBrowser/#/R-CFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Canis familiaris 59776 R-CFA-70454 https://reactome.org/PathwayBrowser/#/R-CFA-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Canis familiaris 59776 R-CFA-70481 https://reactome.org/PathwayBrowser/#/R-CFA-70481 TPI1 isomerizes GA3P to DHAP IEA Canis familiaris 59776 R-CFA-70482 https://reactome.org/PathwayBrowser/#/R-CFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Canis familiaris 59776 R-CFA-71324 https://reactome.org/PathwayBrowser/#/R-CFA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 59776 R-CFA-71334 https://reactome.org/PathwayBrowser/#/R-CFA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Canis familiaris 59776 R-CFA-71335 https://reactome.org/PathwayBrowser/#/R-CFA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Canis familiaris 59776 R-CFA-71495 https://reactome.org/PathwayBrowser/#/R-CFA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Canis familiaris 59776 R-CFA-71496 https://reactome.org/PathwayBrowser/#/R-CFA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 59776 R-DDI-163764 https://reactome.org/PathwayBrowser/#/R-DDI-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 59776 R-DDI-70349 https://reactome.org/PathwayBrowser/#/R-DDI-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 59776 R-DDI-70449 https://reactome.org/PathwayBrowser/#/R-DDI-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Dictyostelium discoideum 59776 R-DDI-70454 https://reactome.org/PathwayBrowser/#/R-DDI-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 59776 R-DDI-70481 https://reactome.org/PathwayBrowser/#/R-DDI-70481 TPI1 isomerizes GA3P to DHAP IEA Dictyostelium discoideum 59776 R-DDI-70482 https://reactome.org/PathwayBrowser/#/R-DDI-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Dictyostelium discoideum 59776 R-DDI-71334 https://reactome.org/PathwayBrowser/#/R-DDI-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Dictyostelium discoideum 59776 R-DDI-71495 https://reactome.org/PathwayBrowser/#/R-DDI-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Dictyostelium discoideum 59776 R-DDI-71496 https://reactome.org/PathwayBrowser/#/R-DDI-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Dictyostelium discoideum 59776 R-DME-163741 https://reactome.org/PathwayBrowser/#/R-DME-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Drosophila melanogaster 59776 R-DME-163751 https://reactome.org/PathwayBrowser/#/R-DME-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Drosophila melanogaster 59776 R-DME-163764 https://reactome.org/PathwayBrowser/#/R-DME-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 59776 R-DME-6787321 https://reactome.org/PathwayBrowser/#/R-DME-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Drosophila melanogaster 59776 R-DME-70449 https://reactome.org/PathwayBrowser/#/R-DME-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Drosophila melanogaster 59776 R-DME-70454 https://reactome.org/PathwayBrowser/#/R-DME-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 59776 R-DME-70481 https://reactome.org/PathwayBrowser/#/R-DME-70481 TPI1 isomerizes GA3P to DHAP IEA Drosophila melanogaster 59776 R-DME-70482 https://reactome.org/PathwayBrowser/#/R-DME-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Drosophila melanogaster 59776 R-DME-71324 https://reactome.org/PathwayBrowser/#/R-DME-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 59776 R-DME-71334 https://reactome.org/PathwayBrowser/#/R-DME-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Drosophila melanogaster 59776 R-DME-71335 https://reactome.org/PathwayBrowser/#/R-DME-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Drosophila melanogaster 59776 R-DME-71495 https://reactome.org/PathwayBrowser/#/R-DME-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Drosophila melanogaster 59776 R-DME-71496 https://reactome.org/PathwayBrowser/#/R-DME-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 59776 R-DRE-163764 https://reactome.org/PathwayBrowser/#/R-DRE-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Danio rerio 59776 R-DRE-6787321 https://reactome.org/PathwayBrowser/#/R-DRE-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Danio rerio 59776 R-DRE-70349 https://reactome.org/PathwayBrowser/#/R-DRE-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Danio rerio 59776 R-DRE-70449 https://reactome.org/PathwayBrowser/#/R-DRE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Danio rerio 59776 R-DRE-70454 https://reactome.org/PathwayBrowser/#/R-DRE-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Danio rerio 59776 R-DRE-70481 https://reactome.org/PathwayBrowser/#/R-DRE-70481 TPI1 isomerizes GA3P to DHAP IEA Danio rerio 59776 R-DRE-70482 https://reactome.org/PathwayBrowser/#/R-DRE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Danio rerio 59776 R-DRE-71334 https://reactome.org/PathwayBrowser/#/R-DRE-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Danio rerio 59776 R-DRE-71495 https://reactome.org/PathwayBrowser/#/R-DRE-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Danio rerio 59776 R-DRE-71496 https://reactome.org/PathwayBrowser/#/R-DRE-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Danio rerio 59776 R-GGA-163741 https://reactome.org/PathwayBrowser/#/R-GGA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Gallus gallus 59776 R-GGA-163751 https://reactome.org/PathwayBrowser/#/R-GGA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Gallus gallus 59776 R-GGA-163764 https://reactome.org/PathwayBrowser/#/R-GGA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 59776 R-GGA-352914 https://reactome.org/PathwayBrowser/#/R-GGA-352914 glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate TAS Gallus gallus 59776 R-GGA-352921 https://reactome.org/PathwayBrowser/#/R-GGA-352921 1,3-bisphosphoglycerate + NADH + H+ <=> glyceraldehyde 3-phosphate + NAD+ + phosphate TAS Gallus gallus 59776 R-GGA-352927 https://reactome.org/PathwayBrowser/#/R-GGA-352927 dihydroxyacetone phosphate <=> glyceraldehyde 3-phosphate TAS Gallus gallus 59776 R-GGA-352946 https://reactome.org/PathwayBrowser/#/R-GGA-352946 fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate TAS Gallus gallus 59776 R-GGA-352956 https://reactome.org/PathwayBrowser/#/R-GGA-352956 glyceraldehyde 3-phosphate + NAD+ + phosphate <=> 1,3-bisphosphoglycerate + NADH + H+ TAS Gallus gallus 59776 R-GGA-352961 https://reactome.org/PathwayBrowser/#/R-GGA-352961 dihydroxyacetone phosphate + glyceraldehyde 3-phosphate <=> fructose 1,6-bisphosphate TAS Gallus gallus 59776 R-GGA-6787321 https://reactome.org/PathwayBrowser/#/R-GGA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Gallus gallus 59776 R-GGA-70349 https://reactome.org/PathwayBrowser/#/R-GGA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Gallus gallus 59776 R-GGA-70449 https://reactome.org/PathwayBrowser/#/R-GGA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Gallus gallus 59776 R-GGA-70454 https://reactome.org/PathwayBrowser/#/R-GGA-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Gallus gallus 59776 R-GGA-70481 https://reactome.org/PathwayBrowser/#/R-GGA-70481 TPI1 isomerizes GA3P to DHAP IEA Gallus gallus 59776 R-GGA-70482 https://reactome.org/PathwayBrowser/#/R-GGA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Gallus gallus 59776 R-GGA-71324 https://reactome.org/PathwayBrowser/#/R-GGA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 59776 R-GGA-71334 https://reactome.org/PathwayBrowser/#/R-GGA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Gallus gallus 59776 R-GGA-71335 https://reactome.org/PathwayBrowser/#/R-GGA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Gallus gallus 59776 R-GGA-71495 https://reactome.org/PathwayBrowser/#/R-GGA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Gallus gallus 59776 R-GGA-71496 https://reactome.org/PathwayBrowser/#/R-GGA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 59776 R-HSA-163741 https://reactome.org/PathwayBrowser/#/R-HSA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate TAS Homo sapiens 59776 R-HSA-163751 https://reactome.org/PathwayBrowser/#/R-HSA-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate TAS Homo sapiens 59776 R-HSA-163764 https://reactome.org/PathwayBrowser/#/R-HSA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 59776 R-HSA-5659989 https://reactome.org/PathwayBrowser/#/R-HSA-5659989 Defective TALDO1 does not transform SH7P, GA3P to Fru(6)P, E4P TAS Homo sapiens 59776 R-HSA-6787321 https://reactome.org/PathwayBrowser/#/R-HSA-6787321 DERA cleaves dR5P to GA3P and CH3CHO TAS Homo sapiens 59776 R-HSA-70349 https://reactome.org/PathwayBrowser/#/R-HSA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate TAS Homo sapiens 59776 R-HSA-70449 https://reactome.org/PathwayBrowser/#/R-HSA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ TAS Homo sapiens 59776 R-HSA-70454 https://reactome.org/PathwayBrowser/#/R-HSA-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate TAS Homo sapiens 59776 R-HSA-70481 https://reactome.org/PathwayBrowser/#/R-HSA-70481 TPI1 isomerizes GA3P to DHAP TAS Homo sapiens 59776 R-HSA-70482 https://reactome.org/PathwayBrowser/#/R-HSA-70482 GAPDH tetramers reduce 1,3BPG to GA3P TAS Homo sapiens 59776 R-HSA-71324 https://reactome.org/PathwayBrowser/#/R-HSA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 59776 R-HSA-71334 https://reactome.org/PathwayBrowser/#/R-HSA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate TAS Homo sapiens 59776 R-HSA-71335 https://reactome.org/PathwayBrowser/#/R-HSA-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate TAS Homo sapiens 59776 R-HSA-71495 https://reactome.org/PathwayBrowser/#/R-HSA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP TAS Homo sapiens 59776 R-HSA-71496 https://reactome.org/PathwayBrowser/#/R-HSA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 59776 R-MMU-163741 https://reactome.org/PathwayBrowser/#/R-MMU-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Mus musculus 59776 R-MMU-163751 https://reactome.org/PathwayBrowser/#/R-MMU-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Mus musculus 59776 R-MMU-163764 https://reactome.org/PathwayBrowser/#/R-MMU-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 59776 R-MMU-6787321 https://reactome.org/PathwayBrowser/#/R-MMU-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Mus musculus 59776 R-MMU-70349 https://reactome.org/PathwayBrowser/#/R-MMU-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Mus musculus 59776 R-MMU-70449 https://reactome.org/PathwayBrowser/#/R-MMU-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Mus musculus 59776 R-MMU-70454 https://reactome.org/PathwayBrowser/#/R-MMU-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Mus musculus 59776 R-MMU-70481 https://reactome.org/PathwayBrowser/#/R-MMU-70481 TPI1 isomerizes GA3P to DHAP IEA Mus musculus 59776 R-MMU-70482 https://reactome.org/PathwayBrowser/#/R-MMU-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Mus musculus 59776 R-MMU-71324 https://reactome.org/PathwayBrowser/#/R-MMU-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 59776 R-MMU-71334 https://reactome.org/PathwayBrowser/#/R-MMU-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Mus musculus 59776 R-MMU-71335 https://reactome.org/PathwayBrowser/#/R-MMU-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Mus musculus 59776 R-MMU-71495 https://reactome.org/PathwayBrowser/#/R-MMU-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Mus musculus 59776 R-MMU-71496 https://reactome.org/PathwayBrowser/#/R-MMU-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 59776 R-PFA-70449 https://reactome.org/PathwayBrowser/#/R-PFA-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Plasmodium falciparum 59776 R-PFA-70454 https://reactome.org/PathwayBrowser/#/R-PFA-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Plasmodium falciparum 59776 R-PFA-70481 https://reactome.org/PathwayBrowser/#/R-PFA-70481 TPI1 isomerizes GA3P to DHAP IEA Plasmodium falciparum 59776 R-PFA-70482 https://reactome.org/PathwayBrowser/#/R-PFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Plasmodium falciparum 59776 R-PFA-71495 https://reactome.org/PathwayBrowser/#/R-PFA-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Plasmodium falciparum 59776 R-PFA-71496 https://reactome.org/PathwayBrowser/#/R-PFA-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Plasmodium falciparum 59776 R-RNO-163741 https://reactome.org/PathwayBrowser/#/R-RNO-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Rattus norvegicus 59776 R-RNO-163751 https://reactome.org/PathwayBrowser/#/R-RNO-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Rattus norvegicus 59776 R-RNO-163764 https://reactome.org/PathwayBrowser/#/R-RNO-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 59776 R-RNO-6787321 https://reactome.org/PathwayBrowser/#/R-RNO-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Rattus norvegicus 59776 R-RNO-70349 https://reactome.org/PathwayBrowser/#/R-RNO-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 59776 R-RNO-70449 https://reactome.org/PathwayBrowser/#/R-RNO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Rattus norvegicus 59776 R-RNO-70454 https://reactome.org/PathwayBrowser/#/R-RNO-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 59776 R-RNO-70481 https://reactome.org/PathwayBrowser/#/R-RNO-70481 TPI1 isomerizes GA3P to DHAP IEA Rattus norvegicus 59776 R-RNO-70482 https://reactome.org/PathwayBrowser/#/R-RNO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Rattus norvegicus 59776 R-RNO-71324 https://reactome.org/PathwayBrowser/#/R-RNO-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 59776 R-RNO-71334 https://reactome.org/PathwayBrowser/#/R-RNO-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Rattus norvegicus 59776 R-RNO-71335 https://reactome.org/PathwayBrowser/#/R-RNO-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Rattus norvegicus 59776 R-RNO-71495 https://reactome.org/PathwayBrowser/#/R-RNO-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Rattus norvegicus 59776 R-RNO-71496 https://reactome.org/PathwayBrowser/#/R-RNO-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 59776 R-SCE-163764 https://reactome.org/PathwayBrowser/#/R-SCE-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Saccharomyces cerevisiae 59776 R-SCE-70349 https://reactome.org/PathwayBrowser/#/R-SCE-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Saccharomyces cerevisiae 59776 R-SCE-70449 https://reactome.org/PathwayBrowser/#/R-SCE-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Saccharomyces cerevisiae 59776 R-SCE-70454 https://reactome.org/PathwayBrowser/#/R-SCE-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Saccharomyces cerevisiae 59776 R-SCE-70481 https://reactome.org/PathwayBrowser/#/R-SCE-70481 TPI1 isomerizes GA3P to DHAP IEA Saccharomyces cerevisiae 59776 R-SCE-70482 https://reactome.org/PathwayBrowser/#/R-SCE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Saccharomyces cerevisiae 59776 R-SCE-71334 https://reactome.org/PathwayBrowser/#/R-SCE-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Saccharomyces cerevisiae 59776 R-SPO-163764 https://reactome.org/PathwayBrowser/#/R-SPO-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Schizosaccharomyces pombe 59776 R-SPO-70349 https://reactome.org/PathwayBrowser/#/R-SPO-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Schizosaccharomyces pombe 59776 R-SPO-70449 https://reactome.org/PathwayBrowser/#/R-SPO-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Schizosaccharomyces pombe 59776 R-SPO-70454 https://reactome.org/PathwayBrowser/#/R-SPO-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Schizosaccharomyces pombe 59776 R-SPO-70481 https://reactome.org/PathwayBrowser/#/R-SPO-70481 TPI1 isomerizes GA3P to DHAP IEA Schizosaccharomyces pombe 59776 R-SPO-70482 https://reactome.org/PathwayBrowser/#/R-SPO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Schizosaccharomyces pombe 59776 R-SPO-71334 https://reactome.org/PathwayBrowser/#/R-SPO-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Schizosaccharomyces pombe 59776 R-SSC-163741 https://reactome.org/PathwayBrowser/#/R-SSC-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Sus scrofa 59776 R-SSC-163751 https://reactome.org/PathwayBrowser/#/R-SSC-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Sus scrofa 59776 R-SSC-163764 https://reactome.org/PathwayBrowser/#/R-SSC-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 59776 R-SSC-6787321 https://reactome.org/PathwayBrowser/#/R-SSC-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Sus scrofa 59776 R-SSC-70349 https://reactome.org/PathwayBrowser/#/R-SSC-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Sus scrofa 59776 R-SSC-70449 https://reactome.org/PathwayBrowser/#/R-SSC-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Sus scrofa 59776 R-SSC-70454 https://reactome.org/PathwayBrowser/#/R-SSC-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Sus scrofa 59776 R-SSC-70481 https://reactome.org/PathwayBrowser/#/R-SSC-70481 TPI1 isomerizes GA3P to DHAP IEA Sus scrofa 59776 R-SSC-70482 https://reactome.org/PathwayBrowser/#/R-SSC-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Sus scrofa 59776 R-SSC-71324 https://reactome.org/PathwayBrowser/#/R-SSC-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 59776 R-SSC-71334 https://reactome.org/PathwayBrowser/#/R-SSC-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Sus scrofa 59776 R-SSC-71335 https://reactome.org/PathwayBrowser/#/R-SSC-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Sus scrofa 59776 R-SSC-71495 https://reactome.org/PathwayBrowser/#/R-SSC-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Sus scrofa 59776 R-SSC-71496 https://reactome.org/PathwayBrowser/#/R-SSC-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 59776 R-XTR-163741 https://reactome.org/PathwayBrowser/#/R-XTR-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Xenopus tropicalis 59776 R-XTR-163751 https://reactome.org/PathwayBrowser/#/R-XTR-163751 D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate IEA Xenopus tropicalis 59776 R-XTR-163764 https://reactome.org/PathwayBrowser/#/R-XTR-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 59776 R-XTR-6787321 https://reactome.org/PathwayBrowser/#/R-XTR-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Xenopus tropicalis 59776 R-XTR-70449 https://reactome.org/PathwayBrowser/#/R-XTR-70449 D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ IEA Xenopus tropicalis 59776 R-XTR-70454 https://reactome.org/PathwayBrowser/#/R-XTR-70454 dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 59776 R-XTR-70481 https://reactome.org/PathwayBrowser/#/R-XTR-70481 TPI1 isomerizes GA3P to DHAP IEA Xenopus tropicalis 59776 R-XTR-70482 https://reactome.org/PathwayBrowser/#/R-XTR-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Xenopus tropicalis 59776 R-XTR-71324 https://reactome.org/PathwayBrowser/#/R-XTR-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 59776 R-XTR-71334 https://reactome.org/PathwayBrowser/#/R-XTR-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Xenopus tropicalis 59776 R-XTR-71335 https://reactome.org/PathwayBrowser/#/R-XTR-71335 xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate IEA Xenopus tropicalis 59776 R-XTR-71495 https://reactome.org/PathwayBrowser/#/R-XTR-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Xenopus tropicalis 59776 R-XTR-71496 https://reactome.org/PathwayBrowser/#/R-XTR-71496 D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 59789 R-BTA-1483174 https://reactome.org/PathwayBrowser/#/R-BTA-1483174 PE is methylated to PC by PEMT IEA Bos taurus 59789 R-BTA-158609 https://reactome.org/PathwayBrowser/#/R-BTA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Bos taurus 59789 R-BTA-174391 https://reactome.org/PathwayBrowser/#/R-BTA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Bos taurus 59789 R-BTA-175983 https://reactome.org/PathwayBrowser/#/R-BTA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Bos taurus 59789 R-BTA-175987 https://reactome.org/PathwayBrowser/#/R-BTA-175987 NNMT transfers CH3 from AdoMet to PY IEA Bos taurus 59789 R-BTA-191790 https://reactome.org/PathwayBrowser/#/R-BTA-191790 Loading and methylation of Sm proteins onto SMN Complexes IEA Bos taurus 59789 R-BTA-209821 https://reactome.org/PathwayBrowser/#/R-BTA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Bos taurus 59789 R-BTA-209903 https://reactome.org/PathwayBrowser/#/R-BTA-209903 Noradrenaline is converted to adrenaline IEA Bos taurus 59789 R-BTA-212263 https://reactome.org/PathwayBrowser/#/R-BTA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Bos taurus 59789 R-BTA-212269 https://reactome.org/PathwayBrowser/#/R-BTA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Bos taurus 59789 R-BTA-2162186 https://reactome.org/PathwayBrowser/#/R-BTA-2162186 COQ3 methylates DeMQ10H2 IEA Bos taurus 59789 R-BTA-2162188 https://reactome.org/PathwayBrowser/#/R-BTA-2162188 COQ5 methylates MDMQ10H2 IEA Bos taurus 59789 R-BTA-2162193 https://reactome.org/PathwayBrowser/#/R-BTA-2162193 COQ3 methylates DHDB IEA Bos taurus 59789 R-BTA-2301205 https://reactome.org/PathwayBrowser/#/R-BTA-2301205 SETD8 monomethylates histone H4 IEA Bos taurus 59789 R-BTA-3149518 https://reactome.org/PathwayBrowser/#/R-BTA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Bos taurus 59789 R-BTA-3222237 https://reactome.org/PathwayBrowser/#/R-BTA-3222237 SMYD2 methylates TP53 IEA Bos taurus 59789 R-BTA-3240295 https://reactome.org/PathwayBrowser/#/R-BTA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Bos taurus 59789 R-BTA-3364026 https://reactome.org/PathwayBrowser/#/R-BTA-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Bos taurus 59789 R-BTA-351222 https://reactome.org/PathwayBrowser/#/R-BTA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Bos taurus 59789 R-BTA-3788745 https://reactome.org/PathwayBrowser/#/R-BTA-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Bos taurus 59789 R-BTA-3788748 https://reactome.org/PathwayBrowser/#/R-BTA-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Bos taurus 59789 R-BTA-379387 https://reactome.org/PathwayBrowser/#/R-BTA-379387 COMT transfers Met to DA to form 3MT IEA Bos taurus 59789 R-BTA-379464 https://reactome.org/PathwayBrowser/#/R-BTA-379464 COMT transfers Met to DOPAC to form HVA IEA Bos taurus 59789 R-BTA-427527 https://reactome.org/PathwayBrowser/#/R-BTA-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Bos taurus 59789 R-BTA-4827382 https://reactome.org/PathwayBrowser/#/R-BTA-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Bos taurus 59789 R-BTA-4827383 https://reactome.org/PathwayBrowser/#/R-BTA-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Bos taurus 59789 R-BTA-5159245 https://reactome.org/PathwayBrowser/#/R-BTA-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Bos taurus 59789 R-BTA-5205798 https://reactome.org/PathwayBrowser/#/R-BTA-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Bos taurus 59789 R-BTA-5205799 https://reactome.org/PathwayBrowser/#/R-BTA-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Bos taurus 59789 R-BTA-5205820 https://reactome.org/PathwayBrowser/#/R-BTA-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Bos taurus 59789 R-BTA-5205822 https://reactome.org/PathwayBrowser/#/R-BTA-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 IEA Bos taurus 59789 R-BTA-5205824 https://reactome.org/PathwayBrowser/#/R-BTA-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Bos taurus 59789 R-BTA-5205861 https://reactome.org/PathwayBrowser/#/R-BTA-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Bos taurus 59789 R-BTA-5205867 https://reactome.org/PathwayBrowser/#/R-BTA-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Bos taurus 59789 R-BTA-5216234 https://reactome.org/PathwayBrowser/#/R-BTA-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Bos taurus 59789 R-BTA-5218952 https://reactome.org/PathwayBrowser/#/R-BTA-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Bos taurus 59789 R-BTA-5229010 https://reactome.org/PathwayBrowser/#/R-BTA-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) IEA Bos taurus 59789 R-BTA-5229203 https://reactome.org/PathwayBrowser/#/R-BTA-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Bos taurus 59789 R-BTA-5244692 https://reactome.org/PathwayBrowser/#/R-BTA-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Bos taurus 59789 R-BTA-5358484 https://reactome.org/PathwayBrowser/#/R-BTA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Bos taurus 59789 R-BTA-5358494 https://reactome.org/PathwayBrowser/#/R-BTA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Bos taurus 59789 R-BTA-5359451 https://reactome.org/PathwayBrowser/#/R-BTA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Bos taurus 59789 R-BTA-5423038 https://reactome.org/PathwayBrowser/#/R-BTA-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Bos taurus 59789 R-BTA-5603114 https://reactome.org/PathwayBrowser/#/R-BTA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Bos taurus 59789 R-BTA-5634729 https://reactome.org/PathwayBrowser/#/R-BTA-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Bos taurus 59789 R-BTA-5634750 https://reactome.org/PathwayBrowser/#/R-BTA-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Bos taurus 59789 R-BTA-5634802 https://reactome.org/PathwayBrowser/#/R-BTA-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Bos taurus 59789 R-BTA-5637686 https://reactome.org/PathwayBrowser/#/R-BTA-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Bos taurus 59789 R-BTA-5638141 https://reactome.org/PathwayBrowser/#/R-BTA-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) IEA Bos taurus 59789 R-BTA-5638157 https://reactome.org/PathwayBrowser/#/R-BTA-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Bos taurus 59789 R-BTA-5638332 https://reactome.org/PathwayBrowser/#/R-BTA-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Bos taurus 59789 R-BTA-5638333 https://reactome.org/PathwayBrowser/#/R-BTA-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Bos taurus 59789 R-BTA-5649764 https://reactome.org/PathwayBrowser/#/R-BTA-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Bos taurus 59789 R-BTA-5649799 https://reactome.org/PathwayBrowser/#/R-BTA-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Bos taurus 59789 R-BTA-5649800 https://reactome.org/PathwayBrowser/#/R-BTA-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Bos taurus 59789 R-BTA-5649801 https://reactome.org/PathwayBrowser/#/R-BTA-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Bos taurus 59789 R-BTA-5649802 https://reactome.org/PathwayBrowser/#/R-BTA-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Bos taurus 59789 R-BTA-5651654 https://reactome.org/PathwayBrowser/#/R-BTA-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Bos taurus 59789 R-BTA-5651657 https://reactome.org/PathwayBrowser/#/R-BTA-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Bos taurus 59789 R-BTA-5661117 https://reactome.org/PathwayBrowser/#/R-BTA-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Bos taurus 59789 R-BTA-5661126 https://reactome.org/PathwayBrowser/#/R-BTA-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Bos taurus 59789 R-BTA-5676966 https://reactome.org/PathwayBrowser/#/R-BTA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Bos taurus 59789 R-BTA-5682965 https://reactome.org/PathwayBrowser/#/R-BTA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Bos taurus 59789 R-BTA-5696213 https://reactome.org/PathwayBrowser/#/R-BTA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Bos taurus 59789 R-BTA-5696220 https://reactome.org/PathwayBrowser/#/R-BTA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Bos taurus 59789 R-BTA-6786205 https://reactome.org/PathwayBrowser/#/R-BTA-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Bos taurus 59789 R-BTA-6788650 https://reactome.org/PathwayBrowser/#/R-BTA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Bos taurus 59789 R-BTA-6793591 https://reactome.org/PathwayBrowser/#/R-BTA-6793591 LIAS synthesizes lipoyl-GCSH IEA Bos taurus 59789 R-BTA-6798317 https://reactome.org/PathwayBrowser/#/R-BTA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Bos taurus 59789 R-BTA-6800138 https://reactome.org/PathwayBrowser/#/R-BTA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Bos taurus 59789 R-BTA-6800149 https://reactome.org/PathwayBrowser/#/R-BTA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Bos taurus 59789 R-BTA-6804383 https://reactome.org/PathwayBrowser/#/R-BTA-6804383 PRMT5 methylates TP53 IEA Bos taurus 59789 R-BTA-6805730 https://reactome.org/PathwayBrowser/#/R-BTA-6805730 SETD9 methylates TP53 IEA Bos taurus 59789 R-BTA-6805740 https://reactome.org/PathwayBrowser/#/R-BTA-6805740 SETD8 methylates TP53 IEA Bos taurus 59789 R-BTA-6805755 https://reactome.org/PathwayBrowser/#/R-BTA-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Bos taurus 59789 R-BTA-71286 https://reactome.org/PathwayBrowser/#/R-BTA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Bos taurus 59789 R-BTA-77090 https://reactome.org/PathwayBrowser/#/R-BTA-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Bos taurus 59789 R-BTA-8855062 https://reactome.org/PathwayBrowser/#/R-BTA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Bos taurus 59789 R-BTA-8856945 https://reactome.org/PathwayBrowser/#/R-BTA-8856945 PP2A methylation by LCMT1 IEA Bos taurus 59789 R-BTA-8865237 https://reactome.org/PathwayBrowser/#/R-BTA-8865237 SETD6 methylates RELA in the NFkB complex IEA Bos taurus 59789 R-BTA-8876789 https://reactome.org/PathwayBrowser/#/R-BTA-8876789 CARNMT1 methylates CARN to Anserine IEA Bos taurus 59789 R-BTA-8879123 https://reactome.org/PathwayBrowser/#/R-BTA-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Bos taurus 59789 R-BTA-8931974 https://reactome.org/PathwayBrowser/#/R-BTA-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Bos taurus 59789 R-BTA-8932221 https://reactome.org/PathwayBrowser/#/R-BTA-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Bos taurus 59789 R-BTA-8932243 https://reactome.org/PathwayBrowser/#/R-BTA-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Bos taurus 59789 R-BTA-8932275 https://reactome.org/PathwayBrowser/#/R-BTA-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Bos taurus 59789 R-BTA-8932413 https://reactome.org/PathwayBrowser/#/R-BTA-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Bos taurus 59789 R-BTA-8934735 https://reactome.org/PathwayBrowser/#/R-BTA-8934735 PRMT1 arginine-methylates RUNX1 IEA Bos taurus 59789 R-BTA-8936481 https://reactome.org/PathwayBrowser/#/R-BTA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Bos taurus 59789 R-BTA-8936584 https://reactome.org/PathwayBrowser/#/R-BTA-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Bos taurus 59789 R-BTA-8936608 https://reactome.org/PathwayBrowser/#/R-BTA-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Bos taurus 59789 R-BTA-8936621 https://reactome.org/PathwayBrowser/#/R-BTA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Bos taurus 59789 R-BTA-8937016 https://reactome.org/PathwayBrowser/#/R-BTA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Bos taurus 59789 R-BTA-8937022 https://reactome.org/PathwayBrowser/#/R-BTA-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Bos taurus 59789 R-BTA-8937050 https://reactome.org/PathwayBrowser/#/R-BTA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Bos taurus 59789 R-BTA-8937113 https://reactome.org/PathwayBrowser/#/R-BTA-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Bos taurus 59789 R-BTA-8955010 https://reactome.org/PathwayBrowser/#/R-BTA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Bos taurus 59789 R-BTA-947535 https://reactome.org/PathwayBrowser/#/R-BTA-947535 Cyclisation of GTP to precursor Z IEA Bos taurus 59789 R-BTA-9632182 https://reactome.org/PathwayBrowser/#/R-BTA-9632182 PRMT1 methylates ESRs IEA Bos taurus 59789 R-BTA-9640254 https://reactome.org/PathwayBrowser/#/R-BTA-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Bos taurus 59789 R-BTA-9647977 https://reactome.org/PathwayBrowser/#/R-BTA-9647977 ICMT methylates S-Farn RAS proteins IEA Bos taurus 59789 R-BTA-9748979 https://reactome.org/PathwayBrowser/#/R-BTA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Bos taurus 59789 R-BTA-9748983 https://reactome.org/PathwayBrowser/#/R-BTA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Bos taurus 59789 R-BTA-9854315 https://reactome.org/PathwayBrowser/#/R-BTA-9854315 CSKMT methylates Citrate Synthase IEA Bos taurus 59789 R-CEL-175987 https://reactome.org/PathwayBrowser/#/R-CEL-175987 NNMT transfers CH3 from AdoMet to PY IEA Caenorhabditis elegans 59789 R-CEL-209903 https://reactome.org/PathwayBrowser/#/R-CEL-209903 Noradrenaline is converted to adrenaline IEA Caenorhabditis elegans 59789 R-CEL-2162186 https://reactome.org/PathwayBrowser/#/R-CEL-2162186 COQ3 methylates DeMQ10H2 IEA Caenorhabditis elegans 59789 R-CEL-2162188 https://reactome.org/PathwayBrowser/#/R-CEL-2162188 COQ5 methylates MDMQ10H2 IEA Caenorhabditis elegans 59789 R-CEL-2162193 https://reactome.org/PathwayBrowser/#/R-CEL-2162193 COQ3 methylates DHDB IEA Caenorhabditis elegans 59789 R-CEL-2301205 https://reactome.org/PathwayBrowser/#/R-CEL-2301205 SETD8 monomethylates histone H4 IEA Caenorhabditis elegans 59789 R-CEL-3149518 https://reactome.org/PathwayBrowser/#/R-CEL-3149518 MTRR reduces cob(II)alamin to meCbl IEA Caenorhabditis elegans 59789 R-CEL-3240295 https://reactome.org/PathwayBrowser/#/R-CEL-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Caenorhabditis elegans 59789 R-CEL-351222 https://reactome.org/PathwayBrowser/#/R-CEL-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Caenorhabditis elegans 59789 R-CEL-4827382 https://reactome.org/PathwayBrowser/#/R-CEL-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Caenorhabditis elegans 59789 R-CEL-4827383 https://reactome.org/PathwayBrowser/#/R-CEL-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Caenorhabditis elegans 59789 R-CEL-5159245 https://reactome.org/PathwayBrowser/#/R-CEL-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Caenorhabditis elegans 59789 R-CEL-5205798 https://reactome.org/PathwayBrowser/#/R-CEL-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Caenorhabditis elegans 59789 R-CEL-5205867 https://reactome.org/PathwayBrowser/#/R-CEL-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Caenorhabditis elegans 59789 R-CEL-5218952 https://reactome.org/PathwayBrowser/#/R-CEL-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Caenorhabditis elegans 59789 R-CEL-5244692 https://reactome.org/PathwayBrowser/#/R-CEL-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Caenorhabditis elegans 59789 R-CEL-5358484 https://reactome.org/PathwayBrowser/#/R-CEL-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Caenorhabditis elegans 59789 R-CEL-5358494 https://reactome.org/PathwayBrowser/#/R-CEL-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Caenorhabditis elegans 59789 R-CEL-5359451 https://reactome.org/PathwayBrowser/#/R-CEL-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Caenorhabditis elegans 59789 R-CEL-5423038 https://reactome.org/PathwayBrowser/#/R-CEL-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Caenorhabditis elegans 59789 R-CEL-5634802 https://reactome.org/PathwayBrowser/#/R-CEL-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Caenorhabditis elegans 59789 R-CEL-5637686 https://reactome.org/PathwayBrowser/#/R-CEL-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Caenorhabditis elegans 59789 R-CEL-5638157 https://reactome.org/PathwayBrowser/#/R-CEL-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Caenorhabditis elegans 59789 R-CEL-5649764 https://reactome.org/PathwayBrowser/#/R-CEL-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Caenorhabditis elegans 59789 R-CEL-5649799 https://reactome.org/PathwayBrowser/#/R-CEL-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Caenorhabditis elegans 59789 R-CEL-5649801 https://reactome.org/PathwayBrowser/#/R-CEL-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Caenorhabditis elegans 59789 R-CEL-5661126 https://reactome.org/PathwayBrowser/#/R-CEL-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Caenorhabditis elegans 59789 R-CEL-5676966 https://reactome.org/PathwayBrowser/#/R-CEL-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Caenorhabditis elegans 59789 R-CEL-6788650 https://reactome.org/PathwayBrowser/#/R-CEL-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Caenorhabditis elegans 59789 R-CEL-6800138 https://reactome.org/PathwayBrowser/#/R-CEL-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Caenorhabditis elegans 59789 R-CEL-6800149 https://reactome.org/PathwayBrowser/#/R-CEL-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Caenorhabditis elegans 59789 R-CEL-77090 https://reactome.org/PathwayBrowser/#/R-CEL-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Caenorhabditis elegans 59789 R-CEL-8855062 https://reactome.org/PathwayBrowser/#/R-CEL-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Caenorhabditis elegans 59789 R-CEL-8856945 https://reactome.org/PathwayBrowser/#/R-CEL-8856945 PP2A methylation by LCMT1 IEA Caenorhabditis elegans 59789 R-CEL-8931858 https://reactome.org/PathwayBrowser/#/R-CEL-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Caenorhabditis elegans 59789 R-CEL-8931974 https://reactome.org/PathwayBrowser/#/R-CEL-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Caenorhabditis elegans 59789 R-CEL-8932276 https://reactome.org/PathwayBrowser/#/R-CEL-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Caenorhabditis elegans 59789 R-CEL-8932413 https://reactome.org/PathwayBrowser/#/R-CEL-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Caenorhabditis elegans 59789 R-CEL-8934735 https://reactome.org/PathwayBrowser/#/R-CEL-8934735 PRMT1 arginine-methylates RUNX1 IEA Caenorhabditis elegans 59789 R-CEL-8936481 https://reactome.org/PathwayBrowser/#/R-CEL-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Caenorhabditis elegans 59789 R-CEL-8936584 https://reactome.org/PathwayBrowser/#/R-CEL-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Caenorhabditis elegans 59789 R-CEL-8936608 https://reactome.org/PathwayBrowser/#/R-CEL-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Caenorhabditis elegans 59789 R-CEL-8936621 https://reactome.org/PathwayBrowser/#/R-CEL-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Caenorhabditis elegans 59789 R-CEL-8937016 https://reactome.org/PathwayBrowser/#/R-CEL-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Caenorhabditis elegans 59789 R-CEL-8937022 https://reactome.org/PathwayBrowser/#/R-CEL-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Caenorhabditis elegans 59789 R-CEL-8937050 https://reactome.org/PathwayBrowser/#/R-CEL-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Caenorhabditis elegans 59789 R-CEL-8937113 https://reactome.org/PathwayBrowser/#/R-CEL-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Caenorhabditis elegans 59789 R-CEL-947535 https://reactome.org/PathwayBrowser/#/R-CEL-947535 Cyclisation of GTP to precursor Z IEA Caenorhabditis elegans 59789 R-CEL-9647977 https://reactome.org/PathwayBrowser/#/R-CEL-9647977 ICMT methylates S-Farn RAS proteins IEA Caenorhabditis elegans 59789 R-CFA-1483174 https://reactome.org/PathwayBrowser/#/R-CFA-1483174 PE is methylated to PC by PEMT IEA Canis familiaris 59789 R-CFA-158609 https://reactome.org/PathwayBrowser/#/R-CFA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Canis familiaris 59789 R-CFA-174391 https://reactome.org/PathwayBrowser/#/R-CFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Canis familiaris 59789 R-CFA-175983 https://reactome.org/PathwayBrowser/#/R-CFA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Canis familiaris 59789 R-CFA-175987 https://reactome.org/PathwayBrowser/#/R-CFA-175987 NNMT transfers CH3 from AdoMet to PY IEA Canis familiaris 59789 R-CFA-191790 https://reactome.org/PathwayBrowser/#/R-CFA-191790 Loading and methylation of Sm proteins onto SMN Complexes IEA Canis familiaris 59789 R-CFA-209821 https://reactome.org/PathwayBrowser/#/R-CFA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Canis familiaris 59789 R-CFA-209903 https://reactome.org/PathwayBrowser/#/R-CFA-209903 Noradrenaline is converted to adrenaline IEA Canis familiaris 59789 R-CFA-212263 https://reactome.org/PathwayBrowser/#/R-CFA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Canis familiaris 59789 R-CFA-212269 https://reactome.org/PathwayBrowser/#/R-CFA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Canis familiaris 59789 R-CFA-2162186 https://reactome.org/PathwayBrowser/#/R-CFA-2162186 COQ3 methylates DeMQ10H2 IEA Canis familiaris 59789 R-CFA-2162188 https://reactome.org/PathwayBrowser/#/R-CFA-2162188 COQ5 methylates MDMQ10H2 IEA Canis familiaris 59789 R-CFA-2162193 https://reactome.org/PathwayBrowser/#/R-CFA-2162193 COQ3 methylates DHDB IEA Canis familiaris 59789 R-CFA-3149518 https://reactome.org/PathwayBrowser/#/R-CFA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Canis familiaris 59789 R-CFA-3222237 https://reactome.org/PathwayBrowser/#/R-CFA-3222237 SMYD2 methylates TP53 IEA Canis familiaris 59789 R-CFA-3240295 https://reactome.org/PathwayBrowser/#/R-CFA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Canis familiaris 59789 R-CFA-351222 https://reactome.org/PathwayBrowser/#/R-CFA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Canis familiaris 59789 R-CFA-3788745 https://reactome.org/PathwayBrowser/#/R-CFA-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Canis familiaris 59789 R-CFA-3788748 https://reactome.org/PathwayBrowser/#/R-CFA-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Canis familiaris 59789 R-CFA-379387 https://reactome.org/PathwayBrowser/#/R-CFA-379387 COMT transfers Met to DA to form 3MT IEA Canis familiaris 59789 R-CFA-379464 https://reactome.org/PathwayBrowser/#/R-CFA-379464 COMT transfers Met to DOPAC to form HVA IEA Canis familiaris 59789 R-CFA-427527 https://reactome.org/PathwayBrowser/#/R-CFA-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Canis familiaris 59789 R-CFA-4827382 https://reactome.org/PathwayBrowser/#/R-CFA-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Canis familiaris 59789 R-CFA-4827383 https://reactome.org/PathwayBrowser/#/R-CFA-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Canis familiaris 59789 R-CFA-5159245 https://reactome.org/PathwayBrowser/#/R-CFA-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Canis familiaris 59789 R-CFA-5205798 https://reactome.org/PathwayBrowser/#/R-CFA-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Canis familiaris 59789 R-CFA-5205799 https://reactome.org/PathwayBrowser/#/R-CFA-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Canis familiaris 59789 R-CFA-5205820 https://reactome.org/PathwayBrowser/#/R-CFA-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Canis familiaris 59789 R-CFA-5205822 https://reactome.org/PathwayBrowser/#/R-CFA-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 IEA Canis familiaris 59789 R-CFA-5205824 https://reactome.org/PathwayBrowser/#/R-CFA-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Canis familiaris 59789 R-CFA-5205861 https://reactome.org/PathwayBrowser/#/R-CFA-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Canis familiaris 59789 R-CFA-5205867 https://reactome.org/PathwayBrowser/#/R-CFA-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Canis familiaris 59789 R-CFA-5216234 https://reactome.org/PathwayBrowser/#/R-CFA-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Canis familiaris 59789 R-CFA-5218952 https://reactome.org/PathwayBrowser/#/R-CFA-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Canis familiaris 59789 R-CFA-5229010 https://reactome.org/PathwayBrowser/#/R-CFA-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) IEA Canis familiaris 59789 R-CFA-5229203 https://reactome.org/PathwayBrowser/#/R-CFA-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Canis familiaris 59789 R-CFA-5244692 https://reactome.org/PathwayBrowser/#/R-CFA-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Canis familiaris 59789 R-CFA-5358484 https://reactome.org/PathwayBrowser/#/R-CFA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Canis familiaris 59789 R-CFA-5358494 https://reactome.org/PathwayBrowser/#/R-CFA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Canis familiaris 59789 R-CFA-5359451 https://reactome.org/PathwayBrowser/#/R-CFA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Canis familiaris 59789 R-CFA-5603114 https://reactome.org/PathwayBrowser/#/R-CFA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Canis familiaris 59789 R-CFA-5634729 https://reactome.org/PathwayBrowser/#/R-CFA-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Canis familiaris 59789 R-CFA-5634750 https://reactome.org/PathwayBrowser/#/R-CFA-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Canis familiaris 59789 R-CFA-5634802 https://reactome.org/PathwayBrowser/#/R-CFA-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Canis familiaris 59789 R-CFA-5637686 https://reactome.org/PathwayBrowser/#/R-CFA-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Canis familiaris 59789 R-CFA-5638141 https://reactome.org/PathwayBrowser/#/R-CFA-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) IEA Canis familiaris 59789 R-CFA-5638157 https://reactome.org/PathwayBrowser/#/R-CFA-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Canis familiaris 59789 R-CFA-5638332 https://reactome.org/PathwayBrowser/#/R-CFA-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Canis familiaris 59789 R-CFA-5638333 https://reactome.org/PathwayBrowser/#/R-CFA-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Canis familiaris 59789 R-CFA-5649764 https://reactome.org/PathwayBrowser/#/R-CFA-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Canis familiaris 59789 R-CFA-5649799 https://reactome.org/PathwayBrowser/#/R-CFA-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Canis familiaris 59789 R-CFA-5649800 https://reactome.org/PathwayBrowser/#/R-CFA-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Canis familiaris 59789 R-CFA-5649801 https://reactome.org/PathwayBrowser/#/R-CFA-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Canis familiaris 59789 R-CFA-5649802 https://reactome.org/PathwayBrowser/#/R-CFA-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Canis familiaris 59789 R-CFA-5651654 https://reactome.org/PathwayBrowser/#/R-CFA-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Canis familiaris 59789 R-CFA-5651657 https://reactome.org/PathwayBrowser/#/R-CFA-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Canis familiaris 59789 R-CFA-5661117 https://reactome.org/PathwayBrowser/#/R-CFA-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Canis familiaris 59789 R-CFA-5661126 https://reactome.org/PathwayBrowser/#/R-CFA-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Canis familiaris 59789 R-CFA-5676966 https://reactome.org/PathwayBrowser/#/R-CFA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Canis familiaris 59789 R-CFA-5682965 https://reactome.org/PathwayBrowser/#/R-CFA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Canis familiaris 59789 R-CFA-6786205 https://reactome.org/PathwayBrowser/#/R-CFA-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Canis familiaris 59789 R-CFA-6793591 https://reactome.org/PathwayBrowser/#/R-CFA-6793591 LIAS synthesizes lipoyl-GCSH IEA Canis familiaris 59789 R-CFA-6798317 https://reactome.org/PathwayBrowser/#/R-CFA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Canis familiaris 59789 R-CFA-6800138 https://reactome.org/PathwayBrowser/#/R-CFA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Canis familiaris 59789 R-CFA-6800149 https://reactome.org/PathwayBrowser/#/R-CFA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Canis familiaris 59789 R-CFA-6804383 https://reactome.org/PathwayBrowser/#/R-CFA-6804383 PRMT5 methylates TP53 IEA Canis familiaris 59789 R-CFA-6805730 https://reactome.org/PathwayBrowser/#/R-CFA-6805730 SETD9 methylates TP53 IEA Canis familiaris 59789 R-CFA-6805755 https://reactome.org/PathwayBrowser/#/R-CFA-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Canis familiaris 59789 R-CFA-71286 https://reactome.org/PathwayBrowser/#/R-CFA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Canis familiaris 59789 R-CFA-77090 https://reactome.org/PathwayBrowser/#/R-CFA-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Canis familiaris 59789 R-CFA-8855062 https://reactome.org/PathwayBrowser/#/R-CFA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Canis familiaris 59789 R-CFA-8856945 https://reactome.org/PathwayBrowser/#/R-CFA-8856945 PP2A methylation by LCMT1 IEA Canis familiaris 59789 R-CFA-8865237 https://reactome.org/PathwayBrowser/#/R-CFA-8865237 SETD6 methylates RELA in the NFkB complex IEA Canis familiaris 59789 R-CFA-8876789 https://reactome.org/PathwayBrowser/#/R-CFA-8876789 CARNMT1 methylates CARN to Anserine IEA Canis familiaris 59789 R-CFA-8879123 https://reactome.org/PathwayBrowser/#/R-CFA-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Canis familiaris 59789 R-CFA-8931858 https://reactome.org/PathwayBrowser/#/R-CFA-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Canis familiaris 59789 R-CFA-8931974 https://reactome.org/PathwayBrowser/#/R-CFA-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Canis familiaris 59789 R-CFA-8932221 https://reactome.org/PathwayBrowser/#/R-CFA-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Canis familiaris 59789 R-CFA-8932243 https://reactome.org/PathwayBrowser/#/R-CFA-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Canis familiaris 59789 R-CFA-8932275 https://reactome.org/PathwayBrowser/#/R-CFA-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Canis familiaris 59789 R-CFA-8932276 https://reactome.org/PathwayBrowser/#/R-CFA-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Canis familiaris 59789 R-CFA-8932413 https://reactome.org/PathwayBrowser/#/R-CFA-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Canis familiaris 59789 R-CFA-8934735 https://reactome.org/PathwayBrowser/#/R-CFA-8934735 PRMT1 arginine-methylates RUNX1 IEA Canis familiaris 59789 R-CFA-8936481 https://reactome.org/PathwayBrowser/#/R-CFA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Canis familiaris 59789 R-CFA-8936584 https://reactome.org/PathwayBrowser/#/R-CFA-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Canis familiaris 59789 R-CFA-8936608 https://reactome.org/PathwayBrowser/#/R-CFA-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Canis familiaris 59789 R-CFA-8936621 https://reactome.org/PathwayBrowser/#/R-CFA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Canis familiaris 59789 R-CFA-8937016 https://reactome.org/PathwayBrowser/#/R-CFA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Canis familiaris 59789 R-CFA-8937022 https://reactome.org/PathwayBrowser/#/R-CFA-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Canis familiaris 59789 R-CFA-8937050 https://reactome.org/PathwayBrowser/#/R-CFA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Canis familiaris 59789 R-CFA-8937113 https://reactome.org/PathwayBrowser/#/R-CFA-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Canis familiaris 59789 R-CFA-8955010 https://reactome.org/PathwayBrowser/#/R-CFA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Canis familiaris 59789 R-CFA-947535 https://reactome.org/PathwayBrowser/#/R-CFA-947535 Cyclisation of GTP to precursor Z IEA Canis familiaris 59789 R-CFA-9632182 https://reactome.org/PathwayBrowser/#/R-CFA-9632182 PRMT1 methylates ESRs IEA Canis familiaris 59789 R-CFA-9640254 https://reactome.org/PathwayBrowser/#/R-CFA-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Canis familiaris 59789 R-CFA-9748979 https://reactome.org/PathwayBrowser/#/R-CFA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Canis familiaris 59789 R-CFA-9748983 https://reactome.org/PathwayBrowser/#/R-CFA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Canis familiaris 59789 R-CFA-9854315 https://reactome.org/PathwayBrowser/#/R-CFA-9854315 CSKMT methylates Citrate Synthase IEA Canis familiaris 59789 R-DDI-1483174 https://reactome.org/PathwayBrowser/#/R-DDI-1483174 PE is methylated to PC by PEMT IEA Dictyostelium discoideum 59789 R-DDI-174391 https://reactome.org/PathwayBrowser/#/R-DDI-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Dictyostelium discoideum 59789 R-DDI-209821 https://reactome.org/PathwayBrowser/#/R-DDI-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Dictyostelium discoideum 59789 R-DDI-2162186 https://reactome.org/PathwayBrowser/#/R-DDI-2162186 COQ3 methylates DeMQ10H2 IEA Dictyostelium discoideum 59789 R-DDI-2162188 https://reactome.org/PathwayBrowser/#/R-DDI-2162188 COQ5 methylates MDMQ10H2 IEA Dictyostelium discoideum 59789 R-DDI-2162193 https://reactome.org/PathwayBrowser/#/R-DDI-2162193 COQ3 methylates DHDB IEA Dictyostelium discoideum 59789 R-DDI-3149518 https://reactome.org/PathwayBrowser/#/R-DDI-3149518 MTRR reduces cob(II)alamin to meCbl IEA Dictyostelium discoideum 59789 R-DDI-351222 https://reactome.org/PathwayBrowser/#/R-DDI-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Dictyostelium discoideum 59789 R-DDI-427527 https://reactome.org/PathwayBrowser/#/R-DDI-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Dictyostelium discoideum 59789 R-DDI-4827382 https://reactome.org/PathwayBrowser/#/R-DDI-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Dictyostelium discoideum 59789 R-DDI-4827383 https://reactome.org/PathwayBrowser/#/R-DDI-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Dictyostelium discoideum 59789 R-DDI-5159245 https://reactome.org/PathwayBrowser/#/R-DDI-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Dictyostelium discoideum 59789 R-DDI-5205798 https://reactome.org/PathwayBrowser/#/R-DDI-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Dictyostelium discoideum 59789 R-DDI-5205799 https://reactome.org/PathwayBrowser/#/R-DDI-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Dictyostelium discoideum 59789 R-DDI-5205867 https://reactome.org/PathwayBrowser/#/R-DDI-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Dictyostelium discoideum 59789 R-DDI-5218952 https://reactome.org/PathwayBrowser/#/R-DDI-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Dictyostelium discoideum 59789 R-DDI-5244692 https://reactome.org/PathwayBrowser/#/R-DDI-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Dictyostelium discoideum 59789 R-DDI-5358484 https://reactome.org/PathwayBrowser/#/R-DDI-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Dictyostelium discoideum 59789 R-DDI-5358494 https://reactome.org/PathwayBrowser/#/R-DDI-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Dictyostelium discoideum 59789 R-DDI-5603114 https://reactome.org/PathwayBrowser/#/R-DDI-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Dictyostelium discoideum 59789 R-DDI-5637686 https://reactome.org/PathwayBrowser/#/R-DDI-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Dictyostelium discoideum 59789 R-DDI-5638157 https://reactome.org/PathwayBrowser/#/R-DDI-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Dictyostelium discoideum 59789 R-DDI-5638333 https://reactome.org/PathwayBrowser/#/R-DDI-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Dictyostelium discoideum 59789 R-DDI-5649764 https://reactome.org/PathwayBrowser/#/R-DDI-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Dictyostelium discoideum 59789 R-DDI-5649799 https://reactome.org/PathwayBrowser/#/R-DDI-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Dictyostelium discoideum 59789 R-DDI-5649800 https://reactome.org/PathwayBrowser/#/R-DDI-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Dictyostelium discoideum 59789 R-DDI-5649801 https://reactome.org/PathwayBrowser/#/R-DDI-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Dictyostelium discoideum 59789 R-DDI-5649802 https://reactome.org/PathwayBrowser/#/R-DDI-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Dictyostelium discoideum 59789 R-DDI-5661117 https://reactome.org/PathwayBrowser/#/R-DDI-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Dictyostelium discoideum 59789 R-DDI-5661126 https://reactome.org/PathwayBrowser/#/R-DDI-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Dictyostelium discoideum 59789 R-DDI-5676966 https://reactome.org/PathwayBrowser/#/R-DDI-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Dictyostelium discoideum 59789 R-DDI-5682965 https://reactome.org/PathwayBrowser/#/R-DDI-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Dictyostelium discoideum 59789 R-DDI-6788650 https://reactome.org/PathwayBrowser/#/R-DDI-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Dictyostelium discoideum 59789 R-DDI-6800138 https://reactome.org/PathwayBrowser/#/R-DDI-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Dictyostelium discoideum 59789 R-DDI-6800149 https://reactome.org/PathwayBrowser/#/R-DDI-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Dictyostelium discoideum 59789 R-DDI-77090 https://reactome.org/PathwayBrowser/#/R-DDI-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Dictyostelium discoideum 59789 R-DDI-8856945 https://reactome.org/PathwayBrowser/#/R-DDI-8856945 PP2A methylation by LCMT1 IEA Dictyostelium discoideum 59789 R-DDI-8876789 https://reactome.org/PathwayBrowser/#/R-DDI-8876789 CARNMT1 methylates CARN to Anserine IEA Dictyostelium discoideum 59789 R-DDI-8879123 https://reactome.org/PathwayBrowser/#/R-DDI-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Dictyostelium discoideum 59789 R-DDI-8931974 https://reactome.org/PathwayBrowser/#/R-DDI-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Dictyostelium discoideum 59789 R-DDI-8932221 https://reactome.org/PathwayBrowser/#/R-DDI-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Dictyostelium discoideum 59789 R-DDI-8932276 https://reactome.org/PathwayBrowser/#/R-DDI-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Dictyostelium discoideum 59789 R-DDI-8932413 https://reactome.org/PathwayBrowser/#/R-DDI-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Dictyostelium discoideum 59789 R-DDI-947535 https://reactome.org/PathwayBrowser/#/R-DDI-947535 Cyclisation of GTP to precursor Z IEA Dictyostelium discoideum 59789 R-DME-212263 https://reactome.org/PathwayBrowser/#/R-DME-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Drosophila melanogaster 59789 R-DME-212269 https://reactome.org/PathwayBrowser/#/R-DME-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Drosophila melanogaster 59789 R-DME-2162186 https://reactome.org/PathwayBrowser/#/R-DME-2162186 COQ3 methylates DeMQ10H2 IEA Drosophila melanogaster 59789 R-DME-2162188 https://reactome.org/PathwayBrowser/#/R-DME-2162188 COQ5 methylates MDMQ10H2 IEA Drosophila melanogaster 59789 R-DME-2162193 https://reactome.org/PathwayBrowser/#/R-DME-2162193 COQ3 methylates DHDB IEA Drosophila melanogaster 59789 R-DME-2301205 https://reactome.org/PathwayBrowser/#/R-DME-2301205 SETD8 monomethylates histone H4 IEA Drosophila melanogaster 59789 R-DME-3222237 https://reactome.org/PathwayBrowser/#/R-DME-3222237 SMYD2 methylates TP53 IEA Drosophila melanogaster 59789 R-DME-3240295 https://reactome.org/PathwayBrowser/#/R-DME-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Drosophila melanogaster 59789 R-DME-3364026 https://reactome.org/PathwayBrowser/#/R-DME-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Drosophila melanogaster 59789 R-DME-351222 https://reactome.org/PathwayBrowser/#/R-DME-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Drosophila melanogaster 59789 R-DME-3788745 https://reactome.org/PathwayBrowser/#/R-DME-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Drosophila melanogaster 59789 R-DME-3788748 https://reactome.org/PathwayBrowser/#/R-DME-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Drosophila melanogaster 59789 R-DME-427527 https://reactome.org/PathwayBrowser/#/R-DME-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Drosophila melanogaster 59789 R-DME-5205798 https://reactome.org/PathwayBrowser/#/R-DME-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Drosophila melanogaster 59789 R-DME-5205861 https://reactome.org/PathwayBrowser/#/R-DME-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Drosophila melanogaster 59789 R-DME-5205867 https://reactome.org/PathwayBrowser/#/R-DME-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Drosophila melanogaster 59789 R-DME-5216234 https://reactome.org/PathwayBrowser/#/R-DME-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Drosophila melanogaster 59789 R-DME-5358484 https://reactome.org/PathwayBrowser/#/R-DME-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Drosophila melanogaster 59789 R-DME-5358494 https://reactome.org/PathwayBrowser/#/R-DME-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Drosophila melanogaster 59789 R-DME-5423038 https://reactome.org/PathwayBrowser/#/R-DME-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Drosophila melanogaster 59789 R-DME-5651654 https://reactome.org/PathwayBrowser/#/R-DME-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Drosophila melanogaster 59789 R-DME-5651657 https://reactome.org/PathwayBrowser/#/R-DME-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Drosophila melanogaster 59789 R-DME-5661126 https://reactome.org/PathwayBrowser/#/R-DME-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Drosophila melanogaster 59789 R-DME-5676966 https://reactome.org/PathwayBrowser/#/R-DME-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Drosophila melanogaster 59789 R-DME-5682965 https://reactome.org/PathwayBrowser/#/R-DME-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Drosophila melanogaster 59789 R-DME-6786205 https://reactome.org/PathwayBrowser/#/R-DME-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Drosophila melanogaster 59789 R-DME-6788650 https://reactome.org/PathwayBrowser/#/R-DME-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Drosophila melanogaster 59789 R-DME-6793591 https://reactome.org/PathwayBrowser/#/R-DME-6793591 LIAS synthesizes lipoyl-GCSH IEA Drosophila melanogaster 59789 R-DME-6798317 https://reactome.org/PathwayBrowser/#/R-DME-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Drosophila melanogaster 59789 R-DME-6800138 https://reactome.org/PathwayBrowser/#/R-DME-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Drosophila melanogaster 59789 R-DME-6800149 https://reactome.org/PathwayBrowser/#/R-DME-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Drosophila melanogaster 59789 R-DME-6805740 https://reactome.org/PathwayBrowser/#/R-DME-6805740 SETD8 methylates TP53 IEA Drosophila melanogaster 59789 R-DME-6805755 https://reactome.org/PathwayBrowser/#/R-DME-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Drosophila melanogaster 59789 R-DME-77090 https://reactome.org/PathwayBrowser/#/R-DME-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Drosophila melanogaster 59789 R-DME-8855062 https://reactome.org/PathwayBrowser/#/R-DME-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Drosophila melanogaster 59789 R-DME-8856945 https://reactome.org/PathwayBrowser/#/R-DME-8856945 PP2A methylation by LCMT1 IEA Drosophila melanogaster 59789 R-DME-8876789 https://reactome.org/PathwayBrowser/#/R-DME-8876789 CARNMT1 methylates CARN to Anserine IEA Drosophila melanogaster 59789 R-DME-8879123 https://reactome.org/PathwayBrowser/#/R-DME-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Drosophila melanogaster 59789 R-DME-8931974 https://reactome.org/PathwayBrowser/#/R-DME-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Drosophila melanogaster 59789 R-DME-8932243 https://reactome.org/PathwayBrowser/#/R-DME-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Drosophila melanogaster 59789 R-DME-8932275 https://reactome.org/PathwayBrowser/#/R-DME-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Drosophila melanogaster 59789 R-DME-8932413 https://reactome.org/PathwayBrowser/#/R-DME-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Drosophila melanogaster 59789 R-DME-8934735 https://reactome.org/PathwayBrowser/#/R-DME-8934735 PRMT1 arginine-methylates RUNX1 IEA Drosophila melanogaster 59789 R-DME-8936481 https://reactome.org/PathwayBrowser/#/R-DME-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Drosophila melanogaster 59789 R-DME-8936584 https://reactome.org/PathwayBrowser/#/R-DME-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Drosophila melanogaster 59789 R-DME-8936608 https://reactome.org/PathwayBrowser/#/R-DME-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Drosophila melanogaster 59789 R-DME-8936621 https://reactome.org/PathwayBrowser/#/R-DME-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Drosophila melanogaster 59789 R-DME-8937016 https://reactome.org/PathwayBrowser/#/R-DME-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Drosophila melanogaster 59789 R-DME-8937022 https://reactome.org/PathwayBrowser/#/R-DME-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Drosophila melanogaster 59789 R-DME-8937050 https://reactome.org/PathwayBrowser/#/R-DME-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Drosophila melanogaster 59789 R-DME-8937113 https://reactome.org/PathwayBrowser/#/R-DME-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Drosophila melanogaster 59789 R-DME-947535 https://reactome.org/PathwayBrowser/#/R-DME-947535 Cyclisation of GTP to precursor Z IEA Drosophila melanogaster 59789 R-DME-9632182 https://reactome.org/PathwayBrowser/#/R-DME-9632182 PRMT1 methylates ESRs IEA Drosophila melanogaster 59789 R-DME-9647977 https://reactome.org/PathwayBrowser/#/R-DME-9647977 ICMT methylates S-Farn RAS proteins IEA Drosophila melanogaster 59789 R-DRE-1483174 https://reactome.org/PathwayBrowser/#/R-DRE-1483174 PE is methylated to PC by PEMT IEA Danio rerio 59789 R-DRE-158609 https://reactome.org/PathwayBrowser/#/R-DRE-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Danio rerio 59789 R-DRE-174391 https://reactome.org/PathwayBrowser/#/R-DRE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Danio rerio 59789 R-DRE-175983 https://reactome.org/PathwayBrowser/#/R-DRE-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Danio rerio 59789 R-DRE-175987 https://reactome.org/PathwayBrowser/#/R-DRE-175987 NNMT transfers CH3 from AdoMet to PY IEA Danio rerio 59789 R-DRE-209821 https://reactome.org/PathwayBrowser/#/R-DRE-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Danio rerio 59789 R-DRE-212263 https://reactome.org/PathwayBrowser/#/R-DRE-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Danio rerio 59789 R-DRE-212269 https://reactome.org/PathwayBrowser/#/R-DRE-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Danio rerio 59789 R-DRE-2162186 https://reactome.org/PathwayBrowser/#/R-DRE-2162186 COQ3 methylates DeMQ10H2 IEA Danio rerio 59789 R-DRE-2162188 https://reactome.org/PathwayBrowser/#/R-DRE-2162188 COQ5 methylates MDMQ10H2 IEA Danio rerio 59789 R-DRE-2162193 https://reactome.org/PathwayBrowser/#/R-DRE-2162193 COQ3 methylates DHDB IEA Danio rerio 59789 R-DRE-2301205 https://reactome.org/PathwayBrowser/#/R-DRE-2301205 SETD8 monomethylates histone H4 IEA Danio rerio 59789 R-DRE-3222237 https://reactome.org/PathwayBrowser/#/R-DRE-3222237 SMYD2 methylates TP53 IEA Danio rerio 59789 R-DRE-3240295 https://reactome.org/PathwayBrowser/#/R-DRE-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Danio rerio 59789 R-DRE-351222 https://reactome.org/PathwayBrowser/#/R-DRE-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Danio rerio 59789 R-DRE-379387 https://reactome.org/PathwayBrowser/#/R-DRE-379387 COMT transfers Met to DA to form 3MT IEA Danio rerio 59789 R-DRE-379464 https://reactome.org/PathwayBrowser/#/R-DRE-379464 COMT transfers Met to DOPAC to form HVA IEA Danio rerio 59789 R-DRE-5205798 https://reactome.org/PathwayBrowser/#/R-DRE-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Danio rerio 59789 R-DRE-5205820 https://reactome.org/PathwayBrowser/#/R-DRE-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Danio rerio 59789 R-DRE-5205861 https://reactome.org/PathwayBrowser/#/R-DRE-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Danio rerio 59789 R-DRE-5216234 https://reactome.org/PathwayBrowser/#/R-DRE-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Danio rerio 59789 R-DRE-5229203 https://reactome.org/PathwayBrowser/#/R-DRE-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Danio rerio 59789 R-DRE-5358494 https://reactome.org/PathwayBrowser/#/R-DRE-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Danio rerio 59789 R-DRE-5359451 https://reactome.org/PathwayBrowser/#/R-DRE-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Danio rerio 59789 R-DRE-5423038 https://reactome.org/PathwayBrowser/#/R-DRE-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Danio rerio 59789 R-DRE-5603114 https://reactome.org/PathwayBrowser/#/R-DRE-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Danio rerio 59789 R-DRE-5651654 https://reactome.org/PathwayBrowser/#/R-DRE-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Danio rerio 59789 R-DRE-5651657 https://reactome.org/PathwayBrowser/#/R-DRE-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Danio rerio 59789 R-DRE-5661126 https://reactome.org/PathwayBrowser/#/R-DRE-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Danio rerio 59789 R-DRE-5676966 https://reactome.org/PathwayBrowser/#/R-DRE-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Danio rerio 59789 R-DRE-5696213 https://reactome.org/PathwayBrowser/#/R-DRE-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Danio rerio 59789 R-DRE-5696220 https://reactome.org/PathwayBrowser/#/R-DRE-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Danio rerio 59789 R-DRE-6788650 https://reactome.org/PathwayBrowser/#/R-DRE-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Danio rerio 59789 R-DRE-6793591 https://reactome.org/PathwayBrowser/#/R-DRE-6793591 LIAS synthesizes lipoyl-GCSH IEA Danio rerio 59789 R-DRE-6798317 https://reactome.org/PathwayBrowser/#/R-DRE-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Danio rerio 59789 R-DRE-6800138 https://reactome.org/PathwayBrowser/#/R-DRE-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Danio rerio 59789 R-DRE-6800149 https://reactome.org/PathwayBrowser/#/R-DRE-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Danio rerio 59789 R-DRE-6804383 https://reactome.org/PathwayBrowser/#/R-DRE-6804383 PRMT5 methylates TP53 IEA Danio rerio 59789 R-DRE-6805740 https://reactome.org/PathwayBrowser/#/R-DRE-6805740 SETD8 methylates TP53 IEA Danio rerio 59789 R-DRE-71286 https://reactome.org/PathwayBrowser/#/R-DRE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Danio rerio 59789 R-DRE-8855062 https://reactome.org/PathwayBrowser/#/R-DRE-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Danio rerio 59789 R-DRE-8856945 https://reactome.org/PathwayBrowser/#/R-DRE-8856945 PP2A methylation by LCMT1 IEA Danio rerio 59789 R-DRE-8865237 https://reactome.org/PathwayBrowser/#/R-DRE-8865237 SETD6 methylates RELA in the NFkB complex IEA Danio rerio 59789 R-DRE-8879123 https://reactome.org/PathwayBrowser/#/R-DRE-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Danio rerio 59789 R-DRE-8931858 https://reactome.org/PathwayBrowser/#/R-DRE-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Danio rerio 59789 R-DRE-8931974 https://reactome.org/PathwayBrowser/#/R-DRE-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Danio rerio 59789 R-DRE-8932221 https://reactome.org/PathwayBrowser/#/R-DRE-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Danio rerio 59789 R-DRE-8932243 https://reactome.org/PathwayBrowser/#/R-DRE-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Danio rerio 59789 R-DRE-8932275 https://reactome.org/PathwayBrowser/#/R-DRE-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Danio rerio 59789 R-DRE-8932413 https://reactome.org/PathwayBrowser/#/R-DRE-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Danio rerio 59789 R-DRE-8936584 https://reactome.org/PathwayBrowser/#/R-DRE-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Danio rerio 59789 R-DRE-8936608 https://reactome.org/PathwayBrowser/#/R-DRE-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Danio rerio 59789 R-DRE-8937022 https://reactome.org/PathwayBrowser/#/R-DRE-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Danio rerio 59789 R-DRE-8937113 https://reactome.org/PathwayBrowser/#/R-DRE-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Danio rerio 59789 R-DRE-8955010 https://reactome.org/PathwayBrowser/#/R-DRE-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Danio rerio 59789 R-DRE-9647977 https://reactome.org/PathwayBrowser/#/R-DRE-9647977 ICMT methylates S-Farn RAS proteins IEA Danio rerio 59789 R-DRE-9748979 https://reactome.org/PathwayBrowser/#/R-DRE-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Danio rerio 59789 R-DRE-9748983 https://reactome.org/PathwayBrowser/#/R-DRE-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Danio rerio 59789 R-DRE-9854315 https://reactome.org/PathwayBrowser/#/R-DRE-9854315 CSKMT methylates Citrate Synthase IEA Danio rerio 59789 R-GGA-1483174 https://reactome.org/PathwayBrowser/#/R-GGA-1483174 PE is methylated to PC by PEMT IEA Gallus gallus 59789 R-GGA-158609 https://reactome.org/PathwayBrowser/#/R-GGA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Gallus gallus 59789 R-GGA-174391 https://reactome.org/PathwayBrowser/#/R-GGA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Gallus gallus 59789 R-GGA-175983 https://reactome.org/PathwayBrowser/#/R-GGA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Gallus gallus 59789 R-GGA-209821 https://reactome.org/PathwayBrowser/#/R-GGA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Gallus gallus 59789 R-GGA-209903 https://reactome.org/PathwayBrowser/#/R-GGA-209903 Noradrenaline is converted to adrenaline IEA Gallus gallus 59789 R-GGA-212263 https://reactome.org/PathwayBrowser/#/R-GGA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Gallus gallus 59789 R-GGA-212269 https://reactome.org/PathwayBrowser/#/R-GGA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Gallus gallus 59789 R-GGA-2162186 https://reactome.org/PathwayBrowser/#/R-GGA-2162186 COQ3 methylates DeMQ10H2 IEA Gallus gallus 59789 R-GGA-2162188 https://reactome.org/PathwayBrowser/#/R-GGA-2162188 COQ5 methylates MDMQ10H2 IEA Gallus gallus 59789 R-GGA-2162193 https://reactome.org/PathwayBrowser/#/R-GGA-2162193 COQ3 methylates DHDB IEA Gallus gallus 59789 R-GGA-2301205 https://reactome.org/PathwayBrowser/#/R-GGA-2301205 SETD8 monomethylates histone H4 IEA Gallus gallus 59789 R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus 59789 R-GGA-3240295 https://reactome.org/PathwayBrowser/#/R-GGA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Gallus gallus 59789 R-GGA-3364026 https://reactome.org/PathwayBrowser/#/R-GGA-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Gallus gallus 59789 R-GGA-351222 https://reactome.org/PathwayBrowser/#/R-GGA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Gallus gallus 59789 R-GGA-379387 https://reactome.org/PathwayBrowser/#/R-GGA-379387 COMT transfers Met to DA to form 3MT IEA Gallus gallus 59789 R-GGA-379464 https://reactome.org/PathwayBrowser/#/R-GGA-379464 COMT transfers Met to DOPAC to form HVA IEA Gallus gallus 59789 R-GGA-5358484 https://reactome.org/PathwayBrowser/#/R-GGA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Gallus gallus 59789 R-GGA-5358494 https://reactome.org/PathwayBrowser/#/R-GGA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Gallus gallus 59789 R-GGA-5423038 https://reactome.org/PathwayBrowser/#/R-GGA-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Gallus gallus 59789 R-GGA-5603114 https://reactome.org/PathwayBrowser/#/R-GGA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Gallus gallus 59789 R-GGA-5651654 https://reactome.org/PathwayBrowser/#/R-GGA-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Gallus gallus 59789 R-GGA-5651657 https://reactome.org/PathwayBrowser/#/R-GGA-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Gallus gallus 59789 R-GGA-5676966 https://reactome.org/PathwayBrowser/#/R-GGA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Gallus gallus 59789 R-GGA-5682965 https://reactome.org/PathwayBrowser/#/R-GGA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Gallus gallus 59789 R-GGA-5696213 https://reactome.org/PathwayBrowser/#/R-GGA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Gallus gallus 59789 R-GGA-5696220 https://reactome.org/PathwayBrowser/#/R-GGA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Gallus gallus 59789 R-GGA-6786205 https://reactome.org/PathwayBrowser/#/R-GGA-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Gallus gallus 59789 R-GGA-6788650 https://reactome.org/PathwayBrowser/#/R-GGA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Gallus gallus 59789 R-GGA-6793591 https://reactome.org/PathwayBrowser/#/R-GGA-6793591 LIAS synthesizes lipoyl-GCSH IEA Gallus gallus 59789 R-GGA-71286 https://reactome.org/PathwayBrowser/#/R-GGA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Gallus gallus 59789 R-GGA-8855062 https://reactome.org/PathwayBrowser/#/R-GGA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Gallus gallus 59789 R-GGA-8865237 https://reactome.org/PathwayBrowser/#/R-GGA-8865237 SETD6 methylates RELA in the NFkB complex IEA Gallus gallus 59789 R-GGA-8876789 https://reactome.org/PathwayBrowser/#/R-GGA-8876789 CARNMT1 methylates CARN to Anserine IEA Gallus gallus 59789 R-GGA-8879123 https://reactome.org/PathwayBrowser/#/R-GGA-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Gallus gallus 59789 R-GGA-8931974 https://reactome.org/PathwayBrowser/#/R-GGA-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Gallus gallus 59789 R-GGA-8932221 https://reactome.org/PathwayBrowser/#/R-GGA-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Gallus gallus 59789 R-GGA-8932243 https://reactome.org/PathwayBrowser/#/R-GGA-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Gallus gallus 59789 R-GGA-8932275 https://reactome.org/PathwayBrowser/#/R-GGA-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Gallus gallus 59789 R-GGA-8932413 https://reactome.org/PathwayBrowser/#/R-GGA-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Gallus gallus 59789 R-GGA-8936481 https://reactome.org/PathwayBrowser/#/R-GGA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Gallus gallus 59789 R-GGA-8936584 https://reactome.org/PathwayBrowser/#/R-GGA-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Gallus gallus 59789 R-GGA-8936608 https://reactome.org/PathwayBrowser/#/R-GGA-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Gallus gallus 59789 R-GGA-8936621 https://reactome.org/PathwayBrowser/#/R-GGA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Gallus gallus 59789 R-GGA-8937016 https://reactome.org/PathwayBrowser/#/R-GGA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Gallus gallus 59789 R-GGA-8937022 https://reactome.org/PathwayBrowser/#/R-GGA-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Gallus gallus 59789 R-GGA-8937050 https://reactome.org/PathwayBrowser/#/R-GGA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Gallus gallus 59789 R-GGA-8937113 https://reactome.org/PathwayBrowser/#/R-GGA-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Gallus gallus 59789 R-GGA-8955010 https://reactome.org/PathwayBrowser/#/R-GGA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Gallus gallus 59789 R-GGA-947535 https://reactome.org/PathwayBrowser/#/R-GGA-947535 Cyclisation of GTP to precursor Z IEA Gallus gallus 59789 R-GGA-9640254 https://reactome.org/PathwayBrowser/#/R-GGA-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Gallus gallus 59789 R-GGA-9647977 https://reactome.org/PathwayBrowser/#/R-GGA-9647977 ICMT methylates S-Farn RAS proteins IEA Gallus gallus 59789 R-GGA-9748979 https://reactome.org/PathwayBrowser/#/R-GGA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Gallus gallus 59789 R-GGA-9748983 https://reactome.org/PathwayBrowser/#/R-GGA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Gallus gallus 59789 R-HSA-1214188 https://reactome.org/PathwayBrowser/#/R-HSA-1214188 PRDM9 trimethylates histone H3 IEA Homo sapiens 59789 R-HSA-1483174 https://reactome.org/PathwayBrowser/#/R-HSA-1483174 PE is methylated to PC by PEMT TAS Homo sapiens 59789 R-HSA-158609 https://reactome.org/PathwayBrowser/#/R-HSA-158609 TPMT transfers CH3 from AdoMet to 6MP TAS Homo sapiens 59789 R-HSA-174391 https://reactome.org/PathwayBrowser/#/R-HSA-174391 MAT1A multimers transfer Ado from ATP to L-Met TAS Homo sapiens 59789 R-HSA-175976 https://reactome.org/PathwayBrowser/#/R-HSA-175976 TMT transfers CH3 from AdoMet to BME TAS Homo sapiens 59789 R-HSA-175983 https://reactome.org/PathwayBrowser/#/R-HSA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ TAS Homo sapiens 59789 R-HSA-175987 https://reactome.org/PathwayBrowser/#/R-HSA-175987 NNMT transfers CH3 from AdoMet to PY TAS Homo sapiens 59789 R-HSA-175993 https://reactome.org/PathwayBrowser/#/R-HSA-175993 HNMT transfers CH3 group from AdoMet to Hist TAS Homo sapiens 59789 R-HSA-191790 https://reactome.org/PathwayBrowser/#/R-HSA-191790 Loading and methylation of Sm proteins onto SMN Complexes TAS Homo sapiens 59789 R-HSA-209821 https://reactome.org/PathwayBrowser/#/R-HSA-209821 Methylation of N-acetyl-5-HT to form melatonin TAS Homo sapiens 59789 R-HSA-209903 https://reactome.org/PathwayBrowser/#/R-HSA-209903 Noradrenaline is converted to adrenaline TAS Homo sapiens 59789 R-HSA-212263 https://reactome.org/PathwayBrowser/#/R-HSA-212263 PRC2 trimethylates histone H3 at lysine-27 TAS Homo sapiens 59789 R-HSA-212269 https://reactome.org/PathwayBrowser/#/R-HSA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 TAS Homo sapiens 59789 R-HSA-2162186 https://reactome.org/PathwayBrowser/#/R-HSA-2162186 COQ3 methylates DeMQ10H2 TAS Homo sapiens 59789 R-HSA-2162188 https://reactome.org/PathwayBrowser/#/R-HSA-2162188 COQ5 methylates MDMQ10H2 TAS Homo sapiens 59789 R-HSA-2162193 https://reactome.org/PathwayBrowser/#/R-HSA-2162193 COQ3 methylates DHDB TAS Homo sapiens 59789 R-HSA-2301205 https://reactome.org/PathwayBrowser/#/R-HSA-2301205 SETD8 monomethylates histone H4 TAS Homo sapiens 59789 R-HSA-2408536 https://reactome.org/PathwayBrowser/#/R-HSA-2408536 H2Se is methylated to MeSeH by H2Se methyltransferase IEA Homo sapiens 59789 R-HSA-2408541 https://reactome.org/PathwayBrowser/#/R-HSA-2408541 MeSeH is methylated to Me2Se by MeSeH methyltransferase IEA Homo sapiens 59789 R-HSA-2408554 https://reactome.org/PathwayBrowser/#/R-HSA-2408554 Me2Se is methylated to Me3Se+ by INMT IEA Homo sapiens 59789 R-HSA-3149518 https://reactome.org/PathwayBrowser/#/R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl TAS Homo sapiens 59789 R-HSA-3222237 https://reactome.org/PathwayBrowser/#/R-HSA-3222237 SMYD2 methylates TP53 TAS Homo sapiens 59789 R-HSA-3240295 https://reactome.org/PathwayBrowser/#/R-HSA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter TAS Homo sapiens 59789 R-HSA-3318563 https://reactome.org/PathwayBrowser/#/R-HSA-3318563 Defective MTRR does not convert cob(II)alamin to MeCbl TAS Homo sapiens 59789 R-HSA-3364026 https://reactome.org/PathwayBrowser/#/R-HSA-3364026 SET1 complex trimethylates H3K4 at the MYC gene TAS Homo sapiens 59789 R-HSA-351222 https://reactome.org/PathwayBrowser/#/R-HSA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 TAS Homo sapiens 59789 R-HSA-3788745 https://reactome.org/PathwayBrowser/#/R-HSA-3788745 EHMT1:EHMT2 methylates IL8 promoter TAS Homo sapiens 59789 R-HSA-3788748 https://reactome.org/PathwayBrowser/#/R-HSA-3788748 EHMT1:EHMT2 methylates IL6 promoter TAS Homo sapiens 59789 R-HSA-379387 https://reactome.org/PathwayBrowser/#/R-HSA-379387 COMT transfers Met to DA to form 3MT TAS Homo sapiens 59789 R-HSA-379464 https://reactome.org/PathwayBrowser/#/R-HSA-379464 COMT transfers Met to DOPAC to form HVA TAS Homo sapiens 59789 R-HSA-427336 https://reactome.org/PathwayBrowser/#/R-HSA-427336 TTF1:rRNA promoter:ERCC6:EHMT2 complex dimethylates histone H3 at lysine-9. IEA Homo sapiens 59789 R-HSA-427527 https://reactome.org/PathwayBrowser/#/R-HSA-427527 eNoSC dimethylates histone H3 at lysine-9 TAS Homo sapiens 59789 R-HSA-433672 https://reactome.org/PathwayBrowser/#/R-HSA-433672 NoRC:HDAC:DNMT deacetylates histone H4 and methylates histone H3 IEA Homo sapiens 59789 R-HSA-4827382 https://reactome.org/PathwayBrowser/#/R-HSA-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) TAS Homo sapiens 59789 R-HSA-4827383 https://reactome.org/PathwayBrowser/#/R-HSA-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) TAS Homo sapiens 59789 R-HSA-5159245 https://reactome.org/PathwayBrowser/#/R-HSA-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) TAS Homo sapiens 59789 R-HSA-5205798 https://reactome.org/PathwayBrowser/#/R-HSA-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 TAS Homo sapiens 59789 R-HSA-5205799 https://reactome.org/PathwayBrowser/#/R-HSA-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) TAS Homo sapiens 59789 R-HSA-5205820 https://reactome.org/PathwayBrowser/#/R-HSA-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) TAS Homo sapiens 59789 R-HSA-5205822 https://reactome.org/PathwayBrowser/#/R-HSA-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 TAS Homo sapiens 59789 R-HSA-5205824 https://reactome.org/PathwayBrowser/#/R-HSA-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) TAS Homo sapiens 59789 R-HSA-5205861 https://reactome.org/PathwayBrowser/#/R-HSA-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) TAS Homo sapiens 59789 R-HSA-5205867 https://reactome.org/PathwayBrowser/#/R-HSA-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) TAS Homo sapiens 59789 R-HSA-5216234 https://reactome.org/PathwayBrowser/#/R-HSA-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) TAS Homo sapiens 59789 R-HSA-5218952 https://reactome.org/PathwayBrowser/#/R-HSA-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) TAS Homo sapiens 59789 R-HSA-5227490 https://reactome.org/PathwayBrowser/#/R-HSA-5227490 NoRC:HDAC:DNMT methylates cytosine of the rRNA genes IEA Homo sapiens 59789 R-HSA-5229010 https://reactome.org/PathwayBrowser/#/R-HSA-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) TAS Homo sapiens 59789 R-HSA-5229203 https://reactome.org/PathwayBrowser/#/R-HSA-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) TAS Homo sapiens 59789 R-HSA-5244692 https://reactome.org/PathwayBrowser/#/R-HSA-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) TAS Homo sapiens 59789 R-HSA-5333608 https://reactome.org/PathwayBrowser/#/R-HSA-5333608 GSSebGalNac is reduced and methylated to MeSebGalNac IEA Homo sapiens 59789 R-HSA-5334097 https://reactome.org/PathwayBrowser/#/R-HSA-5334097 DNMT3B:DNMT3L methylates cytosine in DNA IEA Homo sapiens 59789 R-HSA-5334151 https://reactome.org/PathwayBrowser/#/R-HSA-5334151 DNMT1 methylates cytosine in hemimethylated DNA IEA Homo sapiens 59789 R-HSA-5334152 https://reactome.org/PathwayBrowser/#/R-HSA-5334152 DNMT3A:DNMT3L methylates cytosine in DNA IEA Homo sapiens 59789 R-HSA-5358484 https://reactome.org/PathwayBrowser/#/R-HSA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 TAS Homo sapiens 59789 R-HSA-5358494 https://reactome.org/PathwayBrowser/#/R-HSA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 TAS Homo sapiens 59789 R-HSA-5359451 https://reactome.org/PathwayBrowser/#/R-HSA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA TAS Homo sapiens 59789 R-HSA-5423038 https://reactome.org/PathwayBrowser/#/R-HSA-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) TAS Homo sapiens 59789 R-HSA-5578717 https://reactome.org/PathwayBrowser/#/R-HSA-5578717 BCDIN3D dimethylates 5' phosphate of pre-miR-145 TAS Homo sapiens 59789 R-HSA-5603114 https://reactome.org/PathwayBrowser/#/R-HSA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met TAS Homo sapiens 59789 R-HSA-5603379 https://reactome.org/PathwayBrowser/#/R-HSA-5603379 TPMT does not transfer CH3 from AdoMet to 6MP TAS Homo sapiens 59789 R-HSA-5629203 https://reactome.org/PathwayBrowser/#/R-HSA-5629203 HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-PIWIL1:piRNA:TDRD6:TDRKH IEA Homo sapiens 59789 R-HSA-5629218 https://reactome.org/PathwayBrowser/#/R-HSA-5629218 HENMT1 methylates 2' hydroxyl at 3' end of piRNA in 6xMeR-PIWIL2:piRNA:TDRD1:TDRD12:DDX4:ASZ:MOV10L1 IEA Homo sapiens 59789 R-HSA-5629237 https://reactome.org/PathwayBrowser/#/R-HSA-5629237 HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH IEA Homo sapiens 59789 R-HSA-5634729 https://reactome.org/PathwayBrowser/#/R-HSA-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) TAS Homo sapiens 59789 R-HSA-5634750 https://reactome.org/PathwayBrowser/#/R-HSA-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) TAS Homo sapiens 59789 R-HSA-5634802 https://reactome.org/PathwayBrowser/#/R-HSA-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) TAS Homo sapiens 59789 R-HSA-5637686 https://reactome.org/PathwayBrowser/#/R-HSA-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) TAS Homo sapiens 59789 R-HSA-5638141 https://reactome.org/PathwayBrowser/#/R-HSA-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) TAS Homo sapiens 59789 R-HSA-5638157 https://reactome.org/PathwayBrowser/#/R-HSA-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) TAS Homo sapiens 59789 R-HSA-5638332 https://reactome.org/PathwayBrowser/#/R-HSA-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) TAS Homo sapiens 59789 R-HSA-5638333 https://reactome.org/PathwayBrowser/#/R-HSA-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) TAS Homo sapiens 59789 R-HSA-5649764 https://reactome.org/PathwayBrowser/#/R-HSA-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) TAS Homo sapiens 59789 R-HSA-5649799 https://reactome.org/PathwayBrowser/#/R-HSA-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) TAS Homo sapiens 59789 R-HSA-5649800 https://reactome.org/PathwayBrowser/#/R-HSA-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) TAS Homo sapiens 59789 R-HSA-5649801 https://reactome.org/PathwayBrowser/#/R-HSA-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) TAS Homo sapiens 59789 R-HSA-5649802 https://reactome.org/PathwayBrowser/#/R-HSA-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) TAS Homo sapiens 59789 R-HSA-5651654 https://reactome.org/PathwayBrowser/#/R-HSA-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) TAS Homo sapiens 59789 R-HSA-5651657 https://reactome.org/PathwayBrowser/#/R-HSA-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) TAS Homo sapiens 59789 R-HSA-5661117 https://reactome.org/PathwayBrowser/#/R-HSA-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 TAS Homo sapiens 59789 R-HSA-5661126 https://reactome.org/PathwayBrowser/#/R-HSA-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 TAS Homo sapiens 59789 R-HSA-5676966 https://reactome.org/PathwayBrowser/#/R-HSA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp TAS Homo sapiens 59789 R-HSA-5682965 https://reactome.org/PathwayBrowser/#/R-HSA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs TAS Homo sapiens 59789 R-HSA-5696213 https://reactome.org/PathwayBrowser/#/R-HSA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite TAS Homo sapiens 59789 R-HSA-5696220 https://reactome.org/PathwayBrowser/#/R-HSA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) TAS Homo sapiens 59789 R-HSA-6782286 https://reactome.org/PathwayBrowser/#/R-HSA-6782286 METTL1:WDR4 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 IEA Homo sapiens 59789 R-HSA-6782388 https://reactome.org/PathwayBrowser/#/R-HSA-6782388 NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) IEA Homo sapiens 59789 R-HSA-6782416 https://reactome.org/PathwayBrowser/#/R-HSA-6782416 TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) TAS Homo sapiens 59789 R-HSA-6782419 https://reactome.org/PathwayBrowser/#/R-HSA-6782419 TRDMT1 (DNMT2) methylates cytidine-38 of tRNA(Asp) TAS Homo sapiens 59789 R-HSA-6782859 https://reactome.org/PathwayBrowser/#/R-HSA-6782859 TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 59789 R-HSA-6782879 https://reactome.org/PathwayBrowser/#/R-HSA-6782879 TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 59789 R-HSA-6782881 https://reactome.org/PathwayBrowser/#/R-HSA-6782881 LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 59789 R-HSA-6782890 https://reactome.org/PathwayBrowser/#/R-HSA-6782890 LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 59789 R-HSA-6782893 https://reactome.org/PathwayBrowser/#/R-HSA-6782893 TRMT12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 59789 R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 59789 R-HSA-6783473 https://reactome.org/PathwayBrowser/#/R-HSA-6783473 LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 59789 R-HSA-6783492 https://reactome.org/PathwayBrowser/#/R-HSA-6783492 TRMT6:TRMT61A methylate adenosine yielding 1-methyladenosine at nucleotide 58 of tRNA(Met) TAS Homo sapiens 59789 R-HSA-6785409 https://reactome.org/PathwayBrowser/#/R-HSA-6785409 NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) IEA Homo sapiens 59789 R-HSA-6785438 https://reactome.org/PathwayBrowser/#/R-HSA-6785438 NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) TAS Homo sapiens 59789 R-HSA-6786205 https://reactome.org/PathwayBrowser/#/R-HSA-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 TAS Homo sapiens 59789 R-HSA-6786500 https://reactome.org/PathwayBrowser/#/R-HSA-6786500 ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 IEA Homo sapiens 59789 R-HSA-6786501 https://reactome.org/PathwayBrowser/#/R-HSA-6786501 TRMT11:TRMT112 methylates guanosine-10 in tRNA IEA Homo sapiens 59789 R-HSA-6786567 https://reactome.org/PathwayBrowser/#/R-HSA-6786567 KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine TAS Homo sapiens 59789 R-HSA-6786571 https://reactome.org/PathwayBrowser/#/R-HSA-6786571 CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37 TAS Homo sapiens 59789 R-HSA-6786621 https://reactome.org/PathwayBrowser/#/R-HSA-6786621 TRMT10A methylates guanosine-9 in tRNA IEA Homo sapiens 59789 R-HSA-6787525 https://reactome.org/PathwayBrowser/#/R-HSA-6787525 TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58 TAS Homo sapiens 59789 R-HSA-6787591 https://reactome.org/PathwayBrowser/#/R-HSA-6787591 TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9 TAS Homo sapiens 59789 R-HSA-6787594 https://reactome.org/PathwayBrowser/#/R-HSA-6787594 TRMT10C:HSD17B10 (TRMT10C:SDR5C1) methylates adenosine-9 in tRNA yielding 1-methyladenosine-9 TAS Homo sapiens 59789 R-HSA-6788650 https://reactome.org/PathwayBrowser/#/R-HSA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins TAS Homo sapiens 59789 R-HSA-6788668 https://reactome.org/PathwayBrowser/#/R-HSA-6788668 TRMT13 2'-O-methylates adenosine-4 in tRNA IEA Homo sapiens 59789 R-HSA-6788684 https://reactome.org/PathwayBrowser/#/R-HSA-6788684 TRMT13 2'-O-methylates cytidine-4 in tRNA IEA Homo sapiens 59789 R-HSA-6788707 https://reactome.org/PathwayBrowser/#/R-HSA-6788707 TRMT44 2'-O-methylates uridine-44 in tRNA(Ser) IEA Homo sapiens 59789 R-HSA-6790906 https://reactome.org/PathwayBrowser/#/R-HSA-6790906 EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 IEA Homo sapiens 59789 R-HSA-6790907 https://reactome.org/PathwayBrowser/#/R-HSA-6790907 Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides IEA Homo sapiens 59789 R-HSA-6790944 https://reactome.org/PathwayBrowser/#/R-HSA-6790944 NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447 IEA Homo sapiens 59789 R-HSA-6790982 https://reactome.org/PathwayBrowser/#/R-HSA-6790982 WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639 TAS Homo sapiens 59789 R-HSA-6790994 https://reactome.org/PathwayBrowser/#/R-HSA-6790994 DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851 TAS Homo sapiens 59789 R-HSA-6793057 https://reactome.org/PathwayBrowser/#/R-HSA-6793057 NSUN4 methylates cytidine-841 of 12S rRNA yielding 5-methylcytidine-841 TAS Homo sapiens 59789 R-HSA-6793066 https://reactome.org/PathwayBrowser/#/R-HSA-6793066 TFB1M dimethylates adenosine-936 and adenosine-937 of 12S rRNA yielding 6-dimethyladenosine-936 and 6-dimethyladenosine-937 TAS Homo sapiens 59789 R-HSA-6793096 https://reactome.org/PathwayBrowser/#/R-HSA-6793096 MRM3 (RNMTL1) methylates guanosine-1370 of 16S rRNA yielding 2'-O-methylguanosine-1370 TAS Homo sapiens 59789 R-HSA-6793122 https://reactome.org/PathwayBrowser/#/R-HSA-6793122 MRM1 methylates guanosine-1145 of 16S rRNA yielding 2'-O-methylguanosine-1145 TAS Homo sapiens 59789 R-HSA-6793127 https://reactome.org/PathwayBrowser/#/R-HSA-6793127 MRM2 (FTSJ2) methylates uridine-1369 of 16S rRNA yielding 2'-O-methyluridine TAS Homo sapiens 59789 R-HSA-6793591 https://reactome.org/PathwayBrowser/#/R-HSA-6793591 LIAS synthesizes lipoyl-GCSH TAS Homo sapiens 59789 R-HSA-6798317 https://reactome.org/PathwayBrowser/#/R-HSA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC TAS Homo sapiens 59789 R-HSA-6800138 https://reactome.org/PathwayBrowser/#/R-HSA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer TAS Homo sapiens 59789 R-HSA-6800149 https://reactome.org/PathwayBrowser/#/R-HSA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII TAS Homo sapiens 59789 R-HSA-6804383 https://reactome.org/PathwayBrowser/#/R-HSA-6804383 PRMT5 methylates TP53 TAS Homo sapiens 59789 R-HSA-6805730 https://reactome.org/PathwayBrowser/#/R-HSA-6805730 SETD9 methylates TP53 TAS Homo sapiens 59789 R-HSA-6805740 https://reactome.org/PathwayBrowser/#/R-HSA-6805740 SETD8 methylates TP53 TAS Homo sapiens 59789 R-HSA-6805755 https://reactome.org/PathwayBrowser/#/R-HSA-6805755 EHMT1:EHMT2 dimethylates TP53 TAS Homo sapiens 59789 R-HSA-71286 https://reactome.org/PathwayBrowser/#/R-HSA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine TAS Homo sapiens 59789 R-HSA-77090 https://reactome.org/PathwayBrowser/#/R-HSA-77090 Methylation of GMP-cap by RNA Methyltransferase TAS Homo sapiens 59789 R-HSA-8855062 https://reactome.org/PathwayBrowser/#/R-HSA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy TAS Homo sapiens 59789 R-HSA-8856945 https://reactome.org/PathwayBrowser/#/R-HSA-8856945 PP2A methylation by LCMT1 TAS Homo sapiens 59789 R-HSA-8865237 https://reactome.org/PathwayBrowser/#/R-HSA-8865237 SETD6 methylates RELA in the NFkB complex TAS Homo sapiens 59789 R-HSA-8865498 https://reactome.org/PathwayBrowser/#/R-HSA-8865498 KMT2A trimethylates nucleosomes at the SPI1 gene locus producing H3K4Me3 mark IEA Homo sapiens 59789 R-HSA-8868783 https://reactome.org/PathwayBrowser/#/R-HSA-8868783 TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248 TAS Homo sapiens 59789 R-HSA-8876789 https://reactome.org/PathwayBrowser/#/R-HSA-8876789 CARNMT1 methylates CARN to Anserine TAS Homo sapiens 59789 R-HSA-8879123 https://reactome.org/PathwayBrowser/#/R-HSA-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 TAS Homo sapiens 59789 R-HSA-8931858 https://reactome.org/PathwayBrowser/#/R-HSA-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB TAS Homo sapiens 59789 R-HSA-8931974 https://reactome.org/PathwayBrowser/#/R-HSA-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A TAS Homo sapiens 59789 R-HSA-8932221 https://reactome.org/PathwayBrowser/#/R-HSA-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 TAS Homo sapiens 59789 R-HSA-8932243 https://reactome.org/PathwayBrowser/#/R-HSA-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 TAS Homo sapiens 59789 R-HSA-8932275 https://reactome.org/PathwayBrowser/#/R-HSA-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN TAS Homo sapiens 59789 R-HSA-8932276 https://reactome.org/PathwayBrowser/#/R-HSA-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP TAS Homo sapiens 59789 R-HSA-8932413 https://reactome.org/PathwayBrowser/#/R-HSA-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 TAS Homo sapiens 59789 R-HSA-8932765 https://reactome.org/PathwayBrowser/#/R-HSA-8932765 NSUN6 methylates cytidine-72 in tRNA(Cys) and tRNA(Thr) TAS Homo sapiens 59789 R-HSA-8934735 https://reactome.org/PathwayBrowser/#/R-HSA-8934735 PRMT1 arginine-methylates RUNX1 TAS Homo sapiens 59789 R-HSA-8936481 https://reactome.org/PathwayBrowser/#/R-HSA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter TAS Homo sapiens 59789 R-HSA-8936584 https://reactome.org/PathwayBrowser/#/R-HSA-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter TAS Homo sapiens 59789 R-HSA-8936608 https://reactome.org/PathwayBrowser/#/R-HSA-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter TAS Homo sapiens 59789 R-HSA-8936621 https://reactome.org/PathwayBrowser/#/R-HSA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter TAS Homo sapiens 59789 R-HSA-8937016 https://reactome.org/PathwayBrowser/#/R-HSA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter TAS Homo sapiens 59789 R-HSA-8937022 https://reactome.org/PathwayBrowser/#/R-HSA-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter TAS Homo sapiens 59789 R-HSA-8937050 https://reactome.org/PathwayBrowser/#/R-HSA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter TAS Homo sapiens 59789 R-HSA-8937113 https://reactome.org/PathwayBrowser/#/R-HSA-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter TAS Homo sapiens 59789 R-HSA-8955010 https://reactome.org/PathwayBrowser/#/R-HSA-8955010 LRTOMT transfers Met to DA, forming 3MT TAS Homo sapiens 59789 R-HSA-9024159 https://reactome.org/PathwayBrowser/#/R-HSA-9024159 FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe) TAS Homo sapiens 59789 R-HSA-9024161 https://reactome.org/PathwayBrowser/#/R-HSA-9024161 FTSJ1 2'-O-methylates guanosine-34 in tRNA(Phe) TAS Homo sapiens 59789 R-HSA-947535 https://reactome.org/PathwayBrowser/#/R-HSA-947535 Cyclisation of GTP to precursor Z TAS Homo sapiens 59789 R-HSA-9632182 https://reactome.org/PathwayBrowser/#/R-HSA-9632182 PRMT1 methylates ESRs TAS Homo sapiens 59789 R-HSA-9640254 https://reactome.org/PathwayBrowser/#/R-HSA-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 TAS Homo sapiens 59789 R-HSA-9647977 https://reactome.org/PathwayBrowser/#/R-HSA-9647977 ICMT methylates S-Farn RAS proteins TAS Homo sapiens 59789 R-HSA-9684016 https://reactome.org/PathwayBrowser/#/R-HSA-9684016 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 59789 R-HSA-9684017 https://reactome.org/PathwayBrowser/#/R-HSA-9684017 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 59789 R-HSA-9684018 https://reactome.org/PathwayBrowser/#/R-HSA-9684018 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 59789 R-HSA-9684030 https://reactome.org/PathwayBrowser/#/R-HSA-9684030 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 59789 R-HSA-9684032 https://reactome.org/PathwayBrowser/#/R-HSA-9684032 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 59789 R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 59789 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 59789 R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 59789 R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 59789 R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 59789 R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 59789 R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 59789 R-HSA-9710490 https://reactome.org/PathwayBrowser/#/R-HSA-9710490 The GSDME gene promoter is hypermethylated TAS Homo sapiens 59789 R-HSA-9729283 https://reactome.org/PathwayBrowser/#/R-HSA-9729283 Nucleoprotein is methylated by PRMT1 TAS Homo sapiens 59789 R-HSA-9748979 https://reactome.org/PathwayBrowser/#/R-HSA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP TAS Homo sapiens 59789 R-HSA-9748983 https://reactome.org/PathwayBrowser/#/R-HSA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP TAS Homo sapiens 59789 R-HSA-9822583 https://reactome.org/PathwayBrowser/#/R-HSA-9822583 METTL23 dimethylates histone H3.3 arginine-17 (arginine-18 in the preprotein) IEA Homo sapiens 59789 R-HSA-9830848 https://reactome.org/PathwayBrowser/#/R-HSA-9830848 L protein acts as a cap N7 methyltransferase to modify RSV mRNAs TAS Homo sapiens 59789 R-HSA-9834003 https://reactome.org/PathwayBrowser/#/R-HSA-9834003 L protein acts as a cap 2'-O-methyltransferase to modify RSV mRNAs TAS Homo sapiens 59789 R-HSA-9854315 https://reactome.org/PathwayBrowser/#/R-HSA-9854315 CSKMT methylates Citrate Synthase TAS Homo sapiens 59789 R-MMU-1214198 https://reactome.org/PathwayBrowser/#/R-MMU-1214198 Prdm9 Trimethylates Histone H3 at Lysine-4 TAS Mus musculus 59789 R-MMU-1483174 https://reactome.org/PathwayBrowser/#/R-MMU-1483174 PE is methylated to PC by PEMT IEA Mus musculus 59789 R-MMU-158609 https://reactome.org/PathwayBrowser/#/R-MMU-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Mus musculus 59789 R-MMU-174391 https://reactome.org/PathwayBrowser/#/R-MMU-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Mus musculus 59789 R-MMU-175983 https://reactome.org/PathwayBrowser/#/R-MMU-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Mus musculus 59789 R-MMU-175987 https://reactome.org/PathwayBrowser/#/R-MMU-175987 NNMT transfers CH3 from AdoMet to PY IEA Mus musculus 59789 R-MMU-191790 https://reactome.org/PathwayBrowser/#/R-MMU-191790 Loading and methylation of Sm proteins onto SMN Complexes IEA Mus musculus 59789 R-MMU-209821 https://reactome.org/PathwayBrowser/#/R-MMU-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Mus musculus 59789 R-MMU-209903 https://reactome.org/PathwayBrowser/#/R-MMU-209903 Noradrenaline is converted to adrenaline IEA Mus musculus 59789 R-MMU-212263 https://reactome.org/PathwayBrowser/#/R-MMU-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Mus musculus 59789 R-MMU-212269 https://reactome.org/PathwayBrowser/#/R-MMU-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Mus musculus 59789 R-MMU-2162186 https://reactome.org/PathwayBrowser/#/R-MMU-2162186 COQ3 methylates DeMQ10H2 IEA Mus musculus 59789 R-MMU-2162188 https://reactome.org/PathwayBrowser/#/R-MMU-2162188 COQ5 methylates MDMQ10H2 IEA Mus musculus 59789 R-MMU-2162193 https://reactome.org/PathwayBrowser/#/R-MMU-2162193 COQ3 methylates DHDB IEA Mus musculus 59789 R-MMU-2408549 https://reactome.org/PathwayBrowser/#/R-MMU-2408549 Me2Se is methylated to Me3Se+ by Inmt TAS Mus musculus 59789 R-MMU-3149518 https://reactome.org/PathwayBrowser/#/R-MMU-3149518 MTRR reduces cob(II)alamin to meCbl IEA Mus musculus 59789 R-MMU-3222237 https://reactome.org/PathwayBrowser/#/R-MMU-3222237 SMYD2 methylates TP53 IEA Mus musculus 59789 R-MMU-351222 https://reactome.org/PathwayBrowser/#/R-MMU-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Mus musculus 59789 R-MMU-379387 https://reactome.org/PathwayBrowser/#/R-MMU-379387 COMT transfers Met to DA to form 3MT IEA Mus musculus 59789 R-MMU-379464 https://reactome.org/PathwayBrowser/#/R-MMU-379464 COMT transfers Met to DOPAC to form HVA IEA Mus musculus 59789 R-MMU-4827382 https://reactome.org/PathwayBrowser/#/R-MMU-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Mus musculus 59789 R-MMU-4827383 https://reactome.org/PathwayBrowser/#/R-MMU-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Mus musculus 59789 R-MMU-5159245 https://reactome.org/PathwayBrowser/#/R-MMU-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Mus musculus 59789 R-MMU-5205798 https://reactome.org/PathwayBrowser/#/R-MMU-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Mus musculus 59789 R-MMU-5205799 https://reactome.org/PathwayBrowser/#/R-MMU-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Mus musculus 59789 R-MMU-5205820 https://reactome.org/PathwayBrowser/#/R-MMU-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Mus musculus 59789 R-MMU-5205822 https://reactome.org/PathwayBrowser/#/R-MMU-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 IEA Mus musculus 59789 R-MMU-5205824 https://reactome.org/PathwayBrowser/#/R-MMU-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Mus musculus 59789 R-MMU-5205861 https://reactome.org/PathwayBrowser/#/R-MMU-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Mus musculus 59789 R-MMU-5205867 https://reactome.org/PathwayBrowser/#/R-MMU-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Mus musculus 59789 R-MMU-5218952 https://reactome.org/PathwayBrowser/#/R-MMU-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Mus musculus 59789 R-MMU-5229010 https://reactome.org/PathwayBrowser/#/R-MMU-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) IEA Mus musculus 59789 R-MMU-5229203 https://reactome.org/PathwayBrowser/#/R-MMU-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Mus musculus 59789 R-MMU-5244692 https://reactome.org/PathwayBrowser/#/R-MMU-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Mus musculus 59789 R-MMU-5336316 https://reactome.org/PathwayBrowser/#/R-MMU-5336316 Dnmt3a:Dnmt3l methylates cytosine in DNA TAS Mus musculus 59789 R-MMU-5336369 https://reactome.org/PathwayBrowser/#/R-MMU-5336369 Dnmt1 methylates cytosine in hemimethylated DNA TAS Mus musculus 59789 R-MMU-5336380 https://reactome.org/PathwayBrowser/#/R-MMU-5336380 Dnmt3b:Dnmt3l methylates cytosine in DNA TAS Mus musculus 59789 R-MMU-5358484 https://reactome.org/PathwayBrowser/#/R-MMU-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Mus musculus 59789 R-MMU-5358494 https://reactome.org/PathwayBrowser/#/R-MMU-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Mus musculus 59789 R-MMU-5359451 https://reactome.org/PathwayBrowser/#/R-MMU-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Mus musculus 59789 R-MMU-5423038 https://reactome.org/PathwayBrowser/#/R-MMU-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Mus musculus 59789 R-MMU-5603114 https://reactome.org/PathwayBrowser/#/R-MMU-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Mus musculus 59789 R-MMU-5629217 https://reactome.org/PathwayBrowser/#/R-MMU-5629217 Henmt1 methylates 2' hydroxyl at 3' end of piRNA in Asz1:Ddx4:Mov10l1:6xMeR-Piwil2:piRNA:Tdrd1:Tdrd12 TAS Mus musculus 59789 R-MMU-5629230 https://reactome.org/PathwayBrowser/#/R-MMU-5629230 Henmt1 methylates 2' hydroxyl at 3' end of piRNA in MeR-Piwil4:piRNA:Tdrd9:Mael:Tdrkh TAS Mus musculus 59789 R-MMU-5629239 https://reactome.org/PathwayBrowser/#/R-MMU-5629239 Henmt1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-Piwil1:piRNA:Tdrd6:Tdrkh TAS Mus musculus 59789 R-MMU-5634729 https://reactome.org/PathwayBrowser/#/R-MMU-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Mus musculus 59789 R-MMU-5634750 https://reactome.org/PathwayBrowser/#/R-MMU-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Mus musculus 59789 R-MMU-5634802 https://reactome.org/PathwayBrowser/#/R-MMU-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Mus musculus 59789 R-MMU-5637686 https://reactome.org/PathwayBrowser/#/R-MMU-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Mus musculus 59789 R-MMU-5638141 https://reactome.org/PathwayBrowser/#/R-MMU-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) IEA Mus musculus 59789 R-MMU-5638157 https://reactome.org/PathwayBrowser/#/R-MMU-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Mus musculus 59789 R-MMU-5638332 https://reactome.org/PathwayBrowser/#/R-MMU-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Mus musculus 59789 R-MMU-5638333 https://reactome.org/PathwayBrowser/#/R-MMU-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Mus musculus 59789 R-MMU-5649764 https://reactome.org/PathwayBrowser/#/R-MMU-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Mus musculus 59789 R-MMU-5649799 https://reactome.org/PathwayBrowser/#/R-MMU-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Mus musculus 59789 R-MMU-5649800 https://reactome.org/PathwayBrowser/#/R-MMU-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Mus musculus 59789 R-MMU-5649801 https://reactome.org/PathwayBrowser/#/R-MMU-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Mus musculus 59789 R-MMU-5649802 https://reactome.org/PathwayBrowser/#/R-MMU-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Mus musculus 59789 R-MMU-5651654 https://reactome.org/PathwayBrowser/#/R-MMU-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Mus musculus 59789 R-MMU-5651657 https://reactome.org/PathwayBrowser/#/R-MMU-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Mus musculus 59789 R-MMU-5661117 https://reactome.org/PathwayBrowser/#/R-MMU-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Mus musculus 59789 R-MMU-5661126 https://reactome.org/PathwayBrowser/#/R-MMU-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Mus musculus 59789 R-MMU-5676966 https://reactome.org/PathwayBrowser/#/R-MMU-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Mus musculus 59789 R-MMU-5682965 https://reactome.org/PathwayBrowser/#/R-MMU-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Mus musculus 59789 R-MMU-5696213 https://reactome.org/PathwayBrowser/#/R-MMU-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Mus musculus 59789 R-MMU-5696220 https://reactome.org/PathwayBrowser/#/R-MMU-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Mus musculus 59789 R-MMU-573376 https://reactome.org/PathwayBrowser/#/R-MMU-573376 NoRC:intergenic spacer:Hdac:Dnmt complex deacetylates histone H4 and dimethylates lysine-9 of histone H3 in main promoter of the rRNA gene TAS Mus musculus 59789 R-MMU-573383 https://reactome.org/PathwayBrowser/#/R-MMU-573383 NoRC:intergenic spacer:Hdac:Dnmt complex methylates cytosine in the rRNA genes TAS Mus musculus 59789 R-MMU-6786205 https://reactome.org/PathwayBrowser/#/R-MMU-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Mus musculus 59789 R-MMU-6788650 https://reactome.org/PathwayBrowser/#/R-MMU-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Mus musculus 59789 R-MMU-6793591 https://reactome.org/PathwayBrowser/#/R-MMU-6793591 LIAS synthesizes lipoyl-GCSH IEA Mus musculus 59789 R-MMU-6798317 https://reactome.org/PathwayBrowser/#/R-MMU-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Mus musculus 59789 R-MMU-6800138 https://reactome.org/PathwayBrowser/#/R-MMU-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Mus musculus 59789 R-MMU-6800149 https://reactome.org/PathwayBrowser/#/R-MMU-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Mus musculus 59789 R-MMU-6804383 https://reactome.org/PathwayBrowser/#/R-MMU-6804383 PRMT5 methylates TP53 IEA Mus musculus 59789 R-MMU-6805740 https://reactome.org/PathwayBrowser/#/R-MMU-6805740 SETD8 methylates TP53 IEA Mus musculus 59789 R-MMU-6805755 https://reactome.org/PathwayBrowser/#/R-MMU-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Mus musculus 59789 R-MMU-71286 https://reactome.org/PathwayBrowser/#/R-MMU-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Mus musculus 59789 R-MMU-77090 https://reactome.org/PathwayBrowser/#/R-MMU-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Mus musculus 59789 R-MMU-8855062 https://reactome.org/PathwayBrowser/#/R-MMU-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Mus musculus 59789 R-MMU-8856945 https://reactome.org/PathwayBrowser/#/R-MMU-8856945 PP2A methylation by LCMT1 IEA Mus musculus 59789 R-MMU-8865237 https://reactome.org/PathwayBrowser/#/R-MMU-8865237 SETD6 methylates RELA in the NFkB complex IEA Mus musculus 59789 R-MMU-8876789 https://reactome.org/PathwayBrowser/#/R-MMU-8876789 CARNMT1 methylates CARN to Anserine IEA Mus musculus 59789 R-MMU-8879123 https://reactome.org/PathwayBrowser/#/R-MMU-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Mus musculus 59789 R-MMU-8931858 https://reactome.org/PathwayBrowser/#/R-MMU-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Mus musculus 59789 R-MMU-8931974 https://reactome.org/PathwayBrowser/#/R-MMU-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Mus musculus 59789 R-MMU-8932221 https://reactome.org/PathwayBrowser/#/R-MMU-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Mus musculus 59789 R-MMU-8932243 https://reactome.org/PathwayBrowser/#/R-MMU-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Mus musculus 59789 R-MMU-8932275 https://reactome.org/PathwayBrowser/#/R-MMU-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Mus musculus 59789 R-MMU-8932276 https://reactome.org/PathwayBrowser/#/R-MMU-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Mus musculus 59789 R-MMU-8932413 https://reactome.org/PathwayBrowser/#/R-MMU-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Mus musculus 59789 R-MMU-8934735 https://reactome.org/PathwayBrowser/#/R-MMU-8934735 PRMT1 arginine-methylates RUNX1 IEA Mus musculus 59789 R-MMU-8936481 https://reactome.org/PathwayBrowser/#/R-MMU-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Mus musculus 59789 R-MMU-8936584 https://reactome.org/PathwayBrowser/#/R-MMU-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Mus musculus 59789 R-MMU-8936608 https://reactome.org/PathwayBrowser/#/R-MMU-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Mus musculus 59789 R-MMU-8936621 https://reactome.org/PathwayBrowser/#/R-MMU-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Mus musculus 59789 R-MMU-8937016 https://reactome.org/PathwayBrowser/#/R-MMU-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Mus musculus 59789 R-MMU-8937022 https://reactome.org/PathwayBrowser/#/R-MMU-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Mus musculus 59789 R-MMU-8937050 https://reactome.org/PathwayBrowser/#/R-MMU-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Mus musculus 59789 R-MMU-8937113 https://reactome.org/PathwayBrowser/#/R-MMU-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Mus musculus 59789 R-MMU-8955010 https://reactome.org/PathwayBrowser/#/R-MMU-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Mus musculus 59789 R-MMU-947535 https://reactome.org/PathwayBrowser/#/R-MMU-947535 Cyclisation of GTP to precursor Z IEA Mus musculus 59789 R-MMU-9632182 https://reactome.org/PathwayBrowser/#/R-MMU-9632182 PRMT1 methylates ESRs IEA Mus musculus 59789 R-MMU-9640254 https://reactome.org/PathwayBrowser/#/R-MMU-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Mus musculus 59789 R-MMU-9647977 https://reactome.org/PathwayBrowser/#/R-MMU-9647977 ICMT methylates S-Farn RAS proteins IEA Mus musculus 59789 R-MMU-9748979 https://reactome.org/PathwayBrowser/#/R-MMU-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Mus musculus 59789 R-MMU-9748983 https://reactome.org/PathwayBrowser/#/R-MMU-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Mus musculus 59789 R-MMU-9822592 https://reactome.org/PathwayBrowser/#/R-MMU-9822592 Mettl23 dimethylates histone H3.3 arginine-18 (arginine-17 in the mature protein) TAS Mus musculus 59789 R-NUL-1214205 https://reactome.org/PathwayBrowser/#/R-NUL-1214205 Prdm9 Trimethylates Histone H3 (murine, bovine) TAS Bos taurus 59789 R-NUL-573373 https://reactome.org/PathwayBrowser/#/R-NUL-573373 Ttf-I:rRNA Promoter:Ercc6:Ehmt2 complex dimethylates histone H3 at lysine-9 TAS Homo sapiens 59789 R-NUL-8865525 https://reactome.org/PathwayBrowser/#/R-NUL-8865525 KTM2A trimethylates nucleosomes at the Spi1 gene locus producing H3K4Me3 mark TAS Homo sapiens 59789 R-PFA-174391 https://reactome.org/PathwayBrowser/#/R-PFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Plasmodium falciparum 59789 R-PFA-2301205 https://reactome.org/PathwayBrowser/#/R-PFA-2301205 SETD8 monomethylates histone H4 IEA Plasmodium falciparum 59789 R-PFA-4827383 https://reactome.org/PathwayBrowser/#/R-PFA-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Plasmodium falciparum 59789 R-PFA-5159245 https://reactome.org/PathwayBrowser/#/R-PFA-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Plasmodium falciparum 59789 R-PFA-5205798 https://reactome.org/PathwayBrowser/#/R-PFA-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Plasmodium falciparum 59789 R-PFA-5205867 https://reactome.org/PathwayBrowser/#/R-PFA-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Plasmodium falciparum 59789 R-PFA-5218952 https://reactome.org/PathwayBrowser/#/R-PFA-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Plasmodium falciparum 59789 R-PFA-5244692 https://reactome.org/PathwayBrowser/#/R-PFA-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Plasmodium falciparum 59789 R-PFA-5358484 https://reactome.org/PathwayBrowser/#/R-PFA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Plasmodium falciparum 59789 R-PFA-5358494 https://reactome.org/PathwayBrowser/#/R-PFA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Plasmodium falciparum 59789 R-PFA-5423038 https://reactome.org/PathwayBrowser/#/R-PFA-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Plasmodium falciparum 59789 R-PFA-5637686 https://reactome.org/PathwayBrowser/#/R-PFA-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Plasmodium falciparum 59789 R-PFA-5638157 https://reactome.org/PathwayBrowser/#/R-PFA-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Plasmodium falciparum 59789 R-PFA-5638333 https://reactome.org/PathwayBrowser/#/R-PFA-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Plasmodium falciparum 59789 R-PFA-5649800 https://reactome.org/PathwayBrowser/#/R-PFA-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Plasmodium falciparum 59789 R-PFA-5649802 https://reactome.org/PathwayBrowser/#/R-PFA-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Plasmodium falciparum 59789 R-PFA-5661126 https://reactome.org/PathwayBrowser/#/R-PFA-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Plasmodium falciparum 59789 R-PFA-5676966 https://reactome.org/PathwayBrowser/#/R-PFA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Plasmodium falciparum 59789 R-PFA-6788650 https://reactome.org/PathwayBrowser/#/R-PFA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Plasmodium falciparum 59789 R-PFA-6800138 https://reactome.org/PathwayBrowser/#/R-PFA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Plasmodium falciparum 59789 R-PFA-6800149 https://reactome.org/PathwayBrowser/#/R-PFA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Plasmodium falciparum 59789 R-PFA-8855062 https://reactome.org/PathwayBrowser/#/R-PFA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Plasmodium falciparum 59789 R-PFA-8876789 https://reactome.org/PathwayBrowser/#/R-PFA-8876789 CARNMT1 methylates CARN to Anserine IEA Plasmodium falciparum 59789 R-PFA-8879123 https://reactome.org/PathwayBrowser/#/R-PFA-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Plasmodium falciparum 59789 R-PFA-8932413 https://reactome.org/PathwayBrowser/#/R-PFA-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Plasmodium falciparum 59789 R-RNO-1483174 https://reactome.org/PathwayBrowser/#/R-RNO-1483174 PE is methylated to PC by PEMT IEA Rattus norvegicus 59789 R-RNO-158609 https://reactome.org/PathwayBrowser/#/R-RNO-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Rattus norvegicus 59789 R-RNO-174391 https://reactome.org/PathwayBrowser/#/R-RNO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Rattus norvegicus 59789 R-RNO-175983 https://reactome.org/PathwayBrowser/#/R-RNO-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Rattus norvegicus 59789 R-RNO-175987 https://reactome.org/PathwayBrowser/#/R-RNO-175987 NNMT transfers CH3 from AdoMet to PY IEA Rattus norvegicus 59789 R-RNO-191790 https://reactome.org/PathwayBrowser/#/R-RNO-191790 Loading and methylation of Sm proteins onto SMN Complexes IEA Rattus norvegicus 59789 R-RNO-209821 https://reactome.org/PathwayBrowser/#/R-RNO-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Rattus norvegicus 59789 R-RNO-209903 https://reactome.org/PathwayBrowser/#/R-RNO-209903 Noradrenaline is converted to adrenaline IEA Rattus norvegicus 59789 R-RNO-212263 https://reactome.org/PathwayBrowser/#/R-RNO-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Rattus norvegicus 59789 R-RNO-212269 https://reactome.org/PathwayBrowser/#/R-RNO-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Rattus norvegicus 59789 R-RNO-2162186 https://reactome.org/PathwayBrowser/#/R-RNO-2162186 COQ3 methylates DeMQ10H2 IEA Rattus norvegicus 59789 R-RNO-2162188 https://reactome.org/PathwayBrowser/#/R-RNO-2162188 COQ5 methylates MDMQ10H2 IEA Rattus norvegicus 59789 R-RNO-2162193 https://reactome.org/PathwayBrowser/#/R-RNO-2162193 COQ3 methylates DHDB IEA Rattus norvegicus 59789 R-RNO-2301205 https://reactome.org/PathwayBrowser/#/R-RNO-2301205 SETD8 monomethylates histone H4 IEA Rattus norvegicus 59789 R-RNO-2408501 https://reactome.org/PathwayBrowser/#/R-RNO-2408501 MeSeH is methylated to Me2Se by MeSeH methyltransferase TAS Rattus norvegicus 59789 R-RNO-2408511 https://reactome.org/PathwayBrowser/#/R-RNO-2408511 H2Se is methylated to MeSeH by H2Se methyltransferase TAS Rattus norvegicus 59789 R-RNO-3149518 https://reactome.org/PathwayBrowser/#/R-RNO-3149518 MTRR reduces cob(II)alamin to meCbl IEA Rattus norvegicus 59789 R-RNO-3222237 https://reactome.org/PathwayBrowser/#/R-RNO-3222237 SMYD2 methylates TP53 IEA Rattus norvegicus 59789 R-RNO-3240295 https://reactome.org/PathwayBrowser/#/R-RNO-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Rattus norvegicus 59789 R-RNO-351222 https://reactome.org/PathwayBrowser/#/R-RNO-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Rattus norvegicus 59789 R-RNO-3788745 https://reactome.org/PathwayBrowser/#/R-RNO-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Rattus norvegicus 59789 R-RNO-3788748 https://reactome.org/PathwayBrowser/#/R-RNO-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Rattus norvegicus 59789 R-RNO-379387 https://reactome.org/PathwayBrowser/#/R-RNO-379387 COMT transfers Met to DA to form 3MT IEA Rattus norvegicus 59789 R-RNO-379464 https://reactome.org/PathwayBrowser/#/R-RNO-379464 COMT transfers Met to DOPAC to form HVA IEA Rattus norvegicus 59789 R-RNO-427527 https://reactome.org/PathwayBrowser/#/R-RNO-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Rattus norvegicus 59789 R-RNO-4827382 https://reactome.org/PathwayBrowser/#/R-RNO-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Rattus norvegicus 59789 R-RNO-4827383 https://reactome.org/PathwayBrowser/#/R-RNO-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Rattus norvegicus 59789 R-RNO-5159245 https://reactome.org/PathwayBrowser/#/R-RNO-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus 59789 R-RNO-5205798 https://reactome.org/PathwayBrowser/#/R-RNO-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Rattus norvegicus 59789 R-RNO-5205799 https://reactome.org/PathwayBrowser/#/R-RNO-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Rattus norvegicus 59789 R-RNO-5205822 https://reactome.org/PathwayBrowser/#/R-RNO-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 IEA Rattus norvegicus 59789 R-RNO-5205824 https://reactome.org/PathwayBrowser/#/R-RNO-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Rattus norvegicus 59789 R-RNO-5205861 https://reactome.org/PathwayBrowser/#/R-RNO-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Rattus norvegicus 59789 R-RNO-5205867 https://reactome.org/PathwayBrowser/#/R-RNO-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Rattus norvegicus 59789 R-RNO-5218952 https://reactome.org/PathwayBrowser/#/R-RNO-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Rattus norvegicus 59789 R-RNO-5229010 https://reactome.org/PathwayBrowser/#/R-RNO-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) IEA Rattus norvegicus 59789 R-RNO-5244692 https://reactome.org/PathwayBrowser/#/R-RNO-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus 59789 R-RNO-5333614 https://reactome.org/PathwayBrowser/#/R-RNO-5333614 GSSebGalNac is reduced and methylated to MeSebGalNac TAS Rattus norvegicus 59789 R-RNO-5358484 https://reactome.org/PathwayBrowser/#/R-RNO-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Rattus norvegicus 59789 R-RNO-5359451 https://reactome.org/PathwayBrowser/#/R-RNO-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Rattus norvegicus 59789 R-RNO-5423038 https://reactome.org/PathwayBrowser/#/R-RNO-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Rattus norvegicus 59789 R-RNO-5603114 https://reactome.org/PathwayBrowser/#/R-RNO-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Rattus norvegicus 59789 R-RNO-5634729 https://reactome.org/PathwayBrowser/#/R-RNO-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Rattus norvegicus 59789 R-RNO-5634750 https://reactome.org/PathwayBrowser/#/R-RNO-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Rattus norvegicus 59789 R-RNO-5634802 https://reactome.org/PathwayBrowser/#/R-RNO-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Rattus norvegicus 59789 R-RNO-5637686 https://reactome.org/PathwayBrowser/#/R-RNO-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus 59789 R-RNO-5638141 https://reactome.org/PathwayBrowser/#/R-RNO-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) IEA Rattus norvegicus 59789 R-RNO-5638157 https://reactome.org/PathwayBrowser/#/R-RNO-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Rattus norvegicus 59789 R-RNO-5638332 https://reactome.org/PathwayBrowser/#/R-RNO-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Rattus norvegicus 59789 R-RNO-5638333 https://reactome.org/PathwayBrowser/#/R-RNO-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Rattus norvegicus 59789 R-RNO-5649764 https://reactome.org/PathwayBrowser/#/R-RNO-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Rattus norvegicus 59789 R-RNO-5649799 https://reactome.org/PathwayBrowser/#/R-RNO-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Rattus norvegicus 59789 R-RNO-5649800 https://reactome.org/PathwayBrowser/#/R-RNO-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Rattus norvegicus 59789 R-RNO-5649801 https://reactome.org/PathwayBrowser/#/R-RNO-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Rattus norvegicus 59789 R-RNO-5649802 https://reactome.org/PathwayBrowser/#/R-RNO-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Rattus norvegicus 59789 R-RNO-5651654 https://reactome.org/PathwayBrowser/#/R-RNO-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Rattus norvegicus 59789 R-RNO-5651657 https://reactome.org/PathwayBrowser/#/R-RNO-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Rattus norvegicus 59789 R-RNO-5661117 https://reactome.org/PathwayBrowser/#/R-RNO-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Rattus norvegicus 59789 R-RNO-5661126 https://reactome.org/PathwayBrowser/#/R-RNO-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Rattus norvegicus 59789 R-RNO-5676966 https://reactome.org/PathwayBrowser/#/R-RNO-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Rattus norvegicus 59789 R-RNO-5682965 https://reactome.org/PathwayBrowser/#/R-RNO-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Rattus norvegicus 59789 R-RNO-5696213 https://reactome.org/PathwayBrowser/#/R-RNO-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Rattus norvegicus 59789 R-RNO-5696220 https://reactome.org/PathwayBrowser/#/R-RNO-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Rattus norvegicus 59789 R-RNO-6786205 https://reactome.org/PathwayBrowser/#/R-RNO-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Rattus norvegicus 59789 R-RNO-6788650 https://reactome.org/PathwayBrowser/#/R-RNO-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Rattus norvegicus 59789 R-RNO-6793591 https://reactome.org/PathwayBrowser/#/R-RNO-6793591 LIAS synthesizes lipoyl-GCSH IEA Rattus norvegicus 59789 R-RNO-6798317 https://reactome.org/PathwayBrowser/#/R-RNO-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Rattus norvegicus 59789 R-RNO-6804383 https://reactome.org/PathwayBrowser/#/R-RNO-6804383 PRMT5 methylates TP53 IEA Rattus norvegicus 59789 R-RNO-6805740 https://reactome.org/PathwayBrowser/#/R-RNO-6805740 SETD8 methylates TP53 IEA Rattus norvegicus 59789 R-RNO-6805755 https://reactome.org/PathwayBrowser/#/R-RNO-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Rattus norvegicus 59789 R-RNO-71286 https://reactome.org/PathwayBrowser/#/R-RNO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Rattus norvegicus 59789 R-RNO-77090 https://reactome.org/PathwayBrowser/#/R-RNO-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Rattus norvegicus 59789 R-RNO-8855062 https://reactome.org/PathwayBrowser/#/R-RNO-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Rattus norvegicus 59789 R-RNO-8856945 https://reactome.org/PathwayBrowser/#/R-RNO-8856945 PP2A methylation by LCMT1 IEA Rattus norvegicus 59789 R-RNO-8865237 https://reactome.org/PathwayBrowser/#/R-RNO-8865237 SETD6 methylates RELA in the NFkB complex IEA Rattus norvegicus 59789 R-RNO-8876789 https://reactome.org/PathwayBrowser/#/R-RNO-8876789 CARNMT1 methylates CARN to Anserine IEA Rattus norvegicus 59789 R-RNO-8879123 https://reactome.org/PathwayBrowser/#/R-RNO-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Rattus norvegicus 59789 R-RNO-8931858 https://reactome.org/PathwayBrowser/#/R-RNO-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Rattus norvegicus 59789 R-RNO-8931974 https://reactome.org/PathwayBrowser/#/R-RNO-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Rattus norvegicus 59789 R-RNO-8932221 https://reactome.org/PathwayBrowser/#/R-RNO-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Rattus norvegicus 59789 R-RNO-8932243 https://reactome.org/PathwayBrowser/#/R-RNO-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Rattus norvegicus 59789 R-RNO-8932275 https://reactome.org/PathwayBrowser/#/R-RNO-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Rattus norvegicus 59789 R-RNO-8934735 https://reactome.org/PathwayBrowser/#/R-RNO-8934735 PRMT1 arginine-methylates RUNX1 IEA Rattus norvegicus 59789 R-RNO-8936481 https://reactome.org/PathwayBrowser/#/R-RNO-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Rattus norvegicus 59789 R-RNO-8936584 https://reactome.org/PathwayBrowser/#/R-RNO-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Rattus norvegicus 59789 R-RNO-8936608 https://reactome.org/PathwayBrowser/#/R-RNO-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Rattus norvegicus 59789 R-RNO-8936621 https://reactome.org/PathwayBrowser/#/R-RNO-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Rattus norvegicus 59789 R-RNO-8937016 https://reactome.org/PathwayBrowser/#/R-RNO-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Rattus norvegicus 59789 R-RNO-8937022 https://reactome.org/PathwayBrowser/#/R-RNO-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Rattus norvegicus 59789 R-RNO-8937050 https://reactome.org/PathwayBrowser/#/R-RNO-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Rattus norvegicus 59789 R-RNO-8937113 https://reactome.org/PathwayBrowser/#/R-RNO-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Rattus norvegicus 59789 R-RNO-8955010 https://reactome.org/PathwayBrowser/#/R-RNO-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Rattus norvegicus 59789 R-RNO-947535 https://reactome.org/PathwayBrowser/#/R-RNO-947535 Cyclisation of GTP to precursor Z IEA Rattus norvegicus 59789 R-RNO-9632182 https://reactome.org/PathwayBrowser/#/R-RNO-9632182 PRMT1 methylates ESRs IEA Rattus norvegicus 59789 R-RNO-9640254 https://reactome.org/PathwayBrowser/#/R-RNO-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Rattus norvegicus 59789 R-RNO-9647977 https://reactome.org/PathwayBrowser/#/R-RNO-9647977 ICMT methylates S-Farn RAS proteins IEA Rattus norvegicus 59789 R-RNO-9748979 https://reactome.org/PathwayBrowser/#/R-RNO-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Rattus norvegicus 59789 R-RNO-9748983 https://reactome.org/PathwayBrowser/#/R-RNO-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Rattus norvegicus 59789 R-SCE-1483174 https://reactome.org/PathwayBrowser/#/R-SCE-1483174 PE is methylated to PC by PEMT IEA Saccharomyces cerevisiae 59789 R-SCE-174391 https://reactome.org/PathwayBrowser/#/R-SCE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Saccharomyces cerevisiae 59789 R-SCE-2162186 https://reactome.org/PathwayBrowser/#/R-SCE-2162186 COQ3 methylates DeMQ10H2 IEA Saccharomyces cerevisiae 59789 R-SCE-2162188 https://reactome.org/PathwayBrowser/#/R-SCE-2162188 COQ5 methylates MDMQ10H2 IEA Saccharomyces cerevisiae 59789 R-SCE-2162193 https://reactome.org/PathwayBrowser/#/R-SCE-2162193 COQ3 methylates DHDB IEA Saccharomyces cerevisiae 59789 R-SCE-351222 https://reactome.org/PathwayBrowser/#/R-SCE-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Saccharomyces cerevisiae 59789 R-SCE-427527 https://reactome.org/PathwayBrowser/#/R-SCE-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Saccharomyces cerevisiae 59789 R-SCE-4827382 https://reactome.org/PathwayBrowser/#/R-SCE-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Saccharomyces cerevisiae 59789 R-SCE-4827383 https://reactome.org/PathwayBrowser/#/R-SCE-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Saccharomyces cerevisiae 59789 R-SCE-5159245 https://reactome.org/PathwayBrowser/#/R-SCE-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Saccharomyces cerevisiae 59789 R-SCE-5205798 https://reactome.org/PathwayBrowser/#/R-SCE-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Saccharomyces cerevisiae 59789 R-SCE-5205867 https://reactome.org/PathwayBrowser/#/R-SCE-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Saccharomyces cerevisiae 59789 R-SCE-5244692 https://reactome.org/PathwayBrowser/#/R-SCE-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Saccharomyces cerevisiae 59789 R-SCE-5358484 https://reactome.org/PathwayBrowser/#/R-SCE-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Saccharomyces cerevisiae 59789 R-SCE-5358494 https://reactome.org/PathwayBrowser/#/R-SCE-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Saccharomyces cerevisiae 59789 R-SCE-5637686 https://reactome.org/PathwayBrowser/#/R-SCE-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Saccharomyces cerevisiae 59789 R-SCE-5638157 https://reactome.org/PathwayBrowser/#/R-SCE-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Saccharomyces cerevisiae 59789 R-SCE-5638333 https://reactome.org/PathwayBrowser/#/R-SCE-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Saccharomyces cerevisiae 59789 R-SCE-5649764 https://reactome.org/PathwayBrowser/#/R-SCE-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Saccharomyces cerevisiae 59789 R-SCE-5649799 https://reactome.org/PathwayBrowser/#/R-SCE-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Saccharomyces cerevisiae 59789 R-SCE-5649800 https://reactome.org/PathwayBrowser/#/R-SCE-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Saccharomyces cerevisiae 59789 R-SCE-5649801 https://reactome.org/PathwayBrowser/#/R-SCE-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Saccharomyces cerevisiae 59789 R-SCE-5649802 https://reactome.org/PathwayBrowser/#/R-SCE-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Saccharomyces cerevisiae 59789 R-SCE-5661126 https://reactome.org/PathwayBrowser/#/R-SCE-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Saccharomyces cerevisiae 59789 R-SCE-5682965 https://reactome.org/PathwayBrowser/#/R-SCE-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Saccharomyces cerevisiae 59789 R-SCE-6783393 https://reactome.org/PathwayBrowser/#/R-SCE-6783393 PPM2 methoxycarbonylates yW-58 yielding yW at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 59789 R-SCE-6783396 https://reactome.org/PathwayBrowser/#/R-SCE-6783396 TRM5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 59789 R-SCE-6783410 https://reactome.org/PathwayBrowser/#/R-SCE-6783410 TRM12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 59789 R-SCE-6783417 https://reactome.org/PathwayBrowser/#/R-SCE-6783417 PPM2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 59789 R-SCE-6783426 https://reactome.org/PathwayBrowser/#/R-SCE-6783426 TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 59789 R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 59789 R-SCE-6786492 https://reactome.org/PathwayBrowser/#/R-SCE-6786492 TRM11:TRM112 methylates guanosine-10 in tRNA yielding N(2)-methylguanosine-10 TAS Saccharomyces cerevisiae 59789 R-SCE-6786632 https://reactome.org/PathwayBrowser/#/R-SCE-6786632 TRM10 methylates guanosine-9 in tRNA TAS Saccharomyces cerevisiae 59789 R-SCE-6788650 https://reactome.org/PathwayBrowser/#/R-SCE-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Saccharomyces cerevisiae 59789 R-SCE-6788665 https://reactome.org/PathwayBrowser/#/R-SCE-6788665 TRM13 2'-O-methylates adenosine-4 in tRNA TAS Saccharomyces cerevisiae 59789 R-SCE-6788673 https://reactome.org/PathwayBrowser/#/R-SCE-6788673 TRM44 2'-O-methylates uridine-44 in tRNA(Ser) TAS Saccharomyces cerevisiae 59789 R-SCE-6788683 https://reactome.org/PathwayBrowser/#/R-SCE-6788683 TRM13 2'-O-methylates cytidine-4 in tRNA TAS Saccharomyces cerevisiae 59789 R-SCE-6790149 https://reactome.org/PathwayBrowser/#/R-SCE-6790149 NCL1 (TRM4) methylates cytidine-49 of tRNA(Asp) yielding 5-methylcytidine-46 TAS Saccharomyces cerevisiae 59789 R-SCE-6790171 https://reactome.org/PathwayBrowser/#/R-SCE-6790171 TRM9 methylates 5-carboxymethyluridine-34 in tRNA(Arg3) yielding 5-methoxycarbonylmethyluridine-34 TAS Saccharomyces cerevisiae 59789 R-SCE-6790175 https://reactome.org/PathwayBrowser/#/R-SCE-6790175 TRM8:TRM82 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 TAS Saccharomyces cerevisiae 59789 R-SCE-6790189 https://reactome.org/PathwayBrowser/#/R-SCE-6790189 NCL1 (TRM4) methylates cytidine-34 of unspliced tRNA(Leu) yielding 5-methylcytidine-34 TAS Saccharomyces cerevisiae 59789 R-SCE-6790936 https://reactome.org/PathwayBrowser/#/R-SCE-6790936 EMG1 of the SSU processome methylates pseudouridine-1191 of 18S rRNA yielding N(1)-methylpseudouridine-1191 TAS Saccharomyces cerevisiae 59789 R-SCE-6790942 https://reactome.org/PathwayBrowser/#/R-SCE-6790942 NOP2 methylates cytosine-2870 of 25S rRNA yielding 5-methylcytosine-2870 TAS Saccharomyces cerevisiae 59789 R-SCE-6793739 https://reactome.org/PathwayBrowser/#/R-SCE-6793739 Box C/D snoRNP methylates ribonucleotides in pre-rRNA TAS Saccharomyces cerevisiae 59789 R-SCE-6800138 https://reactome.org/PathwayBrowser/#/R-SCE-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Saccharomyces cerevisiae 59789 R-SCE-6800149 https://reactome.org/PathwayBrowser/#/R-SCE-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Saccharomyces cerevisiae 59789 R-SCE-71286 https://reactome.org/PathwayBrowser/#/R-SCE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Saccharomyces cerevisiae 59789 R-SCE-77090 https://reactome.org/PathwayBrowser/#/R-SCE-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Saccharomyces cerevisiae 59789 R-SCE-8855062 https://reactome.org/PathwayBrowser/#/R-SCE-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Saccharomyces cerevisiae 59789 R-SCE-8856945 https://reactome.org/PathwayBrowser/#/R-SCE-8856945 PP2A methylation by LCMT1 IEA Saccharomyces cerevisiae 59789 R-SCE-8876789 https://reactome.org/PathwayBrowser/#/R-SCE-8876789 CARNMT1 methylates CARN to Anserine IEA Saccharomyces cerevisiae 59789 R-SCE-8879123 https://reactome.org/PathwayBrowser/#/R-SCE-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Saccharomyces cerevisiae 59789 R-SCE-8931974 https://reactome.org/PathwayBrowser/#/R-SCE-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Saccharomyces cerevisiae 59789 R-SCE-8932221 https://reactome.org/PathwayBrowser/#/R-SCE-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Saccharomyces cerevisiae 59789 R-SCE-8932243 https://reactome.org/PathwayBrowser/#/R-SCE-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Saccharomyces cerevisiae 59789 R-SCE-8932276 https://reactome.org/PathwayBrowser/#/R-SCE-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Saccharomyces cerevisiae 59789 R-SCE-8932413 https://reactome.org/PathwayBrowser/#/R-SCE-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Saccharomyces cerevisiae 59789 R-SPO-1483174 https://reactome.org/PathwayBrowser/#/R-SPO-1483174 PE is methylated to PC by PEMT IEA Schizosaccharomyces pombe 59789 R-SPO-174391 https://reactome.org/PathwayBrowser/#/R-SPO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Schizosaccharomyces pombe 59789 R-SPO-175983 https://reactome.org/PathwayBrowser/#/R-SPO-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Schizosaccharomyces pombe 59789 R-SPO-2162186 https://reactome.org/PathwayBrowser/#/R-SPO-2162186 COQ3 methylates DeMQ10H2 IEA Schizosaccharomyces pombe 59789 R-SPO-2162188 https://reactome.org/PathwayBrowser/#/R-SPO-2162188 COQ5 methylates MDMQ10H2 IEA Schizosaccharomyces pombe 59789 R-SPO-2162193 https://reactome.org/PathwayBrowser/#/R-SPO-2162193 COQ3 methylates DHDB IEA Schizosaccharomyces pombe 59789 R-SPO-351222 https://reactome.org/PathwayBrowser/#/R-SPO-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Schizosaccharomyces pombe 59789 R-SPO-379387 https://reactome.org/PathwayBrowser/#/R-SPO-379387 COMT transfers Met to DA to form 3MT IEA Schizosaccharomyces pombe 59789 R-SPO-379464 https://reactome.org/PathwayBrowser/#/R-SPO-379464 COMT transfers Met to DOPAC to form HVA IEA Schizosaccharomyces pombe 59789 R-SPO-427527 https://reactome.org/PathwayBrowser/#/R-SPO-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Schizosaccharomyces pombe 59789 R-SPO-4827382 https://reactome.org/PathwayBrowser/#/R-SPO-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Schizosaccharomyces pombe 59789 R-SPO-4827383 https://reactome.org/PathwayBrowser/#/R-SPO-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Schizosaccharomyces pombe 59789 R-SPO-5159245 https://reactome.org/PathwayBrowser/#/R-SPO-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Schizosaccharomyces pombe 59789 R-SPO-5205798 https://reactome.org/PathwayBrowser/#/R-SPO-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Schizosaccharomyces pombe 59789 R-SPO-5205799 https://reactome.org/PathwayBrowser/#/R-SPO-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Schizosaccharomyces pombe 59789 R-SPO-5205867 https://reactome.org/PathwayBrowser/#/R-SPO-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Schizosaccharomyces pombe 59789 R-SPO-5244692 https://reactome.org/PathwayBrowser/#/R-SPO-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Schizosaccharomyces pombe 59789 R-SPO-5358484 https://reactome.org/PathwayBrowser/#/R-SPO-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Schizosaccharomyces pombe 59789 R-SPO-5358494 https://reactome.org/PathwayBrowser/#/R-SPO-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Schizosaccharomyces pombe 59789 R-SPO-5634802 https://reactome.org/PathwayBrowser/#/R-SPO-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Schizosaccharomyces pombe 59789 R-SPO-5637686 https://reactome.org/PathwayBrowser/#/R-SPO-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Schizosaccharomyces pombe 59789 R-SPO-5638157 https://reactome.org/PathwayBrowser/#/R-SPO-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Schizosaccharomyces pombe 59789 R-SPO-5638333 https://reactome.org/PathwayBrowser/#/R-SPO-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Schizosaccharomyces pombe 59789 R-SPO-5649800 https://reactome.org/PathwayBrowser/#/R-SPO-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Schizosaccharomyces pombe 59789 R-SPO-5649802 https://reactome.org/PathwayBrowser/#/R-SPO-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Schizosaccharomyces pombe 59789 R-SPO-5651654 https://reactome.org/PathwayBrowser/#/R-SPO-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Schizosaccharomyces pombe 59789 R-SPO-5651657 https://reactome.org/PathwayBrowser/#/R-SPO-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Schizosaccharomyces pombe 59789 R-SPO-5661117 https://reactome.org/PathwayBrowser/#/R-SPO-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Schizosaccharomyces pombe 59789 R-SPO-5661126 https://reactome.org/PathwayBrowser/#/R-SPO-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Schizosaccharomyces pombe 59789 R-SPO-5676966 https://reactome.org/PathwayBrowser/#/R-SPO-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Schizosaccharomyces pombe 59789 R-SPO-5682965 https://reactome.org/PathwayBrowser/#/R-SPO-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Schizosaccharomyces pombe 59789 R-SPO-6788650 https://reactome.org/PathwayBrowser/#/R-SPO-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Schizosaccharomyces pombe 59789 R-SPO-6800138 https://reactome.org/PathwayBrowser/#/R-SPO-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Schizosaccharomyces pombe 59789 R-SPO-6800149 https://reactome.org/PathwayBrowser/#/R-SPO-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Schizosaccharomyces pombe 59789 R-SPO-71286 https://reactome.org/PathwayBrowser/#/R-SPO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Schizosaccharomyces pombe 59789 R-SPO-77090 https://reactome.org/PathwayBrowser/#/R-SPO-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Schizosaccharomyces pombe 59789 R-SPO-8855062 https://reactome.org/PathwayBrowser/#/R-SPO-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Schizosaccharomyces pombe 59789 R-SPO-8856945 https://reactome.org/PathwayBrowser/#/R-SPO-8856945 PP2A methylation by LCMT1 IEA Schizosaccharomyces pombe 59789 R-SPO-8876789 https://reactome.org/PathwayBrowser/#/R-SPO-8876789 CARNMT1 methylates CARN to Anserine IEA Schizosaccharomyces pombe 59789 R-SPO-8879123 https://reactome.org/PathwayBrowser/#/R-SPO-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Schizosaccharomyces pombe 59789 R-SPO-8932221 https://reactome.org/PathwayBrowser/#/R-SPO-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Schizosaccharomyces pombe 59789 R-SPO-8932243 https://reactome.org/PathwayBrowser/#/R-SPO-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Schizosaccharomyces pombe 59789 R-SPO-8932276 https://reactome.org/PathwayBrowser/#/R-SPO-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Schizosaccharomyces pombe 59789 R-SPO-8932413 https://reactome.org/PathwayBrowser/#/R-SPO-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Schizosaccharomyces pombe 59789 R-SPO-8955010 https://reactome.org/PathwayBrowser/#/R-SPO-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Schizosaccharomyces pombe 59789 R-SSC-1483174 https://reactome.org/PathwayBrowser/#/R-SSC-1483174 PE is methylated to PC by PEMT IEA Sus scrofa 59789 R-SSC-158609 https://reactome.org/PathwayBrowser/#/R-SSC-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Sus scrofa 59789 R-SSC-174391 https://reactome.org/PathwayBrowser/#/R-SSC-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Sus scrofa 59789 R-SSC-175983 https://reactome.org/PathwayBrowser/#/R-SSC-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Sus scrofa 59789 R-SSC-175987 https://reactome.org/PathwayBrowser/#/R-SSC-175987 NNMT transfers CH3 from AdoMet to PY IEA Sus scrofa 59789 R-SSC-191790 https://reactome.org/PathwayBrowser/#/R-SSC-191790 Loading and methylation of Sm proteins onto SMN Complexes IEA Sus scrofa 59789 R-SSC-209821 https://reactome.org/PathwayBrowser/#/R-SSC-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Sus scrofa 59789 R-SSC-209903 https://reactome.org/PathwayBrowser/#/R-SSC-209903 Noradrenaline is converted to adrenaline IEA Sus scrofa 59789 R-SSC-212263 https://reactome.org/PathwayBrowser/#/R-SSC-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Sus scrofa 59789 R-SSC-212269 https://reactome.org/PathwayBrowser/#/R-SSC-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Sus scrofa 59789 R-SSC-2162186 https://reactome.org/PathwayBrowser/#/R-SSC-2162186 COQ3 methylates DeMQ10H2 IEA Sus scrofa 59789 R-SSC-2162188 https://reactome.org/PathwayBrowser/#/R-SSC-2162188 COQ5 methylates MDMQ10H2 IEA Sus scrofa 59789 R-SSC-2162193 https://reactome.org/PathwayBrowser/#/R-SSC-2162193 COQ3 methylates DHDB IEA Sus scrofa 59789 R-SSC-2301205 https://reactome.org/PathwayBrowser/#/R-SSC-2301205 SETD8 monomethylates histone H4 IEA Sus scrofa 59789 R-SSC-3149518 https://reactome.org/PathwayBrowser/#/R-SSC-3149518 MTRR reduces cob(II)alamin to meCbl IEA Sus scrofa 59789 R-SSC-3222237 https://reactome.org/PathwayBrowser/#/R-SSC-3222237 SMYD2 methylates TP53 IEA Sus scrofa 59789 R-SSC-3240295 https://reactome.org/PathwayBrowser/#/R-SSC-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Sus scrofa 59789 R-SSC-351222 https://reactome.org/PathwayBrowser/#/R-SSC-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Sus scrofa 59789 R-SSC-3788745 https://reactome.org/PathwayBrowser/#/R-SSC-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Sus scrofa 59789 R-SSC-3788748 https://reactome.org/PathwayBrowser/#/R-SSC-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Sus scrofa 59789 R-SSC-379387 https://reactome.org/PathwayBrowser/#/R-SSC-379387 COMT transfers Met to DA to form 3MT IEA Sus scrofa 59789 R-SSC-379464 https://reactome.org/PathwayBrowser/#/R-SSC-379464 COMT transfers Met to DOPAC to form HVA IEA Sus scrofa 59789 R-SSC-427527 https://reactome.org/PathwayBrowser/#/R-SSC-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Sus scrofa 59789 R-SSC-4827382 https://reactome.org/PathwayBrowser/#/R-SSC-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Sus scrofa 59789 R-SSC-4827383 https://reactome.org/PathwayBrowser/#/R-SSC-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Sus scrofa 59789 R-SSC-5159245 https://reactome.org/PathwayBrowser/#/R-SSC-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Sus scrofa 59789 R-SSC-5205798 https://reactome.org/PathwayBrowser/#/R-SSC-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Sus scrofa 59789 R-SSC-5205799 https://reactome.org/PathwayBrowser/#/R-SSC-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Sus scrofa 59789 R-SSC-5205820 https://reactome.org/PathwayBrowser/#/R-SSC-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Sus scrofa 59789 R-SSC-5205822 https://reactome.org/PathwayBrowser/#/R-SSC-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 IEA Sus scrofa 59789 R-SSC-5205824 https://reactome.org/PathwayBrowser/#/R-SSC-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Sus scrofa 59789 R-SSC-5205861 https://reactome.org/PathwayBrowser/#/R-SSC-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Sus scrofa 59789 R-SSC-5205867 https://reactome.org/PathwayBrowser/#/R-SSC-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Sus scrofa 59789 R-SSC-5216234 https://reactome.org/PathwayBrowser/#/R-SSC-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Sus scrofa 59789 R-SSC-5218952 https://reactome.org/PathwayBrowser/#/R-SSC-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Sus scrofa 59789 R-SSC-5229010 https://reactome.org/PathwayBrowser/#/R-SSC-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) IEA Sus scrofa 59789 R-SSC-5229203 https://reactome.org/PathwayBrowser/#/R-SSC-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Sus scrofa 59789 R-SSC-5244692 https://reactome.org/PathwayBrowser/#/R-SSC-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Sus scrofa 59789 R-SSC-5358484 https://reactome.org/PathwayBrowser/#/R-SSC-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Sus scrofa 59789 R-SSC-5358494 https://reactome.org/PathwayBrowser/#/R-SSC-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Sus scrofa 59789 R-SSC-5359451 https://reactome.org/PathwayBrowser/#/R-SSC-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Sus scrofa 59789 R-SSC-5423038 https://reactome.org/PathwayBrowser/#/R-SSC-5423038 SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) IEA Sus scrofa 59789 R-SSC-5603114 https://reactome.org/PathwayBrowser/#/R-SSC-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Sus scrofa 59789 R-SSC-5634729 https://reactome.org/PathwayBrowser/#/R-SSC-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Sus scrofa 59789 R-SSC-5634750 https://reactome.org/PathwayBrowser/#/R-SSC-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Sus scrofa 59789 R-SSC-5634802 https://reactome.org/PathwayBrowser/#/R-SSC-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Sus scrofa 59789 R-SSC-5637686 https://reactome.org/PathwayBrowser/#/R-SSC-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Sus scrofa 59789 R-SSC-5638141 https://reactome.org/PathwayBrowser/#/R-SSC-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) IEA Sus scrofa 59789 R-SSC-5638157 https://reactome.org/PathwayBrowser/#/R-SSC-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Sus scrofa 59789 R-SSC-5638332 https://reactome.org/PathwayBrowser/#/R-SSC-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Sus scrofa 59789 R-SSC-5638333 https://reactome.org/PathwayBrowser/#/R-SSC-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Sus scrofa 59789 R-SSC-5649764 https://reactome.org/PathwayBrowser/#/R-SSC-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Sus scrofa 59789 R-SSC-5649799 https://reactome.org/PathwayBrowser/#/R-SSC-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Sus scrofa 59789 R-SSC-5649800 https://reactome.org/PathwayBrowser/#/R-SSC-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Sus scrofa 59789 R-SSC-5649801 https://reactome.org/PathwayBrowser/#/R-SSC-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Sus scrofa 59789 R-SSC-5649802 https://reactome.org/PathwayBrowser/#/R-SSC-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Sus scrofa 59789 R-SSC-5651654 https://reactome.org/PathwayBrowser/#/R-SSC-5651654 SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) IEA Sus scrofa 59789 R-SSC-5651657 https://reactome.org/PathwayBrowser/#/R-SSC-5651657 SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) IEA Sus scrofa 59789 R-SSC-5661117 https://reactome.org/PathwayBrowser/#/R-SSC-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Sus scrofa 59789 R-SSC-5661126 https://reactome.org/PathwayBrowser/#/R-SSC-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Sus scrofa 59789 R-SSC-5676966 https://reactome.org/PathwayBrowser/#/R-SSC-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Sus scrofa 59789 R-SSC-5682965 https://reactome.org/PathwayBrowser/#/R-SSC-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Sus scrofa 59789 R-SSC-5696213 https://reactome.org/PathwayBrowser/#/R-SSC-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Sus scrofa 59789 R-SSC-5696220 https://reactome.org/PathwayBrowser/#/R-SSC-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Sus scrofa 59789 R-SSC-6786205 https://reactome.org/PathwayBrowser/#/R-SSC-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Sus scrofa 59789 R-SSC-6793591 https://reactome.org/PathwayBrowser/#/R-SSC-6793591 LIAS synthesizes lipoyl-GCSH IEA Sus scrofa 59789 R-SSC-6798317 https://reactome.org/PathwayBrowser/#/R-SSC-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Sus scrofa 59789 R-SSC-6800138 https://reactome.org/PathwayBrowser/#/R-SSC-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer IEA Sus scrofa 59789 R-SSC-6800149 https://reactome.org/PathwayBrowser/#/R-SSC-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Sus scrofa 59789 R-SSC-6804383 https://reactome.org/PathwayBrowser/#/R-SSC-6804383 PRMT5 methylates TP53 IEA Sus scrofa 59789 R-SSC-6805730 https://reactome.org/PathwayBrowser/#/R-SSC-6805730 SETD9 methylates TP53 IEA Sus scrofa 59789 R-SSC-6805740 https://reactome.org/PathwayBrowser/#/R-SSC-6805740 SETD8 methylates TP53 IEA Sus scrofa 59789 R-SSC-6805755 https://reactome.org/PathwayBrowser/#/R-SSC-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Sus scrofa 59789 R-SSC-71286 https://reactome.org/PathwayBrowser/#/R-SSC-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Sus scrofa 59789 R-SSC-77090 https://reactome.org/PathwayBrowser/#/R-SSC-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Sus scrofa 59789 R-SSC-8855062 https://reactome.org/PathwayBrowser/#/R-SSC-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Sus scrofa 59789 R-SSC-8856945 https://reactome.org/PathwayBrowser/#/R-SSC-8856945 PP2A methylation by LCMT1 IEA Sus scrofa 59789 R-SSC-8865237 https://reactome.org/PathwayBrowser/#/R-SSC-8865237 SETD6 methylates RELA in the NFkB complex IEA Sus scrofa 59789 R-SSC-8876789 https://reactome.org/PathwayBrowser/#/R-SSC-8876789 CARNMT1 methylates CARN to Anserine IEA Sus scrofa 59789 R-SSC-8879123 https://reactome.org/PathwayBrowser/#/R-SSC-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Sus scrofa 59789 R-SSC-8931858 https://reactome.org/PathwayBrowser/#/R-SSC-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Sus scrofa 59789 R-SSC-8931974 https://reactome.org/PathwayBrowser/#/R-SSC-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Sus scrofa 59789 R-SSC-8932221 https://reactome.org/PathwayBrowser/#/R-SSC-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Sus scrofa 59789 R-SSC-8932243 https://reactome.org/PathwayBrowser/#/R-SSC-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Sus scrofa 59789 R-SSC-8932275 https://reactome.org/PathwayBrowser/#/R-SSC-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Sus scrofa 59789 R-SSC-8932276 https://reactome.org/PathwayBrowser/#/R-SSC-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Sus scrofa 59789 R-SSC-8932413 https://reactome.org/PathwayBrowser/#/R-SSC-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Sus scrofa 59789 R-SSC-8934735 https://reactome.org/PathwayBrowser/#/R-SSC-8934735 PRMT1 arginine-methylates RUNX1 IEA Sus scrofa 59789 R-SSC-8936481 https://reactome.org/PathwayBrowser/#/R-SSC-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa 59789 R-SSC-8936584 https://reactome.org/PathwayBrowser/#/R-SSC-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa 59789 R-SSC-8936608 https://reactome.org/PathwayBrowser/#/R-SSC-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa 59789 R-SSC-8936621 https://reactome.org/PathwayBrowser/#/R-SSC-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa 59789 R-SSC-8937016 https://reactome.org/PathwayBrowser/#/R-SSC-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa 59789 R-SSC-8937022 https://reactome.org/PathwayBrowser/#/R-SSC-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa 59789 R-SSC-8937050 https://reactome.org/PathwayBrowser/#/R-SSC-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa 59789 R-SSC-8937113 https://reactome.org/PathwayBrowser/#/R-SSC-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa 59789 R-SSC-8955010 https://reactome.org/PathwayBrowser/#/R-SSC-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Sus scrofa 59789 R-SSC-947535 https://reactome.org/PathwayBrowser/#/R-SSC-947535 Cyclisation of GTP to precursor Z IEA Sus scrofa 59789 R-SSC-9632182 https://reactome.org/PathwayBrowser/#/R-SSC-9632182 PRMT1 methylates ESRs IEA Sus scrofa 59789 R-SSC-9640254 https://reactome.org/PathwayBrowser/#/R-SSC-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Sus scrofa 59789 R-SSC-9748979 https://reactome.org/PathwayBrowser/#/R-SSC-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Sus scrofa 59789 R-SSC-9748983 https://reactome.org/PathwayBrowser/#/R-SSC-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Sus scrofa 59789 R-SSC-9854315 https://reactome.org/PathwayBrowser/#/R-SSC-9854315 CSKMT methylates Citrate Synthase IEA Sus scrofa 59789 R-XTR-1483174 https://reactome.org/PathwayBrowser/#/R-XTR-1483174 PE is methylated to PC by PEMT IEA Xenopus tropicalis 59789 R-XTR-158609 https://reactome.org/PathwayBrowser/#/R-XTR-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Xenopus tropicalis 59789 R-XTR-174391 https://reactome.org/PathwayBrowser/#/R-XTR-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Xenopus tropicalis 59789 R-XTR-175983 https://reactome.org/PathwayBrowser/#/R-XTR-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Xenopus tropicalis 59789 R-XTR-175987 https://reactome.org/PathwayBrowser/#/R-XTR-175987 NNMT transfers CH3 from AdoMet to PY IEA Xenopus tropicalis 59789 R-XTR-209821 https://reactome.org/PathwayBrowser/#/R-XTR-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Xenopus tropicalis 59789 R-XTR-212263 https://reactome.org/PathwayBrowser/#/R-XTR-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Xenopus tropicalis 59789 R-XTR-212269 https://reactome.org/PathwayBrowser/#/R-XTR-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Xenopus tropicalis 59789 R-XTR-2162186 https://reactome.org/PathwayBrowser/#/R-XTR-2162186 COQ3 methylates DeMQ10H2 IEA Xenopus tropicalis 59789 R-XTR-2162188 https://reactome.org/PathwayBrowser/#/R-XTR-2162188 COQ5 methylates MDMQ10H2 IEA Xenopus tropicalis 59789 R-XTR-2162193 https://reactome.org/PathwayBrowser/#/R-XTR-2162193 COQ3 methylates DHDB IEA Xenopus tropicalis 59789 R-XTR-2301205 https://reactome.org/PathwayBrowser/#/R-XTR-2301205 SETD8 monomethylates histone H4 IEA Xenopus tropicalis 59789 R-XTR-3240295 https://reactome.org/PathwayBrowser/#/R-XTR-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Xenopus tropicalis 59789 R-XTR-351222 https://reactome.org/PathwayBrowser/#/R-XTR-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Xenopus tropicalis 59789 R-XTR-3788745 https://reactome.org/PathwayBrowser/#/R-XTR-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Xenopus tropicalis 59789 R-XTR-3788748 https://reactome.org/PathwayBrowser/#/R-XTR-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Xenopus tropicalis 59789 R-XTR-379387 https://reactome.org/PathwayBrowser/#/R-XTR-379387 COMT transfers Met to DA to form 3MT IEA Xenopus tropicalis 59789 R-XTR-379464 https://reactome.org/PathwayBrowser/#/R-XTR-379464 COMT transfers Met to DOPAC to form HVA IEA Xenopus tropicalis 59789 R-XTR-5205820 https://reactome.org/PathwayBrowser/#/R-XTR-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Xenopus tropicalis 59789 R-XTR-5205867 https://reactome.org/PathwayBrowser/#/R-XTR-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Xenopus tropicalis 59789 R-XTR-5216234 https://reactome.org/PathwayBrowser/#/R-XTR-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Xenopus tropicalis 59789 R-XTR-5229203 https://reactome.org/PathwayBrowser/#/R-XTR-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Xenopus tropicalis 59789 R-XTR-5358484 https://reactome.org/PathwayBrowser/#/R-XTR-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Xenopus tropicalis 59789 R-XTR-5358494 https://reactome.org/PathwayBrowser/#/R-XTR-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Xenopus tropicalis 59789 R-XTR-5359451 https://reactome.org/PathwayBrowser/#/R-XTR-5359451 NNMT transfers CH3 from SAM to NAM to form MNA IEA Xenopus tropicalis 59789 R-XTR-5603114 https://reactome.org/PathwayBrowser/#/R-XTR-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Xenopus tropicalis 59789 R-XTR-5696213 https://reactome.org/PathwayBrowser/#/R-XTR-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Xenopus tropicalis 59789 R-XTR-5696220 https://reactome.org/PathwayBrowser/#/R-XTR-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) IEA Xenopus tropicalis 59789 R-XTR-6788650 https://reactome.org/PathwayBrowser/#/R-XTR-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Xenopus tropicalis 59789 R-XTR-6798317 https://reactome.org/PathwayBrowser/#/R-XTR-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Xenopus tropicalis 59789 R-XTR-6800149 https://reactome.org/PathwayBrowser/#/R-XTR-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII IEA Xenopus tropicalis 59789 R-XTR-6804383 https://reactome.org/PathwayBrowser/#/R-XTR-6804383 PRMT5 methylates TP53 IEA Xenopus tropicalis 59789 R-XTR-6805740 https://reactome.org/PathwayBrowser/#/R-XTR-6805740 SETD8 methylates TP53 IEA Xenopus tropicalis 59789 R-XTR-6805755 https://reactome.org/PathwayBrowser/#/R-XTR-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Xenopus tropicalis 59789 R-XTR-71286 https://reactome.org/PathwayBrowser/#/R-XTR-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Xenopus tropicalis 59789 R-XTR-8855062 https://reactome.org/PathwayBrowser/#/R-XTR-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Xenopus tropicalis 59789 R-XTR-8856945 https://reactome.org/PathwayBrowser/#/R-XTR-8856945 PP2A methylation by LCMT1 IEA Xenopus tropicalis 59789 R-XTR-8879123 https://reactome.org/PathwayBrowser/#/R-XTR-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Xenopus tropicalis 59789 R-XTR-8931858 https://reactome.org/PathwayBrowser/#/R-XTR-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Xenopus tropicalis 59789 R-XTR-8931974 https://reactome.org/PathwayBrowser/#/R-XTR-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Xenopus tropicalis 59789 R-XTR-8932221 https://reactome.org/PathwayBrowser/#/R-XTR-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Xenopus tropicalis 59789 R-XTR-8932243 https://reactome.org/PathwayBrowser/#/R-XTR-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Xenopus tropicalis 59789 R-XTR-8932275 https://reactome.org/PathwayBrowser/#/R-XTR-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Xenopus tropicalis 59789 R-XTR-8932276 https://reactome.org/PathwayBrowser/#/R-XTR-8932276 VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP IEA Xenopus tropicalis 59789 R-XTR-8936481 https://reactome.org/PathwayBrowser/#/R-XTR-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Xenopus tropicalis 59789 R-XTR-8936584 https://reactome.org/PathwayBrowser/#/R-XTR-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Xenopus tropicalis 59789 R-XTR-8936608 https://reactome.org/PathwayBrowser/#/R-XTR-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Xenopus tropicalis 59789 R-XTR-8936621 https://reactome.org/PathwayBrowser/#/R-XTR-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Xenopus tropicalis 59789 R-XTR-8937016 https://reactome.org/PathwayBrowser/#/R-XTR-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Xenopus tropicalis 59789 R-XTR-8937022 https://reactome.org/PathwayBrowser/#/R-XTR-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Xenopus tropicalis 59789 R-XTR-8937050 https://reactome.org/PathwayBrowser/#/R-XTR-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Xenopus tropicalis 59789 R-XTR-8937113 https://reactome.org/PathwayBrowser/#/R-XTR-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Xenopus tropicalis 59789 R-XTR-947535 https://reactome.org/PathwayBrowser/#/R-XTR-947535 Cyclisation of GTP to precursor Z IEA Xenopus tropicalis 59789 R-XTR-9632182 https://reactome.org/PathwayBrowser/#/R-XTR-9632182 PRMT1 methylates ESRs IEA Xenopus tropicalis 59789 R-XTR-9748979 https://reactome.org/PathwayBrowser/#/R-XTR-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Xenopus tropicalis 59789 R-XTR-9748983 https://reactome.org/PathwayBrowser/#/R-XTR-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Xenopus tropicalis 59869 R-BTA-1236954 https://reactome.org/PathwayBrowser/#/R-BTA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Bos taurus 59869 R-BTA-1236970 https://reactome.org/PathwayBrowser/#/R-BTA-1236970 Proteasomal clevage of exogenous antigen IEA Bos taurus 59869 R-BTA-983150 https://reactome.org/PathwayBrowser/#/R-BTA-983150 Proteasomal cleavage of substrate IEA Bos taurus 59869 R-BTA-983158 https://reactome.org/PathwayBrowser/#/R-BTA-983158 Trimming of peptides in ER IEA Bos taurus 59869 R-BTA-983162 https://reactome.org/PathwayBrowser/#/R-BTA-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Bos taurus 59869 R-CEL-1236970 https://reactome.org/PathwayBrowser/#/R-CEL-1236970 Proteasomal clevage of exogenous antigen IEA Caenorhabditis elegans 59869 R-CEL-983150 https://reactome.org/PathwayBrowser/#/R-CEL-983150 Proteasomal cleavage of substrate IEA Caenorhabditis elegans 59869 R-CEL-983158 https://reactome.org/PathwayBrowser/#/R-CEL-983158 Trimming of peptides in ER IEA Caenorhabditis elegans 59869 R-CEL-983162 https://reactome.org/PathwayBrowser/#/R-CEL-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Caenorhabditis elegans 59869 R-CFA-1236954 https://reactome.org/PathwayBrowser/#/R-CFA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Canis familiaris 59869 R-CFA-1236970 https://reactome.org/PathwayBrowser/#/R-CFA-1236970 Proteasomal clevage of exogenous antigen IEA Canis familiaris 59869 R-CFA-983150 https://reactome.org/PathwayBrowser/#/R-CFA-983150 Proteasomal cleavage of substrate IEA Canis familiaris 59869 R-CFA-983158 https://reactome.org/PathwayBrowser/#/R-CFA-983158 Trimming of peptides in ER IEA Canis familiaris 59869 R-CFA-983162 https://reactome.org/PathwayBrowser/#/R-CFA-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Canis familiaris 59869 R-DDI-1236970 https://reactome.org/PathwayBrowser/#/R-DDI-1236970 Proteasomal clevage of exogenous antigen IEA Dictyostelium discoideum 59869 R-DDI-983150 https://reactome.org/PathwayBrowser/#/R-DDI-983150 Proteasomal cleavage of substrate IEA Dictyostelium discoideum 59869 R-DDI-983158 https://reactome.org/PathwayBrowser/#/R-DDI-983158 Trimming of peptides in ER IEA Dictyostelium discoideum 59869 R-DDI-983162 https://reactome.org/PathwayBrowser/#/R-DDI-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Dictyostelium discoideum 59869 R-DME-1236970 https://reactome.org/PathwayBrowser/#/R-DME-1236970 Proteasomal clevage of exogenous antigen IEA Drosophila melanogaster 59869 R-DME-983150 https://reactome.org/PathwayBrowser/#/R-DME-983150 Proteasomal cleavage of substrate IEA Drosophila melanogaster 59869 R-DME-983158 https://reactome.org/PathwayBrowser/#/R-DME-983158 Trimming of peptides in ER IEA Drosophila melanogaster 59869 R-DME-983162 https://reactome.org/PathwayBrowser/#/R-DME-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Drosophila melanogaster 59869 R-DRE-1236970 https://reactome.org/PathwayBrowser/#/R-DRE-1236970 Proteasomal clevage of exogenous antigen IEA Danio rerio 59869 R-DRE-983150 https://reactome.org/PathwayBrowser/#/R-DRE-983150 Proteasomal cleavage of substrate IEA Danio rerio 59869 R-DRE-983162 https://reactome.org/PathwayBrowser/#/R-DRE-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Danio rerio 59869 R-GGA-1236954 https://reactome.org/PathwayBrowser/#/R-GGA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Gallus gallus 59869 R-GGA-983158 https://reactome.org/PathwayBrowser/#/R-GGA-983158 Trimming of peptides in ER IEA Gallus gallus 59869 R-GGA-983162 https://reactome.org/PathwayBrowser/#/R-GGA-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Gallus gallus 59869 R-HSA-1222712 https://reactome.org/PathwayBrowser/#/R-HSA-1222712 Nitrosoglutathione gets cleaved to Cys(NO)-Gly TAS Homo sapiens 59869 R-HSA-1236935 https://reactome.org/PathwayBrowser/#/R-HSA-1236935 Proteasomal cleavage of substrate IEA Homo sapiens 59869 R-HSA-1236948 https://reactome.org/PathwayBrowser/#/R-HSA-1236948 Antigen processing by cathepsin S in endosoytic vesicle IEA Homo sapiens 59869 R-HSA-1236954 https://reactome.org/PathwayBrowser/#/R-HSA-1236954 Trimming of peptides by IRAP in endocytic vesicles TAS Homo sapiens 59869 R-HSA-1236970 https://reactome.org/PathwayBrowser/#/R-HSA-1236970 Proteasomal clevage of exogenous antigen TAS Homo sapiens 59869 R-HSA-1237102 https://reactome.org/PathwayBrowser/#/R-HSA-1237102 Transamination of MOB to methionine IEA Homo sapiens 59869 R-HSA-983150 https://reactome.org/PathwayBrowser/#/R-HSA-983150 Proteasomal cleavage of substrate TAS Homo sapiens 59869 R-HSA-983158 https://reactome.org/PathwayBrowser/#/R-HSA-983158 Trimming of peptides in ER TAS Homo sapiens 59869 R-HSA-983162 https://reactome.org/PathwayBrowser/#/R-HSA-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases TAS Homo sapiens 59869 R-MMU-1236954 https://reactome.org/PathwayBrowser/#/R-MMU-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Mus musculus 59869 R-MMU-1236970 https://reactome.org/PathwayBrowser/#/R-MMU-1236970 Proteasomal clevage of exogenous antigen IEA Mus musculus 59869 R-MMU-983150 https://reactome.org/PathwayBrowser/#/R-MMU-983150 Proteasomal cleavage of substrate IEA Mus musculus 59869 R-MMU-983158 https://reactome.org/PathwayBrowser/#/R-MMU-983158 Trimming of peptides in ER IEA Mus musculus 59869 R-MMU-983162 https://reactome.org/PathwayBrowser/#/R-MMU-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Mus musculus 59869 R-NUL-1236945 https://reactome.org/PathwayBrowser/#/R-NUL-1236945 Proteasomal cleavage of ovalbumin (OVA) TAS Gallus gallus 59869 R-NUL-1236960 https://reactome.org/PathwayBrowser/#/R-NUL-1236960 Processing of ovalbumin by cathepsin S TAS Gallus gallus 59869 R-PFA-1236970 https://reactome.org/PathwayBrowser/#/R-PFA-1236970 Proteasomal clevage of exogenous antigen IEA Plasmodium falciparum 59869 R-PFA-983150 https://reactome.org/PathwayBrowser/#/R-PFA-983150 Proteasomal cleavage of substrate IEA Plasmodium falciparum 59869 R-RNO-1236954 https://reactome.org/PathwayBrowser/#/R-RNO-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Rattus norvegicus 59869 R-RNO-1236970 https://reactome.org/PathwayBrowser/#/R-RNO-1236970 Proteasomal clevage of exogenous antigen IEA Rattus norvegicus 59869 R-RNO-983150 https://reactome.org/PathwayBrowser/#/R-RNO-983150 Proteasomal cleavage of substrate IEA Rattus norvegicus 59869 R-RNO-983158 https://reactome.org/PathwayBrowser/#/R-RNO-983158 Trimming of peptides in ER IEA Rattus norvegicus 59869 R-RNO-983162 https://reactome.org/PathwayBrowser/#/R-RNO-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Rattus norvegicus 59869 R-SCE-1236970 https://reactome.org/PathwayBrowser/#/R-SCE-1236970 Proteasomal clevage of exogenous antigen IEA Saccharomyces cerevisiae 59869 R-SCE-983150 https://reactome.org/PathwayBrowser/#/R-SCE-983150 Proteasomal cleavage of substrate IEA Saccharomyces cerevisiae 59869 R-SCE-983162 https://reactome.org/PathwayBrowser/#/R-SCE-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Saccharomyces cerevisiae 59869 R-SPO-1236970 https://reactome.org/PathwayBrowser/#/R-SPO-1236970 Proteasomal clevage of exogenous antigen IEA Schizosaccharomyces pombe 59869 R-SPO-983150 https://reactome.org/PathwayBrowser/#/R-SPO-983150 Proteasomal cleavage of substrate IEA Schizosaccharomyces pombe 59869 R-SPO-983162 https://reactome.org/PathwayBrowser/#/R-SPO-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Schizosaccharomyces pombe 59869 R-SSC-1236954 https://reactome.org/PathwayBrowser/#/R-SSC-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Sus scrofa 59869 R-SSC-1236970 https://reactome.org/PathwayBrowser/#/R-SSC-1236970 Proteasomal clevage of exogenous antigen IEA Sus scrofa 59869 R-SSC-983150 https://reactome.org/PathwayBrowser/#/R-SSC-983150 Proteasomal cleavage of substrate IEA Sus scrofa 59869 R-SSC-983158 https://reactome.org/PathwayBrowser/#/R-SSC-983158 Trimming of peptides in ER IEA Sus scrofa 59869 R-SSC-983162 https://reactome.org/PathwayBrowser/#/R-SSC-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Sus scrofa 59869 R-XTR-983158 https://reactome.org/PathwayBrowser/#/R-XTR-983158 Trimming of peptides in ER IEA Xenopus tropicalis 59869 R-XTR-983162 https://reactome.org/PathwayBrowser/#/R-XTR-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Xenopus tropicalis 59888 R-BTA-1013012 https://reactome.org/PathwayBrowser/#/R-BTA-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Bos taurus 59888 R-BTA-1013013 https://reactome.org/PathwayBrowser/#/R-BTA-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Bos taurus 59888 R-BTA-1013020 https://reactome.org/PathwayBrowser/#/R-BTA-1013020 Activation of GIRK/Kir3 Channels IEA Bos taurus 59888 R-BTA-352029 https://reactome.org/PathwayBrowser/#/R-BTA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Bos taurus 59888 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 59888 R-BTA-420688 https://reactome.org/PathwayBrowser/#/R-BTA-420688 GABAB heterodimeric receptor binds GABA IEA Bos taurus 59888 R-BTA-428625 https://reactome.org/PathwayBrowser/#/R-BTA-428625 Vesicular inhibitory amino acid transport IEA Bos taurus 59888 R-BTA-444007 https://reactome.org/PathwayBrowser/#/R-BTA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Bos taurus 59888 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 59888 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 59888 R-BTA-888572 https://reactome.org/PathwayBrowser/#/R-BTA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Bos taurus 59888 R-BTA-888577 https://reactome.org/PathwayBrowser/#/R-BTA-888577 Synthesis of GABA by GAD2 IEA Bos taurus 59888 R-BTA-888589 https://reactome.org/PathwayBrowser/#/R-BTA-888589 Release of GABA at the synapse IEA Bos taurus 59888 R-BTA-888592 https://reactome.org/PathwayBrowser/#/R-BTA-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen IEA Bos taurus 59888 R-BTA-916855 https://reactome.org/PathwayBrowser/#/R-BTA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Bos taurus 59888 R-BTA-917744 https://reactome.org/PathwayBrowser/#/R-BTA-917744 GABA loaded synaptic vesicle Docking and Priming IEA Bos taurus 59888 R-BTA-975340 https://reactome.org/PathwayBrowser/#/R-BTA-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Bos taurus 59888 R-BTA-975449 https://reactome.org/PathwayBrowser/#/R-BTA-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Bos taurus 59888 R-CEL-1013012 https://reactome.org/PathwayBrowser/#/R-CEL-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Caenorhabditis elegans 59888 R-CEL-1013013 https://reactome.org/PathwayBrowser/#/R-CEL-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Caenorhabditis elegans 59888 R-CEL-1013020 https://reactome.org/PathwayBrowser/#/R-CEL-1013020 Activation of GIRK/Kir3 Channels IEA Caenorhabditis elegans 59888 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 59888 R-CEL-420688 https://reactome.org/PathwayBrowser/#/R-CEL-420688 GABAB heterodimeric receptor binds GABA IEA Caenorhabditis elegans 59888 R-CEL-428625 https://reactome.org/PathwayBrowser/#/R-CEL-428625 Vesicular inhibitory amino acid transport IEA Caenorhabditis elegans 59888 R-CEL-444007 https://reactome.org/PathwayBrowser/#/R-CEL-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Caenorhabditis elegans 59888 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 59888 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 59888 R-CEL-888572 https://reactome.org/PathwayBrowser/#/R-CEL-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Caenorhabditis elegans 59888 R-CEL-888577 https://reactome.org/PathwayBrowser/#/R-CEL-888577 Synthesis of GABA by GAD2 IEA Caenorhabditis elegans 59888 R-CEL-888589 https://reactome.org/PathwayBrowser/#/R-CEL-888589 Release of GABA at the synapse IEA Caenorhabditis elegans 59888 R-CEL-888592 https://reactome.org/PathwayBrowser/#/R-CEL-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen IEA Caenorhabditis elegans 59888 R-CEL-916855 https://reactome.org/PathwayBrowser/#/R-CEL-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Caenorhabditis elegans 59888 R-CEL-917744 https://reactome.org/PathwayBrowser/#/R-CEL-917744 GABA loaded synaptic vesicle Docking and Priming IEA Caenorhabditis elegans 59888 R-CEL-975340 https://reactome.org/PathwayBrowser/#/R-CEL-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Caenorhabditis elegans 59888 R-CEL-975449 https://reactome.org/PathwayBrowser/#/R-CEL-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Caenorhabditis elegans 59888 R-CFA-1013012 https://reactome.org/PathwayBrowser/#/R-CFA-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Canis familiaris 59888 R-CFA-1013013 https://reactome.org/PathwayBrowser/#/R-CFA-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Canis familiaris 59888 R-CFA-1013020 https://reactome.org/PathwayBrowser/#/R-CFA-1013020 Activation of GIRK/Kir3 Channels IEA Canis familiaris 59888 R-CFA-352029 https://reactome.org/PathwayBrowser/#/R-CFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Canis familiaris 59888 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 59888 R-CFA-420688 https://reactome.org/PathwayBrowser/#/R-CFA-420688 GABAB heterodimeric receptor binds GABA IEA Canis familiaris 59888 R-CFA-428625 https://reactome.org/PathwayBrowser/#/R-CFA-428625 Vesicular inhibitory amino acid transport IEA Canis familiaris 59888 R-CFA-444007 https://reactome.org/PathwayBrowser/#/R-CFA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Canis familiaris 59888 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 59888 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 59888 R-CFA-888572 https://reactome.org/PathwayBrowser/#/R-CFA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Canis familiaris 59888 R-CFA-888577 https://reactome.org/PathwayBrowser/#/R-CFA-888577 Synthesis of GABA by GAD2 IEA Canis familiaris 59888 R-CFA-888589 https://reactome.org/PathwayBrowser/#/R-CFA-888589 Release of GABA at the synapse IEA Canis familiaris 59888 R-CFA-888592 https://reactome.org/PathwayBrowser/#/R-CFA-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen IEA Canis familiaris 59888 R-CFA-916855 https://reactome.org/PathwayBrowser/#/R-CFA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Canis familiaris 59888 R-CFA-917744 https://reactome.org/PathwayBrowser/#/R-CFA-917744 GABA loaded synaptic vesicle Docking and Priming IEA Canis familiaris 59888 R-CFA-975340 https://reactome.org/PathwayBrowser/#/R-CFA-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Canis familiaris 59888 R-CFA-975449 https://reactome.org/PathwayBrowser/#/R-CFA-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Canis familiaris 59888 R-DDI-380073 https://reactome.org/PathwayBrowser/#/R-DDI-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Dictyostelium discoideum 59888 R-DDI-420688 https://reactome.org/PathwayBrowser/#/R-DDI-420688 GABAB heterodimeric receptor binds GABA IEA Dictyostelium discoideum 59888 R-DDI-916855 https://reactome.org/PathwayBrowser/#/R-DDI-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Dictyostelium discoideum 59888 R-DME-1013012 https://reactome.org/PathwayBrowser/#/R-DME-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Drosophila melanogaster 59888 R-DME-1013013 https://reactome.org/PathwayBrowser/#/R-DME-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Drosophila melanogaster 59888 R-DME-1013020 https://reactome.org/PathwayBrowser/#/R-DME-1013020 Activation of GIRK/Kir3 Channels IEA Drosophila melanogaster 59888 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 59888 R-DME-420688 https://reactome.org/PathwayBrowser/#/R-DME-420688 GABAB heterodimeric receptor binds GABA IEA Drosophila melanogaster 59888 R-DME-428625 https://reactome.org/PathwayBrowser/#/R-DME-428625 Vesicular inhibitory amino acid transport IEA Drosophila melanogaster 59888 R-DME-444007 https://reactome.org/PathwayBrowser/#/R-DME-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Drosophila melanogaster 59888 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 59888 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 59888 R-DME-888572 https://reactome.org/PathwayBrowser/#/R-DME-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Drosophila melanogaster 59888 R-DME-888577 https://reactome.org/PathwayBrowser/#/R-DME-888577 Synthesis of GABA by GAD2 IEA Drosophila melanogaster 59888 R-DME-888589 https://reactome.org/PathwayBrowser/#/R-DME-888589 Release of GABA at the synapse IEA Drosophila melanogaster 59888 R-DME-888592 https://reactome.org/PathwayBrowser/#/R-DME-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen IEA Drosophila melanogaster 59888 R-DME-916855 https://reactome.org/PathwayBrowser/#/R-DME-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Drosophila melanogaster 59888 R-DME-917744 https://reactome.org/PathwayBrowser/#/R-DME-917744 GABA loaded synaptic vesicle Docking and Priming IEA Drosophila melanogaster 59888 R-DME-975340 https://reactome.org/PathwayBrowser/#/R-DME-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Drosophila melanogaster 59888 R-DME-975449 https://reactome.org/PathwayBrowser/#/R-DME-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Drosophila melanogaster 59888 R-DRE-352029 https://reactome.org/PathwayBrowser/#/R-DRE-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Danio rerio 59888 R-DRE-428625 https://reactome.org/PathwayBrowser/#/R-DRE-428625 Vesicular inhibitory amino acid transport IEA Danio rerio 59888 R-DRE-444007 https://reactome.org/PathwayBrowser/#/R-DRE-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Danio rerio 59888 R-DRE-888572 https://reactome.org/PathwayBrowser/#/R-DRE-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Danio rerio 59888 R-DRE-888592 https://reactome.org/PathwayBrowser/#/R-DRE-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen IEA Danio rerio 59888 R-DRE-916855 https://reactome.org/PathwayBrowser/#/R-DRE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Danio rerio 59888 R-DRE-975449 https://reactome.org/PathwayBrowser/#/R-DRE-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Danio rerio 59888 R-GGA-1013012 https://reactome.org/PathwayBrowser/#/R-GGA-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Gallus gallus 59888 R-GGA-1013013 https://reactome.org/PathwayBrowser/#/R-GGA-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Gallus gallus 59888 R-GGA-1013020 https://reactome.org/PathwayBrowser/#/R-GGA-1013020 Activation of GIRK/Kir3 Channels IEA Gallus gallus 59888 R-GGA-352029 https://reactome.org/PathwayBrowser/#/R-GGA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Gallus gallus 59888 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 59888 R-GGA-420688 https://reactome.org/PathwayBrowser/#/R-GGA-420688 GABAB heterodimeric receptor binds GABA IEA Gallus gallus 59888 R-GGA-428625 https://reactome.org/PathwayBrowser/#/R-GGA-428625 Vesicular inhibitory amino acid transport IEA Gallus gallus 59888 R-GGA-444007 https://reactome.org/PathwayBrowser/#/R-GGA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Gallus gallus 59888 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 59888 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 59888 R-GGA-888572 https://reactome.org/PathwayBrowser/#/R-GGA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Gallus gallus 59888 R-GGA-888577 https://reactome.org/PathwayBrowser/#/R-GGA-888577 Synthesis of GABA by GAD2 IEA Gallus gallus 59888 R-GGA-888592 https://reactome.org/PathwayBrowser/#/R-GGA-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen IEA Gallus gallus 59888 R-GGA-916855 https://reactome.org/PathwayBrowser/#/R-GGA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Gallus gallus 59888 R-GGA-975340 https://reactome.org/PathwayBrowser/#/R-GGA-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Gallus gallus 59888 R-GGA-975449 https://reactome.org/PathwayBrowser/#/R-GGA-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Gallus gallus 59888 R-HSA-1013012 https://reactome.org/PathwayBrowser/#/R-HSA-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels TAS Homo sapiens 59888 R-HSA-1013013 https://reactome.org/PathwayBrowser/#/R-HSA-1013013 Association of GABA B receptor with G protein beta-gamma subunits TAS Homo sapiens 59888 R-HSA-1013020 https://reactome.org/PathwayBrowser/#/R-HSA-1013020 Activation of GIRK/Kir3 Channels TAS Homo sapiens 59888 R-HSA-352029 https://reactome.org/PathwayBrowser/#/R-HSA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine TAS Homo sapiens 59888 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 59888 R-HSA-420688 https://reactome.org/PathwayBrowser/#/R-HSA-420688 GABAB heterodimeric receptor binds GABA TAS Homo sapiens 59888 R-HSA-428625 https://reactome.org/PathwayBrowser/#/R-HSA-428625 Vesicular inhibitory amino acid transport TAS Homo sapiens 59888 R-HSA-444007 https://reactome.org/PathwayBrowser/#/R-HSA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport TAS Homo sapiens 59888 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 59888 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 59888 R-HSA-8856398 https://reactome.org/PathwayBrowser/#/R-HSA-8856398 NPTN binds GABA A receptors IEA Homo sapiens 59888 R-HSA-888572 https://reactome.org/PathwayBrowser/#/R-HSA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA TAS Homo sapiens 59888 R-HSA-888577 https://reactome.org/PathwayBrowser/#/R-HSA-888577 Synthesis of GABA by GAD2 TAS Homo sapiens 59888 R-HSA-888589 https://reactome.org/PathwayBrowser/#/R-HSA-888589 Release of GABA at the synapse TAS Homo sapiens 59888 R-HSA-888592 https://reactome.org/PathwayBrowser/#/R-HSA-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen TAS Homo sapiens 59888 R-HSA-916855 https://reactome.org/PathwayBrowser/#/R-HSA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA TAS Homo sapiens 59888 R-HSA-917744 https://reactome.org/PathwayBrowser/#/R-HSA-917744 GABA loaded synaptic vesicle Docking and Priming TAS Homo sapiens 59888 R-HSA-9612639 https://reactome.org/PathwayBrowser/#/R-HSA-9612639 NRG2-activated ERBB4 binds GABA receptors through GABRA1 IEA Homo sapiens 59888 R-HSA-9653180 https://reactome.org/PathwayBrowser/#/R-HSA-9653180 GABA translocates from cytosol to mitochondrial matrix TAS Homo sapiens 59888 R-HSA-975340 https://reactome.org/PathwayBrowser/#/R-HSA-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol TAS Homo sapiens 59888 R-HSA-975449 https://reactome.org/PathwayBrowser/#/R-HSA-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol TAS Homo sapiens 59888 R-MMU-1013012 https://reactome.org/PathwayBrowser/#/R-MMU-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Mus musculus 59888 R-MMU-1013013 https://reactome.org/PathwayBrowser/#/R-MMU-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Mus musculus 59888 R-MMU-1013020 https://reactome.org/PathwayBrowser/#/R-MMU-1013020 Activation of GIRK/Kir3 Channels IEA Mus musculus 59888 R-MMU-352029 https://reactome.org/PathwayBrowser/#/R-MMU-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Mus musculus 59888 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 59888 R-MMU-420688 https://reactome.org/PathwayBrowser/#/R-MMU-420688 GABAB heterodimeric receptor binds GABA IEA Mus musculus 59888 R-MMU-428625 https://reactome.org/PathwayBrowser/#/R-MMU-428625 Vesicular inhibitory amino acid transport IEA Mus musculus 59888 R-MMU-444007 https://reactome.org/PathwayBrowser/#/R-MMU-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Mus musculus 59888 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 59888 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 59888 R-MMU-888572 https://reactome.org/PathwayBrowser/#/R-MMU-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Mus musculus 59888 R-MMU-888577 https://reactome.org/PathwayBrowser/#/R-MMU-888577 Synthesis of GABA by GAD2 IEA Mus musculus 59888 R-MMU-888589 https://reactome.org/PathwayBrowser/#/R-MMU-888589 Release of GABA at the synapse IEA Mus musculus 59888 R-MMU-888592 https://reactome.org/PathwayBrowser/#/R-MMU-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen IEA Mus musculus 59888 R-MMU-916855 https://reactome.org/PathwayBrowser/#/R-MMU-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Mus musculus 59888 R-MMU-917744 https://reactome.org/PathwayBrowser/#/R-MMU-917744 GABA loaded synaptic vesicle Docking and Priming IEA Mus musculus 59888 R-MMU-975340 https://reactome.org/PathwayBrowser/#/R-MMU-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Mus musculus 59888 R-MMU-975449 https://reactome.org/PathwayBrowser/#/R-MMU-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Mus musculus 59888 R-NUL-9612654 https://reactome.org/PathwayBrowser/#/R-NUL-9612654 Nrg2-activated Erbb4 binds GABA receptors through Gabra1 TAS Mus musculus 59888 R-PFA-352029 https://reactome.org/PathwayBrowser/#/R-PFA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Plasmodium falciparum 59888 R-PFA-444007 https://reactome.org/PathwayBrowser/#/R-PFA-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Plasmodium falciparum 59888 R-RNO-1013012 https://reactome.org/PathwayBrowser/#/R-RNO-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Rattus norvegicus 59888 R-RNO-1013020 https://reactome.org/PathwayBrowser/#/R-RNO-1013020 Activation of GIRK/Kir3 Channels IEA Rattus norvegicus 59888 R-RNO-352029 https://reactome.org/PathwayBrowser/#/R-RNO-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Rattus norvegicus 59888 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 59888 R-RNO-420688 https://reactome.org/PathwayBrowser/#/R-RNO-420688 GABAB heterodimeric receptor binds GABA IEA Rattus norvegicus 59888 R-RNO-428625 https://reactome.org/PathwayBrowser/#/R-RNO-428625 Vesicular inhibitory amino acid transport IEA Rattus norvegicus 59888 R-RNO-444007 https://reactome.org/PathwayBrowser/#/R-RNO-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Rattus norvegicus 59888 R-RNO-8856390 https://reactome.org/PathwayBrowser/#/R-RNO-8856390 Nptn binds 2xGabra1,2xGabrb2,Gabrg2:GABA TAS Rattus norvegicus 59888 R-RNO-888572 https://reactome.org/PathwayBrowser/#/R-RNO-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Rattus norvegicus 59888 R-RNO-888577 https://reactome.org/PathwayBrowser/#/R-RNO-888577 Synthesis of GABA by GAD2 IEA Rattus norvegicus 59888 R-RNO-888589 https://reactome.org/PathwayBrowser/#/R-RNO-888589 Release of GABA at the synapse IEA Rattus norvegicus 59888 R-RNO-888592 https://reactome.org/PathwayBrowser/#/R-RNO-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen IEA Rattus norvegicus 59888 R-RNO-916855 https://reactome.org/PathwayBrowser/#/R-RNO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Rattus norvegicus 59888 R-RNO-917744 https://reactome.org/PathwayBrowser/#/R-RNO-917744 GABA loaded synaptic vesicle Docking and Priming IEA Rattus norvegicus 59888 R-RNO-975340 https://reactome.org/PathwayBrowser/#/R-RNO-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Rattus norvegicus 59888 R-RNO-975449 https://reactome.org/PathwayBrowser/#/R-RNO-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Rattus norvegicus 59888 R-SCE-428625 https://reactome.org/PathwayBrowser/#/R-SCE-428625 Vesicular inhibitory amino acid transport IEA Saccharomyces cerevisiae 59888 R-SCE-888592 https://reactome.org/PathwayBrowser/#/R-SCE-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen IEA Saccharomyces cerevisiae 59888 R-SCE-916855 https://reactome.org/PathwayBrowser/#/R-SCE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Saccharomyces cerevisiae 59888 R-SPO-916855 https://reactome.org/PathwayBrowser/#/R-SPO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Schizosaccharomyces pombe 59888 R-SSC-1013012 https://reactome.org/PathwayBrowser/#/R-SSC-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Sus scrofa 59888 R-SSC-1013013 https://reactome.org/PathwayBrowser/#/R-SSC-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Sus scrofa 59888 R-SSC-1013020 https://reactome.org/PathwayBrowser/#/R-SSC-1013020 Activation of GIRK/Kir3 Channels IEA Sus scrofa 59888 R-SSC-352029 https://reactome.org/PathwayBrowser/#/R-SSC-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Sus scrofa 59888 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 59888 R-SSC-420688 https://reactome.org/PathwayBrowser/#/R-SSC-420688 GABAB heterodimeric receptor binds GABA IEA Sus scrofa 59888 R-SSC-428625 https://reactome.org/PathwayBrowser/#/R-SSC-428625 Vesicular inhibitory amino acid transport IEA Sus scrofa 59888 R-SSC-444007 https://reactome.org/PathwayBrowser/#/R-SSC-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Sus scrofa 59888 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 59888 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 59888 R-SSC-888572 https://reactome.org/PathwayBrowser/#/R-SSC-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Sus scrofa 59888 R-SSC-888577 https://reactome.org/PathwayBrowser/#/R-SSC-888577 Synthesis of GABA by GAD2 IEA Sus scrofa 59888 R-SSC-888589 https://reactome.org/PathwayBrowser/#/R-SSC-888589 Release of GABA at the synapse IEA Sus scrofa 59888 R-SSC-888592 https://reactome.org/PathwayBrowser/#/R-SSC-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen IEA Sus scrofa 59888 R-SSC-916855 https://reactome.org/PathwayBrowser/#/R-SSC-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Sus scrofa 59888 R-SSC-917744 https://reactome.org/PathwayBrowser/#/R-SSC-917744 GABA loaded synaptic vesicle Docking and Priming IEA Sus scrofa 59888 R-SSC-975340 https://reactome.org/PathwayBrowser/#/R-SSC-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Sus scrofa 59888 R-SSC-975449 https://reactome.org/PathwayBrowser/#/R-SSC-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Sus scrofa 59888 R-XTR-1013020 https://reactome.org/PathwayBrowser/#/R-XTR-1013020 Activation of GIRK/Kir3 Channels IEA Xenopus tropicalis 59888 R-XTR-352029 https://reactome.org/PathwayBrowser/#/R-XTR-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Xenopus tropicalis 59888 R-XTR-444007 https://reactome.org/PathwayBrowser/#/R-XTR-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Xenopus tropicalis 59888 R-XTR-888572 https://reactome.org/PathwayBrowser/#/R-XTR-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Xenopus tropicalis 59888 R-XTR-888577 https://reactome.org/PathwayBrowser/#/R-XTR-888577 Synthesis of GABA by GAD2 IEA Xenopus tropicalis 59888 R-XTR-916855 https://reactome.org/PathwayBrowser/#/R-XTR-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Xenopus tropicalis 59888 R-XTR-917744 https://reactome.org/PathwayBrowser/#/R-XTR-917744 GABA loaded synaptic vesicle Docking and Priming IEA Xenopus tropicalis 59888 R-XTR-975340 https://reactome.org/PathwayBrowser/#/R-XTR-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Xenopus tropicalis 59888 R-XTR-975449 https://reactome.org/PathwayBrowser/#/R-XTR-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Xenopus tropicalis 59905 R-BTA-159358 https://reactome.org/PathwayBrowser/#/R-BTA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Bos taurus 59905 R-BTA-209891 https://reactome.org/PathwayBrowser/#/R-BTA-209891 Dopamine is oxidised to noradrenaline IEA Bos taurus 59905 R-BTA-209924 https://reactome.org/PathwayBrowser/#/R-BTA-209924 Dopa is decarboxylated to dopamine IEA Bos taurus 59905 R-BTA-372542 https://reactome.org/PathwayBrowser/#/R-BTA-372542 Loading of dopamine into synaptic veiscles IEA Bos taurus 59905 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 59905 R-BTA-379382 https://reactome.org/PathwayBrowser/#/R-BTA-379382 MAOA:FAD deaminates DA to DOPAC IEA Bos taurus 59905 R-BTA-379387 https://reactome.org/PathwayBrowser/#/R-BTA-379387 COMT transfers Met to DA to form 3MT IEA Bos taurus 59905 R-BTA-379393 https://reactome.org/PathwayBrowser/#/R-BTA-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Bos taurus 59905 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 59905 R-BTA-380574 https://reactome.org/PathwayBrowser/#/R-BTA-380574 Dopamine synaptic vesicle docking and priming IEA Bos taurus 59905 R-BTA-380869 https://reactome.org/PathwayBrowser/#/R-BTA-380869 Release of docked dopamine loaded synaptic vesicle IEA Bos taurus 59905 R-BTA-390835 https://reactome.org/PathwayBrowser/#/R-BTA-390835 DRD1,5 bind DA IEA Bos taurus 59905 R-BTA-390846 https://reactome.org/PathwayBrowser/#/R-BTA-390846 D2D3,4 bind to DA IEA Bos taurus 59905 R-BTA-444160 https://reactome.org/PathwayBrowser/#/R-BTA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Bos taurus 59905 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 59905 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 59905 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 59905 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 59905 R-BTA-727740 https://reactome.org/PathwayBrowser/#/R-BTA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 59905 R-BTA-727768 https://reactome.org/PathwayBrowser/#/R-BTA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 59905 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 59905 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 59905 R-BTA-8955010 https://reactome.org/PathwayBrowser/#/R-BTA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Bos taurus 59905 R-BTA-9656244 https://reactome.org/PathwayBrowser/#/R-BTA-9656244 DRD2 binds DA IEA Bos taurus 59905 R-CEL-209924 https://reactome.org/PathwayBrowser/#/R-CEL-209924 Dopa is decarboxylated to dopamine IEA Caenorhabditis elegans 59905 R-CEL-372542 https://reactome.org/PathwayBrowser/#/R-CEL-372542 Loading of dopamine into synaptic veiscles IEA Caenorhabditis elegans 59905 R-CEL-379393 https://reactome.org/PathwayBrowser/#/R-CEL-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 59905 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 59905 R-CEL-380574 https://reactome.org/PathwayBrowser/#/R-CEL-380574 Dopamine synaptic vesicle docking and priming IEA Caenorhabditis elegans 59905 R-CEL-380869 https://reactome.org/PathwayBrowser/#/R-CEL-380869 Release of docked dopamine loaded synaptic vesicle IEA Caenorhabditis elegans 59905 R-CEL-390846 https://reactome.org/PathwayBrowser/#/R-CEL-390846 D2D3,4 bind to DA IEA Caenorhabditis elegans 59905 R-CEL-444160 https://reactome.org/PathwayBrowser/#/R-CEL-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Caenorhabditis elegans 59905 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 59905 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 59905 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 59905 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 59905 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 59905 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 59905 R-CEL-9656244 https://reactome.org/PathwayBrowser/#/R-CEL-9656244 DRD2 binds DA IEA Caenorhabditis elegans 59905 R-CFA-159358 https://reactome.org/PathwayBrowser/#/R-CFA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Canis familiaris 59905 R-CFA-209891 https://reactome.org/PathwayBrowser/#/R-CFA-209891 Dopamine is oxidised to noradrenaline IEA Canis familiaris 59905 R-CFA-209924 https://reactome.org/PathwayBrowser/#/R-CFA-209924 Dopa is decarboxylated to dopamine IEA Canis familiaris 59905 R-CFA-372542 https://reactome.org/PathwayBrowser/#/R-CFA-372542 Loading of dopamine into synaptic veiscles IEA Canis familiaris 59905 R-CFA-379382 https://reactome.org/PathwayBrowser/#/R-CFA-379382 MAOA:FAD deaminates DA to DOPAC IEA Canis familiaris 59905 R-CFA-379387 https://reactome.org/PathwayBrowser/#/R-CFA-379387 COMT transfers Met to DA to form 3MT IEA Canis familiaris 59905 R-CFA-379393 https://reactome.org/PathwayBrowser/#/R-CFA-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Canis familiaris 59905 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 59905 R-CFA-380574 https://reactome.org/PathwayBrowser/#/R-CFA-380574 Dopamine synaptic vesicle docking and priming IEA Canis familiaris 59905 R-CFA-380869 https://reactome.org/PathwayBrowser/#/R-CFA-380869 Release of docked dopamine loaded synaptic vesicle IEA Canis familiaris 59905 R-CFA-390835 https://reactome.org/PathwayBrowser/#/R-CFA-390835 DRD1,5 bind DA IEA Canis familiaris 59905 R-CFA-390846 https://reactome.org/PathwayBrowser/#/R-CFA-390846 D2D3,4 bind to DA IEA Canis familiaris 59905 R-CFA-444160 https://reactome.org/PathwayBrowser/#/R-CFA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Canis familiaris 59905 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 59905 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 59905 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 59905 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 59905 R-CFA-727740 https://reactome.org/PathwayBrowser/#/R-CFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 59905 R-CFA-727768 https://reactome.org/PathwayBrowser/#/R-CFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 59905 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 59905 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 59905 R-CFA-8955010 https://reactome.org/PathwayBrowser/#/R-CFA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Canis familiaris 59905 R-CFA-9656244 https://reactome.org/PathwayBrowser/#/R-CFA-9656244 DRD2 binds DA IEA Canis familiaris 59905 R-DDI-379382 https://reactome.org/PathwayBrowser/#/R-DDI-379382 MAOA:FAD deaminates DA to DOPAC IEA Dictyostelium discoideum 59905 R-DDI-727740 https://reactome.org/PathwayBrowser/#/R-DDI-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 59905 R-DDI-727768 https://reactome.org/PathwayBrowser/#/R-DDI-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 59905 R-DME-159358 https://reactome.org/PathwayBrowser/#/R-DME-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Drosophila melanogaster 59905 R-DME-209891 https://reactome.org/PathwayBrowser/#/R-DME-209891 Dopamine is oxidised to noradrenaline IEA Drosophila melanogaster 59905 R-DME-209924 https://reactome.org/PathwayBrowser/#/R-DME-209924 Dopa is decarboxylated to dopamine IEA Drosophila melanogaster 59905 R-DME-372542 https://reactome.org/PathwayBrowser/#/R-DME-372542 Loading of dopamine into synaptic veiscles IEA Drosophila melanogaster 59905 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 59905 R-DME-379393 https://reactome.org/PathwayBrowser/#/R-DME-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 59905 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 59905 R-DME-380574 https://reactome.org/PathwayBrowser/#/R-DME-380574 Dopamine synaptic vesicle docking and priming IEA Drosophila melanogaster 59905 R-DME-380869 https://reactome.org/PathwayBrowser/#/R-DME-380869 Release of docked dopamine loaded synaptic vesicle IEA Drosophila melanogaster 59905 R-DME-390835 https://reactome.org/PathwayBrowser/#/R-DME-390835 DRD1,5 bind DA IEA Drosophila melanogaster 59905 R-DME-390846 https://reactome.org/PathwayBrowser/#/R-DME-390846 D2D3,4 bind to DA IEA Drosophila melanogaster 59905 R-DME-444160 https://reactome.org/PathwayBrowser/#/R-DME-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Drosophila melanogaster 59905 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 59905 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 59905 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 59905 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 59905 R-DME-727740 https://reactome.org/PathwayBrowser/#/R-DME-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 59905 R-DME-727768 https://reactome.org/PathwayBrowser/#/R-DME-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 59905 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 59905 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 59905 R-DME-9656244 https://reactome.org/PathwayBrowser/#/R-DME-9656244 DRD2 binds DA IEA Drosophila melanogaster 59905 R-DRE-159358 https://reactome.org/PathwayBrowser/#/R-DRE-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Danio rerio 59905 R-DRE-209891 https://reactome.org/PathwayBrowser/#/R-DRE-209891 Dopamine is oxidised to noradrenaline IEA Danio rerio 59905 R-DRE-209924 https://reactome.org/PathwayBrowser/#/R-DRE-209924 Dopa is decarboxylated to dopamine IEA Danio rerio 59905 R-DRE-379387 https://reactome.org/PathwayBrowser/#/R-DRE-379387 COMT transfers Met to DA to form 3MT IEA Danio rerio 59905 R-DRE-379393 https://reactome.org/PathwayBrowser/#/R-DRE-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Danio rerio 59905 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 59905 R-DRE-390835 https://reactome.org/PathwayBrowser/#/R-DRE-390835 DRD1,5 bind DA IEA Danio rerio 59905 R-DRE-390846 https://reactome.org/PathwayBrowser/#/R-DRE-390846 D2D3,4 bind to DA IEA Danio rerio 59905 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 59905 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 59905 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 59905 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 59905 R-DRE-727740 https://reactome.org/PathwayBrowser/#/R-DRE-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 59905 R-DRE-727768 https://reactome.org/PathwayBrowser/#/R-DRE-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 59905 R-DRE-8955010 https://reactome.org/PathwayBrowser/#/R-DRE-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Danio rerio 59905 R-DRE-9656244 https://reactome.org/PathwayBrowser/#/R-DRE-9656244 DRD2 binds DA IEA Danio rerio 59905 R-GGA-159358 https://reactome.org/PathwayBrowser/#/R-GGA-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Gallus gallus 59905 R-GGA-209891 https://reactome.org/PathwayBrowser/#/R-GGA-209891 Dopamine is oxidised to noradrenaline IEA Gallus gallus 59905 R-GGA-209924 https://reactome.org/PathwayBrowser/#/R-GGA-209924 Dopa is decarboxylated to dopamine IEA Gallus gallus 59905 R-GGA-372542 https://reactome.org/PathwayBrowser/#/R-GGA-372542 Loading of dopamine into synaptic veiscles IEA Gallus gallus 59905 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 59905 R-GGA-379382 https://reactome.org/PathwayBrowser/#/R-GGA-379382 MAOA:FAD deaminates DA to DOPAC IEA Gallus gallus 59905 R-GGA-379387 https://reactome.org/PathwayBrowser/#/R-GGA-379387 COMT transfers Met to DA to form 3MT IEA Gallus gallus 59905 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 59905 R-GGA-390835 https://reactome.org/PathwayBrowser/#/R-GGA-390835 DRD1,5 bind DA IEA Gallus gallus 59905 R-GGA-390846 https://reactome.org/PathwayBrowser/#/R-GGA-390846 D2D3,4 bind to DA IEA Gallus gallus 59905 R-GGA-444160 https://reactome.org/PathwayBrowser/#/R-GGA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Gallus gallus 59905 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 59905 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 59905 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 59905 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 59905 R-GGA-727740 https://reactome.org/PathwayBrowser/#/R-GGA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 59905 R-GGA-727768 https://reactome.org/PathwayBrowser/#/R-GGA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 59905 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 59905 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 59905 R-GGA-8955010 https://reactome.org/PathwayBrowser/#/R-GGA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Gallus gallus 59905 R-GGA-9656244 https://reactome.org/PathwayBrowser/#/R-GGA-9656244 DRD2 binds DA IEA Gallus gallus 59905 R-HSA-159358 https://reactome.org/PathwayBrowser/#/R-HSA-159358 SULT1A3,4 dimers sulfate DA to DAOS TAS Homo sapiens 59905 R-HSA-209891 https://reactome.org/PathwayBrowser/#/R-HSA-209891 Dopamine is oxidised to noradrenaline TAS Homo sapiens 59905 R-HSA-209924 https://reactome.org/PathwayBrowser/#/R-HSA-209924 Dopa is decarboxylated to dopamine TAS Homo sapiens 59905 R-HSA-351596 https://reactome.org/PathwayBrowser/#/R-HSA-351596 Dopamine translocates to a secretory vesicle TAS Homo sapiens 59905 R-HSA-372542 https://reactome.org/PathwayBrowser/#/R-HSA-372542 Loading of dopamine into synaptic veiscles TAS Homo sapiens 59905 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 59905 R-HSA-379382 https://reactome.org/PathwayBrowser/#/R-HSA-379382 MAOA:FAD deaminates DA to DOPAC TAS Homo sapiens 59905 R-HSA-379387 https://reactome.org/PathwayBrowser/#/R-HSA-379387 COMT transfers Met to DA to form 3MT TAS Homo sapiens 59905 R-HSA-379393 https://reactome.org/PathwayBrowser/#/R-HSA-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol TAS Homo sapiens 59905 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 59905 R-HSA-380574 https://reactome.org/PathwayBrowser/#/R-HSA-380574 Dopamine synaptic vesicle docking and priming TAS Homo sapiens 59905 R-HSA-380869 https://reactome.org/PathwayBrowser/#/R-HSA-380869 Release of docked dopamine loaded synaptic vesicle TAS Homo sapiens 59905 R-HSA-390835 https://reactome.org/PathwayBrowser/#/R-HSA-390835 DRD1,5 bind DA TAS Homo sapiens 59905 R-HSA-390846 https://reactome.org/PathwayBrowser/#/R-HSA-390846 D2D3,4 bind to DA TAS Homo sapiens 59905 R-HSA-444160 https://reactome.org/PathwayBrowser/#/R-HSA-444160 VMAT1/2 can mediate the transport of biogenic amines TAS Homo sapiens 59905 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 59905 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 59905 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 59905 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 59905 R-HSA-5660706 https://reactome.org/PathwayBrowser/#/R-HSA-5660706 Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol TAS Homo sapiens 59905 R-HSA-727740 https://reactome.org/PathwayBrowser/#/R-HSA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 59905 R-HSA-727768 https://reactome.org/PathwayBrowser/#/R-HSA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 59905 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 59905 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 59905 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 59905 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 59905 R-HSA-8955010 https://reactome.org/PathwayBrowser/#/R-HSA-8955010 LRTOMT transfers Met to DA, forming 3MT TAS Homo sapiens 59905 R-HSA-9656244 https://reactome.org/PathwayBrowser/#/R-HSA-9656244 DRD2 binds DA TAS Homo sapiens 59905 R-MMU-159358 https://reactome.org/PathwayBrowser/#/R-MMU-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Mus musculus 59905 R-MMU-209891 https://reactome.org/PathwayBrowser/#/R-MMU-209891 Dopamine is oxidised to noradrenaline IEA Mus musculus 59905 R-MMU-209924 https://reactome.org/PathwayBrowser/#/R-MMU-209924 Dopa is decarboxylated to dopamine IEA Mus musculus 59905 R-MMU-372542 https://reactome.org/PathwayBrowser/#/R-MMU-372542 Loading of dopamine into synaptic veiscles IEA Mus musculus 59905 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 59905 R-MMU-379382 https://reactome.org/PathwayBrowser/#/R-MMU-379382 MAOA:FAD deaminates DA to DOPAC IEA Mus musculus 59905 R-MMU-379387 https://reactome.org/PathwayBrowser/#/R-MMU-379387 COMT transfers Met to DA to form 3MT IEA Mus musculus 59905 R-MMU-379393 https://reactome.org/PathwayBrowser/#/R-MMU-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Mus musculus 59905 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 59905 R-MMU-380574 https://reactome.org/PathwayBrowser/#/R-MMU-380574 Dopamine synaptic vesicle docking and priming IEA Mus musculus 59905 R-MMU-380869 https://reactome.org/PathwayBrowser/#/R-MMU-380869 Release of docked dopamine loaded synaptic vesicle IEA Mus musculus 59905 R-MMU-390835 https://reactome.org/PathwayBrowser/#/R-MMU-390835 DRD1,5 bind DA IEA Mus musculus 59905 R-MMU-390846 https://reactome.org/PathwayBrowser/#/R-MMU-390846 D2D3,4 bind to DA IEA Mus musculus 59905 R-MMU-444160 https://reactome.org/PathwayBrowser/#/R-MMU-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Mus musculus 59905 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 59905 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 59905 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 59905 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 59905 R-MMU-727740 https://reactome.org/PathwayBrowser/#/R-MMU-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 59905 R-MMU-727768 https://reactome.org/PathwayBrowser/#/R-MMU-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 59905 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 59905 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 59905 R-MMU-8955010 https://reactome.org/PathwayBrowser/#/R-MMU-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Mus musculus 59905 R-MMU-9656244 https://reactome.org/PathwayBrowser/#/R-MMU-9656244 DRD2 binds DA IEA Mus musculus 59905 R-PFA-379393 https://reactome.org/PathwayBrowser/#/R-PFA-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 59905 R-PFA-727740 https://reactome.org/PathwayBrowser/#/R-PFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 59905 R-PFA-727768 https://reactome.org/PathwayBrowser/#/R-PFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 59905 R-RNO-159358 https://reactome.org/PathwayBrowser/#/R-RNO-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Rattus norvegicus 59905 R-RNO-209891 https://reactome.org/PathwayBrowser/#/R-RNO-209891 Dopamine is oxidised to noradrenaline IEA Rattus norvegicus 59905 R-RNO-209924 https://reactome.org/PathwayBrowser/#/R-RNO-209924 Dopa is decarboxylated to dopamine IEA Rattus norvegicus 59905 R-RNO-372542 https://reactome.org/PathwayBrowser/#/R-RNO-372542 Loading of dopamine into synaptic veiscles IEA Rattus norvegicus 59905 R-RNO-379382 https://reactome.org/PathwayBrowser/#/R-RNO-379382 MAOA:FAD deaminates DA to DOPAC IEA Rattus norvegicus 59905 R-RNO-379387 https://reactome.org/PathwayBrowser/#/R-RNO-379387 COMT transfers Met to DA to form 3MT IEA Rattus norvegicus 59905 R-RNO-379393 https://reactome.org/PathwayBrowser/#/R-RNO-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Rattus norvegicus 59905 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 59905 R-RNO-380574 https://reactome.org/PathwayBrowser/#/R-RNO-380574 Dopamine synaptic vesicle docking and priming IEA Rattus norvegicus 59905 R-RNO-380869 https://reactome.org/PathwayBrowser/#/R-RNO-380869 Release of docked dopamine loaded synaptic vesicle IEA Rattus norvegicus 59905 R-RNO-390835 https://reactome.org/PathwayBrowser/#/R-RNO-390835 DRD1,5 bind DA IEA Rattus norvegicus 59905 R-RNO-390846 https://reactome.org/PathwayBrowser/#/R-RNO-390846 D2D3,4 bind to DA IEA Rattus norvegicus 59905 R-RNO-444160 https://reactome.org/PathwayBrowser/#/R-RNO-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Rattus norvegicus 59905 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 59905 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 59905 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 59905 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 59905 R-RNO-727740 https://reactome.org/PathwayBrowser/#/R-RNO-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 59905 R-RNO-727768 https://reactome.org/PathwayBrowser/#/R-RNO-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 59905 R-RNO-8955010 https://reactome.org/PathwayBrowser/#/R-RNO-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Rattus norvegicus 59905 R-RNO-9656244 https://reactome.org/PathwayBrowser/#/R-RNO-9656244 DRD2 binds DA IEA Rattus norvegicus 59905 R-SPO-372542 https://reactome.org/PathwayBrowser/#/R-SPO-372542 Loading of dopamine into synaptic veiscles IEA Schizosaccharomyces pombe 59905 R-SPO-379387 https://reactome.org/PathwayBrowser/#/R-SPO-379387 COMT transfers Met to DA to form 3MT IEA Schizosaccharomyces pombe 59905 R-SPO-444160 https://reactome.org/PathwayBrowser/#/R-SPO-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Schizosaccharomyces pombe 59905 R-SPO-8955010 https://reactome.org/PathwayBrowser/#/R-SPO-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Schizosaccharomyces pombe 59905 R-SSC-159358 https://reactome.org/PathwayBrowser/#/R-SSC-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Sus scrofa 59905 R-SSC-209891 https://reactome.org/PathwayBrowser/#/R-SSC-209891 Dopamine is oxidised to noradrenaline IEA Sus scrofa 59905 R-SSC-209924 https://reactome.org/PathwayBrowser/#/R-SSC-209924 Dopa is decarboxylated to dopamine IEA Sus scrofa 59905 R-SSC-372542 https://reactome.org/PathwayBrowser/#/R-SSC-372542 Loading of dopamine into synaptic veiscles IEA Sus scrofa 59905 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 59905 R-SSC-379382 https://reactome.org/PathwayBrowser/#/R-SSC-379382 MAOA:FAD deaminates DA to DOPAC IEA Sus scrofa 59905 R-SSC-379387 https://reactome.org/PathwayBrowser/#/R-SSC-379387 COMT transfers Met to DA to form 3MT IEA Sus scrofa 59905 R-SSC-379393 https://reactome.org/PathwayBrowser/#/R-SSC-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Sus scrofa 59905 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 59905 R-SSC-380574 https://reactome.org/PathwayBrowser/#/R-SSC-380574 Dopamine synaptic vesicle docking and priming IEA Sus scrofa 59905 R-SSC-380869 https://reactome.org/PathwayBrowser/#/R-SSC-380869 Release of docked dopamine loaded synaptic vesicle IEA Sus scrofa 59905 R-SSC-390835 https://reactome.org/PathwayBrowser/#/R-SSC-390835 DRD1,5 bind DA IEA Sus scrofa 59905 R-SSC-390846 https://reactome.org/PathwayBrowser/#/R-SSC-390846 D2D3,4 bind to DA IEA Sus scrofa 59905 R-SSC-444160 https://reactome.org/PathwayBrowser/#/R-SSC-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Sus scrofa 59905 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 59905 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 59905 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 59905 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 59905 R-SSC-727740 https://reactome.org/PathwayBrowser/#/R-SSC-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 59905 R-SSC-727768 https://reactome.org/PathwayBrowser/#/R-SSC-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 59905 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 59905 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 59905 R-SSC-8955010 https://reactome.org/PathwayBrowser/#/R-SSC-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Sus scrofa 59905 R-SSC-9656244 https://reactome.org/PathwayBrowser/#/R-SSC-9656244 DRD2 binds DA IEA Sus scrofa 59905 R-XTR-159358 https://reactome.org/PathwayBrowser/#/R-XTR-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Xenopus tropicalis 59905 R-XTR-209891 https://reactome.org/PathwayBrowser/#/R-XTR-209891 Dopamine is oxidised to noradrenaline IEA Xenopus tropicalis 59905 R-XTR-209924 https://reactome.org/PathwayBrowser/#/R-XTR-209924 Dopa is decarboxylated to dopamine IEA Xenopus tropicalis 59905 R-XTR-372542 https://reactome.org/PathwayBrowser/#/R-XTR-372542 Loading of dopamine into synaptic veiscles IEA Xenopus tropicalis 59905 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 59905 R-XTR-379387 https://reactome.org/PathwayBrowser/#/R-XTR-379387 COMT transfers Met to DA to form 3MT IEA Xenopus tropicalis 59905 R-XTR-379393 https://reactome.org/PathwayBrowser/#/R-XTR-379393 SLC6A3 cotransports DA, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 59905 R-XTR-390835 https://reactome.org/PathwayBrowser/#/R-XTR-390835 DRD1,5 bind DA IEA Xenopus tropicalis 59905 R-XTR-444160 https://reactome.org/PathwayBrowser/#/R-XTR-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Xenopus tropicalis 59905 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 59905 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 59905 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 59905 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 60039 R-BTA-352052 https://reactome.org/PathwayBrowser/#/R-BTA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Bos taurus 60039 R-BTA-352059 https://reactome.org/PathwayBrowser/#/R-BTA-352059 SLC6A15-mediated amino acid uptake IEA Bos taurus 60039 R-BTA-352108 https://reactome.org/PathwayBrowser/#/R-BTA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Bos taurus 60039 R-BTA-375405 https://reactome.org/PathwayBrowser/#/R-BTA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Bos taurus 60039 R-BTA-375417 https://reactome.org/PathwayBrowser/#/R-BTA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Bos taurus 60039 R-BTA-444100 https://reactome.org/PathwayBrowser/#/R-BTA-444100 PROT mediates L-proline uptake IEA Bos taurus 60039 R-BTA-6783939 https://reactome.org/PathwayBrowser/#/R-BTA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 60039 R-BTA-6783955 https://reactome.org/PathwayBrowser/#/R-BTA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 60039 R-BTA-70664 https://reactome.org/PathwayBrowser/#/R-BTA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 60039 R-BTA-70670 https://reactome.org/PathwayBrowser/#/R-BTA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Bos taurus 60039 R-BTA-8870354 https://reactome.org/PathwayBrowser/#/R-BTA-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Bos taurus 60039 R-CEL-375405 https://reactome.org/PathwayBrowser/#/R-CEL-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Caenorhabditis elegans 60039 R-CEL-375417 https://reactome.org/PathwayBrowser/#/R-CEL-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Caenorhabditis elegans 60039 R-CEL-444100 https://reactome.org/PathwayBrowser/#/R-CEL-444100 PROT mediates L-proline uptake IEA Caenorhabditis elegans 60039 R-CEL-6783939 https://reactome.org/PathwayBrowser/#/R-CEL-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 60039 R-CEL-70664 https://reactome.org/PathwayBrowser/#/R-CEL-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 60039 R-CEL-70670 https://reactome.org/PathwayBrowser/#/R-CEL-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Caenorhabditis elegans 60039 R-CEL-8870354 https://reactome.org/PathwayBrowser/#/R-CEL-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Caenorhabditis elegans 60039 R-CFA-352052 https://reactome.org/PathwayBrowser/#/R-CFA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Canis familiaris 60039 R-CFA-352059 https://reactome.org/PathwayBrowser/#/R-CFA-352059 SLC6A15-mediated amino acid uptake IEA Canis familiaris 60039 R-CFA-352108 https://reactome.org/PathwayBrowser/#/R-CFA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Canis familiaris 60039 R-CFA-375405 https://reactome.org/PathwayBrowser/#/R-CFA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Canis familiaris 60039 R-CFA-375417 https://reactome.org/PathwayBrowser/#/R-CFA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Canis familiaris 60039 R-CFA-444100 https://reactome.org/PathwayBrowser/#/R-CFA-444100 PROT mediates L-proline uptake IEA Canis familiaris 60039 R-CFA-6783939 https://reactome.org/PathwayBrowser/#/R-CFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 60039 R-CFA-6783955 https://reactome.org/PathwayBrowser/#/R-CFA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 60039 R-CFA-70664 https://reactome.org/PathwayBrowser/#/R-CFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 60039 R-CFA-70670 https://reactome.org/PathwayBrowser/#/R-CFA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Canis familiaris 60039 R-CFA-8870354 https://reactome.org/PathwayBrowser/#/R-CFA-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Canis familiaris 60039 R-DDI-375405 https://reactome.org/PathwayBrowser/#/R-DDI-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Dictyostelium discoideum 60039 R-DDI-375417 https://reactome.org/PathwayBrowser/#/R-DDI-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Dictyostelium discoideum 60039 R-DDI-6783939 https://reactome.org/PathwayBrowser/#/R-DDI-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 60039 R-DDI-6783955 https://reactome.org/PathwayBrowser/#/R-DDI-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 60039 R-DDI-70664 https://reactome.org/PathwayBrowser/#/R-DDI-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 60039 R-DDI-70670 https://reactome.org/PathwayBrowser/#/R-DDI-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Dictyostelium discoideum 60039 R-DDI-8870354 https://reactome.org/PathwayBrowser/#/R-DDI-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Dictyostelium discoideum 60039 R-DME-352052 https://reactome.org/PathwayBrowser/#/R-DME-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Drosophila melanogaster 60039 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster 60039 R-DME-352108 https://reactome.org/PathwayBrowser/#/R-DME-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Drosophila melanogaster 60039 R-DME-375405 https://reactome.org/PathwayBrowser/#/R-DME-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Drosophila melanogaster 60039 R-DME-375417 https://reactome.org/PathwayBrowser/#/R-DME-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Drosophila melanogaster 60039 R-DME-444100 https://reactome.org/PathwayBrowser/#/R-DME-444100 PROT mediates L-proline uptake IEA Drosophila melanogaster 60039 R-DME-6783939 https://reactome.org/PathwayBrowser/#/R-DME-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 60039 R-DME-70664 https://reactome.org/PathwayBrowser/#/R-DME-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 60039 R-DME-70670 https://reactome.org/PathwayBrowser/#/R-DME-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Drosophila melanogaster 60039 R-DME-8870354 https://reactome.org/PathwayBrowser/#/R-DME-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Drosophila melanogaster 60039 R-DRE-352059 https://reactome.org/PathwayBrowser/#/R-DRE-352059 SLC6A15-mediated amino acid uptake IEA Danio rerio 60039 R-DRE-352108 https://reactome.org/PathwayBrowser/#/R-DRE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Danio rerio 60039 R-DRE-6783939 https://reactome.org/PathwayBrowser/#/R-DRE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 60039 R-DRE-6783955 https://reactome.org/PathwayBrowser/#/R-DRE-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 60039 R-DRE-70664 https://reactome.org/PathwayBrowser/#/R-DRE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 60039 R-DRE-8870354 https://reactome.org/PathwayBrowser/#/R-DRE-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Danio rerio 60039 R-GGA-352052 https://reactome.org/PathwayBrowser/#/R-GGA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Gallus gallus 60039 R-GGA-352059 https://reactome.org/PathwayBrowser/#/R-GGA-352059 SLC6A15-mediated amino acid uptake IEA Gallus gallus 60039 R-GGA-352108 https://reactome.org/PathwayBrowser/#/R-GGA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Gallus gallus 60039 R-GGA-375405 https://reactome.org/PathwayBrowser/#/R-GGA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Gallus gallus 60039 R-GGA-375417 https://reactome.org/PathwayBrowser/#/R-GGA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Gallus gallus 60039 R-GGA-444100 https://reactome.org/PathwayBrowser/#/R-GGA-444100 PROT mediates L-proline uptake IEA Gallus gallus 60039 R-GGA-6783939 https://reactome.org/PathwayBrowser/#/R-GGA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 60039 R-GGA-6783955 https://reactome.org/PathwayBrowser/#/R-GGA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 60039 R-GGA-70664 https://reactome.org/PathwayBrowser/#/R-GGA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 60039 R-GGA-70670 https://reactome.org/PathwayBrowser/#/R-GGA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Gallus gallus 60039 R-GGA-8870354 https://reactome.org/PathwayBrowser/#/R-GGA-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Gallus gallus 60039 R-HSA-352052 https://reactome.org/PathwayBrowser/#/R-HSA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol TAS Homo sapiens 60039 R-HSA-352059 https://reactome.org/PathwayBrowser/#/R-HSA-352059 SLC6A15-mediated amino acid uptake TAS Homo sapiens 60039 R-HSA-352108 https://reactome.org/PathwayBrowser/#/R-HSA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids TAS Homo sapiens 60039 R-HSA-375405 https://reactome.org/PathwayBrowser/#/R-HSA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol TAS Homo sapiens 60039 R-HSA-375417 https://reactome.org/PathwayBrowser/#/R-HSA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine TAS Homo sapiens 60039 R-HSA-379865 https://reactome.org/PathwayBrowser/#/R-HSA-379865 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate TAS Homo sapiens 60039 R-HSA-380198 https://reactome.org/PathwayBrowser/#/R-HSA-380198 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate IEA Homo sapiens 60039 R-HSA-444100 https://reactome.org/PathwayBrowser/#/R-HSA-444100 PROT mediates L-proline uptake TAS Homo sapiens 60039 R-HSA-5653850 https://reactome.org/PathwayBrowser/#/R-HSA-5653850 Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol TAS Homo sapiens 60039 R-HSA-5660694 https://reactome.org/PathwayBrowser/#/R-HSA-5660694 Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol TAS Homo sapiens 60039 R-HSA-6783939 https://reactome.org/PathwayBrowser/#/R-HSA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 60039 R-HSA-6783955 https://reactome.org/PathwayBrowser/#/R-HSA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 60039 R-HSA-70664 https://reactome.org/PathwayBrowser/#/R-HSA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 60039 R-HSA-70670 https://reactome.org/PathwayBrowser/#/R-HSA-70670 PRODH oxidises L-Pro to 1PYR-5COOH TAS Homo sapiens 60039 R-HSA-8870354 https://reactome.org/PathwayBrowser/#/R-HSA-8870354 SLC36A4 transports extracellular L-Pro to the cytosol TAS Homo sapiens 60039 R-MMU-352052 https://reactome.org/PathwayBrowser/#/R-MMU-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Mus musculus 60039 R-MMU-352059 https://reactome.org/PathwayBrowser/#/R-MMU-352059 SLC6A15-mediated amino acid uptake IEA Mus musculus 60039 R-MMU-352108 https://reactome.org/PathwayBrowser/#/R-MMU-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Mus musculus 60039 R-MMU-375405 https://reactome.org/PathwayBrowser/#/R-MMU-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Mus musculus 60039 R-MMU-375417 https://reactome.org/PathwayBrowser/#/R-MMU-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Mus musculus 60039 R-MMU-444100 https://reactome.org/PathwayBrowser/#/R-MMU-444100 PROT mediates L-proline uptake IEA Mus musculus 60039 R-MMU-6783939 https://reactome.org/PathwayBrowser/#/R-MMU-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 60039 R-MMU-6783955 https://reactome.org/PathwayBrowser/#/R-MMU-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 60039 R-MMU-70664 https://reactome.org/PathwayBrowser/#/R-MMU-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 60039 R-MMU-70670 https://reactome.org/PathwayBrowser/#/R-MMU-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Mus musculus 60039 R-MMU-8870354 https://reactome.org/PathwayBrowser/#/R-MMU-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Mus musculus 60039 R-PFA-352052 https://reactome.org/PathwayBrowser/#/R-PFA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Plasmodium falciparum 60039 R-PFA-352059 https://reactome.org/PathwayBrowser/#/R-PFA-352059 SLC6A15-mediated amino acid uptake IEA Plasmodium falciparum 60039 R-PFA-444100 https://reactome.org/PathwayBrowser/#/R-PFA-444100 PROT mediates L-proline uptake IEA Plasmodium falciparum 60039 R-PFA-6783939 https://reactome.org/PathwayBrowser/#/R-PFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 60039 R-PFA-6783955 https://reactome.org/PathwayBrowser/#/R-PFA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 60039 R-PFA-70664 https://reactome.org/PathwayBrowser/#/R-PFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 60039 R-RNO-352052 https://reactome.org/PathwayBrowser/#/R-RNO-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Rattus norvegicus 60039 R-RNO-352059 https://reactome.org/PathwayBrowser/#/R-RNO-352059 SLC6A15-mediated amino acid uptake IEA Rattus norvegicus 60039 R-RNO-352108 https://reactome.org/PathwayBrowser/#/R-RNO-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Rattus norvegicus 60039 R-RNO-375405 https://reactome.org/PathwayBrowser/#/R-RNO-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Rattus norvegicus 60039 R-RNO-375417 https://reactome.org/PathwayBrowser/#/R-RNO-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Rattus norvegicus 60039 R-RNO-444100 https://reactome.org/PathwayBrowser/#/R-RNO-444100 PROT mediates L-proline uptake IEA Rattus norvegicus 60039 R-RNO-6783939 https://reactome.org/PathwayBrowser/#/R-RNO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 60039 R-RNO-6783955 https://reactome.org/PathwayBrowser/#/R-RNO-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 60039 R-RNO-70664 https://reactome.org/PathwayBrowser/#/R-RNO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 60039 R-RNO-70670 https://reactome.org/PathwayBrowser/#/R-RNO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Rattus norvegicus 60039 R-RNO-8870354 https://reactome.org/PathwayBrowser/#/R-RNO-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Rattus norvegicus 60039 R-SCE-352108 https://reactome.org/PathwayBrowser/#/R-SCE-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Saccharomyces cerevisiae 60039 R-SCE-375405 https://reactome.org/PathwayBrowser/#/R-SCE-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 60039 R-SCE-375417 https://reactome.org/PathwayBrowser/#/R-SCE-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Saccharomyces cerevisiae 60039 R-SCE-6783939 https://reactome.org/PathwayBrowser/#/R-SCE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 60039 R-SCE-6783955 https://reactome.org/PathwayBrowser/#/R-SCE-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 60039 R-SCE-70664 https://reactome.org/PathwayBrowser/#/R-SCE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 60039 R-SCE-70670 https://reactome.org/PathwayBrowser/#/R-SCE-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Saccharomyces cerevisiae 60039 R-SCE-8870354 https://reactome.org/PathwayBrowser/#/R-SCE-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Saccharomyces cerevisiae 60039 R-SPO-6783939 https://reactome.org/PathwayBrowser/#/R-SPO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 60039 R-SPO-6783955 https://reactome.org/PathwayBrowser/#/R-SPO-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 60039 R-SPO-70664 https://reactome.org/PathwayBrowser/#/R-SPO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 60039 R-SPO-70670 https://reactome.org/PathwayBrowser/#/R-SPO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Schizosaccharomyces pombe 60039 R-SSC-352052 https://reactome.org/PathwayBrowser/#/R-SSC-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Sus scrofa 60039 R-SSC-352059 https://reactome.org/PathwayBrowser/#/R-SSC-352059 SLC6A15-mediated amino acid uptake IEA Sus scrofa 60039 R-SSC-352108 https://reactome.org/PathwayBrowser/#/R-SSC-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Sus scrofa 60039 R-SSC-375405 https://reactome.org/PathwayBrowser/#/R-SSC-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Sus scrofa 60039 R-SSC-375417 https://reactome.org/PathwayBrowser/#/R-SSC-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Sus scrofa 60039 R-SSC-444100 https://reactome.org/PathwayBrowser/#/R-SSC-444100 PROT mediates L-proline uptake IEA Sus scrofa 60039 R-SSC-6783939 https://reactome.org/PathwayBrowser/#/R-SSC-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 60039 R-SSC-6783955 https://reactome.org/PathwayBrowser/#/R-SSC-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 60039 R-SSC-70664 https://reactome.org/PathwayBrowser/#/R-SSC-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 60039 R-SSC-70670 https://reactome.org/PathwayBrowser/#/R-SSC-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Sus scrofa 60039 R-SSC-8870354 https://reactome.org/PathwayBrowser/#/R-SSC-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Sus scrofa 60039 R-XTR-352052 https://reactome.org/PathwayBrowser/#/R-XTR-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Xenopus tropicalis 60039 R-XTR-352059 https://reactome.org/PathwayBrowser/#/R-XTR-352059 SLC6A15-mediated amino acid uptake IEA Xenopus tropicalis 60039 R-XTR-352108 https://reactome.org/PathwayBrowser/#/R-XTR-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids IEA Xenopus tropicalis 60039 R-XTR-375405 https://reactome.org/PathwayBrowser/#/R-XTR-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Xenopus tropicalis 60039 R-XTR-375417 https://reactome.org/PathwayBrowser/#/R-XTR-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Xenopus tropicalis 60039 R-XTR-444100 https://reactome.org/PathwayBrowser/#/R-XTR-444100 PROT mediates L-proline uptake IEA Xenopus tropicalis 60039 R-XTR-6783939 https://reactome.org/PathwayBrowser/#/R-XTR-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 60039 R-XTR-70664 https://reactome.org/PathwayBrowser/#/R-XTR-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 60039 R-XTR-70670 https://reactome.org/PathwayBrowser/#/R-XTR-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Xenopus tropicalis 60039 R-XTR-8870354 https://reactome.org/PathwayBrowser/#/R-XTR-8870354 SLC36A4 transports extracellular L-Pro to the cytosol IEA Xenopus tropicalis 60065 R-BTA-1605595 https://reactome.org/PathwayBrowser/#/R-BTA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Bos taurus 60065 R-BTA-1605723 https://reactome.org/PathwayBrowser/#/R-BTA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Bos taurus 60065 R-BTA-1605724 https://reactome.org/PathwayBrowser/#/R-BTA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Bos taurus 60065 R-BTA-1605768 https://reactome.org/PathwayBrowser/#/R-BTA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Bos taurus 60065 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 60065 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 60065 R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 60065 R-CEL-1605595 https://reactome.org/PathwayBrowser/#/R-CEL-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Caenorhabditis elegans 60065 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 60065 R-CFA-1605595 https://reactome.org/PathwayBrowser/#/R-CFA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Canis familiaris 60065 R-CFA-1605723 https://reactome.org/PathwayBrowser/#/R-CFA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Canis familiaris 60065 R-CFA-1605724 https://reactome.org/PathwayBrowser/#/R-CFA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Canis familiaris 60065 R-CFA-1605768 https://reactome.org/PathwayBrowser/#/R-CFA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Canis familiaris 60065 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 60065 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 60065 R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 60065 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 60065 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 60065 R-DRE-1605723 https://reactome.org/PathwayBrowser/#/R-DRE-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Danio rerio 60065 R-DRE-1605768 https://reactome.org/PathwayBrowser/#/R-DRE-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Danio rerio 60065 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 60065 R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 60065 R-GGA-1605723 https://reactome.org/PathwayBrowser/#/R-GGA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Gallus gallus 60065 R-GGA-1605724 https://reactome.org/PathwayBrowser/#/R-GGA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Gallus gallus 60065 R-GGA-1605768 https://reactome.org/PathwayBrowser/#/R-GGA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Gallus gallus 60065 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 60065 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 60065 R-HSA-1605595 https://reactome.org/PathwayBrowser/#/R-HSA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 TAS Homo sapiens 60065 R-HSA-1605723 https://reactome.org/PathwayBrowser/#/R-HSA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) TAS Homo sapiens 60065 R-HSA-1605724 https://reactome.org/PathwayBrowser/#/R-HSA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE TAS Homo sapiens 60065 R-HSA-1605768 https://reactome.org/PathwayBrowser/#/R-HSA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) TAS Homo sapiens 60065 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 60065 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 60065 R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 60065 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 60065 R-MMU-1605595 https://reactome.org/PathwayBrowser/#/R-MMU-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Mus musculus 60065 R-MMU-1605723 https://reactome.org/PathwayBrowser/#/R-MMU-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Mus musculus 60065 R-MMU-1605724 https://reactome.org/PathwayBrowser/#/R-MMU-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Mus musculus 60065 R-MMU-1605768 https://reactome.org/PathwayBrowser/#/R-MMU-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Mus musculus 60065 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 60065 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 60065 R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 60065 R-RNO-1605595 https://reactome.org/PathwayBrowser/#/R-RNO-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Rattus norvegicus 60065 R-RNO-1605723 https://reactome.org/PathwayBrowser/#/R-RNO-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Rattus norvegicus 60065 R-RNO-1605724 https://reactome.org/PathwayBrowser/#/R-RNO-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Rattus norvegicus 60065 R-RNO-1605768 https://reactome.org/PathwayBrowser/#/R-RNO-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Rattus norvegicus 60065 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 60065 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 60065 R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 60065 R-SSC-1605595 https://reactome.org/PathwayBrowser/#/R-SSC-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Sus scrofa 60065 R-SSC-1605723 https://reactome.org/PathwayBrowser/#/R-SSC-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Sus scrofa 60065 R-SSC-1605724 https://reactome.org/PathwayBrowser/#/R-SSC-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Sus scrofa 60065 R-SSC-1605768 https://reactome.org/PathwayBrowser/#/R-SSC-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Sus scrofa 60065 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 60065 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 60065 R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 60065 R-XTR-1605723 https://reactome.org/PathwayBrowser/#/R-XTR-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Xenopus tropicalis 60065 R-XTR-1605768 https://reactome.org/PathwayBrowser/#/R-XTR-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Xenopus tropicalis 60065 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 60102 R-BTA-947499 https://reactome.org/PathwayBrowser/#/R-BTA-947499 Exchange of oxygen with sulfur in MoCo IEA Bos taurus 60102 R-CEL-947499 https://reactome.org/PathwayBrowser/#/R-CEL-947499 Exchange of oxygen with sulfur in MoCo IEA Caenorhabditis elegans 60102 R-CFA-947499 https://reactome.org/PathwayBrowser/#/R-CFA-947499 Exchange of oxygen with sulfur in MoCo IEA Canis familiaris 60102 R-DDI-947499 https://reactome.org/PathwayBrowser/#/R-DDI-947499 Exchange of oxygen with sulfur in MoCo IEA Dictyostelium discoideum 60102 R-DME-947499 https://reactome.org/PathwayBrowser/#/R-DME-947499 Exchange of oxygen with sulfur in MoCo IEA Drosophila melanogaster 60102 R-DRE-947499 https://reactome.org/PathwayBrowser/#/R-DRE-947499 Exchange of oxygen with sulfur in MoCo IEA Danio rerio 60102 R-GGA-947499 https://reactome.org/PathwayBrowser/#/R-GGA-947499 Exchange of oxygen with sulfur in MoCo IEA Gallus gallus 60102 R-HSA-947499 https://reactome.org/PathwayBrowser/#/R-HSA-947499 Exchange of oxygen with sulfur in MoCo TAS Homo sapiens 60102 R-MMU-947499 https://reactome.org/PathwayBrowser/#/R-MMU-947499 Exchange of oxygen with sulfur in MoCo IEA Mus musculus 60102 R-RNO-947499 https://reactome.org/PathwayBrowser/#/R-RNO-947499 Exchange of oxygen with sulfur in MoCo IEA Rattus norvegicus 60102 R-SSC-947499 https://reactome.org/PathwayBrowser/#/R-SSC-947499 Exchange of oxygen with sulfur in MoCo IEA Sus scrofa 60110 R-HSA-1482939 https://reactome.org/PathwayBrowser/#/R-HSA-1482939 CDP-DAG is converted to PGP by PGS1 IEA Homo sapiens 60110 R-HSA-1483197 https://reactome.org/PathwayBrowser/#/R-HSA-1483197 PTPMT1 dephosphorylates PGP to PG IEA Homo sapiens 60110 R-MMU-3446785 https://reactome.org/PathwayBrowser/#/R-MMU-3446785 Ptpmt1 dephosphorylates PGP to PG TAS Mus musculus 60110 R-RNO-1482978 https://reactome.org/PathwayBrowser/#/R-RNO-1482978 CDP-DAG is converted to PGP by Pgs1 TAS Rattus norvegicus 60119 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 60119 R-BTA-419428 https://reactome.org/PathwayBrowser/#/R-BTA-419428 S1PR2-5 bind S1P IEA Bos taurus 60119 R-BTA-428681 https://reactome.org/PathwayBrowser/#/R-BTA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Bos taurus 60119 R-BTA-428690 https://reactome.org/PathwayBrowser/#/R-BTA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Bos taurus 60119 R-BTA-428696 https://reactome.org/PathwayBrowser/#/R-BTA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Bos taurus 60119 R-BTA-5218845 https://reactome.org/PathwayBrowser/#/R-BTA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Bos taurus 60119 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 60119 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 60119 R-BTA-9624272 https://reactome.org/PathwayBrowser/#/R-BTA-9624272 MMPs cleave HB-EGF IEA Bos taurus 60119 R-BTA-9625813 https://reactome.org/PathwayBrowser/#/R-BTA-9625813 S1P binds S1PR3 in response to E2 stimulation IEA Bos taurus 60119 R-BTA-9625814 https://reactome.org/PathwayBrowser/#/R-BTA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Bos taurus 60119 R-BTA-9690449 https://reactome.org/PathwayBrowser/#/R-BTA-9690449 S1PR1 bind S1P IEA Bos taurus 60119 R-BTA-9843721 https://reactome.org/PathwayBrowser/#/R-BTA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Bos taurus 60119 R-CEL-428681 https://reactome.org/PathwayBrowser/#/R-CEL-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Caenorhabditis elegans 60119 R-CEL-428690 https://reactome.org/PathwayBrowser/#/R-CEL-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Caenorhabditis elegans 60119 R-CEL-428696 https://reactome.org/PathwayBrowser/#/R-CEL-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Caenorhabditis elegans 60119 R-CEL-9625814 https://reactome.org/PathwayBrowser/#/R-CEL-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Caenorhabditis elegans 60119 R-CEL-9843721 https://reactome.org/PathwayBrowser/#/R-CEL-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Caenorhabditis elegans 60119 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 60119 R-CFA-419428 https://reactome.org/PathwayBrowser/#/R-CFA-419428 S1PR2-5 bind S1P IEA Canis familiaris 60119 R-CFA-428681 https://reactome.org/PathwayBrowser/#/R-CFA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Canis familiaris 60119 R-CFA-428690 https://reactome.org/PathwayBrowser/#/R-CFA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Canis familiaris 60119 R-CFA-428696 https://reactome.org/PathwayBrowser/#/R-CFA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Canis familiaris 60119 R-CFA-5218845 https://reactome.org/PathwayBrowser/#/R-CFA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Canis familiaris 60119 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 60119 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 60119 R-CFA-9624272 https://reactome.org/PathwayBrowser/#/R-CFA-9624272 MMPs cleave HB-EGF IEA Canis familiaris 60119 R-CFA-9625813 https://reactome.org/PathwayBrowser/#/R-CFA-9625813 S1P binds S1PR3 in response to E2 stimulation IEA Canis familiaris 60119 R-CFA-9625814 https://reactome.org/PathwayBrowser/#/R-CFA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Canis familiaris 60119 R-CFA-9690449 https://reactome.org/PathwayBrowser/#/R-CFA-9690449 S1PR1 bind S1P IEA Canis familiaris 60119 R-CFA-9843721 https://reactome.org/PathwayBrowser/#/R-CFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Canis familiaris 60119 R-DDI-428681 https://reactome.org/PathwayBrowser/#/R-DDI-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Dictyostelium discoideum 60119 R-DDI-428690 https://reactome.org/PathwayBrowser/#/R-DDI-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Dictyostelium discoideum 60119 R-DDI-428696 https://reactome.org/PathwayBrowser/#/R-DDI-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Dictyostelium discoideum 60119 R-DDI-9625814 https://reactome.org/PathwayBrowser/#/R-DDI-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Dictyostelium discoideum 60119 R-DDI-9843721 https://reactome.org/PathwayBrowser/#/R-DDI-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Dictyostelium discoideum 60119 R-DME-428681 https://reactome.org/PathwayBrowser/#/R-DME-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Drosophila melanogaster 60119 R-DME-428690 https://reactome.org/PathwayBrowser/#/R-DME-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Drosophila melanogaster 60119 R-DME-428696 https://reactome.org/PathwayBrowser/#/R-DME-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Drosophila melanogaster 60119 R-DME-5218845 https://reactome.org/PathwayBrowser/#/R-DME-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Drosophila melanogaster 60119 R-DME-9625814 https://reactome.org/PathwayBrowser/#/R-DME-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Drosophila melanogaster 60119 R-DME-9843721 https://reactome.org/PathwayBrowser/#/R-DME-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Drosophila melanogaster 60119 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 60119 R-DRE-419428 https://reactome.org/PathwayBrowser/#/R-DRE-419428 S1PR2-5 bind S1P IEA Danio rerio 60119 R-DRE-428696 https://reactome.org/PathwayBrowser/#/R-DRE-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Danio rerio 60119 R-DRE-9690449 https://reactome.org/PathwayBrowser/#/R-DRE-9690449 S1PR1 bind S1P IEA Danio rerio 60119 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 60119 R-GGA-419428 https://reactome.org/PathwayBrowser/#/R-GGA-419428 S1PR2-5 bind S1P IEA Gallus gallus 60119 R-GGA-428681 https://reactome.org/PathwayBrowser/#/R-GGA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Gallus gallus 60119 R-GGA-428690 https://reactome.org/PathwayBrowser/#/R-GGA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Gallus gallus 60119 R-GGA-428696 https://reactome.org/PathwayBrowser/#/R-GGA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Gallus gallus 60119 R-GGA-5218845 https://reactome.org/PathwayBrowser/#/R-GGA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Gallus gallus 60119 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 60119 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 60119 R-GGA-9624272 https://reactome.org/PathwayBrowser/#/R-GGA-9624272 MMPs cleave HB-EGF IEA Gallus gallus 60119 R-GGA-9625813 https://reactome.org/PathwayBrowser/#/R-GGA-9625813 S1P binds S1PR3 in response to E2 stimulation IEA Gallus gallus 60119 R-GGA-9625814 https://reactome.org/PathwayBrowser/#/R-GGA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Gallus gallus 60119 R-GGA-9690449 https://reactome.org/PathwayBrowser/#/R-GGA-9690449 S1PR1 bind S1P IEA Gallus gallus 60119 R-GGA-9843721 https://reactome.org/PathwayBrowser/#/R-GGA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Gallus gallus 60119 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 60119 R-HSA-419428 https://reactome.org/PathwayBrowser/#/R-HSA-419428 S1PR2-5 bind S1P TAS Homo sapiens 60119 R-HSA-428681 https://reactome.org/PathwayBrowser/#/R-HSA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates TAS Homo sapiens 60119 R-HSA-428690 https://reactome.org/PathwayBrowser/#/R-HSA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate TAS Homo sapiens 60119 R-HSA-428696 https://reactome.org/PathwayBrowser/#/R-HSA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate TAS Homo sapiens 60119 R-HSA-5218845 https://reactome.org/PathwayBrowser/#/R-HSA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate TAS Homo sapiens 60119 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 60119 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 60119 R-HSA-9624272 https://reactome.org/PathwayBrowser/#/R-HSA-9624272 MMPs cleave HB-EGF TAS Homo sapiens 60119 R-HSA-9625813 https://reactome.org/PathwayBrowser/#/R-HSA-9625813 S1P binds S1PR3 in response to E2 stimulation TAS Homo sapiens 60119 R-HSA-9625814 https://reactome.org/PathwayBrowser/#/R-HSA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation TAS Homo sapiens 60119 R-HSA-9690449 https://reactome.org/PathwayBrowser/#/R-HSA-9690449 S1PR1 bind S1P TAS Homo sapiens 60119 R-HSA-9843721 https://reactome.org/PathwayBrowser/#/R-HSA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region TAS Homo sapiens 60119 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 60119 R-MMU-419428 https://reactome.org/PathwayBrowser/#/R-MMU-419428 S1PR2-5 bind S1P IEA Mus musculus 60119 R-MMU-428681 https://reactome.org/PathwayBrowser/#/R-MMU-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Mus musculus 60119 R-MMU-428690 https://reactome.org/PathwayBrowser/#/R-MMU-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Mus musculus 60119 R-MMU-428696 https://reactome.org/PathwayBrowser/#/R-MMU-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Mus musculus 60119 R-MMU-5218845 https://reactome.org/PathwayBrowser/#/R-MMU-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Mus musculus 60119 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 60119 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 60119 R-MMU-9624272 https://reactome.org/PathwayBrowser/#/R-MMU-9624272 MMPs cleave HB-EGF IEA Mus musculus 60119 R-MMU-9625813 https://reactome.org/PathwayBrowser/#/R-MMU-9625813 S1P binds S1PR3 in response to E2 stimulation IEA Mus musculus 60119 R-MMU-9625814 https://reactome.org/PathwayBrowser/#/R-MMU-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Mus musculus 60119 R-MMU-9690449 https://reactome.org/PathwayBrowser/#/R-MMU-9690449 S1PR1 bind S1P IEA Mus musculus 60119 R-MMU-9843721 https://reactome.org/PathwayBrowser/#/R-MMU-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Mus musculus 60119 R-PFA-9843721 https://reactome.org/PathwayBrowser/#/R-PFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Plasmodium falciparum 60119 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 60119 R-RNO-419428 https://reactome.org/PathwayBrowser/#/R-RNO-419428 S1PR2-5 bind S1P IEA Rattus norvegicus 60119 R-RNO-428681 https://reactome.org/PathwayBrowser/#/R-RNO-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Rattus norvegicus 60119 R-RNO-428690 https://reactome.org/PathwayBrowser/#/R-RNO-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Rattus norvegicus 60119 R-RNO-428696 https://reactome.org/PathwayBrowser/#/R-RNO-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Rattus norvegicus 60119 R-RNO-5218845 https://reactome.org/PathwayBrowser/#/R-RNO-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Rattus norvegicus 60119 R-RNO-9624272 https://reactome.org/PathwayBrowser/#/R-RNO-9624272 MMPs cleave HB-EGF IEA Rattus norvegicus 60119 R-RNO-9625813 https://reactome.org/PathwayBrowser/#/R-RNO-9625813 S1P binds S1PR3 in response to E2 stimulation IEA Rattus norvegicus 60119 R-RNO-9625814 https://reactome.org/PathwayBrowser/#/R-RNO-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Rattus norvegicus 60119 R-RNO-9690449 https://reactome.org/PathwayBrowser/#/R-RNO-9690449 S1PR1 bind S1P IEA Rattus norvegicus 60119 R-RNO-9843721 https://reactome.org/PathwayBrowser/#/R-RNO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Rattus norvegicus 60119 R-SCE-428681 https://reactome.org/PathwayBrowser/#/R-SCE-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Saccharomyces cerevisiae 60119 R-SCE-428690 https://reactome.org/PathwayBrowser/#/R-SCE-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Saccharomyces cerevisiae 60119 R-SCE-428696 https://reactome.org/PathwayBrowser/#/R-SCE-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Saccharomyces cerevisiae 60119 R-SCE-9625814 https://reactome.org/PathwayBrowser/#/R-SCE-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Saccharomyces cerevisiae 60119 R-SCE-9843721 https://reactome.org/PathwayBrowser/#/R-SCE-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Saccharomyces cerevisiae 60119 R-SPO-428690 https://reactome.org/PathwayBrowser/#/R-SPO-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Schizosaccharomyces pombe 60119 R-SPO-428696 https://reactome.org/PathwayBrowser/#/R-SPO-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Schizosaccharomyces pombe 60119 R-SPO-9625814 https://reactome.org/PathwayBrowser/#/R-SPO-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Schizosaccharomyces pombe 60119 R-SPO-9843721 https://reactome.org/PathwayBrowser/#/R-SPO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Schizosaccharomyces pombe 60119 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 60119 R-SSC-419428 https://reactome.org/PathwayBrowser/#/R-SSC-419428 S1PR2-5 bind S1P IEA Sus scrofa 60119 R-SSC-428681 https://reactome.org/PathwayBrowser/#/R-SSC-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Sus scrofa 60119 R-SSC-428690 https://reactome.org/PathwayBrowser/#/R-SSC-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Sus scrofa 60119 R-SSC-428696 https://reactome.org/PathwayBrowser/#/R-SSC-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Sus scrofa 60119 R-SSC-5218845 https://reactome.org/PathwayBrowser/#/R-SSC-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Sus scrofa 60119 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 60119 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 60119 R-SSC-9624272 https://reactome.org/PathwayBrowser/#/R-SSC-9624272 MMPs cleave HB-EGF IEA Sus scrofa 60119 R-SSC-9625813 https://reactome.org/PathwayBrowser/#/R-SSC-9625813 S1P binds S1PR3 in response to E2 stimulation IEA Sus scrofa 60119 R-SSC-9625814 https://reactome.org/PathwayBrowser/#/R-SSC-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Sus scrofa 60119 R-SSC-9690449 https://reactome.org/PathwayBrowser/#/R-SSC-9690449 S1PR1 bind S1P IEA Sus scrofa 60119 R-SSC-9843721 https://reactome.org/PathwayBrowser/#/R-SSC-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Sus scrofa 60119 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 60119 R-XTR-419428 https://reactome.org/PathwayBrowser/#/R-XTR-419428 S1PR2-5 bind S1P IEA Xenopus tropicalis 60119 R-XTR-428681 https://reactome.org/PathwayBrowser/#/R-XTR-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Xenopus tropicalis 60119 R-XTR-428696 https://reactome.org/PathwayBrowser/#/R-XTR-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Xenopus tropicalis 60119 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 60119 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 60119 R-XTR-9624272 https://reactome.org/PathwayBrowser/#/R-XTR-9624272 MMPs cleave HB-EGF IEA Xenopus tropicalis 60119 R-XTR-9625813 https://reactome.org/PathwayBrowser/#/R-XTR-9625813 S1P binds S1PR3 in response to E2 stimulation IEA Xenopus tropicalis 60119 R-XTR-9690449 https://reactome.org/PathwayBrowser/#/R-XTR-9690449 S1PR1 bind S1P IEA Xenopus tropicalis 60119 R-XTR-9843721 https://reactome.org/PathwayBrowser/#/R-XTR-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Xenopus tropicalis 60125 R-BTA-168166 https://reactome.org/PathwayBrowser/#/R-BTA-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Bos taurus 60125 R-BTA-2197770 https://reactome.org/PathwayBrowser/#/R-BTA-2197770 STAB1 (FEEL-1) binds ligands IEA Bos taurus 60125 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 60125 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 60125 R-BTA-2247513 https://reactome.org/PathwayBrowser/#/R-BTA-2247513 STAB1:ligand is endocytosed IEA Bos taurus 60125 R-BTA-879411 https://reactome.org/PathwayBrowser/#/R-BTA-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Bos taurus 60125 R-CFA-168166 https://reactome.org/PathwayBrowser/#/R-CFA-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Canis familiaris 60125 R-CFA-2197770 https://reactome.org/PathwayBrowser/#/R-CFA-2197770 STAB1 (FEEL-1) binds ligands IEA Canis familiaris 60125 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 60125 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 60125 R-CFA-2247513 https://reactome.org/PathwayBrowser/#/R-CFA-2247513 STAB1:ligand is endocytosed IEA Canis familiaris 60125 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 60125 R-CFA-879411 https://reactome.org/PathwayBrowser/#/R-CFA-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Canis familiaris 60125 R-DDI-879411 https://reactome.org/PathwayBrowser/#/R-DDI-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Dictyostelium discoideum 60125 R-DRE-2197770 https://reactome.org/PathwayBrowser/#/R-DRE-2197770 STAB1 (FEEL-1) binds ligands IEA Danio rerio 60125 R-DRE-2247513 https://reactome.org/PathwayBrowser/#/R-DRE-2247513 STAB1:ligand is endocytosed IEA Danio rerio 60125 R-GGA-2197770 https://reactome.org/PathwayBrowser/#/R-GGA-2197770 STAB1 (FEEL-1) binds ligands IEA Gallus gallus 60125 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 60125 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 60125 R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus 60125 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 60125 R-HSA-168166 https://reactome.org/PathwayBrowser/#/R-HSA-168166 NF-kappa-B complex is transported from cytosol to nucleus TAS Homo sapiens 60125 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 60125 R-HSA-2197770 https://reactome.org/PathwayBrowser/#/R-HSA-2197770 STAB1 (FEEL-1) binds ligands TAS Homo sapiens 60125 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 60125 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 60125 R-HSA-2247513 https://reactome.org/PathwayBrowser/#/R-HSA-2247513 STAB1:ligand is endocytosed TAS Homo sapiens 60125 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 60125 R-HSA-879358 https://reactome.org/PathwayBrowser/#/R-HSA-879358 AGER-1,2,3 bind AGEs IEA Homo sapiens 60125 R-HSA-879362 https://reactome.org/PathwayBrowser/#/R-HSA-879362 AGER binds ERK1/2 IEA Homo sapiens 60125 R-HSA-879411 https://reactome.org/PathwayBrowser/#/R-HSA-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor TAS Homo sapiens 60125 R-MMU-168166 https://reactome.org/PathwayBrowser/#/R-MMU-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Mus musculus 60125 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 60125 R-MMU-2197770 https://reactome.org/PathwayBrowser/#/R-MMU-2197770 STAB1 (FEEL-1) binds ligands IEA Mus musculus 60125 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 60125 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 60125 R-MMU-2247513 https://reactome.org/PathwayBrowser/#/R-MMU-2247513 STAB1:ligand is endocytosed IEA Mus musculus 60125 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 60125 R-MMU-879411 https://reactome.org/PathwayBrowser/#/R-MMU-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Mus musculus 60125 R-NUL-879372 https://reactome.org/PathwayBrowser/#/R-NUL-879372 Ager-1,2,3 bind AGEs TAS Rattus norvegicus 60125 R-NUL-997411 https://reactome.org/PathwayBrowser/#/R-NUL-997411 AGER binds rat ERK1/2 TAS Homo sapiens 60125 R-RNO-168166 https://reactome.org/PathwayBrowser/#/R-RNO-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Rattus norvegicus 60125 R-RNO-2197770 https://reactome.org/PathwayBrowser/#/R-RNO-2197770 STAB1 (FEEL-1) binds ligands IEA Rattus norvegicus 60125 R-RNO-2247513 https://reactome.org/PathwayBrowser/#/R-RNO-2247513 STAB1:ligand is endocytosed IEA Rattus norvegicus 60125 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 60125 R-RNO-879411 https://reactome.org/PathwayBrowser/#/R-RNO-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Rattus norvegicus 60125 R-SSC-168166 https://reactome.org/PathwayBrowser/#/R-SSC-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Sus scrofa 60125 R-SSC-2197770 https://reactome.org/PathwayBrowser/#/R-SSC-2197770 STAB1 (FEEL-1) binds ligands IEA Sus scrofa 60125 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 60125 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 60125 R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa 60125 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 60125 R-SSC-879411 https://reactome.org/PathwayBrowser/#/R-SSC-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Sus scrofa 60125 R-XTR-879411 https://reactome.org/PathwayBrowser/#/R-XTR-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Xenopus tropicalis 60156 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 60156 R-BTA-8869683 https://reactome.org/PathwayBrowser/#/R-BTA-8869683 oxPL binds LBP IEA Bos taurus 60156 R-BTA-8869694 https://reactome.org/PathwayBrowser/#/R-BTA-8869694 oxPL binds CD14 IEA Bos taurus 60156 R-BTA-9707586 https://reactome.org/PathwayBrowser/#/R-BTA-9707586 FeHM oxidises LDL,HDL IEA Bos taurus 60156 R-CEL-8869683 https://reactome.org/PathwayBrowser/#/R-CEL-8869683 oxPL binds LBP IEA Caenorhabditis elegans 60156 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 60156 R-CFA-8869683 https://reactome.org/PathwayBrowser/#/R-CFA-8869683 oxPL binds LBP IEA Canis familiaris 60156 R-CFA-8869694 https://reactome.org/PathwayBrowser/#/R-CFA-8869694 oxPL binds CD14 IEA Canis familiaris 60156 R-CFA-9707586 https://reactome.org/PathwayBrowser/#/R-CFA-9707586 FeHM oxidises LDL,HDL IEA Canis familiaris 60156 R-DDI-8869683 https://reactome.org/PathwayBrowser/#/R-DDI-8869683 oxPL binds LBP IEA Dictyostelium discoideum 60156 R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 60156 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 60156 R-GGA-8869683 https://reactome.org/PathwayBrowser/#/R-GGA-8869683 oxPL binds LBP IEA Gallus gallus 60156 R-GGA-8869694 https://reactome.org/PathwayBrowser/#/R-GGA-8869694 oxPL binds CD14 IEA Gallus gallus 60156 R-GGA-9707586 https://reactome.org/PathwayBrowser/#/R-GGA-9707586 FeHM oxidises LDL,HDL IEA Gallus gallus 60156 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 60156 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 60156 R-HSA-8869683 https://reactome.org/PathwayBrowser/#/R-HSA-8869683 oxPL binds LBP TAS Homo sapiens 60156 R-HSA-8869694 https://reactome.org/PathwayBrowser/#/R-HSA-8869694 oxPL binds CD14 TAS Homo sapiens 60156 R-HSA-9707586 https://reactome.org/PathwayBrowser/#/R-HSA-9707586 FeHM oxidises LDL,HDL TAS Homo sapiens 60156 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 60156 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 60156 R-MMU-8869683 https://reactome.org/PathwayBrowser/#/R-MMU-8869683 oxPL binds LBP IEA Mus musculus 60156 R-MMU-8869694 https://reactome.org/PathwayBrowser/#/R-MMU-8869694 oxPL binds CD14 IEA Mus musculus 60156 R-MMU-9707586 https://reactome.org/PathwayBrowser/#/R-MMU-9707586 FeHM oxidises LDL,HDL IEA Mus musculus 60156 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 60156 R-RNO-8869683 https://reactome.org/PathwayBrowser/#/R-RNO-8869683 oxPL binds LBP IEA Rattus norvegicus 60156 R-RNO-8869694 https://reactome.org/PathwayBrowser/#/R-RNO-8869694 oxPL binds CD14 IEA Rattus norvegicus 60156 R-RNO-9707586 https://reactome.org/PathwayBrowser/#/R-RNO-9707586 FeHM oxidises LDL,HDL IEA Rattus norvegicus 60156 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 60156 R-SSC-8869683 https://reactome.org/PathwayBrowser/#/R-SSC-8869683 oxPL binds LBP IEA Sus scrofa 60156 R-SSC-8869694 https://reactome.org/PathwayBrowser/#/R-SSC-8869694 oxPL binds CD14 IEA Sus scrofa 60156 R-SSC-9707586 https://reactome.org/PathwayBrowser/#/R-SSC-9707586 FeHM oxidises LDL,HDL IEA Sus scrofa 60156 R-XTR-8869683 https://reactome.org/PathwayBrowser/#/R-XTR-8869683 oxPL binds LBP IEA Xenopus tropicalis 60175 R-BTA-6788611 https://reactome.org/PathwayBrowser/#/R-BTA-6788611 HYKK phosphorylates 5HLYS IEA Bos taurus 60175 R-CFA-6788611 https://reactome.org/PathwayBrowser/#/R-CFA-6788611 HYKK phosphorylates 5HLYS IEA Canis familiaris 60175 R-DME-6788611 https://reactome.org/PathwayBrowser/#/R-DME-6788611 HYKK phosphorylates 5HLYS IEA Drosophila melanogaster 60175 R-DRE-6788611 https://reactome.org/PathwayBrowser/#/R-DRE-6788611 HYKK phosphorylates 5HLYS IEA Danio rerio 60175 R-GGA-6788611 https://reactome.org/PathwayBrowser/#/R-GGA-6788611 HYKK phosphorylates 5HLYS IEA Gallus gallus 60175 R-HSA-6788611 https://reactome.org/PathwayBrowser/#/R-HSA-6788611 HYKK phosphorylates 5HLYS TAS Homo sapiens 60175 R-MMU-6788611 https://reactome.org/PathwayBrowser/#/R-MMU-6788611 HYKK phosphorylates 5HLYS IEA Mus musculus 60175 R-RNO-6788611 https://reactome.org/PathwayBrowser/#/R-RNO-6788611 HYKK phosphorylates 5HLYS IEA Rattus norvegicus 60175 R-SSC-6788611 https://reactome.org/PathwayBrowser/#/R-SSC-6788611 HYKK phosphorylates 5HLYS IEA Sus scrofa 60175 R-XTR-6788611 https://reactome.org/PathwayBrowser/#/R-XTR-6788611 HYKK phosphorylates 5HLYS IEA Xenopus tropicalis 60192 R-GGA-433864 https://reactome.org/PathwayBrowser/#/R-GGA-433864 IRAK2 binds to the IRAK4 accociated with the complex of the activated TLR : TIRAP : MyD88 IEA Gallus gallus 60192 R-GGA-433961 https://reactome.org/PathwayBrowser/#/R-GGA-433961 Activated TLR homo- or heterodimer recruits adaptors TIRAP(or MAL) and MyD88 IEA Gallus gallus 60192 R-GGA-434018 https://reactome.org/PathwayBrowser/#/R-GGA-434018 Autophosphorylation of chicken IRAK4 IEA Gallus gallus 60192 R-GGA-434047 https://reactome.org/PathwayBrowser/#/R-GGA-434047 phosphorylation of IRAK2 by activated IRAK4 IEA Gallus gallus 60192 R-GGA-434053 https://reactome.org/PathwayBrowser/#/R-GGA-434053 TRAF6 binds to p-IRAK2 complexed with activated TLR IEA Gallus gallus 60192 R-GGA-434073 https://reactome.org/PathwayBrowser/#/R-GGA-434073 IRAK4 recruitment to the activated TLR complexed with ligand, TIRAP and MyD88 IEA Gallus gallus 60192 R-GGA-434084 https://reactome.org/PathwayBrowser/#/R-GGA-434084 p-IRAK2- TRAF6 dissociates from the activated chTLR complex IEA Gallus gallus 60192 R-GGA-517846 https://reactome.org/PathwayBrowser/#/R-GGA-517846 TLR2-1 :TLR1-1 binds to triacyl lipopeptide TAS Gallus gallus 60192 R-GGA-517850 https://reactome.org/PathwayBrowser/#/R-GGA-517850 TLR2-1 : TLR1-2 heterodimer binds to its ligand TAS Gallus gallus 60192 R-HSA-166072 https://reactome.org/PathwayBrowser/#/R-HSA-166072 MyD88 forms a complex with TIRAP:activated TLR2/4 TAS Homo sapiens 60192 R-HSA-166082 https://reactome.org/PathwayBrowser/#/R-HSA-166082 IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex TAS Homo sapiens 60192 R-HSA-166091 https://reactome.org/PathwayBrowser/#/R-HSA-166091 IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex TAS Homo sapiens 60192 R-HSA-166119 https://reactome.org/PathwayBrowser/#/R-HSA-166119 First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal TAS Homo sapiens 60192 R-HSA-166284 https://reactome.org/PathwayBrowser/#/R-HSA-166284 Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP TAS Homo sapiens 60192 R-HSA-166286 https://reactome.org/PathwayBrowser/#/R-HSA-166286 Multiple IRAK1 autophosphorylation steps TAS Homo sapiens 60192 R-HSA-166362 https://reactome.org/PathwayBrowser/#/R-HSA-166362 Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 60192 R-HSA-166363 https://reactome.org/PathwayBrowser/#/R-HSA-166363 TRAF6 binds to hp- IRAK1 TAS Homo sapiens 60192 R-HSA-168951 https://reactome.org/PathwayBrowser/#/R-HSA-168951 TLR1:TLR2 is recruited to ligand:CD14 TAS Homo sapiens 60192 R-HSA-2201316 https://reactome.org/PathwayBrowser/#/R-HSA-2201316 Activated TLR2/4 interacts with MAL (TIRAP) TAS Homo sapiens 60192 R-HSA-2201322 https://reactome.org/PathwayBrowser/#/R-HSA-2201322 TIRAP is phosphorylated by BTK TAS Homo sapiens 60192 R-HSA-2262775 https://reactome.org/PathwayBrowser/#/R-HSA-2262775 Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 60192 R-HSA-2262777 https://reactome.org/PathwayBrowser/#/R-HSA-2262777 TRAF6 binds to p-IRAK2 TAS Homo sapiens 60192 R-HSA-2559414 https://reactome.org/PathwayBrowser/#/R-HSA-2559414 Activated TLR2/4:TIRAP interacts with BTK TAS Homo sapiens 60192 R-HSA-2559468 https://reactome.org/PathwayBrowser/#/R-HSA-2559468 TLR1/2 ligand binds to CD14 TAS Homo sapiens 60192 R-HSA-5602353 https://reactome.org/PathwayBrowser/#/R-HSA-5602353 Defective IRAK4 variants do not bind MyD88:MAL:BTK:activated TLR2/4 TAS Homo sapiens 60192 R-HSA-5602383 https://reactome.org/PathwayBrowser/#/R-HSA-5602383 Defective MyD88 does not oligomerize within the activated TLR2/4 complex TAS Homo sapiens 60192 R-HSA-5602606 https://reactome.org/PathwayBrowser/#/R-HSA-5602606 Defective MyD88 does not bind MAL(TIRAP):TLR2/4 TAS Homo sapiens 60192 R-HSA-5602672 https://reactome.org/PathwayBrowser/#/R-HSA-5602672 Defective IRAK4 does not bind MyD88 within the TLR2/4 complex TAS Homo sapiens 60192 R-HSA-8863895 https://reactome.org/PathwayBrowser/#/R-HSA-8863895 IKKB phosphorylates SNAP23 TAS Homo sapiens 60192 R-HSA-937022 https://reactome.org/PathwayBrowser/#/R-HSA-937022 IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP TAS Homo sapiens 60192 R-HSA-937059 https://reactome.org/PathwayBrowser/#/R-HSA-937059 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex TAS Homo sapiens 60192 R-HSA-937079 https://reactome.org/PathwayBrowser/#/R-HSA-937079 MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 TAS Homo sapiens 60240 R-BTA-5251989 https://reactome.org/PathwayBrowser/#/R-BTA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Bos taurus 60240 R-CEL-5251989 https://reactome.org/PathwayBrowser/#/R-CEL-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Caenorhabditis elegans 60240 R-CFA-5251989 https://reactome.org/PathwayBrowser/#/R-CFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Canis familiaris 60240 R-DDI-5251989 https://reactome.org/PathwayBrowser/#/R-DDI-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Dictyostelium discoideum 60240 R-DME-5251989 https://reactome.org/PathwayBrowser/#/R-DME-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Drosophila melanogaster 60240 R-GGA-5251989 https://reactome.org/PathwayBrowser/#/R-GGA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Gallus gallus 60240 R-HSA-5251989 https://reactome.org/PathwayBrowser/#/R-HSA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol TAS Homo sapiens 60240 R-MMU-5251989 https://reactome.org/PathwayBrowser/#/R-MMU-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Mus musculus 60240 R-PFA-5251989 https://reactome.org/PathwayBrowser/#/R-PFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Plasmodium falciparum 60240 R-RNO-5251989 https://reactome.org/PathwayBrowser/#/R-RNO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Rattus norvegicus 60240 R-SCE-5251989 https://reactome.org/PathwayBrowser/#/R-SCE-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Saccharomyces cerevisiae 60240 R-SPO-5251989 https://reactome.org/PathwayBrowser/#/R-SPO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Schizosaccharomyces pombe 60240 R-SSC-5251989 https://reactome.org/PathwayBrowser/#/R-SSC-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Sus scrofa 60240 R-XTR-5251989 https://reactome.org/PathwayBrowser/#/R-XTR-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Xenopus tropicalis 6030 R-BTA-174967 https://reactome.org/PathwayBrowser/#/R-BTA-174967 NAT2 acetylation IEA Bos taurus 6030 R-DRE-174967 https://reactome.org/PathwayBrowser/#/R-DRE-174967 NAT2 acetylation IEA Danio rerio 6030 R-GGA-174967 https://reactome.org/PathwayBrowser/#/R-GGA-174967 NAT2 acetylation IEA Gallus gallus 6030 R-HSA-174967 https://reactome.org/PathwayBrowser/#/R-HSA-174967 NAT2 acetylation TAS Homo sapiens 6030 R-MMU-174967 https://reactome.org/PathwayBrowser/#/R-MMU-174967 NAT2 acetylation IEA Mus musculus 6030 R-RNO-174967 https://reactome.org/PathwayBrowser/#/R-RNO-174967 NAT2 acetylation IEA Rattus norvegicus 6030 R-SSC-174967 https://reactome.org/PathwayBrowser/#/R-SSC-174967 NAT2 acetylation IEA Sus scrofa 60344 R-BTA-1222376 https://reactome.org/PathwayBrowser/#/R-BTA-1222376 NOX2 generates superoxide from oxygen IEA Bos taurus 60344 R-BTA-1237325 https://reactome.org/PathwayBrowser/#/R-BTA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Bos taurus 60344 R-BTA-1247668 https://reactome.org/PathwayBrowser/#/R-BTA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Bos taurus 60344 R-BTA-1497784 https://reactome.org/PathwayBrowser/#/R-BTA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Bos taurus 60344 R-BTA-1497796 https://reactome.org/PathwayBrowser/#/R-BTA-1497796 BH2 binding can lead to eNOS uncoupling IEA Bos taurus 60344 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 60344 R-BTA-1614524 https://reactome.org/PathwayBrowser/#/R-BTA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Bos taurus 60344 R-BTA-189398 https://reactome.org/PathwayBrowser/#/R-BTA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Bos taurus 60344 R-BTA-189442 https://reactome.org/PathwayBrowser/#/R-BTA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Bos taurus 60344 R-BTA-189465 https://reactome.org/PathwayBrowser/#/R-BTA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Bos taurus 60344 R-BTA-198563 https://reactome.org/PathwayBrowser/#/R-BTA-198563 IDO1 dioxygenates L-Trp to NFK IEA Bos taurus 60344 R-BTA-198824 https://reactome.org/PathwayBrowser/#/R-BTA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Bos taurus 60344 R-BTA-198845 https://reactome.org/PathwayBrowser/#/R-BTA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Bos taurus 60344 R-BTA-202110 https://reactome.org/PathwayBrowser/#/R-BTA-202110 eNOS:Caveolin-1 complex binds to CaM IEA Bos taurus 60344 R-BTA-202111 https://reactome.org/PathwayBrowser/#/R-BTA-202111 AKT1 phosphorylates eNOS IEA Bos taurus 60344 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 60344 R-BTA-202129 https://reactome.org/PathwayBrowser/#/R-BTA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Bos taurus 60344 R-BTA-202132 https://reactome.org/PathwayBrowser/#/R-BTA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Bos taurus 60344 R-BTA-202144 https://reactome.org/PathwayBrowser/#/R-BTA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Bos taurus 60344 R-BTA-203553 https://reactome.org/PathwayBrowser/#/R-BTA-203553 eNOS binds NOSIP IEA Bos taurus 60344 R-BTA-203565 https://reactome.org/PathwayBrowser/#/R-BTA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Bos taurus 60344 R-BTA-203613 https://reactome.org/PathwayBrowser/#/R-BTA-203613 depalmitoylation of eNOS IEA Bos taurus 60344 R-BTA-203625 https://reactome.org/PathwayBrowser/#/R-BTA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Bos taurus 60344 R-BTA-203680 https://reactome.org/PathwayBrowser/#/R-BTA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Bos taurus 60344 R-BTA-203700 https://reactome.org/PathwayBrowser/#/R-BTA-203700 eNOS translocation from Golgi to Caveolae IEA Bos taurus 60344 R-BTA-203712 https://reactome.org/PathwayBrowser/#/R-BTA-203712 eNOS associates with Caveolin-1 IEA Bos taurus 60344 R-BTA-2168886 https://reactome.org/PathwayBrowser/#/R-BTA-2168886 Hemopexin binds Hemes IEA Bos taurus 60344 R-BTA-2168897 https://reactome.org/PathwayBrowser/#/R-BTA-2168897 LRP1 (CD91) binds Hemopexin:heme IEA Bos taurus 60344 R-BTA-2230938 https://reactome.org/PathwayBrowser/#/R-BTA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Bos taurus 60344 R-BTA-2230983 https://reactome.org/PathwayBrowser/#/R-BTA-2230983 LRP1:Hemopexin:heme is endocytosed IEA Bos taurus 60344 R-BTA-2995330 https://reactome.org/PathwayBrowser/#/R-BTA-2995330 COX10 transforms heme to heme O IEA Bos taurus 60344 R-BTA-382560 https://reactome.org/PathwayBrowser/#/R-BTA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Bos taurus 60344 R-BTA-5218827 https://reactome.org/PathwayBrowser/#/R-BTA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Bos taurus 60344 R-BTA-5218841 https://reactome.org/PathwayBrowser/#/R-BTA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Bos taurus 60344 R-BTA-5340214 https://reactome.org/PathwayBrowser/#/R-BTA-5340214 CYGB binds O2 IEA Bos taurus 60344 R-BTA-5340226 https://reactome.org/PathwayBrowser/#/R-BTA-5340226 CYGB dioxygenates NO IEA Bos taurus 60344 R-BTA-6806831 https://reactome.org/PathwayBrowser/#/R-BTA-6806831 CYB5Rs reduce MetHb to HbA IEA Bos taurus 60344 R-BTA-71188 https://reactome.org/PathwayBrowser/#/R-BTA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Bos taurus 60344 R-BTA-76031 https://reactome.org/PathwayBrowser/#/R-BTA-76031 2 H2O2 => O2 + 2 H2O IEA Bos taurus 60344 R-BTA-888614 https://reactome.org/PathwayBrowser/#/R-BTA-888614 IDO2 dioxygenates L-Trp to NFK IEA Bos taurus 60344 R-BTA-8981606 https://reactome.org/PathwayBrowser/#/R-BTA-8981606 Myoglobin binds oxygen IEA Bos taurus 60344 R-BTA-8981610 https://reactome.org/PathwayBrowser/#/R-BTA-8981610 Neuroglobin binds oxygen IEA Bos taurus 60344 R-BTA-8981621 https://reactome.org/PathwayBrowser/#/R-BTA-8981621 Neuroglobin:oxygen dissociates IEA Bos taurus 60344 R-BTA-8981622 https://reactome.org/PathwayBrowser/#/R-BTA-8981622 Myoglobin:oxygen dissociates IEA Bos taurus 60344 R-BTA-8982617 https://reactome.org/PathwayBrowser/#/R-BTA-8982617 CYGB:O2 dissociates IEA Bos taurus 60344 R-BTA-9013145 https://reactome.org/PathwayBrowser/#/R-BTA-9013145 RAC1 binds effectors at the plasma membrane IEA Bos taurus 60344 R-BTA-9018808 https://reactome.org/PathwayBrowser/#/R-BTA-9018808 RAC3 binds effectors at the plasma membrane IEA Bos taurus 60344 R-BTA-917805 https://reactome.org/PathwayBrowser/#/R-BTA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Bos taurus 60344 R-BTA-917870 https://reactome.org/PathwayBrowser/#/R-BTA-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Bos taurus 60344 R-BTA-917892 https://reactome.org/PathwayBrowser/#/R-BTA-917892 FLVCR1-1 transports heme from cytosol to extracellular region IEA Bos taurus 60344 R-BTA-917979 https://reactome.org/PathwayBrowser/#/R-BTA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Bos taurus 60344 R-BTA-9661408 https://reactome.org/PathwayBrowser/#/R-BTA-9661408 FLVCR1-2 transports heme from mitochondrial matrix to cytosol IEA Bos taurus 60344 R-BTA-9661419 https://reactome.org/PathwayBrowser/#/R-BTA-9661419 ALB binds extracellular heme IEA Bos taurus 60344 R-BTA-9707504 https://reactome.org/PathwayBrowser/#/R-BTA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Bos taurus 60344 R-BTA-9707505 https://reactome.org/PathwayBrowser/#/R-BTA-9707505 Hemes bind to CLEC1B dimer IEA Bos taurus 60344 R-BTA-9707523 https://reactome.org/PathwayBrowser/#/R-BTA-9707523 Hemes bind to BACH1:MAFK IEA Bos taurus 60344 R-BTA-9707586 https://reactome.org/PathwayBrowser/#/R-BTA-9707586 FeHM oxidises LDL,HDL IEA Bos taurus 60344 R-BTA-9707594 https://reactome.org/PathwayBrowser/#/R-BTA-9707594 Hemes bind LY96 IEA Bos taurus 60344 R-BTA-9707606 https://reactome.org/PathwayBrowser/#/R-BTA-9707606 PGRMC2:Hemes translocate to the nucleus IEA Bos taurus 60344 R-BTA-9707659 https://reactome.org/PathwayBrowser/#/R-BTA-9707659 Hemes:LY96 activates TLR4 IEA Bos taurus 60344 R-BTA-9707683 https://reactome.org/PathwayBrowser/#/R-BTA-9707683 PGRMC2 binds Hemes IEA Bos taurus 60344 R-BTA-9707856 https://reactome.org/PathwayBrowser/#/R-BTA-9707856 PGRMC2:Hemes dissociates IEA Bos taurus 60344 R-BTA-9708423 https://reactome.org/PathwayBrowser/#/R-BTA-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Bos taurus 60344 R-BTA-9708430 https://reactome.org/PathwayBrowser/#/R-BTA-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Bos taurus 60344 R-BTA-9709317 https://reactome.org/PathwayBrowser/#/R-BTA-9709317 CO binds to free ferrohemoglobin IEA Bos taurus 60344 R-BTA-9709360 https://reactome.org/PathwayBrowser/#/R-BTA-9709360 H2O2 reduces MetHb IEA Bos taurus 60344 R-BTA-9838035 https://reactome.org/PathwayBrowser/#/R-BTA-9838035 CLPXP binds mitochondrial matrix proteins IEA Bos taurus 60344 R-BTA-9838289 https://reactome.org/PathwayBrowser/#/R-BTA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Bos taurus 60344 R-CEL-1497784 https://reactome.org/PathwayBrowser/#/R-CEL-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Caenorhabditis elegans 60344 R-CEL-1497796 https://reactome.org/PathwayBrowser/#/R-CEL-1497796 BH2 binding can lead to eNOS uncoupling IEA Caenorhabditis elegans 60344 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 60344 R-CEL-1614524 https://reactome.org/PathwayBrowser/#/R-CEL-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Caenorhabditis elegans 60344 R-CEL-189465 https://reactome.org/PathwayBrowser/#/R-CEL-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Caenorhabditis elegans 60344 R-CEL-198845 https://reactome.org/PathwayBrowser/#/R-CEL-198845 CYB5A:heme reduces Asc.- to AscH- IEA Caenorhabditis elegans 60344 R-CEL-202111 https://reactome.org/PathwayBrowser/#/R-CEL-202111 AKT1 phosphorylates eNOS IEA Caenorhabditis elegans 60344 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 60344 R-CEL-2168886 https://reactome.org/PathwayBrowser/#/R-CEL-2168886 Hemopexin binds Hemes IEA Caenorhabditis elegans 60344 R-CEL-2995330 https://reactome.org/PathwayBrowser/#/R-CEL-2995330 COX10 transforms heme to heme O IEA Caenorhabditis elegans 60344 R-CEL-382560 https://reactome.org/PathwayBrowser/#/R-CEL-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Caenorhabditis elegans 60344 R-CEL-5340214 https://reactome.org/PathwayBrowser/#/R-CEL-5340214 CYGB binds O2 IEA Caenorhabditis elegans 60344 R-CEL-5340226 https://reactome.org/PathwayBrowser/#/R-CEL-5340226 CYGB dioxygenates NO IEA Caenorhabditis elegans 60344 R-CEL-71188 https://reactome.org/PathwayBrowser/#/R-CEL-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Caenorhabditis elegans 60344 R-CEL-76031 https://reactome.org/PathwayBrowser/#/R-CEL-76031 2 H2O2 => O2 + 2 H2O IEA Caenorhabditis elegans 60344 R-CEL-8981610 https://reactome.org/PathwayBrowser/#/R-CEL-8981610 Neuroglobin binds oxygen IEA Caenorhabditis elegans 60344 R-CEL-8981621 https://reactome.org/PathwayBrowser/#/R-CEL-8981621 Neuroglobin:oxygen dissociates IEA Caenorhabditis elegans 60344 R-CEL-8982617 https://reactome.org/PathwayBrowser/#/R-CEL-8982617 CYGB:O2 dissociates IEA Caenorhabditis elegans 60344 R-CEL-917805 https://reactome.org/PathwayBrowser/#/R-CEL-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Caenorhabditis elegans 60344 R-CEL-917870 https://reactome.org/PathwayBrowser/#/R-CEL-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Caenorhabditis elegans 60344 R-CEL-917892 https://reactome.org/PathwayBrowser/#/R-CEL-917892 FLVCR1-1 transports heme from cytosol to extracellular region IEA Caenorhabditis elegans 60344 R-CEL-917979 https://reactome.org/PathwayBrowser/#/R-CEL-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Caenorhabditis elegans 60344 R-CEL-9661408 https://reactome.org/PathwayBrowser/#/R-CEL-9661408 FLVCR1-2 transports heme from mitochondrial matrix to cytosol IEA Caenorhabditis elegans 60344 R-CEL-9707505 https://reactome.org/PathwayBrowser/#/R-CEL-9707505 Hemes bind to CLEC1B dimer IEA Caenorhabditis elegans 60344 R-CEL-9707606 https://reactome.org/PathwayBrowser/#/R-CEL-9707606 PGRMC2:Hemes translocate to the nucleus IEA Caenorhabditis elegans 60344 R-CEL-9707683 https://reactome.org/PathwayBrowser/#/R-CEL-9707683 PGRMC2 binds Hemes IEA Caenorhabditis elegans 60344 R-CEL-9707856 https://reactome.org/PathwayBrowser/#/R-CEL-9707856 PGRMC2:Hemes dissociates IEA Caenorhabditis elegans 60344 R-CFA-1222376 https://reactome.org/PathwayBrowser/#/R-CFA-1222376 NOX2 generates superoxide from oxygen IEA Canis familiaris 60344 R-CFA-1237325 https://reactome.org/PathwayBrowser/#/R-CFA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Canis familiaris 60344 R-CFA-1247668 https://reactome.org/PathwayBrowser/#/R-CFA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Canis familiaris 60344 R-CFA-1614524 https://reactome.org/PathwayBrowser/#/R-CFA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Canis familiaris 60344 R-CFA-189398 https://reactome.org/PathwayBrowser/#/R-CFA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Canis familiaris 60344 R-CFA-189442 https://reactome.org/PathwayBrowser/#/R-CFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Canis familiaris 60344 R-CFA-189465 https://reactome.org/PathwayBrowser/#/R-CFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Canis familiaris 60344 R-CFA-198563 https://reactome.org/PathwayBrowser/#/R-CFA-198563 IDO1 dioxygenates L-Trp to NFK IEA Canis familiaris 60344 R-CFA-198824 https://reactome.org/PathwayBrowser/#/R-CFA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Canis familiaris 60344 R-CFA-198845 https://reactome.org/PathwayBrowser/#/R-CFA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Canis familiaris 60344 R-CFA-203565 https://reactome.org/PathwayBrowser/#/R-CFA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Canis familiaris 60344 R-CFA-203625 https://reactome.org/PathwayBrowser/#/R-CFA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Canis familiaris 60344 R-CFA-2230938 https://reactome.org/PathwayBrowser/#/R-CFA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Canis familiaris 60344 R-CFA-2995330 https://reactome.org/PathwayBrowser/#/R-CFA-2995330 COX10 transforms heme to heme O IEA Canis familiaris 60344 R-CFA-382560 https://reactome.org/PathwayBrowser/#/R-CFA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Canis familiaris 60344 R-CFA-5218827 https://reactome.org/PathwayBrowser/#/R-CFA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Canis familiaris 60344 R-CFA-5218841 https://reactome.org/PathwayBrowser/#/R-CFA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Canis familiaris 60344 R-CFA-5340214 https://reactome.org/PathwayBrowser/#/R-CFA-5340214 CYGB binds O2 IEA Canis familiaris 60344 R-CFA-5340226 https://reactome.org/PathwayBrowser/#/R-CFA-5340226 CYGB dioxygenates NO IEA Canis familiaris 60344 R-CFA-6806831 https://reactome.org/PathwayBrowser/#/R-CFA-6806831 CYB5Rs reduce MetHb to HbA IEA Canis familiaris 60344 R-CFA-71188 https://reactome.org/PathwayBrowser/#/R-CFA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Canis familiaris 60344 R-CFA-76031 https://reactome.org/PathwayBrowser/#/R-CFA-76031 2 H2O2 => O2 + 2 H2O IEA Canis familiaris 60344 R-CFA-888614 https://reactome.org/PathwayBrowser/#/R-CFA-888614 IDO2 dioxygenates L-Trp to NFK IEA Canis familiaris 60344 R-CFA-8981606 https://reactome.org/PathwayBrowser/#/R-CFA-8981606 Myoglobin binds oxygen IEA Canis familiaris 60344 R-CFA-8981610 https://reactome.org/PathwayBrowser/#/R-CFA-8981610 Neuroglobin binds oxygen IEA Canis familiaris 60344 R-CFA-8981621 https://reactome.org/PathwayBrowser/#/R-CFA-8981621 Neuroglobin:oxygen dissociates IEA Canis familiaris 60344 R-CFA-8981622 https://reactome.org/PathwayBrowser/#/R-CFA-8981622 Myoglobin:oxygen dissociates IEA Canis familiaris 60344 R-CFA-8982617 https://reactome.org/PathwayBrowser/#/R-CFA-8982617 CYGB:O2 dissociates IEA Canis familiaris 60344 R-CFA-9013145 https://reactome.org/PathwayBrowser/#/R-CFA-9013145 RAC1 binds effectors at the plasma membrane IEA Canis familiaris 60344 R-CFA-9018808 https://reactome.org/PathwayBrowser/#/R-CFA-9018808 RAC3 binds effectors at the plasma membrane IEA Canis familiaris 60344 R-CFA-917805 https://reactome.org/PathwayBrowser/#/R-CFA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Canis familiaris 60344 R-CFA-917870 https://reactome.org/PathwayBrowser/#/R-CFA-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Canis familiaris 60344 R-CFA-917892 https://reactome.org/PathwayBrowser/#/R-CFA-917892 FLVCR1-1 transports heme from cytosol to extracellular region IEA Canis familiaris 60344 R-CFA-917979 https://reactome.org/PathwayBrowser/#/R-CFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Canis familiaris 60344 R-CFA-9661408 https://reactome.org/PathwayBrowser/#/R-CFA-9661408 FLVCR1-2 transports heme from mitochondrial matrix to cytosol IEA Canis familiaris 60344 R-CFA-9661419 https://reactome.org/PathwayBrowser/#/R-CFA-9661419 ALB binds extracellular heme IEA Canis familiaris 60344 R-CFA-9707504 https://reactome.org/PathwayBrowser/#/R-CFA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Canis familiaris 60344 R-CFA-9707505 https://reactome.org/PathwayBrowser/#/R-CFA-9707505 Hemes bind to CLEC1B dimer IEA Canis familiaris 60344 R-CFA-9707523 https://reactome.org/PathwayBrowser/#/R-CFA-9707523 Hemes bind to BACH1:MAFK IEA Canis familiaris 60344 R-CFA-9707586 https://reactome.org/PathwayBrowser/#/R-CFA-9707586 FeHM oxidises LDL,HDL IEA Canis familiaris 60344 R-CFA-9707594 https://reactome.org/PathwayBrowser/#/R-CFA-9707594 Hemes bind LY96 IEA Canis familiaris 60344 R-CFA-9707606 https://reactome.org/PathwayBrowser/#/R-CFA-9707606 PGRMC2:Hemes translocate to the nucleus IEA Canis familiaris 60344 R-CFA-9707659 https://reactome.org/PathwayBrowser/#/R-CFA-9707659 Hemes:LY96 activates TLR4 IEA Canis familiaris 60344 R-CFA-9707683 https://reactome.org/PathwayBrowser/#/R-CFA-9707683 PGRMC2 binds Hemes IEA Canis familiaris 60344 R-CFA-9707856 https://reactome.org/PathwayBrowser/#/R-CFA-9707856 PGRMC2:Hemes dissociates IEA Canis familiaris 60344 R-CFA-9708423 https://reactome.org/PathwayBrowser/#/R-CFA-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Canis familiaris 60344 R-CFA-9708430 https://reactome.org/PathwayBrowser/#/R-CFA-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Canis familiaris 60344 R-CFA-9709317 https://reactome.org/PathwayBrowser/#/R-CFA-9709317 CO binds to free ferrohemoglobin IEA Canis familiaris 60344 R-CFA-9709360 https://reactome.org/PathwayBrowser/#/R-CFA-9709360 H2O2 reduces MetHb IEA Canis familiaris 60344 R-CFA-9838035 https://reactome.org/PathwayBrowser/#/R-CFA-9838035 CLPXP binds mitochondrial matrix proteins IEA Canis familiaris 60344 R-CFA-9838289 https://reactome.org/PathwayBrowser/#/R-CFA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Canis familiaris 60344 R-DDI-1497784 https://reactome.org/PathwayBrowser/#/R-DDI-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Dictyostelium discoideum 60344 R-DDI-1497796 https://reactome.org/PathwayBrowser/#/R-DDI-1497796 BH2 binding can lead to eNOS uncoupling IEA Dictyostelium discoideum 60344 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 60344 R-DDI-1614524 https://reactome.org/PathwayBrowser/#/R-DDI-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Dictyostelium discoideum 60344 R-DDI-189442 https://reactome.org/PathwayBrowser/#/R-DDI-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Dictyostelium discoideum 60344 R-DDI-189465 https://reactome.org/PathwayBrowser/#/R-DDI-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Dictyostelium discoideum 60344 R-DDI-198824 https://reactome.org/PathwayBrowser/#/R-DDI-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Dictyostelium discoideum 60344 R-DDI-198845 https://reactome.org/PathwayBrowser/#/R-DDI-198845 CYB5A:heme reduces Asc.- to AscH- IEA Dictyostelium discoideum 60344 R-DDI-202111 https://reactome.org/PathwayBrowser/#/R-DDI-202111 AKT1 phosphorylates eNOS IEA Dictyostelium discoideum 60344 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 60344 R-DDI-202132 https://reactome.org/PathwayBrowser/#/R-DDI-202132 depalmitoylated eNOS translocates from plasma membrane IEA Dictyostelium discoideum 60344 R-DDI-202137 https://reactome.org/PathwayBrowser/#/R-DDI-202137 AKT1 binds eNOS complex via HSP90 IEA Dictyostelium discoideum 60344 R-DDI-203553 https://reactome.org/PathwayBrowser/#/R-DDI-203553 eNOS binds NOSIP IEA Dictyostelium discoideum 60344 R-DDI-203613 https://reactome.org/PathwayBrowser/#/R-DDI-203613 depalmitoylation of eNOS IEA Dictyostelium discoideum 60344 R-DDI-203680 https://reactome.org/PathwayBrowser/#/R-DDI-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Dictyostelium discoideum 60344 R-DDI-203700 https://reactome.org/PathwayBrowser/#/R-DDI-203700 eNOS translocation from Golgi to Caveolae IEA Dictyostelium discoideum 60344 R-DDI-2995330 https://reactome.org/PathwayBrowser/#/R-DDI-2995330 COX10 transforms heme to heme O IEA Dictyostelium discoideum 60344 R-DDI-382560 https://reactome.org/PathwayBrowser/#/R-DDI-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Dictyostelium discoideum 60344 R-DDI-71188 https://reactome.org/PathwayBrowser/#/R-DDI-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Dictyostelium discoideum 60344 R-DDI-76031 https://reactome.org/PathwayBrowser/#/R-DDI-76031 2 H2O2 => O2 + 2 H2O IEA Dictyostelium discoideum 60344 R-DDI-917979 https://reactome.org/PathwayBrowser/#/R-DDI-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Dictyostelium discoideum 60344 R-DDI-9707606 https://reactome.org/PathwayBrowser/#/R-DDI-9707606 PGRMC2:Hemes translocate to the nucleus IEA Dictyostelium discoideum 60344 R-DDI-9707683 https://reactome.org/PathwayBrowser/#/R-DDI-9707683 PGRMC2 binds Hemes IEA Dictyostelium discoideum 60344 R-DDI-9707856 https://reactome.org/PathwayBrowser/#/R-DDI-9707856 PGRMC2:Hemes dissociates IEA Dictyostelium discoideum 60344 R-DME-1497784 https://reactome.org/PathwayBrowser/#/R-DME-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Drosophila melanogaster 60344 R-DME-1497796 https://reactome.org/PathwayBrowser/#/R-DME-1497796 BH2 binding can lead to eNOS uncoupling IEA Drosophila melanogaster 60344 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 60344 R-DME-1614524 https://reactome.org/PathwayBrowser/#/R-DME-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Drosophila melanogaster 60344 R-DME-189398 https://reactome.org/PathwayBrowser/#/R-DME-189398 HMOX1 dimer, HMOX2 cleave heme IEA Drosophila melanogaster 60344 R-DME-189442 https://reactome.org/PathwayBrowser/#/R-DME-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Drosophila melanogaster 60344 R-DME-189465 https://reactome.org/PathwayBrowser/#/R-DME-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Drosophila melanogaster 60344 R-DME-198824 https://reactome.org/PathwayBrowser/#/R-DME-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Drosophila melanogaster 60344 R-DME-198845 https://reactome.org/PathwayBrowser/#/R-DME-198845 CYB5A:heme reduces Asc.- to AscH- IEA Drosophila melanogaster 60344 R-DME-202111 https://reactome.org/PathwayBrowser/#/R-DME-202111 AKT1 phosphorylates eNOS IEA Drosophila melanogaster 60344 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 60344 R-DME-202132 https://reactome.org/PathwayBrowser/#/R-DME-202132 depalmitoylated eNOS translocates from plasma membrane IEA Drosophila melanogaster 60344 R-DME-202137 https://reactome.org/PathwayBrowser/#/R-DME-202137 AKT1 binds eNOS complex via HSP90 IEA Drosophila melanogaster 60344 R-DME-203553 https://reactome.org/PathwayBrowser/#/R-DME-203553 eNOS binds NOSIP IEA Drosophila melanogaster 60344 R-DME-203613 https://reactome.org/PathwayBrowser/#/R-DME-203613 depalmitoylation of eNOS IEA Drosophila melanogaster 60344 R-DME-203680 https://reactome.org/PathwayBrowser/#/R-DME-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Drosophila melanogaster 60344 R-DME-203700 https://reactome.org/PathwayBrowser/#/R-DME-203700 eNOS translocation from Golgi to Caveolae IEA Drosophila melanogaster 60344 R-DME-2168886 https://reactome.org/PathwayBrowser/#/R-DME-2168886 Hemopexin binds Hemes IEA Drosophila melanogaster 60344 R-DME-2995330 https://reactome.org/PathwayBrowser/#/R-DME-2995330 COX10 transforms heme to heme O IEA Drosophila melanogaster 60344 R-DME-382560 https://reactome.org/PathwayBrowser/#/R-DME-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Drosophila melanogaster 60344 R-DME-71188 https://reactome.org/PathwayBrowser/#/R-DME-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Drosophila melanogaster 60344 R-DME-76031 https://reactome.org/PathwayBrowser/#/R-DME-76031 2 H2O2 => O2 + 2 H2O IEA Drosophila melanogaster 60344 R-DME-917805 https://reactome.org/PathwayBrowser/#/R-DME-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Drosophila melanogaster 60344 R-DME-917870 https://reactome.org/PathwayBrowser/#/R-DME-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Drosophila melanogaster 60344 R-DME-917892 https://reactome.org/PathwayBrowser/#/R-DME-917892 FLVCR1-1 transports heme from cytosol to extracellular region IEA Drosophila melanogaster 60344 R-DME-917979 https://reactome.org/PathwayBrowser/#/R-DME-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Drosophila melanogaster 60344 R-DME-9661408 https://reactome.org/PathwayBrowser/#/R-DME-9661408 FLVCR1-2 transports heme from mitochondrial matrix to cytosol IEA Drosophila melanogaster 60344 R-DME-9707523 https://reactome.org/PathwayBrowser/#/R-DME-9707523 Hemes bind to BACH1:MAFK IEA Drosophila melanogaster 60344 R-DME-9707606 https://reactome.org/PathwayBrowser/#/R-DME-9707606 PGRMC2:Hemes translocate to the nucleus IEA Drosophila melanogaster 60344 R-DME-9707683 https://reactome.org/PathwayBrowser/#/R-DME-9707683 PGRMC2 binds Hemes IEA Drosophila melanogaster 60344 R-DME-9707856 https://reactome.org/PathwayBrowser/#/R-DME-9707856 PGRMC2:Hemes dissociates IEA Drosophila melanogaster 60344 R-DME-9708423 https://reactome.org/PathwayBrowser/#/R-DME-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Drosophila melanogaster 60344 R-DME-9708430 https://reactome.org/PathwayBrowser/#/R-DME-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Drosophila melanogaster 60344 R-DME-9838035 https://reactome.org/PathwayBrowser/#/R-DME-9838035 CLPXP binds mitochondrial matrix proteins IEA Drosophila melanogaster 60344 R-DME-9838289 https://reactome.org/PathwayBrowser/#/R-DME-9838289 CLPXP degrades mitochondrial matrix proteins IEA Drosophila melanogaster 60344 R-DRE-1222376 https://reactome.org/PathwayBrowser/#/R-DRE-1222376 NOX2 generates superoxide from oxygen IEA Danio rerio 60344 R-DRE-1237325 https://reactome.org/PathwayBrowser/#/R-DRE-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Danio rerio 60344 R-DRE-1247668 https://reactome.org/PathwayBrowser/#/R-DRE-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Danio rerio 60344 R-DRE-1614524 https://reactome.org/PathwayBrowser/#/R-DRE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Danio rerio 60344 R-DRE-189398 https://reactome.org/PathwayBrowser/#/R-DRE-189398 HMOX1 dimer, HMOX2 cleave heme IEA Danio rerio 60344 R-DRE-189442 https://reactome.org/PathwayBrowser/#/R-DRE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Danio rerio 60344 R-DRE-189465 https://reactome.org/PathwayBrowser/#/R-DRE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Danio rerio 60344 R-DRE-198824 https://reactome.org/PathwayBrowser/#/R-DRE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Danio rerio 60344 R-DRE-198845 https://reactome.org/PathwayBrowser/#/R-DRE-198845 CYB5A:heme reduces Asc.- to AscH- IEA Danio rerio 60344 R-DRE-203565 https://reactome.org/PathwayBrowser/#/R-DRE-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Danio rerio 60344 R-DRE-203625 https://reactome.org/PathwayBrowser/#/R-DRE-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Danio rerio 60344 R-DRE-2168885 https://reactome.org/PathwayBrowser/#/R-DRE-2168885 Haptoglobin binds Hemoglobin IEA Danio rerio 60344 R-DRE-2230938 https://reactome.org/PathwayBrowser/#/R-DRE-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Danio rerio 60344 R-DRE-382560 https://reactome.org/PathwayBrowser/#/R-DRE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Danio rerio 60344 R-DRE-5218827 https://reactome.org/PathwayBrowser/#/R-DRE-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Danio rerio 60344 R-DRE-5218841 https://reactome.org/PathwayBrowser/#/R-DRE-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Danio rerio 60344 R-DRE-5340214 https://reactome.org/PathwayBrowser/#/R-DRE-5340214 CYGB binds O2 IEA Danio rerio 60344 R-DRE-5340226 https://reactome.org/PathwayBrowser/#/R-DRE-5340226 CYGB dioxygenates NO IEA Danio rerio 60344 R-DRE-6806831 https://reactome.org/PathwayBrowser/#/R-DRE-6806831 CYB5Rs reduce MetHb to HbA IEA Danio rerio 60344 R-DRE-71188 https://reactome.org/PathwayBrowser/#/R-DRE-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Danio rerio 60344 R-DRE-76031 https://reactome.org/PathwayBrowser/#/R-DRE-76031 2 H2O2 => O2 + 2 H2O IEA Danio rerio 60344 R-DRE-888614 https://reactome.org/PathwayBrowser/#/R-DRE-888614 IDO2 dioxygenates L-Trp to NFK IEA Danio rerio 60344 R-DRE-8981606 https://reactome.org/PathwayBrowser/#/R-DRE-8981606 Myoglobin binds oxygen IEA Danio rerio 60344 R-DRE-8981610 https://reactome.org/PathwayBrowser/#/R-DRE-8981610 Neuroglobin binds oxygen IEA Danio rerio 60344 R-DRE-8981621 https://reactome.org/PathwayBrowser/#/R-DRE-8981621 Neuroglobin:oxygen dissociates IEA Danio rerio 60344 R-DRE-8981622 https://reactome.org/PathwayBrowser/#/R-DRE-8981622 Myoglobin:oxygen dissociates IEA Danio rerio 60344 R-DRE-8982617 https://reactome.org/PathwayBrowser/#/R-DRE-8982617 CYGB:O2 dissociates IEA Danio rerio 60344 R-DRE-917805 https://reactome.org/PathwayBrowser/#/R-DRE-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Danio rerio 60344 R-DRE-917870 https://reactome.org/PathwayBrowser/#/R-DRE-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Danio rerio 60344 R-DRE-9707504 https://reactome.org/PathwayBrowser/#/R-DRE-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Danio rerio 60344 R-DRE-9707606 https://reactome.org/PathwayBrowser/#/R-DRE-9707606 PGRMC2:Hemes translocate to the nucleus IEA Danio rerio 60344 R-DRE-9707683 https://reactome.org/PathwayBrowser/#/R-DRE-9707683 PGRMC2 binds Hemes IEA Danio rerio 60344 R-DRE-9707856 https://reactome.org/PathwayBrowser/#/R-DRE-9707856 PGRMC2:Hemes dissociates IEA Danio rerio 60344 R-DRE-9709317 https://reactome.org/PathwayBrowser/#/R-DRE-9709317 CO binds to free ferrohemoglobin IEA Danio rerio 60344 R-DRE-9709360 https://reactome.org/PathwayBrowser/#/R-DRE-9709360 H2O2 reduces MetHb IEA Danio rerio 60344 R-GGA-1222376 https://reactome.org/PathwayBrowser/#/R-GGA-1222376 NOX2 generates superoxide from oxygen IEA Gallus gallus 60344 R-GGA-1237325 https://reactome.org/PathwayBrowser/#/R-GGA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Gallus gallus 60344 R-GGA-1247668 https://reactome.org/PathwayBrowser/#/R-GGA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Gallus gallus 60344 R-GGA-1497784 https://reactome.org/PathwayBrowser/#/R-GGA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Gallus gallus 60344 R-GGA-1497796 https://reactome.org/PathwayBrowser/#/R-GGA-1497796 BH2 binding can lead to eNOS uncoupling IEA Gallus gallus 60344 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 60344 R-GGA-1614524 https://reactome.org/PathwayBrowser/#/R-GGA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Gallus gallus 60344 R-GGA-189398 https://reactome.org/PathwayBrowser/#/R-GGA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Gallus gallus 60344 R-GGA-189442 https://reactome.org/PathwayBrowser/#/R-GGA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Gallus gallus 60344 R-GGA-189465 https://reactome.org/PathwayBrowser/#/R-GGA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Gallus gallus 60344 R-GGA-198824 https://reactome.org/PathwayBrowser/#/R-GGA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Gallus gallus 60344 R-GGA-198845 https://reactome.org/PathwayBrowser/#/R-GGA-198845 CYB5A:heme reduces Asc.- to AscH- IEA Gallus gallus 60344 R-GGA-202110 https://reactome.org/PathwayBrowser/#/R-GGA-202110 eNOS:Caveolin-1 complex binds to CaM IEA Gallus gallus 60344 R-GGA-202111 https://reactome.org/PathwayBrowser/#/R-GGA-202111 AKT1 phosphorylates eNOS IEA Gallus gallus 60344 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 60344 R-GGA-202129 https://reactome.org/PathwayBrowser/#/R-GGA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Gallus gallus 60344 R-GGA-202132 https://reactome.org/PathwayBrowser/#/R-GGA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Gallus gallus 60344 R-GGA-202137 https://reactome.org/PathwayBrowser/#/R-GGA-202137 AKT1 binds eNOS complex via HSP90 IEA Gallus gallus 60344 R-GGA-202144 https://reactome.org/PathwayBrowser/#/R-GGA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Gallus gallus 60344 R-GGA-203565 https://reactome.org/PathwayBrowser/#/R-GGA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Gallus gallus 60344 R-GGA-203613 https://reactome.org/PathwayBrowser/#/R-GGA-203613 depalmitoylation of eNOS IEA Gallus gallus 60344 R-GGA-203625 https://reactome.org/PathwayBrowser/#/R-GGA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Gallus gallus 60344 R-GGA-203700 https://reactome.org/PathwayBrowser/#/R-GGA-203700 eNOS translocation from Golgi to Caveolae IEA Gallus gallus 60344 R-GGA-203712 https://reactome.org/PathwayBrowser/#/R-GGA-203712 eNOS associates with Caveolin-1 IEA Gallus gallus 60344 R-GGA-2168885 https://reactome.org/PathwayBrowser/#/R-GGA-2168885 Haptoglobin binds Hemoglobin IEA Gallus gallus 60344 R-GGA-2230938 https://reactome.org/PathwayBrowser/#/R-GGA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Gallus gallus 60344 R-GGA-2995330 https://reactome.org/PathwayBrowser/#/R-GGA-2995330 COX10 transforms heme to heme O IEA Gallus gallus 60344 R-GGA-382560 https://reactome.org/PathwayBrowser/#/R-GGA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Gallus gallus 60344 R-GGA-421447 https://reactome.org/PathwayBrowser/#/R-GGA-421447 protoporphyrin IX + Fe++ => heme + 2 H+ TAS Gallus gallus 60344 R-GGA-5218827 https://reactome.org/PathwayBrowser/#/R-GGA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Gallus gallus 60344 R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus 60344 R-GGA-5340214 https://reactome.org/PathwayBrowser/#/R-GGA-5340214 CYGB binds O2 IEA Gallus gallus 60344 R-GGA-5340226 https://reactome.org/PathwayBrowser/#/R-GGA-5340226 CYGB dioxygenates NO IEA Gallus gallus 60344 R-GGA-6806831 https://reactome.org/PathwayBrowser/#/R-GGA-6806831 CYB5Rs reduce MetHb to HbA IEA Gallus gallus 60344 R-GGA-71188 https://reactome.org/PathwayBrowser/#/R-GGA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Gallus gallus 60344 R-GGA-76031 https://reactome.org/PathwayBrowser/#/R-GGA-76031 2 H2O2 => O2 + 2 H2O IEA Gallus gallus 60344 R-GGA-888614 https://reactome.org/PathwayBrowser/#/R-GGA-888614 IDO2 dioxygenates L-Trp to NFK IEA Gallus gallus 60344 R-GGA-8981606 https://reactome.org/PathwayBrowser/#/R-GGA-8981606 Myoglobin binds oxygen IEA Gallus gallus 60344 R-GGA-8981610 https://reactome.org/PathwayBrowser/#/R-GGA-8981610 Neuroglobin binds oxygen IEA Gallus gallus 60344 R-GGA-8981621 https://reactome.org/PathwayBrowser/#/R-GGA-8981621 Neuroglobin:oxygen dissociates IEA Gallus gallus 60344 R-GGA-8981622 https://reactome.org/PathwayBrowser/#/R-GGA-8981622 Myoglobin:oxygen dissociates IEA Gallus gallus 60344 R-GGA-8982617 https://reactome.org/PathwayBrowser/#/R-GGA-8982617 CYGB:O2 dissociates IEA Gallus gallus 60344 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus 60344 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus 60344 R-GGA-917805 https://reactome.org/PathwayBrowser/#/R-GGA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Gallus gallus 60344 R-GGA-917870 https://reactome.org/PathwayBrowser/#/R-GGA-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Gallus gallus 60344 R-GGA-917892 https://reactome.org/PathwayBrowser/#/R-GGA-917892 FLVCR1-1 transports heme from cytosol to extracellular region IEA Gallus gallus 60344 R-GGA-9661408 https://reactome.org/PathwayBrowser/#/R-GGA-9661408 FLVCR1-2 transports heme from mitochondrial matrix to cytosol IEA Gallus gallus 60344 R-GGA-9661419 https://reactome.org/PathwayBrowser/#/R-GGA-9661419 ALB binds extracellular heme IEA Gallus gallus 60344 R-GGA-9707504 https://reactome.org/PathwayBrowser/#/R-GGA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Gallus gallus 60344 R-GGA-9707523 https://reactome.org/PathwayBrowser/#/R-GGA-9707523 Hemes bind to BACH1:MAFK IEA Gallus gallus 60344 R-GGA-9707586 https://reactome.org/PathwayBrowser/#/R-GGA-9707586 FeHM oxidises LDL,HDL IEA Gallus gallus 60344 R-GGA-9707594 https://reactome.org/PathwayBrowser/#/R-GGA-9707594 Hemes bind LY96 IEA Gallus gallus 60344 R-GGA-9707606 https://reactome.org/PathwayBrowser/#/R-GGA-9707606 PGRMC2:Hemes translocate to the nucleus IEA Gallus gallus 60344 R-GGA-9707659 https://reactome.org/PathwayBrowser/#/R-GGA-9707659 Hemes:LY96 activates TLR4 IEA Gallus gallus 60344 R-GGA-9707683 https://reactome.org/PathwayBrowser/#/R-GGA-9707683 PGRMC2 binds Hemes IEA Gallus gallus 60344 R-GGA-9707856 https://reactome.org/PathwayBrowser/#/R-GGA-9707856 PGRMC2:Hemes dissociates IEA Gallus gallus 60344 R-GGA-9708423 https://reactome.org/PathwayBrowser/#/R-GGA-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Gallus gallus 60344 R-GGA-9708430 https://reactome.org/PathwayBrowser/#/R-GGA-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Gallus gallus 60344 R-GGA-9709317 https://reactome.org/PathwayBrowser/#/R-GGA-9709317 CO binds to free ferrohemoglobin IEA Gallus gallus 60344 R-GGA-9709360 https://reactome.org/PathwayBrowser/#/R-GGA-9709360 H2O2 reduces MetHb IEA Gallus gallus 60344 R-HSA-1222376 https://reactome.org/PathwayBrowser/#/R-HSA-1222376 NOX2 generates superoxide from oxygen TAS Homo sapiens 60344 R-HSA-1222512 https://reactome.org/PathwayBrowser/#/R-HSA-1222512 Nitric oxide oxidizes to nitrosyl ion TAS Homo sapiens 60344 R-HSA-1222704 https://reactome.org/PathwayBrowser/#/R-HSA-1222704 KatG reduces H2O2 TAS Homo sapiens 60344 R-HSA-1222723 https://reactome.org/PathwayBrowser/#/R-HSA-1222723 Nitric oxide is oxidized to nitrate TAS Homo sapiens 60344 R-HSA-1237325 https://reactome.org/PathwayBrowser/#/R-HSA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen TAS Homo sapiens 60344 R-HSA-1247668 https://reactome.org/PathwayBrowser/#/R-HSA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 TAS Homo sapiens 60344 R-HSA-1497784 https://reactome.org/PathwayBrowser/#/R-HSA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle TAS Homo sapiens 60344 R-HSA-1497796 https://reactome.org/PathwayBrowser/#/R-HSA-1497796 BH2 binding can lead to eNOS uncoupling TAS Homo sapiens 60344 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 60344 R-HSA-1562604 https://reactome.org/PathwayBrowser/#/R-HSA-1562604 BfrA stores iron TAS Homo sapiens 60344 R-HSA-1614524 https://reactome.org/PathwayBrowser/#/R-HSA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine TAS Homo sapiens 60344 R-HSA-189398 https://reactome.org/PathwayBrowser/#/R-HSA-189398 HMOX1 dimer, HMOX2 cleave heme TAS Homo sapiens 60344 R-HSA-189442 https://reactome.org/PathwayBrowser/#/R-HSA-189442 ALAS condenses SUCC-CoA and Gly to form dALA TAS Homo sapiens 60344 R-HSA-189465 https://reactome.org/PathwayBrowser/#/R-HSA-189465 FECH binds Fe2+ to PRIN9 to form heme TAS Homo sapiens 60344 R-HSA-198563 https://reactome.org/PathwayBrowser/#/R-HSA-198563 IDO1 dioxygenates L-Trp to NFK TAS Homo sapiens 60344 R-HSA-198824 https://reactome.org/PathwayBrowser/#/R-HSA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme TAS Homo sapiens 60344 R-HSA-198845 https://reactome.org/PathwayBrowser/#/R-HSA-198845 CYB5A:heme reduces Asc.- to AscH- TAS Homo sapiens 60344 R-HSA-202110 https://reactome.org/PathwayBrowser/#/R-HSA-202110 eNOS:Caveolin-1 complex binds to CaM TAS Homo sapiens 60344 R-HSA-202111 https://reactome.org/PathwayBrowser/#/R-HSA-202111 AKT1 phosphorylates eNOS TAS Homo sapiens 60344 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 60344 R-HSA-202129 https://reactome.org/PathwayBrowser/#/R-HSA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex TAS Homo sapiens 60344 R-HSA-202132 https://reactome.org/PathwayBrowser/#/R-HSA-202132 depalmitoylated eNOS translocates from plasma membrane TAS Homo sapiens 60344 R-HSA-202137 https://reactome.org/PathwayBrowser/#/R-HSA-202137 AKT1 binds eNOS complex via HSP90 TAS Homo sapiens 60344 R-HSA-202144 https://reactome.org/PathwayBrowser/#/R-HSA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex TAS Homo sapiens 60344 R-HSA-203553 https://reactome.org/PathwayBrowser/#/R-HSA-203553 eNOS binds NOSIP TAS Homo sapiens 60344 R-HSA-203565 https://reactome.org/PathwayBrowser/#/R-HSA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP TAS Homo sapiens 60344 R-HSA-203613 https://reactome.org/PathwayBrowser/#/R-HSA-203613 depalmitoylation of eNOS TAS Homo sapiens 60344 R-HSA-203625 https://reactome.org/PathwayBrowser/#/R-HSA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane TAS Homo sapiens 60344 R-HSA-203662 https://reactome.org/PathwayBrowser/#/R-HSA-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 TAS Homo sapiens 60344 R-HSA-203680 https://reactome.org/PathwayBrowser/#/R-HSA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments TAS Homo sapiens 60344 R-HSA-203700 https://reactome.org/PathwayBrowser/#/R-HSA-203700 eNOS translocation from Golgi to Caveolae TAS Homo sapiens 60344 R-HSA-203712 https://reactome.org/PathwayBrowser/#/R-HSA-203712 eNOS associates with Caveolin-1 TAS Homo sapiens 60344 R-HSA-203716 https://reactome.org/PathwayBrowser/#/R-HSA-203716 eNOS:Caveolin-1 complex binds to Nostrin TAS Homo sapiens 60344 R-HSA-2168883 https://reactome.org/PathwayBrowser/#/R-HSA-2168883 Haptoglobin:Hemoglobin binds CD163 TAS Homo sapiens 60344 R-HSA-2168885 https://reactome.org/PathwayBrowser/#/R-HSA-2168885 Haptoglobin binds Hemoglobin TAS Homo sapiens 60344 R-HSA-2168886 https://reactome.org/PathwayBrowser/#/R-HSA-2168886 Hemopexin binds Hemes TAS Homo sapiens 60344 R-HSA-2168889 https://reactome.org/PathwayBrowser/#/R-HSA-2168889 Haptoglobin-related Protein binds Hemoglobin TAS Homo sapiens 60344 R-HSA-2168897 https://reactome.org/PathwayBrowser/#/R-HSA-2168897 LRP1 (CD91) binds Hemopexin:heme TAS Homo sapiens 60344 R-HSA-2230938 https://reactome.org/PathwayBrowser/#/R-HSA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed TAS Homo sapiens 60344 R-HSA-2230983 https://reactome.org/PathwayBrowser/#/R-HSA-2230983 LRP1:Hemopexin:heme is endocytosed TAS Homo sapiens 60344 R-HSA-2408559 https://reactome.org/PathwayBrowser/#/R-HSA-2408559 SeHCys and Ser are dehydrated into SeCysta by CBS IEA Homo sapiens 60344 R-HSA-2995330 https://reactome.org/PathwayBrowser/#/R-HSA-2995330 COX10 transforms heme to heme O TAS Homo sapiens 60344 R-HSA-382560 https://reactome.org/PathwayBrowser/#/R-HSA-382560 ABC7, mABC1 and mABC2 mediate heme transport TAS Homo sapiens 60344 R-HSA-5218827 https://reactome.org/PathwayBrowser/#/R-HSA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 TAS Homo sapiens 60344 R-HSA-5218841 https://reactome.org/PathwayBrowser/#/R-HSA-5218841 NADPH oxidase 2 generates superoxide from oxygen TAS Homo sapiens 60344 R-HSA-5340214 https://reactome.org/PathwayBrowser/#/R-HSA-5340214 CYGB binds O2 TAS Homo sapiens 60344 R-HSA-5340226 https://reactome.org/PathwayBrowser/#/R-HSA-5340226 CYGB dioxygenates NO TAS Homo sapiens 60344 R-HSA-6806831 https://reactome.org/PathwayBrowser/#/R-HSA-6806831 CYB5Rs reduce MetHb to HbA TAS Homo sapiens 60344 R-HSA-71188 https://reactome.org/PathwayBrowser/#/R-HSA-71188 TDO tetramer dioxygenates L-Trp to NFK TAS Homo sapiens 60344 R-HSA-76031 https://reactome.org/PathwayBrowser/#/R-HSA-76031 2 H2O2 => O2 + 2 H2O TAS Homo sapiens 60344 R-HSA-888614 https://reactome.org/PathwayBrowser/#/R-HSA-888614 IDO2 dioxygenates L-Trp to NFK TAS Homo sapiens 60344 R-HSA-8981606 https://reactome.org/PathwayBrowser/#/R-HSA-8981606 Myoglobin binds oxygen TAS Homo sapiens 60344 R-HSA-8981610 https://reactome.org/PathwayBrowser/#/R-HSA-8981610 Neuroglobin binds oxygen TAS Homo sapiens 60344 R-HSA-8981621 https://reactome.org/PathwayBrowser/#/R-HSA-8981621 Neuroglobin:oxygen dissociates TAS Homo sapiens 60344 R-HSA-8981622 https://reactome.org/PathwayBrowser/#/R-HSA-8981622 Myoglobin:oxygen dissociates TAS Homo sapiens 60344 R-HSA-8982617 https://reactome.org/PathwayBrowser/#/R-HSA-8982617 CYGB:O2 dissociates TAS Homo sapiens 60344 R-HSA-9013145 https://reactome.org/PathwayBrowser/#/R-HSA-9013145 RAC1 binds effectors at the plasma membrane TAS Homo sapiens 60344 R-HSA-9018808 https://reactome.org/PathwayBrowser/#/R-HSA-9018808 RAC3 binds effectors at the plasma membrane TAS Homo sapiens 60344 R-HSA-917805 https://reactome.org/PathwayBrowser/#/R-HSA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ TAS Homo sapiens 60344 R-HSA-917870 https://reactome.org/PathwayBrowser/#/R-HSA-917870 SLC46A1 transports hemes from extracellular region to cytosol TAS Homo sapiens 60344 R-HSA-917892 https://reactome.org/PathwayBrowser/#/R-HSA-917892 FLVCR1-1 transports heme from cytosol to extracellular region TAS Homo sapiens 60344 R-HSA-917979 https://reactome.org/PathwayBrowser/#/R-HSA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region TAS Homo sapiens 60344 R-HSA-9661408 https://reactome.org/PathwayBrowser/#/R-HSA-9661408 FLVCR1-2 transports heme from mitochondrial matrix to cytosol TAS Homo sapiens 60344 R-HSA-9661419 https://reactome.org/PathwayBrowser/#/R-HSA-9661419 ALB binds extracellular heme TAS Homo sapiens 60344 R-HSA-9707504 https://reactome.org/PathwayBrowser/#/R-HSA-9707504 H2O2 oxidises ferrohemoglobin to MetHb TAS Homo sapiens 60344 R-HSA-9707505 https://reactome.org/PathwayBrowser/#/R-HSA-9707505 Hemes bind to CLEC1B dimer TAS Homo sapiens 60344 R-HSA-9707523 https://reactome.org/PathwayBrowser/#/R-HSA-9707523 Hemes bind to BACH1:MAFK TAS Homo sapiens 60344 R-HSA-9707586 https://reactome.org/PathwayBrowser/#/R-HSA-9707586 FeHM oxidises LDL,HDL TAS Homo sapiens 60344 R-HSA-9707594 https://reactome.org/PathwayBrowser/#/R-HSA-9707594 Hemes bind LY96 TAS Homo sapiens 60344 R-HSA-9707606 https://reactome.org/PathwayBrowser/#/R-HSA-9707606 PGRMC2:Hemes translocate to the nucleus TAS Homo sapiens 60344 R-HSA-9707659 https://reactome.org/PathwayBrowser/#/R-HSA-9707659 Hemes:LY96 activates TLR4 TAS Homo sapiens 60344 R-HSA-9707683 https://reactome.org/PathwayBrowser/#/R-HSA-9707683 PGRMC2 binds Hemes TAS Homo sapiens 60344 R-HSA-9707856 https://reactome.org/PathwayBrowser/#/R-HSA-9707856 PGRMC2:Hemes dissociates TAS Homo sapiens 60344 R-HSA-9708423 https://reactome.org/PathwayBrowser/#/R-HSA-9708423 XPO1:BACH1:Hemes are transported out of the nucleus TAS Homo sapiens 60344 R-HSA-9708430 https://reactome.org/PathwayBrowser/#/R-HSA-9708430 XPO1 (CRM1) binds to BACH1:Hemes TAS Homo sapiens 60344 R-HSA-9709317 https://reactome.org/PathwayBrowser/#/R-HSA-9709317 CO binds to free ferrohemoglobin TAS Homo sapiens 60344 R-HSA-9709360 https://reactome.org/PathwayBrowser/#/R-HSA-9709360 H2O2 reduces MetHb TAS Homo sapiens 60344 R-HSA-9756470 https://reactome.org/PathwayBrowser/#/R-HSA-9756470 N binds to heme TAS Homo sapiens 60344 R-HSA-9838035 https://reactome.org/PathwayBrowser/#/R-HSA-9838035 CLPXP binds mitochondrial matrix proteins TAS Homo sapiens 60344 R-HSA-9838289 https://reactome.org/PathwayBrowser/#/R-HSA-9838289 CLPXP degrades mitochondrial matrix proteins TAS Homo sapiens 60344 R-MMU-1222376 https://reactome.org/PathwayBrowser/#/R-MMU-1222376 NOX2 generates superoxide from oxygen IEA Mus musculus 60344 R-MMU-1237325 https://reactome.org/PathwayBrowser/#/R-MMU-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Mus musculus 60344 R-MMU-1247668 https://reactome.org/PathwayBrowser/#/R-MMU-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Mus musculus 60344 R-MMU-1497784 https://reactome.org/PathwayBrowser/#/R-MMU-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Mus musculus 60344 R-MMU-1497796 https://reactome.org/PathwayBrowser/#/R-MMU-1497796 BH2 binding can lead to eNOS uncoupling IEA Mus musculus 60344 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 60344 R-MMU-1614524 https://reactome.org/PathwayBrowser/#/R-MMU-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Mus musculus 60344 R-MMU-189398 https://reactome.org/PathwayBrowser/#/R-MMU-189398 HMOX1 dimer, HMOX2 cleave heme IEA Mus musculus 60344 R-MMU-189442 https://reactome.org/PathwayBrowser/#/R-MMU-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Mus musculus 60344 R-MMU-189465 https://reactome.org/PathwayBrowser/#/R-MMU-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Mus musculus 60344 R-MMU-198563 https://reactome.org/PathwayBrowser/#/R-MMU-198563 IDO1 dioxygenates L-Trp to NFK IEA Mus musculus 60344 R-MMU-198824 https://reactome.org/PathwayBrowser/#/R-MMU-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Mus musculus 60344 R-MMU-198845 https://reactome.org/PathwayBrowser/#/R-MMU-198845 CYB5A:heme reduces Asc.- to AscH- IEA Mus musculus 60344 R-MMU-202110 https://reactome.org/PathwayBrowser/#/R-MMU-202110 eNOS:Caveolin-1 complex binds to CaM IEA Mus musculus 60344 R-MMU-202111 https://reactome.org/PathwayBrowser/#/R-MMU-202111 AKT1 phosphorylates eNOS IEA Mus musculus 60344 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 60344 R-MMU-202129 https://reactome.org/PathwayBrowser/#/R-MMU-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Mus musculus 60344 R-MMU-202132 https://reactome.org/PathwayBrowser/#/R-MMU-202132 depalmitoylated eNOS translocates from plasma membrane IEA Mus musculus 60344 R-MMU-202137 https://reactome.org/PathwayBrowser/#/R-MMU-202137 AKT1 binds eNOS complex via HSP90 IEA Mus musculus 60344 R-MMU-202144 https://reactome.org/PathwayBrowser/#/R-MMU-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Mus musculus 60344 R-MMU-203553 https://reactome.org/PathwayBrowser/#/R-MMU-203553 eNOS binds NOSIP IEA Mus musculus 60344 R-MMU-203613 https://reactome.org/PathwayBrowser/#/R-MMU-203613 depalmitoylation of eNOS IEA Mus musculus 60344 R-MMU-203625 https://reactome.org/PathwayBrowser/#/R-MMU-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Mus musculus 60344 R-MMU-203662 https://reactome.org/PathwayBrowser/#/R-MMU-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Mus musculus 60344 R-MMU-203680 https://reactome.org/PathwayBrowser/#/R-MMU-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Mus musculus 60344 R-MMU-203700 https://reactome.org/PathwayBrowser/#/R-MMU-203700 eNOS translocation from Golgi to Caveolae IEA Mus musculus 60344 R-MMU-203712 https://reactome.org/PathwayBrowser/#/R-MMU-203712 eNOS associates with Caveolin-1 IEA Mus musculus 60344 R-MMU-203716 https://reactome.org/PathwayBrowser/#/R-MMU-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Mus musculus 60344 R-MMU-2168883 https://reactome.org/PathwayBrowser/#/R-MMU-2168883 Haptoglobin:Hemoglobin binds CD163 IEA Mus musculus 60344 R-MMU-2168885 https://reactome.org/PathwayBrowser/#/R-MMU-2168885 Haptoglobin binds Hemoglobin IEA Mus musculus 60344 R-MMU-2168886 https://reactome.org/PathwayBrowser/#/R-MMU-2168886 Hemopexin binds Hemes IEA Mus musculus 60344 R-MMU-2168889 https://reactome.org/PathwayBrowser/#/R-MMU-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Mus musculus 60344 R-MMU-2168897 https://reactome.org/PathwayBrowser/#/R-MMU-2168897 LRP1 (CD91) binds Hemopexin:heme IEA Mus musculus 60344 R-MMU-2230938 https://reactome.org/PathwayBrowser/#/R-MMU-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Mus musculus 60344 R-MMU-2230983 https://reactome.org/PathwayBrowser/#/R-MMU-2230983 LRP1:Hemopexin:heme is endocytosed IEA Mus musculus 60344 R-MMU-2995330 https://reactome.org/PathwayBrowser/#/R-MMU-2995330 COX10 transforms heme to heme O IEA Mus musculus 60344 R-MMU-382560 https://reactome.org/PathwayBrowser/#/R-MMU-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Mus musculus 60344 R-MMU-5218827 https://reactome.org/PathwayBrowser/#/R-MMU-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Mus musculus 60344 R-MMU-5218841 https://reactome.org/PathwayBrowser/#/R-MMU-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Mus musculus 60344 R-MMU-5340214 https://reactome.org/PathwayBrowser/#/R-MMU-5340214 CYGB binds O2 IEA Mus musculus 60344 R-MMU-5340226 https://reactome.org/PathwayBrowser/#/R-MMU-5340226 CYGB dioxygenates NO IEA Mus musculus 60344 R-MMU-6806831 https://reactome.org/PathwayBrowser/#/R-MMU-6806831 CYB5Rs reduce MetHb to HbA IEA Mus musculus 60344 R-MMU-71188 https://reactome.org/PathwayBrowser/#/R-MMU-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Mus musculus 60344 R-MMU-76031 https://reactome.org/PathwayBrowser/#/R-MMU-76031 2 H2O2 => O2 + 2 H2O IEA Mus musculus 60344 R-MMU-888614 https://reactome.org/PathwayBrowser/#/R-MMU-888614 IDO2 dioxygenates L-Trp to NFK IEA Mus musculus 60344 R-MMU-8981606 https://reactome.org/PathwayBrowser/#/R-MMU-8981606 Myoglobin binds oxygen IEA Mus musculus 60344 R-MMU-8981610 https://reactome.org/PathwayBrowser/#/R-MMU-8981610 Neuroglobin binds oxygen IEA Mus musculus 60344 R-MMU-8981621 https://reactome.org/PathwayBrowser/#/R-MMU-8981621 Neuroglobin:oxygen dissociates IEA Mus musculus 60344 R-MMU-8981622 https://reactome.org/PathwayBrowser/#/R-MMU-8981622 Myoglobin:oxygen dissociates IEA Mus musculus 60344 R-MMU-8982617 https://reactome.org/PathwayBrowser/#/R-MMU-8982617 CYGB:O2 dissociates IEA Mus musculus 60344 R-MMU-9013145 https://reactome.org/PathwayBrowser/#/R-MMU-9013145 RAC1 binds effectors at the plasma membrane IEA Mus musculus 60344 R-MMU-9018808 https://reactome.org/PathwayBrowser/#/R-MMU-9018808 RAC3 binds effectors at the plasma membrane IEA Mus musculus 60344 R-MMU-917805 https://reactome.org/PathwayBrowser/#/R-MMU-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Mus musculus 60344 R-MMU-917870 https://reactome.org/PathwayBrowser/#/R-MMU-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Mus musculus 60344 R-MMU-917892 https://reactome.org/PathwayBrowser/#/R-MMU-917892 FLVCR1-1 transports heme from cytosol to extracellular region IEA Mus musculus 60344 R-MMU-917979 https://reactome.org/PathwayBrowser/#/R-MMU-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Mus musculus 60344 R-MMU-9661408 https://reactome.org/PathwayBrowser/#/R-MMU-9661408 FLVCR1-2 transports heme from mitochondrial matrix to cytosol IEA Mus musculus 60344 R-MMU-9661419 https://reactome.org/PathwayBrowser/#/R-MMU-9661419 ALB binds extracellular heme IEA Mus musculus 60344 R-MMU-9707504 https://reactome.org/PathwayBrowser/#/R-MMU-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Mus musculus 60344 R-MMU-9707505 https://reactome.org/PathwayBrowser/#/R-MMU-9707505 Hemes bind to CLEC1B dimer IEA Mus musculus 60344 R-MMU-9707523 https://reactome.org/PathwayBrowser/#/R-MMU-9707523 Hemes bind to BACH1:MAFK IEA Mus musculus 60344 R-MMU-9707586 https://reactome.org/PathwayBrowser/#/R-MMU-9707586 FeHM oxidises LDL,HDL IEA Mus musculus 60344 R-MMU-9707594 https://reactome.org/PathwayBrowser/#/R-MMU-9707594 Hemes bind LY96 IEA Mus musculus 60344 R-MMU-9707606 https://reactome.org/PathwayBrowser/#/R-MMU-9707606 PGRMC2:Hemes translocate to the nucleus IEA Mus musculus 60344 R-MMU-9707659 https://reactome.org/PathwayBrowser/#/R-MMU-9707659 Hemes:LY96 activates TLR4 IEA Mus musculus 60344 R-MMU-9707683 https://reactome.org/PathwayBrowser/#/R-MMU-9707683 PGRMC2 binds Hemes IEA Mus musculus 60344 R-MMU-9707856 https://reactome.org/PathwayBrowser/#/R-MMU-9707856 PGRMC2:Hemes dissociates IEA Mus musculus 60344 R-MMU-9708423 https://reactome.org/PathwayBrowser/#/R-MMU-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Mus musculus 60344 R-MMU-9708430 https://reactome.org/PathwayBrowser/#/R-MMU-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Mus musculus 60344 R-MMU-9709317 https://reactome.org/PathwayBrowser/#/R-MMU-9709317 CO binds to free ferrohemoglobin IEA Mus musculus 60344 R-MMU-9709360 https://reactome.org/PathwayBrowser/#/R-MMU-9709360 H2O2 reduces MetHb IEA Mus musculus 60344 R-MMU-9838035 https://reactome.org/PathwayBrowser/#/R-MMU-9838035 CLPXP binds mitochondrial matrix proteins IEA Mus musculus 60344 R-MMU-9838289 https://reactome.org/PathwayBrowser/#/R-MMU-9838289 CLPXP degrades mitochondrial matrix proteins IEA Mus musculus 60344 R-PFA-1497784 https://reactome.org/PathwayBrowser/#/R-PFA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Plasmodium falciparum 60344 R-PFA-1497796 https://reactome.org/PathwayBrowser/#/R-PFA-1497796 BH2 binding can lead to eNOS uncoupling IEA Plasmodium falciparum 60344 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 60344 R-PFA-189442 https://reactome.org/PathwayBrowser/#/R-PFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Plasmodium falciparum 60344 R-PFA-189465 https://reactome.org/PathwayBrowser/#/R-PFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Plasmodium falciparum 60344 R-PFA-202111 https://reactome.org/PathwayBrowser/#/R-PFA-202111 AKT1 phosphorylates eNOS IEA Plasmodium falciparum 60344 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 60344 R-PFA-202132 https://reactome.org/PathwayBrowser/#/R-PFA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Plasmodium falciparum 60344 R-PFA-203553 https://reactome.org/PathwayBrowser/#/R-PFA-203553 eNOS binds NOSIP IEA Plasmodium falciparum 60344 R-PFA-203680 https://reactome.org/PathwayBrowser/#/R-PFA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Plasmodium falciparum 60344 R-PFA-203700 https://reactome.org/PathwayBrowser/#/R-PFA-203700 eNOS translocation from Golgi to Caveolae IEA Plasmodium falciparum 60344 R-PFA-2995330 https://reactome.org/PathwayBrowser/#/R-PFA-2995330 COX10 transforms heme to heme O IEA Plasmodium falciparum 60344 R-PFA-917979 https://reactome.org/PathwayBrowser/#/R-PFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Plasmodium falciparum 60344 R-RNO-1222376 https://reactome.org/PathwayBrowser/#/R-RNO-1222376 NOX2 generates superoxide from oxygen IEA Rattus norvegicus 60344 R-RNO-1237325 https://reactome.org/PathwayBrowser/#/R-RNO-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Rattus norvegicus 60344 R-RNO-1247668 https://reactome.org/PathwayBrowser/#/R-RNO-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Rattus norvegicus 60344 R-RNO-1497784 https://reactome.org/PathwayBrowser/#/R-RNO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Rattus norvegicus 60344 R-RNO-1497796 https://reactome.org/PathwayBrowser/#/R-RNO-1497796 BH2 binding can lead to eNOS uncoupling IEA Rattus norvegicus 60344 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 60344 R-RNO-1614524 https://reactome.org/PathwayBrowser/#/R-RNO-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Rattus norvegicus 60344 R-RNO-189398 https://reactome.org/PathwayBrowser/#/R-RNO-189398 HMOX1 dimer, HMOX2 cleave heme IEA Rattus norvegicus 60344 R-RNO-189442 https://reactome.org/PathwayBrowser/#/R-RNO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Rattus norvegicus 60344 R-RNO-189465 https://reactome.org/PathwayBrowser/#/R-RNO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Rattus norvegicus 60344 R-RNO-198563 https://reactome.org/PathwayBrowser/#/R-RNO-198563 IDO1 dioxygenates L-Trp to NFK IEA Rattus norvegicus 60344 R-RNO-198824 https://reactome.org/PathwayBrowser/#/R-RNO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Rattus norvegicus 60344 R-RNO-198845 https://reactome.org/PathwayBrowser/#/R-RNO-198845 CYB5A:heme reduces Asc.- to AscH- IEA Rattus norvegicus 60344 R-RNO-202110 https://reactome.org/PathwayBrowser/#/R-RNO-202110 eNOS:Caveolin-1 complex binds to CaM IEA Rattus norvegicus 60344 R-RNO-202111 https://reactome.org/PathwayBrowser/#/R-RNO-202111 AKT1 phosphorylates eNOS IEA Rattus norvegicus 60344 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 60344 R-RNO-202129 https://reactome.org/PathwayBrowser/#/R-RNO-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Rattus norvegicus 60344 R-RNO-202132 https://reactome.org/PathwayBrowser/#/R-RNO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Rattus norvegicus 60344 R-RNO-202137 https://reactome.org/PathwayBrowser/#/R-RNO-202137 AKT1 binds eNOS complex via HSP90 IEA Rattus norvegicus 60344 R-RNO-202144 https://reactome.org/PathwayBrowser/#/R-RNO-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Rattus norvegicus 60344 R-RNO-203553 https://reactome.org/PathwayBrowser/#/R-RNO-203553 eNOS binds NOSIP IEA Rattus norvegicus 60344 R-RNO-203613 https://reactome.org/PathwayBrowser/#/R-RNO-203613 depalmitoylation of eNOS IEA Rattus norvegicus 60344 R-RNO-203625 https://reactome.org/PathwayBrowser/#/R-RNO-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Rattus norvegicus 60344 R-RNO-203662 https://reactome.org/PathwayBrowser/#/R-RNO-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Rattus norvegicus 60344 R-RNO-203680 https://reactome.org/PathwayBrowser/#/R-RNO-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Rattus norvegicus 60344 R-RNO-203700 https://reactome.org/PathwayBrowser/#/R-RNO-203700 eNOS translocation from Golgi to Caveolae IEA Rattus norvegicus 60344 R-RNO-203712 https://reactome.org/PathwayBrowser/#/R-RNO-203712 eNOS associates with Caveolin-1 IEA Rattus norvegicus 60344 R-RNO-203716 https://reactome.org/PathwayBrowser/#/R-RNO-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Rattus norvegicus 60344 R-RNO-2168883 https://reactome.org/PathwayBrowser/#/R-RNO-2168883 Haptoglobin:Hemoglobin binds CD163 IEA Rattus norvegicus 60344 R-RNO-2168885 https://reactome.org/PathwayBrowser/#/R-RNO-2168885 Haptoglobin binds Hemoglobin IEA Rattus norvegicus 60344 R-RNO-2168886 https://reactome.org/PathwayBrowser/#/R-RNO-2168886 Hemopexin binds Hemes IEA Rattus norvegicus 60344 R-RNO-2168889 https://reactome.org/PathwayBrowser/#/R-RNO-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Rattus norvegicus 60344 R-RNO-2168897 https://reactome.org/PathwayBrowser/#/R-RNO-2168897 LRP1 (CD91) binds Hemopexin:heme IEA Rattus norvegicus 60344 R-RNO-2230938 https://reactome.org/PathwayBrowser/#/R-RNO-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Rattus norvegicus 60344 R-RNO-2230983 https://reactome.org/PathwayBrowser/#/R-RNO-2230983 LRP1:Hemopexin:heme is endocytosed IEA Rattus norvegicus 60344 R-RNO-2408533 https://reactome.org/PathwayBrowser/#/R-RNO-2408533 SeHCys and Ser are dehydrated into SeCysta by Cbs TAS Rattus norvegicus 60344 R-RNO-2995330 https://reactome.org/PathwayBrowser/#/R-RNO-2995330 COX10 transforms heme to heme O IEA Rattus norvegicus 60344 R-RNO-382560 https://reactome.org/PathwayBrowser/#/R-RNO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Rattus norvegicus 60344 R-RNO-5218827 https://reactome.org/PathwayBrowser/#/R-RNO-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Rattus norvegicus 60344 R-RNO-5218841 https://reactome.org/PathwayBrowser/#/R-RNO-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Rattus norvegicus 60344 R-RNO-5340214 https://reactome.org/PathwayBrowser/#/R-RNO-5340214 CYGB binds O2 IEA Rattus norvegicus 60344 R-RNO-5340226 https://reactome.org/PathwayBrowser/#/R-RNO-5340226 CYGB dioxygenates NO IEA Rattus norvegicus 60344 R-RNO-6806831 https://reactome.org/PathwayBrowser/#/R-RNO-6806831 CYB5Rs reduce MetHb to HbA IEA Rattus norvegicus 60344 R-RNO-71188 https://reactome.org/PathwayBrowser/#/R-RNO-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Rattus norvegicus 60344 R-RNO-76031 https://reactome.org/PathwayBrowser/#/R-RNO-76031 2 H2O2 => O2 + 2 H2O IEA Rattus norvegicus 60344 R-RNO-888614 https://reactome.org/PathwayBrowser/#/R-RNO-888614 IDO2 dioxygenates L-Trp to NFK IEA Rattus norvegicus 60344 R-RNO-8981606 https://reactome.org/PathwayBrowser/#/R-RNO-8981606 Myoglobin binds oxygen IEA Rattus norvegicus 60344 R-RNO-8981610 https://reactome.org/PathwayBrowser/#/R-RNO-8981610 Neuroglobin binds oxygen IEA Rattus norvegicus 60344 R-RNO-8981621 https://reactome.org/PathwayBrowser/#/R-RNO-8981621 Neuroglobin:oxygen dissociates IEA Rattus norvegicus 60344 R-RNO-8981622 https://reactome.org/PathwayBrowser/#/R-RNO-8981622 Myoglobin:oxygen dissociates IEA Rattus norvegicus 60344 R-RNO-8982617 https://reactome.org/PathwayBrowser/#/R-RNO-8982617 CYGB:O2 dissociates IEA Rattus norvegicus 60344 R-RNO-9013145 https://reactome.org/PathwayBrowser/#/R-RNO-9013145 RAC1 binds effectors at the plasma membrane IEA Rattus norvegicus 60344 R-RNO-917805 https://reactome.org/PathwayBrowser/#/R-RNO-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Rattus norvegicus 60344 R-RNO-917870 https://reactome.org/PathwayBrowser/#/R-RNO-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Rattus norvegicus 60344 R-RNO-917979 https://reactome.org/PathwayBrowser/#/R-RNO-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Rattus norvegicus 60344 R-RNO-9661419 https://reactome.org/PathwayBrowser/#/R-RNO-9661419 ALB binds extracellular heme IEA Rattus norvegicus 60344 R-RNO-9707504 https://reactome.org/PathwayBrowser/#/R-RNO-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Rattus norvegicus 60344 R-RNO-9707505 https://reactome.org/PathwayBrowser/#/R-RNO-9707505 Hemes bind to CLEC1B dimer IEA Rattus norvegicus 60344 R-RNO-9707586 https://reactome.org/PathwayBrowser/#/R-RNO-9707586 FeHM oxidises LDL,HDL IEA Rattus norvegicus 60344 R-RNO-9707594 https://reactome.org/PathwayBrowser/#/R-RNO-9707594 Hemes bind LY96 IEA Rattus norvegicus 60344 R-RNO-9707606 https://reactome.org/PathwayBrowser/#/R-RNO-9707606 PGRMC2:Hemes translocate to the nucleus IEA Rattus norvegicus 60344 R-RNO-9707659 https://reactome.org/PathwayBrowser/#/R-RNO-9707659 Hemes:LY96 activates TLR4 IEA Rattus norvegicus 60344 R-RNO-9707683 https://reactome.org/PathwayBrowser/#/R-RNO-9707683 PGRMC2 binds Hemes IEA Rattus norvegicus 60344 R-RNO-9707856 https://reactome.org/PathwayBrowser/#/R-RNO-9707856 PGRMC2:Hemes dissociates IEA Rattus norvegicus 60344 R-RNO-9708423 https://reactome.org/PathwayBrowser/#/R-RNO-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Rattus norvegicus 60344 R-RNO-9708430 https://reactome.org/PathwayBrowser/#/R-RNO-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Rattus norvegicus 60344 R-RNO-9709317 https://reactome.org/PathwayBrowser/#/R-RNO-9709317 CO binds to free ferrohemoglobin IEA Rattus norvegicus 60344 R-RNO-9709360 https://reactome.org/PathwayBrowser/#/R-RNO-9709360 H2O2 reduces MetHb IEA Rattus norvegicus 60344 R-RNO-9838035 https://reactome.org/PathwayBrowser/#/R-RNO-9838035 CLPXP binds mitochondrial matrix proteins IEA Rattus norvegicus 60344 R-RNO-9838289 https://reactome.org/PathwayBrowser/#/R-RNO-9838289 CLPXP degrades mitochondrial matrix proteins IEA Rattus norvegicus 60344 R-SCE-1497784 https://reactome.org/PathwayBrowser/#/R-SCE-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Saccharomyces cerevisiae 60344 R-SCE-1497796 https://reactome.org/PathwayBrowser/#/R-SCE-1497796 BH2 binding can lead to eNOS uncoupling IEA Saccharomyces cerevisiae 60344 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 60344 R-SCE-1614524 https://reactome.org/PathwayBrowser/#/R-SCE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Saccharomyces cerevisiae 60344 R-SCE-189442 https://reactome.org/PathwayBrowser/#/R-SCE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Saccharomyces cerevisiae 60344 R-SCE-189465 https://reactome.org/PathwayBrowser/#/R-SCE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Saccharomyces cerevisiae 60344 R-SCE-198563 https://reactome.org/PathwayBrowser/#/R-SCE-198563 IDO1 dioxygenates L-Trp to NFK IEA Saccharomyces cerevisiae 60344 R-SCE-198824 https://reactome.org/PathwayBrowser/#/R-SCE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Saccharomyces cerevisiae 60344 R-SCE-198845 https://reactome.org/PathwayBrowser/#/R-SCE-198845 CYB5A:heme reduces Asc.- to AscH- IEA Saccharomyces cerevisiae 60344 R-SCE-202111 https://reactome.org/PathwayBrowser/#/R-SCE-202111 AKT1 phosphorylates eNOS IEA Saccharomyces cerevisiae 60344 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 60344 R-SCE-202132 https://reactome.org/PathwayBrowser/#/R-SCE-202132 depalmitoylated eNOS translocates from plasma membrane IEA Saccharomyces cerevisiae 60344 R-SCE-203613 https://reactome.org/PathwayBrowser/#/R-SCE-203613 depalmitoylation of eNOS IEA Saccharomyces cerevisiae 60344 R-SCE-203700 https://reactome.org/PathwayBrowser/#/R-SCE-203700 eNOS translocation from Golgi to Caveolae IEA Saccharomyces cerevisiae 60344 R-SCE-2995330 https://reactome.org/PathwayBrowser/#/R-SCE-2995330 COX10 transforms heme to heme O IEA Saccharomyces cerevisiae 60344 R-SCE-382560 https://reactome.org/PathwayBrowser/#/R-SCE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Saccharomyces cerevisiae 60344 R-SCE-76031 https://reactome.org/PathwayBrowser/#/R-SCE-76031 2 H2O2 => O2 + 2 H2O IEA Saccharomyces cerevisiae 60344 R-SCE-888614 https://reactome.org/PathwayBrowser/#/R-SCE-888614 IDO2 dioxygenates L-Trp to NFK IEA Saccharomyces cerevisiae 60344 R-SCE-917870 https://reactome.org/PathwayBrowser/#/R-SCE-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Saccharomyces cerevisiae 60344 R-SCE-917979 https://reactome.org/PathwayBrowser/#/R-SCE-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Saccharomyces cerevisiae 60344 R-SCE-9707606 https://reactome.org/PathwayBrowser/#/R-SCE-9707606 PGRMC2:Hemes translocate to the nucleus IEA Saccharomyces cerevisiae 60344 R-SCE-9707683 https://reactome.org/PathwayBrowser/#/R-SCE-9707683 PGRMC2 binds Hemes IEA Saccharomyces cerevisiae 60344 R-SCE-9707856 https://reactome.org/PathwayBrowser/#/R-SCE-9707856 PGRMC2:Hemes dissociates IEA Saccharomyces cerevisiae 60344 R-SPO-1497784 https://reactome.org/PathwayBrowser/#/R-SPO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Schizosaccharomyces pombe 60344 R-SPO-1497796 https://reactome.org/PathwayBrowser/#/R-SPO-1497796 BH2 binding can lead to eNOS uncoupling IEA Schizosaccharomyces pombe 60344 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 60344 R-SPO-189442 https://reactome.org/PathwayBrowser/#/R-SPO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Schizosaccharomyces pombe 60344 R-SPO-189465 https://reactome.org/PathwayBrowser/#/R-SPO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Schizosaccharomyces pombe 60344 R-SPO-198824 https://reactome.org/PathwayBrowser/#/R-SPO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Schizosaccharomyces pombe 60344 R-SPO-198845 https://reactome.org/PathwayBrowser/#/R-SPO-198845 CYB5A:heme reduces Asc.- to AscH- IEA Schizosaccharomyces pombe 60344 R-SPO-202111 https://reactome.org/PathwayBrowser/#/R-SPO-202111 AKT1 phosphorylates eNOS IEA Schizosaccharomyces pombe 60344 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 60344 R-SPO-202132 https://reactome.org/PathwayBrowser/#/R-SPO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Schizosaccharomyces pombe 60344 R-SPO-202137 https://reactome.org/PathwayBrowser/#/R-SPO-202137 AKT1 binds eNOS complex via HSP90 IEA Schizosaccharomyces pombe 60344 R-SPO-203613 https://reactome.org/PathwayBrowser/#/R-SPO-203613 depalmitoylation of eNOS IEA Schizosaccharomyces pombe 60344 R-SPO-203700 https://reactome.org/PathwayBrowser/#/R-SPO-203700 eNOS translocation from Golgi to Caveolae IEA Schizosaccharomyces pombe 60344 R-SPO-2995330 https://reactome.org/PathwayBrowser/#/R-SPO-2995330 COX10 transforms heme to heme O IEA Schizosaccharomyces pombe 60344 R-SPO-382560 https://reactome.org/PathwayBrowser/#/R-SPO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Schizosaccharomyces pombe 60344 R-SPO-76031 https://reactome.org/PathwayBrowser/#/R-SPO-76031 2 H2O2 => O2 + 2 H2O IEA Schizosaccharomyces pombe 60344 R-SPO-917870 https://reactome.org/PathwayBrowser/#/R-SPO-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Schizosaccharomyces pombe 60344 R-SPO-9707606 https://reactome.org/PathwayBrowser/#/R-SPO-9707606 PGRMC2:Hemes translocate to the nucleus IEA Schizosaccharomyces pombe 60344 R-SPO-9707683 https://reactome.org/PathwayBrowser/#/R-SPO-9707683 PGRMC2 binds Hemes IEA Schizosaccharomyces pombe 60344 R-SPO-9707856 https://reactome.org/PathwayBrowser/#/R-SPO-9707856 PGRMC2:Hemes dissociates IEA Schizosaccharomyces pombe 60344 R-SSC-1222376 https://reactome.org/PathwayBrowser/#/R-SSC-1222376 NOX2 generates superoxide from oxygen IEA Sus scrofa 60344 R-SSC-1237325 https://reactome.org/PathwayBrowser/#/R-SSC-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Sus scrofa 60344 R-SSC-1247668 https://reactome.org/PathwayBrowser/#/R-SSC-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Sus scrofa 60344 R-SSC-1497784 https://reactome.org/PathwayBrowser/#/R-SSC-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Sus scrofa 60344 R-SSC-1497796 https://reactome.org/PathwayBrowser/#/R-SSC-1497796 BH2 binding can lead to eNOS uncoupling IEA Sus scrofa 60344 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 60344 R-SSC-1614524 https://reactome.org/PathwayBrowser/#/R-SSC-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Sus scrofa 60344 R-SSC-189398 https://reactome.org/PathwayBrowser/#/R-SSC-189398 HMOX1 dimer, HMOX2 cleave heme IEA Sus scrofa 60344 R-SSC-189442 https://reactome.org/PathwayBrowser/#/R-SSC-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Sus scrofa 60344 R-SSC-189465 https://reactome.org/PathwayBrowser/#/R-SSC-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Sus scrofa 60344 R-SSC-198563 https://reactome.org/PathwayBrowser/#/R-SSC-198563 IDO1 dioxygenates L-Trp to NFK IEA Sus scrofa 60344 R-SSC-198824 https://reactome.org/PathwayBrowser/#/R-SSC-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Sus scrofa 60344 R-SSC-198845 https://reactome.org/PathwayBrowser/#/R-SSC-198845 CYB5A:heme reduces Asc.- to AscH- IEA Sus scrofa 60344 R-SSC-202110 https://reactome.org/PathwayBrowser/#/R-SSC-202110 eNOS:Caveolin-1 complex binds to CaM IEA Sus scrofa 60344 R-SSC-202111 https://reactome.org/PathwayBrowser/#/R-SSC-202111 AKT1 phosphorylates eNOS IEA Sus scrofa 60344 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 60344 R-SSC-202129 https://reactome.org/PathwayBrowser/#/R-SSC-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Sus scrofa 60344 R-SSC-202132 https://reactome.org/PathwayBrowser/#/R-SSC-202132 depalmitoylated eNOS translocates from plasma membrane IEA Sus scrofa 60344 R-SSC-202144 https://reactome.org/PathwayBrowser/#/R-SSC-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Sus scrofa 60344 R-SSC-203553 https://reactome.org/PathwayBrowser/#/R-SSC-203553 eNOS binds NOSIP IEA Sus scrofa 60344 R-SSC-203565 https://reactome.org/PathwayBrowser/#/R-SSC-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Sus scrofa 60344 R-SSC-203613 https://reactome.org/PathwayBrowser/#/R-SSC-203613 depalmitoylation of eNOS IEA Sus scrofa 60344 R-SSC-203625 https://reactome.org/PathwayBrowser/#/R-SSC-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Sus scrofa 60344 R-SSC-203662 https://reactome.org/PathwayBrowser/#/R-SSC-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Sus scrofa 60344 R-SSC-203680 https://reactome.org/PathwayBrowser/#/R-SSC-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Sus scrofa 60344 R-SSC-203700 https://reactome.org/PathwayBrowser/#/R-SSC-203700 eNOS translocation from Golgi to Caveolae IEA Sus scrofa 60344 R-SSC-203712 https://reactome.org/PathwayBrowser/#/R-SSC-203712 eNOS associates with Caveolin-1 IEA Sus scrofa 60344 R-SSC-203716 https://reactome.org/PathwayBrowser/#/R-SSC-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Sus scrofa 60344 R-SSC-2168883 https://reactome.org/PathwayBrowser/#/R-SSC-2168883 Haptoglobin:Hemoglobin binds CD163 IEA Sus scrofa 60344 R-SSC-2168885 https://reactome.org/PathwayBrowser/#/R-SSC-2168885 Haptoglobin binds Hemoglobin IEA Sus scrofa 60344 R-SSC-2168886 https://reactome.org/PathwayBrowser/#/R-SSC-2168886 Hemopexin binds Hemes IEA Sus scrofa 60344 R-SSC-2168889 https://reactome.org/PathwayBrowser/#/R-SSC-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Sus scrofa 60344 R-SSC-2230938 https://reactome.org/PathwayBrowser/#/R-SSC-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Sus scrofa 60344 R-SSC-2995330 https://reactome.org/PathwayBrowser/#/R-SSC-2995330 COX10 transforms heme to heme O IEA Sus scrofa 60344 R-SSC-382560 https://reactome.org/PathwayBrowser/#/R-SSC-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Sus scrofa 60344 R-SSC-5218827 https://reactome.org/PathwayBrowser/#/R-SSC-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Sus scrofa 60344 R-SSC-5218841 https://reactome.org/PathwayBrowser/#/R-SSC-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Sus scrofa 60344 R-SSC-5340214 https://reactome.org/PathwayBrowser/#/R-SSC-5340214 CYGB binds O2 IEA Sus scrofa 60344 R-SSC-5340226 https://reactome.org/PathwayBrowser/#/R-SSC-5340226 CYGB dioxygenates NO IEA Sus scrofa 60344 R-SSC-6806831 https://reactome.org/PathwayBrowser/#/R-SSC-6806831 CYB5Rs reduce MetHb to HbA IEA Sus scrofa 60344 R-SSC-71188 https://reactome.org/PathwayBrowser/#/R-SSC-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Sus scrofa 60344 R-SSC-76031 https://reactome.org/PathwayBrowser/#/R-SSC-76031 2 H2O2 => O2 + 2 H2O IEA Sus scrofa 60344 R-SSC-888614 https://reactome.org/PathwayBrowser/#/R-SSC-888614 IDO2 dioxygenates L-Trp to NFK IEA Sus scrofa 60344 R-SSC-8981606 https://reactome.org/PathwayBrowser/#/R-SSC-8981606 Myoglobin binds oxygen IEA Sus scrofa 60344 R-SSC-8981610 https://reactome.org/PathwayBrowser/#/R-SSC-8981610 Neuroglobin binds oxygen IEA Sus scrofa 60344 R-SSC-8981621 https://reactome.org/PathwayBrowser/#/R-SSC-8981621 Neuroglobin:oxygen dissociates IEA Sus scrofa 60344 R-SSC-8981622 https://reactome.org/PathwayBrowser/#/R-SSC-8981622 Myoglobin:oxygen dissociates IEA Sus scrofa 60344 R-SSC-8982617 https://reactome.org/PathwayBrowser/#/R-SSC-8982617 CYGB:O2 dissociates IEA Sus scrofa 60344 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa 60344 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa 60344 R-SSC-917805 https://reactome.org/PathwayBrowser/#/R-SSC-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Sus scrofa 60344 R-SSC-917870 https://reactome.org/PathwayBrowser/#/R-SSC-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Sus scrofa 60344 R-SSC-917892 https://reactome.org/PathwayBrowser/#/R-SSC-917892 FLVCR1-1 transports heme from cytosol to extracellular region IEA Sus scrofa 60344 R-SSC-917979 https://reactome.org/PathwayBrowser/#/R-SSC-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Sus scrofa 60344 R-SSC-9661408 https://reactome.org/PathwayBrowser/#/R-SSC-9661408 FLVCR1-2 transports heme from mitochondrial matrix to cytosol IEA Sus scrofa 60344 R-SSC-9661419 https://reactome.org/PathwayBrowser/#/R-SSC-9661419 ALB binds extracellular heme IEA Sus scrofa 60344 R-SSC-9707504 https://reactome.org/PathwayBrowser/#/R-SSC-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Sus scrofa 60344 R-SSC-9707505 https://reactome.org/PathwayBrowser/#/R-SSC-9707505 Hemes bind to CLEC1B dimer IEA Sus scrofa 60344 R-SSC-9707523 https://reactome.org/PathwayBrowser/#/R-SSC-9707523 Hemes bind to BACH1:MAFK IEA Sus scrofa 60344 R-SSC-9707586 https://reactome.org/PathwayBrowser/#/R-SSC-9707586 FeHM oxidises LDL,HDL IEA Sus scrofa 60344 R-SSC-9707594 https://reactome.org/PathwayBrowser/#/R-SSC-9707594 Hemes bind LY96 IEA Sus scrofa 60344 R-SSC-9707606 https://reactome.org/PathwayBrowser/#/R-SSC-9707606 PGRMC2:Hemes translocate to the nucleus IEA Sus scrofa 60344 R-SSC-9707659 https://reactome.org/PathwayBrowser/#/R-SSC-9707659 Hemes:LY96 activates TLR4 IEA Sus scrofa 60344 R-SSC-9707683 https://reactome.org/PathwayBrowser/#/R-SSC-9707683 PGRMC2 binds Hemes IEA Sus scrofa 60344 R-SSC-9707856 https://reactome.org/PathwayBrowser/#/R-SSC-9707856 PGRMC2:Hemes dissociates IEA Sus scrofa 60344 R-SSC-9708423 https://reactome.org/PathwayBrowser/#/R-SSC-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Sus scrofa 60344 R-SSC-9708430 https://reactome.org/PathwayBrowser/#/R-SSC-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Sus scrofa 60344 R-SSC-9709317 https://reactome.org/PathwayBrowser/#/R-SSC-9709317 CO binds to free ferrohemoglobin IEA Sus scrofa 60344 R-SSC-9709360 https://reactome.org/PathwayBrowser/#/R-SSC-9709360 H2O2 reduces MetHb IEA Sus scrofa 60344 R-SSC-9838035 https://reactome.org/PathwayBrowser/#/R-SSC-9838035 CLPXP binds mitochondrial matrix proteins IEA Sus scrofa 60344 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa 60344 R-XTR-1222376 https://reactome.org/PathwayBrowser/#/R-XTR-1222376 NOX2 generates superoxide from oxygen IEA Xenopus tropicalis 60344 R-XTR-1237325 https://reactome.org/PathwayBrowser/#/R-XTR-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Xenopus tropicalis 60344 R-XTR-1247668 https://reactome.org/PathwayBrowser/#/R-XTR-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Xenopus tropicalis 60344 R-XTR-189398 https://reactome.org/PathwayBrowser/#/R-XTR-189398 HMOX1 dimer, HMOX2 cleave heme IEA Xenopus tropicalis 60344 R-XTR-189442 https://reactome.org/PathwayBrowser/#/R-XTR-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Xenopus tropicalis 60344 R-XTR-198824 https://reactome.org/PathwayBrowser/#/R-XTR-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Xenopus tropicalis 60344 R-XTR-198845 https://reactome.org/PathwayBrowser/#/R-XTR-198845 CYB5A:heme reduces Asc.- to AscH- IEA Xenopus tropicalis 60344 R-XTR-2168886 https://reactome.org/PathwayBrowser/#/R-XTR-2168886 Hemopexin binds Hemes IEA Xenopus tropicalis 60344 R-XTR-2995330 https://reactome.org/PathwayBrowser/#/R-XTR-2995330 COX10 transforms heme to heme O IEA Xenopus tropicalis 60344 R-XTR-382560 https://reactome.org/PathwayBrowser/#/R-XTR-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Xenopus tropicalis 60344 R-XTR-5218827 https://reactome.org/PathwayBrowser/#/R-XTR-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Xenopus tropicalis 60344 R-XTR-5218841 https://reactome.org/PathwayBrowser/#/R-XTR-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Xenopus tropicalis 60344 R-XTR-5340214 https://reactome.org/PathwayBrowser/#/R-XTR-5340214 CYGB binds O2 IEA Xenopus tropicalis 60344 R-XTR-5340226 https://reactome.org/PathwayBrowser/#/R-XTR-5340226 CYGB dioxygenates NO IEA Xenopus tropicalis 60344 R-XTR-6806831 https://reactome.org/PathwayBrowser/#/R-XTR-6806831 CYB5Rs reduce MetHb to HbA IEA Xenopus tropicalis 60344 R-XTR-71188 https://reactome.org/PathwayBrowser/#/R-XTR-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Xenopus tropicalis 60344 R-XTR-76031 https://reactome.org/PathwayBrowser/#/R-XTR-76031 2 H2O2 => O2 + 2 H2O IEA Xenopus tropicalis 60344 R-XTR-888614 https://reactome.org/PathwayBrowser/#/R-XTR-888614 IDO2 dioxygenates L-Trp to NFK IEA Xenopus tropicalis 60344 R-XTR-8981610 https://reactome.org/PathwayBrowser/#/R-XTR-8981610 Neuroglobin binds oxygen IEA Xenopus tropicalis 60344 R-XTR-8981621 https://reactome.org/PathwayBrowser/#/R-XTR-8981621 Neuroglobin:oxygen dissociates IEA Xenopus tropicalis 60344 R-XTR-8982617 https://reactome.org/PathwayBrowser/#/R-XTR-8982617 CYGB:O2 dissociates IEA Xenopus tropicalis 60344 R-XTR-9013145 https://reactome.org/PathwayBrowser/#/R-XTR-9013145 RAC1 binds effectors at the plasma membrane IEA Xenopus tropicalis 60344 R-XTR-9018808 https://reactome.org/PathwayBrowser/#/R-XTR-9018808 RAC3 binds effectors at the plasma membrane IEA Xenopus tropicalis 60344 R-XTR-917805 https://reactome.org/PathwayBrowser/#/R-XTR-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Xenopus tropicalis 60344 R-XTR-917870 https://reactome.org/PathwayBrowser/#/R-XTR-917870 SLC46A1 transports hemes from extracellular region to cytosol IEA Xenopus tropicalis 60344 R-XTR-917892 https://reactome.org/PathwayBrowser/#/R-XTR-917892 FLVCR1-1 transports heme from cytosol to extracellular region IEA Xenopus tropicalis 60344 R-XTR-917979 https://reactome.org/PathwayBrowser/#/R-XTR-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Xenopus tropicalis 60344 R-XTR-9661408 https://reactome.org/PathwayBrowser/#/R-XTR-9661408 FLVCR1-2 transports heme from mitochondrial matrix to cytosol IEA Xenopus tropicalis 60344 R-XTR-9661419 https://reactome.org/PathwayBrowser/#/R-XTR-9661419 ALB binds extracellular heme IEA Xenopus tropicalis 60344 R-XTR-9707504 https://reactome.org/PathwayBrowser/#/R-XTR-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Xenopus tropicalis 60344 R-XTR-9707523 https://reactome.org/PathwayBrowser/#/R-XTR-9707523 Hemes bind to BACH1:MAFK IEA Xenopus tropicalis 60344 R-XTR-9709317 https://reactome.org/PathwayBrowser/#/R-XTR-9709317 CO binds to free ferrohemoglobin IEA Xenopus tropicalis 60344 R-XTR-9709360 https://reactome.org/PathwayBrowser/#/R-XTR-9709360 H2O2 reduces MetHb IEA Xenopus tropicalis 60344 R-XTR-9838035 https://reactome.org/PathwayBrowser/#/R-XTR-9838035 CLPXP binds mitochondrial matrix proteins IEA Xenopus tropicalis 60344 R-XTR-9838289 https://reactome.org/PathwayBrowser/#/R-XTR-9838289 CLPXP degrades mitochondrial matrix proteins IEA Xenopus tropicalis 60366 R-BTA-8850326 https://reactome.org/PathwayBrowser/#/R-BTA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Bos taurus 60366 R-CFA-8850326 https://reactome.org/PathwayBrowser/#/R-CFA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Canis familiaris 60366 R-GGA-8850326 https://reactome.org/PathwayBrowser/#/R-GGA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Gallus gallus 60366 R-HSA-8850326 https://reactome.org/PathwayBrowser/#/R-HSA-8850326 TCR binds self-lipid-based antigen via CD1 TAS Homo sapiens 60366 R-MMU-8850326 https://reactome.org/PathwayBrowser/#/R-MMU-8850326 TCR binds self-lipid-based antigen via CD1 IEA Mus musculus 60366 R-RNO-8850326 https://reactome.org/PathwayBrowser/#/R-RNO-8850326 TCR binds self-lipid-based antigen via CD1 IEA Rattus norvegicus 60366 R-SSC-8850326 https://reactome.org/PathwayBrowser/#/R-SSC-8850326 TCR binds self-lipid-based antigen via CD1 IEA Sus scrofa 60371 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 60371 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 60371 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 60371 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 60371 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 60371 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 60371 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 60371 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 60371 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 60371 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 60371 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 60371 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 60371 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 60371 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 60371 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 60371 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 60371 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 60371 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 60377 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 60377 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 60377 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 60377 R-BTA-109903 https://reactome.org/PathwayBrowser/#/R-BTA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Bos taurus 60377 R-BTA-110137 https://reactome.org/PathwayBrowser/#/R-BTA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Bos taurus 60377 R-BTA-110138 https://reactome.org/PathwayBrowser/#/R-BTA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 60377 R-BTA-1482961 https://reactome.org/PathwayBrowser/#/R-BTA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Bos taurus 60377 R-BTA-1482962 https://reactome.org/PathwayBrowser/#/R-BTA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Bos taurus 60377 R-BTA-1482973 https://reactome.org/PathwayBrowser/#/R-BTA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Bos taurus 60377 R-BTA-1482976 https://reactome.org/PathwayBrowser/#/R-BTA-1482976 CDP-DAG is converted to PI by CDIPT IEA Bos taurus 60377 R-BTA-1483063 https://reactome.org/PathwayBrowser/#/R-BTA-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Bos taurus 60377 R-BTA-174441 https://reactome.org/PathwayBrowser/#/R-BTA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Bos taurus 60377 R-BTA-2046285 https://reactome.org/PathwayBrowser/#/R-BTA-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Bos taurus 60377 R-BTA-4084978 https://reactome.org/PathwayBrowser/#/R-BTA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Bos taurus 60377 R-BTA-4084980 https://reactome.org/PathwayBrowser/#/R-BTA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Bos taurus 60377 R-BTA-4084984 https://reactome.org/PathwayBrowser/#/R-BTA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Bos taurus 60377 R-BTA-4085033 https://reactome.org/PathwayBrowser/#/R-BTA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Bos taurus 60377 R-BTA-430028 https://reactome.org/PathwayBrowser/#/R-BTA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Bos taurus 60377 R-BTA-6788798 https://reactome.org/PathwayBrowser/#/R-BTA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 60377 R-BTA-6788810 https://reactome.org/PathwayBrowser/#/R-BTA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Bos taurus 60377 R-BTA-69144 https://reactome.org/PathwayBrowser/#/R-BTA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Bos taurus 60377 R-BTA-727807 https://reactome.org/PathwayBrowser/#/R-BTA-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Bos taurus 60377 R-BTA-73548 https://reactome.org/PathwayBrowser/#/R-BTA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Bos taurus 60377 R-BTA-73598 https://reactome.org/PathwayBrowser/#/R-BTA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Bos taurus 60377 R-BTA-73599 https://reactome.org/PathwayBrowser/#/R-BTA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Bos taurus 60377 R-BTA-75125 https://reactome.org/PathwayBrowser/#/R-BTA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Bos taurus 60377 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 60377 R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 60377 R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 60377 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 60377 R-BTA-8954327 https://reactome.org/PathwayBrowser/#/R-BTA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Bos taurus 60377 R-BTA-9603987 https://reactome.org/PathwayBrowser/#/R-BTA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Bos taurus 60377 R-BTA-9603991 https://reactome.org/PathwayBrowser/#/R-BTA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Bos taurus 60377 R-BTA-9605600 https://reactome.org/PathwayBrowser/#/R-BTA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Bos taurus 60377 R-BTA-977071 https://reactome.org/PathwayBrowser/#/R-BTA-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Bos taurus 60377 R-BTA-981497 https://reactome.org/PathwayBrowser/#/R-BTA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Bos taurus 60377 R-BTA-981809 https://reactome.org/PathwayBrowser/#/R-BTA-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Bos taurus 60377 R-BTA-981814 https://reactome.org/PathwayBrowser/#/R-BTA-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Bos taurus 60377 R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 60377 R-BTA-9845538 https://reactome.org/PathwayBrowser/#/R-BTA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Bos taurus 60377 R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 60377 R-BTA-9846305 https://reactome.org/PathwayBrowser/#/R-BTA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Bos taurus 60377 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 60377 R-CEL-109903 https://reactome.org/PathwayBrowser/#/R-CEL-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Caenorhabditis elegans 60377 R-CEL-110137 https://reactome.org/PathwayBrowser/#/R-CEL-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Caenorhabditis elegans 60377 R-CEL-110138 https://reactome.org/PathwayBrowser/#/R-CEL-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 60377 R-CEL-1482961 https://reactome.org/PathwayBrowser/#/R-CEL-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Caenorhabditis elegans 60377 R-CEL-1482962 https://reactome.org/PathwayBrowser/#/R-CEL-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Caenorhabditis elegans 60377 R-CEL-1482973 https://reactome.org/PathwayBrowser/#/R-CEL-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Caenorhabditis elegans 60377 R-CEL-1482976 https://reactome.org/PathwayBrowser/#/R-CEL-1482976 CDP-DAG is converted to PI by CDIPT IEA Caenorhabditis elegans 60377 R-CEL-1483063 https://reactome.org/PathwayBrowser/#/R-CEL-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Caenorhabditis elegans 60377 R-CEL-430028 https://reactome.org/PathwayBrowser/#/R-CEL-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Caenorhabditis elegans 60377 R-CEL-6788810 https://reactome.org/PathwayBrowser/#/R-CEL-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Caenorhabditis elegans 60377 R-CEL-727807 https://reactome.org/PathwayBrowser/#/R-CEL-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Caenorhabditis elegans 60377 R-CEL-73548 https://reactome.org/PathwayBrowser/#/R-CEL-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Caenorhabditis elegans 60377 R-CEL-73599 https://reactome.org/PathwayBrowser/#/R-CEL-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Caenorhabditis elegans 60377 R-CEL-75125 https://reactome.org/PathwayBrowser/#/R-CEL-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Caenorhabditis elegans 60377 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 60377 R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 60377 R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 60377 R-CEL-8954327 https://reactome.org/PathwayBrowser/#/R-CEL-8954327 UCKL1 phosphorylates urindine, cytidine IEA Caenorhabditis elegans 60377 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 60377 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 60377 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 60377 R-CFA-109903 https://reactome.org/PathwayBrowser/#/R-CFA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Canis familiaris 60377 R-CFA-110137 https://reactome.org/PathwayBrowser/#/R-CFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Canis familiaris 60377 R-CFA-110138 https://reactome.org/PathwayBrowser/#/R-CFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 60377 R-CFA-1482961 https://reactome.org/PathwayBrowser/#/R-CFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Canis familiaris 60377 R-CFA-1482962 https://reactome.org/PathwayBrowser/#/R-CFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Canis familiaris 60377 R-CFA-1482973 https://reactome.org/PathwayBrowser/#/R-CFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Canis familiaris 60377 R-CFA-1482976 https://reactome.org/PathwayBrowser/#/R-CFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Canis familiaris 60377 R-CFA-174441 https://reactome.org/PathwayBrowser/#/R-CFA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Canis familiaris 60377 R-CFA-2046285 https://reactome.org/PathwayBrowser/#/R-CFA-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Canis familiaris 60377 R-CFA-4084978 https://reactome.org/PathwayBrowser/#/R-CFA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Canis familiaris 60377 R-CFA-4084980 https://reactome.org/PathwayBrowser/#/R-CFA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Canis familiaris 60377 R-CFA-4084984 https://reactome.org/PathwayBrowser/#/R-CFA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Canis familiaris 60377 R-CFA-4085033 https://reactome.org/PathwayBrowser/#/R-CFA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Canis familiaris 60377 R-CFA-430028 https://reactome.org/PathwayBrowser/#/R-CFA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Canis familiaris 60377 R-CFA-6788798 https://reactome.org/PathwayBrowser/#/R-CFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 60377 R-CFA-6788810 https://reactome.org/PathwayBrowser/#/R-CFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Canis familiaris 60377 R-CFA-69144 https://reactome.org/PathwayBrowser/#/R-CFA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Canis familiaris 60377 R-CFA-727807 https://reactome.org/PathwayBrowser/#/R-CFA-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Canis familiaris 60377 R-CFA-73548 https://reactome.org/PathwayBrowser/#/R-CFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Canis familiaris 60377 R-CFA-73598 https://reactome.org/PathwayBrowser/#/R-CFA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Canis familiaris 60377 R-CFA-73599 https://reactome.org/PathwayBrowser/#/R-CFA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Canis familiaris 60377 R-CFA-75125 https://reactome.org/PathwayBrowser/#/R-CFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Canis familiaris 60377 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 60377 R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 60377 R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 60377 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 60377 R-CFA-8954327 https://reactome.org/PathwayBrowser/#/R-CFA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Canis familiaris 60377 R-CFA-9603987 https://reactome.org/PathwayBrowser/#/R-CFA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Canis familiaris 60377 R-CFA-9603991 https://reactome.org/PathwayBrowser/#/R-CFA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Canis familiaris 60377 R-CFA-9605600 https://reactome.org/PathwayBrowser/#/R-CFA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Canis familiaris 60377 R-CFA-977071 https://reactome.org/PathwayBrowser/#/R-CFA-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Canis familiaris 60377 R-CFA-981497 https://reactome.org/PathwayBrowser/#/R-CFA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Canis familiaris 60377 R-CFA-981809 https://reactome.org/PathwayBrowser/#/R-CFA-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Canis familiaris 60377 R-CFA-981814 https://reactome.org/PathwayBrowser/#/R-CFA-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Canis familiaris 60377 R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 60377 R-CFA-9845538 https://reactome.org/PathwayBrowser/#/R-CFA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Canis familiaris 60377 R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 60377 R-CFA-9846305 https://reactome.org/PathwayBrowser/#/R-CFA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Canis familiaris 60377 R-CGR-2033005 https://reactome.org/PathwayBrowser/#/R-CGR-2033005 Sialylation of Pre-Notch TAS Cricetulus griseus 60377 R-DDI-109903 https://reactome.org/PathwayBrowser/#/R-DDI-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Dictyostelium discoideum 60377 R-DDI-1482961 https://reactome.org/PathwayBrowser/#/R-DDI-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Dictyostelium discoideum 60377 R-DDI-1482962 https://reactome.org/PathwayBrowser/#/R-DDI-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Dictyostelium discoideum 60377 R-DDI-1482973 https://reactome.org/PathwayBrowser/#/R-DDI-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Dictyostelium discoideum 60377 R-DDI-1482976 https://reactome.org/PathwayBrowser/#/R-DDI-1482976 CDP-DAG is converted to PI by CDIPT IEA Dictyostelium discoideum 60377 R-DDI-430028 https://reactome.org/PathwayBrowser/#/R-DDI-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Dictyostelium discoideum 60377 R-DDI-6788798 https://reactome.org/PathwayBrowser/#/R-DDI-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 60377 R-DDI-6788810 https://reactome.org/PathwayBrowser/#/R-DDI-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Dictyostelium discoideum 60377 R-DDI-73548 https://reactome.org/PathwayBrowser/#/R-DDI-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Dictyostelium discoideum 60377 R-DDI-73599 https://reactome.org/PathwayBrowser/#/R-DDI-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Dictyostelium discoideum 60377 R-DDI-75125 https://reactome.org/PathwayBrowser/#/R-DDI-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Dictyostelium discoideum 60377 R-DDI-8954327 https://reactome.org/PathwayBrowser/#/R-DDI-8954327 UCKL1 phosphorylates urindine, cytidine IEA Dictyostelium discoideum 60377 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 60377 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 60377 R-DME-109903 https://reactome.org/PathwayBrowser/#/R-DME-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Drosophila melanogaster 60377 R-DME-110137 https://reactome.org/PathwayBrowser/#/R-DME-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Drosophila melanogaster 60377 R-DME-110138 https://reactome.org/PathwayBrowser/#/R-DME-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 60377 R-DME-1482961 https://reactome.org/PathwayBrowser/#/R-DME-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Drosophila melanogaster 60377 R-DME-1482962 https://reactome.org/PathwayBrowser/#/R-DME-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Drosophila melanogaster 60377 R-DME-1482973 https://reactome.org/PathwayBrowser/#/R-DME-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Drosophila melanogaster 60377 R-DME-1482976 https://reactome.org/PathwayBrowser/#/R-DME-1482976 CDP-DAG is converted to PI by CDIPT IEA Drosophila melanogaster 60377 R-DME-1483063 https://reactome.org/PathwayBrowser/#/R-DME-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Drosophila melanogaster 60377 R-DME-4085033 https://reactome.org/PathwayBrowser/#/R-DME-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Drosophila melanogaster 60377 R-DME-430028 https://reactome.org/PathwayBrowser/#/R-DME-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Drosophila melanogaster 60377 R-DME-6788798 https://reactome.org/PathwayBrowser/#/R-DME-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 60377 R-DME-6788810 https://reactome.org/PathwayBrowser/#/R-DME-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Drosophila melanogaster 60377 R-DME-69144 https://reactome.org/PathwayBrowser/#/R-DME-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Drosophila melanogaster 60377 R-DME-73548 https://reactome.org/PathwayBrowser/#/R-DME-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Drosophila melanogaster 60377 R-DME-73599 https://reactome.org/PathwayBrowser/#/R-DME-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Drosophila melanogaster 60377 R-DME-75125 https://reactome.org/PathwayBrowser/#/R-DME-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Drosophila melanogaster 60377 R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 60377 R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 60377 R-DME-8954327 https://reactome.org/PathwayBrowser/#/R-DME-8954327 UCKL1 phosphorylates urindine, cytidine IEA Drosophila melanogaster 60377 R-DME-977071 https://reactome.org/PathwayBrowser/#/R-DME-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Drosophila melanogaster 60377 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 60377 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 60377 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 60377 R-DRE-109903 https://reactome.org/PathwayBrowser/#/R-DRE-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Danio rerio 60377 R-DRE-110137 https://reactome.org/PathwayBrowser/#/R-DRE-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Danio rerio 60377 R-DRE-110138 https://reactome.org/PathwayBrowser/#/R-DRE-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 60377 R-DRE-1482961 https://reactome.org/PathwayBrowser/#/R-DRE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Danio rerio 60377 R-DRE-1482962 https://reactome.org/PathwayBrowser/#/R-DRE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Danio rerio 60377 R-DRE-1482973 https://reactome.org/PathwayBrowser/#/R-DRE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Danio rerio 60377 R-DRE-1482976 https://reactome.org/PathwayBrowser/#/R-DRE-1482976 CDP-DAG is converted to PI by CDIPT IEA Danio rerio 60377 R-DRE-1483063 https://reactome.org/PathwayBrowser/#/R-DRE-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Danio rerio 60377 R-DRE-2046285 https://reactome.org/PathwayBrowser/#/R-DRE-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Danio rerio 60377 R-DRE-4084978 https://reactome.org/PathwayBrowser/#/R-DRE-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Danio rerio 60377 R-DRE-4084980 https://reactome.org/PathwayBrowser/#/R-DRE-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Danio rerio 60377 R-DRE-4084984 https://reactome.org/PathwayBrowser/#/R-DRE-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Danio rerio 60377 R-DRE-4085033 https://reactome.org/PathwayBrowser/#/R-DRE-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Danio rerio 60377 R-DRE-6788798 https://reactome.org/PathwayBrowser/#/R-DRE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 60377 R-DRE-6788810 https://reactome.org/PathwayBrowser/#/R-DRE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Danio rerio 60377 R-DRE-727807 https://reactome.org/PathwayBrowser/#/R-DRE-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Danio rerio 60377 R-DRE-73548 https://reactome.org/PathwayBrowser/#/R-DRE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Danio rerio 60377 R-DRE-73598 https://reactome.org/PathwayBrowser/#/R-DRE-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Danio rerio 60377 R-DRE-73599 https://reactome.org/PathwayBrowser/#/R-DRE-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Danio rerio 60377 R-DRE-75125 https://reactome.org/PathwayBrowser/#/R-DRE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Danio rerio 60377 R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 60377 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 60377 R-DRE-9605600 https://reactome.org/PathwayBrowser/#/R-DRE-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Danio rerio 60377 R-DRE-981497 https://reactome.org/PathwayBrowser/#/R-DRE-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Danio rerio 60377 R-DRE-981809 https://reactome.org/PathwayBrowser/#/R-DRE-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Danio rerio 60377 R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 60377 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 60377 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 60377 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 60377 R-GGA-109903 https://reactome.org/PathwayBrowser/#/R-GGA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Gallus gallus 60377 R-GGA-110137 https://reactome.org/PathwayBrowser/#/R-GGA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Gallus gallus 60377 R-GGA-110138 https://reactome.org/PathwayBrowser/#/R-GGA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 60377 R-GGA-1482961 https://reactome.org/PathwayBrowser/#/R-GGA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Gallus gallus 60377 R-GGA-1482962 https://reactome.org/PathwayBrowser/#/R-GGA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Gallus gallus 60377 R-GGA-1482973 https://reactome.org/PathwayBrowser/#/R-GGA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Gallus gallus 60377 R-GGA-1483063 https://reactome.org/PathwayBrowser/#/R-GGA-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Gallus gallus 60377 R-GGA-2046285 https://reactome.org/PathwayBrowser/#/R-GGA-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Gallus gallus 60377 R-GGA-4084978 https://reactome.org/PathwayBrowser/#/R-GGA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Gallus gallus 60377 R-GGA-4084980 https://reactome.org/PathwayBrowser/#/R-GGA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Gallus gallus 60377 R-GGA-4084984 https://reactome.org/PathwayBrowser/#/R-GGA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Gallus gallus 60377 R-GGA-4085033 https://reactome.org/PathwayBrowser/#/R-GGA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Gallus gallus 60377 R-GGA-430028 https://reactome.org/PathwayBrowser/#/R-GGA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Gallus gallus 60377 R-GGA-6788798 https://reactome.org/PathwayBrowser/#/R-GGA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 60377 R-GGA-6788810 https://reactome.org/PathwayBrowser/#/R-GGA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus 60377 R-GGA-727807 https://reactome.org/PathwayBrowser/#/R-GGA-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Gallus gallus 60377 R-GGA-73548 https://reactome.org/PathwayBrowser/#/R-GGA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Gallus gallus 60377 R-GGA-73598 https://reactome.org/PathwayBrowser/#/R-GGA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Gallus gallus 60377 R-GGA-73599 https://reactome.org/PathwayBrowser/#/R-GGA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Gallus gallus 60377 R-GGA-75125 https://reactome.org/PathwayBrowser/#/R-GGA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Gallus gallus 60377 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 60377 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 60377 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 60377 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 60377 R-GGA-8954327 https://reactome.org/PathwayBrowser/#/R-GGA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Gallus gallus 60377 R-GGA-9603987 https://reactome.org/PathwayBrowser/#/R-GGA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Gallus gallus 60377 R-GGA-9603991 https://reactome.org/PathwayBrowser/#/R-GGA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Gallus gallus 60377 R-GGA-9605600 https://reactome.org/PathwayBrowser/#/R-GGA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Gallus gallus 60377 R-GGA-977071 https://reactome.org/PathwayBrowser/#/R-GGA-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Gallus gallus 60377 R-GGA-981497 https://reactome.org/PathwayBrowser/#/R-GGA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Gallus gallus 60377 R-GGA-981809 https://reactome.org/PathwayBrowser/#/R-GGA-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Gallus gallus 60377 R-GGA-981814 https://reactome.org/PathwayBrowser/#/R-GGA-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Gallus gallus 60377 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 60377 R-GGA-9845538 https://reactome.org/PathwayBrowser/#/R-GGA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Gallus gallus 60377 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 60377 R-GGA-9846305 https://reactome.org/PathwayBrowser/#/R-GGA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Gallus gallus 60377 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 60377 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 60377 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 60377 R-HSA-109903 https://reactome.org/PathwayBrowser/#/R-HSA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] TAS Homo sapiens 60377 R-HSA-110137 https://reactome.org/PathwayBrowser/#/R-HSA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP TAS Homo sapiens 60377 R-HSA-110138 https://reactome.org/PathwayBrowser/#/R-HSA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 60377 R-HSA-1482939 https://reactome.org/PathwayBrowser/#/R-HSA-1482939 CDP-DAG is converted to PGP by PGS1 IEA Homo sapiens 60377 R-HSA-1482961 https://reactome.org/PathwayBrowser/#/R-HSA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane TAS Homo sapiens 60377 R-HSA-1482962 https://reactome.org/PathwayBrowser/#/R-HSA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 TAS Homo sapiens 60377 R-HSA-1482973 https://reactome.org/PathwayBrowser/#/R-HSA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane TAS Homo sapiens 60377 R-HSA-1482976 https://reactome.org/PathwayBrowser/#/R-HSA-1482976 CDP-DAG is converted to PI by CDIPT TAS Homo sapiens 60377 R-HSA-1483063 https://reactome.org/PathwayBrowser/#/R-HSA-1483063 PG and CDP-DAG are converted to CL by CRLS1 TAS Homo sapiens 60377 R-HSA-174441 https://reactome.org/PathwayBrowser/#/R-HSA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand TAS Homo sapiens 60377 R-HSA-1912378 https://reactome.org/PathwayBrowser/#/R-HSA-1912378 Sialylation of Pre-NOTCH IEA Homo sapiens 60377 R-HSA-2046285 https://reactome.org/PathwayBrowser/#/R-HSA-2046285 The keratan chain can be capped by N-acetylneuraminic acid TAS Homo sapiens 60377 R-HSA-4084978 https://reactome.org/PathwayBrowser/#/R-HSA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues TAS Homo sapiens 60377 R-HSA-4084980 https://reactome.org/PathwayBrowser/#/R-HSA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) TAS Homo sapiens 60377 R-HSA-4084984 https://reactome.org/PathwayBrowser/#/R-HSA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) TAS Homo sapiens 60377 R-HSA-4085033 https://reactome.org/PathwayBrowser/#/R-HSA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) TAS Homo sapiens 60377 R-HSA-429845 https://reactome.org/PathwayBrowser/#/R-HSA-429845 5' to 3' exoribonuclease hydrolyzes decapped mRNA IEA Homo sapiens 60377 R-HSA-430028 https://reactome.org/PathwayBrowser/#/R-HSA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion TAS Homo sapiens 60377 R-HSA-5651942 https://reactome.org/PathwayBrowser/#/R-HSA-5651942 Defective SLC35A1 does not exchange CMP-Neu5Ac for CMP TAS Homo sapiens 60377 R-HSA-6788798 https://reactome.org/PathwayBrowser/#/R-HSA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 60377 R-HSA-6788810 https://reactome.org/PathwayBrowser/#/R-HSA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs TAS Homo sapiens 60377 R-HSA-69144 https://reactome.org/PathwayBrowser/#/R-HSA-69144 Removal of RNA primer and dissociation of RPA and Dna2 TAS Homo sapiens 60377 R-HSA-727807 https://reactome.org/PathwayBrowser/#/R-HSA-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP TAS Homo sapiens 60377 R-HSA-73548 https://reactome.org/PathwayBrowser/#/R-HSA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) TAS Homo sapiens 60377 R-HSA-73598 https://reactome.org/PathwayBrowser/#/R-HSA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) TAS Homo sapiens 60377 R-HSA-73599 https://reactome.org/PathwayBrowser/#/R-HSA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] TAS Homo sapiens 60377 R-HSA-75125 https://reactome.org/PathwayBrowser/#/R-HSA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) TAS Homo sapiens 60377 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 60377 R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 60377 R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 60377 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 60377 R-HSA-8954327 https://reactome.org/PathwayBrowser/#/R-HSA-8954327 UCKL1 phosphorylates urindine, cytidine TAS Homo sapiens 60377 R-HSA-9603987 https://reactome.org/PathwayBrowser/#/R-HSA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG TAS Homo sapiens 60377 R-HSA-9603991 https://reactome.org/PathwayBrowser/#/R-HSA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG TAS Homo sapiens 60377 R-HSA-9605600 https://reactome.org/PathwayBrowser/#/R-HSA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG TAS Homo sapiens 60377 R-HSA-977071 https://reactome.org/PathwayBrowser/#/R-HSA-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens TAS Homo sapiens 60377 R-HSA-981497 https://reactome.org/PathwayBrowser/#/R-HSA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position TAS Homo sapiens 60377 R-HSA-981809 https://reactome.org/PathwayBrowser/#/R-HSA-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen TAS Homo sapiens 60377 R-HSA-981814 https://reactome.org/PathwayBrowser/#/R-HSA-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins TAS Homo sapiens 60377 R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 60377 R-HSA-9845538 https://reactome.org/PathwayBrowser/#/R-HSA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides TAS Homo sapiens 60377 R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 60377 R-HSA-9846305 https://reactome.org/PathwayBrowser/#/R-HSA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b TAS Homo sapiens 60377 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 60377 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 60377 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 60377 R-MMU-109903 https://reactome.org/PathwayBrowser/#/R-MMU-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Mus musculus 60377 R-MMU-110137 https://reactome.org/PathwayBrowser/#/R-MMU-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Mus musculus 60377 R-MMU-110138 https://reactome.org/PathwayBrowser/#/R-MMU-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 60377 R-MMU-1482961 https://reactome.org/PathwayBrowser/#/R-MMU-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Mus musculus 60377 R-MMU-1482962 https://reactome.org/PathwayBrowser/#/R-MMU-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Mus musculus 60377 R-MMU-1482973 https://reactome.org/PathwayBrowser/#/R-MMU-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Mus musculus 60377 R-MMU-1482976 https://reactome.org/PathwayBrowser/#/R-MMU-1482976 CDP-DAG is converted to PI by CDIPT IEA Mus musculus 60377 R-MMU-1483063 https://reactome.org/PathwayBrowser/#/R-MMU-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Mus musculus 60377 R-MMU-174441 https://reactome.org/PathwayBrowser/#/R-MMU-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Mus musculus 60377 R-MMU-2046285 https://reactome.org/PathwayBrowser/#/R-MMU-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Mus musculus 60377 R-MMU-4084978 https://reactome.org/PathwayBrowser/#/R-MMU-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Mus musculus 60377 R-MMU-4084980 https://reactome.org/PathwayBrowser/#/R-MMU-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Mus musculus 60377 R-MMU-4084984 https://reactome.org/PathwayBrowser/#/R-MMU-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Mus musculus 60377 R-MMU-4085033 https://reactome.org/PathwayBrowser/#/R-MMU-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Mus musculus 60377 R-MMU-430028 https://reactome.org/PathwayBrowser/#/R-MMU-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Mus musculus 60377 R-MMU-6788798 https://reactome.org/PathwayBrowser/#/R-MMU-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 60377 R-MMU-6788810 https://reactome.org/PathwayBrowser/#/R-MMU-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Mus musculus 60377 R-MMU-69144 https://reactome.org/PathwayBrowser/#/R-MMU-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Mus musculus 60377 R-MMU-727807 https://reactome.org/PathwayBrowser/#/R-MMU-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Mus musculus 60377 R-MMU-73548 https://reactome.org/PathwayBrowser/#/R-MMU-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Mus musculus 60377 R-MMU-73598 https://reactome.org/PathwayBrowser/#/R-MMU-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Mus musculus 60377 R-MMU-73599 https://reactome.org/PathwayBrowser/#/R-MMU-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Mus musculus 60377 R-MMU-75125 https://reactome.org/PathwayBrowser/#/R-MMU-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Mus musculus 60377 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 60377 R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 60377 R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 60377 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 60377 R-MMU-8954327 https://reactome.org/PathwayBrowser/#/R-MMU-8954327 UCKL1 phosphorylates urindine, cytidine IEA Mus musculus 60377 R-MMU-9603987 https://reactome.org/PathwayBrowser/#/R-MMU-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Mus musculus 60377 R-MMU-9603991 https://reactome.org/PathwayBrowser/#/R-MMU-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Mus musculus 60377 R-MMU-9605600 https://reactome.org/PathwayBrowser/#/R-MMU-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Mus musculus 60377 R-MMU-977071 https://reactome.org/PathwayBrowser/#/R-MMU-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Mus musculus 60377 R-MMU-981497 https://reactome.org/PathwayBrowser/#/R-MMU-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Mus musculus 60377 R-MMU-981809 https://reactome.org/PathwayBrowser/#/R-MMU-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Mus musculus 60377 R-MMU-981814 https://reactome.org/PathwayBrowser/#/R-MMU-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Mus musculus 60377 R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 60377 R-MMU-9845538 https://reactome.org/PathwayBrowser/#/R-MMU-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Mus musculus 60377 R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 60377 R-MMU-9846305 https://reactome.org/PathwayBrowser/#/R-MMU-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Mus musculus 60377 R-PFA-110137 https://reactome.org/PathwayBrowser/#/R-PFA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Plasmodium falciparum 60377 R-PFA-110138 https://reactome.org/PathwayBrowser/#/R-PFA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 60377 R-PFA-1482961 https://reactome.org/PathwayBrowser/#/R-PFA-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Plasmodium falciparum 60377 R-PFA-1482962 https://reactome.org/PathwayBrowser/#/R-PFA-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Plasmodium falciparum 60377 R-PFA-1482973 https://reactome.org/PathwayBrowser/#/R-PFA-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Plasmodium falciparum 60377 R-PFA-1482976 https://reactome.org/PathwayBrowser/#/R-PFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Plasmodium falciparum 60377 R-PFA-6788798 https://reactome.org/PathwayBrowser/#/R-PFA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 60377 R-PFA-6788810 https://reactome.org/PathwayBrowser/#/R-PFA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Plasmodium falciparum 60377 R-PFA-727807 https://reactome.org/PathwayBrowser/#/R-PFA-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Plasmodium falciparum 60377 R-PFA-73548 https://reactome.org/PathwayBrowser/#/R-PFA-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Plasmodium falciparum 60377 R-PFA-75125 https://reactome.org/PathwayBrowser/#/R-PFA-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Plasmodium falciparum 60377 R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 60377 R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 60377 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 60377 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 60377 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 60377 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 60377 R-RNO-109903 https://reactome.org/PathwayBrowser/#/R-RNO-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Rattus norvegicus 60377 R-RNO-110137 https://reactome.org/PathwayBrowser/#/R-RNO-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Rattus norvegicus 60377 R-RNO-110138 https://reactome.org/PathwayBrowser/#/R-RNO-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 60377 R-RNO-1482961 https://reactome.org/PathwayBrowser/#/R-RNO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Rattus norvegicus 60377 R-RNO-1482962 https://reactome.org/PathwayBrowser/#/R-RNO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Rattus norvegicus 60377 R-RNO-1482973 https://reactome.org/PathwayBrowser/#/R-RNO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Rattus norvegicus 60377 R-RNO-1482976 https://reactome.org/PathwayBrowser/#/R-RNO-1482976 CDP-DAG is converted to PI by CDIPT IEA Rattus norvegicus 60377 R-RNO-1482978 https://reactome.org/PathwayBrowser/#/R-RNO-1482978 CDP-DAG is converted to PGP by Pgs1 TAS Rattus norvegicus 60377 R-RNO-1483063 https://reactome.org/PathwayBrowser/#/R-RNO-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Rattus norvegicus 60377 R-RNO-174441 https://reactome.org/PathwayBrowser/#/R-RNO-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Rattus norvegicus 60377 R-RNO-2046285 https://reactome.org/PathwayBrowser/#/R-RNO-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Rattus norvegicus 60377 R-RNO-4084978 https://reactome.org/PathwayBrowser/#/R-RNO-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Rattus norvegicus 60377 R-RNO-4084980 https://reactome.org/PathwayBrowser/#/R-RNO-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Rattus norvegicus 60377 R-RNO-4084984 https://reactome.org/PathwayBrowser/#/R-RNO-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Rattus norvegicus 60377 R-RNO-4085033 https://reactome.org/PathwayBrowser/#/R-RNO-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Rattus norvegicus 60377 R-RNO-430028 https://reactome.org/PathwayBrowser/#/R-RNO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Rattus norvegicus 60377 R-RNO-6788798 https://reactome.org/PathwayBrowser/#/R-RNO-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 60377 R-RNO-6788810 https://reactome.org/PathwayBrowser/#/R-RNO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus 60377 R-RNO-69144 https://reactome.org/PathwayBrowser/#/R-RNO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Rattus norvegicus 60377 R-RNO-727807 https://reactome.org/PathwayBrowser/#/R-RNO-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Rattus norvegicus 60377 R-RNO-73548 https://reactome.org/PathwayBrowser/#/R-RNO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Rattus norvegicus 60377 R-RNO-73598 https://reactome.org/PathwayBrowser/#/R-RNO-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Rattus norvegicus 60377 R-RNO-73599 https://reactome.org/PathwayBrowser/#/R-RNO-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Rattus norvegicus 60377 R-RNO-75125 https://reactome.org/PathwayBrowser/#/R-RNO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Rattus norvegicus 60377 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 60377 R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 60377 R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 60377 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 60377 R-RNO-8954327 https://reactome.org/PathwayBrowser/#/R-RNO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Rattus norvegicus 60377 R-RNO-9603987 https://reactome.org/PathwayBrowser/#/R-RNO-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Rattus norvegicus 60377 R-RNO-9603991 https://reactome.org/PathwayBrowser/#/R-RNO-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Rattus norvegicus 60377 R-RNO-9605600 https://reactome.org/PathwayBrowser/#/R-RNO-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Rattus norvegicus 60377 R-RNO-977071 https://reactome.org/PathwayBrowser/#/R-RNO-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Rattus norvegicus 60377 R-RNO-981497 https://reactome.org/PathwayBrowser/#/R-RNO-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Rattus norvegicus 60377 R-RNO-981809 https://reactome.org/PathwayBrowser/#/R-RNO-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Rattus norvegicus 60377 R-RNO-981814 https://reactome.org/PathwayBrowser/#/R-RNO-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Rattus norvegicus 60377 R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 60377 R-RNO-9845538 https://reactome.org/PathwayBrowser/#/R-RNO-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Rattus norvegicus 60377 R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 60377 R-RNO-9846305 https://reactome.org/PathwayBrowser/#/R-RNO-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Rattus norvegicus 60377 R-SCE-1482961 https://reactome.org/PathwayBrowser/#/R-SCE-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Saccharomyces cerevisiae 60377 R-SCE-1482962 https://reactome.org/PathwayBrowser/#/R-SCE-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Saccharomyces cerevisiae 60377 R-SCE-1482973 https://reactome.org/PathwayBrowser/#/R-SCE-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Saccharomyces cerevisiae 60377 R-SCE-1482976 https://reactome.org/PathwayBrowser/#/R-SCE-1482976 CDP-DAG is converted to PI by CDIPT IEA Saccharomyces cerevisiae 60377 R-SCE-1483063 https://reactome.org/PathwayBrowser/#/R-SCE-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Saccharomyces cerevisiae 60377 R-SCE-429913 https://reactome.org/PathwayBrowser/#/R-SCE-429913 5' to 3' Exoribonuclease Digestion of Decapped mRNA (yeast) TAS Saccharomyces cerevisiae 60377 R-SCE-430028 https://reactome.org/PathwayBrowser/#/R-SCE-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Saccharomyces cerevisiae 60377 R-SCE-6788798 https://reactome.org/PathwayBrowser/#/R-SCE-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 60377 R-SCE-6788810 https://reactome.org/PathwayBrowser/#/R-SCE-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Saccharomyces cerevisiae 60377 R-SCE-73548 https://reactome.org/PathwayBrowser/#/R-SCE-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Saccharomyces cerevisiae 60377 R-SCE-75125 https://reactome.org/PathwayBrowser/#/R-SCE-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Saccharomyces cerevisiae 60377 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 60377 R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 60377 R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 60377 R-SCE-8954327 https://reactome.org/PathwayBrowser/#/R-SCE-8954327 UCKL1 phosphorylates urindine, cytidine IEA Saccharomyces cerevisiae 60377 R-SPO-1482961 https://reactome.org/PathwayBrowser/#/R-SPO-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Schizosaccharomyces pombe 60377 R-SPO-1482962 https://reactome.org/PathwayBrowser/#/R-SPO-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Schizosaccharomyces pombe 60377 R-SPO-1482973 https://reactome.org/PathwayBrowser/#/R-SPO-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Schizosaccharomyces pombe 60377 R-SPO-1482976 https://reactome.org/PathwayBrowser/#/R-SPO-1482976 CDP-DAG is converted to PI by CDIPT IEA Schizosaccharomyces pombe 60377 R-SPO-1483063 https://reactome.org/PathwayBrowser/#/R-SPO-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Schizosaccharomyces pombe 60377 R-SPO-430028 https://reactome.org/PathwayBrowser/#/R-SPO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Schizosaccharomyces pombe 60377 R-SPO-6788810 https://reactome.org/PathwayBrowser/#/R-SPO-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Schizosaccharomyces pombe 60377 R-SPO-69144 https://reactome.org/PathwayBrowser/#/R-SPO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Schizosaccharomyces pombe 60377 R-SPO-73548 https://reactome.org/PathwayBrowser/#/R-SPO-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Schizosaccharomyces pombe 60377 R-SPO-75125 https://reactome.org/PathwayBrowser/#/R-SPO-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Schizosaccharomyces pombe 60377 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 60377 R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 60377 R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 60377 R-SPO-8954327 https://reactome.org/PathwayBrowser/#/R-SPO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Schizosaccharomyces pombe 60377 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 60377 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 60377 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 60377 R-SSC-109903 https://reactome.org/PathwayBrowser/#/R-SSC-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Sus scrofa 60377 R-SSC-110137 https://reactome.org/PathwayBrowser/#/R-SSC-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Sus scrofa 60377 R-SSC-110138 https://reactome.org/PathwayBrowser/#/R-SSC-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 60377 R-SSC-1482961 https://reactome.org/PathwayBrowser/#/R-SSC-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Sus scrofa 60377 R-SSC-1482962 https://reactome.org/PathwayBrowser/#/R-SSC-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Sus scrofa 60377 R-SSC-1482973 https://reactome.org/PathwayBrowser/#/R-SSC-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Sus scrofa 60377 R-SSC-1482976 https://reactome.org/PathwayBrowser/#/R-SSC-1482976 CDP-DAG is converted to PI by CDIPT IEA Sus scrofa 60377 R-SSC-1483063 https://reactome.org/PathwayBrowser/#/R-SSC-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Sus scrofa 60377 R-SSC-174441 https://reactome.org/PathwayBrowser/#/R-SSC-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Sus scrofa 60377 R-SSC-2046285 https://reactome.org/PathwayBrowser/#/R-SSC-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Sus scrofa 60377 R-SSC-4084978 https://reactome.org/PathwayBrowser/#/R-SSC-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Sus scrofa 60377 R-SSC-4084980 https://reactome.org/PathwayBrowser/#/R-SSC-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Sus scrofa 60377 R-SSC-4084984 https://reactome.org/PathwayBrowser/#/R-SSC-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Sus scrofa 60377 R-SSC-4085033 https://reactome.org/PathwayBrowser/#/R-SSC-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Sus scrofa 60377 R-SSC-430028 https://reactome.org/PathwayBrowser/#/R-SSC-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Sus scrofa 60377 R-SSC-6788798 https://reactome.org/PathwayBrowser/#/R-SSC-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 60377 R-SSC-6788810 https://reactome.org/PathwayBrowser/#/R-SSC-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa 60377 R-SSC-69144 https://reactome.org/PathwayBrowser/#/R-SSC-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Sus scrofa 60377 R-SSC-727807 https://reactome.org/PathwayBrowser/#/R-SSC-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Sus scrofa 60377 R-SSC-73548 https://reactome.org/PathwayBrowser/#/R-SSC-73548 (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) IEA Sus scrofa 60377 R-SSC-73599 https://reactome.org/PathwayBrowser/#/R-SSC-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Sus scrofa 60377 R-SSC-75125 https://reactome.org/PathwayBrowser/#/R-SSC-75125 (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) IEA Sus scrofa 60377 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 60377 R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 60377 R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 60377 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 60377 R-SSC-8954327 https://reactome.org/PathwayBrowser/#/R-SSC-8954327 UCKL1 phosphorylates urindine, cytidine IEA Sus scrofa 60377 R-SSC-9603987 https://reactome.org/PathwayBrowser/#/R-SSC-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Sus scrofa 60377 R-SSC-9603991 https://reactome.org/PathwayBrowser/#/R-SSC-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Sus scrofa 60377 R-SSC-9605600 https://reactome.org/PathwayBrowser/#/R-SSC-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Sus scrofa 60377 R-SSC-977071 https://reactome.org/PathwayBrowser/#/R-SSC-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Sus scrofa 60377 R-SSC-981497 https://reactome.org/PathwayBrowser/#/R-SSC-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Sus scrofa 60377 R-SSC-981809 https://reactome.org/PathwayBrowser/#/R-SSC-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Sus scrofa 60377 R-SSC-981814 https://reactome.org/PathwayBrowser/#/R-SSC-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Sus scrofa 60377 R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 60377 R-SSC-9845538 https://reactome.org/PathwayBrowser/#/R-SSC-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Sus scrofa 60377 R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 60377 R-SSC-9846305 https://reactome.org/PathwayBrowser/#/R-SSC-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Sus scrofa 60377 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 60377 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 60377 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 60377 R-XTR-109903 https://reactome.org/PathwayBrowser/#/R-XTR-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Xenopus tropicalis 60377 R-XTR-110137 https://reactome.org/PathwayBrowser/#/R-XTR-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Xenopus tropicalis 60377 R-XTR-110138 https://reactome.org/PathwayBrowser/#/R-XTR-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 60377 R-XTR-1482961 https://reactome.org/PathwayBrowser/#/R-XTR-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Xenopus tropicalis 60377 R-XTR-1482962 https://reactome.org/PathwayBrowser/#/R-XTR-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Xenopus tropicalis 60377 R-XTR-1482973 https://reactome.org/PathwayBrowser/#/R-XTR-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Xenopus tropicalis 60377 R-XTR-1482976 https://reactome.org/PathwayBrowser/#/R-XTR-1482976 CDP-DAG is converted to PI by CDIPT IEA Xenopus tropicalis 60377 R-XTR-2046285 https://reactome.org/PathwayBrowser/#/R-XTR-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Xenopus tropicalis 60377 R-XTR-4084978 https://reactome.org/PathwayBrowser/#/R-XTR-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Xenopus tropicalis 60377 R-XTR-4084980 https://reactome.org/PathwayBrowser/#/R-XTR-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Xenopus tropicalis 60377 R-XTR-4084984 https://reactome.org/PathwayBrowser/#/R-XTR-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Xenopus tropicalis 60377 R-XTR-4085033 https://reactome.org/PathwayBrowser/#/R-XTR-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Xenopus tropicalis 60377 R-XTR-430028 https://reactome.org/PathwayBrowser/#/R-XTR-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Xenopus tropicalis 60377 R-XTR-6788798 https://reactome.org/PathwayBrowser/#/R-XTR-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 60377 R-XTR-6788810 https://reactome.org/PathwayBrowser/#/R-XTR-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Xenopus tropicalis 60377 R-XTR-727807 https://reactome.org/PathwayBrowser/#/R-XTR-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Xenopus tropicalis 60377 R-XTR-73598 https://reactome.org/PathwayBrowser/#/R-XTR-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Xenopus tropicalis 60377 R-XTR-73599 https://reactome.org/PathwayBrowser/#/R-XTR-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Xenopus tropicalis 60377 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 60377 R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 60377 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 60377 R-XTR-8954327 https://reactome.org/PathwayBrowser/#/R-XTR-8954327 UCKL1 phosphorylates urindine, cytidine IEA Xenopus tropicalis 60377 R-XTR-9603987 https://reactome.org/PathwayBrowser/#/R-XTR-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Xenopus tropicalis 60377 R-XTR-9603991 https://reactome.org/PathwayBrowser/#/R-XTR-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Xenopus tropicalis 60377 R-XTR-9605600 https://reactome.org/PathwayBrowser/#/R-XTR-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Xenopus tropicalis 60377 R-XTR-977071 https://reactome.org/PathwayBrowser/#/R-XTR-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Xenopus tropicalis 60377 R-XTR-981497 https://reactome.org/PathwayBrowser/#/R-XTR-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Xenopus tropicalis 60377 R-XTR-981809 https://reactome.org/PathwayBrowser/#/R-XTR-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Xenopus tropicalis 60377 R-XTR-9845538 https://reactome.org/PathwayBrowser/#/R-XTR-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Xenopus tropicalis 60377 R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 60377 R-XTR-9846305 https://reactome.org/PathwayBrowser/#/R-XTR-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Xenopus tropicalis 60430 R-BTA-1482759 https://reactome.org/PathwayBrowser/#/R-BTA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Bos taurus 60430 R-BTA-1482775 https://reactome.org/PathwayBrowser/#/R-BTA-1482775 MLCL is acylated to CL by HADH (IM) IEA Bos taurus 60430 R-BTA-1482781 https://reactome.org/PathwayBrowser/#/R-BTA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Bos taurus 60430 R-BTA-1482794 https://reactome.org/PathwayBrowser/#/R-BTA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Bos taurus 60430 R-BTA-1482850 https://reactome.org/PathwayBrowser/#/R-BTA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Bos taurus 60430 R-BTA-1482861 https://reactome.org/PathwayBrowser/#/R-BTA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Bos taurus 60430 R-BTA-1482867 https://reactome.org/PathwayBrowser/#/R-BTA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Bos taurus 60430 R-BTA-1482894 https://reactome.org/PathwayBrowser/#/R-BTA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Bos taurus 60430 R-CEL-1482775 https://reactome.org/PathwayBrowser/#/R-CEL-1482775 MLCL is acylated to CL by HADH (IM) IEA Caenorhabditis elegans 60430 R-CEL-1482781 https://reactome.org/PathwayBrowser/#/R-CEL-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 60430 R-CEL-1482794 https://reactome.org/PathwayBrowser/#/R-CEL-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 60430 R-CEL-1482850 https://reactome.org/PathwayBrowser/#/R-CEL-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 60430 R-CEL-1482861 https://reactome.org/PathwayBrowser/#/R-CEL-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Caenorhabditis elegans 60430 R-CEL-1482867 https://reactome.org/PathwayBrowser/#/R-CEL-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Caenorhabditis elegans 60430 R-CEL-1482894 https://reactome.org/PathwayBrowser/#/R-CEL-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Caenorhabditis elegans 60430 R-CFA-1482759 https://reactome.org/PathwayBrowser/#/R-CFA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Canis familiaris 60430 R-CFA-1482775 https://reactome.org/PathwayBrowser/#/R-CFA-1482775 MLCL is acylated to CL by HADH (IM) IEA Canis familiaris 60430 R-CFA-1482781 https://reactome.org/PathwayBrowser/#/R-CFA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Canis familiaris 60430 R-CFA-1482794 https://reactome.org/PathwayBrowser/#/R-CFA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Canis familiaris 60430 R-CFA-1482850 https://reactome.org/PathwayBrowser/#/R-CFA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Canis familiaris 60430 R-CFA-1482861 https://reactome.org/PathwayBrowser/#/R-CFA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Canis familiaris 60430 R-CFA-1482867 https://reactome.org/PathwayBrowser/#/R-CFA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Canis familiaris 60430 R-CFA-1482894 https://reactome.org/PathwayBrowser/#/R-CFA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Canis familiaris 60430 R-DDI-1482781 https://reactome.org/PathwayBrowser/#/R-DDI-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 60430 R-DDI-1482794 https://reactome.org/PathwayBrowser/#/R-DDI-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 60430 R-DDI-1482850 https://reactome.org/PathwayBrowser/#/R-DDI-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 60430 R-DDI-1482861 https://reactome.org/PathwayBrowser/#/R-DDI-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Dictyostelium discoideum 60430 R-DDI-1482867 https://reactome.org/PathwayBrowser/#/R-DDI-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Dictyostelium discoideum 60430 R-DDI-1482894 https://reactome.org/PathwayBrowser/#/R-DDI-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Dictyostelium discoideum 60430 R-DME-1482775 https://reactome.org/PathwayBrowser/#/R-DME-1482775 MLCL is acylated to CL by HADH (IM) IEA Drosophila melanogaster 60430 R-DME-1482781 https://reactome.org/PathwayBrowser/#/R-DME-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Drosophila melanogaster 60430 R-DME-1482794 https://reactome.org/PathwayBrowser/#/R-DME-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Drosophila melanogaster 60430 R-DME-1482850 https://reactome.org/PathwayBrowser/#/R-DME-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Drosophila melanogaster 60430 R-DME-1482894 https://reactome.org/PathwayBrowser/#/R-DME-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Drosophila melanogaster 60430 R-DRE-1482759 https://reactome.org/PathwayBrowser/#/R-DRE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Danio rerio 60430 R-DRE-1482775 https://reactome.org/PathwayBrowser/#/R-DRE-1482775 MLCL is acylated to CL by HADH (IM) IEA Danio rerio 60430 R-DRE-1482781 https://reactome.org/PathwayBrowser/#/R-DRE-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Danio rerio 60430 R-DRE-1482794 https://reactome.org/PathwayBrowser/#/R-DRE-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Danio rerio 60430 R-DRE-1482850 https://reactome.org/PathwayBrowser/#/R-DRE-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Danio rerio 60430 R-DRE-1482861 https://reactome.org/PathwayBrowser/#/R-DRE-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Danio rerio 60430 R-DRE-1482867 https://reactome.org/PathwayBrowser/#/R-DRE-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Danio rerio 60430 R-DRE-1482894 https://reactome.org/PathwayBrowser/#/R-DRE-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Danio rerio 60430 R-GGA-1482759 https://reactome.org/PathwayBrowser/#/R-GGA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Gallus gallus 60430 R-GGA-1482775 https://reactome.org/PathwayBrowser/#/R-GGA-1482775 MLCL is acylated to CL by HADH (IM) IEA Gallus gallus 60430 R-GGA-1482781 https://reactome.org/PathwayBrowser/#/R-GGA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Gallus gallus 60430 R-GGA-1482794 https://reactome.org/PathwayBrowser/#/R-GGA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Gallus gallus 60430 R-GGA-1482850 https://reactome.org/PathwayBrowser/#/R-GGA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Gallus gallus 60430 R-GGA-1482861 https://reactome.org/PathwayBrowser/#/R-GGA-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Gallus gallus 60430 R-GGA-1482867 https://reactome.org/PathwayBrowser/#/R-GGA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Gallus gallus 60430 R-GGA-1482894 https://reactome.org/PathwayBrowser/#/R-GGA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Gallus gallus 60430 R-HSA-1482759 https://reactome.org/PathwayBrowser/#/R-HSA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) TAS Homo sapiens 60430 R-HSA-1482773 https://reactome.org/PathwayBrowser/#/R-HSA-1482773 MLCL transports from the IM to the ER TAS Homo sapiens 60430 R-HSA-1482775 https://reactome.org/PathwayBrowser/#/R-HSA-1482775 MLCL is acylated to CL by HADH (IM) TAS Homo sapiens 60430 R-HSA-1482778 https://reactome.org/PathwayBrowser/#/R-HSA-1482778 CL is hydrolyzed to MLCL by PLA2G6 (IM) IEA Homo sapiens 60430 R-HSA-1482781 https://reactome.org/PathwayBrowser/#/R-HSA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) TAS Homo sapiens 60430 R-HSA-1482794 https://reactome.org/PathwayBrowser/#/R-HSA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) TAS Homo sapiens 60430 R-HSA-1482850 https://reactome.org/PathwayBrowser/#/R-HSA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) TAS Homo sapiens 60430 R-HSA-1482861 https://reactome.org/PathwayBrowser/#/R-HSA-1482861 MLCL is acylated to CL by LCLAT1 (ER) TAS Homo sapiens 60430 R-HSA-1482867 https://reactome.org/PathwayBrowser/#/R-HSA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) TAS Homo sapiens 60430 R-HSA-1482894 https://reactome.org/PathwayBrowser/#/R-HSA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) TAS Homo sapiens 60430 R-MMU-1482759 https://reactome.org/PathwayBrowser/#/R-MMU-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Mus musculus 60430 R-MMU-1482775 https://reactome.org/PathwayBrowser/#/R-MMU-1482775 MLCL is acylated to CL by HADH (IM) IEA Mus musculus 60430 R-MMU-1482781 https://reactome.org/PathwayBrowser/#/R-MMU-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Mus musculus 60430 R-MMU-1482794 https://reactome.org/PathwayBrowser/#/R-MMU-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Mus musculus 60430 R-MMU-1482850 https://reactome.org/PathwayBrowser/#/R-MMU-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Mus musculus 60430 R-MMU-1482861 https://reactome.org/PathwayBrowser/#/R-MMU-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Mus musculus 60430 R-MMU-1482867 https://reactome.org/PathwayBrowser/#/R-MMU-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Mus musculus 60430 R-MMU-1482894 https://reactome.org/PathwayBrowser/#/R-MMU-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Mus musculus 60430 R-RNO-1482759 https://reactome.org/PathwayBrowser/#/R-RNO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Rattus norvegicus 60430 R-RNO-1482775 https://reactome.org/PathwayBrowser/#/R-RNO-1482775 MLCL is acylated to CL by HADH (IM) IEA Rattus norvegicus 60430 R-RNO-1482781 https://reactome.org/PathwayBrowser/#/R-RNO-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Rattus norvegicus 60430 R-RNO-1482794 https://reactome.org/PathwayBrowser/#/R-RNO-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Rattus norvegicus 60430 R-RNO-1482836 https://reactome.org/PathwayBrowser/#/R-RNO-1482836 CL is hydrolyzed to MLCL by Pla2g6 (IM) TAS Rattus norvegicus 60430 R-RNO-1482850 https://reactome.org/PathwayBrowser/#/R-RNO-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Rattus norvegicus 60430 R-RNO-1482861 https://reactome.org/PathwayBrowser/#/R-RNO-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Rattus norvegicus 60430 R-RNO-1482867 https://reactome.org/PathwayBrowser/#/R-RNO-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Rattus norvegicus 60430 R-RNO-1482894 https://reactome.org/PathwayBrowser/#/R-RNO-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Rattus norvegicus 60430 R-SCE-1482759 https://reactome.org/PathwayBrowser/#/R-SCE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Saccharomyces cerevisiae 60430 R-SCE-1482781 https://reactome.org/PathwayBrowser/#/R-SCE-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 60430 R-SCE-1482794 https://reactome.org/PathwayBrowser/#/R-SCE-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 60430 R-SCE-1482850 https://reactome.org/PathwayBrowser/#/R-SCE-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 60430 R-SCE-1482861 https://reactome.org/PathwayBrowser/#/R-SCE-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Saccharomyces cerevisiae 60430 R-SCE-1482867 https://reactome.org/PathwayBrowser/#/R-SCE-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Saccharomyces cerevisiae 60430 R-SCE-1482894 https://reactome.org/PathwayBrowser/#/R-SCE-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Saccharomyces cerevisiae 60430 R-SPO-1482759 https://reactome.org/PathwayBrowser/#/R-SPO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Schizosaccharomyces pombe 60430 R-SPO-1482861 https://reactome.org/PathwayBrowser/#/R-SPO-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Schizosaccharomyces pombe 60430 R-SPO-1482867 https://reactome.org/PathwayBrowser/#/R-SPO-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Schizosaccharomyces pombe 60430 R-SSC-1482759 https://reactome.org/PathwayBrowser/#/R-SSC-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Sus scrofa 60430 R-SSC-1482775 https://reactome.org/PathwayBrowser/#/R-SSC-1482775 MLCL is acylated to CL by HADH (IM) IEA Sus scrofa 60430 R-SSC-1482781 https://reactome.org/PathwayBrowser/#/R-SSC-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Sus scrofa 60430 R-SSC-1482794 https://reactome.org/PathwayBrowser/#/R-SSC-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Sus scrofa 60430 R-SSC-1482850 https://reactome.org/PathwayBrowser/#/R-SSC-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Sus scrofa 60430 R-SSC-1482861 https://reactome.org/PathwayBrowser/#/R-SSC-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Sus scrofa 60430 R-SSC-1482867 https://reactome.org/PathwayBrowser/#/R-SSC-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Sus scrofa 60430 R-SSC-1482894 https://reactome.org/PathwayBrowser/#/R-SSC-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Sus scrofa 60430 R-XTR-1482759 https://reactome.org/PathwayBrowser/#/R-XTR-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Xenopus tropicalis 60430 R-XTR-1482775 https://reactome.org/PathwayBrowser/#/R-XTR-1482775 MLCL is acylated to CL by HADH (IM) IEA Xenopus tropicalis 60430 R-XTR-1482781 https://reactome.org/PathwayBrowser/#/R-XTR-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Xenopus tropicalis 60430 R-XTR-1482794 https://reactome.org/PathwayBrowser/#/R-XTR-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Xenopus tropicalis 60430 R-XTR-1482850 https://reactome.org/PathwayBrowser/#/R-XTR-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Xenopus tropicalis 60430 R-XTR-1482861 https://reactome.org/PathwayBrowser/#/R-XTR-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Xenopus tropicalis 60430 R-XTR-1482867 https://reactome.org/PathwayBrowser/#/R-XTR-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Xenopus tropicalis 60430 R-XTR-1482894 https://reactome.org/PathwayBrowser/#/R-XTR-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Xenopus tropicalis 60453 R-BTA-8850356 https://reactome.org/PathwayBrowser/#/R-BTA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Bos taurus 60453 R-CFA-8850356 https://reactome.org/PathwayBrowser/#/R-CFA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Canis familiaris 60453 R-GGA-8850356 https://reactome.org/PathwayBrowser/#/R-GGA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Gallus gallus 60453 R-HSA-8850356 https://reactome.org/PathwayBrowser/#/R-HSA-8850356 TCR binds microbial lipid-based antigen via CD1 TAS Homo sapiens 60453 R-MMU-8850356 https://reactome.org/PathwayBrowser/#/R-MMU-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Mus musculus 60453 R-RNO-8850356 https://reactome.org/PathwayBrowser/#/R-RNO-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Rattus norvegicus 60453 R-SSC-8850356 https://reactome.org/PathwayBrowser/#/R-SSC-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Sus scrofa 60471 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 60471 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 60471 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 60471 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 60471 R-BTA-73635 https://reactome.org/PathwayBrowser/#/R-BTA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Bos taurus 60471 R-BTA-75126 https://reactome.org/PathwayBrowser/#/R-BTA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Bos taurus 60471 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 60471 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 60471 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 60471 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 60471 R-CEL-73635 https://reactome.org/PathwayBrowser/#/R-CEL-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Caenorhabditis elegans 60471 R-CEL-75126 https://reactome.org/PathwayBrowser/#/R-CEL-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Caenorhabditis elegans 60471 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 60471 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 60471 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 60471 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 60471 R-CFA-73635 https://reactome.org/PathwayBrowser/#/R-CFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Canis familiaris 60471 R-CFA-75126 https://reactome.org/PathwayBrowser/#/R-CFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Canis familiaris 60471 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 60471 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 60471 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 60471 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 60471 R-DDI-73635 https://reactome.org/PathwayBrowser/#/R-DDI-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Dictyostelium discoideum 60471 R-DDI-75126 https://reactome.org/PathwayBrowser/#/R-DDI-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Dictyostelium discoideum 60471 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 60471 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 60471 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 60471 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 60471 R-DME-73635 https://reactome.org/PathwayBrowser/#/R-DME-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Drosophila melanogaster 60471 R-DME-75126 https://reactome.org/PathwayBrowser/#/R-DME-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Drosophila melanogaster 60471 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 60471 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 60471 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 60471 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 60471 R-DRE-73635 https://reactome.org/PathwayBrowser/#/R-DRE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Danio rerio 60471 R-DRE-75126 https://reactome.org/PathwayBrowser/#/R-DRE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Danio rerio 60471 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 60471 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 60471 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 60471 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 60471 R-GGA-73635 https://reactome.org/PathwayBrowser/#/R-GGA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Gallus gallus 60471 R-GGA-75126 https://reactome.org/PathwayBrowser/#/R-GGA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Gallus gallus 60471 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 60471 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 60471 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 60471 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 60471 R-HSA-73635 https://reactome.org/PathwayBrowser/#/R-HSA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] TAS Homo sapiens 60471 R-HSA-75126 https://reactome.org/PathwayBrowser/#/R-HSA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] TAS Homo sapiens 60471 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 60471 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 60471 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 60471 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 60471 R-MMU-73635 https://reactome.org/PathwayBrowser/#/R-MMU-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Mus musculus 60471 R-MMU-75126 https://reactome.org/PathwayBrowser/#/R-MMU-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Mus musculus 60471 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 60471 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 60471 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 60471 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 60471 R-PFA-73635 https://reactome.org/PathwayBrowser/#/R-PFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Plasmodium falciparum 60471 R-PFA-75126 https://reactome.org/PathwayBrowser/#/R-PFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Plasmodium falciparum 60471 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 60471 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 60471 R-RNO-73635 https://reactome.org/PathwayBrowser/#/R-RNO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Rattus norvegicus 60471 R-RNO-75126 https://reactome.org/PathwayBrowser/#/R-RNO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Rattus norvegicus 60471 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 60471 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 60471 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 60471 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 60471 R-SCE-73635 https://reactome.org/PathwayBrowser/#/R-SCE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Saccharomyces cerevisiae 60471 R-SCE-75126 https://reactome.org/PathwayBrowser/#/R-SCE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Saccharomyces cerevisiae 60471 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 60471 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 60471 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 60471 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 60471 R-SPO-73635 https://reactome.org/PathwayBrowser/#/R-SPO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Schizosaccharomyces pombe 60471 R-SPO-75126 https://reactome.org/PathwayBrowser/#/R-SPO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Schizosaccharomyces pombe 60471 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 60471 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 60471 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 60471 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 60471 R-SSC-73635 https://reactome.org/PathwayBrowser/#/R-SSC-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Sus scrofa 60471 R-SSC-75126 https://reactome.org/PathwayBrowser/#/R-SSC-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Sus scrofa 60471 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 60471 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 60471 R-XTR-73635 https://reactome.org/PathwayBrowser/#/R-XTR-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Xenopus tropicalis 60471 R-XTR-75126 https://reactome.org/PathwayBrowser/#/R-XTR-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Xenopus tropicalis 60473 R-BTA-200644 https://reactome.org/PathwayBrowser/#/R-BTA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Bos taurus 60473 R-BTA-200651 https://reactome.org/PathwayBrowser/#/R-BTA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Bos taurus 60473 R-BTA-200676 https://reactome.org/PathwayBrowser/#/R-BTA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Bos taurus 60473 R-BTA-200718 https://reactome.org/PathwayBrowser/#/R-BTA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Bos taurus 60473 R-BTA-200735 https://reactome.org/PathwayBrowser/#/R-BTA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Bos taurus 60473 R-CEL-200644 https://reactome.org/PathwayBrowser/#/R-CEL-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Caenorhabditis elegans 60473 R-CEL-200651 https://reactome.org/PathwayBrowser/#/R-CEL-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Caenorhabditis elegans 60473 R-CEL-200676 https://reactome.org/PathwayBrowser/#/R-CEL-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Caenorhabditis elegans 60473 R-CEL-200718 https://reactome.org/PathwayBrowser/#/R-CEL-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Caenorhabditis elegans 60473 R-CEL-200735 https://reactome.org/PathwayBrowser/#/R-CEL-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Caenorhabditis elegans 60473 R-CFA-200644 https://reactome.org/PathwayBrowser/#/R-CFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Canis familiaris 60473 R-CFA-200651 https://reactome.org/PathwayBrowser/#/R-CFA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Canis familiaris 60473 R-CFA-200676 https://reactome.org/PathwayBrowser/#/R-CFA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Canis familiaris 60473 R-CFA-200718 https://reactome.org/PathwayBrowser/#/R-CFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Canis familiaris 60473 R-CFA-200735 https://reactome.org/PathwayBrowser/#/R-CFA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Canis familiaris 60473 R-DDI-200644 https://reactome.org/PathwayBrowser/#/R-DDI-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Dictyostelium discoideum 60473 R-DDI-200651 https://reactome.org/PathwayBrowser/#/R-DDI-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Dictyostelium discoideum 60473 R-DDI-200676 https://reactome.org/PathwayBrowser/#/R-DDI-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Dictyostelium discoideum 60473 R-DDI-200718 https://reactome.org/PathwayBrowser/#/R-DDI-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Dictyostelium discoideum 60473 R-DDI-200735 https://reactome.org/PathwayBrowser/#/R-DDI-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Dictyostelium discoideum 60473 R-DME-200644 https://reactome.org/PathwayBrowser/#/R-DME-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Drosophila melanogaster 60473 R-DME-200651 https://reactome.org/PathwayBrowser/#/R-DME-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Drosophila melanogaster 60473 R-DME-200676 https://reactome.org/PathwayBrowser/#/R-DME-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Drosophila melanogaster 60473 R-DME-200718 https://reactome.org/PathwayBrowser/#/R-DME-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Drosophila melanogaster 60473 R-DME-200735 https://reactome.org/PathwayBrowser/#/R-DME-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Drosophila melanogaster 60473 R-DRE-200644 https://reactome.org/PathwayBrowser/#/R-DRE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Danio rerio 60473 R-DRE-200651 https://reactome.org/PathwayBrowser/#/R-DRE-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Danio rerio 60473 R-DRE-200676 https://reactome.org/PathwayBrowser/#/R-DRE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Danio rerio 60473 R-DRE-200718 https://reactome.org/PathwayBrowser/#/R-DRE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Danio rerio 60473 R-DRE-200735 https://reactome.org/PathwayBrowser/#/R-DRE-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Danio rerio 60473 R-GGA-200644 https://reactome.org/PathwayBrowser/#/R-GGA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Gallus gallus 60473 R-GGA-200651 https://reactome.org/PathwayBrowser/#/R-GGA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Gallus gallus 60473 R-GGA-200676 https://reactome.org/PathwayBrowser/#/R-GGA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Gallus gallus 60473 R-GGA-200718 https://reactome.org/PathwayBrowser/#/R-GGA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Gallus gallus 60473 R-GGA-200735 https://reactome.org/PathwayBrowser/#/R-GGA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Gallus gallus 60473 R-HSA-200644 https://reactome.org/PathwayBrowser/#/R-HSA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ TAS Homo sapiens 60473 R-HSA-200651 https://reactome.org/PathwayBrowser/#/R-HSA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine TAS Homo sapiens 60473 R-HSA-200676 https://reactome.org/PathwayBrowser/#/R-HSA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG TAS Homo sapiens 60473 R-HSA-200718 https://reactome.org/PathwayBrowser/#/R-HSA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG TAS Homo sapiens 60473 R-HSA-200735 https://reactome.org/PathwayBrowser/#/R-HSA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG TAS Homo sapiens 60473 R-MMU-200644 https://reactome.org/PathwayBrowser/#/R-MMU-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Mus musculus 60473 R-MMU-200651 https://reactome.org/PathwayBrowser/#/R-MMU-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Mus musculus 60473 R-MMU-200676 https://reactome.org/PathwayBrowser/#/R-MMU-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Mus musculus 60473 R-MMU-200718 https://reactome.org/PathwayBrowser/#/R-MMU-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Mus musculus 60473 R-MMU-200735 https://reactome.org/PathwayBrowser/#/R-MMU-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Mus musculus 60473 R-PFA-200644 https://reactome.org/PathwayBrowser/#/R-PFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Plasmodium falciparum 60473 R-PFA-200651 https://reactome.org/PathwayBrowser/#/R-PFA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Plasmodium falciparum 60473 R-PFA-200718 https://reactome.org/PathwayBrowser/#/R-PFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Plasmodium falciparum 60473 R-PFA-200735 https://reactome.org/PathwayBrowser/#/R-PFA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Plasmodium falciparum 60473 R-RNO-200644 https://reactome.org/PathwayBrowser/#/R-RNO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Rattus norvegicus 60473 R-RNO-200651 https://reactome.org/PathwayBrowser/#/R-RNO-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Rattus norvegicus 60473 R-RNO-200676 https://reactome.org/PathwayBrowser/#/R-RNO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Rattus norvegicus 60473 R-RNO-200718 https://reactome.org/PathwayBrowser/#/R-RNO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Rattus norvegicus 60473 R-RNO-200735 https://reactome.org/PathwayBrowser/#/R-RNO-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Rattus norvegicus 60473 R-SCE-200644 https://reactome.org/PathwayBrowser/#/R-SCE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Saccharomyces cerevisiae 60473 R-SCE-200676 https://reactome.org/PathwayBrowser/#/R-SCE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Saccharomyces cerevisiae 60473 R-SCE-200718 https://reactome.org/PathwayBrowser/#/R-SCE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Saccharomyces cerevisiae 60473 R-SPO-200644 https://reactome.org/PathwayBrowser/#/R-SPO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Schizosaccharomyces pombe 60473 R-SPO-200676 https://reactome.org/PathwayBrowser/#/R-SPO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Schizosaccharomyces pombe 60473 R-SPO-200718 https://reactome.org/PathwayBrowser/#/R-SPO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Schizosaccharomyces pombe 60473 R-SSC-200644 https://reactome.org/PathwayBrowser/#/R-SSC-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Sus scrofa 60473 R-SSC-200651 https://reactome.org/PathwayBrowser/#/R-SSC-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Sus scrofa 60473 R-SSC-200676 https://reactome.org/PathwayBrowser/#/R-SSC-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Sus scrofa 60473 R-SSC-200718 https://reactome.org/PathwayBrowser/#/R-SSC-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Sus scrofa 60473 R-SSC-200735 https://reactome.org/PathwayBrowser/#/R-SSC-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Sus scrofa 60473 R-XTR-200644 https://reactome.org/PathwayBrowser/#/R-XTR-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Xenopus tropicalis 60473 R-XTR-200651 https://reactome.org/PathwayBrowser/#/R-XTR-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Xenopus tropicalis 60473 R-XTR-200676 https://reactome.org/PathwayBrowser/#/R-XTR-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Xenopus tropicalis 60473 R-XTR-200718 https://reactome.org/PathwayBrowser/#/R-XTR-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Xenopus tropicalis 60473 R-XTR-200735 https://reactome.org/PathwayBrowser/#/R-XTR-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Xenopus tropicalis 60479 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 60479 R-BTA-2197646 https://reactome.org/PathwayBrowser/#/R-BTA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Bos taurus 60479 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 60479 R-BTA-2512800 https://reactome.org/PathwayBrowser/#/R-BTA-2512800 SCARB1:ligand is endocytosed IEA Bos taurus 60479 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 60479 R-BTA-6814797 https://reactome.org/PathwayBrowser/#/R-BTA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Bos taurus 60479 R-BTA-8869667 https://reactome.org/PathwayBrowser/#/R-BTA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Bos taurus 60479 R-BTA-8952251 https://reactome.org/PathwayBrowser/#/R-BTA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Bos taurus 60479 R-CEL-6814797 https://reactome.org/PathwayBrowser/#/R-CEL-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Caenorhabditis elegans 60479 R-CEL-8952251 https://reactome.org/PathwayBrowser/#/R-CEL-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Caenorhabditis elegans 60479 R-CFA-2197646 https://reactome.org/PathwayBrowser/#/R-CFA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Canis familiaris 60479 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 60479 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 60479 R-CFA-2512800 https://reactome.org/PathwayBrowser/#/R-CFA-2512800 SCARB1:ligand is endocytosed IEA Canis familiaris 60479 R-CFA-6814797 https://reactome.org/PathwayBrowser/#/R-CFA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Canis familiaris 60479 R-CFA-8952251 https://reactome.org/PathwayBrowser/#/R-CFA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Canis familiaris 60479 R-DDI-6814797 https://reactome.org/PathwayBrowser/#/R-DDI-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Dictyostelium discoideum 60479 R-DME-8952251 https://reactome.org/PathwayBrowser/#/R-DME-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Drosophila melanogaster 60479 R-DRE-6814797 https://reactome.org/PathwayBrowser/#/R-DRE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Danio rerio 60479 R-GGA-2197646 https://reactome.org/PathwayBrowser/#/R-GGA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Gallus gallus 60479 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 60479 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 60479 R-GGA-2512800 https://reactome.org/PathwayBrowser/#/R-GGA-2512800 SCARB1:ligand is endocytosed IEA Gallus gallus 60479 R-GGA-6814797 https://reactome.org/PathwayBrowser/#/R-GGA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Gallus gallus 60479 R-GGA-8869667 https://reactome.org/PathwayBrowser/#/R-GGA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Gallus gallus 60479 R-GGA-8952251 https://reactome.org/PathwayBrowser/#/R-GGA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Gallus gallus 60479 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 60479 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 60479 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 60479 R-HSA-2197645 https://reactome.org/PathwayBrowser/#/R-HSA-2197645 SCARF1 (SREC-I) binds ligands IEA Homo sapiens 60479 R-HSA-2197646 https://reactome.org/PathwayBrowser/#/R-HSA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands TAS Homo sapiens 60479 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 60479 R-HSA-2247514 https://reactome.org/PathwayBrowser/#/R-HSA-2247514 SCARF1:ligand is endocytosed TAS Homo sapiens 60479 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 60479 R-HSA-2512800 https://reactome.org/PathwayBrowser/#/R-HSA-2512800 SCARB1:ligand is endocytosed TAS Homo sapiens 60479 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 60479 R-HSA-6814797 https://reactome.org/PathwayBrowser/#/R-HSA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine TAS Homo sapiens 60479 R-HSA-8869667 https://reactome.org/PathwayBrowser/#/R-HSA-8869667 oxLDL:CD36 binds TLR4:TLR6 TAS Homo sapiens 60479 R-HSA-8952251 https://reactome.org/PathwayBrowser/#/R-HSA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) TAS Homo sapiens 60479 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 60479 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 60479 R-MMU-2197646 https://reactome.org/PathwayBrowser/#/R-MMU-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Mus musculus 60479 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 60479 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 60479 R-MMU-2512800 https://reactome.org/PathwayBrowser/#/R-MMU-2512800 SCARB1:ligand is endocytosed IEA Mus musculus 60479 R-MMU-6814797 https://reactome.org/PathwayBrowser/#/R-MMU-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Mus musculus 60479 R-MMU-8869667 https://reactome.org/PathwayBrowser/#/R-MMU-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Mus musculus 60479 R-MMU-8952251 https://reactome.org/PathwayBrowser/#/R-MMU-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Mus musculus 60479 R-RNO-2197646 https://reactome.org/PathwayBrowser/#/R-RNO-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Rattus norvegicus 60479 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 60479 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 60479 R-RNO-2512800 https://reactome.org/PathwayBrowser/#/R-RNO-2512800 SCARB1:ligand is endocytosed IEA Rattus norvegicus 60479 R-RNO-6814797 https://reactome.org/PathwayBrowser/#/R-RNO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Rattus norvegicus 60479 R-RNO-8869667 https://reactome.org/PathwayBrowser/#/R-RNO-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Rattus norvegicus 60479 R-RNO-8952251 https://reactome.org/PathwayBrowser/#/R-RNO-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Rattus norvegicus 60479 R-SCE-6814797 https://reactome.org/PathwayBrowser/#/R-SCE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Saccharomyces cerevisiae 60479 R-SCE-8952251 https://reactome.org/PathwayBrowser/#/R-SCE-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Saccharomyces cerevisiae 60479 R-SPO-6814797 https://reactome.org/PathwayBrowser/#/R-SPO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Schizosaccharomyces pombe 60479 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa 60479 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 60479 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 60479 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa 60479 R-SSC-6814797 https://reactome.org/PathwayBrowser/#/R-SSC-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Sus scrofa 60479 R-SSC-8869667 https://reactome.org/PathwayBrowser/#/R-SSC-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Sus scrofa 60479 R-SSC-8952251 https://reactome.org/PathwayBrowser/#/R-SSC-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Sus scrofa 60479 R-XTR-6814797 https://reactome.org/PathwayBrowser/#/R-XTR-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Xenopus tropicalis 60479 R-XTR-8952251 https://reactome.org/PathwayBrowser/#/R-XTR-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Xenopus tropicalis 60488 R-BTA-174374 https://reactome.org/PathwayBrowser/#/R-BTA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Bos taurus 60488 R-BTA-3095889 https://reactome.org/PathwayBrowser/#/R-BTA-3095889 MMACHC dealkylates RCbl IEA Bos taurus 60488 R-BTA-3149539 https://reactome.org/PathwayBrowser/#/R-BTA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Bos taurus 60488 R-BTA-9759549 https://reactome.org/PathwayBrowser/#/R-BTA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Bos taurus 60488 R-CEL-174374 https://reactome.org/PathwayBrowser/#/R-CEL-174374 MTR transfers CH3 from MeCbl to HCYS IEA Caenorhabditis elegans 60488 R-CEL-3095889 https://reactome.org/PathwayBrowser/#/R-CEL-3095889 MMACHC dealkylates RCbl IEA Caenorhabditis elegans 60488 R-CEL-3149539 https://reactome.org/PathwayBrowser/#/R-CEL-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Caenorhabditis elegans 60488 R-CEL-9759549 https://reactome.org/PathwayBrowser/#/R-CEL-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Caenorhabditis elegans 60488 R-CFA-174374 https://reactome.org/PathwayBrowser/#/R-CFA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Canis familiaris 60488 R-CFA-3095889 https://reactome.org/PathwayBrowser/#/R-CFA-3095889 MMACHC dealkylates RCbl IEA Canis familiaris 60488 R-CFA-3149539 https://reactome.org/PathwayBrowser/#/R-CFA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Canis familiaris 60488 R-CFA-9759549 https://reactome.org/PathwayBrowser/#/R-CFA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Canis familiaris 60488 R-DDI-174374 https://reactome.org/PathwayBrowser/#/R-DDI-174374 MTR transfers CH3 from MeCbl to HCYS IEA Dictyostelium discoideum 60488 R-DDI-3095889 https://reactome.org/PathwayBrowser/#/R-DDI-3095889 MMACHC dealkylates RCbl IEA Dictyostelium discoideum 60488 R-DDI-3149539 https://reactome.org/PathwayBrowser/#/R-DDI-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Dictyostelium discoideum 60488 R-DDI-9759549 https://reactome.org/PathwayBrowser/#/R-DDI-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Dictyostelium discoideum 60488 R-DRE-3095889 https://reactome.org/PathwayBrowser/#/R-DRE-3095889 MMACHC dealkylates RCbl IEA Danio rerio 60488 R-DRE-9759549 https://reactome.org/PathwayBrowser/#/R-DRE-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Danio rerio 60488 R-GGA-174374 https://reactome.org/PathwayBrowser/#/R-GGA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Gallus gallus 60488 R-GGA-3095889 https://reactome.org/PathwayBrowser/#/R-GGA-3095889 MMACHC dealkylates RCbl IEA Gallus gallus 60488 R-GGA-3149539 https://reactome.org/PathwayBrowser/#/R-GGA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Gallus gallus 60488 R-GGA-9759549 https://reactome.org/PathwayBrowser/#/R-GGA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Gallus gallus 60488 R-HSA-174374 https://reactome.org/PathwayBrowser/#/R-HSA-174374 MTR transfers CH3 from MeCbl to HCYS TAS Homo sapiens 60488 R-HSA-3095889 https://reactome.org/PathwayBrowser/#/R-HSA-3095889 MMACHC dealkylates RCbl TAS Homo sapiens 60488 R-HSA-3149539 https://reactome.org/PathwayBrowser/#/R-HSA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin TAS Homo sapiens 60488 R-HSA-3321918 https://reactome.org/PathwayBrowser/#/R-HSA-3321918 Defective MTR does not transfer CH3 group from MTHF to cob(I)alamin TAS Homo sapiens 60488 R-HSA-3322125 https://reactome.org/PathwayBrowser/#/R-HSA-3322125 Defective MMAB does not transfer adenosyl group from ATP to B12s TAS Homo sapiens 60488 R-HSA-9759549 https://reactome.org/PathwayBrowser/#/R-HSA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin TAS Homo sapiens 60488 R-MMU-174374 https://reactome.org/PathwayBrowser/#/R-MMU-174374 MTR transfers CH3 from MeCbl to HCYS IEA Mus musculus 60488 R-MMU-3095889 https://reactome.org/PathwayBrowser/#/R-MMU-3095889 MMACHC dealkylates RCbl IEA Mus musculus 60488 R-MMU-3149539 https://reactome.org/PathwayBrowser/#/R-MMU-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Mus musculus 60488 R-MMU-9759549 https://reactome.org/PathwayBrowser/#/R-MMU-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Mus musculus 60488 R-RNO-174374 https://reactome.org/PathwayBrowser/#/R-RNO-174374 MTR transfers CH3 from MeCbl to HCYS IEA Rattus norvegicus 60488 R-RNO-3095889 https://reactome.org/PathwayBrowser/#/R-RNO-3095889 MMACHC dealkylates RCbl IEA Rattus norvegicus 60488 R-RNO-3149539 https://reactome.org/PathwayBrowser/#/R-RNO-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Rattus norvegicus 60488 R-RNO-9759549 https://reactome.org/PathwayBrowser/#/R-RNO-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Rattus norvegicus 60488 R-SSC-174374 https://reactome.org/PathwayBrowser/#/R-SSC-174374 MTR transfers CH3 from MeCbl to HCYS IEA Sus scrofa 60488 R-SSC-3095889 https://reactome.org/PathwayBrowser/#/R-SSC-3095889 MMACHC dealkylates RCbl IEA Sus scrofa 60488 R-SSC-3149539 https://reactome.org/PathwayBrowser/#/R-SSC-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Sus scrofa 60488 R-SSC-9759549 https://reactome.org/PathwayBrowser/#/R-SSC-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Sus scrofa 60488 R-XTR-3095889 https://reactome.org/PathwayBrowser/#/R-XTR-3095889 MMACHC dealkylates RCbl IEA Xenopus tropicalis 60488 R-XTR-9759549 https://reactome.org/PathwayBrowser/#/R-XTR-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Xenopus tropicalis 60530 R-BTA-2995330 https://reactome.org/PathwayBrowser/#/R-BTA-2995330 COX10 transforms heme to heme O IEA Bos taurus 60530 R-BTA-2995334 https://reactome.org/PathwayBrowser/#/R-BTA-2995334 COX15 transforms heme O to heme A IEA Bos taurus 60530 R-CEL-2995330 https://reactome.org/PathwayBrowser/#/R-CEL-2995330 COX10 transforms heme to heme O IEA Caenorhabditis elegans 60530 R-CEL-2995334 https://reactome.org/PathwayBrowser/#/R-CEL-2995334 COX15 transforms heme O to heme A IEA Caenorhabditis elegans 60530 R-CFA-2995330 https://reactome.org/PathwayBrowser/#/R-CFA-2995330 COX10 transforms heme to heme O IEA Canis familiaris 60530 R-CFA-2995334 https://reactome.org/PathwayBrowser/#/R-CFA-2995334 COX15 transforms heme O to heme A IEA Canis familiaris 60530 R-DDI-2995330 https://reactome.org/PathwayBrowser/#/R-DDI-2995330 COX10 transforms heme to heme O IEA Dictyostelium discoideum 60530 R-DDI-2995334 https://reactome.org/PathwayBrowser/#/R-DDI-2995334 COX15 transforms heme O to heme A IEA Dictyostelium discoideum 60530 R-DME-2995330 https://reactome.org/PathwayBrowser/#/R-DME-2995330 COX10 transforms heme to heme O IEA Drosophila melanogaster 60530 R-DME-2995334 https://reactome.org/PathwayBrowser/#/R-DME-2995334 COX15 transforms heme O to heme A IEA Drosophila melanogaster 60530 R-GGA-2995330 https://reactome.org/PathwayBrowser/#/R-GGA-2995330 COX10 transforms heme to heme O IEA Gallus gallus 60530 R-GGA-2995334 https://reactome.org/PathwayBrowser/#/R-GGA-2995334 COX15 transforms heme O to heme A IEA Gallus gallus 60530 R-HSA-2995330 https://reactome.org/PathwayBrowser/#/R-HSA-2995330 COX10 transforms heme to heme O TAS Homo sapiens 60530 R-HSA-2995334 https://reactome.org/PathwayBrowser/#/R-HSA-2995334 COX15 transforms heme O to heme A TAS Homo sapiens 60530 R-MMU-2995330 https://reactome.org/PathwayBrowser/#/R-MMU-2995330 COX10 transforms heme to heme O IEA Mus musculus 60530 R-MMU-2995334 https://reactome.org/PathwayBrowser/#/R-MMU-2995334 COX15 transforms heme O to heme A IEA Mus musculus 60530 R-PFA-2995330 https://reactome.org/PathwayBrowser/#/R-PFA-2995330 COX10 transforms heme to heme O IEA Plasmodium falciparum 60530 R-PFA-2995334 https://reactome.org/PathwayBrowser/#/R-PFA-2995334 COX15 transforms heme O to heme A IEA Plasmodium falciparum 60530 R-RNO-2995330 https://reactome.org/PathwayBrowser/#/R-RNO-2995330 COX10 transforms heme to heme O IEA Rattus norvegicus 60530 R-RNO-2995334 https://reactome.org/PathwayBrowser/#/R-RNO-2995334 COX15 transforms heme O to heme A IEA Rattus norvegicus 60530 R-SCE-2995330 https://reactome.org/PathwayBrowser/#/R-SCE-2995330 COX10 transforms heme to heme O IEA Saccharomyces cerevisiae 60530 R-SCE-2995334 https://reactome.org/PathwayBrowser/#/R-SCE-2995334 COX15 transforms heme O to heme A IEA Saccharomyces cerevisiae 60530 R-SPO-2995330 https://reactome.org/PathwayBrowser/#/R-SPO-2995330 COX10 transforms heme to heme O IEA Schizosaccharomyces pombe 60530 R-SPO-2995334 https://reactome.org/PathwayBrowser/#/R-SPO-2995334 COX15 transforms heme O to heme A IEA Schizosaccharomyces pombe 60530 R-SSC-2995330 https://reactome.org/PathwayBrowser/#/R-SSC-2995330 COX10 transforms heme to heme O IEA Sus scrofa 60530 R-SSC-2995334 https://reactome.org/PathwayBrowser/#/R-SSC-2995334 COX15 transforms heme O to heme A IEA Sus scrofa 60530 R-XTR-2995330 https://reactome.org/PathwayBrowser/#/R-XTR-2995330 COX10 transforms heme to heme O IEA Xenopus tropicalis 60530 R-XTR-2995334 https://reactome.org/PathwayBrowser/#/R-XTR-2995334 COX15 transforms heme O to heme A IEA Xenopus tropicalis 60615 R-BTA-975814 https://reactome.org/PathwayBrowser/#/R-BTA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Bos taurus 60615 R-BTA-975829 https://reactome.org/PathwayBrowser/#/R-BTA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Bos taurus 60615 R-CEL-975814 https://reactome.org/PathwayBrowser/#/R-CEL-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Caenorhabditis elegans 60615 R-CEL-975829 https://reactome.org/PathwayBrowser/#/R-CEL-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Caenorhabditis elegans 60615 R-CFA-975814 https://reactome.org/PathwayBrowser/#/R-CFA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Canis familiaris 60615 R-CFA-975829 https://reactome.org/PathwayBrowser/#/R-CFA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Canis familiaris 60615 R-DME-975814 https://reactome.org/PathwayBrowser/#/R-DME-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Drosophila melanogaster 60615 R-DME-975829 https://reactome.org/PathwayBrowser/#/R-DME-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Drosophila melanogaster 60615 R-DRE-975829 https://reactome.org/PathwayBrowser/#/R-DRE-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Danio rerio 60615 R-GGA-975814 https://reactome.org/PathwayBrowser/#/R-GGA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Gallus gallus 60615 R-GGA-975829 https://reactome.org/PathwayBrowser/#/R-GGA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Gallus gallus 60615 R-HSA-4793955 https://reactome.org/PathwayBrowser/#/R-HSA-4793955 Defective MGAT2 does not transfer GlcNAc to N-glycans TAS Homo sapiens 60615 R-HSA-975814 https://reactome.org/PathwayBrowser/#/R-HSA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 TAS Homo sapiens 60615 R-HSA-975829 https://reactome.org/PathwayBrowser/#/R-HSA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 TAS Homo sapiens 60615 R-MMU-975814 https://reactome.org/PathwayBrowser/#/R-MMU-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Mus musculus 60615 R-MMU-975829 https://reactome.org/PathwayBrowser/#/R-MMU-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Mus musculus 60615 R-RNO-975814 https://reactome.org/PathwayBrowser/#/R-RNO-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Rattus norvegicus 60615 R-RNO-975829 https://reactome.org/PathwayBrowser/#/R-RNO-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Rattus norvegicus 60615 R-SSC-975814 https://reactome.org/PathwayBrowser/#/R-SSC-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Sus scrofa 60615 R-SSC-975829 https://reactome.org/PathwayBrowser/#/R-SSC-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Sus scrofa 60615 R-XTR-975814 https://reactome.org/PathwayBrowser/#/R-XTR-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Xenopus tropicalis 60615 R-XTR-975829 https://reactome.org/PathwayBrowser/#/R-XTR-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Xenopus tropicalis 60625 R-BTA-964768 https://reactome.org/PathwayBrowser/#/R-BTA-964768 Addition of GlcNAc to the glycan on the A arm IEA Bos taurus 60625 R-BTA-975814 https://reactome.org/PathwayBrowser/#/R-BTA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Bos taurus 60625 R-CEL-964768 https://reactome.org/PathwayBrowser/#/R-CEL-964768 Addition of GlcNAc to the glycan on the A arm IEA Caenorhabditis elegans 60625 R-CEL-975814 https://reactome.org/PathwayBrowser/#/R-CEL-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Caenorhabditis elegans 60625 R-CFA-975814 https://reactome.org/PathwayBrowser/#/R-CFA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Canis familiaris 60625 R-DDI-964768 https://reactome.org/PathwayBrowser/#/R-DDI-964768 Addition of GlcNAc to the glycan on the A arm IEA Dictyostelium discoideum 60625 R-DME-964768 https://reactome.org/PathwayBrowser/#/R-DME-964768 Addition of GlcNAc to the glycan on the A arm IEA Drosophila melanogaster 60625 R-DME-975814 https://reactome.org/PathwayBrowser/#/R-DME-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Drosophila melanogaster 60625 R-DRE-964768 https://reactome.org/PathwayBrowser/#/R-DRE-964768 Addition of GlcNAc to the glycan on the A arm IEA Danio rerio 60625 R-GGA-964768 https://reactome.org/PathwayBrowser/#/R-GGA-964768 Addition of GlcNAc to the glycan on the A arm IEA Gallus gallus 60625 R-GGA-975814 https://reactome.org/PathwayBrowser/#/R-GGA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Gallus gallus 60625 R-HSA-964768 https://reactome.org/PathwayBrowser/#/R-HSA-964768 Addition of GlcNAc to the glycan on the A arm TAS Homo sapiens 60625 R-HSA-975814 https://reactome.org/PathwayBrowser/#/R-HSA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 TAS Homo sapiens 60625 R-MMU-964768 https://reactome.org/PathwayBrowser/#/R-MMU-964768 Addition of GlcNAc to the glycan on the A arm IEA Mus musculus 60625 R-MMU-975814 https://reactome.org/PathwayBrowser/#/R-MMU-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Mus musculus 60625 R-RNO-964768 https://reactome.org/PathwayBrowser/#/R-RNO-964768 Addition of GlcNAc to the glycan on the A arm IEA Rattus norvegicus 60625 R-RNO-975814 https://reactome.org/PathwayBrowser/#/R-RNO-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Rattus norvegicus 60625 R-SSC-964768 https://reactome.org/PathwayBrowser/#/R-SSC-964768 Addition of GlcNAc to the glycan on the A arm IEA Sus scrofa 60625 R-SSC-975814 https://reactome.org/PathwayBrowser/#/R-SSC-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Sus scrofa 60625 R-XTR-964768 https://reactome.org/PathwayBrowser/#/R-XTR-964768 Addition of GlcNAc to the glycan on the A arm IEA Xenopus tropicalis 60625 R-XTR-975814 https://reactome.org/PathwayBrowser/#/R-XTR-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Xenopus tropicalis 60627 R-BTA-1022127 https://reactome.org/PathwayBrowser/#/R-BTA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Bos taurus 60627 R-BTA-8850594 https://reactome.org/PathwayBrowser/#/R-BTA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Bos taurus 60627 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 60627 R-BTA-964825 https://reactome.org/PathwayBrowser/#/R-BTA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 60627 R-CEL-1022127 https://reactome.org/PathwayBrowser/#/R-CEL-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Caenorhabditis elegans 60627 R-CEL-8850594 https://reactome.org/PathwayBrowser/#/R-CEL-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Caenorhabditis elegans 60627 R-CEL-964825 https://reactome.org/PathwayBrowser/#/R-CEL-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 60627 R-CFA-1022127 https://reactome.org/PathwayBrowser/#/R-CFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Canis familiaris 60627 R-CFA-8850594 https://reactome.org/PathwayBrowser/#/R-CFA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Canis familiaris 60627 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 60627 R-CFA-964825 https://reactome.org/PathwayBrowser/#/R-CFA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 60627 R-DDI-1022127 https://reactome.org/PathwayBrowser/#/R-DDI-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Dictyostelium discoideum 60627 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 60627 R-DDI-964825 https://reactome.org/PathwayBrowser/#/R-DDI-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 60627 R-DME-1022127 https://reactome.org/PathwayBrowser/#/R-DME-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Drosophila melanogaster 60627 R-DME-8850594 https://reactome.org/PathwayBrowser/#/R-DME-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Drosophila melanogaster 60627 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 60627 R-DME-964825 https://reactome.org/PathwayBrowser/#/R-DME-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 60627 R-DRE-1022127 https://reactome.org/PathwayBrowser/#/R-DRE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Danio rerio 60627 R-DRE-8850594 https://reactome.org/PathwayBrowser/#/R-DRE-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Danio rerio 60627 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 60627 R-DRE-964825 https://reactome.org/PathwayBrowser/#/R-DRE-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 60627 R-GGA-1022127 https://reactome.org/PathwayBrowser/#/R-GGA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Gallus gallus 60627 R-GGA-8850594 https://reactome.org/PathwayBrowser/#/R-GGA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Gallus gallus 60627 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 60627 R-GGA-964825 https://reactome.org/PathwayBrowser/#/R-GGA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 60627 R-HSA-1022127 https://reactome.org/PathwayBrowser/#/R-HSA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol TAS Homo sapiens 60627 R-HSA-203973 https://reactome.org/PathwayBrowser/#/R-HSA-203973 Vesicle budding TAS Homo sapiens 60627 R-HSA-204008 https://reactome.org/PathwayBrowser/#/R-HSA-204008 SEC31:SEC13 and v-SNARE recruitment TAS Homo sapiens 60627 R-HSA-5694409 https://reactome.org/PathwayBrowser/#/R-HSA-5694409 Nucleotide exchange on RAB1 TAS Homo sapiens 60627 R-HSA-5694417 https://reactome.org/PathwayBrowser/#/R-HSA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 TAS Homo sapiens 60627 R-HSA-5694418 https://reactome.org/PathwayBrowser/#/R-HSA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 TAS Homo sapiens 60627 R-HSA-5694428 https://reactome.org/PathwayBrowser/#/R-HSA-5694428 LMAN family proteins bind glycosylated cargo TAS Homo sapiens 60627 R-HSA-5694439 https://reactome.org/PathwayBrowser/#/R-HSA-5694439 COPII coat binds TRAPPCII and RAB1:GDP TAS Homo sapiens 60627 R-HSA-5694441 https://reactome.org/PathwayBrowser/#/R-HSA-5694441 CSNK1D phosphorylates SEC23 TAS Homo sapiens 60627 R-HSA-5694446 https://reactome.org/PathwayBrowser/#/R-HSA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle TAS Homo sapiens 60627 R-HSA-5694522 https://reactome.org/PathwayBrowser/#/R-HSA-5694522 Inner coat assembly and cargo binding TAS Homo sapiens 60627 R-HSA-5694527 https://reactome.org/PathwayBrowser/#/R-HSA-5694527 Loss of SAR1B GTPase TAS Homo sapiens 60627 R-HSA-8850594 https://reactome.org/PathwayBrowser/#/R-HSA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins TAS Homo sapiens 60627 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 60627 R-HSA-8867288 https://reactome.org/PathwayBrowser/#/R-HSA-8867288 OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5 TAS Homo sapiens 60627 R-HSA-901024 https://reactome.org/PathwayBrowser/#/R-HSA-901024 MAN1B1 hydrolyses 1,2-linked mannose (a branch) TAS Homo sapiens 60627 R-HSA-901036 https://reactome.org/PathwayBrowser/#/R-HSA-901036 MAN1B1 hydrolyses a second 1,2-linked mannose (a branch) TAS Homo sapiens 60627 R-HSA-9036008 https://reactome.org/PathwayBrowser/#/R-HSA-9036008 Defective MAN1B1 does not hydrolyse a second 1,2-linked mannose (a branch) TAS Homo sapiens 60627 R-HSA-947991 https://reactome.org/PathwayBrowser/#/R-HSA-947991 Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi TAS Homo sapiens 60627 R-HSA-964825 https://reactome.org/PathwayBrowser/#/R-HSA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 60627 R-MMU-1022127 https://reactome.org/PathwayBrowser/#/R-MMU-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Mus musculus 60627 R-MMU-8850594 https://reactome.org/PathwayBrowser/#/R-MMU-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Mus musculus 60627 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 60627 R-MMU-964825 https://reactome.org/PathwayBrowser/#/R-MMU-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 60627 R-PFA-1022127 https://reactome.org/PathwayBrowser/#/R-PFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Plasmodium falciparum 60627 R-RNO-1022127 https://reactome.org/PathwayBrowser/#/R-RNO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Rattus norvegicus 60627 R-RNO-8850594 https://reactome.org/PathwayBrowser/#/R-RNO-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Rattus norvegicus 60627 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 60627 R-RNO-964825 https://reactome.org/PathwayBrowser/#/R-RNO-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 60627 R-SCE-1022127 https://reactome.org/PathwayBrowser/#/R-SCE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Saccharomyces cerevisiae 60627 R-SPO-1022127 https://reactome.org/PathwayBrowser/#/R-SPO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Schizosaccharomyces pombe 60627 R-SSC-1022127 https://reactome.org/PathwayBrowser/#/R-SSC-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Sus scrofa 60627 R-SSC-8850594 https://reactome.org/PathwayBrowser/#/R-SSC-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Sus scrofa 60627 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 60627 R-SSC-964825 https://reactome.org/PathwayBrowser/#/R-SSC-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 60627 R-XTR-1022127 https://reactome.org/PathwayBrowser/#/R-XTR-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Xenopus tropicalis 60627 R-XTR-8850594 https://reactome.org/PathwayBrowser/#/R-XTR-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Xenopus tropicalis 60627 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 60627 R-XTR-964825 https://reactome.org/PathwayBrowser/#/R-XTR-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 60628 R-BTA-1022127 https://reactome.org/PathwayBrowser/#/R-BTA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Bos taurus 60628 R-BTA-8850594 https://reactome.org/PathwayBrowser/#/R-BTA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Bos taurus 60628 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 60628 R-BTA-964825 https://reactome.org/PathwayBrowser/#/R-BTA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 60628 R-CEL-1022127 https://reactome.org/PathwayBrowser/#/R-CEL-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Caenorhabditis elegans 60628 R-CEL-8850594 https://reactome.org/PathwayBrowser/#/R-CEL-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Caenorhabditis elegans 60628 R-CEL-964825 https://reactome.org/PathwayBrowser/#/R-CEL-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 60628 R-CFA-1022127 https://reactome.org/PathwayBrowser/#/R-CFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Canis familiaris 60628 R-CFA-8850594 https://reactome.org/PathwayBrowser/#/R-CFA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Canis familiaris 60628 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 60628 R-CFA-964825 https://reactome.org/PathwayBrowser/#/R-CFA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 60628 R-DDI-1022127 https://reactome.org/PathwayBrowser/#/R-DDI-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Dictyostelium discoideum 60628 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 60628 R-DDI-964825 https://reactome.org/PathwayBrowser/#/R-DDI-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 60628 R-DME-1022127 https://reactome.org/PathwayBrowser/#/R-DME-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Drosophila melanogaster 60628 R-DME-8850594 https://reactome.org/PathwayBrowser/#/R-DME-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Drosophila melanogaster 60628 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 60628 R-DME-964825 https://reactome.org/PathwayBrowser/#/R-DME-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 60628 R-DRE-1022127 https://reactome.org/PathwayBrowser/#/R-DRE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Danio rerio 60628 R-DRE-8850594 https://reactome.org/PathwayBrowser/#/R-DRE-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Danio rerio 60628 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 60628 R-DRE-964825 https://reactome.org/PathwayBrowser/#/R-DRE-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 60628 R-GGA-1022127 https://reactome.org/PathwayBrowser/#/R-GGA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Gallus gallus 60628 R-GGA-8850594 https://reactome.org/PathwayBrowser/#/R-GGA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Gallus gallus 60628 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 60628 R-GGA-964825 https://reactome.org/PathwayBrowser/#/R-GGA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 60628 R-HSA-1022127 https://reactome.org/PathwayBrowser/#/R-HSA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol TAS Homo sapiens 60628 R-HSA-203973 https://reactome.org/PathwayBrowser/#/R-HSA-203973 Vesicle budding TAS Homo sapiens 60628 R-HSA-204008 https://reactome.org/PathwayBrowser/#/R-HSA-204008 SEC31:SEC13 and v-SNARE recruitment TAS Homo sapiens 60628 R-HSA-548884 https://reactome.org/PathwayBrowser/#/R-HSA-548884 UGGT1,2 transfers glucose from DbGP to (un)folded protein:(GlcNAc)2 (Man)8b TAS Homo sapiens 60628 R-HSA-5694409 https://reactome.org/PathwayBrowser/#/R-HSA-5694409 Nucleotide exchange on RAB1 TAS Homo sapiens 60628 R-HSA-5694417 https://reactome.org/PathwayBrowser/#/R-HSA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 TAS Homo sapiens 60628 R-HSA-5694418 https://reactome.org/PathwayBrowser/#/R-HSA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 TAS Homo sapiens 60628 R-HSA-5694428 https://reactome.org/PathwayBrowser/#/R-HSA-5694428 LMAN family proteins bind glycosylated cargo TAS Homo sapiens 60628 R-HSA-5694439 https://reactome.org/PathwayBrowser/#/R-HSA-5694439 COPII coat binds TRAPPCII and RAB1:GDP TAS Homo sapiens 60628 R-HSA-5694441 https://reactome.org/PathwayBrowser/#/R-HSA-5694441 CSNK1D phosphorylates SEC23 TAS Homo sapiens 60628 R-HSA-5694446 https://reactome.org/PathwayBrowser/#/R-HSA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle TAS Homo sapiens 60628 R-HSA-5694522 https://reactome.org/PathwayBrowser/#/R-HSA-5694522 Inner coat assembly and cargo binding TAS Homo sapiens 60628 R-HSA-5694527 https://reactome.org/PathwayBrowser/#/R-HSA-5694527 Loss of SAR1B GTPase TAS Homo sapiens 60628 R-HSA-6782685 https://reactome.org/PathwayBrowser/#/R-HSA-6782685 EDEM1,3 hydrolyse (GlcNAc)2 (Man)8b to (GlcNAc)2 (Man)5 TAS Homo sapiens 60628 R-HSA-8850594 https://reactome.org/PathwayBrowser/#/R-HSA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins TAS Homo sapiens 60628 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 60628 R-HSA-8867288 https://reactome.org/PathwayBrowser/#/R-HSA-8867288 OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5 TAS Homo sapiens 60628 R-HSA-901074 https://reactome.org/PathwayBrowser/#/R-HSA-901074 MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch) TAS Homo sapiens 60628 R-HSA-947991 https://reactome.org/PathwayBrowser/#/R-HSA-947991 Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi TAS Homo sapiens 60628 R-HSA-964825 https://reactome.org/PathwayBrowser/#/R-HSA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 60628 R-MMU-1022127 https://reactome.org/PathwayBrowser/#/R-MMU-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Mus musculus 60628 R-MMU-8850594 https://reactome.org/PathwayBrowser/#/R-MMU-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Mus musculus 60628 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 60628 R-MMU-964825 https://reactome.org/PathwayBrowser/#/R-MMU-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 60628 R-PFA-1022127 https://reactome.org/PathwayBrowser/#/R-PFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Plasmodium falciparum 60628 R-RNO-1022127 https://reactome.org/PathwayBrowser/#/R-RNO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Rattus norvegicus 60628 R-RNO-8850594 https://reactome.org/PathwayBrowser/#/R-RNO-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Rattus norvegicus 60628 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 60628 R-RNO-964825 https://reactome.org/PathwayBrowser/#/R-RNO-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 60628 R-SCE-1022127 https://reactome.org/PathwayBrowser/#/R-SCE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Saccharomyces cerevisiae 60628 R-SPO-1022127 https://reactome.org/PathwayBrowser/#/R-SPO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Schizosaccharomyces pombe 60628 R-SSC-1022127 https://reactome.org/PathwayBrowser/#/R-SSC-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Sus scrofa 60628 R-SSC-8850594 https://reactome.org/PathwayBrowser/#/R-SSC-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Sus scrofa 60628 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 60628 R-SSC-964825 https://reactome.org/PathwayBrowser/#/R-SSC-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 60628 R-XTR-1022127 https://reactome.org/PathwayBrowser/#/R-XTR-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Xenopus tropicalis 60628 R-XTR-8850594 https://reactome.org/PathwayBrowser/#/R-XTR-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Xenopus tropicalis 60628 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 60628 R-XTR-964825 https://reactome.org/PathwayBrowser/#/R-XTR-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 60629 R-BTA-1022127 https://reactome.org/PathwayBrowser/#/R-BTA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Bos taurus 60629 R-BTA-8850594 https://reactome.org/PathwayBrowser/#/R-BTA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Bos taurus 60629 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 60629 R-BTA-964825 https://reactome.org/PathwayBrowser/#/R-BTA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 60629 R-CEL-1022127 https://reactome.org/PathwayBrowser/#/R-CEL-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Caenorhabditis elegans 60629 R-CEL-8850594 https://reactome.org/PathwayBrowser/#/R-CEL-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Caenorhabditis elegans 60629 R-CEL-964825 https://reactome.org/PathwayBrowser/#/R-CEL-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 60629 R-CFA-1022127 https://reactome.org/PathwayBrowser/#/R-CFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Canis familiaris 60629 R-CFA-8850594 https://reactome.org/PathwayBrowser/#/R-CFA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Canis familiaris 60629 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 60629 R-CFA-964825 https://reactome.org/PathwayBrowser/#/R-CFA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 60629 R-DDI-1022127 https://reactome.org/PathwayBrowser/#/R-DDI-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Dictyostelium discoideum 60629 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 60629 R-DDI-964825 https://reactome.org/PathwayBrowser/#/R-DDI-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 60629 R-DME-1022127 https://reactome.org/PathwayBrowser/#/R-DME-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Drosophila melanogaster 60629 R-DME-8850594 https://reactome.org/PathwayBrowser/#/R-DME-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Drosophila melanogaster 60629 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 60629 R-DME-964825 https://reactome.org/PathwayBrowser/#/R-DME-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 60629 R-DRE-1022127 https://reactome.org/PathwayBrowser/#/R-DRE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Danio rerio 60629 R-DRE-8850594 https://reactome.org/PathwayBrowser/#/R-DRE-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Danio rerio 60629 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 60629 R-DRE-964825 https://reactome.org/PathwayBrowser/#/R-DRE-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 60629 R-GGA-1022127 https://reactome.org/PathwayBrowser/#/R-GGA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Gallus gallus 60629 R-GGA-8850594 https://reactome.org/PathwayBrowser/#/R-GGA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Gallus gallus 60629 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 60629 R-GGA-964825 https://reactome.org/PathwayBrowser/#/R-GGA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 60629 R-HSA-1022127 https://reactome.org/PathwayBrowser/#/R-HSA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol TAS Homo sapiens 60629 R-HSA-203973 https://reactome.org/PathwayBrowser/#/R-HSA-203973 Vesicle budding TAS Homo sapiens 60629 R-HSA-204008 https://reactome.org/PathwayBrowser/#/R-HSA-204008 SEC31:SEC13 and v-SNARE recruitment TAS Homo sapiens 60629 R-HSA-5694409 https://reactome.org/PathwayBrowser/#/R-HSA-5694409 Nucleotide exchange on RAB1 TAS Homo sapiens 60629 R-HSA-5694417 https://reactome.org/PathwayBrowser/#/R-HSA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 TAS Homo sapiens 60629 R-HSA-5694418 https://reactome.org/PathwayBrowser/#/R-HSA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 TAS Homo sapiens 60629 R-HSA-5694428 https://reactome.org/PathwayBrowser/#/R-HSA-5694428 LMAN family proteins bind glycosylated cargo TAS Homo sapiens 60629 R-HSA-5694439 https://reactome.org/PathwayBrowser/#/R-HSA-5694439 COPII coat binds TRAPPCII and RAB1:GDP TAS Homo sapiens 60629 R-HSA-5694441 https://reactome.org/PathwayBrowser/#/R-HSA-5694441 CSNK1D phosphorylates SEC23 TAS Homo sapiens 60629 R-HSA-5694446 https://reactome.org/PathwayBrowser/#/R-HSA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle TAS Homo sapiens 60629 R-HSA-5694522 https://reactome.org/PathwayBrowser/#/R-HSA-5694522 Inner coat assembly and cargo binding TAS Homo sapiens 60629 R-HSA-5694527 https://reactome.org/PathwayBrowser/#/R-HSA-5694527 Loss of SAR1B GTPase TAS Homo sapiens 60629 R-HSA-8850594 https://reactome.org/PathwayBrowser/#/R-HSA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins TAS Homo sapiens 60629 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 60629 R-HSA-8867288 https://reactome.org/PathwayBrowser/#/R-HSA-8867288 OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5 TAS Homo sapiens 60629 R-HSA-901039 https://reactome.org/PathwayBrowser/#/R-HSA-901039 MAN1B1 hydrolyses 1,2-linked mannose (c branch) TAS Homo sapiens 60629 R-HSA-947991 https://reactome.org/PathwayBrowser/#/R-HSA-947991 Transport of glycoproteins with Man8 (or Man9) N-glycans to the Golgi TAS Homo sapiens 60629 R-HSA-964825 https://reactome.org/PathwayBrowser/#/R-HSA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 60629 R-MMU-1022127 https://reactome.org/PathwayBrowser/#/R-MMU-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Mus musculus 60629 R-MMU-8850594 https://reactome.org/PathwayBrowser/#/R-MMU-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Mus musculus 60629 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 60629 R-MMU-964825 https://reactome.org/PathwayBrowser/#/R-MMU-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 60629 R-PFA-1022127 https://reactome.org/PathwayBrowser/#/R-PFA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Plasmodium falciparum 60629 R-RNO-1022127 https://reactome.org/PathwayBrowser/#/R-RNO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Rattus norvegicus 60629 R-RNO-8850594 https://reactome.org/PathwayBrowser/#/R-RNO-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Rattus norvegicus 60629 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 60629 R-RNO-964825 https://reactome.org/PathwayBrowser/#/R-RNO-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 60629 R-SCE-1022127 https://reactome.org/PathwayBrowser/#/R-SCE-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Saccharomyces cerevisiae 60629 R-SPO-1022127 https://reactome.org/PathwayBrowser/#/R-SPO-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Schizosaccharomyces pombe 60629 R-SSC-1022127 https://reactome.org/PathwayBrowser/#/R-SSC-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Sus scrofa 60629 R-SSC-8850594 https://reactome.org/PathwayBrowser/#/R-SSC-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Sus scrofa 60629 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 60629 R-SSC-964825 https://reactome.org/PathwayBrowser/#/R-SSC-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 60629 R-XTR-1022127 https://reactome.org/PathwayBrowser/#/R-XTR-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Xenopus tropicalis 60629 R-XTR-8850594 https://reactome.org/PathwayBrowser/#/R-XTR-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Xenopus tropicalis 60629 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 60629 R-XTR-964825 https://reactome.org/PathwayBrowser/#/R-XTR-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 60637 R-BTA-964830 https://reactome.org/PathwayBrowser/#/R-BTA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 60637 R-CEL-964830 https://reactome.org/PathwayBrowser/#/R-CEL-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 60637 R-CFA-964830 https://reactome.org/PathwayBrowser/#/R-CFA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 60637 R-DDI-964830 https://reactome.org/PathwayBrowser/#/R-DDI-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 60637 R-DME-964830 https://reactome.org/PathwayBrowser/#/R-DME-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 60637 R-DRE-964830 https://reactome.org/PathwayBrowser/#/R-DRE-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 60637 R-GGA-964830 https://reactome.org/PathwayBrowser/#/R-GGA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 60637 R-HSA-964830 https://reactome.org/PathwayBrowser/#/R-HSA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 60637 R-MMU-964830 https://reactome.org/PathwayBrowser/#/R-MMU-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 60637 R-RNO-964830 https://reactome.org/PathwayBrowser/#/R-RNO-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 60637 R-SSC-964830 https://reactome.org/PathwayBrowser/#/R-SSC-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 60637 R-XTR-964830 https://reactome.org/PathwayBrowser/#/R-XTR-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 60640 R-HSA-901036 https://reactome.org/PathwayBrowser/#/R-HSA-901036 MAN1B1 hydrolyses a second 1,2-linked mannose (a branch) TAS Homo sapiens 60651 R-BTA-975829 https://reactome.org/PathwayBrowser/#/R-BTA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Bos taurus 60651 R-CEL-975829 https://reactome.org/PathwayBrowser/#/R-CEL-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Caenorhabditis elegans 60651 R-CFA-975829 https://reactome.org/PathwayBrowser/#/R-CFA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Canis familiaris 60651 R-DME-975829 https://reactome.org/PathwayBrowser/#/R-DME-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Drosophila melanogaster 60651 R-DRE-975829 https://reactome.org/PathwayBrowser/#/R-DRE-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Danio rerio 60651 R-GGA-975829 https://reactome.org/PathwayBrowser/#/R-GGA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Gallus gallus 60651 R-HSA-975829 https://reactome.org/PathwayBrowser/#/R-HSA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 TAS Homo sapiens 60651 R-MMU-975829 https://reactome.org/PathwayBrowser/#/R-MMU-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Mus musculus 60651 R-RNO-975829 https://reactome.org/PathwayBrowser/#/R-RNO-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Rattus norvegicus 60651 R-SSC-975829 https://reactome.org/PathwayBrowser/#/R-SSC-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Sus scrofa 60651 R-XTR-975829 https://reactome.org/PathwayBrowser/#/R-XTR-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Xenopus tropicalis 606565 R-BTA-159566 https://reactome.org/PathwayBrowser/#/R-BTA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Bos taurus 606565 R-CEL-159566 https://reactome.org/PathwayBrowser/#/R-CEL-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Caenorhabditis elegans 606565 R-CFA-159566 https://reactome.org/PathwayBrowser/#/R-CFA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Canis familiaris 606565 R-GGA-159566 https://reactome.org/PathwayBrowser/#/R-GGA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Gallus gallus 606565 R-HSA-159566 https://reactome.org/PathwayBrowser/#/R-HSA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A TAS Homo sapiens 606565 R-MMU-159566 https://reactome.org/PathwayBrowser/#/R-MMU-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Mus musculus 606565 R-RNO-159566 https://reactome.org/PathwayBrowser/#/R-RNO-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Rattus norvegicus 606565 R-SSC-159566 https://reactome.org/PathwayBrowser/#/R-SSC-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Sus scrofa 606565 R-XTR-159566 https://reactome.org/PathwayBrowser/#/R-XTR-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Xenopus tropicalis 60721 R-BTA-2162192 https://reactome.org/PathwayBrowser/#/R-BTA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Bos taurus 60721 R-BTA-2162253 https://reactome.org/PathwayBrowser/#/R-BTA-2162253 PDSS1,2 ligates FPP to IPPP IEA Bos taurus 60721 R-CEL-2162192 https://reactome.org/PathwayBrowser/#/R-CEL-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Caenorhabditis elegans 60721 R-CFA-2162192 https://reactome.org/PathwayBrowser/#/R-CFA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Canis familiaris 60721 R-CFA-2162253 https://reactome.org/PathwayBrowser/#/R-CFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Canis familiaris 60721 R-DDI-2162192 https://reactome.org/PathwayBrowser/#/R-DDI-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Dictyostelium discoideum 60721 R-DDI-2162253 https://reactome.org/PathwayBrowser/#/R-DDI-2162253 PDSS1,2 ligates FPP to IPPP IEA Dictyostelium discoideum 60721 R-DME-2162192 https://reactome.org/PathwayBrowser/#/R-DME-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Drosophila melanogaster 60721 R-DME-2162253 https://reactome.org/PathwayBrowser/#/R-DME-2162253 PDSS1,2 ligates FPP to IPPP IEA Drosophila melanogaster 60721 R-DRE-2162192 https://reactome.org/PathwayBrowser/#/R-DRE-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Danio rerio 60721 R-DRE-2162253 https://reactome.org/PathwayBrowser/#/R-DRE-2162253 PDSS1,2 ligates FPP to IPPP IEA Danio rerio 60721 R-GGA-2162192 https://reactome.org/PathwayBrowser/#/R-GGA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Gallus gallus 60721 R-GGA-2162253 https://reactome.org/PathwayBrowser/#/R-GGA-2162253 PDSS1,2 ligates FPP to IPPP IEA Gallus gallus 60721 R-HSA-2162192 https://reactome.org/PathwayBrowser/#/R-HSA-2162192 COQ2 ligates all-E-10PrP2 to PHB TAS Homo sapiens 60721 R-HSA-2162253 https://reactome.org/PathwayBrowser/#/R-HSA-2162253 PDSS1,2 ligates FPP to IPPP TAS Homo sapiens 60721 R-MMU-2162192 https://reactome.org/PathwayBrowser/#/R-MMU-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Mus musculus 60721 R-MMU-2162253 https://reactome.org/PathwayBrowser/#/R-MMU-2162253 PDSS1,2 ligates FPP to IPPP IEA Mus musculus 60721 R-PFA-2162192 https://reactome.org/PathwayBrowser/#/R-PFA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Plasmodium falciparum 60721 R-PFA-2162253 https://reactome.org/PathwayBrowser/#/R-PFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Plasmodium falciparum 60721 R-RNO-2162192 https://reactome.org/PathwayBrowser/#/R-RNO-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Rattus norvegicus 60721 R-RNO-2162253 https://reactome.org/PathwayBrowser/#/R-RNO-2162253 PDSS1,2 ligates FPP to IPPP IEA Rattus norvegicus 60721 R-SCE-2162192 https://reactome.org/PathwayBrowser/#/R-SCE-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Saccharomyces cerevisiae 60721 R-SCE-2162253 https://reactome.org/PathwayBrowser/#/R-SCE-2162253 PDSS1,2 ligates FPP to IPPP IEA Saccharomyces cerevisiae 60721 R-SPO-2162192 https://reactome.org/PathwayBrowser/#/R-SPO-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Schizosaccharomyces pombe 60721 R-SPO-2162253 https://reactome.org/PathwayBrowser/#/R-SPO-2162253 PDSS1,2 ligates FPP to IPPP IEA Schizosaccharomyces pombe 60721 R-SSC-2162192 https://reactome.org/PathwayBrowser/#/R-SSC-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Sus scrofa 60721 R-SSC-2162253 https://reactome.org/PathwayBrowser/#/R-SSC-2162253 PDSS1,2 ligates FPP to IPPP IEA Sus scrofa 60721 R-XTR-2162192 https://reactome.org/PathwayBrowser/#/R-XTR-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Xenopus tropicalis 60721 R-XTR-2162253 https://reactome.org/PathwayBrowser/#/R-XTR-2162253 PDSS1,2 ligates FPP to IPPP IEA Xenopus tropicalis 6073 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 6073 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 6073 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 6073 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 6073 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 6073 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 6073 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 6073 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 6073 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 6073 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 60782 R-BTA-9718020 https://reactome.org/PathwayBrowser/#/R-BTA-9718020 PTGFR binds PTGFR agonists IEA Bos taurus 60782 R-CFA-9718020 https://reactome.org/PathwayBrowser/#/R-CFA-9718020 PTGFR binds PTGFR agonists IEA Canis familiaris 60782 R-DME-9718020 https://reactome.org/PathwayBrowser/#/R-DME-9718020 PTGFR binds PTGFR agonists IEA Drosophila melanogaster 60782 R-DRE-9718020 https://reactome.org/PathwayBrowser/#/R-DRE-9718020 PTGFR binds PTGFR agonists IEA Danio rerio 60782 R-GGA-9718020 https://reactome.org/PathwayBrowser/#/R-GGA-9718020 PTGFR binds PTGFR agonists IEA Gallus gallus 60782 R-HSA-9718020 https://reactome.org/PathwayBrowser/#/R-HSA-9718020 PTGFR binds PTGFR agonists TAS Homo sapiens 60782 R-MMU-9718020 https://reactome.org/PathwayBrowser/#/R-MMU-9718020 PTGFR binds PTGFR agonists IEA Mus musculus 60782 R-RNO-9718020 https://reactome.org/PathwayBrowser/#/R-RNO-9718020 PTGFR binds PTGFR agonists IEA Rattus norvegicus 60782 R-SSC-9718020 https://reactome.org/PathwayBrowser/#/R-SSC-9718020 PTGFR binds PTGFR agonists IEA Sus scrofa 60782 R-XTR-9718020 https://reactome.org/PathwayBrowser/#/R-XTR-9718020 PTGFR binds PTGFR agonists IEA Xenopus tropicalis 60784 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 60784 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 60784 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 60784 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 60784 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 60784 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 60784 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 60784 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 60784 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 60784 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 60784 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 60784 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 60784 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 60784 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 60784 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 60815 R-HSA-1483209 https://reactome.org/PathwayBrowser/#/R-HSA-1483209 PG is converted to BMP TAS Homo sapiens 60872 R-HSA-5662669 https://reactome.org/PathwayBrowser/#/R-HSA-5662669 Dopaquinone transforms to Leucodopachrome (Cyclodopa) TAS Homo sapiens 60872 R-HSA-5672019 https://reactome.org/PathwayBrowser/#/R-HSA-5672019 Leucodopachrome, L-Dopaquinone transform to Dopachrome, L-Dopa TAS Homo sapiens 60913 R-HSA-5244397 https://reactome.org/PathwayBrowser/#/R-HSA-5244397 botB HC:LC binds SYT1 or 2 and GT1b on the target cell surface TAS Homo sapiens 60913 R-HSA-5244402 https://reactome.org/PathwayBrowser/#/R-HSA-5244402 botB:SYT:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 60913 R-HSA-5244404 https://reactome.org/PathwayBrowser/#/R-HSA-5244404 botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 60913 R-HSA-5244415 https://reactome.org/PathwayBrowser/#/R-HSA-5244415 botA HC:LC binds SV2A, B, or C and GT1b on the target cell surface TAS Homo sapiens 60913 R-HSA-5244424 https://reactome.org/PathwayBrowser/#/R-HSA-5244424 botA:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 60913 R-HSA-5244428 https://reactome.org/PathwayBrowser/#/R-HSA-5244428 botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 60913 R-HSA-5244500 https://reactome.org/PathwayBrowser/#/R-HSA-5244500 botE:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 60913 R-HSA-5244503 https://reactome.org/PathwayBrowser/#/R-HSA-5244503 botE HC:LC binds SV2A or B and GT1b on the target cell surface TAS Homo sapiens 60913 R-HSA-5244506 https://reactome.org/PathwayBrowser/#/R-HSA-5244506 botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 60913 R-HSA-5246506 https://reactome.org/PathwayBrowser/#/R-HSA-5246506 botC HC:LC binds GT1b on the target cell surface TAS Homo sapiens 60913 R-HSA-5246509 https://reactome.org/PathwayBrowser/#/R-HSA-5246509 botC:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 60913 R-HSA-5246514 https://reactome.org/PathwayBrowser/#/R-HSA-5246514 botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol TAS Homo sapiens 60913 R-HSA-5250875 https://reactome.org/PathwayBrowser/#/R-HSA-5250875 botF:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 60913 R-HSA-5250880 https://reactome.org/PathwayBrowser/#/R-HSA-5250880 botF HC:LC binds SV2A or B or C and GT1b on the target cell surface TAS Homo sapiens 60913 R-HSA-5250884 https://reactome.org/PathwayBrowser/#/R-HSA-5250884 botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 60913 R-HSA-5250972 https://reactome.org/PathwayBrowser/#/R-HSA-5250972 botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 60913 R-HSA-5250979 https://reactome.org/PathwayBrowser/#/R-HSA-5250979 botG:SYT1:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane TAS Homo sapiens 60913 R-HSA-5250986 https://reactome.org/PathwayBrowser/#/R-HSA-5250986 botG HC:LC binds SYT1 and GT1b on the target cell surface TAS Homo sapiens 60924 R-BTA-9010815 https://reactome.org/PathwayBrowser/#/R-BTA-9010815 SLITs bind keratan sulfate IEA Bos taurus 60924 R-BTA-9014812 https://reactome.org/PathwayBrowser/#/R-BTA-9014812 ROBOs bind keratan sulfate IEA Bos taurus 60924 R-CEL-9010815 https://reactome.org/PathwayBrowser/#/R-CEL-9010815 SLITs bind keratan sulfate IEA Caenorhabditis elegans 60924 R-CEL-9014812 https://reactome.org/PathwayBrowser/#/R-CEL-9014812 ROBOs bind keratan sulfate IEA Caenorhabditis elegans 60924 R-CFA-9010815 https://reactome.org/PathwayBrowser/#/R-CFA-9010815 SLITs bind keratan sulfate IEA Canis familiaris 60924 R-DME-9010815 https://reactome.org/PathwayBrowser/#/R-DME-9010815 SLITs bind keratan sulfate IEA Drosophila melanogaster 60924 R-DME-9014812 https://reactome.org/PathwayBrowser/#/R-DME-9014812 ROBOs bind keratan sulfate IEA Drosophila melanogaster 60924 R-GGA-9010815 https://reactome.org/PathwayBrowser/#/R-GGA-9010815 SLITs bind keratan sulfate IEA Gallus gallus 60924 R-HSA-9010815 https://reactome.org/PathwayBrowser/#/R-HSA-9010815 SLITs bind keratan sulfate TAS Homo sapiens 60924 R-HSA-9014812 https://reactome.org/PathwayBrowser/#/R-HSA-9014812 ROBOs bind keratan sulfate TAS Homo sapiens 60924 R-MMU-9010815 https://reactome.org/PathwayBrowser/#/R-MMU-9010815 SLITs bind keratan sulfate IEA Mus musculus 60924 R-MMU-9014812 https://reactome.org/PathwayBrowser/#/R-MMU-9014812 ROBOs bind keratan sulfate IEA Mus musculus 60924 R-SSC-9010815 https://reactome.org/PathwayBrowser/#/R-SSC-9010815 SLITs bind keratan sulfate IEA Sus scrofa 60943 R-BTA-8932633 https://reactome.org/PathwayBrowser/#/R-BTA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Bos taurus 60943 R-CEL-8932633 https://reactome.org/PathwayBrowser/#/R-CEL-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Caenorhabditis elegans 60943 R-CFA-8932633 https://reactome.org/PathwayBrowser/#/R-CFA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Canis familiaris 60943 R-DRE-8932633 https://reactome.org/PathwayBrowser/#/R-DRE-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Danio rerio 60943 R-GGA-8932633 https://reactome.org/PathwayBrowser/#/R-GGA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Gallus gallus 60943 R-HSA-8932633 https://reactome.org/PathwayBrowser/#/R-HSA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE TAS Homo sapiens 60943 R-MMU-8932633 https://reactome.org/PathwayBrowser/#/R-MMU-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Mus musculus 60943 R-RNO-8932633 https://reactome.org/PathwayBrowser/#/R-RNO-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Rattus norvegicus 60943 R-SSC-8932633 https://reactome.org/PathwayBrowser/#/R-SSC-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Sus scrofa 60943 R-XTR-8932633 https://reactome.org/PathwayBrowser/#/R-XTR-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Xenopus tropicalis 61085 R-BTA-1614645 https://reactome.org/PathwayBrowser/#/R-BTA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Bos taurus 61085 R-BTA-6787757 https://reactome.org/PathwayBrowser/#/R-BTA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Bos taurus 61085 R-BTA-6814165 https://reactome.org/PathwayBrowser/#/R-BTA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Bos taurus 61085 R-CEL-1614645 https://reactome.org/PathwayBrowser/#/R-CEL-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Caenorhabditis elegans 61085 R-CFA-1614645 https://reactome.org/PathwayBrowser/#/R-CFA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Canis familiaris 61085 R-CFA-6787757 https://reactome.org/PathwayBrowser/#/R-CFA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Canis familiaris 61085 R-CFA-6814165 https://reactome.org/PathwayBrowser/#/R-CFA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Canis familiaris 61085 R-DDI-1614645 https://reactome.org/PathwayBrowser/#/R-DDI-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Dictyostelium discoideum 61085 R-DME-1614645 https://reactome.org/PathwayBrowser/#/R-DME-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Drosophila melanogaster 61085 R-DME-6787757 https://reactome.org/PathwayBrowser/#/R-DME-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Drosophila melanogaster 61085 R-DME-6814165 https://reactome.org/PathwayBrowser/#/R-DME-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Drosophila melanogaster 61085 R-DRE-1614645 https://reactome.org/PathwayBrowser/#/R-DRE-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Danio rerio 61085 R-GGA-1614645 https://reactome.org/PathwayBrowser/#/R-GGA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Gallus gallus 61085 R-GGA-6787757 https://reactome.org/PathwayBrowser/#/R-GGA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Gallus gallus 61085 R-GGA-6814165 https://reactome.org/PathwayBrowser/#/R-GGA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Gallus gallus 61085 R-HSA-1614645 https://reactome.org/PathwayBrowser/#/R-HSA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine TAS Homo sapiens 61085 R-HSA-1655443 https://reactome.org/PathwayBrowser/#/R-HSA-1655443 PXKLP-K305-CSAD decarboxylates 3-sulfinoalanine to hypotaurine IEA Homo sapiens 61085 R-HSA-6787757 https://reactome.org/PathwayBrowser/#/R-HSA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs TAS Homo sapiens 61085 R-HSA-6814165 https://reactome.org/PathwayBrowser/#/R-HSA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU TAS Homo sapiens 61085 R-MMU-1614645 https://reactome.org/PathwayBrowser/#/R-MMU-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Mus musculus 61085 R-MMU-6787757 https://reactome.org/PathwayBrowser/#/R-MMU-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Mus musculus 61085 R-MMU-6814165 https://reactome.org/PathwayBrowser/#/R-MMU-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Mus musculus 61085 R-RNO-1614645 https://reactome.org/PathwayBrowser/#/R-RNO-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Rattus norvegicus 61085 R-RNO-1655440 https://reactome.org/PathwayBrowser/#/R-RNO-1655440 PXLP-K305-Csad decarboxylates 3-sulfinoalanine to hypotaurine TAS Rattus norvegicus 61085 R-RNO-6787757 https://reactome.org/PathwayBrowser/#/R-RNO-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Rattus norvegicus 61085 R-RNO-6814165 https://reactome.org/PathwayBrowser/#/R-RNO-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Rattus norvegicus 61085 R-SSC-1614645 https://reactome.org/PathwayBrowser/#/R-SSC-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Sus scrofa 61085 R-SSC-6787757 https://reactome.org/PathwayBrowser/#/R-SSC-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Sus scrofa 61085 R-SSC-6814165 https://reactome.org/PathwayBrowser/#/R-SSC-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Sus scrofa 61085 R-XTR-1614645 https://reactome.org/PathwayBrowser/#/R-XTR-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Xenopus tropicalis 61085 R-XTR-6787757 https://reactome.org/PathwayBrowser/#/R-XTR-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Xenopus tropicalis 61085 R-XTR-6814165 https://reactome.org/PathwayBrowser/#/R-XTR-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Xenopus tropicalis 61088 R-HSA-1222712 https://reactome.org/PathwayBrowser/#/R-HSA-1222712 Nitrosoglutathione gets cleaved to Cys(NO)-Gly TAS Homo sapiens 61120 R-BTA-1008200 https://reactome.org/PathwayBrowser/#/R-BTA-1008200 NFE2 binds the beta globin locus control region IEA Bos taurus 61120 R-BTA-109636 https://reactome.org/PathwayBrowser/#/R-BTA-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Bos taurus 61120 R-BTA-109637 https://reactome.org/PathwayBrowser/#/R-BTA-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Bos taurus 61120 R-BTA-109638 https://reactome.org/PathwayBrowser/#/R-BTA-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Bos taurus 61120 R-BTA-109639 https://reactome.org/PathwayBrowser/#/R-BTA-109639 Formation of the closed pre-initiation complex IEA Bos taurus 61120 R-BTA-109699 https://reactome.org/PathwayBrowser/#/R-BTA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Bos taurus 61120 R-BTA-111264 https://reactome.org/PathwayBrowser/#/R-BTA-111264 Addition of nucleotides between position +11 and +30 IEA Bos taurus 61120 R-BTA-112381 https://reactome.org/PathwayBrowser/#/R-BTA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Bos taurus 61120 R-BTA-112385 https://reactome.org/PathwayBrowser/#/R-BTA-112385 Addition of nucleotides leads to transcript elongation IEA Bos taurus 61120 R-BTA-113430 https://reactome.org/PathwayBrowser/#/R-BTA-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Bos taurus 61120 R-BTA-113503 https://reactome.org/PathwayBrowser/#/R-BTA-113503 PP2A mediated localization of RB1 protein in chromatin IEA Bos taurus 61120 R-BTA-113504 https://reactome.org/PathwayBrowser/#/R-BTA-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Bos taurus 61120 R-BTA-1535903 https://reactome.org/PathwayBrowser/#/R-BTA-1535903 Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements IEA Bos taurus 61120 R-BTA-163296 https://reactome.org/PathwayBrowser/#/R-BTA-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Bos taurus 61120 R-BTA-163310 https://reactome.org/PathwayBrowser/#/R-BTA-163310 TFAM binds to mitochondrial promoters IEA Bos taurus 61120 R-BTA-163320 https://reactome.org/PathwayBrowser/#/R-BTA-163320 Association of mTERF with the termination sequence IEA Bos taurus 61120 R-BTA-1679098 https://reactome.org/PathwayBrowser/#/R-BTA-1679098 Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer IEA Bos taurus 61120 R-BTA-1679589 https://reactome.org/PathwayBrowser/#/R-BTA-1679589 Engulfed CpG DNA binds to endosomal full-length TLR9 IEA Bos taurus 61120 R-BTA-174427 https://reactome.org/PathwayBrowser/#/R-BTA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Bos taurus 61120 R-BTA-174438 https://reactome.org/PathwayBrowser/#/R-BTA-174438 Formation of the Flap Intermediate on the C-strand IEA Bos taurus 61120 R-BTA-174439 https://reactome.org/PathwayBrowser/#/R-BTA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Bos taurus 61120 R-BTA-174441 https://reactome.org/PathwayBrowser/#/R-BTA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Bos taurus 61120 R-BTA-174444 https://reactome.org/PathwayBrowser/#/R-BTA-174444 Formation of C-strand Okazaki fragments IEA Bos taurus 61120 R-BTA-174445 https://reactome.org/PathwayBrowser/#/R-BTA-174445 RPA binds to the Flap on the C-strand IEA Bos taurus 61120 R-BTA-174446 https://reactome.org/PathwayBrowser/#/R-BTA-174446 Removal of remaining Flap from the C-strand IEA Bos taurus 61120 R-BTA-174447 https://reactome.org/PathwayBrowser/#/R-BTA-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Bos taurus 61120 R-BTA-174448 https://reactome.org/PathwayBrowser/#/R-BTA-174448 Formation of Processive Complex on the C-strand of the telomere IEA Bos taurus 61120 R-BTA-174451 https://reactome.org/PathwayBrowser/#/R-BTA-174451 Recruitment of DNA2 endonuclease to the C strand IEA Bos taurus 61120 R-BTA-174452 https://reactome.org/PathwayBrowser/#/R-BTA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Bos taurus 61120 R-BTA-174456 https://reactome.org/PathwayBrowser/#/R-BTA-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Bos taurus 61120 R-BTA-176101 https://reactome.org/PathwayBrowser/#/R-BTA-176101 Recruitment of Rad17-RFC complex to DNA IEA Bos taurus 61120 R-BTA-176175 https://reactome.org/PathwayBrowser/#/R-BTA-176175 Stalling of DNA replication fork and RPA binding IEA Bos taurus 61120 R-BTA-176250 https://reactome.org/PathwayBrowser/#/R-BTA-176250 Binding of ATR-ATRIP to the RPA-ssDNA complex IEA Bos taurus 61120 R-BTA-176264 https://reactome.org/PathwayBrowser/#/R-BTA-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Bos taurus 61120 R-BTA-187895 https://reactome.org/PathwayBrowser/#/R-BTA-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 IEA Bos taurus 61120 R-BTA-188002 https://reactome.org/PathwayBrowser/#/R-BTA-188002 Rab5-mediated recruitment of class III PI3K to TLR9 IEA Bos taurus 61120 R-BTA-3134883 https://reactome.org/PathwayBrowser/#/R-BTA-3134883 Beta-catenin enhances association of IRF3 with CBP/p300 IEA Bos taurus 61120 R-BTA-3134953 https://reactome.org/PathwayBrowser/#/R-BTA-3134953 DHX36 or DHX9 binds MyD88 IEA Bos taurus 61120 R-BTA-3134954 https://reactome.org/PathwayBrowser/#/R-BTA-3134954 DHX9 binds DNA IEA Bos taurus 61120 R-BTA-3134962 https://reactome.org/PathwayBrowser/#/R-BTA-3134962 DHX36 binds DNA IEA Bos taurus 61120 R-BTA-3785711 https://reactome.org/PathwayBrowser/#/R-BTA-3785711 Telomere shortening during replicative exhaustion IEA Bos taurus 61120 R-BTA-3785768 https://reactome.org/PathwayBrowser/#/R-BTA-3785768 MRN complex binds DNA double strand breaks IEA Bos taurus 61120 R-BTA-400143 https://reactome.org/PathwayBrowser/#/R-BTA-400143 Fatty acid ligands activate PPARA IEA Bos taurus 61120 R-BTA-400183 https://reactome.org/PathwayBrowser/#/R-BTA-400183 PPARA:RXRA binds Corepressors of PPARA IEA Bos taurus 61120 R-BTA-400204 https://reactome.org/PathwayBrowser/#/R-BTA-400204 PPARA binds RXRA IEA Bos taurus 61120 R-BTA-5250930 https://reactome.org/PathwayBrowser/#/R-BTA-5250930 B-WICH recruits histone acetyltransferases IEA Bos taurus 61120 R-BTA-5250938 https://reactome.org/PathwayBrowser/#/R-BTA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Bos taurus 61120 R-BTA-5250947 https://reactome.org/PathwayBrowser/#/R-BTA-5250947 B-WICH complex binds rDNA promoter IEA Bos taurus 61120 R-BTA-5682018 https://reactome.org/PathwayBrowser/#/R-BTA-5682018 MRN complex bound to shortened telomeres recruits ATM IEA Bos taurus 61120 R-BTA-5682020 https://reactome.org/PathwayBrowser/#/R-BTA-5682020 MRN complex binds shortened telomeres IEA Bos taurus 61120 R-BTA-5682026 https://reactome.org/PathwayBrowser/#/R-BTA-5682026 MRN bound to shortened telomeres activates ATM IEA Bos taurus 61120 R-BTA-5682044 https://reactome.org/PathwayBrowser/#/R-BTA-5682044 KAT5 acetylates ATM at DNA DSBs IEA Bos taurus 61120 R-BTA-5682586 https://reactome.org/PathwayBrowser/#/R-BTA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Bos taurus 61120 R-BTA-5682588 https://reactome.org/PathwayBrowser/#/R-BTA-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Bos taurus 61120 R-BTA-5682598 https://reactome.org/PathwayBrowser/#/R-BTA-5682598 ATM phosphorylates HERC2 IEA Bos taurus 61120 R-BTA-5682607 https://reactome.org/PathwayBrowser/#/R-BTA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Bos taurus 61120 R-BTA-5682629 https://reactome.org/PathwayBrowser/#/R-BTA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Bos taurus 61120 R-BTA-5682858 https://reactome.org/PathwayBrowser/#/R-BTA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Bos taurus 61120 R-BTA-5682863 https://reactome.org/PathwayBrowser/#/R-BTA-5682863 RNF168 binds DNA DSBs IEA Bos taurus 61120 R-BTA-5682965 https://reactome.org/PathwayBrowser/#/R-BTA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Bos taurus 61120 R-BTA-5682967 https://reactome.org/PathwayBrowser/#/R-BTA-5682967 WHSC1 binds DNA DSBs IEA Bos taurus 61120 R-BTA-5682983 https://reactome.org/PathwayBrowser/#/R-BTA-5682983 ATM phosphorylates WHSC1 IEA Bos taurus 61120 R-BTA-5682992 https://reactome.org/PathwayBrowser/#/R-BTA-5682992 KDM4A,B bind H4K20Me2 IEA Bos taurus 61120 R-BTA-5683077 https://reactome.org/PathwayBrowser/#/R-BTA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Bos taurus 61120 R-BTA-5683384 https://reactome.org/PathwayBrowser/#/R-BTA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Bos taurus 61120 R-BTA-5683385 https://reactome.org/PathwayBrowser/#/R-BTA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Bos taurus 61120 R-BTA-5683405 https://reactome.org/PathwayBrowser/#/R-BTA-5683405 PPP5C dephosphorylates TP53BP1 IEA Bos taurus 61120 R-BTA-5683425 https://reactome.org/PathwayBrowser/#/R-BTA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Bos taurus 61120 R-BTA-5683735 https://reactome.org/PathwayBrowser/#/R-BTA-5683735 CHEK2 is recruited to DNA DSBs IEA Bos taurus 61120 R-BTA-5683801 https://reactome.org/PathwayBrowser/#/R-BTA-5683801 CHEK2 phosphorylates BRCA1 IEA Bos taurus 61120 R-BTA-5683964 https://reactome.org/PathwayBrowser/#/R-BTA-5683964 ATM phosphorylates EYA1-4 IEA Bos taurus 61120 R-BTA-5683967 https://reactome.org/PathwayBrowser/#/R-BTA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Bos taurus 61120 R-BTA-5683986 https://reactome.org/PathwayBrowser/#/R-BTA-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA Bos taurus 61120 R-BTA-5684052 https://reactome.org/PathwayBrowser/#/R-BTA-5684052 PIAS4 SUMOylates MDC1 IEA Bos taurus 61120 R-BTA-5684071 https://reactome.org/PathwayBrowser/#/R-BTA-5684071 RNF4 ubiquitinates MDC1 IEA Bos taurus 61120 R-BTA-5684081 https://reactome.org/PathwayBrowser/#/R-BTA-5684081 MRN complex binds CDK2 and RBBP8 IEA Bos taurus 61120 R-BTA-5684096 https://reactome.org/PathwayBrowser/#/R-BTA-5684096 CDK2 phosphorylates RBBP8 IEA Bos taurus 61120 R-BTA-5684108 https://reactome.org/PathwayBrowser/#/R-BTA-5684108 BRCA1 binds phosphorylated RBBP8 IEA Bos taurus 61120 R-BTA-5684140 https://reactome.org/PathwayBrowser/#/R-BTA-5684140 ATM phosphorylates RBBP8 IEA Bos taurus 61120 R-BTA-5684875 https://reactome.org/PathwayBrowser/#/R-BTA-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Bos taurus 61120 R-BTA-5685011 https://reactome.org/PathwayBrowser/#/R-BTA-5685011 ATR activation at DNA DSBs IEA Bos taurus 61120 R-BTA-5685156 https://reactome.org/PathwayBrowser/#/R-BTA-5685156 ATR phosphorylates RPA2 IEA Bos taurus 61120 R-BTA-5685341 https://reactome.org/PathwayBrowser/#/R-BTA-5685341 BCDX2 complex stabilizes RAD51 filament IEA Bos taurus 61120 R-BTA-5685838 https://reactome.org/PathwayBrowser/#/R-BTA-5685838 CX3 complex binds D-loop structures IEA Bos taurus 61120 R-BTA-5685985 https://reactome.org/PathwayBrowser/#/R-BTA-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Bos taurus 61120 R-BTA-5685994 https://reactome.org/PathwayBrowser/#/R-BTA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Bos taurus 61120 R-BTA-5686440 https://reactome.org/PathwayBrowser/#/R-BTA-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Bos taurus 61120 R-BTA-5686642 https://reactome.org/PathwayBrowser/#/R-BTA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Bos taurus 61120 R-BTA-5686657 https://reactome.org/PathwayBrowser/#/R-BTA-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Bos taurus 61120 R-BTA-5686685 https://reactome.org/PathwayBrowser/#/R-BTA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Bos taurus 61120 R-BTA-5686704 https://reactome.org/PathwayBrowser/#/R-BTA-5686704 Activated ATM phosphorylates DCLRE1C IEA Bos taurus 61120 R-BTA-5686900 https://reactome.org/PathwayBrowser/#/R-BTA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Bos taurus 61120 R-BTA-5686924 https://reactome.org/PathwayBrowser/#/R-BTA-5686924 DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs IEA Bos taurus 61120 R-BTA-5687183 https://reactome.org/PathwayBrowser/#/R-BTA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Bos taurus 61120 R-BTA-5687360 https://reactome.org/PathwayBrowser/#/R-BTA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Bos taurus 61120 R-BTA-5687464 https://reactome.org/PathwayBrowser/#/R-BTA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Bos taurus 61120 R-BTA-5687465 https://reactome.org/PathwayBrowser/#/R-BTA-5687465 MRN complex binds RBBP8 IEA Bos taurus 61120 R-BTA-5687484 https://reactome.org/PathwayBrowser/#/R-BTA-5687484 PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site IEA Bos taurus 61120 R-BTA-5687640 https://reactome.org/PathwayBrowser/#/R-BTA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Bos taurus 61120 R-BTA-5687653 https://reactome.org/PathwayBrowser/#/R-BTA-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Bos taurus 61120 R-BTA-5687664 https://reactome.org/PathwayBrowser/#/R-BTA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Bos taurus 61120 R-BTA-5687673 https://reactome.org/PathwayBrowser/#/R-BTA-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites IEA Bos taurus 61120 R-BTA-5687675 https://reactome.org/PathwayBrowser/#/R-BTA-5687675 LIG3 ligates remaining SSBs in MMEJ IEA Bos taurus 61120 R-BTA-5689317 https://reactome.org/PathwayBrowser/#/R-BTA-5689317 Formation of the pre-incision complex in GG-NER IEA Bos taurus 61120 R-BTA-5689861 https://reactome.org/PathwayBrowser/#/R-BTA-5689861 Recruitment of XPA and release of CAK IEA Bos taurus 61120 R-BTA-5690213 https://reactome.org/PathwayBrowser/#/R-BTA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Bos taurus 61120 R-BTA-5690988 https://reactome.org/PathwayBrowser/#/R-BTA-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Bos taurus 61120 R-BTA-5690990 https://reactome.org/PathwayBrowser/#/R-BTA-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Bos taurus 61120 R-BTA-5690991 https://reactome.org/PathwayBrowser/#/R-BTA-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Bos taurus 61120 R-BTA-5690996 https://reactome.org/PathwayBrowser/#/R-BTA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Bos taurus 61120 R-BTA-5691000 https://reactome.org/PathwayBrowser/#/R-BTA-5691000 TFIIH binds GG-NER site to form a verification complex IEA Bos taurus 61120 R-BTA-5691001 https://reactome.org/PathwayBrowser/#/R-BTA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Bos taurus 61120 R-BTA-5691006 https://reactome.org/PathwayBrowser/#/R-BTA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Bos taurus 61120 R-BTA-5693533 https://reactome.org/PathwayBrowser/#/R-BTA-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends IEA Bos taurus 61120 R-BTA-5693536 https://reactome.org/PathwayBrowser/#/R-BTA-5693536 ATM phosphorylates MDC1 IEA Bos taurus 61120 R-BTA-5693539 https://reactome.org/PathwayBrowser/#/R-BTA-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Bos taurus 61120 R-BTA-5693540 https://reactome.org/PathwayBrowser/#/R-BTA-5693540 MRN activates ATM IEA Bos taurus 61120 R-BTA-5693542 https://reactome.org/PathwayBrowser/#/R-BTA-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Bos taurus 61120 R-BTA-5693549 https://reactome.org/PathwayBrowser/#/R-BTA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Bos taurus 61120 R-BTA-5693551 https://reactome.org/PathwayBrowser/#/R-BTA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Bos taurus 61120 R-BTA-5693564 https://reactome.org/PathwayBrowser/#/R-BTA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Bos taurus 61120 R-BTA-5693566 https://reactome.org/PathwayBrowser/#/R-BTA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Bos taurus 61120 R-BTA-5693574 https://reactome.org/PathwayBrowser/#/R-BTA-5693574 XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ IEA Bos taurus 61120 R-BTA-5693575 https://reactome.org/PathwayBrowser/#/R-BTA-5693575 DNA-PKcs autophosphorylates IEA Bos taurus 61120 R-BTA-5693578 https://reactome.org/PathwayBrowser/#/R-BTA-5693578 TDP1 and TDP2 process unligatable DSB ends IEA Bos taurus 61120 R-BTA-5693580 https://reactome.org/PathwayBrowser/#/R-BTA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Bos taurus 61120 R-BTA-5693583 https://reactome.org/PathwayBrowser/#/R-BTA-5693583 MDC1 associates with gamma-H2AFX at nuclear foci IEA Bos taurus 61120 R-BTA-5693584 https://reactome.org/PathwayBrowser/#/R-BTA-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Bos taurus 61120 R-BTA-5693593 https://reactome.org/PathwayBrowser/#/R-BTA-5693593 D-loop extension by DNA polymerases IEA Bos taurus 61120 R-BTA-5693598 https://reactome.org/PathwayBrowser/#/R-BTA-5693598 ATM phosphorylates NBN IEA Bos taurus 61120 R-BTA-5693599 https://reactome.org/PathwayBrowser/#/R-BTA-5693599 Association of Ku heterodimer with ends of DNA double-strand break IEA Bos taurus 61120 R-BTA-5693602 https://reactome.org/PathwayBrowser/#/R-BTA-5693602 ATM recognizes H2AFX-Nucleosomes IEA Bos taurus 61120 R-BTA-5693608 https://reactome.org/PathwayBrowser/#/R-BTA-5693608 Initial resection of double-strand break ends IEA Bos taurus 61120 R-BTA-5693612 https://reactome.org/PathwayBrowser/#/R-BTA-5693612 MRN complex bound to DNA ends recruits ATM IEA Bos taurus 61120 R-BTA-5693615 https://reactome.org/PathwayBrowser/#/R-BTA-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis IEA Bos taurus 61120 R-BTA-5693620 https://reactome.org/PathwayBrowser/#/R-BTA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Bos taurus 61120 R-BTA-5696655 https://reactome.org/PathwayBrowser/#/R-BTA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Bos taurus 61120 R-BTA-5696664 https://reactome.org/PathwayBrowser/#/R-BTA-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Bos taurus 61120 R-BTA-5696670 https://reactome.org/PathwayBrowser/#/R-BTA-5696670 CHD1L is recruited to GG-NER site IEA Bos taurus 61120 R-BTA-6781818 https://reactome.org/PathwayBrowser/#/R-BTA-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Bos taurus 61120 R-BTA-6781824 https://reactome.org/PathwayBrowser/#/R-BTA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Bos taurus 61120 R-BTA-6781833 https://reactome.org/PathwayBrowser/#/R-BTA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Bos taurus 61120 R-BTA-6781840 https://reactome.org/PathwayBrowser/#/R-BTA-6781840 ERCC6 binds stalled RNA Pol II IEA Bos taurus 61120 R-BTA-6781867 https://reactome.org/PathwayBrowser/#/R-BTA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Bos taurus 61120 R-BTA-6782004 https://reactome.org/PathwayBrowser/#/R-BTA-6782004 Assembly of the pre-incision complex in TC-NER IEA Bos taurus 61120 R-BTA-6782069 https://reactome.org/PathwayBrowser/#/R-BTA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Bos taurus 61120 R-BTA-6782131 https://reactome.org/PathwayBrowser/#/R-BTA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Bos taurus 61120 R-BTA-6782138 https://reactome.org/PathwayBrowser/#/R-BTA-6782138 ERCC5 and RPA bind TC-NER site IEA Bos taurus 61120 R-BTA-6782141 https://reactome.org/PathwayBrowser/#/R-BTA-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Bos taurus 61120 R-BTA-6782204 https://reactome.org/PathwayBrowser/#/R-BTA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Bos taurus 61120 R-BTA-6782208 https://reactome.org/PathwayBrowser/#/R-BTA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Bos taurus 61120 R-BTA-6782211 https://reactome.org/PathwayBrowser/#/R-BTA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Bos taurus 61120 R-BTA-6782224 https://reactome.org/PathwayBrowser/#/R-BTA-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Bos taurus 61120 R-BTA-6782227 https://reactome.org/PathwayBrowser/#/R-BTA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Bos taurus 61120 R-BTA-6782943 https://reactome.org/PathwayBrowser/#/R-BTA-6782943 UV-DDB ubiquitinates XPC IEA Bos taurus 61120 R-BTA-6786166 https://reactome.org/PathwayBrowser/#/R-BTA-6786166 Translesion synthesis across unhooked ICL by POLN IEA Bos taurus 61120 R-BTA-6790454 https://reactome.org/PathwayBrowser/#/R-BTA-6790454 SUMOylation of XPC IEA Bos taurus 61120 R-BTA-6790487 https://reactome.org/PathwayBrowser/#/R-BTA-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Bos taurus 61120 R-BTA-6792712 https://reactome.org/PathwayBrowser/#/R-BTA-6792712 KAT5 acetylates ATM at shortened telomeres IEA Bos taurus 61120 R-BTA-6799332 https://reactome.org/PathwayBrowser/#/R-BTA-6799332 ATR phosphorylates TP53 IEA Bos taurus 61120 R-BTA-68913 https://reactome.org/PathwayBrowser/#/R-BTA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Bos taurus 61120 R-BTA-68914 https://reactome.org/PathwayBrowser/#/R-BTA-68914 DNA polymerase alpha:primase binds at the origin IEA Bos taurus 61120 R-BTA-68944 https://reactome.org/PathwayBrowser/#/R-BTA-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Bos taurus 61120 R-BTA-68950 https://reactome.org/PathwayBrowser/#/R-BTA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Bos taurus 61120 R-BTA-68960 https://reactome.org/PathwayBrowser/#/R-BTA-68960 DNA polymerase epsilon binds at the origin IEA Bos taurus 61120 R-BTA-69053 https://reactome.org/PathwayBrowser/#/R-BTA-69053 RFC binding displaces Pol Alpha IEA Bos taurus 61120 R-BTA-69063 https://reactome.org/PathwayBrowser/#/R-BTA-69063 Loading of PCNA - Sliding Clamp Formation IEA Bos taurus 61120 R-BTA-69068 https://reactome.org/PathwayBrowser/#/R-BTA-69068 RFC dissociates after sliding clamp formation IEA Bos taurus 61120 R-BTA-69074 https://reactome.org/PathwayBrowser/#/R-BTA-69074 Formation of Processive Complex IEA Bos taurus 61120 R-BTA-69116 https://reactome.org/PathwayBrowser/#/R-BTA-69116 Formation of Okazaki fragments IEA Bos taurus 61120 R-BTA-69127 https://reactome.org/PathwayBrowser/#/R-BTA-69127 Formation of the Flap Intermediate IEA Bos taurus 61120 R-BTA-69140 https://reactome.org/PathwayBrowser/#/R-BTA-69140 RPA binds to the Flap IEA Bos taurus 61120 R-BTA-69142 https://reactome.org/PathwayBrowser/#/R-BTA-69142 Recruitment of Dna2 endonuclease IEA Bos taurus 61120 R-BTA-69144 https://reactome.org/PathwayBrowser/#/R-BTA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Bos taurus 61120 R-BTA-69152 https://reactome.org/PathwayBrowser/#/R-BTA-69152 Removal of remaining Flap IEA Bos taurus 61120 R-BTA-69173 https://reactome.org/PathwayBrowser/#/R-BTA-69173 Joining of adjacent Okazaki fragments IEA Bos taurus 61120 R-BTA-69891 https://reactome.org/PathwayBrowser/#/R-BTA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Bos taurus 61120 R-BTA-73718 https://reactome.org/PathwayBrowser/#/R-BTA-73718 UBF-1 Binds rDNA Promoter IEA Bos taurus 61120 R-BTA-73722 https://reactome.org/PathwayBrowser/#/R-BTA-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Bos taurus 61120 R-BTA-73739 https://reactome.org/PathwayBrowser/#/R-BTA-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Bos taurus 61120 R-BTA-73758 https://reactome.org/PathwayBrowser/#/R-BTA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Bos taurus 61120 R-BTA-73769 https://reactome.org/PathwayBrowser/#/R-BTA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Bos taurus 61120 R-BTA-73946 https://reactome.org/PathwayBrowser/#/R-BTA-73946 Abortive initiation after formation of the first phosphodiester bond IEA Bos taurus 61120 R-BTA-75095 https://reactome.org/PathwayBrowser/#/R-BTA-75095 Binding of TFIIE to the growing preinitiation complex IEA Bos taurus 61120 R-BTA-75850 https://reactome.org/PathwayBrowser/#/R-BTA-75850 Addition of the third nucleotide on the nascent transcript IEA Bos taurus 61120 R-BTA-75856 https://reactome.org/PathwayBrowser/#/R-BTA-75856 Abortive Initiation Before Second Transition IEA Bos taurus 61120 R-BTA-75861 https://reactome.org/PathwayBrowser/#/R-BTA-75861 NTP Binds Active Site of RNA Polymerase II IEA Bos taurus 61120 R-BTA-75862 https://reactome.org/PathwayBrowser/#/R-BTA-75862 Fall Back to Closed Pre-initiation Complex IEA Bos taurus 61120 R-BTA-75864 https://reactome.org/PathwayBrowser/#/R-BTA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Bos taurus 61120 R-BTA-75866 https://reactome.org/PathwayBrowser/#/R-BTA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Bos taurus 61120 R-BTA-75869 https://reactome.org/PathwayBrowser/#/R-BTA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Bos taurus 61120 R-BTA-75873 https://reactome.org/PathwayBrowser/#/R-BTA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Bos taurus 61120 R-BTA-75891 https://reactome.org/PathwayBrowser/#/R-BTA-75891 Abortive Initiation After Second Transition IEA Bos taurus 61120 R-BTA-75949 https://reactome.org/PathwayBrowser/#/R-BTA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Bos taurus 61120 R-BTA-76052 https://reactome.org/PathwayBrowser/#/R-BTA-76052 Binding of TFIIIA To type 1 Promoter IEA Bos taurus 61120 R-BTA-76054 https://reactome.org/PathwayBrowser/#/R-BTA-76054 Binding of TFIIIC to TFIIIA:Type I Promoter complex IEA Bos taurus 61120 R-BTA-76056 https://reactome.org/PathwayBrowser/#/R-BTA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Bos taurus 61120 R-BTA-76576 https://reactome.org/PathwayBrowser/#/R-BTA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Bos taurus 61120 R-BTA-77068 https://reactome.org/PathwayBrowser/#/R-BTA-77068 Activation of GT IEA Bos taurus 61120 R-BTA-77069 https://reactome.org/PathwayBrowser/#/R-BTA-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Bos taurus 61120 R-BTA-77071 https://reactome.org/PathwayBrowser/#/R-BTA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Bos taurus 61120 R-BTA-77073 https://reactome.org/PathwayBrowser/#/R-BTA-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Bos taurus 61120 R-BTA-77077 https://reactome.org/PathwayBrowser/#/R-BTA-77077 Capping complex formation IEA Bos taurus 61120 R-BTA-77078 https://reactome.org/PathwayBrowser/#/R-BTA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Bos taurus 61120 R-BTA-77081 https://reactome.org/PathwayBrowser/#/R-BTA-77081 Formation of the CE:GMP intermediate complex IEA Bos taurus 61120 R-BTA-77083 https://reactome.org/PathwayBrowser/#/R-BTA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Bos taurus 61120 R-BTA-77085 https://reactome.org/PathwayBrowser/#/R-BTA-77085 Dissociation of transcript with 5'-GMP from GT IEA Bos taurus 61120 R-BTA-77090 https://reactome.org/PathwayBrowser/#/R-BTA-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Bos taurus 61120 R-BTA-83723 https://reactome.org/PathwayBrowser/#/R-BTA-83723 Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex IEA Bos taurus 61120 R-BTA-83788 https://reactome.org/PathwayBrowser/#/R-BTA-83788 Binding of TFIIIC to Type 2 promoter IEA Bos taurus 61120 R-BTA-83790 https://reactome.org/PathwayBrowser/#/R-BTA-83790 Binding of TFIIIB to TFIIC: Type 2 Promoter Complex IEA Bos taurus 61120 R-BTA-83791 https://reactome.org/PathwayBrowser/#/R-BTA-83791 Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter IEA Bos taurus 61120 R-BTA-83793 https://reactome.org/PathwayBrowser/#/R-BTA-83793 Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex IEA Bos taurus 61120 R-BTA-83803 https://reactome.org/PathwayBrowser/#/R-BTA-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Bos taurus 61120 R-BTA-83805 https://reactome.org/PathwayBrowser/#/R-BTA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Bos taurus 61120 R-BTA-9604480 https://reactome.org/PathwayBrowser/#/R-BTA-9604480 NFkB complex translocates from the cytosol to the nucleus IEA Bos taurus 61120 R-BTA-9604487 https://reactome.org/PathwayBrowser/#/R-BTA-9604487 p-IRF7:p-IRF7 translocates to the nucleus IEA Bos taurus 61120 R-BTA-9613494 https://reactome.org/PathwayBrowser/#/R-BTA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Bos taurus 61120 R-BTA-9613497 https://reactome.org/PathwayBrowser/#/R-BTA-9613497 Unwinding DNA for the nascent transcript IEA Bos taurus 61120 R-BTA-9684118 https://reactome.org/PathwayBrowser/#/R-BTA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Bos taurus 61120 R-BTA-9734475 https://reactome.org/PathwayBrowser/#/R-BTA-9734475 PPARA binds fibrates IEA Bos taurus 61120 R-BTA-996727 https://reactome.org/PathwayBrowser/#/R-BTA-996727 REST recruits the BHC complex IEA Bos taurus 61120 R-CEL-109636 https://reactome.org/PathwayBrowser/#/R-CEL-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Caenorhabditis elegans 61120 R-CEL-109637 https://reactome.org/PathwayBrowser/#/R-CEL-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Caenorhabditis elegans 61120 R-CEL-109638 https://reactome.org/PathwayBrowser/#/R-CEL-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Caenorhabditis elegans 61120 R-CEL-109639 https://reactome.org/PathwayBrowser/#/R-CEL-109639 Formation of the closed pre-initiation complex IEA Caenorhabditis elegans 61120 R-CEL-111264 https://reactome.org/PathwayBrowser/#/R-CEL-111264 Addition of nucleotides between position +11 and +30 IEA Caenorhabditis elegans 61120 R-CEL-112379 https://reactome.org/PathwayBrowser/#/R-CEL-112379 Recruitment of elongation factors to form elongation complex IEA Caenorhabditis elegans 61120 R-CEL-112385 https://reactome.org/PathwayBrowser/#/R-CEL-112385 Addition of nucleotides leads to transcript elongation IEA Caenorhabditis elegans 61120 R-CEL-113430 https://reactome.org/PathwayBrowser/#/R-CEL-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Caenorhabditis elegans 61120 R-CEL-113504 https://reactome.org/PathwayBrowser/#/R-CEL-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Caenorhabditis elegans 61120 R-CEL-1535903 https://reactome.org/PathwayBrowser/#/R-CEL-1535903 Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements IEA Caenorhabditis elegans 61120 R-CEL-163310 https://reactome.org/PathwayBrowser/#/R-CEL-163310 TFAM binds to mitochondrial promoters IEA Caenorhabditis elegans 61120 R-CEL-176264 https://reactome.org/PathwayBrowser/#/R-CEL-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Caenorhabditis elegans 61120 R-CEL-3134954 https://reactome.org/PathwayBrowser/#/R-CEL-3134954 DHX9 binds DNA IEA Caenorhabditis elegans 61120 R-CEL-400204 https://reactome.org/PathwayBrowser/#/R-CEL-400204 PPARA binds RXRA IEA Caenorhabditis elegans 61120 R-CEL-5250938 https://reactome.org/PathwayBrowser/#/R-CEL-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Caenorhabditis elegans 61120 R-CEL-5685156 https://reactome.org/PathwayBrowser/#/R-CEL-5685156 ATR phosphorylates RPA2 IEA Caenorhabditis elegans 61120 R-CEL-5687464 https://reactome.org/PathwayBrowser/#/R-CEL-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Caenorhabditis elegans 61120 R-CEL-5687664 https://reactome.org/PathwayBrowser/#/R-CEL-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Caenorhabditis elegans 61120 R-CEL-5690213 https://reactome.org/PathwayBrowser/#/R-CEL-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Caenorhabditis elegans 61120 R-CEL-5690990 https://reactome.org/PathwayBrowser/#/R-CEL-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Caenorhabditis elegans 61120 R-CEL-5690996 https://reactome.org/PathwayBrowser/#/R-CEL-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Caenorhabditis elegans 61120 R-CEL-5691000 https://reactome.org/PathwayBrowser/#/R-CEL-5691000 TFIIH binds GG-NER site to form a verification complex IEA Caenorhabditis elegans 61120 R-CEL-5691001 https://reactome.org/PathwayBrowser/#/R-CEL-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Caenorhabditis elegans 61120 R-CEL-5691006 https://reactome.org/PathwayBrowser/#/R-CEL-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Caenorhabditis elegans 61120 R-CEL-5696655 https://reactome.org/PathwayBrowser/#/R-CEL-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Caenorhabditis elegans 61120 R-CEL-6781818 https://reactome.org/PathwayBrowser/#/R-CEL-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Caenorhabditis elegans 61120 R-CEL-6781824 https://reactome.org/PathwayBrowser/#/R-CEL-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Caenorhabditis elegans 61120 R-CEL-6781833 https://reactome.org/PathwayBrowser/#/R-CEL-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Caenorhabditis elegans 61120 R-CEL-6781840 https://reactome.org/PathwayBrowser/#/R-CEL-6781840 ERCC6 binds stalled RNA Pol II IEA Caenorhabditis elegans 61120 R-CEL-6781867 https://reactome.org/PathwayBrowser/#/R-CEL-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Caenorhabditis elegans 61120 R-CEL-6782004 https://reactome.org/PathwayBrowser/#/R-CEL-6782004 Assembly of the pre-incision complex in TC-NER IEA Caenorhabditis elegans 61120 R-CEL-6782069 https://reactome.org/PathwayBrowser/#/R-CEL-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Caenorhabditis elegans 61120 R-CEL-6782131 https://reactome.org/PathwayBrowser/#/R-CEL-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Caenorhabditis elegans 61120 R-CEL-6782141 https://reactome.org/PathwayBrowser/#/R-CEL-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Caenorhabditis elegans 61120 R-CEL-6782204 https://reactome.org/PathwayBrowser/#/R-CEL-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Caenorhabditis elegans 61120 R-CEL-6782208 https://reactome.org/PathwayBrowser/#/R-CEL-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Caenorhabditis elegans 61120 R-CEL-6782211 https://reactome.org/PathwayBrowser/#/R-CEL-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Caenorhabditis elegans 61120 R-CEL-6782227 https://reactome.org/PathwayBrowser/#/R-CEL-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Caenorhabditis elegans 61120 R-CEL-6782943 https://reactome.org/PathwayBrowser/#/R-CEL-6782943 UV-DDB ubiquitinates XPC IEA Caenorhabditis elegans 61120 R-CEL-6790454 https://reactome.org/PathwayBrowser/#/R-CEL-6790454 SUMOylation of XPC IEA Caenorhabditis elegans 61120 R-CEL-68913 https://reactome.org/PathwayBrowser/#/R-CEL-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Caenorhabditis elegans 61120 R-CEL-68914 https://reactome.org/PathwayBrowser/#/R-CEL-68914 DNA polymerase alpha:primase binds at the origin IEA Caenorhabditis elegans 61120 R-CEL-68944 https://reactome.org/PathwayBrowser/#/R-CEL-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Caenorhabditis elegans 61120 R-CEL-68950 https://reactome.org/PathwayBrowser/#/R-CEL-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Caenorhabditis elegans 61120 R-CEL-68960 https://reactome.org/PathwayBrowser/#/R-CEL-68960 DNA polymerase epsilon binds at the origin IEA Caenorhabditis elegans 61120 R-CEL-69053 https://reactome.org/PathwayBrowser/#/R-CEL-69053 RFC binding displaces Pol Alpha IEA Caenorhabditis elegans 61120 R-CEL-69063 https://reactome.org/PathwayBrowser/#/R-CEL-69063 Loading of PCNA - Sliding Clamp Formation IEA Caenorhabditis elegans 61120 R-CEL-69068 https://reactome.org/PathwayBrowser/#/R-CEL-69068 RFC dissociates after sliding clamp formation IEA Caenorhabditis elegans 61120 R-CEL-69074 https://reactome.org/PathwayBrowser/#/R-CEL-69074 Formation of Processive Complex IEA Caenorhabditis elegans 61120 R-CEL-69116 https://reactome.org/PathwayBrowser/#/R-CEL-69116 Formation of Okazaki fragments IEA Caenorhabditis elegans 61120 R-CEL-69127 https://reactome.org/PathwayBrowser/#/R-CEL-69127 Formation of the Flap Intermediate IEA Caenorhabditis elegans 61120 R-CEL-69142 https://reactome.org/PathwayBrowser/#/R-CEL-69142 Recruitment of Dna2 endonuclease IEA Caenorhabditis elegans 61120 R-CEL-69152 https://reactome.org/PathwayBrowser/#/R-CEL-69152 Removal of remaining Flap IEA Caenorhabditis elegans 61120 R-CEL-69173 https://reactome.org/PathwayBrowser/#/R-CEL-69173 Joining of adjacent Okazaki fragments IEA Caenorhabditis elegans 61120 R-CEL-73769 https://reactome.org/PathwayBrowser/#/R-CEL-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Caenorhabditis elegans 61120 R-CEL-73946 https://reactome.org/PathwayBrowser/#/R-CEL-73946 Abortive initiation after formation of the first phosphodiester bond IEA Caenorhabditis elegans 61120 R-CEL-75095 https://reactome.org/PathwayBrowser/#/R-CEL-75095 Binding of TFIIE to the growing preinitiation complex IEA Caenorhabditis elegans 61120 R-CEL-75850 https://reactome.org/PathwayBrowser/#/R-CEL-75850 Addition of the third nucleotide on the nascent transcript IEA Caenorhabditis elegans 61120 R-CEL-75856 https://reactome.org/PathwayBrowser/#/R-CEL-75856 Abortive Initiation Before Second Transition IEA Caenorhabditis elegans 61120 R-CEL-75861 https://reactome.org/PathwayBrowser/#/R-CEL-75861 NTP Binds Active Site of RNA Polymerase II IEA Caenorhabditis elegans 61120 R-CEL-75862 https://reactome.org/PathwayBrowser/#/R-CEL-75862 Fall Back to Closed Pre-initiation Complex IEA Caenorhabditis elegans 61120 R-CEL-75864 https://reactome.org/PathwayBrowser/#/R-CEL-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Caenorhabditis elegans 61120 R-CEL-75866 https://reactome.org/PathwayBrowser/#/R-CEL-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Caenorhabditis elegans 61120 R-CEL-75869 https://reactome.org/PathwayBrowser/#/R-CEL-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Caenorhabditis elegans 61120 R-CEL-75873 https://reactome.org/PathwayBrowser/#/R-CEL-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Caenorhabditis elegans 61120 R-CEL-75891 https://reactome.org/PathwayBrowser/#/R-CEL-75891 Abortive Initiation After Second Transition IEA Caenorhabditis elegans 61120 R-CEL-75949 https://reactome.org/PathwayBrowser/#/R-CEL-75949 RNA Polymerase II Promoter Opening: First Transition IEA Caenorhabditis elegans 61120 R-CEL-76576 https://reactome.org/PathwayBrowser/#/R-CEL-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Caenorhabditis elegans 61120 R-CEL-77068 https://reactome.org/PathwayBrowser/#/R-CEL-77068 Activation of GT IEA Caenorhabditis elegans 61120 R-CEL-77069 https://reactome.org/PathwayBrowser/#/R-CEL-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Caenorhabditis elegans 61120 R-CEL-77071 https://reactome.org/PathwayBrowser/#/R-CEL-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Caenorhabditis elegans 61120 R-CEL-77073 https://reactome.org/PathwayBrowser/#/R-CEL-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Caenorhabditis elegans 61120 R-CEL-77077 https://reactome.org/PathwayBrowser/#/R-CEL-77077 Capping complex formation IEA Caenorhabditis elegans 61120 R-CEL-77078 https://reactome.org/PathwayBrowser/#/R-CEL-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Caenorhabditis elegans 61120 R-CEL-77081 https://reactome.org/PathwayBrowser/#/R-CEL-77081 Formation of the CE:GMP intermediate complex IEA Caenorhabditis elegans 61120 R-CEL-77083 https://reactome.org/PathwayBrowser/#/R-CEL-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Caenorhabditis elegans 61120 R-CEL-77085 https://reactome.org/PathwayBrowser/#/R-CEL-77085 Dissociation of transcript with 5'-GMP from GT IEA Caenorhabditis elegans 61120 R-CEL-77090 https://reactome.org/PathwayBrowser/#/R-CEL-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Caenorhabditis elegans 61120 R-CEL-9613494 https://reactome.org/PathwayBrowser/#/R-CEL-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Caenorhabditis elegans 61120 R-CEL-9613497 https://reactome.org/PathwayBrowser/#/R-CEL-9613497 Unwinding DNA for the nascent transcript IEA Caenorhabditis elegans 61120 R-CEL-9684118 https://reactome.org/PathwayBrowser/#/R-CEL-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Caenorhabditis elegans 61120 R-CFA-1008200 https://reactome.org/PathwayBrowser/#/R-CFA-1008200 NFE2 binds the beta globin locus control region IEA Canis familiaris 61120 R-CFA-109636 https://reactome.org/PathwayBrowser/#/R-CFA-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Canis familiaris 61120 R-CFA-109637 https://reactome.org/PathwayBrowser/#/R-CFA-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Canis familiaris 61120 R-CFA-109638 https://reactome.org/PathwayBrowser/#/R-CFA-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Canis familiaris 61120 R-CFA-109639 https://reactome.org/PathwayBrowser/#/R-CFA-109639 Formation of the closed pre-initiation complex IEA Canis familiaris 61120 R-CFA-109699 https://reactome.org/PathwayBrowser/#/R-CFA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Canis familiaris 61120 R-CFA-111264 https://reactome.org/PathwayBrowser/#/R-CFA-111264 Addition of nucleotides between position +11 and +30 IEA Canis familiaris 61120 R-CFA-112379 https://reactome.org/PathwayBrowser/#/R-CFA-112379 Recruitment of elongation factors to form elongation complex IEA Canis familiaris 61120 R-CFA-112381 https://reactome.org/PathwayBrowser/#/R-CFA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Canis familiaris 61120 R-CFA-112385 https://reactome.org/PathwayBrowser/#/R-CFA-112385 Addition of nucleotides leads to transcript elongation IEA Canis familiaris 61120 R-CFA-113429 https://reactome.org/PathwayBrowser/#/R-CFA-113429 Elongating transcript encounters a lesion in the template IEA Canis familiaris 61120 R-CFA-113430 https://reactome.org/PathwayBrowser/#/R-CFA-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Canis familiaris 61120 R-CFA-113503 https://reactome.org/PathwayBrowser/#/R-CFA-113503 PP2A mediated localization of RB1 protein in chromatin IEA Canis familiaris 61120 R-CFA-113504 https://reactome.org/PathwayBrowser/#/R-CFA-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Canis familiaris 61120 R-CFA-1535903 https://reactome.org/PathwayBrowser/#/R-CFA-1535903 Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements IEA Canis familiaris 61120 R-CFA-163296 https://reactome.org/PathwayBrowser/#/R-CFA-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Canis familiaris 61120 R-CFA-163310 https://reactome.org/PathwayBrowser/#/R-CFA-163310 TFAM binds to mitochondrial promoters IEA Canis familiaris 61120 R-CFA-163320 https://reactome.org/PathwayBrowser/#/R-CFA-163320 Association of mTERF with the termination sequence IEA Canis familiaris 61120 R-CFA-1679098 https://reactome.org/PathwayBrowser/#/R-CFA-1679098 Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer IEA Canis familiaris 61120 R-CFA-1679589 https://reactome.org/PathwayBrowser/#/R-CFA-1679589 Engulfed CpG DNA binds to endosomal full-length TLR9 IEA Canis familiaris 61120 R-CFA-174427 https://reactome.org/PathwayBrowser/#/R-CFA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Canis familiaris 61120 R-CFA-174438 https://reactome.org/PathwayBrowser/#/R-CFA-174438 Formation of the Flap Intermediate on the C-strand IEA Canis familiaris 61120 R-CFA-174439 https://reactome.org/PathwayBrowser/#/R-CFA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Canis familiaris 61120 R-CFA-174441 https://reactome.org/PathwayBrowser/#/R-CFA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Canis familiaris 61120 R-CFA-174444 https://reactome.org/PathwayBrowser/#/R-CFA-174444 Formation of C-strand Okazaki fragments IEA Canis familiaris 61120 R-CFA-174445 https://reactome.org/PathwayBrowser/#/R-CFA-174445 RPA binds to the Flap on the C-strand IEA Canis familiaris 61120 R-CFA-174446 https://reactome.org/PathwayBrowser/#/R-CFA-174446 Removal of remaining Flap from the C-strand IEA Canis familiaris 61120 R-CFA-174447 https://reactome.org/PathwayBrowser/#/R-CFA-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Canis familiaris 61120 R-CFA-174448 https://reactome.org/PathwayBrowser/#/R-CFA-174448 Formation of Processive Complex on the C-strand of the telomere IEA Canis familiaris 61120 R-CFA-174451 https://reactome.org/PathwayBrowser/#/R-CFA-174451 Recruitment of DNA2 endonuclease to the C strand IEA Canis familiaris 61120 R-CFA-174452 https://reactome.org/PathwayBrowser/#/R-CFA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Canis familiaris 61120 R-CFA-174456 https://reactome.org/PathwayBrowser/#/R-CFA-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Canis familiaris 61120 R-CFA-176101 https://reactome.org/PathwayBrowser/#/R-CFA-176101 Recruitment of Rad17-RFC complex to DNA IEA Canis familiaris 61120 R-CFA-176175 https://reactome.org/PathwayBrowser/#/R-CFA-176175 Stalling of DNA replication fork and RPA binding IEA Canis familiaris 61120 R-CFA-176250 https://reactome.org/PathwayBrowser/#/R-CFA-176250 Binding of ATR-ATRIP to the RPA-ssDNA complex IEA Canis familiaris 61120 R-CFA-176264 https://reactome.org/PathwayBrowser/#/R-CFA-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Canis familiaris 61120 R-CFA-187895 https://reactome.org/PathwayBrowser/#/R-CFA-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 IEA Canis familiaris 61120 R-CFA-188002 https://reactome.org/PathwayBrowser/#/R-CFA-188002 Rab5-mediated recruitment of class III PI3K to TLR9 IEA Canis familiaris 61120 R-CFA-211247 https://reactome.org/PathwayBrowser/#/R-CFA-211247 Cleavage of DNA by DFF40 IEA Canis familiaris 61120 R-CFA-2247510 https://reactome.org/PathwayBrowser/#/R-CFA-2247510 MARCO:ligand is endocytosed IEA Canis familiaris 61120 R-CFA-3134883 https://reactome.org/PathwayBrowser/#/R-CFA-3134883 Beta-catenin enhances association of IRF3 with CBP/p300 IEA Canis familiaris 61120 R-CFA-3134953 https://reactome.org/PathwayBrowser/#/R-CFA-3134953 DHX36 or DHX9 binds MyD88 IEA Canis familiaris 61120 R-CFA-3134954 https://reactome.org/PathwayBrowser/#/R-CFA-3134954 DHX9 binds DNA IEA Canis familiaris 61120 R-CFA-3134962 https://reactome.org/PathwayBrowser/#/R-CFA-3134962 DHX36 binds DNA IEA Canis familiaris 61120 R-CFA-3785711 https://reactome.org/PathwayBrowser/#/R-CFA-3785711 Telomere shortening during replicative exhaustion IEA Canis familiaris 61120 R-CFA-3785768 https://reactome.org/PathwayBrowser/#/R-CFA-3785768 MRN complex binds DNA double strand breaks IEA Canis familiaris 61120 R-CFA-400143 https://reactome.org/PathwayBrowser/#/R-CFA-400143 Fatty acid ligands activate PPARA IEA Canis familiaris 61120 R-CFA-400183 https://reactome.org/PathwayBrowser/#/R-CFA-400183 PPARA:RXRA binds Corepressors of PPARA IEA Canis familiaris 61120 R-CFA-400204 https://reactome.org/PathwayBrowser/#/R-CFA-400204 PPARA binds RXRA IEA Canis familiaris 61120 R-CFA-5250930 https://reactome.org/PathwayBrowser/#/R-CFA-5250930 B-WICH recruits histone acetyltransferases IEA Canis familiaris 61120 R-CFA-5250938 https://reactome.org/PathwayBrowser/#/R-CFA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Canis familiaris 61120 R-CFA-5250947 https://reactome.org/PathwayBrowser/#/R-CFA-5250947 B-WICH complex binds rDNA promoter IEA Canis familiaris 61120 R-CFA-5682018 https://reactome.org/PathwayBrowser/#/R-CFA-5682018 MRN complex bound to shortened telomeres recruits ATM IEA Canis familiaris 61120 R-CFA-5682020 https://reactome.org/PathwayBrowser/#/R-CFA-5682020 MRN complex binds shortened telomeres IEA Canis familiaris 61120 R-CFA-5682026 https://reactome.org/PathwayBrowser/#/R-CFA-5682026 MRN bound to shortened telomeres activates ATM IEA Canis familiaris 61120 R-CFA-5682044 https://reactome.org/PathwayBrowser/#/R-CFA-5682044 KAT5 acetylates ATM at DNA DSBs IEA Canis familiaris 61120 R-CFA-5682586 https://reactome.org/PathwayBrowser/#/R-CFA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Canis familiaris 61120 R-CFA-5682598 https://reactome.org/PathwayBrowser/#/R-CFA-5682598 ATM phosphorylates HERC2 IEA Canis familiaris 61120 R-CFA-5682629 https://reactome.org/PathwayBrowser/#/R-CFA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Canis familiaris 61120 R-CFA-5682858 https://reactome.org/PathwayBrowser/#/R-CFA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Canis familiaris 61120 R-CFA-5682863 https://reactome.org/PathwayBrowser/#/R-CFA-5682863 RNF168 binds DNA DSBs IEA Canis familiaris 61120 R-CFA-5682965 https://reactome.org/PathwayBrowser/#/R-CFA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Canis familiaris 61120 R-CFA-5682967 https://reactome.org/PathwayBrowser/#/R-CFA-5682967 WHSC1 binds DNA DSBs IEA Canis familiaris 61120 R-CFA-5682983 https://reactome.org/PathwayBrowser/#/R-CFA-5682983 ATM phosphorylates WHSC1 IEA Canis familiaris 61120 R-CFA-5682992 https://reactome.org/PathwayBrowser/#/R-CFA-5682992 KDM4A,B bind H4K20Me2 IEA Canis familiaris 61120 R-CFA-5683077 https://reactome.org/PathwayBrowser/#/R-CFA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Canis familiaris 61120 R-CFA-5683384 https://reactome.org/PathwayBrowser/#/R-CFA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Canis familiaris 61120 R-CFA-5683385 https://reactome.org/PathwayBrowser/#/R-CFA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Canis familiaris 61120 R-CFA-5683405 https://reactome.org/PathwayBrowser/#/R-CFA-5683405 PPP5C dephosphorylates TP53BP1 IEA Canis familiaris 61120 R-CFA-5683425 https://reactome.org/PathwayBrowser/#/R-CFA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Canis familiaris 61120 R-CFA-5683735 https://reactome.org/PathwayBrowser/#/R-CFA-5683735 CHEK2 is recruited to DNA DSBs IEA Canis familiaris 61120 R-CFA-5683801 https://reactome.org/PathwayBrowser/#/R-CFA-5683801 CHEK2 phosphorylates BRCA1 IEA Canis familiaris 61120 R-CFA-5683964 https://reactome.org/PathwayBrowser/#/R-CFA-5683964 ATM phosphorylates EYA1-4 IEA Canis familiaris 61120 R-CFA-5683967 https://reactome.org/PathwayBrowser/#/R-CFA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Canis familiaris 61120 R-CFA-5683986 https://reactome.org/PathwayBrowser/#/R-CFA-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA Canis familiaris 61120 R-CFA-5684081 https://reactome.org/PathwayBrowser/#/R-CFA-5684081 MRN complex binds CDK2 and RBBP8 IEA Canis familiaris 61120 R-CFA-5684096 https://reactome.org/PathwayBrowser/#/R-CFA-5684096 CDK2 phosphorylates RBBP8 IEA Canis familiaris 61120 R-CFA-5684108 https://reactome.org/PathwayBrowser/#/R-CFA-5684108 BRCA1 binds phosphorylated RBBP8 IEA Canis familiaris 61120 R-CFA-5684140 https://reactome.org/PathwayBrowser/#/R-CFA-5684140 ATM phosphorylates RBBP8 IEA Canis familiaris 61120 R-CFA-5684875 https://reactome.org/PathwayBrowser/#/R-CFA-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Canis familiaris 61120 R-CFA-5684882 https://reactome.org/PathwayBrowser/#/R-CFA-5684882 CHEK1 is recruited to resected DNA DSBs IEA Canis familiaris 61120 R-CFA-5684887 https://reactome.org/PathwayBrowser/#/R-CFA-5684887 Activation of CHEK1 at resected DNA DSBs IEA Canis familiaris 61120 R-CFA-5685011 https://reactome.org/PathwayBrowser/#/R-CFA-5685011 ATR activation at DNA DSBs IEA Canis familiaris 61120 R-CFA-5685156 https://reactome.org/PathwayBrowser/#/R-CFA-5685156 ATR phosphorylates RPA2 IEA Canis familiaris 61120 R-CFA-5685341 https://reactome.org/PathwayBrowser/#/R-CFA-5685341 BCDX2 complex stabilizes RAD51 filament IEA Canis familiaris 61120 R-CFA-5685838 https://reactome.org/PathwayBrowser/#/R-CFA-5685838 CX3 complex binds D-loop structures IEA Canis familiaris 61120 R-CFA-5685985 https://reactome.org/PathwayBrowser/#/R-CFA-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Canis familiaris 61120 R-CFA-5685994 https://reactome.org/PathwayBrowser/#/R-CFA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Canis familiaris 61120 R-CFA-5686440 https://reactome.org/PathwayBrowser/#/R-CFA-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Canis familiaris 61120 R-CFA-5686642 https://reactome.org/PathwayBrowser/#/R-CFA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Canis familiaris 61120 R-CFA-5686657 https://reactome.org/PathwayBrowser/#/R-CFA-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Canis familiaris 61120 R-CFA-5686685 https://reactome.org/PathwayBrowser/#/R-CFA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Canis familiaris 61120 R-CFA-5686704 https://reactome.org/PathwayBrowser/#/R-CFA-5686704 Activated ATM phosphorylates DCLRE1C IEA Canis familiaris 61120 R-CFA-5686900 https://reactome.org/PathwayBrowser/#/R-CFA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Canis familiaris 61120 R-CFA-5686924 https://reactome.org/PathwayBrowser/#/R-CFA-5686924 DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs IEA Canis familiaris 61120 R-CFA-5687183 https://reactome.org/PathwayBrowser/#/R-CFA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Canis familiaris 61120 R-CFA-5687360 https://reactome.org/PathwayBrowser/#/R-CFA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Canis familiaris 61120 R-CFA-5687464 https://reactome.org/PathwayBrowser/#/R-CFA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Canis familiaris 61120 R-CFA-5687465 https://reactome.org/PathwayBrowser/#/R-CFA-5687465 MRN complex binds RBBP8 IEA Canis familiaris 61120 R-CFA-5687640 https://reactome.org/PathwayBrowser/#/R-CFA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Canis familiaris 61120 R-CFA-5687664 https://reactome.org/PathwayBrowser/#/R-CFA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Canis familiaris 61120 R-CFA-5687673 https://reactome.org/PathwayBrowser/#/R-CFA-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites IEA Canis familiaris 61120 R-CFA-5687675 https://reactome.org/PathwayBrowser/#/R-CFA-5687675 LIG3 ligates remaining SSBs in MMEJ IEA Canis familiaris 61120 R-CFA-5689317 https://reactome.org/PathwayBrowser/#/R-CFA-5689317 Formation of the pre-incision complex in GG-NER IEA Canis familiaris 61120 R-CFA-5689861 https://reactome.org/PathwayBrowser/#/R-CFA-5689861 Recruitment of XPA and release of CAK IEA Canis familiaris 61120 R-CFA-5690213 https://reactome.org/PathwayBrowser/#/R-CFA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Canis familiaris 61120 R-CFA-5690988 https://reactome.org/PathwayBrowser/#/R-CFA-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Canis familiaris 61120 R-CFA-5690990 https://reactome.org/PathwayBrowser/#/R-CFA-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Canis familiaris 61120 R-CFA-5690991 https://reactome.org/PathwayBrowser/#/R-CFA-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Canis familiaris 61120 R-CFA-5690996 https://reactome.org/PathwayBrowser/#/R-CFA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Canis familiaris 61120 R-CFA-5691000 https://reactome.org/PathwayBrowser/#/R-CFA-5691000 TFIIH binds GG-NER site to form a verification complex IEA Canis familiaris 61120 R-CFA-5691001 https://reactome.org/PathwayBrowser/#/R-CFA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Canis familiaris 61120 R-CFA-5691006 https://reactome.org/PathwayBrowser/#/R-CFA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Canis familiaris 61120 R-CFA-5693533 https://reactome.org/PathwayBrowser/#/R-CFA-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends IEA Canis familiaris 61120 R-CFA-5693536 https://reactome.org/PathwayBrowser/#/R-CFA-5693536 ATM phosphorylates MDC1 IEA Canis familiaris 61120 R-CFA-5693539 https://reactome.org/PathwayBrowser/#/R-CFA-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Canis familiaris 61120 R-CFA-5693540 https://reactome.org/PathwayBrowser/#/R-CFA-5693540 MRN activates ATM IEA Canis familiaris 61120 R-CFA-5693542 https://reactome.org/PathwayBrowser/#/R-CFA-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Canis familiaris 61120 R-CFA-5693549 https://reactome.org/PathwayBrowser/#/R-CFA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Canis familiaris 61120 R-CFA-5693551 https://reactome.org/PathwayBrowser/#/R-CFA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Canis familiaris 61120 R-CFA-5693564 https://reactome.org/PathwayBrowser/#/R-CFA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Canis familiaris 61120 R-CFA-5693566 https://reactome.org/PathwayBrowser/#/R-CFA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Canis familiaris 61120 R-CFA-5693574 https://reactome.org/PathwayBrowser/#/R-CFA-5693574 XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ IEA Canis familiaris 61120 R-CFA-5693575 https://reactome.org/PathwayBrowser/#/R-CFA-5693575 DNA-PKcs autophosphorylates IEA Canis familiaris 61120 R-CFA-5693578 https://reactome.org/PathwayBrowser/#/R-CFA-5693578 TDP1 and TDP2 process unligatable DSB ends IEA Canis familiaris 61120 R-CFA-5693580 https://reactome.org/PathwayBrowser/#/R-CFA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Canis familiaris 61120 R-CFA-5693583 https://reactome.org/PathwayBrowser/#/R-CFA-5693583 MDC1 associates with gamma-H2AFX at nuclear foci IEA Canis familiaris 61120 R-CFA-5693584 https://reactome.org/PathwayBrowser/#/R-CFA-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Canis familiaris 61120 R-CFA-5693593 https://reactome.org/PathwayBrowser/#/R-CFA-5693593 D-loop extension by DNA polymerases IEA Canis familiaris 61120 R-CFA-5693598 https://reactome.org/PathwayBrowser/#/R-CFA-5693598 ATM phosphorylates NBN IEA Canis familiaris 61120 R-CFA-5693608 https://reactome.org/PathwayBrowser/#/R-CFA-5693608 Initial resection of double-strand break ends IEA Canis familiaris 61120 R-CFA-5693612 https://reactome.org/PathwayBrowser/#/R-CFA-5693612 MRN complex bound to DNA ends recruits ATM IEA Canis familiaris 61120 R-CFA-5693615 https://reactome.org/PathwayBrowser/#/R-CFA-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis IEA Canis familiaris 61120 R-CFA-5693620 https://reactome.org/PathwayBrowser/#/R-CFA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Canis familiaris 61120 R-CFA-5696655 https://reactome.org/PathwayBrowser/#/R-CFA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Canis familiaris 61120 R-CFA-5696664 https://reactome.org/PathwayBrowser/#/R-CFA-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Canis familiaris 61120 R-CFA-5696670 https://reactome.org/PathwayBrowser/#/R-CFA-5696670 CHD1L is recruited to GG-NER site IEA Canis familiaris 61120 R-CFA-6781818 https://reactome.org/PathwayBrowser/#/R-CFA-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Canis familiaris 61120 R-CFA-6781824 https://reactome.org/PathwayBrowser/#/R-CFA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Canis familiaris 61120 R-CFA-6781833 https://reactome.org/PathwayBrowser/#/R-CFA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Canis familiaris 61120 R-CFA-6781840 https://reactome.org/PathwayBrowser/#/R-CFA-6781840 ERCC6 binds stalled RNA Pol II IEA Canis familiaris 61120 R-CFA-6781867 https://reactome.org/PathwayBrowser/#/R-CFA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Canis familiaris 61120 R-CFA-6782004 https://reactome.org/PathwayBrowser/#/R-CFA-6782004 Assembly of the pre-incision complex in TC-NER IEA Canis familiaris 61120 R-CFA-6782069 https://reactome.org/PathwayBrowser/#/R-CFA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Canis familiaris 61120 R-CFA-6782131 https://reactome.org/PathwayBrowser/#/R-CFA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Canis familiaris 61120 R-CFA-6782138 https://reactome.org/PathwayBrowser/#/R-CFA-6782138 ERCC5 and RPA bind TC-NER site IEA Canis familiaris 61120 R-CFA-6782141 https://reactome.org/PathwayBrowser/#/R-CFA-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Canis familiaris 61120 R-CFA-6782204 https://reactome.org/PathwayBrowser/#/R-CFA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Canis familiaris 61120 R-CFA-6782208 https://reactome.org/PathwayBrowser/#/R-CFA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Canis familiaris 61120 R-CFA-6782211 https://reactome.org/PathwayBrowser/#/R-CFA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Canis familiaris 61120 R-CFA-6782224 https://reactome.org/PathwayBrowser/#/R-CFA-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Canis familiaris 61120 R-CFA-6782227 https://reactome.org/PathwayBrowser/#/R-CFA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Canis familiaris 61120 R-CFA-6782943 https://reactome.org/PathwayBrowser/#/R-CFA-6782943 UV-DDB ubiquitinates XPC IEA Canis familiaris 61120 R-CFA-6786166 https://reactome.org/PathwayBrowser/#/R-CFA-6786166 Translesion synthesis across unhooked ICL by POLN IEA Canis familiaris 61120 R-CFA-6790487 https://reactome.org/PathwayBrowser/#/R-CFA-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Canis familiaris 61120 R-CFA-6792712 https://reactome.org/PathwayBrowser/#/R-CFA-6792712 KAT5 acetylates ATM at shortened telomeres IEA Canis familiaris 61120 R-CFA-6799332 https://reactome.org/PathwayBrowser/#/R-CFA-6799332 ATR phosphorylates TP53 IEA Canis familiaris 61120 R-CFA-68913 https://reactome.org/PathwayBrowser/#/R-CFA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Canis familiaris 61120 R-CFA-68914 https://reactome.org/PathwayBrowser/#/R-CFA-68914 DNA polymerase alpha:primase binds at the origin IEA Canis familiaris 61120 R-CFA-68944 https://reactome.org/PathwayBrowser/#/R-CFA-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Canis familiaris 61120 R-CFA-68950 https://reactome.org/PathwayBrowser/#/R-CFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Canis familiaris 61120 R-CFA-68960 https://reactome.org/PathwayBrowser/#/R-CFA-68960 DNA polymerase epsilon binds at the origin IEA Canis familiaris 61120 R-CFA-69053 https://reactome.org/PathwayBrowser/#/R-CFA-69053 RFC binding displaces Pol Alpha IEA Canis familiaris 61120 R-CFA-69063 https://reactome.org/PathwayBrowser/#/R-CFA-69063 Loading of PCNA - Sliding Clamp Formation IEA Canis familiaris 61120 R-CFA-69068 https://reactome.org/PathwayBrowser/#/R-CFA-69068 RFC dissociates after sliding clamp formation IEA Canis familiaris 61120 R-CFA-69074 https://reactome.org/PathwayBrowser/#/R-CFA-69074 Formation of Processive Complex IEA Canis familiaris 61120 R-CFA-69116 https://reactome.org/PathwayBrowser/#/R-CFA-69116 Formation of Okazaki fragments IEA Canis familiaris 61120 R-CFA-69127 https://reactome.org/PathwayBrowser/#/R-CFA-69127 Formation of the Flap Intermediate IEA Canis familiaris 61120 R-CFA-69140 https://reactome.org/PathwayBrowser/#/R-CFA-69140 RPA binds to the Flap IEA Canis familiaris 61120 R-CFA-69142 https://reactome.org/PathwayBrowser/#/R-CFA-69142 Recruitment of Dna2 endonuclease IEA Canis familiaris 61120 R-CFA-69144 https://reactome.org/PathwayBrowser/#/R-CFA-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Canis familiaris 61120 R-CFA-69152 https://reactome.org/PathwayBrowser/#/R-CFA-69152 Removal of remaining Flap IEA Canis familiaris 61120 R-CFA-69173 https://reactome.org/PathwayBrowser/#/R-CFA-69173 Joining of adjacent Okazaki fragments IEA Canis familiaris 61120 R-CFA-69891 https://reactome.org/PathwayBrowser/#/R-CFA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Canis familiaris 61120 R-CFA-73718 https://reactome.org/PathwayBrowser/#/R-CFA-73718 UBF-1 Binds rDNA Promoter IEA Canis familiaris 61120 R-CFA-73722 https://reactome.org/PathwayBrowser/#/R-CFA-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Canis familiaris 61120 R-CFA-73739 https://reactome.org/PathwayBrowser/#/R-CFA-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Canis familiaris 61120 R-CFA-73758 https://reactome.org/PathwayBrowser/#/R-CFA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Canis familiaris 61120 R-CFA-73769 https://reactome.org/PathwayBrowser/#/R-CFA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Canis familiaris 61120 R-CFA-73946 https://reactome.org/PathwayBrowser/#/R-CFA-73946 Abortive initiation after formation of the first phosphodiester bond IEA Canis familiaris 61120 R-CFA-75095 https://reactome.org/PathwayBrowser/#/R-CFA-75095 Binding of TFIIE to the growing preinitiation complex IEA Canis familiaris 61120 R-CFA-75850 https://reactome.org/PathwayBrowser/#/R-CFA-75850 Addition of the third nucleotide on the nascent transcript IEA Canis familiaris 61120 R-CFA-75856 https://reactome.org/PathwayBrowser/#/R-CFA-75856 Abortive Initiation Before Second Transition IEA Canis familiaris 61120 R-CFA-75861 https://reactome.org/PathwayBrowser/#/R-CFA-75861 NTP Binds Active Site of RNA Polymerase II IEA Canis familiaris 61120 R-CFA-75862 https://reactome.org/PathwayBrowser/#/R-CFA-75862 Fall Back to Closed Pre-initiation Complex IEA Canis familiaris 61120 R-CFA-75864 https://reactome.org/PathwayBrowser/#/R-CFA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Canis familiaris 61120 R-CFA-75866 https://reactome.org/PathwayBrowser/#/R-CFA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Canis familiaris 61120 R-CFA-75869 https://reactome.org/PathwayBrowser/#/R-CFA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Canis familiaris 61120 R-CFA-75873 https://reactome.org/PathwayBrowser/#/R-CFA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Canis familiaris 61120 R-CFA-75891 https://reactome.org/PathwayBrowser/#/R-CFA-75891 Abortive Initiation After Second Transition IEA Canis familiaris 61120 R-CFA-75949 https://reactome.org/PathwayBrowser/#/R-CFA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Canis familiaris 61120 R-CFA-76052 https://reactome.org/PathwayBrowser/#/R-CFA-76052 Binding of TFIIIA To type 1 Promoter IEA Canis familiaris 61120 R-CFA-76054 https://reactome.org/PathwayBrowser/#/R-CFA-76054 Binding of TFIIIC to TFIIIA:Type I Promoter complex IEA Canis familiaris 61120 R-CFA-76056 https://reactome.org/PathwayBrowser/#/R-CFA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Canis familiaris 61120 R-CFA-76576 https://reactome.org/PathwayBrowser/#/R-CFA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Canis familiaris 61120 R-CFA-77068 https://reactome.org/PathwayBrowser/#/R-CFA-77068 Activation of GT IEA Canis familiaris 61120 R-CFA-77069 https://reactome.org/PathwayBrowser/#/R-CFA-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Canis familiaris 61120 R-CFA-77071 https://reactome.org/PathwayBrowser/#/R-CFA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Canis familiaris 61120 R-CFA-77073 https://reactome.org/PathwayBrowser/#/R-CFA-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Canis familiaris 61120 R-CFA-77077 https://reactome.org/PathwayBrowser/#/R-CFA-77077 Capping complex formation IEA Canis familiaris 61120 R-CFA-77078 https://reactome.org/PathwayBrowser/#/R-CFA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Canis familiaris 61120 R-CFA-77081 https://reactome.org/PathwayBrowser/#/R-CFA-77081 Formation of the CE:GMP intermediate complex IEA Canis familiaris 61120 R-CFA-77083 https://reactome.org/PathwayBrowser/#/R-CFA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Canis familiaris 61120 R-CFA-77085 https://reactome.org/PathwayBrowser/#/R-CFA-77085 Dissociation of transcript with 5'-GMP from GT IEA Canis familiaris 61120 R-CFA-77090 https://reactome.org/PathwayBrowser/#/R-CFA-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Canis familiaris 61120 R-CFA-83723 https://reactome.org/PathwayBrowser/#/R-CFA-83723 Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex IEA Canis familiaris 61120 R-CFA-83788 https://reactome.org/PathwayBrowser/#/R-CFA-83788 Binding of TFIIIC to Type 2 promoter IEA Canis familiaris 61120 R-CFA-83790 https://reactome.org/PathwayBrowser/#/R-CFA-83790 Binding of TFIIIB to TFIIC: Type 2 Promoter Complex IEA Canis familiaris 61120 R-CFA-83791 https://reactome.org/PathwayBrowser/#/R-CFA-83791 Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter IEA Canis familiaris 61120 R-CFA-83793 https://reactome.org/PathwayBrowser/#/R-CFA-83793 Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex IEA Canis familiaris 61120 R-CFA-83803 https://reactome.org/PathwayBrowser/#/R-CFA-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Canis familiaris 61120 R-CFA-83805 https://reactome.org/PathwayBrowser/#/R-CFA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Canis familiaris 61120 R-CFA-9604480 https://reactome.org/PathwayBrowser/#/R-CFA-9604480 NFkB complex translocates from the cytosol to the nucleus IEA Canis familiaris 61120 R-CFA-9613494 https://reactome.org/PathwayBrowser/#/R-CFA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Canis familiaris 61120 R-CFA-9613497 https://reactome.org/PathwayBrowser/#/R-CFA-9613497 Unwinding DNA for the nascent transcript IEA Canis familiaris 61120 R-CFA-9684118 https://reactome.org/PathwayBrowser/#/R-CFA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Canis familiaris 61120 R-CFA-9734475 https://reactome.org/PathwayBrowser/#/R-CFA-9734475 PPARA binds fibrates IEA Canis familiaris 61120 R-CFA-996727 https://reactome.org/PathwayBrowser/#/R-CFA-996727 REST recruits the BHC complex IEA Canis familiaris 61120 R-DDI-109636 https://reactome.org/PathwayBrowser/#/R-DDI-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Dictyostelium discoideum 61120 R-DDI-109637 https://reactome.org/PathwayBrowser/#/R-DDI-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Dictyostelium discoideum 61120 R-DDI-109638 https://reactome.org/PathwayBrowser/#/R-DDI-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Dictyostelium discoideum 61120 R-DDI-109639 https://reactome.org/PathwayBrowser/#/R-DDI-109639 Formation of the closed pre-initiation complex IEA Dictyostelium discoideum 61120 R-DDI-111264 https://reactome.org/PathwayBrowser/#/R-DDI-111264 Addition of nucleotides between position +11 and +30 IEA Dictyostelium discoideum 61120 R-DDI-113430 https://reactome.org/PathwayBrowser/#/R-DDI-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Dictyostelium discoideum 61120 R-DDI-113503 https://reactome.org/PathwayBrowser/#/R-DDI-113503 PP2A mediated localization of RB1 protein in chromatin IEA Dictyostelium discoideum 61120 R-DDI-113504 https://reactome.org/PathwayBrowser/#/R-DDI-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Dictyostelium discoideum 61120 R-DDI-163296 https://reactome.org/PathwayBrowser/#/R-DDI-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Dictyostelium discoideum 61120 R-DDI-163310 https://reactome.org/PathwayBrowser/#/R-DDI-163310 TFAM binds to mitochondrial promoters IEA Dictyostelium discoideum 61120 R-DDI-176264 https://reactome.org/PathwayBrowser/#/R-DDI-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Dictyostelium discoideum 61120 R-DDI-3134954 https://reactome.org/PathwayBrowser/#/R-DDI-3134954 DHX9 binds DNA IEA Dictyostelium discoideum 61120 R-DDI-3134962 https://reactome.org/PathwayBrowser/#/R-DDI-3134962 DHX36 binds DNA IEA Dictyostelium discoideum 61120 R-DDI-5682026 https://reactome.org/PathwayBrowser/#/R-DDI-5682026 MRN bound to shortened telomeres activates ATM IEA Dictyostelium discoideum 61120 R-DDI-5682044 https://reactome.org/PathwayBrowser/#/R-DDI-5682044 KAT5 acetylates ATM at DNA DSBs IEA Dictyostelium discoideum 61120 R-DDI-5682588 https://reactome.org/PathwayBrowser/#/R-DDI-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Dictyostelium discoideum 61120 R-DDI-5682965 https://reactome.org/PathwayBrowser/#/R-DDI-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Dictyostelium discoideum 61120 R-DDI-5682967 https://reactome.org/PathwayBrowser/#/R-DDI-5682967 WHSC1 binds DNA DSBs IEA Dictyostelium discoideum 61120 R-DDI-5682983 https://reactome.org/PathwayBrowser/#/R-DDI-5682983 ATM phosphorylates WHSC1 IEA Dictyostelium discoideum 61120 R-DDI-5683405 https://reactome.org/PathwayBrowser/#/R-DDI-5683405 PPP5C dephosphorylates TP53BP1 IEA Dictyostelium discoideum 61120 R-DDI-5683425 https://reactome.org/PathwayBrowser/#/R-DDI-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Dictyostelium discoideum 61120 R-DDI-5687183 https://reactome.org/PathwayBrowser/#/R-DDI-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Dictyostelium discoideum 61120 R-DDI-5687360 https://reactome.org/PathwayBrowser/#/R-DDI-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Dictyostelium discoideum 61120 R-DDI-5690996 https://reactome.org/PathwayBrowser/#/R-DDI-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Dictyostelium discoideum 61120 R-DDI-5691000 https://reactome.org/PathwayBrowser/#/R-DDI-5691000 TFIIH binds GG-NER site to form a verification complex IEA Dictyostelium discoideum 61120 R-DDI-5691001 https://reactome.org/PathwayBrowser/#/R-DDI-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Dictyostelium discoideum 61120 R-DDI-5691006 https://reactome.org/PathwayBrowser/#/R-DDI-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Dictyostelium discoideum 61120 R-DDI-5693533 https://reactome.org/PathwayBrowser/#/R-DDI-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends IEA Dictyostelium discoideum 61120 R-DDI-5693536 https://reactome.org/PathwayBrowser/#/R-DDI-5693536 ATM phosphorylates MDC1 IEA Dictyostelium discoideum 61120 R-DDI-5693540 https://reactome.org/PathwayBrowser/#/R-DDI-5693540 MRN activates ATM IEA Dictyostelium discoideum 61120 R-DDI-5693549 https://reactome.org/PathwayBrowser/#/R-DDI-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Dictyostelium discoideum 61120 R-DDI-5693566 https://reactome.org/PathwayBrowser/#/R-DDI-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Dictyostelium discoideum 61120 R-DDI-5693575 https://reactome.org/PathwayBrowser/#/R-DDI-5693575 DNA-PKcs autophosphorylates IEA Dictyostelium discoideum 61120 R-DDI-5693578 https://reactome.org/PathwayBrowser/#/R-DDI-5693578 TDP1 and TDP2 process unligatable DSB ends IEA Dictyostelium discoideum 61120 R-DDI-5693598 https://reactome.org/PathwayBrowser/#/R-DDI-5693598 ATM phosphorylates NBN IEA Dictyostelium discoideum 61120 R-DDI-5693602 https://reactome.org/PathwayBrowser/#/R-DDI-5693602 ATM recognizes H2AFX-Nucleosomes IEA Dictyostelium discoideum 61120 R-DDI-5693615 https://reactome.org/PathwayBrowser/#/R-DDI-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis IEA Dictyostelium discoideum 61120 R-DDI-5696655 https://reactome.org/PathwayBrowser/#/R-DDI-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Dictyostelium discoideum 61120 R-DDI-5696664 https://reactome.org/PathwayBrowser/#/R-DDI-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Dictyostelium discoideum 61120 R-DDI-6781818 https://reactome.org/PathwayBrowser/#/R-DDI-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Dictyostelium discoideum 61120 R-DDI-6781824 https://reactome.org/PathwayBrowser/#/R-DDI-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Dictyostelium discoideum 61120 R-DDI-6781833 https://reactome.org/PathwayBrowser/#/R-DDI-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Dictyostelium discoideum 61120 R-DDI-6781840 https://reactome.org/PathwayBrowser/#/R-DDI-6781840 ERCC6 binds stalled RNA Pol II IEA Dictyostelium discoideum 61120 R-DDI-6781867 https://reactome.org/PathwayBrowser/#/R-DDI-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Dictyostelium discoideum 61120 R-DDI-6782069 https://reactome.org/PathwayBrowser/#/R-DDI-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Dictyostelium discoideum 61120 R-DDI-6782131 https://reactome.org/PathwayBrowser/#/R-DDI-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Dictyostelium discoideum 61120 R-DDI-6782141 https://reactome.org/PathwayBrowser/#/R-DDI-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Dictyostelium discoideum 61120 R-DDI-6782204 https://reactome.org/PathwayBrowser/#/R-DDI-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Dictyostelium discoideum 61120 R-DDI-6782208 https://reactome.org/PathwayBrowser/#/R-DDI-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Dictyostelium discoideum 61120 R-DDI-6782211 https://reactome.org/PathwayBrowser/#/R-DDI-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Dictyostelium discoideum 61120 R-DDI-6782227 https://reactome.org/PathwayBrowser/#/R-DDI-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Dictyostelium discoideum 61120 R-DDI-6782943 https://reactome.org/PathwayBrowser/#/R-DDI-6782943 UV-DDB ubiquitinates XPC IEA Dictyostelium discoideum 61120 R-DDI-6792712 https://reactome.org/PathwayBrowser/#/R-DDI-6792712 KAT5 acetylates ATM at shortened telomeres IEA Dictyostelium discoideum 61120 R-DDI-68913 https://reactome.org/PathwayBrowser/#/R-DDI-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Dictyostelium discoideum 61120 R-DDI-68914 https://reactome.org/PathwayBrowser/#/R-DDI-68914 DNA polymerase alpha:primase binds at the origin IEA Dictyostelium discoideum 61120 R-DDI-68950 https://reactome.org/PathwayBrowser/#/R-DDI-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Dictyostelium discoideum 61120 R-DDI-68960 https://reactome.org/PathwayBrowser/#/R-DDI-68960 DNA polymerase epsilon binds at the origin IEA Dictyostelium discoideum 61120 R-DDI-69053 https://reactome.org/PathwayBrowser/#/R-DDI-69053 RFC binding displaces Pol Alpha IEA Dictyostelium discoideum 61120 R-DDI-69063 https://reactome.org/PathwayBrowser/#/R-DDI-69063 Loading of PCNA - Sliding Clamp Formation IEA Dictyostelium discoideum 61120 R-DDI-69068 https://reactome.org/PathwayBrowser/#/R-DDI-69068 RFC dissociates after sliding clamp formation IEA Dictyostelium discoideum 61120 R-DDI-69074 https://reactome.org/PathwayBrowser/#/R-DDI-69074 Formation of Processive Complex IEA Dictyostelium discoideum 61120 R-DDI-69116 https://reactome.org/PathwayBrowser/#/R-DDI-69116 Formation of Okazaki fragments IEA Dictyostelium discoideum 61120 R-DDI-69127 https://reactome.org/PathwayBrowser/#/R-DDI-69127 Formation of the Flap Intermediate IEA Dictyostelium discoideum 61120 R-DDI-69142 https://reactome.org/PathwayBrowser/#/R-DDI-69142 Recruitment of Dna2 endonuclease IEA Dictyostelium discoideum 61120 R-DDI-69152 https://reactome.org/PathwayBrowser/#/R-DDI-69152 Removal of remaining Flap IEA Dictyostelium discoideum 61120 R-DDI-69173 https://reactome.org/PathwayBrowser/#/R-DDI-69173 Joining of adjacent Okazaki fragments IEA Dictyostelium discoideum 61120 R-DDI-73769 https://reactome.org/PathwayBrowser/#/R-DDI-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Dictyostelium discoideum 61120 R-DDI-73946 https://reactome.org/PathwayBrowser/#/R-DDI-73946 Abortive initiation after formation of the first phosphodiester bond IEA Dictyostelium discoideum 61120 R-DDI-75095 https://reactome.org/PathwayBrowser/#/R-DDI-75095 Binding of TFIIE to the growing preinitiation complex IEA Dictyostelium discoideum 61120 R-DDI-75850 https://reactome.org/PathwayBrowser/#/R-DDI-75850 Addition of the third nucleotide on the nascent transcript IEA Dictyostelium discoideum 61120 R-DDI-75856 https://reactome.org/PathwayBrowser/#/R-DDI-75856 Abortive Initiation Before Second Transition IEA Dictyostelium discoideum 61120 R-DDI-75861 https://reactome.org/PathwayBrowser/#/R-DDI-75861 NTP Binds Active Site of RNA Polymerase II IEA Dictyostelium discoideum 61120 R-DDI-75862 https://reactome.org/PathwayBrowser/#/R-DDI-75862 Fall Back to Closed Pre-initiation Complex IEA Dictyostelium discoideum 61120 R-DDI-75864 https://reactome.org/PathwayBrowser/#/R-DDI-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Dictyostelium discoideum 61120 R-DDI-75866 https://reactome.org/PathwayBrowser/#/R-DDI-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Dictyostelium discoideum 61120 R-DDI-75869 https://reactome.org/PathwayBrowser/#/R-DDI-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Dictyostelium discoideum 61120 R-DDI-75873 https://reactome.org/PathwayBrowser/#/R-DDI-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Dictyostelium discoideum 61120 R-DDI-75891 https://reactome.org/PathwayBrowser/#/R-DDI-75891 Abortive Initiation After Second Transition IEA Dictyostelium discoideum 61120 R-DDI-75949 https://reactome.org/PathwayBrowser/#/R-DDI-75949 RNA Polymerase II Promoter Opening: First Transition IEA Dictyostelium discoideum 61120 R-DDI-76052 https://reactome.org/PathwayBrowser/#/R-DDI-76052 Binding of TFIIIA To type 1 Promoter IEA Dictyostelium discoideum 61120 R-DDI-76054 https://reactome.org/PathwayBrowser/#/R-DDI-76054 Binding of TFIIIC to TFIIIA:Type I Promoter complex IEA Dictyostelium discoideum 61120 R-DDI-76056 https://reactome.org/PathwayBrowser/#/R-DDI-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Dictyostelium discoideum 61120 R-DDI-76576 https://reactome.org/PathwayBrowser/#/R-DDI-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Dictyostelium discoideum 61120 R-DDI-77068 https://reactome.org/PathwayBrowser/#/R-DDI-77068 Activation of GT IEA Dictyostelium discoideum 61120 R-DDI-77069 https://reactome.org/PathwayBrowser/#/R-DDI-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Dictyostelium discoideum 61120 R-DDI-77071 https://reactome.org/PathwayBrowser/#/R-DDI-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Dictyostelium discoideum 61120 R-DDI-77073 https://reactome.org/PathwayBrowser/#/R-DDI-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Dictyostelium discoideum 61120 R-DDI-77077 https://reactome.org/PathwayBrowser/#/R-DDI-77077 Capping complex formation IEA Dictyostelium discoideum 61120 R-DDI-77078 https://reactome.org/PathwayBrowser/#/R-DDI-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Dictyostelium discoideum 61120 R-DDI-77081 https://reactome.org/PathwayBrowser/#/R-DDI-77081 Formation of the CE:GMP intermediate complex IEA Dictyostelium discoideum 61120 R-DDI-77083 https://reactome.org/PathwayBrowser/#/R-DDI-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Dictyostelium discoideum 61120 R-DDI-77085 https://reactome.org/PathwayBrowser/#/R-DDI-77085 Dissociation of transcript with 5'-GMP from GT IEA Dictyostelium discoideum 61120 R-DDI-77090 https://reactome.org/PathwayBrowser/#/R-DDI-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Dictyostelium discoideum 61120 R-DDI-83723 https://reactome.org/PathwayBrowser/#/R-DDI-83723 Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex IEA Dictyostelium discoideum 61120 R-DDI-83788 https://reactome.org/PathwayBrowser/#/R-DDI-83788 Binding of TFIIIC to Type 2 promoter IEA Dictyostelium discoideum 61120 R-DDI-83790 https://reactome.org/PathwayBrowser/#/R-DDI-83790 Binding of TFIIIB to TFIIC: Type 2 Promoter Complex IEA Dictyostelium discoideum 61120 R-DDI-83805 https://reactome.org/PathwayBrowser/#/R-DDI-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Dictyostelium discoideum 61120 R-DDI-9613494 https://reactome.org/PathwayBrowser/#/R-DDI-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Dictyostelium discoideum 61120 R-DDI-9613497 https://reactome.org/PathwayBrowser/#/R-DDI-9613497 Unwinding DNA for the nascent transcript IEA Dictyostelium discoideum 61120 R-DDI-9684118 https://reactome.org/PathwayBrowser/#/R-DDI-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Dictyostelium discoideum 61120 R-DME-1008200 https://reactome.org/PathwayBrowser/#/R-DME-1008200 NFE2 binds the beta globin locus control region IEA Drosophila melanogaster 61120 R-DME-109636 https://reactome.org/PathwayBrowser/#/R-DME-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Drosophila melanogaster 61120 R-DME-109637 https://reactome.org/PathwayBrowser/#/R-DME-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Drosophila melanogaster 61120 R-DME-109638 https://reactome.org/PathwayBrowser/#/R-DME-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Drosophila melanogaster 61120 R-DME-109639 https://reactome.org/PathwayBrowser/#/R-DME-109639 Formation of the closed pre-initiation complex IEA Drosophila melanogaster 61120 R-DME-111264 https://reactome.org/PathwayBrowser/#/R-DME-111264 Addition of nucleotides between position +11 and +30 IEA Drosophila melanogaster 61120 R-DME-112379 https://reactome.org/PathwayBrowser/#/R-DME-112379 Recruitment of elongation factors to form elongation complex IEA Drosophila melanogaster 61120 R-DME-112385 https://reactome.org/PathwayBrowser/#/R-DME-112385 Addition of nucleotides leads to transcript elongation IEA Drosophila melanogaster 61120 R-DME-113430 https://reactome.org/PathwayBrowser/#/R-DME-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Drosophila melanogaster 61120 R-DME-113504 https://reactome.org/PathwayBrowser/#/R-DME-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Drosophila melanogaster 61120 R-DME-113649 https://reactome.org/PathwayBrowser/#/R-DME-113649 Replication initiation regulation by E2F1/Rbf1 TAS Drosophila melanogaster 61120 R-DME-1535903 https://reactome.org/PathwayBrowser/#/R-DME-1535903 Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements IEA Drosophila melanogaster 61120 R-DME-163296 https://reactome.org/PathwayBrowser/#/R-DME-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Drosophila melanogaster 61120 R-DME-163310 https://reactome.org/PathwayBrowser/#/R-DME-163310 TFAM binds to mitochondrial promoters IEA Drosophila melanogaster 61120 R-DME-163320 https://reactome.org/PathwayBrowser/#/R-DME-163320 Association of mTERF with the termination sequence IEA Drosophila melanogaster 61120 R-DME-176101 https://reactome.org/PathwayBrowser/#/R-DME-176101 Recruitment of Rad17-RFC complex to DNA IEA Drosophila melanogaster 61120 R-DME-176175 https://reactome.org/PathwayBrowser/#/R-DME-176175 Stalling of DNA replication fork and RPA binding IEA Drosophila melanogaster 61120 R-DME-176250 https://reactome.org/PathwayBrowser/#/R-DME-176250 Binding of ATR-ATRIP to the RPA-ssDNA complex IEA Drosophila melanogaster 61120 R-DME-176264 https://reactome.org/PathwayBrowser/#/R-DME-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Drosophila melanogaster 61120 R-DME-3134953 https://reactome.org/PathwayBrowser/#/R-DME-3134953 DHX36 or DHX9 binds MyD88 IEA Drosophila melanogaster 61120 R-DME-3134954 https://reactome.org/PathwayBrowser/#/R-DME-3134954 DHX9 binds DNA IEA Drosophila melanogaster 61120 R-DME-3134962 https://reactome.org/PathwayBrowser/#/R-DME-3134962 DHX36 binds DNA IEA Drosophila melanogaster 61120 R-DME-3785768 https://reactome.org/PathwayBrowser/#/R-DME-3785768 MRN complex binds DNA double strand breaks IEA Drosophila melanogaster 61120 R-DME-400143 https://reactome.org/PathwayBrowser/#/R-DME-400143 Fatty acid ligands activate PPARA IEA Drosophila melanogaster 61120 R-DME-400183 https://reactome.org/PathwayBrowser/#/R-DME-400183 PPARA:RXRA binds Corepressors of PPARA IEA Drosophila melanogaster 61120 R-DME-400204 https://reactome.org/PathwayBrowser/#/R-DME-400204 PPARA binds RXRA IEA Drosophila melanogaster 61120 R-DME-5682018 https://reactome.org/PathwayBrowser/#/R-DME-5682018 MRN complex bound to shortened telomeres recruits ATM IEA Drosophila melanogaster 61120 R-DME-5682020 https://reactome.org/PathwayBrowser/#/R-DME-5682020 MRN complex binds shortened telomeres IEA Drosophila melanogaster 61120 R-DME-5682026 https://reactome.org/PathwayBrowser/#/R-DME-5682026 MRN bound to shortened telomeres activates ATM IEA Drosophila melanogaster 61120 R-DME-5682044 https://reactome.org/PathwayBrowser/#/R-DME-5682044 KAT5 acetylates ATM at DNA DSBs IEA Drosophila melanogaster 61120 R-DME-5682586 https://reactome.org/PathwayBrowser/#/R-DME-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Drosophila melanogaster 61120 R-DME-5682598 https://reactome.org/PathwayBrowser/#/R-DME-5682598 ATM phosphorylates HERC2 IEA Drosophila melanogaster 61120 R-DME-5682629 https://reactome.org/PathwayBrowser/#/R-DME-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Drosophila melanogaster 61120 R-DME-5682858 https://reactome.org/PathwayBrowser/#/R-DME-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Drosophila melanogaster 61120 R-DME-5682965 https://reactome.org/PathwayBrowser/#/R-DME-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Drosophila melanogaster 61120 R-DME-5682983 https://reactome.org/PathwayBrowser/#/R-DME-5682983 ATM phosphorylates WHSC1 IEA Drosophila melanogaster 61120 R-DME-5682992 https://reactome.org/PathwayBrowser/#/R-DME-5682992 KDM4A,B bind H4K20Me2 IEA Drosophila melanogaster 61120 R-DME-5683077 https://reactome.org/PathwayBrowser/#/R-DME-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Drosophila melanogaster 61120 R-DME-5683964 https://reactome.org/PathwayBrowser/#/R-DME-5683964 ATM phosphorylates EYA1-4 IEA Drosophila melanogaster 61120 R-DME-5683967 https://reactome.org/PathwayBrowser/#/R-DME-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Drosophila melanogaster 61120 R-DME-5684096 https://reactome.org/PathwayBrowser/#/R-DME-5684096 CDK2 phosphorylates RBBP8 IEA Drosophila melanogaster 61120 R-DME-5684140 https://reactome.org/PathwayBrowser/#/R-DME-5684140 ATM phosphorylates RBBP8 IEA Drosophila melanogaster 61120 R-DME-5684882 https://reactome.org/PathwayBrowser/#/R-DME-5684882 CHEK1 is recruited to resected DNA DSBs IEA Drosophila melanogaster 61120 R-DME-5684887 https://reactome.org/PathwayBrowser/#/R-DME-5684887 Activation of CHEK1 at resected DNA DSBs IEA Drosophila melanogaster 61120 R-DME-5685156 https://reactome.org/PathwayBrowser/#/R-DME-5685156 ATR phosphorylates RPA2 IEA Drosophila melanogaster 61120 R-DME-5687464 https://reactome.org/PathwayBrowser/#/R-DME-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Drosophila melanogaster 61120 R-DME-5687484 https://reactome.org/PathwayBrowser/#/R-DME-5687484 PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site IEA Drosophila melanogaster 61120 R-DME-5687640 https://reactome.org/PathwayBrowser/#/R-DME-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Drosophila melanogaster 61120 R-DME-5687653 https://reactome.org/PathwayBrowser/#/R-DME-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Drosophila melanogaster 61120 R-DME-5687664 https://reactome.org/PathwayBrowser/#/R-DME-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Drosophila melanogaster 61120 R-DME-5687673 https://reactome.org/PathwayBrowser/#/R-DME-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites IEA Drosophila melanogaster 61120 R-DME-5689861 https://reactome.org/PathwayBrowser/#/R-DME-5689861 Recruitment of XPA and release of CAK IEA Drosophila melanogaster 61120 R-DME-5690213 https://reactome.org/PathwayBrowser/#/R-DME-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Drosophila melanogaster 61120 R-DME-5690990 https://reactome.org/PathwayBrowser/#/R-DME-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Drosophila melanogaster 61120 R-DME-5690991 https://reactome.org/PathwayBrowser/#/R-DME-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Drosophila melanogaster 61120 R-DME-5690996 https://reactome.org/PathwayBrowser/#/R-DME-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Drosophila melanogaster 61120 R-DME-5691000 https://reactome.org/PathwayBrowser/#/R-DME-5691000 TFIIH binds GG-NER site to form a verification complex IEA Drosophila melanogaster 61120 R-DME-5691001 https://reactome.org/PathwayBrowser/#/R-DME-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Drosophila melanogaster 61120 R-DME-5691006 https://reactome.org/PathwayBrowser/#/R-DME-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Drosophila melanogaster 61120 R-DME-5693536 https://reactome.org/PathwayBrowser/#/R-DME-5693536 ATM phosphorylates MDC1 IEA Drosophila melanogaster 61120 R-DME-5693540 https://reactome.org/PathwayBrowser/#/R-DME-5693540 MRN activates ATM IEA Drosophila melanogaster 61120 R-DME-5693549 https://reactome.org/PathwayBrowser/#/R-DME-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Drosophila melanogaster 61120 R-DME-5693583 https://reactome.org/PathwayBrowser/#/R-DME-5693583 MDC1 associates with gamma-H2AFX at nuclear foci IEA Drosophila melanogaster 61120 R-DME-5693598 https://reactome.org/PathwayBrowser/#/R-DME-5693598 ATM phosphorylates NBN IEA Drosophila melanogaster 61120 R-DME-5693602 https://reactome.org/PathwayBrowser/#/R-DME-5693602 ATM recognizes H2AFX-Nucleosomes IEA Drosophila melanogaster 61120 R-DME-5693612 https://reactome.org/PathwayBrowser/#/R-DME-5693612 MRN complex bound to DNA ends recruits ATM IEA Drosophila melanogaster 61120 R-DME-5696655 https://reactome.org/PathwayBrowser/#/R-DME-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Drosophila melanogaster 61120 R-DME-5696664 https://reactome.org/PathwayBrowser/#/R-DME-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Drosophila melanogaster 61120 R-DME-6781818 https://reactome.org/PathwayBrowser/#/R-DME-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Drosophila melanogaster 61120 R-DME-6781824 https://reactome.org/PathwayBrowser/#/R-DME-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Drosophila melanogaster 61120 R-DME-6781833 https://reactome.org/PathwayBrowser/#/R-DME-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Drosophila melanogaster 61120 R-DME-6781867 https://reactome.org/PathwayBrowser/#/R-DME-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Drosophila melanogaster 61120 R-DME-6782069 https://reactome.org/PathwayBrowser/#/R-DME-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Drosophila melanogaster 61120 R-DME-6782131 https://reactome.org/PathwayBrowser/#/R-DME-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Drosophila melanogaster 61120 R-DME-6782141 https://reactome.org/PathwayBrowser/#/R-DME-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Drosophila melanogaster 61120 R-DME-6782204 https://reactome.org/PathwayBrowser/#/R-DME-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Drosophila melanogaster 61120 R-DME-6782208 https://reactome.org/PathwayBrowser/#/R-DME-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Drosophila melanogaster 61120 R-DME-6782211 https://reactome.org/PathwayBrowser/#/R-DME-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Drosophila melanogaster 61120 R-DME-6782227 https://reactome.org/PathwayBrowser/#/R-DME-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Drosophila melanogaster 61120 R-DME-6782943 https://reactome.org/PathwayBrowser/#/R-DME-6782943 UV-DDB ubiquitinates XPC IEA Drosophila melanogaster 61120 R-DME-6790454 https://reactome.org/PathwayBrowser/#/R-DME-6790454 SUMOylation of XPC IEA Drosophila melanogaster 61120 R-DME-6792712 https://reactome.org/PathwayBrowser/#/R-DME-6792712 KAT5 acetylates ATM at shortened telomeres IEA Drosophila melanogaster 61120 R-DME-6799332 https://reactome.org/PathwayBrowser/#/R-DME-6799332 ATR phosphorylates TP53 IEA Drosophila melanogaster 61120 R-DME-68913 https://reactome.org/PathwayBrowser/#/R-DME-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Drosophila melanogaster 61120 R-DME-68914 https://reactome.org/PathwayBrowser/#/R-DME-68914 DNA polymerase alpha:primase binds at the origin IEA Drosophila melanogaster 61120 R-DME-68944 https://reactome.org/PathwayBrowser/#/R-DME-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Drosophila melanogaster 61120 R-DME-68950 https://reactome.org/PathwayBrowser/#/R-DME-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Drosophila melanogaster 61120 R-DME-68960 https://reactome.org/PathwayBrowser/#/R-DME-68960 DNA polymerase epsilon binds at the origin IEA Drosophila melanogaster 61120 R-DME-69053 https://reactome.org/PathwayBrowser/#/R-DME-69053 RFC binding displaces Pol Alpha IEA Drosophila melanogaster 61120 R-DME-69063 https://reactome.org/PathwayBrowser/#/R-DME-69063 Loading of PCNA - Sliding Clamp Formation IEA Drosophila melanogaster 61120 R-DME-69068 https://reactome.org/PathwayBrowser/#/R-DME-69068 RFC dissociates after sliding clamp formation IEA Drosophila melanogaster 61120 R-DME-69127 https://reactome.org/PathwayBrowser/#/R-DME-69127 Formation of the Flap Intermediate IEA Drosophila melanogaster 61120 R-DME-69140 https://reactome.org/PathwayBrowser/#/R-DME-69140 RPA binds to the Flap IEA Drosophila melanogaster 61120 R-DME-69142 https://reactome.org/PathwayBrowser/#/R-DME-69142 Recruitment of Dna2 endonuclease IEA Drosophila melanogaster 61120 R-DME-69144 https://reactome.org/PathwayBrowser/#/R-DME-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Drosophila melanogaster 61120 R-DME-69152 https://reactome.org/PathwayBrowser/#/R-DME-69152 Removal of remaining Flap IEA Drosophila melanogaster 61120 R-DME-69173 https://reactome.org/PathwayBrowser/#/R-DME-69173 Joining of adjacent Okazaki fragments IEA Drosophila melanogaster 61120 R-DME-73769 https://reactome.org/PathwayBrowser/#/R-DME-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Drosophila melanogaster 61120 R-DME-73946 https://reactome.org/PathwayBrowser/#/R-DME-73946 Abortive initiation after formation of the first phosphodiester bond IEA Drosophila melanogaster 61120 R-DME-75095 https://reactome.org/PathwayBrowser/#/R-DME-75095 Binding of TFIIE to the growing preinitiation complex IEA Drosophila melanogaster 61120 R-DME-75850 https://reactome.org/PathwayBrowser/#/R-DME-75850 Addition of the third nucleotide on the nascent transcript IEA Drosophila melanogaster 61120 R-DME-75856 https://reactome.org/PathwayBrowser/#/R-DME-75856 Abortive Initiation Before Second Transition IEA Drosophila melanogaster 61120 R-DME-75861 https://reactome.org/PathwayBrowser/#/R-DME-75861 NTP Binds Active Site of RNA Polymerase II IEA Drosophila melanogaster 61120 R-DME-75862 https://reactome.org/PathwayBrowser/#/R-DME-75862 Fall Back to Closed Pre-initiation Complex IEA Drosophila melanogaster 61120 R-DME-75864 https://reactome.org/PathwayBrowser/#/R-DME-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Drosophila melanogaster 61120 R-DME-75866 https://reactome.org/PathwayBrowser/#/R-DME-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Drosophila melanogaster 61120 R-DME-75869 https://reactome.org/PathwayBrowser/#/R-DME-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Drosophila melanogaster 61120 R-DME-75873 https://reactome.org/PathwayBrowser/#/R-DME-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Drosophila melanogaster 61120 R-DME-75891 https://reactome.org/PathwayBrowser/#/R-DME-75891 Abortive Initiation After Second Transition IEA Drosophila melanogaster 61120 R-DME-75949 https://reactome.org/PathwayBrowser/#/R-DME-75949 RNA Polymerase II Promoter Opening: First Transition IEA Drosophila melanogaster 61120 R-DME-76056 https://reactome.org/PathwayBrowser/#/R-DME-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Drosophila melanogaster 61120 R-DME-76576 https://reactome.org/PathwayBrowser/#/R-DME-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Drosophila melanogaster 61120 R-DME-77068 https://reactome.org/PathwayBrowser/#/R-DME-77068 Activation of GT IEA Drosophila melanogaster 61120 R-DME-77069 https://reactome.org/PathwayBrowser/#/R-DME-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Drosophila melanogaster 61120 R-DME-77071 https://reactome.org/PathwayBrowser/#/R-DME-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Drosophila melanogaster 61120 R-DME-77073 https://reactome.org/PathwayBrowser/#/R-DME-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Drosophila melanogaster 61120 R-DME-77077 https://reactome.org/PathwayBrowser/#/R-DME-77077 Capping complex formation IEA Drosophila melanogaster 61120 R-DME-77078 https://reactome.org/PathwayBrowser/#/R-DME-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Drosophila melanogaster 61120 R-DME-77081 https://reactome.org/PathwayBrowser/#/R-DME-77081 Formation of the CE:GMP intermediate complex IEA Drosophila melanogaster 61120 R-DME-77083 https://reactome.org/PathwayBrowser/#/R-DME-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Drosophila melanogaster 61120 R-DME-77085 https://reactome.org/PathwayBrowser/#/R-DME-77085 Dissociation of transcript with 5'-GMP from GT IEA Drosophila melanogaster 61120 R-DME-77090 https://reactome.org/PathwayBrowser/#/R-DME-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Drosophila melanogaster 61120 R-DME-83788 https://reactome.org/PathwayBrowser/#/R-DME-83788 Binding of TFIIIC to Type 2 promoter IEA Drosophila melanogaster 61120 R-DME-83790 https://reactome.org/PathwayBrowser/#/R-DME-83790 Binding of TFIIIB to TFIIC: Type 2 Promoter Complex IEA Drosophila melanogaster 61120 R-DME-83805 https://reactome.org/PathwayBrowser/#/R-DME-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Drosophila melanogaster 61120 R-DME-9604480 https://reactome.org/PathwayBrowser/#/R-DME-9604480 NFkB complex translocates from the cytosol to the nucleus IEA Drosophila melanogaster 61120 R-DME-9613494 https://reactome.org/PathwayBrowser/#/R-DME-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Drosophila melanogaster 61120 R-DME-9613497 https://reactome.org/PathwayBrowser/#/R-DME-9613497 Unwinding DNA for the nascent transcript IEA Drosophila melanogaster 61120 R-DME-9684118 https://reactome.org/PathwayBrowser/#/R-DME-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Drosophila melanogaster 61120 R-DME-9734475 https://reactome.org/PathwayBrowser/#/R-DME-9734475 PPARA binds fibrates IEA Drosophila melanogaster 61120 R-DME-996727 https://reactome.org/PathwayBrowser/#/R-DME-996727 REST recruits the BHC complex IEA Drosophila melanogaster 61120 R-DRE-1008200 https://reactome.org/PathwayBrowser/#/R-DRE-1008200 NFE2 binds the beta globin locus control region IEA Danio rerio 61120 R-DRE-113430 https://reactome.org/PathwayBrowser/#/R-DRE-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Danio rerio 61120 R-DRE-113503 https://reactome.org/PathwayBrowser/#/R-DRE-113503 PP2A mediated localization of RB1 protein in chromatin IEA Danio rerio 61120 R-DRE-163310 https://reactome.org/PathwayBrowser/#/R-DRE-163310 TFAM binds to mitochondrial promoters IEA Danio rerio 61120 R-DRE-176101 https://reactome.org/PathwayBrowser/#/R-DRE-176101 Recruitment of Rad17-RFC complex to DNA IEA Danio rerio 61120 R-DRE-176175 https://reactome.org/PathwayBrowser/#/R-DRE-176175 Stalling of DNA replication fork and RPA binding IEA Danio rerio 61120 R-DRE-211247 https://reactome.org/PathwayBrowser/#/R-DRE-211247 Cleavage of DNA by DFF40 IEA Danio rerio 61120 R-DRE-400143 https://reactome.org/PathwayBrowser/#/R-DRE-400143 Fatty acid ligands activate PPARA IEA Danio rerio 61120 R-DRE-400183 https://reactome.org/PathwayBrowser/#/R-DRE-400183 PPARA:RXRA binds Corepressors of PPARA IEA Danio rerio 61120 R-DRE-400204 https://reactome.org/PathwayBrowser/#/R-DRE-400204 PPARA binds RXRA IEA Danio rerio 61120 R-DRE-5690990 https://reactome.org/PathwayBrowser/#/R-DRE-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Danio rerio 61120 R-DRE-5690991 https://reactome.org/PathwayBrowser/#/R-DRE-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Danio rerio 61120 R-DRE-5690996 https://reactome.org/PathwayBrowser/#/R-DRE-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Danio rerio 61120 R-DRE-5691000 https://reactome.org/PathwayBrowser/#/R-DRE-5691000 TFIIH binds GG-NER site to form a verification complex IEA Danio rerio 61120 R-DRE-5696655 https://reactome.org/PathwayBrowser/#/R-DRE-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Danio rerio 61120 R-DRE-5696664 https://reactome.org/PathwayBrowser/#/R-DRE-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Danio rerio 61120 R-DRE-5696670 https://reactome.org/PathwayBrowser/#/R-DRE-5696670 CHD1L is recruited to GG-NER site IEA Danio rerio 61120 R-DRE-6782069 https://reactome.org/PathwayBrowser/#/R-DRE-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Danio rerio 61120 R-DRE-6782131 https://reactome.org/PathwayBrowser/#/R-DRE-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Danio rerio 61120 R-DRE-6782141 https://reactome.org/PathwayBrowser/#/R-DRE-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Danio rerio 61120 R-DRE-6782204 https://reactome.org/PathwayBrowser/#/R-DRE-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Danio rerio 61120 R-DRE-73718 https://reactome.org/PathwayBrowser/#/R-DRE-73718 UBF-1 Binds rDNA Promoter IEA Danio rerio 61120 R-DRE-73722 https://reactome.org/PathwayBrowser/#/R-DRE-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Danio rerio 61120 R-DRE-76052 https://reactome.org/PathwayBrowser/#/R-DRE-76052 Binding of TFIIIA To type 1 Promoter IEA Danio rerio 61120 R-DRE-77068 https://reactome.org/PathwayBrowser/#/R-DRE-77068 Activation of GT IEA Danio rerio 61120 R-DRE-77069 https://reactome.org/PathwayBrowser/#/R-DRE-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Danio rerio 61120 R-DRE-77071 https://reactome.org/PathwayBrowser/#/R-DRE-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Danio rerio 61120 R-DRE-77073 https://reactome.org/PathwayBrowser/#/R-DRE-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Danio rerio 61120 R-DRE-77077 https://reactome.org/PathwayBrowser/#/R-DRE-77077 Capping complex formation IEA Danio rerio 61120 R-DRE-77078 https://reactome.org/PathwayBrowser/#/R-DRE-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Danio rerio 61120 R-DRE-77081 https://reactome.org/PathwayBrowser/#/R-DRE-77081 Formation of the CE:GMP intermediate complex IEA Danio rerio 61120 R-DRE-77083 https://reactome.org/PathwayBrowser/#/R-DRE-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Danio rerio 61120 R-DRE-77085 https://reactome.org/PathwayBrowser/#/R-DRE-77085 Dissociation of transcript with 5'-GMP from GT IEA Danio rerio 61120 R-DRE-9684118 https://reactome.org/PathwayBrowser/#/R-DRE-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Danio rerio 61120 R-DRE-9734475 https://reactome.org/PathwayBrowser/#/R-DRE-9734475 PPARA binds fibrates IEA Danio rerio 61120 R-GGA-1008270 https://reactome.org/PathwayBrowser/#/R-GGA-1008270 Activated TAK1 leaves endosome membrane IEA Gallus gallus 61120 R-GGA-109636 https://reactome.org/PathwayBrowser/#/R-GGA-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Gallus gallus 61120 R-GGA-109637 https://reactome.org/PathwayBrowser/#/R-GGA-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Gallus gallus 61120 R-GGA-109638 https://reactome.org/PathwayBrowser/#/R-GGA-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Gallus gallus 61120 R-GGA-109639 https://reactome.org/PathwayBrowser/#/R-GGA-109639 Formation of the closed pre-initiation complex IEA Gallus gallus 61120 R-GGA-111264 https://reactome.org/PathwayBrowser/#/R-GGA-111264 Addition of nucleotides between position +11 and +30 IEA Gallus gallus 61120 R-GGA-112381 https://reactome.org/PathwayBrowser/#/R-GGA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Gallus gallus 61120 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus 61120 R-GGA-113430 https://reactome.org/PathwayBrowser/#/R-GGA-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Gallus gallus 61120 R-GGA-113504 https://reactome.org/PathwayBrowser/#/R-GGA-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Gallus gallus 61120 R-GGA-163296 https://reactome.org/PathwayBrowser/#/R-GGA-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Gallus gallus 61120 R-GGA-163310 https://reactome.org/PathwayBrowser/#/R-GGA-163310 TFAM binds to mitochondrial promoters IEA Gallus gallus 61120 R-GGA-174427 https://reactome.org/PathwayBrowser/#/R-GGA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Gallus gallus 61120 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus 61120 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus 61120 R-GGA-176101 https://reactome.org/PathwayBrowser/#/R-GGA-176101 Recruitment of Rad17-RFC complex to DNA IEA Gallus gallus 61120 R-GGA-176175 https://reactome.org/PathwayBrowser/#/R-GGA-176175 Stalling of DNA replication fork and RPA binding IEA Gallus gallus 61120 R-GGA-176250 https://reactome.org/PathwayBrowser/#/R-GGA-176250 Binding of ATR-ATRIP to the RPA-ssDNA complex IEA Gallus gallus 61120 R-GGA-176264 https://reactome.org/PathwayBrowser/#/R-GGA-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Gallus gallus 61120 R-GGA-217209 https://reactome.org/PathwayBrowser/#/R-GGA-217209 Generation of a DNA double strand break TAS Gallus gallus 61120 R-GGA-265887 https://reactome.org/PathwayBrowser/#/R-GGA-265887 Binding of RPA heterotrimer to 3' double stranded DNA break TAS Gallus gallus 61120 R-GGA-265894 https://reactome.org/PathwayBrowser/#/R-GGA-265894 BRIP1 (FANCJ) helicase functions in direct unwinding of DNA TAS Gallus gallus 61120 R-GGA-3134953 https://reactome.org/PathwayBrowser/#/R-GGA-3134953 DHX36 or DHX9 binds MyD88 IEA Gallus gallus 61120 R-GGA-3134962 https://reactome.org/PathwayBrowser/#/R-GGA-3134962 DHX36 binds DNA IEA Gallus gallus 61120 R-GGA-351429 https://reactome.org/PathwayBrowser/#/R-GGA-351429 Association of 53BP1 with gamma H2AX at double strand break TAS Gallus gallus 61120 R-GGA-351456 https://reactome.org/PathwayBrowser/#/R-GGA-351456 Association of gamma H2AX and NBS1 TAS Gallus gallus 61120 R-GGA-353226 https://reactome.org/PathwayBrowser/#/R-GGA-353226 Association of Ku heterodimer with ends of DNA double-strand breaks TAS Gallus gallus 61120 R-GGA-353243 https://reactome.org/PathwayBrowser/#/R-GGA-353243 Monoubiquitunated PCNA mediates recruitment of the translesion polymerase to the DNA damaged site. TAS Gallus gallus 61120 R-GGA-353265 https://reactome.org/PathwayBrowser/#/R-GGA-353265 Interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB IEA Gallus gallus 61120 R-GGA-353268 https://reactome.org/PathwayBrowser/#/R-GGA-353268 Binding of Pol zeta complex to a DNA template containing lesions TAS Gallus gallus 61120 R-GGA-353273 https://reactome.org/PathwayBrowser/#/R-GGA-353273 Elongation by Pol zeta complex TAS Gallus gallus 61120 R-GGA-353283 https://reactome.org/PathwayBrowser/#/R-GGA-353283 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks TAS Gallus gallus 61120 R-GGA-353298 https://reactome.org/PathwayBrowser/#/R-GGA-353298 Removal of repair proteins and ligation of the processed ends of the DNA double-strand break TAS Gallus gallus 61120 R-GGA-353300 https://reactome.org/PathwayBrowser/#/R-GGA-353300 MGMT mediated DNA Damage Reversal TAS Gallus gallus 61120 R-GGA-353301 https://reactome.org/PathwayBrowser/#/R-GGA-353301 Binding of Pol kappa and REV1 complex to the lesion on the template DNA strand TAS Gallus gallus 61120 R-GGA-353313 https://reactome.org/PathwayBrowser/#/R-GGA-353313 Removal of 3'-phosphoglycolate (PG) moiety from DSB ends TAS Gallus gallus 61120 R-GGA-353314 https://reactome.org/PathwayBrowser/#/R-GGA-353314 XP-C-RAD23B heterodimer binds to damaged DNA site with lesion IEA Gallus gallus 61120 R-GGA-353318 https://reactome.org/PathwayBrowser/#/R-GGA-353318 Insertion of correct bases opposite to the lesion by Pol kappa TAS Gallus gallus 61120 R-GGA-353323 https://reactome.org/PathwayBrowser/#/R-GGA-353323 Ligation of newly synthesized repair patch to incised DNA in GG-NER TAS Gallus gallus 61120 R-GGA-353356 https://reactome.org/PathwayBrowser/#/R-GGA-353356 Reversal of Alkylation Damage By DNA Dioxygenases TAS Gallus gallus 61120 R-GGA-353430 https://reactome.org/PathwayBrowser/#/R-GGA-353430 Binding of Pol eta to a DNA template containing a lesion TAS Gallus gallus 61120 R-GGA-353435 https://reactome.org/PathwayBrowser/#/R-GGA-353435 Elongation by Pol eta TAS Gallus gallus 61120 R-GGA-353475 https://reactome.org/PathwayBrowser/#/R-GGA-353475 Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex IEA Gallus gallus 61120 R-GGA-353476 https://reactome.org/PathwayBrowser/#/R-GGA-353476 Recruitment of repair factors to form the preincision complex TAS Gallus gallus 61120 R-GGA-353494 https://reactome.org/PathwayBrowser/#/R-GGA-353494 Elongation by Pol kappa TAS Gallus gallus 61120 R-GGA-353504 https://reactome.org/PathwayBrowser/#/R-GGA-353504 Insertion of correct bases opposite to the lesion by Pol eta TAS Gallus gallus 61120 R-GGA-353516 https://reactome.org/PathwayBrowser/#/R-GGA-353516 Ligation of DNA at sites of patch replacement TAS Gallus gallus 61120 R-GGA-353526 https://reactome.org/PathwayBrowser/#/R-GGA-353526 Repair of ~27-30 bp long patch by DNA Pol Epsilon IEA Gallus gallus 61120 R-GGA-3785768 https://reactome.org/PathwayBrowser/#/R-GGA-3785768 MRN complex binds DNA double strand breaks IEA Gallus gallus 61120 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus 61120 R-GGA-400183 https://reactome.org/PathwayBrowser/#/R-GGA-400183 PPARA:RXRA binds Corepressors of PPARA IEA Gallus gallus 61120 R-GGA-400204 https://reactome.org/PathwayBrowser/#/R-GGA-400204 PPARA binds RXRA IEA Gallus gallus 61120 R-GGA-451439 https://reactome.org/PathwayBrowser/#/R-GGA-451439 Activated TLR7 or 21 recruits MyD88 IEA Gallus gallus 61120 R-GGA-451461 https://reactome.org/PathwayBrowser/#/R-GGA-451461 IRAK4 binds to the activated TLR7 or 21 IEA Gallus gallus 61120 R-GGA-451506 https://reactome.org/PathwayBrowser/#/R-GGA-451506 TLR21homodimer binds to DNA TAS Gallus gallus 61120 R-GGA-5250930 https://reactome.org/PathwayBrowser/#/R-GGA-5250930 B-WICH recruits histone acetyltransferases IEA Gallus gallus 61120 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus 61120 R-GGA-5250947 https://reactome.org/PathwayBrowser/#/R-GGA-5250947 B-WICH complex binds rDNA promoter IEA Gallus gallus 61120 R-GGA-532630 https://reactome.org/PathwayBrowser/#/R-GGA-532630 p-IRAK2- TRAF6 dissociates from the activated TRL7 or 21 IEA Gallus gallus 61120 R-GGA-532632 https://reactome.org/PathwayBrowser/#/R-GGA-532632 TRAF6 binds to p-IRAK2 complexed with activated TLR7 or TLR21 IEA Gallus gallus 61120 R-GGA-5682018 https://reactome.org/PathwayBrowser/#/R-GGA-5682018 MRN complex bound to shortened telomeres recruits ATM IEA Gallus gallus 61120 R-GGA-5682020 https://reactome.org/PathwayBrowser/#/R-GGA-5682020 MRN complex binds shortened telomeres IEA Gallus gallus 61120 R-GGA-5682026 https://reactome.org/PathwayBrowser/#/R-GGA-5682026 MRN bound to shortened telomeres activates ATM IEA Gallus gallus 61120 R-GGA-5682044 https://reactome.org/PathwayBrowser/#/R-GGA-5682044 KAT5 acetylates ATM at DNA DSBs IEA Gallus gallus 61120 R-GGA-5682586 https://reactome.org/PathwayBrowser/#/R-GGA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Gallus gallus 61120 R-GGA-5682588 https://reactome.org/PathwayBrowser/#/R-GGA-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Gallus gallus 61120 R-GGA-5682598 https://reactome.org/PathwayBrowser/#/R-GGA-5682598 ATM phosphorylates HERC2 IEA Gallus gallus 61120 R-GGA-5682607 https://reactome.org/PathwayBrowser/#/R-GGA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Gallus gallus 61120 R-GGA-5682629 https://reactome.org/PathwayBrowser/#/R-GGA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Gallus gallus 61120 R-GGA-5682858 https://reactome.org/PathwayBrowser/#/R-GGA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Gallus gallus 61120 R-GGA-5682863 https://reactome.org/PathwayBrowser/#/R-GGA-5682863 RNF168 binds DNA DSBs IEA Gallus gallus 61120 R-GGA-5682965 https://reactome.org/PathwayBrowser/#/R-GGA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Gallus gallus 61120 R-GGA-5682967 https://reactome.org/PathwayBrowser/#/R-GGA-5682967 WHSC1 binds DNA DSBs IEA Gallus gallus 61120 R-GGA-5682983 https://reactome.org/PathwayBrowser/#/R-GGA-5682983 ATM phosphorylates WHSC1 IEA Gallus gallus 61120 R-GGA-5682992 https://reactome.org/PathwayBrowser/#/R-GGA-5682992 KDM4A,B bind H4K20Me2 IEA Gallus gallus 61120 R-GGA-5683077 https://reactome.org/PathwayBrowser/#/R-GGA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Gallus gallus 61120 R-GGA-5683384 https://reactome.org/PathwayBrowser/#/R-GGA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Gallus gallus 61120 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus 61120 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus 61120 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus 61120 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus 61120 R-GGA-5683964 https://reactome.org/PathwayBrowser/#/R-GGA-5683964 ATM phosphorylates EYA1-4 IEA Gallus gallus 61120 R-GGA-5683967 https://reactome.org/PathwayBrowser/#/R-GGA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Gallus gallus 61120 R-GGA-5683986 https://reactome.org/PathwayBrowser/#/R-GGA-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA Gallus gallus 61120 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus 61120 R-GGA-5684081 https://reactome.org/PathwayBrowser/#/R-GGA-5684081 MRN complex binds CDK2 and RBBP8 IEA Gallus gallus 61120 R-GGA-5684096 https://reactome.org/PathwayBrowser/#/R-GGA-5684096 CDK2 phosphorylates RBBP8 IEA Gallus gallus 61120 R-GGA-5684108 https://reactome.org/PathwayBrowser/#/R-GGA-5684108 BRCA1 binds phosphorylated RBBP8 IEA Gallus gallus 61120 R-GGA-5684140 https://reactome.org/PathwayBrowser/#/R-GGA-5684140 ATM phosphorylates RBBP8 IEA Gallus gallus 61120 R-GGA-5684875 https://reactome.org/PathwayBrowser/#/R-GGA-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Gallus gallus 61120 R-GGA-5685011 https://reactome.org/PathwayBrowser/#/R-GGA-5685011 ATR activation at DNA DSBs IEA Gallus gallus 61120 R-GGA-5685156 https://reactome.org/PathwayBrowser/#/R-GGA-5685156 ATR phosphorylates RPA2 IEA Gallus gallus 61120 R-GGA-5685341 https://reactome.org/PathwayBrowser/#/R-GGA-5685341 BCDX2 complex stabilizes RAD51 filament IEA Gallus gallus 61120 R-GGA-5685838 https://reactome.org/PathwayBrowser/#/R-GGA-5685838 CX3 complex binds D-loop structures IEA Gallus gallus 61120 R-GGA-5685985 https://reactome.org/PathwayBrowser/#/R-GGA-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Gallus gallus 61120 R-GGA-5685994 https://reactome.org/PathwayBrowser/#/R-GGA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Gallus gallus 61120 R-GGA-5686642 https://reactome.org/PathwayBrowser/#/R-GGA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Gallus gallus 61120 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus 61120 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus 61120 R-GGA-5686900 https://reactome.org/PathwayBrowser/#/R-GGA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Gallus gallus 61120 R-GGA-5686924 https://reactome.org/PathwayBrowser/#/R-GGA-5686924 DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs IEA Gallus gallus 61120 R-GGA-5687183 https://reactome.org/PathwayBrowser/#/R-GGA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Gallus gallus 61120 R-GGA-5687360 https://reactome.org/PathwayBrowser/#/R-GGA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Gallus gallus 61120 R-GGA-5687464 https://reactome.org/PathwayBrowser/#/R-GGA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Gallus gallus 61120 R-GGA-5687465 https://reactome.org/PathwayBrowser/#/R-GGA-5687465 MRN complex binds RBBP8 IEA Gallus gallus 61120 R-GGA-5687484 https://reactome.org/PathwayBrowser/#/R-GGA-5687484 PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site IEA Gallus gallus 61120 R-GGA-5687640 https://reactome.org/PathwayBrowser/#/R-GGA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Gallus gallus 61120 R-GGA-5687653 https://reactome.org/PathwayBrowser/#/R-GGA-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Gallus gallus 61120 R-GGA-5687664 https://reactome.org/PathwayBrowser/#/R-GGA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Gallus gallus 61120 R-GGA-5687673 https://reactome.org/PathwayBrowser/#/R-GGA-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites IEA Gallus gallus 61120 R-GGA-5687675 https://reactome.org/PathwayBrowser/#/R-GGA-5687675 LIG3 ligates remaining SSBs in MMEJ IEA Gallus gallus 61120 R-GGA-5689317 https://reactome.org/PathwayBrowser/#/R-GGA-5689317 Formation of the pre-incision complex in GG-NER IEA Gallus gallus 61120 R-GGA-5689861 https://reactome.org/PathwayBrowser/#/R-GGA-5689861 Recruitment of XPA and release of CAK IEA Gallus gallus 61120 R-GGA-5690213 https://reactome.org/PathwayBrowser/#/R-GGA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Gallus gallus 61120 R-GGA-5690990 https://reactome.org/PathwayBrowser/#/R-GGA-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Gallus gallus 61120 R-GGA-5690996 https://reactome.org/PathwayBrowser/#/R-GGA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Gallus gallus 61120 R-GGA-5691000 https://reactome.org/PathwayBrowser/#/R-GGA-5691000 TFIIH binds GG-NER site to form a verification complex IEA Gallus gallus 61120 R-GGA-5691001 https://reactome.org/PathwayBrowser/#/R-GGA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Gallus gallus 61120 R-GGA-5691006 https://reactome.org/PathwayBrowser/#/R-GGA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Gallus gallus 61120 R-GGA-5693533 https://reactome.org/PathwayBrowser/#/R-GGA-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends IEA Gallus gallus 61120 R-GGA-5693536 https://reactome.org/PathwayBrowser/#/R-GGA-5693536 ATM phosphorylates MDC1 IEA Gallus gallus 61120 R-GGA-5693539 https://reactome.org/PathwayBrowser/#/R-GGA-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Gallus gallus 61120 R-GGA-5693540 https://reactome.org/PathwayBrowser/#/R-GGA-5693540 MRN activates ATM IEA Gallus gallus 61120 R-GGA-5693542 https://reactome.org/PathwayBrowser/#/R-GGA-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Gallus gallus 61120 R-GGA-5693549 https://reactome.org/PathwayBrowser/#/R-GGA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Gallus gallus 61120 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus 61120 R-GGA-5693564 https://reactome.org/PathwayBrowser/#/R-GGA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Gallus gallus 61120 R-GGA-5693566 https://reactome.org/PathwayBrowser/#/R-GGA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Gallus gallus 61120 R-GGA-5693574 https://reactome.org/PathwayBrowser/#/R-GGA-5693574 XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ IEA Gallus gallus 61120 R-GGA-5693575 https://reactome.org/PathwayBrowser/#/R-GGA-5693575 DNA-PKcs autophosphorylates IEA Gallus gallus 61120 R-GGA-5693578 https://reactome.org/PathwayBrowser/#/R-GGA-5693578 TDP1 and TDP2 process unligatable DSB ends IEA Gallus gallus 61120 R-GGA-5693580 https://reactome.org/PathwayBrowser/#/R-GGA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Gallus gallus 61120 R-GGA-5693584 https://reactome.org/PathwayBrowser/#/R-GGA-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Gallus gallus 61120 R-GGA-5693593 https://reactome.org/PathwayBrowser/#/R-GGA-5693593 D-loop extension by DNA polymerases IEA Gallus gallus 61120 R-GGA-5693598 https://reactome.org/PathwayBrowser/#/R-GGA-5693598 ATM phosphorylates NBN IEA Gallus gallus 61120 R-GGA-5693602 https://reactome.org/PathwayBrowser/#/R-GGA-5693602 ATM recognizes H2AFX-Nucleosomes IEA Gallus gallus 61120 R-GGA-5693608 https://reactome.org/PathwayBrowser/#/R-GGA-5693608 Initial resection of double-strand break ends IEA Gallus gallus 61120 R-GGA-5693612 https://reactome.org/PathwayBrowser/#/R-GGA-5693612 MRN complex bound to DNA ends recruits ATM IEA Gallus gallus 61120 R-GGA-5693615 https://reactome.org/PathwayBrowser/#/R-GGA-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis IEA Gallus gallus 61120 R-GGA-5693620 https://reactome.org/PathwayBrowser/#/R-GGA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Gallus gallus 61120 R-GGA-5696655 https://reactome.org/PathwayBrowser/#/R-GGA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Gallus gallus 61120 R-GGA-5696664 https://reactome.org/PathwayBrowser/#/R-GGA-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Gallus gallus 61120 R-GGA-5696670 https://reactome.org/PathwayBrowser/#/R-GGA-5696670 CHD1L is recruited to GG-NER site IEA Gallus gallus 61120 R-GGA-571316 https://reactome.org/PathwayBrowser/#/R-GGA-571316 Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. IEA Gallus gallus 61120 R-GGA-571318 https://reactome.org/PathwayBrowser/#/R-GGA-571318 Autoubiquitination of oligoTRAF6 bound to p-IRAK2 IEA Gallus gallus 61120 R-GGA-571324 https://reactome.org/PathwayBrowser/#/R-GGA-571324 IRAK2 binds to p-IRAK4:MyD88:activated TLR7 or 21 complex IEA Gallus gallus 61120 R-GGA-571327 https://reactome.org/PathwayBrowser/#/R-GGA-571327 IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex IEA Gallus gallus 61120 R-GGA-573294 https://reactome.org/PathwayBrowser/#/R-GGA-573294 Activated TRAF6 synthesizes free K63 linked pUb chains. IEA Gallus gallus 61120 R-GGA-573296 https://reactome.org/PathwayBrowser/#/R-GGA-573296 Activated TRAF6 recruits TAK1 kinase complex upon TLR7 or TLR21 stimulation IEA Gallus gallus 61120 R-GGA-6781818 https://reactome.org/PathwayBrowser/#/R-GGA-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Gallus gallus 61120 R-GGA-6781824 https://reactome.org/PathwayBrowser/#/R-GGA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Gallus gallus 61120 R-GGA-6781833 https://reactome.org/PathwayBrowser/#/R-GGA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Gallus gallus 61120 R-GGA-6781840 https://reactome.org/PathwayBrowser/#/R-GGA-6781840 ERCC6 binds stalled RNA Pol II IEA Gallus gallus 61120 R-GGA-6781867 https://reactome.org/PathwayBrowser/#/R-GGA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Gallus gallus 61120 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus 61120 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus 61120 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus 61120 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus 61120 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus 61120 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus 61120 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus 61120 R-GGA-6782943 https://reactome.org/PathwayBrowser/#/R-GGA-6782943 UV-DDB ubiquitinates XPC IEA Gallus gallus 61120 R-GGA-6790454 https://reactome.org/PathwayBrowser/#/R-GGA-6790454 SUMOylation of XPC IEA Gallus gallus 61120 R-GGA-6790487 https://reactome.org/PathwayBrowser/#/R-GGA-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Gallus gallus 61120 R-GGA-6792712 https://reactome.org/PathwayBrowser/#/R-GGA-6792712 KAT5 acetylates ATM at shortened telomeres IEA Gallus gallus 61120 R-GGA-68913 https://reactome.org/PathwayBrowser/#/R-GGA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Gallus gallus 61120 R-GGA-68914 https://reactome.org/PathwayBrowser/#/R-GGA-68914 DNA polymerase alpha:primase binds at the origin IEA Gallus gallus 61120 R-GGA-68944 https://reactome.org/PathwayBrowser/#/R-GGA-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Gallus gallus 61120 R-GGA-68950 https://reactome.org/PathwayBrowser/#/R-GGA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Gallus gallus 61120 R-GGA-68960 https://reactome.org/PathwayBrowser/#/R-GGA-68960 DNA polymerase epsilon binds at the origin IEA Gallus gallus 61120 R-GGA-69053 https://reactome.org/PathwayBrowser/#/R-GGA-69053 RFC binding displaces Pol Alpha IEA Gallus gallus 61120 R-GGA-69063 https://reactome.org/PathwayBrowser/#/R-GGA-69063 Loading of PCNA - Sliding Clamp Formation IEA Gallus gallus 61120 R-GGA-69068 https://reactome.org/PathwayBrowser/#/R-GGA-69068 RFC dissociates after sliding clamp formation IEA Gallus gallus 61120 R-GGA-69173 https://reactome.org/PathwayBrowser/#/R-GGA-69173 Joining of adjacent Okazaki fragments IEA Gallus gallus 61120 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus 61120 R-GGA-73718 https://reactome.org/PathwayBrowser/#/R-GGA-73718 UBF-1 Binds rDNA Promoter IEA Gallus gallus 61120 R-GGA-73739 https://reactome.org/PathwayBrowser/#/R-GGA-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Gallus gallus 61120 R-GGA-73758 https://reactome.org/PathwayBrowser/#/R-GGA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Gallus gallus 61120 R-GGA-73769 https://reactome.org/PathwayBrowser/#/R-GGA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Gallus gallus 61120 R-GGA-73946 https://reactome.org/PathwayBrowser/#/R-GGA-73946 Abortive initiation after formation of the first phosphodiester bond IEA Gallus gallus 61120 R-GGA-75095 https://reactome.org/PathwayBrowser/#/R-GGA-75095 Binding of TFIIE to the growing preinitiation complex IEA Gallus gallus 61120 R-GGA-75850 https://reactome.org/PathwayBrowser/#/R-GGA-75850 Addition of the third nucleotide on the nascent transcript IEA Gallus gallus 61120 R-GGA-75856 https://reactome.org/PathwayBrowser/#/R-GGA-75856 Abortive Initiation Before Second Transition IEA Gallus gallus 61120 R-GGA-75861 https://reactome.org/PathwayBrowser/#/R-GGA-75861 NTP Binds Active Site of RNA Polymerase II IEA Gallus gallus 61120 R-GGA-75862 https://reactome.org/PathwayBrowser/#/R-GGA-75862 Fall Back to Closed Pre-initiation Complex IEA Gallus gallus 61120 R-GGA-75864 https://reactome.org/PathwayBrowser/#/R-GGA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Gallus gallus 61120 R-GGA-75866 https://reactome.org/PathwayBrowser/#/R-GGA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Gallus gallus 61120 R-GGA-75869 https://reactome.org/PathwayBrowser/#/R-GGA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Gallus gallus 61120 R-GGA-75873 https://reactome.org/PathwayBrowser/#/R-GGA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Gallus gallus 61120 R-GGA-75891 https://reactome.org/PathwayBrowser/#/R-GGA-75891 Abortive Initiation After Second Transition IEA Gallus gallus 61120 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus 61120 R-GGA-76052 https://reactome.org/PathwayBrowser/#/R-GGA-76052 Binding of TFIIIA To type 1 Promoter IEA Gallus gallus 61120 R-GGA-76056 https://reactome.org/PathwayBrowser/#/R-GGA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Gallus gallus 61120 R-GGA-76576 https://reactome.org/PathwayBrowser/#/R-GGA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Gallus gallus 61120 R-GGA-77068 https://reactome.org/PathwayBrowser/#/R-GGA-77068 Activation of GT IEA Gallus gallus 61120 R-GGA-77069 https://reactome.org/PathwayBrowser/#/R-GGA-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Gallus gallus 61120 R-GGA-77071 https://reactome.org/PathwayBrowser/#/R-GGA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Gallus gallus 61120 R-GGA-77077 https://reactome.org/PathwayBrowser/#/R-GGA-77077 Capping complex formation IEA Gallus gallus 61120 R-GGA-77078 https://reactome.org/PathwayBrowser/#/R-GGA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Gallus gallus 61120 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus 61120 R-GGA-77083 https://reactome.org/PathwayBrowser/#/R-GGA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Gallus gallus 61120 R-GGA-77085 https://reactome.org/PathwayBrowser/#/R-GGA-77085 Dissociation of transcript with 5'-GMP from GT IEA Gallus gallus 61120 R-GGA-83791 https://reactome.org/PathwayBrowser/#/R-GGA-83791 Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter IEA Gallus gallus 61120 R-GGA-83793 https://reactome.org/PathwayBrowser/#/R-GGA-83793 Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex IEA Gallus gallus 61120 R-GGA-83803 https://reactome.org/PathwayBrowser/#/R-GGA-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Gallus gallus 61120 R-GGA-83805 https://reactome.org/PathwayBrowser/#/R-GGA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Gallus gallus 61120 R-GGA-9604487 https://reactome.org/PathwayBrowser/#/R-GGA-9604487 p-IRF7:p-IRF7 translocates to the nucleus IEA Gallus gallus 61120 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus 61120 R-GGA-9613497 https://reactome.org/PathwayBrowser/#/R-GGA-9613497 Unwinding DNA for the nascent transcript IEA Gallus gallus 61120 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus 61120 R-GGA-9734475 https://reactome.org/PathwayBrowser/#/R-GGA-9734475 PPARA binds fibrates IEA Gallus gallus 61120 R-GGA-994000 https://reactome.org/PathwayBrowser/#/R-GGA-994000 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation IEA Gallus gallus 61120 R-GGA-996727 https://reactome.org/PathwayBrowser/#/R-GGA-996727 REST recruits the BHC complex IEA Gallus gallus 61120 R-HSA-1008200 https://reactome.org/PathwayBrowser/#/R-HSA-1008200 NFE2 binds the beta globin locus control region TAS Homo sapiens 61120 R-HSA-1008220 https://reactome.org/PathwayBrowser/#/R-HSA-1008220 Expression of globin genes under control of the beta globin control region TAS Homo sapiens 61120 R-HSA-1031713 https://reactome.org/PathwayBrowser/#/R-HSA-1031713 GAF binds the GAS promoter elements in the IFNG-regulated genes TAS Homo sapiens 61120 R-HSA-1031716 https://reactome.org/PathwayBrowser/#/R-HSA-1031716 Expression of IFNG-stimulated genes TAS Homo sapiens 61120 R-HSA-109636 https://reactome.org/PathwayBrowser/#/R-HSA-109636 Recognition and Binding of Core Promoter Elements by TFIID TAS Homo sapiens 61120 R-HSA-109637 https://reactome.org/PathwayBrowser/#/R-HSA-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex TAS Homo sapiens 61120 R-HSA-109638 https://reactome.org/PathwayBrowser/#/R-HSA-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex TAS Homo sapiens 61120 R-HSA-109639 https://reactome.org/PathwayBrowser/#/R-HSA-109639 Formation of the closed pre-initiation complex TAS Homo sapiens 61120 R-HSA-109699 https://reactome.org/PathwayBrowser/#/R-HSA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 TAS Homo sapiens 61120 R-HSA-111264 https://reactome.org/PathwayBrowser/#/R-HSA-111264 Addition of nucleotides between position +11 and +30 TAS Homo sapiens 61120 R-HSA-112054 https://reactome.org/PathwayBrowser/#/R-HSA-112054 RNA Polymerase III Abortive Initiation At Type 3 Open Promoters IEA Homo sapiens 61120 R-HSA-112055 https://reactome.org/PathwayBrowser/#/R-HSA-112055 RNA Polymerase III Abortive Initiation At Type 1 Open Promoters IEA Homo sapiens 61120 R-HSA-112149 https://reactome.org/PathwayBrowser/#/R-HSA-112149 RNA Polymerase III Abortive Initiation At Type 2 Open Promoters IEA Homo sapiens 61120 R-HSA-112150 https://reactome.org/PathwayBrowser/#/R-HSA-112150 RNA Polymerase III Promoter Opening at Type 2 Promoters IEA Homo sapiens 61120 R-HSA-112152 https://reactome.org/PathwayBrowser/#/R-HSA-112152 RNA Polymerase III Promoter Opening at Type 3 Promoters IEA Homo sapiens 61120 R-HSA-112153 https://reactome.org/PathwayBrowser/#/R-HSA-112153 RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters IEA Homo sapiens 61120 R-HSA-112155 https://reactome.org/PathwayBrowser/#/R-HSA-112155 RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters IEA Homo sapiens 61120 R-HSA-112156 https://reactome.org/PathwayBrowser/#/R-HSA-112156 RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters IEA Homo sapiens 61120 R-HSA-112379 https://reactome.org/PathwayBrowser/#/R-HSA-112379 Recruitment of elongation factors to form elongation complex TAS Homo sapiens 61120 R-HSA-112381 https://reactome.org/PathwayBrowser/#/R-HSA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex TAS Homo sapiens 61120 R-HSA-112385 https://reactome.org/PathwayBrowser/#/R-HSA-112385 Addition of nucleotides leads to transcript elongation TAS Homo sapiens 61120 R-HSA-113429 https://reactome.org/PathwayBrowser/#/R-HSA-113429 Elongating transcript encounters a lesion in the template TAS Homo sapiens 61120 R-HSA-113430 https://reactome.org/PathwayBrowser/#/R-HSA-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex TAS Homo sapiens 61120 R-HSA-113442 https://reactome.org/PathwayBrowser/#/R-HSA-113442 RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites IEA Homo sapiens 61120 R-HSA-113446 https://reactome.org/PathwayBrowser/#/R-HSA-113446 Initiation of RNA Polymerase III Productive Transcription IEA Homo sapiens 61120 R-HSA-113449 https://reactome.org/PathwayBrowser/#/R-HSA-113449 RNA Polymerase III Transcriptional Pause at Terminator Sequence IEA Homo sapiens 61120 R-HSA-113451 https://reactome.org/PathwayBrowser/#/R-HSA-113451 Resumption of RNA Polymerase III Productive Transcription IEA Homo sapiens 61120 R-HSA-113454 https://reactome.org/PathwayBrowser/#/R-HSA-113454 RNA Polymerase III Termination and release of transcribed RNA IEA Homo sapiens 61120 R-HSA-113503 https://reactome.org/PathwayBrowser/#/R-HSA-113503 PP2A mediated localization of RB1 protein in chromatin TAS Homo sapiens 61120 R-HSA-113504 https://reactome.org/PathwayBrowser/#/R-HSA-113504 Detection of damage during initiation of DNA synthesis in S-phase TAS Homo sapiens 61120 R-HSA-113638 https://reactome.org/PathwayBrowser/#/R-HSA-113638 Association of Cyclin B/Cdk1 with replicative origin inhibits pre-RC formation IEA Homo sapiens 61120 R-HSA-113643 https://reactome.org/PathwayBrowser/#/R-HSA-113643 Replication initiation regulation by Rb1/E2F1 IEA Homo sapiens 61120 R-HSA-113705 https://reactome.org/PathwayBrowser/#/R-HSA-113705 RNA Polymerase III Productive Transcription IEA Homo sapiens 61120 R-HSA-1225919 https://reactome.org/PathwayBrowser/#/R-HSA-1225919 Phospho R-SMAD(SMAD2,3):CO-SMAD(SMAD4):FOXH1 binds Activin Response Element IEA Homo sapiens 61120 R-HSA-1368065 https://reactome.org/PathwayBrowser/#/R-HSA-1368065 Expression of NPAS2 IEA Homo sapiens 61120 R-HSA-1535903 https://reactome.org/PathwayBrowser/#/R-HSA-1535903 Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements TAS Homo sapiens 61120 R-HSA-1592238 https://reactome.org/PathwayBrowser/#/R-HSA-1592238 Expression of ALAS1 TAS Homo sapiens 61120 R-HSA-163296 https://reactome.org/PathwayBrowser/#/R-HSA-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M TAS Homo sapiens 61120 R-HSA-163310 https://reactome.org/PathwayBrowser/#/R-HSA-163310 TFAM binds to mitochondrial promoters TAS Homo sapiens 61120 R-HSA-163320 https://reactome.org/PathwayBrowser/#/R-HSA-163320 Association of mTERF with the termination sequence TAS Homo sapiens 61120 R-HSA-1655826 https://reactome.org/PathwayBrowser/#/R-HSA-1655826 Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) TAS Homo sapiens 61120 R-HSA-1655848 https://reactome.org/PathwayBrowser/#/R-HSA-1655848 Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) TAS Homo sapiens 61120 R-HSA-1655850 https://reactome.org/PathwayBrowser/#/R-HSA-1655850 Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) TAS Homo sapiens 61120 R-HSA-167098 https://reactome.org/PathwayBrowser/#/R-HSA-167098 Phosphorylation (Ser5) of RNA pol II CTD IEA Homo sapiens 61120 R-HSA-1679098 https://reactome.org/PathwayBrowser/#/R-HSA-1679098 Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer TAS Homo sapiens 61120 R-HSA-1679589 https://reactome.org/PathwayBrowser/#/R-HSA-1679589 Engulfed CpG DNA binds to endosomal full-length TLR9 TAS Homo sapiens 61120 R-HSA-169461 https://reactome.org/PathwayBrowser/#/R-HSA-169461 MCM8 mediated fork unwinding IEA Homo sapiens 61120 R-HSA-169468 https://reactome.org/PathwayBrowser/#/R-HSA-169468 MCM2-7 mediated fork unwinding IEA Homo sapiens 61120 R-HSA-174427 https://reactome.org/PathwayBrowser/#/R-HSA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere TAS Homo sapiens 61120 R-HSA-174438 https://reactome.org/PathwayBrowser/#/R-HSA-174438 Formation of the Flap Intermediate on the C-strand TAS Homo sapiens 61120 R-HSA-174439 https://reactome.org/PathwayBrowser/#/R-HSA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere TAS Homo sapiens 61120 R-HSA-174441 https://reactome.org/PathwayBrowser/#/R-HSA-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand TAS Homo sapiens 61120 R-HSA-174444 https://reactome.org/PathwayBrowser/#/R-HSA-174444 Formation of C-strand Okazaki fragments TAS Homo sapiens 61120 R-HSA-174445 https://reactome.org/PathwayBrowser/#/R-HSA-174445 RPA binds to the Flap on the C-strand TAS Homo sapiens 61120 R-HSA-174446 https://reactome.org/PathwayBrowser/#/R-HSA-174446 Removal of remaining Flap from the C-strand TAS Homo sapiens 61120 R-HSA-174447 https://reactome.org/PathwayBrowser/#/R-HSA-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere TAS Homo sapiens 61120 R-HSA-174448 https://reactome.org/PathwayBrowser/#/R-HSA-174448 Formation of Processive Complex on the C-strand of the telomere TAS Homo sapiens 61120 R-HSA-174451 https://reactome.org/PathwayBrowser/#/R-HSA-174451 Recruitment of DNA2 endonuclease to the C strand TAS Homo sapiens 61120 R-HSA-174452 https://reactome.org/PathwayBrowser/#/R-HSA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere TAS Homo sapiens 61120 R-HSA-174456 https://reactome.org/PathwayBrowser/#/R-HSA-174456 Joining of adjacent Okazaki fragments of the C-strand TAS Homo sapiens 61120 R-HSA-176101 https://reactome.org/PathwayBrowser/#/R-HSA-176101 Recruitment of Rad17-RFC complex to DNA TAS Homo sapiens 61120 R-HSA-176175 https://reactome.org/PathwayBrowser/#/R-HSA-176175 Stalling of DNA replication fork and RPA binding TAS Homo sapiens 61120 R-HSA-176250 https://reactome.org/PathwayBrowser/#/R-HSA-176250 Binding of ATR-ATRIP to the RPA-ssDNA complex TAS Homo sapiens 61120 R-HSA-176264 https://reactome.org/PathwayBrowser/#/R-HSA-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA TAS Homo sapiens 61120 R-HSA-176298 https://reactome.org/PathwayBrowser/#/R-HSA-176298 Activation of claspin TAS Homo sapiens 61120 R-HSA-176318 https://reactome.org/PathwayBrowser/#/R-HSA-176318 Loading of claspin onto DNA during replication origin firing TAS Homo sapiens 61120 R-HSA-176942 https://reactome.org/PathwayBrowser/#/R-HSA-176942 Multiple proteins are localized at replication fork IEA Homo sapiens 61120 R-HSA-1801587 https://reactome.org/PathwayBrowser/#/R-HSA-1801587 Expression of CPT1A IEA Homo sapiens 61120 R-HSA-187895 https://reactome.org/PathwayBrowser/#/R-HSA-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 TAS Homo sapiens 61120 R-HSA-188002 https://reactome.org/PathwayBrowser/#/R-HSA-188002 Rab5-mediated recruitment of class III PI3K to TLR9 TAS Homo sapiens 61120 R-HSA-1989745 https://reactome.org/PathwayBrowser/#/R-HSA-1989745 Expression of ACADM TAS Homo sapiens 61120 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 61120 R-HSA-1989747 https://reactome.org/PathwayBrowser/#/R-HSA-1989747 Expression of FHL2 TAS Homo sapiens 61120 R-HSA-1989748 https://reactome.org/PathwayBrowser/#/R-HSA-1989748 Expression of GRHL1 TAS Homo sapiens 61120 R-HSA-1989749 https://reactome.org/PathwayBrowser/#/R-HSA-1989749 Expression of ACOX1 TAS Homo sapiens 61120 R-HSA-1989750 https://reactome.org/PathwayBrowser/#/R-HSA-1989750 Expression of FATP1 (SLC27A1) TAS Homo sapiens 61120 R-HSA-1989751 https://reactome.org/PathwayBrowser/#/R-HSA-1989751 Expression of FABP1 TAS Homo sapiens 61120 R-HSA-1989752 https://reactome.org/PathwayBrowser/#/R-HSA-1989752 Expression of TXNRD1 TAS Homo sapiens 61120 R-HSA-1989753 https://reactome.org/PathwayBrowser/#/R-HSA-1989753 Expression of PEX11A TAS Homo sapiens 61120 R-HSA-1989754 https://reactome.org/PathwayBrowser/#/R-HSA-1989754 Expression of APOA1 TAS Homo sapiens 61120 R-HSA-1989755 https://reactome.org/PathwayBrowser/#/R-HSA-1989755 Expression of CYP4A11 TAS Homo sapiens 61120 R-HSA-1989756 https://reactome.org/PathwayBrowser/#/R-HSA-1989756 Expression of ME1 TAS Homo sapiens 61120 R-HSA-1989757 https://reactome.org/PathwayBrowser/#/R-HSA-1989757 Expression of FADS1 TAS Homo sapiens 61120 R-HSA-1989758 https://reactome.org/PathwayBrowser/#/R-HSA-1989758 Expression of UGT1A9 TAS Homo sapiens 61120 R-HSA-1989759 https://reactome.org/PathwayBrowser/#/R-HSA-1989759 Expression of G0S2 TAS Homo sapiens 61120 R-HSA-1989760 https://reactome.org/PathwayBrowser/#/R-HSA-1989760 Expression of HMGCS2 TAS Homo sapiens 61120 R-HSA-1989761 https://reactome.org/PathwayBrowser/#/R-HSA-1989761 Expression of APOA5 TAS Homo sapiens 61120 R-HSA-1989762 https://reactome.org/PathwayBrowser/#/R-HSA-1989762 Expression of ABCB4 TAS Homo sapiens 61120 R-HSA-1989764 https://reactome.org/PathwayBrowser/#/R-HSA-1989764 Expression of CYP1A1 TAS Homo sapiens 61120 R-HSA-1989765 https://reactome.org/PathwayBrowser/#/R-HSA-1989765 Expression of ABCA1 TAS Homo sapiens 61120 R-HSA-1989767 https://reactome.org/PathwayBrowser/#/R-HSA-1989767 Expression of TRIB3 TAS Homo sapiens 61120 R-HSA-1989768 https://reactome.org/PathwayBrowser/#/R-HSA-1989768 Expression of TIAM2 TAS Homo sapiens 61120 R-HSA-1989770 https://reactome.org/PathwayBrowser/#/R-HSA-1989770 Expression of PLIN2 TAS Homo sapiens 61120 R-HSA-1989771 https://reactome.org/PathwayBrowser/#/R-HSA-1989771 Expression of TNFRSF21 TAS Homo sapiens 61120 R-HSA-1989772 https://reactome.org/PathwayBrowser/#/R-HSA-1989772 Expression of GLIPR1 TAS Homo sapiens 61120 R-HSA-1989773 https://reactome.org/PathwayBrowser/#/R-HSA-1989773 Expression of CPT2 TAS Homo sapiens 61120 R-HSA-1989774 https://reactome.org/PathwayBrowser/#/R-HSA-1989774 Expression of AGT TAS Homo sapiens 61120 R-HSA-1989775 https://reactome.org/PathwayBrowser/#/R-HSA-1989775 Expression of SULT2A1 TAS Homo sapiens 61120 R-HSA-1989776 https://reactome.org/PathwayBrowser/#/R-HSA-1989776 Expression of APOA2 TAS Homo sapiens 61120 R-HSA-1989777 https://reactome.org/PathwayBrowser/#/R-HSA-1989777 Expression of RGL1 TAS Homo sapiens 61120 R-HSA-1989778 https://reactome.org/PathwayBrowser/#/R-HSA-1989778 Expression of ACSL1 TAS Homo sapiens 61120 R-HSA-1989779 https://reactome.org/PathwayBrowser/#/R-HSA-1989779 Expression of ANKRD1 TAS Homo sapiens 61120 R-HSA-211247 https://reactome.org/PathwayBrowser/#/R-HSA-211247 Cleavage of DNA by DFF40 TAS Homo sapiens 61120 R-HSA-2173781 https://reactome.org/PathwayBrowser/#/R-HSA-2173781 MARCO (SCARA2) binds ligands IEA Homo sapiens 61120 R-HSA-2247510 https://reactome.org/PathwayBrowser/#/R-HSA-2247510 MARCO:ligand is endocytosed TAS Homo sapiens 61120 R-HSA-3134883 https://reactome.org/PathwayBrowser/#/R-HSA-3134883 Beta-catenin enhances association of IRF3 with CBP/p300 TAS Homo sapiens 61120 R-HSA-3134953 https://reactome.org/PathwayBrowser/#/R-HSA-3134953 DHX36 or DHX9 binds MyD88 TAS Homo sapiens 61120 R-HSA-3134954 https://reactome.org/PathwayBrowser/#/R-HSA-3134954 DHX9 binds DNA TAS Homo sapiens 61120 R-HSA-3134962 https://reactome.org/PathwayBrowser/#/R-HSA-3134962 DHX36 binds DNA TAS Homo sapiens 61120 R-HSA-3785704 https://reactome.org/PathwayBrowser/#/R-HSA-3785704 DSB inducing agents induce double strand DNA breaks TAS Homo sapiens 61120 R-HSA-3785711 https://reactome.org/PathwayBrowser/#/R-HSA-3785711 Telomere shortening during replicative exhaustion TAS Homo sapiens 61120 R-HSA-3785768 https://reactome.org/PathwayBrowser/#/R-HSA-3785768 MRN complex binds DNA double strand breaks TAS Homo sapiens 61120 R-HSA-400143 https://reactome.org/PathwayBrowser/#/R-HSA-400143 Fatty acid ligands activate PPARA TAS Homo sapiens 61120 R-HSA-400183 https://reactome.org/PathwayBrowser/#/R-HSA-400183 PPARA:RXRA binds Corepressors of PPARA TAS Homo sapiens 61120 R-HSA-400204 https://reactome.org/PathwayBrowser/#/R-HSA-400204 PPARA binds RXRA TAS Homo sapiens 61120 R-HSA-5250930 https://reactome.org/PathwayBrowser/#/R-HSA-5250930 B-WICH recruits histone acetyltransferases TAS Homo sapiens 61120 R-HSA-5250938 https://reactome.org/PathwayBrowser/#/R-HSA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 TAS Homo sapiens 61120 R-HSA-5250947 https://reactome.org/PathwayBrowser/#/R-HSA-5250947 B-WICH complex binds rDNA promoter TAS Homo sapiens 61120 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 61120 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 61120 R-HSA-5682018 https://reactome.org/PathwayBrowser/#/R-HSA-5682018 MRN complex bound to shortened telomeres recruits ATM TAS Homo sapiens 61120 R-HSA-5682020 https://reactome.org/PathwayBrowser/#/R-HSA-5682020 MRN complex binds shortened telomeres TAS Homo sapiens 61120 R-HSA-5682026 https://reactome.org/PathwayBrowser/#/R-HSA-5682026 MRN bound to shortened telomeres activates ATM TAS Homo sapiens 61120 R-HSA-5682044 https://reactome.org/PathwayBrowser/#/R-HSA-5682044 KAT5 acetylates ATM at DNA DSBs TAS Homo sapiens 61120 R-HSA-5682586 https://reactome.org/PathwayBrowser/#/R-HSA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs TAS Homo sapiens 61120 R-HSA-5682588 https://reactome.org/PathwayBrowser/#/R-HSA-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs TAS Homo sapiens 61120 R-HSA-5682598 https://reactome.org/PathwayBrowser/#/R-HSA-5682598 ATM phosphorylates HERC2 TAS Homo sapiens 61120 R-HSA-5682607 https://reactome.org/PathwayBrowser/#/R-HSA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs TAS Homo sapiens 61120 R-HSA-5682629 https://reactome.org/PathwayBrowser/#/R-HSA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 TAS Homo sapiens 61120 R-HSA-5682858 https://reactome.org/PathwayBrowser/#/R-HSA-5682858 RNF8 and RNF168 ubiquitinate H2AFX TAS Homo sapiens 61120 R-HSA-5682863 https://reactome.org/PathwayBrowser/#/R-HSA-5682863 RNF168 binds DNA DSBs TAS Homo sapiens 61120 R-HSA-5682965 https://reactome.org/PathwayBrowser/#/R-HSA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs TAS Homo sapiens 61120 R-HSA-5682967 https://reactome.org/PathwayBrowser/#/R-HSA-5682967 WHSC1 binds DNA DSBs TAS Homo sapiens 61120 R-HSA-5682983 https://reactome.org/PathwayBrowser/#/R-HSA-5682983 ATM phosphorylates WHSC1 TAS Homo sapiens 61120 R-HSA-5682992 https://reactome.org/PathwayBrowser/#/R-HSA-5682992 KDM4A,B bind H4K20Me2 TAS Homo sapiens 61120 R-HSA-5683077 https://reactome.org/PathwayBrowser/#/R-HSA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B TAS Homo sapiens 61120 R-HSA-5683384 https://reactome.org/PathwayBrowser/#/R-HSA-5683384 UIMC1 and FAM175A bind DNA DSBs TAS Homo sapiens 61120 R-HSA-5683385 https://reactome.org/PathwayBrowser/#/R-HSA-5683385 Formation of BRCA1-A complex at DNA DSBs TAS Homo sapiens 61120 R-HSA-5683405 https://reactome.org/PathwayBrowser/#/R-HSA-5683405 PPP5C dephosphorylates TP53BP1 TAS Homo sapiens 61120 R-HSA-5683425 https://reactome.org/PathwayBrowser/#/R-HSA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs TAS Homo sapiens 61120 R-HSA-5683735 https://reactome.org/PathwayBrowser/#/R-HSA-5683735 CHEK2 is recruited to DNA DSBs TAS Homo sapiens 61120 R-HSA-5683801 https://reactome.org/PathwayBrowser/#/R-HSA-5683801 CHEK2 phosphorylates BRCA1 TAS Homo sapiens 61120 R-HSA-5683964 https://reactome.org/PathwayBrowser/#/R-HSA-5683964 ATM phosphorylates EYA1-4 TAS Homo sapiens 61120 R-HSA-5683967 https://reactome.org/PathwayBrowser/#/R-HSA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX TAS Homo sapiens 61120 R-HSA-5683986 https://reactome.org/PathwayBrowser/#/R-HSA-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX TAS Homo sapiens 61120 R-HSA-5684052 https://reactome.org/PathwayBrowser/#/R-HSA-5684052 PIAS4 SUMOylates MDC1 TAS Homo sapiens 61120 R-HSA-5684071 https://reactome.org/PathwayBrowser/#/R-HSA-5684071 RNF4 ubiquitinates MDC1 TAS Homo sapiens 61120 R-HSA-5684081 https://reactome.org/PathwayBrowser/#/R-HSA-5684081 MRN complex binds CDK2 and RBBP8 TAS Homo sapiens 61120 R-HSA-5684096 https://reactome.org/PathwayBrowser/#/R-HSA-5684096 CDK2 phosphorylates RBBP8 TAS Homo sapiens 61120 R-HSA-5684108 https://reactome.org/PathwayBrowser/#/R-HSA-5684108 BRCA1 binds phosphorylated RBBP8 TAS Homo sapiens 61120 R-HSA-5684140 https://reactome.org/PathwayBrowser/#/R-HSA-5684140 ATM phosphorylates RBBP8 TAS Homo sapiens 61120 R-HSA-5684875 https://reactome.org/PathwayBrowser/#/R-HSA-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs TAS Homo sapiens 61120 R-HSA-5684882 https://reactome.org/PathwayBrowser/#/R-HSA-5684882 CHEK1 is recruited to resected DNA DSBs TAS Homo sapiens 61120 R-HSA-5684887 https://reactome.org/PathwayBrowser/#/R-HSA-5684887 Activation of CHEK1 at resected DNA DSBs TAS Homo sapiens 61120 R-HSA-5685011 https://reactome.org/PathwayBrowser/#/R-HSA-5685011 ATR activation at DNA DSBs TAS Homo sapiens 61120 R-HSA-5685156 https://reactome.org/PathwayBrowser/#/R-HSA-5685156 ATR phosphorylates RPA2 TAS Homo sapiens 61120 R-HSA-5685341 https://reactome.org/PathwayBrowser/#/R-HSA-5685341 BCDX2 complex stabilizes RAD51 filament TAS Homo sapiens 61120 R-HSA-5685838 https://reactome.org/PathwayBrowser/#/R-HSA-5685838 CX3 complex binds D-loop structures TAS Homo sapiens 61120 R-HSA-5685985 https://reactome.org/PathwayBrowser/#/R-HSA-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment TAS Homo sapiens 61120 R-HSA-5685994 https://reactome.org/PathwayBrowser/#/R-HSA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 TAS Homo sapiens 61120 R-HSA-5686410 https://reactome.org/PathwayBrowser/#/R-HSA-5686410 BLM mediates dissolution of double Holliday junction TAS Homo sapiens 61120 R-HSA-5686440 https://reactome.org/PathwayBrowser/#/R-HSA-5686440 MUS81:EME1,EME2 cleaves D-loop TAS Homo sapiens 61120 R-HSA-5686469 https://reactome.org/PathwayBrowser/#/R-HSA-5686469 Resolution of D-loops cleaved by MUS81:EME1 or MUS81:EME2 TAS Homo sapiens 61120 R-HSA-5686483 https://reactome.org/PathwayBrowser/#/R-HSA-5686483 Resolution of Holliday junctions cleaved by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) TAS Homo sapiens 61120 R-HSA-5686642 https://reactome.org/PathwayBrowser/#/R-HSA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs TAS Homo sapiens 61120 R-HSA-5686657 https://reactome.org/PathwayBrowser/#/R-HSA-5686657 ERCC1:XPF cleaves flaps generated by SSA TAS Homo sapiens 61120 R-HSA-5686663 https://reactome.org/PathwayBrowser/#/R-HSA-5686663 Completion of SSA TAS Homo sapiens 61120 R-HSA-5686685 https://reactome.org/PathwayBrowser/#/R-HSA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs TAS Homo sapiens 61120 R-HSA-5686704 https://reactome.org/PathwayBrowser/#/R-HSA-5686704 Activated ATM phosphorylates DCLRE1C TAS Homo sapiens 61120 R-HSA-5686900 https://reactome.org/PathwayBrowser/#/R-HSA-5686900 TP53BP1 recruits DCLRE1C to ATM TAS Homo sapiens 61120 R-HSA-5686924 https://reactome.org/PathwayBrowser/#/R-HSA-5686924 DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs TAS Homo sapiens 61120 R-HSA-5687183 https://reactome.org/PathwayBrowser/#/R-HSA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs TAS Homo sapiens 61120 R-HSA-5687360 https://reactome.org/PathwayBrowser/#/R-HSA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps TAS Homo sapiens 61120 R-HSA-5687464 https://reactome.org/PathwayBrowser/#/R-HSA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ TAS Homo sapiens 61120 R-HSA-5687465 https://reactome.org/PathwayBrowser/#/R-HSA-5687465 MRN complex binds RBBP8 TAS Homo sapiens 61120 R-HSA-5687484 https://reactome.org/PathwayBrowser/#/R-HSA-5687484 PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site TAS Homo sapiens 61120 R-HSA-5687640 https://reactome.org/PathwayBrowser/#/R-HSA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ TAS Homo sapiens 61120 R-HSA-5687653 https://reactome.org/PathwayBrowser/#/R-HSA-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate TAS Homo sapiens 61120 R-HSA-5687664 https://reactome.org/PathwayBrowser/#/R-HSA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ TAS Homo sapiens 61120 R-HSA-5687673 https://reactome.org/PathwayBrowser/#/R-HSA-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites TAS Homo sapiens 61120 R-HSA-5687675 https://reactome.org/PathwayBrowser/#/R-HSA-5687675 LIG3 ligates remaining SSBs in MMEJ TAS Homo sapiens 61120 R-HSA-5689317 https://reactome.org/PathwayBrowser/#/R-HSA-5689317 Formation of the pre-incision complex in GG-NER TAS Homo sapiens 61120 R-HSA-5689861 https://reactome.org/PathwayBrowser/#/R-HSA-5689861 Recruitment of XPA and release of CAK TAS Homo sapiens 61120 R-HSA-5690213 https://reactome.org/PathwayBrowser/#/R-HSA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site TAS Homo sapiens 61120 R-HSA-5690988 https://reactome.org/PathwayBrowser/#/R-HSA-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER TAS Homo sapiens 61120 R-HSA-5690990 https://reactome.org/PathwayBrowser/#/R-HSA-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER TAS Homo sapiens 61120 R-HSA-5690991 https://reactome.org/PathwayBrowser/#/R-HSA-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER TAS Homo sapiens 61120 R-HSA-5690996 https://reactome.org/PathwayBrowser/#/R-HSA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA TAS Homo sapiens 61120 R-HSA-5691000 https://reactome.org/PathwayBrowser/#/R-HSA-5691000 TFIIH binds GG-NER site to form a verification complex TAS Homo sapiens 61120 R-HSA-5691001 https://reactome.org/PathwayBrowser/#/R-HSA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER TAS Homo sapiens 61120 R-HSA-5691006 https://reactome.org/PathwayBrowser/#/R-HSA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site TAS Homo sapiens 61120 R-HSA-5693533 https://reactome.org/PathwayBrowser/#/R-HSA-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends TAS Homo sapiens 61120 R-HSA-5693536 https://reactome.org/PathwayBrowser/#/R-HSA-5693536 ATM phosphorylates MDC1 TAS Homo sapiens 61120 R-HSA-5693539 https://reactome.org/PathwayBrowser/#/R-HSA-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis TAS Homo sapiens 61120 R-HSA-5693540 https://reactome.org/PathwayBrowser/#/R-HSA-5693540 MRN activates ATM TAS Homo sapiens 61120 R-HSA-5693542 https://reactome.org/PathwayBrowser/#/R-HSA-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs TAS Homo sapiens 61120 R-HSA-5693549 https://reactome.org/PathwayBrowser/#/R-HSA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs TAS Homo sapiens 61120 R-HSA-5693551 https://reactome.org/PathwayBrowser/#/R-HSA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM TAS Homo sapiens 61120 R-HSA-5693558 https://reactome.org/PathwayBrowser/#/R-HSA-5693558 Gap-filling DNA synthesis in SDSA TAS Homo sapiens 61120 R-HSA-5693561 https://reactome.org/PathwayBrowser/#/R-HSA-5693561 RAD51 binds BRCA2 at resected DNA DSBs TAS Homo sapiens 61120 R-HSA-5693564 https://reactome.org/PathwayBrowser/#/R-HSA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends TAS Homo sapiens 61120 R-HSA-5693566 https://reactome.org/PathwayBrowser/#/R-HSA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs TAS Homo sapiens 61120 R-HSA-5693574 https://reactome.org/PathwayBrowser/#/R-HSA-5693574 XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ TAS Homo sapiens 61120 R-HSA-5693575 https://reactome.org/PathwayBrowser/#/R-HSA-5693575 DNA-PKcs autophosphorylates TAS Homo sapiens 61120 R-HSA-5693578 https://reactome.org/PathwayBrowser/#/R-HSA-5693578 TDP1 and TDP2 process unligatable DSB ends TAS Homo sapiens 61120 R-HSA-5693580 https://reactome.org/PathwayBrowser/#/R-HSA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs TAS Homo sapiens 61120 R-HSA-5693583 https://reactome.org/PathwayBrowser/#/R-HSA-5693583 MDC1 associates with gamma-H2AFX at nuclear foci TAS Homo sapiens 61120 R-HSA-5693584 https://reactome.org/PathwayBrowser/#/R-HSA-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) TAS Homo sapiens 61120 R-HSA-5693589 https://reactome.org/PathwayBrowser/#/R-HSA-5693589 D-loop dissociation and strand annealing TAS Homo sapiens 61120 R-HSA-5693593 https://reactome.org/PathwayBrowser/#/R-HSA-5693593 D-loop extension by DNA polymerases TAS Homo sapiens 61120 R-HSA-5693598 https://reactome.org/PathwayBrowser/#/R-HSA-5693598 ATM phosphorylates NBN TAS Homo sapiens 61120 R-HSA-5693599 https://reactome.org/PathwayBrowser/#/R-HSA-5693599 Association of Ku heterodimer with ends of DNA double-strand break TAS Homo sapiens 61120 R-HSA-5693602 https://reactome.org/PathwayBrowser/#/R-HSA-5693602 ATM recognizes H2AFX-Nucleosomes TAS Homo sapiens 61120 R-HSA-5693604 https://reactome.org/PathwayBrowser/#/R-HSA-5693604 XRCC4:LIG4 ligates DNA DSB ends during NHEJ TAS Homo sapiens 61120 R-HSA-5693608 https://reactome.org/PathwayBrowser/#/R-HSA-5693608 Initial resection of double-strand break ends TAS Homo sapiens 61120 R-HSA-5693612 https://reactome.org/PathwayBrowser/#/R-HSA-5693612 MRN complex bound to DNA ends recruits ATM TAS Homo sapiens 61120 R-HSA-5693615 https://reactome.org/PathwayBrowser/#/R-HSA-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis TAS Homo sapiens 61120 R-HSA-5693620 https://reactome.org/PathwayBrowser/#/R-HSA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 TAS Homo sapiens 61120 R-HSA-5696655 https://reactome.org/PathwayBrowser/#/R-HSA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates TAS Homo sapiens 61120 R-HSA-5696664 https://reactome.org/PathwayBrowser/#/R-HSA-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site TAS Homo sapiens 61120 R-HSA-5696670 https://reactome.org/PathwayBrowser/#/R-HSA-5696670 CHD1L is recruited to GG-NER site TAS Homo sapiens 61120 R-HSA-6781818 https://reactome.org/PathwayBrowser/#/R-HSA-6781818 RNA Pol II initiates transcription from damaged DNA template TAS Homo sapiens 61120 R-HSA-6781824 https://reactome.org/PathwayBrowser/#/R-HSA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template TAS Homo sapiens 61120 R-HSA-6781833 https://reactome.org/PathwayBrowser/#/R-HSA-6781833 ERCC8 (CSA) binds stalled RNA Pol II TAS Homo sapiens 61120 R-HSA-6781840 https://reactome.org/PathwayBrowser/#/R-HSA-6781840 ERCC6 binds stalled RNA Pol II TAS Homo sapiens 61120 R-HSA-6781867 https://reactome.org/PathwayBrowser/#/R-HSA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II TAS Homo sapiens 61120 R-HSA-6782004 https://reactome.org/PathwayBrowser/#/R-HSA-6782004 Assembly of the pre-incision complex in TC-NER TAS Homo sapiens 61120 R-HSA-6782069 https://reactome.org/PathwayBrowser/#/R-HSA-6782069 UVSSA:USP7 deubiquitinates ERCC6 TAS Homo sapiens 61120 R-HSA-6782131 https://reactome.org/PathwayBrowser/#/R-HSA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER TAS Homo sapiens 61120 R-HSA-6782138 https://reactome.org/PathwayBrowser/#/R-HSA-6782138 ERCC5 and RPA bind TC-NER site TAS Homo sapiens 61120 R-HSA-6782141 https://reactome.org/PathwayBrowser/#/R-HSA-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER TAS Homo sapiens 61120 R-HSA-6782204 https://reactome.org/PathwayBrowser/#/R-HSA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER TAS Homo sapiens 61120 R-HSA-6782208 https://reactome.org/PathwayBrowser/#/R-HSA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER TAS Homo sapiens 61120 R-HSA-6782211 https://reactome.org/PathwayBrowser/#/R-HSA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site TAS Homo sapiens 61120 R-HSA-6782224 https://reactome.org/PathwayBrowser/#/R-HSA-6782224 3' incision by ERCC5 (XPG) in TC-NER TAS Homo sapiens 61120 R-HSA-6782227 https://reactome.org/PathwayBrowser/#/R-HSA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER TAS Homo sapiens 61120 R-HSA-6782234 https://reactome.org/PathwayBrowser/#/R-HSA-6782234 Recovery of RNA synthesis after TC-NER TAS Homo sapiens 61120 R-HSA-6782943 https://reactome.org/PathwayBrowser/#/R-HSA-6782943 UV-DDB ubiquitinates XPC TAS Homo sapiens 61120 R-HSA-6786166 https://reactome.org/PathwayBrowser/#/R-HSA-6786166 Translesion synthesis across unhooked ICL by POLN TAS Homo sapiens 61120 R-HSA-6790454 https://reactome.org/PathwayBrowser/#/R-HSA-6790454 SUMOylation of XPC TAS Homo sapiens 61120 R-HSA-6790487 https://reactome.org/PathwayBrowser/#/R-HSA-6790487 RNF111 ubiquitinates SUMOylated XPC TAS Homo sapiens 61120 R-HSA-6792712 https://reactome.org/PathwayBrowser/#/R-HSA-6792712 KAT5 acetylates ATM at shortened telomeres TAS Homo sapiens 61120 R-HSA-6799332 https://reactome.org/PathwayBrowser/#/R-HSA-6799332 ATR phosphorylates TP53 TAS Homo sapiens 61120 R-HSA-68611 https://reactome.org/PathwayBrowser/#/R-HSA-68611 Formation of ORC(1-5) complex TAS Homo sapiens 61120 R-HSA-68615 https://reactome.org/PathwayBrowser/#/R-HSA-68615 Formation of ORC(1-6) complex TAS Homo sapiens 61120 R-HSA-68688 https://reactome.org/PathwayBrowser/#/R-HSA-68688 CDC6 association with ORC(1-6) at replication origins TAS Homo sapiens 61120 R-HSA-68913 https://reactome.org/PathwayBrowser/#/R-HSA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin TAS Homo sapiens 61120 R-HSA-68914 https://reactome.org/PathwayBrowser/#/R-HSA-68914 DNA polymerase alpha:primase binds at the origin TAS Homo sapiens 61120 R-HSA-68916 https://reactome.org/PathwayBrowser/#/R-HSA-68916 DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin TAS Homo sapiens 61120 R-HSA-68917 https://reactome.org/PathwayBrowser/#/R-HSA-68917 Cdc45 associates with the pre-replicative complex at the origin TAS Homo sapiens 61120 R-HSA-68918 https://reactome.org/PathwayBrowser/#/R-HSA-68918 CDK and DDK associate with the Mcm10:pre-replicative complex TAS Homo sapiens 61120 R-HSA-68919 https://reactome.org/PathwayBrowser/#/R-HSA-68919 Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 TAS Homo sapiens 61120 R-HSA-68940 https://reactome.org/PathwayBrowser/#/R-HSA-68940 Cdt1 is displaced from the pre-replicative complex. TAS Homo sapiens 61120 R-HSA-68944 https://reactome.org/PathwayBrowser/#/R-HSA-68944 Orc1 is phosphorylated by cyclin A/CDK2 TAS Homo sapiens 61120 R-HSA-68950 https://reactome.org/PathwayBrowser/#/R-HSA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin TAS Homo sapiens 61120 R-HSA-68960 https://reactome.org/PathwayBrowser/#/R-HSA-68960 DNA polymerase epsilon binds at the origin TAS Homo sapiens 61120 R-HSA-69053 https://reactome.org/PathwayBrowser/#/R-HSA-69053 RFC binding displaces Pol Alpha TAS Homo sapiens 61120 R-HSA-69063 https://reactome.org/PathwayBrowser/#/R-HSA-69063 Loading of PCNA - Sliding Clamp Formation TAS Homo sapiens 61120 R-HSA-69068 https://reactome.org/PathwayBrowser/#/R-HSA-69068 RFC dissociates after sliding clamp formation TAS Homo sapiens 61120 R-HSA-69074 https://reactome.org/PathwayBrowser/#/R-HSA-69074 Formation of Processive Complex TAS Homo sapiens 61120 R-HSA-69116 https://reactome.org/PathwayBrowser/#/R-HSA-69116 Formation of Okazaki fragments TAS Homo sapiens 61120 R-HSA-69127 https://reactome.org/PathwayBrowser/#/R-HSA-69127 Formation of the Flap Intermediate TAS Homo sapiens 61120 R-HSA-69140 https://reactome.org/PathwayBrowser/#/R-HSA-69140 RPA binds to the Flap TAS Homo sapiens 61120 R-HSA-69142 https://reactome.org/PathwayBrowser/#/R-HSA-69142 Recruitment of Dna2 endonuclease TAS Homo sapiens 61120 R-HSA-69144 https://reactome.org/PathwayBrowser/#/R-HSA-69144 Removal of RNA primer and dissociation of RPA and Dna2 TAS Homo sapiens 61120 R-HSA-69152 https://reactome.org/PathwayBrowser/#/R-HSA-69152 Removal of remaining Flap TAS Homo sapiens 61120 R-HSA-69173 https://reactome.org/PathwayBrowser/#/R-HSA-69173 Joining of adjacent Okazaki fragments TAS Homo sapiens 61120 R-HSA-69891 https://reactome.org/PathwayBrowser/#/R-HSA-69891 Phosphorylation and activation of CHEK2 by ATM TAS Homo sapiens 61120 R-HSA-73718 https://reactome.org/PathwayBrowser/#/R-HSA-73718 UBF-1 Binds rDNA Promoter TAS Homo sapiens 61120 R-HSA-73722 https://reactome.org/PathwayBrowser/#/R-HSA-73722 Phosphorylation of UBF-1:rDNA Promoter TAS Homo sapiens 61120 R-HSA-73739 https://reactome.org/PathwayBrowser/#/R-HSA-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter TAS Homo sapiens 61120 R-HSA-73758 https://reactome.org/PathwayBrowser/#/R-HSA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter TAS Homo sapiens 61120 R-HSA-73769 https://reactome.org/PathwayBrowser/#/R-HSA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex TAS Homo sapiens 61120 R-HSA-73946 https://reactome.org/PathwayBrowser/#/R-HSA-73946 Abortive initiation after formation of the first phosphodiester bond TAS Homo sapiens 61120 R-HSA-75095 https://reactome.org/PathwayBrowser/#/R-HSA-75095 Binding of TFIIE to the growing preinitiation complex TAS Homo sapiens 61120 R-HSA-75850 https://reactome.org/PathwayBrowser/#/R-HSA-75850 Addition of the third nucleotide on the nascent transcript TAS Homo sapiens 61120 R-HSA-75856 https://reactome.org/PathwayBrowser/#/R-HSA-75856 Abortive Initiation Before Second Transition TAS Homo sapiens 61120 R-HSA-75861 https://reactome.org/PathwayBrowser/#/R-HSA-75861 NTP Binds Active Site of RNA Polymerase II TAS Homo sapiens 61120 R-HSA-75862 https://reactome.org/PathwayBrowser/#/R-HSA-75862 Fall Back to Closed Pre-initiation Complex TAS Homo sapiens 61120 R-HSA-75864 https://reactome.org/PathwayBrowser/#/R-HSA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released TAS Homo sapiens 61120 R-HSA-75866 https://reactome.org/PathwayBrowser/#/R-HSA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP TAS Homo sapiens 61120 R-HSA-75869 https://reactome.org/PathwayBrowser/#/R-HSA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition TAS Homo sapiens 61120 R-HSA-75873 https://reactome.org/PathwayBrowser/#/R-HSA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript TAS Homo sapiens 61120 R-HSA-75891 https://reactome.org/PathwayBrowser/#/R-HSA-75891 Abortive Initiation After Second Transition TAS Homo sapiens 61120 R-HSA-75949 https://reactome.org/PathwayBrowser/#/R-HSA-75949 RNA Polymerase II Promoter Opening: First Transition TAS Homo sapiens 61120 R-HSA-76052 https://reactome.org/PathwayBrowser/#/R-HSA-76052 Binding of TFIIIA To type 1 Promoter TAS Homo sapiens 61120 R-HSA-76054 https://reactome.org/PathwayBrowser/#/R-HSA-76054 Binding of TFIIIC to TFIIIA:Type I Promoter complex TAS Homo sapiens 61120 R-HSA-76056 https://reactome.org/PathwayBrowser/#/R-HSA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex TAS Homo sapiens 61120 R-HSA-76060 https://reactome.org/PathwayBrowser/#/R-HSA-76060 RNA Polymerase III Promoter Opening at Type 1 Promoters IEA Homo sapiens 61120 R-HSA-76576 https://reactome.org/PathwayBrowser/#/R-HSA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition TAS Homo sapiens 61120 R-HSA-77068 https://reactome.org/PathwayBrowser/#/R-HSA-77068 Activation of GT TAS Homo sapiens 61120 R-HSA-77069 https://reactome.org/PathwayBrowser/#/R-HSA-77069 RNA Polymerase II CTD (phosphorylated) binds to CE TAS Homo sapiens 61120 R-HSA-77071 https://reactome.org/PathwayBrowser/#/R-HSA-77071 Phosphorylation (Ser5) of RNA pol II CTD TAS Homo sapiens 61120 R-HSA-77073 https://reactome.org/PathwayBrowser/#/R-HSA-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) TAS Homo sapiens 61120 R-HSA-77077 https://reactome.org/PathwayBrowser/#/R-HSA-77077 Capping complex formation TAS Homo sapiens 61120 R-HSA-77078 https://reactome.org/PathwayBrowser/#/R-HSA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme TAS Homo sapiens 61120 R-HSA-77081 https://reactome.org/PathwayBrowser/#/R-HSA-77081 Formation of the CE:GMP intermediate complex TAS Homo sapiens 61120 R-HSA-77083 https://reactome.org/PathwayBrowser/#/R-HSA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA TAS Homo sapiens 61120 R-HSA-77085 https://reactome.org/PathwayBrowser/#/R-HSA-77085 Dissociation of transcript with 5'-GMP from GT TAS Homo sapiens 61120 R-HSA-77090 https://reactome.org/PathwayBrowser/#/R-HSA-77090 Methylation of GMP-cap by RNA Methyltransferase TAS Homo sapiens 61120 R-HSA-83723 https://reactome.org/PathwayBrowser/#/R-HSA-83723 Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex TAS Homo sapiens 61120 R-HSA-83788 https://reactome.org/PathwayBrowser/#/R-HSA-83788 Binding of TFIIIC to Type 2 promoter TAS Homo sapiens 61120 R-HSA-83790 https://reactome.org/PathwayBrowser/#/R-HSA-83790 Binding of TFIIIB to TFIIC: Type 2 Promoter Complex TAS Homo sapiens 61120 R-HSA-83791 https://reactome.org/PathwayBrowser/#/R-HSA-83791 Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter TAS Homo sapiens 61120 R-HSA-83793 https://reactome.org/PathwayBrowser/#/R-HSA-83793 Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex TAS Homo sapiens 61120 R-HSA-83803 https://reactome.org/PathwayBrowser/#/R-HSA-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex TAS Homo sapiens 61120 R-HSA-83805 https://reactome.org/PathwayBrowser/#/R-HSA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex TAS Homo sapiens 61120 R-HSA-879724 https://reactome.org/PathwayBrowser/#/R-HSA-879724 Expression of PPARA IEA Homo sapiens 61120 R-HSA-9023941 https://reactome.org/PathwayBrowser/#/R-HSA-9023941 MRN:CtIP endonucleolytically cleaves single-strand DNA 3' to SPO11 IEA Homo sapiens 61120 R-HSA-9023943 https://reactome.org/PathwayBrowser/#/R-HSA-9023943 MRN:CtIP exonucleolytically hydrolyzes DNA 3' to SPO11 and SPO11:double-strand break dissociates to SPO11:oligonucleotide and resected 5' end IEA Homo sapiens 61120 R-HSA-912368 https://reactome.org/PathwayBrowser/#/R-HSA-912368 SPO11 hydrolyzes DNA forming double-strand breaks IEA Homo sapiens 61120 R-HSA-912429 https://reactome.org/PathwayBrowser/#/R-HSA-912429 Resolution of meiotic holliday junction IEA Homo sapiens 61120 R-HSA-912458 https://reactome.org/PathwayBrowser/#/R-HSA-912458 Formation of meiotic heteroduplex IEA Homo sapiens 61120 R-HSA-912496 https://reactome.org/PathwayBrowser/#/R-HSA-912496 Formation of meiotic holliday junction IEA Homo sapiens 61120 R-HSA-912503 https://reactome.org/PathwayBrowser/#/R-HSA-912503 Formation of meiotic single-stranded DNA invasion complex IEA Homo sapiens 61120 R-HSA-9604480 https://reactome.org/PathwayBrowser/#/R-HSA-9604480 NFkB complex translocates from the cytosol to the nucleus TAS Homo sapiens 61120 R-HSA-9604487 https://reactome.org/PathwayBrowser/#/R-HSA-9604487 p-IRF7:p-IRF7 translocates to the nucleus TAS Homo sapiens 61120 R-HSA-9613494 https://reactome.org/PathwayBrowser/#/R-HSA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition TAS Homo sapiens 61120 R-HSA-9613497 https://reactome.org/PathwayBrowser/#/R-HSA-9613497 Unwinding DNA for the nascent transcript TAS Homo sapiens 61120 R-HSA-9670149 https://reactome.org/PathwayBrowser/#/R-HSA-9670149 TERRA transcription TAS Homo sapiens 61120 R-HSA-9684118 https://reactome.org/PathwayBrowser/#/R-HSA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER TAS Homo sapiens 61120 R-HSA-9701199 https://reactome.org/PathwayBrowser/#/R-HSA-9701199 Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of BRCA1 in PALB2 binding TAS Homo sapiens 61120 R-HSA-9704330 https://reactome.org/PathwayBrowser/#/R-HSA-9704330 Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in BRCA1 binding TAS Homo sapiens 61120 R-HSA-9704408 https://reactome.org/PathwayBrowser/#/R-HSA-9704408 Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in binding to BRCA2/RAD51/RAD51C TAS Homo sapiens 61120 R-HSA-9709571 https://reactome.org/PathwayBrowser/#/R-HSA-9709571 BRCA2 mutants with BRC defects or a defect in the C-terminal RAD51 binding site do not bind RAD51 TAS Homo sapiens 61120 R-HSA-9709601 https://reactome.org/PathwayBrowser/#/R-HSA-9709601 Defective recruitment of BRCA2 and RAD51 due to loss of BRCA2 function in PALB2 binding TAS Homo sapiens 61120 R-HSA-9710480 https://reactome.org/PathwayBrowser/#/R-HSA-9710480 Decitabine triphosphate incorporates into DNA TAS Homo sapiens 61120 R-HSA-9734475 https://reactome.org/PathwayBrowser/#/R-HSA-9734475 PPARA binds fibrates TAS Homo sapiens 61120 R-HSA-9749098 https://reactome.org/PathwayBrowser/#/R-HSA-9749098 ORC1 binds to DNA at origin of replication sites TAS Homo sapiens 61120 R-HSA-9749320 https://reactome.org/PathwayBrowser/#/R-HSA-9749320 CDT1-mediated loading of MCM2-7 to replication origins IEA Homo sapiens 61120 R-HSA-9749350 https://reactome.org/PathwayBrowser/#/R-HSA-9749350 ATP-dependent release of CDT1 from the OCCM complex IEA Homo sapiens 61120 R-HSA-9749351 https://reactome.org/PathwayBrowser/#/R-HSA-9749351 CDT1-mediated formation of MCM2-7 double hexamer at the replication origin IEA Homo sapiens 61120 R-HSA-975098 https://reactome.org/PathwayBrowser/#/R-HSA-975098 MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 TAS Homo sapiens 61120 R-HSA-975100 https://reactome.org/PathwayBrowser/#/R-HSA-975100 Dissociation of hp-IRAK1/or IRAK2:TRAF6-oligomer from the p-IRAK4 :oligo-Myd88:activated TLR7/8 or 9 complex TAS Homo sapiens 61120 R-HSA-975106 https://reactome.org/PathwayBrowser/#/R-HSA-975106 Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 61120 R-HSA-975111 https://reactome.org/PathwayBrowser/#/R-HSA-975111 TRAF6 binds to hp- IRAK1/or p-IRAK2:p-IRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 61120 R-HSA-975115 https://reactome.org/PathwayBrowser/#/R-HSA-975115 IRAK1/or IRAK2 binds to the activated IRAK4 :MyD88:activated TLR 7/8 or 9. TAS Homo sapiens 61120 R-HSA-975118 https://reactome.org/PathwayBrowser/#/R-HSA-975118 TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex TAS Homo sapiens 61120 R-HSA-975125 https://reactome.org/PathwayBrowser/#/R-HSA-975125 Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 61120 R-HSA-975134 https://reactome.org/PathwayBrowser/#/R-HSA-975134 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 TAS Homo sapiens 61120 R-HSA-975156 https://reactome.org/PathwayBrowser/#/R-HSA-975156 IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex TAS Homo sapiens 61120 R-HSA-975160 https://reactome.org/PathwayBrowser/#/R-HSA-975160 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 TAS Homo sapiens 61120 R-HSA-975170 https://reactome.org/PathwayBrowser/#/R-HSA-975170 IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 61120 R-HSA-975175 https://reactome.org/PathwayBrowser/#/R-HSA-975175 MyD88 interacts with the activated TLR receptor 7, 8 or 9 TAS Homo sapiens 61120 R-HSA-975180 https://reactome.org/PathwayBrowser/#/R-HSA-975180 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 61120 R-HSA-975188 https://reactome.org/PathwayBrowser/#/R-HSA-975188 TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 61120 R-HSA-996727 https://reactome.org/PathwayBrowser/#/R-HSA-996727 REST recruits the BHC complex TAS Homo sapiens 61120 R-MMU-1008200 https://reactome.org/PathwayBrowser/#/R-MMU-1008200 NFE2 binds the beta globin locus control region IEA Mus musculus 61120 R-MMU-109636 https://reactome.org/PathwayBrowser/#/R-MMU-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Mus musculus 61120 R-MMU-109637 https://reactome.org/PathwayBrowser/#/R-MMU-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Mus musculus 61120 R-MMU-109638 https://reactome.org/PathwayBrowser/#/R-MMU-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Mus musculus 61120 R-MMU-109639 https://reactome.org/PathwayBrowser/#/R-MMU-109639 Formation of the closed pre-initiation complex IEA Mus musculus 61120 R-MMU-109699 https://reactome.org/PathwayBrowser/#/R-MMU-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Mus musculus 61120 R-MMU-111264 https://reactome.org/PathwayBrowser/#/R-MMU-111264 Addition of nucleotides between position +11 and +30 IEA Mus musculus 61120 R-MMU-112379 https://reactome.org/PathwayBrowser/#/R-MMU-112379 Recruitment of elongation factors to form elongation complex IEA Mus musculus 61120 R-MMU-112381 https://reactome.org/PathwayBrowser/#/R-MMU-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Mus musculus 61120 R-MMU-112385 https://reactome.org/PathwayBrowser/#/R-MMU-112385 Addition of nucleotides leads to transcript elongation IEA Mus musculus 61120 R-MMU-113429 https://reactome.org/PathwayBrowser/#/R-MMU-113429 Elongating transcript encounters a lesion in the template IEA Mus musculus 61120 R-MMU-113430 https://reactome.org/PathwayBrowser/#/R-MMU-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Mus musculus 61120 R-MMU-113503 https://reactome.org/PathwayBrowser/#/R-MMU-113503 PP2A mediated localization of RB1 protein in chromatin IEA Mus musculus 61120 R-MMU-113504 https://reactome.org/PathwayBrowser/#/R-MMU-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Mus musculus 61120 R-MMU-1535903 https://reactome.org/PathwayBrowser/#/R-MMU-1535903 Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements IEA Mus musculus 61120 R-MMU-163296 https://reactome.org/PathwayBrowser/#/R-MMU-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Mus musculus 61120 R-MMU-163310 https://reactome.org/PathwayBrowser/#/R-MMU-163310 TFAM binds to mitochondrial promoters IEA Mus musculus 61120 R-MMU-163320 https://reactome.org/PathwayBrowser/#/R-MMU-163320 Association of mTERF with the termination sequence IEA Mus musculus 61120 R-MMU-1679098 https://reactome.org/PathwayBrowser/#/R-MMU-1679098 Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer IEA Mus musculus 61120 R-MMU-1679589 https://reactome.org/PathwayBrowser/#/R-MMU-1679589 Engulfed CpG DNA binds to endosomal full-length TLR9 IEA Mus musculus 61120 R-MMU-174427 https://reactome.org/PathwayBrowser/#/R-MMU-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Mus musculus 61120 R-MMU-174438 https://reactome.org/PathwayBrowser/#/R-MMU-174438 Formation of the Flap Intermediate on the C-strand IEA Mus musculus 61120 R-MMU-174439 https://reactome.org/PathwayBrowser/#/R-MMU-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Mus musculus 61120 R-MMU-174441 https://reactome.org/PathwayBrowser/#/R-MMU-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Mus musculus 61120 R-MMU-174444 https://reactome.org/PathwayBrowser/#/R-MMU-174444 Formation of C-strand Okazaki fragments IEA Mus musculus 61120 R-MMU-174445 https://reactome.org/PathwayBrowser/#/R-MMU-174445 RPA binds to the Flap on the C-strand IEA Mus musculus 61120 R-MMU-174446 https://reactome.org/PathwayBrowser/#/R-MMU-174446 Removal of remaining Flap from the C-strand IEA Mus musculus 61120 R-MMU-174447 https://reactome.org/PathwayBrowser/#/R-MMU-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Mus musculus 61120 R-MMU-174448 https://reactome.org/PathwayBrowser/#/R-MMU-174448 Formation of Processive Complex on the C-strand of the telomere IEA Mus musculus 61120 R-MMU-174451 https://reactome.org/PathwayBrowser/#/R-MMU-174451 Recruitment of DNA2 endonuclease to the C strand IEA Mus musculus 61120 R-MMU-174452 https://reactome.org/PathwayBrowser/#/R-MMU-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Mus musculus 61120 R-MMU-174456 https://reactome.org/PathwayBrowser/#/R-MMU-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Mus musculus 61120 R-MMU-176101 https://reactome.org/PathwayBrowser/#/R-MMU-176101 Recruitment of Rad17-RFC complex to DNA IEA Mus musculus 61120 R-MMU-176175 https://reactome.org/PathwayBrowser/#/R-MMU-176175 Stalling of DNA replication fork and RPA binding IEA Mus musculus 61120 R-MMU-176250 https://reactome.org/PathwayBrowser/#/R-MMU-176250 Binding of ATR-ATRIP to the RPA-ssDNA complex IEA Mus musculus 61120 R-MMU-176264 https://reactome.org/PathwayBrowser/#/R-MMU-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Mus musculus 61120 R-MMU-187895 https://reactome.org/PathwayBrowser/#/R-MMU-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 IEA Mus musculus 61120 R-MMU-188002 https://reactome.org/PathwayBrowser/#/R-MMU-188002 Rab5-mediated recruitment of class III PI3K to TLR9 IEA Mus musculus 61120 R-MMU-211247 https://reactome.org/PathwayBrowser/#/R-MMU-211247 Cleavage of DNA by DFF40 IEA Mus musculus 61120 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 61120 R-MMU-2247510 https://reactome.org/PathwayBrowser/#/R-MMU-2247510 MARCO:ligand is endocytosed IEA Mus musculus 61120 R-MMU-3134883 https://reactome.org/PathwayBrowser/#/R-MMU-3134883 Beta-catenin enhances association of IRF3 with CBP/p300 IEA Mus musculus 61120 R-MMU-3134953 https://reactome.org/PathwayBrowser/#/R-MMU-3134953 DHX36 or DHX9 binds MyD88 IEA Mus musculus 61120 R-MMU-3134954 https://reactome.org/PathwayBrowser/#/R-MMU-3134954 DHX9 binds DNA IEA Mus musculus 61120 R-MMU-3134962 https://reactome.org/PathwayBrowser/#/R-MMU-3134962 DHX36 binds DNA IEA Mus musculus 61120 R-MMU-3785711 https://reactome.org/PathwayBrowser/#/R-MMU-3785711 Telomere shortening during replicative exhaustion IEA Mus musculus 61120 R-MMU-3785768 https://reactome.org/PathwayBrowser/#/R-MMU-3785768 MRN complex binds DNA double strand breaks IEA Mus musculus 61120 R-MMU-400143 https://reactome.org/PathwayBrowser/#/R-MMU-400143 Fatty acid ligands activate PPARA IEA Mus musculus 61120 R-MMU-400183 https://reactome.org/PathwayBrowser/#/R-MMU-400183 PPARA:RXRA binds Corepressors of PPARA IEA Mus musculus 61120 R-MMU-400204 https://reactome.org/PathwayBrowser/#/R-MMU-400204 PPARA binds RXRA IEA Mus musculus 61120 R-MMU-5250930 https://reactome.org/PathwayBrowser/#/R-MMU-5250930 B-WICH recruits histone acetyltransferases IEA Mus musculus 61120 R-MMU-5250947 https://reactome.org/PathwayBrowser/#/R-MMU-5250947 B-WICH complex binds rDNA promoter IEA Mus musculus 61120 R-MMU-5682018 https://reactome.org/PathwayBrowser/#/R-MMU-5682018 MRN complex bound to shortened telomeres recruits ATM IEA Mus musculus 61120 R-MMU-5682020 https://reactome.org/PathwayBrowser/#/R-MMU-5682020 MRN complex binds shortened telomeres IEA Mus musculus 61120 R-MMU-5682026 https://reactome.org/PathwayBrowser/#/R-MMU-5682026 MRN bound to shortened telomeres activates ATM IEA Mus musculus 61120 R-MMU-5682044 https://reactome.org/PathwayBrowser/#/R-MMU-5682044 KAT5 acetylates ATM at DNA DSBs IEA Mus musculus 61120 R-MMU-5682586 https://reactome.org/PathwayBrowser/#/R-MMU-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Mus musculus 61120 R-MMU-5682588 https://reactome.org/PathwayBrowser/#/R-MMU-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Mus musculus 61120 R-MMU-5682598 https://reactome.org/PathwayBrowser/#/R-MMU-5682598 ATM phosphorylates HERC2 IEA Mus musculus 61120 R-MMU-5682607 https://reactome.org/PathwayBrowser/#/R-MMU-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Mus musculus 61120 R-MMU-5682629 https://reactome.org/PathwayBrowser/#/R-MMU-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Mus musculus 61120 R-MMU-5682858 https://reactome.org/PathwayBrowser/#/R-MMU-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Mus musculus 61120 R-MMU-5682863 https://reactome.org/PathwayBrowser/#/R-MMU-5682863 RNF168 binds DNA DSBs IEA Mus musculus 61120 R-MMU-5682965 https://reactome.org/PathwayBrowser/#/R-MMU-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Mus musculus 61120 R-MMU-5682967 https://reactome.org/PathwayBrowser/#/R-MMU-5682967 WHSC1 binds DNA DSBs IEA Mus musculus 61120 R-MMU-5682983 https://reactome.org/PathwayBrowser/#/R-MMU-5682983 ATM phosphorylates WHSC1 IEA Mus musculus 61120 R-MMU-5682992 https://reactome.org/PathwayBrowser/#/R-MMU-5682992 KDM4A,B bind H4K20Me2 IEA Mus musculus 61120 R-MMU-5683077 https://reactome.org/PathwayBrowser/#/R-MMU-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Mus musculus 61120 R-MMU-5683384 https://reactome.org/PathwayBrowser/#/R-MMU-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Mus musculus 61120 R-MMU-5683385 https://reactome.org/PathwayBrowser/#/R-MMU-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Mus musculus 61120 R-MMU-5683405 https://reactome.org/PathwayBrowser/#/R-MMU-5683405 PPP5C dephosphorylates TP53BP1 IEA Mus musculus 61120 R-MMU-5683425 https://reactome.org/PathwayBrowser/#/R-MMU-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Mus musculus 61120 R-MMU-5683735 https://reactome.org/PathwayBrowser/#/R-MMU-5683735 CHEK2 is recruited to DNA DSBs IEA Mus musculus 61120 R-MMU-5683801 https://reactome.org/PathwayBrowser/#/R-MMU-5683801 CHEK2 phosphorylates BRCA1 IEA Mus musculus 61120 R-MMU-5683964 https://reactome.org/PathwayBrowser/#/R-MMU-5683964 ATM phosphorylates EYA1-4 IEA Mus musculus 61120 R-MMU-5683967 https://reactome.org/PathwayBrowser/#/R-MMU-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Mus musculus 61120 R-MMU-5683986 https://reactome.org/PathwayBrowser/#/R-MMU-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA Mus musculus 61120 R-MMU-5684052 https://reactome.org/PathwayBrowser/#/R-MMU-5684052 PIAS4 SUMOylates MDC1 IEA Mus musculus 61120 R-MMU-5684071 https://reactome.org/PathwayBrowser/#/R-MMU-5684071 RNF4 ubiquitinates MDC1 IEA Mus musculus 61120 R-MMU-5684081 https://reactome.org/PathwayBrowser/#/R-MMU-5684081 MRN complex binds CDK2 and RBBP8 IEA Mus musculus 61120 R-MMU-5684096 https://reactome.org/PathwayBrowser/#/R-MMU-5684096 CDK2 phosphorylates RBBP8 IEA Mus musculus 61120 R-MMU-5684108 https://reactome.org/PathwayBrowser/#/R-MMU-5684108 BRCA1 binds phosphorylated RBBP8 IEA Mus musculus 61120 R-MMU-5684140 https://reactome.org/PathwayBrowser/#/R-MMU-5684140 ATM phosphorylates RBBP8 IEA Mus musculus 61120 R-MMU-5684875 https://reactome.org/PathwayBrowser/#/R-MMU-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Mus musculus 61120 R-MMU-5684882 https://reactome.org/PathwayBrowser/#/R-MMU-5684882 CHEK1 is recruited to resected DNA DSBs IEA Mus musculus 61120 R-MMU-5684887 https://reactome.org/PathwayBrowser/#/R-MMU-5684887 Activation of CHEK1 at resected DNA DSBs IEA Mus musculus 61120 R-MMU-5685011 https://reactome.org/PathwayBrowser/#/R-MMU-5685011 ATR activation at DNA DSBs IEA Mus musculus 61120 R-MMU-5685156 https://reactome.org/PathwayBrowser/#/R-MMU-5685156 ATR phosphorylates RPA2 IEA Mus musculus 61120 R-MMU-5685341 https://reactome.org/PathwayBrowser/#/R-MMU-5685341 BCDX2 complex stabilizes RAD51 filament IEA Mus musculus 61120 R-MMU-5685838 https://reactome.org/PathwayBrowser/#/R-MMU-5685838 CX3 complex binds D-loop structures IEA Mus musculus 61120 R-MMU-5685985 https://reactome.org/PathwayBrowser/#/R-MMU-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Mus musculus 61120 R-MMU-5685994 https://reactome.org/PathwayBrowser/#/R-MMU-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Mus musculus 61120 R-MMU-5686440 https://reactome.org/PathwayBrowser/#/R-MMU-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Mus musculus 61120 R-MMU-5686642 https://reactome.org/PathwayBrowser/#/R-MMU-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Mus musculus 61120 R-MMU-5686657 https://reactome.org/PathwayBrowser/#/R-MMU-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Mus musculus 61120 R-MMU-5686685 https://reactome.org/PathwayBrowser/#/R-MMU-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Mus musculus 61120 R-MMU-5686704 https://reactome.org/PathwayBrowser/#/R-MMU-5686704 Activated ATM phosphorylates DCLRE1C IEA Mus musculus 61120 R-MMU-5686900 https://reactome.org/PathwayBrowser/#/R-MMU-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Mus musculus 61120 R-MMU-5686924 https://reactome.org/PathwayBrowser/#/R-MMU-5686924 DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs IEA Mus musculus 61120 R-MMU-5687183 https://reactome.org/PathwayBrowser/#/R-MMU-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Mus musculus 61120 R-MMU-5687360 https://reactome.org/PathwayBrowser/#/R-MMU-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Mus musculus 61120 R-MMU-5687464 https://reactome.org/PathwayBrowser/#/R-MMU-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Mus musculus 61120 R-MMU-5687465 https://reactome.org/PathwayBrowser/#/R-MMU-5687465 MRN complex binds RBBP8 IEA Mus musculus 61120 R-MMU-5687484 https://reactome.org/PathwayBrowser/#/R-MMU-5687484 PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site IEA Mus musculus 61120 R-MMU-5687640 https://reactome.org/PathwayBrowser/#/R-MMU-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Mus musculus 61120 R-MMU-5687653 https://reactome.org/PathwayBrowser/#/R-MMU-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Mus musculus 61120 R-MMU-5687664 https://reactome.org/PathwayBrowser/#/R-MMU-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Mus musculus 61120 R-MMU-5687673 https://reactome.org/PathwayBrowser/#/R-MMU-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites IEA Mus musculus 61120 R-MMU-5687675 https://reactome.org/PathwayBrowser/#/R-MMU-5687675 LIG3 ligates remaining SSBs in MMEJ IEA Mus musculus 61120 R-MMU-5689317 https://reactome.org/PathwayBrowser/#/R-MMU-5689317 Formation of the pre-incision complex in GG-NER IEA Mus musculus 61120 R-MMU-5689861 https://reactome.org/PathwayBrowser/#/R-MMU-5689861 Recruitment of XPA and release of CAK IEA Mus musculus 61120 R-MMU-5690213 https://reactome.org/PathwayBrowser/#/R-MMU-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Mus musculus 61120 R-MMU-5690988 https://reactome.org/PathwayBrowser/#/R-MMU-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Mus musculus 61120 R-MMU-5690990 https://reactome.org/PathwayBrowser/#/R-MMU-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Mus musculus 61120 R-MMU-5690991 https://reactome.org/PathwayBrowser/#/R-MMU-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Mus musculus 61120 R-MMU-5690996 https://reactome.org/PathwayBrowser/#/R-MMU-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Mus musculus 61120 R-MMU-5691000 https://reactome.org/PathwayBrowser/#/R-MMU-5691000 TFIIH binds GG-NER site to form a verification complex IEA Mus musculus 61120 R-MMU-5691001 https://reactome.org/PathwayBrowser/#/R-MMU-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Mus musculus 61120 R-MMU-5691006 https://reactome.org/PathwayBrowser/#/R-MMU-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Mus musculus 61120 R-MMU-5693533 https://reactome.org/PathwayBrowser/#/R-MMU-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends IEA Mus musculus 61120 R-MMU-5693536 https://reactome.org/PathwayBrowser/#/R-MMU-5693536 ATM phosphorylates MDC1 IEA Mus musculus 61120 R-MMU-5693539 https://reactome.org/PathwayBrowser/#/R-MMU-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Mus musculus 61120 R-MMU-5693540 https://reactome.org/PathwayBrowser/#/R-MMU-5693540 MRN activates ATM IEA Mus musculus 61120 R-MMU-5693542 https://reactome.org/PathwayBrowser/#/R-MMU-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Mus musculus 61120 R-MMU-5693549 https://reactome.org/PathwayBrowser/#/R-MMU-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Mus musculus 61120 R-MMU-5693551 https://reactome.org/PathwayBrowser/#/R-MMU-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Mus musculus 61120 R-MMU-5693564 https://reactome.org/PathwayBrowser/#/R-MMU-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Mus musculus 61120 R-MMU-5693566 https://reactome.org/PathwayBrowser/#/R-MMU-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Mus musculus 61120 R-MMU-5693574 https://reactome.org/PathwayBrowser/#/R-MMU-5693574 XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ IEA Mus musculus 61120 R-MMU-5693575 https://reactome.org/PathwayBrowser/#/R-MMU-5693575 DNA-PKcs autophosphorylates IEA Mus musculus 61120 R-MMU-5693578 https://reactome.org/PathwayBrowser/#/R-MMU-5693578 TDP1 and TDP2 process unligatable DSB ends IEA Mus musculus 61120 R-MMU-5693580 https://reactome.org/PathwayBrowser/#/R-MMU-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Mus musculus 61120 R-MMU-5693583 https://reactome.org/PathwayBrowser/#/R-MMU-5693583 MDC1 associates with gamma-H2AFX at nuclear foci IEA Mus musculus 61120 R-MMU-5693584 https://reactome.org/PathwayBrowser/#/R-MMU-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Mus musculus 61120 R-MMU-5693593 https://reactome.org/PathwayBrowser/#/R-MMU-5693593 D-loop extension by DNA polymerases IEA Mus musculus 61120 R-MMU-5693598 https://reactome.org/PathwayBrowser/#/R-MMU-5693598 ATM phosphorylates NBN IEA Mus musculus 61120 R-MMU-5693599 https://reactome.org/PathwayBrowser/#/R-MMU-5693599 Association of Ku heterodimer with ends of DNA double-strand break IEA Mus musculus 61120 R-MMU-5693602 https://reactome.org/PathwayBrowser/#/R-MMU-5693602 ATM recognizes H2AFX-Nucleosomes IEA Mus musculus 61120 R-MMU-5693608 https://reactome.org/PathwayBrowser/#/R-MMU-5693608 Initial resection of double-strand break ends IEA Mus musculus 61120 R-MMU-5693612 https://reactome.org/PathwayBrowser/#/R-MMU-5693612 MRN complex bound to DNA ends recruits ATM IEA Mus musculus 61120 R-MMU-5693615 https://reactome.org/PathwayBrowser/#/R-MMU-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis IEA Mus musculus 61120 R-MMU-5693620 https://reactome.org/PathwayBrowser/#/R-MMU-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Mus musculus 61120 R-MMU-5696655 https://reactome.org/PathwayBrowser/#/R-MMU-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Mus musculus 61120 R-MMU-5696664 https://reactome.org/PathwayBrowser/#/R-MMU-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Mus musculus 61120 R-MMU-5696670 https://reactome.org/PathwayBrowser/#/R-MMU-5696670 CHD1L is recruited to GG-NER site IEA Mus musculus 61120 R-MMU-6781818 https://reactome.org/PathwayBrowser/#/R-MMU-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Mus musculus 61120 R-MMU-6781824 https://reactome.org/PathwayBrowser/#/R-MMU-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Mus musculus 61120 R-MMU-6781833 https://reactome.org/PathwayBrowser/#/R-MMU-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Mus musculus 61120 R-MMU-6781840 https://reactome.org/PathwayBrowser/#/R-MMU-6781840 ERCC6 binds stalled RNA Pol II IEA Mus musculus 61120 R-MMU-6781867 https://reactome.org/PathwayBrowser/#/R-MMU-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Mus musculus 61120 R-MMU-6782004 https://reactome.org/PathwayBrowser/#/R-MMU-6782004 Assembly of the pre-incision complex in TC-NER IEA Mus musculus 61120 R-MMU-6782069 https://reactome.org/PathwayBrowser/#/R-MMU-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Mus musculus 61120 R-MMU-6782131 https://reactome.org/PathwayBrowser/#/R-MMU-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Mus musculus 61120 R-MMU-6782138 https://reactome.org/PathwayBrowser/#/R-MMU-6782138 ERCC5 and RPA bind TC-NER site IEA Mus musculus 61120 R-MMU-6782141 https://reactome.org/PathwayBrowser/#/R-MMU-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Mus musculus 61120 R-MMU-6782204 https://reactome.org/PathwayBrowser/#/R-MMU-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Mus musculus 61120 R-MMU-6782208 https://reactome.org/PathwayBrowser/#/R-MMU-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Mus musculus 61120 R-MMU-6782211 https://reactome.org/PathwayBrowser/#/R-MMU-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Mus musculus 61120 R-MMU-6782224 https://reactome.org/PathwayBrowser/#/R-MMU-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Mus musculus 61120 R-MMU-6782227 https://reactome.org/PathwayBrowser/#/R-MMU-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Mus musculus 61120 R-MMU-6782943 https://reactome.org/PathwayBrowser/#/R-MMU-6782943 UV-DDB ubiquitinates XPC IEA Mus musculus 61120 R-MMU-6786166 https://reactome.org/PathwayBrowser/#/R-MMU-6786166 Translesion synthesis across unhooked ICL by POLN IEA Mus musculus 61120 R-MMU-6790454 https://reactome.org/PathwayBrowser/#/R-MMU-6790454 SUMOylation of XPC IEA Mus musculus 61120 R-MMU-6790487 https://reactome.org/PathwayBrowser/#/R-MMU-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Mus musculus 61120 R-MMU-6792712 https://reactome.org/PathwayBrowser/#/R-MMU-6792712 KAT5 acetylates ATM at shortened telomeres IEA Mus musculus 61120 R-MMU-6799332 https://reactome.org/PathwayBrowser/#/R-MMU-6799332 ATR phosphorylates TP53 IEA Mus musculus 61120 R-MMU-68913 https://reactome.org/PathwayBrowser/#/R-MMU-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Mus musculus 61120 R-MMU-68914 https://reactome.org/PathwayBrowser/#/R-MMU-68914 DNA polymerase alpha:primase binds at the origin IEA Mus musculus 61120 R-MMU-68944 https://reactome.org/PathwayBrowser/#/R-MMU-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Mus musculus 61120 R-MMU-68950 https://reactome.org/PathwayBrowser/#/R-MMU-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Mus musculus 61120 R-MMU-68960 https://reactome.org/PathwayBrowser/#/R-MMU-68960 DNA polymerase epsilon binds at the origin IEA Mus musculus 61120 R-MMU-69053 https://reactome.org/PathwayBrowser/#/R-MMU-69053 RFC binding displaces Pol Alpha IEA Mus musculus 61120 R-MMU-69063 https://reactome.org/PathwayBrowser/#/R-MMU-69063 Loading of PCNA - Sliding Clamp Formation IEA Mus musculus 61120 R-MMU-69068 https://reactome.org/PathwayBrowser/#/R-MMU-69068 RFC dissociates after sliding clamp formation IEA Mus musculus 61120 R-MMU-69074 https://reactome.org/PathwayBrowser/#/R-MMU-69074 Formation of Processive Complex IEA Mus musculus 61120 R-MMU-69116 https://reactome.org/PathwayBrowser/#/R-MMU-69116 Formation of Okazaki fragments IEA Mus musculus 61120 R-MMU-69127 https://reactome.org/PathwayBrowser/#/R-MMU-69127 Formation of the Flap Intermediate IEA Mus musculus 61120 R-MMU-69140 https://reactome.org/PathwayBrowser/#/R-MMU-69140 RPA binds to the Flap IEA Mus musculus 61120 R-MMU-69142 https://reactome.org/PathwayBrowser/#/R-MMU-69142 Recruitment of Dna2 endonuclease IEA Mus musculus 61120 R-MMU-69144 https://reactome.org/PathwayBrowser/#/R-MMU-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Mus musculus 61120 R-MMU-69152 https://reactome.org/PathwayBrowser/#/R-MMU-69152 Removal of remaining Flap IEA Mus musculus 61120 R-MMU-69173 https://reactome.org/PathwayBrowser/#/R-MMU-69173 Joining of adjacent Okazaki fragments IEA Mus musculus 61120 R-MMU-69891 https://reactome.org/PathwayBrowser/#/R-MMU-69891 Phosphorylation and activation of CHEK2 by ATM IEA Mus musculus 61120 R-MMU-73718 https://reactome.org/PathwayBrowser/#/R-MMU-73718 UBF-1 Binds rDNA Promoter IEA Mus musculus 61120 R-MMU-73722 https://reactome.org/PathwayBrowser/#/R-MMU-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Mus musculus 61120 R-MMU-73739 https://reactome.org/PathwayBrowser/#/R-MMU-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Mus musculus 61120 R-MMU-73758 https://reactome.org/PathwayBrowser/#/R-MMU-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Mus musculus 61120 R-MMU-73769 https://reactome.org/PathwayBrowser/#/R-MMU-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Mus musculus 61120 R-MMU-73946 https://reactome.org/PathwayBrowser/#/R-MMU-73946 Abortive initiation after formation of the first phosphodiester bond IEA Mus musculus 61120 R-MMU-75095 https://reactome.org/PathwayBrowser/#/R-MMU-75095 Binding of TFIIE to the growing preinitiation complex IEA Mus musculus 61120 R-MMU-75850 https://reactome.org/PathwayBrowser/#/R-MMU-75850 Addition of the third nucleotide on the nascent transcript IEA Mus musculus 61120 R-MMU-75856 https://reactome.org/PathwayBrowser/#/R-MMU-75856 Abortive Initiation Before Second Transition IEA Mus musculus 61120 R-MMU-75861 https://reactome.org/PathwayBrowser/#/R-MMU-75861 NTP Binds Active Site of RNA Polymerase II IEA Mus musculus 61120 R-MMU-75862 https://reactome.org/PathwayBrowser/#/R-MMU-75862 Fall Back to Closed Pre-initiation Complex IEA Mus musculus 61120 R-MMU-75864 https://reactome.org/PathwayBrowser/#/R-MMU-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Mus musculus 61120 R-MMU-75866 https://reactome.org/PathwayBrowser/#/R-MMU-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Mus musculus 61120 R-MMU-75869 https://reactome.org/PathwayBrowser/#/R-MMU-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Mus musculus 61120 R-MMU-75873 https://reactome.org/PathwayBrowser/#/R-MMU-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Mus musculus 61120 R-MMU-75891 https://reactome.org/PathwayBrowser/#/R-MMU-75891 Abortive Initiation After Second Transition IEA Mus musculus 61120 R-MMU-75949 https://reactome.org/PathwayBrowser/#/R-MMU-75949 RNA Polymerase II Promoter Opening: First Transition IEA Mus musculus 61120 R-MMU-76052 https://reactome.org/PathwayBrowser/#/R-MMU-76052 Binding of TFIIIA To type 1 Promoter IEA Mus musculus 61120 R-MMU-76054 https://reactome.org/PathwayBrowser/#/R-MMU-76054 Binding of TFIIIC to TFIIIA:Type I Promoter complex IEA Mus musculus 61120 R-MMU-76056 https://reactome.org/PathwayBrowser/#/R-MMU-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Mus musculus 61120 R-MMU-76576 https://reactome.org/PathwayBrowser/#/R-MMU-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Mus musculus 61120 R-MMU-77068 https://reactome.org/PathwayBrowser/#/R-MMU-77068 Activation of GT IEA Mus musculus 61120 R-MMU-77069 https://reactome.org/PathwayBrowser/#/R-MMU-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Mus musculus 61120 R-MMU-77071 https://reactome.org/PathwayBrowser/#/R-MMU-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Mus musculus 61120 R-MMU-77073 https://reactome.org/PathwayBrowser/#/R-MMU-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Mus musculus 61120 R-MMU-77077 https://reactome.org/PathwayBrowser/#/R-MMU-77077 Capping complex formation IEA Mus musculus 61120 R-MMU-77078 https://reactome.org/PathwayBrowser/#/R-MMU-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Mus musculus 61120 R-MMU-77081 https://reactome.org/PathwayBrowser/#/R-MMU-77081 Formation of the CE:GMP intermediate complex IEA Mus musculus 61120 R-MMU-77083 https://reactome.org/PathwayBrowser/#/R-MMU-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Mus musculus 61120 R-MMU-77085 https://reactome.org/PathwayBrowser/#/R-MMU-77085 Dissociation of transcript with 5'-GMP from GT IEA Mus musculus 61120 R-MMU-77090 https://reactome.org/PathwayBrowser/#/R-MMU-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Mus musculus 61120 R-MMU-83723 https://reactome.org/PathwayBrowser/#/R-MMU-83723 Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex IEA Mus musculus 61120 R-MMU-83788 https://reactome.org/PathwayBrowser/#/R-MMU-83788 Binding of TFIIIC to Type 2 promoter IEA Mus musculus 61120 R-MMU-83790 https://reactome.org/PathwayBrowser/#/R-MMU-83790 Binding of TFIIIB to TFIIC: Type 2 Promoter Complex IEA Mus musculus 61120 R-MMU-83793 https://reactome.org/PathwayBrowser/#/R-MMU-83793 Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex IEA Mus musculus 61120 R-MMU-83803 https://reactome.org/PathwayBrowser/#/R-MMU-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Mus musculus 61120 R-MMU-83805 https://reactome.org/PathwayBrowser/#/R-MMU-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Mus musculus 61120 R-MMU-912344 https://reactome.org/PathwayBrowser/#/R-MMU-912344 Formation of Double-strand Break in DNA by Spo11 TAS Mus musculus 61120 R-MMU-912357 https://reactome.org/PathwayBrowser/#/R-MMU-912357 Removal of Spo11 and Resection of 5' Ends of DNA TAS Mus musculus 61120 R-MMU-912421 https://reactome.org/PathwayBrowser/#/R-MMU-912421 Formation of Meiotic Single-stranded Invasion Complex TAS Mus musculus 61120 R-MMU-912431 https://reactome.org/PathwayBrowser/#/R-MMU-912431 Formation of Meiotic Heteroduplex TAS Mus musculus 61120 R-MMU-912462 https://reactome.org/PathwayBrowser/#/R-MMU-912462 Formation of Meiotic Holliday Junction TAS Mus musculus 61120 R-MMU-912487 https://reactome.org/PathwayBrowser/#/R-MMU-912487 Resolution of Meiotic Holliday Junction TAS Mus musculus 61120 R-MMU-9604480 https://reactome.org/PathwayBrowser/#/R-MMU-9604480 NFkB complex translocates from the cytosol to the nucleus IEA Mus musculus 61120 R-MMU-9604487 https://reactome.org/PathwayBrowser/#/R-MMU-9604487 p-IRF7:p-IRF7 translocates to the nucleus IEA Mus musculus 61120 R-MMU-9613494 https://reactome.org/PathwayBrowser/#/R-MMU-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Mus musculus 61120 R-MMU-9613497 https://reactome.org/PathwayBrowser/#/R-MMU-9613497 Unwinding DNA for the nascent transcript IEA Mus musculus 61120 R-MMU-9629360 https://reactome.org/PathwayBrowser/#/R-MMU-9629360 Neil3 recognizes and binds to thymine glycol in telomeric DNA TAS Mus musculus 61120 R-MMU-9629363 https://reactome.org/PathwayBrowser/#/R-MMU-9629363 Neil3 recognizes and binds to thymine glycol TAS Mus musculus 61120 R-MMU-9629370 https://reactome.org/PathwayBrowser/#/R-MMU-9629370 Neil3 recognizes and binds to spiroiminodihydantoin in telomeric DNA TAS Mus musculus 61120 R-MMU-9629485 https://reactome.org/PathwayBrowser/#/R-MMU-9629485 Neil3 cleaves spirominodihydantoin from telomeric DNA oligomer TAS Mus musculus 61120 R-MMU-9629509 https://reactome.org/PathwayBrowser/#/R-MMU-9629509 Neil3 cleaves thymine glycol TAS Mus musculus 61120 R-MMU-9629510 https://reactome.org/PathwayBrowser/#/R-MMU-9629510 Neil3 cleaves thymine glycol from telomeric DNA oligomer TAS Mus musculus 61120 R-MMU-9684118 https://reactome.org/PathwayBrowser/#/R-MMU-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Mus musculus 61120 R-MMU-9717136 https://reactome.org/PathwayBrowser/#/R-MMU-9717136 p-Smad2,3:Smad4:Foxh1 binds Activin Response Element TAS Mus musculus 61120 R-MMU-9734475 https://reactome.org/PathwayBrowser/#/R-MMU-9734475 PPARA binds fibrates IEA Mus musculus 61120 R-MMU-9749883 https://reactome.org/PathwayBrowser/#/R-MMU-9749883 Temozolomide produces DNA damage in the form of O6-methylguanine in mouse dsDNA TAS Mus musculus 61120 R-MMU-9750097 https://reactome.org/PathwayBrowser/#/R-MMU-9750097 ThioTEPA produces interstrand crosslinks in mouse DNA TAS Mus musculus 61120 R-MMU-9750281 https://reactome.org/PathwayBrowser/#/R-MMU-9750281 Uramustine produces interstrand crosslinks in mouse DNA TAS Mus musculus 61120 R-MMU-9817522 https://reactome.org/PathwayBrowser/#/R-MMU-9817522 Ung (Ung2) and base excision repair remove uridine and 5-methylcytidine from chromatin containing histone H3.3 TAS Mus musculus 61120 R-MMU-9821987 https://reactome.org/PathwayBrowser/#/R-MMU-9821987 Srpk1 phosphorylates Prm2 in Prm2:dsDNA TAS Mus musculus 61120 R-MMU-9821990 https://reactome.org/PathwayBrowser/#/R-MMU-9821990 Srpk1 phosphorylates Prm1 in Prm1:dsDNA TAS Mus musculus 61120 R-MMU-9822106 https://reactome.org/PathwayBrowser/#/R-MMU-9822106 Npm2 and Hira bind p-S9,S43-Prm1:dsDNA TAS Mus musculus 61120 R-MMU-9822114 https://reactome.org/PathwayBrowser/#/R-MMU-9822114 Npm2 dissociates p-S9,S43-Prm1 from Hira:Npm2:p-S9,S43-Prm1:dsDNA TAS Mus musculus 61120 R-MMU-9822208 https://reactome.org/PathwayBrowser/#/R-MMU-9822208 Hira and Npm2 assemble H3.3-containing nucleosomes on paternal DNA TAS Mus musculus 61120 R-MMU-996727 https://reactome.org/PathwayBrowser/#/R-MMU-996727 REST recruits the BHC complex IEA Mus musculus 61120 R-PFA-111264 https://reactome.org/PathwayBrowser/#/R-PFA-111264 Addition of nucleotides between position +11 and +30 IEA Plasmodium falciparum 61120 R-PFA-113430 https://reactome.org/PathwayBrowser/#/R-PFA-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Plasmodium falciparum 61120 R-PFA-113504 https://reactome.org/PathwayBrowser/#/R-PFA-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Plasmodium falciparum 61120 R-PFA-163296 https://reactome.org/PathwayBrowser/#/R-PFA-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Plasmodium falciparum 61120 R-PFA-163310 https://reactome.org/PathwayBrowser/#/R-PFA-163310 TFAM binds to mitochondrial promoters IEA Plasmodium falciparum 61120 R-PFA-176101 https://reactome.org/PathwayBrowser/#/R-PFA-176101 Recruitment of Rad17-RFC complex to DNA IEA Plasmodium falciparum 61120 R-PFA-176175 https://reactome.org/PathwayBrowser/#/R-PFA-176175 Stalling of DNA replication fork and RPA binding IEA Plasmodium falciparum 61120 R-PFA-5690213 https://reactome.org/PathwayBrowser/#/R-PFA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Plasmodium falciparum 61120 R-PFA-5690990 https://reactome.org/PathwayBrowser/#/R-PFA-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Plasmodium falciparum 61120 R-PFA-5690996 https://reactome.org/PathwayBrowser/#/R-PFA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Plasmodium falciparum 61120 R-PFA-5691001 https://reactome.org/PathwayBrowser/#/R-PFA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Plasmodium falciparum 61120 R-PFA-5693549 https://reactome.org/PathwayBrowser/#/R-PFA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Plasmodium falciparum 61120 R-PFA-5696655 https://reactome.org/PathwayBrowser/#/R-PFA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Plasmodium falciparum 61120 R-PFA-6781824 https://reactome.org/PathwayBrowser/#/R-PFA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Plasmodium falciparum 61120 R-PFA-6781867 https://reactome.org/PathwayBrowser/#/R-PFA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Plasmodium falciparum 61120 R-PFA-6782204 https://reactome.org/PathwayBrowser/#/R-PFA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Plasmodium falciparum 61120 R-PFA-6782208 https://reactome.org/PathwayBrowser/#/R-PFA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Plasmodium falciparum 61120 R-PFA-6782211 https://reactome.org/PathwayBrowser/#/R-PFA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Plasmodium falciparum 61120 R-PFA-6782943 https://reactome.org/PathwayBrowser/#/R-PFA-6782943 UV-DDB ubiquitinates XPC IEA Plasmodium falciparum 61120 R-PFA-68913 https://reactome.org/PathwayBrowser/#/R-PFA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Plasmodium falciparum 61120 R-PFA-68914 https://reactome.org/PathwayBrowser/#/R-PFA-68914 DNA polymerase alpha:primase binds at the origin IEA Plasmodium falciparum 61120 R-PFA-68950 https://reactome.org/PathwayBrowser/#/R-PFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Plasmodium falciparum 61120 R-PFA-68960 https://reactome.org/PathwayBrowser/#/R-PFA-68960 DNA polymerase epsilon binds at the origin IEA Plasmodium falciparum 61120 R-PFA-69053 https://reactome.org/PathwayBrowser/#/R-PFA-69053 RFC binding displaces Pol Alpha IEA Plasmodium falciparum 61120 R-PFA-69063 https://reactome.org/PathwayBrowser/#/R-PFA-69063 Loading of PCNA - Sliding Clamp Formation IEA Plasmodium falciparum 61120 R-PFA-69068 https://reactome.org/PathwayBrowser/#/R-PFA-69068 RFC dissociates after sliding clamp formation IEA Plasmodium falciparum 61120 R-PFA-69127 https://reactome.org/PathwayBrowser/#/R-PFA-69127 Formation of the Flap Intermediate IEA Plasmodium falciparum 61120 R-PFA-69140 https://reactome.org/PathwayBrowser/#/R-PFA-69140 RPA binds to the Flap IEA Plasmodium falciparum 61120 R-PFA-69152 https://reactome.org/PathwayBrowser/#/R-PFA-69152 Removal of remaining Flap IEA Plasmodium falciparum 61120 R-PFA-69173 https://reactome.org/PathwayBrowser/#/R-PFA-69173 Joining of adjacent Okazaki fragments IEA Plasmodium falciparum 61120 R-PFA-76576 https://reactome.org/PathwayBrowser/#/R-PFA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Plasmodium falciparum 61120 R-PFA-77068 https://reactome.org/PathwayBrowser/#/R-PFA-77068 Activation of GT IEA Plasmodium falciparum 61120 R-PFA-77071 https://reactome.org/PathwayBrowser/#/R-PFA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Plasmodium falciparum 61120 R-PFA-77073 https://reactome.org/PathwayBrowser/#/R-PFA-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Plasmodium falciparum 61120 R-PFA-77077 https://reactome.org/PathwayBrowser/#/R-PFA-77077 Capping complex formation IEA Plasmodium falciparum 61120 R-PFA-77078 https://reactome.org/PathwayBrowser/#/R-PFA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Plasmodium falciparum 61120 R-PFA-77081 https://reactome.org/PathwayBrowser/#/R-PFA-77081 Formation of the CE:GMP intermediate complex IEA Plasmodium falciparum 61120 R-PFA-77083 https://reactome.org/PathwayBrowser/#/R-PFA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Plasmodium falciparum 61120 R-PFA-77085 https://reactome.org/PathwayBrowser/#/R-PFA-77085 Dissociation of transcript with 5'-GMP from GT IEA Plasmodium falciparum 61120 R-RNO-1008200 https://reactome.org/PathwayBrowser/#/R-RNO-1008200 NFE2 binds the beta globin locus control region IEA Rattus norvegicus 61120 R-RNO-109636 https://reactome.org/PathwayBrowser/#/R-RNO-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Rattus norvegicus 61120 R-RNO-109637 https://reactome.org/PathwayBrowser/#/R-RNO-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Rattus norvegicus 61120 R-RNO-109638 https://reactome.org/PathwayBrowser/#/R-RNO-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Rattus norvegicus 61120 R-RNO-109639 https://reactome.org/PathwayBrowser/#/R-RNO-109639 Formation of the closed pre-initiation complex IEA Rattus norvegicus 61120 R-RNO-109699 https://reactome.org/PathwayBrowser/#/R-RNO-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Rattus norvegicus 61120 R-RNO-111264 https://reactome.org/PathwayBrowser/#/R-RNO-111264 Addition of nucleotides between position +11 and +30 IEA Rattus norvegicus 61120 R-RNO-112379 https://reactome.org/PathwayBrowser/#/R-RNO-112379 Recruitment of elongation factors to form elongation complex IEA Rattus norvegicus 61120 R-RNO-112381 https://reactome.org/PathwayBrowser/#/R-RNO-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Rattus norvegicus 61120 R-RNO-112385 https://reactome.org/PathwayBrowser/#/R-RNO-112385 Addition of nucleotides leads to transcript elongation IEA Rattus norvegicus 61120 R-RNO-113429 https://reactome.org/PathwayBrowser/#/R-RNO-113429 Elongating transcript encounters a lesion in the template IEA Rattus norvegicus 61120 R-RNO-113430 https://reactome.org/PathwayBrowser/#/R-RNO-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Rattus norvegicus 61120 R-RNO-113503 https://reactome.org/PathwayBrowser/#/R-RNO-113503 PP2A mediated localization of RB1 protein in chromatin IEA Rattus norvegicus 61120 R-RNO-113504 https://reactome.org/PathwayBrowser/#/R-RNO-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Rattus norvegicus 61120 R-RNO-1535903 https://reactome.org/PathwayBrowser/#/R-RNO-1535903 Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements IEA Rattus norvegicus 61120 R-RNO-163296 https://reactome.org/PathwayBrowser/#/R-RNO-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Rattus norvegicus 61120 R-RNO-163310 https://reactome.org/PathwayBrowser/#/R-RNO-163310 TFAM binds to mitochondrial promoters IEA Rattus norvegicus 61120 R-RNO-163320 https://reactome.org/PathwayBrowser/#/R-RNO-163320 Association of mTERF with the termination sequence IEA Rattus norvegicus 61120 R-RNO-1679098 https://reactome.org/PathwayBrowser/#/R-RNO-1679098 Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer IEA Rattus norvegicus 61120 R-RNO-1679589 https://reactome.org/PathwayBrowser/#/R-RNO-1679589 Engulfed CpG DNA binds to endosomal full-length TLR9 IEA Rattus norvegicus 61120 R-RNO-174427 https://reactome.org/PathwayBrowser/#/R-RNO-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Rattus norvegicus 61120 R-RNO-174438 https://reactome.org/PathwayBrowser/#/R-RNO-174438 Formation of the Flap Intermediate on the C-strand IEA Rattus norvegicus 61120 R-RNO-174439 https://reactome.org/PathwayBrowser/#/R-RNO-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Rattus norvegicus 61120 R-RNO-174441 https://reactome.org/PathwayBrowser/#/R-RNO-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Rattus norvegicus 61120 R-RNO-174444 https://reactome.org/PathwayBrowser/#/R-RNO-174444 Formation of C-strand Okazaki fragments IEA Rattus norvegicus 61120 R-RNO-174445 https://reactome.org/PathwayBrowser/#/R-RNO-174445 RPA binds to the Flap on the C-strand IEA Rattus norvegicus 61120 R-RNO-174446 https://reactome.org/PathwayBrowser/#/R-RNO-174446 Removal of remaining Flap from the C-strand IEA Rattus norvegicus 61120 R-RNO-174447 https://reactome.org/PathwayBrowser/#/R-RNO-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Rattus norvegicus 61120 R-RNO-174448 https://reactome.org/PathwayBrowser/#/R-RNO-174448 Formation of Processive Complex on the C-strand of the telomere IEA Rattus norvegicus 61120 R-RNO-174451 https://reactome.org/PathwayBrowser/#/R-RNO-174451 Recruitment of DNA2 endonuclease to the C strand IEA Rattus norvegicus 61120 R-RNO-174452 https://reactome.org/PathwayBrowser/#/R-RNO-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Rattus norvegicus 61120 R-RNO-174456 https://reactome.org/PathwayBrowser/#/R-RNO-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Rattus norvegicus 61120 R-RNO-176101 https://reactome.org/PathwayBrowser/#/R-RNO-176101 Recruitment of Rad17-RFC complex to DNA IEA Rattus norvegicus 61120 R-RNO-176175 https://reactome.org/PathwayBrowser/#/R-RNO-176175 Stalling of DNA replication fork and RPA binding IEA Rattus norvegicus 61120 R-RNO-176250 https://reactome.org/PathwayBrowser/#/R-RNO-176250 Binding of ATR-ATRIP to the RPA-ssDNA complex IEA Rattus norvegicus 61120 R-RNO-176264 https://reactome.org/PathwayBrowser/#/R-RNO-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Rattus norvegicus 61120 R-RNO-187895 https://reactome.org/PathwayBrowser/#/R-RNO-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 IEA Rattus norvegicus 61120 R-RNO-188002 https://reactome.org/PathwayBrowser/#/R-RNO-188002 Rab5-mediated recruitment of class III PI3K to TLR9 IEA Rattus norvegicus 61120 R-RNO-211247 https://reactome.org/PathwayBrowser/#/R-RNO-211247 Cleavage of DNA by DFF40 IEA Rattus norvegicus 61120 R-RNO-2247510 https://reactome.org/PathwayBrowser/#/R-RNO-2247510 MARCO:ligand is endocytosed IEA Rattus norvegicus 61120 R-RNO-3134883 https://reactome.org/PathwayBrowser/#/R-RNO-3134883 Beta-catenin enhances association of IRF3 with CBP/p300 IEA Rattus norvegicus 61120 R-RNO-3134953 https://reactome.org/PathwayBrowser/#/R-RNO-3134953 DHX36 or DHX9 binds MyD88 IEA Rattus norvegicus 61120 R-RNO-3134954 https://reactome.org/PathwayBrowser/#/R-RNO-3134954 DHX9 binds DNA IEA Rattus norvegicus 61120 R-RNO-3134962 https://reactome.org/PathwayBrowser/#/R-RNO-3134962 DHX36 binds DNA IEA Rattus norvegicus 61120 R-RNO-3785711 https://reactome.org/PathwayBrowser/#/R-RNO-3785711 Telomere shortening during replicative exhaustion IEA Rattus norvegicus 61120 R-RNO-3785768 https://reactome.org/PathwayBrowser/#/R-RNO-3785768 MRN complex binds DNA double strand breaks IEA Rattus norvegicus 61120 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus 61120 R-RNO-400183 https://reactome.org/PathwayBrowser/#/R-RNO-400183 PPARA:RXRA binds Corepressors of PPARA IEA Rattus norvegicus 61120 R-RNO-400204 https://reactome.org/PathwayBrowser/#/R-RNO-400204 PPARA binds RXRA IEA Rattus norvegicus 61120 R-RNO-5250930 https://reactome.org/PathwayBrowser/#/R-RNO-5250930 B-WICH recruits histone acetyltransferases IEA Rattus norvegicus 61120 R-RNO-5250938 https://reactome.org/PathwayBrowser/#/R-RNO-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Rattus norvegicus 61120 R-RNO-5250947 https://reactome.org/PathwayBrowser/#/R-RNO-5250947 B-WICH complex binds rDNA promoter IEA Rattus norvegicus 61120 R-RNO-5682018 https://reactome.org/PathwayBrowser/#/R-RNO-5682018 MRN complex bound to shortened telomeres recruits ATM IEA Rattus norvegicus 61120 R-RNO-5682020 https://reactome.org/PathwayBrowser/#/R-RNO-5682020 MRN complex binds shortened telomeres IEA Rattus norvegicus 61120 R-RNO-5682026 https://reactome.org/PathwayBrowser/#/R-RNO-5682026 MRN bound to shortened telomeres activates ATM IEA Rattus norvegicus 61120 R-RNO-5682044 https://reactome.org/PathwayBrowser/#/R-RNO-5682044 KAT5 acetylates ATM at DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5682586 https://reactome.org/PathwayBrowser/#/R-RNO-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5682588 https://reactome.org/PathwayBrowser/#/R-RNO-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5682598 https://reactome.org/PathwayBrowser/#/R-RNO-5682598 ATM phosphorylates HERC2 IEA Rattus norvegicus 61120 R-RNO-5682607 https://reactome.org/PathwayBrowser/#/R-RNO-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5682858 https://reactome.org/PathwayBrowser/#/R-RNO-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Rattus norvegicus 61120 R-RNO-5682863 https://reactome.org/PathwayBrowser/#/R-RNO-5682863 RNF168 binds DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5682965 https://reactome.org/PathwayBrowser/#/R-RNO-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Rattus norvegicus 61120 R-RNO-5682967 https://reactome.org/PathwayBrowser/#/R-RNO-5682967 WHSC1 binds DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5682983 https://reactome.org/PathwayBrowser/#/R-RNO-5682983 ATM phosphorylates WHSC1 IEA Rattus norvegicus 61120 R-RNO-5682992 https://reactome.org/PathwayBrowser/#/R-RNO-5682992 KDM4A,B bind H4K20Me2 IEA Rattus norvegicus 61120 R-RNO-5683077 https://reactome.org/PathwayBrowser/#/R-RNO-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Rattus norvegicus 61120 R-RNO-5683384 https://reactome.org/PathwayBrowser/#/R-RNO-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5683385 https://reactome.org/PathwayBrowser/#/R-RNO-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5683405 https://reactome.org/PathwayBrowser/#/R-RNO-5683405 PPP5C dephosphorylates TP53BP1 IEA Rattus norvegicus 61120 R-RNO-5683425 https://reactome.org/PathwayBrowser/#/R-RNO-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5683735 https://reactome.org/PathwayBrowser/#/R-RNO-5683735 CHEK2 is recruited to DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5683801 https://reactome.org/PathwayBrowser/#/R-RNO-5683801 CHEK2 phosphorylates BRCA1 IEA Rattus norvegicus 61120 R-RNO-5683964 https://reactome.org/PathwayBrowser/#/R-RNO-5683964 ATM phosphorylates EYA1-4 IEA Rattus norvegicus 61120 R-RNO-5683967 https://reactome.org/PathwayBrowser/#/R-RNO-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Rattus norvegicus 61120 R-RNO-5683986 https://reactome.org/PathwayBrowser/#/R-RNO-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA Rattus norvegicus 61120 R-RNO-5684052 https://reactome.org/PathwayBrowser/#/R-RNO-5684052 PIAS4 SUMOylates MDC1 IEA Rattus norvegicus 61120 R-RNO-5684081 https://reactome.org/PathwayBrowser/#/R-RNO-5684081 MRN complex binds CDK2 and RBBP8 IEA Rattus norvegicus 61120 R-RNO-5684096 https://reactome.org/PathwayBrowser/#/R-RNO-5684096 CDK2 phosphorylates RBBP8 IEA Rattus norvegicus 61120 R-RNO-5684108 https://reactome.org/PathwayBrowser/#/R-RNO-5684108 BRCA1 binds phosphorylated RBBP8 IEA Rattus norvegicus 61120 R-RNO-5684140 https://reactome.org/PathwayBrowser/#/R-RNO-5684140 ATM phosphorylates RBBP8 IEA Rattus norvegicus 61120 R-RNO-5684875 https://reactome.org/PathwayBrowser/#/R-RNO-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5684882 https://reactome.org/PathwayBrowser/#/R-RNO-5684882 CHEK1 is recruited to resected DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5684887 https://reactome.org/PathwayBrowser/#/R-RNO-5684887 Activation of CHEK1 at resected DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5685011 https://reactome.org/PathwayBrowser/#/R-RNO-5685011 ATR activation at DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5685156 https://reactome.org/PathwayBrowser/#/R-RNO-5685156 ATR phosphorylates RPA2 IEA Rattus norvegicus 61120 R-RNO-5685341 https://reactome.org/PathwayBrowser/#/R-RNO-5685341 BCDX2 complex stabilizes RAD51 filament IEA Rattus norvegicus 61120 R-RNO-5685838 https://reactome.org/PathwayBrowser/#/R-RNO-5685838 CX3 complex binds D-loop structures IEA Rattus norvegicus 61120 R-RNO-5685985 https://reactome.org/PathwayBrowser/#/R-RNO-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Rattus norvegicus 61120 R-RNO-5685994 https://reactome.org/PathwayBrowser/#/R-RNO-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Rattus norvegicus 61120 R-RNO-5686440 https://reactome.org/PathwayBrowser/#/R-RNO-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Rattus norvegicus 61120 R-RNO-5686642 https://reactome.org/PathwayBrowser/#/R-RNO-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5686657 https://reactome.org/PathwayBrowser/#/R-RNO-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Rattus norvegicus 61120 R-RNO-5686685 https://reactome.org/PathwayBrowser/#/R-RNO-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5686704 https://reactome.org/PathwayBrowser/#/R-RNO-5686704 Activated ATM phosphorylates DCLRE1C IEA Rattus norvegicus 61120 R-RNO-5686900 https://reactome.org/PathwayBrowser/#/R-RNO-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Rattus norvegicus 61120 R-RNO-5686924 https://reactome.org/PathwayBrowser/#/R-RNO-5686924 DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5687183 https://reactome.org/PathwayBrowser/#/R-RNO-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5687360 https://reactome.org/PathwayBrowser/#/R-RNO-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Rattus norvegicus 61120 R-RNO-5687464 https://reactome.org/PathwayBrowser/#/R-RNO-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Rattus norvegicus 61120 R-RNO-5687465 https://reactome.org/PathwayBrowser/#/R-RNO-5687465 MRN complex binds RBBP8 IEA Rattus norvegicus 61120 R-RNO-5687484 https://reactome.org/PathwayBrowser/#/R-RNO-5687484 PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site IEA Rattus norvegicus 61120 R-RNO-5687640 https://reactome.org/PathwayBrowser/#/R-RNO-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Rattus norvegicus 61120 R-RNO-5687653 https://reactome.org/PathwayBrowser/#/R-RNO-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Rattus norvegicus 61120 R-RNO-5687664 https://reactome.org/PathwayBrowser/#/R-RNO-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Rattus norvegicus 61120 R-RNO-5687673 https://reactome.org/PathwayBrowser/#/R-RNO-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites IEA Rattus norvegicus 61120 R-RNO-5687675 https://reactome.org/PathwayBrowser/#/R-RNO-5687675 LIG3 ligates remaining SSBs in MMEJ IEA Rattus norvegicus 61120 R-RNO-5689317 https://reactome.org/PathwayBrowser/#/R-RNO-5689317 Formation of the pre-incision complex in GG-NER IEA Rattus norvegicus 61120 R-RNO-5689861 https://reactome.org/PathwayBrowser/#/R-RNO-5689861 Recruitment of XPA and release of CAK IEA Rattus norvegicus 61120 R-RNO-5690213 https://reactome.org/PathwayBrowser/#/R-RNO-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Rattus norvegicus 61120 R-RNO-5690988 https://reactome.org/PathwayBrowser/#/R-RNO-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Rattus norvegicus 61120 R-RNO-5690990 https://reactome.org/PathwayBrowser/#/R-RNO-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Rattus norvegicus 61120 R-RNO-5690991 https://reactome.org/PathwayBrowser/#/R-RNO-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Rattus norvegicus 61120 R-RNO-5690996 https://reactome.org/PathwayBrowser/#/R-RNO-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Rattus norvegicus 61120 R-RNO-5691000 https://reactome.org/PathwayBrowser/#/R-RNO-5691000 TFIIH binds GG-NER site to form a verification complex IEA Rattus norvegicus 61120 R-RNO-5691001 https://reactome.org/PathwayBrowser/#/R-RNO-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Rattus norvegicus 61120 R-RNO-5691006 https://reactome.org/PathwayBrowser/#/R-RNO-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Rattus norvegicus 61120 R-RNO-5693533 https://reactome.org/PathwayBrowser/#/R-RNO-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends IEA Rattus norvegicus 61120 R-RNO-5693536 https://reactome.org/PathwayBrowser/#/R-RNO-5693536 ATM phosphorylates MDC1 IEA Rattus norvegicus 61120 R-RNO-5693539 https://reactome.org/PathwayBrowser/#/R-RNO-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Rattus norvegicus 61120 R-RNO-5693540 https://reactome.org/PathwayBrowser/#/R-RNO-5693540 MRN activates ATM IEA Rattus norvegicus 61120 R-RNO-5693542 https://reactome.org/PathwayBrowser/#/R-RNO-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5693549 https://reactome.org/PathwayBrowser/#/R-RNO-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5693551 https://reactome.org/PathwayBrowser/#/R-RNO-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Rattus norvegicus 61120 R-RNO-5693564 https://reactome.org/PathwayBrowser/#/R-RNO-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Rattus norvegicus 61120 R-RNO-5693566 https://reactome.org/PathwayBrowser/#/R-RNO-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5693574 https://reactome.org/PathwayBrowser/#/R-RNO-5693574 XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ IEA Rattus norvegicus 61120 R-RNO-5693575 https://reactome.org/PathwayBrowser/#/R-RNO-5693575 DNA-PKcs autophosphorylates IEA Rattus norvegicus 61120 R-RNO-5693578 https://reactome.org/PathwayBrowser/#/R-RNO-5693578 TDP1 and TDP2 process unligatable DSB ends IEA Rattus norvegicus 61120 R-RNO-5693580 https://reactome.org/PathwayBrowser/#/R-RNO-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Rattus norvegicus 61120 R-RNO-5693583 https://reactome.org/PathwayBrowser/#/R-RNO-5693583 MDC1 associates with gamma-H2AFX at nuclear foci IEA Rattus norvegicus 61120 R-RNO-5693584 https://reactome.org/PathwayBrowser/#/R-RNO-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Rattus norvegicus 61120 R-RNO-5693593 https://reactome.org/PathwayBrowser/#/R-RNO-5693593 D-loop extension by DNA polymerases IEA Rattus norvegicus 61120 R-RNO-5693598 https://reactome.org/PathwayBrowser/#/R-RNO-5693598 ATM phosphorylates NBN IEA Rattus norvegicus 61120 R-RNO-5693602 https://reactome.org/PathwayBrowser/#/R-RNO-5693602 ATM recognizes H2AFX-Nucleosomes IEA Rattus norvegicus 61120 R-RNO-5693608 https://reactome.org/PathwayBrowser/#/R-RNO-5693608 Initial resection of double-strand break ends IEA Rattus norvegicus 61120 R-RNO-5693612 https://reactome.org/PathwayBrowser/#/R-RNO-5693612 MRN complex bound to DNA ends recruits ATM IEA Rattus norvegicus 61120 R-RNO-5693615 https://reactome.org/PathwayBrowser/#/R-RNO-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis IEA Rattus norvegicus 61120 R-RNO-5693620 https://reactome.org/PathwayBrowser/#/R-RNO-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Rattus norvegicus 61120 R-RNO-5696655 https://reactome.org/PathwayBrowser/#/R-RNO-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Rattus norvegicus 61120 R-RNO-5696664 https://reactome.org/PathwayBrowser/#/R-RNO-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Rattus norvegicus 61120 R-RNO-5696670 https://reactome.org/PathwayBrowser/#/R-RNO-5696670 CHD1L is recruited to GG-NER site IEA Rattus norvegicus 61120 R-RNO-6781818 https://reactome.org/PathwayBrowser/#/R-RNO-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Rattus norvegicus 61120 R-RNO-6781824 https://reactome.org/PathwayBrowser/#/R-RNO-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Rattus norvegicus 61120 R-RNO-6781833 https://reactome.org/PathwayBrowser/#/R-RNO-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Rattus norvegicus 61120 R-RNO-6781840 https://reactome.org/PathwayBrowser/#/R-RNO-6781840 ERCC6 binds stalled RNA Pol II IEA Rattus norvegicus 61120 R-RNO-6781867 https://reactome.org/PathwayBrowser/#/R-RNO-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Rattus norvegicus 61120 R-RNO-6782004 https://reactome.org/PathwayBrowser/#/R-RNO-6782004 Assembly of the pre-incision complex in TC-NER IEA Rattus norvegicus 61120 R-RNO-6782069 https://reactome.org/PathwayBrowser/#/R-RNO-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Rattus norvegicus 61120 R-RNO-6782131 https://reactome.org/PathwayBrowser/#/R-RNO-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus 61120 R-RNO-6782138 https://reactome.org/PathwayBrowser/#/R-RNO-6782138 ERCC5 and RPA bind TC-NER site IEA Rattus norvegicus 61120 R-RNO-6782141 https://reactome.org/PathwayBrowser/#/R-RNO-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Rattus norvegicus 61120 R-RNO-6782204 https://reactome.org/PathwayBrowser/#/R-RNO-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Rattus norvegicus 61120 R-RNO-6782208 https://reactome.org/PathwayBrowser/#/R-RNO-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Rattus norvegicus 61120 R-RNO-6782211 https://reactome.org/PathwayBrowser/#/R-RNO-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Rattus norvegicus 61120 R-RNO-6782224 https://reactome.org/PathwayBrowser/#/R-RNO-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Rattus norvegicus 61120 R-RNO-6782227 https://reactome.org/PathwayBrowser/#/R-RNO-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Rattus norvegicus 61120 R-RNO-6782943 https://reactome.org/PathwayBrowser/#/R-RNO-6782943 UV-DDB ubiquitinates XPC IEA Rattus norvegicus 61120 R-RNO-6786166 https://reactome.org/PathwayBrowser/#/R-RNO-6786166 Translesion synthesis across unhooked ICL by POLN IEA Rattus norvegicus 61120 R-RNO-6790454 https://reactome.org/PathwayBrowser/#/R-RNO-6790454 SUMOylation of XPC IEA Rattus norvegicus 61120 R-RNO-6792712 https://reactome.org/PathwayBrowser/#/R-RNO-6792712 KAT5 acetylates ATM at shortened telomeres IEA Rattus norvegicus 61120 R-RNO-6799332 https://reactome.org/PathwayBrowser/#/R-RNO-6799332 ATR phosphorylates TP53 IEA Rattus norvegicus 61120 R-RNO-68913 https://reactome.org/PathwayBrowser/#/R-RNO-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Rattus norvegicus 61120 R-RNO-68914 https://reactome.org/PathwayBrowser/#/R-RNO-68914 DNA polymerase alpha:primase binds at the origin IEA Rattus norvegicus 61120 R-RNO-68944 https://reactome.org/PathwayBrowser/#/R-RNO-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Rattus norvegicus 61120 R-RNO-68950 https://reactome.org/PathwayBrowser/#/R-RNO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Rattus norvegicus 61120 R-RNO-68960 https://reactome.org/PathwayBrowser/#/R-RNO-68960 DNA polymerase epsilon binds at the origin IEA Rattus norvegicus 61120 R-RNO-69053 https://reactome.org/PathwayBrowser/#/R-RNO-69053 RFC binding displaces Pol Alpha IEA Rattus norvegicus 61120 R-RNO-69063 https://reactome.org/PathwayBrowser/#/R-RNO-69063 Loading of PCNA - Sliding Clamp Formation IEA Rattus norvegicus 61120 R-RNO-69068 https://reactome.org/PathwayBrowser/#/R-RNO-69068 RFC dissociates after sliding clamp formation IEA Rattus norvegicus 61120 R-RNO-69074 https://reactome.org/PathwayBrowser/#/R-RNO-69074 Formation of Processive Complex IEA Rattus norvegicus 61120 R-RNO-69116 https://reactome.org/PathwayBrowser/#/R-RNO-69116 Formation of Okazaki fragments IEA Rattus norvegicus 61120 R-RNO-69127 https://reactome.org/PathwayBrowser/#/R-RNO-69127 Formation of the Flap Intermediate IEA Rattus norvegicus 61120 R-RNO-69140 https://reactome.org/PathwayBrowser/#/R-RNO-69140 RPA binds to the Flap IEA Rattus norvegicus 61120 R-RNO-69142 https://reactome.org/PathwayBrowser/#/R-RNO-69142 Recruitment of Dna2 endonuclease IEA Rattus norvegicus 61120 R-RNO-69144 https://reactome.org/PathwayBrowser/#/R-RNO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Rattus norvegicus 61120 R-RNO-69152 https://reactome.org/PathwayBrowser/#/R-RNO-69152 Removal of remaining Flap IEA Rattus norvegicus 61120 R-RNO-69173 https://reactome.org/PathwayBrowser/#/R-RNO-69173 Joining of adjacent Okazaki fragments IEA Rattus norvegicus 61120 R-RNO-69891 https://reactome.org/PathwayBrowser/#/R-RNO-69891 Phosphorylation and activation of CHEK2 by ATM IEA Rattus norvegicus 61120 R-RNO-73718 https://reactome.org/PathwayBrowser/#/R-RNO-73718 UBF-1 Binds rDNA Promoter IEA Rattus norvegicus 61120 R-RNO-73722 https://reactome.org/PathwayBrowser/#/R-RNO-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Rattus norvegicus 61120 R-RNO-73739 https://reactome.org/PathwayBrowser/#/R-RNO-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Rattus norvegicus 61120 R-RNO-73758 https://reactome.org/PathwayBrowser/#/R-RNO-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Rattus norvegicus 61120 R-RNO-73769 https://reactome.org/PathwayBrowser/#/R-RNO-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Rattus norvegicus 61120 R-RNO-73946 https://reactome.org/PathwayBrowser/#/R-RNO-73946 Abortive initiation after formation of the first phosphodiester bond IEA Rattus norvegicus 61120 R-RNO-75095 https://reactome.org/PathwayBrowser/#/R-RNO-75095 Binding of TFIIE to the growing preinitiation complex IEA Rattus norvegicus 61120 R-RNO-75850 https://reactome.org/PathwayBrowser/#/R-RNO-75850 Addition of the third nucleotide on the nascent transcript IEA Rattus norvegicus 61120 R-RNO-75856 https://reactome.org/PathwayBrowser/#/R-RNO-75856 Abortive Initiation Before Second Transition IEA Rattus norvegicus 61120 R-RNO-75861 https://reactome.org/PathwayBrowser/#/R-RNO-75861 NTP Binds Active Site of RNA Polymerase II IEA Rattus norvegicus 61120 R-RNO-75862 https://reactome.org/PathwayBrowser/#/R-RNO-75862 Fall Back to Closed Pre-initiation Complex IEA Rattus norvegicus 61120 R-RNO-75864 https://reactome.org/PathwayBrowser/#/R-RNO-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Rattus norvegicus 61120 R-RNO-75866 https://reactome.org/PathwayBrowser/#/R-RNO-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Rattus norvegicus 61120 R-RNO-75869 https://reactome.org/PathwayBrowser/#/R-RNO-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Rattus norvegicus 61120 R-RNO-75873 https://reactome.org/PathwayBrowser/#/R-RNO-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Rattus norvegicus 61120 R-RNO-75891 https://reactome.org/PathwayBrowser/#/R-RNO-75891 Abortive Initiation After Second Transition IEA Rattus norvegicus 61120 R-RNO-75949 https://reactome.org/PathwayBrowser/#/R-RNO-75949 RNA Polymerase II Promoter Opening: First Transition IEA Rattus norvegicus 61120 R-RNO-76052 https://reactome.org/PathwayBrowser/#/R-RNO-76052 Binding of TFIIIA To type 1 Promoter IEA Rattus norvegicus 61120 R-RNO-76054 https://reactome.org/PathwayBrowser/#/R-RNO-76054 Binding of TFIIIC to TFIIIA:Type I Promoter complex IEA Rattus norvegicus 61120 R-RNO-76056 https://reactome.org/PathwayBrowser/#/R-RNO-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Rattus norvegicus 61120 R-RNO-76576 https://reactome.org/PathwayBrowser/#/R-RNO-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Rattus norvegicus 61120 R-RNO-77068 https://reactome.org/PathwayBrowser/#/R-RNO-77068 Activation of GT IEA Rattus norvegicus 61120 R-RNO-77069 https://reactome.org/PathwayBrowser/#/R-RNO-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Rattus norvegicus 61120 R-RNO-77071 https://reactome.org/PathwayBrowser/#/R-RNO-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Rattus norvegicus 61120 R-RNO-77073 https://reactome.org/PathwayBrowser/#/R-RNO-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Rattus norvegicus 61120 R-RNO-77077 https://reactome.org/PathwayBrowser/#/R-RNO-77077 Capping complex formation IEA Rattus norvegicus 61120 R-RNO-77078 https://reactome.org/PathwayBrowser/#/R-RNO-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Rattus norvegicus 61120 R-RNO-77081 https://reactome.org/PathwayBrowser/#/R-RNO-77081 Formation of the CE:GMP intermediate complex IEA Rattus norvegicus 61120 R-RNO-77083 https://reactome.org/PathwayBrowser/#/R-RNO-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Rattus norvegicus 61120 R-RNO-77085 https://reactome.org/PathwayBrowser/#/R-RNO-77085 Dissociation of transcript with 5'-GMP from GT IEA Rattus norvegicus 61120 R-RNO-77090 https://reactome.org/PathwayBrowser/#/R-RNO-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Rattus norvegicus 61120 R-RNO-83723 https://reactome.org/PathwayBrowser/#/R-RNO-83723 Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex IEA Rattus norvegicus 61120 R-RNO-83788 https://reactome.org/PathwayBrowser/#/R-RNO-83788 Binding of TFIIIC to Type 2 promoter IEA Rattus norvegicus 61120 R-RNO-83790 https://reactome.org/PathwayBrowser/#/R-RNO-83790 Binding of TFIIIB to TFIIC: Type 2 Promoter Complex IEA Rattus norvegicus 61120 R-RNO-83803 https://reactome.org/PathwayBrowser/#/R-RNO-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Rattus norvegicus 61120 R-RNO-83805 https://reactome.org/PathwayBrowser/#/R-RNO-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Rattus norvegicus 61120 R-RNO-9604480 https://reactome.org/PathwayBrowser/#/R-RNO-9604480 NFkB complex translocates from the cytosol to the nucleus IEA Rattus norvegicus 61120 R-RNO-9604487 https://reactome.org/PathwayBrowser/#/R-RNO-9604487 p-IRF7:p-IRF7 translocates to the nucleus IEA Rattus norvegicus 61120 R-RNO-9613494 https://reactome.org/PathwayBrowser/#/R-RNO-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Rattus norvegicus 61120 R-RNO-9613497 https://reactome.org/PathwayBrowser/#/R-RNO-9613497 Unwinding DNA for the nascent transcript IEA Rattus norvegicus 61120 R-RNO-9684118 https://reactome.org/PathwayBrowser/#/R-RNO-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus 61120 R-RNO-9734475 https://reactome.org/PathwayBrowser/#/R-RNO-9734475 PPARA binds fibrates IEA Rattus norvegicus 61120 R-RNO-996727 https://reactome.org/PathwayBrowser/#/R-RNO-996727 REST recruits the BHC complex IEA Rattus norvegicus 61120 R-SCE-109636 https://reactome.org/PathwayBrowser/#/R-SCE-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Saccharomyces cerevisiae 61120 R-SCE-109637 https://reactome.org/PathwayBrowser/#/R-SCE-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Saccharomyces cerevisiae 61120 R-SCE-109638 https://reactome.org/PathwayBrowser/#/R-SCE-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Saccharomyces cerevisiae 61120 R-SCE-109639 https://reactome.org/PathwayBrowser/#/R-SCE-109639 Formation of the closed pre-initiation complex IEA Saccharomyces cerevisiae 61120 R-SCE-111264 https://reactome.org/PathwayBrowser/#/R-SCE-111264 Addition of nucleotides between position +11 and +30 IEA Saccharomyces cerevisiae 61120 R-SCE-113430 https://reactome.org/PathwayBrowser/#/R-SCE-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Saccharomyces cerevisiae 61120 R-SCE-113504 https://reactome.org/PathwayBrowser/#/R-SCE-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Saccharomyces cerevisiae 61120 R-SCE-163296 https://reactome.org/PathwayBrowser/#/R-SCE-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Saccharomyces cerevisiae 61120 R-SCE-163310 https://reactome.org/PathwayBrowser/#/R-SCE-163310 TFAM binds to mitochondrial promoters IEA Saccharomyces cerevisiae 61120 R-SCE-169439 https://reactome.org/PathwayBrowser/#/R-SCE-169439 Yeast Mcm2-7 mediated fork unwinding TAS Saccharomyces cerevisiae 61120 R-SCE-176264 https://reactome.org/PathwayBrowser/#/R-SCE-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Saccharomyces cerevisiae 61120 R-SCE-5682026 https://reactome.org/PathwayBrowser/#/R-SCE-5682026 MRN bound to shortened telomeres activates ATM IEA Saccharomyces cerevisiae 61120 R-SCE-5682044 https://reactome.org/PathwayBrowser/#/R-SCE-5682044 KAT5 acetylates ATM at DNA DSBs IEA Saccharomyces cerevisiae 61120 R-SCE-5682588 https://reactome.org/PathwayBrowser/#/R-SCE-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Saccharomyces cerevisiae 61120 R-SCE-5682598 https://reactome.org/PathwayBrowser/#/R-SCE-5682598 ATM phosphorylates HERC2 IEA Saccharomyces cerevisiae 61120 R-SCE-5682607 https://reactome.org/PathwayBrowser/#/R-SCE-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Saccharomyces cerevisiae 61120 R-SCE-5682629 https://reactome.org/PathwayBrowser/#/R-SCE-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Saccharomyces cerevisiae 61120 R-SCE-5682858 https://reactome.org/PathwayBrowser/#/R-SCE-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Saccharomyces cerevisiae 61120 R-SCE-5682965 https://reactome.org/PathwayBrowser/#/R-SCE-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Saccharomyces cerevisiae 61120 R-SCE-5682967 https://reactome.org/PathwayBrowser/#/R-SCE-5682967 WHSC1 binds DNA DSBs IEA Saccharomyces cerevisiae 61120 R-SCE-5682983 https://reactome.org/PathwayBrowser/#/R-SCE-5682983 ATM phosphorylates WHSC1 IEA Saccharomyces cerevisiae 61120 R-SCE-5682992 https://reactome.org/PathwayBrowser/#/R-SCE-5682992 KDM4A,B bind H4K20Me2 IEA Saccharomyces cerevisiae 61120 R-SCE-5683077 https://reactome.org/PathwayBrowser/#/R-SCE-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Saccharomyces cerevisiae 61120 R-SCE-5683405 https://reactome.org/PathwayBrowser/#/R-SCE-5683405 PPP5C dephosphorylates TP53BP1 IEA Saccharomyces cerevisiae 61120 R-SCE-5683425 https://reactome.org/PathwayBrowser/#/R-SCE-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Saccharomyces cerevisiae 61120 R-SCE-5691001 https://reactome.org/PathwayBrowser/#/R-SCE-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Saccharomyces cerevisiae 61120 R-SCE-5693536 https://reactome.org/PathwayBrowser/#/R-SCE-5693536 ATM phosphorylates MDC1 IEA Saccharomyces cerevisiae 61120 R-SCE-5693540 https://reactome.org/PathwayBrowser/#/R-SCE-5693540 MRN activates ATM IEA Saccharomyces cerevisiae 61120 R-SCE-5693549 https://reactome.org/PathwayBrowser/#/R-SCE-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Saccharomyces cerevisiae 61120 R-SCE-5693566 https://reactome.org/PathwayBrowser/#/R-SCE-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Saccharomyces cerevisiae 61120 R-SCE-5693598 https://reactome.org/PathwayBrowser/#/R-SCE-5693598 ATM phosphorylates NBN IEA Saccharomyces cerevisiae 61120 R-SCE-5693602 https://reactome.org/PathwayBrowser/#/R-SCE-5693602 ATM recognizes H2AFX-Nucleosomes IEA Saccharomyces cerevisiae 61120 R-SCE-6781818 https://reactome.org/PathwayBrowser/#/R-SCE-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Saccharomyces cerevisiae 61120 R-SCE-6781824 https://reactome.org/PathwayBrowser/#/R-SCE-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Saccharomyces cerevisiae 61120 R-SCE-6781840 https://reactome.org/PathwayBrowser/#/R-SCE-6781840 ERCC6 binds stalled RNA Pol II IEA Saccharomyces cerevisiae 61120 R-SCE-6781867 https://reactome.org/PathwayBrowser/#/R-SCE-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Saccharomyces cerevisiae 61120 R-SCE-6782069 https://reactome.org/PathwayBrowser/#/R-SCE-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Saccharomyces cerevisiae 61120 R-SCE-6782131 https://reactome.org/PathwayBrowser/#/R-SCE-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Saccharomyces cerevisiae 61120 R-SCE-6782204 https://reactome.org/PathwayBrowser/#/R-SCE-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Saccharomyces cerevisiae 61120 R-SCE-6782208 https://reactome.org/PathwayBrowser/#/R-SCE-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Saccharomyces cerevisiae 61120 R-SCE-6782211 https://reactome.org/PathwayBrowser/#/R-SCE-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Saccharomyces cerevisiae 61120 R-SCE-6782227 https://reactome.org/PathwayBrowser/#/R-SCE-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Saccharomyces cerevisiae 61120 R-SCE-6792712 https://reactome.org/PathwayBrowser/#/R-SCE-6792712 KAT5 acetylates ATM at shortened telomeres IEA Saccharomyces cerevisiae 61120 R-SCE-68913 https://reactome.org/PathwayBrowser/#/R-SCE-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Saccharomyces cerevisiae 61120 R-SCE-68914 https://reactome.org/PathwayBrowser/#/R-SCE-68914 DNA polymerase alpha:primase binds at the origin IEA Saccharomyces cerevisiae 61120 R-SCE-68950 https://reactome.org/PathwayBrowser/#/R-SCE-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Saccharomyces cerevisiae 61120 R-SCE-68960 https://reactome.org/PathwayBrowser/#/R-SCE-68960 DNA polymerase epsilon binds at the origin IEA Saccharomyces cerevisiae 61120 R-SCE-69053 https://reactome.org/PathwayBrowser/#/R-SCE-69053 RFC binding displaces Pol Alpha IEA Saccharomyces cerevisiae 61120 R-SCE-69063 https://reactome.org/PathwayBrowser/#/R-SCE-69063 Loading of PCNA - Sliding Clamp Formation IEA Saccharomyces cerevisiae 61120 R-SCE-69068 https://reactome.org/PathwayBrowser/#/R-SCE-69068 RFC dissociates after sliding clamp formation IEA Saccharomyces cerevisiae 61120 R-SCE-69127 https://reactome.org/PathwayBrowser/#/R-SCE-69127 Formation of the Flap Intermediate IEA Saccharomyces cerevisiae 61120 R-SCE-69142 https://reactome.org/PathwayBrowser/#/R-SCE-69142 Recruitment of Dna2 endonuclease IEA Saccharomyces cerevisiae 61120 R-SCE-69152 https://reactome.org/PathwayBrowser/#/R-SCE-69152 Removal of remaining Flap IEA Saccharomyces cerevisiae 61120 R-SCE-69173 https://reactome.org/PathwayBrowser/#/R-SCE-69173 Joining of adjacent Okazaki fragments IEA Saccharomyces cerevisiae 61120 R-SCE-73769 https://reactome.org/PathwayBrowser/#/R-SCE-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Saccharomyces cerevisiae 61120 R-SCE-73946 https://reactome.org/PathwayBrowser/#/R-SCE-73946 Abortive initiation after formation of the first phosphodiester bond IEA Saccharomyces cerevisiae 61120 R-SCE-75095 https://reactome.org/PathwayBrowser/#/R-SCE-75095 Binding of TFIIE to the growing preinitiation complex IEA Saccharomyces cerevisiae 61120 R-SCE-75850 https://reactome.org/PathwayBrowser/#/R-SCE-75850 Addition of the third nucleotide on the nascent transcript IEA Saccharomyces cerevisiae 61120 R-SCE-75856 https://reactome.org/PathwayBrowser/#/R-SCE-75856 Abortive Initiation Before Second Transition IEA Saccharomyces cerevisiae 61120 R-SCE-75861 https://reactome.org/PathwayBrowser/#/R-SCE-75861 NTP Binds Active Site of RNA Polymerase II IEA Saccharomyces cerevisiae 61120 R-SCE-75862 https://reactome.org/PathwayBrowser/#/R-SCE-75862 Fall Back to Closed Pre-initiation Complex IEA Saccharomyces cerevisiae 61120 R-SCE-75864 https://reactome.org/PathwayBrowser/#/R-SCE-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Saccharomyces cerevisiae 61120 R-SCE-75866 https://reactome.org/PathwayBrowser/#/R-SCE-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Saccharomyces cerevisiae 61120 R-SCE-75869 https://reactome.org/PathwayBrowser/#/R-SCE-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Saccharomyces cerevisiae 61120 R-SCE-75873 https://reactome.org/PathwayBrowser/#/R-SCE-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Saccharomyces cerevisiae 61120 R-SCE-75891 https://reactome.org/PathwayBrowser/#/R-SCE-75891 Abortive Initiation After Second Transition IEA Saccharomyces cerevisiae 61120 R-SCE-75949 https://reactome.org/PathwayBrowser/#/R-SCE-75949 RNA Polymerase II Promoter Opening: First Transition IEA Saccharomyces cerevisiae 61120 R-SCE-76576 https://reactome.org/PathwayBrowser/#/R-SCE-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Saccharomyces cerevisiae 61120 R-SCE-77068 https://reactome.org/PathwayBrowser/#/R-SCE-77068 Activation of GT IEA Saccharomyces cerevisiae 61120 R-SCE-77069 https://reactome.org/PathwayBrowser/#/R-SCE-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Saccharomyces cerevisiae 61120 R-SCE-77071 https://reactome.org/PathwayBrowser/#/R-SCE-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Saccharomyces cerevisiae 61120 R-SCE-77073 https://reactome.org/PathwayBrowser/#/R-SCE-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Saccharomyces cerevisiae 61120 R-SCE-77077 https://reactome.org/PathwayBrowser/#/R-SCE-77077 Capping complex formation IEA Saccharomyces cerevisiae 61120 R-SCE-77078 https://reactome.org/PathwayBrowser/#/R-SCE-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Saccharomyces cerevisiae 61120 R-SCE-77081 https://reactome.org/PathwayBrowser/#/R-SCE-77081 Formation of the CE:GMP intermediate complex IEA Saccharomyces cerevisiae 61120 R-SCE-77083 https://reactome.org/PathwayBrowser/#/R-SCE-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Saccharomyces cerevisiae 61120 R-SCE-77085 https://reactome.org/PathwayBrowser/#/R-SCE-77085 Dissociation of transcript with 5'-GMP from GT IEA Saccharomyces cerevisiae 61120 R-SCE-77090 https://reactome.org/PathwayBrowser/#/R-SCE-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Saccharomyces cerevisiae 61120 R-SCE-83805 https://reactome.org/PathwayBrowser/#/R-SCE-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Saccharomyces cerevisiae 61120 R-SCE-9613494 https://reactome.org/PathwayBrowser/#/R-SCE-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Saccharomyces cerevisiae 61120 R-SCE-9613497 https://reactome.org/PathwayBrowser/#/R-SCE-9613497 Unwinding DNA for the nascent transcript IEA Saccharomyces cerevisiae 61120 R-SCE-9684118 https://reactome.org/PathwayBrowser/#/R-SCE-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Saccharomyces cerevisiae 61120 R-SCE-9749345 https://reactome.org/PathwayBrowser/#/R-SCE-9749345 CDT1-mediated loading of MCM2-7 to replication origin in budding yeast TAS Saccharomyces cerevisiae 61120 R-SCE-9749381 https://reactome.org/PathwayBrowser/#/R-SCE-9749381 ATP-dependent release of CDT1 from the OCCM complex in budding yeast TAS Saccharomyces cerevisiae 61120 R-SCE-9749401 https://reactome.org/PathwayBrowser/#/R-SCE-9749401 CTD1-mediated formation of MCM2-7 double hexamers at the replication origins in budding yeast TAS Saccharomyces cerevisiae 61120 R-SCE-981784 https://reactome.org/PathwayBrowser/#/R-SCE-981784 Removal of SPO11 and Resection of 5' Ends of DNA (yeast) TAS Saccharomyces cerevisiae 61120 R-SPO-109636 https://reactome.org/PathwayBrowser/#/R-SPO-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Schizosaccharomyces pombe 61120 R-SPO-109637 https://reactome.org/PathwayBrowser/#/R-SPO-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Schizosaccharomyces pombe 61120 R-SPO-109638 https://reactome.org/PathwayBrowser/#/R-SPO-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Schizosaccharomyces pombe 61120 R-SPO-109639 https://reactome.org/PathwayBrowser/#/R-SPO-109639 Formation of the closed pre-initiation complex IEA Schizosaccharomyces pombe 61120 R-SPO-111264 https://reactome.org/PathwayBrowser/#/R-SPO-111264 Addition of nucleotides between position +11 and +30 IEA Schizosaccharomyces pombe 61120 R-SPO-113430 https://reactome.org/PathwayBrowser/#/R-SPO-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Schizosaccharomyces pombe 61120 R-SPO-113504 https://reactome.org/PathwayBrowser/#/R-SPO-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Schizosaccharomyces pombe 61120 R-SPO-163296 https://reactome.org/PathwayBrowser/#/R-SPO-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Schizosaccharomyces pombe 61120 R-SPO-163310 https://reactome.org/PathwayBrowser/#/R-SPO-163310 TFAM binds to mitochondrial promoters IEA Schizosaccharomyces pombe 61120 R-SPO-174451 https://reactome.org/PathwayBrowser/#/R-SPO-174451 Recruitment of DNA2 endonuclease to the C strand IEA Schizosaccharomyces pombe 61120 R-SPO-176101 https://reactome.org/PathwayBrowser/#/R-SPO-176101 Recruitment of Rad17-RFC complex to DNA IEA Schizosaccharomyces pombe 61120 R-SPO-176175 https://reactome.org/PathwayBrowser/#/R-SPO-176175 Stalling of DNA replication fork and RPA binding IEA Schizosaccharomyces pombe 61120 R-SPO-176264 https://reactome.org/PathwayBrowser/#/R-SPO-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Schizosaccharomyces pombe 61120 R-SPO-3785768 https://reactome.org/PathwayBrowser/#/R-SPO-3785768 MRN complex binds DNA double strand breaks IEA Schizosaccharomyces pombe 61120 R-SPO-5682018 https://reactome.org/PathwayBrowser/#/R-SPO-5682018 MRN complex bound to shortened telomeres recruits ATM IEA Schizosaccharomyces pombe 61120 R-SPO-5682020 https://reactome.org/PathwayBrowser/#/R-SPO-5682020 MRN complex binds shortened telomeres IEA Schizosaccharomyces pombe 61120 R-SPO-5682026 https://reactome.org/PathwayBrowser/#/R-SPO-5682026 MRN bound to shortened telomeres activates ATM IEA Schizosaccharomyces pombe 61120 R-SPO-5682044 https://reactome.org/PathwayBrowser/#/R-SPO-5682044 KAT5 acetylates ATM at DNA DSBs IEA Schizosaccharomyces pombe 61120 R-SPO-5682588 https://reactome.org/PathwayBrowser/#/R-SPO-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Schizosaccharomyces pombe 61120 R-SPO-5682598 https://reactome.org/PathwayBrowser/#/R-SPO-5682598 ATM phosphorylates HERC2 IEA Schizosaccharomyces pombe 61120 R-SPO-5682607 https://reactome.org/PathwayBrowser/#/R-SPO-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Schizosaccharomyces pombe 61120 R-SPO-5682629 https://reactome.org/PathwayBrowser/#/R-SPO-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Schizosaccharomyces pombe 61120 R-SPO-5682858 https://reactome.org/PathwayBrowser/#/R-SPO-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Schizosaccharomyces pombe 61120 R-SPO-5682965 https://reactome.org/PathwayBrowser/#/R-SPO-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Schizosaccharomyces pombe 61120 R-SPO-5682967 https://reactome.org/PathwayBrowser/#/R-SPO-5682967 WHSC1 binds DNA DSBs IEA Schizosaccharomyces pombe 61120 R-SPO-5682983 https://reactome.org/PathwayBrowser/#/R-SPO-5682983 ATM phosphorylates WHSC1 IEA Schizosaccharomyces pombe 61120 R-SPO-5683405 https://reactome.org/PathwayBrowser/#/R-SPO-5683405 PPP5C dephosphorylates TP53BP1 IEA Schizosaccharomyces pombe 61120 R-SPO-5683425 https://reactome.org/PathwayBrowser/#/R-SPO-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Schizosaccharomyces pombe 61120 R-SPO-5684096 https://reactome.org/PathwayBrowser/#/R-SPO-5684096 CDK2 phosphorylates RBBP8 IEA Schizosaccharomyces pombe 61120 R-SPO-5684140 https://reactome.org/PathwayBrowser/#/R-SPO-5684140 ATM phosphorylates RBBP8 IEA Schizosaccharomyces pombe 61120 R-SPO-5687464 https://reactome.org/PathwayBrowser/#/R-SPO-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Schizosaccharomyces pombe 61120 R-SPO-5687664 https://reactome.org/PathwayBrowser/#/R-SPO-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Schizosaccharomyces pombe 61120 R-SPO-5689317 https://reactome.org/PathwayBrowser/#/R-SPO-5689317 Formation of the pre-incision complex in GG-NER IEA Schizosaccharomyces pombe 61120 R-SPO-5689861 https://reactome.org/PathwayBrowser/#/R-SPO-5689861 Recruitment of XPA and release of CAK IEA Schizosaccharomyces pombe 61120 R-SPO-5690213 https://reactome.org/PathwayBrowser/#/R-SPO-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Schizosaccharomyces pombe 61120 R-SPO-5690990 https://reactome.org/PathwayBrowser/#/R-SPO-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Schizosaccharomyces pombe 61120 R-SPO-5690991 https://reactome.org/PathwayBrowser/#/R-SPO-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Schizosaccharomyces pombe 61120 R-SPO-5690996 https://reactome.org/PathwayBrowser/#/R-SPO-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Schizosaccharomyces pombe 61120 R-SPO-5691001 https://reactome.org/PathwayBrowser/#/R-SPO-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Schizosaccharomyces pombe 61120 R-SPO-5693536 https://reactome.org/PathwayBrowser/#/R-SPO-5693536 ATM phosphorylates MDC1 IEA Schizosaccharomyces pombe 61120 R-SPO-5693540 https://reactome.org/PathwayBrowser/#/R-SPO-5693540 MRN activates ATM IEA Schizosaccharomyces pombe 61120 R-SPO-5693549 https://reactome.org/PathwayBrowser/#/R-SPO-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Schizosaccharomyces pombe 61120 R-SPO-5693566 https://reactome.org/PathwayBrowser/#/R-SPO-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Schizosaccharomyces pombe 61120 R-SPO-5693598 https://reactome.org/PathwayBrowser/#/R-SPO-5693598 ATM phosphorylates NBN IEA Schizosaccharomyces pombe 61120 R-SPO-5693602 https://reactome.org/PathwayBrowser/#/R-SPO-5693602 ATM recognizes H2AFX-Nucleosomes IEA Schizosaccharomyces pombe 61120 R-SPO-5693612 https://reactome.org/PathwayBrowser/#/R-SPO-5693612 MRN complex bound to DNA ends recruits ATM IEA Schizosaccharomyces pombe 61120 R-SPO-6781818 https://reactome.org/PathwayBrowser/#/R-SPO-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Schizosaccharomyces pombe 61120 R-SPO-6781824 https://reactome.org/PathwayBrowser/#/R-SPO-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Schizosaccharomyces pombe 61120 R-SPO-6781840 https://reactome.org/PathwayBrowser/#/R-SPO-6781840 ERCC6 binds stalled RNA Pol II IEA Schizosaccharomyces pombe 61120 R-SPO-6781867 https://reactome.org/PathwayBrowser/#/R-SPO-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Schizosaccharomyces pombe 61120 R-SPO-6782069 https://reactome.org/PathwayBrowser/#/R-SPO-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Schizosaccharomyces pombe 61120 R-SPO-6782131 https://reactome.org/PathwayBrowser/#/R-SPO-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Schizosaccharomyces pombe 61120 R-SPO-6782138 https://reactome.org/PathwayBrowser/#/R-SPO-6782138 ERCC5 and RPA bind TC-NER site IEA Schizosaccharomyces pombe 61120 R-SPO-6782141 https://reactome.org/PathwayBrowser/#/R-SPO-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Schizosaccharomyces pombe 61120 R-SPO-6782204 https://reactome.org/PathwayBrowser/#/R-SPO-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Schizosaccharomyces pombe 61120 R-SPO-6782208 https://reactome.org/PathwayBrowser/#/R-SPO-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Schizosaccharomyces pombe 61120 R-SPO-6782211 https://reactome.org/PathwayBrowser/#/R-SPO-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Schizosaccharomyces pombe 61120 R-SPO-6782224 https://reactome.org/PathwayBrowser/#/R-SPO-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Schizosaccharomyces pombe 61120 R-SPO-6782227 https://reactome.org/PathwayBrowser/#/R-SPO-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Schizosaccharomyces pombe 61120 R-SPO-6790454 https://reactome.org/PathwayBrowser/#/R-SPO-6790454 SUMOylation of XPC IEA Schizosaccharomyces pombe 61120 R-SPO-6792712 https://reactome.org/PathwayBrowser/#/R-SPO-6792712 KAT5 acetylates ATM at shortened telomeres IEA Schizosaccharomyces pombe 61120 R-SPO-68913 https://reactome.org/PathwayBrowser/#/R-SPO-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Schizosaccharomyces pombe 61120 R-SPO-68914 https://reactome.org/PathwayBrowser/#/R-SPO-68914 DNA polymerase alpha:primase binds at the origin IEA Schizosaccharomyces pombe 61120 R-SPO-68944 https://reactome.org/PathwayBrowser/#/R-SPO-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Schizosaccharomyces pombe 61120 R-SPO-68950 https://reactome.org/PathwayBrowser/#/R-SPO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Schizosaccharomyces pombe 61120 R-SPO-68960 https://reactome.org/PathwayBrowser/#/R-SPO-68960 DNA polymerase epsilon binds at the origin IEA Schizosaccharomyces pombe 61120 R-SPO-69053 https://reactome.org/PathwayBrowser/#/R-SPO-69053 RFC binding displaces Pol Alpha IEA Schizosaccharomyces pombe 61120 R-SPO-69063 https://reactome.org/PathwayBrowser/#/R-SPO-69063 Loading of PCNA - Sliding Clamp Formation IEA Schizosaccharomyces pombe 61120 R-SPO-69068 https://reactome.org/PathwayBrowser/#/R-SPO-69068 RFC dissociates after sliding clamp formation IEA Schizosaccharomyces pombe 61120 R-SPO-69074 https://reactome.org/PathwayBrowser/#/R-SPO-69074 Formation of Processive Complex IEA Schizosaccharomyces pombe 61120 R-SPO-69116 https://reactome.org/PathwayBrowser/#/R-SPO-69116 Formation of Okazaki fragments IEA Schizosaccharomyces pombe 61120 R-SPO-69127 https://reactome.org/PathwayBrowser/#/R-SPO-69127 Formation of the Flap Intermediate IEA Schizosaccharomyces pombe 61120 R-SPO-69140 https://reactome.org/PathwayBrowser/#/R-SPO-69140 RPA binds to the Flap IEA Schizosaccharomyces pombe 61120 R-SPO-69142 https://reactome.org/PathwayBrowser/#/R-SPO-69142 Recruitment of Dna2 endonuclease IEA Schizosaccharomyces pombe 61120 R-SPO-69144 https://reactome.org/PathwayBrowser/#/R-SPO-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Schizosaccharomyces pombe 61120 R-SPO-69152 https://reactome.org/PathwayBrowser/#/R-SPO-69152 Removal of remaining Flap IEA Schizosaccharomyces pombe 61120 R-SPO-69173 https://reactome.org/PathwayBrowser/#/R-SPO-69173 Joining of adjacent Okazaki fragments IEA Schizosaccharomyces pombe 61120 R-SPO-73769 https://reactome.org/PathwayBrowser/#/R-SPO-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Schizosaccharomyces pombe 61120 R-SPO-73946 https://reactome.org/PathwayBrowser/#/R-SPO-73946 Abortive initiation after formation of the first phosphodiester bond IEA Schizosaccharomyces pombe 61120 R-SPO-75095 https://reactome.org/PathwayBrowser/#/R-SPO-75095 Binding of TFIIE to the growing preinitiation complex IEA Schizosaccharomyces pombe 61120 R-SPO-75850 https://reactome.org/PathwayBrowser/#/R-SPO-75850 Addition of the third nucleotide on the nascent transcript IEA Schizosaccharomyces pombe 61120 R-SPO-75856 https://reactome.org/PathwayBrowser/#/R-SPO-75856 Abortive Initiation Before Second Transition IEA Schizosaccharomyces pombe 61120 R-SPO-75861 https://reactome.org/PathwayBrowser/#/R-SPO-75861 NTP Binds Active Site of RNA Polymerase II IEA Schizosaccharomyces pombe 61120 R-SPO-75862 https://reactome.org/PathwayBrowser/#/R-SPO-75862 Fall Back to Closed Pre-initiation Complex IEA Schizosaccharomyces pombe 61120 R-SPO-75864 https://reactome.org/PathwayBrowser/#/R-SPO-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Schizosaccharomyces pombe 61120 R-SPO-75866 https://reactome.org/PathwayBrowser/#/R-SPO-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Schizosaccharomyces pombe 61120 R-SPO-75869 https://reactome.org/PathwayBrowser/#/R-SPO-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Schizosaccharomyces pombe 61120 R-SPO-75873 https://reactome.org/PathwayBrowser/#/R-SPO-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Schizosaccharomyces pombe 61120 R-SPO-75891 https://reactome.org/PathwayBrowser/#/R-SPO-75891 Abortive Initiation After Second Transition IEA Schizosaccharomyces pombe 61120 R-SPO-75949 https://reactome.org/PathwayBrowser/#/R-SPO-75949 RNA Polymerase II Promoter Opening: First Transition IEA Schizosaccharomyces pombe 61120 R-SPO-76056 https://reactome.org/PathwayBrowser/#/R-SPO-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Schizosaccharomyces pombe 61120 R-SPO-76576 https://reactome.org/PathwayBrowser/#/R-SPO-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Schizosaccharomyces pombe 61120 R-SPO-77068 https://reactome.org/PathwayBrowser/#/R-SPO-77068 Activation of GT IEA Schizosaccharomyces pombe 61120 R-SPO-77069 https://reactome.org/PathwayBrowser/#/R-SPO-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Schizosaccharomyces pombe 61120 R-SPO-77071 https://reactome.org/PathwayBrowser/#/R-SPO-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Schizosaccharomyces pombe 61120 R-SPO-77073 https://reactome.org/PathwayBrowser/#/R-SPO-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Schizosaccharomyces pombe 61120 R-SPO-77077 https://reactome.org/PathwayBrowser/#/R-SPO-77077 Capping complex formation IEA Schizosaccharomyces pombe 61120 R-SPO-77078 https://reactome.org/PathwayBrowser/#/R-SPO-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Schizosaccharomyces pombe 61120 R-SPO-77081 https://reactome.org/PathwayBrowser/#/R-SPO-77081 Formation of the CE:GMP intermediate complex IEA Schizosaccharomyces pombe 61120 R-SPO-77083 https://reactome.org/PathwayBrowser/#/R-SPO-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Schizosaccharomyces pombe 61120 R-SPO-77085 https://reactome.org/PathwayBrowser/#/R-SPO-77085 Dissociation of transcript with 5'-GMP from GT IEA Schizosaccharomyces pombe 61120 R-SPO-77090 https://reactome.org/PathwayBrowser/#/R-SPO-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Schizosaccharomyces pombe 61120 R-SPO-83723 https://reactome.org/PathwayBrowser/#/R-SPO-83723 Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex IEA Schizosaccharomyces pombe 61120 R-SPO-83788 https://reactome.org/PathwayBrowser/#/R-SPO-83788 Binding of TFIIIC to Type 2 promoter IEA Schizosaccharomyces pombe 61120 R-SPO-83790 https://reactome.org/PathwayBrowser/#/R-SPO-83790 Binding of TFIIIB to TFIIC: Type 2 Promoter Complex IEA Schizosaccharomyces pombe 61120 R-SPO-83805 https://reactome.org/PathwayBrowser/#/R-SPO-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Schizosaccharomyces pombe 61120 R-SPO-9613494 https://reactome.org/PathwayBrowser/#/R-SPO-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Schizosaccharomyces pombe 61120 R-SPO-9613497 https://reactome.org/PathwayBrowser/#/R-SPO-9613497 Unwinding DNA for the nascent transcript IEA Schizosaccharomyces pombe 61120 R-SPO-9684118 https://reactome.org/PathwayBrowser/#/R-SPO-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Schizosaccharomyces pombe 61120 R-SSC-1008200 https://reactome.org/PathwayBrowser/#/R-SSC-1008200 NFE2 binds the beta globin locus control region IEA Sus scrofa 61120 R-SSC-109636 https://reactome.org/PathwayBrowser/#/R-SSC-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Sus scrofa 61120 R-SSC-109637 https://reactome.org/PathwayBrowser/#/R-SSC-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Sus scrofa 61120 R-SSC-109638 https://reactome.org/PathwayBrowser/#/R-SSC-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Sus scrofa 61120 R-SSC-109639 https://reactome.org/PathwayBrowser/#/R-SSC-109639 Formation of the closed pre-initiation complex IEA Sus scrofa 61120 R-SSC-109699 https://reactome.org/PathwayBrowser/#/R-SSC-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Sus scrofa 61120 R-SSC-111264 https://reactome.org/PathwayBrowser/#/R-SSC-111264 Addition of nucleotides between position +11 and +30 IEA Sus scrofa 61120 R-SSC-112379 https://reactome.org/PathwayBrowser/#/R-SSC-112379 Recruitment of elongation factors to form elongation complex IEA Sus scrofa 61120 R-SSC-112381 https://reactome.org/PathwayBrowser/#/R-SSC-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Sus scrofa 61120 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa 61120 R-SSC-113429 https://reactome.org/PathwayBrowser/#/R-SSC-113429 Elongating transcript encounters a lesion in the template IEA Sus scrofa 61120 R-SSC-113430 https://reactome.org/PathwayBrowser/#/R-SSC-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Sus scrofa 61120 R-SSC-113503 https://reactome.org/PathwayBrowser/#/R-SSC-113503 PP2A mediated localization of RB1 protein in chromatin IEA Sus scrofa 61120 R-SSC-113504 https://reactome.org/PathwayBrowser/#/R-SSC-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Sus scrofa 61120 R-SSC-1535903 https://reactome.org/PathwayBrowser/#/R-SSC-1535903 Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements IEA Sus scrofa 61120 R-SSC-163296 https://reactome.org/PathwayBrowser/#/R-SSC-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Sus scrofa 61120 R-SSC-163310 https://reactome.org/PathwayBrowser/#/R-SSC-163310 TFAM binds to mitochondrial promoters IEA Sus scrofa 61120 R-SSC-163320 https://reactome.org/PathwayBrowser/#/R-SSC-163320 Association of mTERF with the termination sequence IEA Sus scrofa 61120 R-SSC-1679098 https://reactome.org/PathwayBrowser/#/R-SSC-1679098 Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer IEA Sus scrofa 61120 R-SSC-1679589 https://reactome.org/PathwayBrowser/#/R-SSC-1679589 Engulfed CpG DNA binds to endosomal full-length TLR9 IEA Sus scrofa 61120 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa 61120 R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa 61120 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa 61120 R-SSC-174441 https://reactome.org/PathwayBrowser/#/R-SSC-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Sus scrofa 61120 R-SSC-174444 https://reactome.org/PathwayBrowser/#/R-SSC-174444 Formation of C-strand Okazaki fragments IEA Sus scrofa 61120 R-SSC-174445 https://reactome.org/PathwayBrowser/#/R-SSC-174445 RPA binds to the Flap on the C-strand IEA Sus scrofa 61120 R-SSC-174446 https://reactome.org/PathwayBrowser/#/R-SSC-174446 Removal of remaining Flap from the C-strand IEA Sus scrofa 61120 R-SSC-174447 https://reactome.org/PathwayBrowser/#/R-SSC-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Sus scrofa 61120 R-SSC-174448 https://reactome.org/PathwayBrowser/#/R-SSC-174448 Formation of Processive Complex on the C-strand of the telomere IEA Sus scrofa 61120 R-SSC-174451 https://reactome.org/PathwayBrowser/#/R-SSC-174451 Recruitment of DNA2 endonuclease to the C strand IEA Sus scrofa 61120 R-SSC-174452 https://reactome.org/PathwayBrowser/#/R-SSC-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Sus scrofa 61120 R-SSC-174456 https://reactome.org/PathwayBrowser/#/R-SSC-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Sus scrofa 61120 R-SSC-176101 https://reactome.org/PathwayBrowser/#/R-SSC-176101 Recruitment of Rad17-RFC complex to DNA IEA Sus scrofa 61120 R-SSC-176175 https://reactome.org/PathwayBrowser/#/R-SSC-176175 Stalling of DNA replication fork and RPA binding IEA Sus scrofa 61120 R-SSC-176250 https://reactome.org/PathwayBrowser/#/R-SSC-176250 Binding of ATR-ATRIP to the RPA-ssDNA complex IEA Sus scrofa 61120 R-SSC-176264 https://reactome.org/PathwayBrowser/#/R-SSC-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Sus scrofa 61120 R-SSC-187895 https://reactome.org/PathwayBrowser/#/R-SSC-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 IEA Sus scrofa 61120 R-SSC-188002 https://reactome.org/PathwayBrowser/#/R-SSC-188002 Rab5-mediated recruitment of class III PI3K to TLR9 IEA Sus scrofa 61120 R-SSC-211247 https://reactome.org/PathwayBrowser/#/R-SSC-211247 Cleavage of DNA by DFF40 IEA Sus scrofa 61120 R-SSC-3134883 https://reactome.org/PathwayBrowser/#/R-SSC-3134883 Beta-catenin enhances association of IRF3 with CBP/p300 IEA Sus scrofa 61120 R-SSC-3134953 https://reactome.org/PathwayBrowser/#/R-SSC-3134953 DHX36 or DHX9 binds MyD88 IEA Sus scrofa 61120 R-SSC-3134954 https://reactome.org/PathwayBrowser/#/R-SSC-3134954 DHX9 binds DNA IEA Sus scrofa 61120 R-SSC-3134962 https://reactome.org/PathwayBrowser/#/R-SSC-3134962 DHX36 binds DNA IEA Sus scrofa 61120 R-SSC-3785711 https://reactome.org/PathwayBrowser/#/R-SSC-3785711 Telomere shortening during replicative exhaustion IEA Sus scrofa 61120 R-SSC-3785768 https://reactome.org/PathwayBrowser/#/R-SSC-3785768 MRN complex binds DNA double strand breaks IEA Sus scrofa 61120 R-SSC-400183 https://reactome.org/PathwayBrowser/#/R-SSC-400183 PPARA:RXRA binds Corepressors of PPARA IEA Sus scrofa 61120 R-SSC-400204 https://reactome.org/PathwayBrowser/#/R-SSC-400204 PPARA binds RXRA IEA Sus scrofa 61120 R-SSC-5250930 https://reactome.org/PathwayBrowser/#/R-SSC-5250930 B-WICH recruits histone acetyltransferases IEA Sus scrofa 61120 R-SSC-5250938 https://reactome.org/PathwayBrowser/#/R-SSC-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Sus scrofa 61120 R-SSC-5682018 https://reactome.org/PathwayBrowser/#/R-SSC-5682018 MRN complex bound to shortened telomeres recruits ATM IEA Sus scrofa 61120 R-SSC-5682020 https://reactome.org/PathwayBrowser/#/R-SSC-5682020 MRN complex binds shortened telomeres IEA Sus scrofa 61120 R-SSC-5682026 https://reactome.org/PathwayBrowser/#/R-SSC-5682026 MRN bound to shortened telomeres activates ATM IEA Sus scrofa 61120 R-SSC-5682044 https://reactome.org/PathwayBrowser/#/R-SSC-5682044 KAT5 acetylates ATM at DNA DSBs IEA Sus scrofa 61120 R-SSC-5682586 https://reactome.org/PathwayBrowser/#/R-SSC-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Sus scrofa 61120 R-SSC-5682588 https://reactome.org/PathwayBrowser/#/R-SSC-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Sus scrofa 61120 R-SSC-5682598 https://reactome.org/PathwayBrowser/#/R-SSC-5682598 ATM phosphorylates HERC2 IEA Sus scrofa 61120 R-SSC-5682607 https://reactome.org/PathwayBrowser/#/R-SSC-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Sus scrofa 61120 R-SSC-5682858 https://reactome.org/PathwayBrowser/#/R-SSC-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Sus scrofa 61120 R-SSC-5682863 https://reactome.org/PathwayBrowser/#/R-SSC-5682863 RNF168 binds DNA DSBs IEA Sus scrofa 61120 R-SSC-5682965 https://reactome.org/PathwayBrowser/#/R-SSC-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Sus scrofa 61120 R-SSC-5682967 https://reactome.org/PathwayBrowser/#/R-SSC-5682967 WHSC1 binds DNA DSBs IEA Sus scrofa 61120 R-SSC-5682983 https://reactome.org/PathwayBrowser/#/R-SSC-5682983 ATM phosphorylates WHSC1 IEA Sus scrofa 61120 R-SSC-5682992 https://reactome.org/PathwayBrowser/#/R-SSC-5682992 KDM4A,B bind H4K20Me2 IEA Sus scrofa 61120 R-SSC-5683077 https://reactome.org/PathwayBrowser/#/R-SSC-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Sus scrofa 61120 R-SSC-5683384 https://reactome.org/PathwayBrowser/#/R-SSC-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Sus scrofa 61120 R-SSC-5683385 https://reactome.org/PathwayBrowser/#/R-SSC-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Sus scrofa 61120 R-SSC-5683405 https://reactome.org/PathwayBrowser/#/R-SSC-5683405 PPP5C dephosphorylates TP53BP1 IEA Sus scrofa 61120 R-SSC-5683425 https://reactome.org/PathwayBrowser/#/R-SSC-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Sus scrofa 61120 R-SSC-5683735 https://reactome.org/PathwayBrowser/#/R-SSC-5683735 CHEK2 is recruited to DNA DSBs IEA Sus scrofa 61120 R-SSC-5683801 https://reactome.org/PathwayBrowser/#/R-SSC-5683801 CHEK2 phosphorylates BRCA1 IEA Sus scrofa 61120 R-SSC-5683964 https://reactome.org/PathwayBrowser/#/R-SSC-5683964 ATM phosphorylates EYA1-4 IEA Sus scrofa 61120 R-SSC-5683967 https://reactome.org/PathwayBrowser/#/R-SSC-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Sus scrofa 61120 R-SSC-5683986 https://reactome.org/PathwayBrowser/#/R-SSC-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA Sus scrofa 61120 R-SSC-5684052 https://reactome.org/PathwayBrowser/#/R-SSC-5684052 PIAS4 SUMOylates MDC1 IEA Sus scrofa 61120 R-SSC-5684081 https://reactome.org/PathwayBrowser/#/R-SSC-5684081 MRN complex binds CDK2 and RBBP8 IEA Sus scrofa 61120 R-SSC-5684096 https://reactome.org/PathwayBrowser/#/R-SSC-5684096 CDK2 phosphorylates RBBP8 IEA Sus scrofa 61120 R-SSC-5684108 https://reactome.org/PathwayBrowser/#/R-SSC-5684108 BRCA1 binds phosphorylated RBBP8 IEA Sus scrofa 61120 R-SSC-5684140 https://reactome.org/PathwayBrowser/#/R-SSC-5684140 ATM phosphorylates RBBP8 IEA Sus scrofa 61120 R-SSC-5684875 https://reactome.org/PathwayBrowser/#/R-SSC-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Sus scrofa 61120 R-SSC-5684882 https://reactome.org/PathwayBrowser/#/R-SSC-5684882 CHEK1 is recruited to resected DNA DSBs IEA Sus scrofa 61120 R-SSC-5684887 https://reactome.org/PathwayBrowser/#/R-SSC-5684887 Activation of CHEK1 at resected DNA DSBs IEA Sus scrofa 61120 R-SSC-5685011 https://reactome.org/PathwayBrowser/#/R-SSC-5685011 ATR activation at DNA DSBs IEA Sus scrofa 61120 R-SSC-5685156 https://reactome.org/PathwayBrowser/#/R-SSC-5685156 ATR phosphorylates RPA2 IEA Sus scrofa 61120 R-SSC-5685341 https://reactome.org/PathwayBrowser/#/R-SSC-5685341 BCDX2 complex stabilizes RAD51 filament IEA Sus scrofa 61120 R-SSC-5685838 https://reactome.org/PathwayBrowser/#/R-SSC-5685838 CX3 complex binds D-loop structures IEA Sus scrofa 61120 R-SSC-5685985 https://reactome.org/PathwayBrowser/#/R-SSC-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Sus scrofa 61120 R-SSC-5685994 https://reactome.org/PathwayBrowser/#/R-SSC-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Sus scrofa 61120 R-SSC-5686440 https://reactome.org/PathwayBrowser/#/R-SSC-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Sus scrofa 61120 R-SSC-5686642 https://reactome.org/PathwayBrowser/#/R-SSC-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Sus scrofa 61120 R-SSC-5686657 https://reactome.org/PathwayBrowser/#/R-SSC-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Sus scrofa 61120 R-SSC-5686685 https://reactome.org/PathwayBrowser/#/R-SSC-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Sus scrofa 61120 R-SSC-5686704 https://reactome.org/PathwayBrowser/#/R-SSC-5686704 Activated ATM phosphorylates DCLRE1C IEA Sus scrofa 61120 R-SSC-5686900 https://reactome.org/PathwayBrowser/#/R-SSC-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Sus scrofa 61120 R-SSC-5686924 https://reactome.org/PathwayBrowser/#/R-SSC-5686924 DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs IEA Sus scrofa 61120 R-SSC-5687183 https://reactome.org/PathwayBrowser/#/R-SSC-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Sus scrofa 61120 R-SSC-5687360 https://reactome.org/PathwayBrowser/#/R-SSC-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Sus scrofa 61120 R-SSC-5687464 https://reactome.org/PathwayBrowser/#/R-SSC-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Sus scrofa 61120 R-SSC-5687465 https://reactome.org/PathwayBrowser/#/R-SSC-5687465 MRN complex binds RBBP8 IEA Sus scrofa 61120 R-SSC-5687484 https://reactome.org/PathwayBrowser/#/R-SSC-5687484 PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site IEA Sus scrofa 61120 R-SSC-5687640 https://reactome.org/PathwayBrowser/#/R-SSC-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Sus scrofa 61120 R-SSC-5687653 https://reactome.org/PathwayBrowser/#/R-SSC-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Sus scrofa 61120 R-SSC-5687664 https://reactome.org/PathwayBrowser/#/R-SSC-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Sus scrofa 61120 R-SSC-5687673 https://reactome.org/PathwayBrowser/#/R-SSC-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites IEA Sus scrofa 61120 R-SSC-5687675 https://reactome.org/PathwayBrowser/#/R-SSC-5687675 LIG3 ligates remaining SSBs in MMEJ IEA Sus scrofa 61120 R-SSC-5689317 https://reactome.org/PathwayBrowser/#/R-SSC-5689317 Formation of the pre-incision complex in GG-NER IEA Sus scrofa 61120 R-SSC-5689861 https://reactome.org/PathwayBrowser/#/R-SSC-5689861 Recruitment of XPA and release of CAK IEA Sus scrofa 61120 R-SSC-5690213 https://reactome.org/PathwayBrowser/#/R-SSC-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Sus scrofa 61120 R-SSC-5690988 https://reactome.org/PathwayBrowser/#/R-SSC-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Sus scrofa 61120 R-SSC-5690990 https://reactome.org/PathwayBrowser/#/R-SSC-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Sus scrofa 61120 R-SSC-5690991 https://reactome.org/PathwayBrowser/#/R-SSC-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Sus scrofa 61120 R-SSC-5690996 https://reactome.org/PathwayBrowser/#/R-SSC-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Sus scrofa 61120 R-SSC-5691000 https://reactome.org/PathwayBrowser/#/R-SSC-5691000 TFIIH binds GG-NER site to form a verification complex IEA Sus scrofa 61120 R-SSC-5691001 https://reactome.org/PathwayBrowser/#/R-SSC-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Sus scrofa 61120 R-SSC-5693533 https://reactome.org/PathwayBrowser/#/R-SSC-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends IEA Sus scrofa 61120 R-SSC-5693536 https://reactome.org/PathwayBrowser/#/R-SSC-5693536 ATM phosphorylates MDC1 IEA Sus scrofa 61120 R-SSC-5693539 https://reactome.org/PathwayBrowser/#/R-SSC-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Sus scrofa 61120 R-SSC-5693540 https://reactome.org/PathwayBrowser/#/R-SSC-5693540 MRN activates ATM IEA Sus scrofa 61120 R-SSC-5693542 https://reactome.org/PathwayBrowser/#/R-SSC-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Sus scrofa 61120 R-SSC-5693549 https://reactome.org/PathwayBrowser/#/R-SSC-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Sus scrofa 61120 R-SSC-5693551 https://reactome.org/PathwayBrowser/#/R-SSC-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Sus scrofa 61120 R-SSC-5693564 https://reactome.org/PathwayBrowser/#/R-SSC-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Sus scrofa 61120 R-SSC-5693566 https://reactome.org/PathwayBrowser/#/R-SSC-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Sus scrofa 61120 R-SSC-5693575 https://reactome.org/PathwayBrowser/#/R-SSC-5693575 DNA-PKcs autophosphorylates IEA Sus scrofa 61120 R-SSC-5693578 https://reactome.org/PathwayBrowser/#/R-SSC-5693578 TDP1 and TDP2 process unligatable DSB ends IEA Sus scrofa 61120 R-SSC-5693580 https://reactome.org/PathwayBrowser/#/R-SSC-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Sus scrofa 61120 R-SSC-5693583 https://reactome.org/PathwayBrowser/#/R-SSC-5693583 MDC1 associates with gamma-H2AFX at nuclear foci IEA Sus scrofa 61120 R-SSC-5693584 https://reactome.org/PathwayBrowser/#/R-SSC-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Sus scrofa 61120 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa 61120 R-SSC-5693598 https://reactome.org/PathwayBrowser/#/R-SSC-5693598 ATM phosphorylates NBN IEA Sus scrofa 61120 R-SSC-5693608 https://reactome.org/PathwayBrowser/#/R-SSC-5693608 Initial resection of double-strand break ends IEA Sus scrofa 61120 R-SSC-5693612 https://reactome.org/PathwayBrowser/#/R-SSC-5693612 MRN complex bound to DNA ends recruits ATM IEA Sus scrofa 61120 R-SSC-5693615 https://reactome.org/PathwayBrowser/#/R-SSC-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis IEA Sus scrofa 61120 R-SSC-5693620 https://reactome.org/PathwayBrowser/#/R-SSC-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Sus scrofa 61120 R-SSC-5696655 https://reactome.org/PathwayBrowser/#/R-SSC-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Sus scrofa 61120 R-SSC-5696664 https://reactome.org/PathwayBrowser/#/R-SSC-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Sus scrofa 61120 R-SSC-5696670 https://reactome.org/PathwayBrowser/#/R-SSC-5696670 CHD1L is recruited to GG-NER site IEA Sus scrofa 61120 R-SSC-6781818 https://reactome.org/PathwayBrowser/#/R-SSC-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Sus scrofa 61120 R-SSC-6781824 https://reactome.org/PathwayBrowser/#/R-SSC-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Sus scrofa 61120 R-SSC-6781833 https://reactome.org/PathwayBrowser/#/R-SSC-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Sus scrofa 61120 R-SSC-6781867 https://reactome.org/PathwayBrowser/#/R-SSC-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Sus scrofa 61120 R-SSC-6782004 https://reactome.org/PathwayBrowser/#/R-SSC-6782004 Assembly of the pre-incision complex in TC-NER IEA Sus scrofa 61120 R-SSC-6782069 https://reactome.org/PathwayBrowser/#/R-SSC-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Sus scrofa 61120 R-SSC-6782131 https://reactome.org/PathwayBrowser/#/R-SSC-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa 61120 R-SSC-6782138 https://reactome.org/PathwayBrowser/#/R-SSC-6782138 ERCC5 and RPA bind TC-NER site IEA Sus scrofa 61120 R-SSC-6782141 https://reactome.org/PathwayBrowser/#/R-SSC-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Sus scrofa 61120 R-SSC-6782204 https://reactome.org/PathwayBrowser/#/R-SSC-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Sus scrofa 61120 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa 61120 R-SSC-6782211 https://reactome.org/PathwayBrowser/#/R-SSC-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Sus scrofa 61120 R-SSC-6782224 https://reactome.org/PathwayBrowser/#/R-SSC-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Sus scrofa 61120 R-SSC-6782227 https://reactome.org/PathwayBrowser/#/R-SSC-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Sus scrofa 61120 R-SSC-6782943 https://reactome.org/PathwayBrowser/#/R-SSC-6782943 UV-DDB ubiquitinates XPC IEA Sus scrofa 61120 R-SSC-6786166 https://reactome.org/PathwayBrowser/#/R-SSC-6786166 Translesion synthesis across unhooked ICL by POLN IEA Sus scrofa 61120 R-SSC-6790454 https://reactome.org/PathwayBrowser/#/R-SSC-6790454 SUMOylation of XPC IEA Sus scrofa 61120 R-SSC-6792712 https://reactome.org/PathwayBrowser/#/R-SSC-6792712 KAT5 acetylates ATM at shortened telomeres IEA Sus scrofa 61120 R-SSC-6799332 https://reactome.org/PathwayBrowser/#/R-SSC-6799332 ATR phosphorylates TP53 IEA Sus scrofa 61120 R-SSC-68913 https://reactome.org/PathwayBrowser/#/R-SSC-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Sus scrofa 61120 R-SSC-68914 https://reactome.org/PathwayBrowser/#/R-SSC-68914 DNA polymerase alpha:primase binds at the origin IEA Sus scrofa 61120 R-SSC-68944 https://reactome.org/PathwayBrowser/#/R-SSC-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Sus scrofa 61120 R-SSC-68950 https://reactome.org/PathwayBrowser/#/R-SSC-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Sus scrofa 61120 R-SSC-68960 https://reactome.org/PathwayBrowser/#/R-SSC-68960 DNA polymerase epsilon binds at the origin IEA Sus scrofa 61120 R-SSC-69053 https://reactome.org/PathwayBrowser/#/R-SSC-69053 RFC binding displaces Pol Alpha IEA Sus scrofa 61120 R-SSC-69063 https://reactome.org/PathwayBrowser/#/R-SSC-69063 Loading of PCNA - Sliding Clamp Formation IEA Sus scrofa 61120 R-SSC-69068 https://reactome.org/PathwayBrowser/#/R-SSC-69068 RFC dissociates after sliding clamp formation IEA Sus scrofa 61120 R-SSC-69074 https://reactome.org/PathwayBrowser/#/R-SSC-69074 Formation of Processive Complex IEA Sus scrofa 61120 R-SSC-69116 https://reactome.org/PathwayBrowser/#/R-SSC-69116 Formation of Okazaki fragments IEA Sus scrofa 61120 R-SSC-69127 https://reactome.org/PathwayBrowser/#/R-SSC-69127 Formation of the Flap Intermediate IEA Sus scrofa 61120 R-SSC-69140 https://reactome.org/PathwayBrowser/#/R-SSC-69140 RPA binds to the Flap IEA Sus scrofa 61120 R-SSC-69142 https://reactome.org/PathwayBrowser/#/R-SSC-69142 Recruitment of Dna2 endonuclease IEA Sus scrofa 61120 R-SSC-69144 https://reactome.org/PathwayBrowser/#/R-SSC-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Sus scrofa 61120 R-SSC-69152 https://reactome.org/PathwayBrowser/#/R-SSC-69152 Removal of remaining Flap IEA Sus scrofa 61120 R-SSC-69173 https://reactome.org/PathwayBrowser/#/R-SSC-69173 Joining of adjacent Okazaki fragments IEA Sus scrofa 61120 R-SSC-69891 https://reactome.org/PathwayBrowser/#/R-SSC-69891 Phosphorylation and activation of CHEK2 by ATM IEA Sus scrofa 61120 R-SSC-73718 https://reactome.org/PathwayBrowser/#/R-SSC-73718 UBF-1 Binds rDNA Promoter IEA Sus scrofa 61120 R-SSC-73722 https://reactome.org/PathwayBrowser/#/R-SSC-73722 Phosphorylation of UBF-1:rDNA Promoter IEA Sus scrofa 61120 R-SSC-73739 https://reactome.org/PathwayBrowser/#/R-SSC-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Sus scrofa 61120 R-SSC-73758 https://reactome.org/PathwayBrowser/#/R-SSC-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Sus scrofa 61120 R-SSC-73769 https://reactome.org/PathwayBrowser/#/R-SSC-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Sus scrofa 61120 R-SSC-73946 https://reactome.org/PathwayBrowser/#/R-SSC-73946 Abortive initiation after formation of the first phosphodiester bond IEA Sus scrofa 61120 R-SSC-75095 https://reactome.org/PathwayBrowser/#/R-SSC-75095 Binding of TFIIE to the growing preinitiation complex IEA Sus scrofa 61120 R-SSC-75850 https://reactome.org/PathwayBrowser/#/R-SSC-75850 Addition of the third nucleotide on the nascent transcript IEA Sus scrofa 61120 R-SSC-75856 https://reactome.org/PathwayBrowser/#/R-SSC-75856 Abortive Initiation Before Second Transition IEA Sus scrofa 61120 R-SSC-75861 https://reactome.org/PathwayBrowser/#/R-SSC-75861 NTP Binds Active Site of RNA Polymerase II IEA Sus scrofa 61120 R-SSC-75862 https://reactome.org/PathwayBrowser/#/R-SSC-75862 Fall Back to Closed Pre-initiation Complex IEA Sus scrofa 61120 R-SSC-75864 https://reactome.org/PathwayBrowser/#/R-SSC-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Sus scrofa 61120 R-SSC-75866 https://reactome.org/PathwayBrowser/#/R-SSC-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Sus scrofa 61120 R-SSC-75869 https://reactome.org/PathwayBrowser/#/R-SSC-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Sus scrofa 61120 R-SSC-75873 https://reactome.org/PathwayBrowser/#/R-SSC-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Sus scrofa 61120 R-SSC-75891 https://reactome.org/PathwayBrowser/#/R-SSC-75891 Abortive Initiation After Second Transition IEA Sus scrofa 61120 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa 61120 R-SSC-76056 https://reactome.org/PathwayBrowser/#/R-SSC-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Sus scrofa 61120 R-SSC-76576 https://reactome.org/PathwayBrowser/#/R-SSC-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Sus scrofa 61120 R-SSC-77068 https://reactome.org/PathwayBrowser/#/R-SSC-77068 Activation of GT IEA Sus scrofa 61120 R-SSC-77069 https://reactome.org/PathwayBrowser/#/R-SSC-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Sus scrofa 61120 R-SSC-77071 https://reactome.org/PathwayBrowser/#/R-SSC-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Sus scrofa 61120 R-SSC-77073 https://reactome.org/PathwayBrowser/#/R-SSC-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Sus scrofa 61120 R-SSC-77077 https://reactome.org/PathwayBrowser/#/R-SSC-77077 Capping complex formation IEA Sus scrofa 61120 R-SSC-77078 https://reactome.org/PathwayBrowser/#/R-SSC-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Sus scrofa 61120 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa 61120 R-SSC-77083 https://reactome.org/PathwayBrowser/#/R-SSC-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Sus scrofa 61120 R-SSC-77085 https://reactome.org/PathwayBrowser/#/R-SSC-77085 Dissociation of transcript with 5'-GMP from GT IEA Sus scrofa 61120 R-SSC-77090 https://reactome.org/PathwayBrowser/#/R-SSC-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Sus scrofa 61120 R-SSC-83788 https://reactome.org/PathwayBrowser/#/R-SSC-83788 Binding of TFIIIC to Type 2 promoter IEA Sus scrofa 61120 R-SSC-83803 https://reactome.org/PathwayBrowser/#/R-SSC-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Sus scrofa 61120 R-SSC-83805 https://reactome.org/PathwayBrowser/#/R-SSC-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Sus scrofa 61120 R-SSC-9604480 https://reactome.org/PathwayBrowser/#/R-SSC-9604480 NFkB complex translocates from the cytosol to the nucleus IEA Sus scrofa 61120 R-SSC-9604487 https://reactome.org/PathwayBrowser/#/R-SSC-9604487 p-IRF7:p-IRF7 translocates to the nucleus IEA Sus scrofa 61120 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa 61120 R-SSC-9613497 https://reactome.org/PathwayBrowser/#/R-SSC-9613497 Unwinding DNA for the nascent transcript IEA Sus scrofa 61120 R-SSC-9684118 https://reactome.org/PathwayBrowser/#/R-SSC-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa 61120 R-SSC-9734475 https://reactome.org/PathwayBrowser/#/R-SSC-9734475 PPARA binds fibrates IEA Sus scrofa 61120 R-SSC-996727 https://reactome.org/PathwayBrowser/#/R-SSC-996727 REST recruits the BHC complex IEA Sus scrofa 61120 R-XLA-169440 https://reactome.org/PathwayBrowser/#/R-XLA-169440 Xenopus Mcm8 mediated fork unwinding TAS Xenopus laevis 61120 R-XLA-176971 https://reactome.org/PathwayBrowser/#/R-XLA-176971 Multiple Xenopus proteins are localized at replication fork TAS Xenopus laevis 61120 R-XLA-9636011 https://reactome.org/PathwayBrowser/#/R-XLA-9636011 neil3 resolves AP-ICLs TAS Xenopus laevis 61120 R-XTR-1008200 https://reactome.org/PathwayBrowser/#/R-XTR-1008200 NFE2 binds the beta globin locus control region IEA Xenopus tropicalis 61120 R-XTR-109636 https://reactome.org/PathwayBrowser/#/R-XTR-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Xenopus tropicalis 61120 R-XTR-109639 https://reactome.org/PathwayBrowser/#/R-XTR-109639 Formation of the closed pre-initiation complex IEA Xenopus tropicalis 61120 R-XTR-111264 https://reactome.org/PathwayBrowser/#/R-XTR-111264 Addition of nucleotides between position +11 and +30 IEA Xenopus tropicalis 61120 R-XTR-112379 https://reactome.org/PathwayBrowser/#/R-XTR-112379 Recruitment of elongation factors to form elongation complex IEA Xenopus tropicalis 61120 R-XTR-112381 https://reactome.org/PathwayBrowser/#/R-XTR-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Xenopus tropicalis 61120 R-XTR-112385 https://reactome.org/PathwayBrowser/#/R-XTR-112385 Addition of nucleotides leads to transcript elongation IEA Xenopus tropicalis 61120 R-XTR-113430 https://reactome.org/PathwayBrowser/#/R-XTR-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Xenopus tropicalis 61120 R-XTR-163296 https://reactome.org/PathwayBrowser/#/R-XTR-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Xenopus tropicalis 61120 R-XTR-163310 https://reactome.org/PathwayBrowser/#/R-XTR-163310 TFAM binds to mitochondrial promoters IEA Xenopus tropicalis 61120 R-XTR-174439 https://reactome.org/PathwayBrowser/#/R-XTR-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Xenopus tropicalis 61120 R-XTR-174447 https://reactome.org/PathwayBrowser/#/R-XTR-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Xenopus tropicalis 61120 R-XTR-176101 https://reactome.org/PathwayBrowser/#/R-XTR-176101 Recruitment of Rad17-RFC complex to DNA IEA Xenopus tropicalis 61120 R-XTR-176175 https://reactome.org/PathwayBrowser/#/R-XTR-176175 Stalling of DNA replication fork and RPA binding IEA Xenopus tropicalis 61120 R-XTR-176264 https://reactome.org/PathwayBrowser/#/R-XTR-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Xenopus tropicalis 61120 R-XTR-3134953 https://reactome.org/PathwayBrowser/#/R-XTR-3134953 DHX36 or DHX9 binds MyD88 IEA Xenopus tropicalis 61120 R-XTR-3134954 https://reactome.org/PathwayBrowser/#/R-XTR-3134954 DHX9 binds DNA IEA Xenopus tropicalis 61120 R-XTR-3134962 https://reactome.org/PathwayBrowser/#/R-XTR-3134962 DHX36 binds DNA IEA Xenopus tropicalis 61120 R-XTR-3785711 https://reactome.org/PathwayBrowser/#/R-XTR-3785711 Telomere shortening during replicative exhaustion IEA Xenopus tropicalis 61120 R-XTR-400183 https://reactome.org/PathwayBrowser/#/R-XTR-400183 PPARA:RXRA binds Corepressors of PPARA IEA Xenopus tropicalis 61120 R-XTR-400204 https://reactome.org/PathwayBrowser/#/R-XTR-400204 PPARA binds RXRA IEA Xenopus tropicalis 61120 R-XTR-5685156 https://reactome.org/PathwayBrowser/#/R-XTR-5685156 ATR phosphorylates RPA2 IEA Xenopus tropicalis 61120 R-XTR-5686642 https://reactome.org/PathwayBrowser/#/R-XTR-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Xenopus tropicalis 61120 R-XTR-5687360 https://reactome.org/PathwayBrowser/#/R-XTR-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Xenopus tropicalis 61120 R-XTR-5689861 https://reactome.org/PathwayBrowser/#/R-XTR-5689861 Recruitment of XPA and release of CAK IEA Xenopus tropicalis 61120 R-XTR-5690990 https://reactome.org/PathwayBrowser/#/R-XTR-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Xenopus tropicalis 61120 R-XTR-5690996 https://reactome.org/PathwayBrowser/#/R-XTR-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Xenopus tropicalis 61120 R-XTR-5691000 https://reactome.org/PathwayBrowser/#/R-XTR-5691000 TFIIH binds GG-NER site to form a verification complex IEA Xenopus tropicalis 61120 R-XTR-5691001 https://reactome.org/PathwayBrowser/#/R-XTR-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Xenopus tropicalis 61120 R-XTR-5691006 https://reactome.org/PathwayBrowser/#/R-XTR-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Xenopus tropicalis 61120 R-XTR-5693564 https://reactome.org/PathwayBrowser/#/R-XTR-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Xenopus tropicalis 61120 R-XTR-5693580 https://reactome.org/PathwayBrowser/#/R-XTR-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Xenopus tropicalis 61120 R-XTR-5696655 https://reactome.org/PathwayBrowser/#/R-XTR-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Xenopus tropicalis 61120 R-XTR-5696664 https://reactome.org/PathwayBrowser/#/R-XTR-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Xenopus tropicalis 61120 R-XTR-6781818 https://reactome.org/PathwayBrowser/#/R-XTR-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Xenopus tropicalis 61120 R-XTR-6781824 https://reactome.org/PathwayBrowser/#/R-XTR-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Xenopus tropicalis 61120 R-XTR-6781833 https://reactome.org/PathwayBrowser/#/R-XTR-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Xenopus tropicalis 61120 R-XTR-6781840 https://reactome.org/PathwayBrowser/#/R-XTR-6781840 ERCC6 binds stalled RNA Pol II IEA Xenopus tropicalis 61120 R-XTR-6781867 https://reactome.org/PathwayBrowser/#/R-XTR-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Xenopus tropicalis 61120 R-XTR-6782069 https://reactome.org/PathwayBrowser/#/R-XTR-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Xenopus tropicalis 61120 R-XTR-6782131 https://reactome.org/PathwayBrowser/#/R-XTR-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Xenopus tropicalis 61120 R-XTR-6782204 https://reactome.org/PathwayBrowser/#/R-XTR-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Xenopus tropicalis 61120 R-XTR-6782208 https://reactome.org/PathwayBrowser/#/R-XTR-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Xenopus tropicalis 61120 R-XTR-6782211 https://reactome.org/PathwayBrowser/#/R-XTR-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Xenopus tropicalis 61120 R-XTR-6782227 https://reactome.org/PathwayBrowser/#/R-XTR-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Xenopus tropicalis 61120 R-XTR-6782943 https://reactome.org/PathwayBrowser/#/R-XTR-6782943 UV-DDB ubiquitinates XPC IEA Xenopus tropicalis 61120 R-XTR-6799332 https://reactome.org/PathwayBrowser/#/R-XTR-6799332 ATR phosphorylates TP53 IEA Xenopus tropicalis 61120 R-XTR-68944 https://reactome.org/PathwayBrowser/#/R-XTR-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Xenopus tropicalis 61120 R-XTR-68960 https://reactome.org/PathwayBrowser/#/R-XTR-68960 DNA polymerase epsilon binds at the origin IEA Xenopus tropicalis 61120 R-XTR-73718 https://reactome.org/PathwayBrowser/#/R-XTR-73718 UBF-1 Binds rDNA Promoter IEA Xenopus tropicalis 61120 R-XTR-73739 https://reactome.org/PathwayBrowser/#/R-XTR-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Xenopus tropicalis 61120 R-XTR-73769 https://reactome.org/PathwayBrowser/#/R-XTR-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Xenopus tropicalis 61120 R-XTR-75095 https://reactome.org/PathwayBrowser/#/R-XTR-75095 Binding of TFIIE to the growing preinitiation complex IEA Xenopus tropicalis 61120 R-XTR-75850 https://reactome.org/PathwayBrowser/#/R-XTR-75850 Addition of the third nucleotide on the nascent transcript IEA Xenopus tropicalis 61120 R-XTR-75861 https://reactome.org/PathwayBrowser/#/R-XTR-75861 NTP Binds Active Site of RNA Polymerase II IEA Xenopus tropicalis 61120 R-XTR-75862 https://reactome.org/PathwayBrowser/#/R-XTR-75862 Fall Back to Closed Pre-initiation Complex IEA Xenopus tropicalis 61120 R-XTR-75864 https://reactome.org/PathwayBrowser/#/R-XTR-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Xenopus tropicalis 61120 R-XTR-75866 https://reactome.org/PathwayBrowser/#/R-XTR-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Xenopus tropicalis 61120 R-XTR-75869 https://reactome.org/PathwayBrowser/#/R-XTR-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Xenopus tropicalis 61120 R-XTR-75891 https://reactome.org/PathwayBrowser/#/R-XTR-75891 Abortive Initiation After Second Transition IEA Xenopus tropicalis 61120 R-XTR-75949 https://reactome.org/PathwayBrowser/#/R-XTR-75949 RNA Polymerase II Promoter Opening: First Transition IEA Xenopus tropicalis 61120 R-XTR-76052 https://reactome.org/PathwayBrowser/#/R-XTR-76052 Binding of TFIIIA To type 1 Promoter IEA Xenopus tropicalis 61120 R-XTR-76054 https://reactome.org/PathwayBrowser/#/R-XTR-76054 Binding of TFIIIC to TFIIIA:Type I Promoter complex IEA Xenopus tropicalis 61120 R-XTR-76056 https://reactome.org/PathwayBrowser/#/R-XTR-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Xenopus tropicalis 61120 R-XTR-76576 https://reactome.org/PathwayBrowser/#/R-XTR-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Xenopus tropicalis 61120 R-XTR-77068 https://reactome.org/PathwayBrowser/#/R-XTR-77068 Activation of GT IEA Xenopus tropicalis 61120 R-XTR-77069 https://reactome.org/PathwayBrowser/#/R-XTR-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Xenopus tropicalis 61120 R-XTR-77071 https://reactome.org/PathwayBrowser/#/R-XTR-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Xenopus tropicalis 61120 R-XTR-77077 https://reactome.org/PathwayBrowser/#/R-XTR-77077 Capping complex formation IEA Xenopus tropicalis 61120 R-XTR-77078 https://reactome.org/PathwayBrowser/#/R-XTR-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Xenopus tropicalis 61120 R-XTR-77081 https://reactome.org/PathwayBrowser/#/R-XTR-77081 Formation of the CE:GMP intermediate complex IEA Xenopus tropicalis 61120 R-XTR-77083 https://reactome.org/PathwayBrowser/#/R-XTR-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Xenopus tropicalis 61120 R-XTR-77085 https://reactome.org/PathwayBrowser/#/R-XTR-77085 Dissociation of transcript with 5'-GMP from GT IEA Xenopus tropicalis 61120 R-XTR-83788 https://reactome.org/PathwayBrowser/#/R-XTR-83788 Binding of TFIIIC to Type 2 promoter IEA Xenopus tropicalis 61120 R-XTR-83805 https://reactome.org/PathwayBrowser/#/R-XTR-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Xenopus tropicalis 61120 R-XTR-9604487 https://reactome.org/PathwayBrowser/#/R-XTR-9604487 p-IRF7:p-IRF7 translocates to the nucleus IEA Xenopus tropicalis 61120 R-XTR-9613494 https://reactome.org/PathwayBrowser/#/R-XTR-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Xenopus tropicalis 61120 R-XTR-9613497 https://reactome.org/PathwayBrowser/#/R-XTR-9613497 Unwinding DNA for the nascent transcript IEA Xenopus tropicalis 61120 R-XTR-9684118 https://reactome.org/PathwayBrowser/#/R-XTR-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Xenopus tropicalis 61120 R-XTR-9734475 https://reactome.org/PathwayBrowser/#/R-XTR-9734475 PPARA binds fibrates IEA Xenopus tropicalis 61120 R-XTR-996727 https://reactome.org/PathwayBrowser/#/R-XTR-996727 REST recruits the BHC complex IEA Xenopus tropicalis 61168 R-HSA-1222325 https://reactome.org/PathwayBrowser/#/R-HSA-1222325 Carboxymycobactin and mycobactin exchange their iron load TAS Homo sapiens 61168 R-HSA-1222399 https://reactome.org/PathwayBrowser/#/R-HSA-1222399 Iron is reduced and separates from mycobactin IEA Homo sapiens 61168 R-HSA-1222597 https://reactome.org/PathwayBrowser/#/R-HSA-1222597 Loaded mycobactin gets imported TAS Homo sapiens 61168 R-HSA-1222722 https://reactome.org/PathwayBrowser/#/R-HSA-1222722 Mycobactin is exported TAS Homo sapiens 61185 R-BTA-5693347 https://reactome.org/PathwayBrowser/#/R-BTA-5693347 CRYM reduces P2C to PPCA IEA Bos taurus 61185 R-BTA-6783880 https://reactome.org/PathwayBrowser/#/R-BTA-6783880 PIPOX oxidises PPCA to P6C IEA Bos taurus 61185 R-CEL-6783880 https://reactome.org/PathwayBrowser/#/R-CEL-6783880 PIPOX oxidises PPCA to P6C IEA Caenorhabditis elegans 61185 R-CFA-5693347 https://reactome.org/PathwayBrowser/#/R-CFA-5693347 CRYM reduces P2C to PPCA IEA Canis familiaris 61185 R-CFA-6783880 https://reactome.org/PathwayBrowser/#/R-CFA-6783880 PIPOX oxidises PPCA to P6C IEA Canis familiaris 61185 R-DDI-5693347 https://reactome.org/PathwayBrowser/#/R-DDI-5693347 CRYM reduces P2C to PPCA IEA Dictyostelium discoideum 61185 R-DDI-6783880 https://reactome.org/PathwayBrowser/#/R-DDI-6783880 PIPOX oxidises PPCA to P6C IEA Dictyostelium discoideum 61185 R-DME-5693347 https://reactome.org/PathwayBrowser/#/R-DME-5693347 CRYM reduces P2C to PPCA IEA Drosophila melanogaster 61185 R-DRE-5693347 https://reactome.org/PathwayBrowser/#/R-DRE-5693347 CRYM reduces P2C to PPCA IEA Danio rerio 61185 R-GGA-5693347 https://reactome.org/PathwayBrowser/#/R-GGA-5693347 CRYM reduces P2C to PPCA IEA Gallus gallus 61185 R-GGA-6783880 https://reactome.org/PathwayBrowser/#/R-GGA-6783880 PIPOX oxidises PPCA to P6C IEA Gallus gallus 61185 R-HSA-5693347 https://reactome.org/PathwayBrowser/#/R-HSA-5693347 CRYM reduces P2C to PPCA TAS Homo sapiens 61185 R-HSA-6783880 https://reactome.org/PathwayBrowser/#/R-HSA-6783880 PIPOX oxidises PPCA to P6C TAS Homo sapiens 61185 R-MMU-5693347 https://reactome.org/PathwayBrowser/#/R-MMU-5693347 CRYM reduces P2C to PPCA IEA Mus musculus 61185 R-MMU-6783880 https://reactome.org/PathwayBrowser/#/R-MMU-6783880 PIPOX oxidises PPCA to P6C IEA Mus musculus 61185 R-RNO-5693347 https://reactome.org/PathwayBrowser/#/R-RNO-5693347 CRYM reduces P2C to PPCA IEA Rattus norvegicus 61185 R-RNO-6783880 https://reactome.org/PathwayBrowser/#/R-RNO-6783880 PIPOX oxidises PPCA to P6C IEA Rattus norvegicus 61185 R-SCE-5693347 https://reactome.org/PathwayBrowser/#/R-SCE-5693347 CRYM reduces P2C to PPCA IEA Saccharomyces cerevisiae 61185 R-SPO-5693347 https://reactome.org/PathwayBrowser/#/R-SPO-5693347 CRYM reduces P2C to PPCA IEA Schizosaccharomyces pombe 61185 R-SPO-6783880 https://reactome.org/PathwayBrowser/#/R-SPO-6783880 PIPOX oxidises PPCA to P6C IEA Schizosaccharomyces pombe 61185 R-SSC-5693347 https://reactome.org/PathwayBrowser/#/R-SSC-5693347 CRYM reduces P2C to PPCA IEA Sus scrofa 61185 R-SSC-6783880 https://reactome.org/PathwayBrowser/#/R-SSC-6783880 PIPOX oxidises PPCA to P6C IEA Sus scrofa 61185 R-XTR-5693347 https://reactome.org/PathwayBrowser/#/R-XTR-5693347 CRYM reduces P2C to PPCA IEA Xenopus tropicalis 61185 R-XTR-6783880 https://reactome.org/PathwayBrowser/#/R-XTR-6783880 PIPOX oxidises PPCA to P6C IEA Xenopus tropicalis 61194 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 61194 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 61194 R-BTA-2509793 https://reactome.org/PathwayBrowser/#/R-BTA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Bos taurus 61194 R-BTA-2509838 https://reactome.org/PathwayBrowser/#/R-BTA-2509838 ITPA hydrolyses dITP to dIMP IEA Bos taurus 61194 R-BTA-74207 https://reactome.org/PathwayBrowser/#/R-BTA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Bos taurus 61194 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 61194 R-BTA-9731661 https://reactome.org/PathwayBrowser/#/R-BTA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Bos taurus 61194 R-CEL-2509838 https://reactome.org/PathwayBrowser/#/R-CEL-2509838 ITPA hydrolyses dITP to dIMP IEA Caenorhabditis elegans 61194 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 61194 R-CEL-9731661 https://reactome.org/PathwayBrowser/#/R-CEL-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Caenorhabditis elegans 61194 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 61194 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 61194 R-CFA-2509793 https://reactome.org/PathwayBrowser/#/R-CFA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Canis familiaris 61194 R-CFA-2509838 https://reactome.org/PathwayBrowser/#/R-CFA-2509838 ITPA hydrolyses dITP to dIMP IEA Canis familiaris 61194 R-CFA-74207 https://reactome.org/PathwayBrowser/#/R-CFA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Canis familiaris 61194 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 61194 R-CFA-9731661 https://reactome.org/PathwayBrowser/#/R-CFA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Canis familiaris 61194 R-DDI-2509838 https://reactome.org/PathwayBrowser/#/R-DDI-2509838 ITPA hydrolyses dITP to dIMP IEA Dictyostelium discoideum 61194 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 61194 R-DME-2509838 https://reactome.org/PathwayBrowser/#/R-DME-2509838 ITPA hydrolyses dITP to dIMP IEA Drosophila melanogaster 61194 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 61194 R-DME-9731661 https://reactome.org/PathwayBrowser/#/R-DME-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Drosophila melanogaster 61194 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 61194 R-DRE-2509793 https://reactome.org/PathwayBrowser/#/R-DRE-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Danio rerio 61194 R-DRE-2509838 https://reactome.org/PathwayBrowser/#/R-DRE-2509838 ITPA hydrolyses dITP to dIMP IEA Danio rerio 61194 R-DRE-74207 https://reactome.org/PathwayBrowser/#/R-DRE-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Danio rerio 61194 R-DRE-9731661 https://reactome.org/PathwayBrowser/#/R-DRE-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Danio rerio 61194 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 61194 R-GGA-2509838 https://reactome.org/PathwayBrowser/#/R-GGA-2509838 ITPA hydrolyses dITP to dIMP IEA Gallus gallus 61194 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 61194 R-GGA-9731661 https://reactome.org/PathwayBrowser/#/R-GGA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Gallus gallus 61194 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 61194 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 61194 R-HSA-2509793 https://reactome.org/PathwayBrowser/#/R-HSA-2509793 NUDT16 hydrolyses dIDP to dIMP TAS Homo sapiens 61194 R-HSA-2509838 https://reactome.org/PathwayBrowser/#/R-HSA-2509838 ITPA hydrolyses dITP to dIMP TAS Homo sapiens 61194 R-HSA-74207 https://reactome.org/PathwayBrowser/#/R-HSA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) TAS Homo sapiens 61194 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 61194 R-HSA-9731661 https://reactome.org/PathwayBrowser/#/R-HSA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine TAS Homo sapiens 61194 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 61194 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 61194 R-MMU-2509793 https://reactome.org/PathwayBrowser/#/R-MMU-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Mus musculus 61194 R-MMU-2509838 https://reactome.org/PathwayBrowser/#/R-MMU-2509838 ITPA hydrolyses dITP to dIMP IEA Mus musculus 61194 R-MMU-74207 https://reactome.org/PathwayBrowser/#/R-MMU-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Mus musculus 61194 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 61194 R-MMU-9731661 https://reactome.org/PathwayBrowser/#/R-MMU-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Mus musculus 61194 R-PFA-2509838 https://reactome.org/PathwayBrowser/#/R-PFA-2509838 ITPA hydrolyses dITP to dIMP IEA Plasmodium falciparum 61194 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 61194 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 61194 R-RNO-2509793 https://reactome.org/PathwayBrowser/#/R-RNO-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Rattus norvegicus 61194 R-RNO-2509838 https://reactome.org/PathwayBrowser/#/R-RNO-2509838 ITPA hydrolyses dITP to dIMP IEA Rattus norvegicus 61194 R-RNO-74207 https://reactome.org/PathwayBrowser/#/R-RNO-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Rattus norvegicus 61194 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 61194 R-SCE-2509838 https://reactome.org/PathwayBrowser/#/R-SCE-2509838 ITPA hydrolyses dITP to dIMP IEA Saccharomyces cerevisiae 61194 R-SPO-2509838 https://reactome.org/PathwayBrowser/#/R-SPO-2509838 ITPA hydrolyses dITP to dIMP IEA Schizosaccharomyces pombe 61194 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 61194 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 61194 R-SSC-2509793 https://reactome.org/PathwayBrowser/#/R-SSC-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Sus scrofa 61194 R-SSC-2509838 https://reactome.org/PathwayBrowser/#/R-SSC-2509838 ITPA hydrolyses dITP to dIMP IEA Sus scrofa 61194 R-SSC-74207 https://reactome.org/PathwayBrowser/#/R-SSC-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Sus scrofa 61194 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 61194 R-SSC-9731661 https://reactome.org/PathwayBrowser/#/R-SSC-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Sus scrofa 61194 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 61194 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 61194 R-XTR-2509793 https://reactome.org/PathwayBrowser/#/R-XTR-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Xenopus tropicalis 61194 R-XTR-2509838 https://reactome.org/PathwayBrowser/#/R-XTR-2509838 ITPA hydrolyses dITP to dIMP IEA Xenopus tropicalis 61194 R-XTR-74207 https://reactome.org/PathwayBrowser/#/R-XTR-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Xenopus tropicalis 61194 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 61194 R-XTR-9731661 https://reactome.org/PathwayBrowser/#/R-XTR-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Xenopus tropicalis 61232 R-BTA-5694583 https://reactome.org/PathwayBrowser/#/R-BTA-5694583 ABHD4 hydrolyses NAPE IEA Bos taurus 61232 R-BTA-8858298 https://reactome.org/PathwayBrowser/#/R-BTA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Bos taurus 61232 R-CEL-5694583 https://reactome.org/PathwayBrowser/#/R-CEL-5694583 ABHD4 hydrolyses NAPE IEA Caenorhabditis elegans 61232 R-CFA-5694583 https://reactome.org/PathwayBrowser/#/R-CFA-5694583 ABHD4 hydrolyses NAPE IEA Canis familiaris 61232 R-CFA-8858298 https://reactome.org/PathwayBrowser/#/R-CFA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Canis familiaris 61232 R-DME-5694583 https://reactome.org/PathwayBrowser/#/R-DME-5694583 ABHD4 hydrolyses NAPE IEA Drosophila melanogaster 61232 R-DRE-8858298 https://reactome.org/PathwayBrowser/#/R-DRE-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Danio rerio 61232 R-HSA-5694583 https://reactome.org/PathwayBrowser/#/R-HSA-5694583 ABHD4 hydrolyses NAPE TAS Homo sapiens 61232 R-HSA-8858298 https://reactome.org/PathwayBrowser/#/R-HSA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE TAS Homo sapiens 61232 R-MMU-5694583 https://reactome.org/PathwayBrowser/#/R-MMU-5694583 ABHD4 hydrolyses NAPE IEA Mus musculus 61232 R-MMU-8858298 https://reactome.org/PathwayBrowser/#/R-MMU-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Mus musculus 61232 R-RNO-5694583 https://reactome.org/PathwayBrowser/#/R-RNO-5694583 ABHD4 hydrolyses NAPE IEA Rattus norvegicus 61232 R-RNO-8858298 https://reactome.org/PathwayBrowser/#/R-RNO-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Rattus norvegicus 61232 R-SCE-5694583 https://reactome.org/PathwayBrowser/#/R-SCE-5694583 ABHD4 hydrolyses NAPE IEA Saccharomyces cerevisiae 61232 R-SPO-5694583 https://reactome.org/PathwayBrowser/#/R-SPO-5694583 ABHD4 hydrolyses NAPE IEA Schizosaccharomyces pombe 61232 R-SSC-5694583 https://reactome.org/PathwayBrowser/#/R-SSC-5694583 ABHD4 hydrolyses NAPE IEA Sus scrofa 61232 R-SSC-8858298 https://reactome.org/PathwayBrowser/#/R-SSC-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Sus scrofa 61232 R-XTR-5694583 https://reactome.org/PathwayBrowser/#/R-XTR-5694583 ABHD4 hydrolyses NAPE IEA Xenopus tropicalis 61232 R-XTR-8858298 https://reactome.org/PathwayBrowser/#/R-XTR-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Xenopus tropicalis 61248 R-BTA-4084984 https://reactome.org/PathwayBrowser/#/R-BTA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Bos taurus 61248 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 61248 R-BTA-4084999 https://reactome.org/PathwayBrowser/#/R-BTA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 61248 R-BTA-4085029 https://reactome.org/PathwayBrowser/#/R-BTA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 61248 R-BTA-4085033 https://reactome.org/PathwayBrowser/#/R-BTA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Bos taurus 61248 R-BTA-9638120 https://reactome.org/PathwayBrowser/#/R-BTA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 61248 R-CFA-4084984 https://reactome.org/PathwayBrowser/#/R-CFA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Canis familiaris 61248 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 61248 R-CFA-4084999 https://reactome.org/PathwayBrowser/#/R-CFA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 61248 R-CFA-4085029 https://reactome.org/PathwayBrowser/#/R-CFA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 61248 R-CFA-4085033 https://reactome.org/PathwayBrowser/#/R-CFA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Canis familiaris 61248 R-CFA-9638120 https://reactome.org/PathwayBrowser/#/R-CFA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 61248 R-DME-4085033 https://reactome.org/PathwayBrowser/#/R-DME-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Drosophila melanogaster 61248 R-DRE-4084984 https://reactome.org/PathwayBrowser/#/R-DRE-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Danio rerio 61248 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 61248 R-DRE-4085029 https://reactome.org/PathwayBrowser/#/R-DRE-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 61248 R-DRE-4085033 https://reactome.org/PathwayBrowser/#/R-DRE-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Danio rerio 61248 R-GGA-4084984 https://reactome.org/PathwayBrowser/#/R-GGA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Gallus gallus 61248 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 61248 R-GGA-4085029 https://reactome.org/PathwayBrowser/#/R-GGA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 61248 R-GGA-4085033 https://reactome.org/PathwayBrowser/#/R-GGA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Gallus gallus 61248 R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus 61248 R-HSA-4084984 https://reactome.org/PathwayBrowser/#/R-HSA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) TAS Homo sapiens 61248 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 61248 R-HSA-4084999 https://reactome.org/PathwayBrowser/#/R-HSA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 61248 R-HSA-4085029 https://reactome.org/PathwayBrowser/#/R-HSA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 61248 R-HSA-4085033 https://reactome.org/PathwayBrowser/#/R-HSA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) TAS Homo sapiens 61248 R-HSA-9638120 https://reactome.org/PathwayBrowser/#/R-HSA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 61248 R-MMU-4084984 https://reactome.org/PathwayBrowser/#/R-MMU-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Mus musculus 61248 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 61248 R-MMU-4084999 https://reactome.org/PathwayBrowser/#/R-MMU-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 61248 R-MMU-4085029 https://reactome.org/PathwayBrowser/#/R-MMU-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 61248 R-MMU-4085033 https://reactome.org/PathwayBrowser/#/R-MMU-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Mus musculus 61248 R-MMU-9638120 https://reactome.org/PathwayBrowser/#/R-MMU-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 61248 R-RNO-4084984 https://reactome.org/PathwayBrowser/#/R-RNO-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Rattus norvegicus 61248 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 61248 R-RNO-4084999 https://reactome.org/PathwayBrowser/#/R-RNO-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 61248 R-RNO-4085029 https://reactome.org/PathwayBrowser/#/R-RNO-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 61248 R-RNO-4085033 https://reactome.org/PathwayBrowser/#/R-RNO-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Rattus norvegicus 61248 R-RNO-9638120 https://reactome.org/PathwayBrowser/#/R-RNO-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 61248 R-SSC-4084984 https://reactome.org/PathwayBrowser/#/R-SSC-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Sus scrofa 61248 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 61248 R-SSC-4084999 https://reactome.org/PathwayBrowser/#/R-SSC-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 61248 R-SSC-4085029 https://reactome.org/PathwayBrowser/#/R-SSC-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 61248 R-SSC-4085033 https://reactome.org/PathwayBrowser/#/R-SSC-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Sus scrofa 61248 R-SSC-9638120 https://reactome.org/PathwayBrowser/#/R-SSC-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 61248 R-XTR-4084984 https://reactome.org/PathwayBrowser/#/R-XTR-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Xenopus tropicalis 61248 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 61248 R-XTR-4084999 https://reactome.org/PathwayBrowser/#/R-XTR-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 61248 R-XTR-4085029 https://reactome.org/PathwayBrowser/#/R-XTR-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 61248 R-XTR-4085033 https://reactome.org/PathwayBrowser/#/R-XTR-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Xenopus tropicalis 61248 R-XTR-9638120 https://reactome.org/PathwayBrowser/#/R-XTR-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 61314 R-BTA-2509831 https://reactome.org/PathwayBrowser/#/R-BTA-2509831 ITPA hydrolyses XTP to XMP IEA Bos taurus 61314 R-CEL-2509831 https://reactome.org/PathwayBrowser/#/R-CEL-2509831 ITPA hydrolyses XTP to XMP IEA Caenorhabditis elegans 61314 R-CFA-2509831 https://reactome.org/PathwayBrowser/#/R-CFA-2509831 ITPA hydrolyses XTP to XMP IEA Canis familiaris 61314 R-DDI-2509831 https://reactome.org/PathwayBrowser/#/R-DDI-2509831 ITPA hydrolyses XTP to XMP IEA Dictyostelium discoideum 61314 R-DME-2509831 https://reactome.org/PathwayBrowser/#/R-DME-2509831 ITPA hydrolyses XTP to XMP IEA Drosophila melanogaster 61314 R-DRE-2509831 https://reactome.org/PathwayBrowser/#/R-DRE-2509831 ITPA hydrolyses XTP to XMP IEA Danio rerio 61314 R-GGA-2509831 https://reactome.org/PathwayBrowser/#/R-GGA-2509831 ITPA hydrolyses XTP to XMP IEA Gallus gallus 61314 R-HSA-2509831 https://reactome.org/PathwayBrowser/#/R-HSA-2509831 ITPA hydrolyses XTP to XMP TAS Homo sapiens 61314 R-MMU-2509831 https://reactome.org/PathwayBrowser/#/R-MMU-2509831 ITPA hydrolyses XTP to XMP IEA Mus musculus 61314 R-PFA-2509831 https://reactome.org/PathwayBrowser/#/R-PFA-2509831 ITPA hydrolyses XTP to XMP IEA Plasmodium falciparum 61314 R-RNO-2509831 https://reactome.org/PathwayBrowser/#/R-RNO-2509831 ITPA hydrolyses XTP to XMP IEA Rattus norvegicus 61314 R-SCE-2509831 https://reactome.org/PathwayBrowser/#/R-SCE-2509831 ITPA hydrolyses XTP to XMP IEA Saccharomyces cerevisiae 61314 R-SPO-2509831 https://reactome.org/PathwayBrowser/#/R-SPO-2509831 ITPA hydrolyses XTP to XMP IEA Schizosaccharomyces pombe 61314 R-SSC-2509831 https://reactome.org/PathwayBrowser/#/R-SSC-2509831 ITPA hydrolyses XTP to XMP IEA Sus scrofa 61314 R-XTR-2509831 https://reactome.org/PathwayBrowser/#/R-XTR-2509831 ITPA hydrolyses XTP to XMP IEA Xenopus tropicalis 61334 R-BTA-9603982 https://reactome.org/PathwayBrowser/#/R-BTA-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Bos taurus 61334 R-BTA-9603986 https://reactome.org/PathwayBrowser/#/R-BTA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Bos taurus 61334 R-CEL-9603982 https://reactome.org/PathwayBrowser/#/R-CEL-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Caenorhabditis elegans 61334 R-CEL-9603986 https://reactome.org/PathwayBrowser/#/R-CEL-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Caenorhabditis elegans 61334 R-CFA-9603982 https://reactome.org/PathwayBrowser/#/R-CFA-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Canis familiaris 61334 R-CFA-9603986 https://reactome.org/PathwayBrowser/#/R-CFA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Canis familiaris 61334 R-DDI-9603986 https://reactome.org/PathwayBrowser/#/R-DDI-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Dictyostelium discoideum 61334 R-DME-9603986 https://reactome.org/PathwayBrowser/#/R-DME-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Drosophila melanogaster 61334 R-HSA-9603982 https://reactome.org/PathwayBrowser/#/R-HSA-9603982 FUT2 transfers Fuc to LeA to form LeB TAS Homo sapiens 61334 R-HSA-9603986 https://reactome.org/PathwayBrowser/#/R-HSA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA TAS Homo sapiens 61334 R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 61334 R-MMU-9603982 https://reactome.org/PathwayBrowser/#/R-MMU-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Mus musculus 61334 R-RNO-9603982 https://reactome.org/PathwayBrowser/#/R-RNO-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Rattus norvegicus 61334 R-SSC-9603982 https://reactome.org/PathwayBrowser/#/R-SSC-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Sus scrofa 61334 R-SSC-9603986 https://reactome.org/PathwayBrowser/#/R-SSC-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Sus scrofa 61334 R-XTR-9603982 https://reactome.org/PathwayBrowser/#/R-XTR-9603982 FUT2 transfers Fuc to LeA to form LeB IEA Xenopus tropicalis 61334 R-XTR-9603986 https://reactome.org/PathwayBrowser/#/R-XTR-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Xenopus tropicalis 61382 R-BTA-2509838 https://reactome.org/PathwayBrowser/#/R-BTA-2509838 ITPA hydrolyses dITP to dIMP IEA Bos taurus 61382 R-CEL-2509838 https://reactome.org/PathwayBrowser/#/R-CEL-2509838 ITPA hydrolyses dITP to dIMP IEA Caenorhabditis elegans 61382 R-CFA-2509838 https://reactome.org/PathwayBrowser/#/R-CFA-2509838 ITPA hydrolyses dITP to dIMP IEA Canis familiaris 61382 R-DDI-2509838 https://reactome.org/PathwayBrowser/#/R-DDI-2509838 ITPA hydrolyses dITP to dIMP IEA Dictyostelium discoideum 61382 R-DME-2509838 https://reactome.org/PathwayBrowser/#/R-DME-2509838 ITPA hydrolyses dITP to dIMP IEA Drosophila melanogaster 61382 R-DRE-2509838 https://reactome.org/PathwayBrowser/#/R-DRE-2509838 ITPA hydrolyses dITP to dIMP IEA Danio rerio 61382 R-GGA-2509838 https://reactome.org/PathwayBrowser/#/R-GGA-2509838 ITPA hydrolyses dITP to dIMP IEA Gallus gallus 61382 R-HSA-2509838 https://reactome.org/PathwayBrowser/#/R-HSA-2509838 ITPA hydrolyses dITP to dIMP TAS Homo sapiens 61382 R-MMU-2509838 https://reactome.org/PathwayBrowser/#/R-MMU-2509838 ITPA hydrolyses dITP to dIMP IEA Mus musculus 61382 R-PFA-2509838 https://reactome.org/PathwayBrowser/#/R-PFA-2509838 ITPA hydrolyses dITP to dIMP IEA Plasmodium falciparum 61382 R-RNO-2509838 https://reactome.org/PathwayBrowser/#/R-RNO-2509838 ITPA hydrolyses dITP to dIMP IEA Rattus norvegicus 61382 R-SCE-2509838 https://reactome.org/PathwayBrowser/#/R-SCE-2509838 ITPA hydrolyses dITP to dIMP IEA Saccharomyces cerevisiae 61382 R-SPO-2509838 https://reactome.org/PathwayBrowser/#/R-SPO-2509838 ITPA hydrolyses dITP to dIMP IEA Schizosaccharomyces pombe 61382 R-SSC-2509838 https://reactome.org/PathwayBrowser/#/R-SSC-2509838 ITPA hydrolyses dITP to dIMP IEA Sus scrofa 61382 R-XTR-2509838 https://reactome.org/PathwayBrowser/#/R-XTR-2509838 ITPA hydrolyses dITP to dIMP IEA Xenopus tropicalis 61390 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 61390 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 61390 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 61390 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 61390 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 61390 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 61390 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 61390 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 61390 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 61390 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 61390 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 61390 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 61390 R-HSA-1220611 https://reactome.org/PathwayBrowser/#/R-HSA-1220611 Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors TAS Homo sapiens 61390 R-HSA-1225978 https://reactome.org/PathwayBrowser/#/R-HSA-1225978 Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers TAS Homo sapiens 61390 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 61390 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 61390 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 61390 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 61390 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 61390 R-HSA-9665286 https://reactome.org/PathwayBrowser/#/R-HSA-9665286 Resistant ERBB2 KD mutants do not bind neratinib TAS Homo sapiens 61390 R-HSA-9665311 https://reactome.org/PathwayBrowser/#/R-HSA-9665311 ERBB2 T798M does not bind afatinib TAS Homo sapiens 61390 R-HSA-9665389 https://reactome.org/PathwayBrowser/#/R-HSA-9665389 Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate TAS Homo sapiens 61390 R-HSA-9665412 https://reactome.org/PathwayBrowser/#/R-HSA-9665412 ERBB2 ECD mutants bind TKIs TAS Homo sapiens 61390 R-HSA-9665702 https://reactome.org/PathwayBrowser/#/R-HSA-9665702 ERBB2 TMD/JMD mutants bind TKIs TAS Homo sapiens 61390 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 61390 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 61390 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 61390 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 61390 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 61390 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 61399 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 61399 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 61399 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 61399 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 61399 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 61399 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 61399 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 61399 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 61399 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 61399 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 61399 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 61399 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 61399 R-HSA-1220611 https://reactome.org/PathwayBrowser/#/R-HSA-1220611 Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors TAS Homo sapiens 61399 R-HSA-1225978 https://reactome.org/PathwayBrowser/#/R-HSA-1225978 Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers TAS Homo sapiens 61399 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 61399 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 61399 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 61399 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 61399 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 61399 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 61399 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 61399 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 61399 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 61399 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 61399 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 61400 R-HSA-1220611 https://reactome.org/PathwayBrowser/#/R-HSA-1220611 Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors TAS Homo sapiens 61400 R-HSA-1225978 https://reactome.org/PathwayBrowser/#/R-HSA-1225978 Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers TAS Homo sapiens 61402 R-BTA-2509827 https://reactome.org/PathwayBrowser/#/R-BTA-2509827 ITPA hydrolyses ITP to IMP IEA Bos taurus 61402 R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 61402 R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 61402 R-CEL-2509827 https://reactome.org/PathwayBrowser/#/R-CEL-2509827 ITPA hydrolyses ITP to IMP IEA Caenorhabditis elegans 61402 R-CFA-2509827 https://reactome.org/PathwayBrowser/#/R-CFA-2509827 ITPA hydrolyses ITP to IMP IEA Canis familiaris 61402 R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 61402 R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 61402 R-DDI-2509827 https://reactome.org/PathwayBrowser/#/R-DDI-2509827 ITPA hydrolyses ITP to IMP IEA Dictyostelium discoideum 61402 R-DME-2509827 https://reactome.org/PathwayBrowser/#/R-DME-2509827 ITPA hydrolyses ITP to IMP IEA Drosophila melanogaster 61402 R-DRE-2509827 https://reactome.org/PathwayBrowser/#/R-DRE-2509827 ITPA hydrolyses ITP to IMP IEA Danio rerio 61402 R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 61402 R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 61402 R-GGA-2509827 https://reactome.org/PathwayBrowser/#/R-GGA-2509827 ITPA hydrolyses ITP to IMP IEA Gallus gallus 61402 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 61402 R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 61402 R-HSA-2509827 https://reactome.org/PathwayBrowser/#/R-HSA-2509827 ITPA hydrolyses ITP to IMP TAS Homo sapiens 61402 R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 61402 R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 61402 R-MMU-2509827 https://reactome.org/PathwayBrowser/#/R-MMU-2509827 ITPA hydrolyses ITP to IMP IEA Mus musculus 61402 R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 61402 R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 61402 R-PFA-2509827 https://reactome.org/PathwayBrowser/#/R-PFA-2509827 ITPA hydrolyses ITP to IMP IEA Plasmodium falciparum 61402 R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 61402 R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 61402 R-RNO-2509827 https://reactome.org/PathwayBrowser/#/R-RNO-2509827 ITPA hydrolyses ITP to IMP IEA Rattus norvegicus 61402 R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 61402 R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 61402 R-SCE-2509827 https://reactome.org/PathwayBrowser/#/R-SCE-2509827 ITPA hydrolyses ITP to IMP IEA Saccharomyces cerevisiae 61402 R-SPO-2509827 https://reactome.org/PathwayBrowser/#/R-SPO-2509827 ITPA hydrolyses ITP to IMP IEA Schizosaccharomyces pombe 61402 R-SSC-2509827 https://reactome.org/PathwayBrowser/#/R-SSC-2509827 ITPA hydrolyses ITP to IMP IEA Sus scrofa 61402 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 61402 R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 61402 R-XTR-2509827 https://reactome.org/PathwayBrowser/#/R-XTR-2509827 ITPA hydrolyses ITP to IMP IEA Xenopus tropicalis 61402 R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 61402 R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 61404 R-BTA-110317 https://reactome.org/PathwayBrowser/#/R-BTA-110317 Insertion of correct bases opposite the lesion by POLH IEA Bos taurus 61404 R-BTA-111215 https://reactome.org/PathwayBrowser/#/R-BTA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Bos taurus 61404 R-BTA-111742 https://reactome.org/PathwayBrowser/#/R-BTA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 61404 R-BTA-111751 https://reactome.org/PathwayBrowser/#/R-BTA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 61404 R-BTA-111804 https://reactome.org/PathwayBrowser/#/R-BTA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 61404 R-BTA-163090 https://reactome.org/PathwayBrowser/#/R-BTA-163090 Elongation Of The Telomeric Chromosome End IEA Bos taurus 61404 R-BTA-164617 https://reactome.org/PathwayBrowser/#/R-BTA-164617 Elongation of Extended Telomeric Chromosome End IEA Bos taurus 61404 R-BTA-174427 https://reactome.org/PathwayBrowser/#/R-BTA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Bos taurus 61404 R-BTA-174444 https://reactome.org/PathwayBrowser/#/R-BTA-174444 Formation of C-strand Okazaki fragments IEA Bos taurus 61404 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 61404 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 61404 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 61404 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 61404 R-BTA-5358579 https://reactome.org/PathwayBrowser/#/R-BTA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Bos taurus 61404 R-BTA-68950 https://reactome.org/PathwayBrowser/#/R-BTA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Bos taurus 61404 R-BTA-8866405 https://reactome.org/PathwayBrowser/#/R-BTA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 61404 R-CEL-110317 https://reactome.org/PathwayBrowser/#/R-CEL-110317 Insertion of correct bases opposite the lesion by POLH IEA Caenorhabditis elegans 61404 R-CEL-111742 https://reactome.org/PathwayBrowser/#/R-CEL-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 61404 R-CEL-111751 https://reactome.org/PathwayBrowser/#/R-CEL-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 61404 R-CEL-111804 https://reactome.org/PathwayBrowser/#/R-CEL-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 61404 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 61404 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 61404 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 61404 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 61404 R-CEL-68950 https://reactome.org/PathwayBrowser/#/R-CEL-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Caenorhabditis elegans 61404 R-CEL-8866405 https://reactome.org/PathwayBrowser/#/R-CEL-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 61404 R-CFA-110317 https://reactome.org/PathwayBrowser/#/R-CFA-110317 Insertion of correct bases opposite the lesion by POLH IEA Canis familiaris 61404 R-CFA-111215 https://reactome.org/PathwayBrowser/#/R-CFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Canis familiaris 61404 R-CFA-111742 https://reactome.org/PathwayBrowser/#/R-CFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 61404 R-CFA-111751 https://reactome.org/PathwayBrowser/#/R-CFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 61404 R-CFA-111804 https://reactome.org/PathwayBrowser/#/R-CFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 61404 R-CFA-163090 https://reactome.org/PathwayBrowser/#/R-CFA-163090 Elongation Of The Telomeric Chromosome End IEA Canis familiaris 61404 R-CFA-164617 https://reactome.org/PathwayBrowser/#/R-CFA-164617 Elongation of Extended Telomeric Chromosome End IEA Canis familiaris 61404 R-CFA-174427 https://reactome.org/PathwayBrowser/#/R-CFA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Canis familiaris 61404 R-CFA-174444 https://reactome.org/PathwayBrowser/#/R-CFA-174444 Formation of C-strand Okazaki fragments IEA Canis familiaris 61404 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 61404 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 61404 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 61404 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 61404 R-CFA-5358579 https://reactome.org/PathwayBrowser/#/R-CFA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Canis familiaris 61404 R-CFA-68950 https://reactome.org/PathwayBrowser/#/R-CFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Canis familiaris 61404 R-CFA-8866405 https://reactome.org/PathwayBrowser/#/R-CFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 61404 R-DDI-111215 https://reactome.org/PathwayBrowser/#/R-DDI-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Dictyostelium discoideum 61404 R-DDI-111751 https://reactome.org/PathwayBrowser/#/R-DDI-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 61404 R-DDI-111804 https://reactome.org/PathwayBrowser/#/R-DDI-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 61404 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 61404 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 61404 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 61404 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 61404 R-DDI-68950 https://reactome.org/PathwayBrowser/#/R-DDI-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Dictyostelium discoideum 61404 R-DME-110317 https://reactome.org/PathwayBrowser/#/R-DME-110317 Insertion of correct bases opposite the lesion by POLH IEA Drosophila melanogaster 61404 R-DME-111751 https://reactome.org/PathwayBrowser/#/R-DME-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 61404 R-DME-111804 https://reactome.org/PathwayBrowser/#/R-DME-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 61404 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 61404 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 61404 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 61404 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 61404 R-DME-68950 https://reactome.org/PathwayBrowser/#/R-DME-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Drosophila melanogaster 61404 R-DRE-110317 https://reactome.org/PathwayBrowser/#/R-DRE-110317 Insertion of correct bases opposite the lesion by POLH IEA Danio rerio 61404 R-DRE-111215 https://reactome.org/PathwayBrowser/#/R-DRE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Danio rerio 61404 R-DRE-111742 https://reactome.org/PathwayBrowser/#/R-DRE-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 61404 R-DRE-111751 https://reactome.org/PathwayBrowser/#/R-DRE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 61404 R-DRE-111804 https://reactome.org/PathwayBrowser/#/R-DRE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 61404 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 61404 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 61404 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 61404 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 61404 R-DRE-8866405 https://reactome.org/PathwayBrowser/#/R-DRE-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 61404 R-GGA-110317 https://reactome.org/PathwayBrowser/#/R-GGA-110317 Insertion of correct bases opposite the lesion by POLH IEA Gallus gallus 61404 R-GGA-111215 https://reactome.org/PathwayBrowser/#/R-GGA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Gallus gallus 61404 R-GGA-163090 https://reactome.org/PathwayBrowser/#/R-GGA-163090 Elongation Of The Telomeric Chromosome End IEA Gallus gallus 61404 R-GGA-164617 https://reactome.org/PathwayBrowser/#/R-GGA-164617 Elongation of Extended Telomeric Chromosome End IEA Gallus gallus 61404 R-GGA-174427 https://reactome.org/PathwayBrowser/#/R-GGA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Gallus gallus 61404 R-GGA-417122 https://reactome.org/PathwayBrowser/#/R-GGA-417122 Elongation and translocation of the telomeric chromosome end IEA Gallus gallus 61404 R-GGA-417127 https://reactome.org/PathwayBrowser/#/R-GGA-417127 Elongation and translocation of the extended telomeric chromosome end IEA Gallus gallus 61404 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 61404 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 61404 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 61404 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 61404 R-GGA-68950 https://reactome.org/PathwayBrowser/#/R-GGA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Gallus gallus 61404 R-HSA-110317 https://reactome.org/PathwayBrowser/#/R-HSA-110317 Insertion of correct bases opposite the lesion by POLH TAS Homo sapiens 61404 R-HSA-111215 https://reactome.org/PathwayBrowser/#/R-HSA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate TAS Homo sapiens 61404 R-HSA-111742 https://reactome.org/PathwayBrowser/#/R-HSA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 61404 R-HSA-111751 https://reactome.org/PathwayBrowser/#/R-HSA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 61404 R-HSA-111804 https://reactome.org/PathwayBrowser/#/R-HSA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 61404 R-HSA-163090 https://reactome.org/PathwayBrowser/#/R-HSA-163090 Elongation Of The Telomeric Chromosome End TAS Homo sapiens 61404 R-HSA-164617 https://reactome.org/PathwayBrowser/#/R-HSA-164617 Elongation of Extended Telomeric Chromosome End TAS Homo sapiens 61404 R-HSA-174427 https://reactome.org/PathwayBrowser/#/R-HSA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere TAS Homo sapiens 61404 R-HSA-174444 https://reactome.org/PathwayBrowser/#/R-HSA-174444 Formation of C-strand Okazaki fragments TAS Homo sapiens 61404 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 61404 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 61404 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 61404 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 61404 R-HSA-5358579 https://reactome.org/PathwayBrowser/#/R-HSA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap TAS Homo sapiens 61404 R-HSA-68950 https://reactome.org/PathwayBrowser/#/R-HSA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin TAS Homo sapiens 61404 R-HSA-8866405 https://reactome.org/PathwayBrowser/#/R-HSA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 61404 R-HSA-9710480 https://reactome.org/PathwayBrowser/#/R-HSA-9710480 Decitabine triphosphate incorporates into DNA TAS Homo sapiens 61404 R-MMU-110317 https://reactome.org/PathwayBrowser/#/R-MMU-110317 Insertion of correct bases opposite the lesion by POLH IEA Mus musculus 61404 R-MMU-111215 https://reactome.org/PathwayBrowser/#/R-MMU-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Mus musculus 61404 R-MMU-111742 https://reactome.org/PathwayBrowser/#/R-MMU-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 61404 R-MMU-111751 https://reactome.org/PathwayBrowser/#/R-MMU-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 61404 R-MMU-111804 https://reactome.org/PathwayBrowser/#/R-MMU-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 61404 R-MMU-163090 https://reactome.org/PathwayBrowser/#/R-MMU-163090 Elongation Of The Telomeric Chromosome End IEA Mus musculus 61404 R-MMU-164617 https://reactome.org/PathwayBrowser/#/R-MMU-164617 Elongation of Extended Telomeric Chromosome End IEA Mus musculus 61404 R-MMU-174427 https://reactome.org/PathwayBrowser/#/R-MMU-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Mus musculus 61404 R-MMU-174444 https://reactome.org/PathwayBrowser/#/R-MMU-174444 Formation of C-strand Okazaki fragments IEA Mus musculus 61404 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 61404 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 61404 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 61404 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 61404 R-MMU-5358579 https://reactome.org/PathwayBrowser/#/R-MMU-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Mus musculus 61404 R-MMU-68950 https://reactome.org/PathwayBrowser/#/R-MMU-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Mus musculus 61404 R-MMU-8866405 https://reactome.org/PathwayBrowser/#/R-MMU-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 61404 R-PFA-110317 https://reactome.org/PathwayBrowser/#/R-PFA-110317 Insertion of correct bases opposite the lesion by POLH IEA Plasmodium falciparum 61404 R-PFA-111215 https://reactome.org/PathwayBrowser/#/R-PFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Plasmodium falciparum 61404 R-PFA-111742 https://reactome.org/PathwayBrowser/#/R-PFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 61404 R-PFA-111751 https://reactome.org/PathwayBrowser/#/R-PFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 61404 R-PFA-111804 https://reactome.org/PathwayBrowser/#/R-PFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 61404 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 61404 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 61404 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 61404 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 61404 R-PFA-68950 https://reactome.org/PathwayBrowser/#/R-PFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Plasmodium falciparum 61404 R-PFA-8866405 https://reactome.org/PathwayBrowser/#/R-PFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 61404 R-RNO-110317 https://reactome.org/PathwayBrowser/#/R-RNO-110317 Insertion of correct bases opposite the lesion by POLH IEA Rattus norvegicus 61404 R-RNO-111215 https://reactome.org/PathwayBrowser/#/R-RNO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Rattus norvegicus 61404 R-RNO-111742 https://reactome.org/PathwayBrowser/#/R-RNO-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 61404 R-RNO-111751 https://reactome.org/PathwayBrowser/#/R-RNO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 61404 R-RNO-111804 https://reactome.org/PathwayBrowser/#/R-RNO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 61404 R-RNO-163090 https://reactome.org/PathwayBrowser/#/R-RNO-163090 Elongation Of The Telomeric Chromosome End IEA Rattus norvegicus 61404 R-RNO-164617 https://reactome.org/PathwayBrowser/#/R-RNO-164617 Elongation of Extended Telomeric Chromosome End IEA Rattus norvegicus 61404 R-RNO-174427 https://reactome.org/PathwayBrowser/#/R-RNO-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Rattus norvegicus 61404 R-RNO-174444 https://reactome.org/PathwayBrowser/#/R-RNO-174444 Formation of C-strand Okazaki fragments IEA Rattus norvegicus 61404 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 61404 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 61404 R-RNO-5358579 https://reactome.org/PathwayBrowser/#/R-RNO-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Rattus norvegicus 61404 R-RNO-68950 https://reactome.org/PathwayBrowser/#/R-RNO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Rattus norvegicus 61404 R-RNO-8866405 https://reactome.org/PathwayBrowser/#/R-RNO-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 61404 R-SCE-110317 https://reactome.org/PathwayBrowser/#/R-SCE-110317 Insertion of correct bases opposite the lesion by POLH IEA Saccharomyces cerevisiae 61404 R-SCE-111215 https://reactome.org/PathwayBrowser/#/R-SCE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Saccharomyces cerevisiae 61404 R-SCE-111751 https://reactome.org/PathwayBrowser/#/R-SCE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 61404 R-SCE-111804 https://reactome.org/PathwayBrowser/#/R-SCE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 61404 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 61404 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 61404 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 61404 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 61404 R-SCE-68950 https://reactome.org/PathwayBrowser/#/R-SCE-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Saccharomyces cerevisiae 61404 R-SPO-110317 https://reactome.org/PathwayBrowser/#/R-SPO-110317 Insertion of correct bases opposite the lesion by POLH IEA Schizosaccharomyces pombe 61404 R-SPO-111215 https://reactome.org/PathwayBrowser/#/R-SPO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Schizosaccharomyces pombe 61404 R-SPO-111751 https://reactome.org/PathwayBrowser/#/R-SPO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 61404 R-SPO-111804 https://reactome.org/PathwayBrowser/#/R-SPO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 61404 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 61404 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 61404 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 61404 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 61404 R-SPO-5358579 https://reactome.org/PathwayBrowser/#/R-SPO-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Schizosaccharomyces pombe 61404 R-SPO-68950 https://reactome.org/PathwayBrowser/#/R-SPO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Schizosaccharomyces pombe 61404 R-SSC-110317 https://reactome.org/PathwayBrowser/#/R-SSC-110317 Insertion of correct bases opposite the lesion by POLH IEA Sus scrofa 61404 R-SSC-111215 https://reactome.org/PathwayBrowser/#/R-SSC-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Sus scrofa 61404 R-SSC-111742 https://reactome.org/PathwayBrowser/#/R-SSC-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 61404 R-SSC-111751 https://reactome.org/PathwayBrowser/#/R-SSC-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 61404 R-SSC-111804 https://reactome.org/PathwayBrowser/#/R-SSC-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 61404 R-SSC-163090 https://reactome.org/PathwayBrowser/#/R-SSC-163090 Elongation Of The Telomeric Chromosome End IEA Sus scrofa 61404 R-SSC-164617 https://reactome.org/PathwayBrowser/#/R-SSC-164617 Elongation of Extended Telomeric Chromosome End IEA Sus scrofa 61404 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa 61404 R-SSC-174444 https://reactome.org/PathwayBrowser/#/R-SSC-174444 Formation of C-strand Okazaki fragments IEA Sus scrofa 61404 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 61404 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 61404 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 61404 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 61404 R-SSC-5358579 https://reactome.org/PathwayBrowser/#/R-SSC-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Sus scrofa 61404 R-SSC-68950 https://reactome.org/PathwayBrowser/#/R-SSC-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Sus scrofa 61404 R-SSC-8866405 https://reactome.org/PathwayBrowser/#/R-SSC-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 61404 R-XTR-110317 https://reactome.org/PathwayBrowser/#/R-XTR-110317 Insertion of correct bases opposite the lesion by POLH IEA Xenopus tropicalis 61404 R-XTR-111215 https://reactome.org/PathwayBrowser/#/R-XTR-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Xenopus tropicalis 61404 R-XTR-111742 https://reactome.org/PathwayBrowser/#/R-XTR-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 61404 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 61404 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 61404 R-XTR-8866405 https://reactome.org/PathwayBrowser/#/R-XTR-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 61429 R-BTA-163090 https://reactome.org/PathwayBrowser/#/R-BTA-163090 Elongation Of The Telomeric Chromosome End IEA Bos taurus 61429 R-BTA-164617 https://reactome.org/PathwayBrowser/#/R-BTA-164617 Elongation of Extended Telomeric Chromosome End IEA Bos taurus 61429 R-BTA-174427 https://reactome.org/PathwayBrowser/#/R-BTA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Bos taurus 61429 R-BTA-174444 https://reactome.org/PathwayBrowser/#/R-BTA-174444 Formation of C-strand Okazaki fragments IEA Bos taurus 61429 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 61429 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 61429 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 61429 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 61429 R-BTA-5358579 https://reactome.org/PathwayBrowser/#/R-BTA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Bos taurus 61429 R-BTA-68950 https://reactome.org/PathwayBrowser/#/R-BTA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Bos taurus 61429 R-BTA-8866601 https://reactome.org/PathwayBrowser/#/R-BTA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Bos taurus 61429 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 61429 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 61429 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 61429 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 61429 R-CEL-68950 https://reactome.org/PathwayBrowser/#/R-CEL-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Caenorhabditis elegans 61429 R-CEL-8866601 https://reactome.org/PathwayBrowser/#/R-CEL-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Caenorhabditis elegans 61429 R-CFA-163090 https://reactome.org/PathwayBrowser/#/R-CFA-163090 Elongation Of The Telomeric Chromosome End IEA Canis familiaris 61429 R-CFA-164617 https://reactome.org/PathwayBrowser/#/R-CFA-164617 Elongation of Extended Telomeric Chromosome End IEA Canis familiaris 61429 R-CFA-174427 https://reactome.org/PathwayBrowser/#/R-CFA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Canis familiaris 61429 R-CFA-174444 https://reactome.org/PathwayBrowser/#/R-CFA-174444 Formation of C-strand Okazaki fragments IEA Canis familiaris 61429 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 61429 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 61429 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 61429 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 61429 R-CFA-5358579 https://reactome.org/PathwayBrowser/#/R-CFA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Canis familiaris 61429 R-CFA-68950 https://reactome.org/PathwayBrowser/#/R-CFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Canis familiaris 61429 R-CFA-8866601 https://reactome.org/PathwayBrowser/#/R-CFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Canis familiaris 61429 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 61429 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 61429 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 61429 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 61429 R-DDI-68950 https://reactome.org/PathwayBrowser/#/R-DDI-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Dictyostelium discoideum 61429 R-DDI-8866601 https://reactome.org/PathwayBrowser/#/R-DDI-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Dictyostelium discoideum 61429 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 61429 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 61429 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 61429 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 61429 R-DME-68950 https://reactome.org/PathwayBrowser/#/R-DME-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Drosophila melanogaster 61429 R-DME-8866601 https://reactome.org/PathwayBrowser/#/R-DME-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Drosophila melanogaster 61429 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 61429 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 61429 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 61429 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 61429 R-DRE-8866601 https://reactome.org/PathwayBrowser/#/R-DRE-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Danio rerio 61429 R-GGA-163090 https://reactome.org/PathwayBrowser/#/R-GGA-163090 Elongation Of The Telomeric Chromosome End IEA Gallus gallus 61429 R-GGA-164617 https://reactome.org/PathwayBrowser/#/R-GGA-164617 Elongation of Extended Telomeric Chromosome End IEA Gallus gallus 61429 R-GGA-174427 https://reactome.org/PathwayBrowser/#/R-GGA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Gallus gallus 61429 R-GGA-417122 https://reactome.org/PathwayBrowser/#/R-GGA-417122 Elongation and translocation of the telomeric chromosome end IEA Gallus gallus 61429 R-GGA-417127 https://reactome.org/PathwayBrowser/#/R-GGA-417127 Elongation and translocation of the extended telomeric chromosome end IEA Gallus gallus 61429 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 61429 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 61429 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 61429 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 61429 R-GGA-68950 https://reactome.org/PathwayBrowser/#/R-GGA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Gallus gallus 61429 R-GGA-8866601 https://reactome.org/PathwayBrowser/#/R-GGA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Gallus gallus 61429 R-HSA-163090 https://reactome.org/PathwayBrowser/#/R-HSA-163090 Elongation Of The Telomeric Chromosome End TAS Homo sapiens 61429 R-HSA-164617 https://reactome.org/PathwayBrowser/#/R-HSA-164617 Elongation of Extended Telomeric Chromosome End TAS Homo sapiens 61429 R-HSA-174427 https://reactome.org/PathwayBrowser/#/R-HSA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere TAS Homo sapiens 61429 R-HSA-174444 https://reactome.org/PathwayBrowser/#/R-HSA-174444 Formation of C-strand Okazaki fragments TAS Homo sapiens 61429 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 61429 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 61429 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 61429 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 61429 R-HSA-5358579 https://reactome.org/PathwayBrowser/#/R-HSA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap TAS Homo sapiens 61429 R-HSA-68950 https://reactome.org/PathwayBrowser/#/R-HSA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin TAS Homo sapiens 61429 R-HSA-8866601 https://reactome.org/PathwayBrowser/#/R-HSA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate TAS Homo sapiens 61429 R-HSA-9710480 https://reactome.org/PathwayBrowser/#/R-HSA-9710480 Decitabine triphosphate incorporates into DNA TAS Homo sapiens 61429 R-MMU-163090 https://reactome.org/PathwayBrowser/#/R-MMU-163090 Elongation Of The Telomeric Chromosome End IEA Mus musculus 61429 R-MMU-164617 https://reactome.org/PathwayBrowser/#/R-MMU-164617 Elongation of Extended Telomeric Chromosome End IEA Mus musculus 61429 R-MMU-174427 https://reactome.org/PathwayBrowser/#/R-MMU-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Mus musculus 61429 R-MMU-174444 https://reactome.org/PathwayBrowser/#/R-MMU-174444 Formation of C-strand Okazaki fragments IEA Mus musculus 61429 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 61429 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 61429 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 61429 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 61429 R-MMU-5358579 https://reactome.org/PathwayBrowser/#/R-MMU-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Mus musculus 61429 R-MMU-68950 https://reactome.org/PathwayBrowser/#/R-MMU-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Mus musculus 61429 R-MMU-8866601 https://reactome.org/PathwayBrowser/#/R-MMU-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Mus musculus 61429 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 61429 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 61429 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 61429 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 61429 R-PFA-68950 https://reactome.org/PathwayBrowser/#/R-PFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Plasmodium falciparum 61429 R-PFA-8866601 https://reactome.org/PathwayBrowser/#/R-PFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Plasmodium falciparum 61429 R-RNO-163090 https://reactome.org/PathwayBrowser/#/R-RNO-163090 Elongation Of The Telomeric Chromosome End IEA Rattus norvegicus 61429 R-RNO-164617 https://reactome.org/PathwayBrowser/#/R-RNO-164617 Elongation of Extended Telomeric Chromosome End IEA Rattus norvegicus 61429 R-RNO-174427 https://reactome.org/PathwayBrowser/#/R-RNO-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Rattus norvegicus 61429 R-RNO-174444 https://reactome.org/PathwayBrowser/#/R-RNO-174444 Formation of C-strand Okazaki fragments IEA Rattus norvegicus 61429 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 61429 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 61429 R-RNO-5358579 https://reactome.org/PathwayBrowser/#/R-RNO-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Rattus norvegicus 61429 R-RNO-68950 https://reactome.org/PathwayBrowser/#/R-RNO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Rattus norvegicus 61429 R-RNO-8866601 https://reactome.org/PathwayBrowser/#/R-RNO-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Rattus norvegicus 61429 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 61429 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 61429 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 61429 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 61429 R-SCE-68950 https://reactome.org/PathwayBrowser/#/R-SCE-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Saccharomyces cerevisiae 61429 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 61429 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 61429 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 61429 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 61429 R-SPO-5358579 https://reactome.org/PathwayBrowser/#/R-SPO-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Schizosaccharomyces pombe 61429 R-SPO-68950 https://reactome.org/PathwayBrowser/#/R-SPO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Schizosaccharomyces pombe 61429 R-SSC-163090 https://reactome.org/PathwayBrowser/#/R-SSC-163090 Elongation Of The Telomeric Chromosome End IEA Sus scrofa 61429 R-SSC-164617 https://reactome.org/PathwayBrowser/#/R-SSC-164617 Elongation of Extended Telomeric Chromosome End IEA Sus scrofa 61429 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa 61429 R-SSC-174444 https://reactome.org/PathwayBrowser/#/R-SSC-174444 Formation of C-strand Okazaki fragments IEA Sus scrofa 61429 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 61429 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 61429 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 61429 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 61429 R-SSC-5358579 https://reactome.org/PathwayBrowser/#/R-SSC-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Sus scrofa 61429 R-SSC-68950 https://reactome.org/PathwayBrowser/#/R-SSC-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Sus scrofa 61429 R-SSC-8866601 https://reactome.org/PathwayBrowser/#/R-SSC-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Sus scrofa 61429 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 61429 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 61429 R-XTR-8866601 https://reactome.org/PathwayBrowser/#/R-XTR-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Xenopus tropicalis 61472 R-SCE-2164813 https://reactome.org/PathwayBrowser/#/R-SCE-2164813 HMPhOH is hydroxylated to MDMQ6H2 by HMPhOH monooxygenase TAS Saccharomyces cerevisiae 61481 R-BTA-110308 https://reactome.org/PathwayBrowser/#/R-BTA-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Bos taurus 61481 R-BTA-163090 https://reactome.org/PathwayBrowser/#/R-BTA-163090 Elongation Of The Telomeric Chromosome End IEA Bos taurus 61481 R-BTA-164617 https://reactome.org/PathwayBrowser/#/R-BTA-164617 Elongation of Extended Telomeric Chromosome End IEA Bos taurus 61481 R-BTA-174427 https://reactome.org/PathwayBrowser/#/R-BTA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Bos taurus 61481 R-BTA-174444 https://reactome.org/PathwayBrowser/#/R-BTA-174444 Formation of C-strand Okazaki fragments IEA Bos taurus 61481 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 61481 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 61481 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 61481 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 61481 R-BTA-5358579 https://reactome.org/PathwayBrowser/#/R-BTA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Bos taurus 61481 R-BTA-68950 https://reactome.org/PathwayBrowser/#/R-BTA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Bos taurus 61481 R-CEL-110308 https://reactome.org/PathwayBrowser/#/R-CEL-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Caenorhabditis elegans 61481 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 61481 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 61481 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 61481 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 61481 R-CEL-68950 https://reactome.org/PathwayBrowser/#/R-CEL-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Caenorhabditis elegans 61481 R-CFA-110308 https://reactome.org/PathwayBrowser/#/R-CFA-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Canis familiaris 61481 R-CFA-163090 https://reactome.org/PathwayBrowser/#/R-CFA-163090 Elongation Of The Telomeric Chromosome End IEA Canis familiaris 61481 R-CFA-164617 https://reactome.org/PathwayBrowser/#/R-CFA-164617 Elongation of Extended Telomeric Chromosome End IEA Canis familiaris 61481 R-CFA-174427 https://reactome.org/PathwayBrowser/#/R-CFA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Canis familiaris 61481 R-CFA-174444 https://reactome.org/PathwayBrowser/#/R-CFA-174444 Formation of C-strand Okazaki fragments IEA Canis familiaris 61481 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 61481 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 61481 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 61481 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 61481 R-CFA-5358579 https://reactome.org/PathwayBrowser/#/R-CFA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Canis familiaris 61481 R-CFA-68950 https://reactome.org/PathwayBrowser/#/R-CFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Canis familiaris 61481 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 61481 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 61481 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 61481 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 61481 R-DDI-68950 https://reactome.org/PathwayBrowser/#/R-DDI-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Dictyostelium discoideum 61481 R-DME-110308 https://reactome.org/PathwayBrowser/#/R-DME-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Drosophila melanogaster 61481 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 61481 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 61481 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 61481 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 61481 R-DME-68950 https://reactome.org/PathwayBrowser/#/R-DME-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Drosophila melanogaster 61481 R-DRE-110308 https://reactome.org/PathwayBrowser/#/R-DRE-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Danio rerio 61481 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 61481 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 61481 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 61481 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 61481 R-GGA-110308 https://reactome.org/PathwayBrowser/#/R-GGA-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Gallus gallus 61481 R-GGA-163090 https://reactome.org/PathwayBrowser/#/R-GGA-163090 Elongation Of The Telomeric Chromosome End IEA Gallus gallus 61481 R-GGA-164617 https://reactome.org/PathwayBrowser/#/R-GGA-164617 Elongation of Extended Telomeric Chromosome End IEA Gallus gallus 61481 R-GGA-174427 https://reactome.org/PathwayBrowser/#/R-GGA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Gallus gallus 61481 R-GGA-417122 https://reactome.org/PathwayBrowser/#/R-GGA-417122 Elongation and translocation of the telomeric chromosome end IEA Gallus gallus 61481 R-GGA-417127 https://reactome.org/PathwayBrowser/#/R-GGA-417127 Elongation and translocation of the extended telomeric chromosome end IEA Gallus gallus 61481 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 61481 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 61481 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 61481 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 61481 R-GGA-68950 https://reactome.org/PathwayBrowser/#/R-GGA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Gallus gallus 61481 R-HSA-110308 https://reactome.org/PathwayBrowser/#/R-HSA-110308 REV1 inserts dCMP opposite to AP sites in DNA TAS Homo sapiens 61481 R-HSA-163090 https://reactome.org/PathwayBrowser/#/R-HSA-163090 Elongation Of The Telomeric Chromosome End TAS Homo sapiens 61481 R-HSA-164617 https://reactome.org/PathwayBrowser/#/R-HSA-164617 Elongation of Extended Telomeric Chromosome End TAS Homo sapiens 61481 R-HSA-174427 https://reactome.org/PathwayBrowser/#/R-HSA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere TAS Homo sapiens 61481 R-HSA-174444 https://reactome.org/PathwayBrowser/#/R-HSA-174444 Formation of C-strand Okazaki fragments TAS Homo sapiens 61481 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 61481 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 61481 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 61481 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 61481 R-HSA-5358579 https://reactome.org/PathwayBrowser/#/R-HSA-5358579 DNA polymerase delta polymerizes DNA across single stranded gap TAS Homo sapiens 61481 R-HSA-68950 https://reactome.org/PathwayBrowser/#/R-HSA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin TAS Homo sapiens 61481 R-HSA-9710480 https://reactome.org/PathwayBrowser/#/R-HSA-9710480 Decitabine triphosphate incorporates into DNA TAS Homo sapiens 61481 R-MMU-110308 https://reactome.org/PathwayBrowser/#/R-MMU-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Mus musculus 61481 R-MMU-163090 https://reactome.org/PathwayBrowser/#/R-MMU-163090 Elongation Of The Telomeric Chromosome End IEA Mus musculus 61481 R-MMU-164617 https://reactome.org/PathwayBrowser/#/R-MMU-164617 Elongation of Extended Telomeric Chromosome End IEA Mus musculus 61481 R-MMU-174427 https://reactome.org/PathwayBrowser/#/R-MMU-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Mus musculus 61481 R-MMU-174444 https://reactome.org/PathwayBrowser/#/R-MMU-174444 Formation of C-strand Okazaki fragments IEA Mus musculus 61481 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 61481 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 61481 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 61481 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 61481 R-MMU-5358579 https://reactome.org/PathwayBrowser/#/R-MMU-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Mus musculus 61481 R-MMU-68950 https://reactome.org/PathwayBrowser/#/R-MMU-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Mus musculus 61481 R-PFA-110308 https://reactome.org/PathwayBrowser/#/R-PFA-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Plasmodium falciparum 61481 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 61481 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 61481 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 61481 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 61481 R-PFA-68950 https://reactome.org/PathwayBrowser/#/R-PFA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Plasmodium falciparum 61481 R-RNO-110308 https://reactome.org/PathwayBrowser/#/R-RNO-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Rattus norvegicus 61481 R-RNO-163090 https://reactome.org/PathwayBrowser/#/R-RNO-163090 Elongation Of The Telomeric Chromosome End IEA Rattus norvegicus 61481 R-RNO-164617 https://reactome.org/PathwayBrowser/#/R-RNO-164617 Elongation of Extended Telomeric Chromosome End IEA Rattus norvegicus 61481 R-RNO-174427 https://reactome.org/PathwayBrowser/#/R-RNO-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Rattus norvegicus 61481 R-RNO-174444 https://reactome.org/PathwayBrowser/#/R-RNO-174444 Formation of C-strand Okazaki fragments IEA Rattus norvegicus 61481 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 61481 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 61481 R-RNO-5358579 https://reactome.org/PathwayBrowser/#/R-RNO-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Rattus norvegicus 61481 R-RNO-68950 https://reactome.org/PathwayBrowser/#/R-RNO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Rattus norvegicus 61481 R-SCE-110308 https://reactome.org/PathwayBrowser/#/R-SCE-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Saccharomyces cerevisiae 61481 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 61481 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 61481 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 61481 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 61481 R-SCE-68950 https://reactome.org/PathwayBrowser/#/R-SCE-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Saccharomyces cerevisiae 61481 R-SPO-110308 https://reactome.org/PathwayBrowser/#/R-SPO-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Schizosaccharomyces pombe 61481 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 61481 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 61481 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 61481 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 61481 R-SPO-5358579 https://reactome.org/PathwayBrowser/#/R-SPO-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Schizosaccharomyces pombe 61481 R-SPO-68950 https://reactome.org/PathwayBrowser/#/R-SPO-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Schizosaccharomyces pombe 61481 R-SSC-110308 https://reactome.org/PathwayBrowser/#/R-SSC-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Sus scrofa 61481 R-SSC-163090 https://reactome.org/PathwayBrowser/#/R-SSC-163090 Elongation Of The Telomeric Chromosome End IEA Sus scrofa 61481 R-SSC-164617 https://reactome.org/PathwayBrowser/#/R-SSC-164617 Elongation of Extended Telomeric Chromosome End IEA Sus scrofa 61481 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa 61481 R-SSC-174444 https://reactome.org/PathwayBrowser/#/R-SSC-174444 Formation of C-strand Okazaki fragments IEA Sus scrofa 61481 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 61481 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 61481 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 61481 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 61481 R-SSC-5358579 https://reactome.org/PathwayBrowser/#/R-SSC-5358579 DNA polymerase delta polymerizes DNA across single stranded gap IEA Sus scrofa 61481 R-SSC-68950 https://reactome.org/PathwayBrowser/#/R-SSC-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Sus scrofa 61481 R-XTR-110308 https://reactome.org/PathwayBrowser/#/R-XTR-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Xenopus tropicalis 61481 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 61481 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 61526 R-BTA-77299 https://reactome.org/PathwayBrowser/#/R-BTA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Bos taurus 61526 R-BTA-77301 https://reactome.org/PathwayBrowser/#/R-BTA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Bos taurus 61526 R-CEL-77299 https://reactome.org/PathwayBrowser/#/R-CEL-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 61526 R-CEL-77301 https://reactome.org/PathwayBrowser/#/R-CEL-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Caenorhabditis elegans 61526 R-CFA-77299 https://reactome.org/PathwayBrowser/#/R-CFA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Canis familiaris 61526 R-CFA-77301 https://reactome.org/PathwayBrowser/#/R-CFA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Canis familiaris 61526 R-DME-77299 https://reactome.org/PathwayBrowser/#/R-DME-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 61526 R-DME-77301 https://reactome.org/PathwayBrowser/#/R-DME-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Drosophila melanogaster 61526 R-DRE-77299 https://reactome.org/PathwayBrowser/#/R-DRE-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Danio rerio 61526 R-DRE-77301 https://reactome.org/PathwayBrowser/#/R-DRE-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Danio rerio 61526 R-GGA-77301 https://reactome.org/PathwayBrowser/#/R-GGA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Gallus gallus 61526 R-HSA-77299 https://reactome.org/PathwayBrowser/#/R-HSA-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 TAS Homo sapiens 61526 R-HSA-77301 https://reactome.org/PathwayBrowser/#/R-HSA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA TAS Homo sapiens 61526 R-MMU-77299 https://reactome.org/PathwayBrowser/#/R-MMU-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Mus musculus 61526 R-MMU-77301 https://reactome.org/PathwayBrowser/#/R-MMU-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Mus musculus 61526 R-RNO-77299 https://reactome.org/PathwayBrowser/#/R-RNO-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 61526 R-RNO-77301 https://reactome.org/PathwayBrowser/#/R-RNO-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Rattus norvegicus 61526 R-SSC-77299 https://reactome.org/PathwayBrowser/#/R-SSC-77299 palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2 IEA Sus scrofa 61526 R-SSC-77301 https://reactome.org/PathwayBrowser/#/R-SSC-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Sus scrofa 61526 R-XTR-77301 https://reactome.org/PathwayBrowser/#/R-XTR-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Xenopus tropicalis 61555 R-BTA-482619 https://reactome.org/PathwayBrowser/#/R-BTA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Bos taurus 61555 R-BTA-482621 https://reactome.org/PathwayBrowser/#/R-BTA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Bos taurus 61555 R-BTA-482804 https://reactome.org/PathwayBrowser/#/R-BTA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Bos taurus 61555 R-BTA-482812 https://reactome.org/PathwayBrowser/#/R-BTA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Bos taurus 61555 R-BTA-73666 https://reactome.org/PathwayBrowser/#/R-BTA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Bos taurus 61555 R-CEL-482619 https://reactome.org/PathwayBrowser/#/R-CEL-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Caenorhabditis elegans 61555 R-CEL-482621 https://reactome.org/PathwayBrowser/#/R-CEL-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Caenorhabditis elegans 61555 R-CEL-482804 https://reactome.org/PathwayBrowser/#/R-CEL-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Caenorhabditis elegans 61555 R-CEL-482812 https://reactome.org/PathwayBrowser/#/R-CEL-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Caenorhabditis elegans 61555 R-CEL-73666 https://reactome.org/PathwayBrowser/#/R-CEL-73666 dUTP + H2O => dUMP + pyrophosphate IEA Caenorhabditis elegans 61555 R-CFA-482619 https://reactome.org/PathwayBrowser/#/R-CFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Canis familiaris 61555 R-CFA-482621 https://reactome.org/PathwayBrowser/#/R-CFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Canis familiaris 61555 R-CFA-482804 https://reactome.org/PathwayBrowser/#/R-CFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Canis familiaris 61555 R-CFA-482812 https://reactome.org/PathwayBrowser/#/R-CFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Canis familiaris 61555 R-CFA-73666 https://reactome.org/PathwayBrowser/#/R-CFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Canis familiaris 61555 R-DDI-482619 https://reactome.org/PathwayBrowser/#/R-DDI-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Dictyostelium discoideum 61555 R-DDI-482621 https://reactome.org/PathwayBrowser/#/R-DDI-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Dictyostelium discoideum 61555 R-DDI-482804 https://reactome.org/PathwayBrowser/#/R-DDI-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Dictyostelium discoideum 61555 R-DDI-482812 https://reactome.org/PathwayBrowser/#/R-DDI-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Dictyostelium discoideum 61555 R-DDI-73666 https://reactome.org/PathwayBrowser/#/R-DDI-73666 dUTP + H2O => dUMP + pyrophosphate IEA Dictyostelium discoideum 61555 R-DME-482619 https://reactome.org/PathwayBrowser/#/R-DME-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Drosophila melanogaster 61555 R-DME-482621 https://reactome.org/PathwayBrowser/#/R-DME-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Drosophila melanogaster 61555 R-DME-482804 https://reactome.org/PathwayBrowser/#/R-DME-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Drosophila melanogaster 61555 R-DME-482812 https://reactome.org/PathwayBrowser/#/R-DME-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Drosophila melanogaster 61555 R-DME-73666 https://reactome.org/PathwayBrowser/#/R-DME-73666 dUTP + H2O => dUMP + pyrophosphate IEA Drosophila melanogaster 61555 R-DRE-482619 https://reactome.org/PathwayBrowser/#/R-DRE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Danio rerio 61555 R-DRE-482621 https://reactome.org/PathwayBrowser/#/R-DRE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Danio rerio 61555 R-DRE-482804 https://reactome.org/PathwayBrowser/#/R-DRE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Danio rerio 61555 R-DRE-482812 https://reactome.org/PathwayBrowser/#/R-DRE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Danio rerio 61555 R-DRE-73666 https://reactome.org/PathwayBrowser/#/R-DRE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Danio rerio 61555 R-GGA-482619 https://reactome.org/PathwayBrowser/#/R-GGA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Gallus gallus 61555 R-GGA-482621 https://reactome.org/PathwayBrowser/#/R-GGA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Gallus gallus 61555 R-GGA-482804 https://reactome.org/PathwayBrowser/#/R-GGA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Gallus gallus 61555 R-GGA-482812 https://reactome.org/PathwayBrowser/#/R-GGA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Gallus gallus 61555 R-GGA-73666 https://reactome.org/PathwayBrowser/#/R-GGA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Gallus gallus 61555 R-HSA-482619 https://reactome.org/PathwayBrowser/#/R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) TAS Homo sapiens 61555 R-HSA-482621 https://reactome.org/PathwayBrowser/#/R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) TAS Homo sapiens 61555 R-HSA-482804 https://reactome.org/PathwayBrowser/#/R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) TAS Homo sapiens 61555 R-HSA-482812 https://reactome.org/PathwayBrowser/#/R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) TAS Homo sapiens 61555 R-HSA-73666 https://reactome.org/PathwayBrowser/#/R-HSA-73666 dUTP + H2O => dUMP + pyrophosphate TAS Homo sapiens 61555 R-MMU-482619 https://reactome.org/PathwayBrowser/#/R-MMU-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Mus musculus 61555 R-MMU-482621 https://reactome.org/PathwayBrowser/#/R-MMU-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Mus musculus 61555 R-MMU-482804 https://reactome.org/PathwayBrowser/#/R-MMU-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Mus musculus 61555 R-MMU-482812 https://reactome.org/PathwayBrowser/#/R-MMU-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Mus musculus 61555 R-MMU-73666 https://reactome.org/PathwayBrowser/#/R-MMU-73666 dUTP + H2O => dUMP + pyrophosphate IEA Mus musculus 61555 R-PFA-482619 https://reactome.org/PathwayBrowser/#/R-PFA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Plasmodium falciparum 61555 R-PFA-482621 https://reactome.org/PathwayBrowser/#/R-PFA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Plasmodium falciparum 61555 R-PFA-482804 https://reactome.org/PathwayBrowser/#/R-PFA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Plasmodium falciparum 61555 R-PFA-482812 https://reactome.org/PathwayBrowser/#/R-PFA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Plasmodium falciparum 61555 R-PFA-73666 https://reactome.org/PathwayBrowser/#/R-PFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Plasmodium falciparum 61555 R-RNO-482619 https://reactome.org/PathwayBrowser/#/R-RNO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Rattus norvegicus 61555 R-RNO-482621 https://reactome.org/PathwayBrowser/#/R-RNO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Rattus norvegicus 61555 R-RNO-73666 https://reactome.org/PathwayBrowser/#/R-RNO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Rattus norvegicus 61555 R-SCE-482619 https://reactome.org/PathwayBrowser/#/R-SCE-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Saccharomyces cerevisiae 61555 R-SCE-482621 https://reactome.org/PathwayBrowser/#/R-SCE-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Saccharomyces cerevisiae 61555 R-SCE-482804 https://reactome.org/PathwayBrowser/#/R-SCE-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Saccharomyces cerevisiae 61555 R-SCE-482812 https://reactome.org/PathwayBrowser/#/R-SCE-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Saccharomyces cerevisiae 61555 R-SCE-73666 https://reactome.org/PathwayBrowser/#/R-SCE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Saccharomyces cerevisiae 61555 R-SPO-482619 https://reactome.org/PathwayBrowser/#/R-SPO-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Schizosaccharomyces pombe 61555 R-SPO-482621 https://reactome.org/PathwayBrowser/#/R-SPO-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Schizosaccharomyces pombe 61555 R-SPO-482804 https://reactome.org/PathwayBrowser/#/R-SPO-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Schizosaccharomyces pombe 61555 R-SPO-482812 https://reactome.org/PathwayBrowser/#/R-SPO-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Schizosaccharomyces pombe 61555 R-SPO-73666 https://reactome.org/PathwayBrowser/#/R-SPO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Schizosaccharomyces pombe 61555 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa 61555 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa 61555 R-SSC-482804 https://reactome.org/PathwayBrowser/#/R-SSC-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) IEA Sus scrofa 61555 R-SSC-482812 https://reactome.org/PathwayBrowser/#/R-SSC-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) IEA Sus scrofa 61555 R-SSC-73666 https://reactome.org/PathwayBrowser/#/R-SSC-73666 dUTP + H2O => dUMP + pyrophosphate IEA Sus scrofa 61555 R-XTR-482619 https://reactome.org/PathwayBrowser/#/R-XTR-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Xenopus tropicalis 61555 R-XTR-482621 https://reactome.org/PathwayBrowser/#/R-XTR-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Xenopus tropicalis 61555 R-XTR-73666 https://reactome.org/PathwayBrowser/#/R-XTR-73666 dUTP + H2O => dUMP + pyrophosphate IEA Xenopus tropicalis 61557 R-BTA-111264 https://reactome.org/PathwayBrowser/#/R-BTA-111264 Addition of nucleotides between position +11 and +30 IEA Bos taurus 61557 R-BTA-112385 https://reactome.org/PathwayBrowser/#/R-BTA-112385 Addition of nucleotides leads to transcript elongation IEA Bos taurus 61557 R-BTA-112392 https://reactome.org/PathwayBrowser/#/R-BTA-112392 Resumption of elongation after recovery from pausing IEA Bos taurus 61557 R-BTA-112395 https://reactome.org/PathwayBrowser/#/R-BTA-112395 Abortive termination of elongation after arrest IEA Bos taurus 61557 R-BTA-112396 https://reactome.org/PathwayBrowser/#/R-BTA-112396 Separation of elongating transcript from template IEA Bos taurus 61557 R-BTA-113402 https://reactome.org/PathwayBrowser/#/R-BTA-113402 Formation of DSIF:NELF:early elongation complex IEA Bos taurus 61557 R-BTA-113411 https://reactome.org/PathwayBrowser/#/R-BTA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Bos taurus 61557 R-BTA-113412 https://reactome.org/PathwayBrowser/#/R-BTA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Bos taurus 61557 R-BTA-113413 https://reactome.org/PathwayBrowser/#/R-BTA-113413 TFIIS-mediated recovery of elongation from arrest IEA Bos taurus 61557 R-BTA-113414 https://reactome.org/PathwayBrowser/#/R-BTA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Bos taurus 61557 R-BTA-174425 https://reactome.org/PathwayBrowser/#/R-BTA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Bos taurus 61557 R-BTA-6806877 https://reactome.org/PathwayBrowser/#/R-BTA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Bos taurus 61557 R-BTA-68913 https://reactome.org/PathwayBrowser/#/R-BTA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Bos taurus 61557 R-BTA-74986 https://reactome.org/PathwayBrowser/#/R-BTA-74986 Elongation of pre-rRNA transcript IEA Bos taurus 61557 R-BTA-75850 https://reactome.org/PathwayBrowser/#/R-BTA-75850 Addition of the third nucleotide on the nascent transcript IEA Bos taurus 61557 R-BTA-75861 https://reactome.org/PathwayBrowser/#/R-BTA-75861 NTP Binds Active Site of RNA Polymerase II IEA Bos taurus 61557 R-BTA-75866 https://reactome.org/PathwayBrowser/#/R-BTA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Bos taurus 61557 R-BTA-75869 https://reactome.org/PathwayBrowser/#/R-BTA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Bos taurus 61557 R-BTA-75873 https://reactome.org/PathwayBrowser/#/R-BTA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Bos taurus 61557 R-BTA-76576 https://reactome.org/PathwayBrowser/#/R-BTA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Bos taurus 61557 R-BTA-8850846 https://reactome.org/PathwayBrowser/#/R-BTA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Bos taurus 61557 R-BTA-8851110 https://reactome.org/PathwayBrowser/#/R-BTA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Bos taurus 61557 R-BTA-9613497 https://reactome.org/PathwayBrowser/#/R-BTA-9613497 Unwinding DNA for the nascent transcript IEA Bos taurus 61557 R-CEL-111264 https://reactome.org/PathwayBrowser/#/R-CEL-111264 Addition of nucleotides between position +11 and +30 IEA Caenorhabditis elegans 61557 R-CEL-112385 https://reactome.org/PathwayBrowser/#/R-CEL-112385 Addition of nucleotides leads to transcript elongation IEA Caenorhabditis elegans 61557 R-CEL-112392 https://reactome.org/PathwayBrowser/#/R-CEL-112392 Resumption of elongation after recovery from pausing IEA Caenorhabditis elegans 61557 R-CEL-112395 https://reactome.org/PathwayBrowser/#/R-CEL-112395 Abortive termination of elongation after arrest IEA Caenorhabditis elegans 61557 R-CEL-112396 https://reactome.org/PathwayBrowser/#/R-CEL-112396 Separation of elongating transcript from template IEA Caenorhabditis elegans 61557 R-CEL-113411 https://reactome.org/PathwayBrowser/#/R-CEL-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Caenorhabditis elegans 61557 R-CEL-113412 https://reactome.org/PathwayBrowser/#/R-CEL-113412 Pol II elongation complex moves on the template as transcript elongates IEA Caenorhabditis elegans 61557 R-CEL-113413 https://reactome.org/PathwayBrowser/#/R-CEL-113413 TFIIS-mediated recovery of elongation from arrest IEA Caenorhabditis elegans 61557 R-CEL-113414 https://reactome.org/PathwayBrowser/#/R-CEL-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Caenorhabditis elegans 61557 R-CEL-6806877 https://reactome.org/PathwayBrowser/#/R-CEL-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Caenorhabditis elegans 61557 R-CEL-68913 https://reactome.org/PathwayBrowser/#/R-CEL-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Caenorhabditis elegans 61557 R-CEL-74986 https://reactome.org/PathwayBrowser/#/R-CEL-74986 Elongation of pre-rRNA transcript IEA Caenorhabditis elegans 61557 R-CEL-75850 https://reactome.org/PathwayBrowser/#/R-CEL-75850 Addition of the third nucleotide on the nascent transcript IEA Caenorhabditis elegans 61557 R-CEL-75861 https://reactome.org/PathwayBrowser/#/R-CEL-75861 NTP Binds Active Site of RNA Polymerase II IEA Caenorhabditis elegans 61557 R-CEL-75866 https://reactome.org/PathwayBrowser/#/R-CEL-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Caenorhabditis elegans 61557 R-CEL-75869 https://reactome.org/PathwayBrowser/#/R-CEL-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Caenorhabditis elegans 61557 R-CEL-75873 https://reactome.org/PathwayBrowser/#/R-CEL-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Caenorhabditis elegans 61557 R-CEL-76576 https://reactome.org/PathwayBrowser/#/R-CEL-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Caenorhabditis elegans 61557 R-CEL-9613497 https://reactome.org/PathwayBrowser/#/R-CEL-9613497 Unwinding DNA for the nascent transcript IEA Caenorhabditis elegans 61557 R-CFA-111264 https://reactome.org/PathwayBrowser/#/R-CFA-111264 Addition of nucleotides between position +11 and +30 IEA Canis familiaris 61557 R-CFA-112385 https://reactome.org/PathwayBrowser/#/R-CFA-112385 Addition of nucleotides leads to transcript elongation IEA Canis familiaris 61557 R-CFA-112392 https://reactome.org/PathwayBrowser/#/R-CFA-112392 Resumption of elongation after recovery from pausing IEA Canis familiaris 61557 R-CFA-112395 https://reactome.org/PathwayBrowser/#/R-CFA-112395 Abortive termination of elongation after arrest IEA Canis familiaris 61557 R-CFA-112396 https://reactome.org/PathwayBrowser/#/R-CFA-112396 Separation of elongating transcript from template IEA Canis familiaris 61557 R-CFA-113402 https://reactome.org/PathwayBrowser/#/R-CFA-113402 Formation of DSIF:NELF:early elongation complex IEA Canis familiaris 61557 R-CFA-113411 https://reactome.org/PathwayBrowser/#/R-CFA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Canis familiaris 61557 R-CFA-113412 https://reactome.org/PathwayBrowser/#/R-CFA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Canis familiaris 61557 R-CFA-113413 https://reactome.org/PathwayBrowser/#/R-CFA-113413 TFIIS-mediated recovery of elongation from arrest IEA Canis familiaris 61557 R-CFA-113414 https://reactome.org/PathwayBrowser/#/R-CFA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Canis familiaris 61557 R-CFA-113429 https://reactome.org/PathwayBrowser/#/R-CFA-113429 Elongating transcript encounters a lesion in the template IEA Canis familiaris 61557 R-CFA-174425 https://reactome.org/PathwayBrowser/#/R-CFA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Canis familiaris 61557 R-CFA-6806877 https://reactome.org/PathwayBrowser/#/R-CFA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Canis familiaris 61557 R-CFA-68913 https://reactome.org/PathwayBrowser/#/R-CFA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Canis familiaris 61557 R-CFA-74986 https://reactome.org/PathwayBrowser/#/R-CFA-74986 Elongation of pre-rRNA transcript IEA Canis familiaris 61557 R-CFA-75850 https://reactome.org/PathwayBrowser/#/R-CFA-75850 Addition of the third nucleotide on the nascent transcript IEA Canis familiaris 61557 R-CFA-75861 https://reactome.org/PathwayBrowser/#/R-CFA-75861 NTP Binds Active Site of RNA Polymerase II IEA Canis familiaris 61557 R-CFA-75866 https://reactome.org/PathwayBrowser/#/R-CFA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Canis familiaris 61557 R-CFA-75869 https://reactome.org/PathwayBrowser/#/R-CFA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Canis familiaris 61557 R-CFA-75873 https://reactome.org/PathwayBrowser/#/R-CFA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Canis familiaris 61557 R-CFA-76576 https://reactome.org/PathwayBrowser/#/R-CFA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Canis familiaris 61557 R-CFA-8850846 https://reactome.org/PathwayBrowser/#/R-CFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Canis familiaris 61557 R-CFA-8851110 https://reactome.org/PathwayBrowser/#/R-CFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Canis familiaris 61557 R-CFA-9613497 https://reactome.org/PathwayBrowser/#/R-CFA-9613497 Unwinding DNA for the nascent transcript IEA Canis familiaris 61557 R-DDI-111264 https://reactome.org/PathwayBrowser/#/R-DDI-111264 Addition of nucleotides between position +11 and +30 IEA Dictyostelium discoideum 61557 R-DDI-6806877 https://reactome.org/PathwayBrowser/#/R-DDI-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Dictyostelium discoideum 61557 R-DDI-68913 https://reactome.org/PathwayBrowser/#/R-DDI-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Dictyostelium discoideum 61557 R-DDI-74986 https://reactome.org/PathwayBrowser/#/R-DDI-74986 Elongation of pre-rRNA transcript IEA Dictyostelium discoideum 61557 R-DDI-75850 https://reactome.org/PathwayBrowser/#/R-DDI-75850 Addition of the third nucleotide on the nascent transcript IEA Dictyostelium discoideum 61557 R-DDI-75861 https://reactome.org/PathwayBrowser/#/R-DDI-75861 NTP Binds Active Site of RNA Polymerase II IEA Dictyostelium discoideum 61557 R-DDI-75866 https://reactome.org/PathwayBrowser/#/R-DDI-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Dictyostelium discoideum 61557 R-DDI-75869 https://reactome.org/PathwayBrowser/#/R-DDI-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Dictyostelium discoideum 61557 R-DDI-75873 https://reactome.org/PathwayBrowser/#/R-DDI-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Dictyostelium discoideum 61557 R-DDI-76576 https://reactome.org/PathwayBrowser/#/R-DDI-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Dictyostelium discoideum 61557 R-DDI-9613497 https://reactome.org/PathwayBrowser/#/R-DDI-9613497 Unwinding DNA for the nascent transcript IEA Dictyostelium discoideum 61557 R-DME-111264 https://reactome.org/PathwayBrowser/#/R-DME-111264 Addition of nucleotides between position +11 and +30 IEA Drosophila melanogaster 61557 R-DME-112385 https://reactome.org/PathwayBrowser/#/R-DME-112385 Addition of nucleotides leads to transcript elongation IEA Drosophila melanogaster 61557 R-DME-112392 https://reactome.org/PathwayBrowser/#/R-DME-112392 Resumption of elongation after recovery from pausing IEA Drosophila melanogaster 61557 R-DME-112395 https://reactome.org/PathwayBrowser/#/R-DME-112395 Abortive termination of elongation after arrest IEA Drosophila melanogaster 61557 R-DME-112396 https://reactome.org/PathwayBrowser/#/R-DME-112396 Separation of elongating transcript from template IEA Drosophila melanogaster 61557 R-DME-113402 https://reactome.org/PathwayBrowser/#/R-DME-113402 Formation of DSIF:NELF:early elongation complex IEA Drosophila melanogaster 61557 R-DME-113411 https://reactome.org/PathwayBrowser/#/R-DME-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Drosophila melanogaster 61557 R-DME-113412 https://reactome.org/PathwayBrowser/#/R-DME-113412 Pol II elongation complex moves on the template as transcript elongates IEA Drosophila melanogaster 61557 R-DME-113413 https://reactome.org/PathwayBrowser/#/R-DME-113413 TFIIS-mediated recovery of elongation from arrest IEA Drosophila melanogaster 61557 R-DME-113414 https://reactome.org/PathwayBrowser/#/R-DME-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Drosophila melanogaster 61557 R-DME-6806877 https://reactome.org/PathwayBrowser/#/R-DME-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Drosophila melanogaster 61557 R-DME-68913 https://reactome.org/PathwayBrowser/#/R-DME-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Drosophila melanogaster 61557 R-DME-74986 https://reactome.org/PathwayBrowser/#/R-DME-74986 Elongation of pre-rRNA transcript IEA Drosophila melanogaster 61557 R-DME-75850 https://reactome.org/PathwayBrowser/#/R-DME-75850 Addition of the third nucleotide on the nascent transcript IEA Drosophila melanogaster 61557 R-DME-75861 https://reactome.org/PathwayBrowser/#/R-DME-75861 NTP Binds Active Site of RNA Polymerase II IEA Drosophila melanogaster 61557 R-DME-75866 https://reactome.org/PathwayBrowser/#/R-DME-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Drosophila melanogaster 61557 R-DME-75869 https://reactome.org/PathwayBrowser/#/R-DME-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Drosophila melanogaster 61557 R-DME-75873 https://reactome.org/PathwayBrowser/#/R-DME-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Drosophila melanogaster 61557 R-DME-76576 https://reactome.org/PathwayBrowser/#/R-DME-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Drosophila melanogaster 61557 R-DME-9613497 https://reactome.org/PathwayBrowser/#/R-DME-9613497 Unwinding DNA for the nascent transcript IEA Drosophila melanogaster 61557 R-DRE-6806877 https://reactome.org/PathwayBrowser/#/R-DRE-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Danio rerio 61557 R-GGA-111264 https://reactome.org/PathwayBrowser/#/R-GGA-111264 Addition of nucleotides between position +11 and +30 IEA Gallus gallus 61557 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus 61557 R-GGA-112392 https://reactome.org/PathwayBrowser/#/R-GGA-112392 Resumption of elongation after recovery from pausing IEA Gallus gallus 61557 R-GGA-112395 https://reactome.org/PathwayBrowser/#/R-GGA-112395 Abortive termination of elongation after arrest IEA Gallus gallus 61557 R-GGA-112396 https://reactome.org/PathwayBrowser/#/R-GGA-112396 Separation of elongating transcript from template IEA Gallus gallus 61557 R-GGA-113402 https://reactome.org/PathwayBrowser/#/R-GGA-113402 Formation of DSIF:NELF:early elongation complex IEA Gallus gallus 61557 R-GGA-113411 https://reactome.org/PathwayBrowser/#/R-GGA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Gallus gallus 61557 R-GGA-113412 https://reactome.org/PathwayBrowser/#/R-GGA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Gallus gallus 61557 R-GGA-113413 https://reactome.org/PathwayBrowser/#/R-GGA-113413 TFIIS-mediated recovery of elongation from arrest IEA Gallus gallus 61557 R-GGA-113414 https://reactome.org/PathwayBrowser/#/R-GGA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Gallus gallus 61557 R-GGA-174425 https://reactome.org/PathwayBrowser/#/R-GGA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Gallus gallus 61557 R-GGA-6806877 https://reactome.org/PathwayBrowser/#/R-GGA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Gallus gallus 61557 R-GGA-68913 https://reactome.org/PathwayBrowser/#/R-GGA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Gallus gallus 61557 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus 61557 R-GGA-75850 https://reactome.org/PathwayBrowser/#/R-GGA-75850 Addition of the third nucleotide on the nascent transcript IEA Gallus gallus 61557 R-GGA-75861 https://reactome.org/PathwayBrowser/#/R-GGA-75861 NTP Binds Active Site of RNA Polymerase II IEA Gallus gallus 61557 R-GGA-75866 https://reactome.org/PathwayBrowser/#/R-GGA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Gallus gallus 61557 R-GGA-75869 https://reactome.org/PathwayBrowser/#/R-GGA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Gallus gallus 61557 R-GGA-75873 https://reactome.org/PathwayBrowser/#/R-GGA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Gallus gallus 61557 R-GGA-76576 https://reactome.org/PathwayBrowser/#/R-GGA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Gallus gallus 61557 R-GGA-8850846 https://reactome.org/PathwayBrowser/#/R-GGA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Gallus gallus 61557 R-GGA-8851110 https://reactome.org/PathwayBrowser/#/R-GGA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Gallus gallus 61557 R-GGA-9613497 https://reactome.org/PathwayBrowser/#/R-GGA-9613497 Unwinding DNA for the nascent transcript IEA Gallus gallus 61557 R-HSA-111264 https://reactome.org/PathwayBrowser/#/R-HSA-111264 Addition of nucleotides between position +11 and +30 TAS Homo sapiens 61557 R-HSA-112153 https://reactome.org/PathwayBrowser/#/R-HSA-112153 RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters IEA Homo sapiens 61557 R-HSA-112155 https://reactome.org/PathwayBrowser/#/R-HSA-112155 RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters IEA Homo sapiens 61557 R-HSA-112156 https://reactome.org/PathwayBrowser/#/R-HSA-112156 RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters IEA Homo sapiens 61557 R-HSA-112385 https://reactome.org/PathwayBrowser/#/R-HSA-112385 Addition of nucleotides leads to transcript elongation TAS Homo sapiens 61557 R-HSA-112392 https://reactome.org/PathwayBrowser/#/R-HSA-112392 Resumption of elongation after recovery from pausing TAS Homo sapiens 61557 R-HSA-112395 https://reactome.org/PathwayBrowser/#/R-HSA-112395 Abortive termination of elongation after arrest TAS Homo sapiens 61557 R-HSA-112396 https://reactome.org/PathwayBrowser/#/R-HSA-112396 Separation of elongating transcript from template TAS Homo sapiens 61557 R-HSA-113402 https://reactome.org/PathwayBrowser/#/R-HSA-113402 Formation of DSIF:NELF:early elongation complex TAS Homo sapiens 61557 R-HSA-113411 https://reactome.org/PathwayBrowser/#/R-HSA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing TAS Homo sapiens 61557 R-HSA-113412 https://reactome.org/PathwayBrowser/#/R-HSA-113412 Pol II elongation complex moves on the template as transcript elongates TAS Homo sapiens 61557 R-HSA-113413 https://reactome.org/PathwayBrowser/#/R-HSA-113413 TFIIS-mediated recovery of elongation from arrest TAS Homo sapiens 61557 R-HSA-113414 https://reactome.org/PathwayBrowser/#/R-HSA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest TAS Homo sapiens 61557 R-HSA-113429 https://reactome.org/PathwayBrowser/#/R-HSA-113429 Elongating transcript encounters a lesion in the template TAS Homo sapiens 61557 R-HSA-113446 https://reactome.org/PathwayBrowser/#/R-HSA-113446 Initiation of RNA Polymerase III Productive Transcription IEA Homo sapiens 61557 R-HSA-113451 https://reactome.org/PathwayBrowser/#/R-HSA-113451 Resumption of RNA Polymerase III Productive Transcription IEA Homo sapiens 61557 R-HSA-113705 https://reactome.org/PathwayBrowser/#/R-HSA-113705 RNA Polymerase III Productive Transcription IEA Homo sapiens 61557 R-HSA-167076 https://reactome.org/PathwayBrowser/#/R-HSA-167076 2-4 nt.backtracking of Pol II complex on the HIV-1 template leading to elongation pausing IEA Homo sapiens 61557 R-HSA-167085 https://reactome.org/PathwayBrowser/#/R-HSA-167085 Formation of DSIF:NELF:HIV-1 early elongation complex IEA Homo sapiens 61557 R-HSA-167087 https://reactome.org/PathwayBrowser/#/R-HSA-167087 Limited elongation of the HIV-1 transcript IEA Homo sapiens 61557 R-HSA-167090 https://reactome.org/PathwayBrowser/#/R-HSA-167090 7-14 nt. Backtracking of Pol II complex on the HIV-1 template leading to elongation arrest IEA Homo sapiens 61557 R-HSA-167113 https://reactome.org/PathwayBrowser/#/R-HSA-167113 Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition IEA Homo sapiens 61557 R-HSA-167115 https://reactome.org/PathwayBrowser/#/R-HSA-167115 Addition of nucleotides between position +11 and +30 on HIV-1 transcript IEA Homo sapiens 61557 R-HSA-167117 https://reactome.org/PathwayBrowser/#/R-HSA-167117 Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition IEA Homo sapiens 61557 R-HSA-167118 https://reactome.org/PathwayBrowser/#/R-HSA-167118 NTP binds active site of RNA Polymerase II in HIV-1 open pre-initiation complex IEA Homo sapiens 61557 R-HSA-167121 https://reactome.org/PathwayBrowser/#/R-HSA-167121 Addition of the third nucleotide on the nascent HIV-1 transcript IEA Homo sapiens 61557 R-HSA-167130 https://reactome.org/PathwayBrowser/#/R-HSA-167130 Nucleophillic attack by 3'-hydroxyl oxygen of nascent HIV-1 transcript on the Alpha phosphate of NTP IEA Homo sapiens 61557 R-HSA-167136 https://reactome.org/PathwayBrowser/#/R-HSA-167136 Addition of nucleotides 5 through 9 on the growing HIV-1 transcript IEA Homo sapiens 61557 R-HSA-167147 https://reactome.org/PathwayBrowser/#/R-HSA-167147 Separation of abortive HIV-1 transcript from template IEA Homo sapiens 61557 R-HSA-167148 https://reactome.org/PathwayBrowser/#/R-HSA-167148 TFIIS-mediated recovery of elongation from arrest IEA Homo sapiens 61557 R-HSA-167150 https://reactome.org/PathwayBrowser/#/R-HSA-167150 Resumption of elongation of HIV-1 transcript after recovery from pausing IEA Homo sapiens 61557 R-HSA-167181 https://reactome.org/PathwayBrowser/#/R-HSA-167181 Addition of nucleotides leads to HIV-1 transcript elongation IEA Homo sapiens 61557 R-HSA-167192 https://reactome.org/PathwayBrowser/#/R-HSA-167192 Pol II elongation complex moves on the HIV-1 template as transcript elongates IEA Homo sapiens 61557 R-HSA-167197 https://reactome.org/PathwayBrowser/#/R-HSA-167197 Separation of elongating HIV-1 transcript from template IEA Homo sapiens 61557 R-HSA-167282 https://reactome.org/PathwayBrowser/#/R-HSA-167282 2-4 nt.backtracking of Pol II complex on the HIV-1 template leading to elongation pausing IEA Homo sapiens 61557 R-HSA-167284 https://reactome.org/PathwayBrowser/#/R-HSA-167284 7-14 nt. Backtracking of Pol II complex on the HIV-1 template leading to elongation arrest IEA Homo sapiens 61557 R-HSA-167288 https://reactome.org/PathwayBrowser/#/R-HSA-167288 TFIIS-mediated recovery of HIV-1 elongation from arrest IEA Homo sapiens 61557 R-HSA-167292 https://reactome.org/PathwayBrowser/#/R-HSA-167292 Resumption of elongation of HIV-1 transcript after recovery from pausing IEA Homo sapiens 61557 R-HSA-167459 https://reactome.org/PathwayBrowser/#/R-HSA-167459 Abortive termination of HIV-1 elongation after arrest (Tat-containing elongation complex) IEA Homo sapiens 61557 R-HSA-167481 https://reactome.org/PathwayBrowser/#/R-HSA-167481 Abortive termination of HIV-1 elongation after arrest IEA Homo sapiens 61557 R-HSA-168301 https://reactome.org/PathwayBrowser/#/R-HSA-168301 Elongation, Polyadenylation and Termination TAS Homo sapiens 61557 R-HSA-174425 https://reactome.org/PathwayBrowser/#/R-HSA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere TAS Homo sapiens 61557 R-HSA-192624 https://reactome.org/PathwayBrowser/#/R-HSA-192624 cRNA Extension TAS Homo sapiens 61557 R-HSA-192832 https://reactome.org/PathwayBrowser/#/R-HSA-192832 Initiation of cRNA Synthesis TAS Homo sapiens 61557 R-HSA-192851 https://reactome.org/PathwayBrowser/#/R-HSA-192851 vRNA Extension TAS Homo sapiens 61557 R-HSA-6806877 https://reactome.org/PathwayBrowser/#/R-HSA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs TAS Homo sapiens 61557 R-HSA-68913 https://reactome.org/PathwayBrowser/#/R-HSA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin TAS Homo sapiens 61557 R-HSA-74986 https://reactome.org/PathwayBrowser/#/R-HSA-74986 Elongation of pre-rRNA transcript TAS Homo sapiens 61557 R-HSA-75850 https://reactome.org/PathwayBrowser/#/R-HSA-75850 Addition of the third nucleotide on the nascent transcript TAS Homo sapiens 61557 R-HSA-75861 https://reactome.org/PathwayBrowser/#/R-HSA-75861 NTP Binds Active Site of RNA Polymerase II TAS Homo sapiens 61557 R-HSA-75866 https://reactome.org/PathwayBrowser/#/R-HSA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP TAS Homo sapiens 61557 R-HSA-75869 https://reactome.org/PathwayBrowser/#/R-HSA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition TAS Homo sapiens 61557 R-HSA-75873 https://reactome.org/PathwayBrowser/#/R-HSA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript TAS Homo sapiens 61557 R-HSA-76576 https://reactome.org/PathwayBrowser/#/R-HSA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition TAS Homo sapiens 61557 R-HSA-8850846 https://reactome.org/PathwayBrowser/#/R-HSA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates TAS Homo sapiens 61557 R-HSA-8851110 https://reactome.org/PathwayBrowser/#/R-HSA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates TAS Homo sapiens 61557 R-HSA-9613490 https://reactome.org/PathwayBrowser/#/R-HSA-9613490 Unwinding of DNA for the nascent HIV-1 transcript: Second Transition IEA Homo sapiens 61557 R-HSA-9613497 https://reactome.org/PathwayBrowser/#/R-HSA-9613497 Unwinding DNA for the nascent transcript TAS Homo sapiens 61557 R-HSA-9613498 https://reactome.org/PathwayBrowser/#/R-HSA-9613498 Unwinding of DNA for the nascent HIV-1 transcript IEA Homo sapiens 61557 R-HSA-9681651 https://reactome.org/PathwayBrowser/#/R-HSA-9681651 nsp8 generates RNA primers TAS Homo sapiens 61557 R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 61557 R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 61557 R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 61557 R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 61557 R-HSA-9685639 https://reactome.org/PathwayBrowser/#/R-HSA-9685639 Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching TAS Homo sapiens 61557 R-HSA-9685681 https://reactome.org/PathwayBrowser/#/R-HSA-9685681 Synthesis of SARS-CoV-1 plus strand subgenomic mRNAs TAS Homo sapiens 61557 R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 61557 R-HSA-9694344 https://reactome.org/PathwayBrowser/#/R-HSA-9694344 Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching IEA Homo sapiens 61557 R-HSA-9694506 https://reactome.org/PathwayBrowser/#/R-HSA-9694506 Synthesis of SARS-CoV-2 plus strand subgenomic mRNAs TAS Homo sapiens 61557 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 61557 R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 61557 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 61557 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 61557 R-HSA-9828639 https://reactome.org/PathwayBrowser/#/R-HSA-9828639 Transcription of respiratory syncytial virus subgenomic positive sense mRNAs TAS Homo sapiens 61557 R-HSA-9834719 https://reactome.org/PathwayBrowser/#/R-HSA-9834719 Synthesis of negative sense genomic RNA of respiratory syncytial virus TAS Homo sapiens 61557 R-HSA-9834736 https://reactome.org/PathwayBrowser/#/R-HSA-9834736 Synthesis of antigenomic RNA of human respiratory syncytial virus TAS Homo sapiens 61557 R-HSA-9837511 https://reactome.org/PathwayBrowser/#/R-HSA-9837511 Abortive replication of hRSV A TAS Homo sapiens 61557 R-MMU-111264 https://reactome.org/PathwayBrowser/#/R-MMU-111264 Addition of nucleotides between position +11 and +30 IEA Mus musculus 61557 R-MMU-112385 https://reactome.org/PathwayBrowser/#/R-MMU-112385 Addition of nucleotides leads to transcript elongation IEA Mus musculus 61557 R-MMU-112392 https://reactome.org/PathwayBrowser/#/R-MMU-112392 Resumption of elongation after recovery from pausing IEA Mus musculus 61557 R-MMU-112395 https://reactome.org/PathwayBrowser/#/R-MMU-112395 Abortive termination of elongation after arrest IEA Mus musculus 61557 R-MMU-112396 https://reactome.org/PathwayBrowser/#/R-MMU-112396 Separation of elongating transcript from template IEA Mus musculus 61557 R-MMU-113402 https://reactome.org/PathwayBrowser/#/R-MMU-113402 Formation of DSIF:NELF:early elongation complex IEA Mus musculus 61557 R-MMU-113411 https://reactome.org/PathwayBrowser/#/R-MMU-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Mus musculus 61557 R-MMU-113412 https://reactome.org/PathwayBrowser/#/R-MMU-113412 Pol II elongation complex moves on the template as transcript elongates IEA Mus musculus 61557 R-MMU-113413 https://reactome.org/PathwayBrowser/#/R-MMU-113413 TFIIS-mediated recovery of elongation from arrest IEA Mus musculus 61557 R-MMU-113414 https://reactome.org/PathwayBrowser/#/R-MMU-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Mus musculus 61557 R-MMU-113429 https://reactome.org/PathwayBrowser/#/R-MMU-113429 Elongating transcript encounters a lesion in the template IEA Mus musculus 61557 R-MMU-174425 https://reactome.org/PathwayBrowser/#/R-MMU-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Mus musculus 61557 R-MMU-6806877 https://reactome.org/PathwayBrowser/#/R-MMU-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Mus musculus 61557 R-MMU-68913 https://reactome.org/PathwayBrowser/#/R-MMU-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Mus musculus 61557 R-MMU-74986 https://reactome.org/PathwayBrowser/#/R-MMU-74986 Elongation of pre-rRNA transcript IEA Mus musculus 61557 R-MMU-75850 https://reactome.org/PathwayBrowser/#/R-MMU-75850 Addition of the third nucleotide on the nascent transcript IEA Mus musculus 61557 R-MMU-75861 https://reactome.org/PathwayBrowser/#/R-MMU-75861 NTP Binds Active Site of RNA Polymerase II IEA Mus musculus 61557 R-MMU-75866 https://reactome.org/PathwayBrowser/#/R-MMU-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Mus musculus 61557 R-MMU-75869 https://reactome.org/PathwayBrowser/#/R-MMU-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Mus musculus 61557 R-MMU-75873 https://reactome.org/PathwayBrowser/#/R-MMU-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Mus musculus 61557 R-MMU-76576 https://reactome.org/PathwayBrowser/#/R-MMU-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Mus musculus 61557 R-MMU-8850846 https://reactome.org/PathwayBrowser/#/R-MMU-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Mus musculus 61557 R-MMU-8851110 https://reactome.org/PathwayBrowser/#/R-MMU-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Mus musculus 61557 R-MMU-9613497 https://reactome.org/PathwayBrowser/#/R-MMU-9613497 Unwinding DNA for the nascent transcript IEA Mus musculus 61557 R-PFA-111264 https://reactome.org/PathwayBrowser/#/R-PFA-111264 Addition of nucleotides between position +11 and +30 IEA Plasmodium falciparum 61557 R-PFA-6806877 https://reactome.org/PathwayBrowser/#/R-PFA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Plasmodium falciparum 61557 R-PFA-68913 https://reactome.org/PathwayBrowser/#/R-PFA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Plasmodium falciparum 61557 R-PFA-76576 https://reactome.org/PathwayBrowser/#/R-PFA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Plasmodium falciparum 61557 R-PFA-8850846 https://reactome.org/PathwayBrowser/#/R-PFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 61557 R-PFA-8851110 https://reactome.org/PathwayBrowser/#/R-PFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 61557 R-RNO-111264 https://reactome.org/PathwayBrowser/#/R-RNO-111264 Addition of nucleotides between position +11 and +30 IEA Rattus norvegicus 61557 R-RNO-112385 https://reactome.org/PathwayBrowser/#/R-RNO-112385 Addition of nucleotides leads to transcript elongation IEA Rattus norvegicus 61557 R-RNO-112392 https://reactome.org/PathwayBrowser/#/R-RNO-112392 Resumption of elongation after recovery from pausing IEA Rattus norvegicus 61557 R-RNO-112395 https://reactome.org/PathwayBrowser/#/R-RNO-112395 Abortive termination of elongation after arrest IEA Rattus norvegicus 61557 R-RNO-112396 https://reactome.org/PathwayBrowser/#/R-RNO-112396 Separation of elongating transcript from template IEA Rattus norvegicus 61557 R-RNO-113402 https://reactome.org/PathwayBrowser/#/R-RNO-113402 Formation of DSIF:NELF:early elongation complex IEA Rattus norvegicus 61557 R-RNO-113411 https://reactome.org/PathwayBrowser/#/R-RNO-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Rattus norvegicus 61557 R-RNO-113412 https://reactome.org/PathwayBrowser/#/R-RNO-113412 Pol II elongation complex moves on the template as transcript elongates IEA Rattus norvegicus 61557 R-RNO-113413 https://reactome.org/PathwayBrowser/#/R-RNO-113413 TFIIS-mediated recovery of elongation from arrest IEA Rattus norvegicus 61557 R-RNO-113414 https://reactome.org/PathwayBrowser/#/R-RNO-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Rattus norvegicus 61557 R-RNO-113429 https://reactome.org/PathwayBrowser/#/R-RNO-113429 Elongating transcript encounters a lesion in the template IEA Rattus norvegicus 61557 R-RNO-174425 https://reactome.org/PathwayBrowser/#/R-RNO-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Rattus norvegicus 61557 R-RNO-6806877 https://reactome.org/PathwayBrowser/#/R-RNO-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Rattus norvegicus 61557 R-RNO-68913 https://reactome.org/PathwayBrowser/#/R-RNO-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Rattus norvegicus 61557 R-RNO-74986 https://reactome.org/PathwayBrowser/#/R-RNO-74986 Elongation of pre-rRNA transcript IEA Rattus norvegicus 61557 R-RNO-75850 https://reactome.org/PathwayBrowser/#/R-RNO-75850 Addition of the third nucleotide on the nascent transcript IEA Rattus norvegicus 61557 R-RNO-75861 https://reactome.org/PathwayBrowser/#/R-RNO-75861 NTP Binds Active Site of RNA Polymerase II IEA Rattus norvegicus 61557 R-RNO-75866 https://reactome.org/PathwayBrowser/#/R-RNO-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Rattus norvegicus 61557 R-RNO-75869 https://reactome.org/PathwayBrowser/#/R-RNO-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Rattus norvegicus 61557 R-RNO-75873 https://reactome.org/PathwayBrowser/#/R-RNO-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Rattus norvegicus 61557 R-RNO-76576 https://reactome.org/PathwayBrowser/#/R-RNO-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Rattus norvegicus 61557 R-RNO-8850846 https://reactome.org/PathwayBrowser/#/R-RNO-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 61557 R-RNO-8851110 https://reactome.org/PathwayBrowser/#/R-RNO-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 61557 R-RNO-9613497 https://reactome.org/PathwayBrowser/#/R-RNO-9613497 Unwinding DNA for the nascent transcript IEA Rattus norvegicus 61557 R-SCE-111264 https://reactome.org/PathwayBrowser/#/R-SCE-111264 Addition of nucleotides between position +11 and +30 IEA Saccharomyces cerevisiae 61557 R-SCE-111942 https://reactome.org/PathwayBrowser/#/R-SCE-111942 RNA Polymerase III Initiation At a Simple Start Sequence TAS Saccharomyces cerevisiae 61557 R-SCE-112466 https://reactome.org/PathwayBrowser/#/R-SCE-112466 RNA Polymerase III Transcriptional Pause at Terminator Sequence TAS Saccharomyces cerevisiae 61557 R-SCE-6806877 https://reactome.org/PathwayBrowser/#/R-SCE-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Saccharomyces cerevisiae 61557 R-SCE-68913 https://reactome.org/PathwayBrowser/#/R-SCE-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Saccharomyces cerevisiae 61557 R-SCE-74986 https://reactome.org/PathwayBrowser/#/R-SCE-74986 Elongation of pre-rRNA transcript IEA Saccharomyces cerevisiae 61557 R-SCE-75850 https://reactome.org/PathwayBrowser/#/R-SCE-75850 Addition of the third nucleotide on the nascent transcript IEA Saccharomyces cerevisiae 61557 R-SCE-75861 https://reactome.org/PathwayBrowser/#/R-SCE-75861 NTP Binds Active Site of RNA Polymerase II IEA Saccharomyces cerevisiae 61557 R-SCE-75866 https://reactome.org/PathwayBrowser/#/R-SCE-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Saccharomyces cerevisiae 61557 R-SCE-75869 https://reactome.org/PathwayBrowser/#/R-SCE-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Saccharomyces cerevisiae 61557 R-SCE-75873 https://reactome.org/PathwayBrowser/#/R-SCE-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Saccharomyces cerevisiae 61557 R-SCE-76576 https://reactome.org/PathwayBrowser/#/R-SCE-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Saccharomyces cerevisiae 61557 R-SCE-9613497 https://reactome.org/PathwayBrowser/#/R-SCE-9613497 Unwinding DNA for the nascent transcript IEA Saccharomyces cerevisiae 61557 R-SPO-111264 https://reactome.org/PathwayBrowser/#/R-SPO-111264 Addition of nucleotides between position +11 and +30 IEA Schizosaccharomyces pombe 61557 R-SPO-6806877 https://reactome.org/PathwayBrowser/#/R-SPO-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Schizosaccharomyces pombe 61557 R-SPO-68913 https://reactome.org/PathwayBrowser/#/R-SPO-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Schizosaccharomyces pombe 61557 R-SPO-74986 https://reactome.org/PathwayBrowser/#/R-SPO-74986 Elongation of pre-rRNA transcript IEA Schizosaccharomyces pombe 61557 R-SPO-75850 https://reactome.org/PathwayBrowser/#/R-SPO-75850 Addition of the third nucleotide on the nascent transcript IEA Schizosaccharomyces pombe 61557 R-SPO-75861 https://reactome.org/PathwayBrowser/#/R-SPO-75861 NTP Binds Active Site of RNA Polymerase II IEA Schizosaccharomyces pombe 61557 R-SPO-75866 https://reactome.org/PathwayBrowser/#/R-SPO-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Schizosaccharomyces pombe 61557 R-SPO-75869 https://reactome.org/PathwayBrowser/#/R-SPO-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Schizosaccharomyces pombe 61557 R-SPO-75873 https://reactome.org/PathwayBrowser/#/R-SPO-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Schizosaccharomyces pombe 61557 R-SPO-76576 https://reactome.org/PathwayBrowser/#/R-SPO-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Schizosaccharomyces pombe 61557 R-SPO-9613497 https://reactome.org/PathwayBrowser/#/R-SPO-9613497 Unwinding DNA for the nascent transcript IEA Schizosaccharomyces pombe 61557 R-SSC-111264 https://reactome.org/PathwayBrowser/#/R-SSC-111264 Addition of nucleotides between position +11 and +30 IEA Sus scrofa 61557 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa 61557 R-SSC-112392 https://reactome.org/PathwayBrowser/#/R-SSC-112392 Resumption of elongation after recovery from pausing IEA Sus scrofa 61557 R-SSC-112395 https://reactome.org/PathwayBrowser/#/R-SSC-112395 Abortive termination of elongation after arrest IEA Sus scrofa 61557 R-SSC-112396 https://reactome.org/PathwayBrowser/#/R-SSC-112396 Separation of elongating transcript from template IEA Sus scrofa 61557 R-SSC-113402 https://reactome.org/PathwayBrowser/#/R-SSC-113402 Formation of DSIF:NELF:early elongation complex IEA Sus scrofa 61557 R-SSC-113411 https://reactome.org/PathwayBrowser/#/R-SSC-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Sus scrofa 61557 R-SSC-113412 https://reactome.org/PathwayBrowser/#/R-SSC-113412 Pol II elongation complex moves on the template as transcript elongates IEA Sus scrofa 61557 R-SSC-113413 https://reactome.org/PathwayBrowser/#/R-SSC-113413 TFIIS-mediated recovery of elongation from arrest IEA Sus scrofa 61557 R-SSC-113414 https://reactome.org/PathwayBrowser/#/R-SSC-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Sus scrofa 61557 R-SSC-113429 https://reactome.org/PathwayBrowser/#/R-SSC-113429 Elongating transcript encounters a lesion in the template IEA Sus scrofa 61557 R-SSC-174425 https://reactome.org/PathwayBrowser/#/R-SSC-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Sus scrofa 61557 R-SSC-6806877 https://reactome.org/PathwayBrowser/#/R-SSC-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Sus scrofa 61557 R-SSC-68913 https://reactome.org/PathwayBrowser/#/R-SSC-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Sus scrofa 61557 R-SSC-74986 https://reactome.org/PathwayBrowser/#/R-SSC-74986 Elongation of pre-rRNA transcript IEA Sus scrofa 61557 R-SSC-75850 https://reactome.org/PathwayBrowser/#/R-SSC-75850 Addition of the third nucleotide on the nascent transcript IEA Sus scrofa 61557 R-SSC-75861 https://reactome.org/PathwayBrowser/#/R-SSC-75861 NTP Binds Active Site of RNA Polymerase II IEA Sus scrofa 61557 R-SSC-75866 https://reactome.org/PathwayBrowser/#/R-SSC-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Sus scrofa 61557 R-SSC-75869 https://reactome.org/PathwayBrowser/#/R-SSC-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Sus scrofa 61557 R-SSC-75873 https://reactome.org/PathwayBrowser/#/R-SSC-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Sus scrofa 61557 R-SSC-76576 https://reactome.org/PathwayBrowser/#/R-SSC-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Sus scrofa 61557 R-SSC-8850846 https://reactome.org/PathwayBrowser/#/R-SSC-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Sus scrofa 61557 R-SSC-8851110 https://reactome.org/PathwayBrowser/#/R-SSC-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Sus scrofa 61557 R-SSC-9613497 https://reactome.org/PathwayBrowser/#/R-SSC-9613497 Unwinding DNA for the nascent transcript IEA Sus scrofa 61557 R-XTR-111264 https://reactome.org/PathwayBrowser/#/R-XTR-111264 Addition of nucleotides between position +11 and +30 IEA Xenopus tropicalis 61557 R-XTR-112385 https://reactome.org/PathwayBrowser/#/R-XTR-112385 Addition of nucleotides leads to transcript elongation IEA Xenopus tropicalis 61557 R-XTR-112392 https://reactome.org/PathwayBrowser/#/R-XTR-112392 Resumption of elongation after recovery from pausing IEA Xenopus tropicalis 61557 R-XTR-112395 https://reactome.org/PathwayBrowser/#/R-XTR-112395 Abortive termination of elongation after arrest IEA Xenopus tropicalis 61557 R-XTR-112396 https://reactome.org/PathwayBrowser/#/R-XTR-112396 Separation of elongating transcript from template IEA Xenopus tropicalis 61557 R-XTR-113402 https://reactome.org/PathwayBrowser/#/R-XTR-113402 Formation of DSIF:NELF:early elongation complex IEA Xenopus tropicalis 61557 R-XTR-113411 https://reactome.org/PathwayBrowser/#/R-XTR-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Xenopus tropicalis 61557 R-XTR-113412 https://reactome.org/PathwayBrowser/#/R-XTR-113412 Pol II elongation complex moves on the template as transcript elongates IEA Xenopus tropicalis 61557 R-XTR-113413 https://reactome.org/PathwayBrowser/#/R-XTR-113413 TFIIS-mediated recovery of elongation from arrest IEA Xenopus tropicalis 61557 R-XTR-113414 https://reactome.org/PathwayBrowser/#/R-XTR-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Xenopus tropicalis 61557 R-XTR-6806877 https://reactome.org/PathwayBrowser/#/R-XTR-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Xenopus tropicalis 61557 R-XTR-74986 https://reactome.org/PathwayBrowser/#/R-XTR-74986 Elongation of pre-rRNA transcript IEA Xenopus tropicalis 61557 R-XTR-75850 https://reactome.org/PathwayBrowser/#/R-XTR-75850 Addition of the third nucleotide on the nascent transcript IEA Xenopus tropicalis 61557 R-XTR-75861 https://reactome.org/PathwayBrowser/#/R-XTR-75861 NTP Binds Active Site of RNA Polymerase II IEA Xenopus tropicalis 61557 R-XTR-75866 https://reactome.org/PathwayBrowser/#/R-XTR-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Xenopus tropicalis 61557 R-XTR-75869 https://reactome.org/PathwayBrowser/#/R-XTR-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Xenopus tropicalis 61557 R-XTR-76576 https://reactome.org/PathwayBrowser/#/R-XTR-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Xenopus tropicalis 61557 R-XTR-8850846 https://reactome.org/PathwayBrowser/#/R-XTR-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 61557 R-XTR-8851110 https://reactome.org/PathwayBrowser/#/R-XTR-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 61557 R-XTR-9613497 https://reactome.org/PathwayBrowser/#/R-XTR-9613497 Unwinding DNA for the nascent transcript IEA Xenopus tropicalis 61560 R-BTA-8866601 https://reactome.org/PathwayBrowser/#/R-BTA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Bos taurus 61560 R-CEL-8866601 https://reactome.org/PathwayBrowser/#/R-CEL-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Caenorhabditis elegans 61560 R-CFA-8866601 https://reactome.org/PathwayBrowser/#/R-CFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Canis familiaris 61560 R-DDI-8866601 https://reactome.org/PathwayBrowser/#/R-DDI-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Dictyostelium discoideum 61560 R-DME-8866601 https://reactome.org/PathwayBrowser/#/R-DME-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Drosophila melanogaster 61560 R-DRE-8866601 https://reactome.org/PathwayBrowser/#/R-DRE-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Danio rerio 61560 R-GGA-8866601 https://reactome.org/PathwayBrowser/#/R-GGA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Gallus gallus 61560 R-HSA-8866601 https://reactome.org/PathwayBrowser/#/R-HSA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate TAS Homo sapiens 61560 R-MMU-8866601 https://reactome.org/PathwayBrowser/#/R-MMU-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Mus musculus 61560 R-PFA-8866601 https://reactome.org/PathwayBrowser/#/R-PFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Plasmodium falciparum 61560 R-RNO-8866601 https://reactome.org/PathwayBrowser/#/R-RNO-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Rattus norvegicus 61560 R-SSC-8866601 https://reactome.org/PathwayBrowser/#/R-SSC-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Sus scrofa 61560 R-XTR-8866601 https://reactome.org/PathwayBrowser/#/R-XTR-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Xenopus tropicalis 61626 R-BTA-6799977 https://reactome.org/PathwayBrowser/#/R-BTA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Bos taurus 61626 R-CFA-6799977 https://reactome.org/PathwayBrowser/#/R-CFA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Canis familiaris 61626 R-DME-6799977 https://reactome.org/PathwayBrowser/#/R-DME-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Drosophila melanogaster 61626 R-DRE-6799977 https://reactome.org/PathwayBrowser/#/R-DRE-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Danio rerio 61626 R-GGA-6799977 https://reactome.org/PathwayBrowser/#/R-GGA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Gallus gallus 61626 R-HSA-6799977 https://reactome.org/PathwayBrowser/#/R-HSA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan TAS Homo sapiens 61626 R-MMU-6799977 https://reactome.org/PathwayBrowser/#/R-MMU-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Mus musculus 61626 R-RNO-6799977 https://reactome.org/PathwayBrowser/#/R-RNO-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Rattus norvegicus 61626 R-SSC-6799977 https://reactome.org/PathwayBrowser/#/R-SSC-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Sus scrofa 61626 R-XTR-6799977 https://reactome.org/PathwayBrowser/#/R-XTR-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Xenopus tropicalis 61694 R-BTA-1247910 https://reactome.org/PathwayBrowser/#/R-BTA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Bos taurus 61694 R-BTA-6785928 https://reactome.org/PathwayBrowser/#/R-BTA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Bos taurus 61694 R-BTA-8943279 https://reactome.org/PathwayBrowser/#/R-BTA-8943279 GGT dimers hydrolyse GSH IEA Bos taurus 61694 R-CEL-1247910 https://reactome.org/PathwayBrowser/#/R-CEL-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Caenorhabditis elegans 61694 R-CEL-6785928 https://reactome.org/PathwayBrowser/#/R-CEL-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Caenorhabditis elegans 61694 R-CEL-8943279 https://reactome.org/PathwayBrowser/#/R-CEL-8943279 GGT dimers hydrolyse GSH IEA Caenorhabditis elegans 61694 R-CFA-1247910 https://reactome.org/PathwayBrowser/#/R-CFA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Canis familiaris 61694 R-CFA-6785928 https://reactome.org/PathwayBrowser/#/R-CFA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Canis familiaris 61694 R-CFA-8943279 https://reactome.org/PathwayBrowser/#/R-CFA-8943279 GGT dimers hydrolyse GSH IEA Canis familiaris 61694 R-DDI-1247910 https://reactome.org/PathwayBrowser/#/R-DDI-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Dictyostelium discoideum 61694 R-DDI-6785928 https://reactome.org/PathwayBrowser/#/R-DDI-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Dictyostelium discoideum 61694 R-DME-1247910 https://reactome.org/PathwayBrowser/#/R-DME-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Drosophila melanogaster 61694 R-DME-6785928 https://reactome.org/PathwayBrowser/#/R-DME-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Drosophila melanogaster 61694 R-DME-8943279 https://reactome.org/PathwayBrowser/#/R-DME-8943279 GGT dimers hydrolyse GSH IEA Drosophila melanogaster 61694 R-DRE-1247910 https://reactome.org/PathwayBrowser/#/R-DRE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Danio rerio 61694 R-DRE-6785928 https://reactome.org/PathwayBrowser/#/R-DRE-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Danio rerio 61694 R-GGA-1247910 https://reactome.org/PathwayBrowser/#/R-GGA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Gallus gallus 61694 R-GGA-6785928 https://reactome.org/PathwayBrowser/#/R-GGA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Gallus gallus 61694 R-GGA-8943279 https://reactome.org/PathwayBrowser/#/R-GGA-8943279 GGT dimers hydrolyse GSH IEA Gallus gallus 61694 R-HSA-1247910 https://reactome.org/PathwayBrowser/#/R-HSA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly TAS Homo sapiens 61694 R-HSA-1247939 https://reactome.org/PathwayBrowser/#/R-HSA-1247939 CysGly translocates from extracellular region to cytosol TAS Homo sapiens 61694 R-HSA-6785928 https://reactome.org/PathwayBrowser/#/R-HSA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly TAS Homo sapiens 61694 R-HSA-8943279 https://reactome.org/PathwayBrowser/#/R-HSA-8943279 GGT dimers hydrolyse GSH TAS Homo sapiens 61694 R-MMU-1247910 https://reactome.org/PathwayBrowser/#/R-MMU-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Mus musculus 61694 R-MMU-6785928 https://reactome.org/PathwayBrowser/#/R-MMU-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Mus musculus 61694 R-MMU-8943279 https://reactome.org/PathwayBrowser/#/R-MMU-8943279 GGT dimers hydrolyse GSH IEA Mus musculus 61694 R-RNO-1247910 https://reactome.org/PathwayBrowser/#/R-RNO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Rattus norvegicus 61694 R-RNO-6785928 https://reactome.org/PathwayBrowser/#/R-RNO-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Rattus norvegicus 61694 R-RNO-8943279 https://reactome.org/PathwayBrowser/#/R-RNO-8943279 GGT dimers hydrolyse GSH IEA Rattus norvegicus 61694 R-SCE-1247910 https://reactome.org/PathwayBrowser/#/R-SCE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Saccharomyces cerevisiae 61694 R-SCE-6785928 https://reactome.org/PathwayBrowser/#/R-SCE-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Saccharomyces cerevisiae 61694 R-SCE-8943279 https://reactome.org/PathwayBrowser/#/R-SCE-8943279 GGT dimers hydrolyse GSH IEA Saccharomyces cerevisiae 61694 R-SPO-1247910 https://reactome.org/PathwayBrowser/#/R-SPO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Schizosaccharomyces pombe 61694 R-SPO-6785928 https://reactome.org/PathwayBrowser/#/R-SPO-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Schizosaccharomyces pombe 61694 R-SPO-8943279 https://reactome.org/PathwayBrowser/#/R-SPO-8943279 GGT dimers hydrolyse GSH IEA Schizosaccharomyces pombe 61694 R-SSC-1247910 https://reactome.org/PathwayBrowser/#/R-SSC-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Sus scrofa 61694 R-SSC-6785928 https://reactome.org/PathwayBrowser/#/R-SSC-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Sus scrofa 61694 R-SSC-8943279 https://reactome.org/PathwayBrowser/#/R-SSC-8943279 GGT dimers hydrolyse GSH IEA Sus scrofa 61694 R-XTR-1247910 https://reactome.org/PathwayBrowser/#/R-XTR-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Xenopus tropicalis 61694 R-XTR-6785928 https://reactome.org/PathwayBrowser/#/R-XTR-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Xenopus tropicalis 61711 R-BTA-9605682 https://reactome.org/PathwayBrowser/#/R-BTA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Bos taurus 61711 R-CEL-9605682 https://reactome.org/PathwayBrowser/#/R-CEL-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Caenorhabditis elegans 61711 R-CFA-9605682 https://reactome.org/PathwayBrowser/#/R-CFA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Canis familiaris 61711 R-DDI-9605682 https://reactome.org/PathwayBrowser/#/R-DDI-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Dictyostelium discoideum 61711 R-DME-9605682 https://reactome.org/PathwayBrowser/#/R-DME-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Drosophila melanogaster 61711 R-DRE-9605682 https://reactome.org/PathwayBrowser/#/R-DRE-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Danio rerio 61711 R-GGA-9605682 https://reactome.org/PathwayBrowser/#/R-GGA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Gallus gallus 61711 R-HSA-9605682 https://reactome.org/PathwayBrowser/#/R-HSA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX TAS Homo sapiens 61711 R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 61711 R-MMU-9605682 https://reactome.org/PathwayBrowser/#/R-MMU-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Mus musculus 61711 R-RNO-9605682 https://reactome.org/PathwayBrowser/#/R-RNO-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Rattus norvegicus 61711 R-SSC-9605682 https://reactome.org/PathwayBrowser/#/R-SSC-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Sus scrofa 61711 R-XTR-9605682 https://reactome.org/PathwayBrowser/#/R-XTR-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Xenopus tropicalis 61715 R-BTA-2995334 https://reactome.org/PathwayBrowser/#/R-BTA-2995334 COX15 transforms heme O to heme A IEA Bos taurus 61715 R-CEL-2995334 https://reactome.org/PathwayBrowser/#/R-CEL-2995334 COX15 transforms heme O to heme A IEA Caenorhabditis elegans 61715 R-CFA-2995334 https://reactome.org/PathwayBrowser/#/R-CFA-2995334 COX15 transforms heme O to heme A IEA Canis familiaris 61715 R-DDI-2995334 https://reactome.org/PathwayBrowser/#/R-DDI-2995334 COX15 transforms heme O to heme A IEA Dictyostelium discoideum 61715 R-DME-2995334 https://reactome.org/PathwayBrowser/#/R-DME-2995334 COX15 transforms heme O to heme A IEA Drosophila melanogaster 61715 R-GGA-2995334 https://reactome.org/PathwayBrowser/#/R-GGA-2995334 COX15 transforms heme O to heme A IEA Gallus gallus 61715 R-HSA-2995334 https://reactome.org/PathwayBrowser/#/R-HSA-2995334 COX15 transforms heme O to heme A TAS Homo sapiens 61715 R-MMU-2995334 https://reactome.org/PathwayBrowser/#/R-MMU-2995334 COX15 transforms heme O to heme A IEA Mus musculus 61715 R-PFA-2995334 https://reactome.org/PathwayBrowser/#/R-PFA-2995334 COX15 transforms heme O to heme A IEA Plasmodium falciparum 61715 R-RNO-2995334 https://reactome.org/PathwayBrowser/#/R-RNO-2995334 COX15 transforms heme O to heme A IEA Rattus norvegicus 61715 R-SCE-2995334 https://reactome.org/PathwayBrowser/#/R-SCE-2995334 COX15 transforms heme O to heme A IEA Saccharomyces cerevisiae 61715 R-SPO-2995334 https://reactome.org/PathwayBrowser/#/R-SPO-2995334 COX15 transforms heme O to heme A IEA Schizosaccharomyces pombe 61715 R-SSC-2995334 https://reactome.org/PathwayBrowser/#/R-SSC-2995334 COX15 transforms heme O to heme A IEA Sus scrofa 61715 R-XTR-2995334 https://reactome.org/PathwayBrowser/#/R-XTR-2995334 COX15 transforms heme O to heme A IEA Xenopus tropicalis 61723 R-BTA-196754 https://reactome.org/PathwayBrowser/#/R-BTA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Bos taurus 61723 R-BTA-196840 https://reactome.org/PathwayBrowser/#/R-BTA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Bos taurus 61723 R-BTA-9837419 https://reactome.org/PathwayBrowser/#/R-BTA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Bos taurus 61723 R-CEL-196754 https://reactome.org/PathwayBrowser/#/R-CEL-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Caenorhabditis elegans 61723 R-CEL-196840 https://reactome.org/PathwayBrowser/#/R-CEL-196840 3xPPCDC:3FMN decarboxylates PPC IEA Caenorhabditis elegans 61723 R-CEL-9837419 https://reactome.org/PathwayBrowser/#/R-CEL-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Caenorhabditis elegans 61723 R-CFA-196754 https://reactome.org/PathwayBrowser/#/R-CFA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Canis familiaris 61723 R-CFA-196840 https://reactome.org/PathwayBrowser/#/R-CFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Canis familiaris 61723 R-CFA-9837419 https://reactome.org/PathwayBrowser/#/R-CFA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Canis familiaris 61723 R-DDI-196754 https://reactome.org/PathwayBrowser/#/R-DDI-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Dictyostelium discoideum 61723 R-DDI-196840 https://reactome.org/PathwayBrowser/#/R-DDI-196840 3xPPCDC:3FMN decarboxylates PPC IEA Dictyostelium discoideum 61723 R-DDI-9837419 https://reactome.org/PathwayBrowser/#/R-DDI-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Dictyostelium discoideum 61723 R-DME-196840 https://reactome.org/PathwayBrowser/#/R-DME-196840 3xPPCDC:3FMN decarboxylates PPC IEA Drosophila melanogaster 61723 R-DRE-196754 https://reactome.org/PathwayBrowser/#/R-DRE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Danio rerio 61723 R-GGA-196754 https://reactome.org/PathwayBrowser/#/R-GGA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Gallus gallus 61723 R-GGA-196840 https://reactome.org/PathwayBrowser/#/R-GGA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Gallus gallus 61723 R-GGA-9837419 https://reactome.org/PathwayBrowser/#/R-GGA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Gallus gallus 61723 R-HSA-196754 https://reactome.org/PathwayBrowser/#/R-HSA-196754 COASY transfers an adenylyl group from ATP to PPANT TAS Homo sapiens 61723 R-HSA-196840 https://reactome.org/PathwayBrowser/#/R-HSA-196840 3xPPCDC:3FMN decarboxylates PPC TAS Homo sapiens 61723 R-HSA-6809354 https://reactome.org/PathwayBrowser/#/R-HSA-6809354 NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT IEA Homo sapiens 61723 R-HSA-8938314 https://reactome.org/PathwayBrowser/#/R-HSA-8938314 ENPPs hydrolyse CoA-SH to PPANT, PAP TAS Homo sapiens 61723 R-HSA-8939039 https://reactome.org/PathwayBrowser/#/R-HSA-8939039 PPANT translocates from extracellular region to cytosol TAS Homo sapiens 61723 R-HSA-9837354 https://reactome.org/PathwayBrowser/#/R-HSA-9837354 NUDT8 hydrolyzes CoA-SH to PPANT IEA Homo sapiens 61723 R-HSA-9837419 https://reactome.org/PathwayBrowser/#/R-HSA-9837419 PANK4 hydrolyzes PPANT to pantetheine TAS Homo sapiens 61723 R-MMU-196754 https://reactome.org/PathwayBrowser/#/R-MMU-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Mus musculus 61723 R-MMU-196840 https://reactome.org/PathwayBrowser/#/R-MMU-196840 3xPPCDC:3FMN decarboxylates PPC IEA Mus musculus 61723 R-MMU-6810452 https://reactome.org/PathwayBrowser/#/R-MMU-6810452 Nudt7 hydrolyses CoA-SH to 3',5'-ADP and PPANT TAS Mus musculus 61723 R-MMU-9837342 https://reactome.org/PathwayBrowser/#/R-MMU-9837342 Nudt8 hydrolyzes CoA-SH to PPANT TAS Mus musculus 61723 R-MMU-9837419 https://reactome.org/PathwayBrowser/#/R-MMU-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Mus musculus 61723 R-PFA-196840 https://reactome.org/PathwayBrowser/#/R-PFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Plasmodium falciparum 61723 R-PFA-9837419 https://reactome.org/PathwayBrowser/#/R-PFA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Plasmodium falciparum 61723 R-RNO-196754 https://reactome.org/PathwayBrowser/#/R-RNO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Rattus norvegicus 61723 R-RNO-196840 https://reactome.org/PathwayBrowser/#/R-RNO-196840 3xPPCDC:3FMN decarboxylates PPC IEA Rattus norvegicus 61723 R-RNO-9837419 https://reactome.org/PathwayBrowser/#/R-RNO-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Rattus norvegicus 61723 R-SCE-196754 https://reactome.org/PathwayBrowser/#/R-SCE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Saccharomyces cerevisiae 61723 R-SCE-196840 https://reactome.org/PathwayBrowser/#/R-SCE-196840 3xPPCDC:3FMN decarboxylates PPC IEA Saccharomyces cerevisiae 61723 R-SCE-9837419 https://reactome.org/PathwayBrowser/#/R-SCE-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Saccharomyces cerevisiae 61723 R-SPO-196754 https://reactome.org/PathwayBrowser/#/R-SPO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Schizosaccharomyces pombe 61723 R-SPO-9837419 https://reactome.org/PathwayBrowser/#/R-SPO-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Schizosaccharomyces pombe 61723 R-SSC-196754 https://reactome.org/PathwayBrowser/#/R-SSC-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Sus scrofa 61723 R-SSC-196840 https://reactome.org/PathwayBrowser/#/R-SSC-196840 3xPPCDC:3FMN decarboxylates PPC IEA Sus scrofa 61723 R-SSC-9837419 https://reactome.org/PathwayBrowser/#/R-SSC-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Sus scrofa 61723 R-XTR-196754 https://reactome.org/PathwayBrowser/#/R-XTR-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Xenopus tropicalis 61723 R-XTR-196840 https://reactome.org/PathwayBrowser/#/R-XTR-196840 3xPPCDC:3FMN decarboxylates PPC IEA Xenopus tropicalis 61727 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 61727 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 61727 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 61727 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 61727 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 61727 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 61727 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 61727 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 61727 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 61793 R-BTA-9605609 https://reactome.org/PathwayBrowser/#/R-BTA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Bos taurus 61793 R-CEL-9605609 https://reactome.org/PathwayBrowser/#/R-CEL-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Caenorhabditis elegans 61793 R-CFA-9605609 https://reactome.org/PathwayBrowser/#/R-CFA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Canis familiaris 61793 R-DDI-9605609 https://reactome.org/PathwayBrowser/#/R-DDI-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Dictyostelium discoideum 61793 R-DME-9605609 https://reactome.org/PathwayBrowser/#/R-DME-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Drosophila melanogaster 61793 R-HSA-9605609 https://reactome.org/PathwayBrowser/#/R-HSA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA TAS Homo sapiens 61793 R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 61793 R-SSC-9605609 https://reactome.org/PathwayBrowser/#/R-SSC-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Sus scrofa 61793 R-XTR-9605609 https://reactome.org/PathwayBrowser/#/R-XTR-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Xenopus tropicalis 61907 R-BTA-5690042 https://reactome.org/PathwayBrowser/#/R-BTA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 61907 R-BTA-5690043 https://reactome.org/PathwayBrowser/#/R-BTA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 61907 R-BTA-5690066 https://reactome.org/PathwayBrowser/#/R-BTA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 61907 R-BTA-5696004 https://reactome.org/PathwayBrowser/#/R-BTA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Bos taurus 61907 R-BTA-8848246 https://reactome.org/PathwayBrowser/#/R-BTA-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Bos taurus 61907 R-BTA-8848247 https://reactome.org/PathwayBrowser/#/R-BTA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Bos taurus 61907 R-CEL-5690042 https://reactome.org/PathwayBrowser/#/R-CEL-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 61907 R-CEL-5690043 https://reactome.org/PathwayBrowser/#/R-CEL-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 61907 R-CEL-5690066 https://reactome.org/PathwayBrowser/#/R-CEL-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 61907 R-CEL-5696004 https://reactome.org/PathwayBrowser/#/R-CEL-5696004 ACSF2 ligates CoA-SH to MCFA IEA Caenorhabditis elegans 61907 R-CEL-8848247 https://reactome.org/PathwayBrowser/#/R-CEL-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Caenorhabditis elegans 61907 R-CFA-5690042 https://reactome.org/PathwayBrowser/#/R-CFA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 61907 R-CFA-5690043 https://reactome.org/PathwayBrowser/#/R-CFA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 61907 R-CFA-5690066 https://reactome.org/PathwayBrowser/#/R-CFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 61907 R-CFA-5696004 https://reactome.org/PathwayBrowser/#/R-CFA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Canis familiaris 61907 R-CFA-8848246 https://reactome.org/PathwayBrowser/#/R-CFA-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Canis familiaris 61907 R-CFA-8848247 https://reactome.org/PathwayBrowser/#/R-CFA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Canis familiaris 61907 R-DDI-5690043 https://reactome.org/PathwayBrowser/#/R-DDI-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 61907 R-DDI-5690066 https://reactome.org/PathwayBrowser/#/R-DDI-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 61907 R-DDI-8848246 https://reactome.org/PathwayBrowser/#/R-DDI-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Dictyostelium discoideum 61907 R-DME-5690043 https://reactome.org/PathwayBrowser/#/R-DME-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 61907 R-DME-5690066 https://reactome.org/PathwayBrowser/#/R-DME-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 61907 R-DME-5696004 https://reactome.org/PathwayBrowser/#/R-DME-5696004 ACSF2 ligates CoA-SH to MCFA IEA Drosophila melanogaster 61907 R-DME-8848246 https://reactome.org/PathwayBrowser/#/R-DME-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Drosophila melanogaster 61907 R-DME-8848247 https://reactome.org/PathwayBrowser/#/R-DME-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Drosophila melanogaster 61907 R-DRE-5690042 https://reactome.org/PathwayBrowser/#/R-DRE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 61907 R-DRE-5690066 https://reactome.org/PathwayBrowser/#/R-DRE-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 61907 R-DRE-5696004 https://reactome.org/PathwayBrowser/#/R-DRE-5696004 ACSF2 ligates CoA-SH to MCFA IEA Danio rerio 61907 R-DRE-8848246 https://reactome.org/PathwayBrowser/#/R-DRE-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Danio rerio 61907 R-DRE-8848247 https://reactome.org/PathwayBrowser/#/R-DRE-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Danio rerio 61907 R-GGA-5690042 https://reactome.org/PathwayBrowser/#/R-GGA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 61907 R-GGA-5690043 https://reactome.org/PathwayBrowser/#/R-GGA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 61907 R-GGA-5690066 https://reactome.org/PathwayBrowser/#/R-GGA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 61907 R-GGA-5696004 https://reactome.org/PathwayBrowser/#/R-GGA-5696004 ACSF2 ligates CoA-SH to MCFA IEA Gallus gallus 61907 R-GGA-8848246 https://reactome.org/PathwayBrowser/#/R-GGA-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Gallus gallus 61907 R-GGA-8848247 https://reactome.org/PathwayBrowser/#/R-GGA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Gallus gallus 61907 R-HSA-5690042 https://reactome.org/PathwayBrowser/#/R-HSA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 61907 R-HSA-5690043 https://reactome.org/PathwayBrowser/#/R-HSA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 61907 R-HSA-5690066 https://reactome.org/PathwayBrowser/#/R-HSA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 61907 R-HSA-5696004 https://reactome.org/PathwayBrowser/#/R-HSA-5696004 ACSF2 ligates CoA-SH to MCFA TAS Homo sapiens 61907 R-HSA-8848246 https://reactome.org/PathwayBrowser/#/R-HSA-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA TAS Homo sapiens 61907 R-HSA-8848247 https://reactome.org/PathwayBrowser/#/R-HSA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA TAS Homo sapiens 61907 R-MMU-5690042 https://reactome.org/PathwayBrowser/#/R-MMU-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 61907 R-MMU-5690043 https://reactome.org/PathwayBrowser/#/R-MMU-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 61907 R-MMU-5690066 https://reactome.org/PathwayBrowser/#/R-MMU-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 61907 R-MMU-5696004 https://reactome.org/PathwayBrowser/#/R-MMU-5696004 ACSF2 ligates CoA-SH to MCFA IEA Mus musculus 61907 R-MMU-8848246 https://reactome.org/PathwayBrowser/#/R-MMU-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Mus musculus 61907 R-MMU-8848247 https://reactome.org/PathwayBrowser/#/R-MMU-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Mus musculus 61907 R-PFA-5690066 https://reactome.org/PathwayBrowser/#/R-PFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Plasmodium falciparum 61907 R-PFA-8848246 https://reactome.org/PathwayBrowser/#/R-PFA-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Plasmodium falciparum 61907 R-PFA-8848247 https://reactome.org/PathwayBrowser/#/R-PFA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Plasmodium falciparum 61907 R-RNO-5690042 https://reactome.org/PathwayBrowser/#/R-RNO-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 61907 R-RNO-5690043 https://reactome.org/PathwayBrowser/#/R-RNO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 61907 R-RNO-5690066 https://reactome.org/PathwayBrowser/#/R-RNO-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 61907 R-RNO-5696004 https://reactome.org/PathwayBrowser/#/R-RNO-5696004 ACSF2 ligates CoA-SH to MCFA IEA Rattus norvegicus 61907 R-RNO-8848246 https://reactome.org/PathwayBrowser/#/R-RNO-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Rattus norvegicus 61907 R-RNO-8848247 https://reactome.org/PathwayBrowser/#/R-RNO-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Rattus norvegicus 61907 R-SCE-5690042 https://reactome.org/PathwayBrowser/#/R-SCE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Saccharomyces cerevisiae 61907 R-SCE-8848246 https://reactome.org/PathwayBrowser/#/R-SCE-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Saccharomyces cerevisiae 61907 R-SPO-5690043 https://reactome.org/PathwayBrowser/#/R-SPO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Schizosaccharomyces pombe 61907 R-SPO-8848246 https://reactome.org/PathwayBrowser/#/R-SPO-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Schizosaccharomyces pombe 61907 R-SSC-5690042 https://reactome.org/PathwayBrowser/#/R-SSC-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 61907 R-SSC-5690043 https://reactome.org/PathwayBrowser/#/R-SSC-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 61907 R-SSC-5690066 https://reactome.org/PathwayBrowser/#/R-SSC-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 61907 R-SSC-5696004 https://reactome.org/PathwayBrowser/#/R-SSC-5696004 ACSF2 ligates CoA-SH to MCFA IEA Sus scrofa 61907 R-SSC-8848246 https://reactome.org/PathwayBrowser/#/R-SSC-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Sus scrofa 61907 R-SSC-8848247 https://reactome.org/PathwayBrowser/#/R-SSC-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Sus scrofa 61907 R-XTR-5690042 https://reactome.org/PathwayBrowser/#/R-XTR-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 61907 R-XTR-5690043 https://reactome.org/PathwayBrowser/#/R-XTR-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 61907 R-XTR-5690066 https://reactome.org/PathwayBrowser/#/R-XTR-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 61907 R-XTR-5696004 https://reactome.org/PathwayBrowser/#/R-XTR-5696004 ACSF2 ligates CoA-SH to MCFA IEA Xenopus tropicalis 61907 R-XTR-8848246 https://reactome.org/PathwayBrowser/#/R-XTR-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Xenopus tropicalis 61907 R-XTR-8848247 https://reactome.org/PathwayBrowser/#/R-XTR-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Xenopus tropicalis 61910 R-BTA-5696007 https://reactome.org/PathwayBrowser/#/R-BTA-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Bos taurus 61910 R-CFA-5695957 https://reactome.org/PathwayBrowser/#/R-CFA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Canis familiaris 61910 R-DDI-5695957 https://reactome.org/PathwayBrowser/#/R-DDI-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Dictyostelium discoideum 61910 R-DDI-5696007 https://reactome.org/PathwayBrowser/#/R-DDI-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Dictyostelium discoideum 61910 R-DME-5695957 https://reactome.org/PathwayBrowser/#/R-DME-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Drosophila melanogaster 61910 R-DME-5696007 https://reactome.org/PathwayBrowser/#/R-DME-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Drosophila melanogaster 61910 R-GGA-5695957 https://reactome.org/PathwayBrowser/#/R-GGA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Gallus gallus 61910 R-HSA-5695957 https://reactome.org/PathwayBrowser/#/R-HSA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA TAS Homo sapiens 61910 R-HSA-5696007 https://reactome.org/PathwayBrowser/#/R-HSA-5696007 ACSF3 ligates CoA-SH to VLCFA TAS Homo sapiens 61910 R-HSA-8875077 https://reactome.org/PathwayBrowser/#/R-HSA-8875077 SLC27A3 ligates CoA-SH to VLCFA IEA Homo sapiens 61910 R-MMU-5695957 https://reactome.org/PathwayBrowser/#/R-MMU-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Mus musculus 61910 R-MMU-5696007 https://reactome.org/PathwayBrowser/#/R-MMU-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Mus musculus 61910 R-MMU-8875095 https://reactome.org/PathwayBrowser/#/R-MMU-8875095 Slc27a3 ligates CoA to VLCFA TAS Mus musculus 61910 R-RNO-5695957 https://reactome.org/PathwayBrowser/#/R-RNO-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Rattus norvegicus 61910 R-RNO-5696007 https://reactome.org/PathwayBrowser/#/R-RNO-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Rattus norvegicus 61910 R-SSC-5695957 https://reactome.org/PathwayBrowser/#/R-SSC-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Sus scrofa 61910 R-SSC-5696007 https://reactome.org/PathwayBrowser/#/R-SSC-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Sus scrofa 62077 R-BTA-77325 https://reactome.org/PathwayBrowser/#/R-BTA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Bos taurus 62077 R-BTA-77327 https://reactome.org/PathwayBrowser/#/R-BTA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Bos taurus 62077 R-CEL-77325 https://reactome.org/PathwayBrowser/#/R-CEL-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Caenorhabditis elegans 62077 R-CFA-77325 https://reactome.org/PathwayBrowser/#/R-CFA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Canis familiaris 62077 R-CFA-77327 https://reactome.org/PathwayBrowser/#/R-CFA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Canis familiaris 62077 R-DDI-77325 https://reactome.org/PathwayBrowser/#/R-DDI-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Dictyostelium discoideum 62077 R-DME-77325 https://reactome.org/PathwayBrowser/#/R-DME-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Drosophila melanogaster 62077 R-DME-77327 https://reactome.org/PathwayBrowser/#/R-DME-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 62077 R-DRE-77327 https://reactome.org/PathwayBrowser/#/R-DRE-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Danio rerio 62077 R-GGA-77327 https://reactome.org/PathwayBrowser/#/R-GGA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Gallus gallus 62077 R-HSA-77325 https://reactome.org/PathwayBrowser/#/R-HSA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA TAS Homo sapiens 62077 R-HSA-77327 https://reactome.org/PathwayBrowser/#/R-HSA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 TAS Homo sapiens 62077 R-MMU-77325 https://reactome.org/PathwayBrowser/#/R-MMU-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Mus musculus 62077 R-MMU-77327 https://reactome.org/PathwayBrowser/#/R-MMU-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Mus musculus 62077 R-RNO-77325 https://reactome.org/PathwayBrowser/#/R-RNO-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Rattus norvegicus 62077 R-RNO-77327 https://reactome.org/PathwayBrowser/#/R-RNO-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 62077 R-SSC-77325 https://reactome.org/PathwayBrowser/#/R-SSC-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Sus scrofa 62077 R-SSC-77327 https://reactome.org/PathwayBrowser/#/R-SSC-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Sus scrofa 62077 R-XTR-77325 https://reactome.org/PathwayBrowser/#/R-XTR-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Xenopus tropicalis 62077 R-XTR-77327 https://reactome.org/PathwayBrowser/#/R-XTR-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Xenopus tropicalis 62113 R-BTA-8850356 https://reactome.org/PathwayBrowser/#/R-BTA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Bos taurus 62113 R-GGA-8850356 https://reactome.org/PathwayBrowser/#/R-GGA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Gallus gallus 62113 R-HSA-8850356 https://reactome.org/PathwayBrowser/#/R-HSA-8850356 TCR binds microbial lipid-based antigen via CD1 TAS Homo sapiens 62113 R-SSC-8850356 https://reactome.org/PathwayBrowser/#/R-SSC-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Sus scrofa 62286 R-BTA-2509793 https://reactome.org/PathwayBrowser/#/R-BTA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Bos taurus 62286 R-CFA-2509793 https://reactome.org/PathwayBrowser/#/R-CFA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Canis familiaris 62286 R-DRE-2509793 https://reactome.org/PathwayBrowser/#/R-DRE-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Danio rerio 62286 R-HSA-2509793 https://reactome.org/PathwayBrowser/#/R-HSA-2509793 NUDT16 hydrolyses dIDP to dIMP TAS Homo sapiens 62286 R-MMU-2509793 https://reactome.org/PathwayBrowser/#/R-MMU-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Mus musculus 62286 R-RNO-2509793 https://reactome.org/PathwayBrowser/#/R-RNO-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Rattus norvegicus 62286 R-SSC-2509793 https://reactome.org/PathwayBrowser/#/R-SSC-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Sus scrofa 62286 R-XTR-2509793 https://reactome.org/PathwayBrowser/#/R-XTR-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Xenopus tropicalis 62384 R-BTA-8850356 https://reactome.org/PathwayBrowser/#/R-BTA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Bos taurus 62384 R-CFA-8850356 https://reactome.org/PathwayBrowser/#/R-CFA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Canis familiaris 62384 R-GGA-8850356 https://reactome.org/PathwayBrowser/#/R-GGA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Gallus gallus 62384 R-HSA-8850356 https://reactome.org/PathwayBrowser/#/R-HSA-8850356 TCR binds microbial lipid-based antigen via CD1 TAS Homo sapiens 62384 R-SSC-8850356 https://reactome.org/PathwayBrowser/#/R-SSC-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Sus scrofa 62579 R-HSA-1222325 https://reactome.org/PathwayBrowser/#/R-HSA-1222325 Carboxymycobactin and mycobactin exchange their iron load TAS Homo sapiens 62579 R-HSA-1222641 https://reactome.org/PathwayBrowser/#/R-HSA-1222641 Carboxymycobactin binds LTF:2xFe3+:2xCO3(2-) TAS Homo sapiens 62579 R-HSA-1222738 https://reactome.org/PathwayBrowser/#/R-HSA-1222738 Carboxymycobactin gets secreted TAS Homo sapiens 62579 R-HSA-8951549 https://reactome.org/PathwayBrowser/#/R-HSA-8951549 Carbocymycobactin binds Fe3+ from LTF:2xFe3+:2xCO3(2-) TAS Homo sapiens 62579 R-HSA-8951552 https://reactome.org/PathwayBrowser/#/R-HSA-8951552 LTF:2xCO3(2-) dissociates from Carbocymycobactin:Fe3+ TAS Homo sapiens 62620 R-BTA-77327 https://reactome.org/PathwayBrowser/#/R-BTA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Bos taurus 62620 R-BTA-77329 https://reactome.org/PathwayBrowser/#/R-BTA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Bos taurus 62620 R-CEL-77329 https://reactome.org/PathwayBrowser/#/R-CEL-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Caenorhabditis elegans 62620 R-CFA-77327 https://reactome.org/PathwayBrowser/#/R-CFA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Canis familiaris 62620 R-CFA-77329 https://reactome.org/PathwayBrowser/#/R-CFA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Canis familiaris 62620 R-DME-77327 https://reactome.org/PathwayBrowser/#/R-DME-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 62620 R-DME-77329 https://reactome.org/PathwayBrowser/#/R-DME-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Drosophila melanogaster 62620 R-DRE-77327 https://reactome.org/PathwayBrowser/#/R-DRE-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Danio rerio 62620 R-DRE-77329 https://reactome.org/PathwayBrowser/#/R-DRE-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Danio rerio 62620 R-GGA-77327 https://reactome.org/PathwayBrowser/#/R-GGA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Gallus gallus 62620 R-GGA-77329 https://reactome.org/PathwayBrowser/#/R-GGA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Gallus gallus 62620 R-HSA-77327 https://reactome.org/PathwayBrowser/#/R-HSA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 TAS Homo sapiens 62620 R-HSA-77329 https://reactome.org/PathwayBrowser/#/R-HSA-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA TAS Homo sapiens 62620 R-MMU-77327 https://reactome.org/PathwayBrowser/#/R-MMU-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Mus musculus 62620 R-MMU-77329 https://reactome.org/PathwayBrowser/#/R-MMU-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Mus musculus 62620 R-RNO-77327 https://reactome.org/PathwayBrowser/#/R-RNO-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 62620 R-RNO-77329 https://reactome.org/PathwayBrowser/#/R-RNO-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Rattus norvegicus 62620 R-SSC-77327 https://reactome.org/PathwayBrowser/#/R-SSC-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Sus scrofa 62620 R-SSC-77329 https://reactome.org/PathwayBrowser/#/R-SSC-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Sus scrofa 62620 R-XTR-77327 https://reactome.org/PathwayBrowser/#/R-XTR-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Xenopus tropicalis 62620 R-XTR-77329 https://reactome.org/PathwayBrowser/#/R-XTR-77329 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA IEA Xenopus tropicalis 62626 R-BTA-190182 https://reactome.org/PathwayBrowser/#/R-BTA-190182 UROD decarboxylates URO1 to COPRO1 IEA Bos taurus 62626 R-CFA-190182 https://reactome.org/PathwayBrowser/#/R-CFA-190182 UROD decarboxylates URO1 to COPRO1 IEA Canis familiaris 62626 R-DDI-190182 https://reactome.org/PathwayBrowser/#/R-DDI-190182 UROD decarboxylates URO1 to COPRO1 IEA Dictyostelium discoideum 62626 R-DME-190182 https://reactome.org/PathwayBrowser/#/R-DME-190182 UROD decarboxylates URO1 to COPRO1 IEA Drosophila melanogaster 62626 R-DRE-190182 https://reactome.org/PathwayBrowser/#/R-DRE-190182 UROD decarboxylates URO1 to COPRO1 IEA Danio rerio 62626 R-GGA-190182 https://reactome.org/PathwayBrowser/#/R-GGA-190182 UROD decarboxylates URO1 to COPRO1 IEA Gallus gallus 62626 R-GGA-421459 https://reactome.org/PathwayBrowser/#/R-GGA-421459 uroporphyrinogen I => coproporphyrinogen I + 4 CO2 IEA Gallus gallus 62626 R-GGA-421471 https://reactome.org/PathwayBrowser/#/R-GGA-421471 hydroxymethylbilane => uroporphyrinogen I + H2O IEA Gallus gallus 62626 R-HSA-190168 https://reactome.org/PathwayBrowser/#/R-HSA-190168 HMBL spontaneously transforms to URO1 TAS Homo sapiens 62626 R-HSA-190182 https://reactome.org/PathwayBrowser/#/R-HSA-190182 UROD decarboxylates URO1 to COPRO1 TAS Homo sapiens 62626 R-MMU-190182 https://reactome.org/PathwayBrowser/#/R-MMU-190182 UROD decarboxylates URO1 to COPRO1 IEA Mus musculus 62626 R-PFA-190182 https://reactome.org/PathwayBrowser/#/R-PFA-190182 UROD decarboxylates URO1 to COPRO1 IEA Plasmodium falciparum 62626 R-RNO-190182 https://reactome.org/PathwayBrowser/#/R-RNO-190182 UROD decarboxylates URO1 to COPRO1 IEA Rattus norvegicus 62626 R-SCE-190182 https://reactome.org/PathwayBrowser/#/R-SCE-190182 UROD decarboxylates URO1 to COPRO1 IEA Saccharomyces cerevisiae 62626 R-SPO-190182 https://reactome.org/PathwayBrowser/#/R-SPO-190182 UROD decarboxylates URO1 to COPRO1 IEA Schizosaccharomyces pombe 62626 R-SSC-190182 https://reactome.org/PathwayBrowser/#/R-SSC-190182 UROD decarboxylates URO1 to COPRO1 IEA Sus scrofa 62626 R-XTR-190182 https://reactome.org/PathwayBrowser/#/R-XTR-190182 UROD decarboxylates URO1 to COPRO1 IEA Xenopus tropicalis 62631 R-BTA-190182 https://reactome.org/PathwayBrowser/#/R-BTA-190182 UROD decarboxylates URO1 to COPRO1 IEA Bos taurus 62631 R-CFA-190182 https://reactome.org/PathwayBrowser/#/R-CFA-190182 UROD decarboxylates URO1 to COPRO1 IEA Canis familiaris 62631 R-DDI-190182 https://reactome.org/PathwayBrowser/#/R-DDI-190182 UROD decarboxylates URO1 to COPRO1 IEA Dictyostelium discoideum 62631 R-DME-190182 https://reactome.org/PathwayBrowser/#/R-DME-190182 UROD decarboxylates URO1 to COPRO1 IEA Drosophila melanogaster 62631 R-DRE-190182 https://reactome.org/PathwayBrowser/#/R-DRE-190182 UROD decarboxylates URO1 to COPRO1 IEA Danio rerio 62631 R-GGA-190182 https://reactome.org/PathwayBrowser/#/R-GGA-190182 UROD decarboxylates URO1 to COPRO1 IEA Gallus gallus 62631 R-GGA-421459 https://reactome.org/PathwayBrowser/#/R-GGA-421459 uroporphyrinogen I => coproporphyrinogen I + 4 CO2 IEA Gallus gallus 62631 R-HSA-190182 https://reactome.org/PathwayBrowser/#/R-HSA-190182 UROD decarboxylates URO1 to COPRO1 TAS Homo sapiens 62631 R-MMU-190182 https://reactome.org/PathwayBrowser/#/R-MMU-190182 UROD decarboxylates URO1 to COPRO1 IEA Mus musculus 62631 R-PFA-190182 https://reactome.org/PathwayBrowser/#/R-PFA-190182 UROD decarboxylates URO1 to COPRO1 IEA Plasmodium falciparum 62631 R-RNO-190182 https://reactome.org/PathwayBrowser/#/R-RNO-190182 UROD decarboxylates URO1 to COPRO1 IEA Rattus norvegicus 62631 R-SCE-190182 https://reactome.org/PathwayBrowser/#/R-SCE-190182 UROD decarboxylates URO1 to COPRO1 IEA Saccharomyces cerevisiae 62631 R-SPO-190182 https://reactome.org/PathwayBrowser/#/R-SPO-190182 UROD decarboxylates URO1 to COPRO1 IEA Schizosaccharomyces pombe 62631 R-SSC-190182 https://reactome.org/PathwayBrowser/#/R-SSC-190182 UROD decarboxylates URO1 to COPRO1 IEA Sus scrofa 62631 R-XTR-190182 https://reactome.org/PathwayBrowser/#/R-XTR-190182 UROD decarboxylates URO1 to COPRO1 IEA Xenopus tropicalis 62634 R-BTA-4084980 https://reactome.org/PathwayBrowser/#/R-BTA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Bos taurus 62634 R-BTA-4084999 https://reactome.org/PathwayBrowser/#/R-BTA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 62634 R-BTA-4085029 https://reactome.org/PathwayBrowser/#/R-BTA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 62634 R-BTA-9638120 https://reactome.org/PathwayBrowser/#/R-BTA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 62634 R-CFA-4084980 https://reactome.org/PathwayBrowser/#/R-CFA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Canis familiaris 62634 R-CFA-4084999 https://reactome.org/PathwayBrowser/#/R-CFA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 62634 R-CFA-4085029 https://reactome.org/PathwayBrowser/#/R-CFA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 62634 R-CFA-9638120 https://reactome.org/PathwayBrowser/#/R-CFA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 62634 R-DRE-4084980 https://reactome.org/PathwayBrowser/#/R-DRE-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Danio rerio 62634 R-DRE-4085029 https://reactome.org/PathwayBrowser/#/R-DRE-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 62634 R-GGA-4084980 https://reactome.org/PathwayBrowser/#/R-GGA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Gallus gallus 62634 R-GGA-4085029 https://reactome.org/PathwayBrowser/#/R-GGA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 62634 R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus 62634 R-HSA-4084980 https://reactome.org/PathwayBrowser/#/R-HSA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) TAS Homo sapiens 62634 R-HSA-4084999 https://reactome.org/PathwayBrowser/#/R-HSA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 62634 R-HSA-4085029 https://reactome.org/PathwayBrowser/#/R-HSA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 62634 R-HSA-4088205 https://reactome.org/PathwayBrowser/#/R-HSA-4088205 Plasma membrane glycoconjugates translocate to the cytosol TAS Homo sapiens 62634 R-HSA-4088207 https://reactome.org/PathwayBrowser/#/R-HSA-4088207 Golgi lumen glycoconjugates translocate to the plasma membrane TAS Homo sapiens 62634 R-HSA-4088210 https://reactome.org/PathwayBrowser/#/R-HSA-4088210 Cytosolic glycoconjugates translocate to the lysosome TAS Homo sapiens 62634 R-HSA-4341669 https://reactome.org/PathwayBrowser/#/R-HSA-4341669 Defective NEU1 does not hydrolyse Neu5Ac from glycoconjugates TAS Homo sapiens 62634 R-HSA-9638120 https://reactome.org/PathwayBrowser/#/R-HSA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 62634 R-MMU-4084980 https://reactome.org/PathwayBrowser/#/R-MMU-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Mus musculus 62634 R-MMU-4084999 https://reactome.org/PathwayBrowser/#/R-MMU-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 62634 R-MMU-4085029 https://reactome.org/PathwayBrowser/#/R-MMU-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 62634 R-MMU-9638120 https://reactome.org/PathwayBrowser/#/R-MMU-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 62634 R-RNO-4084980 https://reactome.org/PathwayBrowser/#/R-RNO-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Rattus norvegicus 62634 R-RNO-4084999 https://reactome.org/PathwayBrowser/#/R-RNO-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 62634 R-RNO-4085029 https://reactome.org/PathwayBrowser/#/R-RNO-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 62634 R-RNO-9638120 https://reactome.org/PathwayBrowser/#/R-RNO-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 62634 R-SSC-4084980 https://reactome.org/PathwayBrowser/#/R-SSC-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Sus scrofa 62634 R-SSC-4084999 https://reactome.org/PathwayBrowser/#/R-SSC-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 62634 R-SSC-4085029 https://reactome.org/PathwayBrowser/#/R-SSC-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 62634 R-SSC-9638120 https://reactome.org/PathwayBrowser/#/R-SSC-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 62634 R-XTR-4084980 https://reactome.org/PathwayBrowser/#/R-XTR-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Xenopus tropicalis 62634 R-XTR-4084999 https://reactome.org/PathwayBrowser/#/R-XTR-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 62634 R-XTR-4085029 https://reactome.org/PathwayBrowser/#/R-XTR-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 62634 R-XTR-9638120 https://reactome.org/PathwayBrowser/#/R-XTR-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 62637 R-BTA-6784399 https://reactome.org/PathwayBrowser/#/R-BTA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Bos taurus 62637 R-CFA-6784399 https://reactome.org/PathwayBrowser/#/R-CFA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Canis familiaris 62637 R-DRE-6784399 https://reactome.org/PathwayBrowser/#/R-DRE-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Danio rerio 62637 R-GGA-6784399 https://reactome.org/PathwayBrowser/#/R-GGA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Gallus gallus 62637 R-HSA-6784399 https://reactome.org/PathwayBrowser/#/R-HSA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate TAS Homo sapiens 62637 R-HSA-6784402 https://reactome.org/PathwayBrowser/#/R-HSA-6784402 Spontaneous hydrolysis of 1-pyrroline-3-hydroxy-5-carboxylate to 4-OH-L-glutamate semialdehyde TAS Homo sapiens 62637 R-MMU-6784399 https://reactome.org/PathwayBrowser/#/R-MMU-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Mus musculus 62637 R-RNO-6784399 https://reactome.org/PathwayBrowser/#/R-RNO-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Rattus norvegicus 62637 R-SSC-6784399 https://reactome.org/PathwayBrowser/#/R-SSC-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Sus scrofa 62637 R-XTR-6784399 https://reactome.org/PathwayBrowser/#/R-XTR-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate IEA Xenopus tropicalis 62643 R-BTA-1467269 https://reactome.org/PathwayBrowser/#/R-BTA-1467269 Beta-defensins bind microbial membranes causing disruption IEA Bos taurus 62643 R-BTA-6801762 https://reactome.org/PathwayBrowser/#/R-BTA-6801762 REG3A oligomerize to form a pore complex IEA Bos taurus 62643 R-BTA-6801776 https://reactome.org/PathwayBrowser/#/R-BTA-6801776 REG3A binds bacterial phospholipids IEA Bos taurus 62643 R-BTA-6806732 https://reactome.org/PathwayBrowser/#/R-BTA-6806732 GNLY binds the bacterial cell surface IEA Bos taurus 62643 R-BTA-6807144 https://reactome.org/PathwayBrowser/#/R-BTA-6807144 HTN1,HTN3 or HTN5 binds the bacterial anionic surface IEA Bos taurus 62643 R-BTA-6807578 https://reactome.org/PathwayBrowser/#/R-BTA-6807578 GNLY binds the bacterial cell surface in the phagosome IEA Bos taurus 62643 R-BTA-6808566 https://reactome.org/PathwayBrowser/#/R-BTA-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Bos taurus 62643 R-BTA-6813626 https://reactome.org/PathwayBrowser/#/R-BTA-6813626 LEAP2 binds bacteria IEA Bos taurus 62643 R-BTA-8862771 https://reactome.org/PathwayBrowser/#/R-BTA-8862771 PLA2G2A binds bacterial phospholipids IEA Bos taurus 62643 R-BTA-8948027 https://reactome.org/PathwayBrowser/#/R-BTA-8948027 RNASEs bind bacterial phospholipids IEA Bos taurus 62643 R-CEL-6801762 https://reactome.org/PathwayBrowser/#/R-CEL-6801762 REG3A oligomerize to form a pore complex IEA Caenorhabditis elegans 62643 R-CEL-6801776 https://reactome.org/PathwayBrowser/#/R-CEL-6801776 REG3A binds bacterial phospholipids IEA Caenorhabditis elegans 62643 R-CEL-8862771 https://reactome.org/PathwayBrowser/#/R-CEL-8862771 PLA2G2A binds bacterial phospholipids IEA Caenorhabditis elegans 62643 R-CFA-6801762 https://reactome.org/PathwayBrowser/#/R-CFA-6801762 REG3A oligomerize to form a pore complex IEA Canis familiaris 62643 R-CFA-6801776 https://reactome.org/PathwayBrowser/#/R-CFA-6801776 REG3A binds bacterial phospholipids IEA Canis familiaris 62643 R-CFA-6806732 https://reactome.org/PathwayBrowser/#/R-CFA-6806732 GNLY binds the bacterial cell surface IEA Canis familiaris 62643 R-CFA-6807578 https://reactome.org/PathwayBrowser/#/R-CFA-6807578 GNLY binds the bacterial cell surface in the phagosome IEA Canis familiaris 62643 R-CFA-6808566 https://reactome.org/PathwayBrowser/#/R-CFA-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Canis familiaris 62643 R-CFA-6813626 https://reactome.org/PathwayBrowser/#/R-CFA-6813626 LEAP2 binds bacteria IEA Canis familiaris 62643 R-DME-6801762 https://reactome.org/PathwayBrowser/#/R-DME-6801762 REG3A oligomerize to form a pore complex IEA Drosophila melanogaster 62643 R-DME-6801776 https://reactome.org/PathwayBrowser/#/R-DME-6801776 REG3A binds bacterial phospholipids IEA Drosophila melanogaster 62643 R-DME-8862771 https://reactome.org/PathwayBrowser/#/R-DME-8862771 PLA2G2A binds bacterial phospholipids IEA Drosophila melanogaster 62643 R-DRE-6806732 https://reactome.org/PathwayBrowser/#/R-DRE-6806732 GNLY binds the bacterial cell surface IEA Danio rerio 62643 R-DRE-6807578 https://reactome.org/PathwayBrowser/#/R-DRE-6807578 GNLY binds the bacterial cell surface in the phagosome IEA Danio rerio 62643 R-DRE-6813626 https://reactome.org/PathwayBrowser/#/R-DRE-6813626 LEAP2 binds bacteria IEA Danio rerio 62643 R-DRE-8948027 https://reactome.org/PathwayBrowser/#/R-DRE-8948027 RNASEs bind bacterial phospholipids IEA Danio rerio 62643 R-GGA-1467269 https://reactome.org/PathwayBrowser/#/R-GGA-1467269 Beta-defensins bind microbial membranes causing disruption IEA Gallus gallus 62643 R-GGA-6806732 https://reactome.org/PathwayBrowser/#/R-GGA-6806732 GNLY binds the bacterial cell surface IEA Gallus gallus 62643 R-GGA-6807578 https://reactome.org/PathwayBrowser/#/R-GGA-6807578 GNLY binds the bacterial cell surface in the phagosome IEA Gallus gallus 62643 R-GGA-6808566 https://reactome.org/PathwayBrowser/#/R-GGA-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Gallus gallus 62643 R-GGA-6813626 https://reactome.org/PathwayBrowser/#/R-GGA-6813626 LEAP2 binds bacteria IEA Gallus gallus 62643 R-GGA-8862771 https://reactome.org/PathwayBrowser/#/R-GGA-8862771 PLA2G2A binds bacterial phospholipids IEA Gallus gallus 62643 R-GGA-8948027 https://reactome.org/PathwayBrowser/#/R-GGA-8948027 RNASEs bind bacterial phospholipids IEA Gallus gallus 62643 R-HSA-1461971 https://reactome.org/PathwayBrowser/#/R-HSA-1461971 Alpha-defensin dimers adsorb onto microbial membrane anionic phospholipids TAS Homo sapiens 62643 R-HSA-1461982 https://reactome.org/PathwayBrowser/#/R-HSA-1461982 Alpha-defensin dimers multimerize to form a pore complex TAS Homo sapiens 62643 R-HSA-1467269 https://reactome.org/PathwayBrowser/#/R-HSA-1467269 Beta-defensins bind microbial membranes causing disruption TAS Homo sapiens 62643 R-HSA-6801762 https://reactome.org/PathwayBrowser/#/R-HSA-6801762 REG3A oligomerize to form a pore complex TAS Homo sapiens 62643 R-HSA-6801776 https://reactome.org/PathwayBrowser/#/R-HSA-6801776 REG3A binds bacterial phospholipids TAS Homo sapiens 62643 R-HSA-6803047 https://reactome.org/PathwayBrowser/#/R-HSA-6803047 DCD peptide binds bacterial membrane phospholipids TAS Homo sapiens 62643 R-HSA-6803104 https://reactome.org/PathwayBrowser/#/R-HSA-6803104 DCD forms oligomeric complex TAS Homo sapiens 62643 R-HSA-6806732 https://reactome.org/PathwayBrowser/#/R-HSA-6806732 GNLY binds the bacterial cell surface TAS Homo sapiens 62643 R-HSA-6807144 https://reactome.org/PathwayBrowser/#/R-HSA-6807144 HTN1,HTN3 or HTN5 binds the bacterial anionic surface TAS Homo sapiens 62643 R-HSA-6807578 https://reactome.org/PathwayBrowser/#/R-HSA-6807578 GNLY binds the bacterial cell surface in the phagosome TAS Homo sapiens 62643 R-HSA-6808566 https://reactome.org/PathwayBrowser/#/R-HSA-6808566 CHGA-derived peptide binds the bacterial cell surface TAS Homo sapiens 62643 R-HSA-6813626 https://reactome.org/PathwayBrowser/#/R-HSA-6813626 LEAP2 binds bacteria TAS Homo sapiens 62643 R-HSA-8862771 https://reactome.org/PathwayBrowser/#/R-HSA-8862771 PLA2G2A binds bacterial phospholipids TAS Homo sapiens 62643 R-HSA-8948027 https://reactome.org/PathwayBrowser/#/R-HSA-8948027 RNASEs bind bacterial phospholipids TAS Homo sapiens 62643 R-MMU-1461971 https://reactome.org/PathwayBrowser/#/R-MMU-1461971 Alpha-defensin dimers adsorb onto microbial membrane anionic phospholipids IEA Mus musculus 62643 R-MMU-1461982 https://reactome.org/PathwayBrowser/#/R-MMU-1461982 Alpha-defensin dimers multimerize to form a pore complex IEA Mus musculus 62643 R-MMU-1467269 https://reactome.org/PathwayBrowser/#/R-MMU-1467269 Beta-defensins bind microbial membranes causing disruption IEA Mus musculus 62643 R-MMU-6801762 https://reactome.org/PathwayBrowser/#/R-MMU-6801762 REG3A oligomerize to form a pore complex IEA Mus musculus 62643 R-MMU-6801776 https://reactome.org/PathwayBrowser/#/R-MMU-6801776 REG3A binds bacterial phospholipids IEA Mus musculus 62643 R-MMU-6808566 https://reactome.org/PathwayBrowser/#/R-MMU-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Mus musculus 62643 R-MMU-6813626 https://reactome.org/PathwayBrowser/#/R-MMU-6813626 LEAP2 binds bacteria IEA Mus musculus 62643 R-MMU-8862771 https://reactome.org/PathwayBrowser/#/R-MMU-8862771 PLA2G2A binds bacterial phospholipids IEA Mus musculus 62643 R-MMU-8948027 https://reactome.org/PathwayBrowser/#/R-MMU-8948027 RNASEs bind bacterial phospholipids IEA Mus musculus 62643 R-RNO-1461971 https://reactome.org/PathwayBrowser/#/R-RNO-1461971 Alpha-defensin dimers adsorb onto microbial membrane anionic phospholipids IEA Rattus norvegicus 62643 R-RNO-1461982 https://reactome.org/PathwayBrowser/#/R-RNO-1461982 Alpha-defensin dimers multimerize to form a pore complex IEA Rattus norvegicus 62643 R-RNO-1467269 https://reactome.org/PathwayBrowser/#/R-RNO-1467269 Beta-defensins bind microbial membranes causing disruption IEA Rattus norvegicus 62643 R-RNO-6801762 https://reactome.org/PathwayBrowser/#/R-RNO-6801762 REG3A oligomerize to form a pore complex IEA Rattus norvegicus 62643 R-RNO-6801776 https://reactome.org/PathwayBrowser/#/R-RNO-6801776 REG3A binds bacterial phospholipids IEA Rattus norvegicus 62643 R-RNO-6807144 https://reactome.org/PathwayBrowser/#/R-RNO-6807144 HTN1,HTN3 or HTN5 binds the bacterial anionic surface IEA Rattus norvegicus 62643 R-RNO-6808566 https://reactome.org/PathwayBrowser/#/R-RNO-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Rattus norvegicus 62643 R-RNO-6813626 https://reactome.org/PathwayBrowser/#/R-RNO-6813626 LEAP2 binds bacteria IEA Rattus norvegicus 62643 R-RNO-8862771 https://reactome.org/PathwayBrowser/#/R-RNO-8862771 PLA2G2A binds bacterial phospholipids IEA Rattus norvegicus 62643 R-RNO-8948027 https://reactome.org/PathwayBrowser/#/R-RNO-8948027 RNASEs bind bacterial phospholipids IEA Rattus norvegicus 62643 R-SSC-1467269 https://reactome.org/PathwayBrowser/#/R-SSC-1467269 Beta-defensins bind microbial membranes causing disruption IEA Sus scrofa 62643 R-SSC-6801762 https://reactome.org/PathwayBrowser/#/R-SSC-6801762 REG3A oligomerize to form a pore complex IEA Sus scrofa 62643 R-SSC-6801776 https://reactome.org/PathwayBrowser/#/R-SSC-6801776 REG3A binds bacterial phospholipids IEA Sus scrofa 62643 R-SSC-6806732 https://reactome.org/PathwayBrowser/#/R-SSC-6806732 GNLY binds the bacterial cell surface IEA Sus scrofa 62643 R-SSC-6807578 https://reactome.org/PathwayBrowser/#/R-SSC-6807578 GNLY binds the bacterial cell surface in the phagosome IEA Sus scrofa 62643 R-SSC-6808566 https://reactome.org/PathwayBrowser/#/R-SSC-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Sus scrofa 62643 R-SSC-6813626 https://reactome.org/PathwayBrowser/#/R-SSC-6813626 LEAP2 binds bacteria IEA Sus scrofa 62643 R-SSC-8862771 https://reactome.org/PathwayBrowser/#/R-SSC-8862771 PLA2G2A binds bacterial phospholipids IEA Sus scrofa 62643 R-SSC-8948027 https://reactome.org/PathwayBrowser/#/R-SSC-8948027 RNASEs bind bacterial phospholipids IEA Sus scrofa 62643 R-XTR-6801762 https://reactome.org/PathwayBrowser/#/R-XTR-6801762 REG3A oligomerize to form a pore complex IEA Xenopus tropicalis 62643 R-XTR-6801776 https://reactome.org/PathwayBrowser/#/R-XTR-6801776 REG3A binds bacterial phospholipids IEA Xenopus tropicalis 62643 R-XTR-6808566 https://reactome.org/PathwayBrowser/#/R-XTR-6808566 CHGA-derived peptide binds the bacterial cell surface IEA Xenopus tropicalis 62643 R-XTR-8862771 https://reactome.org/PathwayBrowser/#/R-XTR-8862771 PLA2G2A binds bacterial phospholipids IEA Xenopus tropicalis 62647 R-BTA-9605700 https://reactome.org/PathwayBrowser/#/R-BTA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Bos taurus 62647 R-CFA-9605700 https://reactome.org/PathwayBrowser/#/R-CFA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Canis familiaris 62647 R-HSA-9605700 https://reactome.org/PathwayBrowser/#/R-HSA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda TAS Homo sapiens 62647 R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 62647 R-MMU-9605700 https://reactome.org/PathwayBrowser/#/R-MMU-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Mus musculus 62647 R-RNO-9605700 https://reactome.org/PathwayBrowser/#/R-RNO-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Rattus norvegicus 62647 R-SSC-9605700 https://reactome.org/PathwayBrowser/#/R-SSC-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Sus scrofa 62647 R-XTR-9605700 https://reactome.org/PathwayBrowser/#/R-XTR-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Xenopus tropicalis 62726 R-HSA-8942075 https://reactome.org/PathwayBrowser/#/R-HSA-8942075 Peroxynitrite and carbon dioxide react to nitrosoperoxycarbonate TAS Homo sapiens 62746 R-BTA-1482626 https://reactome.org/PathwayBrowser/#/R-BTA-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Bos taurus 62746 R-BTA-1482932 https://reactome.org/PathwayBrowser/#/R-BTA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Bos taurus 62746 R-CEL-1482626 https://reactome.org/PathwayBrowser/#/R-CEL-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Caenorhabditis elegans 62746 R-CFA-1482626 https://reactome.org/PathwayBrowser/#/R-CFA-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Canis familiaris 62746 R-CFA-1482932 https://reactome.org/PathwayBrowser/#/R-CFA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Canis familiaris 62746 R-DDI-1482626 https://reactome.org/PathwayBrowser/#/R-DDI-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Dictyostelium discoideum 62746 R-DME-1482626 https://reactome.org/PathwayBrowser/#/R-DME-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Drosophila melanogaster 62746 R-DRE-1482626 https://reactome.org/PathwayBrowser/#/R-DRE-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Danio rerio 62746 R-GGA-1482932 https://reactome.org/PathwayBrowser/#/R-GGA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Gallus gallus 62746 R-HSA-1482626 https://reactome.org/PathwayBrowser/#/R-HSA-1482626 2-acyl LPI is acylated to PI by MBOAT7 TAS Homo sapiens 62746 R-HSA-1482932 https://reactome.org/PathwayBrowser/#/R-HSA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] TAS Homo sapiens 62746 R-MMU-1482626 https://reactome.org/PathwayBrowser/#/R-MMU-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Mus musculus 62746 R-MMU-1482932 https://reactome.org/PathwayBrowser/#/R-MMU-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Mus musculus 62746 R-RNO-1482932 https://reactome.org/PathwayBrowser/#/R-RNO-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Rattus norvegicus 62746 R-SCE-1482626 https://reactome.org/PathwayBrowser/#/R-SCE-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Saccharomyces cerevisiae 62746 R-SCE-1482932 https://reactome.org/PathwayBrowser/#/R-SCE-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Saccharomyces cerevisiae 62746 R-SPO-1482626 https://reactome.org/PathwayBrowser/#/R-SPO-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Schizosaccharomyces pombe 62746 R-SPO-1482932 https://reactome.org/PathwayBrowser/#/R-SPO-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Schizosaccharomyces pombe 62746 R-SSC-1482626 https://reactome.org/PathwayBrowser/#/R-SSC-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Sus scrofa 62746 R-SSC-1482932 https://reactome.org/PathwayBrowser/#/R-SSC-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Sus scrofa 62746 R-XTR-1482626 https://reactome.org/PathwayBrowser/#/R-XTR-1482626 2-acyl LPI is acylated to PI by MBOAT7 IEA Xenopus tropicalis 62747 R-BTA-1482539 https://reactome.org/PathwayBrowser/#/R-BTA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Bos taurus 62747 R-BTA-1482689 https://reactome.org/PathwayBrowser/#/R-BTA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Bos taurus 62747 R-BTA-1482745 https://reactome.org/PathwayBrowser/#/R-BTA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Bos taurus 62747 R-BTA-1482900 https://reactome.org/PathwayBrowser/#/R-BTA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Bos taurus 62747 R-BTA-1482907 https://reactome.org/PathwayBrowser/#/R-BTA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Bos taurus 62747 R-BTA-1602368 https://reactome.org/PathwayBrowser/#/R-BTA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Bos taurus 62747 R-CEL-1482539 https://reactome.org/PathwayBrowser/#/R-CEL-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Caenorhabditis elegans 62747 R-CEL-1482689 https://reactome.org/PathwayBrowser/#/R-CEL-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Caenorhabditis elegans 62747 R-CEL-1482900 https://reactome.org/PathwayBrowser/#/R-CEL-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Caenorhabditis elegans 62747 R-CEL-1482907 https://reactome.org/PathwayBrowser/#/R-CEL-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Caenorhabditis elegans 62747 R-CEL-1602368 https://reactome.org/PathwayBrowser/#/R-CEL-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Caenorhabditis elegans 62747 R-CFA-1482539 https://reactome.org/PathwayBrowser/#/R-CFA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Canis familiaris 62747 R-CFA-1482745 https://reactome.org/PathwayBrowser/#/R-CFA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Canis familiaris 62747 R-CFA-1482900 https://reactome.org/PathwayBrowser/#/R-CFA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Canis familiaris 62747 R-CFA-1602368 https://reactome.org/PathwayBrowser/#/R-CFA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Canis familiaris 62747 R-DDI-1482539 https://reactome.org/PathwayBrowser/#/R-DDI-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Dictyostelium discoideum 62747 R-DME-1482539 https://reactome.org/PathwayBrowser/#/R-DME-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Drosophila melanogaster 62747 R-DME-1482689 https://reactome.org/PathwayBrowser/#/R-DME-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Drosophila melanogaster 62747 R-DME-1482900 https://reactome.org/PathwayBrowser/#/R-DME-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Drosophila melanogaster 62747 R-DME-1482907 https://reactome.org/PathwayBrowser/#/R-DME-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Drosophila melanogaster 62747 R-DME-1602368 https://reactome.org/PathwayBrowser/#/R-DME-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Drosophila melanogaster 62747 R-DRE-1482539 https://reactome.org/PathwayBrowser/#/R-DRE-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Danio rerio 62747 R-DRE-1482689 https://reactome.org/PathwayBrowser/#/R-DRE-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Danio rerio 62747 R-DRE-1482900 https://reactome.org/PathwayBrowser/#/R-DRE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Danio rerio 62747 R-DRE-1602368 https://reactome.org/PathwayBrowser/#/R-DRE-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Danio rerio 62747 R-GGA-1482539 https://reactome.org/PathwayBrowser/#/R-GGA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Gallus gallus 62747 R-GGA-1482689 https://reactome.org/PathwayBrowser/#/R-GGA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Gallus gallus 62747 R-GGA-1482745 https://reactome.org/PathwayBrowser/#/R-GGA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Gallus gallus 62747 R-GGA-1482900 https://reactome.org/PathwayBrowser/#/R-GGA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Gallus gallus 62747 R-GGA-1482907 https://reactome.org/PathwayBrowser/#/R-GGA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Gallus gallus 62747 R-GGA-1602368 https://reactome.org/PathwayBrowser/#/R-GGA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Gallus gallus 62747 R-HSA-1482539 https://reactome.org/PathwayBrowser/#/R-HSA-1482539 1-acyl LPG is acylated to PG by LPGAT TAS Homo sapiens 62747 R-HSA-1482689 https://reactome.org/PathwayBrowser/#/R-HSA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) TAS Homo sapiens 62747 R-HSA-1482745 https://reactome.org/PathwayBrowser/#/R-HSA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) TAS Homo sapiens 62747 R-HSA-1482900 https://reactome.org/PathwayBrowser/#/R-HSA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] TAS Homo sapiens 62747 R-HSA-1482907 https://reactome.org/PathwayBrowser/#/R-HSA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A TAS Homo sapiens 62747 R-HSA-1602368 https://reactome.org/PathwayBrowser/#/R-HSA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] TAS Homo sapiens 62747 R-MMU-1482539 https://reactome.org/PathwayBrowser/#/R-MMU-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Mus musculus 62747 R-MMU-1482689 https://reactome.org/PathwayBrowser/#/R-MMU-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Mus musculus 62747 R-MMU-1482745 https://reactome.org/PathwayBrowser/#/R-MMU-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Mus musculus 62747 R-MMU-1482900 https://reactome.org/PathwayBrowser/#/R-MMU-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Mus musculus 62747 R-MMU-1482907 https://reactome.org/PathwayBrowser/#/R-MMU-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Mus musculus 62747 R-MMU-1602368 https://reactome.org/PathwayBrowser/#/R-MMU-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Mus musculus 62747 R-PFA-1482539 https://reactome.org/PathwayBrowser/#/R-PFA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Plasmodium falciparum 62747 R-RNO-1482539 https://reactome.org/PathwayBrowser/#/R-RNO-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Rattus norvegicus 62747 R-RNO-1482689 https://reactome.org/PathwayBrowser/#/R-RNO-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Rattus norvegicus 62747 R-RNO-1482745 https://reactome.org/PathwayBrowser/#/R-RNO-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Rattus norvegicus 62747 R-RNO-1482900 https://reactome.org/PathwayBrowser/#/R-RNO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Rattus norvegicus 62747 R-RNO-1482907 https://reactome.org/PathwayBrowser/#/R-RNO-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Rattus norvegicus 62747 R-RNO-1602368 https://reactome.org/PathwayBrowser/#/R-RNO-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Rattus norvegicus 62747 R-SCE-1482539 https://reactome.org/PathwayBrowser/#/R-SCE-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Saccharomyces cerevisiae 62747 R-SCE-1482689 https://reactome.org/PathwayBrowser/#/R-SCE-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Saccharomyces cerevisiae 62747 R-SCE-1482745 https://reactome.org/PathwayBrowser/#/R-SCE-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Saccharomyces cerevisiae 62747 R-SCE-1482900 https://reactome.org/PathwayBrowser/#/R-SCE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Saccharomyces cerevisiae 62747 R-SPO-1482539 https://reactome.org/PathwayBrowser/#/R-SPO-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Schizosaccharomyces pombe 62747 R-SPO-1482689 https://reactome.org/PathwayBrowser/#/R-SPO-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Schizosaccharomyces pombe 62747 R-SPO-1482745 https://reactome.org/PathwayBrowser/#/R-SPO-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Schizosaccharomyces pombe 62747 R-SPO-1482900 https://reactome.org/PathwayBrowser/#/R-SPO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Schizosaccharomyces pombe 62747 R-SSC-1482539 https://reactome.org/PathwayBrowser/#/R-SSC-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa 62747 R-SSC-1482689 https://reactome.org/PathwayBrowser/#/R-SSC-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Sus scrofa 62747 R-SSC-1482745 https://reactome.org/PathwayBrowser/#/R-SSC-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Sus scrofa 62747 R-SSC-1482900 https://reactome.org/PathwayBrowser/#/R-SSC-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Sus scrofa 62747 R-SSC-1482907 https://reactome.org/PathwayBrowser/#/R-SSC-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Sus scrofa 62747 R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa 62747 R-XTR-1482539 https://reactome.org/PathwayBrowser/#/R-XTR-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Xenopus tropicalis 62747 R-XTR-1482745 https://reactome.org/PathwayBrowser/#/R-XTR-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Xenopus tropicalis 62747 R-XTR-1482900 https://reactome.org/PathwayBrowser/#/R-XTR-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Xenopus tropicalis 62747 R-XTR-1482907 https://reactome.org/PathwayBrowser/#/R-XTR-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Xenopus tropicalis 62747 R-XTR-1602368 https://reactome.org/PathwayBrowser/#/R-XTR-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Xenopus tropicalis 62772 R-HSA-1497824 https://reactome.org/PathwayBrowser/#/R-HSA-1497824 BH4 is oxidised to the BH3 radical during the eNOS catalytic cycle TAS Homo sapiens 62772 R-HSA-1497855 https://reactome.org/PathwayBrowser/#/R-HSA-1497855 Ascorbate can reduce the BH3 radical back to BH4 TAS Homo sapiens 62772 R-HSA-1497863 https://reactome.org/PathwayBrowser/#/R-HSA-1497863 The BH3 radical can decay to dihydrobiopterin (BH2) TAS Homo sapiens 62772 R-HSA-1497866 https://reactome.org/PathwayBrowser/#/R-HSA-1497866 Peroxynitrite can oxidise BH4 to the BH3 radical TAS Homo sapiens 62772 R-HSA-1497883 https://reactome.org/PathwayBrowser/#/R-HSA-1497883 Ferrous iron reduces the BH3 radical back to BH4 TAS Homo sapiens 62793 R-BTA-2162193 https://reactome.org/PathwayBrowser/#/R-BTA-2162193 COQ3 methylates DHDB IEA Bos taurus 62793 R-CEL-2162193 https://reactome.org/PathwayBrowser/#/R-CEL-2162193 COQ3 methylates DHDB IEA Caenorhabditis elegans 62793 R-CFA-2162193 https://reactome.org/PathwayBrowser/#/R-CFA-2162193 COQ3 methylates DHDB IEA Canis familiaris 62793 R-DDI-2162193 https://reactome.org/PathwayBrowser/#/R-DDI-2162193 COQ3 methylates DHDB IEA Dictyostelium discoideum 62793 R-DME-2162193 https://reactome.org/PathwayBrowser/#/R-DME-2162193 COQ3 methylates DHDB IEA Drosophila melanogaster 62793 R-DRE-2162193 https://reactome.org/PathwayBrowser/#/R-DRE-2162193 COQ3 methylates DHDB IEA Danio rerio 62793 R-GGA-2162193 https://reactome.org/PathwayBrowser/#/R-GGA-2162193 COQ3 methylates DHDB IEA Gallus gallus 62793 R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB IEA Homo sapiens 62793 R-HSA-2162193 https://reactome.org/PathwayBrowser/#/R-HSA-2162193 COQ3 methylates DHDB TAS Homo sapiens 62793 R-MMU-2162193 https://reactome.org/PathwayBrowser/#/R-MMU-2162193 COQ3 methylates DHDB IEA Mus musculus 62793 R-RNO-2162193 https://reactome.org/PathwayBrowser/#/R-RNO-2162193 COQ3 methylates DHDB IEA Rattus norvegicus 62793 R-SCE-2162193 https://reactome.org/PathwayBrowser/#/R-SCE-2162193 COQ3 methylates DHDB IEA Saccharomyces cerevisiae 62793 R-SPO-2162193 https://reactome.org/PathwayBrowser/#/R-SPO-2162193 COQ3 methylates DHDB IEA Schizosaccharomyces pombe 62793 R-SSC-2162193 https://reactome.org/PathwayBrowser/#/R-SSC-2162193 COQ3 methylates DHDB IEA Sus scrofa 62793 R-XTR-2162193 https://reactome.org/PathwayBrowser/#/R-XTR-2162193 COQ3 methylates DHDB IEA Xenopus tropicalis 62796 R-BTA-2162193 https://reactome.org/PathwayBrowser/#/R-BTA-2162193 COQ3 methylates DHDB IEA Bos taurus 62796 R-CEL-2162193 https://reactome.org/PathwayBrowser/#/R-CEL-2162193 COQ3 methylates DHDB IEA Caenorhabditis elegans 62796 R-CFA-2162193 https://reactome.org/PathwayBrowser/#/R-CFA-2162193 COQ3 methylates DHDB IEA Canis familiaris 62796 R-DDI-2162193 https://reactome.org/PathwayBrowser/#/R-DDI-2162193 COQ3 methylates DHDB IEA Dictyostelium discoideum 62796 R-DME-2162193 https://reactome.org/PathwayBrowser/#/R-DME-2162193 COQ3 methylates DHDB IEA Drosophila melanogaster 62796 R-DRE-2162193 https://reactome.org/PathwayBrowser/#/R-DRE-2162193 COQ3 methylates DHDB IEA Danio rerio 62796 R-GGA-2162193 https://reactome.org/PathwayBrowser/#/R-GGA-2162193 COQ3 methylates DHDB IEA Gallus gallus 62796 R-HSA-2162193 https://reactome.org/PathwayBrowser/#/R-HSA-2162193 COQ3 methylates DHDB TAS Homo sapiens 62796 R-HSA-2162195 https://reactome.org/PathwayBrowser/#/R-HSA-2162195 Unknown enzyme decarboxylates MHDB IEA Homo sapiens 62796 R-MMU-2162193 https://reactome.org/PathwayBrowser/#/R-MMU-2162193 COQ3 methylates DHDB IEA Mus musculus 62796 R-RNO-2162193 https://reactome.org/PathwayBrowser/#/R-RNO-2162193 COQ3 methylates DHDB IEA Rattus norvegicus 62796 R-SCE-2162193 https://reactome.org/PathwayBrowser/#/R-SCE-2162193 COQ3 methylates DHDB IEA Saccharomyces cerevisiae 62796 R-SPO-2162193 https://reactome.org/PathwayBrowser/#/R-SPO-2162193 COQ3 methylates DHDB IEA Schizosaccharomyces pombe 62796 R-SSC-2162193 https://reactome.org/PathwayBrowser/#/R-SSC-2162193 COQ3 methylates DHDB IEA Sus scrofa 62796 R-XTR-2162193 https://reactome.org/PathwayBrowser/#/R-XTR-2162193 COQ3 methylates DHDB IEA Xenopus tropicalis 62833 R-BTA-8878654 https://reactome.org/PathwayBrowser/#/R-BTA-8878654 ACP6 hydrolyses MYS-LPA IEA Bos taurus 62833 R-CEL-8878654 https://reactome.org/PathwayBrowser/#/R-CEL-8878654 ACP6 hydrolyses MYS-LPA IEA Caenorhabditis elegans 62833 R-CFA-8878654 https://reactome.org/PathwayBrowser/#/R-CFA-8878654 ACP6 hydrolyses MYS-LPA IEA Canis familiaris 62833 R-DDI-8878654 https://reactome.org/PathwayBrowser/#/R-DDI-8878654 ACP6 hydrolyses MYS-LPA IEA Dictyostelium discoideum 62833 R-DRE-8878654 https://reactome.org/PathwayBrowser/#/R-DRE-8878654 ACP6 hydrolyses MYS-LPA IEA Danio rerio 62833 R-GGA-8878654 https://reactome.org/PathwayBrowser/#/R-GGA-8878654 ACP6 hydrolyses MYS-LPA IEA Gallus gallus 62833 R-HSA-8878654 https://reactome.org/PathwayBrowser/#/R-HSA-8878654 ACP6 hydrolyses MYS-LPA TAS Homo sapiens 62833 R-MMU-8878654 https://reactome.org/PathwayBrowser/#/R-MMU-8878654 ACP6 hydrolyses MYS-LPA IEA Mus musculus 62833 R-RNO-8878654 https://reactome.org/PathwayBrowser/#/R-RNO-8878654 ACP6 hydrolyses MYS-LPA IEA Rattus norvegicus 62833 R-SPO-8878654 https://reactome.org/PathwayBrowser/#/R-SPO-8878654 ACP6 hydrolyses MYS-LPA IEA Schizosaccharomyces pombe 62833 R-SSC-8878654 https://reactome.org/PathwayBrowser/#/R-SSC-8878654 ACP6 hydrolyses MYS-LPA IEA Sus scrofa 62833 R-XTR-8878654 https://reactome.org/PathwayBrowser/#/R-XTR-8878654 ACP6 hydrolyses MYS-LPA IEA Xenopus tropicalis 62845 R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 62845 R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 62845 R-DRE-211951 https://reactome.org/PathwayBrowser/#/R-DRE-211951 CYP1B1 4-hydroxylates EST17b IEA Danio rerio 62845 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 62845 R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 62845 R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 62845 R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 62845 R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 62856 R-BTA-1614567 https://reactome.org/PathwayBrowser/#/R-BTA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Bos taurus 62856 R-CEL-1614567 https://reactome.org/PathwayBrowser/#/R-CEL-1614567 Excess homocysteine yields homolanthionine and H2S IEA Caenorhabditis elegans 62856 R-CFA-1614567 https://reactome.org/PathwayBrowser/#/R-CFA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Canis familiaris 62856 R-DDI-1614567 https://reactome.org/PathwayBrowser/#/R-DDI-1614567 Excess homocysteine yields homolanthionine and H2S IEA Dictyostelium discoideum 62856 R-DME-1614567 https://reactome.org/PathwayBrowser/#/R-DME-1614567 Excess homocysteine yields homolanthionine and H2S IEA Drosophila melanogaster 62856 R-DRE-1614567 https://reactome.org/PathwayBrowser/#/R-DRE-1614567 Excess homocysteine yields homolanthionine and H2S IEA Danio rerio 62856 R-GGA-1614567 https://reactome.org/PathwayBrowser/#/R-GGA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Gallus gallus 62856 R-HSA-1614567 https://reactome.org/PathwayBrowser/#/R-HSA-1614567 Excess homocysteine yields homolanthionine and H2S TAS Homo sapiens 62856 R-MMU-1614567 https://reactome.org/PathwayBrowser/#/R-MMU-1614567 Excess homocysteine yields homolanthionine and H2S IEA Mus musculus 62856 R-RNO-1614567 https://reactome.org/PathwayBrowser/#/R-RNO-1614567 Excess homocysteine yields homolanthionine and H2S IEA Rattus norvegicus 62856 R-SCE-1614567 https://reactome.org/PathwayBrowser/#/R-SCE-1614567 Excess homocysteine yields homolanthionine and H2S IEA Saccharomyces cerevisiae 62856 R-SPO-1614567 https://reactome.org/PathwayBrowser/#/R-SPO-1614567 Excess homocysteine yields homolanthionine and H2S IEA Schizosaccharomyces pombe 62856 R-SSC-1614567 https://reactome.org/PathwayBrowser/#/R-SSC-1614567 Excess homocysteine yields homolanthionine and H2S IEA Sus scrofa 62856 R-XTR-1614567 https://reactome.org/PathwayBrowser/#/R-XTR-1614567 Excess homocysteine yields homolanthionine and H2S IEA Xenopus tropicalis 62877 R-BTA-8953339 https://reactome.org/PathwayBrowser/#/R-BTA-8953339 DNPH1 hydrolyses dGMP IEA Bos taurus 62877 R-CFA-8953339 https://reactome.org/PathwayBrowser/#/R-CFA-8953339 DNPH1 hydrolyses dGMP IEA Canis familiaris 62877 R-DRE-8953339 https://reactome.org/PathwayBrowser/#/R-DRE-8953339 DNPH1 hydrolyses dGMP IEA Danio rerio 62877 R-HSA-8953339 https://reactome.org/PathwayBrowser/#/R-HSA-8953339 DNPH1 hydrolyses dGMP TAS Homo sapiens 62877 R-MMU-8953339 https://reactome.org/PathwayBrowser/#/R-MMU-8953339 DNPH1 hydrolyses dGMP IEA Mus musculus 62877 R-RNO-8953339 https://reactome.org/PathwayBrowser/#/R-RNO-8953339 DNPH1 hydrolyses dGMP IEA Rattus norvegicus 62877 R-SSC-8953339 https://reactome.org/PathwayBrowser/#/R-SSC-8953339 DNPH1 hydrolyses dGMP IEA Sus scrofa 62878 R-HSA-5262606 https://reactome.org/PathwayBrowser/#/R-HSA-5262606 XAV939 binds tankyrase to stabilize axin and inhibit WNT signaling TAS Homo sapiens 62884 R-HSA-6784462 https://reactome.org/PathwayBrowser/#/R-HSA-6784462 TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs IEA Homo sapiens 62884 R-HSA-6787567 https://reactome.org/PathwayBrowser/#/R-HSA-6787567 TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) TAS Homo sapiens 62884 R-SCE-6790167 https://reactome.org/PathwayBrowser/#/R-SCE-6790167 MOD5 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) TAS Saccharomyces cerevisiae 62885 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 62885 R-HSA-6782336 https://reactome.org/PathwayBrowser/#/R-HSA-6782336 ADAT1 deaminates adenosine-37 in tRNA(Ala) IEA Homo sapiens 62885 R-HSA-6783492 https://reactome.org/PathwayBrowser/#/R-HSA-6783492 TRMT6:TRMT61A methylate adenosine yielding 1-methyladenosine at nucleotide 58 of tRNA(Met) TAS Homo sapiens 62885 R-HSA-6784462 https://reactome.org/PathwayBrowser/#/R-HSA-6784462 TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs IEA Homo sapiens 62885 R-HSA-6784494 https://reactome.org/PathwayBrowser/#/R-HSA-6784494 EKC complex threonylcarbamoylates A37 of tRNAs IEA Homo sapiens 62885 R-HSA-6787525 https://reactome.org/PathwayBrowser/#/R-HSA-6787525 TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58 TAS Homo sapiens 62885 R-HSA-6787567 https://reactome.org/PathwayBrowser/#/R-HSA-6787567 TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) TAS Homo sapiens 62885 R-HSA-6787594 https://reactome.org/PathwayBrowser/#/R-HSA-6787594 TRMT10C:HSD17B10 (TRMT10C:SDR5C1) methylates adenosine-9 in tRNA yielding 1-methyladenosine-9 TAS Homo sapiens 62885 R-HSA-6788668 https://reactome.org/PathwayBrowser/#/R-HSA-6788668 TRMT13 2'-O-methylates adenosine-4 in tRNA IEA Homo sapiens 62885 R-SCE-6784469 https://reactome.org/PathwayBrowser/#/R-SCE-6784469 EKC/KEOPS complex threonylcarbamoylates adenosine-37 of tRNAs TAS Saccharomyces cerevisiae 62885 R-SCE-6788665 https://reactome.org/PathwayBrowser/#/R-SCE-6788665 TRM13 2'-O-methylates adenosine-4 in tRNA TAS Saccharomyces cerevisiae 62885 R-SCE-6790128 https://reactome.org/PathwayBrowser/#/R-SCE-6790128 TAD1 deaminates adenosine-37 in tRNA(Ala) yielding inosine-37 TAS Saccharomyces cerevisiae 62885 R-SCE-6790167 https://reactome.org/PathwayBrowser/#/R-SCE-6790167 MOD5 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) TAS Saccharomyces cerevisiae 62918 R-BTA-1855159 https://reactome.org/PathwayBrowser/#/R-BTA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Bos taurus 62918 R-BTA-1855169 https://reactome.org/PathwayBrowser/#/R-BTA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Bos taurus 62918 R-CFA-1855159 https://reactome.org/PathwayBrowser/#/R-CFA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Canis familiaris 62918 R-CFA-1855169 https://reactome.org/PathwayBrowser/#/R-CFA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 62918 R-DDI-1855159 https://reactome.org/PathwayBrowser/#/R-DDI-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 62918 R-DDI-1855169 https://reactome.org/PathwayBrowser/#/R-DDI-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 62918 R-DRE-1855159 https://reactome.org/PathwayBrowser/#/R-DRE-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Danio rerio 62918 R-DRE-1855169 https://reactome.org/PathwayBrowser/#/R-DRE-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Danio rerio 62918 R-GGA-1855159 https://reactome.org/PathwayBrowser/#/R-GGA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Gallus gallus 62918 R-GGA-1855169 https://reactome.org/PathwayBrowser/#/R-GGA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 62918 R-HSA-1855159 https://reactome.org/PathwayBrowser/#/R-HSA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol TAS Homo sapiens 62918 R-HSA-1855169 https://reactome.org/PathwayBrowser/#/R-HSA-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 62918 R-MMU-1855159 https://reactome.org/PathwayBrowser/#/R-MMU-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Mus musculus 62918 R-MMU-1855169 https://reactome.org/PathwayBrowser/#/R-MMU-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Mus musculus 62918 R-RNO-1855159 https://reactome.org/PathwayBrowser/#/R-RNO-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 62918 R-RNO-1855169 https://reactome.org/PathwayBrowser/#/R-RNO-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 62918 R-SSC-1855159 https://reactome.org/PathwayBrowser/#/R-SSC-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Sus scrofa 62918 R-SSC-1855169 https://reactome.org/PathwayBrowser/#/R-SSC-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 62918 R-XTR-1855159 https://reactome.org/PathwayBrowser/#/R-XTR-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 62918 R-XTR-1855169 https://reactome.org/PathwayBrowser/#/R-XTR-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 62926 R-BTA-1855166 https://reactome.org/PathwayBrowser/#/R-BTA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Bos taurus 62926 R-BTA-1855193 https://reactome.org/PathwayBrowser/#/R-BTA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Bos taurus 62926 R-CEL-1855166 https://reactome.org/PathwayBrowser/#/R-CEL-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Caenorhabditis elegans 62926 R-CEL-1855193 https://reactome.org/PathwayBrowser/#/R-CEL-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 62926 R-CFA-1855166 https://reactome.org/PathwayBrowser/#/R-CFA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Canis familiaris 62926 R-CFA-1855193 https://reactome.org/PathwayBrowser/#/R-CFA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Canis familiaris 62926 R-DDI-1855166 https://reactome.org/PathwayBrowser/#/R-DDI-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Dictyostelium discoideum 62926 R-DDI-1855193 https://reactome.org/PathwayBrowser/#/R-DDI-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 62926 R-DME-1855166 https://reactome.org/PathwayBrowser/#/R-DME-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Drosophila melanogaster 62926 R-DME-1855193 https://reactome.org/PathwayBrowser/#/R-DME-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 62926 R-DRE-1855166 https://reactome.org/PathwayBrowser/#/R-DRE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Danio rerio 62926 R-DRE-1855193 https://reactome.org/PathwayBrowser/#/R-DRE-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Danio rerio 62926 R-GGA-1855166 https://reactome.org/PathwayBrowser/#/R-GGA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Gallus gallus 62926 R-GGA-1855193 https://reactome.org/PathwayBrowser/#/R-GGA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Gallus gallus 62926 R-HSA-1855166 https://reactome.org/PathwayBrowser/#/R-HSA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol TAS Homo sapiens 62926 R-HSA-1855193 https://reactome.org/PathwayBrowser/#/R-HSA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol TAS Homo sapiens 62926 R-MMU-1855166 https://reactome.org/PathwayBrowser/#/R-MMU-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Mus musculus 62926 R-MMU-1855193 https://reactome.org/PathwayBrowser/#/R-MMU-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Mus musculus 62926 R-PFA-1855193 https://reactome.org/PathwayBrowser/#/R-PFA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 62926 R-RNO-1855166 https://reactome.org/PathwayBrowser/#/R-RNO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Rattus norvegicus 62926 R-RNO-1855193 https://reactome.org/PathwayBrowser/#/R-RNO-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Rattus norvegicus 62926 R-SCE-1855166 https://reactome.org/PathwayBrowser/#/R-SCE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Saccharomyces cerevisiae 62926 R-SCE-1855193 https://reactome.org/PathwayBrowser/#/R-SCE-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 62926 R-SPO-1855166 https://reactome.org/PathwayBrowser/#/R-SPO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Schizosaccharomyces pombe 62926 R-SPO-1855193 https://reactome.org/PathwayBrowser/#/R-SPO-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 62926 R-SSC-1855166 https://reactome.org/PathwayBrowser/#/R-SSC-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Sus scrofa 62926 R-SSC-1855193 https://reactome.org/PathwayBrowser/#/R-SSC-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Sus scrofa 62926 R-XTR-1855166 https://reactome.org/PathwayBrowser/#/R-XTR-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Xenopus tropicalis 62926 R-XTR-1855193 https://reactome.org/PathwayBrowser/#/R-XTR-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 62927 R-BTA-1855166 https://reactome.org/PathwayBrowser/#/R-BTA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Bos taurus 62927 R-CEL-1855166 https://reactome.org/PathwayBrowser/#/R-CEL-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Caenorhabditis elegans 62927 R-CFA-1855166 https://reactome.org/PathwayBrowser/#/R-CFA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Canis familiaris 62927 R-DDI-1855166 https://reactome.org/PathwayBrowser/#/R-DDI-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Dictyostelium discoideum 62927 R-DME-1855166 https://reactome.org/PathwayBrowser/#/R-DME-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Drosophila melanogaster 62927 R-DRE-1855166 https://reactome.org/PathwayBrowser/#/R-DRE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Danio rerio 62927 R-GGA-1855166 https://reactome.org/PathwayBrowser/#/R-GGA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Gallus gallus 62927 R-HSA-1855166 https://reactome.org/PathwayBrowser/#/R-HSA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol TAS Homo sapiens 62927 R-MMU-1855166 https://reactome.org/PathwayBrowser/#/R-MMU-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Mus musculus 62927 R-RNO-1855166 https://reactome.org/PathwayBrowser/#/R-RNO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Rattus norvegicus 62927 R-SCE-1855166 https://reactome.org/PathwayBrowser/#/R-SCE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Saccharomyces cerevisiae 62927 R-SPO-1855166 https://reactome.org/PathwayBrowser/#/R-SPO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Schizosaccharomyces pombe 62927 R-SSC-1855166 https://reactome.org/PathwayBrowser/#/R-SSC-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Sus scrofa 62927 R-XTR-1855166 https://reactome.org/PathwayBrowser/#/R-XTR-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Xenopus tropicalis 62928 R-BTA-1855166 https://reactome.org/PathwayBrowser/#/R-BTA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Bos taurus 62928 R-BTA-1855181 https://reactome.org/PathwayBrowser/#/R-BTA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Bos taurus 62928 R-BTA-1855223 https://reactome.org/PathwayBrowser/#/R-BTA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Bos taurus 62928 R-BTA-1855230 https://reactome.org/PathwayBrowser/#/R-BTA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Bos taurus 62928 R-CEL-1855166 https://reactome.org/PathwayBrowser/#/R-CEL-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Caenorhabditis elegans 62928 R-CEL-1855181 https://reactome.org/PathwayBrowser/#/R-CEL-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 62928 R-CEL-1855223 https://reactome.org/PathwayBrowser/#/R-CEL-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 62928 R-CEL-1855230 https://reactome.org/PathwayBrowser/#/R-CEL-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 62928 R-CFA-1855166 https://reactome.org/PathwayBrowser/#/R-CFA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Canis familiaris 62928 R-CFA-1855181 https://reactome.org/PathwayBrowser/#/R-CFA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Canis familiaris 62928 R-CFA-1855223 https://reactome.org/PathwayBrowser/#/R-CFA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Canis familiaris 62928 R-CFA-1855230 https://reactome.org/PathwayBrowser/#/R-CFA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Canis familiaris 62928 R-DDI-1855166 https://reactome.org/PathwayBrowser/#/R-DDI-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Dictyostelium discoideum 62928 R-DDI-1855181 https://reactome.org/PathwayBrowser/#/R-DDI-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 62928 R-DDI-1855223 https://reactome.org/PathwayBrowser/#/R-DDI-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 62928 R-DDI-1855230 https://reactome.org/PathwayBrowser/#/R-DDI-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 62928 R-DME-1855166 https://reactome.org/PathwayBrowser/#/R-DME-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Drosophila melanogaster 62928 R-DME-1855181 https://reactome.org/PathwayBrowser/#/R-DME-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 62928 R-DME-1855223 https://reactome.org/PathwayBrowser/#/R-DME-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 62928 R-DME-1855230 https://reactome.org/PathwayBrowser/#/R-DME-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 62928 R-DRE-1855166 https://reactome.org/PathwayBrowser/#/R-DRE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Danio rerio 62928 R-DRE-1855181 https://reactome.org/PathwayBrowser/#/R-DRE-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Danio rerio 62928 R-DRE-1855223 https://reactome.org/PathwayBrowser/#/R-DRE-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Danio rerio 62928 R-DRE-1855230 https://reactome.org/PathwayBrowser/#/R-DRE-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Danio rerio 62928 R-GGA-1855166 https://reactome.org/PathwayBrowser/#/R-GGA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Gallus gallus 62928 R-GGA-1855181 https://reactome.org/PathwayBrowser/#/R-GGA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Gallus gallus 62928 R-GGA-1855223 https://reactome.org/PathwayBrowser/#/R-GGA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Gallus gallus 62928 R-GGA-1855230 https://reactome.org/PathwayBrowser/#/R-GGA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Gallus gallus 62928 R-HSA-1855166 https://reactome.org/PathwayBrowser/#/R-HSA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol TAS Homo sapiens 62928 R-HSA-1855173 https://reactome.org/PathwayBrowser/#/R-HSA-1855173 5-PP-IP4 transports from the nucleus to the cytosol TAS Homo sapiens 62928 R-HSA-1855181 https://reactome.org/PathwayBrowser/#/R-HSA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus TAS Homo sapiens 62928 R-HSA-1855223 https://reactome.org/PathwayBrowser/#/R-HSA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol TAS Homo sapiens 62928 R-HSA-1855230 https://reactome.org/PathwayBrowser/#/R-HSA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus TAS Homo sapiens 62928 R-MMU-1855166 https://reactome.org/PathwayBrowser/#/R-MMU-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Mus musculus 62928 R-MMU-1855181 https://reactome.org/PathwayBrowser/#/R-MMU-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Mus musculus 62928 R-MMU-1855223 https://reactome.org/PathwayBrowser/#/R-MMU-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Mus musculus 62928 R-MMU-1855230 https://reactome.org/PathwayBrowser/#/R-MMU-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Mus musculus 62928 R-PFA-1855181 https://reactome.org/PathwayBrowser/#/R-PFA-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 62928 R-PFA-1855223 https://reactome.org/PathwayBrowser/#/R-PFA-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 62928 R-PFA-1855230 https://reactome.org/PathwayBrowser/#/R-PFA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 62928 R-RNO-1855166 https://reactome.org/PathwayBrowser/#/R-RNO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Rattus norvegicus 62928 R-RNO-1855181 https://reactome.org/PathwayBrowser/#/R-RNO-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Rattus norvegicus 62928 R-RNO-1855223 https://reactome.org/PathwayBrowser/#/R-RNO-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Rattus norvegicus 62928 R-RNO-1855230 https://reactome.org/PathwayBrowser/#/R-RNO-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Rattus norvegicus 62928 R-SCE-1855166 https://reactome.org/PathwayBrowser/#/R-SCE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Saccharomyces cerevisiae 62928 R-SCE-1855181 https://reactome.org/PathwayBrowser/#/R-SCE-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 62928 R-SCE-1855223 https://reactome.org/PathwayBrowser/#/R-SCE-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 62928 R-SCE-1855230 https://reactome.org/PathwayBrowser/#/R-SCE-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 62928 R-SPO-1855166 https://reactome.org/PathwayBrowser/#/R-SPO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Schizosaccharomyces pombe 62928 R-SPO-1855181 https://reactome.org/PathwayBrowser/#/R-SPO-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 62928 R-SPO-1855223 https://reactome.org/PathwayBrowser/#/R-SPO-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 62928 R-SPO-1855230 https://reactome.org/PathwayBrowser/#/R-SPO-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 62928 R-SSC-1855166 https://reactome.org/PathwayBrowser/#/R-SSC-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Sus scrofa 62928 R-SSC-1855181 https://reactome.org/PathwayBrowser/#/R-SSC-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Sus scrofa 62928 R-SSC-1855223 https://reactome.org/PathwayBrowser/#/R-SSC-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Sus scrofa 62928 R-SSC-1855230 https://reactome.org/PathwayBrowser/#/R-SSC-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Sus scrofa 62928 R-XTR-1855166 https://reactome.org/PathwayBrowser/#/R-XTR-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Xenopus tropicalis 62928 R-XTR-1855181 https://reactome.org/PathwayBrowser/#/R-XTR-1855181 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 62928 R-XTR-1855223 https://reactome.org/PathwayBrowser/#/R-XTR-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 62928 R-XTR-1855230 https://reactome.org/PathwayBrowser/#/R-XTR-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 62931 R-BTA-1855193 https://reactome.org/PathwayBrowser/#/R-BTA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Bos taurus 62931 R-BTA-1855230 https://reactome.org/PathwayBrowser/#/R-BTA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Bos taurus 62931 R-CEL-1855193 https://reactome.org/PathwayBrowser/#/R-CEL-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 62931 R-CEL-1855230 https://reactome.org/PathwayBrowser/#/R-CEL-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 62931 R-CFA-1855193 https://reactome.org/PathwayBrowser/#/R-CFA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Canis familiaris 62931 R-CFA-1855230 https://reactome.org/PathwayBrowser/#/R-CFA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Canis familiaris 62931 R-DDI-1855193 https://reactome.org/PathwayBrowser/#/R-DDI-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 62931 R-DDI-1855230 https://reactome.org/PathwayBrowser/#/R-DDI-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 62931 R-DME-1855193 https://reactome.org/PathwayBrowser/#/R-DME-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 62931 R-DME-1855230 https://reactome.org/PathwayBrowser/#/R-DME-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 62931 R-DRE-1855193 https://reactome.org/PathwayBrowser/#/R-DRE-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Danio rerio 62931 R-DRE-1855230 https://reactome.org/PathwayBrowser/#/R-DRE-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Danio rerio 62931 R-GGA-1855193 https://reactome.org/PathwayBrowser/#/R-GGA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Gallus gallus 62931 R-GGA-1855230 https://reactome.org/PathwayBrowser/#/R-GGA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Gallus gallus 62931 R-HSA-1855193 https://reactome.org/PathwayBrowser/#/R-HSA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol TAS Homo sapiens 62931 R-HSA-1855230 https://reactome.org/PathwayBrowser/#/R-HSA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus TAS Homo sapiens 62931 R-MMU-1855193 https://reactome.org/PathwayBrowser/#/R-MMU-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Mus musculus 62931 R-MMU-1855230 https://reactome.org/PathwayBrowser/#/R-MMU-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Mus musculus 62931 R-PFA-1855193 https://reactome.org/PathwayBrowser/#/R-PFA-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 62931 R-PFA-1855230 https://reactome.org/PathwayBrowser/#/R-PFA-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 62931 R-RNO-1855193 https://reactome.org/PathwayBrowser/#/R-RNO-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Rattus norvegicus 62931 R-RNO-1855230 https://reactome.org/PathwayBrowser/#/R-RNO-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Rattus norvegicus 62931 R-SCE-1855193 https://reactome.org/PathwayBrowser/#/R-SCE-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 62931 R-SCE-1855230 https://reactome.org/PathwayBrowser/#/R-SCE-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 62931 R-SPO-1855193 https://reactome.org/PathwayBrowser/#/R-SPO-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 62931 R-SPO-1855230 https://reactome.org/PathwayBrowser/#/R-SPO-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 62931 R-SSC-1855193 https://reactome.org/PathwayBrowser/#/R-SSC-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Sus scrofa 62931 R-SSC-1855230 https://reactome.org/PathwayBrowser/#/R-SSC-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Sus scrofa 62931 R-XTR-1855193 https://reactome.org/PathwayBrowser/#/R-XTR-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 62931 R-XTR-1855230 https://reactome.org/PathwayBrowser/#/R-XTR-1855230 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 62932 R-BTA-5694563 https://reactome.org/PathwayBrowser/#/R-BTA-5694563 ABHD10 hydrolyses MPAG IEA Bos taurus 62932 R-CFA-5694563 https://reactome.org/PathwayBrowser/#/R-CFA-5694563 ABHD10 hydrolyses MPAG IEA Canis familiaris 62932 R-GGA-5694563 https://reactome.org/PathwayBrowser/#/R-GGA-5694563 ABHD10 hydrolyses MPAG IEA Gallus gallus 62932 R-HSA-5694563 https://reactome.org/PathwayBrowser/#/R-HSA-5694563 ABHD10 hydrolyses MPAG TAS Homo sapiens 62932 R-MMU-5694563 https://reactome.org/PathwayBrowser/#/R-MMU-5694563 ABHD10 hydrolyses MPAG IEA Mus musculus 62932 R-RNO-5694563 https://reactome.org/PathwayBrowser/#/R-RNO-5694563 ABHD10 hydrolyses MPAG IEA Rattus norvegicus 62932 R-SSC-5694563 https://reactome.org/PathwayBrowser/#/R-SSC-5694563 ABHD10 hydrolyses MPAG IEA Sus scrofa 62932 R-XTR-5694563 https://reactome.org/PathwayBrowser/#/R-XTR-5694563 ABHD10 hydrolyses MPAG IEA Xenopus tropicalis 62985 R-BTA-1855158 https://reactome.org/PathwayBrowser/#/R-BTA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Bos taurus 62985 R-BTA-1855224 https://reactome.org/PathwayBrowser/#/R-BTA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Bos taurus 62985 R-CEL-1855158 https://reactome.org/PathwayBrowser/#/R-CEL-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 62985 R-CEL-1855224 https://reactome.org/PathwayBrowser/#/R-CEL-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 62985 R-CFA-1855158 https://reactome.org/PathwayBrowser/#/R-CFA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Canis familiaris 62985 R-CFA-1855224 https://reactome.org/PathwayBrowser/#/R-CFA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Canis familiaris 62985 R-DDI-1855158 https://reactome.org/PathwayBrowser/#/R-DDI-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 62985 R-DDI-1855224 https://reactome.org/PathwayBrowser/#/R-DDI-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 62985 R-DME-1855158 https://reactome.org/PathwayBrowser/#/R-DME-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 62985 R-DME-1855224 https://reactome.org/PathwayBrowser/#/R-DME-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 62985 R-DRE-1855158 https://reactome.org/PathwayBrowser/#/R-DRE-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Danio rerio 62985 R-DRE-1855224 https://reactome.org/PathwayBrowser/#/R-DRE-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Danio rerio 62985 R-GGA-1855158 https://reactome.org/PathwayBrowser/#/R-GGA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Gallus gallus 62985 R-GGA-1855224 https://reactome.org/PathwayBrowser/#/R-GGA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Gallus gallus 62985 R-HSA-1855158 https://reactome.org/PathwayBrowser/#/R-HSA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol TAS Homo sapiens 62985 R-HSA-1855224 https://reactome.org/PathwayBrowser/#/R-HSA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus TAS Homo sapiens 62985 R-MMU-1855158 https://reactome.org/PathwayBrowser/#/R-MMU-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Mus musculus 62985 R-MMU-1855224 https://reactome.org/PathwayBrowser/#/R-MMU-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Mus musculus 62985 R-PFA-1855158 https://reactome.org/PathwayBrowser/#/R-PFA-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 62985 R-PFA-1855224 https://reactome.org/PathwayBrowser/#/R-PFA-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 62985 R-RNO-1855158 https://reactome.org/PathwayBrowser/#/R-RNO-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Rattus norvegicus 62985 R-RNO-1855224 https://reactome.org/PathwayBrowser/#/R-RNO-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Rattus norvegicus 62985 R-SCE-1855158 https://reactome.org/PathwayBrowser/#/R-SCE-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 62985 R-SCE-1855224 https://reactome.org/PathwayBrowser/#/R-SCE-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 62985 R-SPO-1855158 https://reactome.org/PathwayBrowser/#/R-SPO-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 62985 R-SPO-1855224 https://reactome.org/PathwayBrowser/#/R-SPO-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 62985 R-SSC-1855158 https://reactome.org/PathwayBrowser/#/R-SSC-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Sus scrofa 62985 R-SSC-1855224 https://reactome.org/PathwayBrowser/#/R-SSC-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Sus scrofa 62985 R-XTR-1855158 https://reactome.org/PathwayBrowser/#/R-XTR-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 62985 R-XTR-1855224 https://reactome.org/PathwayBrowser/#/R-XTR-1855224 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 62989 R-BTA-159425 https://reactome.org/PathwayBrowser/#/R-BTA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 62989 R-BTA-193533 https://reactome.org/PathwayBrowser/#/R-BTA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Bos taurus 62989 R-CEL-159425 https://reactome.org/PathwayBrowser/#/R-CEL-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 62989 R-CEL-159431 https://reactome.org/PathwayBrowser/#/R-CEL-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Caenorhabditis elegans 62989 R-CEL-193491 https://reactome.org/PathwayBrowser/#/R-CEL-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Caenorhabditis elegans 62989 R-CFA-159425 https://reactome.org/PathwayBrowser/#/R-CFA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 62989 R-CFA-159431 https://reactome.org/PathwayBrowser/#/R-CFA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Canis familiaris 62989 R-CFA-193491 https://reactome.org/PathwayBrowser/#/R-CFA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Canis familiaris 62989 R-CFA-193533 https://reactome.org/PathwayBrowser/#/R-CFA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Canis familiaris 62989 R-DME-159425 https://reactome.org/PathwayBrowser/#/R-DME-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 62989 R-DME-193533 https://reactome.org/PathwayBrowser/#/R-DME-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Drosophila melanogaster 62989 R-DRE-159425 https://reactome.org/PathwayBrowser/#/R-DRE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 62989 R-DRE-193533 https://reactome.org/PathwayBrowser/#/R-DRE-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Danio rerio 62989 R-GGA-159425 https://reactome.org/PathwayBrowser/#/R-GGA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 62989 R-GGA-159431 https://reactome.org/PathwayBrowser/#/R-GGA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Gallus gallus 62989 R-GGA-193491 https://reactome.org/PathwayBrowser/#/R-GGA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Gallus gallus 62989 R-GGA-193533 https://reactome.org/PathwayBrowser/#/R-GGA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Gallus gallus 62989 R-HSA-159425 https://reactome.org/PathwayBrowser/#/R-HSA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 62989 R-HSA-159431 https://reactome.org/PathwayBrowser/#/R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine TAS Homo sapiens 62989 R-HSA-193491 https://reactome.org/PathwayBrowser/#/R-HSA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate TAS Homo sapiens 62989 R-HSA-193533 https://reactome.org/PathwayBrowser/#/R-HSA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA TAS Homo sapiens 62989 R-MMU-159425 https://reactome.org/PathwayBrowser/#/R-MMU-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 62989 R-MMU-159431 https://reactome.org/PathwayBrowser/#/R-MMU-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Mus musculus 62989 R-MMU-193491 https://reactome.org/PathwayBrowser/#/R-MMU-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Mus musculus 62989 R-MMU-193533 https://reactome.org/PathwayBrowser/#/R-MMU-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Mus musculus 62989 R-RNO-159425 https://reactome.org/PathwayBrowser/#/R-RNO-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 62989 R-RNO-159431 https://reactome.org/PathwayBrowser/#/R-RNO-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Rattus norvegicus 62989 R-RNO-193491 https://reactome.org/PathwayBrowser/#/R-RNO-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Rattus norvegicus 62989 R-RNO-193533 https://reactome.org/PathwayBrowser/#/R-RNO-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA IEA Rattus norvegicus 62989 R-SCE-159425 https://reactome.org/PathwayBrowser/#/R-SCE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 62989 R-SSC-159425 https://reactome.org/PathwayBrowser/#/R-SSC-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 62989 R-SSC-159431 https://reactome.org/PathwayBrowser/#/R-SSC-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Sus scrofa 62989 R-SSC-193491 https://reactome.org/PathwayBrowser/#/R-SSC-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Sus scrofa 62989 R-XTR-159425 https://reactome.org/PathwayBrowser/#/R-XTR-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 62989 R-XTR-159431 https://reactome.org/PathwayBrowser/#/R-XTR-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Xenopus tropicalis 62989 R-XTR-193491 https://reactome.org/PathwayBrowser/#/R-XTR-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Xenopus tropicalis 63212 R-BTA-2395818 https://reactome.org/PathwayBrowser/#/R-BTA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Bos taurus 63212 R-CFA-2395818 https://reactome.org/PathwayBrowser/#/R-CFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Canis familiaris 63212 R-DRE-2395818 https://reactome.org/PathwayBrowser/#/R-DRE-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Danio rerio 63212 R-GGA-2395818 https://reactome.org/PathwayBrowser/#/R-GGA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Gallus gallus 63212 R-HSA-2395818 https://reactome.org/PathwayBrowser/#/R-HSA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP TAS Homo sapiens 63212 R-MMU-2395818 https://reactome.org/PathwayBrowser/#/R-MMU-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Mus musculus 63212 R-PFA-2395818 https://reactome.org/PathwayBrowser/#/R-PFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Plasmodium falciparum 63212 R-RNO-2395818 https://reactome.org/PathwayBrowser/#/R-RNO-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Rattus norvegicus 63212 R-SSC-2395818 https://reactome.org/PathwayBrowser/#/R-SSC-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Sus scrofa 63212 R-XTR-2395818 https://reactome.org/PathwayBrowser/#/R-XTR-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Xenopus tropicalis 63224 R-BTA-2395849 https://reactome.org/PathwayBrowser/#/R-BTA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 63224 R-BTA-2395869 https://reactome.org/PathwayBrowser/#/R-BTA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 63224 R-BTA-2395876 https://reactome.org/PathwayBrowser/#/R-BTA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 63224 R-BTA-2395879 https://reactome.org/PathwayBrowser/#/R-BTA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 63224 R-CEL-2395879 https://reactome.org/PathwayBrowser/#/R-CEL-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Caenorhabditis elegans 63224 R-CFA-2395849 https://reactome.org/PathwayBrowser/#/R-CFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 63224 R-CFA-2395869 https://reactome.org/PathwayBrowser/#/R-CFA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 63224 R-CFA-2395876 https://reactome.org/PathwayBrowser/#/R-CFA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 63224 R-CFA-2395879 https://reactome.org/PathwayBrowser/#/R-CFA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 63224 R-DME-2395879 https://reactome.org/PathwayBrowser/#/R-DME-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Drosophila melanogaster 63224 R-DRE-2395849 https://reactome.org/PathwayBrowser/#/R-DRE-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Danio rerio 63224 R-DRE-2395879 https://reactome.org/PathwayBrowser/#/R-DRE-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Danio rerio 63224 R-GGA-2395849 https://reactome.org/PathwayBrowser/#/R-GGA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 63224 R-GGA-2395869 https://reactome.org/PathwayBrowser/#/R-GGA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 63224 R-GGA-2395876 https://reactome.org/PathwayBrowser/#/R-GGA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Gallus gallus 63224 R-HSA-2395849 https://reactome.org/PathwayBrowser/#/R-HSA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 63224 R-HSA-2395869 https://reactome.org/PathwayBrowser/#/R-HSA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 63224 R-HSA-2395876 https://reactome.org/PathwayBrowser/#/R-HSA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 63224 R-HSA-2395879 https://reactome.org/PathwayBrowser/#/R-HSA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 63224 R-MMU-2395849 https://reactome.org/PathwayBrowser/#/R-MMU-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 63224 R-MMU-2395869 https://reactome.org/PathwayBrowser/#/R-MMU-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 63224 R-MMU-2395876 https://reactome.org/PathwayBrowser/#/R-MMU-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 63224 R-MMU-2395879 https://reactome.org/PathwayBrowser/#/R-MMU-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 63224 R-PFA-2395849 https://reactome.org/PathwayBrowser/#/R-PFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Plasmodium falciparum 63224 R-RNO-2395849 https://reactome.org/PathwayBrowser/#/R-RNO-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 63224 R-RNO-2395869 https://reactome.org/PathwayBrowser/#/R-RNO-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 63224 R-RNO-2395876 https://reactome.org/PathwayBrowser/#/R-RNO-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 63224 R-RNO-2395879 https://reactome.org/PathwayBrowser/#/R-RNO-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 63224 R-SSC-2395849 https://reactome.org/PathwayBrowser/#/R-SSC-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 63224 R-SSC-2395869 https://reactome.org/PathwayBrowser/#/R-SSC-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 63224 R-SSC-2395876 https://reactome.org/PathwayBrowser/#/R-SSC-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 63224 R-SSC-2395879 https://reactome.org/PathwayBrowser/#/R-SSC-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 63224 R-XTR-2395849 https://reactome.org/PathwayBrowser/#/R-XTR-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 63224 R-XTR-2395869 https://reactome.org/PathwayBrowser/#/R-XTR-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 63224 R-XTR-2395876 https://reactome.org/PathwayBrowser/#/R-XTR-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 63224 R-XTR-2395879 https://reactome.org/PathwayBrowser/#/R-XTR-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 6339 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 6339 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 6339 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 6339 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 6339 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 6339 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 6339 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 6339 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 6339 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 6339 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 6339 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 6339 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 6339 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 6339 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 6339 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 6339 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 6339 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 6339 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 6343 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 6343 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 6343 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 6343 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 6343 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 6343 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 6343 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 6343 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 6343 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 6343 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 6343 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 6343 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 6343 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 6343 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 6343 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 6343 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 6343 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 6343 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 6343 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 6343 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 6343 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 6343 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 6343 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 6343 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 6343 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 6343 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 6343 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 6343 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 6343 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 6343 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 6343 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 6343 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 6343 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 6343 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 6343 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 6343 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 6343 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 63448 R-HSA-1839039 https://reactome.org/PathwayBrowser/#/R-HSA-1839039 Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation TAS Homo sapiens 63448 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 63448 R-HSA-2029992 https://reactome.org/PathwayBrowser/#/R-HSA-2029992 Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants TAS Homo sapiens 63448 R-HSA-2046363 https://reactome.org/PathwayBrowser/#/R-HSA-2046363 FGFR4 kinase mutants are inhibited by PD170734 TAS Homo sapiens 63448 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 63448 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 63449 R-HSA-1839039 https://reactome.org/PathwayBrowser/#/R-HSA-1839039 Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation TAS Homo sapiens 63449 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 63449 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 63449 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 63450 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 63450 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 63450 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 63450 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 63450 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 63450 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 63450 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 63450 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 63450 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 63450 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 63450 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 63450 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 63450 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 63450 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 63450 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 63450 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 63450 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 63450 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 63450 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 63450 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 63450 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 63450 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 63450 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 63450 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 63450 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 63450 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 63450 R-HSA-9669863 https://reactome.org/PathwayBrowser/#/R-HSA-9669863 Masitinib-resistant KIT mutants do not bind masitinib TAS Homo sapiens 63450 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 63450 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 63450 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 63450 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 63450 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 63450 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 63450 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 63450 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 63450 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 63450 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 63450 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 63450 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 63450 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 63450 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 63450 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 63450 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 63450 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 63450 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 63450 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 63451 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 63451 R-HSA-2029992 https://reactome.org/PathwayBrowser/#/R-HSA-2029992 Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants TAS Homo sapiens 63451 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 63451 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 63452 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 63452 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 63452 R-BTA-9669893 https://reactome.org/PathwayBrowser/#/R-BTA-9669893 KIT binds type I TKIs IEA Bos taurus 63452 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 63452 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 63452 R-CFA-9669893 https://reactome.org/PathwayBrowser/#/R-CFA-9669893 KIT binds type I TKIs IEA Canis familiaris 63452 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 63452 R-DRE-9669893 https://reactome.org/PathwayBrowser/#/R-DRE-9669893 KIT binds type I TKIs IEA Danio rerio 63452 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 63452 R-GGA-9669893 https://reactome.org/PathwayBrowser/#/R-GGA-9669893 KIT binds type I TKIs IEA Gallus gallus 63452 R-HSA-1839039 https://reactome.org/PathwayBrowser/#/R-HSA-1839039 Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation TAS Homo sapiens 63452 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 63452 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 63452 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 63452 R-HSA-9669893 https://reactome.org/PathwayBrowser/#/R-HSA-9669893 KIT binds type I TKIs TAS Homo sapiens 63452 R-HSA-9669898 https://reactome.org/PathwayBrowser/#/R-HSA-9669898 KIT mutants bind type I TKIs TAS Homo sapiens 63452 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 63452 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 63452 R-HSA-9702601 https://reactome.org/PathwayBrowser/#/R-HSA-9702601 midostaurin-resistant FLT3 mutants don't bind midostaurin TAS Homo sapiens 63452 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 63452 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 63452 R-MMU-9669893 https://reactome.org/PathwayBrowser/#/R-MMU-9669893 KIT binds type I TKIs IEA Mus musculus 63452 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 63452 R-RNO-9669893 https://reactome.org/PathwayBrowser/#/R-RNO-9669893 KIT binds type I TKIs IEA Rattus norvegicus 63452 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 63452 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 63452 R-SSC-9669893 https://reactome.org/PathwayBrowser/#/R-SSC-9669893 KIT binds type I TKIs IEA Sus scrofa 63452 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 63452 R-XTR-9669893 https://reactome.org/PathwayBrowser/#/R-XTR-9669893 KIT binds type I TKIs IEA Xenopus tropicalis 63453 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 63453 R-HSA-2029992 https://reactome.org/PathwayBrowser/#/R-HSA-2029992 Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants TAS Homo sapiens 63453 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 63453 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 63503 R-BTA-1678854 https://reactome.org/PathwayBrowser/#/R-BTA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Bos taurus 63503 R-BTA-2090079 https://reactome.org/PathwayBrowser/#/R-BTA-2090079 GLB1 hydrolyses linker chain(2) IEA Bos taurus 63503 R-CEL-1678854 https://reactome.org/PathwayBrowser/#/R-CEL-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Caenorhabditis elegans 63503 R-CEL-2090079 https://reactome.org/PathwayBrowser/#/R-CEL-2090079 GLB1 hydrolyses linker chain(2) IEA Caenorhabditis elegans 63503 R-CFA-1678854 https://reactome.org/PathwayBrowser/#/R-CFA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Canis familiaris 63503 R-CFA-2090079 https://reactome.org/PathwayBrowser/#/R-CFA-2090079 GLB1 hydrolyses linker chain(2) IEA Canis familiaris 63503 R-DDI-2090079 https://reactome.org/PathwayBrowser/#/R-DDI-2090079 GLB1 hydrolyses linker chain(2) IEA Dictyostelium discoideum 63503 R-DME-1678854 https://reactome.org/PathwayBrowser/#/R-DME-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Drosophila melanogaster 63503 R-DME-2090079 https://reactome.org/PathwayBrowser/#/R-DME-2090079 GLB1 hydrolyses linker chain(2) IEA Drosophila melanogaster 63503 R-GGA-1678854 https://reactome.org/PathwayBrowser/#/R-GGA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Gallus gallus 63503 R-GGA-2090079 https://reactome.org/PathwayBrowser/#/R-GGA-2090079 GLB1 hydrolyses linker chain(2) IEA Gallus gallus 63503 R-HSA-1678854 https://reactome.org/PathwayBrowser/#/R-HSA-1678854 GUSB tetramer hydrolyses CS/HS precursor TAS Homo sapiens 63503 R-HSA-2090079 https://reactome.org/PathwayBrowser/#/R-HSA-2090079 GLB1 hydrolyses linker chain(2) TAS Homo sapiens 63503 R-HSA-9036061 https://reactome.org/PathwayBrowser/#/R-HSA-9036061 Defective GLB1 does not hydrolyse linker chain(2) TAS Homo sapiens 63503 R-MMU-1678854 https://reactome.org/PathwayBrowser/#/R-MMU-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Mus musculus 63503 R-MMU-2090079 https://reactome.org/PathwayBrowser/#/R-MMU-2090079 GLB1 hydrolyses linker chain(2) IEA Mus musculus 63503 R-RNO-1678854 https://reactome.org/PathwayBrowser/#/R-RNO-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Rattus norvegicus 63503 R-RNO-2090079 https://reactome.org/PathwayBrowser/#/R-RNO-2090079 GLB1 hydrolyses linker chain(2) IEA Rattus norvegicus 63503 R-SSC-1678854 https://reactome.org/PathwayBrowser/#/R-SSC-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Sus scrofa 63503 R-SSC-2090079 https://reactome.org/PathwayBrowser/#/R-SSC-2090079 GLB1 hydrolyses linker chain(2) IEA Sus scrofa 63503 R-XTR-1678854 https://reactome.org/PathwayBrowser/#/R-XTR-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Xenopus tropicalis 63503 R-XTR-2090079 https://reactome.org/PathwayBrowser/#/R-XTR-2090079 GLB1 hydrolyses linker chain(2) IEA Xenopus tropicalis 63505 R-BTA-1678854 https://reactome.org/PathwayBrowser/#/R-BTA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Bos taurus 63505 R-BTA-1793209 https://reactome.org/PathwayBrowser/#/R-BTA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Bos taurus 63505 R-BTA-2090038 https://reactome.org/PathwayBrowser/#/R-BTA-2090038 NAGLU hydrolyses heparan chain(2) IEA Bos taurus 63505 R-CEL-1678854 https://reactome.org/PathwayBrowser/#/R-CEL-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Caenorhabditis elegans 63505 R-CEL-1793209 https://reactome.org/PathwayBrowser/#/R-CEL-1793209 HYAL1 hydrolyses Chondroitin chains IEA Caenorhabditis elegans 63505 R-CEL-2090038 https://reactome.org/PathwayBrowser/#/R-CEL-2090038 NAGLU hydrolyses heparan chain(2) IEA Caenorhabditis elegans 63505 R-CFA-1678854 https://reactome.org/PathwayBrowser/#/R-CFA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Canis familiaris 63505 R-CFA-1793209 https://reactome.org/PathwayBrowser/#/R-CFA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Canis familiaris 63505 R-CFA-2090038 https://reactome.org/PathwayBrowser/#/R-CFA-2090038 NAGLU hydrolyses heparan chain(2) IEA Canis familiaris 63505 R-DDI-2090038 https://reactome.org/PathwayBrowser/#/R-DDI-2090038 NAGLU hydrolyses heparan chain(2) IEA Dictyostelium discoideum 63505 R-DME-1678854 https://reactome.org/PathwayBrowser/#/R-DME-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Drosophila melanogaster 63505 R-DME-2090038 https://reactome.org/PathwayBrowser/#/R-DME-2090038 NAGLU hydrolyses heparan chain(2) IEA Drosophila melanogaster 63505 R-DRE-1793209 https://reactome.org/PathwayBrowser/#/R-DRE-1793209 HYAL1 hydrolyses Chondroitin chains IEA Danio rerio 63505 R-GGA-1678854 https://reactome.org/PathwayBrowser/#/R-GGA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Gallus gallus 63505 R-GGA-1793209 https://reactome.org/PathwayBrowser/#/R-GGA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Gallus gallus 63505 R-GGA-2090038 https://reactome.org/PathwayBrowser/#/R-GGA-2090038 NAGLU hydrolyses heparan chain(2) IEA Gallus gallus 63505 R-HSA-1678854 https://reactome.org/PathwayBrowser/#/R-HSA-1678854 GUSB tetramer hydrolyses CS/HS precursor TAS Homo sapiens 63505 R-HSA-1793209 https://reactome.org/PathwayBrowser/#/R-HSA-1793209 HYAL1 hydrolyses Chondroitin chains TAS Homo sapiens 63505 R-HSA-2090038 https://reactome.org/PathwayBrowser/#/R-HSA-2090038 NAGLU hydrolyses heparan chain(2) TAS Homo sapiens 63505 R-HSA-9036070 https://reactome.org/PathwayBrowser/#/R-HSA-9036070 Defective GUSB does not hydrolyse CS/HS precursor TAS Homo sapiens 63505 R-MMU-1678854 https://reactome.org/PathwayBrowser/#/R-MMU-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Mus musculus 63505 R-MMU-1793209 https://reactome.org/PathwayBrowser/#/R-MMU-1793209 HYAL1 hydrolyses Chondroitin chains IEA Mus musculus 63505 R-MMU-2090038 https://reactome.org/PathwayBrowser/#/R-MMU-2090038 NAGLU hydrolyses heparan chain(2) IEA Mus musculus 63505 R-RNO-1678854 https://reactome.org/PathwayBrowser/#/R-RNO-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Rattus norvegicus 63505 R-RNO-1793209 https://reactome.org/PathwayBrowser/#/R-RNO-1793209 HYAL1 hydrolyses Chondroitin chains IEA Rattus norvegicus 63505 R-RNO-2090038 https://reactome.org/PathwayBrowser/#/R-RNO-2090038 NAGLU hydrolyses heparan chain(2) IEA Rattus norvegicus 63505 R-SSC-1678854 https://reactome.org/PathwayBrowser/#/R-SSC-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Sus scrofa 63505 R-SSC-1793209 https://reactome.org/PathwayBrowser/#/R-SSC-1793209 HYAL1 hydrolyses Chondroitin chains IEA Sus scrofa 63505 R-SSC-2090038 https://reactome.org/PathwayBrowser/#/R-SSC-2090038 NAGLU hydrolyses heparan chain(2) IEA Sus scrofa 63505 R-XTR-1678854 https://reactome.org/PathwayBrowser/#/R-XTR-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Xenopus tropicalis 63505 R-XTR-1793209 https://reactome.org/PathwayBrowser/#/R-XTR-1793209 HYAL1 hydrolyses Chondroitin chains IEA Xenopus tropicalis 63511 R-BTA-1793207 https://reactome.org/PathwayBrowser/#/R-BTA-1793207 ARSB hydrolyses C4S/C6S chains IEA Bos taurus 63511 R-BTA-1793209 https://reactome.org/PathwayBrowser/#/R-BTA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Bos taurus 63511 R-CEL-1793207 https://reactome.org/PathwayBrowser/#/R-CEL-1793207 ARSB hydrolyses C4S/C6S chains IEA Caenorhabditis elegans 63511 R-CEL-1793209 https://reactome.org/PathwayBrowser/#/R-CEL-1793209 HYAL1 hydrolyses Chondroitin chains IEA Caenorhabditis elegans 63511 R-CFA-1793207 https://reactome.org/PathwayBrowser/#/R-CFA-1793207 ARSB hydrolyses C4S/C6S chains IEA Canis familiaris 63511 R-CFA-1793209 https://reactome.org/PathwayBrowser/#/R-CFA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Canis familiaris 63511 R-DRE-1793209 https://reactome.org/PathwayBrowser/#/R-DRE-1793209 HYAL1 hydrolyses Chondroitin chains IEA Danio rerio 63511 R-GGA-1793207 https://reactome.org/PathwayBrowser/#/R-GGA-1793207 ARSB hydrolyses C4S/C6S chains IEA Gallus gallus 63511 R-GGA-1793209 https://reactome.org/PathwayBrowser/#/R-GGA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Gallus gallus 63511 R-HSA-1793207 https://reactome.org/PathwayBrowser/#/R-HSA-1793207 ARSB hydrolyses C4S/C6S chains TAS Homo sapiens 63511 R-HSA-1793209 https://reactome.org/PathwayBrowser/#/R-HSA-1793209 HYAL1 hydrolyses Chondroitin chains TAS Homo sapiens 63511 R-HSA-2318585 https://reactome.org/PathwayBrowser/#/R-HSA-2318585 Defective HYAL1 does not hydrolyse Chondroitin chains TAS Homo sapiens 63511 R-MMU-1793207 https://reactome.org/PathwayBrowser/#/R-MMU-1793207 ARSB hydrolyses C4S/C6S chains IEA Mus musculus 63511 R-MMU-1793209 https://reactome.org/PathwayBrowser/#/R-MMU-1793209 HYAL1 hydrolyses Chondroitin chains IEA Mus musculus 63511 R-RNO-1793207 https://reactome.org/PathwayBrowser/#/R-RNO-1793207 ARSB hydrolyses C4S/C6S chains IEA Rattus norvegicus 63511 R-RNO-1793209 https://reactome.org/PathwayBrowser/#/R-RNO-1793209 HYAL1 hydrolyses Chondroitin chains IEA Rattus norvegicus 63511 R-SSC-1793207 https://reactome.org/PathwayBrowser/#/R-SSC-1793207 ARSB hydrolyses C4S/C6S chains IEA Sus scrofa 63511 R-SSC-1793209 https://reactome.org/PathwayBrowser/#/R-SSC-1793209 HYAL1 hydrolyses Chondroitin chains IEA Sus scrofa 63511 R-XTR-1793209 https://reactome.org/PathwayBrowser/#/R-XTR-1793209 HYAL1 hydrolyses Chondroitin chains IEA Xenopus tropicalis 63512 R-BTA-1793207 https://reactome.org/PathwayBrowser/#/R-BTA-1793207 ARSB hydrolyses C4S/C6S chains IEA Bos taurus 63512 R-BTA-1793209 https://reactome.org/PathwayBrowser/#/R-BTA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Bos taurus 63512 R-CEL-1793207 https://reactome.org/PathwayBrowser/#/R-CEL-1793207 ARSB hydrolyses C4S/C6S chains IEA Caenorhabditis elegans 63512 R-CEL-1793209 https://reactome.org/PathwayBrowser/#/R-CEL-1793209 HYAL1 hydrolyses Chondroitin chains IEA Caenorhabditis elegans 63512 R-CFA-1793207 https://reactome.org/PathwayBrowser/#/R-CFA-1793207 ARSB hydrolyses C4S/C6S chains IEA Canis familiaris 63512 R-CFA-1793209 https://reactome.org/PathwayBrowser/#/R-CFA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Canis familiaris 63512 R-DRE-1793209 https://reactome.org/PathwayBrowser/#/R-DRE-1793209 HYAL1 hydrolyses Chondroitin chains IEA Danio rerio 63512 R-GGA-1793207 https://reactome.org/PathwayBrowser/#/R-GGA-1793207 ARSB hydrolyses C4S/C6S chains IEA Gallus gallus 63512 R-GGA-1793209 https://reactome.org/PathwayBrowser/#/R-GGA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Gallus gallus 63512 R-HSA-1793207 https://reactome.org/PathwayBrowser/#/R-HSA-1793207 ARSB hydrolyses C4S/C6S chains TAS Homo sapiens 63512 R-HSA-1793209 https://reactome.org/PathwayBrowser/#/R-HSA-1793209 HYAL1 hydrolyses Chondroitin chains TAS Homo sapiens 63512 R-HSA-2065233 https://reactome.org/PathwayBrowser/#/R-HSA-2065233 CS is cleaved from its proteoglycan TAS Homo sapiens 63512 R-HSA-2282889 https://reactome.org/PathwayBrowser/#/R-HSA-2282889 Defective ARSB does not hydrolyse C4S/C6S chains TAS Homo sapiens 63512 R-HSA-2318585 https://reactome.org/PathwayBrowser/#/R-HSA-2318585 Defective HYAL1 does not hydrolyse Chondroitin chains TAS Homo sapiens 63512 R-MMU-1793207 https://reactome.org/PathwayBrowser/#/R-MMU-1793207 ARSB hydrolyses C4S/C6S chains IEA Mus musculus 63512 R-MMU-1793209 https://reactome.org/PathwayBrowser/#/R-MMU-1793209 HYAL1 hydrolyses Chondroitin chains IEA Mus musculus 63512 R-RNO-1793207 https://reactome.org/PathwayBrowser/#/R-RNO-1793207 ARSB hydrolyses C4S/C6S chains IEA Rattus norvegicus 63512 R-RNO-1793209 https://reactome.org/PathwayBrowser/#/R-RNO-1793209 HYAL1 hydrolyses Chondroitin chains IEA Rattus norvegicus 63512 R-SSC-1793207 https://reactome.org/PathwayBrowser/#/R-SSC-1793207 ARSB hydrolyses C4S/C6S chains IEA Sus scrofa 63512 R-SSC-1793209 https://reactome.org/PathwayBrowser/#/R-SSC-1793209 HYAL1 hydrolyses Chondroitin chains IEA Sus scrofa 63512 R-XTR-1793209 https://reactome.org/PathwayBrowser/#/R-XTR-1793209 HYAL1 hydrolyses Chondroitin chains IEA Xenopus tropicalis 63513 R-BTA-1793207 https://reactome.org/PathwayBrowser/#/R-BTA-1793207 ARSB hydrolyses C4S/C6S chains IEA Bos taurus 63513 R-BTA-1793209 https://reactome.org/PathwayBrowser/#/R-BTA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Bos taurus 63513 R-CEL-1793207 https://reactome.org/PathwayBrowser/#/R-CEL-1793207 ARSB hydrolyses C4S/C6S chains IEA Caenorhabditis elegans 63513 R-CEL-1793209 https://reactome.org/PathwayBrowser/#/R-CEL-1793209 HYAL1 hydrolyses Chondroitin chains IEA Caenorhabditis elegans 63513 R-CFA-1793207 https://reactome.org/PathwayBrowser/#/R-CFA-1793207 ARSB hydrolyses C4S/C6S chains IEA Canis familiaris 63513 R-CFA-1793209 https://reactome.org/PathwayBrowser/#/R-CFA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Canis familiaris 63513 R-DRE-1793209 https://reactome.org/PathwayBrowser/#/R-DRE-1793209 HYAL1 hydrolyses Chondroitin chains IEA Danio rerio 63513 R-GGA-1793207 https://reactome.org/PathwayBrowser/#/R-GGA-1793207 ARSB hydrolyses C4S/C6S chains IEA Gallus gallus 63513 R-GGA-1793209 https://reactome.org/PathwayBrowser/#/R-GGA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Gallus gallus 63513 R-HSA-1793207 https://reactome.org/PathwayBrowser/#/R-HSA-1793207 ARSB hydrolyses C4S/C6S chains TAS Homo sapiens 63513 R-HSA-1793209 https://reactome.org/PathwayBrowser/#/R-HSA-1793209 HYAL1 hydrolyses Chondroitin chains TAS Homo sapiens 63513 R-HSA-2065233 https://reactome.org/PathwayBrowser/#/R-HSA-2065233 CS is cleaved from its proteoglycan TAS Homo sapiens 63513 R-HSA-2282889 https://reactome.org/PathwayBrowser/#/R-HSA-2282889 Defective ARSB does not hydrolyse C4S/C6S chains TAS Homo sapiens 63513 R-HSA-2318585 https://reactome.org/PathwayBrowser/#/R-HSA-2318585 Defective HYAL1 does not hydrolyse Chondroitin chains TAS Homo sapiens 63513 R-MMU-1793207 https://reactome.org/PathwayBrowser/#/R-MMU-1793207 ARSB hydrolyses C4S/C6S chains IEA Mus musculus 63513 R-MMU-1793209 https://reactome.org/PathwayBrowser/#/R-MMU-1793209 HYAL1 hydrolyses Chondroitin chains IEA Mus musculus 63513 R-RNO-1793207 https://reactome.org/PathwayBrowser/#/R-RNO-1793207 ARSB hydrolyses C4S/C6S chains IEA Rattus norvegicus 63513 R-RNO-1793209 https://reactome.org/PathwayBrowser/#/R-RNO-1793209 HYAL1 hydrolyses Chondroitin chains IEA Rattus norvegicus 63513 R-SSC-1793207 https://reactome.org/PathwayBrowser/#/R-SSC-1793207 ARSB hydrolyses C4S/C6S chains IEA Sus scrofa 63513 R-SSC-1793209 https://reactome.org/PathwayBrowser/#/R-SSC-1793209 HYAL1 hydrolyses Chondroitin chains IEA Sus scrofa 63513 R-XTR-1793209 https://reactome.org/PathwayBrowser/#/R-XTR-1793209 HYAL1 hydrolyses Chondroitin chains IEA Xenopus tropicalis 63515 R-BTA-1793209 https://reactome.org/PathwayBrowser/#/R-BTA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Bos taurus 63515 R-CEL-1793209 https://reactome.org/PathwayBrowser/#/R-CEL-1793209 HYAL1 hydrolyses Chondroitin chains IEA Caenorhabditis elegans 63515 R-CFA-1793209 https://reactome.org/PathwayBrowser/#/R-CFA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Canis familiaris 63515 R-DRE-1793209 https://reactome.org/PathwayBrowser/#/R-DRE-1793209 HYAL1 hydrolyses Chondroitin chains IEA Danio rerio 63515 R-GGA-1793209 https://reactome.org/PathwayBrowser/#/R-GGA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Gallus gallus 63515 R-HSA-1793209 https://reactome.org/PathwayBrowser/#/R-HSA-1793209 HYAL1 hydrolyses Chondroitin chains TAS Homo sapiens 63515 R-HSA-2318585 https://reactome.org/PathwayBrowser/#/R-HSA-2318585 Defective HYAL1 does not hydrolyse Chondroitin chains TAS Homo sapiens 63515 R-MMU-1793209 https://reactome.org/PathwayBrowser/#/R-MMU-1793209 HYAL1 hydrolyses Chondroitin chains IEA Mus musculus 63515 R-RNO-1793209 https://reactome.org/PathwayBrowser/#/R-RNO-1793209 HYAL1 hydrolyses Chondroitin chains IEA Rattus norvegicus 63515 R-SSC-1793209 https://reactome.org/PathwayBrowser/#/R-SSC-1793209 HYAL1 hydrolyses Chondroitin chains IEA Sus scrofa 63515 R-XTR-1793209 https://reactome.org/PathwayBrowser/#/R-XTR-1793209 HYAL1 hydrolyses Chondroitin chains IEA Xenopus tropicalis 63516 R-BTA-1793182 https://reactome.org/PathwayBrowser/#/R-BTA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Bos taurus 63516 R-BTA-2105001 https://reactome.org/PathwayBrowser/#/R-BTA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Bos taurus 63516 R-BTA-9638075 https://reactome.org/PathwayBrowser/#/R-BTA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Bos taurus 63516 R-CEL-2105001 https://reactome.org/PathwayBrowser/#/R-CEL-2105001 HEXA cleaves the terminal GalNAc from DS IEA Caenorhabditis elegans 63516 R-CEL-9638075 https://reactome.org/PathwayBrowser/#/R-CEL-9638075 HEXB cleaves the terminal GalNAc from DS IEA Caenorhabditis elegans 63516 R-CFA-1793182 https://reactome.org/PathwayBrowser/#/R-CFA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Canis familiaris 63516 R-CFA-2105001 https://reactome.org/PathwayBrowser/#/R-CFA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Canis familiaris 63516 R-CFA-9638075 https://reactome.org/PathwayBrowser/#/R-CFA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Canis familiaris 63516 R-DDI-2105001 https://reactome.org/PathwayBrowser/#/R-DDI-2105001 HEXA cleaves the terminal GalNAc from DS IEA Dictyostelium discoideum 63516 R-DDI-9638075 https://reactome.org/PathwayBrowser/#/R-DDI-9638075 HEXB cleaves the terminal GalNAc from DS IEA Dictyostelium discoideum 63516 R-DME-1793182 https://reactome.org/PathwayBrowser/#/R-DME-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Drosophila melanogaster 63516 R-DME-2105001 https://reactome.org/PathwayBrowser/#/R-DME-2105001 HEXA cleaves the terminal GalNAc from DS IEA Drosophila melanogaster 63516 R-DME-9638075 https://reactome.org/PathwayBrowser/#/R-DME-9638075 HEXB cleaves the terminal GalNAc from DS IEA Drosophila melanogaster 63516 R-DRE-1793182 https://reactome.org/PathwayBrowser/#/R-DRE-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Danio rerio 63516 R-GGA-1793182 https://reactome.org/PathwayBrowser/#/R-GGA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Gallus gallus 63516 R-GGA-2105001 https://reactome.org/PathwayBrowser/#/R-GGA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Gallus gallus 63516 R-GGA-9638075 https://reactome.org/PathwayBrowser/#/R-GGA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Gallus gallus 63516 R-HSA-1793182 https://reactome.org/PathwayBrowser/#/R-HSA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) TAS Homo sapiens 63516 R-HSA-2105001 https://reactome.org/PathwayBrowser/#/R-HSA-2105001 HEXA cleaves the terminal GalNAc from DS TAS Homo sapiens 63516 R-HSA-3656259 https://reactome.org/PathwayBrowser/#/R-HSA-3656259 Defective HEXA does not cleave the terminal GalNAc from DS TAS Homo sapiens 63516 R-HSA-3662344 https://reactome.org/PathwayBrowser/#/R-HSA-3662344 Defective HEXB does not cleave the terminal GalNAc from DS TAS Homo sapiens 63516 R-HSA-9638075 https://reactome.org/PathwayBrowser/#/R-HSA-9638075 HEXB cleaves the terminal GalNAc from DS TAS Homo sapiens 63516 R-MMU-1793182 https://reactome.org/PathwayBrowser/#/R-MMU-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Mus musculus 63516 R-MMU-2105001 https://reactome.org/PathwayBrowser/#/R-MMU-2105001 HEXA cleaves the terminal GalNAc from DS IEA Mus musculus 63516 R-MMU-9638075 https://reactome.org/PathwayBrowser/#/R-MMU-9638075 HEXB cleaves the terminal GalNAc from DS IEA Mus musculus 63516 R-RNO-1793182 https://reactome.org/PathwayBrowser/#/R-RNO-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Rattus norvegicus 63516 R-RNO-2105001 https://reactome.org/PathwayBrowser/#/R-RNO-2105001 HEXA cleaves the terminal GalNAc from DS IEA Rattus norvegicus 63516 R-RNO-9638075 https://reactome.org/PathwayBrowser/#/R-RNO-9638075 HEXB cleaves the terminal GalNAc from DS IEA Rattus norvegicus 63516 R-SSC-1793182 https://reactome.org/PathwayBrowser/#/R-SSC-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Sus scrofa 63516 R-SSC-2105001 https://reactome.org/PathwayBrowser/#/R-SSC-2105001 HEXA cleaves the terminal GalNAc from DS IEA Sus scrofa 63516 R-SSC-9638075 https://reactome.org/PathwayBrowser/#/R-SSC-9638075 HEXB cleaves the terminal GalNAc from DS IEA Sus scrofa 63516 R-XTR-1793182 https://reactome.org/PathwayBrowser/#/R-XTR-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Xenopus tropicalis 63516 R-XTR-9638075 https://reactome.org/PathwayBrowser/#/R-XTR-9638075 HEXB cleaves the terminal GalNAc from DS IEA Xenopus tropicalis 63517 R-BTA-1606789 https://reactome.org/PathwayBrowser/#/R-BTA-1606789 ARSB hydrolyses DS IEA Bos taurus 63517 R-BTA-1793182 https://reactome.org/PathwayBrowser/#/R-BTA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Bos taurus 63517 R-CEL-1606789 https://reactome.org/PathwayBrowser/#/R-CEL-1606789 ARSB hydrolyses DS IEA Caenorhabditis elegans 63517 R-CFA-1606789 https://reactome.org/PathwayBrowser/#/R-CFA-1606789 ARSB hydrolyses DS IEA Canis familiaris 63517 R-CFA-1793182 https://reactome.org/PathwayBrowser/#/R-CFA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Canis familiaris 63517 R-DME-1793182 https://reactome.org/PathwayBrowser/#/R-DME-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Drosophila melanogaster 63517 R-DRE-1793182 https://reactome.org/PathwayBrowser/#/R-DRE-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Danio rerio 63517 R-GGA-1606789 https://reactome.org/PathwayBrowser/#/R-GGA-1606789 ARSB hydrolyses DS IEA Gallus gallus 63517 R-GGA-1793182 https://reactome.org/PathwayBrowser/#/R-GGA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Gallus gallus 63517 R-HSA-1606789 https://reactome.org/PathwayBrowser/#/R-HSA-1606789 ARSB hydrolyses DS TAS Homo sapiens 63517 R-HSA-1793182 https://reactome.org/PathwayBrowser/#/R-HSA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) TAS Homo sapiens 63517 R-HSA-2262743 https://reactome.org/PathwayBrowser/#/R-HSA-2262743 Defective IDS does not hydrolyse dermatan sulfate (Chebi:63517 chain) TAS Homo sapiens 63517 R-MMU-1606789 https://reactome.org/PathwayBrowser/#/R-MMU-1606789 ARSB hydrolyses DS IEA Mus musculus 63517 R-MMU-1793182 https://reactome.org/PathwayBrowser/#/R-MMU-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Mus musculus 63517 R-RNO-1606789 https://reactome.org/PathwayBrowser/#/R-RNO-1606789 ARSB hydrolyses DS IEA Rattus norvegicus 63517 R-RNO-1793182 https://reactome.org/PathwayBrowser/#/R-RNO-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Rattus norvegicus 63517 R-SSC-1606789 https://reactome.org/PathwayBrowser/#/R-SSC-1606789 ARSB hydrolyses DS IEA Sus scrofa 63517 R-SSC-1793182 https://reactome.org/PathwayBrowser/#/R-SSC-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Sus scrofa 63517 R-XTR-1793182 https://reactome.org/PathwayBrowser/#/R-XTR-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Xenopus tropicalis 63519 R-BTA-1606789 https://reactome.org/PathwayBrowser/#/R-BTA-1606789 ARSB hydrolyses DS IEA Bos taurus 63519 R-CEL-1606789 https://reactome.org/PathwayBrowser/#/R-CEL-1606789 ARSB hydrolyses DS IEA Caenorhabditis elegans 63519 R-CFA-1606789 https://reactome.org/PathwayBrowser/#/R-CFA-1606789 ARSB hydrolyses DS IEA Canis familiaris 63519 R-GGA-1606789 https://reactome.org/PathwayBrowser/#/R-GGA-1606789 ARSB hydrolyses DS IEA Gallus gallus 63519 R-HSA-1606789 https://reactome.org/PathwayBrowser/#/R-HSA-1606789 ARSB hydrolyses DS TAS Homo sapiens 63519 R-HSA-1793176 https://reactome.org/PathwayBrowser/#/R-HSA-1793176 DS is cleaved from its proteoglycan TAS Homo sapiens 63519 R-HSA-9036065 https://reactome.org/PathwayBrowser/#/R-HSA-9036065 Defective ARSB does not hydrolyse DS TAS Homo sapiens 63519 R-MMU-1606789 https://reactome.org/PathwayBrowser/#/R-MMU-1606789 ARSB hydrolyses DS IEA Mus musculus 63519 R-RNO-1606789 https://reactome.org/PathwayBrowser/#/R-RNO-1606789 ARSB hydrolyses DS IEA Rattus norvegicus 63519 R-SSC-1606789 https://reactome.org/PathwayBrowser/#/R-SSC-1606789 ARSB hydrolyses DS IEA Sus scrofa 63528 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 63528 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 63528 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 63528 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 63528 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 63528 R-BTA-109759 https://reactome.org/PathwayBrowser/#/R-BTA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Bos taurus 63528 R-BTA-73605 https://reactome.org/PathwayBrowser/#/R-BTA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Bos taurus 63528 R-BTA-73632 https://reactome.org/PathwayBrowser/#/R-BTA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Bos taurus 63528 R-BTA-73635 https://reactome.org/PathwayBrowser/#/R-BTA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Bos taurus 63528 R-BTA-75126 https://reactome.org/PathwayBrowser/#/R-BTA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Bos taurus 63528 R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 63528 R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 63528 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 63528 R-CEL-73605 https://reactome.org/PathwayBrowser/#/R-CEL-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Caenorhabditis elegans 63528 R-CEL-73632 https://reactome.org/PathwayBrowser/#/R-CEL-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Caenorhabditis elegans 63528 R-CEL-73635 https://reactome.org/PathwayBrowser/#/R-CEL-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Caenorhabditis elegans 63528 R-CEL-75126 https://reactome.org/PathwayBrowser/#/R-CEL-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Caenorhabditis elegans 63528 R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 63528 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 63528 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 63528 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 63528 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 63528 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 63528 R-CFA-109759 https://reactome.org/PathwayBrowser/#/R-CFA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Canis familiaris 63528 R-CFA-73605 https://reactome.org/PathwayBrowser/#/R-CFA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Canis familiaris 63528 R-CFA-73632 https://reactome.org/PathwayBrowser/#/R-CFA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Canis familiaris 63528 R-CFA-73635 https://reactome.org/PathwayBrowser/#/R-CFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Canis familiaris 63528 R-CFA-75126 https://reactome.org/PathwayBrowser/#/R-CFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Canis familiaris 63528 R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 63528 R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 63528 R-DDI-73632 https://reactome.org/PathwayBrowser/#/R-DDI-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Dictyostelium discoideum 63528 R-DDI-73635 https://reactome.org/PathwayBrowser/#/R-DDI-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Dictyostelium discoideum 63528 R-DDI-75126 https://reactome.org/PathwayBrowser/#/R-DDI-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Dictyostelium discoideum 63528 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 63528 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 63528 R-DME-109759 https://reactome.org/PathwayBrowser/#/R-DME-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Drosophila melanogaster 63528 R-DME-73605 https://reactome.org/PathwayBrowser/#/R-DME-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Drosophila melanogaster 63528 R-DME-73635 https://reactome.org/PathwayBrowser/#/R-DME-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Drosophila melanogaster 63528 R-DME-75126 https://reactome.org/PathwayBrowser/#/R-DME-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Drosophila melanogaster 63528 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 63528 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 63528 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 63528 R-DRE-73605 https://reactome.org/PathwayBrowser/#/R-DRE-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Danio rerio 63528 R-DRE-73632 https://reactome.org/PathwayBrowser/#/R-DRE-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Danio rerio 63528 R-DRE-73635 https://reactome.org/PathwayBrowser/#/R-DRE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Danio rerio 63528 R-DRE-75126 https://reactome.org/PathwayBrowser/#/R-DRE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Danio rerio 63528 R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 63528 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 63528 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 63528 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 63528 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 63528 R-GGA-109759 https://reactome.org/PathwayBrowser/#/R-GGA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Gallus gallus 63528 R-GGA-73632 https://reactome.org/PathwayBrowser/#/R-GGA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Gallus gallus 63528 R-GGA-73635 https://reactome.org/PathwayBrowser/#/R-GGA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Gallus gallus 63528 R-GGA-75126 https://reactome.org/PathwayBrowser/#/R-GGA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Gallus gallus 63528 R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 63528 R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 63528 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 63528 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 63528 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 63528 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 63528 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 63528 R-HSA-109759 https://reactome.org/PathwayBrowser/#/R-HSA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] TAS Homo sapiens 63528 R-HSA-3245943 https://reactome.org/PathwayBrowser/#/R-HSA-3245943 Viral DNA cleavage by TREX1 TAS Homo sapiens 63528 R-HSA-73605 https://reactome.org/PathwayBrowser/#/R-HSA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate TAS Homo sapiens 63528 R-HSA-73632 https://reactome.org/PathwayBrowser/#/R-HSA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] TAS Homo sapiens 63528 R-HSA-73635 https://reactome.org/PathwayBrowser/#/R-HSA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] TAS Homo sapiens 63528 R-HSA-75126 https://reactome.org/PathwayBrowser/#/R-HSA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] TAS Homo sapiens 63528 R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 63528 R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 63528 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 63528 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 63528 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 63528 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 63528 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 63528 R-MMU-109759 https://reactome.org/PathwayBrowser/#/R-MMU-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Mus musculus 63528 R-MMU-73605 https://reactome.org/PathwayBrowser/#/R-MMU-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Mus musculus 63528 R-MMU-73632 https://reactome.org/PathwayBrowser/#/R-MMU-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Mus musculus 63528 R-MMU-73635 https://reactome.org/PathwayBrowser/#/R-MMU-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Mus musculus 63528 R-MMU-75126 https://reactome.org/PathwayBrowser/#/R-MMU-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Mus musculus 63528 R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 63528 R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 63528 R-PFA-73605 https://reactome.org/PathwayBrowser/#/R-PFA-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Plasmodium falciparum 63528 R-PFA-73635 https://reactome.org/PathwayBrowser/#/R-PFA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Plasmodium falciparum 63528 R-PFA-75126 https://reactome.org/PathwayBrowser/#/R-PFA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Plasmodium falciparum 63528 R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 63528 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 63528 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 63528 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 63528 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 63528 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 63528 R-RNO-109759 https://reactome.org/PathwayBrowser/#/R-RNO-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Rattus norvegicus 63528 R-RNO-73605 https://reactome.org/PathwayBrowser/#/R-RNO-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Rattus norvegicus 63528 R-RNO-73632 https://reactome.org/PathwayBrowser/#/R-RNO-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Rattus norvegicus 63528 R-RNO-73635 https://reactome.org/PathwayBrowser/#/R-RNO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Rattus norvegicus 63528 R-RNO-75126 https://reactome.org/PathwayBrowser/#/R-RNO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Rattus norvegicus 63528 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 63528 R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 63528 R-SCE-73605 https://reactome.org/PathwayBrowser/#/R-SCE-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Saccharomyces cerevisiae 63528 R-SCE-73635 https://reactome.org/PathwayBrowser/#/R-SCE-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Saccharomyces cerevisiae 63528 R-SCE-75126 https://reactome.org/PathwayBrowser/#/R-SCE-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Saccharomyces cerevisiae 63528 R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 63528 R-SPO-73605 https://reactome.org/PathwayBrowser/#/R-SPO-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Schizosaccharomyces pombe 63528 R-SPO-73635 https://reactome.org/PathwayBrowser/#/R-SPO-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Schizosaccharomyces pombe 63528 R-SPO-75126 https://reactome.org/PathwayBrowser/#/R-SPO-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Schizosaccharomyces pombe 63528 R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 63528 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 63528 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 63528 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 63528 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 63528 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 63528 R-SSC-109759 https://reactome.org/PathwayBrowser/#/R-SSC-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Sus scrofa 63528 R-SSC-73605 https://reactome.org/PathwayBrowser/#/R-SSC-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Sus scrofa 63528 R-SSC-73632 https://reactome.org/PathwayBrowser/#/R-SSC-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Sus scrofa 63528 R-SSC-73635 https://reactome.org/PathwayBrowser/#/R-SSC-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Sus scrofa 63528 R-SSC-75126 https://reactome.org/PathwayBrowser/#/R-SSC-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Sus scrofa 63528 R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 63528 R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 63528 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 63528 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 63528 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 63528 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 63528 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 63528 R-XTR-109759 https://reactome.org/PathwayBrowser/#/R-XTR-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Xenopus tropicalis 63528 R-XTR-73605 https://reactome.org/PathwayBrowser/#/R-XTR-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Xenopus tropicalis 63528 R-XTR-73632 https://reactome.org/PathwayBrowser/#/R-XTR-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Xenopus tropicalis 63528 R-XTR-73635 https://reactome.org/PathwayBrowser/#/R-XTR-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Xenopus tropicalis 63528 R-XTR-75126 https://reactome.org/PathwayBrowser/#/R-XTR-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Xenopus tropicalis 63528 R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 63528 R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 63539 R-BTA-2046089 https://reactome.org/PathwayBrowser/#/R-BTA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Bos taurus 63539 R-BTA-2046100 https://reactome.org/PathwayBrowser/#/R-BTA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Bos taurus 63539 R-CEL-2046089 https://reactome.org/PathwayBrowser/#/R-CEL-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Caenorhabditis elegans 63539 R-CFA-2046089 https://reactome.org/PathwayBrowser/#/R-CFA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Canis familiaris 63539 R-CFA-2046100 https://reactome.org/PathwayBrowser/#/R-CFA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Canis familiaris 63539 R-DDI-2046100 https://reactome.org/PathwayBrowser/#/R-DDI-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Dictyostelium discoideum 63539 R-DME-2046100 https://reactome.org/PathwayBrowser/#/R-DME-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Drosophila melanogaster 63539 R-DRE-2046100 https://reactome.org/PathwayBrowser/#/R-DRE-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Danio rerio 63539 R-GGA-2046089 https://reactome.org/PathwayBrowser/#/R-GGA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Gallus gallus 63539 R-GGA-2046100 https://reactome.org/PathwayBrowser/#/R-GGA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Gallus gallus 63539 R-HSA-2046089 https://reactome.org/PathwayBrowser/#/R-HSA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA TAS Homo sapiens 63539 R-HSA-2046100 https://reactome.org/PathwayBrowser/#/R-HSA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA TAS Homo sapiens 63539 R-MMU-2046089 https://reactome.org/PathwayBrowser/#/R-MMU-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Mus musculus 63539 R-MMU-2046100 https://reactome.org/PathwayBrowser/#/R-MMU-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Mus musculus 63539 R-RNO-2046089 https://reactome.org/PathwayBrowser/#/R-RNO-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Rattus norvegicus 63539 R-RNO-2046100 https://reactome.org/PathwayBrowser/#/R-RNO-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Rattus norvegicus 63539 R-SSC-2046089 https://reactome.org/PathwayBrowser/#/R-SSC-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Sus scrofa 63539 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa 63539 R-XTR-2046089 https://reactome.org/PathwayBrowser/#/R-XTR-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Xenopus tropicalis 63539 R-XTR-2046100 https://reactome.org/PathwayBrowser/#/R-XTR-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Xenopus tropicalis 63540 R-BTA-2046087 https://reactome.org/PathwayBrowser/#/R-BTA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Bos taurus 63540 R-BTA-2066787 https://reactome.org/PathwayBrowser/#/R-BTA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Bos taurus 63540 R-CEL-2046087 https://reactome.org/PathwayBrowser/#/R-CEL-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Caenorhabditis elegans 63540 R-CEL-2066787 https://reactome.org/PathwayBrowser/#/R-CEL-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Caenorhabditis elegans 63540 R-CFA-2046087 https://reactome.org/PathwayBrowser/#/R-CFA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Canis familiaris 63540 R-CFA-2066787 https://reactome.org/PathwayBrowser/#/R-CFA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Canis familiaris 63540 R-DDI-2046087 https://reactome.org/PathwayBrowser/#/R-DDI-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Dictyostelium discoideum 63540 R-DDI-2066787 https://reactome.org/PathwayBrowser/#/R-DDI-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Dictyostelium discoideum 63540 R-DME-2046087 https://reactome.org/PathwayBrowser/#/R-DME-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Drosophila melanogaster 63540 R-DME-2066787 https://reactome.org/PathwayBrowser/#/R-DME-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Drosophila melanogaster 63540 R-DRE-2066787 https://reactome.org/PathwayBrowser/#/R-DRE-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Danio rerio 63540 R-GGA-2066787 https://reactome.org/PathwayBrowser/#/R-GGA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Gallus gallus 63540 R-HSA-2046087 https://reactome.org/PathwayBrowser/#/R-HSA-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes TAS Homo sapiens 63540 R-HSA-2046099 https://reactome.org/PathwayBrowser/#/R-HSA-2046099 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA IEA Homo sapiens 63540 R-HSA-2066787 https://reactome.org/PathwayBrowser/#/R-HSA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA TAS Homo sapiens 63540 R-MMU-2046087 https://reactome.org/PathwayBrowser/#/R-MMU-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Mus musculus 63540 R-MMU-2066787 https://reactome.org/PathwayBrowser/#/R-MMU-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Mus musculus 63540 R-RNO-2046087 https://reactome.org/PathwayBrowser/#/R-RNO-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Rattus norvegicus 63540 R-RNO-2046091 https://reactome.org/PathwayBrowser/#/R-RNO-2046091 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA TAS Rattus norvegicus 63540 R-RNO-2066787 https://reactome.org/PathwayBrowser/#/R-RNO-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Rattus norvegicus 63540 R-SCE-2046087 https://reactome.org/PathwayBrowser/#/R-SCE-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Saccharomyces cerevisiae 63540 R-SSC-2046087 https://reactome.org/PathwayBrowser/#/R-SSC-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Sus scrofa 63540 R-SSC-2066787 https://reactome.org/PathwayBrowser/#/R-SSC-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Sus scrofa 63540 R-XTR-2046087 https://reactome.org/PathwayBrowser/#/R-XTR-2046087 Translocation of tetracosahexaenoyl-CoA to peroxisomes IEA Xenopus tropicalis 63540 R-XTR-2066787 https://reactome.org/PathwayBrowser/#/R-XTR-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Xenopus tropicalis 63541 R-BTA-2046090 https://reactome.org/PathwayBrowser/#/R-BTA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 63541 R-BTA-2046100 https://reactome.org/PathwayBrowser/#/R-BTA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Bos taurus 63541 R-CFA-2046090 https://reactome.org/PathwayBrowser/#/R-CFA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 63541 R-CFA-2046100 https://reactome.org/PathwayBrowser/#/R-CFA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Canis familiaris 63541 R-DDI-2046090 https://reactome.org/PathwayBrowser/#/R-DDI-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Dictyostelium discoideum 63541 R-DDI-2046100 https://reactome.org/PathwayBrowser/#/R-DDI-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Dictyostelium discoideum 63541 R-DME-2046090 https://reactome.org/PathwayBrowser/#/R-DME-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Drosophila melanogaster 63541 R-DME-2046100 https://reactome.org/PathwayBrowser/#/R-DME-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Drosophila melanogaster 63541 R-DRE-2046090 https://reactome.org/PathwayBrowser/#/R-DRE-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 63541 R-DRE-2046100 https://reactome.org/PathwayBrowser/#/R-DRE-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Danio rerio 63541 R-GGA-2046090 https://reactome.org/PathwayBrowser/#/R-GGA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 63541 R-GGA-2046100 https://reactome.org/PathwayBrowser/#/R-GGA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Gallus gallus 63541 R-HSA-2046090 https://reactome.org/PathwayBrowser/#/R-HSA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 63541 R-HSA-2046100 https://reactome.org/PathwayBrowser/#/R-HSA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA TAS Homo sapiens 63541 R-MMU-2046090 https://reactome.org/PathwayBrowser/#/R-MMU-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 63541 R-MMU-2046100 https://reactome.org/PathwayBrowser/#/R-MMU-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Mus musculus 63541 R-RNO-2046090 https://reactome.org/PathwayBrowser/#/R-RNO-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 63541 R-RNO-2046100 https://reactome.org/PathwayBrowser/#/R-RNO-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Rattus norvegicus 63541 R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 63541 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa 63541 R-XTR-2046090 https://reactome.org/PathwayBrowser/#/R-XTR-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Xenopus tropicalis 63541 R-XTR-2046100 https://reactome.org/PathwayBrowser/#/R-XTR-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Xenopus tropicalis 63542 R-BTA-2046088 https://reactome.org/PathwayBrowser/#/R-BTA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Bos taurus 63542 R-BTA-2046089 https://reactome.org/PathwayBrowser/#/R-BTA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Bos taurus 63542 R-CEL-2046088 https://reactome.org/PathwayBrowser/#/R-CEL-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Caenorhabditis elegans 63542 R-CEL-2046089 https://reactome.org/PathwayBrowser/#/R-CEL-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Caenorhabditis elegans 63542 R-CFA-2046088 https://reactome.org/PathwayBrowser/#/R-CFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Canis familiaris 63542 R-CFA-2046089 https://reactome.org/PathwayBrowser/#/R-CFA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Canis familiaris 63542 R-DDI-2046088 https://reactome.org/PathwayBrowser/#/R-DDI-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Dictyostelium discoideum 63542 R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster 63542 R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio 63542 R-GGA-2046088 https://reactome.org/PathwayBrowser/#/R-GGA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Gallus gallus 63542 R-GGA-2046089 https://reactome.org/PathwayBrowser/#/R-GGA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Gallus gallus 63542 R-HSA-2046088 https://reactome.org/PathwayBrowser/#/R-HSA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA TAS Homo sapiens 63542 R-HSA-2046089 https://reactome.org/PathwayBrowser/#/R-HSA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA TAS Homo sapiens 63542 R-MMU-2046088 https://reactome.org/PathwayBrowser/#/R-MMU-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Mus musculus 63542 R-MMU-2046089 https://reactome.org/PathwayBrowser/#/R-MMU-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Mus musculus 63542 R-PFA-2046088 https://reactome.org/PathwayBrowser/#/R-PFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Plasmodium falciparum 63542 R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus 63542 R-RNO-2046089 https://reactome.org/PathwayBrowser/#/R-RNO-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Rattus norvegicus 63542 R-SCE-2046088 https://reactome.org/PathwayBrowser/#/R-SCE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Saccharomyces cerevisiae 63542 R-SPO-2046088 https://reactome.org/PathwayBrowser/#/R-SPO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Schizosaccharomyces pombe 63542 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa 63542 R-SSC-2046089 https://reactome.org/PathwayBrowser/#/R-SSC-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Sus scrofa 63542 R-XTR-2046088 https://reactome.org/PathwayBrowser/#/R-XTR-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Xenopus tropicalis 63542 R-XTR-2046089 https://reactome.org/PathwayBrowser/#/R-XTR-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Xenopus tropicalis 63543 R-BTA-2046090 https://reactome.org/PathwayBrowser/#/R-BTA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 63543 R-CFA-2046090 https://reactome.org/PathwayBrowser/#/R-CFA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 63543 R-DDI-2046090 https://reactome.org/PathwayBrowser/#/R-DDI-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Dictyostelium discoideum 63543 R-DME-2046090 https://reactome.org/PathwayBrowser/#/R-DME-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Drosophila melanogaster 63543 R-DRE-2046090 https://reactome.org/PathwayBrowser/#/R-DRE-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 63543 R-GGA-2046090 https://reactome.org/PathwayBrowser/#/R-GGA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 63543 R-HSA-2046090 https://reactome.org/PathwayBrowser/#/R-HSA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 63543 R-HSA-2046099 https://reactome.org/PathwayBrowser/#/R-HSA-2046099 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA IEA Homo sapiens 63543 R-MMU-2046090 https://reactome.org/PathwayBrowser/#/R-MMU-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 63543 R-RNO-2046090 https://reactome.org/PathwayBrowser/#/R-RNO-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 63543 R-RNO-2046091 https://reactome.org/PathwayBrowser/#/R-RNO-2046091 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA TAS Rattus norvegicus 63543 R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 63543 R-XTR-2046090 https://reactome.org/PathwayBrowser/#/R-XTR-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Xenopus tropicalis 63544 R-BTA-2046083 https://reactome.org/PathwayBrowser/#/R-BTA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Bos taurus 63544 R-BTA-2046095 https://reactome.org/PathwayBrowser/#/R-BTA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Bos taurus 63544 R-CFA-2046083 https://reactome.org/PathwayBrowser/#/R-CFA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Canis familiaris 63544 R-CFA-2046095 https://reactome.org/PathwayBrowser/#/R-CFA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Canis familiaris 63544 R-DDI-2046083 https://reactome.org/PathwayBrowser/#/R-DDI-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Dictyostelium discoideum 63544 R-DDI-2046095 https://reactome.org/PathwayBrowser/#/R-DDI-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Dictyostelium discoideum 63544 R-DME-2046083 https://reactome.org/PathwayBrowser/#/R-DME-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Drosophila melanogaster 63544 R-DME-2046095 https://reactome.org/PathwayBrowser/#/R-DME-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Drosophila melanogaster 63544 R-DRE-2046083 https://reactome.org/PathwayBrowser/#/R-DRE-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Danio rerio 63544 R-DRE-2046095 https://reactome.org/PathwayBrowser/#/R-DRE-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Danio rerio 63544 R-GGA-2046083 https://reactome.org/PathwayBrowser/#/R-GGA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Gallus gallus 63544 R-GGA-2046095 https://reactome.org/PathwayBrowser/#/R-GGA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Gallus gallus 63544 R-HSA-2046083 https://reactome.org/PathwayBrowser/#/R-HSA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA TAS Homo sapiens 63544 R-HSA-2046095 https://reactome.org/PathwayBrowser/#/R-HSA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA TAS Homo sapiens 63544 R-MMU-2046083 https://reactome.org/PathwayBrowser/#/R-MMU-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Mus musculus 63544 R-MMU-2046095 https://reactome.org/PathwayBrowser/#/R-MMU-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Mus musculus 63544 R-RNO-2046083 https://reactome.org/PathwayBrowser/#/R-RNO-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Rattus norvegicus 63544 R-RNO-2046095 https://reactome.org/PathwayBrowser/#/R-RNO-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Rattus norvegicus 63544 R-SSC-2046083 https://reactome.org/PathwayBrowser/#/R-SSC-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Sus scrofa 63544 R-SSC-2046095 https://reactome.org/PathwayBrowser/#/R-SSC-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Sus scrofa 63544 R-XTR-2046083 https://reactome.org/PathwayBrowser/#/R-XTR-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Xenopus tropicalis 63544 R-XTR-2046095 https://reactome.org/PathwayBrowser/#/R-XTR-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Xenopus tropicalis 63545 R-BTA-2046084 https://reactome.org/PathwayBrowser/#/R-BTA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Bos taurus 63545 R-BTA-2046088 https://reactome.org/PathwayBrowser/#/R-BTA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Bos taurus 63545 R-CEL-2046084 https://reactome.org/PathwayBrowser/#/R-CEL-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Caenorhabditis elegans 63545 R-CEL-2046088 https://reactome.org/PathwayBrowser/#/R-CEL-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Caenorhabditis elegans 63545 R-CFA-2046084 https://reactome.org/PathwayBrowser/#/R-CFA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Canis familiaris 63545 R-CFA-2046088 https://reactome.org/PathwayBrowser/#/R-CFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Canis familiaris 63545 R-DDI-2046088 https://reactome.org/PathwayBrowser/#/R-DDI-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Dictyostelium discoideum 63545 R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster 63545 R-DRE-2046084 https://reactome.org/PathwayBrowser/#/R-DRE-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Danio rerio 63545 R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio 63545 R-GGA-2046084 https://reactome.org/PathwayBrowser/#/R-GGA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Gallus gallus 63545 R-GGA-2046088 https://reactome.org/PathwayBrowser/#/R-GGA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Gallus gallus 63545 R-HSA-2046084 https://reactome.org/PathwayBrowser/#/R-HSA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA TAS Homo sapiens 63545 R-HSA-2046088 https://reactome.org/PathwayBrowser/#/R-HSA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA TAS Homo sapiens 63545 R-MMU-2046084 https://reactome.org/PathwayBrowser/#/R-MMU-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Mus musculus 63545 R-MMU-2046088 https://reactome.org/PathwayBrowser/#/R-MMU-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Mus musculus 63545 R-PFA-2046088 https://reactome.org/PathwayBrowser/#/R-PFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Plasmodium falciparum 63545 R-RNO-2046084 https://reactome.org/PathwayBrowser/#/R-RNO-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Rattus norvegicus 63545 R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus 63545 R-SCE-2046088 https://reactome.org/PathwayBrowser/#/R-SCE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Saccharomyces cerevisiae 63545 R-SPO-2046088 https://reactome.org/PathwayBrowser/#/R-SPO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Schizosaccharomyces pombe 63545 R-SSC-2046084 https://reactome.org/PathwayBrowser/#/R-SSC-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Sus scrofa 63545 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa 63545 R-XTR-2046088 https://reactome.org/PathwayBrowser/#/R-XTR-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Xenopus tropicalis 63546 R-BTA-2046093 https://reactome.org/PathwayBrowser/#/R-BTA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Bos taurus 63546 R-BTA-2046097 https://reactome.org/PathwayBrowser/#/R-BTA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 63546 R-CEL-2046093 https://reactome.org/PathwayBrowser/#/R-CEL-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Caenorhabditis elegans 63546 R-CEL-2046097 https://reactome.org/PathwayBrowser/#/R-CEL-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Caenorhabditis elegans 63546 R-CFA-2046093 https://reactome.org/PathwayBrowser/#/R-CFA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Canis familiaris 63546 R-CFA-2046097 https://reactome.org/PathwayBrowser/#/R-CFA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 63546 R-DDI-2046093 https://reactome.org/PathwayBrowser/#/R-DDI-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Dictyostelium discoideum 63546 R-DME-2046093 https://reactome.org/PathwayBrowser/#/R-DME-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Drosophila melanogaster 63546 R-DRE-2046097 https://reactome.org/PathwayBrowser/#/R-DRE-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 63546 R-GGA-2046097 https://reactome.org/PathwayBrowser/#/R-GGA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 63546 R-HSA-2046093 https://reactome.org/PathwayBrowser/#/R-HSA-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes TAS Homo sapiens 63546 R-HSA-2046097 https://reactome.org/PathwayBrowser/#/R-HSA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 63546 R-HSA-2046101 https://reactome.org/PathwayBrowser/#/R-HSA-2046101 Peroxisomal beta-oxidation of tetracosapentaenoyl-CoA to Docosapentaenoyl-CoA TAS Homo sapiens 63546 R-MMU-2046093 https://reactome.org/PathwayBrowser/#/R-MMU-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Mus musculus 63546 R-MMU-2046097 https://reactome.org/PathwayBrowser/#/R-MMU-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 63546 R-RNO-2046093 https://reactome.org/PathwayBrowser/#/R-RNO-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Rattus norvegicus 63546 R-RNO-2046097 https://reactome.org/PathwayBrowser/#/R-RNO-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 63546 R-SCE-2046093 https://reactome.org/PathwayBrowser/#/R-SCE-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Saccharomyces cerevisiae 63546 R-SSC-2046093 https://reactome.org/PathwayBrowser/#/R-SSC-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Sus scrofa 63546 R-SSC-2046097 https://reactome.org/PathwayBrowser/#/R-SSC-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 63546 R-XTR-2046093 https://reactome.org/PathwayBrowser/#/R-XTR-2046093 Translocation of tetracosapentaenoyl-CoA to peroxisomes IEA Xenopus tropicalis 63548 R-BTA-2046095 https://reactome.org/PathwayBrowser/#/R-BTA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Bos taurus 63548 R-BTA-2046097 https://reactome.org/PathwayBrowser/#/R-BTA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 63548 R-CEL-2046097 https://reactome.org/PathwayBrowser/#/R-CEL-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Caenorhabditis elegans 63548 R-CFA-2046095 https://reactome.org/PathwayBrowser/#/R-CFA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Canis familiaris 63548 R-CFA-2046097 https://reactome.org/PathwayBrowser/#/R-CFA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 63548 R-DDI-2046095 https://reactome.org/PathwayBrowser/#/R-DDI-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Dictyostelium discoideum 63548 R-DME-2046095 https://reactome.org/PathwayBrowser/#/R-DME-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Drosophila melanogaster 63548 R-DRE-2046095 https://reactome.org/PathwayBrowser/#/R-DRE-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Danio rerio 63548 R-DRE-2046097 https://reactome.org/PathwayBrowser/#/R-DRE-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 63548 R-GGA-2046095 https://reactome.org/PathwayBrowser/#/R-GGA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Gallus gallus 63548 R-GGA-2046097 https://reactome.org/PathwayBrowser/#/R-GGA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 63548 R-HSA-2046095 https://reactome.org/PathwayBrowser/#/R-HSA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA TAS Homo sapiens 63548 R-HSA-2046097 https://reactome.org/PathwayBrowser/#/R-HSA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 63548 R-MMU-2046095 https://reactome.org/PathwayBrowser/#/R-MMU-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Mus musculus 63548 R-MMU-2046097 https://reactome.org/PathwayBrowser/#/R-MMU-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 63548 R-RNO-2046095 https://reactome.org/PathwayBrowser/#/R-RNO-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Rattus norvegicus 63548 R-RNO-2046097 https://reactome.org/PathwayBrowser/#/R-RNO-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 63548 R-SSC-2046095 https://reactome.org/PathwayBrowser/#/R-SSC-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Sus scrofa 63548 R-SSC-2046097 https://reactome.org/PathwayBrowser/#/R-SSC-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 63548 R-XTR-2046095 https://reactome.org/PathwayBrowser/#/R-XTR-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Xenopus tropicalis 63563 R-BTA-162797 https://reactome.org/PathwayBrowser/#/R-BTA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Bos taurus 63563 R-BTA-162798 https://reactome.org/PathwayBrowser/#/R-BTA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Bos taurus 63563 R-BTA-162873 https://reactome.org/PathwayBrowser/#/R-BTA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Bos taurus 63563 R-BTA-2162225 https://reactome.org/PathwayBrowser/#/R-BTA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Bos taurus 63563 R-BTA-2162227 https://reactome.org/PathwayBrowser/#/R-BTA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Bos taurus 63563 R-BTA-9638076 https://reactome.org/PathwayBrowser/#/R-BTA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Bos taurus 63563 R-CEL-162798 https://reactome.org/PathwayBrowser/#/R-CEL-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Caenorhabditis elegans 63563 R-CEL-162873 https://reactome.org/PathwayBrowser/#/R-CEL-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Caenorhabditis elegans 63563 R-CEL-2162225 https://reactome.org/PathwayBrowser/#/R-CEL-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Caenorhabditis elegans 63563 R-CEL-2162227 https://reactome.org/PathwayBrowser/#/R-CEL-2162227 GUSB tetramer hydrolyses (HA)2 IEA Caenorhabditis elegans 63563 R-CEL-9638076 https://reactome.org/PathwayBrowser/#/R-CEL-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Caenorhabditis elegans 63563 R-CFA-162797 https://reactome.org/PathwayBrowser/#/R-CFA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Canis familiaris 63563 R-CFA-162798 https://reactome.org/PathwayBrowser/#/R-CFA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Canis familiaris 63563 R-CFA-162873 https://reactome.org/PathwayBrowser/#/R-CFA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Canis familiaris 63563 R-CFA-2162225 https://reactome.org/PathwayBrowser/#/R-CFA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Canis familiaris 63563 R-CFA-2162227 https://reactome.org/PathwayBrowser/#/R-CFA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Canis familiaris 63563 R-CFA-9638076 https://reactome.org/PathwayBrowser/#/R-CFA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Canis familiaris 63563 R-DDI-162797 https://reactome.org/PathwayBrowser/#/R-DDI-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Dictyostelium discoideum 63563 R-DDI-162798 https://reactome.org/PathwayBrowser/#/R-DDI-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Dictyostelium discoideum 63563 R-DDI-162873 https://reactome.org/PathwayBrowser/#/R-DDI-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Dictyostelium discoideum 63563 R-DDI-2162225 https://reactome.org/PathwayBrowser/#/R-DDI-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Dictyostelium discoideum 63563 R-DDI-9638076 https://reactome.org/PathwayBrowser/#/R-DDI-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Dictyostelium discoideum 63563 R-DME-162797 https://reactome.org/PathwayBrowser/#/R-DME-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Drosophila melanogaster 63563 R-DME-162798 https://reactome.org/PathwayBrowser/#/R-DME-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Drosophila melanogaster 63563 R-DME-162873 https://reactome.org/PathwayBrowser/#/R-DME-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster 63563 R-DME-2162225 https://reactome.org/PathwayBrowser/#/R-DME-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Drosophila melanogaster 63563 R-DME-2162227 https://reactome.org/PathwayBrowser/#/R-DME-2162227 GUSB tetramer hydrolyses (HA)2 IEA Drosophila melanogaster 63563 R-DME-9638076 https://reactome.org/PathwayBrowser/#/R-DME-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Drosophila melanogaster 63563 R-DRE-162798 https://reactome.org/PathwayBrowser/#/R-DRE-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Danio rerio 63563 R-GGA-162797 https://reactome.org/PathwayBrowser/#/R-GGA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Gallus gallus 63563 R-GGA-162798 https://reactome.org/PathwayBrowser/#/R-GGA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Gallus gallus 63563 R-GGA-162873 https://reactome.org/PathwayBrowser/#/R-GGA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Gallus gallus 63563 R-GGA-2162225 https://reactome.org/PathwayBrowser/#/R-GGA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Gallus gallus 63563 R-GGA-2162227 https://reactome.org/PathwayBrowser/#/R-GGA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Gallus gallus 63563 R-GGA-9638076 https://reactome.org/PathwayBrowser/#/R-GGA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Gallus gallus 63563 R-HSA-162797 https://reactome.org/PathwayBrowser/#/R-HSA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI TAS Homo sapiens 63563 R-HSA-162798 https://reactome.org/PathwayBrowser/#/R-HSA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol TAS Homo sapiens 63563 R-HSA-162873 https://reactome.org/PathwayBrowser/#/R-HSA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate TAS Homo sapiens 63563 R-HSA-2162225 https://reactome.org/PathwayBrowser/#/R-HSA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments TAS Homo sapiens 63563 R-HSA-2162227 https://reactome.org/PathwayBrowser/#/R-HSA-2162227 GUSB tetramer hydrolyses (HA)2 TAS Homo sapiens 63563 R-HSA-548890 https://reactome.org/PathwayBrowser/#/R-HSA-548890 Removal of the third glucose by glucosidase II and release from the chaperone TAS Homo sapiens 63563 R-HSA-9035976 https://reactome.org/PathwayBrowser/#/R-HSA-9035976 Defective HEXA does not cleave the terminall GalNAc from small HA fragments TAS Homo sapiens 63563 R-HSA-9035982 https://reactome.org/PathwayBrowser/#/R-HSA-9035982 Defective HEXB does not cleave the terminal GalNAc from HA fragments TAS Homo sapiens 63563 R-HSA-9638076 https://reactome.org/PathwayBrowser/#/R-HSA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments TAS Homo sapiens 63563 R-MMU-162797 https://reactome.org/PathwayBrowser/#/R-MMU-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Mus musculus 63563 R-MMU-162798 https://reactome.org/PathwayBrowser/#/R-MMU-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Mus musculus 63563 R-MMU-162863 https://reactome.org/PathwayBrowser/#/R-MMU-162863 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol TAS Mus musculus 63563 R-MMU-162873 https://reactome.org/PathwayBrowser/#/R-MMU-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Mus musculus 63563 R-MMU-2162225 https://reactome.org/PathwayBrowser/#/R-MMU-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Mus musculus 63563 R-MMU-2162227 https://reactome.org/PathwayBrowser/#/R-MMU-2162227 GUSB tetramer hydrolyses (HA)2 IEA Mus musculus 63563 R-MMU-9638076 https://reactome.org/PathwayBrowser/#/R-MMU-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Mus musculus 63563 R-PFA-162873 https://reactome.org/PathwayBrowser/#/R-PFA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Plasmodium falciparum 63563 R-RNO-162798 https://reactome.org/PathwayBrowser/#/R-RNO-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Rattus norvegicus 63563 R-RNO-162873 https://reactome.org/PathwayBrowser/#/R-RNO-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Rattus norvegicus 63563 R-RNO-2162225 https://reactome.org/PathwayBrowser/#/R-RNO-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Rattus norvegicus 63563 R-RNO-2162227 https://reactome.org/PathwayBrowser/#/R-RNO-2162227 GUSB tetramer hydrolyses (HA)2 IEA Rattus norvegicus 63563 R-RNO-9638076 https://reactome.org/PathwayBrowser/#/R-RNO-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Rattus norvegicus 63563 R-SCE-162797 https://reactome.org/PathwayBrowser/#/R-SCE-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Saccharomyces cerevisiae 63563 R-SCE-162798 https://reactome.org/PathwayBrowser/#/R-SCE-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Saccharomyces cerevisiae 63563 R-SCE-162873 https://reactome.org/PathwayBrowser/#/R-SCE-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Saccharomyces cerevisiae 63563 R-SPO-162797 https://reactome.org/PathwayBrowser/#/R-SPO-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Schizosaccharomyces pombe 63563 R-SPO-162798 https://reactome.org/PathwayBrowser/#/R-SPO-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Schizosaccharomyces pombe 63563 R-SPO-162873 https://reactome.org/PathwayBrowser/#/R-SPO-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Schizosaccharomyces pombe 63563 R-SSC-162797 https://reactome.org/PathwayBrowser/#/R-SSC-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Sus scrofa 63563 R-SSC-162798 https://reactome.org/PathwayBrowser/#/R-SSC-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Sus scrofa 63563 R-SSC-162873 https://reactome.org/PathwayBrowser/#/R-SSC-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Sus scrofa 63563 R-SSC-2162225 https://reactome.org/PathwayBrowser/#/R-SSC-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Sus scrofa 63563 R-SSC-2162227 https://reactome.org/PathwayBrowser/#/R-SSC-2162227 GUSB tetramer hydrolyses (HA)2 IEA Sus scrofa 63563 R-SSC-9638076 https://reactome.org/PathwayBrowser/#/R-SSC-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Sus scrofa 63563 R-XTR-162798 https://reactome.org/PathwayBrowser/#/R-XTR-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol IEA Xenopus tropicalis 63563 R-XTR-162873 https://reactome.org/PathwayBrowser/#/R-XTR-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Xenopus tropicalis 63563 R-XTR-2162227 https://reactome.org/PathwayBrowser/#/R-XTR-2162227 GUSB tetramer hydrolyses (HA)2 IEA Xenopus tropicalis 63563 R-XTR-9638076 https://reactome.org/PathwayBrowser/#/R-XTR-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Xenopus tropicalis 63579 R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Bos taurus 63579 R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Canis familiaris 63579 R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Danio rerio 63579 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Gallus gallus 63579 R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) TAS Homo sapiens 63579 R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Mus musculus 63579 R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Rattus norvegicus 63579 R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Sus scrofa 63590 R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 63590 R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 63590 R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 63590 R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 63590 R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 63590 R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 63590 R-SSC-211904 https://reactome.org/PathwayBrowser/#/R-SSC-211904 CYP4F12 18-hydroxylates ARA IEA Sus scrofa 63590 R-XTR-211904 https://reactome.org/PathwayBrowser/#/R-XTR-211904 CYP4F12 18-hydroxylates ARA IEA Xenopus tropicalis 63617 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 63617 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 63617 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 63617 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 63617 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 63617 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 63617 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 63617 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 63617 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 63617 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 63622 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 63622 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 63622 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 63622 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 63622 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 63622 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 63622 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 63622 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 63622 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 63622 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 63622 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 63622 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 63622 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 63622 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 63622 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 63622 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 63622 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 63622 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 63622 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 63622 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 63622 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 63622 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 63622 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 63622 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 63622 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 63622 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 63622 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 63622 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 63622 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 63622 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 63622 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 63622 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 63622 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 63622 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 63622 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 63622 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 63622 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 63634 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 63634 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 63634 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 63634 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 63634 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 63634 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 63634 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 63634 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 63634 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 63634 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 63634 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 63634 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 63634 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 63634 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 63634 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 63634 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 63634 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 63634 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 63637 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 63645 R-BTA-2090038 https://reactome.org/PathwayBrowser/#/R-BTA-2090038 NAGLU hydrolyses heparan chain(2) IEA Bos taurus 63645 R-BTA-2090085 https://reactome.org/PathwayBrowser/#/R-BTA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Bos taurus 63645 R-CEL-2090038 https://reactome.org/PathwayBrowser/#/R-CEL-2090038 NAGLU hydrolyses heparan chain(2) IEA Caenorhabditis elegans 63645 R-CFA-2090038 https://reactome.org/PathwayBrowser/#/R-CFA-2090038 NAGLU hydrolyses heparan chain(2) IEA Canis familiaris 63645 R-CFA-2090085 https://reactome.org/PathwayBrowser/#/R-CFA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Canis familiaris 63645 R-DDI-2090038 https://reactome.org/PathwayBrowser/#/R-DDI-2090038 NAGLU hydrolyses heparan chain(2) IEA Dictyostelium discoideum 63645 R-DDI-2090085 https://reactome.org/PathwayBrowser/#/R-DDI-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Dictyostelium discoideum 63645 R-DME-2090038 https://reactome.org/PathwayBrowser/#/R-DME-2090038 NAGLU hydrolyses heparan chain(2) IEA Drosophila melanogaster 63645 R-DME-2090085 https://reactome.org/PathwayBrowser/#/R-DME-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Drosophila melanogaster 63645 R-GGA-2090038 https://reactome.org/PathwayBrowser/#/R-GGA-2090038 NAGLU hydrolyses heparan chain(2) IEA Gallus gallus 63645 R-GGA-2090085 https://reactome.org/PathwayBrowser/#/R-GGA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Gallus gallus 63645 R-HSA-2090038 https://reactome.org/PathwayBrowser/#/R-HSA-2090038 NAGLU hydrolyses heparan chain(2) TAS Homo sapiens 63645 R-HSA-2090085 https://reactome.org/PathwayBrowser/#/R-HSA-2090085 HGSNAT oligomer acetylates Heparan chain(1) TAS Homo sapiens 63645 R-HSA-9036052 https://reactome.org/PathwayBrowser/#/R-HSA-9036052 Defective NAGLU does not hydrolyse heparan chain(2) TAS Homo sapiens 63645 R-MMU-2090038 https://reactome.org/PathwayBrowser/#/R-MMU-2090038 NAGLU hydrolyses heparan chain(2) IEA Mus musculus 63645 R-MMU-2090085 https://reactome.org/PathwayBrowser/#/R-MMU-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Mus musculus 63645 R-RNO-2090038 https://reactome.org/PathwayBrowser/#/R-RNO-2090038 NAGLU hydrolyses heparan chain(2) IEA Rattus norvegicus 63645 R-RNO-2090085 https://reactome.org/PathwayBrowser/#/R-RNO-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Rattus norvegicus 63645 R-SSC-2090038 https://reactome.org/PathwayBrowser/#/R-SSC-2090038 NAGLU hydrolyses heparan chain(2) IEA Sus scrofa 63645 R-SSC-2090085 https://reactome.org/PathwayBrowser/#/R-SSC-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Sus scrofa 63645 R-XTR-2090085 https://reactome.org/PathwayBrowser/#/R-XTR-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Xenopus tropicalis 63666 R-BTA-1667005 https://reactome.org/PathwayBrowser/#/R-BTA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Bos taurus 63666 R-BTA-1678716 https://reactome.org/PathwayBrowser/#/R-BTA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Bos taurus 63666 R-CFA-1667005 https://reactome.org/PathwayBrowser/#/R-CFA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Canis familiaris 63666 R-CFA-1678716 https://reactome.org/PathwayBrowser/#/R-CFA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Canis familiaris 63666 R-DDI-1678716 https://reactome.org/PathwayBrowser/#/R-DDI-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Dictyostelium discoideum 63666 R-DME-1667005 https://reactome.org/PathwayBrowser/#/R-DME-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Drosophila melanogaster 63666 R-DME-1678716 https://reactome.org/PathwayBrowser/#/R-DME-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Drosophila melanogaster 63666 R-DRE-1667005 https://reactome.org/PathwayBrowser/#/R-DRE-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Danio rerio 63666 R-GGA-1667005 https://reactome.org/PathwayBrowser/#/R-GGA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Gallus gallus 63666 R-GGA-1678716 https://reactome.org/PathwayBrowser/#/R-GGA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Gallus gallus 63666 R-HSA-1667005 https://reactome.org/PathwayBrowser/#/R-HSA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) TAS Homo sapiens 63666 R-HSA-1678716 https://reactome.org/PathwayBrowser/#/R-HSA-1678716 IDUA hydrolyses Heparan sulfate chain(1) TAS Homo sapiens 63666 R-HSA-9036037 https://reactome.org/PathwayBrowser/#/R-HSA-9036037 Defective IDUA does not hydrolyse Heparan sulfate chain(1) TAS Homo sapiens 63666 R-MMU-1667005 https://reactome.org/PathwayBrowser/#/R-MMU-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Mus musculus 63666 R-MMU-1678716 https://reactome.org/PathwayBrowser/#/R-MMU-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Mus musculus 63666 R-RNO-1667005 https://reactome.org/PathwayBrowser/#/R-RNO-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Rattus norvegicus 63666 R-RNO-1678716 https://reactome.org/PathwayBrowser/#/R-RNO-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Rattus norvegicus 63666 R-SSC-1667005 https://reactome.org/PathwayBrowser/#/R-SSC-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Sus scrofa 63666 R-SSC-1678716 https://reactome.org/PathwayBrowser/#/R-SSC-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Sus scrofa 63666 R-XTR-1667005 https://reactome.org/PathwayBrowser/#/R-XTR-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Xenopus tropicalis 63666 R-XTR-1678716 https://reactome.org/PathwayBrowser/#/R-XTR-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Xenopus tropicalis 63685 R-HSA-9678128 https://reactome.org/PathwayBrowser/#/R-HSA-9678128 Spike glycoprotein of SARS coronavirus binds ACE2 on host cell TAS Homo sapiens 63685 R-HSA-9684016 https://reactome.org/PathwayBrowser/#/R-HSA-9684016 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 63685 R-HSA-9684017 https://reactome.org/PathwayBrowser/#/R-HSA-9684017 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 63685 R-HSA-9684018 https://reactome.org/PathwayBrowser/#/R-HSA-9684018 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 63685 R-HSA-9684030 https://reactome.org/PathwayBrowser/#/R-HSA-9684030 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 63685 R-HSA-9684032 https://reactome.org/PathwayBrowser/#/R-HSA-9684032 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 63685 R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 63685 R-HSA-9685531 https://reactome.org/PathwayBrowser/#/R-HSA-9685531 SARS virus buds into ERGIC lumen TAS Homo sapiens 63685 R-HSA-9685542 https://reactome.org/PathwayBrowser/#/R-HSA-9685542 Viral release TAS Homo sapiens 63685 R-HSA-9686699 https://reactome.org/PathwayBrowser/#/R-HSA-9686699 Fusion and Release of SARS-CoV-1 Nucleocapsid TAS Homo sapiens 63685 R-HSA-9686709 https://reactome.org/PathwayBrowser/#/R-HSA-9686709 Uncoating of SARS-CoV-1 Genome TAS Homo sapiens 63685 R-HSA-9686710 https://reactome.org/PathwayBrowser/#/R-HSA-9686710 Cleavage of S protein into S1:S2 TAS Homo sapiens 63685 R-HSA-9686711 https://reactome.org/PathwayBrowser/#/R-HSA-9686711 Endocytois of SARS-CoV-1 Virion TAS Homo sapiens 63685 R-HSA-9686731 https://reactome.org/PathwayBrowser/#/R-HSA-9686731 TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 63685 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 63685 R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 63685 R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 63685 R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 63685 R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 63685 R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 63685 R-HSA-9756603 https://reactome.org/PathwayBrowser/#/R-HSA-9756603 SARS-CoV-1 S binds SFTPD 12mer TAS Homo sapiens 63715 R-BTA-2395876 https://reactome.org/PathwayBrowser/#/R-BTA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 63715 R-BTA-2395879 https://reactome.org/PathwayBrowser/#/R-BTA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 63715 R-CEL-2395879 https://reactome.org/PathwayBrowser/#/R-CEL-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Caenorhabditis elegans 63715 R-CFA-2395876 https://reactome.org/PathwayBrowser/#/R-CFA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 63715 R-CFA-2395879 https://reactome.org/PathwayBrowser/#/R-CFA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 63715 R-DME-2395879 https://reactome.org/PathwayBrowser/#/R-DME-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Drosophila melanogaster 63715 R-DRE-2395879 https://reactome.org/PathwayBrowser/#/R-DRE-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Danio rerio 63715 R-GGA-2395876 https://reactome.org/PathwayBrowser/#/R-GGA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Gallus gallus 63715 R-HSA-2395876 https://reactome.org/PathwayBrowser/#/R-HSA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 63715 R-HSA-2395879 https://reactome.org/PathwayBrowser/#/R-HSA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 63715 R-MMU-2395876 https://reactome.org/PathwayBrowser/#/R-MMU-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 63715 R-MMU-2395879 https://reactome.org/PathwayBrowser/#/R-MMU-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 63715 R-RNO-2395876 https://reactome.org/PathwayBrowser/#/R-RNO-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 63715 R-RNO-2395879 https://reactome.org/PathwayBrowser/#/R-RNO-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 63715 R-SSC-2395876 https://reactome.org/PathwayBrowser/#/R-SSC-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 63715 R-SSC-2395879 https://reactome.org/PathwayBrowser/#/R-SSC-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 63715 R-XTR-2395876 https://reactome.org/PathwayBrowser/#/R-XTR-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 63715 R-XTR-2395879 https://reactome.org/PathwayBrowser/#/R-XTR-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 63740 R-BTA-6810472 https://reactome.org/PathwayBrowser/#/R-BTA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Bos taurus 63740 R-CFA-6810472 https://reactome.org/PathwayBrowser/#/R-CFA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Canis familiaris 63740 R-GGA-6810472 https://reactome.org/PathwayBrowser/#/R-GGA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Gallus gallus 63740 R-HSA-6810472 https://reactome.org/PathwayBrowser/#/R-HSA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP TAS Homo sapiens 63740 R-MMU-6810472 https://reactome.org/PathwayBrowser/#/R-MMU-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Mus musculus 63740 R-RNO-6810472 https://reactome.org/PathwayBrowser/#/R-RNO-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Rattus norvegicus 63740 R-SSC-6810472 https://reactome.org/PathwayBrowser/#/R-SSC-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Sus scrofa 63740 R-XTR-6810472 https://reactome.org/PathwayBrowser/#/R-XTR-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Xenopus tropicalis 63795 R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 63795 R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 63795 R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 63795 R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 63795 R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 63795 R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 63795 R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 63795 R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 63795 R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 63795 R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 63795 R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 63795 R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 63795 R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 63795 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 63795 R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 63795 R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 63795 R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 63795 R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 63795 R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 63795 R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 63795 R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 63795 R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 63795 R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 63795 R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 63795 R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 63795 R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 63795 R-SSC-5362525 https://reactome.org/PathwayBrowser/#/R-SSC-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Sus scrofa 63795 R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 63795 R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 63795 R-XTR-5362525 https://reactome.org/PathwayBrowser/#/R-XTR-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Xenopus tropicalis 63797 R-BTA-175983 https://reactome.org/PathwayBrowser/#/R-BTA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Bos taurus 63797 R-CFA-175983 https://reactome.org/PathwayBrowser/#/R-CFA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Canis familiaris 63797 R-DRE-175983 https://reactome.org/PathwayBrowser/#/R-DRE-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Danio rerio 63797 R-GGA-175983 https://reactome.org/PathwayBrowser/#/R-GGA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Gallus gallus 63797 R-HSA-175983 https://reactome.org/PathwayBrowser/#/R-HSA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ TAS Homo sapiens 63797 R-MMU-175983 https://reactome.org/PathwayBrowser/#/R-MMU-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Mus musculus 63797 R-RNO-175983 https://reactome.org/PathwayBrowser/#/R-RNO-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Rattus norvegicus 63797 R-SPO-175983 https://reactome.org/PathwayBrowser/#/R-SPO-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Schizosaccharomyces pombe 63797 R-SSC-175983 https://reactome.org/PathwayBrowser/#/R-SSC-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Sus scrofa 63797 R-XTR-175983 https://reactome.org/PathwayBrowser/#/R-XTR-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ IEA Xenopus tropicalis 63799 R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 63799 R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 63799 R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 63799 R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 63799 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 63799 R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 63799 R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 63799 R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 63799 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 63800 R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 63800 R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 63800 R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 63800 R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 63800 R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 63800 R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 63800 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 63800 R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 63800 R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 63800 R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 63800 R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa 63800 R-XTR-211966 https://reactome.org/PathwayBrowser/#/R-XTR-211966 CYP2D6 4-hydroxylates debrisoquine IEA Xenopus tropicalis 63802 R-BTA-211923 https://reactome.org/PathwayBrowser/#/R-BTA-211923 CYP26C1 4-hydroxylates 9cRA IEA Bos taurus 63802 R-CFA-211923 https://reactome.org/PathwayBrowser/#/R-CFA-211923 CYP26C1 4-hydroxylates 9cRA IEA Canis familiaris 63802 R-DRE-211923 https://reactome.org/PathwayBrowser/#/R-DRE-211923 CYP26C1 4-hydroxylates 9cRA IEA Danio rerio 63802 R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus 63802 R-HSA-211923 https://reactome.org/PathwayBrowser/#/R-HSA-211923 CYP26C1 4-hydroxylates 9cRA TAS Homo sapiens 63802 R-MMU-211923 https://reactome.org/PathwayBrowser/#/R-MMU-211923 CYP26C1 4-hydroxylates 9cRA IEA Mus musculus 63802 R-RNO-211923 https://reactome.org/PathwayBrowser/#/R-RNO-211923 CYP26C1 4-hydroxylates 9cRA IEA Rattus norvegicus 63802 R-SSC-211923 https://reactome.org/PathwayBrowser/#/R-SSC-211923 CYP26C1 4-hydroxylates 9cRA IEA Sus scrofa 63802 R-XTR-211923 https://reactome.org/PathwayBrowser/#/R-XTR-211923 CYP26C1 4-hydroxylates 9cRA IEA Xenopus tropicalis 63803 R-BTA-389889 https://reactome.org/PathwayBrowser/#/R-BTA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Bos taurus 63803 R-BTA-389891 https://reactome.org/PathwayBrowser/#/R-BTA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Bos taurus 63803 R-BTA-389986 https://reactome.org/PathwayBrowser/#/R-BTA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Bos taurus 63803 R-CEL-389889 https://reactome.org/PathwayBrowser/#/R-CEL-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Caenorhabditis elegans 63803 R-CEL-389891 https://reactome.org/PathwayBrowser/#/R-CEL-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Caenorhabditis elegans 63803 R-CEL-389986 https://reactome.org/PathwayBrowser/#/R-CEL-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Caenorhabditis elegans 63803 R-CFA-389889 https://reactome.org/PathwayBrowser/#/R-CFA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Canis familiaris 63803 R-CFA-389891 https://reactome.org/PathwayBrowser/#/R-CFA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Canis familiaris 63803 R-CFA-389986 https://reactome.org/PathwayBrowser/#/R-CFA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Canis familiaris 63803 R-DDI-389889 https://reactome.org/PathwayBrowser/#/R-DDI-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Dictyostelium discoideum 63803 R-DDI-389891 https://reactome.org/PathwayBrowser/#/R-DDI-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Dictyostelium discoideum 63803 R-DDI-389986 https://reactome.org/PathwayBrowser/#/R-DDI-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Dictyostelium discoideum 63803 R-DME-389889 https://reactome.org/PathwayBrowser/#/R-DME-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Drosophila melanogaster 63803 R-DME-389891 https://reactome.org/PathwayBrowser/#/R-DME-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Drosophila melanogaster 63803 R-DME-389986 https://reactome.org/PathwayBrowser/#/R-DME-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Drosophila melanogaster 63803 R-DRE-389891 https://reactome.org/PathwayBrowser/#/R-DRE-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Danio rerio 63803 R-GGA-389889 https://reactome.org/PathwayBrowser/#/R-GGA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Gallus gallus 63803 R-GGA-389891 https://reactome.org/PathwayBrowser/#/R-GGA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Gallus gallus 63803 R-GGA-389986 https://reactome.org/PathwayBrowser/#/R-GGA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Gallus gallus 63803 R-HSA-389889 https://reactome.org/PathwayBrowser/#/R-HSA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA TAS Homo sapiens 63803 R-HSA-389891 https://reactome.org/PathwayBrowser/#/R-HSA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) TAS Homo sapiens 63803 R-HSA-389986 https://reactome.org/PathwayBrowser/#/R-HSA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA TAS Homo sapiens 63803 R-MMU-389889 https://reactome.org/PathwayBrowser/#/R-MMU-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Mus musculus 63803 R-MMU-389891 https://reactome.org/PathwayBrowser/#/R-MMU-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Mus musculus 63803 R-MMU-389986 https://reactome.org/PathwayBrowser/#/R-MMU-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Mus musculus 63803 R-RNO-389889 https://reactome.org/PathwayBrowser/#/R-RNO-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Rattus norvegicus 63803 R-RNO-389891 https://reactome.org/PathwayBrowser/#/R-RNO-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Rattus norvegicus 63803 R-RNO-389986 https://reactome.org/PathwayBrowser/#/R-RNO-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Rattus norvegicus 63803 R-SCE-389891 https://reactome.org/PathwayBrowser/#/R-SCE-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Saccharomyces cerevisiae 63803 R-SSC-389889 https://reactome.org/PathwayBrowser/#/R-SSC-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Sus scrofa 63803 R-SSC-389891 https://reactome.org/PathwayBrowser/#/R-SSC-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Sus scrofa 63803 R-XTR-389889 https://reactome.org/PathwayBrowser/#/R-XTR-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Xenopus tropicalis 63803 R-XTR-389891 https://reactome.org/PathwayBrowser/#/R-XTR-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Xenopus tropicalis 63804 R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 63804 R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 63804 R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 63804 R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 63804 R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 63804 R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 63804 R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 63804 R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 63804 R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 63805 R-BTA-1678708 https://reactome.org/PathwayBrowser/#/R-BTA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Bos taurus 63805 R-BTA-1678716 https://reactome.org/PathwayBrowser/#/R-BTA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Bos taurus 63805 R-CFA-1678708 https://reactome.org/PathwayBrowser/#/R-CFA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Canis familiaris 63805 R-CFA-1678716 https://reactome.org/PathwayBrowser/#/R-CFA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Canis familiaris 63805 R-DDI-1678716 https://reactome.org/PathwayBrowser/#/R-DDI-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Dictyostelium discoideum 63805 R-DME-1678708 https://reactome.org/PathwayBrowser/#/R-DME-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Drosophila melanogaster 63805 R-DME-1678716 https://reactome.org/PathwayBrowser/#/R-DME-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Drosophila melanogaster 63805 R-GGA-1678708 https://reactome.org/PathwayBrowser/#/R-GGA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Gallus gallus 63805 R-GGA-1678716 https://reactome.org/PathwayBrowser/#/R-GGA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Gallus gallus 63805 R-HSA-1678708 https://reactome.org/PathwayBrowser/#/R-HSA-1678708 SGSH hydrolyses Heparan sulfate chain(2) TAS Homo sapiens 63805 R-HSA-1678716 https://reactome.org/PathwayBrowser/#/R-HSA-1678716 IDUA hydrolyses Heparan sulfate chain(1) TAS Homo sapiens 63805 R-HSA-9036050 https://reactome.org/PathwayBrowser/#/R-HSA-9036050 Defective SGSH does not hydrolyse Heparan sulfate chain(2) TAS Homo sapiens 63805 R-MMU-1678708 https://reactome.org/PathwayBrowser/#/R-MMU-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Mus musculus 63805 R-MMU-1678716 https://reactome.org/PathwayBrowser/#/R-MMU-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Mus musculus 63805 R-RNO-1678708 https://reactome.org/PathwayBrowser/#/R-RNO-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Rattus norvegicus 63805 R-RNO-1678716 https://reactome.org/PathwayBrowser/#/R-RNO-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Rattus norvegicus 63805 R-SSC-1678708 https://reactome.org/PathwayBrowser/#/R-SSC-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Sus scrofa 63805 R-SSC-1678716 https://reactome.org/PathwayBrowser/#/R-SSC-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Sus scrofa 63805 R-XTR-1678708 https://reactome.org/PathwayBrowser/#/R-XTR-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Xenopus tropicalis 63805 R-XTR-1678716 https://reactome.org/PathwayBrowser/#/R-XTR-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Xenopus tropicalis 63806 R-BTA-1678660 https://reactome.org/PathwayBrowser/#/R-BTA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Bos taurus 63806 R-BTA-1678708 https://reactome.org/PathwayBrowser/#/R-BTA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Bos taurus 63806 R-CFA-1678660 https://reactome.org/PathwayBrowser/#/R-CFA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Canis familiaris 63806 R-CFA-1678708 https://reactome.org/PathwayBrowser/#/R-CFA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Canis familiaris 63806 R-DDI-1678660 https://reactome.org/PathwayBrowser/#/R-DDI-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Dictyostelium discoideum 63806 R-DME-1678660 https://reactome.org/PathwayBrowser/#/R-DME-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Drosophila melanogaster 63806 R-DME-1678708 https://reactome.org/PathwayBrowser/#/R-DME-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Drosophila melanogaster 63806 R-GGA-1678660 https://reactome.org/PathwayBrowser/#/R-GGA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Gallus gallus 63806 R-GGA-1678708 https://reactome.org/PathwayBrowser/#/R-GGA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Gallus gallus 63806 R-HSA-1678660 https://reactome.org/PathwayBrowser/#/R-HSA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) TAS Homo sapiens 63806 R-HSA-1678708 https://reactome.org/PathwayBrowser/#/R-HSA-1678708 SGSH hydrolyses Heparan sulfate chain(2) TAS Homo sapiens 63806 R-HSA-9036056 https://reactome.org/PathwayBrowser/#/R-HSA-9036056 Defective HGSNAT does not acetylate Heparan sulfate chain(3) TAS Homo sapiens 63806 R-MMU-1678660 https://reactome.org/PathwayBrowser/#/R-MMU-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Mus musculus 63806 R-MMU-1678708 https://reactome.org/PathwayBrowser/#/R-MMU-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Mus musculus 63806 R-RNO-1678660 https://reactome.org/PathwayBrowser/#/R-RNO-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Rattus norvegicus 63806 R-RNO-1678708 https://reactome.org/PathwayBrowser/#/R-RNO-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Rattus norvegicus 63806 R-SSC-1678660 https://reactome.org/PathwayBrowser/#/R-SSC-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Sus scrofa 63806 R-SSC-1678708 https://reactome.org/PathwayBrowser/#/R-SSC-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Sus scrofa 63806 R-XTR-1678660 https://reactome.org/PathwayBrowser/#/R-XTR-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Xenopus tropicalis 63806 R-XTR-1678708 https://reactome.org/PathwayBrowser/#/R-XTR-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Xenopus tropicalis 63807 R-BTA-1678660 https://reactome.org/PathwayBrowser/#/R-BTA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Bos taurus 63807 R-BTA-1678742 https://reactome.org/PathwayBrowser/#/R-BTA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Bos taurus 63807 R-CEL-1678742 https://reactome.org/PathwayBrowser/#/R-CEL-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Caenorhabditis elegans 63807 R-CFA-1678660 https://reactome.org/PathwayBrowser/#/R-CFA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Canis familiaris 63807 R-CFA-1678742 https://reactome.org/PathwayBrowser/#/R-CFA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Canis familiaris 63807 R-DDI-1678660 https://reactome.org/PathwayBrowser/#/R-DDI-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Dictyostelium discoideum 63807 R-DDI-1678742 https://reactome.org/PathwayBrowser/#/R-DDI-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Dictyostelium discoideum 63807 R-DME-1678660 https://reactome.org/PathwayBrowser/#/R-DME-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Drosophila melanogaster 63807 R-DME-1678742 https://reactome.org/PathwayBrowser/#/R-DME-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Drosophila melanogaster 63807 R-GGA-1678660 https://reactome.org/PathwayBrowser/#/R-GGA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Gallus gallus 63807 R-GGA-1678742 https://reactome.org/PathwayBrowser/#/R-GGA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Gallus gallus 63807 R-HSA-1678660 https://reactome.org/PathwayBrowser/#/R-HSA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) TAS Homo sapiens 63807 R-HSA-1678742 https://reactome.org/PathwayBrowser/#/R-HSA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) TAS Homo sapiens 63807 R-HSA-2263496 https://reactome.org/PathwayBrowser/#/R-HSA-2263496 Defective NAGLU does not hydrolyse Heparan sulfate chain(4) TAS Homo sapiens 63807 R-MMU-1678660 https://reactome.org/PathwayBrowser/#/R-MMU-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Mus musculus 63807 R-MMU-1678742 https://reactome.org/PathwayBrowser/#/R-MMU-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Mus musculus 63807 R-RNO-1678660 https://reactome.org/PathwayBrowser/#/R-RNO-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Rattus norvegicus 63807 R-RNO-1678742 https://reactome.org/PathwayBrowser/#/R-RNO-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Rattus norvegicus 63807 R-SSC-1678660 https://reactome.org/PathwayBrowser/#/R-SSC-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Sus scrofa 63807 R-SSC-1678742 https://reactome.org/PathwayBrowser/#/R-SSC-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Sus scrofa 63807 R-XTR-1678660 https://reactome.org/PathwayBrowser/#/R-XTR-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) IEA Xenopus tropicalis 63808 R-BTA-1678650 https://reactome.org/PathwayBrowser/#/R-BTA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Bos taurus 63808 R-BTA-1678742 https://reactome.org/PathwayBrowser/#/R-BTA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Bos taurus 63808 R-CEL-1678742 https://reactome.org/PathwayBrowser/#/R-CEL-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Caenorhabditis elegans 63808 R-CFA-1678650 https://reactome.org/PathwayBrowser/#/R-CFA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Canis familiaris 63808 R-CFA-1678742 https://reactome.org/PathwayBrowser/#/R-CFA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Canis familiaris 63808 R-DDI-1678742 https://reactome.org/PathwayBrowser/#/R-DDI-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Dictyostelium discoideum 63808 R-DME-1678650 https://reactome.org/PathwayBrowser/#/R-DME-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Drosophila melanogaster 63808 R-DME-1678742 https://reactome.org/PathwayBrowser/#/R-DME-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Drosophila melanogaster 63808 R-DRE-1678650 https://reactome.org/PathwayBrowser/#/R-DRE-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Danio rerio 63808 R-GGA-1678650 https://reactome.org/PathwayBrowser/#/R-GGA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Gallus gallus 63808 R-GGA-1678742 https://reactome.org/PathwayBrowser/#/R-GGA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Gallus gallus 63808 R-HSA-1678650 https://reactome.org/PathwayBrowser/#/R-HSA-1678650 IDS hydrolyses Heparan sulfate chain(5) TAS Homo sapiens 63808 R-HSA-1678742 https://reactome.org/PathwayBrowser/#/R-HSA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) TAS Homo sapiens 63808 R-HSA-9036046 https://reactome.org/PathwayBrowser/#/R-HSA-9036046 Defective IDS does not hydrolyse Heparan sulfate chain(5) TAS Homo sapiens 63808 R-MMU-1678650 https://reactome.org/PathwayBrowser/#/R-MMU-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Mus musculus 63808 R-MMU-1678742 https://reactome.org/PathwayBrowser/#/R-MMU-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Mus musculus 63808 R-RNO-1678650 https://reactome.org/PathwayBrowser/#/R-RNO-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Rattus norvegicus 63808 R-RNO-1678742 https://reactome.org/PathwayBrowser/#/R-RNO-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Rattus norvegicus 63808 R-SSC-1678650 https://reactome.org/PathwayBrowser/#/R-SSC-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Sus scrofa 63808 R-SSC-1678742 https://reactome.org/PathwayBrowser/#/R-SSC-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Sus scrofa 63808 R-XTR-1678650 https://reactome.org/PathwayBrowser/#/R-XTR-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Xenopus tropicalis 63809 R-BTA-1678650 https://reactome.org/PathwayBrowser/#/R-BTA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Bos taurus 63809 R-BTA-2090037 https://reactome.org/PathwayBrowser/#/R-BTA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Bos taurus 63809 R-CFA-1678650 https://reactome.org/PathwayBrowser/#/R-CFA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Canis familiaris 63809 R-CFA-2090037 https://reactome.org/PathwayBrowser/#/R-CFA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Canis familiaris 63809 R-DDI-2090037 https://reactome.org/PathwayBrowser/#/R-DDI-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Dictyostelium discoideum 63809 R-DME-1678650 https://reactome.org/PathwayBrowser/#/R-DME-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Drosophila melanogaster 63809 R-DME-2090037 https://reactome.org/PathwayBrowser/#/R-DME-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Drosophila melanogaster 63809 R-DRE-1678650 https://reactome.org/PathwayBrowser/#/R-DRE-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Danio rerio 63809 R-GGA-1678650 https://reactome.org/PathwayBrowser/#/R-GGA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Gallus gallus 63809 R-GGA-2090037 https://reactome.org/PathwayBrowser/#/R-GGA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Gallus gallus 63809 R-HSA-1678650 https://reactome.org/PathwayBrowser/#/R-HSA-1678650 IDS hydrolyses Heparan sulfate chain(5) TAS Homo sapiens 63809 R-HSA-2090037 https://reactome.org/PathwayBrowser/#/R-HSA-2090037 IDUA hydrolyses Heparan sulfate chain(6) TAS Homo sapiens 63809 R-HSA-2206299 https://reactome.org/PathwayBrowser/#/R-HSA-2206299 Defective IDUA does not hydrolyse Heparan sulfate chain(6) TAS Homo sapiens 63809 R-MMU-1678650 https://reactome.org/PathwayBrowser/#/R-MMU-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Mus musculus 63809 R-MMU-2090037 https://reactome.org/PathwayBrowser/#/R-MMU-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Mus musculus 63809 R-RNO-1678650 https://reactome.org/PathwayBrowser/#/R-RNO-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Rattus norvegicus 63809 R-RNO-2090037 https://reactome.org/PathwayBrowser/#/R-RNO-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Rattus norvegicus 63809 R-SSC-1678650 https://reactome.org/PathwayBrowser/#/R-SSC-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Sus scrofa 63809 R-SSC-2090037 https://reactome.org/PathwayBrowser/#/R-SSC-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Sus scrofa 63809 R-XTR-1678650 https://reactome.org/PathwayBrowser/#/R-XTR-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Xenopus tropicalis 63809 R-XTR-2090037 https://reactome.org/PathwayBrowser/#/R-XTR-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Xenopus tropicalis 63810 R-BTA-2090037 https://reactome.org/PathwayBrowser/#/R-BTA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Bos taurus 63810 R-BTA-2090043 https://reactome.org/PathwayBrowser/#/R-BTA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Bos taurus 63810 R-CFA-2090037 https://reactome.org/PathwayBrowser/#/R-CFA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Canis familiaris 63810 R-CFA-2090043 https://reactome.org/PathwayBrowser/#/R-CFA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Canis familiaris 63810 R-DDI-2090037 https://reactome.org/PathwayBrowser/#/R-DDI-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Dictyostelium discoideum 63810 R-DME-2090037 https://reactome.org/PathwayBrowser/#/R-DME-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Drosophila melanogaster 63810 R-DME-2090043 https://reactome.org/PathwayBrowser/#/R-DME-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Drosophila melanogaster 63810 R-GGA-2090037 https://reactome.org/PathwayBrowser/#/R-GGA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Gallus gallus 63810 R-GGA-2090043 https://reactome.org/PathwayBrowser/#/R-GGA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Gallus gallus 63810 R-HSA-2090037 https://reactome.org/PathwayBrowser/#/R-HSA-2090037 IDUA hydrolyses Heparan sulfate chain(6) TAS Homo sapiens 63810 R-HSA-2090043 https://reactome.org/PathwayBrowser/#/R-HSA-2090043 SGSH hydrolyses Heparan sulfate chain(7) TAS Homo sapiens 63810 R-HSA-2263444 https://reactome.org/PathwayBrowser/#/R-HSA-2263444 Defective SGSH does not hydrolyse Heparan sulfate chain(7) TAS Homo sapiens 63810 R-MMU-2090037 https://reactome.org/PathwayBrowser/#/R-MMU-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Mus musculus 63810 R-MMU-2090043 https://reactome.org/PathwayBrowser/#/R-MMU-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Mus musculus 63810 R-RNO-2090037 https://reactome.org/PathwayBrowser/#/R-RNO-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Rattus norvegicus 63810 R-RNO-2090043 https://reactome.org/PathwayBrowser/#/R-RNO-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Rattus norvegicus 63810 R-SSC-2090037 https://reactome.org/PathwayBrowser/#/R-SSC-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Sus scrofa 63810 R-SSC-2090043 https://reactome.org/PathwayBrowser/#/R-SSC-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Sus scrofa 63810 R-XTR-2090037 https://reactome.org/PathwayBrowser/#/R-XTR-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Xenopus tropicalis 63810 R-XTR-2090043 https://reactome.org/PathwayBrowser/#/R-XTR-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Xenopus tropicalis 63811 R-BTA-2090043 https://reactome.org/PathwayBrowser/#/R-BTA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Bos taurus 63811 R-BTA-2090085 https://reactome.org/PathwayBrowser/#/R-BTA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Bos taurus 63811 R-CFA-2090043 https://reactome.org/PathwayBrowser/#/R-CFA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Canis familiaris 63811 R-CFA-2090085 https://reactome.org/PathwayBrowser/#/R-CFA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Canis familiaris 63811 R-DDI-2090085 https://reactome.org/PathwayBrowser/#/R-DDI-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Dictyostelium discoideum 63811 R-DME-2090043 https://reactome.org/PathwayBrowser/#/R-DME-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Drosophila melanogaster 63811 R-DME-2090085 https://reactome.org/PathwayBrowser/#/R-DME-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Drosophila melanogaster 63811 R-GGA-2090043 https://reactome.org/PathwayBrowser/#/R-GGA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Gallus gallus 63811 R-GGA-2090085 https://reactome.org/PathwayBrowser/#/R-GGA-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Gallus gallus 63811 R-HSA-2090043 https://reactome.org/PathwayBrowser/#/R-HSA-2090043 SGSH hydrolyses Heparan sulfate chain(7) TAS Homo sapiens 63811 R-HSA-2090085 https://reactome.org/PathwayBrowser/#/R-HSA-2090085 HGSNAT oligomer acetylates Heparan chain(1) TAS Homo sapiens 63811 R-HSA-2263492 https://reactome.org/PathwayBrowser/#/R-HSA-2263492 Defective HGSNAT does not acetylate Heparan chain(1) TAS Homo sapiens 63811 R-MMU-2090043 https://reactome.org/PathwayBrowser/#/R-MMU-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Mus musculus 63811 R-MMU-2090085 https://reactome.org/PathwayBrowser/#/R-MMU-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Mus musculus 63811 R-RNO-2090043 https://reactome.org/PathwayBrowser/#/R-RNO-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Rattus norvegicus 63811 R-RNO-2090085 https://reactome.org/PathwayBrowser/#/R-RNO-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Rattus norvegicus 63811 R-SSC-2090043 https://reactome.org/PathwayBrowser/#/R-SSC-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Sus scrofa 63811 R-SSC-2090085 https://reactome.org/PathwayBrowser/#/R-SSC-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Sus scrofa 63811 R-XTR-2090043 https://reactome.org/PathwayBrowser/#/R-XTR-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Xenopus tropicalis 63811 R-XTR-2090085 https://reactome.org/PathwayBrowser/#/R-XTR-2090085 HGSNAT oligomer acetylates Heparan chain(1) IEA Xenopus tropicalis 63815 R-BTA-174963 https://reactome.org/PathwayBrowser/#/R-BTA-174963 NAT1 acetylation IEA Bos taurus 63815 R-DRE-174963 https://reactome.org/PathwayBrowser/#/R-DRE-174963 NAT1 acetylation IEA Danio rerio 63815 R-GGA-174963 https://reactome.org/PathwayBrowser/#/R-GGA-174963 NAT1 acetylation IEA Gallus gallus 63815 R-HSA-174963 https://reactome.org/PathwayBrowser/#/R-HSA-174963 NAT1 acetylation TAS Homo sapiens 63815 R-MMU-174963 https://reactome.org/PathwayBrowser/#/R-MMU-174963 NAT1 acetylation IEA Mus musculus 63815 R-RNO-174963 https://reactome.org/PathwayBrowser/#/R-RNO-174963 NAT1 acetylation IEA Rattus norvegicus 63815 R-SSC-174963 https://reactome.org/PathwayBrowser/#/R-SSC-174963 NAT1 acetylation IEA Sus scrofa 63817 R-BTA-174963 https://reactome.org/PathwayBrowser/#/R-BTA-174963 NAT1 acetylation IEA Bos taurus 63817 R-DRE-174963 https://reactome.org/PathwayBrowser/#/R-DRE-174963 NAT1 acetylation IEA Danio rerio 63817 R-GGA-174963 https://reactome.org/PathwayBrowser/#/R-GGA-174963 NAT1 acetylation IEA Gallus gallus 63817 R-HSA-174963 https://reactome.org/PathwayBrowser/#/R-HSA-174963 NAT1 acetylation TAS Homo sapiens 63817 R-MMU-174963 https://reactome.org/PathwayBrowser/#/R-MMU-174963 NAT1 acetylation IEA Mus musculus 63817 R-RNO-174963 https://reactome.org/PathwayBrowser/#/R-RNO-174963 NAT1 acetylation IEA Rattus norvegicus 63817 R-SSC-174963 https://reactome.org/PathwayBrowser/#/R-SSC-174963 NAT1 acetylation IEA Sus scrofa 63818 R-BTA-75883 https://reactome.org/PathwayBrowser/#/R-BTA-75883 DHRS7B reduces GO3P to HXDG3P IEA Bos taurus 63818 R-CEL-75883 https://reactome.org/PathwayBrowser/#/R-CEL-75883 DHRS7B reduces GO3P to HXDG3P IEA Caenorhabditis elegans 63818 R-CFA-75883 https://reactome.org/PathwayBrowser/#/R-CFA-75883 DHRS7B reduces GO3P to HXDG3P IEA Canis familiaris 63818 R-DME-75883 https://reactome.org/PathwayBrowser/#/R-DME-75883 DHRS7B reduces GO3P to HXDG3P IEA Drosophila melanogaster 63818 R-DRE-75883 https://reactome.org/PathwayBrowser/#/R-DRE-75883 DHRS7B reduces GO3P to HXDG3P IEA Danio rerio 63818 R-GGA-75883 https://reactome.org/PathwayBrowser/#/R-GGA-75883 DHRS7B reduces GO3P to HXDG3P IEA Gallus gallus 63818 R-HSA-75883 https://reactome.org/PathwayBrowser/#/R-HSA-75883 DHRS7B reduces GO3P to HXDG3P TAS Homo sapiens 63818 R-MMU-75883 https://reactome.org/PathwayBrowser/#/R-MMU-75883 DHRS7B reduces GO3P to HXDG3P IEA Mus musculus 63818 R-RNO-75883 https://reactome.org/PathwayBrowser/#/R-RNO-75883 DHRS7B reduces GO3P to HXDG3P IEA Rattus norvegicus 63818 R-SSC-75883 https://reactome.org/PathwayBrowser/#/R-SSC-75883 DHRS7B reduces GO3P to HXDG3P IEA Sus scrofa 63818 R-XTR-75883 https://reactome.org/PathwayBrowser/#/R-XTR-75883 DHRS7B reduces GO3P to HXDG3P IEA Xenopus tropicalis 63821 R-BTA-548800 https://reactome.org/PathwayBrowser/#/R-BTA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Bos taurus 63821 R-CEL-548800 https://reactome.org/PathwayBrowser/#/R-CEL-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Caenorhabditis elegans 63821 R-CFA-548800 https://reactome.org/PathwayBrowser/#/R-CFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Canis familiaris 63821 R-DDI-548800 https://reactome.org/PathwayBrowser/#/R-DDI-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Dictyostelium discoideum 63821 R-DME-548800 https://reactome.org/PathwayBrowser/#/R-DME-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Drosophila melanogaster 63821 R-DRE-548800 https://reactome.org/PathwayBrowser/#/R-DRE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Danio rerio 63821 R-GGA-548800 https://reactome.org/PathwayBrowser/#/R-GGA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Gallus gallus 63821 R-HSA-548800 https://reactome.org/PathwayBrowser/#/R-HSA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA TAS Homo sapiens 63821 R-MMU-548800 https://reactome.org/PathwayBrowser/#/R-MMU-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Mus musculus 63821 R-PFA-548800 https://reactome.org/PathwayBrowser/#/R-PFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Plasmodium falciparum 63821 R-RNO-548800 https://reactome.org/PathwayBrowser/#/R-RNO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Rattus norvegicus 63821 R-SCE-548800 https://reactome.org/PathwayBrowser/#/R-SCE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Saccharomyces cerevisiae 63821 R-SPO-548800 https://reactome.org/PathwayBrowser/#/R-SPO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Schizosaccharomyces pombe 63821 R-SSC-548800 https://reactome.org/PathwayBrowser/#/R-SSC-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Sus scrofa 63821 R-XTR-548800 https://reactome.org/PathwayBrowser/#/R-XTR-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Xenopus tropicalis 63824 R-BTA-193713 https://reactome.org/PathwayBrowser/#/R-BTA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Bos taurus 63824 R-BTA-193727 https://reactome.org/PathwayBrowser/#/R-BTA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 63824 R-BTA-193766 https://reactome.org/PathwayBrowser/#/R-BTA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 63824 R-CEL-193727 https://reactome.org/PathwayBrowser/#/R-CEL-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 63824 R-CEL-193766 https://reactome.org/PathwayBrowser/#/R-CEL-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 63824 R-CFA-193713 https://reactome.org/PathwayBrowser/#/R-CFA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Canis familiaris 63824 R-CFA-193727 https://reactome.org/PathwayBrowser/#/R-CFA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 63824 R-CFA-193766 https://reactome.org/PathwayBrowser/#/R-CFA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 63824 R-DME-193727 https://reactome.org/PathwayBrowser/#/R-DME-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 63824 R-DME-193766 https://reactome.org/PathwayBrowser/#/R-DME-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 63824 R-DRE-193766 https://reactome.org/PathwayBrowser/#/R-DRE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 63824 R-GGA-193727 https://reactome.org/PathwayBrowser/#/R-GGA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 63824 R-GGA-193766 https://reactome.org/PathwayBrowser/#/R-GGA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 63824 R-HSA-193713 https://reactome.org/PathwayBrowser/#/R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) TAS Homo sapiens 63824 R-HSA-193722 https://reactome.org/PathwayBrowser/#/R-HSA-193722 TetraHCA is translocated from the mitochondrial matrix to the cytosol TAS Homo sapiens 63824 R-HSA-193727 https://reactome.org/PathwayBrowser/#/R-HSA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 63824 R-HSA-193766 https://reactome.org/PathwayBrowser/#/R-HSA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 63824 R-MMU-193713 https://reactome.org/PathwayBrowser/#/R-MMU-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Mus musculus 63824 R-MMU-193727 https://reactome.org/PathwayBrowser/#/R-MMU-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 63824 R-MMU-193766 https://reactome.org/PathwayBrowser/#/R-MMU-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 63824 R-RNO-193713 https://reactome.org/PathwayBrowser/#/R-RNO-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Rattus norvegicus 63824 R-RNO-193727 https://reactome.org/PathwayBrowser/#/R-RNO-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 63824 R-RNO-193766 https://reactome.org/PathwayBrowser/#/R-RNO-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 63824 R-SCE-193727 https://reactome.org/PathwayBrowser/#/R-SCE-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 63824 R-SCE-193766 https://reactome.org/PathwayBrowser/#/R-SCE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 63824 R-SSC-193713 https://reactome.org/PathwayBrowser/#/R-SSC-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Sus scrofa 63824 R-SSC-193727 https://reactome.org/PathwayBrowser/#/R-SSC-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 63824 R-SSC-193766 https://reactome.org/PathwayBrowser/#/R-SSC-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 63824 R-XTR-193727 https://reactome.org/PathwayBrowser/#/R-XTR-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 63824 R-XTR-193766 https://reactome.org/PathwayBrowser/#/R-XTR-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 63825 R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 63825 R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 63825 R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 63825 R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 63825 R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 63825 R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 63825 R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 63825 R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 63825 R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 63825 R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 63828 R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 63828 R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 63828 R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 63828 R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 63828 R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 63828 R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 63828 R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 63828 R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 63828 R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 63828 R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 63829 R-BTA-193746 https://reactome.org/PathwayBrowser/#/R-BTA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Bos taurus 63829 R-BTA-193758 https://reactome.org/PathwayBrowser/#/R-BTA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Bos taurus 63829 R-CEL-193746 https://reactome.org/PathwayBrowser/#/R-CEL-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Caenorhabditis elegans 63829 R-CEL-193758 https://reactome.org/PathwayBrowser/#/R-CEL-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Caenorhabditis elegans 63829 R-CFA-193746 https://reactome.org/PathwayBrowser/#/R-CFA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Canis familiaris 63829 R-DDI-193746 https://reactome.org/PathwayBrowser/#/R-DDI-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Dictyostelium discoideum 63829 R-DDI-193758 https://reactome.org/PathwayBrowser/#/R-DDI-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Dictyostelium discoideum 63829 R-DME-193746 https://reactome.org/PathwayBrowser/#/R-DME-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Drosophila melanogaster 63829 R-DME-193758 https://reactome.org/PathwayBrowser/#/R-DME-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Drosophila melanogaster 63829 R-GGA-193746 https://reactome.org/PathwayBrowser/#/R-GGA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Gallus gallus 63829 R-HSA-193746 https://reactome.org/PathwayBrowser/#/R-HSA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one TAS Homo sapiens 63829 R-HSA-193758 https://reactome.org/PathwayBrowser/#/R-HSA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol TAS Homo sapiens 63829 R-MMU-193746 https://reactome.org/PathwayBrowser/#/R-MMU-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Mus musculus 63829 R-MMU-193758 https://reactome.org/PathwayBrowser/#/R-MMU-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Mus musculus 63829 R-RNO-193746 https://reactome.org/PathwayBrowser/#/R-RNO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 63829 R-RNO-193758 https://reactome.org/PathwayBrowser/#/R-RNO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Rattus norvegicus 63829 R-SCE-193746 https://reactome.org/PathwayBrowser/#/R-SCE-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Saccharomyces cerevisiae 63829 R-SCE-193758 https://reactome.org/PathwayBrowser/#/R-SCE-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Saccharomyces cerevisiae 63829 R-SPO-193746 https://reactome.org/PathwayBrowser/#/R-SPO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Schizosaccharomyces pombe 63829 R-SPO-193758 https://reactome.org/PathwayBrowser/#/R-SPO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Schizosaccharomyces pombe 63829 R-SSC-193746 https://reactome.org/PathwayBrowser/#/R-SSC-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Sus scrofa 63829 R-SSC-193758 https://reactome.org/PathwayBrowser/#/R-SSC-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Sus scrofa 63829 R-XTR-193746 https://reactome.org/PathwayBrowser/#/R-XTR-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 63829 R-XTR-193758 https://reactome.org/PathwayBrowser/#/R-XTR-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Xenopus tropicalis 63830 R-BTA-193755 https://reactome.org/PathwayBrowser/#/R-BTA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Bos taurus 63830 R-BTA-193781 https://reactome.org/PathwayBrowser/#/R-BTA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Bos taurus 63830 R-CEL-193755 https://reactome.org/PathwayBrowser/#/R-CEL-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Caenorhabditis elegans 63830 R-CEL-193781 https://reactome.org/PathwayBrowser/#/R-CEL-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Caenorhabditis elegans 63830 R-CFA-193755 https://reactome.org/PathwayBrowser/#/R-CFA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Canis familiaris 63830 R-DDI-193755 https://reactome.org/PathwayBrowser/#/R-DDI-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Dictyostelium discoideum 63830 R-DDI-193781 https://reactome.org/PathwayBrowser/#/R-DDI-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Dictyostelium discoideum 63830 R-DME-193755 https://reactome.org/PathwayBrowser/#/R-DME-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Drosophila melanogaster 63830 R-DME-193781 https://reactome.org/PathwayBrowser/#/R-DME-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Drosophila melanogaster 63830 R-GGA-193755 https://reactome.org/PathwayBrowser/#/R-GGA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Gallus gallus 63830 R-HSA-193755 https://reactome.org/PathwayBrowser/#/R-HSA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one TAS Homo sapiens 63830 R-HSA-193781 https://reactome.org/PathwayBrowser/#/R-HSA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol TAS Homo sapiens 63830 R-MMU-193755 https://reactome.org/PathwayBrowser/#/R-MMU-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Mus musculus 63830 R-MMU-193781 https://reactome.org/PathwayBrowser/#/R-MMU-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Mus musculus 63830 R-RNO-193755 https://reactome.org/PathwayBrowser/#/R-RNO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Rattus norvegicus 63830 R-RNO-193781 https://reactome.org/PathwayBrowser/#/R-RNO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Rattus norvegicus 63830 R-SCE-193755 https://reactome.org/PathwayBrowser/#/R-SCE-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Saccharomyces cerevisiae 63830 R-SCE-193781 https://reactome.org/PathwayBrowser/#/R-SCE-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Saccharomyces cerevisiae 63830 R-SPO-193755 https://reactome.org/PathwayBrowser/#/R-SPO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Schizosaccharomyces pombe 63830 R-SPO-193781 https://reactome.org/PathwayBrowser/#/R-SPO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Schizosaccharomyces pombe 63830 R-SSC-193755 https://reactome.org/PathwayBrowser/#/R-SSC-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Sus scrofa 63830 R-SSC-193781 https://reactome.org/PathwayBrowser/#/R-SSC-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Sus scrofa 63830 R-XTR-193755 https://reactome.org/PathwayBrowser/#/R-XTR-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Xenopus tropicalis 63830 R-XTR-193781 https://reactome.org/PathwayBrowser/#/R-XTR-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Xenopus tropicalis 63831 R-BTA-193758 https://reactome.org/PathwayBrowser/#/R-BTA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Bos taurus 63831 R-BTA-193792 https://reactome.org/PathwayBrowser/#/R-BTA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Bos taurus 63831 R-CEL-193758 https://reactome.org/PathwayBrowser/#/R-CEL-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Caenorhabditis elegans 63831 R-CFA-193792 https://reactome.org/PathwayBrowser/#/R-CFA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Canis familiaris 63831 R-DDI-193758 https://reactome.org/PathwayBrowser/#/R-DDI-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Dictyostelium discoideum 63831 R-DME-193758 https://reactome.org/PathwayBrowser/#/R-DME-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Drosophila melanogaster 63831 R-HSA-193715 https://reactome.org/PathwayBrowser/#/R-HSA-193715 5beta-cholestan-3alpha,7alpha,24(S)-triol is translocated from the cytosol to the mitochondrial matrix TAS Homo sapiens 63831 R-HSA-193758 https://reactome.org/PathwayBrowser/#/R-HSA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol TAS Homo sapiens 63831 R-HSA-193792 https://reactome.org/PathwayBrowser/#/R-HSA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 63831 R-HSA-9035960 https://reactome.org/PathwayBrowser/#/R-HSA-9035960 Defective CYP27A1 does not 27-hydroxylate 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 63831 R-MMU-193758 https://reactome.org/PathwayBrowser/#/R-MMU-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Mus musculus 63831 R-MMU-193792 https://reactome.org/PathwayBrowser/#/R-MMU-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Mus musculus 63831 R-RNO-193758 https://reactome.org/PathwayBrowser/#/R-RNO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Rattus norvegicus 63831 R-RNO-193792 https://reactome.org/PathwayBrowser/#/R-RNO-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Rattus norvegicus 63831 R-SCE-193758 https://reactome.org/PathwayBrowser/#/R-SCE-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Saccharomyces cerevisiae 63831 R-SPO-193758 https://reactome.org/PathwayBrowser/#/R-SPO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Schizosaccharomyces pombe 63831 R-SSC-193758 https://reactome.org/PathwayBrowser/#/R-SSC-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Sus scrofa 63831 R-SSC-193792 https://reactome.org/PathwayBrowser/#/R-SSC-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Sus scrofa 63831 R-XTR-193758 https://reactome.org/PathwayBrowser/#/R-XTR-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Xenopus tropicalis 63833 R-BTA-193719 https://reactome.org/PathwayBrowser/#/R-BTA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 63833 R-BTA-193792 https://reactome.org/PathwayBrowser/#/R-BTA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Bos taurus 63833 R-CFA-193719 https://reactome.org/PathwayBrowser/#/R-CFA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 63833 R-CFA-193792 https://reactome.org/PathwayBrowser/#/R-CFA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Canis familiaris 63833 R-HSA-193719 https://reactome.org/PathwayBrowser/#/R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 63833 R-HSA-193792 https://reactome.org/PathwayBrowser/#/R-HSA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 63833 R-MMU-193719 https://reactome.org/PathwayBrowser/#/R-MMU-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 63833 R-MMU-193792 https://reactome.org/PathwayBrowser/#/R-MMU-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Mus musculus 63833 R-RNO-193719 https://reactome.org/PathwayBrowser/#/R-RNO-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 63833 R-RNO-193792 https://reactome.org/PathwayBrowser/#/R-RNO-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Rattus norvegicus 63833 R-SSC-193719 https://reactome.org/PathwayBrowser/#/R-SSC-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 63833 R-SSC-193792 https://reactome.org/PathwayBrowser/#/R-SSC-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Sus scrofa 63834 R-BTA-193781 https://reactome.org/PathwayBrowser/#/R-BTA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Bos taurus 63834 R-BTA-193787 https://reactome.org/PathwayBrowser/#/R-BTA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Bos taurus 63834 R-CEL-193781 https://reactome.org/PathwayBrowser/#/R-CEL-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Caenorhabditis elegans 63834 R-CFA-193787 https://reactome.org/PathwayBrowser/#/R-CFA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Canis familiaris 63834 R-DDI-193781 https://reactome.org/PathwayBrowser/#/R-DDI-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Dictyostelium discoideum 63834 R-DME-193781 https://reactome.org/PathwayBrowser/#/R-DME-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Drosophila melanogaster 63834 R-HSA-193774 https://reactome.org/PathwayBrowser/#/R-HSA-193774 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is translocated from the cytosol to the mitochondrial matrix TAS Homo sapiens 63834 R-HSA-193781 https://reactome.org/PathwayBrowser/#/R-HSA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol TAS Homo sapiens 63834 R-HSA-193787 https://reactome.org/PathwayBrowser/#/R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol TAS Homo sapiens 63834 R-MMU-193781 https://reactome.org/PathwayBrowser/#/R-MMU-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Mus musculus 63834 R-MMU-193787 https://reactome.org/PathwayBrowser/#/R-MMU-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Mus musculus 63834 R-RNO-193781 https://reactome.org/PathwayBrowser/#/R-RNO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Rattus norvegicus 63834 R-RNO-193787 https://reactome.org/PathwayBrowser/#/R-RNO-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Rattus norvegicus 63834 R-SCE-193781 https://reactome.org/PathwayBrowser/#/R-SCE-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Saccharomyces cerevisiae 63834 R-SPO-193781 https://reactome.org/PathwayBrowser/#/R-SPO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Schizosaccharomyces pombe 63834 R-SSC-193781 https://reactome.org/PathwayBrowser/#/R-SSC-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Sus scrofa 63834 R-SSC-193787 https://reactome.org/PathwayBrowser/#/R-SSC-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Sus scrofa 63834 R-XTR-193781 https://reactome.org/PathwayBrowser/#/R-XTR-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Xenopus tropicalis 63835 R-BTA-193780 https://reactome.org/PathwayBrowser/#/R-BTA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Bos taurus 63835 R-BTA-193787 https://reactome.org/PathwayBrowser/#/R-BTA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Bos taurus 63835 R-CFA-193780 https://reactome.org/PathwayBrowser/#/R-CFA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Canis familiaris 63835 R-CFA-193787 https://reactome.org/PathwayBrowser/#/R-CFA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Canis familiaris 63835 R-HSA-193780 https://reactome.org/PathwayBrowser/#/R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al TAS Homo sapiens 63835 R-HSA-193787 https://reactome.org/PathwayBrowser/#/R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol TAS Homo sapiens 63835 R-MMU-193780 https://reactome.org/PathwayBrowser/#/R-MMU-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Mus musculus 63835 R-MMU-193787 https://reactome.org/PathwayBrowser/#/R-MMU-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Mus musculus 63835 R-RNO-193780 https://reactome.org/PathwayBrowser/#/R-RNO-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 63835 R-RNO-193787 https://reactome.org/PathwayBrowser/#/R-RNO-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Rattus norvegicus 63835 R-SSC-193780 https://reactome.org/PathwayBrowser/#/R-SSC-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Sus scrofa 63835 R-SSC-193787 https://reactome.org/PathwayBrowser/#/R-SSC-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Sus scrofa 63836 R-BTA-879562 https://reactome.org/PathwayBrowser/#/R-BTA-879562 SLCO2B1 has a narrow substrate specificity IEA Bos taurus 63836 R-CEL-879562 https://reactome.org/PathwayBrowser/#/R-CEL-879562 SLCO2B1 has a narrow substrate specificity IEA Caenorhabditis elegans 63836 R-CFA-879562 https://reactome.org/PathwayBrowser/#/R-CFA-879562 SLCO2B1 has a narrow substrate specificity IEA Canis familiaris 63836 R-DME-879562 https://reactome.org/PathwayBrowser/#/R-DME-879562 SLCO2B1 has a narrow substrate specificity IEA Drosophila melanogaster 63836 R-DRE-879562 https://reactome.org/PathwayBrowser/#/R-DRE-879562 SLCO2B1 has a narrow substrate specificity IEA Danio rerio 63836 R-GGA-879562 https://reactome.org/PathwayBrowser/#/R-GGA-879562 SLCO2B1 has a narrow substrate specificity IEA Gallus gallus 63836 R-HSA-879562 https://reactome.org/PathwayBrowser/#/R-HSA-879562 SLCO2B1 has a narrow substrate specificity TAS Homo sapiens 63836 R-MMU-879562 https://reactome.org/PathwayBrowser/#/R-MMU-879562 SLCO2B1 has a narrow substrate specificity IEA Mus musculus 63836 R-RNO-879562 https://reactome.org/PathwayBrowser/#/R-RNO-879562 SLCO2B1 has a narrow substrate specificity IEA Rattus norvegicus 63836 R-SSC-879562 https://reactome.org/PathwayBrowser/#/R-SSC-879562 SLCO2B1 has a narrow substrate specificity IEA Sus scrofa 63836 R-XTR-879562 https://reactome.org/PathwayBrowser/#/R-XTR-879562 SLCO2B1 has a narrow substrate specificity IEA Xenopus tropicalis 63837 R-BTA-193052 https://reactome.org/PathwayBrowser/#/R-BTA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Bos taurus 63837 R-BTA-196350 https://reactome.org/PathwayBrowser/#/R-BTA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Bos taurus 63837 R-CFA-193052 https://reactome.org/PathwayBrowser/#/R-CFA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Canis familiaris 63837 R-CFA-196350 https://reactome.org/PathwayBrowser/#/R-CFA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Canis familiaris 63837 R-DRE-193052 https://reactome.org/PathwayBrowser/#/R-DRE-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Danio rerio 63837 R-DRE-196350 https://reactome.org/PathwayBrowser/#/R-DRE-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Danio rerio 63837 R-GGA-193052 https://reactome.org/PathwayBrowser/#/R-GGA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Gallus gallus 63837 R-GGA-196350 https://reactome.org/PathwayBrowser/#/R-GGA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Gallus gallus 63837 R-HSA-193052 https://reactome.org/PathwayBrowser/#/R-HSA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone TAS Homo sapiens 63837 R-HSA-196350 https://reactome.org/PathwayBrowser/#/R-HSA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione TAS Homo sapiens 63837 R-MMU-193052 https://reactome.org/PathwayBrowser/#/R-MMU-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Mus musculus 63837 R-MMU-196350 https://reactome.org/PathwayBrowser/#/R-MMU-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Mus musculus 63837 R-RNO-193052 https://reactome.org/PathwayBrowser/#/R-RNO-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Rattus norvegicus 63837 R-RNO-196350 https://reactome.org/PathwayBrowser/#/R-RNO-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Rattus norvegicus 63837 R-SSC-193052 https://reactome.org/PathwayBrowser/#/R-SSC-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Sus scrofa 63837 R-SSC-196350 https://reactome.org/PathwayBrowser/#/R-SSC-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Sus scrofa 63838 R-BTA-193746 https://reactome.org/PathwayBrowser/#/R-BTA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Bos taurus 63838 R-BTA-193789 https://reactome.org/PathwayBrowser/#/R-BTA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Bos taurus 63838 R-CEL-193746 https://reactome.org/PathwayBrowser/#/R-CEL-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Caenorhabditis elegans 63838 R-CFA-193709 https://reactome.org/PathwayBrowser/#/R-CFA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Canis familiaris 63838 R-CFA-193746 https://reactome.org/PathwayBrowser/#/R-CFA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Canis familiaris 63838 R-CFA-193789 https://reactome.org/PathwayBrowser/#/R-CFA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Canis familiaris 63838 R-DDI-193746 https://reactome.org/PathwayBrowser/#/R-DDI-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Dictyostelium discoideum 63838 R-DME-193746 https://reactome.org/PathwayBrowser/#/R-DME-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Drosophila melanogaster 63838 R-DRE-193709 https://reactome.org/PathwayBrowser/#/R-DRE-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Danio rerio 63838 R-DRE-193789 https://reactome.org/PathwayBrowser/#/R-DRE-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Danio rerio 63838 R-GGA-193746 https://reactome.org/PathwayBrowser/#/R-GGA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Gallus gallus 63838 R-HSA-193709 https://reactome.org/PathwayBrowser/#/R-HSA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL TAS Homo sapiens 63838 R-HSA-193746 https://reactome.org/PathwayBrowser/#/R-HSA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one TAS Homo sapiens 63838 R-HSA-193789 https://reactome.org/PathwayBrowser/#/R-HSA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one TAS Homo sapiens 63838 R-MMU-193709 https://reactome.org/PathwayBrowser/#/R-MMU-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Mus musculus 63838 R-MMU-193746 https://reactome.org/PathwayBrowser/#/R-MMU-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Mus musculus 63838 R-MMU-193789 https://reactome.org/PathwayBrowser/#/R-MMU-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Mus musculus 63838 R-RNO-193709 https://reactome.org/PathwayBrowser/#/R-RNO-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Rattus norvegicus 63838 R-RNO-193746 https://reactome.org/PathwayBrowser/#/R-RNO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 63838 R-RNO-193789 https://reactome.org/PathwayBrowser/#/R-RNO-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 63838 R-SCE-193746 https://reactome.org/PathwayBrowser/#/R-SCE-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Saccharomyces cerevisiae 63838 R-SPO-193746 https://reactome.org/PathwayBrowser/#/R-SPO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Schizosaccharomyces pombe 63838 R-SSC-193709 https://reactome.org/PathwayBrowser/#/R-SSC-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Sus scrofa 63838 R-SSC-193746 https://reactome.org/PathwayBrowser/#/R-SSC-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Sus scrofa 63838 R-SSC-193789 https://reactome.org/PathwayBrowser/#/R-SSC-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Sus scrofa 63838 R-XTR-193709 https://reactome.org/PathwayBrowser/#/R-XTR-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Xenopus tropicalis 63838 R-XTR-193746 https://reactome.org/PathwayBrowser/#/R-XTR-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 63838 R-XTR-193789 https://reactome.org/PathwayBrowser/#/R-XTR-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 63839 R-BTA-193755 https://reactome.org/PathwayBrowser/#/R-BTA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Bos taurus 63839 R-CEL-193755 https://reactome.org/PathwayBrowser/#/R-CEL-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Caenorhabditis elegans 63839 R-CFA-193709 https://reactome.org/PathwayBrowser/#/R-CFA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Canis familiaris 63839 R-CFA-193755 https://reactome.org/PathwayBrowser/#/R-CFA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Canis familiaris 63839 R-DDI-193755 https://reactome.org/PathwayBrowser/#/R-DDI-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Dictyostelium discoideum 63839 R-DME-193755 https://reactome.org/PathwayBrowser/#/R-DME-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Drosophila melanogaster 63839 R-DRE-193709 https://reactome.org/PathwayBrowser/#/R-DRE-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Danio rerio 63839 R-GGA-193755 https://reactome.org/PathwayBrowser/#/R-GGA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Gallus gallus 63839 R-HSA-193709 https://reactome.org/PathwayBrowser/#/R-HSA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL TAS Homo sapiens 63839 R-HSA-193755 https://reactome.org/PathwayBrowser/#/R-HSA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one TAS Homo sapiens 63839 R-MMU-193709 https://reactome.org/PathwayBrowser/#/R-MMU-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Mus musculus 63839 R-MMU-193755 https://reactome.org/PathwayBrowser/#/R-MMU-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Mus musculus 63839 R-RNO-193709 https://reactome.org/PathwayBrowser/#/R-RNO-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Rattus norvegicus 63839 R-RNO-193755 https://reactome.org/PathwayBrowser/#/R-RNO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Rattus norvegicus 63839 R-SCE-193755 https://reactome.org/PathwayBrowser/#/R-SCE-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Saccharomyces cerevisiae 63839 R-SPO-193755 https://reactome.org/PathwayBrowser/#/R-SPO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Schizosaccharomyces pombe 63839 R-SSC-193709 https://reactome.org/PathwayBrowser/#/R-SSC-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Sus scrofa 63839 R-SSC-193755 https://reactome.org/PathwayBrowser/#/R-SSC-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Sus scrofa 63839 R-XTR-193709 https://reactome.org/PathwayBrowser/#/R-XTR-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Xenopus tropicalis 63839 R-XTR-193755 https://reactome.org/PathwayBrowser/#/R-XTR-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Xenopus tropicalis 63840 R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 63840 R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 63840 R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 63840 R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 63840 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 63840 R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 63840 R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 63840 R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 63840 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 63841 R-BTA-194669 https://reactome.org/PathwayBrowser/#/R-BTA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 63841 R-BTA-194689 https://reactome.org/PathwayBrowser/#/R-BTA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Bos taurus 63841 R-CFA-194669 https://reactome.org/PathwayBrowser/#/R-CFA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 63841 R-CFA-194689 https://reactome.org/PathwayBrowser/#/R-CFA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 63841 R-DDI-194669 https://reactome.org/PathwayBrowser/#/R-DDI-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 63841 R-DRE-194669 https://reactome.org/PathwayBrowser/#/R-DRE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 63841 R-DRE-194689 https://reactome.org/PathwayBrowser/#/R-DRE-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Danio rerio 63841 R-GGA-194669 https://reactome.org/PathwayBrowser/#/R-GGA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 63841 R-GGA-194689 https://reactome.org/PathwayBrowser/#/R-GGA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 63841 R-HSA-194669 https://reactome.org/PathwayBrowser/#/R-HSA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 63841 R-HSA-194689 https://reactome.org/PathwayBrowser/#/R-HSA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 63841 R-MMU-194669 https://reactome.org/PathwayBrowser/#/R-MMU-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 63841 R-MMU-194689 https://reactome.org/PathwayBrowser/#/R-MMU-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Mus musculus 63841 R-RNO-194669 https://reactome.org/PathwayBrowser/#/R-RNO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 63841 R-RNO-194689 https://reactome.org/PathwayBrowser/#/R-RNO-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 63841 R-SCE-194669 https://reactome.org/PathwayBrowser/#/R-SCE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 63841 R-SPO-194669 https://reactome.org/PathwayBrowser/#/R-SPO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 63841 R-SSC-194669 https://reactome.org/PathwayBrowser/#/R-SSC-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 63841 R-SSC-194689 https://reactome.org/PathwayBrowser/#/R-SSC-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 63841 R-XTR-194669 https://reactome.org/PathwayBrowser/#/R-XTR-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 63842 R-BTA-194641 https://reactome.org/PathwayBrowser/#/R-BTA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 63842 R-BTA-194642 https://reactome.org/PathwayBrowser/#/R-BTA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Bos taurus 63842 R-CEL-194642 https://reactome.org/PathwayBrowser/#/R-CEL-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Caenorhabditis elegans 63842 R-CFA-194641 https://reactome.org/PathwayBrowser/#/R-CFA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 63842 R-CFA-194642 https://reactome.org/PathwayBrowser/#/R-CFA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Canis familiaris 63842 R-DDI-194641 https://reactome.org/PathwayBrowser/#/R-DDI-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 63842 R-DDI-194642 https://reactome.org/PathwayBrowser/#/R-DDI-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Dictyostelium discoideum 63842 R-DRE-194641 https://reactome.org/PathwayBrowser/#/R-DRE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 63842 R-DRE-194642 https://reactome.org/PathwayBrowser/#/R-DRE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Danio rerio 63842 R-GGA-194641 https://reactome.org/PathwayBrowser/#/R-GGA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 63842 R-GGA-194642 https://reactome.org/PathwayBrowser/#/R-GGA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Gallus gallus 63842 R-HSA-194641 https://reactome.org/PathwayBrowser/#/R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 63842 R-HSA-194642 https://reactome.org/PathwayBrowser/#/R-HSA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one TAS Homo sapiens 63842 R-MMU-194641 https://reactome.org/PathwayBrowser/#/R-MMU-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 63842 R-MMU-194642 https://reactome.org/PathwayBrowser/#/R-MMU-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Mus musculus 63842 R-RNO-194641 https://reactome.org/PathwayBrowser/#/R-RNO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 63842 R-RNO-194642 https://reactome.org/PathwayBrowser/#/R-RNO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Rattus norvegicus 63842 R-SCE-194641 https://reactome.org/PathwayBrowser/#/R-SCE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 63842 R-SCE-194642 https://reactome.org/PathwayBrowser/#/R-SCE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Saccharomyces cerevisiae 63842 R-SPO-194641 https://reactome.org/PathwayBrowser/#/R-SPO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 63842 R-SPO-194642 https://reactome.org/PathwayBrowser/#/R-SPO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Schizosaccharomyces pombe 63842 R-SSC-194641 https://reactome.org/PathwayBrowser/#/R-SSC-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 63842 R-SSC-194642 https://reactome.org/PathwayBrowser/#/R-SSC-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Sus scrofa 63842 R-XTR-194641 https://reactome.org/PathwayBrowser/#/R-XTR-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 63843 R-BTA-193961 https://reactome.org/PathwayBrowser/#/R-BTA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Bos taurus 63843 R-BTA-196372 https://reactome.org/PathwayBrowser/#/R-BTA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Bos taurus 63843 R-CFA-193961 https://reactome.org/PathwayBrowser/#/R-CFA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Canis familiaris 63843 R-CFA-196372 https://reactome.org/PathwayBrowser/#/R-CFA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Canis familiaris 63843 R-DRE-193961 https://reactome.org/PathwayBrowser/#/R-DRE-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Danio rerio 63843 R-DRE-196372 https://reactome.org/PathwayBrowser/#/R-DRE-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Danio rerio 63843 R-GGA-193961 https://reactome.org/PathwayBrowser/#/R-GGA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Gallus gallus 63843 R-GGA-196372 https://reactome.org/PathwayBrowser/#/R-GGA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Gallus gallus 63843 R-HSA-193961 https://reactome.org/PathwayBrowser/#/R-HSA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone TAS Homo sapiens 63843 R-HSA-196372 https://reactome.org/PathwayBrowser/#/R-HSA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol TAS Homo sapiens 63843 R-MMU-193961 https://reactome.org/PathwayBrowser/#/R-MMU-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Mus musculus 63843 R-MMU-196372 https://reactome.org/PathwayBrowser/#/R-MMU-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Mus musculus 63843 R-RNO-193961 https://reactome.org/PathwayBrowser/#/R-RNO-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Rattus norvegicus 63843 R-RNO-196372 https://reactome.org/PathwayBrowser/#/R-RNO-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Rattus norvegicus 63843 R-SSC-193961 https://reactome.org/PathwayBrowser/#/R-SSC-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Sus scrofa 63843 R-SSC-196372 https://reactome.org/PathwayBrowser/#/R-SSC-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Sus scrofa 63844 R-BTA-194669 https://reactome.org/PathwayBrowser/#/R-BTA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 63844 R-BTA-194718 https://reactome.org/PathwayBrowser/#/R-BTA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Bos taurus 63844 R-CEL-194718 https://reactome.org/PathwayBrowser/#/R-CEL-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Caenorhabditis elegans 63844 R-CFA-194669 https://reactome.org/PathwayBrowser/#/R-CFA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 63844 R-CFA-194718 https://reactome.org/PathwayBrowser/#/R-CFA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Canis familiaris 63844 R-DDI-194669 https://reactome.org/PathwayBrowser/#/R-DDI-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 63844 R-DDI-194718 https://reactome.org/PathwayBrowser/#/R-DDI-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Dictyostelium discoideum 63844 R-DRE-194669 https://reactome.org/PathwayBrowser/#/R-DRE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 63844 R-DRE-194718 https://reactome.org/PathwayBrowser/#/R-DRE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Danio rerio 63844 R-GGA-194669 https://reactome.org/PathwayBrowser/#/R-GGA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 63844 R-GGA-194718 https://reactome.org/PathwayBrowser/#/R-GGA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Gallus gallus 63844 R-HSA-194669 https://reactome.org/PathwayBrowser/#/R-HSA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 63844 R-HSA-194718 https://reactome.org/PathwayBrowser/#/R-HSA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) TAS Homo sapiens 63844 R-MMU-194669 https://reactome.org/PathwayBrowser/#/R-MMU-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 63844 R-MMU-194718 https://reactome.org/PathwayBrowser/#/R-MMU-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Mus musculus 63844 R-RNO-194669 https://reactome.org/PathwayBrowser/#/R-RNO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 63844 R-RNO-194718 https://reactome.org/PathwayBrowser/#/R-RNO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Rattus norvegicus 63844 R-SCE-194669 https://reactome.org/PathwayBrowser/#/R-SCE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 63844 R-SCE-194718 https://reactome.org/PathwayBrowser/#/R-SCE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Saccharomyces cerevisiae 63844 R-SPO-194669 https://reactome.org/PathwayBrowser/#/R-SPO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 63844 R-SPO-194718 https://reactome.org/PathwayBrowser/#/R-SPO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Schizosaccharomyces pombe 63844 R-SSC-194669 https://reactome.org/PathwayBrowser/#/R-SSC-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 63844 R-SSC-194718 https://reactome.org/PathwayBrowser/#/R-SSC-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Sus scrofa 63844 R-XTR-194669 https://reactome.org/PathwayBrowser/#/R-XTR-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 63845 R-BTA-174963 https://reactome.org/PathwayBrowser/#/R-BTA-174963 NAT1 acetylation IEA Bos taurus 63845 R-DRE-174963 https://reactome.org/PathwayBrowser/#/R-DRE-174963 NAT1 acetylation IEA Danio rerio 63845 R-GGA-174963 https://reactome.org/PathwayBrowser/#/R-GGA-174963 NAT1 acetylation IEA Gallus gallus 63845 R-HSA-174963 https://reactome.org/PathwayBrowser/#/R-HSA-174963 NAT1 acetylation TAS Homo sapiens 63845 R-MMU-174963 https://reactome.org/PathwayBrowser/#/R-MMU-174963 NAT1 acetylation IEA Mus musculus 63845 R-RNO-174963 https://reactome.org/PathwayBrowser/#/R-RNO-174963 NAT1 acetylation IEA Rattus norvegicus 63845 R-SSC-174963 https://reactome.org/PathwayBrowser/#/R-SSC-174963 NAT1 acetylation IEA Sus scrofa 63846 R-BTA-1630304 https://reactome.org/PathwayBrowser/#/R-BTA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Bos taurus 63846 R-CFA-1630304 https://reactome.org/PathwayBrowser/#/R-CFA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Canis familiaris 63846 R-GGA-1630304 https://reactome.org/PathwayBrowser/#/R-GGA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Gallus gallus 63846 R-HSA-1630304 https://reactome.org/PathwayBrowser/#/R-HSA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate TAS Homo sapiens 63846 R-HSA-1793217 https://reactome.org/PathwayBrowser/#/R-HSA-1793217 Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase TAS Homo sapiens 63846 R-HSA-2263490 https://reactome.org/PathwayBrowser/#/R-HSA-2263490 Defective GALNS does not hydrolyse sulfate from Gal6S in keratan sulfate TAS Homo sapiens 63846 R-MMU-1630304 https://reactome.org/PathwayBrowser/#/R-MMU-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Mus musculus 63846 R-RNO-1630304 https://reactome.org/PathwayBrowser/#/R-RNO-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Rattus norvegicus 63846 R-SPO-1630304 https://reactome.org/PathwayBrowser/#/R-SPO-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Schizosaccharomyces pombe 63846 R-SSC-1630304 https://reactome.org/PathwayBrowser/#/R-SSC-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Sus scrofa 63846 R-XTR-1630304 https://reactome.org/PathwayBrowser/#/R-XTR-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Xenopus tropicalis 63848 R-BTA-193719 https://reactome.org/PathwayBrowser/#/R-BTA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 63848 R-BTA-193737 https://reactome.org/PathwayBrowser/#/R-BTA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Bos taurus 63848 R-CFA-193719 https://reactome.org/PathwayBrowser/#/R-CFA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 63848 R-CFA-193737 https://reactome.org/PathwayBrowser/#/R-CFA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Canis familiaris 63848 R-HSA-193719 https://reactome.org/PathwayBrowser/#/R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 63848 R-HSA-193737 https://reactome.org/PathwayBrowser/#/R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) TAS Homo sapiens 63848 R-MMU-193719 https://reactome.org/PathwayBrowser/#/R-MMU-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 63848 R-MMU-193737 https://reactome.org/PathwayBrowser/#/R-MMU-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Mus musculus 63848 R-RNO-193719 https://reactome.org/PathwayBrowser/#/R-RNO-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 63848 R-RNO-193737 https://reactome.org/PathwayBrowser/#/R-RNO-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Rattus norvegicus 63848 R-SSC-193719 https://reactome.org/PathwayBrowser/#/R-SSC-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 63848 R-SSC-193737 https://reactome.org/PathwayBrowser/#/R-SSC-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Sus scrofa 63849 R-BTA-193713 https://reactome.org/PathwayBrowser/#/R-BTA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Bos taurus 63849 R-BTA-193780 https://reactome.org/PathwayBrowser/#/R-BTA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Bos taurus 63849 R-CFA-193713 https://reactome.org/PathwayBrowser/#/R-CFA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Canis familiaris 63849 R-CFA-193780 https://reactome.org/PathwayBrowser/#/R-CFA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Canis familiaris 63849 R-HSA-193713 https://reactome.org/PathwayBrowser/#/R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) TAS Homo sapiens 63849 R-HSA-193780 https://reactome.org/PathwayBrowser/#/R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al TAS Homo sapiens 63849 R-MMU-193713 https://reactome.org/PathwayBrowser/#/R-MMU-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Mus musculus 63849 R-MMU-193780 https://reactome.org/PathwayBrowser/#/R-MMU-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Mus musculus 63849 R-RNO-193713 https://reactome.org/PathwayBrowser/#/R-RNO-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Rattus norvegicus 63849 R-RNO-193780 https://reactome.org/PathwayBrowser/#/R-RNO-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 63849 R-SSC-193713 https://reactome.org/PathwayBrowser/#/R-SSC-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Sus scrofa 63849 R-SSC-193780 https://reactome.org/PathwayBrowser/#/R-SSC-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Sus scrofa 63850 R-BTA-1630304 https://reactome.org/PathwayBrowser/#/R-BTA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Bos taurus 63850 R-BTA-1630306 https://reactome.org/PathwayBrowser/#/R-BTA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Bos taurus 63850 R-CEL-1630306 https://reactome.org/PathwayBrowser/#/R-CEL-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Caenorhabditis elegans 63850 R-CFA-1630304 https://reactome.org/PathwayBrowser/#/R-CFA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Canis familiaris 63850 R-CFA-1630306 https://reactome.org/PathwayBrowser/#/R-CFA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Canis familiaris 63850 R-DDI-1630306 https://reactome.org/PathwayBrowser/#/R-DDI-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Dictyostelium discoideum 63850 R-DME-1630306 https://reactome.org/PathwayBrowser/#/R-DME-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Drosophila melanogaster 63850 R-GGA-1630304 https://reactome.org/PathwayBrowser/#/R-GGA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Gallus gallus 63850 R-GGA-1630306 https://reactome.org/PathwayBrowser/#/R-GGA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Gallus gallus 63850 R-HSA-1630304 https://reactome.org/PathwayBrowser/#/R-HSA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate TAS Homo sapiens 63850 R-HSA-1630306 https://reactome.org/PathwayBrowser/#/R-HSA-1630306 GLB1 hydrolyses a glycosaminoglycan TAS Homo sapiens 63850 R-HSA-2265534 https://reactome.org/PathwayBrowser/#/R-HSA-2265534 Defective GLB1 does not hydrolyse a glycosaminoglycan TAS Homo sapiens 63850 R-MMU-1630304 https://reactome.org/PathwayBrowser/#/R-MMU-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Mus musculus 63850 R-MMU-1630306 https://reactome.org/PathwayBrowser/#/R-MMU-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Mus musculus 63850 R-RNO-1630304 https://reactome.org/PathwayBrowser/#/R-RNO-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Rattus norvegicus 63850 R-RNO-1630306 https://reactome.org/PathwayBrowser/#/R-RNO-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Rattus norvegicus 63850 R-SPO-1630304 https://reactome.org/PathwayBrowser/#/R-SPO-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Schizosaccharomyces pombe 63850 R-SSC-1630304 https://reactome.org/PathwayBrowser/#/R-SSC-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Sus scrofa 63850 R-SSC-1630306 https://reactome.org/PathwayBrowser/#/R-SSC-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Sus scrofa 63850 R-XTR-1630304 https://reactome.org/PathwayBrowser/#/R-XTR-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Xenopus tropicalis 63850 R-XTR-1630306 https://reactome.org/PathwayBrowser/#/R-XTR-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Xenopus tropicalis 63851 R-BTA-1630306 https://reactome.org/PathwayBrowser/#/R-BTA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Bos taurus 63851 R-BTA-1638032 https://reactome.org/PathwayBrowser/#/R-BTA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Bos taurus 63851 R-CEL-1630306 https://reactome.org/PathwayBrowser/#/R-CEL-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Caenorhabditis elegans 63851 R-CFA-1630306 https://reactome.org/PathwayBrowser/#/R-CFA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Canis familiaris 63851 R-CFA-1638032 https://reactome.org/PathwayBrowser/#/R-CFA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Canis familiaris 63851 R-DDI-1630306 https://reactome.org/PathwayBrowser/#/R-DDI-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Dictyostelium discoideum 63851 R-DME-1630306 https://reactome.org/PathwayBrowser/#/R-DME-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Drosophila melanogaster 63851 R-DME-1638032 https://reactome.org/PathwayBrowser/#/R-DME-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Drosophila melanogaster 63851 R-DRE-1638032 https://reactome.org/PathwayBrowser/#/R-DRE-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Danio rerio 63851 R-GGA-1630306 https://reactome.org/PathwayBrowser/#/R-GGA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Gallus gallus 63851 R-GGA-1638032 https://reactome.org/PathwayBrowser/#/R-GGA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Gallus gallus 63851 R-HSA-1630306 https://reactome.org/PathwayBrowser/#/R-HSA-1630306 GLB1 hydrolyses a glycosaminoglycan TAS Homo sapiens 63851 R-HSA-1638032 https://reactome.org/PathwayBrowser/#/R-HSA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate TAS Homo sapiens 63851 R-HSA-2263495 https://reactome.org/PathwayBrowser/#/R-HSA-2263495 Defective GNS does not hydrolyse 6-sulfate from GlcNAc6S TAS Homo sapiens 63851 R-MMU-1630306 https://reactome.org/PathwayBrowser/#/R-MMU-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Mus musculus 63851 R-MMU-1638032 https://reactome.org/PathwayBrowser/#/R-MMU-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Mus musculus 63851 R-RNO-1630306 https://reactome.org/PathwayBrowser/#/R-RNO-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Rattus norvegicus 63851 R-RNO-1638032 https://reactome.org/PathwayBrowser/#/R-RNO-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Rattus norvegicus 63851 R-SSC-1630306 https://reactome.org/PathwayBrowser/#/R-SSC-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Sus scrofa 63851 R-SSC-1638032 https://reactome.org/PathwayBrowser/#/R-SSC-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Sus scrofa 63851 R-XTR-1630306 https://reactome.org/PathwayBrowser/#/R-XTR-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Xenopus tropicalis 63851 R-XTR-1638032 https://reactome.org/PathwayBrowser/#/R-XTR-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Xenopus tropicalis 63852 R-BTA-1638032 https://reactome.org/PathwayBrowser/#/R-BTA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Bos taurus 63852 R-BTA-1638053 https://reactome.org/PathwayBrowser/#/R-BTA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Bos taurus 63852 R-BTA-9638078 https://reactome.org/PathwayBrowser/#/R-BTA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Bos taurus 63852 R-CEL-1638053 https://reactome.org/PathwayBrowser/#/R-CEL-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Caenorhabditis elegans 63852 R-CEL-9638078 https://reactome.org/PathwayBrowser/#/R-CEL-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Caenorhabditis elegans 63852 R-CFA-1638032 https://reactome.org/PathwayBrowser/#/R-CFA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Canis familiaris 63852 R-CFA-1638053 https://reactome.org/PathwayBrowser/#/R-CFA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Canis familiaris 63852 R-CFA-9638078 https://reactome.org/PathwayBrowser/#/R-CFA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Canis familiaris 63852 R-DDI-1638053 https://reactome.org/PathwayBrowser/#/R-DDI-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Dictyostelium discoideum 63852 R-DDI-9638078 https://reactome.org/PathwayBrowser/#/R-DDI-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Dictyostelium discoideum 63852 R-DME-1638032 https://reactome.org/PathwayBrowser/#/R-DME-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Drosophila melanogaster 63852 R-DME-1638053 https://reactome.org/PathwayBrowser/#/R-DME-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Drosophila melanogaster 63852 R-DME-9638078 https://reactome.org/PathwayBrowser/#/R-DME-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Drosophila melanogaster 63852 R-DRE-1638032 https://reactome.org/PathwayBrowser/#/R-DRE-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Danio rerio 63852 R-GGA-1638032 https://reactome.org/PathwayBrowser/#/R-GGA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Gallus gallus 63852 R-GGA-1638053 https://reactome.org/PathwayBrowser/#/R-GGA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Gallus gallus 63852 R-GGA-9638078 https://reactome.org/PathwayBrowser/#/R-GGA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Gallus gallus 63852 R-HSA-1638032 https://reactome.org/PathwayBrowser/#/R-HSA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate TAS Homo sapiens 63852 R-HSA-1638053 https://reactome.org/PathwayBrowser/#/R-HSA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate TAS Homo sapiens 63852 R-HSA-9035978 https://reactome.org/PathwayBrowser/#/R-HSA-9035978 Defective HEXA does not cleave the terminal GalNAc from keratan sulfate TAS Homo sapiens 63852 R-HSA-9035983 https://reactome.org/PathwayBrowser/#/R-HSA-9035983 Defective HEXB does not cleave the terminal GalNAc from keratan sulfate TAS Homo sapiens 63852 R-HSA-9638078 https://reactome.org/PathwayBrowser/#/R-HSA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate TAS Homo sapiens 63852 R-MMU-1638032 https://reactome.org/PathwayBrowser/#/R-MMU-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Mus musculus 63852 R-MMU-1638053 https://reactome.org/PathwayBrowser/#/R-MMU-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Mus musculus 63852 R-MMU-9638078 https://reactome.org/PathwayBrowser/#/R-MMU-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Mus musculus 63852 R-RNO-1638032 https://reactome.org/PathwayBrowser/#/R-RNO-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Rattus norvegicus 63852 R-RNO-1638053 https://reactome.org/PathwayBrowser/#/R-RNO-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Rattus norvegicus 63852 R-RNO-9638078 https://reactome.org/PathwayBrowser/#/R-RNO-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Rattus norvegicus 63852 R-SSC-1638032 https://reactome.org/PathwayBrowser/#/R-SSC-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Sus scrofa 63852 R-SSC-1638053 https://reactome.org/PathwayBrowser/#/R-SSC-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Sus scrofa 63852 R-SSC-9638078 https://reactome.org/PathwayBrowser/#/R-SSC-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Sus scrofa 63852 R-XTR-1638032 https://reactome.org/PathwayBrowser/#/R-XTR-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Xenopus tropicalis 63852 R-XTR-9638078 https://reactome.org/PathwayBrowser/#/R-XTR-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Xenopus tropicalis 63853 R-BTA-1638053 https://reactome.org/PathwayBrowser/#/R-BTA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Bos taurus 63853 R-BTA-9638078 https://reactome.org/PathwayBrowser/#/R-BTA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Bos taurus 63853 R-CEL-1638053 https://reactome.org/PathwayBrowser/#/R-CEL-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Caenorhabditis elegans 63853 R-CEL-9638078 https://reactome.org/PathwayBrowser/#/R-CEL-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Caenorhabditis elegans 63853 R-CFA-1638053 https://reactome.org/PathwayBrowser/#/R-CFA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Canis familiaris 63853 R-CFA-9638078 https://reactome.org/PathwayBrowser/#/R-CFA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Canis familiaris 63853 R-DDI-1638053 https://reactome.org/PathwayBrowser/#/R-DDI-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Dictyostelium discoideum 63853 R-DDI-9638078 https://reactome.org/PathwayBrowser/#/R-DDI-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Dictyostelium discoideum 63853 R-DME-1638053 https://reactome.org/PathwayBrowser/#/R-DME-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Drosophila melanogaster 63853 R-DME-9638078 https://reactome.org/PathwayBrowser/#/R-DME-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Drosophila melanogaster 63853 R-GGA-1638053 https://reactome.org/PathwayBrowser/#/R-GGA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Gallus gallus 63853 R-GGA-9638078 https://reactome.org/PathwayBrowser/#/R-GGA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Gallus gallus 63853 R-HSA-1638053 https://reactome.org/PathwayBrowser/#/R-HSA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate TAS Homo sapiens 63853 R-HSA-9638078 https://reactome.org/PathwayBrowser/#/R-HSA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate TAS Homo sapiens 63853 R-MMU-1638053 https://reactome.org/PathwayBrowser/#/R-MMU-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Mus musculus 63853 R-MMU-9638078 https://reactome.org/PathwayBrowser/#/R-MMU-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Mus musculus 63853 R-RNO-1638053 https://reactome.org/PathwayBrowser/#/R-RNO-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Rattus norvegicus 63853 R-RNO-9638078 https://reactome.org/PathwayBrowser/#/R-RNO-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Rattus norvegicus 63853 R-SSC-1638053 https://reactome.org/PathwayBrowser/#/R-SSC-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Sus scrofa 63853 R-SSC-9638078 https://reactome.org/PathwayBrowser/#/R-SSC-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Sus scrofa 63853 R-XTR-9638078 https://reactome.org/PathwayBrowser/#/R-XTR-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Xenopus tropicalis 63856 R-BTA-390281 https://reactome.org/PathwayBrowser/#/R-BTA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Bos taurus 63856 R-CEL-390281 https://reactome.org/PathwayBrowser/#/R-CEL-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Caenorhabditis elegans 63856 R-CFA-390281 https://reactome.org/PathwayBrowser/#/R-CFA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Canis familiaris 63856 R-DME-390281 https://reactome.org/PathwayBrowser/#/R-DME-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Drosophila melanogaster 63856 R-DRE-390281 https://reactome.org/PathwayBrowser/#/R-DRE-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Danio rerio 63856 R-GGA-390281 https://reactome.org/PathwayBrowser/#/R-GGA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Gallus gallus 63856 R-HSA-390276 https://reactome.org/PathwayBrowser/#/R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA TAS Homo sapiens 63856 R-HSA-390281 https://reactome.org/PathwayBrowser/#/R-HSA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH TAS Homo sapiens 63856 R-MMU-390281 https://reactome.org/PathwayBrowser/#/R-MMU-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Mus musculus 63856 R-RNO-390281 https://reactome.org/PathwayBrowser/#/R-RNO-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Rattus norvegicus 63856 R-SSC-390281 https://reactome.org/PathwayBrowser/#/R-SSC-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Sus scrofa 63856 R-XTR-390281 https://reactome.org/PathwayBrowser/#/R-XTR-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Xenopus tropicalis 63859 R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 63859 R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 63859 R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 63859 R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 63859 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 63859 R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 63859 R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 63859 R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 63859 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 63860 R-BTA-174916 https://reactome.org/PathwayBrowser/#/R-BTA-174916 Formation of N-glucuronides IEA Bos taurus 63860 R-DDI-174916 https://reactome.org/PathwayBrowser/#/R-DDI-174916 Formation of N-glucuronides IEA Dictyostelium discoideum 63860 R-GGA-174916 https://reactome.org/PathwayBrowser/#/R-GGA-174916 Formation of N-glucuronides IEA Gallus gallus 63860 R-HSA-174916 https://reactome.org/PathwayBrowser/#/R-HSA-174916 Formation of N-glucuronides TAS Homo sapiens 63860 R-MMU-174916 https://reactome.org/PathwayBrowser/#/R-MMU-174916 Formation of N-glucuronides IEA Mus musculus 63860 R-RNO-174916 https://reactome.org/PathwayBrowser/#/R-RNO-174916 Formation of N-glucuronides IEA Rattus norvegicus 63860 R-SSC-174916 https://reactome.org/PathwayBrowser/#/R-SSC-174916 Formation of N-glucuronides IEA Sus scrofa 63861 R-HSA-175976 https://reactome.org/PathwayBrowser/#/R-HSA-175976 TMT transfers CH3 from AdoMet to BME TAS Homo sapiens 63868 R-BTA-1793186 https://reactome.org/PathwayBrowser/#/R-BTA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Bos taurus 63868 R-CFA-1793186 https://reactome.org/PathwayBrowser/#/R-CFA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Canis familiaris 63868 R-DDI-1793186 https://reactome.org/PathwayBrowser/#/R-DDI-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Dictyostelium discoideum 63868 R-DME-1793186 https://reactome.org/PathwayBrowser/#/R-DME-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Drosophila melanogaster 63868 R-GGA-1793186 https://reactome.org/PathwayBrowser/#/R-GGA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Gallus gallus 63868 R-HSA-1793186 https://reactome.org/PathwayBrowser/#/R-HSA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS TAS Homo sapiens 63868 R-MMU-1793186 https://reactome.org/PathwayBrowser/#/R-MMU-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Mus musculus 63868 R-RNO-1793186 https://reactome.org/PathwayBrowser/#/R-RNO-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Rattus norvegicus 63868 R-SSC-1793186 https://reactome.org/PathwayBrowser/#/R-SSC-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Sus scrofa 63868 R-XTR-1793186 https://reactome.org/PathwayBrowser/#/R-XTR-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Xenopus tropicalis 63873 R-BTA-1793186 https://reactome.org/PathwayBrowser/#/R-BTA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Bos taurus 63873 R-BTA-2105001 https://reactome.org/PathwayBrowser/#/R-BTA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Bos taurus 63873 R-BTA-9638075 https://reactome.org/PathwayBrowser/#/R-BTA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Bos taurus 63873 R-CEL-2105001 https://reactome.org/PathwayBrowser/#/R-CEL-2105001 HEXA cleaves the terminal GalNAc from DS IEA Caenorhabditis elegans 63873 R-CEL-9638075 https://reactome.org/PathwayBrowser/#/R-CEL-9638075 HEXB cleaves the terminal GalNAc from DS IEA Caenorhabditis elegans 63873 R-CFA-1793186 https://reactome.org/PathwayBrowser/#/R-CFA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Canis familiaris 63873 R-CFA-2105001 https://reactome.org/PathwayBrowser/#/R-CFA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Canis familiaris 63873 R-CFA-9638075 https://reactome.org/PathwayBrowser/#/R-CFA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Canis familiaris 63873 R-DDI-1793186 https://reactome.org/PathwayBrowser/#/R-DDI-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Dictyostelium discoideum 63873 R-DDI-2105001 https://reactome.org/PathwayBrowser/#/R-DDI-2105001 HEXA cleaves the terminal GalNAc from DS IEA Dictyostelium discoideum 63873 R-DDI-9638075 https://reactome.org/PathwayBrowser/#/R-DDI-9638075 HEXB cleaves the terminal GalNAc from DS IEA Dictyostelium discoideum 63873 R-DME-1793186 https://reactome.org/PathwayBrowser/#/R-DME-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Drosophila melanogaster 63873 R-DME-2105001 https://reactome.org/PathwayBrowser/#/R-DME-2105001 HEXA cleaves the terminal GalNAc from DS IEA Drosophila melanogaster 63873 R-DME-9638075 https://reactome.org/PathwayBrowser/#/R-DME-9638075 HEXB cleaves the terminal GalNAc from DS IEA Drosophila melanogaster 63873 R-GGA-1793186 https://reactome.org/PathwayBrowser/#/R-GGA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Gallus gallus 63873 R-GGA-2105001 https://reactome.org/PathwayBrowser/#/R-GGA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Gallus gallus 63873 R-GGA-9638075 https://reactome.org/PathwayBrowser/#/R-GGA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Gallus gallus 63873 R-HSA-1793186 https://reactome.org/PathwayBrowser/#/R-HSA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS TAS Homo sapiens 63873 R-HSA-2105001 https://reactome.org/PathwayBrowser/#/R-HSA-2105001 HEXA cleaves the terminal GalNAc from DS TAS Homo sapiens 63873 R-HSA-9036041 https://reactome.org/PathwayBrowser/#/R-HSA-9036041 Defective IDUA does not hydrolyse the unsulfated alpha-L-iduronosidic link in DS TAS Homo sapiens 63873 R-HSA-9638075 https://reactome.org/PathwayBrowser/#/R-HSA-9638075 HEXB cleaves the terminal GalNAc from DS TAS Homo sapiens 63873 R-MMU-1793186 https://reactome.org/PathwayBrowser/#/R-MMU-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Mus musculus 63873 R-MMU-2105001 https://reactome.org/PathwayBrowser/#/R-MMU-2105001 HEXA cleaves the terminal GalNAc from DS IEA Mus musculus 63873 R-MMU-9638075 https://reactome.org/PathwayBrowser/#/R-MMU-9638075 HEXB cleaves the terminal GalNAc from DS IEA Mus musculus 63873 R-RNO-1793186 https://reactome.org/PathwayBrowser/#/R-RNO-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Rattus norvegicus 63873 R-RNO-2105001 https://reactome.org/PathwayBrowser/#/R-RNO-2105001 HEXA cleaves the terminal GalNAc from DS IEA Rattus norvegicus 63873 R-RNO-9638075 https://reactome.org/PathwayBrowser/#/R-RNO-9638075 HEXB cleaves the terminal GalNAc from DS IEA Rattus norvegicus 63873 R-SSC-1793186 https://reactome.org/PathwayBrowser/#/R-SSC-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Sus scrofa 63873 R-SSC-2105001 https://reactome.org/PathwayBrowser/#/R-SSC-2105001 HEXA cleaves the terminal GalNAc from DS IEA Sus scrofa 63873 R-SSC-9638075 https://reactome.org/PathwayBrowser/#/R-SSC-9638075 HEXB cleaves the terminal GalNAc from DS IEA Sus scrofa 63873 R-XTR-1793186 https://reactome.org/PathwayBrowser/#/R-XTR-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Xenopus tropicalis 63873 R-XTR-9638075 https://reactome.org/PathwayBrowser/#/R-XTR-9638075 HEXB cleaves the terminal GalNAc from DS IEA Xenopus tropicalis 63874 R-BTA-390281 https://reactome.org/PathwayBrowser/#/R-BTA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Bos taurus 63874 R-CEL-390281 https://reactome.org/PathwayBrowser/#/R-CEL-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Caenorhabditis elegans 63874 R-CFA-390281 https://reactome.org/PathwayBrowser/#/R-CFA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Canis familiaris 63874 R-DME-390281 https://reactome.org/PathwayBrowser/#/R-DME-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Drosophila melanogaster 63874 R-DRE-390281 https://reactome.org/PathwayBrowser/#/R-DRE-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Danio rerio 63874 R-GGA-390281 https://reactome.org/PathwayBrowser/#/R-GGA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Gallus gallus 63874 R-HSA-390281 https://reactome.org/PathwayBrowser/#/R-HSA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH TAS Homo sapiens 63874 R-MMU-390281 https://reactome.org/PathwayBrowser/#/R-MMU-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Mus musculus 63874 R-RNO-390281 https://reactome.org/PathwayBrowser/#/R-RNO-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Rattus norvegicus 63874 R-SSC-390281 https://reactome.org/PathwayBrowser/#/R-SSC-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Sus scrofa 63874 R-XTR-390281 https://reactome.org/PathwayBrowser/#/R-XTR-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Xenopus tropicalis 63904 R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 63904 R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 63904 R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 63904 R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 63904 R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 63904 R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 63904 R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa 63904 R-XTR-211962 https://reactome.org/PathwayBrowser/#/R-XTR-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Xenopus tropicalis 63905 R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 63905 R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 63905 R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 63905 R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 63905 R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 63905 R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 63905 R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 63905 R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 63905 R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 63905 R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa 63905 R-XTR-212005 https://reactome.org/PathwayBrowser/#/R-XTR-212005 CYP2F1 dehydrogenates 3-methylindole IEA Xenopus tropicalis 63907 R-BTA-200676 https://reactome.org/PathwayBrowser/#/R-BTA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Bos taurus 63907 R-BTA-200681 https://reactome.org/PathwayBrowser/#/R-BTA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Bos taurus 63907 R-BTA-6801342 https://reactome.org/PathwayBrowser/#/R-BTA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Bos taurus 63907 R-CEL-200676 https://reactome.org/PathwayBrowser/#/R-CEL-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Caenorhabditis elegans 63907 R-CEL-200681 https://reactome.org/PathwayBrowser/#/R-CEL-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Caenorhabditis elegans 63907 R-CEL-6801342 https://reactome.org/PathwayBrowser/#/R-CEL-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Caenorhabditis elegans 63907 R-CFA-200676 https://reactome.org/PathwayBrowser/#/R-CFA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Canis familiaris 63907 R-CFA-200681 https://reactome.org/PathwayBrowser/#/R-CFA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Canis familiaris 63907 R-CFA-6801342 https://reactome.org/PathwayBrowser/#/R-CFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Canis familiaris 63907 R-DDI-200676 https://reactome.org/PathwayBrowser/#/R-DDI-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Dictyostelium discoideum 63907 R-DDI-200681 https://reactome.org/PathwayBrowser/#/R-DDI-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Dictyostelium discoideum 63907 R-DME-200676 https://reactome.org/PathwayBrowser/#/R-DME-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Drosophila melanogaster 63907 R-DME-200681 https://reactome.org/PathwayBrowser/#/R-DME-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Drosophila melanogaster 63907 R-DME-6801342 https://reactome.org/PathwayBrowser/#/R-DME-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Drosophila melanogaster 63907 R-DRE-200676 https://reactome.org/PathwayBrowser/#/R-DRE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Danio rerio 63907 R-DRE-200681 https://reactome.org/PathwayBrowser/#/R-DRE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Danio rerio 63907 R-DRE-6801342 https://reactome.org/PathwayBrowser/#/R-DRE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio 63907 R-GGA-200676 https://reactome.org/PathwayBrowser/#/R-GGA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Gallus gallus 63907 R-GGA-200681 https://reactome.org/PathwayBrowser/#/R-GGA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Gallus gallus 63907 R-GGA-6801342 https://reactome.org/PathwayBrowser/#/R-GGA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Gallus gallus 63907 R-HSA-200676 https://reactome.org/PathwayBrowser/#/R-HSA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG TAS Homo sapiens 63907 R-HSA-200681 https://reactome.org/PathwayBrowser/#/R-HSA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG TAS Homo sapiens 63907 R-HSA-6801342 https://reactome.org/PathwayBrowser/#/R-HSA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG TAS Homo sapiens 63907 R-MMU-200676 https://reactome.org/PathwayBrowser/#/R-MMU-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Mus musculus 63907 R-MMU-200681 https://reactome.org/PathwayBrowser/#/R-MMU-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Mus musculus 63907 R-MMU-6801342 https://reactome.org/PathwayBrowser/#/R-MMU-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Mus musculus 63907 R-PFA-6801342 https://reactome.org/PathwayBrowser/#/R-PFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Plasmodium falciparum 63907 R-RNO-200676 https://reactome.org/PathwayBrowser/#/R-RNO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Rattus norvegicus 63907 R-RNO-200681 https://reactome.org/PathwayBrowser/#/R-RNO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Rattus norvegicus 63907 R-RNO-6801342 https://reactome.org/PathwayBrowser/#/R-RNO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Rattus norvegicus 63907 R-SCE-200676 https://reactome.org/PathwayBrowser/#/R-SCE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Saccharomyces cerevisiae 63907 R-SCE-200681 https://reactome.org/PathwayBrowser/#/R-SCE-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Saccharomyces cerevisiae 63907 R-SCE-6801342 https://reactome.org/PathwayBrowser/#/R-SCE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Saccharomyces cerevisiae 63907 R-SPO-200676 https://reactome.org/PathwayBrowser/#/R-SPO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Schizosaccharomyces pombe 63907 R-SPO-200681 https://reactome.org/PathwayBrowser/#/R-SPO-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Schizosaccharomyces pombe 63907 R-SPO-6801342 https://reactome.org/PathwayBrowser/#/R-SPO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Schizosaccharomyces pombe 63907 R-SSC-200676 https://reactome.org/PathwayBrowser/#/R-SSC-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Sus scrofa 63907 R-SSC-200681 https://reactome.org/PathwayBrowser/#/R-SSC-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Sus scrofa 63907 R-SSC-6801342 https://reactome.org/PathwayBrowser/#/R-SSC-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Sus scrofa 63907 R-XTR-200676 https://reactome.org/PathwayBrowser/#/R-XTR-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Xenopus tropicalis 63907 R-XTR-200681 https://reactome.org/PathwayBrowser/#/R-XTR-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Xenopus tropicalis 63907 R-XTR-6801342 https://reactome.org/PathwayBrowser/#/R-XTR-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Xenopus tropicalis 63910 R-BTA-196060 https://reactome.org/PathwayBrowser/#/R-BTA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Bos taurus 63910 R-CEL-196060 https://reactome.org/PathwayBrowser/#/R-CEL-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Caenorhabditis elegans 63910 R-CFA-196060 https://reactome.org/PathwayBrowser/#/R-CFA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Canis familiaris 63910 R-DDI-196060 https://reactome.org/PathwayBrowser/#/R-DDI-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Dictyostelium discoideum 63910 R-DME-196060 https://reactome.org/PathwayBrowser/#/R-DME-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Drosophila melanogaster 63910 R-DRE-196060 https://reactome.org/PathwayBrowser/#/R-DRE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Danio rerio 63910 R-GGA-196060 https://reactome.org/PathwayBrowser/#/R-GGA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Gallus gallus 63910 R-HSA-196060 https://reactome.org/PathwayBrowser/#/R-HSA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol TAS Homo sapiens 63910 R-MMU-196060 https://reactome.org/PathwayBrowser/#/R-MMU-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Mus musculus 63910 R-RNO-196060 https://reactome.org/PathwayBrowser/#/R-RNO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Rattus norvegicus 63910 R-SCE-196060 https://reactome.org/PathwayBrowser/#/R-SCE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Saccharomyces cerevisiae 63910 R-SPO-196060 https://reactome.org/PathwayBrowser/#/R-SPO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Schizosaccharomyces pombe 63910 R-SSC-196060 https://reactome.org/PathwayBrowser/#/R-SSC-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Sus scrofa 63910 R-XTR-196060 https://reactome.org/PathwayBrowser/#/R-XTR-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Xenopus tropicalis 63911 R-BTA-211950 https://reactome.org/PathwayBrowser/#/R-BTA-211950 CYP24A1 24-hydroxylates CTL IEA Bos taurus 63911 R-CFA-211950 https://reactome.org/PathwayBrowser/#/R-CFA-211950 CYP24A1 24-hydroxylates CTL IEA Canis familiaris 63911 R-DRE-211950 https://reactome.org/PathwayBrowser/#/R-DRE-211950 CYP24A1 24-hydroxylates CTL IEA Danio rerio 63911 R-HSA-211950 https://reactome.org/PathwayBrowser/#/R-HSA-211950 CYP24A1 24-hydroxylates CTL TAS Homo sapiens 63911 R-MMU-211950 https://reactome.org/PathwayBrowser/#/R-MMU-211950 CYP24A1 24-hydroxylates CTL IEA Mus musculus 63911 R-RNO-211950 https://reactome.org/PathwayBrowser/#/R-RNO-211950 CYP24A1 24-hydroxylates CTL IEA Rattus norvegicus 63911 R-SSC-211950 https://reactome.org/PathwayBrowser/#/R-SSC-211950 CYP24A1 24-hydroxylates CTL IEA Sus scrofa 63912 R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 63912 R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 63912 R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 63912 R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 63912 R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 63912 R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 63912 R-SSC-211919 https://reactome.org/PathwayBrowser/#/R-SSC-211919 CYP4F8 19-hydroxylates PGH2 IEA Sus scrofa 63912 R-XTR-211919 https://reactome.org/PathwayBrowser/#/R-XTR-211919 CYP4F8 19-hydroxylates PGH2 IEA Xenopus tropicalis 63914 R-BTA-389986 https://reactome.org/PathwayBrowser/#/R-BTA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Bos taurus 63914 R-BTA-389995 https://reactome.org/PathwayBrowser/#/R-BTA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Bos taurus 63914 R-CEL-389986 https://reactome.org/PathwayBrowser/#/R-CEL-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Caenorhabditis elegans 63914 R-CEL-389995 https://reactome.org/PathwayBrowser/#/R-CEL-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Caenorhabditis elegans 63914 R-CFA-389986 https://reactome.org/PathwayBrowser/#/R-CFA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Canis familiaris 63914 R-CFA-389995 https://reactome.org/PathwayBrowser/#/R-CFA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Canis familiaris 63914 R-DDI-389986 https://reactome.org/PathwayBrowser/#/R-DDI-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Dictyostelium discoideum 63914 R-DDI-389995 https://reactome.org/PathwayBrowser/#/R-DDI-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Dictyostelium discoideum 63914 R-DME-389986 https://reactome.org/PathwayBrowser/#/R-DME-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Drosophila melanogaster 63914 R-DME-389995 https://reactome.org/PathwayBrowser/#/R-DME-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Drosophila melanogaster 63914 R-GGA-389986 https://reactome.org/PathwayBrowser/#/R-GGA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Gallus gallus 63914 R-GGA-389995 https://reactome.org/PathwayBrowser/#/R-GGA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Gallus gallus 63914 R-HSA-389986 https://reactome.org/PathwayBrowser/#/R-HSA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA TAS Homo sapiens 63914 R-HSA-389995 https://reactome.org/PathwayBrowser/#/R-HSA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ TAS Homo sapiens 63914 R-MMU-389986 https://reactome.org/PathwayBrowser/#/R-MMU-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Mus musculus 63914 R-MMU-389995 https://reactome.org/PathwayBrowser/#/R-MMU-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Mus musculus 63914 R-RNO-389986 https://reactome.org/PathwayBrowser/#/R-RNO-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Rattus norvegicus 63914 R-RNO-389995 https://reactome.org/PathwayBrowser/#/R-RNO-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Rattus norvegicus 63916 R-BTA-9726949 https://reactome.org/PathwayBrowser/#/R-BTA-9726949 PTGIR binds PTGIR agonists IEA Bos taurus 63916 R-CFA-9726949 https://reactome.org/PathwayBrowser/#/R-CFA-9726949 PTGIR binds PTGIR agonists IEA Canis familiaris 63916 R-DME-9726949 https://reactome.org/PathwayBrowser/#/R-DME-9726949 PTGIR binds PTGIR agonists IEA Drosophila melanogaster 63916 R-DRE-9726949 https://reactome.org/PathwayBrowser/#/R-DRE-9726949 PTGIR binds PTGIR agonists IEA Danio rerio 63916 R-HSA-9726949 https://reactome.org/PathwayBrowser/#/R-HSA-9726949 PTGIR binds PTGIR agonists TAS Homo sapiens 63916 R-MMU-9726949 https://reactome.org/PathwayBrowser/#/R-MMU-9726949 PTGIR binds PTGIR agonists IEA Mus musculus 63916 R-RNO-9726949 https://reactome.org/PathwayBrowser/#/R-RNO-9726949 PTGIR binds PTGIR agonists IEA Rattus norvegicus 63916 R-SSC-9726949 https://reactome.org/PathwayBrowser/#/R-SSC-9726949 PTGIR binds PTGIR agonists IEA Sus scrofa 63916 R-XTR-9726949 https://reactome.org/PathwayBrowser/#/R-XTR-9726949 PTGIR binds PTGIR agonists IEA Xenopus tropicalis 63925 R-BTA-9718020 https://reactome.org/PathwayBrowser/#/R-BTA-9718020 PTGFR binds PTGFR agonists IEA Bos taurus 63925 R-CFA-9718020 https://reactome.org/PathwayBrowser/#/R-CFA-9718020 PTGFR binds PTGFR agonists IEA Canis familiaris 63925 R-DME-9718020 https://reactome.org/PathwayBrowser/#/R-DME-9718020 PTGFR binds PTGFR agonists IEA Drosophila melanogaster 63925 R-DRE-9718020 https://reactome.org/PathwayBrowser/#/R-DRE-9718020 PTGFR binds PTGFR agonists IEA Danio rerio 63925 R-GGA-9718020 https://reactome.org/PathwayBrowser/#/R-GGA-9718020 PTGFR binds PTGFR agonists IEA Gallus gallus 63925 R-HSA-9718020 https://reactome.org/PathwayBrowser/#/R-HSA-9718020 PTGFR binds PTGFR agonists TAS Homo sapiens 63925 R-MMU-9718020 https://reactome.org/PathwayBrowser/#/R-MMU-9718020 PTGFR binds PTGFR agonists IEA Mus musculus 63925 R-RNO-9718020 https://reactome.org/PathwayBrowser/#/R-RNO-9718020 PTGFR binds PTGFR agonists IEA Rattus norvegicus 63925 R-SSC-9718020 https://reactome.org/PathwayBrowser/#/R-SSC-9718020 PTGFR binds PTGFR agonists IEA Sus scrofa 63925 R-XTR-9718020 https://reactome.org/PathwayBrowser/#/R-XTR-9718020 PTGFR binds PTGFR agonists IEA Xenopus tropicalis 63966 R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Bos taurus 63966 R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Canis familiaris 63966 R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Dictyostelium discoideum 63966 R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Danio rerio 63966 R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Gallus gallus 63966 R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 TAS Homo sapiens 63966 R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Mus musculus 63966 R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Plasmodium falciparum 63966 R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Rattus norvegicus 63966 R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Sus scrofa 63966 R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Xenopus tropicalis 63969 R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Bos taurus 63969 R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Canis familiaris 63969 R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Dictyostelium discoideum 63969 R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Danio rerio 63969 R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Gallus gallus 63969 R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 TAS Homo sapiens 63969 R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Mus musculus 63969 R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Plasmodium falciparum 63969 R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Rattus norvegicus 63969 R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Sus scrofa 63969 R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Xenopus tropicalis 63970 R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Bos taurus 63970 R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Canis familiaris 63970 R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Dictyostelium discoideum 63970 R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Danio rerio 63970 R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Gallus gallus 63970 R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 TAS Homo sapiens 63970 R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Mus musculus 63970 R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Plasmodium falciparum 63970 R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Rattus norvegicus 63970 R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Sus scrofa 63970 R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Xenopus tropicalis 63974 R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Bos taurus 63974 R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Canis familiaris 63974 R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Dictyostelium discoideum 63974 R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Danio rerio 63974 R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Gallus gallus 63974 R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 TAS Homo sapiens 63974 R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Mus musculus 63974 R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Plasmodium falciparum 63974 R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Rattus norvegicus 63974 R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Sus scrofa 63974 R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 EET(1) is hydrolysed to DHET(1) by EPHX2 IEA Xenopus tropicalis 63975 R-HSA-2161668 https://reactome.org/PathwayBrowser/#/R-HSA-2161668 PGA2 is dehydrated to 15d-PGA2 IEA Homo sapiens 63975 R-MMU-2161646 https://reactome.org/PathwayBrowser/#/R-MMU-2161646 PGA2 is dehydrated to 15d-PGA2 TAS Mus musculus 63976 R-HSA-2161692 https://reactome.org/PathwayBrowser/#/R-HSA-2161692 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1 IEA Homo sapiens 63976 R-MMU-2161638 https://reactome.org/PathwayBrowser/#/R-MMU-2161638 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by Ptgr2 TAS Mus musculus 63977 R-BTA-2161613 https://reactome.org/PathwayBrowser/#/R-BTA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Bos taurus 63977 R-CFA-2161613 https://reactome.org/PathwayBrowser/#/R-CFA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Canis familiaris 63977 R-GGA-2161613 https://reactome.org/PathwayBrowser/#/R-GGA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Gallus gallus 63977 R-HSA-2161613 https://reactome.org/PathwayBrowser/#/R-HSA-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 TAS Homo sapiens 63977 R-MMU-2161613 https://reactome.org/PathwayBrowser/#/R-MMU-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Mus musculus 63977 R-RNO-2161613 https://reactome.org/PathwayBrowser/#/R-RNO-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Rattus norvegicus 63977 R-SSC-2161613 https://reactome.org/PathwayBrowser/#/R-SSC-2161613 PGH2 is degraded to 12S-HHT and MDA by TBXAS1 IEA Sus scrofa 63979 R-BTA-2161745 https://reactome.org/PathwayBrowser/#/R-BTA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Bos taurus 63979 R-BTA-2161792 https://reactome.org/PathwayBrowser/#/R-BTA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Bos taurus 63979 R-CFA-2161745 https://reactome.org/PathwayBrowser/#/R-CFA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Canis familiaris 63979 R-CFA-2161792 https://reactome.org/PathwayBrowser/#/R-CFA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Canis familiaris 63979 R-DRE-2161745 https://reactome.org/PathwayBrowser/#/R-DRE-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Danio rerio 63979 R-DRE-2161792 https://reactome.org/PathwayBrowser/#/R-DRE-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Danio rerio 63979 R-HSA-2161745 https://reactome.org/PathwayBrowser/#/R-HSA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 TAS Homo sapiens 63979 R-HSA-2161792 https://reactome.org/PathwayBrowser/#/R-HSA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 TAS Homo sapiens 63979 R-HSA-2161979 https://reactome.org/PathwayBrowser/#/R-HSA-2161979 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH TAS Homo sapiens 63979 R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus 63979 R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus 63979 R-RNO-2161745 https://reactome.org/PathwayBrowser/#/R-RNO-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 63979 R-RNO-2161792 https://reactome.org/PathwayBrowser/#/R-RNO-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 63979 R-SSC-2161745 https://reactome.org/PathwayBrowser/#/R-SSC-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Sus scrofa 63979 R-SSC-2161792 https://reactome.org/PathwayBrowser/#/R-SSC-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Sus scrofa 63979 R-XTR-2161745 https://reactome.org/PathwayBrowser/#/R-XTR-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 63979 R-XTR-2161792 https://reactome.org/PathwayBrowser/#/R-XTR-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 63980 R-HSA-2161790 https://reactome.org/PathwayBrowser/#/R-HSA-2161790 20cooh-LTB4 is converted to 18cooh-LTB4 TAS Homo sapiens 63981 R-HSA-2161962 https://reactome.org/PathwayBrowser/#/R-HSA-2161962 LTA4 is hydrolysed to 6t-/6t,12epi-LTB4 TAS Homo sapiens 63982 R-HSA-2161962 https://reactome.org/PathwayBrowser/#/R-HSA-2161962 LTA4 is hydrolysed to 6t-/6t,12epi-LTB4 TAS Homo sapiens 63983 R-BTA-2161768 https://reactome.org/PathwayBrowser/#/R-BTA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Bos taurus 63983 R-BTA-2162019 https://reactome.org/PathwayBrowser/#/R-BTA-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Bos taurus 63983 R-CFA-2161768 https://reactome.org/PathwayBrowser/#/R-CFA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Canis familiaris 63983 R-CFA-2162019 https://reactome.org/PathwayBrowser/#/R-CFA-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Canis familiaris 63983 R-DDI-2161768 https://reactome.org/PathwayBrowser/#/R-DDI-2161768 EXA4 is converted to EXC4 by LTC4S IEA Dictyostelium discoideum 63983 R-DDI-2162019 https://reactome.org/PathwayBrowser/#/R-DDI-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Dictyostelium discoideum 63983 R-DRE-2162019 https://reactome.org/PathwayBrowser/#/R-DRE-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Danio rerio 63983 R-GGA-2161768 https://reactome.org/PathwayBrowser/#/R-GGA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Gallus gallus 63983 R-HSA-2161768 https://reactome.org/PathwayBrowser/#/R-HSA-2161768 EXA4 is converted to EXC4 by LTC4S TAS Homo sapiens 63983 R-HSA-2162019 https://reactome.org/PathwayBrowser/#/R-HSA-2162019 LTA4 is converted to EXA4 by ALOX15 TAS Homo sapiens 63983 R-MMU-2161768 https://reactome.org/PathwayBrowser/#/R-MMU-2161768 EXA4 is converted to EXC4 by LTC4S IEA Mus musculus 63983 R-MMU-2162019 https://reactome.org/PathwayBrowser/#/R-MMU-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Mus musculus 63983 R-RNO-2161768 https://reactome.org/PathwayBrowser/#/R-RNO-2161768 EXA4 is converted to EXC4 by LTC4S IEA Rattus norvegicus 63983 R-RNO-2162019 https://reactome.org/PathwayBrowser/#/R-RNO-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Rattus norvegicus 63983 R-SSC-2161768 https://reactome.org/PathwayBrowser/#/R-SSC-2161768 EXA4 is converted to EXC4 by LTC4S IEA Sus scrofa 63983 R-SSC-2162019 https://reactome.org/PathwayBrowser/#/R-SSC-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Sus scrofa 63983 R-XTR-2161768 https://reactome.org/PathwayBrowser/#/R-XTR-2161768 EXA4 is converted to EXC4 by LTC4S IEA Xenopus tropicalis 63984 R-BTA-2161768 https://reactome.org/PathwayBrowser/#/R-BTA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Bos taurus 63984 R-CFA-2161768 https://reactome.org/PathwayBrowser/#/R-CFA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Canis familiaris 63984 R-DDI-2161768 https://reactome.org/PathwayBrowser/#/R-DDI-2161768 EXA4 is converted to EXC4 by LTC4S IEA Dictyostelium discoideum 63984 R-GGA-2161768 https://reactome.org/PathwayBrowser/#/R-GGA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Gallus gallus 63984 R-HSA-2161768 https://reactome.org/PathwayBrowser/#/R-HSA-2161768 EXA4 is converted to EXC4 by LTC4S TAS Homo sapiens 63984 R-HSA-2161945 https://reactome.org/PathwayBrowser/#/R-HSA-2161945 EXC4 is converted to EXD4 by GGT TAS Homo sapiens 63984 R-MMU-2161768 https://reactome.org/PathwayBrowser/#/R-MMU-2161768 EXA4 is converted to EXC4 by LTC4S IEA Mus musculus 63984 R-RNO-2161768 https://reactome.org/PathwayBrowser/#/R-RNO-2161768 EXA4 is converted to EXC4 by LTC4S IEA Rattus norvegicus 63984 R-SSC-2161768 https://reactome.org/PathwayBrowser/#/R-SSC-2161768 EXA4 is converted to EXC4 by LTC4S IEA Sus scrofa 63984 R-XTR-2161768 https://reactome.org/PathwayBrowser/#/R-XTR-2161768 EXA4 is converted to EXC4 by LTC4S IEA Xenopus tropicalis 63985 R-HSA-2161868 https://reactome.org/PathwayBrowser/#/R-HSA-2161868 EXD4 is converted to EXE4 by DPEP TAS Homo sapiens 63985 R-HSA-2161945 https://reactome.org/PathwayBrowser/#/R-HSA-2161945 EXC4 is converted to EXD4 by GGT TAS Homo sapiens 63986 R-HSA-2161868 https://reactome.org/PathwayBrowser/#/R-HSA-2161868 EXD4 is converted to EXE4 by DPEP TAS Homo sapiens 63989 R-BTA-2161907 https://reactome.org/PathwayBrowser/#/R-BTA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Bos taurus 63989 R-BTA-2161951 https://reactome.org/PathwayBrowser/#/R-BTA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Bos taurus 63989 R-CFA-2161907 https://reactome.org/PathwayBrowser/#/R-CFA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Canis familiaris 63989 R-CFA-2161951 https://reactome.org/PathwayBrowser/#/R-CFA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Canis familiaris 63989 R-DDI-2161907 https://reactome.org/PathwayBrowser/#/R-DDI-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Dictyostelium discoideum 63989 R-DRE-2161951 https://reactome.org/PathwayBrowser/#/R-DRE-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Danio rerio 63989 R-GGA-2161907 https://reactome.org/PathwayBrowser/#/R-GGA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Gallus gallus 63989 R-GGA-2161951 https://reactome.org/PathwayBrowser/#/R-GGA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Gallus gallus 63989 R-HSA-2161907 https://reactome.org/PathwayBrowser/#/R-HSA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 TAS Homo sapiens 63989 R-HSA-2161951 https://reactome.org/PathwayBrowser/#/R-HSA-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 TAS Homo sapiens 63989 R-MMU-2161907 https://reactome.org/PathwayBrowser/#/R-MMU-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Mus musculus 63989 R-MMU-2161951 https://reactome.org/PathwayBrowser/#/R-MMU-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Mus musculus 63989 R-RNO-2161907 https://reactome.org/PathwayBrowser/#/R-RNO-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Rattus norvegicus 63989 R-RNO-2161951 https://reactome.org/PathwayBrowser/#/R-RNO-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Rattus norvegicus 63989 R-SSC-2161907 https://reactome.org/PathwayBrowser/#/R-SSC-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Sus scrofa 63989 R-SSC-2161951 https://reactome.org/PathwayBrowser/#/R-SSC-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Sus scrofa 63989 R-XTR-2161907 https://reactome.org/PathwayBrowser/#/R-XTR-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Xenopus tropicalis 63989 R-XTR-2161951 https://reactome.org/PathwayBrowser/#/R-XTR-2161951 Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Xenopus tropicalis 63990 R-BTA-2161907 https://reactome.org/PathwayBrowser/#/R-BTA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Bos taurus 63990 R-CFA-2161907 https://reactome.org/PathwayBrowser/#/R-CFA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Canis familiaris 63990 R-DDI-2161907 https://reactome.org/PathwayBrowser/#/R-DDI-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Dictyostelium discoideum 63990 R-GGA-2161907 https://reactome.org/PathwayBrowser/#/R-GGA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Gallus gallus 63990 R-HSA-2161907 https://reactome.org/PathwayBrowser/#/R-HSA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 TAS Homo sapiens 63990 R-MMU-2161907 https://reactome.org/PathwayBrowser/#/R-MMU-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Mus musculus 63990 R-RNO-2161907 https://reactome.org/PathwayBrowser/#/R-RNO-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Rattus norvegicus 63990 R-SSC-2161907 https://reactome.org/PathwayBrowser/#/R-SSC-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Sus scrofa 63990 R-XTR-2161907 https://reactome.org/PathwayBrowser/#/R-XTR-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Xenopus tropicalis 63991 R-BTA-2161907 https://reactome.org/PathwayBrowser/#/R-BTA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Bos taurus 63991 R-CFA-2161907 https://reactome.org/PathwayBrowser/#/R-CFA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Canis familiaris 63991 R-DDI-2161907 https://reactome.org/PathwayBrowser/#/R-DDI-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Dictyostelium discoideum 63991 R-GGA-2161907 https://reactome.org/PathwayBrowser/#/R-GGA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Gallus gallus 63991 R-HSA-2161907 https://reactome.org/PathwayBrowser/#/R-HSA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 TAS Homo sapiens 63991 R-MMU-2161907 https://reactome.org/PathwayBrowser/#/R-MMU-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Mus musculus 63991 R-RNO-2161907 https://reactome.org/PathwayBrowser/#/R-RNO-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Rattus norvegicus 63991 R-SSC-2161907 https://reactome.org/PathwayBrowser/#/R-SSC-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Sus scrofa 63991 R-XTR-2161907 https://reactome.org/PathwayBrowser/#/R-XTR-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Xenopus tropicalis 63992 R-BTA-2161779 https://reactome.org/PathwayBrowser/#/R-BTA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Bos taurus 63992 R-CFA-2161779 https://reactome.org/PathwayBrowser/#/R-CFA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Canis familiaris 63992 R-DME-2161779 https://reactome.org/PathwayBrowser/#/R-DME-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Drosophila melanogaster 63992 R-DRE-2161779 https://reactome.org/PathwayBrowser/#/R-DRE-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Danio rerio 63992 R-GGA-2161779 https://reactome.org/PathwayBrowser/#/R-GGA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Gallus gallus 63992 R-HSA-2161779 https://reactome.org/PathwayBrowser/#/R-HSA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD TAS Homo sapiens 63992 R-HSA-2161844 https://reactome.org/PathwayBrowser/#/R-HSA-2161844 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 IEA Homo sapiens 63992 R-MMU-2161779 https://reactome.org/PathwayBrowser/#/R-MMU-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Mus musculus 63992 R-RNO-2161779 https://reactome.org/PathwayBrowser/#/R-RNO-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Rattus norvegicus 63992 R-SSC-2161779 https://reactome.org/PathwayBrowser/#/R-SSC-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Sus scrofa 63992 R-SSC-2161847 https://reactome.org/PathwayBrowser/#/R-SSC-2161847 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 TAS Sus scrofa 63992 R-XTR-2161779 https://reactome.org/PathwayBrowser/#/R-XTR-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Xenopus tropicalis 63993 R-HSA-2161844 https://reactome.org/PathwayBrowser/#/R-HSA-2161844 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 IEA Homo sapiens 63993 R-SSC-2161847 https://reactome.org/PathwayBrowser/#/R-SSC-2161847 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 TAS Sus scrofa 63994 R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Bos taurus 63994 R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Canis familiaris 63994 R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Danio rerio 63994 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Gallus gallus 63994 R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) TAS Homo sapiens 63994 R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Mus musculus 63994 R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Rattus norvegicus 63994 R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Sus scrofa 63995 R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Bos taurus 63995 R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Canis familiaris 63995 R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Danio rerio 63995 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Gallus gallus 63995 R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) TAS Homo sapiens 63995 R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Mus musculus 63995 R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Rattus norvegicus 63995 R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) IEA Sus scrofa 63998 R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 63998 R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 63998 R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 63998 R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 63998 R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 63998 R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 63998 R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 63998 R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 63998 R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 63998 R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 63998 R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 63998 R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 63998 R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 63998 R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 63998 R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 63998 R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 63998 R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 63998 R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa 63998 R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa 63998 R-XTR-211960 https://reactome.org/PathwayBrowser/#/R-XTR-211960 CYP2U1 19-hydroxylates ARA IEA Xenopus tropicalis 63998 R-XTR-2161814 https://reactome.org/PathwayBrowser/#/R-XTR-2161814 Arachidonic acid is hydroxylated to 19-HETE by CYP(2) IEA Xenopus tropicalis 63999 R-HSA-2161673 https://reactome.org/PathwayBrowser/#/R-HSA-2161673 PGD2 is dehydrated to 15d-PGD2 TAS Homo sapiens 64009 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 64009 R-BTA-2197646 https://reactome.org/PathwayBrowser/#/R-BTA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Bos taurus 64009 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 64009 R-BTA-2512800 https://reactome.org/PathwayBrowser/#/R-BTA-2512800 SCARB1:ligand is endocytosed IEA Bos taurus 64009 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 64009 R-BTA-8869667 https://reactome.org/PathwayBrowser/#/R-BTA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Bos taurus 64009 R-CFA-2197646 https://reactome.org/PathwayBrowser/#/R-CFA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Canis familiaris 64009 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 64009 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 64009 R-CFA-2512800 https://reactome.org/PathwayBrowser/#/R-CFA-2512800 SCARB1:ligand is endocytosed IEA Canis familiaris 64009 R-GGA-2197646 https://reactome.org/PathwayBrowser/#/R-GGA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Gallus gallus 64009 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 64009 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 64009 R-GGA-2512800 https://reactome.org/PathwayBrowser/#/R-GGA-2512800 SCARB1:ligand is endocytosed IEA Gallus gallus 64009 R-GGA-8869667 https://reactome.org/PathwayBrowser/#/R-GGA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Gallus gallus 64009 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 64009 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 64009 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 64009 R-HSA-2197645 https://reactome.org/PathwayBrowser/#/R-HSA-2197645 SCARF1 (SREC-I) binds ligands IEA Homo sapiens 64009 R-HSA-2197646 https://reactome.org/PathwayBrowser/#/R-HSA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands TAS Homo sapiens 64009 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 64009 R-HSA-2247514 https://reactome.org/PathwayBrowser/#/R-HSA-2247514 SCARF1:ligand is endocytosed TAS Homo sapiens 64009 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 64009 R-HSA-2512800 https://reactome.org/PathwayBrowser/#/R-HSA-2512800 SCARB1:ligand is endocytosed TAS Homo sapiens 64009 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 64009 R-HSA-8869667 https://reactome.org/PathwayBrowser/#/R-HSA-8869667 oxLDL:CD36 binds TLR4:TLR6 TAS Homo sapiens 64009 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 64009 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 64009 R-MMU-2197646 https://reactome.org/PathwayBrowser/#/R-MMU-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Mus musculus 64009 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 64009 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 64009 R-MMU-2512800 https://reactome.org/PathwayBrowser/#/R-MMU-2512800 SCARB1:ligand is endocytosed IEA Mus musculus 64009 R-MMU-8869667 https://reactome.org/PathwayBrowser/#/R-MMU-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Mus musculus 64009 R-RNO-2197646 https://reactome.org/PathwayBrowser/#/R-RNO-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Rattus norvegicus 64009 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 64009 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 64009 R-RNO-2512800 https://reactome.org/PathwayBrowser/#/R-RNO-2512800 SCARB1:ligand is endocytosed IEA Rattus norvegicus 64009 R-RNO-8869667 https://reactome.org/PathwayBrowser/#/R-RNO-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Rattus norvegicus 64009 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa 64009 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 64009 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 64009 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa 64009 R-SSC-8869667 https://reactome.org/PathwayBrowser/#/R-SSC-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Sus scrofa 64012 R-HSA-1222341 https://reactome.org/PathwayBrowser/#/R-HSA-1222341 H2O2 gets scavenged by unsaturated lipid TAS Homo sapiens 64012 R-HSA-1222526 https://reactome.org/PathwayBrowser/#/R-HSA-1222526 AhpC reduces peroxidated lipids TAS Homo sapiens 64012 R-HSA-6789042 https://reactome.org/PathwayBrowser/#/R-HSA-6789042 Hydroxyl-initiated lipid peroxidation TAS Homo sapiens 64022 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 64022 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 64022 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 64022 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 64022 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 64022 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 64022 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 64022 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 64022 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 64022 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 64022 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 64022 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 64022 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 64022 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 64022 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 64022 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 64022 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 64022 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 64022 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 64022 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 64022 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 64022 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 64022 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 64022 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 64022 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 64022 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 64022 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 64022 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 64022 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 64022 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 64022 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 64022 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 64022 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 64022 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 64022 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 64022 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 64022 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 64024 R-BTA-2142859 https://reactome.org/PathwayBrowser/#/R-BTA-2142859 Growing HA is extruded from the cell by ABCC5 IEA Bos taurus 64024 R-BTA-2160851 https://reactome.org/PathwayBrowser/#/R-BTA-2160851 HAS1,2,3 mediate the polymerization of HA IEA Bos taurus 64024 R-BTA-2160874 https://reactome.org/PathwayBrowser/#/R-BTA-2160874 HYAL1 hydrolyses (HA)50 IEA Bos taurus 64024 R-BTA-2160884 https://reactome.org/PathwayBrowser/#/R-BTA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Bos taurus 64024 R-BTA-2160892 https://reactome.org/PathwayBrowser/#/R-BTA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Bos taurus 64024 R-BTA-2160915 https://reactome.org/PathwayBrowser/#/R-BTA-2160915 Receptor-mediated uptake of HA IEA Bos taurus 64024 R-BTA-2162225 https://reactome.org/PathwayBrowser/#/R-BTA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Bos taurus 64024 R-BTA-2162226 https://reactome.org/PathwayBrowser/#/R-BTA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Bos taurus 64024 R-BTA-2162227 https://reactome.org/PathwayBrowser/#/R-BTA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Bos taurus 64024 R-BTA-2318623 https://reactome.org/PathwayBrowser/#/R-BTA-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Bos taurus 64024 R-BTA-5693356 https://reactome.org/PathwayBrowser/#/R-BTA-5693356 CEMIP hydrolyses HA IEA Bos taurus 64024 R-BTA-9638076 https://reactome.org/PathwayBrowser/#/R-BTA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Bos taurus 64024 R-CEL-2142859 https://reactome.org/PathwayBrowser/#/R-CEL-2142859 Growing HA is extruded from the cell by ABCC5 IEA Caenorhabditis elegans 64024 R-CEL-2160874 https://reactome.org/PathwayBrowser/#/R-CEL-2160874 HYAL1 hydrolyses (HA)50 IEA Caenorhabditis elegans 64024 R-CEL-2160892 https://reactome.org/PathwayBrowser/#/R-CEL-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Caenorhabditis elegans 64024 R-CEL-2162225 https://reactome.org/PathwayBrowser/#/R-CEL-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Caenorhabditis elegans 64024 R-CEL-2162226 https://reactome.org/PathwayBrowser/#/R-CEL-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Caenorhabditis elegans 64024 R-CEL-2162227 https://reactome.org/PathwayBrowser/#/R-CEL-2162227 GUSB tetramer hydrolyses (HA)2 IEA Caenorhabditis elegans 64024 R-CEL-9638076 https://reactome.org/PathwayBrowser/#/R-CEL-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Caenorhabditis elegans 64024 R-CFA-2142859 https://reactome.org/PathwayBrowser/#/R-CFA-2142859 Growing HA is extruded from the cell by ABCC5 IEA Canis familiaris 64024 R-CFA-2160851 https://reactome.org/PathwayBrowser/#/R-CFA-2160851 HAS1,2,3 mediate the polymerization of HA IEA Canis familiaris 64024 R-CFA-2160874 https://reactome.org/PathwayBrowser/#/R-CFA-2160874 HYAL1 hydrolyses (HA)50 IEA Canis familiaris 64024 R-CFA-2160892 https://reactome.org/PathwayBrowser/#/R-CFA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Canis familiaris 64024 R-CFA-2162225 https://reactome.org/PathwayBrowser/#/R-CFA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Canis familiaris 64024 R-CFA-2162226 https://reactome.org/PathwayBrowser/#/R-CFA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Canis familiaris 64024 R-CFA-2162227 https://reactome.org/PathwayBrowser/#/R-CFA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Canis familiaris 64024 R-CFA-2318623 https://reactome.org/PathwayBrowser/#/R-CFA-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Canis familiaris 64024 R-CFA-5693356 https://reactome.org/PathwayBrowser/#/R-CFA-5693356 CEMIP hydrolyses HA IEA Canis familiaris 64024 R-CFA-9638076 https://reactome.org/PathwayBrowser/#/R-CFA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Canis familiaris 64024 R-DDI-2162225 https://reactome.org/PathwayBrowser/#/R-DDI-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Dictyostelium discoideum 64024 R-DDI-5693356 https://reactome.org/PathwayBrowser/#/R-DDI-5693356 CEMIP hydrolyses HA IEA Dictyostelium discoideum 64024 R-DDI-9638076 https://reactome.org/PathwayBrowser/#/R-DDI-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Dictyostelium discoideum 64024 R-DME-2162225 https://reactome.org/PathwayBrowser/#/R-DME-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Drosophila melanogaster 64024 R-DME-2162226 https://reactome.org/PathwayBrowser/#/R-DME-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Drosophila melanogaster 64024 R-DME-2162227 https://reactome.org/PathwayBrowser/#/R-DME-2162227 GUSB tetramer hydrolyses (HA)2 IEA Drosophila melanogaster 64024 R-DME-9638076 https://reactome.org/PathwayBrowser/#/R-DME-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Drosophila melanogaster 64024 R-DRE-2142859 https://reactome.org/PathwayBrowser/#/R-DRE-2142859 Growing HA is extruded from the cell by ABCC5 IEA Danio rerio 64024 R-DRE-2160874 https://reactome.org/PathwayBrowser/#/R-DRE-2160874 HYAL1 hydrolyses (HA)50 IEA Danio rerio 64024 R-GGA-2142859 https://reactome.org/PathwayBrowser/#/R-GGA-2142859 Growing HA is extruded from the cell by ABCC5 IEA Gallus gallus 64024 R-GGA-2160851 https://reactome.org/PathwayBrowser/#/R-GGA-2160851 HAS1,2,3 mediate the polymerization of HA IEA Gallus gallus 64024 R-GGA-2160874 https://reactome.org/PathwayBrowser/#/R-GGA-2160874 HYAL1 hydrolyses (HA)50 IEA Gallus gallus 64024 R-GGA-2160884 https://reactome.org/PathwayBrowser/#/R-GGA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Gallus gallus 64024 R-GGA-2160892 https://reactome.org/PathwayBrowser/#/R-GGA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Gallus gallus 64024 R-GGA-2160915 https://reactome.org/PathwayBrowser/#/R-GGA-2160915 Receptor-mediated uptake of HA IEA Gallus gallus 64024 R-GGA-2162225 https://reactome.org/PathwayBrowser/#/R-GGA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Gallus gallus 64024 R-GGA-2162226 https://reactome.org/PathwayBrowser/#/R-GGA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Gallus gallus 64024 R-GGA-2162227 https://reactome.org/PathwayBrowser/#/R-GGA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Gallus gallus 64024 R-GGA-2318623 https://reactome.org/PathwayBrowser/#/R-GGA-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Gallus gallus 64024 R-GGA-5693356 https://reactome.org/PathwayBrowser/#/R-GGA-5693356 CEMIP hydrolyses HA IEA Gallus gallus 64024 R-GGA-9638076 https://reactome.org/PathwayBrowser/#/R-GGA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Gallus gallus 64024 R-HSA-2142859 https://reactome.org/PathwayBrowser/#/R-HSA-2142859 Growing HA is extruded from the cell by ABCC5 TAS Homo sapiens 64024 R-HSA-2160851 https://reactome.org/PathwayBrowser/#/R-HSA-2160851 HAS1,2,3 mediate the polymerization of HA TAS Homo sapiens 64024 R-HSA-2160874 https://reactome.org/PathwayBrowser/#/R-HSA-2160874 HYAL1 hydrolyses (HA)50 TAS Homo sapiens 64024 R-HSA-2160884 https://reactome.org/PathwayBrowser/#/R-HSA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ TAS Homo sapiens 64024 R-HSA-2160892 https://reactome.org/PathwayBrowser/#/R-HSA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments TAS Homo sapiens 64024 R-HSA-2160906 https://reactome.org/PathwayBrowser/#/R-HSA-2160906 20kDa HA fragments are translocated to lysosomes TAS Homo sapiens 64024 R-HSA-2160915 https://reactome.org/PathwayBrowser/#/R-HSA-2160915 Receptor-mediated uptake of HA TAS Homo sapiens 64024 R-HSA-2162225 https://reactome.org/PathwayBrowser/#/R-HSA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments TAS Homo sapiens 64024 R-HSA-2162226 https://reactome.org/PathwayBrowser/#/R-HSA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc TAS Homo sapiens 64024 R-HSA-2162227 https://reactome.org/PathwayBrowser/#/R-HSA-2162227 GUSB tetramer hydrolyses (HA)2 TAS Homo sapiens 64024 R-HSA-2318373 https://reactome.org/PathwayBrowser/#/R-HSA-2318373 Defective GUSB does not hydrolyse (HA)2 TAS Homo sapiens 64024 R-HSA-2318623 https://reactome.org/PathwayBrowser/#/R-HSA-2318623 Aggrecan binds Hyaluronan and HAPLN1 TAS Homo sapiens 64024 R-HSA-5693356 https://reactome.org/PathwayBrowser/#/R-HSA-5693356 CEMIP hydrolyses HA TAS Homo sapiens 64024 R-HSA-9036068 https://reactome.org/PathwayBrowser/#/R-HSA-9036068 Defective GUSB does not hydrolyse GlcA-β1,3-GlcNAc TAS Homo sapiens 64024 R-HSA-9036077 https://reactome.org/PathwayBrowser/#/R-HSA-9036077 Defective HYAL1 does not hydrolyse (HA)50 TAS Homo sapiens 64024 R-HSA-9638076 https://reactome.org/PathwayBrowser/#/R-HSA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments TAS Homo sapiens 64024 R-MMU-2142859 https://reactome.org/PathwayBrowser/#/R-MMU-2142859 Growing HA is extruded from the cell by ABCC5 IEA Mus musculus 64024 R-MMU-2160851 https://reactome.org/PathwayBrowser/#/R-MMU-2160851 HAS1,2,3 mediate the polymerization of HA IEA Mus musculus 64024 R-MMU-2160874 https://reactome.org/PathwayBrowser/#/R-MMU-2160874 HYAL1 hydrolyses (HA)50 IEA Mus musculus 64024 R-MMU-2160884 https://reactome.org/PathwayBrowser/#/R-MMU-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Mus musculus 64024 R-MMU-2160892 https://reactome.org/PathwayBrowser/#/R-MMU-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Mus musculus 64024 R-MMU-2160915 https://reactome.org/PathwayBrowser/#/R-MMU-2160915 Receptor-mediated uptake of HA IEA Mus musculus 64024 R-MMU-2162225 https://reactome.org/PathwayBrowser/#/R-MMU-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Mus musculus 64024 R-MMU-2162226 https://reactome.org/PathwayBrowser/#/R-MMU-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Mus musculus 64024 R-MMU-2162227 https://reactome.org/PathwayBrowser/#/R-MMU-2162227 GUSB tetramer hydrolyses (HA)2 IEA Mus musculus 64024 R-MMU-2318623 https://reactome.org/PathwayBrowser/#/R-MMU-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Mus musculus 64024 R-MMU-5693356 https://reactome.org/PathwayBrowser/#/R-MMU-5693356 CEMIP hydrolyses HA IEA Mus musculus 64024 R-MMU-9638076 https://reactome.org/PathwayBrowser/#/R-MMU-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Mus musculus 64024 R-RNO-2142859 https://reactome.org/PathwayBrowser/#/R-RNO-2142859 Growing HA is extruded from the cell by ABCC5 IEA Rattus norvegicus 64024 R-RNO-2160851 https://reactome.org/PathwayBrowser/#/R-RNO-2160851 HAS1,2,3 mediate the polymerization of HA IEA Rattus norvegicus 64024 R-RNO-2160874 https://reactome.org/PathwayBrowser/#/R-RNO-2160874 HYAL1 hydrolyses (HA)50 IEA Rattus norvegicus 64024 R-RNO-2160884 https://reactome.org/PathwayBrowser/#/R-RNO-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Rattus norvegicus 64024 R-RNO-2160892 https://reactome.org/PathwayBrowser/#/R-RNO-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Rattus norvegicus 64024 R-RNO-2160915 https://reactome.org/PathwayBrowser/#/R-RNO-2160915 Receptor-mediated uptake of HA IEA Rattus norvegicus 64024 R-RNO-2162225 https://reactome.org/PathwayBrowser/#/R-RNO-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Rattus norvegicus 64024 R-RNO-2162226 https://reactome.org/PathwayBrowser/#/R-RNO-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Rattus norvegicus 64024 R-RNO-2162227 https://reactome.org/PathwayBrowser/#/R-RNO-2162227 GUSB tetramer hydrolyses (HA)2 IEA Rattus norvegicus 64024 R-RNO-2318623 https://reactome.org/PathwayBrowser/#/R-RNO-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Rattus norvegicus 64024 R-RNO-5693356 https://reactome.org/PathwayBrowser/#/R-RNO-5693356 CEMIP hydrolyses HA IEA Rattus norvegicus 64024 R-RNO-9638076 https://reactome.org/PathwayBrowser/#/R-RNO-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Rattus norvegicus 64024 R-SSC-2142859 https://reactome.org/PathwayBrowser/#/R-SSC-2142859 Growing HA is extruded from the cell by ABCC5 IEA Sus scrofa 64024 R-SSC-2160851 https://reactome.org/PathwayBrowser/#/R-SSC-2160851 HAS1,2,3 mediate the polymerization of HA IEA Sus scrofa 64024 R-SSC-2160874 https://reactome.org/PathwayBrowser/#/R-SSC-2160874 HYAL1 hydrolyses (HA)50 IEA Sus scrofa 64024 R-SSC-2160884 https://reactome.org/PathwayBrowser/#/R-SSC-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Sus scrofa 64024 R-SSC-2160892 https://reactome.org/PathwayBrowser/#/R-SSC-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Sus scrofa 64024 R-SSC-2160915 https://reactome.org/PathwayBrowser/#/R-SSC-2160915 Receptor-mediated uptake of HA IEA Sus scrofa 64024 R-SSC-2162225 https://reactome.org/PathwayBrowser/#/R-SSC-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Sus scrofa 64024 R-SSC-2162226 https://reactome.org/PathwayBrowser/#/R-SSC-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Sus scrofa 64024 R-SSC-2162227 https://reactome.org/PathwayBrowser/#/R-SSC-2162227 GUSB tetramer hydrolyses (HA)2 IEA Sus scrofa 64024 R-SSC-2318623 https://reactome.org/PathwayBrowser/#/R-SSC-2318623 Aggrecan binds Hyaluronan and HAPLN1 IEA Sus scrofa 64024 R-SSC-5693356 https://reactome.org/PathwayBrowser/#/R-SSC-5693356 CEMIP hydrolyses HA IEA Sus scrofa 64024 R-SSC-9638076 https://reactome.org/PathwayBrowser/#/R-SSC-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Sus scrofa 64024 R-XTR-2142859 https://reactome.org/PathwayBrowser/#/R-XTR-2142859 Growing HA is extruded from the cell by ABCC5 IEA Xenopus tropicalis 64024 R-XTR-2160851 https://reactome.org/PathwayBrowser/#/R-XTR-2160851 HAS1,2,3 mediate the polymerization of HA IEA Xenopus tropicalis 64024 R-XTR-2160874 https://reactome.org/PathwayBrowser/#/R-XTR-2160874 HYAL1 hydrolyses (HA)50 IEA Xenopus tropicalis 64024 R-XTR-2160892 https://reactome.org/PathwayBrowser/#/R-XTR-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Xenopus tropicalis 64024 R-XTR-2162226 https://reactome.org/PathwayBrowser/#/R-XTR-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Xenopus tropicalis 64024 R-XTR-2162227 https://reactome.org/PathwayBrowser/#/R-XTR-2162227 GUSB tetramer hydrolyses (HA)2 IEA Xenopus tropicalis 64024 R-XTR-9638076 https://reactome.org/PathwayBrowser/#/R-XTR-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Xenopus tropicalis 64039 R-BTA-389889 https://reactome.org/PathwayBrowser/#/R-BTA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Bos taurus 64039 R-BTA-389891 https://reactome.org/PathwayBrowser/#/R-BTA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Bos taurus 64039 R-BTA-389897 https://reactome.org/PathwayBrowser/#/R-BTA-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Bos taurus 64039 R-CEL-389889 https://reactome.org/PathwayBrowser/#/R-CEL-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Caenorhabditis elegans 64039 R-CEL-389891 https://reactome.org/PathwayBrowser/#/R-CEL-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Caenorhabditis elegans 64039 R-CEL-389897 https://reactome.org/PathwayBrowser/#/R-CEL-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Caenorhabditis elegans 64039 R-CFA-389889 https://reactome.org/PathwayBrowser/#/R-CFA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Canis familiaris 64039 R-CFA-389891 https://reactome.org/PathwayBrowser/#/R-CFA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Canis familiaris 64039 R-DDI-389889 https://reactome.org/PathwayBrowser/#/R-DDI-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Dictyostelium discoideum 64039 R-DDI-389891 https://reactome.org/PathwayBrowser/#/R-DDI-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Dictyostelium discoideum 64039 R-DME-389889 https://reactome.org/PathwayBrowser/#/R-DME-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Drosophila melanogaster 64039 R-DME-389891 https://reactome.org/PathwayBrowser/#/R-DME-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Drosophila melanogaster 64039 R-DME-389897 https://reactome.org/PathwayBrowser/#/R-DME-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Drosophila melanogaster 64039 R-DRE-389891 https://reactome.org/PathwayBrowser/#/R-DRE-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Danio rerio 64039 R-DRE-389897 https://reactome.org/PathwayBrowser/#/R-DRE-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Danio rerio 64039 R-GGA-389889 https://reactome.org/PathwayBrowser/#/R-GGA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Gallus gallus 64039 R-GGA-389891 https://reactome.org/PathwayBrowser/#/R-GGA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Gallus gallus 64039 R-GGA-389897 https://reactome.org/PathwayBrowser/#/R-GGA-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Gallus gallus 64039 R-HSA-389889 https://reactome.org/PathwayBrowser/#/R-HSA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA TAS Homo sapiens 64039 R-HSA-389891 https://reactome.org/PathwayBrowser/#/R-HSA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) TAS Homo sapiens 64039 R-HSA-389897 https://reactome.org/PathwayBrowser/#/R-HSA-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA TAS Homo sapiens 64039 R-MMU-389889 https://reactome.org/PathwayBrowser/#/R-MMU-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Mus musculus 64039 R-MMU-389891 https://reactome.org/PathwayBrowser/#/R-MMU-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Mus musculus 64039 R-MMU-389897 https://reactome.org/PathwayBrowser/#/R-MMU-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Mus musculus 64039 R-RNO-389889 https://reactome.org/PathwayBrowser/#/R-RNO-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Rattus norvegicus 64039 R-RNO-389891 https://reactome.org/PathwayBrowser/#/R-RNO-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Rattus norvegicus 64039 R-RNO-389897 https://reactome.org/PathwayBrowser/#/R-RNO-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Rattus norvegicus 64039 R-SCE-389891 https://reactome.org/PathwayBrowser/#/R-SCE-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Saccharomyces cerevisiae 64039 R-SSC-389889 https://reactome.org/PathwayBrowser/#/R-SSC-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Sus scrofa 64039 R-SSC-389891 https://reactome.org/PathwayBrowser/#/R-SSC-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Sus scrofa 64039 R-XTR-389889 https://reactome.org/PathwayBrowser/#/R-XTR-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Xenopus tropicalis 64039 R-XTR-389891 https://reactome.org/PathwayBrowser/#/R-XTR-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Xenopus tropicalis 64039 R-XTR-389897 https://reactome.org/PathwayBrowser/#/R-XTR-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA IEA Xenopus tropicalis 64043 R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 64043 R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 64043 R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 64043 R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 64043 R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 64043 R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 64043 R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 64043 R-SSC-211948 https://reactome.org/PathwayBrowser/#/R-SSC-211948 CYP3A4 can N-demethylate loperamide IEA Sus scrofa 64043 R-XTR-211948 https://reactome.org/PathwayBrowser/#/R-XTR-211948 CYP3A4 can N-demethylate loperamide IEA Xenopus tropicalis 64045 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 64045 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 64045 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 64045 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 64045 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 64045 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 64045 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 64045 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 64045 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 64045 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 64046 R-HSA-548884 https://reactome.org/PathwayBrowser/#/R-HSA-548884 UGGT1,2 transfers glucose from DbGP to (un)folded protein:(GlcNAc)2 (Man)8b TAS Homo sapiens 64046 R-HSA-548890 https://reactome.org/PathwayBrowser/#/R-HSA-548890 Removal of the third glucose by glucosidase II and release from the chaperone TAS Homo sapiens 64048 R-HSA-548890 https://reactome.org/PathwayBrowser/#/R-HSA-548890 Removal of the third glucose by glucosidase II and release from the chaperone TAS Homo sapiens 64052 R-HSA-548890 https://reactome.org/PathwayBrowser/#/R-HSA-548890 Removal of the third glucose by glucosidase II and release from the chaperone TAS Homo sapiens 64084 R-BTA-6806966 https://reactome.org/PathwayBrowser/#/R-BTA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Bos taurus 64084 R-BTA-6806967 https://reactome.org/PathwayBrowser/#/R-BTA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Bos taurus 64084 R-CEL-6806966 https://reactome.org/PathwayBrowser/#/R-CEL-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Caenorhabditis elegans 64084 R-CEL-6806967 https://reactome.org/PathwayBrowser/#/R-CEL-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Caenorhabditis elegans 64084 R-CFA-6806966 https://reactome.org/PathwayBrowser/#/R-CFA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Canis familiaris 64084 R-CFA-6806967 https://reactome.org/PathwayBrowser/#/R-CFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Canis familiaris 64084 R-DDI-6806966 https://reactome.org/PathwayBrowser/#/R-DDI-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Dictyostelium discoideum 64084 R-DDI-6806967 https://reactome.org/PathwayBrowser/#/R-DDI-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Dictyostelium discoideum 64084 R-DME-6806966 https://reactome.org/PathwayBrowser/#/R-DME-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Drosophila melanogaster 64084 R-DME-6806967 https://reactome.org/PathwayBrowser/#/R-DME-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Drosophila melanogaster 64084 R-DRE-6806966 https://reactome.org/PathwayBrowser/#/R-DRE-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Danio rerio 64084 R-DRE-6806967 https://reactome.org/PathwayBrowser/#/R-DRE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Danio rerio 64084 R-GGA-6806966 https://reactome.org/PathwayBrowser/#/R-GGA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Gallus gallus 64084 R-GGA-6806967 https://reactome.org/PathwayBrowser/#/R-GGA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Gallus gallus 64084 R-HSA-6806966 https://reactome.org/PathwayBrowser/#/R-HSA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX TAS Homo sapiens 64084 R-HSA-6806967 https://reactome.org/PathwayBrowser/#/R-HSA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH TAS Homo sapiens 64084 R-MMU-6806966 https://reactome.org/PathwayBrowser/#/R-MMU-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Mus musculus 64084 R-MMU-6806967 https://reactome.org/PathwayBrowser/#/R-MMU-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Mus musculus 64084 R-PFA-6806966 https://reactome.org/PathwayBrowser/#/R-PFA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Plasmodium falciparum 64084 R-PFA-6806967 https://reactome.org/PathwayBrowser/#/R-PFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Plasmodium falciparum 64084 R-RNO-6806966 https://reactome.org/PathwayBrowser/#/R-RNO-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Rattus norvegicus 64084 R-RNO-6806967 https://reactome.org/PathwayBrowser/#/R-RNO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Rattus norvegicus 64084 R-SCE-6806966 https://reactome.org/PathwayBrowser/#/R-SCE-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Saccharomyces cerevisiae 64084 R-SCE-6806967 https://reactome.org/PathwayBrowser/#/R-SCE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Saccharomyces cerevisiae 64084 R-SPO-6806966 https://reactome.org/PathwayBrowser/#/R-SPO-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Schizosaccharomyces pombe 64084 R-SPO-6806967 https://reactome.org/PathwayBrowser/#/R-SPO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Schizosaccharomyces pombe 64084 R-SSC-6806966 https://reactome.org/PathwayBrowser/#/R-SSC-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Sus scrofa 64084 R-SSC-6806967 https://reactome.org/PathwayBrowser/#/R-SSC-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Sus scrofa 64084 R-XTR-6806967 https://reactome.org/PathwayBrowser/#/R-XTR-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Xenopus tropicalis 64085 R-BTA-6806966 https://reactome.org/PathwayBrowser/#/R-BTA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Bos taurus 64085 R-CEL-6806966 https://reactome.org/PathwayBrowser/#/R-CEL-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Caenorhabditis elegans 64085 R-CFA-6806966 https://reactome.org/PathwayBrowser/#/R-CFA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Canis familiaris 64085 R-DDI-6806966 https://reactome.org/PathwayBrowser/#/R-DDI-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Dictyostelium discoideum 64085 R-DME-6806966 https://reactome.org/PathwayBrowser/#/R-DME-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Drosophila melanogaster 64085 R-DRE-6806966 https://reactome.org/PathwayBrowser/#/R-DRE-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Danio rerio 64085 R-GGA-6806966 https://reactome.org/PathwayBrowser/#/R-GGA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Gallus gallus 64085 R-HSA-6806966 https://reactome.org/PathwayBrowser/#/R-HSA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX TAS Homo sapiens 64085 R-MMU-6806966 https://reactome.org/PathwayBrowser/#/R-MMU-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Mus musculus 64085 R-PFA-6806966 https://reactome.org/PathwayBrowser/#/R-PFA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Plasmodium falciparum 64085 R-RNO-6806966 https://reactome.org/PathwayBrowser/#/R-RNO-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Rattus norvegicus 64085 R-SCE-6806966 https://reactome.org/PathwayBrowser/#/R-SCE-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Saccharomyces cerevisiae 64085 R-SPO-6806966 https://reactome.org/PathwayBrowser/#/R-SPO-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Schizosaccharomyces pombe 64085 R-SSC-6806966 https://reactome.org/PathwayBrowser/#/R-SSC-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Sus scrofa 641 R-BTA-434650 https://reactome.org/PathwayBrowser/#/R-BTA-434650 MATEs mediate extrusion of xenobiotics IEA Bos taurus 641 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 641 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 641 R-BTA-549304 https://reactome.org/PathwayBrowser/#/R-BTA-549304 OCT3 mediates renal clearance of organic cations IEA Bos taurus 641 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 641 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 641 R-BTA-561072 https://reactome.org/PathwayBrowser/#/R-BTA-561072 OCT3 mediates renal uptake of organic cations IEA Bos taurus 641 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 641 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 641 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans 641 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 641 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 641 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans 641 R-CFA-434650 https://reactome.org/PathwayBrowser/#/R-CFA-434650 MATEs mediate extrusion of xenobiotics IEA Canis familiaris 641 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 641 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 641 R-CFA-549304 https://reactome.org/PathwayBrowser/#/R-CFA-549304 OCT3 mediates renal clearance of organic cations IEA Canis familiaris 641 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 641 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 641 R-CFA-561072 https://reactome.org/PathwayBrowser/#/R-CFA-561072 OCT3 mediates renal uptake of organic cations IEA Canis familiaris 641 R-DDI-434650 https://reactome.org/PathwayBrowser/#/R-DDI-434650 MATEs mediate extrusion of xenobiotics IEA Dictyostelium discoideum 641 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 641 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 641 R-DME-549304 https://reactome.org/PathwayBrowser/#/R-DME-549304 OCT3 mediates renal clearance of organic cations IEA Drosophila melanogaster 641 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 641 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 641 R-DME-561072 https://reactome.org/PathwayBrowser/#/R-DME-561072 OCT3 mediates renal uptake of organic cations IEA Drosophila melanogaster 641 R-DRE-434650 https://reactome.org/PathwayBrowser/#/R-DRE-434650 MATEs mediate extrusion of xenobiotics IEA Danio rerio 641 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 641 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 641 R-DRE-549304 https://reactome.org/PathwayBrowser/#/R-DRE-549304 OCT3 mediates renal clearance of organic cations IEA Danio rerio 641 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 641 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 641 R-DRE-561072 https://reactome.org/PathwayBrowser/#/R-DRE-561072 OCT3 mediates renal uptake of organic cations IEA Danio rerio 641 R-GGA-434650 https://reactome.org/PathwayBrowser/#/R-GGA-434650 MATEs mediate extrusion of xenobiotics IEA Gallus gallus 641 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 641 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 641 R-GGA-549304 https://reactome.org/PathwayBrowser/#/R-GGA-549304 OCT3 mediates renal clearance of organic cations IEA Gallus gallus 641 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 641 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 641 R-GGA-561072 https://reactome.org/PathwayBrowser/#/R-GGA-561072 OCT3 mediates renal uptake of organic cations IEA Gallus gallus 641 R-HSA-434650 https://reactome.org/PathwayBrowser/#/R-HSA-434650 MATEs mediate extrusion of xenobiotics TAS Homo sapiens 641 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 641 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 641 R-HSA-549304 https://reactome.org/PathwayBrowser/#/R-HSA-549304 OCT3 mediates renal clearance of organic cations TAS Homo sapiens 641 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 641 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 641 R-HSA-561072 https://reactome.org/PathwayBrowser/#/R-HSA-561072 OCT3 mediates renal uptake of organic cations TAS Homo sapiens 641 R-MMU-434650 https://reactome.org/PathwayBrowser/#/R-MMU-434650 MATEs mediate extrusion of xenobiotics IEA Mus musculus 641 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 641 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 641 R-MMU-549304 https://reactome.org/PathwayBrowser/#/R-MMU-549304 OCT3 mediates renal clearance of organic cations IEA Mus musculus 641 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 641 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 641 R-MMU-561072 https://reactome.org/PathwayBrowser/#/R-MMU-561072 OCT3 mediates renal uptake of organic cations IEA Mus musculus 641 R-PFA-434650 https://reactome.org/PathwayBrowser/#/R-PFA-434650 MATEs mediate extrusion of xenobiotics IEA Plasmodium falciparum 641 R-RNO-434650 https://reactome.org/PathwayBrowser/#/R-RNO-434650 MATEs mediate extrusion of xenobiotics IEA Rattus norvegicus 641 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 641 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 641 R-RNO-549304 https://reactome.org/PathwayBrowser/#/R-RNO-549304 OCT3 mediates renal clearance of organic cations IEA Rattus norvegicus 641 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 641 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 641 R-RNO-561072 https://reactome.org/PathwayBrowser/#/R-RNO-561072 OCT3 mediates renal uptake of organic cations IEA Rattus norvegicus 641 R-SCE-434650 https://reactome.org/PathwayBrowser/#/R-SCE-434650 MATEs mediate extrusion of xenobiotics IEA Saccharomyces cerevisiae 641 R-SPO-434650 https://reactome.org/PathwayBrowser/#/R-SPO-434650 MATEs mediate extrusion of xenobiotics IEA Schizosaccharomyces pombe 641 R-SSC-434650 https://reactome.org/PathwayBrowser/#/R-SSC-434650 MATEs mediate extrusion of xenobiotics IEA Sus scrofa 641 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 641 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 641 R-SSC-549304 https://reactome.org/PathwayBrowser/#/R-SSC-549304 OCT3 mediates renal clearance of organic cations IEA Sus scrofa 641 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 641 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 641 R-SSC-561072 https://reactome.org/PathwayBrowser/#/R-SSC-561072 OCT3 mediates renal uptake of organic cations IEA Sus scrofa 641 R-XTR-434650 https://reactome.org/PathwayBrowser/#/R-XTR-434650 MATEs mediate extrusion of xenobiotics IEA Xenopus tropicalis 641 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 641 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 641 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 641 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 64124 R-BTA-428262 https://reactome.org/PathwayBrowser/#/R-BTA-428262 ACER3 hydrolyzes phytoceramide IEA Bos taurus 64124 R-CFA-428262 https://reactome.org/PathwayBrowser/#/R-CFA-428262 ACER3 hydrolyzes phytoceramide IEA Canis familiaris 64124 R-DDI-428262 https://reactome.org/PathwayBrowser/#/R-DDI-428262 ACER3 hydrolyzes phytoceramide IEA Dictyostelium discoideum 64124 R-GGA-428262 https://reactome.org/PathwayBrowser/#/R-GGA-428262 ACER3 hydrolyzes phytoceramide IEA Gallus gallus 64124 R-GGA-433578 https://reactome.org/PathwayBrowser/#/R-GGA-433578 phytoceramide + H2O => stearate + phytosphingosine IEA Gallus gallus 64124 R-HSA-428262 https://reactome.org/PathwayBrowser/#/R-HSA-428262 ACER3 hydrolyzes phytoceramide TAS Homo sapiens 64124 R-MMU-428262 https://reactome.org/PathwayBrowser/#/R-MMU-428262 ACER3 hydrolyzes phytoceramide IEA Mus musculus 64124 R-RNO-428262 https://reactome.org/PathwayBrowser/#/R-RNO-428262 ACER3 hydrolyzes phytoceramide IEA Rattus norvegicus 64124 R-SCE-428262 https://reactome.org/PathwayBrowser/#/R-SCE-428262 ACER3 hydrolyzes phytoceramide IEA Saccharomyces cerevisiae 64124 R-SSC-428262 https://reactome.org/PathwayBrowser/#/R-SSC-428262 ACER3 hydrolyzes phytoceramide IEA Sus scrofa 64124 R-XTR-428262 https://reactome.org/PathwayBrowser/#/R-XTR-428262 ACER3 hydrolyzes phytoceramide IEA Xenopus tropicalis 64153 R-HSA-1218824 https://reactome.org/PathwayBrowser/#/R-HSA-1218824 HSP90 is inactivated by binding to benzaquinoid ansamycins TAS Homo sapiens 64180 R-BTA-2162188 https://reactome.org/PathwayBrowser/#/R-BTA-2162188 COQ5 methylates MDMQ10H2 IEA Bos taurus 64180 R-CEL-2162188 https://reactome.org/PathwayBrowser/#/R-CEL-2162188 COQ5 methylates MDMQ10H2 IEA Caenorhabditis elegans 64180 R-CFA-2162188 https://reactome.org/PathwayBrowser/#/R-CFA-2162188 COQ5 methylates MDMQ10H2 IEA Canis familiaris 64180 R-DDI-2162188 https://reactome.org/PathwayBrowser/#/R-DDI-2162188 COQ5 methylates MDMQ10H2 IEA Dictyostelium discoideum 64180 R-DME-2162188 https://reactome.org/PathwayBrowser/#/R-DME-2162188 COQ5 methylates MDMQ10H2 IEA Drosophila melanogaster 64180 R-DRE-2162188 https://reactome.org/PathwayBrowser/#/R-DRE-2162188 COQ5 methylates MDMQ10H2 IEA Danio rerio 64180 R-GGA-2162188 https://reactome.org/PathwayBrowser/#/R-GGA-2162188 COQ5 methylates MDMQ10H2 IEA Gallus gallus 64180 R-HSA-2162188 https://reactome.org/PathwayBrowser/#/R-HSA-2162188 COQ5 methylates MDMQ10H2 TAS Homo sapiens 64180 R-HSA-2162191 https://reactome.org/PathwayBrowser/#/R-HSA-2162191 Unknown enzyme hydroxylates DMPhOH IEA Homo sapiens 64180 R-MMU-2162188 https://reactome.org/PathwayBrowser/#/R-MMU-2162188 COQ5 methylates MDMQ10H2 IEA Mus musculus 64180 R-RNO-2162188 https://reactome.org/PathwayBrowser/#/R-RNO-2162188 COQ5 methylates MDMQ10H2 IEA Rattus norvegicus 64180 R-SCE-2162188 https://reactome.org/PathwayBrowser/#/R-SCE-2162188 COQ5 methylates MDMQ10H2 IEA Saccharomyces cerevisiae 64180 R-SPO-2162188 https://reactome.org/PathwayBrowser/#/R-SPO-2162188 COQ5 methylates MDMQ10H2 IEA Schizosaccharomyces pombe 64180 R-SSC-2162188 https://reactome.org/PathwayBrowser/#/R-SSC-2162188 COQ5 methylates MDMQ10H2 IEA Sus scrofa 64180 R-XTR-2162188 https://reactome.org/PathwayBrowser/#/R-XTR-2162188 COQ5 methylates MDMQ10H2 IEA Xenopus tropicalis 64181 R-BTA-2162188 https://reactome.org/PathwayBrowser/#/R-BTA-2162188 COQ5 methylates MDMQ10H2 IEA Bos taurus 64181 R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 64181 R-CEL-2162188 https://reactome.org/PathwayBrowser/#/R-CEL-2162188 COQ5 methylates MDMQ10H2 IEA Caenorhabditis elegans 64181 R-CFA-2162188 https://reactome.org/PathwayBrowser/#/R-CFA-2162188 COQ5 methylates MDMQ10H2 IEA Canis familiaris 64181 R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 64181 R-DDI-2162188 https://reactome.org/PathwayBrowser/#/R-DDI-2162188 COQ5 methylates MDMQ10H2 IEA Dictyostelium discoideum 64181 R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 64181 R-DME-2162188 https://reactome.org/PathwayBrowser/#/R-DME-2162188 COQ5 methylates MDMQ10H2 IEA Drosophila melanogaster 64181 R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 64181 R-DRE-2162188 https://reactome.org/PathwayBrowser/#/R-DRE-2162188 COQ5 methylates MDMQ10H2 IEA Danio rerio 64181 R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 64181 R-GGA-2162188 https://reactome.org/PathwayBrowser/#/R-GGA-2162188 COQ5 methylates MDMQ10H2 IEA Gallus gallus 64181 R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 64181 R-HSA-2162188 https://reactome.org/PathwayBrowser/#/R-HSA-2162188 COQ5 methylates MDMQ10H2 TAS Homo sapiens 64181 R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 64181 R-MMU-2162188 https://reactome.org/PathwayBrowser/#/R-MMU-2162188 COQ5 methylates MDMQ10H2 IEA Mus musculus 64181 R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 64181 R-RNO-2162188 https://reactome.org/PathwayBrowser/#/R-RNO-2162188 COQ5 methylates MDMQ10H2 IEA Rattus norvegicus 64181 R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 64181 R-SCE-2162188 https://reactome.org/PathwayBrowser/#/R-SCE-2162188 COQ5 methylates MDMQ10H2 IEA Saccharomyces cerevisiae 64181 R-SCE-2162194 https://reactome.org/PathwayBrowser/#/R-SCE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Saccharomyces cerevisiae 64181 R-SPO-2162188 https://reactome.org/PathwayBrowser/#/R-SPO-2162188 COQ5 methylates MDMQ10H2 IEA Schizosaccharomyces pombe 64181 R-SPO-2162194 https://reactome.org/PathwayBrowser/#/R-SPO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Schizosaccharomyces pombe 64181 R-SSC-2162188 https://reactome.org/PathwayBrowser/#/R-SSC-2162188 COQ5 methylates MDMQ10H2 IEA Sus scrofa 64181 R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa 64181 R-XTR-2162188 https://reactome.org/PathwayBrowser/#/R-XTR-2162188 COQ5 methylates MDMQ10H2 IEA Xenopus tropicalis 64181 R-XTR-2162194 https://reactome.org/PathwayBrowser/#/R-XTR-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Xenopus tropicalis 64182 R-BTA-2162186 https://reactome.org/PathwayBrowser/#/R-BTA-2162186 COQ3 methylates DeMQ10H2 IEA Bos taurus 64182 R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 64182 R-CEL-2162186 https://reactome.org/PathwayBrowser/#/R-CEL-2162186 COQ3 methylates DeMQ10H2 IEA Caenorhabditis elegans 64182 R-CFA-2162186 https://reactome.org/PathwayBrowser/#/R-CFA-2162186 COQ3 methylates DeMQ10H2 IEA Canis familiaris 64182 R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 64182 R-DDI-2162186 https://reactome.org/PathwayBrowser/#/R-DDI-2162186 COQ3 methylates DeMQ10H2 IEA Dictyostelium discoideum 64182 R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 64182 R-DME-2162186 https://reactome.org/PathwayBrowser/#/R-DME-2162186 COQ3 methylates DeMQ10H2 IEA Drosophila melanogaster 64182 R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 64182 R-DRE-2162186 https://reactome.org/PathwayBrowser/#/R-DRE-2162186 COQ3 methylates DeMQ10H2 IEA Danio rerio 64182 R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 64182 R-GGA-2162186 https://reactome.org/PathwayBrowser/#/R-GGA-2162186 COQ3 methylates DeMQ10H2 IEA Gallus gallus 64182 R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 64182 R-HSA-2162186 https://reactome.org/PathwayBrowser/#/R-HSA-2162186 COQ3 methylates DeMQ10H2 TAS Homo sapiens 64182 R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 64182 R-MMU-2162186 https://reactome.org/PathwayBrowser/#/R-MMU-2162186 COQ3 methylates DeMQ10H2 IEA Mus musculus 64182 R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 64182 R-RNO-2162186 https://reactome.org/PathwayBrowser/#/R-RNO-2162186 COQ3 methylates DeMQ10H2 IEA Rattus norvegicus 64182 R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 64182 R-SCE-2162186 https://reactome.org/PathwayBrowser/#/R-SCE-2162186 COQ3 methylates DeMQ10H2 IEA Saccharomyces cerevisiae 64182 R-SCE-2162194 https://reactome.org/PathwayBrowser/#/R-SCE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Saccharomyces cerevisiae 64182 R-SPO-2162186 https://reactome.org/PathwayBrowser/#/R-SPO-2162186 COQ3 methylates DeMQ10H2 IEA Schizosaccharomyces pombe 64182 R-SPO-2162194 https://reactome.org/PathwayBrowser/#/R-SPO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Schizosaccharomyces pombe 64182 R-SSC-2162186 https://reactome.org/PathwayBrowser/#/R-SSC-2162186 COQ3 methylates DeMQ10H2 IEA Sus scrofa 64182 R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa 64182 R-XTR-2162186 https://reactome.org/PathwayBrowser/#/R-XTR-2162186 COQ3 methylates DeMQ10H2 IEA Xenopus tropicalis 64182 R-XTR-2162194 https://reactome.org/PathwayBrowser/#/R-XTR-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Xenopus tropicalis 64183 R-BTA-2162186 https://reactome.org/PathwayBrowser/#/R-BTA-2162186 COQ3 methylates DeMQ10H2 IEA Bos taurus 64183 R-BTA-70994 https://reactome.org/PathwayBrowser/#/R-BTA-70994 SDH complex dehydrogenates succinate IEA Bos taurus 64183 R-CEL-2162186 https://reactome.org/PathwayBrowser/#/R-CEL-2162186 COQ3 methylates DeMQ10H2 IEA Caenorhabditis elegans 64183 R-CEL-70994 https://reactome.org/PathwayBrowser/#/R-CEL-70994 SDH complex dehydrogenates succinate IEA Caenorhabditis elegans 64183 R-CFA-2162186 https://reactome.org/PathwayBrowser/#/R-CFA-2162186 COQ3 methylates DeMQ10H2 IEA Canis familiaris 64183 R-CFA-70994 https://reactome.org/PathwayBrowser/#/R-CFA-70994 SDH complex dehydrogenates succinate IEA Canis familiaris 64183 R-DDI-2162186 https://reactome.org/PathwayBrowser/#/R-DDI-2162186 COQ3 methylates DeMQ10H2 IEA Dictyostelium discoideum 64183 R-DDI-70994 https://reactome.org/PathwayBrowser/#/R-DDI-70994 SDH complex dehydrogenates succinate IEA Dictyostelium discoideum 64183 R-DME-2162186 https://reactome.org/PathwayBrowser/#/R-DME-2162186 COQ3 methylates DeMQ10H2 IEA Drosophila melanogaster 64183 R-DME-70994 https://reactome.org/PathwayBrowser/#/R-DME-70994 SDH complex dehydrogenates succinate IEA Drosophila melanogaster 64183 R-DRE-2162186 https://reactome.org/PathwayBrowser/#/R-DRE-2162186 COQ3 methylates DeMQ10H2 IEA Danio rerio 64183 R-DRE-70994 https://reactome.org/PathwayBrowser/#/R-DRE-70994 SDH complex dehydrogenates succinate IEA Danio rerio 64183 R-GGA-2162186 https://reactome.org/PathwayBrowser/#/R-GGA-2162186 COQ3 methylates DeMQ10H2 IEA Gallus gallus 64183 R-GGA-70994 https://reactome.org/PathwayBrowser/#/R-GGA-70994 SDH complex dehydrogenates succinate IEA Gallus gallus 64183 R-HSA-2162186 https://reactome.org/PathwayBrowser/#/R-HSA-2162186 COQ3 methylates DeMQ10H2 TAS Homo sapiens 64183 R-HSA-70994 https://reactome.org/PathwayBrowser/#/R-HSA-70994 SDH complex dehydrogenates succinate TAS Homo sapiens 64183 R-MMU-2162186 https://reactome.org/PathwayBrowser/#/R-MMU-2162186 COQ3 methylates DeMQ10H2 IEA Mus musculus 64183 R-MMU-70994 https://reactome.org/PathwayBrowser/#/R-MMU-70994 SDH complex dehydrogenates succinate IEA Mus musculus 64183 R-RNO-2162186 https://reactome.org/PathwayBrowser/#/R-RNO-2162186 COQ3 methylates DeMQ10H2 IEA Rattus norvegicus 64183 R-RNO-70994 https://reactome.org/PathwayBrowser/#/R-RNO-70994 SDH complex dehydrogenates succinate IEA Rattus norvegicus 64183 R-SCE-2162186 https://reactome.org/PathwayBrowser/#/R-SCE-2162186 COQ3 methylates DeMQ10H2 IEA Saccharomyces cerevisiae 64183 R-SCE-70994 https://reactome.org/PathwayBrowser/#/R-SCE-70994 SDH complex dehydrogenates succinate IEA Saccharomyces cerevisiae 64183 R-SPO-2162186 https://reactome.org/PathwayBrowser/#/R-SPO-2162186 COQ3 methylates DeMQ10H2 IEA Schizosaccharomyces pombe 64183 R-SPO-70994 https://reactome.org/PathwayBrowser/#/R-SPO-70994 SDH complex dehydrogenates succinate IEA Schizosaccharomyces pombe 64183 R-SSC-2162186 https://reactome.org/PathwayBrowser/#/R-SSC-2162186 COQ3 methylates DeMQ10H2 IEA Sus scrofa 64183 R-SSC-70994 https://reactome.org/PathwayBrowser/#/R-SSC-70994 SDH complex dehydrogenates succinate IEA Sus scrofa 64183 R-XTR-2162186 https://reactome.org/PathwayBrowser/#/R-XTR-2162186 COQ3 methylates DeMQ10H2 IEA Xenopus tropicalis 64183 R-XTR-70994 https://reactome.org/PathwayBrowser/#/R-XTR-70994 SDH complex dehydrogenates succinate IEA Xenopus tropicalis 64189 R-HSA-2162099 https://reactome.org/PathwayBrowser/#/R-HSA-2162099 abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP TAS Homo sapiens 64192 R-BTA-2162078 https://reactome.org/PathwayBrowser/#/R-BTA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Bos taurus 64192 R-CEL-2162078 https://reactome.org/PathwayBrowser/#/R-CEL-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Caenorhabditis elegans 64192 R-CFA-2162078 https://reactome.org/PathwayBrowser/#/R-CFA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Canis familiaris 64192 R-DDI-2162078 https://reactome.org/PathwayBrowser/#/R-DDI-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Dictyostelium discoideum 64192 R-DME-2162078 https://reactome.org/PathwayBrowser/#/R-DME-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Drosophila melanogaster 64192 R-DRE-2162078 https://reactome.org/PathwayBrowser/#/R-DRE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Danio rerio 64192 R-GGA-2162078 https://reactome.org/PathwayBrowser/#/R-GGA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Gallus gallus 64192 R-HSA-2162078 https://reactome.org/PathwayBrowser/#/R-HSA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ TAS Homo sapiens 64192 R-MMU-2162078 https://reactome.org/PathwayBrowser/#/R-MMU-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Mus musculus 64192 R-RNO-2162078 https://reactome.org/PathwayBrowser/#/R-RNO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Rattus norvegicus 64192 R-SCE-2162078 https://reactome.org/PathwayBrowser/#/R-SCE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Saccharomyces cerevisiae 64192 R-SPO-2162078 https://reactome.org/PathwayBrowser/#/R-SPO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Schizosaccharomyces pombe 64192 R-SSC-2162078 https://reactome.org/PathwayBrowser/#/R-SSC-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Sus scrofa 64192 R-XTR-2162078 https://reactome.org/PathwayBrowser/#/R-XTR-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Xenopus tropicalis 64294 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 64294 R-BTA-2197646 https://reactome.org/PathwayBrowser/#/R-BTA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Bos taurus 64294 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 64294 R-BTA-2512800 https://reactome.org/PathwayBrowser/#/R-BTA-2512800 SCARB1:ligand is endocytosed IEA Bos taurus 64294 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 64294 R-BTA-8869667 https://reactome.org/PathwayBrowser/#/R-BTA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Bos taurus 64294 R-CFA-2197646 https://reactome.org/PathwayBrowser/#/R-CFA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Canis familiaris 64294 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 64294 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 64294 R-CFA-2512800 https://reactome.org/PathwayBrowser/#/R-CFA-2512800 SCARB1:ligand is endocytosed IEA Canis familiaris 64294 R-GGA-2197646 https://reactome.org/PathwayBrowser/#/R-GGA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Gallus gallus 64294 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 64294 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 64294 R-GGA-2512800 https://reactome.org/PathwayBrowser/#/R-GGA-2512800 SCARB1:ligand is endocytosed IEA Gallus gallus 64294 R-GGA-8869667 https://reactome.org/PathwayBrowser/#/R-GGA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Gallus gallus 64294 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 64294 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 64294 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 64294 R-HSA-2197645 https://reactome.org/PathwayBrowser/#/R-HSA-2197645 SCARF1 (SREC-I) binds ligands IEA Homo sapiens 64294 R-HSA-2197646 https://reactome.org/PathwayBrowser/#/R-HSA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands TAS Homo sapiens 64294 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 64294 R-HSA-2247514 https://reactome.org/PathwayBrowser/#/R-HSA-2247514 SCARF1:ligand is endocytosed TAS Homo sapiens 64294 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 64294 R-HSA-2512800 https://reactome.org/PathwayBrowser/#/R-HSA-2512800 SCARB1:ligand is endocytosed TAS Homo sapiens 64294 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 64294 R-HSA-8869667 https://reactome.org/PathwayBrowser/#/R-HSA-8869667 oxLDL:CD36 binds TLR4:TLR6 TAS Homo sapiens 64294 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 64294 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 64294 R-MMU-2197646 https://reactome.org/PathwayBrowser/#/R-MMU-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Mus musculus 64294 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 64294 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 64294 R-MMU-2512800 https://reactome.org/PathwayBrowser/#/R-MMU-2512800 SCARB1:ligand is endocytosed IEA Mus musculus 64294 R-MMU-8869667 https://reactome.org/PathwayBrowser/#/R-MMU-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Mus musculus 64294 R-RNO-2197646 https://reactome.org/PathwayBrowser/#/R-RNO-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Rattus norvegicus 64294 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 64294 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 64294 R-RNO-2512800 https://reactome.org/PathwayBrowser/#/R-RNO-2512800 SCARB1:ligand is endocytosed IEA Rattus norvegicus 64294 R-RNO-8869667 https://reactome.org/PathwayBrowser/#/R-RNO-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Rattus norvegicus 64294 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa 64294 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 64294 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 64294 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa 64294 R-SSC-8869667 https://reactome.org/PathwayBrowser/#/R-SSC-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Sus scrofa 64299 R-HSA-6782443 https://reactome.org/PathwayBrowser/#/R-HSA-6782443 QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr) TAS Homo sapiens 64315 R-HSA-6782893 https://reactome.org/PathwayBrowser/#/R-HSA-6782893 TRMT12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 64315 R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 64315 R-SCE-6783410 https://reactome.org/PathwayBrowser/#/R-SCE-6783410 TRM12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 64315 R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 64317 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 64317 R-BTA-9611751 https://reactome.org/PathwayBrowser/#/R-BTA-9611751 β1,2-agonists bind ADRB1,2 IEA Bos taurus 64317 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 64317 R-CFA-9611751 https://reactome.org/PathwayBrowser/#/R-CFA-9611751 β1,2-agonists bind ADRB1,2 IEA Canis familiaris 64317 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 64317 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 64317 R-DME-9611751 https://reactome.org/PathwayBrowser/#/R-DME-9611751 β1,2-agonists bind ADRB1,2 IEA Drosophila melanogaster 64317 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 64317 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 64317 R-DRE-9611751 https://reactome.org/PathwayBrowser/#/R-DRE-9611751 β1,2-agonists bind ADRB1,2 IEA Danio rerio 64317 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 64317 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 64317 R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus 64317 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 64317 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 64317 R-HSA-9611751 https://reactome.org/PathwayBrowser/#/R-HSA-9611751 β1,2-agonists bind ADRB1,2 TAS Homo sapiens 64317 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 64317 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 64317 R-MMU-9611751 https://reactome.org/PathwayBrowser/#/R-MMU-9611751 β1,2-agonists bind ADRB1,2 IEA Mus musculus 64317 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 64317 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 64317 R-RNO-9611751 https://reactome.org/PathwayBrowser/#/R-RNO-9611751 β1,2-agonists bind ADRB1,2 IEA Rattus norvegicus 64317 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 64317 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 64317 R-SSC-9611751 https://reactome.org/PathwayBrowser/#/R-SSC-9611751 β1,2-agonists bind ADRB1,2 IEA Sus scrofa 64317 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 64317 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 64317 R-XTR-9611751 https://reactome.org/PathwayBrowser/#/R-XTR-9611751 β1,2-agonists bind ADRB1,2 IEA Xenopus tropicalis 64317 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 6438 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 6438 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 6438 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 6438 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 6438 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 6438 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 6438 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 6438 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 6438 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 6438 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 6438 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 6438 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 6438 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 6438 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 6438 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 6438 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 6438 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 6438 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 6438 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 6438 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 6438 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 6438 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 6438 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 6438 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 6438 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 6438 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 6438 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 6438 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 6438 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 6438 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 6438 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 6438 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 6438 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 6438 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 6438 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 6438 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 6438 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 64483 R-BTA-5694485 https://reactome.org/PathwayBrowser/#/R-BTA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Bos taurus 64483 R-CEL-5694485 https://reactome.org/PathwayBrowser/#/R-CEL-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Caenorhabditis elegans 64483 R-CFA-5694485 https://reactome.org/PathwayBrowser/#/R-CFA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Canis familiaris 64483 R-DDI-5694485 https://reactome.org/PathwayBrowser/#/R-DDI-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Dictyostelium discoideum 64483 R-DME-5694485 https://reactome.org/PathwayBrowser/#/R-DME-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Drosophila melanogaster 64483 R-DRE-5694485 https://reactome.org/PathwayBrowser/#/R-DRE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Danio rerio 64483 R-GGA-5694485 https://reactome.org/PathwayBrowser/#/R-GGA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Gallus gallus 64483 R-HSA-5694485 https://reactome.org/PathwayBrowser/#/R-HSA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC TAS Homo sapiens 64483 R-MMU-5694485 https://reactome.org/PathwayBrowser/#/R-MMU-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Mus musculus 64483 R-RNO-5694485 https://reactome.org/PathwayBrowser/#/R-RNO-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Rattus norvegicus 64483 R-SCE-5694485 https://reactome.org/PathwayBrowser/#/R-SCE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Saccharomyces cerevisiae 64483 R-SSC-5694485 https://reactome.org/PathwayBrowser/#/R-SSC-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Sus scrofa 64483 R-XTR-5694485 https://reactome.org/PathwayBrowser/#/R-XTR-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Xenopus tropicalis 64567 R-BTA-8865637 https://reactome.org/PathwayBrowser/#/R-BTA-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Bos taurus 64567 R-CFA-8865637 https://reactome.org/PathwayBrowser/#/R-CFA-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Canis familiaris 64567 R-DDI-8865637 https://reactome.org/PathwayBrowser/#/R-DDI-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Dictyostelium discoideum 64567 R-DRE-8865637 https://reactome.org/PathwayBrowser/#/R-DRE-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Danio rerio 64567 R-GGA-8865637 https://reactome.org/PathwayBrowser/#/R-GGA-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Gallus gallus 64567 R-HSA-8865637 https://reactome.org/PathwayBrowser/#/R-HSA-8865637 MFSD2A transports LPC from extracellular region to plasma membrane TAS Homo sapiens 64567 R-MMU-8865637 https://reactome.org/PathwayBrowser/#/R-MMU-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Mus musculus 64567 R-PFA-8865637 https://reactome.org/PathwayBrowser/#/R-PFA-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Plasmodium falciparum 64567 R-RNO-8865637 https://reactome.org/PathwayBrowser/#/R-RNO-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Rattus norvegicus 64567 R-SSC-8865637 https://reactome.org/PathwayBrowser/#/R-SSC-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Sus scrofa 64567 R-XTR-8865637 https://reactome.org/PathwayBrowser/#/R-XTR-8865637 MFSD2A transports LPC from extracellular region to plasma membrane IEA Xenopus tropicalis 64583 R-BTA-429786 https://reactome.org/PathwayBrowser/#/R-BTA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Bos taurus 64583 R-BTA-429798 https://reactome.org/PathwayBrowser/#/R-BTA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Bos taurus 64583 R-CEL-429786 https://reactome.org/PathwayBrowser/#/R-CEL-429786 SGMS2 transfers phosphocholine onto ceramide IEA Caenorhabditis elegans 64583 R-CEL-429798 https://reactome.org/PathwayBrowser/#/R-CEL-429798 SGMS1 transfers phosphocholine onto ceramide IEA Caenorhabditis elegans 64583 R-CFA-429786 https://reactome.org/PathwayBrowser/#/R-CFA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Canis familiaris 64583 R-CFA-429798 https://reactome.org/PathwayBrowser/#/R-CFA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Canis familiaris 64583 R-DRE-429786 https://reactome.org/PathwayBrowser/#/R-DRE-429786 SGMS2 transfers phosphocholine onto ceramide IEA Danio rerio 64583 R-DRE-429798 https://reactome.org/PathwayBrowser/#/R-DRE-429798 SGMS1 transfers phosphocholine onto ceramide IEA Danio rerio 64583 R-GGA-429786 https://reactome.org/PathwayBrowser/#/R-GGA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Gallus gallus 64583 R-GGA-429798 https://reactome.org/PathwayBrowser/#/R-GGA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Gallus gallus 64583 R-HSA-429786 https://reactome.org/PathwayBrowser/#/R-HSA-429786 SGMS2 transfers phosphocholine onto ceramide TAS Homo sapiens 64583 R-HSA-429798 https://reactome.org/PathwayBrowser/#/R-HSA-429798 SGMS1 transfers phosphocholine onto ceramide TAS Homo sapiens 64583 R-MMU-429786 https://reactome.org/PathwayBrowser/#/R-MMU-429786 SGMS2 transfers phosphocholine onto ceramide IEA Mus musculus 64583 R-MMU-429798 https://reactome.org/PathwayBrowser/#/R-MMU-429798 SGMS1 transfers phosphocholine onto ceramide IEA Mus musculus 64583 R-PFA-429786 https://reactome.org/PathwayBrowser/#/R-PFA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Plasmodium falciparum 64583 R-PFA-429798 https://reactome.org/PathwayBrowser/#/R-PFA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Plasmodium falciparum 64583 R-RNO-429786 https://reactome.org/PathwayBrowser/#/R-RNO-429786 SGMS2 transfers phosphocholine onto ceramide IEA Rattus norvegicus 64583 R-RNO-429798 https://reactome.org/PathwayBrowser/#/R-RNO-429798 SGMS1 transfers phosphocholine onto ceramide IEA Rattus norvegicus 64583 R-SSC-429786 https://reactome.org/PathwayBrowser/#/R-SSC-429786 SGMS2 transfers phosphocholine onto ceramide IEA Sus scrofa 64583 R-SSC-429798 https://reactome.org/PathwayBrowser/#/R-SSC-429798 SGMS1 transfers phosphocholine onto ceramide IEA Sus scrofa 64583 R-XTR-429786 https://reactome.org/PathwayBrowser/#/R-XTR-429786 SGMS2 transfers phosphocholine onto ceramide IEA Xenopus tropicalis 64583 R-XTR-429798 https://reactome.org/PathwayBrowser/#/R-XTR-429798 SGMS1 transfers phosphocholine onto ceramide IEA Xenopus tropicalis 64606 R-BTA-70971 https://reactome.org/PathwayBrowser/#/R-BTA-70971 ACO2 isomerizes citrate IEA Bos taurus 64606 R-BTA-70994 https://reactome.org/PathwayBrowser/#/R-BTA-70994 SDH complex dehydrogenates succinate IEA Bos taurus 64606 R-BTA-9854368 https://reactome.org/PathwayBrowser/#/R-BTA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Bos taurus 64606 R-BTA-9854405 https://reactome.org/PathwayBrowser/#/R-BTA-9854405 Frataxin transfers Fe2+ to ACO2 IEA Bos taurus 64606 R-BTA-9854984 https://reactome.org/PathwayBrowser/#/R-BTA-9854984 Transfer of Fe-S clusters to SDHB IEA Bos taurus 64606 R-BTA-9855212 https://reactome.org/PathwayBrowser/#/R-BTA-9855212 SDHA binds to SDHB IEA Bos taurus 64606 R-BTA-9855252 https://reactome.org/PathwayBrowser/#/R-BTA-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Bos taurus 64606 R-CEL-70971 https://reactome.org/PathwayBrowser/#/R-CEL-70971 ACO2 isomerizes citrate IEA Caenorhabditis elegans 64606 R-CEL-70994 https://reactome.org/PathwayBrowser/#/R-CEL-70994 SDH complex dehydrogenates succinate IEA Caenorhabditis elegans 64606 R-CEL-9854368 https://reactome.org/PathwayBrowser/#/R-CEL-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Caenorhabditis elegans 64606 R-CEL-9854405 https://reactome.org/PathwayBrowser/#/R-CEL-9854405 Frataxin transfers Fe2+ to ACO2 IEA Caenorhabditis elegans 64606 R-CFA-70971 https://reactome.org/PathwayBrowser/#/R-CFA-70971 ACO2 isomerizes citrate IEA Canis familiaris 64606 R-CFA-70994 https://reactome.org/PathwayBrowser/#/R-CFA-70994 SDH complex dehydrogenates succinate IEA Canis familiaris 64606 R-CFA-9854368 https://reactome.org/PathwayBrowser/#/R-CFA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Canis familiaris 64606 R-CFA-9854405 https://reactome.org/PathwayBrowser/#/R-CFA-9854405 Frataxin transfers Fe2+ to ACO2 IEA Canis familiaris 64606 R-DDI-70971 https://reactome.org/PathwayBrowser/#/R-DDI-70971 ACO2 isomerizes citrate IEA Dictyostelium discoideum 64606 R-DDI-70994 https://reactome.org/PathwayBrowser/#/R-DDI-70994 SDH complex dehydrogenates succinate IEA Dictyostelium discoideum 64606 R-DDI-9854368 https://reactome.org/PathwayBrowser/#/R-DDI-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Dictyostelium discoideum 64606 R-DDI-9854405 https://reactome.org/PathwayBrowser/#/R-DDI-9854405 Frataxin transfers Fe2+ to ACO2 IEA Dictyostelium discoideum 64606 R-DME-70971 https://reactome.org/PathwayBrowser/#/R-DME-70971 ACO2 isomerizes citrate IEA Drosophila melanogaster 64606 R-DME-70994 https://reactome.org/PathwayBrowser/#/R-DME-70994 SDH complex dehydrogenates succinate IEA Drosophila melanogaster 64606 R-DME-9854368 https://reactome.org/PathwayBrowser/#/R-DME-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Drosophila melanogaster 64606 R-DME-9854405 https://reactome.org/PathwayBrowser/#/R-DME-9854405 Frataxin transfers Fe2+ to ACO2 IEA Drosophila melanogaster 64606 R-DRE-70971 https://reactome.org/PathwayBrowser/#/R-DRE-70971 ACO2 isomerizes citrate IEA Danio rerio 64606 R-DRE-70994 https://reactome.org/PathwayBrowser/#/R-DRE-70994 SDH complex dehydrogenates succinate IEA Danio rerio 64606 R-DRE-9854368 https://reactome.org/PathwayBrowser/#/R-DRE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Danio rerio 64606 R-DRE-9854405 https://reactome.org/PathwayBrowser/#/R-DRE-9854405 Frataxin transfers Fe2+ to ACO2 IEA Danio rerio 64606 R-GGA-70971 https://reactome.org/PathwayBrowser/#/R-GGA-70971 ACO2 isomerizes citrate IEA Gallus gallus 64606 R-GGA-70994 https://reactome.org/PathwayBrowser/#/R-GGA-70994 SDH complex dehydrogenates succinate IEA Gallus gallus 64606 R-GGA-9854368 https://reactome.org/PathwayBrowser/#/R-GGA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Gallus gallus 64606 R-GGA-9854405 https://reactome.org/PathwayBrowser/#/R-GGA-9854405 Frataxin transfers Fe2+ to ACO2 IEA Gallus gallus 64606 R-HSA-163213 https://reactome.org/PathwayBrowser/#/R-HSA-163213 Transfer of electrons through the succinate dehydrogenase complex IEA Homo sapiens 64606 R-HSA-70971 https://reactome.org/PathwayBrowser/#/R-HSA-70971 ACO2 isomerizes citrate TAS Homo sapiens 64606 R-HSA-70994 https://reactome.org/PathwayBrowser/#/R-HSA-70994 SDH complex dehydrogenates succinate TAS Homo sapiens 64606 R-HSA-9854368 https://reactome.org/PathwayBrowser/#/R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S TAS Homo sapiens 64606 R-HSA-9854405 https://reactome.org/PathwayBrowser/#/R-HSA-9854405 Frataxin transfers Fe2+ to ACO2 TAS Homo sapiens 64606 R-HSA-9854984 https://reactome.org/PathwayBrowser/#/R-HSA-9854984 Transfer of Fe-S clusters to SDHB TAS Homo sapiens 64606 R-HSA-9855212 https://reactome.org/PathwayBrowser/#/R-HSA-9855212 SDHA binds to SDHB TAS Homo sapiens 64606 R-HSA-9855252 https://reactome.org/PathwayBrowser/#/R-HSA-9855252 SDHA:SDHB binds to SDHC:SDHD TAS Homo sapiens 64606 R-MMU-70971 https://reactome.org/PathwayBrowser/#/R-MMU-70971 ACO2 isomerizes citrate IEA Mus musculus 64606 R-MMU-70994 https://reactome.org/PathwayBrowser/#/R-MMU-70994 SDH complex dehydrogenates succinate IEA Mus musculus 64606 R-MMU-9854368 https://reactome.org/PathwayBrowser/#/R-MMU-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Mus musculus 64606 R-MMU-9854405 https://reactome.org/PathwayBrowser/#/R-MMU-9854405 Frataxin transfers Fe2+ to ACO2 IEA Mus musculus 64606 R-MMU-9854984 https://reactome.org/PathwayBrowser/#/R-MMU-9854984 Transfer of Fe-S clusters to SDHB IEA Mus musculus 64606 R-MMU-9855212 https://reactome.org/PathwayBrowser/#/R-MMU-9855212 SDHA binds to SDHB IEA Mus musculus 64606 R-MMU-9855252 https://reactome.org/PathwayBrowser/#/R-MMU-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Mus musculus 64606 R-RNO-70971 https://reactome.org/PathwayBrowser/#/R-RNO-70971 ACO2 isomerizes citrate IEA Rattus norvegicus 64606 R-RNO-70994 https://reactome.org/PathwayBrowser/#/R-RNO-70994 SDH complex dehydrogenates succinate IEA Rattus norvegicus 64606 R-RNO-9854368 https://reactome.org/PathwayBrowser/#/R-RNO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Rattus norvegicus 64606 R-RNO-9854405 https://reactome.org/PathwayBrowser/#/R-RNO-9854405 Frataxin transfers Fe2+ to ACO2 IEA Rattus norvegicus 64606 R-SCE-70971 https://reactome.org/PathwayBrowser/#/R-SCE-70971 ACO2 isomerizes citrate IEA Saccharomyces cerevisiae 64606 R-SCE-70994 https://reactome.org/PathwayBrowser/#/R-SCE-70994 SDH complex dehydrogenates succinate IEA Saccharomyces cerevisiae 64606 R-SCE-9854368 https://reactome.org/PathwayBrowser/#/R-SCE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Saccharomyces cerevisiae 64606 R-SCE-9854405 https://reactome.org/PathwayBrowser/#/R-SCE-9854405 Frataxin transfers Fe2+ to ACO2 IEA Saccharomyces cerevisiae 64606 R-SPO-70971 https://reactome.org/PathwayBrowser/#/R-SPO-70971 ACO2 isomerizes citrate IEA Schizosaccharomyces pombe 64606 R-SPO-70994 https://reactome.org/PathwayBrowser/#/R-SPO-70994 SDH complex dehydrogenates succinate IEA Schizosaccharomyces pombe 64606 R-SPO-9854368 https://reactome.org/PathwayBrowser/#/R-SPO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Schizosaccharomyces pombe 64606 R-SPO-9854405 https://reactome.org/PathwayBrowser/#/R-SPO-9854405 Frataxin transfers Fe2+ to ACO2 IEA Schizosaccharomyces pombe 64606 R-SSC-70971 https://reactome.org/PathwayBrowser/#/R-SSC-70971 ACO2 isomerizes citrate IEA Sus scrofa 64606 R-SSC-70994 https://reactome.org/PathwayBrowser/#/R-SSC-70994 SDH complex dehydrogenates succinate IEA Sus scrofa 64606 R-SSC-9854368 https://reactome.org/PathwayBrowser/#/R-SSC-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Sus scrofa 64606 R-SSC-9854405 https://reactome.org/PathwayBrowser/#/R-SSC-9854405 Frataxin transfers Fe2+ to ACO2 IEA Sus scrofa 64606 R-SSC-9854984 https://reactome.org/PathwayBrowser/#/R-SSC-9854984 Transfer of Fe-S clusters to SDHB IEA Sus scrofa 64606 R-SSC-9855212 https://reactome.org/PathwayBrowser/#/R-SSC-9855212 SDHA binds to SDHB IEA Sus scrofa 64606 R-SSC-9855252 https://reactome.org/PathwayBrowser/#/R-SSC-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Sus scrofa 64606 R-XTR-70971 https://reactome.org/PathwayBrowser/#/R-XTR-70971 ACO2 isomerizes citrate IEA Xenopus tropicalis 64606 R-XTR-70994 https://reactome.org/PathwayBrowser/#/R-XTR-70994 SDH complex dehydrogenates succinate IEA Xenopus tropicalis 64606 R-XTR-9854368 https://reactome.org/PathwayBrowser/#/R-XTR-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Xenopus tropicalis 64606 R-XTR-9855212 https://reactome.org/PathwayBrowser/#/R-XTR-9855212 SDHA binds to SDHB IEA Xenopus tropicalis 64606 R-XTR-9855252 https://reactome.org/PathwayBrowser/#/R-XTR-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Xenopus tropicalis 64607 R-BTA-163217 https://reactome.org/PathwayBrowser/#/R-BTA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Bos taurus 64607 R-BTA-6788556 https://reactome.org/PathwayBrowser/#/R-BTA-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Bos taurus 64607 R-BTA-6799179 https://reactome.org/PathwayBrowser/#/R-BTA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Bos taurus 64607 R-BTA-6799196 https://reactome.org/PathwayBrowser/#/R-BTA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Bos taurus 64607 R-BTA-6800870 https://reactome.org/PathwayBrowser/#/R-BTA-6800870 NDUF subunits bind to form the FP subcomplex IEA Bos taurus 64607 R-BTA-70994 https://reactome.org/PathwayBrowser/#/R-BTA-70994 SDH complex dehydrogenates succinate IEA Bos taurus 64607 R-BTA-9855252 https://reactome.org/PathwayBrowser/#/R-BTA-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Bos taurus 64607 R-CEL-70994 https://reactome.org/PathwayBrowser/#/R-CEL-70994 SDH complex dehydrogenates succinate IEA Caenorhabditis elegans 64607 R-CFA-163217 https://reactome.org/PathwayBrowser/#/R-CFA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Canis familiaris 64607 R-CFA-6788556 https://reactome.org/PathwayBrowser/#/R-CFA-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Canis familiaris 64607 R-CFA-6799179 https://reactome.org/PathwayBrowser/#/R-CFA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Canis familiaris 64607 R-CFA-6799196 https://reactome.org/PathwayBrowser/#/R-CFA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Canis familiaris 64607 R-CFA-70994 https://reactome.org/PathwayBrowser/#/R-CFA-70994 SDH complex dehydrogenates succinate IEA Canis familiaris 64607 R-DDI-6788556 https://reactome.org/PathwayBrowser/#/R-DDI-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Dictyostelium discoideum 64607 R-DDI-70994 https://reactome.org/PathwayBrowser/#/R-DDI-70994 SDH complex dehydrogenates succinate IEA Dictyostelium discoideum 64607 R-DME-163217 https://reactome.org/PathwayBrowser/#/R-DME-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Drosophila melanogaster 64607 R-DME-6788556 https://reactome.org/PathwayBrowser/#/R-DME-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Drosophila melanogaster 64607 R-DME-6799196 https://reactome.org/PathwayBrowser/#/R-DME-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Drosophila melanogaster 64607 R-DME-70994 https://reactome.org/PathwayBrowser/#/R-DME-70994 SDH complex dehydrogenates succinate IEA Drosophila melanogaster 64607 R-DRE-163217 https://reactome.org/PathwayBrowser/#/R-DRE-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Danio rerio 64607 R-DRE-6788556 https://reactome.org/PathwayBrowser/#/R-DRE-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Danio rerio 64607 R-DRE-70994 https://reactome.org/PathwayBrowser/#/R-DRE-70994 SDH complex dehydrogenates succinate IEA Danio rerio 64607 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Gallus gallus 64607 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus 64607 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus 64607 R-GGA-70994 https://reactome.org/PathwayBrowser/#/R-GGA-70994 SDH complex dehydrogenates succinate IEA Gallus gallus 64607 R-HSA-163213 https://reactome.org/PathwayBrowser/#/R-HSA-163213 Transfer of electrons through the succinate dehydrogenase complex IEA Homo sapiens 64607 R-HSA-163217 https://reactome.org/PathwayBrowser/#/R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 TAS Homo sapiens 64607 R-HSA-6788556 https://reactome.org/PathwayBrowser/#/R-HSA-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 TAS Homo sapiens 64607 R-HSA-6799179 https://reactome.org/PathwayBrowser/#/R-HSA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex TAS Homo sapiens 64607 R-HSA-6799196 https://reactome.org/PathwayBrowser/#/R-HSA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I TAS Homo sapiens 64607 R-HSA-6800870 https://reactome.org/PathwayBrowser/#/R-HSA-6800870 NDUF subunits bind to form the FP subcomplex TAS Homo sapiens 64607 R-HSA-70994 https://reactome.org/PathwayBrowser/#/R-HSA-70994 SDH complex dehydrogenates succinate TAS Homo sapiens 64607 R-HSA-9855252 https://reactome.org/PathwayBrowser/#/R-HSA-9855252 SDHA:SDHB binds to SDHC:SDHD TAS Homo sapiens 64607 R-MMU-163217 https://reactome.org/PathwayBrowser/#/R-MMU-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Mus musculus 64607 R-MMU-6788556 https://reactome.org/PathwayBrowser/#/R-MMU-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Mus musculus 64607 R-MMU-6799179 https://reactome.org/PathwayBrowser/#/R-MMU-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Mus musculus 64607 R-MMU-6799196 https://reactome.org/PathwayBrowser/#/R-MMU-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Mus musculus 64607 R-MMU-6800870 https://reactome.org/PathwayBrowser/#/R-MMU-6800870 NDUF subunits bind to form the FP subcomplex IEA Mus musculus 64607 R-MMU-70994 https://reactome.org/PathwayBrowser/#/R-MMU-70994 SDH complex dehydrogenates succinate IEA Mus musculus 64607 R-MMU-9855252 https://reactome.org/PathwayBrowser/#/R-MMU-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Mus musculus 64607 R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Rattus norvegicus 64607 R-RNO-6788556 https://reactome.org/PathwayBrowser/#/R-RNO-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Rattus norvegicus 64607 R-RNO-6799179 https://reactome.org/PathwayBrowser/#/R-RNO-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Rattus norvegicus 64607 R-RNO-6799196 https://reactome.org/PathwayBrowser/#/R-RNO-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Rattus norvegicus 64607 R-RNO-6800870 https://reactome.org/PathwayBrowser/#/R-RNO-6800870 NDUF subunits bind to form the FP subcomplex IEA Rattus norvegicus 64607 R-RNO-70994 https://reactome.org/PathwayBrowser/#/R-RNO-70994 SDH complex dehydrogenates succinate IEA Rattus norvegicus 64607 R-SCE-70994 https://reactome.org/PathwayBrowser/#/R-SCE-70994 SDH complex dehydrogenates succinate IEA Saccharomyces cerevisiae 64607 R-SPO-70994 https://reactome.org/PathwayBrowser/#/R-SPO-70994 SDH complex dehydrogenates succinate IEA Schizosaccharomyces pombe 64607 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Sus scrofa 64607 R-SSC-6788556 https://reactome.org/PathwayBrowser/#/R-SSC-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Sus scrofa 64607 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa 64607 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa 64607 R-SSC-70994 https://reactome.org/PathwayBrowser/#/R-SSC-70994 SDH complex dehydrogenates succinate IEA Sus scrofa 64607 R-SSC-9855252 https://reactome.org/PathwayBrowser/#/R-SSC-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Sus scrofa 64607 R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to QH2 IEA Xenopus tropicalis 64607 R-XTR-6788556 https://reactome.org/PathwayBrowser/#/R-XTR-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Xenopus tropicalis 64607 R-XTR-70994 https://reactome.org/PathwayBrowser/#/R-XTR-70994 SDH complex dehydrogenates succinate IEA Xenopus tropicalis 64607 R-XTR-9855252 https://reactome.org/PathwayBrowser/#/R-XTR-9855252 SDHA:SDHB binds to SDHC:SDHD IEA Xenopus tropicalis 64612 R-BTA-8959462 https://reactome.org/PathwayBrowser/#/R-BTA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Bos taurus 64612 R-CEL-8959462 https://reactome.org/PathwayBrowser/#/R-CEL-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Caenorhabditis elegans 64612 R-CFA-8959462 https://reactome.org/PathwayBrowser/#/R-CFA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Canis familiaris 64612 R-DME-8959462 https://reactome.org/PathwayBrowser/#/R-DME-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Drosophila melanogaster 64612 R-DRE-8959462 https://reactome.org/PathwayBrowser/#/R-DRE-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Danio rerio 64612 R-GGA-8959462 https://reactome.org/PathwayBrowser/#/R-GGA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Gallus gallus 64612 R-HSA-8959462 https://reactome.org/PathwayBrowser/#/R-HSA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER TAS Homo sapiens 64612 R-MMU-8959462 https://reactome.org/PathwayBrowser/#/R-MMU-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Mus musculus 64612 R-PFA-8959462 https://reactome.org/PathwayBrowser/#/R-PFA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Plasmodium falciparum 64612 R-RNO-8959462 https://reactome.org/PathwayBrowser/#/R-RNO-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Rattus norvegicus 64612 R-SSC-8959462 https://reactome.org/PathwayBrowser/#/R-SSC-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Sus scrofa 64612 R-XTR-8959462 https://reactome.org/PathwayBrowser/#/R-XTR-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Xenopus tropicalis 64654 R-HSA-6782286 https://reactome.org/PathwayBrowser/#/R-HSA-6782286 METTL1:WDR4 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 IEA Homo sapiens 64654 R-HSA-6782416 https://reactome.org/PathwayBrowser/#/R-HSA-6782416 TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) TAS Homo sapiens 64654 R-HSA-6782443 https://reactome.org/PathwayBrowser/#/R-HSA-6782443 QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr) TAS Homo sapiens 64654 R-HSA-6782859 https://reactome.org/PathwayBrowser/#/R-HSA-6782859 TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 64654 R-HSA-6786501 https://reactome.org/PathwayBrowser/#/R-HSA-6786501 TRMT11:TRMT112 methylates guanosine-10 in tRNA IEA Homo sapiens 64654 R-HSA-6786621 https://reactome.org/PathwayBrowser/#/R-HSA-6786621 TRMT10A methylates guanosine-9 in tRNA IEA Homo sapiens 64654 R-HSA-6787591 https://reactome.org/PathwayBrowser/#/R-HSA-6787591 TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9 TAS Homo sapiens 64654 R-SCE-6783396 https://reactome.org/PathwayBrowser/#/R-SCE-6783396 TRM5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 64654 R-SCE-6786492 https://reactome.org/PathwayBrowser/#/R-SCE-6786492 TRM11:TRM112 methylates guanosine-10 in tRNA yielding N(2)-methylguanosine-10 TAS Saccharomyces cerevisiae 64654 R-SCE-6786632 https://reactome.org/PathwayBrowser/#/R-SCE-6786632 TRM10 methylates guanosine-9 in tRNA TAS Saccharomyces cerevisiae 64654 R-SCE-6790175 https://reactome.org/PathwayBrowser/#/R-SCE-6790175 TRM8:TRM82 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 TAS Saccharomyces cerevisiae 64656 R-HSA-6782388 https://reactome.org/PathwayBrowser/#/R-HSA-6782388 NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) IEA Homo sapiens 64656 R-HSA-6782419 https://reactome.org/PathwayBrowser/#/R-HSA-6782419 TRDMT1 (DNMT2) methylates cytidine-38 of tRNA(Asp) TAS Homo sapiens 64656 R-HSA-6785409 https://reactome.org/PathwayBrowser/#/R-HSA-6785409 NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) IEA Homo sapiens 64656 R-HSA-6785438 https://reactome.org/PathwayBrowser/#/R-HSA-6785438 NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) TAS Homo sapiens 64656 R-HSA-6788684 https://reactome.org/PathwayBrowser/#/R-HSA-6788684 TRMT13 2'-O-methylates cytidine-4 in tRNA IEA Homo sapiens 64656 R-SCE-6788683 https://reactome.org/PathwayBrowser/#/R-SCE-6788683 TRM13 2'-O-methylates cytidine-4 in tRNA TAS Saccharomyces cerevisiae 64656 R-SCE-6790149 https://reactome.org/PathwayBrowser/#/R-SCE-6790149 NCL1 (TRM4) methylates cytidine-49 of tRNA(Asp) yielding 5-methylcytidine-46 TAS Saccharomyces cerevisiae 64656 R-SCE-6790189 https://reactome.org/PathwayBrowser/#/R-SCE-6790189 NCL1 (TRM4) methylates cytidine-34 of unspliced tRNA(Leu) yielding 5-methylcytidine-34 TAS Saccharomyces cerevisiae 64681 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 64681 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 64681 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 64681 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 64681 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 64685 R-BTA-5263614 https://reactome.org/PathwayBrowser/#/R-BTA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Bos taurus 64685 R-CEL-5263614 https://reactome.org/PathwayBrowser/#/R-CEL-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Caenorhabditis elegans 64685 R-GGA-5263614 https://reactome.org/PathwayBrowser/#/R-GGA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Gallus gallus 64685 R-HSA-2408530 https://reactome.org/PathwayBrowser/#/R-HSA-2408530 MeSeH is hydrolysed to H2Se by methylselenol demethylase IEA Homo sapiens 64685 R-HSA-2408536 https://reactome.org/PathwayBrowser/#/R-HSA-2408536 H2Se is methylated to MeSeH by H2Se methyltransferase IEA Homo sapiens 64685 R-HSA-2408537 https://reactome.org/PathwayBrowser/#/R-HSA-2408537 Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH IEA Homo sapiens 64685 R-HSA-2408539 https://reactome.org/PathwayBrowser/#/R-HSA-2408539 MeSec is hydrolysed to MeSeH by PXLP-K212-CTH IEA Homo sapiens 64685 R-HSA-2408541 https://reactome.org/PathwayBrowser/#/R-HSA-2408541 MeSeH is methylated to Me2Se by MeSeH methyltransferase IEA Homo sapiens 64685 R-HSA-5263614 https://reactome.org/PathwayBrowser/#/R-HSA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 TAS Homo sapiens 64685 R-HSA-5333609 https://reactome.org/PathwayBrowser/#/R-HSA-5333609 MeSebGalNac is hydrolysed to MeSeH and bGalNac IEA Homo sapiens 64685 R-MMU-2408528 https://reactome.org/PathwayBrowser/#/R-MMU-2408528 Excess SeMet is cleaved into MeSeH by PXLP-K211-Cth TAS Mus musculus 64685 R-MMU-5263614 https://reactome.org/PathwayBrowser/#/R-MMU-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Mus musculus 64685 R-PFA-5263614 https://reactome.org/PathwayBrowser/#/R-PFA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Plasmodium falciparum 64685 R-RNO-2408501 https://reactome.org/PathwayBrowser/#/R-RNO-2408501 MeSeH is methylated to Me2Se by MeSeH methyltransferase TAS Rattus norvegicus 64685 R-RNO-2408511 https://reactome.org/PathwayBrowser/#/R-RNO-2408511 H2Se is methylated to MeSeH by H2Se methyltransferase TAS Rattus norvegicus 64685 R-RNO-2408521 https://reactome.org/PathwayBrowser/#/R-RNO-2408521 MeSeH is hydrolysed to H2Se by methylselenol demethylase TAS Rattus norvegicus 64685 R-RNO-2408538 https://reactome.org/PathwayBrowser/#/R-RNO-2408538 MeSec is hydrolysed to MeSeH by PXLP-K211-Cth TAS Rattus norvegicus 64685 R-RNO-5263614 https://reactome.org/PathwayBrowser/#/R-RNO-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Rattus norvegicus 64685 R-RNO-5333611 https://reactome.org/PathwayBrowser/#/R-RNO-5333611 MeSebGalNac is hydrolysed to MeSeH and bGalNac TAS Rattus norvegicus 64689 R-BTA-5694563 https://reactome.org/PathwayBrowser/#/R-BTA-5694563 ABHD10 hydrolyses MPAG IEA Bos taurus 64689 R-CFA-5694563 https://reactome.org/PathwayBrowser/#/R-CFA-5694563 ABHD10 hydrolyses MPAG IEA Canis familiaris 64689 R-GGA-5694563 https://reactome.org/PathwayBrowser/#/R-GGA-5694563 ABHD10 hydrolyses MPAG IEA Gallus gallus 64689 R-HSA-5694563 https://reactome.org/PathwayBrowser/#/R-HSA-5694563 ABHD10 hydrolyses MPAG TAS Homo sapiens 64689 R-MMU-5694563 https://reactome.org/PathwayBrowser/#/R-MMU-5694563 ABHD10 hydrolyses MPAG IEA Mus musculus 64689 R-RNO-5694563 https://reactome.org/PathwayBrowser/#/R-RNO-5694563 ABHD10 hydrolyses MPAG IEA Rattus norvegicus 64689 R-SSC-5694563 https://reactome.org/PathwayBrowser/#/R-SSC-5694563 ABHD10 hydrolyses MPAG IEA Sus scrofa 64689 R-XTR-5694563 https://reactome.org/PathwayBrowser/#/R-XTR-5694563 ABHD10 hydrolyses MPAG IEA Xenopus tropicalis 64716 R-BTA-1482539 https://reactome.org/PathwayBrowser/#/R-BTA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Bos taurus 64716 R-BTA-1482546 https://reactome.org/PathwayBrowser/#/R-BTA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Bos taurus 64716 R-BTA-1482635 https://reactome.org/PathwayBrowser/#/R-BTA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Bos taurus 64716 R-BTA-1482689 https://reactome.org/PathwayBrowser/#/R-BTA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Bos taurus 64716 R-BTA-1482745 https://reactome.org/PathwayBrowser/#/R-BTA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Bos taurus 64716 R-BTA-1482847 https://reactome.org/PathwayBrowser/#/R-BTA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Bos taurus 64716 R-BTA-1482900 https://reactome.org/PathwayBrowser/#/R-BTA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Bos taurus 64716 R-BTA-1482907 https://reactome.org/PathwayBrowser/#/R-BTA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Bos taurus 64716 R-BTA-1482920 https://reactome.org/PathwayBrowser/#/R-BTA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Bos taurus 64716 R-BTA-1483063 https://reactome.org/PathwayBrowser/#/R-BTA-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Bos taurus 64716 R-BTA-1602368 https://reactome.org/PathwayBrowser/#/R-BTA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Bos taurus 64716 R-BTA-5683714 https://reactome.org/PathwayBrowser/#/R-BTA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Bos taurus 64716 R-BTA-5684862 https://reactome.org/PathwayBrowser/#/R-BTA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Bos taurus 64716 R-BTA-8850326 https://reactome.org/PathwayBrowser/#/R-BTA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Bos taurus 64716 R-BTA-8954398 https://reactome.org/PathwayBrowser/#/R-BTA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Bos taurus 64716 R-CEL-1482539 https://reactome.org/PathwayBrowser/#/R-CEL-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Caenorhabditis elegans 64716 R-CEL-1482546 https://reactome.org/PathwayBrowser/#/R-CEL-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Caenorhabditis elegans 64716 R-CEL-1482635 https://reactome.org/PathwayBrowser/#/R-CEL-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Caenorhabditis elegans 64716 R-CEL-1482689 https://reactome.org/PathwayBrowser/#/R-CEL-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Caenorhabditis elegans 64716 R-CEL-1482900 https://reactome.org/PathwayBrowser/#/R-CEL-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Caenorhabditis elegans 64716 R-CEL-1482907 https://reactome.org/PathwayBrowser/#/R-CEL-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Caenorhabditis elegans 64716 R-CEL-1483063 https://reactome.org/PathwayBrowser/#/R-CEL-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Caenorhabditis elegans 64716 R-CEL-1602368 https://reactome.org/PathwayBrowser/#/R-CEL-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Caenorhabditis elegans 64716 R-CEL-5683714 https://reactome.org/PathwayBrowser/#/R-CEL-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Caenorhabditis elegans 64716 R-CFA-1482539 https://reactome.org/PathwayBrowser/#/R-CFA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Canis familiaris 64716 R-CFA-1482635 https://reactome.org/PathwayBrowser/#/R-CFA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Canis familiaris 64716 R-CFA-1482745 https://reactome.org/PathwayBrowser/#/R-CFA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Canis familiaris 64716 R-CFA-1482847 https://reactome.org/PathwayBrowser/#/R-CFA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Canis familiaris 64716 R-CFA-1482900 https://reactome.org/PathwayBrowser/#/R-CFA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Canis familiaris 64716 R-CFA-1482920 https://reactome.org/PathwayBrowser/#/R-CFA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Canis familiaris 64716 R-CFA-1602368 https://reactome.org/PathwayBrowser/#/R-CFA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Canis familiaris 64716 R-CFA-5683714 https://reactome.org/PathwayBrowser/#/R-CFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Canis familiaris 64716 R-CFA-5684862 https://reactome.org/PathwayBrowser/#/R-CFA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Canis familiaris 64716 R-CFA-8850326 https://reactome.org/PathwayBrowser/#/R-CFA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Canis familiaris 64716 R-CFA-8954398 https://reactome.org/PathwayBrowser/#/R-CFA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Canis familiaris 64716 R-DDI-1482539 https://reactome.org/PathwayBrowser/#/R-DDI-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Dictyostelium discoideum 64716 R-DDI-1482635 https://reactome.org/PathwayBrowser/#/R-DDI-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Dictyostelium discoideum 64716 R-DDI-5683714 https://reactome.org/PathwayBrowser/#/R-DDI-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Dictyostelium discoideum 64716 R-DDI-8954398 https://reactome.org/PathwayBrowser/#/R-DDI-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Dictyostelium discoideum 64716 R-DME-1482539 https://reactome.org/PathwayBrowser/#/R-DME-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Drosophila melanogaster 64716 R-DME-1482546 https://reactome.org/PathwayBrowser/#/R-DME-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Drosophila melanogaster 64716 R-DME-1482635 https://reactome.org/PathwayBrowser/#/R-DME-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Drosophila melanogaster 64716 R-DME-1482689 https://reactome.org/PathwayBrowser/#/R-DME-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Drosophila melanogaster 64716 R-DME-1482900 https://reactome.org/PathwayBrowser/#/R-DME-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Drosophila melanogaster 64716 R-DME-1482907 https://reactome.org/PathwayBrowser/#/R-DME-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Drosophila melanogaster 64716 R-DME-1483063 https://reactome.org/PathwayBrowser/#/R-DME-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Drosophila melanogaster 64716 R-DME-1602368 https://reactome.org/PathwayBrowser/#/R-DME-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Drosophila melanogaster 64716 R-DME-5683714 https://reactome.org/PathwayBrowser/#/R-DME-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Drosophila melanogaster 64716 R-DME-8954398 https://reactome.org/PathwayBrowser/#/R-DME-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Drosophila melanogaster 64716 R-DRE-1482539 https://reactome.org/PathwayBrowser/#/R-DRE-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Danio rerio 64716 R-DRE-1482546 https://reactome.org/PathwayBrowser/#/R-DRE-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Danio rerio 64716 R-DRE-1482635 https://reactome.org/PathwayBrowser/#/R-DRE-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Danio rerio 64716 R-DRE-1482689 https://reactome.org/PathwayBrowser/#/R-DRE-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Danio rerio 64716 R-DRE-1482900 https://reactome.org/PathwayBrowser/#/R-DRE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Danio rerio 64716 R-DRE-1483063 https://reactome.org/PathwayBrowser/#/R-DRE-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Danio rerio 64716 R-DRE-1602368 https://reactome.org/PathwayBrowser/#/R-DRE-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Danio rerio 64716 R-DRE-8954398 https://reactome.org/PathwayBrowser/#/R-DRE-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Danio rerio 64716 R-GGA-1482539 https://reactome.org/PathwayBrowser/#/R-GGA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Gallus gallus 64716 R-GGA-1482546 https://reactome.org/PathwayBrowser/#/R-GGA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Gallus gallus 64716 R-GGA-1482635 https://reactome.org/PathwayBrowser/#/R-GGA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Gallus gallus 64716 R-GGA-1482689 https://reactome.org/PathwayBrowser/#/R-GGA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Gallus gallus 64716 R-GGA-1482745 https://reactome.org/PathwayBrowser/#/R-GGA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Gallus gallus 64716 R-GGA-1482847 https://reactome.org/PathwayBrowser/#/R-GGA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Gallus gallus 64716 R-GGA-1482900 https://reactome.org/PathwayBrowser/#/R-GGA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Gallus gallus 64716 R-GGA-1482907 https://reactome.org/PathwayBrowser/#/R-GGA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Gallus gallus 64716 R-GGA-1482920 https://reactome.org/PathwayBrowser/#/R-GGA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Gallus gallus 64716 R-GGA-1483063 https://reactome.org/PathwayBrowser/#/R-GGA-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Gallus gallus 64716 R-GGA-1602368 https://reactome.org/PathwayBrowser/#/R-GGA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Gallus gallus 64716 R-GGA-5683714 https://reactome.org/PathwayBrowser/#/R-GGA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Gallus gallus 64716 R-GGA-5684862 https://reactome.org/PathwayBrowser/#/R-GGA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Gallus gallus 64716 R-GGA-8850326 https://reactome.org/PathwayBrowser/#/R-GGA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Gallus gallus 64716 R-GGA-8954398 https://reactome.org/PathwayBrowser/#/R-GGA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Gallus gallus 64716 R-HSA-1482539 https://reactome.org/PathwayBrowser/#/R-HSA-1482539 1-acyl LPG is acylated to PG by LPGAT TAS Homo sapiens 64716 R-HSA-1482546 https://reactome.org/PathwayBrowser/#/R-HSA-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) TAS Homo sapiens 64716 R-HSA-1482635 https://reactome.org/PathwayBrowser/#/R-HSA-1482635 2-acyl LPG is acylated to PG by LPGAT TAS Homo sapiens 64716 R-HSA-1482689 https://reactome.org/PathwayBrowser/#/R-HSA-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) TAS Homo sapiens 64716 R-HSA-1482745 https://reactome.org/PathwayBrowser/#/R-HSA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) TAS Homo sapiens 64716 R-HSA-1482847 https://reactome.org/PathwayBrowser/#/R-HSA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) TAS Homo sapiens 64716 R-HSA-1482900 https://reactome.org/PathwayBrowser/#/R-HSA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] TAS Homo sapiens 64716 R-HSA-1482907 https://reactome.org/PathwayBrowser/#/R-HSA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A TAS Homo sapiens 64716 R-HSA-1482920 https://reactome.org/PathwayBrowser/#/R-HSA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] TAS Homo sapiens 64716 R-HSA-1483063 https://reactome.org/PathwayBrowser/#/R-HSA-1483063 PG and CDP-DAG are converted to CL by CRLS1 TAS Homo sapiens 64716 R-HSA-1483142 https://reactome.org/PathwayBrowser/#/R-HSA-1483142 PC is transphosphatidylated to PG by PLD1-4/6 IEA Homo sapiens 64716 R-HSA-1483197 https://reactome.org/PathwayBrowser/#/R-HSA-1483197 PTPMT1 dephosphorylates PGP to PG IEA Homo sapiens 64716 R-HSA-1483209 https://reactome.org/PathwayBrowser/#/R-HSA-1483209 PG is converted to BMP TAS Homo sapiens 64716 R-HSA-1483218 https://reactome.org/PathwayBrowser/#/R-HSA-1483218 PG transports from the ER membrane to the late endosome membrane TAS Homo sapiens 64716 R-HSA-1602368 https://reactome.org/PathwayBrowser/#/R-HSA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] TAS Homo sapiens 64716 R-HSA-5683672 https://reactome.org/PathwayBrowser/#/R-HSA-5683672 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body TAS Homo sapiens 64716 R-HSA-5683714 https://reactome.org/PathwayBrowser/#/R-HSA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body TAS Homo sapiens 64716 R-HSA-5684862 https://reactome.org/PathwayBrowser/#/R-HSA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. TAS Homo sapiens 64716 R-HSA-5688397 https://reactome.org/PathwayBrowser/#/R-HSA-5688397 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body TAS Homo sapiens 64716 R-HSA-8850326 https://reactome.org/PathwayBrowser/#/R-HSA-8850326 TCR binds self-lipid-based antigen via CD1 TAS Homo sapiens 64716 R-HSA-8954398 https://reactome.org/PathwayBrowser/#/R-HSA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG TAS Homo sapiens 64716 R-MMU-1482539 https://reactome.org/PathwayBrowser/#/R-MMU-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Mus musculus 64716 R-MMU-1482546 https://reactome.org/PathwayBrowser/#/R-MMU-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Mus musculus 64716 R-MMU-1482635 https://reactome.org/PathwayBrowser/#/R-MMU-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Mus musculus 64716 R-MMU-1482689 https://reactome.org/PathwayBrowser/#/R-MMU-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Mus musculus 64716 R-MMU-1482745 https://reactome.org/PathwayBrowser/#/R-MMU-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Mus musculus 64716 R-MMU-1482847 https://reactome.org/PathwayBrowser/#/R-MMU-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Mus musculus 64716 R-MMU-1482900 https://reactome.org/PathwayBrowser/#/R-MMU-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Mus musculus 64716 R-MMU-1482907 https://reactome.org/PathwayBrowser/#/R-MMU-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Mus musculus 64716 R-MMU-1482920 https://reactome.org/PathwayBrowser/#/R-MMU-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Mus musculus 64716 R-MMU-1483063 https://reactome.org/PathwayBrowser/#/R-MMU-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Mus musculus 64716 R-MMU-1483172 https://reactome.org/PathwayBrowser/#/R-MMU-1483172 PC is transphosphatidylated to PG by Pld1-4/6 TAS Mus musculus 64716 R-MMU-1602368 https://reactome.org/PathwayBrowser/#/R-MMU-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Mus musculus 64716 R-MMU-3446785 https://reactome.org/PathwayBrowser/#/R-MMU-3446785 Ptpmt1 dephosphorylates PGP to PG TAS Mus musculus 64716 R-MMU-5683714 https://reactome.org/PathwayBrowser/#/R-MMU-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Mus musculus 64716 R-MMU-5684862 https://reactome.org/PathwayBrowser/#/R-MMU-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Mus musculus 64716 R-MMU-8850326 https://reactome.org/PathwayBrowser/#/R-MMU-8850326 TCR binds self-lipid-based antigen via CD1 IEA Mus musculus 64716 R-MMU-8954398 https://reactome.org/PathwayBrowser/#/R-MMU-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Mus musculus 64716 R-PFA-1482539 https://reactome.org/PathwayBrowser/#/R-PFA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Plasmodium falciparum 64716 R-PFA-1482635 https://reactome.org/PathwayBrowser/#/R-PFA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Plasmodium falciparum 64716 R-PFA-5683714 https://reactome.org/PathwayBrowser/#/R-PFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Plasmodium falciparum 64716 R-RNO-1482539 https://reactome.org/PathwayBrowser/#/R-RNO-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Rattus norvegicus 64716 R-RNO-1482546 https://reactome.org/PathwayBrowser/#/R-RNO-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Rattus norvegicus 64716 R-RNO-1482635 https://reactome.org/PathwayBrowser/#/R-RNO-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Rattus norvegicus 64716 R-RNO-1482689 https://reactome.org/PathwayBrowser/#/R-RNO-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Rattus norvegicus 64716 R-RNO-1482745 https://reactome.org/PathwayBrowser/#/R-RNO-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Rattus norvegicus 64716 R-RNO-1482847 https://reactome.org/PathwayBrowser/#/R-RNO-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Rattus norvegicus 64716 R-RNO-1482900 https://reactome.org/PathwayBrowser/#/R-RNO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Rattus norvegicus 64716 R-RNO-1482907 https://reactome.org/PathwayBrowser/#/R-RNO-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Rattus norvegicus 64716 R-RNO-1482920 https://reactome.org/PathwayBrowser/#/R-RNO-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Rattus norvegicus 64716 R-RNO-1483063 https://reactome.org/PathwayBrowser/#/R-RNO-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Rattus norvegicus 64716 R-RNO-1602368 https://reactome.org/PathwayBrowser/#/R-RNO-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Rattus norvegicus 64716 R-RNO-5683714 https://reactome.org/PathwayBrowser/#/R-RNO-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Rattus norvegicus 64716 R-RNO-5684862 https://reactome.org/PathwayBrowser/#/R-RNO-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Rattus norvegicus 64716 R-RNO-8850326 https://reactome.org/PathwayBrowser/#/R-RNO-8850326 TCR binds self-lipid-based antigen via CD1 IEA Rattus norvegicus 64716 R-RNO-8954398 https://reactome.org/PathwayBrowser/#/R-RNO-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Rattus norvegicus 64716 R-SCE-1482539 https://reactome.org/PathwayBrowser/#/R-SCE-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Saccharomyces cerevisiae 64716 R-SCE-1482546 https://reactome.org/PathwayBrowser/#/R-SCE-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Saccharomyces cerevisiae 64716 R-SCE-1482635 https://reactome.org/PathwayBrowser/#/R-SCE-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Saccharomyces cerevisiae 64716 R-SCE-1482689 https://reactome.org/PathwayBrowser/#/R-SCE-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Saccharomyces cerevisiae 64716 R-SCE-1482745 https://reactome.org/PathwayBrowser/#/R-SCE-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Saccharomyces cerevisiae 64716 R-SCE-1482847 https://reactome.org/PathwayBrowser/#/R-SCE-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Saccharomyces cerevisiae 64716 R-SCE-1482900 https://reactome.org/PathwayBrowser/#/R-SCE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Saccharomyces cerevisiae 64716 R-SCE-1482920 https://reactome.org/PathwayBrowser/#/R-SCE-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Saccharomyces cerevisiae 64716 R-SCE-1483063 https://reactome.org/PathwayBrowser/#/R-SCE-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Saccharomyces cerevisiae 64716 R-SPO-1482539 https://reactome.org/PathwayBrowser/#/R-SPO-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Schizosaccharomyces pombe 64716 R-SPO-1482546 https://reactome.org/PathwayBrowser/#/R-SPO-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Schizosaccharomyces pombe 64716 R-SPO-1482635 https://reactome.org/PathwayBrowser/#/R-SPO-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Schizosaccharomyces pombe 64716 R-SPO-1482689 https://reactome.org/PathwayBrowser/#/R-SPO-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Schizosaccharomyces pombe 64716 R-SPO-1482745 https://reactome.org/PathwayBrowser/#/R-SPO-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Schizosaccharomyces pombe 64716 R-SPO-1482847 https://reactome.org/PathwayBrowser/#/R-SPO-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Schizosaccharomyces pombe 64716 R-SPO-1482900 https://reactome.org/PathwayBrowser/#/R-SPO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Schizosaccharomyces pombe 64716 R-SPO-1482920 https://reactome.org/PathwayBrowser/#/R-SPO-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Schizosaccharomyces pombe 64716 R-SPO-1483063 https://reactome.org/PathwayBrowser/#/R-SPO-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Schizosaccharomyces pombe 64716 R-SSC-1482539 https://reactome.org/PathwayBrowser/#/R-SSC-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa 64716 R-SSC-1482546 https://reactome.org/PathwayBrowser/#/R-SSC-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Sus scrofa 64716 R-SSC-1482635 https://reactome.org/PathwayBrowser/#/R-SSC-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa 64716 R-SSC-1482689 https://reactome.org/PathwayBrowser/#/R-SSC-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Sus scrofa 64716 R-SSC-1482745 https://reactome.org/PathwayBrowser/#/R-SSC-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Sus scrofa 64716 R-SSC-1482847 https://reactome.org/PathwayBrowser/#/R-SSC-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Sus scrofa 64716 R-SSC-1482900 https://reactome.org/PathwayBrowser/#/R-SSC-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Sus scrofa 64716 R-SSC-1482907 https://reactome.org/PathwayBrowser/#/R-SSC-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Sus scrofa 64716 R-SSC-1482920 https://reactome.org/PathwayBrowser/#/R-SSC-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Sus scrofa 64716 R-SSC-1483063 https://reactome.org/PathwayBrowser/#/R-SSC-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Sus scrofa 64716 R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa 64716 R-SSC-5683714 https://reactome.org/PathwayBrowser/#/R-SSC-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Sus scrofa 64716 R-SSC-5684862 https://reactome.org/PathwayBrowser/#/R-SSC-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Sus scrofa 64716 R-SSC-8850326 https://reactome.org/PathwayBrowser/#/R-SSC-8850326 TCR binds self-lipid-based antigen via CD1 IEA Sus scrofa 64716 R-SSC-8954398 https://reactome.org/PathwayBrowser/#/R-SSC-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Sus scrofa 64716 R-XTR-1482539 https://reactome.org/PathwayBrowser/#/R-XTR-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Xenopus tropicalis 64716 R-XTR-1482635 https://reactome.org/PathwayBrowser/#/R-XTR-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Xenopus tropicalis 64716 R-XTR-1482745 https://reactome.org/PathwayBrowser/#/R-XTR-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Xenopus tropicalis 64716 R-XTR-1482847 https://reactome.org/PathwayBrowser/#/R-XTR-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Xenopus tropicalis 64716 R-XTR-1482900 https://reactome.org/PathwayBrowser/#/R-XTR-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Xenopus tropicalis 64716 R-XTR-1482907 https://reactome.org/PathwayBrowser/#/R-XTR-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Xenopus tropicalis 64716 R-XTR-1482920 https://reactome.org/PathwayBrowser/#/R-XTR-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Xenopus tropicalis 64716 R-XTR-1602368 https://reactome.org/PathwayBrowser/#/R-XTR-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Xenopus tropicalis 64716 R-XTR-5683714 https://reactome.org/PathwayBrowser/#/R-XTR-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Xenopus tropicalis 64716 R-XTR-8954398 https://reactome.org/PathwayBrowser/#/R-XTR-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Xenopus tropicalis 64729 R-HSA-2408500 https://reactome.org/PathwayBrowser/#/R-HSA-2408500 GSSeH condenses with GSH to form H2Se and GSSG IEA Homo sapiens 64729 R-HSA-2408542 https://reactome.org/PathwayBrowser/#/R-HSA-2408542 GSSeSG is reduced to GSSeH and GSH by GSR IEA Homo sapiens 64729 R-HSA-5333607 https://reactome.org/PathwayBrowser/#/R-HSA-5333607 GSSeH combines with bGalNAc derivative to form GSSebGalNac IEA Homo sapiens 64729 R-RNO-2408514 https://reactome.org/PathwayBrowser/#/R-RNO-2408514 GSSeSG is reduced to GSSeH and GSH by Gsr TAS Rattus norvegicus 64729 R-RNO-2408520 https://reactome.org/PathwayBrowser/#/R-RNO-2408520 GSSeH condenses with GSH to form H2Se and GSSG TAS Rattus norvegicus 64729 R-RNO-5333617 https://reactome.org/PathwayBrowser/#/R-RNO-5333617 GSSeH combines with bGalNAc derivative to form GSSebGalNac TAS Rattus norvegicus 64972 R-BTA-390251 https://reactome.org/PathwayBrowser/#/R-BTA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 64972 R-BTA-390252 https://reactome.org/PathwayBrowser/#/R-BTA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Bos taurus 64972 R-BTA-6809263 https://reactome.org/PathwayBrowser/#/R-BTA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Bos taurus 64972 R-BTA-6809264 https://reactome.org/PathwayBrowser/#/R-BTA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 64972 R-CEL-390251 https://reactome.org/PathwayBrowser/#/R-CEL-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 64972 R-CEL-390252 https://reactome.org/PathwayBrowser/#/R-CEL-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Caenorhabditis elegans 64972 R-CEL-6809263 https://reactome.org/PathwayBrowser/#/R-CEL-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Caenorhabditis elegans 64972 R-CEL-6809264 https://reactome.org/PathwayBrowser/#/R-CEL-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 64972 R-CFA-390251 https://reactome.org/PathwayBrowser/#/R-CFA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 64972 R-CFA-390252 https://reactome.org/PathwayBrowser/#/R-CFA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Canis familiaris 64972 R-CFA-6809263 https://reactome.org/PathwayBrowser/#/R-CFA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Canis familiaris 64972 R-CFA-6809264 https://reactome.org/PathwayBrowser/#/R-CFA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 64972 R-DDI-390251 https://reactome.org/PathwayBrowser/#/R-DDI-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Dictyostelium discoideum 64972 R-DDI-390252 https://reactome.org/PathwayBrowser/#/R-DDI-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Dictyostelium discoideum 64972 R-DME-390251 https://reactome.org/PathwayBrowser/#/R-DME-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Drosophila melanogaster 64972 R-DME-390252 https://reactome.org/PathwayBrowser/#/R-DME-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Drosophila melanogaster 64972 R-DRE-6809263 https://reactome.org/PathwayBrowser/#/R-DRE-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Danio rerio 64972 R-DRE-6809264 https://reactome.org/PathwayBrowser/#/R-DRE-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Danio rerio 64972 R-GGA-390251 https://reactome.org/PathwayBrowser/#/R-GGA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 64972 R-GGA-390252 https://reactome.org/PathwayBrowser/#/R-GGA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Gallus gallus 64972 R-GGA-6809263 https://reactome.org/PathwayBrowser/#/R-GGA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Gallus gallus 64972 R-GGA-6809264 https://reactome.org/PathwayBrowser/#/R-GGA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 64972 R-HSA-390251 https://reactome.org/PathwayBrowser/#/R-HSA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 64972 R-HSA-390252 https://reactome.org/PathwayBrowser/#/R-HSA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA TAS Homo sapiens 64972 R-HSA-6809263 https://reactome.org/PathwayBrowser/#/R-HSA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA TAS Homo sapiens 64972 R-HSA-6809264 https://reactome.org/PathwayBrowser/#/R-HSA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 64972 R-MMU-390251 https://reactome.org/PathwayBrowser/#/R-MMU-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 64972 R-MMU-390252 https://reactome.org/PathwayBrowser/#/R-MMU-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Mus musculus 64972 R-MMU-6809263 https://reactome.org/PathwayBrowser/#/R-MMU-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Mus musculus 64972 R-MMU-6809264 https://reactome.org/PathwayBrowser/#/R-MMU-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 64972 R-RNO-390251 https://reactome.org/PathwayBrowser/#/R-RNO-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 64972 R-RNO-390252 https://reactome.org/PathwayBrowser/#/R-RNO-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Rattus norvegicus 64972 R-RNO-6809263 https://reactome.org/PathwayBrowser/#/R-RNO-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Rattus norvegicus 64972 R-RNO-6809264 https://reactome.org/PathwayBrowser/#/R-RNO-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 64972 R-SSC-6809263 https://reactome.org/PathwayBrowser/#/R-SSC-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Sus scrofa 64972 R-SSC-6809264 https://reactome.org/PathwayBrowser/#/R-SSC-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Sus scrofa 64972 R-XTR-6809263 https://reactome.org/PathwayBrowser/#/R-XTR-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Xenopus tropicalis 64972 R-XTR-6809264 https://reactome.org/PathwayBrowser/#/R-XTR-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Xenopus tropicalis 6498 R-BTA-2161775 https://reactome.org/PathwayBrowser/#/R-BTA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Bos taurus 6498 R-BTA-2161779 https://reactome.org/PathwayBrowser/#/R-BTA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Bos taurus 6498 R-BTA-2161917 https://reactome.org/PathwayBrowser/#/R-BTA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Bos taurus 6498 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 6498 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 6498 R-CFA-2161775 https://reactome.org/PathwayBrowser/#/R-CFA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Canis familiaris 6498 R-CFA-2161779 https://reactome.org/PathwayBrowser/#/R-CFA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Canis familiaris 6498 R-CFA-2161917 https://reactome.org/PathwayBrowser/#/R-CFA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Canis familiaris 6498 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 6498 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 6498 R-CFA-391913 https://reactome.org/PathwayBrowser/#/R-CFA-391913 FPR2 binds FPR2 ligands IEA Canis familiaris 6498 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 6498 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 6498 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 6498 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 6498 R-DDI-2161775 https://reactome.org/PathwayBrowser/#/R-DDI-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Dictyostelium discoideum 6498 R-DDI-2161917 https://reactome.org/PathwayBrowser/#/R-DDI-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Dictyostelium discoideum 6498 R-DME-2161779 https://reactome.org/PathwayBrowser/#/R-DME-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Drosophila melanogaster 6498 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 6498 R-DRE-2161775 https://reactome.org/PathwayBrowser/#/R-DRE-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Danio rerio 6498 R-DRE-2161779 https://reactome.org/PathwayBrowser/#/R-DRE-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Danio rerio 6498 R-GGA-2161779 https://reactome.org/PathwayBrowser/#/R-GGA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Gallus gallus 6498 R-GGA-2161917 https://reactome.org/PathwayBrowser/#/R-GGA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Gallus gallus 6498 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 6498 R-HSA-2161775 https://reactome.org/PathwayBrowser/#/R-HSA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 TAS Homo sapiens 6498 R-HSA-2161779 https://reactome.org/PathwayBrowser/#/R-HSA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD TAS Homo sapiens 6498 R-HSA-2161917 https://reactome.org/PathwayBrowser/#/R-HSA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 TAS Homo sapiens 6498 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 6498 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 6498 R-HSA-391913 https://reactome.org/PathwayBrowser/#/R-HSA-391913 FPR2 binds FPR2 ligands TAS Homo sapiens 6498 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 6498 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 6498 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 6498 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 6498 R-HSA-9032054 https://reactome.org/PathwayBrowser/#/R-HSA-9032054 LXA4/B4 translocate from cytosol to extracellular region TAS Homo sapiens 6498 R-MMU-2161775 https://reactome.org/PathwayBrowser/#/R-MMU-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Mus musculus 6498 R-MMU-2161779 https://reactome.org/PathwayBrowser/#/R-MMU-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Mus musculus 6498 R-MMU-2161917 https://reactome.org/PathwayBrowser/#/R-MMU-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Mus musculus 6498 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 6498 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 6498 R-MMU-391913 https://reactome.org/PathwayBrowser/#/R-MMU-391913 FPR2 binds FPR2 ligands IEA Mus musculus 6498 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 6498 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 6498 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 6498 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 6498 R-RNO-2161775 https://reactome.org/PathwayBrowser/#/R-RNO-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Rattus norvegicus 6498 R-RNO-2161779 https://reactome.org/PathwayBrowser/#/R-RNO-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Rattus norvegicus 6498 R-RNO-2161917 https://reactome.org/PathwayBrowser/#/R-RNO-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Rattus norvegicus 6498 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 6498 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 6498 R-RNO-391913 https://reactome.org/PathwayBrowser/#/R-RNO-391913 FPR2 binds FPR2 ligands IEA Rattus norvegicus 6498 R-SSC-2161775 https://reactome.org/PathwayBrowser/#/R-SSC-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Sus scrofa 6498 R-SSC-2161779 https://reactome.org/PathwayBrowser/#/R-SSC-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Sus scrofa 6498 R-SSC-2161917 https://reactome.org/PathwayBrowser/#/R-SSC-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Sus scrofa 6498 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 6498 R-XTR-2161779 https://reactome.org/PathwayBrowser/#/R-XTR-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Xenopus tropicalis 6498 R-XTR-2161917 https://reactome.org/PathwayBrowser/#/R-XTR-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Xenopus tropicalis 6498 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 6498 R-XTR-391913 https://reactome.org/PathwayBrowser/#/R-XTR-391913 FPR2 binds FPR2 ligands IEA Xenopus tropicalis 6498 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 6498 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 6498 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 6498 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 6499 R-BTA-2161775 https://reactome.org/PathwayBrowser/#/R-BTA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Bos taurus 6499 R-BTA-2161917 https://reactome.org/PathwayBrowser/#/R-BTA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Bos taurus 6499 R-CFA-2161775 https://reactome.org/PathwayBrowser/#/R-CFA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Canis familiaris 6499 R-CFA-2161917 https://reactome.org/PathwayBrowser/#/R-CFA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Canis familiaris 6499 R-DDI-2161775 https://reactome.org/PathwayBrowser/#/R-DDI-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Dictyostelium discoideum 6499 R-DDI-2161917 https://reactome.org/PathwayBrowser/#/R-DDI-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Dictyostelium discoideum 6499 R-DRE-2161775 https://reactome.org/PathwayBrowser/#/R-DRE-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Danio rerio 6499 R-GGA-2161917 https://reactome.org/PathwayBrowser/#/R-GGA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Gallus gallus 6499 R-HSA-2161775 https://reactome.org/PathwayBrowser/#/R-HSA-2161775 ALOX12 oxidises LTA4 to LXA4/B4 TAS Homo sapiens 6499 R-HSA-2161917 https://reactome.org/PathwayBrowser/#/R-HSA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 TAS Homo sapiens 6499 R-HSA-9032054 https://reactome.org/PathwayBrowser/#/R-HSA-9032054 LXA4/B4 translocate from cytosol to extracellular region TAS Homo sapiens 6499 R-MMU-2161775 https://reactome.org/PathwayBrowser/#/R-MMU-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Mus musculus 6499 R-MMU-2161917 https://reactome.org/PathwayBrowser/#/R-MMU-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Mus musculus 6499 R-RNO-2161775 https://reactome.org/PathwayBrowser/#/R-RNO-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Rattus norvegicus 6499 R-RNO-2161917 https://reactome.org/PathwayBrowser/#/R-RNO-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Rattus norvegicus 6499 R-SSC-2161775 https://reactome.org/PathwayBrowser/#/R-SSC-2161775 ALOX12 oxidises LTA4 to LXA4/B4 IEA Sus scrofa 6499 R-SSC-2161917 https://reactome.org/PathwayBrowser/#/R-SSC-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Sus scrofa 6499 R-XTR-2161917 https://reactome.org/PathwayBrowser/#/R-XTR-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Xenopus tropicalis 65049 R-BTA-200644 https://reactome.org/PathwayBrowser/#/R-BTA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Bos taurus 65049 R-BTA-200661 https://reactome.org/PathwayBrowser/#/R-BTA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Bos taurus 65049 R-BTA-200718 https://reactome.org/PathwayBrowser/#/R-BTA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Bos taurus 65049 R-BTA-200740 https://reactome.org/PathwayBrowser/#/R-BTA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Bos taurus 65049 R-BTA-6801342 https://reactome.org/PathwayBrowser/#/R-BTA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Bos taurus 65049 R-CEL-200644 https://reactome.org/PathwayBrowser/#/R-CEL-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Caenorhabditis elegans 65049 R-CEL-200661 https://reactome.org/PathwayBrowser/#/R-CEL-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Caenorhabditis elegans 65049 R-CEL-200718 https://reactome.org/PathwayBrowser/#/R-CEL-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Caenorhabditis elegans 65049 R-CEL-200740 https://reactome.org/PathwayBrowser/#/R-CEL-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Caenorhabditis elegans 65049 R-CEL-6801342 https://reactome.org/PathwayBrowser/#/R-CEL-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Caenorhabditis elegans 65049 R-CFA-200644 https://reactome.org/PathwayBrowser/#/R-CFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Canis familiaris 65049 R-CFA-200661 https://reactome.org/PathwayBrowser/#/R-CFA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Canis familiaris 65049 R-CFA-200718 https://reactome.org/PathwayBrowser/#/R-CFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Canis familiaris 65049 R-CFA-200740 https://reactome.org/PathwayBrowser/#/R-CFA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Canis familiaris 65049 R-CFA-6801342 https://reactome.org/PathwayBrowser/#/R-CFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Canis familiaris 65049 R-DDI-200644 https://reactome.org/PathwayBrowser/#/R-DDI-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Dictyostelium discoideum 65049 R-DDI-200661 https://reactome.org/PathwayBrowser/#/R-DDI-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Dictyostelium discoideum 65049 R-DDI-200718 https://reactome.org/PathwayBrowser/#/R-DDI-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Dictyostelium discoideum 65049 R-DDI-200740 https://reactome.org/PathwayBrowser/#/R-DDI-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Dictyostelium discoideum 65049 R-DME-200644 https://reactome.org/PathwayBrowser/#/R-DME-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Drosophila melanogaster 65049 R-DME-200661 https://reactome.org/PathwayBrowser/#/R-DME-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Drosophila melanogaster 65049 R-DME-200718 https://reactome.org/PathwayBrowser/#/R-DME-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Drosophila melanogaster 65049 R-DME-200740 https://reactome.org/PathwayBrowser/#/R-DME-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Drosophila melanogaster 65049 R-DME-6801342 https://reactome.org/PathwayBrowser/#/R-DME-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Drosophila melanogaster 65049 R-DRE-200644 https://reactome.org/PathwayBrowser/#/R-DRE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Danio rerio 65049 R-DRE-200661 https://reactome.org/PathwayBrowser/#/R-DRE-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio 65049 R-DRE-200718 https://reactome.org/PathwayBrowser/#/R-DRE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Danio rerio 65049 R-DRE-200740 https://reactome.org/PathwayBrowser/#/R-DRE-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Danio rerio 65049 R-DRE-6801342 https://reactome.org/PathwayBrowser/#/R-DRE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio 65049 R-GGA-200644 https://reactome.org/PathwayBrowser/#/R-GGA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Gallus gallus 65049 R-GGA-200661 https://reactome.org/PathwayBrowser/#/R-GGA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Gallus gallus 65049 R-GGA-200718 https://reactome.org/PathwayBrowser/#/R-GGA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Gallus gallus 65049 R-GGA-200740 https://reactome.org/PathwayBrowser/#/R-GGA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Gallus gallus 65049 R-GGA-6801342 https://reactome.org/PathwayBrowser/#/R-GGA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Gallus gallus 65049 R-HSA-200644 https://reactome.org/PathwayBrowser/#/R-HSA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ TAS Homo sapiens 65049 R-HSA-200661 https://reactome.org/PathwayBrowser/#/R-HSA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG TAS Homo sapiens 65049 R-HSA-200718 https://reactome.org/PathwayBrowser/#/R-HSA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG TAS Homo sapiens 65049 R-HSA-200740 https://reactome.org/PathwayBrowser/#/R-HSA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate TAS Homo sapiens 65049 R-HSA-6801342 https://reactome.org/PathwayBrowser/#/R-HSA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG TAS Homo sapiens 65049 R-MMU-200644 https://reactome.org/PathwayBrowser/#/R-MMU-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Mus musculus 65049 R-MMU-200661 https://reactome.org/PathwayBrowser/#/R-MMU-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Mus musculus 65049 R-MMU-200718 https://reactome.org/PathwayBrowser/#/R-MMU-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Mus musculus 65049 R-MMU-200740 https://reactome.org/PathwayBrowser/#/R-MMU-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Mus musculus 65049 R-MMU-6801342 https://reactome.org/PathwayBrowser/#/R-MMU-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Mus musculus 65049 R-PFA-200644 https://reactome.org/PathwayBrowser/#/R-PFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Plasmodium falciparum 65049 R-PFA-200661 https://reactome.org/PathwayBrowser/#/R-PFA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Plasmodium falciparum 65049 R-PFA-200718 https://reactome.org/PathwayBrowser/#/R-PFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Plasmodium falciparum 65049 R-PFA-200740 https://reactome.org/PathwayBrowser/#/R-PFA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Plasmodium falciparum 65049 R-PFA-6801342 https://reactome.org/PathwayBrowser/#/R-PFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Plasmodium falciparum 65049 R-RNO-200644 https://reactome.org/PathwayBrowser/#/R-RNO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Rattus norvegicus 65049 R-RNO-200661 https://reactome.org/PathwayBrowser/#/R-RNO-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Rattus norvegicus 65049 R-RNO-200718 https://reactome.org/PathwayBrowser/#/R-RNO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Rattus norvegicus 65049 R-RNO-200740 https://reactome.org/PathwayBrowser/#/R-RNO-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Rattus norvegicus 65049 R-RNO-6801342 https://reactome.org/PathwayBrowser/#/R-RNO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Rattus norvegicus 65049 R-SCE-200644 https://reactome.org/PathwayBrowser/#/R-SCE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Saccharomyces cerevisiae 65049 R-SCE-200661 https://reactome.org/PathwayBrowser/#/R-SCE-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Saccharomyces cerevisiae 65049 R-SCE-200718 https://reactome.org/PathwayBrowser/#/R-SCE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Saccharomyces cerevisiae 65049 R-SCE-200740 https://reactome.org/PathwayBrowser/#/R-SCE-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Saccharomyces cerevisiae 65049 R-SCE-6801342 https://reactome.org/PathwayBrowser/#/R-SCE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Saccharomyces cerevisiae 65049 R-SPO-200644 https://reactome.org/PathwayBrowser/#/R-SPO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Schizosaccharomyces pombe 65049 R-SPO-200661 https://reactome.org/PathwayBrowser/#/R-SPO-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Schizosaccharomyces pombe 65049 R-SPO-200718 https://reactome.org/PathwayBrowser/#/R-SPO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Schizosaccharomyces pombe 65049 R-SPO-200740 https://reactome.org/PathwayBrowser/#/R-SPO-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Schizosaccharomyces pombe 65049 R-SPO-6801342 https://reactome.org/PathwayBrowser/#/R-SPO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Schizosaccharomyces pombe 65049 R-SSC-200644 https://reactome.org/PathwayBrowser/#/R-SSC-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Sus scrofa 65049 R-SSC-200661 https://reactome.org/PathwayBrowser/#/R-SSC-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Sus scrofa 65049 R-SSC-200718 https://reactome.org/PathwayBrowser/#/R-SSC-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Sus scrofa 65049 R-SSC-200740 https://reactome.org/PathwayBrowser/#/R-SSC-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Sus scrofa 65049 R-SSC-6801342 https://reactome.org/PathwayBrowser/#/R-SSC-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Sus scrofa 65049 R-XTR-200644 https://reactome.org/PathwayBrowser/#/R-XTR-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Xenopus tropicalis 65049 R-XTR-200661 https://reactome.org/PathwayBrowser/#/R-XTR-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Xenopus tropicalis 65049 R-XTR-200718 https://reactome.org/PathwayBrowser/#/R-XTR-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Xenopus tropicalis 65049 R-XTR-200740 https://reactome.org/PathwayBrowser/#/R-XTR-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Xenopus tropicalis 65049 R-XTR-6801342 https://reactome.org/PathwayBrowser/#/R-XTR-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Xenopus tropicalis 65052 R-BTA-390250 https://reactome.org/PathwayBrowser/#/R-BTA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Bos taurus 65052 R-CFA-390250 https://reactome.org/PathwayBrowser/#/R-CFA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Canis familiaris 65052 R-DDI-390250 https://reactome.org/PathwayBrowser/#/R-DDI-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Dictyostelium discoideum 65052 R-DRE-390250 https://reactome.org/PathwayBrowser/#/R-DRE-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Danio rerio 65052 R-GGA-390250 https://reactome.org/PathwayBrowser/#/R-GGA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Gallus gallus 65052 R-HSA-390250 https://reactome.org/PathwayBrowser/#/R-HSA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA TAS Homo sapiens 65052 R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA TAS Homo sapiens 65052 R-HSA-548830 https://reactome.org/PathwayBrowser/#/R-HSA-548830 ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA IEA Homo sapiens 65052 R-MMU-390250 https://reactome.org/PathwayBrowser/#/R-MMU-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Mus musculus 65052 R-MMU-548848 https://reactome.org/PathwayBrowser/#/R-MMU-548848 lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4] TAS Mus musculus 65052 R-RNO-390250 https://reactome.org/PathwayBrowser/#/R-RNO-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Rattus norvegicus 65052 R-SCE-390250 https://reactome.org/PathwayBrowser/#/R-SCE-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Saccharomyces cerevisiae 65052 R-SSC-390250 https://reactome.org/PathwayBrowser/#/R-SSC-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Sus scrofa 65052 R-XTR-390250 https://reactome.org/PathwayBrowser/#/R-XTR-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Xenopus tropicalis 65088 R-BTA-5695989 https://reactome.org/PathwayBrowser/#/R-BTA-5695989 ACAD11 dehydrogenates BH-CoA IEA Bos taurus 65088 R-CFA-5695989 https://reactome.org/PathwayBrowser/#/R-CFA-5695989 ACAD11 dehydrogenates BH-CoA IEA Canis familiaris 65088 R-DRE-5695989 https://reactome.org/PathwayBrowser/#/R-DRE-5695989 ACAD11 dehydrogenates BH-CoA IEA Danio rerio 65088 R-GGA-5695989 https://reactome.org/PathwayBrowser/#/R-GGA-5695989 ACAD11 dehydrogenates BH-CoA IEA Gallus gallus 65088 R-HSA-5695989 https://reactome.org/PathwayBrowser/#/R-HSA-5695989 ACAD11 dehydrogenates BH-CoA TAS Homo sapiens 65088 R-MMU-5695989 https://reactome.org/PathwayBrowser/#/R-MMU-5695989 ACAD11 dehydrogenates BH-CoA IEA Mus musculus 65088 R-RNO-5695989 https://reactome.org/PathwayBrowser/#/R-RNO-5695989 ACAD11 dehydrogenates BH-CoA IEA Rattus norvegicus 65088 R-SSC-5695989 https://reactome.org/PathwayBrowser/#/R-SSC-5695989 ACAD11 dehydrogenates BH-CoA IEA Sus scrofa 65088 R-XTR-5695989 https://reactome.org/PathwayBrowser/#/R-XTR-5695989 ACAD11 dehydrogenates BH-CoA IEA Xenopus tropicalis 65101 R-BTA-6787811 https://reactome.org/PathwayBrowser/#/R-BTA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Bos taurus 65101 R-CEL-6787811 https://reactome.org/PathwayBrowser/#/R-CEL-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Caenorhabditis elegans 65101 R-CFA-6787811 https://reactome.org/PathwayBrowser/#/R-CFA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Canis familiaris 65101 R-DDI-6787811 https://reactome.org/PathwayBrowser/#/R-DDI-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Dictyostelium discoideum 65101 R-DME-6787811 https://reactome.org/PathwayBrowser/#/R-DME-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Drosophila melanogaster 65101 R-GGA-6787811 https://reactome.org/PathwayBrowser/#/R-GGA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Gallus gallus 65101 R-HSA-6787811 https://reactome.org/PathwayBrowser/#/R-HSA-6787811 HAO2 tetramer oxidises 2OH-PALM TAS Homo sapiens 65101 R-MMU-6787811 https://reactome.org/PathwayBrowser/#/R-MMU-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Mus musculus 65101 R-RNO-6787811 https://reactome.org/PathwayBrowser/#/R-RNO-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Rattus norvegicus 65101 R-SSC-6787811 https://reactome.org/PathwayBrowser/#/R-SSC-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Sus scrofa 65101 R-XTR-6787811 https://reactome.org/PathwayBrowser/#/R-XTR-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Xenopus tropicalis 65130 R-BTA-2066778 https://reactome.org/PathwayBrowser/#/R-BTA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Bos taurus 65130 R-BTA-2066780 https://reactome.org/PathwayBrowser/#/R-BTA-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Bos taurus 65130 R-CEL-2066778 https://reactome.org/PathwayBrowser/#/R-CEL-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Caenorhabditis elegans 65130 R-CEL-2066780 https://reactome.org/PathwayBrowser/#/R-CEL-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Caenorhabditis elegans 65130 R-CFA-2066778 https://reactome.org/PathwayBrowser/#/R-CFA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Canis familiaris 65130 R-CFA-2066780 https://reactome.org/PathwayBrowser/#/R-CFA-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Canis familiaris 65130 R-DDI-2066778 https://reactome.org/PathwayBrowser/#/R-DDI-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Dictyostelium discoideum 65130 R-DDI-2066780 https://reactome.org/PathwayBrowser/#/R-DDI-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Dictyostelium discoideum 65130 R-DME-2066778 https://reactome.org/PathwayBrowser/#/R-DME-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Drosophila melanogaster 65130 R-DME-2066780 https://reactome.org/PathwayBrowser/#/R-DME-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Drosophila melanogaster 65130 R-GGA-2066778 https://reactome.org/PathwayBrowser/#/R-GGA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Gallus gallus 65130 R-GGA-2066780 https://reactome.org/PathwayBrowser/#/R-GGA-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Gallus gallus 65130 R-HSA-2066778 https://reactome.org/PathwayBrowser/#/R-HSA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA TAS Homo sapiens 65130 R-HSA-2066780 https://reactome.org/PathwayBrowser/#/R-HSA-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA TAS Homo sapiens 65130 R-MMU-2066778 https://reactome.org/PathwayBrowser/#/R-MMU-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Mus musculus 65130 R-MMU-2066780 https://reactome.org/PathwayBrowser/#/R-MMU-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Mus musculus 65130 R-RNO-2066778 https://reactome.org/PathwayBrowser/#/R-RNO-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Rattus norvegicus 65130 R-RNO-2066780 https://reactome.org/PathwayBrowser/#/R-RNO-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Rattus norvegicus 65131 R-BTA-2066780 https://reactome.org/PathwayBrowser/#/R-BTA-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Bos taurus 65131 R-BTA-2066781 https://reactome.org/PathwayBrowser/#/R-BTA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Bos taurus 65131 R-BTA-2066788 https://reactome.org/PathwayBrowser/#/R-BTA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Bos taurus 65131 R-CEL-2066780 https://reactome.org/PathwayBrowser/#/R-CEL-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Caenorhabditis elegans 65131 R-CFA-2066780 https://reactome.org/PathwayBrowser/#/R-CFA-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Canis familiaris 65131 R-CFA-2066781 https://reactome.org/PathwayBrowser/#/R-CFA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Canis familiaris 65131 R-CFA-2066788 https://reactome.org/PathwayBrowser/#/R-CFA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Canis familiaris 65131 R-DDI-2066780 https://reactome.org/PathwayBrowser/#/R-DDI-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Dictyostelium discoideum 65131 R-DDI-2066788 https://reactome.org/PathwayBrowser/#/R-DDI-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Dictyostelium discoideum 65131 R-DME-2066780 https://reactome.org/PathwayBrowser/#/R-DME-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Drosophila melanogaster 65131 R-DME-2066781 https://reactome.org/PathwayBrowser/#/R-DME-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Drosophila melanogaster 65131 R-DRE-2066781 https://reactome.org/PathwayBrowser/#/R-DRE-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Danio rerio 65131 R-DRE-2066788 https://reactome.org/PathwayBrowser/#/R-DRE-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Danio rerio 65131 R-GGA-2066780 https://reactome.org/PathwayBrowser/#/R-GGA-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Gallus gallus 65131 R-GGA-2066781 https://reactome.org/PathwayBrowser/#/R-GGA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Gallus gallus 65131 R-GGA-2066788 https://reactome.org/PathwayBrowser/#/R-GGA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Gallus gallus 65131 R-HSA-2066780 https://reactome.org/PathwayBrowser/#/R-HSA-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA TAS Homo sapiens 65131 R-HSA-2066781 https://reactome.org/PathwayBrowser/#/R-HSA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) TAS Homo sapiens 65131 R-HSA-2066788 https://reactome.org/PathwayBrowser/#/R-HSA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase TAS Homo sapiens 65131 R-MMU-2066780 https://reactome.org/PathwayBrowser/#/R-MMU-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Mus musculus 65131 R-MMU-2066781 https://reactome.org/PathwayBrowser/#/R-MMU-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Mus musculus 65131 R-MMU-2066788 https://reactome.org/PathwayBrowser/#/R-MMU-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Mus musculus 65131 R-RNO-2066780 https://reactome.org/PathwayBrowser/#/R-RNO-2066780 Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA IEA Rattus norvegicus 65131 R-RNO-2066781 https://reactome.org/PathwayBrowser/#/R-RNO-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Rattus norvegicus 65131 R-RNO-2066788 https://reactome.org/PathwayBrowser/#/R-RNO-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Rattus norvegicus 65131 R-SCE-2066788 https://reactome.org/PathwayBrowser/#/R-SCE-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Saccharomyces cerevisiae 65131 R-SSC-2066788 https://reactome.org/PathwayBrowser/#/R-SSC-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Sus scrofa 65131 R-XTR-2066788 https://reactome.org/PathwayBrowser/#/R-XTR-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Xenopus tropicalis 65132 R-BTA-2066779 https://reactome.org/PathwayBrowser/#/R-BTA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Bos taurus 65132 R-BTA-2066781 https://reactome.org/PathwayBrowser/#/R-BTA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Bos taurus 65132 R-BTA-2066788 https://reactome.org/PathwayBrowser/#/R-BTA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Bos taurus 65132 R-CEL-2066779 https://reactome.org/PathwayBrowser/#/R-CEL-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Caenorhabditis elegans 65132 R-CFA-2066779 https://reactome.org/PathwayBrowser/#/R-CFA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Canis familiaris 65132 R-CFA-2066781 https://reactome.org/PathwayBrowser/#/R-CFA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Canis familiaris 65132 R-CFA-2066788 https://reactome.org/PathwayBrowser/#/R-CFA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Canis familiaris 65132 R-DDI-2066788 https://reactome.org/PathwayBrowser/#/R-DDI-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Dictyostelium discoideum 65132 R-DME-2066781 https://reactome.org/PathwayBrowser/#/R-DME-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Drosophila melanogaster 65132 R-DRE-2066779 https://reactome.org/PathwayBrowser/#/R-DRE-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Danio rerio 65132 R-DRE-2066781 https://reactome.org/PathwayBrowser/#/R-DRE-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Danio rerio 65132 R-DRE-2066788 https://reactome.org/PathwayBrowser/#/R-DRE-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Danio rerio 65132 R-GGA-2066779 https://reactome.org/PathwayBrowser/#/R-GGA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Gallus gallus 65132 R-GGA-2066781 https://reactome.org/PathwayBrowser/#/R-GGA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Gallus gallus 65132 R-GGA-2066788 https://reactome.org/PathwayBrowser/#/R-GGA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Gallus gallus 65132 R-HSA-2066779 https://reactome.org/PathwayBrowser/#/R-HSA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) TAS Homo sapiens 65132 R-HSA-2066781 https://reactome.org/PathwayBrowser/#/R-HSA-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) TAS Homo sapiens 65132 R-HSA-2066788 https://reactome.org/PathwayBrowser/#/R-HSA-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase TAS Homo sapiens 65132 R-MMU-2066779 https://reactome.org/PathwayBrowser/#/R-MMU-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Mus musculus 65132 R-MMU-2066781 https://reactome.org/PathwayBrowser/#/R-MMU-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Mus musculus 65132 R-MMU-2066788 https://reactome.org/PathwayBrowser/#/R-MMU-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Mus musculus 65132 R-RNO-2066779 https://reactome.org/PathwayBrowser/#/R-RNO-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Rattus norvegicus 65132 R-RNO-2066781 https://reactome.org/PathwayBrowser/#/R-RNO-2066781 Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) IEA Rattus norvegicus 65132 R-RNO-2066788 https://reactome.org/PathwayBrowser/#/R-RNO-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Rattus norvegicus 65132 R-SCE-2066779 https://reactome.org/PathwayBrowser/#/R-SCE-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Saccharomyces cerevisiae 65132 R-SCE-2066788 https://reactome.org/PathwayBrowser/#/R-SCE-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Saccharomyces cerevisiae 65132 R-SSC-2066779 https://reactome.org/PathwayBrowser/#/R-SSC-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Sus scrofa 65132 R-SSC-2066788 https://reactome.org/PathwayBrowser/#/R-SSC-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Sus scrofa 65132 R-XTR-2066779 https://reactome.org/PathwayBrowser/#/R-XTR-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Xenopus tropicalis 65132 R-XTR-2066788 https://reactome.org/PathwayBrowser/#/R-XTR-2066788 Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase IEA Xenopus tropicalis 65133 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 65133 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 65133 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 65133 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 65133 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 65133 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 65133 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 65133 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 65133 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 65133 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 65133 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 65133 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 65133 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 65133 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 65133 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 65133 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 65133 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 65133 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 65133 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 65133 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 65133 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 65133 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 65133 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 65133 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 65133 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 65133 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 65133 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 65133 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 65133 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 65133 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 65133 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 65133 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 65133 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 65133 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 65133 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 65133 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 65133 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 65133 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 65133 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 65133 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 65133 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 65133 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 65133 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 65133 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 65136 R-BTA-9025152 https://reactome.org/PathwayBrowser/#/R-BTA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Bos taurus 65136 R-BTA-9025957 https://reactome.org/PathwayBrowser/#/R-BTA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Bos taurus 65136 R-CFA-9025152 https://reactome.org/PathwayBrowser/#/R-CFA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Canis familiaris 65136 R-CFA-9025957 https://reactome.org/PathwayBrowser/#/R-CFA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Canis familiaris 65136 R-DDI-9025152 https://reactome.org/PathwayBrowser/#/R-DDI-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Dictyostelium discoideum 65136 R-DDI-9025957 https://reactome.org/PathwayBrowser/#/R-DDI-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Dictyostelium discoideum 65136 R-DRE-9025152 https://reactome.org/PathwayBrowser/#/R-DRE-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Danio rerio 65136 R-DRE-9025957 https://reactome.org/PathwayBrowser/#/R-DRE-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Danio rerio 65136 R-HSA-2046101 https://reactome.org/PathwayBrowser/#/R-HSA-2046101 Peroxisomal beta-oxidation of tetracosapentaenoyl-CoA to Docosapentaenoyl-CoA TAS Homo sapiens 65136 R-HSA-2066782 https://reactome.org/PathwayBrowser/#/R-HSA-2066782 Translocation of DPA to the ER TAS Homo sapiens 65136 R-HSA-9025152 https://reactome.org/PathwayBrowser/#/R-HSA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 TAS Homo sapiens 65136 R-HSA-9025957 https://reactome.org/PathwayBrowser/#/R-HSA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 TAS Homo sapiens 65136 R-MMU-9025152 https://reactome.org/PathwayBrowser/#/R-MMU-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Mus musculus 65136 R-MMU-9025957 https://reactome.org/PathwayBrowser/#/R-MMU-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Mus musculus 65136 R-RNO-9025152 https://reactome.org/PathwayBrowser/#/R-RNO-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Rattus norvegicus 65136 R-RNO-9025957 https://reactome.org/PathwayBrowser/#/R-RNO-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Rattus norvegicus 65136 R-SSC-9025152 https://reactome.org/PathwayBrowser/#/R-SSC-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Sus scrofa 65136 R-SSC-9025957 https://reactome.org/PathwayBrowser/#/R-SSC-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Sus scrofa 65137 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 65137 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 65137 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 65137 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 65137 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 65138 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 65138 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 65138 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 65139 R-BTA-2066778 https://reactome.org/PathwayBrowser/#/R-BTA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Bos taurus 65139 R-BTA-2066787 https://reactome.org/PathwayBrowser/#/R-BTA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Bos taurus 65139 R-CEL-2066778 https://reactome.org/PathwayBrowser/#/R-CEL-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Caenorhabditis elegans 65139 R-CEL-2066787 https://reactome.org/PathwayBrowser/#/R-CEL-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Caenorhabditis elegans 65139 R-CFA-2066778 https://reactome.org/PathwayBrowser/#/R-CFA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Canis familiaris 65139 R-CFA-2066787 https://reactome.org/PathwayBrowser/#/R-CFA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Canis familiaris 65139 R-DDI-2066778 https://reactome.org/PathwayBrowser/#/R-DDI-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Dictyostelium discoideum 65139 R-DDI-2066787 https://reactome.org/PathwayBrowser/#/R-DDI-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Dictyostelium discoideum 65139 R-DME-2066778 https://reactome.org/PathwayBrowser/#/R-DME-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Drosophila melanogaster 65139 R-DME-2066787 https://reactome.org/PathwayBrowser/#/R-DME-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Drosophila melanogaster 65139 R-DRE-2066787 https://reactome.org/PathwayBrowser/#/R-DRE-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Danio rerio 65139 R-GGA-2066778 https://reactome.org/PathwayBrowser/#/R-GGA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Gallus gallus 65139 R-GGA-2066787 https://reactome.org/PathwayBrowser/#/R-GGA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Gallus gallus 65139 R-HSA-2066778 https://reactome.org/PathwayBrowser/#/R-HSA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA TAS Homo sapiens 65139 R-HSA-2066787 https://reactome.org/PathwayBrowser/#/R-HSA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA TAS Homo sapiens 65139 R-MMU-2066778 https://reactome.org/PathwayBrowser/#/R-MMU-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Mus musculus 65139 R-MMU-2066787 https://reactome.org/PathwayBrowser/#/R-MMU-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Mus musculus 65139 R-RNO-2066778 https://reactome.org/PathwayBrowser/#/R-RNO-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Rattus norvegicus 65139 R-RNO-2066787 https://reactome.org/PathwayBrowser/#/R-RNO-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Rattus norvegicus 65139 R-SSC-2066787 https://reactome.org/PathwayBrowser/#/R-SSC-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Sus scrofa 65139 R-XTR-2066787 https://reactome.org/PathwayBrowser/#/R-XTR-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Xenopus tropicalis 65173 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 65173 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 65173 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 65173 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 65173 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 65173 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 65173 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 65173 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 65173 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 65173 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 65310 R-HSA-2400010 https://reactome.org/PathwayBrowser/#/R-HSA-2400010 AKT inhibitors block AKT membrane recruitment TAS Homo sapiens 65314 R-HSA-6782381 https://reactome.org/PathwayBrowser/#/R-HSA-6782381 PUS1 isoform 2 transforms uridine residues to pseudouridine in the anticodon stems of tRNAs IEA Homo sapiens 65314 R-HSA-6786583 https://reactome.org/PathwayBrowser/#/R-HSA-6786583 PUS7 transforms uridine to pseudouridine in tRNAs IEA Homo sapiens 65314 R-HSA-6787566 https://reactome.org/PathwayBrowser/#/R-HSA-6787566 PUS1 isoform 1 transforms uridine-27, uridine-28 yielding pseudouridine in tRNA(Lys,Ser) TAS Homo sapiens 65314 R-HSA-6790905 https://reactome.org/PathwayBrowser/#/R-HSA-6790905 Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA TAS Homo sapiens 65314 R-HSA-6790906 https://reactome.org/PathwayBrowser/#/R-HSA-6790906 EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 IEA Homo sapiens 65314 R-HSA-8870289 https://reactome.org/PathwayBrowser/#/R-HSA-8870289 PUS3 transforms uridine-39 to pseudouridine-39 in tRNA TAS Homo sapiens 65314 R-SCE-6786558 https://reactome.org/PathwayBrowser/#/R-SCE-6786558 PUS7 transforms uridine to pseudouridine at nucleotide 13 of tRNA TAS Saccharomyces cerevisiae 65314 R-SCE-6790166 https://reactome.org/PathwayBrowser/#/R-SCE-6790166 PUS1 transforms uridine residues to pseudouridine in unspliced tRNA(Ile,Tyr) TAS Saccharomyces cerevisiae 65314 R-SCE-6790936 https://reactome.org/PathwayBrowser/#/R-SCE-6790936 EMG1 of the SSU processome methylates pseudouridine-1191 of 18S rRNA yielding N(1)-methylpseudouridine-1191 TAS Saccharomyces cerevisiae 6532 R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 6532 R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 6532 R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 6532 R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 6532 R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 6532 R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 6532 R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 6532 R-SSC-211948 https://reactome.org/PathwayBrowser/#/R-SSC-211948 CYP3A4 can N-demethylate loperamide IEA Sus scrofa 6532 R-XTR-211948 https://reactome.org/PathwayBrowser/#/R-XTR-211948 CYP3A4 can N-demethylate loperamide IEA Xenopus tropicalis 65324 R-HSA-1218824 https://reactome.org/PathwayBrowser/#/R-HSA-1218824 HSP90 is inactivated by binding to benzaquinoid ansamycins TAS Homo sapiens 65326 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 65329 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 65345 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 65349 R-BTA-9611839 https://reactome.org/PathwayBrowser/#/R-BTA-9611839 β3-agonists bind ADRB3 IEA Bos taurus 65349 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 65349 R-CFA-9611839 https://reactome.org/PathwayBrowser/#/R-CFA-9611839 β3-agonists bind ADRB3 IEA Canis familiaris 65349 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 65349 R-DME-9611839 https://reactome.org/PathwayBrowser/#/R-DME-9611839 β3-agonists bind ADRB3 IEA Drosophila melanogaster 65349 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 65349 R-GGA-9611839 https://reactome.org/PathwayBrowser/#/R-GGA-9611839 β3-agonists bind ADRB3 IEA Gallus gallus 65349 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 65349 R-HSA-9611839 https://reactome.org/PathwayBrowser/#/R-HSA-9611839 β3-agonists bind ADRB3 TAS Homo sapiens 65349 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 65349 R-MMU-9611839 https://reactome.org/PathwayBrowser/#/R-MMU-9611839 β3-agonists bind ADRB3 IEA Mus musculus 65349 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 65349 R-RNO-9611839 https://reactome.org/PathwayBrowser/#/R-RNO-9611839 β3-agonists bind ADRB3 IEA Rattus norvegicus 65349 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 65349 R-SSC-9611839 https://reactome.org/PathwayBrowser/#/R-SSC-9611839 β3-agonists bind ADRB3 IEA Sus scrofa 65349 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 65408 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 65408 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 65408 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 65408 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 65408 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 65408 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 65408 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 65408 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 65408 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 65408 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 65408 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 65408 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 65408 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 65408 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 65408 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 65408 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 65408 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 65408 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 65408 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 65408 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 65408 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 65408 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 65408 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 65408 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 65408 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 65408 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 65408 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 65408 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 65408 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 65408 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 65408 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 65408 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 65408 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 65408 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 65408 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 65408 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 65408 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 65408 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 65408 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 65408 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 65408 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 65408 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 6541 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(34-41) binds to AGTR1 IEA Bos taurus 6541 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGRT1 IEA Bos taurus 6541 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(34-41) binds to AGTR1 IEA Caenorhabditis elegans 6541 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGRT1 IEA Caenorhabditis elegans 6541 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(34-41) binds to AGTR1 IEA Canis familiaris 6541 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGRT1 IEA Canis familiaris 6541 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(34-41) binds to AGTR1 IEA Drosophila melanogaster 6541 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGRT1 IEA Drosophila melanogaster 6541 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(34-41) binds to AGTR1 IEA Danio rerio 6541 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGRT1 IEA Danio rerio 6541 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(34-41) binds to AGTR1 IEA Gallus gallus 6541 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGRT1 IEA Gallus gallus 6541 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(34-41) binds to AGTR1 TAS Homo sapiens 6541 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGRT1 TAS Homo sapiens 6541 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(34-41) binds to AGTR1 IEA Mus musculus 6541 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGRT1 IEA Mus musculus 6541 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(34-41) binds to AGTR1 IEA Rattus norvegicus 6541 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGRT1 IEA Rattus norvegicus 6541 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(34-41) binds to AGTR1 IEA Sus scrofa 6541 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGRT1 IEA Sus scrofa 6619 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 6619 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 6619 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 6619 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 6619 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 6619 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 6619 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 6619 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 6619 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 6619 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 6619 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 6619 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 6619 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 6619 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 6619 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 6619 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 6619 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 6619 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 6619 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 6619 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 66899 R-BTA-9718020 https://reactome.org/PathwayBrowser/#/R-BTA-9718020 PTGFR binds PTGFR agonists IEA Bos taurus 66899 R-CFA-9718020 https://reactome.org/PathwayBrowser/#/R-CFA-9718020 PTGFR binds PTGFR agonists IEA Canis familiaris 66899 R-DME-9718020 https://reactome.org/PathwayBrowser/#/R-DME-9718020 PTGFR binds PTGFR agonists IEA Drosophila melanogaster 66899 R-DRE-9718020 https://reactome.org/PathwayBrowser/#/R-DRE-9718020 PTGFR binds PTGFR agonists IEA Danio rerio 66899 R-GGA-9718020 https://reactome.org/PathwayBrowser/#/R-GGA-9718020 PTGFR binds PTGFR agonists IEA Gallus gallus 66899 R-HSA-9718020 https://reactome.org/PathwayBrowser/#/R-HSA-9718020 PTGFR binds PTGFR agonists TAS Homo sapiens 66899 R-MMU-9718020 https://reactome.org/PathwayBrowser/#/R-MMU-9718020 PTGFR binds PTGFR agonists IEA Mus musculus 66899 R-RNO-9718020 https://reactome.org/PathwayBrowser/#/R-RNO-9718020 PTGFR binds PTGFR agonists IEA Rattus norvegicus 66899 R-SSC-9718020 https://reactome.org/PathwayBrowser/#/R-SSC-9718020 PTGFR binds PTGFR agonists IEA Sus scrofa 66899 R-XTR-9718020 https://reactome.org/PathwayBrowser/#/R-XTR-9718020 PTGFR binds PTGFR agonists IEA Xenopus tropicalis 66901 R-HSA-5678992 https://reactome.org/PathwayBrowser/#/R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region TAS Homo sapiens 66901 R-HSA-5679000 https://reactome.org/PathwayBrowser/#/R-HSA-5679000 Ivacaftor binds CFTR G551D TAS Homo sapiens 66914 R-BTA-1889978 https://reactome.org/PathwayBrowser/#/R-BTA-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Bos taurus 66914 R-BTA-1889981 https://reactome.org/PathwayBrowser/#/R-BTA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Bos taurus 66914 R-BTA-1964501 https://reactome.org/PathwayBrowser/#/R-BTA-1964501 Addition of galactose to Core 6 glycoprotein IEA Bos taurus 66914 R-BTA-1964505 https://reactome.org/PathwayBrowser/#/R-BTA-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Bos taurus 66914 R-BTA-1981120 https://reactome.org/PathwayBrowser/#/R-BTA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Bos taurus 66914 R-BTA-1981128 https://reactome.org/PathwayBrowser/#/R-BTA-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Bos taurus 66914 R-BTA-2025723 https://reactome.org/PathwayBrowser/#/R-BTA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Bos taurus 66914 R-BTA-2046265 https://reactome.org/PathwayBrowser/#/R-BTA-2046265 B4GALTs transfer Gal to the keratan chain IEA Bos taurus 66914 R-BTA-2046298 https://reactome.org/PathwayBrowser/#/R-BTA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Bos taurus 66914 R-BTA-5653878 https://reactome.org/PathwayBrowser/#/R-BTA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Bos taurus 66914 R-BTA-5653886 https://reactome.org/PathwayBrowser/#/R-BTA-5653886 B4GALT1 binds LALBA IEA Bos taurus 66914 R-BTA-6785933 https://reactome.org/PathwayBrowser/#/R-BTA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Bos taurus 66914 R-BTA-70361 https://reactome.org/PathwayBrowser/#/R-BTA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Bos taurus 66914 R-BTA-70369 https://reactome.org/PathwayBrowser/#/R-BTA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Bos taurus 66914 R-BTA-735702 https://reactome.org/PathwayBrowser/#/R-BTA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Bos taurus 66914 R-BTA-8855954 https://reactome.org/PathwayBrowser/#/R-BTA-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Bos taurus 66914 R-BTA-9033961 https://reactome.org/PathwayBrowser/#/R-BTA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Bos taurus 66914 R-BTA-9034053 https://reactome.org/PathwayBrowser/#/R-BTA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Bos taurus 66914 R-BTA-914006 https://reactome.org/PathwayBrowser/#/R-BTA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Bos taurus 66914 R-BTA-9603989 https://reactome.org/PathwayBrowser/#/R-BTA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Bos taurus 66914 R-BTA-975919 https://reactome.org/PathwayBrowser/#/R-BTA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Bos taurus 66914 R-BTA-9845516 https://reactome.org/PathwayBrowser/#/R-BTA-9845516 B3GALT4 transfers Gal to gangliosides IEA Bos taurus 66914 R-BTA-9846477 https://reactome.org/PathwayBrowser/#/R-BTA-9846477 A4GALT transfers galactose to LacCer IEA Bos taurus 66914 R-BTA-9851347 https://reactome.org/PathwayBrowser/#/R-BTA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Bos taurus 66914 R-CEL-1889978 https://reactome.org/PathwayBrowser/#/R-CEL-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Caenorhabditis elegans 66914 R-CEL-1889981 https://reactome.org/PathwayBrowser/#/R-CEL-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Caenorhabditis elegans 66914 R-CEL-1964505 https://reactome.org/PathwayBrowser/#/R-CEL-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Caenorhabditis elegans 66914 R-CEL-1981120 https://reactome.org/PathwayBrowser/#/R-CEL-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Caenorhabditis elegans 66914 R-CEL-1981128 https://reactome.org/PathwayBrowser/#/R-CEL-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Caenorhabditis elegans 66914 R-CEL-6785933 https://reactome.org/PathwayBrowser/#/R-CEL-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Caenorhabditis elegans 66914 R-CEL-70361 https://reactome.org/PathwayBrowser/#/R-CEL-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Caenorhabditis elegans 66914 R-CEL-70369 https://reactome.org/PathwayBrowser/#/R-CEL-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Caenorhabditis elegans 66914 R-CEL-735702 https://reactome.org/PathwayBrowser/#/R-CEL-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Caenorhabditis elegans 66914 R-CEL-914006 https://reactome.org/PathwayBrowser/#/R-CEL-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Caenorhabditis elegans 66914 R-CEL-9603989 https://reactome.org/PathwayBrowser/#/R-CEL-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Caenorhabditis elegans 66914 R-CEL-9845516 https://reactome.org/PathwayBrowser/#/R-CEL-9845516 B3GALT4 transfers Gal to gangliosides IEA Caenorhabditis elegans 66914 R-CFA-1889978 https://reactome.org/PathwayBrowser/#/R-CFA-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Canis familiaris 66914 R-CFA-1889981 https://reactome.org/PathwayBrowser/#/R-CFA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Canis familiaris 66914 R-CFA-1964501 https://reactome.org/PathwayBrowser/#/R-CFA-1964501 Addition of galactose to Core 6 glycoprotein IEA Canis familiaris 66914 R-CFA-1964505 https://reactome.org/PathwayBrowser/#/R-CFA-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Canis familiaris 66914 R-CFA-1981120 https://reactome.org/PathwayBrowser/#/R-CFA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Canis familiaris 66914 R-CFA-1981128 https://reactome.org/PathwayBrowser/#/R-CFA-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Canis familiaris 66914 R-CFA-2025723 https://reactome.org/PathwayBrowser/#/R-CFA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Canis familiaris 66914 R-CFA-2046265 https://reactome.org/PathwayBrowser/#/R-CFA-2046265 B4GALTs transfer Gal to the keratan chain IEA Canis familiaris 66914 R-CFA-2046298 https://reactome.org/PathwayBrowser/#/R-CFA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Canis familiaris 66914 R-CFA-5653878 https://reactome.org/PathwayBrowser/#/R-CFA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Canis familiaris 66914 R-CFA-5653886 https://reactome.org/PathwayBrowser/#/R-CFA-5653886 B4GALT1 binds LALBA IEA Canis familiaris 66914 R-CFA-6785933 https://reactome.org/PathwayBrowser/#/R-CFA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Canis familiaris 66914 R-CFA-70361 https://reactome.org/PathwayBrowser/#/R-CFA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Canis familiaris 66914 R-CFA-70369 https://reactome.org/PathwayBrowser/#/R-CFA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Canis familiaris 66914 R-CFA-735702 https://reactome.org/PathwayBrowser/#/R-CFA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Canis familiaris 66914 R-CFA-8855954 https://reactome.org/PathwayBrowser/#/R-CFA-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Canis familiaris 66914 R-CFA-9033961 https://reactome.org/PathwayBrowser/#/R-CFA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Canis familiaris 66914 R-CFA-9034053 https://reactome.org/PathwayBrowser/#/R-CFA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Canis familiaris 66914 R-CFA-914006 https://reactome.org/PathwayBrowser/#/R-CFA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Canis familiaris 66914 R-CFA-9603989 https://reactome.org/PathwayBrowser/#/R-CFA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Canis familiaris 66914 R-CFA-975919 https://reactome.org/PathwayBrowser/#/R-CFA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Canis familiaris 66914 R-CFA-9845516 https://reactome.org/PathwayBrowser/#/R-CFA-9845516 B3GALT4 transfers Gal to gangliosides IEA Canis familiaris 66914 R-CFA-9846477 https://reactome.org/PathwayBrowser/#/R-CFA-9846477 A4GALT transfers galactose to LacCer IEA Canis familiaris 66914 R-CFA-9851347 https://reactome.org/PathwayBrowser/#/R-CFA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Canis familiaris 66914 R-CGR-2032355 https://reactome.org/PathwayBrowser/#/R-CGR-2032355 Galactosylation of Pre-Notch TAS Cricetulus griseus 66914 R-DDI-70369 https://reactome.org/PathwayBrowser/#/R-DDI-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Dictyostelium discoideum 66914 R-DDI-914006 https://reactome.org/PathwayBrowser/#/R-DDI-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Dictyostelium discoideum 66914 R-DME-1889978 https://reactome.org/PathwayBrowser/#/R-DME-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Drosophila melanogaster 66914 R-DME-1889981 https://reactome.org/PathwayBrowser/#/R-DME-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Drosophila melanogaster 66914 R-DME-1964501 https://reactome.org/PathwayBrowser/#/R-DME-1964501 Addition of galactose to Core 6 glycoprotein IEA Drosophila melanogaster 66914 R-DME-1964505 https://reactome.org/PathwayBrowser/#/R-DME-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Drosophila melanogaster 66914 R-DME-1981120 https://reactome.org/PathwayBrowser/#/R-DME-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Drosophila melanogaster 66914 R-DME-1981128 https://reactome.org/PathwayBrowser/#/R-DME-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Drosophila melanogaster 66914 R-DME-2025723 https://reactome.org/PathwayBrowser/#/R-DME-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Drosophila melanogaster 66914 R-DME-2046265 https://reactome.org/PathwayBrowser/#/R-DME-2046265 B4GALTs transfer Gal to the keratan chain IEA Drosophila melanogaster 66914 R-DME-2046298 https://reactome.org/PathwayBrowser/#/R-DME-2046298 B4GALTs transfer Gal to a branch of keratan IEA Drosophila melanogaster 66914 R-DME-5653878 https://reactome.org/PathwayBrowser/#/R-DME-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Drosophila melanogaster 66914 R-DME-5653886 https://reactome.org/PathwayBrowser/#/R-DME-5653886 B4GALT1 binds LALBA IEA Drosophila melanogaster 66914 R-DME-70361 https://reactome.org/PathwayBrowser/#/R-DME-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Drosophila melanogaster 66914 R-DME-70369 https://reactome.org/PathwayBrowser/#/R-DME-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Drosophila melanogaster 66914 R-DME-735702 https://reactome.org/PathwayBrowser/#/R-DME-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Drosophila melanogaster 66914 R-DME-914006 https://reactome.org/PathwayBrowser/#/R-DME-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Drosophila melanogaster 66914 R-DME-9603989 https://reactome.org/PathwayBrowser/#/R-DME-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Drosophila melanogaster 66914 R-DME-975919 https://reactome.org/PathwayBrowser/#/R-DME-975919 Addition of galactose by beta 4-galactosyltransferases IEA Drosophila melanogaster 66914 R-DME-9845516 https://reactome.org/PathwayBrowser/#/R-DME-9845516 B3GALT4 transfers Gal to gangliosides IEA Drosophila melanogaster 66914 R-DME-9846477 https://reactome.org/PathwayBrowser/#/R-DME-9846477 A4GALT transfers galactose to LacCer IEA Drosophila melanogaster 66914 R-DME-9851347 https://reactome.org/PathwayBrowser/#/R-DME-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Drosophila melanogaster 66914 R-DRE-1889978 https://reactome.org/PathwayBrowser/#/R-DRE-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Danio rerio 66914 R-DRE-1964501 https://reactome.org/PathwayBrowser/#/R-DRE-1964501 Addition of galactose to Core 6 glycoprotein IEA Danio rerio 66914 R-DRE-1981120 https://reactome.org/PathwayBrowser/#/R-DRE-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Danio rerio 66914 R-DRE-1981128 https://reactome.org/PathwayBrowser/#/R-DRE-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Danio rerio 66914 R-DRE-2025723 https://reactome.org/PathwayBrowser/#/R-DRE-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Danio rerio 66914 R-DRE-2046265 https://reactome.org/PathwayBrowser/#/R-DRE-2046265 B4GALTs transfer Gal to the keratan chain IEA Danio rerio 66914 R-DRE-2046298 https://reactome.org/PathwayBrowser/#/R-DRE-2046298 B4GALTs transfer Gal to a branch of keratan IEA Danio rerio 66914 R-DRE-5653878 https://reactome.org/PathwayBrowser/#/R-DRE-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Danio rerio 66914 R-DRE-5653886 https://reactome.org/PathwayBrowser/#/R-DRE-5653886 B4GALT1 binds LALBA IEA Danio rerio 66914 R-DRE-6785933 https://reactome.org/PathwayBrowser/#/R-DRE-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Danio rerio 66914 R-DRE-70369 https://reactome.org/PathwayBrowser/#/R-DRE-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Danio rerio 66914 R-DRE-9033961 https://reactome.org/PathwayBrowser/#/R-DRE-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Danio rerio 66914 R-DRE-9034053 https://reactome.org/PathwayBrowser/#/R-DRE-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Danio rerio 66914 R-DRE-914006 https://reactome.org/PathwayBrowser/#/R-DRE-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Danio rerio 66914 R-DRE-9603989 https://reactome.org/PathwayBrowser/#/R-DRE-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Danio rerio 66914 R-DRE-975919 https://reactome.org/PathwayBrowser/#/R-DRE-975919 Addition of galactose by beta 4-galactosyltransferases IEA Danio rerio 66914 R-DRE-9851347 https://reactome.org/PathwayBrowser/#/R-DRE-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Danio rerio 66914 R-GGA-1889981 https://reactome.org/PathwayBrowser/#/R-GGA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Gallus gallus 66914 R-GGA-1964501 https://reactome.org/PathwayBrowser/#/R-GGA-1964501 Addition of galactose to Core 6 glycoprotein IEA Gallus gallus 66914 R-GGA-1964505 https://reactome.org/PathwayBrowser/#/R-GGA-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Gallus gallus 66914 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Gallus gallus 66914 R-GGA-2025723 https://reactome.org/PathwayBrowser/#/R-GGA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Gallus gallus 66914 R-GGA-2046265 https://reactome.org/PathwayBrowser/#/R-GGA-2046265 B4GALTs transfer Gal to the keratan chain IEA Gallus gallus 66914 R-GGA-2046298 https://reactome.org/PathwayBrowser/#/R-GGA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Gallus gallus 66914 R-GGA-5653878 https://reactome.org/PathwayBrowser/#/R-GGA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Gallus gallus 66914 R-GGA-5653886 https://reactome.org/PathwayBrowser/#/R-GGA-5653886 B4GALT1 binds LALBA IEA Gallus gallus 66914 R-GGA-6785933 https://reactome.org/PathwayBrowser/#/R-GGA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Gallus gallus 66914 R-GGA-70369 https://reactome.org/PathwayBrowser/#/R-GGA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Gallus gallus 66914 R-GGA-914006 https://reactome.org/PathwayBrowser/#/R-GGA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Gallus gallus 66914 R-GGA-9603989 https://reactome.org/PathwayBrowser/#/R-GGA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Gallus gallus 66914 R-GGA-975919 https://reactome.org/PathwayBrowser/#/R-GGA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Gallus gallus 66914 R-GGA-9846477 https://reactome.org/PathwayBrowser/#/R-GGA-9846477 A4GALT transfers galactose to LacCer IEA Gallus gallus 66914 R-GGA-9851347 https://reactome.org/PathwayBrowser/#/R-GGA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Gallus gallus 66914 R-HSA-1889978 https://reactome.org/PathwayBrowser/#/R-HSA-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker TAS Homo sapiens 66914 R-HSA-1889981 https://reactome.org/PathwayBrowser/#/R-HSA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker TAS Homo sapiens 66914 R-HSA-1912352 https://reactome.org/PathwayBrowser/#/R-HSA-1912352 Galactosylation of Pre-NOTCH IEA Homo sapiens 66914 R-HSA-1964501 https://reactome.org/PathwayBrowser/#/R-HSA-1964501 Addition of galactose to Core 6 glycoprotein TAS Homo sapiens 66914 R-HSA-1964505 https://reactome.org/PathwayBrowser/#/R-HSA-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) TAS Homo sapiens 66914 R-HSA-1981120 https://reactome.org/PathwayBrowser/#/R-HSA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. TAS Homo sapiens 66914 R-HSA-1981128 https://reactome.org/PathwayBrowser/#/R-HSA-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 TAS Homo sapiens 66914 R-HSA-2025723 https://reactome.org/PathwayBrowser/#/R-HSA-2025723 B4GALTs transfer Gal to the N-glycan precursor TAS Homo sapiens 66914 R-HSA-2046265 https://reactome.org/PathwayBrowser/#/R-HSA-2046265 B4GALTs transfer Gal to the keratan chain TAS Homo sapiens 66914 R-HSA-2046298 https://reactome.org/PathwayBrowser/#/R-HSA-2046298 B4GALTs transfer Gal to a branch of keratan TAS Homo sapiens 66914 R-HSA-3560804 https://reactome.org/PathwayBrowser/#/R-HSA-3560804 Defective B4GALT7 does not transfer Gal to xylosyl-unit of the tetrasaccharide linker TAS Homo sapiens 66914 R-HSA-3656230 https://reactome.org/PathwayBrowser/#/R-HSA-3656230 Defective B4GALT1 does not transfer Gal to the keratan chain TAS Homo sapiens 66914 R-HSA-4420365 https://reactome.org/PathwayBrowser/#/R-HSA-4420365 Defective B3GALT6 does not transfer Gal to the tetrasaccharide linker TAS Homo sapiens 66914 R-HSA-4793956 https://reactome.org/PathwayBrowser/#/R-HSA-4793956 Defective B4GALT1 does not add Gal to N-glycan TAS Homo sapiens 66914 R-HSA-5610036 https://reactome.org/PathwayBrowser/#/R-HSA-5610036 Defective GALE does not epimerise UDP-Gal to UDP-Glc TAS Homo sapiens 66914 R-HSA-5652099 https://reactome.org/PathwayBrowser/#/R-HSA-5652099 Defective SLC35A2 does not exchange UDP-Gal, UDP-GalNAc for UMP TAS Homo sapiens 66914 R-HSA-5653878 https://reactome.org/PathwayBrowser/#/R-HSA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac TAS Homo sapiens 66914 R-HSA-5653886 https://reactome.org/PathwayBrowser/#/R-HSA-5653886 B4GALT1 binds LALBA TAS Homo sapiens 66914 R-HSA-6785524 https://reactome.org/PathwayBrowser/#/R-HSA-6785524 Defective C1GALT1C1 does not bind C1GALT1 TAS Homo sapiens 66914 R-HSA-6785933 https://reactome.org/PathwayBrowser/#/R-HSA-6785933 UGT8 transfers Gal from UDP-Gal to CERA TAS Homo sapiens 66914 R-HSA-70361 https://reactome.org/PathwayBrowser/#/R-HSA-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal TAS Homo sapiens 66914 R-HSA-70369 https://reactome.org/PathwayBrowser/#/R-HSA-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc TAS Homo sapiens 66914 R-HSA-735702 https://reactome.org/PathwayBrowser/#/R-HSA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP TAS Homo sapiens 66914 R-HSA-8855954 https://reactome.org/PathwayBrowser/#/R-HSA-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD TAS Homo sapiens 66914 R-HSA-9033961 https://reactome.org/PathwayBrowser/#/R-HSA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC TAS Homo sapiens 66914 R-HSA-9034053 https://reactome.org/PathwayBrowser/#/R-HSA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen TAS Homo sapiens 66914 R-HSA-9035949 https://reactome.org/PathwayBrowser/#/R-HSA-9035949 Defective B4GALT1 does not transfer Gal to the N-glycan precursor TAS Homo sapiens 66914 R-HSA-9035950 https://reactome.org/PathwayBrowser/#/R-HSA-9035950 Defective B4GALT1 does not transfer Gal to a branch of keratan TAS Homo sapiens 66914 R-HSA-914006 https://reactome.org/PathwayBrowser/#/R-HSA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein TAS Homo sapiens 66914 R-HSA-9603989 https://reactome.org/PathwayBrowser/#/R-HSA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain TAS Homo sapiens 66914 R-HSA-975919 https://reactome.org/PathwayBrowser/#/R-HSA-975919 Addition of galactose by beta 4-galactosyltransferases TAS Homo sapiens 66914 R-HSA-9845516 https://reactome.org/PathwayBrowser/#/R-HSA-9845516 B3GALT4 transfers Gal to gangliosides TAS Homo sapiens 66914 R-HSA-9846477 https://reactome.org/PathwayBrowser/#/R-HSA-9846477 A4GALT transfers galactose to LacCer TAS Homo sapiens 66914 R-HSA-9851347 https://reactome.org/PathwayBrowser/#/R-HSA-9851347 B4GALT5/6 transfer Gal to GlcCer TAS Homo sapiens 66914 R-MMU-1889978 https://reactome.org/PathwayBrowser/#/R-MMU-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Mus musculus 66914 R-MMU-1889981 https://reactome.org/PathwayBrowser/#/R-MMU-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Mus musculus 66914 R-MMU-1964501 https://reactome.org/PathwayBrowser/#/R-MMU-1964501 Addition of galactose to Core 6 glycoprotein IEA Mus musculus 66914 R-MMU-1964505 https://reactome.org/PathwayBrowser/#/R-MMU-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Mus musculus 66914 R-MMU-1981120 https://reactome.org/PathwayBrowser/#/R-MMU-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Mus musculus 66914 R-MMU-1981128 https://reactome.org/PathwayBrowser/#/R-MMU-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Mus musculus 66914 R-MMU-2025723 https://reactome.org/PathwayBrowser/#/R-MMU-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Mus musculus 66914 R-MMU-2046265 https://reactome.org/PathwayBrowser/#/R-MMU-2046265 B4GALTs transfer Gal to the keratan chain IEA Mus musculus 66914 R-MMU-2046298 https://reactome.org/PathwayBrowser/#/R-MMU-2046298 B4GALTs transfer Gal to a branch of keratan IEA Mus musculus 66914 R-MMU-5653878 https://reactome.org/PathwayBrowser/#/R-MMU-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Mus musculus 66914 R-MMU-5653886 https://reactome.org/PathwayBrowser/#/R-MMU-5653886 B4GALT1 binds LALBA IEA Mus musculus 66914 R-MMU-6785933 https://reactome.org/PathwayBrowser/#/R-MMU-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Mus musculus 66914 R-MMU-70361 https://reactome.org/PathwayBrowser/#/R-MMU-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Mus musculus 66914 R-MMU-70369 https://reactome.org/PathwayBrowser/#/R-MMU-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Mus musculus 66914 R-MMU-735702 https://reactome.org/PathwayBrowser/#/R-MMU-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Mus musculus 66914 R-MMU-8855954 https://reactome.org/PathwayBrowser/#/R-MMU-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Mus musculus 66914 R-MMU-9033961 https://reactome.org/PathwayBrowser/#/R-MMU-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Mus musculus 66914 R-MMU-9034053 https://reactome.org/PathwayBrowser/#/R-MMU-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Mus musculus 66914 R-MMU-914006 https://reactome.org/PathwayBrowser/#/R-MMU-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Mus musculus 66914 R-MMU-9603989 https://reactome.org/PathwayBrowser/#/R-MMU-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Mus musculus 66914 R-MMU-975919 https://reactome.org/PathwayBrowser/#/R-MMU-975919 Addition of galactose by beta 4-galactosyltransferases IEA Mus musculus 66914 R-MMU-9845516 https://reactome.org/PathwayBrowser/#/R-MMU-9845516 B3GALT4 transfers Gal to gangliosides IEA Mus musculus 66914 R-MMU-9846477 https://reactome.org/PathwayBrowser/#/R-MMU-9846477 A4GALT transfers galactose to LacCer IEA Mus musculus 66914 R-MMU-9851347 https://reactome.org/PathwayBrowser/#/R-MMU-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Mus musculus 66914 R-PFA-735702 https://reactome.org/PathwayBrowser/#/R-PFA-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Plasmodium falciparum 66914 R-PFA-914006 https://reactome.org/PathwayBrowser/#/R-PFA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Plasmodium falciparum 66914 R-RNO-1889978 https://reactome.org/PathwayBrowser/#/R-RNO-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Rattus norvegicus 66914 R-RNO-1889981 https://reactome.org/PathwayBrowser/#/R-RNO-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Rattus norvegicus 66914 R-RNO-1964501 https://reactome.org/PathwayBrowser/#/R-RNO-1964501 Addition of galactose to Core 6 glycoprotein IEA Rattus norvegicus 66914 R-RNO-1964505 https://reactome.org/PathwayBrowser/#/R-RNO-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Rattus norvegicus 66914 R-RNO-1981120 https://reactome.org/PathwayBrowser/#/R-RNO-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Rattus norvegicus 66914 R-RNO-1981128 https://reactome.org/PathwayBrowser/#/R-RNO-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Rattus norvegicus 66914 R-RNO-2025723 https://reactome.org/PathwayBrowser/#/R-RNO-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Rattus norvegicus 66914 R-RNO-2046265 https://reactome.org/PathwayBrowser/#/R-RNO-2046265 B4GALTs transfer Gal to the keratan chain IEA Rattus norvegicus 66914 R-RNO-2046298 https://reactome.org/PathwayBrowser/#/R-RNO-2046298 B4GALTs transfer Gal to a branch of keratan IEA Rattus norvegicus 66914 R-RNO-6785933 https://reactome.org/PathwayBrowser/#/R-RNO-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Rattus norvegicus 66914 R-RNO-70361 https://reactome.org/PathwayBrowser/#/R-RNO-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Rattus norvegicus 66914 R-RNO-70369 https://reactome.org/PathwayBrowser/#/R-RNO-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Rattus norvegicus 66914 R-RNO-735702 https://reactome.org/PathwayBrowser/#/R-RNO-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Rattus norvegicus 66914 R-RNO-8855954 https://reactome.org/PathwayBrowser/#/R-RNO-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Rattus norvegicus 66914 R-RNO-9033961 https://reactome.org/PathwayBrowser/#/R-RNO-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Rattus norvegicus 66914 R-RNO-9034053 https://reactome.org/PathwayBrowser/#/R-RNO-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Rattus norvegicus 66914 R-RNO-914006 https://reactome.org/PathwayBrowser/#/R-RNO-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Rattus norvegicus 66914 R-RNO-9603989 https://reactome.org/PathwayBrowser/#/R-RNO-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Rattus norvegicus 66914 R-RNO-975919 https://reactome.org/PathwayBrowser/#/R-RNO-975919 Addition of galactose by beta 4-galactosyltransferases IEA Rattus norvegicus 66914 R-RNO-9845516 https://reactome.org/PathwayBrowser/#/R-RNO-9845516 B3GALT4 transfers Gal to gangliosides IEA Rattus norvegicus 66914 R-RNO-9846477 https://reactome.org/PathwayBrowser/#/R-RNO-9846477 A4GALT transfers galactose to LacCer IEA Rattus norvegicus 66914 R-RNO-9851347 https://reactome.org/PathwayBrowser/#/R-RNO-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Rattus norvegicus 66914 R-SCE-70369 https://reactome.org/PathwayBrowser/#/R-SCE-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Saccharomyces cerevisiae 66914 R-SPO-70369 https://reactome.org/PathwayBrowser/#/R-SPO-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Schizosaccharomyces pombe 66914 R-SSC-1889978 https://reactome.org/PathwayBrowser/#/R-SSC-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Sus scrofa 66914 R-SSC-1889981 https://reactome.org/PathwayBrowser/#/R-SSC-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Sus scrofa 66914 R-SSC-1964501 https://reactome.org/PathwayBrowser/#/R-SSC-1964501 Addition of galactose to Core 6 glycoprotein IEA Sus scrofa 66914 R-SSC-1964505 https://reactome.org/PathwayBrowser/#/R-SSC-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Sus scrofa 66914 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Sus scrofa 66914 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa 66914 R-SSC-2025723 https://reactome.org/PathwayBrowser/#/R-SSC-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Sus scrofa 66914 R-SSC-2046265 https://reactome.org/PathwayBrowser/#/R-SSC-2046265 B4GALTs transfer Gal to the keratan chain IEA Sus scrofa 66914 R-SSC-2046298 https://reactome.org/PathwayBrowser/#/R-SSC-2046298 B4GALTs transfer Gal to a branch of keratan IEA Sus scrofa 66914 R-SSC-5653878 https://reactome.org/PathwayBrowser/#/R-SSC-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Sus scrofa 66914 R-SSC-5653886 https://reactome.org/PathwayBrowser/#/R-SSC-5653886 B4GALT1 binds LALBA IEA Sus scrofa 66914 R-SSC-6785933 https://reactome.org/PathwayBrowser/#/R-SSC-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Sus scrofa 66914 R-SSC-70361 https://reactome.org/PathwayBrowser/#/R-SSC-70361 GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal IEA Sus scrofa 66914 R-SSC-70369 https://reactome.org/PathwayBrowser/#/R-SSC-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Sus scrofa 66914 R-SSC-735702 https://reactome.org/PathwayBrowser/#/R-SSC-735702 SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP IEA Sus scrofa 66914 R-SSC-8855954 https://reactome.org/PathwayBrowser/#/R-SSC-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Sus scrofa 66914 R-SSC-914006 https://reactome.org/PathwayBrowser/#/R-SSC-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Sus scrofa 66914 R-SSC-9603989 https://reactome.org/PathwayBrowser/#/R-SSC-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Sus scrofa 66914 R-SSC-975919 https://reactome.org/PathwayBrowser/#/R-SSC-975919 Addition of galactose by beta 4-galactosyltransferases IEA Sus scrofa 66914 R-SSC-9845516 https://reactome.org/PathwayBrowser/#/R-SSC-9845516 B3GALT4 transfers Gal to gangliosides IEA Sus scrofa 66914 R-SSC-9846477 https://reactome.org/PathwayBrowser/#/R-SSC-9846477 A4GALT transfers galactose to LacCer IEA Sus scrofa 66914 R-SSC-9851347 https://reactome.org/PathwayBrowser/#/R-SSC-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Sus scrofa 66914 R-XTR-1889978 https://reactome.org/PathwayBrowser/#/R-XTR-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Xenopus tropicalis 66914 R-XTR-1889981 https://reactome.org/PathwayBrowser/#/R-XTR-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Xenopus tropicalis 66914 R-XTR-1964501 https://reactome.org/PathwayBrowser/#/R-XTR-1964501 Addition of galactose to Core 6 glycoprotein IEA Xenopus tropicalis 66914 R-XTR-1964505 https://reactome.org/PathwayBrowser/#/R-XTR-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Xenopus tropicalis 66914 R-XTR-1981120 https://reactome.org/PathwayBrowser/#/R-XTR-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. IEA Xenopus tropicalis 66914 R-XTR-1981128 https://reactome.org/PathwayBrowser/#/R-XTR-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Xenopus tropicalis 66914 R-XTR-2025723 https://reactome.org/PathwayBrowser/#/R-XTR-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Xenopus tropicalis 66914 R-XTR-2046265 https://reactome.org/PathwayBrowser/#/R-XTR-2046265 B4GALTs transfer Gal to the keratan chain IEA Xenopus tropicalis 66914 R-XTR-2046298 https://reactome.org/PathwayBrowser/#/R-XTR-2046298 B4GALTs transfer Gal to a branch of keratan IEA Xenopus tropicalis 66914 R-XTR-5653878 https://reactome.org/PathwayBrowser/#/R-XTR-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Xenopus tropicalis 66914 R-XTR-5653886 https://reactome.org/PathwayBrowser/#/R-XTR-5653886 B4GALT1 binds LALBA IEA Xenopus tropicalis 66914 R-XTR-70369 https://reactome.org/PathwayBrowser/#/R-XTR-70369 GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc IEA Xenopus tropicalis 66914 R-XTR-8855954 https://reactome.org/PathwayBrowser/#/R-XTR-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD IEA Xenopus tropicalis 66914 R-XTR-9033961 https://reactome.org/PathwayBrowser/#/R-XTR-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Xenopus tropicalis 66914 R-XTR-9034053 https://reactome.org/PathwayBrowser/#/R-XTR-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Xenopus tropicalis 66914 R-XTR-914006 https://reactome.org/PathwayBrowser/#/R-XTR-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Xenopus tropicalis 66914 R-XTR-9603989 https://reactome.org/PathwayBrowser/#/R-XTR-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Xenopus tropicalis 66914 R-XTR-975919 https://reactome.org/PathwayBrowser/#/R-XTR-975919 Addition of galactose by beta 4-galactosyltransferases IEA Xenopus tropicalis 66914 R-XTR-9845516 https://reactome.org/PathwayBrowser/#/R-XTR-9845516 B3GALT4 transfers Gal to gangliosides IEA Xenopus tropicalis 66914 R-XTR-9851347 https://reactome.org/PathwayBrowser/#/R-XTR-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Xenopus tropicalis 67042 R-BTA-8959462 https://reactome.org/PathwayBrowser/#/R-BTA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Bos taurus 67042 R-CEL-8959462 https://reactome.org/PathwayBrowser/#/R-CEL-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Caenorhabditis elegans 67042 R-CFA-8959462 https://reactome.org/PathwayBrowser/#/R-CFA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Canis familiaris 67042 R-DME-8959462 https://reactome.org/PathwayBrowser/#/R-DME-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Drosophila melanogaster 67042 R-DRE-8959462 https://reactome.org/PathwayBrowser/#/R-DRE-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Danio rerio 67042 R-GGA-8959462 https://reactome.org/PathwayBrowser/#/R-GGA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Gallus gallus 67042 R-HSA-8959462 https://reactome.org/PathwayBrowser/#/R-HSA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER TAS Homo sapiens 67042 R-MMU-8959462 https://reactome.org/PathwayBrowser/#/R-MMU-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Mus musculus 67042 R-PFA-8959462 https://reactome.org/PathwayBrowser/#/R-PFA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Plasmodium falciparum 67042 R-RNO-8959462 https://reactome.org/PathwayBrowser/#/R-RNO-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Rattus norvegicus 67042 R-SSC-8959462 https://reactome.org/PathwayBrowser/#/R-SSC-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Sus scrofa 67042 R-XTR-8959462 https://reactome.org/PathwayBrowser/#/R-XTR-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Xenopus tropicalis 67132 R-BTA-4419979 https://reactome.org/PathwayBrowser/#/R-BTA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Bos taurus 67132 R-CEL-4419979 https://reactome.org/PathwayBrowser/#/R-CEL-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Caenorhabditis elegans 67132 R-CFA-4419979 https://reactome.org/PathwayBrowser/#/R-CFA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Canis familiaris 67132 R-DDI-4419979 https://reactome.org/PathwayBrowser/#/R-DDI-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Dictyostelium discoideum 67132 R-DME-4419979 https://reactome.org/PathwayBrowser/#/R-DME-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Drosophila melanogaster 67132 R-DRE-4419979 https://reactome.org/PathwayBrowser/#/R-DRE-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Danio rerio 67132 R-GGA-4419979 https://reactome.org/PathwayBrowser/#/R-GGA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Gallus gallus 67132 R-HSA-4419979 https://reactome.org/PathwayBrowser/#/R-HSA-4419979 SRD5A3 reduces pPNOL to DCHOL TAS Homo sapiens 67132 R-HSA-4419986 https://reactome.org/PathwayBrowser/#/R-HSA-4419986 Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL TAS Homo sapiens 67132 R-HSA-4755572 https://reactome.org/PathwayBrowser/#/R-HSA-4755572 Defective SRD5A3 does not reduce pPNOL to DCHOL TAS Homo sapiens 67132 R-MMU-4419979 https://reactome.org/PathwayBrowser/#/R-MMU-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Mus musculus 67132 R-PFA-4419979 https://reactome.org/PathwayBrowser/#/R-PFA-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Plasmodium falciparum 67132 R-RNO-4419979 https://reactome.org/PathwayBrowser/#/R-RNO-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Rattus norvegicus 67132 R-SCE-4419979 https://reactome.org/PathwayBrowser/#/R-SCE-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Saccharomyces cerevisiae 67132 R-SPO-4419979 https://reactome.org/PathwayBrowser/#/R-SPO-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Schizosaccharomyces pombe 67132 R-SSC-4419979 https://reactome.org/PathwayBrowser/#/R-SSC-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Sus scrofa 67132 R-XTR-4419979 https://reactome.org/PathwayBrowser/#/R-XTR-4419979 SRD5A3 reduces pPNOL to DCHOL IEA Xenopus tropicalis 67208 R-BTA-2106615 https://reactome.org/PathwayBrowser/#/R-BTA-2106615 Removal of siRNA passenger strand IEA Bos taurus 67208 R-BTA-2106625 https://reactome.org/PathwayBrowser/#/R-BTA-2106625 Duplex siRNA is loaded into Argonaute IEA Bos taurus 67208 R-BTA-426464 https://reactome.org/PathwayBrowser/#/R-BTA-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Bos taurus 67208 R-BTA-75090 https://reactome.org/PathwayBrowser/#/R-BTA-75090 Binding of ADAR1 homodimer to dsRNA duplex IEA Bos taurus 67208 R-BTA-77613 https://reactome.org/PathwayBrowser/#/R-BTA-77613 Binding of ADAR2 homodimer to dsRNA duplex IEA Bos taurus 67208 R-BTA-77614 https://reactome.org/PathwayBrowser/#/R-BTA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Bos taurus 67208 R-BTA-77615 https://reactome.org/PathwayBrowser/#/R-BTA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Bos taurus 67208 R-BTA-9023909 https://reactome.org/PathwayBrowser/#/R-BTA-9023909 C3PO hydrolyzes cleaved passenger strand IEA Bos taurus 67208 R-BTA-9023912 https://reactome.org/PathwayBrowser/#/R-BTA-9023912 AGO2 cleaves passenger strand of duplex siRNA IEA Bos taurus 67208 R-BTA-9833777 https://reactome.org/PathwayBrowser/#/R-BTA-9833777 PKR binds activating host RNA IEA Bos taurus 67208 R-CEL-2106615 https://reactome.org/PathwayBrowser/#/R-CEL-2106615 Removal of siRNA passenger strand IEA Caenorhabditis elegans 67208 R-CEL-2106625 https://reactome.org/PathwayBrowser/#/R-CEL-2106625 Duplex siRNA is loaded into Argonaute IEA Caenorhabditis elegans 67208 R-CEL-426464 https://reactome.org/PathwayBrowser/#/R-CEL-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Caenorhabditis elegans 67208 R-CEL-77613 https://reactome.org/PathwayBrowser/#/R-CEL-77613 Binding of ADAR2 homodimer to dsRNA duplex IEA Caenorhabditis elegans 67208 R-CEL-77615 https://reactome.org/PathwayBrowser/#/R-CEL-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Caenorhabditis elegans 67208 R-CEL-9023912 https://reactome.org/PathwayBrowser/#/R-CEL-9023912 AGO2 cleaves passenger strand of duplex siRNA IEA Caenorhabditis elegans 67208 R-CEL-9833777 https://reactome.org/PathwayBrowser/#/R-CEL-9833777 PKR binds activating host RNA IEA Caenorhabditis elegans 67208 R-CFA-2106615 https://reactome.org/PathwayBrowser/#/R-CFA-2106615 Removal of siRNA passenger strand IEA Canis familiaris 67208 R-CFA-2106625 https://reactome.org/PathwayBrowser/#/R-CFA-2106625 Duplex siRNA is loaded into Argonaute IEA Canis familiaris 67208 R-CFA-426464 https://reactome.org/PathwayBrowser/#/R-CFA-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Canis familiaris 67208 R-CFA-75090 https://reactome.org/PathwayBrowser/#/R-CFA-75090 Binding of ADAR1 homodimer to dsRNA duplex IEA Canis familiaris 67208 R-CFA-77613 https://reactome.org/PathwayBrowser/#/R-CFA-77613 Binding of ADAR2 homodimer to dsRNA duplex IEA Canis familiaris 67208 R-CFA-77614 https://reactome.org/PathwayBrowser/#/R-CFA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Canis familiaris 67208 R-CFA-77615 https://reactome.org/PathwayBrowser/#/R-CFA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Canis familiaris 67208 R-CFA-9023912 https://reactome.org/PathwayBrowser/#/R-CFA-9023912 AGO2 cleaves passenger strand of duplex siRNA IEA Canis familiaris 67208 R-CFA-9833777 https://reactome.org/PathwayBrowser/#/R-CFA-9833777 PKR binds activating host RNA IEA Canis familiaris 67208 R-DME-2106615 https://reactome.org/PathwayBrowser/#/R-DME-2106615 Removal of siRNA passenger strand IEA Drosophila melanogaster 67208 R-DME-2106625 https://reactome.org/PathwayBrowser/#/R-DME-2106625 Duplex siRNA is loaded into Argonaute IEA Drosophila melanogaster 67208 R-DME-426464 https://reactome.org/PathwayBrowser/#/R-DME-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Drosophila melanogaster 67208 R-DME-77613 https://reactome.org/PathwayBrowser/#/R-DME-77613 Binding of ADAR2 homodimer to dsRNA duplex IEA Drosophila melanogaster 67208 R-DME-77615 https://reactome.org/PathwayBrowser/#/R-DME-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Drosophila melanogaster 67208 R-DME-9023909 https://reactome.org/PathwayBrowser/#/R-DME-9023909 C3PO hydrolyzes cleaved passenger strand IEA Drosophila melanogaster 67208 R-DME-9023912 https://reactome.org/PathwayBrowser/#/R-DME-9023912 AGO2 cleaves passenger strand of duplex siRNA IEA Drosophila melanogaster 67208 R-DME-9833777 https://reactome.org/PathwayBrowser/#/R-DME-9833777 PKR binds activating host RNA IEA Drosophila melanogaster 67208 R-DRE-9833777 https://reactome.org/PathwayBrowser/#/R-DRE-9833777 PKR binds activating host RNA IEA Danio rerio 67208 R-GGA-2106615 https://reactome.org/PathwayBrowser/#/R-GGA-2106615 Removal of siRNA passenger strand IEA Gallus gallus 67208 R-GGA-2106625 https://reactome.org/PathwayBrowser/#/R-GGA-2106625 Duplex siRNA is loaded into Argonaute IEA Gallus gallus 67208 R-GGA-426464 https://reactome.org/PathwayBrowser/#/R-GGA-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Gallus gallus 67208 R-GGA-75090 https://reactome.org/PathwayBrowser/#/R-GGA-75090 Binding of ADAR1 homodimer to dsRNA duplex IEA Gallus gallus 67208 R-GGA-77614 https://reactome.org/PathwayBrowser/#/R-GGA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Gallus gallus 67208 R-GGA-9023909 https://reactome.org/PathwayBrowser/#/R-GGA-9023909 C3PO hydrolyzes cleaved passenger strand IEA Gallus gallus 67208 R-GGA-9023912 https://reactome.org/PathwayBrowser/#/R-GGA-9023912 AGO2 cleaves passenger strand of duplex siRNA IEA Gallus gallus 67208 R-GGA-9833777 https://reactome.org/PathwayBrowser/#/R-GGA-9833777 PKR binds activating host RNA IEA Gallus gallus 67208 R-HSA-168092 https://reactome.org/PathwayBrowser/#/R-HSA-168092 Viral dsRNA binds the Toll-Like Receptor 3 (TLR3) TAS Homo sapiens 67208 R-HSA-168891 https://reactome.org/PathwayBrowser/#/R-HSA-168891 Binding of NS1 to dsRNA TAS Homo sapiens 67208 R-HSA-168909 https://reactome.org/PathwayBrowser/#/R-HSA-168909 viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58 bind MAVS TAS Homo sapiens 67208 R-HSA-168910 https://reactome.org/PathwayBrowser/#/R-HSA-168910 RIP1 facilitates IKK complex phosphorylation TAS Homo sapiens 67208 R-HSA-168929 https://reactome.org/PathwayBrowser/#/R-HSA-168929 Viral dsRNA:TLR3 recruits TRIF (TICAM1) TAS Homo sapiens 67208 R-HSA-168930 https://reactome.org/PathwayBrowser/#/R-HSA-168930 Viral dsRNA:TLR3:TRIF complex recruits RIP1 TAS Homo sapiens 67208 R-HSA-168934 https://reactome.org/PathwayBrowser/#/R-HSA-168934 MAVS interacts with RIPK1 and FADD TAS Homo sapiens 67208 R-HSA-168935 https://reactome.org/PathwayBrowser/#/R-HSA-168935 viral dsRNA binds DDX58 TAS Homo sapiens 67208 R-HSA-177690 https://reactome.org/PathwayBrowser/#/R-HSA-177690 Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex TAS Homo sapiens 67208 R-HSA-177692 https://reactome.org/PathwayBrowser/#/R-HSA-177692 Activation of recruited TAK1 within the activated TLR3 complex TAS Homo sapiens 67208 R-HSA-177694 https://reactome.org/PathwayBrowser/#/R-HSA-177694 Viral dsRNA:TLR3:TICAM1 complex recruits TRAF6 TAS Homo sapiens 67208 R-HSA-1964482 https://reactome.org/PathwayBrowser/#/R-HSA-1964482 RNA polymerase III transcribes microbial dsDNA to dsRNA TAS Homo sapiens 67208 R-HSA-203862 https://reactome.org/PathwayBrowser/#/R-HSA-203862 Dicer cleaves pre-miRNA to yield duplex miRNA TAS Homo sapiens 67208 R-HSA-203893 https://reactome.org/PathwayBrowser/#/R-HSA-203893 Microprocessor complex cleaves pri-miRNA to pre-miRNA TAS Homo sapiens 67208 R-HSA-203901 https://reactome.org/PathwayBrowser/#/R-HSA-203901 Pol II mediated transcription of microRNA genes TAS Homo sapiens 67208 R-HSA-203906 https://reactome.org/PathwayBrowser/#/R-HSA-203906 Exportin complex translocates pre-miRNA to cytosol TAS Homo sapiens 67208 R-HSA-203922 https://reactome.org/PathwayBrowser/#/R-HSA-203922 Exportin-5 recognizes 3' overhang of pre-miRNA TAS Homo sapiens 67208 R-HSA-2106614 https://reactome.org/PathwayBrowser/#/R-HSA-2106614 Duplex miRNA is loaded into Argonaute TAS Homo sapiens 67208 R-HSA-2106615 https://reactome.org/PathwayBrowser/#/R-HSA-2106615 Removal of siRNA passenger strand TAS Homo sapiens 67208 R-HSA-2106625 https://reactome.org/PathwayBrowser/#/R-HSA-2106625 Duplex siRNA is loaded into Argonaute TAS Homo sapiens 67208 R-HSA-210805 https://reactome.org/PathwayBrowser/#/R-HSA-210805 Removal of miRNA passenger strand TAS Homo sapiens 67208 R-HSA-426464 https://reactome.org/PathwayBrowser/#/R-HSA-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA TAS Homo sapiens 67208 R-HSA-450259 https://reactome.org/PathwayBrowser/#/R-HSA-450259 Auto ubiqitination of TRAF6 bound to viral dsRNS:TLR3:TICAM1 complex TAS Homo sapiens 67208 R-HSA-5602549 https://reactome.org/PathwayBrowser/#/R-HSA-5602549 Defective TLR3 does not bind viral dsRNA TAS Homo sapiens 67208 R-HSA-5602624 https://reactome.org/PathwayBrowser/#/R-HSA-5602624 Defective TRAF3 does not transmit the signal TAS Homo sapiens 67208 R-HSA-5602712 https://reactome.org/PathwayBrowser/#/R-HSA-5602712 TICAM1 deficiency blocks TLR3 pathway TAS Homo sapiens 67208 R-HSA-75090 https://reactome.org/PathwayBrowser/#/R-HSA-75090 Binding of ADAR1 homodimer to dsRNA duplex TAS Homo sapiens 67208 R-HSA-77612 https://reactome.org/PathwayBrowser/#/R-HSA-77612 Formation of dsRNA structure by looping TAS Homo sapiens 67208 R-HSA-77613 https://reactome.org/PathwayBrowser/#/R-HSA-77613 Binding of ADAR2 homodimer to dsRNA duplex TAS Homo sapiens 67208 R-HSA-77614 https://reactome.org/PathwayBrowser/#/R-HSA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) TAS Homo sapiens 67208 R-HSA-77615 https://reactome.org/PathwayBrowser/#/R-HSA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) TAS Homo sapiens 67208 R-HSA-847070 https://reactome.org/PathwayBrowser/#/R-HSA-847070 Phosphorylated TAK1 dissociates from the TLR3 receptor complex TAS Homo sapiens 67208 R-HSA-8985091 https://reactome.org/PathwayBrowser/#/R-HSA-8985091 OAS3 produces oligoadenylates TAS Homo sapiens 67208 R-HSA-8985097 https://reactome.org/PathwayBrowser/#/R-HSA-8985097 OAS2 dimerizes TAS Homo sapiens 67208 R-HSA-8985104 https://reactome.org/PathwayBrowser/#/R-HSA-8985104 OAS2 produces oligoadenylates TAS Homo sapiens 67208 R-HSA-8985138 https://reactome.org/PathwayBrowser/#/R-HSA-8985138 OAS2 binds viral dsRNA TAS Homo sapiens 67208 R-HSA-8985157 https://reactome.org/PathwayBrowser/#/R-HSA-8985157 OAS3 binds viral dsRNA TAS Homo sapiens 67208 R-HSA-9013889 https://reactome.org/PathwayBrowser/#/R-HSA-9013889 TLR3-induced ripoptosome assembly TAS Homo sapiens 67208 R-HSA-9013895 https://reactome.org/PathwayBrowser/#/R-HSA-9013895 Caspase-8 processing within TLR3 complex TAS Homo sapiens 67208 R-HSA-9013963 https://reactome.org/PathwayBrowser/#/R-HSA-9013963 RIP3 binds TICAM1 within TLR3 complex to mediate necroptosis TAS Homo sapiens 67208 R-HSA-9013974 https://reactome.org/PathwayBrowser/#/R-HSA-9013974 Auto-ubiquitination of TRAF3 within activated TLR3 complex TAS Homo sapiens 67208 R-HSA-9013978 https://reactome.org/PathwayBrowser/#/R-HSA-9013978 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex TAS Homo sapiens 67208 R-HSA-9013979 https://reactome.org/PathwayBrowser/#/R-HSA-9013979 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR3 TAS Homo sapiens 67208 R-HSA-9013985 https://reactome.org/PathwayBrowser/#/R-HSA-9013985 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR3 TAS Homo sapiens 67208 R-HSA-9013990 https://reactome.org/PathwayBrowser/#/R-HSA-9013990 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TICAM1:TLR3:viral dsRNA TAS Homo sapiens 67208 R-HSA-9013992 https://reactome.org/PathwayBrowser/#/R-HSA-9013992 TRAF3 binds to TRIF:activated TLR3 complex TAS Homo sapiens 67208 R-HSA-9014320 https://reactome.org/PathwayBrowser/#/R-HSA-9014320 SARM binds viral dsRNA:TLR3:TICAM1 TAS Homo sapiens 67208 R-HSA-9014342 https://reactome.org/PathwayBrowser/#/R-HSA-9014342 K63-linked ubiquitination of RIP1 bound to the activated TLR complex TAS Homo sapiens 67208 R-HSA-9014343 https://reactome.org/PathwayBrowser/#/R-HSA-9014343 IKBKG subunit of IKK complex binds K63pUb- RIP1 within the TLR3 complex TAS Homo sapiens 67208 R-HSA-9023909 https://reactome.org/PathwayBrowser/#/R-HSA-9023909 C3PO hydrolyzes cleaved passenger strand TAS Homo sapiens 67208 R-HSA-9023912 https://reactome.org/PathwayBrowser/#/R-HSA-9023912 AGO2 cleaves passenger strand of duplex siRNA TAS Homo sapiens 67208 R-HSA-913725 https://reactome.org/PathwayBrowser/#/R-HSA-913725 viral dsRNA binds IFIH1:TKFC TAS Homo sapiens 67208 R-HSA-918224 https://reactome.org/PathwayBrowser/#/R-HSA-918224 DDX58 is K63 polyubiquitinated TAS Homo sapiens 67208 R-HSA-918225 https://reactome.org/PathwayBrowser/#/R-HSA-918225 TBK1/IKK epsilon complex interacts with MAVS bound TRAF3 TAS Homo sapiens 67208 R-HSA-918227 https://reactome.org/PathwayBrowser/#/R-HSA-918227 Recruitment of TRAF3 to MAVS TAS Homo sapiens 67208 R-HSA-918229 https://reactome.org/PathwayBrowser/#/R-HSA-918229 Phosphorylation and release of IRF3/IRF7 TAS Homo sapiens 67208 R-HSA-918230 https://reactome.org/PathwayBrowser/#/R-HSA-918230 Recruitment of TRAF6/TRAF2 to IPS-1 TAS Homo sapiens 67208 R-HSA-918232 https://reactome.org/PathwayBrowser/#/R-HSA-918232 Recruitment of IRF3,IRF7 TAS Homo sapiens 67208 R-HSA-933523 https://reactome.org/PathwayBrowser/#/R-HSA-933523 Dimerzation of procaspase-8, procaspase-10 TAS Homo sapiens 67208 R-HSA-933525 https://reactome.org/PathwayBrowser/#/R-HSA-933525 Phosphorylation and release of IRF7 TAS Homo sapiens 67208 R-HSA-933526 https://reactome.org/PathwayBrowser/#/R-HSA-933526 Recruitment of caspase-8 and -10 to FADD complex TAS Homo sapiens 67208 R-HSA-933527 https://reactome.org/PathwayBrowser/#/R-HSA-933527 Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6 TAS Homo sapiens 67208 R-HSA-933528 https://reactome.org/PathwayBrowser/#/R-HSA-933528 Interaction of MEKK1 with TRAF6 IEA Homo sapiens 67208 R-HSA-933530 https://reactome.org/PathwayBrowser/#/R-HSA-933530 Activation of IKK by MEKK1 TAS Homo sapiens 67208 R-HSA-933532 https://reactome.org/PathwayBrowser/#/R-HSA-933532 Processing of caspases TAS Homo sapiens 67208 R-HSA-933537 https://reactome.org/PathwayBrowser/#/R-HSA-933537 Recruitment of TANK to TRAF6 TAS Homo sapiens 67208 R-HSA-933538 https://reactome.org/PathwayBrowser/#/R-HSA-933538 Recruitment of IRF7 to TRAF6 TAS Homo sapiens 67208 R-HSA-933539 https://reactome.org/PathwayBrowser/#/R-HSA-933539 Recruitment of IKK complex TAS Homo sapiens 67208 R-HSA-936378 https://reactome.org/PathwayBrowser/#/R-HSA-936378 Inhibition of DDX58/IFIH1 signaling by ATG5:ATG12:MAVS IEA Homo sapiens 67208 R-HSA-936381 https://reactome.org/PathwayBrowser/#/R-HSA-936381 OTUD5 deubiquitinates TRAF3 TAS Homo sapiens 67208 R-HSA-936475 https://reactome.org/PathwayBrowser/#/R-HSA-936475 Negative regulation of DDX58/IFIH1 signaling by RNF216 TAS Homo sapiens 67208 R-HSA-937343 https://reactome.org/PathwayBrowser/#/R-HSA-937343 NLRC5 interacts with DDX58/IFIH1 TAS Homo sapiens 67208 R-HSA-9628444 https://reactome.org/PathwayBrowser/#/R-HSA-9628444 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation TAS Homo sapiens 67208 R-HSA-9705137 https://reactome.org/PathwayBrowser/#/R-HSA-9705137 TBK1 or IKBKE forms homodimers TAS Homo sapiens 67208 R-HSA-9705145 https://reactome.org/PathwayBrowser/#/R-HSA-9705145 TBK1, IKBKE form homodimers TAS Homo sapiens 67208 R-HSA-9705320 https://reactome.org/PathwayBrowser/#/R-HSA-9705320 TBK1, IKBKE are autophosphorylated at Ser172 TAS Homo sapiens 67208 R-HSA-9705323 https://reactome.org/PathwayBrowser/#/R-HSA-9705323 Phosphorylation of TBK1/IKBKE TAS Homo sapiens 67208 R-HSA-9828196 https://reactome.org/PathwayBrowser/#/R-HSA-9828196 TBK1 binds K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR3 TAS Homo sapiens 67208 R-HSA-9828200 https://reactome.org/PathwayBrowser/#/R-HSA-9828200 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 TAS Homo sapiens 67208 R-HSA-9828204 https://reactome.org/PathwayBrowser/#/R-HSA-9828204 IKKε (IKBKE) binds K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR3 TAS Homo sapiens 67208 R-HSA-9828205 https://reactome.org/PathwayBrowser/#/R-HSA-9828205 TBK1 is phosphorylated within the activated TLR3 complex TAS Homo sapiens 67208 R-HSA-9828209 https://reactome.org/PathwayBrowser/#/R-HSA-9828209 OPTN binds TBK1 within the activated TLR3 complex TAS Homo sapiens 67208 R-HSA-9830706 https://reactome.org/PathwayBrowser/#/R-HSA-9830706 IKKε (IKBKE) is phosphorylated within the activated TLR3 complex TAS Homo sapiens 67208 R-HSA-9830710 https://reactome.org/PathwayBrowser/#/R-HSA-9830710 IKKε (IKBKE) is ubiquitinated within the activated TLR3 complex TAS Homo sapiens 67208 R-HSA-9833393 https://reactome.org/PathwayBrowser/#/R-HSA-9833393 N interacts with IFIH1 TAS Homo sapiens 67208 R-HSA-9833723 https://reactome.org/PathwayBrowser/#/R-HSA-9833723 PKR forms a dimer TAS Homo sapiens 67208 R-HSA-9833777 https://reactome.org/PathwayBrowser/#/R-HSA-9833777 PKR binds activating host RNA TAS Homo sapiens 67208 R-HSA-9837448 https://reactome.org/PathwayBrowser/#/R-HSA-9837448 Formation of hRSV A dsRNA intermediate form TAS Homo sapiens 67208 R-HSA-9839016 https://reactome.org/PathwayBrowser/#/R-HSA-9839016 PKR binds viral dsRNA TAS Homo sapiens 67208 R-HSA-990526 https://reactome.org/PathwayBrowser/#/R-HSA-990526 Recruitment of ITCH and K48 ubiquitination of MAVS TAS Homo sapiens 67208 R-HSA-990528 https://reactome.org/PathwayBrowser/#/R-HSA-990528 Interaction of PCBP2 with MAVS TAS Homo sapiens 67208 R-MMU-2106615 https://reactome.org/PathwayBrowser/#/R-MMU-2106615 Removal of siRNA passenger strand IEA Mus musculus 67208 R-MMU-2106625 https://reactome.org/PathwayBrowser/#/R-MMU-2106625 Duplex siRNA is loaded into Argonaute IEA Mus musculus 67208 R-MMU-426464 https://reactome.org/PathwayBrowser/#/R-MMU-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Mus musculus 67208 R-MMU-75090 https://reactome.org/PathwayBrowser/#/R-MMU-75090 Binding of ADAR1 homodimer to dsRNA duplex IEA Mus musculus 67208 R-MMU-77613 https://reactome.org/PathwayBrowser/#/R-MMU-77613 Binding of ADAR2 homodimer to dsRNA duplex IEA Mus musculus 67208 R-MMU-77614 https://reactome.org/PathwayBrowser/#/R-MMU-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Mus musculus 67208 R-MMU-77615 https://reactome.org/PathwayBrowser/#/R-MMU-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Mus musculus 67208 R-MMU-9023909 https://reactome.org/PathwayBrowser/#/R-MMU-9023909 C3PO hydrolyzes cleaved passenger strand IEA Mus musculus 67208 R-MMU-9023912 https://reactome.org/PathwayBrowser/#/R-MMU-9023912 AGO2 cleaves passenger strand of duplex siRNA IEA Mus musculus 67208 R-MMU-9833777 https://reactome.org/PathwayBrowser/#/R-MMU-9833777 PKR binds activating host RNA IEA Mus musculus 67208 R-RNO-2106615 https://reactome.org/PathwayBrowser/#/R-RNO-2106615 Removal of siRNA passenger strand IEA Rattus norvegicus 67208 R-RNO-2106625 https://reactome.org/PathwayBrowser/#/R-RNO-2106625 Duplex siRNA is loaded into Argonaute IEA Rattus norvegicus 67208 R-RNO-426464 https://reactome.org/PathwayBrowser/#/R-RNO-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Rattus norvegicus 67208 R-RNO-75090 https://reactome.org/PathwayBrowser/#/R-RNO-75090 Binding of ADAR1 homodimer to dsRNA duplex IEA Rattus norvegicus 67208 R-RNO-77613 https://reactome.org/PathwayBrowser/#/R-RNO-77613 Binding of ADAR2 homodimer to dsRNA duplex IEA Rattus norvegicus 67208 R-RNO-77614 https://reactome.org/PathwayBrowser/#/R-RNO-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Rattus norvegicus 67208 R-RNO-77615 https://reactome.org/PathwayBrowser/#/R-RNO-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Rattus norvegicus 67208 R-RNO-9023909 https://reactome.org/PathwayBrowser/#/R-RNO-9023909 C3PO hydrolyzes cleaved passenger strand IEA Rattus norvegicus 67208 R-RNO-9023912 https://reactome.org/PathwayBrowser/#/R-RNO-9023912 AGO2 cleaves passenger strand of duplex siRNA IEA Rattus norvegicus 67208 R-RNO-9833777 https://reactome.org/PathwayBrowser/#/R-RNO-9833777 PKR binds activating host RNA IEA Rattus norvegicus 67208 R-SPO-9023909 https://reactome.org/PathwayBrowser/#/R-SPO-9023909 C3PO hydrolyzes cleaved passenger strand IEA Schizosaccharomyces pombe 67208 R-SPO-9023912 https://reactome.org/PathwayBrowser/#/R-SPO-9023912 AGO2 cleaves passenger strand of duplex siRNA IEA Schizosaccharomyces pombe 67208 R-SSC-2106615 https://reactome.org/PathwayBrowser/#/R-SSC-2106615 Removal of siRNA passenger strand IEA Sus scrofa 67208 R-SSC-2106625 https://reactome.org/PathwayBrowser/#/R-SSC-2106625 Duplex siRNA is loaded into Argonaute IEA Sus scrofa 67208 R-SSC-426464 https://reactome.org/PathwayBrowser/#/R-SSC-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Sus scrofa 67208 R-SSC-75090 https://reactome.org/PathwayBrowser/#/R-SSC-75090 Binding of ADAR1 homodimer to dsRNA duplex IEA Sus scrofa 67208 R-SSC-77613 https://reactome.org/PathwayBrowser/#/R-SSC-77613 Binding of ADAR2 homodimer to dsRNA duplex IEA Sus scrofa 67208 R-SSC-77614 https://reactome.org/PathwayBrowser/#/R-SSC-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Sus scrofa 67208 R-SSC-77615 https://reactome.org/PathwayBrowser/#/R-SSC-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Sus scrofa 67208 R-SSC-9023909 https://reactome.org/PathwayBrowser/#/R-SSC-9023909 C3PO hydrolyzes cleaved passenger strand IEA Sus scrofa 67208 R-SSC-9023912 https://reactome.org/PathwayBrowser/#/R-SSC-9023912 AGO2 cleaves passenger strand of duplex siRNA IEA Sus scrofa 67208 R-SSC-9833777 https://reactome.org/PathwayBrowser/#/R-SSC-9833777 PKR binds activating host RNA IEA Sus scrofa 67208 R-XTR-2106615 https://reactome.org/PathwayBrowser/#/R-XTR-2106615 Removal of siRNA passenger strand IEA Xenopus tropicalis 67208 R-XTR-2106625 https://reactome.org/PathwayBrowser/#/R-XTR-2106625 Duplex siRNA is loaded into Argonaute IEA Xenopus tropicalis 67208 R-XTR-426464 https://reactome.org/PathwayBrowser/#/R-XTR-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Xenopus tropicalis 67208 R-XTR-77613 https://reactome.org/PathwayBrowser/#/R-XTR-77613 Binding of ADAR2 homodimer to dsRNA duplex IEA Xenopus tropicalis 67208 R-XTR-77615 https://reactome.org/PathwayBrowser/#/R-XTR-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Xenopus tropicalis 67208 R-XTR-9023909 https://reactome.org/PathwayBrowser/#/R-XTR-9023909 C3PO hydrolyzes cleaved passenger strand IEA Xenopus tropicalis 67208 R-XTR-9023912 https://reactome.org/PathwayBrowser/#/R-XTR-9023912 AGO2 cleaves passenger strand of duplex siRNA IEA Xenopus tropicalis 67208 R-XTR-9833777 https://reactome.org/PathwayBrowser/#/R-XTR-9833777 PKR binds activating host RNA IEA Xenopus tropicalis 67237 R-BTA-9024326 https://reactome.org/PathwayBrowser/#/R-BTA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Bos taurus 67237 R-BTA-9024334 https://reactome.org/PathwayBrowser/#/R-BTA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Bos taurus 67237 R-BTA-9029517 https://reactome.org/PathwayBrowser/#/R-BTA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Bos taurus 67237 R-BTA-9029551 https://reactome.org/PathwayBrowser/#/R-BTA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Bos taurus 67237 R-BTA-9029561 https://reactome.org/PathwayBrowser/#/R-BTA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Bos taurus 67237 R-BTA-9029566 https://reactome.org/PathwayBrowser/#/R-BTA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Bos taurus 67237 R-BTA-9029580 https://reactome.org/PathwayBrowser/#/R-BTA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Bos taurus 67237 R-CFA-9024326 https://reactome.org/PathwayBrowser/#/R-CFA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Canis familiaris 67237 R-CFA-9024334 https://reactome.org/PathwayBrowser/#/R-CFA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Canis familiaris 67237 R-CFA-9029517 https://reactome.org/PathwayBrowser/#/R-CFA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Canis familiaris 67237 R-CFA-9029551 https://reactome.org/PathwayBrowser/#/R-CFA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Canis familiaris 67237 R-CFA-9029561 https://reactome.org/PathwayBrowser/#/R-CFA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Canis familiaris 67237 R-CFA-9029566 https://reactome.org/PathwayBrowser/#/R-CFA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Canis familiaris 67237 R-CFA-9029580 https://reactome.org/PathwayBrowser/#/R-CFA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Canis familiaris 67237 R-DME-9024326 https://reactome.org/PathwayBrowser/#/R-DME-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Drosophila melanogaster 67237 R-DME-9024334 https://reactome.org/PathwayBrowser/#/R-DME-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Drosophila melanogaster 67237 R-DME-9029517 https://reactome.org/PathwayBrowser/#/R-DME-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Drosophila melanogaster 67237 R-DME-9029551 https://reactome.org/PathwayBrowser/#/R-DME-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Drosophila melanogaster 67237 R-DME-9029561 https://reactome.org/PathwayBrowser/#/R-DME-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Drosophila melanogaster 67237 R-DME-9029566 https://reactome.org/PathwayBrowser/#/R-DME-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Drosophila melanogaster 67237 R-DME-9029580 https://reactome.org/PathwayBrowser/#/R-DME-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Drosophila melanogaster 67237 R-HSA-9024326 https://reactome.org/PathwayBrowser/#/R-HSA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex TAS Homo sapiens 67237 R-HSA-9024334 https://reactome.org/PathwayBrowser/#/R-HSA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene TAS Homo sapiens 67237 R-HSA-9024361 https://reactome.org/PathwayBrowser/#/R-HSA-9024361 Expression of ABCG1 regulated by NR1H2,3 TAS Homo sapiens 67237 R-HSA-9024386 https://reactome.org/PathwayBrowser/#/R-HSA-9024386 Oxysterol-induced binding of NR1H2,3:RXR to the ABCG1 gene TAS Homo sapiens 67237 R-HSA-9028524 https://reactome.org/PathwayBrowser/#/R-HSA-9028524 NR1H3, NRIP1 bind the PCK1 gene TAS Homo sapiens 67237 R-HSA-9028525 https://reactome.org/PathwayBrowser/#/R-HSA-9028525 NR1H2 or NR1H3, NRIP1 bind the SREBF1 gene TAS Homo sapiens 67237 R-HSA-9028526 https://reactome.org/PathwayBrowser/#/R-HSA-9028526 NR1H2 or NR1H3, NRIP1 bind the SCD gene TAS Homo sapiens 67237 R-HSA-9028533 https://reactome.org/PathwayBrowser/#/R-HSA-9028533 NR1H2,3, NRIP1 bind the FASN gene TAS Homo sapiens 67237 R-HSA-9029517 https://reactome.org/PathwayBrowser/#/R-HSA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex TAS Homo sapiens 67237 R-HSA-9029521 https://reactome.org/PathwayBrowser/#/R-HSA-9029521 NR1H2,3 binds the ABCG5 gene TAS Homo sapiens 67237 R-HSA-9029531 https://reactome.org/PathwayBrowser/#/R-HSA-9029531 Expression of ABCG5 regulated by NR1H2,3 TAS Homo sapiens 67237 R-HSA-9029536 https://reactome.org/PathwayBrowser/#/R-HSA-9029536 Expression of UGT1A3 TAS Homo sapiens 67237 R-HSA-9029551 https://reactome.org/PathwayBrowser/#/R-HSA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex TAS Homo sapiens 67237 R-HSA-9029555 https://reactome.org/PathwayBrowser/#/R-HSA-9029555 NR1H2,3 binds the ABCG8 gene TAS Homo sapiens 67237 R-HSA-9029561 https://reactome.org/PathwayBrowser/#/R-HSA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter TAS Homo sapiens 67237 R-HSA-9029566 https://reactome.org/PathwayBrowser/#/R-HSA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene TAS Homo sapiens 67237 R-HSA-9029580 https://reactome.org/PathwayBrowser/#/R-HSA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex TAS Homo sapiens 67237 R-HSA-9029591 https://reactome.org/PathwayBrowser/#/R-HSA-9029591 Expression of ABCG8 regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9031510 https://reactome.org/PathwayBrowser/#/R-HSA-9031510 Expression of APOC1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9031512 https://reactome.org/PathwayBrowser/#/R-HSA-9031512 Expression of APOE regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9031518 https://reactome.org/PathwayBrowser/#/R-HSA-9031518 NR1H2,3 binds the APOC1 gene TAS Homo sapiens 67237 R-HSA-9031521 https://reactome.org/PathwayBrowser/#/R-HSA-9031521 NR1H2,3 binds the APOC2 gene TAS Homo sapiens 67237 R-HSA-9031522 https://reactome.org/PathwayBrowser/#/R-HSA-9031522 NR1H2,3 binds the APOE gene TAS Homo sapiens 67237 R-HSA-9031527 https://reactome.org/PathwayBrowser/#/R-HSA-9031527 Expression of APOC2 regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9035133 https://reactome.org/PathwayBrowser/#/R-HSA-9035133 NR1H2,3 binds the CETP gene TAS Homo sapiens 67237 R-HSA-9035143 https://reactome.org/PathwayBrowser/#/R-HSA-9035143 NR1H2,3 binds the APOC4 gene TAS Homo sapiens 67237 R-HSA-9035167 https://reactome.org/PathwayBrowser/#/R-HSA-9035167 NR1H2,3 binds the EEPD1 gene TAS Homo sapiens 67237 R-HSA-9035169 https://reactome.org/PathwayBrowser/#/R-HSA-9035169 Expression of CETP regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9035180 https://reactome.org/PathwayBrowser/#/R-HSA-9035180 Expression of EEPD1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9035185 https://reactome.org/PathwayBrowser/#/R-HSA-9035185 NR1H2,3 binds the NR1H3 gene TAS Homo sapiens 67237 R-HSA-9035279 https://reactome.org/PathwayBrowser/#/R-HSA-9035279 Expression of APOC4 regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9035281 https://reactome.org/PathwayBrowser/#/R-HSA-9035281 NR1H3 gene transcription regulated by NR1H2,3 TAS Homo sapiens 67237 R-HSA-9605051 https://reactome.org/PathwayBrowser/#/R-HSA-9605051 Expression of PCK1 regulated by NR1H3 TAS Homo sapiens 67237 R-HSA-9605056 https://reactome.org/PathwayBrowser/#/R-HSA-9605056 Expression of SREBF1 (SREBP1) regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9605057 https://reactome.org/PathwayBrowser/#/R-HSA-9605057 ABCA1 gene transcription regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9605060 https://reactome.org/PathwayBrowser/#/R-HSA-9605060 Expression of SCD regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9605063 https://reactome.org/PathwayBrowser/#/R-HSA-9605063 Expression of FASN regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9607342 https://reactome.org/PathwayBrowser/#/R-HSA-9607342 Expression of FABP6 regulated by NR1H2,3 TAS Homo sapiens 67237 R-HSA-9608039 https://reactome.org/PathwayBrowser/#/R-HSA-9608039 NR1H2,3 binds the PLIN1 gene TAS Homo sapiens 67237 R-HSA-9608048 https://reactome.org/PathwayBrowser/#/R-HSA-9608048 Expression of PLIN1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9618394 https://reactome.org/PathwayBrowser/#/R-HSA-9618394 ARL4C gene transcription regulated by NR1H2,3 TAS Homo sapiens 67237 R-HSA-9618407 https://reactome.org/PathwayBrowser/#/R-HSA-9618407 NR1H2,3 binds the ARL4C gene TAS Homo sapiens 67237 R-HSA-9623365 https://reactome.org/PathwayBrowser/#/R-HSA-9623365 Expression of MYLIP regulated by NR1H2,3 TAS Homo sapiens 67237 R-HSA-9623366 https://reactome.org/PathwayBrowser/#/R-HSA-9623366 NR1H2,3 binds the MYLIP gene TAS Homo sapiens 67237 R-HSA-9624353 https://reactome.org/PathwayBrowser/#/R-HSA-9624353 NR1H2,3 binds the PLTP gene TAS Homo sapiens 67237 R-HSA-9624365 https://reactome.org/PathwayBrowser/#/R-HSA-9624365 Expression of PLTP regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9631296 https://reactome.org/PathwayBrowser/#/R-HSA-9631296 NR1H2,3 binds the FABP6 gene TAS Homo sapiens 67237 R-HSA-9657767 https://reactome.org/PathwayBrowser/#/R-HSA-9657767 Expression of APOD regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9657775 https://reactome.org/PathwayBrowser/#/R-HSA-9657775 Expression of ANGPTL3 regulated by NR1H2 or NR1H3 TAS Homo sapiens 67237 R-HSA-9657786 https://reactome.org/PathwayBrowser/#/R-HSA-9657786 NR1H2,3 binds the APOD gene TAS Homo sapiens 67237 R-HSA-9657836 https://reactome.org/PathwayBrowser/#/R-HSA-9657836 NR1H2,3 binds the ANGPTL3 gene TAS Homo sapiens 67237 R-MMU-9024326 https://reactome.org/PathwayBrowser/#/R-MMU-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Mus musculus 67237 R-MMU-9024334 https://reactome.org/PathwayBrowser/#/R-MMU-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Mus musculus 67237 R-MMU-9029517 https://reactome.org/PathwayBrowser/#/R-MMU-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Mus musculus 67237 R-MMU-9029551 https://reactome.org/PathwayBrowser/#/R-MMU-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Mus musculus 67237 R-MMU-9029561 https://reactome.org/PathwayBrowser/#/R-MMU-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Mus musculus 67237 R-MMU-9029566 https://reactome.org/PathwayBrowser/#/R-MMU-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Mus musculus 67237 R-MMU-9029580 https://reactome.org/PathwayBrowser/#/R-MMU-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Mus musculus 67237 R-RNO-9024326 https://reactome.org/PathwayBrowser/#/R-RNO-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Rattus norvegicus 67237 R-RNO-9024334 https://reactome.org/PathwayBrowser/#/R-RNO-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Rattus norvegicus 67237 R-RNO-9029517 https://reactome.org/PathwayBrowser/#/R-RNO-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Rattus norvegicus 67237 R-RNO-9029551 https://reactome.org/PathwayBrowser/#/R-RNO-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Rattus norvegicus 67237 R-RNO-9029561 https://reactome.org/PathwayBrowser/#/R-RNO-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Rattus norvegicus 67237 R-RNO-9029566 https://reactome.org/PathwayBrowser/#/R-RNO-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Rattus norvegicus 67237 R-RNO-9029580 https://reactome.org/PathwayBrowser/#/R-RNO-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Rattus norvegicus 67237 R-SSC-9024326 https://reactome.org/PathwayBrowser/#/R-SSC-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Sus scrofa 67237 R-SSC-9024334 https://reactome.org/PathwayBrowser/#/R-SSC-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Sus scrofa 67237 R-SSC-9029517 https://reactome.org/PathwayBrowser/#/R-SSC-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Sus scrofa 67237 R-SSC-9029551 https://reactome.org/PathwayBrowser/#/R-SSC-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Sus scrofa 67237 R-SSC-9029561 https://reactome.org/PathwayBrowser/#/R-SSC-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Sus scrofa 67237 R-SSC-9029566 https://reactome.org/PathwayBrowser/#/R-SSC-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Sus scrofa 67237 R-SSC-9029580 https://reactome.org/PathwayBrowser/#/R-SSC-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Sus scrofa 67237 R-XTR-9024326 https://reactome.org/PathwayBrowser/#/R-XTR-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Xenopus tropicalis 67237 R-XTR-9024334 https://reactome.org/PathwayBrowser/#/R-XTR-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Xenopus tropicalis 67237 R-XTR-9029517 https://reactome.org/PathwayBrowser/#/R-XTR-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Xenopus tropicalis 67237 R-XTR-9029566 https://reactome.org/PathwayBrowser/#/R-XTR-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Xenopus tropicalis 67271 R-HSA-2400010 https://reactome.org/PathwayBrowser/#/R-HSA-2400010 AKT inhibitors block AKT membrane recruitment TAS Homo sapiens 67272 R-HSA-2400010 https://reactome.org/PathwayBrowser/#/R-HSA-2400010 AKT inhibitors block AKT membrane recruitment TAS Homo sapiens 67890 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 67890 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 67890 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 67890 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 67890 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 67890 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 67890 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 67890 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 67890 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 6801 R-BTA-434650 https://reactome.org/PathwayBrowser/#/R-BTA-434650 MATEs mediate extrusion of xenobiotics IEA Bos taurus 6801 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 6801 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 6801 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 6801 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 6801 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 6801 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 6801 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 6801 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 6801 R-CFA-434650 https://reactome.org/PathwayBrowser/#/R-CFA-434650 MATEs mediate extrusion of xenobiotics IEA Canis familiaris 6801 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 6801 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 6801 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 6801 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 6801 R-DDI-434650 https://reactome.org/PathwayBrowser/#/R-DDI-434650 MATEs mediate extrusion of xenobiotics IEA Dictyostelium discoideum 6801 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 6801 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 6801 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 6801 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 6801 R-DRE-434650 https://reactome.org/PathwayBrowser/#/R-DRE-434650 MATEs mediate extrusion of xenobiotics IEA Danio rerio 6801 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 6801 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 6801 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 6801 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 6801 R-GGA-434650 https://reactome.org/PathwayBrowser/#/R-GGA-434650 MATEs mediate extrusion of xenobiotics IEA Gallus gallus 6801 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 6801 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 6801 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 6801 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 6801 R-HSA-434650 https://reactome.org/PathwayBrowser/#/R-HSA-434650 MATEs mediate extrusion of xenobiotics TAS Homo sapiens 6801 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 6801 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 6801 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 6801 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 6801 R-MMU-434650 https://reactome.org/PathwayBrowser/#/R-MMU-434650 MATEs mediate extrusion of xenobiotics IEA Mus musculus 6801 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 6801 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 6801 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 6801 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 6801 R-PFA-434650 https://reactome.org/PathwayBrowser/#/R-PFA-434650 MATEs mediate extrusion of xenobiotics IEA Plasmodium falciparum 6801 R-RNO-434650 https://reactome.org/PathwayBrowser/#/R-RNO-434650 MATEs mediate extrusion of xenobiotics IEA Rattus norvegicus 6801 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 6801 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 6801 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 6801 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 6801 R-SCE-434650 https://reactome.org/PathwayBrowser/#/R-SCE-434650 MATEs mediate extrusion of xenobiotics IEA Saccharomyces cerevisiae 6801 R-SPO-434650 https://reactome.org/PathwayBrowser/#/R-SPO-434650 MATEs mediate extrusion of xenobiotics IEA Schizosaccharomyces pombe 6801 R-SSC-434650 https://reactome.org/PathwayBrowser/#/R-SSC-434650 MATEs mediate extrusion of xenobiotics IEA Sus scrofa 6801 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 6801 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 6801 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 6801 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 6801 R-XTR-434650 https://reactome.org/PathwayBrowser/#/R-XTR-434650 MATEs mediate extrusion of xenobiotics IEA Xenopus tropicalis 6801 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 6801 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 6801 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 6801 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 6839 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 6839 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 6839 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 6839 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 6839 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 6839 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 6839 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 6839 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 6839 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 6839 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 6839 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 6839 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 6839 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 6839 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 6839 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 6839 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 6839 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 6839 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 6839 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 6839 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 6839 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 6839 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 68524 R-BTA-8850356 https://reactome.org/PathwayBrowser/#/R-BTA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Bos taurus 68524 R-CFA-8850356 https://reactome.org/PathwayBrowser/#/R-CFA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Canis familiaris 68524 R-GGA-8850356 https://reactome.org/PathwayBrowser/#/R-GGA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Gallus gallus 68524 R-HSA-8850356 https://reactome.org/PathwayBrowser/#/R-HSA-8850356 TCR binds microbial lipid-based antigen via CD1 TAS Homo sapiens 68524 R-MMU-8850356 https://reactome.org/PathwayBrowser/#/R-MMU-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Mus musculus 68524 R-RNO-8850356 https://reactome.org/PathwayBrowser/#/R-RNO-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Rattus norvegicus 68524 R-SSC-8850356 https://reactome.org/PathwayBrowser/#/R-SSC-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Sus scrofa 68558 R-BTA-417829 https://reactome.org/PathwayBrowser/#/R-BTA-417829 P2RY12 binds ADP IEA Bos taurus 68558 R-BTA-9611277 https://reactome.org/PathwayBrowser/#/R-BTA-9611277 P2RY12 binds P2RY12 antagonists IEA Bos taurus 68558 R-CFA-417829 https://reactome.org/PathwayBrowser/#/R-CFA-417829 P2RY12 binds ADP IEA Canis familiaris 68558 R-CFA-9611277 https://reactome.org/PathwayBrowser/#/R-CFA-9611277 P2RY12 binds P2RY12 antagonists IEA Canis familiaris 68558 R-DRE-417829 https://reactome.org/PathwayBrowser/#/R-DRE-417829 P2RY12 binds ADP IEA Danio rerio 68558 R-DRE-9611277 https://reactome.org/PathwayBrowser/#/R-DRE-9611277 P2RY12 binds P2RY12 antagonists IEA Danio rerio 68558 R-HSA-417829 https://reactome.org/PathwayBrowser/#/R-HSA-417829 P2RY12 binds ADP TAS Homo sapiens 68558 R-HSA-9611277 https://reactome.org/PathwayBrowser/#/R-HSA-9611277 P2RY12 binds P2RY12 antagonists TAS Homo sapiens 68558 R-MMU-417829 https://reactome.org/PathwayBrowser/#/R-MMU-417829 P2RY12 binds ADP IEA Mus musculus 68558 R-MMU-9611277 https://reactome.org/PathwayBrowser/#/R-MMU-9611277 P2RY12 binds P2RY12 antagonists IEA Mus musculus 68558 R-RNO-417829 https://reactome.org/PathwayBrowser/#/R-RNO-417829 P2RY12 binds ADP IEA Rattus norvegicus 68558 R-RNO-9611277 https://reactome.org/PathwayBrowser/#/R-RNO-9611277 P2RY12 binds P2RY12 antagonists IEA Rattus norvegicus 68558 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa 68558 R-SSC-9611277 https://reactome.org/PathwayBrowser/#/R-SSC-9611277 P2RY12 binds P2RY12 antagonists IEA Sus scrofa 68558 R-XTR-417829 https://reactome.org/PathwayBrowser/#/R-XTR-417829 P2RY12 binds ADP IEA Xenopus tropicalis 68558 R-XTR-9611277 https://reactome.org/PathwayBrowser/#/R-XTR-9611277 P2RY12 binds P2RY12 antagonists IEA Xenopus tropicalis 68575 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 68575 R-BTA-9611751 https://reactome.org/PathwayBrowser/#/R-BTA-9611751 β1,2-agonists bind ADRB1,2 IEA Bos taurus 68575 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 68575 R-CFA-9611751 https://reactome.org/PathwayBrowser/#/R-CFA-9611751 β1,2-agonists bind ADRB1,2 IEA Canis familiaris 68575 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 68575 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 68575 R-DME-9611751 https://reactome.org/PathwayBrowser/#/R-DME-9611751 β1,2-agonists bind ADRB1,2 IEA Drosophila melanogaster 68575 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 68575 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 68575 R-DRE-9611751 https://reactome.org/PathwayBrowser/#/R-DRE-9611751 β1,2-agonists bind ADRB1,2 IEA Danio rerio 68575 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 68575 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 68575 R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus 68575 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 68575 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 68575 R-HSA-9611751 https://reactome.org/PathwayBrowser/#/R-HSA-9611751 β1,2-agonists bind ADRB1,2 TAS Homo sapiens 68575 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 68575 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 68575 R-MMU-9611751 https://reactome.org/PathwayBrowser/#/R-MMU-9611751 β1,2-agonists bind ADRB1,2 IEA Mus musculus 68575 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 68575 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 68575 R-RNO-9611751 https://reactome.org/PathwayBrowser/#/R-RNO-9611751 β1,2-agonists bind ADRB1,2 IEA Rattus norvegicus 68575 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 68575 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 68575 R-SSC-9611751 https://reactome.org/PathwayBrowser/#/R-SSC-9611751 β1,2-agonists bind ADRB1,2 IEA Sus scrofa 68575 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 68575 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 68575 R-XTR-9611751 https://reactome.org/PathwayBrowser/#/R-XTR-9611751 β1,2-agonists bind ADRB1,2 IEA Xenopus tropicalis 68575 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 68579 R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 68579 R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 68579 R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 68579 R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 68579 R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 68579 R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 68579 R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 68579 R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 68579 R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 68579 R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 68579 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 68579 R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 68579 R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 68579 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 68579 R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 68579 R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 68579 R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 68579 R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 68579 R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 68579 R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 68579 R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 68579 R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 68579 R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 68579 R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 68579 R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 68579 R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 68579 R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 68579 R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 68579 R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 68579 R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 68595 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 68595 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 68595 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 68595 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 68595 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 68595 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 68595 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 68595 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 68647 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 68647 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 68647 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 68647 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 68647 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 68647 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 68647 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 68647 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 68647 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 68647 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 68647 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 68647 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 68647 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 68647 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 68647 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 68647 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 68647 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 68647 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 68647 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 68647 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 68647 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 68647 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 68647 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 68647 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 68647 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 68647 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 68647 R-HSA-9669870 https://reactome.org/PathwayBrowser/#/R-HSA-9669870 Regorafenib-resistant KIT mutants do not bind regorafenib TAS Homo sapiens 68647 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 68647 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 68647 R-HSA-9674408 https://reactome.org/PathwayBrowser/#/R-HSA-9674408 Regorafenib-resistant PDGFR mutants don't bind regorafenib TAS Homo sapiens 68647 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 68647 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 68647 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 68647 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 68647 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 68647 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 68647 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 68647 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 68647 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 68647 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 68647 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 68647 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 68647 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 68647 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 68647 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 68647 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 68647 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 6904 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 6904 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 6904 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 6904 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 6904 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 6904 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 6904 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 6904 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 6904 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 6904 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 6904 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 6904 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 6904 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 6904 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 6904 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 6904 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 6904 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 6904 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 6904 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 6904 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 6904 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 6904 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 6904 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 6904 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 6904 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 6904 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 6904 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 6904 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 6904 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 6904 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 6904 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 6904 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 6904 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 6904 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 6904 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 6904 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 6904 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 69236 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 69236 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 69236 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 69236 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 69236 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 69236 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 69236 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 69236 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 69236 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 69236 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 69236 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 69236 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 69236 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 69236 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 69236 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 69236 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 69236 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 69236 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 69236 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 69236 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 69236 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 69236 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 69236 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 69236 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 69236 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 69236 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 69236 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 69236 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 69236 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 69236 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 69236 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 69236 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 69236 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 69236 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 69236 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 69236 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 69236 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 69236 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 69236 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 69236 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 69236 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 69236 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 69441 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 69441 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 69441 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 69441 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 69441 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 69441 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 69441 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 69441 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 69441 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 69441 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 70712 R-BTA-2534076 https://reactome.org/PathwayBrowser/#/R-BTA-2534076 Unknown Nat N-acylates Gly in Gnat1 TAS Bos taurus 70712 R-HSA-2534040 https://reactome.org/PathwayBrowser/#/R-HSA-2534040 Unknown NAT N-acylates Gly in GNAT1 IEA Homo sapiens 70713 R-BTA-2534076 https://reactome.org/PathwayBrowser/#/R-BTA-2534076 Unknown Nat N-acylates Gly in Gnat1 TAS Bos taurus 70713 R-HSA-2534040 https://reactome.org/PathwayBrowser/#/R-HSA-2534040 Unknown NAT N-acylates Gly in GNAT1 IEA Homo sapiens 70752 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 70752 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 70752 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 70752 R-BTA-9015379 https://reactome.org/PathwayBrowser/#/R-BTA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Bos taurus 70752 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 70752 R-CFA-9015379 https://reactome.org/PathwayBrowser/#/R-CFA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Canis familiaris 70752 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 70752 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 70752 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 70752 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 70752 R-GGA-9015379 https://reactome.org/PathwayBrowser/#/R-GGA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Gallus gallus 70752 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 70752 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 70752 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 70752 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 70752 R-HSA-9015379 https://reactome.org/PathwayBrowser/#/R-HSA-9015379 Factor IIa inhibitors (compounds) binds IIa TAS Homo sapiens 70752 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 70752 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 70752 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 70752 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 70752 R-MMU-9015379 https://reactome.org/PathwayBrowser/#/R-MMU-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Mus musculus 70752 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 70752 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 70752 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 70752 R-RNO-9015379 https://reactome.org/PathwayBrowser/#/R-RNO-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Rattus norvegicus 70752 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 70752 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 70752 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 70752 R-SSC-9015379 https://reactome.org/PathwayBrowser/#/R-SSC-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Sus scrofa 70752 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 70752 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 70752 R-XTR-9015379 https://reactome.org/PathwayBrowser/#/R-XTR-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Xenopus tropicalis 70760 R-BTA-2187332 https://reactome.org/PathwayBrowser/#/R-BTA-2187332 Cytosolic CMs translocate to extracellular region IEA Bos taurus 70760 R-BTA-2395764 https://reactome.org/PathwayBrowser/#/R-BTA-2395764 atREs binds to nascent CM IEA Bos taurus 70760 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 70760 R-BTA-2395784 https://reactome.org/PathwayBrowser/#/R-BTA-2395784 Nascent CMs transform into mature CMs IEA Bos taurus 70760 R-BTA-2404131 https://reactome.org/PathwayBrowser/#/R-BTA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Bos taurus 70760 R-BTA-2404137 https://reactome.org/PathwayBrowser/#/R-BTA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 70760 R-BTA-2423785 https://reactome.org/PathwayBrowser/#/R-BTA-2423785 CR:atREs binds apoE and HSPG IEA Bos taurus 70760 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 70760 R-BTA-2453855 https://reactome.org/PathwayBrowser/#/R-BTA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 70760 R-BTA-975608 https://reactome.org/PathwayBrowser/#/R-BTA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Bos taurus 70760 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 70760 R-CFA-2187332 https://reactome.org/PathwayBrowser/#/R-CFA-2187332 Cytosolic CMs translocate to extracellular region IEA Canis familiaris 70760 R-CFA-2395764 https://reactome.org/PathwayBrowser/#/R-CFA-2395764 atREs binds to nascent CM IEA Canis familiaris 70760 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 70760 R-CFA-2395784 https://reactome.org/PathwayBrowser/#/R-CFA-2395784 Nascent CMs transform into mature CMs IEA Canis familiaris 70760 R-CFA-2404131 https://reactome.org/PathwayBrowser/#/R-CFA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Canis familiaris 70760 R-CFA-2404137 https://reactome.org/PathwayBrowser/#/R-CFA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 70760 R-CFA-2423785 https://reactome.org/PathwayBrowser/#/R-CFA-2423785 CR:atREs binds apoE and HSPG IEA Canis familiaris 70760 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 70760 R-CFA-2453855 https://reactome.org/PathwayBrowser/#/R-CFA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 70760 R-CFA-975608 https://reactome.org/PathwayBrowser/#/R-CFA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Canis familiaris 70760 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 70760 R-DRE-2404137 https://reactome.org/PathwayBrowser/#/R-DRE-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 70760 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 70760 R-DRE-2453855 https://reactome.org/PathwayBrowser/#/R-DRE-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 70760 R-DRE-975608 https://reactome.org/PathwayBrowser/#/R-DRE-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Danio rerio 70760 R-GGA-2187332 https://reactome.org/PathwayBrowser/#/R-GGA-2187332 Cytosolic CMs translocate to extracellular region IEA Gallus gallus 70760 R-GGA-2395764 https://reactome.org/PathwayBrowser/#/R-GGA-2395764 atREs binds to nascent CM IEA Gallus gallus 70760 R-GGA-2404137 https://reactome.org/PathwayBrowser/#/R-GGA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 70760 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 70760 R-GGA-2453855 https://reactome.org/PathwayBrowser/#/R-GGA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 70760 R-GGA-975608 https://reactome.org/PathwayBrowser/#/R-GGA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Gallus gallus 70760 R-HSA-2187332 https://reactome.org/PathwayBrowser/#/R-HSA-2187332 Cytosolic CMs translocate to extracellular region TAS Homo sapiens 70760 R-HSA-2395764 https://reactome.org/PathwayBrowser/#/R-HSA-2395764 atREs binds to nascent CM TAS Homo sapiens 70760 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 70760 R-HSA-2395784 https://reactome.org/PathwayBrowser/#/R-HSA-2395784 Nascent CMs transform into mature CMs TAS Homo sapiens 70760 R-HSA-2404131 https://reactome.org/PathwayBrowser/#/R-HSA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol TAS Homo sapiens 70760 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 70760 R-HSA-2404137 https://reactome.org/PathwayBrowser/#/R-HSA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 70760 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 70760 R-HSA-2423785 https://reactome.org/PathwayBrowser/#/R-HSA-2423785 CR:atREs binds apoE and HSPG TAS Homo sapiens 70760 R-HSA-2424254 https://reactome.org/PathwayBrowser/#/R-HSA-2424254 LDLR transports extracellular CR:atREs to cytosol IEA Homo sapiens 70760 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 70760 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 70760 R-HSA-2453855 https://reactome.org/PathwayBrowser/#/R-HSA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 70760 R-HSA-975608 https://reactome.org/PathwayBrowser/#/R-HSA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs TAS Homo sapiens 70760 R-MMU-2187332 https://reactome.org/PathwayBrowser/#/R-MMU-2187332 Cytosolic CMs translocate to extracellular region IEA Mus musculus 70760 R-MMU-2395764 https://reactome.org/PathwayBrowser/#/R-MMU-2395764 atREs binds to nascent CM IEA Mus musculus 70760 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 70760 R-MMU-2395784 https://reactome.org/PathwayBrowser/#/R-MMU-2395784 Nascent CMs transform into mature CMs IEA Mus musculus 70760 R-MMU-2404131 https://reactome.org/PathwayBrowser/#/R-MMU-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Mus musculus 70760 R-MMU-2404137 https://reactome.org/PathwayBrowser/#/R-MMU-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 70760 R-MMU-2423785 https://reactome.org/PathwayBrowser/#/R-MMU-2423785 CR:atREs binds apoE and HSPG IEA Mus musculus 70760 R-MMU-2425403 https://reactome.org/PathwayBrowser/#/R-MMU-2425403 Extracellular CR:atREs are transported to cytosol by Ldlr TAS Mus musculus 70760 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 70760 R-MMU-2453855 https://reactome.org/PathwayBrowser/#/R-MMU-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 70760 R-MMU-975608 https://reactome.org/PathwayBrowser/#/R-MMU-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Mus musculus 70760 R-RNO-2187332 https://reactome.org/PathwayBrowser/#/R-RNO-2187332 Cytosolic CMs translocate to extracellular region IEA Rattus norvegicus 70760 R-RNO-2395764 https://reactome.org/PathwayBrowser/#/R-RNO-2395764 atREs binds to nascent CM IEA Rattus norvegicus 70760 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 70760 R-RNO-2395784 https://reactome.org/PathwayBrowser/#/R-RNO-2395784 Nascent CMs transform into mature CMs IEA Rattus norvegicus 70760 R-RNO-2404131 https://reactome.org/PathwayBrowser/#/R-RNO-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Rattus norvegicus 70760 R-RNO-2404137 https://reactome.org/PathwayBrowser/#/R-RNO-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 70760 R-RNO-2423785 https://reactome.org/PathwayBrowser/#/R-RNO-2423785 CR:atREs binds apoE and HSPG IEA Rattus norvegicus 70760 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 70760 R-RNO-2453855 https://reactome.org/PathwayBrowser/#/R-RNO-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 70760 R-RNO-975608 https://reactome.org/PathwayBrowser/#/R-RNO-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Rattus norvegicus 70760 R-SSC-2187332 https://reactome.org/PathwayBrowser/#/R-SSC-2187332 Cytosolic CMs translocate to extracellular region IEA Sus scrofa 70760 R-SSC-2395764 https://reactome.org/PathwayBrowser/#/R-SSC-2395764 atREs binds to nascent CM IEA Sus scrofa 70760 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 70760 R-SSC-2395784 https://reactome.org/PathwayBrowser/#/R-SSC-2395784 Nascent CMs transform into mature CMs IEA Sus scrofa 70760 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa 70760 R-SSC-2404137 https://reactome.org/PathwayBrowser/#/R-SSC-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 70760 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa 70760 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 70760 R-SSC-2453855 https://reactome.org/PathwayBrowser/#/R-SSC-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 70760 R-SSC-975608 https://reactome.org/PathwayBrowser/#/R-SSC-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Sus scrofa 70760 R-XTR-2404137 https://reactome.org/PathwayBrowser/#/R-XTR-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 70760 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 70760 R-XTR-2453855 https://reactome.org/PathwayBrowser/#/R-XTR-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 70760 R-XTR-975608 https://reactome.org/PathwayBrowser/#/R-XTR-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Xenopus tropicalis 70761 R-BTA-2187332 https://reactome.org/PathwayBrowser/#/R-BTA-2187332 Cytosolic CMs translocate to extracellular region IEA Bos taurus 70761 R-BTA-2395764 https://reactome.org/PathwayBrowser/#/R-BTA-2395764 atREs binds to nascent CM IEA Bos taurus 70761 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 70761 R-BTA-2395784 https://reactome.org/PathwayBrowser/#/R-BTA-2395784 Nascent CMs transform into mature CMs IEA Bos taurus 70761 R-BTA-2404131 https://reactome.org/PathwayBrowser/#/R-BTA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Bos taurus 70761 R-BTA-2404137 https://reactome.org/PathwayBrowser/#/R-BTA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 70761 R-BTA-2423785 https://reactome.org/PathwayBrowser/#/R-BTA-2423785 CR:atREs binds apoE and HSPG IEA Bos taurus 70761 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 70761 R-BTA-2453855 https://reactome.org/PathwayBrowser/#/R-BTA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 70761 R-BTA-975608 https://reactome.org/PathwayBrowser/#/R-BTA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Bos taurus 70761 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 70761 R-CFA-2187332 https://reactome.org/PathwayBrowser/#/R-CFA-2187332 Cytosolic CMs translocate to extracellular region IEA Canis familiaris 70761 R-CFA-2395764 https://reactome.org/PathwayBrowser/#/R-CFA-2395764 atREs binds to nascent CM IEA Canis familiaris 70761 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 70761 R-CFA-2395784 https://reactome.org/PathwayBrowser/#/R-CFA-2395784 Nascent CMs transform into mature CMs IEA Canis familiaris 70761 R-CFA-2404131 https://reactome.org/PathwayBrowser/#/R-CFA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Canis familiaris 70761 R-CFA-2404137 https://reactome.org/PathwayBrowser/#/R-CFA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 70761 R-CFA-2423785 https://reactome.org/PathwayBrowser/#/R-CFA-2423785 CR:atREs binds apoE and HSPG IEA Canis familiaris 70761 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 70761 R-CFA-2453855 https://reactome.org/PathwayBrowser/#/R-CFA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 70761 R-CFA-975608 https://reactome.org/PathwayBrowser/#/R-CFA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Canis familiaris 70761 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 70761 R-DRE-2404137 https://reactome.org/PathwayBrowser/#/R-DRE-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 70761 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 70761 R-DRE-2453855 https://reactome.org/PathwayBrowser/#/R-DRE-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 70761 R-DRE-975608 https://reactome.org/PathwayBrowser/#/R-DRE-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Danio rerio 70761 R-GGA-2187332 https://reactome.org/PathwayBrowser/#/R-GGA-2187332 Cytosolic CMs translocate to extracellular region IEA Gallus gallus 70761 R-GGA-2395764 https://reactome.org/PathwayBrowser/#/R-GGA-2395764 atREs binds to nascent CM IEA Gallus gallus 70761 R-GGA-2404137 https://reactome.org/PathwayBrowser/#/R-GGA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 70761 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 70761 R-GGA-2453855 https://reactome.org/PathwayBrowser/#/R-GGA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 70761 R-GGA-975608 https://reactome.org/PathwayBrowser/#/R-GGA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Gallus gallus 70761 R-HSA-2187332 https://reactome.org/PathwayBrowser/#/R-HSA-2187332 Cytosolic CMs translocate to extracellular region TAS Homo sapiens 70761 R-HSA-2395764 https://reactome.org/PathwayBrowser/#/R-HSA-2395764 atREs binds to nascent CM TAS Homo sapiens 70761 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 70761 R-HSA-2395784 https://reactome.org/PathwayBrowser/#/R-HSA-2395784 Nascent CMs transform into mature CMs TAS Homo sapiens 70761 R-HSA-2404131 https://reactome.org/PathwayBrowser/#/R-HSA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol TAS Homo sapiens 70761 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 70761 R-HSA-2404137 https://reactome.org/PathwayBrowser/#/R-HSA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 70761 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 70761 R-HSA-2423785 https://reactome.org/PathwayBrowser/#/R-HSA-2423785 CR:atREs binds apoE and HSPG TAS Homo sapiens 70761 R-HSA-2424254 https://reactome.org/PathwayBrowser/#/R-HSA-2424254 LDLR transports extracellular CR:atREs to cytosol IEA Homo sapiens 70761 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 70761 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 70761 R-HSA-2453855 https://reactome.org/PathwayBrowser/#/R-HSA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 70761 R-HSA-975608 https://reactome.org/PathwayBrowser/#/R-HSA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs TAS Homo sapiens 70761 R-MMU-2187332 https://reactome.org/PathwayBrowser/#/R-MMU-2187332 Cytosolic CMs translocate to extracellular region IEA Mus musculus 70761 R-MMU-2395764 https://reactome.org/PathwayBrowser/#/R-MMU-2395764 atREs binds to nascent CM IEA Mus musculus 70761 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 70761 R-MMU-2395784 https://reactome.org/PathwayBrowser/#/R-MMU-2395784 Nascent CMs transform into mature CMs IEA Mus musculus 70761 R-MMU-2404131 https://reactome.org/PathwayBrowser/#/R-MMU-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Mus musculus 70761 R-MMU-2404137 https://reactome.org/PathwayBrowser/#/R-MMU-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 70761 R-MMU-2423785 https://reactome.org/PathwayBrowser/#/R-MMU-2423785 CR:atREs binds apoE and HSPG IEA Mus musculus 70761 R-MMU-2425403 https://reactome.org/PathwayBrowser/#/R-MMU-2425403 Extracellular CR:atREs are transported to cytosol by Ldlr TAS Mus musculus 70761 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 70761 R-MMU-2453855 https://reactome.org/PathwayBrowser/#/R-MMU-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 70761 R-MMU-975608 https://reactome.org/PathwayBrowser/#/R-MMU-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Mus musculus 70761 R-RNO-2187332 https://reactome.org/PathwayBrowser/#/R-RNO-2187332 Cytosolic CMs translocate to extracellular region IEA Rattus norvegicus 70761 R-RNO-2395764 https://reactome.org/PathwayBrowser/#/R-RNO-2395764 atREs binds to nascent CM IEA Rattus norvegicus 70761 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 70761 R-RNO-2395784 https://reactome.org/PathwayBrowser/#/R-RNO-2395784 Nascent CMs transform into mature CMs IEA Rattus norvegicus 70761 R-RNO-2404131 https://reactome.org/PathwayBrowser/#/R-RNO-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Rattus norvegicus 70761 R-RNO-2404137 https://reactome.org/PathwayBrowser/#/R-RNO-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 70761 R-RNO-2423785 https://reactome.org/PathwayBrowser/#/R-RNO-2423785 CR:atREs binds apoE and HSPG IEA Rattus norvegicus 70761 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 70761 R-RNO-2453855 https://reactome.org/PathwayBrowser/#/R-RNO-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 70761 R-RNO-975608 https://reactome.org/PathwayBrowser/#/R-RNO-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Rattus norvegicus 70761 R-SSC-2187332 https://reactome.org/PathwayBrowser/#/R-SSC-2187332 Cytosolic CMs translocate to extracellular region IEA Sus scrofa 70761 R-SSC-2395764 https://reactome.org/PathwayBrowser/#/R-SSC-2395764 atREs binds to nascent CM IEA Sus scrofa 70761 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 70761 R-SSC-2395784 https://reactome.org/PathwayBrowser/#/R-SSC-2395784 Nascent CMs transform into mature CMs IEA Sus scrofa 70761 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa 70761 R-SSC-2404137 https://reactome.org/PathwayBrowser/#/R-SSC-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 70761 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa 70761 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 70761 R-SSC-2453855 https://reactome.org/PathwayBrowser/#/R-SSC-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 70761 R-SSC-975608 https://reactome.org/PathwayBrowser/#/R-SSC-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Sus scrofa 70761 R-XTR-2404137 https://reactome.org/PathwayBrowser/#/R-XTR-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 70761 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 70761 R-XTR-2453855 https://reactome.org/PathwayBrowser/#/R-XTR-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 70761 R-XTR-975608 https://reactome.org/PathwayBrowser/#/R-XTR-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Xenopus tropicalis 70762 R-BTA-2187332 https://reactome.org/PathwayBrowser/#/R-BTA-2187332 Cytosolic CMs translocate to extracellular region IEA Bos taurus 70762 R-BTA-2395764 https://reactome.org/PathwayBrowser/#/R-BTA-2395764 atREs binds to nascent CM IEA Bos taurus 70762 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 70762 R-BTA-2395784 https://reactome.org/PathwayBrowser/#/R-BTA-2395784 Nascent CMs transform into mature CMs IEA Bos taurus 70762 R-BTA-2404131 https://reactome.org/PathwayBrowser/#/R-BTA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Bos taurus 70762 R-BTA-2404137 https://reactome.org/PathwayBrowser/#/R-BTA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 70762 R-BTA-2423785 https://reactome.org/PathwayBrowser/#/R-BTA-2423785 CR:atREs binds apoE and HSPG IEA Bos taurus 70762 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 70762 R-BTA-2453855 https://reactome.org/PathwayBrowser/#/R-BTA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 70762 R-BTA-975608 https://reactome.org/PathwayBrowser/#/R-BTA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Bos taurus 70762 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 70762 R-CFA-2187332 https://reactome.org/PathwayBrowser/#/R-CFA-2187332 Cytosolic CMs translocate to extracellular region IEA Canis familiaris 70762 R-CFA-2395764 https://reactome.org/PathwayBrowser/#/R-CFA-2395764 atREs binds to nascent CM IEA Canis familiaris 70762 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 70762 R-CFA-2395784 https://reactome.org/PathwayBrowser/#/R-CFA-2395784 Nascent CMs transform into mature CMs IEA Canis familiaris 70762 R-CFA-2404131 https://reactome.org/PathwayBrowser/#/R-CFA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Canis familiaris 70762 R-CFA-2404137 https://reactome.org/PathwayBrowser/#/R-CFA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 70762 R-CFA-2423785 https://reactome.org/PathwayBrowser/#/R-CFA-2423785 CR:atREs binds apoE and HSPG IEA Canis familiaris 70762 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 70762 R-CFA-2453855 https://reactome.org/PathwayBrowser/#/R-CFA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 70762 R-CFA-975608 https://reactome.org/PathwayBrowser/#/R-CFA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Canis familiaris 70762 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 70762 R-DRE-2404137 https://reactome.org/PathwayBrowser/#/R-DRE-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 70762 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 70762 R-DRE-2453855 https://reactome.org/PathwayBrowser/#/R-DRE-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 70762 R-DRE-975608 https://reactome.org/PathwayBrowser/#/R-DRE-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Danio rerio 70762 R-GGA-2187332 https://reactome.org/PathwayBrowser/#/R-GGA-2187332 Cytosolic CMs translocate to extracellular region IEA Gallus gallus 70762 R-GGA-2395764 https://reactome.org/PathwayBrowser/#/R-GGA-2395764 atREs binds to nascent CM IEA Gallus gallus 70762 R-GGA-2404137 https://reactome.org/PathwayBrowser/#/R-GGA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 70762 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 70762 R-GGA-2453855 https://reactome.org/PathwayBrowser/#/R-GGA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 70762 R-GGA-975608 https://reactome.org/PathwayBrowser/#/R-GGA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Gallus gallus 70762 R-HSA-2187332 https://reactome.org/PathwayBrowser/#/R-HSA-2187332 Cytosolic CMs translocate to extracellular region TAS Homo sapiens 70762 R-HSA-2395764 https://reactome.org/PathwayBrowser/#/R-HSA-2395764 atREs binds to nascent CM TAS Homo sapiens 70762 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 70762 R-HSA-2395784 https://reactome.org/PathwayBrowser/#/R-HSA-2395784 Nascent CMs transform into mature CMs TAS Homo sapiens 70762 R-HSA-2404131 https://reactome.org/PathwayBrowser/#/R-HSA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol TAS Homo sapiens 70762 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 70762 R-HSA-2404137 https://reactome.org/PathwayBrowser/#/R-HSA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 70762 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 70762 R-HSA-2423785 https://reactome.org/PathwayBrowser/#/R-HSA-2423785 CR:atREs binds apoE and HSPG TAS Homo sapiens 70762 R-HSA-2424254 https://reactome.org/PathwayBrowser/#/R-HSA-2424254 LDLR transports extracellular CR:atREs to cytosol IEA Homo sapiens 70762 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 70762 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 70762 R-HSA-2453855 https://reactome.org/PathwayBrowser/#/R-HSA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 70762 R-HSA-975608 https://reactome.org/PathwayBrowser/#/R-HSA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs TAS Homo sapiens 70762 R-MMU-2187332 https://reactome.org/PathwayBrowser/#/R-MMU-2187332 Cytosolic CMs translocate to extracellular region IEA Mus musculus 70762 R-MMU-2395764 https://reactome.org/PathwayBrowser/#/R-MMU-2395764 atREs binds to nascent CM IEA Mus musculus 70762 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 70762 R-MMU-2395784 https://reactome.org/PathwayBrowser/#/R-MMU-2395784 Nascent CMs transform into mature CMs IEA Mus musculus 70762 R-MMU-2404131 https://reactome.org/PathwayBrowser/#/R-MMU-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Mus musculus 70762 R-MMU-2404137 https://reactome.org/PathwayBrowser/#/R-MMU-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 70762 R-MMU-2423785 https://reactome.org/PathwayBrowser/#/R-MMU-2423785 CR:atREs binds apoE and HSPG IEA Mus musculus 70762 R-MMU-2425403 https://reactome.org/PathwayBrowser/#/R-MMU-2425403 Extracellular CR:atREs are transported to cytosol by Ldlr TAS Mus musculus 70762 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 70762 R-MMU-2453855 https://reactome.org/PathwayBrowser/#/R-MMU-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 70762 R-MMU-975608 https://reactome.org/PathwayBrowser/#/R-MMU-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Mus musculus 70762 R-RNO-2187332 https://reactome.org/PathwayBrowser/#/R-RNO-2187332 Cytosolic CMs translocate to extracellular region IEA Rattus norvegicus 70762 R-RNO-2395764 https://reactome.org/PathwayBrowser/#/R-RNO-2395764 atREs binds to nascent CM IEA Rattus norvegicus 70762 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 70762 R-RNO-2395784 https://reactome.org/PathwayBrowser/#/R-RNO-2395784 Nascent CMs transform into mature CMs IEA Rattus norvegicus 70762 R-RNO-2404131 https://reactome.org/PathwayBrowser/#/R-RNO-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Rattus norvegicus 70762 R-RNO-2404137 https://reactome.org/PathwayBrowser/#/R-RNO-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 70762 R-RNO-2423785 https://reactome.org/PathwayBrowser/#/R-RNO-2423785 CR:atREs binds apoE and HSPG IEA Rattus norvegicus 70762 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 70762 R-RNO-2453855 https://reactome.org/PathwayBrowser/#/R-RNO-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 70762 R-RNO-975608 https://reactome.org/PathwayBrowser/#/R-RNO-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Rattus norvegicus 70762 R-SSC-2187332 https://reactome.org/PathwayBrowser/#/R-SSC-2187332 Cytosolic CMs translocate to extracellular region IEA Sus scrofa 70762 R-SSC-2395764 https://reactome.org/PathwayBrowser/#/R-SSC-2395764 atREs binds to nascent CM IEA Sus scrofa 70762 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 70762 R-SSC-2395784 https://reactome.org/PathwayBrowser/#/R-SSC-2395784 Nascent CMs transform into mature CMs IEA Sus scrofa 70762 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa 70762 R-SSC-2404137 https://reactome.org/PathwayBrowser/#/R-SSC-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 70762 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa 70762 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 70762 R-SSC-2453855 https://reactome.org/PathwayBrowser/#/R-SSC-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 70762 R-SSC-975608 https://reactome.org/PathwayBrowser/#/R-SSC-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Sus scrofa 70762 R-XTR-2404137 https://reactome.org/PathwayBrowser/#/R-XTR-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 70762 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 70762 R-XTR-2453855 https://reactome.org/PathwayBrowser/#/R-XTR-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 70762 R-XTR-975608 https://reactome.org/PathwayBrowser/#/R-XTR-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Xenopus tropicalis 70974 R-BTA-382054 https://reactome.org/PathwayBrowser/#/R-BTA-382054 PDGF binds to extracellular matrix proteins IEA Bos taurus 70974 R-BTA-428518 https://reactome.org/PathwayBrowser/#/R-BTA-428518 Glypican-1 (GPC1) binds SLIT2 IEA Bos taurus 70974 R-CEL-382054 https://reactome.org/PathwayBrowser/#/R-CEL-382054 PDGF binds to extracellular matrix proteins IEA Caenorhabditis elegans 70974 R-CEL-428518 https://reactome.org/PathwayBrowser/#/R-CEL-428518 Glypican-1 (GPC1) binds SLIT2 IEA Caenorhabditis elegans 70974 R-CFA-382054 https://reactome.org/PathwayBrowser/#/R-CFA-382054 PDGF binds to extracellular matrix proteins IEA Canis familiaris 70974 R-CFA-428518 https://reactome.org/PathwayBrowser/#/R-CFA-428518 Glypican-1 (GPC1) binds SLIT2 IEA Canis familiaris 70974 R-DME-428518 https://reactome.org/PathwayBrowser/#/R-DME-428518 Glypican-1 (GPC1) binds SLIT2 IEA Drosophila melanogaster 70974 R-GGA-382054 https://reactome.org/PathwayBrowser/#/R-GGA-382054 PDGF binds to extracellular matrix proteins IEA Gallus gallus 70974 R-GGA-428518 https://reactome.org/PathwayBrowser/#/R-GGA-428518 Glypican-1 (GPC1) binds SLIT2 IEA Gallus gallus 70974 R-HSA-382054 https://reactome.org/PathwayBrowser/#/R-HSA-382054 PDGF binds to extracellular matrix proteins TAS Homo sapiens 70974 R-HSA-428518 https://reactome.org/PathwayBrowser/#/R-HSA-428518 Glypican-1 (GPC1) binds SLIT2 TAS Homo sapiens 70974 R-MMU-382054 https://reactome.org/PathwayBrowser/#/R-MMU-382054 PDGF binds to extracellular matrix proteins IEA Mus musculus 70974 R-MMU-428518 https://reactome.org/PathwayBrowser/#/R-MMU-428518 Glypican-1 (GPC1) binds SLIT2 IEA Mus musculus 70974 R-NUL-9010914 https://reactome.org/PathwayBrowser/#/R-NUL-9010914 Robo2 binds SLIT2 TAS Homo sapiens 70974 R-RNO-382054 https://reactome.org/PathwayBrowser/#/R-RNO-382054 PDGF binds to extracellular matrix proteins IEA Rattus norvegicus 70974 R-SSC-382054 https://reactome.org/PathwayBrowser/#/R-SSC-382054 PDGF binds to extracellular matrix proteins IEA Sus scrofa 70974 R-SSC-428518 https://reactome.org/PathwayBrowser/#/R-SSC-428518 Glypican-1 (GPC1) binds SLIT2 IEA Sus scrofa 70974 R-XTR-382054 https://reactome.org/PathwayBrowser/#/R-XTR-382054 PDGF binds to extracellular matrix proteins IEA Xenopus tropicalis 71063 R-BTA-2466767 https://reactome.org/PathwayBrowser/#/R-BTA-2466767 NRPE is a substrate for Abca4 TAS Bos taurus 71063 R-HSA-2466718 https://reactome.org/PathwayBrowser/#/R-HSA-2466718 NRPE dissociates to atRAL and PE TAS Homo sapiens 71063 R-HSA-2466749 https://reactome.org/PathwayBrowser/#/R-HSA-2466749 ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol IEA Homo sapiens 71063 R-HSA-2466764 https://reactome.org/PathwayBrowser/#/R-HSA-2466764 NRPE condenses with atRAL to form A2PE TAS Homo sapiens 71063 R-HSA-2466802 https://reactome.org/PathwayBrowser/#/R-HSA-2466802 Defective ABCA4 does not transport NRPE from disc membranes TAS Homo sapiens 71063 R-HSA-2466846 https://reactome.org/PathwayBrowser/#/R-HSA-2466846 atRAL can spontaneously react with PE to form NRPE TAS Homo sapiens 71219 R-BTA-389083 https://reactome.org/PathwayBrowser/#/R-BTA-389083 Autophosphorylation of PDGF alpha receptors IEA Bos taurus 71219 R-BTA-5213464 https://reactome.org/PathwayBrowser/#/R-BTA-5213464 RIPK1 is phosphorylated IEA Bos taurus 71219 R-BTA-5213466 https://reactome.org/PathwayBrowser/#/R-BTA-5213466 RIPK3 is phosphorylated IEA Bos taurus 71219 R-BTA-9674093 https://reactome.org/PathwayBrowser/#/R-BTA-9674093 PDGFRs bind type I TKI IEA Bos taurus 71219 R-BTA-9693978 https://reactome.org/PathwayBrowser/#/R-BTA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Bos taurus 71219 R-CEL-389083 https://reactome.org/PathwayBrowser/#/R-CEL-389083 Autophosphorylation of PDGF alpha receptors IEA Caenorhabditis elegans 71219 R-CEL-9674093 https://reactome.org/PathwayBrowser/#/R-CEL-9674093 PDGFRs bind type I TKI IEA Caenorhabditis elegans 71219 R-CFA-389083 https://reactome.org/PathwayBrowser/#/R-CFA-389083 Autophosphorylation of PDGF alpha receptors IEA Canis familiaris 71219 R-CFA-5213464 https://reactome.org/PathwayBrowser/#/R-CFA-5213464 RIPK1 is phosphorylated IEA Canis familiaris 71219 R-CFA-5213466 https://reactome.org/PathwayBrowser/#/R-CFA-5213466 RIPK3 is phosphorylated IEA Canis familiaris 71219 R-CFA-9674093 https://reactome.org/PathwayBrowser/#/R-CFA-9674093 PDGFRs bind type I TKI IEA Canis familiaris 71219 R-CFA-9693978 https://reactome.org/PathwayBrowser/#/R-CFA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Canis familiaris 71219 R-DME-389083 https://reactome.org/PathwayBrowser/#/R-DME-389083 Autophosphorylation of PDGF alpha receptors IEA Drosophila melanogaster 71219 R-DME-9674093 https://reactome.org/PathwayBrowser/#/R-DME-9674093 PDGFRs bind type I TKI IEA Drosophila melanogaster 71219 R-DRE-389083 https://reactome.org/PathwayBrowser/#/R-DRE-389083 Autophosphorylation of PDGF alpha receptors IEA Danio rerio 71219 R-DRE-9674093 https://reactome.org/PathwayBrowser/#/R-DRE-9674093 PDGFRs bind type I TKI IEA Danio rerio 71219 R-GGA-389083 https://reactome.org/PathwayBrowser/#/R-GGA-389083 Autophosphorylation of PDGF alpha receptors IEA Gallus gallus 71219 R-GGA-9674093 https://reactome.org/PathwayBrowser/#/R-GGA-9674093 PDGFRs bind type I TKI IEA Gallus gallus 71219 R-HSA-2029992 https://reactome.org/PathwayBrowser/#/R-HSA-2029992 Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants TAS Homo sapiens 71219 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 71219 R-HSA-389083 https://reactome.org/PathwayBrowser/#/R-HSA-389083 Autophosphorylation of PDGF alpha receptors TAS Homo sapiens 71219 R-HSA-5213464 https://reactome.org/PathwayBrowser/#/R-HSA-5213464 RIPK1 is phosphorylated TAS Homo sapiens 71219 R-HSA-5213466 https://reactome.org/PathwayBrowser/#/R-HSA-5213466 RIPK3 is phosphorylated TAS Homo sapiens 71219 R-HSA-9674093 https://reactome.org/PathwayBrowser/#/R-HSA-9674093 PDGFRs bind type I TKI TAS Homo sapiens 71219 R-HSA-9674427 https://reactome.org/PathwayBrowser/#/R-HSA-9674427 PDGFR mutants bind type I TKIs TAS Homo sapiens 71219 R-HSA-9693978 https://reactome.org/PathwayBrowser/#/R-HSA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 TAS Homo sapiens 71219 R-MMU-389083 https://reactome.org/PathwayBrowser/#/R-MMU-389083 Autophosphorylation of PDGF alpha receptors IEA Mus musculus 71219 R-MMU-5213464 https://reactome.org/PathwayBrowser/#/R-MMU-5213464 RIPK1 is phosphorylated IEA Mus musculus 71219 R-MMU-5213466 https://reactome.org/PathwayBrowser/#/R-MMU-5213466 RIPK3 is phosphorylated IEA Mus musculus 71219 R-MMU-9674093 https://reactome.org/PathwayBrowser/#/R-MMU-9674093 PDGFRs bind type I TKI IEA Mus musculus 71219 R-MMU-9693978 https://reactome.org/PathwayBrowser/#/R-MMU-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Mus musculus 71219 R-RNO-389083 https://reactome.org/PathwayBrowser/#/R-RNO-389083 Autophosphorylation of PDGF alpha receptors IEA Rattus norvegicus 71219 R-RNO-5213464 https://reactome.org/PathwayBrowser/#/R-RNO-5213464 RIPK1 is phosphorylated IEA Rattus norvegicus 71219 R-RNO-5213466 https://reactome.org/PathwayBrowser/#/R-RNO-5213466 RIPK3 is phosphorylated IEA Rattus norvegicus 71219 R-RNO-9674093 https://reactome.org/PathwayBrowser/#/R-RNO-9674093 PDGFRs bind type I TKI IEA Rattus norvegicus 71219 R-RNO-9693978 https://reactome.org/PathwayBrowser/#/R-RNO-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Rattus norvegicus 71219 R-SSC-389083 https://reactome.org/PathwayBrowser/#/R-SSC-389083 Autophosphorylation of PDGF alpha receptors IEA Sus scrofa 71219 R-SSC-5213464 https://reactome.org/PathwayBrowser/#/R-SSC-5213464 RIPK1 is phosphorylated IEA Sus scrofa 71219 R-SSC-5213466 https://reactome.org/PathwayBrowser/#/R-SSC-5213466 RIPK3 is phosphorylated IEA Sus scrofa 71219 R-SSC-9674093 https://reactome.org/PathwayBrowser/#/R-SSC-9674093 PDGFRs bind type I TKI IEA Sus scrofa 71219 R-SSC-9693978 https://reactome.org/PathwayBrowser/#/R-SSC-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Sus scrofa 71253 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 71253 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 71253 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 71253 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 71253 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 71253 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 71253 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 71253 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 71253 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 71253 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 71253 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 71253 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 71253 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 71253 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 71253 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 71253 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 71253 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 71253 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 71253 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 71253 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 71253 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 71253 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 71253 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 71253 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 71253 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 71253 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 71253 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 71253 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 71259 R-HSA-2408542 https://reactome.org/PathwayBrowser/#/R-HSA-2408542 GSSeSG is reduced to GSSeH and GSH by GSR IEA Homo sapiens 71259 R-HSA-2408556 https://reactome.org/PathwayBrowser/#/R-HSA-2408556 SeO3(2-) combines with GSH to form GSSeSG and GSSG IEA Homo sapiens 71259 R-RNO-2408514 https://reactome.org/PathwayBrowser/#/R-RNO-2408514 GSSeSG is reduced to GSSeH and GSH by Gsr TAS Rattus norvegicus 71259 R-RNO-2408553 https://reactome.org/PathwayBrowser/#/R-RNO-2408553 SeO3(2-) combines with GSH to form GSSeSG and GSSG TAS Rattus norvegicus 71361 R-BTA-2395965 https://reactome.org/PathwayBrowser/#/R-BTA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Bos taurus 71361 R-BTA-9731228 https://reactome.org/PathwayBrowser/#/R-BTA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Bos taurus 71361 R-CEL-2395965 https://reactome.org/PathwayBrowser/#/R-CEL-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Caenorhabditis elegans 71361 R-CFA-2395965 https://reactome.org/PathwayBrowser/#/R-CFA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Canis familiaris 71361 R-CFA-9731228 https://reactome.org/PathwayBrowser/#/R-CFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Canis familiaris 71361 R-DME-2395965 https://reactome.org/PathwayBrowser/#/R-DME-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Drosophila melanogaster 71361 R-DRE-2395965 https://reactome.org/PathwayBrowser/#/R-DRE-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Danio rerio 71361 R-DRE-9731228 https://reactome.org/PathwayBrowser/#/R-DRE-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Danio rerio 71361 R-GGA-9731228 https://reactome.org/PathwayBrowser/#/R-GGA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Gallus gallus 71361 R-HSA-2395965 https://reactome.org/PathwayBrowser/#/R-HSA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP TAS Homo sapiens 71361 R-HSA-9731228 https://reactome.org/PathwayBrowser/#/R-HSA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP TAS Homo sapiens 71361 R-MMU-2395965 https://reactome.org/PathwayBrowser/#/R-MMU-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Mus musculus 71361 R-MMU-9731228 https://reactome.org/PathwayBrowser/#/R-MMU-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Mus musculus 71361 R-PFA-9731228 https://reactome.org/PathwayBrowser/#/R-PFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Plasmodium falciparum 71361 R-RNO-2395965 https://reactome.org/PathwayBrowser/#/R-RNO-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Rattus norvegicus 71361 R-RNO-9731228 https://reactome.org/PathwayBrowser/#/R-RNO-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Rattus norvegicus 71361 R-SSC-2395965 https://reactome.org/PathwayBrowser/#/R-SSC-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Sus scrofa 71361 R-SSC-9731228 https://reactome.org/PathwayBrowser/#/R-SSC-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Sus scrofa 71361 R-XTR-2395965 https://reactome.org/PathwayBrowser/#/R-XTR-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Xenopus tropicalis 71361 R-XTR-9731228 https://reactome.org/PathwayBrowser/#/R-XTR-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Xenopus tropicalis 71362 R-BTA-2395965 https://reactome.org/PathwayBrowser/#/R-BTA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Bos taurus 71362 R-CEL-2395965 https://reactome.org/PathwayBrowser/#/R-CEL-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Caenorhabditis elegans 71362 R-CFA-2395965 https://reactome.org/PathwayBrowser/#/R-CFA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Canis familiaris 71362 R-DME-2395965 https://reactome.org/PathwayBrowser/#/R-DME-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Drosophila melanogaster 71362 R-DRE-2395965 https://reactome.org/PathwayBrowser/#/R-DRE-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Danio rerio 71362 R-HSA-2395965 https://reactome.org/PathwayBrowser/#/R-HSA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP TAS Homo sapiens 71362 R-MMU-2395965 https://reactome.org/PathwayBrowser/#/R-MMU-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Mus musculus 71362 R-RNO-2395965 https://reactome.org/PathwayBrowser/#/R-RNO-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Rattus norvegicus 71362 R-SSC-2395965 https://reactome.org/PathwayBrowser/#/R-SSC-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Sus scrofa 71362 R-XTR-2395965 https://reactome.org/PathwayBrowser/#/R-XTR-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Xenopus tropicalis 71395 R-BTA-2395872 https://reactome.org/PathwayBrowser/#/R-BTA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Bos taurus 71395 R-CFA-2395872 https://reactome.org/PathwayBrowser/#/R-CFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Canis familiaris 71395 R-DRE-2395872 https://reactome.org/PathwayBrowser/#/R-DRE-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Danio rerio 71395 R-GGA-2395872 https://reactome.org/PathwayBrowser/#/R-GGA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Gallus gallus 71395 R-HSA-2395872 https://reactome.org/PathwayBrowser/#/R-HSA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP TAS Homo sapiens 71395 R-MMU-2395872 https://reactome.org/PathwayBrowser/#/R-MMU-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Mus musculus 71395 R-PFA-2395872 https://reactome.org/PathwayBrowser/#/R-PFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Plasmodium falciparum 71395 R-RNO-2395872 https://reactome.org/PathwayBrowser/#/R-RNO-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Rattus norvegicus 71395 R-SSC-2395872 https://reactome.org/PathwayBrowser/#/R-SSC-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Sus scrofa 71395 R-XTR-2395872 https://reactome.org/PathwayBrowser/#/R-XTR-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Xenopus tropicalis 71406 R-BTA-209903 https://reactome.org/PathwayBrowser/#/R-BTA-209903 Noradrenaline is converted to adrenaline IEA Bos taurus 71406 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 71406 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 71406 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 71406 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 71406 R-BTA-390663 https://reactome.org/PathwayBrowser/#/R-BTA-390663 ADRA2A,B,C bind ADR,NAd IEA Bos taurus 71406 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 71406 R-BTA-400071 https://reactome.org/PathwayBrowser/#/R-BTA-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Bos taurus 71406 R-BTA-400092 https://reactome.org/PathwayBrowser/#/R-BTA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Bos taurus 71406 R-BTA-444160 https://reactome.org/PathwayBrowser/#/R-BTA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Bos taurus 71406 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 71406 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 71406 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 71406 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 71406 R-BTA-5684862 https://reactome.org/PathwayBrowser/#/R-BTA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Bos taurus 71406 R-BTA-727740 https://reactome.org/PathwayBrowser/#/R-BTA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 71406 R-BTA-727768 https://reactome.org/PathwayBrowser/#/R-BTA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 71406 R-BTA-749446 https://reactome.org/PathwayBrowser/#/R-BTA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Bos taurus 71406 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 71406 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 71406 R-BTA-749453 https://reactome.org/PathwayBrowser/#/R-BTA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Bos taurus 71406 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 71406 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 71406 R-BTA-751019 https://reactome.org/PathwayBrowser/#/R-BTA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Bos taurus 71406 R-BTA-751024 https://reactome.org/PathwayBrowser/#/R-BTA-751024 The Ligand:GPCR:Gz complex dissociates IEA Bos taurus 71406 R-BTA-751027 https://reactome.org/PathwayBrowser/#/R-BTA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Bos taurus 71406 R-BTA-751029 https://reactome.org/PathwayBrowser/#/R-BTA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Bos taurus 71406 R-BTA-8851797 https://reactome.org/PathwayBrowser/#/R-BTA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Bos taurus 71406 R-BTA-8852167 https://reactome.org/PathwayBrowser/#/R-BTA-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Bos taurus 71406 R-BTA-8866269 https://reactome.org/PathwayBrowser/#/R-BTA-8866269 ARRB bind GPCRs IEA Bos taurus 71406 R-BTA-8866283 https://reactome.org/PathwayBrowser/#/R-BTA-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Bos taurus 71406 R-BTA-8867754 https://reactome.org/PathwayBrowser/#/R-BTA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Bos taurus 71406 R-BTA-8867756 https://reactome.org/PathwayBrowser/#/R-BTA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Bos taurus 71406 R-BTA-8868071 https://reactome.org/PathwayBrowser/#/R-BTA-8868071 Clathrin recruits PIK3C2A IEA Bos taurus 71406 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 71406 R-BTA-8868230 https://reactome.org/PathwayBrowser/#/R-BTA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Bos taurus 71406 R-BTA-8868236 https://reactome.org/PathwayBrowser/#/R-BTA-8868236 BAR domain proteins recruit dynamin IEA Bos taurus 71406 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 71406 R-BTA-8868651 https://reactome.org/PathwayBrowser/#/R-BTA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Bos taurus 71406 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 71406 R-BTA-8868659 https://reactome.org/PathwayBrowser/#/R-BTA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Bos taurus 71406 R-BTA-8868660 https://reactome.org/PathwayBrowser/#/R-BTA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Bos taurus 71406 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 71406 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 71406 R-BTA-8871194 https://reactome.org/PathwayBrowser/#/R-BTA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Bos taurus 71406 R-BTA-8982641 https://reactome.org/PathwayBrowser/#/R-BTA-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Bos taurus 71406 R-BTA-8982645 https://reactome.org/PathwayBrowser/#/R-BTA-8982645 GRKs bind ADRB2:Catecholamine IEA Bos taurus 71406 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 71406 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 71406 R-CEL-209903 https://reactome.org/PathwayBrowser/#/R-CEL-209903 Noradrenaline is converted to adrenaline IEA Caenorhabditis elegans 71406 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 71406 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 71406 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 71406 R-CEL-390663 https://reactome.org/PathwayBrowser/#/R-CEL-390663 ADRA2A,B,C bind ADR,NAd IEA Caenorhabditis elegans 71406 R-CEL-400071 https://reactome.org/PathwayBrowser/#/R-CEL-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Caenorhabditis elegans 71406 R-CEL-400092 https://reactome.org/PathwayBrowser/#/R-CEL-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Caenorhabditis elegans 71406 R-CEL-444160 https://reactome.org/PathwayBrowser/#/R-CEL-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Caenorhabditis elegans 71406 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 71406 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 71406 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 71406 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 71406 R-CEL-749446 https://reactome.org/PathwayBrowser/#/R-CEL-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Caenorhabditis elegans 71406 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 71406 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 71406 R-CEL-749453 https://reactome.org/PathwayBrowser/#/R-CEL-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Caenorhabditis elegans 71406 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 71406 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 71406 R-CEL-751019 https://reactome.org/PathwayBrowser/#/R-CEL-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Caenorhabditis elegans 71406 R-CEL-751024 https://reactome.org/PathwayBrowser/#/R-CEL-751024 The Ligand:GPCR:Gz complex dissociates IEA Caenorhabditis elegans 71406 R-CEL-751027 https://reactome.org/PathwayBrowser/#/R-CEL-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Caenorhabditis elegans 71406 R-CEL-751029 https://reactome.org/PathwayBrowser/#/R-CEL-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Caenorhabditis elegans 71406 R-CFA-209903 https://reactome.org/PathwayBrowser/#/R-CFA-209903 Noradrenaline is converted to adrenaline IEA Canis familiaris 71406 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 71406 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 71406 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 71406 R-CFA-390663 https://reactome.org/PathwayBrowser/#/R-CFA-390663 ADRA2A,B,C bind ADR,NAd IEA Canis familiaris 71406 R-CFA-400071 https://reactome.org/PathwayBrowser/#/R-CFA-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Canis familiaris 71406 R-CFA-400092 https://reactome.org/PathwayBrowser/#/R-CFA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Canis familiaris 71406 R-CFA-444160 https://reactome.org/PathwayBrowser/#/R-CFA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Canis familiaris 71406 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 71406 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 71406 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 71406 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 71406 R-CFA-5684862 https://reactome.org/PathwayBrowser/#/R-CFA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Canis familiaris 71406 R-CFA-727740 https://reactome.org/PathwayBrowser/#/R-CFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 71406 R-CFA-727768 https://reactome.org/PathwayBrowser/#/R-CFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 71406 R-CFA-749446 https://reactome.org/PathwayBrowser/#/R-CFA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Canis familiaris 71406 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 71406 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 71406 R-CFA-749453 https://reactome.org/PathwayBrowser/#/R-CFA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Canis familiaris 71406 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 71406 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 71406 R-CFA-751019 https://reactome.org/PathwayBrowser/#/R-CFA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Canis familiaris 71406 R-CFA-751024 https://reactome.org/PathwayBrowser/#/R-CFA-751024 The Ligand:GPCR:Gz complex dissociates IEA Canis familiaris 71406 R-CFA-751027 https://reactome.org/PathwayBrowser/#/R-CFA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Canis familiaris 71406 R-CFA-751029 https://reactome.org/PathwayBrowser/#/R-CFA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Canis familiaris 71406 R-CFA-8851797 https://reactome.org/PathwayBrowser/#/R-CFA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Canis familiaris 71406 R-CFA-8852167 https://reactome.org/PathwayBrowser/#/R-CFA-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Canis familiaris 71406 R-CFA-8866269 https://reactome.org/PathwayBrowser/#/R-CFA-8866269 ARRB bind GPCRs IEA Canis familiaris 71406 R-CFA-8866283 https://reactome.org/PathwayBrowser/#/R-CFA-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Canis familiaris 71406 R-CFA-8867754 https://reactome.org/PathwayBrowser/#/R-CFA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Canis familiaris 71406 R-CFA-8867756 https://reactome.org/PathwayBrowser/#/R-CFA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Canis familiaris 71406 R-CFA-8868071 https://reactome.org/PathwayBrowser/#/R-CFA-8868071 Clathrin recruits PIK3C2A IEA Canis familiaris 71406 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 71406 R-CFA-8868230 https://reactome.org/PathwayBrowser/#/R-CFA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Canis familiaris 71406 R-CFA-8868236 https://reactome.org/PathwayBrowser/#/R-CFA-8868236 BAR domain proteins recruit dynamin IEA Canis familiaris 71406 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 71406 R-CFA-8868651 https://reactome.org/PathwayBrowser/#/R-CFA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Canis familiaris 71406 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 71406 R-CFA-8868659 https://reactome.org/PathwayBrowser/#/R-CFA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Canis familiaris 71406 R-CFA-8868660 https://reactome.org/PathwayBrowser/#/R-CFA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Canis familiaris 71406 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 71406 R-CFA-8871193 https://reactome.org/PathwayBrowser/#/R-CFA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Canis familiaris 71406 R-CFA-8871194 https://reactome.org/PathwayBrowser/#/R-CFA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Canis familiaris 71406 R-CFA-8982641 https://reactome.org/PathwayBrowser/#/R-CFA-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Canis familiaris 71406 R-CFA-8982645 https://reactome.org/PathwayBrowser/#/R-CFA-8982645 GRKs bind ADRB2:Catecholamine IEA Canis familiaris 71406 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 71406 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 71406 R-DDI-727740 https://reactome.org/PathwayBrowser/#/R-DDI-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 71406 R-DDI-727768 https://reactome.org/PathwayBrowser/#/R-DDI-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 71406 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 71406 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 71406 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 71406 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 71406 R-DME-390663 https://reactome.org/PathwayBrowser/#/R-DME-390663 ADRA2A,B,C bind ADR,NAd IEA Drosophila melanogaster 71406 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 71406 R-DME-400071 https://reactome.org/PathwayBrowser/#/R-DME-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Drosophila melanogaster 71406 R-DME-400092 https://reactome.org/PathwayBrowser/#/R-DME-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Drosophila melanogaster 71406 R-DME-444160 https://reactome.org/PathwayBrowser/#/R-DME-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Drosophila melanogaster 71406 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 71406 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 71406 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 71406 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 71406 R-DME-727740 https://reactome.org/PathwayBrowser/#/R-DME-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 71406 R-DME-727768 https://reactome.org/PathwayBrowser/#/R-DME-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 71406 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 71406 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 71406 R-DME-749453 https://reactome.org/PathwayBrowser/#/R-DME-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Drosophila melanogaster 71406 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 71406 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 71406 R-DME-751019 https://reactome.org/PathwayBrowser/#/R-DME-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Drosophila melanogaster 71406 R-DME-751027 https://reactome.org/PathwayBrowser/#/R-DME-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Drosophila melanogaster 71406 R-DME-751029 https://reactome.org/PathwayBrowser/#/R-DME-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Drosophila melanogaster 71406 R-DME-8851797 https://reactome.org/PathwayBrowser/#/R-DME-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Drosophila melanogaster 71406 R-DME-8852167 https://reactome.org/PathwayBrowser/#/R-DME-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Drosophila melanogaster 71406 R-DME-8866269 https://reactome.org/PathwayBrowser/#/R-DME-8866269 ARRB bind GPCRs IEA Drosophila melanogaster 71406 R-DME-8866283 https://reactome.org/PathwayBrowser/#/R-DME-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Drosophila melanogaster 71406 R-DME-8867754 https://reactome.org/PathwayBrowser/#/R-DME-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Drosophila melanogaster 71406 R-DME-8867756 https://reactome.org/PathwayBrowser/#/R-DME-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Drosophila melanogaster 71406 R-DME-8868071 https://reactome.org/PathwayBrowser/#/R-DME-8868071 Clathrin recruits PIK3C2A IEA Drosophila melanogaster 71406 R-DME-8868072 https://reactome.org/PathwayBrowser/#/R-DME-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Drosophila melanogaster 71406 R-DME-8868236 https://reactome.org/PathwayBrowser/#/R-DME-8868236 BAR domain proteins recruit dynamin IEA Drosophila melanogaster 71406 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster 71406 R-DME-8868651 https://reactome.org/PathwayBrowser/#/R-DME-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Drosophila melanogaster 71406 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster 71406 R-DME-8868660 https://reactome.org/PathwayBrowser/#/R-DME-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Drosophila melanogaster 71406 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster 71406 R-DME-8871194 https://reactome.org/PathwayBrowser/#/R-DME-8871194 RAB5 and GAPVD1 bind AP-2 IEA Drosophila melanogaster 71406 R-DME-8982641 https://reactome.org/PathwayBrowser/#/R-DME-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Drosophila melanogaster 71406 R-DME-8982645 https://reactome.org/PathwayBrowser/#/R-DME-8982645 GRKs bind ADRB2:Catecholamine IEA Drosophila melanogaster 71406 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 71406 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 71406 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 71406 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 71406 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 71406 R-DRE-390663 https://reactome.org/PathwayBrowser/#/R-DRE-390663 ADRA2A,B,C bind ADR,NAd IEA Danio rerio 71406 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 71406 R-DRE-400071 https://reactome.org/PathwayBrowser/#/R-DRE-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Danio rerio 71406 R-DRE-400092 https://reactome.org/PathwayBrowser/#/R-DRE-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Danio rerio 71406 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 71406 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 71406 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 71406 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 71406 R-DRE-727740 https://reactome.org/PathwayBrowser/#/R-DRE-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 71406 R-DRE-727768 https://reactome.org/PathwayBrowser/#/R-DRE-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 71406 R-DRE-751029 https://reactome.org/PathwayBrowser/#/R-DRE-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Danio rerio 71406 R-DRE-8852167 https://reactome.org/PathwayBrowser/#/R-DRE-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Danio rerio 71406 R-DRE-8866269 https://reactome.org/PathwayBrowser/#/R-DRE-8866269 ARRB bind GPCRs IEA Danio rerio 71406 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 71406 R-GGA-209903 https://reactome.org/PathwayBrowser/#/R-GGA-209903 Noradrenaline is converted to adrenaline IEA Gallus gallus 71406 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 71406 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 71406 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 71406 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 71406 R-GGA-390663 https://reactome.org/PathwayBrowser/#/R-GGA-390663 ADRA2A,B,C bind ADR,NAd IEA Gallus gallus 71406 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 71406 R-GGA-400071 https://reactome.org/PathwayBrowser/#/R-GGA-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Gallus gallus 71406 R-GGA-444160 https://reactome.org/PathwayBrowser/#/R-GGA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Gallus gallus 71406 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 71406 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 71406 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 71406 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 71406 R-GGA-5684862 https://reactome.org/PathwayBrowser/#/R-GGA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Gallus gallus 71406 R-GGA-727740 https://reactome.org/PathwayBrowser/#/R-GGA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 71406 R-GGA-727768 https://reactome.org/PathwayBrowser/#/R-GGA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 71406 R-GGA-749446 https://reactome.org/PathwayBrowser/#/R-GGA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Gallus gallus 71406 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 71406 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 71406 R-GGA-749453 https://reactome.org/PathwayBrowser/#/R-GGA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Gallus gallus 71406 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 71406 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 71406 R-GGA-751019 https://reactome.org/PathwayBrowser/#/R-GGA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Gallus gallus 71406 R-GGA-751024 https://reactome.org/PathwayBrowser/#/R-GGA-751024 The Ligand:GPCR:Gz complex dissociates IEA Gallus gallus 71406 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus 71406 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus 71406 R-GGA-8851797 https://reactome.org/PathwayBrowser/#/R-GGA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Gallus gallus 71406 R-GGA-8982641 https://reactome.org/PathwayBrowser/#/R-GGA-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Gallus gallus 71406 R-GGA-8982645 https://reactome.org/PathwayBrowser/#/R-GGA-8982645 GRKs bind ADRB2:Catecholamine IEA Gallus gallus 71406 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 71406 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 71406 R-HSA-209903 https://reactome.org/PathwayBrowser/#/R-HSA-209903 Noradrenaline is converted to adrenaline TAS Homo sapiens 71406 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 71406 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 71406 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 71406 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 71406 R-HSA-390663 https://reactome.org/PathwayBrowser/#/R-HSA-390663 ADRA2A,B,C bind ADR,NAd TAS Homo sapiens 71406 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 71406 R-HSA-400071 https://reactome.org/PathwayBrowser/#/R-HSA-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline TAS Homo sapiens 71406 R-HSA-400092 https://reactome.org/PathwayBrowser/#/R-HSA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins TAS Homo sapiens 71406 R-HSA-444160 https://reactome.org/PathwayBrowser/#/R-HSA-444160 VMAT1/2 can mediate the transport of biogenic amines TAS Homo sapiens 71406 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 71406 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 71406 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 71406 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 71406 R-HSA-5684862 https://reactome.org/PathwayBrowser/#/R-HSA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. TAS Homo sapiens 71406 R-HSA-727740 https://reactome.org/PathwayBrowser/#/R-HSA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 71406 R-HSA-727768 https://reactome.org/PathwayBrowser/#/R-HSA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 71406 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 71406 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 71406 R-HSA-749446 https://reactome.org/PathwayBrowser/#/R-HSA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz TAS Homo sapiens 71406 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 71406 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 71406 R-HSA-749453 https://reactome.org/PathwayBrowser/#/R-HSA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz TAS Homo sapiens 71406 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 71406 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 71406 R-HSA-751019 https://reactome.org/PathwayBrowser/#/R-HSA-751019 The Ligand:GPCR:G12/13 complex dissociates TAS Homo sapiens 71406 R-HSA-751024 https://reactome.org/PathwayBrowser/#/R-HSA-751024 The Ligand:GPCR:Gz complex dissociates TAS Homo sapiens 71406 R-HSA-751027 https://reactome.org/PathwayBrowser/#/R-HSA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 TAS Homo sapiens 71406 R-HSA-751029 https://reactome.org/PathwayBrowser/#/R-HSA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 TAS Homo sapiens 71406 R-HSA-8851797 https://reactome.org/PathwayBrowser/#/R-HSA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated TAS Homo sapiens 71406 R-HSA-8852167 https://reactome.org/PathwayBrowser/#/R-HSA-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 TAS Homo sapiens 71406 R-HSA-8866269 https://reactome.org/PathwayBrowser/#/R-HSA-8866269 ARRB bind GPCRs TAS Homo sapiens 71406 R-HSA-8866283 https://reactome.org/PathwayBrowser/#/R-HSA-8866283 ARBB recruits GPCRs into clathrin-coated pits TAS Homo sapiens 71406 R-HSA-8867754 https://reactome.org/PathwayBrowser/#/R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit TAS Homo sapiens 71406 R-HSA-8867756 https://reactome.org/PathwayBrowser/#/R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit TAS Homo sapiens 71406 R-HSA-8868071 https://reactome.org/PathwayBrowser/#/R-HSA-8868071 Clathrin recruits PIK3C2A TAS Homo sapiens 71406 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 71406 R-HSA-8868230 https://reactome.org/PathwayBrowser/#/R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery TAS Homo sapiens 71406 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 71406 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 71406 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 71406 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 71406 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 71406 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 71406 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 71406 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 71406 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 71406 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 71406 R-HSA-8982641 https://reactome.org/PathwayBrowser/#/R-HSA-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 TAS Homo sapiens 71406 R-HSA-8982645 https://reactome.org/PathwayBrowser/#/R-HSA-8982645 GRKs bind ADRB2:Catecholamine TAS Homo sapiens 71406 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 71406 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 71406 R-MMU-209903 https://reactome.org/PathwayBrowser/#/R-MMU-209903 Noradrenaline is converted to adrenaline IEA Mus musculus 71406 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 71406 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 71406 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 71406 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 71406 R-MMU-390663 https://reactome.org/PathwayBrowser/#/R-MMU-390663 ADRA2A,B,C bind ADR,NAd IEA Mus musculus 71406 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 71406 R-MMU-400071 https://reactome.org/PathwayBrowser/#/R-MMU-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Mus musculus 71406 R-MMU-400092 https://reactome.org/PathwayBrowser/#/R-MMU-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Mus musculus 71406 R-MMU-444160 https://reactome.org/PathwayBrowser/#/R-MMU-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Mus musculus 71406 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 71406 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 71406 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 71406 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 71406 R-MMU-5684862 https://reactome.org/PathwayBrowser/#/R-MMU-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Mus musculus 71406 R-MMU-727740 https://reactome.org/PathwayBrowser/#/R-MMU-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 71406 R-MMU-727768 https://reactome.org/PathwayBrowser/#/R-MMU-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 71406 R-MMU-749446 https://reactome.org/PathwayBrowser/#/R-MMU-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Mus musculus 71406 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 71406 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 71406 R-MMU-749453 https://reactome.org/PathwayBrowser/#/R-MMU-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Mus musculus 71406 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 71406 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 71406 R-MMU-751019 https://reactome.org/PathwayBrowser/#/R-MMU-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Mus musculus 71406 R-MMU-751024 https://reactome.org/PathwayBrowser/#/R-MMU-751024 The Ligand:GPCR:Gz complex dissociates IEA Mus musculus 71406 R-MMU-751027 https://reactome.org/PathwayBrowser/#/R-MMU-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Mus musculus 71406 R-MMU-751029 https://reactome.org/PathwayBrowser/#/R-MMU-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Mus musculus 71406 R-MMU-8851797 https://reactome.org/PathwayBrowser/#/R-MMU-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Mus musculus 71406 R-MMU-8852167 https://reactome.org/PathwayBrowser/#/R-MMU-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Mus musculus 71406 R-MMU-8866269 https://reactome.org/PathwayBrowser/#/R-MMU-8866269 ARRB bind GPCRs IEA Mus musculus 71406 R-MMU-8866283 https://reactome.org/PathwayBrowser/#/R-MMU-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Mus musculus 71406 R-MMU-8867754 https://reactome.org/PathwayBrowser/#/R-MMU-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Mus musculus 71406 R-MMU-8867756 https://reactome.org/PathwayBrowser/#/R-MMU-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Mus musculus 71406 R-MMU-8868071 https://reactome.org/PathwayBrowser/#/R-MMU-8868071 Clathrin recruits PIK3C2A IEA Mus musculus 71406 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 71406 R-MMU-8868236 https://reactome.org/PathwayBrowser/#/R-MMU-8868236 BAR domain proteins recruit dynamin IEA Mus musculus 71406 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 71406 R-MMU-8868651 https://reactome.org/PathwayBrowser/#/R-MMU-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Mus musculus 71406 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 71406 R-MMU-8868659 https://reactome.org/PathwayBrowser/#/R-MMU-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Mus musculus 71406 R-MMU-8868660 https://reactome.org/PathwayBrowser/#/R-MMU-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Mus musculus 71406 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 71406 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 71406 R-MMU-8871194 https://reactome.org/PathwayBrowser/#/R-MMU-8871194 RAB5 and GAPVD1 bind AP-2 IEA Mus musculus 71406 R-MMU-8982641 https://reactome.org/PathwayBrowser/#/R-MMU-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Mus musculus 71406 R-MMU-8982645 https://reactome.org/PathwayBrowser/#/R-MMU-8982645 GRKs bind ADRB2:Catecholamine IEA Mus musculus 71406 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 71406 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 71406 R-PFA-727740 https://reactome.org/PathwayBrowser/#/R-PFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 71406 R-PFA-727768 https://reactome.org/PathwayBrowser/#/R-PFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 71406 R-RNO-209903 https://reactome.org/PathwayBrowser/#/R-RNO-209903 Noradrenaline is converted to adrenaline IEA Rattus norvegicus 71406 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 71406 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 71406 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 71406 R-RNO-390663 https://reactome.org/PathwayBrowser/#/R-RNO-390663 ADRA2A,B,C bind ADR,NAd IEA Rattus norvegicus 71406 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 71406 R-RNO-400071 https://reactome.org/PathwayBrowser/#/R-RNO-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Rattus norvegicus 71406 R-RNO-400092 https://reactome.org/PathwayBrowser/#/R-RNO-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Rattus norvegicus 71406 R-RNO-444160 https://reactome.org/PathwayBrowser/#/R-RNO-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Rattus norvegicus 71406 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 71406 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 71406 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 71406 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 71406 R-RNO-5684862 https://reactome.org/PathwayBrowser/#/R-RNO-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Rattus norvegicus 71406 R-RNO-727740 https://reactome.org/PathwayBrowser/#/R-RNO-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 71406 R-RNO-727768 https://reactome.org/PathwayBrowser/#/R-RNO-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 71406 R-RNO-749453 https://reactome.org/PathwayBrowser/#/R-RNO-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Rattus norvegicus 71406 R-RNO-751029 https://reactome.org/PathwayBrowser/#/R-RNO-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Rattus norvegicus 71406 R-RNO-8851797 https://reactome.org/PathwayBrowser/#/R-RNO-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Rattus norvegicus 71406 R-RNO-8852167 https://reactome.org/PathwayBrowser/#/R-RNO-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Rattus norvegicus 71406 R-RNO-8866269 https://reactome.org/PathwayBrowser/#/R-RNO-8866269 ARRB bind GPCRs IEA Rattus norvegicus 71406 R-RNO-8866283 https://reactome.org/PathwayBrowser/#/R-RNO-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Rattus norvegicus 71406 R-RNO-8867754 https://reactome.org/PathwayBrowser/#/R-RNO-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Rattus norvegicus 71406 R-RNO-8867756 https://reactome.org/PathwayBrowser/#/R-RNO-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Rattus norvegicus 71406 R-RNO-8868071 https://reactome.org/PathwayBrowser/#/R-RNO-8868071 Clathrin recruits PIK3C2A IEA Rattus norvegicus 71406 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 71406 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus 71406 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 71406 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus 71406 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 71406 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus 71406 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus 71406 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 71406 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 71406 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus 71406 R-RNO-8982641 https://reactome.org/PathwayBrowser/#/R-RNO-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Rattus norvegicus 71406 R-RNO-8982645 https://reactome.org/PathwayBrowser/#/R-RNO-8982645 GRKs bind ADRB2:Catecholamine IEA Rattus norvegicus 71406 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 71406 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 71406 R-SPO-444160 https://reactome.org/PathwayBrowser/#/R-SPO-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Schizosaccharomyces pombe 71406 R-SSC-209903 https://reactome.org/PathwayBrowser/#/R-SSC-209903 Noradrenaline is converted to adrenaline IEA Sus scrofa 71406 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 71406 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 71406 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 71406 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 71406 R-SSC-390663 https://reactome.org/PathwayBrowser/#/R-SSC-390663 ADRA2A,B,C bind ADR,NAd IEA Sus scrofa 71406 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 71406 R-SSC-400071 https://reactome.org/PathwayBrowser/#/R-SSC-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Sus scrofa 71406 R-SSC-400092 https://reactome.org/PathwayBrowser/#/R-SSC-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Sus scrofa 71406 R-SSC-444160 https://reactome.org/PathwayBrowser/#/R-SSC-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Sus scrofa 71406 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 71406 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 71406 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 71406 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 71406 R-SSC-5684862 https://reactome.org/PathwayBrowser/#/R-SSC-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Sus scrofa 71406 R-SSC-727740 https://reactome.org/PathwayBrowser/#/R-SSC-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 71406 R-SSC-727768 https://reactome.org/PathwayBrowser/#/R-SSC-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 71406 R-SSC-749446 https://reactome.org/PathwayBrowser/#/R-SSC-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Sus scrofa 71406 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 71406 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 71406 R-SSC-749453 https://reactome.org/PathwayBrowser/#/R-SSC-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Sus scrofa 71406 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 71406 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 71406 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa 71406 R-SSC-751024 https://reactome.org/PathwayBrowser/#/R-SSC-751024 The Ligand:GPCR:Gz complex dissociates IEA Sus scrofa 71406 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa 71406 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa 71406 R-SSC-8851797 https://reactome.org/PathwayBrowser/#/R-SSC-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Sus scrofa 71406 R-SSC-8852167 https://reactome.org/PathwayBrowser/#/R-SSC-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Sus scrofa 71406 R-SSC-8866269 https://reactome.org/PathwayBrowser/#/R-SSC-8866269 ARRB bind GPCRs IEA Sus scrofa 71406 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa 71406 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa 71406 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa 71406 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa 71406 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 71406 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa 71406 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa 71406 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 71406 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa 71406 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 71406 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa 71406 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa 71406 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 71406 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 71406 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa 71406 R-SSC-8982641 https://reactome.org/PathwayBrowser/#/R-SSC-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Sus scrofa 71406 R-SSC-8982645 https://reactome.org/PathwayBrowser/#/R-SSC-8982645 GRKs bind ADRB2:Catecholamine IEA Sus scrofa 71406 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 71406 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 71406 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 71406 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 71406 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 71406 R-XTR-390663 https://reactome.org/PathwayBrowser/#/R-XTR-390663 ADRA2A,B,C bind ADR,NAd IEA Xenopus tropicalis 71406 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 71406 R-XTR-400071 https://reactome.org/PathwayBrowser/#/R-XTR-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Xenopus tropicalis 71406 R-XTR-400092 https://reactome.org/PathwayBrowser/#/R-XTR-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Xenopus tropicalis 71406 R-XTR-444160 https://reactome.org/PathwayBrowser/#/R-XTR-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Xenopus tropicalis 71406 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 71406 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 71406 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 71406 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 71406 R-XTR-749446 https://reactome.org/PathwayBrowser/#/R-XTR-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Xenopus tropicalis 71406 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 71406 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 71406 R-XTR-749453 https://reactome.org/PathwayBrowser/#/R-XTR-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Xenopus tropicalis 71406 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 71406 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 71406 R-XTR-751019 https://reactome.org/PathwayBrowser/#/R-XTR-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Xenopus tropicalis 71406 R-XTR-751024 https://reactome.org/PathwayBrowser/#/R-XTR-751024 The Ligand:GPCR:Gz complex dissociates IEA Xenopus tropicalis 71406 R-XTR-751027 https://reactome.org/PathwayBrowser/#/R-XTR-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Xenopus tropicalis 71406 R-XTR-751029 https://reactome.org/PathwayBrowser/#/R-XTR-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Xenopus tropicalis 71406 R-XTR-8851797 https://reactome.org/PathwayBrowser/#/R-XTR-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Xenopus tropicalis 71406 R-XTR-8852167 https://reactome.org/PathwayBrowser/#/R-XTR-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Xenopus tropicalis 71406 R-XTR-8866269 https://reactome.org/PathwayBrowser/#/R-XTR-8866269 ARRB bind GPCRs IEA Xenopus tropicalis 71406 R-XTR-8982641 https://reactome.org/PathwayBrowser/#/R-XTR-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Xenopus tropicalis 71406 R-XTR-8982645 https://reactome.org/PathwayBrowser/#/R-XTR-8982645 GRKs bind ADRB2:Catecholamine IEA Xenopus tropicalis 71406 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 71407 R-BTA-548814 https://reactome.org/PathwayBrowser/#/R-BTA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Bos taurus 71407 R-BTA-548818 https://reactome.org/PathwayBrowser/#/R-BTA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Bos taurus 71407 R-CEL-548814 https://reactome.org/PathwayBrowser/#/R-CEL-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Caenorhabditis elegans 71407 R-CEL-548818 https://reactome.org/PathwayBrowser/#/R-CEL-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Caenorhabditis elegans 71407 R-CFA-548814 https://reactome.org/PathwayBrowser/#/R-CFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Canis familiaris 71407 R-CFA-548818 https://reactome.org/PathwayBrowser/#/R-CFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Canis familiaris 71407 R-DDI-548814 https://reactome.org/PathwayBrowser/#/R-DDI-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Dictyostelium discoideum 71407 R-DDI-548818 https://reactome.org/PathwayBrowser/#/R-DDI-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Dictyostelium discoideum 71407 R-DME-548814 https://reactome.org/PathwayBrowser/#/R-DME-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Drosophila melanogaster 71407 R-DME-548818 https://reactome.org/PathwayBrowser/#/R-DME-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Drosophila melanogaster 71407 R-DRE-548814 https://reactome.org/PathwayBrowser/#/R-DRE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Danio rerio 71407 R-DRE-548818 https://reactome.org/PathwayBrowser/#/R-DRE-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Danio rerio 71407 R-GGA-548814 https://reactome.org/PathwayBrowser/#/R-GGA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Gallus gallus 71407 R-GGA-548818 https://reactome.org/PathwayBrowser/#/R-GGA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Gallus gallus 71407 R-HSA-548814 https://reactome.org/PathwayBrowser/#/R-HSA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA TAS Homo sapiens 71407 R-HSA-548818 https://reactome.org/PathwayBrowser/#/R-HSA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA TAS Homo sapiens 71407 R-MMU-548814 https://reactome.org/PathwayBrowser/#/R-MMU-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Mus musculus 71407 R-MMU-548818 https://reactome.org/PathwayBrowser/#/R-MMU-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Mus musculus 71407 R-PFA-548814 https://reactome.org/PathwayBrowser/#/R-PFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Plasmodium falciparum 71407 R-PFA-548818 https://reactome.org/PathwayBrowser/#/R-PFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Plasmodium falciparum 71407 R-RNO-548814 https://reactome.org/PathwayBrowser/#/R-RNO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Rattus norvegicus 71407 R-RNO-548818 https://reactome.org/PathwayBrowser/#/R-RNO-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Rattus norvegicus 71407 R-SCE-548814 https://reactome.org/PathwayBrowser/#/R-SCE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Saccharomyces cerevisiae 71407 R-SPO-548814 https://reactome.org/PathwayBrowser/#/R-SPO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Schizosaccharomyces pombe 71407 R-SSC-548814 https://reactome.org/PathwayBrowser/#/R-SSC-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Sus scrofa 71407 R-SSC-548818 https://reactome.org/PathwayBrowser/#/R-SSC-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Sus scrofa 71407 R-XTR-548814 https://reactome.org/PathwayBrowser/#/R-XTR-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Xenopus tropicalis 71407 R-XTR-548818 https://reactome.org/PathwayBrowser/#/R-XTR-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Xenopus tropicalis 71451 R-BTA-548815 https://reactome.org/PathwayBrowser/#/R-BTA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Bos taurus 71451 R-CFA-548815 https://reactome.org/PathwayBrowser/#/R-CFA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Canis familiaris 71451 R-DME-548815 https://reactome.org/PathwayBrowser/#/R-DME-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Drosophila melanogaster 71451 R-DRE-548815 https://reactome.org/PathwayBrowser/#/R-DRE-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Danio rerio 71451 R-GGA-548815 https://reactome.org/PathwayBrowser/#/R-GGA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Gallus gallus 71451 R-HSA-548815 https://reactome.org/PathwayBrowser/#/R-HSA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA TAS Homo sapiens 71451 R-MMU-548815 https://reactome.org/PathwayBrowser/#/R-MMU-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Mus musculus 71451 R-RNO-548815 https://reactome.org/PathwayBrowser/#/R-RNO-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Rattus norvegicus 71451 R-SSC-548815 https://reactome.org/PathwayBrowser/#/R-SSC-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Sus scrofa 71451 R-XTR-548815 https://reactome.org/PathwayBrowser/#/R-XTR-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Xenopus tropicalis 71464 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 71464 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 71464 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 71464 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 71464 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 71464 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 71464 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 71464 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 71466 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 71466 R-BTA-400509 https://reactome.org/PathwayBrowser/#/R-BTA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Bos taurus 71466 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 71466 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 71466 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 71466 R-CFA-400509 https://reactome.org/PathwayBrowser/#/R-CFA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Canis familiaris 71466 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 71466 R-GGA-400509 https://reactome.org/PathwayBrowser/#/R-GGA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Gallus gallus 71466 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 71466 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 71466 R-HSA-400509 https://reactome.org/PathwayBrowser/#/R-HSA-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells TAS Homo sapiens 71466 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 71466 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 71466 R-MMU-400509 https://reactome.org/PathwayBrowser/#/R-MMU-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Mus musculus 71466 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 71466 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 71466 R-RNO-400509 https://reactome.org/PathwayBrowser/#/R-RNO-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Rattus norvegicus 71466 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 71466 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 71466 R-SSC-400509 https://reactome.org/PathwayBrowser/#/R-SSC-400509 Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells IEA Sus scrofa 71466 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 71466 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 71501 R-BTA-3244643 https://reactome.org/PathwayBrowser/#/R-BTA-3244643 STING binds cyclic GMP-AMP IEA Bos taurus 71501 R-DME-3244643 https://reactome.org/PathwayBrowser/#/R-DME-3244643 STING binds cyclic GMP-AMP IEA Drosophila melanogaster 71501 R-DRE-3244643 https://reactome.org/PathwayBrowser/#/R-DRE-3244643 STING binds cyclic GMP-AMP IEA Danio rerio 71501 R-GGA-3244643 https://reactome.org/PathwayBrowser/#/R-GGA-3244643 STING binds cyclic GMP-AMP IEA Gallus gallus 71501 R-HSA-1834939 https://reactome.org/PathwayBrowser/#/R-HSA-1834939 STING recruits TBK1 and IRF3 TAS Homo sapiens 71501 R-HSA-3244614 https://reactome.org/PathwayBrowser/#/R-HSA-3244614 cGAS produces cyclic GMP-AMP TAS Homo sapiens 71501 R-HSA-3244643 https://reactome.org/PathwayBrowser/#/R-HSA-3244643 STING binds cyclic GMP-AMP TAS Homo sapiens 71501 R-MMU-3244643 https://reactome.org/PathwayBrowser/#/R-MMU-3244643 STING binds cyclic GMP-AMP IEA Mus musculus 71501 R-RNO-3244643 https://reactome.org/PathwayBrowser/#/R-RNO-3244643 STING binds cyclic GMP-AMP IEA Rattus norvegicus 71501 R-SSC-3244643 https://reactome.org/PathwayBrowser/#/R-SSC-3244643 STING binds cyclic GMP-AMP IEA Sus scrofa 71501 R-XTR-3244643 https://reactome.org/PathwayBrowser/#/R-XTR-3244643 STING binds cyclic GMP-AMP IEA Xenopus tropicalis 71553 R-BTA-6799581 https://reactome.org/PathwayBrowser/#/R-BTA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Bos taurus 71553 R-BTA-8853710 https://reactome.org/PathwayBrowser/#/R-BTA-8853710 MANBA hydrolyses GlcNAc:Man IEA Bos taurus 71553 R-CEL-6799581 https://reactome.org/PathwayBrowser/#/R-CEL-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Caenorhabditis elegans 71553 R-CEL-8853710 https://reactome.org/PathwayBrowser/#/R-CEL-8853710 MANBA hydrolyses GlcNAc:Man IEA Caenorhabditis elegans 71553 R-CFA-8853710 https://reactome.org/PathwayBrowser/#/R-CFA-8853710 MANBA hydrolyses GlcNAc:Man IEA Canis familiaris 71553 R-DDI-6799581 https://reactome.org/PathwayBrowser/#/R-DDI-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Dictyostelium discoideum 71553 R-DDI-8853710 https://reactome.org/PathwayBrowser/#/R-DDI-8853710 MANBA hydrolyses GlcNAc:Man IEA Dictyostelium discoideum 71553 R-DME-6799581 https://reactome.org/PathwayBrowser/#/R-DME-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Drosophila melanogaster 71553 R-DME-8853710 https://reactome.org/PathwayBrowser/#/R-DME-8853710 MANBA hydrolyses GlcNAc:Man IEA Drosophila melanogaster 71553 R-DRE-8853710 https://reactome.org/PathwayBrowser/#/R-DRE-8853710 MANBA hydrolyses GlcNAc:Man IEA Danio rerio 71553 R-GGA-6799581 https://reactome.org/PathwayBrowser/#/R-GGA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Gallus gallus 71553 R-GGA-8853710 https://reactome.org/PathwayBrowser/#/R-GGA-8853710 MANBA hydrolyses GlcNAc:Man IEA Gallus gallus 71553 R-HSA-6799581 https://reactome.org/PathwayBrowser/#/R-HSA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man TAS Homo sapiens 71553 R-HSA-8853710 https://reactome.org/PathwayBrowser/#/R-HSA-8853710 MANBA hydrolyses GlcNAc:Man TAS Homo sapiens 71553 R-MMU-6799581 https://reactome.org/PathwayBrowser/#/R-MMU-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Mus musculus 71553 R-MMU-8853710 https://reactome.org/PathwayBrowser/#/R-MMU-8853710 MANBA hydrolyses GlcNAc:Man IEA Mus musculus 71553 R-RNO-6799581 https://reactome.org/PathwayBrowser/#/R-RNO-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Rattus norvegicus 71553 R-RNO-8853710 https://reactome.org/PathwayBrowser/#/R-RNO-8853710 MANBA hydrolyses GlcNAc:Man IEA Rattus norvegicus 71553 R-SSC-6799581 https://reactome.org/PathwayBrowser/#/R-SSC-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Sus scrofa 71553 R-SSC-8853710 https://reactome.org/PathwayBrowser/#/R-SSC-8853710 MANBA hydrolyses GlcNAc:Man IEA Sus scrofa 71553 R-XTR-6799581 https://reactome.org/PathwayBrowser/#/R-XTR-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Xenopus tropicalis 71553 R-XTR-8853710 https://reactome.org/PathwayBrowser/#/R-XTR-8853710 MANBA hydrolyses GlcNAc:Man IEA Xenopus tropicalis 71952 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 71953 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 71954 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 71955 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 71956 R-HSA-1218824 https://reactome.org/PathwayBrowser/#/R-HSA-1218824 HSP90 is inactivated by binding to benzaquinoid ansamycins TAS Homo sapiens 71957 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 71958 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 71980 R-HSA-2466831 https://reactome.org/PathwayBrowser/#/R-HSA-2466831 A2PE hydrolyses to A2E TAS Homo sapiens 71980 R-HSA-2467738 https://reactome.org/PathwayBrowser/#/R-HSA-2467738 A2E translocates to RPE cells TAS Homo sapiens 71980 R-HSA-2467761 https://reactome.org/PathwayBrowser/#/R-HSA-2467761 A2E is phagocytosed TAS Homo sapiens 7207 R-BTA-174967 https://reactome.org/PathwayBrowser/#/R-BTA-174967 NAT2 acetylation IEA Bos taurus 7207 R-DRE-174967 https://reactome.org/PathwayBrowser/#/R-DRE-174967 NAT2 acetylation IEA Danio rerio 7207 R-GGA-174967 https://reactome.org/PathwayBrowser/#/R-GGA-174967 NAT2 acetylation IEA Gallus gallus 7207 R-HSA-174967 https://reactome.org/PathwayBrowser/#/R-HSA-174967 NAT2 acetylation TAS Homo sapiens 7207 R-MMU-174967 https://reactome.org/PathwayBrowser/#/R-MMU-174967 NAT2 acetylation IEA Mus musculus 7207 R-RNO-174967 https://reactome.org/PathwayBrowser/#/R-RNO-174967 NAT2 acetylation IEA Rattus norvegicus 7207 R-SSC-174967 https://reactome.org/PathwayBrowser/#/R-SSC-174967 NAT2 acetylation IEA Sus scrofa 72296 R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 72296 R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 72296 R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 72296 R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 72296 R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 72296 R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 72296 R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 72296 R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 72296 R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 72296 R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 72296 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 72296 R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 72296 R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 72296 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 72296 R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 72296 R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 72296 R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 72296 R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 72296 R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 72296 R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 72296 R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 72296 R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 72296 R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 72296 R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 72296 R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 72296 R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 72296 R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 72296 R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 72296 R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 72296 R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 72587 R-BTA-209891 https://reactome.org/PathwayBrowser/#/R-BTA-209891 Dopamine is oxidised to noradrenaline IEA Bos taurus 72587 R-BTA-209903 https://reactome.org/PathwayBrowser/#/R-BTA-209903 Noradrenaline is converted to adrenaline IEA Bos taurus 72587 R-BTA-374896 https://reactome.org/PathwayBrowser/#/R-BTA-374896 Uptake of Noradrenaline IEA Bos taurus 72587 R-BTA-374899 https://reactome.org/PathwayBrowser/#/R-BTA-374899 Release of noradrenaline at the synapse IEA Bos taurus 72587 R-BTA-374909 https://reactome.org/PathwayBrowser/#/R-BTA-374909 Catabolism of Noradrenaline IEA Bos taurus 72587 R-BTA-374919 https://reactome.org/PathwayBrowser/#/R-BTA-374919 Noradrenaline clearance from the synaptic cleft IEA Bos taurus 72587 R-BTA-374922 https://reactome.org/PathwayBrowser/#/R-BTA-374922 Noradrenalin synaptic vesicle docking and priming IEA Bos taurus 72587 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 72587 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 72587 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 72587 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 72587 R-BTA-390663 https://reactome.org/PathwayBrowser/#/R-BTA-390663 ADRA2A,B,C bind ADR,NAd IEA Bos taurus 72587 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 72587 R-BTA-400071 https://reactome.org/PathwayBrowser/#/R-BTA-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Bos taurus 72587 R-BTA-400092 https://reactome.org/PathwayBrowser/#/R-BTA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Bos taurus 72587 R-BTA-443997 https://reactome.org/PathwayBrowser/#/R-BTA-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Bos taurus 72587 R-BTA-444160 https://reactome.org/PathwayBrowser/#/R-BTA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Bos taurus 72587 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 72587 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 72587 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 72587 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 72587 R-BTA-5684862 https://reactome.org/PathwayBrowser/#/R-BTA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Bos taurus 72587 R-BTA-727740 https://reactome.org/PathwayBrowser/#/R-BTA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 72587 R-BTA-727768 https://reactome.org/PathwayBrowser/#/R-BTA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 72587 R-BTA-749446 https://reactome.org/PathwayBrowser/#/R-BTA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Bos taurus 72587 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 72587 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 72587 R-BTA-749453 https://reactome.org/PathwayBrowser/#/R-BTA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Bos taurus 72587 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 72587 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 72587 R-BTA-751019 https://reactome.org/PathwayBrowser/#/R-BTA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Bos taurus 72587 R-BTA-751024 https://reactome.org/PathwayBrowser/#/R-BTA-751024 The Ligand:GPCR:Gz complex dissociates IEA Bos taurus 72587 R-BTA-751027 https://reactome.org/PathwayBrowser/#/R-BTA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Bos taurus 72587 R-BTA-751029 https://reactome.org/PathwayBrowser/#/R-BTA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Bos taurus 72587 R-BTA-8851797 https://reactome.org/PathwayBrowser/#/R-BTA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Bos taurus 72587 R-BTA-8852167 https://reactome.org/PathwayBrowser/#/R-BTA-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Bos taurus 72587 R-BTA-8866269 https://reactome.org/PathwayBrowser/#/R-BTA-8866269 ARRB bind GPCRs IEA Bos taurus 72587 R-BTA-8866283 https://reactome.org/PathwayBrowser/#/R-BTA-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Bos taurus 72587 R-BTA-8867754 https://reactome.org/PathwayBrowser/#/R-BTA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Bos taurus 72587 R-BTA-8867756 https://reactome.org/PathwayBrowser/#/R-BTA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Bos taurus 72587 R-BTA-8868071 https://reactome.org/PathwayBrowser/#/R-BTA-8868071 Clathrin recruits PIK3C2A IEA Bos taurus 72587 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 72587 R-BTA-8868230 https://reactome.org/PathwayBrowser/#/R-BTA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Bos taurus 72587 R-BTA-8868236 https://reactome.org/PathwayBrowser/#/R-BTA-8868236 BAR domain proteins recruit dynamin IEA Bos taurus 72587 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 72587 R-BTA-8868651 https://reactome.org/PathwayBrowser/#/R-BTA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Bos taurus 72587 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 72587 R-BTA-8868659 https://reactome.org/PathwayBrowser/#/R-BTA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Bos taurus 72587 R-BTA-8868660 https://reactome.org/PathwayBrowser/#/R-BTA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Bos taurus 72587 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 72587 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 72587 R-BTA-8871194 https://reactome.org/PathwayBrowser/#/R-BTA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Bos taurus 72587 R-BTA-8982641 https://reactome.org/PathwayBrowser/#/R-BTA-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Bos taurus 72587 R-BTA-8982645 https://reactome.org/PathwayBrowser/#/R-BTA-8982645 GRKs bind ADRB2:Catecholamine IEA Bos taurus 72587 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 72587 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 72587 R-CEL-209903 https://reactome.org/PathwayBrowser/#/R-CEL-209903 Noradrenaline is converted to adrenaline IEA Caenorhabditis elegans 72587 R-CEL-374896 https://reactome.org/PathwayBrowser/#/R-CEL-374896 Uptake of Noradrenaline IEA Caenorhabditis elegans 72587 R-CEL-374899 https://reactome.org/PathwayBrowser/#/R-CEL-374899 Release of noradrenaline at the synapse IEA Caenorhabditis elegans 72587 R-CEL-374919 https://reactome.org/PathwayBrowser/#/R-CEL-374919 Noradrenaline clearance from the synaptic cleft IEA Caenorhabditis elegans 72587 R-CEL-374922 https://reactome.org/PathwayBrowser/#/R-CEL-374922 Noradrenalin synaptic vesicle docking and priming IEA Caenorhabditis elegans 72587 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 72587 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 72587 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 72587 R-CEL-390663 https://reactome.org/PathwayBrowser/#/R-CEL-390663 ADRA2A,B,C bind ADR,NAd IEA Caenorhabditis elegans 72587 R-CEL-400071 https://reactome.org/PathwayBrowser/#/R-CEL-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Caenorhabditis elegans 72587 R-CEL-400092 https://reactome.org/PathwayBrowser/#/R-CEL-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Caenorhabditis elegans 72587 R-CEL-443997 https://reactome.org/PathwayBrowser/#/R-CEL-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 72587 R-CEL-444160 https://reactome.org/PathwayBrowser/#/R-CEL-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Caenorhabditis elegans 72587 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 72587 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 72587 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 72587 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 72587 R-CEL-749446 https://reactome.org/PathwayBrowser/#/R-CEL-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Caenorhabditis elegans 72587 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 72587 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 72587 R-CEL-749453 https://reactome.org/PathwayBrowser/#/R-CEL-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Caenorhabditis elegans 72587 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 72587 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 72587 R-CEL-751019 https://reactome.org/PathwayBrowser/#/R-CEL-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Caenorhabditis elegans 72587 R-CEL-751024 https://reactome.org/PathwayBrowser/#/R-CEL-751024 The Ligand:GPCR:Gz complex dissociates IEA Caenorhabditis elegans 72587 R-CEL-751027 https://reactome.org/PathwayBrowser/#/R-CEL-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Caenorhabditis elegans 72587 R-CEL-751029 https://reactome.org/PathwayBrowser/#/R-CEL-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Caenorhabditis elegans 72587 R-CFA-209891 https://reactome.org/PathwayBrowser/#/R-CFA-209891 Dopamine is oxidised to noradrenaline IEA Canis familiaris 72587 R-CFA-209903 https://reactome.org/PathwayBrowser/#/R-CFA-209903 Noradrenaline is converted to adrenaline IEA Canis familiaris 72587 R-CFA-374896 https://reactome.org/PathwayBrowser/#/R-CFA-374896 Uptake of Noradrenaline IEA Canis familiaris 72587 R-CFA-374899 https://reactome.org/PathwayBrowser/#/R-CFA-374899 Release of noradrenaline at the synapse IEA Canis familiaris 72587 R-CFA-374909 https://reactome.org/PathwayBrowser/#/R-CFA-374909 Catabolism of Noradrenaline IEA Canis familiaris 72587 R-CFA-374919 https://reactome.org/PathwayBrowser/#/R-CFA-374919 Noradrenaline clearance from the synaptic cleft IEA Canis familiaris 72587 R-CFA-374922 https://reactome.org/PathwayBrowser/#/R-CFA-374922 Noradrenalin synaptic vesicle docking and priming IEA Canis familiaris 72587 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 72587 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 72587 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 72587 R-CFA-390663 https://reactome.org/PathwayBrowser/#/R-CFA-390663 ADRA2A,B,C bind ADR,NAd IEA Canis familiaris 72587 R-CFA-400071 https://reactome.org/PathwayBrowser/#/R-CFA-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Canis familiaris 72587 R-CFA-400092 https://reactome.org/PathwayBrowser/#/R-CFA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Canis familiaris 72587 R-CFA-443997 https://reactome.org/PathwayBrowser/#/R-CFA-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Canis familiaris 72587 R-CFA-444160 https://reactome.org/PathwayBrowser/#/R-CFA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Canis familiaris 72587 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 72587 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 72587 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 72587 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 72587 R-CFA-5684862 https://reactome.org/PathwayBrowser/#/R-CFA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Canis familiaris 72587 R-CFA-727740 https://reactome.org/PathwayBrowser/#/R-CFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 72587 R-CFA-727768 https://reactome.org/PathwayBrowser/#/R-CFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 72587 R-CFA-749446 https://reactome.org/PathwayBrowser/#/R-CFA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Canis familiaris 72587 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 72587 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 72587 R-CFA-749453 https://reactome.org/PathwayBrowser/#/R-CFA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Canis familiaris 72587 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 72587 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 72587 R-CFA-751019 https://reactome.org/PathwayBrowser/#/R-CFA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Canis familiaris 72587 R-CFA-751024 https://reactome.org/PathwayBrowser/#/R-CFA-751024 The Ligand:GPCR:Gz complex dissociates IEA Canis familiaris 72587 R-CFA-751027 https://reactome.org/PathwayBrowser/#/R-CFA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Canis familiaris 72587 R-CFA-751029 https://reactome.org/PathwayBrowser/#/R-CFA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Canis familiaris 72587 R-CFA-8851797 https://reactome.org/PathwayBrowser/#/R-CFA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Canis familiaris 72587 R-CFA-8852167 https://reactome.org/PathwayBrowser/#/R-CFA-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Canis familiaris 72587 R-CFA-8866269 https://reactome.org/PathwayBrowser/#/R-CFA-8866269 ARRB bind GPCRs IEA Canis familiaris 72587 R-CFA-8866283 https://reactome.org/PathwayBrowser/#/R-CFA-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Canis familiaris 72587 R-CFA-8867754 https://reactome.org/PathwayBrowser/#/R-CFA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Canis familiaris 72587 R-CFA-8867756 https://reactome.org/PathwayBrowser/#/R-CFA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Canis familiaris 72587 R-CFA-8868071 https://reactome.org/PathwayBrowser/#/R-CFA-8868071 Clathrin recruits PIK3C2A IEA Canis familiaris 72587 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 72587 R-CFA-8868230 https://reactome.org/PathwayBrowser/#/R-CFA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Canis familiaris 72587 R-CFA-8868236 https://reactome.org/PathwayBrowser/#/R-CFA-8868236 BAR domain proteins recruit dynamin IEA Canis familiaris 72587 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 72587 R-CFA-8868651 https://reactome.org/PathwayBrowser/#/R-CFA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Canis familiaris 72587 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 72587 R-CFA-8868659 https://reactome.org/PathwayBrowser/#/R-CFA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Canis familiaris 72587 R-CFA-8868660 https://reactome.org/PathwayBrowser/#/R-CFA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Canis familiaris 72587 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 72587 R-CFA-8871193 https://reactome.org/PathwayBrowser/#/R-CFA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Canis familiaris 72587 R-CFA-8871194 https://reactome.org/PathwayBrowser/#/R-CFA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Canis familiaris 72587 R-CFA-8982641 https://reactome.org/PathwayBrowser/#/R-CFA-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Canis familiaris 72587 R-CFA-8982645 https://reactome.org/PathwayBrowser/#/R-CFA-8982645 GRKs bind ADRB2:Catecholamine IEA Canis familiaris 72587 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 72587 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 72587 R-DDI-374909 https://reactome.org/PathwayBrowser/#/R-DDI-374909 Catabolism of Noradrenaline IEA Dictyostelium discoideum 72587 R-DDI-727740 https://reactome.org/PathwayBrowser/#/R-DDI-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 72587 R-DDI-727768 https://reactome.org/PathwayBrowser/#/R-DDI-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 72587 R-DME-209891 https://reactome.org/PathwayBrowser/#/R-DME-209891 Dopamine is oxidised to noradrenaline IEA Drosophila melanogaster 72587 R-DME-374896 https://reactome.org/PathwayBrowser/#/R-DME-374896 Uptake of Noradrenaline IEA Drosophila melanogaster 72587 R-DME-374899 https://reactome.org/PathwayBrowser/#/R-DME-374899 Release of noradrenaline at the synapse IEA Drosophila melanogaster 72587 R-DME-374919 https://reactome.org/PathwayBrowser/#/R-DME-374919 Noradrenaline clearance from the synaptic cleft IEA Drosophila melanogaster 72587 R-DME-374922 https://reactome.org/PathwayBrowser/#/R-DME-374922 Noradrenalin synaptic vesicle docking and priming IEA Drosophila melanogaster 72587 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 72587 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 72587 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 72587 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 72587 R-DME-390663 https://reactome.org/PathwayBrowser/#/R-DME-390663 ADRA2A,B,C bind ADR,NAd IEA Drosophila melanogaster 72587 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 72587 R-DME-400071 https://reactome.org/PathwayBrowser/#/R-DME-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Drosophila melanogaster 72587 R-DME-400092 https://reactome.org/PathwayBrowser/#/R-DME-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Drosophila melanogaster 72587 R-DME-443997 https://reactome.org/PathwayBrowser/#/R-DME-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 72587 R-DME-444160 https://reactome.org/PathwayBrowser/#/R-DME-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Drosophila melanogaster 72587 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 72587 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 72587 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 72587 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 72587 R-DME-727740 https://reactome.org/PathwayBrowser/#/R-DME-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 72587 R-DME-727768 https://reactome.org/PathwayBrowser/#/R-DME-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 72587 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 72587 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 72587 R-DME-749453 https://reactome.org/PathwayBrowser/#/R-DME-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Drosophila melanogaster 72587 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 72587 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 72587 R-DME-751019 https://reactome.org/PathwayBrowser/#/R-DME-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Drosophila melanogaster 72587 R-DME-751027 https://reactome.org/PathwayBrowser/#/R-DME-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Drosophila melanogaster 72587 R-DME-751029 https://reactome.org/PathwayBrowser/#/R-DME-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Drosophila melanogaster 72587 R-DME-8851797 https://reactome.org/PathwayBrowser/#/R-DME-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Drosophila melanogaster 72587 R-DME-8852167 https://reactome.org/PathwayBrowser/#/R-DME-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Drosophila melanogaster 72587 R-DME-8866269 https://reactome.org/PathwayBrowser/#/R-DME-8866269 ARRB bind GPCRs IEA Drosophila melanogaster 72587 R-DME-8866283 https://reactome.org/PathwayBrowser/#/R-DME-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Drosophila melanogaster 72587 R-DME-8867754 https://reactome.org/PathwayBrowser/#/R-DME-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Drosophila melanogaster 72587 R-DME-8867756 https://reactome.org/PathwayBrowser/#/R-DME-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Drosophila melanogaster 72587 R-DME-8868071 https://reactome.org/PathwayBrowser/#/R-DME-8868071 Clathrin recruits PIK3C2A IEA Drosophila melanogaster 72587 R-DME-8868072 https://reactome.org/PathwayBrowser/#/R-DME-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Drosophila melanogaster 72587 R-DME-8868236 https://reactome.org/PathwayBrowser/#/R-DME-8868236 BAR domain proteins recruit dynamin IEA Drosophila melanogaster 72587 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster 72587 R-DME-8868651 https://reactome.org/PathwayBrowser/#/R-DME-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Drosophila melanogaster 72587 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster 72587 R-DME-8868660 https://reactome.org/PathwayBrowser/#/R-DME-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Drosophila melanogaster 72587 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster 72587 R-DME-8871194 https://reactome.org/PathwayBrowser/#/R-DME-8871194 RAB5 and GAPVD1 bind AP-2 IEA Drosophila melanogaster 72587 R-DME-8982641 https://reactome.org/PathwayBrowser/#/R-DME-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Drosophila melanogaster 72587 R-DME-8982645 https://reactome.org/PathwayBrowser/#/R-DME-8982645 GRKs bind ADRB2:Catecholamine IEA Drosophila melanogaster 72587 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 72587 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 72587 R-DRE-209891 https://reactome.org/PathwayBrowser/#/R-DRE-209891 Dopamine is oxidised to noradrenaline IEA Danio rerio 72587 R-DRE-374896 https://reactome.org/PathwayBrowser/#/R-DRE-374896 Uptake of Noradrenaline IEA Danio rerio 72587 R-DRE-374919 https://reactome.org/PathwayBrowser/#/R-DRE-374919 Noradrenaline clearance from the synaptic cleft IEA Danio rerio 72587 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 72587 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 72587 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 72587 R-DRE-390663 https://reactome.org/PathwayBrowser/#/R-DRE-390663 ADRA2A,B,C bind ADR,NAd IEA Danio rerio 72587 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 72587 R-DRE-400071 https://reactome.org/PathwayBrowser/#/R-DRE-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Danio rerio 72587 R-DRE-400092 https://reactome.org/PathwayBrowser/#/R-DRE-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Danio rerio 72587 R-DRE-443997 https://reactome.org/PathwayBrowser/#/R-DRE-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Danio rerio 72587 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 72587 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 72587 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 72587 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 72587 R-DRE-727740 https://reactome.org/PathwayBrowser/#/R-DRE-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 72587 R-DRE-727768 https://reactome.org/PathwayBrowser/#/R-DRE-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 72587 R-DRE-751029 https://reactome.org/PathwayBrowser/#/R-DRE-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Danio rerio 72587 R-DRE-8852167 https://reactome.org/PathwayBrowser/#/R-DRE-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Danio rerio 72587 R-DRE-8866269 https://reactome.org/PathwayBrowser/#/R-DRE-8866269 ARRB bind GPCRs IEA Danio rerio 72587 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 72587 R-GGA-209891 https://reactome.org/PathwayBrowser/#/R-GGA-209891 Dopamine is oxidised to noradrenaline IEA Gallus gallus 72587 R-GGA-209903 https://reactome.org/PathwayBrowser/#/R-GGA-209903 Noradrenaline is converted to adrenaline IEA Gallus gallus 72587 R-GGA-374896 https://reactome.org/PathwayBrowser/#/R-GGA-374896 Uptake of Noradrenaline IEA Gallus gallus 72587 R-GGA-374909 https://reactome.org/PathwayBrowser/#/R-GGA-374909 Catabolism of Noradrenaline IEA Gallus gallus 72587 R-GGA-374919 https://reactome.org/PathwayBrowser/#/R-GGA-374919 Noradrenaline clearance from the synaptic cleft IEA Gallus gallus 72587 R-GGA-374922 https://reactome.org/PathwayBrowser/#/R-GGA-374922 Noradrenalin synaptic vesicle docking and priming IEA Gallus gallus 72587 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 72587 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 72587 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 72587 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 72587 R-GGA-390663 https://reactome.org/PathwayBrowser/#/R-GGA-390663 ADRA2A,B,C bind ADR,NAd IEA Gallus gallus 72587 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 72587 R-GGA-400071 https://reactome.org/PathwayBrowser/#/R-GGA-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Gallus gallus 72587 R-GGA-443997 https://reactome.org/PathwayBrowser/#/R-GGA-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Gallus gallus 72587 R-GGA-444160 https://reactome.org/PathwayBrowser/#/R-GGA-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Gallus gallus 72587 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 72587 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 72587 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 72587 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 72587 R-GGA-5684862 https://reactome.org/PathwayBrowser/#/R-GGA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Gallus gallus 72587 R-GGA-727740 https://reactome.org/PathwayBrowser/#/R-GGA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 72587 R-GGA-727768 https://reactome.org/PathwayBrowser/#/R-GGA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 72587 R-GGA-749446 https://reactome.org/PathwayBrowser/#/R-GGA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Gallus gallus 72587 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 72587 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 72587 R-GGA-749453 https://reactome.org/PathwayBrowser/#/R-GGA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Gallus gallus 72587 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 72587 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 72587 R-GGA-751019 https://reactome.org/PathwayBrowser/#/R-GGA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Gallus gallus 72587 R-GGA-751024 https://reactome.org/PathwayBrowser/#/R-GGA-751024 The Ligand:GPCR:Gz complex dissociates IEA Gallus gallus 72587 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus 72587 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus 72587 R-GGA-8851797 https://reactome.org/PathwayBrowser/#/R-GGA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Gallus gallus 72587 R-GGA-8982641 https://reactome.org/PathwayBrowser/#/R-GGA-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Gallus gallus 72587 R-GGA-8982645 https://reactome.org/PathwayBrowser/#/R-GGA-8982645 GRKs bind ADRB2:Catecholamine IEA Gallus gallus 72587 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 72587 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 72587 R-HSA-209891 https://reactome.org/PathwayBrowser/#/R-HSA-209891 Dopamine is oxidised to noradrenaline TAS Homo sapiens 72587 R-HSA-209903 https://reactome.org/PathwayBrowser/#/R-HSA-209903 Noradrenaline is converted to adrenaline TAS Homo sapiens 72587 R-HSA-351604 https://reactome.org/PathwayBrowser/#/R-HSA-351604 Noradrenaline translocates to the cytosol TAS Homo sapiens 72587 R-HSA-374896 https://reactome.org/PathwayBrowser/#/R-HSA-374896 Uptake of Noradrenaline TAS Homo sapiens 72587 R-HSA-374899 https://reactome.org/PathwayBrowser/#/R-HSA-374899 Release of noradrenaline at the synapse TAS Homo sapiens 72587 R-HSA-374909 https://reactome.org/PathwayBrowser/#/R-HSA-374909 Catabolism of Noradrenaline TAS Homo sapiens 72587 R-HSA-374919 https://reactome.org/PathwayBrowser/#/R-HSA-374919 Noradrenaline clearance from the synaptic cleft TAS Homo sapiens 72587 R-HSA-374922 https://reactome.org/PathwayBrowser/#/R-HSA-374922 Noradrenalin synaptic vesicle docking and priming TAS Homo sapiens 72587 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 72587 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 72587 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 72587 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 72587 R-HSA-390663 https://reactome.org/PathwayBrowser/#/R-HSA-390663 ADRA2A,B,C bind ADR,NAd TAS Homo sapiens 72587 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 72587 R-HSA-400071 https://reactome.org/PathwayBrowser/#/R-HSA-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline TAS Homo sapiens 72587 R-HSA-400092 https://reactome.org/PathwayBrowser/#/R-HSA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins TAS Homo sapiens 72587 R-HSA-443997 https://reactome.org/PathwayBrowser/#/R-HSA-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol TAS Homo sapiens 72587 R-HSA-444160 https://reactome.org/PathwayBrowser/#/R-HSA-444160 VMAT1/2 can mediate the transport of biogenic amines TAS Homo sapiens 72587 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 72587 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 72587 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 72587 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 72587 R-HSA-5659764 https://reactome.org/PathwayBrowser/#/R-HSA-5659764 Defective SLC6A2 does not cotransport NAd, Na+ from extracellular region to cytosol TAS Homo sapiens 72587 R-HSA-5684862 https://reactome.org/PathwayBrowser/#/R-HSA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. TAS Homo sapiens 72587 R-HSA-727740 https://reactome.org/PathwayBrowser/#/R-HSA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 72587 R-HSA-727768 https://reactome.org/PathwayBrowser/#/R-HSA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 72587 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 72587 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 72587 R-HSA-749446 https://reactome.org/PathwayBrowser/#/R-HSA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz TAS Homo sapiens 72587 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 72587 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 72587 R-HSA-749453 https://reactome.org/PathwayBrowser/#/R-HSA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz TAS Homo sapiens 72587 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 72587 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 72587 R-HSA-751019 https://reactome.org/PathwayBrowser/#/R-HSA-751019 The Ligand:GPCR:G12/13 complex dissociates TAS Homo sapiens 72587 R-HSA-751024 https://reactome.org/PathwayBrowser/#/R-HSA-751024 The Ligand:GPCR:Gz complex dissociates TAS Homo sapiens 72587 R-HSA-751027 https://reactome.org/PathwayBrowser/#/R-HSA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 TAS Homo sapiens 72587 R-HSA-751029 https://reactome.org/PathwayBrowser/#/R-HSA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 TAS Homo sapiens 72587 R-HSA-8851797 https://reactome.org/PathwayBrowser/#/R-HSA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated TAS Homo sapiens 72587 R-HSA-8852167 https://reactome.org/PathwayBrowser/#/R-HSA-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 TAS Homo sapiens 72587 R-HSA-8866269 https://reactome.org/PathwayBrowser/#/R-HSA-8866269 ARRB bind GPCRs TAS Homo sapiens 72587 R-HSA-8866283 https://reactome.org/PathwayBrowser/#/R-HSA-8866283 ARBB recruits GPCRs into clathrin-coated pits TAS Homo sapiens 72587 R-HSA-8867754 https://reactome.org/PathwayBrowser/#/R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit TAS Homo sapiens 72587 R-HSA-8867756 https://reactome.org/PathwayBrowser/#/R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit TAS Homo sapiens 72587 R-HSA-8868071 https://reactome.org/PathwayBrowser/#/R-HSA-8868071 Clathrin recruits PIK3C2A TAS Homo sapiens 72587 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 72587 R-HSA-8868230 https://reactome.org/PathwayBrowser/#/R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery TAS Homo sapiens 72587 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 72587 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 72587 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 72587 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 72587 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 72587 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 72587 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 72587 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 72587 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 72587 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 72587 R-HSA-8982641 https://reactome.org/PathwayBrowser/#/R-HSA-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 TAS Homo sapiens 72587 R-HSA-8982645 https://reactome.org/PathwayBrowser/#/R-HSA-8982645 GRKs bind ADRB2:Catecholamine TAS Homo sapiens 72587 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 72587 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 72587 R-MMU-209891 https://reactome.org/PathwayBrowser/#/R-MMU-209891 Dopamine is oxidised to noradrenaline IEA Mus musculus 72587 R-MMU-209903 https://reactome.org/PathwayBrowser/#/R-MMU-209903 Noradrenaline is converted to adrenaline IEA Mus musculus 72587 R-MMU-374896 https://reactome.org/PathwayBrowser/#/R-MMU-374896 Uptake of Noradrenaline IEA Mus musculus 72587 R-MMU-374899 https://reactome.org/PathwayBrowser/#/R-MMU-374899 Release of noradrenaline at the synapse IEA Mus musculus 72587 R-MMU-374909 https://reactome.org/PathwayBrowser/#/R-MMU-374909 Catabolism of Noradrenaline IEA Mus musculus 72587 R-MMU-374919 https://reactome.org/PathwayBrowser/#/R-MMU-374919 Noradrenaline clearance from the synaptic cleft IEA Mus musculus 72587 R-MMU-374922 https://reactome.org/PathwayBrowser/#/R-MMU-374922 Noradrenalin synaptic vesicle docking and priming IEA Mus musculus 72587 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 72587 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 72587 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 72587 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 72587 R-MMU-390663 https://reactome.org/PathwayBrowser/#/R-MMU-390663 ADRA2A,B,C bind ADR,NAd IEA Mus musculus 72587 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 72587 R-MMU-400071 https://reactome.org/PathwayBrowser/#/R-MMU-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Mus musculus 72587 R-MMU-400092 https://reactome.org/PathwayBrowser/#/R-MMU-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Mus musculus 72587 R-MMU-443997 https://reactome.org/PathwayBrowser/#/R-MMU-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Mus musculus 72587 R-MMU-444160 https://reactome.org/PathwayBrowser/#/R-MMU-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Mus musculus 72587 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 72587 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 72587 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 72587 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 72587 R-MMU-5684862 https://reactome.org/PathwayBrowser/#/R-MMU-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Mus musculus 72587 R-MMU-727740 https://reactome.org/PathwayBrowser/#/R-MMU-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 72587 R-MMU-727768 https://reactome.org/PathwayBrowser/#/R-MMU-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 72587 R-MMU-749446 https://reactome.org/PathwayBrowser/#/R-MMU-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Mus musculus 72587 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 72587 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 72587 R-MMU-749453 https://reactome.org/PathwayBrowser/#/R-MMU-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Mus musculus 72587 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 72587 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 72587 R-MMU-751019 https://reactome.org/PathwayBrowser/#/R-MMU-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Mus musculus 72587 R-MMU-751024 https://reactome.org/PathwayBrowser/#/R-MMU-751024 The Ligand:GPCR:Gz complex dissociates IEA Mus musculus 72587 R-MMU-751027 https://reactome.org/PathwayBrowser/#/R-MMU-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Mus musculus 72587 R-MMU-751029 https://reactome.org/PathwayBrowser/#/R-MMU-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Mus musculus 72587 R-MMU-8851797 https://reactome.org/PathwayBrowser/#/R-MMU-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Mus musculus 72587 R-MMU-8852167 https://reactome.org/PathwayBrowser/#/R-MMU-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Mus musculus 72587 R-MMU-8866269 https://reactome.org/PathwayBrowser/#/R-MMU-8866269 ARRB bind GPCRs IEA Mus musculus 72587 R-MMU-8866283 https://reactome.org/PathwayBrowser/#/R-MMU-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Mus musculus 72587 R-MMU-8867754 https://reactome.org/PathwayBrowser/#/R-MMU-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Mus musculus 72587 R-MMU-8867756 https://reactome.org/PathwayBrowser/#/R-MMU-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Mus musculus 72587 R-MMU-8868071 https://reactome.org/PathwayBrowser/#/R-MMU-8868071 Clathrin recruits PIK3C2A IEA Mus musculus 72587 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 72587 R-MMU-8868236 https://reactome.org/PathwayBrowser/#/R-MMU-8868236 BAR domain proteins recruit dynamin IEA Mus musculus 72587 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 72587 R-MMU-8868651 https://reactome.org/PathwayBrowser/#/R-MMU-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Mus musculus 72587 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 72587 R-MMU-8868659 https://reactome.org/PathwayBrowser/#/R-MMU-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Mus musculus 72587 R-MMU-8868660 https://reactome.org/PathwayBrowser/#/R-MMU-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Mus musculus 72587 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 72587 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 72587 R-MMU-8871194 https://reactome.org/PathwayBrowser/#/R-MMU-8871194 RAB5 and GAPVD1 bind AP-2 IEA Mus musculus 72587 R-MMU-8982641 https://reactome.org/PathwayBrowser/#/R-MMU-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Mus musculus 72587 R-MMU-8982645 https://reactome.org/PathwayBrowser/#/R-MMU-8982645 GRKs bind ADRB2:Catecholamine IEA Mus musculus 72587 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 72587 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 72587 R-PFA-443997 https://reactome.org/PathwayBrowser/#/R-PFA-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Plasmodium falciparum 72587 R-PFA-727740 https://reactome.org/PathwayBrowser/#/R-PFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 72587 R-PFA-727768 https://reactome.org/PathwayBrowser/#/R-PFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 72587 R-RNO-209891 https://reactome.org/PathwayBrowser/#/R-RNO-209891 Dopamine is oxidised to noradrenaline IEA Rattus norvegicus 72587 R-RNO-209903 https://reactome.org/PathwayBrowser/#/R-RNO-209903 Noradrenaline is converted to adrenaline IEA Rattus norvegicus 72587 R-RNO-374896 https://reactome.org/PathwayBrowser/#/R-RNO-374896 Uptake of Noradrenaline IEA Rattus norvegicus 72587 R-RNO-374899 https://reactome.org/PathwayBrowser/#/R-RNO-374899 Release of noradrenaline at the synapse IEA Rattus norvegicus 72587 R-RNO-374909 https://reactome.org/PathwayBrowser/#/R-RNO-374909 Catabolism of Noradrenaline IEA Rattus norvegicus 72587 R-RNO-374919 https://reactome.org/PathwayBrowser/#/R-RNO-374919 Noradrenaline clearance from the synaptic cleft IEA Rattus norvegicus 72587 R-RNO-374922 https://reactome.org/PathwayBrowser/#/R-RNO-374922 Noradrenalin synaptic vesicle docking and priming IEA Rattus norvegicus 72587 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 72587 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 72587 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 72587 R-RNO-390663 https://reactome.org/PathwayBrowser/#/R-RNO-390663 ADRA2A,B,C bind ADR,NAd IEA Rattus norvegicus 72587 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 72587 R-RNO-400071 https://reactome.org/PathwayBrowser/#/R-RNO-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Rattus norvegicus 72587 R-RNO-400092 https://reactome.org/PathwayBrowser/#/R-RNO-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Rattus norvegicus 72587 R-RNO-443997 https://reactome.org/PathwayBrowser/#/R-RNO-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Rattus norvegicus 72587 R-RNO-444160 https://reactome.org/PathwayBrowser/#/R-RNO-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Rattus norvegicus 72587 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 72587 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 72587 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 72587 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 72587 R-RNO-5684862 https://reactome.org/PathwayBrowser/#/R-RNO-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Rattus norvegicus 72587 R-RNO-727740 https://reactome.org/PathwayBrowser/#/R-RNO-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 72587 R-RNO-727768 https://reactome.org/PathwayBrowser/#/R-RNO-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 72587 R-RNO-749453 https://reactome.org/PathwayBrowser/#/R-RNO-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Rattus norvegicus 72587 R-RNO-751029 https://reactome.org/PathwayBrowser/#/R-RNO-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Rattus norvegicus 72587 R-RNO-8851797 https://reactome.org/PathwayBrowser/#/R-RNO-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Rattus norvegicus 72587 R-RNO-8852167 https://reactome.org/PathwayBrowser/#/R-RNO-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Rattus norvegicus 72587 R-RNO-8866269 https://reactome.org/PathwayBrowser/#/R-RNO-8866269 ARRB bind GPCRs IEA Rattus norvegicus 72587 R-RNO-8866283 https://reactome.org/PathwayBrowser/#/R-RNO-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Rattus norvegicus 72587 R-RNO-8867754 https://reactome.org/PathwayBrowser/#/R-RNO-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Rattus norvegicus 72587 R-RNO-8867756 https://reactome.org/PathwayBrowser/#/R-RNO-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Rattus norvegicus 72587 R-RNO-8868071 https://reactome.org/PathwayBrowser/#/R-RNO-8868071 Clathrin recruits PIK3C2A IEA Rattus norvegicus 72587 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 72587 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus 72587 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 72587 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus 72587 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 72587 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus 72587 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus 72587 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 72587 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 72587 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus 72587 R-RNO-8982641 https://reactome.org/PathwayBrowser/#/R-RNO-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Rattus norvegicus 72587 R-RNO-8982645 https://reactome.org/PathwayBrowser/#/R-RNO-8982645 GRKs bind ADRB2:Catecholamine IEA Rattus norvegicus 72587 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 72587 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 72587 R-SPO-444160 https://reactome.org/PathwayBrowser/#/R-SPO-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Schizosaccharomyces pombe 72587 R-SSC-209891 https://reactome.org/PathwayBrowser/#/R-SSC-209891 Dopamine is oxidised to noradrenaline IEA Sus scrofa 72587 R-SSC-209903 https://reactome.org/PathwayBrowser/#/R-SSC-209903 Noradrenaline is converted to adrenaline IEA Sus scrofa 72587 R-SSC-374896 https://reactome.org/PathwayBrowser/#/R-SSC-374896 Uptake of Noradrenaline IEA Sus scrofa 72587 R-SSC-374899 https://reactome.org/PathwayBrowser/#/R-SSC-374899 Release of noradrenaline at the synapse IEA Sus scrofa 72587 R-SSC-374909 https://reactome.org/PathwayBrowser/#/R-SSC-374909 Catabolism of Noradrenaline IEA Sus scrofa 72587 R-SSC-374919 https://reactome.org/PathwayBrowser/#/R-SSC-374919 Noradrenaline clearance from the synaptic cleft IEA Sus scrofa 72587 R-SSC-374922 https://reactome.org/PathwayBrowser/#/R-SSC-374922 Noradrenalin synaptic vesicle docking and priming IEA Sus scrofa 72587 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 72587 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 72587 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 72587 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 72587 R-SSC-390663 https://reactome.org/PathwayBrowser/#/R-SSC-390663 ADRA2A,B,C bind ADR,NAd IEA Sus scrofa 72587 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 72587 R-SSC-400071 https://reactome.org/PathwayBrowser/#/R-SSC-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Sus scrofa 72587 R-SSC-400092 https://reactome.org/PathwayBrowser/#/R-SSC-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Sus scrofa 72587 R-SSC-443997 https://reactome.org/PathwayBrowser/#/R-SSC-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Sus scrofa 72587 R-SSC-444160 https://reactome.org/PathwayBrowser/#/R-SSC-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Sus scrofa 72587 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 72587 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 72587 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 72587 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 72587 R-SSC-5684862 https://reactome.org/PathwayBrowser/#/R-SSC-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. IEA Sus scrofa 72587 R-SSC-727740 https://reactome.org/PathwayBrowser/#/R-SSC-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 72587 R-SSC-727768 https://reactome.org/PathwayBrowser/#/R-SSC-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 72587 R-SSC-749446 https://reactome.org/PathwayBrowser/#/R-SSC-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Sus scrofa 72587 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 72587 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 72587 R-SSC-749453 https://reactome.org/PathwayBrowser/#/R-SSC-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Sus scrofa 72587 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 72587 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 72587 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa 72587 R-SSC-751024 https://reactome.org/PathwayBrowser/#/R-SSC-751024 The Ligand:GPCR:Gz complex dissociates IEA Sus scrofa 72587 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa 72587 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa 72587 R-SSC-8851797 https://reactome.org/PathwayBrowser/#/R-SSC-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Sus scrofa 72587 R-SSC-8852167 https://reactome.org/PathwayBrowser/#/R-SSC-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Sus scrofa 72587 R-SSC-8866269 https://reactome.org/PathwayBrowser/#/R-SSC-8866269 ARRB bind GPCRs IEA Sus scrofa 72587 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa 72587 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa 72587 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa 72587 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa 72587 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 72587 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa 72587 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa 72587 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 72587 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa 72587 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 72587 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa 72587 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa 72587 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 72587 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 72587 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa 72587 R-SSC-8982641 https://reactome.org/PathwayBrowser/#/R-SSC-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Sus scrofa 72587 R-SSC-8982645 https://reactome.org/PathwayBrowser/#/R-SSC-8982645 GRKs bind ADRB2:Catecholamine IEA Sus scrofa 72587 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 72587 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 72587 R-XTR-209891 https://reactome.org/PathwayBrowser/#/R-XTR-209891 Dopamine is oxidised to noradrenaline IEA Xenopus tropicalis 72587 R-XTR-374896 https://reactome.org/PathwayBrowser/#/R-XTR-374896 Uptake of Noradrenaline IEA Xenopus tropicalis 72587 R-XTR-374919 https://reactome.org/PathwayBrowser/#/R-XTR-374919 Noradrenaline clearance from the synaptic cleft IEA Xenopus tropicalis 72587 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 72587 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 72587 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 72587 R-XTR-390663 https://reactome.org/PathwayBrowser/#/R-XTR-390663 ADRA2A,B,C bind ADR,NAd IEA Xenopus tropicalis 72587 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 72587 R-XTR-400071 https://reactome.org/PathwayBrowser/#/R-XTR-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Xenopus tropicalis 72587 R-XTR-400092 https://reactome.org/PathwayBrowser/#/R-XTR-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Xenopus tropicalis 72587 R-XTR-443997 https://reactome.org/PathwayBrowser/#/R-XTR-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 72587 R-XTR-444160 https://reactome.org/PathwayBrowser/#/R-XTR-444160 VMAT1/2 can mediate the transport of biogenic amines IEA Xenopus tropicalis 72587 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 72587 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 72587 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 72587 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 72587 R-XTR-749446 https://reactome.org/PathwayBrowser/#/R-XTR-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Xenopus tropicalis 72587 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 72587 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 72587 R-XTR-749453 https://reactome.org/PathwayBrowser/#/R-XTR-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Xenopus tropicalis 72587 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 72587 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 72587 R-XTR-751019 https://reactome.org/PathwayBrowser/#/R-XTR-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Xenopus tropicalis 72587 R-XTR-751024 https://reactome.org/PathwayBrowser/#/R-XTR-751024 The Ligand:GPCR:Gz complex dissociates IEA Xenopus tropicalis 72587 R-XTR-751027 https://reactome.org/PathwayBrowser/#/R-XTR-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Xenopus tropicalis 72587 R-XTR-751029 https://reactome.org/PathwayBrowser/#/R-XTR-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Xenopus tropicalis 72587 R-XTR-8851797 https://reactome.org/PathwayBrowser/#/R-XTR-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Xenopus tropicalis 72587 R-XTR-8852167 https://reactome.org/PathwayBrowser/#/R-XTR-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Xenopus tropicalis 72587 R-XTR-8866269 https://reactome.org/PathwayBrowser/#/R-XTR-8866269 ARRB bind GPCRs IEA Xenopus tropicalis 72587 R-XTR-8982641 https://reactome.org/PathwayBrowser/#/R-XTR-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Xenopus tropicalis 72587 R-XTR-8982645 https://reactome.org/PathwayBrowser/#/R-XTR-8982645 GRKs bind ADRB2:Catecholamine IEA Xenopus tropicalis 72587 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 72623 R-BTA-9027624 https://reactome.org/PathwayBrowser/#/R-BTA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Bos taurus 72623 R-CFA-9027624 https://reactome.org/PathwayBrowser/#/R-CFA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Canis familiaris 72623 R-DDI-9027624 https://reactome.org/PathwayBrowser/#/R-DDI-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Dictyostelium discoideum 72623 R-DRE-9027624 https://reactome.org/PathwayBrowser/#/R-DRE-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Danio rerio 72623 R-GGA-9027624 https://reactome.org/PathwayBrowser/#/R-GGA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Gallus gallus 72623 R-HSA-9027624 https://reactome.org/PathwayBrowser/#/R-HSA-9027624 ALOX5 oxidises DHA to 7-HDHA TAS Homo sapiens 72623 R-HSA-9027631 https://reactome.org/PathwayBrowser/#/R-HSA-9027631 5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA TAS Homo sapiens 72623 R-MMU-9027624 https://reactome.org/PathwayBrowser/#/R-MMU-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Mus musculus 72623 R-RNO-9027624 https://reactome.org/PathwayBrowser/#/R-RNO-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Rattus norvegicus 72623 R-SSC-9027624 https://reactome.org/PathwayBrowser/#/R-SSC-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Sus scrofa 72623 R-XTR-9027624 https://reactome.org/PathwayBrowser/#/R-XTR-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Xenopus tropicalis 72637 R-BTA-9027627 https://reactome.org/PathwayBrowser/#/R-BTA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Bos taurus 72637 R-CFA-9027627 https://reactome.org/PathwayBrowser/#/R-CFA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Canis familiaris 72637 R-DRE-9027627 https://reactome.org/PathwayBrowser/#/R-DRE-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Danio rerio 72637 R-GGA-9027627 https://reactome.org/PathwayBrowser/#/R-GGA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Gallus gallus 72637 R-HSA-9027562 https://reactome.org/PathwayBrowser/#/R-HSA-9027562 Dehydrogenase dehydrogenates 17-HDHA to 17-oxo-DHA TAS Homo sapiens 72637 R-HSA-9027627 https://reactome.org/PathwayBrowser/#/R-HSA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) TAS Homo sapiens 72637 R-MMU-9027627 https://reactome.org/PathwayBrowser/#/R-MMU-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Mus musculus 72637 R-RNO-9027627 https://reactome.org/PathwayBrowser/#/R-RNO-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Rattus norvegicus 72637 R-SSC-9027627 https://reactome.org/PathwayBrowser/#/R-SSC-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Sus scrofa 72637 R-XTR-9027627 https://reactome.org/PathwayBrowser/#/R-XTR-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Xenopus tropicalis 72790 R-BTA-6786239 https://reactome.org/PathwayBrowser/#/R-BTA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Bos taurus 72790 R-CEL-6786239 https://reactome.org/PathwayBrowser/#/R-CEL-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Caenorhabditis elegans 72790 R-CFA-6786239 https://reactome.org/PathwayBrowser/#/R-CFA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Canis familiaris 72790 R-DME-6786239 https://reactome.org/PathwayBrowser/#/R-DME-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Drosophila melanogaster 72790 R-DRE-6786239 https://reactome.org/PathwayBrowser/#/R-DRE-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Danio rerio 72790 R-GGA-6786239 https://reactome.org/PathwayBrowser/#/R-GGA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Gallus gallus 72790 R-HSA-6786239 https://reactome.org/PathwayBrowser/#/R-HSA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE TAS Homo sapiens 72790 R-MMU-6786239 https://reactome.org/PathwayBrowser/#/R-MMU-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Mus musculus 72790 R-RNO-6786239 https://reactome.org/PathwayBrowser/#/R-RNO-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Rattus norvegicus 72790 R-SSC-6786239 https://reactome.org/PathwayBrowser/#/R-SSC-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Sus scrofa 72790 R-XTR-6786239 https://reactome.org/PathwayBrowser/#/R-XTR-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Xenopus tropicalis 72801 R-BTA-9027628 https://reactome.org/PathwayBrowser/#/R-BTA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Bos taurus 72801 R-CFA-9027628 https://reactome.org/PathwayBrowser/#/R-CFA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Canis familiaris 72801 R-DDI-9027628 https://reactome.org/PathwayBrowser/#/R-DDI-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Dictyostelium discoideum 72801 R-DRE-9027628 https://reactome.org/PathwayBrowser/#/R-DRE-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Danio rerio 72801 R-GGA-9027628 https://reactome.org/PathwayBrowser/#/R-GGA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Gallus gallus 72801 R-HSA-9027628 https://reactome.org/PathwayBrowser/#/R-HSA-9027628 ALOX5 oxidises EPA to 5-HEPE TAS Homo sapiens 72801 R-HSA-9027632 https://reactome.org/PathwayBrowser/#/R-HSA-9027632 5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA TAS Homo sapiens 72801 R-MMU-9027628 https://reactome.org/PathwayBrowser/#/R-MMU-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Mus musculus 72801 R-RNO-9027628 https://reactome.org/PathwayBrowser/#/R-RNO-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Rattus norvegicus 72801 R-SSC-9027628 https://reactome.org/PathwayBrowser/#/R-SSC-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Sus scrofa 72801 R-XTR-9027628 https://reactome.org/PathwayBrowser/#/R-XTR-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Xenopus tropicalis 73044 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 73044 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 73044 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 73044 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 73044 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 73044 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 73044 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 73044 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 73044 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 73044 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 73044 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 73044 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 73044 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 73044 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 73044 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 73044 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 73044 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 73044 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 73110 R-BTA-8850326 https://reactome.org/PathwayBrowser/#/R-BTA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Bos taurus 73110 R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 73110 R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 73110 R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 73110 R-GGA-8850326 https://reactome.org/PathwayBrowser/#/R-GGA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Gallus gallus 73110 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 73110 R-HSA-8850326 https://reactome.org/PathwayBrowser/#/R-HSA-8850326 TCR binds self-lipid-based antigen via CD1 TAS Homo sapiens 73110 R-HSA-9840579 https://reactome.org/PathwayBrowser/#/R-HSA-9840579 GM1 localizes to ILV membrane TAS Homo sapiens 73110 R-HSA-9840581 https://reactome.org/PathwayBrowser/#/R-HSA-9840581 GM1 localizes to endosome membrane TAS Homo sapiens 73110 R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 73110 R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 73110 R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 73110 R-SSC-8850326 https://reactome.org/PathwayBrowser/#/R-SSC-8850326 TCR binds self-lipid-based antigen via CD1 IEA Sus scrofa 73110 R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 73222 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 73222 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 73222 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 73222 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 73222 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 73222 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 73222 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 73222 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 73222 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 73222 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 73222 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 73222 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 73222 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 73222 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 73222 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 73222 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 73222 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 73222 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 73222 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 73222 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 73222 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 73222 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 73222 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 73222 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 73222 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 73222 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 73222 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 73222 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 73222 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 73222 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 73222 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 73222 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 73222 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 73222 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 73222 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 73222 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 73222 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 73222 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 73222 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 73222 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 73222 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 73222 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 73224 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 73224 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 73224 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 73224 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 73224 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 73224 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 73224 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 73224 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 73224 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 73224 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 73224 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 73224 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 73224 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 73224 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 73224 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 73224 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 73224 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 73224 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 73224 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 73224 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 73224 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 73224 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 73224 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 73224 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 73224 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 73224 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 73224 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 73224 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 73224 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 73224 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 73224 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 73224 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 73224 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 73224 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 73224 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 73224 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 73224 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 73224 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 73224 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 73224 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 73224 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 73224 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 73226 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 73226 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 73226 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 73226 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 73226 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 73226 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 73226 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 73226 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 73226 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 73226 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 73226 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 73226 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 73226 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 73226 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 73226 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 73226 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 73226 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 73226 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 73226 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 73226 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 73226 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 73226 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 73226 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 73226 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 73226 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 73226 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 73226 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 73226 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 73226 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 73226 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 73226 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 73226 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 73226 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 73226 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 73226 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 73226 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 73226 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 73226 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 73226 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 73226 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 73226 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 73226 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 73228 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 73228 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 73228 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 73228 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 73228 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 73228 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 73228 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 73228 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 73228 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 73228 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 73228 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 73228 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 73228 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 73228 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 73228 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 73228 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 73228 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 73228 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 73228 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 73228 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 73228 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 73228 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 73228 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 73228 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 73228 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 73228 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 73228 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 73228 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 73228 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 73228 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 73228 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 73228 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 73228 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 73228 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 73228 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 73228 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 73228 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 73228 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 73228 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 73228 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 73228 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 73228 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 73231 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 73231 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 73231 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 73231 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 73231 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 73231 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 73231 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 73231 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 73231 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 73231 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 73231 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 73231 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 73231 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 73231 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 73231 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 73231 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 73231 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 73231 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 73231 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 73231 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 73231 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 73231 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 73231 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 73231 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 73231 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 73231 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 73231 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 73231 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 73231 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 73231 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 73231 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 73231 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 73231 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 73231 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 73231 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 73231 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 73231 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 73231 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 73231 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 73231 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 73231 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 73231 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 73232 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 73232 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 73232 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 73232 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 73232 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 73232 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 73232 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 73232 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 73232 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 73232 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 73232 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 73232 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 73232 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 73232 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 73232 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 73232 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 73232 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 73232 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 73232 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 73232 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 73232 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 73232 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 73232 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 73232 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 73232 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 73232 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 73232 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 73232 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 73232 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 73232 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 73232 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 73232 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 73232 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 73232 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 73232 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 73232 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 73232 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 73232 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 73232 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 73232 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 73232 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 73232 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 73235 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 73235 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 73235 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 73235 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 73235 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 73235 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 73235 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 73235 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 73235 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 73235 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 73235 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 73235 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 73235 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 73235 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 73235 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 73235 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 73235 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 73235 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 73235 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 73235 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 73235 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 73235 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 73235 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 73235 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 73235 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 73235 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 73235 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 73235 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 73235 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 73235 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 73235 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 73235 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 73235 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 73235 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 73235 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 73235 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 73235 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 73235 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 73235 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 73235 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 73235 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 73235 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 73236 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 73236 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 73236 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 73236 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 73236 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 73236 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 73236 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 73236 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 73236 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 73236 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 73236 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 73236 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 73236 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 73236 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 73236 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 73236 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 73236 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 73236 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 73236 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 73236 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 73236 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 73236 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 73236 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 73236 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 73236 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 73236 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 73236 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 73236 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 73236 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 73236 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 73236 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 73236 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 73236 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 73236 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 73236 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 73236 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 73236 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 73236 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 73236 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 73236 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 73236 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 73236 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 73237 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 73237 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 73237 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 73237 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 73237 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 73237 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 73237 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 73237 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 73237 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 73237 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 73237 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 73237 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 73237 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 73237 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 73237 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 73237 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 73237 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 73237 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 73237 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 73237 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 73237 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 73237 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 73237 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 73237 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 73237 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 73237 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 73237 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 73237 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 73237 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 73237 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 73237 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 73237 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 73237 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 73237 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 73237 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 73237 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 73237 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 73237 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 73237 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 73237 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 73237 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 73237 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 73239 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 73239 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 73239 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 73239 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 73239 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 73239 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 73239 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 73239 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 73239 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 73239 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 73239 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 73239 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 73239 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 73239 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 73239 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 73239 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 73239 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 73239 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 73239 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 73239 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 73239 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 73239 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 73239 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 73239 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 73239 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 73239 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 73239 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 73239 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 73239 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 73239 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 73239 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 73239 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 73239 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 73239 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 73239 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 73239 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 73239 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 73239 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 73239 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 73239 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 73239 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 73239 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 73315 R-BTA-1483002 https://reactome.org/PathwayBrowser/#/R-BTA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Bos taurus 73315 R-BTA-390427 https://reactome.org/PathwayBrowser/#/R-BTA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Bos taurus 73315 R-BTA-75883 https://reactome.org/PathwayBrowser/#/R-BTA-75883 DHRS7B reduces GO3P to HXDG3P IEA Bos taurus 73315 R-CEL-1483002 https://reactome.org/PathwayBrowser/#/R-CEL-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Caenorhabditis elegans 73315 R-CEL-390427 https://reactome.org/PathwayBrowser/#/R-CEL-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Caenorhabditis elegans 73315 R-CEL-75883 https://reactome.org/PathwayBrowser/#/R-CEL-75883 DHRS7B reduces GO3P to HXDG3P IEA Caenorhabditis elegans 73315 R-CFA-1483002 https://reactome.org/PathwayBrowser/#/R-CFA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Canis familiaris 73315 R-CFA-390427 https://reactome.org/PathwayBrowser/#/R-CFA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Canis familiaris 73315 R-CFA-75883 https://reactome.org/PathwayBrowser/#/R-CFA-75883 DHRS7B reduces GO3P to HXDG3P IEA Canis familiaris 73315 R-DME-1483002 https://reactome.org/PathwayBrowser/#/R-DME-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Drosophila melanogaster 73315 R-DME-390427 https://reactome.org/PathwayBrowser/#/R-DME-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Drosophila melanogaster 73315 R-DME-75883 https://reactome.org/PathwayBrowser/#/R-DME-75883 DHRS7B reduces GO3P to HXDG3P IEA Drosophila melanogaster 73315 R-DRE-75883 https://reactome.org/PathwayBrowser/#/R-DRE-75883 DHRS7B reduces GO3P to HXDG3P IEA Danio rerio 73315 R-GGA-75883 https://reactome.org/PathwayBrowser/#/R-GGA-75883 DHRS7B reduces GO3P to HXDG3P IEA Gallus gallus 73315 R-HSA-1483002 https://reactome.org/PathwayBrowser/#/R-HSA-1483002 DHAP is converted to 1-acyl GO3P by GNPAT TAS Homo sapiens 73315 R-HSA-390402 https://reactome.org/PathwayBrowser/#/R-HSA-390402 Movement of O-hexadecylglycerone phosphate from the peroxisomal matrix to the cytosol TAS Homo sapiens 73315 R-HSA-390427 https://reactome.org/PathwayBrowser/#/R-HSA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate TAS Homo sapiens 73315 R-HSA-75883 https://reactome.org/PathwayBrowser/#/R-HSA-75883 DHRS7B reduces GO3P to HXDG3P TAS Homo sapiens 73315 R-MMU-1483002 https://reactome.org/PathwayBrowser/#/R-MMU-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Mus musculus 73315 R-MMU-390427 https://reactome.org/PathwayBrowser/#/R-MMU-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Mus musculus 73315 R-MMU-75883 https://reactome.org/PathwayBrowser/#/R-MMU-75883 DHRS7B reduces GO3P to HXDG3P IEA Mus musculus 73315 R-RNO-1483002 https://reactome.org/PathwayBrowser/#/R-RNO-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Rattus norvegicus 73315 R-RNO-390427 https://reactome.org/PathwayBrowser/#/R-RNO-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Rattus norvegicus 73315 R-RNO-75883 https://reactome.org/PathwayBrowser/#/R-RNO-75883 DHRS7B reduces GO3P to HXDG3P IEA Rattus norvegicus 73315 R-SSC-1483002 https://reactome.org/PathwayBrowser/#/R-SSC-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Sus scrofa 73315 R-SSC-390427 https://reactome.org/PathwayBrowser/#/R-SSC-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Sus scrofa 73315 R-SSC-75883 https://reactome.org/PathwayBrowser/#/R-SSC-75883 DHRS7B reduces GO3P to HXDG3P IEA Sus scrofa 73315 R-XTR-1483002 https://reactome.org/PathwayBrowser/#/R-XTR-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Xenopus tropicalis 73315 R-XTR-390427 https://reactome.org/PathwayBrowser/#/R-XTR-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Xenopus tropicalis 73315 R-XTR-75883 https://reactome.org/PathwayBrowser/#/R-XTR-75883 DHRS7B reduces GO3P to HXDG3P IEA Xenopus tropicalis 73316 R-BTA-111742 https://reactome.org/PathwayBrowser/#/R-BTA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 73316 R-BTA-111751 https://reactome.org/PathwayBrowser/#/R-BTA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 73316 R-BTA-111804 https://reactome.org/PathwayBrowser/#/R-BTA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 73316 R-BTA-8866405 https://reactome.org/PathwayBrowser/#/R-BTA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 73316 R-CEL-111742 https://reactome.org/PathwayBrowser/#/R-CEL-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 73316 R-CEL-111751 https://reactome.org/PathwayBrowser/#/R-CEL-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 73316 R-CEL-111804 https://reactome.org/PathwayBrowser/#/R-CEL-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 73316 R-CEL-8866405 https://reactome.org/PathwayBrowser/#/R-CEL-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 73316 R-CFA-111742 https://reactome.org/PathwayBrowser/#/R-CFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 73316 R-CFA-111751 https://reactome.org/PathwayBrowser/#/R-CFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 73316 R-CFA-111804 https://reactome.org/PathwayBrowser/#/R-CFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 73316 R-CFA-8866405 https://reactome.org/PathwayBrowser/#/R-CFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 73316 R-DDI-111751 https://reactome.org/PathwayBrowser/#/R-DDI-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 73316 R-DDI-111804 https://reactome.org/PathwayBrowser/#/R-DDI-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 73316 R-DME-111751 https://reactome.org/PathwayBrowser/#/R-DME-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 73316 R-DME-111804 https://reactome.org/PathwayBrowser/#/R-DME-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 73316 R-DRE-111742 https://reactome.org/PathwayBrowser/#/R-DRE-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 73316 R-DRE-111751 https://reactome.org/PathwayBrowser/#/R-DRE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 73316 R-DRE-111804 https://reactome.org/PathwayBrowser/#/R-DRE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 73316 R-DRE-8866405 https://reactome.org/PathwayBrowser/#/R-DRE-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 73316 R-HSA-111742 https://reactome.org/PathwayBrowser/#/R-HSA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 73316 R-HSA-111751 https://reactome.org/PathwayBrowser/#/R-HSA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 73316 R-HSA-111804 https://reactome.org/PathwayBrowser/#/R-HSA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 73316 R-HSA-8866405 https://reactome.org/PathwayBrowser/#/R-HSA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 73316 R-MMU-111742 https://reactome.org/PathwayBrowser/#/R-MMU-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 73316 R-MMU-111751 https://reactome.org/PathwayBrowser/#/R-MMU-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 73316 R-MMU-111804 https://reactome.org/PathwayBrowser/#/R-MMU-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 73316 R-MMU-8866405 https://reactome.org/PathwayBrowser/#/R-MMU-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 73316 R-PFA-111742 https://reactome.org/PathwayBrowser/#/R-PFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 73316 R-PFA-111751 https://reactome.org/PathwayBrowser/#/R-PFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 73316 R-PFA-111804 https://reactome.org/PathwayBrowser/#/R-PFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 73316 R-PFA-8866405 https://reactome.org/PathwayBrowser/#/R-PFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 73316 R-RNO-111742 https://reactome.org/PathwayBrowser/#/R-RNO-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 73316 R-RNO-111751 https://reactome.org/PathwayBrowser/#/R-RNO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 73316 R-RNO-111804 https://reactome.org/PathwayBrowser/#/R-RNO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 73316 R-RNO-8866405 https://reactome.org/PathwayBrowser/#/R-RNO-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 73316 R-SCE-111751 https://reactome.org/PathwayBrowser/#/R-SCE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 73316 R-SCE-111804 https://reactome.org/PathwayBrowser/#/R-SCE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 73316 R-SPO-111751 https://reactome.org/PathwayBrowser/#/R-SPO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 73316 R-SPO-111804 https://reactome.org/PathwayBrowser/#/R-SPO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 73316 R-SSC-111742 https://reactome.org/PathwayBrowser/#/R-SSC-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 73316 R-SSC-111751 https://reactome.org/PathwayBrowser/#/R-SSC-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 73316 R-SSC-111804 https://reactome.org/PathwayBrowser/#/R-SSC-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 73316 R-SSC-8866405 https://reactome.org/PathwayBrowser/#/R-SSC-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 73316 R-XTR-111742 https://reactome.org/PathwayBrowser/#/R-XTR-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 73316 R-XTR-8866405 https://reactome.org/PathwayBrowser/#/R-XTR-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 73542 R-HSA-6782859 https://reactome.org/PathwayBrowser/#/R-HSA-6782859 TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 73542 R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 73542 R-HSA-6786621 https://reactome.org/PathwayBrowser/#/R-HSA-6786621 TRMT10A methylates guanosine-9 in tRNA IEA Homo sapiens 73542 R-HSA-6787591 https://reactome.org/PathwayBrowser/#/R-HSA-6787591 TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9 TAS Homo sapiens 73542 R-SCE-6783396 https://reactome.org/PathwayBrowser/#/R-SCE-6783396 TRM5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 73542 R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 73542 R-SCE-6786632 https://reactome.org/PathwayBrowser/#/R-SCE-6786632 TRM10 methylates guanosine-9 in tRNA TAS Saccharomyces cerevisiae 73543 R-HSA-6782879 https://reactome.org/PathwayBrowser/#/R-HSA-6782879 TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 73543 R-HSA-6782881 https://reactome.org/PathwayBrowser/#/R-HSA-6782881 LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 73543 R-HSA-6783455 https://reactome.org/PathwayBrowser/#/R-HSA-6783455 TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 73543 R-SCE-6783417 https://reactome.org/PathwayBrowser/#/R-SCE-6783417 PPM2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 73543 R-SCE-6783426 https://reactome.org/PathwayBrowser/#/R-SCE-6783426 TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 73544 R-HSA-6782890 https://reactome.org/PathwayBrowser/#/R-HSA-6782890 LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 73544 R-SCE-6783393 https://reactome.org/PathwayBrowser/#/R-SCE-6783393 PPM2 methoxycarbonylates yW-58 yielding yW at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 73550 R-HSA-6782879 https://reactome.org/PathwayBrowser/#/R-HSA-6782879 TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 73550 R-HSA-6782893 https://reactome.org/PathwayBrowser/#/R-HSA-6782893 TRMT12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 73550 R-SCE-6783410 https://reactome.org/PathwayBrowser/#/R-SCE-6783410 TRM12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 73550 R-SCE-6783426 https://reactome.org/PathwayBrowser/#/R-SCE-6783426 TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 73602 R-HSA-6783473 https://reactome.org/PathwayBrowser/#/R-HSA-6783473 LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 73603 R-HSA-6783455 https://reactome.org/PathwayBrowser/#/R-HSA-6783455 TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 73603 R-HSA-6783473 https://reactome.org/PathwayBrowser/#/R-HSA-6783473 LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 73687 R-HSA-6784494 https://reactome.org/PathwayBrowser/#/R-HSA-6784494 EKC complex threonylcarbamoylates A37 of tRNAs IEA Homo sapiens 73687 R-SCE-6784469 https://reactome.org/PathwayBrowser/#/R-SCE-6784469 EKC/KEOPS complex threonylcarbamoylates adenosine-37 of tRNAs TAS Saccharomyces cerevisiae 73747 R-HSA-6782264 https://reactome.org/PathwayBrowser/#/R-HSA-6782264 CTU1:CTU2:URM1 thiolates uridine-34 in tRNAs TAS Homo sapiens 73747 R-HSA-6782296 https://reactome.org/PathwayBrowser/#/R-HSA-6782296 DUS2:EPRS reduces uridine to dihydrouridine in tRNAs IEA Homo sapiens 73747 R-HSA-6782381 https://reactome.org/PathwayBrowser/#/R-HSA-6782381 PUS1 isoform 2 transforms uridine residues to pseudouridine in the anticodon stems of tRNAs IEA Homo sapiens 73747 R-HSA-6786583 https://reactome.org/PathwayBrowser/#/R-HSA-6786583 PUS7 transforms uridine to pseudouridine in tRNAs IEA Homo sapiens 73747 R-HSA-6787403 https://reactome.org/PathwayBrowser/#/R-HSA-6787403 GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA IEA Homo sapiens 73747 R-HSA-6787566 https://reactome.org/PathwayBrowser/#/R-HSA-6787566 PUS1 isoform 1 transforms uridine-27, uridine-28 yielding pseudouridine in tRNA(Lys,Ser) TAS Homo sapiens 73747 R-HSA-6788707 https://reactome.org/PathwayBrowser/#/R-HSA-6788707 TRMT44 2'-O-methylates uridine-44 in tRNA(Ser) IEA Homo sapiens 73747 R-HSA-8870289 https://reactome.org/PathwayBrowser/#/R-HSA-8870289 PUS3 transforms uridine-39 to pseudouridine-39 in tRNA TAS Homo sapiens 73747 R-HSA-8941312 https://reactome.org/PathwayBrowser/#/R-HSA-8941312 TUT4,TUT7 oligouridylate mRNA IEA Homo sapiens 73747 R-HSA-9817512 https://reactome.org/PathwayBrowser/#/R-HSA-9817512 UNG (UNG2) and base excision repair remove uridine and 5-methylcytidine from chromatin containing histone H3.3 IEA Homo sapiens 73747 R-HSA-9817513 https://reactome.org/PathwayBrowser/#/R-HSA-9817513 AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine IEA Homo sapiens 73747 R-HSA-9820887 https://reactome.org/PathwayBrowser/#/R-HSA-9820887 PABPN1 binds oligouridylated mRNA IEA Homo sapiens 73747 R-HSA-9820895 https://reactome.org/PathwayBrowser/#/R-HSA-9820895 DIS3L2 binds PABPN1 in PABPN1:uridylated mRNA complex IEA Homo sapiens 73747 R-HSA-9822437 https://reactome.org/PathwayBrowser/#/R-HSA-9822437 DIS3L2 hydrolyzes uridylated mRNA IEA Homo sapiens 73747 R-MMU-9817520 https://reactome.org/PathwayBrowser/#/R-MMU-9817520 Aicda deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine TAS Mus musculus 73747 R-MMU-9817522 https://reactome.org/PathwayBrowser/#/R-MMU-9817522 Ung (Ung2) and base excision repair remove uridine and 5-methylcytidine from chromatin containing histone H3.3 TAS Mus musculus 73747 R-MMU-9820839 https://reactome.org/PathwayBrowser/#/R-MMU-9820839 Dis3l2 binds Pabpn1 in Pabpn1:uridylated mRNA complex TAS Mus musculus 73747 R-MMU-9820880 https://reactome.org/PathwayBrowser/#/R-MMU-9820880 Pabpn1 binds oligouridylated mRNA TAS Mus musculus 73747 R-MMU-9820884 https://reactome.org/PathwayBrowser/#/R-MMU-9820884 Tut4,Tut7 oligouridylate mRNA TAS Mus musculus 73747 R-MMU-9822432 https://reactome.org/PathwayBrowser/#/R-MMU-9822432 Dis3l2 hydrolyzes uridylated mRNA TAS Mus musculus 73747 R-SCE-6786558 https://reactome.org/PathwayBrowser/#/R-SCE-6786558 PUS7 transforms uridine to pseudouridine at nucleotide 13 of tRNA TAS Saccharomyces cerevisiae 73747 R-SCE-6787377 https://reactome.org/PathwayBrowser/#/R-SCE-6787377 MSS1 and MTO1 transform uridine-34 to 5-carboxymethylaminomethyluridine-34 in tRNA TAS Saccharomyces cerevisiae 73747 R-SCE-6788673 https://reactome.org/PathwayBrowser/#/R-SCE-6788673 TRM44 2'-O-methylates uridine-44 in tRNA(Ser) TAS Saccharomyces cerevisiae 73747 R-SCE-6790127 https://reactome.org/PathwayBrowser/#/R-SCE-6790127 SMM1 (DUS2) reduces uridine-20 to dihydrouridine in tRNA(Leu) TAS Saccharomyces cerevisiae 73747 R-SCE-6790166 https://reactome.org/PathwayBrowser/#/R-SCE-6790166 PUS1 transforms uridine residues to pseudouridine in unspliced tRNA(Ile,Tyr) TAS Saccharomyces cerevisiae 73927 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 73927 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 73927 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 73927 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 73927 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 73927 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 73927 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 73927 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 73927 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 73927 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 73927 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 73979 R-HSA-5333612 https://reactome.org/PathwayBrowser/#/R-HSA-5333612 MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal IEA Homo sapiens 73979 R-RNO-5333613 https://reactome.org/PathwayBrowser/#/R-RNO-5333613 MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal TAS Rattus norvegicus 73980 R-BTA-390250 https://reactome.org/PathwayBrowser/#/R-BTA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Bos taurus 73980 R-BTA-390251 https://reactome.org/PathwayBrowser/#/R-BTA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 73980 R-BTA-6809264 https://reactome.org/PathwayBrowser/#/R-BTA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 73980 R-CEL-390251 https://reactome.org/PathwayBrowser/#/R-CEL-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 73980 R-CEL-6809264 https://reactome.org/PathwayBrowser/#/R-CEL-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 73980 R-CFA-390250 https://reactome.org/PathwayBrowser/#/R-CFA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Canis familiaris 73980 R-CFA-390251 https://reactome.org/PathwayBrowser/#/R-CFA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 73980 R-CFA-6809264 https://reactome.org/PathwayBrowser/#/R-CFA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 73980 R-DDI-390250 https://reactome.org/PathwayBrowser/#/R-DDI-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Dictyostelium discoideum 73980 R-DDI-390251 https://reactome.org/PathwayBrowser/#/R-DDI-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Dictyostelium discoideum 73980 R-DME-390251 https://reactome.org/PathwayBrowser/#/R-DME-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Drosophila melanogaster 73980 R-DRE-390250 https://reactome.org/PathwayBrowser/#/R-DRE-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Danio rerio 73980 R-DRE-6809264 https://reactome.org/PathwayBrowser/#/R-DRE-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Danio rerio 73980 R-GGA-390250 https://reactome.org/PathwayBrowser/#/R-GGA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Gallus gallus 73980 R-GGA-390251 https://reactome.org/PathwayBrowser/#/R-GGA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 73980 R-GGA-6809264 https://reactome.org/PathwayBrowser/#/R-GGA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 73980 R-HSA-390250 https://reactome.org/PathwayBrowser/#/R-HSA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA TAS Homo sapiens 73980 R-HSA-390251 https://reactome.org/PathwayBrowser/#/R-HSA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 73980 R-HSA-548830 https://reactome.org/PathwayBrowser/#/R-HSA-548830 ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA IEA Homo sapiens 73980 R-HSA-6809264 https://reactome.org/PathwayBrowser/#/R-HSA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 73980 R-MMU-390250 https://reactome.org/PathwayBrowser/#/R-MMU-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Mus musculus 73980 R-MMU-390251 https://reactome.org/PathwayBrowser/#/R-MMU-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 73980 R-MMU-548848 https://reactome.org/PathwayBrowser/#/R-MMU-548848 lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4] TAS Mus musculus 73980 R-MMU-6809264 https://reactome.org/PathwayBrowser/#/R-MMU-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 73980 R-RNO-390250 https://reactome.org/PathwayBrowser/#/R-RNO-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Rattus norvegicus 73980 R-RNO-390251 https://reactome.org/PathwayBrowser/#/R-RNO-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 73980 R-RNO-6809264 https://reactome.org/PathwayBrowser/#/R-RNO-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 73980 R-SCE-390250 https://reactome.org/PathwayBrowser/#/R-SCE-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Saccharomyces cerevisiae 73980 R-SSC-390250 https://reactome.org/PathwayBrowser/#/R-SSC-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Sus scrofa 73980 R-SSC-6809264 https://reactome.org/PathwayBrowser/#/R-SSC-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Sus scrofa 73980 R-XTR-390250 https://reactome.org/PathwayBrowser/#/R-XTR-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA IEA Xenopus tropicalis 73980 R-XTR-6809264 https://reactome.org/PathwayBrowser/#/R-XTR-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Xenopus tropicalis 74035 R-BTA-111437 https://reactome.org/PathwayBrowser/#/R-BTA-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Bos taurus 74035 R-BTA-111438 https://reactome.org/PathwayBrowser/#/R-BTA-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Bos taurus 74035 R-BTA-75079 https://reactome.org/PathwayBrowser/#/R-BTA-75079 Formation of AT-AC C complex IEA Bos taurus 74035 R-BTA-75081 https://reactome.org/PathwayBrowser/#/R-BTA-75081 Formation of AT-AC B Complex IEA Bos taurus 74035 R-BTA-75082 https://reactome.org/PathwayBrowser/#/R-BTA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Bos taurus 74035 R-BTA-75083 https://reactome.org/PathwayBrowser/#/R-BTA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Bos taurus 74035 R-BTA-77585 https://reactome.org/PathwayBrowser/#/R-BTA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Bos taurus 74035 R-BTA-77586 https://reactome.org/PathwayBrowser/#/R-BTA-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Bos taurus 74035 R-CEL-111437 https://reactome.org/PathwayBrowser/#/R-CEL-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Caenorhabditis elegans 74035 R-CEL-111438 https://reactome.org/PathwayBrowser/#/R-CEL-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Caenorhabditis elegans 74035 R-CEL-75079 https://reactome.org/PathwayBrowser/#/R-CEL-75079 Formation of AT-AC C complex IEA Caenorhabditis elegans 74035 R-CEL-75081 https://reactome.org/PathwayBrowser/#/R-CEL-75081 Formation of AT-AC B Complex IEA Caenorhabditis elegans 74035 R-CEL-75082 https://reactome.org/PathwayBrowser/#/R-CEL-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Caenorhabditis elegans 74035 R-CEL-77585 https://reactome.org/PathwayBrowser/#/R-CEL-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Caenorhabditis elegans 74035 R-CEL-77586 https://reactome.org/PathwayBrowser/#/R-CEL-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Caenorhabditis elegans 74035 R-CFA-111437 https://reactome.org/PathwayBrowser/#/R-CFA-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Canis familiaris 74035 R-CFA-111438 https://reactome.org/PathwayBrowser/#/R-CFA-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Canis familiaris 74035 R-CFA-75079 https://reactome.org/PathwayBrowser/#/R-CFA-75079 Formation of AT-AC C complex IEA Canis familiaris 74035 R-CFA-75081 https://reactome.org/PathwayBrowser/#/R-CFA-75081 Formation of AT-AC B Complex IEA Canis familiaris 74035 R-CFA-75082 https://reactome.org/PathwayBrowser/#/R-CFA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Canis familiaris 74035 R-CFA-75083 https://reactome.org/PathwayBrowser/#/R-CFA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Canis familiaris 74035 R-CFA-77585 https://reactome.org/PathwayBrowser/#/R-CFA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Canis familiaris 74035 R-CFA-77586 https://reactome.org/PathwayBrowser/#/R-CFA-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Canis familiaris 74035 R-DDI-111437 https://reactome.org/PathwayBrowser/#/R-DDI-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Dictyostelium discoideum 74035 R-DDI-111438 https://reactome.org/PathwayBrowser/#/R-DDI-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Dictyostelium discoideum 74035 R-DDI-77585 https://reactome.org/PathwayBrowser/#/R-DDI-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Dictyostelium discoideum 74035 R-DDI-77586 https://reactome.org/PathwayBrowser/#/R-DDI-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Dictyostelium discoideum 74035 R-DME-111437 https://reactome.org/PathwayBrowser/#/R-DME-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Drosophila melanogaster 74035 R-DME-111438 https://reactome.org/PathwayBrowser/#/R-DME-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Drosophila melanogaster 74035 R-DME-75079 https://reactome.org/PathwayBrowser/#/R-DME-75079 Formation of AT-AC C complex IEA Drosophila melanogaster 74035 R-DME-75081 https://reactome.org/PathwayBrowser/#/R-DME-75081 Formation of AT-AC B Complex IEA Drosophila melanogaster 74035 R-DME-75082 https://reactome.org/PathwayBrowser/#/R-DME-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Drosophila melanogaster 74035 R-DME-77585 https://reactome.org/PathwayBrowser/#/R-DME-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Drosophila melanogaster 74035 R-DME-77586 https://reactome.org/PathwayBrowser/#/R-DME-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Drosophila melanogaster 74035 R-GGA-111437 https://reactome.org/PathwayBrowser/#/R-GGA-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Gallus gallus 74035 R-GGA-111438 https://reactome.org/PathwayBrowser/#/R-GGA-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Gallus gallus 74035 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus 74035 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus 74035 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus 74035 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus 74035 R-GGA-77585 https://reactome.org/PathwayBrowser/#/R-GGA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Gallus gallus 74035 R-GGA-77586 https://reactome.org/PathwayBrowser/#/R-GGA-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Gallus gallus 74035 R-HSA-111437 https://reactome.org/PathwayBrowser/#/R-HSA-111437 Cleavage of the 3'-end of the Histone Pre-mRNA TAS Homo sapiens 74035 R-HSA-111438 https://reactome.org/PathwayBrowser/#/R-HSA-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA TAS Homo sapiens 74035 R-HSA-6814549 https://reactome.org/PathwayBrowser/#/R-HSA-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding TAS Homo sapiens 74035 R-HSA-6814555 https://reactome.org/PathwayBrowser/#/R-HSA-6814555 Integrator complex processes the 3' end of snRNA TAS Homo sapiens 74035 R-HSA-6814559 https://reactome.org/PathwayBrowser/#/R-HSA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine TAS Homo sapiens 74035 R-HSA-6814885 https://reactome.org/PathwayBrowser/#/R-HSA-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA TAS Homo sapiens 74035 R-HSA-75079 https://reactome.org/PathwayBrowser/#/R-HSA-75079 Formation of AT-AC C complex TAS Homo sapiens 74035 R-HSA-75081 https://reactome.org/PathwayBrowser/#/R-HSA-75081 Formation of AT-AC B Complex TAS Homo sapiens 74035 R-HSA-75082 https://reactome.org/PathwayBrowser/#/R-HSA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage TAS Homo sapiens 74035 R-HSA-75083 https://reactome.org/PathwayBrowser/#/R-HSA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation TAS Homo sapiens 74035 R-HSA-77585 https://reactome.org/PathwayBrowser/#/R-HSA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA TAS Homo sapiens 74035 R-HSA-77586 https://reactome.org/PathwayBrowser/#/R-HSA-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA TAS Homo sapiens 74035 R-MMU-111437 https://reactome.org/PathwayBrowser/#/R-MMU-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Mus musculus 74035 R-MMU-111438 https://reactome.org/PathwayBrowser/#/R-MMU-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Mus musculus 74035 R-MMU-75079 https://reactome.org/PathwayBrowser/#/R-MMU-75079 Formation of AT-AC C complex IEA Mus musculus 74035 R-MMU-75081 https://reactome.org/PathwayBrowser/#/R-MMU-75081 Formation of AT-AC B Complex IEA Mus musculus 74035 R-MMU-75082 https://reactome.org/PathwayBrowser/#/R-MMU-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Mus musculus 74035 R-MMU-75083 https://reactome.org/PathwayBrowser/#/R-MMU-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Mus musculus 74035 R-MMU-77585 https://reactome.org/PathwayBrowser/#/R-MMU-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Mus musculus 74035 R-MMU-77586 https://reactome.org/PathwayBrowser/#/R-MMU-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Mus musculus 74035 R-RNO-111437 https://reactome.org/PathwayBrowser/#/R-RNO-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Rattus norvegicus 74035 R-RNO-111438 https://reactome.org/PathwayBrowser/#/R-RNO-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Rattus norvegicus 74035 R-RNO-75079 https://reactome.org/PathwayBrowser/#/R-RNO-75079 Formation of AT-AC C complex IEA Rattus norvegicus 74035 R-RNO-75081 https://reactome.org/PathwayBrowser/#/R-RNO-75081 Formation of AT-AC B Complex IEA Rattus norvegicus 74035 R-RNO-75082 https://reactome.org/PathwayBrowser/#/R-RNO-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Rattus norvegicus 74035 R-RNO-75083 https://reactome.org/PathwayBrowser/#/R-RNO-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Rattus norvegicus 74035 R-RNO-77585 https://reactome.org/PathwayBrowser/#/R-RNO-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Rattus norvegicus 74035 R-RNO-77586 https://reactome.org/PathwayBrowser/#/R-RNO-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Rattus norvegicus 74035 R-SSC-111437 https://reactome.org/PathwayBrowser/#/R-SSC-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Sus scrofa 74035 R-SSC-111438 https://reactome.org/PathwayBrowser/#/R-SSC-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Sus scrofa 74035 R-SSC-75079 https://reactome.org/PathwayBrowser/#/R-SSC-75079 Formation of AT-AC C complex IEA Sus scrofa 74035 R-SSC-75081 https://reactome.org/PathwayBrowser/#/R-SSC-75081 Formation of AT-AC B Complex IEA Sus scrofa 74035 R-SSC-75082 https://reactome.org/PathwayBrowser/#/R-SSC-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Sus scrofa 74035 R-SSC-75083 https://reactome.org/PathwayBrowser/#/R-SSC-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Sus scrofa 74035 R-SSC-77585 https://reactome.org/PathwayBrowser/#/R-SSC-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Sus scrofa 74035 R-SSC-77586 https://reactome.org/PathwayBrowser/#/R-SSC-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Sus scrofa 74035 R-XTR-111437 https://reactome.org/PathwayBrowser/#/R-XTR-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Xenopus tropicalis 74035 R-XTR-111438 https://reactome.org/PathwayBrowser/#/R-XTR-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Xenopus tropicalis 74035 R-XTR-75079 https://reactome.org/PathwayBrowser/#/R-XTR-75079 Formation of AT-AC C complex IEA Xenopus tropicalis 74035 R-XTR-75081 https://reactome.org/PathwayBrowser/#/R-XTR-75081 Formation of AT-AC B Complex IEA Xenopus tropicalis 74035 R-XTR-75082 https://reactome.org/PathwayBrowser/#/R-XTR-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Xenopus tropicalis 74035 R-XTR-75083 https://reactome.org/PathwayBrowser/#/R-XTR-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Xenopus tropicalis 74035 R-XTR-77585 https://reactome.org/PathwayBrowser/#/R-XTR-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Xenopus tropicalis 74035 R-XTR-77586 https://reactome.org/PathwayBrowser/#/R-XTR-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Xenopus tropicalis 74275 R-HSA-6782881 https://reactome.org/PathwayBrowser/#/R-HSA-6782881 LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 74275 R-HSA-6782890 https://reactome.org/PathwayBrowser/#/R-HSA-6782890 LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 74275 R-SCE-6783393 https://reactome.org/PathwayBrowser/#/R-SCE-6783393 PPM2 methoxycarbonylates yW-58 yielding yW at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 74275 R-SCE-6783417 https://reactome.org/PathwayBrowser/#/R-SCE-6783417 PPM2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 74414 R-BTA-73618 https://reactome.org/PathwayBrowser/#/R-BTA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Bos taurus 74414 R-BTA-73620 https://reactome.org/PathwayBrowser/#/R-BTA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Bos taurus 74414 R-CEL-73618 https://reactome.org/PathwayBrowser/#/R-CEL-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Caenorhabditis elegans 74414 R-CEL-73620 https://reactome.org/PathwayBrowser/#/R-CEL-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Caenorhabditis elegans 74414 R-CFA-73618 https://reactome.org/PathwayBrowser/#/R-CFA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Canis familiaris 74414 R-CFA-73620 https://reactome.org/PathwayBrowser/#/R-CFA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Canis familiaris 74414 R-DDI-73618 https://reactome.org/PathwayBrowser/#/R-DDI-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Dictyostelium discoideum 74414 R-DDI-73620 https://reactome.org/PathwayBrowser/#/R-DDI-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Dictyostelium discoideum 74414 R-DME-73618 https://reactome.org/PathwayBrowser/#/R-DME-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Drosophila melanogaster 74414 R-DME-73620 https://reactome.org/PathwayBrowser/#/R-DME-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Drosophila melanogaster 74414 R-DRE-73618 https://reactome.org/PathwayBrowser/#/R-DRE-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Danio rerio 74414 R-DRE-73620 https://reactome.org/PathwayBrowser/#/R-DRE-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Danio rerio 74414 R-GGA-73618 https://reactome.org/PathwayBrowser/#/R-GGA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Gallus gallus 74414 R-GGA-73620 https://reactome.org/PathwayBrowser/#/R-GGA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Gallus gallus 74414 R-HSA-73618 https://reactome.org/PathwayBrowser/#/R-HSA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate TAS Homo sapiens 74414 R-HSA-73620 https://reactome.org/PathwayBrowser/#/R-HSA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 TAS Homo sapiens 74414 R-MMU-73618 https://reactome.org/PathwayBrowser/#/R-MMU-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Mus musculus 74414 R-MMU-73620 https://reactome.org/PathwayBrowser/#/R-MMU-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Mus musculus 74414 R-RNO-73618 https://reactome.org/PathwayBrowser/#/R-RNO-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Rattus norvegicus 74414 R-RNO-73620 https://reactome.org/PathwayBrowser/#/R-RNO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Rattus norvegicus 74414 R-SPO-73620 https://reactome.org/PathwayBrowser/#/R-SPO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Schizosaccharomyces pombe 74414 R-SSC-73618 https://reactome.org/PathwayBrowser/#/R-SSC-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Sus scrofa 74414 R-SSC-73620 https://reactome.org/PathwayBrowser/#/R-SSC-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Sus scrofa 74418 R-HSA-6784494 https://reactome.org/PathwayBrowser/#/R-HSA-6784494 EKC complex threonylcarbamoylates A37 of tRNAs IEA Homo sapiens 74418 R-HSA-6786571 https://reactome.org/PathwayBrowser/#/R-HSA-6786571 CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37 TAS Homo sapiens 74418 R-SCE-6784469 https://reactome.org/PathwayBrowser/#/R-SCE-6784469 EKC/KEOPS complex threonylcarbamoylates adenosine-37 of tRNAs TAS Saccharomyces cerevisiae 74420 R-HSA-6786571 https://reactome.org/PathwayBrowser/#/R-HSA-6786571 CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37 TAS Homo sapiens 74429 R-HSA-9678128 https://reactome.org/PathwayBrowser/#/R-HSA-9678128 Spike glycoprotein of SARS coronavirus binds ACE2 on host cell TAS Homo sapiens 74429 R-HSA-9684016 https://reactome.org/PathwayBrowser/#/R-HSA-9684016 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 74429 R-HSA-9684017 https://reactome.org/PathwayBrowser/#/R-HSA-9684017 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 74429 R-HSA-9684018 https://reactome.org/PathwayBrowser/#/R-HSA-9684018 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 74429 R-HSA-9684030 https://reactome.org/PathwayBrowser/#/R-HSA-9684030 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 74429 R-HSA-9684032 https://reactome.org/PathwayBrowser/#/R-HSA-9684032 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 74429 R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 74429 R-HSA-9685531 https://reactome.org/PathwayBrowser/#/R-HSA-9685531 SARS virus buds into ERGIC lumen TAS Homo sapiens 74429 R-HSA-9685542 https://reactome.org/PathwayBrowser/#/R-HSA-9685542 Viral release TAS Homo sapiens 74429 R-HSA-9686699 https://reactome.org/PathwayBrowser/#/R-HSA-9686699 Fusion and Release of SARS-CoV-1 Nucleocapsid TAS Homo sapiens 74429 R-HSA-9686709 https://reactome.org/PathwayBrowser/#/R-HSA-9686709 Uncoating of SARS-CoV-1 Genome TAS Homo sapiens 74429 R-HSA-9686710 https://reactome.org/PathwayBrowser/#/R-HSA-9686710 Cleavage of S protein into S1:S2 TAS Homo sapiens 74429 R-HSA-9686711 https://reactome.org/PathwayBrowser/#/R-HSA-9686711 Endocytois of SARS-CoV-1 Virion TAS Homo sapiens 74429 R-HSA-9686731 https://reactome.org/PathwayBrowser/#/R-HSA-9686731 TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 74429 R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 74429 R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 74429 R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 74429 R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 74429 R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 74429 R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 74429 R-HSA-9756603 https://reactome.org/PathwayBrowser/#/R-HSA-9756603 SARS-CoV-1 S binds SFTPD 12mer TAS Homo sapiens 7444 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 7444 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 7444 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 7444 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 7444 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 7444 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 7444 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 7444 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 7444 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 7444 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 7444 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 7444 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 7444 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 7444 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 7444 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 7444 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 7444 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 7444 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 7444 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 7444 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 7444 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 7444 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 7444 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 7444 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 7444 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 7444 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 7444 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 7444 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 7444 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 7444 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 7444 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 7444 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 7444 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 7444 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 7444 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 7444 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 7444 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 74443 R-HSA-6782296 https://reactome.org/PathwayBrowser/#/R-HSA-6782296 DUS2:EPRS reduces uridine to dihydrouridine in tRNAs IEA Homo sapiens 74443 R-SCE-6790127 https://reactome.org/PathwayBrowser/#/R-SCE-6790127 SMM1 (DUS2) reduces uridine-20 to dihydrouridine in tRNA(Leu) TAS Saccharomyces cerevisiae 74445 R-HSA-6790907 https://reactome.org/PathwayBrowser/#/R-HSA-6790907 Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides IEA Homo sapiens 74445 R-HSA-6793096 https://reactome.org/PathwayBrowser/#/R-HSA-6793096 MRM3 (RNMTL1) methylates guanosine-1370 of 16S rRNA yielding 2'-O-methylguanosine-1370 TAS Homo sapiens 74445 R-HSA-6793122 https://reactome.org/PathwayBrowser/#/R-HSA-6793122 MRM1 methylates guanosine-1145 of 16S rRNA yielding 2'-O-methylguanosine-1145 TAS Homo sapiens 74445 R-HSA-9024161 https://reactome.org/PathwayBrowser/#/R-HSA-9024161 FTSJ1 2'-O-methylates guanosine-34 in tRNA(Phe) TAS Homo sapiens 74445 R-SCE-6793739 https://reactome.org/PathwayBrowser/#/R-SCE-6793739 Box C/D snoRNP methylates ribonucleotides in pre-rRNA TAS Saccharomyces cerevisiae 74477 R-HSA-6788668 https://reactome.org/PathwayBrowser/#/R-HSA-6788668 TRMT13 2'-O-methylates adenosine-4 in tRNA IEA Homo sapiens 74477 R-HSA-6790907 https://reactome.org/PathwayBrowser/#/R-HSA-6790907 Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides IEA Homo sapiens 74477 R-SCE-6788665 https://reactome.org/PathwayBrowser/#/R-SCE-6788665 TRM13 2'-O-methylates adenosine-4 in tRNA TAS Saccharomyces cerevisiae 74477 R-SCE-6793739 https://reactome.org/PathwayBrowser/#/R-SCE-6793739 Box C/D snoRNP methylates ribonucleotides in pre-rRNA TAS Saccharomyces cerevisiae 74478 R-HSA-6788707 https://reactome.org/PathwayBrowser/#/R-HSA-6788707 TRMT44 2'-O-methylates uridine-44 in tRNA(Ser) IEA Homo sapiens 74478 R-HSA-6790907 https://reactome.org/PathwayBrowser/#/R-HSA-6790907 Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides IEA Homo sapiens 74478 R-HSA-6793127 https://reactome.org/PathwayBrowser/#/R-HSA-6793127 MRM2 (FTSJ2) methylates uridine-1369 of 16S rRNA yielding 2'-O-methyluridine TAS Homo sapiens 74478 R-SCE-6788673 https://reactome.org/PathwayBrowser/#/R-SCE-6788673 TRM44 2'-O-methylates uridine-44 in tRNA(Ser) TAS Saccharomyces cerevisiae 74478 R-SCE-6793739 https://reactome.org/PathwayBrowser/#/R-SCE-6793739 Box C/D snoRNP methylates ribonucleotides in pre-rRNA TAS Saccharomyces cerevisiae 74480 R-HSA-6782286 https://reactome.org/PathwayBrowser/#/R-HSA-6782286 METTL1:WDR4 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 IEA Homo sapiens 74480 R-SCE-6790175 https://reactome.org/PathwayBrowser/#/R-SCE-6790175 TRM8:TRM82 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 TAS Saccharomyces cerevisiae 74481 R-HSA-6786501 https://reactome.org/PathwayBrowser/#/R-HSA-6786501 TRMT11:TRMT112 methylates guanosine-10 in tRNA IEA Homo sapiens 74481 R-SCE-6786492 https://reactome.org/PathwayBrowser/#/R-SCE-6786492 TRM11:TRM112 methylates guanosine-10 in tRNA yielding N(2)-methylguanosine-10 TAS Saccharomyces cerevisiae 74483 R-HSA-6782388 https://reactome.org/PathwayBrowser/#/R-HSA-6782388 NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) IEA Homo sapiens 74483 R-HSA-6782419 https://reactome.org/PathwayBrowser/#/R-HSA-6782419 TRDMT1 (DNMT2) methylates cytidine-38 of tRNA(Asp) TAS Homo sapiens 74483 R-HSA-6785409 https://reactome.org/PathwayBrowser/#/R-HSA-6785409 NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) IEA Homo sapiens 74483 R-HSA-6785438 https://reactome.org/PathwayBrowser/#/R-HSA-6785438 NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) TAS Homo sapiens 74483 R-HSA-6790944 https://reactome.org/PathwayBrowser/#/R-HSA-6790944 NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447 IEA Homo sapiens 74483 R-HSA-6793057 https://reactome.org/PathwayBrowser/#/R-HSA-6793057 NSUN4 methylates cytidine-841 of 12S rRNA yielding 5-methylcytidine-841 TAS Homo sapiens 74483 R-HSA-8932765 https://reactome.org/PathwayBrowser/#/R-HSA-8932765 NSUN6 methylates cytidine-72 in tRNA(Cys) and tRNA(Thr) TAS Homo sapiens 74483 R-SCE-6790149 https://reactome.org/PathwayBrowser/#/R-SCE-6790149 NCL1 (TRM4) methylates cytidine-49 of tRNA(Asp) yielding 5-methylcytidine-46 TAS Saccharomyces cerevisiae 74483 R-SCE-6790189 https://reactome.org/PathwayBrowser/#/R-SCE-6790189 NCL1 (TRM4) methylates cytidine-34 of unspliced tRNA(Leu) yielding 5-methylcytidine-34 TAS Saccharomyces cerevisiae 74483 R-SCE-6790942 https://reactome.org/PathwayBrowser/#/R-SCE-6790942 NOP2 methylates cytosine-2870 of 25S rRNA yielding 5-methylcytosine-2870 TAS Saccharomyces cerevisiae 74491 R-HSA-6783492 https://reactome.org/PathwayBrowser/#/R-HSA-6783492 TRMT6:TRMT61A methylate adenosine yielding 1-methyladenosine at nucleotide 58 of tRNA(Met) TAS Homo sapiens 74491 R-HSA-6787525 https://reactome.org/PathwayBrowser/#/R-HSA-6787525 TRMT61B methylates adenosine-58 in tRNA yielding 1-methyladenosine-58 TAS Homo sapiens 74491 R-HSA-6787594 https://reactome.org/PathwayBrowser/#/R-HSA-6787594 TRMT10C:HSD17B10 (TRMT10C:SDR5C1) methylates adenosine-9 in tRNA yielding 1-methyladenosine-9 TAS Homo sapiens 74493 R-HSA-6790994 https://reactome.org/PathwayBrowser/#/R-HSA-6790994 DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851 TAS Homo sapiens 74495 R-HSA-6788684 https://reactome.org/PathwayBrowser/#/R-HSA-6788684 TRMT13 2'-O-methylates cytidine-4 in tRNA IEA Homo sapiens 74495 R-HSA-6790907 https://reactome.org/PathwayBrowser/#/R-HSA-6790907 Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides IEA Homo sapiens 74495 R-HSA-9024159 https://reactome.org/PathwayBrowser/#/R-HSA-9024159 FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe) TAS Homo sapiens 74495 R-SCE-6788683 https://reactome.org/PathwayBrowser/#/R-SCE-6788683 TRM13 2'-O-methylates cytidine-4 in tRNA TAS Saccharomyces cerevisiae 74495 R-SCE-6793739 https://reactome.org/PathwayBrowser/#/R-SCE-6793739 Box C/D snoRNP methylates ribonucleotides in pre-rRNA TAS Saccharomyces cerevisiae 74508 R-SCE-6787377 https://reactome.org/PathwayBrowser/#/R-SCE-6787377 MSS1 and MTO1 transform uridine-34 to 5-carboxymethylaminomethyluridine-34 in tRNA TAS Saccharomyces cerevisiae 74508 R-SCE-6787385 https://reactome.org/PathwayBrowser/#/R-SCE-6787385 SLM3 (MTO2, MTU1) transfers a sulfur atom to 5-carboxymethylaminomethyluridine-34 in tRNA TAS Saccharomyces cerevisiae 74513 R-HSA-6782416 https://reactome.org/PathwayBrowser/#/R-HSA-6782416 TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) TAS Homo sapiens 74851 R-HSA-6786500 https://reactome.org/PathwayBrowser/#/R-HSA-6786500 ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 IEA Homo sapiens 74851 R-HSA-6786567 https://reactome.org/PathwayBrowser/#/R-HSA-6786567 KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine TAS Homo sapiens 74851 R-SCE-6790171 https://reactome.org/PathwayBrowser/#/R-SCE-6790171 TRM9 methylates 5-carboxymethyluridine-34 in tRNA(Arg3) yielding 5-methoxycarbonylmethyluridine-34 TAS Saccharomyces cerevisiae 74882 R-HSA-6786500 https://reactome.org/PathwayBrowser/#/R-HSA-6786500 ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 IEA Homo sapiens 74882 R-HSA-6786567 https://reactome.org/PathwayBrowser/#/R-HSA-6786567 KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine TAS Homo sapiens 74882 R-SCE-6790171 https://reactome.org/PathwayBrowser/#/R-SCE-6790171 TRM9 methylates 5-carboxymethyluridine-34 in tRNA(Arg3) yielding 5-methoxycarbonylmethyluridine-34 TAS Saccharomyces cerevisiae 74890 R-SCE-6790936 https://reactome.org/PathwayBrowser/#/R-SCE-6790936 EMG1 of the SSU processome methylates pseudouridine-1191 of 18S rRNA yielding N(1)-methylpseudouridine-1191 TAS Saccharomyces cerevisiae 74946 R-BTA-1855157 https://reactome.org/PathwayBrowser/#/R-BTA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Bos taurus 74946 R-BTA-1855194 https://reactome.org/PathwayBrowser/#/R-BTA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Bos taurus 74946 R-BTA-1855216 https://reactome.org/PathwayBrowser/#/R-BTA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Bos taurus 74946 R-BTA-2023971 https://reactome.org/PathwayBrowser/#/R-BTA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 74946 R-BTA-2023973 https://reactome.org/PathwayBrowser/#/R-BTA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 74946 R-CEL-1855157 https://reactome.org/PathwayBrowser/#/R-CEL-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 74946 R-CEL-1855194 https://reactome.org/PathwayBrowser/#/R-CEL-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 74946 R-CEL-1855216 https://reactome.org/PathwayBrowser/#/R-CEL-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Caenorhabditis elegans 74946 R-CEL-2023971 https://reactome.org/PathwayBrowser/#/R-CEL-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 74946 R-CEL-2023973 https://reactome.org/PathwayBrowser/#/R-CEL-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 74946 R-CFA-1855157 https://reactome.org/PathwayBrowser/#/R-CFA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Canis familiaris 74946 R-CFA-1855194 https://reactome.org/PathwayBrowser/#/R-CFA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Canis familiaris 74946 R-CFA-1855216 https://reactome.org/PathwayBrowser/#/R-CFA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Canis familiaris 74946 R-CFA-2023971 https://reactome.org/PathwayBrowser/#/R-CFA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 74946 R-CFA-2023973 https://reactome.org/PathwayBrowser/#/R-CFA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 74946 R-DDI-1855157 https://reactome.org/PathwayBrowser/#/R-DDI-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 74946 R-DDI-1855194 https://reactome.org/PathwayBrowser/#/R-DDI-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 74946 R-DDI-2023971 https://reactome.org/PathwayBrowser/#/R-DDI-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 74946 R-DDI-2023973 https://reactome.org/PathwayBrowser/#/R-DDI-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 74946 R-DME-1855157 https://reactome.org/PathwayBrowser/#/R-DME-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 74946 R-DME-1855194 https://reactome.org/PathwayBrowser/#/R-DME-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 74946 R-DME-1855216 https://reactome.org/PathwayBrowser/#/R-DME-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Drosophila melanogaster 74946 R-DME-2023971 https://reactome.org/PathwayBrowser/#/R-DME-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 74946 R-DME-2023973 https://reactome.org/PathwayBrowser/#/R-DME-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 74946 R-DRE-1855157 https://reactome.org/PathwayBrowser/#/R-DRE-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Danio rerio 74946 R-DRE-1855194 https://reactome.org/PathwayBrowser/#/R-DRE-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Danio rerio 74946 R-DRE-2023971 https://reactome.org/PathwayBrowser/#/R-DRE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 74946 R-DRE-2023973 https://reactome.org/PathwayBrowser/#/R-DRE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 74946 R-GGA-1855157 https://reactome.org/PathwayBrowser/#/R-GGA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Gallus gallus 74946 R-GGA-1855194 https://reactome.org/PathwayBrowser/#/R-GGA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Gallus gallus 74946 R-GGA-1855216 https://reactome.org/PathwayBrowser/#/R-GGA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Gallus gallus 74946 R-GGA-2023971 https://reactome.org/PathwayBrowser/#/R-GGA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 74946 R-GGA-2023973 https://reactome.org/PathwayBrowser/#/R-GGA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 74946 R-HSA-1855157 https://reactome.org/PathwayBrowser/#/R-HSA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus TAS Homo sapiens 74946 R-HSA-1855194 https://reactome.org/PathwayBrowser/#/R-HSA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol TAS Homo sapiens 74946 R-HSA-1855212 https://reactome.org/PathwayBrowser/#/R-HSA-1855212 1/3-PP-IP5 transports from the cytosol to the nucleus TAS Homo sapiens 74946 R-HSA-1855216 https://reactome.org/PathwayBrowser/#/R-HSA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol TAS Homo sapiens 74946 R-HSA-2023971 https://reactome.org/PathwayBrowser/#/R-HSA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 74946 R-HSA-2023973 https://reactome.org/PathwayBrowser/#/R-HSA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 74946 R-MMU-1855157 https://reactome.org/PathwayBrowser/#/R-MMU-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Mus musculus 74946 R-MMU-1855194 https://reactome.org/PathwayBrowser/#/R-MMU-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Mus musculus 74946 R-MMU-1855216 https://reactome.org/PathwayBrowser/#/R-MMU-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Mus musculus 74946 R-MMU-2023971 https://reactome.org/PathwayBrowser/#/R-MMU-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 74946 R-MMU-2023973 https://reactome.org/PathwayBrowser/#/R-MMU-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 74946 R-PFA-1855157 https://reactome.org/PathwayBrowser/#/R-PFA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 74946 R-PFA-1855194 https://reactome.org/PathwayBrowser/#/R-PFA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 74946 R-PFA-1855216 https://reactome.org/PathwayBrowser/#/R-PFA-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Plasmodium falciparum 74946 R-RNO-1855157 https://reactome.org/PathwayBrowser/#/R-RNO-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Rattus norvegicus 74946 R-RNO-1855194 https://reactome.org/PathwayBrowser/#/R-RNO-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Rattus norvegicus 74946 R-RNO-1855216 https://reactome.org/PathwayBrowser/#/R-RNO-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Rattus norvegicus 74946 R-RNO-2023971 https://reactome.org/PathwayBrowser/#/R-RNO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 74946 R-RNO-2023973 https://reactome.org/PathwayBrowser/#/R-RNO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 74946 R-SCE-1855157 https://reactome.org/PathwayBrowser/#/R-SCE-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 74946 R-SCE-1855194 https://reactome.org/PathwayBrowser/#/R-SCE-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 74946 R-SCE-1855216 https://reactome.org/PathwayBrowser/#/R-SCE-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Saccharomyces cerevisiae 74946 R-SCE-2023971 https://reactome.org/PathwayBrowser/#/R-SCE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 74946 R-SCE-2023973 https://reactome.org/PathwayBrowser/#/R-SCE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 74946 R-SPO-1855157 https://reactome.org/PathwayBrowser/#/R-SPO-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 74946 R-SPO-1855194 https://reactome.org/PathwayBrowser/#/R-SPO-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 74946 R-SPO-1855216 https://reactome.org/PathwayBrowser/#/R-SPO-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Schizosaccharomyces pombe 74946 R-SPO-2023971 https://reactome.org/PathwayBrowser/#/R-SPO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 74946 R-SPO-2023973 https://reactome.org/PathwayBrowser/#/R-SPO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 74946 R-SSC-1855157 https://reactome.org/PathwayBrowser/#/R-SSC-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Sus scrofa 74946 R-SSC-1855194 https://reactome.org/PathwayBrowser/#/R-SSC-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Sus scrofa 74946 R-SSC-1855216 https://reactome.org/PathwayBrowser/#/R-SSC-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Sus scrofa 74946 R-SSC-2023971 https://reactome.org/PathwayBrowser/#/R-SSC-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 74946 R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 74946 R-XTR-1855157 https://reactome.org/PathwayBrowser/#/R-XTR-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 74946 R-XTR-1855194 https://reactome.org/PathwayBrowser/#/R-XTR-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 74946 R-XTR-1855216 https://reactome.org/PathwayBrowser/#/R-XTR-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Xenopus tropicalis 74946 R-XTR-2023971 https://reactome.org/PathwayBrowser/#/R-XTR-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 74946 R-XTR-2023973 https://reactome.org/PathwayBrowser/#/R-XTR-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 7496 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 7496 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 7496 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 7496 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 7496 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 7496 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 7496 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 7496 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 74986 R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus 74986 R-BTA-1605632 https://reactome.org/PathwayBrowser/#/R-BTA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Bos taurus 74986 R-BTA-1605724 https://reactome.org/PathwayBrowser/#/R-BTA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Bos taurus 74986 R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus 74986 R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus 74986 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 74986 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 74986 R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 74986 R-BTA-9842115 https://reactome.org/PathwayBrowser/#/R-BTA-9842115 PSAP(195-273) dimer binds PE IEA Bos taurus 74986 R-CEL-1605624 https://reactome.org/PathwayBrowser/#/R-CEL-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Caenorhabditis elegans 74986 R-CEL-1605632 https://reactome.org/PathwayBrowser/#/R-CEL-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Caenorhabditis elegans 74986 R-CEL-1605736 https://reactome.org/PathwayBrowser/#/R-CEL-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Caenorhabditis elegans 74986 R-CEL-1606312 https://reactome.org/PathwayBrowser/#/R-CEL-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Caenorhabditis elegans 74986 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 74986 R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 74986 R-CEL-9842115 https://reactome.org/PathwayBrowser/#/R-CEL-9842115 PSAP(195-273) dimer binds PE IEA Caenorhabditis elegans 74986 R-CFA-1605624 https://reactome.org/PathwayBrowser/#/R-CFA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Canis familiaris 74986 R-CFA-1605632 https://reactome.org/PathwayBrowser/#/R-CFA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Canis familiaris 74986 R-CFA-1605724 https://reactome.org/PathwayBrowser/#/R-CFA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Canis familiaris 74986 R-CFA-1605736 https://reactome.org/PathwayBrowser/#/R-CFA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Canis familiaris 74986 R-CFA-1606312 https://reactome.org/PathwayBrowser/#/R-CFA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Canis familiaris 74986 R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 74986 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 74986 R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 74986 R-CFA-9842115 https://reactome.org/PathwayBrowser/#/R-CFA-9842115 PSAP(195-273) dimer binds PE IEA Canis familiaris 74986 R-DDI-1605624 https://reactome.org/PathwayBrowser/#/R-DDI-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Dictyostelium discoideum 74986 R-DDI-1605632 https://reactome.org/PathwayBrowser/#/R-DDI-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Dictyostelium discoideum 74986 R-DDI-1605736 https://reactome.org/PathwayBrowser/#/R-DDI-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Dictyostelium discoideum 74986 R-DDI-1606312 https://reactome.org/PathwayBrowser/#/R-DDI-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Dictyostelium discoideum 74986 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 74986 R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 74986 R-DDI-9842115 https://reactome.org/PathwayBrowser/#/R-DDI-9842115 PSAP(195-273) dimer binds PE IEA Dictyostelium discoideum 74986 R-DME-1605624 https://reactome.org/PathwayBrowser/#/R-DME-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Drosophila melanogaster 74986 R-DME-1605632 https://reactome.org/PathwayBrowser/#/R-DME-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Drosophila melanogaster 74986 R-DME-1606312 https://reactome.org/PathwayBrowser/#/R-DME-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Drosophila melanogaster 74986 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 74986 R-DME-9842115 https://reactome.org/PathwayBrowser/#/R-DME-9842115 PSAP(195-273) dimer binds PE IEA Drosophila melanogaster 74986 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus 74986 R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus 74986 R-GGA-1605724 https://reactome.org/PathwayBrowser/#/R-GGA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Gallus gallus 74986 R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus 74986 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus 74986 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 74986 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 74986 R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 74986 R-GGA-9842115 https://reactome.org/PathwayBrowser/#/R-GGA-9842115 PSAP(195-273) dimer binds PE IEA Gallus gallus 74986 R-HSA-1605624 https://reactome.org/PathwayBrowser/#/R-HSA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 TAS Homo sapiens 74986 R-HSA-1605632 https://reactome.org/PathwayBrowser/#/R-HSA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE TAS Homo sapiens 74986 R-HSA-1605724 https://reactome.org/PathwayBrowser/#/R-HSA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE TAS Homo sapiens 74986 R-HSA-1605736 https://reactome.org/PathwayBrowser/#/R-HSA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE TAS Homo sapiens 74986 R-HSA-1606312 https://reactome.org/PathwayBrowser/#/R-HSA-1606312 GLB1 hydrolyzes SapB/C:LacCer TAS Homo sapiens 74986 R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 74986 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 74986 R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 74986 R-HSA-9842115 https://reactome.org/PathwayBrowser/#/R-HSA-9842115 PSAP(195-273) dimer binds PE TAS Homo sapiens 74986 R-MMU-1605624 https://reactome.org/PathwayBrowser/#/R-MMU-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Mus musculus 74986 R-MMU-1605632 https://reactome.org/PathwayBrowser/#/R-MMU-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Mus musculus 74986 R-MMU-1605724 https://reactome.org/PathwayBrowser/#/R-MMU-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Mus musculus 74986 R-MMU-1605736 https://reactome.org/PathwayBrowser/#/R-MMU-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Mus musculus 74986 R-MMU-1606312 https://reactome.org/PathwayBrowser/#/R-MMU-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Mus musculus 74986 R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 74986 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 74986 R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 74986 R-MMU-9842115 https://reactome.org/PathwayBrowser/#/R-MMU-9842115 PSAP(195-273) dimer binds PE IEA Mus musculus 74986 R-RNO-1605624 https://reactome.org/PathwayBrowser/#/R-RNO-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Rattus norvegicus 74986 R-RNO-1605632 https://reactome.org/PathwayBrowser/#/R-RNO-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Rattus norvegicus 74986 R-RNO-1605724 https://reactome.org/PathwayBrowser/#/R-RNO-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Rattus norvegicus 74986 R-RNO-1605736 https://reactome.org/PathwayBrowser/#/R-RNO-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Rattus norvegicus 74986 R-RNO-1606312 https://reactome.org/PathwayBrowser/#/R-RNO-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Rattus norvegicus 74986 R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 74986 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 74986 R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 74986 R-RNO-9842115 https://reactome.org/PathwayBrowser/#/R-RNO-9842115 PSAP(195-273) dimer binds PE IEA Rattus norvegicus 74986 R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa 74986 R-SSC-1605632 https://reactome.org/PathwayBrowser/#/R-SSC-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Sus scrofa 74986 R-SSC-1605724 https://reactome.org/PathwayBrowser/#/R-SSC-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Sus scrofa 74986 R-SSC-1605736 https://reactome.org/PathwayBrowser/#/R-SSC-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Sus scrofa 74986 R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa 74986 R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 74986 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 74986 R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 74986 R-SSC-9842115 https://reactome.org/PathwayBrowser/#/R-SSC-9842115 PSAP(195-273) dimer binds PE IEA Sus scrofa 75048 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 75127 R-BTA-4084984 https://reactome.org/PathwayBrowser/#/R-BTA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Bos taurus 75127 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 75127 R-BTA-4084999 https://reactome.org/PathwayBrowser/#/R-BTA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 75127 R-BTA-4085029 https://reactome.org/PathwayBrowser/#/R-BTA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 75127 R-BTA-9638120 https://reactome.org/PathwayBrowser/#/R-BTA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 75127 R-CFA-4084984 https://reactome.org/PathwayBrowser/#/R-CFA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Canis familiaris 75127 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 75127 R-CFA-4084999 https://reactome.org/PathwayBrowser/#/R-CFA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 75127 R-CFA-4085029 https://reactome.org/PathwayBrowser/#/R-CFA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 75127 R-CFA-9638120 https://reactome.org/PathwayBrowser/#/R-CFA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 75127 R-DRE-4084984 https://reactome.org/PathwayBrowser/#/R-DRE-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Danio rerio 75127 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 75127 R-DRE-4085029 https://reactome.org/PathwayBrowser/#/R-DRE-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 75127 R-GGA-4084984 https://reactome.org/PathwayBrowser/#/R-GGA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Gallus gallus 75127 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 75127 R-GGA-4085029 https://reactome.org/PathwayBrowser/#/R-GGA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 75127 R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus 75127 R-HSA-4084984 https://reactome.org/PathwayBrowser/#/R-HSA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) TAS Homo sapiens 75127 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 75127 R-HSA-4084999 https://reactome.org/PathwayBrowser/#/R-HSA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 75127 R-HSA-4085029 https://reactome.org/PathwayBrowser/#/R-HSA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 75127 R-HSA-4088205 https://reactome.org/PathwayBrowser/#/R-HSA-4088205 Plasma membrane glycoconjugates translocate to the cytosol TAS Homo sapiens 75127 R-HSA-4088207 https://reactome.org/PathwayBrowser/#/R-HSA-4088207 Golgi lumen glycoconjugates translocate to the plasma membrane TAS Homo sapiens 75127 R-HSA-4088210 https://reactome.org/PathwayBrowser/#/R-HSA-4088210 Cytosolic glycoconjugates translocate to the lysosome TAS Homo sapiens 75127 R-HSA-4341669 https://reactome.org/PathwayBrowser/#/R-HSA-4341669 Defective NEU1 does not hydrolyse Neu5Ac from glycoconjugates TAS Homo sapiens 75127 R-HSA-9638120 https://reactome.org/PathwayBrowser/#/R-HSA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 75127 R-MMU-4084984 https://reactome.org/PathwayBrowser/#/R-MMU-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Mus musculus 75127 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 75127 R-MMU-4084999 https://reactome.org/PathwayBrowser/#/R-MMU-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 75127 R-MMU-4085029 https://reactome.org/PathwayBrowser/#/R-MMU-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 75127 R-MMU-9638120 https://reactome.org/PathwayBrowser/#/R-MMU-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 75127 R-RNO-4084984 https://reactome.org/PathwayBrowser/#/R-RNO-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Rattus norvegicus 75127 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 75127 R-RNO-4084999 https://reactome.org/PathwayBrowser/#/R-RNO-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 75127 R-RNO-4085029 https://reactome.org/PathwayBrowser/#/R-RNO-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 75127 R-RNO-9638120 https://reactome.org/PathwayBrowser/#/R-RNO-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 75127 R-SSC-4084984 https://reactome.org/PathwayBrowser/#/R-SSC-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Sus scrofa 75127 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 75127 R-SSC-4084999 https://reactome.org/PathwayBrowser/#/R-SSC-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 75127 R-SSC-4085029 https://reactome.org/PathwayBrowser/#/R-SSC-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 75127 R-SSC-9638120 https://reactome.org/PathwayBrowser/#/R-SSC-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 75127 R-XTR-4084984 https://reactome.org/PathwayBrowser/#/R-XTR-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Xenopus tropicalis 75127 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75127 R-XTR-4084999 https://reactome.org/PathwayBrowser/#/R-XTR-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75127 R-XTR-4085029 https://reactome.org/PathwayBrowser/#/R-XTR-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75127 R-XTR-9638120 https://reactome.org/PathwayBrowser/#/R-XTR-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75129 R-BTA-4084999 https://reactome.org/PathwayBrowser/#/R-BTA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 75129 R-BTA-4085029 https://reactome.org/PathwayBrowser/#/R-BTA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 75129 R-BTA-4085033 https://reactome.org/PathwayBrowser/#/R-BTA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Bos taurus 75129 R-BTA-9638120 https://reactome.org/PathwayBrowser/#/R-BTA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 75129 R-CFA-4084999 https://reactome.org/PathwayBrowser/#/R-CFA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 75129 R-CFA-4085029 https://reactome.org/PathwayBrowser/#/R-CFA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 75129 R-CFA-4085033 https://reactome.org/PathwayBrowser/#/R-CFA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Canis familiaris 75129 R-CFA-9638120 https://reactome.org/PathwayBrowser/#/R-CFA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 75129 R-DME-4085033 https://reactome.org/PathwayBrowser/#/R-DME-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Drosophila melanogaster 75129 R-DRE-4085029 https://reactome.org/PathwayBrowser/#/R-DRE-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 75129 R-DRE-4085033 https://reactome.org/PathwayBrowser/#/R-DRE-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Danio rerio 75129 R-GGA-4085029 https://reactome.org/PathwayBrowser/#/R-GGA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 75129 R-GGA-4085033 https://reactome.org/PathwayBrowser/#/R-GGA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Gallus gallus 75129 R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus 75129 R-HSA-4084999 https://reactome.org/PathwayBrowser/#/R-HSA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 75129 R-HSA-4085029 https://reactome.org/PathwayBrowser/#/R-HSA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 75129 R-HSA-4085033 https://reactome.org/PathwayBrowser/#/R-HSA-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) TAS Homo sapiens 75129 R-HSA-4088205 https://reactome.org/PathwayBrowser/#/R-HSA-4088205 Plasma membrane glycoconjugates translocate to the cytosol TAS Homo sapiens 75129 R-HSA-4088207 https://reactome.org/PathwayBrowser/#/R-HSA-4088207 Golgi lumen glycoconjugates translocate to the plasma membrane TAS Homo sapiens 75129 R-HSA-4088210 https://reactome.org/PathwayBrowser/#/R-HSA-4088210 Cytosolic glycoconjugates translocate to the lysosome TAS Homo sapiens 75129 R-HSA-4341669 https://reactome.org/PathwayBrowser/#/R-HSA-4341669 Defective NEU1 does not hydrolyse Neu5Ac from glycoconjugates TAS Homo sapiens 75129 R-HSA-9638120 https://reactome.org/PathwayBrowser/#/R-HSA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 75129 R-MMU-4084999 https://reactome.org/PathwayBrowser/#/R-MMU-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 75129 R-MMU-4085029 https://reactome.org/PathwayBrowser/#/R-MMU-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 75129 R-MMU-4085033 https://reactome.org/PathwayBrowser/#/R-MMU-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Mus musculus 75129 R-MMU-9638120 https://reactome.org/PathwayBrowser/#/R-MMU-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 75129 R-RNO-4084999 https://reactome.org/PathwayBrowser/#/R-RNO-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 75129 R-RNO-4085029 https://reactome.org/PathwayBrowser/#/R-RNO-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 75129 R-RNO-4085033 https://reactome.org/PathwayBrowser/#/R-RNO-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Rattus norvegicus 75129 R-RNO-9638120 https://reactome.org/PathwayBrowser/#/R-RNO-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 75129 R-SSC-4084999 https://reactome.org/PathwayBrowser/#/R-SSC-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 75129 R-SSC-4085029 https://reactome.org/PathwayBrowser/#/R-SSC-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 75129 R-SSC-4085033 https://reactome.org/PathwayBrowser/#/R-SSC-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Sus scrofa 75129 R-SSC-9638120 https://reactome.org/PathwayBrowser/#/R-SSC-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 75129 R-XTR-4084999 https://reactome.org/PathwayBrowser/#/R-XTR-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75129 R-XTR-4085029 https://reactome.org/PathwayBrowser/#/R-XTR-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75129 R-XTR-4085033 https://reactome.org/PathwayBrowser/#/R-XTR-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Xenopus tropicalis 75129 R-XTR-9638120 https://reactome.org/PathwayBrowser/#/R-XTR-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75130 R-BTA-4084978 https://reactome.org/PathwayBrowser/#/R-BTA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Bos taurus 75130 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 75130 R-BTA-4084999 https://reactome.org/PathwayBrowser/#/R-BTA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 75130 R-BTA-4085029 https://reactome.org/PathwayBrowser/#/R-BTA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 75130 R-BTA-9638120 https://reactome.org/PathwayBrowser/#/R-BTA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 75130 R-CFA-4084978 https://reactome.org/PathwayBrowser/#/R-CFA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Canis familiaris 75130 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 75130 R-CFA-4084999 https://reactome.org/PathwayBrowser/#/R-CFA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 75130 R-CFA-4085029 https://reactome.org/PathwayBrowser/#/R-CFA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 75130 R-CFA-9638120 https://reactome.org/PathwayBrowser/#/R-CFA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 75130 R-DRE-4084978 https://reactome.org/PathwayBrowser/#/R-DRE-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Danio rerio 75130 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 75130 R-DRE-4085029 https://reactome.org/PathwayBrowser/#/R-DRE-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 75130 R-GGA-4084978 https://reactome.org/PathwayBrowser/#/R-GGA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Gallus gallus 75130 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 75130 R-GGA-4085029 https://reactome.org/PathwayBrowser/#/R-GGA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 75130 R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus 75130 R-HSA-4084978 https://reactome.org/PathwayBrowser/#/R-HSA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues TAS Homo sapiens 75130 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 75130 R-HSA-4084999 https://reactome.org/PathwayBrowser/#/R-HSA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 75130 R-HSA-4085029 https://reactome.org/PathwayBrowser/#/R-HSA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 75130 R-HSA-4088205 https://reactome.org/PathwayBrowser/#/R-HSA-4088205 Plasma membrane glycoconjugates translocate to the cytosol TAS Homo sapiens 75130 R-HSA-4088207 https://reactome.org/PathwayBrowser/#/R-HSA-4088207 Golgi lumen glycoconjugates translocate to the plasma membrane TAS Homo sapiens 75130 R-HSA-4088210 https://reactome.org/PathwayBrowser/#/R-HSA-4088210 Cytosolic glycoconjugates translocate to the lysosome TAS Homo sapiens 75130 R-HSA-4341669 https://reactome.org/PathwayBrowser/#/R-HSA-4341669 Defective NEU1 does not hydrolyse Neu5Ac from glycoconjugates TAS Homo sapiens 75130 R-HSA-9638120 https://reactome.org/PathwayBrowser/#/R-HSA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 75130 R-MMU-4084978 https://reactome.org/PathwayBrowser/#/R-MMU-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Mus musculus 75130 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 75130 R-MMU-4084999 https://reactome.org/PathwayBrowser/#/R-MMU-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 75130 R-MMU-4085029 https://reactome.org/PathwayBrowser/#/R-MMU-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 75130 R-MMU-9638120 https://reactome.org/PathwayBrowser/#/R-MMU-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 75130 R-RNO-4084978 https://reactome.org/PathwayBrowser/#/R-RNO-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Rattus norvegicus 75130 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 75130 R-RNO-4084999 https://reactome.org/PathwayBrowser/#/R-RNO-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 75130 R-RNO-4085029 https://reactome.org/PathwayBrowser/#/R-RNO-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 75130 R-RNO-9638120 https://reactome.org/PathwayBrowser/#/R-RNO-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 75130 R-SSC-4084978 https://reactome.org/PathwayBrowser/#/R-SSC-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Sus scrofa 75130 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 75130 R-SSC-4084999 https://reactome.org/PathwayBrowser/#/R-SSC-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 75130 R-SSC-4085029 https://reactome.org/PathwayBrowser/#/R-SSC-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 75130 R-SSC-9638120 https://reactome.org/PathwayBrowser/#/R-SSC-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 75130 R-XTR-4084978 https://reactome.org/PathwayBrowser/#/R-XTR-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Xenopus tropicalis 75130 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75130 R-XTR-4084999 https://reactome.org/PathwayBrowser/#/R-XTR-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75130 R-XTR-4085029 https://reactome.org/PathwayBrowser/#/R-XTR-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75130 R-XTR-9638120 https://reactome.org/PathwayBrowser/#/R-XTR-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75133 R-BTA-4084978 https://reactome.org/PathwayBrowser/#/R-BTA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Bos taurus 75133 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 75133 R-BTA-4084999 https://reactome.org/PathwayBrowser/#/R-BTA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 75133 R-BTA-4085029 https://reactome.org/PathwayBrowser/#/R-BTA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 75133 R-BTA-9638120 https://reactome.org/PathwayBrowser/#/R-BTA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 75133 R-CFA-4084978 https://reactome.org/PathwayBrowser/#/R-CFA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Canis familiaris 75133 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 75133 R-CFA-4084999 https://reactome.org/PathwayBrowser/#/R-CFA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 75133 R-CFA-4085029 https://reactome.org/PathwayBrowser/#/R-CFA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 75133 R-CFA-9638120 https://reactome.org/PathwayBrowser/#/R-CFA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 75133 R-DRE-4084978 https://reactome.org/PathwayBrowser/#/R-DRE-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Danio rerio 75133 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 75133 R-DRE-4085029 https://reactome.org/PathwayBrowser/#/R-DRE-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 75133 R-GGA-4084978 https://reactome.org/PathwayBrowser/#/R-GGA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Gallus gallus 75133 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 75133 R-GGA-4085029 https://reactome.org/PathwayBrowser/#/R-GGA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 75133 R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus 75133 R-HSA-4084978 https://reactome.org/PathwayBrowser/#/R-HSA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues TAS Homo sapiens 75133 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 75133 R-HSA-4084999 https://reactome.org/PathwayBrowser/#/R-HSA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 75133 R-HSA-4085029 https://reactome.org/PathwayBrowser/#/R-HSA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 75133 R-HSA-9638120 https://reactome.org/PathwayBrowser/#/R-HSA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 75133 R-MMU-4084978 https://reactome.org/PathwayBrowser/#/R-MMU-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Mus musculus 75133 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 75133 R-MMU-4084999 https://reactome.org/PathwayBrowser/#/R-MMU-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 75133 R-MMU-4085029 https://reactome.org/PathwayBrowser/#/R-MMU-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 75133 R-MMU-9638120 https://reactome.org/PathwayBrowser/#/R-MMU-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 75133 R-RNO-4084978 https://reactome.org/PathwayBrowser/#/R-RNO-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Rattus norvegicus 75133 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 75133 R-RNO-4084999 https://reactome.org/PathwayBrowser/#/R-RNO-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 75133 R-RNO-4085029 https://reactome.org/PathwayBrowser/#/R-RNO-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 75133 R-RNO-9638120 https://reactome.org/PathwayBrowser/#/R-RNO-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 75133 R-SSC-4084978 https://reactome.org/PathwayBrowser/#/R-SSC-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Sus scrofa 75133 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 75133 R-SSC-4084999 https://reactome.org/PathwayBrowser/#/R-SSC-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 75133 R-SSC-4085029 https://reactome.org/PathwayBrowser/#/R-SSC-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 75133 R-SSC-9638120 https://reactome.org/PathwayBrowser/#/R-SSC-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 75133 R-XTR-4084978 https://reactome.org/PathwayBrowser/#/R-XTR-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Xenopus tropicalis 75133 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75133 R-XTR-4084999 https://reactome.org/PathwayBrowser/#/R-XTR-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75133 R-XTR-4085029 https://reactome.org/PathwayBrowser/#/R-XTR-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75133 R-XTR-9638120 https://reactome.org/PathwayBrowser/#/R-XTR-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 75137 R-BTA-1482759 https://reactome.org/PathwayBrowser/#/R-BTA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Bos taurus 75137 R-BTA-1482867 https://reactome.org/PathwayBrowser/#/R-BTA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Bos taurus 75137 R-CEL-1482867 https://reactome.org/PathwayBrowser/#/R-CEL-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Caenorhabditis elegans 75137 R-CFA-1482759 https://reactome.org/PathwayBrowser/#/R-CFA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Canis familiaris 75137 R-CFA-1482867 https://reactome.org/PathwayBrowser/#/R-CFA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Canis familiaris 75137 R-DDI-1482867 https://reactome.org/PathwayBrowser/#/R-DDI-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Dictyostelium discoideum 75137 R-DRE-1482759 https://reactome.org/PathwayBrowser/#/R-DRE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Danio rerio 75137 R-DRE-1482867 https://reactome.org/PathwayBrowser/#/R-DRE-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Danio rerio 75137 R-GGA-1482759 https://reactome.org/PathwayBrowser/#/R-GGA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Gallus gallus 75137 R-GGA-1482867 https://reactome.org/PathwayBrowser/#/R-GGA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Gallus gallus 75137 R-HSA-1482759 https://reactome.org/PathwayBrowser/#/R-HSA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) TAS Homo sapiens 75137 R-HSA-1482860 https://reactome.org/PathwayBrowser/#/R-HSA-1482860 DLCL transports from the IM to the ER TAS Homo sapiens 75137 R-HSA-1482867 https://reactome.org/PathwayBrowser/#/R-HSA-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) TAS Homo sapiens 75137 R-MMU-1482759 https://reactome.org/PathwayBrowser/#/R-MMU-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Mus musculus 75137 R-MMU-1482867 https://reactome.org/PathwayBrowser/#/R-MMU-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Mus musculus 75137 R-RNO-1482759 https://reactome.org/PathwayBrowser/#/R-RNO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Rattus norvegicus 75137 R-RNO-1482867 https://reactome.org/PathwayBrowser/#/R-RNO-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Rattus norvegicus 75137 R-SCE-1482759 https://reactome.org/PathwayBrowser/#/R-SCE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Saccharomyces cerevisiae 75137 R-SCE-1482867 https://reactome.org/PathwayBrowser/#/R-SCE-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Saccharomyces cerevisiae 75137 R-SPO-1482759 https://reactome.org/PathwayBrowser/#/R-SPO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Schizosaccharomyces pombe 75137 R-SPO-1482867 https://reactome.org/PathwayBrowser/#/R-SPO-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Schizosaccharomyces pombe 75137 R-SSC-1482759 https://reactome.org/PathwayBrowser/#/R-SSC-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Sus scrofa 75137 R-SSC-1482867 https://reactome.org/PathwayBrowser/#/R-SSC-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Sus scrofa 75137 R-XTR-1482759 https://reactome.org/PathwayBrowser/#/R-XTR-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Xenopus tropicalis 75137 R-XTR-1482867 https://reactome.org/PathwayBrowser/#/R-XTR-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Xenopus tropicalis 7514 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 7514 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 7514 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 7514 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 7514 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 7514 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 7514 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 7514 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 7514 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 7514 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 7514 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 7514 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 7514 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 7514 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 7514 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 7550 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 7550 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 7550 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 7550 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 7550 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 7550 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 7550 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 7550 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 7550 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 7550 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 75562 R-BTA-8878654 https://reactome.org/PathwayBrowser/#/R-BTA-8878654 ACP6 hydrolyses MYS-LPA IEA Bos taurus 75562 R-CEL-8878654 https://reactome.org/PathwayBrowser/#/R-CEL-8878654 ACP6 hydrolyses MYS-LPA IEA Caenorhabditis elegans 75562 R-CFA-8878654 https://reactome.org/PathwayBrowser/#/R-CFA-8878654 ACP6 hydrolyses MYS-LPA IEA Canis familiaris 75562 R-DDI-8878654 https://reactome.org/PathwayBrowser/#/R-DDI-8878654 ACP6 hydrolyses MYS-LPA IEA Dictyostelium discoideum 75562 R-DRE-8878654 https://reactome.org/PathwayBrowser/#/R-DRE-8878654 ACP6 hydrolyses MYS-LPA IEA Danio rerio 75562 R-GGA-8878654 https://reactome.org/PathwayBrowser/#/R-GGA-8878654 ACP6 hydrolyses MYS-LPA IEA Gallus gallus 75562 R-HSA-8878654 https://reactome.org/PathwayBrowser/#/R-HSA-8878654 ACP6 hydrolyses MYS-LPA TAS Homo sapiens 75562 R-MMU-8878654 https://reactome.org/PathwayBrowser/#/R-MMU-8878654 ACP6 hydrolyses MYS-LPA IEA Mus musculus 75562 R-RNO-8878654 https://reactome.org/PathwayBrowser/#/R-RNO-8878654 ACP6 hydrolyses MYS-LPA IEA Rattus norvegicus 75562 R-SPO-8878654 https://reactome.org/PathwayBrowser/#/R-SPO-8878654 ACP6 hydrolyses MYS-LPA IEA Schizosaccharomyces pombe 75562 R-SSC-8878654 https://reactome.org/PathwayBrowser/#/R-SSC-8878654 ACP6 hydrolyses MYS-LPA IEA Sus scrofa 75562 R-XTR-8878654 https://reactome.org/PathwayBrowser/#/R-XTR-8878654 ACP6 hydrolyses MYS-LPA IEA Xenopus tropicalis 75571 R-BTA-5694462 https://reactome.org/PathwayBrowser/#/R-BTA-5694462 ABHD6,12 hydrolyse 3AG IEA Bos taurus 75571 R-CEL-5694462 https://reactome.org/PathwayBrowser/#/R-CEL-5694462 ABHD6,12 hydrolyse 3AG IEA Caenorhabditis elegans 75571 R-CFA-5694462 https://reactome.org/PathwayBrowser/#/R-CFA-5694462 ABHD6,12 hydrolyse 3AG IEA Canis familiaris 75571 R-DME-5694462 https://reactome.org/PathwayBrowser/#/R-DME-5694462 ABHD6,12 hydrolyse 3AG IEA Drosophila melanogaster 75571 R-DRE-5694462 https://reactome.org/PathwayBrowser/#/R-DRE-5694462 ABHD6,12 hydrolyse 3AG IEA Danio rerio 75571 R-GGA-5694462 https://reactome.org/PathwayBrowser/#/R-GGA-5694462 ABHD6,12 hydrolyse 3AG IEA Gallus gallus 75571 R-HSA-5694462 https://reactome.org/PathwayBrowser/#/R-HSA-5694462 ABHD6,12 hydrolyse 3AG TAS Homo sapiens 75571 R-MMU-5694462 https://reactome.org/PathwayBrowser/#/R-MMU-5694462 ABHD6,12 hydrolyse 3AG IEA Mus musculus 75571 R-RNO-5694462 https://reactome.org/PathwayBrowser/#/R-RNO-5694462 ABHD6,12 hydrolyse 3AG IEA Rattus norvegicus 75571 R-SCE-5694462 https://reactome.org/PathwayBrowser/#/R-SCE-5694462 ABHD6,12 hydrolyse 3AG IEA Saccharomyces cerevisiae 75571 R-SSC-5694462 https://reactome.org/PathwayBrowser/#/R-SSC-5694462 ABHD6,12 hydrolyse 3AG IEA Sus scrofa 75571 R-XTR-5694462 https://reactome.org/PathwayBrowser/#/R-XTR-5694462 ABHD6,12 hydrolyse 3AG IEA Xenopus tropicalis 75584 R-BTA-8848582 https://reactome.org/PathwayBrowser/#/R-BTA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Bos taurus 75584 R-CEL-8848582 https://reactome.org/PathwayBrowser/#/R-CEL-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Caenorhabditis elegans 75584 R-CFA-8848582 https://reactome.org/PathwayBrowser/#/R-CFA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Canis familiaris 75584 R-DDI-8848582 https://reactome.org/PathwayBrowser/#/R-DDI-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Dictyostelium discoideum 75584 R-DME-8848582 https://reactome.org/PathwayBrowser/#/R-DME-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Drosophila melanogaster 75584 R-DRE-8848582 https://reactome.org/PathwayBrowser/#/R-DRE-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Danio rerio 75584 R-GGA-8848582 https://reactome.org/PathwayBrowser/#/R-GGA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Gallus gallus 75584 R-HSA-8848582 https://reactome.org/PathwayBrowser/#/R-HSA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester TAS Homo sapiens 75584 R-MMU-8848582 https://reactome.org/PathwayBrowser/#/R-MMU-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Mus musculus 75584 R-RNO-8848582 https://reactome.org/PathwayBrowser/#/R-RNO-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Rattus norvegicus 75584 R-SCE-8848582 https://reactome.org/PathwayBrowser/#/R-SCE-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Saccharomyces cerevisiae 75584 R-SPO-8848582 https://reactome.org/PathwayBrowser/#/R-SPO-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Schizosaccharomyces pombe 75584 R-SSC-8848582 https://reactome.org/PathwayBrowser/#/R-SSC-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Sus scrofa 75584 R-XTR-8848582 https://reactome.org/PathwayBrowser/#/R-XTR-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester IEA Xenopus tropicalis 75627 R-BTA-5696424 https://reactome.org/PathwayBrowser/#/R-BTA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Bos taurus 75627 R-CEL-5696424 https://reactome.org/PathwayBrowser/#/R-CEL-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Caenorhabditis elegans 75627 R-CFA-5696424 https://reactome.org/PathwayBrowser/#/R-CFA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Canis familiaris 75627 R-DDI-5696424 https://reactome.org/PathwayBrowser/#/R-DDI-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Dictyostelium discoideum 75627 R-DME-5696424 https://reactome.org/PathwayBrowser/#/R-DME-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Drosophila melanogaster 75627 R-DRE-5696424 https://reactome.org/PathwayBrowser/#/R-DRE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Danio rerio 75627 R-GGA-5696424 https://reactome.org/PathwayBrowser/#/R-GGA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Gallus gallus 75627 R-HSA-5696424 https://reactome.org/PathwayBrowser/#/R-HSA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters TAS Homo sapiens 75627 R-MMU-5696424 https://reactome.org/PathwayBrowser/#/R-MMU-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Mus musculus 75627 R-RNO-5696424 https://reactome.org/PathwayBrowser/#/R-RNO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Rattus norvegicus 75627 R-SCE-5696424 https://reactome.org/PathwayBrowser/#/R-SCE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Saccharomyces cerevisiae 75627 R-SPO-5696424 https://reactome.org/PathwayBrowser/#/R-SPO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Schizosaccharomyces pombe 75627 R-XTR-5696424 https://reactome.org/PathwayBrowser/#/R-XTR-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Xenopus tropicalis 7565 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 7565 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 7565 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 7565 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 7565 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 7565 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 7565 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 7565 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 7565 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 7565 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 7575 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 7575 R-BTA-9725855 https://reactome.org/PathwayBrowser/#/R-BTA-9725855 NR3C2 binds NR3C2 antagonists IEA Bos taurus 7575 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 7575 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 7575 R-CFA-9725855 https://reactome.org/PathwayBrowser/#/R-CFA-9725855 NR3C2 binds NR3C2 antagonists IEA Canis familiaris 7575 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 7575 R-DME-9725855 https://reactome.org/PathwayBrowser/#/R-DME-9725855 NR3C2 binds NR3C2 antagonists IEA Drosophila melanogaster 7575 R-DRE-9725855 https://reactome.org/PathwayBrowser/#/R-DRE-9725855 NR3C2 binds NR3C2 antagonists IEA Danio rerio 7575 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 7575 R-GGA-9725855 https://reactome.org/PathwayBrowser/#/R-GGA-9725855 NR3C2 binds NR3C2 antagonists IEA Gallus gallus 7575 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 7575 R-HSA-9725855 https://reactome.org/PathwayBrowser/#/R-HSA-9725855 NR3C2 binds NR3C2 antagonists TAS Homo sapiens 7575 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 7575 R-MMU-9725855 https://reactome.org/PathwayBrowser/#/R-MMU-9725855 NR3C2 binds NR3C2 antagonists IEA Mus musculus 7575 R-PFA-9725855 https://reactome.org/PathwayBrowser/#/R-PFA-9725855 NR3C2 binds NR3C2 antagonists IEA Plasmodium falciparum 7575 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 7575 R-RNO-9725855 https://reactome.org/PathwayBrowser/#/R-RNO-9725855 NR3C2 binds NR3C2 antagonists IEA Rattus norvegicus 7575 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 7575 R-SSC-9725855 https://reactome.org/PathwayBrowser/#/R-SSC-9725855 NR3C2 binds NR3C2 antagonists IEA Sus scrofa 7575 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 7575 R-XTR-9725855 https://reactome.org/PathwayBrowser/#/R-XTR-9725855 NR3C2 binds NR3C2 antagonists IEA Xenopus tropicalis 7577 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 7577 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 7577 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 7577 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 7577 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 7577 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 7577 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 7577 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 7577 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 7577 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 7582 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 7582 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 7582 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 7582 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 7582 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 7582 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 7582 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 7582 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 7582 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 7582 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 75991 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 75991 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 75991 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus 75991 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 75991 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 75991 R-CEL-9657599 https://reactome.org/PathwayBrowser/#/R-CEL-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Caenorhabditis elegans 75991 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 75991 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 75991 R-CFA-9657599 https://reactome.org/PathwayBrowser/#/R-CFA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Canis familiaris 75991 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 75991 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 75991 R-DME-9657599 https://reactome.org/PathwayBrowser/#/R-DME-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Drosophila melanogaster 75991 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 75991 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 75991 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus 75991 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 75991 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 75991 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 75991 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 75991 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 75991 R-MMU-9657599 https://reactome.org/PathwayBrowser/#/R-MMU-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Mus musculus 75991 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 75991 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 75991 R-RNO-9657599 https://reactome.org/PathwayBrowser/#/R-RNO-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Rattus norvegicus 75991 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 75991 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 75991 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa 75998 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 75998 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 75998 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus 75998 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 75998 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 75998 R-CEL-9657599 https://reactome.org/PathwayBrowser/#/R-CEL-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Caenorhabditis elegans 75998 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 75998 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 75998 R-CFA-9657599 https://reactome.org/PathwayBrowser/#/R-CFA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Canis familiaris 75998 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 75998 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 75998 R-DME-9657599 https://reactome.org/PathwayBrowser/#/R-DME-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Drosophila melanogaster 75998 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 75998 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 75998 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus 75998 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 75998 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 75998 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 75998 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 75998 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 75998 R-MMU-9657599 https://reactome.org/PathwayBrowser/#/R-MMU-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Mus musculus 75998 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 75998 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 75998 R-RNO-9657599 https://reactome.org/PathwayBrowser/#/R-RNO-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Rattus norvegicus 75998 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 75998 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 75998 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa 76018 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 76018 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 76018 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 76018 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 76018 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 76018 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 76018 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 76018 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 76018 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 76018 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 76072 R-BTA-2685505 https://reactome.org/PathwayBrowser/#/R-BTA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Bos taurus 76072 R-CFA-2685505 https://reactome.org/PathwayBrowser/#/R-CFA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Canis familiaris 76072 R-DRE-2685505 https://reactome.org/PathwayBrowser/#/R-DRE-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Danio rerio 76072 R-GGA-2685505 https://reactome.org/PathwayBrowser/#/R-GGA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Gallus gallus 76072 R-HSA-2685505 https://reactome.org/PathwayBrowser/#/R-HSA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol TAS Homo sapiens 76072 R-MMU-2685505 https://reactome.org/PathwayBrowser/#/R-MMU-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Mus musculus 76072 R-RNO-2685505 https://reactome.org/PathwayBrowser/#/R-RNO-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Rattus norvegicus 76072 R-SSC-2685505 https://reactome.org/PathwayBrowser/#/R-SSC-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Sus scrofa 76072 R-XTR-2685505 https://reactome.org/PathwayBrowser/#/R-XTR-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Xenopus tropicalis 76177 R-BTA-5693761 https://reactome.org/PathwayBrowser/#/R-BTA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Bos taurus 76177 R-CEL-5693761 https://reactome.org/PathwayBrowser/#/R-CEL-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Caenorhabditis elegans 76177 R-CFA-5693761 https://reactome.org/PathwayBrowser/#/R-CFA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Canis familiaris 76177 R-DDI-5693761 https://reactome.org/PathwayBrowser/#/R-DDI-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Dictyostelium discoideum 76177 R-DME-5693761 https://reactome.org/PathwayBrowser/#/R-DME-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Drosophila melanogaster 76177 R-GGA-5693761 https://reactome.org/PathwayBrowser/#/R-GGA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Gallus gallus 76177 R-HSA-5693761 https://reactome.org/PathwayBrowser/#/R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids TAS Homo sapiens 76177 R-MMU-5693761 https://reactome.org/PathwayBrowser/#/R-MMU-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Mus musculus 76177 R-RNO-5693761 https://reactome.org/PathwayBrowser/#/R-RNO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Rattus norvegicus 76177 R-SCE-5693761 https://reactome.org/PathwayBrowser/#/R-SCE-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Saccharomyces cerevisiae 76177 R-SPO-5693761 https://reactome.org/PathwayBrowser/#/R-SPO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Schizosaccharomyces pombe 76177 R-SSC-5693761 https://reactome.org/PathwayBrowser/#/R-SSC-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Sus scrofa 76177 R-XTR-5693761 https://reactome.org/PathwayBrowser/#/R-XTR-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Xenopus tropicalis 76279 R-BTA-3371467 https://reactome.org/PathwayBrowser/#/R-BTA-3371467 SIRT1 deacetylates HSF1 IEA Bos taurus 76279 R-BTA-427514 https://reactome.org/PathwayBrowser/#/R-BTA-427514 eNoSC deacetylates histone H3 IEA Bos taurus 76279 R-BTA-5685953 https://reactome.org/PathwayBrowser/#/R-BTA-5685953 SIRT6 deacetylates RBBP8 IEA Bos taurus 76279 R-BTA-5688294 https://reactome.org/PathwayBrowser/#/R-BTA-5688294 SIRT5 deacetylates Cytochrome C IEA Bos taurus 76279 R-BTA-9620532 https://reactome.org/PathwayBrowser/#/R-BTA-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Bos taurus 76279 R-BTA-9667952 https://reactome.org/PathwayBrowser/#/R-BTA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Bos taurus 76279 R-CEL-5685953 https://reactome.org/PathwayBrowser/#/R-CEL-5685953 SIRT6 deacetylates RBBP8 IEA Caenorhabditis elegans 76279 R-CEL-9620532 https://reactome.org/PathwayBrowser/#/R-CEL-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Caenorhabditis elegans 76279 R-CFA-3371467 https://reactome.org/PathwayBrowser/#/R-CFA-3371467 SIRT1 deacetylates HSF1 IEA Canis familiaris 76279 R-CFA-427514 https://reactome.org/PathwayBrowser/#/R-CFA-427514 eNoSC deacetylates histone H3 IEA Canis familiaris 76279 R-CFA-5685953 https://reactome.org/PathwayBrowser/#/R-CFA-5685953 SIRT6 deacetylates RBBP8 IEA Canis familiaris 76279 R-CFA-9620532 https://reactome.org/PathwayBrowser/#/R-CFA-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Canis familiaris 76279 R-CFA-9667952 https://reactome.org/PathwayBrowser/#/R-CFA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Canis familiaris 76279 R-DDI-427514 https://reactome.org/PathwayBrowser/#/R-DDI-427514 eNoSC deacetylates histone H3 IEA Dictyostelium discoideum 76279 R-DDI-5688294 https://reactome.org/PathwayBrowser/#/R-DDI-5688294 SIRT5 deacetylates Cytochrome C IEA Dictyostelium discoideum 76279 R-DME-427514 https://reactome.org/PathwayBrowser/#/R-DME-427514 eNoSC deacetylates histone H3 IEA Drosophila melanogaster 76279 R-DME-9620532 https://reactome.org/PathwayBrowser/#/R-DME-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Drosophila melanogaster 76279 R-DME-9667952 https://reactome.org/PathwayBrowser/#/R-DME-9667952 ANKLE2 is deacetylated by SIRT2 IEA Drosophila melanogaster 76279 R-DRE-5685953 https://reactome.org/PathwayBrowser/#/R-DRE-5685953 SIRT6 deacetylates RBBP8 IEA Danio rerio 76279 R-DRE-5688294 https://reactome.org/PathwayBrowser/#/R-DRE-5688294 SIRT5 deacetylates Cytochrome C IEA Danio rerio 76279 R-DRE-9667952 https://reactome.org/PathwayBrowser/#/R-DRE-9667952 ANKLE2 is deacetylated by SIRT2 IEA Danio rerio 76279 R-GGA-3371467 https://reactome.org/PathwayBrowser/#/R-GGA-3371467 SIRT1 deacetylates HSF1 IEA Gallus gallus 76279 R-GGA-5685953 https://reactome.org/PathwayBrowser/#/R-GGA-5685953 SIRT6 deacetylates RBBP8 IEA Gallus gallus 76279 R-GGA-5688294 https://reactome.org/PathwayBrowser/#/R-GGA-5688294 SIRT5 deacetylates Cytochrome C IEA Gallus gallus 76279 R-GGA-9620532 https://reactome.org/PathwayBrowser/#/R-GGA-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Gallus gallus 76279 R-GGA-9667952 https://reactome.org/PathwayBrowser/#/R-GGA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Gallus gallus 76279 R-HSA-3371467 https://reactome.org/PathwayBrowser/#/R-HSA-3371467 SIRT1 deacetylates HSF1 TAS Homo sapiens 76279 R-HSA-427514 https://reactome.org/PathwayBrowser/#/R-HSA-427514 eNoSC deacetylates histone H3 TAS Homo sapiens 76279 R-HSA-5211239 https://reactome.org/PathwayBrowser/#/R-HSA-5211239 SIRT1 deacetylates TAF1B in SL1 complex IEA Homo sapiens 76279 R-HSA-5685953 https://reactome.org/PathwayBrowser/#/R-HSA-5685953 SIRT6 deacetylates RBBP8 TAS Homo sapiens 76279 R-HSA-5688294 https://reactome.org/PathwayBrowser/#/R-HSA-5688294 SIRT5 deacetylates Cytochrome C TAS Homo sapiens 76279 R-HSA-9604829 https://reactome.org/PathwayBrowser/#/R-HSA-9604829 SIRT6 deacetylates histones at NOTCH1 and NOTCH4 gene promoters IEA Homo sapiens 76279 R-HSA-9620532 https://reactome.org/PathwayBrowser/#/R-HSA-9620532 SIRT1,SIRT3 deacetylate FOXO3 TAS Homo sapiens 76279 R-HSA-9626962 https://reactome.org/PathwayBrowser/#/R-HSA-9626962 SIRT1 deacetylates FOXO1 IEA Homo sapiens 76279 R-HSA-9667952 https://reactome.org/PathwayBrowser/#/R-HSA-9667952 ANKLE2 is deacetylated by SIRT2 TAS Homo sapiens 76279 R-MMU-3371467 https://reactome.org/PathwayBrowser/#/R-MMU-3371467 SIRT1 deacetylates HSF1 IEA Mus musculus 76279 R-MMU-5211233 https://reactome.org/PathwayBrowser/#/R-MMU-5211233 Sirt1 deacetylates Taf1b in SL1 complex TAS Mus musculus 76279 R-MMU-5685953 https://reactome.org/PathwayBrowser/#/R-MMU-5685953 SIRT6 deacetylates RBBP8 IEA Mus musculus 76279 R-MMU-5688294 https://reactome.org/PathwayBrowser/#/R-MMU-5688294 SIRT5 deacetylates Cytochrome C IEA Mus musculus 76279 R-MMU-9604841 https://reactome.org/PathwayBrowser/#/R-MMU-9604841 Sirt6 deacetylates histones at Notch1 and Notch4 gene promoters TAS Mus musculus 76279 R-MMU-9620532 https://reactome.org/PathwayBrowser/#/R-MMU-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Mus musculus 76279 R-MMU-9626966 https://reactome.org/PathwayBrowser/#/R-MMU-9626966 Sirt1 deacetylates Foxo1 TAS Mus musculus 76279 R-MMU-9667952 https://reactome.org/PathwayBrowser/#/R-MMU-9667952 ANKLE2 is deacetylated by SIRT2 IEA Mus musculus 76279 R-PFA-5688294 https://reactome.org/PathwayBrowser/#/R-PFA-5688294 SIRT5 deacetylates Cytochrome C IEA Plasmodium falciparum 76279 R-RNO-3371467 https://reactome.org/PathwayBrowser/#/R-RNO-3371467 SIRT1 deacetylates HSF1 IEA Rattus norvegicus 76279 R-RNO-427514 https://reactome.org/PathwayBrowser/#/R-RNO-427514 eNoSC deacetylates histone H3 IEA Rattus norvegicus 76279 R-RNO-5685953 https://reactome.org/PathwayBrowser/#/R-RNO-5685953 SIRT6 deacetylates RBBP8 IEA Rattus norvegicus 76279 R-RNO-5688294 https://reactome.org/PathwayBrowser/#/R-RNO-5688294 SIRT5 deacetylates Cytochrome C IEA Rattus norvegicus 76279 R-RNO-9620532 https://reactome.org/PathwayBrowser/#/R-RNO-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Rattus norvegicus 76279 R-RNO-9667952 https://reactome.org/PathwayBrowser/#/R-RNO-9667952 ANKLE2 is deacetylated by SIRT2 IEA Rattus norvegicus 76279 R-SCE-427514 https://reactome.org/PathwayBrowser/#/R-SCE-427514 eNoSC deacetylates histone H3 IEA Saccharomyces cerevisiae 76279 R-SPO-427514 https://reactome.org/PathwayBrowser/#/R-SPO-427514 eNoSC deacetylates histone H3 IEA Schizosaccharomyces pombe 76279 R-SSC-3371467 https://reactome.org/PathwayBrowser/#/R-SSC-3371467 SIRT1 deacetylates HSF1 IEA Sus scrofa 76279 R-SSC-427514 https://reactome.org/PathwayBrowser/#/R-SSC-427514 eNoSC deacetylates histone H3 IEA Sus scrofa 76279 R-SSC-5685953 https://reactome.org/PathwayBrowser/#/R-SSC-5685953 SIRT6 deacetylates RBBP8 IEA Sus scrofa 76279 R-SSC-5688294 https://reactome.org/PathwayBrowser/#/R-SSC-5688294 SIRT5 deacetylates Cytochrome C IEA Sus scrofa 76279 R-SSC-9620532 https://reactome.org/PathwayBrowser/#/R-SSC-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Sus scrofa 76279 R-SSC-9667952 https://reactome.org/PathwayBrowser/#/R-SSC-9667952 ANKLE2 is deacetylated by SIRT2 IEA Sus scrofa 76279 R-XTR-5685953 https://reactome.org/PathwayBrowser/#/R-XTR-5685953 SIRT6 deacetylates RBBP8 IEA Xenopus tropicalis 76279 R-XTR-5688294 https://reactome.org/PathwayBrowser/#/R-XTR-5688294 SIRT5 deacetylates Cytochrome C IEA Xenopus tropicalis 76306 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 76306 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 76306 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 76306 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 76306 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 76306 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 76306 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 76306 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 76306 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 76591 R-BTA-9024326 https://reactome.org/PathwayBrowser/#/R-BTA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Bos taurus 76591 R-BTA-9024334 https://reactome.org/PathwayBrowser/#/R-BTA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Bos taurus 76591 R-BTA-9029517 https://reactome.org/PathwayBrowser/#/R-BTA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Bos taurus 76591 R-BTA-9029551 https://reactome.org/PathwayBrowser/#/R-BTA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Bos taurus 76591 R-BTA-9029561 https://reactome.org/PathwayBrowser/#/R-BTA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Bos taurus 76591 R-BTA-9029566 https://reactome.org/PathwayBrowser/#/R-BTA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Bos taurus 76591 R-BTA-9029580 https://reactome.org/PathwayBrowser/#/R-BTA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Bos taurus 76591 R-BTA-9038029 https://reactome.org/PathwayBrowser/#/R-BTA-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Bos taurus 76591 R-CFA-9024326 https://reactome.org/PathwayBrowser/#/R-CFA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Canis familiaris 76591 R-CFA-9024334 https://reactome.org/PathwayBrowser/#/R-CFA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Canis familiaris 76591 R-CFA-9029517 https://reactome.org/PathwayBrowser/#/R-CFA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Canis familiaris 76591 R-CFA-9029551 https://reactome.org/PathwayBrowser/#/R-CFA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Canis familiaris 76591 R-CFA-9029561 https://reactome.org/PathwayBrowser/#/R-CFA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Canis familiaris 76591 R-CFA-9029566 https://reactome.org/PathwayBrowser/#/R-CFA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Canis familiaris 76591 R-CFA-9029580 https://reactome.org/PathwayBrowser/#/R-CFA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Canis familiaris 76591 R-CFA-9038029 https://reactome.org/PathwayBrowser/#/R-CFA-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Canis familiaris 76591 R-DME-9024326 https://reactome.org/PathwayBrowser/#/R-DME-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Drosophila melanogaster 76591 R-DME-9024334 https://reactome.org/PathwayBrowser/#/R-DME-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Drosophila melanogaster 76591 R-DME-9029517 https://reactome.org/PathwayBrowser/#/R-DME-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Drosophila melanogaster 76591 R-DME-9029551 https://reactome.org/PathwayBrowser/#/R-DME-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Drosophila melanogaster 76591 R-DME-9029561 https://reactome.org/PathwayBrowser/#/R-DME-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Drosophila melanogaster 76591 R-DME-9029566 https://reactome.org/PathwayBrowser/#/R-DME-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Drosophila melanogaster 76591 R-DME-9029580 https://reactome.org/PathwayBrowser/#/R-DME-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Drosophila melanogaster 76591 R-DME-9038029 https://reactome.org/PathwayBrowser/#/R-DME-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Drosophila melanogaster 76591 R-DRE-9038029 https://reactome.org/PathwayBrowser/#/R-DRE-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Danio rerio 76591 R-GGA-9038029 https://reactome.org/PathwayBrowser/#/R-GGA-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Gallus gallus 76591 R-HSA-9024326 https://reactome.org/PathwayBrowser/#/R-HSA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex TAS Homo sapiens 76591 R-HSA-9024334 https://reactome.org/PathwayBrowser/#/R-HSA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene TAS Homo sapiens 76591 R-HSA-9024361 https://reactome.org/PathwayBrowser/#/R-HSA-9024361 Expression of ABCG1 regulated by NR1H2,3 TAS Homo sapiens 76591 R-HSA-9024386 https://reactome.org/PathwayBrowser/#/R-HSA-9024386 Oxysterol-induced binding of NR1H2,3:RXR to the ABCG1 gene TAS Homo sapiens 76591 R-HSA-9028524 https://reactome.org/PathwayBrowser/#/R-HSA-9028524 NR1H3, NRIP1 bind the PCK1 gene TAS Homo sapiens 76591 R-HSA-9028525 https://reactome.org/PathwayBrowser/#/R-HSA-9028525 NR1H2 or NR1H3, NRIP1 bind the SREBF1 gene TAS Homo sapiens 76591 R-HSA-9028526 https://reactome.org/PathwayBrowser/#/R-HSA-9028526 NR1H2 or NR1H3, NRIP1 bind the SCD gene TAS Homo sapiens 76591 R-HSA-9028533 https://reactome.org/PathwayBrowser/#/R-HSA-9028533 NR1H2,3, NRIP1 bind the FASN gene TAS Homo sapiens 76591 R-HSA-9029517 https://reactome.org/PathwayBrowser/#/R-HSA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex TAS Homo sapiens 76591 R-HSA-9029521 https://reactome.org/PathwayBrowser/#/R-HSA-9029521 NR1H2,3 binds the ABCG5 gene TAS Homo sapiens 76591 R-HSA-9029531 https://reactome.org/PathwayBrowser/#/R-HSA-9029531 Expression of ABCG5 regulated by NR1H2,3 TAS Homo sapiens 76591 R-HSA-9029536 https://reactome.org/PathwayBrowser/#/R-HSA-9029536 Expression of UGT1A3 TAS Homo sapiens 76591 R-HSA-9029551 https://reactome.org/PathwayBrowser/#/R-HSA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex TAS Homo sapiens 76591 R-HSA-9029555 https://reactome.org/PathwayBrowser/#/R-HSA-9029555 NR1H2,3 binds the ABCG8 gene TAS Homo sapiens 76591 R-HSA-9029561 https://reactome.org/PathwayBrowser/#/R-HSA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter TAS Homo sapiens 76591 R-HSA-9029566 https://reactome.org/PathwayBrowser/#/R-HSA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene TAS Homo sapiens 76591 R-HSA-9029580 https://reactome.org/PathwayBrowser/#/R-HSA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex TAS Homo sapiens 76591 R-HSA-9029591 https://reactome.org/PathwayBrowser/#/R-HSA-9029591 Expression of ABCG8 regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9031510 https://reactome.org/PathwayBrowser/#/R-HSA-9031510 Expression of APOC1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9031512 https://reactome.org/PathwayBrowser/#/R-HSA-9031512 Expression of APOE regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9031518 https://reactome.org/PathwayBrowser/#/R-HSA-9031518 NR1H2,3 binds the APOC1 gene TAS Homo sapiens 76591 R-HSA-9031521 https://reactome.org/PathwayBrowser/#/R-HSA-9031521 NR1H2,3 binds the APOC2 gene TAS Homo sapiens 76591 R-HSA-9031522 https://reactome.org/PathwayBrowser/#/R-HSA-9031522 NR1H2,3 binds the APOE gene TAS Homo sapiens 76591 R-HSA-9031527 https://reactome.org/PathwayBrowser/#/R-HSA-9031527 Expression of APOC2 regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9035133 https://reactome.org/PathwayBrowser/#/R-HSA-9035133 NR1H2,3 binds the CETP gene TAS Homo sapiens 76591 R-HSA-9035143 https://reactome.org/PathwayBrowser/#/R-HSA-9035143 NR1H2,3 binds the APOC4 gene TAS Homo sapiens 76591 R-HSA-9035167 https://reactome.org/PathwayBrowser/#/R-HSA-9035167 NR1H2,3 binds the EEPD1 gene TAS Homo sapiens 76591 R-HSA-9035169 https://reactome.org/PathwayBrowser/#/R-HSA-9035169 Expression of CETP regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9035180 https://reactome.org/PathwayBrowser/#/R-HSA-9035180 Expression of EEPD1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9035185 https://reactome.org/PathwayBrowser/#/R-HSA-9035185 NR1H2,3 binds the NR1H3 gene TAS Homo sapiens 76591 R-HSA-9035279 https://reactome.org/PathwayBrowser/#/R-HSA-9035279 Expression of APOC4 regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9035281 https://reactome.org/PathwayBrowser/#/R-HSA-9035281 NR1H3 gene transcription regulated by NR1H2,3 TAS Homo sapiens 76591 R-HSA-9038029 https://reactome.org/PathwayBrowser/#/R-HSA-9038029 27-hydroxysterol binds ESR1, ESR2 TAS Homo sapiens 76591 R-HSA-9605051 https://reactome.org/PathwayBrowser/#/R-HSA-9605051 Expression of PCK1 regulated by NR1H3 TAS Homo sapiens 76591 R-HSA-9605056 https://reactome.org/PathwayBrowser/#/R-HSA-9605056 Expression of SREBF1 (SREBP1) regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9605057 https://reactome.org/PathwayBrowser/#/R-HSA-9605057 ABCA1 gene transcription regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9605060 https://reactome.org/PathwayBrowser/#/R-HSA-9605060 Expression of SCD regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9605063 https://reactome.org/PathwayBrowser/#/R-HSA-9605063 Expression of FASN regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9607342 https://reactome.org/PathwayBrowser/#/R-HSA-9607342 Expression of FABP6 regulated by NR1H2,3 TAS Homo sapiens 76591 R-HSA-9608039 https://reactome.org/PathwayBrowser/#/R-HSA-9608039 NR1H2,3 binds the PLIN1 gene TAS Homo sapiens 76591 R-HSA-9608048 https://reactome.org/PathwayBrowser/#/R-HSA-9608048 Expression of PLIN1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9618394 https://reactome.org/PathwayBrowser/#/R-HSA-9618394 ARL4C gene transcription regulated by NR1H2,3 TAS Homo sapiens 76591 R-HSA-9618407 https://reactome.org/PathwayBrowser/#/R-HSA-9618407 NR1H2,3 binds the ARL4C gene TAS Homo sapiens 76591 R-HSA-9623365 https://reactome.org/PathwayBrowser/#/R-HSA-9623365 Expression of MYLIP regulated by NR1H2,3 TAS Homo sapiens 76591 R-HSA-9623366 https://reactome.org/PathwayBrowser/#/R-HSA-9623366 NR1H2,3 binds the MYLIP gene TAS Homo sapiens 76591 R-HSA-9624353 https://reactome.org/PathwayBrowser/#/R-HSA-9624353 NR1H2,3 binds the PLTP gene TAS Homo sapiens 76591 R-HSA-9624365 https://reactome.org/PathwayBrowser/#/R-HSA-9624365 Expression of PLTP regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9631296 https://reactome.org/PathwayBrowser/#/R-HSA-9631296 NR1H2,3 binds the FABP6 gene TAS Homo sapiens 76591 R-HSA-9657767 https://reactome.org/PathwayBrowser/#/R-HSA-9657767 Expression of APOD regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9657775 https://reactome.org/PathwayBrowser/#/R-HSA-9657775 Expression of ANGPTL3 regulated by NR1H2 or NR1H3 TAS Homo sapiens 76591 R-HSA-9657786 https://reactome.org/PathwayBrowser/#/R-HSA-9657786 NR1H2,3 binds the APOD gene TAS Homo sapiens 76591 R-HSA-9657836 https://reactome.org/PathwayBrowser/#/R-HSA-9657836 NR1H2,3 binds the ANGPTL3 gene TAS Homo sapiens 76591 R-MMU-9024326 https://reactome.org/PathwayBrowser/#/R-MMU-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Mus musculus 76591 R-MMU-9024334 https://reactome.org/PathwayBrowser/#/R-MMU-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Mus musculus 76591 R-MMU-9029517 https://reactome.org/PathwayBrowser/#/R-MMU-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Mus musculus 76591 R-MMU-9029551 https://reactome.org/PathwayBrowser/#/R-MMU-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Mus musculus 76591 R-MMU-9029561 https://reactome.org/PathwayBrowser/#/R-MMU-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Mus musculus 76591 R-MMU-9029566 https://reactome.org/PathwayBrowser/#/R-MMU-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Mus musculus 76591 R-MMU-9029580 https://reactome.org/PathwayBrowser/#/R-MMU-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Mus musculus 76591 R-MMU-9038029 https://reactome.org/PathwayBrowser/#/R-MMU-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Mus musculus 76591 R-RNO-9024326 https://reactome.org/PathwayBrowser/#/R-RNO-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Rattus norvegicus 76591 R-RNO-9024334 https://reactome.org/PathwayBrowser/#/R-RNO-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Rattus norvegicus 76591 R-RNO-9029517 https://reactome.org/PathwayBrowser/#/R-RNO-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Rattus norvegicus 76591 R-RNO-9029551 https://reactome.org/PathwayBrowser/#/R-RNO-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Rattus norvegicus 76591 R-RNO-9029561 https://reactome.org/PathwayBrowser/#/R-RNO-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Rattus norvegicus 76591 R-RNO-9029566 https://reactome.org/PathwayBrowser/#/R-RNO-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Rattus norvegicus 76591 R-RNO-9029580 https://reactome.org/PathwayBrowser/#/R-RNO-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Rattus norvegicus 76591 R-RNO-9038029 https://reactome.org/PathwayBrowser/#/R-RNO-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Rattus norvegicus 76591 R-SSC-9024326 https://reactome.org/PathwayBrowser/#/R-SSC-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Sus scrofa 76591 R-SSC-9024334 https://reactome.org/PathwayBrowser/#/R-SSC-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Sus scrofa 76591 R-SSC-9029517 https://reactome.org/PathwayBrowser/#/R-SSC-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Sus scrofa 76591 R-SSC-9029551 https://reactome.org/PathwayBrowser/#/R-SSC-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Sus scrofa 76591 R-SSC-9029561 https://reactome.org/PathwayBrowser/#/R-SSC-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Sus scrofa 76591 R-SSC-9029566 https://reactome.org/PathwayBrowser/#/R-SSC-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Sus scrofa 76591 R-SSC-9029580 https://reactome.org/PathwayBrowser/#/R-SSC-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Sus scrofa 76591 R-SSC-9038029 https://reactome.org/PathwayBrowser/#/R-SSC-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Sus scrofa 76591 R-XTR-9024326 https://reactome.org/PathwayBrowser/#/R-XTR-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Xenopus tropicalis 76591 R-XTR-9024334 https://reactome.org/PathwayBrowser/#/R-XTR-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Xenopus tropicalis 76591 R-XTR-9029517 https://reactome.org/PathwayBrowser/#/R-XTR-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Xenopus tropicalis 76591 R-XTR-9029566 https://reactome.org/PathwayBrowser/#/R-XTR-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Xenopus tropicalis 76591 R-XTR-9038029 https://reactome.org/PathwayBrowser/#/R-XTR-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Xenopus tropicalis 76792 R-HSA-5220990 https://reactome.org/PathwayBrowser/#/R-HSA-5220990 TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine IEA Homo sapiens 76792 R-HSA-5221014 https://reactome.org/PathwayBrowser/#/R-HSA-5221014 TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine IEA Homo sapiens 76792 R-HSA-9817458 https://reactome.org/PathwayBrowser/#/R-HSA-9817458 TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 IEA Homo sapiens 76792 R-MMU-5220931 https://reactome.org/PathwayBrowser/#/R-MMU-5220931 Tet1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine TAS Mus musculus 76792 R-MMU-5220944 https://reactome.org/PathwayBrowser/#/R-MMU-5220944 Tet1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine TAS Mus musculus 76792 R-MMU-9817463 https://reactome.org/PathwayBrowser/#/R-MMU-9817463 Tet3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 dimethylated on lysine-9 TAS Mus musculus 76793 R-BTA-5221061 https://reactome.org/PathwayBrowser/#/R-BTA-5221061 TDG excises 5-carboxylcytosine IEA Bos taurus 76793 R-CFA-5221061 https://reactome.org/PathwayBrowser/#/R-CFA-5221061 TDG excises 5-carboxylcytosine IEA Canis familiaris 76793 R-DME-5221061 https://reactome.org/PathwayBrowser/#/R-DME-5221061 TDG excises 5-carboxylcytosine IEA Drosophila melanogaster 76793 R-DRE-5221061 https://reactome.org/PathwayBrowser/#/R-DRE-5221061 TDG excises 5-carboxylcytosine IEA Danio rerio 76793 R-GGA-5221061 https://reactome.org/PathwayBrowser/#/R-GGA-5221061 TDG excises 5-carboxylcytosine IEA Gallus gallus 76793 R-HSA-5220952 https://reactome.org/PathwayBrowser/#/R-HSA-5220952 TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine IEA Homo sapiens 76793 R-HSA-5221061 https://reactome.org/PathwayBrowser/#/R-HSA-5221061 TDG excises 5-carboxylcytosine TAS Homo sapiens 76793 R-MMU-5220936 https://reactome.org/PathwayBrowser/#/R-MMU-5220936 Tet1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine TAS Mus musculus 76793 R-MMU-5221061 https://reactome.org/PathwayBrowser/#/R-MMU-5221061 TDG excises 5-carboxylcytosine IEA Mus musculus 76793 R-RNO-5221061 https://reactome.org/PathwayBrowser/#/R-RNO-5221061 TDG excises 5-carboxylcytosine IEA Rattus norvegicus 76793 R-SPO-5221061 https://reactome.org/PathwayBrowser/#/R-SPO-5221061 TDG excises 5-carboxylcytosine IEA Schizosaccharomyces pombe 76793 R-SSC-5221061 https://reactome.org/PathwayBrowser/#/R-SSC-5221061 TDG excises 5-carboxylcytosine IEA Sus scrofa 76793 R-XTR-5221061 https://reactome.org/PathwayBrowser/#/R-XTR-5221061 TDG excises 5-carboxylcytosine IEA Xenopus tropicalis 76794 R-BTA-5220959 https://reactome.org/PathwayBrowser/#/R-BTA-5220959 TDG excises 5-formylcytosine IEA Bos taurus 76794 R-CFA-5220959 https://reactome.org/PathwayBrowser/#/R-CFA-5220959 TDG excises 5-formylcytosine IEA Canis familiaris 76794 R-DME-5220959 https://reactome.org/PathwayBrowser/#/R-DME-5220959 TDG excises 5-formylcytosine IEA Drosophila melanogaster 76794 R-DRE-5220959 https://reactome.org/PathwayBrowser/#/R-DRE-5220959 TDG excises 5-formylcytosine IEA Danio rerio 76794 R-GGA-5220959 https://reactome.org/PathwayBrowser/#/R-GGA-5220959 TDG excises 5-formylcytosine IEA Gallus gallus 76794 R-HSA-5220952 https://reactome.org/PathwayBrowser/#/R-HSA-5220952 TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine IEA Homo sapiens 76794 R-HSA-5220959 https://reactome.org/PathwayBrowser/#/R-HSA-5220959 TDG excises 5-formylcytosine TAS Homo sapiens 76794 R-HSA-5220990 https://reactome.org/PathwayBrowser/#/R-HSA-5220990 TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine IEA Homo sapiens 76794 R-MMU-5220931 https://reactome.org/PathwayBrowser/#/R-MMU-5220931 Tet1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine TAS Mus musculus 76794 R-MMU-5220936 https://reactome.org/PathwayBrowser/#/R-MMU-5220936 Tet1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine TAS Mus musculus 76794 R-MMU-5220959 https://reactome.org/PathwayBrowser/#/R-MMU-5220959 TDG excises 5-formylcytosine IEA Mus musculus 76794 R-RNO-5220959 https://reactome.org/PathwayBrowser/#/R-RNO-5220959 TDG excises 5-formylcytosine IEA Rattus norvegicus 76794 R-SPO-5220959 https://reactome.org/PathwayBrowser/#/R-SPO-5220959 TDG excises 5-formylcytosine IEA Schizosaccharomyces pombe 76794 R-SSC-5220959 https://reactome.org/PathwayBrowser/#/R-SSC-5220959 TDG excises 5-formylcytosine IEA Sus scrofa 76794 R-XTR-5220959 https://reactome.org/PathwayBrowser/#/R-XTR-5220959 TDG excises 5-formylcytosine IEA Xenopus tropicalis 76931 R-BTA-5693783 https://reactome.org/PathwayBrowser/#/R-BTA-5693783 NAALADases hydrolyse NAAG IEA Bos taurus 76931 R-BTA-8942575 https://reactome.org/PathwayBrowser/#/R-BTA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Bos taurus 76931 R-CEL-5693783 https://reactome.org/PathwayBrowser/#/R-CEL-5693783 NAALADases hydrolyse NAAG IEA Caenorhabditis elegans 76931 R-CFA-5693783 https://reactome.org/PathwayBrowser/#/R-CFA-5693783 NAALADases hydrolyse NAAG IEA Canis familiaris 76931 R-CFA-8942575 https://reactome.org/PathwayBrowser/#/R-CFA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Canis familiaris 76931 R-DRE-5693783 https://reactome.org/PathwayBrowser/#/R-DRE-5693783 NAALADases hydrolyse NAAG IEA Danio rerio 76931 R-DRE-8942575 https://reactome.org/PathwayBrowser/#/R-DRE-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Danio rerio 76931 R-GGA-5693783 https://reactome.org/PathwayBrowser/#/R-GGA-5693783 NAALADases hydrolyse NAAG IEA Gallus gallus 76931 R-GGA-8942575 https://reactome.org/PathwayBrowser/#/R-GGA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Gallus gallus 76931 R-HSA-5693783 https://reactome.org/PathwayBrowser/#/R-HSA-5693783 NAALADases hydrolyse NAAG TAS Homo sapiens 76931 R-HSA-8942575 https://reactome.org/PathwayBrowser/#/R-HSA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG TAS Homo sapiens 76931 R-MMU-5693783 https://reactome.org/PathwayBrowser/#/R-MMU-5693783 NAALADases hydrolyse NAAG IEA Mus musculus 76931 R-MMU-8942575 https://reactome.org/PathwayBrowser/#/R-MMU-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Mus musculus 76931 R-RNO-5693783 https://reactome.org/PathwayBrowser/#/R-RNO-5693783 NAALADases hydrolyse NAAG IEA Rattus norvegicus 76931 R-RNO-8942575 https://reactome.org/PathwayBrowser/#/R-RNO-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Rattus norvegicus 76931 R-SCE-5693783 https://reactome.org/PathwayBrowser/#/R-SCE-5693783 NAALADases hydrolyse NAAG IEA Saccharomyces cerevisiae 76931 R-SPO-5693783 https://reactome.org/PathwayBrowser/#/R-SPO-5693783 NAALADases hydrolyse NAAG IEA Schizosaccharomyces pombe 76931 R-SSC-5693783 https://reactome.org/PathwayBrowser/#/R-SSC-5693783 NAALADases hydrolyse NAAG IEA Sus scrofa 76931 R-SSC-8942575 https://reactome.org/PathwayBrowser/#/R-SSC-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Sus scrofa 76931 R-XTR-5693783 https://reactome.org/PathwayBrowser/#/R-XTR-5693783 NAALADases hydrolyse NAAG IEA Xenopus tropicalis 76931 R-XTR-8942575 https://reactome.org/PathwayBrowser/#/R-XTR-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Xenopus tropicalis 76941 R-BTA-428273 https://reactome.org/PathwayBrowser/#/R-BTA-428273 SPHK1 phosphorylates sphingoid IEA Bos taurus 76941 R-BTA-428664 https://reactome.org/PathwayBrowser/#/R-BTA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Bos taurus 76941 R-BTA-9695890 https://reactome.org/PathwayBrowser/#/R-BTA-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Bos taurus 76941 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 76941 R-CEL-428273 https://reactome.org/PathwayBrowser/#/R-CEL-428273 SPHK1 phosphorylates sphingoid IEA Caenorhabditis elegans 76941 R-CEL-9695890 https://reactome.org/PathwayBrowser/#/R-CEL-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Caenorhabditis elegans 76941 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 76941 R-CFA-428273 https://reactome.org/PathwayBrowser/#/R-CFA-428273 SPHK1 phosphorylates sphingoid IEA Canis familiaris 76941 R-CFA-428664 https://reactome.org/PathwayBrowser/#/R-CFA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Canis familiaris 76941 R-CFA-9695890 https://reactome.org/PathwayBrowser/#/R-CFA-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Canis familiaris 76941 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 76941 R-DDI-428273 https://reactome.org/PathwayBrowser/#/R-DDI-428273 SPHK1 phosphorylates sphingoid IEA Dictyostelium discoideum 76941 R-DDI-428664 https://reactome.org/PathwayBrowser/#/R-DDI-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Dictyostelium discoideum 76941 R-DDI-9695890 https://reactome.org/PathwayBrowser/#/R-DDI-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Dictyostelium discoideum 76941 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 76941 R-DME-428273 https://reactome.org/PathwayBrowser/#/R-DME-428273 SPHK1 phosphorylates sphingoid IEA Drosophila melanogaster 76941 R-DME-9695890 https://reactome.org/PathwayBrowser/#/R-DME-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Drosophila melanogaster 76941 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 76941 R-DRE-9695890 https://reactome.org/PathwayBrowser/#/R-DRE-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Danio rerio 76941 R-GGA-428273 https://reactome.org/PathwayBrowser/#/R-GGA-428273 SPHK1 phosphorylates sphingoid IEA Gallus gallus 76941 R-GGA-428664 https://reactome.org/PathwayBrowser/#/R-GGA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Gallus gallus 76941 R-GGA-9695890 https://reactome.org/PathwayBrowser/#/R-GGA-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Gallus gallus 76941 R-HSA-428273 https://reactome.org/PathwayBrowser/#/R-HSA-428273 SPHK1 phosphorylates sphingoid TAS Homo sapiens 76941 R-HSA-428664 https://reactome.org/PathwayBrowser/#/R-HSA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates TAS Homo sapiens 76941 R-HSA-9695890 https://reactome.org/PathwayBrowser/#/R-HSA-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region TAS Homo sapiens 76941 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 76941 R-MMU-428273 https://reactome.org/PathwayBrowser/#/R-MMU-428273 SPHK1 phosphorylates sphingoid IEA Mus musculus 76941 R-MMU-428664 https://reactome.org/PathwayBrowser/#/R-MMU-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Mus musculus 76941 R-MMU-9695890 https://reactome.org/PathwayBrowser/#/R-MMU-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Mus musculus 76941 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 76941 R-PFA-9695890 https://reactome.org/PathwayBrowser/#/R-PFA-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Plasmodium falciparum 76941 R-RNO-428273 https://reactome.org/PathwayBrowser/#/R-RNO-428273 SPHK1 phosphorylates sphingoid IEA Rattus norvegicus 76941 R-RNO-428664 https://reactome.org/PathwayBrowser/#/R-RNO-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Rattus norvegicus 76941 R-RNO-9695890 https://reactome.org/PathwayBrowser/#/R-RNO-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Rattus norvegicus 76941 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 76941 R-SCE-428273 https://reactome.org/PathwayBrowser/#/R-SCE-428273 SPHK1 phosphorylates sphingoid IEA Saccharomyces cerevisiae 76941 R-SCE-428664 https://reactome.org/PathwayBrowser/#/R-SCE-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Saccharomyces cerevisiae 76941 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 76941 R-SPO-428273 https://reactome.org/PathwayBrowser/#/R-SPO-428273 SPHK1 phosphorylates sphingoid IEA Schizosaccharomyces pombe 76941 R-SPO-428664 https://reactome.org/PathwayBrowser/#/R-SPO-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Schizosaccharomyces pombe 76941 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 76941 R-SSC-428273 https://reactome.org/PathwayBrowser/#/R-SSC-428273 SPHK1 phosphorylates sphingoid IEA Sus scrofa 76941 R-SSC-428664 https://reactome.org/PathwayBrowser/#/R-SSC-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Sus scrofa 76941 R-SSC-9695890 https://reactome.org/PathwayBrowser/#/R-SSC-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Sus scrofa 76941 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 76941 R-XTR-428664 https://reactome.org/PathwayBrowser/#/R-XTR-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Xenopus tropicalis 76941 R-XTR-9695890 https://reactome.org/PathwayBrowser/#/R-XTR-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Xenopus tropicalis 76941 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 77008 R-HSA-5333607 https://reactome.org/PathwayBrowser/#/R-HSA-5333607 GSSeH combines with bGalNAc derivative to form GSSebGalNac IEA Homo sapiens 77008 R-HSA-5333608 https://reactome.org/PathwayBrowser/#/R-HSA-5333608 GSSebGalNac is reduced and methylated to MeSebGalNac IEA Homo sapiens 77008 R-RNO-5333614 https://reactome.org/PathwayBrowser/#/R-RNO-5333614 GSSebGalNac is reduced and methylated to MeSebGalNac TAS Rattus norvegicus 77008 R-RNO-5333617 https://reactome.org/PathwayBrowser/#/R-RNO-5333617 GSSeH combines with bGalNAc derivative to form GSSebGalNac TAS Rattus norvegicus 77010 R-HSA-5333608 https://reactome.org/PathwayBrowser/#/R-HSA-5333608 GSSebGalNac is reduced and methylated to MeSebGalNac IEA Homo sapiens 77010 R-HSA-5333609 https://reactome.org/PathwayBrowser/#/R-HSA-5333609 MeSebGalNac is hydrolysed to MeSeH and bGalNac IEA Homo sapiens 77010 R-HSA-5333612 https://reactome.org/PathwayBrowser/#/R-HSA-5333612 MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal IEA Homo sapiens 77010 R-RNO-5333611 https://reactome.org/PathwayBrowser/#/R-RNO-5333611 MeSebGalNac is hydrolysed to MeSeH and bGalNac TAS Rattus norvegicus 77010 R-RNO-5333613 https://reactome.org/PathwayBrowser/#/R-RNO-5333613 MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal TAS Rattus norvegicus 77010 R-RNO-5333614 https://reactome.org/PathwayBrowser/#/R-RNO-5333614 GSSebGalNac is reduced and methylated to MeSebGalNac TAS Rattus norvegicus 77012 R-BTA-5263616 https://reactome.org/PathwayBrowser/#/R-BTA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Bos taurus 77012 R-CEL-5263616 https://reactome.org/PathwayBrowser/#/R-CEL-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Caenorhabditis elegans 77012 R-GGA-5263616 https://reactome.org/PathwayBrowser/#/R-GGA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Gallus gallus 77012 R-HSA-5263616 https://reactome.org/PathwayBrowser/#/R-HSA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 TAS Homo sapiens 77012 R-HSA-5333612 https://reactome.org/PathwayBrowser/#/R-HSA-5333612 MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal IEA Homo sapiens 77012 R-MMU-5263616 https://reactome.org/PathwayBrowser/#/R-MMU-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Mus musculus 77012 R-PFA-5263616 https://reactome.org/PathwayBrowser/#/R-PFA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Plasmodium falciparum 77012 R-RNO-5263616 https://reactome.org/PathwayBrowser/#/R-RNO-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Rattus norvegicus 77012 R-RNO-5333613 https://reactome.org/PathwayBrowser/#/R-RNO-5333613 MeSebGalNac is oxidatively cleaved to MeSeO2H and 2-acetamidoglucal TAS Rattus norvegicus 77016 R-BTA-2066779 https://reactome.org/PathwayBrowser/#/R-BTA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Bos taurus 77016 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 77016 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 77016 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 77016 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 77016 R-BTA-9020261 https://reactome.org/PathwayBrowser/#/R-BTA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Bos taurus 77016 R-BTA-9020274 https://reactome.org/PathwayBrowser/#/R-BTA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Bos taurus 77016 R-BTA-9020275 https://reactome.org/PathwayBrowser/#/R-BTA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Bos taurus 77016 R-BTA-9027043 https://reactome.org/PathwayBrowser/#/R-BTA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Bos taurus 77016 R-BTA-9027532 https://reactome.org/PathwayBrowser/#/R-BTA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Bos taurus 77016 R-BTA-9027624 https://reactome.org/PathwayBrowser/#/R-BTA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Bos taurus 77016 R-BTA-9027627 https://reactome.org/PathwayBrowser/#/R-BTA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Bos taurus 77016 R-CEL-2066779 https://reactome.org/PathwayBrowser/#/R-CEL-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Caenorhabditis elegans 77016 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 77016 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 77016 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 77016 R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans 77016 R-CFA-2066779 https://reactome.org/PathwayBrowser/#/R-CFA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Canis familiaris 77016 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 77016 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 77016 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 77016 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 77016 R-CFA-9020261 https://reactome.org/PathwayBrowser/#/R-CFA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Canis familiaris 77016 R-CFA-9020274 https://reactome.org/PathwayBrowser/#/R-CFA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Canis familiaris 77016 R-CFA-9020275 https://reactome.org/PathwayBrowser/#/R-CFA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Canis familiaris 77016 R-CFA-9027043 https://reactome.org/PathwayBrowser/#/R-CFA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Canis familiaris 77016 R-CFA-9027532 https://reactome.org/PathwayBrowser/#/R-CFA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Canis familiaris 77016 R-CFA-9027624 https://reactome.org/PathwayBrowser/#/R-CFA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Canis familiaris 77016 R-CFA-9027627 https://reactome.org/PathwayBrowser/#/R-CFA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Canis familiaris 77016 R-DDI-9020274 https://reactome.org/PathwayBrowser/#/R-DDI-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Dictyostelium discoideum 77016 R-DDI-9020275 https://reactome.org/PathwayBrowser/#/R-DDI-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Dictyostelium discoideum 77016 R-DDI-9027043 https://reactome.org/PathwayBrowser/#/R-DDI-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Dictyostelium discoideum 77016 R-DDI-9027624 https://reactome.org/PathwayBrowser/#/R-DDI-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Dictyostelium discoideum 77016 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 77016 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 77016 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 77016 R-DME-9027043 https://reactome.org/PathwayBrowser/#/R-DME-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Drosophila melanogaster 77016 R-DRE-2066779 https://reactome.org/PathwayBrowser/#/R-DRE-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Danio rerio 77016 R-DRE-9020261 https://reactome.org/PathwayBrowser/#/R-DRE-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Danio rerio 77016 R-DRE-9020274 https://reactome.org/PathwayBrowser/#/R-DRE-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Danio rerio 77016 R-DRE-9020275 https://reactome.org/PathwayBrowser/#/R-DRE-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Danio rerio 77016 R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio 77016 R-DRE-9027532 https://reactome.org/PathwayBrowser/#/R-DRE-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Danio rerio 77016 R-DRE-9027624 https://reactome.org/PathwayBrowser/#/R-DRE-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Danio rerio 77016 R-DRE-9027627 https://reactome.org/PathwayBrowser/#/R-DRE-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Danio rerio 77016 R-GGA-2066779 https://reactome.org/PathwayBrowser/#/R-GGA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Gallus gallus 77016 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 77016 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 77016 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 77016 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 77016 R-GGA-9020261 https://reactome.org/PathwayBrowser/#/R-GGA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Gallus gallus 77016 R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus 77016 R-GGA-9027532 https://reactome.org/PathwayBrowser/#/R-GGA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Gallus gallus 77016 R-GGA-9027624 https://reactome.org/PathwayBrowser/#/R-GGA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Gallus gallus 77016 R-GGA-9027627 https://reactome.org/PathwayBrowser/#/R-GGA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Gallus gallus 77016 R-HSA-2066779 https://reactome.org/PathwayBrowser/#/R-HSA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) TAS Homo sapiens 77016 R-HSA-2066785 https://reactome.org/PathwayBrowser/#/R-HSA-2066785 Retranslocation of DHA back to ER TAS Homo sapiens 77016 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 77016 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 77016 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 77016 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 77016 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 77016 R-HSA-9020261 https://reactome.org/PathwayBrowser/#/R-HSA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA TAS Homo sapiens 77016 R-HSA-9020274 https://reactome.org/PathwayBrowser/#/R-HSA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA TAS Homo sapiens 77016 R-HSA-9020275 https://reactome.org/PathwayBrowser/#/R-HSA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA TAS Homo sapiens 77016 R-HSA-9027043 https://reactome.org/PathwayBrowser/#/R-HSA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA TAS Homo sapiens 77016 R-HSA-9027532 https://reactome.org/PathwayBrowser/#/R-HSA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA TAS Homo sapiens 77016 R-HSA-9027624 https://reactome.org/PathwayBrowser/#/R-HSA-9027624 ALOX5 oxidises DHA to 7-HDHA TAS Homo sapiens 77016 R-HSA-9027627 https://reactome.org/PathwayBrowser/#/R-HSA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) TAS Homo sapiens 77016 R-MMU-2066779 https://reactome.org/PathwayBrowser/#/R-MMU-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Mus musculus 77016 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 77016 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 77016 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 77016 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 77016 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 77016 R-MMU-9020261 https://reactome.org/PathwayBrowser/#/R-MMU-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Mus musculus 77016 R-MMU-9020274 https://reactome.org/PathwayBrowser/#/R-MMU-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Mus musculus 77016 R-MMU-9020275 https://reactome.org/PathwayBrowser/#/R-MMU-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Mus musculus 77016 R-MMU-9027043 https://reactome.org/PathwayBrowser/#/R-MMU-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Mus musculus 77016 R-MMU-9027532 https://reactome.org/PathwayBrowser/#/R-MMU-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Mus musculus 77016 R-MMU-9027624 https://reactome.org/PathwayBrowser/#/R-MMU-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Mus musculus 77016 R-MMU-9027627 https://reactome.org/PathwayBrowser/#/R-MMU-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Mus musculus 77016 R-RNO-2066779 https://reactome.org/PathwayBrowser/#/R-RNO-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Rattus norvegicus 77016 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 77016 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 77016 R-RNO-9020261 https://reactome.org/PathwayBrowser/#/R-RNO-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Rattus norvegicus 77016 R-RNO-9020274 https://reactome.org/PathwayBrowser/#/R-RNO-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Rattus norvegicus 77016 R-RNO-9020275 https://reactome.org/PathwayBrowser/#/R-RNO-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Rattus norvegicus 77016 R-RNO-9027043 https://reactome.org/PathwayBrowser/#/R-RNO-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Rattus norvegicus 77016 R-RNO-9027532 https://reactome.org/PathwayBrowser/#/R-RNO-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Rattus norvegicus 77016 R-RNO-9027624 https://reactome.org/PathwayBrowser/#/R-RNO-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Rattus norvegicus 77016 R-RNO-9027627 https://reactome.org/PathwayBrowser/#/R-RNO-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Rattus norvegicus 77016 R-SCE-2066779 https://reactome.org/PathwayBrowser/#/R-SCE-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Saccharomyces cerevisiae 77016 R-SSC-2066779 https://reactome.org/PathwayBrowser/#/R-SSC-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Sus scrofa 77016 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 77016 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 77016 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 77016 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 77016 R-SSC-9020261 https://reactome.org/PathwayBrowser/#/R-SSC-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Sus scrofa 77016 R-SSC-9020274 https://reactome.org/PathwayBrowser/#/R-SSC-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Sus scrofa 77016 R-SSC-9020275 https://reactome.org/PathwayBrowser/#/R-SSC-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Sus scrofa 77016 R-SSC-9027043 https://reactome.org/PathwayBrowser/#/R-SSC-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Sus scrofa 77016 R-SSC-9027532 https://reactome.org/PathwayBrowser/#/R-SSC-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Sus scrofa 77016 R-SSC-9027624 https://reactome.org/PathwayBrowser/#/R-SSC-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Sus scrofa 77016 R-SSC-9027627 https://reactome.org/PathwayBrowser/#/R-SSC-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Sus scrofa 77016 R-XTR-2066779 https://reactome.org/PathwayBrowser/#/R-XTR-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Xenopus tropicalis 77016 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 77016 R-XTR-9020261 https://reactome.org/PathwayBrowser/#/R-XTR-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Xenopus tropicalis 77016 R-XTR-9027043 https://reactome.org/PathwayBrowser/#/R-XTR-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Xenopus tropicalis 77016 R-XTR-9027532 https://reactome.org/PathwayBrowser/#/R-XTR-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Xenopus tropicalis 77016 R-XTR-9027624 https://reactome.org/PathwayBrowser/#/R-XTR-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Xenopus tropicalis 77016 R-XTR-9027627 https://reactome.org/PathwayBrowser/#/R-XTR-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Xenopus tropicalis 77028 R-HSA-2408532 https://reactome.org/PathwayBrowser/#/R-HSA-2408532 AdeSeHCys is hydrolysed to SeHCys by AHCY IEA Homo sapiens 77028 R-HSA-2408544 https://reactome.org/PathwayBrowser/#/R-HSA-2408544 AdoSeMet is converted to AdeSeHCys by MetTrans(1) IEA Homo sapiens 77028 R-RNO-2408512 https://reactome.org/PathwayBrowser/#/R-RNO-2408512 AdeSeHCys is hydrolysed to SeHCys by Ahcy TAS Rattus norvegicus 77028 R-RNO-2408545 https://reactome.org/PathwayBrowser/#/R-RNO-2408545 AdoSeMet is converted to AdeSeHCys by MetTrans(2) TAS Rattus norvegicus 77058 R-HSA-2408554 https://reactome.org/PathwayBrowser/#/R-HSA-2408554 Me2Se is methylated to Me3Se+ by INMT IEA Homo sapiens 77058 R-MMU-2408549 https://reactome.org/PathwayBrowser/#/R-MMU-2408549 Me2Se is methylated to Me3Se+ by Inmt TAS Mus musculus 77062 R-BTA-5263614 https://reactome.org/PathwayBrowser/#/R-BTA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Bos taurus 77062 R-BTA-5263616 https://reactome.org/PathwayBrowser/#/R-BTA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Bos taurus 77062 R-CEL-5263614 https://reactome.org/PathwayBrowser/#/R-CEL-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Caenorhabditis elegans 77062 R-CEL-5263616 https://reactome.org/PathwayBrowser/#/R-CEL-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Caenorhabditis elegans 77062 R-GGA-5263614 https://reactome.org/PathwayBrowser/#/R-GGA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Gallus gallus 77062 R-GGA-5263616 https://reactome.org/PathwayBrowser/#/R-GGA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Gallus gallus 77062 R-HSA-5263614 https://reactome.org/PathwayBrowser/#/R-HSA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 TAS Homo sapiens 77062 R-HSA-5263616 https://reactome.org/PathwayBrowser/#/R-HSA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 TAS Homo sapiens 77062 R-MMU-5263614 https://reactome.org/PathwayBrowser/#/R-MMU-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Mus musculus 77062 R-MMU-5263616 https://reactome.org/PathwayBrowser/#/R-MMU-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Mus musculus 77062 R-PFA-5263614 https://reactome.org/PathwayBrowser/#/R-PFA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Plasmodium falciparum 77062 R-PFA-5263616 https://reactome.org/PathwayBrowser/#/R-PFA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Plasmodium falciparum 77062 R-RNO-5263614 https://reactome.org/PathwayBrowser/#/R-RNO-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Rattus norvegicus 77062 R-RNO-5263616 https://reactome.org/PathwayBrowser/#/R-RNO-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Rattus norvegicus 77224 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 77224 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 77224 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 77224 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 77224 R-BTA-9026003 https://reactome.org/PathwayBrowser/#/R-BTA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Bos taurus 77224 R-BTA-9026006 https://reactome.org/PathwayBrowser/#/R-BTA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Bos taurus 77224 R-BTA-9026408 https://reactome.org/PathwayBrowser/#/R-BTA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Bos taurus 77224 R-BTA-9027607 https://reactome.org/PathwayBrowser/#/R-BTA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Bos taurus 77224 R-BTA-9027633 https://reactome.org/PathwayBrowser/#/R-BTA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Bos taurus 77224 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 77224 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 77224 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 77224 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 77224 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 77224 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 77224 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 77224 R-CFA-9026003 https://reactome.org/PathwayBrowser/#/R-CFA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Canis familiaris 77224 R-CFA-9026006 https://reactome.org/PathwayBrowser/#/R-CFA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Canis familiaris 77224 R-CFA-9026408 https://reactome.org/PathwayBrowser/#/R-CFA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Canis familiaris 77224 R-CFA-9027607 https://reactome.org/PathwayBrowser/#/R-CFA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Canis familiaris 77224 R-CFA-9027633 https://reactome.org/PathwayBrowser/#/R-CFA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Canis familiaris 77224 R-DDI-9026003 https://reactome.org/PathwayBrowser/#/R-DDI-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Dictyostelium discoideum 77224 R-DDI-9026006 https://reactome.org/PathwayBrowser/#/R-DDI-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Dictyostelium discoideum 77224 R-DDI-9027633 https://reactome.org/PathwayBrowser/#/R-DDI-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Dictyostelium discoideum 77224 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 77224 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 77224 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 77224 R-DRE-9026003 https://reactome.org/PathwayBrowser/#/R-DRE-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Danio rerio 77224 R-DRE-9026006 https://reactome.org/PathwayBrowser/#/R-DRE-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Danio rerio 77224 R-DRE-9026408 https://reactome.org/PathwayBrowser/#/R-DRE-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Danio rerio 77224 R-DRE-9027607 https://reactome.org/PathwayBrowser/#/R-DRE-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Danio rerio 77224 R-DRE-9027633 https://reactome.org/PathwayBrowser/#/R-DRE-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Danio rerio 77224 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 77224 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 77224 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 77224 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 77224 R-GGA-9026408 https://reactome.org/PathwayBrowser/#/R-GGA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Gallus gallus 77224 R-GGA-9027607 https://reactome.org/PathwayBrowser/#/R-GGA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Gallus gallus 77224 R-GGA-9027633 https://reactome.org/PathwayBrowser/#/R-GGA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Gallus gallus 77224 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 77224 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 77224 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 77224 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 77224 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 77224 R-HSA-9026003 https://reactome.org/PathwayBrowser/#/R-HSA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 TAS Homo sapiens 77224 R-HSA-9026006 https://reactome.org/PathwayBrowser/#/R-HSA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 TAS Homo sapiens 77224 R-HSA-9026408 https://reactome.org/PathwayBrowser/#/R-HSA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 TAS Homo sapiens 77224 R-HSA-9027607 https://reactome.org/PathwayBrowser/#/R-HSA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 TAS Homo sapiens 77224 R-HSA-9027633 https://reactome.org/PathwayBrowser/#/R-HSA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 TAS Homo sapiens 77224 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 77224 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 77224 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 77224 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 77224 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 77224 R-MMU-9026003 https://reactome.org/PathwayBrowser/#/R-MMU-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Mus musculus 77224 R-MMU-9026006 https://reactome.org/PathwayBrowser/#/R-MMU-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Mus musculus 77224 R-MMU-9026408 https://reactome.org/PathwayBrowser/#/R-MMU-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Mus musculus 77224 R-MMU-9027607 https://reactome.org/PathwayBrowser/#/R-MMU-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Mus musculus 77224 R-MMU-9027633 https://reactome.org/PathwayBrowser/#/R-MMU-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Mus musculus 77224 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 77224 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 77224 R-RNO-9026003 https://reactome.org/PathwayBrowser/#/R-RNO-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Rattus norvegicus 77224 R-RNO-9026006 https://reactome.org/PathwayBrowser/#/R-RNO-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Rattus norvegicus 77224 R-RNO-9026408 https://reactome.org/PathwayBrowser/#/R-RNO-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Rattus norvegicus 77224 R-RNO-9027607 https://reactome.org/PathwayBrowser/#/R-RNO-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Rattus norvegicus 77224 R-RNO-9027633 https://reactome.org/PathwayBrowser/#/R-RNO-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Rattus norvegicus 77224 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 77224 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 77224 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 77224 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 77224 R-SSC-9026003 https://reactome.org/PathwayBrowser/#/R-SSC-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Sus scrofa 77224 R-SSC-9026006 https://reactome.org/PathwayBrowser/#/R-SSC-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Sus scrofa 77224 R-SSC-9026408 https://reactome.org/PathwayBrowser/#/R-SSC-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Sus scrofa 77224 R-SSC-9027607 https://reactome.org/PathwayBrowser/#/R-SSC-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Sus scrofa 77224 R-SSC-9027633 https://reactome.org/PathwayBrowser/#/R-SSC-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Sus scrofa 77224 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 77224 R-XTR-9026408 https://reactome.org/PathwayBrowser/#/R-XTR-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Xenopus tropicalis 77224 R-XTR-9027607 https://reactome.org/PathwayBrowser/#/R-XTR-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Xenopus tropicalis 77224 R-XTR-9027633 https://reactome.org/PathwayBrowser/#/R-XTR-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Xenopus tropicalis 77268 R-BTA-389609 https://reactome.org/PathwayBrowser/#/R-BTA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Bos taurus 77268 R-BTA-389632 https://reactome.org/PathwayBrowser/#/R-BTA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Bos taurus 77268 R-CEL-389609 https://reactome.org/PathwayBrowser/#/R-CEL-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Caenorhabditis elegans 77268 R-CEL-389632 https://reactome.org/PathwayBrowser/#/R-CEL-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Caenorhabditis elegans 77268 R-CFA-389609 https://reactome.org/PathwayBrowser/#/R-CFA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Canis familiaris 77268 R-CFA-389632 https://reactome.org/PathwayBrowser/#/R-CFA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Canis familiaris 77268 R-DDI-389609 https://reactome.org/PathwayBrowser/#/R-DDI-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Dictyostelium discoideum 77268 R-DME-389609 https://reactome.org/PathwayBrowser/#/R-DME-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Drosophila melanogaster 77268 R-DME-389632 https://reactome.org/PathwayBrowser/#/R-DME-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Drosophila melanogaster 77268 R-DRE-389609 https://reactome.org/PathwayBrowser/#/R-DRE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Danio rerio 77268 R-GGA-389609 https://reactome.org/PathwayBrowser/#/R-GGA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Gallus gallus 77268 R-GGA-389632 https://reactome.org/PathwayBrowser/#/R-GGA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus 77268 R-HSA-389609 https://reactome.org/PathwayBrowser/#/R-HSA-389609 ALDH3A2-2 oxidizes pristanal to pristanate TAS Homo sapiens 77268 R-HSA-389632 https://reactome.org/PathwayBrowser/#/R-HSA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate TAS Homo sapiens 77268 R-MMU-389609 https://reactome.org/PathwayBrowser/#/R-MMU-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Mus musculus 77268 R-MMU-389632 https://reactome.org/PathwayBrowser/#/R-MMU-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Mus musculus 77268 R-RNO-389609 https://reactome.org/PathwayBrowser/#/R-RNO-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Rattus norvegicus 77268 R-RNO-389632 https://reactome.org/PathwayBrowser/#/R-RNO-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 77268 R-SCE-389609 https://reactome.org/PathwayBrowser/#/R-SCE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Saccharomyces cerevisiae 77268 R-SCE-389632 https://reactome.org/PathwayBrowser/#/R-SCE-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Saccharomyces cerevisiae 77268 R-SSC-389609 https://reactome.org/PathwayBrowser/#/R-SSC-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Sus scrofa 77268 R-SSC-389632 https://reactome.org/PathwayBrowser/#/R-SSC-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Sus scrofa 77268 R-XTR-389632 https://reactome.org/PathwayBrowser/#/R-XTR-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 7735 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 7735 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 7735 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 7735 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7735 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 7735 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 7735 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7735 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 7735 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 7735 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 7735 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 7735 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 7735 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 7735 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7735 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 7735 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 7735 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7735 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 7735 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 7735 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7735 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 7735 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 7735 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7735 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 7735 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 7735 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7735 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7735 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 77361 R-BTA-4755494 https://reactome.org/PathwayBrowser/#/R-BTA-4755494 PIAS1,2-1 SUMOylate NR5A2 with SUMO1 IEA Bos taurus 77361 R-CEL-4755494 https://reactome.org/PathwayBrowser/#/R-CEL-4755494 PIAS1,2-1 SUMOylate NR5A2 with SUMO1 IEA Caenorhabditis elegans 77361 R-GGA-4755494 https://reactome.org/PathwayBrowser/#/R-GGA-4755494 PIAS1,2-1 SUMOylate NR5A2 with SUMO1 IEA Gallus gallus 77361 R-HSA-4755494 https://reactome.org/PathwayBrowser/#/R-HSA-4755494 PIAS1,2-1 SUMOylate NR5A2 with SUMO1 TAS Homo sapiens 77361 R-MMU-4755494 https://reactome.org/PathwayBrowser/#/R-MMU-4755494 PIAS1,2-1 SUMOylate NR5A2 with SUMO1 IEA Mus musculus 77361 R-RNO-4755494 https://reactome.org/PathwayBrowser/#/R-RNO-4755494 PIAS1,2-1 SUMOylate NR5A2 with SUMO1 IEA Rattus norvegicus 77361 R-SSC-4755494 https://reactome.org/PathwayBrowser/#/R-SSC-4755494 PIAS1,2-1 SUMOylate NR5A2 with SUMO1 IEA Sus scrofa 77363 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 77363 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 77363 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 77363 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 77363 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 77363 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 77363 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 77363 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 77363 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 77363 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 77363 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 77363 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 77363 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 77363 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 77363 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 77363 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 77363 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 77363 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 77363 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 77363 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 77363 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 77363 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 77363 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 77363 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 77363 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 77363 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 77363 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 77363 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 77363 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 77363 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 77363 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 77363 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 77363 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 77364 R-BTA-162742 https://reactome.org/PathwayBrowser/#/R-BTA-162742 (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Bos taurus 77364 R-BTA-162836 https://reactome.org/PathwayBrowser/#/R-BTA-162836 uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide IEA Bos taurus 77364 R-CFA-162836 https://reactome.org/PathwayBrowser/#/R-CFA-162836 uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide IEA Canis familiaris 77364 R-DDI-162742 https://reactome.org/PathwayBrowser/#/R-DDI-162742 (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Dictyostelium discoideum 77364 R-DME-162742 https://reactome.org/PathwayBrowser/#/R-DME-162742 (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Drosophila melanogaster 77364 R-HSA-162742 https://reactome.org/PathwayBrowser/#/R-HSA-162742 (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI TAS Homo sapiens 77364 R-HSA-162836 https://reactome.org/PathwayBrowser/#/R-HSA-162836 uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide TAS Homo sapiens 77364 R-HSA-163069 https://reactome.org/PathwayBrowser/#/R-HSA-163069 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol IEA Homo sapiens 77364 R-MMU-162742 https://reactome.org/PathwayBrowser/#/R-MMU-162742 (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Mus musculus 77364 R-MMU-162836 https://reactome.org/PathwayBrowser/#/R-MMU-162836 uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide IEA Mus musculus 77364 R-RNO-162742 https://reactome.org/PathwayBrowser/#/R-RNO-162742 (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Rattus norvegicus 77364 R-RNO-162836 https://reactome.org/PathwayBrowser/#/R-RNO-162836 uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide IEA Rattus norvegicus 77364 R-SCE-162742 https://reactome.org/PathwayBrowser/#/R-SCE-162742 (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Saccharomyces cerevisiae 77364 R-SSC-162742 https://reactome.org/PathwayBrowser/#/R-SSC-162742 (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI IEA Sus scrofa 77364 R-SSC-162836 https://reactome.org/PathwayBrowser/#/R-SSC-162836 uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide IEA Sus scrofa 77480 R-CFA-8850356 https://reactome.org/PathwayBrowser/#/R-CFA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Canis familiaris 77480 R-GGA-8850356 https://reactome.org/PathwayBrowser/#/R-GGA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Gallus gallus 77480 R-HSA-8850356 https://reactome.org/PathwayBrowser/#/R-HSA-8850356 TCR binds microbial lipid-based antigen via CD1 TAS Homo sapiens 7754 R-BTA-9009936 https://reactome.org/PathwayBrowser/#/R-BTA-9009936 RNASEL cleaves cellular ssRNA IEA Bos taurus 7754 R-BTA-9009950 https://reactome.org/PathwayBrowser/#/R-BTA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Bos taurus 7754 R-CEL-9009950 https://reactome.org/PathwayBrowser/#/R-CEL-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Caenorhabditis elegans 7754 R-CFA-9009936 https://reactome.org/PathwayBrowser/#/R-CFA-9009936 RNASEL cleaves cellular ssRNA IEA Canis familiaris 7754 R-CFA-9009950 https://reactome.org/PathwayBrowser/#/R-CFA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Canis familiaris 7754 R-DME-9009950 https://reactome.org/PathwayBrowser/#/R-DME-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Drosophila melanogaster 7754 R-GGA-9009936 https://reactome.org/PathwayBrowser/#/R-GGA-9009936 RNASEL cleaves cellular ssRNA IEA Gallus gallus 7754 R-GGA-9009950 https://reactome.org/PathwayBrowser/#/R-GGA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Gallus gallus 7754 R-HSA-8983680 https://reactome.org/PathwayBrowser/#/R-HSA-8983680 OAS1 produces oligoadenylates TAS Homo sapiens 7754 R-HSA-8985091 https://reactome.org/PathwayBrowser/#/R-HSA-8985091 OAS3 produces oligoadenylates TAS Homo sapiens 7754 R-HSA-8985104 https://reactome.org/PathwayBrowser/#/R-HSA-8985104 OAS2 produces oligoadenylates TAS Homo sapiens 7754 R-HSA-8985123 https://reactome.org/PathwayBrowser/#/R-HSA-8985123 RNASEL binds 2'-5' oligoadenylate TAS Homo sapiens 7754 R-HSA-9009936 https://reactome.org/PathwayBrowser/#/R-HSA-9009936 RNASEL cleaves cellular ssRNA TAS Homo sapiens 7754 R-HSA-9009941 https://reactome.org/PathwayBrowser/#/R-HSA-9009941 RNASEL cleaves viral ssRNA TAS Homo sapiens 7754 R-HSA-9009950 https://reactome.org/PathwayBrowser/#/R-HSA-9009950 PDE12 cleaves 2'-5' oligoadenylates TAS Homo sapiens 7754 R-HSA-9615042 https://reactome.org/PathwayBrowser/#/R-HSA-9615042 Viral 2',5'-PDE cleaves 2'-5' oligoadenylates TAS Homo sapiens 7754 R-MMU-9009936 https://reactome.org/PathwayBrowser/#/R-MMU-9009936 RNASEL cleaves cellular ssRNA IEA Mus musculus 7754 R-MMU-9009950 https://reactome.org/PathwayBrowser/#/R-MMU-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Mus musculus 7754 R-RNO-9009936 https://reactome.org/PathwayBrowser/#/R-RNO-9009936 RNASEL cleaves cellular ssRNA IEA Rattus norvegicus 7754 R-RNO-9009950 https://reactome.org/PathwayBrowser/#/R-RNO-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Rattus norvegicus 7754 R-SSC-9009936 https://reactome.org/PathwayBrowser/#/R-SSC-9009936 RNASEL cleaves cellular ssRNA IEA Sus scrofa 7754 R-SSC-9009950 https://reactome.org/PathwayBrowser/#/R-SSC-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Sus scrofa 7754 R-XTR-9009936 https://reactome.org/PathwayBrowser/#/R-XTR-9009936 RNASEL cleaves cellular ssRNA IEA Xenopus tropicalis 77543 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 77543 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 77543 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 77543 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 77543 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 77543 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 77543 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 77543 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 77543 R-HSA-9731708 https://reactome.org/PathwayBrowser/#/R-HSA-9731708 nsp10:nsp14 binds to ExoN inhibitors TAS Homo sapiens 7757 R-HSA-9836585 https://reactome.org/PathwayBrowser/#/R-HSA-9836585 SUPV3L1:PNPT1 hydrolyzes mitochondrial RNA to yield 4-5 nucleotide oligoribonucleotides TAS Homo sapiens 7757 R-HSA-9836822 https://reactome.org/PathwayBrowser/#/R-HSA-9836822 REXO2 hydrolyzes 4-5 nucleotide RNAs to ribonucleotides TAS Homo sapiens 77634 R-FCA-164926 https://reactome.org/PathwayBrowser/#/R-FCA-164926 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ TAS Felis catus 77634 R-HSA-71223 https://reactome.org/PathwayBrowser/#/R-HSA-71223 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 IEA Homo sapiens 77634 R-HSA-71239 https://reactome.org/PathwayBrowser/#/R-HSA-71239 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ IEA Homo sapiens 77634 R-RNO-71234 https://reactome.org/PathwayBrowser/#/R-RNO-71234 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 [rat] TAS Rattus norvegicus 77635 R-BTA-5340124 https://reactome.org/PathwayBrowser/#/R-BTA-5340124 CSN polymer binds CaPO4 IEA Bos taurus 77635 R-CFA-5340124 https://reactome.org/PathwayBrowser/#/R-CFA-5340124 CSN polymer binds CaPO4 IEA Canis familiaris 77635 R-HSA-5340124 https://reactome.org/PathwayBrowser/#/R-HSA-5340124 CSN polymer binds CaPO4 TAS Homo sapiens 77635 R-MMU-5340124 https://reactome.org/PathwayBrowser/#/R-MMU-5340124 CSN polymer binds CaPO4 IEA Mus musculus 77635 R-RNO-5340124 https://reactome.org/PathwayBrowser/#/R-RNO-5340124 CSN polymer binds CaPO4 IEA Rattus norvegicus 77635 R-SSC-5340124 https://reactome.org/PathwayBrowser/#/R-SSC-5340124 CSN polymer binds CaPO4 IEA Sus scrofa 77636 R-BTA-162683 https://reactome.org/PathwayBrowser/#/R-BTA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Bos taurus 77636 R-BTA-6810474 https://reactome.org/PathwayBrowser/#/R-BTA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Bos taurus 77636 R-BTA-75886 https://reactome.org/PathwayBrowser/#/R-BTA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Bos taurus 77636 R-BTA-75900 https://reactome.org/PathwayBrowser/#/R-BTA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Bos taurus 77636 R-CEL-162683 https://reactome.org/PathwayBrowser/#/R-CEL-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Caenorhabditis elegans 77636 R-CEL-549192 https://reactome.org/PathwayBrowser/#/R-CEL-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Caenorhabditis elegans 77636 R-CEL-6810474 https://reactome.org/PathwayBrowser/#/R-CEL-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Caenorhabditis elegans 77636 R-CEL-75886 https://reactome.org/PathwayBrowser/#/R-CEL-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Caenorhabditis elegans 77636 R-CEL-75900 https://reactome.org/PathwayBrowser/#/R-CEL-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Caenorhabditis elegans 77636 R-CFA-162683 https://reactome.org/PathwayBrowser/#/R-CFA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Canis familiaris 77636 R-CFA-549192 https://reactome.org/PathwayBrowser/#/R-CFA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Canis familiaris 77636 R-CFA-6810474 https://reactome.org/PathwayBrowser/#/R-CFA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Canis familiaris 77636 R-CFA-75886 https://reactome.org/PathwayBrowser/#/R-CFA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Canis familiaris 77636 R-CFA-75900 https://reactome.org/PathwayBrowser/#/R-CFA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Canis familiaris 77636 R-DDI-162683 https://reactome.org/PathwayBrowser/#/R-DDI-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Dictyostelium discoideum 77636 R-DDI-549192 https://reactome.org/PathwayBrowser/#/R-DDI-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Dictyostelium discoideum 77636 R-DDI-6810474 https://reactome.org/PathwayBrowser/#/R-DDI-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Dictyostelium discoideum 77636 R-DDI-75900 https://reactome.org/PathwayBrowser/#/R-DDI-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Dictyostelium discoideum 77636 R-DME-162683 https://reactome.org/PathwayBrowser/#/R-DME-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Drosophila melanogaster 77636 R-DME-549192 https://reactome.org/PathwayBrowser/#/R-DME-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Drosophila melanogaster 77636 R-DME-6810474 https://reactome.org/PathwayBrowser/#/R-DME-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Drosophila melanogaster 77636 R-DME-75886 https://reactome.org/PathwayBrowser/#/R-DME-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Drosophila melanogaster 77636 R-DME-75900 https://reactome.org/PathwayBrowser/#/R-DME-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Drosophila melanogaster 77636 R-DRE-549192 https://reactome.org/PathwayBrowser/#/R-DRE-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Danio rerio 77636 R-DRE-6810474 https://reactome.org/PathwayBrowser/#/R-DRE-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Danio rerio 77636 R-DRE-75900 https://reactome.org/PathwayBrowser/#/R-DRE-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Danio rerio 77636 R-GGA-162683 https://reactome.org/PathwayBrowser/#/R-GGA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Gallus gallus 77636 R-GGA-549192 https://reactome.org/PathwayBrowser/#/R-GGA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Gallus gallus 77636 R-GGA-6810474 https://reactome.org/PathwayBrowser/#/R-GGA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Gallus gallus 77636 R-GGA-75886 https://reactome.org/PathwayBrowser/#/R-GGA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Gallus gallus 77636 R-HSA-162683 https://reactome.org/PathwayBrowser/#/R-HSA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH TAS Homo sapiens 77636 R-HSA-549192 https://reactome.org/PathwayBrowser/#/R-HSA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] TAS Homo sapiens 77636 R-HSA-6810474 https://reactome.org/PathwayBrowser/#/R-HSA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT TAS Homo sapiens 77636 R-HSA-75886 https://reactome.org/PathwayBrowser/#/R-HSA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] TAS Homo sapiens 77636 R-HSA-75900 https://reactome.org/PathwayBrowser/#/R-HSA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] TAS Homo sapiens 77636 R-MMU-162683 https://reactome.org/PathwayBrowser/#/R-MMU-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Mus musculus 77636 R-MMU-549192 https://reactome.org/PathwayBrowser/#/R-MMU-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Mus musculus 77636 R-MMU-6810474 https://reactome.org/PathwayBrowser/#/R-MMU-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Mus musculus 77636 R-MMU-75886 https://reactome.org/PathwayBrowser/#/R-MMU-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Mus musculus 77636 R-MMU-75900 https://reactome.org/PathwayBrowser/#/R-MMU-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Mus musculus 77636 R-PFA-162683 https://reactome.org/PathwayBrowser/#/R-PFA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Plasmodium falciparum 77636 R-PFA-75900 https://reactome.org/PathwayBrowser/#/R-PFA-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Plasmodium falciparum 77636 R-RNO-162683 https://reactome.org/PathwayBrowser/#/R-RNO-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Rattus norvegicus 77636 R-RNO-549192 https://reactome.org/PathwayBrowser/#/R-RNO-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Rattus norvegicus 77636 R-RNO-6810474 https://reactome.org/PathwayBrowser/#/R-RNO-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Rattus norvegicus 77636 R-RNO-75886 https://reactome.org/PathwayBrowser/#/R-RNO-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Rattus norvegicus 77636 R-RNO-75900 https://reactome.org/PathwayBrowser/#/R-RNO-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Rattus norvegicus 77636 R-SCE-162683 https://reactome.org/PathwayBrowser/#/R-SCE-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Saccharomyces cerevisiae 77636 R-SCE-549192 https://reactome.org/PathwayBrowser/#/R-SCE-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Saccharomyces cerevisiae 77636 R-SPO-162683 https://reactome.org/PathwayBrowser/#/R-SPO-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Schizosaccharomyces pombe 77636 R-SPO-549192 https://reactome.org/PathwayBrowser/#/R-SPO-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Schizosaccharomyces pombe 77636 R-SSC-162683 https://reactome.org/PathwayBrowser/#/R-SSC-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Sus scrofa 77636 R-SSC-549192 https://reactome.org/PathwayBrowser/#/R-SSC-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Sus scrofa 77636 R-SSC-6810474 https://reactome.org/PathwayBrowser/#/R-SSC-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Sus scrofa 77636 R-SSC-75886 https://reactome.org/PathwayBrowser/#/R-SSC-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Sus scrofa 77636 R-SSC-75900 https://reactome.org/PathwayBrowser/#/R-SSC-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Sus scrofa 77636 R-XTR-162683 https://reactome.org/PathwayBrowser/#/R-XTR-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Xenopus tropicalis 77636 R-XTR-549192 https://reactome.org/PathwayBrowser/#/R-XTR-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Xenopus tropicalis 77636 R-XTR-6810474 https://reactome.org/PathwayBrowser/#/R-XTR-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Xenopus tropicalis 77636 R-XTR-75886 https://reactome.org/PathwayBrowser/#/R-XTR-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Xenopus tropicalis 77636 R-XTR-75900 https://reactome.org/PathwayBrowser/#/R-XTR-75900 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] IEA Xenopus tropicalis 77657 R-BTA-73805 https://reactome.org/PathwayBrowser/#/R-BTA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Bos taurus 77657 R-BTA-73806 https://reactome.org/PathwayBrowser/#/R-BTA-73806 AIR + CO2 => CAIR IEA Bos taurus 77657 R-CEL-73805 https://reactome.org/PathwayBrowser/#/R-CEL-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Caenorhabditis elegans 77657 R-CEL-73806 https://reactome.org/PathwayBrowser/#/R-CEL-73806 AIR + CO2 => CAIR IEA Caenorhabditis elegans 77657 R-CFA-73805 https://reactome.org/PathwayBrowser/#/R-CFA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Canis familiaris 77657 R-CFA-73806 https://reactome.org/PathwayBrowser/#/R-CFA-73806 AIR + CO2 => CAIR IEA Canis familiaris 77657 R-DME-73805 https://reactome.org/PathwayBrowser/#/R-DME-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Drosophila melanogaster 77657 R-DME-73806 https://reactome.org/PathwayBrowser/#/R-DME-73806 AIR + CO2 => CAIR IEA Drosophila melanogaster 77657 R-DRE-73805 https://reactome.org/PathwayBrowser/#/R-DRE-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Danio rerio 77657 R-DRE-73806 https://reactome.org/PathwayBrowser/#/R-DRE-73806 AIR + CO2 => CAIR IEA Danio rerio 77657 R-GGA-419214 https://reactome.org/PathwayBrowser/#/R-GGA-419214 5'-phosphoribosyl-5-aminoimidazole (AIR) + CO2 <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) TAS Gallus gallus 77657 R-GGA-419223 https://reactome.org/PathwayBrowser/#/R-GGA-419223 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 77657 R-GGA-73805 https://reactome.org/PathwayBrowser/#/R-GGA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Gallus gallus 77657 R-GGA-73806 https://reactome.org/PathwayBrowser/#/R-GGA-73806 AIR + CO2 => CAIR IEA Gallus gallus 77657 R-HSA-73805 https://reactome.org/PathwayBrowser/#/R-HSA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi TAS Homo sapiens 77657 R-HSA-73806 https://reactome.org/PathwayBrowser/#/R-HSA-73806 AIR + CO2 => CAIR TAS Homo sapiens 77657 R-MMU-73805 https://reactome.org/PathwayBrowser/#/R-MMU-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Mus musculus 77657 R-MMU-73806 https://reactome.org/PathwayBrowser/#/R-MMU-73806 AIR + CO2 => CAIR IEA Mus musculus 77657 R-RNO-73805 https://reactome.org/PathwayBrowser/#/R-RNO-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Rattus norvegicus 77657 R-RNO-73806 https://reactome.org/PathwayBrowser/#/R-RNO-73806 AIR + CO2 => CAIR IEA Rattus norvegicus 77657 R-SSC-73805 https://reactome.org/PathwayBrowser/#/R-SSC-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Sus scrofa 77657 R-SSC-73806 https://reactome.org/PathwayBrowser/#/R-SSC-73806 AIR + CO2 => CAIR IEA Sus scrofa 77657 R-XTR-73805 https://reactome.org/PathwayBrowser/#/R-XTR-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Xenopus tropicalis 77657 R-XTR-73806 https://reactome.org/PathwayBrowser/#/R-XTR-73806 AIR + CO2 => CAIR IEA Xenopus tropicalis 7772 R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 7772 R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 7772 R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 7772 R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 7772 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 7772 R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 7772 R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 7772 R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 7772 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 77802 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 77802 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 77802 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 77802 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 77802 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 77802 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 77802 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 77802 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 77802 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 77802 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 77802 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 77802 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 77802 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 77802 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 77802 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 77803 R-BTA-71218 https://reactome.org/PathwayBrowser/#/R-BTA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Bos taurus 77803 R-CEL-71218 https://reactome.org/PathwayBrowser/#/R-CEL-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Caenorhabditis elegans 77803 R-CFA-71218 https://reactome.org/PathwayBrowser/#/R-CFA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Canis familiaris 77803 R-DDI-71218 https://reactome.org/PathwayBrowser/#/R-DDI-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Dictyostelium discoideum 77803 R-DRE-71218 https://reactome.org/PathwayBrowser/#/R-DRE-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Danio rerio 77803 R-GGA-71218 https://reactome.org/PathwayBrowser/#/R-GGA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Gallus gallus 77803 R-HSA-197187 https://reactome.org/PathwayBrowser/#/R-HSA-197187 ACS transforms to QUIN non-enzymatically TAS Homo sapiens 77803 R-HSA-71218 https://reactome.org/PathwayBrowser/#/R-HSA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde TAS Homo sapiens 77803 R-HSA-71223 https://reactome.org/PathwayBrowser/#/R-HSA-71223 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 IEA Homo sapiens 77803 R-MMU-71218 https://reactome.org/PathwayBrowser/#/R-MMU-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Mus musculus 77803 R-RNO-71218 https://reactome.org/PathwayBrowser/#/R-RNO-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Rattus norvegicus 77803 R-RNO-71234 https://reactome.org/PathwayBrowser/#/R-RNO-71234 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 [rat] TAS Rattus norvegicus 77803 R-SCE-71218 https://reactome.org/PathwayBrowser/#/R-SCE-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Saccharomyces cerevisiae 77803 R-SSC-71218 https://reactome.org/PathwayBrowser/#/R-SSC-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Sus scrofa 77803 R-XTR-71218 https://reactome.org/PathwayBrowser/#/R-XTR-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Xenopus tropicalis 77859 R-FCA-164926 https://reactome.org/PathwayBrowser/#/R-FCA-164926 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ TAS Felis catus 77859 R-HSA-71239 https://reactome.org/PathwayBrowser/#/R-HSA-71239 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ IEA Homo sapiens 7789 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 7789 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 7789 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 7789 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 7789 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 7789 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 7789 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 7789 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 7789 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 7789 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 77896 R-BTA-2395849 https://reactome.org/PathwayBrowser/#/R-BTA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 77896 R-BTA-2395869 https://reactome.org/PathwayBrowser/#/R-BTA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 77896 R-CFA-2395849 https://reactome.org/PathwayBrowser/#/R-CFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 77896 R-CFA-2395869 https://reactome.org/PathwayBrowser/#/R-CFA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 77896 R-DRE-2395849 https://reactome.org/PathwayBrowser/#/R-DRE-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Danio rerio 77896 R-GGA-2395849 https://reactome.org/PathwayBrowser/#/R-GGA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 77896 R-GGA-2395869 https://reactome.org/PathwayBrowser/#/R-GGA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 77896 R-HSA-2395849 https://reactome.org/PathwayBrowser/#/R-HSA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 77896 R-HSA-2395869 https://reactome.org/PathwayBrowser/#/R-HSA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 77896 R-MMU-2395849 https://reactome.org/PathwayBrowser/#/R-MMU-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 77896 R-MMU-2395869 https://reactome.org/PathwayBrowser/#/R-MMU-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 77896 R-PFA-2395849 https://reactome.org/PathwayBrowser/#/R-PFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Plasmodium falciparum 77896 R-RNO-2395849 https://reactome.org/PathwayBrowser/#/R-RNO-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 77896 R-RNO-2395869 https://reactome.org/PathwayBrowser/#/R-RNO-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 77896 R-SSC-2395849 https://reactome.org/PathwayBrowser/#/R-SSC-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 77896 R-SSC-2395869 https://reactome.org/PathwayBrowser/#/R-SSC-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 77896 R-XTR-2395849 https://reactome.org/PathwayBrowser/#/R-XTR-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 77896 R-XTR-2395869 https://reactome.org/PathwayBrowser/#/R-XTR-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 77897 R-BTA-2395818 https://reactome.org/PathwayBrowser/#/R-BTA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Bos taurus 77897 R-CFA-2395818 https://reactome.org/PathwayBrowser/#/R-CFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Canis familiaris 77897 R-DRE-2395818 https://reactome.org/PathwayBrowser/#/R-DRE-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Danio rerio 77897 R-GGA-2395818 https://reactome.org/PathwayBrowser/#/R-GGA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Gallus gallus 77897 R-HSA-2395818 https://reactome.org/PathwayBrowser/#/R-HSA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP TAS Homo sapiens 77897 R-MMU-2395818 https://reactome.org/PathwayBrowser/#/R-MMU-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Mus musculus 77897 R-PFA-2395818 https://reactome.org/PathwayBrowser/#/R-PFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Plasmodium falciparum 77897 R-RNO-2395818 https://reactome.org/PathwayBrowser/#/R-RNO-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Rattus norvegicus 77897 R-SSC-2395818 https://reactome.org/PathwayBrowser/#/R-SSC-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Sus scrofa 77897 R-XTR-2395818 https://reactome.org/PathwayBrowser/#/R-XTR-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Xenopus tropicalis 7794 R-BTA-8878787 https://reactome.org/PathwayBrowser/#/R-BTA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Bos taurus 7794 R-CFA-8878787 https://reactome.org/PathwayBrowser/#/R-CFA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Canis familiaris 7794 R-DME-8878787 https://reactome.org/PathwayBrowser/#/R-DME-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Drosophila melanogaster 7794 R-DRE-8878787 https://reactome.org/PathwayBrowser/#/R-DRE-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Danio rerio 7794 R-GGA-8878787 https://reactome.org/PathwayBrowser/#/R-GGA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Gallus gallus 7794 R-HSA-8878787 https://reactome.org/PathwayBrowser/#/R-HSA-8878787 ALPI dimer hydrolyses phosphate monoesters TAS Homo sapiens 7794 R-MMU-8878787 https://reactome.org/PathwayBrowser/#/R-MMU-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Mus musculus 7794 R-RNO-8878787 https://reactome.org/PathwayBrowser/#/R-RNO-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Rattus norvegicus 7794 R-SSC-8878787 https://reactome.org/PathwayBrowser/#/R-SSC-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Sus scrofa 7794 R-XTR-8878787 https://reactome.org/PathwayBrowser/#/R-XTR-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Xenopus tropicalis 77983 R-BTA-1855157 https://reactome.org/PathwayBrowser/#/R-BTA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Bos taurus 77983 R-BTA-1855165 https://reactome.org/PathwayBrowser/#/R-BTA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 77983 R-BTA-1855182 https://reactome.org/PathwayBrowser/#/R-BTA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Bos taurus 77983 R-BTA-1855194 https://reactome.org/PathwayBrowser/#/R-BTA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Bos taurus 77983 R-BTA-2023973 https://reactome.org/PathwayBrowser/#/R-BTA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 77983 R-CEL-1855157 https://reactome.org/PathwayBrowser/#/R-CEL-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Caenorhabditis elegans 77983 R-CEL-1855165 https://reactome.org/PathwayBrowser/#/R-CEL-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 77983 R-CEL-1855182 https://reactome.org/PathwayBrowser/#/R-CEL-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Caenorhabditis elegans 77983 R-CEL-1855194 https://reactome.org/PathwayBrowser/#/R-CEL-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Caenorhabditis elegans 77983 R-CEL-2023973 https://reactome.org/PathwayBrowser/#/R-CEL-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 77983 R-CFA-1855157 https://reactome.org/PathwayBrowser/#/R-CFA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Canis familiaris 77983 R-CFA-1855165 https://reactome.org/PathwayBrowser/#/R-CFA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 77983 R-CFA-1855182 https://reactome.org/PathwayBrowser/#/R-CFA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Canis familiaris 77983 R-CFA-1855194 https://reactome.org/PathwayBrowser/#/R-CFA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Canis familiaris 77983 R-CFA-2023973 https://reactome.org/PathwayBrowser/#/R-CFA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 77983 R-DDI-1855157 https://reactome.org/PathwayBrowser/#/R-DDI-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Dictyostelium discoideum 77983 R-DDI-1855165 https://reactome.org/PathwayBrowser/#/R-DDI-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 77983 R-DDI-1855194 https://reactome.org/PathwayBrowser/#/R-DDI-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Dictyostelium discoideum 77983 R-DDI-2023973 https://reactome.org/PathwayBrowser/#/R-DDI-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 77983 R-DME-1855157 https://reactome.org/PathwayBrowser/#/R-DME-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Drosophila melanogaster 77983 R-DME-1855165 https://reactome.org/PathwayBrowser/#/R-DME-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 77983 R-DME-1855182 https://reactome.org/PathwayBrowser/#/R-DME-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Drosophila melanogaster 77983 R-DME-1855194 https://reactome.org/PathwayBrowser/#/R-DME-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Drosophila melanogaster 77983 R-DME-2023973 https://reactome.org/PathwayBrowser/#/R-DME-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 77983 R-DRE-1855157 https://reactome.org/PathwayBrowser/#/R-DRE-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Danio rerio 77983 R-DRE-1855165 https://reactome.org/PathwayBrowser/#/R-DRE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 77983 R-DRE-1855194 https://reactome.org/PathwayBrowser/#/R-DRE-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Danio rerio 77983 R-DRE-2023973 https://reactome.org/PathwayBrowser/#/R-DRE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 77983 R-GGA-1855157 https://reactome.org/PathwayBrowser/#/R-GGA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Gallus gallus 77983 R-GGA-1855165 https://reactome.org/PathwayBrowser/#/R-GGA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 77983 R-GGA-1855182 https://reactome.org/PathwayBrowser/#/R-GGA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Gallus gallus 77983 R-GGA-1855194 https://reactome.org/PathwayBrowser/#/R-GGA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Gallus gallus 77983 R-GGA-2023973 https://reactome.org/PathwayBrowser/#/R-GGA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 77983 R-HSA-1855157 https://reactome.org/PathwayBrowser/#/R-HSA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus TAS Homo sapiens 77983 R-HSA-1855165 https://reactome.org/PathwayBrowser/#/R-HSA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 77983 R-HSA-1855182 https://reactome.org/PathwayBrowser/#/R-HSA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol TAS Homo sapiens 77983 R-HSA-1855194 https://reactome.org/PathwayBrowser/#/R-HSA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol TAS Homo sapiens 77983 R-HSA-1855220 https://reactome.org/PathwayBrowser/#/R-HSA-1855220 (PP)2-IP4 transports from the nucleus to the cytosol TAS Homo sapiens 77983 R-HSA-2023973 https://reactome.org/PathwayBrowser/#/R-HSA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 77983 R-MMU-1855157 https://reactome.org/PathwayBrowser/#/R-MMU-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Mus musculus 77983 R-MMU-1855165 https://reactome.org/PathwayBrowser/#/R-MMU-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 77983 R-MMU-1855182 https://reactome.org/PathwayBrowser/#/R-MMU-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Mus musculus 77983 R-MMU-1855194 https://reactome.org/PathwayBrowser/#/R-MMU-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Mus musculus 77983 R-MMU-2023973 https://reactome.org/PathwayBrowser/#/R-MMU-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 77983 R-PFA-1855157 https://reactome.org/PathwayBrowser/#/R-PFA-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Plasmodium falciparum 77983 R-PFA-1855182 https://reactome.org/PathwayBrowser/#/R-PFA-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Plasmodium falciparum 77983 R-PFA-1855194 https://reactome.org/PathwayBrowser/#/R-PFA-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Plasmodium falciparum 77983 R-RNO-1855157 https://reactome.org/PathwayBrowser/#/R-RNO-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Rattus norvegicus 77983 R-RNO-1855165 https://reactome.org/PathwayBrowser/#/R-RNO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 77983 R-RNO-1855182 https://reactome.org/PathwayBrowser/#/R-RNO-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Rattus norvegicus 77983 R-RNO-1855194 https://reactome.org/PathwayBrowser/#/R-RNO-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Rattus norvegicus 77983 R-RNO-2023973 https://reactome.org/PathwayBrowser/#/R-RNO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 77983 R-SCE-1855157 https://reactome.org/PathwayBrowser/#/R-SCE-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Saccharomyces cerevisiae 77983 R-SCE-1855165 https://reactome.org/PathwayBrowser/#/R-SCE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 77983 R-SCE-1855182 https://reactome.org/PathwayBrowser/#/R-SCE-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Saccharomyces cerevisiae 77983 R-SCE-1855194 https://reactome.org/PathwayBrowser/#/R-SCE-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Saccharomyces cerevisiae 77983 R-SCE-2023973 https://reactome.org/PathwayBrowser/#/R-SCE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 77983 R-SPO-1855157 https://reactome.org/PathwayBrowser/#/R-SPO-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Schizosaccharomyces pombe 77983 R-SPO-1855165 https://reactome.org/PathwayBrowser/#/R-SPO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 77983 R-SPO-1855182 https://reactome.org/PathwayBrowser/#/R-SPO-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Schizosaccharomyces pombe 77983 R-SPO-1855194 https://reactome.org/PathwayBrowser/#/R-SPO-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Schizosaccharomyces pombe 77983 R-SPO-2023973 https://reactome.org/PathwayBrowser/#/R-SPO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 77983 R-SSC-1855157 https://reactome.org/PathwayBrowser/#/R-SSC-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Sus scrofa 77983 R-SSC-1855165 https://reactome.org/PathwayBrowser/#/R-SSC-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 77983 R-SSC-1855182 https://reactome.org/PathwayBrowser/#/R-SSC-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Sus scrofa 77983 R-SSC-1855194 https://reactome.org/PathwayBrowser/#/R-SSC-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Sus scrofa 77983 R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 77983 R-XTR-1855157 https://reactome.org/PathwayBrowser/#/R-XTR-1855157 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus IEA Xenopus tropicalis 77983 R-XTR-1855165 https://reactome.org/PathwayBrowser/#/R-XTR-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 77983 R-XTR-1855182 https://reactome.org/PathwayBrowser/#/R-XTR-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Xenopus tropicalis 77983 R-XTR-1855194 https://reactome.org/PathwayBrowser/#/R-XTR-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Xenopus tropicalis 77983 R-XTR-2023973 https://reactome.org/PathwayBrowser/#/R-XTR-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 78030 R-HSA-5340560 https://reactome.org/PathwayBrowser/#/R-HSA-5340560 PORCN-inhibitor LGK974 prevents WNT ligand palmitoyltation and secretion TAS Homo sapiens 78236 R-BTA-9753944 https://reactome.org/PathwayBrowser/#/R-BTA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Bos taurus 78236 R-CEL-9753944 https://reactome.org/PathwayBrowser/#/R-CEL-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Caenorhabditis elegans 78236 R-CFA-9753944 https://reactome.org/PathwayBrowser/#/R-CFA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Canis familiaris 78236 R-DDI-9753944 https://reactome.org/PathwayBrowser/#/R-DDI-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Dictyostelium discoideum 78236 R-DME-9753944 https://reactome.org/PathwayBrowser/#/R-DME-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Drosophila melanogaster 78236 R-GGA-9753944 https://reactome.org/PathwayBrowser/#/R-GGA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Gallus gallus 78236 R-HSA-9753944 https://reactome.org/PathwayBrowser/#/R-HSA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys TAS Homo sapiens 78236 R-MMU-9753944 https://reactome.org/PathwayBrowser/#/R-MMU-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Mus musculus 78236 R-RNO-9753944 https://reactome.org/PathwayBrowser/#/R-RNO-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Rattus norvegicus 78236 R-SSC-9753944 https://reactome.org/PathwayBrowser/#/R-SSC-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Sus scrofa 78236 R-XTR-9753944 https://reactome.org/PathwayBrowser/#/R-XTR-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Xenopus tropicalis 78273 R-BTA-5696101 https://reactome.org/PathwayBrowser/#/R-BTA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Bos taurus 78273 R-CEL-5696101 https://reactome.org/PathwayBrowser/#/R-CEL-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Caenorhabditis elegans 78273 R-CFA-5696101 https://reactome.org/PathwayBrowser/#/R-CFA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Canis familiaris 78273 R-DDI-5696101 https://reactome.org/PathwayBrowser/#/R-DDI-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Dictyostelium discoideum 78273 R-DRE-5696101 https://reactome.org/PathwayBrowser/#/R-DRE-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Danio rerio 78273 R-GGA-5696101 https://reactome.org/PathwayBrowser/#/R-GGA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Gallus gallus 78273 R-HSA-5696101 https://reactome.org/PathwayBrowser/#/R-HSA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA TAS Homo sapiens 78273 R-MMU-5696101 https://reactome.org/PathwayBrowser/#/R-MMU-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Mus musculus 78273 R-RNO-5696101 https://reactome.org/PathwayBrowser/#/R-RNO-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Rattus norvegicus 78273 R-SSC-5696101 https://reactome.org/PathwayBrowser/#/R-SSC-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Sus scrofa 78273 R-XTR-5696101 https://reactome.org/PathwayBrowser/#/R-XTR-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Xenopus tropicalis 78277 R-BTA-159752 https://reactome.org/PathwayBrowser/#/R-BTA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Bos taurus 78277 R-BTA-159761 https://reactome.org/PathwayBrowser/#/R-BTA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Bos taurus 78277 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 78277 R-BTA-159795 https://reactome.org/PathwayBrowser/#/R-BTA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Bos taurus 78277 R-BTA-159803 https://reactome.org/PathwayBrowser/#/R-BTA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Bos taurus 78277 R-BTA-159819 https://reactome.org/PathwayBrowser/#/R-BTA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Bos taurus 78277 R-BTA-159826 https://reactome.org/PathwayBrowser/#/R-BTA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Bos taurus 78277 R-BTA-163820 https://reactome.org/PathwayBrowser/#/R-BTA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Bos taurus 78277 R-BTA-6806647 https://reactome.org/PathwayBrowser/#/R-BTA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 78277 R-BTA-6806674 https://reactome.org/PathwayBrowser/#/R-BTA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Bos taurus 78277 R-BTA-6807214 https://reactome.org/PathwayBrowser/#/R-BTA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Bos taurus 78277 R-CFA-159752 https://reactome.org/PathwayBrowser/#/R-CFA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Canis familiaris 78277 R-CFA-159761 https://reactome.org/PathwayBrowser/#/R-CFA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Canis familiaris 78277 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 78277 R-CFA-159795 https://reactome.org/PathwayBrowser/#/R-CFA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Canis familiaris 78277 R-CFA-159803 https://reactome.org/PathwayBrowser/#/R-CFA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Canis familiaris 78277 R-CFA-159819 https://reactome.org/PathwayBrowser/#/R-CFA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Canis familiaris 78277 R-CFA-159826 https://reactome.org/PathwayBrowser/#/R-CFA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Canis familiaris 78277 R-CFA-6806647 https://reactome.org/PathwayBrowser/#/R-CFA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 78277 R-CFA-6806674 https://reactome.org/PathwayBrowser/#/R-CFA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Canis familiaris 78277 R-CFA-6807214 https://reactome.org/PathwayBrowser/#/R-CFA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Canis familiaris 78277 R-DDI-6806674 https://reactome.org/PathwayBrowser/#/R-DDI-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Dictyostelium discoideum 78277 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 78277 R-DME-6806674 https://reactome.org/PathwayBrowser/#/R-DME-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 78277 R-DRE-6806647 https://reactome.org/PathwayBrowser/#/R-DRE-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Danio rerio 78277 R-DRE-6806674 https://reactome.org/PathwayBrowser/#/R-DRE-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Danio rerio 78277 R-GGA-6806647 https://reactome.org/PathwayBrowser/#/R-GGA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Gallus gallus 78277 R-GGA-6806674 https://reactome.org/PathwayBrowser/#/R-GGA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Gallus gallus 78277 R-HSA-159752 https://reactome.org/PathwayBrowser/#/R-HSA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) TAS Homo sapiens 78277 R-HSA-159761 https://reactome.org/PathwayBrowser/#/R-HSA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) TAS Homo sapiens 78277 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 78277 R-HSA-159795 https://reactome.org/PathwayBrowser/#/R-HSA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) TAS Homo sapiens 78277 R-HSA-159803 https://reactome.org/PathwayBrowser/#/R-HSA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) TAS Homo sapiens 78277 R-HSA-159819 https://reactome.org/PathwayBrowser/#/R-HSA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) TAS Homo sapiens 78277 R-HSA-159826 https://reactome.org/PathwayBrowser/#/R-HSA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) TAS Homo sapiens 78277 R-HSA-163810 https://reactome.org/PathwayBrowser/#/R-HSA-163810 GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6) IEA Homo sapiens 78277 R-HSA-163820 https://reactome.org/PathwayBrowser/#/R-HSA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) TAS Homo sapiens 78277 R-HSA-6806647 https://reactome.org/PathwayBrowser/#/R-HSA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 78277 R-HSA-6806674 https://reactome.org/PathwayBrowser/#/R-HSA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) TAS Homo sapiens 78277 R-HSA-6807214 https://reactome.org/PathwayBrowser/#/R-HSA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) TAS Homo sapiens 78277 R-HSA-9673231 https://reactome.org/PathwayBrowser/#/R-HSA-9673231 GGCX does not gamma-carboxylate 3D-F9(29-461) (pro-factor IX) TAS Homo sapiens 78277 R-MMU-159752 https://reactome.org/PathwayBrowser/#/R-MMU-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Mus musculus 78277 R-MMU-159761 https://reactome.org/PathwayBrowser/#/R-MMU-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Mus musculus 78277 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 78277 R-MMU-159795 https://reactome.org/PathwayBrowser/#/R-MMU-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Mus musculus 78277 R-MMU-159803 https://reactome.org/PathwayBrowser/#/R-MMU-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Mus musculus 78277 R-MMU-159819 https://reactome.org/PathwayBrowser/#/R-MMU-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Mus musculus 78277 R-MMU-159826 https://reactome.org/PathwayBrowser/#/R-MMU-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Mus musculus 78277 R-MMU-163820 https://reactome.org/PathwayBrowser/#/R-MMU-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Mus musculus 78277 R-MMU-6806647 https://reactome.org/PathwayBrowser/#/R-MMU-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 78277 R-MMU-6806674 https://reactome.org/PathwayBrowser/#/R-MMU-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Mus musculus 78277 R-MMU-6807214 https://reactome.org/PathwayBrowser/#/R-MMU-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Mus musculus 78277 R-RNO-159752 https://reactome.org/PathwayBrowser/#/R-RNO-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Rattus norvegicus 78277 R-RNO-159761 https://reactome.org/PathwayBrowser/#/R-RNO-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Rattus norvegicus 78277 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 78277 R-RNO-159795 https://reactome.org/PathwayBrowser/#/R-RNO-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Rattus norvegicus 78277 R-RNO-159803 https://reactome.org/PathwayBrowser/#/R-RNO-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Rattus norvegicus 78277 R-RNO-159819 https://reactome.org/PathwayBrowser/#/R-RNO-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Rattus norvegicus 78277 R-RNO-159826 https://reactome.org/PathwayBrowser/#/R-RNO-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Rattus norvegicus 78277 R-RNO-163820 https://reactome.org/PathwayBrowser/#/R-RNO-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Rattus norvegicus 78277 R-RNO-6806647 https://reactome.org/PathwayBrowser/#/R-RNO-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 78277 R-RNO-6806674 https://reactome.org/PathwayBrowser/#/R-RNO-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 78277 R-RNO-6807214 https://reactome.org/PathwayBrowser/#/R-RNO-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Rattus norvegicus 78277 R-SSC-159752 https://reactome.org/PathwayBrowser/#/R-SSC-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Sus scrofa 78277 R-SSC-159761 https://reactome.org/PathwayBrowser/#/R-SSC-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Sus scrofa 78277 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 78277 R-SSC-159795 https://reactome.org/PathwayBrowser/#/R-SSC-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Sus scrofa 78277 R-SSC-159803 https://reactome.org/PathwayBrowser/#/R-SSC-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Sus scrofa 78277 R-SSC-159819 https://reactome.org/PathwayBrowser/#/R-SSC-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Sus scrofa 78277 R-SSC-159826 https://reactome.org/PathwayBrowser/#/R-SSC-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Sus scrofa 78277 R-SSC-6806647 https://reactome.org/PathwayBrowser/#/R-SSC-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 78277 R-SSC-6806674 https://reactome.org/PathwayBrowser/#/R-SSC-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Sus scrofa 78277 R-SSC-6807214 https://reactome.org/PathwayBrowser/#/R-SSC-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Sus scrofa 78277 R-XTR-159752 https://reactome.org/PathwayBrowser/#/R-XTR-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Xenopus tropicalis 78277 R-XTR-159761 https://reactome.org/PathwayBrowser/#/R-XTR-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Xenopus tropicalis 78277 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 78277 R-XTR-159795 https://reactome.org/PathwayBrowser/#/R-XTR-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Xenopus tropicalis 78277 R-XTR-159803 https://reactome.org/PathwayBrowser/#/R-XTR-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Xenopus tropicalis 78277 R-XTR-159819 https://reactome.org/PathwayBrowser/#/R-XTR-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Xenopus tropicalis 78277 R-XTR-159826 https://reactome.org/PathwayBrowser/#/R-XTR-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Xenopus tropicalis 78277 R-XTR-163820 https://reactome.org/PathwayBrowser/#/R-XTR-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Xenopus tropicalis 78277 R-XTR-6806647 https://reactome.org/PathwayBrowser/#/R-XTR-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 78277 R-XTR-6806674 https://reactome.org/PathwayBrowser/#/R-XTR-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 78277 R-XTR-6807214 https://reactome.org/PathwayBrowser/#/R-XTR-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Xenopus tropicalis 78346 R-BTA-111215 https://reactome.org/PathwayBrowser/#/R-BTA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Bos taurus 78346 R-BTA-163741 https://reactome.org/PathwayBrowser/#/R-BTA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Bos taurus 78346 R-BTA-177784 https://reactome.org/PathwayBrowser/#/R-BTA-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Bos taurus 78346 R-BTA-2393939 https://reactome.org/PathwayBrowser/#/R-BTA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 78346 R-BTA-2393954 https://reactome.org/PathwayBrowser/#/R-BTA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 78346 R-BTA-5696049 https://reactome.org/PathwayBrowser/#/R-BTA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 78346 R-BTA-6787329 https://reactome.org/PathwayBrowser/#/R-BTA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Bos taurus 78346 R-BTA-71306 https://reactome.org/PathwayBrowser/#/R-BTA-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Bos taurus 78346 R-BTA-71324 https://reactome.org/PathwayBrowser/#/R-BTA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Bos taurus 78346 R-BTA-73580 https://reactome.org/PathwayBrowser/#/R-BTA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Bos taurus 78346 R-BTA-8955844 https://reactome.org/PathwayBrowser/#/R-BTA-8955844 RBKS phosphorylates ribose to R5P IEA Bos taurus 78346 R-CEL-163741 https://reactome.org/PathwayBrowser/#/R-CEL-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Caenorhabditis elegans 78346 R-CEL-177784 https://reactome.org/PathwayBrowser/#/R-CEL-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Caenorhabditis elegans 78346 R-CEL-2393939 https://reactome.org/PathwayBrowser/#/R-CEL-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 78346 R-CEL-2393954 https://reactome.org/PathwayBrowser/#/R-CEL-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 78346 R-CEL-6787329 https://reactome.org/PathwayBrowser/#/R-CEL-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Caenorhabditis elegans 78346 R-CEL-71306 https://reactome.org/PathwayBrowser/#/R-CEL-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Caenorhabditis elegans 78346 R-CEL-71324 https://reactome.org/PathwayBrowser/#/R-CEL-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Caenorhabditis elegans 78346 R-CEL-8955844 https://reactome.org/PathwayBrowser/#/R-CEL-8955844 RBKS phosphorylates ribose to R5P IEA Caenorhabditis elegans 78346 R-CFA-111215 https://reactome.org/PathwayBrowser/#/R-CFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Canis familiaris 78346 R-CFA-163741 https://reactome.org/PathwayBrowser/#/R-CFA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Canis familiaris 78346 R-CFA-177784 https://reactome.org/PathwayBrowser/#/R-CFA-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Canis familiaris 78346 R-CFA-2393939 https://reactome.org/PathwayBrowser/#/R-CFA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 78346 R-CFA-2393954 https://reactome.org/PathwayBrowser/#/R-CFA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 78346 R-CFA-5696049 https://reactome.org/PathwayBrowser/#/R-CFA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 78346 R-CFA-6787329 https://reactome.org/PathwayBrowser/#/R-CFA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Canis familiaris 78346 R-CFA-71306 https://reactome.org/PathwayBrowser/#/R-CFA-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Canis familiaris 78346 R-CFA-71324 https://reactome.org/PathwayBrowser/#/R-CFA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Canis familiaris 78346 R-CFA-73580 https://reactome.org/PathwayBrowser/#/R-CFA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Canis familiaris 78346 R-CFA-8955844 https://reactome.org/PathwayBrowser/#/R-CFA-8955844 RBKS phosphorylates ribose to R5P IEA Canis familiaris 78346 R-DDI-111215 https://reactome.org/PathwayBrowser/#/R-DDI-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Dictyostelium discoideum 78346 R-DDI-177784 https://reactome.org/PathwayBrowser/#/R-DDI-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Dictyostelium discoideum 78346 R-DDI-2393939 https://reactome.org/PathwayBrowser/#/R-DDI-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Dictyostelium discoideum 78346 R-DDI-6787329 https://reactome.org/PathwayBrowser/#/R-DDI-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Dictyostelium discoideum 78346 R-DDI-71306 https://reactome.org/PathwayBrowser/#/R-DDI-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Dictyostelium discoideum 78346 R-DDI-73580 https://reactome.org/PathwayBrowser/#/R-DDI-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Dictyostelium discoideum 78346 R-DDI-8955844 https://reactome.org/PathwayBrowser/#/R-DDI-8955844 RBKS phosphorylates ribose to R5P IEA Dictyostelium discoideum 78346 R-DME-163741 https://reactome.org/PathwayBrowser/#/R-DME-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Drosophila melanogaster 78346 R-DME-177784 https://reactome.org/PathwayBrowser/#/R-DME-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Drosophila melanogaster 78346 R-DME-2393954 https://reactome.org/PathwayBrowser/#/R-DME-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Drosophila melanogaster 78346 R-DME-6787329 https://reactome.org/PathwayBrowser/#/R-DME-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Drosophila melanogaster 78346 R-DME-71306 https://reactome.org/PathwayBrowser/#/R-DME-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Drosophila melanogaster 78346 R-DME-71324 https://reactome.org/PathwayBrowser/#/R-DME-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Drosophila melanogaster 78346 R-DME-8955844 https://reactome.org/PathwayBrowser/#/R-DME-8955844 RBKS phosphorylates ribose to R5P IEA Drosophila melanogaster 78346 R-DRE-111215 https://reactome.org/PathwayBrowser/#/R-DRE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Danio rerio 78346 R-DRE-177784 https://reactome.org/PathwayBrowser/#/R-DRE-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Danio rerio 78346 R-DRE-2393939 https://reactome.org/PathwayBrowser/#/R-DRE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 78346 R-DRE-5696049 https://reactome.org/PathwayBrowser/#/R-DRE-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 78346 R-DRE-6787329 https://reactome.org/PathwayBrowser/#/R-DRE-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Danio rerio 78346 R-DRE-71306 https://reactome.org/PathwayBrowser/#/R-DRE-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Danio rerio 78346 R-DRE-73580 https://reactome.org/PathwayBrowser/#/R-DRE-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Danio rerio 78346 R-DRE-8955844 https://reactome.org/PathwayBrowser/#/R-DRE-8955844 RBKS phosphorylates ribose to R5P IEA Danio rerio 78346 R-GGA-111215 https://reactome.org/PathwayBrowser/#/R-GGA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Gallus gallus 78346 R-GGA-163741 https://reactome.org/PathwayBrowser/#/R-GGA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Gallus gallus 78346 R-GGA-177784 https://reactome.org/PathwayBrowser/#/R-GGA-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Gallus gallus 78346 R-GGA-2393939 https://reactome.org/PathwayBrowser/#/R-GGA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 78346 R-GGA-2393954 https://reactome.org/PathwayBrowser/#/R-GGA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 78346 R-GGA-5696049 https://reactome.org/PathwayBrowser/#/R-GGA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 78346 R-GGA-6787329 https://reactome.org/PathwayBrowser/#/R-GGA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Gallus gallus 78346 R-GGA-71306 https://reactome.org/PathwayBrowser/#/R-GGA-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Gallus gallus 78346 R-GGA-71324 https://reactome.org/PathwayBrowser/#/R-GGA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus 78346 R-GGA-73580 https://reactome.org/PathwayBrowser/#/R-GGA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Gallus gallus 78346 R-GGA-8955844 https://reactome.org/PathwayBrowser/#/R-GGA-8955844 RBKS phosphorylates ribose to R5P IEA Gallus gallus 78346 R-HSA-111215 https://reactome.org/PathwayBrowser/#/R-HSA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate TAS Homo sapiens 78346 R-HSA-163741 https://reactome.org/PathwayBrowser/#/R-HSA-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate TAS Homo sapiens 78346 R-HSA-177784 https://reactome.org/PathwayBrowser/#/R-HSA-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate TAS Homo sapiens 78346 R-HSA-2393939 https://reactome.org/PathwayBrowser/#/R-HSA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 78346 R-HSA-2393954 https://reactome.org/PathwayBrowser/#/R-HSA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 78346 R-HSA-5660015 https://reactome.org/PathwayBrowser/#/R-HSA-5660015 Defective RPIA does not isomerize R5P to RU5P TAS Homo sapiens 78346 R-HSA-5696049 https://reactome.org/PathwayBrowser/#/R-HSA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 78346 R-HSA-6787329 https://reactome.org/PathwayBrowser/#/R-HSA-6787329 PGM2:Mg2+ isomerises R1P to R5P TAS Homo sapiens 78346 R-HSA-71306 https://reactome.org/PathwayBrowser/#/R-HSA-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate TAS Homo sapiens 78346 R-HSA-71324 https://reactome.org/PathwayBrowser/#/R-HSA-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate TAS Homo sapiens 78346 R-HSA-73580 https://reactome.org/PathwayBrowser/#/R-HSA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate TAS Homo sapiens 78346 R-HSA-8955844 https://reactome.org/PathwayBrowser/#/R-HSA-8955844 RBKS phosphorylates ribose to R5P TAS Homo sapiens 78346 R-MMU-111215 https://reactome.org/PathwayBrowser/#/R-MMU-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Mus musculus 78346 R-MMU-163741 https://reactome.org/PathwayBrowser/#/R-MMU-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Mus musculus 78346 R-MMU-177784 https://reactome.org/PathwayBrowser/#/R-MMU-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Mus musculus 78346 R-MMU-2393939 https://reactome.org/PathwayBrowser/#/R-MMU-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 78346 R-MMU-2393954 https://reactome.org/PathwayBrowser/#/R-MMU-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 78346 R-MMU-5696049 https://reactome.org/PathwayBrowser/#/R-MMU-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 78346 R-MMU-6787329 https://reactome.org/PathwayBrowser/#/R-MMU-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Mus musculus 78346 R-MMU-71306 https://reactome.org/PathwayBrowser/#/R-MMU-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Mus musculus 78346 R-MMU-71324 https://reactome.org/PathwayBrowser/#/R-MMU-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Mus musculus 78346 R-MMU-73580 https://reactome.org/PathwayBrowser/#/R-MMU-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Mus musculus 78346 R-MMU-8955844 https://reactome.org/PathwayBrowser/#/R-MMU-8955844 RBKS phosphorylates ribose to R5P IEA Mus musculus 78346 R-PFA-111215 https://reactome.org/PathwayBrowser/#/R-PFA-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Plasmodium falciparum 78346 R-PFA-6787329 https://reactome.org/PathwayBrowser/#/R-PFA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Plasmodium falciparum 78346 R-PFA-73580 https://reactome.org/PathwayBrowser/#/R-PFA-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Plasmodium falciparum 78346 R-RNO-111215 https://reactome.org/PathwayBrowser/#/R-RNO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Rattus norvegicus 78346 R-RNO-163741 https://reactome.org/PathwayBrowser/#/R-RNO-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Rattus norvegicus 78346 R-RNO-177784 https://reactome.org/PathwayBrowser/#/R-RNO-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Rattus norvegicus 78346 R-RNO-2393939 https://reactome.org/PathwayBrowser/#/R-RNO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 78346 R-RNO-2393954 https://reactome.org/PathwayBrowser/#/R-RNO-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 78346 R-RNO-5696049 https://reactome.org/PathwayBrowser/#/R-RNO-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 78346 R-RNO-6787329 https://reactome.org/PathwayBrowser/#/R-RNO-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Rattus norvegicus 78346 R-RNO-71306 https://reactome.org/PathwayBrowser/#/R-RNO-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Rattus norvegicus 78346 R-RNO-71324 https://reactome.org/PathwayBrowser/#/R-RNO-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Rattus norvegicus 78346 R-RNO-73580 https://reactome.org/PathwayBrowser/#/R-RNO-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Rattus norvegicus 78346 R-RNO-8955844 https://reactome.org/PathwayBrowser/#/R-RNO-8955844 RBKS phosphorylates ribose to R5P IEA Rattus norvegicus 78346 R-SCE-111215 https://reactome.org/PathwayBrowser/#/R-SCE-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Saccharomyces cerevisiae 78346 R-SCE-177784 https://reactome.org/PathwayBrowser/#/R-SCE-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Saccharomyces cerevisiae 78346 R-SCE-2393939 https://reactome.org/PathwayBrowser/#/R-SCE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Saccharomyces cerevisiae 78346 R-SCE-6787329 https://reactome.org/PathwayBrowser/#/R-SCE-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Saccharomyces cerevisiae 78346 R-SCE-71306 https://reactome.org/PathwayBrowser/#/R-SCE-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Saccharomyces cerevisiae 78346 R-SCE-73580 https://reactome.org/PathwayBrowser/#/R-SCE-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Saccharomyces cerevisiae 78346 R-SCE-8955844 https://reactome.org/PathwayBrowser/#/R-SCE-8955844 RBKS phosphorylates ribose to R5P IEA Saccharomyces cerevisiae 78346 R-SPO-111215 https://reactome.org/PathwayBrowser/#/R-SPO-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Schizosaccharomyces pombe 78346 R-SPO-177784 https://reactome.org/PathwayBrowser/#/R-SPO-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Schizosaccharomyces pombe 78346 R-SPO-2393939 https://reactome.org/PathwayBrowser/#/R-SPO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Schizosaccharomyces pombe 78346 R-SPO-6787329 https://reactome.org/PathwayBrowser/#/R-SPO-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Schizosaccharomyces pombe 78346 R-SPO-71306 https://reactome.org/PathwayBrowser/#/R-SPO-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Schizosaccharomyces pombe 78346 R-SPO-73580 https://reactome.org/PathwayBrowser/#/R-SPO-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Schizosaccharomyces pombe 78346 R-SPO-8955844 https://reactome.org/PathwayBrowser/#/R-SPO-8955844 RBKS phosphorylates ribose to R5P IEA Schizosaccharomyces pombe 78346 R-SSC-111215 https://reactome.org/PathwayBrowser/#/R-SSC-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Sus scrofa 78346 R-SSC-163741 https://reactome.org/PathwayBrowser/#/R-SSC-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Sus scrofa 78346 R-SSC-177784 https://reactome.org/PathwayBrowser/#/R-SSC-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Sus scrofa 78346 R-SSC-2393939 https://reactome.org/PathwayBrowser/#/R-SSC-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 78346 R-SSC-2393954 https://reactome.org/PathwayBrowser/#/R-SSC-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 78346 R-SSC-5696049 https://reactome.org/PathwayBrowser/#/R-SSC-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 78346 R-SSC-6787329 https://reactome.org/PathwayBrowser/#/R-SSC-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Sus scrofa 78346 R-SSC-71306 https://reactome.org/PathwayBrowser/#/R-SSC-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Sus scrofa 78346 R-SSC-71324 https://reactome.org/PathwayBrowser/#/R-SSC-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Sus scrofa 78346 R-SSC-73580 https://reactome.org/PathwayBrowser/#/R-SSC-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Sus scrofa 78346 R-SSC-8955844 https://reactome.org/PathwayBrowser/#/R-SSC-8955844 RBKS phosphorylates ribose to R5P IEA Sus scrofa 78346 R-XTR-111215 https://reactome.org/PathwayBrowser/#/R-XTR-111215 D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate IEA Xenopus tropicalis 78346 R-XTR-163741 https://reactome.org/PathwayBrowser/#/R-XTR-163741 D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate IEA Xenopus tropicalis 78346 R-XTR-177784 https://reactome.org/PathwayBrowser/#/R-XTR-177784 ribose 5-phosphate <=> D-ribulose 5-phosphate IEA Xenopus tropicalis 78346 R-XTR-2393939 https://reactome.org/PathwayBrowser/#/R-XTR-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 78346 R-XTR-2393954 https://reactome.org/PathwayBrowser/#/R-XTR-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 78346 R-XTR-5696049 https://reactome.org/PathwayBrowser/#/R-XTR-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 78346 R-XTR-6787329 https://reactome.org/PathwayBrowser/#/R-XTR-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Xenopus tropicalis 78346 R-XTR-71306 https://reactome.org/PathwayBrowser/#/R-XTR-71306 D-ribulose 5-phosphate <=> ribose 5-phosphate IEA Xenopus tropicalis 78346 R-XTR-71324 https://reactome.org/PathwayBrowser/#/R-XTR-71324 ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Xenopus tropicalis 78346 R-XTR-73580 https://reactome.org/PathwayBrowser/#/R-XTR-73580 D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate IEA Xenopus tropicalis 78346 R-XTR-8955844 https://reactome.org/PathwayBrowser/#/R-XTR-8955844 RBKS phosphorylates ribose to R5P IEA Xenopus tropicalis 78436 R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 78436 R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 78436 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 78436 R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 78436 R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 78436 R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 78436 R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 78436 R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 78438 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 78438 R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 78438 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 78438 R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 78438 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 78438 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 78438 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 78438 R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 78438 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 78438 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 78438 R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 78438 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 78438 R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 78438 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 78438 R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 78438 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 78438 R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 78445 R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 78445 R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 78445 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 78445 R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 78445 R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 78445 R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 78445 R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 78445 R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 78447 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 78447 R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 78447 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 78447 R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 78447 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 78447 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 78447 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 78447 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 78447 R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 78447 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 78447 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 78447 R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 78447 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 78447 R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 78447 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 78447 R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 78447 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 78447 R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 78452 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 78452 R-BTA-9845538 https://reactome.org/PathwayBrowser/#/R-BTA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Bos taurus 78452 R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 78452 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 78452 R-CFA-9845538 https://reactome.org/PathwayBrowser/#/R-CFA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Canis familiaris 78452 R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 78452 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 78452 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 78452 R-GGA-9845538 https://reactome.org/PathwayBrowser/#/R-GGA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Gallus gallus 78452 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 78452 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 78452 R-HSA-9845538 https://reactome.org/PathwayBrowser/#/R-HSA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides TAS Homo sapiens 78452 R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 78452 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 78452 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 78452 R-MMU-9845538 https://reactome.org/PathwayBrowser/#/R-MMU-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Mus musculus 78452 R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 78452 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 78452 R-RNO-9845538 https://reactome.org/PathwayBrowser/#/R-RNO-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Rattus norvegicus 78452 R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 78452 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 78452 R-SSC-9845538 https://reactome.org/PathwayBrowser/#/R-SSC-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Sus scrofa 78452 R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 78452 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 78452 R-XTR-9845538 https://reactome.org/PathwayBrowser/#/R-XTR-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Xenopus tropicalis 78452 R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 78455 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 78455 R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 78455 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 78455 R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 78455 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 78455 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 78455 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 78455 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 78455 R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 78455 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 78455 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 78455 R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 78455 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 78455 R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 78455 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 78455 R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 78455 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 78455 R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 78484 R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 78484 R-BTA-9845516 https://reactome.org/PathwayBrowser/#/R-BTA-9845516 B3GALT4 transfers Gal to gangliosides IEA Bos taurus 78484 R-BTA-9845538 https://reactome.org/PathwayBrowser/#/R-BTA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Bos taurus 78484 R-CEL-9845516 https://reactome.org/PathwayBrowser/#/R-CEL-9845516 B3GALT4 transfers Gal to gangliosides IEA Caenorhabditis elegans 78484 R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 78484 R-CFA-9845516 https://reactome.org/PathwayBrowser/#/R-CFA-9845516 B3GALT4 transfers Gal to gangliosides IEA Canis familiaris 78484 R-CFA-9845538 https://reactome.org/PathwayBrowser/#/R-CFA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Canis familiaris 78484 R-DME-9845516 https://reactome.org/PathwayBrowser/#/R-DME-9845516 B3GALT4 transfers Gal to gangliosides IEA Drosophila melanogaster 78484 R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 78484 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 78484 R-GGA-9845538 https://reactome.org/PathwayBrowser/#/R-GGA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Gallus gallus 78484 R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 78484 R-HSA-9845516 https://reactome.org/PathwayBrowser/#/R-HSA-9845516 B3GALT4 transfers Gal to gangliosides TAS Homo sapiens 78484 R-HSA-9845538 https://reactome.org/PathwayBrowser/#/R-HSA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides TAS Homo sapiens 78484 R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 78484 R-MMU-9845516 https://reactome.org/PathwayBrowser/#/R-MMU-9845516 B3GALT4 transfers Gal to gangliosides IEA Mus musculus 78484 R-MMU-9845538 https://reactome.org/PathwayBrowser/#/R-MMU-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Mus musculus 78484 R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 78484 R-RNO-9845516 https://reactome.org/PathwayBrowser/#/R-RNO-9845516 B3GALT4 transfers Gal to gangliosides IEA Rattus norvegicus 78484 R-RNO-9845538 https://reactome.org/PathwayBrowser/#/R-RNO-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Rattus norvegicus 78484 R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 78484 R-SSC-9845516 https://reactome.org/PathwayBrowser/#/R-SSC-9845516 B3GALT4 transfers Gal to gangliosides IEA Sus scrofa 78484 R-SSC-9845538 https://reactome.org/PathwayBrowser/#/R-SSC-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Sus scrofa 78484 R-XTR-9845516 https://reactome.org/PathwayBrowser/#/R-XTR-9845516 B3GALT4 transfers Gal to gangliosides IEA Xenopus tropicalis 78484 R-XTR-9845538 https://reactome.org/PathwayBrowser/#/R-XTR-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Xenopus tropicalis 78485 R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 78485 R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 78485 R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 78485 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 78485 R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 78485 R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 78485 R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 78485 R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 78486 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 78486 R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 78486 R-BTA-9845516 https://reactome.org/PathwayBrowser/#/R-BTA-9845516 B3GALT4 transfers Gal to gangliosides IEA Bos taurus 78486 R-CEL-9845516 https://reactome.org/PathwayBrowser/#/R-CEL-9845516 B3GALT4 transfers Gal to gangliosides IEA Caenorhabditis elegans 78486 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 78486 R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 78486 R-CFA-9845516 https://reactome.org/PathwayBrowser/#/R-CFA-9845516 B3GALT4 transfers Gal to gangliosides IEA Canis familiaris 78486 R-DME-9845516 https://reactome.org/PathwayBrowser/#/R-DME-9845516 B3GALT4 transfers Gal to gangliosides IEA Drosophila melanogaster 78486 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 78486 R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 78486 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 78486 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 78486 R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 78486 R-HSA-9845516 https://reactome.org/PathwayBrowser/#/R-HSA-9845516 B3GALT4 transfers Gal to gangliosides TAS Homo sapiens 78486 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 78486 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 78486 R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 78486 R-MMU-9845516 https://reactome.org/PathwayBrowser/#/R-MMU-9845516 B3GALT4 transfers Gal to gangliosides IEA Mus musculus 78486 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 78486 R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 78486 R-RNO-9845516 https://reactome.org/PathwayBrowser/#/R-RNO-9845516 B3GALT4 transfers Gal to gangliosides IEA Rattus norvegicus 78486 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 78486 R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 78486 R-SSC-9845516 https://reactome.org/PathwayBrowser/#/R-SSC-9845516 B3GALT4 transfers Gal to gangliosides IEA Sus scrofa 78486 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 78486 R-XTR-9845516 https://reactome.org/PathwayBrowser/#/R-XTR-9845516 B3GALT4 transfers Gal to gangliosides IEA Xenopus tropicalis 78539 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 78539 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 78539 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 78539 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 78539 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 78539 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 78539 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 78539 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 78539 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 78539 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 78539 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 78539 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 78542 R-BTA-9845516 https://reactome.org/PathwayBrowser/#/R-BTA-9845516 B3GALT4 transfers Gal to gangliosides IEA Bos taurus 78542 R-CEL-9845516 https://reactome.org/PathwayBrowser/#/R-CEL-9845516 B3GALT4 transfers Gal to gangliosides IEA Caenorhabditis elegans 78542 R-CFA-9845516 https://reactome.org/PathwayBrowser/#/R-CFA-9845516 B3GALT4 transfers Gal to gangliosides IEA Canis familiaris 78542 R-DME-9845516 https://reactome.org/PathwayBrowser/#/R-DME-9845516 B3GALT4 transfers Gal to gangliosides IEA Drosophila melanogaster 78542 R-HSA-9845516 https://reactome.org/PathwayBrowser/#/R-HSA-9845516 B3GALT4 transfers Gal to gangliosides TAS Homo sapiens 78542 R-MMU-9845516 https://reactome.org/PathwayBrowser/#/R-MMU-9845516 B3GALT4 transfers Gal to gangliosides IEA Mus musculus 78542 R-RNO-9845516 https://reactome.org/PathwayBrowser/#/R-RNO-9845516 B3GALT4 transfers Gal to gangliosides IEA Rattus norvegicus 78542 R-SSC-9845516 https://reactome.org/PathwayBrowser/#/R-SSC-9845516 B3GALT4 transfers Gal to gangliosides IEA Sus scrofa 78542 R-XTR-9845516 https://reactome.org/PathwayBrowser/#/R-XTR-9845516 B3GALT4 transfers Gal to gangliosides IEA Xenopus tropicalis 78544 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 78544 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 78544 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 78568 R-BTA-9845538 https://reactome.org/PathwayBrowser/#/R-BTA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Bos taurus 78568 R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 78568 R-BTA-9846305 https://reactome.org/PathwayBrowser/#/R-BTA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Bos taurus 78568 R-CFA-9845538 https://reactome.org/PathwayBrowser/#/R-CFA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Canis familiaris 78568 R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 78568 R-CFA-9846305 https://reactome.org/PathwayBrowser/#/R-CFA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Canis familiaris 78568 R-GGA-9845538 https://reactome.org/PathwayBrowser/#/R-GGA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Gallus gallus 78568 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 78568 R-GGA-9846305 https://reactome.org/PathwayBrowser/#/R-GGA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Gallus gallus 78568 R-HSA-9845538 https://reactome.org/PathwayBrowser/#/R-HSA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides TAS Homo sapiens 78568 R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 78568 R-HSA-9846305 https://reactome.org/PathwayBrowser/#/R-HSA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b TAS Homo sapiens 78568 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 78568 R-MMU-9845538 https://reactome.org/PathwayBrowser/#/R-MMU-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Mus musculus 78568 R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 78568 R-MMU-9846305 https://reactome.org/PathwayBrowser/#/R-MMU-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Mus musculus 78568 R-RNO-9845538 https://reactome.org/PathwayBrowser/#/R-RNO-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Rattus norvegicus 78568 R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 78568 R-RNO-9846305 https://reactome.org/PathwayBrowser/#/R-RNO-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Rattus norvegicus 78568 R-SSC-9845538 https://reactome.org/PathwayBrowser/#/R-SSC-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Sus scrofa 78568 R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 78568 R-SSC-9846305 https://reactome.org/PathwayBrowser/#/R-SSC-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Sus scrofa 78568 R-XTR-9845538 https://reactome.org/PathwayBrowser/#/R-XTR-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Xenopus tropicalis 78568 R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 78568 R-XTR-9846305 https://reactome.org/PathwayBrowser/#/R-XTR-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Xenopus tropicalis 78569 R-BTA-9846305 https://reactome.org/PathwayBrowser/#/R-BTA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Bos taurus 78569 R-CFA-9846305 https://reactome.org/PathwayBrowser/#/R-CFA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Canis familiaris 78569 R-GGA-9846305 https://reactome.org/PathwayBrowser/#/R-GGA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Gallus gallus 78569 R-HSA-9846305 https://reactome.org/PathwayBrowser/#/R-HSA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b TAS Homo sapiens 78569 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 78569 R-MMU-9846305 https://reactome.org/PathwayBrowser/#/R-MMU-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Mus musculus 78569 R-RNO-9846305 https://reactome.org/PathwayBrowser/#/R-RNO-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Rattus norvegicus 78569 R-SSC-9846305 https://reactome.org/PathwayBrowser/#/R-SSC-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Sus scrofa 78569 R-XTR-9846305 https://reactome.org/PathwayBrowser/#/R-XTR-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Xenopus tropicalis 78576 R-BTA-5423647 https://reactome.org/PathwayBrowser/#/R-BTA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Bos taurus 78576 R-BTA-5423678 https://reactome.org/PathwayBrowser/#/R-BTA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Bos taurus 78576 R-CEL-5423647 https://reactome.org/PathwayBrowser/#/R-CEL-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Caenorhabditis elegans 78576 R-CFA-5423647 https://reactome.org/PathwayBrowser/#/R-CFA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Canis familiaris 78576 R-DDI-5423647 https://reactome.org/PathwayBrowser/#/R-DDI-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Dictyostelium discoideum 78576 R-DME-5423647 https://reactome.org/PathwayBrowser/#/R-DME-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Drosophila melanogaster 78576 R-DRE-5423647 https://reactome.org/PathwayBrowser/#/R-DRE-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Danio rerio 78576 R-DRE-5423678 https://reactome.org/PathwayBrowser/#/R-DRE-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Danio rerio 78576 R-GGA-5423678 https://reactome.org/PathwayBrowser/#/R-GGA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Gallus gallus 78576 R-HSA-5423647 https://reactome.org/PathwayBrowser/#/R-HSA-5423647 CYP2A13 oxidises AFM1 to AFM1E TAS Homo sapiens 78576 R-HSA-5423678 https://reactome.org/PathwayBrowser/#/R-HSA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 TAS Homo sapiens 78576 R-MMU-5423647 https://reactome.org/PathwayBrowser/#/R-MMU-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Mus musculus 78576 R-MMU-5423678 https://reactome.org/PathwayBrowser/#/R-MMU-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Mus musculus 78576 R-RNO-5423647 https://reactome.org/PathwayBrowser/#/R-RNO-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Rattus norvegicus 78576 R-RNO-5423678 https://reactome.org/PathwayBrowser/#/R-RNO-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Rattus norvegicus 78576 R-SSC-5423647 https://reactome.org/PathwayBrowser/#/R-SSC-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Sus scrofa 78576 R-SSC-5423678 https://reactome.org/PathwayBrowser/#/R-SSC-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Sus scrofa 78576 R-XTR-5423647 https://reactome.org/PathwayBrowser/#/R-XTR-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Xenopus tropicalis 78577 R-BTA-5423647 https://reactome.org/PathwayBrowser/#/R-BTA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Bos taurus 78577 R-CEL-5423647 https://reactome.org/PathwayBrowser/#/R-CEL-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Caenorhabditis elegans 78577 R-CFA-5423647 https://reactome.org/PathwayBrowser/#/R-CFA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Canis familiaris 78577 R-DDI-5423647 https://reactome.org/PathwayBrowser/#/R-DDI-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Dictyostelium discoideum 78577 R-DME-5423647 https://reactome.org/PathwayBrowser/#/R-DME-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Drosophila melanogaster 78577 R-DRE-5423647 https://reactome.org/PathwayBrowser/#/R-DRE-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Danio rerio 78577 R-HSA-5423647 https://reactome.org/PathwayBrowser/#/R-HSA-5423647 CYP2A13 oxidises AFM1 to AFM1E TAS Homo sapiens 78577 R-MMU-5423647 https://reactome.org/PathwayBrowser/#/R-MMU-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Mus musculus 78577 R-RNO-5423647 https://reactome.org/PathwayBrowser/#/R-RNO-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Rattus norvegicus 78577 R-SSC-5423647 https://reactome.org/PathwayBrowser/#/R-SSC-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Sus scrofa 78577 R-XTR-5423647 https://reactome.org/PathwayBrowser/#/R-XTR-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Xenopus tropicalis 78578 R-BTA-5433067 https://reactome.org/PathwayBrowser/#/R-BTA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Bos taurus 78578 R-BTA-5433074 https://reactome.org/PathwayBrowser/#/R-BTA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Bos taurus 78578 R-CEL-5433074 https://reactome.org/PathwayBrowser/#/R-CEL-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Caenorhabditis elegans 78578 R-CFA-5433067 https://reactome.org/PathwayBrowser/#/R-CFA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Canis familiaris 78578 R-CFA-5433074 https://reactome.org/PathwayBrowser/#/R-CFA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Canis familiaris 78578 R-DDI-5433074 https://reactome.org/PathwayBrowser/#/R-DDI-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Dictyostelium discoideum 78578 R-DME-5433067 https://reactome.org/PathwayBrowser/#/R-DME-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Drosophila melanogaster 78578 R-DME-5433074 https://reactome.org/PathwayBrowser/#/R-DME-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Drosophila melanogaster 78578 R-DRE-9638046 https://reactome.org/PathwayBrowser/#/R-DRE-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Danio rerio 78578 R-GGA-5433067 https://reactome.org/PathwayBrowser/#/R-GGA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Gallus gallus 78578 R-GGA-5433074 https://reactome.org/PathwayBrowser/#/R-GGA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Gallus gallus 78578 R-HSA-5433066 https://reactome.org/PathwayBrowser/#/R-HSA-5433066 Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C TAS Homo sapiens 78578 R-HSA-5433067 https://reactome.org/PathwayBrowser/#/R-HSA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG TAS Homo sapiens 78578 R-HSA-5433074 https://reactome.org/PathwayBrowser/#/R-HSA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 78578 R-HSA-5490269 https://reactome.org/PathwayBrowser/#/R-HSA-5490269 AFXBO-C, AFNBO-C translocate from extracellular region to cytosol TAS Homo sapiens 78578 R-HSA-9638046 https://reactome.org/PathwayBrowser/#/R-HSA-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 78578 R-MMU-5433067 https://reactome.org/PathwayBrowser/#/R-MMU-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Mus musculus 78578 R-MMU-5433074 https://reactome.org/PathwayBrowser/#/R-MMU-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 78578 R-MMU-9638046 https://reactome.org/PathwayBrowser/#/R-MMU-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 78578 R-RNO-5433067 https://reactome.org/PathwayBrowser/#/R-RNO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Rattus norvegicus 78578 R-RNO-5433074 https://reactome.org/PathwayBrowser/#/R-RNO-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 78578 R-RNO-9638046 https://reactome.org/PathwayBrowser/#/R-RNO-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 78578 R-SPO-5433067 https://reactome.org/PathwayBrowser/#/R-SPO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Schizosaccharomyces pombe 78578 R-SSC-5433067 https://reactome.org/PathwayBrowser/#/R-SSC-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Sus scrofa 78578 R-SSC-5433074 https://reactome.org/PathwayBrowser/#/R-SSC-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Sus scrofa 78578 R-XTR-5433074 https://reactome.org/PathwayBrowser/#/R-XTR-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 78578 R-XTR-9638046 https://reactome.org/PathwayBrowser/#/R-XTR-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 78579 R-BTA-5433067 https://reactome.org/PathwayBrowser/#/R-BTA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Bos taurus 78579 R-BTA-5433072 https://reactome.org/PathwayBrowser/#/R-BTA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Bos taurus 78579 R-CEL-5433072 https://reactome.org/PathwayBrowser/#/R-CEL-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Caenorhabditis elegans 78579 R-CFA-5433067 https://reactome.org/PathwayBrowser/#/R-CFA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Canis familiaris 78579 R-CFA-5433072 https://reactome.org/PathwayBrowser/#/R-CFA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Canis familiaris 78579 R-DME-5433067 https://reactome.org/PathwayBrowser/#/R-DME-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Drosophila melanogaster 78579 R-DME-5433072 https://reactome.org/PathwayBrowser/#/R-DME-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Drosophila melanogaster 78579 R-GGA-5433067 https://reactome.org/PathwayBrowser/#/R-GGA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Gallus gallus 78579 R-GGA-5433072 https://reactome.org/PathwayBrowser/#/R-GGA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Gallus gallus 78579 R-HSA-5433067 https://reactome.org/PathwayBrowser/#/R-HSA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG TAS Homo sapiens 78579 R-HSA-5433072 https://reactome.org/PathwayBrowser/#/R-HSA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG TAS Homo sapiens 78579 R-MMU-5433067 https://reactome.org/PathwayBrowser/#/R-MMU-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Mus musculus 78579 R-MMU-5433072 https://reactome.org/PathwayBrowser/#/R-MMU-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Mus musculus 78579 R-RNO-5433067 https://reactome.org/PathwayBrowser/#/R-RNO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Rattus norvegicus 78579 R-RNO-5433072 https://reactome.org/PathwayBrowser/#/R-RNO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Rattus norvegicus 78579 R-SCE-5433072 https://reactome.org/PathwayBrowser/#/R-SCE-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Saccharomyces cerevisiae 78579 R-SPO-5433067 https://reactome.org/PathwayBrowser/#/R-SPO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Schizosaccharomyces pombe 78579 R-SPO-5433072 https://reactome.org/PathwayBrowser/#/R-SPO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Schizosaccharomyces pombe 78579 R-SSC-5433067 https://reactome.org/PathwayBrowser/#/R-SSC-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Sus scrofa 78579 R-SSC-5433072 https://reactome.org/PathwayBrowser/#/R-SSC-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Sus scrofa 78580 R-BTA-5433074 https://reactome.org/PathwayBrowser/#/R-BTA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Bos taurus 78580 R-CEL-5433074 https://reactome.org/PathwayBrowser/#/R-CEL-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Caenorhabditis elegans 78580 R-CFA-5433074 https://reactome.org/PathwayBrowser/#/R-CFA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Canis familiaris 78580 R-DDI-5433074 https://reactome.org/PathwayBrowser/#/R-DDI-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Dictyostelium discoideum 78580 R-DME-5433074 https://reactome.org/PathwayBrowser/#/R-DME-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Drosophila melanogaster 78580 R-DRE-9638046 https://reactome.org/PathwayBrowser/#/R-DRE-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Danio rerio 78580 R-GGA-5433074 https://reactome.org/PathwayBrowser/#/R-GGA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Gallus gallus 78580 R-HSA-5433066 https://reactome.org/PathwayBrowser/#/R-HSA-5433066 Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C TAS Homo sapiens 78580 R-HSA-5433074 https://reactome.org/PathwayBrowser/#/R-HSA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 78580 R-HSA-5579081 https://reactome.org/PathwayBrowser/#/R-HSA-5579081 Defective ACY1 does not hydrolyse mercapturic acids TAS Homo sapiens 78580 R-HSA-9638046 https://reactome.org/PathwayBrowser/#/R-HSA-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 78580 R-MMU-5433074 https://reactome.org/PathwayBrowser/#/R-MMU-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 78580 R-MMU-9638046 https://reactome.org/PathwayBrowser/#/R-MMU-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 78580 R-RNO-5433074 https://reactome.org/PathwayBrowser/#/R-RNO-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 78580 R-RNO-9638046 https://reactome.org/PathwayBrowser/#/R-RNO-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 78580 R-SSC-5433074 https://reactome.org/PathwayBrowser/#/R-SSC-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Sus scrofa 78580 R-XTR-5433074 https://reactome.org/PathwayBrowser/#/R-XTR-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 78580 R-XTR-9638046 https://reactome.org/PathwayBrowser/#/R-XTR-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 78581 R-BTA-5423653 https://reactome.org/PathwayBrowser/#/R-BTA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Bos taurus 78581 R-BTA-5433072 https://reactome.org/PathwayBrowser/#/R-BTA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Bos taurus 78581 R-CEL-5433072 https://reactome.org/PathwayBrowser/#/R-CEL-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Caenorhabditis elegans 78581 R-CFA-5423653 https://reactome.org/PathwayBrowser/#/R-CFA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Canis familiaris 78581 R-CFA-5433072 https://reactome.org/PathwayBrowser/#/R-CFA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Canis familiaris 78581 R-DDI-5423653 https://reactome.org/PathwayBrowser/#/R-DDI-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Dictyostelium discoideum 78581 R-DME-5423653 https://reactome.org/PathwayBrowser/#/R-DME-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Drosophila melanogaster 78581 R-DME-5433072 https://reactome.org/PathwayBrowser/#/R-DME-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Drosophila melanogaster 78581 R-DRE-5423653 https://reactome.org/PathwayBrowser/#/R-DRE-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Danio rerio 78581 R-GGA-5423653 https://reactome.org/PathwayBrowser/#/R-GGA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Gallus gallus 78581 R-GGA-5433072 https://reactome.org/PathwayBrowser/#/R-GGA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Gallus gallus 78581 R-HSA-5423653 https://reactome.org/PathwayBrowser/#/R-HSA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO TAS Homo sapiens 78581 R-HSA-5433072 https://reactome.org/PathwayBrowser/#/R-HSA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG TAS Homo sapiens 78581 R-HSA-5490230 https://reactome.org/PathwayBrowser/#/R-HSA-5490230 AFXBO-SG, AFNBO-SG translocate from cytosol to extracellular region TAS Homo sapiens 78581 R-HSA-5602984 https://reactome.org/PathwayBrowser/#/R-HSA-5602984 Defective GGT1 does not hydrolyse glutamate from AFXBO-SG, AFNBO-SG TAS Homo sapiens 78581 R-MMU-5423653 https://reactome.org/PathwayBrowser/#/R-MMU-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Mus musculus 78581 R-MMU-5433072 https://reactome.org/PathwayBrowser/#/R-MMU-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Mus musculus 78581 R-RNO-5423653 https://reactome.org/PathwayBrowser/#/R-RNO-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Rattus norvegicus 78581 R-RNO-5433072 https://reactome.org/PathwayBrowser/#/R-RNO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Rattus norvegicus 78581 R-SCE-5433072 https://reactome.org/PathwayBrowser/#/R-SCE-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Saccharomyces cerevisiae 78581 R-SPO-5433072 https://reactome.org/PathwayBrowser/#/R-SPO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Schizosaccharomyces pombe 78581 R-SSC-5423653 https://reactome.org/PathwayBrowser/#/R-SSC-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Sus scrofa 78581 R-SSC-5433072 https://reactome.org/PathwayBrowser/#/R-SSC-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Sus scrofa 78581 R-XTR-5423653 https://reactome.org/PathwayBrowser/#/R-XTR-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Xenopus tropicalis 78582 R-BTA-5423664 https://reactome.org/PathwayBrowser/#/R-BTA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Bos taurus 78582 R-CFA-5423664 https://reactome.org/PathwayBrowser/#/R-CFA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Canis familiaris 78582 R-DRE-5423664 https://reactome.org/PathwayBrowser/#/R-DRE-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Danio rerio 78582 R-GGA-5423664 https://reactome.org/PathwayBrowser/#/R-GGA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Gallus gallus 78582 R-HSA-5423664 https://reactome.org/PathwayBrowser/#/R-HSA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 TAS Homo sapiens 78582 R-MMU-5423664 https://reactome.org/PathwayBrowser/#/R-MMU-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Mus musculus 78582 R-RNO-5423664 https://reactome.org/PathwayBrowser/#/R-RNO-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Rattus norvegicus 78582 R-SSC-5423664 https://reactome.org/PathwayBrowser/#/R-SSC-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Sus scrofa 78582 R-XTR-5423664 https://reactome.org/PathwayBrowser/#/R-XTR-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Xenopus tropicalis 78583 R-BTA-5433067 https://reactome.org/PathwayBrowser/#/R-BTA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Bos taurus 78583 R-BTA-5433074 https://reactome.org/PathwayBrowser/#/R-BTA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Bos taurus 78583 R-CEL-5433074 https://reactome.org/PathwayBrowser/#/R-CEL-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Caenorhabditis elegans 78583 R-CFA-5433067 https://reactome.org/PathwayBrowser/#/R-CFA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Canis familiaris 78583 R-CFA-5433074 https://reactome.org/PathwayBrowser/#/R-CFA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Canis familiaris 78583 R-DDI-5433074 https://reactome.org/PathwayBrowser/#/R-DDI-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Dictyostelium discoideum 78583 R-DME-5433067 https://reactome.org/PathwayBrowser/#/R-DME-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Drosophila melanogaster 78583 R-DME-5433074 https://reactome.org/PathwayBrowser/#/R-DME-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Drosophila melanogaster 78583 R-DRE-9638046 https://reactome.org/PathwayBrowser/#/R-DRE-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Danio rerio 78583 R-GGA-5433067 https://reactome.org/PathwayBrowser/#/R-GGA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Gallus gallus 78583 R-GGA-5433074 https://reactome.org/PathwayBrowser/#/R-GGA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Gallus gallus 78583 R-HSA-5433066 https://reactome.org/PathwayBrowser/#/R-HSA-5433066 Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C TAS Homo sapiens 78583 R-HSA-5433067 https://reactome.org/PathwayBrowser/#/R-HSA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG TAS Homo sapiens 78583 R-HSA-5433074 https://reactome.org/PathwayBrowser/#/R-HSA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 78583 R-HSA-5490269 https://reactome.org/PathwayBrowser/#/R-HSA-5490269 AFXBO-C, AFNBO-C translocate from extracellular region to cytosol TAS Homo sapiens 78583 R-HSA-9638046 https://reactome.org/PathwayBrowser/#/R-HSA-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 78583 R-MMU-5433067 https://reactome.org/PathwayBrowser/#/R-MMU-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Mus musculus 78583 R-MMU-5433074 https://reactome.org/PathwayBrowser/#/R-MMU-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 78583 R-MMU-9638046 https://reactome.org/PathwayBrowser/#/R-MMU-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 78583 R-RNO-5433067 https://reactome.org/PathwayBrowser/#/R-RNO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Rattus norvegicus 78583 R-RNO-5433074 https://reactome.org/PathwayBrowser/#/R-RNO-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 78583 R-RNO-9638046 https://reactome.org/PathwayBrowser/#/R-RNO-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 78583 R-SPO-5433067 https://reactome.org/PathwayBrowser/#/R-SPO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Schizosaccharomyces pombe 78583 R-SSC-5433067 https://reactome.org/PathwayBrowser/#/R-SSC-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Sus scrofa 78583 R-SSC-5433074 https://reactome.org/PathwayBrowser/#/R-SSC-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Sus scrofa 78583 R-XTR-5433074 https://reactome.org/PathwayBrowser/#/R-XTR-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 78583 R-XTR-9638046 https://reactome.org/PathwayBrowser/#/R-XTR-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 78584 R-BTA-5433067 https://reactome.org/PathwayBrowser/#/R-BTA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Bos taurus 78584 R-BTA-5433072 https://reactome.org/PathwayBrowser/#/R-BTA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Bos taurus 78584 R-CEL-5433072 https://reactome.org/PathwayBrowser/#/R-CEL-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Caenorhabditis elegans 78584 R-CFA-5433067 https://reactome.org/PathwayBrowser/#/R-CFA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Canis familiaris 78584 R-CFA-5433072 https://reactome.org/PathwayBrowser/#/R-CFA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Canis familiaris 78584 R-DME-5433067 https://reactome.org/PathwayBrowser/#/R-DME-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Drosophila melanogaster 78584 R-DME-5433072 https://reactome.org/PathwayBrowser/#/R-DME-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Drosophila melanogaster 78584 R-GGA-5433067 https://reactome.org/PathwayBrowser/#/R-GGA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Gallus gallus 78584 R-GGA-5433072 https://reactome.org/PathwayBrowser/#/R-GGA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Gallus gallus 78584 R-HSA-5433067 https://reactome.org/PathwayBrowser/#/R-HSA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG TAS Homo sapiens 78584 R-HSA-5433072 https://reactome.org/PathwayBrowser/#/R-HSA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG TAS Homo sapiens 78584 R-MMU-5433067 https://reactome.org/PathwayBrowser/#/R-MMU-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Mus musculus 78584 R-MMU-5433072 https://reactome.org/PathwayBrowser/#/R-MMU-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Mus musculus 78584 R-RNO-5433067 https://reactome.org/PathwayBrowser/#/R-RNO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Rattus norvegicus 78584 R-RNO-5433072 https://reactome.org/PathwayBrowser/#/R-RNO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Rattus norvegicus 78584 R-SCE-5433072 https://reactome.org/PathwayBrowser/#/R-SCE-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Saccharomyces cerevisiae 78584 R-SPO-5433067 https://reactome.org/PathwayBrowser/#/R-SPO-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Schizosaccharomyces pombe 78584 R-SPO-5433072 https://reactome.org/PathwayBrowser/#/R-SPO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Schizosaccharomyces pombe 78584 R-SSC-5433067 https://reactome.org/PathwayBrowser/#/R-SSC-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Sus scrofa 78584 R-SSC-5433072 https://reactome.org/PathwayBrowser/#/R-SSC-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Sus scrofa 78585 R-BTA-5433074 https://reactome.org/PathwayBrowser/#/R-BTA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Bos taurus 78585 R-CEL-5433074 https://reactome.org/PathwayBrowser/#/R-CEL-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Caenorhabditis elegans 78585 R-CFA-5433074 https://reactome.org/PathwayBrowser/#/R-CFA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Canis familiaris 78585 R-DDI-5433074 https://reactome.org/PathwayBrowser/#/R-DDI-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Dictyostelium discoideum 78585 R-DME-5433074 https://reactome.org/PathwayBrowser/#/R-DME-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Drosophila melanogaster 78585 R-DRE-9638046 https://reactome.org/PathwayBrowser/#/R-DRE-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Danio rerio 78585 R-GGA-5433074 https://reactome.org/PathwayBrowser/#/R-GGA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Gallus gallus 78585 R-HSA-5433066 https://reactome.org/PathwayBrowser/#/R-HSA-5433066 Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C TAS Homo sapiens 78585 R-HSA-5433074 https://reactome.org/PathwayBrowser/#/R-HSA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 78585 R-HSA-5579081 https://reactome.org/PathwayBrowser/#/R-HSA-5579081 Defective ACY1 does not hydrolyse mercapturic acids TAS Homo sapiens 78585 R-HSA-9638046 https://reactome.org/PathwayBrowser/#/R-HSA-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 78585 R-MMU-5433074 https://reactome.org/PathwayBrowser/#/R-MMU-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 78585 R-MMU-9638046 https://reactome.org/PathwayBrowser/#/R-MMU-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 78585 R-RNO-5433074 https://reactome.org/PathwayBrowser/#/R-RNO-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 78585 R-RNO-9638046 https://reactome.org/PathwayBrowser/#/R-RNO-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 78585 R-SSC-5433074 https://reactome.org/PathwayBrowser/#/R-SSC-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Sus scrofa 78585 R-XTR-5433074 https://reactome.org/PathwayBrowser/#/R-XTR-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 78585 R-XTR-9638046 https://reactome.org/PathwayBrowser/#/R-XTR-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 78586 R-BTA-5423653 https://reactome.org/PathwayBrowser/#/R-BTA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Bos taurus 78586 R-BTA-5423672 https://reactome.org/PathwayBrowser/#/R-BTA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Bos taurus 78586 R-CFA-5423653 https://reactome.org/PathwayBrowser/#/R-CFA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Canis familiaris 78586 R-CFA-5423672 https://reactome.org/PathwayBrowser/#/R-CFA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Canis familiaris 78586 R-DDI-5423653 https://reactome.org/PathwayBrowser/#/R-DDI-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Dictyostelium discoideum 78586 R-DME-5423653 https://reactome.org/PathwayBrowser/#/R-DME-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Drosophila melanogaster 78586 R-DRE-5423653 https://reactome.org/PathwayBrowser/#/R-DRE-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Danio rerio 78586 R-DRE-5423672 https://reactome.org/PathwayBrowser/#/R-DRE-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Danio rerio 78586 R-GGA-5423653 https://reactome.org/PathwayBrowser/#/R-GGA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Gallus gallus 78586 R-GGA-5423672 https://reactome.org/PathwayBrowser/#/R-GGA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Gallus gallus 78586 R-HSA-5423653 https://reactome.org/PathwayBrowser/#/R-HSA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO TAS Homo sapiens 78586 R-HSA-5423672 https://reactome.org/PathwayBrowser/#/R-HSA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO TAS Homo sapiens 78586 R-MMU-5423653 https://reactome.org/PathwayBrowser/#/R-MMU-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Mus musculus 78586 R-MMU-5423672 https://reactome.org/PathwayBrowser/#/R-MMU-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Mus musculus 78586 R-RNO-5423653 https://reactome.org/PathwayBrowser/#/R-RNO-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Rattus norvegicus 78586 R-RNO-5423672 https://reactome.org/PathwayBrowser/#/R-RNO-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Rattus norvegicus 78586 R-SSC-5423653 https://reactome.org/PathwayBrowser/#/R-SSC-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Sus scrofa 78586 R-SSC-5423672 https://reactome.org/PathwayBrowser/#/R-SSC-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Sus scrofa 78586 R-XTR-5423653 https://reactome.org/PathwayBrowser/#/R-XTR-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Xenopus tropicalis 78586 R-XTR-5423672 https://reactome.org/PathwayBrowser/#/R-XTR-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Xenopus tropicalis 78587 R-BTA-5423653 https://reactome.org/PathwayBrowser/#/R-BTA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Bos taurus 78587 R-BTA-5433072 https://reactome.org/PathwayBrowser/#/R-BTA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Bos taurus 78587 R-CEL-5433072 https://reactome.org/PathwayBrowser/#/R-CEL-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Caenorhabditis elegans 78587 R-CFA-5423653 https://reactome.org/PathwayBrowser/#/R-CFA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Canis familiaris 78587 R-CFA-5433072 https://reactome.org/PathwayBrowser/#/R-CFA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Canis familiaris 78587 R-DDI-5423653 https://reactome.org/PathwayBrowser/#/R-DDI-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Dictyostelium discoideum 78587 R-DME-5423653 https://reactome.org/PathwayBrowser/#/R-DME-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Drosophila melanogaster 78587 R-DME-5433072 https://reactome.org/PathwayBrowser/#/R-DME-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Drosophila melanogaster 78587 R-DRE-5423653 https://reactome.org/PathwayBrowser/#/R-DRE-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Danio rerio 78587 R-GGA-5423653 https://reactome.org/PathwayBrowser/#/R-GGA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Gallus gallus 78587 R-GGA-5433072 https://reactome.org/PathwayBrowser/#/R-GGA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Gallus gallus 78587 R-HSA-5423653 https://reactome.org/PathwayBrowser/#/R-HSA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO TAS Homo sapiens 78587 R-HSA-5433072 https://reactome.org/PathwayBrowser/#/R-HSA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG TAS Homo sapiens 78587 R-HSA-5490230 https://reactome.org/PathwayBrowser/#/R-HSA-5490230 AFXBO-SG, AFNBO-SG translocate from cytosol to extracellular region TAS Homo sapiens 78587 R-HSA-5602984 https://reactome.org/PathwayBrowser/#/R-HSA-5602984 Defective GGT1 does not hydrolyse glutamate from AFXBO-SG, AFNBO-SG TAS Homo sapiens 78587 R-MMU-5423653 https://reactome.org/PathwayBrowser/#/R-MMU-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Mus musculus 78587 R-MMU-5433072 https://reactome.org/PathwayBrowser/#/R-MMU-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Mus musculus 78587 R-RNO-5423653 https://reactome.org/PathwayBrowser/#/R-RNO-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Rattus norvegicus 78587 R-RNO-5433072 https://reactome.org/PathwayBrowser/#/R-RNO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Rattus norvegicus 78587 R-SCE-5433072 https://reactome.org/PathwayBrowser/#/R-SCE-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Saccharomyces cerevisiae 78587 R-SPO-5433072 https://reactome.org/PathwayBrowser/#/R-SPO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Schizosaccharomyces pombe 78587 R-SSC-5423653 https://reactome.org/PathwayBrowser/#/R-SSC-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Sus scrofa 78587 R-SSC-5433072 https://reactome.org/PathwayBrowser/#/R-SSC-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Sus scrofa 78587 R-XTR-5423653 https://reactome.org/PathwayBrowser/#/R-XTR-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Xenopus tropicalis 78619 R-BTA-1562626 https://reactome.org/PathwayBrowser/#/R-BTA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Bos taurus 78619 R-BTA-5691107 https://reactome.org/PathwayBrowser/#/R-BTA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Bos taurus 78619 R-CEL-1562626 https://reactome.org/PathwayBrowser/#/R-CEL-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Caenorhabditis elegans 78619 R-CEL-5691107 https://reactome.org/PathwayBrowser/#/R-CEL-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Caenorhabditis elegans 78619 R-CFA-1562626 https://reactome.org/PathwayBrowser/#/R-CFA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Canis familiaris 78619 R-CFA-5691107 https://reactome.org/PathwayBrowser/#/R-CFA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Canis familiaris 78619 R-DME-1562626 https://reactome.org/PathwayBrowser/#/R-DME-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Drosophila melanogaster 78619 R-DME-5691107 https://reactome.org/PathwayBrowser/#/R-DME-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Drosophila melanogaster 78619 R-DRE-1562626 https://reactome.org/PathwayBrowser/#/R-DRE-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Danio rerio 78619 R-DRE-5691107 https://reactome.org/PathwayBrowser/#/R-DRE-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Danio rerio 78619 R-GGA-1562626 https://reactome.org/PathwayBrowser/#/R-GGA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Gallus gallus 78619 R-GGA-5691107 https://reactome.org/PathwayBrowser/#/R-GGA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Gallus gallus 78619 R-HSA-1562626 https://reactome.org/PathwayBrowser/#/R-HSA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) TAS Homo sapiens 78619 R-HSA-5691107 https://reactome.org/PathwayBrowser/#/R-HSA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) TAS Homo sapiens 78619 R-MMU-1562626 https://reactome.org/PathwayBrowser/#/R-MMU-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Mus musculus 78619 R-MMU-5691107 https://reactome.org/PathwayBrowser/#/R-MMU-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Mus musculus 78619 R-RNO-1562626 https://reactome.org/PathwayBrowser/#/R-RNO-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Rattus norvegicus 78619 R-RNO-5691107 https://reactome.org/PathwayBrowser/#/R-RNO-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Rattus norvegicus 78619 R-SSC-1562626 https://reactome.org/PathwayBrowser/#/R-SSC-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Sus scrofa 78619 R-SSC-5691107 https://reactome.org/PathwayBrowser/#/R-SSC-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Sus scrofa 78619 R-XTR-1562626 https://reactome.org/PathwayBrowser/#/R-XTR-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Xenopus tropicalis 78619 R-XTR-5691107 https://reactome.org/PathwayBrowser/#/R-XTR-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Xenopus tropicalis 7862 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 7862 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 7862 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 7862 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 7862 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 7862 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 7862 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 7862 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 7862 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 7862 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 7862 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 7862 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 7862 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 7862 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 7862 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 7862 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 7862 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 7862 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 7862 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 7862 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 7862 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 7862 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 78654 R-BTA-8959462 https://reactome.org/PathwayBrowser/#/R-BTA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Bos taurus 78654 R-CEL-8959462 https://reactome.org/PathwayBrowser/#/R-CEL-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Caenorhabditis elegans 78654 R-CFA-8959462 https://reactome.org/PathwayBrowser/#/R-CFA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Canis familiaris 78654 R-DME-8959462 https://reactome.org/PathwayBrowser/#/R-DME-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Drosophila melanogaster 78654 R-DRE-8959462 https://reactome.org/PathwayBrowser/#/R-DRE-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Danio rerio 78654 R-GGA-8959462 https://reactome.org/PathwayBrowser/#/R-GGA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Gallus gallus 78654 R-HSA-8959462 https://reactome.org/PathwayBrowser/#/R-HSA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER TAS Homo sapiens 78654 R-MMU-8959462 https://reactome.org/PathwayBrowser/#/R-MMU-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Mus musculus 78654 R-PFA-8959462 https://reactome.org/PathwayBrowser/#/R-PFA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Plasmodium falciparum 78654 R-RNO-8959462 https://reactome.org/PathwayBrowser/#/R-RNO-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Rattus norvegicus 78654 R-SSC-8959462 https://reactome.org/PathwayBrowser/#/R-SSC-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Sus scrofa 78654 R-XTR-8959462 https://reactome.org/PathwayBrowser/#/R-XTR-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Xenopus tropicalis 78810 R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus 78810 R-BTA-1605632 https://reactome.org/PathwayBrowser/#/R-BTA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Bos taurus 78810 R-BTA-1605724 https://reactome.org/PathwayBrowser/#/R-BTA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Bos taurus 78810 R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus 78810 R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus 78810 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 78810 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 78810 R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 78810 R-BTA-9842115 https://reactome.org/PathwayBrowser/#/R-BTA-9842115 PSAP(195-273) dimer binds PE IEA Bos taurus 78810 R-CEL-1605624 https://reactome.org/PathwayBrowser/#/R-CEL-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Caenorhabditis elegans 78810 R-CEL-1605632 https://reactome.org/PathwayBrowser/#/R-CEL-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Caenorhabditis elegans 78810 R-CEL-1605736 https://reactome.org/PathwayBrowser/#/R-CEL-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Caenorhabditis elegans 78810 R-CEL-1606312 https://reactome.org/PathwayBrowser/#/R-CEL-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Caenorhabditis elegans 78810 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 78810 R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 78810 R-CEL-9842115 https://reactome.org/PathwayBrowser/#/R-CEL-9842115 PSAP(195-273) dimer binds PE IEA Caenorhabditis elegans 78810 R-CFA-1605624 https://reactome.org/PathwayBrowser/#/R-CFA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Canis familiaris 78810 R-CFA-1605632 https://reactome.org/PathwayBrowser/#/R-CFA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Canis familiaris 78810 R-CFA-1605724 https://reactome.org/PathwayBrowser/#/R-CFA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Canis familiaris 78810 R-CFA-1605736 https://reactome.org/PathwayBrowser/#/R-CFA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Canis familiaris 78810 R-CFA-1606312 https://reactome.org/PathwayBrowser/#/R-CFA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Canis familiaris 78810 R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 78810 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 78810 R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 78810 R-CFA-9842115 https://reactome.org/PathwayBrowser/#/R-CFA-9842115 PSAP(195-273) dimer binds PE IEA Canis familiaris 78810 R-DDI-1605624 https://reactome.org/PathwayBrowser/#/R-DDI-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Dictyostelium discoideum 78810 R-DDI-1605632 https://reactome.org/PathwayBrowser/#/R-DDI-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Dictyostelium discoideum 78810 R-DDI-1605736 https://reactome.org/PathwayBrowser/#/R-DDI-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Dictyostelium discoideum 78810 R-DDI-1606312 https://reactome.org/PathwayBrowser/#/R-DDI-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Dictyostelium discoideum 78810 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 78810 R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 78810 R-DDI-9842115 https://reactome.org/PathwayBrowser/#/R-DDI-9842115 PSAP(195-273) dimer binds PE IEA Dictyostelium discoideum 78810 R-DME-1605624 https://reactome.org/PathwayBrowser/#/R-DME-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Drosophila melanogaster 78810 R-DME-1605632 https://reactome.org/PathwayBrowser/#/R-DME-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Drosophila melanogaster 78810 R-DME-1606312 https://reactome.org/PathwayBrowser/#/R-DME-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Drosophila melanogaster 78810 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 78810 R-DME-9842115 https://reactome.org/PathwayBrowser/#/R-DME-9842115 PSAP(195-273) dimer binds PE IEA Drosophila melanogaster 78810 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus 78810 R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus 78810 R-GGA-1605724 https://reactome.org/PathwayBrowser/#/R-GGA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Gallus gallus 78810 R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus 78810 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus 78810 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 78810 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 78810 R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 78810 R-GGA-9842115 https://reactome.org/PathwayBrowser/#/R-GGA-9842115 PSAP(195-273) dimer binds PE IEA Gallus gallus 78810 R-HSA-1605624 https://reactome.org/PathwayBrowser/#/R-HSA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 TAS Homo sapiens 78810 R-HSA-1605632 https://reactome.org/PathwayBrowser/#/R-HSA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE TAS Homo sapiens 78810 R-HSA-1605724 https://reactome.org/PathwayBrowser/#/R-HSA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE TAS Homo sapiens 78810 R-HSA-1605736 https://reactome.org/PathwayBrowser/#/R-HSA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE TAS Homo sapiens 78810 R-HSA-1606312 https://reactome.org/PathwayBrowser/#/R-HSA-1606312 GLB1 hydrolyzes SapB/C:LacCer TAS Homo sapiens 78810 R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 78810 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 78810 R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 78810 R-HSA-9842115 https://reactome.org/PathwayBrowser/#/R-HSA-9842115 PSAP(195-273) dimer binds PE TAS Homo sapiens 78810 R-MMU-1605624 https://reactome.org/PathwayBrowser/#/R-MMU-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Mus musculus 78810 R-MMU-1605632 https://reactome.org/PathwayBrowser/#/R-MMU-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Mus musculus 78810 R-MMU-1605724 https://reactome.org/PathwayBrowser/#/R-MMU-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Mus musculus 78810 R-MMU-1605736 https://reactome.org/PathwayBrowser/#/R-MMU-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Mus musculus 78810 R-MMU-1606312 https://reactome.org/PathwayBrowser/#/R-MMU-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Mus musculus 78810 R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 78810 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 78810 R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 78810 R-MMU-9842115 https://reactome.org/PathwayBrowser/#/R-MMU-9842115 PSAP(195-273) dimer binds PE IEA Mus musculus 78810 R-RNO-1605624 https://reactome.org/PathwayBrowser/#/R-RNO-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Rattus norvegicus 78810 R-RNO-1605632 https://reactome.org/PathwayBrowser/#/R-RNO-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Rattus norvegicus 78810 R-RNO-1605724 https://reactome.org/PathwayBrowser/#/R-RNO-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Rattus norvegicus 78810 R-RNO-1605736 https://reactome.org/PathwayBrowser/#/R-RNO-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Rattus norvegicus 78810 R-RNO-1606312 https://reactome.org/PathwayBrowser/#/R-RNO-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Rattus norvegicus 78810 R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 78810 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 78810 R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 78810 R-RNO-9842115 https://reactome.org/PathwayBrowser/#/R-RNO-9842115 PSAP(195-273) dimer binds PE IEA Rattus norvegicus 78810 R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa 78810 R-SSC-1605632 https://reactome.org/PathwayBrowser/#/R-SSC-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Sus scrofa 78810 R-SSC-1605724 https://reactome.org/PathwayBrowser/#/R-SSC-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Sus scrofa 78810 R-SSC-1605736 https://reactome.org/PathwayBrowser/#/R-SSC-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Sus scrofa 78810 R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa 78810 R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 78810 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 78810 R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 78810 R-SSC-9842115 https://reactome.org/PathwayBrowser/#/R-SSC-9842115 PSAP(195-273) dimer binds PE IEA Sus scrofa 78825 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 78825 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 78825 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus 78825 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 78825 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 78825 R-CEL-9657599 https://reactome.org/PathwayBrowser/#/R-CEL-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Caenorhabditis elegans 78825 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 78825 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 78825 R-CFA-9657599 https://reactome.org/PathwayBrowser/#/R-CFA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Canis familiaris 78825 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 78825 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 78825 R-DME-9657599 https://reactome.org/PathwayBrowser/#/R-DME-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Drosophila melanogaster 78825 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 78825 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 78825 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus 78825 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 78825 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 78825 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 78825 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 78825 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 78825 R-MMU-9657599 https://reactome.org/PathwayBrowser/#/R-MMU-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Mus musculus 78825 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 78825 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 78825 R-RNO-9657599 https://reactome.org/PathwayBrowser/#/R-RNO-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Rattus norvegicus 78825 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 78825 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 78825 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa 78948 R-HSA-6798345 https://reactome.org/PathwayBrowser/#/R-HSA-6798345 PXLP-GCAT dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA TAS Homo sapiens 78948 R-HSA-6798667 https://reactome.org/PathwayBrowser/#/R-HSA-6798667 TDH tetramer oxidises L-Thr to 2A-3OB TAS Homo sapiens 7896 R-BTA-8848355 https://reactome.org/PathwayBrowser/#/R-BTA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Bos taurus 7896 R-BTA-9647994 https://reactome.org/PathwayBrowser/#/R-BTA-9647994 RAS proteins are depalmitoylated IEA Bos taurus 7896 R-CEL-9647994 https://reactome.org/PathwayBrowser/#/R-CEL-9647994 RAS proteins are depalmitoylated IEA Caenorhabditis elegans 7896 R-CFA-8848355 https://reactome.org/PathwayBrowser/#/R-CFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Canis familiaris 7896 R-CFA-9647994 https://reactome.org/PathwayBrowser/#/R-CFA-9647994 RAS proteins are depalmitoylated IEA Canis familiaris 7896 R-DME-9647994 https://reactome.org/PathwayBrowser/#/R-DME-9647994 RAS proteins are depalmitoylated IEA Drosophila melanogaster 7896 R-DRE-9647994 https://reactome.org/PathwayBrowser/#/R-DRE-9647994 RAS proteins are depalmitoylated IEA Danio rerio 7896 R-GGA-8848355 https://reactome.org/PathwayBrowser/#/R-GGA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Gallus gallus 7896 R-GGA-9647994 https://reactome.org/PathwayBrowser/#/R-GGA-9647994 RAS proteins are depalmitoylated IEA Gallus gallus 7896 R-HSA-8848355 https://reactome.org/PathwayBrowser/#/R-HSA-8848355 PNPLA4 hydrolyzes retinyl palmitate TAS Homo sapiens 7896 R-HSA-9027670 https://reactome.org/PathwayBrowser/#/R-HSA-9027670 ESTG binding induces ESR depalmitoylation TAS Homo sapiens 7896 R-HSA-9647994 https://reactome.org/PathwayBrowser/#/R-HSA-9647994 RAS proteins are depalmitoylated TAS Homo sapiens 7896 R-MMU-9647994 https://reactome.org/PathwayBrowser/#/R-MMU-9647994 RAS proteins are depalmitoylated IEA Mus musculus 7896 R-PFA-8848355 https://reactome.org/PathwayBrowser/#/R-PFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Plasmodium falciparum 7896 R-RNO-8848355 https://reactome.org/PathwayBrowser/#/R-RNO-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Rattus norvegicus 7896 R-RNO-9647994 https://reactome.org/PathwayBrowser/#/R-RNO-9647994 RAS proteins are depalmitoylated IEA Rattus norvegicus 7896 R-SSC-8848355 https://reactome.org/PathwayBrowser/#/R-SSC-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Sus scrofa 7896 R-SSC-9647994 https://reactome.org/PathwayBrowser/#/R-SSC-9647994 RAS proteins are depalmitoylated IEA Sus scrofa 7896 R-XTR-8848355 https://reactome.org/PathwayBrowser/#/R-XTR-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Xenopus tropicalis 7903 R-CEL-9717841 https://reactome.org/PathwayBrowser/#/R-CEL-9717841 holo-FDPS dimer binds NBPs IEA Caenorhabditis elegans 7903 R-CFA-9717841 https://reactome.org/PathwayBrowser/#/R-CFA-9717841 holo-FDPS dimer binds NBPs IEA Canis familiaris 7903 R-DDI-9717841 https://reactome.org/PathwayBrowser/#/R-DDI-9717841 holo-FDPS dimer binds NBPs IEA Dictyostelium discoideum 7903 R-DME-9717841 https://reactome.org/PathwayBrowser/#/R-DME-9717841 holo-FDPS dimer binds NBPs IEA Drosophila melanogaster 7903 R-DRE-9717841 https://reactome.org/PathwayBrowser/#/R-DRE-9717841 holo-FDPS dimer binds NBPs IEA Danio rerio 7903 R-GGA-9717841 https://reactome.org/PathwayBrowser/#/R-GGA-9717841 holo-FDPS dimer binds NBPs IEA Gallus gallus 7903 R-HSA-9717841 https://reactome.org/PathwayBrowser/#/R-HSA-9717841 holo-FDPS dimer binds NBPs TAS Homo sapiens 7903 R-MMU-9717841 https://reactome.org/PathwayBrowser/#/R-MMU-9717841 holo-FDPS dimer binds NBPs IEA Mus musculus 7903 R-PFA-9717841 https://reactome.org/PathwayBrowser/#/R-PFA-9717841 holo-FDPS dimer binds NBPs IEA Plasmodium falciparum 7903 R-RNO-9717841 https://reactome.org/PathwayBrowser/#/R-RNO-9717841 holo-FDPS dimer binds NBPs IEA Rattus norvegicus 7903 R-SCE-9717841 https://reactome.org/PathwayBrowser/#/R-SCE-9717841 holo-FDPS dimer binds NBPs IEA Saccharomyces cerevisiae 7903 R-SPO-9717841 https://reactome.org/PathwayBrowser/#/R-SPO-9717841 holo-FDPS dimer binds NBPs IEA Schizosaccharomyces pombe 7903 R-SSC-9717841 https://reactome.org/PathwayBrowser/#/R-SSC-9717841 holo-FDPS dimer binds NBPs IEA Sus scrofa 79218 R-BTA-1605595 https://reactome.org/PathwayBrowser/#/R-BTA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Bos taurus 79218 R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus 79218 R-BTA-1605717 https://reactome.org/PathwayBrowser/#/R-BTA-1605717 GM2A binds and mobilizes ligands IEA Bos taurus 79218 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 79218 R-BTA-9845516 https://reactome.org/PathwayBrowser/#/R-BTA-9845516 B3GALT4 transfers Gal to gangliosides IEA Bos taurus 79218 R-CEL-1605595 https://reactome.org/PathwayBrowser/#/R-CEL-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Caenorhabditis elegans 79218 R-CEL-1605624 https://reactome.org/PathwayBrowser/#/R-CEL-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Caenorhabditis elegans 79218 R-CEL-1605717 https://reactome.org/PathwayBrowser/#/R-CEL-1605717 GM2A binds and mobilizes ligands IEA Caenorhabditis elegans 79218 R-CEL-9845516 https://reactome.org/PathwayBrowser/#/R-CEL-9845516 B3GALT4 transfers Gal to gangliosides IEA Caenorhabditis elegans 79218 R-CFA-1605595 https://reactome.org/PathwayBrowser/#/R-CFA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Canis familiaris 79218 R-CFA-1605624 https://reactome.org/PathwayBrowser/#/R-CFA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Canis familiaris 79218 R-CFA-1605717 https://reactome.org/PathwayBrowser/#/R-CFA-1605717 GM2A binds and mobilizes ligands IEA Canis familiaris 79218 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 79218 R-CFA-9845516 https://reactome.org/PathwayBrowser/#/R-CFA-9845516 B3GALT4 transfers Gal to gangliosides IEA Canis familiaris 79218 R-DDI-1605624 https://reactome.org/PathwayBrowser/#/R-DDI-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Dictyostelium discoideum 79218 R-DME-1605624 https://reactome.org/PathwayBrowser/#/R-DME-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Drosophila melanogaster 79218 R-DME-9845516 https://reactome.org/PathwayBrowser/#/R-DME-9845516 B3GALT4 transfers Gal to gangliosides IEA Drosophila melanogaster 79218 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 79218 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus 79218 R-HSA-1605595 https://reactome.org/PathwayBrowser/#/R-HSA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 TAS Homo sapiens 79218 R-HSA-1605624 https://reactome.org/PathwayBrowser/#/R-HSA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 TAS Homo sapiens 79218 R-HSA-1605717 https://reactome.org/PathwayBrowser/#/R-HSA-1605717 GM2A binds and mobilizes ligands TAS Homo sapiens 79218 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 79218 R-HSA-9845516 https://reactome.org/PathwayBrowser/#/R-HSA-9845516 B3GALT4 transfers Gal to gangliosides TAS Homo sapiens 79218 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 79218 R-MMU-1605595 https://reactome.org/PathwayBrowser/#/R-MMU-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Mus musculus 79218 R-MMU-1605624 https://reactome.org/PathwayBrowser/#/R-MMU-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Mus musculus 79218 R-MMU-1605717 https://reactome.org/PathwayBrowser/#/R-MMU-1605717 GM2A binds and mobilizes ligands IEA Mus musculus 79218 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 79218 R-MMU-9845516 https://reactome.org/PathwayBrowser/#/R-MMU-9845516 B3GALT4 transfers Gal to gangliosides IEA Mus musculus 79218 R-RNO-1605595 https://reactome.org/PathwayBrowser/#/R-RNO-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Rattus norvegicus 79218 R-RNO-1605624 https://reactome.org/PathwayBrowser/#/R-RNO-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Rattus norvegicus 79218 R-RNO-1605717 https://reactome.org/PathwayBrowser/#/R-RNO-1605717 GM2A binds and mobilizes ligands IEA Rattus norvegicus 79218 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 79218 R-RNO-9845516 https://reactome.org/PathwayBrowser/#/R-RNO-9845516 B3GALT4 transfers Gal to gangliosides IEA Rattus norvegicus 79218 R-SSC-1605595 https://reactome.org/PathwayBrowser/#/R-SSC-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Sus scrofa 79218 R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa 79218 R-SSC-1605717 https://reactome.org/PathwayBrowser/#/R-SSC-1605717 GM2A binds and mobilizes ligands IEA Sus scrofa 79218 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 79218 R-SSC-9845516 https://reactome.org/PathwayBrowser/#/R-SSC-9845516 B3GALT4 transfers Gal to gangliosides IEA Sus scrofa 79218 R-XTR-1605624 https://reactome.org/PathwayBrowser/#/R-XTR-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Xenopus tropicalis 79218 R-XTR-1605717 https://reactome.org/PathwayBrowser/#/R-XTR-1605717 GM2A binds and mobilizes ligands IEA Xenopus tropicalis 79218 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 79218 R-XTR-9845516 https://reactome.org/PathwayBrowser/#/R-XTR-9845516 B3GALT4 transfers Gal to gangliosides IEA Xenopus tropicalis 7931 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 7931 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 7931 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 7931 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 7931 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 7931 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 7931 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 7931 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 7931 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 7931 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 7931 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 7939 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 7939 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 7939 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 7939 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 7939 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 7939 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 7939 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 7939 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 7939 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 7939 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 7939 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 7939 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 7939 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 7939 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 7939 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 7939 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 7939 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 7939 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 7939 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 7939 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 7939 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 7939 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 7939 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 7939 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 7939 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 7939 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 7939 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 7939 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 7939 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 7939 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 7939 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 7939 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 7939 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 7939 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 7939 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 7939 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 7939 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 7939 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 7939 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 7939 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 7939 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 7939 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 8005 R-BTA-6789072 https://reactome.org/PathwayBrowser/#/R-BTA-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Bos taurus 8005 R-BTA-6799959 https://reactome.org/PathwayBrowser/#/R-BTA-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Bos taurus 8005 R-BTA-6799977 https://reactome.org/PathwayBrowser/#/R-BTA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Bos taurus 8005 R-BTA-6799981 https://reactome.org/PathwayBrowser/#/R-BTA-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Bos taurus 8005 R-BTA-6801808 https://reactome.org/PathwayBrowser/#/R-BTA-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Bos taurus 8005 R-BTA-6803063 https://reactome.org/PathwayBrowser/#/R-BTA-6803063 RNASEs bind bacterial LPS, PGN IEA Bos taurus 8005 R-CEL-6801808 https://reactome.org/PathwayBrowser/#/R-CEL-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Caenorhabditis elegans 8005 R-CFA-6789072 https://reactome.org/PathwayBrowser/#/R-CFA-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Canis familiaris 8005 R-CFA-6799977 https://reactome.org/PathwayBrowser/#/R-CFA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Canis familiaris 8005 R-CFA-6799981 https://reactome.org/PathwayBrowser/#/R-CFA-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Canis familiaris 8005 R-CFA-6801808 https://reactome.org/PathwayBrowser/#/R-CFA-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Canis familiaris 8005 R-DME-6789072 https://reactome.org/PathwayBrowser/#/R-DME-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Drosophila melanogaster 8005 R-DME-6799959 https://reactome.org/PathwayBrowser/#/R-DME-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Drosophila melanogaster 8005 R-DME-6799977 https://reactome.org/PathwayBrowser/#/R-DME-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Drosophila melanogaster 8005 R-DME-6799981 https://reactome.org/PathwayBrowser/#/R-DME-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Drosophila melanogaster 8005 R-DME-6801808 https://reactome.org/PathwayBrowser/#/R-DME-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Drosophila melanogaster 8005 R-DRE-6789072 https://reactome.org/PathwayBrowser/#/R-DRE-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Danio rerio 8005 R-DRE-6799959 https://reactome.org/PathwayBrowser/#/R-DRE-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Danio rerio 8005 R-DRE-6799977 https://reactome.org/PathwayBrowser/#/R-DRE-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Danio rerio 8005 R-DRE-6799981 https://reactome.org/PathwayBrowser/#/R-DRE-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Danio rerio 8005 R-DRE-6803063 https://reactome.org/PathwayBrowser/#/R-DRE-6803063 RNASEs bind bacterial LPS, PGN IEA Danio rerio 8005 R-GGA-433864 https://reactome.org/PathwayBrowser/#/R-GGA-433864 IRAK2 binds to the IRAK4 accociated with the complex of the activated TLR : TIRAP : MyD88 IEA Gallus gallus 8005 R-GGA-433961 https://reactome.org/PathwayBrowser/#/R-GGA-433961 Activated TLR homo- or heterodimer recruits adaptors TIRAP(or MAL) and MyD88 IEA Gallus gallus 8005 R-GGA-434018 https://reactome.org/PathwayBrowser/#/R-GGA-434018 Autophosphorylation of chicken IRAK4 IEA Gallus gallus 8005 R-GGA-434047 https://reactome.org/PathwayBrowser/#/R-GGA-434047 phosphorylation of IRAK2 by activated IRAK4 IEA Gallus gallus 8005 R-GGA-434053 https://reactome.org/PathwayBrowser/#/R-GGA-434053 TRAF6 binds to p-IRAK2 complexed with activated TLR IEA Gallus gallus 8005 R-GGA-434073 https://reactome.org/PathwayBrowser/#/R-GGA-434073 IRAK4 recruitment to the activated TLR complexed with ligand, TIRAP and MyD88 IEA Gallus gallus 8005 R-GGA-434084 https://reactome.org/PathwayBrowser/#/R-GGA-434084 p-IRAK2- TRAF6 dissociates from the activated chTLR complex IEA Gallus gallus 8005 R-GGA-517850 https://reactome.org/PathwayBrowser/#/R-GGA-517850 TLR2-1 : TLR1-2 heterodimer binds to its ligand TAS Gallus gallus 8005 R-GGA-6799977 https://reactome.org/PathwayBrowser/#/R-GGA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Gallus gallus 8005 R-GGA-6799981 https://reactome.org/PathwayBrowser/#/R-GGA-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Gallus gallus 8005 R-GGA-6803063 https://reactome.org/PathwayBrowser/#/R-GGA-6803063 RNASEs bind bacterial LPS, PGN IEA Gallus gallus 8005 R-HSA-166072 https://reactome.org/PathwayBrowser/#/R-HSA-166072 MyD88 forms a complex with TIRAP:activated TLR2/4 TAS Homo sapiens 8005 R-HSA-166082 https://reactome.org/PathwayBrowser/#/R-HSA-166082 IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex TAS Homo sapiens 8005 R-HSA-166091 https://reactome.org/PathwayBrowser/#/R-HSA-166091 IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex TAS Homo sapiens 8005 R-HSA-166119 https://reactome.org/PathwayBrowser/#/R-HSA-166119 First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal TAS Homo sapiens 8005 R-HSA-166284 https://reactome.org/PathwayBrowser/#/R-HSA-166284 Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP TAS Homo sapiens 8005 R-HSA-166286 https://reactome.org/PathwayBrowser/#/R-HSA-166286 Multiple IRAK1 autophosphorylation steps TAS Homo sapiens 8005 R-HSA-166362 https://reactome.org/PathwayBrowser/#/R-HSA-166362 Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 8005 R-HSA-166363 https://reactome.org/PathwayBrowser/#/R-HSA-166363 TRAF6 binds to hp- IRAK1 TAS Homo sapiens 8005 R-HSA-168950 https://reactome.org/PathwayBrowser/#/R-HSA-168950 TLR6:TLR2 is recruited to ligand:CD14:CD36 TAS Homo sapiens 8005 R-HSA-2201316 https://reactome.org/PathwayBrowser/#/R-HSA-2201316 Activated TLR2/4 interacts with MAL (TIRAP) TAS Homo sapiens 8005 R-HSA-2201322 https://reactome.org/PathwayBrowser/#/R-HSA-2201322 TIRAP is phosphorylated by BTK TAS Homo sapiens 8005 R-HSA-2262775 https://reactome.org/PathwayBrowser/#/R-HSA-2262775 Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex TAS Homo sapiens 8005 R-HSA-2262777 https://reactome.org/PathwayBrowser/#/R-HSA-2262777 TRAF6 binds to p-IRAK2 TAS Homo sapiens 8005 R-HSA-2559414 https://reactome.org/PathwayBrowser/#/R-HSA-2559414 Activated TLR2/4:TIRAP interacts with BTK TAS Homo sapiens 8005 R-HSA-2559464 https://reactome.org/PathwayBrowser/#/R-HSA-2559464 TLR6/2 ligand associates with CD14 and CD36 within lipid rafts TAS Homo sapiens 8005 R-HSA-5602353 https://reactome.org/PathwayBrowser/#/R-HSA-5602353 Defective IRAK4 variants do not bind MyD88:MAL:BTK:activated TLR2/4 TAS Homo sapiens 8005 R-HSA-5602383 https://reactome.org/PathwayBrowser/#/R-HSA-5602383 Defective MyD88 does not oligomerize within the activated TLR2/4 complex TAS Homo sapiens 8005 R-HSA-5602606 https://reactome.org/PathwayBrowser/#/R-HSA-5602606 Defective MyD88 does not bind MAL(TIRAP):TLR2/4 TAS Homo sapiens 8005 R-HSA-5602672 https://reactome.org/PathwayBrowser/#/R-HSA-5602672 Defective IRAK4 does not bind MyD88 within the TLR2/4 complex TAS Homo sapiens 8005 R-HSA-6789072 https://reactome.org/PathwayBrowser/#/R-HSA-6789072 PGLYRP1 binds bacterial peptidoglycan TAS Homo sapiens 8005 R-HSA-6789185 https://reactome.org/PathwayBrowser/#/R-HSA-6789185 Chloride ion and N-acyl group react to chloramide TAS Homo sapiens 8005 R-HSA-6789208 https://reactome.org/PathwayBrowser/#/R-HSA-6789208 HOCl-induced glycosaminoglycan fragmentation TAS Homo sapiens 8005 R-HSA-6799959 https://reactome.org/PathwayBrowser/#/R-HSA-6799959 PGLYRP3,4 binds bacterial peptidoglycan TAS Homo sapiens 8005 R-HSA-6799977 https://reactome.org/PathwayBrowser/#/R-HSA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan TAS Homo sapiens 8005 R-HSA-6799981 https://reactome.org/PathwayBrowser/#/R-HSA-6799981 PGLYRP2 binds bacterial peptidoglycan TAS Homo sapiens 8005 R-HSA-6801808 https://reactome.org/PathwayBrowser/#/R-HSA-6801808 REG3A,REG3G binds bacterial peptidoglycan TAS Homo sapiens 8005 R-HSA-6803063 https://reactome.org/PathwayBrowser/#/R-HSA-6803063 RNASEs bind bacterial LPS, PGN TAS Homo sapiens 8005 R-HSA-8863895 https://reactome.org/PathwayBrowser/#/R-HSA-8863895 IKKB phosphorylates SNAP23 TAS Homo sapiens 8005 R-HSA-937022 https://reactome.org/PathwayBrowser/#/R-HSA-937022 IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP TAS Homo sapiens 8005 R-HSA-937059 https://reactome.org/PathwayBrowser/#/R-HSA-937059 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex TAS Homo sapiens 8005 R-HSA-937079 https://reactome.org/PathwayBrowser/#/R-HSA-937079 MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 TAS Homo sapiens 8005 R-MMU-6789072 https://reactome.org/PathwayBrowser/#/R-MMU-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Mus musculus 8005 R-MMU-6799959 https://reactome.org/PathwayBrowser/#/R-MMU-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Mus musculus 8005 R-MMU-6799977 https://reactome.org/PathwayBrowser/#/R-MMU-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Mus musculus 8005 R-MMU-6799981 https://reactome.org/PathwayBrowser/#/R-MMU-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Mus musculus 8005 R-MMU-6801808 https://reactome.org/PathwayBrowser/#/R-MMU-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Mus musculus 8005 R-MMU-6803063 https://reactome.org/PathwayBrowser/#/R-MMU-6803063 RNASEs bind bacterial LPS, PGN IEA Mus musculus 8005 R-MMU-8878599 https://reactome.org/PathwayBrowser/#/R-MMU-8878599 Ssc5d binds ligands TAS Mus musculus 8005 R-RNO-6789072 https://reactome.org/PathwayBrowser/#/R-RNO-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Rattus norvegicus 8005 R-RNO-6799959 https://reactome.org/PathwayBrowser/#/R-RNO-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Rattus norvegicus 8005 R-RNO-6799977 https://reactome.org/PathwayBrowser/#/R-RNO-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Rattus norvegicus 8005 R-RNO-6799981 https://reactome.org/PathwayBrowser/#/R-RNO-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Rattus norvegicus 8005 R-RNO-6801808 https://reactome.org/PathwayBrowser/#/R-RNO-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Rattus norvegicus 8005 R-RNO-6803063 https://reactome.org/PathwayBrowser/#/R-RNO-6803063 RNASEs bind bacterial LPS, PGN IEA Rattus norvegicus 8005 R-SSC-6789072 https://reactome.org/PathwayBrowser/#/R-SSC-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Sus scrofa 8005 R-SSC-6799959 https://reactome.org/PathwayBrowser/#/R-SSC-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Sus scrofa 8005 R-SSC-6799977 https://reactome.org/PathwayBrowser/#/R-SSC-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Sus scrofa 8005 R-SSC-6799981 https://reactome.org/PathwayBrowser/#/R-SSC-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Sus scrofa 8005 R-SSC-6801808 https://reactome.org/PathwayBrowser/#/R-SSC-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Sus scrofa 8005 R-SSC-6803063 https://reactome.org/PathwayBrowser/#/R-SSC-6803063 RNASEs bind bacterial LPS, PGN IEA Sus scrofa 8005 R-XTR-6789072 https://reactome.org/PathwayBrowser/#/R-XTR-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Xenopus tropicalis 8005 R-XTR-6799959 https://reactome.org/PathwayBrowser/#/R-XTR-6799959 PGLYRP3,4 binds bacterial peptidoglycan IEA Xenopus tropicalis 8005 R-XTR-6799977 https://reactome.org/PathwayBrowser/#/R-XTR-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Xenopus tropicalis 8005 R-XTR-6799981 https://reactome.org/PathwayBrowser/#/R-XTR-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Xenopus tropicalis 8005 R-XTR-6801808 https://reactome.org/PathwayBrowser/#/R-XTR-6801808 REG3A,REG3G binds bacterial peptidoglycan IEA Xenopus tropicalis 8024 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 8024 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 8024 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 8024 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 8024 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 8024 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 8024 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 8024 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 8024 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 8024 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 8024 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 8024 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 8050 R-BTA-5689000 https://reactome.org/PathwayBrowser/#/R-BTA-5689000 AADAC deacetylates PHEN IEA Bos taurus 8050 R-CEL-5689000 https://reactome.org/PathwayBrowser/#/R-CEL-5689000 AADAC deacetylates PHEN IEA Caenorhabditis elegans 8050 R-CFA-5689000 https://reactome.org/PathwayBrowser/#/R-CFA-5689000 AADAC deacetylates PHEN IEA Canis familiaris 8050 R-DDI-5689000 https://reactome.org/PathwayBrowser/#/R-DDI-5689000 AADAC deacetylates PHEN IEA Dictyostelium discoideum 8050 R-GGA-5689000 https://reactome.org/PathwayBrowser/#/R-GGA-5689000 AADAC deacetylates PHEN IEA Gallus gallus 8050 R-HSA-5689000 https://reactome.org/PathwayBrowser/#/R-HSA-5689000 AADAC deacetylates PHEN TAS Homo sapiens 8050 R-MMU-5689000 https://reactome.org/PathwayBrowser/#/R-MMU-5689000 AADAC deacetylates PHEN IEA Mus musculus 8050 R-RNO-5689000 https://reactome.org/PathwayBrowser/#/R-RNO-5689000 AADAC deacetylates PHEN IEA Rattus norvegicus 8050 R-SPO-5689000 https://reactome.org/PathwayBrowser/#/R-SPO-5689000 AADAC deacetylates PHEN IEA Schizosaccharomyces pombe 8050 R-SSC-5689000 https://reactome.org/PathwayBrowser/#/R-SSC-5689000 AADAC deacetylates PHEN IEA Sus scrofa 80608 R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 80608 R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 80608 R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 80608 R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 80608 R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 80608 R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 80608 R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 80608 R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 80608 R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 80608 R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 80608 R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 80612 R-BTA-9750617 https://reactome.org/PathwayBrowser/#/R-BTA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 80612 R-CEL-9750617 https://reactome.org/PathwayBrowser/#/R-CEL-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 80612 R-CFA-9750617 https://reactome.org/PathwayBrowser/#/R-CFA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 80612 R-DRE-9750617 https://reactome.org/PathwayBrowser/#/R-DRE-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 80612 R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 80612 R-HSA-9750617 https://reactome.org/PathwayBrowser/#/R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 80612 R-MMU-9750617 https://reactome.org/PathwayBrowser/#/R-MMU-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 80612 R-RNO-9750617 https://reactome.org/PathwayBrowser/#/R-RNO-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 80612 R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 80612 R-XTR-9750617 https://reactome.org/PathwayBrowser/#/R-XTR-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Xenopus tropicalis 80613 R-BTA-9750546 https://reactome.org/PathwayBrowser/#/R-BTA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 80613 R-BTA-9750617 https://reactome.org/PathwayBrowser/#/R-BTA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 80613 R-CEL-9750546 https://reactome.org/PathwayBrowser/#/R-CEL-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 80613 R-CEL-9750617 https://reactome.org/PathwayBrowser/#/R-CEL-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 80613 R-CFA-9750546 https://reactome.org/PathwayBrowser/#/R-CFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 80613 R-CFA-9750617 https://reactome.org/PathwayBrowser/#/R-CFA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 80613 R-DDI-9750546 https://reactome.org/PathwayBrowser/#/R-DDI-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Dictyostelium discoideum 80613 R-DME-9750546 https://reactome.org/PathwayBrowser/#/R-DME-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Drosophila melanogaster 80613 R-DRE-9750546 https://reactome.org/PathwayBrowser/#/R-DRE-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 80613 R-DRE-9750617 https://reactome.org/PathwayBrowser/#/R-DRE-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 80613 R-GGA-9750546 https://reactome.org/PathwayBrowser/#/R-GGA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 80613 R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 80613 R-HSA-9750546 https://reactome.org/PathwayBrowser/#/R-HSA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 80613 R-HSA-9750617 https://reactome.org/PathwayBrowser/#/R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 80613 R-MMU-9750546 https://reactome.org/PathwayBrowser/#/R-MMU-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 80613 R-MMU-9750617 https://reactome.org/PathwayBrowser/#/R-MMU-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 80613 R-PFA-9750546 https://reactome.org/PathwayBrowser/#/R-PFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Plasmodium falciparum 80613 R-RNO-9750546 https://reactome.org/PathwayBrowser/#/R-RNO-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 80613 R-RNO-9750617 https://reactome.org/PathwayBrowser/#/R-RNO-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 80613 R-SSC-9750546 https://reactome.org/PathwayBrowser/#/R-SSC-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 80613 R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 80613 R-XTR-9750617 https://reactome.org/PathwayBrowser/#/R-XTR-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Xenopus tropicalis 8066 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 8066 R-BTA-9026967 https://reactome.org/PathwayBrowser/#/R-BTA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Bos taurus 8066 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 8066 R-CFA-9026967 https://reactome.org/PathwayBrowser/#/R-CFA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Canis familiaris 8066 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 8066 R-DME-9026967 https://reactome.org/PathwayBrowser/#/R-DME-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Drosophila melanogaster 8066 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 8066 R-HSA-9026967 https://reactome.org/PathwayBrowser/#/R-HSA-9026967 VKORC1 inhibitors binds VKORC1 dimer TAS Homo sapiens 8066 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 8066 R-MMU-9026967 https://reactome.org/PathwayBrowser/#/R-MMU-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Mus musculus 8066 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 8066 R-RNO-9026967 https://reactome.org/PathwayBrowser/#/R-RNO-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Rattus norvegicus 8066 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 8066 R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa 8066 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 8066 R-XTR-9026967 https://reactome.org/PathwayBrowser/#/R-XTR-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Xenopus tropicalis 8082 R-BTA-177157 https://reactome.org/PathwayBrowser/#/R-BTA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Bos taurus 8082 R-CFA-177157 https://reactome.org/PathwayBrowser/#/R-CFA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Canis familiaris 8082 R-DRE-177157 https://reactome.org/PathwayBrowser/#/R-DRE-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Danio rerio 8082 R-GGA-177157 https://reactome.org/PathwayBrowser/#/R-GGA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Gallus gallus 8082 R-HSA-177157 https://reactome.org/PathwayBrowser/#/R-HSA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate TAS Homo sapiens 8082 R-MMU-177157 https://reactome.org/PathwayBrowser/#/R-MMU-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Mus musculus 8082 R-RNO-177157 https://reactome.org/PathwayBrowser/#/R-RNO-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Rattus norvegicus 8082 R-SSC-177157 https://reactome.org/PathwayBrowser/#/R-SSC-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Sus scrofa 8082 R-XTR-177157 https://reactome.org/PathwayBrowser/#/R-XTR-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Xenopus tropicalis 8093 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 8093 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 8093 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 8093 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 8093 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 8093 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 8093 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 8093 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 8093 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 8093 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 8093 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 8093 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 8093 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 8093 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 8093 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 8093 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 8093 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 8093 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 8093 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 8093 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 8093 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 8093 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 81005 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 81005 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 81005 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 81005 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 81005 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 81005 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 81005 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 81005 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 81005 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 81005 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 81005 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 81005 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 81005 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 81005 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 81005 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 81005 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 81005 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 81005 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 81005 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 81005 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 81005 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 81005 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 81005 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 81005 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 81005 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 81005 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 81005 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 81005 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 81005 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 81005 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 81005 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 81005 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 81005 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 81007 R-SCE-6787385 https://reactome.org/PathwayBrowser/#/R-SCE-6787385 SLM3 (MTO2, MTU1) transfers a sulfur atom to 5-carboxymethylaminomethyluridine-34 in tRNA TAS Saccharomyces cerevisiae 8107 R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 8107 R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 8107 R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 8107 R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 8107 R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 8107 R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 8107 R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 8107 R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 8107 R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 81392 R-HSA-5662904 https://reactome.org/PathwayBrowser/#/R-HSA-5662904 CD isomers transform to BT, BTCA, BZ, ODHBT TAS Homo sapiens 81392 R-HSA-5662908 https://reactome.org/PathwayBrowser/#/R-HSA-5662908 Dopaquinone, cysteine form CD isomers TAS Homo sapiens 81394 R-BTA-8878581 https://reactome.org/PathwayBrowser/#/R-BTA-8878581 TYRP1 oxidises DHICA to IQCA IEA Bos taurus 81394 R-CEL-8878581 https://reactome.org/PathwayBrowser/#/R-CEL-8878581 TYRP1 oxidises DHICA to IQCA IEA Caenorhabditis elegans 81394 R-CFA-8878581 https://reactome.org/PathwayBrowser/#/R-CFA-8878581 TYRP1 oxidises DHICA to IQCA IEA Canis familiaris 81394 R-DDI-8878581 https://reactome.org/PathwayBrowser/#/R-DDI-8878581 TYRP1 oxidises DHICA to IQCA IEA Dictyostelium discoideum 81394 R-DRE-8878581 https://reactome.org/PathwayBrowser/#/R-DRE-8878581 TYRP1 oxidises DHICA to IQCA IEA Danio rerio 81394 R-GGA-8878581 https://reactome.org/PathwayBrowser/#/R-GGA-8878581 TYRP1 oxidises DHICA to IQCA IEA Gallus gallus 81394 R-HSA-8878581 https://reactome.org/PathwayBrowser/#/R-HSA-8878581 TYRP1 oxidises DHICA to IQCA TAS Homo sapiens 81394 R-MMU-8878581 https://reactome.org/PathwayBrowser/#/R-MMU-8878581 TYRP1 oxidises DHICA to IQCA IEA Mus musculus 81394 R-RNO-8878581 https://reactome.org/PathwayBrowser/#/R-RNO-8878581 TYRP1 oxidises DHICA to IQCA IEA Rattus norvegicus 81394 R-SSC-8878581 https://reactome.org/PathwayBrowser/#/R-SSC-8878581 TYRP1 oxidises DHICA to IQCA IEA Sus scrofa 81394 R-XTR-8878581 https://reactome.org/PathwayBrowser/#/R-XTR-8878581 TYRP1 oxidises DHICA to IQCA IEA Xenopus tropicalis 81559 R-BTA-8862700 https://reactome.org/PathwayBrowser/#/R-BTA-8862700 CMKLR1 binds Resolvin E1 IEA Bos taurus 81559 R-BTA-9018877 https://reactome.org/PathwayBrowser/#/R-BTA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Bos taurus 81559 R-CEL-9018877 https://reactome.org/PathwayBrowser/#/R-CEL-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Caenorhabditis elegans 81559 R-CFA-8862700 https://reactome.org/PathwayBrowser/#/R-CFA-8862700 CMKLR1 binds Resolvin E1 IEA Canis familiaris 81559 R-CFA-9018877 https://reactome.org/PathwayBrowser/#/R-CFA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Canis familiaris 81559 R-DDI-9018877 https://reactome.org/PathwayBrowser/#/R-DDI-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Dictyostelium discoideum 81559 R-DME-9018877 https://reactome.org/PathwayBrowser/#/R-DME-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Drosophila melanogaster 81559 R-DRE-9018877 https://reactome.org/PathwayBrowser/#/R-DRE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Danio rerio 81559 R-GGA-8862700 https://reactome.org/PathwayBrowser/#/R-GGA-8862700 CMKLR1 binds Resolvin E1 IEA Gallus gallus 81559 R-GGA-9018877 https://reactome.org/PathwayBrowser/#/R-GGA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Gallus gallus 81559 R-HSA-8862700 https://reactome.org/PathwayBrowser/#/R-HSA-8862700 CMKLR1 binds Resolvin E1 TAS Homo sapiens 81559 R-HSA-9018877 https://reactome.org/PathwayBrowser/#/R-HSA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 TAS Homo sapiens 81559 R-HSA-9023983 https://reactome.org/PathwayBrowser/#/R-HSA-9023983 18(R)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 81559 R-MMU-8862700 https://reactome.org/PathwayBrowser/#/R-MMU-8862700 CMKLR1 binds Resolvin E1 IEA Mus musculus 81559 R-MMU-9018877 https://reactome.org/PathwayBrowser/#/R-MMU-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Mus musculus 81559 R-RNO-8862700 https://reactome.org/PathwayBrowser/#/R-RNO-8862700 CMKLR1 binds Resolvin E1 IEA Rattus norvegicus 81559 R-RNO-9018877 https://reactome.org/PathwayBrowser/#/R-RNO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Rattus norvegicus 81559 R-SCE-9018877 https://reactome.org/PathwayBrowser/#/R-SCE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Saccharomyces cerevisiae 81559 R-SPO-9018877 https://reactome.org/PathwayBrowser/#/R-SPO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Schizosaccharomyces pombe 81559 R-SSC-8862700 https://reactome.org/PathwayBrowser/#/R-SSC-8862700 CMKLR1 binds Resolvin E1 IEA Sus scrofa 81559 R-SSC-9018877 https://reactome.org/PathwayBrowser/#/R-SSC-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Sus scrofa 81559 R-XTR-8862700 https://reactome.org/PathwayBrowser/#/R-XTR-8862700 CMKLR1 binds Resolvin E1 IEA Xenopus tropicalis 81559 R-XTR-9018877 https://reactome.org/PathwayBrowser/#/R-XTR-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Xenopus tropicalis 81560 R-HSA-9018901 https://reactome.org/PathwayBrowser/#/R-HSA-9018901 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HpEPE to 18(R)-RvE2 TAS Homo sapiens 81560 R-HSA-9023983 https://reactome.org/PathwayBrowser/#/R-HSA-9023983 18(R)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 81563 R-BTA-9018863 https://reactome.org/PathwayBrowser/#/R-BTA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Bos taurus 81563 R-BTA-9018895 https://reactome.org/PathwayBrowser/#/R-BTA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Bos taurus 81563 R-BTA-9018907 https://reactome.org/PathwayBrowser/#/R-BTA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Bos taurus 81563 R-CEL-9018895 https://reactome.org/PathwayBrowser/#/R-CEL-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Caenorhabditis elegans 81563 R-CFA-9018863 https://reactome.org/PathwayBrowser/#/R-CFA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Canis familiaris 81563 R-CFA-9018895 https://reactome.org/PathwayBrowser/#/R-CFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Canis familiaris 81563 R-CFA-9018907 https://reactome.org/PathwayBrowser/#/R-CFA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Canis familiaris 81563 R-DDI-9018863 https://reactome.org/PathwayBrowser/#/R-DDI-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Dictyostelium discoideum 81563 R-DDI-9018907 https://reactome.org/PathwayBrowser/#/R-DDI-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Dictyostelium discoideum 81563 R-DRE-9018863 https://reactome.org/PathwayBrowser/#/R-DRE-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Danio rerio 81563 R-DRE-9018907 https://reactome.org/PathwayBrowser/#/R-DRE-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Danio rerio 81563 R-GGA-9018863 https://reactome.org/PathwayBrowser/#/R-GGA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Gallus gallus 81563 R-GGA-9018895 https://reactome.org/PathwayBrowser/#/R-GGA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Gallus gallus 81563 R-HSA-9018863 https://reactome.org/PathwayBrowser/#/R-HSA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE TAS Homo sapiens 81563 R-HSA-9018895 https://reactome.org/PathwayBrowser/#/R-HSA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE TAS Homo sapiens 81563 R-HSA-9018907 https://reactome.org/PathwayBrowser/#/R-HSA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 TAS Homo sapiens 81563 R-MMU-9018863 https://reactome.org/PathwayBrowser/#/R-MMU-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Mus musculus 81563 R-MMU-9018895 https://reactome.org/PathwayBrowser/#/R-MMU-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Mus musculus 81563 R-MMU-9018907 https://reactome.org/PathwayBrowser/#/R-MMU-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Mus musculus 81563 R-PFA-9018895 https://reactome.org/PathwayBrowser/#/R-PFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Plasmodium falciparum 81563 R-RNO-9018863 https://reactome.org/PathwayBrowser/#/R-RNO-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Rattus norvegicus 81563 R-RNO-9018895 https://reactome.org/PathwayBrowser/#/R-RNO-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Rattus norvegicus 81563 R-RNO-9018907 https://reactome.org/PathwayBrowser/#/R-RNO-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Rattus norvegicus 81563 R-SSC-9018863 https://reactome.org/PathwayBrowser/#/R-SSC-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Sus scrofa 81563 R-SSC-9018895 https://reactome.org/PathwayBrowser/#/R-SSC-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Sus scrofa 81563 R-SSC-9018907 https://reactome.org/PathwayBrowser/#/R-SSC-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Sus scrofa 81563 R-XTR-9018863 https://reactome.org/PathwayBrowser/#/R-XTR-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Xenopus tropicalis 81564 R-BTA-9020258 https://reactome.org/PathwayBrowser/#/R-BTA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Bos taurus 81564 R-BTA-9024766 https://reactome.org/PathwayBrowser/#/R-BTA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Bos taurus 81564 R-CEL-9020258 https://reactome.org/PathwayBrowser/#/R-CEL-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Caenorhabditis elegans 81564 R-CFA-9020258 https://reactome.org/PathwayBrowser/#/R-CFA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Canis familiaris 81564 R-CFA-9024766 https://reactome.org/PathwayBrowser/#/R-CFA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Canis familiaris 81564 R-DDI-9020258 https://reactome.org/PathwayBrowser/#/R-DDI-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Dictyostelium discoideum 81564 R-DME-9020258 https://reactome.org/PathwayBrowser/#/R-DME-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Drosophila melanogaster 81564 R-DME-9024766 https://reactome.org/PathwayBrowser/#/R-DME-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Drosophila melanogaster 81564 R-DRE-9020258 https://reactome.org/PathwayBrowser/#/R-DRE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Danio rerio 81564 R-DRE-9024766 https://reactome.org/PathwayBrowser/#/R-DRE-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Danio rerio 81564 R-GGA-9020258 https://reactome.org/PathwayBrowser/#/R-GGA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Gallus gallus 81564 R-GGA-9024766 https://reactome.org/PathwayBrowser/#/R-GGA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Gallus gallus 81564 R-HSA-9020258 https://reactome.org/PathwayBrowser/#/R-HSA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 TAS Homo sapiens 81564 R-HSA-9024766 https://reactome.org/PathwayBrowser/#/R-HSA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 TAS Homo sapiens 81564 R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 81564 R-MMU-9020258 https://reactome.org/PathwayBrowser/#/R-MMU-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Mus musculus 81564 R-MMU-9024766 https://reactome.org/PathwayBrowser/#/R-MMU-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Mus musculus 81564 R-RNO-9020258 https://reactome.org/PathwayBrowser/#/R-RNO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Rattus norvegicus 81564 R-RNO-9024766 https://reactome.org/PathwayBrowser/#/R-RNO-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Rattus norvegicus 81564 R-SCE-9020258 https://reactome.org/PathwayBrowser/#/R-SCE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Saccharomyces cerevisiae 81564 R-SPO-9020258 https://reactome.org/PathwayBrowser/#/R-SPO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Schizosaccharomyces pombe 81564 R-SSC-9020258 https://reactome.org/PathwayBrowser/#/R-SSC-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Sus scrofa 81564 R-SSC-9024766 https://reactome.org/PathwayBrowser/#/R-SSC-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Sus scrofa 81564 R-XTR-9020258 https://reactome.org/PathwayBrowser/#/R-XTR-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Xenopus tropicalis 81564 R-XTR-9024766 https://reactome.org/PathwayBrowser/#/R-XTR-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Xenopus tropicalis 81565 R-BTA-9020258 https://reactome.org/PathwayBrowser/#/R-BTA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Bos taurus 81565 R-CEL-9020258 https://reactome.org/PathwayBrowser/#/R-CEL-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Caenorhabditis elegans 81565 R-CFA-9020258 https://reactome.org/PathwayBrowser/#/R-CFA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Canis familiaris 81565 R-DDI-9020258 https://reactome.org/PathwayBrowser/#/R-DDI-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Dictyostelium discoideum 81565 R-DME-9020258 https://reactome.org/PathwayBrowser/#/R-DME-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Drosophila melanogaster 81565 R-DRE-9020258 https://reactome.org/PathwayBrowser/#/R-DRE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Danio rerio 81565 R-GGA-9020258 https://reactome.org/PathwayBrowser/#/R-GGA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Gallus gallus 81565 R-HSA-9020258 https://reactome.org/PathwayBrowser/#/R-HSA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 TAS Homo sapiens 81565 R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 81565 R-MMU-9020258 https://reactome.org/PathwayBrowser/#/R-MMU-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Mus musculus 81565 R-RNO-9020258 https://reactome.org/PathwayBrowser/#/R-RNO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Rattus norvegicus 81565 R-SCE-9020258 https://reactome.org/PathwayBrowser/#/R-SCE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Saccharomyces cerevisiae 81565 R-SPO-9020258 https://reactome.org/PathwayBrowser/#/R-SPO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Schizosaccharomyces pombe 81565 R-SSC-9020258 https://reactome.org/PathwayBrowser/#/R-SSC-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Sus scrofa 81565 R-XTR-9020258 https://reactome.org/PathwayBrowser/#/R-XTR-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Xenopus tropicalis 81621 R-BTA-5694077 https://reactome.org/PathwayBrowser/#/R-BTA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Bos taurus 81621 R-CEL-5694077 https://reactome.org/PathwayBrowser/#/R-CEL-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Caenorhabditis elegans 81621 R-CFA-5694077 https://reactome.org/PathwayBrowser/#/R-CFA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Canis familiaris 81621 R-DME-5694077 https://reactome.org/PathwayBrowser/#/R-DME-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Drosophila melanogaster 81621 R-GGA-5694077 https://reactome.org/PathwayBrowser/#/R-GGA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Gallus gallus 81621 R-HSA-5694077 https://reactome.org/PathwayBrowser/#/R-HSA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD TAS Homo sapiens 81621 R-MMU-5694077 https://reactome.org/PathwayBrowser/#/R-MMU-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Mus musculus 81621 R-RNO-5694077 https://reactome.org/PathwayBrowser/#/R-RNO-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Rattus norvegicus 81621 R-SSC-5694077 https://reactome.org/PathwayBrowser/#/R-SSC-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Sus scrofa 81626 R-BTA-5692232 https://reactome.org/PathwayBrowser/#/R-BTA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Bos taurus 81626 R-CEL-5692232 https://reactome.org/PathwayBrowser/#/R-CEL-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Caenorhabditis elegans 81626 R-CFA-5692232 https://reactome.org/PathwayBrowser/#/R-CFA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Canis familiaris 81626 R-DDI-5692232 https://reactome.org/PathwayBrowser/#/R-DDI-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Dictyostelium discoideum 81626 R-DME-5692232 https://reactome.org/PathwayBrowser/#/R-DME-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Drosophila melanogaster 81626 R-DRE-5692232 https://reactome.org/PathwayBrowser/#/R-DRE-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Danio rerio 81626 R-GGA-5692232 https://reactome.org/PathwayBrowser/#/R-GGA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Gallus gallus 81626 R-HSA-5692232 https://reactome.org/PathwayBrowser/#/R-HSA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione TAS Homo sapiens 81626 R-MMU-5692232 https://reactome.org/PathwayBrowser/#/R-MMU-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Mus musculus 81626 R-RNO-5692232 https://reactome.org/PathwayBrowser/#/R-RNO-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Rattus norvegicus 81626 R-SCE-5692232 https://reactome.org/PathwayBrowser/#/R-SCE-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Saccharomyces cerevisiae 81626 R-SPO-5692232 https://reactome.org/PathwayBrowser/#/R-SPO-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Schizosaccharomyces pombe 81626 R-SSC-5692232 https://reactome.org/PathwayBrowser/#/R-SSC-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Sus scrofa 81626 R-XTR-5692232 https://reactome.org/PathwayBrowser/#/R-XTR-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Xenopus tropicalis 8206 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 8206 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 8206 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 8206 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 8206 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 8206 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 8206 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 8206 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 8206 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 8206 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 8206 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 8206 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 8206 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 8206 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 8206 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 8206 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 8206 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 8206 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 8206 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 8206 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 8206 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 8206 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 8206 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 8206 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 8206 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 8206 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 8206 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 8206 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 8206 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 8206 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 8206 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 8206 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 8206 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 8206 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 8206 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 8206 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 8206 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 8206 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 8206 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 8206 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 8206 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 8206 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 8214 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 8214 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 8214 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 8214 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 8214 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 8214 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 8214 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 8214 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 8214 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 8214 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 8214 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 8214 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 8214 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 8214 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 8214 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 8214 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 8214 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 8214 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 8214 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 8214 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 8214 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 8214 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 8214 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 8214 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 8214 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 8214 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 8214 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 8214 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 8214 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 8214 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 8214 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 8214 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 8214 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 8214 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 8214 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 8214 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 8214 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 8214 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 8214 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 8214 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 8214 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 8214 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 8214 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 8214 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 8214 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 8214 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 8214 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 82346 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 82346 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 82346 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 82346 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 82346 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 82346 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 82346 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 82346 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 82346 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 82346 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 82431 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 82431 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 82431 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 82431 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 82431 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 82431 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 82431 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 82431 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 82431 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 82431 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 82431 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 82431 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 82431 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 82431 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 82431 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 82431 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 82431 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 82431 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 82431 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 82431 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 82431 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 82431 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 82431 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 82431 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 82431 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 82431 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 82431 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 82431 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 82431 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 82431 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 82431 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 82431 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 82431 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 82431 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 82431 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 82431 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 82431 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 82431 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 82431 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 82602 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 82602 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 82602 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 82602 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 82602 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 82602 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 82602 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 82602 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 82602 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 82602 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 82602 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 82602 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 82602 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 82602 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 82602 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 82602 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 82602 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 82602 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 82602 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 82602 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 82602 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 82602 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 82602 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 82602 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 82602 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 82602 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 82602 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 82602 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 82602 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 82602 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 82602 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 82602 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 82602 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 82624 R-BTA-5621347 https://reactome.org/PathwayBrowser/#/R-BTA-5621347 PLCG2 translocates from cytosol to plasma membrane IEA Bos taurus 82624 R-BTA-5621353 https://reactome.org/PathwayBrowser/#/R-BTA-5621353 CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) IEA Bos taurus 82624 R-BTA-5621354 https://reactome.org/PathwayBrowser/#/R-BTA-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Bos taurus 82624 R-BTA-5621355 https://reactome.org/PathwayBrowser/#/R-BTA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Bos taurus 82624 R-BTA-5621363 https://reactome.org/PathwayBrowser/#/R-BTA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Bos taurus 82624 R-BTA-5621366 https://reactome.org/PathwayBrowser/#/R-BTA-5621366 SYK binds to p-Y65,Y76-FCER1G IEA Bos taurus 82624 R-BTA-5621370 https://reactome.org/PathwayBrowser/#/R-BTA-5621370 SYK autophosphorylates IEA Bos taurus 82624 R-CFA-5621347 https://reactome.org/PathwayBrowser/#/R-CFA-5621347 PLCG2 translocates from cytosol to plasma membrane IEA Canis familiaris 82624 R-CFA-5621353 https://reactome.org/PathwayBrowser/#/R-CFA-5621353 CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) IEA Canis familiaris 82624 R-CFA-5621354 https://reactome.org/PathwayBrowser/#/R-CFA-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Canis familiaris 82624 R-CFA-5621355 https://reactome.org/PathwayBrowser/#/R-CFA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Canis familiaris 82624 R-CFA-5621363 https://reactome.org/PathwayBrowser/#/R-CFA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Canis familiaris 82624 R-CFA-5621366 https://reactome.org/PathwayBrowser/#/R-CFA-5621366 SYK binds to p-Y65,Y76-FCER1G IEA Canis familiaris 82624 R-CFA-5621370 https://reactome.org/PathwayBrowser/#/R-CFA-5621370 SYK autophosphorylates IEA Canis familiaris 82624 R-DRE-5621353 https://reactome.org/PathwayBrowser/#/R-DRE-5621353 CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) IEA Danio rerio 82624 R-DRE-5621354 https://reactome.org/PathwayBrowser/#/R-DRE-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Danio rerio 82624 R-DRE-5621355 https://reactome.org/PathwayBrowser/#/R-DRE-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Danio rerio 82624 R-HSA-5621347 https://reactome.org/PathwayBrowser/#/R-HSA-5621347 PLCG2 translocates from cytosol to plasma membrane TAS Homo sapiens 82624 R-HSA-5621353 https://reactome.org/PathwayBrowser/#/R-HSA-5621353 CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) TAS Homo sapiens 82624 R-HSA-5621354 https://reactome.org/PathwayBrowser/#/R-HSA-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate TAS Homo sapiens 82624 R-HSA-5621355 https://reactome.org/PathwayBrowser/#/R-HSA-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG TAS Homo sapiens 82624 R-HSA-5621356 https://reactome.org/PathwayBrowser/#/R-HSA-5621356 PLCG1 binds p-6Y-SYK:p-Y65,Y76-FCER1G IEA Homo sapiens 82624 R-HSA-5621363 https://reactome.org/PathwayBrowser/#/R-HSA-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 TAS Homo sapiens 82624 R-HSA-5621366 https://reactome.org/PathwayBrowser/#/R-HSA-5621366 SYK binds to p-Y65,Y76-FCER1G TAS Homo sapiens 82624 R-HSA-5621370 https://reactome.org/PathwayBrowser/#/R-HSA-5621370 SYK autophosphorylates TAS Homo sapiens 82624 R-MMU-5621347 https://reactome.org/PathwayBrowser/#/R-MMU-5621347 PLCG2 translocates from cytosol to plasma membrane IEA Mus musculus 82624 R-MMU-5621353 https://reactome.org/PathwayBrowser/#/R-MMU-5621353 CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) IEA Mus musculus 82624 R-MMU-5621354 https://reactome.org/PathwayBrowser/#/R-MMU-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Mus musculus 82624 R-MMU-5621355 https://reactome.org/PathwayBrowser/#/R-MMU-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Mus musculus 82624 R-MMU-5621363 https://reactome.org/PathwayBrowser/#/R-MMU-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Mus musculus 82624 R-MMU-5621366 https://reactome.org/PathwayBrowser/#/R-MMU-5621366 SYK binds to p-Y65,Y76-FCER1G IEA Mus musculus 82624 R-MMU-5621370 https://reactome.org/PathwayBrowser/#/R-MMU-5621370 SYK autophosphorylates IEA Mus musculus 82624 R-RNO-5621347 https://reactome.org/PathwayBrowser/#/R-RNO-5621347 PLCG2 translocates from cytosol to plasma membrane IEA Rattus norvegicus 82624 R-RNO-5621353 https://reactome.org/PathwayBrowser/#/R-RNO-5621353 CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) IEA Rattus norvegicus 82624 R-RNO-5621354 https://reactome.org/PathwayBrowser/#/R-RNO-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Rattus norvegicus 82624 R-RNO-5621355 https://reactome.org/PathwayBrowser/#/R-RNO-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Rattus norvegicus 82624 R-RNO-5621363 https://reactome.org/PathwayBrowser/#/R-RNO-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Rattus norvegicus 82624 R-RNO-5621366 https://reactome.org/PathwayBrowser/#/R-RNO-5621366 SYK binds to p-Y65,Y76-FCER1G IEA Rattus norvegicus 82624 R-RNO-5621370 https://reactome.org/PathwayBrowser/#/R-RNO-5621370 SYK autophosphorylates IEA Rattus norvegicus 82624 R-SSC-5621347 https://reactome.org/PathwayBrowser/#/R-SSC-5621347 PLCG2 translocates from cytosol to plasma membrane IEA Sus scrofa 82624 R-SSC-5621353 https://reactome.org/PathwayBrowser/#/R-SSC-5621353 CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) IEA Sus scrofa 82624 R-SSC-5621354 https://reactome.org/PathwayBrowser/#/R-SSC-5621354 CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate IEA Sus scrofa 82624 R-SSC-5621355 https://reactome.org/PathwayBrowser/#/R-SSC-5621355 LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG IEA Sus scrofa 82624 R-SSC-5621363 https://reactome.org/PathwayBrowser/#/R-SSC-5621363 SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 IEA Sus scrofa 82624 R-SSC-5621366 https://reactome.org/PathwayBrowser/#/R-SSC-5621366 SYK binds to p-Y65,Y76-FCER1G IEA Sus scrofa 82624 R-SSC-5621370 https://reactome.org/PathwayBrowser/#/R-SSC-5621370 SYK autophosphorylates IEA Sus scrofa 82637 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 82637 R-BTA-9845538 https://reactome.org/PathwayBrowser/#/R-BTA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Bos taurus 82637 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 82637 R-CFA-9845538 https://reactome.org/PathwayBrowser/#/R-CFA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Canis familiaris 82637 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 82637 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 82637 R-GGA-9845538 https://reactome.org/PathwayBrowser/#/R-GGA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Gallus gallus 82637 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 82637 R-HSA-9845538 https://reactome.org/PathwayBrowser/#/R-HSA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides TAS Homo sapiens 82637 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 82637 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 82637 R-MMU-9845538 https://reactome.org/PathwayBrowser/#/R-MMU-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Mus musculus 82637 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 82637 R-RNO-9845538 https://reactome.org/PathwayBrowser/#/R-RNO-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Rattus norvegicus 82637 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 82637 R-SSC-9845538 https://reactome.org/PathwayBrowser/#/R-SSC-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Sus scrofa 82637 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 82637 R-XTR-9845538 https://reactome.org/PathwayBrowser/#/R-XTR-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Xenopus tropicalis 82639 R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus 82639 R-BTA-1605717 https://reactome.org/PathwayBrowser/#/R-BTA-1605717 GM2A binds and mobilizes ligands IEA Bos taurus 82639 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 82639 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 82639 R-BTA-9845516 https://reactome.org/PathwayBrowser/#/R-BTA-9845516 B3GALT4 transfers Gal to gangliosides IEA Bos taurus 82639 R-BTA-9845538 https://reactome.org/PathwayBrowser/#/R-BTA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Bos taurus 82639 R-BTA-9846332 https://reactome.org/PathwayBrowser/#/R-BTA-9846332 FUT1,2 transfer fucose to gangliosides IEA Bos taurus 82639 R-CEL-1605624 https://reactome.org/PathwayBrowser/#/R-CEL-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Caenorhabditis elegans 82639 R-CEL-1605717 https://reactome.org/PathwayBrowser/#/R-CEL-1605717 GM2A binds and mobilizes ligands IEA Caenorhabditis elegans 82639 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 82639 R-CEL-9845516 https://reactome.org/PathwayBrowser/#/R-CEL-9845516 B3GALT4 transfers Gal to gangliosides IEA Caenorhabditis elegans 82639 R-CEL-9846332 https://reactome.org/PathwayBrowser/#/R-CEL-9846332 FUT1,2 transfer fucose to gangliosides IEA Caenorhabditis elegans 82639 R-CFA-1605624 https://reactome.org/PathwayBrowser/#/R-CFA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Canis familiaris 82639 R-CFA-1605717 https://reactome.org/PathwayBrowser/#/R-CFA-1605717 GM2A binds and mobilizes ligands IEA Canis familiaris 82639 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 82639 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 82639 R-CFA-9845516 https://reactome.org/PathwayBrowser/#/R-CFA-9845516 B3GALT4 transfers Gal to gangliosides IEA Canis familiaris 82639 R-CFA-9845538 https://reactome.org/PathwayBrowser/#/R-CFA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Canis familiaris 82639 R-CFA-9846332 https://reactome.org/PathwayBrowser/#/R-CFA-9846332 FUT1,2 transfer fucose to gangliosides IEA Canis familiaris 82639 R-DDI-1605624 https://reactome.org/PathwayBrowser/#/R-DDI-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Dictyostelium discoideum 82639 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 82639 R-DME-1605624 https://reactome.org/PathwayBrowser/#/R-DME-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Drosophila melanogaster 82639 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 82639 R-DME-9845516 https://reactome.org/PathwayBrowser/#/R-DME-9845516 B3GALT4 transfers Gal to gangliosides IEA Drosophila melanogaster 82639 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 82639 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus 82639 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 82639 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 82639 R-GGA-9845538 https://reactome.org/PathwayBrowser/#/R-GGA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Gallus gallus 82639 R-HSA-1605624 https://reactome.org/PathwayBrowser/#/R-HSA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 TAS Homo sapiens 82639 R-HSA-1605717 https://reactome.org/PathwayBrowser/#/R-HSA-1605717 GM2A binds and mobilizes ligands TAS Homo sapiens 82639 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 82639 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 82639 R-HSA-9840579 https://reactome.org/PathwayBrowser/#/R-HSA-9840579 GM1 localizes to ILV membrane TAS Homo sapiens 82639 R-HSA-9840581 https://reactome.org/PathwayBrowser/#/R-HSA-9840581 GM1 localizes to endosome membrane TAS Homo sapiens 82639 R-HSA-9845516 https://reactome.org/PathwayBrowser/#/R-HSA-9845516 B3GALT4 transfers Gal to gangliosides TAS Homo sapiens 82639 R-HSA-9845538 https://reactome.org/PathwayBrowser/#/R-HSA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides TAS Homo sapiens 82639 R-HSA-9846332 https://reactome.org/PathwayBrowser/#/R-HSA-9846332 FUT1,2 transfer fucose to gangliosides TAS Homo sapiens 82639 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 82639 R-MMU-1605624 https://reactome.org/PathwayBrowser/#/R-MMU-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Mus musculus 82639 R-MMU-1605717 https://reactome.org/PathwayBrowser/#/R-MMU-1605717 GM2A binds and mobilizes ligands IEA Mus musculus 82639 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 82639 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 82639 R-MMU-9845516 https://reactome.org/PathwayBrowser/#/R-MMU-9845516 B3GALT4 transfers Gal to gangliosides IEA Mus musculus 82639 R-MMU-9845538 https://reactome.org/PathwayBrowser/#/R-MMU-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Mus musculus 82639 R-MMU-9846332 https://reactome.org/PathwayBrowser/#/R-MMU-9846332 FUT1,2 transfer fucose to gangliosides IEA Mus musculus 82639 R-RNO-1605624 https://reactome.org/PathwayBrowser/#/R-RNO-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Rattus norvegicus 82639 R-RNO-1605717 https://reactome.org/PathwayBrowser/#/R-RNO-1605717 GM2A binds and mobilizes ligands IEA Rattus norvegicus 82639 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 82639 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 82639 R-RNO-9845516 https://reactome.org/PathwayBrowser/#/R-RNO-9845516 B3GALT4 transfers Gal to gangliosides IEA Rattus norvegicus 82639 R-RNO-9845538 https://reactome.org/PathwayBrowser/#/R-RNO-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Rattus norvegicus 82639 R-RNO-9846332 https://reactome.org/PathwayBrowser/#/R-RNO-9846332 FUT1,2 transfer fucose to gangliosides IEA Rattus norvegicus 82639 R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa 82639 R-SSC-1605717 https://reactome.org/PathwayBrowser/#/R-SSC-1605717 GM2A binds and mobilizes ligands IEA Sus scrofa 82639 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 82639 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 82639 R-SSC-9845516 https://reactome.org/PathwayBrowser/#/R-SSC-9845516 B3GALT4 transfers Gal to gangliosides IEA Sus scrofa 82639 R-SSC-9845538 https://reactome.org/PathwayBrowser/#/R-SSC-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Sus scrofa 82639 R-SSC-9846332 https://reactome.org/PathwayBrowser/#/R-SSC-9846332 FUT1,2 transfer fucose to gangliosides IEA Sus scrofa 82639 R-XTR-1605624 https://reactome.org/PathwayBrowser/#/R-XTR-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Xenopus tropicalis 82639 R-XTR-1605717 https://reactome.org/PathwayBrowser/#/R-XTR-1605717 GM2A binds and mobilizes ligands IEA Xenopus tropicalis 82639 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 82639 R-XTR-9845516 https://reactome.org/PathwayBrowser/#/R-XTR-9845516 B3GALT4 transfers Gal to gangliosides IEA Xenopus tropicalis 82639 R-XTR-9845538 https://reactome.org/PathwayBrowser/#/R-XTR-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Xenopus tropicalis 82639 R-XTR-9846332 https://reactome.org/PathwayBrowser/#/R-XTR-9846332 FUT1,2 transfer fucose to gangliosides IEA Xenopus tropicalis 82643 R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 82643 R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 82643 R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 82643 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 82643 R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 82643 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 82643 R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 82643 R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 82643 R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 82852 R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 82852 R-HSA-6782336 https://reactome.org/PathwayBrowser/#/R-HSA-6782336 ADAT1 deaminates adenosine-37 in tRNA(Ala) IEA Homo sapiens 82852 R-SCE-6790128 https://reactome.org/PathwayBrowser/#/R-SCE-6790128 TAD1 deaminates adenosine-37 in tRNA(Ala) yielding inosine-37 TAS Saccharomyces cerevisiae 82953 R-BTA-1605717 https://reactome.org/PathwayBrowser/#/R-BTA-1605717 GM2A binds and mobilizes ligands IEA Bos taurus 82953 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 82953 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 82953 R-BTA-9844587 https://reactome.org/PathwayBrowser/#/R-BTA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Bos taurus 82953 R-CEL-1605717 https://reactome.org/PathwayBrowser/#/R-CEL-1605717 GM2A binds and mobilizes ligands IEA Caenorhabditis elegans 82953 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 82953 R-CFA-1605717 https://reactome.org/PathwayBrowser/#/R-CFA-1605717 GM2A binds and mobilizes ligands IEA Canis familiaris 82953 R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 82953 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 82953 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 82953 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 82953 R-DRE-9844587 https://reactome.org/PathwayBrowser/#/R-DRE-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Danio rerio 82953 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 82953 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 82953 R-GGA-9844587 https://reactome.org/PathwayBrowser/#/R-GGA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Gallus gallus 82953 R-HSA-1605717 https://reactome.org/PathwayBrowser/#/R-HSA-1605717 GM2A binds and mobilizes ligands TAS Homo sapiens 82953 R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 82953 R-HSA-2396083 https://reactome.org/PathwayBrowser/#/R-HSA-2396083 Laminins bind galactosyl sulfatide and related sulfated glycolipids IEA Homo sapiens 82953 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 82953 R-HSA-9844587 https://reactome.org/PathwayBrowser/#/R-HSA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer TAS Homo sapiens 82953 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 82953 R-MMU-1605717 https://reactome.org/PathwayBrowser/#/R-MMU-1605717 GM2A binds and mobilizes ligands IEA Mus musculus 82953 R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 82953 R-MMU-2465886 https://reactome.org/PathwayBrowser/#/R-MMU-2465886 Laminin binds galactosyl sulfatide and related sulfated glycolipids TAS Mus musculus 82953 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 82953 R-MMU-9844587 https://reactome.org/PathwayBrowser/#/R-MMU-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Mus musculus 82953 R-RNO-1605717 https://reactome.org/PathwayBrowser/#/R-RNO-1605717 GM2A binds and mobilizes ligands IEA Rattus norvegicus 82953 R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 82953 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 82953 R-RNO-9844587 https://reactome.org/PathwayBrowser/#/R-RNO-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Rattus norvegicus 82953 R-SSC-1605717 https://reactome.org/PathwayBrowser/#/R-SSC-1605717 GM2A binds and mobilizes ligands IEA Sus scrofa 82953 R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 82953 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 82953 R-SSC-9844587 https://reactome.org/PathwayBrowser/#/R-SSC-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Sus scrofa 82953 R-XTR-1605717 https://reactome.org/PathwayBrowser/#/R-XTR-1605717 GM2A binds and mobilizes ligands IEA Xenopus tropicalis 82953 R-XTR-9844587 https://reactome.org/PathwayBrowser/#/R-XTR-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Xenopus tropicalis 83071 R-HSA-5389839 https://reactome.org/PathwayBrowser/#/R-HSA-5389839 39S subunit binds 28S subunit:mRNA:fMet-tRNA IEA Homo sapiens 83071 R-HSA-5389842 https://reactome.org/PathwayBrowser/#/R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome IEA Homo sapiens 83071 R-HSA-5389848 https://reactome.org/PathwayBrowser/#/R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA IEA Homo sapiens 83071 R-HSA-5389857 https://reactome.org/PathwayBrowser/#/R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) IEA Homo sapiens 83071 R-HSA-5419261 https://reactome.org/PathwayBrowser/#/R-HSA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP TAS Homo sapiens 83071 R-HSA-5419264 https://reactome.org/PathwayBrowser/#/R-HSA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA TAS Homo sapiens 83071 R-HSA-5419271 https://reactome.org/PathwayBrowser/#/R-HSA-5419271 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP TAS Homo sapiens 83071 R-HSA-5419273 https://reactome.org/PathwayBrowser/#/R-HSA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits TAS Homo sapiens 83071 R-HSA-5419277 https://reactome.org/PathwayBrowser/#/R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA TAS Homo sapiens 83071 R-HSA-5419279 https://reactome.org/PathwayBrowser/#/R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) IEA Homo sapiens 83071 R-HSA-5419281 https://reactome.org/PathwayBrowser/#/R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA TAS Homo sapiens 83071 R-HSA-5696807 https://reactome.org/PathwayBrowser/#/R-HSA-5696807 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 83071 R-HSA-5696813 https://reactome.org/PathwayBrowser/#/R-HSA-5696813 TSEN complex cleaves the intron from pre-tRNA TAS Homo sapiens 83071 R-HSA-5696816 https://reactome.org/PathwayBrowser/#/R-HSA-5696816 tRNA ligase complex ligates tRNA exons TAS Homo sapiens 83071 R-HSA-6783483 https://reactome.org/PathwayBrowser/#/R-HSA-6783483 tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol TAS Homo sapiens 83071 R-HSA-6785478 https://reactome.org/PathwayBrowser/#/R-HSA-6785478 Processed tRNA binds XPOT and RAN:GTP TAS Homo sapiens 83071 R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 83273 R-BTA-1605591 https://reactome.org/PathwayBrowser/#/R-BTA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Bos taurus 83273 R-BTA-1605797 https://reactome.org/PathwayBrowser/#/R-BTA-1605797 SMPD1 hydrolyzes SPHM IEA Bos taurus 83273 R-BTA-1606273 https://reactome.org/PathwayBrowser/#/R-BTA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Bos taurus 83273 R-BTA-1606288 https://reactome.org/PathwayBrowser/#/R-BTA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Bos taurus 83273 R-BTA-1606564 https://reactome.org/PathwayBrowser/#/R-BTA-1606564 GALC hydrolyzes GalCer IEA Bos taurus 83273 R-BTA-1606583 https://reactome.org/PathwayBrowser/#/R-BTA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Bos taurus 83273 R-BTA-1606602 https://reactome.org/PathwayBrowser/#/R-BTA-1606602 ASAH1 hydrolyzes ceramide IEA Bos taurus 83273 R-BTA-1638845 https://reactome.org/PathwayBrowser/#/R-BTA-1638845 CERK phosphorylates CERA to form C1P IEA Bos taurus 83273 R-BTA-1640164 https://reactome.org/PathwayBrowser/#/R-BTA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Bos taurus 83273 R-BTA-1861788 https://reactome.org/PathwayBrowser/#/R-BTA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Bos taurus 83273 R-BTA-1861789 https://reactome.org/PathwayBrowser/#/R-BTA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Bos taurus 83273 R-BTA-428205 https://reactome.org/PathwayBrowser/#/R-BTA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Bos taurus 83273 R-BTA-428231 https://reactome.org/PathwayBrowser/#/R-BTA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Bos taurus 83273 R-BTA-429683 https://reactome.org/PathwayBrowser/#/R-BTA-429683 CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus IEA Bos taurus 83273 R-BTA-429694 https://reactome.org/PathwayBrowser/#/R-BTA-429694 CERT1-2 complex dissociates IEA Bos taurus 83273 R-BTA-429699 https://reactome.org/PathwayBrowser/#/R-BTA-429699 CERT1-2 complex binds ceramide IEA Bos taurus 83273 R-BTA-429786 https://reactome.org/PathwayBrowser/#/R-BTA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Bos taurus 83273 R-BTA-429798 https://reactome.org/PathwayBrowser/#/R-BTA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Bos taurus 83273 R-BTA-5696358 https://reactome.org/PathwayBrowser/#/R-BTA-5696358 TREM,CD300 binds lipids IEA Bos taurus 83273 R-BTA-6785933 https://reactome.org/PathwayBrowser/#/R-BTA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Bos taurus 83273 R-CEL-1605591 https://reactome.org/PathwayBrowser/#/R-CEL-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Caenorhabditis elegans 83273 R-CEL-1605797 https://reactome.org/PathwayBrowser/#/R-CEL-1605797 SMPD1 hydrolyzes SPHM IEA Caenorhabditis elegans 83273 R-CEL-1606273 https://reactome.org/PathwayBrowser/#/R-CEL-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Caenorhabditis elegans 83273 R-CEL-1606288 https://reactome.org/PathwayBrowser/#/R-CEL-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Caenorhabditis elegans 83273 R-CEL-1606564 https://reactome.org/PathwayBrowser/#/R-CEL-1606564 GALC hydrolyzes GalCer IEA Caenorhabditis elegans 83273 R-CEL-1606602 https://reactome.org/PathwayBrowser/#/R-CEL-1606602 ASAH1 hydrolyzes ceramide IEA Caenorhabditis elegans 83273 R-CEL-1638845 https://reactome.org/PathwayBrowser/#/R-CEL-1638845 CERK phosphorylates CERA to form C1P IEA Caenorhabditis elegans 83273 R-CEL-1640164 https://reactome.org/PathwayBrowser/#/R-CEL-1640164 ENPP7 hydrolyzes sphingomyelin IEA Caenorhabditis elegans 83273 R-CEL-1861788 https://reactome.org/PathwayBrowser/#/R-CEL-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Caenorhabditis elegans 83273 R-CEL-1861789 https://reactome.org/PathwayBrowser/#/R-CEL-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Caenorhabditis elegans 83273 R-CEL-428205 https://reactome.org/PathwayBrowser/#/R-CEL-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Caenorhabditis elegans 83273 R-CEL-428231 https://reactome.org/PathwayBrowser/#/R-CEL-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Caenorhabditis elegans 83273 R-CEL-429683 https://reactome.org/PathwayBrowser/#/R-CEL-429683 CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus IEA Caenorhabditis elegans 83273 R-CEL-429786 https://reactome.org/PathwayBrowser/#/R-CEL-429786 SGMS2 transfers phosphocholine onto ceramide IEA Caenorhabditis elegans 83273 R-CEL-429798 https://reactome.org/PathwayBrowser/#/R-CEL-429798 SGMS1 transfers phosphocholine onto ceramide IEA Caenorhabditis elegans 83273 R-CEL-6785933 https://reactome.org/PathwayBrowser/#/R-CEL-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Caenorhabditis elegans 83273 R-CFA-1605591 https://reactome.org/PathwayBrowser/#/R-CFA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Canis familiaris 83273 R-CFA-1605797 https://reactome.org/PathwayBrowser/#/R-CFA-1605797 SMPD1 hydrolyzes SPHM IEA Canis familiaris 83273 R-CFA-1606273 https://reactome.org/PathwayBrowser/#/R-CFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Canis familiaris 83273 R-CFA-1606288 https://reactome.org/PathwayBrowser/#/R-CFA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Canis familiaris 83273 R-CFA-1606564 https://reactome.org/PathwayBrowser/#/R-CFA-1606564 GALC hydrolyzes GalCer IEA Canis familiaris 83273 R-CFA-1606583 https://reactome.org/PathwayBrowser/#/R-CFA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Canis familiaris 83273 R-CFA-1606602 https://reactome.org/PathwayBrowser/#/R-CFA-1606602 ASAH1 hydrolyzes ceramide IEA Canis familiaris 83273 R-CFA-1638845 https://reactome.org/PathwayBrowser/#/R-CFA-1638845 CERK phosphorylates CERA to form C1P IEA Canis familiaris 83273 R-CFA-1640164 https://reactome.org/PathwayBrowser/#/R-CFA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Canis familiaris 83273 R-CFA-1861788 https://reactome.org/PathwayBrowser/#/R-CFA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Canis familiaris 83273 R-CFA-1861789 https://reactome.org/PathwayBrowser/#/R-CFA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Canis familiaris 83273 R-CFA-428205 https://reactome.org/PathwayBrowser/#/R-CFA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Canis familiaris 83273 R-CFA-428231 https://reactome.org/PathwayBrowser/#/R-CFA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Canis familiaris 83273 R-CFA-429786 https://reactome.org/PathwayBrowser/#/R-CFA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Canis familiaris 83273 R-CFA-429798 https://reactome.org/PathwayBrowser/#/R-CFA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Canis familiaris 83273 R-CFA-5696358 https://reactome.org/PathwayBrowser/#/R-CFA-5696358 TREM,CD300 binds lipids IEA Canis familiaris 83273 R-CFA-6785933 https://reactome.org/PathwayBrowser/#/R-CFA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Canis familiaris 83273 R-DDI-1605797 https://reactome.org/PathwayBrowser/#/R-DDI-1605797 SMPD1 hydrolyzes SPHM IEA Dictyostelium discoideum 83273 R-DDI-1606273 https://reactome.org/PathwayBrowser/#/R-DDI-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Dictyostelium discoideum 83273 R-DDI-1606583 https://reactome.org/PathwayBrowser/#/R-DDI-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Dictyostelium discoideum 83273 R-DDI-1640164 https://reactome.org/PathwayBrowser/#/R-DDI-1640164 ENPP7 hydrolyzes sphingomyelin IEA Dictyostelium discoideum 83273 R-DDI-1861788 https://reactome.org/PathwayBrowser/#/R-DDI-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Dictyostelium discoideum 83273 R-DME-1605591 https://reactome.org/PathwayBrowser/#/R-DME-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Drosophila melanogaster 83273 R-DME-1605797 https://reactome.org/PathwayBrowser/#/R-DME-1605797 SMPD1 hydrolyzes SPHM IEA Drosophila melanogaster 83273 R-DME-1606273 https://reactome.org/PathwayBrowser/#/R-DME-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Drosophila melanogaster 83273 R-DME-1606288 https://reactome.org/PathwayBrowser/#/R-DME-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Drosophila melanogaster 83273 R-DME-1606583 https://reactome.org/PathwayBrowser/#/R-DME-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Drosophila melanogaster 83273 R-DME-1638845 https://reactome.org/PathwayBrowser/#/R-DME-1638845 CERK phosphorylates CERA to form C1P IEA Drosophila melanogaster 83273 R-DME-1861788 https://reactome.org/PathwayBrowser/#/R-DME-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Drosophila melanogaster 83273 R-DME-1861789 https://reactome.org/PathwayBrowser/#/R-DME-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Drosophila melanogaster 83273 R-DME-428205 https://reactome.org/PathwayBrowser/#/R-DME-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Drosophila melanogaster 83273 R-DME-428231 https://reactome.org/PathwayBrowser/#/R-DME-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Drosophila melanogaster 83273 R-DME-429683 https://reactome.org/PathwayBrowser/#/R-DME-429683 CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus IEA Drosophila melanogaster 83273 R-DME-429694 https://reactome.org/PathwayBrowser/#/R-DME-429694 CERT1-2 complex dissociates IEA Drosophila melanogaster 83273 R-DME-429699 https://reactome.org/PathwayBrowser/#/R-DME-429699 CERT1-2 complex binds ceramide IEA Drosophila melanogaster 83273 R-DRE-1606273 https://reactome.org/PathwayBrowser/#/R-DRE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Danio rerio 83273 R-DRE-1606288 https://reactome.org/PathwayBrowser/#/R-DRE-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Danio rerio 83273 R-DRE-1606583 https://reactome.org/PathwayBrowser/#/R-DRE-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Danio rerio 83273 R-DRE-1861788 https://reactome.org/PathwayBrowser/#/R-DRE-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Danio rerio 83273 R-DRE-1861789 https://reactome.org/PathwayBrowser/#/R-DRE-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Danio rerio 83273 R-DRE-428231 https://reactome.org/PathwayBrowser/#/R-DRE-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Danio rerio 83273 R-DRE-429683 https://reactome.org/PathwayBrowser/#/R-DRE-429683 CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus IEA Danio rerio 83273 R-DRE-429694 https://reactome.org/PathwayBrowser/#/R-DRE-429694 CERT1-2 complex dissociates IEA Danio rerio 83273 R-DRE-429699 https://reactome.org/PathwayBrowser/#/R-DRE-429699 CERT1-2 complex binds ceramide IEA Danio rerio 83273 R-DRE-429786 https://reactome.org/PathwayBrowser/#/R-DRE-429786 SGMS2 transfers phosphocholine onto ceramide IEA Danio rerio 83273 R-DRE-429798 https://reactome.org/PathwayBrowser/#/R-DRE-429798 SGMS1 transfers phosphocholine onto ceramide IEA Danio rerio 83273 R-DRE-5696358 https://reactome.org/PathwayBrowser/#/R-DRE-5696358 TREM,CD300 binds lipids IEA Danio rerio 83273 R-DRE-6785933 https://reactome.org/PathwayBrowser/#/R-DRE-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Danio rerio 83273 R-GGA-1605591 https://reactome.org/PathwayBrowser/#/R-GGA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Gallus gallus 83273 R-GGA-1605797 https://reactome.org/PathwayBrowser/#/R-GGA-1605797 SMPD1 hydrolyzes SPHM IEA Gallus gallus 83273 R-GGA-1606273 https://reactome.org/PathwayBrowser/#/R-GGA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Gallus gallus 83273 R-GGA-1606288 https://reactome.org/PathwayBrowser/#/R-GGA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Gallus gallus 83273 R-GGA-1606564 https://reactome.org/PathwayBrowser/#/R-GGA-1606564 GALC hydrolyzes GalCer IEA Gallus gallus 83273 R-GGA-1606583 https://reactome.org/PathwayBrowser/#/R-GGA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Gallus gallus 83273 R-GGA-1606602 https://reactome.org/PathwayBrowser/#/R-GGA-1606602 ASAH1 hydrolyzes ceramide IEA Gallus gallus 83273 R-GGA-1638845 https://reactome.org/PathwayBrowser/#/R-GGA-1638845 CERK phosphorylates CERA to form C1P IEA Gallus gallus 83273 R-GGA-1640164 https://reactome.org/PathwayBrowser/#/R-GGA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Gallus gallus 83273 R-GGA-1861788 https://reactome.org/PathwayBrowser/#/R-GGA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Gallus gallus 83273 R-GGA-428205 https://reactome.org/PathwayBrowser/#/R-GGA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Gallus gallus 83273 R-GGA-428231 https://reactome.org/PathwayBrowser/#/R-GGA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Gallus gallus 83273 R-GGA-429786 https://reactome.org/PathwayBrowser/#/R-GGA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Gallus gallus 83273 R-GGA-429798 https://reactome.org/PathwayBrowser/#/R-GGA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Gallus gallus 83273 R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 83273 R-GGA-433608 https://reactome.org/PathwayBrowser/#/R-GGA-433608 ceramide + H2O => stearate + sphingosine [endoplasmic reticulum] IEA Gallus gallus 83273 R-GGA-5696358 https://reactome.org/PathwayBrowser/#/R-GGA-5696358 TREM,CD300 binds lipids IEA Gallus gallus 83273 R-GGA-6785933 https://reactome.org/PathwayBrowser/#/R-GGA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Gallus gallus 83273 R-HSA-1605591 https://reactome.org/PathwayBrowser/#/R-HSA-1605591 GBA1:SAPC hydrolyzes GlcCer TAS Homo sapiens 83273 R-HSA-1605797 https://reactome.org/PathwayBrowser/#/R-HSA-1605797 SMPD1 hydrolyzes SPHM TAS Homo sapiens 83273 R-HSA-1606273 https://reactome.org/PathwayBrowser/#/R-HSA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) TAS Homo sapiens 83273 R-HSA-1606288 https://reactome.org/PathwayBrowser/#/R-HSA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) TAS Homo sapiens 83273 R-HSA-1606564 https://reactome.org/PathwayBrowser/#/R-HSA-1606564 GALC hydrolyzes GalCer TAS Homo sapiens 83273 R-HSA-1606583 https://reactome.org/PathwayBrowser/#/R-HSA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) TAS Homo sapiens 83273 R-HSA-1606602 https://reactome.org/PathwayBrowser/#/R-HSA-1606602 ASAH1 hydrolyzes ceramide TAS Homo sapiens 83273 R-HSA-1638845 https://reactome.org/PathwayBrowser/#/R-HSA-1638845 CERK phosphorylates CERA to form C1P TAS Homo sapiens 83273 R-HSA-1640164 https://reactome.org/PathwayBrowser/#/R-HSA-1640164 ENPP7 hydrolyzes sphingomyelin TAS Homo sapiens 83273 R-HSA-1861788 https://reactome.org/PathwayBrowser/#/R-HSA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) TAS Homo sapiens 83273 R-HSA-1861789 https://reactome.org/PathwayBrowser/#/R-HSA-1861789 GBA3 hydrolyzes GlcCer (cytosol) TAS Homo sapiens 83273 R-HSA-193706 https://reactome.org/PathwayBrowser/#/R-HSA-193706 Production of ceramide which can activate JNK and other targets IEA Homo sapiens 83273 R-HSA-428205 https://reactome.org/PathwayBrowser/#/R-HSA-428205 ACER2 hydrolyzes ceramide (Golgi) TAS Homo sapiens 83273 R-HSA-428231 https://reactome.org/PathwayBrowser/#/R-HSA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) TAS Homo sapiens 83273 R-HSA-429683 https://reactome.org/PathwayBrowser/#/R-HSA-429683 CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus TAS Homo sapiens 83273 R-HSA-429694 https://reactome.org/PathwayBrowser/#/R-HSA-429694 CERT1-2 complex dissociates TAS Homo sapiens 83273 R-HSA-429699 https://reactome.org/PathwayBrowser/#/R-HSA-429699 CERT1-2 complex binds ceramide TAS Homo sapiens 83273 R-HSA-429786 https://reactome.org/PathwayBrowser/#/R-HSA-429786 SGMS2 transfers phosphocholine onto ceramide TAS Homo sapiens 83273 R-HSA-429798 https://reactome.org/PathwayBrowser/#/R-HSA-429798 SGMS1 transfers phosphocholine onto ceramide TAS Homo sapiens 83273 R-HSA-5696358 https://reactome.org/PathwayBrowser/#/R-HSA-5696358 TREM,CD300 binds lipids TAS Homo sapiens 83273 R-HSA-6785933 https://reactome.org/PathwayBrowser/#/R-HSA-6785933 UGT8 transfers Gal from UDP-Gal to CERA TAS Homo sapiens 83273 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 83273 R-MMU-1605591 https://reactome.org/PathwayBrowser/#/R-MMU-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Mus musculus 83273 R-MMU-1605797 https://reactome.org/PathwayBrowser/#/R-MMU-1605797 SMPD1 hydrolyzes SPHM IEA Mus musculus 83273 R-MMU-1606273 https://reactome.org/PathwayBrowser/#/R-MMU-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Mus musculus 83273 R-MMU-1606288 https://reactome.org/PathwayBrowser/#/R-MMU-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Mus musculus 83273 R-MMU-1606564 https://reactome.org/PathwayBrowser/#/R-MMU-1606564 GALC hydrolyzes GalCer IEA Mus musculus 83273 R-MMU-1606583 https://reactome.org/PathwayBrowser/#/R-MMU-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Mus musculus 83273 R-MMU-1606602 https://reactome.org/PathwayBrowser/#/R-MMU-1606602 ASAH1 hydrolyzes ceramide IEA Mus musculus 83273 R-MMU-1638845 https://reactome.org/PathwayBrowser/#/R-MMU-1638845 CERK phosphorylates CERA to form C1P IEA Mus musculus 83273 R-MMU-1640164 https://reactome.org/PathwayBrowser/#/R-MMU-1640164 ENPP7 hydrolyzes sphingomyelin IEA Mus musculus 83273 R-MMU-1861788 https://reactome.org/PathwayBrowser/#/R-MMU-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Mus musculus 83273 R-MMU-428205 https://reactome.org/PathwayBrowser/#/R-MMU-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Mus musculus 83273 R-MMU-428231 https://reactome.org/PathwayBrowser/#/R-MMU-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Mus musculus 83273 R-MMU-429786 https://reactome.org/PathwayBrowser/#/R-MMU-429786 SGMS2 transfers phosphocholine onto ceramide IEA Mus musculus 83273 R-MMU-429798 https://reactome.org/PathwayBrowser/#/R-MMU-429798 SGMS1 transfers phosphocholine onto ceramide IEA Mus musculus 83273 R-MMU-5696358 https://reactome.org/PathwayBrowser/#/R-MMU-5696358 TREM,CD300 binds lipids IEA Mus musculus 83273 R-MMU-6785933 https://reactome.org/PathwayBrowser/#/R-MMU-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Mus musculus 83273 R-PFA-1606273 https://reactome.org/PathwayBrowser/#/R-PFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Plasmodium falciparum 83273 R-PFA-429683 https://reactome.org/PathwayBrowser/#/R-PFA-429683 CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus IEA Plasmodium falciparum 83273 R-PFA-429786 https://reactome.org/PathwayBrowser/#/R-PFA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Plasmodium falciparum 83273 R-PFA-429798 https://reactome.org/PathwayBrowser/#/R-PFA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Plasmodium falciparum 83273 R-RNO-1605591 https://reactome.org/PathwayBrowser/#/R-RNO-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Rattus norvegicus 83273 R-RNO-1605797 https://reactome.org/PathwayBrowser/#/R-RNO-1605797 SMPD1 hydrolyzes SPHM IEA Rattus norvegicus 83273 R-RNO-1606273 https://reactome.org/PathwayBrowser/#/R-RNO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Rattus norvegicus 83273 R-RNO-1606288 https://reactome.org/PathwayBrowser/#/R-RNO-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Rattus norvegicus 83273 R-RNO-1606564 https://reactome.org/PathwayBrowser/#/R-RNO-1606564 GALC hydrolyzes GalCer IEA Rattus norvegicus 83273 R-RNO-1606583 https://reactome.org/PathwayBrowser/#/R-RNO-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Rattus norvegicus 83273 R-RNO-1606602 https://reactome.org/PathwayBrowser/#/R-RNO-1606602 ASAH1 hydrolyzes ceramide IEA Rattus norvegicus 83273 R-RNO-1638845 https://reactome.org/PathwayBrowser/#/R-RNO-1638845 CERK phosphorylates CERA to form C1P IEA Rattus norvegicus 83273 R-RNO-1640164 https://reactome.org/PathwayBrowser/#/R-RNO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Rattus norvegicus 83273 R-RNO-1861788 https://reactome.org/PathwayBrowser/#/R-RNO-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Rattus norvegicus 83273 R-RNO-1861789 https://reactome.org/PathwayBrowser/#/R-RNO-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Rattus norvegicus 83273 R-RNO-209562 https://reactome.org/PathwayBrowser/#/R-RNO-209562 Production of ceramide which can activate JNK and other targets TAS Rattus norvegicus 83273 R-RNO-428205 https://reactome.org/PathwayBrowser/#/R-RNO-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Rattus norvegicus 83273 R-RNO-428231 https://reactome.org/PathwayBrowser/#/R-RNO-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Rattus norvegicus 83273 R-RNO-429786 https://reactome.org/PathwayBrowser/#/R-RNO-429786 SGMS2 transfers phosphocholine onto ceramide IEA Rattus norvegicus 83273 R-RNO-429798 https://reactome.org/PathwayBrowser/#/R-RNO-429798 SGMS1 transfers phosphocholine onto ceramide IEA Rattus norvegicus 83273 R-RNO-5696358 https://reactome.org/PathwayBrowser/#/R-RNO-5696358 TREM,CD300 binds lipids IEA Rattus norvegicus 83273 R-RNO-6785933 https://reactome.org/PathwayBrowser/#/R-RNO-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Rattus norvegicus 83273 R-SCE-1606273 https://reactome.org/PathwayBrowser/#/R-SCE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Saccharomyces cerevisiae 83273 R-SCE-1640164 https://reactome.org/PathwayBrowser/#/R-SCE-1640164 ENPP7 hydrolyzes sphingomyelin IEA Saccharomyces cerevisiae 83273 R-SPO-1606273 https://reactome.org/PathwayBrowser/#/R-SPO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Schizosaccharomyces pombe 83273 R-SPO-1640164 https://reactome.org/PathwayBrowser/#/R-SPO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Schizosaccharomyces pombe 83273 R-SSC-1605591 https://reactome.org/PathwayBrowser/#/R-SSC-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Sus scrofa 83273 R-SSC-1605797 https://reactome.org/PathwayBrowser/#/R-SSC-1605797 SMPD1 hydrolyzes SPHM IEA Sus scrofa 83273 R-SSC-1606273 https://reactome.org/PathwayBrowser/#/R-SSC-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Sus scrofa 83273 R-SSC-1606288 https://reactome.org/PathwayBrowser/#/R-SSC-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Sus scrofa 83273 R-SSC-1606564 https://reactome.org/PathwayBrowser/#/R-SSC-1606564 GALC hydrolyzes GalCer IEA Sus scrofa 83273 R-SSC-1606583 https://reactome.org/PathwayBrowser/#/R-SSC-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Sus scrofa 83273 R-SSC-1606602 https://reactome.org/PathwayBrowser/#/R-SSC-1606602 ASAH1 hydrolyzes ceramide IEA Sus scrofa 83273 R-SSC-1638845 https://reactome.org/PathwayBrowser/#/R-SSC-1638845 CERK phosphorylates CERA to form C1P IEA Sus scrofa 83273 R-SSC-1640164 https://reactome.org/PathwayBrowser/#/R-SSC-1640164 ENPP7 hydrolyzes sphingomyelin IEA Sus scrofa 83273 R-SSC-1861788 https://reactome.org/PathwayBrowser/#/R-SSC-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Sus scrofa 83273 R-SSC-1861789 https://reactome.org/PathwayBrowser/#/R-SSC-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Sus scrofa 83273 R-SSC-428205 https://reactome.org/PathwayBrowser/#/R-SSC-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Sus scrofa 83273 R-SSC-428231 https://reactome.org/PathwayBrowser/#/R-SSC-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Sus scrofa 83273 R-SSC-429786 https://reactome.org/PathwayBrowser/#/R-SSC-429786 SGMS2 transfers phosphocholine onto ceramide IEA Sus scrofa 83273 R-SSC-429798 https://reactome.org/PathwayBrowser/#/R-SSC-429798 SGMS1 transfers phosphocholine onto ceramide IEA Sus scrofa 83273 R-SSC-5696358 https://reactome.org/PathwayBrowser/#/R-SSC-5696358 TREM,CD300 binds lipids IEA Sus scrofa 83273 R-SSC-6785933 https://reactome.org/PathwayBrowser/#/R-SSC-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Sus scrofa 83273 R-XTR-1605797 https://reactome.org/PathwayBrowser/#/R-XTR-1605797 SMPD1 hydrolyzes SPHM IEA Xenopus tropicalis 83273 R-XTR-1606273 https://reactome.org/PathwayBrowser/#/R-XTR-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Xenopus tropicalis 83273 R-XTR-1606583 https://reactome.org/PathwayBrowser/#/R-XTR-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Xenopus tropicalis 83273 R-XTR-1638845 https://reactome.org/PathwayBrowser/#/R-XTR-1638845 CERK phosphorylates CERA to form C1P IEA Xenopus tropicalis 83273 R-XTR-1640164 https://reactome.org/PathwayBrowser/#/R-XTR-1640164 ENPP7 hydrolyzes sphingomyelin IEA Xenopus tropicalis 83273 R-XTR-428205 https://reactome.org/PathwayBrowser/#/R-XTR-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Xenopus tropicalis 83273 R-XTR-428231 https://reactome.org/PathwayBrowser/#/R-XTR-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Xenopus tropicalis 83273 R-XTR-429786 https://reactome.org/PathwayBrowser/#/R-XTR-429786 SGMS2 transfers phosphocholine onto ceramide IEA Xenopus tropicalis 83273 R-XTR-429798 https://reactome.org/PathwayBrowser/#/R-XTR-429798 SGMS1 transfers phosphocholine onto ceramide IEA Xenopus tropicalis 83273 R-XTR-5696358 https://reactome.org/PathwayBrowser/#/R-XTR-5696358 TREM,CD300 binds lipids IEA Xenopus tropicalis 8337 R-BTA-1369065 https://reactome.org/PathwayBrowser/#/R-BTA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Bos taurus 8337 R-CEL-1369065 https://reactome.org/PathwayBrowser/#/R-CEL-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Caenorhabditis elegans 8337 R-CFA-1369065 https://reactome.org/PathwayBrowser/#/R-CFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Canis familiaris 8337 R-DME-1369065 https://reactome.org/PathwayBrowser/#/R-DME-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Drosophila melanogaster 8337 R-GGA-1369065 https://reactome.org/PathwayBrowser/#/R-GGA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Gallus gallus 8337 R-HSA-1369065 https://reactome.org/PathwayBrowser/#/R-HSA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix TAS Homo sapiens 8337 R-HSA-5683355 https://reactome.org/PathwayBrowser/#/R-HSA-5683355 Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix TAS Homo sapiens 8337 R-MMU-1369065 https://reactome.org/PathwayBrowser/#/R-MMU-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Mus musculus 8337 R-PFA-1369065 https://reactome.org/PathwayBrowser/#/R-PFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Plasmodium falciparum 8337 R-RNO-1369065 https://reactome.org/PathwayBrowser/#/R-RNO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Rattus norvegicus 8337 R-SPO-1369065 https://reactome.org/PathwayBrowser/#/R-SPO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Schizosaccharomyces pombe 8337 R-SSC-1369065 https://reactome.org/PathwayBrowser/#/R-SSC-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Sus scrofa 8337 R-XTR-1369065 https://reactome.org/PathwayBrowser/#/R-XTR-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Xenopus tropicalis 83400 R-HSA-9697084 https://reactome.org/PathwayBrowser/#/R-HSA-9697084 Defective rpoB in Mtb RNAP transcribes RNA polyanion TAS Homo sapiens 83400 R-HSA-9697085 https://reactome.org/PathwayBrowser/#/R-HSA-9697085 RNAP transcribes Mtb RNA polyanion TAS Homo sapiens 83501 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 83501 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 83501 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 83501 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 83501 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 83501 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 83501 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 83501 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 83501 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 83501 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 8354 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 8354 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 8354 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 8354 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 8354 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 8354 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 8354 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 8354 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 8354 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 8354 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 8354 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 8354 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 8354 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 8354 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 8354 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 8364 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 8364 R-BTA-9617370 https://reactome.org/PathwayBrowser/#/R-BTA-9617370 α1-antagonists bind ADRA1A,B,D IEA Bos taurus 8364 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 8364 R-CEL-9617370 https://reactome.org/PathwayBrowser/#/R-CEL-9617370 α1-antagonists bind ADRA1A,B,D IEA Caenorhabditis elegans 8364 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 8364 R-CFA-9617370 https://reactome.org/PathwayBrowser/#/R-CFA-9617370 α1-antagonists bind ADRA1A,B,D IEA Canis familiaris 8364 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 8364 R-DME-9617370 https://reactome.org/PathwayBrowser/#/R-DME-9617370 α1-antagonists bind ADRA1A,B,D IEA Drosophila melanogaster 8364 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 8364 R-DRE-9617370 https://reactome.org/PathwayBrowser/#/R-DRE-9617370 α1-antagonists bind ADRA1A,B,D IEA Danio rerio 8364 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 8364 R-GGA-9617370 https://reactome.org/PathwayBrowser/#/R-GGA-9617370 α1-antagonists bind ADRA1A,B,D IEA Gallus gallus 8364 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 8364 R-HSA-9617370 https://reactome.org/PathwayBrowser/#/R-HSA-9617370 α1-antagonists bind ADRA1A,B,D TAS Homo sapiens 8364 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 8364 R-MMU-9617370 https://reactome.org/PathwayBrowser/#/R-MMU-9617370 α1-antagonists bind ADRA1A,B,D IEA Mus musculus 8364 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 8364 R-RNO-9617370 https://reactome.org/PathwayBrowser/#/R-RNO-9617370 α1-antagonists bind ADRA1A,B,D IEA Rattus norvegicus 8364 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 8364 R-SSC-9617370 https://reactome.org/PathwayBrowser/#/R-SSC-9617370 α1-antagonists bind ADRA1A,B,D IEA Sus scrofa 8364 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 8364 R-XTR-9617370 https://reactome.org/PathwayBrowser/#/R-XTR-9617370 α1-antagonists bind ADRA1A,B,D IEA Xenopus tropicalis 83690 R-BTA-5691512 https://reactome.org/PathwayBrowser/#/R-BTA-5691512 APEH hydrolyses NAc-Ser-protein IEA Bos taurus 83690 R-CEL-5691512 https://reactome.org/PathwayBrowser/#/R-CEL-5691512 APEH hydrolyses NAc-Ser-protein IEA Caenorhabditis elegans 83690 R-CFA-5691512 https://reactome.org/PathwayBrowser/#/R-CFA-5691512 APEH hydrolyses NAc-Ser-protein IEA Canis familiaris 83690 R-DDI-5691512 https://reactome.org/PathwayBrowser/#/R-DDI-5691512 APEH hydrolyses NAc-Ser-protein IEA Dictyostelium discoideum 83690 R-GGA-5691512 https://reactome.org/PathwayBrowser/#/R-GGA-5691512 APEH hydrolyses NAc-Ser-protein IEA Gallus gallus 83690 R-HSA-141671 https://reactome.org/PathwayBrowser/#/R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex IEA Homo sapiens 83690 R-HSA-5691512 https://reactome.org/PathwayBrowser/#/R-HSA-5691512 APEH hydrolyses NAc-Ser-protein TAS Homo sapiens 83690 R-MMU-5691512 https://reactome.org/PathwayBrowser/#/R-MMU-5691512 APEH hydrolyses NAc-Ser-protein IEA Mus musculus 83690 R-PFA-5691512 https://reactome.org/PathwayBrowser/#/R-PFA-5691512 APEH hydrolyses NAc-Ser-protein IEA Plasmodium falciparum 83690 R-RNO-5691512 https://reactome.org/PathwayBrowser/#/R-RNO-5691512 APEH hydrolyses NAc-Ser-protein IEA Rattus norvegicus 83690 R-SSC-5691512 https://reactome.org/PathwayBrowser/#/R-SSC-5691512 APEH hydrolyses NAc-Ser-protein IEA Sus scrofa 83690 R-XTR-5691512 https://reactome.org/PathwayBrowser/#/R-XTR-5691512 APEH hydrolyses NAc-Ser-protein IEA Xenopus tropicalis 83727 R-BTA-6786720 https://reactome.org/PathwayBrowser/#/R-BTA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Bos taurus 83727 R-CFA-6786720 https://reactome.org/PathwayBrowser/#/R-CFA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Canis familiaris 83727 R-DRE-6786720 https://reactome.org/PathwayBrowser/#/R-DRE-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Danio rerio 83727 R-GGA-6786720 https://reactome.org/PathwayBrowser/#/R-GGA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Gallus gallus 83727 R-HSA-6786720 https://reactome.org/PathwayBrowser/#/R-HSA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA TAS Homo sapiens 83727 R-MMU-6786720 https://reactome.org/PathwayBrowser/#/R-MMU-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Mus musculus 83727 R-RNO-6786720 https://reactome.org/PathwayBrowser/#/R-RNO-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Rattus norvegicus 83727 R-SCE-6786720 https://reactome.org/PathwayBrowser/#/R-SCE-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Saccharomyces cerevisiae 83727 R-SSC-6786720 https://reactome.org/PathwayBrowser/#/R-SSC-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA IEA Sus scrofa 83767 R-BTA-5688289 https://reactome.org/PathwayBrowser/#/R-BTA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Bos taurus 83767 R-BTA-9854463 https://reactome.org/PathwayBrowser/#/R-BTA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Bos taurus 83767 R-CFA-5688289 https://reactome.org/PathwayBrowser/#/R-CFA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Canis familiaris 83767 R-CFA-9854463 https://reactome.org/PathwayBrowser/#/R-CFA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Canis familiaris 83767 R-DDI-5688289 https://reactome.org/PathwayBrowser/#/R-DDI-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Dictyostelium discoideum 83767 R-GGA-5688289 https://reactome.org/PathwayBrowser/#/R-GGA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Gallus gallus 83767 R-GGA-9854463 https://reactome.org/PathwayBrowser/#/R-GGA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Gallus gallus 83767 R-HSA-5688289 https://reactome.org/PathwayBrowser/#/R-HSA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 TAS Homo sapiens 83767 R-HSA-9854463 https://reactome.org/PathwayBrowser/#/R-HSA-9854463 SIRT3 deacetylates AcK-IDH2 dimer TAS Homo sapiens 83767 R-MMU-5688289 https://reactome.org/PathwayBrowser/#/R-MMU-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Mus musculus 83767 R-MMU-9854463 https://reactome.org/PathwayBrowser/#/R-MMU-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Mus musculus 83767 R-RNO-5688289 https://reactome.org/PathwayBrowser/#/R-RNO-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Rattus norvegicus 83767 R-RNO-9854463 https://reactome.org/PathwayBrowser/#/R-RNO-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Rattus norvegicus 83767 R-SCE-5688289 https://reactome.org/PathwayBrowser/#/R-SCE-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Saccharomyces cerevisiae 83767 R-SPO-5688289 https://reactome.org/PathwayBrowser/#/R-SPO-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Schizosaccharomyces pombe 83767 R-SSC-5688289 https://reactome.org/PathwayBrowser/#/R-SSC-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Sus scrofa 83767 R-SSC-9854463 https://reactome.org/PathwayBrowser/#/R-SSC-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Sus scrofa 83782 R-BTA-5602295 https://reactome.org/PathwayBrowser/#/R-BTA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Bos taurus 83782 R-CFA-5602295 https://reactome.org/PathwayBrowser/#/R-CFA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Canis familiaris 83782 R-DRE-5602295 https://reactome.org/PathwayBrowser/#/R-DRE-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Danio rerio 83782 R-HSA-5602295 https://reactome.org/PathwayBrowser/#/R-HSA-5602295 CYP4F22 20-hydroxylates TrXA3 TAS Homo sapiens 83782 R-MMU-5602295 https://reactome.org/PathwayBrowser/#/R-MMU-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Mus musculus 83782 R-SSC-5602295 https://reactome.org/PathwayBrowser/#/R-SSC-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Sus scrofa 83782 R-XTR-5602295 https://reactome.org/PathwayBrowser/#/R-XTR-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Xenopus tropicalis 8391 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 8391 R-BTA-9611721 https://reactome.org/PathwayBrowser/#/R-BTA-9611721 β1-agonists bind ADRB1 IEA Bos taurus 8391 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 8391 R-DME-9611721 https://reactome.org/PathwayBrowser/#/R-DME-9611721 β1-agonists bind ADRB1 IEA Drosophila melanogaster 8391 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 8391 R-DRE-9611721 https://reactome.org/PathwayBrowser/#/R-DRE-9611721 β1-agonists bind ADRB1 IEA Danio rerio 8391 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 8391 R-GGA-9611721 https://reactome.org/PathwayBrowser/#/R-GGA-9611721 β1-agonists bind ADRB1 IEA Gallus gallus 8391 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 8391 R-HSA-9611721 https://reactome.org/PathwayBrowser/#/R-HSA-9611721 β1-agonists bind ADRB1 TAS Homo sapiens 8391 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 8391 R-MMU-9611721 https://reactome.org/PathwayBrowser/#/R-MMU-9611721 β1-agonists bind ADRB1 IEA Mus musculus 8391 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 8391 R-RNO-9611721 https://reactome.org/PathwayBrowser/#/R-RNO-9611721 β1-agonists bind ADRB1 IEA Rattus norvegicus 8391 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 8391 R-SSC-9611721 https://reactome.org/PathwayBrowser/#/R-SSC-9611721 β1-agonists bind ADRB1 IEA Sus scrofa 8391 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 8391 R-XTR-9611721 https://reactome.org/PathwayBrowser/#/R-XTR-9611721 β1-agonists bind ADRB1 IEA Xenopus tropicalis 83955 R-BTA-5693761 https://reactome.org/PathwayBrowser/#/R-BTA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Bos taurus 83955 R-CEL-5693761 https://reactome.org/PathwayBrowser/#/R-CEL-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Caenorhabditis elegans 83955 R-CFA-5693761 https://reactome.org/PathwayBrowser/#/R-CFA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Canis familiaris 83955 R-DDI-5693761 https://reactome.org/PathwayBrowser/#/R-DDI-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Dictyostelium discoideum 83955 R-DME-5693761 https://reactome.org/PathwayBrowser/#/R-DME-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Drosophila melanogaster 83955 R-GGA-5693761 https://reactome.org/PathwayBrowser/#/R-GGA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Gallus gallus 83955 R-HSA-5693761 https://reactome.org/PathwayBrowser/#/R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids TAS Homo sapiens 83955 R-MMU-5693761 https://reactome.org/PathwayBrowser/#/R-MMU-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Mus musculus 83955 R-RNO-5693761 https://reactome.org/PathwayBrowser/#/R-RNO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Rattus norvegicus 83955 R-SCE-5693761 https://reactome.org/PathwayBrowser/#/R-SCE-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Saccharomyces cerevisiae 83955 R-SPO-5693761 https://reactome.org/PathwayBrowser/#/R-SPO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Schizosaccharomyces pombe 83955 R-SSC-5693761 https://reactome.org/PathwayBrowser/#/R-SSC-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Sus scrofa 83955 R-XTR-5693761 https://reactome.org/PathwayBrowser/#/R-XTR-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Xenopus tropicalis 8428 R-BTA-434650 https://reactome.org/PathwayBrowser/#/R-BTA-434650 MATEs mediate extrusion of xenobiotics IEA Bos taurus 8428 R-BTA-549304 https://reactome.org/PathwayBrowser/#/R-BTA-549304 OCT3 mediates renal clearance of organic cations IEA Bos taurus 8428 R-BTA-561072 https://reactome.org/PathwayBrowser/#/R-BTA-561072 OCT3 mediates renal uptake of organic cations IEA Bos taurus 8428 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans 8428 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans 8428 R-CFA-434650 https://reactome.org/PathwayBrowser/#/R-CFA-434650 MATEs mediate extrusion of xenobiotics IEA Canis familiaris 8428 R-CFA-549304 https://reactome.org/PathwayBrowser/#/R-CFA-549304 OCT3 mediates renal clearance of organic cations IEA Canis familiaris 8428 R-CFA-561072 https://reactome.org/PathwayBrowser/#/R-CFA-561072 OCT3 mediates renal uptake of organic cations IEA Canis familiaris 8428 R-DDI-434650 https://reactome.org/PathwayBrowser/#/R-DDI-434650 MATEs mediate extrusion of xenobiotics IEA Dictyostelium discoideum 8428 R-DME-549304 https://reactome.org/PathwayBrowser/#/R-DME-549304 OCT3 mediates renal clearance of organic cations IEA Drosophila melanogaster 8428 R-DME-561072 https://reactome.org/PathwayBrowser/#/R-DME-561072 OCT3 mediates renal uptake of organic cations IEA Drosophila melanogaster 8428 R-DRE-434650 https://reactome.org/PathwayBrowser/#/R-DRE-434650 MATEs mediate extrusion of xenobiotics IEA Danio rerio 8428 R-DRE-549304 https://reactome.org/PathwayBrowser/#/R-DRE-549304 OCT3 mediates renal clearance of organic cations IEA Danio rerio 8428 R-DRE-561072 https://reactome.org/PathwayBrowser/#/R-DRE-561072 OCT3 mediates renal uptake of organic cations IEA Danio rerio 8428 R-GGA-434650 https://reactome.org/PathwayBrowser/#/R-GGA-434650 MATEs mediate extrusion of xenobiotics IEA Gallus gallus 8428 R-GGA-549304 https://reactome.org/PathwayBrowser/#/R-GGA-549304 OCT3 mediates renal clearance of organic cations IEA Gallus gallus 8428 R-GGA-561072 https://reactome.org/PathwayBrowser/#/R-GGA-561072 OCT3 mediates renal uptake of organic cations IEA Gallus gallus 8428 R-HSA-434650 https://reactome.org/PathwayBrowser/#/R-HSA-434650 MATEs mediate extrusion of xenobiotics TAS Homo sapiens 8428 R-HSA-549304 https://reactome.org/PathwayBrowser/#/R-HSA-549304 OCT3 mediates renal clearance of organic cations TAS Homo sapiens 8428 R-HSA-561072 https://reactome.org/PathwayBrowser/#/R-HSA-561072 OCT3 mediates renal uptake of organic cations TAS Homo sapiens 8428 R-MMU-434650 https://reactome.org/PathwayBrowser/#/R-MMU-434650 MATEs mediate extrusion of xenobiotics IEA Mus musculus 8428 R-MMU-549304 https://reactome.org/PathwayBrowser/#/R-MMU-549304 OCT3 mediates renal clearance of organic cations IEA Mus musculus 8428 R-MMU-561072 https://reactome.org/PathwayBrowser/#/R-MMU-561072 OCT3 mediates renal uptake of organic cations IEA Mus musculus 8428 R-PFA-434650 https://reactome.org/PathwayBrowser/#/R-PFA-434650 MATEs mediate extrusion of xenobiotics IEA Plasmodium falciparum 8428 R-RNO-434650 https://reactome.org/PathwayBrowser/#/R-RNO-434650 MATEs mediate extrusion of xenobiotics IEA Rattus norvegicus 8428 R-RNO-549304 https://reactome.org/PathwayBrowser/#/R-RNO-549304 OCT3 mediates renal clearance of organic cations IEA Rattus norvegicus 8428 R-RNO-561072 https://reactome.org/PathwayBrowser/#/R-RNO-561072 OCT3 mediates renal uptake of organic cations IEA Rattus norvegicus 8428 R-SCE-434650 https://reactome.org/PathwayBrowser/#/R-SCE-434650 MATEs mediate extrusion of xenobiotics IEA Saccharomyces cerevisiae 8428 R-SPO-434650 https://reactome.org/PathwayBrowser/#/R-SPO-434650 MATEs mediate extrusion of xenobiotics IEA Schizosaccharomyces pombe 8428 R-SSC-434650 https://reactome.org/PathwayBrowser/#/R-SSC-434650 MATEs mediate extrusion of xenobiotics IEA Sus scrofa 8428 R-SSC-549304 https://reactome.org/PathwayBrowser/#/R-SSC-549304 OCT3 mediates renal clearance of organic cations IEA Sus scrofa 8428 R-SSC-561072 https://reactome.org/PathwayBrowser/#/R-SSC-561072 OCT3 mediates renal uptake of organic cations IEA Sus scrofa 8428 R-XTR-434650 https://reactome.org/PathwayBrowser/#/R-XTR-434650 MATEs mediate extrusion of xenobiotics IEA Xenopus tropicalis 84296 R-HSA-5662904 https://reactome.org/PathwayBrowser/#/R-HSA-5662904 CD isomers transform to BT, BTCA, BZ, ODHBT TAS Homo sapiens 84296 R-HSA-5662908 https://reactome.org/PathwayBrowser/#/R-HSA-5662908 Dopaquinone, cysteine form CD isomers TAS Homo sapiens 84298 R-HSA-5662904 https://reactome.org/PathwayBrowser/#/R-HSA-5662904 CD isomers transform to BT, BTCA, BZ, ODHBT TAS Homo sapiens 84298 R-HSA-5662908 https://reactome.org/PathwayBrowser/#/R-HSA-5662908 Dopaquinone, cysteine form CD isomers TAS Homo sapiens 84301 R-HSA-5662891 https://reactome.org/PathwayBrowser/#/R-HSA-5662891 pheomelanin formation TAS Homo sapiens 84301 R-HSA-5662904 https://reactome.org/PathwayBrowser/#/R-HSA-5662904 CD isomers transform to BT, BTCA, BZ, ODHBT TAS Homo sapiens 84343 R-HSA-5662891 https://reactome.org/PathwayBrowser/#/R-HSA-5662891 pheomelanin formation TAS Homo sapiens 84343 R-HSA-5662904 https://reactome.org/PathwayBrowser/#/R-HSA-5662904 CD isomers transform to BT, BTCA, BZ, ODHBT TAS Homo sapiens 84344 R-HSA-5662891 https://reactome.org/PathwayBrowser/#/R-HSA-5662891 pheomelanin formation TAS Homo sapiens 84344 R-HSA-5662904 https://reactome.org/PathwayBrowser/#/R-HSA-5662904 CD isomers transform to BT, BTCA, BZ, ODHBT TAS Homo sapiens 84373 R-CEL-6786652 https://reactome.org/PathwayBrowser/#/R-CEL-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Caenorhabditis elegans 84373 R-DME-6786652 https://reactome.org/PathwayBrowser/#/R-DME-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Drosophila melanogaster 84373 R-DRE-6786652 https://reactome.org/PathwayBrowser/#/R-DRE-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Danio rerio 84373 R-HSA-6786652 https://reactome.org/PathwayBrowser/#/R-HSA-6786652 CHIT1 hydrolyses CHIT to 3xADGP TAS Homo sapiens 84373 R-MMU-6786652 https://reactome.org/PathwayBrowser/#/R-MMU-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Mus musculus 84373 R-PFA-6786652 https://reactome.org/PathwayBrowser/#/R-PFA-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Plasmodium falciparum 84373 R-RNO-6786652 https://reactome.org/PathwayBrowser/#/R-RNO-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Rattus norvegicus 84373 R-SCE-6786652 https://reactome.org/PathwayBrowser/#/R-SCE-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Saccharomyces cerevisiae 84373 R-SSC-6786652 https://reactome.org/PathwayBrowser/#/R-SSC-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Sus scrofa 84410 R-BTA-1606583 https://reactome.org/PathwayBrowser/#/R-BTA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Bos taurus 84410 R-BTA-1606602 https://reactome.org/PathwayBrowser/#/R-BTA-1606602 ASAH1 hydrolyzes ceramide IEA Bos taurus 84410 R-BTA-428205 https://reactome.org/PathwayBrowser/#/R-BTA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Bos taurus 84410 R-BTA-428231 https://reactome.org/PathwayBrowser/#/R-BTA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Bos taurus 84410 R-BTA-428273 https://reactome.org/PathwayBrowser/#/R-BTA-428273 SPHK1 phosphorylates sphingoid IEA Bos taurus 84410 R-BTA-428664 https://reactome.org/PathwayBrowser/#/R-BTA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Bos taurus 84410 R-BTA-5218845 https://reactome.org/PathwayBrowser/#/R-BTA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Bos taurus 84410 R-BTA-9625814 https://reactome.org/PathwayBrowser/#/R-BTA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Bos taurus 84410 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 84410 R-CEL-1606602 https://reactome.org/PathwayBrowser/#/R-CEL-1606602 ASAH1 hydrolyzes ceramide IEA Caenorhabditis elegans 84410 R-CEL-428205 https://reactome.org/PathwayBrowser/#/R-CEL-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Caenorhabditis elegans 84410 R-CEL-428231 https://reactome.org/PathwayBrowser/#/R-CEL-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Caenorhabditis elegans 84410 R-CEL-428273 https://reactome.org/PathwayBrowser/#/R-CEL-428273 SPHK1 phosphorylates sphingoid IEA Caenorhabditis elegans 84410 R-CEL-9625814 https://reactome.org/PathwayBrowser/#/R-CEL-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Caenorhabditis elegans 84410 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 84410 R-CFA-1606583 https://reactome.org/PathwayBrowser/#/R-CFA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Canis familiaris 84410 R-CFA-1606602 https://reactome.org/PathwayBrowser/#/R-CFA-1606602 ASAH1 hydrolyzes ceramide IEA Canis familiaris 84410 R-CFA-428205 https://reactome.org/PathwayBrowser/#/R-CFA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Canis familiaris 84410 R-CFA-428231 https://reactome.org/PathwayBrowser/#/R-CFA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Canis familiaris 84410 R-CFA-428273 https://reactome.org/PathwayBrowser/#/R-CFA-428273 SPHK1 phosphorylates sphingoid IEA Canis familiaris 84410 R-CFA-428664 https://reactome.org/PathwayBrowser/#/R-CFA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Canis familiaris 84410 R-CFA-5218845 https://reactome.org/PathwayBrowser/#/R-CFA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Canis familiaris 84410 R-CFA-9625814 https://reactome.org/PathwayBrowser/#/R-CFA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Canis familiaris 84410 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 84410 R-DDI-1606583 https://reactome.org/PathwayBrowser/#/R-DDI-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Dictyostelium discoideum 84410 R-DDI-428273 https://reactome.org/PathwayBrowser/#/R-DDI-428273 SPHK1 phosphorylates sphingoid IEA Dictyostelium discoideum 84410 R-DDI-428664 https://reactome.org/PathwayBrowser/#/R-DDI-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Dictyostelium discoideum 84410 R-DDI-9625814 https://reactome.org/PathwayBrowser/#/R-DDI-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Dictyostelium discoideum 84410 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 84410 R-DME-1606583 https://reactome.org/PathwayBrowser/#/R-DME-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Drosophila melanogaster 84410 R-DME-428205 https://reactome.org/PathwayBrowser/#/R-DME-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Drosophila melanogaster 84410 R-DME-428231 https://reactome.org/PathwayBrowser/#/R-DME-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Drosophila melanogaster 84410 R-DME-428273 https://reactome.org/PathwayBrowser/#/R-DME-428273 SPHK1 phosphorylates sphingoid IEA Drosophila melanogaster 84410 R-DME-5218845 https://reactome.org/PathwayBrowser/#/R-DME-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Drosophila melanogaster 84410 R-DME-9625814 https://reactome.org/PathwayBrowser/#/R-DME-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Drosophila melanogaster 84410 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 84410 R-DRE-1606583 https://reactome.org/PathwayBrowser/#/R-DRE-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Danio rerio 84410 R-DRE-428231 https://reactome.org/PathwayBrowser/#/R-DRE-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Danio rerio 84410 R-GGA-1606583 https://reactome.org/PathwayBrowser/#/R-GGA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Gallus gallus 84410 R-GGA-1606602 https://reactome.org/PathwayBrowser/#/R-GGA-1606602 ASAH1 hydrolyzes ceramide IEA Gallus gallus 84410 R-GGA-428205 https://reactome.org/PathwayBrowser/#/R-GGA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Gallus gallus 84410 R-GGA-428231 https://reactome.org/PathwayBrowser/#/R-GGA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Gallus gallus 84410 R-GGA-428273 https://reactome.org/PathwayBrowser/#/R-GGA-428273 SPHK1 phosphorylates sphingoid IEA Gallus gallus 84410 R-GGA-428664 https://reactome.org/PathwayBrowser/#/R-GGA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Gallus gallus 84410 R-GGA-433608 https://reactome.org/PathwayBrowser/#/R-GGA-433608 ceramide + H2O => stearate + sphingosine [endoplasmic reticulum] IEA Gallus gallus 84410 R-GGA-5218845 https://reactome.org/PathwayBrowser/#/R-GGA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Gallus gallus 84410 R-GGA-9625814 https://reactome.org/PathwayBrowser/#/R-GGA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Gallus gallus 84410 R-HSA-1606583 https://reactome.org/PathwayBrowser/#/R-HSA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) TAS Homo sapiens 84410 R-HSA-1606602 https://reactome.org/PathwayBrowser/#/R-HSA-1606602 ASAH1 hydrolyzes ceramide TAS Homo sapiens 84410 R-HSA-428205 https://reactome.org/PathwayBrowser/#/R-HSA-428205 ACER2 hydrolyzes ceramide (Golgi) TAS Homo sapiens 84410 R-HSA-428231 https://reactome.org/PathwayBrowser/#/R-HSA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) TAS Homo sapiens 84410 R-HSA-428273 https://reactome.org/PathwayBrowser/#/R-HSA-428273 SPHK1 phosphorylates sphingoid TAS Homo sapiens 84410 R-HSA-428664 https://reactome.org/PathwayBrowser/#/R-HSA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates TAS Homo sapiens 84410 R-HSA-5218845 https://reactome.org/PathwayBrowser/#/R-HSA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate TAS Homo sapiens 84410 R-HSA-9625814 https://reactome.org/PathwayBrowser/#/R-HSA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation TAS Homo sapiens 84410 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 84410 R-MMU-1606583 https://reactome.org/PathwayBrowser/#/R-MMU-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Mus musculus 84410 R-MMU-1606602 https://reactome.org/PathwayBrowser/#/R-MMU-1606602 ASAH1 hydrolyzes ceramide IEA Mus musculus 84410 R-MMU-428205 https://reactome.org/PathwayBrowser/#/R-MMU-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Mus musculus 84410 R-MMU-428231 https://reactome.org/PathwayBrowser/#/R-MMU-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Mus musculus 84410 R-MMU-428273 https://reactome.org/PathwayBrowser/#/R-MMU-428273 SPHK1 phosphorylates sphingoid IEA Mus musculus 84410 R-MMU-428664 https://reactome.org/PathwayBrowser/#/R-MMU-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Mus musculus 84410 R-MMU-5218845 https://reactome.org/PathwayBrowser/#/R-MMU-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Mus musculus 84410 R-MMU-9625814 https://reactome.org/PathwayBrowser/#/R-MMU-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Mus musculus 84410 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 84410 R-RNO-1606583 https://reactome.org/PathwayBrowser/#/R-RNO-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Rattus norvegicus 84410 R-RNO-1606602 https://reactome.org/PathwayBrowser/#/R-RNO-1606602 ASAH1 hydrolyzes ceramide IEA Rattus norvegicus 84410 R-RNO-428205 https://reactome.org/PathwayBrowser/#/R-RNO-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Rattus norvegicus 84410 R-RNO-428231 https://reactome.org/PathwayBrowser/#/R-RNO-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Rattus norvegicus 84410 R-RNO-428273 https://reactome.org/PathwayBrowser/#/R-RNO-428273 SPHK1 phosphorylates sphingoid IEA Rattus norvegicus 84410 R-RNO-428664 https://reactome.org/PathwayBrowser/#/R-RNO-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Rattus norvegicus 84410 R-RNO-5218845 https://reactome.org/PathwayBrowser/#/R-RNO-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Rattus norvegicus 84410 R-RNO-9625814 https://reactome.org/PathwayBrowser/#/R-RNO-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Rattus norvegicus 84410 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 84410 R-SCE-428273 https://reactome.org/PathwayBrowser/#/R-SCE-428273 SPHK1 phosphorylates sphingoid IEA Saccharomyces cerevisiae 84410 R-SCE-428664 https://reactome.org/PathwayBrowser/#/R-SCE-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Saccharomyces cerevisiae 84410 R-SCE-9625814 https://reactome.org/PathwayBrowser/#/R-SCE-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Saccharomyces cerevisiae 84410 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 84410 R-SPO-428273 https://reactome.org/PathwayBrowser/#/R-SPO-428273 SPHK1 phosphorylates sphingoid IEA Schizosaccharomyces pombe 84410 R-SPO-428664 https://reactome.org/PathwayBrowser/#/R-SPO-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Schizosaccharomyces pombe 84410 R-SPO-9625814 https://reactome.org/PathwayBrowser/#/R-SPO-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Schizosaccharomyces pombe 84410 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 84410 R-SSC-1606583 https://reactome.org/PathwayBrowser/#/R-SSC-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Sus scrofa 84410 R-SSC-1606602 https://reactome.org/PathwayBrowser/#/R-SSC-1606602 ASAH1 hydrolyzes ceramide IEA Sus scrofa 84410 R-SSC-428205 https://reactome.org/PathwayBrowser/#/R-SSC-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Sus scrofa 84410 R-SSC-428231 https://reactome.org/PathwayBrowser/#/R-SSC-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Sus scrofa 84410 R-SSC-428273 https://reactome.org/PathwayBrowser/#/R-SSC-428273 SPHK1 phosphorylates sphingoid IEA Sus scrofa 84410 R-SSC-428664 https://reactome.org/PathwayBrowser/#/R-SSC-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Sus scrofa 84410 R-SSC-5218845 https://reactome.org/PathwayBrowser/#/R-SSC-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Sus scrofa 84410 R-SSC-9625814 https://reactome.org/PathwayBrowser/#/R-SSC-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Sus scrofa 84410 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 84410 R-XTR-1606583 https://reactome.org/PathwayBrowser/#/R-XTR-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Xenopus tropicalis 84410 R-XTR-428205 https://reactome.org/PathwayBrowser/#/R-XTR-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Xenopus tropicalis 84410 R-XTR-428231 https://reactome.org/PathwayBrowser/#/R-XTR-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Xenopus tropicalis 84410 R-XTR-428664 https://reactome.org/PathwayBrowser/#/R-XTR-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Xenopus tropicalis 84410 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 84411 R-BTA-428123 https://reactome.org/PathwayBrowser/#/R-BTA-428123 KDSR reduces 3-ketosphingoid IEA Bos taurus 84411 R-BTA-428127 https://reactome.org/PathwayBrowser/#/R-BTA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Bos taurus 84411 R-CEL-428123 https://reactome.org/PathwayBrowser/#/R-CEL-428123 KDSR reduces 3-ketosphingoid IEA Caenorhabditis elegans 84411 R-CFA-428123 https://reactome.org/PathwayBrowser/#/R-CFA-428123 KDSR reduces 3-ketosphingoid IEA Canis familiaris 84411 R-CFA-428127 https://reactome.org/PathwayBrowser/#/R-CFA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Canis familiaris 84411 R-DDI-428123 https://reactome.org/PathwayBrowser/#/R-DDI-428123 KDSR reduces 3-ketosphingoid IEA Dictyostelium discoideum 84411 R-DME-428123 https://reactome.org/PathwayBrowser/#/R-DME-428123 KDSR reduces 3-ketosphingoid IEA Drosophila melanogaster 84411 R-DME-428127 https://reactome.org/PathwayBrowser/#/R-DME-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Drosophila melanogaster 84411 R-DRE-428127 https://reactome.org/PathwayBrowser/#/R-DRE-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Danio rerio 84411 R-GGA-428127 https://reactome.org/PathwayBrowser/#/R-GGA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Gallus gallus 84411 R-HSA-428123 https://reactome.org/PathwayBrowser/#/R-HSA-428123 KDSR reduces 3-ketosphingoid TAS Homo sapiens 84411 R-HSA-428127 https://reactome.org/PathwayBrowser/#/R-HSA-428127 SPTLC complexes transfer acyl-CoA onto serine TAS Homo sapiens 84411 R-MMU-428123 https://reactome.org/PathwayBrowser/#/R-MMU-428123 KDSR reduces 3-ketosphingoid IEA Mus musculus 84411 R-MMU-428127 https://reactome.org/PathwayBrowser/#/R-MMU-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Mus musculus 84411 R-PFA-428123 https://reactome.org/PathwayBrowser/#/R-PFA-428123 KDSR reduces 3-ketosphingoid IEA Plasmodium falciparum 84411 R-RNO-428123 https://reactome.org/PathwayBrowser/#/R-RNO-428123 KDSR reduces 3-ketosphingoid IEA Rattus norvegicus 84411 R-RNO-428127 https://reactome.org/PathwayBrowser/#/R-RNO-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Rattus norvegicus 84411 R-SCE-428123 https://reactome.org/PathwayBrowser/#/R-SCE-428123 KDSR reduces 3-ketosphingoid IEA Saccharomyces cerevisiae 84411 R-SPO-428123 https://reactome.org/PathwayBrowser/#/R-SPO-428123 KDSR reduces 3-ketosphingoid IEA Schizosaccharomyces pombe 84411 R-SSC-428123 https://reactome.org/PathwayBrowser/#/R-SSC-428123 KDSR reduces 3-ketosphingoid IEA Sus scrofa 84411 R-SSC-428127 https://reactome.org/PathwayBrowser/#/R-SSC-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Sus scrofa 84411 R-XTR-428123 https://reactome.org/PathwayBrowser/#/R-XTR-428123 KDSR reduces 3-ketosphingoid IEA Xenopus tropicalis 84411 R-XTR-428127 https://reactome.org/PathwayBrowser/#/R-XTR-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Xenopus tropicalis 84492 R-SCE-2162292 https://reactome.org/PathwayBrowser/#/R-SCE-2162292 HHB is hydroxylated to DHHB by Coq6 TAS Saccharomyces cerevisiae 84503 R-BTA-2162192 https://reactome.org/PathwayBrowser/#/R-BTA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Bos taurus 84503 R-CEL-2162192 https://reactome.org/PathwayBrowser/#/R-CEL-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Caenorhabditis elegans 84503 R-CFA-2162192 https://reactome.org/PathwayBrowser/#/R-CFA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Canis familiaris 84503 R-DDI-2162192 https://reactome.org/PathwayBrowser/#/R-DDI-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Dictyostelium discoideum 84503 R-DME-2162192 https://reactome.org/PathwayBrowser/#/R-DME-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Drosophila melanogaster 84503 R-DRE-2162192 https://reactome.org/PathwayBrowser/#/R-DRE-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Danio rerio 84503 R-GGA-2162192 https://reactome.org/PathwayBrowser/#/R-GGA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Gallus gallus 84503 R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB IEA Homo sapiens 84503 R-HSA-2162192 https://reactome.org/PathwayBrowser/#/R-HSA-2162192 COQ2 ligates all-E-10PrP2 to PHB TAS Homo sapiens 84503 R-MMU-2162192 https://reactome.org/PathwayBrowser/#/R-MMU-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Mus musculus 84503 R-PFA-2162192 https://reactome.org/PathwayBrowser/#/R-PFA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Plasmodium falciparum 84503 R-RNO-2162192 https://reactome.org/PathwayBrowser/#/R-RNO-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Rattus norvegicus 84503 R-SCE-2162192 https://reactome.org/PathwayBrowser/#/R-SCE-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Saccharomyces cerevisiae 84503 R-SPO-2162192 https://reactome.org/PathwayBrowser/#/R-SPO-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Schizosaccharomyces pombe 84503 R-SSC-2162192 https://reactome.org/PathwayBrowser/#/R-SSC-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Sus scrofa 84503 R-XTR-2162192 https://reactome.org/PathwayBrowser/#/R-XTR-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Xenopus tropicalis 84646 R-BTA-8862152 https://reactome.org/PathwayBrowser/#/R-BTA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Bos taurus 84646 R-CFA-8862152 https://reactome.org/PathwayBrowser/#/R-CFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Canis familiaris 84646 R-DDI-8862152 https://reactome.org/PathwayBrowser/#/R-DDI-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Dictyostelium discoideum 84646 R-DRE-8862152 https://reactome.org/PathwayBrowser/#/R-DRE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Danio rerio 84646 R-HSA-8862152 https://reactome.org/PathwayBrowser/#/R-HSA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP TAS Homo sapiens 84646 R-MMU-8862152 https://reactome.org/PathwayBrowser/#/R-MMU-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Mus musculus 84646 R-PFA-8862152 https://reactome.org/PathwayBrowser/#/R-PFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Plasmodium falciparum 84646 R-RNO-8862152 https://reactome.org/PathwayBrowser/#/R-RNO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Rattus norvegicus 84646 R-SCE-8862152 https://reactome.org/PathwayBrowser/#/R-SCE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Saccharomyces cerevisiae 84646 R-SPO-8862152 https://reactome.org/PathwayBrowser/#/R-SPO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Schizosaccharomyces pombe 84646 R-SSC-8862152 https://reactome.org/PathwayBrowser/#/R-SSC-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Sus scrofa 84646 R-XTR-8862152 https://reactome.org/PathwayBrowser/#/R-XTR-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Xenopus tropicalis 84648 R-BTA-8862152 https://reactome.org/PathwayBrowser/#/R-BTA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Bos taurus 84648 R-CFA-8862152 https://reactome.org/PathwayBrowser/#/R-CFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Canis familiaris 84648 R-DDI-8862152 https://reactome.org/PathwayBrowser/#/R-DDI-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Dictyostelium discoideum 84648 R-DRE-8862152 https://reactome.org/PathwayBrowser/#/R-DRE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Danio rerio 84648 R-HSA-8862152 https://reactome.org/PathwayBrowser/#/R-HSA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP TAS Homo sapiens 84648 R-MMU-8862152 https://reactome.org/PathwayBrowser/#/R-MMU-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Mus musculus 84648 R-PFA-8862152 https://reactome.org/PathwayBrowser/#/R-PFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Plasmodium falciparum 84648 R-RNO-8862152 https://reactome.org/PathwayBrowser/#/R-RNO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Rattus norvegicus 84648 R-SCE-8862152 https://reactome.org/PathwayBrowser/#/R-SCE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Saccharomyces cerevisiae 84648 R-SPO-8862152 https://reactome.org/PathwayBrowser/#/R-SPO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Schizosaccharomyces pombe 84648 R-SSC-8862152 https://reactome.org/PathwayBrowser/#/R-SSC-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Sus scrofa 84648 R-XTR-8862152 https://reactome.org/PathwayBrowser/#/R-XTR-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Xenopus tropicalis 8499 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 8499 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 8499 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 8499 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 8499 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 8499 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 8499 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 8499 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 8499 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 8499 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 8499 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 8499 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 8499 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 8499 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 8499 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 8499 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 8499 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 8499 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 8499 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 8499 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 8499 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 8499 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 8499 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 8499 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 8499 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 8499 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 8499 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 8499 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 8499 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 8499 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 8499 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 8499 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 8499 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 8499 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 8499 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 8499 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 8499 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 8502 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 8502 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 8502 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 8502 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 8502 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 8502 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 8502 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 8502 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 8502 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 8502 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 85164 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 85164 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 85164 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 85164 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 85164 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 85164 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 85164 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 85164 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 85164 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 85164 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 85164 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 85164 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 85164 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 85164 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 85164 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 85164 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 85164 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 85164 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 85164 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 85164 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 85164 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 85164 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 85164 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 85164 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 85262 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 85262 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 85262 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 85262 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 85262 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 85262 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 85262 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 85262 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 85263 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 85263 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 85263 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 85263 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 85263 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 85263 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 85263 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 85263 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 85299 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 85299 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 85299 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 85299 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 85299 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 85299 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 85299 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 85299 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 85505 R-BTA-5689000 https://reactome.org/PathwayBrowser/#/R-BTA-5689000 AADAC deacetylates PHEN IEA Bos taurus 85505 R-CEL-5689000 https://reactome.org/PathwayBrowser/#/R-CEL-5689000 AADAC deacetylates PHEN IEA Caenorhabditis elegans 85505 R-CFA-5689000 https://reactome.org/PathwayBrowser/#/R-CFA-5689000 AADAC deacetylates PHEN IEA Canis familiaris 85505 R-DDI-5689000 https://reactome.org/PathwayBrowser/#/R-DDI-5689000 AADAC deacetylates PHEN IEA Dictyostelium discoideum 85505 R-GGA-5689000 https://reactome.org/PathwayBrowser/#/R-GGA-5689000 AADAC deacetylates PHEN IEA Gallus gallus 85505 R-HSA-5689000 https://reactome.org/PathwayBrowser/#/R-HSA-5689000 AADAC deacetylates PHEN TAS Homo sapiens 85505 R-MMU-5689000 https://reactome.org/PathwayBrowser/#/R-MMU-5689000 AADAC deacetylates PHEN IEA Mus musculus 85505 R-RNO-5689000 https://reactome.org/PathwayBrowser/#/R-RNO-5689000 AADAC deacetylates PHEN IEA Rattus norvegicus 85505 R-SPO-5689000 https://reactome.org/PathwayBrowser/#/R-SPO-5689000 AADAC deacetylates PHEN IEA Schizosaccharomyces pombe 85505 R-SSC-5689000 https://reactome.org/PathwayBrowser/#/R-SSC-5689000 AADAC deacetylates PHEN IEA Sus scrofa 85867 R-BTA-5695964 https://reactome.org/PathwayBrowser/#/R-BTA-5695964 ABHD14B hydrolyses PNPB IEA Bos taurus 85867 R-CEL-5695964 https://reactome.org/PathwayBrowser/#/R-CEL-5695964 ABHD14B hydrolyses PNPB IEA Caenorhabditis elegans 85867 R-CFA-5695964 https://reactome.org/PathwayBrowser/#/R-CFA-5695964 ABHD14B hydrolyses PNPB IEA Canis familiaris 85867 R-DRE-5695964 https://reactome.org/PathwayBrowser/#/R-DRE-5695964 ABHD14B hydrolyses PNPB IEA Danio rerio 85867 R-GGA-5695964 https://reactome.org/PathwayBrowser/#/R-GGA-5695964 ABHD14B hydrolyses PNPB IEA Gallus gallus 85867 R-HSA-5695964 https://reactome.org/PathwayBrowser/#/R-HSA-5695964 ABHD14B hydrolyses PNPB TAS Homo sapiens 85867 R-MMU-5695964 https://reactome.org/PathwayBrowser/#/R-MMU-5695964 ABHD14B hydrolyses PNPB IEA Mus musculus 85867 R-RNO-5695964 https://reactome.org/PathwayBrowser/#/R-RNO-5695964 ABHD14B hydrolyses PNPB IEA Rattus norvegicus 85867 R-SSC-5695964 https://reactome.org/PathwayBrowser/#/R-SSC-5695964 ABHD14B hydrolyses PNPB IEA Sus scrofa 85867 R-XTR-5695964 https://reactome.org/PathwayBrowser/#/R-XTR-5695964 ABHD14B hydrolyses PNPB IEA Xenopus tropicalis 85880 R-BTA-5695989 https://reactome.org/PathwayBrowser/#/R-BTA-5695989 ACAD11 dehydrogenates BH-CoA IEA Bos taurus 85880 R-CFA-5695989 https://reactome.org/PathwayBrowser/#/R-CFA-5695989 ACAD11 dehydrogenates BH-CoA IEA Canis familiaris 85880 R-DRE-5695989 https://reactome.org/PathwayBrowser/#/R-DRE-5695989 ACAD11 dehydrogenates BH-CoA IEA Danio rerio 85880 R-GGA-5695989 https://reactome.org/PathwayBrowser/#/R-GGA-5695989 ACAD11 dehydrogenates BH-CoA IEA Gallus gallus 85880 R-HSA-5695989 https://reactome.org/PathwayBrowser/#/R-HSA-5695989 ACAD11 dehydrogenates BH-CoA TAS Homo sapiens 85880 R-MMU-5695989 https://reactome.org/PathwayBrowser/#/R-MMU-5695989 ACAD11 dehydrogenates BH-CoA IEA Mus musculus 85880 R-RNO-5695989 https://reactome.org/PathwayBrowser/#/R-RNO-5695989 ACAD11 dehydrogenates BH-CoA IEA Rattus norvegicus 85880 R-SSC-5695989 https://reactome.org/PathwayBrowser/#/R-SSC-5695989 ACAD11 dehydrogenates BH-CoA IEA Sus scrofa 85880 R-XTR-5695989 https://reactome.org/PathwayBrowser/#/R-XTR-5695989 ACAD11 dehydrogenates BH-CoA IEA Xenopus tropicalis 85939 R-BTA-6809808 https://reactome.org/PathwayBrowser/#/R-BTA-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Bos taurus 85939 R-CEL-6809808 https://reactome.org/PathwayBrowser/#/R-CEL-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Caenorhabditis elegans 85939 R-CFA-6809808 https://reactome.org/PathwayBrowser/#/R-CFA-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Canis familiaris 85939 R-DME-6809808 https://reactome.org/PathwayBrowser/#/R-DME-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Drosophila melanogaster 85939 R-GGA-6809808 https://reactome.org/PathwayBrowser/#/R-GGA-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Gallus gallus 85939 R-HSA-6809808 https://reactome.org/PathwayBrowser/#/R-HSA-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA TAS Homo sapiens 85939 R-MMU-6809808 https://reactome.org/PathwayBrowser/#/R-MMU-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Mus musculus 85939 R-RNO-6809808 https://reactome.org/PathwayBrowser/#/R-RNO-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Rattus norvegicus 85939 R-SCE-6809808 https://reactome.org/PathwayBrowser/#/R-SCE-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Saccharomyces cerevisiae 85939 R-SSC-6809808 https://reactome.org/PathwayBrowser/#/R-SSC-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Sus scrofa 85939 R-XTR-6809808 https://reactome.org/PathwayBrowser/#/R-XTR-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA IEA Xenopus tropicalis 85944 R-BTA-5695980 https://reactome.org/PathwayBrowser/#/R-BTA-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Bos taurus 85944 R-CEL-5695980 https://reactome.org/PathwayBrowser/#/R-CEL-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Caenorhabditis elegans 85944 R-HSA-5695980 https://reactome.org/PathwayBrowser/#/R-HSA-5695980 ACAD10 dehydrogenates S-2MPDA-CoA TAS Homo sapiens 85944 R-MMU-5695980 https://reactome.org/PathwayBrowser/#/R-MMU-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Mus musculus 85944 R-SSC-5695980 https://reactome.org/PathwayBrowser/#/R-SSC-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Sus scrofa 85945 R-BTA-5695980 https://reactome.org/PathwayBrowser/#/R-BTA-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Bos taurus 85945 R-CEL-5695980 https://reactome.org/PathwayBrowser/#/R-CEL-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Caenorhabditis elegans 85945 R-HSA-5695980 https://reactome.org/PathwayBrowser/#/R-HSA-5695980 ACAD10 dehydrogenates S-2MPDA-CoA TAS Homo sapiens 85945 R-MMU-5695980 https://reactome.org/PathwayBrowser/#/R-MMU-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Mus musculus 85945 R-SSC-5695980 https://reactome.org/PathwayBrowser/#/R-SSC-5695980 ACAD10 dehydrogenates S-2MPDA-CoA IEA Sus scrofa 85973 R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 85973 R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 85973 R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 85973 R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 85973 R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 85973 R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 85973 R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 85973 R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 85973 R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 85973 R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 85973 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 85973 R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 85973 R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 85973 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 85973 R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 85973 R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 85973 R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 85973 R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 85973 R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 85973 R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 85973 R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 85973 R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 85973 R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 85973 R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 85973 R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 85973 R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 85973 R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 85973 R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 85973 R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 85973 R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 85986 R-BTA-6804527 https://reactome.org/PathwayBrowser/#/R-BTA-6804527 INTL1 binds bacterial glycans IEA Bos taurus 85986 R-DRE-6804527 https://reactome.org/PathwayBrowser/#/R-DRE-6804527 INTL1 binds bacterial glycans IEA Danio rerio 85986 R-HSA-6804527 https://reactome.org/PathwayBrowser/#/R-HSA-6804527 INTL1 binds bacterial glycans TAS Homo sapiens 85986 R-MMU-6804527 https://reactome.org/PathwayBrowser/#/R-MMU-6804527 INTL1 binds bacterial glycans IEA Mus musculus 85986 R-RNO-6804527 https://reactome.org/PathwayBrowser/#/R-RNO-6804527 INTL1 binds bacterial glycans IEA Rattus norvegicus 85986 R-SSC-6804527 https://reactome.org/PathwayBrowser/#/R-SSC-6804527 INTL1 binds bacterial glycans IEA Sus scrofa 85986 R-XTR-6804527 https://reactome.org/PathwayBrowser/#/R-XTR-6804527 INTL1 binds bacterial glycans IEA Xenopus tropicalis 85994 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 85994 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 85994 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 85994 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 85994 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 85994 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 85994 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 85994 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 85994 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 85994 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 85994 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 85994 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 85994 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 85994 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 85994 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 85994 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 85994 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 85994 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 85994 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 85994 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 85994 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 85994 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 85994 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 85994 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 85994 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 85994 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 85994 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 85994 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 85994 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 85994 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 85994 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 85994 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 85994 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 85994 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 85994 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 85994 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 85994 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 85994 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 85994 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 85994 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 85994 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 85994 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 85994 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 85994 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 85994 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 85994 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 86019 R-BTA-6788650 https://reactome.org/PathwayBrowser/#/R-BTA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Bos taurus 86019 R-CEL-6788650 https://reactome.org/PathwayBrowser/#/R-CEL-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Caenorhabditis elegans 86019 R-DDI-6788650 https://reactome.org/PathwayBrowser/#/R-DDI-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Dictyostelium discoideum 86019 R-DME-6788650 https://reactome.org/PathwayBrowser/#/R-DME-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Drosophila melanogaster 86019 R-DRE-6788650 https://reactome.org/PathwayBrowser/#/R-DRE-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Danio rerio 86019 R-GGA-6788650 https://reactome.org/PathwayBrowser/#/R-GGA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Gallus gallus 86019 R-HSA-6788650 https://reactome.org/PathwayBrowser/#/R-HSA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins TAS Homo sapiens 86019 R-MMU-6788650 https://reactome.org/PathwayBrowser/#/R-MMU-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Mus musculus 86019 R-PFA-6788650 https://reactome.org/PathwayBrowser/#/R-PFA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Plasmodium falciparum 86019 R-RNO-6788650 https://reactome.org/PathwayBrowser/#/R-RNO-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Rattus norvegicus 86019 R-SCE-6788650 https://reactome.org/PathwayBrowser/#/R-SCE-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Saccharomyces cerevisiae 86019 R-SPO-6788650 https://reactome.org/PathwayBrowser/#/R-SPO-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Schizosaccharomyces pombe 86019 R-XTR-6788650 https://reactome.org/PathwayBrowser/#/R-XTR-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Xenopus tropicalis 86192 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 86192 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 86192 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 86192 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 86192 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 86192 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 86192 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 86192 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 86192 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 86335 R-BTA-6786048 https://reactome.org/PathwayBrowser/#/R-BTA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Bos taurus 86335 R-CFA-6786048 https://reactome.org/PathwayBrowser/#/R-CFA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Canis familiaris 86335 R-DME-6786048 https://reactome.org/PathwayBrowser/#/R-DME-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Drosophila melanogaster 86335 R-DRE-6786048 https://reactome.org/PathwayBrowser/#/R-DRE-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Danio rerio 86335 R-GGA-6786048 https://reactome.org/PathwayBrowser/#/R-GGA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Gallus gallus 86335 R-HSA-6786048 https://reactome.org/PathwayBrowser/#/R-HSA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 TAS Homo sapiens 86335 R-MMU-6786048 https://reactome.org/PathwayBrowser/#/R-MMU-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Mus musculus 86335 R-RNO-6786048 https://reactome.org/PathwayBrowser/#/R-RNO-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Rattus norvegicus 86335 R-SSC-6786048 https://reactome.org/PathwayBrowser/#/R-SSC-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Sus scrofa 86336 R-BTA-6786048 https://reactome.org/PathwayBrowser/#/R-BTA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Bos taurus 86336 R-CFA-6786048 https://reactome.org/PathwayBrowser/#/R-CFA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Canis familiaris 86336 R-DME-6786048 https://reactome.org/PathwayBrowser/#/R-DME-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Drosophila melanogaster 86336 R-DRE-6786048 https://reactome.org/PathwayBrowser/#/R-DRE-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Danio rerio 86336 R-GGA-6786048 https://reactome.org/PathwayBrowser/#/R-GGA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Gallus gallus 86336 R-HSA-6786048 https://reactome.org/PathwayBrowser/#/R-HSA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 TAS Homo sapiens 86336 R-MMU-6786048 https://reactome.org/PathwayBrowser/#/R-MMU-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Mus musculus 86336 R-RNO-6786048 https://reactome.org/PathwayBrowser/#/R-RNO-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Rattus norvegicus 86336 R-SSC-6786048 https://reactome.org/PathwayBrowser/#/R-SSC-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Sus scrofa 86351 R-HSA-6786257 https://reactome.org/PathwayBrowser/#/R-HSA-6786257 DCTPP1 hydrolyses 5idCTP IEA Homo sapiens 86351 R-MMU-6786295 https://reactome.org/PathwayBrowser/#/R-MMU-6786295 Dctpp1 hydrolyses 5idCTP TAS Mus musculus 86361 R-BTA-6786421 https://reactome.org/PathwayBrowser/#/R-BTA-6786421 CHIA hydrolyses chitin IEA Bos taurus 86361 R-CFA-6786421 https://reactome.org/PathwayBrowser/#/R-CFA-6786421 CHIA hydrolyses chitin IEA Canis familiaris 86361 R-DME-6786421 https://reactome.org/PathwayBrowser/#/R-DME-6786421 CHIA hydrolyses chitin IEA Drosophila melanogaster 86361 R-GGA-6786421 https://reactome.org/PathwayBrowser/#/R-GGA-6786421 CHIA hydrolyses chitin IEA Gallus gallus 86361 R-HSA-6786421 https://reactome.org/PathwayBrowser/#/R-HSA-6786421 CHIA hydrolyses chitin TAS Homo sapiens 86361 R-MMU-6786421 https://reactome.org/PathwayBrowser/#/R-MMU-6786421 CHIA hydrolyses chitin IEA Mus musculus 86361 R-PFA-6786421 https://reactome.org/PathwayBrowser/#/R-PFA-6786421 CHIA hydrolyses chitin IEA Plasmodium falciparum 86361 R-RNO-6786421 https://reactome.org/PathwayBrowser/#/R-RNO-6786421 CHIA hydrolyses chitin IEA Rattus norvegicus 86361 R-SCE-6786421 https://reactome.org/PathwayBrowser/#/R-SCE-6786421 CHIA hydrolyses chitin IEA Saccharomyces cerevisiae 86361 R-SSC-6786421 https://reactome.org/PathwayBrowser/#/R-SSC-6786421 CHIA hydrolyses chitin IEA Sus scrofa 86362 R-BTA-6786421 https://reactome.org/PathwayBrowser/#/R-BTA-6786421 CHIA hydrolyses chitin IEA Bos taurus 86362 R-CFA-6786421 https://reactome.org/PathwayBrowser/#/R-CFA-6786421 CHIA hydrolyses chitin IEA Canis familiaris 86362 R-DME-6786421 https://reactome.org/PathwayBrowser/#/R-DME-6786421 CHIA hydrolyses chitin IEA Drosophila melanogaster 86362 R-GGA-6786421 https://reactome.org/PathwayBrowser/#/R-GGA-6786421 CHIA hydrolyses chitin IEA Gallus gallus 86362 R-HSA-6786421 https://reactome.org/PathwayBrowser/#/R-HSA-6786421 CHIA hydrolyses chitin TAS Homo sapiens 86362 R-MMU-6786421 https://reactome.org/PathwayBrowser/#/R-MMU-6786421 CHIA hydrolyses chitin IEA Mus musculus 86362 R-PFA-6786421 https://reactome.org/PathwayBrowser/#/R-PFA-6786421 CHIA hydrolyses chitin IEA Plasmodium falciparum 86362 R-RNO-6786421 https://reactome.org/PathwayBrowser/#/R-RNO-6786421 CHIA hydrolyses chitin IEA Rattus norvegicus 86362 R-SCE-6786421 https://reactome.org/PathwayBrowser/#/R-SCE-6786421 CHIA hydrolyses chitin IEA Saccharomyces cerevisiae 86362 R-SSC-6786421 https://reactome.org/PathwayBrowser/#/R-SSC-6786421 CHIA hydrolyses chitin IEA Sus scrofa 86476 R-BTA-6787623 https://reactome.org/PathwayBrowser/#/R-BTA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Bos taurus 86476 R-BTA-6787642 https://reactome.org/PathwayBrowser/#/R-BTA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Bos taurus 86476 R-CEL-6787623 https://reactome.org/PathwayBrowser/#/R-CEL-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Caenorhabditis elegans 86476 R-CEL-6787642 https://reactome.org/PathwayBrowser/#/R-CEL-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Caenorhabditis elegans 86476 R-CFA-6787623 https://reactome.org/PathwayBrowser/#/R-CFA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Canis familiaris 86476 R-CFA-6787642 https://reactome.org/PathwayBrowser/#/R-CFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Canis familiaris 86476 R-DDI-6787623 https://reactome.org/PathwayBrowser/#/R-DDI-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Dictyostelium discoideum 86476 R-DDI-6787642 https://reactome.org/PathwayBrowser/#/R-DDI-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Dictyostelium discoideum 86476 R-DME-6787623 https://reactome.org/PathwayBrowser/#/R-DME-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Drosophila melanogaster 86476 R-DME-6787642 https://reactome.org/PathwayBrowser/#/R-DME-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Drosophila melanogaster 86476 R-DRE-6787623 https://reactome.org/PathwayBrowser/#/R-DRE-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Danio rerio 86476 R-DRE-6787642 https://reactome.org/PathwayBrowser/#/R-DRE-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Danio rerio 86476 R-GGA-6787623 https://reactome.org/PathwayBrowser/#/R-GGA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Gallus gallus 86476 R-GGA-6787642 https://reactome.org/PathwayBrowser/#/R-GGA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Gallus gallus 86476 R-HSA-6787623 https://reactome.org/PathwayBrowser/#/R-HSA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal TAS Homo sapiens 86476 R-HSA-6787642 https://reactome.org/PathwayBrowser/#/R-HSA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc TAS Homo sapiens 86476 R-MMU-6787623 https://reactome.org/PathwayBrowser/#/R-MMU-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Mus musculus 86476 R-MMU-6787642 https://reactome.org/PathwayBrowser/#/R-MMU-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Mus musculus 86476 R-PFA-6787623 https://reactome.org/PathwayBrowser/#/R-PFA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Plasmodium falciparum 86476 R-PFA-6787642 https://reactome.org/PathwayBrowser/#/R-PFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Plasmodium falciparum 86476 R-RNO-6787623 https://reactome.org/PathwayBrowser/#/R-RNO-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Rattus norvegicus 86476 R-RNO-6787642 https://reactome.org/PathwayBrowser/#/R-RNO-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Rattus norvegicus 86476 R-SSC-6787623 https://reactome.org/PathwayBrowser/#/R-SSC-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Sus scrofa 86476 R-SSC-6787642 https://reactome.org/PathwayBrowser/#/R-SSC-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Sus scrofa 86476 R-XTR-6787623 https://reactome.org/PathwayBrowser/#/R-XTR-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Xenopus tropicalis 86476 R-XTR-6787642 https://reactome.org/PathwayBrowser/#/R-XTR-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Xenopus tropicalis 8665 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 8665 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 8665 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 8665 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 8665 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 8665 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 8665 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 8665 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 8665 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 8665 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 8665 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 8665 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 8665 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 8665 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 8665 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 8692 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 8692 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 8692 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 8692 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 8692 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 8692 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 8692 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 8692 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 8692 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 8692 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 8692 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 8692 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 8692 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 8692 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 8692 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 8692 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 8692 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 8692 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 8692 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 8692 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 8692 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 8692 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 8692 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 8692 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 8692 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 8692 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 8692 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 8692 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 8692 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 8692 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 8692 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 8692 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 8692 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 8692 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 8692 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 8692 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 8692 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 8692 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 8692 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 8692 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 8692 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 8692 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 86988 R-BTA-6787811 https://reactome.org/PathwayBrowser/#/R-BTA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Bos taurus 86988 R-CEL-6787811 https://reactome.org/PathwayBrowser/#/R-CEL-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Caenorhabditis elegans 86988 R-CFA-6787811 https://reactome.org/PathwayBrowser/#/R-CFA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Canis familiaris 86988 R-DDI-6787811 https://reactome.org/PathwayBrowser/#/R-DDI-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Dictyostelium discoideum 86988 R-DME-6787811 https://reactome.org/PathwayBrowser/#/R-DME-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Drosophila melanogaster 86988 R-GGA-6787811 https://reactome.org/PathwayBrowser/#/R-GGA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Gallus gallus 86988 R-HSA-6787811 https://reactome.org/PathwayBrowser/#/R-HSA-6787811 HAO2 tetramer oxidises 2OH-PALM TAS Homo sapiens 86988 R-MMU-6787811 https://reactome.org/PathwayBrowser/#/R-MMU-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Mus musculus 86988 R-RNO-6787811 https://reactome.org/PathwayBrowser/#/R-RNO-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Rattus norvegicus 86988 R-SSC-6787811 https://reactome.org/PathwayBrowser/#/R-SSC-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Sus scrofa 86988 R-XTR-6787811 https://reactome.org/PathwayBrowser/#/R-XTR-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Xenopus tropicalis 8707 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 8707 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 8707 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 8707 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 8707 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 8707 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 8707 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 8707 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 8707 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 8707 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 8707 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 8707 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 8707 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 8707 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 8707 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 8707 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 8707 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 8707 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 8707 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 8707 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 8707 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 8707 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 8707 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 8707 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 8707 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 8707 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 8707 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 8707 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 8713 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 8713 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 8713 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 8713 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 8713 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 8713 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 8713 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 8713 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 8713 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 8713 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 8713 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 8713 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 87167 R-BTA-6788650 https://reactome.org/PathwayBrowser/#/R-BTA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Bos taurus 87167 R-CEL-6788650 https://reactome.org/PathwayBrowser/#/R-CEL-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Caenorhabditis elegans 87167 R-DDI-6788650 https://reactome.org/PathwayBrowser/#/R-DDI-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Dictyostelium discoideum 87167 R-DME-6788650 https://reactome.org/PathwayBrowser/#/R-DME-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Drosophila melanogaster 87167 R-DRE-6788650 https://reactome.org/PathwayBrowser/#/R-DRE-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Danio rerio 87167 R-GGA-6788650 https://reactome.org/PathwayBrowser/#/R-GGA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Gallus gallus 87167 R-HSA-6788650 https://reactome.org/PathwayBrowser/#/R-HSA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins TAS Homo sapiens 87167 R-MMU-6788650 https://reactome.org/PathwayBrowser/#/R-MMU-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Mus musculus 87167 R-PFA-6788650 https://reactome.org/PathwayBrowser/#/R-PFA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Plasmodium falciparum 87167 R-RNO-6788650 https://reactome.org/PathwayBrowser/#/R-RNO-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Rattus norvegicus 87167 R-SCE-6788650 https://reactome.org/PathwayBrowser/#/R-SCE-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Saccharomyces cerevisiae 87167 R-SPO-6788650 https://reactome.org/PathwayBrowser/#/R-SPO-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Schizosaccharomyces pombe 87167 R-XTR-6788650 https://reactome.org/PathwayBrowser/#/R-XTR-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins IEA Xenopus tropicalis 87170 R-HSA-6782264 https://reactome.org/PathwayBrowser/#/R-HSA-6782264 CTU1:CTU2:URM1 thiolates uridine-34 in tRNAs TAS Homo sapiens 87171 R-HSA-6787447 https://reactome.org/PathwayBrowser/#/R-HSA-6787447 TRMU (MTO2, MTU1) transfers a sulfur atom to 5-taurinomethyluridine-34 in tRNA IEA Homo sapiens 87172 R-HSA-6787403 https://reactome.org/PathwayBrowser/#/R-HSA-6787403 GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA IEA Homo sapiens 87172 R-HSA-6787447 https://reactome.org/PathwayBrowser/#/R-HSA-6787447 TRMU (MTO2, MTU1) transfers a sulfur atom to 5-taurinomethyluridine-34 in tRNA IEA Homo sapiens 87176 R-BTA-6788855 https://reactome.org/PathwayBrowser/#/R-BTA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Bos taurus 87176 R-CEL-6788855 https://reactome.org/PathwayBrowser/#/R-CEL-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Caenorhabditis elegans 87176 R-CEL-6788867 https://reactome.org/PathwayBrowser/#/R-CEL-6788867 FN3K phosphorylates ketosamines IEA Caenorhabditis elegans 87176 R-CFA-6788855 https://reactome.org/PathwayBrowser/#/R-CFA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Canis familiaris 87176 R-CFA-6788867 https://reactome.org/PathwayBrowser/#/R-CFA-6788867 FN3K phosphorylates ketosamines IEA Canis familiaris 87176 R-DRE-6788855 https://reactome.org/PathwayBrowser/#/R-DRE-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Danio rerio 87176 R-DRE-6788867 https://reactome.org/PathwayBrowser/#/R-DRE-6788867 FN3K phosphorylates ketosamines IEA Danio rerio 87176 R-GGA-6788855 https://reactome.org/PathwayBrowser/#/R-GGA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Gallus gallus 87176 R-GGA-6788867 https://reactome.org/PathwayBrowser/#/R-GGA-6788867 FN3K phosphorylates ketosamines IEA Gallus gallus 87176 R-HSA-6788855 https://reactome.org/PathwayBrowser/#/R-HSA-6788855 FN3KRP phosphorylates PsiAm, RibAm TAS Homo sapiens 87176 R-HSA-6788867 https://reactome.org/PathwayBrowser/#/R-HSA-6788867 FN3K phosphorylates ketosamines TAS Homo sapiens 87176 R-MMU-6788855 https://reactome.org/PathwayBrowser/#/R-MMU-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Mus musculus 87176 R-MMU-6788867 https://reactome.org/PathwayBrowser/#/R-MMU-6788867 FN3K phosphorylates ketosamines IEA Mus musculus 87176 R-RNO-6788855 https://reactome.org/PathwayBrowser/#/R-RNO-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Rattus norvegicus 87176 R-RNO-6788867 https://reactome.org/PathwayBrowser/#/R-RNO-6788867 FN3K phosphorylates ketosamines IEA Rattus norvegicus 87176 R-SSC-6788855 https://reactome.org/PathwayBrowser/#/R-SSC-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Sus scrofa 87176 R-SSC-6788867 https://reactome.org/PathwayBrowser/#/R-SSC-6788867 FN3K phosphorylates ketosamines IEA Sus scrofa 87176 R-XTR-6788855 https://reactome.org/PathwayBrowser/#/R-XTR-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Xenopus tropicalis 87176 R-XTR-6788867 https://reactome.org/PathwayBrowser/#/R-XTR-6788867 FN3K phosphorylates ketosamines IEA Xenopus tropicalis 87177 R-BTA-6788855 https://reactome.org/PathwayBrowser/#/R-BTA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Bos taurus 87177 R-CEL-6788855 https://reactome.org/PathwayBrowser/#/R-CEL-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Caenorhabditis elegans 87177 R-CEL-6788867 https://reactome.org/PathwayBrowser/#/R-CEL-6788867 FN3K phosphorylates ketosamines IEA Caenorhabditis elegans 87177 R-CFA-6788855 https://reactome.org/PathwayBrowser/#/R-CFA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Canis familiaris 87177 R-CFA-6788867 https://reactome.org/PathwayBrowser/#/R-CFA-6788867 FN3K phosphorylates ketosamines IEA Canis familiaris 87177 R-DRE-6788855 https://reactome.org/PathwayBrowser/#/R-DRE-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Danio rerio 87177 R-DRE-6788867 https://reactome.org/PathwayBrowser/#/R-DRE-6788867 FN3K phosphorylates ketosamines IEA Danio rerio 87177 R-GGA-6788855 https://reactome.org/PathwayBrowser/#/R-GGA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Gallus gallus 87177 R-GGA-6788867 https://reactome.org/PathwayBrowser/#/R-GGA-6788867 FN3K phosphorylates ketosamines IEA Gallus gallus 87177 R-HSA-6788855 https://reactome.org/PathwayBrowser/#/R-HSA-6788855 FN3KRP phosphorylates PsiAm, RibAm TAS Homo sapiens 87177 R-HSA-6788867 https://reactome.org/PathwayBrowser/#/R-HSA-6788867 FN3K phosphorylates ketosamines TAS Homo sapiens 87177 R-MMU-6788855 https://reactome.org/PathwayBrowser/#/R-MMU-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Mus musculus 87177 R-MMU-6788867 https://reactome.org/PathwayBrowser/#/R-MMU-6788867 FN3K phosphorylates ketosamines IEA Mus musculus 87177 R-RNO-6788855 https://reactome.org/PathwayBrowser/#/R-RNO-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Rattus norvegicus 87177 R-RNO-6788867 https://reactome.org/PathwayBrowser/#/R-RNO-6788867 FN3K phosphorylates ketosamines IEA Rattus norvegicus 87177 R-SSC-6788855 https://reactome.org/PathwayBrowser/#/R-SSC-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Sus scrofa 87177 R-SSC-6788867 https://reactome.org/PathwayBrowser/#/R-SSC-6788867 FN3K phosphorylates ketosamines IEA Sus scrofa 87177 R-XTR-6788855 https://reactome.org/PathwayBrowser/#/R-XTR-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Xenopus tropicalis 87177 R-XTR-6788867 https://reactome.org/PathwayBrowser/#/R-XTR-6788867 FN3K phosphorylates ketosamines IEA Xenopus tropicalis 87178 R-CEL-6788867 https://reactome.org/PathwayBrowser/#/R-CEL-6788867 FN3K phosphorylates ketosamines IEA Caenorhabditis elegans 87178 R-CFA-6788867 https://reactome.org/PathwayBrowser/#/R-CFA-6788867 FN3K phosphorylates ketosamines IEA Canis familiaris 87178 R-DRE-6788867 https://reactome.org/PathwayBrowser/#/R-DRE-6788867 FN3K phosphorylates ketosamines IEA Danio rerio 87178 R-GGA-6788867 https://reactome.org/PathwayBrowser/#/R-GGA-6788867 FN3K phosphorylates ketosamines IEA Gallus gallus 87178 R-HSA-6788867 https://reactome.org/PathwayBrowser/#/R-HSA-6788867 FN3K phosphorylates ketosamines TAS Homo sapiens 87178 R-MMU-6788867 https://reactome.org/PathwayBrowser/#/R-MMU-6788867 FN3K phosphorylates ketosamines IEA Mus musculus 87178 R-RNO-6788867 https://reactome.org/PathwayBrowser/#/R-RNO-6788867 FN3K phosphorylates ketosamines IEA Rattus norvegicus 87178 R-SSC-6788867 https://reactome.org/PathwayBrowser/#/R-SSC-6788867 FN3K phosphorylates ketosamines IEA Sus scrofa 87178 R-XTR-6788867 https://reactome.org/PathwayBrowser/#/R-XTR-6788867 FN3K phosphorylates ketosamines IEA Xenopus tropicalis 87179 R-BTA-6788855 https://reactome.org/PathwayBrowser/#/R-BTA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Bos taurus 87179 R-CEL-6788855 https://reactome.org/PathwayBrowser/#/R-CEL-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Caenorhabditis elegans 87179 R-CEL-6788867 https://reactome.org/PathwayBrowser/#/R-CEL-6788867 FN3K phosphorylates ketosamines IEA Caenorhabditis elegans 87179 R-CFA-6788855 https://reactome.org/PathwayBrowser/#/R-CFA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Canis familiaris 87179 R-CFA-6788867 https://reactome.org/PathwayBrowser/#/R-CFA-6788867 FN3K phosphorylates ketosamines IEA Canis familiaris 87179 R-DRE-6788855 https://reactome.org/PathwayBrowser/#/R-DRE-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Danio rerio 87179 R-DRE-6788867 https://reactome.org/PathwayBrowser/#/R-DRE-6788867 FN3K phosphorylates ketosamines IEA Danio rerio 87179 R-GGA-6788855 https://reactome.org/PathwayBrowser/#/R-GGA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Gallus gallus 87179 R-GGA-6788867 https://reactome.org/PathwayBrowser/#/R-GGA-6788867 FN3K phosphorylates ketosamines IEA Gallus gallus 87179 R-HSA-6788855 https://reactome.org/PathwayBrowser/#/R-HSA-6788855 FN3KRP phosphorylates PsiAm, RibAm TAS Homo sapiens 87179 R-HSA-6788867 https://reactome.org/PathwayBrowser/#/R-HSA-6788867 FN3K phosphorylates ketosamines TAS Homo sapiens 87179 R-MMU-6788855 https://reactome.org/PathwayBrowser/#/R-MMU-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Mus musculus 87179 R-MMU-6788867 https://reactome.org/PathwayBrowser/#/R-MMU-6788867 FN3K phosphorylates ketosamines IEA Mus musculus 87179 R-RNO-6788855 https://reactome.org/PathwayBrowser/#/R-RNO-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Rattus norvegicus 87179 R-RNO-6788867 https://reactome.org/PathwayBrowser/#/R-RNO-6788867 FN3K phosphorylates ketosamines IEA Rattus norvegicus 87179 R-SSC-6788855 https://reactome.org/PathwayBrowser/#/R-SSC-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Sus scrofa 87179 R-SSC-6788867 https://reactome.org/PathwayBrowser/#/R-SSC-6788867 FN3K phosphorylates ketosamines IEA Sus scrofa 87179 R-XTR-6788855 https://reactome.org/PathwayBrowser/#/R-XTR-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Xenopus tropicalis 87179 R-XTR-6788867 https://reactome.org/PathwayBrowser/#/R-XTR-6788867 FN3K phosphorylates ketosamines IEA Xenopus tropicalis 87180 R-BTA-6788855 https://reactome.org/PathwayBrowser/#/R-BTA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Bos taurus 87180 R-CEL-6788855 https://reactome.org/PathwayBrowser/#/R-CEL-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Caenorhabditis elegans 87180 R-CEL-6788867 https://reactome.org/PathwayBrowser/#/R-CEL-6788867 FN3K phosphorylates ketosamines IEA Caenorhabditis elegans 87180 R-CFA-6788855 https://reactome.org/PathwayBrowser/#/R-CFA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Canis familiaris 87180 R-CFA-6788867 https://reactome.org/PathwayBrowser/#/R-CFA-6788867 FN3K phosphorylates ketosamines IEA Canis familiaris 87180 R-DRE-6788855 https://reactome.org/PathwayBrowser/#/R-DRE-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Danio rerio 87180 R-DRE-6788867 https://reactome.org/PathwayBrowser/#/R-DRE-6788867 FN3K phosphorylates ketosamines IEA Danio rerio 87180 R-GGA-6788855 https://reactome.org/PathwayBrowser/#/R-GGA-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Gallus gallus 87180 R-GGA-6788867 https://reactome.org/PathwayBrowser/#/R-GGA-6788867 FN3K phosphorylates ketosamines IEA Gallus gallus 87180 R-HSA-6788855 https://reactome.org/PathwayBrowser/#/R-HSA-6788855 FN3KRP phosphorylates PsiAm, RibAm TAS Homo sapiens 87180 R-HSA-6788867 https://reactome.org/PathwayBrowser/#/R-HSA-6788867 FN3K phosphorylates ketosamines TAS Homo sapiens 87180 R-MMU-6788855 https://reactome.org/PathwayBrowser/#/R-MMU-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Mus musculus 87180 R-MMU-6788867 https://reactome.org/PathwayBrowser/#/R-MMU-6788867 FN3K phosphorylates ketosamines IEA Mus musculus 87180 R-RNO-6788855 https://reactome.org/PathwayBrowser/#/R-RNO-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Rattus norvegicus 87180 R-RNO-6788867 https://reactome.org/PathwayBrowser/#/R-RNO-6788867 FN3K phosphorylates ketosamines IEA Rattus norvegicus 87180 R-SSC-6788855 https://reactome.org/PathwayBrowser/#/R-SSC-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Sus scrofa 87180 R-SSC-6788867 https://reactome.org/PathwayBrowser/#/R-SSC-6788867 FN3K phosphorylates ketosamines IEA Sus scrofa 87180 R-XTR-6788855 https://reactome.org/PathwayBrowser/#/R-XTR-6788855 FN3KRP phosphorylates PsiAm, RibAm IEA Xenopus tropicalis 87180 R-XTR-6788867 https://reactome.org/PathwayBrowser/#/R-XTR-6788867 FN3K phosphorylates ketosamines IEA Xenopus tropicalis 87362 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 87362 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 87362 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 87362 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 87362 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 87362 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 87362 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 87362 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 87362 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 8756 R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 8756 R-HSA-9681314 https://reactome.org/PathwayBrowser/#/R-HSA-9681314 Replication transcription complex binds SARS-CoV-1 genomic RNA TAS Homo sapiens 8756 R-HSA-9681651 https://reactome.org/PathwayBrowser/#/R-HSA-9681651 nsp8 generates RNA primers TAS Homo sapiens 8756 R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 8756 R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 8756 R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 8756 R-HSA-9682603 https://reactome.org/PathwayBrowser/#/R-HSA-9682603 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 8756 R-HSA-9682695 https://reactome.org/PathwayBrowser/#/R-HSA-9682695 nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template TAS Homo sapiens 8756 R-HSA-9683618 https://reactome.org/PathwayBrowser/#/R-HSA-9683618 mRNA3 is translated to protein 3a TAS Homo sapiens 8756 R-HSA-9683622 https://reactome.org/PathwayBrowser/#/R-HSA-9683622 mRNA5 is translated to protein M TAS Homo sapiens 8756 R-HSA-9683624 https://reactome.org/PathwayBrowser/#/R-HSA-9683624 mRNA2 is translated to Spike TAS Homo sapiens 8756 R-HSA-9683656 https://reactome.org/PathwayBrowser/#/R-HSA-9683656 mRNA4 is translated to protein E TAS Homo sapiens 8756 R-HSA-9683735 https://reactome.org/PathwayBrowser/#/R-HSA-9683735 mRNA9 is translated to Nucleoprotein TAS Homo sapiens 8756 R-HSA-9684229 https://reactome.org/PathwayBrowser/#/R-HSA-9684229 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 8756 R-HSA-9684234 https://reactome.org/PathwayBrowser/#/R-HSA-9684234 Encapsidation of SARS coronavirus genomic RNA TAS Homo sapiens 8756 R-HSA-9684238 https://reactome.org/PathwayBrowser/#/R-HSA-9684238 E and N are recruited to the M lattice TAS Homo sapiens 8756 R-HSA-9684241 https://reactome.org/PathwayBrowser/#/R-HSA-9684241 Recruitment of Spike trimer to assembling virion TAS Homo sapiens 8756 R-HSA-9684277 https://reactome.org/PathwayBrowser/#/R-HSA-9684277 mRNA1 is translated to pp1ab TAS Homo sapiens 8756 R-HSA-9684301 https://reactome.org/PathwayBrowser/#/R-HSA-9684301 mRNA1 is translated to pp1a TAS Homo sapiens 8756 R-HSA-9685519 https://reactome.org/PathwayBrowser/#/R-HSA-9685519 Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) TAS Homo sapiens 8756 R-HSA-9685531 https://reactome.org/PathwayBrowser/#/R-HSA-9685531 SARS virus buds into ERGIC lumen TAS Homo sapiens 8756 R-HSA-9685639 https://reactome.org/PathwayBrowser/#/R-HSA-9685639 Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching TAS Homo sapiens 8756 R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 8756 R-HSA-9686174 https://reactome.org/PathwayBrowser/#/R-HSA-9686174 Accessory proteins are recruited to the maturing virion TAS Homo sapiens 8756 R-HSA-9687388 https://reactome.org/PathwayBrowser/#/R-HSA-9687388 SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 8756 R-HSA-9693589 https://reactome.org/PathwayBrowser/#/R-HSA-9693589 SARS-CoV-1 dsRNA intermediates bind DDX58 TAS Homo sapiens 8756 R-HSA-9693590 https://reactome.org/PathwayBrowser/#/R-HSA-9693590 SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC IEA Homo sapiens 8756 R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 8756 R-HSA-9694274 https://reactome.org/PathwayBrowser/#/R-HSA-9694274 mRNA1 is translated to pp1ab IEA Homo sapiens 8756 R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 8756 R-HSA-9694280 https://reactome.org/PathwayBrowser/#/R-HSA-9694280 mRNA4 is translated to protein E TAS Homo sapiens 8756 R-HSA-9694281 https://reactome.org/PathwayBrowser/#/R-HSA-9694281 Encapsidation of SARS coronavirus genomic RNA IEA Homo sapiens 8756 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 8756 R-HSA-9694334 https://reactome.org/PathwayBrowser/#/R-HSA-9694334 mRNA1 is translated to pp1a IEA Homo sapiens 8756 R-HSA-9694344 https://reactome.org/PathwayBrowser/#/R-HSA-9694344 Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching IEA Homo sapiens 8756 R-HSA-9694370 https://reactome.org/PathwayBrowser/#/R-HSA-9694370 mRNA9a is translated to Nucleoprotein TAS Homo sapiens 8756 R-HSA-9694444 https://reactome.org/PathwayBrowser/#/R-HSA-9694444 E and N are recruited to the M lattice IEA Homo sapiens 8756 R-HSA-9694447 https://reactome.org/PathwayBrowser/#/R-HSA-9694447 mRNA2 is translated to Spike TAS Homo sapiens 8756 R-HSA-9694454 https://reactome.org/PathwayBrowser/#/R-HSA-9694454 Replication transcription complex binds SARS-CoV-2 genomic RNA TAS Homo sapiens 8756 R-HSA-9694455 https://reactome.org/PathwayBrowser/#/R-HSA-9694455 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 8756 R-HSA-9694471 https://reactome.org/PathwayBrowser/#/R-HSA-9694471 Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) TAS Homo sapiens 8756 R-HSA-9694528 https://reactome.org/PathwayBrowser/#/R-HSA-9694528 Accessory proteins are recruited to the maturing virion IEA Homo sapiens 8756 R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 8756 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 8756 R-HSA-9694553 https://reactome.org/PathwayBrowser/#/R-HSA-9694553 Recruitment of Spike trimer to assembling virion IEA Homo sapiens 8756 R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 8756 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 8756 R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 8756 R-HSA-9694633 https://reactome.org/PathwayBrowser/#/R-HSA-9694633 SARS virus buds into ERGIC lumen IEA Homo sapiens 8756 R-HSA-9694641 https://reactome.org/PathwayBrowser/#/R-HSA-9694641 Viral release IEA Homo sapiens 8756 R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 8756 R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 8756 R-HSA-9694677 https://reactome.org/PathwayBrowser/#/R-HSA-9694677 ZCRB1 binds 5'UTR of SARS-CoV-2 genomic RNA IEA Homo sapiens 8756 R-HSA-9694681 https://reactome.org/PathwayBrowser/#/R-HSA-9694681 mRNA5 is translated to protein M TAS Homo sapiens 8756 R-HSA-9694689 https://reactome.org/PathwayBrowser/#/R-HSA-9694689 Fusion and Release of SARS-CoV-2 Nucleocapsid IEA Homo sapiens 8756 R-HSA-9694723 https://reactome.org/PathwayBrowser/#/R-HSA-9694723 Uncoating of SARS-CoV-2 Genome IEA Homo sapiens 8756 R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 8756 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 8756 R-HSA-9694794 https://reactome.org/PathwayBrowser/#/R-HSA-9694794 mRNA3 is translated to protein 3a TAS Homo sapiens 8756 R-HSA-9697423 https://reactome.org/PathwayBrowser/#/R-HSA-9697423 Endocytosis of SARS-CoV-2 Virion IEA Homo sapiens 8756 R-HSA-9698988 https://reactome.org/PathwayBrowser/#/R-HSA-9698988 Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid TAS Homo sapiens 8756 R-HSA-9699007 https://reactome.org/PathwayBrowser/#/R-HSA-9699007 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 8756 R-HSA-9705961 https://reactome.org/PathwayBrowser/#/R-HSA-9705961 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 8756 R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 8756 R-HSA-9727292 https://reactome.org/PathwayBrowser/#/R-HSA-9727292 mRNA6 is translated to protein 6 TAS Homo sapiens 8756 R-HSA-9727297 https://reactome.org/PathwayBrowser/#/R-HSA-9727297 mRNA7 is translated to protein 7a TAS Homo sapiens 8756 R-HSA-9727303 https://reactome.org/PathwayBrowser/#/R-HSA-9727303 mRNA9 is translated to protein 9b TAS Homo sapiens 8756 R-HSA-9727305 https://reactome.org/PathwayBrowser/#/R-HSA-9727305 mRNA8 is translated to protein 8 TAS Homo sapiens 8756 R-HSA-9754745 https://reactome.org/PathwayBrowser/#/R-HSA-9754745 IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 8756 R-HSA-9755252 https://reactome.org/PathwayBrowser/#/R-HSA-9755252 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 8756 R-HSA-9755258 https://reactome.org/PathwayBrowser/#/R-HSA-9755258 DDX58 binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 8756 R-HSA-9755368 https://reactome.org/PathwayBrowser/#/R-HSA-9755368 TLR2:TLR1 binds SARS-CoV-2 E pentamer TAS Homo sapiens 8756 R-HSA-9756574 https://reactome.org/PathwayBrowser/#/R-HSA-9756574 SARS-CoV-2 S binds SFTPD 12mer TAS Homo sapiens 8756 R-HSA-9759709 https://reactome.org/PathwayBrowser/#/R-HSA-9759709 CNBP binds SARS-CoV-2 G-rich RNA TAS Homo sapiens 8756 R-HSA-9760510 https://reactome.org/PathwayBrowser/#/R-HSA-9760510 LARP1 binds SARS-CoV-2 RNA TAS Homo sapiens 8756 R-HSA-9769949 https://reactome.org/PathwayBrowser/#/R-HSA-9769949 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage TAS Homo sapiens 87715 R-BTA-417829 https://reactome.org/PathwayBrowser/#/R-BTA-417829 P2RY12 binds ADP IEA Bos taurus 87715 R-BTA-9611277 https://reactome.org/PathwayBrowser/#/R-BTA-9611277 P2RY12 binds P2RY12 antagonists IEA Bos taurus 87715 R-CFA-417829 https://reactome.org/PathwayBrowser/#/R-CFA-417829 P2RY12 binds ADP IEA Canis familiaris 87715 R-CFA-9611277 https://reactome.org/PathwayBrowser/#/R-CFA-9611277 P2RY12 binds P2RY12 antagonists IEA Canis familiaris 87715 R-DRE-417829 https://reactome.org/PathwayBrowser/#/R-DRE-417829 P2RY12 binds ADP IEA Danio rerio 87715 R-DRE-9611277 https://reactome.org/PathwayBrowser/#/R-DRE-9611277 P2RY12 binds P2RY12 antagonists IEA Danio rerio 87715 R-HSA-417829 https://reactome.org/PathwayBrowser/#/R-HSA-417829 P2RY12 binds ADP TAS Homo sapiens 87715 R-HSA-9611277 https://reactome.org/PathwayBrowser/#/R-HSA-9611277 P2RY12 binds P2RY12 antagonists TAS Homo sapiens 87715 R-MMU-417829 https://reactome.org/PathwayBrowser/#/R-MMU-417829 P2RY12 binds ADP IEA Mus musculus 87715 R-MMU-9611277 https://reactome.org/PathwayBrowser/#/R-MMU-9611277 P2RY12 binds P2RY12 antagonists IEA Mus musculus 87715 R-RNO-417829 https://reactome.org/PathwayBrowser/#/R-RNO-417829 P2RY12 binds ADP IEA Rattus norvegicus 87715 R-RNO-9611277 https://reactome.org/PathwayBrowser/#/R-RNO-9611277 P2RY12 binds P2RY12 antagonists IEA Rattus norvegicus 87715 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa 87715 R-SSC-9611277 https://reactome.org/PathwayBrowser/#/R-SSC-9611277 P2RY12 binds P2RY12 antagonists IEA Sus scrofa 87715 R-XTR-417829 https://reactome.org/PathwayBrowser/#/R-XTR-417829 P2RY12 binds ADP IEA Xenopus tropicalis 87715 R-XTR-9611277 https://reactome.org/PathwayBrowser/#/R-XTR-9611277 P2RY12 binds P2RY12 antagonists IEA Xenopus tropicalis 8774 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 8774 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 8774 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 8774 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 8774 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 8774 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 8774 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 8774 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 8774 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 8774 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 8774 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 8774 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 87752 R-BTA-5692232 https://reactome.org/PathwayBrowser/#/R-BTA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Bos taurus 87752 R-CEL-5692232 https://reactome.org/PathwayBrowser/#/R-CEL-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Caenorhabditis elegans 87752 R-CFA-5692232 https://reactome.org/PathwayBrowser/#/R-CFA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Canis familiaris 87752 R-DDI-5692232 https://reactome.org/PathwayBrowser/#/R-DDI-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Dictyostelium discoideum 87752 R-DME-5692232 https://reactome.org/PathwayBrowser/#/R-DME-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Drosophila melanogaster 87752 R-DRE-5692232 https://reactome.org/PathwayBrowser/#/R-DRE-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Danio rerio 87752 R-GGA-5692232 https://reactome.org/PathwayBrowser/#/R-GGA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Gallus gallus 87752 R-HSA-5692232 https://reactome.org/PathwayBrowser/#/R-HSA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione TAS Homo sapiens 87752 R-MMU-5692232 https://reactome.org/PathwayBrowser/#/R-MMU-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Mus musculus 87752 R-RNO-5692232 https://reactome.org/PathwayBrowser/#/R-RNO-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Rattus norvegicus 87752 R-SCE-5692232 https://reactome.org/PathwayBrowser/#/R-SCE-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Saccharomyces cerevisiae 87752 R-SPO-5692232 https://reactome.org/PathwayBrowser/#/R-SPO-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Schizosaccharomyces pombe 87752 R-SSC-5692232 https://reactome.org/PathwayBrowser/#/R-SSC-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Sus scrofa 87752 R-XTR-5692232 https://reactome.org/PathwayBrowser/#/R-XTR-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione IEA Xenopus tropicalis 87785 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 87785 R-BTA-9845516 https://reactome.org/PathwayBrowser/#/R-BTA-9845516 B3GALT4 transfers Gal to gangliosides IEA Bos taurus 87785 R-BTA-9845538 https://reactome.org/PathwayBrowser/#/R-BTA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Bos taurus 87785 R-CEL-9845516 https://reactome.org/PathwayBrowser/#/R-CEL-9845516 B3GALT4 transfers Gal to gangliosides IEA Caenorhabditis elegans 87785 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 87785 R-CFA-9845516 https://reactome.org/PathwayBrowser/#/R-CFA-9845516 B3GALT4 transfers Gal to gangliosides IEA Canis familiaris 87785 R-CFA-9845538 https://reactome.org/PathwayBrowser/#/R-CFA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Canis familiaris 87785 R-DME-9845516 https://reactome.org/PathwayBrowser/#/R-DME-9845516 B3GALT4 transfers Gal to gangliosides IEA Drosophila melanogaster 87785 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 87785 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 87785 R-GGA-9845538 https://reactome.org/PathwayBrowser/#/R-GGA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Gallus gallus 87785 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 87785 R-HSA-9845516 https://reactome.org/PathwayBrowser/#/R-HSA-9845516 B3GALT4 transfers Gal to gangliosides TAS Homo sapiens 87785 R-HSA-9845538 https://reactome.org/PathwayBrowser/#/R-HSA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides TAS Homo sapiens 87785 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 87785 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 87785 R-MMU-9845516 https://reactome.org/PathwayBrowser/#/R-MMU-9845516 B3GALT4 transfers Gal to gangliosides IEA Mus musculus 87785 R-MMU-9845538 https://reactome.org/PathwayBrowser/#/R-MMU-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Mus musculus 87785 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 87785 R-RNO-9845516 https://reactome.org/PathwayBrowser/#/R-RNO-9845516 B3GALT4 transfers Gal to gangliosides IEA Rattus norvegicus 87785 R-RNO-9845538 https://reactome.org/PathwayBrowser/#/R-RNO-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Rattus norvegicus 87785 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 87785 R-SSC-9845516 https://reactome.org/PathwayBrowser/#/R-SSC-9845516 B3GALT4 transfers Gal to gangliosides IEA Sus scrofa 87785 R-SSC-9845538 https://reactome.org/PathwayBrowser/#/R-SSC-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Sus scrofa 87785 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 87785 R-XTR-9845516 https://reactome.org/PathwayBrowser/#/R-XTR-9845516 B3GALT4 transfers Gal to gangliosides IEA Xenopus tropicalis 87785 R-XTR-9845538 https://reactome.org/PathwayBrowser/#/R-XTR-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Xenopus tropicalis 87787 R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 87787 R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 87787 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 87787 R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 87787 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 87787 R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 87787 R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 87787 R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 87787 R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 87788 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 87788 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 87788 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 87788 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 87788 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 87788 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 87788 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 87788 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 87788 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 87792 R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 87792 R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 87792 R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 87792 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 87792 R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 87792 R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 87792 R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 87792 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 87792 R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 8805 R-BTA-9650858 https://reactome.org/PathwayBrowser/#/R-BTA-9650858 Meglitinides bind ABCC8 IEA Bos taurus 8805 R-CFA-9650858 https://reactome.org/PathwayBrowser/#/R-CFA-9650858 Meglitinides bind ABCC8 IEA Canis familiaris 8805 R-DME-9650858 https://reactome.org/PathwayBrowser/#/R-DME-9650858 Meglitinides bind ABCC8 IEA Drosophila melanogaster 8805 R-GGA-9650858 https://reactome.org/PathwayBrowser/#/R-GGA-9650858 Meglitinides bind ABCC8 IEA Gallus gallus 8805 R-HSA-9650858 https://reactome.org/PathwayBrowser/#/R-HSA-9650858 Meglitinides bind ABCC8 TAS Homo sapiens 8805 R-MMU-9650858 https://reactome.org/PathwayBrowser/#/R-MMU-9650858 Meglitinides bind ABCC8 IEA Mus musculus 8805 R-RNO-9650858 https://reactome.org/PathwayBrowser/#/R-RNO-9650858 Meglitinides bind ABCC8 IEA Rattus norvegicus 8805 R-SSC-9650858 https://reactome.org/PathwayBrowser/#/R-SSC-9650858 Meglitinides bind ABCC8 IEA Sus scrofa 8805 R-XTR-9650858 https://reactome.org/PathwayBrowser/#/R-XTR-9650858 Meglitinides bind ABCC8 IEA Xenopus tropicalis 88069 R-BTA-1605717 https://reactome.org/PathwayBrowser/#/R-BTA-1605717 GM2A binds and mobilizes ligands IEA Bos taurus 88069 R-BTA-9840795 https://reactome.org/PathwayBrowser/#/R-BTA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Bos taurus 88069 R-BTA-9846332 https://reactome.org/PathwayBrowser/#/R-BTA-9846332 FUT1,2 transfer fucose to gangliosides IEA Bos taurus 88069 R-CEL-1605717 https://reactome.org/PathwayBrowser/#/R-CEL-1605717 GM2A binds and mobilizes ligands IEA Caenorhabditis elegans 88069 R-CEL-9840795 https://reactome.org/PathwayBrowser/#/R-CEL-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Caenorhabditis elegans 88069 R-CEL-9846332 https://reactome.org/PathwayBrowser/#/R-CEL-9846332 FUT1,2 transfer fucose to gangliosides IEA Caenorhabditis elegans 88069 R-CFA-1605717 https://reactome.org/PathwayBrowser/#/R-CFA-1605717 GM2A binds and mobilizes ligands IEA Canis familiaris 88069 R-CFA-9840795 https://reactome.org/PathwayBrowser/#/R-CFA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Canis familiaris 88069 R-CFA-9846332 https://reactome.org/PathwayBrowser/#/R-CFA-9846332 FUT1,2 transfer fucose to gangliosides IEA Canis familiaris 88069 R-HSA-1605717 https://reactome.org/PathwayBrowser/#/R-HSA-1605717 GM2A binds and mobilizes ligands TAS Homo sapiens 88069 R-HSA-9840795 https://reactome.org/PathwayBrowser/#/R-HSA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 TAS Homo sapiens 88069 R-HSA-9846332 https://reactome.org/PathwayBrowser/#/R-HSA-9846332 FUT1,2 transfer fucose to gangliosides TAS Homo sapiens 88069 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 88069 R-MMU-1605717 https://reactome.org/PathwayBrowser/#/R-MMU-1605717 GM2A binds and mobilizes ligands IEA Mus musculus 88069 R-MMU-9840795 https://reactome.org/PathwayBrowser/#/R-MMU-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Mus musculus 88069 R-MMU-9846332 https://reactome.org/PathwayBrowser/#/R-MMU-9846332 FUT1,2 transfer fucose to gangliosides IEA Mus musculus 88069 R-RNO-1605717 https://reactome.org/PathwayBrowser/#/R-RNO-1605717 GM2A binds and mobilizes ligands IEA Rattus norvegicus 88069 R-RNO-9840795 https://reactome.org/PathwayBrowser/#/R-RNO-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Rattus norvegicus 88069 R-RNO-9846332 https://reactome.org/PathwayBrowser/#/R-RNO-9846332 FUT1,2 transfer fucose to gangliosides IEA Rattus norvegicus 88069 R-SSC-1605717 https://reactome.org/PathwayBrowser/#/R-SSC-1605717 GM2A binds and mobilizes ligands IEA Sus scrofa 88069 R-SSC-9840795 https://reactome.org/PathwayBrowser/#/R-SSC-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Sus scrofa 88069 R-SSC-9846332 https://reactome.org/PathwayBrowser/#/R-SSC-9846332 FUT1,2 transfer fucose to gangliosides IEA Sus scrofa 88069 R-XTR-1605717 https://reactome.org/PathwayBrowser/#/R-XTR-1605717 GM2A binds and mobilizes ligands IEA Xenopus tropicalis 88069 R-XTR-9840795 https://reactome.org/PathwayBrowser/#/R-XTR-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Xenopus tropicalis 88069 R-XTR-9846332 https://reactome.org/PathwayBrowser/#/R-XTR-9846332 FUT1,2 transfer fucose to gangliosides IEA Xenopus tropicalis 88130 R-BTA-6803771 https://reactome.org/PathwayBrowser/#/R-BTA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Bos taurus 88130 R-BTA-6803789 https://reactome.org/PathwayBrowser/#/R-BTA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Bos taurus 88130 R-CEL-6803771 https://reactome.org/PathwayBrowser/#/R-CEL-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Caenorhabditis elegans 88130 R-CEL-6803789 https://reactome.org/PathwayBrowser/#/R-CEL-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Caenorhabditis elegans 88130 R-CFA-6803771 https://reactome.org/PathwayBrowser/#/R-CFA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Canis familiaris 88130 R-CFA-6803789 https://reactome.org/PathwayBrowser/#/R-CFA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Canis familiaris 88130 R-DME-6803771 https://reactome.org/PathwayBrowser/#/R-DME-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Drosophila melanogaster 88130 R-DME-6803789 https://reactome.org/PathwayBrowser/#/R-DME-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Drosophila melanogaster 88130 R-DRE-6803789 https://reactome.org/PathwayBrowser/#/R-DRE-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Danio rerio 88130 R-GGA-6803771 https://reactome.org/PathwayBrowser/#/R-GGA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Gallus gallus 88130 R-GGA-6803789 https://reactome.org/PathwayBrowser/#/R-GGA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Gallus gallus 88130 R-HSA-6803771 https://reactome.org/PathwayBrowser/#/R-HSA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P TAS Homo sapiens 88130 R-HSA-6803789 https://reactome.org/PathwayBrowser/#/R-HSA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA TAS Homo sapiens 88130 R-MMU-6803771 https://reactome.org/PathwayBrowser/#/R-MMU-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Mus musculus 88130 R-MMU-6803789 https://reactome.org/PathwayBrowser/#/R-MMU-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Mus musculus 88130 R-RNO-6803771 https://reactome.org/PathwayBrowser/#/R-RNO-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Rattus norvegicus 88130 R-RNO-6803789 https://reactome.org/PathwayBrowser/#/R-RNO-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Rattus norvegicus 88130 R-SSC-6803771 https://reactome.org/PathwayBrowser/#/R-SSC-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Sus scrofa 88130 R-SSC-6803789 https://reactome.org/PathwayBrowser/#/R-SSC-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Sus scrofa 88130 R-XTR-6803789 https://reactome.org/PathwayBrowser/#/R-XTR-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Xenopus tropicalis 88154 R-BTA-1605632 https://reactome.org/PathwayBrowser/#/R-BTA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Bos taurus 88154 R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus 88154 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 88154 R-CEL-1605632 https://reactome.org/PathwayBrowser/#/R-CEL-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Caenorhabditis elegans 88154 R-CEL-1605736 https://reactome.org/PathwayBrowser/#/R-CEL-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Caenorhabditis elegans 88154 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 88154 R-CFA-1605632 https://reactome.org/PathwayBrowser/#/R-CFA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Canis familiaris 88154 R-CFA-1605736 https://reactome.org/PathwayBrowser/#/R-CFA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Canis familiaris 88154 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 88154 R-DDI-1605632 https://reactome.org/PathwayBrowser/#/R-DDI-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Dictyostelium discoideum 88154 R-DDI-1605736 https://reactome.org/PathwayBrowser/#/R-DDI-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Dictyostelium discoideum 88154 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 88154 R-DME-1605632 https://reactome.org/PathwayBrowser/#/R-DME-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Drosophila melanogaster 88154 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 88154 R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus 88154 R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus 88154 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 88154 R-HSA-1605632 https://reactome.org/PathwayBrowser/#/R-HSA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE TAS Homo sapiens 88154 R-HSA-1605736 https://reactome.org/PathwayBrowser/#/R-HSA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE TAS Homo sapiens 88154 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 88154 R-MMU-1605632 https://reactome.org/PathwayBrowser/#/R-MMU-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Mus musculus 88154 R-MMU-1605736 https://reactome.org/PathwayBrowser/#/R-MMU-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Mus musculus 88154 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 88154 R-RNO-1605632 https://reactome.org/PathwayBrowser/#/R-RNO-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Rattus norvegicus 88154 R-RNO-1605736 https://reactome.org/PathwayBrowser/#/R-RNO-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Rattus norvegicus 88154 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 88154 R-SSC-1605632 https://reactome.org/PathwayBrowser/#/R-SSC-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Sus scrofa 88154 R-SSC-1605736 https://reactome.org/PathwayBrowser/#/R-SSC-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Sus scrofa 88154 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 88167 R-BTA-1605632 https://reactome.org/PathwayBrowser/#/R-BTA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Bos taurus 88167 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 88167 R-CEL-1605632 https://reactome.org/PathwayBrowser/#/R-CEL-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Caenorhabditis elegans 88167 R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 88167 R-CFA-1605632 https://reactome.org/PathwayBrowser/#/R-CFA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Canis familiaris 88167 R-CFA-8878914 https://reactome.org/PathwayBrowser/#/R-CFA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Canis familiaris 88167 R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 88167 R-DDI-1605632 https://reactome.org/PathwayBrowser/#/R-DDI-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Dictyostelium discoideum 88167 R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 88167 R-DME-1605632 https://reactome.org/PathwayBrowser/#/R-DME-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Drosophila melanogaster 88167 R-DME-8878914 https://reactome.org/PathwayBrowser/#/R-DME-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Drosophila melanogaster 88167 R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 88167 R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus 88167 R-GGA-8878914 https://reactome.org/PathwayBrowser/#/R-GGA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Gallus gallus 88167 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 88167 R-HSA-1605632 https://reactome.org/PathwayBrowser/#/R-HSA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE TAS Homo sapiens 88167 R-HSA-8878914 https://reactome.org/PathwayBrowser/#/R-HSA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer TAS Homo sapiens 88167 R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 88167 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 88167 R-MMU-1605632 https://reactome.org/PathwayBrowser/#/R-MMU-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Mus musculus 88167 R-MMU-8878914 https://reactome.org/PathwayBrowser/#/R-MMU-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Mus musculus 88167 R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 88167 R-RNO-1605632 https://reactome.org/PathwayBrowser/#/R-RNO-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Rattus norvegicus 88167 R-RNO-8878914 https://reactome.org/PathwayBrowser/#/R-RNO-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Rattus norvegicus 88167 R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 88167 R-SSC-1605632 https://reactome.org/PathwayBrowser/#/R-SSC-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Sus scrofa 88167 R-SSC-8878914 https://reactome.org/PathwayBrowser/#/R-SSC-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Sus scrofa 88167 R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 88200 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 88200 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 88200 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 88200 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 88200 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 88200 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 88200 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 88200 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 88200 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 88200 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 88200 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 88200 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 88200 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 88200 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 88200 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 88200 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 88200 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 88200 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 88200 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 88200 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 88200 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 88200 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 88200 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 88200 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 88200 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 88200 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 88200 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 88200 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 88200 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 88200 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 88200 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 88200 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 88200 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 88219 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 88219 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 88219 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 88219 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 88219 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 88219 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 88219 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 88249 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 88249 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 88249 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 88249 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 88249 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 88249 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 88249 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 88249 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 88249 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 88249 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 88249 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 88249 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 88249 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 88249 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 88249 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 88249 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 88249 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 88249 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 8869 R-CEL-9717841 https://reactome.org/PathwayBrowser/#/R-CEL-9717841 holo-FDPS dimer binds NBPs IEA Caenorhabditis elegans 8869 R-CFA-9717841 https://reactome.org/PathwayBrowser/#/R-CFA-9717841 holo-FDPS dimer binds NBPs IEA Canis familiaris 8869 R-DDI-9717841 https://reactome.org/PathwayBrowser/#/R-DDI-9717841 holo-FDPS dimer binds NBPs IEA Dictyostelium discoideum 8869 R-DME-9717841 https://reactome.org/PathwayBrowser/#/R-DME-9717841 holo-FDPS dimer binds NBPs IEA Drosophila melanogaster 8869 R-DRE-9717841 https://reactome.org/PathwayBrowser/#/R-DRE-9717841 holo-FDPS dimer binds NBPs IEA Danio rerio 8869 R-GGA-9717841 https://reactome.org/PathwayBrowser/#/R-GGA-9717841 holo-FDPS dimer binds NBPs IEA Gallus gallus 8869 R-HSA-9717841 https://reactome.org/PathwayBrowser/#/R-HSA-9717841 holo-FDPS dimer binds NBPs TAS Homo sapiens 8869 R-MMU-9717841 https://reactome.org/PathwayBrowser/#/R-MMU-9717841 holo-FDPS dimer binds NBPs IEA Mus musculus 8869 R-PFA-9717841 https://reactome.org/PathwayBrowser/#/R-PFA-9717841 holo-FDPS dimer binds NBPs IEA Plasmodium falciparum 8869 R-RNO-9717841 https://reactome.org/PathwayBrowser/#/R-RNO-9717841 holo-FDPS dimer binds NBPs IEA Rattus norvegicus 8869 R-SCE-9717841 https://reactome.org/PathwayBrowser/#/R-SCE-9717841 holo-FDPS dimer binds NBPs IEA Saccharomyces cerevisiae 8869 R-SPO-9717841 https://reactome.org/PathwayBrowser/#/R-SPO-9717841 holo-FDPS dimer binds NBPs IEA Schizosaccharomyces pombe 8869 R-SSC-9717841 https://reactome.org/PathwayBrowser/#/R-SSC-9717841 holo-FDPS dimer binds NBPs IEA Sus scrofa 8874 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 8874 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 8874 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 8874 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 8874 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 8874 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 8874 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 8874 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 8874 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 8874 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 8874 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 8874 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 8874 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 8874 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 8874 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 88742 R-BTA-9750001 https://reactome.org/PathwayBrowser/#/R-BTA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Bos taurus 88742 R-BTA-9750656 https://reactome.org/PathwayBrowser/#/R-BTA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Bos taurus 88742 R-CEL-9750001 https://reactome.org/PathwayBrowser/#/R-CEL-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Caenorhabditis elegans 88742 R-CEL-9750656 https://reactome.org/PathwayBrowser/#/R-CEL-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Caenorhabditis elegans 88742 R-CFA-9750001 https://reactome.org/PathwayBrowser/#/R-CFA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Canis familiaris 88742 R-CFA-9750656 https://reactome.org/PathwayBrowser/#/R-CFA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Canis familiaris 88742 R-DDI-9750656 https://reactome.org/PathwayBrowser/#/R-DDI-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Dictyostelium discoideum 88742 R-DME-9750656 https://reactome.org/PathwayBrowser/#/R-DME-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Drosophila melanogaster 88742 R-DRE-9750656 https://reactome.org/PathwayBrowser/#/R-DRE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Danio rerio 88742 R-GGA-9750001 https://reactome.org/PathwayBrowser/#/R-GGA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Gallus gallus 88742 R-GGA-9750656 https://reactome.org/PathwayBrowser/#/R-GGA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Gallus gallus 88742 R-HSA-9750001 https://reactome.org/PathwayBrowser/#/R-HSA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid TAS Homo sapiens 88742 R-HSA-9750656 https://reactome.org/PathwayBrowser/#/R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells TAS Homo sapiens 88742 R-HSA-9750660 https://reactome.org/PathwayBrowser/#/R-HSA-9750660 Glycine conjugates translocates from mitochondrial matrix to cytosol TAS Homo sapiens 88742 R-MMU-9750001 https://reactome.org/PathwayBrowser/#/R-MMU-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Mus musculus 88742 R-MMU-9750656 https://reactome.org/PathwayBrowser/#/R-MMU-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Mus musculus 88742 R-RNO-9750001 https://reactome.org/PathwayBrowser/#/R-RNO-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Rattus norvegicus 88742 R-RNO-9750656 https://reactome.org/PathwayBrowser/#/R-RNO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Rattus norvegicus 88742 R-SCE-9750656 https://reactome.org/PathwayBrowser/#/R-SCE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Saccharomyces cerevisiae 88742 R-SPO-9750656 https://reactome.org/PathwayBrowser/#/R-SPO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Schizosaccharomyces pombe 88742 R-SSC-9750001 https://reactome.org/PathwayBrowser/#/R-SSC-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Sus scrofa 88742 R-SSC-9750656 https://reactome.org/PathwayBrowser/#/R-SSC-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Sus scrofa 88742 R-XTR-9750001 https://reactome.org/PathwayBrowser/#/R-XTR-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Xenopus tropicalis 88742 R-XTR-9750656 https://reactome.org/PathwayBrowser/#/R-XTR-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Xenopus tropicalis 8887 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 8887 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 8887 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 8887 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 8887 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 8887 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 8887 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 8887 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 8887 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 8887 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 8887 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 8887 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 8887 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 8887 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 8887 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 8887 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 8887 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 8887 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 89886 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 89886 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 89886 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 89886 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 89886 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 89886 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 89886 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 89886 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 89886 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 9008 R-BTA-159574 https://reactome.org/PathwayBrowser/#/R-BTA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Bos taurus 9008 R-BTA-9750656 https://reactome.org/PathwayBrowser/#/R-BTA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Bos taurus 9008 R-CEL-159574 https://reactome.org/PathwayBrowser/#/R-CEL-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Caenorhabditis elegans 9008 R-CEL-9750656 https://reactome.org/PathwayBrowser/#/R-CEL-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Caenorhabditis elegans 9008 R-CFA-159574 https://reactome.org/PathwayBrowser/#/R-CFA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Canis familiaris 9008 R-CFA-9750656 https://reactome.org/PathwayBrowser/#/R-CFA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Canis familiaris 9008 R-DDI-9750656 https://reactome.org/PathwayBrowser/#/R-DDI-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Dictyostelium discoideum 9008 R-DME-9750656 https://reactome.org/PathwayBrowser/#/R-DME-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Drosophila melanogaster 9008 R-DRE-9750656 https://reactome.org/PathwayBrowser/#/R-DRE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Danio rerio 9008 R-GGA-159574 https://reactome.org/PathwayBrowser/#/R-GGA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Gallus gallus 9008 R-GGA-9750656 https://reactome.org/PathwayBrowser/#/R-GGA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Gallus gallus 9008 R-HSA-159574 https://reactome.org/PathwayBrowser/#/R-HSA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA TAS Homo sapiens 9008 R-HSA-9750656 https://reactome.org/PathwayBrowser/#/R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells TAS Homo sapiens 9008 R-HSA-9750660 https://reactome.org/PathwayBrowser/#/R-HSA-9750660 Glycine conjugates translocates from mitochondrial matrix to cytosol TAS Homo sapiens 9008 R-MMU-159574 https://reactome.org/PathwayBrowser/#/R-MMU-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Mus musculus 9008 R-MMU-9750656 https://reactome.org/PathwayBrowser/#/R-MMU-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Mus musculus 9008 R-RNO-159574 https://reactome.org/PathwayBrowser/#/R-RNO-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Rattus norvegicus 9008 R-RNO-9750656 https://reactome.org/PathwayBrowser/#/R-RNO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Rattus norvegicus 9008 R-SCE-9750656 https://reactome.org/PathwayBrowser/#/R-SCE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Saccharomyces cerevisiae 9008 R-SPO-9750656 https://reactome.org/PathwayBrowser/#/R-SPO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Schizosaccharomyces pombe 9008 R-SSC-159574 https://reactome.org/PathwayBrowser/#/R-SSC-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Sus scrofa 9008 R-SSC-9750656 https://reactome.org/PathwayBrowser/#/R-SSC-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Sus scrofa 9008 R-XTR-159574 https://reactome.org/PathwayBrowser/#/R-XTR-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Xenopus tropicalis 9008 R-XTR-9750656 https://reactome.org/PathwayBrowser/#/R-XTR-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Xenopus tropicalis 90152 R-BTA-159752 https://reactome.org/PathwayBrowser/#/R-BTA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Bos taurus 90152 R-BTA-159761 https://reactome.org/PathwayBrowser/#/R-BTA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Bos taurus 90152 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 90152 R-BTA-159795 https://reactome.org/PathwayBrowser/#/R-BTA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Bos taurus 90152 R-BTA-159803 https://reactome.org/PathwayBrowser/#/R-BTA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Bos taurus 90152 R-BTA-159819 https://reactome.org/PathwayBrowser/#/R-BTA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Bos taurus 90152 R-BTA-159826 https://reactome.org/PathwayBrowser/#/R-BTA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Bos taurus 90152 R-BTA-163820 https://reactome.org/PathwayBrowser/#/R-BTA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Bos taurus 90152 R-BTA-6806647 https://reactome.org/PathwayBrowser/#/R-BTA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 90152 R-BTA-6807214 https://reactome.org/PathwayBrowser/#/R-BTA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Bos taurus 90152 R-CFA-159752 https://reactome.org/PathwayBrowser/#/R-CFA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Canis familiaris 90152 R-CFA-159761 https://reactome.org/PathwayBrowser/#/R-CFA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Canis familiaris 90152 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 90152 R-CFA-159795 https://reactome.org/PathwayBrowser/#/R-CFA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Canis familiaris 90152 R-CFA-159803 https://reactome.org/PathwayBrowser/#/R-CFA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Canis familiaris 90152 R-CFA-159819 https://reactome.org/PathwayBrowser/#/R-CFA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Canis familiaris 90152 R-CFA-159826 https://reactome.org/PathwayBrowser/#/R-CFA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Canis familiaris 90152 R-CFA-6806647 https://reactome.org/PathwayBrowser/#/R-CFA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 90152 R-CFA-6807214 https://reactome.org/PathwayBrowser/#/R-CFA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Canis familiaris 90152 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 90152 R-DRE-6806647 https://reactome.org/PathwayBrowser/#/R-DRE-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Danio rerio 90152 R-GGA-6806647 https://reactome.org/PathwayBrowser/#/R-GGA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Gallus gallus 90152 R-HSA-159752 https://reactome.org/PathwayBrowser/#/R-HSA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) TAS Homo sapiens 90152 R-HSA-159761 https://reactome.org/PathwayBrowser/#/R-HSA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) TAS Homo sapiens 90152 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 90152 R-HSA-159795 https://reactome.org/PathwayBrowser/#/R-HSA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) TAS Homo sapiens 90152 R-HSA-159803 https://reactome.org/PathwayBrowser/#/R-HSA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) TAS Homo sapiens 90152 R-HSA-159819 https://reactome.org/PathwayBrowser/#/R-HSA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) TAS Homo sapiens 90152 R-HSA-159826 https://reactome.org/PathwayBrowser/#/R-HSA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) TAS Homo sapiens 90152 R-HSA-163810 https://reactome.org/PathwayBrowser/#/R-HSA-163810 GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6) IEA Homo sapiens 90152 R-HSA-163820 https://reactome.org/PathwayBrowser/#/R-HSA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) TAS Homo sapiens 90152 R-HSA-6806647 https://reactome.org/PathwayBrowser/#/R-HSA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 90152 R-HSA-6807214 https://reactome.org/PathwayBrowser/#/R-HSA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) TAS Homo sapiens 90152 R-MMU-159752 https://reactome.org/PathwayBrowser/#/R-MMU-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Mus musculus 90152 R-MMU-159761 https://reactome.org/PathwayBrowser/#/R-MMU-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Mus musculus 90152 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 90152 R-MMU-159795 https://reactome.org/PathwayBrowser/#/R-MMU-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Mus musculus 90152 R-MMU-159803 https://reactome.org/PathwayBrowser/#/R-MMU-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Mus musculus 90152 R-MMU-159819 https://reactome.org/PathwayBrowser/#/R-MMU-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Mus musculus 90152 R-MMU-159826 https://reactome.org/PathwayBrowser/#/R-MMU-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Mus musculus 90152 R-MMU-163820 https://reactome.org/PathwayBrowser/#/R-MMU-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Mus musculus 90152 R-MMU-6806647 https://reactome.org/PathwayBrowser/#/R-MMU-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 90152 R-MMU-6807214 https://reactome.org/PathwayBrowser/#/R-MMU-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Mus musculus 90152 R-RNO-159752 https://reactome.org/PathwayBrowser/#/R-RNO-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Rattus norvegicus 90152 R-RNO-159761 https://reactome.org/PathwayBrowser/#/R-RNO-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Rattus norvegicus 90152 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 90152 R-RNO-159795 https://reactome.org/PathwayBrowser/#/R-RNO-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Rattus norvegicus 90152 R-RNO-159803 https://reactome.org/PathwayBrowser/#/R-RNO-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Rattus norvegicus 90152 R-RNO-159819 https://reactome.org/PathwayBrowser/#/R-RNO-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Rattus norvegicus 90152 R-RNO-159826 https://reactome.org/PathwayBrowser/#/R-RNO-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Rattus norvegicus 90152 R-RNO-163820 https://reactome.org/PathwayBrowser/#/R-RNO-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Rattus norvegicus 90152 R-RNO-6806647 https://reactome.org/PathwayBrowser/#/R-RNO-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 90152 R-RNO-6807214 https://reactome.org/PathwayBrowser/#/R-RNO-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Rattus norvegicus 90152 R-SSC-159752 https://reactome.org/PathwayBrowser/#/R-SSC-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Sus scrofa 90152 R-SSC-159761 https://reactome.org/PathwayBrowser/#/R-SSC-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Sus scrofa 90152 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 90152 R-SSC-159795 https://reactome.org/PathwayBrowser/#/R-SSC-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Sus scrofa 90152 R-SSC-159803 https://reactome.org/PathwayBrowser/#/R-SSC-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Sus scrofa 90152 R-SSC-159819 https://reactome.org/PathwayBrowser/#/R-SSC-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Sus scrofa 90152 R-SSC-159826 https://reactome.org/PathwayBrowser/#/R-SSC-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Sus scrofa 90152 R-SSC-6806647 https://reactome.org/PathwayBrowser/#/R-SSC-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 90152 R-SSC-6807214 https://reactome.org/PathwayBrowser/#/R-SSC-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Sus scrofa 90152 R-XTR-159752 https://reactome.org/PathwayBrowser/#/R-XTR-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Xenopus tropicalis 90152 R-XTR-159761 https://reactome.org/PathwayBrowser/#/R-XTR-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Xenopus tropicalis 90152 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 90152 R-XTR-159795 https://reactome.org/PathwayBrowser/#/R-XTR-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Xenopus tropicalis 90152 R-XTR-159803 https://reactome.org/PathwayBrowser/#/R-XTR-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Xenopus tropicalis 90152 R-XTR-159819 https://reactome.org/PathwayBrowser/#/R-XTR-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Xenopus tropicalis 90152 R-XTR-159826 https://reactome.org/PathwayBrowser/#/R-XTR-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Xenopus tropicalis 90152 R-XTR-163820 https://reactome.org/PathwayBrowser/#/R-XTR-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Xenopus tropicalis 90152 R-XTR-6806647 https://reactome.org/PathwayBrowser/#/R-XTR-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 90152 R-XTR-6807214 https://reactome.org/PathwayBrowser/#/R-XTR-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Xenopus tropicalis 90163 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 90163 R-BTA-9840884 https://reactome.org/PathwayBrowser/#/R-BTA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Bos taurus 90163 R-BTA-9840949 https://reactome.org/PathwayBrowser/#/R-BTA-9840949 ARSA removes sulfate from SM3 IEA Bos taurus 90163 R-BTA-9844587 https://reactome.org/PathwayBrowser/#/R-BTA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Bos taurus 90163 R-CEL-9840884 https://reactome.org/PathwayBrowser/#/R-CEL-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Caenorhabditis elegans 90163 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 90163 R-CFA-9840884 https://reactome.org/PathwayBrowser/#/R-CFA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Canis familiaris 90163 R-CFA-9840949 https://reactome.org/PathwayBrowser/#/R-CFA-9840949 ARSA removes sulfate from SM3 IEA Canis familiaris 90163 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 90163 R-DRE-9844587 https://reactome.org/PathwayBrowser/#/R-DRE-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Danio rerio 90163 R-GGA-9840949 https://reactome.org/PathwayBrowser/#/R-GGA-9840949 ARSA removes sulfate from SM3 IEA Gallus gallus 90163 R-GGA-9844587 https://reactome.org/PathwayBrowser/#/R-GGA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Gallus gallus 90163 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 90163 R-HSA-9840884 https://reactome.org/PathwayBrowser/#/R-HSA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 TAS Homo sapiens 90163 R-HSA-9840949 https://reactome.org/PathwayBrowser/#/R-HSA-9840949 ARSA removes sulfate from SM3 TAS Homo sapiens 90163 R-HSA-9844587 https://reactome.org/PathwayBrowser/#/R-HSA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer TAS Homo sapiens 90163 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 90163 R-MMU-9840884 https://reactome.org/PathwayBrowser/#/R-MMU-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Mus musculus 90163 R-MMU-9840949 https://reactome.org/PathwayBrowser/#/R-MMU-9840949 ARSA removes sulfate from SM3 IEA Mus musculus 90163 R-MMU-9844587 https://reactome.org/PathwayBrowser/#/R-MMU-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Mus musculus 90163 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 90163 R-RNO-9840884 https://reactome.org/PathwayBrowser/#/R-RNO-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Rattus norvegicus 90163 R-RNO-9840949 https://reactome.org/PathwayBrowser/#/R-RNO-9840949 ARSA removes sulfate from SM3 IEA Rattus norvegicus 90163 R-RNO-9844587 https://reactome.org/PathwayBrowser/#/R-RNO-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Rattus norvegicus 90163 R-SPO-9840949 https://reactome.org/PathwayBrowser/#/R-SPO-9840949 ARSA removes sulfate from SM3 IEA Schizosaccharomyces pombe 90163 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 90163 R-SSC-9840884 https://reactome.org/PathwayBrowser/#/R-SSC-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Sus scrofa 90163 R-SSC-9840949 https://reactome.org/PathwayBrowser/#/R-SSC-9840949 ARSA removes sulfate from SM3 IEA Sus scrofa 90163 R-SSC-9844587 https://reactome.org/PathwayBrowser/#/R-SSC-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Sus scrofa 90163 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 90163 R-XTR-9840949 https://reactome.org/PathwayBrowser/#/R-XTR-9840949 ARSA removes sulfate from SM3 IEA Xenopus tropicalis 90163 R-XTR-9844587 https://reactome.org/PathwayBrowser/#/R-XTR-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Xenopus tropicalis 90164 R-BTA-1605717 https://reactome.org/PathwayBrowser/#/R-BTA-1605717 GM2A binds and mobilizes ligands IEA Bos taurus 90164 R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 90164 R-BTA-9840884 https://reactome.org/PathwayBrowser/#/R-BTA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Bos taurus 90164 R-CEL-1605717 https://reactome.org/PathwayBrowser/#/R-CEL-1605717 GM2A binds and mobilizes ligands IEA Caenorhabditis elegans 90164 R-CEL-9840884 https://reactome.org/PathwayBrowser/#/R-CEL-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Caenorhabditis elegans 90164 R-CFA-1605717 https://reactome.org/PathwayBrowser/#/R-CFA-1605717 GM2A binds and mobilizes ligands IEA Canis familiaris 90164 R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 90164 R-CFA-9840884 https://reactome.org/PathwayBrowser/#/R-CFA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Canis familiaris 90164 R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 90164 R-HSA-1605717 https://reactome.org/PathwayBrowser/#/R-HSA-1605717 GM2A binds and mobilizes ligands TAS Homo sapiens 90164 R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 90164 R-HSA-9840884 https://reactome.org/PathwayBrowser/#/R-HSA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 TAS Homo sapiens 90164 R-MMU-1605717 https://reactome.org/PathwayBrowser/#/R-MMU-1605717 GM2A binds and mobilizes ligands IEA Mus musculus 90164 R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 90164 R-MMU-9840884 https://reactome.org/PathwayBrowser/#/R-MMU-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Mus musculus 90164 R-RNO-1605717 https://reactome.org/PathwayBrowser/#/R-RNO-1605717 GM2A binds and mobilizes ligands IEA Rattus norvegicus 90164 R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 90164 R-RNO-9840884 https://reactome.org/PathwayBrowser/#/R-RNO-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Rattus norvegicus 90164 R-SSC-1605717 https://reactome.org/PathwayBrowser/#/R-SSC-1605717 GM2A binds and mobilizes ligands IEA Sus scrofa 90164 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 90164 R-SSC-9840884 https://reactome.org/PathwayBrowser/#/R-SSC-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Sus scrofa 90164 R-XTR-1605717 https://reactome.org/PathwayBrowser/#/R-XTR-1605717 GM2A binds and mobilizes ligands IEA Xenopus tropicalis 90164 R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 90171 R-BTA-8956458 https://reactome.org/PathwayBrowser/#/R-BTA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Bos taurus 90171 R-CFA-8956458 https://reactome.org/PathwayBrowser/#/R-CFA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Canis familiaris 90171 R-DRE-8956458 https://reactome.org/PathwayBrowser/#/R-DRE-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Danio rerio 90171 R-GGA-8956458 https://reactome.org/PathwayBrowser/#/R-GGA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Gallus gallus 90171 R-HSA-8956458 https://reactome.org/PathwayBrowser/#/R-HSA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ TAS Homo sapiens 90171 R-MMU-8956458 https://reactome.org/PathwayBrowser/#/R-MMU-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Mus musculus 90171 R-RNO-8956458 https://reactome.org/PathwayBrowser/#/R-RNO-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Rattus norvegicus 90171 R-SSC-8956458 https://reactome.org/PathwayBrowser/#/R-SSC-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Sus scrofa 90171 R-XTR-8956458 https://reactome.org/PathwayBrowser/#/R-XTR-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Xenopus tropicalis 90174 R-BTA-8956458 https://reactome.org/PathwayBrowser/#/R-BTA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Bos taurus 90174 R-CFA-8956458 https://reactome.org/PathwayBrowser/#/R-CFA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Canis familiaris 90174 R-DRE-8956458 https://reactome.org/PathwayBrowser/#/R-DRE-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Danio rerio 90174 R-GGA-8956458 https://reactome.org/PathwayBrowser/#/R-GGA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Gallus gallus 90174 R-HSA-8956458 https://reactome.org/PathwayBrowser/#/R-HSA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ TAS Homo sapiens 90174 R-MMU-8956458 https://reactome.org/PathwayBrowser/#/R-MMU-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Mus musculus 90174 R-RNO-8956458 https://reactome.org/PathwayBrowser/#/R-RNO-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Rattus norvegicus 90174 R-SSC-8956458 https://reactome.org/PathwayBrowser/#/R-SSC-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Sus scrofa 90174 R-XTR-8956458 https://reactome.org/PathwayBrowser/#/R-XTR-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Xenopus tropicalis 90176 R-BTA-9749971 https://reactome.org/PathwayBrowser/#/R-BTA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Bos taurus 90176 R-BTA-9750001 https://reactome.org/PathwayBrowser/#/R-BTA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Bos taurus 90176 R-CEL-9750001 https://reactome.org/PathwayBrowser/#/R-CEL-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Caenorhabditis elegans 90176 R-CFA-9749971 https://reactome.org/PathwayBrowser/#/R-CFA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Canis familiaris 90176 R-CFA-9750001 https://reactome.org/PathwayBrowser/#/R-CFA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Canis familiaris 90176 R-DRE-9749971 https://reactome.org/PathwayBrowser/#/R-DRE-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Danio rerio 90176 R-GGA-9749971 https://reactome.org/PathwayBrowser/#/R-GGA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Gallus gallus 90176 R-GGA-9750001 https://reactome.org/PathwayBrowser/#/R-GGA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Gallus gallus 90176 R-HSA-9749971 https://reactome.org/PathwayBrowser/#/R-HSA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA TAS Homo sapiens 90176 R-HSA-9750001 https://reactome.org/PathwayBrowser/#/R-HSA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid TAS Homo sapiens 90176 R-MMU-9749971 https://reactome.org/PathwayBrowser/#/R-MMU-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Mus musculus 90176 R-MMU-9750001 https://reactome.org/PathwayBrowser/#/R-MMU-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Mus musculus 90176 R-RNO-9749971 https://reactome.org/PathwayBrowser/#/R-RNO-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Rattus norvegicus 90176 R-RNO-9750001 https://reactome.org/PathwayBrowser/#/R-RNO-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Rattus norvegicus 90176 R-SSC-9749971 https://reactome.org/PathwayBrowser/#/R-SSC-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Sus scrofa 90176 R-SSC-9750001 https://reactome.org/PathwayBrowser/#/R-SSC-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Sus scrofa 90176 R-XTR-9749971 https://reactome.org/PathwayBrowser/#/R-XTR-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Xenopus tropicalis 90176 R-XTR-9750001 https://reactome.org/PathwayBrowser/#/R-XTR-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Xenopus tropicalis 90189 R-BTA-9846332 https://reactome.org/PathwayBrowser/#/R-BTA-9846332 FUT1,2 transfer fucose to gangliosides IEA Bos taurus 90189 R-CEL-9846332 https://reactome.org/PathwayBrowser/#/R-CEL-9846332 FUT1,2 transfer fucose to gangliosides IEA Caenorhabditis elegans 90189 R-CFA-9846332 https://reactome.org/PathwayBrowser/#/R-CFA-9846332 FUT1,2 transfer fucose to gangliosides IEA Canis familiaris 90189 R-HSA-9846332 https://reactome.org/PathwayBrowser/#/R-HSA-9846332 FUT1,2 transfer fucose to gangliosides TAS Homo sapiens 90189 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 90189 R-MMU-9846332 https://reactome.org/PathwayBrowser/#/R-MMU-9846332 FUT1,2 transfer fucose to gangliosides IEA Mus musculus 90189 R-RNO-9846332 https://reactome.org/PathwayBrowser/#/R-RNO-9846332 FUT1,2 transfer fucose to gangliosides IEA Rattus norvegicus 90189 R-SSC-9846332 https://reactome.org/PathwayBrowser/#/R-SSC-9846332 FUT1,2 transfer fucose to gangliosides IEA Sus scrofa 90189 R-XTR-9846332 https://reactome.org/PathwayBrowser/#/R-XTR-9846332 FUT1,2 transfer fucose to gangliosides IEA Xenopus tropicalis 90227 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 90227 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 90227 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 90227 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 90227 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 90227 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 90227 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 90227 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 90227 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 90227 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 90227 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 90227 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 90227 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 90227 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 90227 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 90227 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 90227 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 90227 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 90262 R-BTA-9846332 https://reactome.org/PathwayBrowser/#/R-BTA-9846332 FUT1,2 transfer fucose to gangliosides IEA Bos taurus 90262 R-CEL-9846332 https://reactome.org/PathwayBrowser/#/R-CEL-9846332 FUT1,2 transfer fucose to gangliosides IEA Caenorhabditis elegans 90262 R-CFA-9846332 https://reactome.org/PathwayBrowser/#/R-CFA-9846332 FUT1,2 transfer fucose to gangliosides IEA Canis familiaris 90262 R-HSA-9846332 https://reactome.org/PathwayBrowser/#/R-HSA-9846332 FUT1,2 transfer fucose to gangliosides TAS Homo sapiens 90262 R-HSA-9850731 https://reactome.org/PathwayBrowser/#/R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane TAS Homo sapiens 90262 R-MMU-9846332 https://reactome.org/PathwayBrowser/#/R-MMU-9846332 FUT1,2 transfer fucose to gangliosides IEA Mus musculus 90262 R-RNO-9846332 https://reactome.org/PathwayBrowser/#/R-RNO-9846332 FUT1,2 transfer fucose to gangliosides IEA Rattus norvegicus 90262 R-SSC-9846332 https://reactome.org/PathwayBrowser/#/R-SSC-9846332 FUT1,2 transfer fucose to gangliosides IEA Sus scrofa 90262 R-XTR-9846332 https://reactome.org/PathwayBrowser/#/R-XTR-9846332 FUT1,2 transfer fucose to gangliosides IEA Xenopus tropicalis 90295 R-HSA-6802918 https://reactome.org/PathwayBrowser/#/R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants TAS Homo sapiens 90295 R-HSA-6802937 https://reactome.org/PathwayBrowser/#/R-HSA-6802937 Inactive BRAF mutants bind mutant RAS:GTP TAS Homo sapiens 90295 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 90295 R-HSA-6802941 https://reactome.org/PathwayBrowser/#/R-HSA-6802941 RAF is paradoxically phosphorylated downstream of kinase-inactive RAF TAS Homo sapiens 90295 R-HSA-6802942 https://reactome.org/PathwayBrowser/#/R-HSA-6802942 RAS:GTP:p-RAF complexes paradoxically bind MAP2Ks and MAPKs TAS Homo sapiens 90295 R-HSA-6802943 https://reactome.org/PathwayBrowser/#/R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 90295 R-HSA-6803234 https://reactome.org/PathwayBrowser/#/R-HSA-6803234 Dissociation of paradoxically activated RAS:BRAF complexes TAS Homo sapiens 90295 R-HSA-8936731 https://reactome.org/PathwayBrowser/#/R-HSA-8936731 Inactive BRAF mutants:mutant RAS:GTP bind RAF1 TAS Homo sapiens 90596 R-BTA-5676966 https://reactome.org/PathwayBrowser/#/R-BTA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Bos taurus 90596 R-CEL-5676966 https://reactome.org/PathwayBrowser/#/R-CEL-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Caenorhabditis elegans 90596 R-CFA-5676966 https://reactome.org/PathwayBrowser/#/R-CFA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Canis familiaris 90596 R-DDI-5676966 https://reactome.org/PathwayBrowser/#/R-DDI-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Dictyostelium discoideum 90596 R-DME-5676966 https://reactome.org/PathwayBrowser/#/R-DME-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Drosophila melanogaster 90596 R-DRE-5676966 https://reactome.org/PathwayBrowser/#/R-DRE-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Danio rerio 90596 R-GGA-5676966 https://reactome.org/PathwayBrowser/#/R-GGA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Gallus gallus 90596 R-HSA-5676966 https://reactome.org/PathwayBrowser/#/R-HSA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp TAS Homo sapiens 90596 R-HSA-5685345 https://reactome.org/PathwayBrowser/#/R-HSA-5685345 Formation of isoAsp TAS Homo sapiens 90596 R-HSA-5687520 https://reactome.org/PathwayBrowser/#/R-HSA-5687520 MetAsp transforms to L-Asp,isoAsp TAS Homo sapiens 90596 R-MMU-5676966 https://reactome.org/PathwayBrowser/#/R-MMU-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Mus musculus 90596 R-PFA-5676966 https://reactome.org/PathwayBrowser/#/R-PFA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Plasmodium falciparum 90596 R-RNO-5676966 https://reactome.org/PathwayBrowser/#/R-RNO-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Rattus norvegicus 90596 R-SPO-5676966 https://reactome.org/PathwayBrowser/#/R-SPO-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Schizosaccharomyces pombe 90596 R-SSC-5676966 https://reactome.org/PathwayBrowser/#/R-SSC-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Sus scrofa 9066 R-BTA-2408551 https://reactome.org/PathwayBrowser/#/R-BTA-2408551 SeMet is converted to AdoSeMet by MAT IEA Bos taurus 9066 R-CFA-2408551 https://reactome.org/PathwayBrowser/#/R-CFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Canis familiaris 9066 R-DDI-2408551 https://reactome.org/PathwayBrowser/#/R-DDI-2408551 SeMet is converted to AdoSeMet by MAT IEA Dictyostelium discoideum 9066 R-DRE-2408551 https://reactome.org/PathwayBrowser/#/R-DRE-2408551 SeMet is converted to AdoSeMet by MAT IEA Danio rerio 9066 R-GGA-2408551 https://reactome.org/PathwayBrowser/#/R-GGA-2408551 SeMet is converted to AdoSeMet by MAT IEA Gallus gallus 9066 R-HSA-2408544 https://reactome.org/PathwayBrowser/#/R-HSA-2408544 AdoSeMet is converted to AdeSeHCys by MetTrans(1) IEA Homo sapiens 9066 R-HSA-2408551 https://reactome.org/PathwayBrowser/#/R-HSA-2408551 SeMet is converted to AdoSeMet by MAT TAS Homo sapiens 9066 R-MMU-2408551 https://reactome.org/PathwayBrowser/#/R-MMU-2408551 SeMet is converted to AdoSeMet by MAT IEA Mus musculus 9066 R-PFA-2408551 https://reactome.org/PathwayBrowser/#/R-PFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Plasmodium falciparum 9066 R-RNO-2408545 https://reactome.org/PathwayBrowser/#/R-RNO-2408545 AdoSeMet is converted to AdeSeHCys by MetTrans(2) TAS Rattus norvegicus 9066 R-RNO-2408551 https://reactome.org/PathwayBrowser/#/R-RNO-2408551 SeMet is converted to AdoSeMet by MAT IEA Rattus norvegicus 9066 R-SCE-2408551 https://reactome.org/PathwayBrowser/#/R-SCE-2408551 SeMet is converted to AdoSeMet by MAT IEA Saccharomyces cerevisiae 9066 R-SPO-2408551 https://reactome.org/PathwayBrowser/#/R-SPO-2408551 SeMet is converted to AdoSeMet by MAT IEA Schizosaccharomyces pombe 9066 R-SSC-2408551 https://reactome.org/PathwayBrowser/#/R-SSC-2408551 SeMet is converted to AdoSeMet by MAT IEA Sus scrofa 9066 R-XTR-2408551 https://reactome.org/PathwayBrowser/#/R-XTR-2408551 SeMet is converted to AdoSeMet by MAT IEA Xenopus tropicalis 90779 R-BTA-3095889 https://reactome.org/PathwayBrowser/#/R-BTA-3095889 MMACHC dealkylates RCbl IEA Bos taurus 90779 R-CEL-3095889 https://reactome.org/PathwayBrowser/#/R-CEL-3095889 MMACHC dealkylates RCbl IEA Caenorhabditis elegans 90779 R-CFA-3095889 https://reactome.org/PathwayBrowser/#/R-CFA-3095889 MMACHC dealkylates RCbl IEA Canis familiaris 90779 R-DDI-3095889 https://reactome.org/PathwayBrowser/#/R-DDI-3095889 MMACHC dealkylates RCbl IEA Dictyostelium discoideum 90779 R-DRE-3095889 https://reactome.org/PathwayBrowser/#/R-DRE-3095889 MMACHC dealkylates RCbl IEA Danio rerio 90779 R-GGA-3095889 https://reactome.org/PathwayBrowser/#/R-GGA-3095889 MMACHC dealkylates RCbl IEA Gallus gallus 90779 R-HSA-3095889 https://reactome.org/PathwayBrowser/#/R-HSA-3095889 MMACHC dealkylates RCbl TAS Homo sapiens 90779 R-MMU-3095889 https://reactome.org/PathwayBrowser/#/R-MMU-3095889 MMACHC dealkylates RCbl IEA Mus musculus 90779 R-RNO-3095889 https://reactome.org/PathwayBrowser/#/R-RNO-3095889 MMACHC dealkylates RCbl IEA Rattus norvegicus 90779 R-SSC-3095889 https://reactome.org/PathwayBrowser/#/R-SSC-3095889 MMACHC dealkylates RCbl IEA Sus scrofa 90779 R-XTR-3095889 https://reactome.org/PathwayBrowser/#/R-XTR-3095889 MMACHC dealkylates RCbl IEA Xenopus tropicalis 90799 R-BTA-427998 https://reactome.org/PathwayBrowser/#/R-BTA-427998 Proton-coupled di- and tri-peptide cotransport IEA Bos taurus 90799 R-BTA-428007 https://reactome.org/PathwayBrowser/#/R-BTA-428007 Proton-coupled histidine and di-peptide cotransport IEA Bos taurus 90799 R-CEL-427998 https://reactome.org/PathwayBrowser/#/R-CEL-427998 Proton-coupled di- and tri-peptide cotransport IEA Caenorhabditis elegans 90799 R-CFA-427998 https://reactome.org/PathwayBrowser/#/R-CFA-427998 Proton-coupled di- and tri-peptide cotransport IEA Canis familiaris 90799 R-CFA-428007 https://reactome.org/PathwayBrowser/#/R-CFA-428007 Proton-coupled histidine and di-peptide cotransport IEA Canis familiaris 90799 R-DDI-427998 https://reactome.org/PathwayBrowser/#/R-DDI-427998 Proton-coupled di- and tri-peptide cotransport IEA Dictyostelium discoideum 90799 R-DME-427998 https://reactome.org/PathwayBrowser/#/R-DME-427998 Proton-coupled di- and tri-peptide cotransport IEA Drosophila melanogaster 90799 R-DRE-427998 https://reactome.org/PathwayBrowser/#/R-DRE-427998 Proton-coupled di- and tri-peptide cotransport IEA Danio rerio 90799 R-GGA-427998 https://reactome.org/PathwayBrowser/#/R-GGA-427998 Proton-coupled di- and tri-peptide cotransport IEA Gallus gallus 90799 R-GGA-428007 https://reactome.org/PathwayBrowser/#/R-GGA-428007 Proton-coupled histidine and di-peptide cotransport IEA Gallus gallus 90799 R-HSA-427998 https://reactome.org/PathwayBrowser/#/R-HSA-427998 Proton-coupled di- and tri-peptide cotransport TAS Homo sapiens 90799 R-HSA-428007 https://reactome.org/PathwayBrowser/#/R-HSA-428007 Proton-coupled histidine and di-peptide cotransport TAS Homo sapiens 90799 R-MMU-427998 https://reactome.org/PathwayBrowser/#/R-MMU-427998 Proton-coupled di- and tri-peptide cotransport IEA Mus musculus 90799 R-MMU-428007 https://reactome.org/PathwayBrowser/#/R-MMU-428007 Proton-coupled histidine and di-peptide cotransport IEA Mus musculus 90799 R-RNO-427998 https://reactome.org/PathwayBrowser/#/R-RNO-427998 Proton-coupled di- and tri-peptide cotransport IEA Rattus norvegicus 90799 R-RNO-428007 https://reactome.org/PathwayBrowser/#/R-RNO-428007 Proton-coupled histidine and di-peptide cotransport IEA Rattus norvegicus 90799 R-SCE-428007 https://reactome.org/PathwayBrowser/#/R-SCE-428007 Proton-coupled histidine and di-peptide cotransport IEA Saccharomyces cerevisiae 90799 R-SPO-428007 https://reactome.org/PathwayBrowser/#/R-SPO-428007 Proton-coupled histidine and di-peptide cotransport IEA Schizosaccharomyces pombe 90799 R-SSC-427998 https://reactome.org/PathwayBrowser/#/R-SSC-427998 Proton-coupled di- and tri-peptide cotransport IEA Sus scrofa 90799 R-SSC-428007 https://reactome.org/PathwayBrowser/#/R-SSC-428007 Proton-coupled histidine and di-peptide cotransport IEA Sus scrofa 90799 R-XTR-427998 https://reactome.org/PathwayBrowser/#/R-XTR-427998 Proton-coupled di- and tri-peptide cotransport IEA Xenopus tropicalis 90799 R-XTR-428007 https://reactome.org/PathwayBrowser/#/R-XTR-428007 Proton-coupled histidine and di-peptide cotransport IEA Xenopus tropicalis 90815 R-BTA-9027532 https://reactome.org/PathwayBrowser/#/R-BTA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Bos taurus 90815 R-CFA-9027532 https://reactome.org/PathwayBrowser/#/R-CFA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Canis familiaris 90815 R-DRE-9027532 https://reactome.org/PathwayBrowser/#/R-DRE-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Danio rerio 90815 R-GGA-9027532 https://reactome.org/PathwayBrowser/#/R-GGA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Gallus gallus 90815 R-HSA-9027531 https://reactome.org/PathwayBrowser/#/R-HSA-9027531 Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA TAS Homo sapiens 90815 R-HSA-9027532 https://reactome.org/PathwayBrowser/#/R-HSA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA TAS Homo sapiens 90815 R-MMU-9027532 https://reactome.org/PathwayBrowser/#/R-MMU-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Mus musculus 90815 R-RNO-9027532 https://reactome.org/PathwayBrowser/#/R-RNO-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Rattus norvegicus 90815 R-SSC-9027532 https://reactome.org/PathwayBrowser/#/R-SSC-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Sus scrofa 90815 R-XTR-9027532 https://reactome.org/PathwayBrowser/#/R-XTR-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Xenopus tropicalis 90824 R-BTA-9026405 https://reactome.org/PathwayBrowser/#/R-BTA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Bos taurus 90824 R-BTA-9026408 https://reactome.org/PathwayBrowser/#/R-BTA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Bos taurus 90824 R-CFA-9026405 https://reactome.org/PathwayBrowser/#/R-CFA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Canis familiaris 90824 R-CFA-9026408 https://reactome.org/PathwayBrowser/#/R-CFA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Canis familiaris 90824 R-DDI-9026405 https://reactome.org/PathwayBrowser/#/R-DDI-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Dictyostelium discoideum 90824 R-DRE-9026405 https://reactome.org/PathwayBrowser/#/R-DRE-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Danio rerio 90824 R-DRE-9026408 https://reactome.org/PathwayBrowser/#/R-DRE-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Danio rerio 90824 R-GGA-9026405 https://reactome.org/PathwayBrowser/#/R-GGA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Gallus gallus 90824 R-GGA-9026408 https://reactome.org/PathwayBrowser/#/R-GGA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Gallus gallus 90824 R-HSA-9026405 https://reactome.org/PathwayBrowser/#/R-HSA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 TAS Homo sapiens 90824 R-HSA-9026408 https://reactome.org/PathwayBrowser/#/R-HSA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 TAS Homo sapiens 90824 R-HSA-9026411 https://reactome.org/PathwayBrowser/#/R-HSA-9026411 13(R)-HDPAn-3 translocates from endothelial cell to neutrophil TAS Homo sapiens 90824 R-HSA-9027598 https://reactome.org/PathwayBrowser/#/R-HSA-9027598 Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3 TAS Homo sapiens 90824 R-MMU-9026405 https://reactome.org/PathwayBrowser/#/R-MMU-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Mus musculus 90824 R-MMU-9026408 https://reactome.org/PathwayBrowser/#/R-MMU-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Mus musculus 90824 R-RNO-9026405 https://reactome.org/PathwayBrowser/#/R-RNO-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Rattus norvegicus 90824 R-RNO-9026408 https://reactome.org/PathwayBrowser/#/R-RNO-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Rattus norvegicus 90824 R-SSC-9026405 https://reactome.org/PathwayBrowser/#/R-SSC-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Sus scrofa 90824 R-SSC-9026408 https://reactome.org/PathwayBrowser/#/R-SSC-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Sus scrofa 90824 R-XTR-9026405 https://reactome.org/PathwayBrowser/#/R-XTR-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Xenopus tropicalis 90824 R-XTR-9026408 https://reactome.org/PathwayBrowser/#/R-XTR-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Xenopus tropicalis 90832 R-BTA-6809287 https://reactome.org/PathwayBrowser/#/R-BTA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Bos taurus 90832 R-CEL-6809287 https://reactome.org/PathwayBrowser/#/R-CEL-6809287 NUDT12 hydrolyses NADH to NMNH IEA Caenorhabditis elegans 90832 R-CFA-6809287 https://reactome.org/PathwayBrowser/#/R-CFA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Canis familiaris 90832 R-DDI-6809287 https://reactome.org/PathwayBrowser/#/R-DDI-6809287 NUDT12 hydrolyses NADH to NMNH IEA Dictyostelium discoideum 90832 R-DRE-6809287 https://reactome.org/PathwayBrowser/#/R-DRE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Danio rerio 90832 R-GGA-6809287 https://reactome.org/PathwayBrowser/#/R-GGA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Gallus gallus 90832 R-HSA-6809287 https://reactome.org/PathwayBrowser/#/R-HSA-6809287 NUDT12 hydrolyses NADH to NMNH TAS Homo sapiens 90832 R-MMU-6809287 https://reactome.org/PathwayBrowser/#/R-MMU-6809287 NUDT12 hydrolyses NADH to NMNH IEA Mus musculus 90832 R-RNO-6809287 https://reactome.org/PathwayBrowser/#/R-RNO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Rattus norvegicus 90832 R-SCE-6809287 https://reactome.org/PathwayBrowser/#/R-SCE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Saccharomyces cerevisiae 90832 R-SPO-6809287 https://reactome.org/PathwayBrowser/#/R-SPO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Schizosaccharomyces pombe 90832 R-SSC-6809287 https://reactome.org/PathwayBrowser/#/R-SSC-6809287 NUDT12 hydrolyses NADH to NMNH IEA Sus scrofa 90832 R-XTR-6809287 https://reactome.org/PathwayBrowser/#/R-XTR-6809287 NUDT12 hydrolyses NADH to NMNH IEA Xenopus tropicalis 90841 R-BTA-417829 https://reactome.org/PathwayBrowser/#/R-BTA-417829 P2RY12 binds ADP IEA Bos taurus 90841 R-BTA-9611277 https://reactome.org/PathwayBrowser/#/R-BTA-9611277 P2RY12 binds P2RY12 antagonists IEA Bos taurus 90841 R-CFA-417829 https://reactome.org/PathwayBrowser/#/R-CFA-417829 P2RY12 binds ADP IEA Canis familiaris 90841 R-CFA-9611277 https://reactome.org/PathwayBrowser/#/R-CFA-9611277 P2RY12 binds P2RY12 antagonists IEA Canis familiaris 90841 R-DRE-417829 https://reactome.org/PathwayBrowser/#/R-DRE-417829 P2RY12 binds ADP IEA Danio rerio 90841 R-DRE-9611277 https://reactome.org/PathwayBrowser/#/R-DRE-9611277 P2RY12 binds P2RY12 antagonists IEA Danio rerio 90841 R-HSA-417829 https://reactome.org/PathwayBrowser/#/R-HSA-417829 P2RY12 binds ADP TAS Homo sapiens 90841 R-HSA-9611277 https://reactome.org/PathwayBrowser/#/R-HSA-9611277 P2RY12 binds P2RY12 antagonists TAS Homo sapiens 90841 R-MMU-417829 https://reactome.org/PathwayBrowser/#/R-MMU-417829 P2RY12 binds ADP IEA Mus musculus 90841 R-MMU-9611277 https://reactome.org/PathwayBrowser/#/R-MMU-9611277 P2RY12 binds P2RY12 antagonists IEA Mus musculus 90841 R-RNO-417829 https://reactome.org/PathwayBrowser/#/R-RNO-417829 P2RY12 binds ADP IEA Rattus norvegicus 90841 R-RNO-9611277 https://reactome.org/PathwayBrowser/#/R-RNO-9611277 P2RY12 binds P2RY12 antagonists IEA Rattus norvegicus 90841 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa 90841 R-SSC-9611277 https://reactome.org/PathwayBrowser/#/R-SSC-9611277 P2RY12 binds P2RY12 antagonists IEA Sus scrofa 90841 R-XTR-417829 https://reactome.org/PathwayBrowser/#/R-XTR-417829 P2RY12 binds ADP IEA Xenopus tropicalis 90841 R-XTR-9611277 https://reactome.org/PathwayBrowser/#/R-XTR-9611277 P2RY12 binds P2RY12 antagonists IEA Xenopus tropicalis 90851 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 90851 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 90851 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 90851 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 90851 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 90851 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 90851 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 90851 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 90851 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 90851 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 90851 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 90851 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 90851 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 90851 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 90851 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 90851 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 90851 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 90851 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 90933 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 90933 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 90933 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 90933 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 90933 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 90933 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 90933 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 90933 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 90933 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 90933 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 90943 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 90943 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 90943 R-HSA-9665280 https://reactome.org/PathwayBrowser/#/R-HSA-9665280 ERBB2 KD mutants do not bind osimertinib TAS Homo sapiens 9096 R-HSA-2408532 https://reactome.org/PathwayBrowser/#/R-HSA-2408532 AdeSeHCys is hydrolysed to SeHCys by AHCY IEA Homo sapiens 9096 R-HSA-2408559 https://reactome.org/PathwayBrowser/#/R-HSA-2408559 SeHCys and Ser are dehydrated into SeCysta by CBS IEA Homo sapiens 9096 R-RNO-2408512 https://reactome.org/PathwayBrowser/#/R-RNO-2408512 AdeSeHCys is hydrolysed to SeHCys by Ahcy TAS Rattus norvegicus 9096 R-RNO-2408533 https://reactome.org/PathwayBrowser/#/R-RNO-2408533 SeHCys and Ser are dehydrated into SeCysta by Cbs TAS Rattus norvegicus 9100 R-HSA-2408546 https://reactome.org/PathwayBrowser/#/R-HSA-2408546 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex IEA Homo sapiens 9100 R-TAE-2408513 https://reactome.org/PathwayBrowser/#/R-TAE-2408513 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Triticum aestivum 9100 R-VRA-2408510 https://reactome.org/PathwayBrowser/#/R-VRA-2408510 tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars TAS Vigna radiata var. radiata 91091 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 91091 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 91091 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 91107 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 91107 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 91107 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 91124 R-BTA-5617143 https://reactome.org/PathwayBrowser/#/R-BTA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Bos taurus 91124 R-BTA-9638097 https://reactome.org/PathwayBrowser/#/R-BTA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Bos taurus 91124 R-CFA-5617143 https://reactome.org/PathwayBrowser/#/R-CFA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Canis familiaris 91124 R-CFA-9638097 https://reactome.org/PathwayBrowser/#/R-CFA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Canis familiaris 91124 R-DRE-5617143 https://reactome.org/PathwayBrowser/#/R-DRE-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Danio rerio 91124 R-DRE-9638097 https://reactome.org/PathwayBrowser/#/R-DRE-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Danio rerio 91124 R-HSA-5617143 https://reactome.org/PathwayBrowser/#/R-HSA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA TAS Homo sapiens 91124 R-HSA-9638097 https://reactome.org/PathwayBrowser/#/R-HSA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA TAS Homo sapiens 91124 R-MMU-5617143 https://reactome.org/PathwayBrowser/#/R-MMU-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Mus musculus 91124 R-MMU-9638097 https://reactome.org/PathwayBrowser/#/R-MMU-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Mus musculus 91124 R-RNO-5617143 https://reactome.org/PathwayBrowser/#/R-RNO-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Rattus norvegicus 91124 R-RNO-9638097 https://reactome.org/PathwayBrowser/#/R-RNO-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Rattus norvegicus 91124 R-SSC-5617143 https://reactome.org/PathwayBrowser/#/R-SSC-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Sus scrofa 91124 R-SSC-9638097 https://reactome.org/PathwayBrowser/#/R-SSC-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Sus scrofa 91124 R-XTR-5617143 https://reactome.org/PathwayBrowser/#/R-XTR-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Xenopus tropicalis 91124 R-XTR-9638097 https://reactome.org/PathwayBrowser/#/R-XTR-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Xenopus tropicalis 91125 R-BTA-5617138 https://reactome.org/PathwayBrowser/#/R-BTA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Bos taurus 91125 R-BTA-5617143 https://reactome.org/PathwayBrowser/#/R-BTA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Bos taurus 91125 R-BTA-9638090 https://reactome.org/PathwayBrowser/#/R-BTA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Bos taurus 91125 R-BTA-9638097 https://reactome.org/PathwayBrowser/#/R-BTA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Bos taurus 91125 R-CFA-5617138 https://reactome.org/PathwayBrowser/#/R-CFA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Canis familiaris 91125 R-CFA-5617143 https://reactome.org/PathwayBrowser/#/R-CFA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Canis familiaris 91125 R-CFA-9638090 https://reactome.org/PathwayBrowser/#/R-CFA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Canis familiaris 91125 R-CFA-9638097 https://reactome.org/PathwayBrowser/#/R-CFA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Canis familiaris 91125 R-DRE-5617138 https://reactome.org/PathwayBrowser/#/R-DRE-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Danio rerio 91125 R-DRE-5617143 https://reactome.org/PathwayBrowser/#/R-DRE-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Danio rerio 91125 R-DRE-9638090 https://reactome.org/PathwayBrowser/#/R-DRE-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Danio rerio 91125 R-DRE-9638097 https://reactome.org/PathwayBrowser/#/R-DRE-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Danio rerio 91125 R-HSA-5617138 https://reactome.org/PathwayBrowser/#/R-HSA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA TAS Homo sapiens 91125 R-HSA-5617143 https://reactome.org/PathwayBrowser/#/R-HSA-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA TAS Homo sapiens 91125 R-HSA-9638090 https://reactome.org/PathwayBrowser/#/R-HSA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA TAS Homo sapiens 91125 R-HSA-9638097 https://reactome.org/PathwayBrowser/#/R-HSA-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA TAS Homo sapiens 91125 R-MMU-5617138 https://reactome.org/PathwayBrowser/#/R-MMU-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Mus musculus 91125 R-MMU-5617143 https://reactome.org/PathwayBrowser/#/R-MMU-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Mus musculus 91125 R-MMU-9638090 https://reactome.org/PathwayBrowser/#/R-MMU-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Mus musculus 91125 R-MMU-9638097 https://reactome.org/PathwayBrowser/#/R-MMU-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Mus musculus 91125 R-RNO-5617138 https://reactome.org/PathwayBrowser/#/R-RNO-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Rattus norvegicus 91125 R-RNO-5617143 https://reactome.org/PathwayBrowser/#/R-RNO-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Rattus norvegicus 91125 R-RNO-9638090 https://reactome.org/PathwayBrowser/#/R-RNO-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Rattus norvegicus 91125 R-RNO-9638097 https://reactome.org/PathwayBrowser/#/R-RNO-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Rattus norvegicus 91125 R-SSC-5617138 https://reactome.org/PathwayBrowser/#/R-SSC-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Sus scrofa 91125 R-SSC-5617143 https://reactome.org/PathwayBrowser/#/R-SSC-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Sus scrofa 91125 R-SSC-9638090 https://reactome.org/PathwayBrowser/#/R-SSC-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Sus scrofa 91125 R-SSC-9638097 https://reactome.org/PathwayBrowser/#/R-SSC-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Sus scrofa 91125 R-XTR-5617138 https://reactome.org/PathwayBrowser/#/R-XTR-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Xenopus tropicalis 91125 R-XTR-5617143 https://reactome.org/PathwayBrowser/#/R-XTR-5617143 B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Xenopus tropicalis 91125 R-XTR-9638090 https://reactome.org/PathwayBrowser/#/R-XTR-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Xenopus tropicalis 91125 R-XTR-9638097 https://reactome.org/PathwayBrowser/#/R-XTR-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Xenopus tropicalis 91137 R-BTA-9020251 https://reactome.org/PathwayBrowser/#/R-BTA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Bos taurus 91137 R-BTA-9020259 https://reactome.org/PathwayBrowser/#/R-BTA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Bos taurus 91137 R-BTA-9020271 https://reactome.org/PathwayBrowser/#/R-BTA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Bos taurus 91137 R-CEL-9020271 https://reactome.org/PathwayBrowser/#/R-CEL-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Caenorhabditis elegans 91137 R-CFA-9020251 https://reactome.org/PathwayBrowser/#/R-CFA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Canis familiaris 91137 R-CFA-9020259 https://reactome.org/PathwayBrowser/#/R-CFA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Canis familiaris 91137 R-CFA-9020271 https://reactome.org/PathwayBrowser/#/R-CFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Canis familiaris 91137 R-DDI-9020251 https://reactome.org/PathwayBrowser/#/R-DDI-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Dictyostelium discoideum 91137 R-DDI-9020259 https://reactome.org/PathwayBrowser/#/R-DDI-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Dictyostelium discoideum 91137 R-DRE-9020251 https://reactome.org/PathwayBrowser/#/R-DRE-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Danio rerio 91137 R-DRE-9020259 https://reactome.org/PathwayBrowser/#/R-DRE-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Danio rerio 91137 R-GGA-9020251 https://reactome.org/PathwayBrowser/#/R-GGA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Gallus gallus 91137 R-GGA-9020259 https://reactome.org/PathwayBrowser/#/R-GGA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Gallus gallus 91137 R-GGA-9020271 https://reactome.org/PathwayBrowser/#/R-GGA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Gallus gallus 91137 R-HSA-9020251 https://reactome.org/PathwayBrowser/#/R-HSA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA TAS Homo sapiens 91137 R-HSA-9020259 https://reactome.org/PathwayBrowser/#/R-HSA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA TAS Homo sapiens 91137 R-HSA-9020271 https://reactome.org/PathwayBrowser/#/R-HSA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA TAS Homo sapiens 91137 R-MMU-9020251 https://reactome.org/PathwayBrowser/#/R-MMU-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Mus musculus 91137 R-MMU-9020259 https://reactome.org/PathwayBrowser/#/R-MMU-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Mus musculus 91137 R-MMU-9020271 https://reactome.org/PathwayBrowser/#/R-MMU-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Mus musculus 91137 R-PFA-9020271 https://reactome.org/PathwayBrowser/#/R-PFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Plasmodium falciparum 91137 R-RNO-9020251 https://reactome.org/PathwayBrowser/#/R-RNO-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Rattus norvegicus 91137 R-RNO-9020259 https://reactome.org/PathwayBrowser/#/R-RNO-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Rattus norvegicus 91137 R-RNO-9020271 https://reactome.org/PathwayBrowser/#/R-RNO-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Rattus norvegicus 91137 R-SSC-9020251 https://reactome.org/PathwayBrowser/#/R-SSC-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Sus scrofa 91137 R-SSC-9020259 https://reactome.org/PathwayBrowser/#/R-SSC-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Sus scrofa 91137 R-SSC-9020271 https://reactome.org/PathwayBrowser/#/R-SSC-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Sus scrofa 91137 R-XTR-9020251 https://reactome.org/PathwayBrowser/#/R-XTR-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Xenopus tropicalis 91137 R-XTR-9020259 https://reactome.org/PathwayBrowser/#/R-XTR-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Xenopus tropicalis 91144 R-BTA-8869206 https://reactome.org/PathwayBrowser/#/R-BTA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Bos taurus 91144 R-CEL-8869206 https://reactome.org/PathwayBrowser/#/R-CEL-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Caenorhabditis elegans 91144 R-CFA-8869206 https://reactome.org/PathwayBrowser/#/R-CFA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Canis familiaris 91144 R-GGA-8869206 https://reactome.org/PathwayBrowser/#/R-GGA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Gallus gallus 91144 R-HSA-8869206 https://reactome.org/PathwayBrowser/#/R-HSA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate TAS Homo sapiens 91144 R-MMU-8869206 https://reactome.org/PathwayBrowser/#/R-MMU-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Mus musculus 91144 R-RNO-8869206 https://reactome.org/PathwayBrowser/#/R-RNO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Rattus norvegicus 91144 R-SPO-8869206 https://reactome.org/PathwayBrowser/#/R-SPO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Schizosaccharomyces pombe 91144 R-SSC-8869206 https://reactome.org/PathwayBrowser/#/R-SSC-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Sus scrofa 91144 R-XTR-8869206 https://reactome.org/PathwayBrowser/#/R-XTR-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Xenopus tropicalis 91279 R-BTA-6799581 https://reactome.org/PathwayBrowser/#/R-BTA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Bos taurus 91279 R-BTA-8853686 https://reactome.org/PathwayBrowser/#/R-BTA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Bos taurus 91279 R-CEL-6799581 https://reactome.org/PathwayBrowser/#/R-CEL-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Caenorhabditis elegans 91279 R-CEL-8853686 https://reactome.org/PathwayBrowser/#/R-CEL-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Caenorhabditis elegans 91279 R-CFA-8853686 https://reactome.org/PathwayBrowser/#/R-CFA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Canis familiaris 91279 R-DDI-6799581 https://reactome.org/PathwayBrowser/#/R-DDI-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Dictyostelium discoideum 91279 R-DDI-8853686 https://reactome.org/PathwayBrowser/#/R-DDI-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Dictyostelium discoideum 91279 R-DME-6799581 https://reactome.org/PathwayBrowser/#/R-DME-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Drosophila melanogaster 91279 R-DME-8853686 https://reactome.org/PathwayBrowser/#/R-DME-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Drosophila melanogaster 91279 R-GGA-6799581 https://reactome.org/PathwayBrowser/#/R-GGA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Gallus gallus 91279 R-HSA-6799581 https://reactome.org/PathwayBrowser/#/R-HSA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man TAS Homo sapiens 91279 R-HSA-8853686 https://reactome.org/PathwayBrowser/#/R-HSA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 TAS Homo sapiens 91279 R-MMU-6799581 https://reactome.org/PathwayBrowser/#/R-MMU-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Mus musculus 91279 R-MMU-8853686 https://reactome.org/PathwayBrowser/#/R-MMU-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Mus musculus 91279 R-RNO-6799581 https://reactome.org/PathwayBrowser/#/R-RNO-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Rattus norvegicus 91279 R-RNO-8853686 https://reactome.org/PathwayBrowser/#/R-RNO-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Rattus norvegicus 91279 R-SSC-6799581 https://reactome.org/PathwayBrowser/#/R-SSC-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Sus scrofa 91279 R-SSC-8853686 https://reactome.org/PathwayBrowser/#/R-SSC-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Sus scrofa 91279 R-XTR-6799581 https://reactome.org/PathwayBrowser/#/R-XTR-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Xenopus tropicalis 91279 R-XTR-8853686 https://reactome.org/PathwayBrowser/#/R-XTR-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Xenopus tropicalis 91280 R-BTA-6799545 https://reactome.org/PathwayBrowser/#/R-BTA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Bos taurus 91280 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 91280 R-BTA-8853686 https://reactome.org/PathwayBrowser/#/R-BTA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Bos taurus 91280 R-CEL-8853686 https://reactome.org/PathwayBrowser/#/R-CEL-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Caenorhabditis elegans 91280 R-CFA-6799545 https://reactome.org/PathwayBrowser/#/R-CFA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Canis familiaris 91280 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 91280 R-CFA-8853686 https://reactome.org/PathwayBrowser/#/R-CFA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Canis familiaris 91280 R-DDI-6799545 https://reactome.org/PathwayBrowser/#/R-DDI-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Dictyostelium discoideum 91280 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 91280 R-DDI-8853686 https://reactome.org/PathwayBrowser/#/R-DDI-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Dictyostelium discoideum 91280 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 91280 R-DME-8853686 https://reactome.org/PathwayBrowser/#/R-DME-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Drosophila melanogaster 91280 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 91280 R-GGA-6799545 https://reactome.org/PathwayBrowser/#/R-GGA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Gallus gallus 91280 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 91280 R-HSA-6799545 https://reactome.org/PathwayBrowser/#/R-HSA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 TAS Homo sapiens 91280 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 91280 R-HSA-8853391 https://reactome.org/PathwayBrowser/#/R-HSA-8853391 GlcNAc (Man)5 translocates from cytosol to lysosomal lumen TAS Homo sapiens 91280 R-HSA-8853686 https://reactome.org/PathwayBrowser/#/R-HSA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 TAS Homo sapiens 91280 R-MMU-6799545 https://reactome.org/PathwayBrowser/#/R-MMU-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Mus musculus 91280 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 91280 R-MMU-8853686 https://reactome.org/PathwayBrowser/#/R-MMU-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Mus musculus 91280 R-RNO-6799545 https://reactome.org/PathwayBrowser/#/R-RNO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Rattus norvegicus 91280 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 91280 R-RNO-8853686 https://reactome.org/PathwayBrowser/#/R-RNO-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Rattus norvegicus 91280 R-SCE-6799545 https://reactome.org/PathwayBrowser/#/R-SCE-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Saccharomyces cerevisiae 91280 R-SPO-6799545 https://reactome.org/PathwayBrowser/#/R-SPO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Schizosaccharomyces pombe 91280 R-SSC-6799545 https://reactome.org/PathwayBrowser/#/R-SSC-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Sus scrofa 91280 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 91280 R-SSC-8853686 https://reactome.org/PathwayBrowser/#/R-SSC-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Sus scrofa 91280 R-XTR-6799545 https://reactome.org/PathwayBrowser/#/R-XTR-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Xenopus tropicalis 91280 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 91280 R-XTR-8853686 https://reactome.org/PathwayBrowser/#/R-XTR-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Xenopus tropicalis 91281 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 91281 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 91281 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 91281 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 91281 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 91281 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 91281 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 91281 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 91281 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 91281 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 91281 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 91282 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 91282 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 91282 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 91282 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 91282 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 91282 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 91282 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 91282 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 91282 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 91282 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 91282 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 91283 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 91283 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 91283 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 91283 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 91283 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 91283 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 91283 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 91283 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 91283 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 91283 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 91283 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 91284 R-BTA-6799545 https://reactome.org/PathwayBrowser/#/R-BTA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Bos taurus 91284 R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 91284 R-CFA-6799545 https://reactome.org/PathwayBrowser/#/R-CFA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Canis familiaris 91284 R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 91284 R-DDI-6799545 https://reactome.org/PathwayBrowser/#/R-DDI-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Dictyostelium discoideum 91284 R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 91284 R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 91284 R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 91284 R-GGA-6799545 https://reactome.org/PathwayBrowser/#/R-GGA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Gallus gallus 91284 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 91284 R-HSA-6799545 https://reactome.org/PathwayBrowser/#/R-HSA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 TAS Homo sapiens 91284 R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 91284 R-MMU-6799545 https://reactome.org/PathwayBrowser/#/R-MMU-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Mus musculus 91284 R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 91284 R-RNO-6799545 https://reactome.org/PathwayBrowser/#/R-RNO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Rattus norvegicus 91284 R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 91284 R-SCE-6799545 https://reactome.org/PathwayBrowser/#/R-SCE-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Saccharomyces cerevisiae 91284 R-SPO-6799545 https://reactome.org/PathwayBrowser/#/R-SPO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Schizosaccharomyces pombe 91284 R-SSC-6799545 https://reactome.org/PathwayBrowser/#/R-SSC-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Sus scrofa 91284 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 91284 R-XTR-6799545 https://reactome.org/PathwayBrowser/#/R-XTR-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Xenopus tropicalis 91284 R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 91338 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 91338 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 91338 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 91338 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 91338 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 91338 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 91338 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 91338 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 91338 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 91338 R-HSA-9700114 https://reactome.org/PathwayBrowser/#/R-HSA-9700114 NVP-TAE684-resistant ALK mutants don't bind NVP-TAE684 TAS Homo sapiens 91338 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 91338 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 91338 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 91338 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 91338 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 91338 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 91338 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 91338 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 91342 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 91342 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 91342 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 91353 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 91353 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 91353 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 91353 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 91353 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 91353 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 91353 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 91353 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 91353 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 91353 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 91353 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 91353 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 91353 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 91353 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 91353 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 91353 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 91353 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 91353 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 91384 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 91384 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 91384 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 91421 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 91421 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 91421 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 91441 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 91441 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 91441 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 91441 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 91441 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 91441 R-HSA-9702570 https://reactome.org/PathwayBrowser/#/R-HSA-9702570 KW2449-resistant FLT3 mutants don't bind KW2449 TAS Homo sapiens 91441 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 91441 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 9160 R-BTA-983218 https://reactome.org/PathwayBrowser/#/R-BTA-983218 RAD51B:RAD51C binds single-stranded DNA IEA Bos taurus 9160 R-CFA-983218 https://reactome.org/PathwayBrowser/#/R-CFA-983218 RAD51B:RAD51C binds single-stranded DNA IEA Canis familiaris 9160 R-DRE-983218 https://reactome.org/PathwayBrowser/#/R-DRE-983218 RAD51B:RAD51C binds single-stranded DNA IEA Danio rerio 9160 R-GGA-983218 https://reactome.org/PathwayBrowser/#/R-GGA-983218 RAD51B:RAD51C binds single-stranded DNA IEA Gallus gallus 9160 R-HSA-9023943 https://reactome.org/PathwayBrowser/#/R-HSA-9023943 MRN:CtIP exonucleolytically hydrolyzes DNA 3' to SPO11 and SPO11:double-strand break dissociates to SPO11:oligonucleotide and resected 5' end IEA Homo sapiens 9160 R-HSA-983218 https://reactome.org/PathwayBrowser/#/R-HSA-983218 RAD51B:RAD51C binds single-stranded DNA TAS Homo sapiens 9160 R-MMU-912357 https://reactome.org/PathwayBrowser/#/R-MMU-912357 Removal of Spo11 and Resection of 5' Ends of DNA TAS Mus musculus 9160 R-MMU-983218 https://reactome.org/PathwayBrowser/#/R-MMU-983218 RAD51B:RAD51C binds single-stranded DNA IEA Mus musculus 9160 R-RNO-983218 https://reactome.org/PathwayBrowser/#/R-RNO-983218 RAD51B:RAD51C binds single-stranded DNA IEA Rattus norvegicus 9160 R-SCE-981784 https://reactome.org/PathwayBrowser/#/R-SCE-981784 Removal of SPO11 and Resection of 5' Ends of DNA (yeast) TAS Saccharomyces cerevisiae 9160 R-SSC-983218 https://reactome.org/PathwayBrowser/#/R-SSC-983218 RAD51B:RAD51C binds single-stranded DNA IEA Sus scrofa 9162 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 9162 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 9162 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 9162 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 9162 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 9162 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 9162 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 9162 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 9162 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 9162 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 9162 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 9162 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 9162 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 9162 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 9162 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 9162 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 9162 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 9162 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 9162 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 9162 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 9162 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 9162 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 9162 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 9162 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 9162 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 9162 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 9162 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 9162 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 9162 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 9162 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 9162 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 9162 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 9162 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 9162 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 9162 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 9162 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 9162 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 9162 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 9162 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 9162 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 9162 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 9162 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 9171 R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 9171 R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 9171 R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 9171 R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 9171 R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 9171 R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 9171 R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 9171 R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 9171 R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 9171 R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa 9171 R-XTR-212005 https://reactome.org/PathwayBrowser/#/R-XTR-212005 CYP2F1 dehydrogenates 3-methylindole IEA Xenopus tropicalis 9254 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 9254 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 9254 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 9254 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 9254 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 9254 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 9254 R-BTA-879585 https://reactome.org/PathwayBrowser/#/R-BTA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Bos taurus 9254 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 9254 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 9254 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 9254 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 9254 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 9254 R-CEL-879585 https://reactome.org/PathwayBrowser/#/R-CEL-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Caenorhabditis elegans 9254 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 9254 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 9254 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 9254 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 9254 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 9254 R-CFA-879585 https://reactome.org/PathwayBrowser/#/R-CFA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Canis familiaris 9254 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 9254 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 9254 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 9254 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 9254 R-DME-879585 https://reactome.org/PathwayBrowser/#/R-DME-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Drosophila melanogaster 9254 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 9254 R-DRE-879585 https://reactome.org/PathwayBrowser/#/R-DRE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Danio rerio 9254 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 9254 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 9254 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 9254 R-GGA-433578 https://reactome.org/PathwayBrowser/#/R-GGA-433578 phytoceramide + H2O => stearate + phytosphingosine IEA Gallus gallus 9254 R-GGA-433608 https://reactome.org/PathwayBrowser/#/R-GGA-433608 ceramide + H2O => stearate + sphingosine [endoplasmic reticulum] IEA Gallus gallus 9254 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 9254 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 9254 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 9254 R-GGA-879585 https://reactome.org/PathwayBrowser/#/R-GGA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Gallus gallus 9254 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 9254 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 9254 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 9254 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 9254 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 9254 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 9254 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 9254 R-HSA-5627891 https://reactome.org/PathwayBrowser/#/R-HSA-5627891 Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol TAS Homo sapiens 9254 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 9254 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 9254 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 9254 R-HSA-879585 https://reactome.org/PathwayBrowser/#/R-HSA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol TAS Homo sapiens 9254 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 9254 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 9254 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 9254 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 9254 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 9254 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 9254 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 9254 R-MMU-879585 https://reactome.org/PathwayBrowser/#/R-MMU-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Mus musculus 9254 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 9254 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 9254 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 9254 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 9254 R-RNO-879585 https://reactome.org/PathwayBrowser/#/R-RNO-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Rattus norvegicus 9254 R-SCE-879585 https://reactome.org/PathwayBrowser/#/R-SCE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Saccharomyces cerevisiae 9254 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 9254 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 9254 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 9254 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 9254 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 9254 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 9254 R-SSC-879585 https://reactome.org/PathwayBrowser/#/R-SSC-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Sus scrofa 9254 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 9254 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 9254 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 9254 R-XTR-879585 https://reactome.org/PathwayBrowser/#/R-XTR-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Xenopus tropicalis 93829 R-BTA-432164 https://reactome.org/PathwayBrowser/#/R-BTA-432164 Ca2+ influx into the post-synaptic cell IEA Bos taurus 93829 R-CEL-432164 https://reactome.org/PathwayBrowser/#/R-CEL-432164 Ca2+ influx into the post-synaptic cell IEA Caenorhabditis elegans 93829 R-CFA-432164 https://reactome.org/PathwayBrowser/#/R-CFA-432164 Ca2+ influx into the post-synaptic cell IEA Canis familiaris 93829 R-DME-432164 https://reactome.org/PathwayBrowser/#/R-DME-432164 Ca2+ influx into the post-synaptic cell IEA Drosophila melanogaster 93829 R-DRE-432164 https://reactome.org/PathwayBrowser/#/R-DRE-432164 Ca2+ influx into the post-synaptic cell IEA Danio rerio 93829 R-GGA-432164 https://reactome.org/PathwayBrowser/#/R-GGA-432164 Ca2+ influx into the post-synaptic cell IEA Gallus gallus 93829 R-HSA-432164 https://reactome.org/PathwayBrowser/#/R-HSA-432164 Ca2+ influx into the post-synaptic cell TAS Homo sapiens 93829 R-MMU-432164 https://reactome.org/PathwayBrowser/#/R-MMU-432164 Ca2+ influx into the post-synaptic cell IEA Mus musculus 93829 R-RNO-432164 https://reactome.org/PathwayBrowser/#/R-RNO-432164 Ca2+ influx into the post-synaptic cell IEA Rattus norvegicus 93829 R-SSC-432164 https://reactome.org/PathwayBrowser/#/R-SSC-432164 Ca2+ influx into the post-synaptic cell IEA Sus scrofa 93829 R-XTR-432164 https://reactome.org/PathwayBrowser/#/R-XTR-432164 Ca2+ influx into the post-synaptic cell IEA Xenopus tropicalis 9407 R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 9407 R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 9407 R-BTA-192430 https://reactome.org/PathwayBrowser/#/R-BTA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 9407 R-BTA-193362 https://reactome.org/PathwayBrowser/#/R-BTA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Bos taurus 9407 R-BTA-194121 https://reactome.org/PathwayBrowser/#/R-BTA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Bos taurus 9407 R-BTA-194130 https://reactome.org/PathwayBrowser/#/R-BTA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Bos taurus 9407 R-BTA-194153 https://reactome.org/PathwayBrowser/#/R-BTA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Bos taurus 9407 R-BTA-194187 https://reactome.org/PathwayBrowser/#/R-BTA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Bos taurus 9407 R-BTA-9733545 https://reactome.org/PathwayBrowser/#/R-BTA-9733545 Bile salts and acids bind ALB IEA Bos taurus 9407 R-BTA-9733960 https://reactome.org/PathwayBrowser/#/R-BTA-9733960 Bile salts and acids dissociate from ALB IEA Bos taurus 9407 R-BTA-9733964 https://reactome.org/PathwayBrowser/#/R-BTA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Bos taurus 9407 R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 9407 R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 9407 R-CEL-192430 https://reactome.org/PathwayBrowser/#/R-CEL-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 9407 R-CEL-194121 https://reactome.org/PathwayBrowser/#/R-CEL-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 9407 R-CEL-194130 https://reactome.org/PathwayBrowser/#/R-CEL-194130 Transport (influx) of bile salts and acids by OATP-A IEA Caenorhabditis elegans 9407 R-CEL-194153 https://reactome.org/PathwayBrowser/#/R-CEL-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Caenorhabditis elegans 9407 R-CEL-194187 https://reactome.org/PathwayBrowser/#/R-CEL-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 9407 R-CFA-193362 https://reactome.org/PathwayBrowser/#/R-CFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Canis familiaris 9407 R-CFA-194121 https://reactome.org/PathwayBrowser/#/R-CFA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Canis familiaris 9407 R-CFA-194130 https://reactome.org/PathwayBrowser/#/R-CFA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Canis familiaris 9407 R-CFA-194153 https://reactome.org/PathwayBrowser/#/R-CFA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Canis familiaris 9407 R-CFA-194187 https://reactome.org/PathwayBrowser/#/R-CFA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Canis familiaris 9407 R-CFA-9733545 https://reactome.org/PathwayBrowser/#/R-CFA-9733545 Bile salts and acids bind ALB IEA Canis familiaris 9407 R-CFA-9733960 https://reactome.org/PathwayBrowser/#/R-CFA-9733960 Bile salts and acids dissociate from ALB IEA Canis familiaris 9407 R-CFA-9733964 https://reactome.org/PathwayBrowser/#/R-CFA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Canis familiaris 9407 R-DDI-193362 https://reactome.org/PathwayBrowser/#/R-DDI-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 9407 R-DDI-194153 https://reactome.org/PathwayBrowser/#/R-DDI-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 9407 R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 9407 R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 9407 R-DME-192430 https://reactome.org/PathwayBrowser/#/R-DME-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 9407 R-DME-194121 https://reactome.org/PathwayBrowser/#/R-DME-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 9407 R-DME-194130 https://reactome.org/PathwayBrowser/#/R-DME-194130 Transport (influx) of bile salts and acids by OATP-A IEA Drosophila melanogaster 9407 R-DME-194153 https://reactome.org/PathwayBrowser/#/R-DME-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Drosophila melanogaster 9407 R-DME-194187 https://reactome.org/PathwayBrowser/#/R-DME-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 9407 R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 9407 R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 9407 R-DRE-192430 https://reactome.org/PathwayBrowser/#/R-DRE-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 9407 R-DRE-194121 https://reactome.org/PathwayBrowser/#/R-DRE-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Danio rerio 9407 R-DRE-194130 https://reactome.org/PathwayBrowser/#/R-DRE-194130 Transport (influx) of bile salts and acids by OATP-A IEA Danio rerio 9407 R-DRE-194187 https://reactome.org/PathwayBrowser/#/R-DRE-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Danio rerio 9407 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 9407 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 9407 R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 9407 R-GGA-193362 https://reactome.org/PathwayBrowser/#/R-GGA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Gallus gallus 9407 R-GGA-194130 https://reactome.org/PathwayBrowser/#/R-GGA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Gallus gallus 9407 R-GGA-194153 https://reactome.org/PathwayBrowser/#/R-GGA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Gallus gallus 9407 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus 9407 R-GGA-9733545 https://reactome.org/PathwayBrowser/#/R-GGA-9733545 Bile salts and acids bind ALB IEA Gallus gallus 9407 R-GGA-9733960 https://reactome.org/PathwayBrowser/#/R-GGA-9733960 Bile salts and acids dissociate from ALB IEA Gallus gallus 9407 R-GGA-9733964 https://reactome.org/PathwayBrowser/#/R-GGA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Gallus gallus 9407 R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 9407 R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 9407 R-HSA-192430 https://reactome.org/PathwayBrowser/#/R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 9407 R-HSA-193362 https://reactome.org/PathwayBrowser/#/R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region TAS Homo sapiens 9407 R-HSA-194121 https://reactome.org/PathwayBrowser/#/R-HSA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol TAS Homo sapiens 9407 R-HSA-194130 https://reactome.org/PathwayBrowser/#/R-HSA-194130 Transport (influx) of bile salts and acids by OATP-A TAS Homo sapiens 9407 R-HSA-194153 https://reactome.org/PathwayBrowser/#/R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region TAS Homo sapiens 9407 R-HSA-194187 https://reactome.org/PathwayBrowser/#/R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol TAS Homo sapiens 9407 R-HSA-9733545 https://reactome.org/PathwayBrowser/#/R-HSA-9733545 Bile salts and acids bind ALB TAS Homo sapiens 9407 R-HSA-9733960 https://reactome.org/PathwayBrowser/#/R-HSA-9733960 Bile salts and acids dissociate from ALB TAS Homo sapiens 9407 R-HSA-9733964 https://reactome.org/PathwayBrowser/#/R-HSA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region TAS Homo sapiens 9407 R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 9407 R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 9407 R-MMU-192430 https://reactome.org/PathwayBrowser/#/R-MMU-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 9407 R-MMU-193362 https://reactome.org/PathwayBrowser/#/R-MMU-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Mus musculus 9407 R-MMU-194121 https://reactome.org/PathwayBrowser/#/R-MMU-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Mus musculus 9407 R-MMU-194130 https://reactome.org/PathwayBrowser/#/R-MMU-194130 Transport (influx) of bile salts and acids by OATP-A IEA Mus musculus 9407 R-MMU-194153 https://reactome.org/PathwayBrowser/#/R-MMU-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Mus musculus 9407 R-MMU-194187 https://reactome.org/PathwayBrowser/#/R-MMU-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Mus musculus 9407 R-MMU-9733545 https://reactome.org/PathwayBrowser/#/R-MMU-9733545 Bile salts and acids bind ALB IEA Mus musculus 9407 R-MMU-9733960 https://reactome.org/PathwayBrowser/#/R-MMU-9733960 Bile salts and acids dissociate from ALB IEA Mus musculus 9407 R-MMU-9733964 https://reactome.org/PathwayBrowser/#/R-MMU-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Mus musculus 9407 R-PFA-193362 https://reactome.org/PathwayBrowser/#/R-PFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Plasmodium falciparum 9407 R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 9407 R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 9407 R-RNO-192430 https://reactome.org/PathwayBrowser/#/R-RNO-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 9407 R-RNO-193362 https://reactome.org/PathwayBrowser/#/R-RNO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 9407 R-RNO-194121 https://reactome.org/PathwayBrowser/#/R-RNO-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Rattus norvegicus 9407 R-RNO-194130 https://reactome.org/PathwayBrowser/#/R-RNO-194130 Transport (influx) of bile salts and acids by OATP-A IEA Rattus norvegicus 9407 R-RNO-194153 https://reactome.org/PathwayBrowser/#/R-RNO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 9407 R-RNO-194187 https://reactome.org/PathwayBrowser/#/R-RNO-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Rattus norvegicus 9407 R-RNO-9733545 https://reactome.org/PathwayBrowser/#/R-RNO-9733545 Bile salts and acids bind ALB IEA Rattus norvegicus 9407 R-RNO-9733960 https://reactome.org/PathwayBrowser/#/R-RNO-9733960 Bile salts and acids dissociate from ALB IEA Rattus norvegicus 9407 R-RNO-9733964 https://reactome.org/PathwayBrowser/#/R-RNO-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 9407 R-SCE-194153 https://reactome.org/PathwayBrowser/#/R-SCE-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Saccharomyces cerevisiae 9407 R-SPO-193362 https://reactome.org/PathwayBrowser/#/R-SPO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 9407 R-SPO-194153 https://reactome.org/PathwayBrowser/#/R-SPO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 9407 R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 9407 R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 9407 R-SSC-192430 https://reactome.org/PathwayBrowser/#/R-SSC-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 9407 R-SSC-193362 https://reactome.org/PathwayBrowser/#/R-SSC-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Sus scrofa 9407 R-SSC-194121 https://reactome.org/PathwayBrowser/#/R-SSC-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Sus scrofa 9407 R-SSC-194130 https://reactome.org/PathwayBrowser/#/R-SSC-194130 Transport (influx) of bile salts and acids by OATP-A IEA Sus scrofa 9407 R-SSC-194153 https://reactome.org/PathwayBrowser/#/R-SSC-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Sus scrofa 9407 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa 9407 R-SSC-9733545 https://reactome.org/PathwayBrowser/#/R-SSC-9733545 Bile salts and acids bind ALB IEA Sus scrofa 9407 R-SSC-9733960 https://reactome.org/PathwayBrowser/#/R-SSC-9733960 Bile salts and acids dissociate from ALB IEA Sus scrofa 9407 R-SSC-9733964 https://reactome.org/PathwayBrowser/#/R-SSC-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Sus scrofa 9407 R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 9407 R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 9407 R-XTR-192430 https://reactome.org/PathwayBrowser/#/R-XTR-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 9407 R-XTR-194121 https://reactome.org/PathwayBrowser/#/R-XTR-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 9407 R-XTR-194153 https://reactome.org/PathwayBrowser/#/R-XTR-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 9407 R-XTR-194187 https://reactome.org/PathwayBrowser/#/R-XTR-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 9407 R-XTR-9733545 https://reactome.org/PathwayBrowser/#/R-XTR-9733545 Bile salts and acids bind ALB IEA Xenopus tropicalis 9407 R-XTR-9733960 https://reactome.org/PathwayBrowser/#/R-XTR-9733960 Bile salts and acids dissociate from ALB IEA Xenopus tropicalis 9407 R-XTR-9733964 https://reactome.org/PathwayBrowser/#/R-XTR-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 94119 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 94119 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 94119 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 94119 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 94119 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 94119 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 94119 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 94119 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 94119 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 94119 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 94119 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 94119 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 94119 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 94119 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 94119 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 94119 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 94119 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 94119 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 94119 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 94119 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 94119 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 9434 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(34-41) binds to AGTR1 IEA Bos taurus 9434 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGRT1 IEA Bos taurus 9434 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(34-41) binds to AGTR1 IEA Caenorhabditis elegans 9434 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGRT1 IEA Caenorhabditis elegans 9434 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(34-41) binds to AGTR1 IEA Canis familiaris 9434 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGRT1 IEA Canis familiaris 9434 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(34-41) binds to AGTR1 IEA Drosophila melanogaster 9434 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGRT1 IEA Drosophila melanogaster 9434 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(34-41) binds to AGTR1 IEA Danio rerio 9434 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGRT1 IEA Danio rerio 9434 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(34-41) binds to AGTR1 IEA Gallus gallus 9434 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGRT1 IEA Gallus gallus 9434 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(34-41) binds to AGTR1 TAS Homo sapiens 9434 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGRT1 TAS Homo sapiens 9434 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(34-41) binds to AGTR1 IEA Mus musculus 9434 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGRT1 IEA Mus musculus 9434 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(34-41) binds to AGTR1 IEA Rattus norvegicus 9434 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGRT1 IEA Rattus norvegicus 9434 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(34-41) binds to AGTR1 IEA Sus scrofa 9434 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGRT1 IEA Sus scrofa 94385 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 94385 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 94385 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 94385 R-BTA-9015379 https://reactome.org/PathwayBrowser/#/R-BTA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Bos taurus 94385 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 94385 R-CFA-9015379 https://reactome.org/PathwayBrowser/#/R-CFA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Canis familiaris 94385 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 94385 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 94385 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 94385 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 94385 R-GGA-9015379 https://reactome.org/PathwayBrowser/#/R-GGA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Gallus gallus 94385 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 94385 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 94385 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 94385 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 94385 R-HSA-9015379 https://reactome.org/PathwayBrowser/#/R-HSA-9015379 Factor IIa inhibitors (compounds) binds IIa TAS Homo sapiens 94385 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 94385 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 94385 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 94385 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 94385 R-MMU-9015379 https://reactome.org/PathwayBrowser/#/R-MMU-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Mus musculus 94385 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 94385 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 94385 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 94385 R-RNO-9015379 https://reactome.org/PathwayBrowser/#/R-RNO-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Rattus norvegicus 94385 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 94385 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 94385 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 94385 R-SSC-9015379 https://reactome.org/PathwayBrowser/#/R-SSC-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Sus scrofa 94385 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 94385 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 94385 R-XTR-9015379 https://reactome.org/PathwayBrowser/#/R-XTR-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Xenopus tropicalis 9445 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 9445 R-BTA-9617370 https://reactome.org/PathwayBrowser/#/R-BTA-9617370 α1-antagonists bind ADRA1A,B,D IEA Bos taurus 9445 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 9445 R-CEL-9617370 https://reactome.org/PathwayBrowser/#/R-CEL-9617370 α1-antagonists bind ADRA1A,B,D IEA Caenorhabditis elegans 9445 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 9445 R-CFA-9617370 https://reactome.org/PathwayBrowser/#/R-CFA-9617370 α1-antagonists bind ADRA1A,B,D IEA Canis familiaris 9445 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 9445 R-DME-9617370 https://reactome.org/PathwayBrowser/#/R-DME-9617370 α1-antagonists bind ADRA1A,B,D IEA Drosophila melanogaster 9445 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 9445 R-DRE-9617370 https://reactome.org/PathwayBrowser/#/R-DRE-9617370 α1-antagonists bind ADRA1A,B,D IEA Danio rerio 9445 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 9445 R-GGA-9617370 https://reactome.org/PathwayBrowser/#/R-GGA-9617370 α1-antagonists bind ADRA1A,B,D IEA Gallus gallus 9445 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 9445 R-HSA-9617370 https://reactome.org/PathwayBrowser/#/R-HSA-9617370 α1-antagonists bind ADRA1A,B,D TAS Homo sapiens 9445 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 9445 R-MMU-9617370 https://reactome.org/PathwayBrowser/#/R-MMU-9617370 α1-antagonists bind ADRA1A,B,D IEA Mus musculus 9445 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 9445 R-RNO-9617370 https://reactome.org/PathwayBrowser/#/R-RNO-9617370 α1-antagonists bind ADRA1A,B,D IEA Rattus norvegicus 9445 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 9445 R-SSC-9617370 https://reactome.org/PathwayBrowser/#/R-SSC-9617370 α1-antagonists bind ADRA1A,B,D IEA Sus scrofa 9445 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 9445 R-XTR-9617370 https://reactome.org/PathwayBrowser/#/R-XTR-9617370 α1-antagonists bind ADRA1A,B,D IEA Xenopus tropicalis 94562 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 9463 R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 9463 R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 9463 R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 9463 R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 9463 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 9463 R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 9463 R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 9463 R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 9463 R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 9463 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 9463 R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 94777 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 94777 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 94777 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 94777 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 94777 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 94777 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 94777 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 94777 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 94777 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 94777 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 95049 R-BTA-9657608 https://reactome.org/PathwayBrowser/#/R-BTA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Bos taurus 95049 R-CEL-9657608 https://reactome.org/PathwayBrowser/#/R-CEL-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Caenorhabditis elegans 95049 R-CFA-9657608 https://reactome.org/PathwayBrowser/#/R-CFA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Canis familiaris 95049 R-DME-9657608 https://reactome.org/PathwayBrowser/#/R-DME-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Drosophila melanogaster 95049 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus 95049 R-HSA-9657608 https://reactome.org/PathwayBrowser/#/R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK TAS Homo sapiens 95049 R-MMU-9657608 https://reactome.org/PathwayBrowser/#/R-MMU-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Mus musculus 95049 R-RNO-9657608 https://reactome.org/PathwayBrowser/#/R-RNO-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Rattus norvegicus 95049 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa 9534 R-BTA-965067 https://reactome.org/PathwayBrowser/#/R-BTA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Bos taurus 9534 R-CFA-965067 https://reactome.org/PathwayBrowser/#/R-CFA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Canis familiaris 9534 R-HSA-965067 https://reactome.org/PathwayBrowser/#/R-HSA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP TAS Homo sapiens 9534 R-HSA-997381 https://reactome.org/PathwayBrowser/#/R-HSA-997381 TDPK phosphorylates ThDP to ThTP TAS Homo sapiens 9534 R-MMU-965067 https://reactome.org/PathwayBrowser/#/R-MMU-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Mus musculus 9534 R-RNO-965067 https://reactome.org/PathwayBrowser/#/R-RNO-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Rattus norvegicus 9534 R-SSC-965067 https://reactome.org/PathwayBrowser/#/R-SSC-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Sus scrofa 9534 R-XTR-965067 https://reactome.org/PathwayBrowser/#/R-XTR-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Xenopus tropicalis 9588 R-BTA-417829 https://reactome.org/PathwayBrowser/#/R-BTA-417829 P2RY12 binds ADP IEA Bos taurus 9588 R-BTA-9611277 https://reactome.org/PathwayBrowser/#/R-BTA-9611277 P2RY12 binds P2RY12 antagonists IEA Bos taurus 9588 R-CFA-417829 https://reactome.org/PathwayBrowser/#/R-CFA-417829 P2RY12 binds ADP IEA Canis familiaris 9588 R-CFA-9611277 https://reactome.org/PathwayBrowser/#/R-CFA-9611277 P2RY12 binds P2RY12 antagonists IEA Canis familiaris 9588 R-DRE-417829 https://reactome.org/PathwayBrowser/#/R-DRE-417829 P2RY12 binds ADP IEA Danio rerio 9588 R-DRE-9611277 https://reactome.org/PathwayBrowser/#/R-DRE-9611277 P2RY12 binds P2RY12 antagonists IEA Danio rerio 9588 R-HSA-417829 https://reactome.org/PathwayBrowser/#/R-HSA-417829 P2RY12 binds ADP TAS Homo sapiens 9588 R-HSA-9611277 https://reactome.org/PathwayBrowser/#/R-HSA-9611277 P2RY12 binds P2RY12 antagonists TAS Homo sapiens 9588 R-MMU-417829 https://reactome.org/PathwayBrowser/#/R-MMU-417829 P2RY12 binds ADP IEA Mus musculus 9588 R-MMU-9611277 https://reactome.org/PathwayBrowser/#/R-MMU-9611277 P2RY12 binds P2RY12 antagonists IEA Mus musculus 9588 R-RNO-417829 https://reactome.org/PathwayBrowser/#/R-RNO-417829 P2RY12 binds ADP IEA Rattus norvegicus 9588 R-RNO-9611277 https://reactome.org/PathwayBrowser/#/R-RNO-9611277 P2RY12 binds P2RY12 antagonists IEA Rattus norvegicus 9588 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa 9588 R-SSC-9611277 https://reactome.org/PathwayBrowser/#/R-SSC-9611277 P2RY12 binds P2RY12 antagonists IEA Sus scrofa 9588 R-XTR-417829 https://reactome.org/PathwayBrowser/#/R-XTR-417829 P2RY12 binds ADP IEA Xenopus tropicalis 9588 R-XTR-9611277 https://reactome.org/PathwayBrowser/#/R-XTR-9611277 P2RY12 binds P2RY12 antagonists IEA Xenopus tropicalis 9613 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 9613 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 9613 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 9613 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 9613 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 9613 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 9613 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 9613 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 9613 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 9649 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 9649 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 9649 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 9649 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 9649 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 9649 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 9649 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 9649 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 9649 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 9649 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 9649 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 9649 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 9927 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(34-41) binds to AGTR1 IEA Bos taurus 9927 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGRT1 IEA Bos taurus 9927 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(34-41) binds to AGTR1 IEA Caenorhabditis elegans 9927 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGRT1 IEA Caenorhabditis elegans 9927 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(34-41) binds to AGTR1 IEA Canis familiaris 9927 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGRT1 IEA Canis familiaris 9927 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(34-41) binds to AGTR1 IEA Drosophila melanogaster 9927 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGRT1 IEA Drosophila melanogaster 9927 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(34-41) binds to AGTR1 IEA Danio rerio 9927 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGRT1 IEA Danio rerio 9927 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(34-41) binds to AGTR1 IEA Gallus gallus 9927 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGRT1 IEA Gallus gallus 9927 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(34-41) binds to AGTR1 TAS Homo sapiens 9927 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGRT1 TAS Homo sapiens 9927 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(34-41) binds to AGTR1 IEA Mus musculus 9927 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGRT1 IEA Mus musculus 9927 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(34-41) binds to AGTR1 IEA Rattus norvegicus 9927 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGRT1 IEA Rattus norvegicus 9927 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(34-41) binds to AGTR1 IEA Sus scrofa 9927 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGRT1 IEA Sus scrofa 9948 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 9948 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 9948 R-BTA-9678766 https://reactome.org/PathwayBrowser/#/R-BTA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Bos taurus 9948 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 9948 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 9948 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 9948 R-CFA-9678766 https://reactome.org/PathwayBrowser/#/R-CFA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Canis familiaris 9948 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 9948 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 9948 R-DRE-9678766 https://reactome.org/PathwayBrowser/#/R-DRE-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Danio rerio 9948 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 9948 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 9948 R-GGA-9678766 https://reactome.org/PathwayBrowser/#/R-GGA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Gallus gallus 9948 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 9948 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 9948 R-HSA-9678766 https://reactome.org/PathwayBrowser/#/R-HSA-9678766 CYP3A4 binds CYP3A4 inhibitors TAS Homo sapiens 9948 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 9948 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 9948 R-MMU-9678766 https://reactome.org/PathwayBrowser/#/R-MMU-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Mus musculus 9948 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 9948 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 9948 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 9948 R-RNO-9678766 https://reactome.org/PathwayBrowser/#/R-RNO-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Rattus norvegicus 9948 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 9948 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 9948 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 9948 R-SSC-9678766 https://reactome.org/PathwayBrowser/#/R-SSC-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Sus scrofa 9948 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 9948 R-XTR-9678766 https://reactome.org/PathwayBrowser/#/R-XTR-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Xenopus tropicalis